bluuebunny/crossref_metadata_2025 huggingface dataset:
Protective effects of honey by bees (Apis dorsata) on decreased cortical thickness and bone impact strength of ovariohysterectomized rats as models for menopause
Authors: Yudaniayanti Ira Sari , Primarizky Hardany , Nangoi Lianny , Yuliani Gandul Atik
Published: June 2019

Aim: This study aimed to determine the potential of honey as anti-osteoporosis by evaluating its effectiveness in increasing bone impact strength and cortical thickness, through scanning electron microscopy (SEM) examination. Materials and Methods: Forty-five female rats at 3 months of age, weighing 150-200 g were used in the study. They were placed in individual cages and adapted to food and environment for 10 days. On the 11th day, after the animals were adapted for 10 days, the animals were randomly divided into five treatment groups (n=9): Sham operation group (SH); ovariohysterectomized (OVX) group with no treatment; OVX with treatment Apis dorsata 1 g/kg BW (AD-1); OVX with treatment A. dorsata 2 g/kg BW (AD-2); and OVX with treatment A. dorsata 4 g/kg BW (AD-3). Furthermore, those nine rats in each treatment group were divided into three groups. Three of them were observed at months 1st, 2nd, and 3rd so that in each observation taken three rats in each treatment group. At the end of the study, the rats were euthanized and necropsy for taking their second femoral bone, i.e. dexter region for examining their bone impact strength, while the sinister region was used for measure the cortical thickness of the femoral diaphysis and examining their bone microarchitecture using SEM analysis. Results: Based on results of the ANOVA test, the cortical thickness measurements of femoral diaphyseal can be seen that from month 1 to month 3 the lowest result was found in the group of rats that were OVX-I. Meanwhile, the highest result was found in the group of rats that were not OVX (SH-III). It was significantly different from the other treatment groups (p<0.05). The groups of rats were OVX with honey supplementation at doses of 2 g/kg BW had shown an increasing pattern in the cortical bone thickness from month 1 to month 3. Even on the observation of the 3rd month, the cortical bone thickness in the AD-2 (AD-2-III) group was not significantly different (p>0.05) from that in the group of rats was not OVX in month 1 (SH-I). The results of the bone impact strength measurement from month 1 to month 3 indicated that the groups of rats were OVX without the administration of honey supplements had the lowest value. The highest bone impact strength was found in the group of rats that was not OVX, but not significantly different (p>0.05) with the groups of rats that were OVX administered honey supplement with a dose of 2 g/kg BW (AD-2) and 4 g/kg BW (AD-3). Conclusion: The supplement of honey A. dorsata at doses of 2 g/kg BW in the group of rats was that OVX can inhibit the decreasing of the cortical bone thickness and repair damage in microarchitecture to generate bone impact strength. As a result, bones are not easily broken.
Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus
Authors: Goodarzi Mark O. , Nagpal Tanvi , Greer Phil , Cui Jinrui , Chen Yii-Der I. , Guo Xiuqing , Pankow James S. , Rotter Jerome I. , Alkaade Samer , Amann Stephen T. , Baillie John , Banks Peter A. , Brand Randall E. , Conwell Darwin L. , Cote Gregory A. , Forsmark Christopher E. , Gardner Timothy B. , Gelrud Andres , Guda Nalini , LaRusch Jessica , Lewis Michele D. , Money Mary E. , Muniraj Thiruvengadam , Papachristou Georgios I. , Romagnuolo Joseph , Sandhu Bimaljit S. , Sherman Stuart , Singh Vikesh K. , Wilcox C. Mel , Pandol Stephen J. , Park Walter G. , Andersen Dana K. , Bellin Melena D. , Hart Phil A. , Yadav Dhiraj , Whitcomb David C. ,   on behalf of the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC)
Published: June 2019

Introduction:

Diabetes mellitus (DM) is a complication of chronic pancreatitis (CP). Whether pancreatogenic diabetes associated with CP-DM represents a discrete pathophysiologic entity from type 2 DM (T2DM) remains uncertain. Addressing this question is needed for development of specific measures to manage CP-DM. We approached this question from a unique standpoint, hypothesizing that if CP-DM and T2DM are separate disorders, they should be genetically distinct. To test this hypothesis, we sought to determine whether a genetic risk score (GRS) based on validated single nucleotide polymorphisms for T2DM could distinguish between groups with CP-DM and T2DM.

