bluuebunny/crossref_metadata_2025 huggingface dataset:
OBSTACLES TO ATTRACTING FOREIGN INVESTMENT TO UKRAINIAN TERRITORIAL COMMUNITIES: ANALYSIS AND SOLUTIONS
Authors:   Admiral Makarov National Shipbuilding University, Filipishyna Liliya
Published: November 2024

The article is devoted to the analysis of the main obstacles that hinder the attraction of foreign investments in
Ukrainian territorial communities and suggests effective ways to overcome them. Given the current state of the
Ukrainian economy, attracting foreign capital can play a key role in the development of territorial communities,
stimulating economic growth, creating jobs, and improving the socio-economic environment. However, a number of
factors, such as political instability, imperfect legislative regulation, corruption, and bureaucracy, limit the possibilities
for effectively attracting investments. The article analyzes these barriers and proposes a set of measures to overcome
them, including reforming the legal framework, simplifying administrative procedures, developing infrastructure, and
strengthening institutional mechanisms to support investors. Additionally, the article emphasizes the importance of a
transparent and investor-friendly regulatory environment that would provide foreign investors with clear and consistent
rules for doing business in Ukraine. The need for an efficient legal system that ensures the protection of property
rights and the enforcement of contracts is underscored as crucial for building investor confidence. Furthermore,
the article highlights the importance of reducing corruption and improving governance at all levels, especially in
local authorities, which directly interact with potential investors. Recommendations include implementing digital
platforms for administrative procedures to reduce personal contact with officials, thereby minimizing corruption risks.
The establishment of transparent procedures and accountability mechanisms within local governments is also
advised to foster a culture of trust between the authorities and investors. The proposed measures aim not only to
attract foreign capital but also to ensure its effective utilization for sustainable development. The article concludes
that, through strategic reforms and targeted efforts, Ukraine’s territorial communities could become attractive hubs
for foreign investment, which would ultimately lead to economic growth, improved living standards, and social
stability across the regions.
METHODS OF IMPROVING THE CORPORATE CULTURE OF THE ORGANIZATION AS A FACTOR OF STRATEGIC DEVELOPMENT OF INNOVATIVE ACTIVITY
Authors:   Cherkasy branch of Private Higher Educational Establishment  “European University”, Andrushkevych Nataliia , Yefimovskyi Oleksii ,   Private Higher Educational Establishment “European University”, Taranenko Oleksandr ,   Private Higher Educational Establishment “European University”
Published: November 2024

There is an opinion that corporate culture is formed independently and spontaneously in connection with the influence of various values of employees, partners from the production chain, customers, and the environment. But as a result of the uncontrolled creation of corporate culture, its inconsistency with business goals and the innovative strategy of the organization is possible. The most effective purposeful creation of corporate culture. In this case, the rules and principles governing relations in the organization must be formulated in writing and binding on all employees, regardless of position and status. Corporate culture refers to effective tools of business development strategy and creates the image of the organization. Its creation is focused on the growth of competitiveness and is related to innovations aimed at the business goals of the organization. Corporate culture exists in any organization, regardless of the presence of a separate division under this name. Specialized management of corporate culture provides an opportunity to develop the organization’s business. Such an organization will have weight and appeal to shareholders, business partners and future employees. The article examines the issue of creating a corporate culture as a tool of strategic innovative development of the organization aimed at increasing the competitiveness of the organization. The corporate culture of the organization determines the vector of its development, makes it possible to adjust the issue of personal goals with the goal of the organization, creates a common cultural space that includes norms, values and behavioral models agreed with all employees. Corporate culture can have a greater impact on an organization’s success than other factors. Strong corporate cultures develop rational decision-making, form a basis of cooperation based on trust, informally influence young employees, developing their personal and professional qualities. The scale of corporate culture is determined by the stability and number of the most important views and beliefs accepted by employees. Cultures with many degrees of beliefs and values significantly influence behavior in an organization. Some cultures have clearly shared values, beliefs and beliefs held by employees.
МОРАЛЬНО-ДУХОВНІ ЧИННИКИ РОЗБУДОВИ НЕЗАЛЕЖНОЇ УКРАЇНСЬКОЇ ДЕРЖАВИ В ПОГЛЯДАХ В. К. ЛИПИНСЬКОГО
Authors: Бортніков Валерій , Бортнікова Алла
Published: November 2024

