bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing Leaching of Potentially Hazardous Elements from Cookware during Cooking: A Serious Public Health Concern
Authors: Ali Sultan Saif Ali , Ahmed Khan Fawad , Wahab Abdul , Fatima Batool , Khalid Hira , Bahader Ali , Safi Sher Zaman , Selvaraj Chandrabose , Ali Abid , Alomar Suliman Yousef , Imran Muhammad
Published: July 2023

The intake of toxic metals from cooking utensils through food is of growing concern to the medical community. This intake poses serious risk to human health. In many developing countries, different types of contaminated metals scraps are used to make cooking utensils. The leaching of both nutritionally essential and toxic metals in significant quantities from cookware during the cooking process results in food contamination and poses a substantial health risk. In the present study, the leaching of some toxic and potentially toxic metals from cooking utensils into different solutions and food was investigated. A preliminary survey indicated that the majority of individuals tend to use aluminum cookware due to its affordability, overlooking the potential health risks associated with these inexpensive and lower-quality cooking utensils. XRF analysis revealed that aluminum, steel, and copper cookware had K, Ca, Pb, Cd, Ni, V, Sn Mo, Zn, Bi, and Tb as contaminants. In addition, aluminum (3.2 ± 0.25 to 4.64 ± 0.20 g/kg) and copper cookware (2.90 ± 0.12 g/kg) were highly contaminated with lead. The time and pH-dependent study revealed that leaching of metals (Al, Pb, Ni, Cr, Cd, Cu, and Fe, etc.) into food was predominantly from anodized and non-anodized aluminum cookware. More metal leaching was observed from new aluminum cookware compared to old. Acidic food was found to cause more metals to leach during cooking. Blood metal analysis of the local population revealed the presence of high concentrations of Al, Pb, Cd, and Ni. In conclusion, leaching of toxic or potentially toxic metals from cookware into food, especially from anodized and non-anodized aluminum cookware, poses a potential public health risk. Practical applications: Cooking utensils are routinely used for the preparation of food. However, the harmful impact posed by these essential items is largely unknown. The current research briefly explains the toxic metals leaching from cookware in a pH-dependent manner and leaves a message to the public, especially in developing countries like Pakistan, regarding the type of cookware suitable for cooking purposes.
Improvement in Infection Prevention and Control Compliance at the Three Tertiary Hospitals of Sierra Leone following an Operational Research Study
Authors: Kamara Rugiatu Z. , Kamara Ibrahim Franklyn , Moses Francis , Kanu Joseph Sam , Kallon Christiana , Kabba Mustapha , Moffett Daphne B. , Fofanah Bobson Derrick , Margao Senesie , Kamara Matilda N. , Moiwo Matilda Mattu , Kpagoi Satta S. T. K. , Tweya Hannock M. , Kumar Ajay M. V. , Terry Robert F.
Published: July 2023

Implementing infection prevention and control (IPC) programmes in line with the World Health Organization’s (WHO) eight core components has been challenging in Sierra Leone. In 2021, a baseline study found that IPC compliance in three tertiary hospitals was sub-optimal. We aimed to measure the change in IPC compliance and describe recommended actions at these hospitals in 2023. This was a ‘before and after’ observational study using two routine cross-sectional assessments of IPC compliance using the WHO IPC Assessment Framework tool. IPC compliance was graded as inadequate (0–200), basic (201–400), intermediate (401–600), and advanced (601–800). The overall compliance scores for each hospital showed an improvement from ‘Basic’ in 2021 to ‘Intermediate’ in 2023, with a percentage increase in scores of 16.9%, 18.7%, and 26.9% in these hospitals. There was improved compliance in all core components, with the majority in the ‘Intermediate’ level for each hospital IPC programme. Recommended actions including the training of healthcare workers and revision of IPC guidelines were undertaken, but a dedicated IPC budget and healthcare-associated infection surveillance remained as gaps in 2023. Operational research is valuable in monitoring and improving IPC programme implementation. To reach the ‘Advanced’ level, these hospitals should establish a dedicated IPC budget and develop long-term implementation plans.
Gamma-ray Emission and Variability Processes in High-Energy-Peaked BL Lacertae Objects
Authors: Kapanadze Bidzina
Published: July 2023

BL Lac objects are active galactic nuclei notable for a beamed nonthermal radiation, which is generated in one of the relativistic jets forming a small angle to the observer’s line-of-sight. The broadband spectra of BL Lacs show a two-component spectral energy distribution (SED). High-energy-peaked BL Lacs (HBLs) exhibit their lower-energy (synchrotron) peaks at UV to X-ray frequencies. The origin of the higher-energy SED component, representing the γ-ray range in HBLs, is still controversial and different emission scenarios (one- and multi-zone synchrotron self-Compton, hadronic etc.) are proposed. In γ-rays, HBLs show a complex flaring behavior with rapid and large-amplitude TeV-band variations on timescales down to a few minutes. This review presents a detailed characterization of the hypothetical emission mechanisms which could contribute to the γ-ray emission, their application to the nearby TeV-detected HBLs, successes in the broadband SED modeling and difficulties in the interpretation of the observational data. I also overview the unstable processes to be responsible for the observed γ-ray variability and particle energization up to millions of Lorentz factors (relativistic shocks, magnetic reconnection, turbulence and jet-star interaction). Finally, the future prospects for solving the persisting problems by means of the dedicated gamma-ray observations and sophisticated simulations are also addressed.
Genetic Variability and Molecular Evolution of Tomato Mosaic Virus Populations in Three Northern China Provinces
Authors: Lyu Jinfu , Yang Yuanyuan , Sun Xiaohui , Jiang Shanshan , Hong Hao , Zhu Xiaoping , Liu Yongguang
Published: July 2023

