bluuebunny/crossref_metadata_2025 huggingface dataset:
The Features of German Political-Military Penetration to Africa during the End of the 20th — 21th Centuries
Authors: Trunov Philipp
Published: July 2024

The article explores the forms and geographical features of usage in the political context by the Second and Third Reich of military tools in Africa. The scientific paper considers the historic determination of creation of lasting strategic positions in Africa for the success of German gaining the status of world power. The goal of the article is to explore the character, distinctive features and the results of German political-military presence ensuring in Africa during the period of 1990s — 2010s. The methodical basis of the paper is the concept of the “regional circles”. The author reveals the content and results of three German attempts to take participation in the solution of “Somalian problem”. In comparison with this experience the article shows the evolution of German approach to the usage of political-diplomatic and military tools in the process of Mali armed conflict resolution. The scientific paper shows its importance for the development of cooperation with other Sahel states and countries in North Africa. In this regard special attention is paid to the bilateral cooperation with Algeria and Egypt in political-military sphere, including the attempts of “Libyan question” resolution.
Experience in Regulating Lobbying in Federal Republic of Germany
Authors: Borisova Katerina
Published: July 2024

In today's realities, the Russian economy is subjected to serious tests, including the extremely strong sanctions pressure on Russian business. In this connection, despite the protectionist measures taken by the leadership of our country, the contradictions between business and government are intensifying. The aggravation of these relations puts the Russian business community before the need to find compromise solutions and legitimate ways to defend its interests in the government structures. The experience of the Federal Republic of Germany seems extremely attractive in this sense. The article analyzes the legal regulation of lobbying activities in Federal Republic of Germany. The purpose of the article is to reveal the main models of legal regulation of lobbying activities on the example of German, to identify their positive and negative sides. The author's position on lobbying the interests of various social groups as a component of effective political system, which allows finding a compromise in society, is substantiated.
Comecon Internal Assessment of the Oil Market Conditions on the Eve of the 1973—1974 Oil Shock
Authors: Glazov Alexandr
Published: July 2024

Today, in the context of the fourth energy transition and the simultaneous increase of problems in the global fuel and energy complex, it is important for humanity to take into account all the experience accumulated by it to date, including negative experience, when composing and implementing various development plans / economic projects. In particular, it is necessary to avoid repeating the mistakes that were associated with the beginning and serious consequences of the 1970s energy crisis. This article attempts to reveal Comecon internal assessment of the oil market conditions on the eve of the 1973—1974 oil shock. The author of the article for the first time publishes and introduces into scientific circulation an analytical document prepared in the mid-1973 by Soviet specialists for Comecon Oil Bureau “The situation in the capitalist oil market in 1972 — the first half of 1973 and the prospects for its development”, on the basis of which interested Comecon member states worked out a common short-term strategy for the purchase of petroleum outside “the world system of socialism”. The published document confirms Comecon good awareness (in general but not always in detail) of what was happening to the oil and gas industry of capitalist countries in the seventies. The archeographic processing of “The situation in the capitalist oil market in 1972 — the first half of 1973 and the prospects for its development” was carried out in accordance with the generally accepted rules for the publication of historical documents.
Scientific Policy of Nazi Germany and Coordination of the Prussian Academy of Sciences
Authors: Khryakov Alexander
Published: July 2024

The article is devoted to the consideration of the scientific policy of Germany in the 1930—1940s. The possible reasons for historians' long-term disregard of this problem are analyzed, related both to the reluctance of the researchers themselves and the peculiarities of the perception of science by the leaders of the German state. Special attention is paid to the activities of the Ministry of Science, Education and Public Education. The example of the Prussian Academy of Sciences (Berlin) shows the specifics of the National Socialist coordination of scientific organizations and the competition between numerous departments for control over the oldest scientific organization in Germany.
The Phenomenon of Time in the Context of Urban History: the Long Middle Ages and Its Legacy
Authors: Kirillova Ekaterina
Published: July 2024

A wide range of problems related to the study of the phenomenon of time, which flows in a special way in the urban environment and organizes the life of citizens, was presented at the All-Russian Scientific Conference “Time in the city: the long Middle Ages and its legacy”, held on September 19—20, 2022, in Moscow, organized by the Institute of World History of the Russian Academy of Sciences. At the conference, reports were made summarizing the experience of studying time in a medieval city, its calculation and regulation, as well as the perception of the historical past of the city in the Middle Ages and at the present time.
Fibonacci and Lucas numbers of the form -2^a-3^b-5^c+7^d
Authors: Ibarra Sofía , Rivera Luis Manuel
Published: July 2024

In this note we find all Fibonacci and Lucas numbers of the form -2^a-3^b-5^c+7^d where a, b, c, d are non-negative integers, with 0 ≤ max{a, b, c} ≤ d. This result gives an answer to a question posed by Qu, Zeng and Cao.
Response of microencapsulated Lactobacillus casei to in-vitro conditions that simulate the gastrointestinal environment and inhibitory potential on Staphylococcus aureus
Authors: Cerón-Córdoba Jhon Fredy , Bolaños-Bolaños Juan Carlos , Jurado-Gámez Henry
Published: July 2024

