bluuebunny/crossref_metadata_2025 huggingface dataset:
Examining Neocolonialism in International Branch Campuses in China
Authors: Xu Zhenyang
Published: March 2022

The number of International Branch Campuses (IBCs) is increasing at a striking rate in Global South nations; however, structures that privilege colonizing countries arguably continue. On one hand, IBCs are considered by some scholars as a neocolonial expansion. On the other hand, IBCs are welcomed by many Global South shareholders since IBCs are considered a new model of world-class education that can contribute to local contexts. Nevertheless, Western knowledges and values can also be difficult to resonate with the receiving countries due to different social and political environments. In this paper, I first argue that a neocolonial attitude is embedded in the nature of Western IBCs in China through the framework of mimicry and resistance. Then, I raise questions concerning how shareholders in China legitimize IBCs as a supplementary form of Chinese higher education. Finally, I argue that IBCs risk the reproduction and reinforcement of coloniality and Western privilege in global contexts.
A Comparison between Pedagogical Approaches in UK and China
Authors: Zhang Bowen
Published: March 2022

With globalization increasingly define the world, international students are undertaking an important agentic role in terms of communicating different cultures. Therefore, their experiences are significant in revealing the pedagogic practices between different country settings. This article attempts to compare pedagogic practices between the UK and China by examining their cultural origins and the potential connections with pedagogical assumptions, placing on a spectrum of teacher/learner-centered pedagogy. Combining with the perspective of Chinese international students who have been studying in the UK, it captures the lived experiences of the actual classroom differences experienced by these students. It concludes with each pedagogy has its benefits and drawbacks respectively, and has its cultural fits, therefore, it is not possible for one particular educational system to completely 'borrow' pedagogic practice.
Reimagining Global Partnerships in Higher Education through Open Systems Theory
Authors: Adams Katherine , Lanford Michael
Published: March 2022

Although global higher education partnerships can promote greater intercultural understanding, establish unique environments for student and faculty development, and generate opportunities for innovative and entrepreneurial ventures, they can be beset with problems that negate their potential effectiveness. This paper proposes that open systems theory offers a constructive lens for reimagining global higher education partnerships so that they not only benefit internal stakeholders, but also society. It begins with the basic concepts associated with systems theory, with particular attention to the differences between rational and natural systems, as well as open and closed systems. To project how open systems theory might encourage global partnerships to embrace institutional outreach with the environment, the relationship of open systems theory with community engagement is then explored. Finally, the paper shows how boundaries can be either reinforced or traversed through deliberate buffering, bridging, and boundary spanning strategies.
Legacy-Innovation Challenges in Post-Soviet Higher Education: Scholars’ Academic Transformation in Cambodia and Kazakhstan
Authors: Ros Vutha
Published: March 2022

The collapse of the Soviet Union has dramatically impacted the work of scholars across the post-Soviet space. As their higher education systems have been transforming from the Soviet model of higher education, they have had to adapt themselves to maintain their academic work and career. This doctoral project compares the lives of scholars in Cambodia and Kazakhstan who lived as students and scholars under the influence of Soviet imperialism. As guided by the framework of legacy-innovation tensions and theory of accumulative advantage, interviews with nine Cambodian and eight Kazakh scholars were conducted to shed light on how they strategically dealt with transformational challenges to create opportunities for their academic work and career. This study shows that their strategies for pursuing academic careers rely on their achievement during the Soviet time to grab opportunities. Meanwhile, these strategies were also influenced by local contexts.
Peculiarities and Paradoxes of Neoliberal Higher Education in Kazakhstan
Authors: Robertson Douglas , Bayetova Nazgul
Published: March 2022

This article discusses the expression of neoliberalism in Kazakhstan’s emerging higher education system. The central tenets of neoliberalism are briefly articulated. Noted is the phenomenon that the general political-economic paradigm of neoliberalism differs in its specific implementation depending on the particular countries and cultures in which it is manifesting. In Kazakhstan, neoliberalism’s expression in the former Soviet Republic’s emerging higher education system presents five paradoxes: (a) nationalistic globalism, (b) regulated non-regulation, (c) giving as a means to getting, (d) communal individualism, and (e) developmental demise. This article explores each of these five paradoxes.
Decolonization and Transformation of Higher Education for Sustainability
Authors: Lin Jing , Stoltz Angela , Aruch Matthew , Rappeport Annie
Published: March 2022

This article argues that institutions of higher education (IHEs) require a fundamental paradigm shift toward an Indigenous Knowledge (IK) model inclusive of Indigenous Peoples, perspectives, and values. This model acknowledges the sacred value of nature, the rights of non human species, and the power and potential of transformative learning via collaboration with Indigenous communities. Through four personal experiences from one IHE, we highlight challenges and opportunities to decolonize higher education across the domains of policy, research, teaching, and programs. Examples include the Graduate Student Government's resistance to university policies of unsustainable construction projects; incorporating IK from Eastern traditions and world spiritual practices into course curriculum; Indigenizing higher education courses and projects through inclusion and collaboration with local Indigenous tribal members; and finally, ongoing transnational research and education collaborations with an Indigenous Mebêngôkre-Kayapó community in the Brazilian Amazon.
La vida de Paul, la obra de Diego: literatura de exilio en las manos de Paul Engel y Diego Viga
Authors: Schlenker Alex
Published: March 2022

