bluuebunny/crossref_metadata_2025 huggingface dataset:
In Vitro Tracing of Cytotoxic Compounds in Jarak Cina Stem Bark (Jatropha Multifida Linn.)
Authors: Werdyani Sista , Fitria Annisa , Rakhmawati Sari
Published: January 2020

Cancer remains one of the diseases with increasing number of sufferers, but research on compounds that act as anti-cancer is also ongoing. Terpenoids have been known as a compound that can inhibit the proliferation of cancer cells. One of the medical plants that produce terpenoids is Jarak cina (Jatropha multifida Linn.). Therefore, the possibility of Jarak cina (Jatropha multifida Linn.) to have an cytotoxic activity on cancer cell proliferation is reasonably high. This study was conducted to determine the cytotoxic activity of Jarak cina (Jatropha multifida Linn.) bark extracts against cancer cell MCF-7. Jarak cina bark was extracted using the multilevel soxhlet extraction method with n-hexane, ethyl acetate, and ethanol as the solvents. All the three extracts were then tested against MCF-7 cancer cells using MTT (3-(4,5-dimethylthiazol-2-yl) - 2,5-diphenyltetrazolium bromide) method. Data analysis was performed for IC50 (ppm) parameter. The results showed that the IC50 of n-hexane extract was 313.21 ppm, while the ethyl acetate extract reached 258.38 ppm of IC50, and the IC50 of ethanol extract was 418.51 ppm. The highest potential of cytotoxicity was found in the ethyl acetate extract, so further testing would be required to optimize the proliferation inhibitory activity.
Characterization of Newcastle Disease Virus in Southeast Asia and East Asia: Fusion Protein Gene
Authors: Ansori Arif Nur Muhammad , Kharisma Viol Dhea
Published: January 2020

The aim of this study was to generate the bioinformatics analysis of the circulating NDVs in Southeast Asia, East Asia, and the vaccine virus strains through a database of isolates stored in GenBank® (National Center for Biotechnology Information, USA). The used isolates were AJ629062.1 (La Sota), AF309418.1 (B1), EF201805.1 (Mukteswar), KT445901.1 (Komarov), JX524203.1 (V4), AY935499.2 (I-2), KC987036.1 (F), KF767104.1 (Indonesia), KF767105.1 (Indonesia), KF767106.1 (Indonesia), HQ697255.1 (Indonesia), HQ697256.1 (Indonesia), HQ697261.1 (Indonesia), JX012096.2 (Malaysia), GU332646.1 (Vietnam), AF358786.1 (Taiwan), AF358788.1 (China), KT380032.1 (Republic of Korea), and KC503416.1 (Japan). As the results, this study have revealed the data of homology, pathotype, genetic distance, B cell epitope prediction, and molecular phylogenetic analysis of circulating NDVs in Southeast Asia and East Asia and vaccine virus strains. Thus, the results of this study can be used as a reference for vaccine design studies in the applications of poultry vaccine industryReceived: 28 August 2019; Accepted: 31 December 2019; Published: 11 January 2020.
EFFECT OF COOKING ON IRON AVAILIBILITY IN FORTIFIED HOMEMADE TEMPEH
Authors: Mahardika Micha , Amin Fauzan , Ganda Risdiyono Arda
Published: January 2020

Iron deficiency anemia is a type of anemia caused by iron deficiency, decreasing in the number of healthy red blood cells. The purpose of this study was to make fortified iron-EDTA and find out changes in iron availability after cooking (frying and boiling). The biological availability test for iron was carried out in vitro by simulating human digestion using enzyme pepsin and pancreatin-bile solution. The iron variants added were 0, 10, 20, 30, 40, and 50 mg of EDTA iron on 30 grams of raw soybeans to be homemade tempeh. Test results with SSA showed that the highest Fe content of 12.5356 mg was obtained by adding 50 mg of EDTA iron to raw tempeh. But after cooking, there is a decrease in fried tempeh and boiled tempeh. Where the results obtained from the addition of 50 mg of iron-EDTA are 7.7406 mg for fried tempeh, and 8.3969 mg for boiled tempeh. The results of the addition of iron fortune EDTA 50 mg for raw tempeh and boiled tempeh reached the right range for the value of daily Fe intake to reduce iron anemia in the amount of 8-15 mg / day according to Recommendation Dietary Allowance (RDA). As for fried tempeh with the addition of 50 mg of EDTA iron fortification, it still has not reached the recommended levels.
Neural Network Model for Mathematic Scores Prediction: Case Study in SMK Negeri Pakis Aji, Jepara, Indonesia
Authors: Sucipto Adi , Minardi Joko
Published: January 2020

Aim of this research is to apply Neural Network Algorithm to predict score of mathematic in the national exam. During the time, the teacher only provided national exam materials and additional tryout tests without knowing how to predict the exam scores in mathematics subject. Data mining neural network algorithm obtained \Root Mean Square Error (RMSE) values which were used as basic improvement and clustering class By conducting research using data mining neural network algorithm, it proved that this model can be used to predict scores of Mathematics subject at SMK Negeri 1 Pakis Aji.. The result of this research by using data mining neural network algorithm found RMSE 0138 +/- 0.092. The lower the RMSE values the more accurate the neural network to predict mathematics scores of SMK Negeri 1 Pakis Aji.Received: 18 Agustus 2019; Accepted: 5 Januari 2020; Published: 14 January 2020
Dynamic Changes of pStat3 are Involved in Meiotic Spindle Assembly in Mouse Oocytes
Authors: Haraguchi Seiki , Ikeda Mitsumi , Akagi Satoshi , Hirao Yuji
Published: January 2020

