bluuebunny/crossref_metadata_2025 huggingface dataset:
Sleep Duration, Sleep Quality, and Insomnia in Association With Self-Rated Health: A Systematic Review and Meta-Analysis
Authors: Amiri Sohrab
Published: July 2023

Background and Objective This study undertook a systematic review and meta-analysis of the relationship between sleep duration, sleep quality, and insomnia in association with self-rated health.Methods Studies that had examined the relationship between sleep duration, sleep quality, and insomnia with self-rated health were eligible. PubMed and Scopus were the two main databases for searching for studies related to this meta-analysis. The Google Scholar database as a source of gray literature was also searched by hand. This search was from the beginning of the formation of databases until the end of January 2022, and the search language was limited to articles published in English. The Effective Public Health Practice Project Quality Assessment Tool was used to assess the quality of studies. For this meta-analysis, odds ratio and 95% confidence interval were extracted or calculated. The pool of studies was processed by the random effects method.Results Twenty-six studies were included in this meta-analysis. Sleep duration of ≤ 8 hours per day (h/d) (odds ratio = 1.58 and 95% confidence interval = [1.41–1.77]) and sleep duration of > 8 h/d (odds ratio = 1.32 and 95% confidence interval = [1.17–1.50]) are associated with poor self-rated health. Poor sleep quality and insomnia are associated with poor self-rated health. Conclusions Sleep problems have a negative effect on self-rated health, and therefore, effective interventions can help improve sleep.
Immigrants and Citizenship Education in the Netherlands
Authors: ERDEN-BASARAN Ozlem
Published: July 2023

The Netherlands is a significant example of citizenship education for other countries because of its distinctive citizenship politics based on immigration, and sexuality politics. This critical review focuses citizenship education curriculum in the Netherlands and highlights an understanding of how politically constructed educational objectives might endanger or support social cohesion and the integration of immigrants. This review, which is based on relevant literature, concentrates on secondary-level citizenship education because that level places the most emphasis on teaching civic principles based on citizenship policies, which have an emphasis on sexuality politics, Dutch nationality, and the assimilation of non-Western immigrants into Dutch society. The critical review of the current practices shows that there are two reasons for the failure to teach civic values to immigrant children and to create a harmonious relationship between locals and immigrants: 1) There is an inadequate explanation of how sexuality politics is connected to Dutch nationality in the school curriculum. 2) The political structure does not acknowledge that immigrant youth have a positive perception of understanding that sexuality politics is a component of Dutch nationality because of their political interests. Given the arguments, this discussion suggests that citizenship education curricula should give enough coverage to terms and concepts that are used to teach civic values and should have boundaries between politics and civic values to support the inclusion of immigrant communities.
Duodenal injury: A challenging diagnostic enigma for clinicians
Authors: Thyyar M Ravindranath
Published: July 2023

The objective of the article is to familiarize clinicians with duodenal injury and to recognize timely intervention to prevent morbidity and mortality associated with such injury. Although uncommon, duodenal injury challenges a clinician’s ability to diagnose and treat it in a timely fashion to prevent any associated mortality. The retroperitoneal anatomy makes duodenal injury difficult to diagnose. However, a high degree of suspicion based on the mechanism of injury and appropriate, timely diagnostic study leads to the correct identification of injury to the duodenum. The specific treatment depends on the type of injury that is detected. In conclusion, early recognition, and timely intervention of duodenal injury leads to a successful outcome.
Chinese EAP teachers’ graduate-level English academic
Authors: Li Yongyan , Ma Xiaohao
Published: July 2023

In China, it has been widely recognized that graduate students urgently need to develop capabilities in engaging in academic communication at the international level, above all through writing and publishing their research in English. This educational need has stimulated the growth of EAP and the teaching of English academic writing (EAW) to graduate students across disciplines at Chinese universities. In this paper we report an interview-based study which focused on understanding Chinese emerging EAP teachers’ graduate-level EAW instruction and their endeavors of professional development (PD). Our study adds to the limited existing literature on EAP practitioners’ contextualized teaching practices and their professional development, and generates insights that can be drawn upon by EAP professionals in other contexts
‘Different’ and ‘distinct’ as markers of otherness
Authors: Dolón Herrero Rosana
Published: July 2023

The present study seeks to offer an understanding of how high-end hotel websites produce privilege, creating a sense of belonging and entitlement for their 4/5-star guests. The experience of tourism is intrinsically linked to embracing otherness, and as a reflection of this, hotel websites offer a characterization of cultural otherness in an attempt to make it resonate with the potential expectations of a socioeconomically privileged client. The study considers the question of what elements of experience of otherness the website will address, relying on a Critical Discourse Analysis perspective and drawing on Bourdieu’s notion of habitus as related to lifestyle, difference and distinction. Specifically, the words different and distinct are addressed in this study as markers of otherness and privilege. Based on Fairclough’s sociocultural approach, and specifically on Halliday’s transitivity system, the use of these words in clause construction patterns yields an understanding of how specific representations of reality revolving around the idea of otherness are built up. The research is corpus-driven and qualitative, its conclusions also offering some insight as to how hotel websites recreate forms of in-group similarity
Effect of umbilical cord mesenchymal stem cells with/without silymarin on apoptosis, immunomodulation, proliferation, and necrosis of HepG2 cells v1
Authors: not provided pauluskusnantouns
Published: July 2023

