bluuebunny/crossref_metadata_2025 huggingface dataset:
Making agricultural landscapes more sustainable for freshwater biodiversity: a case study from southern England
Authors: Davies Bella , Biggs Jeremy , Williams Penny , Thompson Stewart
Published: December 2008

Agriculture is known to have a range of deleterious impacts on freshwater habitats and biota and many countries have introduced measures to attempt to mitigate these impacts through agri‐environment initiatives. Despite the protection they provide, water bodies (any discrete body of surface fresh water) in farmland landscapes commonly remain impaired by agriculture. In some areas of the UK there have been calls to halt farming completely, indicating that the measures offered for the widespread protection of aquatic systems, particularly the use of buffer strips, may not be extensive enough to provide sufficient protection for freshwater biota.

This study investigated whether existing agri‐environment measures for the widespread protection of aquatic habitats could be better deployed to provide a higher level of protection for the aquatic macrophytes and macroinvertebrates of a study area in southern England.

Reserve selection procedures were used to reallocate the area of land that could be remunerated under the Environmental Stewardship scheme as buffer strips bordering water bodies, so that a higher level of protection was provided for both the richness and rarity of aquatic species in the study area.

Almost 395 ha were available for reallocation in the reserve selection process, which was found to provide a satisfactory level of protection for up to 90% of the surveyed species.

The results showed that the agri‐environment scheme in England has a great deal of potential to provide more effective protection for the aquatic biodiversity of agricultural landscapes if measures are targeted.

Copyright © 2008 John Wiley & Sons, Ltd.
BVideoQA: Online English/Chinese bilingual video question answering
Authors: Lee Yue‐Shi , Wu Yu‐Chieh , Yang Jie‐Chi
Published: December 2008

This article presents a bilingual video question answering (QA) system, namely BVideoQA, which allows users to retrieve Chinese videos through English or Chinese natural language questions. Our method first extracts an optimal one‐to‐one string pattern matching according to the proposed dense and longN‐gram match. On the basis of the matched string patterns, it gives a passage score based on our term‐weighting scheme. The main contributions of this approach to multimedia information retrieval literatures include: (a) development of a truly bilingual video QA system, (b) presentation of a robust bilingual passage retrieval algorithm to handle no‐word‐boundary languages such as Chinese and Japanese, (c) development of a large‐scale bilingual video QA corpus for system evaluation, and (d) comparisons of seven top‐performing retrieval methods under the fair conditions. The experimental studies indicate that our method is superior to other existing approaches in terms of precision and main rank reciprocal rates. When ported to English, encouraging empirical results also are obtained. Our method is very important to Asian‐like languages since the development of a word tokenizer is optional.
Update on prevention of folic acid‐preventable spina bifida and anencephaly
Authors: Bell Karen N. , Oakley Godfrey P.
Published: December 2008

BACKGROUND: The number of countries fortifying wheat and maize flour with folic acid has increased in the past 2 years. Folic acid prevents most cases of spina bifida and anencephaly by raising serum folate levels among women capable of bearing children, as does encouraging women to consume folic acid supplements prior to pregnancy. METHODS: The progress in preventing these serious birth defects can be measured by tracking the number of countries now fortifying and program coverage in each. Country estimates of the number of pregnancies affected by spina bifida and anencephaly are calculated using a prefortification birth prevalence baseline and estimates of the proportion prevented by wheat and maize flour fortified with folic acid. RESULTS: Current fortification programs are preventing about 22,000, or 9% of the estimated folic acid‐preventable spina bifida and anencephaly cases. This represents an annual global decrease of about 6,600 folic acid‐preventable spina bifida and anencephaly cases since 2006. CONCLUSIONS: The pace of preventing these serious birth defects can be accelerated if more countries require fortification of both wheat and maize flour and if regulators set fortification levels high enough to increase a woman's daily average consumption of folic acid to 400 mcg. Birth Defects Research (Part A), 2009. © 2008 Wiley‐Liss, Inc.
Regeneration: Rewarding, but potentially risky
Authors: Egger Bernhard
Published: December 2008

