bluuebunny/crossref_metadata_2025 huggingface dataset:
Benign Diseases Masquerading as Cholangiocarcinoma: Can we Differentiate before Surgery?
Authors: Wannasri Thitiporn , Luvira Vor , Wongwattanachai Arada , Titapun Attapol , Srisuk Tharatip , Kamsa-ard Supot , Tipwaratorn Theerawee , Theeragul Suapa , Pugkhem Ake , Jarearnrat Apiwat , Khuntikeo Narong , Pairojkul Chawalit , Bhudhisawasdi Vajarabhongsa
Published: December 2022

Background: Cholangiocarcinoma (CCA) is a potentially lethal disease that requires surgical treatment. There are many benign conditions, those that do not require surgical treatment, displaying imaging characteristics that resemble CCA, leading to therapeutic misadventures. This study aimed to evaluate the proportion of benign conditions that underwent hepatic resection for presumed CCA, and explore the differences between the characteristics of these two entities stratified by primary imaging features of the lesions. Methods: This retrospective study ran between January 2004 and December 2011. We reviewed the pathological records of all 1,402 patients who underwent curative-intent hepatic resection for preoperatively diagnosed CCA. All clinical and pathological parameters were analyzed. Results: The proportion of benign conditions that underwent hepatic resection was 3.78% (53/1,402). For mass-forming lesions, CCA was associated with higher age, alkaline phosphatase, tumor markers, neutrophil to lymphocyte ratio, and mass size. The patients with mass-forming benign conditions were more associated with diabetes mellitus. For lesions with bile duct dilatation, intraductal tumor, including CCA, had higher CA19-9 level and NLR with statistical significance. For cystic lesions, biliary cystic neoplasm had statistical significance in the rate of abdominal pain. Conclusions: The proportion of hepatic resection for benign conditions was quite low. There were many characteristic differences used to differentiate benign mass-forming conditions from CCA, whereas only few markers in the setting of cystic lesions and biliary dilatation. We recommend performing standard hepatic resection in every case, regardless of the type of imaging features, if the lesion has a chance of being CCA.
Predictors of Coping Strategies among Cervical Cancer Patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: A Cross-sectional Study
Authors: Dirar Anteneh , Mekonnen Wubegzier , Berhanu Zena
Published: December 2022

Background: The diagnosis and treatment of cervical cancer could result in psychological distress. Greater understanding of patients’ coping strategies, and influencing factors, can aid in developing appropriate psychosocial support. The aim of this study was to assess the prevalence of coping strategies and associated factors among cervical cancer patients. Materials and methods: A cross-sectional study was conducted among 299 cervical cancer patients on follow-up treatment at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Data were collected through face-to-face interview to assess patients’ sociodemographic characteristics, self-efficacy, meaning in life, perceived social support, uncertainty, cognitive appraisal, and coping strategies. Pearson’s correlation coefficient and linear regression analysis was conducted. Results: Findings reveal that women utilized both problem-focused and emotion-focused coping strategies. However, emotion-focused coping strategies were more frequently employed than problem-focused coping strategies by cervical cancer patients. Self-efficacy (ß=.27, p<.001), meaning in life-presence (ß= -.25, p=.015), perceived social support from friend (ß= .36, p<.001), and perceived social support from significant others (ß= -.27, p=.048) predicted emotion-focused coping strategies. Moreover, self-efficacy (ß=.25, p<.001), uncertainty (ß= -.13, p=.003), meaning in life-presence (ß= -.12, p=.003), meaning in life-search (ß= .12, p=.009), perceived social support from family (ß= .11, p=.021), and challenge appraisals (ß= .13, p=.010) were determinants of problem-focused coping strategies. Conclusion: This study demonstrates that women with cervical cancer adopt varied coping strategies to deal with their illness. Since coping strategies adopted are influenced by the extent of personal and environmental factors, there is a need to take these factors into account when developing tailored interventions to support patients’ coping strategies.
Knowledge and Experience of Women with Breast Cancer Receiving Chemotherapy in Selected Public Hospitals, Addis Ababa Ethiopia, 2021: Cross-sectional Study
Authors: Ayalew Kalkidan , Ayalew Yohannes , Alemu Tsion , Gebru Tilaye
Published: December 2022

Background: Breast cancer is the most common cancer in women worldwide, in 2018 2.1 million new cases are diagnosed. In Ethiopia due to the increasing awareness of breast cancer patients are taking chemotherapy in different parts of the country but patients’ knowledge of chemotherapy and experience of chemotherapy have not been assessed very well and this study tried to assess patients’ knowledge about chemotherapy. Objective: The objective of the study is to assess the knowledge and experience of women with breast cancer receiving chemotherapy in selected public hospitals in Addis Ababa Ethiopia, in 2021. Methods: Institutional based cross-sectional study was conducted and data was collected from Tikur Anbessa Specialised Hospital and Saint Paul Hospital Millennium Medical College from February 8 to March 1, 2020. Data was entered into Epi-data version 4.6.0 and exported to SPSS version 26. Descriptive statics such as frequency, percentages, mean and standard deviation were done and displayed in tables. Bivariate and multivariate logistic regression analysis was employed. Results: The study involved 250 participants. The mean age of the respondents was (43.35±11.1). Of the total 135 (54%) respondents were not knowledgeable and 115 (46%) were knowledgeable. Age >45 years and patients who lived in Addis Ababa were associated with higher knowledge. Respondents who took chemotherapy fourth to the sixth cycle and who are currently single were associated with the worst experience and the distance-time it takes to get to the hospital when is three to six hours were associated with the tolerable experience. Conclusion and recommendations: The study revealed that more than half of the participants were not knowledgeable and more than half of the participants had the worst experience. Hence healthcare providers should provide information about chemotherapy to their patients and should teach them how to manage the possible side effects.
Internet-Based Cognitive Behavioral Therapy for Depression and Anxiety Symptoms in Cancer: A Meta-Analysis
Authors: Cristina G. Domingo , Jessa Gilda P. Pandy , Marie Belle D. Francia
Published: December 2022

