bluuebunny/crossref_metadata_2025 huggingface dataset:
Scientific Fact and Artistic Image: Deformation of the subject field of Ukrainian theater studies in the 1920s
Authors: Klekovkin Olexander
Published: July 2024

The limits of professional activity are determined by the circle of persons who carry it out (who), the content of the activity (production, processing or any other actions aimed at changing the object), quality criteria, technical, ethical and other norms, forms of incentives and sanctions, etc. So, for a formal or informal small or medium-sized social group, the activity of which is inseparable of the situation in which it is carried out, because, in addition to production, it involves the organization of demand and sales, communication with the world external to the group, which leads to stratification activity itself into smaller independent functions (differentiation of production, sales, etc.) and to its transformation, sometimes almost to the point of self-destruction. The heart of professional activity — its subject field or subject matter — is determined not only by the subject of production, its quality criteria and boundaries but also by invisible communications, which are very often hidden from the direct consumer, among which a key role is played by a professional network (structured professional communication carried out by members of the group regarding the subject of production) and its reference library (theoretical works, technical instructions, protocols regulating activities, etc.). During the 1920s, when in Ukraine the self-reliance of activities aimed at the production of scientific facts, therefore, new and preferably practically oriented knowledge about the theater, and the separation of this sphere from others, was fixed in terms of theater studies, there was an extremely active process of formation of the subject field, network and reference library of theater studies. A key role in these processes was played (and not only because of his own professional activity but also as a result of his position in the network) theater historian Petro Rulin, in whose activities, precisely from the point of view of the formation and deformation of the subject matter of theatre studies, its main trends of the 1920s are highlighted.
Characteristics of film music functions in the works of Ukrainian composers of the second half of the 20th century
Authors: Qian Tan
Published: July 2024

This article investigates the characteristics of music functions in films from the perspective of their impacts on the development of the cultural and social spaces of the modern world. It highlights the main tasks of film music in the second half of the 20th century, as well as the directions and trends that shaped its evolution. It is argued that these processes were particularly noticeable during this period and stimulated the attention of not only practitioners but also theorists — researchers of screen arts, to explore the functions of film music, its stylistic and genre-specific features, and principles of application in films. The latest trends are examined based on individual examples — works of Ukrainian composers, whose activities were associated with the development of cinema in Ukraine in the second half of the 20th century, which, in our view, has been insufficiently studied. As a result of the research, it has been established that the dominant function of both off-screen and on-screen music in the cinema of Ukraine during the second half of the 20th century is to complement the video sequence and sound, as well as to enhance the emotional component of the visual image. Among the important principles of using music in this context are consistency in unveiling the main idea of the screen work, the thoughtfulness in intensifying conflict, and harmonizing the overall plot line. The fundamental principles of composer’s creativity, aimed at the appropriate implementation of the music function in the cinema of Ukraine in the second half of the 20th century, have been substantiated. The main functions of music in Ukrainian cinema of the second half of the 20th century, revealed in the activities of composers from this period, have been summarized, allowing us to trace the practical implementation of models for the interaction of music and imagery in films.
Haematolymphoid Tumours Karyotypes: A Moroccan Population Retrospective Study from 1992 to 2021
Authors: Charlène Soro Somda Georgina , Benchikh Sara , Charoute Hicham , El Hamouchi Adil , Aboulfaraj Jamila , Razoki Lunda , Zarouf Latifa , Elbakay Chadli , Rifai Lala Laila , Saile Rachid , Lebrazi Halima , Nassereddine Sanaa
Published: July 2024

Background: Haematolymphoid tumours are a heterogeneous group of pathologies involving cells of the haematopoietic lineage. Data reported here focus on the results of a descriptive, general, exclusive epidemiological study from a Moroccan population.
Objective: Our research aimed to study the distribution of Haematolymphoid tumours in the regional context in Casablanca. Method: We focused on malignancies diagnosed between January 1992 and December 2021 at the Cytogenetics Department of the Pasteur institute of Morocco. Conventional karyotype analysis was performed on bone marrow samples from patients aged between 1 and 95 years and collected data were analyzed to perform statistical analyzes using SPSS20.0 software.
Results: Of the karyotypes investigated 69.8% (1118/1601) were positive for haematolymphoid tumours. The mean age at diagnosis was 42.68 ± 18.20 years. The most frequent pathologies were myeloid neoplasms, with chronic myeloid leukaemia (CML) in first place at 69.8% (780/1118), followed by acute leukaemias (ALL, AML and ALAL) at 21.4% and myelodysplastic neoplasm (MDS) at 5.5%. The most recurrent clonal abnormalities were translocations t (9;22) with 74.2% in CML cases. Deletions 12.5% and additions 8% were found in all diseases with mainly trisomy’s 8 and 21 in AML and MDS and deletions in AML and ALAL. An association was also found in 12 cases of AML between t (8;21) translocation and sexual chromosome deletion (X and Y). The proportion of karyotype’s complexity (9.9%) seems to increase with ages.
Conclusions: Haematolymphoid tumours occur at an earlier age in this cohort. Leukaemia represents the most frequent pathologies with a preponderance of chronic diseases, mainly affecting adults.
Expression of PD-L1 (DAKO 28-8) in Urothelial Carcinoma of Urinary Bladder
Authors: Azmat Henna , Masood Areeba , Sohail Chaudry Summaya , Mushir Syeda Iqra , Khalid Sheikh Ahmareen , Kiran Riaz Syeda
Published: July 2024

