bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between genetic polymorphisms in the autophagy-related 5 gene promoter and the risk of sepsis
Authors: Shao Yiming , Chen Feng , Chen Yuhua , Zhang Wenying , Lin Yao , Cai Yujie , Yin Zihan , Tao Shoubao , Liao Qinghui , Zhao Jianghao , Mai Hui , He Yanfang , He Junbing , Cui Lili
Published: August 2017

Previous studies demonstrated significant roles of autophagy in the pathogenesis of sepsis, but few studies focused on the effect of autophagy-related SNPs on sepsis susceptibility. In this present study, five polymorphisms of ATG5/ATG16L1 were investigated for the possible risk on sepsis in a Chinese Han population. Our results showed that ATG5 expression levels decreased with the severity of sepsis, and rs506027 T > C and rs510432 G > A were associated with sepsis progression and mortality. Moreover, the rs506027 TT and rs510432 GG carriers also exhibited increased expression levels of ATG5. Functional assays showed that ATG5 knockdown elevated the secretion of pro-inflammatory cytokines in THP-1 cells, and the extracted mononuclear cell of the risk C-A carriers exhibited decreased ATG5 expression levels, leading to enhanced releases of TNF-α and IL-1β under LPS stimulation in vitro. Furthermore, ATG5 T-G haplotype mutation showed higher promoter activities compared to C-A haplotype mutation, suggesting the effect of these SNPs on ATG5 gene transcription. Taken together, these results above indicated that these two ATG5 promoter polymorphisms may be functional and clinically significant for sepsis progression, underscoring its potentially therapeutic implications for sepsis and other inflammatory diseases.
Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors
Authors: Mauro Concetta Di , Pesapane Ada , Formisano Luigi , Rosa Roberta , D’Amato Valentina , Ciciola Paola , Servetto Alberto , Marciano Roberta , Orsini Roberta Clara , Monteleone Francesca , Zambrano Nicola , Fontanini Gabriella , Servadio Adele , Pignataro Giuseppe , Grumetto Lucia , Lavecchia Antonio , Bruzzese Dario , Iaccarino Antonino , Troncone Giancarlo , Veneziani Bianca Maria , Montuori Nunzia , Placido Sabino De , Bianco Roberto
Published: August 2017

The urokinase-type plasminogen activator receptor (uPAR) is a GPI-anchored cell membrane receptor that focuses urokinase (uPA) proteolytic activity on the cell surface. Its expression is increased in many human cancers, including non-small cell lung cancer (NSCLC) and colorectal cancer (CRC), and correlates with a poor prognosis and early invasion and metastasis. uPAR is able to control, through a cross-talk with tyrosine kinase receptors, the shift between tumor dormancy and proliferation, that usually precedes metastasis formation. Therefore, we investigated the role of uPAR expression in RAS mutated NSCLC and CRC cells. In this study we provided evidence, for the first time, that RAS mutational condition is functionally correlated to uPAR overexpression in NSCLC and CRC cancer cell lines and patient-derived tissue samples. Moreover, oncogenic features related to uPAR overexpression in RAS mutated NSCLC and CRC, such as adhesion, migration and metastatic process may be targeted, in vitro and in vivo, by new anti-uPAR small molecules, specific inhibitors of uPAR-vitronectin interaction. Therefore, anti-uPAR drugs could represent an effective pharmacological strategy for NSCLC and CRC patients carrying RAS mutations.
SmartScope2: Simultaneous Imaging and Reconstruction of Neuronal Morphology
Authors: Long Brian , Zhou Zhi , Cetin Ali , Ting Jonathan , Gwinn Ryder , Tasic Bosiljka , Daigle Tanya , Lein Ed , Zeng Hongkui , Saggau Peter , Hawrylycz Michael , Peng Hanchuan
Published: August 2017

Quantitative analysis of neuronal morphology is critical in cell type classification and for deciphering how structure gives rise to function in the brain. Most current approaches to imaging and tracing neuronal 3D morphology are data intensive. We introduce SmartScope2, the first open source, automated neuron reconstruction machine integrating online image analysis with automated multiphoton imaging. SmartScope2 takes advantage of a neuron’s sparse morphology to improve imaging speed and reduce image data stored, transferred and analyzed. We show that SmartScope2 is able to produce the complex 3D morphology of human and mouse cortical neurons with six-fold reduction in image data requirements and three times the imaging speed compared to conventional methods.
Identification of NCAN as a candidate gene for developmental dyslexia
Authors: Einarsdottir Elisabet , Peyrard-Janvid Myriam , Darki Fahimeh , Tuulari Jetro J. , Merisaari Harri , Karlsson Linnea , Scheinin Noora M. , Saunavaara Jani , Parkkola Riitta , Kantojärvi Katri , Ämmälä Antti-Jussi , Yiu-Lin Yu Nancy , Matsson Hans , Nopola-Hemmi Jaana , Karlsson Hasse , Paunio Tiina , Klingberg Torkel , Leinonen Eira , Kere Juha
Published: August 2017

A whole-genome linkage analysis in a Finnish pedigree of eight cases with developmental dyslexia (DD) revealed several regions shared by the affected individuals. Analysis of coding variants from two affected individuals identified rs146011974G > A (Ala1039Thr), a rare variant within the NCAN gene co-segregating with DD in the pedigree. This variant prompted us to consider this gene as a putative candidate for DD. The RNA expression pattern of the NCAN gene in human tissues was highly correlated (R > 0.8) with that of the previously suggested DD susceptibility genes KIAA0319, CTNND2, CNTNAP2 and GRIN2B. We investigated the association of common variation in NCAN to brain structures in two data sets: young adults (Brainchild study, Sweden) and infants (FinnBrain study, Finland). In young adults, we found associations between a common genetic variant in NCAN, rs1064395, and white matter volume in the left and right temporoparietal as well as the left inferior frontal brain regions. In infants, this same variant was found to be associated with cingulate and prefrontal grey matter volumes. Our results suggest NCAN as a new candidate gene for DD and indicate that NCAN variants affect brain structure.
Bifidobacteria exert species-specific effects on constipation in BALB/c mice
Authors: Wang Linlin , Hu Lujun , Xu Qi , Jiang Tian , Fang Shuguang , Wang Gang , Zhao Jianxin , Zhang Hao , Chen Wei
Published: August 2017

