bluuebunny/crossref_metadata_2025 huggingface dataset:
Escolas em foco: uso de dados por gestores escolares
Authors: Núñez Carolina Portela
Published: May 2021

Em 2015, a Secretaria Municipal de Educação do Rio de Janeiro (SME-RJ) implementou um programa com base no incentivo ao uso de dados por gestores escolares, chamado Escolas em Foco. O artigo apresenta resultados de uma análise de entrevistas realizadas com gestores de nove escolas municipais participantes do programa, que esteve em vigor em 400 escolas da rede de 2015 a 2016. O objetivo do estudo foi investigar percepções de gestores sobre apropriações e uso de dados educacionais para planejamento pedagógico. Os resultados mostram que o programa teve boa recepção pela maioria dos gestores entrevistados, mesmo estes não tendo compreendido bem o seu funcionamento, e que os gestores demandam mais por ajuda material e de pessoal do que de formação por parte das políticas educacionais.
Apresentação do Dossiê "Gestão democrática"
Authors: Do Amaral Daniela Patti , De Oliveira Ana Cristina Prado
Published: May 2021

Apresentação do Dossiê Gestão democrática
CÍRCULOS RESTAURATIVOS: UMA EXPERIÊNCIA DE ENFRENTAMENTO À VIOLÊNCIA ESCOLAR
Authors: Leajanski Alison Diego , Pimentel Carla Silvia
Published: May 2021

A investigação, apresentada neste texto, revela a experiência de um colégio público do município de Ponta Grossa – PR com a utilização de Círculos. São práticas de Justiça Restaurativa, originárias de povos ancestrais, agora presentes em ambientes escolares. A pesquisa, que foi realizada com um grupo de facilitadores do colégio, tem abordagem qualitativa descritiva, de cunho interpretativo. Em síntese, os resultados demonstraram que os Círculos estabeleceram o diálogo como meio de resolução de conflitos, permitindo a prevenção e enfrentamento à violência escolar para construção de ambientes de paz. Ainda revelaram, que brigas dentro e fora do colégio diminuíram, bem como as depredações, mas, em especial, que os alunos desenvolveram sentimento de pertença ao colégio.
Trajetórias formativas e profissionais de pedagogia frente à inclusão educacional
Authors: Schmengler Angélica Regina , Silva Mariane Carloto da , Pavão Sílvia Maria de Oliveira
Published: May 2021

Essa escrita busca refletir sobre o processo formativo inicial em Pedagogia acerca da atuação frente aos estudantes público-alvo da Educação Especial. A pesquisa definiu-se como qualitativa, do tipo exploratória, sendo utilizados questionários com cinco pedagogas de uma escola municipal de Santa Maria/RS. As profissionais tiveram contato com uma ou mais disciplinas da Educação Especial, mas os conhecimentos não foram suficientes. Evidenciaram aspectos que dificultam a prática inclusiva: salas de aulas lotadas; falta de sistema educacional preparado para a inclusão; diferentes especificidades que nem sempre são abordadas nas disciplinas; distância entre teoria e prática/realidade das escolas. É preciso repensar os cursos que formam Pedagogos(as) para a atuação frente à inclusão educacional.
Avaliação da leitura de crianças em processo de alfabetização
Authors: Silva Olívia Coelho da , Ribeiro Ana Paula De Medeiros
Published: May 2021

O artigo apresenta uma investigação documental com o objetivo de identificar e analisar os instrumentos de avaliação em leitura propostos pela Secretaria Municipal de Fortaleza e pela escola aplicados aos alunos do 2º ano. Anualmente, as crianças são avaliadas pelo Sistema Permanente de Avaliação da Educação Básica do Ceará. Essa avaliação externa influencia consideravelmente as ações pedagógicas da escola.  As conclusões são: o instrumental de avaliação disponibilizado pela Secretaria Municipal de Educação apresenta fragilidades quanto ao adequado diagnóstico sobre a compreensão leitora dos alunos; observou-se que o teste denominado simulado analisado foram identificados alguns deslizes técnicos na elaboração dos comandos e nas alternativas de respostas em itens que compuseram o teste.
O ensino de genética para cegos numa perspectiva inclusiva
Authors: Silva Maria Luciane Cardoso , Silva Cleber Silva
Published: May 2021

Trata-se de pesquisa ação que apresenta e discute os resultados de aplicação de um produto educacional que considerou um contexto real de ensino-aprendizagem de uma discente cega nas aulas de biologia. Através de observação participante e questionários semiestruturados, identificamos a necessidade da elaboração de um produto educacional para o ensino de genética que atendesse as necessidades de aprendizagem da estudante cega, mas que também se configurasse como recurso alternativo de aprendizagem para estudantes normovisuais. Concluímos que a utilização da tecnologia educacional pelos discentes foi um momento agregador nas relações estabelecidas uma vez que o produto multissensorial proposto se mostrou como um recurso que fortaleceu o processo de ensino-aprendizagem.
KECEPATAN GELOMBANG GESER (VS) DAN KETEBALAN SEDIMEN (H) DI KABUPATEN KLATEN DARI DATA MIKROTREMOR
Authors:   Universitas Islam Indonesia, Arifudin Anggit
Published: June 2021

