bluuebunny/crossref_metadata_2025 huggingface dataset:
Nonmyeloablative bone marrow cells transplantation restores dystrophin synthesis in the muscles of MDX mice
Authors: Sokolova A. V , Timonina NA. A , Kravtsova V. V , Krivoi I. I , Skripkina N. S , Kaminskaia E. V , Mikhailov V. M
Published: April 2020

Duchenne muscular dystrophy is an X-linked recessive muscular dystrophy associated with a mutations in the dystrophin protein gene. The most common laboratory model of Duchenne muscular dystrophy is mdx mice. The striated muscle fibers of mdx mice are characterized by the absence of dystrophin, the presence of centrally located nuclei, and the high level of renewal of the striated muscle fibers. In addition, mdx mice show a morphological aberrations at neuromuscular junctions, expressed in the breakdown of large clusters of acetylcholine receptors in the form of branches into small clusters in the form of islets. One approach to treating muscular dystrophy in mdx mice may be the nonmyeloablative transplantation of wild-type bone marrow cells after X-ray irradiation of mdx mice at a dose of 3 Gy. The aim of this work is to evaluate the effect of nonmyeloabla-tive transplantation of wild-type bone marrow cells on dystrophin synthesis and the structure of neuromuscular junctions of mdx mice. Mdx mice were irradiated with X-rays at a dose of 3 Gy, after 24 hours was performed intravenous transplantation of bone marrow cells of C57BL/6 mice. The m. quariceps femoris and diaphragm were examined 2, 4, 6, 9, 12 months after transplantation. Muscle studies were performed using immunohisto-chemical methods of study (immunohistochemical staining with antibodies to dystrophin). The neuromuscular junctions were stained with tetramethylrodamine-a-bungarotoxin. After intravenous bone marrow cells transplantation, the part of dystrophin-positive muscle fibers in the muscle quadriceps femoris was shown to increase to a 27,6±6,7% 6 months after transplantation. After 12 months, the part of dystrophin-positive muscle fibers decreased to 5,1±1,1%. There was also an increase in the proportion of striated muscle fibers without centrally located nuclei and a decrease in the part of dead striated muscle fibers. Similar changes were found in the striated muscle fibers of the diaphragm of mdx mice. In addition, transplantation of bone marrow cells after irradiation at a dose of 3 Gy increases the part of neuromuscular junctions with normal structure. Thus, nonmy-eloablative transplantation of wild-type bone marrow cells can be considered as one way to treat monogenic disease of striated muscle fibers muscular dystrophy of mdx mice.
Cytotoxic and genotoxic effects of mitomycin C toward human endothelial cells
Authors: Sinitsky M. Y , Kutikhin A. G , Shishkova D. K , Asanov M. A , Ponasenko A. V
Published: April 2020

Mitomycin C is the most used for in vitro mutagenesis modeling alkylating agent belonging to the single-site mutagens. In the presented study, the in vitro cytotoxic and genotoxic effects of mitomycin C in endothelial cells of different arteries differ in the level of atherogenesis were studied. MTT colorimetric assay was used for assessment of cytotoxicity of different concentrations of mitomycin C, cytokinesis-block micronucleus assay - for estimating of genotoxic effects in human coronary and internal thoracic artery endothelial cells exposed to mutagen. After 6-h cultivation no decrease in the viability of cell cultures exposed to all studied concentrations of mitomycin C was observed; an increasing time of mutagenic load to 24 hours resulted in a significant (p
Pathomorphologic characteristics of venous vessels after the application of different methods of endovascular eliminating of venous reflux - experimental study
Authors: Abrosimova T. I , Kurmanskii A. V , Borisov A. A
Published: April 2020

Varicose veins have been the subject of a recent technologies of nontumescent treatment that outline the safety and effectiveness questions concerning proposed obliteration methods. The goal of this study is to analyze changes in the venous wall structure appearing as a result of using thermal tumescent and nonthermal nontumescent methods in compare. Methods: microscopic investigation of vein specimens of adult sheep (n=9) performed on 1, 7 and 100 day after procedure to determine the grade of damage and inflammation. Results: On the 1st and 7th days after the use of endovenous laser, endothelial destruction was 100%, with total depth damage of vein wall and total destruction of the elastic carcass, also traces of carbonization on the first and vaporization on the seventh day have been seen. In a result of the use of nonthermal method, there was a residual endothelium up to 30%; with the use of cyanoacrylate glue - up to 10%. In the long-term period of observation, glue masses undergo a sewage process and is preserved as separate lumps, there is an abundance of multicore macrophages with fragmented glue in the cytoplasm. Conclusion: the results allow us to consider nonthermal nontumescent methods as a possible alternative to thermal methods available in clinical practice.
ОЛИМПИАДА – РЕСУРС ПРОФЕССИОНАЛЬНОЙ ПОДГОТОВКИ ОБУЧАЮЩИХСЯ
Authors: Lebedeva Kseniya , Rybina Olesya
Published: April 2020

Рассматриваются вопросы организации профессиональной подготовки студентов педагогических направлений с точки зрения использования такого ресурса, как олимпиады. Авторы обращают внимание на существенные признаки предметных и методических олимпиад, выделяемые российскими и зарубежными исследователями. Среди них можно назвать комплексность, практикоориентированность, личную значимость для обучающегося. По результатам проведенного исследования (онлайн-опрос, анализ студенческих текстов) сделаны выводы о необходимости проведения олимпиад разного вида в процессе подготовки будущих педагогов.

