bluuebunny/crossref_metadata_2025 huggingface dataset:
Risk factors for falls in the elderly
Authors: Costa Alice Gabrielle de Sousa , Araujo Thelma Leite de , Oliveira Ana Railka de Souza , Morais Huana Carolina Cândido , Silva Viviane Martins da , Lopes Marcos Venícios de Oliveira
Published: February 2023

The occurrence of falls represents an obstacle in the health of the elderly, and it contributes to increase their dependence. This study aimed to investigate the intrinsic and extrinsic risk factors, and possible statistical associations for falls in elderly people in the last six months. A case-control study with quantitative approach developed in three Rehabilitation Associations and one Social Assistance Center, with two groups with thirty participants each, a group with falls (case) and another group without falls (control). The data were collected from January to April 2010 by a form, and were organized is spreadsheets and analyzed by a statistical program. The case group presented worst intrinsic conditions and more extrinsic factors. Feet alterations, impaired balance and proprioceptive deficit were highlighted among the intrinsic risk factors that were statistically significant. The conclusion is the reinforcement of multifactorial hypothesis for falls occurrence with possibilities for nurse’s performance
Profile of tuberculosis patients
Authors: Cavalcante Elisângela Franco de Oliveira , Silva Denise Maria Guerreiro Vieira da
Published: February 2023

The objective was to build the profile of people affected by TB and describe how the disease presents itself in the city of Natal, Rio Grande do Norte, Brazil. It outlined a descriptive epidemiological study, with reported cases of tuberculosis in the National Notifiable Diseases System between 2006 and 2010. 2,632 cases were reported, by year of diagnosis. Disease incidence was greater when compared with national and other studies. The disease has shown cure rates slightly below the national figures. Diseases associated to the tuberculosis were present. Certain population groups are more likely to develop the disease in the city, most cases occurring among men in their economically active age group, and less profitable occupations. The existence of health professionals with tuberculosis was shown. The disease is highlighted in the social and economic context of the region and presents itself as a health problem to be faced by health professionals, health managers and population.
Social representations of postpartum women on prenatal care in primary health care
Authors: Guerreiro Eryjosy Marculino , Rodrigues Dafne Paiva , Queiroz Ana Beatriz Azevedo , Ferreira Márcia de Assunção , Rodrigues Ivana Rios , Melo Laura Pinto Torres de
Published: February 2023

This article aimed at capturing the social representations of postpartum women on prenatal care in primary health care. This is a descriptive, qualitative study, guided by the Theory of Social Representations, developed in nine Family Health Centers, in Fortaleza, Ceará, Brazil, from May to July, 2012. 31 women on postpartum were interviewed through semi-structured interviews. The interviews were recorded, fully transcribed and processed through ALCESTE software - 2010 version. The results observed in the lexical analysis of the interviews revealed the distribution of contents in four classes. Classes 4 and 1 dealing with prenatal care were explored in this study. Social representations of users about the prenatal are anchored in the protocol dimension and socio-educational dimension. The implantation and the maintenance of activities are necessary in order to share knowledge and interaction among the users
Perceptions of the elderly about cardiovascular risk factors
Authors: Richter Cleusa Maria , Bettinelli Luiz Antonio , Pasqualotti Adriano , Viecili Paulo Ricardo Nazário , Erdmann Alacoque Lorenzini , Callegaro Higashi Giovana Dorneles
Published: February 2023

A qualitative exploratory study that aimed to understand the perceptions of a group of elderly people on cardiovascularrisk factors. The study included 100 elderly of both sexes, of the city of Cruz Alta-RS, Brazil, 2009. Data collectionhappened through semi-structured interviews. From the thematic analysis were constructed the following threecategories: Lack of knowledge on the diseases (diabetes mellitus and hypertension) as cardiovascular risk factors; Safetyin drug therapy to minimize the risk factors; and Eating habits and healthy lifestyles. Based on the results, we suggestprioritizing the development of an educational process in multidisciplinary health directed to the specifics of the elderly,in order to reduce the cardiovascular risk factors and qualify their living.
Child and youth cancer: profile of deaths
Authors: Marchi Joisy Aparecida , Wakiuchi Julia , Sales Catarina Aparecida , Mathias Thais Aidar de Freitas , Fernandes Carlos Alexandre Molena
Published: February 2023

This study is aimed at characterizing the deaths caused by malignant neoplasias in children and adolescents living in the state of Paraná, Brazil between 2001 and 2010. It is a quantitative, descriptive, transversal study, based on secondary data, obtained through the data processing department of the Sistema Único de Saúde from July to December, 2012. The following variables were analyzed: gender, age, race and city of residence. As a measure of association, odds ratio was used, confirmed by the χ2. The leukemia, central nervous system neoplasias and lymphomas, female gender and white race were highlight topics. Teens had about three times greater chance of dying of cancer compared to children. The child and youth neoplasia deserves special attention on the condition of vulnerability of this group, and further studies are needed to assess the association with possible risk factors.
Jubileusz 40-lecia Katedry Historii Wychowania Uniwersytetu w Białymstoku i jej humanistyczny szacunek dla człowieka
Authors:   Uniwersytet w Białymstoku, Kalisz Łukasz
Published: February 2023

The article presents the history and organizational structure of the Department of the History of Education operating at the University of Bialystok since 1980. The author presented the main areas of research undertaken by the employees of the Department, as well as their scientific and organizational achievements. Due to the celebrations of the 40th anniversary of the Department of History of Education headed by Professor dr hab. Elwira J. Kryńska, the article presents the main assumptions of the International Scientific Conference “Child in History – Between Dignity and Enslavement”, which took place on May 24-25, 2021.
Związek między kulturą Masajów a edukacją dziewcząt: przypadek hrabstwa Narok North w Kenii
Authors:   Uniwersytet Loránda Eötvösa (Węgry), Maringa John Njeru M.
Published: February 2023