Methods:

We used 60 T2DM single nucleotide polymorphisms to construct a weighted GRS in 1,613 subjects from the North American Pancreatitis Study 2 and 2,685 subjects from the Multi-Ethnic Study of Atherosclerosis, all of European origin.

Results:

The mean GRS was identical between 321 subjects with CP-DM and 423 subjects with T2DM (66.53 vs 66.42,P= 0.95), and the GRS of both diabetic groups was significantly higher than that of nondiabetic controls (n = 3,554,P< 0.0001). Exploratory analyses attempting to enrich the CP-DM group for pancreatogenic diabetes, such as eliminating diabetes diagnosed before CP, requiring pancreas-specific comorbidities, or removing those with a family history of diabetes, did not improve the ability of the GRS to distinguish between CP-DM and T2DM.

Discussion:

Recognizing that we lacked a gold standard to define CP-DM, our study suggests that CP-DM may be a subtype of T2DM, a notion that should be tested in future, large prospective studies.
On the order sequence of an embedding of the Ree curve
Authors: Skabelund Dane C.
Published: June 2019

In this paper we compute the Weierstrass order-sequence associated with a certain linear series on the Deligne–Lusztig curve of Ree type. As a result, we show that the set of Weierstrass points of this linear series consists entirely of 𝔽
q
-rational points.
Using the hemoglobin-binding Staphylococcus aureus protein IsdH to enable plasma analysis of hemolyzed blood samples
Authors: Sæderup Kirstine Lindhardt , Revsholm Jesper , Richardt Patrick Bjork , Christiansen Stig Hill , Hennig Dorle , Moestrup Søren Kragh , Graversen Jonas Heilskov
Published: June 2019

Background

Intravascular hemolysis and in vitro hemolysis are prevalent contributors to failed blood sample analysis in the routine hospital laboratory. Interferences by hemoglobin in spectrophotometric and certain enzyme activity assays is the major causative factor.

Methods

By exploiting the hemoglobin-binding properties of the iron-regulated surface determinant H (IsdH) protein from Staphylococcus aureus we have developed a new method to instantly remove hemoglobin and hemoglobin-haptoglobin complexes from plasma in vitro thereby enabling the measurement of hemoglobin-sensitive analytes in hemolyzed plasma. In the present study we used an engineered IsdH mutant form conjugated to Sepharose for the efficient removal of plasma hemoglobin in concentrations up to 15 mg/mL. The high abundance of haptoglobin, which forms a tight complex with hemoglobin in plasma, did not affect the hemoglobin removal by IsdH Sepharose.

Results

Applying the method on plasma samples that beforehand were spiked with blood hemolysate re-enabled measurement of the hemolysis sensitive parameters: alkaline phosphatase, conjugated bilirubin, iron, ferritin, γ-glutamyltransferase, total thyroxine and troponin T. IsdH Sepharose-mediated hemoglobin removal also enabled measurement of hemolysis sensitive parameters in hemolyzed samples from anonymized patients.

Conclusions

In conclusion, IsdH Sepharose is a simple cost-effective pretreatment of hemolyzed samples correcting and enabling the measurement of several important hemoglobin-sensitive parameters in a way compatible with standard procedures in routine laboratories.
Repairs and old-age categorisations: interactional and categorisation analysis
Authors: Charalambidou Anna
Published: June 2019

