bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of the Implementation and Effectiveness of Community-Based Brain-Computer Interface Cognitive Group Training in Healthy Community-Dwelling Older Adults: Randomized Controlled Implementation Trial
Authors: Yeo Pei Shi , Nguyen Tu Ngoc , Ng Mary Pei Ern , Choo Robin Wai Munn , Yap Philip Lin Kiat , Ng Tze Pin , Wee Shiou Liang
Published: April 2021

Background

Cognitive training can improve cognition in healthy older adults.

Objective

The objectives are to evaluate the implementation of community-based computerized cognitive training (CCT) and its effectiveness on cognition, gait, and balance in healthy older adults.

Methods

A single-blind randomized controlled trial with baseline and follow-up assessments was conducted at two community centers in Singapore. Healthy community-dwelling adults aged 55 years and older participated in a 10-week CCT program with 2-hour instructor-led group classes twice a week. Participants used a mobile app to play games targeting attention, memory, decision making, visuospatial abilities, and cognitive flexibility. Implementation was assessed at the participant, provider, and community level (eg, reach, implementation, and facilitators and barriers). Effectiveness measures were the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), Color Trails Test 2 (CTT-2), Berg Balance Scale, and GAITRite walkway measures (single and dual task gait speed, dual task cost, and single and dual task gait variability index [GVI]).

Results

A total of 94 healthy community-dwelling adults participated in the CCT program (mean age 68.8 [SD 6.3] years). Implementation measures revealed high reach (125/155, 80.6%) and moderate adherence but poor penetration of sedentary older adults (43/125, 34.4%). The effectiveness data were based on intention-to-treat (ITT) and per-protocol (PP) analysis. In the ITT analysis, single task GVI increased (b=2.32, P=.02, 95% CI [0.30 to 4.35]) and RBANS list recognition subtest deteriorated (b=–0.57, P=.01, 95% CI [–1.00 to –0.14]) in both groups. In the PP analysis, time taken to complete CTT-2 (b=–13.5, P=.01, 95% CI [–23.95 to –3.14]; Cohen d effect size = 0.285) was faster in the intervention group. Single task gait speed was not statistically significantly maintained in the intervention group (b=5.38, P=.06, 95% CI [–0.30 to 11.36]) and declined in the control group (Cohen d effect size = 0.414). PP analyses also showed interaction terms for RBANS list recall subtest (b=–0.36, P=.08, 95% CI [–0.75 to 0.04]) and visuospatial domain (b=0.46, P=.08, 95% CI [–0.05 to 0.96]) that were not statistically significant.

Conclusions

CCT can be implemented in community settings to improve attention and executive function among healthy older adults. Findings help to identify suitable healthy aging programs that can be implemented on a larger scale within communities.

Trial Registration

ClinicalTrials.gov NCT04439591; https://clinicaltrials.gov/ct2/show/NCT04439591
Returning to a Normal Life via COVID-19 Vaccines in the United States: A Large-scale Agent-Based Simulation Study
Authors: Li Junjiang , Giabbanelli Philippe
Published: April 2021

Background

In 2020, COVID-19 has claimed more than 300,000 deaths in the United States alone. Although nonpharmaceutical interventions were implemented by federal and state governments in the United States, these efforts have failed to contain the virus. Following the Food and Drug Administration's approval of two COVID-19 vaccines, however, the hope for the return to normalcy has been renewed. This hope rests on an unprecedented nationwide vaccine campaign, which faces many logistical challenges and is also contingent on several factors whose values are currently unknown.

Objective

We study the effectiveness of a nationwide vaccine campaign in response to different vaccine efficacies, the willingness of the population to be vaccinated, and the daily vaccine capacity under two different federal plans. To characterize the possible outcomes most accurately, we also account for the interactions between nonpharmaceutical interventions and vaccines through 6 scenarios that capture a range of possible impacts from nonpharmaceutical interventions.

Methods

We used large-scale, cloud-based, agent-based simulations by implementing the vaccination campaign using COVASIM, an open-source agent-based model for COVID-19 that has been used in several peer-reviewed studies and accounts for individual heterogeneity and a multiplicity of contact networks. Several modifications to the parameters and simulation logic were made to better align the model with current evidence. We chose 6 nonpharmaceutical intervention scenarios and applied the vaccination intervention following both the plan proposed by Operation Warp Speed (former Trump administration) and the plan of one million vaccines per day, proposed by the Biden administration. We accounted for unknowns in vaccine efficacies and levels of population compliance by varying both parameters. For each experiment, the cumulative infection growth was fitted to a logistic growth model, and the carrying capacities and the growth rates were recorded.

Results

For both vaccination plans and all nonpharmaceutical intervention scenarios, the presence of the vaccine intervention considerably lowers the total number of infections when life returns to normal, even when the population compliance to vaccines is as low as 20%. We noted an unintended consequence; given the vaccine availability estimates under both federal plans and the focus on vaccinating individuals by age categories, a significant reduction in nonpharmaceutical interventions results in a counterintuitive situation in which higher vaccine compliance then leads to more total infections.