The article considers the problem of professional training of students in pedagogical areas from the point of view of using such a resource as Olympiads. The authors pay attention to the essential features of the subject and methodological Olympiads identified by Russian and foreign researchers. Among them, the authors define such as complexity, practical orientation, and personal significance for the student. The complexity includes theoretical, practical, and methodological material in the Olympiad tasks. The practice orientation focuses on developing specific forms of interaction with students, lesson notes. The personal significance for students is development of educational independence. Based on the results of the conducted research (online survey, analysis of student texts), conclusions are made about the need to hold. Conclusions are drawn about efficiency of the different types of Olympiads in the process of training future teachers. The researchers think that participation of students in the Olympiad takes on a new meaning in their professional training, acting not only as a means of evaluating the acquired knowledge, skills, but also as a resource for developing their subject-methodical competencies and educational actions. The article is of interest to teachers of colleges and higher educational institutions and also students of pedagogical specialties.
МОДЕЛЬ УНИВЕРСИТЕТА 4.0
Authors: Fadeyev Aleksandr , Zmeyev Oleg , Gazizov Timur
Published: April 2020

В настоящее время в системе образования происходят значительные перемены. Если в дошкольном и общем образовании наконец-то сложился определенный порядок, то высшее образование меняется непрерывно. С одной стороны, происходит весьма болезненный переход на новые образовательные стандарты. В любом высшем учебном заведении сегодня можно слышать понятия «ФГОС третьего поколения», «ФГОС плюс», «ФГОС три плюс плюс», и эти слова часто произносятся с негативным оттенком: имеются сложности с самим процессом перехода, организация не успевает осмыслить и перейти на один стандарт, как на следующий год принимается новый. С другой стороны, происходят качественные изменения в организации образовательного процесса изнутри – наступает время трансформации университетов. Отчасти это происходит из-за влияния развития технологий, информатизации и запросов цифровой экономики. Предпринята попытка обобщить то, что сделано в области преобразования университетов, на основе анализа истории перехода от становления университета версии 1.0 до версии 4.0, или университета будущего, о которой активно говорится среди вузов программы 5-100. К модели университета 4.0 должны прийти в будущем все университеты мира. Данные результаты получены по итогам стратегической сессии по формированию Большего университета, проходившей в Томске со 2 по 6 декабря 2019 г.

Today, the educational system is undergoing significant changes. If a definite order finally takes place in preschool and general education, then higher education changes continuously. On the one hand, there is a very painful transition to new educational standards. In any higher education institution today you can hear the concepts of “third generation federal state education”, “federal state plus”, “federal state three plus plus” and these words are often pronounced with a negative connotation: there are difficulties with the transition process itself, the organization does not have time to comprehend and switch to one standard, and next year a new one is adopted. On the other hand, qualitative changes are taking place in the organization of the educational process from the inside – the time has come to transform universities. In part, this is due to the influence of technology development, informatization and the demands of the digital economy. In this paper, an attempt is made to summarize what has been done in the field of university transformation based on an analysis of the history of the transition from the formation of a higher educational university of the first version to version 4.0 or the university of the future, which is actively mentioned among universities of the 5-100 program, about the model that all universities of the world should come to in the future. These results were obtained as a result of a strategic session on the formation of the Greater University, held in Tomsk from December 2 to 6, 2019.
ИССЛЕДОВАНИЕ КИБЕРАДДИКЦИИ У ПОДРОСТКОВ С ПОМОЩЬЮ ОПРОСНЫХ ПСИХОДИАГНОСТИЧЕСКИХ МЕТОДОВ
Authors: Zakharova Tatyana , Sinogina Elena , Manina Anastasiya
Published: April 2020

Компьютерные информационные технологии в последние десятилетия активно внедряются в жизнь человека. В связи со стремительно развивающейся глобальной информатизацией и компьютеризацией общества, появилась необходимость диагностирования риска развития кибераддикции у подростков. Учеными и психологами разработано множество различных методик по выявлению кибераддикции. Дана общая характеристика часто применяемых в России опросных методов диагностики кибераддикции у детей и подростков, таких как шкала интернет-зависимости Чена (в адаптации К. А. Феклисова, В. Л. Малыгина); тест на интернет-зависимость В. А. Лоскутовой (Буровой); скрининговая диагностика компьютерной зависимости Л. Н. Юрьевой, Т. Ю. Больбот и т. д. Приводятся результаты исследования психоэмоциональных свойств личности подростков, предрасположенных к интернет-зависимости.

