bluuebunny/crossref_metadata_2025 huggingface dataset:
Ultrasound blood flow characteristics changes in fetal umbilical artery thrombosis: A retrospective analysis
Authors: Hong Si-Jie , Hong Li-Wei , He Xiao-Qin , Zhong Xiao-Hong
Published: January 2024

BACKGROUND

Umbilical artery thrombosis (UAT) is extremely uncommon and leads to adverse perinatal outcomes. Hypercoagulation of blood in pregnant women is suspected to be an important risk for UAT. Ultrasound is an effective way to detect thrombosis. The mother can monitor her own fetal health using ultrasound, which enables her to take preventative action in case of emergency.

AIM

To investigate ultrasonic blood signal after UAT in the umbilical artery, and evaluate the relationship between hypercoagulability and UAT.

METHODS

We described a case of a newly formed UAT with markedly altered ultrasonic indices of umbilical artery blood flow, and retrospectively studied it with 18 UAT patients confirmed by histopathology from October 2019 and March 2023 in Xiamen Women and Children's Hospital. Patients’ information was collected from medical archives, including maternal clinical data, neonatal outcomes, pathological findings and ultrasonic indices of umbilical artery blood flow, such as systolic-diastolic duration ratio (S/D), resistance index (RI), pulsatility index (PI) and peak systolic velocity (PSV). Ultrasound and coagulation indices were analyzed with matched samples t -test and Wilcoxon rank sum test using the statistical packages in R (version 4.2.1) including car (version 3.1-0) and stats (version 4.2.1), and visualized by ggplot2 package (version 3.3.6).

RESULTS

A patient with normal findings in second and third-trimester routine ultrasound scan developed UAT with severe changes in ultrasonic indices of umbilical artery blood flow (within 2.5th of reference ranges) in a short period of time. Statistical analysis of umbilical artery blood flow ultrasound indices for 19 patients with UAT showed that the decrease in S/D, RI, and PI and increase of PSV during the disease process was greater than that of non-UAT. All 18 patients delivered in our hospital showed characteristic manifestations of UAT on histological examination after delivery, most of which (16/18) showed umbilical cord abnormalities, with 15 umbilical cord torsion and 1 pseudoknot. Coagulation parameters were not significantly changed in UAT patients compared with normal pregnancy women.

CONCLUSION

Significant changes in ultrasound indicators after UAT were demonstrated. PSV can play important roles in the diagnosis of UAT. Hypercoagulability alone is not sufficient for the occurrence of UAT.
Understandings of success for groups managing leisure facilities through Community Asset Transfers
Authors: Haw Stuart , Potrac Paul , Wharton Karl , Findlay-King Lindsay
Published: January 2024

Community Asset Transfer (CAT), where voluntary community groups form to manage local facilities in replacement for local authorities (LAs) has increased. This paper discusses how successful management of the facilities is understood. Factors for this success involve community capital and these capitals underpin understandings of successful CATs. The study reveals perspectives of successful CAT by examining qualitative case studies of two cases of CAT of leisure facilities. Both involve social enterprises forming to conduct the CAT. Interviews with local authority staff, board members, staff, and volunteers within the community organisations reveal the perspectives on successful CAT and what successful asset management involves. Two findings are explored; success concerning outcomes of CATs benefitting residents; and this not being understood across cases. The paper is useful for LAs responsible for CATs and for community organisations considering pursuing a CAT.
Evaluating the concept of political masculinity/ies: a simple idea or a case of too many ideas?
Authors: Hearn Jeff
Published: January 2024

This article critically interrogates and evaluates the concept of political masculinities as part of enhancing dialogue between political science and critical studies on men and masculinities. It discusses what counts as masculinity, what counts as political and how they connect. The connections are all too clear in mainstream politics, not only in populist, authoritarian, ethno-nationalist and militaristic politics but also in democratic, socialist and various activist politics. The evaluation of the concept of political masculinities is conducted by asking three main questions: how does the concept add to, complement or contradict existing and established external concepts and theories? How is the concept constructed internally, and with what structure, elements and interrelations? And how can the application of the concept be possibly extended into fields beyond those usually recognized and labelled explicitly as specifically political fields, including the politics of the everyday and the politics of multiple global crises?
Sobre la redundancia de "subir para arriba", "bajar para abajo", "salir para afuera" y "entrar para adentro"
Authors: Sanromán Vilas Begoña
Published: January 2024

En este artículo se establece una diferencia entre la redundancia como mera repetición (R1) y la redundancia como forma de concordancia léxica (R2) para analizar las expresiones subir para arriba, bajar para abajo, salir para (a)fuera y entrar para (a)dentro. Primero, se extraen las ocurrencias de estas expresiones de dos corpus y, a continuación, se clasifican teniendo en cuenta el componente del movimiento focalizado (Meta, Trayectoria, Vía o Dirección) y el tipo de redundancia (R1 o R2). En el análisis de la R2, se especifica qué matiz semántico aporta el adjunto preposicional, que deja de interpretarse como redundante (R1). Se examinan también las implicaciones teóricas que conlleva la distinción R1-R2; entre ellas, la gradación de las expresiones redundantes, la naturaleza del significado aportado, proposicional en la R2 y comunicativo en la R1, y la relación del significado proposicional con las propiedades aspectuales de los predicados verbales.
Análisis del vocativo en los diálogos literarios del siglo XIV: Estudio contrastivo del "Libro del Cauallero Zifar" y del "Libro de Buen Amor"
Authors: Jiménez Sánchez Daniel
Published: January 2024

