bluuebunny/crossref_metadata_2025 huggingface dataset:
The Plays of Shakespeare
Authors: Cahn Victor L.
Published: May 2024

Touching viewers and readers with his presentation of social, moral, and political issues, Shakespeare holds ageless and unequaled appeal primarily because of the universal themes at the heart of his dramatic works. Shakespeare scholar Victor Cahn takes a unique approach to exploring the plays by identifying and explicating the themes that recur throughout the canon. Written in lively language, each of the 35 essays explores a core theme or topic and discusses its implications in several key plays in which it figures prominently. This user-friendly guide not only allows readers to better understand the significance of concepts such as power, politics, marriage or money; the organization by theme also helps users to compare and contrast these important topics across relevant plays. Cahn draws vivid connections between related works of Shakespeare, but just as importantly, enlightens readers as to the pertinence of these themes in contemporary life.

While this thematic guide examines all of Shakespeare's plays, particular attention is devoted to those works most often read by students; the tragedies such asRomeo and Juliet, Julius Caesar, Hamlet, andMacbeth, the comedies includingA Midsummer Night's DreamandMerchant of Venice, as well as the historical plays likeRichard II, and the romantic works such asThe Tempest. Students who wish to investigate a particular play in greater depth can refer to this book's title index to identify all citations of that work. This valuable literary resource serves myriad uses, enabling students to trace the thread of a theme, to compare its treatment in several plays, and to understand better a play, its characters, plot and language, by examining Shakespeare's central themes.
The Pleasure of Poetry
Authors: Nelson Nicolas H.
Published: May 2024

The poetry produced by the British poets of the 17th and 18th centuries is considered to be among the best ever written. But many general readers feel intimidated by the language or structure of the poetry, and so tend to shy away from enjoying these poets and their works. Nelson takes readers on a tour of the major works and figures of 17th- and 18th-century British poetry, explaining major themes, devices, styles, language, rhythm, sound, tone, imagery, form, and meaning. Beginning each chapter with a sketch of the poet's life and career, the author then looks at five or six representative works, helping readers understand and appreciate the beauty of poetry itself.

From Donne and Jonson, to Pope, Swift, and Burns, the book offers excerpts of the poetry these artists crafted, and carefully examines the various attributes that have helped to establish them as some of the greatest of all time. Writing in clear, accessible language, Nelson also introduces general poetry terms to the novice, providing examples and explanations where necessary. Readers will no longer feel intimidated by difficult poetry. Instead, they will walk away with the tools they need to read, understand, and appreciate these titans of British letters.
Police Misconduct in America
Authors: Champion Dean John
Published: May 2024

With just the right dose of academic pragmatism,Police Misconduct in Americaassesses the history of police excesses from 1900 to the present.

At the dawn of the profession, police officers initially were hired based on physical strength, not personal skills. They did not understand the laws they were enforcing or how laws should be enforced. This extensive survey examines the context and types of police misconduct since the 1900s.

Written by Dean J. Champion,Police Misconduct in Americacovers police history back to Mesopotamia, outlines controversies, provides a broad chronology of significant eras in police history and a timeline of specific events, and offers biographical sketches of key personalities from J. Edgar Hoover to Alice Stebbens Wells, the first American policewoman. It also includes are summaries of key Supreme Court cases, an extensive list of organizations concerned about police misconduct, government documents and agency publications, and other references.
Pop Culture Russia!
Authors: Beumers Birgit
Published: May 2024

A revealing look at contemporary Russian popular culture, exploring the historical and social influences that make it unique.

Pop music is only one aspect of contemporary Russian culture that has taken some unexpected turns in the chaotic aftermath of the Soviet Union's collapse. Television and advertising, theater and cinema, athletics and religion, even fashion and food now reflect more exposure to the West, yet remain in essence distinctively Russian.

Pop Culture Russia!introduces readers to the fascinating, often surprising, post-Soviet cultural landscape. With chapters on media, the arts, recreation, religion, and consumerism, the book offers an insightful survey of Russian mass culture from the death of Stalin in 1953 to the present, exploring the historical significance of important events and trends, as well as the social and political contexts from which they emerged.
A Portrait of the Israeli Soldier
Authors: Gal Reuvan
Published: May 2024

No army in the Middle East has been as written about in English as has Israel's, yet this book actually says something new. Reuven Gal, former chief psychologist of the IDF, looks at the influences on the Israeli soldier and their impact on the IDF's performance. He is able to deal with issues such as motivation and camaraderie, leadership and heroism from a human viewpoint. . . . a detailed assembly of data such as this one is welcome, and the sociological-psychological jargon is kept at a minimum. This is neither hagiography nor psychobabble, and it contains a great deal of detail.Middle East Journal
La guerra en los primeros cien días de ARENA
Authors: Cañas Antonio
Published: May 2024

Más que hablar de lo que el gobierno de ARENA pretende hacer con el problema de la guerra se trata de establecer cómo, qué y cuánto utilizará el ejército, para sus fines bélicos, la política puesta en marcha por ARENA. El autor sostiene que la inestabilidad y flexibilidad de la coyuntura de transición a un nuevo gobierno agudizan las diferencias ya existentes en el medio militar. Las estrategias y tácticas contrainsurgentes, incluidas la acción cívica y las operaciones psicológicas, son independientes del partido en el poder y de sus planes de gobierno.
ECA Estudios Centroamericanos, Vol. 44, No. 490-491, 1989: 669-682.
Agosto-septiembre
Authors: ECA: Estudios Centroamericanos
Published: May 2024