Background: Depression and anxiety affect up to 20% of patients with cancer. Physical treatment and side effects are usually the only factors given attention to during treatment and recovery. Psychological distress can have deleterious effects in their quality of life, and may even affect healing. Treatment options for depression and anxiety are limited. One well-studied treatment is cognitive behavioral therapy (CBT). However, face-to-face treatment has been a challenge for the oncology team during this pandemic. Internet-based cognitive behavioral therapy (iCBT) can be a new means of dealing with cancer patients’ psychological health. Objective: To evaluate iCBT in alleviating depression and anxiety symptoms in patients with cancer. Methods: A systematic search of Pubmed, Embase, Cochrane, Clinical trials databases and hand search were utilized to identify randomized controlled trials (RCTs) investigating the role of iCBT in addressing psychological distress in cancer patients. Meta-analysis was conducted on 4 randomized controlled trials (N=548). All 4 studies were included for analysis. Psychological distress was measured as depression and anxiety based on the Hospital Anxiety and Depression Scale (HADS) total scores. Results: There was a trend in improvement of anxiety and depression in the iCBT treatment group, however, it was not significant (p = 0.06). Due to substantial heterogeneity, subgroup analyses was done and showed improvement of anxiety and depression in patients with different cancer types and baseline psychological distress (p < 0.00001). Conclusion: The results indicate that iCBT can be a potential treatment option in cancer patients who exhibit baseline depression and anxiety, especially during this pandemic. More studies are needed to determine the efficacy of iCBT in cancer patients who are not clinically diagnosed with psychological disorders.
Immunohistochemical Detection of BRAFV600E in Cutaneous Melanocytic Neoplasms in a Cohort of Egyptian Population
Authors: M. Yakout Nada , M Abdallah Dina , A Abdelmonsif Doaa , Mahmoud  Kholosy Hassan , Elsakka Omayma
Published: December 2022

Objective: Melanocytic neoplasia shows different pathways that have been implicated in tumorigenesis. One of the key genes involved in the BRAFV600E gene, can be detected through DNA-based or protein-based tests including immunohistochemistry (IHC). To check its reproducibility, this study was conducted to evaluate BRAFV600E IHC by different observers in a range of melanocytic neoplasms. Methods: The present study was performed to evaluate immunohistochemical staining (IHC) using the RM-08 to detect BRAF V600E in 50 formalin-fixed paraffin-embedded (FFPE) blocks of different melanocytic neoplasms after bleaching using Tris-HCL buffer. IHC was considered positive when more than 90% of tumour cells showed cytoplasmic staining. IHC assessment by a team of two pathologists and a third pathologist to check the interobserver variability. IHC scores were compared among nevi and melanoma. Results: IHC evaluation revealed good agreement by different observers (ĸ-coefficient=0.691, p=0.00). BRAFV600E showed a statistically significant difference between nevi and melanoma. Conclusions: These findings suggest that BRAFV600E IHC assessment shows good reproducibility among pathologists, however, more strict criteria should be adopted in interpretation, especially in bleached samples.
Mor Pigmentli Meyve ve Sebzelerin Kanser İle İlişkisinin İncelenmesi
Authors: ÖNEÇ AYDIN Rahel , KÖSEOĞLU Sabiha Zeynep Aydenk
Published: December 2022

Kanser, dünya çapında ölüm nedeni yüksek olan önemli hastalıklardan biri olarak tanımlanmaktadır. Sebze ve meyveler içerisinde vitaminler, mineraller, folatlar, diyet lifleri ve çeşitli doğal biyoaktif bileşikler gibi faydalı besinleri içermektedir. Bunlar sayesinde birçok kanserin patolojik süreçleri önlenerek, kansere bağlı ölümlerin azaltıldığı görülmektedir. Spesifik olarak sebze ve meyvelerin kanser önleyici etkisi bulunmaktadır. Bunun nedeni ise içerisinde bulunan doğal biyoaktif bileşiklerdir. Bir çok biyoaktif bileşiğin pigmentlerle çok özel renklere sahip olduğu belirlenmiştir. Bunların insan vücudundaki etkisinin renklerine gör değiştiği görülmektedir. Kırmızı pigmentli gıdalar incelendiğinde bunların yararlı etkilerinin olduğu, bunların anti-tümör, anti-inflamatuar ve antioksidatif özelliklerinin incelendiği ortaya çıkmıştır. Kırmızı pigmentli gıdalarda bulunan biyoaktif bileşiklerin anti-kanser etkilerinin çoğu, kanser hücresi istilası ve metastazının baskılanmasının yanı sıra apoptoz ve hücre döngüsü durmasının indüklenmesinden kaynaklandığı görülmektedir. Bu derlemede; kırmızı-mor pigment içeren meyvelerin kanser ile ilişkisi incelenmektedir.
QuaVita: Sağlıklı Yaşam Mobil Uygulaması
Authors: GÜLER Osman , CAN Özgü
Published: December 2022

