bluuebunny/crossref_metadata_2025 huggingface dataset:
Shape and topological derivatives as Hadamard semidifferentials
Authors: Delfour Michel C.
Published: January 2025

The object of this paper is to further investigate the notion of shape and topological derivatives in the light of the general notion of Hadamard semidifferential for a function defined on a subset of a topological vector space.

The use of semitrajectories and the characterization of the adjacent tangent cone provide simple tools for defining Hadamard semi-differentials and differentials without a priori introduction of geometric structures such as, for instance, a differential manifold. Such a simple notion retains all the operations of the classical differential calculus, including the chain rule, for a large class of nondifferentiable functions, in particular, the norms and the convex functions. It also provides a direct access to functions defined on a lousy set or a manifold with boundary.

This direct approach is first illustrated in the context of the classical matrix subgroups of the general linear group GL(n) of invertible n×n matrices, which are the prototypes of Lie groups. For the shape derivative we have groups of diffeomorphisms of the Euclidean space ℝ
n
with the composition operation, and the adjacent tangent cone is a linear space; for the topological derivative we have the group of characteristic functions with the symmetric difference operation and the adjacent tangent cone is only a cone at some points.
Analysis and application of a lower envelope method for sharp-interface multiphase problems
Authors: Laurain Antoine
Published: January 2025

We introduce and analyze a lower envelope method (LEM) for the tracking of motion of interfaces in multiphase problems. The main idea of the method is to define the phases as the regions where the lower envelope of a set of functions coincides with exactly one of the functions. We show that a variety of complex lower-dimensional interfaces naturally appear in the process. The evolution of phases is then achieved by solving a set of transport equations. In the first part of the paper, we show several theoretical properties, give conditions to obtain a well-posed behaviour, and show that the level set method is a particular case of the LEM. In the second part, we propose a LEM-based numerical algorithm for multiphase shape optimization problems. We apply this algorithm to an inverse conductivity problem with three phases and present several numerical results.
Sufficient approximate optimality condition for the inverse one-phase Stefan problem
Authors: Lipnicka Marta , Lipnicki Artur , Nowakowski Andrzej
Published: January 2025

We investigate the identification problem for the one-phase Stefan problem. As the inverse Stefan problem is not well posed, an optimal control problem is considered instead. In the paper we develop a dual dynamic programming approach to derive sufficient approximate optimality conditions for that optimal control problem. As a next step we formulate and prove a verification theorem for approximate solution. The verification Theorem 4.1 is the basis for the development of a numerical algorithm. Having the verification theorem we do not need the convergence of our algorithm.
El Trabajo Decente en las Regiones de México
Authors: Puebla-Gutierrez Marta Argentina , Bracamontes-Nevárez Joaquín , Camberos-Castro Mario
Published: January 2025

Objetivo: analizar el trabajo decente en México y las regiones que lo configuran. Metodología: mediante la técnica de componentes principales se ha calculado un Índice de Empleo Decente (IED) con datos de la Encuesta Nacional de Ocupación y Empleo del INEGI (2022). Resultados: Las regiones Norte y Centro con un índice de empleo decente Muy Alto y Alto respectivamente, reflejan la mejor situación del empleo decente en el país; mientras que, la región Centro-Norte clasifica en el estrato Medio, igual que el país. Para la región Sur se obtuvo un índice de empleo decente Muy Bajo, lo que muestra la peor situación en el impulso y difusión del trabajo decente en México. Limitaciones: el Índice de Empleo Decente que se presenta fue calculado solo para el país, las regiones y estados, pero no a escala sectorial. Conclusiones: son trece los estados en situación crítica por tener un IED que les clasifica en el estrato Bajo y Muy bajo, en la región Centro-Norte: Nayarit, San Luis Potosí, Sinaloa, Michoacán y Zacatecas, en la Región Centro: Guanajuato, Hidalgo y Puebla; mientras que, en la región Sur: Chiapas, Guerrero, Oaxaca, Tabasco y Veracruz. Por lo tanto, es esencial dirigir esfuerzos al impulso y difusión del trabajo decente en estas trece entidades.
ANALISIS TIMBULAN DAN KOMPOSISI SERTA NILAI EKONOMIS LIMBAH PADAT RUMAH SAKIT UNIVERSITAS UDAYANA
Authors: Cahyaning Putri Galuh , Herry Purnama I Gede
Published: January 2025

ABSTRAK
Rumah sakit merupakan sektor penghasil sampah yang cukup banyak setiap harinya dan terkadang bersifat toksik, terutama pada sampah padat baik itu sampah medis maupun non medis. Total jumlah Rumah Sakit di Indonesia mencapai 2.601, termasuk di antaranya Rumah Sakit Umum dan Rumah Sakit Khusus. Jumlah ini mengalami peningkatan dari tahun sebelumnya. Seiring dengan peningkatan jumlah rumah sakit di Indonesia setiap tahunnya, maka jumlah produksi limbah, baik dalam bentuk padat maupun cair, juga akan meningkat secara signifikan. Penelitia ini bertujuan untuk mengetahui timbulan, komposisi dan potensi nilai ekonomi dari limbah padat di rumah sakit. Jenis penelitian ini adalah cross sectional dengan pendekatan deskriptif kuantitatif. Populasi dan sampel penelitian yang digunakan adalah limbah padat Rumah sakit Universitas Udayana. Hasil penelitian menunjukan timbulan dan komposisi sampah rumah sakit dipengaruhi dengan aktivitas dan kunjungan di rumah sakit, sedangkan potensi ekonomi memberikan dampak yang baik bagi lingkungan serta keuntungan bagi rumah sakit.
Kata kunci: Pengelolaan limbah, timbulan sampah, komposisi sampah, nilai ekonomis sampah
 
