bluuebunny/crossref_metadata_2025 huggingface dataset:
CORRUPTION MANIFESTATIONS IN THE SYSTEM OF ECONOMIC SECURITY OF ECONOMIC ENTITIES
Authors:   Lviv State University of Internal Affairs, Zhyvko Zinaida , Hura Vadym ,   KROK University
Published: April 2023

The article establishes the impact of corruption on the economic and national security of the country, what dangers and threats it poses to economic entities. The role of corrupt practices in the economic activity of economic entities was considered. The approaches of scientists to the understanding of the concept of "economic security" were studied and the author's interpretation of it was proposed. Thus, economic security is proposed to understand the state of protection of economic interests of individuals, society and the state from internal and external threats, which contributes to economic development. The most negative consequences of the impact of corruption on the economy, creating a threat to the economic and national security of the country, have been disclosed. These include the expansion of the shadow economy, violation of market competitiveness, inefficient use of budget funds, higher prices for products as a result of "corruption costs", deterioration of the investment climate, increased corruption in non-governmental organizations, the merger of crime and the legal economy, lack of effective private owners, declining confidence in the state, etc. It is also noted that corruption has a positive impact on the economy and political development of the country. The dynamics of the Corruption Perception Index, corruption manifestations are analyzed. The causes of obstacles to foreign investment in the economy of Ukraine, the severity of different types of corruption and the level of corruption in different areas of public activity according to the results of a survey of the population and businessmen, conducted by the National Agency for the Prevention of Corruption in 2021, were studied. It is noted that Ukraine is doing a lot on the way to overcome corruption, but its efforts do not achieve the desired success because of the habituation to corruptive manifestations of the population. The impact of corruption on different spheres of social life and sectors of the economy, enterprises of different types and forms of ownership was characterized. It is noted that the main emphasis in combating corruption should be focused on the ways of determination, and the main determinants of corruption have been identified. The factors forming the demand for corrupt agreements and becoming threats to the economic security of economic entities have also been studied. The directions of prevention of corruption threats to the economic security of the country and entrepreneurship are proposed.
RELATIONSHIP INVOLVED BY VIETNAMESE SMALL BUSINESSES BETWEEN CAPITAL STRUCTURE AND FIRM PERFORMANCE
Authors:   Ho Chi Minh City College of Industry and Trade, Duong Nhan Thi , Nguyen Thanh Cong ,   Ho Chi Minh City College of Industry and Trade
Published: April 2023

From data collected from 126 small and medium enterprises in HCM City, the paper was conducted to examine the connection between capital structure, ownership structure and operational efficiency of Ho Chi Minh City's small and medium businesses. The purpose of the article is to study the interdependence between the capital structure and the results of the small business firm of Vietnam. The author analyzes data based on different methods to contribute additional previous studies follow four dimensions: operational efficiency is measured by DEA model, instead of using the financial ratio in order to verify the theory's predictions agency costs; shows that the operating effectiveness is an important factor in choosing the capital structure for some industries; test whether some hypothesis can dominate each other in various segments of the distribution of leverage or not; and provide fresh empirical data on the connection between capital structure, ownership structure, and operational effectiveness. Future studies can look into the connections between company sizes, market measurements for business financial success, and capital structure. Future research may use the decide methodology with the moderator proxy being company size. The study's findings might be improved even more as a result.
FEATURES OF ACCOUNTING AND WAYS OF ITS IMPROVEMENT AT ENTERPRISES IN THE CONSTRUCTION INDUSTRY
Authors:   Mykhaylo Tugan-Baranovskyi Donetsk National University of Economics and Trade, Shevchenko Lyubov , Kozhukhova Tetyana ,   Mykhaylo Tugan-Baranovskyi Donetsk National University of Economics and Trade
Published: April 2023

This article summarizes the arguments and counterarguments within the scientific discussion on the peculiarities of accounting and ways of its improvement at construction enterprises of Ukraine. The purpose of the article is to determine the features of the accounting of construction enterprises and to develop practical recommendations for its improvement. The research used a complex of general scientific methods: analysis and synthesis, induction and deduction, theoretical generalization, grouping and classification, logical generalization, and comparative comparison. The methods of logical generalization were used in the study of accounting features at construction enterprises. Proposals based on the results of the study of accounting in construction enterprises were developed using the methods of concretization and systematization. According to the results of the study of economic sources of information, an analysis of the construction industry was carried out in order to determine the peculiarities of the accounting of construction enterprises. In order to increase control over the formation of the cost of construction works, additional sub-accounts to account 23 "Main production" have been proposed to analytically form costs in construction. It is proposed to introduce into the standard Plan of accounting accounts, accounts 238 "Unfinished construction contracts", 239 "Interim accounts", which will ensure uniform requirements for accounting in construction and a reliable reflection of the technology of the construction process in accounting and financial reporting. The practical use of the results of the conducted research will allow to increase the efficiency of accounting of construction enterprises, its efficiency, analytical, mobility, will strengthen both control and management functions of accounting and management accounting.
ANALYSIS OF MECHANISMS OF INTERACTION BETWEEN PUBLIC AUTHORITIES AND PUBLIC ORGANIZATIONS AT THE LOCAL LEVEL
Authors:   Simon Kuznets Kharkiv National University of Economics, Gavkalova Natallia , Yeromka Danylo ,   Simon Kuznets Kharkiv National University of Economics, Tabatskyi Maksym ,   Simon Kuznets Kharkiv National University of Economics
Published: April 2023

