bluuebunny/crossref_metadata_2025 huggingface dataset:
Pembelajaran Fisika Menggunakan Model Discovery Learning Berbasis Edutainment
Authors: Winarti Wahyu Tri , Yuliani Hadma , Rohmadi Mukhlis , Septiana Nurul
Published: March 2021

Pembelajaran fisika merupakan pembelajaran mengenai  gejala-gejala alam dan berusaha menemukan hubungan antara kenyataan di alam. Perlu adanya model dan metode yang dapat membantu menerangkan gejala alam tersebut dalam proses pembelajaran fisika. Salah satu model yang diharapkan cocok dengan karakteristik pembelajaran fisika yaitu model discovery learning berbasis edutainment. Penelitian ini bertujuan: (1) untuk mendeskripsikan kelebihan dan kekurangan dari model discovery learning berbasis  edutainment; dan (2) untuk mendeskripsikan penerapani model discovery learning berbasis edutainment dalam pembelajaran fisika. Metode pengumpulan data pada penelitian ini adalah studi literatur dan kajian pustaka, data penelitian ini menggunakan jenis data sekunder, kemudian data yang diperoleh tersebut diolah dengan analisis isi. Hasil penelitian menunjukkan bahwa: (1) Model discovery learning berbasis edutainment dapat menjadikan peserta didik aktif dalam kegiatan belajar dan menyenangkan. Namun, memerlukan waktu yang cukup lama dalam pembelajarannya dan kurang efektif digunakan dalam kelas besar; dan (2) Pada pembelajaran fisika, model discovery learning berbasis edutainment digunakan untuk memahami materi yang cukup sulit dengan cara yang menyenangkan.Physics learning is learning about natural phenomena and trying to find the relationship between reality in nature. It is necessary to have models and methods to explain these natural phenomena in the physics learning process. One model that is expected to match physics learning characteristics is the discovery learning model based on edutainment. This study aims: (1) To describe the advantages and disadvantages of the discovery learning model based on edutainment models; (2) To describe the application of the discovery learning model based on edutainment models in physics learning. The data collection method in this research is a literature study and literature review. This research data use secondary data, then the data obtained is processed by content analysis. The results showed that: (1) Discovery learning model based on edutainment could make students active in learning activities because it is fun; however, the learning process requires a long time and is less effective when used in a class with a large number of students; and (2) In physics learning, the discovery learning model based on edutainment is used to understand difficult material in a fun way.
Predictive Markers of Missed Miscarriage
Authors: Orazmuradov Agamurad , Akhmatova Anastasiya , Haddad Khalid , Lopatin Alexander , Bekbaeva Irina , Arakelyan Gayane , Abitova Marianna , Kyrtikov Sergey , Zokirova Nozimabonu , Lukaev Aleksey
Published: March 2021

The aim of this study was to find useful the serological markers for missed miscarriage (MM) in order to predict the outcome of pregnancy. The study included 141 pregnant women aged between 18 and 45 years at gestational age under 11 weeks. All women were divided into 3 groups. Group 1 included 68 women with MM; Group 2 included 43 women with spontaneous miscarriage; Group 3 included 30 pregnant women without pathology. Proteomic analysis of the blood serum was performed using liquid chromatography-mass spectrometry. The results of our study show that immunoglobulin kappa variable 3-15 (KV315) can be considered as the most promising serologic marker for MM in early gestation. The potential role of KV315 as the serological marker is very important for predicting the course of pregnancy.
20(S)-Panaxadiol Enhances Hemostatic Effect on Activated Platelet by Affecting Calcium Signaling
Authors: Zhang He , Su Wenjie , Yang Chunhui , Tang Xiaolei , Pan Daian , Zhang Yuyao , Zhao Daqing , Qi Bin , Li Xiangyan
Published: March 2021

Background: Panax notoginseng (Burk.) F.H. Chen has long been used to stop bleeding for hundreds of years in China. At present, only dencichine and notoginsenoside Ft1 showed the hemostatic effect. Other ingredients from Panax notoginseng need to be further investigated. This study evaluates the hemostatic effect of 20(S)-panaxadiol (PD) and reveals its mechanism. Methods: We performed an in vivo study to measure PD on the hemostatic effect of mouse tail amputation and liver scratch models, and routine blood. Plasma coagulation parameters were measured using a blood analyzer. Platelet aggregation rate and adenosine triphosphate (ATP) release were analyzed by platelet aggregometer. Subsequently, degranulation marker P-selectin (CD62P), PAC-1 (activated GP IIb/IIIa receptor marker), the concentrations of cytosolic Ca2+ ([Ca2+]i) and cyclic adenosine monophosphate (cAMP) were also assessed. Results: PD shorted bleeding time on the mouse tail amputation and liver scratch models and mainly increased blood platelet count in the rats after subcutaneous injection of 4 h. Meanwhile, PD decreased APTT, increased FIB content, and directly induced platelet aggregation. In the absence of Ca2+, PD promoted the increase of [Ca2+]i and ATP, slightly increased CD62P expression and PAC-1 binding of platelets. After the addition of Ca2+, PD treatment markedly promoted platelet activation by releasing ATP level, increasing CD62P expression and PAC-1 binding, and decreasing cAMP level in platelets. Besides, PD increased phosphorylation of phosphoinositide 3-kinase (PI3K), protein kinase B (PKB or Akt), and glycogen synthase kinase 3β (GSK3β) in human platelets. Excitingly, PD-induced changes included platelet aggregation, a decrease of the cAMP content, and the increases of ATP, CD62P and PAC-1, which were significantly reversed by vorapaxar, which showed a similar function as thrombin. Conclusions: PD is an essential hemostatic ingredient in Panax notoginseng for promoting hematopoiesis and thrombopoiesis. PD induces platelet aggregation by affecting calcium signaling and activating PI3K/Akt/GSK3β signaling pathway, which could contribute to the new insight for the treatment of hemorrhagic disease.
Genome-Wide mRNA Profiling Identifies  the NRF2- Regulated Lymphocyte Oxidative Status in Patients with Silicosis
Authors: zhao yingzheng , Xu Guangcui , Li Haibin , Chang Meiyu , Xiong Cheng , Tao Yingjun , Guan Yi , Li Yuchun , Yao Sanqiao
Published: March 2021

