bluuebunny/crossref_metadata_2025 huggingface dataset:
RESPONSE OF NOILER CHICKS TO DIETS CONTAINING VARYING DIETARY LEVELS OF LYSOLECITHIN
Authors: Ogbonna Ani, Augustine , Onyeka Onodugo, Mathew , Chukwuebuka Udeh, Valentine , Ngodoo Torhemen, Lynda
Published: September 2024

The response of noiler chicks to diets containing varying dietary levels of lysolecithin was investigated. Three hundred (300) day-old noiler chicks were used for the study. The birds were randomly allotted to five treatment groups of 60 birds each, and assigned to five treatments using a completely randomized design (CRD). The treatments were designated as follows: Treatment 1,0g lysoecithin; Treatment 2, 100g lysolecithin/100kg of feed; Treatment 3, 200g lysolecithin/100kg of feed; Treatment 4, 300g lysolecithin/100kg of feed and Treatment 5, 400g lysolecithin/100kg of feed. Each treatment group was replicated three times with 20 birds per replicate. Feed and water were provided to the birds ad libitum. Data were collected on growth parameters: live weights, weight gain, feed intake, feed conversion ratio and protein efficiency ratio, digestibility coefficients and oxidative status of birds. Results showed that significant (p < 0.05) differences existed among treatments in average daily feed intake (ADFI), total feed intake (TFI), daily protein intake (DPI), feed cost per kg, cost of daily feed intake, cost of total feed intake and feed cost per kg gain. Significant differences (p < 0.05) also existed among the dietary treatments in apparent retention (% of intake) of dry matter (DM) and in crude fiber digestibility coefficient. Supplementation of the noiler diets with lysolecithin had significant effect (p < 0.05) on glutathione reductase (GR), while superoxide dismutase (SOD), catalase (CAT), malondialdehyde (MDA), glutathione peroxidase (GPx) and glutathione (GSH) were not significantly (p > 0.05) affected by treatments. It was concluded that 100g of lysolecithin can be included in 100kg of feed to enhance feed intake, feed cost per kg gain and DM retention.
ANALYSIS OF ANTIBIOTIC CONSUMPTION IN BAMAKO HOSPITAL CENTERS WHOSE EFFLUENTS END UP IN THE NIGER RIVER
Authors: Diawara Abdoulaye , Niaré Sirima , Coulibaly Balla , Maïga Aminata , Ba Sidy
Published: September 2024

The consumption of antibiotics in hospitals in Mali is remarkable. The large hospitals at the top of the country's health pyramid are at the heart of this problem. The objective of this study remains the analysis of antibiotic consumption in five large hospitals in Bamako during 2018- 2020 and to measure the concentration of antibiotics in the Niger River through hospital effluent discharges. The penetration index was chosen as a tool to measure antibiotic exposure. It takes into account the total amount in grams of antibiotics divided by the Defined Daily Dose established by the WHO. Liquid chromatography in tandem with a mass spectrometer was used to detect and measure the concentration of antibiotics in the effluent in the environment. Three families of antibiotics, including beta-lactam (69%), fluoroquinolones (22%) and macrolides (17%), have brought hospitals together to prescribe antibiotics, in this case amoxicillin (157.6 DD/1000), ciprofloxacin (128.8 DD/1000) and erythromycin (222.4 DD/1000). Effluent concentrations averaged 6.06 μg/L of amoxicillin, 24.9 μg/L of ciprofloxacin and 1.38 μg/L of erythromycin. The occurrence of antibiotic detection was on average (> 70%).About 20% of the total antibiotic load through hospital effluent was sent directly into the Niger River; 50% via sewage systems and the rest through runoff and infiltration. Optimizing antibiotic prescribing and setting up a national network for monitoring and analyzing antimicrobial consumption are necessary to rationalize antibiotic consumption.
3-Step Risk Assessment and Dissemination Framework with CCTV Video for Crime Prevention
Authors: Kim Yeonsu , Kim Seeun , Ahn Jinho
Published: September 2024

Existing crime prediction systems have limitations in crime prevention, lack of monitoring personnel compared to the number of installed CCTV cameras, and reliance solely on conventional investigation data and experience for determining crime risk levels. To overcome these limitations, this paper introduces a novel machine learning-based CCTV video analysis and dissemination framework for crime prevention. The framework is developed for providing swift and accurate compressed data sets of CCTV videos through risk assessment and analysis algorithms for behavior and target recognition, time-based crime occurrence rates, and detection of abnormal behavior. In addition, it can resolve the blind spot issue of the traditional CCTV video systems by our breadth-first search mechanism.
Métodos de extracción de vitamina B-12 producida por fermentación: su medición microbiológica
Authors:   , Suhami Regina
Published: September 2024

I) Introducción II) La vitamina B-12: antecedentes, propiedades generales, constitución química, métodos de valoración, métodos de producción Parte experimental 1) Valoración por el método microbiológico: selección de la cepa, puesta a punto de la técnica de medición, medio de cultivo, lectura de los resultados, interpretación 2) Producción de vitamina B-12 por fermentación con Bacillus brevis 3) Extracción de la vitamina B-12 de los caldos crudos de cultivo: adsorción del material con carbón, elución de la vitamina B-12 de los adsorbatos
Υφιστάμενα εμπόδια εφαρμογής του Προγράμματος Σπουδών στο Θεματικό Πεδίο των Μαθηματικών του Νηπιαγωγείου: Απόψεις Παιδαγωγών Γενικής και Ειδικής Αγωγής
Authors: Charitaki Garyfalia , Vretudaki Helen , Kypriotaki Maria
Published: September 2024

