bluuebunny/crossref_metadata_2025 huggingface dataset:
Gelling, textural, and sensory properties of grass jelly formulated with different starches
Authors: Zhou Shiyun , Meenu Maninder , Xu Baojun
Published: January 2025

Starch from different sources exhibits different properties when used as an ingredient for developing a food. There are many recipes reported to produce grass jellies from different starches. However, the impact of starch from a particular source on the quality of grass jelly has not been explored untill now. Thus, in present study, blume polysaccharide extract from mesona herb was mixed with starch slurries from 14 different sources while boiling to prepare grass jellies. These grass jellies were further investigated for their microstructure, color, cohesiveness, gumminess, hardness, springiness, and chewiness to explore the impact of starch source of grass jellies quality. Among all the starches, the pea starch-based grass jelly presented the highest texture qualities in terms of hardness, gumminess, and chewiness. Whereas corn starch-based grass jelly exhibited higher values for cohesiveness and springiness. Overall, grass jelly formulated with pea and corn starch performed well in terms of texture properties analysis among other samples. The canna grass jelly was the most preferred by panelists in terms of sensory properties. All samples showed to have a network structure under scanning electron microscopy (SEM). The color of all jelly samples was dark and an insignificant difference was observed in color values of all the samples. Based on all parameters discussed in this study, pea starch, corn starch and canna starch are highly preferred for producing grass jelly from Chinese dry mesona herb. As the grass jellies formulated with pea starch, corn starch, and canna starch exhibit improved quality parameters, more studies need to be conducted to further explore the optimal proportion of these starches and herbal extracts as well as their impact on gelation for developing novel grass jellies. In addition, the viscoelastic properties of formulated grass jelly samples also need to be explored to understand addition properties. It is also important to explore the reason behind the high values for the textual properties of pea starch grass jelly compared to 13 other grass jelly samples formulated with different starch sources.

Graphical Abstract
Effect of ketamine on anxiety: findings from the Ketamine for Adult Depression Study
Authors: Mills Natalie T , Nikolin Stevan , Glozier Nick , Barton David , Baune Bernhard T , Fitzgerald Paul B , Glue Paul , Sarma Shanthi , Rodgers Anthony , Hadzi-Pavlovic Dusan , Alonzo Angelo , Dong Vanessa , Martin Donel , Mitchell Philip B , Berk Michael , Carter Gregory , Hackett Maree L , Somogyi Andrew A. , Mihalopoulos Cathrine , Chatterton Mary Lou , Hood Sean , Loo Colleen K.
Published: January 2025

Background

Anxiety disorders and treatment-resistant major depressive disorder (TRD) are often comorbid. Studies suggest ketamine has anxiolytic and antidepressant properties.

Aims

To investigate if subcutaneous racemic ketamine, delivered twice weekly for 4 weeks, reduces anxiety in people with TRD.

Method

The Ketamine for Adult Depression Study was a multisite 4-week randomised, double-blind, active (midazolam)-controlled trial. The study initially used fixed low dose ketamine (0.5 mg/kg, cohort 1), before protocol revision to flexible, response-guided dosing (0.5–0.9 mg/kg, cohort 2). This secondary analysis assessed anxiety using the Hamilton Anxiety (HAM-A) scale (primary measure) and ‘inner tension’ item 3 of the Montgomery–Åsberg Depression Rating Scale (MADRS), at baseline, 4 weeks (end treatment) and 4 weeks after treatment end. Analyses of change in anxiety between ketamine and midazolam groups included all participants who received at least one treatment (n = 174), with a mixed effects repeated measures model used to assess the primary anxiety measure. The trial was registered at www.anzctr.org.au (ACTRN12616001096448).

Results

In cohort 1 (n = 68) the reduction in HAM-A score was not statistically significant: −1.4 (95% CI [−8.6, 3.2], P = 0.37), whereas a significant reduction was seen for cohort 2 (n = 106) of −4.0 (95% CI [−10.6, −1.9], P = 0.0058), favouring ketamine over midazolam. These effects were mediated by total MADRS and were not maintained at 4 weeks after treatment end. MADRS item 3 was also significantly reduced in cohort 2 (P = 0.026) but not cohort 1 (P = 0.96).

Conclusion

Ketamine reduces anxiety in people with TRD when administered subcutaneously in adequate doses.
Changing Landscape of Head and Neck Squamous Cell Carcinoma and Nasopharyngeal Carcinoma Treatment and Survival Trends in Thailand: A 13-Year Multicenter Retrospective Study of Patients
Authors: Ngamphaiboon Nuttapong , Dechaphunkul Arunee , Vinayanuwattikun Chanida , Danchaivijitr Pongwut , Thamrongjirapat Thanaporn , Prayongrat Anussara , Dechaphunkul Tanadech , Jiratrachu Rungarun , Pattaranutaporn Poompis , Jiarpinitnun Chuleeporn , Setakornnukul Jiraporn
Published: January 2025

PURPOSE

The incidence and survival rates of head and neck squamous cell carcinoma (HNSCC) and nasopharyngeal carcinoma (NPC) vary globally, influenced by factors such as ethnicity, lifestyle, and health care systems.

METHODS

A retrospective analysis was conducted on patients with HNSCC treated between 2008 and 2020 in four major Thai academic cancer centers, using a multidisciplinary multicenter database. The study focused on the evolution of patient characteristics, survival changes, and treatment landscape alterations over time.