El análisis del progresivo cambio sintáctico y pragmático en la narrativa es fundamental para comprender la constitución del español moderno que hablamos hoy. Concretamente, las secuencias de diálogo en las obras literarias son uno de los medios fundamentales para estudiar la oralidad pasada, pues pueden suponer, en ocasiones, una representación del habla coloquial. Este trabajo abarcará el estudio de uno de los más representativos fenómenos lingüísticos que forman parte del plano dialogal, el vocativo, tomando como objeto de estudio dos obras literarias del siglo XIV: Libro del Cauallero Zifar y El Libro de Buen Amor, ambas de reconocida importancia para la literatura española. En este trabajo se analizarán las funciones del vocativo a partir de su forma, pretendiendo así arrojar luz acerca del funcionamiento de las diferentes estrategias comunicativas de los interlocutores del diálogo y del comportamiento lingüístico de los personajes dentro de las obras literarias analizadas.
La traducción de la poesía femenina hispanoamericana en China: ¿quién y qué se traduce?
Authors: Zhimeng Bai , Castañar Rubio Guillem
Published: January 2024

Desde la Reforma y Apertura en 1978, la literatura hispanoamericana ha sido introducida a gran escala en China. Entre las obras literarias traducidas, la poesía femenina ocupa una posición de gran importancia. A partir del estudio de las antologías traducidas que incluyen composiciones de autoría femenina publicadas en China desde 1985 hasta la primera década del siglo xxi, este artículo se centra en dos elementos relacionados con dichas antologías: cuáles son los poemas seleccionados y traducidos, y quiénes son sus autoras. Se analizan, en concreto, cuatro cuestiones: las poetas que aparecen en la mayoría de las antologías; las poetas con más poemas seleccionados; la distribución diacrónica de las poetas, y su distribución geográfica. El objetivo de este estudio es sintetizar los criterios seguidos por los traductores en la recopilación de las antologías y deducir así los intereses principales en China en el ámbito de la poesía femenina hispanoamericana.
The people of Chernobyl: a community of loss in Svetlana Aleksievich’s Chernobyl Prayer
Authors: Parts Lyudmila
Published: January 2024

Svetlana Aleksievich conducted hundreds of interviews with those affected by the explosion at the Chernobyl Nuclear Power Plant in Ukraine and her native Belarus and assembled them in her 1997 novel Chernobyl Prayer. A Chronicle of the Future. Aleksievich, awarded the Nobel Prize in Literature in 2015, created a complex, polyphonic blend of oral history and literature and provided a fragmentated and diverse narrative of memory, trauma, and victimhood. The article examines Aleksievich’s rendition of the ways in which “the people of Chernobyl” convey their own understanding of this identity. The many voices of Aleksievich’s novel coalesce to speak for what Serguei Oushakine calls a community of loss. The article traces the articulation of their identity: from the frustrated search for appropriate discursive tools and points of reference, to the explicit sense of having formed a unique social entity, a community. This transition is also a progression, through the process of articulation and analysis, from a negative identity, defined by loss and a radical change in status, to one enhanced by philosophical and environmental awareness. This is also a shift from the mainstream Soviet worldview and identity to other more complex, albeit less comforting perspectives.
Curación de contenidos en las redes sociales de revistas de información y documentación de Iberoamérica
Authors: Cascón Katchadourian Jesús , Artigas Wileidys , Guallar Javier
Published: January 2024

Objetivos: El artículo tiene como objetivo analizar las características de la curación de contenidos que llevan a cabo las revistas científicas iberoamericanas de información y documentación en sus redes sociales.
 Metodología: Investigación descriptiva basada en la técnica del análisis de contenido de productos digitales, donde se presenta un enfoque tanto cuantitativo, acerca de la presencia de los elementos estudiados, como cualitativo, de análisis y de selección de buenas prácticas. Se han examinado todas las revistas iberoamericanas de la categoría Library and Information Science según SCImago Journal & Country Rank (SJR).
 Resultados: El 60 % de las revistas tienen perfiles en redes sociales, aunque solo el 55 % se encuentran activos, siendo su plataforma preferida Twitter. Predomina en sus publicaciones la curación de contenidos, presente en el 86 % de sus posts en 15 de los 18 perfiles analizados; a nivel temático, la mayoría de las publicaciones tratan del número actual (60,57 %); en cada perfil de red social suele predominar una técnica de curación por encima del resto, siendo la más utilizada 'Comentar' (en seis perfiles), seguidas por 'Extractar', 'Resumir' y 'Citar' (en cuatro). Se concluye que buena parte de las revistas Iberoamericanas de información y documentación poseen redes sociales y que en estas usan ampliamente técnicas de curación de contenido para difundir su producción académica.
Rellegir l’Espanya contemporània des de la contrarevolució
Authors: Rueda Pep
Published: January 2024

Ressenya de

Pedro Rújula, Religión, rey y patria: Los orígenes contrarrevolucionariosde la España contemporánea, 1793-1840, Madrid, Marcial Pons, 2023
La Primera República a Barcelona als ulls d’un republicà finisecular
Authors: Pocino Àlex
Published: January 2024