Η παρούσα έρευνα έχει ως σκοπό της τη διερεύνηση των υφιστάμενων εμποδίων εφαρμογής του Προγράμματος Σπουδών στο Θεματικό Πεδίο των Μαθηματικών του Νηπιαγωγείου, μέσω των απόψεων των εν ενεργεία παιδαγωγών γενικής και ειδικής αγωγής. Στην έρευνα συμμετείχαν 621 παιδαγωγοί στους οποίους έγινε επίδοση του ερευνητικού εργαλείου Διδακτικής Αυτό-Αποτελεσματικότητας των Εννοιών του Θεματικού Πεδίου των Μαθηματικών στο Νηπιαγωγείο. Τα ευρήματα της παρούσας έρευνας καταδεικνύουν με σαφήνεια ότι οι παιδαγωγοί γενικής και ειδικής αντιμετωπίζουν συστηματικές δυσκολίες στην εφαρμογή του προγράμματος σπουδών για τη διδασκαλία των εννοιών του θεματικού πεδίου των μαθηματικών του νηπιαγωγείου. Επιπροσθέτως, σημαντικές φάνηκε ότι είναι οι επιδράσεις της ηλικιακής ομάδας και των ετών εκπαιδευτικής υπηρεσίας, του υψηλότερου τίτλου σπουδών που είχε στην κατοχή του/της ο/η παιδαγωγός, όπως επίσης και του αριθμού των πανεπιστημιακών μαθημάτων που ο/η παιδαγωγός έχει ολοκληρώσει στην Ειδική Αγωγή και Εκπαίδευση (ΕΑΕ). Η αξιοποίηση τεσσάρων διαφορετικών κριτηρίων κατέδειξε καλή προσαρμογή του μοντέλου δομικών εξισώσεων (CFI=.98≥0.90, RMSEA=.049≤.080, SRMR=.024<.080, TLI=.97>.95). Τα ευρήματα της έρευνας συζητούνται με άξονα την παιδαγωγική τους αξιοποίηση.
Intervención psicosocial en contextos de emergencia durante los años 2020-2021 para personas que viven con VIH/SIDA en Colombia
Authors: Restrepo Pineda Jair Eduardo , Aguirre Ocampo Dannys Alberth , Hurtado Roldan Anny Astrid
Published: September 2024

El objetivo es comprender cómo el apoyo psicosocial puede ser tanto preventivo como rehabilitador. Se realizó la sistematización de una intervención psicosocial con personas que viven con VIH/SIDA, lo que permitió visibilizar las repercusiones generadas por la pandemia y las medidas de confinamiento, adoptadas para la mitigación del Covid-19, sobre la salud física, social y mental de los sujetos participantes. En total se caracterizaron y atendieron 63 personas en situación de vulnerabilidad por ser inmigrantes o personas dedicadas al trabajo sexual. Los resultados muestran que la discriminación y los prejuicios hacia las personas que viven con VIH/SIDA se entrecruzan con la estigmatización hacia las personas que se dedican al trabajo sexual, así como los juicios de valor xenófobos y aquellos que se tienen frente a las condiciones de nacionalidad y de clase. Es indispensable que se considere en los servicios de atención para personas con VIH/SIDA, no solo la atención médica y farmacológica, sino la atención psicosocial que desempeña un papel fundamental al abordar factores como el estrés, la ansiedad, la depresión y el estigma social que a menudo enfrentan las personas con VIH/SIDA y que pueden disminuir su adherencia al tratamiento antirretroviral.
Factores determinantes de la sostenibilidad en sistemas agropecuarios de la Amazonia colombiana
Authors: Pardo Rozo Yelly Yamparli , Marlés Betancourt Claritza , Peña Torres Parcival
Published: September 2024

La sostenibilidad es un concepto multidimensional que involucra variables socioeconómicas, políticas y ambientales. La investigación tuvo como objetivo identificar los factores determinantes de la sostenibilidad en sistemas agropecuarios de la Amazonia colombiana. Se tomó una muestra de 70 fincas y se construyeron indicadores de sostenibilidad mediante el análisis de la envolvente de datos con las variables: razón beneficio costo (RBC), índice de necesidades básicas insatisfechas (INBI), carbono almacenado en la biomasa aérea, porcentaje de coberturas en bosque, suelos productivos y la percepción del productor sobre el apoyo del Gobierno (AG). Posteriormente, se empleó un modelo econométrico donde el índice de sostenibilidad estaba en función de variables de las diferentes dimensiones, cuyos coeficientes se hallaron con el método de máxima verosimilitud. En los resultados se encontró que 14 % de las fincas es sostenible y el 86 % tiene potenciales de mejora en: aumentos en la RBC, en el AG, la utilización del suelo productivo y la reducción de los costos operativos. Los factores determinantes de la sostenibilidad fueron: los gastos de la finca, el número de trabajadores y las hectáreas boscosas. Se concluye que existen sistemas agropecuarios en la Amazonia eficientes en lo socioeconómico, político y conservan mejor los servicios ecosistémicos.
COMPARATIVE ANALYSIS OF VACUUM-ASSISTED CLOSURE AND TRADITIONAL DRESSING FOR CHRONIC WOUNDS
Authors: Nagwani Akshay , Magre Nikhil , Natwarlal Vyas , Reza Ali
Published: September 2024