RESULTS

Among 6,319 patients, the most common primary sites were nasopharynx (33%), oral cavity (23%), oropharynx (17%), larynx (15%), and hypopharynx (8%). An increase in human papillomavirus–related oropharyngeal carcinoma was noted, from 13% in 2008 to 42% in 2019-2020. The majority of patients presented with locally advanced (LA) stages (IVa/b: 50%, III: 26%). Chemoradiotherapy (54%) and surgery (24%) were the main treatments, with cisplatin (79%) being most commonly used in chemoradiation. Overall survival (OS) improved annually across all subsites, correlating with an increase in intensity-modulated radiotherapy (IMRT) use, from 25% in 2008 to 90% in 2019-2020. The median follow-up duration was 4.59 years, with a minimum of 2.75 years. Patients treated with IMRT had significantly longer OS compared with those treated with non-IMRT techniques, in both NPC and non-NPC HNSCC (
P
< .001).

CONCLUSION

To our knowledge, this is the largest study in Thailand that demonstrates increasing survival outcomes in patients with HNSCC and NPC, despite commonly presenting with LA stages. The increasing use of IMRT may be contributing to improved survival outcomes in both patients with NPC and non-NPC HNSCC patients.
Incidence of Cancers in Kerala, India: A Review of Population-Based Registry Data
Authors: Boby Jeffrey Mathew , Varughese Deepak , Benny Jame Mathew , Thomas Mathew , Mathew Aju
Published: January 2025

PURPOSE

Kerala in India leads the nation in both Human Development Index and Sustainable Development Index. The state is a harbinger for the rest of the country in matters of health. Documentation of cancer trends and quantifying the cancer burden is crucial for planning oncology services in the country. In this study, we aim to perform a time series analysis using data from the National Cancer Registry.

METHODS

Data for crude incidence, age-adjusted incidence, and disease-specific incidence were extracted from published reports of the Population-Based Cancer registries at Kollam and Thiruvananthapuram. Data collected between 2006 and 2008 were analyzed and published in 2010. Data collected between 2012 and 2016 were published in 2020. Descriptive statistics was used for analysis.

RESULTS

Age-adjusted incidence rates increased from 121.7 per 100,000 men to 137.8 in Thiruvananthapuram from 2006-2008 to 2012-2016 period. Among women, in Thiruvananthapuram, the age-adjusted rates increased from 108.3 to 127.3. In Kollam, the age-adjusted incidence rate increased from 113.3 to 127.1 among men and 89.7 to 107.1 among women. Lung and breast cancers remain the most common cancers among men and women.

CONCLUSION

There has been an increase in both crude and age-adjusted incidence rates in Kerala. However, these changes are in line with global trends in cancer incidence. Lifestyle changes and reduced tobacco and alcohol use will help decrease the incidence of cancer in Kerala.
Fulvestrant Versus Anastrozole in Endocrine Therapy–Naïve Women With Hormone Receptor–Positive Advanced Breast Cancer: Final Overall Survival in the Phase III FALCON Trial
Authors: Robertson John F.R. , Shao Zhimin , Noguchi Shinzaburo , Bondarenko Igor , Panasci Lawrence , Singh Sandeep , Subramaniam Shankar , Ellis Matthew J.
Published: January 2025

The randomized phase III FALCON trial demonstrated significant improvement in progression-free survival (PFS) with fulvestrant versus anastrozole in postmenopausal women with endocrine therapy–naïve, hormone receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer. Herein, the prespecified final overall survival (OS) analysis is reported. After the primary PFS analysis, data were collected on survival, serious adverse events, and health-related quality of life. The final OS analysis was triggered at ≥65% maturity and ≥8 years since the last patient was enrolled. Analyses were descriptive with nominal
P
values (one-sided α threshold .01845). At the data cutoff (July 11, 2022), 314 (68.0%) of 462 patients had died (fulvestrant, 157/230 [68.3%], anastrozole, 157/232 [67.7%]). The final OS analysis of FALCON demonstrated no significant difference between fulvestrant and anastrozole (medians, 44.8 and 42.7 months, respectively; hazard ratio [HR], 0.97 [95% CI, 0.77 to 1.21];
P
= .7579). Among patients with nonvisceral disease (n = 208), a trend showed a 15% reduction in the relative risk of death with fulvestrant versus anastrozole (median OS, 65.2
v
47.8 months; HR, 0.85 [95% CI, 0.60 to 1.20]). Data from FALCON are consistent with published evidence of long-term clinical benefit with fulvestrant and other endocrine therapies in the subset of patients with nonvisceral disease.
Detecting Early Recurrence With Circulating Tumor DNA in Stage I-III Biliary Tract Cancer After Curative Resection
Authors: Yu James , He Aiwu Ruth , Ouf Mahmoud , Mehta Rutika , Anaya Daniel A. , Denbo Jason , Bridges Catherine , Tin Antony , Aushev Vasily N. , Palsuledesai Charuta C. , Sharma Shruti , Jurdi Adham , Liu Minetta C. , Kim Richard D.
Published: January 2025

PURPOSE

This study aimed to assess (1) the prognostic value of circulating tumor DNA (ctDNA) and (2) the ability of ctDNA to detect recurrence compared with standard surveillance in curatively resected early-stage biliary tract cancer (BTC).

METHODS

This retrospective, multicenter cohort study evaluated serial ctDNA testing for surveillance in patients with early-stage BTC after curative resection. We evaluated the relapse-free survival (RFS) by ctDNA positivity. The sensitivity of ctDNA in detecting a confirmed recurrence of BTC, defined as a biopsy-proven or true progression by radiographic tumor dynamics, was evaluated. The lead time was calculated from the first ctDNA detection to the confirmed recurrence.

