bluuebunny/crossref_metadata_2025 huggingface dataset:
МЕНТАЛЬНО-АКСІОЛОГІЧНА УНІВЕРСАЛЬНІСТЬ ОБРАЗУ МАТЕРІ В МОВОТВОРЧОСТІ ПОЕТІВ-ШІСТДЕСЯТНИКІВ
Authors: СТЕЦИК Марія , СТЕЦИК Анастасія
Published: October 2023

У статті в лінгвостилістичному аспекті відрефлексовано експлікацію образу матері в мовотворчості українських поетів-шістдесятників І. Драча, Ліни Костенко, М. Вінграновського; зазначено, що у внутрішню форму імпліковані ментальні праглибини, простежено рецептивні стереотипи та ідіостильові особливості, що формують своєрідний матерецентризм авторського мовомислення (планетарність, позачасовість, позавимірність). Зроблено узагальнення, що ментально-аксіологічний лінгвофеномен образу матері найбільш універсально втілено в поезіях І. Драча, Ліни Костенко, М. Вінграновського.
СЛОВО В МОВІ: ЛЕКСИКОГРАФІЧНІ ТРАДИЦІЇ, ДОСВІД, ПЕРСПЕКТИВИ РОЗВИТКУ (РЕЦЕНЗІЯ НА ВИПУСК 31 ЗБІРНИКА НАУКОВИХ ПРАЦЬ «ЛЕКСИКОГРАФІЧНИЙ БЮЛЕТЕНЬ» ЗА РЕДАКЦІЄЮ Є.А. КАРПІЛОВСЬКОЇ)
Authors: ГІРНЯК Світлана
Published: October 2023

РЕЦЕНЗІЯ НА ВИПУСК 31 ЗБІРНИКА НАУКОВИХ ПРАЦЬ «ЛЕКСИКОГРАФІЧНИЙ БЮЛЕТЕНЬ» ЗА РЕДАКЦІЄЮ Є.А. КАРПІЛОВСЬКОЇ
ЛІНГВІСТИЧНІ ОСОБЛИВОСТІ ВЖИВАННЯ ІМЕННИКА МУДРІСТЬ: КОРПУСНОБАЗОВАНИЙ ПІДХІД
Authors: АЛЬБОТА Соломія , САБАН Олеся
Published: October 2023

Стаття спрямована на вивчення специфіки вживання іменника WISDOM (МУДРІСТЬ) в англійській мові у діахронії з використанням корпусного підходу. Дослідження охоплює два періоди часу, 1990–1994 та 2015–2019 роки, з використанням Corpus of Contemporary American English. У статті проаналізовано іменник WISDOM і колокації, які він утворює, та з’ясовано, що частотність його використання скоротилася у період з 2015 по 2019 роки, однак деякі колокації проявили протилежну тенденцію. Стаття акцентує увагу на важливості корпусного підходу у мовознавчих дослідженнях.
Impact of Concurrent Outbreaks of Livestock and Human Disease on Pork Consumer Price
Authors:   The Korean Agricultural Economics Association, Beom Jin-woo , Yoo Do-il
Published: October 2023

This study analyzes comprehensive impacts of concurrent outbreaks of African Swine Fever (ASF) and COVID-19 on pork consumer prices. For this study, we collect three time series data composed of the number of pigs culled by farms with ASF, the sentiment index for COVID-19 driven by big data sentiment analysis using on-line news texts, and the consumer price of pork belly. Autoregressive distributed lag (ARDL) models are constructed under three cases according to the presence of diseases. Results show the followings: first, the pork consumer price is affected negatively by ASF but positively by COVID-19. Second, the absolute impact of COVID-19 on price is bigger than that of ASF. Third, a comprehensive model considering both ASF and COVID-19 provides more reasonable results than models considering only one of both diseases.
PENGARUH CORPORATE GOVERNANCE, CASH FLOW, DAN BIAYA AGENSI MANAJERIAL TERHADAP FINANCIAL DISTRESS
Authors: Kusumawardhani Setyawan Nabila , Titik Aryati
Published: October 2023

Studi riset tersebut berusaha agar tahu pengaruh corporate governance, cash flow  dan biaya agensi manjerial pada financial distress, dengan menggunakan data perusahaan dari sektor food and beverages yang tercatat di Bursa Efek Indonesia. Kajian berdasarkan data dan informasi melalui Laporan keuangan dan lapran tahunan yang tersedia di laman valid Bursa efek Indonesia. Data yang dialanlisis pada riset ini yaitu data sekunder, dengan 65 sampel akhir yang dikumpulkan dengan menggunakan pendekatan purposive sampling antara tahun 2019 dan 2021. Pada riset ini, regresi linier logistik digunakan untuk analisis. Berdasarkan temuan penelitian ini, kepemilikan institusional dan dewan direksi mempunyai efek baik terhadap kesulitan keuangan. Sedangkan kepemilikan manajerial dan komite audit tidak berpengaruh. Komisaris independen dan cash flow menyatakan membawa dampak buruk pada keuangan. Namun, kontibusi positif biaya agensi manajerial terhadap gangguan keuangan
PENGARUH ANGGARAN PENDIDIKAN, ANGGARAN KESEHATAN, DAN TINGKAT KEMISKINAN TERHADAP INDEKS PEMBANGUNAN MANUSIA DI INDONESIA
Authors: Febrianto Mardika , Astrid Maria Esther
Published: October 2023