Introduction: Chronic wounds pose a signicant medical challenge, characterized by prolonged healing times and resistance to conventional
treatments. Effective management strategies are essential for enhancing healing outcomes and improving patients' quality of life. This study aims
to compare the efcacy of Vacuum-Assisted Closure (VAC) therapy and traditional dressing methods in the healing of chronic wounds. Material
and Methods: This prospective randomized comparative study was conducted at a tertiary care teaching hospital in Navi Mumbai, Maharashtra,
from December 2020 to October 2022. Fifty patients with chronic wounds were randomly assigned to two groups: Group Areceived VAC therapy,
while Group B received conventional dressings. Outcomes measured included hospital stay duration, healing time, and graft acceptance rates. Data
were analyzed using IBM SPSS Statistics 26.0, with a p-value of less than 0.05 considered signicant. Results: The study found that patients
treated with VAC therapy had signicantly shorter hospital stays (15.00 ± 6.00 days vs. 19.44 ± 7.05 days), faster healing times (16.48 ± 5.75 days
vs. 26.40 ± 7.26 days), and higher graft acceptance rates (83.72% ± 14.82 vs. 74.40% ± 15.21) compared to those receiving conventional dressings.
These differences were statistically signicant with pvalues of <.001. Conclusion: VAC therapy signicantly outperforms conventional dressings
in treating chronic wounds, leading to shorter hospital stays, faster healing times, and higher graft acceptance rates. These ndings support the
adoption of VAC therapy for improved patient outcomes and more efcient chronic wound management.
EFFECTS OF CORE STRENGTHENING EXERCISES ON CARDIORESPIRATORY FITNESS IN TYPE 2 DIABETICS
Authors: Arkate Shaheen , Parulekar Poonam , Fernandes Orein
Published: September 2024

This study investigated the impact of core strengthening exercises on the cardiorespiratory tness of individuals with type 2 diabetes mellitus
(T2DM). Forty participants were randomly assigned to either an intervention or a control group. Over a 4-week period, the intervention group
followed a specic core strengthening exercise regimen, while the control group received no intervention and were assessed at baseline and nal
week. Outcomes measures included VO2Max and vital capacity. Signicant improvements were observed in the intervention group compared to
the control group, as evidenced by enhanced VO2Max (p<0.01), increased vital capacity (p<0.01) and improved core strength. These ndings
suggest that targeted core exercises can potentially optimize cardiorespiratory parameters in individuals with T2DM, likely through improvements
in muscle quality, insulin sensitivity, and overall physical function.
A STUDY ON COMPARISON OF ELECTROCARDIOGRAPHIC AND ECHOCARDIOGRAPHIC EVIDENCE OF LEFT VENTRICULAR HYPERTROPHY
Authors: Paul Emmanuel , A Shilpa , Krishna Preetham Surampudi Sai
Published: September 2024

Background: Left ventricular hypertrophy (LVH) consists of an adaptive mechanism of the cardiac muscle due to an increased activity demand or
functional overload. In fact, when LVH is evaluated simultaneously by ECG and echo, discrepancies between ECG-based LVH and echo-based
LVH are observed in a certain proportion of patients. Aims&objectives: To study the evidence of LVH by electrocardiography and
echocardiography in patients clinically suspected to have LVH. Materials And Methods: We conducted a prospective observational study among
25 patients admitted in general medicine ward and medical intensive care unit. Patients were selected on the basis of clinical suspicion of
LVH.ECG and Echocardiography were done on these patients and LVH was detected after applying ECG criterias for LVH and Echocardiographic
cut off for LVH. Results: Out of the 25 patients included in this study there was male predominance with majority of them belonging to the age
group of 41-50 years. Hypertension was the most common etiology for LVH in this study. Among the ECG criteria for LVH, Cornell criteria was
found to be most sensitive criteria. Echocardiography was superior to ECG in diagnosing LVH in this study. Conclusion: Left ventricular
hypertrophy is a marker of volume/pressure overload which in turn is a marker of cardiovascular morbidity as well as mortality.ECG and
Echocardiography are the most commonly used methods for detection for LVH. Among the ECG criteria for LVH, Cornell criteria was found to be
most sensitive criteria in this study. Echocardiography was superior to ECG in diagnosing LVH in this study
PONTIC DESIGNS: PHOENIXING GINGIVAL HEALTH
Authors: Sethi Jain Harshit , Sharma Madhurima , Saxena Tulika
Published: September 2024

A pontic is an integral part of FPD that takes the role of absent natural teeth, maintains its operations, and occupies the area of the actual crown. The
absolute properties taken into application while considering pontic design are health of the periodontium, maintenance of dental health, no food
entrapment as well as occlusal harmony. Plaque accumulation involves the initiation of gingival and periodontal diseases and increases the chances
of caries activity in association to the FPD. The pontic design should be such that the area can be cleansed by tooth brushing and ossing. The
factors affecting pontic designs are the amount of the ridge resorbed, occlusal load and amount of space present for the pontic. “What you focus,
determines what you miss” - a lost tooth is always the centre of attraction, so the primary concern should be to replace the lost tooth structure1.
OPTIMIZATION OF CULTURE CONDITION FOR ANTIBACTERIAL METABOLITE PRODUCTION AGAINST STAPHYLOCOCCUS AUREUS STRAINS
Authors: Manikandan K Santhosh , Arunnachalam Kayalvizhi , Priyadarisini V. Brindha
Published: September 2024