BackgroundThe immunomodulatory abnormalities of silicosis are related to the lymphocyte oxidative state. The potential effect of antioxidant therapy on silicosis may depend on the variation in nuclear factor erythroid 2-related factor 2 (NRF2)-regulated antioxidant genes in peripheral blood mononuclear cells (PBMCs). As NRF2 is a redox-sensitive transcription factor, its possible roles and underlying mechanism in the treatment of silicosis need to be clarified.MethodsIn this study, the lymphocyte oxidative state was investigated by evaluating NRF2 expression and NRF2-dependent antioxidative genes in PBMCs from patients with silicosis. Key differentially expressed genes (DEGs) and signaling pathways were identified utilizing RNA sequencing (RNA-Seq) and bioinformatics technology. Gene set enrichment analysis was used to identify the differences in NRF2 signaling networks between patients with silicosis and healthy controls.ResultsThe number of monocytes increased significantly through cytology detection in patients with silicosis. Furthermore, RNA-Seq findings were confirmed using quantitative polymerase chain reaction and revealed that NRF2-regulated DEGs were associated with glutathione metabolism, transforming growth factor-β, and the extracellular matrix receptor interaction signaling pathway in PBMCs from patients with silicosis. The top 10 hub genes were identified by PPI analysis: SMAD2, MAPK3, THBS1, SMAD3, ITGB3, integrin alpha-V (ITGAV), von Willebrand factor (VWF), BMP4, CD44, and SMAD7.ConclusionsThese findings suggest that NRF2 signaling regulates the lymphocyte oxidative state and may contribute to fibrogenic responses in human PBMCs. Therefore, NRF2 might serve as a novel preventive and therapeutic candidate for silicosis.
Adrenal Crisis and Disseminated Intravascular Coagulation Associated With Disseminated Carcinomatosis of the Bone Marrow From Gastric Cancer
Authors: Lee Roland Y , Goldberg Elliott , Malysz Jozef , Li Huili , Shin Benjamin , Chen Xueying
Published: March 2021

Gastric cancer is the third leading cause of cancer deaths worldwide. Disseminated carcinomatosis of bone marrow (DCBM) originating from gastric cancer is rare and associated with poor prognosis. We present the first reported case of gastric adenocarcinoma with DCBM leading to concomitant disseminated intravascular coagulation (DIC) and adrenal crisis refractory to treatment. Computerized tomography of the chest, abdomen and pelvis showed diffuse sclerosis of the axial and proximal appendicular skeleton, suggestive of metastatic disease. Bone marrow biopsy demonstrated infiltrative signet ring cells, consistent with metastatic adenocarcinoma from gastric primary. Laboratory tests showed severe anemia, thrombocytopenia, and coagulopathy, compatible with DIC.
Single Nucleotide Polymorphism Analysis of Pvmdr-1 in Plasmodium Vivax Isolated From Military Personnel of Republic of Korea in 2016 and 2017
Authors: Bong Jin-Jong , Lee Wonsig , Park Qu-Ehn , Noh Kyung Tae
Published: March 2021

Background: Malaria chemoprophylaxis using chloroquine and primaquine has been administered to resident soldiers in the 3rd Army of Republic of Korea (ROK) to prevent malaria infection since the year 1997. Due to mass chemoprophylaxis against malaria, concern exists about occurrence of chloroquine resistance. Herein, we investigated the single nucleotide polymorphisms (SNPs) of the Plasmodium vivax multi-drug resistance protein-1 (Pvmdr-1) gene to monitor the risk of chloroquine resistance.Methods: To evaluate the risk of malaria chemoprophylaxis, SNPs of the Pvmdr-1 gene were analysed in 73 soldiers of the 3rd Army of ROK diagnosed with infection by Plasmodium vivax. Results: Quintuple mutations (G698S, L845F, M908L, T958M, and F1076L) were detected in 73 soldiers. Mutation in the Y541C position was detected in soldiers at a frequency of 1.3% (1/73). In addition, silent mutations were detected at positions 44K, 493L, 529T, and 1233E. Based on these SNPs, Pvmdr-1 sequences of ROK were classified into 6 haplotypes. Phylogenetic analysis showed that the neighbourhood of the 6 haplotypes were Chaina_NB-16 and Papua New Guinea-PNG58 (Figure 1).Conclusions: Genetic- or phenotypic-based chloroquine resistance was not observed. However, various SNPs including a newly identified non-synonymous mutation (Y541C) have been introduced into Plasmodium vivax malaria endemic areas in ROK. Thus, to prevent the emergence of chloroquine resistance, continuous surveillance for SNPs of Pvmdr-1 related with chloroquine resistance is essential in the malaria chemoprophylaxis-executed regions of ROK.
Glial Cells Modulate Retinal Cell Survival in Rotenone-Induced Neural Degeneration
Authors: Tawarayama Hiroshi , Inoue-Yanagimachi Maki , Himori Noriko , Nakazawa Toru
Published: March 2021