ABSTRACT
Hospitals are a sector that produces quite a lot of waste every day and is sometimes toxic, especially solid waste, both medical and non-medical waste. The total number of hospitals in Indonesia has reached 2,601, including general hospitals and special hospitals. This number has increased from the previous year. Along with the increase in the number of hospitals in Indonesia each year, the amount of waste production, both in solid and liquid form, will also increase significantly. This study aims to determine the generation, composition and potential economic value of solid waste in hospitals. This type of research is cross sectional with a quantitative descriptive approach. The population and research sample used were solid waste from Udayana University Hospital. The results show that the generation and composition of hospital waste is influenced by activities and visits to the hospital, while the economic potential has a good impact on the environment and benefits for the hospital.
Keywords: Waste management, waste generation, waste composition, waste economic value
GAMBARAN PERSEPSI PENGGUNA FITUR RESERVASI RAWAT JALAN PADA APLIKASI SIPRAJA RUMAH SAKIT BHAYANGKARA DENPASAR
Authors: Risma Adhi Pramita Dewa Ayu , Putu Januraga Pande
Published: January 2025

ABSTRAK
Permintaan pelayanan rawat jalan semakin meningkat. RS Bhayangkara Denpasar telah menerapkan sistem pendaftaran daring dengan adanya fitur reservasi rawat jalan pada aplikasi SIPRAJA sebagai salah satu upaya meningkatkan pelayanan. Namun masih dijumpai antrian panjang di loket pendaftaran. Salah satu metode untuk melihat persepsi pasien pengguna dalam penggunaan aplikasi SIPRAJA untuk mengetahui permasalahan yang terjadi adalah PIECES Framework. Penelitian ini merupakan penelitian kualitatif deskriptif. Penelitian ini bertujuan untuk mengetahui gambaran persepsi pasien pengguna terhadap fitur reservasi rawat jalan pada aplikasi SIPRAJA di Rumah Sakit Bhayangkara Denpasar. Penelitian dilakukan dengan melakukan wawancara pada 16 pengguna aplikasi SIPRAJA. Hasil penelitian diperoleh bahwa kinerja fitur reservasi rawat jalan baik, informasi yang sesuai, memberikan keuntungan ekonomi, keamanan perlu ditingkatkan, sudah mempercepat proses pendaftaran, dan pelayanan mudah. Penerapan fitur reservasi rawat jalan sesuai dengan prosedur pertukaran data sistem antrian online oleh Ditjen Pelayanan Kesehatan dan standar penerimaan pasien yang ditetapkan oleh Rumah Sakit Bhayangkara Denpasar. Persepsi pasien pengguna terhadap fitur reservasi rawat jalan berdasarkan aspek PIECES baik. Pengguna puas dengan adanya fitur reservasi rawat jalan.
Kata Kunci: Pendaftaran rawat jalan, persepsi pengguna, PIECES Framework
 
ABSTRACT
The demand for outpatient services is increasing. Bhayangkara Denpasar Hospital has implemented an online registration system with the outpatient reservation feature on the SIPRAJA application as an effort to improve service. However, there are still long queues at the registration counter. One method to see patient user perceptions in using the SIPRAJA application to find out the problems that occur is the PIECES Framework. This research is a descriptive qualitative research. This study aims to describe the patient's perception of the outpatient reservation feature on the SIPRAJA application at Bhayangkara Hospital, Denpasar. The research was conducted by conducting interviews with 16 users of the SIPRAJA application. The results showed that the performance of the outpatient reservation feature is good, the information is appropriate, provides economic benefits, security needs to be improved, has accelerated the registration process, and easy service. The implementation of the outpatient reservation feature is in accordance with the online queuing system data exchange procedure by the Directorate General of Health Services and patient acceptance standards set by Bhayangkara Denpasar Hospital. User patient perception of the outpatient reservation feature based on the PIECES aspect is good. Users are satisfied with the outpatient reservation feature.
Keywords: Outpatient registration, user perception, PIECES Framework
HAMBATAN IMPLEMENTASI PROGRAM RUJUK BALIK DI FASILITAS KESEHATAN RUJUKAN TINGKAT LANJUT BADAN PENYELENGGARA JAMINAN SOSIAL KESEHATAN CABANG DENPASAR
Authors: Cindy Elisya Intan Larasati Putu , Sinthya Ulandari Luh Putu
Published: January 2025

ABSTRAK
Data BPJS Kesehatan Cabang Denpasar menunjukkan penyakit kronis kecil dan lain-lain menempati urutan pertama dalam 10 CBG’s terbanyak pada pelayanan rawat jalan tingkat lanjut di FKRTL, dengan total 1.086.311 kasus dan biaya pembayaran klaim mencapai 148 milyar pada tahun 2022. Oleh karena itu berdasarkan Peraturan BPJS Kesehatan Nomor 1 Tahun 2014, dibentuklah program rujuk balik untuk merujuk kembali pasien kronis yang telah dinyatakan stabil oleh dokter kembali ke FKTP. Data BPJS Kesehatan Cabang Denpasar menunjukan rendahnya capaian beberapa rumah sakit di wilayah kerja KC Denpasar dengan presentase 0,0%. Penelitian ini merupakan penelitian kualitatif dengan pendekatan deskriptif. Teknik pengambilan informan secara purposive sampling dengan jumlah 13 informan. Penelitian ini dilakukan di 3 lokasi yaitu RSUD Wangaya, Klinik Utama NIKI Diagnostic Center, dan Kantor Cabang BPJS Kesehatan Denpasar. Penelitian ini menggunakan analisis tematik dan validasi data triangulasi sumber. Hasil penelitian menunjukan terdapat beberapa kendala dalam pelaksanaan PRB ditinjau dari input dan proses, diantaranya kurangnya komitmen dan koordinasi antar petugas, tidak dimanfaatkannya warning potensi PRB, dan pasien menolak di PRB. Saran yang diberikan adalah pembuatan SOP, sosialisasi, pengadaan obat di FKTP, dan membuat alur koordinasi.
Kata Kunci:  Program Rujuk Balik, Penyakit Kronis, FKRTL, BPJS Kesehatan Cabang Denpasar
 