Background: Liver cirrhosis and liver cancer are the main problems of liver disease, and livercirrhosis is the 11th leading cause of death worldwide. Fibrosis is aprogressive process of liver disease before cirrhosis. Currently, stem cellsare designed to treat various conditions, including chronic liver disease. Stemcells can inhibit the progression of fibrosis based on their immunomodulation,anti-apoptotic and proliferative effects. Methods: This study was an in vitro experimental study. Mesenchymal stem cells (MSC)were taken from the umbilical cord of newborns. This study used the HepG2 cellline because it has the characteristics of hepatocyte cells. Cell lines weredivided into four groups[RJ1] . The examination was performed on Nuclear factorkappa B (NF-κB)[RJ2] , caspase-3, apoptosis, necrosis, and proliferation. Results: Mesenchymal stem cells have the effect of reducing NF-κB levels, increasing caspase-3levels, reducing necrosis events, and increasing proliferation in HepG2 cells.Combining mesenchymal stem cells with silymarin can increase caspase-3 levelsand reduce the incidence of necrosis in HepG2 cells. Conclusions: Mesenchymal stem cells can regulate immunomodulation, increase proliferation, reducenecrosis, and regulate apoptosis of HepG2 cells.
Rancang Bangun Animasi Storytelling Berbasis Projection Mapping sebagai Pengembangan Media Pembelajaran Digital Pada Mata Pelajaran Seni Budaya di SMP
Authors: Sari Intan Permata , Permana Fahmi Candra , Firmansyaha Feri Hidayatullah
Published: July 2023

Adanya wabah pandemi Covid-19 yang sudah berjalan 2 tahun terakhir, menuntut Guru dan siswa untuk lebih cepat beradaptasi dengan teknologi digital. Hal ini berkaitan erat dengan salah satu dari 17 tujuan TPB (Tujuan Pembangunan Berkelanjutan) yang telah ditetapkan, yaitu tentang Pendidikan Berkualitas dan dikaitkan juga pada tren global Digital Learning saat ini, serta dihubungkan pada Implementasi Kurikulum Merdeka yang menargetkan berbagai inovasi pemanfaatan Teknologi Infomasi dan Komunikasi. Sehingga perlu adanya pengembangan media pembelajaran digital sebagai inovasi pemanfaatan teknologi multimedia dalam konten pembelajaran yang dapat meningkatkan kualitas pendidikan. Metode yang digunakan adalah metode Design and Development Research. Hasil akhir penelitian ini adalah Rancang bangun Animasi Storytelling Berbasis Projection Mapping sebagai Pengembangan Media Pembelajaran Digital Pada Mata Pelajaran Seni Budaya di SMP Lab School UPI Cibiru sebagai kolaborasi penelitian antara dosen UPI dengan guru Labschool.
Ensiklopedia Tipografi Sebagai Media untuk Meningkatkan Pemahaman Terhadap Tipografi
Authors: Rinjani Dian , Sari Maya Purnama , Padmasari Ayung Candra
Published: July 2023

Typography is one of the important elements in a multimedia product design. It is impossible to learn the science of typography from one course. Many terms exist in typography and can be learned by students to increase their knowledge of typography. One way to make it easier to know these typographic terms can be obtained from the encyclopedia. But the encyclopedia for typography does not yet exist. Based on this, the research is expected to be able to compile data on existing typographic terms which are then summarized into an interesting typographic encyclopedia and can improve student learning in multimedia education. After collecting data in the literature, it was continued to design a good typographic encyclopedia book and the next step was tested on 84 Multimedia Education students at the University of Pendidikan Indonesia who were contracting typography courses at the Multimedia Education Study Program, Universitas Pendidikan Indonesia. From the results of the trial, it was concluded that, through a good typographic encyclopedia book design, students could learn more easily about typographic terms.
Perancangan Video Pembelajaran Permainan Kul Kuk Sebagai Upaya Pelestarian Permainan Tradisional Bali
Authors: Widiastuti Ni Made Dian , Iriani Ni Wayan , Kusuma Putu Sandra Devindriati
Published: July 2023

Permainan tradisional adalah permainan yang biasa dimainkan oleh anak-anak, karena dunianya adalah bermain dan penuh dengan imajinasi. Di balik gerakan, ucapan, dan alat-alat yang digunakan, tersirat makna simbolis yang bermanfaat bagi perkembangan emosi, kognitif, motorik dan sosial anak sebagai sarana belajar untuk menuju kehidupan di masa dewasanya. Dengan manfaat yang dimiliki kenyataannya tidak sejalan dengan eksistensinya saat ini di masyarakat. Pesatnya perkembangan permainan digital membuat posisi permainan tradisional semakin tergeser dan perlahan mulai ditinggalkan. Jenis permainan yang mulai tidak dikenal oleh masyarakat salah satunya adalah permainan Kul Kuk.  Oleh karena itu perlu adanya pengenalan kembali kepada masyarakat terkait permainan tersebut melalui media yang lebih menarik untuk anak-anak. Video pembelajaran adalah salah satu media yang dapat digunakan untuk membantu permasalahan yang terjadi. Penulis memberikan solusi dengan mengembangkan video pembelajaran permainan Kul Kuk  dengan menggunakan model pengembangan Four-D (define, design, develop,disseminate). Adapun fokus yang dibahas merujuk pada perancangan media video dengan langkah-langkah penyusunan materi, merencanakan konsep, membuat storyboard dan produksi.
Recruitment, retention, and adherence of family caregivers: Lessons from a multisite trial
Authors: Rueda Díaz Leidy Johanna , De Souza Guedes Erika , Lopes Monteiro da Cruz Diná de Almeida
Published: July 2023

