bluuebunny/crossref_metadata_2025 huggingface dataset:
Medidas de Calidad de Vida en Personas con Afasia. Revisión Sistemática
Authors: Garrido del Águila Dunia , Niño Ana Lydia , Carballo Gloria
Published: July 2022

La afasia después de un daño cerebral y sus diferentes condiciones negativas derivadas, afectan a la calidad de vida (CdV) de la persona. El objetivo de este estudio es describir y analizar la literatura de los años comprendidos entre 2016 y 2020 para identificar y cuantificar aspectos relevantes de la CdV y su evaluación en personas con afasia (PWA). Para lo anterior, se consultaron tres bases de datos (PsycINFO, Medline y Psicodoc). Se incluyeron 38 estudios. Se codificaron y analizaron las características de los estudios y se evaluó la calidad de los trabajos siguiendo las pautas marcadas por la STROBE y la NIH. Los resultados muestran que la prueba de evaluación de CdV más utilizada fue la Stroke and Aphasia Quality of Life Scale-39 (SAQOL-39) (n= 19, 50.00%). En la mayoría de los estudios, independientemente de las pruebas de evaluación, las PWA presentan una baja CdV. Los estudios seleccionados presentan una calidad metodológica media-alta. Como conclusión cabe destacar que, además de limitar aspectos de la comunicación y el lenguaje, la afasia afecta negativamente a la CdV de forma global de la persona que la padece. El desarrollo de pruebas de evaluación de la CdV puede ayudar a los profesionales a planificar una intervención adecuada.
Desempeño fonético-acústico de vocales en hablantes del español chileno con enfermedad de Parkinson en estadios iniciales
Authors: Martínez-Cifuentes Renato , Soto-Barba Jaime
Published: July 2022

La articulación de los sonidos lingüísticos consonánticos y vocálicos se afecta en la enfermedad de Parkinson (EP). En el caso de las vocales, esta alteración se manifiesta acústicamente en la estructura formántica y en el área de espacio vocálico. Debido a que no se ha explorado esta temática en Chile, la investigación tuvo por objetivo contrastar el desempeño fonético-acústico de vocales entre hablantes del español chileno con EP inicial y sin la enfermedad. Se efectuó un estudio cuantitativo, cuasiexperimental y correlacional. 15 hablantes con EP (M=69.6 años, DE=7.46) y 15 sin EP (M=70.07 años, DE=7.75) leyeron 30 frases que contenían las cinco vocales del español de Chile. Se analizaron los centros de frecuencia (F1 y F2) y los anchos de banda (B1 y B2) de los formantes vocálicos, y cinco índices del área de espacio vocálico. Se evidenciaron diferencias en el B2 de /i/ y /u/ entre personas con y sin EP; en el F1 de /e/ y /u/, el F2 de /u/, el B1 de /e/ y el B2 de /o/ entre hombres con y sin EP; y en el B2 de /i/ entre mujeres con y sin EP (p<.05). De esta forma, se reporta el desempeño acústico de las vocales en hablantes del español chileno con enfermedad de Parkinson.
Modernidad y religión: Durkheim, Marx y Weber sobre la memoria del neoliberalismo
Authors: Del Pino Díaz David
Published: July 2022

Este ensayo muestra las semejanzas inconfesables entre el neoliberalismo y la religióna partir de las raíces religiosas de la modernidad. Decisivas en este sentido son las aseveraciones de los pensadores Durkheim, Marx y Weber acerca de las abstracciones religiosas clásicas y las necesarias determinaciones desde los hombres “modernos”. Para identificar estas raíces el texto emplea tanto las reflexiones de Nietzsche como de las aportaciones decisivas de Foucault y Bourdieu en sus diferentes composiciones intelectuales.
De la comunidad a lo común: desplazamientos teóricos, éticos y políticos
Authors: Alvaro Daniel
Published: July 2022

En este artículo interrogamos dos conceptos capitales de la filosofía y la teoría social actuales: la “comunidad” y “lo común”. Nuestra hipótesis de lectura es que después de medio siglo de vigencia el debate sobre la cuestión de la comunidad comenzó a ceder lugar de manera progresiva al debate acerca de lo común. Con el objetivo de explicar lo que interpretamos como un desplazamiento de carácter epistemológico, pero también ético y político, emprendemos un análisis sobre los usos, significados e implicaciones de ambos conceptos en un conjunto heterogéneo de discursos contemporáneos, de Jean-Luc Nancy y Roberto Esposito a Christian Laval y Pierre Dardot, pasando por Michael Hardt y Antonio Negri.
Estado, educación y ciudadanía en Argentina entre 1880 y 1910: Julio A. Roca y Carlos N. Vergara. Tensiones discursivas en torno a la sumisión o la libertad
Authors: Visaguirre Leonardo Javier
Published: July 2022