ABSTRACT
Data from BPJS Kesehatan Denpasar District stated that minor chronic diseases and others is the first rank of 10 most CBG's in outpatient services at advance referral health facilities, with a total of 1,086,311 cases, and claim payments reached 148 billion in 2022. Through to BPJS Kesehatan Regulation Number 1 of 2014, established a referral program to referback chronic patient which has been declared stable by spesialistic doctor to first level health facilities. Data from BPJS Kesehatan Denpasar District stated that the achievements of several hospitals in Denpasar work area are low with a percentage of 0.0%.
   This research is qualitative with a descriptive approach. Informant collection technique was purposive sampling with total of 13 informants. This research was conducted in 3 locations, which is Wangaya Hospital, NIKI Diagnostic Center Clinic, and BPJS Kesehatan Denpasar District. This research uses thematic analysis and validation of source triangulation data. The results showed there were several obstacles in the implementation of BRP in terms of inputs and processes, including lack of commitment and coordination between officers, not utilizing potential BRP warnings, and patients refusing to join BRP. Suggestions given are making SOPs, socialization, the procurement of drugs at PHC and making coordination flow.
Keywords: Back Referral Program, Chronic Disease, Advance Referral Health Facilities, Social Security Agency of Health Denpasar district
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN DUKUNGAN SUAMI TEKAIT PERAWATAN BAYI BARU LAHIR DI UPTD. PUSKESMAS IV DENPASAR SELATAN
Authors: Dewi Widiastuti Ni Putu Gayatri , Widyanthini Desak Nym
Published: January 2025

Dukungan sosial suami merupakan aspek penting bagi penyesuain diri ibu dalam menjalani aktivitas serta peran baru dalam merawat bayi. Penelitian ini bertujuan untuk melihat faktor-faktor yang berhubungan dengan dukungan suami terkait perawatan bayi baru lahir. Penelitian berupa studi analitik observasional menggunakan desain cross-sectional. Sampel penelitian merupakan suami yang membawa bayinya usia 0-6 bulan melakukan imunisasi dasar di UPTD. Puskesmas IV Denpasar Selatan dengan besar sampel 100 responden. Proses pengambilan data digunakan teknik consecutive sampling dengan kuesioner. Analisis data menggunakan uji deskriptif dan uji Simple Regresi Logistic. Variabel bebas penelitian ini adalah usia, pendidikan, pekerjaan suami, pekerjaan istri, jumlah anak, situasi tempat tinggal dan pengetahuan. Variabel terikat yakni dukungan suami terkait perawatan bayi baru lahir. Hasil penelitian ini didapatkan suami dengan 1 anak berpeluang 2,42 kali lebih baik dalam membentuk dukungan suami yang baik terkait perawatan kepada bayi baru lahir (OR=2,42; 95%CI 1,08-5,44). Suami yang memiliki pengetahuan baik akan berpeluang 3,39 kali memberikan dukungan suami baik terkait perawatan bayi baru lahir (OR=3,39; 95% CI 1,46-7,85). Pihak layanan kesehatan diharapkan mampu meningkatkan keterlibatan suami melalui pemberian edukasi terkait perawatan maupun pengasuhan anak sehingga suami dapat memberikan dukungan penuh pada ibu maupun bayi.Kata kunci : Dukungan Suami, Perawatan Bayi Baru Lahir
HUBUNGAN PENGETAHUAN DAN SIKAP TENTANG KESEHATAN REPRODUKSI DENGAN PERILAKU SEKSUAL REMAJA SMA DI SEKOLAH ISLAM TERPADU KOTA DENPASAR
Authors: Nirwana Yolanda Theta , Widarini Ni Putu
Published: January 2025

Remaja menurut World Health Organization (WHO) yaitu individu berusia 10-19 tahun. Remaja menjadi kelompok berisiko tinggi tinggi secara seksual karena remaja berada pada fase perubahan secara fisik dan psikologi. Menurut SDKI 2017 kasus IMS di Indonesia tertinggi terjadi pada wanita belum menikah sebesar 20% rentang usia 15-19 tahun (21%). Pendidikan formal berperan dalam meningkatan pengetahuan dan perilaku seksual remaja. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan dan sikap remaja tentang kesehatan reproduksi dengan perilaku seksual remaja SMA di sekolah Islam Terpadu Kota Denpasar. Penelitian ini merupakan penelitian kuantitatif analitik dan pendekatan cross sectional. Teknik pengambilan sampel menggunakan Two Stage Random Sampling dengan jumlah sampel sebesar172 siswa kelas XII. Teknik analisis data menggunakan Binary Logistic Regression. Hasil penelitian menunjukkan remaja berpengetahuan rendah 118 (68,60%) dan 54 (31,40%) berpengetahuan tinggi, remaja dengan sikap positif 120 (69,77%) dan sikap negatif 52 remaja (30,23%), dan remaja seksual berisiko 131 orang (76,16%) dan tidak berisiko 41 remaja (23,84%). Hasil analisis uji multivariat menunjukkan tingkat pengetahuan remaja memiliki hubungan signifikan dengan perilaku seksual remaja (p-value< 0,001) dan sikap tidak memiliki hubungan yang signifikan dengan perilaku seksual remaja (p-value 0,05) setelah dikontrol oleh variabel lainnya.Kata Kunci : Pengetahuan, Sikap, Kesehatan Reproduksi, dan Perilaku Seksual
DETERMINAN KEJADIAN GANGGUAN SISTEM PERNAPASAN PADA PENGRAJIN DUPA DI PABRIK DUPA BUNGA WANGI SELEMADEG, TABANAN
Authors: Tresnawulandari Kadek Titin , Wirawan I Md. Ady
Published: January 2025