No hay resúmenes disponibles.
ECA Estudios Centroamericanos, Vol. 44, No. 490-491, 1989: 727-743.
Biological defence through the civil protection system analysis and suggestions from the perspective of CBRN defence doctrine
Authors: Orehovec Zvonko , Orehovec Karlo , Črnko Marina
Published: May 2024

Natural and anthropogenic biological threats very often cause mass casualties and destruction, with long-term repercussions to the economy, welfare, security and political stability, and ultimately, to the future progress of the state and its society. For these reasons, the EU Member States have developed national and joint doctrines and strategies that provide for defence systems against the above threats, based on mass mobilization and mass response of all available capacities. The joint military response resides within NATO’s Joint CBRN Defence apparatus, while the civilian counterpart system is within the EU’s Civil Protection Mechanism. At the national level, each country develops its own, yet compatible systems. In the Republic of Croatia, strategic documents and laws on the development of the Homeland Security System and the Civil Protection System have been adopted. Biological threats, such as the current COVID-19 pandemic, are among such developments and require a systemic response. However, hardly anywhere in the world, not even in the EU and its Member States, have the relevant response systems worked.
The role of marketing as a determining factor in the production and sale of fashion apparel
Authors: Javadzada-Talibova Gunay Afrasiyab  , Salehzadeh Gulchohra Saleh
Published: May 2024

Marketing in the fashion sector gained widespread popularity in the 20th century, particularly after World War II, when the fashion industry became one of the most successful and flourishing sectors of the economy. It was during this century that fashion houses such as Chanel, Christian Dior, Elsa Schiaparelli, and Balenciaga emerged. Fashion evolved into a socio-economic phenomenon that not only reflected societal changes but often initiated them. The fashion world underwent various changes depending on the geopolitical situation, wars, and developments in science and sports. Marketing serves as a regulator of both direct and feedback interactions between consumption and production. Active use of marketing allows producers to organize their activities considering consumer interests, to solve market problems in the most rational way, to maximize profit opportunities, and to plan activities based on anticipated market development trends.
Технологии управления операционными потоками в банковской системе
Authors: Найзабаева Лязат , Жанилсаева Айша
Published: May 2024

Статья посвящена анализу применения технологий управления операционными потоками в банковской системе. В работе исследуются различные аспекты интеграции современных технологических решений, таких как автоматизация, бизнес-процессное управление (BPM) и искусственный интеллект, в операционные процессы банков. Основное внимание уделяется оценке влияния этих технологий на производительность банка, снижение операционных затрат и повышение уровня клиентского обслуживания. Авторы представляют результаты кейс-стади, проведенных в нескольких банковских учреждениях, и демонстрируют, как технологические инновации могут способствовать оптимизации банковских процессов и укреплению их конкурентных преимуществ.
A MORTE, OS RITUAIS FUNERÁRIOS E AS CONCEPÇÕES DE MUNDO EM DIFERENTES RELIGIÕES
Authors: Pereira Antonio Renaldo Gomes , Guerra Avaetê de Lunetta e Rodrigues
Published: May 2024

Desde os primórdios da história da humanidade, as diferentes visões sobre a morte têm desempenhado um papel crucial na organização das sociedades e na formação das identidades, tanto a nível individual quanto coletivo. Ao analisarmos a importância da morte como um fenômeno antropológico e religioso, somos levados a compreender a complexidade da condição humana, sendo desafiados a refletir sobre a vida e a busca por significado em um mundo marcado pela finitude e pelo desconhecido. Este artigo se propõe a investigar as visões e rituais associados à morte e sua relação com o sagrado em cinco tradições religiosas distintas, são elas: cristianismo, islamismo, judaísmo, hinduísmo e religiões afro-brasileiras. A fim de responder aos objetivos propostos, utilizamos uma metodologia de natureza bibliográfica, envolvendo a revisão e análise de obras e estudos acadêmicos que abordam as concepções de morte e sua relação com o divino nas religiões citadas. Conclui-se que a investigação da morte e sua relação com o divino revela as diferenças entre as tradições religiosas e suas semelhanças fundamentais, como a busca por transcendência e o desejo de conexão com algo maior. Nesta perspectiva, a morte, longe de ser apenas um fim, se mostra um elo vital na contínua busca humana por sentido e espiritualidade.
Identification of ice-over-water multilayer clouds using multispectral satellite data in an artificial neural network
Authors: Sun-Mack Sunny , Minnis Patrick , Chen Yan , Hong Gang , Smith Jr. William L.
Published: May 2024

