bluuebunny/crossref_metadata_2025 huggingface dataset:
Lire les mots de Pierre Laborie… « parce qu’ils étaient eux-mêmes une histoire »
Authors: Loubes Olivier
Published: August 2020

Cet article donne à lire les mots de Pierre Laborie de deux façons. D’abord en analysant leurs fonctions essentielles dans l’écriture de l’histoire propre à Laborie. Puis en proposant une sélection de définitions de mots puisée aux textes mêmes de Pierre Laborie. Pour l’historien de l’imaginaire social, les mots sont cruciaux car son objet – les phénomènes d’opinion – est résistant aux lectures simples. Plus que d’autres, il nécessite « moins de parler des mots que de les faire parler ». Si on ajoute, au regard de son histoire personnelle, qu’ils aident à « faire reculer les ensevelissements de la mort », on comprend qu’ils jouent dans son œuvre un rôle crucial d’intercesseurs d’étrangeté (Carlo Ginzburg). C’est que, pour Pierre Laborie, les mots fonctionnent comme des écrans de temporalités, c’est-à-dire qu’ils nous permettent de restituer la concordance des temps de ce qui s’est passé dans les sociétés étudiées, futurs compris. En ce sens, ils sont « eux-mêmes une histoire ».
Physical, Chemical, and Microbiological Stability of Mucuna pruriens Effervescent Powders and Suspension
Authors: Chittasupho Chuda , Tadtong Sarin , Vorarat Suwanna , Kamkaen Narisa
Published: August 2020

Mucuna pruriens is a tropical leguminous plant containing L-dopa which is the main active ingredient for Parkinson’s disease therapy. The objective of this study was to investigate the physical, chemical, and microbiological stability of M. pruriens seed extract effervescent powders and suspension. The effervescent powders and suspension were prepared using freeze dried M. pruriens seed extract and were stored at 4 °C, 30 °C, and 45 °C. Physical stability was evaluated by observing appearance and determining rheological behavior. Chemical stability was evaluated by HPLC assay of L-dopa content in the formulation. Bacterial, fungal and mold contaminations were assessed by 3MTM PetrifilmTM count plates. Both formulations showed good physical stability. The degradations of L-dopa in effervescent powders and suspension were fitted to pseudo-zero order and second order kinetic models, respectively. M. pruriens seed extract effervescent powders was found to have the longest half-life, about 112 days, when it was stored at 4 °C. The results suggested that M. pruriens seed extract should be formulated in effervescent powders and stored at 4°C to prevent physical and chemical degradation.
Development and Evaluation of Thermally-Crosslinked Mucoadhesive GantrezTM S-97/Polyvinyl Alcohol/ Hyaluronic Acid-Catechol Nanofibers
Authors: Pornpitchanarong Chaiyakarn , Rojanarata Theerasak , Opanasopit Praneet , Ngawhirunpat Tanasait , Patrojanasophon Prasopchai
Published: August 2020

This study aimed to develop novel thermally crosslinked mucoadhesive nanofibers. The nanofiber patches were composed of mucoadhesive polymers which were catechol-bearing hyaluronic acid (HA-cat) and copolymer of methyl vinyl ether and maleic anhydride (GantrezTM, GT). Polyvinyl alcohol was used to improve the nanofiber properties. The nanofibers were prepared from a polymer mixture of 20 %wt GT, 10 %wt PVA, and 2 %wt HA-cat at different ratios using an electrospinning technique. Crosslinking process was performed by heat treatment at 130 °C for various durations. The appearances and chemical characteristics of the patch was evaluated using scanning electron microscope (SEM) and attenuated total reflectance Fourier-transformed infrared spectroscopy (ATR-FTIR), respectively. Moreover, the percentage of water insolubilization, tensile strength, and mucoadhesive property of the electrospun nanofibers were evaluated. Different polymer ratios provided identical nanoscale fibers. The patch prepared at the GT:PVA:HA-cat ration of 1:1:2 which provided the highest amount of catechol was selected. The optimal crosslinking time was 2 h under 130 °C in which the fiber diameters were not altered, and the highest percentage of water insolubilization was observed. Hydrogen and ester bond formation were established from the ATR-FTIR spectrum of the crosslinked patch. The patch could resist the force applied up to 4.82±0.46 N prior to deformation. In addition, the maximum detachment force from porcine buccal mucosa was 0.08±0.01 N. After all, the prepared electrospun mucoadhesive nanofibers may be a favorable mucoadhesive material for transmucosal drug delivery.
Phase Behavior of Doxycycline Hyclate-Incorporated Bleached Shellac In Situ Forming Gel/Microparticle after Solvent Movement
Authors: Senarat Setthapong , Charoenteeraboon Juree , Praphanwittaya Pitsiree , Phaechamud Thawatchai
Published: August 2020

