bluuebunny/crossref_metadata_2025 huggingface dataset:
ENHANCING BLACK COTTON SOIL WITH POLYPROPYLENE FIBER REINFORCEMENT: A GEOTECHNICAL APPROACH
Authors: Pratap Akshaya , Kumar Rajendra
Published: June 2024

Black cotton soil, also known as expansive clay soil, is a type of highly expansive and shrinkable soil that poses significant engineering challenges for construction projects. The expansive nature of this soil can lead to significant differential settlements and structural damage in buildings and infrastructure. This chapter aims to explore the potential of using polypropylene fiber as a stabilizing agent to enhance the geotechnical properties of black cotton soil. The research investigates the effects of incorporating polypropylene fiber on key soil parameters, such as strength, shrinkage, and swelling characteristics. The findings from this study could offer valuable insights into sustainable and cost-effective methods for mitigating the adverse effects of black cotton soil in construction and geotechnical applications.
HYDROGEL DRESSING FOR WOUND HEALING
Authors: Kumari Monika
Published: June 2024

Wound healing technologies have witnessed a transformative shift with the advent of 3D printed hydrogels. This chapter explores the unique advantages offered by 3D printed hydrogels over traditional counterparts. By harnessing the power of additive manufacturing, these hydrogels allow for unparalleled customization and complexity in design, offering precise control over shape and architecture. The spatial control of bioactive agents within these hydrogels enables targeted and localized delivery of therapeutic compounds, enhancing their efficacy in wound healing applications. Moreover, the improved mechanical strength and stability of 3D printed hydrogels, achieved through innovative internal architectures, make them robust and adaptable for diverse clinical scenarios. Their patient-specific fit ensures optimal wound coverage and contact, while their multi-functionality, incorporating various components within a single structure, enhances their therapeutic potential. Additionally, the rapid prototyping and scalability of 3D printed hydrogels have revolutionized the speed and efficiency of production, paving the way for widespread clinical adoption. Although challenges such as biocompatibility and long-term stability persist, the evolution of 3D printed hydrogels represents a promising frontier in advancing wound care and tissue engineering, heralding a new era in medical innovation and patient-specific treatments.
SYNTHESIS AND CHARACTERIZATION OF METAL OXIDE NANOPARTICLES: APPROACHES AND TECHNIQUES
Authors: S. Kamble Vishal , S. Kamble Satyajit , L. Khairnar Sagar , K. Patil Digambar , S. Ghadge Sushil , K. Desai Netaji , N. Patil Rahul , M. Pawara Jitendra
Published: June 2024

The abstract provides a succinct summary of a wide array of techniques used in the synthesis of metal oxide nanoparticles. It places particular emphasis on two primary approaches: "top-down" and "bottom-up" methods. These techniques encompass a diverse range of environments, including gases, liquids, solids, supercritical fluids, and vacuum conditions.In the "top-down" approach, the focus lies on breaking down bulk materials into nanoparticles. On the other hand, the "bottom-up" approach involves the assembly of atoms or molecules into nanoparticles, often with the assistance of stabilizers. Within this context, the abstract explores commonly employed methods such as chemical vapor deposition, sol-gel, and co-precipitation. Each of these methods is analyzed with its respective advantages and disadvantages in mind.To gain a deeper understanding of the structural and optical properties of these nanoparticles, various characterization techniques are discussed, including X-ray diffraction (XRD), field-emission scanning electron microscopy (FESEM), high-resolution transmission electron microscopy (HRTEM), Fourier-transform infrared spectroscopy (FTIR), UV-visible spectroscopy (UV-VISIBLE), energy-dispersive X-ray spectroscopy (EDAX), and X-ray photoelectron spectroscopy (XPS).In summation, this abstract offers a concise yet comprehensive overview of the preparation and characterization methods employed in the realm of metal oxide nanoparticles.
PROGRESSIVE ATTRIBUTES OF INTERNET OF NANO-THINGS (IONT)
Authors: Neogi Debolina , Basu Debalina , Banerjee Ananya , Mitra Riddhi , Soumik Podder Dr.
Published: June 2024

Numerous advances have been created during the life span of human beings and utilized to progress every individual’s life. These breakthroughs will proceed to influence the longer term of mankind. Such innovations have molded who we are presently and are display in each zone fundamental for human survival, counting transportation, healthcare, and farming. Since its conception, nanotechnology has advertised progressed and viable arrangements for a few healthcare, mechanical, rural, and military employments. Nanotechnology has started the progress of infinitesimal components called Nano-machines, which are made up of requested bunches of particles and accomplish foreordained capacities. The "Internet of Nano Things" (IoNT) standard was developed as a result of the interfacing of Nano sensors and Nano gadgets with the Web. The essential objective of this work is to grant a comprehensive outline of the Internet of Nano Things (IoNT)—its design, application spaces, and challenges in arranges to teach scholastics approximately the IoNT standard and empower them to receive it in an assortment of areas within the close future for fast arrangement whereas overcoming current impediments.
BIOSYNTHESIS AND CHARACTERIZATION OF ENCAPSULATED CHITOSAN-IRON OXIDE (FE3O4) HYBRID NANOCOMPOSITE BEADS – ITS DUAL POTENTIAL AS FERTILIZER FOR VIGNA RADIATA AND PESTICIDE AGAINST MELOIDOGYNE INCOGNITA
Authors: Alphonsa Juliet Helina JK.
Published: June 2024