Introduction: from a microbiological point of view, Staphylococcus aureus is one of the main contaminants causing foodborne illnesses, with symptoms such as nausea, vomiting, diarrhea, abdominal cramps, joint or back pain and fatigue. Bacterial resistance of pathogenic bacteria has recently been found to be a public health problem. An alternative is the use of microencapsulated probiotics for the inhibition of pathogenic microorganisms such as Lactobacillus casei. Objective: evaluate microencapsulated Lactobacillus casei ATCC 393® under in-vitro conditions simulating the gastrointestinal environment and the inhibitory potential on Staphylococcus aureus ATCC BAA 1708®. Materials and methods: reconstitution, seeding and adjustment of the inoculum; antibiogram of the two bacterial strains; fermentation kinetics of Lactobacillus casei; identification of peptides, amino acids and lactic acid of the supernatant; resistance of Lactobacillus casei to different temperatures (37 °C and 45 °C); microencapsulation of Lactobacillus casei; study, characterization and exposure to simulated gastrointestinal conditions of the microencapsulate after 90 days of storage and production of Exopolysaccharides. Results: the results indicate inhibitory action of the Lactobacillus casei strain against pathogenic bacteria; exponential phase at 15 hours (MRS culture medium) and 18 hours (PRO culture medium); results of the microencapsulation study and analysis: viability 100 %; efficiency 84,64 %; humidity 4,0 %; solubility 99,8 %; wettability 2 min with 22 seconds; water activity 0,617 and particle size between 2,10 µm and 5,28 µm. Conclusion: it was concluded that the microencapsulated Lactobacillus casei showed inhibitory properties against the pathogenic strain.
Prevalencia de lesiones de alto grado en cérvix y factores epidemiológicos relacionados en mujeres menores de 30 años, en un hospital de Popayán, Cauca, 2010-2020
Authors: Patiño-Muñoz Ángela María , Ortiz-Martínez Roberth Alirio , Acosta-Aragón María Piedad
Published: July 2024

Introducción: el diagnóstico y tratamiento oportuno de las lesiones cervicales de alto grado es crucial para prevenir su progresión hacia cáncer. En Colombia, el cáncer de cérvix ocupa el cuarto lugar en incidencia, y a pesar de la implementación de medidas de prevención como la vacunación, la incidencia continúa siendo alta, incluso en mujeres menores de 30 años. Objetivo: determinar la prevalencia de lesiones cervicales de alto grado en mujeres de 30 años o menos que acudieron a un hospital de Popayán entre 2010 y 2020, y los factores epidemiológicos relacionados con estas lesiones. Materiales y métodos: estudio transversal; se incluyeron a todas las mujeres menores de 30 años que contaban con estudio citológico, colposcópico y reporte de biopsia. Se diseñó un formulario para recopilar la información de las historias clínicas. Resultados: de las 701 mujeres incluidas, el 12,27 % presentaba lesiones de alto grado en la histopatología. Al analizar los factores de riesgo, se observó que aproximadamente el 33 % de la muestra había iniciado relaciones sexuales a los 14 años, y el 69 % reportó haber tenido más de 3 compañeros sexuales. Conclusión: la detección de lesiones de alto grado en una citología indica una mayor probabilidad de confirmar la presencia de estas lesiones en estudios adicionales, como la colposcopia o biopsia. Sin embargo, una citología negativa no descarta la existencia de lesiones cervicales.
Recurrencia de Pancreatitis Inducida por metformina: reporte de un caso
Authors: Aragón-Guzmán Diana Marcela , Salazar-Solarte Aura María , Rivera-Martinez Wilfredo Antonio
Published: July 2024

La Pancreatitis Aguda es un efecto secundario inusual de la metformina. Se presenta el caso de una mujer de 29 años con antecedentes de Pancreatitis Aguda Necrotizante Baltazar D en 2020. En marzo de 2021, presenta nuevamente pancreatitis aguda, esta vez clasificada como Baltazar C, sin necrosis evidente. Las investigaciones no revelaron causas habituales, pero se destacó que, en las dos semanas previas a ambos episodios, la paciente había recibido tratamiento con metformina para el síndrome de Ovario Poliquístico y Prediabetes, respectivamente. La respuesta exitosa incluyó la administración de líquidos intravenosos y la suspensión del medicamento, lo cual evitó complicaciones inmediatas y logró una reversión completa de los síntomas. En casos similares, es crucial identificar factores de riesgo, ajustar la dosis según la función renal y realizar una vigilancia estrecha ante cualquier sintomatología asociada con la Pancreatitis Aguda.
Influence of atmospheric wind on the propagation of radio waves
Authors: Klyuev Dmitriy S. , Volobuev Andrey N. , Adyshirin-Zade Kaira A. , Antipova Tatyana A. , Aleksandrova Natalia N.
Published: July 2024