Ressenya de 

Miquel González i Sugranyes, La República a Barcelona, 1873-1874,edició i estudi introductori de Jordi Roca Vernet i presentació de documentsi biografies de Ginés Puente, Barcelona, Ajuntament de Barcelona,2023, 429 p.
¿Son los hablantes de Madrid incapaces de distinguir la oposición CASA–CAZA reintroducida en Andalucía? Test de percepción intercomunitario
Authors: Molina García Álvaro
Published: January 2024

En el presente trabajo, incorporamos la percepción intercomunitaria a los estudios de cambio fonético. Para ello, elaboramos un test de percepción con 48 jueces procedentes de Málaga y de Madrid, cuyo objetivo principal era la identificación de las series léxicas CASA–CAZA de un hablante malagueño que presenta una escasa distancia acústica, pero que es percibido sin dificultad en su comunidad. Los resultados prueban que un mismo hablante es percibido como distinguidor dentro de su comunidad, pero como no distinguidor fuera de la misma, con un promedio de error del 36 %. El análisis acústico de los pares mínimos revela que la distancia acústica no es el parámetro que mejor explica la presencia de errores, sino que la posición que ocupan en el plano fónico funciona como un indicador más fiable.
The long-term average spectrum in forensic phonetics: From collation to discrimination of speakers
Authors: Just Alcaraz Jordi
Published: January 2024

The present work aims to provide more data regarding the comparison and discrimination of speech samples in the field of forensic phonetics. The methodology used was an acoustic method called long-term average spectrum (LTAS), by calculating its spectral decline. The informants were grouped into a total of four female speakers of the same age by close geographical origins. The extracted data were presented qualitatively and quantitatively. In view of the results, the identification of speakers was not successful in all cases. After discussing the results, implications for judicial phonetics and recommendations for future studies were collected.
The Family Protocol in Argentina. A Perspective from the Agency and Stewardship Theory and a Perception of Family Business Owners and Top Managers
Authors: Lucero Bringas María de los Ángeles , Caro Norma Patricia
Published: January 2024

This study seeks to examine the perspectives of family business owners and CEOs in Argentina on the necessary topics and elements to include in a family protocol that enhances family business continuity. Our model connects both Agency Theory and Stewardship Theory to the protocol with a focus on its impact on continuity. Data was collected through a survey completed by 220 family businesses in Argentina. Structural Equation Modeling was utilized to verify the model.The survey respondents' perception indicates that a family protocol aids the continuation of a family enterprise when it includes norms that diminish agency issues and promote stewardship behavior. Board formation regulation and family-business relation management are norms that lead to reducing agency issues. Thus, it is regarded as an efficient mechanism to avert or resolve conflicts without detrimental effects. Elements that endorse stewardship conduct include those that facilitate the emergence of a shared perspective, sense of membership, values, principles, traditions, and culture concerning both the content and the process. Accordingly, the two theories would be complementary.
Sobre la noción de mímesis en la apuesta política y metodológica de Luce Irigaray
Authors: Ugalde Guajardo Andrea
Published: January 2024

En el entramado filosófico, psicoanalítico y lingüístico del proyecto de Luce Irigaray la noción de mímesis guarda un lugar fundamental. Exhibido por la autora como recurso metodológico de investigación y como praxis política, es una estrategia que busca dislocar el orden discursivo que sostiene nuestra cultura occidental, eminentemente falogocéntrica y patriarcal. Este antídoto contra la uniformidad y la lógica original-copia que rige nuestra tradición es desplegado en su obra en virtud de tres dimensiones (Schor, 1993): la mascarada, la mímesis astuta y la reapropiación gozosa o diferencia positiva. En este texto, y articulando estos tres sentidos, me interesa trazar la cartografía de esta noción en virtud de algunos momentos del proyecto irigariano, atendiendo a sus aspectos genealógicos, éticos y políticos. La apuesta de Irigaray por el sentido transformador y creativo del recurso de la mímesis, en contraposición al sentido de imitación especular que atraviesa nuestra tradición de un solo sujeto, refleja la doble tarea de su cometido: la crítica profunda a las bases de la tradición del pensamiento occidental y la necesidad de generar las condiciones para transformar toda una cultura.
An Interview with Marsha Meskimmon
Authors: Pérez Fernández Andrea
Published: January 2024

An Interview with Marsha Meskimmon
Traducciones de la hospitalidad: la hauntología negra en «Candyman» (Nia DaCosta, 2021)
Authors: Molines Galarza Núria , Rodríguez Serrano Aarón
Published: January 2024

Este trabajo plantea una lectura de la película Candyman (Nia DaCosta, 2021) en el contexto de las aportaciones de las mujeres afroamericanas a las traducciones de la hospitalidad derridiana. Para ahondar en el funcionamiento de esa traducción, vincularemos dicho concepto con el pensamiento hauntológico, en especial, con la actualización de los postulados de la propuesta derridiana: la hauntología negra. Con este marco y una metodología de análisis fílmico narratológico centrado en los procesos de significación formal, se explora la transformación de DaCosta del concepto de hospitalidad. Tras el análisis, se concluye que la cineasta, con su reescritura narrativa, el tratamiento espacial y su visibilización autoral mediante la forma fílmica, genera un marco de exorcismo que reconceptualiza la hospitalidad y da voz a los espectros de las violencias sufridas por las comunidades afroamericanas estadounidenses.
Decolonial Phenomenologies: The Languages and Affect of In-Betweenness in Gloria E. Anzaldúa and Josefina Báez’s Early Work
Authors: Lara Bonilla Inmaculada
Published: January 2024