En este trabajo examinamos las concepciones de Estado y ciudadanía presentes en la tensión entre la oligarquía y el krausismo en la Argentina, a finales del siglo XIX y principios del siglo XX. Abordamos metodológicamente el tema desde una perspectiva que mixtura la genealogía con la historia de las ideas filosóficas. Visibilizamos las contradicciones que subyacen en la concepción de Estado de J. A. Roca, entre su discursividad iusnaturalista y liberal y sus prácticas gubernamentales iuspositivistas y autoritarias. En contraposición, explicitamos las críticas que C. N. Vergara realiza al accionar del Estado bajo la dominación oligárquica, desde un iusnaturalismo teológico krausista - una alternativa estatal democrática y armonicista -. Finalmente, rescatamos la propuesta superadora de Estado y ciudadanía que Vergara propone para potenciar la libertad y la organización del pueblo en pos de combatir el centralismo y la corrupción estatal del régimen oligárquico.
Neoliberalismo y extrema derecha. Una problematización desde Spinoza
Authors: Gómez Rincón José Francisco
Published: July 2022

Partiendo de una interpretación en clave política de la filosofía de Baruch Spinoza pretendemos mostrar cómo la ideología neoliberal y su particular modo de entender el mundo y cómo debe ser la relación entre los sujetos, es un ingrediente clave para que los partidos y movimientos de extrema derecha logren sus objetivos. El proyecto político neoliberal sería incompatible no solo con la democracia, sino que con la sociedad humana misma y en consecuencia la aplicación de las recetas neoliberales desde los años 80 sería la responsable de la actual crisis de las democracias occidentales que están dando lugar al crecimiento de las llamadas democracias iliberales que tanto preocupan a los teóricos de la política por cuanto suponen un gran paso atrás respecto a la conquista de derechos fundamentales y el mantenimiento de la paz social.
El Leviatán en la doctrina del Estado de Carl Schmitt. Entre la crítica y la tragedia.
Authors: Latorre Merino Jorge
Published: July 2022

En este artículo se presentará un recorrido por los aspectos cruciales que marcan la lectura del Leviatán ofrecida por Carl Schmitt, prestando especial atención a la muerte del Estado en el contexto de la Segunda Guerra Mundial. En un primer momento, mostraremos la crítica velada que Schmitt vierte contra el nazismo como responsable de la muerte de la estatalidad moderna. Más adelante, pasaremos a analizar las condiciones históricas que explican el surgimiento de esta forma política, así como las consecuencias teológicas de dicha aparición. Por último, ya en las conclusiones, trataremos de contribuir al estudio de la mirada que el jurista arroja para una época post-leviatánica. Este último punto puede servir como alternativa analítica para, en adelante, explorar las consecuencias de la muerte del Estado decretada por Schmitt, y no tanto sus causas.
Subjetividad conspirativa contemporánea. Notas para una cartografía teórica
Authors: Ureña Salcedo Jon
Published: July 2022

El artículo trata de acometer una aproximación intelectual al concepto de teoría conspirativa, a fin de explorar tentativamente posibles cartografías para una adecuada comprensión de su significatividad y pregnancia contemporáneas. Para ello, se procederá a un somero repaso de las aportaciones recientes al estudio de las teorías conspirativas desde una pluralidad de disciplinas (estudios culturales, teoría política, psicoanálisis, psicología social o filosofía) y a una exploración de sus mecanismos de funcionamiento y sus posibles funciones dentro del campo de fuerzas configurado alrededor de la relación existente entre neoliberalismo y populismo. Finalmente, se propone una concepción de la teoría conspirativa contemporánea como una forma de teodicea, en cuanto a que cumple funciones de explicación del mal y de desplazamiento de la responsabilidad.
Consideraciones en torno a la teoría crítica de Rahel Jaeggi
Authors: Florito Mutton Alan Matías
Published: July 2022

El objetivo de este trabajo es examinar el diagnóstico crítico que Rahel Jaeggi realiza de la sociedad. El trabajo comienza desarrollando el análisis que lleva a cabo de la crítica de la ideología. Luego mostraremos los elementos centrales de su teoría crítica desplegados en Alienación y Crítica de las formas de vida. La conclusión es que la teoría crítica de Jaeggi es una crítica inmanente y una crítica de la ideología de la sociedad contemporánea.
El molino del diablo. Tiempo y poder a partir de Pierre Bourdieu
Authors: Cristiano Javier Luis
Published: July 2022

El artículo se propone establecer, a partir de una lectura sistemática de la obra de Pierre Bourdieu, algunas relaciones conceptuales entre poder y constitución social del tiempo. Partiendo del supuesto de que el tiempo, el modo en que lo experimentamos, concebimos y empleamos, es una construcción social, se tratan de identificar algunas de las maneras en que el poder interviene en esos procesos de construcción, tarea para la cual la obra de Bourdieu es no sólo estratégica sino insoslayable, pues está entre las pocas que se han ocupado en profundidad de ambos temas.  El artículo identifica primero las coordenadas generales del tratamiento bourdiano de ambas cuestiones, diferenciando cinco dimensiones del tiempo social: la del tiempo como experiencia práctica, como recurso, como coacción estructural, como representación del pasado y del futuro y como tensión existencial. En cada una, luego, se elaboran relaciones concretas entre poder y tiempo, que se pasan en limpio globalmente en las conclusiones.
Okullarda Yaşanan Olası İş Kazalarının Maliyetleri ve Sonuçları
Authors: Aydemir Ayşe
Published: July 2022