Research on Shear Wave Velocity (vs) and Sediment Thickness (h) in Klaten Regency, Central Java from field microtremor data aims to determine the thickness of sediment or soft sediment as one factor of high and low earthquake vulnerability. Microtremor data was collected using a three-component TDS 303 seismometer covering 111 measuring points in the Klaten Regency area. In this study, the sediment thickness was calculated using the equation shear wave velocity (vs) divided by four times the dominant frequency (fg). The dominant frequency (fg) value is obtained from the HVSR curve. In contrast, the shear wave velocity value (vs) used in this study is the inversion value of the HVSR curve, which is modeled based on borlog data at the Wedi Church, equated for all measurement points. The map of the shear wave velocity distribution at each microtremor measuring point has a vs value; this value is used to calculate the thickness of the sediment at each end. So that the distribution of the thickness value of the sediment at each point is obtained, then a thickness map is made covering the study area. The results showed that, in general, the research area has a Vs value in the effects of the HVSR curve inversion ranging from 130 m/s to 570.83 m/s, Vs average 275.68 m/s. The areas with vs are relatively high in the southern part of Gantiwarno, Wedi, and Bayat subdistricts directly adjacent to Gunung Kidul. Areas with relatively low-value of vs are in Prambanan Subdistrict, Northern Wedi Subdistrict, Trucuk Subdistrict, Jogonalan Subdistrict, South Klaten District, Central Klaten District, and Kalikotes Subdistrict. For sediment thickness (h) ranges from 5.105 m to 113.648 m. Areas with relatively high sediment thickness are located in parts of Wedi Subdistrict with a thickness of up to 110 m. Areas with medium thickness (around 60 to 90 m) are in the Gantiwarno sub-district, Prambanan district, and the southern part of the Jogonalan sub-district. In Bayat District, it has a low thickness (about 5 to 30 m) located in the proves and mountains of the Paseban area and the tomb of Sunan Pandanaran. The result shows that areas with high sediment thickness, namely in Wedi District, have a high level of earthquake vulnerability.
Social Media Data Misuse
Authors: Soussan Tariq , Trovati Marcello
Published: May 2021

The present high-tech landscape has allowed institutes to undergo digital transformation in addition to the storing of exceptional bulks of information from several resources, such as mobile phones, debit cards, GPS, transactions, online logs, and e-records. With the growth of technology, big data has grown to be a huge resource for several corporations that helped in encouraging enhanced strategies and innovative enterprise prospects. This advancement has also offered the expansion of linkable data resources. One of the famous data sources is social media platforms. Ideas and different types of content are being posted by thousands of people via social networking sites. These sites have provided a modern method for operating companies efficiently. However, some studies showed that social media platforms can be a source for misinformation at which some users tend to misuse social media data. In this work, the ethical concerns and conduct in online communities has been reviewed in order to see how social media data from different platforms has been misused, and to highlight some of the ways to avoid the misuse of social media data.
On the Riemann Hypothesis for the Zeta Function
Authors: Yang Xiao-Jun
Published: June 2021

In this paper we address some variants for the products of Hadamard and Patterson. We prove that all zeros of the Riemann $\Xi$--function are real. We also prove that the Riemann hypothesis is true. The equivalence theorems associated with the Riemann zeta--function are obtained in detail.
Elexacaftor–Tezacaftor–Ivacaftor Therapy for Cystic Fibrosis Patients with the F508del/Unknown Genotype
Authors: Comegna Marika , Terlizzi Vito , Salvatore Donatello , Colangelo Carmela , Di Lullo Antonella Miriam , Zollo Immacolata , Giovanni Taccetti , Castaldo Giuseppe , Amato Felice
Published: June 2021

The new CFTR modulator combination, elexacaftor/tezacaftor/ivacaftor (Trikafta) was approved by the FDA in October 2019 for treatment of Cystic Fibrosis in patients 12 years of age or older who have at least one F508del mutation in one allele and a minimal-function or another F508del mutation in the other allele. However, there is a group of patients, in addition to those with rare mutations, in which despite the presence of a F508del in one allele, it was not possible to identify any mutation in the other allele. Today these patients are excluded from treatment with Trikafta. In Italy CF patients carrying F508del/unknown represent about 3% (156 patients) of the overall Italian CF patients. In this paper we show that the Trikafta treatment of nasal epithelial cells, derived from F508del/Unknown patients, results in a significant rescue of CFTR activity. Based on our findings, we think that the F508del/Unknown patients considered in this study could obtain clinical benefits from Trikafta treatment, and we strongly suggest their eligibility for this type of treatment.This study, adding further evidence in the literature, once again confirms the validity of functional studies on nasal cells in the cystic fibrosis theratyping and personalized medicine.
Integrated Environmental Design and Robotics Workflow for Double-Skin Facade Perforation Onsite
Authors: Khairadeen Ali Ahmed , Lee One Jae
Published: June 2021

