bluuebunny/crossref_metadata_2025 huggingface dataset:
High rates of anorectal chlamydia in women: a cross-sectional study in general practice
Authors: AB Elisabeth , Luijt Dirk , Ott Alewijn , Dekker Janny H
Published: March 2022

Background

Genital and anorectal Chlamydia trachomatis (CT) frequently present together in sexually transmitted infection (STI) clinics.

Aim

To investigate the prevalence of co-occurrent genital and anorectal chlamydia infection, and to study whether sexual behaviour is associated with anorectal infection.

Design & setting

A cross-sectional study in general practices in the north of the Netherlands.

Method

Women attending general practice with an indication for genital chlamydia testing were included and asked to complete a structured questionnaire on sexual behaviour. Anorectal infection prevalence was compared according to testing indications: standard versus experimental (based on questionnaire answers). Variables associated with anorectal chlamydia were analysed by univariate and multivariate logistic regression analyses.

Results

Data could be analysed for 497 of 515 women included. Overall, 17.8% (n = 87/490) were positive for CT; of these, 72.4% (n = 63/87) had co-occurrent genital and anorectal infection, 13.8% (n = 12/87) had genital infection only, and 12.6% (n = 11/87) had anorectal infection only. Rectal infection was missed in 69.3% of cases using the standard indication alone, while adding the sexual history still missed 20.0%. Age was the only variable significantly associated with anorectal infection.

Conclusion

The prevalence of anorectal disease is high among women who visit their GP with an indication for genital CT testing. Many anorectal infections are missed despite taking comprehensive sexual histories, meaning that standard treatment of genital infection with azithromycin may result in rectal persistence. Performing anorectal testing in all women with an indication for genital CT testing is, therefore, recommended.
PERLINDUNGAN HUKUM TERHADAP KONSUMEN APARTEMEN TERKAIT HAK ATAS TANAH BERSAMA
Authors: Mayasari Diah Kartika , Riyanto Slamet , Fadillah Syarif
Published: March 2022

Diah Kartika Mayasari, 1220140030. Flats are built as an effort to meet the need for housing, especially in the city and supporting areas around it which are increasingly difficult to meet due to the high rate of population increase while the land area does not increase. With increasingly affordable prices, strategic location and complete facilities of the apartment becomes its own attraction for the community. But in practice in the field, many consumers who buy apartments without knowing the status of ownership of the land where the apartment stands. If the status of the land is SHM atan HGB Murni then there is no problem, The problem that may arise is if the status of the land is HGM above the Management Thing (HPL), if HGB has matured and the government or third party as the landowner does not want to extend the HGB, then it is entitled to take back the land. The purpose of this study is to find out how to regulate land rights related to land with apartments, how the practice of providing information by developers to prospective consumers regarding land rights with apartments and how legal protection of apartment consumers in disputes over shared land rights. The research method used is an empirical juridical method. The data collected is information relevant to the topic or problem that will or is being researched. Information can be obtained from books, research reports, scientific essays, theses, regulations, provisions and written sources both printed and electronic. In addition, data is also obtained from interviews with several developers and consumers of the apartment. The results showed that the majority of developers did not inform prospective consumers about the status of the land to be built unless asked by consumers. This led to allegations that developers could be hiding something that could one day harm consumers. The legal protection of consumer flats has been regulated in the Flats Act, so it does not use the Consumer Protection Act. Some provisions in it impose obligations to sellers (legal entities) to meet technical, administrative and civil requirements with the threat of administrative, civil or criminal sanctions.
Tinjauan Yuridis Pengaruh Eksploitasi Anak terhadap Tingkat Kesejahteraan Anak Ditinjau dari UU No. 35 Tahun 2014 tentang Perubahan Atas UU No. 23 Tahun 2002 tentang Perlindungan Anak (Studi Kasus Putusan Nomor :623/Pid.Sus/2016/PN.Mlg)
Authors: Saputro Nugroho Doni , Firdaus Dailami , Mamang Damrah
Published: March 2022

Skripsi ini membahas bagaimana dampak dari tindakan eksploitasi anak dan bagaimana dampaknya terhadap tingkat kesejahteraan anak. Skripsi ini dilatarbelakangi oleh masih banyaknya anak di bawah umur yang berkeliaran di jalanan mengamen, mengemis, menjual barang dan lain sebagainya, hal ini dilatarbelakangi karena orang tua yang tidak terlalu memperdulikan perbuatannya yang menyuruh atau membiarkan anak-anaknya bekerja di jalanan karena suatu alasan. Rumusan masalah dalam skripsi ini adalah tentang bagaimana faktor penyebab terjadinya tindakan eksploitasi anak dan bagaimana dampaknya terhadap kesejahteraan anak, serta bagaimana pengaturan perlindungan anak di Indonesia. Jenis penelitian ini adalah penelitian hukum yuridis normatif dan didukung oleh penelitian yuridis empiris. Jenis dan sumber data menggunakan data primer, sekunder dan tersier. Teknik pengumpulan data adalah studi pustaka ditambah wawancara untuk melengkapi data. Teknik analisis data menggunakan metode analisis kualitatif. Hasil penelitian ini menjelaskan bahwa suatu tindakan eksploitasi didasarkan pada berbagai faktor yang meliputi faktor ekonomi, faktor lingkungan dan faktor sosial. Kesimpulan dalam skripsi ini salah satu faktor terkuat yang mendorong terjadinya eksploitasi adalah faktor ekonomi, karena lemahnya keadaan ekonomi keluarga dapat menyebabkan orang tua mengabaikan segala cara dalam mengumpulkan pundi-pundi rupiah untuk pemenuhan kebutuhan sehari-hari, termasuk menyuruh atau mengizinkan anak. ke jalan untuk membantu menghasilkan uang. Hal ini berdampak sangat buruk terhadap tingkat kesejahteraan anak, pemenuhan hak-hak anak yang tidak lengkap, pergaulan yang bebas dan tidak terkendali, perubahan-perubahan pada anak.
Perlindungan Konsumen Muslim terhadap Produk Pangan Daging Non Kemasan melalui Jaminan Produk Halal
Authors: Nurani Intan , Zakky Moh , Lubis Efridani
Published: March 2022