Розглянуто погляди вітчизняного історика та політолога, представника консервативного напряму української суспільно-політичної думки В. К. Липинського щодо морально-духовних чинників та ролі національної аристократії у творенні незалежної Української держави та нації. Розкрито його бачення генетичного зв’язку держави та нації, провідної ролі еліти в їх розбудові. Акцентовано увагу на принциповій важливості в процесах будівництва нації першочерговості створення інституту держави над питаннями сфери культури. Розкрито проблему засад інтегрування до української нації національних меншин. Концептуальну модель української нації вчений розумів як об’єднання всіх національних спільнот, які проживають на теренах держави, за принципом почуття територіального патріотизму, а не етнічної належності. Тобто шлях розбудови незалежної, суверенної держави та нації мислитель бачив на шляху добровільного об’єднання всіх громадян, які спільно проживають на одній території. Критерієм відмінності понять «патріотизм» і «шовінізм», що є різновидами націоналізму, провідник українського націєтворення вважав ставлення до держави з точки зору їх державотворчого (патріотизм) або руйнівного (шовінізм) потенціалу. Здійснено аналіз міркувань мислителя над проблемою шляхетності й аристократизму, брак яких він вбачав у тогочасній українській еліті. Учений аргументовано доводив, що без існування незалежної держави майбутнє української нації залишатиметься під загрозою, а тому пропонував провідним верствам об’єднатися і зосередити зусилля на розбудові української держави. Погляди В. К. Липинського щодо перспектив розбудови національної держави базуються на ідеї територіального патріотизму, де ключову роль у національно-державному будівництві мають грати чинники єдності, високої моралі та духовності, а не етнічної належності. Водночас для збереження власної ідентичності та самобутності українського народу надзвичайно важливим є збереження, захист і поширення української мови та культури.
КОНЦЕПТУАЛЬНІ ЗАСАДИ НАУКОВИХ ДОСЛІДЖЕНЬ ПРОБЛЕМ УПРАВЛІННЯ ПІДПРИЄМСТВАМИ МАЛОГО БІЗНЕСУ В УМОВАХ ЦИФРОВІЗАЦІЇ
Authors: Зачосова Н.В. , Липа А.О.
Published: November 2024

Конкретизовано напрями управління підприємствами малого бізнесу, які дозволять забезпечити їх адаптацію до тенденцій цифровізації економічного простору. До їх переліку внесено: цифровий фінансовий менеджмент; стратегічний менеджмент цифрового розвитку; дистанційне та гнучке управління персоналом; управління цифровими ризиками діяльності малих підприємств; управління цифровою та інформаційною безпекою малого бізнесу; менеджмент дистанційного обслуговування клієнтів; цифрове діловодство та ведення документації за результатами бізнесу у цифровому середовищі; управління цифровими комунікаціями; планування підприємницької діяльності за оптимістичним, реалістичним і песимістичним сценарієм; управління фінансово-економічною безпекою у цифровому середовищі; управління цифровізацією бізнес-процесів підприємства. Встановлено, що концептуальні засади наукових досліджень проблем управління підприємствами малого бізнесу в умовах цифровізації полягають у: поєднанні зарубіжного досвіду управління малим бізнесом із вітчизняними реаліями ведення підприємницької діяльності; концептуалізації безпеко орієнтованого управління малим бізнесом; запровадження концепції людиноцентризму у механізм управління персоналом малих підприємств; побудові «цифрового підприємства» як середовища реалізації цифрових бізнес-процесів у щоденній діяльності суб’єктів господарювання.
The Ideological Ambiguity and Actual Outcome of the New Poor Law of 1834
Authors:   Korea Association of World History and Culture, Kang Myung-Su
Published: November 2024

This paper seeks to trace the ideological trends surrounding the enactment of the New Poor Law and explore the essence of the act itself and the changes it brought about. The Swing Riots of 1830 sparked a substantial demand for reforming poor laws, resulting in the organisation of the Royal Commission into the Operation of the Poor Laws. Edwin Chadwick, a Benthamite, and Nassau Senior, a liberal political economist, played key roles in leading the compilation of the final report of the commission that served as the foundational material for the New Poor Law. Their divergent ideological orientations translated into the dual nature of the act. Utilitarian Benthamites prioritised expanding government functions, the growth of bureaucracy, and the restructuring and rationalisation of administrative structures as needed. On the other hand, advocates of classical liberalism, who championed laissez-faire, emphasized minimizing government intervention, local autonomy, and economic individualism. The specific legal provisions of the New Poor Law and the socio-economic changes following its enactment were an exquisite compromise between these two ideologies. According to the act, a central authority specialising in poor administration was established. Locally, the parish-based Old Poor Law system was dismantled, and poor law unions took the place of parishes, establishing large joint workhouses. These structural changes clearly aligned with the direction pursued by the Benthamites. At the same time, in specific matters, the New Poor Law, however, embodied elements of classical liberalism. The newly established central authority performed only a passive supervisory role, and the operation of local unions still remained under the influence of local elites. The ultimate goal of the union workhouses was not the expected rehabilitation of or care for the poor but rather a deterrent effect. In conclusion, the 19th-century New Poor Law system encapsulated elements of classical liberalism within the Benthamite framework.
Materialised Ideology: Approaching Baekje’s Kingly Ideal through King Muryeong’s Tomb
Authors:   Korea Association of World History and Culture, Sebastian Müller Sebastian Müller
Published: November 2024