Conclusions

Although potent, vaccines alone cannot effectively end the pandemic given the current availability estimates and the adopted vaccination strategy. Nonpharmaceutical interventions need to continue and be enforced to ensure high compliance so that the rate of immunity established by vaccination outpaces that induced by infections.
Predicting the Distribution of Sunda Pangolin (Manis javanica Desmarest, 1822) in Way Canguk Research Station, Bukit Barisan Selatan National Park, Lampung
Authors: Anasari Silvi Dwi , Pusparini Wulan , Andayani Noviar
Published: April 2021

The distribution of a species can help guide the protection activities in their natural habitat. Conversely, the lack of information on this distribution makes the protection strategy of this species difficult. The research was conducted in Way Canguk Research Station, Bukit Barisan Selatan National Park from January until March 2018. The purposes of this research were to create a distribution prediction map of Sunda pangolin (Manis javanica) and estimating the environment variables that most influenced the probability of the distribution. Fourteen points of camera trap coordinates were used for presence data with nine types of environment variables such as elevation, slope, understorey, canopy cover, distance from roads, distance from rivers, distance from villages, food source, and distance from the threat. The result of maxent showed an Area Under the Curve (AUC) value of 0.909 categorized as very good. The highest probability of Sunda pangolin distributions was in the Pemerihan Resort and Way Haru Resort area, while the dominant environmental variables included the distance from the village, the canopy cover, and the distance from threat with the value 47.7; 25.85; and 15.8%, respectively. Prediction maps and environment variables can help to identify the population of Sunda pangolin in the wild and can provide input for the national parks to prioritize protection areas for Sunda pangolin from the increased poaching.
Combined Report on Work Package 6. Deliverable 6.1: Report on the Calibrated and Validated CGE Model with Implemented Scenarios Ready for Use. Deliverable 6.2: A Set of Simulation Results and Case StudiesDevelopment of an Evaluation Framework for the Introduction of Electromobility. Project: DEFINE - Development of an Evaluation Framework for the INtroduction of Electromobility
Authors:   IHS - Institute for Advanced Studies, Schmelzer Stefan , Miess Michael
Published: April 2021

Combined Report on Work Package 6. Deliverable 6.1: Report on the Calibrated and Validated CGE Model with Implemented Scenarios Ready for Use. Deliverable 6.2: A Set of Simulation Results and Case StudiesDevelopment of an Evaluation Framework for the Introduction of Electromobility. Project: DEFINE - Development of an Evaluation Framework for the INtroduction of Electromobility
Особенности определения качественных свой­ств. Требования к лабораториям
Authors: Болдырев И.В. , Селиванова Т.Я.
Published: April 2021

В 2017 году была принята новая редакция международного стандарта, который был переведен на русский язык и вступил в силу в 2019 году – ГОСТ ISO / IEC 17025-2019 Оценка соответствия. Общие требования к компетент­ности испытательных и калибровочных лабораторий. Некоторые положения документа требуют дополнительных разъяснений. Обсуждаются вопросы определения качественных свой­ств объекта, которые не выражаются в единицах измерений. Перечислены и подробно рассмотрены примеры качественных свой­ств, которые могут быть определены. Отмечено, что не разработана общая методология определения качественных свой­ств, поэтому отдельные удачные попытки установить единый подход к методикам определения отдельных групп качественных свой­ств не решают проблему в целом. В результате в стандартах можно встретить описания методик, которые очевидно нельзя признать достаточно полными. Приведены рекомендации по верификации методик определения качественных свой­ств в испытательных лабораториях.
STUDIES OF RELIGIOUS EXPERIENCE: FROM THEORY TO EXPERIMENT
Authors:   Anastasiya A. Zubkovskaya  St. Petersburg State University, ZUBKOVSKAYA ANASTASIYA A.
Published: April 2021

The article presents an analysis of experimental studies of religious experience conducted in the laboratory using medical technologies of electroencephalography (EEG) and tomography (including fMRI, PET, SPECT, etc.). The relevance of the article is due to modern trends in the revision of the role of Humanities in the structure of the scientific knowledge. The article considers early attempts of experimental study of religion from the first half of the 20th century; the author tries to make a relevant periodization of experimental research program in the science of religion. The conclusion summarizes the progress of the considered research program and points to modern trends in Humanities caused by implementation of the experimental methodology.
EVOLUTION OF THE IMAGE OF THE SKY (“TENGER”) IN DAURIAN CULTURE
Authors:   SAYINTANA Hulunbuir University, PING LI ,   LI PING Hulunbuir University, TSYBENOV BAZAR D. ,   BAZAR D. TSYBENOV Institute for Mongolian, Buddhist and Tibetan Studies of SB RAS
Published: April 2021

The article studies the historical transformation of the image of the sky in Daurian culture. The authors analyze the myths and shamanistic rituals of the Daur people. The concept of the sky - “tenger” - refers not only to the sky itself, but also to the tops of deer horns, tree tops, the upper part of human and horse’s heads. The authors compare the Daurian and Buryat shamanistic rituals and reveal many similar points. They come to the conclusion that the ancient people worshiped the image of “tenger” as the sun and the moon. After the Neolithic period, “tenger” worship was expressed in the totemistic cult of eagle. The cult of horse was also associated with the sky worship; Daurs sacrificed white horses and bulls to the sky. The authors find out the solar origin of the fairytale heroes of some Daurian myths as well. The sun also appeared as mother in mythical representation. Ancient people considered the sun and the moon as a man and a woman respectively. In the period of matriarchy, when paired marriages arose, there appeared the Daurian myth of marriage of two siblings to two celestial fairies (dakini)...
FEEDING AND EATING DISORDERS MANAGEMENT IN ADOLESCENCE - COGNITIVE BEHAVIORAL APPROACH
Authors: Cano Cláudia Gomes , Pires Sandra , Serrano Ana Catarina
Published: April 2021

