bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS AKUNTABILITAS DAN TRANSPARANSI PENGELOLAAN BUMDES BINA SEJAHTERA KEMBANG KERANG, KABUPATEN LOMBOK TIMUR
Authors: Akbar Abdul Malik , Sasanti Elin Erlina , Suryantara Adhitya Bayu
Published: December 2022

Penelitian ini menganalisis tentang akuntabilitas dan transparansi pengelolaan pada salah satu BUMDes yang ada di Kabupaten Lombok Timur yakni BUMDes Bina Sejahtera di Desa Kembang Kerang. Tujuan dari penelitian ini adalah untuk mengetahui sejauh mana akuntabilitas dan transparansi BUMDes Bina Sejahtera ke pihak pemerintah desa dan masyarakat. Penelitian ini menggunakan pendekatan kualitiatif deskriptif, dengan pengumpulan data melalui observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukkan bahwa BUMDes Bina Sejahtera telah akuntabel dan transparan dalam pengelolaan BUMDes. BUMDes Bina Sejahtera dalam menyusun laporan keuangan menyertakan bukti transaksi, dan untuk laporan keuangan telah memuat laporan posisi keuangan dan laporan laba rugi dengan kelasifikasi akun yang jelas. Untuk dokumen kegiatan BUMDes telah tersedia lengkap dan bisa diakses oleh masyarakat langsung ke Kantor BUMDes Bina Sejahtera. Pengelolaan kegiatan BUMDes dilaporkan setiap setahun sekali dalam musyawarah desa ke pihak pemerintah desa dan masyarakat.
ANALISIS PENGARUH PROFITABILITAS, MANAGERIAL AGENCY COST DAN GOOD CORPORATE GOVERNANCE TERHADAP FINANCIAL DISTRESS (STUDI KASUS PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BEI TAHUN 2018-2020)
Authors: Ihvan Muh.Zaky , Karim Nina Karina , Hudaya Robith
Published: December 2022

Tujuan dalam penelitian ini adalah untuk menganalisa pengaruh profitabilitas, managerial agency cost dan good corporate governance terhadap financial distress pada perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia pada tahun 2018-2020. Populasi dalam penelitian ini adalah perusahaan manufakturl yang terdaftar di Bursa Efek Indonesia (BEI) periode 2018-2020. Berdasarkan metode purposive sampling diperoleh 115 perusahaan yang memenuhi kriteria sebagai sampel penelitian. Metode analisis data dalam penelitian ini menggunakan analisis regresi data panel. Hasil penelitian ini membuktikan bahwa profitabilitas, managerial agency cost dan good corporate governance berpengaruh signifikan terhadap financial distress yang diproksikan dengan altman z-score.
Citisiniclina no Tratamento Farmacológico da Cessação Tabágica: Uma Revisão Baseada na Evidência
Authors: Pereira Vicente Ana Filipa , Berezovska Trindade Lourenço Olena
Published: December 2022

INTRODUÇÃO: O tabagismo traduz-se em elevada morbi-mortalidade. Deixar de fumar tem benefícios em qualquer idade. O objetivo desta revisão é determinar o nível de evidência da prescrição de citisiniclina (citisina) no tratamento farmacológico da cessação tabágica (CT).METODOLOGIA: Realizou-se a 9 de dezembro de 2021 uma pesquisa bibliográfica nas bases de dados de estudos publicados nos últimos 10 anos, em inglês e português, utilizando os termos MeSH: “cytisine” e “smoking cessation”. Para estrati?car o nível de evidência e a força de recomendação, foi utilizada a escala SORT da American Academy of Family Physicians.RESULTADOS: Foram encontrados 153 artigos, tendo sido selecionados 14 artigos: 2 meta-análises, 7 revisões sistemáticas e 5 ensaios clínicos controlados randomizados.CONCLUSÃO: Concluiu-se que a citisiniclina apresenta efeitos benéficos na CT, com efeitos secundários ligeiros, pelo que evidência atual permite recomendar a citisiniclina na terapêutica farmacológica da CT (nível de evidência 1, grau de recomendação A).
Infeção por Citomegalovírus na Gravidez: Em que Ponto Estamos?
Authors: Ferreira Marta Fontes , Pereira Hugo , Cardoso Olga Couto , Oliveira Clara , Pereira Mariana Costa , Couto Juliana
Published: December 2022

A infeção por citomegalovírus é a infeção congénita mais frequente no mundo, com uma prevalência de 1,1% em Portugal Continental. A infeção fetal pode cursar com alterações importantes, sendo a principal causa de perda auditiva neurossensorial não hereditária na infância e podendo cursar com alterações congénitas de múltiplos sistemas de órgãos. A proposta de um rastreio universal pré-concecional é debatida há vários anos, não existindo ainda consenso sobre o tema. Dados recentes sugerem que o valaciclovir pode ser um tratamento eficaz e seguro, o que poderá trazer mais um argumento a favor da realização do rastreio universal do citomegalovírus. Este artigo de revisão procura sistematizar a mais recente informação sobre a infeção materna e fetal por citomegalovírus, o seu diagnóstico e possíveis tratamentos, bem como refletir acerca da pertinência da realização de um rastreio pré-concecional e ao longo da gravidez.
Infeções Urinárias em Doentes com Diabetes Mellitus Tipo 2 Tratados com Inibidores do SGLT2: Uma Revisão Baseada na Evidência
Authors: Rocha-Castro Carlos , Lopes Vaz Pedro , Pereira Gomes Carla
Published: December 2022