Actinobacteria have been used for drug discovery more than ve decades, producing over 10,000 bioactive compounds. Among this ~75% are
produced by Streptomyces sp, the by far mostly explored actinomycetes genus. Actinobacteria from various sources are yet to be explored, among
them are endophytic actinobacteria, organisms that resides inside the plant tissues without causing damages to the host found to produce wide range
of secondary metabolites that are highly benicial. Optimization was one of the prime studies opted to determine the parameters that help in
enhanced production of identied bioactive secondary metabolites. Hence the present study was framed to optimize the culture conditions such as
physical and chemical parameters and to evaluate the highly inuential components needed for the antibacterial metabolite production. Optimized
media and conditions were selected to be SSY medium with pH 7 and carbon and nitrogen source of sucrose and ammonium sulphate respectively
along with salinity of less than 3% of NaCl, incubated at a temperature of 30ºC for 7 days that produce maximum zone of inhibition.
ULTRASONIC COAGULATION DEVICE VS MONOPOLAR ELECTROCAUTERY IN RESECTION OF TUMORS OF TONGUE – A RANDOMISED CONTROL TRIAL
Authors: Swathi Kiran Pattem , Srikanth Damera , Pamidi V. R. Chandrababu , Siva Ganesh Pampana , Gogineni Tarun , Nutalapati Ravi Shankar
Published: September 2024

Background: Although oral cancerous lesions are curable with surgical involvement, certain values necessitate the development of newer
techniques and newer equipment to promote the prognosis of the patient towards the long-term survival and quality of life. Forty adult Methods:
tongue cancer patients with advanced cancer staging from TNM stage 1 and 2, requiring surgical removal are included in this study and randomly
alloted into two groups. Group 1 undergoing excision with electrodiathermy and Group 2 undergoing excision with ultrasonic coagulation device.
Results: Mean duration in Monopolar cautery is 13.6 minutes whereas in ultrasonic coagulation device is 8.9 minutes. Mean blood loss in
Monopolar cautery is 160ml and blood loss in ultrasonic coagulation device is 97ml. Patients who und Conclusion: erwent excision with ultrasonic
coagulation device had wider margins and short duration of surgery when compared to monopolar cautery. Simultaneous hemostasis and cutting
are achieved with ultrasonic coagulation device – reduction in duration for primary tumor excision.
FETAL EPICARDIAL FAT THICKNESS AS A MARKER FOR GESTATIONAL DIABETES MELLITUS
Authors: B S Tejaswini , Manjunath Aditya , M U Jeevika
Published: September 2024

Aims: The study aimed to assess Fetal Epicardial fat thickness (EFT) and ascertain its role in diagnosis & effective prediction of Gestational
Diabetes mellitus (GDM) with correlation to Oral Glucose tolerance test (OGTT). A case control stud Patients and Methods: y was conducted at
J.J.M. Medical College in Davanagere, Karnataka, involving 80 pregnant women (40 GDM cases and 40 control). Patients underwent imaging
procedures -ultrasonography after 75 g OGTT results were obtained between 24 weeks + 0/6 days to 28 weeks+ 0/6 days of gestation. The Results:
study found that fetal epicardial fat thickness (EFT) was signicantly higher in the group with gestational diabetes mellitus (GDM) compared to the
control group without GDM. Additionally, the increased EFT showed a positive association with serum glucose levels from the 2-hour oral glucose
tolerance test (OGTT), demonstrating high sensitivity and specicity. The study underscores the sig Conclusion: nicance of the Fetal EFT as a
useful marker for early prediction of GDM and identify early changes in fetal metabolism before accelerated fetal growth and polyhydramnios is
apparent.
AN IN-VITRO STUDY ON THE COMPARATIVE EVALUATION OF SURFACE ROUGHNESS IN PMMA (POLYMETHYL METHACRYLATE) DENTURE BASES INFUSED WITH ZIRCONIA AND GRAPHENE
Authors: Nirgude Akshata , Sharma Alok , Khetan Jitendra , Mahjan Namrata , Bhende Minal , Sonawane Arati
Published: September 2024

Surface roughness is a critical parameter inuencing the quality and performance of dental prosthetic materials. This study investigates the impact
of incorporating zirconium and graphene oxide into poly (methyl methacrylate) (PMMA) composites on surface roughness characteristics. Three
distinct groups of PMMA composites—Pink, Light Pink, and Grey—were analyzed, revealing unique surface properties associated with each
group. Group B (Light Pink) exhibited the most extensive surface roughness values, suggesting distinct material characteristics. The research
explored the effects of zirconium oxide and graphene oxide additives on PMMA composite surface roughness. Results indicated that while
zirconium oxide incorporation led to higher average roughness values and increased variability, graphene oxide caused a slight reduction in
average roughness with a narrower condence interval, implying more consistent outcomes. Furthermore, statistical analyses revealed signicant
differences in surface roughness when comparing PMMA composites containing zirconium oxide to those with graphene oxide. Zirconium oxide
additives notably increased surface roughness compared to the control group, whereas graphene oxide did not induce signicant changes. Overall,
this study highlights the inuence of additive type—zirconium oxide versus graphene oxide—on the surface properties of PMMA composites.
These ndings contribute valuable insights into material selection and formulation for dental prosthetic applications, emphasizing the importance
of understanding how different additives affect surface roughness and, consequently, the functional and aesthetic qualities of dental restorations.
Such knowledge is crucial for optimizing the design and performance of dental prosthetic materials to meet the diverse needs of patients and
practitioners in prosthodontics.
Hepatosplenic T-Cell Lymphoma in an Immunocompetent Young Female: A Diagnostic Challenge
Authors: Singh Dr. Rachana , Votterry Dr. Ravindra , Dr. Milap Dr. Milap , Afroz Dr. Seema
Published: September 2024

