bluuebunny/crossref_metadata_2025 huggingface dataset:
RELATIONSHIP BETWEEN INTERNAL ENVIRONMENT ANALYSIS AND QUALITY OF BANKING SERVICE APPLIED RESEARCH IN RAFIDAIN AND RASHID BANKS
Authors: Chetheer Mezeal Wafaa
Published: October 2020

Purpose of the Study: This study aims to improve the level of services provided by business organizations and then achieve the objectives they seek.

Methodology: The questionnaire was adopted to execute the applied part of the examination, which was dispersed to the objective example so as to incorporate and gather the important information, and afterward prepared to utilize strategies and techniques by which to recognize the reactions of people who have taken their perspectives regarding the matter of the exploration, utilizing the program (SPSS). v.17) for factual investigation, where various measurable devices and strategies, for example, rates, emphasess, number juggling midpoints, and connection coefficients were chosen to ascertain the measurable markers identified with every poll.

Main findings: The research found that there is a critical effect of the elements of the interior condition on the nature of banking administration five measurements and this outcome is normal, particularly as the two banks are portrayed by acceptable execution in banking and have extraordinary intensity among different banks.

Applications of this study: Environmental analysis is one of the most important steps of strategic planning, which gives business organizations a clear vision about the amount of change in the factors and variables of the environment in which they live.

Originality/Novelty of the study: In fact, there is no clear and specific definition of what can mean the internal environment of the organization may be due to the difference of business organizations in their internal components in terms of size and nature of the activity, potential, and circumstances, and nevertheless writers and researchers tried to give a general perception of the concept of the internal environment of the organization.
Stability Indicating Liquid Chromatographic Method for the Simultaneous Determination of Rosuvastatin and Ezetimibe from Pharmaceuticals and Biological Samples
Authors: KURBANOĞLU Sevinç , ESİM Ozgur , KOSE Cansel , SAVAŞER Ayhan , OZKAN Yalcin , USLU Bengi , ÖZKAN Sibel
Published: October 2020

Fixed dose combinations of ezetimibe and rosuvastatin are well known to provide significantly superior efficacy to rosuvastatin alone in lowering total cholesterol, and triglyceride levels. Therefore, in this recent work, we prepared fixed dose (10mg/10mg) ezetimibe and rosuvastatin tablet formulations, and a simple, selective and we established and validated rapid chromatographic method for the sensitive and simultaneous determination of rosuvastatin and ezetimibe. We performed the separation on Zorbax SB-C18 (100 mm x 4.6 mm, 3.5 µm particle size) column at 30 oC with a mobile phase that has a composition as water containing 0.1% H3PO4:methanol:acetonitrile (50:25:25 v/v/v) at 1.2 mL/min flow rate. We further performed validation studies according to ICH guidelines. Furthermore, we exposed rosuvastatin and ezetimibe to degradation conditions. We plotted peak area vs. concentration graphs for rosuvastatin and ezetimibe and used for defining the linearity of the detector response. In this suggested method, we observed linear relationships varying from 0.05 to 50 µg/mL for ezetimibe concentrations and from 0.05 to 25 µg/mL for rosuvastatin concentrations. We found the limit of detection values for rosuvastatin and ezetimibe as 0.006 and 0.008 µg/mL, respectively. Moreover, we further used the established method for to the analysis of ezetimibe and rosuvastatin from real spiked samples of rabbit serum.
Exercises in Travel Writing and Literary Tourism: A Teaching and Learning Experiment
Authors: Potočnik Topler Jasna
Published: October 2020

The book entitled »Exercises in Travel Writing and Literary Tourism – A Teaching and Learning Experiment« emerged as a result of experimental project work in teaching English during the subject English in Tourism – Higher Level 1 at the Faculty of Tourism in Brežice, University of Maribor. This approach included teaching in the classroom, research in libraries and at home, and field work. The collection brings eight very different texts on Travel Writing and Literary Tourism by Master's students of Tourism, who were free in choosing the topic of the texts, their styles and the titles . The field of Travel Writing is significant, not only as its own discourse, a tourism trend and a tool of branding and embedding attractions and/or destinations, but also as a tool of teaching and learning a foreign language, which, along with upgrading specific language knowledge, encourages curiosity, research, creativity, reflection and self-development.
Literary Tourism in Krško: Exploring the Famous Scholar Janez Vajkard Valvasor and his House in Krško
Authors: Majerič Marina
Published: October 2020

Literary Tourism is one of the global tourism types on the market, which has its different patterns. This paper is based on secondary data and information about Literary Tourism, and it examines the city of Krško and the role of its most famous literary figure, the great scholar Janez Vajkard Valvasor (1641 - 1693). Krško is a town situated in eastern Slovenia, most recognisable because of its Nuclear Power Plant, literary places and figures such as Janez Vajkard Valvasor, Josipina Hočevar and Vladimir Štoviček. The paper explores Literary Tourism, its connection to Krško, and Janez Vajkard Valvasor as an important literary figure who lived and died in this area. The paper concludes with a discussion based on a personal travel experience through the literary places of the city of Krško.
РЕГУЛИРОВАНИЕ ВОСПРОИЗВОДИМОСТИ ПАРАМЕТРОВ ПОЛИМЕРНЫХ РЕЗИСТОРОВ ПРИ ПОВЫШЕННЫХ ТЕМПЕРАТУРАХ
Authors: Минакова Наталья Николаевна , Ушаков Василий Яковлевич
Published: October 2020