A partir de varios contextos históricos y con ayuda de su autobiografía, este artículo elabora una cartografía de las zonas de contacto entre la vida y la obra del escritor judío de origen austríaco Paul Engel, quien bajo el pseudónimo de Diego Viga publicó durante su exilio en Colombia y Ecuador una veintena de novelas, un centenar de cuentos y varios títulos de ensayo y teatro entre las décadas de 1930 y 1980.
El Rincón de los Justos en Pulp Lux
Authors: Ríos Pamela
Published: March 2022

El Rincón de los Justos (1983) de Jorge Velasco Mackenzie, escritor guayaquileño, permea las fronteras de la alta cultura y de la cultura popular. Esta hibridez responde a varios factores económicos, políticos y estéticos de la modernidad. La novela nos ofrece una ruptura radical de las fronteras entre lo elitista y lo pop, lo serio y lo festivo, el canon y el margen. También, nos invita a pensar una crítica por fuera de los héroes y los grandes relatos dando cuenta del auge de lo doméstico y cotidiano. Esta desacralización de lo que se ha venido haciendo en la literatura nacional amerita recategorizar algunos conceptos. Eloy Fernández Porta llama afterpop a la literatura del nuevo milenio y en su libro Homo Sampler adjudica al bucle temporal la nueva forma de concebir el tiempo. La novela de Velasco Mackenzie se presenta adelantada a su época. La ciudad otra, la lengua otra, la contraescritura, el cambio de perspectivas y, sobre todo, la transformación del fragmento para hacer del cómic, del folletín o de las revistas por entregas, la base estructural que convierten a El Rincón de los Justos en una de las novelas más importantes de la literatura ecuatoriana.
Los guandos, caminos que se bifurcan
Authors: Landín Ramírez Tatiana
Published: March 2022

Este artículo explora los ejes temáticos de la novela Los guandos escrita por Joaquín Gallegos Lara y Nela Martínez en 1935 y 1982, respectivamente. La revisión del corpus de esta obra literaria muestra a una Nela Martínez narradora que aprovecha el material inicial del primer autor para plasmar sus vínculos y comprensión del indígena. A través de un lenguaje poético y de un evidente pensamiento político-social, Nela transforma la propuesta del primer autor al dar protagonismo a las voces indígenas subalternizadas. La autora desarrolla una posibilidad otra que resalta el mundo indígena y sus luchas reivindicativas.
Jorgenrique Adoum: autobiografías imaginadas. Entre Marx y una mujer desnuda y Ciudad sin ángel
Authors: Silva Andrés
Published: March 2022

La obra literaria del ecuatoriano Jorgenrique Adoum está caracterizada por la alteración del lenguaje y su intención reiterativa de describir la “otra realidad”, esa que permite escuchar la voz de los seres humanos desplazados y silenciados por la sociedad y por la historia. Así mismo, en el acto de reiterar, Adoum establece un tejido transtextual en su obra que permite rastrear conexiones entre géneros literarios, distintos períodos de escritura del autor y temas constantes en su obra. ¿Qué función cumple la escritura a lo largo de la vida de Adoum? Este texto apuesta por dar testimonio de su vida a través de autobiografías imaginadas que permiten, en la otra realidad, la restitución de los ausentes de la realidad oficial injusta y fracturada.
Factors associated with low back pain in workers’ health
Authors: Mesquita Mariana Araújo Santos , Chagas Kleynara Ferreira das
Published: March 2022

Introduction: Low back pain or low back pain is described as a public health problem worldwide. The high incidence of low back pain is associated with work activities, since in this environment postural standards are adopted with permanence for long periods, causing damage to workers' health, which causes a reduction in productivity, absenteeism and significant interference in quality of life. This study aimed to identify the main factors responsible for the onset of low back pain in workers. Objective: The aim of this study was to investigate scientific publications that related the contributing factors for the emergence of the etiology of low back pain in the work environment. Methodology: A search was performed in the Google Scholar, SciELO and Lilacs databases, in the periods of July and August 2021, using the following keywords: Low back pain, low back pain, sedentary lifestyle, Functionality. Studies published in the last ten years were selected, and 2,890 results were found, where of these 18 were selected for full reading and 5 contemplated in the present study, as included in the objectives of this research. Results: The studies reviewed in this research find some factors as being the most associated with the onset of low back pain in the worker, which are: sedentary lifestyle or physical inactivity, as well as the vicious posture, age and function developed by the worker. Considerations: The labor environment creates a favorable ambience for the appearance of low back pain, since this provides functional limitations and consequently a decrease in the quality of life of workers. It is emphasized the need for further research, with a greater number of articles researched or reviews, in order to explore in more detail these factors of relationship with low back pain in workers, as well as the main functional repercussions on their lives.
Fatores associados à lombalgia na saúde do trabalhador
Authors: Mesquita Mariana Araújo Santos , Chagas Kleynara Ferreira das
Published: March 2022