Penyakit Akibat Kerja (PAK) merupakan penyakit yang disebabkan oleh pekerjaan dan/atau lingkungan kerja. Berdasarkan data BPJS Ketenagakerjaan, tercatat sebanyak 1.123 kasus PAK di Indonesia, sementara dalam pertengahan tahun 2022 tercatat sebanyak 753 kasus PAK di Indonesia. Serbuk kayu yang digunakan dalam industri dupa menghasilkan debu yang menyebabkan gangguan sistem pernapasan. Tujuan penelitian ini mengetahui kejadian gangguan sistem pernapasan dan faktor-faktor yang memengaruhi gangguan sistem pernapasan pada pengrajin dupa di Pabrik Dupa Bunga Wangi Selemadeg, Tabanan. Penelitian ini bersifat kuantitatif analitik dengan desain cross sectional. Sampel berjumlah 23 orang. Pengumpulan data dilakukan melalui penyebaran kuesioner dan pengukuran spirometri yang kemudian dianalisis menggunakan Uji Mann-Whitney U Test dan Uji Binomial Logistic Regression. Hasil penelitian ini menunjukkan 91,3% responden mengalami keluhan gangguan sistem pernapasan dan 73,9% responden mengalami gangguan fungsi paru. Terdapat hubungan yang signifikan antara riwayat penyakit (p=0,015), kebiasaan merokok (p=0,009), perilaku penggunaan APD (p=0,041), dan persepsi terhadap lingkungan kerja (p=0,012) terhadap keluhan gangguan sistem pernapasan pada pengrajin dupa. Terdapat hubungan yang signifikan antara riwayat penyakit (p=0,035) terhadap kapasitas fungsi paru. Pihak pengelola sebaiknya membuat SOP, menyediakan APD bagi pekerja, dan menyediakan penyejuk udara di ruang kerja. Pekerja yang memiliki gangguan fungsi paru sebaiknya menggunakan masker dengan baik saat bekerja.Kata Kunci: Gangguan Sistem Pernapasan, Debu Kayu, Pabrik Dupa, Kapasitas Fungsi Paru
DETERMINAN KELELAHAN KERJA PADA PEKERJA SEBUAH HOTEL DI SANUR
Authors: Dewanthi Putu Natasya , Wirawan I Md Ady
Published: January 2025

Kelelahan kerja merupakan salah satu keluhan yang sering dialami oleh para pekerja akibat pekerjaan yang mereka lakukan. Ada beberapa faktor yang dapat meningkatkan risiko terjadinya kelelahan kerja, baik dari segi individu maupun pekerjaan itu sendiri. Penelitian ini bertujuan untuk mengidentifikasi faktor-faktor yang berkontribusi terhadap kelelahan kerja pada staf hotel di Sanur. Metode penelitian yang digunakan adalah penelitian kuantitatif dengan pendekatan analitik dan desain cross-sectional. Data dikumpulkan mulai Maret 2023 dari 54 staf hotel yang diambil sebagai sampel dengan menggunakan teknik total sampling. Kelelahan kerja diukur menggunakan skala penelitian Industrial Fatigue Research Committee (IFRC), sementara beban kerja fisik diukur dengan menggunakan kuesioner Physical Load Index (PLI). Analisis data dilakukan dengan menggunakan metode analisis univariat, bivariat, dan multivariat.Hasil analisis menunjukkan adanya hubungan antara beberapa faktor dengan kelelahan kerja pada staf salah satu hotel di Sanur, pada faktor pekerjaan yaitu bidang pekerjaan tepatnya bidang non-office (aOR=4,81; 95%CI=1,14-20,36; p=0,032) merupakan variabel yang paling berhubungan terhadap kejadian kelelahan kerja. Sebaiknya, pekerja ditempatkan pada bidang pekerjaan yang sesuai dengan kemampuannya. Memperhatikan kondisi pekerja saat bekerja pada bidang pekerjaannya masing-masing. Memberikan jam istirahat yang cukup pada pekerja.Kata Kunci: Kelelahan Kerja, Faktor Individu, Faktor Pekerjaan, IFRC, PLI
EXPERIENCE IN THE TREATMENT OF CONGENITAL INGUINAL HERNIAS IN CHILDREN AT THE DISTRICT CLINICAL HOSPITAL OF KHANTY-MANSIYSK
Authors:   Khanty-Mansiysk State Medical Academy, Zotin Andrey Vladimirovich ,   Regional Hospital of Khanty-Mansiysk autonomus District-Ugra, Yantsen Angelina Vladimirovna , Harizova Anastasiya Gennadievna ,   Regional Hospital of Khanty-Mansiysk autonomus District – Ugra
Published: January 2025

This article presents a comparative characteristic and evaluation of the results of surgical treatment of children with inguinal hernias, based on accumulated clinical material over the last 15 years on the basis of the KhantyMansiysk Regional Hospital.
ANALYSIS OF BODY WEIGHT DYNAMICS INDICATORS OF INFANTS DEPENDING ON THE TYPES OF BREASTFEEDING
Authors:   Surgut State University, Agaragimova Minakhanum Gadzhiagaevna , Dobrynina Olesya Dmitrievna
Published: January 2025

Physical development, especially in young children, is an indicator of nutritional adequacy. By the dynamics of the child's body weight we can judge whether the intake of nutrients into the body is sufficient or excessive. A survey was conducted among 127 mothers living in the city of Surgut, attached to polyclinic N, which included questions of monthly anthropometric indicators and details of child nutrition in the process of growth dynamics in the first year of life. According to the study, it revealed the reliable significance of body weight indicators depending on the type of feeding, as well as possible causes of non-harmonious development of children, which require close attention of a pediatrician
CHANGES IN HEMODYNAMIC PARAMETERS IN ELDERLY PATIENTS IN THE CLOSEST PERIOD AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT
Authors:   Khanty-Mansiysk State Medical Academy, Aysaev Nurdan Ulanbekovich , Molchanov Andrei Nikolaevich
Published: January 2025