In contemporary design practices, there is a disconnect between the design techniques used for early-stage design experimentation and performance analysis, and those used for the manufacture and construction. This study addresses the problems in developing an integrated digital design workflow and provides a research framework for integrating environmental performance requirements with robotic manufacturing processes on a construction site. The proposed method enables the user to import a design surface, identify design parameters, set several environmental performance goals, and thereafter simulate and select a robotic building strategy. Based on these inputs, design alternatives are developed and evaluated, considering their robotically simulated constructibility, in terms of their performance criteria. To validate the proposed method, the design is evaluated in an experiment wherein a double-skin facade perforation is generated using the proposed methodology. The results suggest a heuristic feature to improve the simulated robotic constructibility. Moreover, the functionality of the prototype is demonstrated.
Leishmania in 360: Guidelines for Exosomal Research
Authors: Gabriel Áurea M. , Galué-Parra Adan , Pereira Washington Luiz A. , Pedersen Ketil W. , Silva Edilene O.
Published: June 2021

Leishmania parasites are a group of kinetoplastid pathogens that cause a variety of clinical forms while maintaining cell communication by secreting extracellular vesicles. Emerging technologies have been adapted for the studies of Leishmania-host-cell interactions to enable broad scale analysis of parasite extracellular vesicles. Leishmania extracellular vesicles (LEVS) are naturally released spheroidal nanoparticles of polydispersed suspensions surrounded by a lipid layer of membrane. Although LEVs have increasingly gained in importance, much is still unexplained, including bioavailability and function in the complex molecular mechanisms of pathogenesis. Considering the importance of LEVs in the parasite-host interaction and in the parasite-parasite relationships emerged during evolution, the current review aims at giving an overview of Leishmania summarizing knowledge and formulating guidelines for LEVs research. In the end, we report, direct methods for specific isolation of LEVs from promastigotes and amastigotes culture supernatant suitable for a range of different downstream applications increasing the compatibility and reproducibility to establish optimal and comparable isolation conditions and full LEVs characterization, and crucial immunomodulatory events triggered by this important group of parasites.
Measurement of Ankle Joint Movements using IMUs during Running
Authors: Kim Byonghun , Hong Sunghyun , Oh Inwook , Lee Yangwoo , Kee Inho , Lee Saeyong
Published: June 2021

Gait analysis has historically been implemented in laboratory settings with expensive instruments; however, recently, wearable sensors have allowed the integration into clinical applications and use in daily activities. Previous studies have shown poor validity of ankle joints using inertial measurement units (IMUs), especially for small movement ranges. The purpose of this study was to validate the ability of commercially available IMUs to accurately measure the ankle joint angles during running. Ten healthy subjects participated in the study. Validation was performed by comparing the ankle joint angles measured using the wearable device with those obtained using the gold standard motion capture system during running. Reliability was evaluated using the intraclass correlation coefficient and standard error of measurement, whereas validity was evaluated using Pearson coefficient correlation method. Day-to-day reliability was excellent in the two planes for ankle joints. Validity was good in both sagittal and frontal planes for ankle joints. The results suggested that the developed device might be used as an alternative tool to the 3D motion capture system.
Immune-related Endocrine Dysfunctions in Combined Modalities of Treatment: Real-world Data
Authors: Chan Wing Lok , Choi Horace Cheuk-Wai , Ho Patty Pui-Ying , Lau Johnny Kin-San , Tse Rosa Pui-Ying , Au Joyce , Lam Vivian , Liu Ronald , Ho Isaac , Wong Charlotte , Cheung Ben , Lam Eric , Chow Daryn , Lam Ka-On , Yuen Kwok-Keung , Kwong Dora Lai-Wan
Published: June 2021

Abstract Background The number of immune-related endocrine dysfunctions (irEDs) has concurrently increased with the widespread use of immunotherapy in clinical practice and further expansion of the approved indications for immune checkpoint inhibitor (ICI) combinations using different modalities of anti-cancer treatment. Method A retrospective analysis was conducted on consecutive patients >18 years of age with advanced solid malignancies who had received at least one dose of anti-programmed cell death protein 1 (anti-PD-1) and/or anti-CTLA4 antibodies between January 2014 and December 2019 at a Hong Kong university hospital. Patients were reviewed for up to two months after the last administration of an ICI. The types, onset times and grades of irEDs, including hypothyroidism, hyperthyroidism, adrenal insufficiency and immune-related diabetes mellitus, were recorded. Factors associated with irEDs were identified using multivariate analysis. Result A total of 953 patients (male: 603, 64.0%; median age: 62.0 years) received ICIs during the study period. Of these, 580 patients (60.9%) used ICI-alone, 132 (13.9%) used dual-ICI, 187 (19.6%) used an ICI combined with chemotherapy (chemo+ICI), and 54 (5.70%) used immunotherapy with a targeted agent (targeted+ICI). A significantly higher proportion of patients using targeted+ICI had irEDs and hypothyroidism; in contrast, a higher proportion of patients using dual-ICI had adrenal insufficiency. There was no significant difference in the incidence of irED between the younger (<65 years) and older (>65 years) patients. Using logistic regression, only treatment type was significantly associated with irEDs. Notably, older patients had a higher risk of having immune-related diabetes mellitus. Conclusions This large, real-world cohort demonstrates that combining ICI with targeted therapy has a higher risk of overall irED and hypothyroidism. Immunotherapy is safe and well-tolerated regardless of age, but close monitoring of fasting glucose is needed in older populations.
Fermentation Dynamics of Ethiopian Traditional Beer (Tella) As Influenced by Substitution of Gesho (Rhamnus prinoides) With Moringa Stenopetala as Innovation for Nutrition
Authors: Birhanu Ajanw Maru , Teferra Tadesse Fikre , lema Tesfu Bekele
Published: June 2021