The tomb of King Muryeong and his consort is one of the most important archaeological sites on the Korean Peninsula. Despite a haphazardly carried out excavation and other problems, the information that can be gathered through analyses of the tomb architecture, the style and shape of the artefacts as well as their distribution within the tomb are manifold. The present study discusses the grave in its entirety from the viewpoint of materialised ideology, elite distinction and the royal self-portrayal, in short the kingly ideal of the Baekje kingdom at the beginning of the sixth century. One aspect of Muryeong’s tomb stands out, namely the strong presence of foreign elements such as the tomb architecture, objects and even rituals. Remarkable is also the high degree of craftsmanship that can be observed in the tomb construction and on most artefacts. The present article draws on cultural- anthropological concepts such as esoteric knowledge and the connection between skilled crafting and authority. It is argued that the reference to foreign customs and objects was part of Baekje’s state ideology, a means to distinguish the royal family from the commoners and to justify the elevated position of the royal lineage. Outstandingly crafted items were part of this behavior of distinction. The possession and display of those items was a necessity to grant authority to the king and his successors.
Study on the Cultural Exchange of Korean and Chinese Calligraphy in the 17th Century: Focusing on Envoys
Authors:   Korea Association of World History and Culture, Son Han-Bin
Published: November 2024

This study examines the content and significance of cultural exchanges in calligraphy between the Joseon Dynasty in the 17th century and the Ming and Qing dynasties, focusing on Envoys. Through a review of the exchange content, four forms were identified: ‘exchange of literati networks’, ‘exchange of calligraphy works’, ‘appreciation of calligraphy works’, and ‘sale of calligraphy works.’ Based on these exchange activities, three significances were derived: ‘relevance to external relations’, ‘external status of Joseon's calligraphy culture’, and ‘influence on Joseon's calligraphy culture.’ Joseon engaged in calligraphy cultural exchanges with the Ming and Qing through Envoys, and the influx of new calligraphy materials had both significant and subtle impacts on the flow of Joseon's calligraphy culture. Furthermore, it is noted that the materials related to these exchanges have not been systematically organized. For these reasons, ongoing research is deemed necessary to elucidate the content and significance of calligraphy exchanges.
Establishment of Orphanage Affiliated Organization and Infant Relief during the Qing Dynasty : Focusing on Cases in the Jiangsu Region
Authors:   Korea Association of World History and Culture, Yoo Chae-Wen
Published: November 2024

In recent years, in understanding the Qing Dynasty in the first half of the 19th century, attempts have been made to criticize the existing research trend that focuses on the decline and to examine the changes and historical implications of the time through more diverse and in-depth research on this period.
These studies can suggest a new interpretation of this period by examining various patterns of change in the first half of the 19th century. he retreat of the state at the end of the Qing Dynasty or the rise of the local elite is a continuation of the trend that began before that period, rather than an immediate result of the 'many difficulties and worries inside and outside the country' in the mid-19th century.
One of the lack of accumulation of research in the various aspects of change is the relief work. In particular, the orphanage project during the Qing Dynasty was in the realm of representative charity that coexisted between the state and society, and it changed professionally and independently, such as functional differentiation as the types of charitable facilities diversified due to the social mobilization of local elites. Nevertheless, the formation and change of these public spheres during the Qing Dynasty were characterized only by inertia or understood as a historical situation filled with a traditional order without an exit.
Instead of simplifying the form of charity in the private sector before modern times and contrasting it with modern changes, this paper reveals that the expansion of the public role of local elites has continued since pre-modern times, and that private-led orphanage projects have sufficient potential social capabilities.
Advanced Disease Detection and Personalized Medicine: Integrated Data Approaches for Enhanced Parkinson's Disease and Breast Cancer Detection and Treatment in the USA
Authors: Bishnu Padh Ghosh  , Proshanta Kumar Bhowmik  , Mohammad Shafiquzzaman Bhuiyan
Published: November 2024

This present study focuses on integrating data-driven approaches into personalized medicine for better detection and treatment of Parkinson's disease and breast cancer through the US healthcare system. The deeper integration of genomics, clinical records, and patient self-reported data with machine learning algorithms will enhance early disease detection and optimization of treatment pathways. The results show that, more precisely, Random Forest and XGBoost machine learning models hold great promise for considerably improving diagnostic precision and predictive power. This realization opens a door for precision medicine-tailored health services according to the peculiarities of individual patients, which would improve treatment outcomes and encourage preventive healthcare. In addition, this approach aligns with the latest US efforts in precision medicine and contributes to evidence-based transformation in healthcare practice.
Рудеральні каймові угруповання Calamagrostis epigejos і Rubus caesius
Authors: Пашкевич Н.А. , Фіцайло Т.В.
Published: November 2024