Introduction: Around 90% of bladder cancers are urothelial carcinoma. Recent advancements in treatment have shifted towards targeted therapies, particularly immunotherapies targeting PD-L1 (Programmed Cell Death Ligand 1). PD-L1, a ligand for PD-1 receptors, helps cancer cells evade the immune system. Various factors, including genetic alterations, lead to its upregulation in cancer cells. Immunotherapies aim to block this pathway, making cancer cells more susceptible to the immune response.
Objective: The study was designed to assess the frequency of PD-L1 expression by immunohistochemistry in urothelial carcinoma of urinary bladder and its association with histological grades.
Methodology: This study was conducted at Department of Pathology, Pakistan Institute of Medical Sciences Islamabad. Fifty-six cases of urothelial carcinoma were included. Immunohistochemistry using PD-L1 Dako 28-8 clone was applied to prepared tissue sections. PD-L1 positivity was determined by brown membrane staining in tumor cells, scored using the Tumor Proportion Score (TPS).
Results: The median patient age was 63±7 years, with the highest frequency (58.9%) of PD-L1 expression occurring in the age range of 56 to 65 years. However, there was no significant association between PD-L1 expression and age groups. Out of 56 cases, 64.3% had a TPS (Tumor Proportion Score) of ≥5%. Among the 76.7% high-grade cases, 72% had a TPS ≥5%, whereas 28% had a TPS <5%. Among the 23.2% low-grade cases, 61.5% had a TPS <5%, and 38.5% had a TPS ≥5%.
Conclusion: Sixty-four percent urothelial carcinoma cases showed PD-L1 expression. Significant association (p value = 0.02) between PD-L1 expression and high-grade urothelial carcinoma was found using Pearson’s Chi-square test.
Studying the Characteristics of Curcumin-Loaded Liposomal Nanoparticles
Authors: Afyouni Iman , Ghanbarikondori Parizad , Sadeghi Pour Niki , Mir Hashemian Paria , Jalali Fereshtehsadat , Sedighi Armin , Allahyartorkaman Mohammadreza
Published: July 2024

Overview: In this study, the physical and chemical properties of curcumin are extensively examined when it is incorporated into liposome nanoparticles, to enhance its therapeutic potency and bioavailability. Curcumin, a plant-derived polyphenol, has garnered attention for its anti-inflammatory, antioxidant, and anti-cancer activities. However, its clinical utility is hindered by several limitations, including poor water solubility, inadequate absorption, and rapid metabolism. By leveraging the potential of liposome nanoparticles to improve drug delivery and efficacy, this research aims to overcome these obstacles and unlock the full therapeutic potential of curcumin.
Methods: Curcumin-loaded liposome nanoparticles (CLLNs) were fabricated employing a thin-film hydration method, after sonication. The physicochemical attributes of CLLNs were subsequently characterized, encompassing particle size and zeta potential assessment utilizing dynamic light scattering (DLS), encapsulation efficiency (EE%) and drug loading efficiency (DLE%) determination through high-performance liquid chromatography (HPLC), investigation of in vitro drug release patterns in simulated biological fluids.
Results: The CLLNs optimized in this study had a mean particle diameter of less than 250 nm and a negative surface charge, implying good stability and potential for cellular uptake. The encapsulation efficiency and drug loading efficiency were both found to be high, indicating that curcumin was effectively loaded into the liposomes. In vitro release testing showed a sustained release pattern of curcumin from the CLLNs.
Conclusion: The research offered important observations about the advantageous physicochemical features of curcumin-loaded liposome nanoparticles, highlighting their potential as a cutting-edge delivery system for curcumin. The study demonstrated that CLLNs have high encapsulation and drug loading efficiencies, as well as controlled release and improved stability, which suggests their ability to enhance the therapeutic benefits of curcumin. These findings set the stage for future in vivo and clinical trials to fully investigate the potential of CLLNs in medical applications.
Risk Factors for Locoregional Recurrence Following Mastectomy for Localized Breast Cancer in a Nigerian Teaching Hospital
Authors: Olaogun Julius G , Agodirin Olayide S , Dada Samuel A , Akanbi Olusola
Published: July 2024

Background: Mastectomy is an integral part of the management of breast cancer, especially in resource-limited centers. This study aimed to describe the outcomes in terms of locoregional recurrence (LRR) and distant metastasis (DM) after modified radical mastectomy (MRM) for breast cancer and factors associated with them.
Methods: This was a retrospective study of patients who underwent mastectomy between October 2012 and September 2017. Data generated were analyzed using SPSS version 23.0. The results were presented using descriptive statistics. Inferential statistics was done using the chi-square test with statistical significance set at p <0.05.
Results: Sixty-three (88.7%) of 71 patients who had MRM over the study period were eligible. Their ages ranged from 24-80 years with a median of 49 years (IQR, 43-59years). Lump size ranged from 2-18 cm (mean, 7.8±3.5 cm) and the lump duration was 1-48 months (median 6.0, IQR, 4.0-10.0 months). Sixteen (25.4%) patients developed LRR. The interval to occurrence of LRR after mastectomy ranged from 4-36 months (median, 9 months, IQR, 6.0-20.0). Eighteen (28.6%) patients developed distant metastasis 9-60 months after surgery (median 19, IQR 12.0-37.0 months) and 50% of those with LRR were among. Metastasis mostly affected the lungs and pleura in 55.6%. Mean tumour size ≥10cm (p <0.000), mean lump duration >11months, advanced disease T3/4 (p=0.01) and higher number of positive lymph nodes (p=0.011) were significantly associated with LRR. Both tumour size (p=0.01) and positive lymph nodes (p=0.015) are predictors of LRR.
Conclusion: LRR and metastasis are common occurrences after mastectomy. Early presentation and availability of more adjuvant therapies can reduce the rate.
A Review of Literature on Thymoma: An Indolent Tumor of Anterior Mediastimum
Authors: Kumawat Manoj Kumar , Sharma Neeti , Lal Jakhar Shankar , Kumar H. S. , Kumar Rajesh
Published: July 2024