Computer information technologies in recent decades have been actively introduced into human life. In connection with the rapidly developing global informatization and computerization of society, a need has emerged for diagnosing the risk of developing cyber addiction in adolescents. Scientists and psychologists have developed many different techniques for identifying cyber addiction. This article presents a general description of the interrogation methods often used in Russia for diagnosing cyber addiction in children and adolescents, such as Chen’s Internet addiction scale (in adaptation by Feklisov K. A., Malygina V. L); test for Internet addiction by V. A. Loskutova (Burova); screening diagnostics of computer addiction by Yurieva L. N., Bolbot T. Yu., etc. The results of studies among students of the city of Tomsk with the aim of studying the psychoemotional personality traits of adolescents predisposed to Internet addiction are presented. The techniques presented in the article can be used by school psychologists and teachers to assess the attitude of adolescents to working at a computer or with gadgets, staying on the Internet, with the aim of developing preventive measures to prevent this type of dependence.
ГОТОВНОСТЬ К СЕМЕЙНОЙ ЖИЗНИ СТУДЕНТОВ, ОСТАВШИХСЯ БЕЗ ПОПЕЧЕНИЯ РОДИТЕЛЕЙ: ОПЫТ ЭМПИРИЧЕСКОГО ИССЛЕДОВАНИЯ
Authors: Fedosova Irina , Kibalnik Alena
Published: April 2020

Рассматривается социально-психологический феномен «готовность к семейной жизни». Подчеркивается ведущая роль семьи в подготовке юношей и девушек к будущей семейной жизни и формировании у них осознанного отношения к созданию собственной семьи. Особое внимание обращено на студентов, оставшихся без попечения родителей и получивших опыт воспитания в интернатных учреждениях. Акцентируется внимание на факторах, которые способствуют искаженному восприятию семьи, неправильному усвоению социальных ролей данной категорией обучающихся. Представлены эмпирические данные изучения сформированности социально-психологического феномена готовности к семейной жизни у студентов вуза, оставшихся без попечения родителей, по следующим критериям: когнитивный, ценностно-мотивационный, эмоциональный, операционально-деятельностный. На основе материалов диагностики утверждается необходимость формирования готовности к семейной жизни у данной категории обучающихся на основе специально разработанной программы, которая направлена на формирование ценности семьи; расширение знаний о семье, закономерностях ее развития, семейном этикете, психологии пола; пропаганду положительного опыта жизнедеятельности семьи и семейного воспитания; взаимодействие субъектов образовательного процесса по воспитанию семейных духовно-нравственных ценностей и ответственного родительства.

The article deals with the social and pedagogical phenomenon of preparedness to family life. The authors emphasize the leading role of family in preparing young people to the future family life and forming their responsible attitude to starting their own families. Special attention is paid to the group of students who were left without parental care and stayed at orphanages. The paper emphasizes the factors provoking distorted perception of family and incorrect understanding of social roles among this category of students. The authors present empirical data in studying preparedness to family life among university students left without parental care using the following criteria: cognitive criterion, value and motivational criterion, emotional criterion, and operational and activity criterion. Based on the diagnostics data, the authors affirm the necessity of forming preparedness to family life among this category of students on the basis of a specially developed program. The program aims at forming family values; expanding the knowledge about family, laws of its development, family etiquette, and gender psychology; promotion of successful experience of family life and education; interaction of education subjects in developing family and moral values and responsible attitude to being a parent.
ПОВЫШЕНИЕ КВАЛИФИКАЦИИ ПЕДАГОГИЧЕСКИХ РАБОТНИКОВ РОССИИ КАК СОВРЕМЕННОЕ ОБРАЗОВАНИЕ ВЗРОСЛЫХ
Authors: Ilakavichus Marina
Published: April 2020

Рассматривается проблема развития системы повышения квалификации педагогов России. Предлагается ее осмысление как части образования взрослых, составленного системной и внесистемной областями. Актуальным направлением развития образования взрослых предлагается формирование инфраструктуры и организация их координации. Это позволит полноценно реализовать принципы открытости и непрерывности, потенциал взаимодополнения формального и неформального видов образования. Неформальное образование рассматривается как ресурс общекультурного содержания образования взрослых, источник гуманизации, придающий ему мобильность, повышающий мотивацию обучающихся. На основе исследований запросов педагогов выделяется главный дефицит – неумение организовать взаимодействие с поколением Z. Он может быть восполнен в сообществах неформального образования при знакомстве с главными характеристиками социокультурной реальности – виртуализацией и воссозданием диалоговых площадок на общезначимые темы.

The problem of developing a system of advanced training for teachers in Russia is considered. As a conceptual basis of modernization, it is proposed to understand it as part of adult education, composed of systemic (implements formal education) and non-systemic (implements non-formal education) areas. An urgent direction in the development of adult education is the formation of the infrastructure of these areas, as well as the organization of their coordination. This will make it possible to fully realize the principles of openness and continuity, the potential for complementing formal and non-formal types of education. Non-formal education is considered as a resource for supplementing the deficit of the general cultural content of adult education, a source of humanization, which gives it mobility and increases the motivation of students. On the basis of the research of the requests of pedagogical workers of Russia, the deficits of professional competencies recognized by them, the main deficit is identified – inability to organize interaction with generation Z, ignorance of the specifics of the modern sociocultural situation. It can be replenished in non-formal education communities when becoming acquainted with the main characteristics of sociocultural reality – virtualization and the recreation of dialogue platforms on topics of general interest.
ЯЗЫК ДИРИЖЕРСКОГО ЖЕСТА В КОНТЕКСТЕ ПЕДАГОГИЧЕСКОЙ ПРАКСЕОЛОГИИ
Authors: Tsarev Vjacheslav
Published: April 2020