This article explores the intersections between Gloria Anzaldúa’s and Josefina Báez’s textual theories of in- betweenness, as they pertain to issues of textuality, and more broadly relationality, in their early work. In her life-long philosophical search Anzaldúa devised a phenomenology in which the metaphors of the border, borderlands, or bridges, and the concept of nepantla signal the place of writing in the context of coloniality, decoloniality, and migration. From her early thought, these concepts often capture not only issues of location, but also of intentionality and decolonial change. Similarly, Dominican American (DominicanYork) author, director, and performer Josefina Báez, explores the unstable spaces and temporariness of in-betweenness in the context of im/migration and colonization centering the experience of Dominican diasporic communities. Báez proposes concepts such as dominicanish or ‘bliss’ as imagined, relational spaces and states that are non-territorial, fleeting, and that resist the fixity of oppressive categorizations of the subject. Both authors are interested in finding the poetics that may be appropriate for such transfrontera spaces and states, as well as in theorizing new practices of reading (or viewing) and writing from these spaces. This paper describes these theories and shows how, by presenting readers with textual encounters in which the I must enter the unstable, hardly meltable, spaces in Borderlands/La Frontera: The New Mestiza (1987) and Dominicanish (2000), where the authors, as textual hosts, invite audiences to engage in a phenomenology of shifting where unsettling experiences of in-betweenness and impermanence may result in decolonial transformation.
Frequency properties of channeled spectropolarimetry: an information theory perspective
Authors: Hu Jing , Chen Xiuguo , Chen Wenlong , Yang Shilong , Wang Yifu , Tang Zirong , Liu Shiyuan
Published: January 2024

Channeled spectropolarimetry (CSP) has emerged as a notable technique due to its unique capacity to instantaneously measure either the polarization state of light or the Mueller matrix of a sample over a broad spectral range. Leveraging the quasi-linear relation between phase retardances of thick birefringent retarders and wavenumber, the target signal undergoes wavelength encoding. For the first time, we present a theoretical framework for the general CSP from a perspective of information theory. This framework comprehensively addresses the frequency properties of CSP, encompassing signal bandwidth, modulation frequency, sampling relationships, and filter window width during the demodulation process. Drawing from the frequency properties of CSP, we establish a theoretical foundation that informs the design of versatile CSPs and evaluates their measurement capabilities. Simulations for both Stokes CSP and Mueller CSP validate the efficacy of the proposed approach.
pH-responsive hydrogels embedded in hollow-core optical resonators
Authors: Loyez Médéric , Adolphson Maxwell , Liao Jie , Thakur Sanskar , Yang Lan
Published: January 2024

Whispering-gallery-mode (WGM) microresonators are typically studied for surface (bio)chemical sensing, mainly relying on small refractive index changes occurring within a nanometer range from their walls surface. This high sensitivity, reaching up to 10−5 refractive index unit (RIU, ∼2.5 nm/RIU and measured at a femtometer resolution) leads to broad ranges of applications, especially for biosensing purposes through the monitoring of molecular binding events. In this article, we investigate the gelling of thin layers of poly(vinyl alcohol)/poly(acrylic acid) (PVA/PAA) hydrogels inside a WGM microbubble resonator (MBR), fabricated from a silica capillary. The formation of such layers is achieved by withdrawing a liquid solution of 25% PVA/PAA in pure water into the MBR and locally heating the microbubble region, leading to hydrogel formation only in the WGM cavity. The capillary is then rinsed and tested under varying pH solutions. The swelling ability of these hydrogels is proportional to the pH of samples brought into contact with the cavity, leading to physical deformations of the layers consequently leading to changes in the WGM resonance condition. We show the preliminary results obtained for the gelling and characterization of these thin layers in microbubble resonators and present the related wavelength shifts observed for several pH values. We discuss the kinetics and practical uses, such as reversibility and tunable detection of small pH changes.
Researching COVID to enhance recovery (RECOVER) tissue pathology study protocol: Rationale, objectives, and design
Authors: Troxel Andrea B. , Bind Marie-Abele C. , Flotte Thomas J. , Cordon-Cardo Carlos , Decker Lauren A. , Finn Aloke V. , Padera Robert F. , Reichard R. Ross , Stone James R. , Adolphi Natalie L. , Casimero Faye Victoria C. , Crary John F. , Elifritz Jamie , Faustin Arline , Ghosh Saikat Kumar B. , Krausert Amanda , Martinez-Lage Maria , Melamed Jonathan , Mitchell Roger A. , Sampson Barbara A. , Seifert Alan C. , Simsir Aylin , Adams Cheryle , Haasnoot Stephanie , Hafner Stephanie , Siciliano Michelle A. , Vallejos Brittany B. , Del Boccio Phoebe , Lamendola-Essel Michelle F. , Young Chloe E. , Kewlani Deepshikha , Akinbo Precious A. , Parent Brendan , Chung Alicia , Cato Teresa C. , Mudumbi Praveen C. , Esquenazi-Karonika Shari , Wood Marion J. , Chan James , Monteiro Jonathan , Shinnick Daniel J. , Thaweethai Tanayott , Nguyen Amber N. , Fitzgerald Megan L. , Perlowski Alice A. , Stiles Lauren E. , Paskett Moira L. , Katz Stuart D. , Foulkes Andrea S. ,   on behalf of the RECOVER Initiative Autopsy Group
Published: January 2024