The aim of this study is to contribute to the literature by determining the costs and consequences of possible occupational accidents in schools. Another purpose of the study is to focus on the consequences of occupational accidents by determining the amount of costs of occupational accidents based on research conducted on the subject. For this purpose, the conceptual framework of possible occupational accidents in schools was explained, the costs of occupational accidents that often occur in schools were determined and their consequences were focused on. Considering the extent of possible occupational accidents in schools, deaths, loss of limbs and work accidents resulting from injury, the pain experienced and all the damage suffered, it becomes clear to what extent the need to take appropriate and correct measures on the subject in order to prevent occupational accidents is essential. Key Words: School, Occupational Safety, Occupational Accidents
Eğitim Kurumlarında İş Sağlığı ve Güvenliği Yönetim Sistemlerinin İncelenmesi
Authors: Baykal Serhan , Sarı Faruk , Arslan Güllü
Published: July 2022

In this study, general information about occupational health and safety in educational institutions and related and related issues was given and an inclusive understanding of the issue was provided within this framework. The conceptual framework defined the concept of Occupational Health and safety in educational institutions, Occupational Safety and health between the parties, namely the importance and responsibilities between employers and workers and occupational health and safety are addressed with an emphasis on the administrative systems of all of these issues in its own right and needs to be done about these business processes have been classified and analysed. Our subject which forms the main theme of the administrative processes of educational institutions that are relevant to occupational health and safety element of the string administrative structure, plan activities, responsibilities and implementation, vetire the procedure, and the development of the political arena, improvement in the processes of success by providing the necessary resources in order to maintain accommodates review. Key Words: Educational Institutions, Occupational Health and Safety, Management Systems
Eğitim Kurumlarından Tekstil Meslek Liselerinde Yaşanan Meslek Hastalıklarının İncelenmesi
Authors: Denizci Ahmet Salih
Published: July 2022

Textile students from educational institutions working in vocational high schools exposed identification of occupational diseases and occupational diseases and occupational health and safety principles in order to avoid the occurrence of cases of violation of the measures that need to be taken in this study which examined textile training institutions in vocational schools, occupational accidents, occupational diseases and to examine the measures necessary to be taken for them. Nowadays, scientific studies and technical developments have brought new production methods and models with them. The production process, which has become more complicated with the methods developed in production and the tools being used, has caused students to suffer from occupational diseases with many work accidents. Key Words: Textile Vocational High Schools, Textile Sector, Occupational Diseases
Qualification of the real multiple offences
Authors:   Academy of Economic Studies of Moldova, Prisacari Vadim
Published: July 2022

In this scientific research is approached the real multiple offences, as well as its qualification rules. Its characteristic features are outlined. A distinction is made between the real multiple offences and some forms of the single offense. It is shown that in the case of the multiple offences with a etiological connection, the initial action (inaction) (committed in order to facilitate the commission of another offence) constitutes in itself a distinct offence, reason for which, in this situation we are in the presence of a multiple offences, but not of a complex offence. When qualifying a single (complex) offense, the rules of the multiple offences cannot be applied at the same time. The rules on multiple offences may be applied only if, in addition to the complex offense, an additional offense is committed.
Computer data administration in the criminal process
Authors:   Balti District Prosecutor's Office, Republic of Moldova, Covalciuc Ion
Published: July 2022

Although the importance of evidence in the investigation of crimes is a fact unanimously recognized, the way in which they come to produce effects in the criminal process differs not only from one historical period to another, from one system of law to another, but also within the same state, and sometimes also within the same period of time. Besides the informative elements on the basis of which the state authorities understand how to settle criminal law conflicts, no less important is the way in which they come to influence the decisions of the judicial bodies, to be administered in the criminal process. The way in which the legislator understands to regulate the procedure for the administration of evidence is fundamental not only for the resolution of the criminal process, but also last but not least for its fairness. The problem becomes more sensitive when scientific and technical progress calls for new approaches not only at the law enforcement level but also at the regulatory level.
The right to a healthy environment: the role of treaty-based supervisory mechanisms
Authors:   Moldova State University, Iordanov Iordanca-Rodica , Rosca Valentin ,   Moldova State University
Published: July 2022

A healthy environment is necessary for the full enjoyment of human rights. However, if we approach the field of human rights and its link with environmental protection, we have a unique „trident“ made up of its inseparable elements - human rights and fundamental freedoms, health and environmental protection. Considering the connection between human rights and environmental protection, we can unequivocally argue that the treaty-based supervisory mechanisms in the field of environmental protection are relevant to our study and their applicability to the human rights segment. An example in this chapter would be the international legal framework on environmental impact assessment (EIA) in transboundary areas. A remarkable success in codifying the institution of EIA in international law was the adoption of the Convention on Environmental Impact Assessment in Transboundary Areas (Espoo, 25 February 1991). In addition to the importance of the Espoo Convention for the protection of the environment, an „indirect” environmental protection mechanism is also emerging.
Assessing two strategies for production of murine ascites with anti-SARS-CoV-2 monoclonal antibodies
Authors: Pérez-Paz Joel Javier , Blanco Reinaldo , Dorta Dayamí , Domínguez Andy , Maylin Pérez-Bernal  , Tamayo Celia , Hernández Carlos , Pina Ricardo , Díaz Javier , Pérez Shaylí , Pasarón Ivis , Pérez Enrique
Published: July 2022