Objective. To describe the recruitment, retention of family caregivers, and adherence to a telephone based intervention evaluated in a multi-site trial and provide recommendations for the design of future studies. Methods. A descriptive study based on a secondary analysis of a multi-site clinical development in Colombia and Brazil. Recruitment was measured by the number of participants eligible and consented. Retention was assessed by the percentage of participants with outcomesdata at two follow-ups. The intervention adherence was measured by the percentage of the caregiver who received the intervention.
Results. Of the family caregivers assessed, 63% were eligible, and 32.9% declined to be in the study for time restriction or no interest. In Colombia, the total retention rate of caregivers was 63.4% at the first follow-up and 48% at the second follow-up, while in Brazil was de 52.8% and 46.2%, respectively. At the end of the study, the sample comprised 28 and 70 caregivers in the intervention and control groups, respectively, for a retention rate of 47%. Of 104 family caregivers allocated to the intervention group, 42 (40.3%) received five sessions. Most reported not completing the Caregiver´s ActivityDiary.
Conclusion. The recruitment of family caregivers, participant retention, and adherence to the telephone intervention was unsuccessful. Future studies should apply an assessment tool during the recruitment of family caregivers and replace the term "caregiver" with  "care provider"; in the material involved in the research; define a retention protocol before starting the study and involve family caregivers in the design of the interventions.
Socio-family Factors Predictive of Adaptative Coping Post COVID-19 Pandemic in Nursing Students from a Private University
Authors: Velásquez Restrepo Luz Enith , Basto Hernández Gladys Judith , Muñoz Astudillo María Nelcy
Published: July 2023

Objective. To identify socio-academic and family functionality factors – communication, cohesion, and flexibility – as predictive stimuli of adaptive coping of nursing university students in the post-COVID-19 pandemic.
Methods. A cross-sectional descriptive study with stratified random sampling, with participation by 416 Nursing students from a private university in Pereira (Colombia), who answered a self-completed sociodemographic characterization survey, the Olson et al., communication scale, FACES III scale to assess family cohesion and flexibility, and the Calixta Roy CAPS scale to assess coping and adaptation capacity. Binary logistic regression and Hosmer-Lemeshow goodness-of-fit were performedto determine predictors of success, using SPSS v.26.
Results. The profiles of the participants showed a higher proportion of women (78.4%), ages between 21 and 30 years (57.5%), young people who study and work (60.1%), and those who have an academic session on Friday and Saturday (67.5%). Nursing students perceive that their families communicate efficiently and satisfactorily (85.8%), have strong cohesion with a tendency towards attachment (73.6%) and flexibility, show a tendency towards chaos (70.7%) and have adaptive coping (48.5%). The success predictors for adaptive coping were female sex (p=0.007), academic session Friday and Saturday (p=0.042), occupation, study, and work (p=0.026), socioeconomic strata 4.5 and 6 (p=0.041), good or very good communication (p=0.001), balanced family cohesion (p =0.048), and balanced family flexibility (p=0.039).
Conclusion. This study found that good family functionality and having adequate socioeconomic conditions were predictors of higher coping and adaptation capacity during the COVID-19 pandemic in the nursing students who participated in the study.
Smartphone addiction and its impact on quality of sleep and academic performance among nursing students. Institutional based cross-sectional study in Western Rajasthan (India)
Authors: Kalal Nipin , Sabari Vel N , Angmo Sonam , Choyal Sukhi , Bishnoi Sunaina , Dhaka Subeeta , Rulaniya Suman , Banswal Surbhi
Published: July 2023

Objective. To explore the smartphone addiction and its impact on quality of sleep and academic performance among the nursing students.

Methods. A descriptive cross-sectional study was conducted among the nursing students (n=160) in tertiary care teaching hospital in western Rajasthan (India) by using standardized Smartphone Addiction Scale Short Version (SAS-SV), the quality of sleep was assessed by standardized Pittsburg’s Sleep Quality Index scale (PSQI) and academic performance was assessed by self –made Academic Performance Scale.

Results. In this study 38.1 % students were having moderate smartphone addiction. The smartphone addiction is directly associated with hours daily spend on smartphone (p < 0.001), time check smartphone after wake up in the morning (p < 0.001), and frequency of smartphone pickups in a day (p=0.003) of students. The quality of sleep is inversely associated with duration of smartphone use (p=0.004), hours daily spend on smartphone (p=0.002), time check smartphone after wake up in morning (p=0.010), of students The academic performance is significantly associated with hours daily spend on smartphone (p=0.003), time check smartphone after wake up in morning (p=0.001), and frequency of smartphonepickups in a day (p=0.015) of students.