RNA viruses tend to mutate during transmission and host infection, which is critical to viral adaptation and evolution. Tomato mosaic virus (ToMV) is a member of the genus Tobamovirus (family Virgaviridae) and an economically important virus with detrimental effects on tomatoes worldwide. Although the ToMV gene sequences have been completed in China, their genetic diversity and population structure remain unclear. We collected 425 tomato samples from tomato-growing areas in three northern Chinese provinces 2016. Reverse transcription PCR results showed that the average incidence of the virus in the field samples was 67.15%, and ToMV was detected in all test areas. The analysis of ToMV single nucleotide polymorphisms in China showed that ToMV was evolutionarily conserved, and the variation in the whole genome was uneven. Pairwise identity analysis showed significant variability in genome sequences among ToMV strains with genomic nucleotide identities of 73.2–99.6%. The ToMV population in the northern Chinese provinces had purification and selection functions, which were beneficial in the evolution of the ToMV population. Although there has been some distribution of ToMV strains in China, the virus was generally stabilized as a uniform strain under the pressure of purification selection. Our findings show how to monitor the prevalent strains of ToMV and their virulence in China and provide useful information for its prevention and control.
Evaluation of Haematological and Immunological Parameters of the ASFV Lv17/WB/Rie1 Strain and Its Derived Mutant Lv17/WB/Rie1/d110-11L against ASFV Challenge Infection in Domestic Pigs
Authors: Franzoni Giulia , Petrini Stefano , Mészáros István , Dei Giudici Silvia , Righi Cecilia , Olasz Ferenc , Zinellu Susanna , Tamás Vivien , Pela Michela , Gallardo Carmina , Zádori Zoltán , Oggiano Annalisa , Feliziani Francesco
Published: July 2023

African swine fever virus (ASFV) is the etiological agent of a haemorrhagic disease that threatens the global pig industry. There is an urgency to develop a safe and efficient vaccine, but the knowledge of the immune–pathogenetic mechanisms behind ASFV infection is still very limited. In this paper, we evaluated the haematological and immunological parameters of domestic pigs vaccinated with the ASFV Lv17/WB/Rie1 strain or its derived mutant Lv17/WB/Rie1/d110-11L and then challenged with virulent Armenia/07 ASFV. Circulating levels of C-reactive protein (CRP), 13 key cytokines and 11 haematological parameters were evaluated throughout the study. Lv17/WB/Rie1 triggered an inflammatory response, with increased levels of CRP and pro-inflammatory cytokines, and induced lymphopenia, thrombocytopenia and a decline in red blood cell (RBC) parameters, although this was transitory. Lv17/WB/Rie1/d110-11L triggered only transitory thrombocytopenia and a mild inflammatory reaction, with no increase in serum levels of pro-inflammatory cytokines, but it raised IL-1Ra levels. Both strains counteracted several adverse reactions elicited by virulent challenge, like thrombocytopenia, a decline in RBC parameters, and inflammation. Within this paper, we provided a deep portrayal of the impact of diverse ASFV strains on the domestic pig’s immune system. A better understanding of these immune–pathological mechanisms would help to design suitable vaccines against this disease.
Comprehensive Analysis of the Failure Potential of a Motorway Landslide in Dabu County, China
Authors: Chen Sheng , Hao Yang , Zhang Wencai , Sun Ying , Liu Xue
Published: July 2023

Because the failure potential of a landslide is difficult to assess, a motorway landslide that has obviously deformed was used as a case study in this research. Several multi-integrated geotechniques, including field investigation, drilling, electrical resistivity tomography (ERT), stability analysis, and numerical simulations, were used to achieve this goal. Field investigation with drilling was used to roughly determine the failure potential mass boundary and the material composition ERT technique was further used to distinguish the structure and composition of underground materials; the results agreed well with the field investigation, as well as the drilling data in the lithology judgement. The above investigations also showed the failure potential mass is in a slow sliding state and the slip surface roughly follows the contact zone between the upper soil and bedrock. Next, stability analysis based on the limit equilibrium method (LEM) was used to judge the current stability status of the slope, and its factor of safety (FOS) was 1.2 under the natural condition, 1.05 under the earthquake condition, and 1.15 under the rainfall condition. Based on the assessed potential slip surface and digital elevation data, a three-dimensional smoothed particle hydrodynamics (SPH) model was used to simulate the failure potential process. The dynamic information of the run-out behavior, including velocity, movement distance, and frictional energy, can be obtained, which is useful for hazard prediction.
Axial Groundwater Contaminant Dispersion Modeling for a Finite Heterogeneous Porous Medium
Authors: Radha Rashmi , Singh Mritunjay Kumar
Published: July 2023

