bluuebunny/crossref_metadata_2025 huggingface dataset:
The deletion of adenovirus E1B-19KD gene enhanced its cell killing ability against lung cancer cell line A549
Authors: Wang Huiyaxin
Published: January 2024

Oncolytic Viruses immunotherapy is one of the most frequently used anti-cancer agents because it can significantly reverse local immune suppression and amplify antitumor immunity. Although drugs were already applied in cancer treatment, a new agent may open a new pathway for developing oncolytic therapy. This study intends to improve the adenoviral vector to increase its killing effect on tumor cells for effective and safe cancer gene therapy. We modified the pDC316 plasmid by adding TERT promoter, E1A, and E1B viral genes through homologous recombination and transfection. Then the virus was reassured of its stability through PCR analysis, Western blot, viral titer assays, and CPE assay. In the result, Ad-E1B 55k virus especially showed strong cytotoxicity of more than 50% of killing efficacy in vivo A549 cells. Cell viability in HepG2 is around 80% while in MRC5 cells, the viability is approximately 100%, which showed a tumor-specificity of the viruses. Moreover, only on day 4 has 20% of the efficacy of E1B 55k virus and the viability quickly returned to normal on the next day, which indicates the relative safety of the modified in MRC5 normal cells. In conclusion, the modified virus may serve as another starting point to design a potentially safer, better efficacy, and specificity in cancer immunotherapy. However, a further test of the vector in animal trials is recommended.
Biological characteristics of NK cells and their application in cancer treatment
Authors: Yu Zhongyong
Published: January 2024

The leading cause of mortality among people is cancer. Traditional medicine, however, has significant dangers and negative effects. Because of its great effectiveness, lack of side effects, and safety, cellular immunotherapy has been utilized extensively in the treatment of malignancies in recent years. While various treatment options have many benefits, they also present unique issues and difficulties. In certain ways, NK cell immunotherapy can make up for these deficiencies. It is not necessary to rely on the patient's distinct immune cells because they may be made from allogeneic cells. Additionally, it can successfully cure the majority of solid tumours, get rid of cancer cells that are resistant to chemotherapy and radiation treatment and metastasis, and enhance the body's immune system, which is the present study's emphasis. As a result, this article begins by introducing the basic traits of NK cells, including traits, uses, activation methods, and how NK cells destroy other cells in an immune response. The use of NK cell therapy in treating different cancers, including hematological malignancies, is then emphasized. Finally, NK cell treatment for cancer development and potential issues are examined. In the future, it will serve as a reference for the treatment of tumours.
Progress in the application of cytokines in lung cancer treatment
Authors: Cai Rui
Published: January 2024

Lung cancer is the most common cancer today and has become the leading cause of cancer death worldwide. Previous common therapy of this disease mainly include surgery, radiation therapy, chemotherapy etc., and the recently most focused solution of immunotherapy, therapy making use of immunity agents such as vaccines, monoclonal antibodies and cytokines. Cytokines, such as gefitinib, the epidermal growth factor receptor inhibitor, and bevacizumab, the VEGF inhibitor, have been widely used in the clinic as targets for the treatment of lung cancer. Another application of cytokines in the treatment of lung cancer is to play the role of biomarkers to provide an important judgment basis for prognosis and diagnosis. However, based on understanding of the advantages and limitations of cytokine therapy, scientists have ceased to make efforts to develop it into a core of the cancer therapy. cytokine’s potential to be combined with other therapies and to play indicative roles in cancer treatment still arouses scientists’ interest. This passage reviews the common treatments of lung cancer and discusses the progress in the application of cytokines as a component of cancer treatment.
Implementation of Green IoT to Achieve Sustainable Environment for Improving Energy Efficiency
Authors:   Assistant Professor, Research Scholar, SCSE, Galgotias University, Gnoida India., Shekhar Aishwarya , Aleem Dr. Abdul ,   Associate Professor, SCSE, Galgotias University, Gnoida India.
Published: January 2024

The Internet of Things (IoT) has emerged as a powerful tool in the pursuit of achieving a sustainable environment. This abstract highlights the key facets of IoT implementation to foster sustainability. IoT's ability to seamlessly connect devices, collect real-time data, and enable intelligent decision-making has revolutionized various sectors, including energy management, waste reduction, and conservation of natural resources. One of the pivotal applications of IoT in sustainability is in energy management. Smart grids, powered by IoT, optimize energy distribution, reduce wastage, and integrate renewable energy sources effectively. IoT-driven sensors and controls in buildings further enhance energy efficiency through automated lighting, heating, and cooling systems, resulting in reduced carbon emissions. IoT's impact extends to waste management by enabling smart bins that monitor and optimize waste collection routes. This minimizes fuel consumption, reduces traffic congestion, and mitigates the environmental footprint of waste disposal. Moreover, IoT-driven sensors in agricultural practices facilitate precision farming, optimizing resource utilization and minimizing environmental impact. Natural resource conservation is another realm where IoT plays a pivotal role. Smart sensors and remote monitoring devices enable real-time tracking of water quality, air pollution levels, and forest health. This data empowers policymakers and environmentalists to make informed decisions, mitigating the consequences of environmental degradation. To achieve a sustainable green environment through IoT, it's essential to consider data privacy, security, and interoperability between devices and systems.
A Study on the Software Development Life Cycle–Waterfall Model at a Aviation Management Consultant
Authors:   D Y Patil B School, Tathawade, Pune (Maharashtra), India., Kayande Prof. (Dr.) Pranav S , Phadnis Mr. Sidharth ,   Business Systems Analyst and Scrum Master, Real Page Inc, Pune (Maharashtra), India.
Published: January 2024

