bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Perceived Social Support and Resilience in Predicting the Mental Health of Healthcare Professionals During the COVID-19 Pandemic: A Study from Indonesia
Authors: Siswadi Ahmad Gimmy P. , Shabrina Arina , Djunaidi Achmad , Iskandarsyah Aulia
Published: December 2022

Background:

The COVID-19 pandemic had a tremendous impact on Healthcare Professionals (HCPs). Social support and resilience were seen as protective factors for mental health problems. This study aimed to investigate the role of perceived social support and resilience in predicting Healthcare Professionals’ mental health during the outbreak in Indonesia.

Methods:

A digital self-reported survey was completed by 202 HCPs (143 women and 59 men) during the outbreak. A cross-sectional study was applied, and participants were recruited through a purposive sampling technique. The online survey collected information on sociodemographic, perceived social support, resilience, and mental health problems. Perceived social support was measured by The Multidimensional Scale of Perceived Social Support (MSPSS), resilience by the Connor-Davidson Resilience Scale (CD-RISC)–10, and mental health problems by the Self-Report Questionnaire (SRQ). Multivariate regression was applied to analyze the data.

Results:

Results indicated that a high resilience score was associated with low scores for depression, anxiety, and somatoform symptoms (β = -4.72, p = 0.000). On the contrary, perceived social support did not predict mental health or PTSD symptoms (β = -0.56, p = 0.412).

Conclusion:

Considering the role of resilience in reducing mental health problems, we suggest government and health authorities design an intervention program to increase HCPs’ resilience.
The Present Status of Respectful Maternity Care during Labor and Childbirth in Jordan: A Cross-sectional Study
Authors: AbuAlrub Salwa , Abu-Baker Nesrin N. , Abu Baker Muhammed , Abu Musameh Hanan
Published: December 2022

Background

Exploring the status of respectful maternity care (RMC) during labor and childbirth helps in determining the quality of maternity care. Therefore, this study aimed to investigate the perception of pregnant women about RMC that they received during labor and childbirth and to evaluate the determinants of RMC perception.

Method

A cross-sectional descriptive design was used in this study. A convenience sample of 310 participants from two major hospitals in northern Jordan completed the RMC questionnaire. Thereafter, multiple regression was performed to identify the determinants of RMC perception.

Results

The mean score of all the items of the questionnaire was 2.83 out of 4 (SD = 0.33), which indicated that the women experienced a moderate level of RMC. The lowest mean scores were obtained for the quality of healthcare (mean= 2.63, SD= .38), 48.7% and 56.8% of the participants indicated that they were not allowed to move or eat and drink during the first stage of labor, respectively. In addition to the right to information and informed consent (mean= 2.67 ± 0.54), 56.8% of the participants revealed that staff did not introduce themselves. Women with high family income or assistance from a midwife reported significantly higher RMC scores compared to those with low family income or those tended by doctors (p ≤ 0.05).

Conclusion

Immediate action is needed to improve and support RMC as a critical component of maternal care by adopting standardized measures, and training healthcare providers to practice the code of ethics as a core component of RMC.
Neuropilin-2 Inhibits Drug Resistance and Progression of Melanoma
Involving the MiR-331-3p Regulated Cascade
Authors: Liu Dandan , Yang Jing , Xie Qun , Zhang Ruirui , Hu Qiang , Shan Chao , Li Xiaohan
Published: December 2022

Background:

MicroRNAs (miRs) are small noncoding RNAs that are crucial in the
development and progression of tumours. Melanoma is an aggressive form of skin cancer and is
resistant to most of the chemotherapeutic agents. However, the role of miRs in melanoma remains
poorly studied.

Objective:

The work aimed to demonstrate that miR-331-3p is downregulated in melanoma
against the benign melanocytic nevi.

Methods:

RT-PCR analysis was performed for the expression of proteins; cell proliferation and
wound healing assays were carried out. Flow cytometry study was conducted for cell cycle analysis;
colony formation assay was performed by soft agar method. For developing a tumour xenograft
model, nu/nu mice were selected.

Results:

Up-regulation of miR-331-3p in melanoma cells decreased cell proliferation, cell migration,
and also drug resistance. Over-expression of miR-331-3p resulted in suppression of NRP2
and up-regulation of E-cadherin levels. Moreover, the levels of MDR1, ABCG-2, and ABCG-5
were decreased. However, the knockdown of NRP2 demonstrated similar effects as that of miR-
331-3p overexpression in tumour cells. Overexpression of miR-331-3p caused significant inhibition
of tumour growth and its metastasis in mice model of melanoma, which was associated with
depletion of NRP2 protein and increased expression of E-cadherin. However, the effects of miR-
331-3p on the migration, cell proliferation, and self-renewal were overturned by the upregulation
of NRP2, which also resulted in the inhibition of E-cadherin and overexpression of MDR-1,
ABCG-2, and ABCG-5.