Abstract. An artificial neural network (ANN) algorithm, employing several Aqua MODerate-resolution Imaging Spectroradiometer (MODIS) channels, the retrieved cloud phase and total cloud visible optical depth, and temperature and humidity vertical profiles is trained to detect multilayer (ML) ice-over-water cloud systems identified by matched 2008 CloudSat and CALIPSO (CC) data. The trained multilayer cloud-detection ANN (MCANN) was applied to 2009 MODIS data resulting in combined ML and single layer detection accuracies of 87 % (89 %) and 86 % (89 %) for snow-free (snow-covered) regions during the day and night, respectively. Overall, it detects 55 % and ∼ 30 % of the CC ML clouds over snow-free and snow-covered surfaces, respectively, and has a relatively low false alarm rate. The net gain in accuracy, which is the difference between the true and false ML fractions, is 7.5 % and ∼ 2.0 % over snow-free and snow/ice-covered surfaces. Overall, the MCANN is more accurate than most currently available methods. When corrected for the viewing-zenith-angle dependence of each parameter, the ML fraction detected is relatively invariant across the swath. Compared to the CC ML variability, the MCANN is robust seasonally and interannually and produces similar distribution patterns over the globe, except in the polar regions. Additional research is needed to conclusively evaluate the viewing zenith angle (VZA) dependence and further improve the MCANN accuracy. This approach should greatly improve the monitoring of cloud vertical structure using operational passive sensors.
Global catalog of soil moisture droughts over the past four decades
Authors: Řehoř Jan , Brázdil Rudolf , Rakovec Oldřich , Hanel Martin , Fischer Milan , Kumar Rohini , Balek Jan , Poděbradská Markéta , Moravec Vojtěch , Samaniego Luis , Trnka Miroslav
Published: May 2024

Abstract. At the global scale, droughts can be described by many variables, expressing their extent, duration, dynamics and severity. To identify common features in global land drought events (GLDEs) based on soil moisture, we present a robust method for their identification and classification (cataloging). Gridded estimates of root-zone soil moisture from the SoilClim model and the mesoscale Hydrologic Model (mHM) were calculated over global land from 1980–2022. Using the 10th percentile thresholds of soil moisture anomalies and OPTICS clustering of the gridded data in a 10-day interval, a total of 775 GLDEs from SoilClim and 630 GLDEs from mHM were identified. By utilizing four spatiotemporal and three motion-related characteristics for each GLDE, we established threshold percentiles based on their distributions. This information enabled us to categorize droughts into seven severity categories (ranging from extremely weak to extremely severe) and seven dynamic categories (ranging from extremely static to extremely dynamic). Our global-scale synthesis revealed the highest relative proportions of extremely severe and extremely dynamic GLDEs in the South American region, followed by North America, while the single longest and most extensive GLDEs occurred in Eurasia. The severity and dynamic categories overlapped substantially for extremely severe and extremely dynamic droughts but very little for less severe/dynamic categories, despite some very small droughts that have occasionally been very dynamic. The frequency of GLDEs has generally increased in recent decades across different drought categories but is statistically significant only in some cases. Overall, the cataloging of GLDEs presents a unique opportunity to analyze the evolving features of spatiotemporally connected drought events in recent decades and provides a basis for future investigations of the drivers and impacts of dynamically evolving drought events.
An Improved Geolocation Methodology for Spaceborne Radar and Lidar Systems
Authors: Puigdomènech Treserras Bernat , Kollias Pavlos
Published: May 2024

Abstract. Geolocation and co-registration methodologies are essential for the accurate interpretation of observations from spaceborne remote sensors. In preparations for EarthCARE, here, we refine the definition of these techniques and present various examples of geolocation assessments. The geolocation methods build upon earlier work, however, introduces several improvements that have increased the reliability of the geolocation accuracy. The EarthCARE active sensors geolocation methods use coastlines and significant elevation gradients, in both statistical and numerical ways. The effectiveness of the proposed geolocation methods was tested using the extensive record of CloudSat and CALIPSO observations. The EarthCARE active sensors geolocation methods were effective in identifying and correcting a short period of CloudSat observations when the star tracker was not operating properly. In addition, the geolocation methods were able to reproduce the excellent geolocation record of the CloudSat and CALIPSO missions.
Building extraction in urban and rural areas with aerial and LiDAR DSM
Authors: Hattula Emilia , Zhu Lingli , Raninen Jere
Published: May 2024

Abstract. Automatizing the extraction of different objects from remote sensing data with deep learning methods has been a popular research topic. Buildings have been one of those popular objects to be extracted. Not only does the selection of neural network affect the results and accuracy of extracted buildings, but also the selection of different types of data for the task. Digital surface models (DSMs) are increasingly used in remote sensing and their demand has increased. Retrieving height information from surface models has proved helpful for accurate extraction of buildings. In this study was investigated, if the use of light detection and ranging (LiDAR) DSMs and DEMs with 25 cm pixel resolution will lead to more accurate building extraction results in comparison to the use of aerial DSMs. Results with UNet models trained with building vector labels, DSMs, DEMs and true orthophotos from multiple areas of Finland, were produced with different data combinations from two Finnish cities, Savonlinna and Pudasj¨arvi, to see, which combination would lead to the most accurate building detection results. Results were evaluated partly by visual inspection, and partly by quantitative assessment. Based on the tests carried out, combining the information from true orthophotos with LiDAR DSMs and 25 cm DEMs provided the most accurate results. In forest area, using LiDAR data increased the accuracy of building detection. However, in urban area, due to missing buildings from LiDAR data, its advantages were compromised. We suggest that the use of both imagery and LiDAR data should be the optimal solution.
Integration of GIS and CAD data to perform interactive preliminary environmental analyses at district scale
Authors: Tsai Bing-Shiuan , Huizer Lars , Giampaolo Michele , Monté Sérénic , Gong Sicong , Garcia Gabriel , Agugiaro Giorgio
Published: May 2024