INTRODUÇÃO: O mecanismo de ação dos inibidores do co-transportador de sódio-glicose 2 (iSGLT2) consiste no aumento da glicosúria. Existe evidência da associação entre a sua toma e a ocorrência de infeções genitais. Porém, a associação com infeções do trato urinário (ITU) não está bem estabelecida. Pretende-se analisar a evidência atual sobre a associação entre iSGLT2 em doentes com diabetes mellitus tipo 2 e a ocorrência de ITU.MÉTODOS: Pesquisadas normas de orientação clínica, meta-análises (MA), revisões sistemáticas e ensaios clínicos controlados e aleatorizados (ECCA) entre outubro de 2011 e outubro de 2021 na The National Institute for Health and Care Excellence, The Cochrane Library e PubMed. Utilizados os termos MeSH “urinary tract infection”, “sodium-glucose transporter 2 inhibitors” e “diabetes mellitus, type 2”. Para atribuição dos níveis de evidência (NE) foi utilizada a escala Strength of Recommendation Taxonomy, da American Academy of Family Physicians.RESULTADOS: Dos 331 resultados identificados, 6 cumpriram os critérios de inclusão: 5 ECCA e 1 MA. Todos classificados com NE 2. A evidência da associação entre a toma de iSGLT2 e ITU foi apenas demonstrada, de forma estatisticamente significativa, na MA e relativamente à dapagliflozina na dosagem de 10 mg.CONCLUSÃO: Os estudos apresentam resultados heterogéneos, inconsistentes e de qualidade moderada. Os iSGLT2 têm afirmado o seu lugar no tratamento de múltiplas patologias pelo que impera a realização de estudos dirigidos à ocorrência de efeitos adversos como a frequência de ITU. Devem ainda compreender amostras de maior dimensão, diferentes moléculas e posologias, para a obtenção de evidência robusta.
Reflexão sobre o papel dos governos distritais na gestão sustentável da mineração artesanal de ouro em Moçambique
Authors: Choé Joao Francisco de Carvalho
Published: December 2022

Este artigo tem como tema papel dos governos distritais na gestão sustentável da mineração artesanal de ouro em Moçambique. Por isso, o objetivo deste estudo consiste em analisar o papel do governo distrital na gestão sustentável da mineração artesanal de ouro face às oportunidades e obstáculos no desenvolvimento daquele distrito. Adotou-se uma abordagem qualitativa. A entrevista foi aplicada a nove pessoas sendo direcionadas aos membros do governo distrital por parte dos serviços distritais de atividades econômicas, geologia e minas, assumindo a hierarquia estabelecida abrangendo a liderança localmente instituída na base, dois membros das associações e garimpeiros individuais incluindo crianças e mulheres. Os resultados obtidos mostraram que há tendências de as autoridades locais intervirem positivamente na gestão sustentável da mineração artesanal de ouro, dado que existe ao nível nacional uma legislação forte que prevê o associativismo mineiro, de modo que os mineradores artesanais.
Immunopathological Responses to the Bovine Mastitis Associated with Staphylococcus Species Infection
Authors: Al-Rasheed Agharid A , Ahmed Sana’a S , Al-Jashamy Karim A , Garba Bashiru
Published: December 2022

Bovine mastitis is a disease that concerns animals' welfare and increases the economic production losses. Bacterial agents such as Staphylococcus species are the main causative agent of bovine mastitis. This bacterial agent expresses some inflammatory cytokines that might enhance the cell-mediated, which may promote the pathogenesis of mastitis. The objective of the current study was to investigate the bovine innate immune response circulating levels of pro-inflammatory and anti-inflammatory cytokines. A total of 10 mL of milk specimens were collected randomly from 100 clinically mastitic cows, and another 20 clinically healthy cows were considered as a control group for the California Mastitis test. The microbiological cultures of milk specimens were performed. The interleukins (ILs)that involved IL-4, IL-6, and IL-10 were detected using the ELISA test for the evaluation of the pro-inflammatory bovine mastitis pathophysiology. The results of this study showed that Staphylococcus aureus detection was in 31.2% of mastitic milk and 8.7% of non-mastitic milk specimens; and the coagulase-negative Staphylococcus was detected in 14.8% and 18.7% in the mastitic and non-mastitic milk specimens, respectively. The IL-6 level was shown significantly higher (P<0.05)in the specimens of mastitic milk (194±12.8 pg/mL) compared to the non-mastitic milk (31±2.9 pg/mL). In conclusion, the elevated level of expression of IL-6 cytokine in the milk of cows with mastitis suggested that IL-6 might be used as a potentially suitable biomarker for early bovine mastitis diagnosis
GELENEKSEL TÜRK TİYATROSUNDAN SİNEMAYA SEYİRLİK MİZAH: ZEKİ ALASYA-METİN AKPINAR FİLMLERİ ÖRNEĞİ
Authors: DURSUN Aysun , DALİOĞLU Gizem
Published: December 2022

İnsanların deneyimlerini, yaşam biçimlerini, geleneklerini aktarmaya katkı sağlayan bir araç olarak tiyatro günlük yaşamda karşılık bulan pek çok olayı veya durumu konu edinir, kişiler aşina olunan tiplerle temsil edilir.
Teknolojik gelişmelerle değişen şartlar, tiyatronun yanında topluma hitap edebilme gücüne sahip olan sinema ve televizyonun da halk arasında geniş bir etki uyandırmasına olanak sağlar. İzleyici, tiyatroda oynadıkları rollerle sevilen tipleri, sinema perdesinde veya televizyon ekranında da görmeyi tercih eder. Bu çerçevede geleneksel Türk halk tiyatrosunda Karagöz ile Hacivat, Kavuklu ile Pişekâr, İhtiyar ile İbiş olarak görülen ikili komiklerin devamı niteliğindeki Zeki-Metin ikilisinin filmlerinde gelenekten beslenen bir mizah anlayışının görüldüğü söylenebilir. İkili arasında yanlış anlama, anlamazlıktan gelme gibi hususlarla yaşanan zıtlaşma, üstün gelme mücadelesi, jest, mimik ve yapılan kalıp hareketler tıpkı geleneksel Türk halk tiyatrosunda olduğu gibi gülmeye yol açar.
Bu çalışmada Zeki Alasya ve Metin Akpınar’ın filmlerinde geleneksel Türk halk tiyatrosunun etkisi karşılaştırmalı yöntemle ele alınarak mizah ve gülme unsurları Henri Bergson’un gülme teorisi bağlamında değerlendirilmiştir.
Pengaruh Beban Kerja dan Lingkungan Kerja terhadap Kinerja Karyawan dengan Stres Kerja sebagai Variabel Intervening pada PT Batanghari Barisan Padang
Authors: Sari Vivi Nila , Safitri Rena , Sulistyowati Eny
Published: December 2022