Introdução: A dor lombar ou lombalgia é descrita como um problema de saúde pública em um âmbito mundial. A grande incidência da lombalgia está associada às atividades laborais, já que nesse ambiente são adotados padrões posturais com permanência por longos períodos, ocasionando prejuízos para a saúde do trabalhador, o que ocasiona redução na produtividade, absenteísmo e interferência significativa na qualidade de vida. Este estudo teve como questão norteadora identificar quais os principais fatores responsáveis pelo surgimento da dor lombar no trabalhador. Objetivo: O objetivo do presente estudo foi investigar publicações científicas que relacionavam os fatores contribuintes para o surgimento da etiologia da dor lombar no ambiente laboral. Metodologia: Foi realizada uma busca nas bases de dados Google Scholar, SciELO e Lilacs, nos períodos de julho e agosto de 2021, utilizando as seguintes palavras-chave: Dor lombar, Lombalgia laboral, Sedentarismo, Funcionalidade. Foram selecionados trabalhos publicados nos últimos dez anos, sendo encontrados 2.890 resultados, onde destes 18 foram selecionados para leitura íntegra e 5 contemplados no presente estudo, conforme incluísse os objetivos desta pesquisa. Resultados: Os estudos revisados nesta pesquisa constatam alguns fatores como sendo os mais associados ao surgimento da lombalgia no trabalhador, sendo eles: o sedentarismo ou inatividade física, bem como a postura viciosa, idade e função desenvolvida pelo trabalhador. Considerações: O âmbito laboral cria uma ambiência favorável para o aparecimento de lombalgias, já que esta propicia limitações funcionais e consequentemente queda na qualidade de vida dos trabalhadores. Ressalta- se a necessidade de mais pesquisas, com um quantitativo maior de artigos pesquisados ou de revisões, a fim de explorar de forma mais detalhada esses fatores de relação com a dor lombar em trabalhadores, bem como as principais repercussões funcionais na vida destes.
The Impact of Sociodemographic Variables on Risk Factors Associated with Ischaemic Stroke Patients by Age Group
Authors: Loh Hong Chuan , Kwan Jia Ni , Ramlee Siti Nur Liyana , Looi Irene
Published: March 2022

This study aims to identify the relevant risk factors based on different sociodemographic backgrounds among ischaemic stroke patients in relation to age. We included all adult ischaemic stroke patients from 1st January 2013 to 31st December 2019 who presented to Hospital Seberang Jaya. The study utilized data that were collected from medical records and were presented with descriptive and inferential statistics.
Guarding the mind: Psychological tools can protect the mind from false information and manipulation on the internet. Here is how.
Authors: Dumalag Yandrickx
Published: March 2022

In the midst of a deadly pandemic, what could be more hopeful than hearing about the approval of an effective vaccine? Unfortunately, this good news has been overshadowed by harmful skepticism caused by widespread false information and manipulation on the internet. A lot of people are refusing to get vaccinated based on information they are exposed to online, endangering their own lives and posing a threat to public health and society as a whole. Beyond vaccines, misinformation can also lead to harmful events such as the U.S. Capitol Riot in January 2021. What can we do to protect our mind from these psychological and digital threats? False information and manipulation is becoming increasingly common as we move deep into the Information Age; we need to familiarize ourselves with psychological tools we can use to combat harmful designs on the internet.
A case study of the Shingwauk Residential Schools Centre: A Survivor-centred toolkit for reconciliation
Authors: Reimer Jillie
Published: March 2022

This case study analyzes the programming initiatives of the Shingwauk Residential Schools Centre (SRSC) with the aim to produce an actionable toolkit of six distinct principles for institutions in addressing residential school history and working with Survivors. These six principles—applying Survivor-led, community-first methods; engaging in co-creative and participatory work; re-contextualizing photography through oral history; reclaiming Indigenous objects, spaces, and time; continually re-examining prior reconciliation efforts; and supporting the autonomy of witnessing—all contribute to the ongoing Canadian response to the Truth and Reconciliation Commission of Canada's Calls to Action in confronting systemic racism towards Indigenous peoples, educating the public about residential schools, and advancing the progress of reconciliation efforts. The SRSC’s programming, including the Remember the Children project and the Reclaiming Shingwauk Hall exhibition, along with the centre’s further statements and initiatives, all highlight best practices in the preservation and programming for former residential school sites. By following the methods realized throughout this case study, other institutions can mindfully and meaningfully co-create Survivor-led spaces and programming that will further reconciliation’s aims—listening, learning, supporting, healing, and restoring.
Nobody Wins: The inequitable certification of archival materials as cultural property by the Canadian Cultural Property Export Review Board
Authors: White Olivia
Published: March 2022

The Canadian Cultural Property Export Review Board (CCPERB) was founded by the Government of Canada in 1977 to establish an idealized framework to value and certify items of significant cultural value. This research explores the CCPERB's time-consuming application process and rigid monetary appraisal criteria to demonstrate how the Board discourages the certification of archival material. Emphasizing the fair market value (FMV) of archives through sales data also places Black, Indigenous, and People of Colour (BIPOC) creators, as well as digital records, at a disadvantage for certification. Reforming CCPERB’s processes requires an open dialogue with archival stakeholders to ensure the equitable certification of all forms of cultural property in Canada.
MODEL KOMPOSISI MUSIK TERAPI RELAKSASI UNTUK IBU HAMIL BERBASIS IDIOM MUSIKAL KARAWITAN
Authors: Setiaji Denis
Published: March 2022