Conclusion:

The findings point out the key role of miR-331-3p in the progression and drug resistance
of melanoma involving NRP2.
Phytochemical, Medicinal, and Green Approaches of Allamanda cathartica L.: A
Mini Review
Authors: Prakash Sharma Ishwar , Balkrishna Acharya , Saini Akansha , Bhandari Rachna , Arya Vedpriya
Published: December 2022

Allamanda cathartica L. belongs to the family Apocynaceae and is a traditionally valuable medicinal plant that has been commonly used in the
traditional medicinal system and contributes to the native healthcare system in various parts of the world. This plant is renowned for its
antibacterial and anticancer effects and its usage in the treatment of jaundice, diabetes, hypertension, and polio. All of the economically and
medicinally essential plant parts of this species are used in the preparation of a potent cathartic. This review focused on and intended to highlight
the most current knowledge about A. cathartica, including its important ethnomedicinal, modern medicinal, and phytochemical potential along
with its green approaches. This plant has been extensively used in herbal medicine and has various important phytopharmacological properties.
The modern green technological approaches of this plant enhance agricultural productivity when its various nanoparticles are applied in fields that
perform antimicrobial, antipathogenic activities. Nanoparticles serve as carriers for the delivery of drugs and as disease targets in contemporary
medicine. This plant has recently been involved in modern medicine as a threat to cancer, which is a significant accomplishment for modern
medical science. Hence, A. cathartica is an important plant that can be useful to cure various ailments and could be useful in modern science with
its green approaches. We must further investigate this plant's bioactivities to determine the mode of action.
EFEK ANTIBAKTERI EKSTRAK ETANOL BUAH ASAM JAWA (TAMARINDUS INDICA L.) TERHADAP PERTUMBUHAN BAKTERI PREVOTELLA INTERMEDIA
Authors: Wijaya Fatta , Kurnia Calvin , Kurniawati Sugiaman Vinna
Published: December 2022

Latar Belakang : Periodontitis merupakan penyakit inflamasi yang disebabkan oleh mikroorganisme, berkembang dari waktu ke waktu yang diawali dengan akumulasi plak gigi. Salah satu mikroorganisme yang memiliki hubungan dalam terjadinya periodontitis adalah Prevotella intermedia, yang merupakan bakteri gram negatif yang sering diisolasi pada plak gigi. Buah asam jawa (Tamarindus indica L.) mengandung metabolit sekunder yaitu senyawa flavonoid, tanin, saponin, alkaloid, triterpenoid, dan fenolik yang berperan sebagai antibakteri. Tujuan: Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri buah asam jawa (Tamarindus indica L.) terhadap pertumbuhan bakteri Prevotella intermedia dengan mengukur Kadar Hambat Minimal (KHM) dan Kadar Bunuh Minimal (KBM). Metode: Metode yang digunakan dalam penelitian ini adalah metode dilusi, sebanyak 10 perlakuan dengan konsentrasi 100%, 50%, 25%, 12,5%, 6,25%, 3,13%, 1,56%, 0,78%, kontrol positif dengan chlorhexidine glukonat 0,2%, kontrol negatif menggunakan akuades. Hasil: Data dianalisis menggunakan uji statistik KruskallWallis sebagai pengganti uji statistik One way ANOVA karena tidak berdistribusi normal. Hal ini menunjukkan pvalue < 0,05 yang menunjukkan penurunan jumlah koloni bakteri Prevotella intermedia terhadap beberapa konsentrasi yang diuji. KHM terjadi pada konsentrasi 3,125% dan KBM pada konsentrasi 6,25%. Kesimpulan: Ekstrak etanol buah asam jawa (Tamarindus indica L.) memiliki efek sebahai antibakteri terhadap Prevotella intermedia dengan KHM pada konsentrasi 3,125% dan KBM pada konsentrasi 6,25%. Kata Kunci: Asam Jawa, Antibakteri, Dilusi, Periodontitis, Prevotella intermedia
PENGARUH LAMA WAKTU PERENDAMAN DAN KONSENTRASI SEDUHAN KOPI ARABIKA TERHADAP JUMLAH PELEPASAN ION NIKEL PADA KAWAT ORTODONTI STAINLESS STEEL
Authors: amalia nasution mutia , Sulistyawati Erna , Sheila Syarifah
Published: December 2022

Latar Belakang : Korosi merupakan suatu peristiwa penurunan kualitas bahan logam karena adanya reaksi elektrokimia dengan lingkungan yang ditandai dengan pelepasan ion logam terutama ion nikel dan kromium. Proses korosi dapat dikurangi atau diperlambat salah satunya dengan cara menambahkan inhibitor. Kafein merupakan salah satu inhibitor yang berasal dari senyawa organik. Tujuan: Untuk mengetahui perbedaan jumlah pelepasan ion nikel pada kawat ortodonti Stainless Steel yang direndam dalam saliva dan seduhan kopi arabika dengan waktu dan konsentrasi yang berbeda. Metode Penelitian: Penelitian ini mengunakan 25 kawat ortodonti stainless steel berbentuk rectangle dengan ukuran 0,016 inci x 0,022 inci sepanjang 4 cm yang direndam dalam saliva buatan selama 2 minggu dan ditambahkan seduhan kopi arabika konsentrasi 20% dan 10% dengan waktu tepat 4 jam dan 8 jam sebelum 2 minggu perendaman. Jumlah pelepasan ion Nikel dilakukan dengan menggunakan alat AAS (Atomic Absorption Spectroscopy). Hasil: Analisa data menggunakan uji one way ANOVA menunjukkan adanya perbedaan yang signifikan antara jumlah pelepasan ion nikel pada kawat ortodonti setelah perendaman dalam seduhan kopi arabika. Kelompok dengan perendaman 10% larutan kopi dengan waktu 8 jam perendaman menunjukkan hasil nilai pelepasan ion yang paling kecil dibandingkan kelompok perlakuan lain. Kesimpulan; perendaman dalam seduhan kopi arabika dengan konsentrasi lebih rendah dan waktu perendaman yang lebih lama lebih efektif menghambat jumlah pelepasan ion. Kata kunci: ion nikel, stainless steel, kopi arabika
PENGARUH PENAMBAHAN HIDROKSIAPATIT KITOSAN PADA KEKERASAAN PERMUKAAN KOMPOSIT RESIN NANOHYBRID
Authors: Chair Effendi Muhammad , Padmarini Areta
Published: December 2022