Thymic tumours are a heterogeneous group of malignancies with a range of clinical presentations. The most common types are thymoma and thymic carcinoma, but overall it remains a rare cancer, and one without a clear aetiology. About 50% are diagnosed incidentlly with chest radiography. Thymoma is classified into different stages, which determine the prognosis and type of management. Different types of treatments are available for patients with thymoma. Thymectomy to remove the tumor is the most common treatment of thymoma. We present a case of 20 yr old male presented with shortness of breath, cough, chest pain and fever for past 15 days. Mediastinal widening and modratly pleural effusion in right sided chest seen on chest xray. CECT chest show soft tissue density lesion in anterior and superior mediastinum. FNAC was done that showed feature of thymoma. Biopsy also done that confirmed lymphocytic rich type B thymoma.
The Structure and Function of Oral Cancer Control in Kerala, India: A Narrative Review of Cancer Control Policy Documents from 1988 to 2020
Authors: Philip Phinse M , Kannan Srinivasan
Published: July 2024

The government of Kerala was the first state in India to come out with a comprehensive plan for cancer control based on National Cancer Control Program. The purpose of this review was to identify the structure and function of cancer control in Kerala, India with specific reference to oral cancer. A systematic search was done in PubMed using the keywords “Health Policy”, “Cancer”, “Oral cancer”, “Guiding document” and “Kerala”. All government of Kerala health-related websites were searched electronically for cancer-related policy documents. The medical library catalogs of the two government Comprehensive Cancer Care Centres in the state were searched. All available Government documents, institutional documents, other online resources related to cancer prevention were collected. A checklist was prepared to review the documents. Out of 18 documents identified, two cancer-specific policy documents and two health policy documents were included in the review.The cancer control strategies outlined in the reviewed documents presented a pragmatic vision for cancer control in low-resource settings. The concept called the ‘Kerala Cancer Care Grid’ outlined in one of the documents is a novel strategy to address the geographical inequality in access to cancer care. It recognized interdepartmental coordination and partnership with private sector institutions and community organizations as crucial for achieving comprehensive cancer control. In the reviewed documents, oral cancer was discussed mainly in the context of early detection, health education, and capacity building at the primary care level.
“A Concealed Malignancy” A Case Series on Primary Fallopian Tube Carcinoma
Authors: Sereño Lorene Kate M. , Billod Jimmy A
Published: July 2024

Background: As rare as it is, primary fallopian tube carcinoma presents with a varied range of nonspecific signs and symptoms making its preoperative diagnosis a clinical challenge. It is often missed and is usually recognized later by histopathology. This paper aims to present four cases of fallopian tube cancer managed in our institution in a 5-year period with varied presentation and to discuss updates in diagnosis, management and prognosis in the light of recent literature.
Methods and Results: All of the four cases were of different age group, presented differently and were diagnosed preoperatively to be of another etiology. The first case, 44 year old, initially presented with recurrent vaginal discharge. The patient then presented with supraclavicular nodes to be of metastatic origin. The second case, 58 year old, presented with vaginal spotting and on imaging, a pelvic mass that may represent ovarian new growth. The third and fourth case, 71 and 66 year old respectively, presented with a history of gradually enlarging abdominal mass with an imaging showing an adnexal mass. Intraoperatively, the first and third case revealed a fallopian tube that was thinned out and dilated to a granular and friable tissue. The second case had a right fallopian tube that cannot be grossly identified but an adnexal mass was noted. The fourth case showed a left fallopian tube that was converted to a tan irregular mass. Histopathology revelaed all of these cases as high grade fallopian tube serous carcinoma.
Conclusion: To raise suspicion in the diagnosis of this rare carcinoma preoperatively should be given more importance so that a prompt investigation would be made and catching this disease in an early stage would be achieved. This paper showcased the varied presentation of this disease so as to avoid preoperative misdiagnosis and have a better head start on proper management.
Small Cell Carcinoma of Anal Canal: A Rare Case Report from a Tertiary Cancer Centre
Authors: N V Vinin , Murugavel Hareni , Yahiya Nabeel , Samuel Seena Tresa , Aravind Sithara , Jones Joneetha , Muttath Geetha
Published: July 2024

Extrapulmonary small cell carcinoma (EPSCC) is very rare with an incidence of 0.1 to 0.4% in the United states and the exact incidence in other regions is unknown. Anal canal involvement is extremely rare contributing to < 1% of all EPSCC. Inspite of its rarity, it is of clinical importance due to its aggressive nature. Most of the patients present with lungs and liver metastasis at diagnosis even in early stage tumors. It has a dismal survival rate of 58% at 6-month and 6% at 5-years in contrast to squamous cell carcinoma of anal canal. Exact ethiopathogenesis is unknown. Association with HIV has been seen like squamous cell carcinoma of anal canal. There is very little literature evidence and management is not clear like that of squamous cell carcinoma anal canal. Here we present the case of a 63 year old HIV positive male who presented with small cell carcinoma of anal canal to our institute and the challenges we faced in diagnosis and management.
Solitary Fibrous Tumor of Mediastinum-A Rare Clinical Entity and Review of Literature
Authors: Sahni Manish , Sisodiya Anula , Shah Apurva , Devgarha Sanjeev
Published: July 2024

Solitary fibrous tumour is an uncommon mesenchymal tumour with indolent clinical behaviour as compared to its malignant counterpart. There are very few case reports of extra-pleural malignant SFT arising from the mediastinum.We hereby present a rare case report of solitary fibrous tumor arising from mediastinum and reviewing the literature of this entity.
Perbedaan Pengetahuan Dan Sikap Menyikat Gigi Dengan Youtube Sebagai Media Promosi Kesehatan Di Lahan Basah Siswa SMPN 1 Karang Intan Kabupaten Banjar
Authors: Azizah Aulia , Sari Galuh Dwinta
Published: July 2024