Administration of the mitochondrial complex I inhibitor rotenone provides an excellent model to study the pathomechanism of oxidative stress-related neural degeneration diseases. In this study, we examined the glial roles in retinal cell survival and degeneration under the rotenone-induced oxidative stress condition. Mouse-derived Müller, microglial (BV-2), and dissociated retinal cells were used for in vitro experiments. Gene expression levels and cell viability were determined using quantitative reverse transcription-polymerase chain reaction and the alamarBlue assay, respectively. Conditioned media were prepared by stimulating glial cells with rotenone. Retinal ganglion cells (RGCs) and inner nuclear layer (INL) were visualized on rat retinal sections by immunohistochemistry and eosin/hematoxylin, respectively. Rotenone dose-dependently induced glial cell death. Treatment with rotenone or rotenone-stimulated glial cell-conditioned media altered gene expression of growth factors and inflammatory cytokines in glial cells. The viability of dissociated retinal cells significantly increased upon culturing in media conditioned with rotenone-stimulated or Müller cell-conditioned media-stimulated BV-2 cells. Furthermore, intravitreal neurotrophin-5 administration prevented the rotenone-induced reduction of RGC number and INL thickness in rats. Thus, glial cells exerted both positive and negative effects on retinal cell survival in rotenone-induced neural degeneration via altered expression of growth factors, especially upregulation of microglia-derived Ntf5, and proinflammatory cytokines.
Monitoring Urinary Collagen Metabolite Changes Following Collagen Peptide Ingestion and Physical Activity Using ELISA With Anti–Active-Collagen-Oligopeptide Antibody
Authors: Osawa Yoshihiro , Nomura Kaho , Kimira Yoshifumi , Kushibe Seiji , Takeyama Ken-ichi , Nagao Masashi , Kataoka-Matsushita Aya , Koizumi Seiko , Mano Hiroshi
Published: March 2021

Active collagen oligopeptides are bioactive collagen-derived peptides detected by a recently-established ELISA. To facilitate studies of the function and metabolism of these products, this study aims to determine which of these peptides is recognized by a novel anti-ACOP antibody used in this ELISA. We then investigate the effect of collagen peptide (CP) ingestion and exercise on urinary ACOP concentrations in a cohort of university student athletes using colorimetric, LC-MS/MS, and ELISA. We observed that the antibody showed strong cross-reactivity to Pro-Hyp and Gly-Pro-Hyp and weak cross-reactivity to commercial CP. CP ingestion increased the urinary level of ACOP over time, which correlated highly with urinary levels of peptide forms of Hyp and Pro-Hyp. Physical activity significantly decreased the urinary ACOP level. This study demonstrates changes in urinary ACOP following oral CP intake and physical activity using ELISA with the novel anti-ACOP antibody. Thus, ACOP may be useful as a new biomarker for collagen metabolism.
Protective Effect of SCUBE1 on Oxidative Stress-induced Apoptosis in Human Ovarian Granulosa Cells
Authors: Fu Huijiao , Cai Xuzi , Liu Qiwen , Yang Wei , wang xuefeng
Published: March 2021

Background: Apoptosis of ovarian granulosa cells (GCs) is a sign of follicular atresia. This study aimed to explore the role and mechanism of signal peptide, CUB domain, epidermal growth factor-like protein1 (SCUBE1) in protecting GCs from apoptosis induced by hydrogen peroxide (H2O2). Methods: Firstly, the expression of SCUBE1 on the ovaries of humans and mice was analyzed by qRT-PCR, western blot and immunohistochemistry. Subsequently, the H2O2 treated GCs were pretreated with SCUBE1 recombinant protein, and their cell viability and proliferation were detected by Cell Counting Kit-8 (CCK-8) assay. The levels of reactive oxygen species (ROS) and mitochondrial membrane potential (ΔΨm) in the cells were determined by DCFH-DA and rhodamine 123, respectively. The percentage of apoptotic cells was analyzed by flow cytometry after staining with Annexin V/PI. The expression levels of pathway related proteins, such as Bcl-2, Bax, p53, caspase-3, were determined by western blot analysis. Finally, the pathogenicity of SCUBE1 (c.1169C>G, p.P390R) were analyzed based on the software.Results: SCUBE1 was expressed in women of all ages and had the highest expression level in the ovaries in multiple organs and tissues of KM mouse. In vitro cell experiments show that SCUBE1 pretreatment reduced H2O2-induced apoptosis and improved cell viability. SCUBE1 also blocked the production of ROS in cells and improved mitochondrial membrane potential. After SCUBE1 pretreatment, anti-apoptotic protein Bcl-2 expression was upregulated, whereas the expression of the pro-apoptotic proteins Bax, Bax/Bcl-2, Caspase-3, and p53 were downregulated. Analysis of the impact of SCUBE1 (c.1169C >G, p.P390R) mutation from the aspect of mutation pathogenicity; protein stability; and gene haplotype insufficiency, indicated that the p.P390R mutation is significantly pathogenic.Conclusions: This is the first time that the potential role of SCUBE1 in protecting GCs from H2O2-induced damage through the mitochondrial pathways, attributing to POI, is studied. SCUBE1 (c.1169C >G, p.P390R) mutation has significant pathogenicity but the specific harm needs to be confirmed by further studies. Trial registration: Not applicable.
Gingival enlargement in thalassemia patient – A Conjectural Association
Authors: BAIJU CS , Gupta Gunjan , Joshi Karuna , Shagufta  , Gupta N.D
Published: March 2021