Mobil sağlık, kullanıcıların sağlıklarını takip etmelerini, tıbbi verilerini izlemelerini, tedavi süreçleri ile ilgili hatırlatma uyarılarını almalarını, günlük aktivitelerini ve yaşam biçimlerini izlemelerini sağlamaktadır. Günümüzde mobil cihaz kullanımı sağlıklı yaşam biçiminin sürdürülmesindeki en önemli araçlardan biri haline gelmiştir. Hayatımızın bir parçası haline gelmiş olan mobil cihazlar, mobil sağlık amacı ile kullanılmakta ve kullanıcıların sağlık durumlarını kolaylıkla takip edebilmelerini sağlamaktadır. Bu çalışmada, sağlıklı yaşam sürecinin izlenmesini sağlamak için QuaVita sağlıklı yaşam mobil uygulaması geliştirilmiştir. Geliştirilen QuaVita mobil uygulaması ile kullanıcıların sağlıklı bir yaşam süreçlerine destek olmak amaçlanmaktadır. QuaVita, kullanıcıların sağlık verilerini saklamalarını, kalp ritimlerini ölçebilmelerini, ilaç alarmı, günlük adım takibi ve su tüketim takibi yapabilmelerini sağlamaktadır. Kullanıcılar ayrıca, Türkiye’deki tüm nöbetçi eczanelere uygulama üzerinden erişebileceklerdir. QuaVita uygulaması ile her yaştan kullanıcının sağlıklı yaşam hedeflerini kolay bir şekilde takip edebilmeleri amaçlanmıştır. Böylelikle, kullanıcılar sağlıkları konusunda daha bilinçli olabilecekler ve sağlıklı yaşam biçimlerine yönelik farkındalıklarını arttırabileceklerdir.
Görüntüler İçin Kaotik Şifreleme Sistemi Ve Performans Analizi
Authors: SEVAL Gizem , KASAPBAŞI Mustafa Cem
Published: December 2022

Teknoloji yıllar içinde çok hızlı bir şekilde ilerlemiş ve bu ilerleyişine hızla devam etmektedir. Bu süreçte verilerin güvenliğini sağlama konusu da her alanda önemini arttırmıştır. Bu çalışmada kullanılan veri kaynağı görüntü olarak seçilmiştir. Görüntü şifrelemede histogram, korelasyon, diferansiyel saldırı, anahtar uzay, anahtar hassasiyet, zaman karmaşıklığı, entropi başarı analizleri ve istatiksel analizlere yönelik NIST testleri kullanılmıştır. Tanımlanan analiz ve testler doğrultusunda gerçekleştirilen analiz sonuçları karşılaştırılarak görüntü şifrelemede kullanılan bu yöntemlerin çıktı olarak doğru sonuçları ve beklenen performansları verip vermediği değerlendirilmiştir. Önerilen şifreleme yönteminin çıktı olarak başarılı sonuç ve performansları verdiği gözlemlenmiştir.
Applications of Artificial Intelligence in Mechanical Engineering
Authors: ARTKIN Ferit
Published: December 2022

Artificial intelligence (AI) technology, as one of the most sophisticated science and technology in today's world, is increasingly being used to production and life, particularly in the manufacturing business. it demonstrates how artificial intelligence technology is used in mechanical manufacturing, namely in defect detection, quality inspection, enhancing workplace safety, and other areas. Artificial intelligence technology is becoming increasingly important in people's lives as it becomes more widely used in people's daily lives, such as the widespread use of smart dishwashers and smart sweepers, which are the products of the fusion of artificial intelligence and the mechanical manufacturing industry. Indeed, artificial intelligence technology has been widely utilized in the mechanical manufacturing business, which not only ensures production precision, but also enhances job productivity and workplace safety. The rise of artificial intelligence has caused significant changes in the manufacturing industry as a whole. Without exception, the manufacturing industry must rely on AI technology to accomplish automation and intelligent development, as well as to improve productivity. Using artificial intelligence to categorize mechanical components, we may propose parts from a based solely on an image or CAD model. To find a necessary component in a machines we must currently browse through a catalogue and be able to discern which part you want based on the available possibilities and your understanding of the catalogue. There are serial numbers to memorize since a single digit or character change might indicate a different sort of part. The algorithm will choose which sections are the best and will significantly facilitate our search.
Breeding and Migratory Bird Diversity in Iğdır Province (Eastern Anatolia)
Authors: ÖZKOÇ Ömral Ünsal
Published: December 2022

The aim of this study was to contribute to the knowledge of avian diversity and breeding species in Türkiye. Observations were carried out in Iğdır Province within a total of 40 days spread throughout the migration and breeding periods of 2017-2018. Regional status and breeding codes were determined for each species. Some winter visitors have also been observed during the early stages of the spring migration. In the study, 192 species were identified belonging to 50 families from 20 orders and 58 residents, 83 summer visitors, 11 winter visitors, and 40 transit migratory birds. According to the result of the recording breeding behavior, 52 bird species were classified as confirmed breeders, 36 as probable breeders, and 70 as possible breeders. According to IUCN Red List, 10 globally threatened species (Haematopus ostralegus, Vanellus vanellus, Numenius arquata, Gallinago media, Gypaetus barbatus, Aegypius monachus, Circus macrourus, Aythya ferina, Streptopelia turtur, Neophron percnopterus) were observed. Aras Valley and Aralık-Karasu Wetlands are the most important areas for birds. The conservation of these areas is of high importance in the region for migratory birds.
Peningkatan Hasil Belajar Matematika Materi Pecahan Melalui Model Make A Match Pada Peserta Didik
Authors: Dika Nurhayati  , Setyawati Dwi , Maharbid Dian Anggraeni
Published: December 2022