Conclusion: A high proportion of nursing students have moderate smartphone addiction. This addiction was associated with an increased risk of poor sleep quality and poor academic performance. Educational activities on the healthy use of smartphones are needed in the studied group.
Educational Interventions in Adults with Type 2 Diabetes Mellitus in Primary Health Care Settings. A Scoping Review
Authors: Castillo-Merino Yasmin Alejandra , Ospina-Ayala Camila , Esquivel Garzón Natalia , Rodríguez-Acelas Alba Luz , Cañon-Montañez Wilson
Published: July 2023

Objective. To synthesize the evidence of studies with educational interventions for adults with type-2 diabetes mellitus (DM2) in primary health care settings.
Methods. A scoping review was conducted following the recommendations by the Joanna Briggs Institute and by the PRISMA declaration. The protocol was registered in INPLASY20215009. The search was carried out in: MEDLINE (via PubMed), EMBASE, Web of Science, LILACS, and grey literature.
Results. Seventeen studies were included; most were randomized clinical trials of which 65% were conducted in high-income countries, and all the studies represented 5 656 participants. The results showed four big categories derived from educational interventions: therapeutic adherence (significant results on the satisfaction with the treatment); self-care and self-management in diabetes (improvement in self-efficacy, empowerment, and disease awareness); glycemic control in diabetes (significant results in reducing glycosylated hemoglobin); nursing and its role in the educational interventions on patients with DM2 (guidance in restructuring behaviors).
Conclusion. The findings of this review suggest that educational interventions on patients with DM2 within the setting of primary health care can impact positively on therapeutic adherence, self-control, and knowledge of the disease. Moreover, it was possible to identify the influence of multidisciplinary health teams, where the relevance of nursing professionals in the construction and implementation of educational interventions is evidenced in obtaining better health results.
Aplicación de la Teoría de la Conducta Planificada (TCP) en estudiantes universitarios
Authors: González Ruiz Lorena , Izquierdo Rus Tomás
Published: July 2023

El presente artículo constituye una revisión sistemática dirigida a conocer laaplicación de la Teoría de la Conducta Planificada (TCP) en el ámbito de losestudiantes universitarios de Educación. Para dar respuesta al objetivo propuesto,se parte de una introducción donde se centra el estado de la cuestión y se revisala literatura en torno a los modelos de acción planificada. En cuanto al método, seaplicaron estrategias de búsqueda, selección y extracción de datos cuyos resultados fueron analizados con el programa Atlas.ti v.9. Posteriormente, se presentan losresultados, mostrando instrumentos TCP que revelan actitudes de los universitariosen pro de ciertas conductas hacia la inclusión, el emprendimiento, el aprendizaje o lapráctica de ejercicio físico. Se concluye a favor del buen ajuste de las dimensionesde la TCP y la capacidad predictiva de la intención de conducta en estudiantesuniversitarios.
Family integrated care: new perspectives for neonatal care
Authors: Bueno Mariana , Vieira Ana Claudia Garcia , Bacchini Fabiana
Published: July 2023

Over the years, the highly technological environment of the Neonatal Intensive Care Units (NICUs) has allowed the survival of increasingly more premature and sick newborn infants. In parallel, physical distancing increased between hospitalized infants and their families, culminating with parents having restricted access to their children, limited to few daily hours of contact and interaction. However, this separation can negatively influence the recovery and development of the newborns and infants who remain hospitalized for extended periods of time. It is currently known that parents play a critical role in promoting positive health outcomes during hospitalization and after hospital discharge of these newborn infants.
Legal Regulation of the Mechanism of Implementation of Public Social Expenditures in the Russian Federation
Authors: Zabralova O. S.
Published: July 2023

The paper is devoted to examination of the legal regulation of the mechanism of implementation of public social expenditures in the Russian Federation. It is determined that the mechanism under consideration constitutes a system that includes a number of elements that are grouped into certain subsystems, including the regulatory subsystem, the principles of legal regulation of public relations that develop in the process of spending in the social sphere, the material basis of spending in the social sphere, the legal basis of social spending that include budget allocations, expenditure and budgetary obligations of public legal education, types of social expenditures, an institutional subsystem that includes subjects of legal relations arising in the process of implementing social expenditures. The paper draws special attention to the issues of codification of social legislation. As noted in the paper, this legislation is very mobile — new acts can be adopted to support certain segments of the population that were not previously covered by social protection measures; existing regulatory legal acts can be canceled when necessary, they may be amended due to the revision of criteria for the provision of social support measures, etc. In this regard, it is substantiated that, despite the fragmented nature, social welfare legislation, due to the peculiarities of regulated public relations, currently does not need codification at the federal level.
Human Life as a Priority Object of Protection under Criminal Law
Authors: Kochoi S. M.
Published: July 2023

The author of the paper proceeds from inviolability of the premise that a person’s life presides the hierarchy of values protected by criminal law. Recognition and actual consolidation of this provision is one of unconditional achievements adopted in the Criminal Code of the Russian Federation of 1996. However, a myriad of additions and amendments made to the Criminal Code of the Russian Federation after it entered into force raises the question of whether they do not call into question the postulate of human life as a priority object of criminal protection?