ABSTRAK Penelitian ini mencoba untuk melakukan formulasi dalam menciptakan musik yang dapat dijadikan sarana terapi untuk menekan tingkat kecemasan serta memberikan rasa tenang dan nyaman terhadap pendengarnya khususnya ibu hamil. Target jangka panjang dari riset ini ialah bagaimana dampak dari musik terhadap psikologi ibu hamil diharapkan mampu memberikan efek positif terhadap ibu maupun janin yang sedang dikandung. Target jangka pendek yang dihasilkan dari riset dalam proposal berikut yakni mencoba melakukan analalisis kompositoris dan mencermati kaidah-kaidah musik terapi yang dikombinasikan dengan idiom musikal karawitan, dalam hal ini karawitan Jawa, Sunda, dan Bali. Pada akhirnya diharapkan dapat menghasilkan sebuah embrio dari model penciptaan musik terapi berbasis idiom musikal karawitan. Riset ini kemudian mencoba mengeksplorasi bunyi- bunyian lokal untuk dapat diolah kembali menjadi produk yang maslahat untuk masyarakat.Kata kunci: musik, terapi, karawitan, komposisi ABSTRACTThis study tries to formulate music that can be used as a therapy tool to reduce anxiety and provide a sense of calm and comfort to the listeners, especially pregnant women. The long-term target of this research is how the impact of music on the psychology of pregnant women is expected to have a positive effect on both the mother and the fetus being conceived. The short-term target resulting from the research in the following proposal is to try to do a compositorist analysis and observe the rules of therapeutic music combined with karawitan musical idioms, namely Javanese, Sundanese, and Balinese karawitan. Finally, it is hoped that it will produce an embryo of a therapeutic music model based on the musical idiom of karawitan. This research, then, tries to explore local sounds in order to be reprocessed into beneficial products for the community.Keywords: music, therapy, karawitan, composition
TREN ECO-FASHION DENGAN KAIN TENUN GEDOG TUBAN DALAM FASHION FOTOGRAFI CAMPAIGN
Authors: Firdaus Nina , Purnama Pongky Adhi , Candrastuti Ratih
Published: March 2022

Currently eco-friendly trends among Indonesians are in great demand, eco-fashion is one example of the application of eco-friendly trends to maintain the environment by reducing textile waste. However, not many people know about eco-fashion trends. In the making of this Final Task the author will create a fashion campaign photo work, the strength in fashion photography itself is to be able to record images and communicate certain beauty and is expected to be able tokanlkan eco-fashion trends to the public at large. In this fashion campaign photo, the author takes the concept of Ayu Lan Praseja. Ayu Lan Praseja is taken from javanese language which has a beautiful and simple meaning. Ayu Lan Praseja’s concept tells about the nature and behavior of Javanese people inspired by javanese philosophy of “nrima ing pandum” which means to “take for granted whatever happens as God’s will or destiny”. The use of basic photography techniques is used in this Final Task and the result obtained by the author in this Final Task work is Fashion Campaign Photography that can convey the message that the author wants to convey, namely about Ayu Lan Praseja, with a mature concept and also good photo-taking techniques. Keywords: Eco-Fashion, Weaving Gedog Tuban, Fashion Photography.
HAND-COLOURING PADA MULTIPLE EXPOSURE PHOTOGRAM
Authors: Astiti Anin
Published: March 2022

Abstrak Teknik hand-colouring merupakan sebuah teknik pewarnaan pada permukaan kertas foto yang dilakukan secara manual. Hand- colouring merupakan pewarnaan yang sudah dilakukan sejak sebelum ada fotografi warna, yang berguna untuk memberikan efek atau dramatisasi pada sebuah foto. Dari sisi metode, material pewarnanya serta pengetahuan pewarnaannya, teknik hand-colouring secara manual manjadi hal yang lebih menarik bila dibicarakan melalui konteks seni dan berkesenian, terlebih teknik tersebut telah lama digantikan oleh teknik pewarnaan secara digital.Berdasarkan uraian di atas, dapat dikatakan bahwa penulis akan menampilkan kembali teknik hand-colouring yang dilakukan secara manual menggunakan alat pewarna dan memiliki efek warna khas dan menjadi sesuatu yang unik dan menarik bila dimunculkan di masa kini, di mana kesan masa lalu menjadi kekuatan utama pada tampilan visual nantinya. Hand-colouring dalam penelitian kali ini akan dimunculkan pada karya multiple exposure photogram yang juga memiliki nilai estetis dan esensi fotografi yang sesungguhnya.Multiple exposure dalam karya photogram, menjadi teknik sajian dalam menampilkan imaji foto, yang merupakan sebuah teknik yang menjadi fokus penulis sejak tahun 2016. Dengan segala kerumitan dan kesulitan yang sering dihadapai saat mencipta karya, ditemukan photogram memiliki potensi besar untuk dapat dieksplorasi lebih dalam lagi. Perlu diketahui bahwa photogram merupakan sebuah teknik eksplorasi yang dilakukan di kamar gelap, yang membutuhkan kesabaran, ketelatenan di samping pengetahuan teknis secara mendasar yang harus dikuasai. Photogram tidak hanya berkaitan dengan bayangan yang dihasilkan, namun juga berkaitan dengan bagaimana teknik tersebut dapat dieksplorasi dan dilakukan eksperimentasi yang pada akhirnya akan memperkaya dan memperkuat penguasaan teknik yang sudah penulis miliki hingga saat ini.Kata kunci: hand-colouring, photogram, multiple exposure
Analisis Semiotik Roland Barthes Pada Iklan Televisi Pertamina Edisi Ramadan 1442 H
Authors: Wicaksono Arif Ranu , Diyah Fitriyani Afiati Handayu
Published: March 2022

Iklan televisi masih menjadi salah satu media paling efektif untuk mempromosikan produk, mengkampanyekan program dan lain sebagainya. Promosi yang dilakukan perusahaan biasanya melibatkan banyak media baik media offline maupun onlineserta menggunakan berbagai cara seperti persuasif terang-terangan maupun dengan terselubung sehingga iklan yang ditampilkan bebas dilihat oleh para pemirsa sesuai visualisasi yang ditangkap dan berdasarkan pengalamannya masing-masing. Tujuan menayangkan iklan biasanya adalah mempromosikan produk atau bertujuan untuk meningkatkan citra sebuah perusahaan. Pada penelitian ini penulis mencoba membedah iklan televisi Pertamina Edisi Ramadhan 1442 H menggunakan metode penelitian kualitatif melalui teknik analisis semiotika Roland Barthes. Pengumpulan data melalui observasi dan dokumentasi iklan video pertamina pada bulan April - Mei 2021. Hasil penelitian menunjukkan bahwa iklan televisi Pertamina Edisi Ramadhan 1442 H memiliki dua tujuan yaitu mempromosikan produk terbaru dan meningkatkan citra perusahaan.
OPTIMALISASI DESAIN RESTROOM PADA BANGUNAN PUBLIK DI SURAKARTA
Authors: Purnomo Agung , Indarto Indarto
Published: March 2022