Rendahnya prestasi matematika siswa kelas III di SD Negeri Ngajaran 03 merupakan akibat dari metode mengajar guru yang monoton. Padahal pelajaran matematika sangat penting bagi kehidupan sehari-hari, khususnya bagi siswa, sehingga guru harus berinovasi dengan memasukkan metode pembelajaran “Make a Match” ke dalam pembelajaran mata pelajaran Matematika untuk meningkatkan hasil belajar siswa yang rendah. Jenis penelitian ini dibagi menjadi 2 siklus. Setiap siklus yang diteliti meliputi perencanaan, pelaksanaan, observasi, dan evaluasi. Hasil penelitian menunjukkan bahwa nilai siswa yang mencapai KKM lebih dari 65; khusus pada Pra-Siklus, diketahui nilai dari 29 siswa yang tuntas dalam pembelajaran sebanyak 10 siswa (34,5%) dan yang tidak tuntas sebanyak 19 siswa (65,5%), dengan nilai rata-rata 57,93. Pada Siklus I, 15 siswa (52,5%) yang tuntas dalam pembelajaran dan 19 siswa (65,5%), dengan nilai rata-rata 57,93. Pada Siklus II, 15 siswa (52,5%) yang tidak tuntas dalam pembelajaran dan 19 siswa (65,5%), dengan nilai rata-rata 57,93. Pada Siklus I, 15 siswa (52%) yang tuntas belajar, berbanding dengan 14 siswa (48%) dengan nilai 63,96 yang belum tuntas. Siklus II terjadi peningkatan hingga 26 siswa (90%) yang tuntas belajar, sedangkan yang tidak tuntas hanya 3 siswa (10%) dengan nilai 73,96. Atas dasar hasil pengamatan, evaluasi, dan revisi pada setiap pelaksanaan tindakan kelas, maka dapat disimpulkan bahwa pembelajaran model “Make a Match” dapat meningkatkan kemampuan pemecahan soal pecahan pada siswa SD Negeri Ngajaran 03
Kemampuan Menulis Permulaan Siswa SD Pada Masa Pandemi Covid-19
Authors: Ayuningtyas Dinda Aprilia , Suharjuddin
Published: December 2022

Pada observasi yang sudah dilakukan oleh peneliti, peneliti memilih permasalahan tentang kesulitan menulis permulaan pada siswa kelas IIIC di SDN Harapan Baru II, menulis permulaan dianggap akan menjadi dasar dalam peningkatan dan pengembangan kemampuan siswa pada jenjang selanjutnya, sehingga penelitian ini bertujuan untuk mencari tau kesulitan yang dialami siswa dan mencari tau faktor faktor penyebab siswa mengalami kesulitan menulis permulan. Metode yang dipakai dalam penelitian ini dalah kualitatif dengan pendekatan studi kasus dimana peneliti ingin mengetahui kesulitan menulis yang ada pada siswa kelas III C dan peneliti ingin mengetahui faktor yang menyebabkan kesulitan dalam menulis. Penelitian ini dapat digunakan untuk melihat faktor apa saja yang menyebabkan kesulitan menulis permulaan sehingga guru dapat melihat apa saja kesulitan yang dialami siswa dan memperbaiki hasil tulisan siswa.
PENELUSURAN MORTALITY RISK FACTORS DAN DIGITAL INNOVATION DALAM MEMBANGUN KETAHANAN USAHA MIKRO, KECIL, DAN MENENGAH (UMKM) DI KOTA MAKASSAR
Authors: Hardi Rudi , Khaerah Nur , Putra Muhammad Amril Pratama , Nurjannah Nurjannah , Ismawati Ismawati , Sari Mayang , Fajar Muhammad
Published: December 2022

Permasalahan yang dihadapi UMKM yaitu kualitas SDM, kepemilikan, pembiayaan, pemasaran, kesulitan bersaing dengan perusahaan yang besar.Selain itu, masih berorientasi jangka pendek dan rendahnya konsep inovasi yang sistematis. Untuk dapat tetap hidup, UMKM perlu menumbuhkan iklim inovasi serta penguasaan teknologi, khususnya yang terkait dengan transformasi digital. Tujuan penelitian ini adalah menelusuri Faktor Risiko Kematian dan Inovasi Digital pada UMKM untuk menemukan strategi membangun ketahanan UMKM dari keterpurukan lebih jauh. Terutama  menelusuri dan mengidentifikasi Mortality Risk Factors sebagai indikator kekuatan bertahan UMKM dari kematian. Serta, menelusuri inovasi digital sebagai syarat penting UMKM untuk dapat beradaftasi pada perkembangan digitalisasi usaha. Metode Penelitian  ini  menggunakan  kombinasi  metodologi  penelitian  yaitu  metode kuantitatif, metode kualitatif, serta historical analysis. Metode kualitatif menggunakan pendekatan observer-participant.   Metode kuantitatif yaitu melalui cross-sectional dilakukan dengan convenience sampling, atau availability sampling. Historical analysis digunakan untuk dokumentasi situasi UMKM masa lalu. Hasil Penelitian menunjukkan bahawa permasalahan yang dihadapi UMKM di kota Makassar yang menjadi faktor  yang dapat mendorong risiko kematian (risiko kebangkrutan/”gulung tikar”) yaitu kualitas SDM, kepemilikan, pembiayaan, pemasaran, kesulitan bersaing dengan perusahaan yang besar serta masih berorientasi jangka pendek dan rendahnya penggunaan inovasi yang sistematis. Kemudian faktor yang paling dominan penyebab risiko kematian UMKM adalah: manajemen, wirausaha, dan inovasi. Dalam 'wirausaha' perlu meningkatkan keterampilan dan kompetensi yang akan mencerminkan produktivitas organisasi. Dalam manajemen, wirausahawan harus mengetahui semua alat yang diperlukan dan tersedia untuk kinerja bisnis yang baik dan meminimalkan kegagalan sambil meningkatkan manajemen. Melalui inovasi, produk dan layanan diciptakan untuk melayani konsumen, dan proses organisasi dirampingkan untuk meningkatkan produktivitas bisnis.
On the composition of the type series of the Kashgar Racerunner, Eremias buechneri Bedriaga, 1907 (Sauria, Lacertidae)
Authors: Milto K.D. , Ananjeva N.B.
Published: December 2022