With regard to the periodontal pocket application of in situ forming systems, the understanding the phase behavior after solidification owing to solvent movement could verify the deformability of specimen and its capacity to reside in the artificial periodontal pocket. The aim of this research was to investigate the phase behavior by determining mechanical properties as hardness and elasticity/plasticity ratio with texture analyzer for matrices obtained from drug-free and doxycycline hyclate (DX)-incorporated bleached shellac (BS) in situ forming gel (isg) and –microparticle (ism) after solvent exchange. The solvents for dissolving BS were 2-pyrrolidone (PYR), N-methyl pyrrolidone (NMP) and dimethyl sulfoxide (DMSO). The matrix from isg was less rough and bulge than that of isg. The order of mechanical hardness of transformed system prepared with different solvents was presented as PYR > NMP > DMSO, influenced by phase separation rate and porosity. The systems prepared with NMP and DMSO were more likely plastic or able to adapt its geometry to dynamic changes while that prepared with PYR was elastic. DX-incorporated ism matrix was still governed by the oil in external phase; thus, its consequence was reasonably plastic instead. XRD pattern indicated that the solvent type had no effect on the crystallinity of remained BS after solvent movement. SEM topography revealed sponge-like structure of isg prepared with DMSO and NMP whereas that prepared with PYR exhibited only initiated diminutive pores. The size and density of pores increased by time of isg using different solvents as following DMSO > NMP > PYR, whereas ism matrices had less pore density. The level of porosity of each matrix reflected the mechanical strength that a higher porous structure collapsed easily but a dense matrix considerably resisted to a compression.
Preparation and Evaluation of 6-Maleimidohexanoic Acid Grafted Chitosan Nanoparticles as a Novel Carrier for Intranasal Protein Delivery
Authors: Dumkliang Ekachai , Ngawhirunpat Tanasait , Rojanarata Theerasak , Patrojanasophon Prasopchai , Pamornpathomkul Boonnada , Opanasopit Praneet
Published: August 2020

In this study, 6-maleimidohexanoic acid grafted chitosan nanoparticles (MHA-CS NPs) were prepared and evaluated the efficiency of intranasal protein delivery as compared with well-known chitosan nanoparticles (CS NPs). Fluorescein isothiocyanate labelled with bovine serum albumin (FITC-BSA) was used as a model protein. The results indicated that both CS NPs and MHA-CS NPs were positively charged NPs before and after protein loading. The condition for optimal protein loading was 1:6 mass ratio of protein/NPs at 1 h incubation period. The optimal formulations of CS NPs and MHA-CS NPs were evaluated on porcine mucosa as ex vivo. The mucoadhesive and permeation properties of FITC-BSA loaded MHA-CS NPs showed a greater than FITC-BSA loaded CS NPs and FITC-BSA solution, respectively. These ex vivo studies present the potential of MHA-CS NPs as a novel carrier for intranasal protein delivery that will be a candidate for in vivo study.
Electrospinning of Eudragit RS100 for Nerve Tissue Engineering Scaffold
Authors: Charernsriwilaiwat Natthan , Chareonying Thapakorn , Opanasopit Praneet
Published: August 2020

Electrospinning technique is widely investigated in medical applications such as tissue engineering scaffolds, wound dressing and drug delivery. In this study, the aligned nanofiber scaffold of Eudragit RS100 was successfully fabricated via electrospinning technique for nerve tissue engineering scaffold. The diameter distribution and degree of alignment of Eudragit RS100 nanofiber scaffold were observed by scanning electron microspore (SEM). The chemical and crystalline structure of Eudragit RS100 nanofiber scaffold were analyzed using Fourier transform infrared spectroscopy (FTIR) and Powder X-ray diffactometer (PXRD). Cell culture studies using rat Schwann cells were determined to evaluate cell proliferation cell alignment and morphology. The results implied that the diameter of fiber was in the nanometer region. The Eudragit RS100 nanofiber scaffold were in an amorphous form and its chemical structure was not destructive after the electrospinning process. The Eudragit RS100 nanofiber scaffold showed biocompatibility with rat Schwann cells and growing parallel to the aligned fibers. In conclusion, the Eudragit RS100 nanofiber scaffold may have the ability to apply to nerve tissue engineering scaffold.
Validation of UV-Vis Spectrophotometric Method for Stability Evaluation of 5% Extemporaneous Vancomycin Eye Drops in Various Vehicles
Authors: Panchapornpon Danuch , Pengon Sirikarn , Chinatangkul Nawinda , Chevadisaikul Terachart
Published: August 2020

UV-Vis spectrophotometric method was validated for the stability assessment of 5% extemporaneous vancomycin eye drops in different vehicles. The eye drops were extemporaneously prepared by dissolving vancomycin in various vehicles, including sterile water for injection (SWI), 0.45% normal saline (0.45%NSS) and artificial tear. The solutions were stored at room temperature and in refrigerator for 30 days. The content of vancomycin was measured by UV-Vis spectrophotometer at 280 nm. UV-Vis Spectrophotometric method was validated according to ICH guideline. The results indicated that the method was precise and accurate. The calibration curve was linear with r2 = 0.9997 in the range of 40-160 μg/mL. LOD and LOQ were 3.39 and 10.26 μg/mL, respectively. The results showed that the percentage of vancomycin residual concentation in SWI and 0.45%NSS was decreased to less than 90% after storage at room temperature for 8 days, whereas the residual concentration of vancomycin in artificial tear was less than 90 % after 10 days in room temperature. Meanwhile the percentage of vancomycin residual concentation in all formulations was remarkably decreased to less than 90% after storage in refrigerator for 17 days. The physical appearance of eye drops in artificial tear remained unchanged. However the observed color of other formulations was gradually changed to yellow in day 7 at room temperature and day 17 in refrigerator. The pH values of all preparations were within the general U.S. pharmacopeia national formulation range of 2.5-4.5. In conclusion, the eye preparations of 5%w/v vancomycin in all selected vehicle were stable for 17 days in refrigerator (2-8°C).
Low Protein Natural Rubber Latex - Based Polymer Blends for Transdermal Patches of Mefenamic Acid
Authors: Suksaeree Jirapornchai , Pichayakorn Wiwat , Siripornpinyo Patsakorn , Chaiprasit Somruethai , Maneewattanapinyo Pattwat
Published: August 2020