This paper examines the use of self-repairs in ascribing old-age categorisations to self and others in casual interactions among friends. Membership categorisation analysis and conversation analysis are employed to analyse self-recorded, everyday conversations of a group of older Greek Cypriot women with a long interactional history. The interactional organisation of old-age labels, and specifically instances of self-repair of age categorisations, reveal that members orient to old-age categories as hierarchically positioned and inference-rich. Members make relevant a very intricate set of expectations of who can be categorised by whom, with what specific age category term and at which context, partly because other-categorisations can also implicate one’s self-categorisation as old. Sequential and categorisation analyses provide a powerful analytical toolkit for the investigation of participants’ local system of self- and other-ascription of explicit -but also implicit- age identities. It is shown that the combination of membership categorisation analysis and conversation analysis can be extended beyond the analysis of turn-generating categories and can be instrumental in analysing flexible, context-shaped and agentively managed category identifications that also have currency beyond the local interactional occasion.
Agency and epistemic authority in question-answer sequences between art museum guides and visitors diagnosed with dementia
Authors: Isaac Adrienne R. , Hamilton Heidi E.
Published: June 2019

Recent studies documenting the real-time details of human interactions have revealed the way in which artefacts in the immediate physical surround facilitate the display and demonstration of knowledge. The museum setting in which physically present objects prompt and support visitor displays of knowledge is particularly well-suited for individuals managing symptoms related to memory loss as a result of dementia, especially of the Alzheimer’s type. In this paper, we explore question-answer sequences taken from three hour-long guided sessions within an art gallery program involving museum guides who were specially trained to work with visitors with dementia. We investigate representative sequences 1) in which visitors exercise interactional control by posing questions to guides that relate to the visitors’owninterests and 2) in which guides pose questions to visitors regarding topics that relate to the visitors’ personal lives. We argue that these two discursive practices promote interactional meaningfulness, in that the former pattern affords the visitors interactional agency, while the latter pattern allows them to display their epistemic authority. Finally, we consider how insights from this therapeutic model may be translated from the museum to the home setting.
Indications and outcomes of splenectomy for hematological disorders
Authors: Ciftciler Rafiye , Pasayeva Aysel , Aksu Salih , Ozcebe Osman , Sayınalp Nilgun , Malkan Umit Yavuz , Buyukasık Yahya , Haznedaroglu Ibrahim C.
Published: June 2019

Background and Aim

Splenectomy is a frequent component of the diagnosis and treatment of hematological disorders. The aim of this study was to define the indications and outcomes of splenectomy for benign and malign hematological disorders.

Materials and Methods

One hundred and two patients with hematological disease who had splenectomy at Hacettepe University Hospital between the years of 2010 and 2018 were evaluated.

Results

A total of one hundred and two patients were included in this study. The median age was 52 (20-82) years at the time of splenectomy. Most of the patients were female (57.9%). The median follow up time was 11.0 (0.03-87.9) months after splenectomy. Splenectomy was performed to diagnose thirty patients (29.4%). Seventy-two patients underwent splenectomy for the treatment of hematological disease (70.6%). Twenty-seven patients (90%) were diagnosed with various lymphomas. Two patients (6.7%) were diagnosed with hairy cell leukemia and one patient (3.3%) was diagnosed with large granular lymphocytic leukemia.

Conclusion

In conclusion, an improvement in medical therapy, especially with monoclonal antibodies, the indications and outcomes of splenectomy for hematologic disorders have changed extremely in last years. Nevertheless, splenectomy has an important role for diagnosis and treatment of benign and malign hematological disorders.
Investigations into the mechanisms of electrohydrodynamic instability in free surface electrospinning
Authors: Jiang Guojun , Johnson Lee , Xie Sheng
Published: June 2019

Free surface electrospinning is a continuous electrospinning method for low-cost, massive production of nanofibers. The interjet distanceλis a critical parameter in free surface electrospinning, which directly determines the nanofiber production efficiency. In this investigation, we studied the interjet distance during free surface electrospinning based on electrohydrodynamic instability theoretically and experimentally, with special interest focused on the effect of surface tension and electric field intensity on the interjet distance. The experimental results indicated that the critical parameters affecting the interjet distance were the surface tension and applied voltage, which was in good compliance with the theoretical prediction. The relationship between interjet distanceλand surface tension followed an allometric law with positive exponential function, and the relationship between interjet distanceλand applied voltage followed an allometric law with negative exponential function. The present results can be used to understand the basic parameters which determine the interjet distance in free surface electrospinning.
Gendergerechte Bewegungsförderung bei älteren Männern
Authors: Tittlbach Susanne , Strobl Helmut
Published: June 2019