Some bilaterally symmetric animals, such as flatworms, annelids, and nemerteans, are renowned for their outstanding regeneration capacity—even a fraction of the body can give rise to a complete new animal. However, not all species of these taxa can regenerate equally well—some cannot regenerate at all. If regeneration was purely beneficial, why cannot all of members of the flat, round, and ribbon worms regenerate? At that, why cannot all other bilaterians, including humans, regenerate as well? Regeneration capacity is an obvious advantage in accidental, predatory, and parasitic loss of body parts and is also closely intertwined with asexual reproduction strategies. Regeneration is suspected to play a role in life span extension or even rejuvenation. An answer for reduced or missing regeneration capacity in many species may be found in limitations of the body plan, high costs, and inherent dangers of regeneration. Defects in adults and juveniles are shown, and similarities between development and regeneration are pointed out. With a focus on some worms, but also highlighting comparisons with other animal taxa, putative reasons for a limited and an advanced regeneration capacity are discussed in this article. Birth Defects Research (Part C) 84:257–264, 2008. © 2008 Wiley‐Liss, Inc.
Stenting for a symptomatic posterior cerebral artery stenosis
Authors: Xu Gelin , Zheng Ling , Zhou Zhiming , Liu Xinfeng
Published: December 2008

Evolvement of endovascular devices and increase of operator expertise have made angioplasty and stenting in intracranial vessels technically possible. Stenting has been reported in treating stenosis in middle and anterior cerebral arteries with favorable outcomes. However, the feasibility of stenting for stenosis in posterior cerebral artery (PCA) has not been established. We report a patient with progressive focal cerebral ischemic symptoms, which were arrested after reconstruction of the associated PCA stenosis with stenting. © 2008 Wiley‐Liss, Inc.
Rotational vs. standard coronary angiography: An image content analysis
Authors: Garcia Joel A. , Agostoni Pierfrancesco , Green Nathan E. , Maddux James T. , Chen S.‐Y. James , Messenger John C. , Casserly Ivan P. , Hansgen Adam , Wink Onno , Movassaghi Babak , Groves Bertron M. , Van Den Heuvel Paul , Verheye Stefan , Van Langenhove Glenn , Vermeersch Paul , Van den Branden Frank , Yeghiazarians Yerem , Michaels Andrew D. , Carroll John D.
Published: December 2008

Objective: To evaluate the clinical utility of images acquired from rotational coronary angiographic (RA) acquisitions compared to standard “fixed” coronary angiography (SA). Background: RA is a novel angiographic modality that has been enabled by new gantry systems that allow calibrated automatic angiographic rotations and has been shown to reduce radiation and contrast exposure compared to SA. RA provides a dynamic multiple‐angle perspective of the coronaries during a single contrast injection. Methods: The screening adequacy, lesion assessment, and a quantitative coronary analysis (QCA) of both SA and RA were compared by independent blinded review in 100 patients with coronary artery disease (CAD). Results: SA and RA recognize a similar total number of lesions (P = 0.61). The qualitative assessment of lesion characteristics and severity between modalities was comparable and lead to similar clinical decisions. Visualization of several vessel segments (diagonal, distal RCA, postero‐lateral branches and posterior‐descending) was superior with RA when compared to SA (P < 0.05). A QCA comparison (MLD, MLA, LL, % DS) revealed no difference between SA and RA. The volume of contrast (23.5 ± 3.1 mL vs. 39.4 ± 4.1; P = 0.0001), total radiation exposure (27.1 ± 4 vs. 32.1 ± 3.8 Gycm2; P = 0.002) and image acquisition time (54.3 ± 36.8 vs. 77.67 ± 49.64 sec; P = 0.003) all favored RA. Conclusion: Coronary lesion assessment, coronary screening adequacy, and QCA evaluations are comparable in SA and RA acquisition modalities in the diagnosis of CAD however RA decreases contrast volume, image acquisition time, and radiation exposure. © 2009 Wiley‐Liss, Inc.
Electric‐Field Triggered Controlled Release of Bioactive Volatiles from Imine‐Based Liquid Crystalline Phases
Authors: Herrmann Andreas , Giuseppone Nicolas , Lehn Jean‐Marie
Published: December 2008