Transdermal patches are attraction and acceptance for the patient due to avoid first-pass metabolism, easy to administer and removal, allows rapid termination of treatment if required etc. Low protein natural rubber latex (LPNRL) is a natural polymer that removed the allergic protein from fresh NRL prepared by treatment with proteolytic enzyme and centrifuging process. LPNRL is used for medical skin applications with the non-allergenic product. The objective of this research aimed to prepare the mefenamic acid – loaded transdermal patches made from LPNRL blended with either hydroxypropyl methylcellulose (HPMC) or polyvinyl alcohol (PVA), glycerin and polyvinylpyrrolidone were used as plasticizer and crystallization inhibitor, respectively. The moisture uptake and swelling ratio showed the increment value after either HPMC or PVA was blended in LPNRL because of the increment of their hydrophilicity. These patches showed the homogeneous films that observed by the researcher. The in vitro release showed a faster release rate after either HPMC or PVA was blended in LPNRL. It was concluded that mefenamic acid – loaded transdermal patches could be prepared by using LPNRL blended with either HPMC or PVA as matrix film former could provide an increased and controlled release of the drug. Moreover, it was safe to apply on the skin as did not cause irritation.
Simultaneous Determination of Gallic Acid and Quercetin in Leaf Extract of Madhuca longifolia from Myanmar by HPLC-DAD: Method Development and Validation
Authors: Thida Aye , Toyama Onoomar , Satiraphan Malai
Published: August 2020

Madhuca longifolia (J.Koenig ex L.) Macbr. belongs to the Sapotaceae family. This research work focused on the determination of gallic acid and quercetin in an aqueous leaf extract of M. longilolia. The development and validation of the analytical method using HPLC-DAD have been performed. The validated method was applied to determine both compounds in the leaves of M. longifolia. Optimized HPLC conditions were developed and validated for specificity, linearity, sensitivity, precision and accuracy. The linearity ranges and linear regression value were 3.125 to 100 μg/mL with r2=1 for gallic acid and 0.78 to 50 μg/mL with r2=0.9999 for quercetin, respectively. The LOD and LOQ were 0.24 and 0.73 μg/mL for gallic acid and 0.21 and 0.63 μg/mL for quercetin. Intra and inter-day precision were in the range of 0.18 to 1.76. The recovery percentage were 103.86% to 104.98% for gallic acid and 100.10% to 102.97% for quercetin. The concentration ranges of gallic acid and quercetin in the extracts were 207.95 to 405.79 mg/100 g and 7.31 to 20.56 mg/100 g, respectively. The developed HPLC method was considered to be accurate, precise and reliable for the determination of gallic acid and quercetin in M. longifolia aqueous leaf extract. This may be the first-time report for HPLC-DAD method development for the determination of bioactive phenolic compounds in Madhuca longifolia from Myanmar.
Surface Tension/Contact Angle Characters of Aprotic Binary Borneol-Dimethyl Sulphoxide Mixture
Authors: Lertsuphotvanit Nutdanai , Tuntarawongsa Sarun , Mahadlek Jongjan , Phaechamud Thawatchai
Published: August 2020

Borneol and dimethyl sulphoxide (DMSO) have been used as the skin penetration enhancers. Different concentrated borneol solutions in aprotic DMSO were prepared as the binary mixtures and determined their surface tension and contact angle behaviors using goniometer. Low borneol concentration minimized the surface tension and there was nearly stable contact angle for 30-70% borneol solutions. The trend contact angle value was decreased on glass slide, acrylic and LDPE whereas increasing on agarose gel and porcine tissues including buccal mucosa, gum and tongue with borneol concentration dependence. However, the borneol-DMSO binary mixture exhibited high wettability owing to its contact angle on glass surface was less than 90°. The solvent exchange between DMSO of borneol solutions and aqueous phase form agarose gel and porcine tissues including tongue, gum and buccal mucosa initiated the phase transformation from solution into matrix-like and promoted the higher contact angle with borneol concentration dependence. The understanding of surface tension and contact angle behaviors of aprotic borneol-DMSO binary mixture is useful for developing them into in situ forming gel for drug delivery such as in the oral cavity.
Characterization of Rheological Property of Mucoadhesive Polymeric Sol-Gel in the Presence of Black Ginger Kaempferia parviflora Extract
Authors: Taokaew Siriporn , Wattanaphraya Nattanich , Kriangkrai Worawut
Published: August 2020

The local drug delivery based on mucoadhesion is an effective medical treatment. The mucoadhesive property relies on the formulated gel having optimized rheology. The addition of the drug also showed a major influence towards the sol-gel transition. In this study, compositional effect of Eudragit E100® base polymer, various mucoadhesive polymers, and the black ginger extract on the rheological property of the formulated sol-gel was assessed. It was found that gelling point and gel strength could be tuned mainly based on the concentration of Eudragit E100 limited at 40% w/w due to the viscosity. At Eudragit E100 of 30% w/w, 0.5% w/w herbal extract, and 1%w/w polyvinyl alcohol, the solution reached the gel point at 286 s (tan δ=1) with the gel strength of 1 kPa (G’=G”). For all the formulated sol-gels, the rheological property became better (faster gelling point with the gel strength varying from 100-700 kPa at low strain) a simulated saliva environment.
Farewell to Professor David Yaffe – A Pillar of the Myogenesis Field
Authors: Yablonka-Reuveni Zipora , Stockdale Frank , Nudel Uri , Israeli David , Blau Helen M. , Shainberg Asher , Neuman Sara , Kessler-Icekson Gania , Meghid Krull Erica , Paterson Bruce , Saxel Fuchs Ora , Greenberg David , Sarig Rachel , Halevy Orna , Ozawa Eijiro , Katcoff Don J.
Published: August 2020