Latar belakang: Hidroksiapatit kitosan (HA/Cs) memiliki komposisi dan struktur kristal apatit yang menyerupai jaringan keras manusia seperti struktur gigi dan tulang. Hidroksiapatit kitosan (HA/Cs) mempunyai kelebihan dan sering digunakan sebagai restorasi gigi karena ketahanan abrasi yang lebih baik. Objektif: Tujuan penelitian ini untuk mengetahui perbedaan kekerasan resin komposit nanohibrid dengan resin komposit nanohibrid setelah penambahan HA/Cs. Metode: Sampel dikelompokkan menjadi 4 kelompok berbeda yaitu kelompok kontrol resin komposit nanohybrid, dan kelompok resin komposit nanohybrid dengan penambahan kitosan masing-masing sebesar 3%, 5%, dan 7% yang kemudian diuji dengan Vickers Microhardness Tester. Sampel juga diuji dengan XRD untuk melihat karakterisasi partikel kristal dan SEM-EDX untuk melihat morfologi sampel dan mengidentifikasi unsur yang terkandung. Hasil: Hasil uji SEM menunjukkan ukuran rata-rata morfologi komposit nanohybrid Ha/Cs adalah 1 µm, sedangkan hasil EDX rata-rata rasio Ca/P pada resin komposit nanohibrid dengan penambahan kitosan hidroksiapatit adalah 2,53. Analisis data menggunakan uji One Way Anova menunjukkan nilai signifikansi p < 0.01, sehingga terdapat perbedaan kekerasan permukaan pada kelompok kontrol yang memiliki nilai 63,70 HV dan kelompok perlakuan dengan penambahan HA/Cs sebanyak 3%, 5%, dan 7% yang memiliki nilai pada kelompok perlakuan berturut-turut adalah 78,15 HV, 80,9 HV dan 83,57 HV. Kesimpulan: Penambahan HA/Cs pada bahan restorasi gigi komposit nanohybrid dapat meningkatkan kekerasan permukaan bahan. Kata kunci: hidroksiapatit kitosan, komposit nanohibrid, komposit nanohibrid kitosan, kekerasan permukaan
PENGARUH SUSU TERHADAP KEKERASAN ENAMEL GIGI: STUDI LITERATUR
Authors: Sutanti Viranda , Lely Rachmawati Yuanita , El Milla Lalita , Cahaya Ningtyas Devi
Published: December 2022

Latar Belakang: Karies gigi merupakan masalah kesehatan gigi dengan proporsi terbanyak di Indonesia, yang terjadi karena adanya proses demineralisasi. Proses demineralisasi dapat dicegah lebih lanjut menggunakan susu sebagai agen antikariogenik sekaligus agen remineralisasi. Proses demineralisasi dan remineralisasi gigi dapat dideteksi melalui perubahan kekerasan enamel gigi. Tujuan: Mengetahui pengaruh susu terhadap kekerasan enamel gigi. Metode: Tinjauan literatur dengan pencarian melalui beberapa database elektronik berdasarkan kata kunci yang telah ditetapkan, kemudian dilanjutkan dengan menyeleksi literatur dengan metode PRISMA. Hasil: Berdasarkan 10 artikel yang dianalisis dalam studi literatur ini, diketahui bahwa susu berpengaruh terhadap kekerasan enamel gigi dengan nilai peningkatan yang berbeda-beda. Jenis susu yang dapat digunakan sebagai agen remineralisasi antara lain susu sapi, susu kambing, dan susu kerbau. Susu yang paling banyak terbukti dalam meningkatkan kekerasan enamel adalah susu sapi. Kesimpulan: Susu menjadi agen remineralisasi dengan meningkatkan kekerasan enamel gigi, tetapi kemampuan remineralisasi oleh susu ini tidak dapat mengembalikan nilai kekerasan enamel awal sebelum terjadi demineralisasi. Kata Kunci: Susu, remineralisasi, kekerasan enamel gigi
Lazer & COVID-19: Corpos Proibidos e Alterações nas Dinâmicas de Lazer nas Cidades da Maia (Portugal) e Curitiba (Brasil)
Authors: Castro Fernanda , Baptista Maria Manuel , Rechia Simone
Published: December 2022