Related to the validity of non-packaged meat food products, Law No. 8 of 1999 on Consumer Protection only stipulates that business actors are prohibited from producing and/or trading goods and/or services that do not follow the provisions of halal production, as stated "halal" contained in the label. Regarding the necessity of halal information in non-packaged meat food products, it can be seen in Law No. 33 of 2014 on Halal Product Guarantee, which includes "products" in the Halal Products Act are goods and / or services related to food, beverages, drugs, cosmetics, chemical products, biological products, genetic engineering products, and used goods used, used, or utilized by the community. While what is meant by halal products is products that have been declared halal in accordance with Islamic sharia. The Halal Product Law has clearly stipulated that products entered, circulated, and traded in the territory of Indonesia must be halal certified. So basically, if the product sold is halal, then it must be halal certified. Consumer protection law today gets quite attention because it concerns the rules for the welfare of society, not only the community as consumers who get protection, but business actors also have the same right to protection, each has rights and obligations. The government plays a role in regulating, supervising, and controlling so as to create a conducive system that is related to each other, thus the goal of the welfare of society at large can be achieved. In healthy business activities there is a balance of legal protections between consumers and producers.

The absence of balanced protection causes consumers to be in a weaker position even if the product produced by the manufacturer is a limited type of product, it will certainly harm the consumer. Haram food has been detailed in the Quran, while halal food is not explained, which is why in Indonesia it is regulated about halal certification with the aim that the interests of consumers can be protected.
Analisis Hukum terhadap Penetapan Kuasa Asuh Anak sebagai Akibat Perceraian (Analisa Hukum Pasal 156 Kompilasi Hukum Islam)
Authors: Maryanih Maryanih , Akram Andi , Fadillah Syarif
Published: March 2022

Divorce has legal consequences, such the distribution of marital property, and child custody. In the Compilation of Islamic Law, child custody must be seen from the child condition, where in the provisions of Article 105, it is known that child custody must see whether the condition of mummayiz or not. For children who are not yet mummayiz, the custody of the child is given priority to the biological mother, but it is not uncommon where in divorce cases, the child is not yet mummayiz, the custody rights are delegated to his biological father, so the purpopse in this study, is intended to examine and analyzing the position of child custody due to legal divorce consequences according to the Compilation of Islamic Law and who has the right of child custody due to legal consequences of divorce. This study uses a normative research method, with the data used is secondary in the form of library data. The results of the study indicate that the position of parents in child custody due to the legal consequences of divorce according to the Compilation of Islamic Law, is based on Article 105 and Article 156 of the Compilation of Islamic Law, where the hadhanah of the child, the biological mother is preferred, but if there are certain conditions based on Article 156 of the Compilation Islamic law, where the hadhanah holder cannot guarantee the physical and spiritual safety of the child, of course the child's hadhanah can be transferred.
Konsep Hukum Biodiversitas dalam Dunia Digital (Fondasi Teoritik Pengembangan Hukum Lingkungan Indonesia Berbasis Biodiversitas)
Authors: Lubis Efridani
Published: March 2022

Biodiversity protection in Indonesia becomes an urge considering that the number of it is numerous since Indonesia categorized as one mega-biodiversity countries in the world. Biodiversity protection in Indonesia is still based on international system which is political approach. While biodiversity conservation needs all aspects to support the conservation. One of the proposal in the term of the conservation is introducing Biodiversity Law as part of education system for legal profession. Developing existing Environment Law lead to the possibility of Biodiversity Law since the two subject has similar system. The difference is Biodiversity Law focus on protection and utilization of biodiversity in general term including genetic resources as a clear and structured protection instrument so that explore and exploit the biodiversity could be done with full responsibility for assurance to next generation beneficial. However, this will take several steps, and the first step is inserting the subject to Environment Law as material course for law students in Indonesia.
Efektifitas Pelaksanaan Penundaan Kewajiban Pembayaran Utang (PKPU) dalam Mencegah Kepailitan (Studi Pengadilan Niaga pada Pengadilan Negeri Jakarta Pusat)
Authors: Rifani Ratu Alawiyyah , Fauziah Fauziah , Fahruddin Muhammad
Published: March 2022

The results showed that the Postponement of Debt Payment Obligations or PKPU means that it can be used by debtors to avoid bankruptcy. So before declared as bankruptcy, debtors can apply for PKPU. PKPU applications are submitted to the Commerrcial Court established within the General Court. In 2017, 2018 and 2019 the Commercial Court at Central Jakarta District Court has received many incoming PKPU case reports and continues to increase every year. PKPU that has been accepted and determined can be submitted as a peace plan by the debtor, the peace plan is submitted to resolve debt settlement disputes between debtors and creditors, PKPU can be considered effective if PKPU submitted by the debtor ends with peace. In addition, the driving factor for PKPU's effectiveness in preventing bankruptcy is the content of the peace agreement that has been homologated by the Commercial Court.
Ten-Hour Stable Noninvasive Brain-Computer Interface Realized by Semidry Hydrogel-Based Electrodes
Authors: Liu Junchen , Lin Sen , Li Wenzheng , Zhao Yanzhen , Liu Dingkun , He Zhaofeng , Wang Dong , Lei Ming , Hong Bo , Wu Hui
Published: March 2022