Актуальность работы обусловлена тем, что резистивные полимерные материалы активно применяются в различных электротехнических устройствах. Разнообразные электротехнические устройства изготавливаются из наполненных техническим углеродом каучуков по хорошо освоенной промышленной технологии из доступного сырья. Дальнейшее увеличение масштабов их применения сдерживает сложность выбора компонентов для обеспечения требуемых электрофизических свойств. Разброс параметров, связанный с многокомпонентностью структуры, увеличивает стоимость и сырья для изготовления готовых изделий, и технологии. Цель: оценка возможности улучшения воспроизводимости свойств в серии электротехнических изделий для конкретных условий эксплуатации за счет рецептурных приемов. Проблема усугубляется многокомпонентностью структуры, которая затрудняет обеспечение стабильности и воспроизводимости электрофизических свойств. Для обеспечения возможности использования результатов в промышленных технологиях электротехнические изделия и образцы изготавливались из композиционных материалов, которые отличались концентрацией, маркой электропроводящего компонента, видом полимера. Методы: инструментальные измерения электрофизических характеристик резистивных полимерных композиционных материалов, дисперсионный, регрессионный и корреляционный анализы. Результаты. Определены закономерности изменения коэффициента вариации и величины температурного коэффициента сопротивления от концентрации электропроводящего наполнителя (технического углерода), вида каучука при нагреве постоянным и переменным током в диапазоне приложенного напряжения до 1000 В. Разработаны рекомендации по повышению однородности структуры полимерных композиционных материалов в условиях их эксплуатации при повышенных температурах. Их применение способствует сокращению используемых ресурсов (энергии, материалов, времени) благодаря повышению воспроизводимости величины объемного электрического сопротивления при нагреве в процессе эксплуатации электротехнических изделий.
ОБОСНОВАНИЕ РЕГЛАМЕНТА ПРОХОДКИ ПАРАЛЛЕЛЬНЫХ ВЗАИМОВЛИЯЮЩИХ ВЫРАБОТОК В НАПРЯЖЕННЫХ ТРЕЩИНОВАТЫХ СКАЛЬНЫХ МАССИВАХ
Authors: Харисов Тимур Фаритович , Балек Александр Евгеньевич , Озорнин Иван Леонидович
Published: October 2020

Актуальность исследования обусловлена необходимостью учета взаимного влияния выработок, сооружаемых в напряженных трещиноватых массивах скальных пород, с целью сохранения устойчивости сближенных выработок в процессе их строительства и эксплуатации. Целью исследования является оценка размеров зоны деформирования, образующейся вокруг одиночной горизонтальной выработки в процессе ее строительства, с последующим обоснованием типов и параметров крепи, обеспечивающей их устойчивость. На основании результатов экспериментально-аналитических исследований процессов деформирования системы «крепь–массив», которые были получены и накоплены на протяжении 50 лет в процессе строительства выработок в массиве хромитовых месторождений Донского ГОКа, выполнена оценка напряженно-деформированного состояния породного массива в масштабах шахтного поля и обоснована геомеханическая модель массива, находящегося в условиях запредельного деформирования, характеризующаяся постепенным хрупким разрушением пород и последующими взаимными перемещениями структурных блоков на глубинах свыше 500–600 м. Результаты. Расчетным методом определены радиусы зон деформирования массива, формирующихся в различных условиях вокруг капитальных выработок для всего диапазона проектных глубин исследуемого месторождения. Выявлен интервал оптимальных значений отпора и несущей способности крепи, обеспечивающих уменьшение радиусов зон деформирования вокруг горизонтальных протяженных и большеобъемных выработок дробильно-перепускных комплексов. Разработан технологический регламент проходки и крепления такого типа выработок, в котором учтены процессы запредельного деформирования породного массива, происходящие вокруг каждой из выработок. Выполнено обоснование типов (спецпрофиль СВП 17÷27) и параметров крепления параллельных взаимовлияющих выработок в условиях исследуемого массива, обеспечивающих требуемый отпор и устойчивость сближенных выработок, как в процессе проходки, так и при последующей эксплуатации. Апробация и практическая реализация полученных технологических решений в настоящее время осуществляется в процессе строительства околоствольных дворов новой очереди шахты ДНК Донского горно-обогатительного комбината.
СОВЕРШЕНСТВОВАНИЕ ПРОЦЕССА СОЛЯНОКИСЛОТНОЙ ОБРАБОТКИ СКВАЖИН ПРИМЕНЕНИЕМ НОВЕЙШИХ ТЕХНОЛОГИЙ И ОБОРУДОВАНИЯ
Authors: Хабибуллин Марат Яхиевич
Published: October 2020