Application of an electric field to liquid crystalline film forming imines with negative dielectric anisotropy, such as N‐(4‐methoxybenzylidene)‐4‐butylaniline (MBBA, 1), results in the expulsion of compounds that do not participate in the formation of the liquid crystalline phase. Furthermore, amines and aromatic aldehydes undergo component exchange with the imine by generating constitutional dynamic libraries. The strength of the electric field and the duration of its application to the liquid crystalline film influence the release rate of the expelled compounds and, at the same time, modulate the equilibration of the dynamic libraries. The controlled release of volatile organic molecules with different chemical functionalities from the film was quantified by dynamic headspace analysis. In all cases, higher headspace concentrations were detected in the presence of an electric field. These results point to the possibility of using imine‐based liquid crystalline films to build devices for the controlled release of a broad variety of bioactive volatiles as a direct response to an external electric signal.
Rainbow Perylene Monoimides: Easy Control of Optical Properties
Authors: Li Chen , Schöneboom Jan , Liu Zhihong , Pschirer Neil G. , Erk Peter , Herrmann Andreas , Müllen Klaus
Published: December 2008

Perylene dyes have been widely used as photoreceptors in organic photovoltaics because of their outstanding photo‐, thermal and chemical stability as well as their excellent photophysical properties. Herein we describe a novel generation of perylene dyes based on N‐(2,6‐diisopropylphenyl)‐perylene‐3,4‐dicarboximide. The optical properties of these novel perylenes can be finely tuned via the substituents in the 1‐, 6‐ and 9‐positions of the perylene core. The facile synthesis, tunable orbital and absorption properties, and electrochemical potentials help us to design efficient perylene sensitizers for solar‐cell applications.
ChemInform Abstract: Band Structure Features of Nonlinear Optical Yttrium Aluminum Borate Crystal
Authors: Reshak Ali H. , Auluck S. , Majchrowski A. , Kityk I. V.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Molecular Clusters [Bi10Au2](EBi3X9)2 (E: As, Bi; X: Cl, Br) — Synthesis, Crystal Structures, Twinning and Chemical Bonding.
Authors: Wahl Bernhard , Ruck Michael
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Uniform Colloidal Alkaline Earth Metal Fluoride Nanocrystals: Nonhydrolytic Synthesis and Luminescence Properties.
Authors: Quan Zewei , Yang Dongmei , Yang Piaoping , Zhang Xiaoming , Lian Hongzhou , Liu Xiaoming , Lin Jun
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The First Example of the Tetraselenidostannate Anion [SnSe4]4‐ as a Chelating Ligand to a Lanthanide Complex Ion: Solvothermal Synthesis and Characterization of Lanthanoid Selenidostannates [Hdien][Ln(dien)2(μ‐SnSe4)] (Ln: Sm, Eu) and [Eu2(dien)4(μ‐OH)2] Sn2Se6.
Authors: Zhu Ai‐Mei , Jin Qin‐Yan , Jia Ding‐Xian , Gu Jian‐Sheng , Zhang Yong
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polygallide RE2MGa9Ge2 (RE: Ce, Sm; M: Ni, Co) Phases Grown in Molten Gallium.
Authors: Zhuravleva Marina A. , Kanatzidis Mercouri G.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Pot Organocatalytic Domino Michael/α‐Alkylation Reactions: Direct Catalytic Enantioselective Cyclopropanation and Cyclopentanation Reactions.
Authors: Ibrahem Ismail , Zhao Gui‐Ling , Rios Ramon , Vesely Jan , Sunden Henrik , Dziedzic Pawel , Cordova Armando
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral Tetrafluorobenzobarrelenes as Highly Efficient Ligands for the Rhodium‐Catalyzed Asymmetric 1,4‐Addition of Arylboronic Acids.
Authors: Nishimura Takahiro , Nagaosa Makoto , Hayashi Tamio
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nucleophilic Addition of Phenol Derivatives to Methyl 1‐Nitrocyclopropanecarboxylates.
Authors: Lifchits Olga , Alberico Dino , Zakharian Irina , Charette Andre B.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fullerene Complexes with Palladium and Rhodium as Catalysts for Acetylenic Bond Hydrogenation.