Tujuan dari penelitian ini adalah menganalisa pengaruh Anggaran Pendidikan, Kesehatan dan Tingkat Kemiskinan terhadap Indeks Pembangunan Manusia di Indonesia menggunakan regresi data panel. Data yang digunakan adalah data sekunder selama periode 2013-2023 yang berasal dari Badan Pusat Statistik (BPS) 34 Provinsi di Indonesia. Kesimpulan dari hasil penelitian ini adalah variabel Anggaran Pendidikan mempunyai pengaruh positif dan signifikan mempengaruhi IPM, Variabel Anggaran Kesehatan mempunyai pengaruh positif dan signifikan mempengaruhi IPM, Variabel Tingkat Kemiskinan memiliki pengaruh negatif dan signifikan mempengaruhi IPM. Data bersumber dari Kementrian keuangan dan Badan Pusat Statistika.
Up Front and Open? Shrouded in Secrecy? Or Somewhere in Between? A Meta-Research Systematic Review of Open Science Practices in Sport Medicine Research
Authors: Bullock Garrett S. , Ward Patrick , Impellizzeri Franco M. , Kluzek Stefan , Hughes Tom , Hillman Charles , Waterman Brian R. , Danelson Kerry , Henry Kaitlin , Barr Emily , Healy Kelsey , Räisänen Anu M. , Gomez Christina , Fernandez Garrett , Wolf Jakob , Nicholson Kristen F. , Sell Tim , Zerega Ryan , Dhiman Paula , Riley Richard D. , Collins Gary S.
Published: October 2023

OBJECTIVE: To investigate open science practices in research published in the top 5 sports medicine journals from May 1, 2022, and October 1, 2022.

DESIGN: A meta-research systematic review.

LITERATURE SEARCH: Open science practices were searched in MEDLINE.

STUDY SELECTION CRITERIA: We included original scientific research published in one of the identified top 5 sports medicine journals in 2022 as ranked by Clarivate: (1) British Journal of Sports Medicine, (2) Journal of Sport and Health Science, (3) American Journal of Sports Medicine, (4) Medicine and Science in Sports and Exercise, and (5) Sports Medicine-Open. Studies were excluded if they were systematic reviews, qualitative research, gray literature, or animal or cadaver models.

DATA SYNTHESIS: Open science practices were extracted in accordance with the Transparency and Openness Promotion guidelines and patient and public involvement.

RESULTS: Two hundred forty-three studies were included. The median number of open science practices in each study was 2, out of a maximum of 12 (range: 0-8; interquartile range: 2). Two hundred thirty-four studies (96%, 95% confidence interval [CI]: 94%-99%) provided an author conflict-of-interest statement and 163 (67%, 95% CI: 62%-73%) reported funding. Twenty-one studies (9%, 95% CI: 5%-12%) provided open-access data. Fifty-four studies (22%, 95% CI: 17%-27%) included a data availability statement and 3 (1%, 95% CI: 0%-3%) made code available. Seventy-six studies (32%, 95% CI: 25%-37%) had transparent materials and 30 (12%, 95% CI: 8%-16%) used a reporting guideline. Twenty-eight studies (12%, 95% CI: 8%-16%) were preregistered. Six studies (3%, 95% CI: 1%-4%) published a protocol. Four studies (2%, 95% CI: 0%-3%) reported an analysis plan a priori. Seven studies (3%, 95% CI: 1%-5%) reported patient and public involvement.

CONCLUSION: Open science practices in the sports medicine field are extremely limited. The least followed practices were sharing code, data, and analysis plans. J Orthop Sports Phys Ther 2023;53(12):735-747. Epub 20 October 2023. doi:10.2519/jospt.2023.12016
Pathogenesis and descriptions of amblyopia. Part 2. Analysis of definitions
Authors:   Morozov Children's Clinical Hospital, Moscow, Russian Federation, Khatsenko I.E. , Rozhkova G.I. ,   Institute for Information Transmission Problems (Kharkevich Institute) RAS, Moscow, Russian Federation, Gracheva M.A. ,   Institute for Information Transmission Problems (Kharkevich Institute) RAS, Moscow, Russian Federation, Salmasi J.M. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Balashova L.M. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation,   International Scientific and Practical Center for Tissue Proliferation, Moscow, Russian Federation
Published: October 2023

This article describes the definitions of amblyopia appearing in the literature and discusses how exacly they reflect modern ideas about the disease. Based on the results of the analysis, it is recommended not to use the widespread expression “lazy eye” as a synonym for amblyopia, since it distorts the essence of this disease. Two alternative ways of searching for a modern correct definition of amblyopia are proposed. Key words: correct definition of amblyopia, concept of amblyopic component, lazy eye syndrome
Transcilliary drainage of posterior chamber in the treatment of angle-closure glaucoma
Authors:   S. Fyodorov Eye Microsurgery Federal State Institution, Moscow, Russian Federation, Kozlova E.E. , Slastina K.I. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Moscow, Russian Federation
Published: October 2023

The review presents the main existing transcilliary drainage of posterior chamber (TDPC) methods used nowadays. We tried to analyze existing key articles and patents issued for methods of treating glaucoma. Based on the literature data, we found that TDPC is a safe and effective method for the treatment of angleclosure glaucoma, and application of various parameters of laser energy and drainage process increase efficiency of this procedure. At the same time, the rapid progression of the glaucoma process requires constant improvement of modern TDPC techniques. Key words: angle-closure glaucoma, transciliary drainage of the posterior chamber
Evaluation of intraocular lens displacement with ultrasound biomicroscopy data
Authors:   Department of Ophthalmology of the Medical Academy named after S.M. Kirov, St. Petersburg, Dzilikhov A.A. , Danilenko E.V. ,   Department of Ophthalmology of the Medical Academy named after S.M. Kirov, St. Petersburg
Published: October 2023