The signal transducer and activator of transcription 3 (Stat3) is activated in response to the phosphorylation of Y705 (pStat3) and has the dual function of signal transduction and activation of transcription. Our previous study suggested that pStat3 is functional during oocyte maturation when transcription is silenced. Therefore, we speculated that pStat3 may have another function. Immunocytochemical analysis revealed that pStat3 emerges at the microtubule asters and spindle and then localizes at the spindle poles concomitant with a Pericentrin during mouse oocyte maturation. When we examined conditionally knocked out Stat3−/− oocytes, we detected Stat3 and pStat3 proteins. The localization of the pStat3 was the same as that of Stat3+/+ oocytes, and the oocyte maturation proceeded normally, suggesting that pStat3 was still functioning. The oocytes were treated either with the Stat3 specific inhibitors, Stattic and BP-1-102, or anti-pStat3 antibody injection. This caused significant abnormal spindle assembly and chromosome mis-location in a dose-dependent manner, in which the pStat3 was either negative or localized improperly. Moreover, development of pre-implantation stage embryos derived from inhibitor-treated oocytes was also hampered significantly after in vitro fertilization. These findings indicate a novel function of pStat3 involved in spindle assembly.
Ranking Port State Control Detention Remarks: Professional Judgement and Spatial Overview
Authors: Akyrek Efe , Bolat Pelin
Published: January 2020

Merchant marine fleet is under inspections by several parties to ensure maritime regulation compliance. One of the major effects on implementation of regulations by International Maritime Organization (IMO) is indeed Port State Control. This article aims to analyze Paris Memoranda of Understanding (MOU) all detention remarks from 2013 to 2019 for EU15 countries (except Luxemburg and Austria) through an approach based on Analytical Hierarchy Process and demonstrate the results on Geographic Information System (GIS) to guide marine industry on detainable Port State Control remarks and country risk profile. While Analytical Hierarchy Process Approach has been used to indicate the ranking of basic maritime regulations from the perspective of the port state control , GIS help us to demonstrate the regional dispersion amongst EU15. The data of the detained vessel taken from the public website of Paris MOU and each report considered as a professional judgement that causes detention. It has been shown that almost all countries top priorities for regulation are Safety of Life at Sea (SOLAS) and Fire Safety Systems (FSS). Consequently, the results of the study can assist Port State Officers, ship crew, ship owners and managers presenting the facts of their inspection and able to improve themselves. The spatial analysis also expected to guide ship owners and managers to focus their vessel’s deficiencies to prevent sub-standardization.
Energy-Efficient Method for Wireless Sensor Networks Low-Power Radio Operation in Internet of Things
Authors: Amiri Nasab Mehdi , Shamshirband Shahaboddin , Chronopoulos Anthony Theodore , Mosavi Amir , Nabipur Narjes
Published: January 2020

The radio operation in wireless sensor networks (WSN) in the Internet of Things (IoT) applications are the most common source for power consumption. However, recognizing and controlling the factors affecting radio operation can be valuable for managing the node power consumption. ContikiMAC is a low-power Radio Duty-Cycle protocol in Contiki OS used in WakeUp mode, which is a clear channel assessment (CCA) to check radio status periodically. The time spent to check the radio is of utmost importance for monitoring power consumption. It can lead to false WakeUp or idle listening in Radio Duty-Cycles and ContikiMAC. This paper presents a detailed analysis of radio WakeUp time factors of ContikiMAC. Then, we propose lightweight CCA (LW-CCA) as an extension to ContikiMAC to reduce the percentage of Radio Duty-Cycles in false WakeUps and idle listenings by using dynamic received signal strength indicators (RSSI) status check time. The simulation results in the Cooja simulator show that LW-CCA reduces about 8% energy consumption in nodes while maintaining up to 99% of the packet delivery rate (PDR).
A Guide and Toolbox to Replicability and Open Science in Entomology
Authors: Wittman Jacob , Aukema Brian
Published: January 2020

The ability to replicate scientific experiments is a cornerstone of the scientific method. Sharing ideas, workflows, data, and protocols facilitates testing the generalizability of results, increases the speed that science progresses, and enhances quality control of published work. Fields of science such as medicine, the social sciences, and the physical sciences have embraced practices designed to increase replicability. Granting agencies, for example, may require data management plans and journals may require data and code availability statements along with the deposition of data and code in publicly available repositories. While many tools commonly used in replicable workflows such as distributed version control systems (e.g. “git”) or scripted programming languages for data cleaning and analysis may have a steep learning curve, their adoption can increase individual efficiency and facilitate collaborations both within entomology and across disciplines. The open science movement is developing within the discipline of entomology, but practitioners of these concepts or those desiring to work more collaboratively across disciplines may be unsure where or how to embrace these initiatives. This article is meant to introduce some of the tools entomologists can incorporate into their workflows to increase the replicability and openness of their work. We describe these tools and others, recommend additional resources for learning more about these tools, and discuss the benefits to both individuals and the scientific community and potential drawbacks associated with implementing a replicable workflow.
Comparative Proteomic Analysis of Wild-Type Physcomitrella patens and an OPDA-Deficient Physcomitrella patens Mutant with Disrupted PpAOS1 and PpAOS2 Genes after Wounding
Authors: Luo Weifeng , Komatsu Setsuko , Abe Tatsuya , Matsuura Hideyuki , Talahashi Kosaku
Published: January 2020