Noninvasive brain-computer interface (BCI) has been extensively studied from many aspects in the past decade. In order to broaden the practical applications of BCI technique, it is essential to develop electrodes for electroencephalogram (EEG) collection with advanced characteristics such as high conductivity, long-term effectiveness, and biocompatibility. In this study, we developed a silver-nanowire/PVA hydrogel/melamine sponge (AgPHMS) semidry EEG electrode for long-lasting monitoring of EEG signal. Benefiting from the water storage capacity of PVA hydrogel, the electrolyte solution can be continuously released to the scalp-electrode interface during used. The electrolyte solution can infiltrate the stratum corneum and reduce the scalp-electrode impedance to 10 kΩ-15 kΩ. The flexible structure enables the electrode with mechanical stability, increases the wearing comfort, and reduces the scalp-electrode gap to reduce contact impedance. As a result, a long-term BCI application based on measurements of motion-onset visual evoked potentials (mVEPs) shows that the 3-hour BCI accuracy of the new electrode (77% to 100%) is approximately the same as that of conventional electrodes supported by a conductive gel during the first hour. Furthermore, the BCI system based on the new electrode can retain low contact impedance for 10 hours on scalp, which greatly improved the ability of BCI technique.
Tailoring Defects in Hard Carbon Anode towards Enhanced Na Storage Performance
Authors: Dong Ruiqi , Wu Feng , Bai Ying , Li Qinghao , Yu Xiqian , Li Yu , Ni Qiao , Wu Chuan
Published: March 2022

Hard carbon (HC) anodes show conspicuously commercialized potential for sodium-ion batteries (SIBs) due to their cost-effectiveness and satisfactory performance. However, the development of hard carbon anodes in SIBs is still hindered by low initial Coulombic efficiency (ICE) and insufficient cyclic stability, which are induced by inappropriate defects in the structure. Herein, we introduce a simple but effective method to tailor the defects in HC by the chemically preadsorbed K
+
. The soft X-ray absorption spectroscopy at the C K-edges reveals that K
+
can anchor on the hard carbon via C-O-K bonds, occupying the irreversible reactive sites of Na
+
. Therefore, the irreversible capacity caused by some C-O bonds can be reduced. Moreover, the preadsorbed K
+
can induce the rearrangement of carbon layers and lead to a high graphitization structure with fewer defects and large interlayer spacing, which not only improves the structural stability and electrical conductivity of the HC anode but also facilitates fast Na
+
diffusion. Therefore, the as-obtained optimized anode demonstrates a higher ICE with better cyclic stability and superior rate capacities compared with the anode without preadsorbed K
+
. This work indicates that K
+
preadsorbed into hard carbon is a practicable alternative to enhance the Na storage performances of HC anodes for SIBs.
ĐẶC ĐIỂM PHÂN BỐ VÀ HIỆN TRẠNG NGUỒN GEN CÂY TRÚC ĐEN (PHYLLOSTACHYS NIGRA LODD.MUNRO) TẠI HÀ GIANG VÀ LÀO CAI
Authors: Quân Trần Công , Hà Đặng Thị Thu , Trung Nguyễn Văn
Published: March 2022

Cây Trúc đen có tên khoa học Phyllostachys nigra Lodd. Munro thuộc họ Hòa thảo (Poaceae). Trúc đen là loài hiếm, số lượng cây ít, vùng phân bố hẹp, mới được phát hiện ở Việt Nam trong một số năm gần đây. Với mục tiêu nghiên cứu về đặc điểm phân bố và hiện trạng của cây Trúc đen; các phương pháp chuyên gia, phương pháp PRA và điều tra thực địa được áp dụng để xác định vùng phân bố và hiện trạng của Trúc đen ở hai tỉnh Hà Giang và Lào Cai. Kết quả nghiên cứu cho thấy Trúc đen chỉ phân bố ở vị trí chân và sườn núi đất hoặc núi đất xen đá, độ cao trên 1.000 m so với mực nước biển. Tỉnh Lào Cai có 03 khu phân bố: Xã Dền Thàng, huyện Bát Xát ở 03 hộ gia đình; Bản Khoang (xã Ngũ Chỉ Sơn) 02 hộ; xã Tả Van 02 hộ, thị xã Sa Pa. Tỉnh Hà Giang có 02 khu phân bố: Thị trấn Đồng Văn có 02 hộ; xã Tả Lủng 05 hộ, huyện Mèo Vạc. Hiện trạng cây Trúc đen được trồng ở vườn rừng của các hộ gia đình, với diện tích 98 – 350 m2; số lượng từ 40 – 250 cây/hộ. Như vậy, Trúc đen phân bố ở 05 khu vực, với diện tích và số lượng còn rất ít, nghiên cứu bảo tồn và phát triển là rất cần thiết.
NGHIÊN CỨU QUÁ TRÌNH GIẢI PHÓNG CURCUMIN TỪ NANG MICRO TRONG MÔI TRƯỜNG IN VITRO
Authors: Hùng Nguyễn Đức , Tân Từ Quang , Thủy Vũ Thị Thu
Published: March 2022

Pectin có nguồn gốc tự nhiên, giá thành rẻ, không gây độc, độ ổn định cao, được sử dụng phổ biến trong chế tạo hệ mang thuốc nhằm tăng hiệu quả và giảm số lần sử dụng thuốc. Trong nghiên cứu trước, nang micro curcumin được bào chế thành công bằng công nghệ tạo gel ion, kết hợp sử dụng low methoxyl amidated pectin làm hệ mang thuốc, chất hoạt động bề mặt Solutol® HS 15 và ion Ca²+. Nghiên cứu này tiếp tục tiến hành đánh giá quá trình giải phóng curcumin từ nang micro trong môi trường in vitro nhằm đánh giá hiệu quả bảo vệ nang micro khỏi môi trường acid và quá trình giải phóng có kiểm soát curcumin từ nang micro trong môi trường kiềm. Kết quả nghiên cứu cho thấy, nang micro curcumin không hòa tan trong môi trường pH = 1,2. Ngược lại, trong môi trường có pH = 7,4, nang micro S10 và S15 có hàm lượng curcumin được giải phóng đạt giá trị cao nhất trong 100 phút đầu và sau đó bị kiểm soát giải phóng. Quá trình giải phóng curcumin từ các nang micro trong môi trường có pH = 7,4 tuân theo mô hình Korsmeyer-Peppas. Sự khuếch tán của curcumin từ nang micro vào môi trường giải phóng theo dạng kết hợp giữa khuếch tán phụ thuộc vào nồng độ của dung môi theo định luật Fick và khuếch tán phụ thuộc vào sự giãn nở polymer.
ĐẶC ĐIỂM HÌNH THÁI, NUÔI CẤY VÀ HÀM LƯỢNG DINH DƯỠNG CỦA NẤM LIM XANH (Ganoderma lucidum Lim xanh) THU THẬP TẠI TỈNH LẠNG SƠN
Authors: Hiền Đỗ Thị , Hưng Hoàng Văn , Duệ Đỗ Bích , Tuấn Nguyễn Mạnh
Published: March 2022