Edible bifidobacteria exerted species-specific effects in relieving constipation.
Gelatin gels as multi-element calibration standards in LA-ICP-MS bioimaging: fabrication of homogeneous standards and microhomogeneity testing
Authors: Šala Martin , Šelih Vid S. , van Elteren Johannes T.
Published: August 2017

Fabrication of homogeneous multi-element gelatin standards for quantification purposes in 2D/3D LA-ICP-MS imaging and development of a microhomogeneity test.
A simple route to complex materials: the synthesis of alkaline earth – transition metal sulfides
Authors: Al-Shakban Mundher , Matthews Peter D. , O'Brien Paul
Published: August 2017

A simple, low-temperature synthesis of a family of alkaline earth metal chalcogenide thin films is reported.
Growth mechanism study of clustered aggregates of dirithromycin crystals in N,N-dimethylformamide solvent
Authors: Wang Yuan , Liang Zuozhong
Published: August 2017

A growth mechanism of novel clusters of the pharmaceutical compound dirithromycin was investigated by combining experimental crystallization and computational simulation.
A rapid scan vacuum FTIR method for determining diffusion coefficients in viscous and glassy aerosol particles
Authors: Zhang Yun , Cai Chen , Pang Shu-Feng , Reid Jonathan P. , Zhang Yun-Hong
Published: August 2017

The effect of glassy formation on water transport in sucrose aerosol droplets is evaluated from characteristic time in a vacuum FTIR experiment.
Imaging and chemically probing catalytic processes using field emission techniques: a study of NO hydrogenation on Pd and Pd–Au catalysts
Authors: Barroo Cédric , Moors Matthieu , Visart de Bocarmé Thierry
Published: August 2017

Nitric oxide hydrogenation is investigated on palladium and gold–palladium alloy crystallites,i.e.the extremity of sharp tip samples aimed at modelling a single catalytic grain.
Spiers Memorial Lecture: : Progress and prospects of reticular chemistry
Authors: Rungtaweevoranit Bunyarat , Diercks Christian S. , Kalmutzki Markus J. , Yaghi Omar M.
Published: August 2017

Reticular chemistry, the linking of molecular building units by strong bonds to make crystalline, extended structures such as metal–organic frameworks (MOFs), zeolitic imidazolate frameworks (ZIFs), and covalent organic frameworks (COFs), is currently one of the most rapidly expanding fields of science. In this contribution, we outline the origins of the field; the key intellectual and practical contributions, which have led to this expansion; and the new directions reticular chemistry is taking that are changing the way we think about making new materials and the manner with which we incorporate chemical information within structures to reach additional levels of functionality. This progress is described in the larger context of chemistry and unexplored, yet important, aspects of this field are presented.
A microfluidic oxygen gradient demonstrates differential activation of the hypoxia-regulated transcription factors HIF-1α and HIF-2α
Authors: Rexius-Hall Megan L. , Rehman Jalees , Eddington David T.
Published: August 2017

Gas control microfluidics demonstrate differences between HIF-1α and HIF-2α activation in a linear spatial oxygen gradient.
Quantitative correction of matrix effects in the determination of copper in human serum by isotope dilution quadrupole ICP-MS
Authors: Feng Liuxing , Wang Jun , Li Hongmei , Cui Yanjie , Lu Hai , Shi Naijie
Published: August 2017

Quantitative correction of matrix effects in the determination of Cu in human serum by using isotope dilution Q-ICP-MS.
Non-planar PDMS microfluidic channels and actuators: a review
Authors: Hwang Yongha , Candler Rob N.
Published: August 2017

Review of recent advances in fabrication of geometrically complex channels and actuators in PDMS, with a focus on 3D printing.
Design of transition-metal-doped TiO2as a multipurpose support for fuel cell applications: using a computational high-throughput material screening approach
Authors: Tsai Meng-Che , Rick John , Su Wei-Nien , Hwang Bing-Joe
Published: August 2017

Rapid screening using major descriptors suggests possible doping materials for developing TiO2-based support for the cathode in PEM fuel cells.
Magnetic cobalt ferrite nanoparticles CoFe2O4platform as an efficient sensor for trace determination of Cu(ii) in water samples and different food products
Authors: Mohamed Mona A. , El-badawy Fared M. , El-Desoky Hanaa S. , Ghoneim Mohamed M.
Published: August 2017

A novel electrochemical sensing platform using mesoporous nanoparticles for precise Cu determination is described.
Facile one-pot synthesis of 2-amino-1,3,4-oxadiazole tethered peptidomimetics by molecular-iodine-mediated cyclodeselenization
Authors: Santhosh L. , Srinivasulu C. , Durgamma S. , Prabhu Girish , Sureshbabu Vommina V.
Published: August 2017

Mild and highly efficient I2 and Et3N aided cyclodeselenization of in situ generated selenosemicarbazide is described to obtain 2-amino-1,3,4-oxadiazole peptidomimetics.
Nanoparticle discrimination based on wavelength and lifetime-multiplexed cathodoluminescence microscopy
Authors: Garming Mathijs W. H. , Weppelman I. Gerward C. , de Boer Pascal , Martínez Felipe Perona , Schirhagl Romana , Hoogenboom Jacob P. , Moerland Robert J.
Published: August 2017