Background. It is necessary to study the influence of the physical characteristics of the atmosphere, in particular, wind on atmospheric turbulence and, consequently, on the characteristics of the radio signal it is shown.
Aim. The dependence of the time-spectral function of the radio signal energy flux on the wind speed in the troposphere in the antenna plane is found.
Methods. A method of transition from the Cartesian coordinate system in the antenna plane to the polar coordinate system of wave numbers has been developed. Based on this method the relationship between the Fourier spectral function of the correlation moment and the representation of the Bessel function is found. For the Fourier spectral function of the correlation moment, the previously obtained solution of the differential equation for the fluctuations of the eikonal amplitude of electromagnetic wave in a turbulent atmosphere at the front of the electromagnetic wave at the coordinate of the receiving antenna is used. Using the inverse Fourier transform the relationship between the time-spectral function of the radio signal energy flux and the time-correlation function of this flux is found.
Results. Based on the study of the time-correlation function of the radio signal energy flow its relationship with the two-point correlation moment characterizing the fluctuations of the eikonal amplitude of the radio signal is found. To analyze the effect of wind, a turbulence model was used, reflecting the inertial turbulence interval, in which the energy flow from larger turbulent vortices to smaller vortices is determined by the viscous dissipation of the smallest vortices. Conclusion. Numerical calculations have shown that such a wind in the antenna plane blows away turbulent vortices in this plane, bettering the quality of the received radio signal.
Formation of a panoramic image of the inner surface of the pipe
Authors: Loshkarev Alexey S.
Published: July 2024

Background. Visual non-destructive testing of the inner surface of pipes is an important aspect in their production and operation. A defect detected and corrected in a timely manner can significantly reduce the number of defects in production and prevent various emergency incidents during operation. Formation of a complete panoramic image of the inner surface of pipes suitable for quality analysis is an urgent and sought-after task that can be solved using computer vision systems.
Aim. This work is the research and development of television methods for forming a complete panoramic image of the inner surface of a pipe, which can be analyzed to search for defects.
Methods. To form a cylindrical panoramic image, mathematical models for the formation of an equidistant projection of spherical images obtained using a fisheye lens were used. For high-quality stitching of the resulting frames, digital image processing methods were used, including brightness and contrast transformations, and searching for special points using the MSER algorithm. Theoretical results are verified by full-scale modeling.
Results. The result of this work is an algorithm for stitching frames of a video sequence generated by a television camera with a fisheye optical system, uniformly moved along the longitudinal axis of the pipe, into a single panoramic image of the internal surface. Conclusion. The algorithm ensures the formation of a high-quality image of a full panorama of the inner surface of the pipes with the absence of brightness artifacts.
Data Integration and Data Engineering Techniques
Authors: Mandala Vishwanadham
Published: July 2024

Data integration and data engineering techniques play a crucial role in the modern data landscape, facilitating the seamless amalgamation of diverse data sources to derive meaningful insights. As organizations increasingly rely on big data analytics, the need for efficient and robust data integration methodologies becomes paramount. This paper explores various techniques for data integration, including Extract, Transform, Load (ETL), data virtualization, and data federation, emphasizing their applicability across different domains. Additionally, we discuss data engineering practices that ensure the quality, scalability, and accessibility of integrated data, such as data modeling, pipeline architecture, and real-time data processing. By examining case studies and emerging trends, this work highlights the significance of these techniques in enabling organizations to harness the full potential of their data, ultimately driving informed decision-making and fostering innovation in an increasingly data-driven world.
An Overview of Data Science Algorithms
Authors: Mandala Vishwanadham
Published: July 2024

Data science algorithms are on the way to becoming an integral part of every company, and we can already see the effects in many corporations that have invented their own data science teams and also implemented the latest data science algorithms. To be able to work with all the different challenges that are emerging, new powerful data science tools have been developed (e.g. Python, R, H2O, Weka, Tensorflow, Spark, Flink, BigML or KNIME). One balance that companies that want to use these new tools have to face is the cost of implementation vs. the enhanced development that they give in return. Nowadays, most of the advanced algorithms are open source and available on multiple platforms and programming languages, which helps to minimize the development cost challenges that each company has to overcome.
Still, one of the main dangers lurking inside these development teams is that they do not know what the state of the art of advanced algorithms is and which problem they can address. To help mitigate this problem, a review of algorithms has been implemented in this paper. This review gives us a perspective on which algorithms are being developed and which problem areas they can address. With the development of more powerful data science algorithms, we are also enabling the possibility of tackling more complex and interesting problems. However, one characteristic of the review is that there are missing algorithms from the many that are currently being produced and frequently selected by the community as the best performers in many benchmark datasets.
Leveraging Image Analysis for High-throughput Phenotyping of Legume Plants
Authors: Kim Bong-Hyun
Published: July 2024