The Kashgar Racerunner Eremias buechneri Bedriaga, 1907 is a member of the taxonomically most complicated group, i.e. E. multiocellata – E. przewalskii complex, together with about a dozen of other species inhabiting predominantly arid landscapes of Central Asia. Eremias buechneri is one of the poorly studied representatives of this diverse group of species. This species was described in 1907 by Jakob von Bedriaga based on the study of specimens collected in Central Asia by N.M. Przewalsky and M.W. Pewzow. This species is practically not present in the collections of museums around the world and is known from a limited number of specimens. We clarify the composition of the type series used in in the original description of this species in accordance with article 72.4.1 of the International Code of Zoological Nomenclature and we propose to consider as a type series the specimens mentioned by the author in his description of 1907, with catalogue numbers in the collection of the Zoological Museum (since 1931, the Zoological Institute) clarified from the results of the N.M. Przewalsky expedition reported by Bedriaga (1912) and thus to expand the type series to 59 specimens (1 lectotype and 58 paralectotypes). Of these, four paralectotypes are lost (ZISP 7264.9, 7279.6, 7089.4 and 7264.4) and four specimens are in very poor condition, almost destroyed (ZISP 8286.1–4). Thus, the actual number of specimens currently stored at the Zoological Institute is 55. The paratype E. buechneri ZISP 9131 has been genotyped. Molecular genetic identification of specimens in the type series from different parts of the range appears promising as a future avenue of research.
Activity of catalase in overwintering females of mosquitoes Culex pipiens, Culex torrentium, and Anopheles maculipennis s.l. (Diptera: Culicidae)
Authors: Razygraev A.V.
Published: December 2022

Catalase, an antioxidant enzyme, is present in tissues of most organisms. In mosquitoes, such as Culex pipiens L., catalase maintains prolonged lifespan and fertility of hibernating females. The sibling species for Cx. pipiens, Cx. torrentium Martini, is more abundant and even prevalent over Cx. pipiens in regions with short growing season and cool climate. Females of Cx. torrentium are difficult to discriminate from Cx. pipiens by morphological traits and can be identified probabilistically using r(2+3)/r3 wing vein index. The present study shows that in Cx. pipiens/torrentium, there is a significant positive correlation between r(2+3)/r3 wing vein index and catalase activity (rho=0.606, p=0.0027), indicating that enzyme activity in Cx. torrentium, in general, higher than in its sibling species, Cx. pipiens. When overwintering females of Cx. pipiens and Anopheles maculipennis s.l. were compared, definitely higher catalase activity in A. maculipennis s.l. was found, and this is in good agreement with the observations that A. maculipennis s.l. females choose cooler hibernacula. Higher catalase activity in overwintering females of Cx. torrentium and A. maculipennis s.l. (in comparison with that of Cx. pipiens) may be considered a better adaptation of Cx. torrentium and A. maculipennis s.l. for stressful conditions during overwintering.
OS FISIOTERAPEUTAS ESTÃO MAIS SUJEITOS À DANOS FÍSICOS OU PSICOSSOCIAIS?
Authors: Calandrelli Martins Líbyna Thaynara , Borges Dias Alex Carrér , Martins Prudente Cejane Oliveira , Porto Celmo Celeno
Published: December 2022

Introdução: Os fisioterapeutas estão sujeitos aos riscos ergonômicos, ambientais, psicossociais que podem contribuir para o surgimento dos distúrbios ocupacionais relacionados ao trabalho (DORT). Objetivo: O objetivo do presente estudo foi avaliar os danos relacionados ao trabalho de fisioterapeutas. Trata-se de um estudo transversal realizado com 77 profissionais fisioterapeutas atuantes no município de Goiânia. Foi utilizado a Escala de Avaliação dos Danos Relacionado ao Trabalho (EADRT) que avaliou os fatores danos sociais, psicológicos e físicos. Resultados: A média de idade dos participantes foi de 30,34 (±5,76) anos, apresentando maior prevalência do sexo feminino (77,9%). Encontrou-se uma pior pontuação na área de saúde da mulher em relação aos danos físicos, assim como uma avaliação crítica relacionada aos danos psicológicos. As especialidades saúde da mulher e dermatofuncional foram as únicas apresentarem uma avaliação crítica em relação aos danos sociais. Houve uma avaliação crítica referente aos danos físicos dos fisioterapeutas, o que correspondeu a 69,2% dos participantes, por outro lado, encontrou-se uma avaliação mais positiva em relação aos danos psicológicos e sócias, correspondendo respectivamente 69,2% e 84,6%. Conclusão: O profissional fisioterapeuta está sujeito a danos físicos, psicológicos e sociais nos diferentes campos de atuação, entretanto, os fisioterapeutas neste estudo estiveram mais sujeitos aos danos físicos ao se comparar com danos psicológicos e sociais. E o campo de atuação da saúde da mulher apresentou piores pontuações nos três fatores analisados.
ADHERENCE TO CARDIOVASCULAR REHABILITATION WITH THE USE OF EXERGAMING: A SYSTEMATIC REVIEW
Authors: Novais Michelli Christina Magalhães , Carvalho Vitor Oliveira , Sampaio Laís Fernanda Duarte , Lima Yone Kauane da Silva , Lima Thaysa Vitorio , Conceição Lino Sergio Rocha , Correia Helena França
Published: December 2022

Introdução: Estudos mostram que há uma baixa adesão à reabilitação cardiovascular (RCV) implicando em limitações quanto aos benefícios esperados. É importante investigar se a diversificação de intervenções já aplicadas na RCV, como a adoção do exergaming, pode proporcionar maior adesão à esse tratamento. Objetivo: Revisar estudos que investigaram a adesão intragrupo à RCV de pacientes em uso do exergaming e comparar, intergrupos, com pacientes submetidos a RCV convencional. Métodos: Trata-se de uma revisão sistemática que incluiu estudos de intervenção originais, indexados em bases de dados e publicados até abril de 2021, sem restrições de idioma. A busca foi realizada no PubMed/Medline, Web of Science, Scopus, Cochrane e PEDro, em abril de 2021. Resultados: Foram incluídos 8 estudos. Em 3 deles, a média de adesão às sessões de RCV com exergaming foi de 77%. Em outro estudo, cerca de 60% dos participantes estavam mais de 80% aderentes ao tempo de jogo recomendado. No quinto estudo, o tempo médio de uso do exergaming foi de 28 ± 13 minutos/dia, superior ao recomendado de 20 minutos/dia. No sexto estudo, a mediana de atendimento individual foi de 96%. No sétimo, houve 100% de adesão às sessões de RCV. Já no oitavo estudo, houve aumento significativo na adesão em 12 semanas de RCV com exergaming (72,87% para 82,80%) e redução quando exergaming foi descontinuado (82,80% para 65,48%, p < 0,05). Conclusão: A melhor evidência disponível demonstra um efeito positivo do exergaming na adesão do paciente à RCV.
SINTOMAS DE ANSIEDADE E DEPRESSÃO EM ACADÊMICOS DE FISIOTERAPIA DURANTE A PANDEMIA DA COVID-19
Authors: De Morais Elizabeth Rodrigues , De Castro Aline Fernandes , Chaves Bárbara Glenda Castro
Published: December 2022