Стаття присвячена вивченню рудеральних угруповань, сформованих Calamagrostis epigejos та Rubus caesius, приурочених до ділянок з відносно бідними легкими ґрунтами, що утворюють бордюри між лісовими, трав’яними ценозами та комунікаційними шляхами. Трав’яний покрив досліджених угруповань досить строкатий, сформований рудеральними, лучними та узлісними видами. Було виділено дві асоціації Rubo сaesii-Calamagrostietum еpigeji та Elymo repentis-Rubetum caesii, які відносяться до союзу Convolvulo arvensis-Agropyrion repentis, класу Artemisietea vulgaris. Угруповання асоціації Rubo сaesii-Calamagrostietum еpigeji сформовані Achillea millefolium, Calamagrostis epigejos, Convolvulus arvensis, Elymus repens, Poa angustifolia, Silene latifolia. У складі другої асоціації Elymo repentis-Rubetum caesii переважають чагарники Rubus caesius, R. polonicus, а також трав’яні рослини Artemisia vulgaris, Elymus repens, Galium aparine, Humulus lupulus, Lamium album, Urtica dioica. Порівняльний аналіз видового складу обох асоціацій показав, що досліджені угруповання утворюють окремі блоки діагностичних видів, мають деякі екологічні відмінності від союзу Convolvulo arvensis-Agropyrion repentis та разом з тим формують щільний комплекс видів класу Artemisietea vulgaris. За синфітоіндикаційним аналізом угруповання досліджених асоціацій займають мезофітні ділянки на слабкокислих ґрунтах, збагачених солями, відносно бідних на нітроген, з незначним вмістом карбонатів у ґрунті. Встановлено провідні екологічні фактори формування угруповань асоціацій: омброрежим, вологість, аерованості та вміст нітрогену у ґрунті, освітленість та змінність зволоження. Асоціації Rubo сaesii-Calamagrostietum еpigeji та Elymo repentis-Rubetum caesii мають ширший діапазон значень екологічних чинників, ніж угруповання союзу Convolvulo arvensis-Agropyrion repentis. Це обумовлено екотонним положенням синтаксонів, що сприяє формуванню строкатого трав’яного покриву за рахунок значної кількості випадкових видів (рудеральних, лучних та узлісних) і відображається на діапазоні значень екологічних показників.
The Role of Technology Adoption in Scaling Startupreneur Business Models in the Digital Economy
Authors: Delhi Ariana , Sijabat Apriani
Published: November 2024

Technology adoption plays a vital role in the digital business landscape, enabling startupreneurs to scale their businesses efficiently. In the era of the digital economy, adopting the right technologies can drive growth and enhance competitiveness. This study aims to understand how technology adoption contributes to the scaling of startupreneur business models. Using a mixed-methods approach, data was collected through quantitative surveys and in-depth interviews with 200 startupreneurs. The results indicate that cloud computing, e-commerce platforms, and mobile apps are the most impactful technologies, with cloud computing driving 30% business growth and 20% cost reduction. These findings highlight the importance of strategic technology adoption for startupreneurs seeking to expand their operations. The study offers practical insights into how startupreneurs can leverage digital tools for sustainable growth, and future research should explore the long-term impacts of emerging technologies like AI and blockchain.
Creating Competitive Advantage through Digital Innovation: Insights from Startupreneurs in E-Commerce
Authors: Nicola Gabriela , Setiawan Rony
Published: November 2024

Digital innovation has become a crucial factor in creating competitive advantage for startups in the e-commerce industry. In the fast-paced digital economy, startupreneurs must leverage technological advancements to differentiate themselves and ensure sustainable growth. This research aims to explore how digital innovation is utilized by startupreneurs in e-commerce to gain a competitive edge, focusing on the strategies that enhance market presence and customer loyalty. A mixed-method approach was adopted, combining surveys and in-depth interviews with e-commerce startupreneurs, along with a comprehensive literature review to provide a theoretical foundation. The findings indicate that startups implementing digital innovations such as automation, data analytics, and personalized customer experiences see significant improvements in customer satisfaction and operational efficiency. These innovations play a pivotal role in helping e-commerce startups maintain competitiveness in a saturated market. In conclusion, this study highlights the practical importance of adopting digital innovation for e-commerce startups and contributes to the theoretical understanding of how digital tools can drive entrepreneurial success in modern markets
Improving hospital-based opioid substitution therapy (iHOST): protocol for a mixed-methods evaluation
Authors: Lewer Dan , Brown Michael , Burns Adam , Eastwood Niamh , Gittins Rosalind , Holland Adam , Hope Vivian , Ko Aubrey , Lewthwaite Penny , Morris Ann-Marie , Noctor Adrian , Preston Andrew , Scott Jenny , Smith Erica , Sweeney Sedona , Tilouche Nerissa , Wickremsinhe Marisha , Harris Magdalena
Published: November 2024