Nghiên cứu được triển khai nhằm thu thập và bảo tồn nguồn gen nấm Lim xanh (Ganoderma lucidum) từ tự nhiên. Quả thể nấm Lim xanh thu thập tại rừng tự nhiên thuộc xã Hữu Lân, huyện Lộc Bình, tỉnh Lạng Sơn. Kết quả nghiên cứu cho thấy, sử dụng ethanol 70% trong 7 phút cho hiệu quả phân lập hệ sợi thuần khiết cao nhất từ quả thể nấm, với 26,67% số mẫu thành công. Phân tích trình tự gen ITS 1 – 5,8S rRNA – ITS 2 cho thấy, chủng nấm Lim xanh là thành viên của chi Ganoderma và được đặt tên là Ganoderma lucidum Lim xanh. Chủng nấm Lim xanh có khả năng sinh trưởng trên cả 4 môi trường bao gồm PDA, MCM, YMA, PL; trong đó môi trường PDA là thích hợp nhất cho nấm Lim xanh sinh trưởng. Quả thể nấm Lim xanh nuôi trồng nhân tạo có dạng hình quạt, màu nâu sẫm, đường kính quả thể dao động từ 5-8 cm, cuống nấm dài 7-10 cm và trọng lượng quả thể khô 5,43 - 10,64g. Kết quả phân tích hàm lượng dinh dưỡng của nấm Lim xanh có chứa protein tổng số chiếm 15,46%, carbohydrate (41,42%), xơ (37,70%) và khoáng chất (2,45%).
Laryngeal Cancer Incidence Trends in the Republic of Belarus in 2000–2019
Authors: Колядич Ж.В.
Published: March 2022

За последнее десятилетие отмечается тенденция к росту показателей заболеваемости и смертности среди пациентов с раком гортани. В Республике Беларусь у мужчин РГ стойко занимает 1-е место среди новообразований головы и шеи (за исключением рака кожи). В структуре мужской онкопатологии в разные годы рак данной локализации занимал 8–9-е место, составляя от 2,5 до 3,6%. При этом рак гортани наиболее часто, в 50–60% случаев, поражает лиц трудоспособного возраста (40–59 лет). Несмотря на большое количество публикаций, по-священных диагностике РГ, вопросы своевременной и ранней диагностики предопухолевых заболеваний и РГ до настоящего времени остаются актуальными. В статье представлены данные о динамике грубых интенсивных показателей заболеваемости, стандартизованных показателей заболеваемости злокачественными новообразованиями гортани, сопоставление заболеваемости раком гортани в Беларуси с аналогичными показателями в странах и регионах ближнего и дальнего зарубежья.

The past decade has demonstrated the tendency towards increased incidence and mortality rates in laryngeal cancer (LC) patients. In the Republic of Belarus, LC takes the 1st place among head and neck neoplasms (excluding skin cancer). In the structure of male oncopathology in different years, cancer of this localization took the 8–9th place, ranging from 2.5 to 3.6%. Moreover, LC affects individuals of employable age (40–59 years) more frequently (in 50–60% of cases). Despite the great number of publications dedicated to LC diagnosis, the issues of timely and early diagnosis of premalignancies and LC are still the most relevant. The paper presents the data on the dynamics of rough intensive rates, standardized rates of the incidence of laryngeal malignant neoplasms, as well as the comparison of laryngeal cancer incidence in Belarus with similar indices in other countries.
Desmoid Fibromatosis of Nasal Cavity and Paranasal Sinuses. Description of the Clinical Case
Authors: Хоров О.Г. , Никита Е.И. , Загоровская О.В. , Новиков А.Г. , Нечипоренко А.С.
Published: March 2022

Десмоидная фиброма (агрессивный фиброматоз) является редкой доброкачественной фибробластической опухолью, характеризующейся агрессивным локальным ростом, частым рецидивированием, отсутствием способности к метастазированию. В зависимости от локализации подразделяется на интра- и экстраабдоминальные. В числе последних десмоиды области головы и шеи составляют 7–15% (у взрослых) и крайне редко встречается в полости носа и околоносовых пазух. Единой общепринятой тактики лечения пациентов с десмоидными фибромами не разработано ввиду редкости патологии и отсутствия обобщенных ретроспективных исследований для сравнения различных вариантов лечения. На сегодняшний день используются хирургическое лечение, лучевая терапия, химиотерапия, гормонотерапия, иммунотерапия и их комбинации. Частота рецидивирования после хирургического лечения составляет 27–72%.В данной статье нами описан случай пациентки С. с новообразованием полости носа и околоносовых пазух, ранее диагностированным как хронический полипозный синусит. Новообразование распространялось из полости носа в верхнечелюстную пазуху, решетчатый лабиринт, лобную пазуху слева и левую глазницу. После проведения хирургического лечения были получены результаты гистологического заключения: десмоидная фиброма.