В статье автор с использованием принципов системного анализа рассматривает некоторые особенности достаточно молодого искусства – дирижёрского – в динамике его генезиса и развития, обусловленного поступательной эволюцией музыкального искусства в целом. С позиций педагогической праксеологии на конкретных примерах выдающихся исполнителей (Арнольда Каца, Евгения Мравинского, Герберта фон Караяна, Александра Свешникова и др.) описаны профессиональные и личностные качества, которыми должен обладать дирижёр оркестра или хора (особенно начинающий дирижёр), показаны особенности творческого взаимодействия руководителя коллектива и исполнителей. Характеризуя дирижирование как объект визуального восприятия, автор выделяет ведущую роль Ильи Александровича Мусина в становлении техники дирижёрского искусства в России, обозначении главенствующей роли жестов «триады» – «внимание», «дыхание», или «ауфтакт», и «атака звука». При этом, определяя истинную природу искусства дирижирования, автор статьи отмечает единство двух основных составляющих: технической стороны и выразительной. Подчёркивая первичность постановки, технической оснащённости мануального аппарата, автор актуализирует значимость художественного прочтения дирижёрского жеста, предполагающего эмоциональное выражение замысла, краски, души композитора.

In the article, from the standpoint of system analysis the author considers some features of a fairly young conductor art in the dynamics of its genesis and development, due to the progressive evolution of musical art in general. From the standpoint of pedagogical praxeology, specific examples of outstanding performers (Arnold Katz, Evgeny Mravinsky, Herbert Von Karayan, Alexander Sveshnikov, and others) describe the professional and personal qualities that an orchestra conductor or choir should possess (especially a novice conductor), and features of the creative interaction of the leader collective and performers. Describing conduction as an object of visual perception, the author identifies the leading role of Ilya Aleksandrovich Musin in the formation of the technique of conducting art in Russia, designating the gestures of “triad” – “attention”, “breath” or “auftakt” and “attack of sound”. At the same time, determining the true nature of the art of conducting, the unity of the two main components is noted – the technical side and the expressive one. Emphasizing the primacy of the production, the technical equipment of the manual apparatus, the author updates the significance of the artistic interpretation of the conductor’s gesture, which presupposes the emotional expression of the intention, color, soul of the composer.
Examining Succession and Replacement Planning in Work organizations
Authors: Gabriel Peace Ifidon , Biriowu Chris Samuel , Dagogo Eli Legg-Jack
Published: April 2020

Succession planning and replacement planning are both strategies that are incredibly important to the lifeline of any organization. Succession planning is a deliberate and systematic effort by an organization to ensure leadership continuity in key positions, retain and develop intellectual and knowledge capital for the future, and encourage individual advancement. Replacement planning is the process of identifying short-term and long-term emergency backups to ﬁll critical positions or to take the place of critical people. This paper examines the role of succession and replacement planning in improving organizational performance. It established the importance; types; features and objectives of succession planning in the workplace. The paper juxtaposed replacement and succession planning in the workplace, established the development plan of replacement planning and examines how succession and replacement planning helps to improve on the performance of the organization. The paper identified that succession planning and replacement planning are two different strategies; succession planning is oriented around developing people through training, mentoring, coaching, while replacement planning is focused on meeting the demands of emergencies in the organization. The paper further identified that from the perspective of the workplace succession planning helps the organization to access the risk in key position, minimizes risk through appropriate compensation, recognition and management, and assuring the readiness of successors by identifying and training high potential employees. Replacement planning assumes a stable and unchanging organizational structure, which encourages silo-d thinking about talent since in most cases; replacements come from a specific specialty area. The paper concludes that these strategies are incredibly important to the lifeline of any organization as they both assists to improve organizational performance. The paper recommends that Organizations should make use of replacement planning and succession planning; together they can mitigate the risks of any organization going out of business.
Comparative Analysis of Emitted Magnetic Fields from Liquid Crystal Display (LCD) and Light Emitting Diode (LED) System
Authors: Bakare Bodunrin Isa , Taol Victor T. , Orike Sunny
Published: April 2020

This paper present the Comparative analysis of emitted magnetic fields from Liquid Crystal Display(LCD) and that of Light Emitting Diode (LED) system. A total of eighteen Liquid Crystal Display and Light Emitting Diode  Monitors from different manufacturers were used. The magnetic field was measured using a trifield guass meter. The trifield guass meter was placed perpendicularly to the monitors at 5cm steps from the monitor up to 70cm and the magnetic field from each monitor was recorded in milligauss. The result showed that the magnetic field of the liquid crystal display monitors is almost 2 times greater than that of the light-emitting diode monitors. The obtained results were compared with international occupational and general public recommended exposure limit and The result was found to be below the permissible dose limit according to the IEEE( Institute of Electrical and Electronics Engineering) standard. Although there is minimal evidence of the health risk associated with the use of Visual Display Units (VDUs) and it is inconclusive.”
A Model Approach to Analytically Identify Stuck Pipe and Its Mechanism in Wellbore
Authors: Oriji Boniface A. , Aire Iribhogbe Silas
Published: April 2020