We have selected the study of software development life cycle- waterfall model, herein after is referred to as SDLC for brevity purpose. We have been allowed to study in the software firm - Aviation Management Consultants. The researchers studied the software named –“Routonomics” developed by the firm. The software enables the airlines to prepare the business plan with 5 years perspective. The purpose of selection of this subject is that SDLC- Waterfall Model is the reference model of any software related work. Many SDLC models evolved from this basic concept. Further, the firm introduced a small change in one of the reports to enable us to understand the practical perception of the SDLC. The researchers were involved in the simulated development of small change in the report.
Artificial Intelligence in Project Management: A Study of The Role of Ai-Powered Chatbots in Project Stakeholder Engagement
Authors:   Department of Project Manager, Great River HealthSystem, Burlington, Iowa (United States of America (USA)., Joshi Herat
Published: January 2024

Artificial Intelligence (AI) is increasingly becoming a cornerstone in the evolution of project management. Its capabilities extend beyond simple automation, fostering improved decision-making processes and enhancing collaborative efforts. Among the various AI tools available, chatbots stand out as particularly transformative for project management. This study delves into the role of AI-powered chatbots in project stakeholder engagement, a critical aspect of successful project management. Chatbots, powered by sophisticated AI algorithms, can provide continuous support and interaction with project stakeholders. This is particularly vital in managing complex projects where continuous communication and prompt responses can significantly influence project success. The study examines how these AI-driven chatbots facilitate stakeholder engagement, focusing on key benefits such as improved communication, increased stakeholder satisfaction, and better overall project outcomes. Through a detailed analysis, we have identified that chatbots enhance communication by offering stakeholders immediate, personalized responses, thereby reducing response times and improving the efficiency of information exchange. This immediacy and personalization contribute to heightened stakeholder satisfaction, as stakeholders feel their concerns and queries are addressed promptly and effectively. Furthermore, our findings suggest that these improvements in stakeholder engagement directly correlate with enhanced project outcomes, including better adherence to timelines, improved project quality, and increased likelihood of meeting project objectives. However, the deployment of chatbots in project management is not without its challenges. One significant hurdle is the need for advanced natural language processing (NLP) capabilities. Effective chatbots must understand and process complex human language nuances to interact effectively with stakeholders. Another challenge observed is the potential for chatbots to become disruptive or annoying. This can occur when chatbots fail to provide relevant or accurate information, or when their interaction style does not align with stakeholder expectations. In conclusion, AI-powered chatbots hold substantial promise for revolutionizing stakeholder engagement in project management. While they present remarkable benefits in improving communication, stakeholder satisfaction, and project outcomes, there are challenges that need to be addressed. These include enhancing NLP capabilities and fine-tuning the interaction style of chatbots to suit diverse stakeholder groups. With these improvements, AI-powered chatbots could significantly contribute to the success of various projects, marking a new era in project management where AI plays a pivotal role in stakeholder engagement and overall project success.
FREQUENCY OF HYPOGLYCEMIA IN NEWBORN WITH BIRTH ASPHYXIA
Authors: AHMAD Z , KHAN IU , SHEHZAD A
Published: January 2024

Birth asphyxia is a significant health concern in Pakistan, often leading to severe complications that contribute to long-term morbidity and mortality in neonates. Understanding the frequency and associated factors of hypoglycemia, a common complication in neonates with birth asphyxia, is crucial for improving neonatal care and outcomes. This study aimed to determine the frequency of hypoglycemia in neonates with birth asphyxia and to explore its association with residential and socioeconomic status. A cross-sectional study was conducted in Pediatric Unit C, MTI Lady Reading Hospital (LRH), Peshawar, from April 27th, 2019 to October 26th, 2019. The study received approval from the hospital's ethical committee. Using a non-probability sampling technique, 141 neonates, aged up to 72 hours and diagnosed with birth asphyxia, were enrolled. The frequency of hypoglycemia among these neonates was observed and recorded. Data analysis was performed using the Statistical Package for the Social Sciences (SPSS), version 23. The study findings revealed a significant association between hypoglycemia and both residential and socioeconomic status in neonates with birth asphyxia. Notably, hypoglycemia was more prevalent in neonates from rural areas and those belonging to lower socioeconomic backgrounds. Hypoglycemia is a common complication in neonates with birth asphyxia, with a higher incidence observed in rural areas and among lower socioeconomic groups. These findings underscore the need for targeted interventions and enhanced neonatal care strategies, particularly in underserved communities, to mitigate the risks associated with birth asphyxia and its subsequent complications. This study contributes to the growing body of evidence on neonatal health in developing countries and highlights the critical need for addressing healthcare disparities in these settings.
Home and School Relationship: Role to Kindergarten Pupils’ Developmental Domains
Authors:   https://orcid.org/0009-0004-2838-4189 johnrobert.agulto@deped.gov.ph Department of Education, Division of Pampanga, Vizal Sto Cristo Elementary School, Vizal Sto Cristo, Candaba, Pampanga, 2013, C. Agulto John Robert
Published: January 2024