RESULTS

A total of 56 patients with curatively resected stage I-III BTC were included in this study, with a median follow-up of 12.8 months from the date of surgery. ctDNA detection during the molecular residual disease window period (median RFS, 6.6 months
v
not reached; hazard ratio [HR], 26 [95% CI, 2.6 to 265];
P
< .0001) and during the surveillance period (median RFS, 19.3 months
v
not reached; HR, 20 [95% CI, 2.6 to 153];
P
< .0001) were associated with poorer RFS. Sixteen patients had confirmed recurrence. ctDNA identified recurrence in 93.8.% (15/16) of the recurred patients with an average lead time of 3.7 months. Carbohydrate antigen 19-9 levels did not show any significant correlation with RFS (HR, 1.17 [95% Cl, 0.24 to 5.71];
P
= .844) in contrast to ctDNA.

CONCLUSION

The findings from our real-world cohort study revealed the (1) promising value of ctDNA as a prognostic biomarker for relapse in curatively resected BTC and (2) potential early detectability of recurrence by ctDNA compared with standard surveillance.
Clinical Outcomes and Molecular Profiling of Pancreatic Acinar Cell Carcinoma: A Retrospective Study
Authors: Eslinger Cody , Seddighzadeh Bobak , Yee Claire , Elsabbagh Zaid , Pai Rish , Hartley Chris , Starr Jason , Bekaii-Saab Tanios , Halfdanarson Thorvardur R. , Sonbol Mohamad Bassam
Published: January 2025

PURPOSE

Pancreatic acinar cell carcinoma (PACC) is a rare and aggressive form of pancreatic cancer that originates in the acinar cells of the exocrine pancreas. In this study, we aimed to investigate the clinical and molecular characteristics of patients with PACC at our institution.

METHODS

This was a retrospective study of patients with PACC seen at Mayo Clinic between 2002 and 2023. Baseline patient characteristics, tumor pathology, treatment strategies used, and survival outcomes were analyzed. Kaplan-Meier curves were estimated using newsurv macros in SAS.

RESULTS

The study included a total of 65 patients with PACC. The median age at diagnosis was 66 years. Almost half of the patients (48%) presented with resectable/borderline-resectable disease (n = 28). Five-year overall survival (OS) for resectable/borderline-resectable, locally advanced/unresectable, and metastatic disease were 72.0%, 21.6%, and 20.9%, respectively. Somatic and germline next-generation sequencing identified numerous potentially actionable targets including homologous recombination (43% somatic, 33% germline),
RAF
alterations (29% somatic), and mismatch repair (14% somatic).

CONCLUSION

Our findings underscore the heterogeneity and aggressive nature of PACC. Despite the improved prognosis for patients with resectable/borderline-resectable disease, OS remains poor, particularly for those with locally advanced or metastatic disease. The identification of actionable molecular targets in a significant proportion of patients highlights the potential for personalized therapeutic approaches. Future research should focus on tailored treatment strategies to exploit these molecular vulnerabilities, which may offer new options for improving outcomes in this rare malignancy.
Reputation mechanisms and cooperative emergence in complex network games: Current status and prospects
Authors: Tang Wei , Yang Hui , Wang Chun
Published: January 2025

This paper comprehensively reviews the research progress on reputation evolution mechanisms within the framework of network-based evolutionary game theory. It first summarizes the typical strategy learning mechanisms used in evolutionary games. Next, it provides an overview of traditional reputation evolution mechanisms and their associated mathematical models, highlighting recent research findings. Furthermore, the paper presents experimental evidence from several key studies, including mechanisms like reputation-based incremental heterogeneity and reputation-based discount accumulation. It identifies the limitations of current research on reputation evolution mechanisms and proposes future research directions. The aim is to empirically verify the role of reputation in promoting cooperative behavior by exploring more accurate reputation evaluation mechanisms and developing reputation evolution models across diverse network structures.
Genotype-Phenotype Correlations in the Hyperparathyroidism-Jaw Tumor Syndrome
Authors: Simonds William F , Li Yulong , Jha Smita
Published: January 2025

Establishing genotype-phenotype correlations in disorders of hereditary endocrine neoplasia is important for clinical screening, genetic counseling, prognostication, surveillance, and surgical strategy, and may also provide clues about disease pathogenesis. Important genotype-phenotype correlations are recognized, for example, in pheochromocytoma/paraganglioma and multiple endocrine neoplasia type 2A. The presence of such correlations has been less clear in other familial endocrine disorders associated with primary hyperparathyroidism including multiple endocrine neoplasia type 1, and the hyperparathyroidism-jaw tumor syndrome (HPT-JT). Characteristic features of HPT-JT, apart from fibro-osseous jaw tumors and uterine lesions, include renal neoplasms, such as Wilms tumor and mixed epithelial and stromal tumor (“renal hamartomas”), and a high incidence of parathyroid cancer. Emerging evidence suggests two different genotype-phenotype correlations in HPT-JT based on the type of variant in the CDC73 tumor suppressor gene. Although multiple CDC73 genotypes can give rise to the Wilms tumor phenotype in HPT-JT, the development of mixed epithelial and stromal tumor of the kidney specifically correlates with the presence of a start-loss variant affecting the initiator methionine codon of parafibromin, the protein product encoded by CDC73. Furthermore, the risk of parathyroid cancer in HPT-JT also appears to correlate with genotype: CDC73 frameshift indel, splice-site, and stop-gain genotypes are associated with a greatly increased risk of parathyroid carcinoma compared to carriers of CDC73 missense and nonframeshift indel variants. The recognition of such genotype-phenotype correlations in HPT-JT may impact genetic counseling, patient care and disease surveillance.
Optogenetic control of cAMP oscillations reveals frequency-selective transcription factor dynamics in Dictyostelium
Authors: Yamashita Kensuke , Shimane Kazuya , Muramoto Tetsuya
Published: January 2025