To answer this question, the paper substantiates the thesis that decisive indicators of assessing a person’s life as the most important object of criminal law protection take the place in the system of the Special Part of the Criminal Code of the Russian Federation, which the legislator has assigned to infringeent on life (primarily murder), and the grounds that are established by the General Part of the Criminal Code of the Russian Federation for imposing the strictest of all types of punishment (life imprisonment or death penalty). Based on these indicators, initially established in the Criminal Code of the Russian Federation, the author concludes that at the time of its entry into force, a human life was really at the top of the system of values and goods protected by the Criminal Code. However, at present this conclusion cannot be considered indisputable, since the Criminal Code of the Russian Federation has introduced other norms where the sanctions are stricter than the sanctions of the norm on murder, and the grounds for the appointment of life imprisonment now include not only encroachments on human life. The author proposes to construct sanctions norms — both newly introduced and already existing — in such a way that no crime can be punished more severely than murder. In addition, the author proposes to abandon the legislative and law enforcement practice of absorbing murder by qualifying elements of other crimes, bearing in mind that they should be qualified only cumulatively.
Public Danger: Problems of Definition
Authors: Ondar A.‑B. S.
Published: July 2023

A crime becomes a crime when the public danger is defined properly. The concepts of «public» and «danger» form the basis of the concept of public danger, which is an indicator for the criminalization  and decriminalization of an act. The paper provides a lexical and doctrinal analysis of the concept of public danger, its social significance and the problems of developing criteria for its definition in relation to the benefits and human rights. The historical analysis of public danger, its relevance and the need to enshrine it in the current Criminal Code of the Russian Federation require a more careful consideration of this concept. It is not only public danger that must be established in the criminal law, but the criteria for distinguishing between its degree and nature must also be clearly formulated. Timely and proper definition of public danger allows you to adequately treat criminalization and decriminalization without prejudice to society. The paper proposes the author’s definition of public danger.
Community Law (Lex Communitas) as a Modern Stage in the Lex Mercatoria Development
Authors: Mazhorina M. V.
Published: July 2023

The concept of the medieval lex mercatoria is experiencing a renaissance in the context of the global spread of information and communication technologies and the scaling of cyberspace. Globalization was replaced by networkization, which gave rise to the phenomena of networks, network communities, network communications, and network law. The author has chosen an appropriate research angle — a look at the lex mercatoria through the prism of the current network world order. This led to the conceptualization of lex communitas as «community law», which is the main object of the study. Lex communitas is considered as a modern historical form of lex mercatoria, mediating the non-state rule-making of international professional communities, the multiplying functional subsystems of which include lex informatica, lex sportiva, lex constructionis, lex petrolea, lex proprietas intellectualis, lex cryptographia, sustainable business law (sustainable business law), etc. Affiliation with one or another professional community is the basis for the application of the norms of lex communitas. This approach, in a sense, opens up prospects for posing the problem of the grounds for legitimacy, of ways to legitimize the norms of non-state regulation in the subject area of private international law. The concept of lex communitas correlates with how the modern system of resolving cross-border private law disputes is being transformed, increasingly moving to an extrajudicial plane: from international commercial arbitration to platform and decentralized systems. The paper attempts to identify certain features of the current stage of development of the lex mercatoria, the quantitative composition of the norms of which is rapidly multiplying in parallel with the ongoing qualitative changes in the system of regulation of cross-border private law relations.
Longitudinal study of coping strategies in first-time stroke patients: association with cognitive dysfunction, stroke site and depression
Authors: Savina Maria A. , Petrova Elisaveta A. , Koltsova Eugenia A.
Published: July 2023

BACKGROUND. Inadequate coping strategies are associated with affective disorders and poor quality of life in stroke survivors. Although coping strategies are determined by several non-modifiable factors they have been shown to change over time.
AIM. Longitudinal assessment of coping strategies and associated factors in patients with first-ever stroke.
MATERIAL AND METHODS. This study was a part of prospective observational study of a cohort of patients with first-ever stroke. Patients underwent standard psychiatric, neurological and cognitive assessment and CT. Patients without aphasia, severe fatigue, eye problems fulfilled the coping strategies indicator (Amirkhan J.H., 1990): 87 patients in the first week after stroke, 45 patients in the second week, 20 patients in 3 months, 21 patients in 6 months, 33 patients in 1 year after stroke. Non-parametric statistics were used.
RESULTS. Different coping strategies were not determined by age, gender and severity of neurological deficit; there were some correlations with educational level, work status, cognitive dysfunction, stroke volume and lesion location. There were differences in the use of coping strategies in the groups with different depression manifestations: in the group with depression manifestations in the early recovery period and later, coping strategies did not differ from the control group in the acute stroke period, but since the manifestation of depression the amount of avoidance strategies increased. In the group with pre-stroke depression, a significant increase in avoidance strategies was observed in the first week after the stroke.
CONCLUSIONS. The longitudinal study of coping strategies revealed that the use of coping strategies is a dynamic process determined by several modifiable and non-modifiable factors in combination. Coping strategies were not predictors of depression; on the contrary, depression seems to influence the choice of coping strategies.
Probability of change in diagnosis among adult patients diagnosed with childhood mental disorders
Authors: Gazizullin Timur R. , Mendelevich Vladimir D.
Published: July 2023