Abstract Restroom is as a supporting facility in a public building functioning to be a room for such activities as washing hand, washing face, urinating, and defecating. This room is equipped with a variety of toilet sets including washtafel (was basin), and some forms of closet, bidet and urinoir and other room facilities such as tissue paper and rubbish basket. Surakarta as a cultural, business, and trading business have many public buildings. Attention should be paid to how those buildings can have supporting facilities such as restroom with good sanitation, comfortable, and cultured as the form of good public service to children, adult, and disabled. This applied research aims to answer the problem related to the function of sanitation and restroom form existing in Surakarta and to give design-related solution based on field and literature data. The research procedure included identification, design experiment, and design trial. To explore data of artifact, literature, and informant, observation, literature study, interview, and documentation techniques were used. Design experiment was conducted using design approach and confirmed with evocative, educative, psychological, and social-cultural approaches. SWOT analysis model was used to formulate the restroom design. Design trial was conducted through such activities as design realization (experiment product) and its implementation (design implementation), evaluation, design concept perfecting, and recommendation formulation. Keywords: optimization, restroom design, public building, Surakarta
EKSPRESI VISUAL VIRUS KORONA DALAM MOTIF KREASI KARYA KRIYA KAYU
Authors: Prabowo Rahayu Adi , Supriyanto Ari
Published: March 2022

Para a arte social, esta expresión adoita utilizarse como un movemento para explorar as posibilidades que poden facer os artistas para representar a súa existencia e, ao mesmo tempo, crear preocupación pola comunidade. A presenza de obras de arte non se limita á arte só en aras da arte, senón que se pode utilizar como un medio de comunicación máis amplo, mesmo máis alá dos límites do diálogo verbal. Varias condicións sociais da sociedade poden ser dirixidas a ser comunicadas, comprometidas e colaboradas na forma de arte. O brote do virus corona, como unha condición que cambia moito o estilo de vida das persoas, é un evento ao que poden responder as formas de arte creativas e innovadoras. A arte tradicional que ten un profundo significado filosófico-simbólico cómpre mostrar nos matices das mensaxes e das esperanzas para a comunidade. A presenza da arte tradicional en forma de novos patróns dará unha profunda impresión para que poida presentar un discurso sobre o desenvolvemento de obras posteriores. Este traballo de investigación é unha das respostas ao propósito de desenvolver este traballo. Este estudo utiliza un método de exploración de motivos na creación de obras de arte artesanal, é dicir, traer novos motivos a partir dunha combinación de motivos tradicionais e obxectos do virus da corona en forma de creacións de obras de arte tradicionais. Esta obra está empaquetada cunha exposición de técnicas de talla en semirelevo aplicando un novo patrón de motivos cultivados de acordo co ámbito das técnicas de talla en madeira. Este método derrama motivos e imaxes tradicionais do virus da corona nun estilo tridimensional con tamaños proporcionais como un esforzo para aumentar a comprensión pública da artesanía cunha nova aparencia.Palabras clave: Corona Virus, Motivo Tradicional, Talla en madeira
Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets
Authors: Wolf Robert , Grammbauer Sophie , Palankar Raghavendra , Tolksdorf Céline , Moritz Eileen , Böhm Andreas , Hasan Mahmoud , Hafkemeyer Annika , Greinacher Andreas , Tzvetkov Mladen V. , Rauch Bernhard H. , Jedlitschky Gabriele
Published: March 2022

The multidrug resistance protein 4 (MRP4) is highly expressed in platelets and several lines of evidence point to an impact on platelet function. MRP4 represents a transporter for cyclic nucleotides as well as for certain lipid mediators. The aim of the present study was to comprehensively characterize the effect of a short-time specific pharmacological inhibition of MRP4 on signaling pathways in platelets. Transport assays in isolated membrane vesicles showed a concentrationdependent inhibition of MRP4-mediated transport of cyclic nucleotides, thromboxane (Tx)B2 and fluorescein (FITC)- labeled sphingosine-1-phosphate (S1P) by the selective MRP4 inhibitor Ceefourin-1. In ex vivo aggregometry studies in human platelets, Ceefourin-1 significantly inhibited platelet aggregation by about 30-50% when ADP or collagen was used as activating agents, respectively. Ceefourin-1 significantly lowered the ADP-induced activation of integrin aIIbb3, indicated by binding of FITC-fibrinogen (about 50% reduction at 50 mM Ceefourin-1), and reduced calcium influx. Furthermore, pre-incubation with Ceefourin-1 significantly increased PGE1- and cinaciguat-induced vasodilatorstimulated phosphoprotein (VASP) phosphorylation, indicating increased cytosolic cAMP as well as cGMP concentrations, respectively. The release of TxB2 from activated human platelets was also attenuated. Finally, selective MRP4 inhibition significantly reduced both the total area covered by thrombi and the average thrombus size by about 40% in a flow chamber model. In conclusion, selective MRP4 inhibition causes reduced platelet adhesion and thrombus formation under flow conditions. This finding is mechanistically supported by inhibition of integrin aIIbb3 activation, elevated VASP phosphorylation and reduced calcium influx, based on inhibited cyclic nucleotide and thromboxane transport as well as possible further mechanisms.
Papua Separatis Terrorist Groups Detection Through Osint and Counter Intelligence Effort (Osint Detection Study On The Baintelkam Polri Separatist Management Unit)
Authors: Maekel Eugaliel Pindonta Sembiring  , Arthur Josias Simon
Published: March 2022