Este artigo pretende colocar no cerne de uma reflexão crítica, política e teórica as alterações nas dinâmicas de lazer urbano, nomeadamente, nas cidades da Maia (Portugal) e Curitiba (Brasil), fruto da pandemia de COVID-19. Consideramos, sob a lente dos estudos culturais, que a COVID-19 constitui uma oportunidade fundamental e única para compreender os fenómenos humanos em torno de uma situação sanitária limite que acionou e continua a acionar processos biopolíticos e mecanismos de controlo tecnológico na mobilidade e lazer dos corpos. Este artigo destaca a forma como a pandemia diluiu as fronteiras entre o doméstico, trabalho e lazer, muito em serviço e benefício do sistema neoliberal e capitalista. Recorrendo a uma recolha etnográfica (realizada entre março de 2020 e junho de 2021), à análise qualitativa de dados e aos contributos teóricos de Foucault (1979/1998, 1996/1999, 1975/2002, 1994/2006, 2010a, 1976/2010b), Deleuze (1992, 1995), Certeau (1980/1994, 1993/1995), Haraway (1997, 2018), Braidotti (2020) e Mbembe (2003/2018) numa articulação muito particular com o locus, o contexto social e político dos espaços e as consequências pandémicas que atuam de uma forma muito específica e insidiosa em cada um dos espaços, foi possível verificar que o lazer é, na pandemia, (re)valorizado e reivindicado como direito fundamental em face da regulação, controlo e disciplina dos corpos. Os dados indicam que os sujeitos reclamam a mobilidade e os espaços perdidos, desafiando a ordem, a lei e a autoridade implementadas. Evidenciou-se, igualmente, uma pertinente articulação teórica e empírica entre as políticas sanitárias implementadas e as performances disruptivas e subversivas observadas, que apresentam, no tempo e no espaço, uma gradação e progressão da subversão dos corpos nos parques de lazer, locus privilegiado da liberdade.
Effect of a fruit and vegetable drink on muscle recovery after resistance exercise
Authors: Pinheiro Maria Hipólito Almeida , Fonseca Luan Pereira , Oliveira Jeann Carlo Gazolla de , Castro Gotardo do Carmo de , Santos-Rezende Vitor Hugo , Gouveia Mariana da Silva , Viveiros Bruna Dias , Martins Eliane Maurício Furtado , Franco Frederico Souzalima Caldoncelli , Ferreira-Júnior João Batista
Published: December 2022

Objective: To evaluate the effect of fruit and vegetable drink supplementation on muscle recovery after resistance exercise. Methods: 11 men performed two experimental conditions 12 days apart, in a randomized and double-blind manner: 1) Supplementation with Smoothie - drink based on pineapple, mint, sage, ginger, and pomegranate; and 2) Placebo - drink based on artificial pineapple juice. Participants ingested 400 mL of Smoothie or Placebo drinks daily for 9 days, starting one week before performing the exercise (10 sets of 10 unilateral maximum repetitions in leg press 45º). The perceived subjective recovery (PSR), thickness (MT) and soreness (MS) in the anterior thigh muscles, and maximum isometric strength (MIS) were measured before, 24, 48, 72, and 96 h after exercise. Results: There was a reduction in MIS and PSR and an increase in MS 24 h after exercise (p < 0.05). In both situations, MIS returned to baseline values at 72 h (p > 0.05), while PSR and MS returned to baseline values 96 h after exercise. There was no change in MT (p > 0.05). Conclusion: Supplementation with pineapple, mint, sage, ginger, and pomegranate drinks did not accelerate muscle recovery over 96 h after the 45º leg press exercise.
Defensa y Reorganización Socioespacial de los Fraccionamientos de Interés Social de la Periferia de Tijuana
Authors: Urbalejo Castorena Olga Lorenia
Published: December 2022

El artículo es un estudio de la ciudad, con una perspectiva cultural. Se centra en los fraccionamientos de interés social, ubicados en la periferia este de Tijuana, Baja California, México. Se analiza cómo los residentes se organizan y reorganizan sus espacios ante la inseguridad que viven, porque han quedado insertos en un contexto de violencia, de desplazamiento -por el mercado inmobiliario fronterizo-, de segregación urbana y del abandono e invasión de viviendas. Se propone que, dadas las condiciones descritas en los fraccionamientos (algunos con 20 años de antigüedad), se reconstruyen los entornos desde una urbanización defensiva.
La cadena de valor de hortalizas en la región Caribe de Colombia
Authors: Martínez Reina Antonio María , Correa Álvarez Ender Manuel , Tofiño Rivera Adriana Patricia , Cordero Cordero Carina Cecilia , Silva Acosta Gabriel Ernesto , Rodríguez Pinto María del Valle , Romero Ferrer Jorge Luis , Grandett Martínez Liliana María , Tordecilla Zumaqué Lilibet , Orozco Guerrero Alfonso Rafael
Published: December 2022

El tema central de esta investigación es el enfoque de cadenas productivas, ya que este es de tipo integral e incluye los procesos de producción en finca hasta el consumidor final. En este libro, se realiza una revisión conceptual desde los aportes de Davis y Goldberg (1957), pasando por la escuela francesa con Malassis y sus enfoques. Se trata de recrear los elementos teóricos de la cadena de valor, como es el caso de la producción de hortalizas en la región Caribe de Colombia. Se pude establecer que la integración es baja y como respuesta presenta baja competitividad; además, hay presencia de brechas tecnológicas que hacen menos eficiente el proceso. Lo interesante del trabajo es que se construyó con aportes de los diferentes actores de la cadena de producción-consumo, y una vez identificados los puntos críticos que frenan el desarrollo de la cadena estos actores propusieron un plan de acción para su integración y el mejoramiento de la competitividad. Este trabajo es una invitación a entender y aplicar el enfoque de cadenas productivas y quedan demostradas sus ventajas y su nivel de inclusión, sin tener en cuenta el tamaño de la producción o el estatus que ocupe dentro de la sociedad.
Estimating County-Level Overdose Rates Using Opioid-Related Twitter Data: Interdisciplinary Infodemiology Study
Authors: Cuomo Raphael , Purushothaman Vidya , Calac Alec J , McMann Tiana , Li Zhuoran , Mackey Tim
Published: December 2022

Background

There were an estimated 100,306 drug overdose deaths between April 2020 and April 2021, a three-quarter increase from the prior 12-month period. There is an approximate 6-month reporting lag for provisional counts of drug overdose deaths from the National Vital Statistics System, and the highest level of geospatial resolution is at the state level. By contrast, public social media data are available close to real-time and are often accessible with precise coordinates.