Wounding is a serious environmental stress in plants. Oxylipins such as jasmonic acid play an important role in defense against wounding. Mechanisms to adapt to wounding have been investigated in vascular plants; however, those mechanisms in nonvascular plants remain elusive. To examine the response to wounding in Physcomitrella patens, a model moss, a proteomic analysis of wounded P. patens was conducted. Proteomic analysis showed that wounding increased the abundance of proteins related to protein synthesis, amino acid metabolism, protein folding, photosystem, glycolysis, and energy synthesis. 12-Oxo-phytodienoic acid (OPDA) was induced by wounding and inhibited growth. Therefore, OPDA is considered a signaling molecule in this plant. Proteomic analysis of a P. patens mutant in which the PpAOS1 and PpAOS2 genes, which are involved in OPDA biosynthesis, are disrupted showed accumulation of proteins involved in protein synthesis in response to wounding in a similar way to the wild-type plant. In contrast, the fold-changes of the proteins in the wild-type plant were significantly different from those in the aos mutant. This study suggests that PpAOS gene expression enhances photosynthesis and effective energy utilization in response to wounding in P. patens.
Role of Signal Transduction Pathways and Transcription Factors in Cartilage and Joint Diseases
Authors: Nishimura Riko , Hata Kenji , Takahata Yoshifumi , Murakami Tomohiko , Nakamura Eriko , Ohkawa Maki , Ruengsinpinya Lerdluck
Published: January 2020

Osteoarthritis and rheumatoid arthritis are common cartilage and joint diseases that globally affect more than 200 and 20 million people, respectively. Several transcription factors have been implicated in the onset and progression of osteoarthritis, including Runx2, C/EBPβ, HIF2α, Sox4, and Sox11. IL-1β also leads to osteoarthritis through NF-ĸB, IκBζ, and Zn2+-ZIP8-MTF1 axis. IL-1, IL-6, and TNFα play a major pathological role in rheumatoid arthritis through NF-ĸB and JAK/STAT pathways. Indeed, inhibitory reagents for IL-1, IL-6, and TNFα provide clinical benefits for rheumatoid arthritis patients. Several growth factors, such as BMP, FGF, PTHrP, and Indian hedgehog, play roles regulating chondrocyte proliferation and differentiation. Disruption and excess of these signaling cause genetic disorders in cartilage and skeletal tissues. FOP, an autosomal genetic disorder characterized by ectopic ossification, is induced by mutant ACVR1. mTOR inhibitors were found to prevent ectopic ossification by ACVR1 mutations. ACH and related diseases are autosomal genetic diseases, which manifest severe dwarfism. CNP is currently the most promising therapy for ACH. In these ways, investigation of cartilage and chondrocyte diseases at molecular and cellular levels sheds light on the development of effective therapies. Thus, identification of signaling pathways and transcription factors implicated in these diseases is important.
Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain
Authors: Chandler Peter G. , Buckle Ashley M.
Published: January 2020

As a non-antibody scaffold, monobodies based on the fibronectin type III (FN3) domain overcome antibody size and complexity while maintaining analogous binding loops. However, antibodies and their derivatives remain the gold standard for design of new therapeutics. In response, clinical therapeutic proteins based on the FN3 domain are beginning to use native fibronectin function as a point of differentiation. The small and simple structure of monomeric monobodies confers increased tissue distribution and reduced half-life, whilst the absence of disulphide bonds improves stability in cytosolic environments. Where multi-specificity is challenging with an antibody format that is prone to mis-pairing of chains, FN3 domains in the fibronectin assembly already interact with a large number of molecules. As such, multiple monobodies engineered for interaction with therapeutic targets are being combined in a similar beads-on-a-string assembly which improves both efficacy and pharmacokinetics. Furthermore, full length fibronectin is able to fold into multiple conformations as part of its natural function and a greater understanding of how mechanical forces allow for the transition between states will lead to advanced applications that truly differentiate the FN3 domain as a therapeutic scaffold.
Penerapan Teknologi Image Processing untuk Optimalisasi Petik Merah pada Kebun Kopi Rakyat.
Authors: Budianto Aris
Published: January 2020

Coffee has been cultivated as the secondary produce for decades in Girimarto, Wonogiri, however, the selective picking practice remain alient for local farmers. Selective picking is considered impractical due to time consumption and laborous work that farmers should carry out. The community service project designs and implements image recognition technology to help acquire    coffee-cheery ripeness condition. Adopting a geolocation, the appropriate routing strategies, would enable farmers to selectively pick the red cherries in a systematic sequence. The image processing technology was applied by adopting Raspberry Pi microcomputer, IP camera ReoLink RLC411WS, and OpenCV programming language. The transition to selective picking and the subsequent post-harvest technology would likely produce high-quality green bean coffee. It is expected that the income of smallholder coffee farmers will gradually be increasing.
Penggunaan Aplikasi “Kosipin“ Untuk Meningkatkan Akuntabilitas Pada Koperasi Simpan Pinjam “Gemah Ripah” desa Busukan, Kelurahan Mojosongo, Surakarta
Authors: Chrisnawati Henny Ekana , Nurhasanah Farida , Pramesti Getut , Triyanto Triyanto , Setyawan Rubono
Published: January 2020