BACKGROUND. The problem of changing a psychiatric diagnosis is a reality.
AIM. To study the frequency and probability of changing the exposed patient at the age of psychiatric illness when moving under the supervision of a psychiatrist served by a large population.
MATERIAL AND METHODS. We analyzed 246 cases of patients who first applied to a psychiatrist in childhood (adolescence), then taken for consultative or dispensary registration. The study was follow-up in nature, was carried out with the help of the analysis of electronic databases of the RCPB. acad. V.M. Bekhterev of the Ministry of Health of the Republic of Tatarstan (Kazan), as well as by studying primary medical documentation (outpatient cards and case histories). The results of the study were processed on the basis of Statistica 6.0 and MS Excel 2020.
RESULTS. The main variants of the outcomes of mental disorders diagnosed in childhood of patients are described. It is shown that in more than half of clinical cases the confirmation of a psychiatric diagnosis at an early age is not final, and the issue of further diagnostic search remains unresolved and requires revision. Using the methods of multifactorial statistics, the main transnosological (dimensional) models of algorithms for the development of mental disorders are modeled.
Congenital organic hyperinsulinism associated with a variant in the ABCC8 gene. Description of a family case
Authors: Ivanov Dmitry O. , Ditkovskaya Lilaya V. , Turkunova Mariia E. , Suspitsin Evgeny N.
Published: July 2023

Hypoglycemia is the most common metabolic disorder occurring in early childhood, which can be the first, and sometimes the only symptom of a whole range of diseases. Etiology determines the characteristic clinical features of the course of hypoglycemic syndrome. Diagnosis is complicated by the fact that the clinical manifestations of hypoglycemia are variable and little specific. The main cause of persistent hypoglycemia in children of the first years of life is congenital hyperinsulinism.

Congenital hyperinsulinism is a hereditary disease characterized by inadequate hypersecretion of insulin by beta cells of the pancreas. Manifesting as a rule in the neonatal period, congenital hyperinsulinism is a great threat, both in terms of survival of patients with late diagnosis, and in terms of the risks of severe neurological complications with inadequate therapy of emerging hypoglycemia.

The article describes a family case of congenital organic hyperinsulinism associated with a rare heterozygous mutation in the ABCC8 gene, the early diagnosis of which allowed avoiding severe complications of the disease and timely prescribing adequate treatment. The clinical variability of the course of the disease in related patients was shown, which required a personalized approach to diagnosis and treatment.

Thus, early detection of hypoglycemia, clarification of its etiology, including with the help of molecular genetic analysis, timely drug therapy and monitoring of the state of carbohydrate metabolism, are important aspects in the treatment and supervision of patients with congenital hyperinsulinism and the prevention of severe neurological complications in them.
Cortisol concentration as a marker of adaptation processes in children with infectious mononucleosis at different periods of the disease
Authors: Fedorova Anna V. , Brus Tatiana V. , Vasiliev Andrei G. , Timchenko Vladimir N. , Tagirov Nair S.
Published: July 2023

BACKGROUND: Infectious mononucleosis is an acute infectious disease caused by EpsteinBarr virus. This virus replicates in B-lymphocytes but may be as well found in the epithelial cells of pharynx and parotid ducts. Its typical symptoms include fever, lymphadenopathy and herpetic angina, the endocrine system may also be involved in the pathologic process.
AIM: The aim of the study is the change in cortisol levels in children of different sex and age during the peak and convalescence of infectious mononucleosis caused by the EpsteinBarr virus.
MATERIALS AND METHODS: Under observation were 94 children aged 1 to 17 years, among them from 1 to 5 years 22%, from 5 to 10 years 39%, from 10 to 15 years 27%, from 15 to 17 years 12%, with a diagnosis of EpsteinBarr virus mononucleosis moderate severity. The diagnosis was made on the basis of clinical, anamnestic and laboratory data. Studies confirming the diagnosis were carried out in the laboratory of St. Petersburg State Pediatric Medical University. In addition to routine examinations (clinical minimum), determination of M- and G- antibody titers to the EpsteinBarr virus, detection of the EpsteinBarr virus genome in the blood by PCR, and determination of cortisol levels by enzyme-linked immunosorbent assay in blood serum.
RESULTS: In all age groups, the cortisol concentration during the peak period was higher than during the convalescence period. At the same time, in girls in groups from 6 to 10 years old and from 11 to 16 years old, this difference was significant (1045.19 111.10 versus 740.97 120.68 nM/l and 977.31 81.40 versus 735.48 113.04 nM/l respectively). In boys of all age groups, the differences were significant and amounted to 1211.30 128.36 versus 864.63 126.90 nM/l in the group from 1 to 5 years old, and 1066.76 39.01 versus 817,90 101,52 nM/l in the age group from 6 to 10 years old, in the age group from 11 to 16 years 950.14 101.54 versus 779.61 125.68 nM/l.
CONCLUSIONS: Changes in cortisol levels in children during the peak of infectious mononucleosis depend on the severity of the disease, the presence and nature of complications. The level of cortisol determines various options for adaptation to infectious mononucleosis.
The role of dermatoscopy in skin neoplasms diagnostics in children and adolescents
Authors: Kulyova Svetlana A. , Khabarova Rina I.
Published: July 2023