Актуальность исследования обусловлена необходимостью обеспечивать равномерный нагрев раствора кислоты при скоростях закачки, создаваемых агрегатами, на термокислотные образцы. Решение этой проблемы позволит повысить эффективность кислотных и термокислотных обработок сильно дренированных скважин с низким пластовым давлением. Цель: разработать и предложить метод кислотного и термокислотного импульсирования, методику его применения и создать конструкции подземного и наземного оборудования скважин для осуществления разработанного метода. Объекты. Объем раствора, заливаемого в насосно-компрессорные трубы при термокислотной обработке методом импульсирования, зависит от их длины и внутреннего диаметра. Обычно он принимается равным 1,2–2 м3. Если в скважине, намеченной для проведения термокислотной обработки методом импульсирования, фильтр или его некоторая часть оказывались перекрытыми песчаной пробкой, то их предварительно очищали желонкой, не вскрывая зумпфа. А также используется специальный перфорированный наконечник и специальная заливочная головка. Методы. Термокислотную (как и кислотную) обработку скважины методом импульсирования проводят без применения насосного агрегата, что позволяет значительно сократить расходы. Ускорение движения кислотного раствора, нагрев всего объема до нужной температуры и создание давления (за счет веса столба раствора) способствуют увеличению глубины проникно­вения и эффективности воздействия кислоты на пласт. Результаты. Наиболее подходящим кислотным раствором для термокислотного импульсирования является 15 %-ная НСl, ингибированная униколом. Хорошие результаты дало внедрение способа кислотного импульсирования, предусматривающего использование специального наконечника, в котором канал штуцера полностью закрыт магниевым стержнем. В результате реакции магниевый стержень растворяется в кислотном растворе, после чего последний устремляется через освободившийся канал штуцера и перфорированный патрубок в фильтр, создавая так называемый кислотный импульс, т. е. достигается повышение скорости закачки под действием гидростатического давления.
УТОЧНЕНИЕ ГЕОЛОГО-ГИДРОДИНАМИЧЕСКОЙ МОДЕЛИ СЛОЖНОПОСТРОЕННОЙ ЗАЛЕЖИ НЕФТИ ПУТЕМ КОМПЛЕКСНОГО АНАЛИЗА ДАННЫХ
Authors: Козырев Никита Дмитриевич , Кочнев Александр Александрович , Менгалиев Александр Генрихович , Путилов Иван Сергеевич , Кривощеков Сергей Николаевич
Published: October 2020

Актуальность исследования обусловлена повсеместным использованием геолого-гидродинамического моделирования для процесса проектирования разработки нефтяных и газовых месторождений. При использовании стандартного подхода создания геолого-гидродинамической модели вероятен недоучет сложности строения и неоднородности свойств коллектора, что может оказать негативное влияние на прогнозные технологические и экономические показатели разработки месторождения. Цель: разработка методического подхода комплексного анализа и учета имеющейся разномасштабной промысловой и лабораторной информации при создании куба абсолютной проницаемости приоритетного месторождения. Объект: сложнопостроенная карбонатная залежь нефти Восточно-Ламбейшорского месторождения. Методы: оценка охвата исследованиями скважин; статистическая обработка данных исследований стандартных и полноразмерных образцов керна; переинтерпретация и комплексирование промыслово-геофизических и гидродинамических исследований скважин; создание и использование макросов в среде Visual Basic для автоматизации итерационных процессов сортировки, анализа данных и создания каротажной кривой абсолютной проницаемости; стохастическая интерполяция полученных данных с учетом сейсмической информации в геологическом симуляторе IRAP RMS (ROXAR); создание и использование фильтрационной модели в гидродинамическом симуляторе Tempest More (ROXAR). Результаты. Дана характеристика пластов рассматриваемой залежи нефти, особенности геологического строения; разработан методический подход по построению и уточнению куба абсолютной проницаемости в геолого-гидродинамической модели, обеспечивающий снижение степени неопределенности свойств продуктивного пласта; проведена сравнительная характеристика двух фильтрационных моделей, созданных на основе стандартного способа учета абсолютной проницаемости и согласно предлагаемой методики; отмечена более высокая степень сходимости расчетных и фактических технологических показателей разработки при использовании разработанного методического подхода уточнения абсолютной проницаемости продуктивного пласта; с целью оценки прогнозной способности геолого-гидродинамической модели пласта использован метод ретроспективного прогноза технологических показателей разработки пласта, отмечена удовлетворительная сходимость.
The value and use of project-based learning in teacher preparation programs
Authors: Alrajeh Tahani Salman
Published: October 2020

The study investigated faculty’s value and use of project-based learning (PBL) in preparing student teachers. A convergent mixed methods design was employed in collecting data. Although the participants addressed the need to support the PBL environment and highly reported the use of PBL in their current teaching practices, the ways they explained how to implement PBL do not reflect PBL in real applications. Participants thought that the other types of learner-centered approaches, such as problem-based learning, are the same as PBL, which led to a strong positive correlation between the value and use of PBL. Professional development sessions for faculty members, partnerships with local and international organizations, and continuous evaluation were found helpful in achieving successful implementation of PBL in teacher preparation programs.

Keywords: Teacher education, Project-Based Learning, Student teachers’ preparation programs
The effect of hot seat strategy on the 1st intermediate students' Reading comprehension
Authors: Abid Salih Omar
Published: October 2020

This study aims to investigate the effect of hot seat (HS) on the reading comprehension (RC) of 1st intermediate students during the academic year 2019-2020. To achieve the purpose of the study, it is hypothesized that there is no difference between the students' mean of the experimental group which is exposed to HS and that of control group which is not exposed to HS. The experiment has lasted for three weeks and the researcher has taught the two groups by himself. The researcher has used experimental design and chosen randomly a sample consisted of (63) students distributed into two groups. The experimental group as well as the control group are given a pre-test before beginning the experiment to measure the students' RC. The same test is given again at the end of the experiment in order to check whether the students' have been improved or not. The data has been collected and analyzed by using t-test for two independent samples. The results have showed that there was significant improvement in favour of the experimental group. Finally, some points can be concluded such as the importance of HS in teaching EFL because it increases students’ motivation and makes the lesson more enjoyable and effective. In the light of the findings, some recommendations were put forward. 