In virtue of the advanced characteristics of the chitosan derived iron oxide nanocomposites (Fe3O4) fascinated the attentions in diverse applications owing to their exclusive physico-chemical properties. Additionally, owed to their exceptional surface area, compatible size in nanoscale, spherical shape and ecological synthesis pathway make them preferable and sensible in industrial, agricultural and pharmacological area of research. Based on this scrutiny, it aims to the bio-synthesis of chitosan derived iron oxide nanocomposites (Ch-Fe3O4) hybrid beads. The reports expose that the nanocomposite hybrid beads have effective agricultural applications as fertilizer for Vigna radiate and pesticide against Meloidogyne incognita. Exceedingly cost-effective and environmentally benign methodology ropes the fabrication (Ch-Fe3O4) nanocomposites in high yield. The SEM image reveals that, the chitosan-iron nanocomposites possess spherical shape and the size of 81.7nm. The resultant Fe-O band at 551.86 cm-1 indicates the formation of the nanocomposites. The EDX signals for iron and oxygen atoms only obtained supplementary confirms the formation of nanocomposites. The absorbance peak at 395.05nm in UV-Visible spectrum evidently proves the synthesis of (Ch-Fe3O4) nanocomposites. The synthesized (Ch-Fe3O4) nanocomposites were encapsulated and converted to hybrid beads. The (Ch-Fe3O4) nanocomposites hybrid beads effectively acts as a good fertilizer which enhances the growth of Vigna radiate seeds. The (Ch-Fe3O4) nanocomposites hybrid beads as pesticide extremely disrupts the growth of Meloidogyne incognita isolated from the root of the Musa acuminata.
TEACHING ORIENTALISM IN AN UNDERGRADUATE CLASSROOM
Authors: Pathan Dr. Sufiya
Published: June 2024

Orientalism’ has become an important concept to grapple with in domains like Literature, History, Sociology and Cultural Studies, to name just a few. Said’s book by the same name is the main text that needs to be introduced to students when dealing with this idea. However, Said’s work makes its case using texts that are far from familiar to students even of Literature, to say nothing of other fields. Therefore, it can be quite challenging to introduce the concept convincingly to students in an Indian under-graduate classroom. This essay takes up this pedagogical challenge by introducing Said’s key ideas by demonstrating them through the use of a popular and accessible 21st century text, the film 300, and its important precedents in print and visual culture. The essay can be a guide for teachers or even a starting point for students to use in the classroom to understand the concept of orientalism in simple and accessible terms.
FADING LILIES IN THE BARTER SYSTEM: REVIEWING EDITH WHARTON’S THE HOUSE OF MIRTH FROM A FINANCIAL LENS
Authors: Roy Ghatak Dr. Manonita Chowdhary
Published: June 2024

Edith Wharton’s preoccupation with the theme of money and its consequent class conflict led her to view the society as an economist where courtship, mating, and marriage are nothing more than voluntary transactions conducted in a market-like atmosphere. Various authors have produced multiple theories on Edith Wharton’s use of economic concepts in The House of Mirth. Apart from viewing the novel from a Marxist perspective and applying neoclassical economic theories to the novel what makes it a substantial reading in the modern context is that various modern economic theories can also be applied to it and the present paper is an attempt towards that. It seeks to view the novel through the close lens of present-day theories of Finance and Economics, to be specific, the basic theory of Behavioral Finance. In the present paper, Lily’s dilemma and her equivocal purpose to choose between a wealthy life with a person of high social rank or to live a life of poverty with her moral righteousness have been reviewed through the perspective of Behavioral Finance. It offers a useful yardstick through which Lily’s dual attitude towards money, her dream of a happy and wealthy life, and her notion of happiness can be analyzed.
RECENT ADVANCES IN THERAPEUTIC ORAL MEDICINE
Authors: Ayesha Dr. Humera
Published: June 2024

Oral mucosal lesions which are treated in Oral Medicine department includes, Recurrent Aphthous Stomatitis, Allergic stomatitis, Lichen Planus, Pemphigus, Pemphigoid, OSMF, Leucoplakia, Erythema Multiforme, Herpes Simplex Viral Infections, Herpes Zoster viral infection. There are various treatment modalities available in this literature. This chapter aims to review only the recent advancement in therapeutic Oral Medicine in the management of oral mucosal lesions which are enlisted below. Crocin delivery system through Thiolated chitosan hydrogel-embedded niosomes Amlexanox-loaded nanoliposomes in oral mucosal lesions. Management of oral mucosal lesions with montelukast. Anti-TNFα F(ab) delivered through electrospun patch for the management of inflammatory oral mucosal diseases. Topical calcineurin inhibitors (TCI). Kinase inhibitors. Topical 5-fluorouracil be used as a viable treatment option for oral premalignant lesions and tumors. Diethylcarbamazine, an anti-filarial medication, is used to treat oral submucous fibrosis. Molecular targeted therapies. ICI-based therapies Immunotherapy for malignancies of the keratinocytes. Section II: Determination and treatment of cutaneous immunotherapy adverse effects Botulinum toxin in the management of head and neck disorders Trends in orally viral vector gene delivery and therapy A novel approach to the oral delivery of bionanostructures for systemic disease Oral administration of therapeutic proteins that are plant cell-encapsulated
ROBOTICS IN SURGERY AND HEALTH CARE
Authors: Khatoon Dr Fatima , Banu Summaiya , Kazim Dr Syed Mohammed , Aleem Dr M A , Fatima Dr Nabeela
Published: June 2024