Background: The advancements achieved in artificial intelligence (AI) technology in recent decades have not yet been equaled by agricultural phenotyping approaches that are both rapid and precise. Efficient crop phenotyping technologies are necessary to enhance crop improvement endeavors in order to fulfill the projected demand for food in future. Methods: This work demonstrates a method for non-destructive physiological state phenotyping of plants using cutting-edge image processing methods in conjunction with chlorophyll fluorescence imaging. Key fluorescence metrics, such as fv/fm and NPQ, were extracted from images taken at different phases of development via processing. In addition, this research explores the transformative role of automated image analysis in high-throughput phenotyping of legume traits. A comprehensive examination of recent studies reveals the diverse applications of machine learning and deep learning algorithms in capturing morphological traits, assessing physiological parameters, detecting stress and diseases in various legume species. The comparative analysis underscores the superiority of automated systems over traditional methods, emphasizing scalability and efficiency. Challenges, including algorithm sensitivity and environmental variability, are identified, urging further refinement. Recommendations advocate for standardized metrics, interdisciplinary collaborations and user-friendly platforms to enhance accessibility. As the field evolves, the integration of automated image analysis holds promise for revolutionizing legume phenotyping, accelerating crop improvement and contributing to global food security in sustainable agriculture. Result: The findings demonstrate that the proposed method is effective in illuminating how plants respond to their environment, hence promoting advancements in plant phenotyping and agricultural research.
Tratamento de resíduos químicos gerados em laboratórios de ensino que contém íons prata e cromo
Authors: Assunção Jeysla Albuquerque , Neto Diógenes de Sousa , Lins Renata Ferreira
Published: July 2024

Considerando a importância de tratamento de resíduos químicos obtidos nos laboratórios de química da Universidade Federal do Norte do Tocantins (UFNT) e tendo em vista reduzir a quantidade de resíduos armazenados nos laboratórios do Campus Araguaína e seu impacto ao meio ambiente, este trabalho tem como objetivo realizar o tratamento de resíduos contendo íons prata e cromo nos laboratórios do curso de Licenciatura em Química da UFNT . Essas ações visam desenvolver medidas de tratamento e minimização viáveis economicamente e ambientalmente. Para realizar o tratamento dos resíduos contendo íons de prata e cromo foram utilizadas metodologias propostas na literatura. Primeiramente separou-se o sobrenadante do precipitado por filtração simples e em seguida, o precipitado foi seco em estufa e armazenado para posterior tratamento e obetenção de sais de prata. O sobrenadante foi tratado com tiossulfato de sódio (Na2S2O3) e hidróxido de sódio para formação de composto de cromo. .A partir do tratamento dos resíduos obteve-se   cloreto de prata e hidróxido de cromo reduzindo consideravelmente o volume destes rejeitos em laboratório.
Palavras-chaves: Tratamento Químico, Cromo, Prata, Sustentabilidade
Biotechnological potential of the endophytic fungi isolated from Clitoria guianensis
Authors: Ferraz Luana Fernandes , Miranda Luiz Renato Lima Silva , Moraes Gleys Kellen Aquino , Chagas Junior Aloísio Freitas , Chapla Vanessa Mara
Published: July 2024

The biodiversity of endophytic fungi in the Cerrado region in the north of Brazil remains largely unexplored, however it is important to explore the biotechnological potential of these endophytes. In this study, we isolated seventeen endophytic fungi strains from the medicinal plant Clitoria guianensis and tested the ability of these strain to inhibit the phytopathogenic fungi: Fusarium oxysporum, Bipolaris oryzae, and Curvularia lunata. The in vitro antagonistic assay was evaluated on different time scales (six and twelve days), we observed that all strains of endophytic fungi, isolated from C. guianenses, inhibited the growth of F. oxysporum and B. oryzae after six days, for C. lunata just ten strains inhibited its growth in the first six days. In twelve days, only the strains CGF1, CGF3, and CGF4 inhibited the growth of F. oxysporum, while for the other phytopathogenic fungi the inhibitions were not observed. The endophytic fungi were cultivated in a controlled environment using potato dextrose broth (PDB) medium and the crude extracts were obtained by extracting the fungi culture with ethyl acetate (EtOAc). All the crude extracts exhibited antioxidant activity, as assessed by the 2,2 diphenyl-1-picrylhydrazyl (DPPH) method. Additionally, four different concentrations (C100, C500, C1000 and C2000) of the crude extracts were evaluated in the in vitro allelopathic assay using Lactuca sativa (lettuce) seeds. Some fungal extracts demonstrated allelopathic effects by inhibiting the growth of Lactuca sativa seedlings, for example, the crude extract obtained from the strain CGF7 at a concentration of C2000 inhibited radicle development by 75.2%. While others acted as growth promoters, as is the case with the crude extract of the CGF10 strain, which contributed to lettuce radicle growth by 15.9% in C2000. Overall, these findings suggest that endophytic fungi associated with C. guianensis have significant biotechnological potential and can be used as biocontrol agents against phytopathogens and specific plants, in addition to growth promoters, making them valuable tools for sustainable agriculture.
Prospecção fitoquímica de duas espécies vegetais de Piperaceae no Sul do Amazonas, Brasil
Authors: Silva Carmen Malafaia , Souza Doraci Brito de , Silva Fernanda Mota da , Nascimento Joel Guerreiro , Gomes José Martins , Barbosa Manuel Saldanha , Nina Matheus Mendes , Cruz Priscila Beleza , Lima Rafaela Silva de , Lima Renato Abreu
Published: July 2024