The purpose of the work was to evaluate the hemodynamic results of transcatheter aortic valve replacement in elderly patients with aortic valve stenosis. Materials and methods: 58 medical records of patients with aortic valve stenosis aged 68.5 ± 2.6 years who underwent transcatheter aortic valve replacement were retrospectively analyzed. In the pre- and postoperative period, patients underwent a control echocardiography study. A comparative analysis of hemodynamic parameters of the heart was carried out in the absence of aortic valve stenosis in the immediate postoperative period. Conclusion: there was an unreliable decrease in the gradient on the aortic valve, changes in linear, volumetric parameters and left ventricular fraction.
THE CORRELATION ANALYSIS OF PLANTOGRAPHIC INDICES AND ANTHROPOMETRIC DATA OF CHILDREN IN TYUMEN REGION
Authors:   Tyumen State Medical University, Oskolkova Arina Romanovna , Zubik Grigoriy Vasilyevich , Orlov Sergey Aleksandrovich , Ahmatov Vladimir Nikolaevich , Juraev Juraboy Rahmatjonovich , Chiryatieva Tatyana Viktorovna
Published: January 2025

The formation of the arch of the child's foot is influenced by many factors and possible risk factors predisposing to the development of flat feet should be taken into account, because if the process of forming the arch of the child's foot went wrong, it will be much more difficult to correct it in an adult. One of the key factors in the development of children's flat feet is considered to be overweight. In pediatric orthopedics, the most promising method of diagnosing flat feet is light-optical computer plantography.
EFFECTIVENESS OF USING THE PREBIOTIC "MESI-VIT+" IN THE TREATMENT OF TYPE 2 DIABETES MELLITUS
Authors:   Department of Modern Methods of Diagnostics and Radiotherapy, Yasynova Aytan Yaver kizi
Published: January 2025

The ever-increasing prevalence of type 2 diabetes mellitus has served as the basis for the definition of this disease by WHO experts as an epidemic. Type 2 diabetes is a chronic disease characterized by impaired insulin secretion in the body and tissue sensitivity to it. The determining factor in the development of this pathology is dysfunction of beta cells of the pancreas. One of the factors inducing this process is a violation of the intestinal microflora. To date, innovative strategies are being developed in the treatment of type 2 diabetes, where the issues of correction of metabolic disorders through the modulation of the microbiota have become particularly relevant, since its role as a pathogenic factor of the metabolic syndrome is one of the most significant.
EPIDEMIOLOGICAL FEATURES OF MULTIPLE SCLEROSIS IN KHANTY-MANSIYSK AUTONOMOUS OKRUG – YUGRA
Authors:   Khanty-Mansiysk State Medical Academy, Mamedov Kanan Adil ogly , Sokolova Azalia Aysarovna
Published: January 2025

The continuing interest in epidemiological studies of multiple sclerosis (MS) is due to the constant dynamics of epidemiological indicators and attempts to identify modifiable risk factors for the development of the disease. Epidemiological features have been studied and factors affecting the risk of multiple sclerosis (MS) in the Khanty-Mansiysk Autonomous Okrug – Yugra have been identified.
CHONDROPROTECTIVE EFFECTIVENESS OF A COMBINATION OF CHONDROITIN SULPHATE AND GLUCOSAMINE (TERAFLEX) IN EXPERIMENTAL OSTEOARTHRITIS IN RATS
Authors:   Belarusian State Medical University, Turuta Yana Dmitrievna , Vauchok Aliaksandr Uladzimiravich
Published: January 2025

Using an experimental model of arthritis induced by intra-articular administration of monoioacetic acid in rats, it was found that daily administration of a combination of chondroitin sulfate and glucosamine in doses of 300/240 mg/kg, respectively, for 30 days led to a decrease in the area of destruction of the articular surface to 8%, and at a dose of 1000/ 800 mg/kg up to 3%. When differentially staining joint macropreparations with toluidine blue, it was revealed that teraflex at a dose of 1000/800 contributed to the appearance of a transparent substance on the eroded cartilage, stained in a color corresponding to hyaline. 17% of the surface of the hyaline cartilage of the joints of animals receiving placebo was covered with deep erosions. Under the same conditions, diclofenac at a dose of 10 mg/kg statistically significantly increased the area of the eroded surface of the cartilage to 29%; a total of 12 gastric ulcers were found in 4 out of 6 rats, receiving diclofenac.
REASONS FOR REMOVAL OF A TRANSPLANTED KIDNEY
Authors:   Belarusian State Medical University, Kubeko Andrei Vladimirovich , Shedko Yulia Aleksandrovna, , Dmitrieva Margarita Vladimirovna
Published: January 2025

We analyzed the morphological changes in the removed kidney allografts. The most common cause of the loss of function of the native kidneys was chronic glomerulonephritis (58%). The predominant pathology that led to transplantectomy was rejection of the graft (62.5%). Thrombosis of the transplant vessels was observed in 29.2%, and infectious complications in 16.7%.
AN INTEGRATIVE APPROACH IN THE DIAGNOSIS OF PREMENSTRUAL DYSPHORIC DISORDER
Authors:   Surgut State University, Kudrina Kristina Olegovna , Kuzmina Ildana Olegovna , Schelok Valeria Yuryevna
Published: January 2025

According to various data, premenstrual syndrome has a prevalence in the population from 6 to 80%. Premenstrual dysphoric disorder (PMDD) is the most severe form of premenstrual syndrome, which significantly affects a woman's quality of life, aggravating her physical, emotional and social condition. PMDD is difficult to diagnose and requires the attention of not only a general practitioner and an obstetrician-gynecologist, but also a psychotherapist. Difficulties in diagnosing this condition also consist in the fact that the targeted unified questionnaire on latent dysphoria has not been introduced into clinical medical practice in the Russian Federation.
Insônia e depressão: confluências neurobiológicas e tratamento
Authors: Zanini Márcio Andrei , Pinna Camilla Moreira de Sousa , Lourenço Rafael Brandes , Reis Flavia Zuccolotto dos , Borges Daniel Guilherme Suzuki , Santana Glícia Prates , Margis Regina , Tavares Júnior Almir Ribeiro
Published: January 2025