The article analyzes the problem of ensuring the effectiveness of the interaction of public authorities with the public, the existing mechanisms of interaction, their characteristics and features of application. Attention is devoted to the regulatory and legal basis of the forms of participation of civil society institutions in the management of state affairs. The values and principles of interaction between the government and the public and the principles of public organization in the formation and implementation of state policy are defined. Various approaches of scientists to the definition of problems of effective cooperation between state authorities and civil society organizations are considered. Modern scientific developments in the interaction of civil society institutions with the state authorities of Ukraine have been revealed. The legal forms of interaction between civil society institutions and the state authorities in Ukraine are defined and disclosed. It is emphasized that public organizations during interaction with state and self-government bodies influence their legitimacy. It is noted that public organizations exercise direct control over the conduct of national and local elections. The relationship between state authorities and the public in the context of crisis phenomena, organizational mechanisms for studying public opinion in order to obtain objective and reliable information is considered. Within the framework of the work, it was noted that today in the implementation of state policy, the objective is the tendency towards the increasing involvement of civil society organizations in the performance of its tasks. In this regard, it was stated that there is a growing need for accessibility, accountability and responsibility of authorities, strengthening of control mechanisms in anti-corruption and other issues sensitive to public opinion. This article draws attention to such threats that may arise in the process of interaction of the above-mentioned subjects as attempts to use public organizations and their potential in political struggle, as well as insufficient financial base, lack of human capital in non-governmental organizations. Important mechanisms of interaction between state authorities and non-governmental organizations are assessed.
STATE POLICY AND ADMINISTRATION CHALLENGES IN THE GENERAL EDUCATION SYSTEM OF GEORGIA
Authors:   University of Wroclaw, Khuroshvili Bacho
Published: April 2023

Issues of state policy and administration of general education nowadays are becoming quite relevant, both for political-administrative science and political agenda. Academic rhetoric and existing research provide important messages that prevent the seemingly "liberal-democratic" Georgian educational system from functioning effectively and efficiently. The purpose of the research is to study, identify and analyze the problems and challenges related to the education policy and administration in the general education system of Georgia. The objectives of the research are the study of the design of the state policy of general education of Georgia, and the analysis and evaluation of the policy of administration and implementation. Qualitative and quantitative methods of social science research are used in the research. The analysis of documents and the interpretation of quantitative data made the reality of the Georgian general education system more visible, and the expert interviews showed us additional problems that could not be obtained as quantitative data. The research reveals that the institutional design of the general education system of Georgia is full of ambitious values and goals, the implementation and administration process of which is actually unattainable, which causes its facade. The results of the study indicate that the legal and unequal status of students, problems related to minorities, religion, and discrimination, challenges linked to the safety of students and their bio-psycho-social development, low learning results, the outflow of students from the general education system, teachers' competencies and professional Ethical issues whose review, evaluation, analysis, and data interpretation are the main findings of this article.
HUMAN CAPITAL AS OBJECT OF SOCIAL RESPONSIBILITY OF BUSINESS AND GOVERNMENT IN THE FORMATION OF PUBLIC POLICY
Authors:   Krivyі Rіh National University, Turylo Anatolii , Arkhypenko Svitlana ,   Krivyі Rіh National University, Adamovska Viktoriia ,   Krivyі Rіh National University
Published: April 2023

Social responsibility represents such a system of relations in the "state - society - business" system, which involves the search and use of a system of motives and incentives for the private sector (business) to take into account the interests of society in its activities, ensuring compliance with social standards in work with personnel. Functioning in conditions of limited resources, both the state and the corporate sector are forced to use available resources more rationally, in particular, human capital, the level of return of which is currently defined as extremely low in Ukraine. That is why the category of human capital needs additional study. The purpose of the article is to identify the features of human capital as an object of social responsibility of business and government in the context of its influence on the quality of the enterprise, its competitiveness. At the same time, such general research methods as analysis and synthesis were used. In the course of the study, the subjects of public policy were identified, one of which is the corporate sector, which through market mechanisms forms the economy of the state, determines its resource capabilities for carrying out this or that policy. This forces us to combine the efforts of the state and business in order to make more effective management decisions. Such socially responsible behavior encourages rational use of resources, one of which is human capital. The article defines the role of human capital; ratio of human capital categories of the enterprise and individual employees; the quality of human capital, manifested in the ability to innovate, and its impact on the innovativeness of the enterprise; issues of personnel development.
Dampak Kepemimpinan Wu Zetian Pada Masyarakat Tiongkok Tradisional Dalam Novel The True Story Of China’s Cleopatra Karangan Jonathan Clements
Authors: Abdullah Artika Gunawan , Budianingsih Tri , Hartati Sri
Published: April 2023

The Tang Dynasty is one of the most famous dynasties in China. In addition to the discovery of many discoveries, this dynasty also has many interesting stories. One of them is the story of Empress Wu Zetian (武则天Wǔzétiān). who is the only female emperor in China. The story of Empress Wu Zetian, the female emperor, has attracted a lot of interest from the public and even novelists. This study reviews the impact of Empress Wu Zetian's leadership on traditional Chinese society in the novel The True Story of China's Cleopatra. The author uses a qualitative descriptive approach, a research approach by examining qualitative sources to examine the impact of Empress Wu Zetian's leadership on traditional Chinese society in the novel The True Story of China's Cleopatra. From the research that has been done, it is known that during her reign, Empress Wu Zetian has made many positive impacts on current traditional Chinese society. Examples such as the existence of a state examination system that can be followed by all circles of society, the abolition of taxes to workers and farmers, the development of Buddhism and also equal rights for women in its time.