Tujuan kegiatan pengabdian ini adalah memberikan usulan alternative penggunaan aplikasi pemrograman guna untuk peningkatan manajemen dalam memenuhi akuntabilitas pada koperasi simpan pinjam “ Gemah Ripah” desa Busukan, Mojosongo, Surakarta, dimana koperasi simpan pinjam tersebut didirikan dan dikelola oleh swadaya masyarakat, dimanfaatkan dan diperuntukkan oleh warga sendiri.Dengan adanya aplikasi Kosipin yang dikembangkan oleh tim abdimas tersebut, maka diharapkan dapat membantu optimalisasi kerja pengurus sehingga mampu menjaga keberlangsungan koperasi masyarakat tersebut sendiri. Pengembangan aplikasi tersebut dengan menggunakan Microsoft Acces, suatu program aplikasi keluaran Microsoft yang berguna untuk membuat, mengolah, dan mengelola database model relasional yang saling berhubungan sehingga menghasilkan informasi (report) semua input data tentang aktivitas keanggotaan dalam bentuk, peminjaman, riwayat peminjaman, setoran tabungan (simpanan) yang memudahkan pengurus untuk melakukan administrasi.
Metric Dimension of Generalized Möbius Ladder and its Application to WSN Localization
Authors: Idrees Muhammad , Ma Hongbin , Wu Mei , Nizami Abdul Rauf , Munir Mobeen , Ali Sajid ,   School of Automation, Beijing Institute of Technology No.5 South Zhongguancun Street, Haidian District, Beijing 100081, China,   Abdus Salam School of Mathematical Sciences, Government College University Lahore 68-B, New Muslim Town, Lahore, Punjab 54600, Pakistan,   Department of Computer Science, University of Education DG Khan Campus, Kangan Road, DG Khan, Punjab, Pakistan
Published: January 2020

Localization is one of the key techniques in wireless sensor network. While the global positioning system (GPS) is one of the most popular positioning technologies, the weakness of high cost and energy consuming makes it difficult to install in every node. In order to reduce the cost and energy consumption only a few nodes, called beacon nodes, are equipped with GPS modules. The remaining nodes obtain their locations through localization. In order to find the minimum positions of beacons, a resolving set with minimal cardinality has been obtained in the network which is called metric basis. Simultaneous local metric basis of the network is also given in which each pair of adjacent vertices of the network is distinguished by some element of simultaneous local metric basis which makes the network design more reasonable. In this paper a new network, the generalized Möbius ladderMm,n, has been introduced and its metric dimension and simultaneous local metric dimension of its two subfamilies have been calculated.
Observer-Based Piecewise Multi-Linear Controller Designs for Nonlinear Systems Using Feedback and Observer Linearizations
Authors: Taniguchi Tadanari , Sugeno Michio ,   Tokai University 4-1-1 Kitakaname, Hiratsuka, Kanagawa 259-1292, Japan,   Tokyo Institute of Technology 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8503, Japan
Published: January 2020

This paper proposes observer-based piecewise multi-linear controllers for nonlinear systems using feedback and observer linearizations. The piecewise model is a nonlinear approximation and fully parametric. Feedback linearizations are applied to stabilize the piecewise multi-linear control system. Furthermore, observer linearizations are more conservative in modeling errors compared with feedback linearizations. In this paper, we propose robust observer designs for piecewise multi-linear systems. Moreover, we design piecewise multi-linear controllers that combine the robust observer with various performance such as a regulator and tracking controller. These design methods realize a separation principle that allows an observer and a regulator to be designed separately. Examples are demonstrated through computer simulation to confirm the feasibility of our proposals.
A Hybrid Fuzzy System Dynamics Approach for Risk Analysis of AUV Operations
Authors: Loh Tzu Yang , Brito Mario P. , Bose Neil , Xu Jingjing , Nikolova Natalia , Tenekedjiev Kiril ,   Australian Maritime College, University of Tasmania 1 Maritime Way, Launceston, Tasmania 7250, Australia,   Southampton Business School, University of Southampton Building 2, 12 University Road, Highfield, Southampton SO17 1BJ, United Kingdom,   Memorial University of Newfoundland 230 Elizabeth Avenue, St. John’s, Newfoundland and Labrador A1C 5S7, Canada,   Faculty of Business, University of Plymouth Cookworthy Building, Drake Circus, Plymouth PL4 8AA, United Kingdom,   Nikola Vaptsarov Naval Academy 73 Vasil Drumev Street, Varna 9026, Bulgaria
Published: January 2020

The maturing of autonomous technology has fostered a rapid expansion in the use of Autonomous Underwater Vehicles (AUVs). To prevent the loss of AUVs during deployments, existing risk analysis approaches tend to focus on technicalities, historical data and experts’ opinion for probability quantification. However, data may not always be available and the complex interrelationships between risk factors are often neglected due to uncertainties. To overcome these shortfalls, a hybrid fuzzy system dynamics risk analysis (FuSDRA) is proposed. The approach utilises the strengths while overcoming limitations of both system dynamics and fuzzy set theory. Presented as a three-step iterative framework, the approach was applied on a case study to examine the impact of crew operating experience on the risk of AUV loss. Results showed not only that initial experience of the team affects the risk of loss, but any loss of experience in earlier stages of the AUV program have a lesser impact as compared to later stages. A series of risk control policies were recommended based on the results. The case study demonstrated how the FuSDRA approach can be applied to inform human resource and risk management strategies, or broader application within the AUV domain and other complex technological systems.
A Heuristic-Based Model for MMMs-Induced Fuzzy Co-Clustering with Dual Exclusive Partition
Authors: Honda Katsuhiro ,   Osaka Prefecture University 1-1 Gakuen-cho, Nakaku, Sakai, Osaka 599-8531, Japan, Hakui Yoshiki , Ubukata Seiki , Notsu Akira
Published: January 2020