Oscillatory dynamics and their modulation are crucial for cellular decision-making; however, analysing these dynamics remains challenging. Here, we present a tool that combines the light-activated adenylate cyclase mPAC with the cAMP biosensor Pink Flamindo, enabling precise manipulation and real-time monitoring of cAMP oscillation frequencies in Dictyostelium. High-frequency modulation of cAMP oscillations induced cell aggregation and multicellular formation, even at low cell densities, such as a few dozen cells. At the population level, chemotactic aggregation is driven by modulated frequency signals. Additionally, modulation of cAMP frequency significantly reduced the amplitude of the shuttling behaviour of the transcription factor GtaC, demonstrating low-pass filter characteristics capable of converting subtle oscillation changes, such as from 6 min to 4 min, into gene expression. These findings enhance our understanding of frequency-selective cellular decoding and its role in cellular signalling and development.
A comparison of seasonal flexibility in pectoralis muscle fiber type and enzyme activity in migratory and resident sparrow species
Authors: Lewicki Louisa M. , Zhang Marina , Staples James F. , Guglielmo Christopher G. , Ivy Catherine M.
Published: January 2025

The pectoralis muscle in birds is important for flight and thermogenesis. In migratory songbirds this muscle exhibits seasonal flexibility in size, but whether this flexibility reflects changes in muscle fiber type has not been well documented. We investigated how seasonal changes in photoperiod affected pectoralis muscle fiber type and metabolic enzymes, comparing among three closely related sparrow species: two seasonal migrants and one year-round, temperate climate resident. We quantified fast oxidative glycolytic (FOG) and fast glycolytic (FG) fibers histologically, and measured activities of citrate synthase (CS) and lactate dehydrogenase (LDH) in the pectoralis muscle of the three species that were acclimated to long or short periods of daylight. In all species, FOG was the predominant fiber type, but song sparrows had FG fibers regardless of daylight conditions. By contrast, Lincoln's sparrows incorporated FG fibers only under short-daylight conditions, and house sparrows did not significantly express FG fibers, regardless of daylight length. Both migratory species increased LDH activity in short-daylight conditions but did not alter CS activity. In contrast, resident house sparrows did not alter CS or LDH activity with changes in daylight length. Our findings suggest that the presence of FG fibers is important for seasonal flexibility in LDH activity. Additionally, migratory species exhibited seasonal flexibility in muscle fiber type and enzyme activity, presumably to support migratory flight, while the resident species did not exhibit such seasonal flexibility, suggesting that this consistent phenotype is important year-round, despite changing thermogenic requirements.
Knowledge and attitudes of nurses regarding pain in adults' intensive care units
Authors: Papanikita Maria , Pavlatou Niki
Published: January 2025

Background: Pain is a significant aggravating factor in the adult Intensive Care Unit (ICU). Bibliographically it is usually mentioned as the fifth vital point. Pain in ICUs is difficult to assess due to the health status of the patients admitted to it.
Material and Method: In the present survey a total sample of 63 nursing staff was received by the method of interview. To collect data, an anonymous questionnaire that captures the basic demographics and the questionnaire "Knowledge and Attitudes Survey Regarding Pain" of Ferrell and McCaffery were used. Also, a consent form for participation in the research was distributed as well.
Results: The knowledge score ranged from 27.6 to 82.8 points with a mean of 50.2 points. It appeared to be a statistically significant finding between knowledge of nursing staff and their marital status (p = 0.043) and basic nursing education (p = 0.010). Singles and those with a university degree turned out to have higher knowledge scores.
Conclusion: Lack of knowledge of the nursing staff regarding pharmacology was found. Data gathered in the present study may be useful for the reorientation of
educational programs at undergraduate level and to provide feedback for lifelong programs of employed nurses.
Quality of Life and cost of living in lung cancer patients
Authors: Kiranoudi Aggeliki , Kalogianni Antonia , Kapadochos Theodoros , Kouris Ioannis , Douki Stamatina , Kyriakopoulos Antonios , Toylia Georgia
Published: January 2025

Introduction: Lung cancer accounts for about 34% of cancer deaths in men and 23% in women. Advances in treatment options for lung cancer patients are increasing the survival rate and improving the quality of life.
Aim: To explore the quality of life of lung cancer patients in Greece as well as to estimate the change in their cost of living.
Methods: This is a prospective descriptive observational study. In total, 170 participants were enrolled in the study. Data collection was performed by using a questionnaire of both open-ended and closed-ended questions. Data analysis was performed using SPSS ver. 21.0 (Statistical Package for Social Sciences). 
Results: The mean age of patients was 67.4 years, while 72.4% of patients were male. The majority of the patients (71.2%) were retired and 13.6% were employed. The average cost of living due to the disease during the previous semester was €4.518. Patients with lower total cost of living had better general health (p=0,006). Patients who resided with more people, with higher monthly family income and lower total cost of living, had better mental health (0.016, 0.027, 0043, respectively).
Conclusion: The main goal of the therapeutic approach is the quality of life of cancer patient alongside the effectiveness of the treatment. Determining the factors affecting quality of life that the patient considers important is crucial, with cost of living consisting as one of them. Strategies for reducing the cost of living for cancer patients should be considered.
A Questionnaire Dataset on Perceived Stress in Indian Higher Education Students during Emergency Remote Learning
Authors: Shanbhog M Sharisha , Medikonda Jeevan , Rai Shweta , Charls Mathias Rayan
Published: January 2025