This research seeks to establish how the Maasai culture impacts the education of girls and women in Narok North Sub-County, Kenya. Education is the instrument of liberation, domination, personal and communal development. Educating a girl ensures that the benefits of education are felt at the family level and even transmitted to future generations. Even though the Government of Kenya accomplished the free primary education policy in 2003 and went further and declared 100% transition of students from primary education to secondary education level in 2020, learning still remains a mirage for some families of the Narok North Sub-County. The dominant Maasai culture has hindered the actualization of the education of girls. This study was conducted using the ethnographic approach. Various groups of people were also interviewed using semi-structured interviews. The data obtained was analyzed using thematic narrative analysis. The study inferred that the community wasn’t enthusiastic about taking their girls and women to school. On school enrollments within Narok County, few girls, compared to boys, enrolled in grade 1 while the transition of leaners from primary schools to secondary schools stood slightly above 60%. This paper recommends radical combined efforts of all stakeholders as a technique of persuading the community to scale up its efforts on education attainment. Among these recommendations is incorporating the Maasai elders in this noble task and also supporting adult education literacy programs for young mothers and women.
Wspierać, czy wychowywać? – Rozłam (anty)pedagogiczny XX wieku a kształcenie przyszłych pedagogów
Authors:   Uniwersytet w Białymstoku, Konopelko Justyna
Published: February 2023

Paradigm diversity in pedagogy shows both the changes over the years in the approach to educational processes and the multiplicity of perspectives in the perception of upbringing. Acquainting future pedagogues with approaches different from the academically accepted provides an opportunity not only to find one’s path of pedagogical thought, but is also a platform for developing critical thinking and improving selection skills, so necessary in this profession. Even views of a radical nature, such as the anti-pedagogical orientation developing in the twentieth century, are an alternative reference point to everyday pedagogical reality and have significant potential for reflection on one’s position on crucial issues.
OONO–/MMP2/MMP9 pathway-mediated apoptosis of porcine granulosa cells is associated with DNA damage
Authors: Lei Kun , Wei Quanwei , Cheng Ying , Wang Zhe , Wu Haoze , Zhao Fang , Ding Wei , Shi Fangxiong
Published: February 2023

In brief

The apoptosis of granulosa cells (GCs) is the main reason for porcine follicular atresia. This study provides a novel mechanism for peroxynitrite anion-mediated GC apoptosis and follicular atresia in porcine ovary.

Granulosa cells play a crucial role in the development of follicles, and their cell apoptosis in the porcine ovary is a major contributor to follicular atresia. Here, we provide a new mechanism for follicular atresia by describing a crucial mechanism by which peroxynitrite anion (OONO–) may cause GC death. We discovered that nitric oxide, oxidative stress level, and OONO– were positively correlated with porcine follicular atresia, which was accompanied by high expression of matrix metalloproteinase 2 (MMP2) and MMP9. We created a model of OONO–-induced apoptosis in GCs and discovered that OONO– could boost the expression of MMP2 and MMP9 and increase the expression of pro-apoptotic proteins and DNA damage. Furthermore, by inhibiting the activities of MMP2 and MMP9, we found that SB-3CT (a specific inhibitor for MMP2 and MMP9) alleviated the decrease in cell survival rates and DNA damage caused by OONO–, which may have been impacted by reducing the cleavage of PARP1 by MMP2 and MMP9. Therefore, our findings imply that OONO– can cause DNA damage to GCs, participating in mediating the expression of pro-apoptotic proteins and inhibiting DNA repair by preventing the activity of PARP1 through MMP2 and MMP9. These results help explain how OONO–/MMP2/MMP9 affects porcine follicular atresia and GC apoptosis.
Intensifiers and epistemic adverbials – On the history of German echt ‘really, lit. real/genuine’
Authors: Ørsnes Bjarne
Published: February 2023

Adverbials of truth or reality such as really (en.), wirklich (de.), verdaderamente (sp.) are cross-linguistically assumed to be a rich source for intensifiers (degree words) as in: (i) Peter is really nice. The epistemic adverbial is reanalysed as a modifier of a predicative adjective in a syntactically ambiguous sentence as in (i). At the same time the emphasis on the truth of the proposition invites the inference that the property in question is amply present. This view on the emergence of intensifiers from adverbials of truth is challenged by the German intensifier echt ‘really, lit. genuine/real’ as in: (ii) Peter ist echt nett ‘Peter is really nice’. In contemporary German echt is very popular as an intensifier, a proposition modifier, a speech-act modifier and a response particle. However, a diachronic analysis of the use of echt as an adverbial in New High German reveals that the intensifier reading develops much earlier than the reading as a proposition modifier, i.e. an epistemic adverbial. The article offers a discussion of the development of echt which sheds a somewhat different light on the relation between intensifiers and epistemic adverbials, and it suggests a unified analysis of the uses of echt in contemporary German which supports Traugott’s view of grammaticalisation as also encompassing an extension of structural scope.
Development, psychometric validation, and cross-cultural comparison of the “Instagram Motives Questionnaire” (IMQ) and the “Instagram Uses and Patterns Questionnaire” (IUPQ)
Authors: Romero Saletti Silvana Melissa , Van den Broucke Stephan , Billieux Joël , Karila Laurent , Kuss Daria J. , Rivera Espejo José Manuel , Sheldon Pavica , Lang Cathryne P. , Zimmer-Gembeck Melanie J. , Zollo Palmyra , Courboin Clara , Diez Dominica , Madison T. Phillip , Ramos-Diaz Jano , Eguia Elias César Augusto , Otiniano Fiorella
Published: February 2023

Background and aims

Social network use is widespread, and the study of Instagram seems to have captured more attention in recent years. However, scale development and validation in the field has fallen short of providing sound scales of Instagram motives and usage patterns that consider the uniqueness of Instagram-related behavior. This paper describes the development, psychometric and cross-cultural validation of two new measurement instruments: the “Instagram Motives Questionnaire” (IMQ) and the “Instagram Uses and Patterns Questionnaire” (IUPQ).