In this study, a two-dimensional contaminant transport model with time-varying axial input sources subject to non-linear sorption, decay, and production is numerically solved to find the concentration distribution profile in a heterogeneous, finite soil medium. The axial input sources are assigned on the coordinate axes of the soil medium, with background sources varying sinusoidally with space. The groundwater velocities are considered space-dependent in the longitudinal and transversal directions. Various forms of axial input sources are considered to study their transport patterns in the medium. The alternating direction implicit (ADI) and Crank-Nicolson (CN) methods are applied to approximate the two-dimensional governing equation, and the obtained algebraic system of equations in each case is further solved by MATLAB scripts. Both approximate solutions are illustrated graphically for various hydrological input data. The influence of various hydrogeological input parameters, such as the medium’s porosity, density, sorption conditions, dispersion coefficients, etc., on the contaminant distribution is analyzed. Further, the influence of constant and varying velocity parameters on groundwater contaminant transport is studied. The stability of the proposed model is tested using the Peclet and Courant numbers. Substantial similarity is observed when the approximate solution obtained using the CN method is compared with the finite element method in a special case. The proposed approximate solution is compared with the existing numerical solutions, and an overall agreement of 98–99% is observed between them. Finally, the stability analysis reveals that the model is stable and robust.
Features of digitalization in accounting: current state and development trends
Authors:   Federal State Autonomous Educational Institution of Higher Education “Lobachevsky State University of Nizhny Novgorod”, Nizhny Novgorod, Russia, Druzhilovskaya T.Y.
Published: July 2023

One of the most important trends in the development of accounting (including in healthcare organizations) is the increased use of digital technologies in it. The article examines the features of the use of various digital technologies in modern accounting. The digitalization of accounting is of great interest to scientists. However, different scientific works use different conceptual apparatus in relation to these issues. The author of the article presents an interpretation of the correlation of different terms in the field of questions of the use of digital technologies in accounting. The question of the possibility of replacing the accounting profession with artificial intelligence has also been studied. Based on the analysis of the characteristics of the requirements for the accounting profession, the conclusion is substantiated that artificial intelligence will be a great assistant to the accountant, but will not supplant the accountant profession.
Features of accounting for advertising expenses in the tax accounting of medical organizations
Authors:   Department of Economics and Management of the Institute of Economics, Management and Law, Moscow City University. Moscow, Shinkareva O.V. , Agafonov D.S. ,   Moscow City University of Management of the Government of Moscow named after Yu.M. Luzhkov. Moscow
Published: July 2023

The article is devoted to the analysis of the peculiarities of accounting for advertising expenses in the tax accounting of medical organizations. The criteria for classifying expenses as advertising are shown, it was noted that part of advertising expenses is rationed — their size should not exceed 1% of sales revenue. We have discussed in detail the types of advertising expenses that are not normalized. Practical situations are given that describe specific examples of classifying expenses as advertising, normalized or non-normalized. We analyzed cases that determine the amount of normalized expenses that can be taken into account for profit tax purposes, it was noted that the organization needs to monitor whether the costs of normalized advertising exceed the limit for the tax period and, in order to optimize taxation, plan the time and costs of normalized advertising in such a way that it is possible to take into account the maximum possible amount of advertising costs in the expenses.
Digital environment of a medical institution: implementation and provision
Authors:   Federal State Budgetary Educational Institution of Higher Education “Russian Economic University named after G. Plekhanov”, Ministry of Science and Education of the Russian Federation, Moscow, Russia, Lebedev V.A. , Lebedeva E.I. ,   Non-profit Partnership “Institute of Professional Accountants and Auditors of Russia”, Moscow, Russia, Urintsov A.I. ,   Federal State Budgetary Educational Institution of Higher Education “Russian Economic University named after G. Plekhanov”, Ministry of Science and Education of the Russian Federation, Moscow, Russia
Published: July 2023

At present, the implementation by the state of its social function in the field of healthcare is of particular importance. The digital environment makes it possible to provide medical services in remote areas. The modern directions of the organization of the digital environment in medical institutions are considered; the impact of OT technologies on the level and quality of medical care, including the role and limits of the use of telemedicine technologies. The analysis of the organization of the provision of medical services by branches of a medical institution is carried out; features of the legal status of remote workers and the corresponding tax obligations of the employer.
STRUCTURE OF AGGLOMERATIONS AS ONTOLOGICAL BASIS OF TERRITORIAL PLANNING
Authors:   Voronezh State Technical University, MOROZOVA L.V. , ENIN A.E. ,   Voronezh State Technical University
Published: July 2023

The spatial organization and regulation of human activity through territorial planning is a very urgent problem for many countries of the world. The issue of the optimal network of population resettlement has always been acute for Russia for a number of reasons, some of which were taken into account in the course of the administrative-territorial reform. In this aspect, the determination of the structural and dynamic characteristics of the settlement network is becoming increasingly important. The article deals with methodological issues of studying the regional spatial structure of the agglomeration. Modeling builds a number of levels with the spatial distribution of the population by function, by the potential and ability of the territory to implement the considered settlement options. This hierarchy represents the different sides of the interaction in accordance with the selected parameter. The constructed layers are a convenient tool for determining the initial agglomerations and promising growth points of the region, the development of which will stimulate the optimal use of the territorial potential, as well as increase the economic and investment potential. The described approach to the study of the spatial structure of the agglomeration can be in demand for sound territorial and urban planning and management, for an effective policy of regional development, etc.
STUDY FOR THE IMPACT OF RENEWABLE ENERGY SOURCES ON THE ENVIRONMENTAL POTENTIAL OF THE TERRITORY OF THE RUSSIAN FEDERAL SUBJECT
Authors:   Don State Technical University, SHEINA S.G. , FEDOROVSKAYA A.A. ,   Don State Technical University
Published: July 2023