It is with great sadness that we have learned about the passing of Professor David Yaffe (1929-2020, Israel). Yehi Zichro Baruch - May his memory be a blessing. David was a man of family, science and nature. A native of Israel, David grew up in the historic years that preceded the birth of the State of Israel. He was a member of the group that established Kibbutz Revivim in the Negev desert, and in 1948 participated in Israel’s War of Independence. David and Ruth eventually joined Kibbutz Givat Brenner by Rehovot, permitting David to be both a kibbutz member and a life-long researcher at the Weizmann Institute of Science, where David received his PhD in 1959. David returned to the Institute after his postdoc at Stanford. Here, after several years of researching a number of tissues as models for studying the process of differentiation, David entered the myogenesis field and stayed with it to his last day. With his dedication to the field of myogenesis and his commitment to furthering the understanding of the People and the Land of Israel throughout the international scientific community, David organized the first ever myogenesis meeting that took place in Shoresh, Israel in 1975. This was followed by the 1980 myogenesis meeting at the same place and many more outstanding meetings, all of which brought together myogenesis, nature and scenery. Herein, through the preparation and publication of this current manuscript, we are meeting once again at a “David Yaffe myogenesis meeting". Some of us have been members of the Yaffe lab, some of us have known David as his national and international colleagues in the myology field. One of our contributors has also known (and communicates here) about David Yaffe’s earlier years as a kibbutznick in the Negev. Our collective reflections are a tribute to Professor David Yaffe. We are fortunate that the European Journal of Translational Myology has provided us with tremendous input and a platform for holding this 2020 distance meeting "Farwell to Professor David Yaffe - A Pillar of the Myogenesis Field".
Low-profile visible intraluminal support stent-assisted embolization therapy for intracranial dissecting aneurysms: A retrospective analysis of six cases
Authors: Jia-Hao Zhou , Richard Seidu A. , Jiang Ming , Yin-sheng Deng
Published: August 2020

Endovascular Embolization (EVE) of aneurysms is a very effective and efficient treatment modality. Nevertheless, a few complications have been reported after EVE of aneurysms. Our study therefore evaluated the safety and efficacy of Low-profile Visible Intraluminal Support (LVIS) stentassisted EVE for intracranial Dissecting Aneurysms (DAs). We conducted a retrospective study to identify patients with DAs who were treated with LVIS stent from July 2015 to September 2018. The DAs were categoried into ruptured and unruptured. The arteries harbouring the aneurysm were identified in all cases. LVIS device stent assisted coil EVE treatment modality was utilized to treat all the patients. Surgical safety, immediate surgery outcome, recurrence rate and imaging follow-up results of all patients were analysed. The Glasgow Outcome Scale (GOS) score of all patients where assessed during discharge. Cerebral angiography of all patients were reevaluated on scheduled visits from three months up to one year after their operations. A total of Six DA patients were identified during our analysis. Four of the cases were ruptured DAs while two cases were unruptured. The DAs originated from the Internal Carotid Artery (ICA) in two cases, while in the remaining four cases, the DAs originated from vertebral artery (VA). Stents and coils were successfully implanted in all six patients. The DAs were embolized satisfactorily and the parent arteries were patent immediately after the operations. We obsereved 5 points GOS score in four cases and 4 points in two cases. No aneurysmal recurrece, no stent collapse or displacement was obsereved in all cases during follow-ups. Our study suggests that, LVIS stent-assisted EVE is simple, safe and effective in the treatment of DAs.
Improving Vaccination Coverage in All Age Groups is a Global imperative: Our Profession Must Be Prepared
Authors: Jordan Dominique
Published: August 2020

Vaccination is a global imperative, and the pharmacy profession must be prepared. International pharmacy organizations defined the administration of medicines, vaccines, and injectable medications as a key role of our profession. Vaccines are second only to clean water in terms of their
impact on public health.
Ahil po smrti
Authors: Ritsos Janis , Isak Kres Jelena
Published: August 2020

Zelo je utrujen – kaj naj zdaj počne s slavo? – dovolj je bilo.

Dobro je spoznal sovražnike in prijatelje – domnevne prijatelje,

kajti za občudovanjem in ljubeznijo so se skrivale njihove lastne koristi,

njihove lastne sumljive sanje, pretkane in hkrati nedolžne.
Blues z rimskega zidu
Authors: Auden WH , Grošelj Nada
Published: August 2020

Nad barjem je veter in moker je zrak,

uši imam v tuniki, v nosu prehlad.

 

Z neba štropotajo nalivi dežja,

vojak sem na zidu, ne vem sploh, zakaj.

 

Po sivem kaménju se plazi megla,

dekle imam v Tungriji, jaz pa spim sam.
Public expenditure and growth: the Indian case*
Authors: Hakhu A. Bhatt , Sardoni C.
Published: August 2020

The paper deals with the relationship between public spending and growth as well as the dynamics of the ratio of public debt to GDP. The authors show that a composition of public spending that favors productive expenditures, that is, those with a direct positive effect on the economy's long-run rate of growth, can determine a situation in which the ratio of public debt to GDP is stable, even though the government runs primary deficits. We test our theoretical results by considering the Indian case. Our empirical analysis substantially supports the idea that the dynamics of the economy as well as of the public-debt ratio are contingent on having a public sector that favors productive expenditures.
Do fiscal rules decrease public investment? Evidence from European panel data
Authors: Wijsman Sebastiaan , Crombez Christophe
Published: August 2020

This paper studies the effects of fiscal rules on public investment. Economists argue that fiscal rules decrease public investment, as it is easier for governments to lower public investment than current expenditures. This paper presents an empirical assessment of the relationship between fiscal rules and public investment using European panel data covering the 1997–2016 period. In contrast to previous work, we focus on national fiscal rules and use the European Commission's Fiscal Rules Strength Index to measure the constraints imposed on public finances. This index captures 230 national fiscal rules and reflects the annual strength of fiscal rules in each European Union member state. In line with our expectations, we find that fiscal rules decrease public investment. We run some additional models in which the results are mixed.
Kilis Halk Hekimliğinde Tedavi Yöntemleri ve Uygulamaları
Authors: TARÇIN Gülsüm
Published: August 2020