Keywords - The True Story of China’s Cleopatra, Empress Wu Zetian, Tang Dynasty, The Impact of her rule
Динамічна інформаційна мережа із вбудованим штучним інтелектом
Authors: Vasylkivskyi M.V. , Boldyreva O.S. , Onyshchuk D.O. , Hnatenko Yu.Yu.
Published: April 2023

Досліджено архітектуру орієнтованої мережі на користувача, яка передбачає використання виділеної абонентської мережі, яка об'єднує всі необхідні функції для надання інформаційних послуг. Враховуючи переваги технології UCN визначено, що орієнтована на користувача архітектура радіомережі природно та ідеально поєднується з децентралізованою технологією, яка є невразливою для DDoS-атак та єдиних точок відмови (SPOF). Розглянуто особливості планування роботи великих мережевих систем за умови гарантованого надання інформаційної послуги із використанням існуючих рішень, що отримані в результаті дослідження роботи центрів обробки даних та застосовуванні їх у масштабі мережі з підтримкою кількох орендарів та паралелізму. Отримані результати дослідження розподілених систем вказують, що головною метою має бути підвищення ефективності, а не оптимальності. Досліджено особливості надання кожному клієнтському пристрою власного «приватного» віртуального екземпляру базової мережі через децентралізовану структуру віртуальних машин чи контейнерів із використанням гнучких програмно-конфігурованих мереж (SDN) та віртуалізованих мережевих функцій (NFV). Розглянуто ідеологію архітектури UCN, яка полягає у формуванні фундаментальної, гнучкої, безпечної та надійною мережевої архітектури із простою структурою та повним набором функцій. Вказані функціональні характеристики підвищують довіру мережі 6G. Досліджено особливості формування цифрового домену користувача спираючись на підхід UCN з чітко вираженою границею, що містить ресурси даних, такі як профіль користувача, профіль служби та профіль ресурсів (включаючи мережні ресурси, так і ресурси кінцевого обладнання). В результаті, визначено правила керування цінними цифровими активами, що належать користувачеві у повній відповідності з нормативними вимогами до безпеки та конфіденційності.
Формалізація технологічного процесу діагностики програмного забезпечення після впливу кібератак
Authors: Dobryshyn Yu.Ye. , Bondarenko I.D. , Sydorenko S.M.
Published: April 2023

В роботі розглядаються питання застосування логіко-математичного апарату при формалізації процесів діагностування програмного забезпечення після його пошкодження (внаслідок впливу кібератак), під час експлуатації автоматизованих інформаційно-телекомунікаційних систем та комплексів. Запропоновано математичний апарат автоматизації процесу діагностування програмного забезпечення, який використовує логіку предикатів та дозволяє застосовувати математичні вирази, що описують властивості дефектів програмного забезпечення, правила їх виводу, відповідно до положень, прийнятих в математичній логіці. Приклади описів проектних рішень дозволяють автоматизувати проектування технологічних операцій діагностування пошкодженого програмного забезпечення після впливу кібератак, а також, забезпечують створення логічних проектних процедур щодо операцій відновлення пошкодженого програмного забезпечення.
APPLICATION OF BLOCKCHAIN AND ARTIFICIAL INTELLIGENCE IN BANK RISK MANAGEMENT
Authors: Dzhaparov Plamen
Published: April 2023

The transformation from analogue to digital risk management is becoming a prerequisite in the implementation of the incresingly digital bank institutions’ strategies. Among the key steps in this direction is the optimal use of blockchain technology’s potential and artificial intelligence. Huge hopes are set on blockchain in view of two key risks facing today’s banks: the danger of using the bank system for money laundering and financing terrorism, and cyberattack threat. Artificial intelligence, in turn, creates conditions for processing large arrays of unstructured data risk, more precise identification of potential problems in the future, full automation of manual processes in risk function, credit scoring automation, developing adequate market risk assessment models, etc.
DECISIONS AND SKILLS OF THE STRATEGIC LEADERS
Authors: Stamevska Elizabeta , Stamevski Vasko
Published: April 2023

Strategic leaders are known for thinking ahead, preparing for succession, and implementing a strategy. If companies are struggling in these areas, then it would make sense to take a look at bringing in a strategic leader.
Strategic leaders do not make decisions or move forward without running decisions through a strategic lens. They are disciplined in always keeping the objective first. They will not make a quick decision, but they will decide if it fits with the short and long-term goals of the company.
Strategic leadership links the personal attributes of the leader with their professional knowledge and experience. Because strategy is no longer a top-down activity but is the responsibility of many people within an organization, demanding a culture of strategic innovation and openness, leaders must be able to connect their leadership imperative with the culture and practice of the wider organization, thereby delivering sustained impact and influence through individuals, teams and business units.
Recent Advances in Rapid Diagnosis and Analysis of Infectious Agents in Human Blood Stream
Authors:   Department of Microbiology, S.M.M.H. Medical College, Saharanpur, UP, India, Singh Pradeep Kumar , Singh Shweta Kusmakar ,   Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India
Published: April 2023