Background Opioid substitution therapy (also known as ‘opioid agonist therapy’ or ‘medication treatment of opioid use disorder’) is associated with improved health and social outcomes for people who use heroin and other illicit opioids. It is typically managed in the community and is not always continued when people are admitted to hospital. This causes opioid withdrawal, patient-directed discharge, and increased costs. We are establishing a project called iHOST (improving hospital opioid substitution therapy) to address these problems. This is an applied health research project in which we will develop and evaluate an intervention that aims to improve opioid substitution therapy in three acute hospitals in England. The intervention was developed in collaboration with stakeholders including people who use opioids, hospital staff, and other professionals who work with this group. It includes five components: (1) a card that patients can use to help hospital clinicians confirm their opioid substitution therapy, (2) a helpline for patients and staff, (3) an online training module for staff, (4) a clinical guideline for managing opioid withdrawal in hospital, and (5) ‘champion’ roles at each hospital. Methods We will do a mixed-methods study including a quasi-experimental quantitative study and a qualitative process evaluation. The primary outcomes for the quantitative study are patient-directed discharge and emergency readmission within 28 days. We will do a difference-in-difference analysis comparing changes in these outcomes for patients at iHOST sites with changes for patients at control hospitals. The process evaluation will use in-depth interviews, focus groups, and site observations with people who use opioids and staff. We will assess acceptability of the intervention, barriers and facilitators to implementation, and contextual factors impacting outcomes. Impact We anticipate that iHOST will improve care for hospital patients who use illicit opioids and/or are receiving community-based opioid substitution therapy. Depending on the results, we will promote the intervention at hospitals across the UK. Dissemination, including through publication, will inform hospital-based services for people who use drugs both in the UK and other countries.
Effectiveness of Public Health Education on the Uptake of Iron-And Folic Acid Supplements Among Pregnant Women: Findings from a Stepped Wedge Cluster Randomized Trial
Authors:   Department of Family Medicine, Community Health and Epidemiology, Kenyatta University, Njiru Haron , Njogu Eunice ,   Department of Food, Nutrition and Dietetics, Kenyatta University, Gitahi Mary W. ,   Department of Family Medicine, Community Health and Epidemiology, Kenyatta University
Published: November 2024

Objective: To determine the effectiveness of public health education on the uptake of iron and folic acid supplements (IFAS) among pregnant women. Design: A stepped wedge cluster randomized trial. Setting: 12 antenatal care clinics (ANC) in Embu County - Kenya. The clinics are outpatient departments in health facilities dedicated to providing care for pregnant women. Participants: Pregnant women receiving antenatal care services in the study sites. Intervention: After a baseline observational phase, a multifaceted intervention bundle was implemented. The intervention included a 60-minute IFAS information session for health workers at the start of intervention. Health workers then provided daily IFAS literacy sessions to all the pregnant women and issued them with IFAS related information materials (a pill reminder card, and a personalized calendar). The study team conducted biweekly facility audits for quality assurance. The total duration of the study was 8 months, starting June 2022. Primary outcome: The primary outcome was the proportion of pregnant women taking IFAS daily in the intervention phase compared with control phase. This was measured through IFAS residual pill count during every ANC visit. Results: A total of 4,749 ANC visits were monitored for 2,132 women receiving antenatal care in the 12 clinics. Participant characteristics were similar across control and intervention phases. The uptake of IFAS significantly improved from 44.8% (95% CI 34.7 to 55.0) in control phase to 83.3% (95% CI 75.9 to 90.9) during the intervention. This translates to a 38.5 (95% CI 26.0 to 51.1) percentage points improvement. The number needed to treat (NNT) for this intervention was 3 patients (95% CI 2 to 4). Conclusion: IFAS uptake significantly improved following the intervention. The findings support public health education as an effective strategy for improving the uptake of IFAS in ANC settings.
LINGUISTIC ILLUSTRATIONS AS A SECONDARY SIGN (MICRO) SYSTEM
Authors:   O. O. Potebnia Institiute of Linguistics of the National Academy of Sciences of Ukraine, YERMOLENKO Serhii
Published: November 2024

The article focuses on the study of illustrations found in linguistic and language teaching literature from a perspective of their operating as a secondary semiotic system. Such systems can comprise a limited inventory of items and belong to a specific author’s discourse, where their field of reference is determined by the producent’s associations of individual and subjective nature, and therefore generally hidden from the average recipient. Also, they may be related, as their plan de signification, to social communicativefunctional discursive varieties (as those of state politics, ideology, or literary criticism). In both cases, the emergence of such secondary systems results from the conscious intent of the producent.
THE USE OF PERSUASIVE LANGUAGE TECHNIQUES IN TOP-END YOUTUBE VIDEOS ADVERTISING UKRAINIAN WINES
Authors:   National University of Kyiv-Mohyla Academy, POLSHCHAK Aneliia
Published: November 2024

In the article, Anelia Polishchak presents the results of a study aimed at evaluating the effectiveness of advertising Ukrainian wines on the YouTube platform by analyzing the most popular videos featuring this advertising. The study focuses on the use of linguistic tools and persuasive language techniques formulated by Brett Lamb. This approach allows for the identification of modern effective strategies in the advertising of Ukrainian wines. The study’s results show that the persuasive language techniques developed by Lamb are widely used in Ukrainian wine advertising. Furthermore, the research revealed the use of other techniques, such as positive forms in syntactic constructions and vocabulary, verbal hints, and more. These findings provide valuable insights into the development of linguistic strategies in advertising, demonstrating their adaptation to modern market demands.
Peran Orang Tua terhadap Penggunaan Gadget pada Anak Usia Dini Generasi Alpha
Authors: Mita Mita Lestari , Widjayatri RR. Deni
Published: November 2024