Methods and results

A preliminary set of items was developed for each questionnaire based on a previous qualitative interview study on Instagram motives, uses, and consequences. In the first study, the questionnaires were distributed to a sample of 312 participants aged 18–35 years (M = 23.81; SD = 4.49), and an exploratory factor analysis was performed. A parsimonious and interpretable 6-factor solution that displayed adequate factor loadings and adequate Omega coefficients for both instruments were found. In a second study, the two instruments and other measures of known social network usage correlates and mental health consequences were administered online to 1,418 English-speaking participants aged 18–34 years (M = 21.35; SD = 3.89). Both scales showed good psychometric properties and the factor structure identified in study 1 was reproduced through confirmatory factor analysis. Omega reliability coefficients were adequate. Finally, when performing multi-group CFA along with a French (n = 1,826) and a Spanish (n = 3,040) sample, language and gender invariance were supported. Correlations with other relevant measures indicate good convergent validity of both scales.

Conclusions

The present research provides psychometrically sound instruments for further investigations on Instagram use behaviors.
Random Walks on the Two-Dimensional K-Comb Lattice
Authors: Csáki Endre , Földes Antónia
Published: February 2023

We study the path behavior of the symmetric walk on some special comb-type subsets of ℤ2 which are obtained from ℤ2 by generalizing the comb having finitely many horizontal lines instead of one.
Splitting Edge Partitions of Graphs
Authors: Király Balázs , Szabó Sándor
Published: February 2023

In a typical maximum clique search algorithm when optimality testing is inconclusive a forking takes place. The instance is divided into smaller ones. This is the branching step of the procedure. In order to ensure a balanced work load for the processors for parallel algorithms it is essential that the resulting smaller problems are do not overly vary in difficulty. The so-called splitting partitions of the nodes of the given graph were introduced earlier to meliorate this problem. The paper proposes a splitting partition of the edges for the same purpose. In the lack of available theoretical tools we assess the practical feasibility of constructing suboptimal splitting edge partitions by carrying out numerical experiments. While working with splitting partitions we have realized that they can be utilized as preconditioning tools preliminary to a large scale clique search. The paper will discuss this new found role of the splitting edge partitions as well.
Nursing care management concepts: scoping review
Authors: Barros Aurilívia Carolinne Lima , Menegaz Jouhanna do Carmo , Santos José Luís Guedes dos , Polaro Sandra Helena Isse , Trindade Letícia de Lima , Meschial William Campo
Published: February 2023

ABSTRACT Objectives: to clarify the concepts of Nursing Care Management and Nursing Care Administration in the scientific literature, highlighting approximations and distances between the terms. Methods: scoping review as per Joanna Briggs Institute protocol and preferred reporting items for Systematic Reviews and Meta-analysis extension for Scoping Reviews (PRISMA-ScR). The searches were performed in LILACS, CINAHL, MEDLINE, and Scopus databases. Results: the qualitative analysis, through content analysis, counted 49 studies published between 2007 and 2020. Hospital care was the most evident level of care. It was identified that nursing care management aims at the macropolitical performance of nurses and mobilizes skills essentially strategic-cognitive, while Nursing Care Administration aims at the micropolitical performance of nurses, requiring essentially strategic-administrative skills. Final Considerations: the study allowed us to propose the conceptualization of the terms and identify the approximations and distances between them.
Contagem cirúrgica: projeto de implementação e manutenção de um procedimento padronizado baseado em evidências
Authors: Gomes Eduardo Tavares , Albuquerque Érica Larissa Marinho Souto de , Pereira Adélia Cristina Monteiro , Püschel Vilanice Alves de Araujo
Published: February 2023

RESUMO Objetivos: relatar a implementação e manutenção de um Procedimento Operacional Padronizado baseado em evidências, para contagem cirúrgica, realizado em hospital universitário. Métodos: trata-se de relato de um projeto de implementação de evidências para contagem cirúrgica, realizado em um hospital universitário, iniciado em dezembro de 2017, e os ciclos subsequentes para melhor desempenho do documento organizacional implementado e manutenção de melhores resultados até março de 2022. Resultados: o relato está dividido em uma apresentação do projeto de implementação de evidências e mais quatro outros ciclos após a implementação, relacionados à manutenção das melhorias. Foi possível elaborar o documento Procedimento Operacional Padrão para a Contagem Cirúrgica no hospital, treinar a equipe de enfermagem, realizar intervenção educativa para as equipes cirúrgicas. Considerações Finais: houve melhora na adesão ao procedimento padronizado no primeiro momento e piora no período relacionado à pandemia. Novos esforços recomeçaram incluindo curso online autoinstrutivo aliado às estratégias do primeiro momento.
Características morfológicas das artérias gástricas esquerda, hepática comum e esplênica. Um estudo descritivo em espécimes cadavéricos humanos
Authors: SALDARRIAGA BLADIMIR , LARROTTA OSCAR , BALLESTEROS LUIS
Published: February 2023