 

Keywords: Hot Seat, 1st intermediate Students, Reading Comprehension, EFL
Educational research productivity road map: Conclusions from the identified research barriers and variables
Authors: Suson Roberto , Capuno Reylan , Manalastas Rebecca , Malabago Nolasco , Aranas Amelia Girly , Ermac Eugenio , Tenerife Janine Joy
Published: October 2020

Research has been a buzz word in Philippine education, especially in HEI’s. This study was conducted to determine the barriers that undermined the research activities of the post-graduate students. A total number of 136 students were selected as respondents. The instruments used in this study consisted of a set of questionnaires containing 36 question items in perceived research barriers using 5 point likert scales and checklists for demographic profiles. The reliability value (Cronbach’s alpha) instrument for all variables obtained an alpha value exceeding 0.60. The results of the study were analyzed using descriptive statistics that derived means, standard deviations and correlation coefficient. Findings reveal that respondents have poor performance in research and publication. This could be attributed to the following aspects; the respondents were not fully equipped with skills on how to do research, lack of time in doing research due to heavy teaching workload, and limited financial resources. Lack of peer support and research experts contributes to the overall research barriers. The results reflect critical attention from the university. Thus, training, workshops and mentoring should be considered a priority for promoting and elevating the research productivity of the respondents. Meanwhile, financial supports from the university could also help overcome the barriers such as lack of incentives and article processing charge.
Keywords: Research productivity, research barriers, skills development, financial supports
Working with problem methods – possibilities for pupils and teachers
Authors: Kožuh Anna , Maksimović Jelena , Stošić Lazar
Published: October 2020

Development of self-assurance, improvement of interpersonal communication, development of the sense of security, an opportunity to share one’s experiences and ideas, as well as cooperation and interaction, which supplant rivalry and competition are just a few benefits resulting from working with the problem methods for the pupils. We have discussed the issue of benefits for both pupils and teachers resulting from working with the problem methods and the diagnosis of skills of the teachers of early education in the field of applying problem methods in their work with the pupils. The basic method applied during the study was diagnostic survey. The main technique of collecting data was the questionnaire survey, which was used to collect opinions of teachers from selected schools in Poland. In the second part of the analysis of research we present the profits for teachers working with problem methods. Remarks provided by teacher-respondents reveal very conscious attitude of the teachers, who understand the principles of permanent education and challenges they have to face in their work. The questionnaire of the survey was drawn up specifically for the conducted study.
Key words: teacher’s didactic workshop, theory and practice, teaching strategy, didactic competence
The phenomenon of "digital" death: formation and genesis of the attitude to death in social networks of students
Authors: Nikishina Vera B. , Sokolskaya Marina V. , Musatova Oksana A. , Loskutova Irina M. , Zapesotskaya Irina , Bogomolova Oksana
Published: October 2020

In this paper, we study the phenomenon of “digital” death, its genesis and the attitudes towards death in the context of social networks of students. As a result of the investigation we have discovered different forms of “digital death and the ways students react to it in social networks. We further investigate the origins of different user attitudes towards “digital death” and the impact of manipulative relation to death in social networks on the social reality. Some students stage their own death on social networks by posting images on their homepage, which has the intentions (i) to attract public attention, (ii) to express their auto aggression (iii) to make fun of death and (iv) to reduce their own anxiety of death by "sharing" the fear with other students. Our analysis shows that the main purpose of staging one’s death on social networks is to reduce the fear of death by creating plans, playing.
Keywords: Students, cyberspace, social networks, death, "digital" death, attitude to the death in the social networks.
The effect of self- questioning strategy in developing independent thinking in teaching physics
Authors: Al-Swelmyeen Monther Bsharh , Sakarneh Mohammad Abed , Al zabenc Ghadeer Pernec
Published: October 2020

This study aimed at determining the effectiveness of self- questioning strategy in developing independent thinking in teaching physics. The researcher used the Independent Thinking Test on a purposive sample consisted of (46) students from the first secondary scientific class in Amman schools in Jordan. A quasi-experimental approach was adopted. To analyze the data a statistical Package for the Social Sciences (SPSS) was used. The study showed a statistically significant difference between the means of the two groups (experiment and control group) in the independent thinking level and it was in favor of the experimental group. The study recommended preparing and developing teaching programs according to the self-questioning strategy and conducting similar studies on new samples at different age levels and new variables.

 

Keywords: Self-Questioning, independent Thinking, Physics.
Stress coping strategies of university students
Authors: Hatunoglu Bedri Yavuz
Published: October 2020

The purpose of this study is to examine university students' strategies for coping with stress in terms of various variables. The study was carried out with 215 girls, 86 boys and 301 people studying at Ağrı İbrahim Çeçen University in the 2019-2020 academic year. According to the research findings; It was found that students resort to social support, which does not show a desperate approach to the events in which they are more optimistic and confident in their strategies to deal with stress. It has been observed that students have positive behaviors in their strategies to cope with stress, their irrational beliefs and personal control of university students and their thoughts about being externally supervised, and especially believing in luck and striving, are related to their styles of coping with stress. Opinions differed between university students' genders and the faculty variables they studied.