The use of robots in surgery and healthcare has brought about a paradigm change that is revolutionizing how patients are treated and medical operations are carried out. Simple tele manipulators gave way to complex, autonomous platforms as robotic technologies in surgery advanced. They provide unmatched dexterity, precision, and the capacity to carry out minimally invasive treatments with improved visualization. Now, difficult surgeries may be carried out by surgeons with fewer incisions, less blood loss, and quicker patient recoveries. Robotic surgery is used in a variety of surgical specialties, including general surgery, urology, gynecology, and orthopedics. Robots are being used in the healthcare industry for patient care, rehabilitation, and medical logistics in addition to surgery. Robots used in telemedicine make it possible to monitor and consult on patients from a distance, enhancing access to healthcare services, particularly in underdeveloped regions. Robotic exoskeletons and other assistive technology improve the quality of life for those with mobility limitations by helping with physical therapy and rehabilitation. Autonomous delivery robots also streamline the supply chain, guaranteeing prompt distribution of medical goods and lightening the load on medical staff. Robotics use in healthcare is not without difficulties, though. Regulation barriers, high start-up costs, and worries about employment displacement must all be addressed. Additionally, it is important to carefully address the ethical implications of robots in healthcare, including responsibility and data privacy. In conclusion, the use of robots in healthcare and surgery is a revolutionary development. Although there are still issues, the advantages in terms of better patient outcomes, increased effectiveness, and more access to healthcare services are indisputable. Robotics integration is positioned to become more and more important in determining the future of patient care and healthcare delivery as technology develops.
ADVANCES IN CAR-T CELL THERAPY: A PROMISING TREATMENT MODALITY
Authors: Ingawale Dr Sushrut , Darooka Dr Naitica , Paras Dr
Published: June 2024

This chapter provides a comprehensive exploration of the evolution and significance of chimeric antigen receptor (CAR)-T cell therapy in cancer treatment. Beginning with an overview of CAR-T therapy's historical development and its profound impact, the chapter delves into its core principles, including CAR structure, genetic engineering, and mechanisms of action. The clinical successes of FDA-approved therapies in hematological malignancies are examined, along with considerations for expanding into solid tumors. The chapter discusses target antigen selection, engineering strategies, overcoming tumor microenvironment challenges, and safety management, addressing cytokine release syndrome and neurological toxicities. Next-generation CAR-T therapies, manufacturing complexities, commercialization challenges, global access, future directions, emerging technologies, and ethical considerations are all analyzed. Ultimately, the chapter offers a comprehensive understanding of CAR-T cell therapy's potential, challenges, and transformative impact on cancer treatment.
A COMPREHENSIVE REVIEW OF EXPERT SYSTEMS IN PROFESSIONAL EDUCATION: CURRENT TRENDS AND FUTURE DIRECTIONS
Authors: Patil Dr. Smita Pradip , Patil Mrs. Sonali Shinde
Published: June 2024

Expert systems, an inventive branch of artificial intelligence, have gained awareness in the field of professional education due to their prospective to enhance learning outcomes & decision-making processes. This research paper aims to provide a comprehensive review of expert systems into professional education, focusing on current trends and future directions. Through an analysis of recent literature and research studies, we explore the applications, benefits, challenges, and emerging trends of expert systems within the context of professional education. The findings of this review shed light on the present state of expert systems into professional education and offer insight into their potential for future advancements. Furthermore, the papers do ahead future advancements had driven by expert system and data, emphasizing potential benefits for learner engagement and lifelong learning. This research offers valuable insights for educators and policymakers into the current landscape and future opportunities of expert systems in professional education.
FORM FILLING MODULE OF ONLINE APPLICATION MANAGEMENT SYSTEM IN MICRO SERVICE ARCHITECTURE
Authors: Naik Dr. P.G. , Shinde Dr. Ajay D. , Thorat Mr. R.T.
Published: June 2024

COVID-19 pandemic terribly affected virtually all the sections. Among them the education sector was the most affected. To restore back the smooth functioning of academics it was inevitable to shift all the tasks to online mode. The functioning of any education system starts with admission process. When the tasks are conducted remotely in online mode many new challenges automatically creep in which need to be addressed in order to ensure that virtual platform offers the same security and reliability as its offline counterpart. Few security challenges that need to be addressed are authenticity, integrity, confidentiality and non-repudiation. Further when the application is hosted in online mode, the additional software testing techniques pertaining to load testing, proactive measures for unexpected network traffic, concurrency control mechanisms, transaction control mechanisms, security testing need to be performed. In the current research, the authors have designed and developed an online application module. The current work focuses on form filling module which is crucial part of the application. The conceptual design focusing on data persistence, module dependency, business rules employed in the middle tier of scalable N-Tier architecture, workflow, module functionalities and module executions are dealt with at depth.
EXPLORING DATA MINING TRENDS AND RESEARCH FOCUS IN INDIA (2018-2022): A COMPREHENSIVE BIBLIOMETRIC ANALYSIS
Authors: Esh Manash
Published: June 2024