Authors: Starodubtseva Eugenia V. , Sokolov Viatcheslav I. , Bashilov Vasily V. , Novikov Yurii N. , Martynova Ekaterina V. , Vinogradov Maxim G. , Turova Olga V.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Perfluoroalkylation Through Cross‐Metathesis Between Alkenes and (Perfluoroalkyl)propenes.
Authors: Eignerova Barbara , Dracinsky Martin , Kotora Martin
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave Acceleration in DABAL‐Me3‐Mediated Amide Formation.
Authors: Glynn Daniel , Bernier David , Woodward Simon
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Enantioselective Cyclopropanation of Allylic Alcohols Using Recyclable Fluorous Disulfonamide Ligand.
Authors: Miura Tsuyoshi , Itoh Keisuke , Yasaku Yumi , Koyata Naka , Murakami Yasuoki , Imai Nobuyuki
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Stereodefined Substituted Cycloalkenes by a One‐Pot Catalytic Boronation—Allylation—Metathesis Sequence.
Authors: Selander Nicklas , Szabo Kalman J.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: CuI/Iodine‐Mediated Homocoupling Reaction of Terminal Alkynes to 1,3‐Diynes.
Authors: Li Dafeng , Yin Kun , Li Jian , Jia Xueshun
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pd‐Catalyzed Oxidative Amidation of Aldehydes with Hydrogen Peroxide.
Authors: Suto Yutaka , Yamagiwa Noriyuki , Torisawa Yasuhiro
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Direct Carbon—Carbon Bond Formation via Chemoselective Soft Enolization of Thioesters: A Remarkably Simple and Versatile Crossed Claisen Reaction Applied to the Synthesis of LY294002.
Authors: Zhou Guoqiang , Lim Daniel , Coltart Don M.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Iminodiacetic Acid Immobilized on pH‐Responsive Polymeric Microspheres: Efficient Quasi‐Homogeneous Catalyst for Suzuki and Heck Reactions in Aqueous Solution.
Authors: Zhang Jianzheng , Zhang Wangqing , Wang Yao , Zhang Minchao
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pd‐Catalyzed Efficient One‐Pot Sequential Cross‐Coupling Reactions of Aryl Dihalides.
Authors: Zhang Xiaoming , Liu Ailing , Chen Wanzhi
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A General and Efficient Synthesis of Substituted Fluorenes and Heterocycle‐Fused Indenes Containing Thiophene or Indole Rings Utilizing a Suzuki—Miyaura Coupling and Acid‐Catalyzed Friedel—Crafts Reactions as Key Steps.
Authors: Li Guijie , Wang Erjuan , Chen Haoyi , Li Hongfeng , Liu Yuanhong , Wang Peng George
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polar [3 + 2] Cycloaddition of Ketones with Electrophilically Activated Carbonyl Ylides. Synthesis of Spirocyclic Dioxolane Indolinones.
Authors: Bentabed‐Ababsa Ghenia , Derdour Aicha , Roisnel Thierry , Saez Jose A. , Domingo Luis R. , Mongin Florence
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Discovery of Long‐Wavelength Photoactivatable Diaryltetrazoles for Bioorthogonal 1,3‐Dipolar Cycloaddition Reactions.
Authors: Wang Yizhong , Hu Wen J. , Song Wenjiao , Lim Reyna K. V. , Lin Qing
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Heteropoly Acid as Efficient, Cost‐Effective, and Recyclable Solid Acid for the Rapid Synthesis of Substituted Imidazolines.
Authors: Yadav J. S. , Reddy B. V. Subba , Pandurangam T. , Reddy U. V. Subba
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Copper‐Catalyzed Oxidative sp3 C—H Bond Arylation with Aryl Boronic Acids.
Authors: Basle Olivier , Li Chao‐Jun
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Z‐2‐Methyl‐6‐R‐1,2,3,4‐tetrahydro‐4‐quinolinecarboxylic Acids (II).
Authors: Zhuravleva Yu. A. , Zimichev A. V. , Zemtsova M. N. , Klimochkin Yu. N.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design, Synthesis, and Biological Activities of Conformationally Restricted Analogues of Primaquine with a 1,10‐Phenanthroline Framework.