Abstract. This paper describes the proposed methodology, the implementation, and the experience resulting from the further development of a tool, embedded in Rhinoceros/Grasshopper, that allows to perform preliminary environmental analyses at district scale in the case of a new planned building. The CAD-based parametric 3D model of a “new” building, generated in Grasshopper, is enriched with and embedded into a 3D urban scene of the block/district where it is planned to be built. The resulting 3D scene is then used to perform shadowing, solar and wind analyses that are used by architects and engineers in their preliminary development phases of the project. The work stems from a preliminary analysis in terms of data and software requirements carried out between practitioners from both the GIS and AEC domain.More in detail, a series of modules in Grasshopper have been developed that allow to import GIS “surrounding” data at district scale (e.g. buildings, terrain) and to blend them with the “new” building model, in order to perform environmental analyses in (near) real time while the designer interactively changes the design parameters of the building and its position. The paper presents the results and discusses the inherent limitations.
Automating Built Heritage Modelling for the Integration into 3D City Models
Authors: Aboohamzeh Ali , Avena Marco , Spanò Antonia
Published: May 2024

Abstract. The interest in studies on 3D city models has renewed over time thanks to technological innovations that concern the methods of data acquisition and automatic classification of unstructured point clouds, to model increasingly specialized geometric objects for the growing needs of urban transformation management. Managing geometric and semantic information in cognitive systems, based on standards, increasingly open to the inquiries, analyses, and predictions that today are necessary to implement for future assessments, can digitally twin reality. The problem focused on in this work is the modelling phase, which requires efficient automatisms to make the production phase of geometric objects more sustainable, whether they are then destined to become parametric features in a BIM/CIM environment or 3D geometric objects of a geodatabase.A comprehensive methodology for automating the generation of 3D meshes from point cloud data using Python code, with a focus on practical implementation is presented parallelly to evaluations regarding the generation of the geometric 3D contents of the urban environment representation, depending on whether or not it includes examples of architectural heritage (of all ages). Leveraging the Open3D library and NumPy, the methodology provides different experiences, tests, and related discussions in the field of architectural and urban 3D surface reconstruction and visualization. The paper outlines essential steps including data loading and preparation, meshing strategy selection, data processing using Poisson reconstruction, and mesh exportation and visualization. Additionally, a method for generating multiple Levels of Detail (LoD) meshes is introduced, enhancing the applicability of the approach for city modelling framework applications, including architectural elements of buildings. The presented Python code serves as a practical resource for implementing 3D mesh generation workflows seamlessly.
Vibration-based water leakage detection system for public open data platforms
Authors: Giaconia Giuseppe Costantino , Lo Valvo Fulvio , Ladjery Karim , Di Puma Francesco , Falla Josè , Christou Ioannis T. , Soldatos John , Papadakis Thanasis , Popunkiov Boian , Alexieva Daniela , Raykov Dian
Published: May 2024

Abstract. Water Distribution Networks are known to lose a consistent percentage of drinkable water due to the presence of leakages. In this paper it is proposed a solution to detect water leaks consisting of: i) a new sensing equipment able to acoustically monitor the external surface of a newly laid underground pipe; ii) a training of several machine learning models able to analyse the data collected by the new sensing equipment; iii) a user dashboard to give the final user the possibility to monitor the pipe’s condition. The research process included the generation of artificial leakages capable to produce a suitable dataset necessary to properly train machine learning models onto.
Perwujudan Trauma Healing Melalui Kegiatan Perlombaan Dan Kerohanian
Authors: Aisah  , Aldi Saputra  , Mutiara Nabila F  , Mutiara Nurfatimah A  , Dila Padila Nurhasanah  , Muhammad Riswan
Published: May 2024

Kegiatan trauma healing ini dilaukan di desa Cibulakan yang mana sasaran utama dalam kegiatan ini adalah anak-anak SDN CIBULAKAN yang terdampak bencana gempa. Kegiatan yang dilakukan berupa pendampingan mahasiswa bersama siswa/i SDN CIBULAKAN, pada kegiatan ini kami melakukan formulasi dan kebijakan perencanaan yang inovatif dan partisipatif untuk menjalankan trauma healing guna mengatasi kecemasan pasca gempa, dimana target utama dari trauma healing ini untuk penyembuhan anak-anak di desa cibulakan. Tujuan dilakukannya kegiatan trauma healing oleh mahasiswa Universitas Nusa Putra untuk anak-anak dalam mengurangi rasa trauma dan memulihkan emosional kondisi anak-anak pasca gempa, guna membantu semangat kembali seperti semula. Kegiatan ini dilangsungkan dengan perlombaan-perlombaan yang dapat membantu anak-anak pulih dari keadaan trauma akibat gempa. Perlombaan yang kami adakan berkaitan dengan intelegensi dan kemampuan berkonsentrasi, seperti perlombaan mewarnai, kaligrafi, adzan, LCC, dan Pidato. Perlombaan yang kami adakan juga diselingi dengan pengetahuan-pengetahuan terkait pengembangan karakter pada anak. Dalam melakukan pelaksanaan trauma healing menggunakan metode yaitu Participatory Learning and Action dimana dilakukan dengan proses belajar kelompok suatu proses yang langsung secara berkomunikasi dan berinteraksi kepada masyarakat.
 