This study comprehensively analyses “Data Mining” research in India from 2018 to 2022. The study utilises data from Scopus and employs R programming with the R-Studio package and Biblioshiny for data analysis. 5211 articles were analysed, and missing data were handled through imputation or removal. The research focuses on articles only and includes basic summary statistics to understand the dataset's characteristics. Applying Bradford's Law confirms its accuracy with an R-squared value of 0.972. The lattice plot of CiteScore publications from 2011 to 2019 shows temporal variations, indicating fluctuating impact for different journals. The grouped bar chart illustrates document distribution among affiliations, emphasising the leading contributors. Funding sponsor analysis highlights the significance of different sponsors in supporting research articles. The study offers meaningful interpretations and addresses research questions related to data mining in India. The results contribute to understanding data mining's impact and trends in the Indian context.
BIG DATA AND BIG DATA ANALYTICS
Authors: Agrawal Jaishree , Nautiyal Kapish
Published: June 2024

Big Data and Big Data Analytics are terms used to describe the enormous amount of information that is produced daily in our contemporary digital environment. The term "big data" refers to massive, complex data volumes that are very challenging to handle and manage successfully when using traditional data processing methods. These data come from a wide range of sources, such as social media, sensors, online transactions, and more. On the other hand, big data analytics is the process of investigating and understanding these enormous databases in order to uncover crucial data, patterns, and trends. People use specialized tools and procedures to make sense of the data and turn it into knowledge that can be used to make better decisions and take the right actions. In this abstract, it is discussed how significant Big Data and Big Data Analytics are in modern culture. We talk about how businesses, governments, and organizations use these technologies to make wise decisions, deliver better services, and boost productivity. Big data analytics has several benefits, including a greater understanding of customer preferences, the identification of potential risks, and the prediction of future trends. Additionally, we go through issues with big data management, such as data privacy, security, and the need for sophisticated computing resources. The ethical concerns surrounding the use of big data are also underlined, with an emphasis on the need for responsible data usage to safeguard individuals' privacy and maintain confidence.
MULTIPLE ENCRYPTION TECHNIQUES IN CLOUD COMPUTING: ENHANCING DATA SECURITY AND PRIVACY
Authors: S Jeevakumar , D. C Christo Melbin
Published: June 2024

Cloud computing has brought about a revolutionary transformation in how organizations handle data storage, processing, and management. However, the shift to cloud-based services has raised concerns about data security and privacy. As cloud environments are inherently prone to cyber threats and unauthorized access, employing strong encryption methods has become crucial to safeguard sensitive information. This paper explores the concept of multiple encryption techniques in cloud computing, their advantages, challenges, and the potential impact on data security and privacy.
ARTIFICIAL INTELLIGENCE IN CLINICAL TRIALS
Authors: Gupta Dr. Sonu , Garg Dr. Ruchika , Bansal Dr. Ravinder Nath , Bansal Dr. Sanjana
Published: June 2024

In the era of evidence based medicine thousands of clinical trials are conducted generating huge data from trial participants. Traditional trials highlighted ethical issues leading to patient withdrawal from trials, inadequate enrolments which gave rise to digitalisation with intent to promote authenticity, integrity in clinical research. Artificial intelligence (AI) is a boon in digitalization. It strengthened patient- physician relationships but it also contained some negative aspects which are being resolved. AI creates strong framework for clinical data management.
EVIDENCE-BASED PRACTICE IN NURSING PROFESSION
Authors: Garg Dr. Ruchika , Bansal Dr. Nitin
Published: June 2024

Evidence based medicine (EBM) is very much recognized and practiced since past 10 years. EBM is a multi-integrative approach involving opinions from patients, their family and caregivers. Nurses can improve their knowledge and clinical experience from available resources and implement them as and when required. Evidence-based practice (EBP) mainly focuses on the patient which is the heart of nursing care. EBP influences the proficiency skills and work responsibilities of nurses so it should be integrated into routine health care practices. There may be necessary healthcare environment for organizations in evidence-based practice supporting it. EBP has its own limitations and benefits. Regarding the implementation of EBP guidelines majority of healthcare practitioners and organizations are still lacking behind for the sake of providing best health care. These identified barriers can be overcome by facilitating the implementation of evidence-based practice among healthcare professionals with the help of Nursing administrators and educators. Training and education must be provided to them to enhance knowledge, skills and awareness to utilize EBP. Provision of adequate resources, time management and guidance can help in facilitation of EBP for better health care.
GREEN SOLVENTS: AN APPROACH TOWARDS SUSTAINABLE DEVELOPMENT
Authors: Bhandari Divya Dhawal , Kaur Tejinder , Joshi Gaurav , Kondal Neha
Published: June 2024