The article discusses the process and significance of a multi-criteria assessment of the territory to ensure its sustainable development, as well as the choice of renewable energy sources (hereinafter referred to as RES) and their location in terms of preserving the ecological potential of the landscape of the territory of the subject of the Russian Federation. The key feature is the determination of the impact of RES on the ecological potential of the territory due to the multicomponent components for evaluation. It is known that one of the advantages of renewable energy is to reduce the negative impact on the environment, however, different types of renewable energy have different effects on the natural system of the territory, both direct and indirect. A comprehensive assessment of the territory of a constituent entity of the Russian Federation is proposed as a tool that allows integrating various types of information on the state of the potential of the territory for the use of renewable energy sources, the ecological landscape, anthropogenic load and other data into a single system for a qualitative spatial analysis of the regional system.
BUILDING STRUCTURAL SYSTEM MADE OF INDUSTRIAL FRAME-PANEL ELEMENTS
Authors:   Moscow State University of Civil Engineering, FEDOROVA N.V. ,   Scientific Research Institute of Construction Physics of the Russian Academy of Architecture and Construction Sciences, SAVIN S.YU. ,   Moscow State University of Civil Engineering; Scientific Research Institute of Construction Physics of the Russian Academy of Architecture and Construction Sciences, KOLCHUNOV V.I. ,   Moscow State University of Civil Engineering; Scientific Research Institute of Construction Physics of the Russian Academy of Architecture and Construction Sciences, MOSKOVTSEVA V.S. ,   Scientific Research Institute of Construction Physics of the Russian Academy of Architecture and Construction Sciences, AMELINA M.A. ,   South-West State University
Published: July 2023

The paper presents a new structural solution of the precast-monolithic frame for prefabricated residential and civil buildings of various storeys manufactured from prefabricated industrial reinforced concrete elements. The precast frame structures include L-shaped and inverted U-shaped precast elements, installed in the longitudinal and transverse directions and forming a frame, hollow-core slabs and bracing perforated beams of the outer contour, on which fencing non-bearing wall structures are supported within each storey. The computational model of the precast-monolithic building frame was developed using different degrees of discretization at different stages of the analysis. This allowed to obtain both a general picture of structural system deformation in the limiting and over limit states caused by special and emergency actions, and a detailed picture of the stressed state in concrete and reinforcement of structural elements before and after cracking. The paper provides the results of the comparative analysis of the effectiveness of application of the proposed structural system in the mass construction as compared with the applied constructions of large-panel buildings. It has been shown that the application of the proposed structures of panel-frame elements allows considerably reduce the material capacity, cost and transportation expenses of the reinforced concrete frame by up to 30 %, ensuring the mechanical safety of the building.
Modelagem geoestatística do volume comercial e sortimentos em povoamentos de Pinus taeda L.
Authors: Grazeke de Oliveira Rafael , Libanio Pelissari Allan , Costa Cysneiros Vinicius , Eduardo Arce Julio
Published: July 2023

Para aumentar a precisão dos resultados dos inventários florestais, se faz necessário o uso de ferramentas além das tradicionais. Com isso, o presente trabalho objetivou a modelagem espacial do volume comercial e dos sortimentos de Pinus taeda L. com geoestatística. Essa técnica parte do pressuposto que as unidades amostrais mais próximas no espaço geográfico são mais semelhantes. A área de estudo é um projeto silvicultural da espécie Pinus taeda com 145,3 ha, implantado no ano de 2002, com espaçamento de 3 m x 2,5 m. Neste projeto, foi realizado um primeiro desbaste misto aos 9 anos, no qual a densidade de indivíduos foi reduzida em 50% e um segundo desbaste seletivo aos 14 anos, retirando 50% dos indivíduos remanescentes. Os dados foram coletados em 2020, sendo mensuradas 30 unidades amostrais circulares com área de 600 m² cada. Para modelagem da altura em diferentes diâmetros e dos sortimentos, foram cubadas 30 árvores selecionadas no povoamento. Foram testados seis modelos de relação altura-diâmetro, sendo os de Stoffels, Trorey, Curtis, Campos e Leite, Azevedo e Henriksen. Para a estimativa dos sortimentos, foi utilizado o Polinômio de 5° Grau. As semivariâncias foram calculadas, com objetivo de verificar a dependência espacial das variáveis analisadas. Os resultados demostraram que foi possível modelar e espacializar o volume comercial e os sortimentos de P. taeda por meio da geoestatística. O mapeamento espacial dos sortimentos permite aprimorar o planejamento das atividades de colheita, fornecendo maior exatidão às estimativas por meio da localização geográfica das classes de volume.
Mimosa caesalpiniifolia Benth. as an alternative for wood production in Northeast Brazil
Authors: Mauricio Medeiros Reis Paulo , Lorensi do Canto Juliana , Gilberto Meza Ucella Filho João , De Melo Almeida Débora , Rafaella Ferreira da Silva Bruna , Nascimento de Sousa Alex , Guenther Costa da Silva Gualter
Published: July 2023