Kata kunci:    Gempa, Trauma Healing, anak-anak
Strategi Bisnis Fashion Batik Tulis Sukabumi untuk Meningkatkan Permintaan Batik Tulis Sukabumi dengan Menggunakan Analisis SWOT
Authors: Suci Nur Imelda  , Simangunsong Bonse Aris Mandala Putra
Published: May 2024

Penjualan batik tulis mengalami penurunan yang signifikan disebabkan oleh berbagai faktor, termasuk perubahan selera konsumen, dampak pandemi, persaingan dengan batik cap dan batik printing, serta harga yang lebih tinggi. Penurunan permintaan dan penjualan batik tulis dapat menyebabkan penghasilan para pengrajin menurun, sementara kurangnya minat generasi muda dalam industri ini mengancam kelangsungan seni dan keterampilan batik tulis di masa depan. Keberhasilan busana casual sebagai selera pasar yang signifikan menjadi peluang untuk memperkenalkan batik tulis kepada lebih banyak konsumen. Dalam rangka mencapai tujuan tersebut, penelitian ini dilakukan dengan melakukan wawancara kepada pengrajin, analisis SWOT, serta perhitungan IFAS dan EFAS untuk menentukan faktor yang berkaitan dengan permintaan batik tulis. Hasil analisis menunjukkan bahwa strategi bisnis yang tepat adalah pertumbuhan dan pembinaan. Strategi pertumbuhan berfokus pada pengembangan dan ekspansi bisnis, sementara strategi pembinaan berfokus pada memperkuat dan meningkatkan aspek-aspek internal organisasi. Diharapkan penelitian ini dapat menjadi referensi bagi pengrajin batik tulis di Sukabumi untuk meningkatkan industri batik tulis dan menjadikan batik tulis sebagai bagian dari tren busana casual yang diminati oleh konsumen.
Pengaruh Kualitas Produk, Kualitas Pelayanan, dan Suasana Toko Terhadap Kepuasan Pelanggan
Authors: Andita Febriyanti
Published: May 2024

Penelitian ini bertujuan untuk menguji pengaruh kualitas produk, kualitas pelayanan dan atmosfer toko terhadap kepuasan pelanggan di Restoran Noble One Jakarta. Sebanyak 120 responden yang merupakan pelanggan Restoran Noble One Jakarta berpartisipasi dalam penelitian ini. Data dikumpulkan melalui kuesioner yang berisi pertanyaan terkait kualitas produk, kualitas pelayanan, suasana toko dan kepuasan pelanggan. Hasil analisis menggunakan perangkat lunak SPSS menunjukkan bahwa kualitas produk, kualitas pelayanan dan suasana toko memiliki pengaruh positif dan signifikan terhadap kepuasan pelanggan di Restoran Noble One Jakarta. Temuan ini memberikan wawasan berharga bagi manajemen restoran dalam meningkatkan kualitas produk, kualitas pelayanan dan suasana toko untuk meningkatkan kepuasan pelanggan dan mempertahankan loyalitas pelanggan.
POLITIK HUKUM PEMINDAHAN IBU KOTA NEGARA BERDASARKAN UU NO 3 TAHUN 2022 TENTANG IBUKOTA NEGARA DITINJAU DENGAN TEORI TUJUAN HUKUM
Authors: Utama Erry Praditya
Published: May 2024

Pemerintah di bawah kepemimpinan Presiden Jokowi telah menetapkan kebijakan pemindahan ibu kota dari Jakarta ke Kalimantan melalui Undang-undang No. 3 tahun 2022 tentang Ibu Kota Negara (“IKN”). Kebijakan ini mengundang beragam tanggapan dan kritik dari berbagai kalangan karena ibu kota memiliki peran yang fundamental bagi negara ini dan secara historis peran ibu kota sudah begitu lama diemban oleh Jakarta. Lalu kenapa pemerintah mengambil keputusan besar untuk memindahkan Ibu Kota? Alasan, gagasan, atau ide pemindahan Ibu Kota Negara ini dapat kita pahami dengan mempelajari Politik Hukum pembentukan UU IKN. Dalam konsideran dan bagian penjelasan, pada intinya dijelaskan bahwa pembangunan IKN diperlukan guna pemerataan pembangunan di luar pulau Jawa, serta dikarenakan Jakarta sudah tidak mampu mengembang peran sebagai Ibu Kota Negara yang ideal. Pemerintah berharap Ibu Kota Negara Indonesia ke depannya dapat menjadi benchmark di mata negara-negara lain di dunia serta menjadi kebanggaan Indonesia. Mengacu pada kajian Politik Hukumnya, dengan mengkaitkan gagasan UU IKN terhadap teori Tujuan Hukum dari Gustav Radbruch maka dapat disimpulkan bahwa pembangunan IKN sudah memenuhi tujuan hukum dalam mewujudkan keadilan, kemanfaatan dan kepastian hukum. Namun Pemerintah perlu menerapkan prinsip kehati-hatian dan Good Corporate Governance dalam pembangunan berkelanjutan IKN, menghindari terjadinya ketidakadilan, khususnya terhadap para penduduk asli IKN, hal ini agar tidak terjadi kegagalan yang akan merugikan Negara.
Wilhelm von Humboldt : le signe linguistique en question
Authors: Chabrolle-Cerretini Anne-Marie
Published: May 2024