Nanomaterials can be identified in high-resolution electron microscopy images using lifetime-selective cathodoluminescence.
Mammalian cell defence mechanisms against the cytotoxicity of NaYF4:(Er,Yb,Gd) nanoparticles
Authors: Sikora B. , Kowalik P. , Mikulski J. , Fronc K. , Kamińska I. , Szewczyk M. , Konopka A. , Zajdel K. , Minikayev R. , Sobczak K. , Zaleszczyk W. , Borodziuk A. , Rybusiński J. , Szczytko J. , Sienkiewicz A. , Wojciechowski T. , Stępień P. , Frontczak-Baniewicz M. , Łapiński M. , Wilczyński G. , Paszkowicz W. , Twardowski A. , Elbaum D.
Published: August 2017

Co-localization of UCNPs within cell organelles is shown.
In situ formation of luminescent CdSe QDs in a metallohydrogel: a strategy towards synthesis, isolation, storage and re-dispersion of the QDs
Authors: Chatterjee Sayantan , Maitra Uday
Published: August 2017

We describe a practical, one step, room temperature in situ synthesis of luminescent CdSe QDs using a bile salt derived metallogel, followed by their isolation from the gel and re-dispersion in an organic solvent.
Aqueous-solution-processable metal oxides for high-performance organic and perovskite solar cells
Authors: Lou Yan-Hui , Wang Zhao-Kui
Published: August 2017

Poly(3,4-ethylene dioxythiophene):poly(4-styrenesulfonate) (PEDOT:PSS) is a widely utilized hole-transporting material (HTM) in planar photovoltaic devices, such as organic solar cells (OSCs) and perovskite solar cells (PSCs).
Elucidating the role of surface passivating ligand structural parameters in hole wave function delocalization in semiconductor cluster molecules
Authors: Teunis Meghan B. , Nagaraju Mulpuri , Dutta Poulami , Pu Jingzhi , Muhoberac Barry B. , Sardar Rajesh , Agarwal Mangilal
Published: August 2017

An unprecedentedly large bathochromic-shift in the optical band of (CdSe)34 SCMs is observed upon passivating their surface with hole delocalizing ligands.
Transport properties of the top and bottom surfaces in monolayer MoS2grown by chemical vapor deposition
Authors: Kurabayashi S. , Nagashio K.
Published: August 2017

In this study, we investigated the interaction between monolayer MoS2and a SiO2/Si substrate and the difference in crystallinity between the top and bottom S surfaces due to the MoS2/substrate interaction.
The effects of polymer topology and chain length on the antimicrobial activity and hemocompatibility of amphiphilic ternary copolymers
Authors: Namivandi-Zangeneh Rashin , Kwan Rebecca J. , Nguyen Thuy-Khanh , Yeow Jonathan , Byrne Frances L. , Oehlers Stefan H. , Wong Edgar H. H. , Boyer Cyrille
Published: August 2017

Hyperbranched random copolymers that consist of ethylhexyl hydrophobic groups have the best selectivity compared to linear random and block copolymers.
A simple and general approach for the decoration of interior surfaces of silica hollow microspheres with noble metal nanoparticles and their application in catalysis
Authors: Ni Xinjiong , Hao Jiefu , Zhao Yaqian , Yang Cheng , Sun Peidong , Wang Chuanxi , Li Yunxing
Published: August 2017

Herein is reported a facile sacrificial template method to encapsulate noble metal nanoparticles with different sizes and compositions in silica hollow microspheres, which exhibit excellent catalytic activity and recyclability.
A thieno[3,4-b]thiophene-based small-molecule donor with a π-extended dithienobenzodithiophene core for efficient solution-processed organic solar cells
Authors: Liu Wuyue , Zhou Zichun , Vergote Thomas , Xu Shengjie , Zhu Xiaozhang
Published: August 2017

A molecular donor STB-4 with a dithieno[2,3-d′:2′,3′-d′]benzo[1,2-b:4′,5′-b′]dithiophene core was synthesized for organic solar cells with a power conversion efficiency of 8.17%.
Highly permeable and stable forward osmosis (FO) membrane based on the incorporation of Al2O3 nanoparticles into both substrate and polyamide active layer
Authors: Ding Wande , Li Yiming , Bao Mutai , Zhang Jianrui , Zhang Congcong , Lu Jinren
Published: August 2017

In the present study, hydrophilic Al2O3 nanoparticles were used as additives in both substrate and polyamide active (PA) layer to improve forward osmosis (FO) membrane properties.
Phillygenin attenuates inflammatory responses and influences glucose metabolic parameters by inhibiting Akt activity
Authors: Liu Wenjuan , Chu Guangcui , Chang Nianwei , Ma Xiaoyao , Jiang Min , Bai Gang
Published: August 2017

Phillygenin targets an allosteric inhibit pocket on Akt; alleviates inflammatory-associated downstream signal transduction factors and influences glucose metabolic parameters.
Low temperature catalytic hydrolysis of carbon disulfide over nano-active carbon based catalysts prepared by liquid phase deposition
Authors: Li Kai , Song Xin , Zhang Guijian , Wang Chi , Ning Ping , Sun Xin , Tang Lihong
Published: August 2017

Fe/nano-AC has good catalytic activity for CS2 hydrolysis. The activity of the catalyst was affected by the amount of pores (5–10 nm). Metal species affected the oxidation of H2S. The solution pH and fluoride affected the generation of Fe3+.
Evaluation of 4-alkoxy-4′-nitrobiphenyl liquid crystals for use in next generation scattering LCDs
Authors: Mandle Richard J. , Cowling Stephen J. , Goodby John W.
Published: August 2017