This study aims to determine how much influence workload and work environment partially and simultaneously on employee performance with work stress as an intervening variable. Sampling was conducted by random sampling technique with the Slovin method to determine 74 respondents who are permanent employees of the company. Analysis of this research used multiple linear regression techniques to find the effect of the independent variables on the dependent variable and used path analysis to examine the effect of the intervening variables. The analysis of the research used the Statistical Product and Service Solution (SPSS) version 21. The results of this study indicate that workload has a negative and insignificant effect on work stress, while the work environment has a positive and significant effect on work stress. Furthermore, workload and work environment have a positive and insignificant effect on employee performance partially. Workload and work environment simultaneously have a positive and significant effect on work stress. In line with these results, workload and work environment simultaneously have a positive and significant effect on employee performance. This study also confirms that work stress is not able to mediate the effects of workload and work environment on employee performance respectively.
The Effect of The Addition of Chitosan and Calcium Silicate on The Characteristic of Bioplastics from Corn Starch
Authors: Jhon Ricky , Haryanto
Published: December 2022

Plastic waste in Indonesia has an impact that has caused high levels of environmental pollution. The use of plastic in everyday life as a packaging continues to increase, causing plastic waste to increase day by day. Plastic waste derived from petroleum raw materials is difficult to decompose by microbes in the soil. Biodegradable plastics are plastics that can be degraded by microorganisms and are made from renewable materials. Research on the use of biodegradable plastic synthesis has been developed because it is environmentally friendly and renewable. Biodegradable plastic is an alternative material to replace conventional plastic packaging so as not to pollute the environment. Biodegradable plastic is made with natural polymers as the main ingredient so that it is easily digested by microorganisms. Corn starch is a waste from corn processing used by the food industry. The starch content in corn starch can be used to make biodegradable plastic. In this study, biodegradable plastic was synthesized from corn starch with chitosan and calcium silicate as filler and then glycerol as a plasticizer. The purpose of this study was to determine the variation of filler on the results of biodegradable plastics made.  The characteristics of biodegradable  were  marked  by  the  presence  of  Tensile Strength, Elongation and Biodegradibility tests according to SNI Standards. The highest Tensile Strength value was obtained for the Chitosan variation of 2.62 Mpa and for the Calcium Silicate Variation of 2.8 Mpa, then for the Elongation Value for the Chitosan and Calcium Silicate Variations in accordance with SNI standards, which was 10-40% and for the Biodegradability of Chitosan and Calcium Silicate Variations. Calcium Silicate about 35-40 days.
PENGARUH KECEMASAN MATEMATIKA TERHADAP PERSIAPAN TES UTBK SISWA SMAN 1 KEFAMENANU
Authors: Laja Yosepha Patricia Wua , Simarmata Justin Eduardo
Published: December 2022

Math anxiety is a condition that inhibits students' ability to reach the potential of learning experiences and classroom math assessments, or both which are emotional responses and objects of fear or fear. This definition shows that math anxiety can be one of the internal factors felt by each individual, especially when approaching certain tests or exams. UTBK test is one type of test or exam that makes math a compulsory subject that is tested. Students need to be given preparation in the form of guidance to reduce math anxiety in order to get maximum results. The purpose of this study is to see if there is an influence between math anxiety on UTBK test preparation of SMAN 1 Kefamenanu students. The method used in this research is descriptive quantitative. The population of this study were all students of SMAN 1 Kefamenanu Class XII. While sampling was done randomly totaling 71 students. The results showed that there was a negative relationship between math anxiety and UTBK test preparation results (simulation). However, this relationship does not have a significant effect on the result of UTBK test preparation
ANALISIS KEMAMPUAN PEMECAHAN MASALAH MATEMATIS PADA SOAL SETARA INSTRUMEN TIMSS UNTUK SISWA SMP NEGERI 1 MASOHI
Authors: Hikmawati Andi , Laurens Theresia , Wattimanela Henry J
Published: December 2022

Mathematical problem solving ability is one of the abilities that must be mastered by students in order to be able to mathematically solve problems often found in real life. The purpose of this study was to describe students' mathematical problem solving abilities on the volume of cubes and blocks equivalent to the TIMSS instrument. The research subjects are five students of class IX science at SMP Negeri 1 Masohi who were selected based on the category of problem solving ability. This type of research is a qualitative descriptive research supported by quantitative data. The data obtained from this study is data on mathematical problem solving ability tests such as written tests and interviews. The results show that students with very high abilities are able to interpret problems well, interpret strategies and problem-solving steps accaording to the plan, and consistently check back. Students with high abilities are able to apply the four steps in solving ploblems even though there are some questions that students make mistakes in setting strategies and substituting scores at the completion stage. Students with moderate abilities sometimes make mistakes in setting a strategy, make calculation errors, and do not check back to the maximum so that they get inaccurate results. Meanwhile students with low abilities unable to meet the completeness of the stage of understand the problem is writing down the things that are known and asked. As for students with low abilities cannot solve problems completely because of poor planning. Making mistakes in calculations and not checking again so that they do not get the right results
Uşak Kent Merkezinde Bir Açık Alan Rekreasyon Kaynağı Olarak Bazı Orman İçi Dinlenme Yerlerinin Mevcut Rekreasyon Potansiyellerinin Gülez Yöntemi İle Değerlendirilmesi
Authors: AK Duygu
Published: December 2022