Introdução: O meio acadêmico é marcado por inúmeros fatores geradores de transtornos emocionais, essa realidade pode ser agravada pela pandemia da Covid-19. Objetivo: Verificar a prevalência de sintomas de depressão e ansiedade entre os acadêmicos de fisioterapia de uma Instituição Pública de Goiás durante a pandemia da COVID-19, bem como os fatores associados a esses sintomas. Métodos: Estudo transversal analítico, realizado com alunos do curso de Fisioterapia de uma universidade pública de Goiás. Um questionário sociodemográfico foi utilizado para avaliar os hábitos de vida e saúde e perfil sociodemográfico, para avaliar os sintomas de depressão e ansiedade foi utilizado o Inventario de Beck de Depressão (BDI) e o Inventario de Ansiedade Beck (BAI). Resultados: Foram analisados 120 questionários. A mediana de idade foi de 23 anos (21,0-23,5) com predomínio do sexo feminino (85%). A prevalência de sintomas moderados a grave para ansiedade e depressão foi de 57,5% e 38,3% respectivamente. Apresentaram associação com os sintomas emocionais: relato de doença, uso de medicamentos, auto relato de ansiedade e depressão, renda salarial baixa, apoio familiar, tempo de lazer reduzido e prática de exercícios físicos (p<0,05). Conclusão: Foi encontrado alta prevalência de depressão e ansiedade nos acadêmicos de fisioterapia, os fatores associados com ansiedade e depressão foram sexo feminino, ter doença, uso de ansiolíticos e antidepressivos e tempo de lazer insuficiente. Houve associação com a ansiedade o uso de medicamentos e baixa renda e com a depressão não praticar atividade física e apoio familiar.
VÍNCULO MÃE-FILHO E OPORTUNIDADES PARA O DESENVOLVIMENTO MOTOR DE LACTENTES EXPOSTOS E NÃO EXPOSTOS AO HIV
Authors: Ruivo Camila Ortega , Pádua Raissa Felipe , Sá Cristina Dos Santos Cardoso de
Published: December 2022

Objetivos: Caracterizar e avaliar o vínculo mãe-filho, as oportunidades domiciliares e o desenvolvimento motor de lactentes expostos e não expostos ao HIV entre 4 a 12 meses de idade. Métodos: Estudo transversal com 48 lactentes e suas mães, sendo 21 expostos ao HIV e 27 não expostos.  As mães responderam ao Protocolo de Avaliação do Vínculo Mãe-Filho, o questionário Affordances no Ambiente Domiciliar, o desenvolvimento motor foi avaliado pela Alberta Infant Motor Scale (AIMS). Aplicou-se a correlação de Pearson, e nível de significância p-valor <0,05. Resultados: A correlação entre vínculo mãe-filho e grupo é positiva (r=0,330; p=0,022). Os lactentes expostos ao HIV apresentaram menor vínculo mãe-filho (p=0,006). Conclusão: Houve relação entre menor vínculo mãe-filho entre os lactentes expostos ao HIV, mas não houve diferenças em relação ao desenvolvimento motor e as oportunidades domiciliares.
Analysis of genetic diversity of valuable walnut species collected at N.V. Tsitsin Main Botanical Garden of the Russian Academy of Sciences Using SSR markers
Authors: Suprun I. I. , Stepanov I. V. , Sokolova V. V. , Al-Nakib E. A.
Published: December 2022

Walnut is one of the most economically significant nut crops. Evaluation of the genetic structure of the domestic walnut gene plasma using modern molecular genetic approaches is a relevant research task. The walnut samples collected by Tsitsin Main Moscow Botanical Garden of Academy of Sciences (MBG RAS) are of particular importance for breeding practice aimed at increasing winter freezing tolerance of plants. The seed material for this collection was introduced from different regions of the former Soviet Union, including Tajikistan, Kyrgyzstan, Ukraine, Belarus, as well as regions of Russia. The MBG RAS collection presents interest as a breeding material for mobilizing the genetic resources and replenishing the gene pool of the South of Russia with new, economically valuable walnut varieties. This work aims to analyze the genetic diversity of a J. regia genotype sample, which includes the most valuable forms from the MBG RAS collection, in order to establish their genetic relationships with samples representing the walnut gene pool of the South of Russia. The genetic analysis of the studied walnut species and varieties was carried out using eight SSR markers: WGA001, WGA376, WGA069, WGA276, WGA009, WGA202, WGA089, and WGA054. The polymorphism of microsatellite DNA markers established during genotyping indicated a high heterogeneity between the MBG RAS walnut sample and genetic resources in other regions. An analysis of genetic relationships using UPGMA and PCoA clustering methods revealed the genetic isolation of most samples in the MBG RAS collection from walnut varieties in the South of Russia. The most genetically distant samples in the MBG RAS collection were found to be 199, 196, 236, 256, 106, and 134. Therefore, these samples should be introduced in the gene pool of North-Caucasus Federal Scientific Center of Horticulture, Viticulture, and Wine-making and Nikitsky Botanical Garden with the purpose of increasing the heterogeneity of their gene pools.
Impact of the B-Plus white pearl (Belyi Zhemchug) preparation on the spring frost tolerance, yield and quality of apple crops
Authors: Ozherel’eva Z. E. , Prudnikov P. S.
Published: December 2022