Presently, organic synthetic chemistry is the one major part of science which is using various solvents among which few are toxic and carcinogenic. In synthetic reactions, the use of protective equipment such as goggles, breathing apparatus, face-guard masks can reduce the exposure to harmful chemicals in daily life. The biggest threat is organic solvents which are used in all chemical reactions and mostly released in environment as volatile organic compounds (VOCs) due to leakage. This is because the VOC’s are more in any reaction than reagents and side products. So the main problem lies to either remove solvents completely or by substituting VOCs with cheap technological medium which is not harmful for the health of humans and the environment. Also, the main industrial waste is solvents only but, if we choose carefully, the usage and type of solvent, then we can eliminate waste production and can increase reaction output. As indicated by green chemistry principles, use of safer raw material and eco-friendly solvents can eliminate the risk of a production process. So, the present topic is mainly on the use of such carefully selected solvents which are eco-friendly so better known as green solvents: an approach towards green chemistry.
NUCLEAR MEDICINE
Authors: Lata Dr. Suman , Kaur Hardeep , Gagandeep Mr.
Published: June 2024

Nuclear medicine is a branch of medicine that uses radioactive substances in extremely small quantities to diagnose and treat a variety of conditions, such as heart and blood vessel problems, some malignancies, and neurological disorders. Nuclear medicine (NM) has witnessed both evolutionary and revolutionary advances during the past several decades. The introduction of advanced imaging systems with quantification capabilities, such as single-photon emission computed tomography/computed tomography [PET]/CT, positron emission tomography [PET]/CT, and PET/magnetic resonance, as well as the dynamic and responsive trends in the global development and use of radiopharmaceuticals (RPh), are major contributors to this.
ADVANCES IN MICROENCAPSULATION: FROM TECHNIQUES TO APPLICATIONS
Authors: G Subasri. , S Ram Kumar. , Gayathri H.
Published: June 2024

Microencapsulation is a versatile and innovative technology with applications spanning various fields, including pharmaceuticals, food, cosmetics, agriculture, and more. This process involves encapsulating tiny particles or droplets within a protective shell, resulting in improved stability, controlled release, and enhanced functionality of the encapsulated materials. The encapsulation techniques can be classified into different categories such as spray drying, coacervation, emulsion-based methods, and layer-by-layer assembly. This abstract provides an overview of microencapsulation principles, methods, and their widespread applications. It highlights the significance of microencapsulation in extending product shelf-life, protecting sensitive ingredients, controlling release kinetics, and enabling targeted delivery. The choice of encapsulation material, core material, and encapsulation method greatly influences the final properties and performance of microcapsules. As research in microencapsulation continues to advance, the potential for designing novel formulations and optimizing encapsulation processes becomes increasingly promising. This abstract underlines the importance of microencapsulation as a tool for innovation in various industries and its role in shaping the future of functional materials and product design.
NUCLEAR MEDCINE
Authors: R Sirangevi , A Ramakrishnan
Published: June 2024

Nuclear medicine is an integrative field encompassing nuclear physics, chemistry, and medicine, utilizing radioactive materials (radiopharmaceuticals) for disease diagnosis and treatment. It provides both anatomical and functional information simultaneously, aiding in early disease detection and treatment planning. The principles of nuclear medicine involve the use of various radiopharmaceuticals, including Technetium-99m (Tc-99m), Fluorine-18 (F-18), Iodine-131 (I-131), and Gallium-67 (Ga-67), targeting specific organs or tissues for diagnostic and therapeutic purposes. Imaging techniques such as Single-Photon Emission Computed Tomography (SPECT), Positron Emission Tomography (PET), Planar Scintigraphy, and Hybrid Imaging play key roles in visualizing physiological processes. Pharmacists are integral in radiopharmaceutical preparation, quality control, dispensing, and radiation safety, ensuring compliance with regulatory standards. Nurses support patient education, preparation, monitoring, and post-procedure care, contributing to comprehensive patient management. Collaboration between pharmacists and nurses optimizes nuclear medicine's diagnostic and therapeutic benefits, emphasizing patient safety and effective healthcare delivery. This integrated approach underscores the significance of nuclear medicine in modern medical practice.
CHALLENGES AND BARRIERS TO THE IMPLEMENTATION OF FUTURISTIC PHARMACY TRENDS
Authors: Sah Dr. Roshan
Published: June 2024

The integration of artificial intelligence (AI) and machine learning (ML) in the field of drug discovery and development has ushered in a transformative era. These technologies leverage vast datasets, including genomic information, chemical properties, and clinical trial outcomes, to accelerate the identification of potential drug candidates. AI algorithms analyze complex biological interactions, predict drug-target interactions, and optimize molecular structures, expediting the traditionally time-consuming drug discovery process. Additionally, ML models enhance personalized medicine by tailoring treatments based on individual patient characteristics. This synergy of AI and ML not only accelerates drug development but also holds the promise of delivering more precise and effective therapies, marking a revolutionary paradigm shift in the pharmaceutical industry.
FINANCIAL RISK MANAGEMENT AND DERIVATIVES
Authors: Joshi Pratham
Published: June 2024