Stuck pipe incidents translate to non-productive time. There is a need to mitigate stuck pipe incidents which can be achieved by conforming to recommended practices. Also, quick diagnosis is necessary in order to free a stuck pipe. Trial-and-error method can further complicate the situation. This work aims at diagnosing stuck pipe mechanisms and recommend practices to free a stuck pipe. spANALYZE also estimates the axial force and torque needed to free a stuck pipe caused by differential sticking. spANALYZE is a thick desktop client application developed in C# using the Microsoft Visual Studio 2019 development environment. It is an object-oriented .NET application that utilizes the Windows Presentation Foundation (WPF) architecture for its user interface. Each of the analyzers within spANALYZE were implemented generically as a list of nodes, representing the concept of a flow chart. New analyzers can easily be added simply by programmatically defining each node in the flow chart. Each node has a node identifier, a node type, node text, and the node identifiers of each answer – yes, no and restricted. spANALYZE presents the following benefits: quick and early detection of stuck pipe mechanisms, propose recommended action steps to free pipe, calculate stuck pipe depth, compute the torque and axial force needed to free a stuck string.
Influence of Performance Appraisal on Performance of Civil Servants in Kenya
Authors: Elhadi Yahya Idriss
Published: April 2020

This article is part of a doctoral project entitled “Results-Based Management and Performance of Civil Servants in Kenya”. The purpose of the article is to determine the influence of performance appraisal on performance of civil servants. During the last three decades performance appraisal has become a popular instrument in public sector reform agenda under the New Public Management which is results-driven. Its application has since become an important human resource management practice in the public sector performance management systems. The underlying aim is to foster organizational and individual efficiency and effectiveness in the public sector. Applying both descriptive survey and case study designs with a mixed research strategy, the study found that performance appraisal has a significant positive influence on performance of civil servants in Kenya. This means that, when performance appraisal process is effective, civil servants learn about themselves; gaining sense of personal worth, become more knowledgeable about their tasks, and more imperatively they learn about what are mostly valued by the employer. The study recommends for pragmatic use of performance appraisal since has significantly and positively influenced the performance of civil servants in Kenya.
The Seven-Dimensional Spacetime in the Planck Vacuum Theory and the Structure of the Electron and Proton Cores
Authors: Daywitt William C.
Published: April 2020

The electron and proton cores in the Planck vacuum (PV) theory are reccognizable elementary particles that obey the manisestly covariant Dirac equation and that are coupled to the PV state. (This statement and similar statements to follow also apply to the electron-core and the proton-core antiparticles.) This paper derives the corresponding 2x1 spinor-wavefunction equations for these cores, leading to a 7-dimensional spacetime that consists of two 4-dimensional spacetimes, the result of a bifurcated vacuum state. Both the electron and proton cores contain structure, where the electron core structure is orders of magnitude smaller than the proton-core structure.  The core structure is easily reccognized in the calculations, as is particle-antiparticle annihilation. The difference between the electron and proton cores and their electron and proton particles is that the latter contain radiative corrections.
PRIMENA BIM-A U UPRAVLJANJU PROJEKTIMA
Authors: Jovanov Aleksandra
Published: April 2020

BIM (eng. Building Information Modeling) je izgradnja digitalnog integrisanog modela (informacija) postojeće ili buduće izgrađene okoline.
FUNKCIONALNE KARAKTERISTIKE DISTRIBUTIVNIH CENTARA U DISTRIBUTIVNIM STRATEGIJAMA
Authors: Nović Nebojša
Published: April 2020

U ovom radu izučavaju se osnovne komponente, pokazatelji i iskustva u realizaciji distribucije proizvoda sa ciljem njihove sistematizacije. Data su najpre uvodna razmatranja vezana za logistiku, distribuciju i značaj ovih funkcija za poslovanje kompanija. Opisane su različite strukture distributivnih kanala. Objašnjen je koncept logističkih centara, i u okviru njega distributivnih centara, kao jedan od načina za racionalizaciju i unapređenje distributivnih procesa. Praktični značaj distributivnih strategija je prikazan kroz poređenje poslovnih modela dva giganta modne industrije: kompanije Zare i H&M. Elementi za poređenje ovih kompanija su: vrsta lanca snabdevanja; zavisnost od IT sistema; proces dizajniranja; strategija proizvodnje; strategija distribucije; strategija maloprodaje; način segmentacije tržišta; politika promocije i orijentacija na društvenu odgovornost. Na osnovu iznetog u završnom delu izneti su zaključci.
REVITALIZACIJA NAPUŠTENE FABRIKE RIBE „RIBOCENTAR“ U APATINU
Authors: Gnjidić Tijana
Published: April 2020

Tema ovog rada jeste revitalizacija objekta napuštene fabrike ribe „Ribocentar“.
PROJEKAT TURISTIČKO-STAMBENOG KOMPLEKSA NA TREBEVIĆU
Authors: Rakić Aleksandra
Published: April 2020

Projekat turističko-stambenog kom­pleksa na Trebeviću obuhvata različite aspekte projekto­vanja nastalih iz potreba okoline u konkretnom fizičkom i socijalnom kontekstu. Bavi se formiranjem urbanističke cjeline na planinskom području, ispitivanjem funkcija i njihovih odnosa, kao i relacijom između prirode i samih objekata. Programska kompleksnost je uslovljena sav­remenim parametrima u arhitekturi. Sprovedeno je pet studija slučaja u kojima se ispitivao odnos ovih para­metara i kao rezultat, stvoreni su segmenti koncepta za projekat.
REŠENJE ENTERIJERA MULTIFUNKCIONALNOG PROSTORA U OBJEKTU NEKADAŠNJE HLADNJAČE „CENTROSLAVIJA“
Authors: Petrović Jelena
Published: April 2020