Objective

The purpose of this study is to assess whether county-level overdose mortality burden could be estimated using opioid-related Twitter data.

Methods

International Classification of Diseases (ICD) codes for poisoning or exposure to overdose at the county level were obtained from CDC WONDER. Demographics were collected from the American Community Survey. The Twitter Application Programming Interface was used to obtain tweets that contained any of the 36 terms with drug names. An unsupervised classification approach was used for clustering tweets. Population-normalized variables and polynomial population-normalized variables were produced. Furthermore, z scores of the Getis Ord Gi clustering statistic were produced, and both these scores and their polynomial counterparts were explored in regression modeling of county-level overdose mortality burden. A series of linear regression models were used for predictive modeling to explore the interpretability of the analytical output.

Results

Modeling overdose mortality with normalized demographic variables alone explained only 7.4% of the variability in county-level overdose mortality, whereas this was approximately doubled by the use of specific demographic and Twitter data covariates based on a backward selection approach. The highest adjusted R2 and lowest AIC (Akaike Info Criterion) were obtained for the model with normalized demographic variables, normalized z scores from geospatial analyses, and normalized topic counts (adjusted R2=0.133, AIC=8546.8). The z scores of the Getis Ord Gi statistic appeared to have improved utility over population-normalization alone. In this model, median age, female population, and tweets about web-based drug sales were positively associated with opioid mortality. Asian race and Hispanic ethnicity were significantly negatively associated with county-level burdens of overdose mortality.

Conclusions

Social media data, when transformed using certain statistical approaches, may add utility to the goal of producing closer to real-time county-level estimates of overdose mortality. Prediction of opioid-related outcomes can be advanced to inform prevention and treatment decisions. This interdisciplinary approach can facilitate evidence-based funding decisions for various substance use disorder prevention and treatment programs.
Anticoagulant use to treat VTE (venous thromboembolism) in pregnancy: a review
Authors: Purwandityo Ayuningtyas Galuh , Muhammad S. Finnegan  , Mukarromah D. Putri  , Muya Saroh  , Nindita Rachmania  , Riandita G. Putri
Published: December 2022

Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a medical condition that occurs when a blood clot forms in a deep vein that major cause of pregnancy-related maternal death. As pregnancy progresses, the risk of hypercoagulability increases, fibrinogen, factors VII, VIII, X and VWF (Von Willebrand Factor), plasminogen activator inhibitor-1, plasminogen activator inhibitor-2 are increases and 40-60% protein S decreases. Therefore, anticoagulant drugs are the mainstay of therapy for patients with VTE. The review aimed to select the best anticoagulant for pregnancy women with VTE. A scoping review was used. The type of articles reviewed were original articles obtained from four electronic journal databases published within 2012-2021. The main therapeutic agent recommended for use in the prevention and treatment of VTE in pregnancy is low molecular weight heparin (LMWH). LMWH has better bioavailability than other anticoagulants, has a lower risk of maternal bleeding, thromboembolic, thrombocytopenia and osteoporosis. The use of LMWH is actually better, more comfortable and safety for patients.
Knowledge of hypertension and its therapy in lay people
Authors: Simatupang Abraham , Sitompul Fransiska , Kurniaty Linggom , Djojosaputro Mulyadi , Lumbantobing Romauli , Silaban Hertina
Published: December 2022

Hypertension is one of the non-communicable diseases that is becoming a global health problem. Hypertension  can be identified by systolic blood pressure  of 140 mmHg and diastolic 90 mmHg . Uncontrolled hypertension can lead to  complications such as stroke, ischemic heart disease, heart attack, heart failure,  kidney failure, blindness, etc. According to Basic Health Research  2018  ( Ris et  Kesehatan Dasar 2018/Ris kesdas 2018) the prevalence of hypertension for >18  years  old wa s 8.4%, and through measurements taken in health care facilities by  34.1%. Prevalence in the city was 34.4%, in the village was 33.7%, while according  to gender 31.3% f or  male and 36.9%  for  female. The study  aimed to  find out the  knowledge and awareness of laypeople on hypertension and its therapy. This was  a cross-sectional online study with 11 questions. Respondents were recruited from  social media groups. The  results showed 5 00 respondents (62.8 % female and  37.2  % male) involved in this study . The most  common  age range was 21-40 years (36.2  %),  followed by  41-55 years (38.2%) , and the least was 56-65 years old (18.4%). Seventy-two percent of respondents did not have hypertension, and 9% said they  did not know. Fifty-three percent of respondents knew about the value of high  blood pressure, and 89%  of the  respondents said hypertension should be treated  regularly. The most hypertension complications answered by respondents were  stroke (40%), heart attack (26%) , and heart failure (16%). Amlodipine was the  most mentioned by  the  respondents,  and  the second was ACE-inhibitor. However,  omeprazole and omega-3  were  also mentioned as anti-hypertension. Genetic s and  a  high salt diet were risk factors that many respondents chose. In  conclusi on, the  r espondents have a good understanding  of hypertension. Information related to  behaviour is needed to discontinue the increasing prevalence.
The effects of Curcuma xanthorrhiza rhizome simplicia and Camellia sinensis green tea in a patient with chronic hepatitis B infection: a case report
Authors: Ismail Sjarif , Fikriah Ika , Tandirogang Nataniel , Kosala Khemasili
Published: December 2022