Introdução:  A relação bidirecional entre sono e depressão é amplamente conhecida e descrita na literatura, bem como observada na prática clínica. A insônia, além de fazer parte dos critérios diagnósticos da depressão, se apresenta como um fator de risco para episódio depressivo, prediz menor resposta ao tratamento, aumento do risco de recidivas e associa-se a uma maior gravidade do quadro em pacientes com transtorno depressivo. Para um tratamento adequado se faz fundamental o entendimento dessas entidades e os aspectos envolvidos neste cenário.  Método: Trata-se de uma revisão narrativa acerca da relação entre insônia e depressão, englobando fatores neuroquímicos, moleculares, cronobiológicos e epidemiológicos, articulando-se com a terapêutica disponível atualmente. Resultados:  Insônia e depressão compartilham anomalias em alguns sistemas neurotransmissores e vias cerebrais. A hiperatividade do sistema ativador reticular ascendente (SARA) é comum a ambas as condições. Alterações no ritmo circadiano e em parâmetros polissonográficos também são encontradas em indivíduos com quadro depressivo. Ainda, estudos epidemiológicos demonstram que a depressão é um importante preditor de insônia de forma recíproca. Conclusões: Com base nas diversas confluências fisiológicas, moleculares, genéticas e psicológicas, insônia e depressão se influenciam mutuamente. O uso das ferramentas farmacológicas e não farmacológicas com foco no manejo eficaz destas duas condições se faz mandatório para redução da gravidade e cronificação global do quadro, objetivando legítimo êxito no tratamento.
Comparative analysis of stress distribution in implant attachment versus cantilever prostheses
Authors: Neghab Saghar , Kouchehbaghi Kasra , Salehizeinabadi Mehdi , Yousefimanesh Hojatollah
Published: January 2025

Objectives:

Dental implants are essential for replacing missing teeth, but anatomical constraints can result in implant sites being distant from adjacent teeth. Cantilever implant prosthetics offer an alternative solution by bridging this gap. This study compares the efficacy of cantilever implant prosthetics with conventional implant placement directly adjacent to teeth.

Material and Methods:

Using cone beam computed tomography, 3-D models were constructed to accurately represent the anatomy of teeth 4, 5, and the surrounding jawbone. Two models were examined: (1) a pontic with a cantilever implant abutment and (2) a pontic connected to both an implant and a tooth abutment. Simulation testing applied forces of 100 Newton in vertical, horizontal, and 45° directions to mimic functional loads on anterior teeth. Analytical processes were conducted using specialized finite element analysis software.

Results:

In model 1, tension levels under a 100 N force at a 45° angle were 80.1 in the implant and 66.5 in the implant’s crown. In model 2, tensions decreased to 58.26 in the implant and 35.8 in the crown under the same conditions. Connecting the tooth to the implant significantly reduced the load on both components, indicating potential biomechanical benefits.

Conclusion:

The attachment of dental implants to adjacent teeth presents a suitable alternative for patients with challenging anatomical considerations.
Gram-Scale Photocatalysis with a Stable and Recyclable Chromium(III) Photocatalyst in Acetonitrile and in Water
Authors: Sittel Steven , Neuner Julian , Grenz Jonas , Förster Christoph , Naumann Robert , Heinze Katja
Published: January 2025

The use of stable photosensitizers made on a multigram-scale from cheap and available starting materials offers an extraordinary opportunity to translate small-scale proof-of-concept photoreactions to widespread applications in non-specialized laboratories, thereby promoting the implementation of light-driven syntheses. Herein, we report an easy, multigram-scale preparation of the exceptionally photo- and redoxstable chromium(III) complex [Cr(tpe)2]3+ (tpe = 1,1,1-tris(pyrid-2-yl)ethane) at room temperature. This photocatalyst was successfully employed in acetonitrile and in the “green” solvent water as demonstrated in visible-light induced Schenck-Ene reactions, Newman-Kwart rearrangements, radical cation Diels-Alder cycloadditions, oxidative decarboxylation and trifluoromethylation reactions with excellent substrate conversions and high turnover numbers. Gram-scale photocatalytic reactions were conducted using a simple round-bottom flask as reaction vessel and irradiation with energy-efficient blue LEDs or even with sunlight. The stable photocatalyst was successfully recycled in up to 90–92 % yields after the photoreactions.
Export And Economic Growth in Tanzania: Co-Integration and Causality Analysis
Authors: Tumaini J. W. , Bwana K. M.
Published: January 2025

Purpose: This study examines the co-integration and causal relationship between exports and economic growth in Tanzania using time series data from 1998 to 2018.
Design/Methodology/Approach: Gross Domestic Product (GDP) was employed to measure economic growth, while exports of all products (from agricultural, industrial, and mineral products) were extracted from country trade statistics and employed as the independent variables. Data analysis was done after some tests, such as stationary tests, co-integration, regression analysis, and Granger causality. The stationary test result suggested using unrestricted vector autoregressive (VAR) analysis, followed by the Granger causality test.
Findings: It revealed that those exports significantly influence Tanzania’s economic growth, which implies that an increase in exports provides the market for domestically produced goods and services and thus promotes more production and economic growth. The study further confirms that economic growth does not significantly influence exports from the country. However, it was further revealed that the causality between export and economic growth is not bi-directional.
Research Limitation: Historical data may not reflect current economic conditions. Hence, there were restricted degrees of freedom when adopting complex modelling.
Practical Implication: Promoting more exports will encourage domestic producers to increase production, eventually fuel economic growth.
Social Implication: The study recommends that policymakers develop strategies for increasing the diversity of exported products and local production capacity.
Originality/Value: The novelty lies in integrating Granger causality testing with cointegration analysis for Tanzania's trade context. These novelty aspects contribute to methodological advancement and practical understanding of Tanzania's economic dynamics, providing valuable insights for policy formulation and future research.
Artificial intelligence as a factor revolutionizing higher education
Authors: Melnyk Yuriy , Pypenko Iryna
Published: January 2025