Rad se bavi revitalizacijom i rešenjem enterijera postojećeg objekta, hladnjače „Centroslavija“ u Novom Sadu. Projekat revitalizacije bazira se na istraživanju istorijskih, socijlanih i kulturnih tema, kao i studijama slučaja. Na osnovu sprovedenih istraživanja rad se dalje bazira na valorizaciji današnjeg stanja ob­jekta, a kao jedna od glavnih tema rešavanja problema biće revitalizacija objekta, odnosno promejna njegove namjene u multifunkcionalni poslovni prostor kao i reše­nje enterijera. Uzimajući u obzir kontekst, novi program i potrebe korisnika dobijeno je rešenje koje čini jednu cje­linu koja objedinjuje funkcionalne procese i programske cjeline koje ovakav objekat mora da sadrži.
UMETNIČKA GALERIJA SA URBANISTIČKIM REŠENJEM OBALE LIMA U PRIBOJU
Authors: Gogalić Inda
Published: April 2020

Tema ovog rada jeste uređenje šetališne staze na obali reke Lim, kao i koncipiranje objekta umetničke galerije koja je smeštena u njenom produžetku. Cilj projekta jeste uvođenje pejzaža iz okruženja u arhitektonski objekat i integracija slobodnog vremena sa vremenom posvećenom obrazovanju iz oblasti kulture.
AMBASADA ČEŠKE REPUBLIKE U ETIOPIJI
Authors: Blagojević Nikolina
Published: April 2020

Rad se bavi proučavanjem lokacije i terena u Etiopiji gdje je potrebno da se isprojektuje bezbjednosni objekat Češke ambasade uz prateće objekte stanovanja i poslovanja. Potrebno je da projekat posjeduje urbanističko i arhitektonsko rješenje.
SISTEM ZA AUTOMATIZACIJU ORGANIZACIJE PLANINARSKIH AKTIVNOSTI RAZVIJEN U .NET TEHNOLOGIJI
Authors: Jovanović Stana
Published: April 2020

U okviru ovog rada realizovan je razvoj veb i desktop aplikacija kojima se omogućava poboljšan i brz proces poslovanja kompanije koja se bavi organizacijom putovanja za ljubitelje prirode. Predstavljen je način implementacije dve aplikacije, jedna je kreirana u veb tehnologiji ASP.NET MVC i druga u WPF tehnologiji, koje predstavljaju sastavni deo Microsoft-ovog .NET okruženja.
Practical implementation of the methods to assess the effectiveness of the insurance company's internal control system
Authors: Turgaeva A.A.
Published: April 2020

Subject. This article deals with the issues of building an internal control and audit system of insurance companies and improving its efficiency.
Objectives. The article aims to assess the effectiveness of the internal control system of the insurance company on the basis of the original quantitative and qualitative indicators presented in previous articles.
Methods. For the study, I used statistical inquiry and data handling procedures, mathematical techniques, grouping, and expert assessment methods.
Results. The article presents a calculated integrated index of the internal control system effectiveness of the insurance company. It assesses the organization of the internal control system through testing.
Conclusions. By assessing the internal control system of the insurance company using quantitative and qualitative indices, it is possible to identify the level of effectiveness of the internal control system and the system's weaknesses. Employee surveys can improve the level of internal control by exposing the auditors' substandard work.
Innovative development of the region during the modernization phase
Authors: Balakina G.F.
Published: April 2020

Subject. This article deals with the current trends in regional innovation processes that are taking place in Russia.
Objectives. The article aims to justify and systematize trends in the innovation sector of the region, determine their dependence on the rate of economic growth and development of the country's technological complex.
Methods. For the study, I used the methods of systems, economic, and statistical analyses, SWOT analysis, classification, comparison, and expert assessment. Statistics and analytical data for the Russian Federation and the Tyva Republic are the basis for analysis.
Results. The article highlights the main trends in the innovation-driven development of the regions of Russia, elements of the innovation infrastructure, and the regional innovation system framework. It identifies the obstacles to the transition to the knowledge economy, considering the Tyva Republic as a case study.
Conclusions. The Tyva Republic has every opportunity to intensify innovation processes. On the basis of attracting investments, the Republic has begun forming local competitive innovation clusters. It is advisable to create a regional infrastructure to promote innovation and a system of stimulation and selection of innovative initiatives of the population.
Financial literacy of the population of the Tyva Republic
Authors: Soyan Sh.Ch. , Sevek V.K. , Taibyl R.S.
Published: April 2020

Subject. This article deals with the issues of determining the level of financial literacy of the population of the Tyva Republic.
Objectives. The article aims to analyze the level of financial literacy of the population of the Tyva Republic and identify factors that cause the financial illiteracy rates.
Methods. For the study, we used a questionnaire method within a sociological survey.
Results. The article presents results of the sociological survey of respondents and highlights the main reasons for the financial illiteracy of the majority of the population of the Tyva Republic.
Conclusions. The results obtained can be taken into account when developing the area's socio-economic development programmes improving the quality of life of the population.
Providing additional education services for children: Challenges and solutions
Authors: Brodovskaya Yu.I. , Smirnova T.A.
Published: April 2020