Purpose. To analyze the postoperative IOL displacements toward the haptic plane using ultrasound biomicroscopy (UBM). Material and methods. Biometry data of 172 patients (211 eyes) 71.32 ± 7.75 years old were analyzed, among whom 41.25% were men. IOL position were analyzed at 1 and 3 months after standard phacoemulsification. Results. The IOL was visualized with UBM. Stabilization of lens position was observed by the 3rd month of observation. The displacement of optical part IOL in forward was determined in 24.95%, backward – in 16.57% of cases. Eyes with opposite IOL displacements differed significantly in crystalline lens diameter, ciliary sulcus diameter and the power of implanted IOL. Conclusions. An important technique in the search for possible causes of changes in postoperative refraction is visualization of IOL displacement. The number of displacements of the intraocular lens increases by 3 months, which may cause in visual acuity changes. Keywords: Intraocular lens (IOL) optical part displacement, ultrasound biomicroscopy (UBM), phacoemulsification
Experience in the use of intraocular lenses with deep focus in patients operated on for retinal detachment
Authors:   OOO «Medstandart», Irkutsk, Patrikeeva A.G. , Novolodskii A.I. ,   OOO «Medstandart», Irkutsk, Burii V.V. ,   OOO «Medstandart», Irkutsk
Published: October 2023

There is currently insufficient evidence in the literature on the implantation of a deep focus IOL in patients with retinal detachment during cataract surgery or second-stage cataract surgery. In the course of the study, it was found that visual acuity at distance and near in patients operated on for retinal detachment, cataracts with implantation of intraocular lenses with deep focus is lower than visual acuity at the same distances in patients operated on for cataracts with EDOF IOL implantation, and the degree of satisfaction and the presence of optical phenomena are almost identical. Keywords: retinal detachment, deep focus IOL.
Analysis of intraoperative and early postoperative complications in cataract phacoemulsification
Authors:   State Budgetary Institution “N.A. Semashko Regional Clinical Hospital” Ryazan, Russia, Solomatina M.V. , Kolesnikov A.V. ,   State Budgetary Institution “N.A. Semashko Regional Clinical Hospital” Ryazan, Russia,   Ryazan State Medical University, Ryazan, Russia, Mironenko L.V. ,   State Budgetary Institution “N.A. Semashko Regional Clinical Hospital” Ryazan, Russia,   Ryazan State Medical University, Ryazan, Russia, Nikolaev M.N. ,   State Budgetary Institution “N.A. Semashko Regional Clinical Hospital” Ryazan, Russia, Kirsanova I.V. ,   State Budgetary Institution “N.A. Semashko Regional Clinical Hospital” Ryazan, Russia,   Ryazan State Medical University, Ryazan, Russia
Published: October 2023

Relevance. Despite the high level of cataract surgery, in some cases complications arise that lead to a decrease in visual functions, an increase in the duration of inpatient treatment and additional economic costs. Analysis of the results of cataract phacoemulsification helps to increase the effectiveness of predicting complications and their prevention. Aim. Analysis of intraoperative and early postoperative complications in cataract surgery for 2021–2022, conducted on the basis of the 2nd ophthalmological department of the State Budgetary Institution “N.A. Semashko Regional Clinical Hospital” Ryazan, Russia. Material and methods. Retrospective analysis of 66 case histories of patients who had complications in the intra- and postoperative period of cataract surgery. Results. Intraoperative complications included: posterior capsule opening (22 cases), dislocation of lens masses into the vitreal cavity (10 cases), hemorrhagic ciliochoroidal detachment (4 cases), expulsive hemorrhage (2 cases), hyphema (2 cases). In the postoperative period, the following complications were detected: hyphema – 2, hemophthalmos-4, ciliochoroidal detachment – 5, dislocation of intraocular lens (IOL) – 5, retained lenticular material in the anterior chamber – 4, exudative reaction – 12, keratopathy – 6, pupillary block – 1, endophthalmitis – 1. Conclusion. The improvement of the phacoemulsification technique together with the preoperative preparation of patients with cataracts made it possible to achieve a low level of intra- and postoperative complications (1.16% in 2021 and 0.89% in 2022, respectively, of all operated patients with cataracts). However, after analyzing the nature of complications, we identified a number of patterns: among intraoperative complications, the most common is the opening of the posterior capsule of the lens (0,29%), among postoperative – an exudative reaction (0,16%). Keywords: сataract phacoemulsification, complications of cataract phacoemulsification, rupture of the posterior lens capsule, exudative inflammatory eye response, expulsive hemorrhage.
Comparative analysis of the functional results after implantation of various EDOF IOL models
Authors:   LLC «Eye Clinic «Lege Аrtis», Rostov-on-Don, Temirov N.E. , Temirov N.N. ,   LLC «Eye Clinic «Lege Аrtis», Rostov-on-Don
Published: October 2023