Feeding and Eating Disorders (FED) are amongst the most frequent and severe psychiatric disorders in adolescence. These disorders can be considered an important public health issue, since they mostly affect a young population with potential significant functional impact at a young age and throughout adult life. Cognitive behavioral approach has demonstrated evidence as one of the empirically validated reference treatments for all FED. This article aims to perform a narrative review of the cognitive behavioral conceptualization and treatment approach of FED. Enhanced Cognitive Behaviour Therapy (CCT-E) is the treatment of choice for adolescents with FED when Family Therapy is contraindicated, not accepted, or not effective. Furthermore, the importance of an early intervention is emphasized, since it has been demonstrated that CCT-E has more effective results and in a shorter period of time in adolescents compared with an adult population.
Improving the cold flow properties of biodiesel from waste cooking oil by ternary blending with bio-based alcohols and diesel from direct coal liquefaction
Authors: Xue Yuan , Wang Lihong , Lin Hualin , Han Sheng , Zheng Shiyou
Published: April 2021

The utilization and popularization of biodiesel are always limited by
its poor cold flow properties. Both bio-based alcohol and diesel from
direct coal liquefaction (DDCL) has potential to enhance the cold flow
properties of biodiesel. Ternary blends of waste cooking oil biodiesel
(BWCO) with DDCL and bio-based ethanol (ET) or 1-butanol (BT) for
improving the cold flow properties of biodiesel. The pour point (PP),
cold filter plugging point (CFPP), and cloud point (CP) of BWCO-ET,
BWCO-BT, and BWCO-DDCL binary blends, and BWCO-ET-DDCL and BWCO-BT-DDCL
ternary blends were comparatively assessed. Ternary phase diagrams were
also applied into analyze the blending effect of the three components on
the cold flow properties of biodiesel. Results showed that both DDCL, ET
and BT can remarkably enhance the cold flow properties of BWCO. BT and
DDCL presented a better synergistic depression effect. For ternary
blends in 20:10:70 blending ratio, BWCO-BT-DDCL exhibited the lowest PP,
CFPP, and CP of −23 °C, −19 °C, and −17 °C, respectively. The
crystallization behavior and crystal morphology of blended fuels are
also observed via a polarizing optical microscope, and find that DDCL
together with BT in biodiesel can effectively retard the aggregation of
large crystals and inhibit crystals growth.
Are HoLEP Surgical Videos on YouTube Biased and Misleading or Are They Leading the Industry?
Authors: Koras Omer , Gokalp Fatih , Yıldırak Ekrem , Sigva Hakan , Tamgaç Nezih , Porgali Sefa Burak , Kulak Bilal , Uçurmak Ferhat , Gorur Sadik
Published: April 2021

Objective: In this study, we aim to evaluate the content and quality of
the most relevant YouTube videos related to Holmium laser enucleation of
the prostate (HoLEP) surgery. Materials and Methods: The keywords
‘HOLEP’, ‘laser enucleation’ and ‘prostate enucleation’ were used to
perform a search on YouTube. Non-English language videos, videos with
less than 4-minute duration, and repetitive videos were excluded. The
reactions of the viewers to the videos were evaluated by recording the
‘total views’, ‘views/month’ and ‘likes and dislikes’ parameters. The
data were divided into two groups based on the source of upload: Group 1
consisted of healthcare providers and Groups 2 comprised commercial
companies and for-profit organizations. Results: A total of 117 videos
were included in the study. A significant portion of the videos (77.7%)
had been uploaded by healthcare providers. There was no statistically
significant difference between the uploading groups in terms of the
DISCERN and GQS scores (p=0.484 and p=0.108, respectively). However, the
PEMAT understandability and actionability scores were statistically
significantly higher in Group 2 (p=0.004 and p=0.022, respectively). In
addition, when the misinformation scale was evaluated, there were
significantly more videos with high-degree misinformation in Group 2
(5.5% vs 33.3, p=0.001). Conclusion: On video sharing platforms, such
as YouTube, the number of reliable videos with accurate and appropriate
guidance about diseases and treatments should be increased, and these
videos should be allowed to be posted after they have been approved by
relevant institutions, including healthcare associations and
universities.
Telehome monitoring of symptoms and lung function in children with asthma
Authors: Fossati Audrey , Challier Caroline , Dalhoumi Aman , Rose Javier , Galodé François , Fayon Michael
Published: April 2021

Background: The ability to perceive bronchial obstruction is
variable in asthma. This is one of the main causes of inaccurate asthma
control assessment, on which therapeutic strategies are based.
Objective: Primary: To evaluate the ability of a
clinical and spirometric telemonitoring device to characterize symptom
perception profile in asthmatic children. Secondary: To evaluate
its impact on asthma management (control, treatment, respiratory
function variability) and the acceptability of this telemonitoring
system. Method: 26 asthmatic children aged 6-18 years equipped
with a portable spirometer and a smartphone application were monitored
remotely for 3 months. Clinical and spirometric data were automatically
transmitted to a secure internet platform. A medical team contacted the
patient to optimize management. Three physicians blindly and
independently classified the patients according to their perception
profile. The impact of telemonitoring on the quantitative data was
assessed at the beginning (T0) and end (T3 months) of telemonitoring,
using matched statistical tests. Results: Patients could
initially be classified according to their perception profile, with a
concordance between the 3 observers of 64% (kappa coefficient: 0.55,
95%CI [0.39; 0.71]). After further discussion, a consensus was
reached and resulted in 97% concordance (kappa coefficient: 0.97,
95%CI [0.91; 1.00]). There was a trend towards improvement in the
ACT score, and a significant > 40% decrease in FEV1 and
PEF variability, with good acceptance of the device.
Conclusion: Clinical and spirometric telehome monitoring is
applicable and can help define the perception profile of bronchial
obstruction in asthmatic children. The device was generally well
accepted.
Antenatal diagnosis of Double chambered Left Ventricle. Post-natal evolution to LV dysfunction
Authors: Vaksmann Guy , Coudoux Elodie , Dubois Angelina
Published: April 2021