This study explores the impact of home and school relationships on the developmental domains of kindergarten pupils in the Municipality of Candaba during the implementation of modular distance learning for School Year 2021 – 2022. Employing an explanatory sequential mixed methods design with 44 teachers and 591 parents as respondents; the findings indicate consistent parental and teacher involvement in kindergarten pupils’ learning. Parents strongly affirmed their children’s mastery across various domains including gross motor, fine motor, self-help, receptive language, expressive language, cognitive, and social-emotional. The study concludes that a significant correlation exists between home and school relationships and kindergarten pupils’ mastery of learning domains. Specifically, an increase in the level of home and school relationships, concerning both teachers’ and parents’ involvement, corresponds to an elevation in the kindergarten pupils’ proficiency across learning domains. Keywords: Home and School Relationship, Modular Distance Learning, Learning Domains, Teachers’ Involvement, Parents’ Involvement
The Proficient Teacher as a Researcher: Drivers, Barriers, and Research Skills
Authors:   https://orcid.org/0000-0003-4861-5840 larry.roallos@deped.gov.ph Department of Education, Batangas, Philippines, M. Roallos Larry
Published: January 2024

There exists a prevailing expectation that educators should assume the predominant responsibility for spearheading research initiatives at the school level. Regrettably, the involvement of teachers in action research is notably scarce, and establishing a research-centric culture proves to be a formidable challenge. An analysis of research endeavors within the Ibaan District illuminates that a paltry percentage of elementary educators (less than ten percent) have undertaken research endeavors. This statistic underscores the exigency for refresher courses to revitalize motivation and instigate active participation in this pedagogical undertaking. Consequently, the present research endeavors to proffer a meticulously designed training framework predicated upon an exhaustive evaluation of teachers’ motivational levels, encountered challenges, research proficiency, and interconnectedness with diverse teacher profile variables. This research utilized a descriptive research design with a survey questionnaire as the data-gathering instrument. One hundred thirty-six randomly selected proficient teachers were the respondents of the study. Results showed that the teachers had inadequate experience in research writing since their employment at DepEd but mostly attended research training, had full-time teaching, and attended lower-level research forums. These teachers were highly motivated in research as a career responsibility, although they were moderately motivated by their growth of knowledge and skills upon doing research. For them, time constraints are a moderate barrier to conducting research. As to research skills, they were moderately skilled in facilitating the validation and reliability testing of the research instrument and in identifying and using appropriate statistical tools. The chi-square test bared that there is a significant relationship between the teachers’ level of motivation and the number of research studies they made, which suggests that more research conducted leads to higher motivation in engaging in research. The proposed training design integrates sessions on enhancing the teachers’ motivation and research skills. Keywords: action research, research motivation and skills, descriptive survey, Philippines
Local Green Marketing Business Environmental Regulatory Framework for Bataan MSME Food Processing: Consultative Development Process
Authors:   https://orcid.org/0000-0002-8956-3576 atdelarosa@bpsu.edu.ph Bataan Peninsula State University Bataan, Philippines, A. Tuazon -Dela Rosa Adona
Published: January 2024

The overarching goal of this exploratory sequential mixed methods design is to evaluate the environmental practices of specific small and medium enterprises (SMEs) in Bataan, Philippines, with a focus on green marketing aspects such as raw material usage, energy consumption, water conservation, waste management, air emissions, and wastewater treatment. Additionally, the study investigates the degree of public involvement in formulating regulations related to green marketing. Respondents, comprising business owners and local government officials, were chosen through a two-step cluster sampling method for quantitative analysis and purposeful sampling for qualitative insights. More so, it revealed a consistent implementation of environmentally friendly practices and green marketing management among SMEs. Interviews with business owners and local government officials yielded positive responses regarding the development of local green marketing policies, particularly for businesses in the food processing sector. Through the analysis and interpretation of collected data, the study provided valuable insights guiding the formulation of a regulatory framework for green marketing. Keywords: green marketing, environmental performance, environmental management, food processing, micro small medium enterprises, eco-labeling policy.
Soft Skills and Sales Performance of Life Insurance Agents in Tagum City
Authors:   https://orcid.org/0009-0004-7239-6371, https://orcid.org/0000-0001-7626-1854, https://orcid.org/0009-0006-2865-6935 marsonmuegna06@gmail.com, elealehsuan.kcast@gmail.com, judeosorio.jude@gmail.com Kapalong College of Agriculture, Sciences and Technology Maniki, Kapalong, Philippines, E. Muegna Marson , G. Suan Elealeh , P. Osorio Judelyn
Published: January 2024

This study explores the significant relationship between soft skills and the sales performance of life insurance agents in Tagum City. The findings contribute to existing knowledge in the literature by shedding light on the connection between soft skills and sales performance among these agents. Utilizing a quantitative approach with a descriptive correlational method, the study employed correlation techniques to characterize existing traits. The 87 life insurance agents in Tagum City who participated in the study demonstrated a high level of soft skills, encompassing communication, problem-solving, leadership, teamwork, and interpersonal skills. Similarly, their sales performance, measured in terms of self-efficacy, competitiveness, performance, and effort, was also notably high. Significantly, the study revealed a strong and statistically significant relationship between soft skills and sales performance among life insurance agents in Tagum City. The implications suggest the importance of prioritizing developing and refining soft skills for employees in this industry. Keywords: life insurance agents, quantitative research, sales performance, soft skills, Philippines
Gender Representation In General Education (GE) Modules
Authors:   https://orcid.org/0009-0003-8718-5017, https://orcid.org/0000-0003-3345-7659 jeaniemarieabudainog@gmail.com, royojames07@gmail.com Kapalong College of Agriculture, Sciences and Technology Maniki, Kapalong, Davao del Norte, Philippines, A. Inog Jeanie Marie , C. Royo James
Published: January 2024