The ability to rapidly diagnose and analyze infectious agents such as pathogens in human blood stream is considered pivotal and an important step for patient treatment and effective monitoring. This is also essential to ensure the safety of the donor blood supply. This has driven research in medical biotechnology and the focus has been on developing rapid diagnostic ability that enables detect and identify pathogens in blood borne infections. This research seeks to mitigate the challenges involving infections such as pathogens induced sepsis. These infections are believed to be a major cause of mortality in hospitalized patients worldwide. It is of general consensus that establishing a rapid diagnosis would not only enable an early and adequate antimicrobial therapy but it would also result in positive clinical outcomes for patients. In this perspective, we have presented a brief overview of some of the notable recent advances in diagnostics to detect infectious agents in human blood.
ECTI Transactions Manuscript Format (Word template)
Authors: CIT ECTI
Published: April 2023

ECTI-CIT
قراءة في عملية الدفع الالكتروني للضريبة
Authors: الحرازي محمد
Published: April 2023

لتطور سنة الحياة وقد قيل في عبارة مشهورة: "من لا يتطور يتدهور، ومن لا يتجدد يتبدد، ومن لا يتقدم يتقادم"، تنطبق هذه المقولة على الأفراد والمنظمات وحتى الدول على السواء، ذلك أن التغيرات في مجريات الحياة مضطردة، ومتوالية، ومتطلبات مواكبتها مُجهدة ومكلفة.

في هذه الجانب لا شك أن حكومة أي دولة في سبيل الارتقاء بخدماتها العامة تسعى لمراعاة تلك الأمور، والأخذ بأحدث الوسائل التي تضمن جودة خدماتها وضمان حوكمتها؛ من ضمن ذلك ما يتعلق بآليات ووسائل تحصيل الإيرادات العامة التي من أهمها الإيرادات الضريبية، للتسهيل على المكلفين دفعها إلى الخزينة العامة بأيسر الطرق وأضمنها.

ولذلك فإن أهمية هذا البحث المتعلق بالدفع الالكتروني للضريبة في هذه المرحلة المهمة التي تضرب فيه جائحة كورونا العالم، وتلقي بظلالها على شتى مناحي الحياة السياسية والاجتماعية والإدارية والاقتصادية وغيرها، تأتي في محاولة لاستجلاء بعض جوانب العناصر المتعلقة بعملية الدفع الالكتروني للضريبة في بعض الدول.

الكلمات المفتاحية: رقمنة الضرائب، الدفع الالكتروني للضرائب، التحصيل الالكتروني، واقع التحصيل الالكتروني
تعدد الزوجات في القانون الدولي الخاص: صراع ثقافي وتنازع في القوانين
Authors: سلطان نافع
Published: April 2023

إن ظهور النزاعات الخاصة بتعدد الزوجات عبر الحدود يثير إشكاليات عدة في ميدان القانون الدولي الخاص؛ فالعلاقات الزوجية التعددية ذات الصفة الدولية تترك أثراً واضحاً في فلسفة القانون الدولي الخاص ومناهجه، وتضع تحديات مختلفة أمام تطبيق قواعد تنازع القوانين، سواء في مرحلة التكييف، أو عند تحديد القانون الواجب التطبيق، أو حتى عند استخدام منهج الاعتراف. كما أنه لم يكن من اليسير دائماً تطبيق القانون الأجنبي بسبب تباين التطبيقات القضائية عند الاحتجاج بالنظام العام الدولي. فالهدف من البحث هو تحديد إمكانية المحاكم العربية والغربية في مراعاة ثقافة تعدد الزوجات، عند تطبيقهم لقواعد القانون الدولي الخاص، وقدرتها على تذويب الصراع الثقافي بوسيلة حلول تنازع القوانين.

الكلمات المفتاحية: تعدد الزوجات، الصراع الثقافي، تنازع القوانين، قانون الزوجين، الدين، النظام العام الدولي، قانون القاضي، الاعتراف بالزواج الثاني.
JUVENILE DELINQUENCY: FEATURES, CAUSAL COMPLEX
Authors: Демидова-Петрова Е. В.
Published: April 2023

Введение: в статье освещается комплекс основных причин преступности несовершеннолетних. Особое внимание уделяется семье как институту социализации личности. Также рассматривается глобальный информационный фактор, или онлайн-фактор, как один из современных факторов, оказывающих значительное влияние на преступность несовершеннолетних. Материалы и методы: всеобщий диалектический метод познания явился методологической основой статьи. Также автором применены общенаучные и частнонаучные методы познания: историко-правовой метод, системно-структурный анализ, аналогия, обобщение, сравнение, дифференциация, моделирование, наблюдение, аналитическое обследование. Результаты исследования: рассмотрена семья как один из основных этапов социализации несовершеннолетнего, а также проанализировано семейное неблагополучие, которое является одним из основных факторов, лежащих в основе исследуемого вида преступности. Предложены результаты авторского исследования, направленного на установление особенностей формирования личности современного несовершеннолетнего преступника, а также выявление основных причин преступности несовершеннолетних. Обсуждение и заключение: автор указывает на взаимосвязь семейного неблагополучия и значительного времяпрепровождения несовершеннолетних в интернет-пространстве, онлайн социальных сетях, что является одним из детерминирующих факторов преступности несовершеннолетних.