Keywords: Stress, Stress Coping, Stress Coping Strategy, University students,
Upaya Meningkatkan Kemampuan Penalaran Matematis Siswa melalui Model Pembelajaran Treffinger pada Materi SPLDV di Kelas VIII-1 SMPN 3 Tangerang Selatan
Authors: El Hakim Lukman , Pinta Deniyanti Sampoerno
Published: October 2020

Abstrak

Penelitian ini merupakan penelitian tindakan kelas (PTK) yang bertujuan untuk meningkatkan kemampuan penalaran matematis siswa melalui model pembelajaran Treffinger di kelas VIII-1      SMPN 3 Tangerang Selatan. Subjek dalam penelitian ini adalah kelas VIII-1 yang terdiri atas 38 siswa dengan 16 siswa laki-laki dan 22 siswa perempuan. Fokus pengamatan pada dua siswa masing-masing pada kelompok atas, sedang, dan rendah pada materi pembelajaran Sistem Persamaan Linier Dua Variabel (SPLDV). Penelitian ini dilaksanakan dalam 3 siklus. Setiap siklus meliputi tahapan perencanaan, pelaksanaan, analisis, dan refleksi. Untuk memeroleh data kemampuan penalaran matematis siswa menggunakan tes kemampuan penalaran matematis. Hasil perolehan nilai untuk setiap subjek penelitian pada siklus I, yaitu SP1 mendapatkan nilai 62,5, SP2 mendapatkan 70,8, SP3 mendapatkan 45,8, SP4 mendapatkan 58,3, SP5 mendapatkan 37,5, dan SP6 mendapatkan 37,5. Pada siklus II nilai tiap SP meningkat, SP1 mendapatkan nilai 75, SP2 mendapatkan 75, SP3 mendapatkan 79,2, SP4 mendapatkan 62,5, SP5 mendapatkan 62,5, dan SP6 mendapatkan 50. Pada siklus III nilai tiap SP juga meningkat, SP1 mendapatkan nilai 79,2, SP2 mendapatkan 79,2, SP3 mendapatkan 83,3, SP4 mendapatkan 75, SP5 mendapatkan 75, dan SP6 mendapatkan 70,8. Ketuntasan klasikal subjek penelitian untuk kemampuan penalaran matematis dalam kategori baik pada  siklus III telah mencapai 83,33%, sehingga dapat disimpulkan bahwa penerapan model pembelajaran Treffinger dapat meningkatkan kemampuan penalaran matematis siswa kelas VIII-1 SMPN 3 Tangerang Selatan pada materi Sistem Persamaan Linier Dua Variabel.
Persepsi Peserta PPG dalam Jabatan terhadap Pelaksanaan Program PPG Hybrid Learning Bidang Studi Matematika Universitas Negeri Jakarta Tahun 2019
Authors: Tri Murdiyanto
Published: October 2020

Pendidikan dan Latihan Profesi Guru (PLPG) mulai tahun 2018 sudah tidak dilaksanakan dengan alasan kurang adanya relevansi terhadap peningkatan profesionalitas guru. Pendidikan Profesi Guru (PPG) dirancang untuk menggantikan PLPG yang mulai dilaksanakan tahun 2016 yaitu PPG SM3T (Sarjana Mendidik di Daerah Terdepan, Terluar, dan Tertinggal) dimana pesertanya adalah para guru yang sudah melaksanakan tugas mengabdi di daerah 3T. Tahun 2018 dilaksanakan PPG Prajabatan bersubsidi dan tahun 2019 mulai dilaksanakan PPG dalam Jabatan. PPG SM3T dan Prajabatan bersubsidi dilaksanakan secara tatap muka tetapi PPG dalam jabatan dilaksanakan menggunakan sistem Hybrid learning yang perupakan gabungan dari system daring dan sistem tatap muka dengan pertimbangan bahwa pesertanya adalah guru yang juga mempunyai tugas di sekolah sehingga tidak dapat terlalu lama meninggalkan tugas. Masalah yang muncul adalah apakah sistem PPG ini cocok untuk kondisi di Indonesia yang merupakan negara kepulauan dimana fasilitas pembelajarannya belum bisa merata dan apakah para guru siap untuk belajar secara daring. Tujuan penelitian ini adalah untuk mendapatkan masukan dari peserta PPG dalam jabatan terhadap pelaksanaan PPG Hybrid Learning bidang studi matematika Universitas Negeri Jakarta tahun 2019. Metode penelitian yang digunakan adalah metode deskriptif, fokus penelitian pada persepsi peserta PPG terhadap pelaksanaan program PPG dalam jabatan Hybrid Learning. Persepsi peserta PPG yang diukur terdiri dari dua bagian yaitu 1) penerimaan atau penyerapan dan 2) evaluasi terhadap proses yang dijalani selama program dilaksanakan. Subyek penelitian ini adalah peserta PPG dalam jabatan bidang studi matematika FMIPA UNJ tahun 2019 tahap 1 sampai tahap 4 tahun 2019. Teknik pengumpulan data dengan menyebarkan angket kepada responden. Angket yang digunakan berupa gabungan angket tertutup dan terbuka yaitu tertutup dalam bentuk pernyataan yang pilihan jawabannya sudah disediakan sedangkan terbuka untuk mendapatkan masukan mengembangkan proses pelaksanaan program PPG bidang studi matematika FMIPA UNJ. Hasil penelitian menunjukkan penerimaan atau penyerapan pada saat daring: kemudahan memperoleh sinyal internet, kemudahan menjalankan aplikasi, memahami capaian pembelajaran PPG, ketersediaan sumber belajar, kemampuan menyelesaikan tugas dan evaluasi persentase yang menyatakan setuju dan sangat setuju lebih dari 80% namun yang tertarik/tertantang dengan pembelajaran daring hanya 40 % dan yang merasakan beban sangat berat dalam pelaksanaan pembelajaran daring sebesar 75%. Evaluasi proses yang menyangkut kesesuaian materi dan capaian pembelejaran, kesesuaian tugas dan evaluasi dengan materi, kemampuan dan kinerja instruktur, pelayanan administrasi, fasilitas yang memadahi, kemudahan pelaksanaan PPL dan kecukupan durasi waktu PPL persentase setuju dan sangat setuju diatas 75 %. Tetapi untuk kecukupan durasi waktu daring dan porsi materi hanya 55% yang setuju dan sangat setuju.
Апротинин — новый препарат-кандидат для профилактики SARS-CoV-2 (COVID-19)
Authors: Иващенко Андрей , Свистунов Андрей , Хоробрых Татьяна , Логинов Владимир , Карапетян Рубен , Мищенко Наталья , Поярков Станислав , Волгин Максим , Якубова Елена , Топр Михаил , Пьянков Олег , Магеррамова Анастасия , Томилов Алексей , Иващенко Александр
Published: October 2020