Thalassemia is a single gene inherited blood disease. Beta thalassemia major is life threating. It causes abnormality in various organs and oral-facial region. Thalassemia patients are immune-deficient because of iron-overload. Immune system abnormality includes neutrophilic dysfunction and impairment of phagocytosis by the monocyte-macrophage system. Iron accumulation also affects periodontal tissues, which seems to increase the level of cytokines and thus have an enhancing effect on gingival inflammation. This article highlights a peculiar case of gingival enlargement in anterior maxilla and mandible. The patient was known case of a beta-thalassemia major. Blood investigation revealed a lower level of hemoglobin. The patient underwent non-surgical periodontal therapy. Proper periodontal care improves the quality of life in these patients. This case report reinforces the significance of proper history taking with all minor details and the role of patient education in phase I therapy
A Comparative evaluation of serum CRP levels in chronic and aggressive periodontitis patients before and after non-surgical periodontal therapy- a clinical study
Authors: Gupta Shruti , Gupta Ira , Gupta Rohit , Amaranath  B J Janardhana , Goswami Arpita , Singh Deepshikha
Published: March 2021

Aims and Objectives: C-reactive protein is an acute-phase-reactant primarily produced by the liver in response to infection or trauma. Recent studies have demonstrated a correlation between periodontitis and elevated CRP levels. This study aims to relate the serum-CRP level in chronic and aggressive periodontitis patients, before and after periodontal treatment, with healthy controls.

Materials and Method:  A case-control clinical study was conducted with a total of 75 systemically healthy subjects, where 25 subjects were selected in each groups: Group I, Healthy control subjects; Group II, generalized chronic periodontitis patients, and Group III, generalized aggressive periodontitis patients. Serum-CRP levels were quantified by using turbidimetric immunoassay at baseline and 3month post-treatment. Kit used was “TURBILYTE-CRP” (Tulip Diagnostics, Goa, India). In the treatment phase, patients received single visit nonsurgical periodontal treatment, completed within 24hrs under LA for GCP & GAP group.

Results: Mean serum CRP levels were significantly higher in both GCP and GAP groups as compared to the control group at baseline. On comparing the clinical parameters at 3 months post-treatment for GCP & GAP group with control group values, the mean score of serum CRP levels for the GAP group was statistically significant (P<0.001) in comparison to the GCP group, which in turn was statistically significant as compared to control group.

Conclusion: The present study indicates a positive correlation between CRP and periodontal disease severity with particular concern in younger individuals, where it could be a possible underlying pathway in the association between periodontal disease and risk for cardiovascular disease in periodontitis patients.
Risk factors for increased intraocular pressure and eye damage during robotic-assisted prostatectomy
Authors: Lutfarakhmanov I. I. , Galeev I. R. , Lifanova A. D. , Mironov Р. I.
Published: March 2021

Prostate cancer remains the most common urologic malignancy, and robotic-assisted radical prostatectomy makes the most effective treatment option. The special conditions of the surgery (Trendelenburg position) affect the intraocular pressure.

The objective: to systematize new data on changes in intraocular pressure during robotic-assisted radical prostatectomy under various types of general anesthesia. Materials and methods. Publications were reviewed using the PubMed search engine in the electronic databases of Medline, Embase, and Cochrane Library up to August 2020.

Results. A total, 9 studies were included in the review including a randomized controlled one. Robot-assisted radical prostatectomy can be a safe surgery regarding perioperative changes in intraocular pressure and ophthalmic complications.

Conclusions. The review offers the first assessment of changes in intraocular pressure during robotic-assisted radical prostatectomy. Further studies with a longer follow-up period are needed to determine the clinical efficacy and safety of various types of general anesthesia.
Enoxaparin-induced hepatotoxicity: clinical cases and literature review
Authors: Krovko Yu. N. , Shmigelskiy A. V. , Аkhmedov A. D. , Shulgina A. A. , Lukshin V. A. , Usachev D. Yu.
Published: March 2021

Low molecular weight heparins, in particular enoxaparin, have a wide range of applications, including prevention and treatment of deep vein thrombosis.  The most common adverse effects of these drugs are bleeding and thrombocytopenia, but a clinician should be aware of another less common but not less important adverse effect such as an elevated transaminase level. In 2019, we observed two cases of enoxaparin-induced hepatotoxicity. In the first one, enoxaparin 0.4 ml subcutaneously twice a day was prescribed to a 40-year-old woman as a bridge therapy to discontinue warfarin before elective surgery. In the second case, a 27-year-old man received enoxaparin 0.4 ml subcutaneously twice a day for the prevention of deep vein thrombosis. The elevation of transaminase level for more than 3 times above the norm was noted in both patients which required discontinuation of the drug.
Pendidikan dalam Perspektif Hadis (Suatu Kajian Tematik dalam Bulûgh Al-Marâm)
Authors: Khon Abdul Majid
Published: March 2021

The hadiths about education in the book Bulûgh Al-Marâm are entirely found and can fulfill the themes of education today, even though this book is characterized by the law of Fiqh (Fiqhul Hadith). There are 17 hadiths or 1.06% of the total 1596 hadiths with the essential word education (ta'lîm). Educational themes that can be fulfilled are; science components, educators, students, educational materials, learning strategies, and teacher salaries. The hadiths found to discuss the importance of useful knowledge. The prophet in Hadith as in the Quran QS. Thaha / 20: 114 only ordered to pray for more knowledge, not ordered to ask for another. The role of educators as servants of students, namely mediators and facilitators. Educators must always learn and have a democratic attitude. Successful students are those who need knowledge and can develop their talents. Teaching material prioritizes ethics or manners and prayer as the practice of knowledge. Teachers may receive honoraria and even have the right to receive an honorarium if the student's condition is worthy of being charged.
PEMBANGKIT LISTRIK TENAGA GELOMBANG LAUT DENGAN MENGGUNAKAN TEKNOLOGI OSCILATING WATER COLUMN (OWC) DI PERAIRAN MARANA
Authors: Setiyawan Setiyawan , Abdulrahim N.
Published: March 2021