Männer verzeichnen im Vergleich zu Frauen einen stärkeren Rückgang an Bewegung im Alter und stellen eine vulnerable Zielgruppe der Bewegungsförderung dar. Von bestehenden Bewegungsangeboten werden ältere Männer oft nicht gut erreicht. Erfolgreiche Angebote für ältere Männer müssen daher genderorientiert sein, d.h. gesellschaftlich geprägte Vorstellungen über Männlichkeit aufgreifen, diese aber mit gesundheitlichen Praktiken und einem im Alter verminderten Fitness-Zustand in Einklang bringen.
Geschlechts- und genderspezifische Aspekte der Arzneimittelversorgung
Authors: Glaeske Gerd
Published: June 2019

In der Arzneimittelversorgung zeigen sich seit vielen Jahren relativ konstant Unterschiede in der geschlechtsspezifischen Verteilung bestimmter Medikamentengruppen. Auffällig ist zum Beispiel die eher leitliniengerechte Verordnung von Arzneimitteln in der Sekundärprävention von Koronarer Herzkrankheit für Männer und die vergleichsweise häufigere Verordnung von Psychopharmaka für Frauen, die oftmals nicht mit den Empfehlungen zur Vermeidung einer inadäquaten Medikation für ältere Menschen übereinstimmt.
Muslim doctors in Catholic hospitals: a challenge for the Christian profile?
Authors: Arens Thorsten
Published: June 2019

This work won the IGGS Research Award 2018. It was published in 2018 as: "Christliches Profil und muslimisches Personal. Katholische und muslimische Ärzte in Caritas-Krankenhäusern" by Kohlhammer, Stuttgart.

The increased immigration in Germany since 1949 has resulted in around four million Muslims settling there. Some of them are employed by churches, particularly as doctors in Catholic hospitals. At the same time, church leaders are demanding a clear, recognisable Christian profile for these institutions. What does this mean and what are the resulting challenges for the Christian profile with regard to a Muslim workforce? These highly topical and hitherto scientifically unanswered questions have been addressed in a qualitative study, in which the answers of six Catholic and six Muslim physicians with different medical specialisations in different Caritas hospitals are assigned to the categories of the three-level-model of the Christian profile. Among other things, the evaluations lead to the following result: Neither the coexistence of Catholic and Muslim physicians nor the headscarves of Muslim women prove to be a challenge in hospitals. It is rather framework conditions in the healthcare system that create problems and conflict with Christian requirements. One of the final recommendations is therefore that the people responsible for the framework provide conditions in which Catholic and Muslim physicians can credibly fulfil the requirements of the Christian mission. The results of the study also illustrate the necessity for a constant thematisation of the Christian foundation of faith as well as of church employment law. Therefore, physicians are able to understand, support and discuss Christian ideas on norms and morals as well as church framework requirements.
Thiadiazole-2-Thiol-5-Thione and 2,5-Dimercapto-1,3,4-Thiadiazol Tautomerism, Conformational Stability, Vibrational Assignments, Inhibitor Efficiency and Quantum Chemical Calculations
Authors: Esmaiel Muhammad H. , Basuony Hany A. , Al-Nawasany Mohamed K. , Shulkamy Musab M. , Shaaban Ibrahim A. , Abuelela Ahmed M. , Zoghaib Wajdi M. , Mohamed Tarek A.
Published: June 2019