O gênero Piper, pertencente à família Piperaceae representa cerca de 700 espécies, com dimensão em diferentes habitats, sendo em grande parte expostas em áreas úmidas, em áreas desmatadas e em florestas. A partir desta abordagem, o trabalho teve como objetivo identificar os metabólitos secundários do extrato etanólico das espécies Piper aduncum L., e Piper tuberculatum Jacq. O seguinte estudo foi realizado por três etapas: coleta do material botânico e herborização, extração e estudo fitoquímico. A coleta botânica foi realizada no IEAA/UFAM, e em seguida foi realizado o processo de herborização que consistiu na prensagem, secagem e montagem das exsicatas, o segundo processo foi feito a extração metanólica das partes aéreas (folhas e talos) das espécies vegetais e por fim a prospecção fitoquímica. Para P. aduncum, observou-se a presença de alcalóides, flavonóides, glicosídeos cardiotônicos, triterpenos, cumarinas e saponinas e ausência para taninos. Enquanto para P. tuberculatum observou-se a presença de alcalóides, flavonóides, glicosídeos cardiotônicos, e saponinas e ausência para taninos, cumarinas e triterpenos. Nesta perspectiva, conhecer que metabólitos estão presentes nas plantas, seja de origem primária ou secundária, torna-se importante para a produção de novos medicamentos com terapêutica eficaz e acessível. Portanto, a análise dos metabólitos secundários nos extratos etanólicos analisados oferecem percepções valiosas sobre suas propriedades químicas e biológicas. No entanto, é essencial continuar a pesquisa para validar essas descobertas e explorar completamente as aplicações práticas desses compostos.
NEUROVISUALIZATION OF NEUROVASCULAR CONFLICT
Authors:   Tashkent State Dental Institute, ABDULLAYEVA MUBORAK B. , INOYATOVA SITORA O. ,   Tashkent State Dental Institute, YODGOROVA UMIDA G. ,   Tashkent State Dental Institute, HIKMATULLAEVA SHAKHNOZA SH. ,   Tashkent State Dental Institute, YADGAROVA LOLA B. ,   Tashkent State Dental Institute, DADAZHONOV ZIYOVIDDIN A. ,   Tashkent State Dental Institute
Published: July 2024

Introduction. According to the World Health Organization, the annual incidence of new cases of trigeminal neuralgia is 3 to 5 per 100,000 people. Views on the pathogenesis of classical trigeminal neuralgia changed significantly after Peter Jannetta had published his own results of the microvascular decompression of this condition. This was preceded by some publications dealing with the anatomical features of the trigeminal nerve relationship with the arterial vessels of the cerebellum. To diagnose neurovascular conflict in patients with classic trigeminal neuralgia, magnetic resonance imaging is widely used in vascular mode with 3D volumetric image reconstruction. Despite specific magnetic resonance imaging descriptions, the neurovascular conflict site is not always visible. The results of surgical treatment show that pain disappears immediately after microvascular decompression surgery. Since myelin cannot regenerate within a few hours, other factors may explain this rapid therapeutic effect and require further study. Aim. Comparison of data obtained using magnetic resonance imaging and computed tomography angiography to visualize neurovascular conflict to assess the imaging quality. Materials and Methods. 315 patients (202 women, 113 men, mean age 55.06±15.49 years) with suspected neurovascular conflict were examined. All patients underwent the computed tomography and magnetic resonance imaging of the brain to confirm a neurovascular conflict. Results and Discussion. Visualization of the neurovascular conflict on magnetic resonance imaging was more detailed and clearer as compared with the results of spiral computed tomography angiography, providing better anatomical resolution, including clearer differentiation of vascular structures and nerves, and small vascular branches. In a magnetic resonance imaging study, some patients were found to have more severe trigeminal nerve compression as compared to the findings of spiral computed tomography angiography. Conclusion. In summary, magnetic resonance imaging in different modes helps localize neurovascular conflict in patients with trigeminal neuralgia. Its presence in combination with standard assessment increases magnetic resonance imaging sensitivity up to more than 89% without increasing the risk of harm to patients or causing any additional costs.
DYNAMICS OF AND TRENDS IN THE INCIDENCE IN PREGNANT, LABORING AND POSTPARTUM WOMEN IN THE REPUBLIC OF DAGESTAN
Authors: GATSAYNIEVA HADIZHAT A. ,   Republican Clinical Hospital No. 2, Makhachkala, KONOVALOV OLEG E. , SHULAEV ALEXEY V. ,   Institute of Medicine, Patrice Lumumba Peoples’ Friendship University of Russia,   Kazan State Medical University
Published: July 2024