The alternatives to overcome electricity shortage in Indonesia is wave generating. One of the methods conducted in this research is OWC (Oscilating Water Column) based on study area criteria (Marana Village). OWC method can convert ocean wave energy atwave columnoscillationto generate electricity. To be able to produce electricity, this OWC device will train the wave energy through the OWC door hole. This research determine the amount of waves that can be utilized in Marana waters to be converted into units of electricity (watts). The amount of wave height that can be used, depends on the amount of wind that is in the waters of Marana. In addition to wave height, tidal is also needed to know the placement of Oscilating Water Column (OWC) is so that when the tidal water occurs, OWC is still in the condition of the wave. In addition, the bathymetry of the sea is also needed to know at the depth of how placed this OWC. Based on the results obtained from wave forecasting using the 2002-2006 wind data obtained maximum wave height for 5 years is 0.204 m in Year 2003. Which can generate electricity of 0.688 watts. Where from concluded in Marana waters do not have the potential to build Sea Wave Power Plant.
Dampak Bangkitan Lalu-Lintas Kawasan Ekonomi Khusus (KEK) Palu Terhadap Kinerja Perkerasan Jalan (Studi kasus Ruas Jalan Nasional Pantoloan-Tawaeli)
Authors: Hamid A.G. , Bahar T. , Setiawan A.
Published: March 2021

Palu City is designated as a Special Economic Zone for the development of the region's economic potential, as an integrated logistics center and mining processing industry in the Sulawesi economic corridor to encourage equity and increase and accelerate the economy. The performance of road pavements will decrease as the road service ages. The impact of the existence of Palu Special Economic zone resulted in the rise/pull of new traffic movements that burdened the National Pantoloan-Tawaeli road section, This research was conducted under the guidance of Pavement Design Manual 2017, where from the results of the research there was traffic loading due to the existence of the Palu Special Economic Zone amounted to 997, 761, 256 CESAL, resulting in a reduction in the life of road services by 10 years.
Pengaruh Pengetahuan Keselamatan dan Kesehatan Kerja (K3) Terhadap Perilaku Pekerja dan Kecelakaan Kerja Pada Proyek di DS LNG Kabupaten Banggai Propinsi Sulawesi Tengah
Authors: Suartana P. , Mandagi R.J.M. , Wilar D.
Published: March 2021

In association with the potential risks of work accidents in the implementation of construction work, the knowledge of K3 on a construction project is now a fundamental requirement. Aspects of K3 itself will not be able to be run as it should without any intervention from management in the form of a planned effort to manage it (safety management), which is often called the Occupational Safety and Health Management System (SMK3). This research aims to know effects of the knowledge of K3 on the behavior of construction workers as viewed from several aspects related to K3  such as the influence of knowledge variables K3 together to the behavior of construction workers, the effect of knowledge variables K3 partially on the behavior of construction workers and the effect of worker's behavior on work accident.This research were conducted in four construction companies which executed works given by the local government of Luwuk Banggai Regency in 2016. The research approach used in this research is survey method and regression and correlation analysis method having samples of 129 workers. Based on statistical test of hypothesis test, the test result of each K3 knowledge variable shows that all the variables tested (5 K3 knowledge variables ie devinition and initiation K3/X1, K3/X2 management system, personal protector K3/X3, facilities and infrastructure K3/X4, K3/X5 risk) has a strong correlation to worker behavioral variables (Y1). This is evidenced by the correlation numbers R> 0.8 and the determination (r2)>0.7. However, based on the results of simultaneous test (F test) to know the correlation of the five variables of K3 knowledge together to the variable of worker behavior (Y1), the result of statistical test on the simultaneous test shows that in t test (partial) only 2 K3 Good correlation to worker behavior (Y1) that is variable of personal protective device (X3) and K3 risk (X5). According to these two test, it revealed that linear multiple regression result in an equation: Y=0,318X3+0,557X5+1,613 with determinant coefficient (R2) = 71.4 % which means that the model resulting having very good performance.
Detection of Radiolucid Lesions in Digital Panoramic Radiographs
Authors: Rodrigues Emilly K. F. , Santos Milena T. M. , Marinho Sandra A.
Published: March 2021

This study evaluated the presence of radiolucid lesions in digital panoramic radiographs from the archives of the State University of Paraiba (UEPB) Diagnostic Imaging Clinic, performed in 2017. After surveying the radiographs performed by the service in that year, those with radiolucent lesions were selected, being excluded those with poor quality and with patient positioning errors. By means of a structured form, the characteristics observed in the radiographs were recorded by a single trained and calibrated observer. The analysis took place through descriptive statistics and all ethical aspects were respected. There was a low prevalence (14.2%) of radiographs with radiolucent lesions, which mainly affected young female patients. These lesions were small in size, located predominantly in the posterior periapical region of the mandible, with a unilocular aspect, being associated with a posterior tooth, mainly premolar. Inflammatory lesions were the most prevalent, with a presumptive diagnosis highlighting the predominance of abscesses followed by cysts/granulomas. The dentigerous cyst was the third most prevalent odontogenic lesion, occurring in its entirety in females. Odontogenic keratocysts and Stafne's bone cavity were also detected.
A Rare Complications of Sickle Cell Disease: Empyema and Chronic Subdural Hematoma
Authors: Miraulle Tien Yu Song , Synèse Bemora Joseph , D’assise Masina Ndalana , Charles Rasolonjatovo Emilson , Clément Andriamamonjy , Rabarijaona Mamiarisoa , Willy Ratovondrainy
Published: March 2021