RESUMO Objetivo: avaliar a morfologia dos ramos das artérias do tronco celíaco (CT), gástrica esquerda (LGA), hepática comum (HC) e esplênica (SA) em espécimes cadavéricos de uma amostra de uma população colombiana. Métodos: estudo transversal descritivo de 26 blocos do segmento superior abdominal de cadáveres humanos submetidos a necropsias forenses no Instituto de Medicina Legal de Bucaramanga, Colômbia. Os leitos vasculares do tronco celíaco foram, posteriormente, perfundidos com resina semissintética. Resultados: os diâmetros de LGA, CHA e SA foram 3,6±0,8mm, 5,2±1,2mm e 5,9±1,0mm, respectivamente. Estatisticamente, LGA e SA foram diferentes (p=<0,001). A SA seguiu uma trajetória linear em 8 (31%) amostras, levemente tortuosa em 4 (15%) e tortuosa em 14 (54%). O índice de tortuosidade foi de 1,25±0,18. Dos ramos do ACS, a artéria hepática própria (APH) tinha 4,8±1,2mm de diâmetro e 18,8±9,1mm de comprimento, enquanto a artéria gastroduodenal (GDdA) tinha 4,1±0,8mm. Em 2 casos (7,7%), uma artéria hepática acessória do GIG foi encontrada para fornecer perfusão ao lobo hepático esquerdo. Finalmente, em 2 casos (7,7%) a SA veio independentemente da aorta abdominal. Conclusão: a incidência observada de emergência dos ramos de TC do mesmo nível relatado na literatura é menor. A caracterização, juntamente com suas variantes, de LGA, CHA e SA deve ser considerada em procedimentos cirúrgicos no segmento abdominal superior, para evitar complicações iatrogênicas.
Impact of Roux-en-Y Gastric Bypass and Vertical Gastrectomy on weight loss: a retrospective and longitudinal study in the State of Paraná, Brazil
Authors: GAMBA FERNANDA PEREIRA , SIQUEIRA BRUNA SCHUMAKER , TSUCHIYA RICARDO SHIGUEO , TANAKA TOMAZ MASSAYUKI , GRASSIOLLI SABRINA
Published: February 2023

ABSTRACT Aim: to compare the impact of Roux’s Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG) techniques on body weight reduction over 1 and 5 years after bariatric surgery in obese patients in the state of Paraná. Methods: longitudinal and retrospective study, conducted between January 2010 and December 2013, with 737 patients of both sexes submitted to RYGB or SG and evaluated in the preoperative, 1 and 5 years after bariatric surgery (BS). Age, height, body weight, Body Mass Index (BMI), biochemical and pressure parameters were recorded. Results: of the total of patients, men represented lower frequency, were slightly older, with higher body weight, BMI and worse metabolic and pressure conditions than women in pre-BS (p<0.05). Regardless of sex, RYGB and SG were effective in promoting body weight reduction and BMI in 1 and 5 years after BS; the RYGB technique had greater impact on these variables in both sexes (p<0.05). The highest percentage of lost weight was observed in women who underwent the RYGB technique in the first year after BS. Five years after BS, the RYGB technique promoted a higher rate of body weight reduction in men and women compared to the SG technique (p<0.05). Conclusion: regardless of sex, the RYGB technique promotes a higher degree of body weight reduction and BMI over time compared to the SG; having its biggest impacts in the 1 year after BS, especially in women.
Human rights violations in normalizing procedures on intersex children
Authors: Leivas Paulo Gilberto Cogo , Schiavon Amanda de Almeida , Resadori Alice Hertzog , Vanin Aline Aver , Almeida Alexandre do Nascimento , Machado Paula Sandrine
Published: February 2023

Intersex children in Brazil are still subjected to “normalizing” surgical procedures and subsequent bodily interventions to make their bodies conform to binary views of sex. Resolution n. 1,664/2003 of the Brazilian Federal Council of Medicine legitimizes interventions upon intersex bodies, being the only national normative instrument that address the subject. However, the demands of international intersex political activism have denounced how early childhood interventions for sex designation mutilate children’s bodies and violate a number of human rights. This research discusses how early, irreversible, and normalizing procedures performed without the intersex person’s consent are human rights violations. Based on the concept of epistemic (in)justice, we first look at the disputes surrounding the evidence that underpin medical practices. We demonstrate how such procedures violate human rights to health, body integrity, autonomy, and sexual and reproductive rights, analyzing which strategies were put into place to prevent them. We propose that intersex people be at the center of decisions regarding their bodies, that non-surgical paths be discussed with patients and their family members, and that early, invasive, mutilating, harmful, cosmetic, and unconsented surgical interventions on intersex children be prohibited. Guiding tools must introduce changes into its regulatory bias to, from an interdisciplinary perspective, include bioethical and human rights bodies, as well as intersex activists.
Violações de direitos humanos nos procedimentos normalizadores em crianças intersexo
Authors: Leivas Paulo Gilberto Cogo , Schiavon Amanda de Almeida , Resadori Alice Hertzog , Vanin Aline Aver , Almeida Alexandre do Nascimento , Machado Paula Sandrine
Published: February 2023