Latar Belakang: Pentingnya kesadaran akan kesehatan gigi dan mulut harus dijaga, sehingga di masa tua kondisinya tetap terjaga dengan baik. Salah satu upaya pemeliharaan kesehatan gigi dan mulut adalah menyikat gigi. Riskesdas 2018 menunjukkan rendahnya proporsi menyikat gigi yang benar. Proporsi penduduk Indonesia menyikat gigi setiap hari sebesar 94,7% tetapi yang menyikat gigi tepat pada waktunya hanya 2,8%. SMPN 1 Karang Intan merupakan sekolah yang berada di Kabupaten Banjar yang berada pada lahan basah yaitu terdapat aliran Sungai Martapura dan belum dilakukan promosi kesehatan gigi dan mulut. Tujuan Penelitian: Menganalisis peningkatan pengetahuan dan sikap menyikat gigi dengan Youtube sebagai media promosi kesehatan siswa SMPN 1 Karang Intan Kabupaten Banjar. Metode Penelitian: Penelitian quasi experiment dengan one-group pretest-posttest design. Sampel penelitian adalah siswa SMPN 1 Karang Intan sebesar 30 orang. Teknik pengambilan sampel adalah total sampling. Pengambilan data menggunakan kuisioner. Hasil: Pengetahuan dan sikap menyikat gigi sebelum promosi kesehatan melalui YouTube terdapat responden dengan kriteria rendah, sedang dan tinggi. Sedangkan setelah promosi kesehatan terdapat kriteria sedang dan tinggi. Uji Wilcoxon menunjukkan terdapat perbedaan pengetahuan dan sikap antara sebelum dan sesudah promosi kesehatan promosi kesehatan gigi dan mulut dengan Youtube sebagai media promosi kesehatan  (Pengetahuan = 0,003 ; Sikap = 0,004). Kesimpulan: Youtube sebagai media promosi kesehatan meningkatkan pengetahuan dan sikap menyikat gigi siswa SMPN 1 Karang Intan Kabupaten Banjar.Kata Kunci: Menyikat Gigi, Pengetahuan, Promosi Kesehatan, Sikap, Youtube
Konsumsi Garam dan efeknya terhadap Hipertensi di Daerah Pasir Gombong Kecamatan Cikarang Utara Kabupaten Bekasi
Authors: Sari Kiki Puspa , Asmi Nur Fauzia
Published: July 2024

Konsumsi garam mempunyai pengaruh positf terhadap terjadinya peningkatan derajat tekanan darah. Garam mengandung natrium yang mempunyai sifat menahan air sehingga menyebabkan volume darah meningkat dan penyempitan pembuluh darah. Tujuan dari penelitian ini yaitu untuk melihat hubungan penggunaan garam terhadap terjadinya resiko hipertensi di Daerah pasir Gombong Kabupaten Bekasi. Metode penelitian yang digunakan yaitu menggunakan cross sectional study dengan 96 responden pada Ibu Rumah Tangga. Variabel yang diambil yaitu karakteristik responden, status hipertensi dan penggunaan garam. Uji hubungan menggunakan chi-square untuk melihat hubungan jumlah garam dan cara penggunaan garam terhadap terjadinya hipertensi.Hasil penelitian menunjukkan bahwa Responden yang menderita hipertensi sebanyak 28 (29.2%). Penggunaan garam pada saat memasak lebih dari satu sendok setiap kali memasak yaitu 60.4%. Responden yang memasukkan garam pada saat Ketika memasak yaitu 83 orang (86.5%). Hasil uji hubungan menunjukkan ρ – Value > 0.005 artinya tidak terdapat hubungan jumlah garam yang dikonsumsi dan cara menggunakan ketika memasak terhadap terjadinya hipertensi.Hipertensi merupakan penyakit yang multifactor, selain dari konsumsi garam yang berlebih hubungan dengan faktor resiko yang lain perlu diteliti.
Gambaran Pasien Pulang Atas Permintaan Sendiri (PAPS) Rawat Inap di RSU Haji Medan Tahun 2022
Authors: Shandy Boy , Ismah Zata , Ismah Zata , Rezha Diandra Kayladifa , Rezha Diandra Kayladifa , Rahmadhani Putri , Rahmadhani Putri
Published: July 2024

Salah satu indikator mutu pelayanan rumah sakit dilihat dari angka kejadian PAPS (Pulang Atas Permintaan Sendiri). PAPS merupakan serangkaian kegiatan proses pemulangan pasien setelah menandatangani surat pernyataan PAPS dan sudah menyelesaikan administrasi. Faktor yang menjadi penyebab terjadinya pulang paksa (PAPS) adalah pengetahuan, keterjangkauan biaya, sarana dan prasarana, sikap petugas, dukungan keluarga pasien, serta persepsi mereka tentang sakit. Dampak dari terjadinya PAPS di rumah sakit menyebabkan menurunnya pendapatan rumah sakit dan dalam jangka panjang dapat menurunkan kinerja rumah sakit. Tujuan penelitian untuk mengetahui Gambaran angka PAPS pada pasien rawat inap di RSU Haji Medan. Metode Penelitian yang digunakan adalah penelitian deskriptif dengan pendekatan cross sectional. Sepanjang tahun 2022, terapat 344 pasien PAPS di RSU Haji Medan, Kategori Usia Pasien PAPS dominasi oleh Manula dan Lansia, Ruangan yang paling banyak Pasien PAPS adalah Jabal Rahmah, dan berdasarkan SMF paling banyak pada SMF penyakit dalam sejumlah 120 pasien.
Analisis Perbedaan Tingkat Kepuasan Pasien Umum dan pasien BPJS pada Pelayanan Rawat Jalan Di Rumah sakit tk. Iii dr. R. Soeharsono Banjarmasin tahun 2022
Authors: Fadhliah Fadhliah , Norfai Norfai , Hadi Zuhrupal , Dhewi Siska , Wirasati Rinie Indah Chandra
Published: July 2024