Hepatosplenic T-cell lymphoma (HSTCL) is a rare T-cell neoplasm, most commonly arises from a small subset of γ/δ T-cell receptor–expressing lymphocytes and forms less than 1% of all non-Hodgkin's lymphomas. HSTCL is more common in adolescent and young adults and has a rapidly progressive clinical course and poor outcome due to its refractoriness to conventional chemotherapy regimens. The rarity of this disease, along with lack of nodal involvement and presenting symptoms that mimic different entities including infectious aetiologies, makes this lymphoma a significant diagnostic challenge. To place emphasis on the challenges encountered in establishing the diagnosis, here in, we present a case of a 29-year-old-female who presented with asymptomatic pancytopenia and massive splenomegaly. After an elaborate workup, and extensive investigations, which all turned out to be negative, a combination of morphologic finding of atypical lymphoid cells in the bone marrow, typical immunophenotypic profile on flow cytometry and the pattern of involvement of the bone marrow biopsy, were a key in diagnoses. The report of this case is an effort to emphasize the high index of suspicion for timely detection of such a rare entity.
Dermoscopy of Lymphangioma Circumscriptum
Authors: Zineb Fajri , Baybay Hanane , Soughi Meryem , Douhi Zakia , Elloudi Sara , Mernissi Fatima Zahra
Published: September 2024

Background: Cutaneous lymphangiomas are congenital lymphatic malformations, which may involve the skin and subcutaneous tissue and can occur on any cutaneous surface or mucous membrane. Cutaneous lymphangiomas are uncommon, accounting for 4% of all vascular tumours. Dermoscopy is a non-invasive technique, which has greatly improved the diagnostic of cutaneous lymphangiomas. Objective: Our aims were to describe the different dermoscopic patterns of lymphangioma circumscriptum. Methods: We performed a descriptive retro-prospective observational study that included all patients diagnosed with DM in dermatology department over 2 years from 2019 to 2021. Results: A total of 14 cases of lymphangioma circumscriptum were studied. Ranging in age from 3 to 38 years. The most common structure we found in lymphangioma circumscriptum was the presence of lacunae, which were found in 12 of patients (85%) These lacunae were red or dark in colour in 6 cases (50%), yellowish or whitish in 5 cases (35,7%) and multicoloured (yellow, white, red and white in the same patient) in 4 cases (28%).The second most common dermoscopic structure was the presence of vascular structures, which were found in 82% of patients .Other dermoscopic structures were white lines, found in 9 cases (64%) ,the hypopyon sign or two-tone lacunae in 4 (28%). Conclusion: Recognition of dermoscopic features of eybrow trichotillomania is very important and could help to diagnosis of lymphangioma circumscriptum.
MULHER EM SITUAÇÃO DE VIOLÊNCIA DOMÉSTICAS: ÓTICA DOS PROFISSIONAIS DE SAÚDE
Authors: De Oliveira Adriely , Marcheti Priscila Maria , Rigatto Renata , Da Mota Cirqueira Geni , Coronato Fernandes Mariana , De Sousa Nóbrega Maria do Perpétuo Socorro
Published: September 2024

Introdução: A Atenção Primária em Saúde desempenha um papel crucial no atendimento de mulheres em situação de violência doméstica, sendo a porta de entrada para as usuárias. Objetivo: compreender a percepção de profissionais da saúde sobre o atendimento às mulheres em situação de violência doméstica. Metodologia: Estudo qualitativo descritivo-exploratório, realizado em agosto de 2023 com 20 profissionais de saúde em Campo Grande, Mato Grosso do Sul. Resultados: Os profissionais revelaram desconhecimento sobre como lidar e de fluxo existente no município, dificuldades no atendimento das mulheres vítimas de violência doméstica e estratégias para conduzir o atendimento às mulheres vítimas de violência doméstica. A subnotificação da violência doméstica é atribuída à inexperiência e falta de capacitação dos profissionais, além de obstáculos como estrutura física inadequada e sobrecarga de trabalho. Considerações finais: Sugere-se a reflexão sobre a criação de um fluxograma na Atenção Primária em Saúde, protocolos orientadores, o desenvolvimento contínuo de ferramentas e capacitações e mais pesquisas são essenciais.
DESAFIOS PARA ADOÇÃO DAS PRÁTICAS DE GESTÃO DE PESSOAS EM ORGANIZAÇÕES PÚBLICAS
Authors: Montezano Lana
Published: September 2024

As organizações públicas devem adotar práticas de gestão de pessoas que contribuam para disponibilidade de profissionais com perfil adequado e engajado para gerar uma prestação de serviços públicos de qualidade. No entanto, existem variáveis contextuais que podem dificultar o uso de melhores práticas da literatura no contexto de organizações públicas. Objetivo: identificar os desafios para adoção das práticas de gestão de pessoas no setor público. Métodos: A pesquisa é descritiva, transversal, com abordagem qualitativa, a partir de dados coletados com pergunta aberta em um questionário eletrônico respondido por 34 alunos de mestrado profissional em administração pública que possui experiência média de 19 anos no setor público e de 7,7 anos com gestão de pessoas. Os dados foram consolidados com nuvem de palavras e análise de conteúdo de Bardin. Resultados: Foram identificadas cinco categorias temáticas e 21 subcategorias de desafios: barreira do comportamento organizacional (com 3 subcategorias); falta de preparo para adoção de práticas (com 2 subcategorias); falta de suporte organizacional (com 4 subcategorias); limitações inerentes ao contexto do setor público (com 2 subcategorias),, limitações nas práticas de gestão de pessoas (com 10 subcategorias) Conclusões. O estudo evidenciou aspectos contextuais das organizações públicas que tem dificultando a adoção de práticas de gestão de pessoas de forma mais efetiva, além de identificar quais as principais dificuldades nas práticas em si, o que pode contribuir com os gestores para estabelecer ações de superação destes desafios. O método qualitativo permitiu obter informações relacionadas ao tema que não estavam previstas inicialmente na coleta, mas que emergiram das respostas dando maior riqueza para compreensão do fenômeno estudado.
Diet control and BMI impact on Metformin response in type 2 Diabetes mellitus patients
Authors: AL-Hussain Naem Alaa Abd , Ghafil Fadhaa Abdulameer , Al-Terehi Mona N. , Majeed Sahar , Al-Mudafer Defaf , Hadi Najah Rayish
Published: September 2024