Desmoid fibromatosis (aggressive fibromatosis) is a rare benign fibroblastic tumor characterized by aggressive local growth, frequent relapse, and lack of ability to metastasize. Depending on the localization, it is divided into intra-abdominal and extra-abdominal. Among the latter, desmoidsof the head and neck region appear in 7–15% of patients (in adults), and they are extremely rare in the nasal cavity and paranasal sinuses. A single generally accepted treatment strategy for patients with desmoid fibromas has not been developed due to the rarity of the pathology and the lack of generalized retrospective studies to compare different treatment options. Nowadays, surgical treatment, radiation therapy, chemotherapy, hormone therapy, immunotherapy, and their combinations are used. The recurrence rate after surgical treatment is 27–72%. We described the case of patient S. with a neoplasm of the nasal cavity and paranasal sinuses, previously diagnosed as chronic polyposis sinusitis. The neoplasm spread from the nasal cavity to the maxillary sinus, ethmoid labyrinth, frontal sinus on the left, and left orbit. After radical surgical treatment, the results of histological study were obtained: it was desmoid fibroma.
Assessment of Cognitive Functions in Children with Epilepsy and Prolonged Spike-Wave Activity during Slow Wave Sleep
Authors: Козырева И.В. , Куликова С.Л. , Лихачев С.А. , Белая С.А. , Свинковская Т.В. , Савченко М.А. , Зайцев И.И.
Published: March 2022

Введение. Одной из причин когнитивных и поведенческих нарушений у детей является продолженная спайк-волновая активность в фазу медленного сна (CSWS).Цель. Выбор методов оценки когнитивных функций у детей с эпилепсией и CSWS. Материалы и методы. По результатам анализа существующих методик выбрана методика Ж.М. Глозман, которая включает общую характеристику ребенка, исследование праксиса, гнозиса, речи, памяти и интеллекта. Методика позволяет провести как качественную, так и количественную оценку когнитивных функций у детей разного возраста.Результаты. Приведен пример исследования когнитивных функций по методике Ж.М. Глозман у ребенка 5 лет с фокальной эпилепсией и CSWS. Тестирование когнитивных функций показало, что у пациента до терапии имелись выраженные нарушения всех сфер высших корковых функций, но с преимущественным нарушением праксиса правой руки, орального праксиса и фонематического слуха, что коррелировало с диффузной CSWS высокого индекса с амплитудным преобладанием в теменно-височной области слева. На фоне лечения произошло улучшение более чем на 50% в поведении и речи. Низкий процент динамики в сфере гнозиса – 12% и праксиса (за счет орального праксиса) – 40% коррелирует с данными ЭЭГ после лечения.Заключение. Методика Ж.М. Глозман может применяться как для оценки когнитивных функций у детей с эпилепсией и CSWS, так и для оценки динамики в ходе лечения.

Introduction. Continued spike wave activity during slow wave sleep (CSWS) is one of the causes of cognitive and behavioral impairment in children.Purpose. Choice of the methods for assessing cognitive functions in children with epilepsy and CSWS.Materials and methods. After analysis of the existing techniques, J.M. Glozman technique was selected, which includes the general characteristics of the child, the study of praxis, gnosis, speech, memory and intelligence. The technique lets to conduct both qualitative and quantitative assessment of cognitive functions in children of different ages.Results. An example of the study of cognitive functions with the method of Zh.M. Glozman in a 5-year-old child with focal epilepsy and CSWS was presented. Testing of cognitive functions showed that the patient had pronounced impairments in all areas of higher cortical functions before therapy, but with a predominant impairment of the right hand praxis, oral praxis, and phonemic hearing, which correlated with diffuse CSWS of a high index with amplitude predominance in the parietotemporal region on the left. During treatment, there was an improvement of more than 50% in behavior and speech. A low percentage of dynamics in the field of gnosis – 12% and praxis (due to oral praxis) – 40% correlates with EEG data after treatment.Conclusion. Zh.M. Glozman technique can be used to assess cognitive functions in children with epilepsy and CSWS and to assess the dynamics during treatment.
Oral Anticoagulants Use in Patients on Hemodialysis
Authors: Рапецкая Н.В. , Комиссаров К.С. , Калачик О.В.
Published: March 2022

Показаниями к назначению антикоагулянтной терапии являются профилактика инфаркта мозга, системной тромбоэмболии при фибрилляции предсердий и тромбозе глубоких вен, которые встречаются у пациентов с терминальной стадией хронической болезни почек (ХБП) чаще, чем в общей популяции. Пациенты на гемодиализе не были включены ни в одно исследование по предупреждению инфаркта мозга и лечению венозных тромбозов, следовательно, возможное преимущество использования новых оральных антикоагулянтов (НОАК) у этой группы пациентов не выявлено. В статье описан опыт применения дабигатрана и ривароксабана у диализных пациентов.

Prevention of stroke and systemic thromboembolism in atrial fibrillation and deep vein thrombosis, that occur in patients with end-stage kidney disease more often than in general population, are indications for anticoagulant therapy use. Patients on hemodialysis were not included in any trials on stroke prevention and treatment of venous thromboembolism and have therefore not profited from the introduction of direct oral anticoagulants. The experience of dabigatran and rivaroxaban use in patients on hemodialysis is described in the article.
Melanotic Neuroectodermal Tumor in Children. Literature Review and Description of the Clinical Case
Authors: Корсак А.К. , Клецкий С.К. , Тимофеев А.Ю.
Published: March 2022

Меланотическая нейроэктодермальная опухоль (МНЭО) – редкое новообразование, диагностируемое у детей в возрасте до одного года, имеющее, как правило, доброкачественный характер. Обладая прогрессирующим ростом, инфильтрирующим разрушением подлежащих тканей, она вызывает анатомические и функциональные нарушения в челюстно-лицевой области. С учетом описанных случаев ее злокачественных форм, меланотическая нейроэктодермальная опухоль требует своевременной диагностики и срочного хирургического лечения. Авторами представлены обзор литературы и описание клинического случая диагностики и лечения ребенка женского пола 5 месяцев с МНЭО верхней челюсти.Ранняя диагностика опухоли и своевременное хирургическое вмешательство (выскабливание опухоли с фрезерованием подлежащей кости) позволили значительно сократить объем оперативного вмешательства с хорошим отдаленным (один год) результатом. Для верификации опухоли необходимо использовать гистологический и иммуногистохимический методы исследования. Детям с МНЭО после оперативного лечения показано диспансерное наблюдение в течение 2–3 лет для исключения рецидива заболевания или его своевременного выявления.