This study was designed to improve Ethiopian traditional beer – tella with the substitution of gesho by moringa leaves to enhance micronutrients. Substation of gesho by moringa from 50 – 100% against the biochemical dynamics, nutritional and sensorial profiles of tella was assessed. Incorporation of moringa suppressed the activities of yeast and favored that of lactic acid bacteria, which shifted the property of the product from mild alcoholic nature to low alcoholic and mild acidic nature, revealing the probiotic potential of tella. Moringa leaves at 100% substitution for gesho resulted in to the least yeast count compared to the other formulations. The storage of tella samples over periods of 10 days also strengthened the probiotic nature of tella by drastically reducing the yeast cell counts (from 5 logs to <1). This corresponded to the slow increase in the acidity (0.63 to 0.99%), indicating comparatively higher activities of lactic acid bacteria. The best nutritional contents (dietary minerals) and sensorial acceptance of the product was attained at the 50% substitution of gesho by moringa. The implication of the present study is that ethnic foods and beverages can be innovated to meet the nutritional needs of the community
A Learning Interaction Bbetween Statistical Learning Experiments
Authors: Richtsmeier Peter , Goffman Lisa
Published: June 2021

When participants in a statistical learning paradigm are asked to learn from two incompatible or competing inputs, they often fail to learn from one or both inputs. This study presents the results of two experiments that were both completed by one group of typically developing four-year-old children. One experiment targeted word-medial consonant patterns (phonotactics), whereas the other targeted strong-weak and weak-strong stress patterns (prosody). The order of the experiments was critical for learning outcomes in the phonotactics experiment: When children learned phonotactics first, their production accuracy increased following exposure to a high frequency input. When children learned phonotactics second, however, their production accuracy dropped when they were exposed to the high frequency input. Results from the prosody experiment were inconclusive, with limited evidence of any learning effect. Overall, the results suggest that children may conflate learning experiences, and patterns learned from an initial experimental input compete with patterns in a subsequent experiment. When considering natural language acquisition, the results suggest that an isolated episode of learning may lead to generalizations that are incompatible with later input, and possibly, with larger patterns in the language.
Energy-Efficient Adaptive Sensing Scheduling in Wireless Sensor Networks using Fibonacci Tree Optimization Algorithm
Authors: Wu Liangshun , Cai Hengjin
Published: June 2021

Wireless sensor networks are attractive largely because they need no wired infrastructure. But precisely this feature makes them energy constrained. Recent studies find that sensing behaviors that are otherwise deemed efficient consume comparable energy with communication. The duty cycle scheduling is perceived as contributing to achieving energy efficiency of sensing. Because of different research assumptions and objectives, various scheduling schemes have various emphases. This paper designed an adaptive sensing scheduling strategy. The objective function of the scheduling strategy includes minimizing average energy expenditure and maximizing sensing coverage (reducing event miss-rate), and it requires relatively loose assumptions. We determine the functional relationship between the variables of the objective function and the step-size parameters of the proposed strategy through the numerical fitting. We found that the objective function aggregated by the fitting functions is a bivariate multi-peak function that favors the Fibonacci tree optimization algorithm. Once the optimization of parameters is done, the strategy can be easily deployed and behaves consistently in the coming hours. We name the proposed strategy as “FTOS”. The experimental results show that the Fibonacci tree optimization algorithm gets a better optimistic effect than the comprehensive learning particle swarm optimization (CLPSO) algorithm and differential evolution (DE) algorithm. The FTOS strategy is superior to the fixed time scheduling strategy in achieving the scheduling objectives. It also outperforms other strategies with the same scheduling objectives such as LDAS, BS, DSS and PECAS.
Metric Number in Dimension
Authors: Garrett Henry
Published: June 2021

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Eﬀects of Cornell-type Potential on Klein-Gordon Oscillator Under a Linear Central Potential Induced by Lorentz Symmetry Violation
Authors: Ahmed Faizuddin
Published: June 2021

In this work, we study a Klein-Gordon oscillator subject to Cornelltype potential in the background of the Lorentz symmetry violation determined by a tensor out of the Standard Model Extension. We introduce a Cornell-type potential S(r) = (η_L\,r + \frac{η_c}{r} ) by modifying the mass term via transformation $M → M + S(r)$ and then coupled oscillator with scalar particle by replacing the momentum operator $\vec{p}→ (\vec{p}+ i\,M\,ω\,\vec{r})$ in the relativistic wave equation. We see that the analytical solution to the Klein-Gordon oscillator equation can be achieved, and a quantum eﬀect characterized by the dependence of the angular frequency of the oscillator on the quantum numbers of the relativistic system is observed
Гибридный алгоритм для задач автоматизированной адаптации гидродинамических моделей с использованием трассерных исследований
Authors: Казаков Алексей Александрович , Kazakov Aleksei Aleksandrovich , Ломовицкий Павел Викторович , Lomovitskiy Pavel Viktorovich , Хлюпин Алексей Николаевич , Khlyupin Aleksey
Published: May 2021