The alpha generation is children born between 2011-2025. Alpha generation children are very familiar with digital technology as if their lives cannot be separated from the internet or gadgets. Therefore, with the development of increasingly sophisticated and increasingly rapid technology, early childhood requires good care, supervision, and assistance from their parents while using gadgets. The purpose of this study was to find out how parents' role in using gadgets in the early childhood alpha generation. This research uses a literature study method from scientific articles, journals, books, and others previously conducted to answer this research. This study showed that parents are very important in children using their gadgets. For example, parents must accompany children when playing with their gadgets, maintain good communication withchildren, manage the time they use gadgets for children every day, and parents can use parental control applications to monitor children when using the internet. The alpha generation is children born between 2011-2025. Alpha generation children are very familiar with digital technology as if their lives cannot be separated from the internet or gadgets. Therefore, with the development of increasingly sophisticated and increasingly rapid technology, early childhood requires good care, supervision, and assistance from their parents while using gadgets. The purpose of this study was to find out how parents' role in using gadgets in the early childhood alpha generation. This research uses a literature study method from scientific articles, journals, books, and others previously conducted to answer this research. This study showed that parents are very important in children using their gadgets. For example, parents must accompany children when playing with their gadgets, maintain good communication with children, manage the time they use gadgets for children every day, and parents can use parental control applications to monitor children when using theinternet.
Pengembangan Kemampuan Motorik Kasar Berbasis Permainan Tradisional Lompat Tali pada Usia 4-5 tahun
Authors: Fitria Fadilatul , Amidanal Chikmah
Published: November 2024

Gross motor refers to the ability of large movements or motor skills that involve the use of large muscles in the body to perform physical activities. One way to develop gross motor skills is through traditional games. Traditional games refer to games that have existed and are played by the community from generation to generation. These games reflect the cultural heritage of each region. One of the heritage games in Java is Jump rope. This research aims to help children's gross motor development based on traditional jump rope games. At the age of 4-5 years, children make significant progress in their gross motor development. It is important to note that each child has a unique development and is different from one another, hence the need for a response from the environment to help optimize children's growth and development. The research method used in this study is classroom action research with 20 children. From the results of the research that has been carried out, gross motor development based on traditional jump rope games is proven to optimize the motor development of children aged 4-5 years, it can be seen by an increase in the percentage which initially only 7% increased to 25% in cycle 1, and 80% in cycle 2.
Strategi Profesionalisme Guru PAUD Abad 21 dalam Menstimulasi Kemampuan Membaca Anak Usia Dini
Authors: David Triatna  , Khamim Zarkasih Putro
Published: November 2024

21st-century ECE teachers face challenges in developing effective strategies to stimulate early reading abilities in children. This study aims to explore the strategy of 21st-century early childhood education (ECE) teachers' professionalism in stimulating early reading skills in young children focusing on the effectiveness of these strategies in enhancing children's interest and reading abilities. The study employs a descriptive qualitative research method, with two teachers from groups B1 and B2 of TK Piri Nitikan as the subjects. The findings highlight that the professionalism of 21st-century ECE teachers, particularly in using conventional picture storybooks and digital flipbooks, positively contributes to enhancing early reading skills. Conventional picture storybooks aid in developing fine motor skills and basic language abilities in children, while digital flipbooks offer a more interactive and engaging learning experience. Combining conventional and digital approaches in 21st-century ECE professionalism provides a strong foundation for improving early childhood reading abilities.
Microplastic and human health with focus on pediatric well-being: a comprehensive review and call for future studies
Authors: Chia Rogers Wainkwa , Atem Ntegang Venant , Lee Jin-Yong , Cha Jihye
Published: November 2024

Although humans are highly dependent on plastics from infancy to adolescence, these materials can degrade into ubiquitous microplastics (MPs) that affect individuals at every stage of life. However, information on the sources, mechanisms, detection techniques, and detrimental effects of MPs on children’s health from infancy to adolescence is limited. Hence, here we identified and reviewed original research papers published in 2017–2023 across 11 database categories in PubMed, Google Scholar, Scopus, and Web of Science to improve our understanding of MPs with a focus on pediatric well-being. These studies found that milk and infant formulas are common sources of MP exposure in infants. Infant formula is the dominant source of MPs in babies, while plastic toys are a common source of MPs in toddlers. Adolescents are frequently exposed to MPs through the consumption of food contaminated with MPs and the use of plastics in food packaging. Water and air are sources of MP exposure in children from infancy through adolescence. This study thoroughly summarized how MP exposure in children of all ages causes cell damage and leads to adverse health effects such as cancer. With appropriate authorization from the relevant authorities, small amounts of human biological samples (10 g of feces) were collected from volunteers to assess the amounts of MPs in children with the aim of promoting pediatric well-being. The samples were then treated with Fenton's reagent, stored in glass jars, and filtered through nonplastic filters. Finally, MPs in children were quantified using stereomicroscopy and characterized using micro-Fourier transform infrared spectroscopy.
Polysomnographic features of children with obesity: body mass index predict severe obstructive sleep apnea in obese children?
Authors: Sukharom Rungrat , Tovichien Prakarn , Udomittipong Kanokporn , Tiamduangtawan Pinyapach , Chotinaiwattarakul Wattanachai
Published: November 2024