Bu çalışmada Uşak kent merkezinde bir açık alan rekreasyon kaynağı olarak orman içi dinlenme (mesire) yerlerinin mevcut rekreasyon potansiyellerinin değerlendirilmesi amaçlanmış ve bu amaçla Gülez’in geliştirmiş olduğu “Açıkhava Rekreasyon Potansiyelinin Saptanması” yöntemi uygulanmıştır. Bu yerler arasında halk tarafından en fazla bilinen ve ziyaret edilenler seçilmiştir. İncelenen rekreasyon alanlarının mevcut potansiyelleri Akse Çamlığı (%58), Huzurpark (%65), Korupark (%56) ile sırasıyla orta, yüksek ve orta olarak bulgulanmıştır. İncelenen alanlar içinde Huzurpark’ın en yüksek; Korupark’ın ise en düşük rekreasyon potansiyeline sahip olduğu tespit edilmiştir. Gülez (1990) yöntemini oluşturan formülde en fazla ağırlığa sahip olan unsurlar, peyzaj değeri ve ulaşılabilirliktir. Söz konusu bu iki unsurun, bir alanın rekreasyon potansiyelini etkileyen en önemli unsurlar olduğu tespiti, bu çalışma sonuçları ile doğrulanmıştır. Çünkü incelenen alanlar içinde yalnızca Huzurpark’ın yüksek rekreasyon potansiyeline sahip olmasını ve diğer alanlardan daha fazla puan almasını sağlayan unsurlar, “peyzaj değeri” ve “ulaşılabilirlik” olmuştur.
Otel İşletmeciliğinde Yalın İlkelerin 14001:2015 Çevre Yönetim Sistemine Entegrasyonu
Authors: KAPUCUGİL İKİZ Aysun , ABACI Ezel
Published: December 2022

Bu çalışma da Turizm alt çalışma dallarından olan Kıyı Turizmi örneklemiyle ISO 14001:2015 Çevre Yönetim Sisteminin Yalın Sistem anlayışıyla ilişkisi incelenmiştir. Çalışma; Turizm, Çevre Yönetim Sistemi ve Yalın Yönetim Sistemi olarak üç bileşen üzerine yürütülmüştür. Yalın Yönetim sisteminin ISO 14001:2015 Çevre Yönetim Sistemiyle olan ilişkisinde birbirleri arasındaki paralellikten yola çıkılmıştır. Yalın uygulama araçlarını standardın hangi madde ve gerekliliklerinde kullanılabileceği organizasyona nasıl entegre olabileceği ilişkilendirilmeye çalışılmıştır.
Pengembangan Media Interaktif Berbasis Android Berbantuan Ispring dan Website 2 APK Builder pada Materi Aritmatika Sosial
Authors: Safira Dede Vika Tsania , Marliani Dinda Sintia , Nasihah Dida Durotun , Nurmaulidiyah Novita , Mubarok Jajat Fajril , Ratnaningsih Nani
Published: December 2022

Salah satu bagian penting dalam pembelajaran adalah penggunaan media pembelajaran. Pemahaman ide oleh siswa dapat ditingkatkan melalui penggunaan media interaktif yang tepat. Karena portabel dan lebih mudah digunakan, Android menjadi alat pembelajaran yang baik. Dengan menggunakan I-Spring dan APK Builder, penelitian ini  mempunyai tujuan untuk membuat bahan ajar interaktif berbasis Android untuk materi aritmatika sosial kelas VII. Eksplorasi ini merupakan penelitian dengan menggunakan teknik pengembangan model Borg and Gall Procedural yang dimodifikasi dengan tahapan analisis kebutuhan, desain, validasi desain, revisi desain, uji coba produk, revisi produk dan produk akhir. SMP Negeri SATAP 3 Sodonghilir menjadi tempat penelitian ini. Temuan penelitian menunjukkan bahwa media interaktif yang dihasilkan dapat digunakan untuk mengajarkan materi Aritmatika Sosial.
ANALISIS PERAN SEKTOR PERTANIAN TERHADAP PERTUMBUHAN PEREKONOMIAN WILAYAH
Authors: Dewi Erina Yuliana , Yuliani Eppy , Rahman Boby
Published: December 2022

Pertumbuhan ekonomi suatu wilayah bergantung kepada permintaan dari luar wilayah terhadap produk-produk dari dalam wilayah itu sendiri, sehingga sektor/komoditi yang memiliki keunggulan komparatif dapat mendorong pertumbuhan ekonomi bagi wilayah terkait. Guna menunjang pembangunan suatu wilayah, maka diperlukan identifikasi komoditas-komoditas unggulan pertanian sebagai arahan prioritasi pengembangan yang menjadi dasar perumusan strategi pembangunan wilayah. Tujuan dari kajian ini yaitu guna mengetahui peran sektor pertanian dalam pertumbuhan perekonomian wilayah. Kajian ini menggunakan metode kualitatif deskriptif dengan pendekatan literatur studi guna memberi penjelasan mengenai peran sektor pertanian terhadap perekonomian wilayah. Keberadaan sektor pertanian dalam pembangunan perekonomian masih dianggap sebagai sektor pasif dan sekadar menjadi elemen penunjang sebagai input bagi sektor lain terutama sektor industri serta perdagangan dan jasa. Akan tetapi, hal tersebut juga dapat menjadi peluang serta tantangan bagi sektor pertanian untuk berkembang pesat dan meningkatkan daya saingnya. Meskipun sektor pertanian pada suatu wilayah bukan merupakan sektor unggulan, bukan berarti sektor pertanian dapat dikesampingkan karena perannya yang penting dalam proses pertumbuhan ekonomi dan erat kaitannya dengan ketahanan pangan, serapan tenaga kerja, sumber bahan baku industri, dan sumber pendapatan masyarakat yang kemudian berdampak pada pertumbuhan perekonomian suatu wilayah.
PENGEMBANGAN PARIWISATA BERBASIS EDUECO TOURISM DI KABUPATEN RAJA AMPAT, PAPUA BARAT
Authors: Rasyid Risal , Karmila Mila , Kesaulya Hertine M
Published: December 2022