This qualitative discourse analysis and a corpus-based study analyzed the processes employed in embedding male and female characters in General Education (GE) Modules in the local college of Kapalong College of Agriculture, Sciences, and Technology. This study aimed to ascertain the processes of both opposite genders utilizing the Eight-Factor Procedure in Gender Discrimination as adapted from Amerian and Esmaili (2015). Results have shown that there was gender bias in text and images. Gender and linguistic bias were evident due to the repeated imbalance of representations in both opposite genders. With these findings, the researcher has seen the need for a more gender-inclusive curriculum that can raise consciousness and awareness in observing gender-fair language in designing educational materials to be used by teachers and learners in the new normal. Keywords: discourse analysis, gender representation, qualitative study, Philippines
A Qualitative Inquiry On Juvenile Delinquency: Basis For Intervention
Authors:   https://orcid.org/0009-0003-0631-6946, https://orcid.org/0009-0000-8395-8510, https://orcid.org/0009-0003-7518-334X, https://orcid.org/0009-0000-6281-864X juliusramillete8@gmail.com, joan.ramirez090499@gmail.com, jazexcute99@gmail.com, johnmarkpoquita0@gmail.com Kapalong College of Agriculture, Sciences and Technology Maniki, Kapalong, Philippines, S Ramillete Julius , R Villarosa Joan , F. Permangil Jayson , C. Poquita John Mark
Published: January 2024

Juvenile delinquency is a nationwide concern, including in Asuncion and Davao del Norte. This study aims to understand the challenges faced by juveniles in this undertaking aimed at the reasons for their engagement, challenges experienced, and potential interventions. Utilizing a qualitative research design, specifically phenomenology, with a descriptive approach, six juvenile delinquents from Asuncion were interviewed. The findings revealed that peer pressure, socioeconomic factors like poverty, unemployment, and the prevalence of vices, as well as unfavorable home conditions, contribute to juvenile delinquency. Mental factors such as addiction to online games and overconfidence were also identified. Proposed interventions include campus security and youth engagement programs to address peer pressure, employment, and livelihood services for socio-economic factors, and educational programs and family strengthening initiatives for home conditions. Additionally, individual counseling, cognitive-behavioral interventions, and family integrative transition are suggested for mental factors. Future studies should explore the relationship between adolescents and their parents or guardians, as this was identified as a significant factor in preventing juvenile delinquency. Keywords: juvenile delinquency, interventions, peer pressure, socio-economic factors, home conditions, mental factors
Gender and Equality towards Policy Enhancement: A Phenomenological Inquiry on the Stories of LGBTQIA+ Cohabiting Couples
Authors:   https://orcid.org/0009-0007-5098-0755, https://orcid.org/0009-0008-8636-285X, https://orcid.org/0009-0007-2102-4625, https://orcid.org/0009-0007-6127-0628, https://orcid.org/0009-0009-7735-2163, https://orcid.org/0000-0001-6817-1971, https://orcid.org/0009-0004-6722-441X, V. Ramos Reyter Icom , G. Abaño James Cedric , G. Manlapaz Ryan Mark , M. Rollorata Ervic , S. Ulzame Sel , A. Gementiza Linagyn , Q. Poliquit Letty ,   icomramos09@gmail.com, jamesabano18@gmail.com, rhayhassetgenteronezapalnam@gmail.com, ervicrollorata@gmail.com, jieselulzame17@gmail.com, linagyn24.kcast@gmail.com, lettypoliquit@gmail.com Kapalong College of Agriculture, Sciences and Technology Maniki, Kapalong, Philippines
Published: January 2024

This qualitative research, utilizing a phenomenological approach, delved into the experiences of 14 LGBTQIA+ cohabiting couples in Asuncion and Kapalong. The study aimed to uncover challenges, coping mechanisms, and insights regarding social acceptance, inspiring policymakers to create more LGBTQIA+-friendly policies. The findings highlighted difficulties in societal and familial acceptance, with couples facing issues like religious and moral conflicts, discrimination, exclusion, and social stigmatization. Coping strategies included accepting others’ perceptions, making adjustments, fostering communication, and holding onto love. The study showcased the resilience of these couples, providing a foundation for enhanced policies. Keywords: LGBTQIA+, cohabiting couples, social acceptance, lived experiences
Teacher Characteristics and Attitudes in Learning Mathematics as Perceived by Mathematics Teacher Education Students: A Mixed Method Study
Authors:   https://orcid.org/0009-0002-1485-2637, https://orcid.org/0000-0003-1148-2706 ricosuson0504@gmail.com, jobelle.jajalla@kcast.edu.ph Kapalong College of Agriculture, Sciences and Technology Maniki, Kapalong, Philippines, O. Suson Rico , B. Jajalla Jobell
Published: January 2024