A combination of microscopy, X-ray scattering, calorimetry and applied electric field studies demonstrates the 4-alkoxy-4′-nitrobiphenyls are potentially of use for next generation, backlight free scattering mode LCD devices.
The fabrication of CdS/CoFe2O4/rGO photocatalysts to improve the photocatalytic degradation performance under visible light
Authors: Liu Xinlin , Qin Yingying , Yan Yongsheng , Lv Peng
Published: August 2017

A magnetic photocatalyst, CdS/CoFe2O4/rGO, has been successfully prepared via a simple hydrothermal method. The photocatalytic activity of the as-obtained composite photocatalyst was evaluated using the degradation of tetracycline.
Taking advantage of CTAB micelles for the simultaneous electrochemical quantification of diclofenac and acetaminophen in aqueous media
Authors: Guzmán-Hernández D. S. , Cid-Cerón M. M. , Romero-Romo M. , Ramírez-Silva M. T. , Páez-Hernández M. E. , Corona-Avendaño S. , Palomar-Pardavé M.
Published: August 2017

Cetyltrimethylammonium bromide hemimicelles, formed on the surfaces of a carbon paste electrode, selectively adsorbed diclofenac molecules from a neutral aqueous solution containing acetaminophen, allowing simultaneous quantification of both drugs.
Porous NiO–WO3 heterojunction nanofibers fabricated by electrospinning with enhanced gas sensing properties
Authors: Zhang Jinniu , Lu Hongbing , Liu Chang , Chen Chujun , Xin Xia
Published: August 2017

Porous NiO–WO3 heterojunction nanofibers with markedly enhanced sensing properties were fabricated by the electrospinning method.
Exploring sesquiterpene alkaloid-like scaffolds via Beckmann-transannular remodelling of beta-caryophyllene
Authors: Ma Shuang-Jiang , Yu Jie , Fan Hua-Fang , Li Zi-Han , Zhang An-Ling , Zhang Qiang
Published: August 2017

Cascaded Beckmann-transannular protocol transformed macrocyclic beta-caryophyllene into poly-heterocyclic unnatural skeletal types.
New methods for the preparation of nanoscale nickel phosphide catalysts for heteroatom removal reactions
Authors: Bussell Mark E.
Published: August 2017

Recent advances in the preparation of nickel phosphide (Ni2P) catalysts from hypophosphite-based precursors have resulted in high HDS and HDN activities.
Two-dimensional nanomaterials for photocatalytic CO2reduction to solar fuels
Authors: Chen Yong , Jia Gan , Hu Yingfei , Fan Guozheng , Tsang Yuen Hong , Li Zhaosheng , Zou Zhigang
Published: August 2017

In this study, we summarize a series of typical 2D nanomaterials for photocatalytic CO2conversion. Furthermore, based on the characteristics of 2D materials and the current status of research on photocatalytic CO2reduction, the challenges and opportunities of 2D materials as prospective photocatalysts for CO2reduction will also be discussed.
Structure of nanoscale-pitch helical phases: blue phase and twist-bend nematic phase resolved by resonant soft X-ray scattering
Authors: Salamończyk Mirosław , Vaupotič Nataša , Pociecha Damian , Wang Cheng , Zhu Chenhui , Gorecka Ewa
Published: August 2017

Periodic structures of phases with orientational order of molecules but homogenous electron density distribution: short pitch cholesteric phase, blue phase and twist-bend nematic phase, were probed by resonant soft X-ray scattering (RSoXS) at the carbon K-edge.
A novel supramolecular polymer gel based on naphthalimide functionalized-pillar[5]arene for the fluorescence detection of Hg2+and I−and recyclable removal of Hg2+via cation–π interactions
Authors: Lin Qi , Mao Peng-Peng , Fan Yan-Qing , Liu Lu , Liu Juan , Zhang You-Ming , Yao Hong , Wei Tai-Bao
Published: August 2017

By rationally applying cation–π interactions, the supramolecular polymer gel could successively detect Hg2+and I−and efficiently remove Hg2+from water.
Enzyme-embedded metal–organic framework membranes on polymeric substrates for efficient CO2 capture
Authors: Zhang Yiming , Wang Huixian , Liu Jindun , Hou Jingwei , Zhang Yatao
Published: August 2017

In this work, carbonic anhydrase (CA) molecules were embedded into metal–organic frameworks (MOFs) via physical absorption and chemical bonds, which could overcome the enzymatic inactivation and the poor separation property of pristine MOF materials.
Large scale green production of ultra-high capacity anode consisting of graphene encapsulated silicon nanoparticles
Authors: Kamali Ali Reza , Kim Hyun-Kyung , Kim Kwang-Bum , Vasant Kumar R. , Fray Derek J.
Published: August 2017

High quality graphene nanosheets produced in molten salts were found to be capable of wrapping silicon nanoparticles, leading to the fabrication of graphene encapsulated silicon nanoparticles with an excellent stable electrochemical performance as anode material for Li-ion batteries.
Efficient removal of Pb(ii) from water using magnetic Fe3S4/reduced graphene oxide composites
Authors: Kong Long , Li Zhichun , Huang Xueqiong , Huang Shouqiang , Sun Hua , Liu Min , Li Liang
Published: August 2017

Magnetic Fe3S4/rGO was prepared by the in situ sulfuration of Fe3O4/rGO, which showed much greater Pb(ii) removal performance than pristine Fe3O4/rGO.
Visible-light responsive MOF encapsulation of noble-metal-sensitized semiconductors for high-performance photoelectrochemical water splitting
Authors: Dou Yibo , Zhou Jian , Zhou Awu , Li Jian-Rong , Nie Zuoren
Published: August 2017