Melanotic neuroectodermal tumor (MNEO) is a rare neoplasm diagnosed in children under the age of one year, which is usually benign. Possessing progressive growth, infiltrating destruction of the underlying tissues, it causes anatomical and functional disorders in the maxillofacial region. Taking into account the described cases of its malignant forms, melanotic neuroectodermal tumor requires timely diagnosis and urgent surgical treatment. The authors provide a review of literature and a description of the clinical case of the diagnosis and treatment of a female child of 5 months old with MNEO of the upper jaw.Early diagnosis of the tumor and timely surgical intervention (curettage of the tumor with milling of theunderlyingbone) significantly reduced the volume of surgical intervention with a good long-term (one year) result. To verify the tumor, it is necessary to use histological and immunohistochemical methods of research. After surgical treatment, children with MNEO should undergo dispensary observation for 2–3 years to exclude a relapse of the disease or its timely detection.
Advancing gender equality and closing the gender digital gap: Three principles to support behavioural change policy and intervention
Authors: David Raluca
Published: March 2022

Worldwide, interventions and policies to improve gender equality or close gender gaps often struggle to reach their targets. For example, women lag considerably behind in use of even simple digital technologies such as mobile phones or the internet. In 2020, the gap in mobile internet use in low- and middle-income countries was at 15%, while in South Asian and Sub-Saharan African countries, it remained as high as 36% and 37% respectively (GSMA, 2021). Use of the internet for more complex activities shows an even wider gap. In Cairo, in 2018, only 21% of female internet users gained economically, and only 7% were able to voice their opinions online (with similar statistics for India, Indonesia, Kenya, Uganda and Colombia, Sambuli et al., 2018). This is despite the fact that empowering women through digital technologies is central to global gender equality strategies (e.g. Sustainable Development Goals, United Nations, 2015), and is believed to facilitate economic growth and industry-level transformation (International Monetary Fund, 2020). Progress is slow because behaviours are gendered: there are stark dissociations between what women and men do – or are expected to do. These dissociations are deeply entrenched by social norms, to the extent that interventions to change them face resistance or can even backfire. Increasingly, governments are using behavioural change interventions in a bid to improve public policy outcomes, while development or gender organisations are using behavioural change programmes to shift gender norms. However, very little is known about how gendered social norms impact the digital divide, or how to use behavioural interventions to shift these norms. Drawing on several research papers that look at the gender digital gap, this brief examines why behavioural change is difficult, and how it could be implemented more effectively. This brief is addressed to policymakers, programme co-ordinators in development organisations, and strategy planners in gender equality interventions who are interested in ways to accelerate progress on gender equality, and close the gender digital gap. The brief offers a set of principles on which to base interventions, programmes and strategies to change gendered behaviours. The principles in this brief were developed as part of a programme of research into ways to close the gender digital gap.
Automatic speech recognition and text-to-speech technologies for L2 pronunciation improvement
Authors: Gottardi William , Almeida Janaina Fernanda de , Tumolo Celso Henrique Soufen
Published: March 2022

This paper presents a reflection on two technologies – automatic speech recognition (ASR) and Text-to-Speech (TTS) – to improve learners’ pronunciation, aiming for successful spoken communication. It sheds some light on the practical usage of these technologies, demonstrating their effectiveness, qualities, and limitations to assist teachers in deciding the most efficient digital resources applied to their students’ needs. A review of literature on previous empirical studies was carried out, with quantitative and/or qualitative studies conducted by researchers in the field, investigating teachers’ and learners' perceptions and the use of ASR and TTS as a pedagogical tool for pronunciation practice. As a result, it was concluded that a) the presented resources seem to have the potential to enhance pronunciation practice, both in terms of perception and production; b) technology can result in considerable benefits to learners, mainly as a supplement to pronunciation teaching; and c) the use of these digital resources is a way of giving learners the opportunity to focus on their specific difficulties and receive personalized feedback while becoming more autonomous in their learning process.
Kepadatan Populasi Cacing Tanah pada Perkebunan Kelapa Sawit di Desa Salang Tungir Kecamatan Namorambe
Authors: Purba Jhon Kevin , Sitinjak Rama R , Agustina Nur Ariyani , Irni Julaili
Published: March 2022

Penelitian ini bertujuan untuk menganalisis kepadatan populasi cacing tanah di perkebunan kelapa sawit dengan perbedaannya pada strata umur kelapa sawit di Desa Salang Tungir Kecamatan Namorambe.Metode yang digunakan adalah metode survey dengan teknik pengambilan sampel cacing tanah secara hand sorting pada stasiun I (TBM) dan stasiun II (TM). Analisis data untuk kepadatan hingga indeks nilai penting cacing tanah digunakan rumus tertentu, dan untuk  perbedaan kepadatan digunakan uji T. Hasil penelitian menunjukkan bahwa cacing tanah di perkebunan kelapa sawit TBM terdapat 3 jenis: Pontoscolex corethrurus, Pheretina sp., dan Lumbricus. Kepadatan relatif dan indeks nilai penting yang tertinggi ditemukan pada Pheretina sp. yaitu 36,09% dan 69,42%. Sedangkan pada TMterdapat 4 jenis: Pontoscolex corethrurus, Pheretina sp., Lumbricus, dan Microscolex. Kepadatan relatif dan indeks nilai pentingnya ditemukan pada Pontoscolex corethrurus yaitu secara berurut 30,56% dan 55,63%. Nilai kepadatan cacing tanah ditemukan lebih tinggi pada perkebunan kelapa sawit yang berumur 4 tahun.Kata kunci: Cacing tanah; Elaeis quineensis Jacq; kepadatan Earthworm Population Density in Oil Palm Plantation inSalang Tungir Village, Namorambe District ABSTRACTThis study aims to analyze the population density of earthworms in oil palm plantations with the differences in the age strata of oil palm in Salang Tungir Village, Namorambe District. The method used is survey method with earthworm sampling technique by hand sorting at station I (TBM) and station II (TM). Analysis of data for density to index of significance of earthworms used a certain formula, and for differences in density used the T test. The results showed that there are 3 types of earthworms in TBM oil palm plantations: Pontoscolex corethrurus, Pheretina sp., and Lumbricus. The highest relative density and significant value index were found in Pheretina sp, namely 36.09% and 69.42%, respectively. While in TM there are 4 types: Pontoscolex corethrurus, Pheretina sp., Lumbricus, and Microscolex. The relative density and significance index found in Pontoscolex corethrurus were 30.56% and 55.63%, respectively. Earthworm density values were found to be higher in oil palm plantations aged 4 years.Keywords: Earthworm; Elaeis quineensis Jacq; density
Hubungan asupan makan dan tingkat stres dengan kadar glukosa darah pada pasien diabetes melitus tipe II di masa pandemi Covid-19
Authors: Fariqi M. Zulfikar Al , Yunika Regina Pricilia
Published: March 2022