Kilis ilinde halk hekimliği geçmişten günümüze halkın doktora gitmeden hastalıkları sağaltma amacı ile başvurduğu yöntemlerden oluşmaktadır. Bu çalışmada Kilis halkının hastalıkları iyileştirmek için çeşitli hastalıklara göre başvurduğu yöntemlerin neler olduğu ve nasıl uygulandığı tespit edilmiştir. Başvurulan yöntemler, büyülük işlemler ve gerçekçi (akılcı) yöntemleri içermektedir. Büyülük işlemleri içerenler yatırlar (türbeler) ve ocaklar iken, gerçekçi (akılcı) olarak nitelenen yöntemler ise ev ilaçları olarak tabir edilen bitki, mineral ya da hayvansal kaynaklıdır. Türbe inancı, Kilis’te birçok türbenin varlığıyla daha çok önem kazanırken, çeşitli hastalıkların sağaltılmasında da halk hekimliğinde önemli bir rol üstlenmektedir. Ocaklar ise kendi evlerinde bazı hastalıkları tedavi etmektedirler. Ocaklar, bu hastalıkları tedavi ederken parpı, ırvasa ve alazlama yöntemlerini kullanmaktadır. Kocakarı (ev) ilaçlarıyla yapılan ev tedavisinde ise sıklıkla zeytin bağlarından elde edilen zeytin ve zeytinyağından yararlanıldığı, bunun yanında doğada kendiliğinden yetişen zahter (kekik) ve peryavşan otunun ilaç olarak kullanımda yaygınlığı dikkat çekmektedir. Bu çalışmada veriler saha (alan) araştırması yapılarak görüşme tekniğiyle ve doküman incelemesiyle elde edilerek, Kilis halk hekimliğinde hastalıkları tedavi yöntemleri uygulamalarıyla birlikte değerlendirilmeye çalışılmıştır.
David Hare's "Stuff Happens": An Alternative Narrative of Iraq War
Authors: GÜLTEKİN Ömer Kemal
Published: August 2020

In the 20th century postmodernism has fundamentally altered the approach to the concept of history. Showing that grand narratives can be reversed by minor narratives, Jean-François Lyotard played a great role in the development of postmodernism. The purpose of this article is to analyse how the dramatic techniques used in David Hare’s play Stuff Happens in line with Lyotard’s take deconstruct grand narratives about Iraq War at the beginning of the 21st century. By manipulating verbatim theatre techniques, the play asserts that historical reality must always be perceived through a sceptical perspective. Setting the political verbatim accounts, therefore the grand narratives, with unheard minor voices/narratives, Hare, both unearths the discrepancies of political reality and stresses that every narrative is fictional. In this respect, as a postmodern text, Stuff Happens rejects construction of grand narratives by drawing attention to alternative realities and demonstrates that political grand narratives cannot be unique realities.
Representational and Processing Constraints on the Acquisition of Case and Gender
by Heritage and L2 Learners of Russian
Authors: Peirce Gina
Published: August 2020

Morphological errors are prevalent in adult second language production, particularly among learners whose first languages have less complex inflectional systems. Thus, U.S. learners of Russian can provide a testing ground for competing approaches to L2 morphological acquisition. This study utilizes the Russian Learner Corpus of Academic Writing (2017) to compare case and gender-marking error frequencies in timed versus untimed essays by advanced heritage and traditional L2 learners in Portland State University’s Russian Language Flagship program. It was predicted that higher error rates in timed compositions would support the position that advanced learners’ morphological errors reflect processing difficulties under time pressure. However, such differences did not reach significance for either heritage or L2 learners; in the latter group, error rates were higher in students’ untimed texts. These results could be interpreted as
demonstrating representational deficits in interlanguage grammar, particularly in the L2 group. However, greater complexity (words per T-unit) of the untimed essays provides an alternative explanation for the higher untimed error rate among this group. The heritage group had lower overall case and gender-marking error rates than the L2 group, suggesting heritage learners are less likely to show evidence of possible representational deficits of nominal functional features in their interlanguage grammar.
Empréstimos bancários consignados de duas ou mais instituições financeiras: uma perspectiva à luz do direito do consumidor como direito fundamental
Authors: Pinheiro Miguel Ângelo Portela
Published: August 2020

O presente artigo visa trazer luz ao fato de que a concessão de empréstimos consignados em contracheque por parte de bancos e fornecedoras de crédito sem uma verificação apurada da saúde financeira do consumidor constitui prática abusiva. Este tipo de crédito deve tomar até 30% do salário líquido e é dividido em parcelas que são descontadas diretamente no contracheque do cliente, o que pode comprometer a sua subsistência e de sua família, especialmente no contexto de superendividamento em que se encontram boa parte dos brasileiros. Esta realidade é inaceitável no âmbito da Constituição Cidadã de 1988, cujo valor central é o princípio da dignidade da pessoa humana, e do Código de Defesa do Consumidor, que foi o subsistema concebido a partir da positivação da defesa do consumidor como direito fundamental no art. 5º, XXXII. Esta previsão expressa deve-se à ligação íntima entre a dignidade da pessoa humana e a dignidade do consumidor, pois o consumo é parte indissociável da vida nos tempos atuais e se dá em uma relação naturalmente desequilibrada entre fornecedores e consumidores. Deste modo, instituições financeiras devem verificar pormenorizadamente as condições de seus clientes assumirem empréstimos consignados, sob pena de sofrerem revisão contratual na esfera judicial a fim de acomodarem os empréstimos em mais parcelas quanto forem necessárias que não ultrapassem os 30% estabelecidos pela Lei Federal nº 10.820/2003. A defesa da dignidade enquanto direito fundamental da personalidade em muito supera o direito à satisfação do crédito por parte de bancos e organizações afins.
O “auxílio aluguel” manauara (lei municipal n. 1.666/2012) e a sua relação com as desocupações coletivas
Authors: Santos Joao Paulo Marques dos
Published: August 2020