Importance

SARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or organ dysfunction after the acute phase of infection, termed Post-Acute Sequelae of SARS-CoV-2 (PASC), or long COVID. The characteristics, prevalence, trajectory and mechanisms of PASC are poorly understood. The objectives of the Researching COVID to Enhance Recovery (RECOVER) tissue pathology study (RECOVER-Pathology) are to: (1) characterize prevalence and types of organ injury/disease and pathology occurring with PASC; (2) characterize the association of pathologic findings with clinical and other characteristics; (3) define the pathophysiology and mechanisms of PASC, and possible mediation via viral persistence; and (4) establish a post-mortem tissue biobank and post-mortem brain imaging biorepository.

Methods

RECOVER-Pathology is a cross-sectional study of decedents dying at least 15 days following initial SARS-CoV-2 infection. Eligible decedents must meet WHO criteria for suspected, probable, or confirmed infection and must be aged 18 years or more at the time of death. Enrollment occurs at 7 sites in four U.S. states and Washington, DC. Comprehensive autopsies are conducted according to a standardized protocol within 24 hours of death; tissue samples are sent to the PASC Biorepository for later analyses. Data on clinical history are collected from the medical records and/or next of kin. The primary study outcomes include an array of pathologic features organized by organ system. Causal inference methods will be employed to investigate associations between risk factors and pathologic outcomes.

Discussion

RECOVER-Pathology is the largest autopsy study addressing PASC among US adults. Results of this study are intended to elucidate mechanisms of organ injury and disease and enhance our understanding of the pathophysiology of PASC.
Trumpism, climate and COVID: Social bases of the new science rejection
Authors: Hamilton Lawrence C.
Published: January 2024

Although the hazards posed by greenhouse warming and COVID-19 are quite different, diagnosis and mitigation prospects for both depend heavily on science. Unfortunately, the reality of both threats has been subject to politicized science rejection in the US, making these deadly problems less tractable. There are substantial parallels between the two cases of science rejection, including common rhetoric and conservative political leadership. Survey research has reached widely-replicated conclusions regarding the social bases of climate-change perceptions. Corresponding studies of COVID-19 perceptions have found some political commonalities, but less agreement on other details. Here, we address this gap using generalized structural equation modeling (GSEM) and 2021 US survey data to make direct comparisons between the social bases of rejecting the reality of anthropogenic climate change (ACC) and rejecting COVID-19 vaccination. Trumpism, operationalized from approval of ex-president Trump, is viewed as an intervening variable that influences both types of science rejection. Trumpism itself is predicted by age, race, evangelical religion, ideology, and receptivity to seemingly non-political conspiracy beliefs. Considering direct as well as indirect effects (through Trumpism), climate change and vaccine rejection are similarly predicted by white and evangelical identity, conspiracism, and by education×ideology and friends×party interactions. The finding that Trumpism exacerbates science rejection could also apply to other science- and expertise-related topics unrelated to climate and COVID. These results invite broader comparisons across topics, with analogous movements in other countries, and continued tracking as US Trumpism evolves beyond Trump.
Molecular basis of the reaction mechanism of the methyltransferase HENMT1
Authors: Kaldis Philipp , Zhao Li Na
Published: January 2024

PIWI-interacting RNAs (piRNAs) are important for ensuring the integrity of the germline. 3’-terminal 2’-O-methylation is essential for piRNA maturation and to protect them from degradation. HENMT1 (HEN Methyltransferase 1) carries out the 2’-O-methylation, which is of key importance for piRNA stability and functionality. However, neither the structure nor the catalytic mechanism of mammalian HENMT1 have been studied. We have constructed a catalytic-competent HENMT1 complex using computational approaches, in which Mg2+ is primarily coordinated by four evolutionary conserved residues, and is further auxiliary coordinated by the 3’-O and 2’-O on the 3’-terminal nucleotide of the piRNA. Our study suggests that metal has limited effects on substrate and cofactor binding but is essential for catalysis. The reaction consists of deprotonation of the 2’-OH to 2’-O and a methyl transfer from SAM to the 2’-O. The methyl transfer is spontaneous and fast. Our in-depth analysis suggests that the 2’-OH may be deprotonated before entering the active site or it may be partially deprotonated at the active site by His800 and Asp859, which are in a special alignment that facilitates the proton transfer out of the active site. Furthermore, we have developed a detailed potential reaction scenario indicating that HENMT1 is Mg2+ utilizing but is not a Mg2+ dependent enzyme.
Prevalence of childfree adults before and after Dobbs v Jackson in Michigan (USA)
Authors: Neal Jennifer Watling , Neal Zachary P.
Published: January 2024