Subject. This article considers the issues of provision of supplementary education services for children and methodological tools for the formation of educational environment.
Objectives. The article aims to assess the level of development of the system of supplementary education of children in Krasnoyarsk and offer a methodological approach to improving the management decision-making procedure in the formation of a portfolio of supplementary education services at the municipal level.
Methods. For the study, we used the methods of theoretical, empirical, and logistic analyses, and sociological studies.
Results. The article offers concrete solutions to the lack of a methodological approach to providing supplementary education services, considering one of the micro-districts of Krasnoyarsk as a case in point. It also offers tools that can be used by public authorities to organize educational space at the municipal level.
Conclusions. A unified methodological approach should be used to provide a system of supplementary education, taking into account financial means, as well as differentiation in the distribution of educational facilities throughout the area. The relevance of the set of supplementary education services and consumer preferences should be taken into account, as well.
An analysis of the investment attractiveness of the Chelyabinsk Oblast using the eigenstate method
Authors: Bunova E.V. , Buslaeva O.S. , Serova V.S.
Published: April 2020

Subject. This article deals with the issues related to the socio-economic development of Russia's regions.
Objectives. The article aims to develop a methodology for analyzing indicators that characterize the investment force of attraction of the region.
Methods. For the study, we used an integrated economic and mathematical technique based on an analysis of the region's indicator proper states.
Results. The article proposes a methodology for analyzing the impact of socio-economic and environmental indicators of the region on its investment attractiveness. It demonstrates the use of this methodology through the analysis of the investment attractiveness of the Chelyabinsk Oblast by building an optimal model of socio-economic development and environmental safety using the proper state method.
Conclusions. The proposed methodology can be used for any region of Russia when determining the region's economic growth path and increasing its environmental responsibility.
Systematization of the smart city civil engineering infrastructure
Authors: Popov E.V. , Semyachkov K.A. , Zhunusova K.V.
Published: April 2020

Subject. This article explores the basic elements of the engineering infrastructure of smart cities. Objectives. The article aims to systematize theoretical descriptions of the engineering infrastructure of a smart city. Methods. For the study, we used a logical analysis and systematization. Results. The article highlights the main areas of infrastructure development of smart cities. Conclusions. Improving process management mechanisms, optimizing urban infrastructure, increasing the use of digital technologies, and developing socio-economic innovation improve the quality of the urban environment in a digitalized environment. And improving the efficiency of urban planning and security, studying its properties and characteristics, and forming an effective urban information system lead to its functional transformations.
Language Policy of Ukraine: Major Results
Authors: Markova E. A.
Published: April 2020

In its almost three decades history, Ukrainian language policy has gone through several stages of its development. Formed before the collapse of theUSSR, the Ukrainian elite actively used the issue of the language to achieve its political goals. Even at the turn of the 80-90s of the last century, the issue on the status of the Russian language was in the focus of the political struggle. Relying on the party and bureaucratic apparatus support, the nationalistically-spirited elite ofUkrainebegan to use the language issue for winning over the population of the southeastern regions. At that time, it was of great importance, since before the collapse of theUSSR, the Ukrainian elite was interested in preventing the growth of protest sentiment within the country. In subsequent years, the issue of the Russian language status has repeatedly become the subject of intense political battles and speculation as well. The Party of Regions, the Communist Party exploited the theme of “protecting” the Russian language to consolidate their electorate before the parliamentary and presidential elections. Concurrently, the Western Ukrainian elites defended a different position, proposing to expand the scope of the Ukrainian language while at the same time confine the Russian language.

Despite the turmoil between the Western Ukrainian and Eastern Ukrainian elites, especially during the pre-election periods,Ukrainegradually “drifted” towards restricting the use of the Russian language and expanding Ukrainian in education and culture.

The situation in the linguistic sphere inUkrainechanged dramatically after 2014, when representatives of nationalist forces came to power. It became a policy to revise the legislation governing on the use of languages of national minorities, to which the Russian language began to fall into. As a result, the possibilities for using the Russian language were confined, while enhancing the role of the Ukrainian language. This situation has already aggravated the relations betweenUkraineand neighboring countries, in which they negatively evaluatedUkraine’s policy in the language sphere. In addition, limited scope for the Russian language has ratcheted up tension within the country, provoking new inter-regional contradictions.
A saúde na escola como meio de prevenção da gravidez na adolescência: uma breve análise
Authors: Ramos Lázaro Saluci , Silva Joelma Abreu , Soares Tiago Ferreira , Carvalho Josemar Soares , Fontão Simone Sedano , Mota Marcela da Cruz , Dos Santos Leonardo , Duarte Leandro Riso , Da Silva Vânia dos Santos , De Oliveira Micheli Rodrigues
Published: April 2020