Double chambered left ventricle is an exceedingly rare congenital
anomaly. We report a case diagnosed prenatally at 24 weeks of gestation
and its postnatal evolution to left ventricular dysfunction.
RELIABILITY OF BLADDER VOLUME DETERMINATION IN CHILDREN BY PORTABLE ULTRASONOGRAPHIC SCANNER IN STANDING POSITION
Authors: CEYLAN TANER , Dogan Hasan Serkan , Citamak Burak , Gasimov Kamranbay , Bozaci Ali Cansu , Tatanis Vasileios , Tekgul Serdar
Published: April 2021

Aim: We aimed to compare pre-voiding bladder and post-voiding residual
(BV, PVR) volumes measured by portable ultrasonic scanner (PUS) in
standing and supine positions. Material and Methods: A total of 436
children were included. We composed 2 groups (group-1: PUS vs. volume by
catheter, group-2: PUS vs. infused volume during urodynamic study) to
evaluate the agreement of PUS measurements with actual bladder volume
and then third group (group-3) to analyze the correlation of PUS
measurements in standing vs. supine positions. In groups 1 and 2,
agreement of measurements were evaluated by paired sample T or Wilcoxon
signed rank tests. Following confirmation of agreement, correlations
were analyzed by Pearson’s or Spearman’s coefficients in all groups.
Interpretation of coefficients were done as 0.90-1.00 (very high
correlation) and 0.70-0.90 (high correlation), respectively. Results: In
group-1, measurements (catheter vs. PUS) were similar (Wilcoxon Signed
rank test, p= 0.976) and were highly correlated (r=0.873). In group-2,
measurements of bladder volumes infused by urodynamic device and volumes
by PUS were similar that revealed the agreement of PUS measurements on
different volumes and highly correlated at the 25th and very highly
correlated at the 50th, 75th and 100th percentiles of the EBC (estimated
bladder capacity related to age). In group-3, BV and PVR measurements by
PUS in standing and supine positions were highly correlated that
revelaed PUS can be used in both positions. Conclusion: Measurements of
BV before uroflowmetry or PVR volume by PUS in standing position gave
similar results with those in supine position.
AL-QURAN DAN PLURALISME
Authors: Saihu Saihu
Published: April 2021

Tulisan ini membahas tentang argumentasi Al-Quran terhadap paham pluralisme agama. Dalam tulisan ini, penulis memfokuskan kajiannya pada bagaimana teks agama dan literatur Islam menyikapi pluralitas beragama dan sikap individu dalam konteks masyarakat yang multikultural. Berdasarkan pemahaman atas ayat-ayat Al-Quran yang dikumpulkan dan pendapat para sarjana, penulis berargumen bahwa pluralisme agama merupakan desain Tuhan atau sunnatullah yang mengejawantah dalam kehidupan manusia di bumi. Lebih jauh lagi, penulis memaparkan paham pluralisme memiliki tiga komponen penting yang dapat dijadikan landasan dalam berinteraksi di tengah masyarakat multiagama dan budaya. Tiga komponen itu antara lain: keterlibatan aktif (active engagement); pemahaman mendalam atas perbedaan (constructive understanding); penyamaan persepsi (encounter commitment), atau dalam terminologi agama disebut ummatan wasathān (umat pertengahan). Jika tiga komponen ini diaktualisasikan dalam kehidupan bermasyarakat, maka akan tercipta masyarakat yang madani, yaitu masyarakat yang inklusif, humanis, egalitarian, toleran, dan demokratis, tidak dibatasi oleh perbedaan-perbedaan dan memiliki akses penuh terhadap setiap kegiatan publik.
DINAMIKA KALIGRAFI MUSHAF STANDAR INDONESIA
Authors: Akbar Ali
Published: April 2021

Sejak penetapan Mushaf Standar Indonesia (MSI) pada tahun 1984, MSI Usmani yang ditulis oleh kaligrafer Muhammad Syadzeli telah ditulis ulang dua kali, yaitu pada tahun 2001 oleh Ustadz Baiquni Yasin, dan 2019 oleh Ustadz Isep Misbah. Sementara itu, MSI Bahriyah ditulis oleh kaligrafer Abdul Razak Muhili, 1988. Dalam perkembangannya, memasuki tahun 2000-an, seiring dengan kemajuan teknologi percetakan, MSI juga dicetak dengan modifikasi kaligrafi Mushaf Madinah yang ditulis oleh kaligrafer asal Suriah, Usman Taha. Pada masa belakangan ini, kaligrafi modifikasi Mushaf Madinah semakin banyak digunakan oleh para penerbit mushaf di Indonesia, meninggalkan jauh kaligrafi yang ditulis oleh para penulis tempatan. Tulisan ini hendak melihat dinamika penggunaan atau pilihan kaligrafi dalam MSI, didahului dengan latar belakang historis perkembangan mushaf di Asia Tenggara. Lamanya peredaran mushaf cetakan Bombay di Indonesia, dengan ciri kaligrafi tebal, membawa pengaruh terhadap pilihan kaligrafi MSI, meskipun kemudian tergeser oleh gaya kaligrafi Mushaf Madinah yang tipis sejak tahun 2000-an.
Revista GEON Vol 6 No 1 enero junio 2019
Authors: GEON Revista
Published: April 2021

Para esta edición contamos con unas reflexiones editoriales sobre el entrenamiento de los colaboradores relacionado con la formación en herramientas mentoring,  con un aporte de las competencias genericas revisada desde la BUAP, esto concatenado con las estrategias para el liderazgo como es el uso de herramientas tecnologicas, mencionando la gestión de la calidad, la auditoría administrativa, el análisis del riesgo financiero en el sector salud y estrategias comerciales, acompañado de herramientas para los aspectos socioeconómicos y del espacio público
Conflict resolution using relation classification: High-level data fusion in data integration
Authors: Nakhaei Zeinab , Ahmadi Ali , Sharifi Arash , Badie Kambiz
Published: April 2021