A strategy to utilize visible-light responsive MOFs as a protective shell over noble-metal-sensitized semiconductors to fabricate photoanode catalysts is developed. The resulting composites demonstrate outstanding performances in photoelectrochemical water splitting.
Miniaturised circularly‐polarised antenna with high‐constitutive parameter substrate
Authors: Farahani M. , Akbari M. , Nedil M. , Sebak A.R. , Denidni T.A.
Published: August 2017

A two‐dimensional (2D) high‐constitutive parameter (TDHCP) substrate is designed using an artificial metamaterial with high‐constitutive parameters. The planar TDHCP substrate is used for miniaturising of a circularly‐polarised microstrip patch antenna. A 2D metamaterial unit cell is needed due to the fact that the electric and magnetic vectors are rotating in a circularly‐polarised antenna. The proposed TDHCP substrate increases the constitutive parameters of the host substrate. It is composed of periodic split‐ring resonators loop circuits embedded in a low dielectric host medium. The TDHCP substrate provides equal permittivity and permeability () at any frequency of interest, which compensates for the bandwidth reduction due to the increased permittivity. The size of the proposed TDHCP substrate antenna at 850 MHz is reduced up to about 72% compared to the conventional microstrip patch antenna. The bandwidth of the antenna is increased compared to high‐electric permittivity substrates because of the increased the magnetic permeability. The proposed antenna is fabricated and measured. The simulated and measured results show a good agreement.
Detecting outdoor coexistence as a proxy of infectious contact through magnetometer traces
Authors: Kuk S. , Jeon Y. , Kim H.
Published: August 2017

If epidemic contact detection using smartphones can be done with sufficiently fine resolution in outdoor environments, so that those who were within the transmissible distance from an infected person may be identified as a potential infected is explored. The smartphone GPS, at least in its current capacity, is not useful to determine the coexistence within a couple meters that is critical for infectious disease transmission is shown. As an alternative, the usage of magnetometers is proposed, which enables the coexistence determination with the required precision, with much less energy consumption than GPS, and with an added bonus of indoor usability.
DEM’AUDIO : Création et validation d’un test de repérage de la presbyacousie adapté aux patients atteints de la maladie d’Alzheimer
Authors: BARRIERE Clémence , BOUDEELE Pauline
Published: August 2017

De nombreuses études démontrent actuellement un lien signifi catif entre la presbyacousie et les maladies neurodégénératives. Afi n de
détecter la presbyacousie le plus précocement possible, plusieurs tests auditifs ont été créés, mais ils ne prennent pas en compte les
troubles particuliers des patients atteints de maladie neurodégénérative.
Nous avons donc créé un test de repérage de la presbyacousie adapté aux patients atteints de la maladie d’Alzheimer. Celui-ci se
compose de quatre épreuves de répétition : répétitions de mots et de syllabes dans le calme et répétitions de mots et de syllabes dans
le bruit. Une épreuve alternative a été créée pour les patients atteints de troubles articulatoires. Cette dernière consiste à désigner
parmi plusieurs images le bruit du quotidien entendu. Plusieurs adaptations ont été mises en place afi n que les sujets atteints de la
maladie d’Alzheimer puissent réaliser notre test dans son entièreté. Un travail de validation de nos épreuves et de leurs adaptations a
été amorcé auprès de 48 sujets atteints de la maladie d’Alzheimer. Enfi n, une population de 7 sujets atteints de la maladie d’Alzheimer
a été composée dans le but de vérifi er une amélioration des scores au test lors du port d’appareils auditifs.
L’orthophonie pour soutenir le patient dans son appareillage :
adaptation, localisation et compréhension dans le bruit
Authors: Belouard Yannick
Published: August 2017

L’entrainement auditif proposé par l’orthophoniste doit faciliter l’appareillage du patient, et répondre aux diffi cultés rencontrées. En
complément de la lecture labiale, des exercices d’adaptation à l’appareillage, de localisation et de compréhension dans bruit peuvent
être proposés en tant que rééducateur. Cette prise en charge détaillée et illustrée cliniquement permet de mettre en évidence l’intérêt
d’une interdisciplinarité en audiologie.
Étiologies des surdités de transmission de l’enfant
Authors: MOM Thierry
Published: August 2017

La surdité de transmission de l’enfant est un diagnostic diffi cile. Elle peut passer inaperçue pendant plusieurs années et pourtant son
retentissement sur le développement langagier oral est possible à partir de 30 dB de perte auditive. Les étiologies sont nombreuses.
Il est utile de les classer en fonction de l’âge d’une part et de l’aspect tympanique d’autre part. Chez le nourrisson, les atteintes
malformatives prédominent. De deux à 6 ans l’otite séromuqueuse est de loin la cause la plus fréquente. Après 6 ans, on est plus
souvent confrontés à des séquelles d’otites répétées ou d’otite séromuqueuse. L’aspect tympanique est très informatif, notamment chez
l’enfant plus grand sans malformation apparente. Il permet de diagnostiquer rapidement les séquelles d’otite chronique, les aspects
malformatifs tympaniques éventuels, ou au contraire d’évoquer une surdité de transmission à tympan normal.
Temperature dependence of the hydrated electron’s excited-state relaxation. I. Simulation predictions of resonance Raman and pump-probe transient absorption spectra of cavity and non-cavity models
Authors: Zho Chen-Chen , Farr Erik P. , Glover William J. , Schwartz Benjamin J.
Published: August 2017