Abstract. Introduction. In accordance with the concept of Russia’s demographic policy for the period until 2025, the priorities include reducing the level of reproductive losses, strengthening the reproductive health of the population, and finding reserves to increase birth rates. Aim of the study is to analyze the dynamics and trends in birth, and morbidity rates among pregnant women, women in labor, and postpartum, as well as maternal mortality in the Republic of Dagestan. Materials and Methods. Materials were taken from official statistical reports for the period 2013-2022. The above rates were compared for the Republic of Dagestan, the North Caucasus Federal District, and the Russian Federation as a whole. In analyzing time series, the main trends in rates changing were identified by modeling trends using the approximation method. Results and Discussion. In 2013-2022, the birth rates in the Republic of Dagestan were constantly higher than in the comparison territories. At the same time, among the constituent regions of the North Caucasian Federal District, the Republic of Dagestan ranked 3rd out of 7 in terms of birth rates in 2022. The structure of morbidity among pregnant women in the North Caucasian Federal District, the Russian Federation as a whole, and the Republic of Dagestan is very similar, and the most common are the threat of miscarriage and premature birth. The proportion of normal births in the Republic of Dagestan during the entire observation period was lower than in other territories, but unlike the latter, it had a statistically significant upward trend. At the same time, in the structure of morbidity among women in labor and postpartum, about a half was accounted for by pre-existing hypertension, approximately 1/3 was accounted for by moderate preeclampsia, and 1/10 was accounted for by severe preeclampsia. Maternal mortality in the Republic had significant year-over-year fluctuations and most often exceeded the relevant rates in the territories of comparison. Conclusions. Organizational and managerial decisions aimed at improving the medical and demographic situation in the Republic must be developed and implemented taking into account the current trends in the rates of birth and morbidity among pregnant women, women in labor and postpartum, as well as in the maternal mortality rates.
CARDIOVACULAR COMORBIDITY IN PATIENTS WITH PSORIASIS
Authors: MUTALOVA ELVIRA G. ,   Bashkir State Medical University, ARSLANOVA RENATA M. , KHISMATULLINA ZAREMA R. , NIGMATULLINA ALBINA E. , GALYAUTDINOVA VELENA R. , KAMALTDINOVA GULNARA J. , ASADULLINA GULNARA V. , SAMIGULLINA LIANA I. , RUSTYAMOVA ZULFIYA YA. , SADIKOVA REGINA I. , FRID SVETLANA A. , KAMALTDINOV ELDAR R. , MUSINA FLARISA S. ,   Physician at the Hippocrates MC, Sterlitamak,   Bashkir State Medical University,   Bashkir State Medical University,   Bashkir State Medical University,   Bashkir State Medical University,   Bashkir State Medical University,   Bashkir State Medical University,   Bashkir State Medical University,   Bashkir State Medical University,   Bashkir State Medical University,   Bashkir State Medical University,   Bashkir State Medical University
Published: July 2024

Abstract. Introduction. Psoriatic disease is a genetically determined disease of a multifactorial nature that affects about 2% of the population. According to modern concepts of this pathology, there is a high level of comorbidities, especially those associated with damage to the cardiovascular system. The aim of the study is a comprehensive analysis of the features of epidemiological and clinical data linking psoriasis with cardiovascular risk factors and cardiovascular diseases. Material and Methods. A review and analysis of modern scientific data in the databases, such as eLibrary, PubMed/Medline, Web of Science, Google Scholar, and Cyberleninka for the period from 2000 to the present. Results and Discussion. Up-to-date information has been collected regarding comorbid cardiovascular pathology in psoriasis. We systematized the data related to the analysis of possible pathophysiological mechanisms that justify this relationship and analyzed the methods of cardiovascular risk stratification in patients with psoriasis. Conclusions. Various studies have shown that psoriasis is associated with a higher prevalence of cardiovascular diseases, including hypertension, diabetes mellitus, dyslipidemia, obesity, and metabolic syndrome. The relationship is discussed between psoriasis severity and the risk of developing cardiovascular diseases, as well as prognostic risks with mortality rates. The common pathogenetic mechanisms proposed include genetic factors, inflammatory pathways, adipokine secretion, insulin resistance, lipoprotein composition and function, angiogenesis, oxidative stress, and hypercoagulability.
Kajian Literatur Penggunaan Media Pembelajaran pada Mata Pelajaran Bahasa Indonesia Berbasis PBL
Authors: Eka sari Lilis , Ahmadi Anas
Published: July 2024

This article review aims to collect and review articles that discuss the use of learning media in Problem Based Learning (PBL) based Indonesian language subjects. The research method used is descriptive qualitative with a literature review approach to articles in the last 10 years and obtained 10 articles that meet the requirements. Data collection was done through a literature review of previous articles related to the research. The findings obtained in this study indicate that there are a number of learning media that can be used in Problem Based Learning (PBL) based Indonesian language subjects, namely serialized picture media, wordwall media, animated video media, booklet media, comic media, spinning wheel media, and audio visual media. The conclusion that can be drawn is that these learning media are feasible to use to convey learning materials easily in Problem Based Learning (PBL) based Indonesian language subjects.
Falsafah and Evidentialism. A Review of: Booth, A. Analytic Islamic Philosophy. New York & London: Palgrave Macmillan, 2018, 222 pp.
Authors: Karpov Kirill V. ,   RAS Institute of Philosophy
Published: July 2024