The aim of the current work is a comparative assessment of extended focus intraocular lenses (IOL) based on the most important criteria for the patient – visual acuity at different distances and the pattern of subjective visual sensation The following IOL models were compared: Comfort (Teleon), Tecnis Symfony (J&J), Ac.JQ Vivity (Alcon), Ray One EMV (Rayner), Tecnis Eyhance (J&J), Lux Smart (Bausch & Lomb). 180 patients were under observation after phacoemulsification, with bilateral implantation of the above named IOL. All patients were divided into 6 groups depending on the type of lenses, their visual acuity at various distances was determined in the postoperative period and they were asked to fill out a 14-questions questionnaire. Conclusions. Visual functions in patients after IOL implantation were slightly different from one another, which makes it possible to recommend them differentially to each patient depending on his age, gender, occupation and habits. Implantation of the IOL Comfort with a low addition more often than other lenses provides better visual acuity at a short distance, however distance visual acuity usually does not reach its maximum values. One fourth of patients with the IOL Comfort report halos and spots of light in the dark. Distance visual acuity is the highest in case of Symfony, Vivity, Eyehance IOL implantation, however, at medium and close distances it is usually insufficient for reading of an ordinary text. One third of patients with Symfony IOL implantation report halos around light sources in the dark. Lenses with a dosed combination of spherical aberrations (Ray One EMV, Lux Smart) are characterized by highly balanced values of visual acuity at different distances. There are complaints of light phenomena at night, but they are minimal. Keywords: cataract, presbyopia, IOL with extended focus.
Сomparative evaluation of the effectiveness of surgical treatment of keratoconus by a combined method
Authors:   Tashkent State Dental Institute, Tuychibaeva D.M. , Kim A.A. ,   Tashkent State Dental Institute
Published: October 2023

Relevance. Keratoconus is a common asymmetric and usually bilateral ectatic corneal disease characterized by progressive corneal protrusion, resulting in reduced visual acuity and deterioration of optical properties. Purpose of the study. To evaluate the effectiveness of surgical treatment of keratoconus with various combined methods. Material and methods. The article presents a comparative analysis of data from patients with II and III stages of keratoconus (52 patients, 66 eyes) after implantation of intrastromal corneal ring segments with femtosecond accompaniment, followed by corneal crosslinking and corneal crosslinking, followed by implantation of intrastromal corneal ring segments with femtosecond accompaniment. Results and conclusion. The refractive result for the spherical and cylindrical components gave the best result in group 2, in which stage 1 was implantation of ICRS, and stage 2 was corneal collagen crosslinking, compared with group 1, in which stage 1 was corneal collagen crosslinking, and stage 2 was implanted ICRS. Progression stopped in 65 cases. Keywords: keratoconus, intrastromal corneal segments, femtosecond laser, corneal crosslinking.
Features of cataract phacoemulsification and IOL calculation in patients with high degree hypermetropia
Authors:   Irkutsk Branch of S. Fyodorov “Eye Microsurgery” Federal State Institution, Irkutsk, Russian Federation, Mishchenko O.P. , Zaitseva K.A. ,   Irkutsk Branch of S. Fyodorov “Eye Microsurgery” Federal State Institution, Irkutsk, Russian Federation, Iureva T.N. ,   Irkutsk Branch of S. Fyodorov “Eye Microsurgery” Federal State Institution, Irkutsk, Russian Federation,   Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Russian Medical Academy of Continuing Professional Education, Irkutsk, Russian Federation,   Irkutsk State Medical University, Irkutsk, Russian Federation
Published: October 2023

Despite the fact that phacoemulsification is a standard operation, in patients with high hypermetropia, this procedure may be accompanied by complications associated with a short axial axis of the eyeball, a small anterior chamber, as well as IOL calculation errors. Purpose. To evaluate the results of cataract surgical treatment and the accuracy of IOL calculation in patients with high-grade hypermetropia. Materials and methods. 34 patients (49 eyes) with high-grade hypermetropia who underwent cataract surgery with IOL implantation under observation were included. The comparison of uncorrected (UCVA) and corrected (BCVA) visual acuity, spherical refraction equivalent, IOP before surgery, at discharge, 1 and 6 months after surgery was carried out. Results. There was an increase in UCVA to 0.47 ± 0.13 and BCVA to 0.64 ± 0.21, as well as a decrease in the refractive index to –0.03 ± 0.29 in the postoperative period. The average IOP values after surgery in this sample of patients decreased from 14.45 ± 3.40 to 12.83 ± 5.04, and remained stable throughout the follow-up period. However, a significant refractive error of the IOL calculation was noted in one case, and an increase in IOP with the development of the posterior block in 1 case. These conditions required additional interventions and were stopped. Conclusion. Phacoemulsification with IOL in hypermetropia of a high degree improves the visual functions of this category of patients. It is necessary to take into account the short axial length of the eyeball when calculating the IOL and use several modern formulas. At the same time, the possibility of refractive error cannot be completely excluded, which should be discussed with the patient at the stage of planning the operation. Key words: phacoemulsification, hypermetropia, biometrics, IOL
Factors affecting safe driving habits
Authors:   The Korean Association of Criminal Psychology, Baek Ju Min
Published: October 2023