Berdasarkan data Rumah Sakit TK. III Dr. R. Soeharsono Banjarmasin menunjukkan presentase bulan September hingga bulan Oktober terdapat penurunan hasil kepuasan pasien pada kategori ruang pemeriksaan dokter dalam keadaan bersih dan rapi serta dokter, perawat poli berpenampilan rapih dan ramah dari 98,7% menjadi 97,7%, pada bulan Oktober untuk waktu lama tunggu Rawat Jalan yaitu >60 menit berjumlah 63,9% dan di bulan September untuk waktu lama tunggu Rawat Jalan yaitu >60 menit mencapai 82,2% sehingga melebihi standar yang ditetapkan dari peraturan Menteri Kesehatan tentang bagaimana layanan minum rumah sakit yang menjelaskan lama durasi menunggu rawat jalan maksimal 60 menit. Menganalisis perbedaan tingkat kepuasan pasien umum dan pasien BPJS pada pelayanan rawat jalan di Rumah Sakit TK. III Dr. R. Soeharsono Banjarmasin. Survei analitik dengan pendekatan cross-sectional. Besar sampel terdiri dari 98 pasien umum dan 100 pasien BPJS. Pengambilan sampel menggunakan Accidental Sampling. Uji statistik menggunakan Independent Sampel T test, apabila tidak memenuhi syarat, maka menggunakan uji alternatif yaitu uji Mann-Whitney dengan tingkat kepercayaan 95%. Mayoritas responden dari pasien umum dan pasien BPJS menyatakan puas pada pelayanan rawat jalan di Rumah Sakit TK. III Dr. R. Soeharsono Banjarmasin tahun 2022 yaitu sebanyak 92 pasien umum (93,9%) dan sebanyak 91 pasien BPJS (91%). Berdasarkan hasil uji statistik didapatkan bahwa tidak ada perbedaan rerata tingkat kepuasan pasien umum dan pasien BPJS pada pelayanan rawat jalan di Rumah Sakit TK. III Dr. R. Soeharsono Banjarmasin tahun 2022 (p-value=0,445) > nilai α (0,05). Secara garis besar dapat diartikan bahwa kegiatan operasional Rumah Sakit TK. III Dr. R. Soeharsono Banjarmasin menerapkan pelayanan kesehatan sesuai Standar Operasional Prosedur (SOP) dan dilakukan secara profesional.Kata Kunci: Kepuasan pasien, pasien umum, pasien BPJS.
Faktor-Faktor yang Berhubungan dengan Stunting: Studi Cross-Sectional di Padang Pariaman, Sumatera Barat
Authors: Sari Ira Mulya
Published: July 2024

Stunting menimbulkan tantangan kesehatan masyarakat global, khususnya pada anak-anak di negara-negara berpenghasilan rendah dan menengah. Dampak fisik dan kognitif yang terkait dapat menyebabkan berkurangnya produktivitas dan peningkatan risiko penyakit tidak menular di masa dewasa. Memahami faktor-faktor ini sangat penting untuk menerapkan intervensi yang efektif. Penelitian cross-sectional yang dilakukan di Padang Pariaman, Sumatera Barat ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan stunting pada anak usia 0-59 bulan. Sebanyak 142 responden dari Posyandu dilibatkan, dengan data dikumpulkan melalui pengukuran tinggi badan dan kuesioner yang mencakup demografi, riwayat kesehatan, dan faktor lingkungan. Analisis statistik, termasuk uji Chi-kuadrat, dilakukan untuk mengidentifikasi hubungan. Mayoritas responden berada pada kelompok usia 13-36 bulan, berjenis kelamin laki-laki, dan memiliki ibu dengan pendidikan menengah. Prevalensi stunting sebesar 88,7% dan 9,9% diantaranya mempunyai riwayat penyakit kronis. Komplikasi ibu selama kehamilan, status imunisasi, dan akses terhadap jamban sehat bervariasi di antara responden. Terdapat hubungan yang signifikan antara riwayat penyakit kronis dengan derajat stunting (p-value = 0,001). Severe stunting lebih banyak terjadi pada anak-anak yang mempunyai riwayat penyakit kronis. Penelitian ini menemukan adanya hubungan yang signifikan antara riwayat penyakit kronis pada balita dengan derajat stunting di Padang Pariaman sehingga pentingnya intervensi dan program yang ditargetkan untuk mengurangi prevalensi stunting di wilayah tersebut, dengan fokus pada penanganan riwayat penyakit kronis pada anak usia dini.
Barang Milik Daerah (BMD) : Manajemen Pengelolaan Alat Kesehatan di Kabupaten Barito Utara pada Tahun 2023
Authors: Alam DK Hendy Syahri , Riza Yeni , Ernadi Erwin , Oktaviani Yoneta
Published: July 2024

Pengelolaan alat kesehatan yang efektif termasuk perencanaan kebutuhan, skala prioritas, dan evaluasi manfaat bagi pelayanan kesehatan di Puskesmas. Namun, fokus pada distribusi barang ke Puskesmas dan penghapusan aset yang rusak belum dioptimalkan dalam manajemen BMD di Dinas Kesehatan. Ini berdampak pada ketersediaan dan kualitas layanan di puskesmas, serta membuat perencanaan dan pengadaan alat kesehatan baru lebih sulit. Hal ini yang menjadi latar belakang peneliti untuk melaksanakan penelitian ini yang bertujuan untuk mengetahui manajemen pengelolaan BMD alat – alat kesehatan di Dinas Kesehatan Kabupaten Barito Utara, Penelitian ini menggunakan metode penelitian kualitatif, penelitian kualitatif berupaya untuk memperoleh informasi yang mendalam, adapun responden sebanyak 7 orang informan dengan hasil penelitian terhadap manajemen pengelolaan BMD Alkes di Dinkes Kab. Barito Utara yang sudah sesuai dengan Peraturan Menteri Dalam Negeri Nomor 19 Tahun 2016. Hasil dari wawancara terhadap informan telah di dapatkan beberapa informasi dan data yang menghambat pengelolan BMD di Dinas Kesehatan Kabupaten Barito Utara antara lain, penghapusan alkes di Dinas Kesehatan Kabupaten Barito Utara belum pernah dilaksanakan karena keterbatasan dalam anggaran untuk melaksanakan penghapusan dan alkes tersebut belum bisa dinilai karena belum bisa mendatangkan tim KPKNL Provinsi untuk menilai alkes yang akan dihapuskan, dimana hal ini menyebabkan tidak dapat terlaksananya pengadaan alkes yang sesuai dan dibutuhkan sehingga menyebabkan kurangnya kualitas pelayanan di Puskesmas ke Masyarakat.
Pengaruh Pemahaman Perpajakan, Pemahaman Akuntansi, Pemanfaatan Teknologi Informasi dan Motivasi Terhadap Kepatuhan Wajib Pajak
Authors: Uty Sastya Putri , Kurniawan Harits , Kurniawan Denny , Harto  , Pawiati Suci
Published: July 2024