Authors: Sall Cheikh , Yapi Ange‐Desire , Desbois Nicolas , Chevalley Severine , Chezal Jean‐Michel , Tan Kimny , Teulade Jean‐Claude , Valentin Alexis , Blache Yves.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chloro(trimethyl)silane‐Catalyzed Three‐Component Condensation of Diethyl 3,3′‐(1,3‐Phenylene)bis(3‐oxopropanoate) with Aromatic Aldehyde and Urea. New Synthesis of Diethyl 4,4′‐(1,3‐Phenylene)bis (2‐oxo‐1,2,3,6‐tetrahydropyrimidine‐5‐carboxylates) (IV).
Authors: Vdovina S. V. , Mustakimova L. V. , Mamedov V. A.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polyfused Nitrogen Heterocycles. Part 19. Oxidative Imidazo‐Fusion of 3‐Benzoylquinoxalin‐2‐ones with Benzylamines in the Synthesis of Bis(imidazo[1,5‐a]quinoxalin‐1‐ and ‐5‐yl) Derivatives.
Authors: Kalinin A. A. , Mamedov V. A.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mild Addition of 2‐Pyrene to Pyrrolo[2,1‐c][1,4]benzoxazine‐1,2,4‐trione.
Authors: Babenysheva A. V. , Maslivets A. N.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Green Protocol for Synthesis of Benzo‐Fused N,S‐, N,O‐ and N,N‐Heterocycles in Water.
Authors: Zhang Qing‐Yi , Liu Bo‐Kai , Chen Wan‐Qin , Wu Qi , Lin Xian‐Fu
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Facile Synthesis of 2‐(Substituted amino)‐4H‐thieno[3,2‐e]‐1,3‐thiazin‐4‐ones.
Authors: Abu‐El‐Halawa Rajab , Sarabi Alaa , El‐Abadelah Mustafa M.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Eco‐Friendly Synthesis of 1,4‐Benzodiazepine‐2,5‐diones in the Ionic Liquid [bmim]Br.
Authors: Jadidi Khosrow , Ghahremanzadeh Ramin , Asgari Davoud , Eslami Parisa , Arvin‐Nezhad Hamid
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Synthesis of Optically Active Alkanephosphonates via Rhodium‐Catalyzed Asymmetric Hydrogenation of β‐Substituted α,β‐Unsaturated Phosphonates with Ferrocene‐Based Monophosphoramidite Ligands.
Authors: Duan Zheng‐Chao , Hu Xiang‐Ping , Wang Dao‐Yong , Huang Jia‐Di , Yu Sai‐Bo , Deng Jun , Zheng Zhuo
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of Substituted Selenophenes Based on the First Palladium(0)‐Catalyzed Cross‐Coupling Reactions of Tetrabromoselenophene.
Authors: Tung Dang Thanh , Villinger Alexander , Langer Peter
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Lacitemzine, a Novel Sesquiterpene Acid from the Tunisian Plant Pulicaria laciniata (Coss. et Kral.) Thell.
Authors: Ghouila Hatem , Beyaoui Ahlem , Jannet Hichem Ben , Hamdi Besma , Salah Abdelhamid Ben , Mighri Zine
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Preparation of 2,3‐Dideoxy‐3‐C‐ [(α‐D‐Galactopyranosyl)methyl]‐D‐arabino‐hexopyranose and 2,3‐Dideoxy‐3‐C‐ [(α‐D‐Galactopyranosyl)methyl]‐L‐arabino‐hexopyranose.
Authors: Parkan Kamil , Vich Ondrej , Dvorakova Hana , Kniezo Ladislav
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of L‐Guluronic Acid Alginates.
Authors: Dinkelaar Jasper , van den Bos Leendert J. , Hogendorf Wouter F. J. , Lodder Gerrit , Overkleeft Herman S. , Codee Jeroen D. C. , van der Marel Gijsbert A.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Antibacterial Quinone Metabolites from the Brown Alga, Sargassum sagamianum.
Authors: Horie Shohei , Tsutsumi Shinsuke , Takada Yuuki , Kimura Junji
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Quantum Nanomagnets: From Relaxation to Coherence
Authors: Barbara B.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Strategies Toward N‐Functionalized Cyclens
Authors: Suchy Mojmir , Hudson Robert H. E.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aliphatic and Alicyclic Aldehydes: Synthesis by Diels—Alder Reactions with Enals or Their Acetals
Authors: Witulski B. , Alayrac C.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Progress on Design and Synthesis of Photoactive Porphyrins‐based Dyads, Triads and Polymers
Authors: Jiang Li , Li Yuliang
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Heck‐Type Reactions with a Migrating Double Bond
Authors: Dyker Gerald
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1,3‐Dithietanes
Authors: Luh T.‐Y. , Leung M.‐k.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solid State Nuclear Magnetic Resonance Studies of Nanocarbons
Authors: Panich A. M.
Published: December 2008