Sickle cell disease is a hemoglobinopathy responsible for many complications that are sometimes frightening. Brain damage is part of one of the complications that can affect the vital and/or functional prognosis of patients.    We report two cases of neurological complications, patients with known homozygous sickle cell disease, admitted to the Resuscitation Service of the JRA University Hospital for neurological deficit of recent appearance. One presented a spontaneous bilateral chronic bilateral subdural hematoma, and the other an extradural empyema diagnosed on brain scan. The patients benefited from a neurosurgical intervention with favorable postoperative outcomes, marked by an improvement in neurological symptoms. This form of complication is relatively rare in patients with sickle cell disease. It is favoured by repeated vaso-occlusive crises responsible for vascular fragility following repeated ischemia and inflammatory phenomena. The surgical indication depends on the clinical condition and the radiological aspect
“五倫”並不排斥契約
Authors: FANG Xudong
Published: March 2021

LANGUAGE NOTE | Document text in Chinese; abstract in English only.Professor Fan Ruiping proposed that in the Confucian view, the basis of the family relationship is family affection rather than a contract. This judgment of the Confucian family view is based on a comparative perspective on civilization. However, not only husband and wife, but also monarch and minister, were established on the basis of the contract. Although Confucianism lacks the strong utilitarian intention of Western utilitarians, it is not without the contractual consciousness of equality and mutual benefit.DOWNLOAD HISTORY | This article has been downloaded 3 times in Digital Commons before migrating into this platform.
Disorientation, Dislocation and Displacement in Kiran Desai's the Inheritance of Loss
Authors: Mambrol Nasrullah
Published: March 2021

The Inheritance of Loss is more a book about the migrant experience. The plot is essentially about disorientation as a result of dislocation and displacement and the accompanying lack of sympathy resulting in feeling of being dispossessed. The characters feel the pull of the margin all the time thereby struggling to decide between the choice of moving out or remaining there. A sense of alienation and loss is always the immigrant's lifelong companion though they left their shores for a sense of economic or social or professional fulfillment.
Performance Of Milkfish (Chanos chanos) Cultured by Different Stocking Density in Floating Net Cages Lake Batur, Trunyan Village, Bali
Authors: Sukmawantara Gede Dwi , Arthana I Wayan , Kartika Gde Angga Raka
Published: March 2021

Lake Batur is the largest lake in the island of Bali. Lake Batur is widely used by the community in the aquaculture sector, namely floating net cage cultivation. The research aims to determine the influence of different stocking density on the growth rate and survival rate of the milkfish (Chanos chanos) in the 4 x 1 meters floating net cages in Lake Batur, Trunyan village. Data collection was done every two weeks during two months observation, from January 2020 – March 2020. The research used a complete random design consisting of three treatments and three replications of each treatment, which the treatment A of 15 fish/0.25m3, treatment B of 20 fish/0.25m3, and the treatment C of 25 fish/0.25m3. Measurements of fish length, fish weight, and water quality were done in situ. The results showed that the difference in stocking density had no effect on the absolute length, but those difference had an effect on the specific growth rate (SGR) and the survival rate of the fish. Treatment B resulted a maximum value of the growth rate, with an absolute length value of 0.69 ± 0.115cm/2 month and SGR 1.02 ± 0.095%/day. The fish survival rate at treatment A resulted in the highest value of 89 ± 3.46%/2 month. The value of water quality during the study were temperature of 25.9 ± 0.8oC, DO of 8.3 ± 0,1 mg/L, pH of 9.4 ± 0.2, and TDS of 995.5 ± 70.8 ppm.
Identifikasi Spesies Streptokokus ?-Hemolisis Hasil Isolasi dari Nasal dan Tonsil Babi dengan Uji Basitrasin
Authors: Suardana I Wayan , Dinarini Ni Made Ayu Aryati , Sukrama I Dewa Made
Published: March 2021

Streptokokosis merupakan penyakit yang disebabkan oleh kelompok bakteri Streptococcus sp dengan manifestasi berupa poliartritis, septicemia, dan meningitis. Strain Streptokokus ?-hemolisis merupakan salah satu bakteri patogen yang dapat masuk melalui luka, abrasi, makanan atau saat sistem imun melemah. Penelitian ini bertujuan untuk mengetahui keberadaan bakteri Streptokokus ?-hemolisis pada babi yang diternakkan di peternakan rakyat Desa Punggul dan Desa Bongkasa, Kecamatan Abiansemal, Badung, Bali. Studi ini menggunakan 47 isolat berasal dari swab mukosa hidung dan tonsil. Semua sampel dikultur pada media agar darah dilanjutkan dengan penanaman pada media Brain Heart Infussion (BHI), kemudian dilakukan pewarnaan Gram, uji katalase dan uji biokimiawi. Setelah didapati isolat positif Streptokokus ?-hemolisis, dilanjutkan dengan pengujian basitrasin untuk mendeteksi strain Streptococcus pyogenes dan strain beta hemolisis lainnya. Hasil penelitian menunjukkan dari 47 isolat yang diuji, sebanyak 8 isolat (17%) merupakan bakteri presumtif  Streptokokus ?-hemolisis. Hasil uji basitrasin terhadap ke-8 isolat tersebut ditemukan 3 isolat (37,5%) menunjukan zona hambat basitrasin dan dikelompokkan sebagai S. pyogenes, sedangkan 5 isolat (62,5%) lainnya tidak menunjukan zona hambat dan dikelompokan sebagai Streptokokus ?-hemolisis non-pyogenes.
Total Bakteri Feses Ayam Petelur pada Berbagai Periode Pemeliharaan
Authors: Baskara Dewa Putu Pradipta , Besung I Nengah Kerta , PG Ketut Tono
Published: March 2021