This study employed a mixed methods design, utilizing a parallel convergent approach to explore the quantitative status and lived experiences of Mathematics major students regarding their perceived teacher’s characteristics and attitudes. The participants were Mathematics education students, with 80 respondents for the quantitative phase and 14 for the qualitative phase, selected through total enumeration and purposive sampling, respectively. The quantitative results indicated a very high status of perceived teacher characteristics and students’ attitudes. A positive low correlation (r = .27, p = .0064) was found between the two variables. In the qualitative phase, students revealed positive experiences with instructors, emphasizing their good qualities and influence on learning, while also highlighting teacher-related difficulties. Student insights emphasized the crucial role of fair treatment and interaction in learning, predictors of learning attitudes, and the significance of positive attitudes. Notably, the quantitative data largely aligned with the qualitative findings. Keywords: attitude in learning mathematics, mathematics, mixed methods, teacher’s characteristics, Philippines
EDUCAÇÃO AMBIENTAL E DIREITOS HUMANOS: UMA RELAÇÃO INDISSOCIÁVEL
Authors: Serpa Paulo Roberto
Published: January 2024

Esta produção trata-se de uma pesquisa de cunho qualitativo onde se discute a relação indissociável entre a Educação Ambiental – EA e os Direitos Humanos - DH, observando, a EA como princípio essencial dos direitos humanos. Para esta pesquisa, ainda foi realizada uma revisão sistemática de literatura, com o objetivo de investigar o que dizem as pesquisas entre 2012 e 2022 sobre a relação entre a educação ambiental e os direitos humanos. Como resultados, foram selecionados 6 trabalhos, sendo 4 artigos científicos e 2 teses de doutorado que direcionam seus olhares para a formação dos sujeitos em direitos humanos, essencial para o exercício da cidadania e, a educação ambiental como dimensão que potencializa a observação destes ao meio ambiente, a sustentabilidade socioambiental e a vida em sua plenitude.
EXPERIMENTANDO A ECOMOTRICIDADE NA EDUCAÇÃO INFANTIL
Authors: Serpa Paulo Roberto
Published: January 2024

Este trabalho, apresenta-se sob a organização de um relato de experiências sobre a prática docente do pesquisador, onde estabelece o movimento de fundamentar a prática pedagógica realizada das aulas de Educação Física na Educação Infantil. Como problemática desta produção, tem-se o seguinte questionamento: realizar as aulas de Educação Física em ambiente natural é importante para o desenvolvimento da criança? Para ajudar a responder esse questionamento foram elaborados os seguintes objetivos: pesquisar sobre a ecomotricidade; refletir sobre a realização das aulas de Educação Física em ambiente natural, e se, isso é importante para o desenvolvimento da criança; relatar de forma sucinta como são desenvolvidas as práticas nas aulas de Educação Física.
A INFLUÊNCIA DA PANDEMIA DA COVID-19 NOS PROCEDIMENTOS CIRÚRGICOS DE EMERGÊNCIA E URGÊNCIA
Authors: De Azevedo Ricardo Mesquita , Matos Lourdes Yara Araújo , Da Costa Ruth Silva Lima
Published: January 2024

A pandemia global de COVID-19, causada pelo vírus SARS-CoV-2, provocou alterações significativas nos serviços de saúde em todo o mundo. As preocupações quanto à capacidade do sistema de saúde e o receio da exposição ao vírus resultaram em desfechos adversos para indivíduos gravemente enfermos. Objetivo: descrever a influência da pandemia de COVID-19 sobre os procedimentos cirúrgicos de emergência e urgência. Método: Trata-se de uma revisão integrativa da literatura com abordagem descritiva. A coleta dos dados foi realizada por meio dos bancos de dados: Scientific Electronic Library Online (SciELO), National Library of Medicine (PubMed) e Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) pulicados durante o período compreendido entre 2020 e 2023. Resultados: A pandemia de COVID-19 causou impactos significativos na cirurgia de emergência globalmente, manifestando-se em uma notável queda no volume de procedimentos cirúrgicos, ao mesmo tempo em que observou-se um aumento nas complicações e na taxa de mortalidade. Restrições de saúde pública, incluindo bloqueios, comprometeram o acesso aos serviços cirúrgicos de emergência. A apendicite destacou-se como uma preocupação persistente, especialmente em casos com admissões tardias associadas a maior complexidade. A redução nas visitas ao serviço de emergência por pacientes cirúrgicos e a diminuição nas apresentações de emergência abdominal aguda indicam mudanças substanciais nos padrões de busca por atendimento médico urgente durante o período pandêmico. Considerações Finais: A pandemia trouxe desafios significativos para a cirurgia de emergência, refletidos na redução de intervenções, aumento de complicações e mudanças nos padrões de busca por atendimento. A adaptação de estratégias de saúde pública é crucial para enfrentar essas transformações e aprimorar a resposta a futuras emergências médicas.
PRÁTICA COLABORATIVA E TAXONOMIA DE BLOOM: INTEGRAÇÃO DAS TECNOLOGIAS NA IMPLEMENTAÇÃO DA PRÁTICA COLABORATIVA NA EDUCAÇÃO BÁSICA
Authors: Meroto Monique Bolonha das Neves , De Araujo Camila Sabino , Loures Débora Alves Morra , De Carvalho Ianan Eugênia , Da Silva Laila Cristina Nascimento , Santos Silvana Maria Aparecida Viana , Gusmão Yanara Alves , Da Silva Romézio Alves Carvalho
Published: January 2024