Il s’agit ici de mettre en évidence dans l’approche systémique du langage et des langues de Humboldt les conceptions de l’organisme, système qui rayonne sur l’ensemble du projet théorique jusqu’à l’unité minimale de la langue.
Validación inicial de ensayo de secuenciación masiva en biopsia líquida para detectar el marcador oncogénico PIK3CA en pacientes con cáncer de mama
Authors: Maldonado Brito Isabel Denisse , Vera Leonelli Valentina Belén , D'Achiardi Meza Isabella Sofía
Published: May 2024

Introducción: En Chile, las técnicas aprobadas para la detección de mutaciones en biopsias líquidas son variantes de la reacción en cadena de la polimerasa, siendo la técnica de referencia. No obstante, la secuenciación masiva presenta ventajas, sirviendo para el monitoreo y selección del tratamiento de patologías como el cáncer de mama. Según estándares de laboratorio clínico internacionales, se realizó la comparación de la técnica evaluada con la de referencia, necesarias para la validación e implementación en pacientes con cáncer de mama. Objetivo: Realizar la validación inicial de un protocolo de secuenciación masiva capaz de detectar mutaciones en PIK3CA del ADN tumoral circulante de dichos pacientes. Metodología: Se obtuvieron 11 muestras de sangre de pacientes con cáncer de mama avanzado, donde se realizó la secuenciación del ADN extraído y se evaluó la detección de tres mutaciones en PIK3CA mediante una reacción en cadena de la polimerasa, y los resultados se compararon mediante una tabla de contingencia y la prueba de McNemar. Resultado: La prueba exacta de McNemar dio un valor p>0,05 y la técnica evaluada tuvo una sensibilidad y especificidad del 100%, con una concordancia de 1. Discusión: La costo-efectividad de la secuenciación masiva es mayor por sobre los ensayos genéticos singulares, pero se deben tener en cuenta las limitaciones de ambas técnicas. Conclusión: Se encontró un alto nivel de concordancia entre las técnicas, pero los resultados no fueron estadísticamente significativos. Aun así, se debería continuar la validación de este ensayo en el futuro con un número mayor de muestras
Prospects for the production of probiotic beverages
Authors: Пашина Л.Л. , Шкрабтак Н.В. , Фролова Н.А.
Published: May 2024

В настоящее время интерес потребителей к ферментированным продуктам на растительной немолочной основе вырос в связи с гиполактазией. Пробиотики, содержащиеся в зернах водного кефира, характеризуются способностью к подавлению роста патогенных бактерий, связывания токсинов, выработке ферментов для нейтрализации бактериальных токсинов, косвенно «модулируя» иммунную систему организма. Целью работы явилось получение напитка функционального назначения на основе растительных компонентов и гранул водного кефира с последующим анализом растворимых сухих веществ во время ферментации. Результаты проведенных исследований показали, что температура ферментации, концентрация сахара и морковного сока влияют на содержание сухих веществ и сенсорные свойства готового напитка. Максимальное количество сухих веществ отмечено в образцах напитка, полученных при температуре 25 °C с содержанием 10 % сахарозы, время ферментации которых составило 24 ч. После 48- и 72-часовой ферментации происходит снижение содержания сухих веществ на 0,5 и 1 % соответственно. Антиоксидантный комплекс, содержащийся в напитке, продемонстрировал отличную способность к удалению DPPH – 9,88–63,17 % и ингибированию окисления аскорбата на уровне 6,08–25,57 %. Установлено, что наиболее оптимальными образцами с точки зрения вкуса и содержания сухих веществ явились образцы напитка, содержащего 10 % сахара и 10 % морковного сока, ферментированные при температуре 25 °C в течение 48 ч, при этом срок годности напитка с учетом выживаемости микроорганизмов составил 5 сут.

Currently, consumer interest in fermented non-dairy plant-based products has increased due to hypolactasia. Probiotics contained in water kefir grains are characterized by the ability to suppress the growth of pathogenic bacteria, bind toxins, and produce enzymes to neutralize bacterial toxins, indirectly «modulating» the body's immune system. The aim of the work was to obtain a functional drink based on plant components and granules of aqueous kefir with subsequent analysis of soluble solids during fermentation. The results of the conducted studies have shown that the fermentation temperature, sugar concentration and carrot juice concentration affect the dry matter content and sensory properties of the finished drink. The maximum amount of dry substances was noted in the beverage samples obtained at a temperature of 25 °C with a content of 10% sucrose, the fermentation time of which was 24 hours. After 48 and 72 hours of fermentation, the dry matter content decreases by 0.5 % and 1 %, respectively. The antioxidant complex contained in the drink demonstrated excellent ability to remove DPPH – 9.88–63.17 % and inhibit ascorbate oxidation at the level of 6.08–25.57 %. It was found that the most optimal samples in terms of taste and dry matter content were samples of a drink containing 10 % sugar and 10 % carrot juice fermented at a temperature of 25 °C for 48 hours, while the shelf life of the drink, taking into account the survival of microorganisms, was 5 days.
PRACTICAL ASPECTS OF DEVELOPMENT OF LITERARY READING SKILLS IN UZBEK LANGUAGE CLASSES
Authors:   Alisher Navo'i Tashkent state university of Uzbek language and literature, Turakulova Okila
Published: May 2024