MMMs-induced fuzzy co-clustering achieves dual partition of objects and items by estimating two different types of fuzzy memberships. Because memberships of objects and items are usually estimated under different constraints, the conventional models mainly targeted object clusters only, but item memberships were designed for representing intra-cluster typicalities of items, which are independently estimated in each cluster. In order to improve the interpretability of co-clusters, meaningful items should not belong to multiple clusters such that each co-cluster is characterized by different representative items. In previous studies, the item sharing penalty approach has been applied to the MMMs-induced model but the dual exclusive constraints approach has not yet. In this paper, a heuristic-based approach in FCM-type co-clustering is modified for adopting in MMMs-induced fuzzy co-clustering and its characteristics are demonstrated through several comparative experiments.
Spatial Deployment of Heterogeneous Sensors in Complex Environments
Authors: Jiao Lei , Peng Zhihong ,   School of Automation, Beijing Institute of Technology 5 South Zhongguancun Street, Haidian District, Beijing 100081, China,   Key Laboratory of Intelligence Control and Decision of Complex Systems 5 South Zhongguancun Street, Haidian District, Beijing 100081, China
Published: January 2020

Studies on the deployment of sensors mostly involve a 2D plane or 3D volume. However, the optimal sensor deployment in field environments is actually the resource distribution on 3D surfaces. Compared with the traditional deployment environments, field environments are more complicated, owing to some interferences on the detection capability of sensors and limitations on the maneuverability of platforms. In this paper, an optimal sensor deployment algorithm in 3D complex environments is discussed. First, considering the characteristics of field environments, the maneuverability matrix of heterogeneous platforms was introduced as a constraint. Then, a non-isomorphic environment value distribution map was constructed to mark the differences among mission areas. Furthermore, the sensor detection range model was improved to better deal with the occlusion issue. Finally, based on the multi-objective particle swarm optimization (MOPSO) algorithm, a sensor deployment strategy was deployed for complex environments. Experiments demonstrated that the proposed algorithm can better deal with the sensor deployment problem in field environments, while improving the detection accuracy of the objects in mission areas.
IDT and Color Transfer-Based Color Calibration for Images Taken by Different Cameras
Authors: Ueda Yoshiaki , Misawa Hideaki , Koga Takanori , Suetake Noriaki , Uchino Eiji ,   Graduate School of Science and Technology for Innovation, Yamaguchi University 1677-1 Yoshida, Yamaguchi, Yamaguchi 753-8512, Japan,   Department of Electrical Engineering, National Institute of Technology, Ube College 2-14-1 Tokiwadai, Ube, Yamaguchi 755-8555, Japan,   Department of Electrical Engineering, National Institute of Technology, Tokuyama College Gakuendai, Shunan, Yamaguchi 745-8585, Japan
Published: January 2020

Images of the same object taken by multiple different cameras should have the same color reproduction. However, the images sometimes show different color reproduction due to the individual differences of cameras or internal camera parameters automatically determined when the images are taken. Conventional color transfer methods can be used for unifying the color reproduction of images by transforming the color distribution of an image to that of a reference image. However, conventional methods do not always lead to a good color reproduction and sometimes result in the loss of color impression of original images. In the present paper, we propose a color calibration method for images of the same object taken by different cameras. Two color transfer methods are combined to realize color calibration without the loss of color impression of an original image. Resultant images obtained by the color transfer methods are appropriately mixed into an output image. In experiments, the proposed method is applied to a variety of images and the effectiveness of the proposed method is confirmed by subjective and objective evaluations.
Exploratory Causal Analysis of Open Data: Explanation Generation and Confounder Identification
Authors: Song Jing , Oyama Satoshi , Kurihara Masahito ,   Graduate School of Information Science and Technology, Hokkaido University Nishi 9, Kita 14, Kita-ku, Sapporo, Hokkaido 060-0814, Japan,   Global Institution for Collaborative Research and Education, Hokkaido University Nishi 5, Kita 8, Kita-ku, Sapporo, Hokkaido 060-0808, Japan,   RIKEN Center for Advanced Intelligence Project 15th floor, Nihonbashi 1-chome Mitsui Building, 1-4-1 Nihonbashi, Chuo, Tokyo 103-0027, Japan
Published: January 2020

Open data are becoming increasingly available in various domains, and many organizations rely on making decisions according to data. Such decision making requires care to distinguish between correlations and causal relationships. Among data analysis tasks, causal relationship analysis is especially complex because of unobserved confounders. For example, to correctly analyze the causal relationship between two variables, the possible confounding effect of a third variable should be considered. In the open-data environment, however, it is difficult to consider all possible confounders in advance. In this paper, we propose a framework for exploratory causal analysis of open data, in which possible confounding variables are collected and incrementally tested from a large volume of open data. To the extent of the authors’ knowledge, no framework has been proposed to incorporate data for possible confounders in causal analysis process. This paper shows an original way to expand causal structures and generate reasonable causal relationships. The proposed framework accounts for the effect of possible confounding in causal analysis by first using a crowdsourcing platform to collect explanations of the correlation between variables. Keywords are then extracted using natural language processing methods. The framework searches the related open data according to the extracted keywords. Finally, the collected explanations are tested using several automated causal analysis methods. We conducted experiments using open data from the World Bank and the Japanese government. The experimental results confirmed that the proposed framework enables causal analysis while considering the effects of possible confounders.
A Robot in a Human–Robot Group Learns Group Norms and Makes Decisions Through Indirect Mutual Interaction with Humans
Authors: Fuse Yotaro , Takenouchi Hiroshi , Tokumaru Masataka ,   Kansai University Graduate School 3-3-35 Yamate-cho, Suita-shi, Osaka 564-8680, Japan,   Fukuoka Institute of Technology 3-30-1 Wajiro-higashi, Higashi-ku, Fukuoka 811-0295, Japan,   Kansai University 3-3-35 Yamate-cho, Suita-shi, Osaka 564-8680, Japan
Published: January 2020