Aim: To assess the impact of BMI and diet control on variation in response to metformin monotherapy in Iraqi people with type 2 DM.
Materials and Methods: a cross-sectional study included 150 patients who met specific criteria, such as being between 30 and 70 years old, diagnosed with type 2 diabetes, and on a daily dose of 1000 mg metformin as a monotherapy for at least three months. Data collected included body mass index (BMI) and glycemic control parameters such as: glycated hemoglobin (HbA1c) levels, fasting blood glucose levels, fasting serum insulin levels, HOMA-IR, and insulin sensitivity. The patients according to their metformin response classified into two groups based on HbA1c as following: poor (HbA1c≥6.5% and good (HbA1c≤6.5%) responder’s patients.
Results: The statistical analysis suggests that there is no meaningful distinction in glycemic control parameters when comparing good and poor responders within specific BMI subgroups and among individuals practicing diet control. However, in a broader context, it is evident that glycemic control parameters tend to be lower in patients with lower BMI and those who are following a controlled diet.
Conclusions: The correlation between diet control and BMI with glycemic control in diabetic patients, underscoring the significance of lifestyle adjustments in the management of diabetes.
Three cases of fatal postoperative thromboembolic complications in patients with liver cirrhosis and bleeding from esophageal varicose veins after COVID-19
Authors: Rudyk Diana V. , Tutchenko Mykola I. , Chub Sergiy L. , Besedinskyi Mykola S.
Published: September 2024

Coronavirus disease (COVID-19), which broke out in China and caused a devastating pandemic worldwide, is associated with a significantly increased risk of thrombotic complications, especially pulmonary embolism. During the COVID-19 pandemic, investigations have reported a high incidence of venous thromboembolic (VTE) events in hospitalized patients with COVID-19, often despite thromboprophylaxis. Current recommendations for thromboprophylaxis are based on randomized clinical trials, which usually exclude patients at а potentially high risk of hemorrhagic complications. This category includes patients with liver cirrhosis complicated by variceal bleeding, thrombocytopenia, and coagulopathy. We present three patients who suffered severe covid pneumonia and were hospitalized with acute variceal bleeding, who developed fatal thromboembolic complications in the postoperative period.
In silico analysis for the proposal of new drugs against the phosphoprotein nucleocapsid of the severe acute respiratory syndrome coronavirus 2 virus
Authors: de Souza Amanda Bubula , de Araújo Leonardo Pereira , Morais Amanda Almeida , Santos Leandro Marcos , Santos Yana Cristina Albanez , Lopes Cássia Milene Ribeiro , de Carvalho Paulo Vinicius Sanches Daltro , Hassan Syed Shah , da Silveira Nelson José Freitas
Published: September 2024

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which began in late 2019, has resulted in approximately seven million deaths worldwide. This underscores the urgent need for vaccine and drug development. In silico techniques, especially molecular docking, provide promising means for discovering new treatments. This study aimed to identify novel compounds with potential activity against the nucleocapsid protein of SARS-CoV-2 using drug repositioning and bioisosterism techniques. We performed molecular docking with 20,115 compounds from the BindingDB database. The protein, obtained from the Protein Data Bank (PDB ID: 6WZQ), was prepared using MGLTools software, including protonation and removal of co-crystallized ligands and water molecules. We defined the binding site at the protein’s active site and used AutoDock Vina software for molecular docking, ranking the results based on relative binding energy. Interactions were visualized using Pymol and LigPlot+ software, focusing on hydrogen bonds and hydrophobic interactions. Compound BDBM6732 showed the most favorable binding energy (−13.4 kcal/mol), similar to the control compound suramin (−13.3 kcal/mol), but it was predicted to carry risks for hepatotoxicity and mutagenesis. We generated bioisosteres, resulting in two candidate analog compounds with superior affinity to four compounds referenced in the scientific literature, two of which had their activity validated in in vivo testing. These results suggest that the two analogs may potentially combat SARS-CoV-2 by binding to the nucleocapsid protein. However, validation in both in vitro and in vivo settings is essential.
Advancing Sustainability in Organic Coffee Production: A Comprehensive Analysis of Research Trends, Challenges, and Future Opportunities
Authors: Parrales-Reyes Jenny , Escobar-Molina David , Rengifo-Lozano Raúl A. , Espinoza-Vásquez Gladys , Martínez-García Víctor M. , Díaz-Romero Yennifer , Saltos-Buri Viviana , Salazar-Ponce Erick , Cañarte-Quimis Luz T. Y. , Rincón-Guio Cristian
Published: September 2024

This paper presents a comprehensive analysis of the research landscape surrounding organic coffee production and its alignment with sustainability principles. Utilizing a structured protocol focused on the Scopus database, an initial identification of 289 documents was refined to 108 for in-depth analysis. Through a bibliometric analysis of publications from 2000 to 2024, key trends, authors, and geographical distributions are identified, highlighting the growing academic interest in sustainable coffee practices. The co-occurrence network analysis reveals the thematic structure of the literature, focusing on environmental sustainability, agricultural practices, geographical focus, and economic and social dimensions. Content analysis further underscores the importance of shade-grown coffee systems, climate-smart agriculture, and sustainability certifications in promoting ecological and economic resilience in coffee-producing regions. However, the study also identifies significant challenges, such as the mixed effectiveness of sustainability certifications and the environmental impacts of conventional coffee farming. The paper concludes by outlining research opportunities in climate adaptation, technological innovation, and the socio-economic dynamics of coffee supply chains. The findings emphasize the need for a holistic approach that integrates environmental, social, and economic dimensions to achieve truly sustainable coffee production.
 