In 2021–2022, experiments were conducted at the Laboratory of Fruit Crop Resistance Physiology, All-Russia Institute for Fruit Crops Breeding (VNIISPK), to investigate the action of the “White Pearl Antifreeze” (Belyi Zhemchug Antifriz) phytomodulator and the “White Pearl Drip Ca + Mg” (Belyi Zhemchug Drip Ca+Mg) phytocorrector produced by the AgroPlus Group of Companies, LLC. Experimental and control plots were characterized by dark-gray forest soils with a humus content of 3-4 % and a humus horizon thickness of 30–35 cm. Apple trees cv. Sinap Orlovsky (VNIISPK) grafted on semi-dwarf rootstock 54-118 were planted in 2013 according to a 6 x 3 m scheme. Natural grassing was used in row spacings; herbicides were applied around the seedlings. The experimental design included: 1) control (water treatment) and 2) foliar treatment with a 1 % solution of “White Pearl Antifreeze” + a 1 % solution of “White Pearl Drip Ca+Mg”. The experiment was conducted in three replications with five observed trees in each. Our aim was to assess the effect of the mentioned preparations on the spring frost tolerance, yield, and quality of apple fruit under the weather conditions of 2021. Foliar treatments with the studied preparations reduced the frost damage to Sinap Orlovsky apple buds by 6.3 % at -3.5 °С and by 10.4 % at -4 °С. The conducted summer foliar treatments with the organomineral mixture under study intensified the growth and ripening of apple fruit. The improved protein-carbohydrate metabolism, water regime, photosynthetic activity, and donor-acceptor leaf–fruit relations increased the fruit weight by 10 g and the yield by 1.8 times. The conclusion is made that the B-PLUS “White Pearl Antifreeze” preparation exhibits a complex effect in terms of increasing plant tolerance to low-temperature spring damage, thus improving the yield and quality of apple crops.
Variations in phenolic content in tea under various processing methods
Authors: Platonova N. B. , Kunina V. A. , Belous O. G.
Published: December 2022

Variations in the phenolic content (total polyphenols, theaflavins, and thearubigins) of unconventional brands of ready-made tea (white, red, GABA) depending on different processing methods are discussed. Research in this direction has been carried out at the Subtropical Scientific Center of the Russian Academy of Sciences (FRC SSC RAS, Sochi) since 2017. Krasnodar tea was shown to contain polyphenols, theaflavins, and thearubigins in the amount of 18.47, 0.14, and 0.79 mg/g, respectively. Non-fermented and semi-fermented teas contain the highest amounts of polyphenols: white (16.63 mg/g), green (16.51 mg/g), and light GABA (16.47 mg/g). When processing light GABA tea, no change in the content of polyphenols occurs; however, the number of flavonoid pigments reduces significantly. Thus, the content of theaflavins (0.02 mg/g) remains at the level of white tea (0.03 mg/g), while that of thearubigins decreases significantly (0.26 mg/g as compared to 0.43–0.46 mg/g in white and green tea, respectively). The content of polyphenols in fermented teas (black, red) is significantly lower than that in raw material and non-fermented teas (НСР05 = 1.18). At the same time, black tea contains theaflavins (0.04 mg/g) and thearubigins (0.95 mg/g) in higher levels. To a certain extent, red tea is inferior to black tea in terms of polyphenols, although red tea is comparable to white and green teas in terms of flavonoids (0.04 mg/g of theaflavins and 0.39 mg/g of thearubigins). With respect to phenolic components, dark GABA tea approaches nonfermented and semi-fermented teas, which increases its nutritional value. The obtained data can be used when developing approaches to regulating the quality characteristics of ready-made tea produced under humid subtropical conditions in Russia, ensuring the preservation and improvement of product quality.
Effects of various nitrogen fertilizers and the Extrasol biopreparation on the quality of garden strawberry (Fragaria×ananassa Duch.) at fertigation with drip irrigation on soddy podzolic soils
Authors: Pomyaksheva L. V. , Konovalov S. N. , Chebotar V. K.
Published: December 2022

Current approaches to land use and agricultural production are increasingly aimed at achieving high productivity through the use of crop rotation, siderites, integrated plant protection, minimized soil cultivation, microbiological fertilizers, and biological preparations. Modern microbiological preparations enhance the uptake of nitrogen and ash elements by plants, improving the rhizosphere of plants and the quality of strawberry fruit. Aim. To establish the effect of Extrasol applied using drip irrigation and various forms of mineral nitrogen fertilizers on the chemical composition of leaves and fruit of garden strawberry.Materials and methods. Garden strawberry plants of the Rusich and Troitskaya cultivars were treated with Extrasol and mineral fertilizers. Experiments were carried out in 2017–2020 at open-ground plots of the Federal Horticultural Center for Breeding, Agrotechnology and Nursery (Moscow Oblast). The experimental plots were characterized by soddy podzolic soils of medium-loam granulometric composition. Plant samples were analyzed using conventional methods. The experimental scheme consisted in the application of various nitrogen fertilizers (ammonium nitrate, urea, and ammonium sulfate) either in combination (2 mL/L of the working solution) or without Extrasol. Conclusions. In strawberry cv. Rusich, the use of ammonium nitrate increased the calcium content in plant leaves and decreased its content in fruit, which negatively affected the crop quality. Mineral fertilizers applied in combination with Extrasol increased the nitrogen content in leaves and fruit. The combined use of the amide form of nitrogen (urea) and Extrasol adversely affected the level of nitrates in cv. Troitskaya fruit. The use of fertigation and Extrasol reduced the amount of soluble dry substances in strawberry fruit.
A biological method for managing the yield of Libya grape variety on a 41B Rootstock
Authors: Petrov V. S. , Fisyura A. V. , Marmorshtein A. A.
Published: December 2022