The aim of conflict resolution in data integration systems is to identify the true values from among different and conflicting claims about a single entity provided by different data sources. Most data fusion methods for resolving conflicts between entities are based on two estimated parameters: the truthfulness of data and the trustworthiness of sources. The relations between entities are however an additional source of information that can be used in conflict resolution. In this article, we seek to bridge the gap between two important broad areas, relation estimation and truth discovery, and to demonstrate that there is a natural synergistic relationship between machine learning and data fusion. Specifically, we use relational machine learning methods to estimate the relations between entities, and then use these relations to estimate the true value using some fusion functions. An evaluation of the results shows that our proposed approach outperforms existing conflict resolution techniques, especially where there are few reliable sources.
The role of emotional competencies in psychological responding to COVID-19 pandemic
Authors: Kozina Ana , Vidmar Masa , Veldin Manja , Pivec Tina , Peras Igor
Published: April 2021

With stress related to the COVID?19 pandemic, an increase in anxiety and a decrease in overall mental well-being is expected. We investigated the role of emotional competencies (mindfulness and emotional self-efficacy) for psychological responding (mental well-being, general anxiety, and COVID?19 anxiety) during the COVID?19 pandemic. We also examined whether practising mindfulness with inner (meditation-based) and body (yoga-based) exercises supports emotional competencies. Our sample consisted of 364 participants (83.5% females, M = 37.21 years, SD = 12.92 years). Findings showed that emotional competencies are a viable source of support in psychological responses to COVID?19, with Emotional self-efficacy and Accept without judgement playing the strongest roles. Moreover, practising mindfulness was shown to foster several aspects of emotional competencies (i.e., Observe, Describe, and Emotional self-efficacy). There is an ambiguous finding regarding Observe scale that was also found problematic in other studies. The implications for possible interventions are discussed.
Metformin’s Therapeutic Action in the Treatment of Diabetes Does Not Involve Inhibition of Mitochondrial Glycerol Phosphate Dehydrogenase
Authors: MacDonald Michael J. , Ansari Israr-ul H. , Longacre Melissa J. , Stoker Scott W.
Published: April 2021

Mitochondrial glycerol
phosphate dehydrogenase (mGPD) is the rate-limiting enzyme of the glycerol
phosphate redox shuttle. It was recently claimed that metformin, a first line
drug used for the treatment of type 2 diabetes, inhibits liver mGPD 30-50%
suppressing gluconeogenesis through a redox mechanism. Various factors cast
doubt on this idea. Total body100% knockout of mGPD in mice has adverse effects
in several tissues where mGPD is high, but has little or no effect in liver
where mGPD is the lowest of ten tissues. Metformin has beneficial effects in
humans in tissues with high levels of mGPD such as pancreatic beta cells where
mGPD is much higher than in liver. Insulin secretion in mGPD knockout mouse
beta cells is normal because, like liver, beta cells possess the malate
aspartate redox shuttle that’s redox action is redundant to the glycerol
phosphate shuttle. For these and other reasons we used four different enzyme
assays to reassess whether metformin inhibited mGPD. Metformin did not inhibit
mGPD in homogenates or mitochondria from insulin cells or liver cells. If metformin
actually inhibited mGPD, adverse effects in tissues where the level of mGPD is
much higher than in liver could prevent metformin’s use as a diabetes medicine.
A Numerical Study on the Melting Behaviors of Paraffin with and without Al2O3 Nanoparticles
Authors: ARSLAN Büşra , İLBAŞ Mustafa
Published: April 2021

One of the most effective methods of thermal energy storage is the use of Phase Change Materials (PCM). Paraffin, which is among the organic PCMs, is frequently used in thermal storage applications due to its easy accessibility and high heat storage capacity. However, it significantly limits the thermal charge / discharge (melting / solidification) rate of systems caused by their low thermal conductivity. There are many methods applied to enhance the thermal conductivity of paraffin. In this research, the melting processes of pure paraffin (Rubitherm RT50) and paraffin containing 10% Al2O3 nanoparticle in a rectangular melting area were numerically investigated. For comparison, the effect of increasing the wall temperature of the rectangular area to 65 ° C, 70 ° C and 75 ° C on the total melting time was investigated for both pure paraffin (melting temperature 50 ° C) and paraffin with nanoparticle additives. In this study, in which the Computational Fluid Dynamics (CFD) approach was used, ANSYS Fluent software was used to perform numerical analysis. Consequently it was determined that the use of Al2O3 nanoparticles improved the rate of paraffin heat transfer.
NEURAL NETWORK MODEL FOR IDENTIFICATION OF MATERIAL CREEP CURVES USING CUDA TECHNOLOGIES
Authors:   Ukrainian National Forestry University, Sokolovskyy Ya. I. , Shymanskyi V. M. ,   Ukrainian National Forestry University, Mokrytska O. V. ,   Ukrainian National Forestry University, Kharko Ya. V. ,   Ukrainian National Forestry University
Published: April 2021