The Separatist Terrorist Group Movement (KST) is a group that demands independence or secession from Indonesia. Public demand for the police as a public institution that maintains the national security of the Republic of Indonesia is a big responsibility that must be implemented. The Separatist Terrorism Group (KST) movement and researchers will also analyze the role of the National Police's Baintelkam Separatist Countermeasures Unit in collecting OSINT-based information which is then processed into intelligence information, especially in terms of identifying threats that could threaten state sovereignty. The type of research used is qualitative research, the data collection strategy chosen is a qualitative data collection strategy. The results show that the large-scale use of OSINT has created new contexts and perspectives that help intelligence and security services to better understand the complexities of certain security developments in local or national contexts. On the movement of KST, among others. The intelligence community analyzes and collects data from all available open sources to try to find interesting data in the large amount of free information available.
Implementasi Konsep Behaviorally Anchor Rating Scale pada Sistem Informasi Penilaian Kinerja Karyawan Berbasis Web
Authors: Setiawan Ridwan , Cahyana Rinda , Hakim Prayoga
Published: March 2022

Pada area dunia kerja, penilaian kinerja karyawan memiliki peran penting. Hal ini akan berdampak dengan keputusan yang akan diambil oleh perusahaan berkaitan pada kinerja dari karyawannya. Setiap industri mempunyai cara tersendiri dalam menilai kinerja karyawannya, salah satunya terdapat metode penilaian berdasarkan perndekatan terhadap perilaku kerja yaitu Behaviorally Anchor Rating Scale (BARS). Tujuan penelitian ini untuk merancang sistem informasi penilaian kinerja karyawan berbasis platform web yang dapat menyajikan informasi mengenai penilaian kinerja setiap karyawan berdasarkan tugas yang telah dikerjakan dalam setiap bulannya, dan membantu pimpinan perusahaan meninjau perkembangan pekerjaan karyawannya. Metode pengembangan sistem yang digunakan dalam penelitian ini adalah Rational Unified Process (RUP) hanya melakukan tahapan Inception, Elaboration, dan Construction dengan pemodelan Unified Modelling Language (UML) serta pengujian Alpha dengan menggunakan metode black-box testing. Hasil pada penelitian ini dapat menerapkan konsep Behaviorally Anchor Rating Scale (BARS) terhadap sistem informasi penilaian kinerja karyawan berbasis web dengan beberapa hak akses multi user diantaranya admin, koordinator, dan karyawan. Sistem informasi hanya melakukan penambahan data indikator penilaian berdasarkan konsep BARS, pengelolaan tugas, sekaligus melihat perkembangan pekerjaan, serta melakukan penilaian oleh koordinator setelah pekerjaan diselesaikan oleh karyawan.
Pengaruh Self Efficacy terhadap Pengambilan Keputusan karir peserta didik pada SMKN 3 Kota Bima
Authors: Amin Nur Syariful , Muhamadiah Muhamadiah , Sarbudin Sarbudin
Published: March 2022

Dalam pengambilan keputusan karir yang tepat tentunya harus disesuaikan dengan kemampuan yang dimiliki peserta didik itu sendiri. Selain itu, ada beberapa hal yang sangat mempengaruhi proses pengambilan keputusan karir itu sendiri, seperti faktor sosial ekonomi keluarga, pengaruh orangtua, teman sebaya. Selain dipengaruhi oleh faktor eksternal, faktor internal juga sangat mempengaruhi, seperti kesadaran diri, minat, serta keyakinan. Salah satu yang dapat mempengaruhi pengambilan keputusan karir peserta didik dalam faktor individu yaitu self efficacy. Tujuan dari penelitian ini adalah untuk mengetahui apakah ada pengaruh self Efficacy terhadap pengambilan keputusan karir peserta didik dan untuk mengetahui seberapa besar pengaruh self Efficacy terhadap pengambilan keputusan karir peserta didik. Pendekatan penelitian ini dengan deskriptif kuantitatif dengan jenis penelitian kuantitatif. Teknik pengumpulan data dilakukan dengan obsevasi, angket, dan dokumentasi. Analisis data dilakukan dengan menggunakan rumus Regresi Linear. Berdasarkan paparan data dan hasil penelitian, dapat ditarik kesimpulan : Dari hasil perhitungan secara statistik diperoleh nilai r hitung sebesar = 49.022. Hasil perhitungan dengan menggunakan rumus regresi linear dikatakan tidak menyimpang bila koefesien korelasi yang dihasilkan dari perhitungan regresi linear lebih dari r tabel yaitu 7.657. Karena nilai r hitung lebih besar dari r tabel maka hipotesis nol (Ho) ditolak dan menerima hipotesis alternatif (Ha) yaitu ada pengaruh signifikan antara self Efficacy terhadap pengambilan keputusan karir peserta didik pada SMKN 3 Kota Bima tahun pelajaran 2020/2021 baik pada taraf signifikasi 5%= r hitung > r tabel = >7. 657. Jadi hasil perhitungan dapat dikatakan bahwa self Efficacy terhadap pengambilan keputusan karir peserta didik, sesuai dengan hasil perhitungan dengan menggunakan rumus regresi linear diperoleh r hitung 94,022, sehingga dapat disimpulkan bahwa self efficacy sebagai variabel X dan pengambilan keputusan karir sebagai variabel Y.Pengaruh
PLATFORM INTERAKTIF BERBASIS WEB UNTUK PEMBELAJARAN DESAIN ANTARMUKA PENGGUNA (UI) APLIKASI ANDROID DENGAN FUNGSI VALIDASI OTOMATIS
Authors: Syaifudin Yan Watequlis , Ruslan Muhammad Sofiul Fuad , Ariyanto Rudy , Ardyningrum Nabilah Argyanti
Published: March 2022