Introduction: the article highlights the complex of the main causes underlying juvenile delinquency. The author pays special attention to family as the institution of personal socialization. The global information factor, or online factor, is also considered as one of the modern factors that have a significant impact on juvenile delinquency. Materials and Methods: the universal dialectical method of cognition was the methodological basis for the article. The author also applied general scientific and specific scientific methods of cognition: historical and legal method, system-structural analysis, analogy, generalization, comparison, differentiation, modeling, observation, analytical examination. Results: the family is considered as one of the main stages of socialization of a person of juvenile age, as well as family problems are analyzed, which is one of the main factors underlying the type of crime under study. The results of the author's research are proposed, which is aimed at establishing the features of the formation of the personality of a modern juvenile delinquent, as well as identifying the main causes of juvenile delinquency. Discussion and Conclusions: the author points out the relationship between family problems and significant pastime of juveniles in the Internet space, social networks, which begins to form one of the factors of juvenile delinquency.
Urban Regeneration and Sustainable Building Transformation: Wood As a Building Material
Authors: CERVESATO Alberto
Published: April 2023

The current cultural debate in urban and architectural fields - but not only - sees the emergence of increasing attention to environmental sustainability and related issues, which inevitably condition all the different phases of the project. Reducing land consumption, coping with climate change, improving the energy efficiency of buildings, as well as increasing their level of living comfort, are just some of the goals to be pursued to achieve a generalized improvement of the built environment through application of the typical principles of the so-called urban regeneration. Looking at the internal areas of the Italian territory, concepts are evoked such as the reuse of materials, the reconversion of buildings and sometimes the renaturalization, which is a less usual choice for a highly man-made territory like the Italian one. In this case, therefore, the use of wood as a preferential material for the aforementioned operations, a material which, over the last few decades, has greatly improved from a structural and performance point of view. Finally, a proposal will be made, carried out with the Municipality of Resia, moved precisely by these principles and aimed at being a sort of “model” - and also a stimulus - for the future of planning in these areas.
Renal Histopathology Associated With Kidney Failure and Mortality in Patients With Lupus Nephritis: A Long-Term Real-World Data Study
Authors: Liao Yu-Wan , Chen Yi-Ming , Hsieh Tsu-Yi , Hung Wei-Ting , Hsu Chiann-Yi , Wen Mei-Chin , Chen Yi-Hsing , Huang Wen-Nan
Published: April 2023

Objective

Lupus nephritis (LN), a common manifestation of systemic lupus erythematosus, is associated with a higher risk of kidney failure and death. The renal pathology of LN helps elucidate the severity of inflammation and the extent of irreversible damage. We aimed to identify histologic variables that correlate with risks of kidney failure and mortality.

Methods

Between 2006 and 2019, a total of 526 patients with LN were enrolled. Renal pathology was classified according to the International Society of Nephrology/Renal Pathology Society classification. Components of activity and chronicity indices were analyzed to determine which variables correlated with an increased risk of kidney failure and death, with the adjustment of potential confounders.

Results

During the follow-up period (median 7.5, IQR 3.5-10.7 years), 58 patients progressed to kidney failure and 64 died. In the multivariate Cox regression analysis, tubular atrophy (hazard ratio [HR] 2.28, 95% CI 1.66-3.14) and tubulointerstitial inflammation (HR 3.13, 95% CI 1.34-7.33) predicted kidney failure. The renal outcome was even worse if tubular atrophy and tubulointerstitial inflammation coexisted (10-year kidney survival rate: 63.22%). The presence of cellular crescents was associated with an increased risk of death in male patients with LN (HR 1.91, 95% CI 1.02-3.57), whereas the presence of fibrous crescents predicted death in female patients with LN (HR 5.70, 95% CI 1.61-20.25).

Conclusion

Histologic variables of renal biopsy in LN could be regarded as prognostic indicators for kidney failure and mortality.
Preliminary Clinical and Laser Speckle Contrast Analysis Data on Selexipag Efficacy for the Treatment of Digital Vasculopathy in Systemic Sclerosis
Authors: Di Battista Marco , Della Rossa Alessandra , Da Rio Mattia , De Mattia Giammarco , Morganti Riccardo , Mosca Marta
Published: April 2023

Objective

Systemic sclerosis (SSc) is burdened by Raynaud phenomenon (RP) and digital ulcers (DUs), and sometimes standard vasoactive therapies are ineffective or contraindicated. Selexipag is an oral selective IP prostacyclin receptor agonist approved for the treatment of SSc-related pulmonary arterial hypertension. We aimed to evaluate the clinical and instrumental efficacy of selexipag in SSc digital vasculopathy.

Methods

Patients with SSc with severe digital vasculopathy refractory or with contraindication to all other vasoactive therapies were administered selexipag. RP- and DU-related clinical outcomes were evaluated, and digital perfusion was assessed by laser speckle contrast analysis (LASCA), all at baseline and after 3 months.

Results

Selexipag was administered to 9 patients with SSc (66.6% female, mean age 52.3 [SD 16.6] yrs). One patient had to stop the drug because of adverse effects. After 3 months of selexipag administration, there was a significant reduction in RP daily episodes (P= 0.01) and RP mean duration (P= 0.04). The number of DUs decreased from 10 to 4 without reaching statistical significance. A significant improvement in mean perfusion of the fingers (P= 0.02) was observed with LASCA.