Financial Risk Management Involves understanding & managing the financial risks faced by the organisation it alludes to the most common way of recognizing, surveying, and overseeing potential dangers and risks that can impact an association's financial well-being. It involves the implementation of strategies and practices to mitigate or minimize the negative consequences of these risks, while maximizing opportunities for growth and profitability. The significance of financial risk management lies in its ability to protect an organization from unexpected events or circumstances that can jeopardize its financial stability and viability. By proactively identifying and addressing risks, organizations can safeguard their assets, optimize their financial performance, and maintain investor confidence. Effective risk management enables businesses to make informed decisions, allocate resources efficiently, and navigate through uncertain economic conditions.
AN IMPACT OF ARTIFICAL INTELLIGENCE ON FINANCIAL DECISION MAKING
Authors: K.A Karthick Srivatchan. , S.G Srimathi. , K.S Vaishnavi. , S Sowmiya.
Published: June 2024

This study explores how artificial intelligence (AI) has significantly changed how people make financial decisions. AI technology integration into the financial industry has resulted in revolutionary developments as it continues to develop at an unheard-of rate. The traditional paradigms of risk assessment, investing approaches, and market forecasting are examined in this study in the context of AI-driven algorithms, machine learning models, and predictive analytics. We clarify the potential and problems given by AI in financial decision making by examining real-world case studies and market trends. The ethical issues and legal frameworks regulating AI's application in finance are also examined. This research adds to a thorough knowledge of the shifting dynamics inside financial decision making in a world that is increasingly driven by AI through an in-depth investigation of the influence of AI.
THE PARADOXICAL IMPACTS OF ELECTRONIC PERFORMANCE MONITORING AND ITS SOLUTIONS
Authors: Palayoor Alex Joy , D Mavoothu Dr.
Published: June 2024

Due to the current landscape characterized by swift advancements in information technology and the resultant surge in communication, a diverse array of approaches and techniques are employed for overseeing employees in their professional roles. Employers primarily emphasize the utilitarian facets of workplace surveillance, such as heightened efficiency, workplace and operational safety, and overall quality. Conversely, critics of such monitoring underscore its ethical implications, focusing on the violation of employee privacy, which can consequently lead to a decline in mental and physical well-being, originality, independence, and overall effectiveness. In this context, both the utilitarian and ethical dimensions of electronic performance monitoring are thoroughly deliberated. To strike a harmonious balance, strategies involving constructive feedback, prior notification of electronic performance monitoring protocols, involvement of employees in the formulation and execution of monitoring systems, and due regard for the employee perspective on surveillance are explored as mutually beneficial resolutions.
"HARNESSING ARTIFICIAL INTELLIGENCE (AI) AND AUTOMATION FOR ENHANCED DECISION-MAKING IN MANAGEMENT"
Authors: Kumari Priyanka
Published: June 2024

The rapidly evolving landscape of technology has paved the way for groundbreaking advancements in the field of artificial intelligence (AI) and automation. These technologies hold immense potential to revolutionize management practices across various industries. This study aims to explore the integration of AI and automation in management decision-making processes and the potential benefits and challenges it presents. Research Objectives: • To investigate the current state of AI and automation in management and identify the emerging trends and applications. • To understand the impact of AI-driven decision support systems on management decision-making processes. • To examine the potential benefits of AI and automation, including increased efficiency, accuracy, and predictive capabilities in decision-making. • To identify the challenges and ethical considerations associated with the adoption of AI and automation in management. • To propose practical strategies for organizations to harness the potential of AI and automation while addressing associated challenges. As AI and automation become increasingly prevalent in the business landscape, understanding their implications for management decision-making is of paramount importance. This research can equip managers and leaders with insights to make informed decisions about integrating AI-driven solutions in their organizations. Furthermore, it can shed light on how AI and automation can complement human expertise, leading to more efficient and effective decision-making processes. This study will focus on various industries where AI and automation are increasingly being implemented for management purposes. It will cover decision-making processes across different management domains, such as finance, operations, marketing, and human resources. The research will include case studies and interviews with professionals to gain a comprehensive understanding of the impact of AI and automation in real-world scenarios.
AGRICULTURE-RELATED RECENT TRENDS IN MACHINE LEARNING APPLICATIONS: A COMPLETE ANALYSIS
Authors: Rathore Megha , Sharma Piyush , Chouhan Rajni Kumari , Lavania Krishan Kant
Published: June 2024

As the world population continues to grow, the agriculture industry faces the daunting task of producing more food with limited resources and in an environmentally sustainable manner. In recent years, the integration of machine learning techniques into various agricultural processes has gained significant attention due to its potential to revolutionize the sector. This review paper provides an extensive analysis of the current trends and advancements in the use of machine learning in agriculture, focusing on key applications, challenges, and opportunities. We examine a diverse range of research articles, case studies, and projects to present a comprehensive overview of the field and its implications for the future of agriculture.
REGULATION OF MOBILE USAGE
Authors: Akhil Pandey Dr. , Vishal Shrivastava Dr. , Sangeeta Sharma Er.
Published: June 2024