Seiring meningkatnya popularitas perangkat pintar Android, permintaan programmer aplikasi Android telah meningkat pesat. Atas dasar fakta ini, pemrograman aplikasi Android telah menjadi salah satu mata pelajaran paling populer di program studi Teknologi Informasi. Dalam aplikasi Android, antarmuka pengguna memiliki peran penting untuk membuat aplikasi menjadi interaktif agar pengguna dapat nyaman menggunakan aplikasi Android. Berdasarkan studi sebelumnya, Android Programming Learning Assistance System (APLAS) yang telah digunakan sebagai platform pembelajaran mandiri untuk pembelajaran pemrograman Android. Dalam makalah ini, kami mengusulkan platform pembelajaran mandiri berbasis web di APLAS untuk mempelajari cara membuat desain antarmuka pengguna secara interaktif menggunakan kode XML.  Materi pembelajaran terdiri dari 15 topik yang mencakup pembelajaran tata letak dan penggunaan resource untuk antarmuka aplikasi. Mahasiswa akan mendapatkan tugas dalam dokumen panduan yang harus diselesaikan pada setiap topik, kemudian jawaban mahasiswa tersebut dapat divalidasi secara otomatis di server dan dan web APLAS akan menampilkan hasil validasi, yaitu berupa PASSED dan FAILED. Untuk mengevaluasi efektivitas dari platform APLAS ini, kami meminta 40 mahasiswa di program studi Teknologi Informasi di Indonesia untuk menyelesaikan semua topik pembelajaran pemrograman Android yang diberikan pada web. Hasil pengujian menunjukkan bahwa semua mahasiswa menyelesaikan tugas dengan benar dan memberi komentar positif pada nilai mereka, yang mengkonfirmasi keefektifan sistem APLAS.
Mulheres e feminismo: história e desafios
Authors: Ferrazza Daniele de Andrade , Leite Hilusca Alves
Published: March 2022

O livro Mulheres e feminismo: história e desafios se propõe a apresentar, nas diferentes perspectivas adotadas pelas diversas autoras, discussões sobre as movimentações feministas de suas trajetórias históricas aos debates contemporâneos. Pretende, também, sensibilizar e mobilizar mulheres em diferentes contextos para uma única luta relacionada aos enfrentamentos contra relações patriarcais, machistas e falocêntricas que reproduzem violências de gênero e impedem a igualdade de direitos de mulheres na contemporaneidade brasileira (RAGO; PELEGRINI, 2019). A coletânea de textos, fruto de um trabalho tecido a várias mãos, é composta por sete capítulos. O primeiro capítulo, escrito por Bárbara Cossettin Costa Beber Brunini, é uma carta-convite a aventurar-se pelos debates feministas, no reconhecimento da potência das narrativas na interseccionalidade decolonial. No segundo capítulo, Daniele de Andrade Ferrazza propõe uma análise da constituição e enfrentamento dos processos de normalização do corpo da mulher. No terceiro capítulo, Bianca Valoski recorre ao feminismo marxista para tratar da acumulação originária sobre corpos femininos explorados no trabalho produtivo e reprodutivo. Seguindo a linha de discussão na perspectiva marxista, Nataly Batista de Jesus explora, no quarto capítulo, o papel das mulheres russas no período pré-revolucionário para compreender o processo de emancipação e conquistas de direitos das mulheres revolucionárias. Pautadas no materialismo histórico de constituição e desenvolvimento desujeitos, expresso pela Psicologia Histórico-Cultural, Tamires Lombardi Mezzon e Hilusca Alves Leite abordam a noção de saúde/doença do corpo feminino. No sexto capítulo, Daniele de Andrade Ferrazza e Mariana Frediani Sant’Ana analisam o fenômeno de psiquiatrização do corpo feminino em sua constituição histórica e atual. E, finalmente, no sétimo capítulo, Débora Nicolau de Oliveira e Deborah Karolina Perez discutem como as revistas brasileiras Manequim, Vogue Brasil e Marie Claire construíram representações sociais da mulher brasileira e influenciaram as mulheres no século XXI. Esperamos, com a proposta de coletânea que aqui apresentamos, somar forças a outras produções acadêmicas sobre os estudos feministas e influenciar reflexões entre leitoras e leitores dispostos a compor conosco a constituição de enfrentamentos ao massacre de direitos que vivenciamos nestes tempos sombrios. Momento no qual forças de direita e ultradireita, não só no Brasil, mas em outros países no mundo, atrasam debates favoráveis à elaboração e implementação de políticas pela garantia da igualdade de gênero. Enfim, organizar este livro significa rememorar lutas históricas feministas e acreditar na tessitura de novos horizontes mais justo, igualitário e libertário.
Hypersensitivity to Gadolinium-Based Contrast Media
Authors: Gracia Bara M. Teresa , Gallardo-Higueras Alicia , Moreno Esther M. , Laffond Elena , Muñoz Bellido Francisco J. , Martin Cristina , Sobrino Miriam , Macias Eva , Arriba-Méndez Sonia , Castillo Rosita , Davila Ignacio
Published: March 2022