Background The COVID-19 pandemic led to a sudden shift to Emergency Remote Learning, significantly impacting students’ mental health. This study visualizes and analyses various stressors contributing to stress levels among university students during Emergency Remote Learning and explores how different factors from environmental and instructional mediums contribute to their perceived stress. Method Data was collected through a cross-sectional survey using the Modified Perceived Stress Scale and an additional set of 20 Likert scale items on Emergency Remote Learning. One-sample t-tests were performed to assess the consistency of responses across questionnaire items, and correlation analysis was conducted to examine the relationships between different stressors. Frequency distributions were also analyzed to capture the prevalence of stress levels across demographic, environmental, and instructional variables. Conclusion The study revealed that frequent thoughts about unaccomplished tasks were associated with high stress (14.12%). Other factors include feeling nervous and stressed, feeling things that are not going their way, and difficulties piling up significantly elevated stress levels. Items specific to Emergency Remote Learning revealed that a sudden shift to Remote Learning heavily influenced students’ mental well-being. Additionally, demographic analysis showed that students aged 21 experienced the highest stress levels. Living arrangements, internet connectivity, and the impact of COVID-19 on close affinities further contributed to stress. This study underscores the complexity of stress during Emergency Remote Learning. It emphasizes the need for institutions to address psychological and instructional factors to support students better during remote learning environments.
„Stado jełopów”? „Kancelaria w powietrzu”? Krótka historia 318 Dywizjonu Myśliwsko-Rozpoznawczego „Gdański”
Authors: Męczykowski Łukasz
Published: January 2025

318 Dywizjon Myśliwsko-Rozpoznawczy „Gdański” to jedna z najmniej znanych jednostek Polskich Sił Powietrznych w II wojnie światowej i jedyny polski dywizjon działający prawie wyłącznie na terenie Włoch. Sformowany w 1943 r., od początku przeznaczony był do współpracy z 2 Korpusem Polskim. Z racji charakteru pełnionych zadań, jego piloci nie mogli pochwalić się zestrzeleniami czy ilością zrzuconych bomb. Ich „trofeum” były fotografie i cele zniszczone przez współpracującą z nimi artylerię. Choć walczyli tylko przez rok, odcisnęli swe piętno na historii walk podczas II wojny światowej na Półwyspie Apenińskim.
Działania wojenne na terenie Malborka w 1945 r. i kwestia masowego grobu ponad dwóch tysięcy cywilnych ofiar wojny
Authors: Tomkiewicz Monika
Published: January 2025

W czerwcu 1944 r., kiedy Niemcy rozpoczęli przygotowania do obrony Malborka, miasto zostało ogłoszone twierdzą. Ofensywa sowiecka rozpoczęła się 12 stycznia 1945 r. W mieście zorganizowano centralne miejsce koncentracji uciekinierów z Prus Wschodnich, w którym cywilna ludność niemiecka oczekiwała na dalszą ewakuację w kierunku zachodnim. Informacje o zbliżających się do miasta oddziałach armii sowieckiej wywołały panikę wśród mieszkańców i uciekinierów, którzy w pośpiechu zaczęli przemieszczać się dalej. W czasie wędrówki byli świadkami przerażających aktów agresji ze strony żołnierzy sowieckich. Od 27 stycznia do połowy kwietnia 1945 r. Malbork znajdował się pod wyłączną kontrolą i administracją Armii Czerwonej. Prace porządkowe po wojnie trwały przez wiele lat. W październiku 2008 r., podczas prowadzonych prac rozbiórkowo-wyburzeniowych dawnego kina „Włókniarz” przy ul. Solnej (obecnie Sierakowskich) w Malborku, odnaleziono szczątki blisko 2 000 osób. Stało się to podstawą do wszczęcia śledztwa przez Prokuraturę Rejonową w Malborku. Po zakończeniu prac ekshumacyjnych, 22 stycznia 2009 r. śledztwo zostało przekazane do dalszego prowadzenia prokuratorom z Oddziałowej Komisji Ścigania Zbrodni przeciwko Narodowi Polskiemu w Gdańsku. Po zakończeniu w lipcu 2009 r. ich prac odnalezione szczątki cywilnych ofiar narodowości niemieckiej zostały przekazane Radzie Ochrony Pamięci Walk i Męczeństwa. Ostatecznie, 14 sierpnia 2009 r., niemiecka fundacja „Pamięć”, współpracując ze Związkiem Opieki nad Niemieckimi Grobami Wojennymi w Kassel (Volksbund Deutsche Kriegsgräberfürsorge), zorganizowały uroczysty pogrzeb na niemieckim cmentarzu wojennym w miejscowości Glinna, w gminie Stare Czarnowo koło Szczecina.
Narodziny Trójmiasta 1945–1949. Koncepcje i twórcy pierwszego planu Zespołu GD
Authors: Bańkowska Barbara
Published: January 2025

Decyzja o odbudowie kraju ze zniszczeń wojennych i konieczna integracja zmienionego po wojnie terytorium Polski wywołały potrzebę stworzenia nowych zasad przestrzennego kształtowania kraju. Poza koniecznością opracowania planu krajowego wskazano węzłowe zadania planistyczne, do opracowania w pierwszej kolejności. Podstawy odbudowy i rozwoju unicestwionej stolicy miało określić Biuro Odbudowy Stolicy (BOS). Odpowiednikiem BOS-u były Regionalne Dyrekcje Planowania Przestrzennego (RDPP), powoływane we wszystkich województwach. W pierwszej kolejności miano uruchomić plany zespołów portowo-miejskich. Suma tych zadań stała się wielkim wyzwaniem dla nielicznej grupy polskich urbanistów ocalałych po wojnie. Do organizacji RDPP na Wybrzeżu wysłany został znany urbanista warszawski, Stanisław Różański, pełniący funkcję dyrektora tej jednostki w latach 1945–1948. Był on twórcą tezy o jedności zespołu Gdańsk – Sopot – Gdynia. Jedność ta różnie była postrzegana. Władysław Czerny, architekt, urbanista, ówczesny wiceprezydent miasta Gdańska, twórca idei odbudowy Głównego Miasta Gdańska w formule historycznej, chciał rozwijać koncepcję „Wielkiego Gdańska”, który w swoje granice administracyjne wchłonie wszystkie okoliczne miasta łącznie z Gdynią. Michał Kaczorowski ówczesny Minister Odbudowy, przerwał te prace, powołując równocześnie Kamila Lisowskiego na dyrektora Biura Planu GD w ramach RDPP i generalnego projektanta Trójmiasta.
Cmentarze Gdańska (1945–2015) – omówienie rozprawy doktorskiej
Authors: Grabowski Klaudiusz
Published: January 2025