This research paper examines the regulation of mobile phone utilization and its effect on society. With the expansion of mobile phones and their far and wide use, concerns have emerged in regards to their expected adverse consequences on human wellbeing, social connections, and efficiency. The paper surveys the current examination on the effect of mobile phone utilization, incorporating the dangers related with exorbitant use and fixation, and the likely advantages of managing mobile phone use. The degree of virtual entertainment dependence isn't that serious with just slight habit recognized. There is a huge positive relationship between virtual entertainment enslavement and psychological wellness, explicitly loss of focus, despondency, and tension, in that grouping. In general the review proposes that to stay away from psychological wellness issues (sadness, nervousness, and loss of focus), understudies ought to restrict their experience via virtual entertainment and lower their reliance propensity on them. This research paper gives experiences into the present status of guideline of mobile phone utilization and gives proposals for future arrangement advancement to advance mindful and sound mobile phone use.
ARTICLE ON VAGUS NERVE STIMULATION
Authors: Priyanka Gujar Ms. , Deepali Tayde Ms. , Kajal Motghare Ms. , Patricia Reddy Ms.
Published: June 2024

Introduction: The vagus nerve, often known as the "vagary," is engaged in a variety of activities throughout the body. Vagus Nerve Stimulation (VNS) has the potential to influence many of these functions. The US Food and Drug Administration (FDA) has approved clinical applications of VNS Therapy, as well as information regarding ongoing trials and preclinical research to broaden the use of VNS to new applications. VNS is currently licensed by the FDA for therapeutic use in patients over the age of 12 with drug-resistant epilepsy and depression. This broad capability has sparked considerable interest across a variety of fields, culminating in a number of clinical trials and studies into the foundation of Vagus Nerve Stimulation. Conclusion: Vagus Nerve Stimulation is an effective therapy that has previously been approved by the FDA for the treatment of seizures. Preclinical and clinical experiments have revealed a possible benefit in a growing number of diseases. Finally, otogenetics has significant promise for assisting mechanistic studies of VNS.
EMERGENCE OF PHYTOSOMES IN THE FIELD OF NOVEL DRUG DELIVERY SYSTEM
Authors: Ganguly Shayeri Chatterjee , Das Aliviya , Sangram Sk , Bhattacharya Disha , Paul Sayani
Published: June 2024

In the arena of novel drug delivery system, phytosomes have emerged as a ground-breaking carrier system, owing to elimination of side effects, that are generally caused in case of metallic nanocarriers or those having synthetic origin. Phytoconstituents have been stated to have strong in vitro pharmacological activity, although possessing poor in vivo absorption. In order to increase their bioavailability and absorption, combatting the drawbacks and undesirable effects of traditional herbal extracts, among various novel drug delivery systems. Phytosomes resolves the problem of low bioavailability, apart from target specific conveyance of drug, it also reduces adverse effects, amends absorption, lowers dose and augments therapeutic efficacy. Many researchers have reported the pharmacological potential of phytosomes and established its supremacy, on comparison to the efficacy of traditional drugs as well as conventional liposomes.Phytosomes are well-known biocompatible nanocarriers that can be employed to increase the solubility and permeability of phytopharmaceuticals. This review aims to provide a comprehensive insight about the characteristics, method of fabrication, application in drug delivery and therapeutics, with the challenges faced and the future prospects of phytosomes.
MULTIDISCIPLINARY APPROACHES FOR TREATING RHEUMATOID ARTHRITIS
Authors: Pratibha Rahul Adnaik Mrs. , Rahul Shivaji Adnaik Dr.
Published: June 2024

Variable levels of joint deterioration are present in people with rheumatoid arthritis (RA), a chronic, inflammatory, and systemic autoimmune disease. One percent to two percent of persons between the ages of 20 and 50 globally suffer from this severe joint condition. Age, genetics, gender, and environmental factors like smoking, exposure to pollution, and employment are all chance factors. Since there is no recognised treatment for RA, the goals of treatment are to lessen pain and prevent further damage. TNF-blockade, B cell therapy, IL-1 and IL-6 blockade, among other things, are treatments for RA. Modern disease-modifying antirheumatic drugs (DMARDs) and other therapeutic modalities have changed how rheumatoid arthritis (RA) is managed, favouring more sophisticated, aggressive therapies. The ultimate goal is to stop structural joint degradation, which results in pain and functional impairment. Early DMARD treatment in conjunction with nonsteroidal anti-inflammatory drug tablets is recommended for RA, which must be detected early. Combination DMARD regimens and novel biologic drugs (interleukin [IL]-1 antagonist and anti-tumor necrosis factor [TNF] treatments) have drawn interest as potential choices for the early treatment of RA patients. These new biologic marketers and incoming nonbiologic vendors that concentrate on proteins in signalling cascades will likely transform the market for RA treatments. In spite of this, between 60 and 90 percent of arthritis sufferers take traditional medication. The effectiveness and safety of such conventional medications must be improved as a result. RA is managed using a comprehensive interdisciplinary approach to reduce pain and infection while restoring joint function. It is preferred to treat rheumatoid arthritis thoroughly. Rheumatologists, rehabilitation specialists, occupational therapists, physical therapists, social workers, nurses, guide therapists, podiatrists, dieticians, psychologists, career counsellors, and orthopaedic surgeons have collaborated to develop a patient-focused fitness care model that is effective on all levels.
PRODRUG: APPROACH TO BETTER DRUG DELIVERY
Authors: Gavhane Snehal A. , Somwanshi Sachin B.
Published: June 2024