We use one-electron non-adiabatic mixed quantum/classical simulations to explore the temperature dependence of both the ground-state structure and the excited-state relaxation dynamics of the hydrated electron. We compare the results for both the traditional cavity picture and a more recent non-cavity model of the hydrated electron and make definite predictions for distinguishing between the different possible structural models in future experiments. We find that the traditional cavity model shows no temperature-dependent change in structure at constant density, leading to a predicted resonance Raman spectrum that is essentially temperature-independent. In contrast, the non-cavity model predicts a blue-shift in the hydrated electron’s resonance Raman O–H stretch with increasing temperature. The lack of a temperature-dependent ground-state structural change of the cavity model also leads to a prediction of little change with temperature of both the excited-state lifetime and hot ground-state cooling time of the hydrated electron following photoexcitation. This is in sharp contrast to the predictions of the non-cavity model, where both the excited-state lifetime and hot ground-state cooling time are expected to decrease significantly with increasing temperature. These simulation-based predictions should be directly testable by the results of future time-resolved photoelectron spectroscopy experiments. Finally, the temperature-dependent differences in predicted excited-state lifetime and hot ground-state cooling time of the two models also lead to different predicted pump-probe transient absorption spectroscopy of the hydrated electron as a function of temperature. We perform such experiments and describe them in Paper II [E. P. Farr et al., J. Chem. Phys. 147, 074504 (2017)], and find changes in the excited-state lifetime and hot ground-state cooling time with temperature that match well with the predictions of the non-cavity model. In particular, the experiments reveal stimulated emission from the excited state with an amplitude and lifetime that decreases with increasing temperature, a result in contrast to the lack of stimulated emission predicted by the cavity model but in good agreement with the non-cavity model. Overall, until ab initio calculations describing the non-adiabatic excited-state dynamics of an excess electron with hundreds of water molecules at a variety of temperatures become computationally feasible, the simulations presented here provide a definitive route for connecting the predictions of cavity and non-cavity models of the hydrated electron with future experiments.
Scanning SQUID sampler with 40-ps time resolution
Authors: Cui Zheng , Kirtley John R. , Wang Yihua , Kratz Philip A. , Rosenberg Aaron J. , Watson Christopher A. , Gibson Gerald W. , Ketchen Mark B. , Moler Kathryn. A.
Published: August 2017

Scanning Superconducting QUantum Interference Device (SQUID) microscopy provides valuable information about magnetic properties of materials and devices. The magnetic flux response of the SQUID is often linearized with a flux-locked feedback loop, which limits the response time to microseconds or longer. In this work, we present the design, fabrication, and characterization of a novel scanning SQUID sampler with a 40-ps time resolution and linearized response to periodically triggered signals. Other design features include a micron-scale pickup loop for the detection of local magnetic flux, a field coil to apply a local magnetic field to the sample, and a modulation coil to operate the SQUID sampler in a flux-locked loop to linearize the flux response. The entire sampler device is fabricated on a 2 mm × 2 mm chip and can be scanned over macroscopic planar samples. The flux noise at 4.2 K with 100 kHz repetition rate and 1 s of averaging is of order 1 mΦ0. This SQUID sampler will be useful for imaging dynamics in magnetic and superconducting materials and devices.
Near-field coupling of gold plasmonic antennas for sub-100 nm magneto-thermal microscopy
Authors: Karsch Jonathan C. , Bartell Jason M. , Fuchs Gregory D.
Published: August 2017

The development of spintronic technology with increasingly dense, high-speed, and complex devices will be accelerated by accessible microscopy techniques capable of probing magnetic phenomena on picosecond time scales and at deeply sub-micron length scales. A recently developed time-resolved magneto-thermal microscope provides a path towards this goal if it is augmented with a picosecond, nanoscale heat source. We theoretically study adiabatic nanofocusing and near-field heat induction using conical gold plasmonic antennas to generate sub-100 nm thermal gradients for time-resolved magneto-thermal imaging. Finite element calculations of antenna-sample interactions reveal focused electromagnetic loss profiles that are either peaked directly under the antenna or are annular, depending on the sample’s conductivity, the antenna’s apex radius, and the tip-sample separation. We find that the thermal gradient is confined to 40 nm to 60 nm full width at half maximum for realistic ranges of sample conductivity and apex radius. To mitigate this variation, which is undesirable for microscopy, we investigate the use of a platinum capping layer on top of the sample as a thermal transduction layer to produce heat uniformly across different sample materials. After determining the optimal capping layer thickness, we simulate the evolution of the thermal gradient in the underlying sample layer and find that the temporal width is below 10 ps. These results lay a theoretical foundation for nanoscale, time-resolved magneto-thermal imaging.
Structural and spectroscopic analysis of ex-situ annealed RF sputtered aluminium doped zinc oxide thin films
Authors: Otieno Francis , Airo Mildred , Erasmus Rudolph M. , Billing David G. , Quandt Alexander , Wamwangi Daniel
Published: August 2017

Aluminium doped zinc oxide thin films are prepared by Radio Frequency magnetron sputtering in pure argon atmosphere at 100 W. The structural results reveal good film adhesion on a silicon substrate (001). The thin films were then subjected to heat treatment in a furnace under ambient air. The structural, morphological, and optical properties of the thin films as a function of deposition time and annealing temperatures have been investigated using Grazing incidence X-Ray Diffraction (GIXRD), Atomic Force Microscopy, and Scanning Electronic Microscopy. The photoluminescence properties of the annealed films showed significant changes in the optical properties attributed to mid gap defects. Annealing increases the crystallite size and the roughness of the film. The crystallinity of the films also improved as evident from the Raman and XRD studies.
VUV spectroscopy in impurity injection experiments at KSTAR using prototype ITER VUV spectrometer
Authors: Seon C. R. , Hong J. H. , Song I. , Jang J. , Lee H. Y. , An Y. H. , Kim B. S. , Jeon T. M. , Park J. S. , Choe W. , Lee H. G. , Pak S. , Cheon M. S. , Choi J. H. , Kim H. S. , Biel W. , Bernascolle P. , Barnsley R.
Published: August 2017