Conclusion

Selexipag showed good potential for the treatment of SSc digital vasculopathy. Our results are certainly preliminary, yet quite encouraging. New trials for the evaluation of selexipag efficacy in SSc digital vasculopathy are needed.
Évaluer la qualité des relations éducatives pour favoriser le bien-être : une utilisation possible du Classroom Assessment Scoring System (CLASS) ?
Authors: Martin Marlène , Haag Pascale
Published: April 2023

La qualité des relations est reconnue comme un déterminant essentiel du bien-être des élèves à l’école. Pour tenter de l’appréhender, différentes méthodes ont été proposées, dont le Classroom Assessment Scoring System (CLASS), outil d’observation et d’évaluation de la qualité des interactions en contexte éducatif. Élaboré par l’équipe de Pianta, La Paro et Hamre et aux États-Unis depuis 2008 et largement utilisé dans le monde, il est encore peu connu en France. Le présent article décrit cet outil en se centrant sur les dimensions concernant la qualité des relations entre élèves et enseignant-e-s. Il présente ensuite une revue de la littérature internationale explorant son usage pour évaluer les relations et à des fins de formation. En tenant compte des critiques dont il fait l’objet, sont finalement discutées la pertinence et la possibilité de son utilisation pour évaluer et former à la qualité de la relation éducative, dans le contexte français.
Ensemble, on va plus loin ? Différences d’appréciation du travail à plusieurs chez des élèves de primaire
Authors: Legavre Amélia
Published: April 2023

L’article s’intéresse à l’appréciation des modalités de travail à plusieurs par des élèves de trois classes de cycle 3, sur la base d’observations dans ces classes et d’entretiens avec leurs 67 élèves. Il s’interroge sur le rôle de ces interactions dans l’expérience des élèves, de leur propre point de vue : les élèves apprécient-ils le travail à plusieurs et si oui, l’apprécient-ils pour les mêmes raisons ? Les résultats montrent que les interactions entre élèves en classe sont dans l’ensemble appréciées, mais que certains élèves de niveau scolaire élevé valorisent plusieurs modalités de travail à plusieurs, là où les élèves de niveau scolaire plus faible valorisent surtout ce qui s’oppose aux activités les plus formelles de la classe. Une seconde partie s’intéresse à l’expérience des élèves peu sûrs d’eux, qui trouvent dans le travail à plusieurs une source de réconfort qui les protège de situations déplaisantes, pour faire face à leurs difficultés académiques ou relationnelles. Enfin, les élèves niveau élevé et plutôt sûrs de leur statut au sein de la classe défendent l’intérêt des interactions sur le plan intellectuel. Ainsi, il est possible de conclure que les interactions entre élèves en classe améliorent leur expérience, mais pour des raisons différentes en fonction de leurs profils.
Effectiveness of Vacuotherapy and Dry Needling as Adjunct Treatment for Musculoskeletal Cases: A Cohort in a PT Clinic
Authors: Balisi Adnan , Lobaton Vince Paul , Jegira Jhonas Santi A. , Debulgado Dane Marie O. , Tumonong Mae Adrinne , Brillas Christian James , Gelito Ritchie Belle S. , Marasigan Mychelle Rae R.
Published: April 2023

Introduction: Usage of vacuum therapy and dry needling in physical therapy management of musculoskeletal cases have gained increasing usage but there is a limited number of literatures regarding its effect. This study determines the effect size of the interventions, which are vacuotherapy and dry needling as adjunct treatment to exercises, performed in a local PT clinic to musculoskeletal cases in three different treatment sessions with a week gap in between. Methods: The study is a retrospective-cohort where sampling was purposive in gathering historical patient charts. The numerical pain rating scales and relevant range of motion in the musculoskeletal cases were collected for analysis. Results: Results showed large significant reduction in pain scale between sessions but no significant changes in all ranges of motion across different anatomically categorized musculoskeletal cases. Discussions: The results of this study imply that using vacuum therapy and dry needling as adjunct to therapeutic exercises can reduce pain intensities significantly but not ROM. Further research is recommended regarding effects of these tools for ROM and their retention of effects.
ANALYSIS OF THE RELIABILITY OF AUTOMATED ELECTRIC MOTOR DRIVES OF CABLE CARS AT SKI FIELDS
Authors:   Academy of Applied Studies, Kosovo and Metohija, Zvečan, Serbia, Bogićević Zorica , Petković Martina ,   Academy of Applied Studies, Kosovo and Metohija, Zvečan, Serbia, Kojić Dejan ,   University of Business Engineering and Management, Technical Faculty, Banja Luka, Bosnia and Herzegovina
Published: April 2023

The basic questions that arise when maintaining an automated electric drive relate to the safety and reliability of the elements in operation. The maintenance strategy of these elements is planned to start from the basic facts related to the plant’s importance, type and purpose. The main purpose of maintenance is the timely detection of a fault and its elimination, i.e. ensuring continuous operation of the plant. In this work, the operation of the cable car was analyzed by monitoring the reliability of the electric drive. An analysis of the significance of reliability coefficients is a potentially new method for maintenance planning. The aim of the research was to define a new strategy for the maintenance of the facility and ensure the maximum safety of skiers through the analysis of previous events. Research is based on coefficients that indicate the reliability, frequency of failures, availability and unavailability of the elements that make up a drive. The essence of the conducted research is based on a new strategy for planning and maintaining such a facility, aiming to ensure skiers’ safety and protection.
MODEL FOR EVALUATING THE PLASMA COATING METHOD
Authors:   Institute of Mechanical Engineering of the Russian Academy of Sciences named after A.A. Blagonravov (IMASH RAS), Moscow, Russia, Kravchenko Igor ,   Russian State Agrarian University – MTAA named after K.A. Timiryazev, Moscow, Russia, Kuznetsov Yury ,   Orel State Agrarian University named after N.V. Parakhin, Orel, Russia, Yarina Svetlana ,   Russian State Agrarian University – MTAA named after K.A. Timiryazev, Moscow, Russia, Dobychin Aleksey ,   Orel State Agrarian University named after N.V. Parakhin, Orel, Russia, Spasić Dejan ,   University “UNION-Nikola Tesla” Belgrade, Faculty of Applied Sciences, Niš, Serbia, Kalashnikova Larisa ,   Orel State University named after I.S. Turgenev, Orel, Russia
Published: April 2023