Представлен гибридный алгоритм для решения совместных обратных задач, разработанный на основе стохастического алгоритма оптимизации sNES и техники построения Adjoint-градиента. Эффективность алгоритма проверена на задачах адаптации полей пористости и проницаемости по историческим данным разработки и
по результатам трассерных исследований. Численно моделируется распространение пассивной примеси и течение флюида в пласте. Использование предложенного
гибридного алгоритма позволило значительно снизить число вызовов симулятора
для достижения сопоставимого качества адаптации.
Developing a Landslide Susceptibility Map Using the Analytic Hierarchical Process in Ta Van and Hau Thao Communes, Sapa, Vietnam
Authors: Le Thi Thanh Thuy , Tran The Viet , Hoang Viet Hung , Bui Van Truong , Bui Thi Kien Trinh , Nguyen Ha Phuong ,   Department of Water Resources Engineering, Thuyloi University  175 Tay Son Street, Dong Da District, Hanoi, Vietnam,   Department of Civil Engineering, Thuyloi University, Hanoi, Vietnam,   Institute of Civil Engineering, Thuyloi University, Hanoi, Vietnam
Published: May 2021

Landslides are considered one of the most serious problems in the mountainous regions of the northern part of Vietnam due to the special topographic and geological conditions associated with the occurrence of tropical storms, steep slopes on hillsides, and human activities. This study initially identified areas susceptible to landslides in Ta Van Commune, Sapa District, Lao Cai Region using Analytical Hierarchy Analysis. Ten triggering and conditioning parameters were analyzed: elevation, slope, aspect, lithology, valley depth, relief amplitude, distance to roads, distance to faults, land use, and precipitation. The consistency index (CI) was 0.0995, indicating that no inconsistency in the decision-making process was detected during computation. The consistency ratio (CR) was computed for all factors and their classes were less than 0.1. The landslide susceptibility index (LSI) was computed and reclassified into five categories: very low, low, moderate, high, and very high. Approximately 9.9% of the whole area would be prone to landslide occurrence when the LSI value indicated at very high and high landslide susceptibility. The area under curve (AUC) of 0.75 illustrated that the used model provided good results for landslide susceptibility mapping in the study area. The results revealed that the predicted susceptibility levels were in good agreement with past landslides. The output also illustrated a gradual decrease in the density of landslide from the very high to the very low susceptible regions, which showed a considerable separation in the density values. Among the five classes, the highest landslide density of 0.01274 belonged to the very high susceptibility zone, followed by 0.00272 for the high susceptibility zone. The landslide susceptibility map presented in this paper would help local authorities adequately plan their landslide management process, especially in the very high and high susceptible zones.
Care and Management of Voice Change in Thyroid Surgery: Korean Society of Laryngology, Phoniatrics and Logopedics Clinical Practice Guideline
Authors:   Korean Society of Laryngology, Phoniatrics and Logopedics Guideline Task Force, Ryu Chang Hwan , Lee Seung Jin , Cho Jae-Gu , Choi Ik Joon , Choi Yoon Seok , Hong Yong Tae , Jung Soo Yeon , Kim Ji Won , Lee Doh Young , Lee Dong Kun , Lee GIljoon , Lee Sang Joon , Lee Young Chan , Lee Yong Sang , Nam Inn Chul , Park Ki Nam , Park Young Min , Sung Eui-Suk , Son Hee Young , Seo In Hyo , Lee Byung-Joo , Lim Jae-Yol
Published: June 2021

Voice change is a common complaint after thyroid surgery and has a significant impact on quality of life. The Korean Society of Laryngology, Phoniatrics and Logopedics assembled a task force to establish guideline recommendations on education, care, and management related to thyroid surgery. The guideline recommendations encompass preoperative voice education, management of anticipated voice change during surgery, and comprehensive voice care after thyroid surgery, and include in-depth information and up-to-date knowledge based on validated literature. The committee constructed 14 key questions (KQs) in three categories—preoperative (KQ 1–2), intraoperative (KQ 3–8), and postoperative (KQ 9–14) management—and developed 18 evidence-based recommendations. The Delphi survey reached an agreement on each recommendation. A detailed evidence profile is presented for each recommendation. The level of evidence for each recommendation was classified as high-quality, moderate-quality, or low-quality. The strength of each recommendation was designated as strong or weak considering the level of evidence supporting the recommendation. The guidelines are primarily targeted toward physicians who treat thyroid surgery patients and speech-language pathologists participating in patient care. These guidelines will also help primary care physicians, nurses, healthcare policymakers, and patients improve their understanding of voice changes and voice care after thyroid surgery.
Employing NADH Dehydrogenase Subunit 1 in the Determination of Echinococcus granulosus Strain in Sheep, Cattle and Human in Thi-Qar Province, Iraq
Authors: AL-Asadi Sarmad Awad Mozan , Hansh Wesam Jasim , Awad Abdul-Hussien Habash
Published: June 2021