Эффективность Апротинина в качестве профилактического лечения COVID-19 изучалась на экспериментальной модели SARS-CoV-2 у хомяков и у медицинского персонала, работающего с пациентами COVID-19 в стационаре. Показана высокая эффективность Апротинина в пред- и постконтактной профилактике SARS-CoV-2.
Estimates of Direct and Indirect Costs of Ankle Fractures
Authors: Noback Peter C. , Freibott Christina E. , Dougherty Tess , Swart Eric F. , Rosenwasser Melvin P. , Vosseller J. Turner
Published: October 2020

Background:

The quantification of the costs of ankle fractures and their associated treatments has garnered increased attention in orthopaedics through cost-effectiveness analysis. The purpose of this study was to prospectively assess the direct and indirect costs of ankle fractures in operatively and nonoperatively treated patients.

Methods:

A prospective, observational, single-center study was performed. Adult patients presenting for an initial consult for an ankle fracture were enrolled and were followed until recurring indirect costs amounted to zero. Patients completed a cost form at every visit that assessed time away from work and the money spent in the last week on transportation, household chores, and self-care due to an ankle fracture. Direct cost data were obtained directly from the hospital billing department.

Results:

Sixty patients were included in this study. With regard to patient characteristics, the mean patient age was 46.5 years, 55% of patients were female, 10% of patients had diabetes, and 17% of patients were active smokers. Weber A fractures composed 12% of fractures, Weber B fractures composed 72% of fractures, and Weber C fractures composed 18% of fractures. Operatively treated patients (n = 37) had significantly higher total costs and direct costs compared with nonoperatively treated patients (p < 0.01). In all patients, losses from missed work accounted for the largest portion of total and indirect costs, with a mean percentage of 35.8% of the total cost. The mean period preceding return to work of the 39 employed patients was 11.2 weeks. Longer periods of return to work were significantly associated with surgical fixation and having less than a college-level education (p < 0.05). The mean time for recurring observed costs to cease was 19.1 weeks.

Conclusions:

In patients treated operatively and nonoperatively, the largest discrete cost component was a specific indirect cost. Indirect costs accounted for a mean of 41.3% of the total cost. Although the majority of the direct costs of ankle fractures are accrued in the period immediately following the injury, indirect cost components will regularly be incurred for nearly 5 months and often longer. To capture the full economic impact of these injuries, future research should include detailed reporting on an intervention’s impact on the indirect costs of ankle fractures.

Level of Evidence:

Economic Level III. See Instructions for Authors for a complete description of levels of evidence.
A protocol for ethanol or isopropanol dosage in hand rub gels
Authors: Akhdar Ayman , Hersant Yael , Gautier Arnaud
Published: October 2020

A method of determination of the ethanol or isopropanol content in hydro-alcoholics hand rub solutions is reported. Based on quantitative 1HNMR (q1HNMR), the results are obtained rapidly and accurately. The method is available for viscous solutions to which other simpler techniques do not apply.
Knowledge of dentists, dental auxiliaries, and students regarding the COVID-19 pandemic in Saudi Arabia: A Cross-Sectional Survey
Authors: Shahin Suliman , Bugshan Amr , Almulhim Khalid , AlSharief Mishali , Al-Dulaijan Yousif , al-Qarni Faisal
Published: October 2020

Background: This study aimed to assess the knowledge and attitude of dental professionals in Saudi Arabia regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19).Methods: A questionnaire was developed to assess various dental professionals from both governmental and private sectors through online and social media outlets. Results: A total of 1,033 responses were collected (273 dental students, 193 dental auxiliary personnel, 544 dentists). Moreover, 63.4% of respondents (63.4%) were working in hospitals. Of all respondents, 44.9%, 33.4%, and 21.7% were in governmental clinics, academia, and private sector, respectively. Overall knowledge on incubation period and route of transmission of SARS-CoV-2 was consistent across all dental professions. Hand-soap cleaning time was statistically different among dental professionals (p < 0.001). The dental professionals displayed significant disagreement on the survival of SARS-CoV-2 outside the host (p < 0.001). Furthermore, 75.1% of respondents were reluctant to treat a suspected COVID-19 patient, and 92% participants believed that the mode of transmission was droplet inhalation. Fever, coughing, and shortness of breath were identified as the most common symptoms of COVID-19. Most standard methods of prevention in the dental office were selected by at least 50% of participants.Conclusions: Dental professionals on SARS-CoV-2 and COVID-19 seems to be consistent when evaluating the virus incubation period. However, virus survivability and recommended hand soap washing time was significantly variable among the professionals. A high degree of apprehension toward suspected COVID-19 patients existed among all dental professionals. Pandemic-awareness campaigns are essential among healthcare providers.
The protective impact of education on brain structure and function in Alzheimer’s Disease
Authors: Zhu Wanqiu , Li Xiaoshu , Li Xiaohu , Wang Haibao , Li Meiqin , Gao Ziwen , Wu Xingqi , Tian Yanghua , Zhou Shanshan , Wang Kai , Yu Yongqiang
Published: October 2020