In this study, we investigate whether group norms occur in human–robot groups. At present, there are a number of studies that examine social robots’ ways of responding, gesturing, and displaying emotion. However, sociality implies that robots not only exhibit human-like behaviors, but also display the tendency to adapt to a group of individuals. For robots to exhibit sociality, they must adapt to group norms without being told by the group members how to behave. Group norms refer to the unwritten, unspoken, and informal rules that are present in a group of individuals. In a previous study, we demonstrated that a robot model learned group norms in human groups [1]. In the present study, we investigate whether group norms occur in human–robot groups. To this end, we prepared quizzes with unclear and vague answers, and instructed participants to take the quizzes with the robot. The results of the quiz experiments demonstrated that the robot considered group norms in human–robot groups when making decisions; thus, group norms occurred in human–robot groups.
Improved Complex Skill Acquisition by Immersive Virtual Reality Training
Authors: Lohre Ryan , Bois Aaron J. , Athwal George S. , Goel Danny P. ,   on behalf of the Canadian Shoulder and Elbow Society (CSES)
Published: January 2020

Background:

There has been limited literature on immersive virtual reality (VR) simulation in orthopaedic education. The purpose of this multicenter, blinded, randomized controlled trial was to determine the validity and efficacy of immersive VR training in orthopaedic resident education.

Methods:

Nineteen senior orthopaedic residents (resident group) and 7 consultant shoulder arthroplasty surgeons (expert group) participated in the trial comparing immersive VR with traditional learning using a technical journal article as a control. The examined task focused on achieving optimal glenoid exposure. Participants completed demographic questionnaires, knowledge tests, and a glenoid exposure on fresh-frozen cadavers while being examined by blinded shoulder arthroplasty surgeons. Training superiority was determined by the outcome measures of the Objective Structured Assessment of Technical Skills (OSATS) score, a developed laboratory metric, verbal answers, and time to task completion.

Results:

Immersive VR had greater realism and was superior in teaching glenoid exposure than the control (p = 0.01). The expert group outperformed the resident group on knowledge testing (p = 0.04). The immersive VR group completed the learning activity and knowledge tests significantly faster (p < 0.001) at a mean time (and standard deviation) of 11 ± 3 minutes than the control group at 20 ± 4 minutes, performing 3 to 5 VR repeats for a reduction in learning time of 570%. The immersive VR group completed the glenoid exposure significantly faster (p = 0.04) at a mean time of 14 ± 7 minutes than the control group at 21 ± 6 minutes, with superior OSATS instrument handling scores (p = 0.03). The immersive VR group scored equivalently in surprise verbal scores (p = 0.85) and written knowledge scores (p = 1.0).

Conclusions:

Immersive VR demonstrated substantially improved translational technical and nontechnical skills acquisition over traditional learning in senior orthopaedic residents. Additionally, the results demonstrate the face, content, construct, and transfer validity for immersive VR.

Clinical Relevance:

This adequately powered, randomized controlled trial demonstrated how an immersive VR system can efficiently (570%) teach a complex surgical procedure and also demonstrate improved translational skill and knowledge acquisition when compared with a traditional learning method.
Successful Open Reduction and Internal Fixation of Proximal Humerus Fracture After Dysvascular Subcoracoid Humeral Head Dislocation
Authors: Douleh Diana G. , Stoneback Jason W. , Bravman Jonathan T.
Published: January 2020

Case:

We present the case of a 36-year-old patient with a 4-part proximal humerus fracture with subcoracoid dislocation and devascularization of the humeral head after a fall onto his right shoulder.

Conclusion:

The patient was successfully treated with open reduction and locking plate fixation to demonstrate that a successful postoperative functional outcome with humeral head survival can be achieved in these complex situations.
Ipsilateral Deltoid and Hand Compartment Syndrome
Authors: Kooner Sahil , Crocker Daniella , Matthewson Graeme , Byers Brett , Desy Nicholas M.
Published: January 2020

Case:

We present the unique case of deltoid and hand compartment syndrome in a young man after prolonged syncope because of polysubstance use. The patient was subsequently treated with urgent deltoid and hand compartment fasciotomies which resulted in full recovery of his shoulder function.

Conclusions:

Patients suspected of deltoid compartment syndrome should have a thorough physical examination, followed by repeat examinations. Invasive compartment monitoring should be used in equivocal cases, in patients with decreased level of consciousness, and in patients with distracting injury. Once diagnosed, deltoid compartment syndrome (± other compartments) should be taken for emergent fasciotomy, ensuring adequate decompression of all 3 deltoid compartments.
Study on Molecular Immunity Mechanism of Porcine Rotavirus VP6 Proteins expressed in Lactobacillus plantarum NC8
Authors: SHONYELA SERIA , Yang Wentao , Yang Guilian , Wang Chunfeng
Published: January 2020

The authors have withdrawn this preprint from Research Square
Type D personality and its impact on patients with Type 2 diabetes mellitus
Authors: Lin Yi-Hsin , Chen Di-An , Lin Chemin , Huang Hsuan
Published: January 2020