Unsafe driving habits cause violent driving, speeding, and violations of laws. Therefore, this habits are risk factors for all road users, including drivers and pedestrians. Cars are described as a comfortable means of transportation for modern people and a collection of science and technology that improves the quality of life, but media reports on traffic accidents continue even today. Current study empirically reviewed the impact on safe driving habits by setting demographic variables and traffic accident experiences variables based on literature that reviewed factors affecting safe driving habits. In addition, the driver's satisfaction with insurance was set as a variable to explore the impact of insurance satisfaction on safe driving habits. Specifically, the judgement fairness of accident, insurance costs and procedural satisfaction on drivers' safe driving habits was verified through multiple regression analysis. As a result of the study, it was confirmed that gender, age, and traffic accident experiences had statistically significant effects on safe driving habits. On the other hand, only judgement fairness of accident among insurance satisfaction had statistically significant effect on safe driving habits. Based on these results, the policy implications for promoting safe driving habits were discussed.
Modern approaches to digital product development in the conditions of market variability
Authors: Vasilieva E. V. , Morev E. A.
Published: October 2023

Currently, the interest in design thinking in the world has made it possible to add many techniques and visual schemes that can solve various kinds of problems, including for building a strategy to achieve the company’s goals, its corporate spirit and the development of creative skills of its employees. Already today, it is possible to call the merit of design thinking the shift of emphasis in corporate goals to customer orientation, to the mobilization of collective intelligence to solve problems, to understanding the importance of empathy, creativity and entrepreneurship. A comparative analysis of existing design thinking frameworks is given, including from researchers of companies and design centers such as Hasso Plattner Institute of Design at Stanford University (d.school), The HPI-Stanford Design Thinking Research Program, Stanford d.school’s Design Thinking framework (IDEO), Google, Intel. Frameworks structure the process of design thinking in 5-6 phases: from empathy, when the needs and requests of consumers are studied, to testing an innovative product or service being created. The place of “design thinking” approach in the general concept of human-centered design is shown. The task of design thinking, the development of innovative products or services focused on human needs, is to provide a solution to a specific problem of a certain target audience. The paper outlines the principles of designing a digital innovative product. The five steps of designing a new product are described and the features of using various visualization techniques are given. The study uses such tools as the “Persona” model, Job Stories and User Stories frameworks. The creating process features of an innovative product based on the integration of design thinking, Lean Startup methodology and the theory of Jobs to Be Done are described. The life cycle of the innovation development “Creation – Evaluation – Training” is presented which is based on the process of validated learning. Changes in the outline of the business model in the lean startup methodology are presented. New segments have been added to the Lean Canvas business model – “Key Partners”, “Key Activities”, “Key Resources”, “Consumer Relations”.
Impact of human potential quality indicators on the regional economy development
Authors: Ostapenko E. A.
Published: October 2023

The article provides an assessment of the quality of human potential, which includes the use of the most effective indicator, on the basis of which it is possible to analyze the standard of living of citizens - the human development index, in relation to the constituent entities of the Russian Federation. In the course of the analysis, priority directions for the development of the constituent entities of the Russian Federation were identified and regularities were determined. The elements on the basis of which one can judge the quality of human potential in modern economic and social conditions are considered and defined. The purpose of the study is to analyze and evaluate the relationship between the components of the quality of human potential and development indicators of the constituent entities of the Russian Federation. The objectives of the study are to form an assessment of the quality of human potential in the context of the regional economy, using the HDI indicator. In the course of the study, methods of a general scientific and special nature were used: analysis, synthesis, abstraction, induction and deduction. In the course of the study, it was possible to form a model consisting of several indicators, on the basis of which a conclusion was made about the existing level of human potential of citizens of the Russian Federation. The practical significance of the study lies in the possibility of using its results in shaping the development paths of the regions of the Russian Federation.
Market ranking of successful digital business models
Authors: Denisova A. L. , Lopatnikov A. N. , Rumyantsev A. Yu.
Published: October 2023

The transition from industrial to service economy resulted in a wider adoption of asset-light strategies and technology-enabled business models. In the last ten years, digital companies have ascended to the top of the most valuable firms lists. Various aspects of digital business models have been exhaustively discussed in management literature, but their economic dimension remains under-researched.We analyze how strategy and business model add value and propose using historical volatility of valuation multiples for ranking companies by the degree of investors’ understanding of a firm’s strategy and business model in addition to ratings of companies by market capitalization. This ranking, in our view, is particularly helpful in analyzing business models of digital companies where most of the value is in intangible assets and economic goodwill. We also propose a way of expanding this research topic in the future.
Urban Regeneration for Crime Rate Reduction: A Case Study of Mitte District, Berlin, Germany
Authors:   KOREA CPTED ASSOCIATION, Park Jong-Ki , Seo Eu-Gene
Published: October 2023

Urban regeneration plays a pivotal role in enhancing urban safety and residents' quality of life while being closely linked to reducing urban crime rates through transformative changes in city spaces. The improvement of infrastructure, parks, and public facilities connected to residential areas has a profound impact on addressing urban crime issues within communities.
This study focuses on Mitte, a district in the German capital Berlin, where successful crime rate reduction was achieved through urban regeneration initiatives in high-crime areas. The research conducts a comprehensive case analysis of urban regeneration plans and strategies to identify the specific attributes contributing to crime reduction and the strategic approaches used for crime prevention environment design. The analysis of Mitte's Leopolaplatz area reveals two distinct features of crime prevention environment design implemented through urban regeneration: physical space rejuvenation and enhanced social integration. The rejuvenation of physical spaces involves a clear distinction between private and public areas. The findings of the analysis are as follows: Firstly, urban regeneration of private spaces results in an improvement in residents' sense of ownership and increased surveillance. Secondly, the regeneration of public spaces strengthens their identity and image, promoting a more organic form of surveillance. Lastly, the physical urban regeneration of both private and public spaces contributes to a safer urban environment. The implementation of community strengthening programs further enhances community cohesion.
The Effect of CPTED Elements and Crime Prediction by Using Big Data Analysis in Seoul
Authors:   KOREA CPTED ASSOCIATION, Lee Seo-el , Lee Yae-eun , Hwang EuiGab
Published: October 2023