This article provides some methodological recommendations for developing literary reading skills in Uzbek language classes, practical aspects of working with text to develop literary reading skills.
LINGUISTIC PROBLEMS IN NORMATIVE-LEGAL DOCUMENTS IN THE FIELD OF TAX
Authors:   Alisher Navo'i Tashkent state university of Uzbek language and literature, Beysenova Azoda , Kadirova Xurshida ,   Alisher Navoi Tashkent State University of Uzbek Language and Literature
Published: May 2024

his article explains the legal basis of linguistic expertise, the importance of linguistic expertise of normative legal documents, in particular, internal documents related to the tax field. Errors in the document related to the tax field were listed, and with this, the importance of working with documents in the Uzbek language was mentioned to the students of the Russian group of the tax field.
METHODS OF MAKING ASSIGNMENTS FOR AUTHENTIC MATERIALS IN TEACHING UZBEK AS A FOREIGN LANGUAGE
Authors:   Alisher Navo'i Tashkent state university of Uzbek language and literature, Shodmanov Temurxo‘ja
Published: May 2024

This article talks about the role of authentic materials in teaching the Uzbek language as a foreign language, their usage in language education, and the creation of tasks corresponding to authentic materials. Problems of using authentic materialsare analyzed and solutions are proposed. Given some examples of tasks that provide easier access to the live language environment for Uzbek language learners.
A study on consumer attitude towards Smoking amongst males and females of gen. Z in Ahmedabad
Authors: Gupta Kopal , Patel Prashant , Vidani Jignesh
Published: May 2024

This research paper provides valuable insights on the consumer behaviour towards smoking in Ahmedabad by focusing on both gender [males and females]. We have conducted the survey to gather the insights into habits and awareness related to smoking. This survey involves various types of people like students going to school and colleges, office going males and females of Gen. Z. This study involves the main reason of starting smoking are they all have same reason or problem for which they have started. The sampling method we have used here stratified sampling technique that ensures covers participants from different socioeconomic backgrounds within Ahmedabad. The factors we have taken into consideration are attitudes towards smoking, why it became their habit, and peoples reviews and recommendation for starting campaign or programs related to less consumption of smoking. Analysis done that shows that people of 21-25 smoke more because the main reason overall we got is the pressure and stress. The future scope for the research is to reduce the percentage of people who are currently and formally smoking by running a campaign or short and comedy programs. This study is not only focused of present situation pf consumer attitude towards smoking but to provide foundation for better future analysis in this field in Ahmedabad city. The outcomes we expected is the percentage of people smoking should reduce to low they understand the harmfulness behind smoking and stop it.
Analysing the usage of marketing audit and practical problems of its usage in marketing function
Authors: Talla Tejashri , Sil Ishita , Wasankar Vaibhav , Karodkar Mayuri , Gupta Sonal
Published: May 2024

The marketing function within a business is crucial for creating, communicating, delivering, and exchanging offerings that have value for customers, clients, partners, and society at large. It involves a range of activities including market research, product development, pricing, promotion, distribution, and customer relationship management. However, like any other business function, the marketing function can encounter practical problems, which necessitate auditing to ensure its effectiveness and efficiency. Considering these practical problems, conducting a marketing audit becomes essential to evaluate the effectiveness and efficiency of marketing activities and identify areas for improvement. A marketing audit typically involves assessing various aspects of the marketing function. The following research addresses that marketing audit like lack of realizing the value of the concept, perception that audit is a fault-finding activity, lack of awareness, perceived as a complex activity.
A retrospective review of the potential relationship between the TMT B and on-road driving performance within a community rehabilitation setting
Authors: Hinckley Andrea , Patterson Sarah , Matigian Nicolas
Published: May 2024

Aims: Occupational therapy (OT) driving assessments provide the gold standard approach to determine fitness to drive post-injury, medical event, and aging. However, these assessments are time intensive, costly and are associated with lengthy waitlists. As such, there is interest to investigate innovative approaches, including the use of the Trails Making Test B (TMT B), to assist clinicians with their decisions around returning to driving. The aim of this research was to explore potential correlations between TMT B scores and driving assessment outcomes.

Methods: Trails Making Test B data were collected between 2010 and 2019 within a publicly funded community-based driving service in Brisbane, which serviced a wide range of client diagnostic groups and age ranges (17–94 years). A retrospective analysis was completed to compare with the on-road OT driving assessment outcome.

Results: Results indicate a statistically significant relationship between TMT B score with on-road driving performance, with a higher confidence of predictability in the younger age groups (defined as 63 years or younger). Age is also related to on-road performance, with older clients more likely to fail. A 120 second time cut off may be a clinically relevant marker in predicting on-road performance, particularly for the younger clients.

Conclusion: The TMT B is useful tool to assist in the decision making around returning to driving to aid in the timing and need of on-road driving assessment and to potentially assist with decision making in situations where these assessments are not practically available. Clinicians can consider the risk versus the benefits of the test as a predictive tool given their specific contextual environment and access to on-road driving assessments.
IN VITRO-IN VIVO CORRELATION (IVIVC): TAMOXIFEN NANOSPHERES
Authors:   Faculty of Health and Allied Sciences, KAAF University College, Fetteh-Kakraba, Gomoa East District, Central Region Ghana, Yadagiri Phalguna , Wombeogo Michael
Published: May 2024