Objetivo: O objetivo da presente pesquisa é apontar as políticas públicas que podem ser adotadas pela saúde pública em consonância com o ambiente escolar, para solucionar o grave problema social que se tornou a gravidez na adolescência. Revisão Bibliográfica: O constante aumento de casos de gravidez na adolescência trouxe consigo um problema ainda maior, as ineficazes maneiras de tratar do problema social. Quando o assunto chega ao ambiente escolar ele pode ser castrado pelo conservadorismo social ou mal dirigido por falta de profissionais com experiência na área. Um projeto ligado a formação continuada para professores e especializações específicas para profissionais da saúde é a nova aposta para ampliar a margem de capacitação e tornar o ambiente escolar um ponto de referência no combate a gravidez precoce. Considerações finais: Como se trata de um problema recorrente, as famílias estão cada vez mais disponíveis a colaborar, todavia, alcançar lares bloqueados pelo conservadorismo que é consequência da desigualdade social, se tornou um entrave.
Uso de geotecnologias aplicadas em serviços de saúde: revisão Integrativa
Authors: Lima Kezia Porto , Neves Dirceu Cavalcante , Santos Natália Moreira , Rocha Sarah Laís , Valente Aline Santana Oliveira , Souza Monica Cristina De
Published: April 2020

Objetivo: Analisar o volume e características das produções científicas sobre uso de geotecnologias aplicadas em serviços de saúde. Métodos: Trata-se de uma revisão integrativa da literatura das bases de dados: Literatura Latino-Americano e do Caribe em Ciências da Saúde (LICAS), Scientific Electronic Library Online (SciELO) e Literature Analysis and Retrieval System Online (MEDLINE), com a utilização do programa Excel®, para criação de uma planilha com informações das publicações selecionadas para compor o estudo. Resultados: Identificou-se 20 artigos que respondiam aos nossos objetivos, destes apenas 30% eram nacionais e 70% internacionais. O ano de maior publicação foi 2014 (30%) e os enfermeiros e médicos realizaram 70% dos estudos. A revisão demonstrou que 60% das publicações foram de periódicos internacionais, sendo o Brasil e os E.U.A (30%) responsáveis individualmente por 30% das publicações. A metodologia mais frequente foi pesquisa exploratória do tipo pesquisa bibliográfica (25%); todas as publicações foram publicadas em periódicos diferentes. Conclusão: Foi constatado através desse estudo uma carência de produções carência de produções científicas sobre a temática em território nacional no campo da saúde. Tais tecnologias são ferramentas de excelência, evidenciando sua importância na promoção de melhores condições no campo da saúde, como: utilização consciente dos recursos, melhor acessibilidade dos usuários e redução de custos. Espera-se dos profissionais da saúde maior realização de estudos sobre a temática, bem como, desperte interesse para a construção de geotecnologias.
The potentialities of corpus-based techniques for analyzing literature
Authors: Hussein Khalid Shakir
Published: April 2020

This paper presents an attempt to explore the analytical potential of five corpus-based techniques: concordances, frequency lists, keyword lists, collocate lists, and dispersion plots. The basic question addressed is related to the contribution that these techniques make to gain more objective and insightful knowledge of the way literary meanings are encoded and of the way the literary language is organized. Three sizable English novels (Joyc's Ulysses, Woolf's The Waves, and Faulkner's As I Lay Dying) are laid to corpus linguistic analysis. It is only by virtue of corpus-based techniques that huge amounts of literary data are analyzable. Otherwise, the data will keep on to be not more than several lines of poetry or short excerpts of narrative. The corpus-based techniques presented throughout this paper contribute more or less to a sort of rigorous interpretation of literary texts far from the intuitive approaches usually utilized in traditional stylistics.
Optimized Synthesis of 7-Aza-Indazoles by Diels–Alder Cascade and Associated Process Safety
Authors: Brach Nicolas , Le Fouler Vincent , Bizet Vincent , Lanz Marian , Hoehn Pascale , Gallou Fabrice , Bailly Corinne , Parmentier Michael , Blanchard Nicolas
Published: April 2020

Although pyrimidines are not among the most reac-tive partners in intramolecular inverse-electron de-mand [4πs+2πs] reactions with alkynes, they could be activated under mild and practical conditions, leading to fused nitrogen-containing heterocycles. We report an optimized synthesis of a 5-iodo-7-aza-indazole by a one-pot Diels–Alder cascade that starts from a pyrimidine substituted in the 2-position by an (alkynyl)hydrazone. The safety of the process was carefully studied by DSC studies. Eventually, a selection of cross-coupling reactions of 17 was studied and allowed the introduction of carbon- and nitrogen-based nucleophiles at the C5-position in good to excellent yields.
DNA Nucleobase Under Ionizing Radiation: Unexpected Proton Transfer by Thymine Cation in Water Nanodroplets
Authors: Semmeq Abderrhamane , Badawi Michael , Hasnaoui Abdellatif , Ouaskit Said , Monari Antonio
Published: April 2020

The effects of ionizing radiation on DNA constituents is a widely studied fundamental process using experimental and computational techniques. In particular radiation effects on nucleobases are usually tackled by mass spectrometry in which the nucleobase is embedded in a water nanodroplet. Here we present a multiscale theoretical study revealing the effects and the dynamics of water droplets towards neutral and ionized thymine. In particular, by using both hybrid quantum mechanics/ molecular mechanics and fully ab initio molecular dynamics we reveal an unexpected proton transfer from thymine cation to a nearby water molecule. This leads to the formation of a neutral radical thymine and a Zundel structure, while the hydrated proton localizes at the interface between the deprotonated thymine and the water droplet. This observation opens entirely novel perspective concerning the reactivity and further fragmentation of ionized nucleobases.