The role of artificial intelligence-based chatbots in higher education
practice was considered. The use of chatbots among higher education
stakeholders (students and faculty) was studied. A model of stakeholder
behaviour was developed. This model describes two ways of solving
problems: with and without the use of artificial intelligence.
Trends in the use of chatbots in higher education were identified:
students were 26.9% more likely than faculty to use artificial
intelligence-based chatbots to prepare for classes or complete
assignments at their college/university; almost all students (68.0% of
68.3% who use chatbots) edited the results returned by generative
chatbots at their request; students were 30.1% more likely than faculty
to edit these results.
Kinesio Taping as a New Trend in Enhancing Anaerobic Power: A Narrative Review
Authors:   Institute of Health Sciences, İnönü University, 44000 Malatya, Türkiye, Ilbak Ismail
Published: January 2025

The purpose of this review was to examine the effects of KT on anaerobic power performance and to compile the methodologies and findings of the studies conducted in this field. The results of this research were compiled from studies meeting the predefined inclusion criteria, accessed through the keywords “Kinesio taping” and “anaerobic power” without a time limitation from the Web of Science, PubMed, and Google Scholar databases on 20.07.2024. The article selection process was carried out in accordance with the PRISMA diagram. As a result of the search, 22 articles were found. Considering the inclusion and exclusion criteria, a total of 18 articles were excluded, and 4 articles were included in the research. The results show that: 1) the participants were not athletes from any sports branch; 2) no power analysis was conducted to determine the sample size; 3) KT was only applied to quadriceps or hamstring muscle groups; 4) different techniques such as muscle facilitation technique, muscle inhibition technique, or I-shaped technique were used in KT application; 5) there was no standardization on the time interval between KT application and performance test; and 6) only the Wingate cycle ergometer test was used to determine anaerobic power. The conclusion of this research shows a consensus among researchers that KT increases anaerobic power regardless of the technique used, the time before the performance test, and the muscle it was applied to.
Web-based Panggung Lestari Village-Owned Enterprises (BUMDES) Integrated Service Information System
Authors: Fidiantoro Vicky , Rianto Rianto , Putri Puji Handayani
Published: January 2025

Village-Owned Enterprises (BUMDes) are village business institutions whose businesses are run by village communities and the village government to improve village welfare. BUMDes was formed as a business institution that can manage various businesses according to the needs and potential of the village. However, BUMDes face challenges in managing their business, such as recording transactions and reports. This research is to design and implement a website-based BUMDes integrated service information system at BUMDes Panggung Lestari. This system design uses a programming language PHP with framework codeigniter and database MySQL. The system development method used is SDLC (System Development Life Cycle) model waterfall. The web-based BUMDes integrated service information system is very effective and efficient used by BUMDes for managing, monitoring and supervising business activities. This system is designed to include features for recording income transactions or business operational costs, as well as providing reports that can be used for analysis and evaluation of operational performance, and providing information services to the public regarding information about BUMDes.
Automated Testing to Evaluate Employee Attendance System Performance Using Gtmetrix
Authors: Hafizhah Nurul , Hidayat Ahmad Tri
Published: January 2025

The employee attendance system is an important component in human resource management that functions to efficiently record and monitor employee attendance. With the increasing reliance on information technology, it is essential to ensure optimal performance and a satisfying user experience. It is important for companies to ensure that this system functions well and responsively. This study aims to evaluate the performance of an employee attendance system through automated testing using the website performance analysis tool GTMetrix. By adopting automated testing using GTMetrix on this system to measure and analyze its performance, this research also offers an objective and efficient approach to identifying performance bottlenecks. The results of this research can serve as a reference for information system developers in designing and implementing a more optimal employee attendance system. In addition, the research also provides insights into the importance of optimizing website performance in the context of business applications. The results of the performance and structure testing analysis on this system using GTMetrix achieved an A grade with a performance score of 100% and a structure score of 100%. This research emphasizes the importance of automated testing as a tool to enhance and improve the performance of information systems, thereby meeting user needs and supporting more effective human resource management.
A produção de normalidades e a exclusão social da pessoa surda
Authors: Souza Déborah Costa de , Azevedo Thiago Augusto Galeão de
Published: January 2025

Ao longo da história da sociedade, a comunidade surda sofreu com diversas formas de preconceito e desaprovação social, e que o reconhecimento da língua brasileira de sinais (libras) é recente, por meio de políticas públicas educacionais vindas após a Constituição Federal de 1988 como identidade desses indivíduos,  que muitas vezes seguiram com estereótipos de deficientes e incapazes, colocados à parte da sociedade dita “normal”, e como pretexto de reabilitá-los para o convívio com os ouvintes, tiveram sua língua suprimida, sendo adotado aos mesmos o oralismo, como estratégia de forçá-los ao uso da fala. O presente artigo, portanto, tem como objetivo geral descrever a produção da anormalidade e normalidade como perspectiva de exclusão social da pessoa surda quanto ao direito à educação bilíngue, a partir da teoria de Michel Foucault, que leva a fatores de discriminação e exclusão social, os objetivos específicos são I- analisar os impactos trazidos pela construção de nomenclaturas de normalidade e anormalidade para aquisição do direito à educação bilingue às pessoas surdas nos dias atuais, II- verificar, por meio de pesquisa bibliográfica, com abordagem qualitativa, se as escolas regulares, que recebem esses alunos, atuam ou não como institutos de marginalização desses indivíduos. A pesquisa é estruturada em termos da problemática voltada ao questionamento que busca responder em que medida a construção de padrões de normalidade e anormalidade em sociedade impacta na violação de direito à educação de pessoas surdas, no acesso à educação básica. Para tanto, serão trazidos elementos gerais sobre educação bilíngue, padrões de normalidade e anormalidade que levam a violação desse direito.
Uma Campanha de vacinação infantil contra COVID-19
Authors: Silva Ferreira Nayara , Durães Andrade Álvaro , Bastos Santos Ian , Souto Pires Mariana , Almeida Guimarães Vitória América
Published: January 2025