Background: Few studies have explored the polysomnographic features of children with obesity.Purpose: This study aimed to explore the demographic and polysomnographic features of obese children and determine whether body mass index (BMI) could predict severe obstructive sleep apnea (OSA).Methods: This cross-sectional study recruited obese children who underwent diagnostic polysomnography between January 2019 and March 2022. We explored demographic and anthropometric measures as well as polysomnographic abnormalities among them. We used receiver operating characteristic curves and logistic regression analyses to determine the optimal cutoff values of anthropometric variables for predicting severe OSA.Results: A total of 132 children with obesity (76.5% male; mean age, 12.5±3.2 years) were included. Severe OSA was identified in 64 children (48.5%). Desaturation was observed in 59.8%, while 23.5% had hyperarousal, 20.5% had sleep-related hypoventilation, 60.6% had positional OSA, 40.2% had rapid eye movement-related OSA, and 5.0% had obesity hypoventilation syndrome. Among them, BMI (odds ratio [OR], 1.11; 95% confidence interval [CI], 1.05–1.17; P<0.001), neck circumference (OR, 1.15; 95% CI, 1.07–1.25; P<0.001), and waist circumference (OR, 1.04; 95% CI, 1.02– 1.07; P=0.001) were significantly associated with severe OSA. These findings suggest a cutoff BMI for predicting severe OSA of greater than 29.2 kg/m2 with 81.3% sensitivity and 48.5% specificity.Conclusion: Severe OSA is common in children with obesity; thus, we recommend screening children with obesity and a BMI greater than 29.2 kg/m2 for severe OSA.
Sentiment Analysis of Hotel Reviews in Anyer Beach Tourism Area: A Lexicon-Based Text Mining Approach
Authors: Fachrur Aditya Rahadian
Published: November 2024

This study aims to analyze tourist sentiment towards hotels in the Anyer beach tourism area through online reviews. Sentiments and emotions expressed in these reviews were analyzed using a lexicon-based approach from the National Research Council (NRC) lexicon, which includes emotion categories such as anger, fear, sadness, joy, and disgust. Hotel review data were collected from TripAdvisor, and the analysis involved text preprocessing steps such as cleaning, case folding, stemming, and stopword removal. The sentiment analysis results reveal that most tourists provided positive reviews, with only 14.06% of the reviews displaying negative sentiment. Word cloud visualization identified the words "bad" and "dirty" as frequently appearing in negative reviews, likely pointing to cleanliness and service quality issues as the primary reasons for dissatisfaction. Emotional analysis showed dominant feelings of sadness, anger, disgust, and fear, likely triggered by unmet expectations regarding cleanliness and comfort during their stay. Based on these findings, it is recommended that hotel management in the Anyer beach tourism area address these concerns by implementing regular cleaning routines and staff training to enhance hotel service quality.
Surface-modified CMOS biosensors
Authors: Dehghandehnavi Fahimeh , Sajal Md. Sakibur , Dandin Marc
Published: November 2024

Biosensors translate biological events into electronic signals that quantify biological processes. They are increasingly used inin vitrodiagnostics applications that leverage their ability to process small sample volumes. One recent trend has been to integrate biosensors with complementary metal-oxide-semiconductor (CMOS) chips to provide enhanced miniaturization, parallel sensing, and low power consumption at a low cost. CMOS-enabled biosensors are used in monitoring DNA hybridization, enzymatic reactions, and cell proliferation, to name a few applications. This paper explores the materials and processes used in emerging CMOS biosensors. We discuss subtractive and additive processes for creating electrodes for electrochemical sensing applications. We discuss functionalization techniques for creating bioelectronic interfaces that allow molecular events to be transduced into the electrical domain using a plurality of modalities that are readily provided by CMOS chips. Example modalities featured are optical sensing, electrochemical detection, electrical detection, magnetic sensing, and mechanical sensing.
Refrigerated amniotic membrane maintains its therapeutic qualities for 48 hours
Authors: Stelling-Férez J. , Puente-Cuadrado J. M. , Álvarez-Yepes V. , Alcaraz S. , Tristante E. , Hernández-Mármol I. , Mompeán-Egea I. , García-Hernández A. M. , Nicolás F. J.
Published: November 2024

During wound healing, the migration of keratinocytes is critical for wound closure. The application of amniotic membrane (AM) on wounds with challenging contexts (e.g., chronification and diabetic foot ulcer) has proven very successful. However, the use of AM for clinical practice has several restraints when applied to patients; the most important restriction is preserving AM’s therapeutic properties between its thawing and application onto the patient’s wound. Moreover, AM collection and processing requires a cleanroom, together with specialized staff and equipment, and facilities that are not usually available in many hospitals and healthcare units. In this publication, we kept previously cryopreserved AM at different temperatures (37°C, 20°C, and 4°C) in different media (DMEM high glucose and saline solution with or without human albumin) and for long incubation time periods after thawing (24 h and 48 h). HaCaT keratinocytes and TGF-β1-chronified HaCaT keratinocytes were used to measure several parameters related to wound healing: migration, cell cycle arrest rescue, and the expression of key genes and migration-related proteins. Our findings indicate that AM kept in physiological saline solution at 4°C for 24 h or 48 h performed excellently in promoting HaCaT cell migration compared to AM that had been immediately thawed (0 h). Indeed, key proteins, extracellular signal-regulated kinase (ERK) and c-Jun, were induced by AM at 4°C in saline solution. Similarly, cell proliferation and different genes related to survival, inflammation, and senescence had, in all cases, the same response as to standard AM. These data suggest that the handling method in saline solution at 4°C does not interfere with AM’s therapeutic properties.
Development of methodology for calculating flooded area and flood volume in small urban areas based on unmanned aerial vehicle images
Authors: Woo Hyun-Jung , Seo Dong-Min , Kim Min-Seok , Lee Hye-Kyoung
Published: November 2024