The primary goal of this study was to establish an in vitro-in vivo correlation (IVIVC) for tamoxifen (TAM)- loaded polycaprolactone-chitosan nanospheres. The plasma attention of TAM and time records have been used to calculate the pharmacokinetic parameters. Cmax for the nano spheres stayed determined to be 459.20 ng mL-1, compared to 442.20 ng mL-1 for natural TAM. Furthermore, the Wagner-Nelson technique was employed to compare the drug release profile by determining the in vivo fixation time data. In line with this, a level between the intestinal absorption in rats and the dissolution % for nanospheres loaded with TAM was created. Plotting the share absorbed in vivo vs the share launched in vitro simultaneously is the best way to illustrate a relationship.
IN SILICO MOLECULAR DOCKING STUDIES OF COUMARIN-CHALCONE HYBRIDS AGAINST SARS-COV-2 MAIN PROTEASE (6LU7)
Authors:   Department of Pharmaceutical Sciences, Vignan’s Foundation for Science Technology and Research, Guntur- 522 213, Andhra Pradesh, India, K. Konidala Sathish , Kotra Vijay , Samineni Ramu , R. Shaik Abdul , S. Nissankara Rao Lakshmi , N. Jamullamudi Risy , K. Kola Phani
Published: May 2024

The present work aimed to explore efficient lead molecules to combat against COVID-19. Despite the extensive usage of repurposed medications for COVID-19 therapy due to their inadequacy to proper control of endangered pandemic, there is an urgent need to discover innovative compounds that are very effective against the COVID-19 pandemic. Newly synthesized coumarin-chalcone hybrids were assessed for their efficacy to inhibit main protease 6LU7(Mpro) and compared it with some repurposing COVID-19 drug activity through in silico technique. Among all synthesized hybrids, d11, a11, c12, b11 and c5, showed highest binding affinities with the least docking score against protease (PDB ID: 6LU7) protein comparable to repurposed drugs currently used against COVID-19. The selected hybrids having coumarin, chalcone, and dihydropyridine pharmacophores are promising for their anti-COVID-19 activity. However, further extensive research is required through suitable in vitro and in vivo methods.
PREPARATION AND CHARACTERIZATION OF SOLID DISPERSION USEFUL IN MAKING SUBLINGUAL TABLETS OF PIROXICAM
Authors:   Department of Pharmaceutics, Shree Dhanvantary Pharmacy College, Kim, Surat-394 110, Gujarat, India, Goyani Manish , Suryawanshi Meghraj , Gandhi Nikunjkumar
Published: May 2024

This study aimed to investigate the usage of solid dispersion (SD) to enhance the dissolution rate of the poorly soluble drug piroxicam for sublingual formulation. Poloxamer grade 407 (Kolliphor® P-407), a commercially available polymer, was chosen, and various solid dispersions with different weight ratios of piroxicam and Poloxamer were prepared using the hot melt method. Compatibility tests using FTIR spectroscopy, DSC, and XRD were conducted to assess any chemical or physical interactions between the drug and polymer. In vitro dissolution tests were performed on the solid dispersions. The results of the FTIR spectroscopy study indicated no chemical interaction between the drug and the polymer. Similarly, the DSC and XRD analyses showed no physical interaction between the drug and the polymer. The maximum cumulative percentage release of the pure drug and the solid dispersion at 15 minutes were 40.90±1.83% and 99.56±3.25%, respectively. Based on these findings, it was concluded that the solid dispersion with a ratio of 2:1 (Drug: Poloxamer-407) showed a noteworthy upsurge in the dissolution rate in comparison to the pure drug.
Estimulação transcraniana por corrente contínua como estratégia fisioterapêutica em sintoma secundário da fibromialgia: um ensaio clínico randomizado
Authors: Melo Géssika Araújo de , Pontes Viviann Alves de , Araújo Gilvane de Lima , Maciel Mayza Leite Felix , Magalhães Mayara Cavalcanti , Madruga Marcela Laís Lima Holmes , Vasconcelos Aline Miranda de , Torro Nelson
Published: May 2024

A fibromialgia (FM) é uma condição caracterizada pela dor crônica difusa, frequentemente acompanhada por distúrbios do sono. O tratamento para ter melhores resultados deve envolver fisioterapia, terapia medicamentosa e demais profissionais da equipe multidisciplinar. A Eletroestimulação Transcraniana por Corrente Contínua (ETCC) emerge como uma terapia complementar promissora para melhorar o sono e qualidade de vida dessa população. Assim, objetivou-se verificar os efeitos de dois protocolos de ETCC para melhora de tempo de sono em mulheres com FM. O Projeto foi aprovado pelo Comitê de Ética em Pesquisa do Centro de Ciências da Saúde da Universidade Federal da Paraíba (CAAE: 39796914.5.0000.5188). Realizou-se um ensaio clínico duplo-cego, randomizado, controlado por placebo, com 31 mulheres com FM há pelo menos três meses, na faixa etária entre 25 e 60 anos de idade. Foram divididas em três grupos: dois grupos receberam ETCC ativa por 5 ou 10 dias, enquanto um grupo recebeu estimulação sham. A qualidade do sono foi analisada antes e após o tratamento usando análises descritivas e o teste ANOVA fatorial. Observou-se um aumento significativo nas horas de sono após a aplicação da ETCC ativa em ambos os grupos, com uma leve superioridade para o grupo de 10 dias de estimulação. Este estudo fornece dados promissores sobre o efeito da ETCC na qualidade do sono de mulheres com FM. A melhoria do sono pode ter implicações importantes na gestão da dor e na qualidade de vida desses pacientes. No entanto, são necessárias mais pesquisas para entender completamente os mecanismos subjacentes e sua relação com sintomas de dor.