Information about the natural nevogenesis of pigmented skin lesions, evolutionary and morphological features in pediatric patients is still rare in the medical literature despite the progress in dermatooncology. Clinical examination or analysis with the naked eye of skin neoplasms carries a certain diagnostic information content. However, this method is much less informative compared to the use of an epiluminescent microscope. Dermoscopy of skin neoplasms is a non-invasive highly informative diagnostic method. Nowadays, the technique is widely used in the clinical practice of pediatric oncodermatologists. This painless diagnosis is ideal for a primary analysis of the morphological picture melanocytic or other skin neoplasms, malignancy risk assessment and determining the tactics of managing pediatric patients. The necessity for differential diagnosis the spectrum of skin neoplasms dictates a trend towards improving research methods and an age-adapted approach. The method of skin microscopy can be attributed to the methods of choice among those currently available. The history of method, diagnostic informativeness and detailed morphological characteristics of melanocytic skin neoplasms in children and adolescents are presented.
Machine-Generated Colon Class Numbers: Automatic Classification of Indian Literary Works in the Wikidata Environment
Authors: Halder Debkanta , Biswas Meghna
Published: July 2023

Wikidata is emerging rapidly as an omnipresent information space. The main objective of Wikidata is to create a structure to represent all human knowledge in many different languages. It is a free, Linked Open Dataset (LOD) that can interact with humans and machines and act as a bridge between them. Wikidata serves as a central repository for structured data of all other Wiki-based applications (like Wikipedia, Wikibooks, and Wikinews), integrating them into a coherent unit. It is a multilingual, collaboratively editable central repository of structured and linked open data. Interestingly, Wikidata is based on a facet-based linked open data approach like, the theory of facet analysis proposed by Ranganathan. The literary works available in Wikidata are linked with the author of the work, the language of the work, and other important attributes like genre, publication year, and so on. The author of the work has properties like, date of birth, occupation, native language, writing language, and so on. These faceted linked data elements of literary works can be joined together based on the rule base of the Colon Classification (6th edition). The synthesis of the Colon class number is therefore amenable to automation in the Wikidata environment by using a set of suitable JavaScripts (these JavaScripts are called gadgets in the Wikidata environment). One such gadget is CCLitBox, developed by Stefano Bargioni (a librarian) and Carlo Bianchini (a teacher in LIS). This research study explores the applications of CCLitBox in generating CC 6th edition-based class numbers for Indian literary works.
Effect of low thoracic erector spinae block on postoperative pain management in patients undergoing lumbar microdiscectomy surgery
Authors: BİRİCİK Ebru , KARACAER Feride , LAFLI TUNAY Demet , ILGINEL Murat Türkeün , OKTAY Kadir , ÜNLÜGENÇ Hakkı , GÜNEŞ Yasemin
Published: July 2023

Purpose: Lumbar disk hernia is very common reason for spinal surgery and usually treats with surgical interventions. The primary aim of this randomized controlled study was to determine the effect of low thoracic ultrasound guided erector spinae plane (ESP) block on postoperative pain management in lumbar microdiscectomy surgery.

Materials and Methods: Totally 42 adults scheduled for elective lumbar microdiscectomy surgery and assigned into two groups as Group ESP and Group Control. Anesthesia was induced with propofol 2mg/kg, rocuronium 0.6 mg/kg, fentanil 2µg/kg and maintained with total intravenous anesthesia (propofol 4-8 mg/kg/h and remifentanil 0.03-0.05 µg/kg/min), N2O/O2 mixture %60/40 for all patients. When patients were positioned at prone, ESP or sham block performed bilaterally. ESP performed with bupivacain 0.5% 15 mL+lidocain 2% 5 mL in ESP group and saline 20 mL for sham group at the T10 level of spine. The postoperative analgesia provided with morphine 0.1 mg/kg intravenously and diclofenac Na 75 mg intramuscularly at last 30 minutes of surgery for all patients. Postoperative visual analog scale (VAS) scores, meperidine requirements and patients’ satisfaction were recorded.

Results: There were significant differences between Group ESP and Group Control in meperidine requirement, VAS scores at rest and leg movement and patients’ satisfaction. Time to first analgesic need was median 62.5 min (interquartile range 5-180) in Group ESP and median 7.50 min (interquartile range 5-10) in Group Control.