Studies were conducted to improve the production of murine ascites with monoclonal antibodies that recognize SARS-CoV-2 proteins. BALB/c mice were primed with 0.5 mL of mineral oil into the abdominal cavity. Seven days after priming, mice were divided in two groups: the group 1 was inoculated intraperitoneally with 2x106 cells/mL of MAb-secreting hybridomas against the nucleocapsid and spike proteins of SARS-CoV-2; the group 2 was injected simultaneously with the same inoculum of hybridoma cells and mineral oil, 18 days after priming. No disturbances or suffering signals were observed in mice from both groups, suggesting that double administration of mineral oil did not produce significant distress with respect to the single dose used for priming, and that none of the hybridoma cell lines were particularly aggressive for the inoculated mice. Ascites was collected in 90.48% and 97.68% of mice from groups 1 and 2, respectively. Ascites was not collected in 7.42% of all mice. The main cause was they never developed ascites tumors but no solid tumors were observed either. The volume of ascitic fluid per mouse was increased significantly in mice from group 2, and there were no significant differences between groups in terms of the concentration of IgG in clarified ascites. According to these results, to obtain higher amounts of MAb the strategy applied in group 2 should be used, since it showed the best results in the development of ascites tumors and it significantly increased the volume of ascites fluid per mouse. This could allow the use of fewer animals for ascites production, which is an ethical and economic benefit.
ETIOPATHOGENETIC MECHANISM IN DOG SYRINGOMYELIA
Authors: Lacatus Caroline-Maria
Published: July 2022

Syringomyelia (MS) is a condition characterized by the development of cavities in the parenchyma of the spinal cord (sirinx). Cavalier King Charles Spaniel (CKCS) dogs have a high incidence of Chiari malformation. The breed was born in 1928, from dogs of the King Charles Spaniel breed, a favorite dog of royal and noble families, with the aim of recreating a dog similar to the one present in the portraits of King Charles II, during the restoration period. The CKCS breed is native to the United Kingdom, being composed of small brachycephalic specimens - toy, a distinctive feature of the breed being the flattened and miniaturized appearance of the head (Rusbridge & Knowler, 2003).

Syringomyelia is a topical and real interest topic in canine neuropathology, representing the topic of numerous researches, both due to the many unknowns of the evolution of the diseases, and the fact that at present there is no effective treatment.
The use of Complementary medicine and Pneumo-Acupuncture to treat muscle atrophy and chronic respiratory disorders in a dog: A case report
Authors: Dragomir Madalina , Ardelean Alina , Nadal Lorena Lloret , Ober Ciprian
Published: July 2022

A 5-year-old female Malinois dog was referred to the Faculty of Veterinary Medicine of Cluj-Napoca for complementary medicine treatment. The patient was diagnosed with severe muscular atrophy in the temporal region but also with ab-ingestis pneumonia due to improper use of the masticatory muscles. After 2 months of symptomatic therapy, partial cure of pneumonia was achieved, but the patient was left with an acute cough during the night. We decided to start a therapeutic protocol combining various Chinese therapies including acupuncture, electroacupuncture, pneumo-acupuncture and herbal therapy. The patient’s condition improved considerably even after the first sessions, coughing episodes were reduced and breathing became normal. As for muscle atrophy, the results were partially improved. At the end of the treatment scheme, although the patient was not completely cured, the quality of life was significantly improved.
Reconstruction of Body Height Using Right Hand-Palm Length and Middle Finger Length among Sangli District Population
Authors: A. Mane Dr. Vaishali , Satpute Dr. Supriya , Mane , Dr. A. Y.
Published: July 2022

Estimation of stature is significant and unique feature in personal identification in events of natural disasters, murders, accidents. With increasing frequency of mass disasters like floods in Sangali district, therefore these methods will be more helpful and useful for identification of individual. To finds out the correlation between right hand – length of palm and middle finger with body height (stature). The cross sectional study was with 100 subjects in the age group of 18-20 years native of Sangali district. The study was conducted after taking institutional ethical clearance. This study shows the positive significant correlation is found between the right-hand palm lengths, right hand middle finger with body height. But the middle digit finger is strongly positive than palm length.

Keywords: Estimation of stature, Reconstruction of Body Height, Right Hand-Palm Length, Middle Finger Length, Sangli District.
The influence of controlled changing factors on the reproductive ability of the firstcalf cows of the sychevskaya breed
Authors: Prishchep E. A. , Leutina D. V. , Gerasimova A. S.
Published: July 2022