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Magnetic labeling of non‐phagocytic adherent cells with iron oxide nanoparticles: a comprehensive study
Authors: Boutry Sébastien , Brunin Stéphanie , Mahieu Isabelle , Laurent Sophie , Elst Luce Vander , Muller Robert N.
Published: December 2008

Small particles of iron oxide (SPIO) and ultrasmall particles of iron oxide (USPIO), inducing a strong negative contrast on T2 and T2*‐weighted MR images, are the most commonly used systems for the magnetic labeling of cultured cells and their subsequent detection by magnetic resonance imaging (MRI). The purpose of this work is to study the influence of iron incubation concentration, nanoparticle size and nanoparticle coating on the magnetic labeling and the viability of non‐phagocytic adherent cells in culture. The magnetic labeling of 3T6 fibroblasts was studied by T2‐weighted MRI at 4.7 T and by dosing—or cytochemical revealing—of iron through methods based on Perl's Prussian blue staining. Cells were incubated for 48 h with increasing iron concentrations of SPIO (25–1000 µg Fe/ml Endorem®). Sinerem®, a USPIO (20–40 nm) coated with neutral dextran, and Resovist® (65 nm), a SPIO bearing an anionic carboxydextran coating, were compared with Endorem® (dextran‐coated, 80–150 nm) as magnetic tags. The iron loading of marrow stromal cell primary cultures (MSCs) isolated from rat femurs was compared with that of 3T6 fibroblasts. The SPIO‐labeling of cells with Endorem® was found to be dependent on the iron incubation concentration. MSCs, more sparsely distributed in the culture, exhibited higher iron contents than more densely populated 3T6 fibroblast cultures. A larger iron loading was achieved with Resovist® than with Endorem®, which in turn was more efficient than Sinerem® as a magnetic tag. The magnetic labeling of cultured non‐phagocytic adherent cells with iron oxide nanoparticles was thus found to be dependent on the relative concentration of the magnetic tag and of the cells in culture, on the nanoparticle size, and on the coating type. The viability of cells, estimated by methods assessing cell membrane permeability, was not affected by magnetic labeling in the conditions used in this work. Copyright © 2008 John Wiley & Sons, Ltd.
Surface Viscoelasticity of Concentrated Salt Solutions: Specific Ion Effects
Authors: Safouane Mahassine , Langevin Dominique
Published: December 2008

Herein, we study the viscoelastic response of concentrated salt solutions using surface waves excited by electrocapillarity. We show that the hydrodynamic behaviour of the solutions is similar to that of water at concentrations up to 2 m—well above the concentration C*, at which inhibition of bubble coalescence occurs in these solutions. This result excludes the occurrence of changes in the slip conditions at C*, postulated to explain this inhibition. Our study is carried out on salts that both increase and decrease the surface tension. We observe that the salt that decreases the tension does not change the surface behaviour at all, whereas the other two salts essentially produce negative contributions to the surface viscoelasticity at very high salt concentrations. The effects observed are quite large and remain to be explained.
Problems in the growth of Ce3+‐doped Li6Gd(BO3)3 crystals by Czochralski method
Authors: Yang F. , Pan S. K. , Ding D. Z. , Ren G. H.
Published: December 2008

Cerium‐doped lithium gadolinium borate (Li6Gd(BO3)3:Ce) single crystal has been grown by the Czochralski method. Some problems like macro defects and concave growth face were found. The macro defects are suggested to be caused by constitutional supercooling and concave growth face is caused by interface inversion. These problems can be resolved or eliminated through controlling the growth parameters strictly. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Ni1‐xCrx alloy for self controlled magnetic hyperthermia
Authors: Akin Y. , Obaidat I. M. , Issa B. , Haik Y.
Published: December 2008