Mimosa caesalpiniifolia is a native species from Northeast Brazil, with good soil and climate adaptation, fast growth and potential for multiple use. Because of these characteristics, it has been considered a promising species for forestry. This work aimed to evaluate the growth and productivity of Mimosa caesalpiniifolia at 75 months of age, in a homogeneous plantation located in the state of Rio Grande do Norte, Northeastern Brazil. The data were collected in a 0.05 ha plot with 84 individuals, submitted to thinning at 12 and 55 months. The variables height (H), diameter at breast height (DBH), and diameter at base (DAB) were evaluated. The productivity of the plantation was estimated in terms of total volume (m3) and stacked volume (st), number of stems and mean annual increment (MAI). On average, the individuals were 4.85 m tall, 12.05 cm in diameter at the base (DAB) and 8.42 cm DBH. Each individual presented an average of 6.07 stems. The estimated productivity was 43.88 m³ ha-1, with MAI of 7.02 m³ ha-1 year-1, and the estimated stacked wood volume was 111.89 st ha-1. The results showed the high potential of the species for the production of stakes and fence posts, as well as for the production of kindling and firewood, aiming at the use of all the biomass produced. Therefore, the planting of this species for the production of wood serves as an alternative to meet demands in the Northeast of Brazil.
Análise da vegetação em área de mata ciliar no Baixo São Francisco, em Sergipe
Authors: Maria Guimarães Marroquim Paula , Anastácio Ferreira Robério , Correia Gama Dráuzio , Maria Moreira Duarte Juliana , Santos de Almeida Ednei
Published: July 2023

A pressão pelo uso do solo, principalmente para expansão agropecuária e ocupação urbana, têm sido os principais obstáculos à preservação das matas ciliares. Este trabalho foi realizado com o objetivo de analisar a composição florística e a estrutura fitossociológica do estrato arbustivo-arbóreo de um fragmento de mata ciliar na região do Baixo Rio São Francisco, no estado de Sergipe. O fragmento foi analisado pelo método de amostragem sistemática, utilizando-se 25 parcelas de 400m² (20m x 20m). Todos os indivíduos com circunferência à altura do peito (CAP) igual ou superior a 6cm foram registrados, tendo seus diâmetros mensurados e alturas estimadas. As amostras de material botânico foram levadas aos herbários da Universidade Federal de Sergipe (ASE) e do Instituto de Meio Ambiente de Alagoas (MAC), onde foram identificadas e depositadas em suas coleções. As famílias com maior número de espécies foram Fabaceae, Myrtaceae, Rubiaceae e Euphorbiaceae. A espécie com o maior índice de valor de importância (IVI), foi Croton jacobinensis Baill. destacando-se também em termos de dominância, freqüência e densidade. No estrato vertical médio observou-se 75,6% do total de indivíduos. O remanescente apresentou uma diversidade consideravelmente acima do esperado para ambientes ciliares em área domínio de Caatinga, tendo a condição edáfica diretamente associada a esse aspecto florístico e estrutural, principalmente para a vegetação encontrada na região de fundo de vale.
Características hidrogeomorfométricas e da cobertura do solo da microbacia Rio Caranguejo, Amazônia Ocidental, Brasil
Authors: Alves dos Santos Janderson , Candido Franco Rosell Eduardo , Maia Emanuel , Ânderson Fulan João , Batista Belarmino Rodrigues João , Costa Guaraná Araujo Emmanoella , Vendruscolo Jhony
Published: July 2023

É essencial planejar a gestão dos recursos naturais para o desenvolvimento sustentável na região amazônica tendo como base as informações das características da paisagem. Diante do exposto, o presente trabalho teve como objetivo disponibilizar informações topográficas, geométricas e hidrográficas, e da cobertura do solo da microbacia Rio Caranguejo. Estas informações foram obtidas por meio de equações e sensoriamento remoto, utilizando os softwares QGIS 2.10.1, TrackMaker e Google Earth, imagens altimétricas registradas pelo satélite ALOS (sensor Palsar). A microbacia tem área de 7,85 km2, perímetro de 19,26 km, forma alongada, baixa suscetibilidade a enchentes, altitudes de 207 a 254 m, predominância de relevo suave ondulado (67,39%), 68,03% da área apta a extremamente apta a mecanização agrícola e com baixa influência na propagação de incêndios, rede de drenagem com padrão dendrítico, 3ª ordem de drenagem, baixa densidade de nascentes, média densidade de drenagem, coeficiente de manutenção de 1.062,2 m2 m-1, baixo tempo de concentração. A microbacia do rio Caranguejo tem 82,29% de sua área total ocupada pelo sistema agropecuário, no entanto, recomenda-se práticas de manejo conservacionistas do solo e da água, para reduzir o impacto destes sistemas nos recursos naturais da mesma. Também são recomendados estudos sobre a distribuição espacial da vegetação nativa por estabelecimento agropecuário privado, para se avaliar a situação das reservas legais.
Alternativas actuales en el manejo del glaucoma de ángulo abierto en México; posición de expertos
Authors: Dávila-Macías Jorge Omar , Dixon-Rosas Sandra , Hernández-Bautista Wendy , Ortega-Santana José Francisco , Ponce José Ramón , de la Torre-Tovar Juan Daniel , Vizzuett-Mendoza Ericka Gabriela
Published: July 2023