The reproductive capacity of livestock can be increased by breeding. The influence of controlled changing factors on the reproductive ability of the Cows of the first calving the Sychevskaya breed was studied, taking into account the inbreeding coefficient in order to improve the breeding process. In breeding work with animals, two methods of crossing are used: outbreeding and inbreeding. A measure of the genetic consequences of inbreeding is the inbreeding coefficient. The studied number of first-calf cows was grouped into groups according to the inbreeding coefficient. Calculated by the intergroups and intragroups differences, the strength of influence and reliability in the cows of first calving the method of variance analysis. The average age of the first calving in inbred cows was 30 months, overestimated in animals with a coefficient of 12.5 and higher. The effectiveness of the multiplicity of inseminations in groups by the first lactation is excellent (1.4-1.5) and good with close inbreeding (1.7). In first-born heifers with an inbreeding coefficient of 0.1-0.59%, the average duration of the period between the calvings is 10 and 9 days less than in animals with moderate, close and closely related breeding. The fertility index of the first heifers of the groups is average, except for animals with close inbreeding. The results of the analysis of variance in breeding work with factors are statistically significant, but have unequal alternative variability. For further breeding work, taking into account the reproductive ability of animals, it is necessary to conduct inbred selection in moderate degrees. It is also necessary to take into account the reliable influence of controlled factors: such as the age of the first calving, the multiplicity of insemination, the fertility index, which allow increasing the efficiency of selection work.
Dynamics of indicators of coagulation hemostasis of cows during different physiological periods under the conditions of extensive and intensive livestock management
Authors: Gnezdilova L. A. , Kruglova Y. S.
Published: July 2022

The article presents the results of a study of coagulation hemostasis in cows under conditions of intensive and extensive production in different physiological periods (dry, fresh and at the peak of lactation). Disorders of coagulation hemostasis have been revealed in productive animals in different physiological periods under both intensive and extensive housekeeping, and a relationship has been established with feeding, keeping and exploitation.It has been established that the index of activated partial thromboplastin time (APTT) is significantly higher in dry cows with both intensive and extensive management. Prolongation of prothrombin and thrombin time and a decrease in the amount of fibrinogen were noted, which indicates a deficiency of coagulation factors and indicates hypo- or dysfibrinogenemia. For the first time, a conclusion was made about the possibility of using indicators of coagulation hemostasis as an objective assessment of the influence of technological factors in conditions of intensification of production.
Determination of the concentration of selective progesterone receptor modulators in blood plasma BY LC–MS/MS
Authors: Nikolaev S. V.
Published: July 2022

High-performance liquid chromatography mass spectrometry is a hybrid method and combines independent processes of liquid chromatographic separation and mass spectrometric analysis, which makes it possible to effectively determine the concentration of various substances in complex substances. The optimal parameters for the determination of progesterone, 17-hydroxyprogesterone capronate (17-OHPC) and aglepriston in the blood plasma of cattle by this method have been established in the work. The quantitative determination of the components was carried out by the method of an external standard using reference substances and preliminary construction of calibration dependencies (absolute calibration). To account for the effect on the result of the analysis of various components of blood plasma, the matrix calibration method was used using "pure" plasma, i.e., it did not contain detectable compounds. It was experimentally determined that the time of progesterone peak release is within 2.72 minutes, and the optimal precursor ion is m/z =315.3. In the course of the work carried out, it was found that in the blood plasma of animals, endogenous progesterone is well detected by the developed method according to the parameters set for the synthetic analogue. The peak time of 17-OHPC occurred after 4.20 minutes, and the optimal precursor ion had a mass of 429.2 au. The first stage of studying the kinetics of 17-HPC in cattle showed that the steroid is well visualized on the chromatogram even in low concentrations. The outputs of the peaks of aglepriston were observed at 2.25 minutes, and the optimal precursor ion was equal to 432.2 au.m. The chromatogram even at low concentrations of the steroid had a low noise level, and the concentration of the steroid in the blood plasma a day after injection of 20 ml of 3% aglepriston solution to a lactating cow was 7.2 ng/ml. Thus, optimal parameters were selected for determining the concentration of selective progesterone receptor modulators in the blood plasma of cattle, which allows for further evaluation of the pharmacokinetic properties of these steroids after their use.
Pathogens of bovine mastitis and their sensitivity to antimicrobials
Authors: Balbutskaya A. A. , Skvortsov V. N.
Published: July 2022

Mastitis is the most important disease in the dairy industry. Antibiotics are considered to be the first choice in the treatment of the disease. However, the problem of antibiotic residue and antimicrobial resistance, leads to many restrictions on antibiotic therapy in the dairy sector worldwide.The work is devoted to the study and analysis of the sensitivity of pathogens of acute mastitis in cows to different antibacterial drugs. Bacteriological studies were carried out according to the generally accepted methods. Antibiotic sensitivity was determined by the disk diffusion method.The dynamics of isolation of the main pathogens of acute mastitis in cows and their antibiotic sensitivity within a 5-year period (2017-2021) in the central region of Russia was analyzed. It has been established that in recent years gram-positive infections became predominant, while coagulase-negative staphylococci are increasingly replacing S. aureus. Representatives of the genus Enterococcus were predominant causative agents of the disease. High-level multidrug resistance of all isolated strains of pathogens was determined (97%).The improvement of laboratory diagnosis and strict control over the use of antimicrobials need to reduce the level of resistance and the spread of multi-resistant pathogens of pyo-inflammatory diseases.
Laboratory testing of film-forming substances for the manufacture of ophthalmic medicinal films
Authors: Gorohova M. M. , Shulunova A. N. , Fedota N. V. , Kvochko A. N.
Published: July 2022