Latar Belakang: Indonesia merupakan salah satu negara di dunia yang terkena pandemi Covid-19. Orang dengan riwayat penyakit kronis (komorbiditas) lebih mungkin terinfeksi virus Corona. Diabetes tipe II adalah penyakit kronis. Orang yang rentan terkena Covid-19 adalah pasien diabetes tipe II karena memiliki ketahanan tubuh yang lemah, sehingga pasien diabetes tipe II perlu menjaga kadar glukosa darah yang baik untuk mencegah perburukan Covid-19. Hal terpenting dalam mengendalikan diabetes adalah mengendalikan faktor risiko seperti asupan makan dan menjaga tingkat stres. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara kadar glukosa darah dengan asupan makan dan tingkat stres pada pasien diabetes tipe II selama pandemi Covid-19. Metode: Penelitian ini merupakan penelitian deskriptif analitik dengan desain cross sectional. Teknik pengambilan sampel dalam penelitian ini adalah purposive sampling dengan jumlah pasien sebanyak 75 orang. Penelitian dilakukan di Puskesmas Sakra Lombok Timur pada November 2020. Data asupan makan dikumpulkan menggunakan formulir food recall. Data tingkat stres diperoleh dengan kuesioner Depression Anxiety Stress Scales (DASS 42). Glukosa darah diukur menggunakan pengukur glukosa darah. Data diolah dengan uji Chi-Square dengan taraf signifikansi 95% (α=0,05). Hasil: Ada hubungan antara asupan makanan dengan glukosa darah (p=0,012), dan ada hubungan stres dengan kadar glukosa darah (p<0,001). Kesimpulan: Ada hubungan antara asupan makan dan stres dengan kadar glukosa darah pada pasien diabetes tipe II selama pandemi Covid-19.
Crystal orientation dependence of metal–insulator transition for VO2 microwires fabricated on TiO2(110) substrates with step and terrace structures
Authors: Kim Kyungmin , Genchi Shingo , Yamazaki Shiro , Tanaka Hidekazu , Abe Masayuki
Published: March 2022

Vanadium dioxide (VO2) thin films exhibit a metal–insulator transition (MIT) with sensitivity to the lattice strain. Substrates with step and terrace structures are an attractive platform for growing high-quality thin films. Thus, a prominent lattice strain effect could be derived using VO2 thin films on these substrates. In this study, VO2/TiO2 microwires were fabricated following the thin film growth to investigate the microwire-direction dependence of the MIT property. The in-plane crystal orientation dependence of the MIT property was enhanced for VO2/TiO2 microwires with step and terrace structures, which is promising for strain engineering in device applications.
Efektivitas aerobic exercise terhadap status kardiovaskular lansia pada masa pandemi Covid-19
Authors: Hijriana Isni , Sari Nadia
Published: March 2022

Penurunan aktivitas fisik dapat menimbulkan dampak negatif bagi kesehatan. Aktivitas fisik penting ditingkatkan pada lansia karena akan memberikan pengaruh yang positif terhadap berbagai organ tubuh terutama fungsi kardiovaskular. Tujuan penelitian ini adalah untuk mengetahui pengaruh  dari aktivitas fisik  yaitu  aerobic exercise terhadap status kardiovaskular  lansia pada masa pandemi covid-19. Metode penelitian menggunakan desain quasy eksperimental dengan rancangan one group pretest-post test. Pengambilan sampel menggunakan consecutive sampling dengan jumlah sampel sebanyak 40 responden.  Pengumpulan data dilaksanakan pada tanggal 30 Mei sampai dengan 19 Juni 2021. Analisis data menggunakan uji statistik Independent Sample T-test (paired t test). Hasil penelitian menunjukkan sebelum diberikan diberikan intervensi aerobic  exercise  sebagian besar tekanan darah sistol responden berada pada katagori hipertensi derajat 1 yaitu sebanyak 14 responden (35,0 %) dan tekanan darah diastol berada pada katagori hipertensi derajat 1 yaitu sebanyak  14  responden (35,0 %). Setelah diberikan intervensi aerobic  exercise sebagian besar tekanan darah sistol responden berada pada katagori pre hipertensi yaitu sebanyak 19 responden (47,5%), dan  tekanan darah diastol berada pada katagori pre hipertensi yaitu sebanyak 17 responden (42,5 %). Berdasarkan hasil uji paired t-test menunjukkan bahwa terdapat perbedaan sebelum dan setelah diberikan intevensi aerobic exercise terhadap status kardiovaskular (tekanan darah) pada lansia dengan nilai p-value 0,00. Kesimpulan dalam penelitian ini adalah latihan aerobic exercise efektif dalam menjaga fungsi kardiovaskular khususnya stabilitas tekanan darah pada lansia.
Pengembangan Bahan Ajar Tematik Berbasis Kearifan Lokal Guna Meningkatkan Hasil Belajar Kognitif Siswa
Authors: Azizah Lathifatul , Alnashr M Sofyan
Published: March 2022