The hepatitis B virus (HBV) causes acute and chronic liver infections which can be treated by using interferon and antiviral. However, the treatment is relatively expensive. We reported here a case of a patient with chronic hepatitis B who had negative seroconversion without interferon (IFN) and antiviral treatment after herbal consumption. A retrospective investigation showed that the patient consumed Curcuma xanthorrhiza rhizome and Camelia sinensis green tea.  These herbs were widely both in vitro and in vivo studied for their effects against HBV infection, although the clinical studies are limited. This case reported the effect of C. xanthorrhiza rhizome and C. sinensis green tea consumption in a patient with chronic hepatitis B. A female patient with chronic hepatisis B infection at the age of 32 y.o. had been taking neuro vitamins regularly for a year before infection detected. She was an asymptomatic patient with normal limits liver function, positive HBsAg and negative anti-Hbs. At the age of 45, she started taking C. xanthorrhiza rhizome simplicia equivalent to 5mg of curcumin twice daily and drinking C. sinensis green tea regularly. Six years later, HBsAg was not detected and her liver function remained within normal limits and Anti-HBs were detected 5 years later. In conclusion, the consumption of C. xanthorrhiza rhizome and C. sinensis green tea can against chronic hepatisis B infection by eliminate HBV dan induce anti-HBs.
PERBANDINGAN BEBAN KERJA LAMA WAKTU PELAYANAN MAHASISWA PPDS 1 DAN DPJP DALAM PELAYANAN PASIEN DI RUMAH SAKIT
Authors: Guntur Surya Alam  , Laksono Trisnantoro  , Darwinto
Published: December 2022

Background: RSUP dr Sardjito, as the primary teaching hospital of FK UGM received many PPDS1. PPDS 1 makes a significant contributionto patient care. PPDS1 at work has not been considered a hospital worker. Meanwhile, PPDS1 has the right as a temporaryofficial hospital worker while taking specialization education.Objective: This study aims to determine differences in the workload.Methods: This is observational research with direct observation of the length of time for DPJP and PPDS1 service activities accordingto the type of activity. The research subjects were PPDS1 from KSM General, KSM Pediatric Surgery, KSM Urology, KSM Pediatrics atvarious levels. Data analysis was carried out by compiling and calculating the group average of invasive and non-invasive medicalprocedures and the average of all.Results: The extended workload of PPDS1 and DPJP student services in pediatric surgery services carried out by red pin residentsis approximately 35%, yellow pin residents and 25%, green pin residents 25, and DPJP about 15%. In general surgery services,about 28% red residents, 24% yellow pin residents, 25% green pin residents, and 23% DPJP. In urology services, about 28% red pin residents, 25% yellow pin residents, 28% green pin residents, and 19% DPJP. UPA residents with red pins are 8%, yellow pin residentsare 23%, green pin residents are 59%, and DPJP is 10%. During the pandemic, the proportion of service time, in general, was 82% held by residents.Conclusion: The workload for red pin residents is 24%, yellow pin residents 24%, green pin residents 34%, and DPJP 18%. Duringthe pandemic, the proportion of surgical service time, in general, was carried out by residents. Service responsibility remains with DPJP even though the length of direct service to patients is only 18% on average.
MEKANISME KOORDINASI GUGUS TUGAS PERCEPATAN PENANGANAN COVID-19 DALAM PENANGGULANGAN PANDEMI COVID-19 DI KABUPATEN X PROVINSI SUMATERA BARAT
Authors: Putri Z.A. Prima , Alim Syahirul , Sulistyo Dwi Handono
Published: December 2022

Background: Coordination is key to the success of disaster management when many parties are involved. However, in carryingout coordination in District X, it is known that there are obstacles, so coordination has not run as it should.Objective: This study aims to explore cross-sectoral coordination (COVID-19 Response Acceleration Task Force) in dealing with theCOVID-19 pandemic in the X Regency. Methods: This is qualitative descriptive research with seven informants from BPBD and X District Health Office. Data was collected through in-depth interviews with transsectional data collection, which only captures the situation at a specific time of the entire longitudinal phase of the disaster, precisely when the COVID-19 Omicron variant developed. Data validation was done by triangulation of sources. Results: The mutual adjustment mechanism has been made by holding meetings to discuss developing issues and compiling. In addition, non-formal communication is also carried out through Whatsapp groups. The direct supervision mechanism carried out by the head of the task force is monitoring and evaluation based on reporting in each implementing field through in-person or online meetings. The process of standardisation mechanism was not carried out because the activities within the task force were deemed to have been integrated with the duties of each regional apparatus institution, so it was sufficient to refer to the guidelines that had been prepared at the central level as a form of standardised activity. Conclusion: The dominant coordination mechanism carried out during the COVID-19 pandemic disaster by the task force in X Regency was mutual adjustment and direct supervision.
MÜZİK TANIMA TEKNOLOJİSİ (MRT) VE ÇEVRİMİÇİ SAĞLAYICILARI
Authors: GÜRBÜZ Tuba
Published: December 2022