In the manufacture of ophthalmic medicinal films, special attention should be paid to the choice of a film-forming substance, since both the shape of the future film and its medicinal properties as a whole depend on it. This article provides a laboratory analysis with a comparative assessment of the optimal concentrations of two film-forming substances, polyvinyl alcohol and gelatin. Most of the presented film formers have a number of disadvantages, such as thickness, insufficient strength and elasticity, heterogeneity, formation of cracks and creases. One of the requirements for ophthalmic medicinal films is the smoothness of the surface and the absence of sharp corners. Based on the foregoing, we set the goal of the study - to conduct a laboratory test of film-forming substances for the manufacture of ophthalmic medicinal films. An analysis of domestic and foreign works gave reason to use polyvinyl alcohol and gelatin as the basis for ophthalmic medicinal films. As a result of the study, we have established the optimal concentrations of film-forming substances (polyvinyl alcohol and gelatin) that meet the existing requirements. The optimal concentration of the gelatin solution was the ratio of 1:7. The addition of the plasticizer glycerol to gelatinin the manufacture of ophthalmic medicinal films is mandatory. The optimal concentration of the solution of polyvinyl alcohol was the ratio of 1:15. Films from both film formers did not lose their shape, did not form cracks or breaks when introduced into the conjunctival sac. No irritant effect was observed. Laying the films did not cause difficulties. Forms of gelatin completely dissolved in the eye in 40 minutes, of polyvinyl alcohol - in 90 minutes.
Assessment of regeneration of the bronchial ciliated epithelium with an increase in vitamin A content in the diet turkey
Authors: Azhikina O. Yu. , Karpenko L. Yu. , Polistovskaya P. A.
Published: July 2022

The study was aimed at studying the relationship between the concentration of vitamin A in the turkey diet and the change in the amount of ciliated epithelium in the bronchi. Methods and methodology: to increase the dosage of vitamin A, the “Alphabet AD3E” multivitamin complex was used in the experimental group for 10 days with the slaughter of poultry on days 3, 5 and 10 of the study with the study of macro and microcartins of the epithelium with the counting of ciliated epithelium cells per 1000 cells in each bird. Subsequently, the concentration of cells of the ciliated epithelium was analyzed in the experimental and control groups. The results of the study demonstrated not only an increase in the number of cells of the ciliated epithelium in the experimental group compared to the control group by 27.3% at the end of the experiment, but also allowed us to note a greater speed of processes during the recovery period after the respiratory disease of the turkey. The scientific novelty lies in the study of the relationship between the concentration of vitamins in the diet of poultry and the quantitative change in the epithelium of the respiratory system of poultry, which in turn is necessary for a broader understanding of the causes and spread of diseases of the respiratory tract.
The rick factors of the occurrence and development of intranasal neoplasms in cats
Authors: Melikova Yu. , Sotnikova L. , Stekolnikov A.
Published: July 2022

Intranasal neoplasms in cats are less common than in dogs and, according to the literature, account for up to 1% of all neoplasms in cats. Most often, carcinoma and sarcoma develop in cats of the middle age group, and intranasal lymphomas are more common in younger animals.The etiological factors causing intranasal neoplasms in cats are diverse. The algorithm for diagnosing nasal neoplasms in cats depends on the clinical manifestations of the process and includes diagnostics aimed at determining the clinical stage of cancer and making a final diagnosis based on a morphological conclusion. And also a diagnostic algorithm is necessary for the choice of treatment methods. The determination of the clinical stage directly depends on the visualization of the neoplasm in the nasal passages, the involvement of one or two nasal passages in the oncological process, the degree of spread of the tumor into the surrounding tissues – using visual diagnostic methods such as MRI and CT aimed at determining the localization of pathology, the spread, the degree of invasion and the degree of involvement of blood vessels in a specific oncological process. Diagnostic methods such as palpation of regional lymph nodes, chest X-rays and ultrasonography of abdominal organs are aimed at determining the clinical stage of oncopathologies.
The Mediating Effects of Child Mastery Motivation on the Relationship Between Parenting and Children’s Readiness to Learn: A Structural Equation Analysis
Authors: METİNDOĞAN Ayşegül
Published: July 2022

The focus of the study was to explore how parenting and children’s motivation to learn would influence preschool children’s readiness to learn at school. Two-hundred-thirty-two mother-father dyads reported on their socioeconomic status (SES), child rearing practices and perceptions of their preschool age children’s mastery motivation (gross-motor persistence, object persistence, social symbolic persistence, and mastery pleasure). The preschool teachers reported on children’s readiness measured by five domains (physical well-being, emotional maturation, social competence, language and cognitive competence and communication and general knowledge) and children’s mastery motivation. Structural equation modeling (SEM) analyses revealed that mastery motivation in children was a significant and a positive predictor of children’s school readiness; and the effects of parenting was mediated by mastery motivation.
Pharmacognosy and Phytochemistry of Tinospora cordifolia
Authors: B. Satpute Pankaj , N. Vikhe Dattaprasad
Published: July 2022

Guduchi is a Sanskrit word that meaning "protector of the body." It's also known as amrta or nectar, and it's incredibly beneficial for boosting the body's immune system and balancing the activities of its numerous organs. As a result, attempts have been made in the current research activity to give a comprehensive study on Guduchi Satva, with its authentication and validation carried out in a variety of ways. Tinospora cordifolia Genuine and market samples were examined for pharmacognostic characterization, phytochemical screening, and antibacterial testing during standardization. According to studies, the market sample was tainted and could not be used as a safe and effective medicine. This identification was utilized to create multiple markers for guduchi satva standardization. These features can also be employed as key identifiers in Ayurvedic pharmacopoeia. As a result, these indicators may be employed scientifically to detect adulteration and maintain medicine purity. In this study, a single Guduchi formulation, Guduchi Satva, is prepared using three different sizes (diameters) of Guduchi stems in three different batches in order to determine the ideal size of Guduchi stem that should be used to obtain the highest yield. Throughout the investigation, standard surgical protocols are followed.
Applications of K-Theory in Materials Science
Authors: Prodan Emil
Published: July 2022