Penelitian ini bertujuan untuk mengetahui jumlah total bakteri yang diisolasi dari feses ayam petelur pada berbagai periode pemeliharaan. Sampel yang digunakan adalah feses ayam petelur sehat dengan total keseluruhan 24 sampel menggunakan metode tuang. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL). Data yang diperoleh diuji dengan Uji Beda Nyata Terkecil (BNT). Hasil penelitian menunjukkan jumlah total bakteri pada ayam petelur fase starter sebanyak 52,83x107 CFU/ml, ayam petelur fase grower sebanyak 208,50x107 CFU/ml, ayam petelur fase developer sebanyak 409,5x107 CFU/ml, dan ayam petelur fase layer sebanyak 208x107 CFU/ml. Dapat disimpulkan pada setiap tingkatan fase umur jumlah total bakteri pada feses ayam petelur berbeda nyata.
Karakteristik Personal dalam Memoderasi Pengaruh Penganggaran Partisipatif dan Ambiguitas Peran pada Senjangan Anggaran
Authors: Dharmawan Yoana , Wirakusuma Made Gede
Published: March 2021

This study aims to determine the role of personal characteristics in moderating the effect of participatory budgeting on budgetary slack and to determine the role of personal characteristics in moderating the influence of role ambiguity on budgetary slack. Data used is primer data, the analysis technique used in this study is Moderated Regression Analysis. The results of the analysis address personal characteristics which weaken the effect of participatory budgeting on budgetary slack. This shows that with good personal characteristics, participatory budgets will be able to reduce budgetary slack events. Personal characteristics weaken the influence of role ambiguity on budgetary slack. This shows that good personal characteristics, the role ambiguity will be reduced and will able to reduce the budgetary slack.

Keywords: Personal Characteristics; Participatory Budgeting; Role Ambiguity; Budgetary Slack.
Pengaruh Pendapatan Asli Daerah, Belanja Modal dan Indeks Pembangunan Manusia
Authors: Hobrouw Yustine Asnad , Suaryana I Gusti Ngurah Agung , Asri Dwija Putri I G.A.M.
Published: March 2021

This study aims to determine empirically the effect of local revenue on the increase in the human development index in West Papua province and to empirically determine the effect of capital expenditure on the increase in the human development index in West Papua province. The data analysis technique used is multiple linear regression analysis. Based on the results of the analysis, it is known that the Original Regional Income has a positive and significant effect on the increase in the District / City Human Development Index in West Papua Province. This shows that an increase in Regional Original Income (PAD) will tend to increase the Human Development Index. Capital expenditure has a positive and significant effect on increasing the District / City Human Development Index in West Papua Province.

Keywords: PAD; Capital Expenditures; Human Development Index.
Dekonstruksi dalam Novel Ranah 3 Warna Karya Ahmad Fuadi
Authors: Marzuq Ahmad , . Zuriyati , Gomo Attas Siti
Published: March 2021

This study aims to find other meanings for the novel Ranah 3 Warna. Researchers use deconstruction theory to uncover and see the other side of the character Alif who is described as a character who is persistent, tough and unyielding. This research uses literature study method to collect and provide data to be analyzed. The data source in this research is the text of the novel Ranah 3 Warna by Ahmad Fuadi, first printed in January 2011 by PT Gramedia Jakarta. The data was collected by using the method of reading repeatedly carefully against the manuscripts that were the object of the research. The data analysis used in this research is descriptive analysis technique by describing the data which is then followed by the analysis. Based on the text analysis and other meanings carried out on the novel Ranah 3 Warna, it is revealed the figures of people who have had a big influence in Alif's life. Among them, Kyai Rais, Ayah, Bang Togar and Randai. Other analysis results reveal that Alif is easily offended, is less grateful and forgets the services of his little friend Randai who has sacrificed a lot for his survival overseas. In addition, Alif also has a character that does not accept reality and is ambitious in achieving what he wants.
Koperasi Simpan Pinjam Bali Artha Guna dalam Bingkai Budaya Masyarakat Modern di Bali
Authors: Sunaryo Fransiska Dewi Setiowati , Rai Wahyuni Anak Agung Ayu
Published: March 2021

The purpose of this study is to reveal several problems related to the application of modern management in the management of Savings and Loans Cooperatives (KSP), especially in the KSP Puskopdit Bali Artha Guna (BAG). Puskopdit Bali Artha Guna is a secondary KSP which until the end of 2018 has 20 primary cooperative members with 58,520 individual members spread across Bali. Cooperatives as a form of business entity engaged in the economy have a management structure that is somewhat different from other business entities. To achieve the goals of cooperatives, it is necessary to apply a good management system, namely implementing management functions. Some of the problems described in the discussion include 1) in what ways the development of modern management has been carried out at KSP Puskopdit Bali Artha Guna; 2) how is the implementation of modern management practices in cooperatives in facing today's business competition; 3) what benefits can be generated for the community, especially cooperative members in Bali. The method used in this research is descriptive qualitative with the method of collecting data through literature studies and in-depth interviews. In general, members of the Puskopdit Bali Artha Guna cooperative have digitized and implemented modern management in their operational systems to remain competitive in the millennial era who are familiar with technology, so that they are able to compete with other financial institutions.
Noun Form of Address of Characters in the 21 Jump Street Movie
Authors: Dewi Luh Ledi Ruscita , Indrawati Ni Luh Ketut Mas
Published: March 2021