ABSTRACTThis study aims to examine the concept of tourism development in Raja Ampat Regency. Tourism development is currently important for regions that have tourism potential, because in the last few decades the tourism sector is one sector that plays an important role in improving the country's economy. This study uses a mixed method, qualitative methods are used to identify the condition of tourism objects and formulate the concept of tourism development in accordance with their potential and see policies that support tourism development in Raja Ampat Regency, while the use of quantitative methods to analyze the number of visits and tourist demand using the method least square. The output of this research is the concept of tourism development in Raja Ampat Regency based on EduEco Tourism, this concept means that tourism activities in Raja Ampat focus on ecological concepts, especially on the balance of nature and the environment, and in tourism activities tourists can learn about biodiversity and tourism ecosystems in Raja Ampat.Keywords: Tourism, Raja Ampat, Tourism Concept ABSTRAKPenelitian ini bertujuan untuk mengkaji konsep pengembangan pariwisata di Kabupaten Raja Ampat. Pengembangan pariwisata saat ini penting dilakukan oleh daerah-daerah yang memiliki potensi wisata, karena dibeberapa dekade terakhir sektor pariwisata merupakan salah satu sektor yang memiliki peran penting terhadap peningkatan ekonomi negara. Penelitian ini menggunakan metode campuran kualitatif dan kuantitaif, metode kualitatif digunakan dalam mengidentifikasi kondisi obyek wisata dan merumuskan konsep pengembangan pariwisata sesuai dengan potensi yang dimiliki serta melihat kebijakan yang mendukung pengembangan pariwisata di Kabupaten Raja Ampat, sedangkan penggunaan penggunaan kuantitatif untuk menganalisis jumlah kunjungan dan permintaan wisatawan yang menggunakan metode least square. Luaran dari penelitian ini berupa konsep pengembangan pariwisata Kabupaten Raja Ampat yang berbasis EduEco Tourism, konsep ini berarti bahwa kegiatan pariwisata di Kabupaten Raja Ampat menitikberatkan pada konsep ekologis terutama pada keseimbangan alam dan lingkungan, dan dalam kegiatan pariwisata wisatawan dapat memperoleh pembelajaran mengenai keanekaragaman hayati dan ekosistem wisata di Raja Ampat.Kata Kunci: Pariwisata, Raja Ampat, Konsep Pariwisata
Endovascular Closure of Secondary Septal Defect in Children with Low Body Weight
Authors: Ditkivskyy Igor O. , Voloshyn Denys L. , Yermolovych Yuliia V. , Perepeka Iryna A. , Lazoryshynets Vasyl V.
Published: December 2022

The aim. To assess the effectiveness and safety of transcatheter closure of a secondary atrial septal defect (ASD) using an occluder in symptomatic children weighing ≤10 kg.

Materials and methods. In the period from November 2014 to June 2021, on the basis of the National Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine, closure of secondary ASD using an occluder was performed in 18 patients, among them 13 women (72.2%) and 5 men (27.8%). Th e mean age of the patients was 18.94±9.44 months (the youngest patient was 12 months, the oldest was 4 years). The mean weight was 9.294±1.170 kg (6.4 kg to 10 kg), the mean Z-score was -1.7±1.5 (-4.6 to 0.46), the mean height was 80 cm (71 cm to 88 cm). According to the measurements by transesophageal echocardiography (TEE), the average size of the defects was 13.7 mm±3.6mm (the largest 18.0 mm, the smallest 6.0 mm).

Results and discussion. In our publication, the effectiveness of the method was 100% (18/18), while the world statistics show 94-95%. Th e frequency of complications was 5.6% (n=1). We suggest that this is associated with the use of a sizing balloon and careful selection of the device.

When choosing treatment tactics for symptomatic children weighing ≤10 kg, the decisive factor was the determination of the presence of edges and the size of the defect. Defects were considered suitable for closure, according to TEE data, when all margins of the defect were ≥4 mm, except for the aortic margin. Although the total length of the interatrial membrane was taken into account, it was not of decisive importance, since for most occluders with the presence of all edges, the fields of the implant could not interfere with the work of the anatomical structures of the heart. To determine the real size of the defect, we recommend a measuring balloon under TEE control.

The following devices were used to close the defect: MemoPart ASD occluder, Amplatzer Septal Occluder, LifeTech HeartR Occluder, LifeTech HeartR Multi-Fenestrated Atrial Septal Defect (MF-ASD) Occluder.

 

Conclusion. After the study, we are convinced that the endovascular method of closing a hemodynamically significant secondary ASD for the treatment of children with a body weight of ≤10 kg has proven to be an effective method, with successful implantation of the occluder in 100% of cases.
Extracranial Carotid Artery Aneurysms: 20-Year Experience of Surgical Management
Authors: Kobza Ihor I. , Mota Yuliya S. , Kobza Taras I.
Published: December 2022

Extracranial carotid artery aneurysm (ECAA) is a rare vascularpathology with reported incidence of 0.2-5.0% of all carotid artery surgical interventions. Most of ECAAs remain clinically asymptomatic, however, they can manifest in neurological symptoms as transient ischemic attack or stroke. The presence of a pulsating formation, swallowing disorders, signs of compression of cranial nerves may beindicative of the aneurysm growth, which is associated with higher risk of thromboembolic complications and less oftenwith rupture. Surgical treatment is a method of choice in symptomatic patients or in cases of the aneurysm growth and includes resection with arterial reconstruction, ligation of the artery or endovascular intervention.

The aim. To improve the results of surgical treatment of ECAAs.

Materials and methods. The results of clinical examination, laboratory, instrumental, intraoperative observations were analyzed in 39 patients (35 [89.7%] men and 4 [10.3%] women) with 44 ECAAs, who were admitted to the Vascular Surgery Department of Lviv Regional Clinical Hospital for the period from 2003 to 2022. To conϐirm the diagnosis of ECAA, preoperative instrumental examination included duplex ultrasonography and multispiral computed tomography angiography.