Conclusion: ESP can significantly reduce postoperative pain scores (VAS at rest and leg movement), meperidine requirement and can provide better patients’ satisfaction, postoperatively.
Evaluation of sternocleidomastoid muscle cutaneous silent period in patients with cervical dystonia
Authors: KIR Hasan Hüseyin , YÜRÜTEN ÇORBACIOĞLU Betigül , TOKGÖZ Osman Serhat
Published: July 2023

Purpose: The aim of this study to examine the in changes inhibitory interneurons of the brainstem, which are likely to be involved in pathophysiology of cervical dystonia, using the cutaneous silent period(SP) method which is an inhibitor reflex.

Materials and Methods: SP latency and interval values were obtained from bilateral sternocleidomastoid (SCM) muscles of individuals in 20 patients with cervical dystonia and 25 healthy volunteers using superficial electrodes. SP parameters obtained were compared within and between groups. Furthermore, intra-individual correlation analysis was performed for SP parameters from bilateral SCMs of the individuals in both groups.

Results: The mean age of the patients participating in the study was 49.3 ± 14.7, and the control group was 48.0 ± 13.7. There was no statistically significant difference between the two groups in terms of age and gender. No significant difference was found in the comparison of SP parameters both within and between groups. There was a strong intra-individual correlation between SP latencies of bilateral SCMs of both patient and control groups. It was determined that the strongly positive intra-individual correlation between SP intervals also continued in the control group, whereas at patient group disappeared.

Conclusion: The loss of correlation between bilateral SCM SP durations in the dystonia group indicates that the abnormality in interneuron connections, which is thought to be present in dystonia, may actually be a loss of order. This “disorganization” may explain the discrepancies in the results of cutaneous SP studies in dystonia patients.
A new prognostic index associated with pathological complete response in rectal cancer
Authors: YETİŞİR Abdullah Evren , BÜYÜKŞİMŞEK Mahmut , OĞUL Ali , ÇİL Timuçin , BOZKURT DUMAN Berna
Published: July 2023

Purpose: Approximately half of rectal cancer cases are diagnosed at a locally advanced stage. It is important to identify biomarkers that can predict pathological complete response in patients undergoing surgery following neoadjuvant chemoradiotherapy.

Materials and Methods: This retrospective study included 205 patients with locally advanced rectal cancer who underwent surgery and adjuvant chemotherapy following neoadjuvant chemoradiotherapy. Inflammatory biomarkers were assayed in the complete blood count before neoadjuvant therapy.

Results: A pathological complete response was detected in 20.5% of the patients. The neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and pan-immune inflammation value were significantly lower in the pathological complete response (+) group than in the pathological complete response (-) group. The cut-off of the pan-immune inflammation value was ≤ 331.2, and this parameter had the best diagnostic performance of 90.4%.

Conclusion: Neoadjuvant chemoradiotherapy followed by surgery and adjuvant chemotherapy remains the standard treatment approach for rectal cancer. Since pathological complete response improves oncological outcomes, it is important to identify biomarkers that can predict pathological complete response in rectal cancer
Analysis of ease and usefulness of using google sheets in accounting assignment with technology acceptance model approach
Authors: Dharojah Eka Putry Wahyuning , Sedyati Retna Ngesti , Tiara Tiara
Published: July 2023

Abstrak: Pelaksanaan kegiatan pembelajaran akuntansi saat ini sudah mulai dilakukan dengan berbantuan aplikasi. Aplikasi yang digunakan sebaiknya adalah aplikasi yang dapat diterima oleh seluruh siswa karena hal tersebut akan memudahkan siswa dalam memahami materi pembelajaran. Penelitian deskriptif kuantitatif ini dilakukan dengan tujuan untuk mendeskripsikan tingkat penerimaan siswa terhadap penggunaan aplikasi Google Sheets dalam pembelajaran akuntansi. Sampel yang digunakan adalah sebanyak 143 siswa yang diambil menggunakan teknik sampel jenuh. Metode pengumpulan data adalah menggunakan angket, wawancara, serta dokumentasi yang kemudian dianalisis dengan teknik deskriptif persentase. Hasil penelitian menunjukkan bahwa siswa dapat menerima penggunaan aplikasi Google Sheets sebagai alat bantu mengerjakan tugas akuntansi karena aplikasi ini dinilai mudah dan bermanfaat untuk digunakan. Hal ini telah menyebabkan perolehan hasil belajar siswa menjadi maksimal. Dengan demikian, dapat disimpulkan bahwa penerimaan yang baik terhadap penggunaan suatu alat atau media pembelajaran akan memudahkan dalam pencapaian tujuan pembelajaran.Abstract: The implementation of accounting learning activities has now begun to be carried out with the help of applications. The application used should be an application that can be accepted by all students because this will make it easier for students to understand the learning material. This quantitative descriptive research was conducted with the aim of describing the level of student acceptance of the use of the Google Sheets application in accounting learning. The sample used was 143 students taken using the saturated sample technique. Data collection methods were by questionnaires, interviews, and documentation, which were then analyzed using percentage descriptive techniques. The results of the study show that students can accept the use of the Google Sheets application as a tool for doing accounting assignments because the application is considered easy and useful to use. This has led to the acquisition of student learning outcomes to be maximized. Thus, it can be concluded that good acceptance of the use of a learning tool or media will facilitate the achievement of learning objectives.