Tujuan penelitian ini adalah mengembangkan bahan ajar tematik berbasis kearifan lokal wilayah Sragen untuk meningkatkan hasil belajar kognitif siswa. Jenis penelitian yang digunakan adalah penelitian riset dan pengembangan yang mengacu pada model 4-D. Teknik pengumpulan data yang digunakan yaitu observasi, angket, nilai pre-tes dan post-test. Hasil penelitian pengembangan ini berupa bahan ajar tematik berbasis kearifan lokal yang memenuhi kriteria valid dengan hasil validasi ahli materi mencapai 84%, hasil validasi ahli desain 88%, dan hasil validasi ahli pembelajaran 86%. Hasil uji coba kemenarikan bahan ajar tematik berbasis kearifan lokal mencapai 72% dan nilai rata-rata post-test siswa mencapai 90,2%. Hasil uji-t pada perhitungan manual dengan tingkat kemaknaan 0,10 diperoleh hasil thitung > ttabel yaitu 1,288 > 0,691 artinya H0 ditokak dan H1 diterima. Hal ini menunjukkan bahwa produk yang dikembangkan memiliki tingkat efektifitas yang tinggi sehingga layak digunakan dalam pembelajaran dan dapat meningkatkan hasil belajar siswa kelas IV MI Ma’arif Slendro Kabupaten Sragen.
Praktik Baik Manajemen Menuju Usaha Mikro, Kecil dan Menengah (UMKM) Mandiri dan Produktif di Kampung Bulak Timur, Kelurahan Cipayung, Kota Depok, Jawa Barat
Authors:   Universitas Pembangunan Nasional Veteran Jakarta, Mardiatmi Bernadin Dwi , Nopiyanti Anita ,   Universitas Pembangunan Nasional Veteran Jakarta, Resti Anggi Angga ,   Universitas Pembangunan Nasional Veteran Jakarta
Published: March 2022

Abstract Purpose: to provide education to MSME business actors on good management practices in managing and determine MSME management models that can realize good management practices as an effort to improve MSME management performance. This management model contains aspects of company management, namely marketing management, production management, financial management, and human resource management. Method: The method used is to provide education and literacy about good managerial practices. The material provided includes general management and human resources, production management, financial management, and marketing management. In measuring the level of understanding of participants before giving the material and filling out the post-test after the material is given. In addition, questionnaires were filled out to develop participants' understanding of good management practices using analytical indexes. Results: The result of this study is an increase in understanding of management practices as seen from the increase in the average pre-test of 5.56, increasing in the post-test to 7.31. MSMEs actors understand the material provided on general management and human resources, production management, financial management, and marketing management. Based on the index analysis, the participants' level of understanding of the material on human resource management, marketing management, production management, and financial management is in the high category. Conclusions: Educational and literacy activities about good management practices can increase partners' knowledge about aspects of business management and can put this knowledge into practice in business progress.
Pengaruh Budaya Organisasi Terhadap Komitmen Karyawan Pada PT. Telkom Masamba Kabupaten Luwu Utara
Authors: Khaerana Khaerana , Disa Disa
Published: March 2022

Tujuan penelitian ini adalah untuk mengetahui Pengaruh Budaya Organisasi terhadap Komitmen Karyawan pada PT. Telkom Masamba Kabupaten Luwu Utara. Jenis data yang digunakan adalah data kuantitatif dan kualitatif, sementara sumber data yang digunakan adalah data primer dan data sekunder dengan teknik pengumpulan data adalah observasi, wawancara dan kuesioner. Penelitian ini menggunakan metode Analisis Regresi Linear Sederhana. Populasi dalam penelitian ini adalah seluruh karyawan PT. Telkom Masamba sebanyak 35 orang, sementara untuk teknik pengambilan sampelnya adalah teknik sampling jenuh (sensus), dimana seluruh populasi dijadikan sampel, yakni sebanyak 35 responden. Hasil penelitian menunjukkan nilai thitung 4,280 > nilai ttabel 2,034 dengan taraf signifikansi sebesar 0,000 < dari 0,05, serta nilai koefisien regresi budaya organisasi bernilai positif sebesar 0,637, sehingga dapat dimaknai bahwa budaya organisasi berpengaruh positif dan signifikan terhadap komitmen karyawan pada PT. Telkom Masamba Kabupaten Luwu Utara. Sedangkan nilai koefisien determinasi sebesar 33,8%, dan sisanya 66,2% dipengaruhi oleh faktor lain yang tidak diteliti dalam penelitian ini.
Lyapunov’s stability of the unperturbed motion governed bythe
Authors:   Ion Creanga Pedagogical State University, Republic of Moldova, Neagu Natalia , Popa Mihail ,   Institute of Mathematics and Computer Sciences ”V. Andrunachievici”
Published: March 2022

There were obtained the conditions of stability after Lyapunov of the unper-turbed motion for the system S3 (1,3) in the non-critical case. It was constructed the Lyapunov series for the ternary differential system S3 (1,3) of Darboux type in the critical case and determined the conditions of stability of the unperturbed motion governed by this system.
Continuous and Distribution-free Probabilistic Wind Power Forecasting
Authors: Wen Honglin , Pinson Pierre , Ma Jinghuan , Gu Jie , Jin Zhijian
Published: March 2022

We present a data-driven approach for probabilistic wind power forecasting based on conditional normalizing flow~(CNF). In contrast with the existing, this approach is distribution-free (as for non-parametric and quantile-based approaches) and can directly yield continuous probability densities, hence avoiding quantile crossing. It relies on a base distribution and a set of bijective mappings. Both the shape parameters of the base distribution and the bijective mappings are approximated with neural networks. Spline-based conditional normalizing flow is considered owing to its universal approximation capability. Over the training phase, the model sequentially maps input examples onto samples of base distribution, where parameters are estimated through maximum likelihood. To issue probabilistic forecasts, one eventually map samples of the base distribution into samples of a desired distribution. Case studies based on open datasets validate the effectiveness of the proposed model, and allows us to discuss its advantages and caveats with respect to the state of the art. Code will be released upon publication.