A Lei Municipal n. 1.666/2012 instituiu o auxílio aluguel destinado àquelas famílias atingidas pelos seguintes eventos naturais - (i) enchentes (ii) desmoronamentos e (iii) outras situações de risco – ou para realização de obras públicas. Recentemente, essa lei foi alvo de arguição incidental de inconstitucionalidade, tendo em vista o seu âmbito de proteção ser muito restrito, o que supostamente estaria violando o princípio da proporcionalidade, na sua modalidade de proteção insuficiente, já que não abarcavam as pessoas que, embora estivessem em situação de vulnerabilidade, foram objeto de reintegração de posse coletiva. A interpretação conferida pelo Tribunal de Justiça do Amazonas foi a de que o seu âmbito de proteção não engloba as pessoas que foram retirados de áreas de proteção ambiental, pois não compete ao Poder Judiciário ampliar um rol estipulado pelo Poder Legislativo. A metodologia utilizada no trabalho foi a de interpretação da decisão judicial proferida nos autos do Agravo Interno n.º 0000463-27.2018.8.04.0000 julgado pela Primeira Câmara Cível do Tribunal de Justiça do Amazonas, levando em consideração os princípios da dignidade da pessoa humana, do mínimo existencial, da proporcionalidade, da legalidade, do Estado de Direito etc., todos eles elencados pela Defensoria Pública e pela Procuradoria Geral do Estado. Após analisar as posições favoráveis e contrárias, concluiu que o Tribunal de Justiça do Estado do Amazonas acertou na sua decisão de não declarar inconstitucional a Lei Municipal n. 1.666/2012.
ON CONNECTED COMPONENT DISTRIBUTION OF RANDOM BLOCK-HIERARCHICAL NETWORKS USING THE AUTOMATED SYSTEM $ \textit{XRANDNET} $
Authors: Kocharyan A.G.
Published: August 2020

In the paper the result of a research done by using the automated system xRandNet is presented, which is designed and implemented for generating and analyzing the main topological properties of some hierarchical models of random networks. The research is related to the connected component distribution of random block-hierarchical networks, which are quite new objects in the random network theory.
ON A VERSION OF FIXED POINT THEOREM
Authors: Mikayelyan L.V.
Published: August 2020

In the present short note we prove a version of the classical fixed-point theorem, as well as present its application.
ON A UNIQUENESS THEOREM FOR THE FRANKLIN SYSTEM
Authors: Navasardyan K.A.
Published: August 2020

In this paper we prove that there exist a nontrivial Franklin series and a sequence $ M_n $ such that the partial sums $ S_{M_n} (x) $ of that series converge to 0 almost everywhere and $ \lambda \cdot \text{mes} \{ x : \sup\limits_{n}{\left| S_{M_n} (x) \right|} > \lambda \} \to 0 $ as $ \lambda \to +\infty $. This shows that the boundedness assumption of the ratio $ \dfrac{ M_{n+1}}{M_n} $, used for the proofs of uniqueness theorems in earlier papers, can not be omitted.
ON ALGEBRAIC EQUATION WITH COEFFICIENTS FROM THE $ \beta $-UNIFORM ALGEBRA $ C_{\beta} (\Omega) $
Authors: Kamalyan A.H. , Karakhanyan M.I.
Published: August 2020

In this work the question of algebraic closeness of $ \beta $-uniform algebra $ A (\Omega) $ defined on locally compact space $ \Omega $ is investigated.
EFFECT OF DONOR IMPURITY ON AHARONOV–BOHM OSCILLATIONS IN A DOUBLE QUANTUM RING WITH GAUSSIAN CONFINEMENT
Authors: Mughnetsyan V.N.
Published: August 2020

In this paper the effect of donor impurity on the Aharonov–Bohm oscillations of the electronic states in a double quantum ring with Gaussian confinement has been studied. Three different impurity positions: namely in the inner ring, in the outer ring and in the barrier between the rings, have been considered. It is shown that the energies of the two lowest states are almost constant, while for the higher levels the Aharonov–Bohm oscillations are observed. The obtained results indicate on the possibility of the effective control of the quantum states by means of donor impurity and external magnetic field.
STUDY OF THE SWELLING OF THE PHOSPHOLIPID BILAYER, DEPENDING ON THE ANGLE BETWEEN THE INCLINATION OF THE DIPOLE FRAGMENTS AND THE PLANE OF THE LAMELLA
Authors: Stepanyan M.A.
Published: August 2020

Using computer simulations and simultaneous X-ray diffraction at large and small angles, the dependence of the swelling coefficient of the phospholipid bilayer on the angle between the inclination of dipole fragments and the plane of the lamella was investigated. It was shown that in this case the balance between electrostatic, repulsive and van der Waals attraction forces is a particular importance. As the dipole angle increases, the repulsive forces of the electrostatic dipole-dipole interaction increase, resulting the increase of the bilayer thickness as a function of the number of –CH-groups in the phospholipid. At a certain angle the bilayer is destroyed. It is also shown that at certain small angles the bilayer takes a minimum thickness. In this case a phase transformation takes place and the system enters the “gel”-phase.
A NECESSARY AND SUFFICIENT CONDITION FOR THE UNIQUENESS OF $ \beta\delta $-NORMAL FORM OF TYPED $ \lambda $-TERMS FOR THE CANONICAL NOTION OF $ \delta $-REDUCTION
Authors: Budaghyan L.E. , Grigoryan D.A. , Torosyan L.H.
Published: August 2020