This article discusses Anthony Booth’s book “Analytic Islamic Philosophy”. This book is an introduction to Islamic philosophy, from its origin in the Middle Ages to its contemporary forms. A. Booth uses the language and conceptual apparatus of contemporary analytic philosophy in his exegesis, thereby attempting to bring the legacy of Islamic philosophy into focus. The central theme of the book is an evidentialistic interpretation of the special epistemic status of the prophet. The main figures of Medieval Islamic philosophy — al-Kindī, al-Fārābī, Ibn Sīnā, al-Ġazālī, Ibn Rušd — are presented in chronologically order, together with an introduction to the basic themes of Islamic theology and the Greek philosophical tradition. The book then briefly introduces what the author calls “pre-modern” figures, including al-Suhrawardī, Mullā Ṣadrā and Ibn Taymiyyah, and all these thinkers, along with their medieval predecessors, are presented as forerunners to the more modern incarnation of Islamic philosophy, Political Islam. I question A. Booth’s use of the Cliffordian evidentialism (based on famous Clifford’s Principle) to analysis of the central problem. Firstly, this kind of evidentialism is very outdated and cannot in any way be regarded as a concept of contemporary analytic philosophy. Secondly, it is not immune to the objection from doxastic limits, which Booth does not mention. This objection, however, opens up new possibilities for analysis of the evidentialism and new hermeneutic ways of interpreting concepts of prophetic knowledge in the Islamic philosophical tradition. Thirdly, Booth’s analysis can be much more adequately conducted not by introducing many different kinds of evidentialism, but rather by the concept of doxastic practices. In the conclusion I consider the question in what ways contemporary analytic philosophy can be useful for the history of philosophy.
Depression Among Hiv-positive Individuals Attending the Antiretroviral Treatment Clinics of Wolaita Zone, Southern Ethiopia,2021
Authors: Arba Aseb , Awoke Nefsu , Teshome Mistire , Lolaso Tsegaye , Paulos Kebreab , Samuel Serawit , Desalegn Beimnet , Uka Yohannes Yaya
Published: July 2024

Introduction:
People who are infected with HIV are more likely to develop depression than the general population. It is one of the causes of poor adherence to Anti-retroviral therapy and worsens the patient’s condition and leads to death. Most studies conducted in the area addressed a single setting whereas this study was multi-central. So, it is important to assess the prevalence of depression and its determinants among HIV-positive individuals attending ART clinics of Wolaita Zone.
Objective
This study aimed to assess the prevalence and determinants of depression among HIV-positive individuals attending ART clinics in Wolaita Zone, Ethiopia.
Methods and Materials:
Institution-based cross-sectional study was conducted among HIV-positive individuals attending ART clinics of Wolaita Zone. Data was collected from 596 participants. Health facilities were clustered based on the number of patients attending to ART clinics. Then, facilities were selected randomly from the respective clusters. Data was collected through the face-to-face interview. Epi data for data entry and analyzed using SPSS’s version 20. The presence and strength of association were declared when p-value < 0.05 and using AOR in multivariate analysis respectively.
Result
The prevalence of depression among HIV-positive individuals in the Wolaita Zone is 32.6% at 95% CI [29%, 36%]. Marital status, educational status, living with families, family history of depression, place of medical follow-up, presence of Tuberculosis co-infection, and presence of sleep problems are significantly associated with depression among study participants.
Conclusion and recommendation
: The prevalence of depression among HIV-positive individuals in the Wolaita Zone is high. Being single, living far away from family members, having a family history of depression, the presence of sleep problems and TB co-infection, and making medical follow up at governmental facilities are determined to be factors associated with the occurrence of depression among HIV-positive individuals attending ART clinics of Wolaita Zone. Therefore, psychological support with differential counseling of patients on ART based on their specific needs is essential to minimize the occurrence of depression. In addition, early screening and treatment of TB co-infection, and depression are very important.
The effectiveness of the nurse-manager dualistic intervention program guided by appreciative inquiry on job burnout of nurse (NMDI) : A pilot randomized controlled trial
Authors: Shang Dong-Xu , Wang Li-Na , Shi Li-Min , Li Shu-Ying , Guo Yu-Fang
Published: July 2024

AimThis pilot study aimed to measure the feasibility and acceptability of the nurse-manager dualistic intervention program guided by appreciative inquiry on job burnout of nurse.BackgroundAccording to the Job Demand-Resource model, enhancing personal and work resources can alleviate job burnout. And Appreciative inquiry (AI) was an effective method to increase personal and work resources. Thus, a nurse-manager dualistic intervention program based on AI had been developed.MethodsA pilot randomized controlled trial. The intervention group (n = 23) accepted the nurse-manager dualistic intervention program guided by appreciative inquiry on job burnout of nurse (NMDI) (lasting for 9 weeks), while the control group (n = 24) did not. Outcomes was job burnout, it tested using generalized estimated equation (GEE), to verify effectiveness. Qualitative interviews were conducted to verify feasibility and improve the NMDI program, thematic analysis was used Golaizzi seven step Analysis.ResultsThe intervention group had statistically lower scores for job burnout than the control group, time effects were significant on job burnout (each p < .05). Qualitative research formed two themes, agreed on the feasibility of the NMDI program and further consideration, were identified with four subthemes, confirmed the NMDI program was feasible and effective, and can helped nurse have positive mindset.ConclusionThe NMDI program can reduce job burnout, helped participants establish positive mindset, all participants willing to continue participating in the future.Implications for Nursing Management:The benefits to participating in the NMDI program traversed the individual and organization, nurse managers should support and promote this kind of program and flexible application it in daily nursing management.Trial Registration:This study was approved by the appropriate institutional review board, and Registration No. of Clinical Trial Center: ChiCTR 2100047974, registration date: June 28, 2021. Suggested modifications： 1. Date of registration -Please include the date that your trial was registered in the ‘Trial Registration’ section of the Abstract. 2. Trial registration number -Please include the trial registration number in the ‘Trial Registration’ section of the Abstract.
Microstructures, crystallography and growth patterns of serpulid tubeworms (Class Polychaeta)
Authors: Grenier Christian , Berent Katarzyna , Rodríguez-Navarro Alejandro B. , Vinn Olev , Checa Antonio G
Published: July 2024