The article considers the main prospects for the use of the method of coating plasma spraying. The essence of plasma spraying is disclosed, and the main advantages and disadvantages of this coating formation method are indicated. The method is characterized by high productivity and the possibility of forming high-quality coatings on machine parts for various functional purposes. It was found that the low stability of the spraying process, the structural complexity of the plasmatron and the need for mathematical modeling are constraining factors in designing new technological processes of plasma spraying. The possibility of further increasing the efficiency of plasma spraying by developing methods and means of automation and computerization of the spraying process is substantiated. Obtaining the required physical and mechanical properties of coatings applied to worn working surfaces of machine parts by plasma spraying is achieved by using modern electronic computing machines in the development of technological application processes. Based on the research a mathematical model for evaluating the method of plasma coating deposition was obtained. It allows the choice of applied materials and technological processes, as well as modeling options of design and technology solutions that meet the optimization condition. The data obtained from the results of studies allow evaluation of the impact of technological modes of coating formation on the optimization parameter.
Three-dimensional modelling of tensile behaviour for standard aluminium specimens
Authors:   Institute of Space Technology, Islamabad, Pakistan, Toor Zaigham Saeed
Published: April 2023

The effect of specimen width and incorporation of a circular hole on the tensile behaviour of commercially available aluminium alloy AA 1100 was studied using finite element analysis (FEA) for convergence with the already published experimental work of other researchers. Static structural analysis was conducted to simulate tensile loading of Japanese industrial standard (JIS) specimen JIS Z 2201 No. 13B and No. 5 until the point of the ultimate tensile strength (UTS) was reached. A strain rate of 0.25 mm/s was used for both the neat specimen and the one bearing a circular hole of 8 mm in diameter at the centre of the specimen. The numerical results exhibited a good agreement with the experimental work by comparison of the percentage elongation for numerical and experimental data. The normal stresses calculated using analytical and numerical approaches also reflected a good convergence. For neat specimens of JIS Z 2201 No. 13B and No. 5, a 100 % increase in specimen width enhanced the load required to reach UTS by 100 %, while elongation was increased by 30 %. On the other hand, for specimens of JIS Z 2201 No. 13B and No. 5, bearing an 8 mm circular hole reduced the load required to reach UTS by 300 %, while elongation was only increased by 25 %. The 200 % decrease in load required to reach UTS and 57 % reduction in elongation was observed by incorporating an 8 mm circular hole in the neat specimens.
Effect of Cocos nucifera L. Water on Scopolamine-Induced Memory Impairment in the Wistar Rat
Authors:   Department of Physiology, Lead City University, Ibadan, Nigeria, Oladun Busayo ,   Department of Physiology, University of Ibadan, Ibadan, Nigeria, Oyerinde Abiodun ,   Department of Physiology, Lead City University, Ibadan, Nigeria,   Department of Physiology, University of Ibadan, Ibadan, Nigeria, Oyadeyi Ayodele ,   Department of Physiology, Lead City University, Ibadan, Nigeria,   Department of Physiology , Ladoke Akintola University, Ogbomoso, Nigeria, Ayinde Badmus ,   Department of Crop Protection and Environmental Biology, University of Ibadan, Ibadan, Nigeria, Onasanwo Adetunji ,   Department of Physiology, Lead City University, Ibadan, Nigeria
Published: April 2023

Memory loss is an important Alzheimer's disease indicator (AD) linked with hippocampal damage. Scopolamine (SCO) antagonizes muscarinic acetylcholine receptor (mAChR) whose effect is similar to AD symptoms. Cocos nucifera L. (coconut) water is a crucial biological fluid containing nutritional components, and consumed for its health benefits. This study investigated the effect of C. nucifera water on memory impairment caused by SCO in rats. Thirty-two male Wistar rats were divided into four groups (n=8): control (normal saline); SCO (1 mg/kg/i.p.), C. nucifera water (0.4 mL/20 g) + SCO (1 mg/kg/i.p.), and donepezil (5 mg/kg/i.p.)+ SCO (1 mg/kg/i.p.). The levels of acetylcholinesterase (AChE), brain-derived neurotrophic factor (BDNF), interleukin-6 (IL-6), tumour necrosis factor (TNF-α), and cyclo-oxygenase-2 (Cox-2) were measured. Hippocampal histology was done. Utilizing GraphPad Prism for statistical analy-sis, pre-treatment with C. nucifera water and donepezil displayed higher (p<0.01) spontaneous alternation in the Y-maze, and decreased escape latency, increased entries and time spent in the target quadrant (p<0.01) of the Morris water maze compared to the SCO group. These pre-treatment also inhibited AChE activity (p<0.001), and reduced expressions of IL-6, TNF-α and Cox-2 (p<0.001). However, there were no marked differences (p>0.05) in BDNF across the groups. Histology of SCO-only group revealed degenerated neurons, whereas the pre-treated groups showed regenerated neurons with less necrotic cells. The administration of SCO to the rats resulted in some form of memory impairment, and C. nucifera water showed promise for reversing this deficits
Research Culture of Faculty in Higher Education Institution
Authors:   Isabela State University, M. Nerona Maria Cristina Lalaine , Quijano Michelle G. ,   Isabela State University
Published: April 2023