Results. Etiological causes of ECAAs included: atherosclerosis (79.5%),ϐibromuscular dysplasia (7.7%), trauma (5.1%), previous operations in the neck region (5.1%) and infection (2.6%). The justiϐication of the choice of surgical tactics depended on the localization of aneurysm, concomitant carotid occlusive disease or pathological deviation of carotid arteries. Early results of surgical treatment were evaluated up to 30 days of the postoperative period. The postoperative complications included: transient ischemic attack in 1 (2.6%), ischemic stroke in 2 (5.1%), cranial nerve damages in 4 (10.3%), thrombosis of arterial reconstruction in 2 (5.1%), hematoma of postoperative wound in 4 (10.3%), infection of postoperative wound in 1 (2.6%) cases. Postoperative mortality was 2.6%.

Conclusion. ECAA is a rare clinical disease that requires an active surgical approach to reduce the risk of ischemic stroke. Reconstructive surgery of ECAAs is a highly effective method of treatment that allows to achieve satisfactory results and prevent the development of severe complications.
Fabry Disease, a Rare Disorder with Cardiac Manifestations. The Problem of Diagnosis and Treatment: a Literature Review
Authors: Rudenko Kostiantyn V. , Nevmerzhytska Lidiia O. , Unitska Olha M. , Danchenko Polina A. , Leiko Nadiia S.
Published: December 2022

Fabry disease (FD) is an X-linked lysosomal storage disease caused by a mutation in the gene encoding α-galactosidase A and leads to reduced activity or complete absence of this enzyme, which causes the accumulation of globotriaosylceramide (Gb3) and its deacylated form (lyso-Gb3) in cells of the whole body. FD can occur both with multisystem manifestations, including damage to the nervous system, kidneys, and skin, and can affect only the heart. Cardiac involvement is a major cause of poor quality of life and death in patients with FD and an underrecognized cause of heart failure with preserved ejection fraction and ventricular arrhythmias in men over 30 years of age and women over 40 years of age. Cardiac damage begins at an early age, progresses subclinically until the appearance of significant symptoms, and usually manifests as leftventricular hypertrophy, mimicking hypertrophic cardiomyopathy.

After the introduction of enzyme replacement therapy, early recognition of FD and differential diagnosis with other causes of leftventricular hypertrophy have become crucial to limit the progression of the disease. Recent advances in the understanding of cardiac pathophysiology and imaging have improved diagnostic and therapeutic approaches to the cardiac manifestations of this pathology.

Modern achievements in the study of cardiac manifestations of FD have made it possible to significantly improve diagnostic and therapeutic approaches, in particular, in relation to the identification of pathogenetic mechanisms of organ damage and early disruption of their function. A better understanding of secondary pathogenic pathways, such as myocardial inflammation, may influence future therapeutic strategies and timely diagnosis of FD.

Delay in diagnosis and untimely initiation of treatment remain critical problems for many patients with FD, especially for patients with late-onset cardiovascular manifestations, in whom treatment effects may be more limited and ineffective.

Cooperation between specialists in genetic diseases and cardiologists remains important to identify patients before the appearance of cardiac symptoms in order to obtain maximum therapeutic effects.
Comparative Analysis of Early Postoperative Period in Patients with Total Arterial Revascularization and Conventional Coronary Artery Bypass Grafting
Authors: Rudenko Nadiya M. , Pukas Oleksandr Yu.
Published: December 2022

The use of total arterial myocardial revascularization in patients with multivessel lesions of the coronary arteries has a number of advantages, namely the duration of functioning or patency of the grafts. The level of total arterial myocardial revascularization implementation in developed and developing countries remains quite low.

The aim. Based on the analysis of our own experience, to determine the influence of the technique of total arterial revascularization on the frequency of complications in the early postoperative period.

Materials and methods. From February 22, 2016 to December 24, 2020, 390 consecutive patients were operated at the Ukrainian Children’s Cardiac Center. The patients were divided into two groups: participants of the group I underwent total arterial myocardial revascularization, and those includedin the group II underwent conventional coronary artery bypass grafting (CABG). The inclusion criteria were: ischemic heart disease, stable angina or exertional angina, multivascular coronary artery disease, absence of valvular pathology.

Results. There was zero 30-day mortality in both groups. The frequency of postoperative bleeding was higher in group II and amounted to 1.6%. Surgical wound complications (infection) were also more common in the group II: 1.2% versus 0.69% (p=0.906) in the group I. Similarly, laboratory parameters such as the level of creatine kinase-MB were almost identical.

Conclusions. Total arterial myocardial revascularization is a safe method with good immediate results. The frequency of complications in total arterial myocardial revascularizationdoes not differ from that in conventional CABG. For a wider application of the total arterial myocardial revascularization,it is necessary to continue toconduct studies of the remote postoperative period.
Utilization potential of borogypsum and silica fume in producing lightweight building material
Authors: ÖZTÜRK Çetin
Published: December 2022

The present study is aimed at investigating the utilization of two crucial industrial wastes, borogypsum and silica fume, as the main raw materials in the production of building materials. For this aim, different receipts were designed from boron waste (borogypsum) belonging to Emet Boric Acid factory (Kütahya/Turkey) and silica fume, which was taken from Electrometallurgy facilities (Antalya/Turkey). Mixtures were prepared so that the amount of waste material used in the composition was 90%, and the remaining 10% was binder clay. The samples were prepared with different proportions of both wastes were pressed uniaxially at 10 MPa, and the shaped samples were then fired at 1000, 1050, 1100, and 1150 °C. Physical and mechanical tests, as well as mineralogical and microstructural analyses, were carried out on the fired samples. The technical properties of the samples derived from the wastes were evaluated depending on the type of waste material and its usage amounts, and firing temperatures. It has been understood that the use of high Borogypsum will cause high firing loss, which will negatively affect the dimensional stability of the material. Moreover, with silica fume addition to borogypsum, the water absorption and porosity values increased, and the strength values decreased accordingly. Consequently, the water absorption and bending strength values obtained in the samples prepared from a mixture of 70% borogypsum and 20% silica fume can be considered the usage as a wall tile is possible since they coincide with the technical properties defined in the EN ISO 10545-3 and EN ISO 10545-4 standards, respectively.
Academic libraries and research data management
Authors: Boté-Vericad Juan-José , Healy Sharon
Published: December 2022