Este estudo investigou a fusão de tecnologias e práticas pedagógicas ativas no contexto educacional, visando aprimorar o cenário atual da educação. O principal objetivo era examinar as várias facetas dessa fusão e determinar seu efeito no processo de ensino-aprendizagem. A abordagem metodológica incluiu a revisão de literatura essencial na área de educação, com ênfase em pensadores como Freire, Piaget, Vygotsky, além de pesquisas modernas sobre práticas pedagógicas ativas e tecnologias na educação. Os achados da pesquisa apontaram que a combinação eficaz dessas tecnologias e práticas resultou em um cenário de aprendizado mais cativante e eficiente, fomentando o envolvimento dos estudantes, autonomia, raciocínio crítico e cooperação. Entretanto, foram identificados desafios significativos, incluindo a necessidade de modificar o currículo, aperfeiçoar a formação dos educadores e adaptar os métodos avaliativos. Em conclusão, o estudo sublinha a necessidade de uma estratégia educacional que culmine em um um impacto positivo na educação, evidenciando a importância de inovações pedagógicas no contexto educacional contemporâneo.
EXPLORANDO HORIZONTES EDUCACIONAIS: O IMPACTO DA REALIDADE AUMENTADA NO ENSINO MODERNO
Authors: Gallo Solange Aparecida , Santana Alexandre Jesus Serrat , Brandão Eliezer Lemos , De Carvalho Ianan Eugênia , Paniago Larissa Almeida Ferreira , Meroto Monique Bolonha das Neves , Da Silva Romézio Alves Carvalho , Santos Silvana Maria Aparecida Viana
Published: January 2024

Esta investigação qualitativa, fundamentada em um levantamento bibliográfico, dedica-se à análise da aplicação e impacto da Realidade Aumentada (RA) no âmbito educacional. O objetivo geral é investigar a implementação da RA e seus efeitos no contexto educativo. O estudo possui objetivos específicos que se articulam em três eixos: inicialmente, aborda-se a capacidade da RA de elucidar e simplificar conceitos complexos em ambientes educacionais, sugerindo uma abordagem pedagógica inovadora que ultrapassa os métodos tradicionais de ensino. Posteriormente, analisa-se o impacto da RA no engajamento e motivação discente, examinando como esta tecnologia pode fomentar um aprendizado mais ativo e participativo. Finalmente, a pesquisa enfoca no desenvolvimento de soluções inovadoras para os desafios vinculados à incorporação da RA na educação, identificando obstáculos práticos e formulando estratégias para sua superação. Os resultados indicam que a RA possui um potencial substancial para enriquecer o processo educativo, proporcionando experiências de aprendizado dinâmicas. Através da visualização tridimensional de conteúdos abstratos, a RA contribui para a facilitação da compreensão e memorização de informações. Observa-se também que a RA pode incrementar significativamente o engajamento e a motivação estudantil, promovendo maior interação e colaboração em sala de aula. Pode pressupor-se que, a despeito de alguns desafios técnicos e práticos, a integração eficaz da RA no ambiente educacional tem o potencial de transformar de maneira significativa os processos de ensino e aprendizagem. Assim, a RA se estabelece como uma ferramenta pedagógica robusta, capaz de oferecer experiências educacionais imersivas, em consonância com as necessidades e expectativas dos estudantes do século XXI.
ABORDAGENS INOVADORAS DE ENSINO PARA ESTUDANTES COM AUTISMO: ADAPTAÇÃO E APLICAÇÃO NO AMBIENTE EDUCACIONAL
Authors: Portella Alline Soares de Oliveira , Rangel Ana Bárbara , Da Silva Daniela Fernandes Firmo , Santos Creuza Brandão da Silva , Pinto Carmen Lucia Almeida , Barth Lia da Silva , Ribeiro Sirlene da Silva , Lima Ediana Bernardo Teles
Published: January 2024

Este estudo delineia métodos inovadores de ensino para estudantes com autismo, focando nas adaptações e aplicações em ambientes educacionais. A natureza complexa da desordem do espectro autista (ASD) requer técnicas de ensino que se adaptem às necessidades individuais, permitindo a melhor assimilação do currículo escolar. Adaptações pedagógicas, como a inclusão de suportes visuais e a alteração do ambiente de aprendizagem, demonstraram melhorar os resultados educacionais desses alunos. Este estudo explora ainda a aplicação de tecnologias assistivas em sala de aula, como tablets e aplicativos educacionais, que podem auxiliar a aprendizagem ao permitir a personalização do material didático. O estudo enfatiza a importância da formação adequada de professores no uso dessas estratégias de ensino, bem como a integração de suporte multidisciplinar abrangendo terapeutas ocupacionais, psicólogos e fonoaudiólogos. Conclui-se que, embora possa haver desafios na implementação dessas abordagens, uma educação inclusiva e adaptativa para alunos com autismo é não só possível, mas imperativa para maximizar seu potencial acadêmico e social.
EFL Students' Perceptions of E-learning Tools’ Effects on Students’ Engagement in English Speaking Skill Online Classes
Authors: Pham Ngoc Kim Tuyen , Huynh Trang , Tran Vo Minh Quan , Pham Nguyen Nhat Phuong , Ho Hoang Tin , Nguyen Le Hoang Khang
Published: January 2024