Artykuł jest omówieniem pracy, której celem było ukazanie palety uwarunkowań prawno-administracyjnych, społecznych, architektonicznych oraz demograficznych, pozwalających przeanalizować topografię cmentarną Gdańska na tle zmienionej po II wojnie światowej i w dalszym ciągu przekształcającej się tkanki miejskiej. Poruszony został w niej też aspekt narodowy, czyli kwestia polonizacji miejskich nekropolii, jak i demograficzny, czyli śmiertelność mieszkańców.
Opracowanie poświęcone powojennym cmentarzom gdańskim jest potrzebne, ponieważ dyskusja na ich temat, w tym współczesne dyskursy związane z ich likwidacją, były i są nadal bezpośrednio splecione z polską refleksją na temat niemieckiej przeszłości miasta. Sposób przeprowadzania likwidacji, które swoje apogeum miały na przełomie lat 60. i 70. sprawił, że postrzegane były one jako akty niemal barbarzyńskie. W likwidacji cmentarzy z XIX w. upatrywano przede wszystkim chęci zacierania obecności ludności niemieckiej i zemsty za krzywdy okresu II wojny światowej. Pomijano przy tym powojenne uwarunkowania i to nie tylko mentalne, lecz również gospodarczo-społeczne, prawne, a nawet zamierzenia urbanistyczne zaplanowane jeszcze przez niemieckich architektów pierwszej połowy XX w. Procesy urbanizacyjne, które możemy obserwować od XVIII w., zakładały likwidacje nekropolii i przekształcanie ich od końca XIX w. w parki.
Reflexões acerca da vivência do acadêmico bolsista de nutrição em um hospital público do Rio de Janeiro
Authors: Davel Miana Gomes Larissa , Aracelly Magalhaes de Souza Dayse , Martins Vido Maria da Penha
Published: January 2025

O processo de estagiar é de extrema importância para os alunos de graduação, sendo um momento ímpar para os estudantes da área da saúde, que podem auxiliar os diversos pacientes em suas necessidades. O estágio supervisionado na prática clínica da faculdade de nutrição é exposto por lei há anos, devido a sua grande importância, podendo ser oferecido como estágio obrigatório ou não obrigatório. O presente trabalho visa debater as questões acerca do estágio de nutrição clínica em um hospital público do Rio de Janeiro, com reflexões importantes do momento vivido para o futuro profissional e engrandecimento pessoal, debatendo experiências vividas na rotina hospitalar, além de ações educativas feitas, e o aprendizado acerca do olhar empático com o paciente.
TECENDO BRINCADEIRAS AFRICANAS E AFRO-BRASILEIRAS NA ESCOLA: UMA PROPOSTA PRETAGÓGICA PARA IMPLEMENTAÇÃO DA LEI Nº 10.639/2003
Authors: Silva Samuel Morais , Petit Sandra Haydée
Published: January 2025

A proposta interventiva é resultado de uma pesquisa de mestrado realizada no Programa de Pós-graduação em Educação, na Universidade Federal do Ceará (UFC), na qual tivemos como objetivo utilizar brincadeiras africanas e afro-brasileiras em aulas de recreação como instrumento facilitador para a implementação da Lei Nº 10.639/03, que reformulou a Lei de Diretrizes e Bases - LDB (9.394/96), com o advento das Diretrizes Curriculares Nacionais para Educação das Relações Étnico-Raciais e para o Ensino de História e Cultura Africana e Afro-brasileira.  O lócus de investigação se constitui em uma turma do 4º ano do Ensino Fundamental I, na escola EEIEF 08 de Março. Essa instituição é vinculada à rede municipal de ensino da cidade do Crato, na região do Cariri, Sul do Ceará. Para tanto, realizamos intervenções pedagógicas propositivas e potencializadoras sob aporte da Pretagogia (AUTOR 2, 2015), referencial filosófico-teórico-metodológico inventivo, criativo e artístico, equipado de conhecimento e saber de matriz africana.
A CRIANÇA E SEUS DIREITOS: CENAS DO COTIDIANO DA EDUCAÇÃO INFANTIL EM DIÁLOGO COM OS ESTUDOS DE WALTER BENJAMIN
Authors: da Costa Abreu Alessandra , Araújo Mairce , Bampi Maria
Published: January 2025

O presente artigo tem como objetivo discutir e defender o lugar de autoria das crianças da Educação Infantil, reconhecendo-as como sujeitos histórico-culturais, atores sociais, protagonistas e produtoras de culturas. O texto se desenha a partir dos estudos de Walter Benjamin que apontam que o modo como as crianças leem e interpretam o mundo são pistas para aprender com elas. Para tal, fundamentadas no diálogo com o autor, trazemos duas situações do cotidiano que instigam reflexões sobre como algumas estratégias utilizadas pelas crianças transgridem modos de aprenderensinar, ainda hegemônicos no cotidiano escolar, que nos levam a questionar o respeito aos direitos das crianças. Para tais reflexões destacamos a contribuição da legislação para o currículo da educação infantil, por meio da Constituição Federal de 88 e as Diretrizes Curriculares Nacionais para a Educação Infantil que garante vários direitos educacionais às crianças.  Por fim, problematizamos o quanto a escola precisa se repensar para ser um local em que o ato dialógico aprenderensinar aconteça de uma forma horizontalizada, em que docentes e crianças aprendam e ensinem concomitantemente, como já nos orientava Paulo Freire, e romper com uma concepção pedagógica pautada pela reprodução de modelos pré-estabelecidos, vivências repetitivas que não garantem o lugar de autoria das crianças.
NÓS SABEMOS O QUE PODE UM CORPO?
Authors: Manning Erin , Bocchetti André , Polessa Maçaira Julia
Published: January 2025