It is known now that an increase in tumor temperature decreases the tumor resistance to chemo‐ and radiation therapies. Hyperthermia treatment of the tumor cells where damage to the healthy cells can be avoided is viable by using magnetic nanoparticles with controlled Curie temperatures. Nickel‐Chromium (Ni1‐x Crx) particles with varying compositions have been investigated as thermoseeds for use in localized self controlled hyperthermia treatment of cancer. A series of Ni1‐x Crx alloys, have been prepared to find the specific composition which has Curie temperature around 316‐317 K. The samples were cast by arc melting technique, and were annealed at 850 oC for 5 hours in sealed quartz tubes. Magnetic properties of the samples were investigated, including Curie temperature, saturation magnetization and hysterisis using Superconducting Quantum Interference Device (SQUID) and Vibrating Sample Magnetometer (VSM). The Curie temperatures of the alloys were found to decrease almost linearly from 401 K to 289 K as the Cr concentration was increased from x = 4.54 wt% to x = 5.90 wt%. The results showed that Ni1‐x Crx alloys might be good candidates for self regulating magnetic hyperthermia applications. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
New developments in small molecules targeting p53 pathways in anticancer therapy
Authors: Cheok Chit Fang , Lane David P.
Published: December 2008

The tumor suppressor p53 is frequently inactivated in a wide variety of cancers and point mutations or deletions of the p53 gene are associated with poor prognosis in cancer. About half of all human tumors carry wildtype p53 but p53 wildtype functions are often suppressed by the overexpression of murine double minute 2 (MDM2), a negative regulator of p53. Restoration of p53 functions in tumor cells, therefore, represents an attractive strategy in combating cancer and has been the focus of intensive anticancer drug discovery. One strategy is to antagonize MDM2 functions and initial success was demonstrated in vitro and in xenograft tumor models using newly discovered small molecule inhibitors and antisense oligonucleotides. The new discovery of a compound targeting SirT1 (a member of the sirtuin family) in a p53‐dependent reporter screen highlighted the importance of another negative regulator of p53 and offers an additional avenue for drug discovery and research on p53‐activating therapeutics. Here, we discuss the developments of p53‐activating small molecules and their potential use in combination therapy with established chemotherapeutics. These small molecules were discovered from chemical library screening using biochemical assays or cellular‐based assays, and/or structure‐based rational drug design strategies. Drug Dev Res 69:289–296, 2008. © 2008 Wiley‐Liss, Inc.
Carbonic anhydrase inhibitors: possible anticancer drugs with a novel mechanism of action
Authors: Supuran Claudiu T.
Published: December 2008

The tumor‐associated carbonic anhydrase (CA, EC 4.2.1.1) isozyme CA IX is highly overexpressed in many cancer types via the hypoxia inducible factor‐1α (HIF‐1α) cascade. Hypoxic tumors expressing CA IX show a poor response to classical chemo‐ and radio‐therapy treatments. CA IX significantly contributes to acidification of the tumor environment, by catalyzing the hydration of carbon dioxide to bicarbonate and protons with its extracellularly situated active site. This leads to the acquisition of metastasic phenotypes and chemoresistance to many anticancer drugs. Inhibition of CA IX by specific and potent sulfonamide inhibitors can reverse tumor acidification thus establishing a clear‐cut role of CA IX in tumorigenesis. The development of a wide range of such inhibitors belonging to diverse chemical classes (sulfonamides, sulfamates, sulfamides), such as membrane‐impermeant, fluorescent or metal‐containing compounds, provides useful tools for highlighting the exact role of CA IX in hypoxic cancers, to control the pH (im)balance of tumor cells, and to develop novel diagnostic or therapeutic approaches to manage tumor growth. Drug Dev Res 69:297–303, 2008. © 2008 Wiley‐Liss, Inc.
Colchicine site inhibitors of microtubule integrity as vascular disrupting agents
Authors: Lee Ray M. , Gewirtz David A.
Published: December 2008

Drugs that bind to the colchicine binding site of tubulin and induce tubulin depolymerization hold promise as antitumor drugs through their ability to induce cell cycle arrest and to kill cancer cells through apoptosis and mitotic catastrophe. However, development of this group of compounds as direct antitumor cytotoxic agents has not proved successful. Over the last few years, the potential of these compounds to act as selective vascular disrupting agents has been recognized. Several agents have advanced to phase I and phase II clinical studies, and their capacity to suppress growth of the tumor vasculature has been confirmed. Toxicity in terms of cardiovascular and thromboembolic events remains a major concern and their therapeutic efficacy as single agents has been disappointing. Nevertheless, a more comprehensive understanding of tumor compensatory mechanisms and potential combination strategies with anti‐angiogenic agents suggest that vascular targeting therapy may be a fruitful direction for the further development of this class of drugs as anticancer agents. Drug Dev Res 69:352–358, 2008. © 2008 Wiley‐Liss, Inc.
Summary of ‘Antibiotics to reduce post‐tonsillectomy morbidity’
Authors: Dhiwakar M. , Clement W. A. , Supriya M. , McKerrow W. S.
Published: December 2008