This pa­per addres­ses the prob­lem of iden­tif­ying rhe­olo­gi­cal pa­ra­me­ters of wo­od using ar­ti­fi­ci­al neu­ral net­works with pa­ral­lel le­ar­ning al­go­rithm using Python prog­ram­ming lan­gua­ge, Cha­iner fra­me­work and CU­DA techno­logy. An in­tel­li­gent system for iden­ti­fi­ca­ti­on of rhe­olo­gi­cal pa­ra­me­ters of wo­od has be­en de­ve­lo­ped. The system cre­ated con­ta­ins the most user-fri­endly in­ter­fa­ce, all the ne­ces­sary set of to­ols for au­to­ma­ti­on of the pro­cess of vis­ua­li­za­ti­on and analysis of da­ta. In the pro­cess of cre­ati­on of the in­tel­lec­tu­al system, the fol­lo­wing tasks we­re en­vi­sa­ged: to carry out the analysis of ar­ti­fi­ci­al in­tel­li­gen­ce systems and the analysis of tra­ining of ar­ti­fi­ci­al neu­ral net­works, in par­ti­cu­lar mul­ti­la­yer neu­ral net­works of di­rect pro­pa­ga­ti­on, re­cur­rent neu­ral net­works and the Ko­ho­nen neu­ral net­work; exa­mi­ne the struc­tu­re of the Cha­iner fra­me­work and its in­te­rac­ti­on with CU­DA; to con­duct exis­ting clo­ud techno­lo­gi­es to ac­complish the task; to con­duct the analysis of al­go­rithms of stu­di­es of ar­ti­fi­ci­al neu­ron net­works, the­ir mat­he­ma­ti­cal pro­vi­ding; to imple­ment pa­ral­le­li­za­ti­on of le­ar­ning al­go­rithms and to de­ve­lop the ne­ces­sary softwa­re. Using Cha­iner al­lows you to cre­ate a me­mory po­ol for GPU me­mory al­lo­ca­ti­on. To avo­id me­mory al­lo­ca­ti­on and era­su­re du­ring com­pu­ting, Cha­iner pro­vi­des the abi­lity to use the CuPy me­mory po­ol as a stan­dard me­mory al­lo­ca­ti­on wit­ho­ut de­aling with me­mory al­lo­ca­ti­on. An in­tel­lec­tu­al system to de­ter­mi­ne the physi­cal and mec­ha­ni­cal pa­ra­me­ters of a mat­he­ma­ti­cal mo­del of non-isot­her­mal mo­is­tu­re transfer and vis­co­elas­tic de­for­ma­ti­on of ca­pil­lary-po­ro­us ma­te­ri­als was de­ve­lo­ped. It pro­vi­des the op­por­tu­nity to iden­tify pa­ra­me­ters of the ker­nels of cre­ep and re­la­xa­ti­on that is writ­ten as a li­ne­ar com­bi­na­ti­on of ex­po­nen­ti­al ope­ra­tors. The pro­po­sed al­go­rithm of appro­xi­ma­ti­on and ob­ta­ined cal­cu­la­ted ra­ti­os of rhe­olo­gi­cal be­ha­vi­or of wo­od by me­ans of mul­ti­la­yer neu­ral net­work with ex­po­nen­ti­al ac­ti­va­ti­on functi­ons in hid­den la­yers al­lows to incre­ase the ac­cu­racy of appro­xi­ma­ti­on of ex­pe­ri­men­tal cre­ep da­ta. The de­ve­lo­ped mat­he­ma­ti­cal mo­dels can be used to cre­ate an au­to­ma­ted systems of fi­ni­te-dif­fe­ren­ce cal­cu­la­ti­on of tem­pe­ra­tu­re and mo­is­tu­re con­tent, stress com­po­nents du­ring the drying of ca­pil­lary-po­ro­us ma­te­ri­als with ta­king in­to ac­co­unt the techno­lo­gi­cal pa­ra­me­ters of the drying agent.
INVESTIGATION OF TIME SCALING FOR THE INVERTED BETA FUNCTIONS
Authors:   Lviv Polytechnic National University, Dronyuk I. M. , Shpak Z. Ya. ,   Lviv Polytechnic National University, Demyda B. A. ,   Lviv Polytechnic National University
Published: April 2021

The use of Ateb-functi­ons is de­ter­mi­ned by tho­se are­as whe­re or­di­nary tri­go­no­met­ric functi­ons are used. Mo­dern ad­van­ces in physics ha­ve led to the de­ve­lop­ment of new mat­he­ma­ti­cal are­as that req­ui­re the re­la­ti­vity or va­ri­abi­lity of ti­me. The cur­rent re­se­arches in this fi­eld and ma­in re­sults of stu­di­es of the or­di­nary Ateb functi­ons are bri­efly descri­bed. To ta­ke in­to ac­co­unt compres­si­on/slow-down as a pro­perty of ti­me pa­ra­me­ter, the q-ana­logs of Ateb-si­ne (q-Ateb-si­ne) and Ateb-co­si­ne (q-Ateb-co­si­ne) are construc­ted by in­ver­ting the in­comple­te q-Be­ta functi­ons. The chan­ge in pa­ra­me­ter q cor­res­ponds to the ti­me sca­ling in the stu­di­es. q-ana­logs of Ateb-tan­gent (q-Ateb-tan­gent), Ateb-co­tan­gent (q-Ateb-co­tan­gent), Ateb-se­cant (q-Ateb-se­cant) and Ateb-co­se­cant (q-Ateb-co­se­cant) are intro­du­ced. The­orems cha­rac­te­ri­zing the ba­sic pro­per­ti­es of the construc­ted functi­ons are pro­ved. In par­ti­cu­lar, it is shown that when q→1, ta­king the li­mit we ob­ta­in or­di­nary Ateb-functi­ons. The intro­du­ced functi­ons are pe­ri­odic with the pe­ri­od cor­res­pon­ding to q-ana­log­ue pe­ri­ods of the or­di­nary Ateb-functi­ons. The rep­re­sen­ta­ti­on of the pe­ri­od using the q-ana­log­ue of the Gam­ma-functi­on is construc­ted. The ge­ne­ra­li­zed Pytha­go­re­an iden­tity for the q-ana­log­ues of tri­go­no­met­ric Ateb-functi­ons is pro­ved. Al­so the pro­per­ti­es of the pa­rity and od­dity of the­se functi­ons are con­si­de­red and pro­ved. The in­ter­vals of incre­asing/dec­re­asing for all functi­ons are fo­und. The q-ana­log­ues of the iden­ti­ti­es for­mu­las for the tri­go­no­met­ric Ateb-functi­ons are pre­sen­ted. For­mu­las for cal­cu­la­ting q-de­ri­va­ti­ves for the q-ana­log­ue of tri­go­no­met­ric Ateb-functi­ons are construc­ted. It is pro­ved that construc­ted functi­ons sa­tisfy the system of q-de­ri­va­ti­ve dif­fe­ren­ti­al eq­ua­ti­ons. Re­sults of the pre­sen­ted stu­di­es can be used in the ti­me se­ri­es the­ory and sig­nal pro­ces­sing.
BINARY LINEAR TRANSFORMATIONS IN MODIFICATIONS OF RSA ALGORITHM OF IMAGES
Authors:   Lviv Polytechnic National University, Kovalchuk A. M.
Published: April 2021