Raman (3700–100 cm−1) and infrared (4000–400 cm−1) spectra of 2,5-Dimercapto-1,3,4-thiadiazol (DMTD) were recorded in the solid phase. Six structures (1–6) were initially proposed for DMTD as a result of thiol-thione tautomerism and internal rotation(s) of thiol group(s) around the C–S bond. Quantum chemical calculations were carried out for an isolated molecule (1–6) using density functional theory (B3LYP) and ab initio MP2(full) methods utilizing 6-31G(d) and 6-311++G(d,p) basis sets which favor thiol-thione tautomerism (structure 4). Relaxed potential energy surface scans of structure 4 revealed an additional conformer (the thiol group is out-of-plane, structure 7) using the aforementioned methods at 6-311++G(d,p) basis set. For additional verification, plane-wave solid state calculations were carried out at PW91 and PBEsol came out in favor of conformer 7. This is in agreement with the computed/observed SH in-plane bending of S-7 (959/941 cm−1) rather than the one estimated at (880 cm−1) for S-4. Moreover, the observed split IR/Raman bands were found consistent with solid state calculated frequencies of S-7 assuming two molecules per unit cell bonded via H-bonding intermolecular interactions. Aided by vibrational frequency calculations, normal coordinate analysis, force constants and potential energy distributions (PEDs), a complete vibrational assignment for the observed IR and Raman bands is proposed herein. Furthermore, we have estimated the frontier molecular orbitals and atomic charges to account for the corrosion inhibition efficiency of DMTD along with its binding sites to the metal surface. Our results are discussed herein and compared to similar molecules whenever appropriate.
Comparative Effects of Game Profile–Based Training and Small-Sided Games on Physical Performance of Elite Young Soccer Players
Authors: Dello Iacono Antonio , Beato Marco , Unnithan Viswanath
Published: June 2019

Dello Iacono, A, Beato, M, and Unnithan, V. Comparative effects of game profile–based training and small-sided games on physical performance of elite young soccer players. J Strength Cond Res 35(10): 2810–2817, 2021—This study was designed to investigate and compare the effects of game profile–based training (GPBT) and small-sided game (SSG) training on physical performances of elite youth soccer players during the in-season period. Twenty young soccer players (18.6 ± 0.6) were randomly assigned to either GPBT or SSG protocols performed twice a week for 8 weeks. The GPBT consisted of 2 sets of 6–10 minutes of intermittent soccer-specific circuits. The SSG training consisted of 3–5 sets of 5 vs. 5 SSGs played on a 42 × 30-m pitch. Before and after the training program, the following physical performances were assessed: repeated sprint ability, change of direction (COD), linear sprinting on 10 m and 20 m, countermovement jump, and intermittent running (YYIRL1). Significant improvements were found in all the assessed variables after both training interventions (p < 0.05). The GPBT group improved more than the SSG group in the 10-m and 20-m sprint tests by 2.4% (g = 0.4; small effect) and 4% (g = 0.9; large effect), respectively. Conversely, the SSG group jumped 4% higher (g = 0.4; small effect) and resulted 6.7% quicker than the GPBT (g = 1.5; large effect) in completing the COD task. These results suggest both GPBT and SSGs to be effective for fitness development among elite young soccer players during the competitive season. More importantly, these 2 conditioning methodologies may be considered in terms of specificity for selectively improving or maintaining specific soccer fitness-related performances in the latter phase of the season.
BDS Suppression Attempts in Germany Backfire
Authors: Hever Shir
Published: June 2019

German organizations are among the last Palestine solidarity groups in Europe to have embraced the call for Boycott, Divestment and Sanctions (BDS), launched in 2005. Pro-Israel German groups have been quick to respond with aggressive rhetoric equating a BDS-favorable stance with Nazism. The vilification of the movement has had the unintended consequence of inserting BDS into German politics, both at federal and local levels. Select case studies show that the BDS debate in Germany has developed somewhat differently than in other European countries, and that religious discourse is significant in shaping attitudes to Israel and Palestine. While the Palestine solidarity movement tends to single out the “Anti-Germans”—a pro-Israel formation that grew out of the Left after the reunification of Germany—as the major culprit, it is in fact conservative Christian, mostly Evangelical, organizations that are largely responsible for discouraging BDS activism.
“Always the same unrememberable revelation”: Thoreau’s Telegraph Harp, the Development of an Immanent Romantic Secularism, and Golden Age Children’s Literature
Authors: Floyd Courtney A.
Published: June 2019