This is a summary of a Cochrane review, published in this issue of EBCH, first published as: Dhiwakar M, Clement WA, Supriya M, McKerrow WS. Antibiotics to reduce post‐tonsillectomy morbidity. Cochrane Database of Systematic Reviews 2008, Issue 2. Art. No.: CD005607. DOI: 10.1002/14651858.CD005607.pub2.

Further information for this Cochrane review is available in this issue of EBCH in the accompanying Commentary and Characteristics and Key Findings Tables. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Commentary on ‘Interventions for the interruption or reduction of the spread of respiratory viruses’
Authors: Gubbay J. B. , Matlow A. G.
Published: December 2008

This is a commentary on a Cochrane review, published in this issue of EBCH, first published as: Jefferson T, Foxlee R, Del Mar C, Dooley L, Ferroni E, Hewak B, Prabhala A, Nair S, Rivetti A. Interventions for the interruption or reduction of the spread of respiratory viruses.Cochrane Database of Systematic Reviews2007, Issue 4. Art. No.: CD006207. DOI: 10.1002/14651858.CD006207.pub2.

Further information for thisCochrane reviewis available in this issue of EBCH in the accompanyingEBCH SummaryandCharacteristics and Key Findings Tables. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Characteristics and key findings for ‘Corticosteroids for the prevention and treatment of post‐extubation stridor in neonates, children and adults’
Authors: van Dalen E. C. , Offringa M.
Published: December 2008

These are the characteristics and key findings for a Cochrane review published in this issue of EBCH, first published as: Markovitz BP, Randolph AG, Khemani RG. Corticosteroids for the prevention and treatment of post‐extubation stridor in neonates, children and adults. Cochrane Database of Systematic Reviews 2008, Issue 2. Art. No.: CD001000. DOI: 10.1002/14651858.CD001000.pub2.

Further information for this Cochrane review is available in this issue of EBCH in the accompanying EBCH Commentary and Summary articles. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Summary of ‘Corticosteroids for the prevention and treatment of post‐extubation stridor in neonates, children and adults’
Authors: Milne Andrea
Published: December 2008

This is a summary of a Cochrane review, published in this issue of EBCH, first published as: Markovitz BP, Randolph AG, Khemani RG. Corticosteroids for the prevention and treatment of post‐extubation stridor in neonates, children and adults. Cochrane Database of Systematic Reviews 2008, Issue 2. Art. No. CD001000. DOI:10.1002/14651858.CD001000.pub2.

Further information for this Cochrane review is available in this issue of EBCH in the accompanying Commentary and Characteristics and Key Findings Tables. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
A simplified method for HPLC‐MS analysis of sterols in vegetable oil
Authors: Carretero Antonio Segura , Carrasco‐Pancorbo Alegría , Cortacero Sonia , Gori Alessandro , Cerretani Lorenzo , Fernández‐Gutiérrez Alberto
Published: December 2008

We have developed a liquid‐chromatographic method using atmospheric pressure chemical ionization (APCI)‐mass spectrometry (MS) detection in positive mode. This method was used to separate and identify 15 sterols and 2 dihydroxy triterpenes in saponified oils, enabling the analysis of these compounds directly from saponified samples without recourse to thin‐layer chromatography; this fact thus significantly simplifies the process. The analyses were made using a Waters Atlantis 5 µm dC18 150×2.1 mm column with a gradient of acetonitrile/water (0.01% acetic acid) at a flow rate of 0.5 mL/min and a column temperature of 30 °C. The quantification of several of these compounds in soybean oil, palm oil, seed oil, sunflower oil, olive‐pomace oil and virgin olive oil was carried out using their commercial standards, and the results were compared satisfactorily with the official method.