In various parts of the world, big data related methods is being utilized to predict criminal activities and facilitate prompt arrests. Advancements in big data and technology have made it possible to analyze and forecast crime patterns effectively. This research aims to analyze the effectiveness of Crime Prevention Through Environmental Design (CPTED) elements and predict crime rates using machine learning techniques based on data from 2016 to 2021 in Seoul. This study utilizes diverse data in CPTED elements obtained from the Smart Public Safety Big Data Platform. The significance of this study lies in demonstrating the effectiveness of CPTED and leveraging big data for crime prediction. The findings can serve as a reference for the policy-making and the establishment of crime prevention systems based on predictive insights.
Role of ciliopathy protein TMEM107 in eye development: insights from a mouse model and retinal organoid
Authors: Dubaic Marija , Peskova Lucie , Hampl Marek , Weissova Kamila , Celiker Canan , Shylo Natalia A , Hruba Eva , Kavkova Michaela , Zikmund Tomas , Weatherbee Scott D , Kaiser Jozef , Barta Tomas , Buchtova Marcela
Published: October 2023

Primary cilia are cellular surface projections enriched in receptors and signaling molecules, acting as signaling hubs that respond to stimuli. Malfunctions in primary cilia have been linked to human diseases, including retinopathies and ocular defects. Here, we focus on TMEM107, a protein localized to the transition zone of primary cilia. TMEM107 mutations were found in patients with Joubert and Meckel–Gruber syndromes. A mouse model lackingTmem107exhibited eye defects such as anophthalmia and microphthalmia, affecting retina differentiation.Tmem107expression during prenatal mouse development correlated with phenotype occurrence, with enhanced expression in differentiating retina and optic stalk. TMEM107 deficiency in retinal organoids resulted in the loss of primary cilia, down-regulation of retina-specific genes, and cyst formation. Knocking out TMEM107 in human ARPE-19 cells prevented primary cilia formation and impaired response toSmoothenedagonist treatment because of ectopic activation of the SHH pathway. Our data suggest TMEM107 plays a crucial role in early vertebrate eye development and ciliogenesis in the differentiating retina.
Pathway-driven analysis of synthetic lethal interactions in cancer using perturbation screens
Authors: Karimpour Mina , Totonchi Mehdi , Behmanesh Mehrdad , Montazeri Hesam
Published: October 2023

Synthetic lethality offers a promising approach for developing effective therapeutic interventions in cancer when direct targeting of driver genes is impractical. In this study, we comprehensively analyzed large-scale CRISPR, shRNA, and PRISM screens to identify potential synthetic lethal (SL) interactions in pan-cancer and 12 individual cancer types, using a new computational framework that leverages the biological function and signaling pathway information of key driver genes to mitigate the confounding effects of background genetic alterations in different cancer cell lines. This approach has successfully identified several putative SL interactions, includingKRAS-MAP3K2andAPC-TCF7L2in pan cancer, andCCND1-METTL1,TP53-FRS3,SMO-MDM2, andCCNE1-MTORin liver, blood, skin, and gastric cancers, respectively. In addition, we proposed several FDA-approved cancer-targeted drugs for various cancer types through PRISM drug screens, such as cabazitaxel forVHL-mutated kidney cancer and alectinib for lung cancer withNRASorKRASmutations. Leveraging pathway information can enhance the concordance of shRNA and CRISPR screens and provide clinically relevant findings such as the potential efficacy of dasatinib, an inhibitor ofSRC, for colorectal cancer patients with mutations in the WNT signaling pathway. These analyses revealed that taking signaling pathway information into account results in the identification of more promising SL interactions.
Exploring Children’s Learning through Teachers' Agential Cuts: Moving Towards Differentiation in Learning
Authors:   Korean Society for Young Children Becoming Curriculum, Kim Gunhee , Park Seonyoung , Jung Hyeyoung
Published: October 2023

This paper explored children's learning through the agential cuts of teachers. In order to approach the learning of children who are intricately intertwined with time, space, and materials, researchers attempted arbitrary separation through ‘agential cuts.’ The intensity of the affect was determined in the assemblage of all elements, including past memories, attitudes of listening to each other, and texts exchanged by researchers to respond to research questions. And the researchers' cuts were placed as “learning that starts from children's desires”, “emerging children’s culture and learning”, and “learning as a response to the world”. The discussion focusing on the assemblage of these agential cuts is as follows. First, children learn by encountering and reacting with the world's materials in a way that has never been done before, and by producing differentiation on their own. Second, teachers participate in the children's world and practice pedagogical actions through agential cuts to reach the uncertain learning of children who learn anew by creating differentiation every moment. These teachers' praxis can be seen as responding to ethical requests for entangled phenomena. This study is meaningful in that it has taken a step inside the phenomenon through agential cuts to approach the reality of learning that endlessly creates differentiation. It also show the new relocation that emerges from the relationship by crossing the boundaries of learning and teaching that creates differences will provide implications for the direction of early child teacher education.
КЛАСТЕРНЫЕ КОМПЛЕКСЫ РЕНИЯ С ПОЛИБОРГИДРИДНЫМИ АНИОНАМИ [Re6S8(Me2PzH)6]X (X = B10H10, B12H12)
Authors: Давыдова М.П. , Сухих Т.С. , Рахманова М.И. , Брылев К.А. , Артемьев А.В.
Published: October 2023