Received: 16 July 2024 / Accepted: 31 August 2024 / Published: 05 September 2024
Bitcoin Prices on the Volatility of Environmental, Social and Governance (ESG) Indices
Authors: Danila Nevi , Noreen Umara , Aggarwal Priyanka
Published: September 2024

Cryptocurrencies have exploded in popularity since the launch of Bitcoin in 2009 and are collectively worth over $1 trillion. Despite its prevalence, the impact of Bitcoin on traditional financial markets and its influence on other asset classes, such as Environmental, Social, and Governance (ESG) indices, remains unexplored. The current paper focuses on determining the impact of bitcoin prices on the volatility of ESG indices. We use data from the Dow Jones Sustainability Indices family, such as DJSI World (DW), DJSI North America (DNA), DJSI Europe (DE), DJSI Asia Pacific (DAP), and DJSI Emerging Market (DEM). Data was collected for the period from 2012 to 2023. The CBOE market volatility index (VIX) is included to increase the scope of our study. For estimation purposes, Westerlund & Narayan's (2015, 2012) distributed lag model was used to explore the relationship between the realized volatility of ESG index and bitcoin prices. Results indicate that bitcoin prices have no interconnectedness with ESG indices volatility. Further, the correlation between the volatility index (VIX) and ESG indices reveals a negative relationship, strengthening model findings. The bitcoin market is modest; however, ECG indices cover a wide range of industries and sectors, leaving it less vulnerable than the bitcoin market. The findings provide empirical bases to the investors for optimal portfolio allocation. 
 
Received: 5 May 2024 / Accepted: 22 August 2024 / Published: 05 September 2024
Feminine Expectations from a Gender Perspective in Peruvian Television Fiction
Authors: Alarcon-Llontop Luis-Rolando , Martínez Evelyn Noelia Sotomayor , Pasapera-Ramírez Sindy , Torres-Mirez Karl , Cornelio Francisco Javier Barquero
Published: September 2024

The study addresses the view of women leaders of Peruvian civil society organizations (CSOs) on the representations of women in series/soap operas broadcast by national free-to-air television. From the naturalistic paradigm and a qualitative approach, following a phenomenological and grounded theory design, it covered three pre-categories: the concept of gender, gender relations, and gender system. Focus groups were used to talk to 39 women community leaders, educators, and cultural leaders in two Peruvian cities. It is concluded that they perceive in the series/ soap operas of national television fiction, that they only obey market demands, without innovations in showing women, structures of inequality in the representations and roles, unfair for them, not in line with reality, and that are reinforced by rules and norms of the traditional and religious social base; and, in their gender perspectives, still under construction, they do not yet integrate into the LGTBQ+ community. The evidence indicates a growing concern for increased female representation and inclusion in television. This presents a challenge for both the government and television companies. Peruvian feminism must align with modern perspectives on this trend, presenting an opportunity for activism.
 
Received: 4 June 2024 / Accepted: 29 August 2024 / Published: 05 September 2024
Lexico-Semantic Features of the Albanian Language in Written and Online Media
Authors: Jani Greta
Published: September 2024

In this study, the impact of print media on the development and transformation of the Albanian language's lexicon and semantics will be investigated. Focusing on several issues of the local newspaper "Boulevard" from the city of Durrës, Albania, this paper analyzes the role that this newspaper and its sections have played in enriching the Albanian vocabulary and the semantic changes of its words. Through the analysis of various articles and materials published in this newspaper, the study identifies the introduction of new words, the influence of borrowings, and the evolution of the meanings of traditional words in different social and political contexts. Additionally, the effects of technology and digital media on the transformation of the lexicon and semantics are explored. The results of this study demonstrate that this widely read print media in the city and beyond plays a significant and ongoing role in preserving and enriching the Albanian language, reflecting, and shaping the cultural and social dynamics of the time.
 
Received: 21 July 2024 / Accepted: 28 August 2024 / Published: 05 September 2024
RESPONSIBILITY OF INFLUENCERS WHO CONDUCT STOCK POMMS AS A LAW ENFORCEMENT MEASURE FOR INVESTORS
Authors: Edelweiss Agatha , Emmanuel Joanne , Siregar Ricky
Published: September 2024

Many stock investment influencers often engage in stock pumping and dumping on social media. "Pompom" is a term for "pump and dump" which involves individuals or groups. Those involved in stock pumping and dumping frequently share information about stocks they already own or plan to buy. This indirectly shapes opinions and captures the attention of their followers to buy stocks as per their desires, often enhanced by enticing details. This attracts people to invest in the recommended stocks. Pompom influencers target millennial and novice stock investors, as these groups seek quick and substantial profits. When millennial and novice investors begin purchasing stocks, they often expect only gains without considering potential losses. Due to their limited knowledge, beginners often rely solely on the provocations from stock-pumping influencers on social media to make decisions about which stocks to buy. They may skip technical and fundamental analysis of the companies behind the stocks they purchase. This means they don't investigate whether these pompom influencers have conducted thorough assessments of the recommended stocks through social media. Those involved in stock pumping can be held accountable under securities laws and criminal codes.Keywords: stock investment law, stock influencers, pump and dump
THE PRINCIPLE OF GOOD FAITH IN COLLECTIVE LABOR AGREEMENTS BETWEEN EMPLOYERS AND LABOR UNIONS IN REVIEW OF CONTRACT LAW
Authors: Safrida Safrida
Published: September 2024