The ITER vacuum ultra-violet (VUV) core survey spectrometer has been designed as a 5-channel spectral system so that the high spectral resolving power of 200–500 could be achieved in the wavelength range of 2.4–160 nm. To verify the design of the ITER VUV core survey spectrometer, a two-channel prototype spectrometer was developed. As a subsequent step of the prototype test, the prototype VUV spectrometer has been operated at KSTAR since the 2012 experimental campaign. From impurity injection experiments in the years 2015 and 2016, strong emission lines, such as Kr xxv 15.8 nm, Kr xxvi 17.9 nm, Ne vii 46.5 nm, Ne vi 40.2 nm, and an array of largely unresolved tungsten lines (14-32 nm) could be measured successfully, showing the typical photon number of 1013–1015 photons/cm2 s.
False star detection and isolation during star tracking based on improved chi-square tests
Authors: Zhang Hao , Niu Yanxiong , Lu Jiazhen , Yang Yanqiang , Su Guohua
Published: August 2017

The star sensor is a precise attitude measurement device for a spacecraft. Star tracking is the main and key working mode for a star sensor. However, during star tracking, false stars become an inevitable interference for star sensor applications, which may result in declined measurement accuracy. A false star detection and isolation algorithm in star tracking based on improved chi-square tests is proposed in this paper. Two estimations are established based on a Kalman filter and a priori information, respectively. The false star detection is operated through adopting the global state chi-square test in a Kalman filter. The false star isolation is achieved using a local state chi-square test. Semi-physical experiments under different trajectories with various false stars are designed for verification. Experiment results show that various false stars can be detected and isolated from navigation stars during star tracking, and the attitude measurement accuracy is hardly influenced by false stars. The proposed algorithm is proved to have an excellent performance in terms of speed, stability, and robustness.
Semi-rational solutions of the third-type Davey-Stewartson equation
Authors: Rao Jiguang , Porsezian Kuppuswamy , He Jingsong
Published: August 2017

General dark solitons and mixed solutions consisting of dark solitons and breathers for the third-type Davey-Stewartson (DS-III) equation are derived by employing the bilinear method. By introducing the two differential operators, semi-rational solutions consisting of rogue waves, breathers, and solitons are generated. These semi-rational solutions are given in terms of determinants whose matrix elements have simple algebraic expressions. Under suitable parametric conditions, we derive general rogue wave solutions expressed in terms of rational functions. It is shown that the fundamental (simplest) rogue waves are line rogue waves. It is also shown that the multi-rogue waves describe interactions of several fundamental rogue waves, which would generate interesting curvy wave patterns. The higher order rogue waves originate from a localized lump and retreat back to it. Several types of hybrid solutions composed of rogue waves, breathers, and solitons have also been illustrated. Specifically, these semi-rational solutions have a new phenomenon: lumps form on dark solitons and gradual separation from the dark solitons is observed.
Thermodynamics of atomistic and coarse-grained models of water on nonpolar surfaces
Authors: Ardham Vikram Reddy , Leroy Frédéric
Published: August 2017

In order to study the phenomena where interfaces play a dominant role through molecular simulations, the proper representation of the interfacial thermodynamic properties of a given model is of crucial importance. The use of coarse-grained rather than atomistic models makes it possible to simulate interfacial systems with larger time and length scales. In the present work, we compare the structure and thermodynamic behavior of one atomistic and two single-site coarse-grained models of water on nonpolar surfaces, namely, graphite and the basal plane of molybdenum disulfide. The three models interact with the surfaces through Lennard-Jones potentials parametrized to reproduce recent experimental contact angle measurements. The models form a layered structure close to the surface, which is usually observed on sufficiently attractive nonpolar substrates. However, differences in the structure and thermodynamic behavior are observed between the models. These differences are explained by certain features of the water models, such as short range tetrahedral order and liquid density fluctuations. Besides these results, the approach employed in the present study may be used to assess the ability of coarse-grained models for solid-liquid systems to represent consistent interfacial thermodynamics.
Wide (0001) terrace formation due to step bunching on a vicinal 4H-SiC (0001) epitaxial layer surface
Authors: Tabuchi Yuki , Ashida Koji , Sonoda Masashi , Kaneko Tadaaki , Ohtani Noboru , Katsuno Masakazu , Sato Shinya , Tsuge Hiroshi , Fujimoto Tatsuo
Published: August 2017

The wide (0001) terrace formation due to step bunching on a vicinal 4H-SiC (0001) epitaxial layer surface was investigated using low-energy electron channeling contrast (LE-ECC) imaging and atomic force microscopy. LE-ECC imaging revealed that step bunching resulted in the formation of wide atomically-flat (∼200 nm) (0001) terraces on the surface, and the terraces tended to form in pairs. Terraces in a pair had almost the same width and often showed the same LE-ECC; moreover, the contrast of the two terraces, either bright or dark, appeared to be determined by the orthogonal misorientation of substrates. On the basis of these results, the formation mechanism of the paired terraces with the same LE-ECC on a vicinal 4H-SiC (0001) surface is discussed herein.
Recent advances in estimating protein and energy requirements of ruminants
Authors: Tedeschi L. O. , Galyean M. L. , Hales K. E.
Published: August 2017