This paper aims to explore Vietnamese students' perceptions of the effects of e-learning tools on student engagement in English-speaking skills online classes. With a survey design and a mixed-method approach, the study investigated 100 participants, including sophomores and juniors, at the Faculty of English Linguistics and Literature, the University of Social Sciences and Humanities, Vietnam National University of Ho Chi Minh City. Descriptive statistics and qualitative data gleaned from a questionnaire and 10 semi-structured interviews were analyzed using SPSS and thematic analysis. Findings show e-learning tools enhance student engagement by facilitating speaking discussion, evoking comfort, and contributing to students’ investment in the tasks. On the contrary, e-learning tools hinder student engagement by causing boredom, stress, and distraction. The study results suggest pedagogical implications for teachers in the design of more engaging English-speaking online lessons. Further, faculty and school leaders can consider the research findings when revising and updating their curriculum to meet the increasing demands of online learning and teaching, with learners' engagement as the centrality. Future research can delve more into inferential statistics on the effects of online classes on students' engagement in English speaking, listening, reading, or writing skills.
Unlocking ESP Learners’ Leadership and Higher-Order Thinking Skills through Whatsapp Community of Practice
Authors: Muniandy Jayanthi , Ramaya Subathira Devi
Published: January 2024

This study investigates the relationship between the WhatsApp group, an instant messenger application as a community of practice platform (knowledge management, regular interactions, ease of using technology, and sense of belonging) and English for Specific Purposes (ESP) learners’ leadership and higher-order thinking (HOT) skills. The current study also examines how participation in the community of practice through the WhatsApp group can enhance leadership and HOT skills for male and female learners. 197 ESP learners participated in the five-point Likert scale questionnaire. The SPSS-AMOS analysis showed that knowledge management, regular interaction, and a sense of belonging significantly enhance learners’ leadership and HOT skills. The results also showed that male learners increased their leadership skills while female learners excelled in the HOT skills by the WhatsApp community of practice. This study has significant educational implications, particularly in emphasizing essential measures when developing an ESP curriculum to prepare learners for their future careers
Тенденції розвитку ринку молока в Україні
Authors: Донець Л. Я. , Родіна О. В. , Курбацька Л. М.
Published: January 2024

Для українського ринку молока, як і для більшості ринків агропродовольчої продукції з початком військово агресії змінилися правила гри на внутрішньому і зовнішньому ринках. Молоко є одним із продуктів харчування та сировиною, яка забезпечує певний рівень продовольчої безпеки в країні. За останні десятки років молочна галузь стикнулася із проблемами, такими як скорочення поголів'я великої рогатої худоби, зменшення обсягів виробництва молока та втрата позицій на внутрішньому ринку (дисбаланс між попитом і пропозицією). Тому у сучасних умовах нестабільної економічної та політичної ситуації в Україні, коли ринок стає не лише площиною обміну товарів, але й стратегічно важливим ланцюгом постачання продуктів харчування, аналіз стану ринку молока стає важливою задачею. За результатами проведеної оцінки з’ясовано ряд основних тенденцій (негативних, позитивних), які склалася на ринку молока. Моніторинг показав, що більша частина молока виробляється господарствами населення, тому необхідно розглянути одним із пріоритетних напрямків – це державну підтримку основних виробників молока на ринку та створення умов і можливостей для підтримки поступової трансформації у молочні кооперативи. На основі проведених досліджень та для стабілізації ситуації запропоновано комплексний підхід, включаючи економічну підтримку, вдосконалення правового середовища для регулювання ринку молока та державну підтримку для сприяння збільшення обсягів виробництва молока. Тільки такий підхід може сприяти покращенню ситуації та створенню стійкої та конкурентоспроможної молочної галузі в Україні. Перспективами подальших наукових досліджень є оцінка впливу запропонованих напрямків на ефективність функціонування ринку молока в Україні. Тип статті – емпірична.
PERENCANAAN LABA UMKM BUBUR AYAM PASUNDAN
Authors: Tahol Triana Olivia , Putri Azizah Fitriyah Maharani  , Maghfiroh Hikmatul , Adiyanto Mochamad Reza
Published: January 2024

This research focuses on elucidating the intricacies of sales planning with a particular emphasis on achieving the desired profit levels through the utilization of Break Even Point (BEP) and Cost of Goods Sold (HPP) analysis. Employing a descriptive qualitative approach, this study leverages semi-structured interviews as the primary method for data collection, specifically targeting small-scale entrepreneurs as the key informants. The primary objective is to provide a comprehensive understanding of the challenges and opportunities associated with sales planning in the context of achieving optimal profit margins. The findings of this research reveal a monthly loss of -2,831,000, prompting a critical examination of the existing business model. To attain a desired income margin of 50%, it is determined that an increase in sales volume is imperative. Specifically, selling 387 portions per day at a price point of 16,986 per portion is identified as the strategic approach to offsetting losses and achieving the targeted profit margin. This insight underscores the importance of meticulous planning and strategic decision-making in the realm of sales management. Furthermore, the analysis of Break Even Point (BEP) and Cost of Goods Sold (HPP) emerges as a pivotal tool for entrepreneurs in crafting effective profit plans. The simplicity of the calculations employed in this study is highlighted as a practical advantage, enabling entrepreneurs to navigate the complexities of sales planning with relative ease.
Building a technology for mass organisation of distance learning for students in quarantine based on the Moodle platform
Authors: Spirin Oleg M. , Kolos Kateryna R. , Kovalchuk Olena A. , Demianchuk Olena O.
Published: January 2024