In this paper the canonical notion of $ \delta $-reduction is considered. Typed $ \lambda $-terms use variables of any order and constants of order $ \leq 1 $, where the constants of order 1 are strongly computable, monotonic functions with indeterminate values of arguments. The canonical notion of $ \delta $-reduction is the notion of $ \delta $-reduction that is used in the implementation of functional programming languages. It is shown that for canonical notion of $ \delta $-reduction SI-property is the necessary and sufficient condition for the uniqueness of $ \beta\delta $-normal form of typed $ \lambda $-terms.
QUASI-BOOLEAN POWER OF ALGEBRAS AND IDEMPOTENT ALGEBRAS
Authors: Yolchyan M.A.
Published: August 2020

In this paper we provide a necessity condition for embedding of the binary algebra into the quasi-boolean power of a rectangular algebra. It is also proved that every idempotent and hyperassociative algebra via the weak bihomomorphism maps in an idempotent and commutative algebra.
STUDY OF ELECTRONS ENERGY RESOLUTION, IN CMS (LHC) EXPERIMENT USING SIMULATED DATA
Authors: Hayrapetyan A.A.
Published: August 2020

This work is dedicated to the study of the energy resolution of electrons using simulated data of “Drell-Yan” process with \( e^{-}e^{+} \) yield in \(pp\)‑interactions at \( \sqrt{s}=13\ TeV \). The work contains a brief description of event modeling and electron reconstruction from the simulated data. The energy resolution was estimated from the distribution of the ratio of the transverse energies of reconstructed and generated electrons. Two approaches used in calculations. In the first approach, the standard definition of energy resolution was used (Full width at half maximum – FWHM), and in the second, the root mean square of distribution was taken as a describing value for energy resolution.
METHOD FOR PRECISE SYNCHRONIZATION BETWEEN MULTIPLE VECTOR SIGNAL GENERATORS
Authors: Hovhannisyan B.A. , Margaryan N.G. , Tsaturyan G.A. , Antonyan S.V. , Ohanyan G.A. , Manvelyan M.T.
Published: August 2020

An important task of modeling and testing radar systems is to synchronize the order of the sub-degree of the radiated signals between the two ports of the transmitters. The simulation of synchronization of two NI PXI 5840 vector transceivers was performed with the separation of the power of the local oscillator and the clock generator. The simulation was done in the LabVIEW software environment using the developed program.
Wanprestasi Manajer Investasi Terhadap Investor Reksadana
Authors: Pariela Marselo Valentino Geovani
Published: August 2020

The Investment Manager is the party managing Mutual Funds either in the form of the Company or in the form of Collective Investment Contract, one of Mutual Fund products is Mutual Fund Shares. Investment Managers in managing Mutual Funds perform securities portfolio activities as well as collective investment portfolios. Portfolio is intended to minimize the risks that occur when managing the investment, with the portfolio, expected returns that expected investors can be reached maximally in the management of mutual funds Shares never escape the error. Such an Investment Manager's mistake may cause a loss on the part of the investor
Tanggung Gugat Resiko Dalam Aspek Hukum Kesehatan
Authors: Anwar Arman
Published: August 2020

Health is a fundamental need for every human being in his life and to meet these needs the role of doctors and health workers is very important. Doctors and Health care in providing health services to the community is always required in order to provide the best service. So with the Hospital. However, the health services provided may result in two different possibilities of the patient being cured or even worsening the disease until death. If the patient recovers it will flow millions of praise and abundant various forms of appreciation that he receives but if that happens is the opposite then in certain conditions where the patient feels aggrieved can culminate until the lawsuit to court. In medical practice, doctors do not work alone but are also often assisted by other health workers. Likewise Hospital as a corporation employs doctors and health workers to provide health services to the community. If in the event of any medical treatment from medical personnel to medical personnel and/or Hospital to the physician and at risk of mistake or negligence in the health service, then the loss suffered by the patient may result in risks (risico aanspraklijkheid) based on Article 1367 paragraph (3) BW. In the context of health law regulated in Article 65 of Law Number 36 Year 2014 on Health Personnel, and Article 35 Paragraph 6 of Law Number 38 Year 2014 on Nursing and Article 23 Paragraph (3) point c Regulation of the Minister of Health of the Republic of Indonesia No. 2052 / Menkes / Per / X / 2011 About Practice License and Implementation of Medical Practice as well as Article 46 Act Number 44 of 2009 About Hospital that is Hospital is legally responsible for all the losses caused by negligence made by health personnel in the Hospital. Efforts to prevent it internally need to agree on the rights and obligations of each party in a specified standard of conduct that is proportionally regulated and based on equitability values, either in the form of Hospital by Law as well as the prevailing rules binding on all staff within a hospital staff (Medical staff by law).
Penetapan Status Tersangka Dan Terdakwa Calon Kepala Daerah Dan Implikasi Yuridisnya Dalam Pemilihan Kepala Daerah (Kajian Yuridis Normatif)
Authors: Ropii Imam
Published: August 2020