No Brasil, crianças intersexo ainda são submetidas a procedimentos para designação de sexo binário no nascimento e a intervenções corporais subsequentes. A Resolução nº 1.664/2003, do Conselho Federal de Medicina, legitima intervenções sobre as corporalidades intersexo, se constituindo como o único instrumento normativo nacional que trata sobre o tema. No entanto, as demandas advindas do ativismo político internacional intersexo vêm expondo o quanto as intervenções precoces na infância para a designação de um sexo binário mutilam os corpos das crianças e violam uma série de direitos humanos. Esta pesquisa visa identificar como os procedimentos precoces, irreversíveis e normalizadores, realizados sem o consentimento da pessoa intersexo, revelam-se violadores de direitos humanos. Sob as lentes do conceito de (in)justiça epistêmica, partimos das disputas em torno da produção de evidências que embasam as práticas médicas. Demonstramos como esses procedimentos violam os direitos humanos à saúde, à integridade corporal e à autonomia e os direitos sexuais e reprodutivos, e analisamos quais têm sido as estratégias para evitar essas violações. Propomos que pessoas intersexo estejam no centro das decisões sobre o próprio corpo e que sejam debatidos, junto a pacientes e familiares, caminhos não cirúrgicos e proibidas intervenções precoces, invasivas, mutilatórias, prejudiciais, cosméticas e não consentidas nos corpos de crianças intersexo. A proposição de mudanças em instrumentos norteadores que deixem de regular esses corpos é necessária para, a partir de uma perspectiva interdisciplinar, incluir instâncias bioéticas e de direitos humanos, assim como pessoas do ativismo político intersexo.
Acessibilidade e disponibilidade de oferta para o cuidado ao hipertenso na atenção primária à saúde em município rural remoto, Amazonas, Brasil, 2019
Authors: Silva Amanda Marinho da , Fausto Márcia Cristina Rodrigues , Gonçalves Maria Jacirema Ferreira
Published: February 2023

Estudo de caso único com objetivo de compreender o acesso à atenção primária à saúde (APS) em relação à acessibilidade geográfica e disponibilidade em um município rural remoto do Amazonas, Brasil, para o cuidado à saúde voltado ao controle da hipertensão arterial sistêmica. Realizou-se a análise temática como método de interpretação do conteúdo das 11 entrevistas semiestruturadas realizadas com gestores municipais, profissionais da APS e usuários hipertensos. A acessibilidade geográfica está condicionada à mobilidade fluvial, disponibilidade de transporte, condição financeira dos usuários para deslocamento e presença dos serviços nas comunidades ribeirinhas. Na disponibilidade, a existência de profissionais de saúde, medicamentos, equipamentos e a integração da APS com a Rede de Atenção à Saúde refletem na oportunidade de diagnóstico e acompanhamento dos hipertensos. Não obstante o acesso à saúde seja mais complexo, as dimensões avaliadas mostram fragilidades exacerbadas pelo contexto marcado por disparidades socioespaciais e ausência de políticas públicas, comprometendo a garantia do direito à saúde.
Characterization of coccidiosis and evaluation of suggestive cases of subclinical necrotic enteritis in broilers
Authors: Santiani Fabio , Silva Rodrigo Otávio S. , Oliveira Júnior Carlos Augusto de , Withoeft Jéssica Aline , Cristo Thierry G. , Costa Leonardo S. , Gaspar Taís , Casagrande Renata A.
Published: February 2023

ABSTRACT: This study performed the characterization of coccidiosis in broilers and evaluated the occurrence of suggestive cases of necrotic enteritis (NE), seeking if there is an association between the diseases in Brazilian flocks. Two hundred and fifty-six birds from 32 flocks were evaluated. Macroscopic and histopathological lesions were graduated for coccidiosis and NE. Intestinal content was investigated by polymerase chain reaction (PCR) for seven species of Eimeria and by selective anaerobic culture for Clostridium perfringens and identification of the NetB gene. Flocks positive for coccidiosis represented 93.8%. Macroscopic lesions of coccidiosis were Grade 1 for E. acervulina (27%); E. tenella (9.7%) and E. maxima (8.9%). Histopathological evaluation showed Grade 1 in duodenum (38.2%); jejunum (21.4%); cecum (9.3%) and ileum (5%). PCR demonstrated positivity for E. tenella (21.9%), E. maxima (18.8%), and E. acervulina (3.1%). Suggestive macroscopic lesions of necrotic enteritis ranged from Grade 1 (16%), 2 (23%) and 3 (10,9%). Histopathology indicated the absence of necrosis, showing only hemorrhage in the mucosa and submucosa, with the presence of Eimeria spp. Clostridium perfringens type A netB+ was not isolated, demonstrating that macroscopic lesions found mostly in the jejunum did not characterize NE, based on histopathology and negativity of the NetB gene. The study suggests that, due to the high occurrence of coccidiosis, many macroscopic findings suggestive of NE are, in fact, attributed to atypical lesions caused by the reproduction of Eimeria spp.
Efeitos da suplementação com vitaminas C e E na resposta inflamatória aguda em Piaractus mesopotamicus
Authors: Bozzo Fabiana Rizzo , Claudiano Gustavo da Silva , Yunis-Aguinaga Jefferson , Marcusso Paulo Fernandes , Engrácia Filho Jair Rodini , Moraes Julieta Rodini Engrácia de
Published: February 2023

Resumo As vitaminas C e E são potentes antioxidantes que reduzem os efeitos nocivos do estresse em várias espécies, incluindo peixes. Neste estudo, avaliou-se o efeito das vitaminas C, E e sua combinação na aerocistite aguda induzida por Aeromonas hydrophila inativada em pacu. 288 peixes foram distribuídos em 4 grupos suplementados por 90 dias: G1-controle; G2-suplementado com 500 mg de Vitamina C; G3-suplementado com 500 mg de Vitamina E; G4-suplementado com 500 mg de Vitamina C + 500 mg de Vitamina E. Os peixes foram divididos em três grupos, o primeiro não foi inoculado; o segundo foi inoculado na bexiga natatória com 3 x 109 UTC de A. hydrophila inativada e a última com soro fisiológico. O exsudato inflamatório foi coletado da bexiga natatória para avaliação do componente celular e citoquímica. Os resultados mostraram maior acúmulo de leucócitos nos peixes inoculados com a bactéria. A citoquímica foi eficaz na identificação de trombócitos, linfócitos, macrófagos e granulócitos presentes no exsudato. Também foi observado que os peixes que receberam suplementação com vitaminas apresentaram maior acúmulo de células totais no exsudato com predominância de linfócitos e trombócitos. Esses resultados sugeriram que a suplementação com vitaminas melhorou as respostas imunológicas.
Tétano em um canino: aspectos clínicos e terapêuticos
Authors: Silva Gabriela Pereira da , Garcia Cinthia , Silva Rúbia Schallenberger da , Klaser Bruno Webber , Arenhart Sandra , Menin Álvaro , Lima Andressa Antunes de , Padilha Vanessa Sasso
Published: February 2023