Objetivo: Sensibilizar os responsáveis legais sobre a vacinação infantil contra a COVID-19 e garantir proteção do público alvo. Método: Trata-se de um estudo descritivo, do tipo relato de experiência, que contou com a atuação dos acadêmicos de medicina, no dia 9 de abril de 2022. A ação de imunização contra a COVID-19 foi realizada na Estratégia de Saúde da Família Maracanã III, situada em Montes Claros – MG. Resultado: Contamos com a imunização de 57 crianças contra o SarsCov2, sendo 32 meninos e 25 meninas, na faixa etária de 5 a 12 anos. Conclusão: A experiência vivenciada foi fundamental para promoção de saúde da comunidade e aperfeiçoou os conhecimentos dos acadêmicos envolvidos acerca da vacinação.
Desterritorialización de la costa quintanarroense: el caso de Playa del Carmen
Authors: Pinkus Rendón Miguel Angel , Gonzalez Ku Abril Monserrat , López Niquete Ashantti Vereniss
Published: January 2025

El territorio de Quintana Roo, México desde 1902 (fecha de creación), ha sido artífice de una gama de acontecimientos que han repercutido en la apropiación, uso y manejo de los bienes comunes naturales que tienen en su interior. Es por ello, que el presente artículo se aboca a analizar cuáles han sido las variaciones políticas, socioculturales, económicas y cómo éstas han impactado en la conformación del paisaje y la transformación en el vínculo con los bienes comunes naturales. En particular se analiza el caso de Playa del Carmen como ejemplo de lo sucedido en la costa oriental del estado. En este sentido, se puede vislumbrar que en las seis primeras décadas del siglo veinte la dinámica económica giraba en torno a la utilización de los elementos naturales maderables o no maderables (corte del chicle) sea por particulares, compañías explotadoras, ejidos o colectivos de estos. A partir de principios de los años setenta se da un cambio abrupto, que es cuando la política pública federal promueve al turismo como eje conductor del sistema económico, tomando en un  primer momento a Cancún como polo de desarrollo y posteriormente a finales del siglo XX a la Riviera Maya, lo que conlleva a un crecimiento urbano, cambios de uso del suelo y tenencia de la tierra. Este estudio pretende dar un panorama de la desterritorialización de las comunidades costeras desde la historia ambiental y oral.
Los orientales y el bosque tropical durante el Yucatán separatista (1839-1843)
Authors: Koyoc Kú José Ángel
Published: January 2025

El objetivo de este artículo es analizar la relación entre los combatientes irregulares denominados orientales y el bosque tropical de la Península de Yucatán entre los años de 1839 y 1843. Las fuentes utilizadas para realizar este artículo son en su mayoría partes de guerra e interrogatorios a oficiales mexicanos procesados por las acciones efectuadas durante la campaña. A través del análisis de esta relación podremos ver la forma en la que este periodo fue importante para que un contingente de combatientes yucatecos se adaptara a combatir entre la vegetación del bosque tropical y aprendiera a utilizar los recursos que podían obtener de él para conseguir sus fines militares. El bosque tropical, presente tanto en el oriente como en el occidente de la Península, propició que los orientales desarrollaran un tipo de combatir disperso entre la vegetación, lo que los distinguió de gran parte de las tropas yucatecas.
Riesgo y resiliencia en la frontera
Authors: Morado Macías César
Published: January 2025

Reseña del X Coloquio Internacional sobre la Historia del Noreste de Mexico y Texas
Evaluation of the Nutritional Value of Rice Crackers Made from Local Raw Rice and Rinuak Fish (Psilopsis sp)
Authors: Wellyalina Wellyalina , Aisman Aisman , Rahmadila Anindya
Published: January 2025

Rice crackers are snacks made from rice flour that have a crunchy texture, salty and savoury taste. Making rice crackers with local raw materials of brown rice and rinuak fish is expected to increase the quality of the food so that it can be a complementary food product. expected to be able to add to the quality of the food so that it can be a functional complementary food product. functional complementary food product. This study aims to determine the chemical properties and nutritional value of rice crackers made from red rice and rinuak fish. red rice and rinuak fish. This research was conducted using an exploratory method through laboratory experiments laboratory. The treatments used were the ratio of brown rice and rinuak fish and legumes. This treatment was carried out with 3 replications so that the results can be said to be valid. Research results.  The results showed that each brown rice crackers with the addition of rinuak fish and nuts have the advantage of their respective nutritional content on the rice crackers obtained. The making of brown rice crackers with the addition of rinuak fish and nuts can increase the content of nutritional value, physiological effects on the body, and diversification of complementary food products.
Contribution to Sustainable Development Goals (SDGs):SDG 3: Zero HungerSDG 3: Good Health and Well-BeingSDG 8: Decent Work and Economic GrowthSDG 12: Responsible Consumption and ProductionSDG 15: Life on Land
Problemas de Crescimento e Desenvolvimento
Authors: Rocha Alan Motta da , Campos Diogo Correa , Kashiwabara Tatiliana Geralda Bacelar
Published: January 2025

Distúrbios do crescimento tem por definição ser um grupo de comorbidades patológicas ou fisiológicas que podem afetar desde neonatos a crianças em todo o mundo. Sabe-se que o desenvolvimento humano parte de características anatômicas, metabólicas, hormonais e biológicas, que se iniciam no desenvolvimento e replicação celular e podem ter interferência de fatores ambientais, socioeconômicos e merecendo destaque: genéticos. Visto isso as alterações do crescimento resumem-se em qualquer disfunção que possa acarretar numa alteração na curva de crescimento no acometido.