Gadolinium-based contrast agents (GBCAs) are frequently used in magnetic resonance imaging (MRI) examinations to increase sensitivity in diagnoses. Recently, an increase in the description of hypersensitivity reactions to GBCAs has been detected. We performed research in PubMed, PubMed, SCOPUS, and EMBASE until September 2021, searching for studies regarding immediate and delayed hypersensitivity reactions to gadolinium-based contrast agents in which an allergy study was performed. The initial research identified 149 articles written in English. After excluding articles duplicated and articles that had irrelevant designs, 26 articles were included. Finally, 17 studies concerning immediate reactions, six studies concerning non-immediate reactions, and three concerning both that performed allergy evaluations were selected. In the review, we analyzed the characteristics of immediate and delayed reactions and the results of the allergy study and cross-reactivity. Skin tests seem to have acceptable accuracy, but drug provocation tests are still needed when skin tests are negative o to find alternative agents. Although cross-reactivity patterns are not well established, cross-reactivity seems to exist among macrocyclic agents. Notwithstanding, the number of patients analyzed is low and further studies are required. A management algorithm is suggested.
Overview of SERPING1 Variations Identified in Hungarian Patients With Hereditary Angioedema
Authors: Szabó Edina , Csuka Dorottya , Andrási Noémi , Varga Lilian , Farkas Henriette , Szilágyi Ágnes
Published: March 2022

Background

Hereditary angioedema (HAE) due to C1-inhibitor (C1-INH) deficiency (C1-INH-HAE) is a rare autosomal dominant disorder, characterized by recurrent, unpredictable edematous symptoms involving subcutaneous, and/or submucosal tissue. C1-INH-HAE may be caused by more than 700 different mutations in the gene encoding C1-INH (SERPING1) that may lead to decreased protein synthesis or to functional deficiency.

Methods

Concentrations of C1-INH, C4, C1q, and anti-C1-INH antibodies, as well as functional C1-INH activity were determined in subjects suffering from edematous symptoms and admitted to the Hungarian Angioedema Center of Reference and Excellence. In those patients, who were diagnosed with C1-INH-HAE based on the complement measurements, SERPING1 was screened by bidirectional sequencing following PCR amplification and multiplex ligation-dependent probe amplification. For detecting large deletions, long-range PCRs covering the entire SERPING1 gene by targeting 2–7 kb long regions were applied.

Results

Altogether 197 individuals with C1-INH deficiency belonging to 68 families were identified. By applying Sanger sequencing or copy number determination of SERPING1 exons, 48 different mutations were detected in 66/68 families: 5 large and 15 small insertions/deletions/delins, 16 missense, 6 nonsense, and 6 intronic splice site mutations. Two novel variations (p.Tyr199Ser [c.596A>C] and the duplication of exon 7) were shown to cosegregate with deficient C1-inhibitor level and activity, while two other variations were detected in single patients (c.797_800delinsCTTGGAGCTCAAGAACTTGGAGCT and c.812dup). A series of long PCRs was applied in the remaining 2 families without an identified mutation and a new, 2606 bp long deletion including the last 91 bp of exon 6 (c.939_1029+2515del) was identified in all affected members of one pedigree. In the remaining one family, a deep intronic SERPING1 variation (c.1029+384A>G) was detected by a targeted next-generation sequencing panel as reported previously.

Conclusions

Sequencing and copy number determination of SERPING1 exons uncover most pathogenic variants in C1-INH-HAE patients, and further methods are worth to be applied in cases with unrevealed genetic background. Since knowledge of the genetic background may support the establishment of the correct and early diagnosis of C1-INH-HAE, identification of causative mutations and reporting data supporting the interpretation on the pathogenicity of these variants is of utmost importance.
Application of 3D Hepatic Plate-Like Liver Model for Statin-Induced Hepatotoxicity Evaluation
Authors: Xu Jiecheng , Pan Daogang , Liao Wei , Jia Zhidong , Pan Mingxin , Weng Jun , Han Xu , Li Shao , Li Yang , Liang Kangyan , Zhou Shuqin , Peng Qing , Gao Yi
Published: March 2022

Background: Drug-induced liver injury is one of the main reasons of withdrawals of drugs in postmarketing stages. However, an experimental model(s) which can accurately recapitulates liver functions and reflects the level of drug hepatotoxicity is lack. In this study, we assessed drug hepatotoxicity using a novel three-dimensional hepatic plate-like hydrogel fiber (3D-P) co-culture system.

Methods: During the 28-days culture period, the liver-specific functions, hepatocyte polarity, sensitivity of drug-induced toxicity of 3D-P co-culture system were evaluated with 2D co-culture, collagen sandwich co-culture, 3D hybrid hydrogel fiber co-culture and human primary hepatocytes as controls. High-content imaging and analysis (HCA) methods were used to explore the hepatotoxicity mechanism of five statins.

Results: The 3D-P co-culture system showed enhancing liver-specific functions, cytochrome P450 enzymes (CYPs) metabolic activity and bile excretion, which were considered to result from improved hepatocyte polarity. Three of the statins may cause acute or chronic hepatotoxicity by via different mechanisms, such as cholestatic liver injury.

Conclusion: Our 3D-P co-culture system is characterized by its biomimetic hepatic plate-like structure, long-term stable liver specificity, and prominent bile secretion function, making it applicable for acute/chronic drug hepatotoxicity assessments.