Resumo O tétano é uma doença grave e rara em pequenos animais, de caráter agudo e mediada pela ação da neurotoxina tetanospasmina, proveniente do bacilo Clostridium tetani. Neste relato descreve-se um caso de tétano em um canino, com ênfase em seus aspectos clínicos e terapêuticos, além da sua recuperação clínica. Foi atendido no Hospital Veterinário da Universidade de Passo Fundo, um canino, fêmea, da raça Pitbull, com cinco meses, em status epilepticus. Após a estabilização da paciente, constataram-se animal em posição de cavalete, com paralisia espástica generalizada, risus sardonicus, trismo, cauda e orelhas eretas e dificuldade em expandir o tórax. O diagnóstico presuntivo de tétano foi firmado a partir da anamnese, sinais clínicos e achados laboratoriais. O tratamento suporte estabelecido incluiu reposição hidroeletrolítica, soro antitetânico, antibioticoterapia, analgesia, fármacos miorrelaxantes e anticonvulsivantes. O manejo intensivo da paciente foi realizado com sondagem uretral e nasoesofágica, trocas de decúbito a cada duas horas e diminuição de estímulos ambientais. A fisioterapia e a acupuntura também foram utilizadas para complementar o tratamento e acelerar a recuperação. A paciente recebeu alta médica um mês após o início do tratamento, apresentando evolução satisfatória. No presente caso, o exame clínico em associação aos sinais clínicos característicos da doença, acrescidos da anamnese minuciosa foram fundamentais ao diagnóstico presuntivo de tétano. Além disso, o manejo intensivo, o tratamento medicamentoso, assim como a realização de fisioterapia e acupuntura, possibilitaram a evolução do quadro clínico à cura.
Fontes lipídicas vegetais na alimentação de codornas japonesas em fase de recria e sua repercussão na fase inicial de produção
Authors: Valentim Jean Kaique , Garcia Rodrigo Garófallo , Burbarelli Maria Fernanda de Castro , Komiyama Cláudia Marie , Serpa Felipe Cardoso , Caldara Fabiana Ribeiro , Mendes Janaína Palermo , Pietramale Rita Therezinha Rolim , Barbosa Deivid Kelly , Albino Luiz Fernando Teixeira
Published: February 2023

Resumo A pesquisa foi conduzida com objetivo de avaliar o efeito residual de diferentes fontes lipídicas na dieta de codornas japonesas (Coturnix japonica) na fase de recria sob o desempenho e a qualidade de ovos na fase inicial de postura. Na primeira etapa foram utilizadas 400 codornas japonesas com idade de 21 dias, as aves foram distribuídas em tratamentos seguindo um delineamento inteiramente casualizado com dez repetições, de oito aves, em cinco tratamentos: ração basal (RB) com 2,5% de óleo de soja, RB com 2,5 % de óleo de milho, RB com 2,5% de óleo algodão, RB com 2,5% de óleo de girassol e RB com 2,5% de óleo de canola. Aos 42 dias mantendo o delineamento inicial, todas aves receberam ração basal com óleo de soja, para que fosse avaliado o efeito residual da fase anterior sobre o desempenho e a qualidade dos ovos na fase inicial de postura (43 - 84 dias). As diferentes fontes lipídicas não afetaram o desempenho das aves na fase inicial de produção. Para a qualidade dos ovos, os parâmetros de altura, diâmetro e índice de gema, gravidade e UH foram melhores no tratamento com utilização de óleo de girassol. Houve efeito residual da utilização de fontes lipídicas de origem vegetal na dieta em fase de recria de codornas japonesas sobre as características da qualidade dos ovos. As fontes lipídicas oriundas das sementes de soja, milho, algodão, canola e girassol podem ser utilizadas como ingredientes energéticos na dieta de recria de codornas poedeiras por nâo serem prejudiciais ao desempenho inicial das aves. A longevidade na produção dos ovos das aves alimentadas com diferentes fontes lipídicas na fase de recria foi semelhante.
Yacon juice as culture and cryoprotectant medium for Latilactobacillus sakei and Staphylococcus vitulinus autochthonous strains
Authors: Palavecino Prpich Noelia , Sanabria Ernesto , Gliemmo María Fernanda , Cayré María Elisa , Castro Marcela Paola
Published: February 2023