Albert was the first to introduce the idea of a prodrug in medicinal chemistry. "A prodrug is a molecule that lacks intrinsic biological activity but can produce a biologically active drug through the various stages of its metabolism," according to the definition provided. This definition and the one adopted by IUPAC both state that a prodrug is any substance that goes through biotransformation prior to manifesting its pharmacological effects. Prodrugs can be thought of as medications that temporarily alter or remove undesired qualities in the parent molecule by adding specialised non-toxic protecting groups. In order to be effective, a prodrug must be able to solve a crucial paradox: while it must be hydrophilic enough to satisfy solubility, bioavailability, and transport requirements, it must also be lipophilic enough to cross a membrane or metabolic barrier. An appealing substitute is a chemical remedy that uses a prodrug strategy. By modifying physico-chemical factors that affect absorption or by focusing on certain enzymes or membrane transporters, the prodrug method has also been frequently employed to enhance drug delivery to its site of action. With this in mind, a prodrug design is a lead modification technique used to fix a flaw in a drug candidate. It may be helpful in avoiding issues with formulation and solubility, absorption and distribution, instability, site specificity of liberation, prolonged release, and toxicity, among other effects.
PRODRUG: A BRIEF CONCEPT
Authors: Sahu Swapna , Singh Kiran , Verma Prashant Kumar , Chaurasiya Sudhakar
Published: June 2024

Prodrugs are the pharmacologically inactive forms of the active substances of a drug. The active substance undergoes chemical and / or enzymatic biological transformation to release the relevant active drug. The resulting conversion product (the parent drug) then provides the pharmacological response required. Since synthesizing new compounds is time-consuming and expensive, developing derivatives of existing drugs is certainly an exciting and promising field of research. High attrition in drug development is largely due to pharmacokinetic and pharmaceutical issues. Prodrug design addresses these issues effectively. Poorly permeable drugs are lipophilic, which can be improved by connecting the drug with a lipophilic drug linker. This allows the drug to be delivered orally, ocularly or locally. In addition, prodrugs can bind to polar or ionizing groups to enhance water solubility. Site selectivity is achieved by targeting specific enzymes or receptors.
MYCOREMEDIATION OF SYNTHETIC DYES: A REVIEW
Authors: Kharat Kalpana Sudam
Published: June 2024

Wastewater containing dyes, originating from industries like textiles, poses a grave environmental threat. Detoxifying these hazardous dyes is essential for environmental compliance. While physicochemical methods exist for dye removal, the harmful potential of chemical breakdown by products is a concern. The review delves into the intricate biochemical processes involved in mycoremediation, highlighting the role of fungal species (enzymes) in the degradation of complex dye molecules. The sustainability and versatility of mycoremediation are explored, alongside limitations like fungal specificity and potential slower kinetics. In conclusion, this chapter underscores mycoremediation's promise as an eco-friendly solution, emphasizing the need for further research and interdisciplinary collaboration to optimize its efficacy in environmental restoration.
TRANSGENICS: AN OVERVIEW
Authors: V Vismaya , M Devasurya , R Priya , Sundarapandian Mahalakshmi
Published: June 2024

Transgenics, also known as genetic engineering or modification, is a field of biotechnology that involves manipulating the genetic material of an organism to introduce desired traits from another organism. This process commonly involves transferring genes between species that would not typically allow for genetic exchange.Transgenic organisms, commonly referred to as genetically modified organisms (GMOs), are living beings that have undergone deliberate genetic alteration through artificial means that cannot be achieved through traditional breeding methods. These modified organisms have a wide range of applications, including utilization in the fields of agriculture, medicine, and research.It's important to acknowledge that the field of transgenics has progressed significantly, and newer methods like CRISPR-Cas9 now enable more precise and effective gene editing. As a result, genetic modifications can be focused on without the need to introduce genes from other species. It's crucial to differentiate between transgenics and gene editing when discussing genetic manipulation. Scientists are continuously exploring novel techniques, enhancing existing ones, and contemplating the ethical, social, and regulatory consequences of their research.
LOOP MEDIATED ISOTHERMAL AMPLIFICATION (LAMP): A PROMISING ALTERNATIVE TO PCR IN MOLECULAR DIAGNOSTICS
Authors: Panchal Dr. Rajesh J. , Bamji r. Rukhsar C. , Raval Dr. Kalpesh G.
Published: June 2024

A Loop Mediated Isothermal Amplification (LAMP) is a simple, fast, explicit and cost-effective nucleic acid amplification method comparative to PCR (Polymerase Chain Reaction). It is nucleic acid sequence based, self-sustained sequence replication and strand displacement amplification. This technique uses Bst DNA polymerase and specifically sequenced (designed) four to six primer pairs which recognize total six to eight different target sequences on template strand. As a result of amplification, a large amount of DNA is synthesized, yielding a large pyrophosphate ion as by-product. It is a recognized nucleic acid amplification method offering rapid, accurate and cost-effective diagnosis of infectious diseases.