Heisenberg formulation of quantum mechanics puts a focus on the physical observables which are organized as operator algebras. This approach and point of view has recently penetrated into metamaterials science. The goal of this talk is to explain this statement and to demonstrate the power of the theoretical tools that comes from the field of operator algebras, such as K-theory. As we shall see, the dynamical matrices of various classes of metamaterials generate specific topological algebras that can be computed explicitly. This will be exemplified using the class of periodic metamaterials, then that of quasi-periodic metamaterials and, lastly, that of metamaterials symmetric to a full space group. The talk will then introduce the notions of complete topological invariants and of stable homotopy. The equivalence class of a band projection with respect to the stable homotopy defines the complete topological invariant that can be associated with that projection and these equivalence classes lead to the K-group of the algebra of dynamical matrices. The last part of the talk exemplifies the K-groups for classes of metamaterials mentioned above. As we shall see, once the K-groups and their generators are known, one can produce a complete list of topological models which supply all topological phases supported by a particular class of metamaterials. Additional ways of using the K-groups will be presented.
Proposals for the reform of EU fiscal rules
Authors:   Bank of Greece, Ventouris Nikos , Palaiodimos Georgios
Published: July 2022

The aim of this paper is to contribute to the ongoing debate regarding the reform of the EU fiscal framework, with a special focus on fiscal sustainability for Greece. Our key policy proposals for the EU fiscal rules draw on lessons from past experience, the conclusions of relevant studies and the fiscal sustainability risks faced by Greece and other high-debt countries in the euro area. To this end, we use the European Fiscal Board’s Compliance Tracker Dataset to assess compliance with the existing SGP framework. Moreover, we employ the Bank of Greece’s Debt Sustainability Analysis (DSA) model to identify possible fiscal sustainability risks for Greece over the medium- to long-term horizon, taking into account alternative economic policy scenarios (including a debt rule scenario). Our main findings indicate that the revised fiscal framework should focus on the need to enhance sustainability of public debt as a key priority, by setting a debt anchor as a medium-term fiscal objective, with a single operational expenditure rule that promotes countercyclicality of fiscal policy. The current benchmark levels could be maintained and complemented with the appropriate flexibility in the rate of debt reduction to address cross-country heterogeneity and avoid self-defeating effects of fiscal policy. In the case of Greece, despite the favourable characteristics of public debt, fiscal policy in the short and medium term should focus on accelerating debt reduction. The exposure of Greece’s public debt dynamics to market and interest rate risks will gradually increase, as official sector debt is replaced by market financing, thereby changing the structure of public debt and highlighting the need to create fiscal buffers in order to increase its resilience to future adverse macroeconomic shocks.
Metainvestigación en narrativas transmedia: aportes desde Iberoamérica
Authors: Piñeiro-Naval Valeriano , Crespo-Vila Raquel
Published: July 2022

La convergencia y la cultura participativa son dos de los fenómenos más característicos del actual ecosistema mediático. El principal punto de encuentro entre ambos descansa en las narrativas transmedia, relatos complejos que fluyen a través de múltiples medios y soportes y que cuentan, en última instancia, con la colaboración de las audiencias para su expansión. El presente estudio tiene por objetivo describir de qué modo se ha llevado a cabo la investigación iberoamericana de alto impacto en esta materia durante la última década (2011-2020). Para ello, se llevó a cabo una metainvestigación a partir de una muestra de 148 artículos cuyo mínimo común denominador era, precisamente, el concepto de transmedia. Tras un análisis de contenido sistemático, objetivo y cuantitativo, es posible afirmar que esta producción académica tiene un marcado carácter empírico y cualitativo y está habitualmente centrada en el estudio de los relatos de ficción que se divulgan mediante las industrias culturales tradicionales. No obstante, también se observa un cambio de tendencia protagonizado por las redes sociales digitales y otras temáticas que van más allá de la ficción.
Platelet-Rich Plasma in the Treatment of Facet Mediated Low Back Pain: A Comprehensive Review
Authors: Patel Aakash , Koushik Sarang , Schwartz Ruben , Gritsenko Karina , Farah Fadi , Urits Ivan , Varrassi Giustino , Viswanath Omar , Shaparin Naum
Published: July 2022

Background

Facet-mediated pain is a major cause of low back pain and as a result, is a significant cause of morbidity, including disability and reduced functionality.

Setting

The present investigation involved a PubMed literature review between June 1, and 2021-January 1, 2022.

Methods

We systematically reviewed was carried Pubmed using the search terms “platelet-rich plasma”, “inflammatory mediators”, “facet arthropathy”, “axial back pain”, and “leukoreduction”. Data extraction and quality assessment were performed by 3 independent reviewers. Out of the studies analyzed 2 were retrospective, while 1 was a prospective study.