Обменным взаимодействием [Re6S8(Me2PzH)6]Br2 с K2B10H10 и (Et3NH)2B12H12 синтезированы ранее неизвестные гибридные соединения [Re6S8(Me2PzH)6][B10H10] (1) и [Re6S8(Me2PzH)6][B12H12] (2), сочетающие в своей структуре металлокластерные катионы [Re6S8(Me2PzH)6]2+ и полиборгидридные кластерные анионы [BnHn]2− (n = 10, 12). В кристаллах синтезированных соединений ионы образуют 3D супрамолекулярную структуру за счет коротких контактов H−B···H−C. При комнатной температуре указанные соединения проявляют красную фосфоресценцию с λмакс. = 680 (1) и 670 (2) нм, соответственно.
Effects of Insecticide-Treated Nets and Stagnant Water on the Risk of Malaria: A Meta-Analysis
Authors: Minawati Atika Dwi , Ramadhani Dinda Nur Asri Mutiara , Damayanti Siti , Ariska Yovita Galuh Eka , Murti Bhisma , Handayani Anggun Fitri
Published: October 2023

Background: Malaria infection is a global public health problem that causes major morbidity worldwide. Stagnant water is one of the risk factors for malaria, insecticide-treated nets are one of the interventions that can prevent malaria. This study aims to estimate the magnitude of the effect of using insecticide-treated nets and stagnant water around the house on the risk of malaria.
Subjects and Method: This study was conducted using a systematic review and meta-analysis with PICO, Population: children. Intervention: insecticide-treated mosquito nets and stagnant water. Comparison: without insecticide-treated nets and no stagnant water. Result: incidence of malaria. By searching for articles in 3 databases namely PubMed, Google Scholar, and Science Direct published from 2016 to 2023, by entering the following keywords insecticide-treated bed nets” OR “ITN” AND “stagnant water” OR “STAGNA” AND “Malaria” AND “Cross-sectional” AND “Multivariate Analysis”. Articles were selected using the PRISMA flow and data analysis using the Review Manager 5.3.
Results: There are 13 articles using a cross-sectional study design with a total sample of 5,793 children from Indonesia, Cameroon, Nigeria, and Ethiopia which have gone through a systematic review and meta-analysis. Processed data showed that children who used insecticide-treated nets had a 0.65 times lower chance of contracting malaria compared to those who did not use insecticide-treated nets (aOR= 0.65; 95% CI= 0.41 to 1.01; p= 0.060). Children who live in an environment where there is stagnant water have a 4.10 times chance of getting malaria compared to children who live in an environment where there is no stagnant water and this is statistically significant (aOR= 4.10; 95% CI= 2.80 to 6.03; p <0.001).
Conclusion: Insecticidal mosquito nets reduced the incidence of malaria, and stagnant water increased the incidence of malaria.
Keywords: insecticide-treated nets, stagnant water, STAGNA, children
Correspondence: Atika Dwi Minawati. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir Sutami No.36, Kentingan, Jebres, Surakarta, 57126, Central Java. Email: dwiminawatiatika@gmail.com. Mobile: +625212613303.
The Effect of Neoalgae Spirulina Supplements Intakes on Increasing Body Height and Weight of Stunting Children in Mranggen, Sukoharjo, Central Java
Authors: Ani Nur , Maharani Nine Elissa , Nugraho Farid Setyo , Rahardjo Budhi , Utami Amrih Gancar
Published: October 2023

Background: Children who are stunted have a higher risk of experiencing health and brain development disorders, and have a lower likelihood of achievement and a bright future. Spirulina is one of the food sources enriched with nutrients that affect the nutritional status of children. The study aims to discover the effect of the administration of Spirulina Neoalgae supplements on increasing the height and weight of stunting toddlers in Mranggen village.
Subjects dan Method: The study used a quasi-experimental design conducted in Mranggen Village, Sukoharjo, Central Java. A total of 100 toddlers selected using total sampling were included in this study. The independent variable in this study was the intervention of Spirulina Neoalgae supplements and the dependent variables in this study were body weight and height. Toddlers were given supplement interventions for 4 weeks. The collected data were subsequently analyzed using the Paired-Test.
Results: Before the intervention the average height was (Mean= 82.92; SD = 8.77) and body weight was (Mean= 9.97; SD= 2.09). After the supplement intervention for 2 weeks, the average height was (Mean= 83.56; SD = 8.61) and body weight was (Mean= 10.11; SD= 2.07). Average height (Mean= 84.56; SD= 8.57) and body weight (Mean= 11.04; SD = 2.10) in week four increased and the result was statistically significant (p >0.001).
Conclusion: The administration of neoalgae supplements affects increasing height and weight in stunted children in Mranggen Village, Sukoharjo, Central Java.
 