Em entrevista, a artista e filósofa canadense Erin Manning situa a questão do corpo no âmbito de suas pesquisas, desde uma aproximação que privilegia a incorporação a partir de uma mirada pós-humanística e processual. Situado em uma ecologia de relações que lhe dá possibilidade, o corpo é pensado a partir do acontecimento e da dança da atenção que se desenrola entre ambos. O que emerge daí é uma análise relacional e atenta às forças mais-que-humanas que, no caso desta discussão, desemboca em um debate acerca do caráter transindividual da incorporação, com ressonâncias na forma de pensarmos a neurodiversidade e a percepção autista, temas centrais na obra de Manning. Ao debater sobre eles, a pesquisadora também situa seus modos de fazer investigativo, assinalando alguns dos movimentos de seu trabalho que desembocam em um modo de compreender e se aproximar da pesquisa-criação e de conceber o próprio espaço de investigação enquanto ambiente criativo e atento às ecologias de existências que o instauram.
CARTAS PARA SENTIPENSAR A POÉTICA NA DOCÊNCIA EM EDUCAÇÃO
Authors: Moraes Battistelli Bruna , Lima Kelly , Da Cruz Melnick Caroline
Published: January 2025

O objetivo deste ensaio teórico é sentipensar a partir da troca de cartas como podemos exercitar uma poética miudinha na docência no campo da educação. Para tanto, acionamos intelectuais, poetas e escritoras/es que nos acompanham nesse processo, e partimos de conceitos como corazonar, sentipensar e pedagogia engajada para nos auxiliar na tessitura deste ensaio que se hibridiza em decorrência das escolhas de escrita que fizemos. O procedimento metodológico que inspirou este processo é o da cartagrafia, ou seja, a troca de cartas para acionar o que pensamos, sentimos e o como vivemos o tema da poética em nossas experiências docentes. É na composição entre as cartas trocadas pelas autoras que analisamos e propomos um certo modo de sentir a poética na docência, partindo da experiência, entendida como aquilo que nos passa, bem como compreendendoo compromisso que precisamos assumir em busca de um fazer poético implicado com a transformação social e com a afronta aos modos acadêmicos hegemônicos e coloniais. A dimensão poética, desta forma, precisa estar pactuada com a descolonização da afetividade e o acionamento de saberes localizados desde a experiência das pessoas envolvidas, ampliando suas possibilidades a partir da conversa entre humanos e não-humanos em suas diferenças.
E SE BRINCAR FOSSE VIVER, E SE VIVER FOSSE ARTE?
Authors: De Sousa Renan Santiago
Published: January 2025

O presente ensaio teórico, realizado a partir da análise da cosmovisão e das manifestações artísticas das(os) Guarani Mbya, busca apresentar características da vida e da educação desse povo originário, que se concentram em uma poética que relaciona o brincar, o aprender, a arte e o viver. Por meio das histórias de Nhanderu, do ritual para identificar o nome verdadeiro, dos bichos de madeira, dos cânticos espirituais e de protesto, dos instrumentos musicais, da cestaria, da pintura corporal e das danças, as(os) Guaranis educam para a ancestralidade, para a autonomia, para a liberdade e para o cuidado. Nesse sentido, vale a pena aprender com elas(es), a fim de modificarmos as características decolonias, capitalistas, uniformizantes e tradicionalistas que ainda perduram na educação.
Ampliación de los BRICS: Transición Energética y Diplomacia Económica de China | BRICS enlargement: energy transition and Chinese economic diplomacy
Authors: Busilli Virginia Soledad , Aguirre Franco Luciano , Fuma Maitén de los Milagros
Published: January 2025

El artículo analiza la ampliación de los BRICS en 2023 en el marco de la diplomacia económica china, contemplando su objetivo de constituir un liderazgo en la transición energética global. Recientemente, los BRICS se han convertido en un espacio relevante para la gobernanza global hacia el desarrollo verde. La incorporación de Arabia Saudita, Egipto, Emiratos Árabes Unidos, Etiopía e Irán es afín a los lineamientos energéticos de política exterior de Xi Jinping.  El trabajo explora la transición energética como eje de la estrategia externa de China y su articulación con las directrices de BRICS. Para ello, analiza sus vínculos bilaterales con los nuevos miembros, incluyendo asociaciones estratégicas integrales, lazos comerciales e iniciativas de inversión. Se argumenta que la jerarquización de estos socios en la diplomacia china ya se observa en el plano bilateral, y que sus ingresos a BRICS promueven el interés chino en un liderazgo multilateral energético.
A Literatura Surda no processo de Letramento Literário: leitura e interpretação das obras Patinho Surdo e Tibi e Joca na sala de aula
Authors: Ramos dos Santos Miriam
Published: January 2025