Teknolojinin günümüzdeki kadar gelişim göstermediği zamanlarda radyo veya müzik kanalları aracılığıyla müzikler ve sanatçılar tanıtılırdı. Günümüzde ise ses sinyali işlemedeki gelişimler ve mobil teknolojiler, algoritma işleyicilere müzik tanıma uygulamaları oluşturma fırsatını sundu. Müzik keşfetmenin ve dinlemenin gittikçe basit ve ulaşılabilir olduğu bu noktada dinleyicilerin daha önce duymadıkları ya da beğendikleri müzikleri kolaylıkla bulmaları sağlanmış oldu. Herhangi bir mekanda, radyoda, mağazada duyulan müzikleri bulmak için özellikle akıllı telefonlara yüklenerek daha pratik kullanımı olan bu sağlayıcılar genellikle çevrimiçi kullanıma uygun olarak ücretli ve ücretsiz olmak üzere iki farklı seçenek ile tasarlandı. En çok kullanılan çevrimiçi sağlayıcılardan bazıları şunlardır: Shazam, SoundHound, Musixmatch, MusicID, Soly, Genius. Bu sağlayıcılardan en popüler olanı ise Shazam’ dır. Bu sağlayıcının çalışma prensibine göre bir dinleyici ortamda çalan müziği duyduğunda ve cep telefonunu kullanarak Shazam hizmetini aradığında, çalınan müzikten elde edilen 15 saniyeye kadar ses örneği, ardından parçanın adı ve sanatçısı SMS metin mesajı yoluyla kullanıcıya geri gönderilmektedir. Bu sayede kullanıcı çok hızlı bir şekilde müziğe ulaşıp dilerse ulaştığı müzikleri bir çalma listesine dönüştürebilmekte ve Youtube Music ile şarkının videosunu izlemeye olanak da sağlamaktadır. Spotify, Google Play Müzik ve Apple Music entegrasyonu da mevcuttur. Aynı zamanda çevrimdışı da çalışabilen bu uygulama hafızasına kaydettiği müzikleri internet bağlantısı olduğu anda tanımlayabilmektedir.
Quantum Methods for Neural Networks and Application to Medical Image Classification
Authors: Landman Jonas , Mathur Natansh , Li Yun Yvonna , Strahm Martin , Kazdaghli Skander , Prakash Anupam , Kerenidis Iordanis
Published: December 2022

Quantum machine learning techniques have been proposed as a way to potentially enhance performance in machine learning applications.
In this paper, we introduce two new quantum methods for neural networks. The first one is a quantum orthogonal neural network, which is based on a quantum pyramidal circuit as the building block for implementing orthogonal matrix multiplication. We provide an efficient way for training such orthogonal neural networks; novel algorithms are detailed for both classical and quantum hardware, where both are proven to scale asymptotically better than previously known training algorithms.
The second method is quantum-assisted neural networks, where a quantum computer is used to perform inner product estimation for inference and training of classical neural networks.
We then present extensive experiments applied to medical image classification tasks using current state of the art quantum hardware, where we compare different quantum methods with classical ones, on both real quantum hardware and simulators. Our results show that quantum and classical neural networks generates similar level of accuracy, supporting the promise that quantum methods can be useful in solving visual tasks, given the advent of better quantum hardware.
Energy transition as a factor influencing energy legislation: Overview of the International Scientific and Practical Conference, Moscow, Institute of State and Law of the Russian Academy of Sciences, June 20, 2022
Authors: Gabov Andrey V. , Zinkovsky Sergey B. , Lizikova Marina S.
Published: December 2022

The article provides an overview of the International Scientific and Practical Conference “Energy Transition as a Factor of Influence on Energy Legislation”, held on June 20, 2022 at the Institute of State and Law of the Russian Academy of Sciences, co-organized by the Faculty of Law of Lomonosov Moscow State University, Peoples’ Friendship University of Russia, Perm State National Research University, Belgorod State National Research University, and Ulyanovsk State University. The authors describe the main areas of the sections’ activities of the conference, where a comprehensive discussion was given to the issues of rethinking the energy transition in terms of the changed realities, the role and transformation of legal regulation in the framework of the energy transition, legal challenges of ensuring relations in the energy sector, impact of relations on institutions and other branches of law in the energy sector, etc.
Problems and prospects for the development of local self-government in the Russian Federation and foreign countries: The all-Russian conference with international participation, Moscow, RUDN, April 25-29, 2022
Authors: Chikhladze Levan T. , Komlev Evgeny Y.
Published: December 2022

On April 25-29, 2022, an All-Russian conference with international participation “Problems and Prospects for the Development of Local Self-Government in the Russian Federation and Foreign Countries” was held at the Law Institute of the Peoples’ Friendship University of Russia on the basis of the Department of Municipal Law. More than 200 scientists and practicing lawyers from the Russian Federation and foreign countries took part in the Conference. The Conference has acquired a traditional character and is being held for the sixth time. The 2022 conference was marked by a significant increase in the number of participants from different Russian regions, mostly by state and municipal employees. The additional relevance of the conference was caused by the ongoing municipal reform in Russia, designed to concretize the provisions of the 2020 constitutional reform. Besides reports by leading scientists and practitioners, the Conference included a student section “Young Scientist”, as well as a scientific seminar in Spanish on the topic “Decentralization in the framework of Peruvian constitutionalism”. Presents a general description of the conference, and the contents of the plenary meetings and sessions.
The Soviet Union as a composite state structure: education, development trends and causes of disintegration
Authors: Eremyan Vitaliy V.
Published: December 2022