The COVID-19 pandemic has necessitated the rapid transition to distance learning for students worldwide. This paper examines the current state of distance learning implementation in secondary schools of the Zhytomyr region in Ukraine. A survey of 2445 teachers found that most were using various software tools for distance learning without a unified learning management system. Analysis of the Moodle, Google Classroom, and "My Class" platforms showed Moodle to have significant advantages for supporting distance learning. To enable schools to leverage Moodle, an "Educational Portal for Secondary School" was developed at Zhytomyr Polytechnic State University using the Moodle platform. Based on this Moodle portal, the paper proposes a technology for the mass organisation of distance learning during quarantine. The technology combines the tools, electronic resources, course structure, and tutor competencies required for effective distance learning implementation.
Pembuatan beras analog dari Pati Garut dengan penambahan bahan fungsional
Authors: Habib Muhammad , Kusumayanti Heny
Published: January 2024

Tujuan dari penelitian ini adalah untuk mengetahui sifat fisiologis dan sensorik beras dengan sifat antioksidan dari pati garut, tepung mocaf dan puree rumput laut Gracilaria sp. Penelitian ini menggunakan rancangan acak kelompok (RAK) dua faktor. Faktor pertama adalah perbandingan pati garut: tepung mocaf, tiga level (25:75, 50:50, 75:25%). Faktor kedua adalah konsentrasi puree rumput laut Gracilaria sp yang mempunyai empat level yaitu ; 1; 2; dan 3%. Sesuai hasil penelitian didapatkan kadar air dan abu tertinggi pada perlakuan proporsi pati garut: tepung mocaf  25:75 dengan persentase rumput laut 3%, yaitu sebesar 2,15%. Kadar abu tertinggi pada perlakuan proporsi pati garut: tepung mocaf 25:75 dengan persentase rumput laut 3%, yaitu sebesar 1,18%. Kadar lemak tertinggi pada perlakuan proporsi pati garut: tepung mocaf 50:50 dengan persentase rumput laut 3% yaitu sebesar 2,91%. Kadar protein tertinggi pada perlakuan proporsi pati garut: tepung mocaf 25:75 dengan persentase rumput laut 2% yaitu sebesar 0,67%. Kadar karbohidrat tertinggi pada perlakuan proporsi pati garut: tepung mocaf 25:75 dengan persentase rumput laut 2% yaitu sebesar 97,20%. Total kalori tertinggi pada perlakuan proporsi pati garut: tepung mocaf 50:50 dengan persentase rumput laut 3% yaitu sebesar 410,87%.
Investigating the Effects of Dynamic Assessment on Chinese Undergraduates’ English Writing Performance in the Blended Learning Context
Authors: Xiao Yawei
Published: January 2024

Whereas the effectiveness of dynamic assessment has been investigated in multiple contexts, it has been under-investigated in the context of blended learning mode for writing performance. To address this gap, this study aims to explore the effects of dynamic assessment on Chinese undergraduates’ writing performance as overall writing performance and writing complexity, accuracy and fluency in the blended learning context. To this end, a quasi-experiment was carried out with two intact classes from a Chinese university, one being the control group (n=34) and the other experimental group (n=36). A 12-week intervention was conducted in English writing classes under the blended learning mode, with the experimental group receiving dynamic assessment while the control group having traditional static assessment. At the end of the experiment, six students attended a semi-structured interview. The findings revealed that the experimental group improved significantly in writing performance in terms of overall scores, lexical density, lexical sophistication, and accuracy. However, dynamic assessment had no significant effect on lexical diversity, syntactic complexity and fluency. Besides, the interview findings evidenced that the students held positive attitudes toward the use of dynamic assessment in English writing classes in the blending learning context. Implications for writing instruction and future research are discussed.
The Challenges of Creating a Bilingual (English-Italian) E-Dictionary of Sports and Games Terminology
Authors: Franceschi Daniele
Published: January 2024

The aim of this paper is twofold. It firstly intends to provide an overview of the existing bilingual English-Italian dictionaries of sports and games terminology, in order to illustrate their main features and consider how this area of ESP (English for Special Purposes) lexicography may be improved. In the second part, a hypothetical e-dictionary entry is presented, taking as an example the lemma padel, indicating a new discipline that has become very popular in the past few years. The advantages of using online multimodal and multimedial dictionaries are discussed, while also making reference to the challenges of creating them: on the one hand, they make it possible to incorporate a plethora of information also via external hyperlinks, which makes them more dynamic resources with an encyclopedic character, but on the other hand it is necessary to constantly update dictionaries as hyperlinks ‘age’ over time and new disciplines appear. The inclusion of authentic material may also be problematic due to copyright reasons.
The Development of ESP Lexicon Through New Combining Forms
Authors: Mattiello Elisa
Published: January 2024

This paper investigates the role of new combining forms in the formation of neologisms which are currently expanding the lexicon of English for Special Purposes (ESP). In the past, only neoclassical combining forms, such as initial bio- or final -logy (in biology), were productively used in ESP. Nowadays, specialized combining forms also include abbreviated forms of existing words (e.g., cyber- from cybernetic in cyber-attack), as well as secreted (i.e. reinterpreted) forms (e.g., -bot from robot denoting ‘a type of automated program or software’ in knowbot). The paper explores a set of combining forms attested since the second half of last century in the online version of the Oxford English Dictionary (OED) with the aim to demonstrate how specialized sectors, such as science or information technology, are being enriched by series of combining-form combinations. The paper conducts quantitative analyses in the Corpus of Contemporary American English (COCA) and the News on the Web Corpus (NOW) to substantiate the frequency and stability of specialized combining forms and their profitability in the formation of both novel and nonce words.