Neste artigo, visamos analisar o uso da Literatura Surda na escola como uma proposta de Letramento Literário no Ensino Fundamental. Para isso, propomos como obras a serem trabalhadas em sala de aula os livros Patinho Surdo (ROSA; KARNOPP, 2005) e Tibi e Joca (BISOL, 2001). Trata-se de obras de destaque na Literatura Surda brasileira para o público infantil e juvenil. Nelas, surdos são representados não como deficientes, mas sim como sendo diferentes no âmbito linguístico, identitário e cultural. No que tange ao Letramento Literário de crianças e jovens, partimos dos pressupostos teóricos de Soares (2010), Cosson (2014) Coelho (2000), Amarilha (2009) entre outros. Com relação ao surdo, à língua de sinais e à Literatura Surda, recorremos às teorias de Quadros (1997), Karnopp (2006, 2010), Campos e Stumpf (2012), Perlin (2013) etc.  O trabalho com obras literárias que trazem em seu âmago o protagonismo surdo, as representações de vivências de surdos, bem como suas diferenças linguísticas, identitárias e culturais, podem levar os discentes a um Letramento Literário que envolva a inclusão dessas minorias. As atividades com a Literatura Surda na escola abrem caminho para o dizer do surdo sobre si, ter visibilidade e representatividade literária e social.
Concern over rising Neet numbers
Authors: Hayes Derren
Published: January 2025

Experts call for more proactive support for young people not in education, employment or training
Practice examples: Policymakers gain knowledge on early childhood
Authors: Hogg Sally
Published: January 2025

IN SUMMARY

Education programme informs local and national decision makers about early childhood evidence so they can use this knowledge when formulating policy so it has the best chance of delivering impactful change
Practice examples: Preschool Children's oral skills soar thanks to NELI
Authors: Weinstein Nicole
Published: January 2025

IN SUMMARY

Oral language and enrichment programme for nursery-aged children boosts language skills by an additional three months before they start school.
Five solutions for services in 2025
Authors: Owers Mark
Published: January 2025

Consultant Mark Owers summarises key themes to emerge from the recent NCAS conference
Government acts to tackle home education safeguarding blind spot
Authors: Hayes Derren
Published: January 2025

The Children's Wellbeing and Schools Bill includes powers for local authorities to monitor home-schooling and measures to involve schools in welfare decisions but fails to remove reasonable chastisement defence
Unleashing Model Confidence
Authors: Summers Steve , Sharma Kalyan
Published: January 2025

How physical tests can be harnessed to reinforce the power of simulation
Gastrointestinal bleeding due to small bowel metastasis from lung adenocarcinoma: A case report
Authors: Yuan Tian-Yuan , Chen Ying-Xin , Zhao Yan-Ge , Wang Bing , Wang Shao-Xuan
Published: January 2025

BACKGROUND

Lung cancer is the most prevalent malignant tumor in human body, and is characterized by a high level of malignancy. The most common metastatic sites include the liver, bone, brain, and adrenal gland, while lung cancer resulting in gastrointestinal tract metastasis is uncommon.

CASE SUMMARY

A 74-years-old man with lung cancer was hospitalized owing to blood in the stool, The cause was identified as metastasis to the small intestine, and the patient subsequently underwent radical resection of the small intestine tumor. Currently, the overall condition of the patient is good, and undergoing combined chemotherapy.

CONCLUSION

Early intervention in patients with metastatic tumors can significantly improve prognosis.
Integration of rehabilitation and palliative care in cancer management: A futuristic model
Authors: Swarnakar Raktim , Yadav Shiv Lal
Published: January 2025

It explores the integration of rehabilitation and palliative care in cancer management, advocating for a holistic approach that addresses the diverse needs of patients throughout their treatment journey. Traditional cancer care often prioritizes curative interventions at the expense of overall well-being, leading to a fragmented experience for patients. By combining rehabilitation-focused on restoring function and improving physical health-with palliative care-emphasizing symptom management and quality of life-healthcare providers can create a comprehensive support system. The essay highlights the importance of interdisciplinary collaboration among healthcare professionals, as well as the need for education and training to implement this integrated model effectively. Additionally, it addresses potential barriers such as funding limitations and institutional resistance. Ultimately, the integration of these two disciplines represents a critical evolution in cancer care, enhancing patient outcomes and ensuring that individuals receive compassionate, patient-centered support throughout their journey.
Enhancing orthodontic osteodilated arch treatment through comprehensive nursing interventions and cognitive behavioral therapy
Authors: Byeon Haewon
Published: January 2025

Orthodontic osteodilated arch treatment represents a pivotal approach in dental orthodontics to address dental crowding and misalignment. Integrating cognitive behavioral therapy (CBT) into comprehensive nursing interventions (CNI) aims to address these issues holistically. This editorial explores the effectiveness of CBT-based CNI in improving patient outcomes in orthodontic care. Innovations in remote CBT delivery, such as virtual reality, have also shown potential in reducing pain, anxiety, and depression, emphasizing CBT's adaptability in orthodontic settings. The findings underscore the importance of integrating psychological support into orthodontic care to enhance patient adherence, satisfaction, and overall treatment success. The editorial advocates for a holistic approach that combines psychological and physiological care, highlighting the transformative potential of CBT-based interventions in orthodontic treatment.
Grover–Sagnac interferometer
Authors: Schwarze Christopher
			R. , Manni Anthony D. , Simon David S. , Ndao Abdoulaye , Sergienko Alexander
			V.
Published: January 2025

We demonstrate a nontraditional design of the Sagnac interferometer by
replacing the commonly used beam splitter with a linear-optical Grover
multiport. This substitution creates a pole at the origin of the device
parameter space, with an associated resonance in the output intensity. The
structure of this resonance is dictated only by the nonreciprocal portion
of the phase acquired in the Sagnac loop. This property directly results
from adopting the more symmetric and higher-dimensional central scattering
coin, and it allows for a different approach to registering and detecting
the nonreciprocal Sagnac phase. This parameter may be extracted from the
width of a peak or dip in the interferogram, instead of tracing small
changes in power as in traditional Sagnac interferometry. We discuss how
losses affect the system and potential metrological applications.