Childfree adults are the most common type of non-parent in the United States and are distinguished by their lack of desire to have children. Although there are many reasons one may choose not to have children, recent restrictions on reproductive health care may also contribute to this decision. For example, the United States Supreme Court’s decision in Dobbs v. Jackson eliminated a long-standing constitutional protection for abortion access, which reduced patients’ medical autonomy and increased the risks of pregnancy and childbirth, and therefore may have led adults to decide not to have children. In this study, we use representative data on Michigan adults immediately before and after the Dobbs decision to examine changes in the prevalence of childfree adults in this population. We find that 21% of Michigan adults were childfree before the Dobbs decision, but this number rose to nearly 26% after the decision. Controlling for demographic characteristics, a Michigan adult was 32.8% more likely to be childfree after the Dobbs decision than before. We conclude that when access to safe reproductive health care is uncertain or unavailable, adults that do not already have children may decide that they do not want children.
Treating social cognition impairment with the online therapy ’SoCoBo’: A randomized controlled trial including traumatic brain injury patients
Authors: Lohaus Tobias , Reckelkamm Sally , Thoma Patrizia
Published: January 2024

Objective

Acquired brain injuries (ABIs), such as traumatic brain injuries (TBIs), often entail impairments of general cognition (e.g., memory, attention or executive functions) and social cognition (e.g. emotion recognition, theory of mind [ToM], social problem-solving). The availability of fully computerized interventions targeting sociocognitive deficits specifically in neurologically impaired patients is extremely limited. Therefore, the Treatment Program for Deficits in Social Cognition and Social Competencies of the Ruhr University Bochum (SoCoBo), a fully computerized online therapy designed for ABI patients was evaluated in a randomized controlled trial involving TBI patients.

Method

Sixty-four patients with TBI were randomly assigned to two groups with 43 patients fully completing either SoCoBo (N = 27) or a commercially available computerized program for cognitive rehabilitation (RehaCom®, N = 16). All participants underwent comprehensive pre-post online neuropsychological assessment and worked with their respective rehabilitation programs for four days a week during a scheduled period of 12 weeks.

Results

After treatment, the SoCoBo group, but not the RehaCom® group showed significant improvements in facial emotion recognition and self-rated empathy. Moreover, in the SoCoBo group, an increase in empathy was also associated with increased life satisfaction after treatment. There were no improvements in ToM and social problem-solving. Furthermore, general cognition did not improve in any of the groups.

Conclusions

SoCoBo represents an effective new online therapy for the amelioration of deficits in key domains of social cognition. Its implementation in clinical practice will serve as a meaningful addition to the existing fully computerized approaches specifically in neurological patient groups.
The relationship of within-individual and between-individual variation in mental health with bodyweight: An exploratory longitudinal study
Authors: Mueller Julia , Ahern Amy L. , Jones Rebecca A. , Sharp Stephen J. , Davies Alan , Zuckerman Arabella , Perry Benjamin I. , Khandaker Golam M. , Rolfe Emanuella De Lucia , Wareham Nick J. , Rennie Kirsten L.
Published: January 2024

Background

Poor mental health is associated with obesity, but existing studies are either cross-sectional or have long time periods between measurements of mental health and weight. It is, therefore, unclear how small fluctuations in mental wellbeing within individuals predict bodyweight over short time periods, e.g. within the next month. Studying this could identify modifiable determinants of weight changes and highlight opportunities for early intervention.

Methods

2,133 UK adults from a population-based cohort completed monthly mental health and weight measurements using a mobile app over a period of 6–9 months. We used random intercept regression models to examine longitudinal associations of depressive symptoms, anxiety symptoms and stress with subsequent weight. In sub-group analyses, we included interaction terms of mental health variables with baseline characteristics. Mental health variables were split into “between-individual” measurements (= the participant’s median score across all timepoints) and “within-individual” measurements (at each timepoint, the difference between the participant’s current score and their median).

Results

Within-individual variation in depressive symptoms predicted subsequent weight (0.045kg per unit of depressive symptom severity, 95% CI 0.021–0.069). We found evidence of a moderation effect of baseline BMI on the association between within-individual fluctuation in depressive symptoms and subsequent weight: The association was only apparent in those with overweight/obesity, and it was stronger in those with obesity than those with overweight (BMI<25kg/m2: 0.011kg per unit of depressive symptom severity [95% CI -0.017 to 0.039]; BMI 25–29.9kg/m2: 0.052kg per unit of depressive symptom severity [95%CI 0.010–0.094kg]; BMI≥30kg/m2: 0.071kg per unit of depressive symptom severity [95%CI 0.013–0.129kg]). We found no evidence for other interactions, associations of stress and anxiety with weight, or for a reverse direction of association.

Conclusion

In this exploratory study, individuals with overweight or obesity were more vulnerable to weight gain following higher-than-usual (for that individual) depressive symptoms than individuals with a BMI<25kg/m2.
A bottom-up approach dramatically increases the predictability of body mass from personality traits
Authors: Arumäe Kadri , Vainik Uku , Mõttus René
Published: January 2024

Personality traits consistently relate to and allow predicting body mass index (BMI), but these associations may not be adequately captured with existing inventories’ domains or facets. Here, we aimed to test the limits of how accurately BMI can be predicted from and described with personality traits. We used three large datasets (combined N ≈ 100,000) with nearly 700 personality assessment items to (a) empirically identify clusters of personality traits linked to BMI and (b) identify relatively small sets of items that predict BMI as accurately as possible. Factor analysis revealed 14 trait clusters showing well-established personality trait–BMI associations (disorganization, anger) and lesser-known or novel ones (altruism, obedience). Most of items’ predictive accuracy (up to r = .24 here but plausibly much higher) was captured by relatively few items. Brief scales that predict BMI have potential clinical applications—for instance, screening for risk of excessive weight gain or related complications.
Subsídios para a estruturação da história dos acontecimentos ocorridos no distrito do Congo (Uíge) - Volume II: Intendente Custódio Ramos Para O Ministério do Ultramar
Authors: Ramos Custódio
Published: January 2024