Echinococcosis is a zoonotic disease caused by the larval stage of the tapeworm Echinococcus granulosus. This disease is an important public health and a significant economic issue in Iraq, where the lungs and livers are the popular places of infection. The aim of the current study focused on using the molecular techniques in the detection of an E. granulosus strain that causes cystic echinococcosis to human, sheep and cattle in Thi-Qar province, Iraq. In the current study, thirty isolates of E. granulosus were collected from 10 human hydatid cysts through surgery done at Al-Hussein Imam Teaching Hospital in Thi-Qar province and 10 sheep with 10 cattle hydatid cysts were obtained from the slaughterhouse in Thi-Qar province, Southern of Iraq to identify strains of E. granulosus which infect human and other intermediate hosts  (sheep and cattle). The molecular study was carried out on the isolates and a specific primer set for the mitochondrial dehydrogenase NADH subunit 1 (NAD1) gene was used. This primer set was amplified 400 bp of the NAD1 gene in all selected isolates. The PCR products for the twelve selected isolates of E. granulosus (4 isolates per intermediate host) were sequenced and the results for these twelve isolates showed that all sequenced isolates, except one isolate Eg_5, belonged to the sheep strain G1 and a slight genetic diversity was observed with the reference sequences of the strain G1. The exception was in the isolate Eg_5 isolated from a cattle liver, which was similar to the buffalo strain G3. This study concludes that the common E. granulosus strain in Thi-Qar province is G1.
APPLICATION OF INQUIRY BASED LEARNING MODEL USING STEM APPROACH TO REDUCE STUDENTS' INTRINSIC COGNITIVE LOAD
Authors: Sundari Rita , Ahmed Omnia Salah , Abdurrahman Abdurrahman , Herlina Kartini
Published: June 2021

This study is an experimental research using a quasi-experimental design with the type of non-equivalent control group pretest-posttest. This research aims to reduce Intrinsic Cognitive Load (ICL) through Inquiry Based Learning (IBL) model based STEM approach. This research was conducted at SMA Negeri 1 Seputih Banyak with the research subjects of class X IPA 1 students and X IPA 4. An data Intrinsic Cognitive Load obtained from essay the pretest-posttest (Task Complexity worksheet). Cognitive load test data analysis was performed using the data normality test, N-gain test and hypothesis test using the Paired Sample T-Test. The experimental class implements the Inquiry Based Learning model based audio and visual using STEM approach while the control class is nonaudio and visual. The results showed by the average value of N-Gain Intrinsic Cognitive Load (ICL) in the experimental class was 0.63 with the moderate category and the control class was 0.18 with the low category. Based on data analysis, can be concluded that there is a positive influence in the form of a decrease in the cognitive load Intrinsic Cognitive Load (ICL) in the experimental class using the Inquiry Based Learning model plus an audio and visual based  STEM approach.
DEVELOPING ELECTRONIC STUDENT WORKSHEET (E-WORKSHEET) BASED PROJECT USING FLIPHTML5 TO STIMULATE SCIENCE PROCESS SKILLS DURING THE COVID-19 PANDEMIC
Authors: Febriansyah Ferdi , Herlina Kartini , Nyeneng I Dewa Putu , Abdurrahman Abdurrahman
Published: June 2021

This research aims to develop worthy (in terms of validity and practicality) Electronic Student Worksheets (E-Worksheet) based project using FlipHTML5 in light interference topic. E-Worksheet developed to stimulate student’s science process skills. This research used design and development research (DDR) which consisted of 4 stages, namely analysis, design, development, and evaluation. The results of the product validity were assessed by experts consisting of two high school physics teachers and a lecturer from the physics education department of the University of Lampung who got an average score of 3.56 with the very valid category. The E-Worksheet practicality in terms of the legibility, the student views that was completed by 9 students, and the teacher views that was completed by 5 high school physics teachers got an average percentage of 90% with the very practical category. These results showed that E-Worksheet were valid and very practical to stimulate student’s science process skills. Based on teacher views, the E-Worksheet is very possible to be implemented in online and face-to-face learning especially in the covid-19 pandemic era. The E-Worksheet can be used as multimedia to support online learning.
GLOBAL TRENDS IN EDUCATIONAL POLICY IMPLEMENTATION AND THE COMPLEXITY OF QUALITY IN EDUCATION: A CAMEROONIAN PERSPECTIVE
Authors: Demboh Primus , Susanti Diah
Published: June 2021

This article argues that effective policy implementation strategies based on the concepts of equity, flexibility, accountability, creativity and innovation can raise students’ learning and bring about a significant economic and social development. Cameroon is an example of an education system that has over the years developed very important policies in the hope of raising the quality of knowledge that students learn in schools. The country’s education sector strategy for 2020/2030 has a good number of policies which are aimed at developing skills and promoting the spirit of entrepreneurship in the learners from the primary through the secondary to higher levels. However, most of these policies have either failed or have taken a far longer time to attain their set objectives. Cameroon like many other countries in Africa, Asia, and the rest of the world seem to present a mismatch between their educational policy objectives and what is implemented in the field. This situation is very much unlike the case in many other countries where effective educational reforms have brought about measurable growth in their economies. As a result of the numerous and diverse challenges involved in this process, very few systems attain a significant level of success in these policies. Thus, they fail because of their inability to handle the various challenges that come with the struggle for quality in education reform. This study focuses on some of those challenges that are likely to be faced by any educational system, in their struggle to achieve quality in their education; why these challenges arise and how some systems have overcome them to attain their objectives. Based on the case study of Cameroon, the study comes up with a number of factors of failures in most systems. It is built on the idea that challenges are always part of the process of education, and success can only be achieved by braving them
A ranking-based differential evolution algorithm for hybrid flow shop sustainable scheduling
Authors: Wang Liming , Kong Lin , Li Fangyi , Lv Xiaoteng
Published: June 2021