Glaucoma is the first cause of irreversible blindness worldwide. It is estimated up to 1.94 million inhabitants with glaucoma in our country. The glaucoma management faces several and severe issues, besides the fact that up to 80% of the patients worldwide does not comply with the pharmacological treatment. Based on that situation, a panel of experts analyzed the current glaucoma state of the art in Mexico and the advantages, limitations, and treatment alternatives. The academic coordinator distributed a Delphi questionnaire to the group. The studies of the patients that include the diverse indicated therapeutic options were mapped. The group analyzed the barriers and opportunities for implementing new treatments for glaucoma. They provided recommendations for improving the treatment and mitigate unmet needs. It is recommended to enhance the continuing medical education efforts on glaucoma in the general Ophthalmology services and promote early referral to the glaucoma experts to provide timely interventions, save resources, and improve both the treatment outcomes and the patients’ quality of life.
Los nombres comunes de los principios activos llevan artículo en español
Authors: Villegas Fontela Álvaro , Gallego Borghini Lorenzo
Published: July 2023

Non-proprietary drug names are common nouns. As such, they require the use of a definite article in Spanish. However, there is a trend to omit the article before drug names in scientific texts written in Spanish, as well as in translations, such as the summaries of product characteristics published by EMA (European Medicines Agency). Dropping the article in these cases is against Spanish grammar correctness. The correct usage can be found in the Spanish Ortografía from Real Academia Española and in several style guides. It is also recorded extensively in reference textbooks; thus, it is the usage that should be promoted in the medical and pharmaceutical sector.
Comparison between enzyme-multiplied immunoassay technique (EMIT) and high-performance liquid chromatography with ultraviolet detection (HPLC-UV) for the therapeutic drug monitoring of mycophenolic acid in Mexican pediatric patients with renal transplantation
Authors: Reyes-Pérez Herlinda , Quiroz-Moguel Alan Ricardo , Velásquez-Jones Luis , Hernández Ana María , García-Roca Pilar , Medina-Aymerich Lorena , Medeiros-Domingo Mara , Castañeda-Hernández Gilberto , González-Ramírez Rodrigo
Published: July 2023

Introduction. Mycophenolic acid (MPA) is an immunosuppressant; thus, monitoring of plasma levels is recommended. The most popular analytic methods used for the MPA quantification are the enzyme-multiplied immunoassay technique (EMIT) and the high-performance liquid chromatography with ultraviolet detection (HPLC-UV). The purpose of the present study was to compare both methods performances for the therapeutic drug monitoring of MPA in Mexican pediatric patients with renal transplantation. Material and Methods. A prospective cross‐sectional study was carried out, 25 patients with kidney transplantation were included. Mycophenolate mofetil was administered and blood samples were drawn at 0, 0.5, 1, 2, 3, 4, 6, 8, and 12 h after medication. Plasma samples were obtained and divided into two aliquots for further quantification by both methodologies. Each concentration determined by EMIT was compared with the corresponding quantification by HLPC-UV. Bias and precision were estimated as previously described by Sheiner and Beal. Results. EMIT overestimated MPA concentrations with a positive bias of 59.25% and a precision of 54.85%. AUC0-12, the recommended parameter for therapeutic drug monitoring of MPA, was significantly overestimated by EMIT in more than 50%. Discussion. Overestimation derives from metabolite cross-reactivity in EMIT, which does not occur with HPLC-UV. Hence, HPLC-UV appears to be a more suitable method for MPA therapeutic drug monitoring in Mexican pediatric patients with renal transplantation.
A Review of Financial Literacy in Southeast Asian Cognate Countries
Authors: Sinaga Endang Komesty , Waspada Ikaputra
Published: July 2023

A cashless society is a collective vision of world citizens to create a payment system that is faster, more flexible, and more automatic. This study aims to formulate findings on publications conducted in 2012-2022, focusing on a cashless society. Using the Systematic Literature Review approach, this study uses 14 main sources from the Scopus database to identify shared understanding, supporting factors, and the impact of a cashless society from the perspective of researchers. This study found that the formation of a cashless society is a solution for efforts to grow the economy and speed up societal transactions. Another benefit is the prevention of criminal acts of corruption, extortion, and fraud, where electronic payments made in a registered manner have suppressed these crimes. The dark side of a cashless society is the potential for privacy violations and paralysis of the economic system caused by internet system failures
A Comprehensive study on Review of literatures on Tuberculosis
Authors: Kanta B Laxmi , Subburaman C
Published: July 2023

Background of the study: Tuberculosis is a contagious illness caused by bacteria (Mycobacterium tuberculosis) that mostly affects the lungs. When an infected individual coughs or sneezes, it can spread via the air. Tuberculosis imposes an economic cost not only on the afflicted person, but also on his whole family and entire nations due to lost output during the ill period. Every year, ten million individuals have tuberculosis, resulting in a significant loss in the nation's per capita revenue.  Objectives of the study: A greater number of articles by diverse writers demonstrate their interest in researching one economic stage of TB. Few authors have conducted reviews of the literature on the economic morbidity of TB in recent decades; however, given the economic elements in recent times, a more complete assessment is performed here to identify the Research Gap. Findings: The researcher reviewed the literature on economic morbidity of tuberculosis in this paper in order to assist other researchers, academicians, policymakers, and practitioners in taking a closer look at the recent trends and growths, statistical methods, financial gaps, and achievement rates in this studies. Conclusion: The author has examined various papers and proposed a comprehensive summary of various studies conducted in India and abroad, identifying certain recommendations and research gaps, as well as methods that would provide hints for future research in the area of Health Economics under the headings of tuberculosis.
Activity-Based Positioning and Playing Technique Instruction and Implementation in Amature Guitar Education
Authors: Ceviz Berk
Published: July 2023