Advances in grapevine biotechnology are associated with manipulation of vegetative and generative plant organs, effective use of the soil and climate potential of agricultural lands, and biological features of grape genotypes. Grapevine biotechnology allows grape productivity to be increased without additional investments. In this work, we studied table grapes of the Libya variety grafted onto a Chasselas.×V. Berlandieri 41B rootstock to determine variations in grape productivity depending on the different load of vines with shoots and bunches. The research was carried out in the Central Agroecological Zone of Viticulture (fourth subzone) of the Krasnodar Krai, in vineyards with drip irrigation and covered viticulture. The vines were planted according to a 3.8×2.0 m scheme with a density of 1316 plants per hectare. The vines were supported with a high-trunk two-arm horizontal cordon system. The average annual air temperature at the experimental site equaled +12.5... 13.0 °С; the sum of active temperatures was 3 900-4 100 °С; the maximum temperature during vegetation reached +40 °С; the minimum temperature of -30 °С was recorded in winters during dormancy. The annual precipitation level comprised 700-800 mm. The soils were low-humus, leached powerful chernozems. In terms of productivity, grapes of the Livia variety respond effectively to canopy management techniques. In this work, changes in bunch weight and grape yield were monitored depending on the load of vines with shoots and bunches. Under the studied agroecological conditions, the largest bunch mass of 870 g was achieved at the lowest load of 20 shoots and 22 bunches per vine. The maximum grape yield of 36.3 t/ha was observed with an average load of 26 shoots per vine and the largest load of 37 bunches per vine. The dependence of yield on shoot number was rather low, r = 0.08; on bunch number was medium, r = 0.53; on bunch mass was high, r = 0.75. The largest share of marketable grape yield of 98% was achieved at the load of 20 shoots and 22 bunches per vine.
Biotechnological and molecular genetic methods in grape breeding
Authors: Likhovskoi V. V. , Zlenko V. A. , Khvatkov P. A. , Maletich G. K. , Spotar G. Yu. , Lushchay Е. А. , Klimenko V. P.
Published: December 2022

The development of new grape varieties with improved quality and resistance against environmental factors using biotechnological methods is a pressing task in the context of import substitution policy implementation. Due to the high heterogeneity of grape varieties, techniques for regenerating plants from embryogenic callus by somatic embryogenesis have been developed only for a small number of genotypes. This work presents a versatile approach to the development of globular, heart, and torpedo embryos in various grape genotypes. Experiments were carried out using cultures of colchicine embryogenic cell suspensions and somatic globular embryos of the E-342 hybrid form in liquid media. The developed methodology allows the protocols of embryogenesis and polyploidy induction to be effectively improved. The versatility of the presented methodology for polyploidy induction and somatic embryogenesis in grape plants is ensured by a fourfold reduction in the concentration of inorganic nitrogen and vitamins in the NN and PG media and the addition of organic nitrogen and other biological active substances at the stages of embryogenic callus development, colchicination, and development of somatic embryoids in liquid media. The methods of indirect ploidy determination by the properties of the grape leaf epidermis were studied and implemented. Nine promising somaclones were preliminary selected based on a set of four features. It was established that full-fledged transgenic grape plants can only be obtained by the method of transformation, which involves the production of embryogenic callus from a leaf explant, its subsequent passage into a liquid culture to obtain a liquid embryo culture, and the transformation of this culture. In total, 300 leaf explants of the Libya variety and 1 100 globular embryos of the Podarok Magaracha variety were transformed. As a result, six callus kanamycin-resistant lines of the Libya variety and six lines of transgenic plants of the Podarok Magaracha variety were selected. Following genotyping based on nine nuclear microsatellite loci, seven unknown forms with a seedless phenotype were identified. Among the population of hybrid seedlings, hybrids having alleles associated with seedlessness were revealed using the VMC7f2 and p3_VvAGL11 MAS markers.
The Visual characteristics of railside landscape for tourists’ satisfaction
Authors:   University of Moratuwa, Sri Lanka, Guruge S.P.P.G.D.K. , De Silva W. ,   University of Moratuwa, Sri Lanka
Published: December 2022

Moving Landscape Aesthetic Quality (MLAQ) has been a topic that had taken less attention from the researchers. Though a great effort is given to interpret the aesthetic quality of the landscape, the tourists’ preference for the moving journey has not been much talked about. The objective of this research is to study the Independent and interdependent moving Railside landscape character through landscape indicators, which is found by considering the tourist satisfaction. This paper gives important information on human landscape preference (perception) which will add value to the moving railway landscape. The study is based on seven landscape indicators (coherence, disturbance, complexity, mystery, naturalness, Imageability, and visual scale). Colombo Fort to Badulla railway landscape experience is investigated with a sample of thirty participants. Data was collected based on an online questionnaire survey with quantitative and qualitative data. Six case studies were selected for the survey by analyzing the overall result of the areas by considering the geomorphology and the spatial character of the landscape. Findings revealed that the moving landscape character of the railway journey inspires the tourist satisfaction.
User experience in traditional domestic preparation products in different cultures of Sri Lanka: Special reference to String Hopper Press (“Idiappa Wangediya”)
Authors:   University of Moratuwa, Sri Lanka, Hettiarachchi A.D. , Ranasinghe W.M.N.D.
Published: December 2022

Traditional domestic manual handling products have many unique characteristics according to cultural backgrounds. Although to complete one task, people are using different products in different contexts in Sri Lanka. These products have cultural (Sinhala, Tamil, Muslim) related practices, thinking patterns and different user experiences with a specific context. But after globalization these products have been developed and replaced with other products. Therefore, user perspectives, behaviors, and relationships with cultural products and users have changed. Therefore, research contains user experience in String Hopper Press (“Idiappa Wangediya”) and its variations in many other cultures in Sri Lanka. Samples are selected according to the current use and available products in the market. The analysis is based on User Experience theories. Finally, traditional products used in different cultures have different user experiences that are gained from cultural values. Therefore, it is hard for users to adapt to other products from different cultures and hard to change usual behaviors with the product