The images are one of the most used kinds of the information in modern information company. Therefore actual problems is the organization of protection from unauthorized access and usage. An important characteristic of the image is the presence of contours in the image. The task of contour selection requires the use of operations on adjacent elements that are sensitive to change and suppress areas of constant levels of brightness, that is, contours are those areas where changes occur, becoming light, while other parts of the image remain dark. Mathematically, the ideal outline is to break the spatial function of the brightness levels in the image plane. Therefore, contour selection means finding the most dramatic changes, that is, the maxima of the gradient vector module. This is one of the reasons that the contours remain in the image when encrypted in the RSA system, since the encryption here is based on a modular elevation of some natural number. At the same time, on the contour and on the neighboring contours of the peak villages, the elevation of the brightness value gives an even bigger gap. Problem protect from unauthorized access is by more composite in matching with a problem protect from usage. Basis for organization of protection is the interpretation of the image as stochastic signal. It stipulates carry of methods of encoding of signals on a case of the images. But the images are a specific signal, which one in possesses, is padding to representative selfless creativeness, also by visual selfless creativeness. Therefore to methods of encoding, in case of their usage concerning the images, one more requirement – full noise of the coded image is put forward. It is necessary to make to impossible usage of methods of visual image processing. The algorithm RSA is one of the most used production specifications of encoding of signals. In attitude of the images there are some problems of its encoding, the contours on the coded image are in particular saved. Therefore actual problem is the mining of modification to a method RSA such, that: to supply stability to decoding; to supply full noise of the images. One of pathes of the solution of this problem is usage of affine transformations.
DEVELOPMENT OF A MODERN E-LEARNING SYSTEM IN THE UNIVERSITY
Authors:   National Technical University ", Kukharenko V. M. ,   Kharkiv Polytechnic Institute"
Published: April 2021

This paper analyzes the world sources and considers the evolution of the e-learning system in the world, which are necessary for the formation of the e-learning system of the educational institution. The object of research is modern information pedagogical technologies that change the educational process. Subject of research – various educational technologies (distance, mixed, mobile, micro-) learning that influence the effectiveness of the educational process. The purpose is to identify the main elements that create the global e-learning system and to define the structure of the system for use in educational institutions. It is shown that in the first stage distance courses played the role of delivery of educational materials to the student. The development of web 2.0 technology and the advent of LMS have changed the way we learn. Pedagogical theories, the pedagogical instructional model ADDIE, and the use of Bloom's taxonomy allowed for student collaboration and active communication. The distance learning course is focused on achieving and measuring learning outcomes. In the third stage, all components of the world eLearning system are present: methodical, informational, technological, software and technical, personnel, regulatory, planning and development, monitoring and control. The components of the subsystems are variable in nature. Such a system is the basis for the strategy and tactics of the development of the e-learning system in the educational organization and its structural units. The most important is the planning and development subsystem, which defines the ways of development of the educational organization, the strategy and tactics of development of the e-learning system of the university, the required staff potential and the system of professional development of teachers. For its effective work it is necessary to have trained content curators who follow the most influential content curators of the world. Members of this team provide certification for distance courses in accordance with the organization standard. National Technical University "Kharkiv Polytechnic Institute" conducts systematic work in this area, conducts open distance courses for developers, tutors, content curators and experts for teachers of educational institutions of Ukraine. Developed distance courses that measure the competence of trained professionals ensure high efficiency of dual learning. More than 2,100 teachers of educational establishments of Ukraine have enrolled in the open distance courses, more than 320 teachers have successfully completed the courses.
INFORMATION COMPETENCE OF UNIVERSITY STUDENTS AS TRANSPROFESSIONAL
Authors: Табачук Наталья Петровна
Published: April 2021

Подчеркивается влияние цифровой трансформации на «парк профессий» и подготовку студентов вуза как транспрофессионалов с высоким уровнем развития информационной компетенции. Информационную компетенцию студентов вуза необходимо рассматривать как транспрофессиональную компетенцию и как социокультурный феномен одновременно. Информационная компетенция как социокультурный феномен включает в себя культуру работы с профессиональным контекстом как трансформацией информации в тексты собственного сознания; культуру представления образовательных результатов в виде цифрового продукта; культуру управления своей деятельностью в целях информационной безопасности; культуру работы с информацией в аспекте релевантности; культуру мобильного решения профессиональных задач с помощью цифровых технологий; культуру работы с цифровым контентом, представляемым в цифровой образовательной среде, что характеризует информационную компетенцию как транспрофессиональную. Потенциал «парка профессий» расширяет границы понимания информационной компетенции студентов вуза как транспрофессиональной.