Abstract Yacon is mainly constituted of water and carbohydrates [single sugars and fructooligosaccharides (FOS)], thus being an excellent alternative for the growth and preservation of bacterial culture. Latilactobacillus sakei ACU-2 and Staphylococcus vitulinus ACU-10 comprised the autochthonous starter culture SAS-1 designed for the manufacture of dry sausages. This study evaluated the use of yacon juice as a potential growth medium and cryoprotectant for these bacteria. The growth medium was prepared with yacon juice supplemented with peptone and dipotassium phosphate. After growing, cells were resuspended in yacon juice (5, 10 and 25 mL/100 mL) and lyophilized. Viable cells were count before, immediately after lyophilization, and along 6 months of refrigerated storage. Both bacteria grew in every yacon concentration tested; however, juice concentration affected their growth. Latilactobacillus sakei grew at μ = 0.256 ± 0.01 giving the highest bacterial density at 10 mL/100 mL (Log DOmax 0.33 ± 0.01). While 5 mL/100 mL yacon juice provided the best conditions for S. vitulinus growth (μ = 0.215 ± 0.016; Log DOmax 0.32 ± 0.01). After lyophilization, the survival rate was 91.1% for L. sakei and 65.8% for S. vitulinus. Throughout storage, high cell counts suggested good stability of both bacteria. Results revealed that yacon juice comprises a nutritive substrate for the growth and cryopreservation of tested strains from the genus Latilactobacillus and Staphylococcus.
Genetic and phenotypic profile of Fabry disease in the population of Vale do Paraiba and Eastern São Paulo
Authors: Paz Osvaldo Theodoro da , Lacerda Rosiane Cássia Teixeira , de Andrade Luis Gustavo Modelli
Published: February 2023

ABSTRACT Introduction: Fabry disease (FD) is an inborn error of metabolism characterized by α-galactosidase A deficiency. The primary objective was to evaluate the genetic and phenotypic profile of Fabry disease in hemodialysis. Methods: Observational cohort study to determine the incidence of genetic variations and phenotypic changes for FD in hemodialysis patients in the Paraiba Valley and Eastern São Paulo. Genetic testing for the GLA gene was performed for men and women over 12 years of age at the hemodialysis clinics between January 2016 and December 2019 as a screening protocol. Results: The cases came from screening exams of the index case among patients with chronic kidney disease, resulting in 17 families and totaling 82 patients under study. The classification of the most prevalent variant was that of uncertain significance (54%), followed by the pathogenic variant (46%). Five patients in two families were described with two types of variants not previously described in the literature, with pathogenic behavior. Comparing the types of variants, the presence of a pathogenic variant was associated with higher levels of lysoGB3, lower values for alpha-GAL activity and higher frequency of symptoms related to FD. Conclusion: We characterized an extensive population of patients with FD variants with rich genetic, clinical and biomarker details. We believe that this study can help to better characterize the Brazilian population with FD and the most frequent types of variants.
Perfil genético e fenotípico da doença de Fabry na população do Vale do Paraíba e Zona Leste de São Paulo
Authors: Paz Osvaldo Theodoro da , Lacerda Rosiane Cássia Teixeira , de Andrade Luis Gustavo Modelli
Published: February 2023

RESUMO Introdução: A doença de Fabry (DF) é um erro inato do metabolismo caracterizado pela deficiência da enzima α-galactosidase A. O objetivo primário foi avaliar o perfil genético e fenotípico da doença de Fabry em hemodiálise. Métodos: Estudo de coorte observacional para determinar a incidência de variações genéticas e alterações fenotípicas para DF em pacientes em hemodiálise no Vale do Paraíba e Zona Leste de São Paulo. O teste genético para o gene GLA foi realizado para homens e mulheres em todos os pacientes das clínicas de hemodiálise maiores de 12 anos entre janeiro de 2016 a dezembro de 2019 como protocolo de rastreio. Resultados: Os casos foram provenientes de exames de triagem do caso índice entre pacientes portadores de doença renal crônica, resultando em 17 famílias e totalizando 82 pacientes em estudo. A classificação da variante mais prevalente foi a de significado incerto (54%), seguida da variante patogênica (46%). Foram descritos 5 pacientes em duas famílias com dois tipos de variantes ainda não previamente descritos na literatura com comportamento patogênico. Na comparação entre os tipos de variantes, a presença de variante patogênica foi associada a maiores níveis de lysoGB3, menores valores da atividade da alfa-GAL e maior frequência de sintomas relativos à DF. Conclusão: Caracterizamos uma extensa população de pacientes com variantes para DF com riqueza de detalhes de genética, clínica e de biomarcadores. Acreditamos que este estudo possa auxiliar na melhor caracterização da população brasileira com DF e nos tipos mais frequentes de variantes.
Acknowledgments in thesis and dissertations in the area of Education: a little bit of me, a little bit of us
Authors: Ferreira Luciana Haddad , Aguiar Thiago Borges de , Bollis Renata Augusta Ré
Published: February 2023

ABSTRACT In this paper, we discuss the writing of acknowledgments in thesis and dissertations in education. We selected a sample of texts from five postgraduate programs at public universities, one in each region of Brazil. We read them using an evidential method, starting from the autobiographical and narrative character of this type of writing. We found aspects related to religiosity; affective and family relationships; coexistence with the supervisor, professors, and university employees; bonds of friendship and collegiality; and support from development agencies. We also pointed to recognition of difficulties and persistence in research and writing; thanksgiving as a formality, irony, or protest strategy; the reflection of the journey and; the perception of the formative process itself. We conclude with the political character of the acknowledgment writing, on social commitment to the production of knowledge, as well as the collective and humanizing process of investigative work in education.
Neurociência e aprendizagem
Authors: Costa Raquel Lima Silva
Published: February 2023

RESUMO De enfoque teórico, o presente artigo apresenta noções da neurociência, como neuroplasticidade e funções nervosas superiores (atenção, memória, motivação, emoções e funções executivas), estabelecendo relações entre elas e a aprendizagem. Assim, a partir de revisão de literatura e síntese das informações, temos por principal objetivo articular as contribuições da neurociência às práticas pedagógicas. Ao fazê-lo, esperamos contribuir para reflexões voltadas à promoção de aprendizagens ainda mais significativas aos estudantes.
A gymnastica no Collegio de Pedro II: uma prática compartilhada pelos seus mestres
Authors: Romão Anna Luiza Ferreira , Avelar Ana Claudia , Moreno Andrea
Published: February 2023