Purpose. Open Science entails research reproducibility, with an emphasis on data sharing and reuse. Hence, research data management (RDM) is an essential asset in research institutions for supporting open science. This study oﬀers a systematic review of the landscape of research data management in academic libraries. It further examines the inﬂuence academic libraries can have if they are involved in the research lifecycle process, and how this beneﬁts research institutions that have started implementing research data management, especially in the data-intensive disciplines.
Methodology. In this study, the authors analysed Web of Science and Scopus databases, searching for papers connecting research data management and academic libraries. The authors found a total of N=387 articles. After removing duplicates and applying the exclusion and inclusion criteria process, the authors ﬁnally analysed N=32 articles, n=20 case studies, and n=12 research papers at both national and international levels.
Limitations. This study has some limitations. Although the authors retrieved as many papers as possible for the analysis, it should not be considered as an exhaustive analysis, as varying studies may also be missing from the sample. The authors observed that there are more case studies focused on one institution rather than research papers involving diﬀerent institutions at the international or national level. Therefore, more research studies would enrich the literature and show best practices in RDM.
Results. The results show that research data management has some services implemented in diﬀerent countries at the local or the international level. The authors argue that research data management generates new opportunities for academic libraries and librarians to acquire new skills as a part of the research data lifecycle.
Originality/value. This study reports the current state of research data management at the international level in academic libraries and the inﬂuence libraries can have if they are involved in the research lifecycle process.
Percepcija i stavovi preddiplomskih studenata informacijskih znanosti u Hrvatskoj prema digitalnom obrazovanju u vrijeme pandemije bolesti COVID-19
Authors: Feldvari Kristina , Mičunović Milijana , Gašo Gordana
Published: December 2022

Cilj. Cilj je ovoga istraživanja ispitati percepciju, mišljenja i iskustva studenata preddiplomskog studija informacijskih znanosti o različitim aspektima digitalnog obrazovanja i online nastave tijekom pandemije bolesti COVID-19.
Pristup/metodologija/dizajn. U ožujku i svibnju 2022. godine provedene su tri fokus grupe sa studentima preddiplomskih studija informacijskih (i komunikacijskih) znanosti na trima hrvatskim sveučilištima (N = 18). Nakon transkripcije audiozapisa, provedena je sadržajna analiza rezultata.
Rezultati. Pandemija bolesti COVID-19 znatno je ubrzala digitalnu transformaciju visokoškolskog obrazovnog sustava. Disruptivne promjene i ad hoc prelazak na online nastavu i učenje na daljinu imali su značajan utjecaj na studentsku populaciju. Ispitanici su se većinom brzo i uspješno prilagodili uvjetima rada i učenja u pandemiji. Nasta va je u većini slučajeva uspješno organizirana i održana, a gotovo svi ispitanici imali su osiguran pristup potrebnim digitalnim obrazovnim sadržajima. Unatoč prednostima digitalnog obrazovanja i online nastave, ispitanici su s vremenom osjetili manjak motivacije, pad koncentracije, stres zbog povećanog broja radnih zadataka i online provjere znanja te brigu zbog cjelokupne situacije. Najčešći izazovi odnosili su se na organizaciju i provođenje pismenih ispita i drugih oblika provjere znanja, probleme tehničke prirode, probleme prostorne i vremenske organizacije, manjak osobnog kontakta i nedovoljno razvijen sustav institucijske podrške. Za unaprjeđenje digitalnog obrazovanja i online nastave u mogućim budućim kriznim situacijama ispitanici predlažu osiguravanje videozapisa predavanja, osiguravanje odgovarajuće opreme studentima slabijeg socioekonomskog statusa, veći broj asinkronih nastavnih aktivnosti, smanjenje broja grupnih aktivnosti te bolju organizaciju ustanove u pogledu odabira digitalnih alata za rad, učenje i komunikaciju.
Originalnost/vrijednost. Rad pruža dublji uvid u politiku i praksu digitalnog obrazovanja tijekom pandemije bolesti COVID-19 sa stajališta studenata te tako doprinosi jačanju njihove aktivne uloge u sustavu visokog obrazovanja i kreiranju obrazovne politike. Također, uz pitanje digitalne tehnologije i digitalnih vještina i kompetencija, rad je usmjeren i na mnoge druge aspekte digitalnog obrazovanja, poput organizacije nastavnog procesa, omogućavanja pristupa digitalnim obrazovnim sadržajima, osiguravanja sustava podrške i dr. Rezultati ove kvalitativne studije mogu koristiti kreatorima politika, donositeljima odluka i dionicima sustava visokog obrazovanja kako bi osigurali održivost i kvalitetu ekosustava digitalnog obrazovanja u Hrvatskoj, općenito i u mogućim budućim kriznim situacijama.
Vrednovanje slikovnog sadržaja u povijesnim novinama na primjeru Jastrebarskih novina
Authors: Štefanac Tamara
Published: December 2022