Dibandingkan dengan sumber penerimaan lain yang digunakan untuk membiayai segala kebutuhan Negara, pajak adalah sumber penerimaan utama Negara. Menurut Undang-Undang Nomor 28 Tahun 2007, sebagaimana telah diubah ketiga kalinya oleh Undang-Undang Nomor 6 Tahun 1983 tentang Ketentuan Umum dan Tata Cara Perpajakan, pajak dikenakan kepada perseorangan atau badan hokum yang mempunyai kewajiban kepada Negara. Studi ini menerapkan metode perantara. Data utama diperoleh secara langsung dari sumber asli tanpa menggunakan media perantra. Data ini diperoleh dari jawaban wajib pajak perusahaan kecil dan menengah (UMKM) yang ada di Kabupaten Lampung Timur. Wajib pajak UMKM menerima kuesioner yang disusun secara sistematis untuk mendapatkan informasi dari wajib pajak yang melaporkan pajak mereka. Pemahaman perpajakan dan akuntansi berpengaruh negatif terhadap kepatuhan wajib pajak UMKM; pemanfaatan TI berpengaruh positif terhadap kepatuhan wajib pajak UMKM; dan motivasi berpengaruh negatif terhadap kepatuhan wajib pajak UMKM. Variabel dependen, kepatuhan Wajib Pajak (Y), dipengaruhi oleh Pemahaman Perpajakan (X1), Pemahaman Akuntansi (X2), Pemanfaatan Teknologi Informasi (X3) dan Motivasi (X4).
Analisis SWOT sebagai Strategi Pengembangan Bisnis dalam Meningkatkan Pendapatan Usaha
Authors: B Indayani , Eni Novitasari  , Dea Wicahya Fitri
Published: July 2024

Penelitian ini dilakukan pada Toko Berlian yang berlokasi di Kota Majene dengan tujuan untuk mengetahui bagaimana penerapan analisis SWOT dalam meningkatkan pendapatan pada Toko Berlian dan mengetahui strategi yang dilakukan oleh Toko Berlian di Kabupaten Majene dalam mempengaruhi pendapatan. Untuk memperoleh informasi tersebut, dilakukan pengumpulan data dengan menggunakan metode wawancara dengan pemilik, karyawan dan pelanggan Toko Berlian. Jenis penelitian yang digunakan dalam penelitian ini adalah deskriptif kualitatif dengan mengolah data kualitatif yang diperoleh dari proses wawancara dan dokumentasi. Hasil penelitian ini menunjukkan bahwa penerapan Analisis SWOT sebagai strategi pengembangan usaha sangat efektif dalam meningkatkan pendapatan usaha di Toko Berlian Kabupaten Majene. Dari penelitian ini, pemahaman yang mendalam mengenai faktor internal seperti kekuatan (seperti kualitas produk dan lokasi yang strategis) dan kelemahan (seperti variasi produk yang terbatas dan kurangnya promosi). Serta, memahami faktor eksternal seperti peluang (peningkatan permintaan pasar dan kemitraan dengan pemasok) dan ancaman (persaingan yang ketat dan kenaikan harga bahan baku).
Complete encasement of the radial nerve by a giant lipoma: illustrative case
Authors: Bah Eugene S , Barone Damiano G , Spinner Robert J
Published: July 2024

BACKGROUND

Among the spectrum of adipose lesions associated with peripheral nerves, complete circumferential encasement of the nerve by the lesion is a very rare entity. The authors report the first case of a giant lipoma that completely and circumferentially encased the radial nerve.

OBSERVATIONS

A 57-year-old woman presented with a large left-arm mass that she had noticed over a year following significant weight loss. She had hypersensitivity and dysesthesias in the left posterior arm but no weakness or other symptoms. Magnetic resonance imaging of the left upper limb demonstrated a large lipoma completely encasing the radial nerve, originating at the level of the spiral grove proximally and extending distally to the lateral epicondyle. The lesion was completely resected at surgery with total preservation of radial nerve function.

LESSONS

Lipomas encasing peripheral nerves can be difficult to manage while preserving function. This case adds to the intriguing spectrum of adipose lesions associated with peripheral nerves.

https://thejns.org/doi/10.3171/CASE24148
Enlarging neurenteric cyst at the craniocervical junction with a fluid-fluid level on magnetic resonance imaging: illustrative case
Authors: Takahashi Toshihide , Yanaka Kiyoyuki , Aiyama Hitoshi , Saura Minami , Kajita Michihide , Takahashi Nobuyuki , Onuma Kuniyuki , Ishikawa Eiichi
Published: July 2024

BACKGROUND

Neurenteric cysts are relatively rare benign congenital intracranial cystic lesions that enlarge rarely and very slowly. The authors present a case of an enlarging neurenteric cyst at the craniocervical junction with a fluid-fluid level on magnetic resonance imaging (MRI).

OBSERVATIONS

A 34-year-old man with no significant medical history underwent head MRI to investigate mild headaches. An incidental cystic lesion, approximately 8 mm in diameter, was revealed at the craniocervical junction. Serial follow-up MRI showed cyst enlargement with a fluid-fluid level. Four years later, the cyst reached a size of 15 mm and was surgically removed. The cyst contained cloudy fluid with a high protein concentration, without any bleeding or tissue fragments. Pathological examination confirmed the diagnosis of a neurenteric cyst. The patient recovered well, was discharged home, and has remained recurrence free for 2 years.