The authors have withdrawn this preprint from Research Square
Recombinant Porcine Rotavirus VP6 Proteins Expressed in Lactobacillus plantarum NC8 Strain Induces Specific Mucosal and Systemic Antibody Production in Experimental BALB/c mice
Authors: SHONYELA SERIA masole , Yang Wentao , Yang Guilian , Wang Chunfeng
Published: January 2020

The authors have withdrawn this preprint from Research Square
Design and analysis of driving motor system for hybrid electric vehicle
Authors: Chen Qiping , Wei Jiacheng , Zeng Fanhong , Xiao Qiang , Chen Hui
Published: January 2020

In order to improve the reliability and stability of hybrid electric vehicle driving motor system, according to the performance parameters of the hybrid electric vehicle, the driving motor system is designed and analyzed for the hybrid electric vehicle. Based on the performance parameters of the hybrid electric vehicle, the power parameters of the permanent magnet synchronous motor (PMSM) are calculated and determined, then the parameters of the stator core, the permanent magnet and the rotor core are designed and calculated, as well as other main characteristic parameters of the driving motor system are calculated. The model of a PMSM is established and simulated by ANSOFT Maxwell according to the obtained motor parameters, and then the steady state and transient state of the driving motor are simulated in different working points, and the electromagnetic and performance curves are combined to determine the overall performance requirements of the driving motor, which can be used to match the hybrid electric vehicle. The simulation results show that the designed PMSM can be used to match the hybrid electric vehicle and meet the performance requirements of the vehicle. The final simulation analysis results are in good agreement with the theoretical calculation results, which indicates that this method can be used to afford a theoretical basis to reduce the cogging torque and optimize the in-wheel motor of electric vehicle in the future.
Возможный вклад различных фаз в намагниченность спеченных материалов Nd-Dy-Fe-Co-B и ее температурную зависимость
Authors: Резчикова И.И. , Моисеева Н.С. , Королев Д.В. , Моргунов Р.Б. , Пискорский В.П.
Published: January 2020

Исследованы магнитные и структурные характеристики основных фаз, входящих в спеченные магнитотвердые материалы Nd-Dy-Fe-Co-B, а именно интерметаллидов (Nd0.33Dy0.67)1(Fe0.60Co0.40)4.74B1.12 и (Nd0.90Dy0.10)(Fe0.61Co0.39)3.13. Систематизированы параметры их элементарных ячеек и величины намагниченности насыщения при 80 и 350 K, а также температурная зависимость намагниченности в поле 800 kA/m в области от 320 до 600 K. Показано, что указанные соединения дают 10-15% вклад в намагниченность спеченных магнитов Nd-Dy-Fe-Co-B даже при их относительно невысоких концентрациях до 20%. Полученные данные дают возможность разделять вклады основной магнитной фазы от неосновных фаз в спеченных магнитах разного состава. Ключевые слова: спеченные магниты, удельная намагниченность насыщения, коэрцитивная сила по намагниченности, фазовый состав, неодим.
Особенности возбуждения линий главной серии атомов подгруппы цинка электронным ударом. I. Кадмий
Authors: Богачев Г.Г. , Ремета Е.Ю.
Published: January 2020

Using the technique of crossed beams of slow electrons and cadmium atoms, the excitation functions of three spectral lines of its principal series (166.9, 152.7, 146.9 nm) outgoing from the 5snp 1Po1 levels were measured (n = 6, 7, 8, respectively). In the range of electron energies 12–18 eV, a manifestation of the post-collision interaction of slow scattered electrons and fast electrons ejected during the decay of autoionizing states was found in these functions. This process, at incident electron energies of 11.8, 12.4, and 16.6 eV, leads to additional population of the initial levels of spectral transitions and, correspondingly, to maxima on the excitation functions due to the capture of a scattered electron to these excited levels. The terms of autoionizing states of the atom responsible for the observed maxima on the excitation functions of spectral lines are established. In the classical approximation, by two methods – direct calculation and least squares approximation – estimate the effective widths of the electronic decay of autoionizing states, the combined action of which leads to an energy shift of the maxima. Approximate calculation formulas are used, which are valid for various relations between the post-collision shift of the maxima on the excitation functions and the binding energy of atomic levels.
Многооконные акустооптические фильтры для корреляционной спектроскопии
Authors: Мазур М.М. , Судденок Ю.А. , Пожар В.Э.
Published: January 2020

We consider the problem of development of optical filters with synthesized transmission function. We demonstrate experimentally that acousto-optical tunable filters, which high-frequency control signal is generated digitally, is capable to synthesize various transmission functions: multi-band with adjustable location and bandwidth including asymmetric. And this fact open ways for complicated transmission function synthesizing.
Patient and Family Participation in Clinical Guidelines Development: The Cystic Fibrosis Foundation Experience (Preprint)
Authors: Hempstead Sarah E , Fredkin Kelsey , Hovater Cade , Naureckas Edward T
Published: January 2020

UNSTRUCTURED

Patient and family participation in guideline development is neither standardized nor uniformly accepted in the guideline development community, despite the 2011 Institute of Medicine’s Guidelines We Can Trust and the Guideline International Network’s GIN-Public Toolkit recommendations. The Cystic Fibrosis Foundation has included patients and/or family members directly in guideline development since 2004. Over time, various strategies for increasing patient and family member participation have been implemented. Surveys of recent patient/family and clinical guidelines committee members have shown that inclusion of individuals with cystic fibrosis and their family members on guidelines committees has provided insight otherwise invisible to clinicians.
DOES INTERNATIONAL TRADE AFFECT WELFARE? ECONOMIC FIQH ANALYSIS OF UMAR BIN KHATTAB
Authors: Muslikhati Muslikhati , Hakim Imamul
Published: January 2020