The purpose of this study was to determine the research culture among faculty members of Isabela State University which was also the population of this research. Total Enumeration sampling was used to determine the respondents among the different programs. A five-point Likert Scale was used and the instruments was validated by experienced professors in the field. As to the profile, majority of the respondents are from the college of education with the age bracket of 26 to 30, female, permanent faculty and has been in the service for 5 years and below. Accordingly, most of them are instructor with master’s degree and doctoral units, and equivalent teaching units of above 24. The study also shows that 61.31% of the respondents presented their paper for the last five years in the international, national and local conferences and categorize as technical, technological, social and educational. Faculty rarely involve in research work and activities. The perceived level of competence in research writing for faculty is good based on the overall mean. The level of involvement of faculty researchers and its profile particularly in educational status and highest educational attainment has significant relationship using Chi Square as the statistical tool. As to the significant relationship of faculty involvement in research and extent of Organization Support to faculty researchers shows significant relationship this means that the Administration should fully support any research activities of faculty members.
Periprosthetic Femur Fracture on Alkaptonuric Patient: A Rare Case Report in Indonesia
Authors:   Resident Medical Officer, Siloam Hospital Denpasar, Bali, Indonesia., Ustriyana Nyoman Gede Grenata Nanda , Darmada Putu Dewinta ,   Resident Medical Officer, Siloam Hospital Denpasar, Bali, Indonesia., Munaf Hasnania Rilanty ,   Global Health/Health Leadership and Management, University of New South Wales, Sydney, Australia., Saspraditya Erwin ,   Department of Orthopaedic and Traumatology Surgery, Siloam Hospital Denpasar, Bali, Indonesia., Sucitra Putu Budi ,   Department of Orthopaedic and Traumatology Surgery, Siloam Hospital Denpasar, Bali, Indonesia.
Published: April 2023

A 74-year-old male with alkaptonuria (AKU) was admitted to the emergency department with left distal femur pain and Rorabeck type 2 periprosthetic femur fracture following total knee arthroplasty (TKA). AKU is an autosomal recessive disorder characterized by homogentisic acid buildup in connective tissues and joints, leading to ochronosis and arthritis. Multiple joint replacements are common in AKU patients, and periprosthetic fractures may occur due to osteopenia. Rorabeck type 2 fracture is treated with intramedullary nailing or locked plating. The patient underwent internal fixation with locking plate and bone grafts using minimally invasive plate osteosynthesis (MIPO) procedure, resulting in good fracture healing. The case highlights the importance of considering AKU as a differential diagnosis in arthritis patients and managing periprosthetic fractures with care in AKU patients.
2019 Türkçe Dersi Öğretim Programı Ortaokul Kazanımlarının Anahtar Yetkinlikler Açısından İncelenmesi
Authors: AYKAÇ Bektaş
Published: April 2023

Bu çalışmada 2019 Türkçe Dersi Öğretim Programı ortaokul kazanımlarının Türkiye Yeterlilikler Çerçevesi’nde yer alan anahtar yetkinlikler açısından incelenmesi amaçlanmıştır. İnceleme sürecinde yabancı dillerde iletişim anahtar yetkinliğinin sahip olduğu özellikler dikkate alınarak Türkiye Yeterlilikler Çerçevesi’nde yer alan sekiz anahtar yetkinlikten “yabancı dillerde iletişim” anahtar yetkinliğine yer verilmemiştir. Çalışmadaki veriler nitel araştırma yöntemlerinden doküman incelemesiyle toplanmış elde edilen veriler betimsel analiz yöntemi ile analiz edilmiştir. Çalışmanın sonucunda kazanımların anahtar yetkinliklere uyumu, tüm ortaokul sınıflarına (5-8. sınıf) göre ve sınıflar özelinde incelendiğinde “ana dilde iletişim”, “öğrenmeyi öğrenme”, “kültürel farkındalık ve ifade” yetkinliklerinin kazanımlarla en uyumlu yetkinlikler olduğu görülmüştür. Anahtar yetkinlikler ile en uyumlu beceri alanlarının sırasıyla okuma, yazma, dinleme ve konuşma becerisi olduğu tespit edilmiştir. Ayrıca sınıf düzeyleri açısından yedinci sınıf kazanımlarının anahtar yetkinliklerle en uyumlu kazanımlar olduğu, daha sonra sekizinci sınıf kazanımlarının geldiği görülmüştür. Beşinci ve altıncı sınıf kazanımlarının ise eşit sayıda uyumlu olduğu sonucuna ulaşılmıştır. Çalışmanın genel sonucunda ise anahtar yetkinliklerin ortaokul kazanımlarına dengeli bir biçimde dağılmadığı sonucuna ulaşılmıştır.