LESSONS

The growth dynamics of the relatively rapidly expanding neurenteric cyst at the craniocervical junction were monitored over time using MRI. This cyst exhibited the distinctive feature of a fluid-fluid level as it enlarged. Investigating the mechanisms underlying fluid-fluid level formation may offer novel insights into the pathogenesis of cyst enlargement.

https://thejns.org/doi/10.3171/CASE24180
Pituitary germinoma after resection of a mature third ventricular teratoma: illustrative case
Authors: Hallenberger Tim J , von Seth Emma , Roethlisberger Michel , Guzman Raphael , Soleman Jehuda
Published: July 2024

BACKGROUND

Metachronous intracranial germ cell tumors (iGCTs)—unrelated, histologically different iGCTs occurring at different time points—occurring within the same patient remain a rarity. Herein, the authors report such a case and discuss the literature and potential pathophysiological mechanisms leading to this phenomenon.

OBSERVATIONS

A 9-year-old boy presented with new-onset impaired balance, headaches, nausea, visual disturbances, and left facial paresis. Magnetic resonance imaging (MRI) scans revealed a suspected pineal region teratoma originating from the pineal gland with consecutive obstructive hydrocephalus. A mature teratoma was diagnosed and resected. Postoperative recovery was good, and the patient could return to his normal daily activities. However, a new, slowly progressive lesion in the sellar region with an enlarged infundibular stalk was detected on follow-up MRI 3.5 years after initial pineal region teratoma resection. Biopsy revealed a newly developed pure germinoma. The patient was treated with radiotherapy plus chemotherapy and remained relapse free at the last follow-up. Sixteen other cases have reported a surgically resected primary mature teratoma, wherein patients developed metachronous germinomas during follow-up. Different theories try to elaborate this phenomenon, yet none can completely account for it.

LESSONS

Although rare, metachronous iGCT is a phenomenon neurosurgeons should be aware of. In patients treated for iGCT, close long-term clinical, imaging, and laboratory follow-up is recommended.

https://thejns.org/doi/10.3171/CASE2443
KERJASAMA PERPUSTAKAAN UIN SUNAN GUNUNG DJATI BANDUNG DENGAN IAIN TERNATE MELALUI BENCHMARKING PERPUSTAKAAN
Authors: Zainal Abidin Asep , Saeful Rohman Asep
Published: July 2024

Library collaboration is one of the initiatives aimed at enhancing the quality of library services. One form of library collaboration is library benchmarking. Library benchmarking is the process of comparing libraries to identify best practices and procedures that can be implemented in one's own library. The purpose of this paper is to review the library collaboration between UIN Sunan Gunung Djati Bandung and IAIN Ternate through the benchmarking method, with a focus on the steps taken by the library management of UIN Sunan Gunung Djati Bandung as the entity under comparison. This research adopts a qualitative method, with data obtained through observation, interviews, and literature review. The research findings indicate that this collaboration has been ongoing for approximately two years, with various collaborative programs, including the development of a shared repository and the enhancement of human resources' competencies. Through benchmarking, this collaboration has aided both libraries, UIN Sunan Gunung Djati Bandung's library and IAIN Ternate's library, in improving their service quality and strengthening cross-library cooperation. It is hoped that the results of this research can offer valuable insights to other higher education institutions seeking to enhance their library services through collaboration and benchmarking approaches.
PENERAPAN MANAJEMEN PUSTAKALANA CHILDREN’S LIBRARY DALAM RANGKA MENINGKATKAN LAYANAN PERPUSTAKAAN
Authors: Afifah Azkia Rahmi , Khoerunnisa Lutfi , Setiawati Linda
Published: July 2024

This research is based on curiosity about how management functions are implemented at the Pustakalana Children's Library, including planning, organizing, actuating, and controlling functions. This research uses a descriptive qualitative approach. The informant in this research was a librarian at the Pustakalana Children's Library. The results will go through the data reduction, presentation, and conclusion drawing stages. The research results show that the management functions at the Pustakalana Children's Library are quite good. Because in the management of existing collections and how human resources are managed, efforts are made to run well.
PEMANFAATAN PENGETAHUAN TRADISIONAL SAAT PANDEMI COVID-19 DENGAN KEMAS ULANG INFORMASI
Authors: Fachmi Achmad
Published: July 2024

The COVID-19 pandemic has changed how people live and socialize, these things happen because people are asked to maintain their health and stay active at home and not leave the house if there is no urgent need. Society did this to prevent the high-speed and dangerous transmission of COVID-19. Therefore, people carry out daily activities from home, so the existence of social media is beneficial in meeting information needs. One is the need for information about traditional ingredients that can increase society immunity. At the time of the pandemic, news about traditional medicine sprang up, and it was a form of repackaging traditional knowledge about health. This study examines activities related to repackaging traditional knowledge information using social media during the COVID-19 pandemic to meet the socitety information needs regarding health information needs. This study aims to describe the role of social media in disseminating traditional knowledge and information repackaging as the preservation of traditional knowledge. The method used in this research is literature study, which is the writing, summarizing, synthesizing, and/or critiquing of the literature found as a result of a literature search. Qualitative descriptive analysis was used in this study's analysis process. The data obtained were then summarized and reviewed in depth so they could be described through text. The result is online media repackaging information so that information related to traditional knowledge can be easily accessed and accepted by the society. In addition, this pandemic creates momentum for information managers and institutions to be proactive in presenting the information needed by the society through digital media, one of which is social media. Because during the pandemic, people massively use social media to communicate and search for alternative information in treating and preventing COVID-19 with traditional medicines, information managers need to repackage information related to traditional knowledge to meet society needs.
DEVELOPMENT OF TEACHING MATERIALS BASED ON PROJECT BASED LEARNING FOR EDITING COURSE
Authors: Reni Oktaviani
Published: July 2024