Background: The Cognitive Reserve (CR) theory posits that brains with higher reserve can cope with more cerebral damage to minimize clinical manifestations. The aim of this study was to examine the effect of education (CR proxy) on brain structure and function in Alzheimer’s disease (AD) and amnestic mild cognitive impairment (aMCI) patients and in cognitively healthy elderly (HC) individuals.Methods: Fifty-seven AD patients, 57 aMCI patients and 48 HCs were included to investigate the relationships between education years and gray matter volume (GMV), regional homogeneity (ReHo) and functional connectivity (FC) in brain regions to show associations with both structure and function. Taking the severity of the disease into account, we further assessed the relationships in AD stratified analyses.Results: In AD group, the GMV of the dorsal anterior cingulate cortex (dACC) and ReHo in the left inferior temporal cortex (ITC) were inversely associated with education years, after adjustment for age, sex, Mini-Mental State Examination (MMSE), and total intracranial volume or head motion parameters. Seed-based FC analyses revealed that education years were negatively correlated with the FC between the left anterior ITC and left mid frontal cortex as well as right superior frontal cortex and right angular gyrus. Stratified analyses results indicated that this negative relation between education and GMV, ReHo, FC was mainly present in mild AD, which was attenuated in moderate AD and aMCI groups.Conclusions: Our results support the CR theory, and suggest that CR may be protective against AD related brain pathology at the early stage of clinical dementia. These findings could provide the locus of CR-related functional brain mechanisms and a specific time-window for therapeutic interventions to help AD patients to cope better with the brain pathological damage by increasing CR.
Spatiotemporal expression of regulatory kinases directs the transition from mitotic growth to cellular morphogenesis
Authors: Yang Shuo , McAdow Jennifer , Du Yingqiu , Trigg Jennifer , Taghert Paul , Johnson Aaron
Published: October 2020

Embryogenesis depends on a tightly regulated balance between mitotic growth, differentiation, and morphogenesis. Understanding how the embryo uses a relatively small number of proteins to transition between growth and morphogenesis is a central question of developmental biology, but the mechanisms controlling mitosis and differentiation are considered to be fundamentally distinct. Here we show the mitotic kinase Polo, which regulates all steps of mitosis from mitotic entry to cytokinesis, also directs cellular morphogenesis after cell cycle exit. In mitotic cells, Aurora B (AurB) activates Polo to control a cytoskeletal regulatory module that directs cytokinesis. In the post-mitotic mesoderm of late stage embryos, the control of Polo activation transitions to the uncharacterized kinase Back Seat Driver (Bsd), where Bsd activates Polo to direct muscle morphogenesis. The transition between mitotic growth and morphogenesis is accomplished through the spatiotemporal transcriptional regulation of AurB and Bsd. The functions of Bsd and Polo are conserved, arguing that regulating kinase expression to activate cytoskeletal regulatory modules is a widely used strategy to direct cellular morphogenesis.
COVID-19 Associated Acute Necrotizing Encephalopathy in a Hospitalized Cohort in Oregon
Authors: Vanni Holly , Jou Austin D , Choo Christine E , Walter Eric C. , Mularksi Richard A.
Published: October 2020

Background/Objective: Severe Acute Respiratory Syndrome Coronavirus-2 (SARSCoV-2) is a novel coronavirus strain that most commonly affects the respiratory system with observational studies and case reports suggesting this virus may target the central nervous system. To date there has been one case report of COVID-19 related acute necrotizing encephalopathy.Methods: Observational study of COVID-19 patients admitted to two hospitals of a large metropolitan health maintenance organization serving over 600,000 members using retrospective electronic and radiographic medical record evaluation across 4 months (March – June of 2020) after multiple cases of acute necrotizing encephalopathy were diagnosed.Results: During this time frame 216 patients were diagnosed with COVID-19, 106 (49%) required hospitalization, 21 (20%) required admission to the intensive care unit (ICU) and 18 (17%) required intubation. Of the 18, 4 (22%) had clinicoradiologic evidence of acute necrotizing encephalopathy (ANE) diagnosed, two with associated areas of hemorrhage.Conclusions: Acute necrotizing encephalopathy (ANE) with or without hemorrhage, is a rare CNS disease, usually seen in childhood as a complication of viral infections. We identified a high percentage of COVID-19 patients with clinicoradiologic evidence of acute necrotizing encephalopathy in our cohort. To our knowledge, ANE has not been reported in patients with SARS or MERS. Understanding the pathogenesis, neurotropism and effects of the SARS-CoV-2 virus is important in developing treatments and improving morbidity and mortality.
Prediction of COVID-19 prognosis by heterogeneity analysis based on chest CT scans
Authors: Yang Bo , Zhang Bei , Zou Jiani , Gao Lichen , Zhang Jian , Qiu Huaiming , Huang Wencai
Published: October 2020