International trade in the era of globalization is essential. With international trade, the world economy becomes interconnected (Sharing economic) and interdependent. This study aims to find out and analyze how much influence international trade has on improving domestic welfare. The method used in this study is the PLS method, which is a type of multivariate research. International trade as an independent variable and welfare variable as the dependent variable is a construct of the overall model. Trade variables are indicated by FDI and Net export variables, while welfare variables are indicated by variables of income, consumption and wealth. From the results of this research, it was found that the construct variable namely international trade as an independent variable had a significant effect on the dependent variable, welfare. While the indicators for each variable, namely the value of FDI and Net exports, has a significant impact on international trade variables. Likewise with welfare indicators, namely the level of income, consumption and wealth also affect welfare.
Temporalidade descolonial em The Kissinger Project de Alfredo Jaar
Authors: San Martín Florencia , Melo Rafael , Leite Caroline Alciones De Oliveira , Oliveira Luiz Sérgio De
Published: January 2020

A partir de uma análise em uma perspectiva descolonial da obra do artista chileno Alfredo Jaar, mais especificamente The Kissinger Project, Florencia San Martín revisita alguns fatos históricos relevantes para a América do Sul, entre as décadas de 1970 e 1980, quando os regimes ditatoriais militares dominavam os países da região. No processo, esses regimes contaram com a participação/intervenção estado-unidense, tendo Henry Kissinger, então secretário de Estado, como personalidade política mais proeminente na defesa dos interesses das corporações dos Estados Unidos. No entanto, como nos alerta San Martín, “o econômico, o político e o social operam em conexão um com o outro”. Neste sentido, a ditadura militar chilena tinha na “implementação do livre mercado” um fator destacado em sua agenda política. San Martín nos recorda ainda que, assim como a modernidade, também a descolonialidade é um projeto inacabado. (Resumo e palavras-chave elaborados pelos editores)
Communication, Cyberculture and Cinema: Baudrillard and Matrix: "the limit point between two worlds"
Authors: Cardoso Luís Miguel Oliveira de Barros , Batista Margarida Cesário
Published: January 2020

Nowadays, we live in the so-called Network Society (Castells, 2003), a reality in which presence is no longer limited to physical places and begins to happen especially in virtual places. The online environment has come to emerge what is known as Cyberculture, a characteristic phenomenon of cyberspace and in which the pre-existing culture extends and renews itself and recreates itself. In this paper, we seek to explore the question of identity and the doubts that hang in the head of the human being about what is considered real or not, making use of the film The Matrix (1999), of the Wachowski brothers, where we will retrieve excerpts from the film and with which it can be connected with Simulacra and Simulation (1981).
A IMPLANTAÇÃO DOS PLANOS DE CULTURA NO ESTADO E NA CIDADE DE SÃO PAULO: HISTÓRICO, CONSTRUÇÃO E DESAFIOS
Authors: Queiroz Inti Anny
Published: January 2020

Os processos de implantação dos planos de cultura nos entes federados são parte relevante da estrutura do Sistema Nacional de Cultura, que depende dos mesmos para compor a descentralização territorial, a diversidade e a lógica de subsidiaridade da proposta.  Neste artigo apresentamos um panorama detalhado dessa construção no estado e município de São Paulo com vistas a demonstrar dois processos diferentes que ocorreram na mesma região do país e que em muitos momentos contou com agentes similares, tanto do governo quanto da sociedade civil. Trataremos dos processos a partir da observação histórica, relatando como ocorreram em cada ente federado. Observaremos as atividades e as dificuldades enfrentadas tanto por questões políticas quanto burocráticas e que vem impedindo a plena implantação dos sistemas de cultura territoriais. As atividades promovidas pelos movimentos das militâncias da cultura para tentar reverter as tentativas de desmonte também serão destacadas a fim de compreendermos a arquitetônica e as tensões na composição do sistema.
Metodologia participativa para elaboração de planos municipais de cultura: uma experiência aplicada
Authors: Rodrigues Luiz Augusto Fernandes , Correia Marcelo Silveira
Published: January 2020

Apresentação de metodologia participativa e integrada utilizada na elaboração de planos municipais de cultura. O trabalho relata experiência desenvolvida no estado do Rio de Janeiro, fruto de parceria técnica entre o Laboratório de Ações Culturais da Universidade Federal Fluminense (LABAC-UFF) e a Secretaria de Estado de Cultura do Rio de Janeiro (SEC-RJ), ação decorrente do programa PADEC – edição 2015. O artigo aponta parte do processo, breves relatos e reflexões sobre o tema
Plano de Cultura Infância do Ceará: um exercício de planejamento e resultado de escuta de demandas sociais
Authors: Lima Deborah Rebello , Costa Lilian Araripe Lustosa da
Published: January 2020

A breve análise apresentada neste artigo, trata o exemplo cearense, suas características e problematiza algumas particularidades do campo de políticas culturais num contexto mais recente. O Plano de Cultura Infância elaborado pelo governo do estado do Ceará pode ser um interessante exemplo de valorização de pautas da diversidade cultural e de fortalecimento de posturas da sociedade civil. Os resultados encontrados sinalizam uma peça de planejamento recém aprovada e que possivelmente ainda precisará de redirecionamentos.