Political contestation in the election of regional heads simultaneously in the third stage of 2017 became popular in particular the election of regional heads in Jakarta Special Capital Region (DKI). The popularity of DKI Regional Head election is because one of the candidates of the regional head (petahana candidate) is currently a suspect status and has even increased to be the defendant for allegedly doing the act of defamation of religion. The juridical of the candidate for the head of a suspect or defendant has no effect on the nomination process in the election. Couple of candidates with such status will continue to follow the election stage to complete. If in the Pilkada the suspect's partner or the defendant wins, the convicted person will be dismissed and subsequently replaced as stipulated in the legislation.
Current status of transcatheter closure of patent foramen ovale
Authors: Palacios Igor F.
Published: August 2020

A patent foramen ovale (PFO) is a highly prevalent structure among the adult population. It allows the shunt of blood through the inter-atrial septum and has been associated with cryptogenic stroke, transient ischemic attack, significant right to left shunting resulting in resting and exercise-induced hypoxemia, platypnea orthodeoxia syndrome, and decompression sickness after scuba diving and migraines. Currently, transthoracic and transesophageal echocardiography and transcranial Doppler are the most important diagnostic tools, for the diagnosis of PFO. The sensitivity and specificity of the study depend on the modalities available: transthoracic (TTE), transesophageal (TEE), and transcranial Doppler (TCD), as well as the intravenous use of agitated saline and the site of injection.
The A54T polymorphism in the FABP2 gene and its relationship with obesity
Authors: Torres Maritza , Prieto Carem , Ortiz Rina , Siguencia Wilson , Durán Pablo , Pérez José , Díaz María P. , Rojas Milagros , Chacin Maricarmen , Cano Clímaco , Bermúdez Valmore
Published: August 2020

Introducción: La obesidad es una enfermedad compleja, multifactorial y en su mayor parte prevenible que afecta, a más de un tercio de la población mundial actual. Las variaciones en la secuencia de nucleótidos de los genes de control del metabolismo y del apetito se consideran hasta ahora como factores no modificables y se asocian con alteraciones del IMC, del perfil lipídico y de la circunferencia abdominal. Métodos: Se realizó una investigación analítica, no experimental y transversal con el propósito de evaluar la presencia del polimorfismo A54T en el gen FABP en una submuestra del Estudio de Prevalencia del Síndrome Metabólico de la Ciudad de Maracaibo. Resultados: De los 154 individuos de la submuestra ocho sujetos fueron portadores del polimorfismo A54T, es decir, una frecuencia genotípica de 5,19 %, con una distribución por sexo de 50 % para las mujeres (n=4) y 50 % (n=4) para los hombres. Con respecto al grado de similitud de los alelos, el 75 % (n=6) eran homocigotos y el 25 % (n=2) heterocigotos. El diagnóstico de obesidad a lo largo del IMC sólo estuvo presente en el 12,50 % (n=1) de los portadores de A54T. Por el contrario, el 25 % (n=2) de los portadores tenían sobrepeso; el 50 % (n=4) se presentaron como personas de peso normal; y sólo el 12,50 % (n=1) en la categoría de peso insuficiente. Conclusión: No se encontró una asociación entre el polimorfismo de Ala54Thr y la obesidad. Este resultado refuerza el carácter multifactorial de estas enfermedades y que un estado portador de este polimorfismo no es causa necesaria para padecer obesidad, al menos, en nuestro medio.
The Factors Underpricing Level in The Companies Conducting Initial Public Offering At Indonesia Stock Exchange
Authors: Rabiqy Yohandes , Yusnaidi Yusnaidi
Published: August 2020

The purpose of this research is to examine and analyze the influence of of the variables Current Ratio, Firm Size, Financial Leverage, and Return on Equity to Underpricing level. This research used the Initial Public Offerings companies which was listed its stock to Indonesian Stock Exchange. The data that is used at this research was taken from the annual published financial report of each company. The population in this research is companies that were listed to Indonesian Stock Exchange during period 2012 through 2016. The amount of population was 115 companies. Based on certain criteria, there are 62 samples from population. Method of multiple linear regressions on panel data approach using Common Effect Model (The Pooled Least Square). Simultaneous test in hypotesis results shows that Current Ratio, Firm Size, Financial Leverage, and Return on Equity have a significant effect on the Underpricing level of Initial Public Offerings companies. Partial test (t-test) in hypothesis result shows that Firm Size have a negative and significant effect on the Underpricing level of Initial Public Offerings companies that listed in Indonesian Stock Exchange. Current Ratio, Financial Leverage, and Return on Equity have a negatif and insignificant on the Underpricing level of Initial Public Offerings companies that listed in Indonesian Stock Exchange.

Keywords: Common Effect Model, Financial Leverage, Firm Size, Return on Equity, Underpricing Current Ratio
Mediating Effect of Capital Expenditure on the Effect of Revenues, Allocation Fund, and Tax/Nontax Sharing on Economic Growth (Empirical Study of Regencies in Bengkulu Province Period of 2009-2015)
Authors: Elsivera Elsivera , Abdillah Willy
Published: August 2020

This research examines the mediating effect of capital expenditure on the relationship between regional revenues (PAD), general allocation fund (DAU), specific allocation fund (DAK), and tax sharing fund/non tax sharing (DBH) on the economic growth. Secondary data were collected from 10 regencies in Bengkulu Province for the period of 2009 to 2015. This research used panel data analysis. The results showed that capital expenditure did not mediate the relationship between regional generated revenues, general allocation fund, specific allocation fund, and tax sharing fund/non tax sharing to economic growth. Meanwhile, general allocation fund have positif effect on economic growth. Regional generated revenues and specific allocation fund have negative effect on economic growth, regional revenues and specific allocation fund also have positive effect on capital expenditure. Implication for stakeholders and further research are discussed.
Keywords: Capital Expenditure, Economic Growth, General Allocation Fund, Regional Generated Revenues, , Specific Allocation Fund, Tax Sharing Fund /Non Tax Sharing