Em Março de 1961 Custódio Abel Fernandes Ramos – administrador do concelho de Carmona (Uíge) – testemunhou no terreno o início da luta armada pela independência de Angola. Incumbido de narrar os acontecimentos pelo então Ministro do Ultramar, Adriano Moreira, Custódio Ramos produziu um minucioso relatório constituído por mais de mil páginas de informação sobre os primeiros meses da insurreição nacionalista promovida pela União dos Povos de Angola (UPA) no Noroeste de Angola. Nesse relatório, Custódio Ramos não só documentou com grande diligência os factos relativos à eclosão da luta armada, mas procurou também interpretá-los em termos político-ideológicos, no contexto da Guerra Fria, utilizando para o efeito os métodos analíticos e discursivos próprios do Estado Novo. Neste sentido, o relatório, ora publicado em edição fac-similada, constitui uma fonte documental preciosa e extremamente relevante não só para a reconstituição dos factos históricos em si, mas também para a compreensão do pensamento e da reação da administração colonial portuguesa no primeiro ano de guerra em Angola.
Variación morfosintáctica en la condicionalidad (no)prototípica: la conjunción si como constructora de espacio mental
Authors: Serrano María José
Published: January 2024

La conjunción si está tradicionalmente relacionada con la construcción de las oraciones condicionales, también inscritas en el denominado periodo condicional o hipotético, aunque puede introducir enunciados de otro tipo. Mediante una variada combinación de tiempos verbales en ambas cláusulas, las oraciones condicionales manifiestan diversos grados de posibilidad o de cumplimiento de la condición, basados en la realidad manifestada. La variación morfosintáctica debe estudiarse desde una perspectiva isomórfica a partir de la cual todo cambio en la forma conlleva un cambio en el significado. Así pues, este trabajo investiga la variación en el uso de las distintas construcciones con si desde una perspectiva isomórfica en el marco teórico funcional-cognitivo, más concretamente sobre la base teórica de la construcción de espacios mentales. Partimos de la hipótesis de que la conjunción si construye un espacio mental concreto que crea un dominio cognitivo bajo el cual surgen diversos significados y valores que, al mismo tiempo, establecen un punto de vista discursivo. Para llevar a cabo la investigación se han utilizado los textos del Corpus de Referencia del Español Actual (CREA), de los cuales se han extraído 865 construcciones con si. Tales textos se clasifican en magazines, conversaciones espontáneas, entrevistas, documentales, emisiones deportivas, debates y noticias. El análisis será primordialmente cualitativo mediante el estudio discursivo-cognitivo de la conjunción si y de los elementos lingüísticos con los que coaparece, como los tiempos verbales. La cuantificación se ha realizado mediante el programa estadístico Rbrul (Johnson 2009), que proporciona los porcentajes de cada categoría analizada. Además, la división tradicional entre distintos tipos de construcciones condicionales se sustituye por la de condicionales prototípicas y no prototípicas, lo cual permite vislumbrar y determinar de forma más clara el valor de asertividad que construye si como espacio mental. Se concluye que las construcciones con si dan lugar a distintos significados. Debido a la ausencia estructural de apódosis en las no prototípicas, estas tienden a constituir recursos de cortesía en la interacción, por lo que los valores van encaminados a la expresión de variados matices, y buena parte de ellas constituyen estructuras ya gramaticalizadas.
Reseña del libro: Martín, Aníbal (2023). Yo hablo, ellas cantorin. Las aventuras de un extremeño por los caminos de la diversidad lingüística
Authors: Méndez Santos María del Carmen
Published: January 2024

Reseña del libro: Martín, Aníbal (2023). Yo hablo, ellas cantorin. Las aventuras de un extremeño por los caminos de la diversidad lingüística. Madrid: Pie de página, 274 páginas, ISBN 9788412715804.
Garcilaso y los escritores cortesanos: una aproximación sociológica al panorama poético en vulgar de la Nápoles de 1530
Authors: De la Torre Ávalos Gáldrick
Published: January 2024

Este capítulo se interesa por la figura del escritor cortesano y su relación con algunas de las características del panorama poético en vulgar de la Nápoles de 1530. A través del apoyo en documentos históricos y testimonios literarios, se pone de manifiesto la autoconciencia que tanto Garcilaso como los poetas de su entorno tenían de su propia identidad como escritores de corte, con el propósito, en última instancia, de alumbrar ciertos aspectos comunes en su poesía solo explicables a partir de su análoga participación dentro del mismo contexto sociológico. El estudio se enmarca en la realidad socioeconómica neofeudal del reino de Nápoles, que desde tiempos de Ferrante I asignó al escritor una función subalterna asumida especularmente en el ámbito de la corte nobiliaria, considerando a su vez elementos del panorama cultural, motivados por la presencia hispánica en el regno, que, a diferencia de otros territorios italianos, influiría en la caracterización caballeresca del escritor cortesano de la Nápoles virreinal.
Administração Pública: A Processualidade Administrativa e a Redução das Demandas Judiciais
Authors: Silva Bruno Cezar , Souza Maria Auxiliadora Alves de , Lima Mauricene de Paula
Published: January 2024