Serpulid polychaetes are global marine worms that secrete tubes of calcium carbonate, in which they live. Despite extensive previous research on their microstructures, there are no crystallographic data and their biomineralization process remains unclear. Herein, we review the microstructures of seven different serpulid species and study their chemical composition, mineralogy and crystallography, using X-ray diffraction, Raman and Fourier transform infrared spectroscopy, scanning electron microscopy, energy dispersive X-ray spectroscopy, focused ion beam, electron backscatter diffraction, and thermogravimetric analysis. Generally, serpulid tubes have a high amount of organic matter (~ 7.5 wt. %), consisting of chitin and proteins, and the calcite is always present as medium to high magnesium calcite. We identified three main microstructures: granular-prismatic and lamello-fibrillar calcite, and fibrous aragonite. They all display an axial texture, which is stronger in the lamello-fibrillar calcite, with the c-axis aligned with the elongation axis of the crystals. Our findings demonstrate that only some instances of the granular-prismatic and the lamello-fibrillar calcite are biogenic (primary) microstructures. Conversely, other instances of the granular-prismatic calcite and the fibrous aragonite are a consequence of a recrystallization process (i.e. secondary). Substitution may occur on either primary or secondary calcitic microstructures (replaced by aragonite). Secondary microstructures retain remnants of the previously substituted microstructures, such as vestigial crystals or major growth increments. The high-Mg nature of the calcite favors the recrystallization processes. We hypothesize that the plywood arrangement of the lamello-fibrillar is obtained by the ordering of a chitin fibrillar precursor into a cholesteric liquid crystal phase. Subsequently, calcite would grow by oriented nucleation onto the organic fibrils.
Characterization of the AGR2-NPM3 axis uncovers the AGR2 involvement in PD-L1 regulation in colorectal cancer
Authors: Martisova Andrea , Faktor Jakub , Sosolikova Tereza , Klemesova Iveta , Kolarova Tamara , Holcakova Jitka , Hrstka Roman
Published: July 2024

Despite extensive research, the molecular role of AGR2 in the progression and metastasis of colorectal cancer (CRC) has not been fully characterized. We used quantitative mass spectrometry (SWATH MS) to identify differentially expressed proteins in paired CRC cell models of the SW480 and SW620 cell lines in response to AGR2 protein level manipulation. Relying on the results from SWATH MS and subsequent immunochemical validation, we selected NMP3 as the top candidate protein associated with AGR2 in CRC tumour cells in our screen. RT‒qPCR and immunochemical analysis confirmed the involvement of AGR2-mediated regulation of NPM3 at the transcriptional and posttranscriptional levels. Since PD-L1 is a constituent of the NPM3 regulatory axis, we aimed to correlate the changes in PD-L1 to the differential expression of AGR2 in our cell models. We found that AGR2 positively regulates PD-L1 levels in both SW480 and SW620 cell lines; additionally, several different CRC patient transcriptome cohorts confirmed the association of AGR2 with PD-L1. Our work reveals a new AGR2-NPM3 regulatory axis and the involvement of AGR2 in the regulation of PD-L1, which paves the way for the association of AGR2 with immune evasion in CRC cells.
The impact of Chlamydia infection on semen parameters and male fertility: A systematic review and meta-analysis
Authors: Song Yuanzhi , Yu Chengjun , Weng Wuhong , Liu Maolin , Yan Hao , Sun Miao , Wu Shengde
Published: July 2024

Background and objective:
There has been no consensus regarding whether Chlamydia impacts on males’ reproductive function. This systematic review and meta-analysis compared semen parameters of Chlamydia (+) males with Chlamydia (-) males.
Method
The databases MEDLINE, Embase and PubMed were searched for relevant studies.
Results
Sixteen studies were included with more than 3000 patients. Chlamydia infection negatively impacted on sperm concentration (DM -3.33, 95% CI: -6.54 to -0.12; P = 0.04; I2 = 30%) and progressive motility (DM -1.62, 95% CI: -3.04 to -0.20; P = 0.03; I2 = 14%) in infertile males. Semen volume, sperm normal morphology, sperm vitality and semen pH may not be associated with Chlamydia infection in infertile males. Chlamydia infection may influence semen volume with combining with region factor (DM -0.87, 95% CI: -1.29 to -0.44; P < 0.0001; I2 = 33%).
Discussion and conclusions:
Chlamydia infection deteriorates infertile males’ reproductive function. These finds induce us to consider Chlamydia’s contribution to males’ reproductive dysfunction, and the treatment of Chlamydia whether protect males’ reproductive function should be studied in the future.