Results

PRP injections for facet mediated or modulated pain are an alternative to conventional pharmacotherapies and interventional injections/radiofrequency. There are limited numbers of studies in world literature at present.

Limitations

Small number of articles in the world literature and small numbers of patients in those published studies.

Conclusions

At present, there are limited studies in the literature; however, larger well-designed studies are warranted to precisely understand efficacy, potential side effects and best practice techniques for PRP injections for facet mediated or modulated pain.
Reporte de un caso de Acariásis en un erizo pigmeo africano (Atelerix albiventris) en Maracay, Venezuela
Authors: Sanoja-Rondón Mariely , Dacak-Aguilera Diego Augusto , Rivera-Pirela Sergio Emiro , Lucero-Suzuki Mónica Hitomi , Cunha Felipe Rosa , Venturo-Barriga Renzo Andrés , Guzmán-Rodríguez Jorge , Ordoñez Andrés Renato
Published: July 2022

El erizo pigmeo africano (Atelerix albiventris) es un mamífero insectívoro de hábitos nocturnos considerado dentro de los nuevos animales de compañía. El objetivo de este reporte fue describir el caso inédito de un erizo pigmeo africano macho de 4 meses (mes) de edad, infestado con Caparinia tripilis en la ciudad de Maracay en Venezuela. En el examen clínico se evidenció prurito, rascado y áreas con pérdida de la densidad de púas o espinas finas costras blanquecinas en el área de la cara y patas. Se realizaron raspados cutáneos y se recogieron muestras para análisis de laboratorio, la microscopía reveló la presencia del ácaro C. tripilis. Se utilizó ivermectina en suspensión a dosis de 0,2 miligramos·kilogramos-1 (mg·kg-1) vía oral, una vez al día PO (per oral), SID (semel in die), por 3 días (d) y se continuó 1 vez por semana (sem), por 3 sem, en conjunto con Fipronil tópico cada 10 d, por 1 mes. Así mismo, se recomendó mejorar la higiene de la jaula y del ambiente. Esto conllevó a la resolución del cuadro clínico dermatológico y como consecuencia, el crecimiento de las espinas. Esta combinación probó ser efectiva 30 d después del tratamiento, evaluado mediante raspados cutáneos negativos; siendo ésta su última evaluación. La ivermectina oral y el fipronil tópico combinados fueron no invasivos y generaron menos estrés para el paciente.
Imparare dall’emergenza
Authors: Cortese Caterina , Licursi Sabina , Pascucci Roberta , Quarta Serena , Zucca Gianfranco
Published: July 2022

Le persone senza dimora hanno pagato un prezzo elevatissimo nella fase iniziale della pandemia da Covid-19, quando l’appello responsabile #iorestoacasa è suonato come un paradosso. Al contempo, i servizi di accoglienza hanno dovuto immediatamente adattare le strutture alle misure di emergenza nazionali. L’indagine ha avuto lo scopo di analizzare gli effetti della pandemia sui servizi per la grave marginalità, le risposte organizzative adottate, i risvolti sul lavoro degli operatori sociali e sulle persone senza dimora. Sono stati infine messi in luce gli apprendimenti e gli sviluppi futuri degli interventi nel campo della grave emarginazione adulta. ******************************** EN: Since the early stages of the pandemic, homeless people have suffered the effects of the healthy emergency, as the appeal for #Stayathome sounded like a paradox for those living rough. Furthermore, homelessness services have been rapidly reorganized in order to respond to national emergency measures. The article aims to analyze the effects of pandemic emergency on homelessnes services, focusing on the ability of the providers to manage the reorganization, on the changing of social work, and on the impact on homeless people. Moreover, learning from pandemic and challenges for the future have been highlighted
L'intrigo del decidere
Authors: Marzo Raffaele
Published: July 2022

L’articolo esamina la relazione tra politica, ricerca scientifica e diritto allorquando è necessario adottare provvedimenti che tengano conto di nuove acquisizioni scientifiche, analizzando nello specifico talune dinamiche emerse nella gestione della vicenda pandemica. Il contributo approfondisce le connotazioni degli oggetti della riflessione, le divergenze e i punti di incontro. Infine, si riporta la posizione della Corte costituzionale ed è stimata l’opportunità, incoraggiata dalla peculiarità della vicenda pandemica, di una qualche forma di collaborazione, perché laddove la scienza intenda offrire al diritto una pluralità di soluzioni – almeno alcune delle quali apparentemente valide e sostenibili – il legislatore dovrà scegliere quella conforme ai principi che sovraintendono all’ordinamento e, dunque, rispettosa dei diritti degli individui. EN: The article examines the relationship between politics, scientific research and law when it is necessary to adopt measures that take into account new scientific findings, specifically analysing certain dynamics that emerged in the management of the pandemic. The contribution explores the connotations of the objects of reflection, the differences and the meeting points. Finally, the position of the Constitutional Court is reported and the opportunity for some form of collaboration is estimated, an opportunity encouraged by the peculiarity of the pandemic case, because where science intends to offer the law a plurality of solutions - at least some of which apparently valid and sustainable - the legislator will have to choose the one compliant with the principles governing the legal system and, therefore, respectful of the rights of individuals