A concepção de processualidade administrativa como função da Administração Pública, consolida-se a partir da Constituição Federal, impondo limite ao poder estatal e garantindo aos cidadãos o direito de participação ativa nas decisões administrativas. O presente artigo tem por objetivo demonstrar, com base na revisão bibliográfica e na análise de registro de dados de acesso público, a importância da temática, como meio de redução das demandas judiciais em que a Administração Pública figure como parte processual e se isso contribui para o desafogamento do Poder Judiciário. Foram analisados dados registrados no site do Conselho Nacional de Justiça (CNJ), para verificar se há uma relação entre os registros e a atuação morosa e ilegítima, decorrente da ausência de boas práticas administrativas e inferiu-se que a Administração Pública figura como maiores litigantes nos últimos dez anos representando uma carga processual de mais da metade dos processos em trâmite nos tribunais do país.
Inclusão da Criança Autista no Âmbito Escolar
Authors: Vieira Laíza da Silva , Alves Francisca Ivoneide Benicio Malaquias , Bringel Maricélia Félix Andrade
Published: January 2024

O principal objetivo deste trabalho é descrever a inclusão da criança com Transtorno do Espectro autista na escola. É uma pesquisa qualitativa e de cunho bibliográfico que busca falar sobre o espectro autista, e de que forma pode acontecer a inclusão desses alunos no ambiente escolar. Para tal finalidade, o trabalho busca também ressaltar a importância da parceria família e escola, visto que é algo que requer uma observação por parte de pais e professores, para que juntos possam observar as dificuldades de alunos com TEA (transtorno do espectro autista) para facilitar o processo de identificação do transtorno, e obter um diagnóstico precoce para o processo de inserção desses alunos em sala de aula. Visto que o diagnóstico precoce ajuda no processo de inclusão, pois facilita que o professor, que é o principal sujeito nesse processo, consiga atender cada criança de acordo com suas especificidades, na busca de proporcionar uma melhor aprendizagem; É essencial um olhar mais atento por parte do docente voltado para essas crianças, pois cada aluno possui sua necessidade, e esse olhar faz com que de fato aconteça a inclusão.
Perilaku Sedentary pada Remaja Akhir Berdasarkan Banyaknya Akun Media Sosial yang Dimiliki
Authors: Etika Arif Nurma , Agnes Yeni Lufiana Novita , Yunalia Endang Mei , Prayogi Ines Septiya
Published: January 2024

Non-communicable diseases including cardiovascular disease, diabetes and cancer are the number 1 killers in the world. According to the Indonesian Ministry of Health, the incidence of non-communicable diseases in Indonesia increase every year. One of the main factors causing non-communicable diseases is sedentary lifestyle. Sedentary lifestyle are activities that all types of activities need very little caloric (< 1.5 METs). Currently, the use of social media among adolescents is massive. This study aims to identify sedentary behavior in late adolescents based on the amount of social media they have. This research was a correlational analytical research with a cross sectional approach. The sample were 193 students of the Faculty of Health in Kediri. The data were collected using snowball sampling. The instrument used in this study was a modified Sedentary Behaviour Questionary (SBQ). The data obtained were analyzed using the Spearman Rank Test. The results of this study showed that 49.7% performed high sedentary behavior. 42% of late adolescences have 4/more social media accounts, 90.7% of late adolescences use social media daily. The results of the Spearman rank test obtained p-value: 0.031 so there was a relationship between the amount of social media and sedentary behavior, and also p-value: 0.036, Correlation Coefficient: 0.615 so that there was a strong relationship between frequent use of social media with sedentary behavior. From the results of the study, it is recommended to reduce the intensity of social media, so that sedentary behavior can also be minimized, and prevent non-communicable diseases.
Hubungan Kemampuan Adaptasi Kerja dengan Penerapan Kesehatan dan Keselamatan Kerja Perawat
Authors: Astawa I Made Adi , Wati Ni Made Nopita , Wati Ketut Lisna
Published: January 2024

The Hospital occupational health and safety programs’ objectives to guarantee and protecting the nurses’ health and safety. However, nurses need to adapt regarding the working conditions to implement the nursing service optimally.   This study aims to identify the relationship between the nurses' working adaptability and the implementation of occupational health and safety among associate nurses.  This study was a quantitative study employed a cross-sectional design. The sampling technique employed in this study was purposive sampling with a sample size of 103  associate nurses choosen by using inclusion and exclusion criteria. The instruments employed to measure adaptability and application of occupational health and safety was questionnaires that has been tested for validity and reliability. This study has been ethically approved through ethical clearance number 070/5630/RSUDW.  The data analyzed employed in this study was Rank Spearman Correlation test. The study results found that the majority of nurses showed have a good working adaptability (86 peoples;83,5%), the occupational health and safety implementation (88 peoples, 85,4%) by p-value = 0.000; r = 0.780 which means there is a significant relationship between the nurses' working adaptability and the implementation of occupational health and safety with a strong positive relationship. Nurses are expected to implement occupational health and safety optimally in order to improve the quality of nursing care services delivered to patients.