Climate change has intensified flooding and increased localized torrential rainfalls, leading to disasters such as landslides, infrastructure collapse, and urban floods. The extent and accuracy of flood damage information significantly impact recovery processes. While previous studies primarily utilized satellite and aerial imagery for broad flood assessments, they often lacked the precision needed for accurate damage analysis. This study addresses the gap between rapid assessment needs and precise damage quantification in flood inundation analysis. This research introduces a novel image-based investigation approach to enhance the speed and accuracy of flood inundation assessment. By leveraging unmanned aerial vehicles (UAVs) and image-based spatial data technology, aerial images of flooded areas are rapidly captured to construct three-dimensional disaster site terrain information. The proposed methodology employs advanced techniques in aerial photography, image processing, and geographic analysis to quantitatively analyze flood inundation scale using only aerial images and geographic information systems (GIS). The research yielded a calculated flood inundation area of 3,847.36 m2 and a flood volume of 13,895.13 m3. This methodology complements existing flood inundation assessment techniques and has the potential to significantly improve disaster management efforts by providing rapid, accurate, and actionable data for decision-makers.
Evolution of g-type lysozymes in metazoa: insights into immunity and digestive adaptations
Authors: Mukherjee Krishanu , Moroz Leonid L.
Published: November 2024

Exploring the evolutionary dynamics of lysozymes is critical for advancing our knowledge of adaptations in immune and digestive systems. Here, we characterize the distribution of a unique class of lysozymes known as g-type, which hydrolyze key components of bacterial cell walls. Notably, ctenophores, and choanoflagellates (the sister group of Metazoa), lack g-type lysozymes. We reveal a mosaic distribution of these genes, particularly within lophotrochozoans/spiralians, suggesting the horizontal gene transfer events from predatory myxobacteria played a role in their acquisition, enabling specialized dietary and defensive adaptations. We further identify two major groups of g-type lysozymes based on their widespread distribution in gastropods. Despite their sequence diversity, these lysozymes maintain conserved structural integrity that is crucial for enzymatic activity, underscoring independent evolutionary pathways where g-type lysozymes have developed functionalities typically associated with different lysozyme types in other species. Specifically, using Aplysia californica as a reference species, we identified three distinct g-type lysozyme genes: two are expressed in organs linked to both feeding and defense, and the third exhibits broader distribution, likely associated with immune functions. These findings advance our understanding of the evolutionary dynamics shaping the recruitment and mosaic functional diversification of these enzymes across metazoans, offering new insights into ecological physiology and physiological evolution as emerging fields.
Experimental and advanced equilibrium studies on the enhanced adsorption of phosphate, cadmium, and safranin dye pollutants using methoxy exfoliated glauconite
Authors: Abukhadra Mostafa R. , Fadl Allah Aya , Shaban Mohamed , Alenazi Noof A. , Alqhtani Haifa A. , Bin-Jumah May , Allam Ahmed A. , Bellucci Stefano
Published: November 2024

Natural glauconite, as a mixed-layered clay mineral, was subjected to exfoliation processes, producing silicate monolayers or individual sheets that were further modified with methanol into methoxy exfoliated glauconite (Mth/EXG). The structure was assessed as an enhanced adsorbent for three types of common water contaminants, including phosphate (PO43-), safranin-O dye (SFR), and cadmium metal ions (Cd2+). The Mth/EXG structure achieved promising adsorption capacities at the saturation points equal to 269.9 mg/g for PO43-, 312 mg/g for SFR, and 234.5 mg/g for Cd2+ which are significantly better than the reported values for several studied adsorbents of higher costs and complex production procedures. The adsorption processes and the predicted regulated mechanisms in terms of the adsorbate/adsorbent interface were illustrated based on the steric and energetic findings that correspond to the applied monolayer equilibrium model of one energy site. The structure displays active site densities of 82.5 mg/g (PO43-), 136.3 mg/g (SFR), and 83.4 mg/g (Cd2+), which illustrate the high uptake performance of SFR. Also, the steric parameters reflected the suitability of each existing site to be filled with 4 ions of PO43-, SFR, and Cd2+. The adsorption energy (less than 40 kJ/mol) in conjunction with free adsorption energy from D-R model (8–16 kJ/mol) and steric parameters validate the dominant impact of the multi-ionic physical mechanisms (hydrogen bonding and van der Waals forces), in addition to the assistant impact of some weak chemical processes that might be assigned to the formed inner-sphere complex. Also, these reactions all occurred spontaneously with exothermic behaviors according to the thermodynamic functions. Additionally, the structure exhibit significant affinity for the studied pollutants even in the existing of completive chemical including anions, cations and organic molecules.