The principle of good faith is an important principle in contract law and is accepted in various legal systems, but until now the doctrine of good faith is still controversial Good faith is known by 2 (two) phases, namely the pre-contract phase and the contract execution phase. The pre-contract phase is called subjective good faith, which means that good faith is more directed towards honesty, while good faith in the contract implementation phase is called objective good faith, which means that good faith is interpreted as appropriateness and decency or justice. A work agreement is an agreement between workers/laborers and employers or employers that contains working conditions, rights and obligations for the parties. The definition of working conditions is the rights and obligations of employers and workers that have not been regulated in laws and regulations. Work agreements made must not conflict with existing labor agreements or Collective Labor Agreements (KKB)/Collective Labor Agreements (PKB). This research uses normative legal research sourced from secondary data related to the research topic, secondary data that has been systematically arranged and then analyzed qualitatively. From the research conducted, it was found that the position of the principle of good faith is very important not only at the stage of making (signing) and post-making (implementation) of the contract, but also at the pre-making (drafting) stage of the contract because in the practice of contract law the judge does use his authority to interfere with the contents of the contract. The legal consequences of a collective bargaining agreement that does not contain the principle of good faith are that if the subjective requirements concerning the subject of the CBA are incomplete, or in other words the requirements that must be met are not appropriate for those who want to make a CBA, then the CBA that has been made can be requested for cancellation by the trade union/labor union. If the cancellation is not requested by both parties concerned, then the PKB remains valid for the parties. The first legal effort made by PT United Rope with the labor union is by way of deliberation to reach consensus first, although in dispute resolution if there is no good faith in the collective labor agreement is through 2 (two) systems, namely first, non-litigation / outside the industrial relations court, namely bipartite settlement, mediation, conciliation and arbitration, while the second settlement is litigation.Keywords: Good Faith, Collective Labor Agreement; Businessman; Labour Union
IMPLICATIONS OF IMPLEMENTING MEDIATION AS A MEANS OF DIVORCE CASE SETTLEMENT
Authors: Aulia Zavira , Mia Mia
Published: September 2024

Mediation is a humane and fair way of resolving disputes as an alternative to dispute resolution (ADR) because mediation in making decisions through a peace agreement allows the disputing parties to maintain a harmonious and fair relationship. After all, both parties can negotiate a settlement. to solve problems, and the result is a win-win solution. As the organizer of the Supreme Court of the Republic of Indonesia, the Supreme Court has provided several ideas to facilitate the process of resolving disputes in court to obtain the best results. A fairly progressive idea is to optimize mediation institutions in resolving civil cases. Mediation in the Religious Courts is a bridge, a process of conciliation efforts between couples who file for divorce. In divorce mediation, this procedure is carried out by an appointed judge by a religious court.Keywords: Divorce, Effectiveness, Settlement of Divorce Cases Through Mediation
Faktor-Faktor Yang Mempengaruhi Minat Mahasiswa FEBI UINSU Dalam Menggunakan Uang Elektronik Pada Aplikasi Dana
Authors: ‘Alimah Nur , Marliyah Marliyah , Fadhila Rahma Tri Inda
Published: September 2024

The development of Information Technology and communication affects changes in the way of transactions, from the payment system using cash itunai Ike payment instrument inon itunai i(electronic ipayment isystem). this article provides acceleration in ibertransaction iterhadap imasyarakat iluas ipada umum. The use of an effective electronic ipayment system will have an impact on the reduced use of iunai I iignifikan money in itransaksi imahasiswa. This study aims to determine the influence of various expectations of work, business expectations and social influence on student interest in using the iDANA application. this research uses an analytical approach with a population of i5. 014 and uses icluster irandom isampling technique, which means that the use of random sampling is done by sending iform filling I random isesioner ike I the Ifebi iuinsu student image. isampled in this research i98 number iorang imahasiswa iFEBI iUINSU. The results of the research showed that isimultan using iuji if ivariable iEkspektasi performance, iekspektasi iUsaha idan I isosial ikerpaktur isignifkan iterhadap imahasiswa iFEBI iuinsu iekspektur iaplikasi iDANA. Iexpektasi performance imemiliki I influence ipositif iterhadap iMinat iminat iminat iminat iminat I0,320, iexpektasi performance imemiliki ipositif iterhadap iminat iminat I0, 320, iexpektasi iUsaha imemiliki inisai ipositif iterhadap Iminat iminat I0, 203. With this ir iSquare isebesar i0, 636 which means that the expectations of work, business expectations and social influence affect the interest of Ifebi iuinsu students isebesar i63, 6%.
Analisis Disiplin Kerja Pegawai Negeri Sipil di Sekretariat Daerah Kantor POLDA Sumatera Utara
Authors: Annisa Moza , Ramadhani Sri
Published: September 2024

Employee performance must be considered because it is one of the keys to success. If an agency carries out agency activities with poor performance, the agency's image will be unfavorable. According to Law Number 5 of 2014 Concerning the Principles of Civil Service, it gives the understanding that a Civil Servant is every citizen of the Republic of Indonesia who has fulfilled the specified requirements, is appointed by an authorized official and entrusted with other state duties, and is given employee benefits based on statutory regulations. -applicable invitations. In this case, discipline is a process used to deal with performance problems.