Resumo Este estudo tem como fio condutor a circulação, pelo Rio de Janeiro da segunda metade do século XIX, de três mestres de gymnastica: Paulo Vidal, Vicente Casali e Arthur Higgins. Ao trazê-los para o centro desta história, temos como objetivo compreender, a partir de suas trajetórias, qual gymnastica foi por eles forjada e, ao mesmo tempo, compartilhada no Collegio de Pedro II no decorrer dos anos oitocentistas. Nossa hipótese é que o trânsito e a atuação em variadas e distintas instituições contribuíram de forma significativa com o processo de sistematização da gymnastica naquele colégio. Para tanto, além de analisarmos os programas de ensino por eles elaborados, faremos um cruzamento com demais fontes e dados obtidos nos jornais da época, que nos permitem identificar não só as instituições pelas quais circularam, mas também elementos constitutivos dessa prática corporal. Como conclusões, destacamos que, no processo de sistematização da gymnastica no Pedro II, ocorreram negociações e partilhas entre seus mestres, os quais, para que a gymnastica fosse legitimada, lançaram mão de diferentes elementos obtidos nas instituições escolares e não escolares pelas quais circularam. Assim, ao verificarmos que a prática de ginástica fez parte do percurso formativo do Collegio de Pedro II, não podemos afirmar que se tratou de uma única gymnastica. Diante disso, as gymnasticas forjadas e compartilhadas pelos três professores estiveram encarnadas em suas experiências e trajetórias, e, por isso, comportavam uma dimensão transformativa que se adequava ao tempo e ao espaço em que eram conformadas.
Prevalence of sexual initiation and associated factors in school adolescents in Piauí, Brazil, 2015
Authors: Castro Lucélia da Cunha , Viana Vera Alice Oliveira , Rufino Andréa Cronemberger , Madeiro Alberto Pereira
Published: February 2023

Abstract Objective: to analyze prevalence of sexual initiation and associated factors in adolescents in Piauí. Methods: this was a cross-sectional study, with secondary data from the 2015 National Adolescent School-based Health Survey. Hierarchical analysis was performed using robust Poisson regression. Results: a total of 3.872 adolescents were interviewed. Prevalence of sexual initiation was 24.2%; risk factors for sexual initiation were being male [prevalence ratio (PR) = 2.18; 95% confidence interval (95%CI) 1.90;2.47], being 15 years old or over (PR = 2.49; 95%CI 2.18;2.76), living with mother (PR = 0.68; 95%CI 0.54;0.82), working (PR = 1.82; 95%CI 1.55;2.10), attending a public school (PR = 1.39; 95%CI 1.09;1.75), practicing bullying (PR = 1.50; 95%CI 1.31;1.72), using alcohol (PR = 2.35; 95%CI 2.09;2.64), using cigarettes (PR = 1.46; 95%CI 1.22;1.70) and using illicit drugs (PR = 1.40; 95%CI 1.15;1.66). Conclusion: prevalence of sexual initiation was high and associated with sociodemographic characteristics and vulnerable health behaviors, indicating the need for health promotion strategies.
Influência da desigualdade socioeconômica na distribuição das internações e dos óbitos por covid-19 em municípios brasileiros, 2020: um estudo ecológico
Authors: Silva Gabriela Drummond Marques da , Souza Anelise Andrade de , Castro Mônica Silva Monteiro de , Miranda Wanessa Debôrtoli de , Jardim Leticia Lemos , Sousa Rômulo Paes de
Published: February 2023

Resumo Objetivo analisar a influência da desigualdade socioeconômica na distribuição da covid-19 nos maiores municípios brasileiros (> 100 mil habitantes), controlando, pelo efeito da infraestrutura hospitalar, comorbidades e outras variáveis. Métodos estudo ecológico sobre internações e óbitos por covid-19 em 2020; dados de desfecho obtidos do Ministério da Saúde; a razão de incidência foi estimada via modelo linear generalizado. Resultados identificados 291.073 internações e 139.953 óbitos; encontrou-se maior taxa de mortalidade nos municípios com maior população não branca (IC95% 1,01;1,16) e nos domicílios com mais de duas pessoas por cômodo (IC95% 1,01;1,13); para ambos os desfechos, esgotamento sanitário foi protetivo (internações: IC95% 0,87;0,99 – óbitos: IC95% 0,90;0,99), e população em aglomerados subnormais revelou-se fator de risco (internações: IC95% 1,01;1,16 – óbitos: IC95% 1,09;1,21) com interação, com a proporção de pessoas a receber auxílio emergencial (internações: IC95% 0,88;1,00 – óbitos: IC95% 0,89;0,98). Conclusão condições socioeconômicas afetaram o adoecimento e morte por covid-19 no Brasil.
AN ASYMPTOTIC ELECTROSTATIC MODEL OF AN ARRAY OF MICROMIRRORS
Authors: Trinh Nguyen-Nhat-Binh , Lenczner Michel
Published: February 2023

This paper discusses a multiscale electrostatic model of a two-dimensional micromirror array. It is applicable to very large arrays with several zones of electrical actuation. The model is made with periodic solutions and four kinds of boundary layer effects at outer boundaries, interfaces between different actuation zones, and outer and inner edges. This work is done in the context of the development of a symbolic calculation software based on an extension-combination principle, so that the model derivations are constructed in such a way as to follow the same algorithm.