This study is aimed to identify the types of noun form of address and describing the function of noun form of address applied in the movie. The data of this study was taken from a movie entitled 21 Jump Street as the primary data. The data was collected by documentation method and note taking technique. A qualitative method was used to analyze the data. It means the data was described based on theories applied in this study. The theory proposed by Braun was used to analyze the types of noun form of address. Whereas, the theory proposed by Brown and Gilman was used to analyze the function of noun form of address applied by characters in the movie. The results found five types of noun form of address, namely; names term (first name, last name and nickname), kinship term, title, occupational term, terms of endearment. This study does not find any data related to the abstract noun because this movie does not have any scenes which describe the abstract quality of the addressee, such as in the kingdom or court. Moreover, the function of noun form of address terms to show solidarity becomes the highest occurrences in the movie.
Representasi Fashion Era Taisho-Showa pada Film Animasi Kaze Tachinu Karya Hayao Miyazaki
Authors: Megawati Ni Luh , Sendra I Made , Ari Sulatri Ni Luh Putu
Published: March 2021

This research is entitled “Fashion Representation of Taisho-Showa Era in Kaze Tachinu Animation Film by Hayao Miyazaki”. Fashion style transition from wasou to yosou was found in Taisho-Showa Era. This research aims to discover the form, function, and meaning of fashion in the Taisho-Showa era which are depicted in the film. This research used literature study method and the referral method for the data accumulation, descriptive analysis method for data analysis and for analysis results presented with informal method. For the theory, this research used literary anthropology theory by Poyatos (2008), fashion form theory by Pendergast and Tom (2004), fashion function theory by Barnard (1996), and semiotics theory by Barthes (1964). Based on the analysis results, can be seen that fashion’s form that represent in Taisho-Showa era are divided into two category, first is wasou which consists of hakama, haori, kimono, mandarin shirt, obi, shimada, comb, geta, tabi, and zori, and the second one is yosou that consists of men’s suit, stockings, trench coat, men’s hats, short hair for woman, waved hair for woman, clutch purse, patent leather shoes, and high heeled boots. For the fashion’s function that found in this research are 1) protection function; 2) politeness and concealment function; 3) communication function; 4) individualistic expression; 5) social worth or status; 6) economic worth or status; 7) magical-religious condition; and 8) recreational functions. And for the fashion’s meaning in the Taisho-Showa era, in denotation is refers to the form and design of fashion, while the connotation of fashion is formed by the influence of social and cultural values in Japanese society.
Reckoning with COVID, Racial Violence, and the Perilous Pursuit of Transparency
Authors: Monahan Torin
Published: March 2021

This essay reflects on the many upheavals of the past year and their implications for critical scholarship on surveillance. The COVID-19 pandemic, anti-science policies, radicalized white supremacists, police killings of people of color, and the resurgence of the racial justice movement all inflect surveillance practices in the contemporary moment. In particular, today’s polarized political landscape makes it difficult to condemn surveillance in the service of the public good, but irrespective of one’s goals or intentions, the embrace of transparency carries its own risks. Transparency, and scientific vision more broadly, is an extension of the Enlightenment and subsequent scientific revolution, which from the start sought to advance knowledge and consolidate white power through the violent subjugation of nature, women, and racial minorities. One fundamental risk of valorizing transparency is that doing so occludes the ways that relations of domination are indelibly encoded into surveillance systems and practices. Given this, I argue that the project of decolonizing surveillance inquiry should now be our primary focus as a field.
Limits on entropic uncertainty relations
Authors: Ambainis Andris
Published: March 2021

We consider entropic uncertainty relations for outcomes of the measurements of a quantum state in 3 or more mutually unbiased bases (MUBs), chosen from the standard construction of MUBs in prime dimension. We show that, for any choice of 3 MUBs and at least one choice of a larger number of MUBs, the best possible entropic uncertainty relation can be only marginally better than the one that trivially follows from the relation by Maassen and Uffink for 2 bases.
Computational distinguishability of degradable and antidegradable channels
Authors: Rosgen Bill
Published: March 2021

A channel is degradable if there exists a second channel that maps the output state of the channel to the environment state. These channels satisfy the property that the output state contains more information about the input than the environment does. A complementary class of channels is the antidegradable channels, which admit channels that map the environment state to the output state of the channel. In this paper we show that the computational problem of distinguishing two channels remains -complete when restricted to these classes of channels. This is shown using a construction of Cubitt, Ruskai, and Smith that embeds any channel into a degradable channel, and a related construction for the case of antidegradable channels.
The Source and Transmission of COVID-19
Authors: Chetan Patel
Published: March 2021

SARS-CoV-2 is recognized as a public health concern by WHO & declared it as a pandemic on 11th of March 2020. Over 4,43,03,684 people affected with the death of 11,72,955 worldwide till 28 of October 2020. The most affected country is the USA with a total no. Affected case of 90,39,170 then INDIA with a 7,99,03,222 no. of cases and death of 1,20,054 people. SARS-CoV-2 thought to commonly spread via respiratory droplets from an infected person form during talking, coughing, sneezing, etc. Several cases are found without a travel history to affected area leading to a strong possibility of community transmission. Transmission can be divided into two parts. Direct through airway droplets (respiratory droplets), through body fluid and secretions ex. Saliva, faeces, tears etc. and mother to child (ex. Breastfeeding). Indirect fomites or surfaces (objects which get infected by the patient) or objects which are uses for a checkup of an infected person. A significant number of these modes found or unfamiliar with evidence are neglected, thus is requires to specify and delineate them. Despite the fact that the writing could conceivably make reference to these courses, it is essential to underscore them as it might help in avoidance and treatment.