With the increasing of environmental pressure, the sustainable production for hybrid flow shops (HFS) has attracted more attention due to its broad industrial applications. In implementing the sustainable production of HFS, the selection of parallel machines for various jobs is a vital step. In light of this, a multi-objective mathematical model for minimization of makespan and energy consumption of HFSP was formulated. The sustainability of parallel machines were evaluated and ranked according to fuzzy TOPSIS method. To solve the multi-objective model of HFSP, an improved differential evolution algorithm was presented to assign the job with the ranked parallel machines, which can narrow the search scope and accelerate the convergence speed. Finally, a case study was presented to evaluate the effectiveness of the proposed ranking-based algorithm and to prove the feasibility of the model. The results showed that the proposed improved algorithm outperforms NSGA-II and PSO in searching for non-dominated solutions, which can effectively solve the sustainable production of HFSP.
Observation and Analysis of Solar Flares that Cause Large-area Short-wave Communication Interruption
Authors: Kangpo Zhou , youtian Niu , weina Liu , zhaodi Wang , songhao Guo , bei Li , xiukun Zhao , zhe Wang
Published: June 2021

When a solar flare erupts, the sun emits a flood of X-rays and high-energy particles that reach Earth at the speed of light, causing a sudden ionospheric disturbance event (SID event). The D layer of the ionosphere absorbs high-frequency radio signals. With the increase of flare intensity, the D layer's absorption capacity becomes stronger, which leads to the decline of shortwave communication quality and even the interruption of shortwave communication. In this paper, solar flares, which caused large area short-wave communication interruption in recent years, are observed and analyzed by very low frequency (VLF) method, and the influence of solar flares on short-wave communication is summarized. Finally, several methods to deal with the short-wave communication interruption caused by solar flares are proposed.
Convection-Permitting Regional Climate Simulations Over Tibetan Plateau: Re-Initialization Versus Spectral Nudging
Authors: Ma Mengnan , Hui Pinhong , Liu Dongqing , Zhou Peifeng , Tang Jianping
Published: June 2021

Two regional climate simulation experiments (spectral nudging and re-initialization) at convection-permitting scale are conducted using the WRF model over the Tibetan Plateau (TP). The surface air temperature (T2m) and the precipitation in summer during 2016–2018 are evaluated against the in-situ station observations and the Global Satellite Mapping of Precipitation (GSMaP) dataset. The results show that both experiments can successfully capture the spatial distribution and the daily variation of T2m and precipitation, with reasonable cold bias for temperature, dry bias for precipitation when compared with the station observations. In addition, the diurnal cycle of precipitation is investigated, indicating that both experiments tend to simulate the afternoon precipitation in advance and postpone the night precipitation. The precipitation bias is reduced by using the spectral nudging technique, especially at night and early morning. Possible causes for the differences between the two experiments are also analyzed. The daytime surface net radiation contributes a lot to the cold biases in the re-initialization experiment, and the stronger low-level moisture flux convergence leads to the wet biases. These results can provide valuable guidance for further fine-scale simulation studies over the TP.
Prenatal Octamethylcyclotetrasiloxane Exposure Impaired Proliferation of Neuronal Progenitor, Leading to Motor, Cognition, Social and Behavioral Functions
Authors: Tran Dinh Nam , Park Seon-Mi , Jung Eui-Man , Jeung Eui-Bae
Published: June 2021

Cyclic siloxane octamethylcyclotetrasiloxane (D4) is an endocrine-disrupting chemical (EDC) used widely in detergent products, cosmetics, and personal care products. Recently, robust toxicological data for D4 has been reported, but the adverse effects of D4 on brain development are unknown. Here, pregnant mice on a gestational day 9.5 were treated daily with D4 to postnatal day 28, and the offspring mice were studied. The prenatal D4-treated mice exhibited cognitive dysfunction, limited memory, and motor learning defect. Moreover, prenatal D4 exposure reduced the proliferation of neuronal progenitors in the offspring mouse brain. Next, the mechanism(s) through which D4 regulated the cell cycle was investigated. Aberrant gene expression, such as cyclin-dependent kinases CDK6 and cyclin-dependent kinase inhibitor p27, was found in the prenatal D4-treated mice. Furthermore, estrogen receptor ERa and ERb increased in the brain of prenatal D4-treated mice. Overall, these findings suggest that D4 exerts estrogen activity that affects the cell cycle progression of neuronal progenitor cells during neurodevelopment, which may be associated with cognitive deficits in offspring.
Using an Online Nominal Group Technique to Determine Key Implementation Factors for COVID-19 Vaccination Programmes in Community Pharmacies
Authors: Michel Dorothee Elsbeth , Iqbal Ayesha , Faehrmann Laura , Tadić Ivana , Paulino Ema , Chen Timothy F , Moullin Joanna C
Published: June 2021