Considerable efforts have been made in gathering scientific data and developing feeding systems for ruminant animals in the past 50 years. Future endeavours should target the assessment, interpretation and integration of the accumulated knowledge to develop nutrition models in a holistic and pragmatic manner. We highlight some of the areas that need improvement. A fixed metabolisable-to-digestible energy ratio is an oversimplification and does not represent the diversity of existing feedstock, but, at the same time, we must ensure the internal consistency and dependency of the energy system in models. For grazing animals, although data exist to compute energy expenditure associated with walking in different terrains, nutrition models must incorporate the main factors that initiate and control grazing. New equations have been developed to predict microbial crude protein (MCP) production, but efforts must be made to account for the diversity of the rumen microbiome. There is large and unexplained variation in the efficiency of MCP synthesis (9.81–16.3 g MCP/100 g of fermentable organic matter). Given the uncertainties in the determination of MCP, current estimates of metabolisable protein required for maintenance are biased. The use of empirical equations to predict MCP, which, in turn, is used to estimate metabolisable protein intake, is risky because it establishes a dependency between these estimates and creates a specificity that is not appropriate for mechanistic systems. Despite the existence of data and knowledge about the partitioning of retained energy into fat and protein, the prediction of retained protein remains unsatisfactory, and is even less accurate when reported data on the efficiency of use of amino acids are employed in the predictive equations. The integrative approach to develop empirical mechanistic nutrition models has introduced interconnected submodels, which can destabilise the predictability of the model if changed independently.
Experimental validation of a new approach for rice fertiliser recommendations across smallholder farms in China
Authors: Yang Fuqiang , Xu Xinpeng , Ma Jinchuan , He Ping , Pampolino Mirasol F. , Zhou Wei
Published: August 2017

Inappropriate fertiliser applications have caused a series of environmental problems and threaten the sustainable production of rice in China. The aim of this study was to evaluate the effects of a new approach, Nutrient Expert (NE), a nutrient decision support tool for rice (Oryza sativa L.). Experimental validation was carried out under field conditions from 2013 to 2015 at 211 sites in the main rice-growing regions of China. The results showed that, compared with current farmers’ fertiliser practices (FP) and soil testing (ST), the NE approach balanced nutrient application – decreased the nitrogen (N) and potassium (K) rates, and increased the phosphorus (P) rate – and improved grain yield, nutrient uptake, and fertiliser use efficiency. The NE treatment produced a 3.5–6.3% higher grain yield, 2.3–14.2% higher N, P, and K uptake in aboveground plant dry matter, and higher agronomic efficiency, apparent recovery efficiency (RE), and partial factor productivity of applied N and K, but not for P. In particular, the RE of the NE approach was greater by 12.2 and 8.4 percentage points for N, 3.7 and 2.9 percentage points for P, and 16.3 and 6.4 percentage points for K, compared with FP and ST respectively. The results obtained from field validation suggested that the NE approach could predict target yields; nutrient uptake of N, P, and K within specific ranges; and could be used as a tool to make fertiliser recommendation for rice in China.
Those who help us understand our favourite global TV series in a local language
Authors: Luczaj Kamil , Holy-Luczaj Magdalena
Published: August 2017

The main aim of this article is to critically analyse and systematise the debate concerning non-professional subtitling of TV series and movies in some non-English-speaking countries. Most of the studies on fansubbing deal with a specific problem, and they are based on various theoretical frameworks. This paper attempts to merge them into one coherent framework that can serve as a basis for subsequent research. The article addresses the issue of non-professional translation as a solution to the lack of official translations, but also as an alternative strategy for translating the texts of popular culture.

The paper is divided into four parts. The first defines the phenomenon of fansubbing. The second shows how professional and non-professional translations differ. The following two parts, based on different national case studies, answer the questions: who are fansubbers, and what are their motivations?
What does sport psychology have to offer interpreting?
Authors: Horváth Ildikó
Published: August 2017

Sports psychology has a great deal of potential for interpreting and interpreter training, as stress seems to be one of the major psychological factors influencing an interpreter’s professional behaviour. A competitive sports situation is similar to an interpreting assignment, as both are characterized by the need of the performers, the athlete or the interpreter to achieve. They cannot escape from the situation, and they need to achieve what they have undertaken to do. Their performance on the day depends on external and internal factors that they need to control efficiently. Stress is and has for some time been a widely-researched topic in interpreting studies, as it seems to be a fact of life for interpreters. Stress research in interpreting has, however, focused mainly on the external factors influencing an interpreter’s performance. This paper presents an outline of sports psychology and reviews the literature on the psychology of stress. It then presents research conducted on stress in the context of interpreting. Finally, it examines how we can help our students cope with stress and control the internal factors influencing their performance as interpreters.
Rewriting in English-Chinese translation of brand names
Authors: Ying Cui
Published: August 2017

A brand name is an essential part of an advertising campaign, identifying and being closely associated with a product or a manufacturer. One of the major functions of a brand name is to catch the attention of the audience and enhance their memorization. This research takes English-Chinese translation of brand names as an example and studies a prominent feature or strategy of brand name translation, namely rewriting to establish images in relation to the original pronunciation and/or logo. The translation of brand names is not bound by the original semantic meaning and is highly flexible, but it often retains the original sound or pronunciation. In the case of English-Chinese translation, brand names are often rewritten in that a new meaning is presented in the translation and images are established that are associated with the product or manufacturer. This study views image in its broadest sense, establishes a framework of images covering both concrete and abstract versions and discusses the functions of images in increasing the memorability of a brand name and engaging the audience’s emotions. A corpus of 316 English brand names with Chinese translations is considered and two examples are selected for discussion, one looking at the establishment of a concrete image and the other an abstract image. Such rewriting is analysed in relation to the functions of brand names in the hope of providing translators with a point of reference.