The article emphasizes the impact of digital transformation on the “park of professions” and the training of university students as transprofessionals with a high level of development of information competence. The increased interest in career guidance projects allows us to determine the potential of the “park of professions” for the development of transprofessional information competence of university students. Transprofessional competencies, one of which is information competence, are the skills of the future (future skills). Hard skills – (English “hard” skills) competencies manifested in the narrow professional sphere, and soft skills – (English “soft” skills) as transprofessional competencies acquired and developed throughout life, characterized by moving beyond one profession. The information competence of university students should be considered as a transprofessional competence and as a sociocultural phenomenon at the same time. Information competence as a socio-cultural phenomenon includes a culture of working with a professional context as a transformation of information into texts of one’s own consciousness; culture of presentation of educational results in the form of a digital product; a culture of information security management; a culture of working with information in relation to relevance; culture of mobile solution of professional tasks with the help of digital technologies; a culture of working with digital content presented in a digital educational environment, which characterizes information competence as well as transprofessional. The potential of the “park of professions” expands the boundaries of understanding the information competence of university students as transprofessional.
SOCIOCULTURAL APPROACH AS AN IMPERATIVE OF THE EDUCATIONAL ACTIVITIES OF A MODERN MUSEUM
Authors: Бакиева Диана Айратовна
Published: April 2021

Рассматривается социокультурный подход как основание современного образования, ориентированного на личность в полноте ее культурно-воспроизводительной деятельности. Исследуется связь социокультурного подхода и музея, обусловливающая изменение образовательной деятельности последнего. Актуализируется проблема расширения образовательных возможностей музея, обострившаяся в условиях социальной необходимости поиска альтернативных методов взаимодействия с личностью. Обращение к социокультурному подходу как методологии деятельности музея позволяет изменить конфигурацию общения, в качестве цели обозначив включение в процесс коммуникации личность человека как равнозначного субъекта коммуникации наравне с культурой и социумом. В соответствии с запросом общества музейная коммуникация как метод сотрудничества с личностью в образовательной практике музея становится первостепенной. Анализ образовательной деятельности музея позволяет проследить влияние коммуникационных процессов, трансформирующих содержание, образовательную среду и результаты образования в музее, придавая им личностно значимые смыслы. Следовательно, присвоение личностью разнообразия социокультурного опыта становится ключевой задачей образовательной деятельности музея, что отвечает современной социокультурной ситуации.

The article examines the sociocultural approach as the basis of modern education focused on the individual in the fullness of his cultural and reproductive activity. The relationship between the socio-cultural approach and the museum is investigated, which determines the change in the educational activity of the latter. In accordance with the demands of society, museum communication as a method of interaction with a person in the educational practice of the museum becomes paramount. Museum communication and the process of its transformation in the digital age is a key concept for studying the mechanisms of modernization of the educational activities of the museum. In turn, communicative processes transform the content and results of education in the museum, giving it personally meaningful meanings. The semantic field of the content of museum education becomes the basis for communication, and the museum visitor is a representative of one or another point of view on cultural phenomena. The museum, being at the junction of various sciences (pedagogy, psychology, museology, art history), sees its goal not so much in the expansion of knowledge, but in the development of the value apparatus, attitudes, and creative abilities of the individual. Consequently, the appropriation by an individual of the diversity of sociocultural experience becomes a key task of the educational activities of the museum.
FEATURES OF THE USE OF DISTANCE LEARNING TECHNOLOGIES IN THE ORGANIZATION OF THE EDUCATIONAL PROCESS AT THE UNIVERSITY
Authors: Алмазова Ирина Геннадьевна , Кондакова Ирина Владимировна , Нехороших Наталья Александровна
Published: April 2021

Подчеркивается необходимость своевременного вычленения и качественного анализа проблем дистанционного обучения, учета предпочтений и интересов обучающихся и преподавателей вуза, консолидации их усилий по преодолению трудностей и решению проблем, связанных с объективными и субъективными ситуациями, особенностями использования технологий дистанционного обучения при организации образовательного процесса в университете. Описаны особенности использования дистанционной формы организации обучения в вузе. Приведены данные, полученные при исследовании (опросе) влияния применения технологий дистанционного обучения на здоровье студентов 1–5-го курсов очной и заочной формы обучения направления подготовки 44.03.05 Педагогическое образование (с двумя профилями подготовки) Института психологии и педагогики Елецкого государственного университета им. И. А. Бунина.

The article describes the need for timely identification and qualitative analysis of the problems of distance learning, taking into account the preferences and interests of students and university teachers, consolidating their efforts to overcome difficulties and solve problems related to objective and subjective situations, the peculiarities of using distance learning technologies in the organization of the educational process at the university. In the current situation, burdened by the spread of a new coronavirus acute respiratory infection, which is caused by the coronavirus SARS-CoV-2 (2019-nCoV), the world education system (including higher education) is forced to turn to distance learning technologies. These technologies allow you to work remotely, maintaining the necessary distance, protecting the health of people (both students, teachers, and employees of higher educational institutions), excluding their close interaction during training, scientific research, in the admission campaign, in extracurricular work, etc. The authors describe the features of using the remote form of organizing training at the university so that it contributes to the maximum saving of students ‘ health, has a positive effect on their physical and mental state; minimizes the viral load in a difficult epidemiological situation; increases and develops digital literacy of students; “opens” new opportunities for remote work for the teaching staff. The article provides the data obtained in the study (survey) of the impact of the use of distance learning technologies on the health of the full-time and part-time students of the 1st – 5th year of studies of the area of training 44.03.05 Pedagogical education (with two training profiles) of the Institute of Psychology and Pedagogy Bunin Yelets State University.