This study aimed to estimate clinical outcome in individual COVID-19 patient by using histogram heterogeneity analysis based on CT opacities. 57 COVID-19 cases’ medical records were retrospectively reviewed from a designated hospital in Wuhan, China. Two characteristic lung abnormity opacities, ground-glass opacity (GGO) and consolidation opacity (CLO) were drawn on CT images to identify the heterogeneity by using quantitative histogram analysis. The parameters (mean, mode, kurtosis, skewness) derived from histograms evaluate the accuracy of clinical classification and outcome prediction. Nomograms were built to predict the risk of death and median length of hospital stays (LOS), respectively. The most highly frequency of lung abnormalities was GGO mixed with CLO in both survival population (26 in 42, 61.9%) and died population (10 in 15, 66.7%). The best performance heterogeneity parameters to discriminate severe type from mild/moderate counterparts were as following: GGO_skewness: specificity=66.67%, sensitivity=78.12%, AUC=0.706; CLO_mean: specificity=70.00%, sensitivity=76.92%, AUC=0.746. Nomogram based on histogram parameters can predict the individual risk of death and the prolonged median LOS of COVID-19 patients. C-indexes were 0.763 and 0.888 for risk of death and prolonged median LOS, respectively. The histogram analysis method based on GGO and CLO has the ability for individual risk prediction in COVID-19 patients.
Characterization of Bovine Neutrophil Extracellular Traps Induced by Histamine
Authors: Zhou Ershun , Wu Zhikai , Zhu Xingyi , Li Peixuan , Wang Jingjing , Yang Zhengtao
Published: October 2020

BackgroundHistamine plays an central role in many allergic diseases including allergic asthma and allergic rhinitis, and is also involved in bovine laminitis through regulating immune responses. Neutrophil extracellular traps (NETs) formation is a novel effector mechanism of neutrophils to defend against various stimuli. In the present study, we aimed to investigate the role of histamine on bovine NET formation and examined its fundamental molecular mechanisms. ResultsFirstly, the effects of histamine on neutrophil viability was measured by Cell Counting Kit-8 (CCK-8) and Lactate dehydrogenase (LDH) assays. The results showed that histamine had no significant influence on neutrophil viability. Then we characterized histamine-triggered NET formation by confocal microscopy and PicoGreen-derived NETs quantification. Confocal microscopy analyses illustrated NET structures by co-localizing the main components of NETs, and NET quantification revealed that histamine-triggered NETs were released in a dose-dependent manner. In addition, we found reactive oxygen species (ROS) production, phosphorylated extracellular signal-regulated kinase (ERK) and p38 proteins were significantly elevated in histamine-challenged neutrophils. By applying functional inhibitors of nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase), ERK and p38, histamine-triggered NETs were markedly reduced, indicating their importance in histamine-triggered NET formation. ConclusionsOur findings described histamine-triggered NET formation, and revealed its potential molecular mechanisms via NADPH oxidase, ERK and p38 pathways. This is the first study to depict NET formation induced by histamine, which could provide a new insight into histamine-related diseases.
Malaria Risk and Vulnerability of Communities Due to Climate Change in India
Authors: Hussain Syed Shah Areeb , Singh Poonam , Dhiman Ramesh C
Published: October 2020

Background: Malaria is an erstwhile public health problem that is further compounded in India due to diverse climatic conditions, ecology, socio-developmental indicators and the imminent threat of climate change. Mapping of malaria risk using climatic and ecological factors has been assessed to some extent but the vulnerability by taking into consideration the human factors i.e. socio-economics and adaptive capacity, in climatically vulnerable areas is not known. The present communication deals with determining the risk and vulnerability at district level by taking into account the hazard due to climate change, population exposed, ecological sensitivity and the community’s adaptive capacity.Methods: Based on the IPCC framework, relevant indicators for the dimensions of risk (Hazard, Exposure, Sensitivity, Adaptive Capacity) were identified from literature and was used to develop indices. Data for each indicator was obtained through government websites. Weights for different indicators were assigned using principle component analysis and the indices were aggregated to develop a district wise risk and vulnerability profile of India.Results: Malaria risk was found to be highest in Bihar (Ri=0.7) due to very low adaptive capacity coupled with high sensitivity. In some states with high climatic hazard and/or sensitivity for malaria, such as Tripura, Mizoram, Kerala and Tamil Nadu, high Adaptive capacity acted as a buffer, reducing the overall risk of malaria. Further, malaria risk is projected to be introduced for the first time in some districts of Himachal Pradesh and Arunachal Pradesh by 2030s due to the effects of climate change. Conclusion: The results of the study highlight the importance of various socio-development indicators in representing a holistic view of malaria risk. Adaptive capacity emerged as an important index as it could help counter the effects of climate change on malaria by enabling the community to cope with the adverse effects.
Microwave Ablation Efficacy Evaluation of Bone Tissue Based on Near Infrared Spectrum
Authors: Liu Yangyang , Yu Zhou , Meng Lin , Qian Zhiyu , Li Weitao , Lu Shengfang , Chen Ye
Published: October 2020

Background:Microwave hyperthermic tumor ablation has played an important role in the treatment of bone tumors because of its obvious curative effect, less side effects and fewer complications. The real-time evaluation of the curative effect in microwave ablation of bone tumors is a research tissue. In this paper, it proposes to study the ablation effect of bone tissue by near-infrared spectroscopy and optical parameters. First, bone tissue heating experiment was used to verify the difference in bone tissue near-infrared spectrum before and after heating. Results: In bone tissue microwave ablation experiment, it studied the changes of tissue near-infrared spectrum and optical parameters (reduced scattering coefficient, slope factor, area factor) during specific microwave ablation conditions. It was found that some factors (area(500-550), slope(524-532) and slope(565-570)) changed significantly, correlated with microwave ablation time, which could be used as evaluation factors of microwave ablation. Conclusions: The results lay a foundation for the development of a new method for real-time evaluation of ablation efficacy.