Keywords: Supplements, Neoalgae, Nutritional Status, Height, Weight, Stunting
Meta-Analysis of the Effectiveness of Teledentistry on Patients Satisfaction
Authors:   Masters Program in Public Health, Universitas Sebelas Maret, Utsani Wimmy Safaati , Demartoto Argyo ,   Faculty of Social and Political Sciences, Universitas Sebelas Maret, Murti Bhisma ,   Masters Program in Public Health, Universitas Sebelas Maret
Published: October 2023

Background: Preventive strategies of caries prevention, such as topical fluoridation or drinking water, have been effective in inhibiting the development of carious lesions. Teledentistry is an alternative service that combines dentistry with long-distance telecommunication technology for consultation and treatment planning that can be used for dental and oral health education to increase public awareness. The purpose of this study was to analyze the effectiveness of teledentistry on patient satisfaction. Subjects and Method: This study was a meta-analysis with the following PICO, population: patients. Intervention: teledentistry. Comparison: conventional (outpatient). Outcome: patients satisfaction. The articles used in this study were obtained from three databases, namely Google Scholar, Pubmed, and Science Direct. Keywords to search for articles are “teledentistry” OR “oral hygiene” AND “multimedia” OR “smartphone app” OR “online social media” AND “patient satisfaction”. The articles included are full text English with a randomized control trial study design from 2013 to 2023. The selection of articles was carried out using the PRISMA flow diagram. Articles were analyzed using the Review Manager 5.3 application. Results: A total of 9 case studies from the continents of Europe (Netherlands, Germany, Italy), North America (Pennsylvania), and Asia (India, Saudi Arabia, Iran) were selected for systematic review and meta-analysis. The results showed that 1.05 units of teledentistry increased patient satisfaction compared to not being given teledentistry. Statistical results (SMD = 1.05; 95% CI= 0.64 to 1.46; p < 0.001). Conclusion: Teledentistry increased patient satisfaction Keywords: teledentistry, oral hygiene, online social media, patients satisfaction
Highly pathogenic avian influenza A(H5N1) virus infection in foxes with PB2-M535I identified as a novel mammalian adaptation, Northern Ireland, July 2023
Authors: Lagan Paula , McKenna Robyn , Baleed Salam , Hanna Bob , Barley Jason , McConnell Shirley , Georgaki Anastasia , Sironen Tarja , Kauppinen Ari , Gadd Tuija , Lindh Erika , Ikonen Niina , McMenamy Michael J , Lemon Ken
Published: October 2023

We report cases of mammalian infection with highly pathogenic avian influenza (HPAI) virus A(H5N1) clade 2.3.4.4b in Northern Ireland. Two common gulls (Larus canus) and two red fox kits (Vulpes vulpes), were found dead in close vicinity. Comparison of viral whole genome sequences obtained from the animals identified a novel mammalian adaptation, PB2-M535I. Analysis of genetic sequences from other recent mammalian infections shows that this mutation has arisen on at least five occasions in three European countries since April 2023.
What kinds of educational material are useful for and desired by university instructors? The case of Geotechnical Engineering
Authors: Pantazidou Marina , Calvello Michele
Published: October 2023

Αn online questionnaire was developed to find out (i) whether geotechnical engineering instructors have available a variety of satisfactory educational material and (ii) the types of educational material they desire. The title of the questionnaire was phrased as “What Geotechnical Engineering Educational Material can we dream of?”, in order to convey that the main purpose of the survey project reported herein is to learn about these desired educational materials. In doing so, the survey also aims to assemble information on related issues, such as: existing educational materials, where do instructors search for them and how satisfied they are with available material. The questionnaire has 12 close-ended (four yes/no and eight multiple choice) and four open-ended questions. From the 94 completed questionnaires received, 63 were deemed to be conscientious attempts to answer its questions and were analyzed in detail. The most revealing findings from the close-ended questions include the following. The majority of the instructors (52%) are not adequately satisfied with the material they use. Likewise, whereas a significant percentage has searched for additional material, a little less than half of them (45%) are not satisfied with material found. Respondents need materials for their lectures, materials to engage students outside lecture time and, to a lesser extent, materials to assess students. In terms of topics of interest, case studies and laboratory-related educational materials are the most popular. The online supplement of the paper includes broad-stroke and fine-stroke descriptions of desirable educational materials that provide directions for developing them.
Interaction of geotechnics with society through education
Authors: Mascarenha Márcia , Camapum de Carvalho José , Jesus Andrelisa , Rezende Lilian , Sales Mauricio , Luz Marta
Published: October 2023

The Federal University of Goiás (UFG) and the University of Brasília (UnB), in partnership with the company Eletrobras Furnas, have developed research and, based on this, extension projects aimed at education in a broad sense, in which they seek to disseminate and popularise technical-scientific knowledge. This paper aims to present and evaluate educational actions carried out in the area of soil science and geotechnics applied to engineering, geography, and the environment. To do so, the educational experiences developed within the scope of two extension projects are shared. Beside that, the relevance of publishing books and primer, with language adapted to lay society, within the scope of research projects, is analyzed. The results collected regarding the effectiveness of the extension actions as a tool for learning point to a positive evaluation by the students. Furthermore, social networks are an important tool for scientific dissemination and have the potential to disseminate knowledge more widely than in a classroom course. By comparing the number of citations in Google Scholar of the books and booklets with the papers arising from these projects, one can observe the reach of this type of publication, although its purpose is the popularisation of science, with reach in places not considered in the technical-scientific publication metrics. Finally, for effective scientific development, it is necessary to have public policies, effective interaction between universities, research centres and schools, and the participation of professional associations, funding and evaluation agencies, Education Departments and the Ministry of Education, Science, Technology and Innovation.