Cilj. Ciljevi rada jesu prikazati moguće postupke vrednovanja slikovnog sadržaja  u novinama i razmotriti njegove načine opisa i preformatiranja u suvremenoj praksi baštinskih ustanova.
Metodologija. Istraživanje je provedeno na uzorku Jastrebarskih novina (1964.– 1991.) i to kroz analizu povijesnog i suvremenog konteksta izlaženja i korištenja novina te kvantitativnu i kvalitativnu analizu sadržaja.
Rezultati. Slikovni prilozi u novinama i elementi njihovog graﬁčkog oblikovanja sadržajno su važni i često su neodjeljivi od tekstualnih priloga. Društveno-politički kontekst i propagandni diskurs slikovnih priloga u Jastrebarskim novinama od manjeg je značaja u odnosu na njihovu važnost kao izvora za bolje razumijevanje povijesti zavičaja i lokalne svakodnevice. Prilikom preformatiranja novina u kojima su slikovni prilozi vrednovani kao značajni, potrebno je uzeti u obzir njihove vizualne elemente.
Originalnost. Ovim radom potvrđena je nužnost vrednovanja pojedinačnog naslova novina u njihovom povijesnom i suvremenom kontekstu te iz aspekta slikovnog sadržaja. Također se preispituju odgovarajuće metode preformatiranja i zalaže se za induktivan i analitički pristup prilikom prenošenja svih oblika sadržaja na druge medije. Prema trenutnim spoznajama, ovaj rad prvi put donosi sadržajnu analizu slikovnih priloga utemeljenu u kontekstualnoj analizi lokalnih novina te prikazanu kroz prizmu politika vrednovanja i praksi preformatiranja slikovnog sadržaja.
Traumatic hallux sesamoid fracture: a case report
Authors: Demasi Quadros de Macedo Gustavo , Saori Gushiken Erika , De Oliveira Gabriel Hernandes , Vasconcelos de Castro Larissa , Farias Molina Wellington
Published: December 2022

The authors describe an extremely rare case of traumatic fracture of both hallux sesamoid bones, which was treated non-surgically, and the indications, contraindications, and unfavorable outcomes analyzed. Level of Evidence V; Therapeutic Studies; Expert Opinion.
Forefoot width correction in patients with hallux valgus after rotational scarf osteotomy
Authors: Mombello Zuleta Franco , Butteri Ana Ines , Chaparro Ravazzano Felipe , Pellegrini Pucci Manuel , Carcuro Urresti Giovanni , Ortiz Mateluna Cristian
Published: December 2022

Objective: Our objective was to compare foot width (bony and soft tissues) in radiological images pre- vs. post-corrective scarf osteotomy in patients with hallux valgus. Methods: We retrospectively performed measurements of forefoot width (both bony diameter and total diameter including soft tissues) on anterior posterior standard radiographs of 30 patients, totaling 42 feet, pre- and postoperatively, at three months. These measurements were performed by two evaluators and their reliability was calculated. Results: Radiologically, preoperative mean of the 1-5 metatarsal bony width was 89.30mm (SD ± 5.8), reduced to 80.42mm postoperatively (SD ± 3.5; p<0.001). Regarding the soft tissue width, preoperative mean was 102.45mm (SD ± 6.4) and postoperative, 98.3mm (SD ± 5.1; p<0.001). The interclass correlation coefficient between both observers was excellent in most measurements (range, 0.884-0.973). Conclusion: We report an objective reduction in forefoot width, in both bony and soft tissue diameter, finding means of 8.88 mm (10%) and 4.12mm (4.1%), respectively, after scarf-Akin osteotomy. Level of Evidence IV; Case Series.
Posterior femoral hemiepiphysiodesis for genu recurvatum with equinus foot deformity: a novel surgical proposal
Authors: Botter Montenegro Nei , Oliveira Generoso Talissa , Ramalho Júnior Amancio
Published: December 2022

Genu recurvatum is characterized as an hyperextension deformity of the knee in the sagittal plane and can be associated to structured equinus deformity of the ankle and foot. Amongst its causes are conditions like arthrogryposis, cerebral palsy, tibial tuberosity arrest, poliomyelitis and syndromes with generalized ligamentous hyperlaxity. The treatment of this condition can be challenging, specially when associated with equinus of the foot and, to date, aggressive methods such as femur or tibia osteotomies are the most used for its correction. We describe here a safe and minimally invasive technique with posterior hemiepiphysiodesis of the distal femur performed with transphyseal screws for correction of the genu recurvatum with apex on the distal femur associated with rigid equinus of the foot due to tarsal coalition. This technique has great potential for correcting the recurvate knee in the immature skeleton and can be an excellent alternative to the more aggressive methods currently used for the treatment of this deformity. Level of Evidence V; Therapeutic Studies; Expert Opinion.
Three-dimensional assessment of hallux valgus correction using the Lapicotton technique
Authors: Jasper Ryan , Mallavarapu Vineel , Stebral Hannah , Jones Matthew , VandeLune Christian , Schmidt Eli , Talaski Grayson , Fayed Aly , Alencar Mendes de Carvalho Kepler , Chun Kim Ki , Barbachan Mansur Nacime Salomão , Dibbern Kevin , De César Netto César
Published: December 2022

Objective: The objective of the study was to assess the efficacy of the LapiCotton procedure on patients with hallux valgus (HV) combined with medial longitudinal arch collapse. Methods: Preoperative and postoperative weight-bearing computed tomography (WBCT) scans were obtained from patients with HV submitted to the LapiCotton procedure. Semi-automatic measurements were applied to 22 WBCT images across 11 patients enrolled in the study using a software package (Bonelogic, Disior™, Helsinki, Finland). Significance level was set at 0.05. Results: The hallux valgus angle (HVA) was significantly larger (p=0.026) in the preoperative group (Mdn = 27.52) than in the postoperative group (Mdn = 20). In addition, the Meary sagittal measurement was found to be significantly increased (p=0.033) in the preoperative group (Mdn = -14.28) when compared to the postoperative group (Mdn = -11.15). It was also observed that the intermetatarsal angle was significantly larger (p=0.003) in the preoperative group (Mdn = 15.68) compared to the postoperative group (Mdn = 11.26). Conclusion: The LapiCotton procedure effectively corrected radiographic parameters in patients with HV combined with the medial longitudinal arch collapse. Level of Evidence III; Therapeutic Studies; Comparative Retrospective Study.