The aim of this study was to provide project-based learning-based teaching materials for editing courses. This study makes use of the ADDIE paradigm for research and development. Writing learning outcomes, questionnaires, and observation were utilized to collect research data. Expert and peer assessments provided the data for the analysis. The findings demonstrated that successful learning outcomes were achieved by developing project-based learning-based teaching materials for fourth-year Indonesian Language and Literature Education Study Program students in the Editing course. This helps students revise their writing more effectively, which enhances their writing abilities. Thus, the research's implications concern students' comprehension of modifying and creating instructional materials in order to meet learning objectives. This tactic has a big impact on learning.
Differentiation of Juniperus deltoidеs R.P. Аdams in the Crimean-Caucasian Region According to the Variability of Microsatellite DNA Markers
Authors: Hantemirova E. V. , Radoukova Tz.
Published: July 2024

*e-mail: hantemirova@ipae.uran.ru
The structure of genetic variability of the prickly juniper Juniperus deltoides R.P. Adams (family Cupressaceae), an important component of Mediterranean arid and semi-arid ecosystems was studied. We used for the first time 5 nuclear microsatellite loci developed for another juniper species J. cedrus Webb Berthel. to genotype samples from 5 populations of J. deltoides located at the northeastern limit of the range in Eurasia (Western Crimea, Transcaucasia) and one Balkan population (Bulgaria). J. deltoides is characterized by an average level of genetic variability (He varies from 0.428 to 0.602) with the lowest values in the Crimean populations. Phylogenetic analyses revealed three genetic groups: Western Crimea, Transcaucasia (Krasnodar Territory) and Bulgarian population. Application of AMOVA to these groups showed statistically significant differentiation (9.9% of total variability, P 0.001). The first two groups correspond to the previously identified Asian group of J. deltoides, and the third group corresponds to the Balkan group. The differentiation of the Crimean populations from geographically close Caucasian populations is shown by us for the first time.
On the Disappearance of the Pleiotropic Effect of the N Gene of the Scale Cover in Carp (Сyprinus carpio L.)
Authors: Vinogradov E. V. , Karavaev V. V. , Balashov D. A. , Dement’ev V. N. , Simonov V. M. , Shart L. A. , Zhurenkova E. Yu.
Published: July 2024

Previously, numerous studies have shown a broad pleiotropic effect of the dominant allele of the scaly cover gene N. Carriers of this allele are inferior to recessive nn homozygotes in terms of growth rate and viability, and also differ in a number of physiological and meristic traits. In the present work, a case of the absence of pleiotropy was found: when scaleless females (ssNn) and males with scattered scale cover (ssnn) were crossed, naked and scattered offspring did not differ in growth rate, viability, and hematological parameters. The pleiotropic effect of the N gene was preserved only in terms of meristic characters. The absence of a negative effect of the N gene on productivity traits opens up the possibility of using naked carps in aquaculture.
Novel real-time PCR methods for bovine haplotypes HH3, HH6, HH7 diagnosis
Authors: Zubareva V. D. , Bytov M. V. , Zaitseva O. S. , Sokolova O. V.
Published: July 2024

Dairy cattle breeding is aimed at improving the productivity, mainly through the use of a limited number of breeding bulls. As a result, an increase in inbreeding is observed causing accumulation of heterozygotes-carriers of recessive lethal mutations. A rise in the number of carriers reduces the profitability of dairy farms, since the frequency of embryonic and post-embryonic mortality increases, and the fertility of cows decreases. This paper presents the results of the development of test systems for rapid and inexpensive diagnostics of genetically determined cattle diseases that are significant for animal husbandry, namely for Holstein haplotypes 3, 6 and 7. The diagnostic technology is real-time PCR using TaqMan probes. Carriers of the Holstein haplotype 3 were not found in any of the studied populations. The carrier frequencies for HH6 and HH7 were 0.95 and 1.92%, respectively. Carrier frequencies are consistent with the results of studies worldwide, however, it is worth noting that only few large-scale screening studies have been carried out, since causative loci have been mapped relatively recently.
Сравнительное исследование экологии питания Bothrocara brunneum и B. zestum (Zoarcidae) в глубоководных экосистемах северо-западной части Тихого океана
Authors: Напазаков В. В.
Published: July 2024

Приведены результаты анализа спектров питания и оценки трофических уровней и ниш двух видов слизеголовов – Bothrocara brunneum и B. zestum – из глубоководных районов Охотского моря и тихоокеанских вод Малой Курильской гряды. Оба вида питаются разнообразными бентосными и мезобентосными организмами, включая ракообразных, мезопелагических рыб, головоногих и двустворчатых моллюсков, полихет и иглокожих. Несмотря на вариабельность доминирующих компонентов пищи в разных регионах, ракообразные являются основной пищевой группой, и оба вида имеют сходные источники пищи и соответственно трофические ниши. Это подтверждено расчётом с помощью метода площадей стандартных эллипсов с учётом байесовской вероятности, который показал почти одинаковую ширину трофических ниш: 17.7 для B. zestum и 16.6 для B. brunneum. Фактические значения соотношения стабильных изотопов азота (δ15N) у компонентов пищи указывают на широкий диапазон трофических уровней изученных видов: от 2.08 до 4.36 у B. zestum и от 1.97 до 4.42 у B. brunneum, что свидетельствует об их пластичности в выборе кормовых объектов. Диапазоны значений соотношения стабильных изотопов углерода (δ13C) у пищевых компонентов, указывающие на базовые источники пищи, составили от –15.04 до –23.43‰ для B. zestum и от –15.07 до –23.43‰ для B. brunneum. В результате исследования получена новая информация о питании двух видов слизеголовов и определена их роль в трофической структуре экосистем исследованных районов.