This article is devoted to a critical comparative-legal analysis of the process of formation, development, transformation and disintegration of the first multinational political-territorial entity with a republican form of government of the “Soviet” type, which over time has become a clear example for such complex European states as Yugoslavia and Czechoslovakia. This theme is unique not only in terms of solving the ethnic issue, but also as the “model” of territorial structure since the basis of one federation, the Union of Soviet Socialist Republics, formed another federation, the Russian Soviet Federative Socialist Republic, which integrated, along with traditional administrative units, national political-territorial entities in the form of autonomous republics, regions, and districts. The article emphasizes the fact that one of the consequences of the appearance on the political map of the Soviet Union, which defeated Nazi Germany and its numerous satellites in World War II, was not only the formation of “popular democracy” countries and the so-called “socialist camp” that existed for over forty years and represented a civilizational alternative to the capitalist path of social development, but also the collapse of the colonial system and acquisition of independence and sovereignty by the peoples inhabiting the regions of Africa, Asia, and the Middle East. The Soviet model of the state structure and democracy institutions as antipodes to bourgeois populism and liberal demagogy facilitated an accelerated transition from declarations of constituent and constitutional documents proclaiming human and civil rights and freedoms to their practical implementation in the economic and political sphere in countries that had associated themselves with Western-style democracy; it resulted in a more socially oriented role of state and its structures. The Soviet experience clearly demonstrates what real results the state and society can achieve in solving the women's issue, elimination of total illiteracy, and growth of the well-being of citizens. At the same time, manifestations of authoritarianism and totalitarianism that took place at certain stages reveal that the power mechanism was subject not only to voluntaristic tendencies or official personification, but also to relapses into a personality cult, one of the most negative consequences of state disintegration and local civil wars within its former territory.
The Supreme Court of the RSFSR as a legal form of the supreme judicial authority: to the 100th anniversary of the Supreme Court of the Russian Federation
Authors: Burdina Elena V. , Fomina Lilia Yu.
Published: December 2022

The 100th anniversary of the highest court instance of Russia determines the relevance of studying the Supreme Court of the RSFSR as a historical and legal phenomenon, formed as the highest judiciary authority on fundamentally different organizational approaches than before. The article studies certain specifics of the highest instance of Russia’s judiciary, including legal forms of its organization, activities of the Supreme Court of the RSFSR, structural intra-system relationships, and its place and role in the development of Russia’s statehood. The research offers analysis of theoretical concepts and judicial legislation during the preceding period between the two judicial reforms (of 1864 and of 1922). It aims at revealing certain features of the legal model of the Supreme Court of the RSFSR in 1922 as the first created national form of an organizationally autonomous court of the highest judicial instance in terms of its place and role in the system of Soviet justice. The research methodology is based on comparative-legal and historical-legal approaches. The author refers not only to legal acts, but also to publications of the party and Soviet leaders of the first years of the Soviet power, devoted to the issues of formation of a unified judicial system and its supreme body. The prerequisites for the formation of the Supreme Court of the RSFSR associated with requests for stability and clarity of the rule of law, uniformity of judicial practice in the conditions of the New Economic Policy have been highlighted. The article draws conclusions concerning the legal status of the Supreme Court of the RSFSR, highlights its features as the highest level in a unified judicial system, and determines the legal nature, the place and the role of the Supreme Court of the RSFSR in the system of judiciary, where it was endowed with organizational and managerial powers in respect of people’s investigators, collegium of defense counsellors, bailiffs and public notary offices.
The Civil Code of the RSFSR 1922: features of birth and happy fate
Authors: Kuznetsov Mikhail N.
Published: December 2022

Is dedicated to identifying conceptual legal problems related to the conditions and prospects of “revolutionary expediency” in the process of developing the provisions of the Civil Code of the RSFSR of 1922. The legal paradigm of that time was subjected to a profound transformation based on the ideas of “national property”, “class interest”, “Soviet power”, etc. Understanding the historical, socio-political and cultural processes allows to analyze the norms of the so-called proletarian law. It is established that the adoption of the Civil Code of 1922 was preceded by many years of titanic work of a huge number of highly professional pre-revolutionary lawyers who had drafted the Civil Code of Russia by 1914; later, the norms were lightly powdered with the class proletarian consciousness and taken as the basis (more than 400 of them in total) for the Civil Code of the RSFSR of 1922. The provisions of this code effectively operated until 1964, when the new Civil Code of the RSFSR was adopted. It was the code of “victorious socialism”, that have survived the abolition of the NEP (the New Economic Policy), industrialization and collectivization of the country, Constitution of 1936, Great Patriotic War and, finally, building of socialism in a single country. Thus, the adoption of the Civil Code of the RSFSR in 1922 became an epochal event in the life of the peoples of the multinational country, which, in terms of significance of its impact on Russian civilization and the entire world, can be compared with “Corpus iuris Romani”.
Model of the Soviet criminal law codification: methodological, legal and technical features
Authors: Trikoz Elena N.
Published: December 2022

Researched process of theoretical preparation and practical experience in developing the first Soviet criminal code. It reveals the special significance, legal accessibility and partial continuity of certain provisions and constructions of the RSFSR Criminal Code of 1922, whose centenary is being celebrated this year by the Russian historical-legal and criminological community. The authors emphasize the advantages of legal codification projects, scientific doctrine (legalistic and sociological schools) and post-Russian Revolution law-enforcement practice for consistent codification by means of elaboration and adoption of drafts under the scheme: Code of Statutes / Code - Guiding principles - Republican code - basic Union code. The article analyzes the key provisions of the General and Special parts of the Republican Penal Code of 1922. It notes their keen political focus, class character of the penal system and their descending ladder, elaboration of crime from formal to substantive, the concept of potential danger and the analogy of law, paradoxical humanization by consolidating the system of social protection and non-custodial measures, new excluding circumstances, and juvenile system of penalties for minors. The research employs the system-structural, comparative-historical and functional methods, as well as special methods of technical and legal analysis, dogmatic interpretation and description of legal events and processes in specific historical circumstances of Soviet Russia in 1920s.