The aim of this study is to prepare activity-based lesson plans for amateur guitar education to teach basic positioning and playing techniques, and to test the effectiveness of this teaching method. The research model is a single-group pretest-posttest design, and it was carried out with 5 students at the beginner level for 4 lessons of instructional process. The data obtained from performance tests were evaluated based on a 5-point Likert scale determined by three field experts, and the average success scores of the students for the relevant unit were determined. As a result of the evaluation, student achievements ranged between 87.19-100, and it was concluded that guitar education based on activity-based lesson plans was successful.
Effect of Seasons on Fatty Acid Composition of Laurencia obtusa (Hudson) J.V. Lamouroux, 1813 From Sinop Coast of the Black Sea
Authors: ERSOY KARAÇUHA Melek , YILDIZ Gökhan , KARAÇUHA Ali
Published: July 2023

The aim of this study was to determine the fatty acid profile of Laurencia obtusa collected from the Sinop coast. The fatty acids profile were analyzed by GC/MS and their seasonal variation was studied. Along the sampling, it was identified 36 different fatty acids in L. obtusa. During the research, it was determined that the most abundant fatty acid was palmitic acid with values ranging from 33.78±1.03% in winter to 44.51±1.70% in summer. At the end of the study, it was determined that the season in which L. obtusa was richest in terms of PUFA and SFA contents was spring and in terms of MUFA content was autumn. In addition, in the study, It has been determined that the PUFA/SFA ratio in L. obtusa varied between 0.10% and 0.23% from winter to summer, and the total n-6/n-3 PUFA ratio changed between 1.14% and 2.37% from summer to autumn. It was determined that the atherogenicity index (AI) value changed between 1.75 and 1.97 from autumn to summer, and the thrombogenicity index (TI) value changed between 1.58 and 2.22 from winter to autumn. As a result of the research, it was revealed that the seasons have a significant effect on the fatty acid profile.
El Docente y el diseño universal de aprendizaje para la creación de entornos de aprendizaje inclusivo
Authors: Colcha-Meléndrez Carmen , Esteves-Fajardo Zila Isabel
Published: July 2023

La concepción moderna de la Educación debe girar su mirada hacia los postulados de Educación Para Todos y Educación Inclusiva. Dicha postura supera la visión reduccionista de equiparar diversidad con discapacidad, puesto que todos los educandos tienen una variedad de necesidades de aprendizaje que el docente moderno deber conocer y atender. Considerando lo planteado se presenta este articulo enmarcado en examinar los aportes del Diseño Universal de Aprendizaje (DUA) como un elemento clave para lograr la creación de entornos de aprendizaje verdaderamente inclusivos. El mismo responde a una investigación a nivel descriptiva y de tipo documental bibliográfico. Finalmente, se enuncia que la creación de entornos de aprendizaje verdaderamente inclusivos basados en el DUA, debe darse la apropiación de contextos y escenarios a fin de accionar educativamente asumiendo la inclusión como un principio soportado desde el reconocimiento del otro en la diversidad y desde ahí desplegar innovaciones y mejoras educativas.
Sobreprotección de los padres en el desarrollo emocional en niños con necesidades educativas especiales
Authors: Morocho-Alvarado Madale Beatriz , Cuadrado-Vaca Jorge Gustavo
Published: July 2023

El objetivo general de la investigación fue describir la sobreprotección de los padres en el desarrollo emocional en niños con necesidades educativas especiales. Se planteó desde el paradigma positivista con un enfoque cuantitativo, apoyado en un diseño documental-bibliográfico, a través de la exploración, recolección y análisis crítico, mediante la búsqueda, la reflexión y estudio, de fuentes documentales tales como artículos arbitrados, tesis, entre otros, y construyendo métodos relacionados al discernimiento del fenómeno y así evaluar o considerar nuevos contextos. Se consideró un diseño no experimental, debido que no existe manipulación de las fuentes. Se concluye que, la sobreprotección en niños con necesidades educativas especiales, debe están orientada de una forma positiva a mejorar el desarrollo emocional de los niños, generando la independencia del escolar, contribuyendo al acompañamiento en conjunto con los docentes, canalizando las emociones de los infantes, lograr la interrelaciones entre los diferentes grupos, mejorar el desenvolvimiento.
Habilidades gerenciales y desempeño laboral de los funcionarios públicos, Cañar, Ecuador
Authors: López-Montero Tannya Alexandra , Castillo-Castillo Deisy Carolina
Published: July 2023

El objetivo del estudio fue determinar la existencia de una relación causal entre las habilidades gerenciales y el desempeño laboral de los funcionarios del GADIC. En cuanto a la metodología la investigación tiene un enfoque cuantitativo, ya que se requiere una serie de procesos estadísticos que permitirán representar las características de las dos variables de estudio y el nivel de investigación fue correlacional. Se utilizó método de correlación de Spearman entre las dos variables para calcular la correlación de estas, que son las habilidades gerenciales y el desempeño laboral. En los resultados obtenidos se puede identificar que los funcionarios poseen las competencias y conocimientos necesarios para brindar un buen servicio. Como conclusión, se llegó que los funcionarios poseen un alto porcentaje de habilidades gerenciales y desempeño laboral, ya que la cordialidad, la comunicación, los valores y el respeto son primordiales dentro de las habilidades interpersonales.
Enfermería y manejo de sedación en cuidados intensivos
Authors: González-Gavilánez Gilberth Dagoberto , Solórzano-Intriago Maria Mercedes , Andrade-Pizarro Lisbeth Madelayne , Cevallos-Bravo María Prisila
Published: July 2023