Background: One vital strategy to fight the COVID-19 pandemic is the rapid roll-out of vaccination programmes. In a number of countries pharmacists are joining the vaccination programme workforce, including plans to involve community pharmacies in the process. Objectives: (1) to determine key implementation factors for rapid roll-out of COVID-19 vaccination programmes in European community pharmacies and (2) to test an online approach of the nominal group technique (NGT) to generate ideas and reach consensus to achieve the first aim. Setting: In February 2021, during a workshop at the 12th Working Conference of the Pharmaceutical Care Network Europe (PCNE). Methods: An online nominal group technique workshop over 10 hours was conducted. Identified implementation factors were mapped to the Framework for the Implementation of Services in Pharmacy (FISpH) and assessed in terms of importance and changeability.Main outcome measure: Consensus of key implementation factors.Results: In total, 85 implementation factors were identified. The top 3 factors were the same for both criteria: (Regular) Staff training on correct vaccination procedure / to perform hands-on injection technique; Training in basic life support / first aid (Cardiopulmonary resuscitation), and; Definition of process, roles and responsibilities in the team. Conclusion: An online NGT process enabled international collaboration in gathering diverse perspectives on the implementation of COVID-19 vaccination programmes in a time and cost-efficient manner. The process was effective in identifying implementation factors and finding solutions. Online NGT processes may be suitable for other implementation problems, not only during a pandemic.
ENSURING NATIONAL SECURITY OF UKRAINE: OBJECTIVE LIMITATIONS AND TARGETS OF OPTIMIZATION
Authors: Kuzmenko O. , Boiko A. , Levchenko V.
Published: May 2021

The paper formalizes the system of restrictions and national security targets. The proportion of budgetary resources allocated for implementing the environmental tax reform was chosen as quantitative restrictions. The effective indicator is the level of national security. The time limit was established based on the study of the period of delay of the expected impact of changes in the system of administration, payment, and distribution of the environmental tax on national security. The formalization of quantitative restrictions and national security targets was carried out using structural modeling. This method was based on the following logic: the impact of the growth rate of the environmental tax on national security, the impact of the growth rate of the environmental tax on budget revenues, the impact of budget revenues on the national security of Ukraine.
In this case, the level of environmental taxes is chosen as an exogenous latent variable, described using an explicit exogenous variable – the increase in revenues from the environmental tax. The following endogenous latent variables were selected: a highly effective mechanism for ensuring national security and the share of budgetary resources aimed at implementing tax reform). Each endogenous latent variable is described using one endogenous explicit variable: the level of national security and, accordingly, revenues of the consolidated budget of Ukraine.
In turn, the definition of time constraints and national security targets occurs in the following sequence: 1) adaptation of the Foster-Stewart method for verifying the stationarity of the time series of mean values from binary values; 2) construction of non-linear multivariate regression and testing the hypothesis about the time constraint.
Based on practical calculations, it has been established that national security requires a radical transformation of the entire system of administration, distribution, and establishment of the level of the tax burden. At the same time, budget expenditures on tax reform should not exceed 18%. However, these reforms should be implemented in one year since it has been proven that a temporary limitation of the level of national security is the annual value of the reform of the environmental taxation system.
THE POLITICS OF A LOCAL SUFISM IN CONTEMPORARY INDONESIA
Authors: Ahmadi Rizqa
Published: May 2021

This article discusses the politics of local Sufi group (tarekat) in Indonesia, the Shiddiqiyyah. It addresses the locality of Shiddiqiyah tarekat and its politics during New Order Indonesia and following the fall of the regime. It is argued that the Shiddiqiyah, a local tarekat with its roots in East Java and later successfully welcomes national reputation, is an example of a tarekat that utilizes nationalistic slogan to expand its influence as well as to protect the tarekat from heretic accusation. Through a series of intensive fieldwork, the article argues that the Shiddiqiyyah has successfully maintained ideological patronage to the New Order Indonesia through nationalistic slogan which has been a core value of the group. The doctrine of nationalism has been translated in Sufi and Javanese idioms and become fundamental doctrine of the Shiddiqiyyah.
Anti-Holley detected in a primary immune response
Authors: Barrett V.J. , O’Brien M.M. , Moulds J.J. , Spruell P. , Jackson V. , Stubbs J.R.
Published: May 2021

Anti-Holley (Hy) has been reported as an IgG antibody occurring in previously transfused or multiparous black patients. In this case anti- Hy was identified in a 16-year-old black, primigravida female admitted at 32 weeks gestation because of premature rupture of the membranes. On admission, her blood type was determined to be A2B, D-positive and an antibody screen was negative. A second antibody screen, performed 4 days later, was positive in all three cells. Anti-Hy was subsequently identified. The antibody was reactive at room temperature, 37°C, and in the antiglobulin phase. IgG and IgM components of anti-Hy were demonstrated in the maternal serum, documenting a primary immune response. This resulted in serologic findings not previously described for anti-Hy. A direct antiglobulin test on the newborn red cells was negative and there was no clinical evidence of hemolytic disease of the newborn (HDN). A monocyte monolayer assay performed with maternal serum yielded negative results. Recent scientific information has resulted in the placement of Hy in the Dombrock blood group system. Alloantibodies to Dombrock system antigens have not been associated with severe HDN.
Immunohematology
1996;12:62–65.