El objetivo general de la presente investigación fue describir la enfermería y manejo de sedación en cuidados intensivos. El trabajo se planteó a partir del enfoque cuantitativo la cual produjo datos descriptivos, que se originaron por la recolección de antecedentes, mediante la indagación, obtención y análisis crítico documental y referencial bibliográfico, basándose en la revisión metódica, rigurosa y profunda de diversas fuentes documentales tales como investigaciones científicas, trabajos arbitrados y tesis. Desde esta exploración y reflexión detallada, se obtuvieron los recaudos necesarios para el desarrollo teórico y las conclusiones respectivas. Se concluye que, propiciar el cuidado a los pacientes en las Unidades de Cuidados Intensivos en los centros hospitalarios, requiere de un equipo multidisciplinario y en especial de enfermería, quienes deben tener el conocimiento y técnicas en el manejo de sedación, brindando la atención de calidad a los pacientes que presentan un estado crítico y sus familiares.
Correlación sexo, patrón esqueletal en la inclinación incisal y la influencia en tejidos blandos
Authors: Cedeño-García Neris Leonardo , Lima-Illescas Miriam Verónica
Published: July 2023

El objetivo del estudio fue correlacionar el patrón esqueletal en la inclinación incisal y la influencia en los tejidos blandos. Se utilizaron 276 radiografías cefálicas laterales enfocándose en el ángulo interincisal, el ángulo nasolabial y correlacionandolo con el sexo y el patrón esqueletal. Existió una diferencia significativa del ángulo nasolabial para el sexo, es decir que la comparación por pares mostró que fue mayor ángulo nasolabial para las mujeres en relación con los hombres. Por otra parte, el ángulo interincisivo indicó una diferencia significativa con el patrón esqueletal, en la Clase I la media fue 126, 94º ±10,21 º, mientras que en la Clase II la media fue 124,88 ±9,7˚ y en la Clase III la media fue 132,31 ±10,33˚. La interacción del sexo y el patrón esqueletal no fue significativa para el ángulo interincisal y el nasolabial.
Factores éticos que influyen en la toma de decisiones gerenciales en el sector cooperativo
Authors: Mainato-Pomavilla Juan Belén , Orbe-Guaraca Mariory Prisila
Published: July 2023

El objetivo del estudio fue analizar los factores éticos que influyen en la toma de decisiones gerenciales en el sector cooperativo de la Ciudad de Cañar, La presente investigación tiene un enfoque cuantitativo para la recolección y análisis de los datos a través del uso de herramientas estadísticas. Los resultados arrojados en la presente investigación indicaron que en las diez (10) cooperativas estudiadas se toman en cuenta los valores éticos para la toma de decisiones gerenciales, ya que hay evidencia de preparación técnica y profesional de los líderes de la cooperativa; por su parte, los líderes promueven y ejercen un liderazgo participativo y democrático. En base a lo analizado se concluye que los valores éticos influyen en las tomas de decisiones gerenciales, ya que los valores como responsabilidad, honestidad, lealtad, respeto, igualdad, honradez, entre otros, son los que impulsan una buena decisión y logran el éxito de las organizaciones.
Impacto de las estrategias motivacionales de la cooperativa Yuyay Ltda. Ecuador
Authors: Pichasaca-Solano Flavio Benjamin , Ordoñez-Espinoza Cristina Guadalupe
Published: July 2023

El objetivo de este estudio estuvo enfocado en determinar el impacto que ha tenido las estrategias motivacionales que la Cooperativa de Ahorro y Crédito Yuyay Ltda, basados en un diagnóstico previo realizado por la institución. La metodología aplicada en la presente investigación fue de tipo cuantitativo, con un enfoque descriptivo de corte transversal y de campo. Los resultados reflejaron que la mayoría de los trabajadores perciben el ambiente de trabajo como confortable la mayor parte del tiempo, pero que aún hay un porcentaje significativo de trabajadores que no siempre encuentran el ambiente de trabajo confortable. En conclusión, las cooperativas deben considerar las estrategias para mejorar la relación entre los jefes y los trabajadores, mediante la capacitación y el entrenamiento de los jefes en habilidades de liderazgo, comunicación y empatía. Esto puede producir un impacto positivo en el desempeño y la satisfacción laboral.
Los problemas ambientales, la minería ilegal y la contaminación en el oriente ecuatoriano
Authors: Erazo-Morales Paula Lorena , Esteves-Fajardo Zila Isabel
Published: July 2023

El objetivo general de la presente investigación fue describir los problemas ambientales, la minería ilegal y la contaminación en el oriente ecuatoriano. El desarrollo de la investigación, se realizó desde la perspectiva cuantitativa, y se complementó con un diseño documental-bibliográfico. Lo que permitió, la recogida de información extraída de los diferentes artículos arbitrados, trabajo de grado, entre otros. Además, se realizó una investigación descriptiva. Se concluye que, es preocupante que por los hechos de la minería ilegal y otros problemas ambientales exista la vulneración del ambiente en el oriente ecuatoriano y en otras zonas de la nación, a pesar de contar con la condiciones y normativas legales que contribuyen a la preservación y conservación de la naturaleza. Es necesario que las políticas públicas en materia medio-ambiental deben ser revisadas y adaptadas a los nuevos tiempos contribuyendo al buen vivir.