Courtney A. Floyd, “‘Always the same unrememberable revelation’: Thoreau’s Telegraph Harp, the Development of an Immanent Romantic Secularism, and Golden Age Children’s Literature” (pp. 30–53)

In this essay, I analyze Henry David Thoreau’s references to and use of the telegraph, Aeolian harp, and telegraph harp in his journals between the years 1851 and 1853, A Week on the Concord and Merrimack Rivers (1849), and Walden (1854). I argue that the figure of the telegraph harp, though only briefly mentioned in Thoreau’s published works, represents a significant reworking of Romantic sensibility into a modern, immanent, and secular narrative of mundane transcendence that undergirds his particular transcendentalism. Thoreau obfuscates the material modernity of the telegraph harp even as he rescripts its very materiality. His diction in passages about the telegraph harp implies a sort of transcendence but grounds that transcendence in the natural landscape and a physical symbol of modern technology, establishing a conceptual legacy that informs not only second-generation transcendentalism, but also and unexpectedly, Golden Age children’s literature of the late nineteenth and early twentieth centuries.
Serpins: Genome-Wide Characterisation and Expression Analysis of the Serine Protease Inhibitor Family inTriticum aestivum
Authors: Benbow Harriet R , Jermiin Lars S , Doohan Fiona M
Published: June 2019

The serine protease inhibitor (serpin) gene family is the largest family of protease inhibitors. Serine protease inhibitors have an active, but under-characterized, role in grain development and defense against pathogen attack in cereal crops. By exploiting publicly available genomic, transcriptomic and proteomic data for wheat (Triticum aestivum), we have identified and annotated the entire ’serpinome’ of wheat and constructed a high-quality and robust phylogenetic tree of the gene family, identifying paralogous and homeologous clades from the hexaploid wheat genome, including the Serpin-Z group that have been well characterized in barley. Using publicly available RNAseq data (http://www.wheat-expression.com/), expression profiles of the wheat serpins were explored across a variety of tissues from the developing grain, spikelet and spike. We show that the SERPIN-Z clade, among others, are highly expressed during grain development, and that there is homeologous and paralogous functional redundancy in this gene family. Further to their role in grain development, serpins play an important but under-explored role in response to fungal pathogens. Using 13 RNAseq datasets of wheat tissues infected by fungal pathogens, we identified 37 serpins with a significant disease response. The majority of the disease-responsive serpins were upregulated by Fusarium graminearum, a destructive fungal pathogen that attacks the spike and developing grain of wheat. As serpins are ubiquitous in wheat grain, the genes encoding serpins may be linked to grain development, with their disease response a result of pleiotropy.
Engaging Indigenous Communities in the Classroom: The Eastern Shawnee Tribe of Oklahoma and Miami University
Authors: Dushane Robin , Garner Sandra , Smitson Casey , Banks Jason
Published: June 2019

This article explores the concepts of community driven research and experiential learning in the context of partnerships between universities and indigenous communities. Specifically, this article examines the successes and challenges of Miami University’s partnership with the Eastern Shawnee Tribe of Oklahoma (ESTOO). Taking a dialogic approach, a professor, two students and a tribal leader, reflect on their experiences within the partnership and provide insight into how partnerships between universities and indigenous communities might develop, function, and serve both students and community members.
Oral kontraseptif kullanan kadınlarda inflamatuvar belirteçlerinin ve adezyon moleküllerinin değişimi
Authors: ÖZSÜRMELİ Mehmet , BAŞTU Ercan , COMBA Cihan , SUCU Mete , ARSLAN Erol , MISIRLIOĞLU Selahattin , ÇELİK Faruk , ZEYBEK Şakir Ümit , BÜYÜKÖREN Ahmet
Published: June 2019

Amaç: Bu çalışmanın amacı, oral kontraseptiflerin adezyon moleküllerinin serum seviyelerine olan etkisini araştırarak, sentetik östrojenlerin ateroskleroza karşı koruyucu etkisi olup olmadığı saptamaktır.Gereç ve Yöntem: Ek hastalığı bulunmayan, kontrasepsiyon amaçlı en az 3 aydır oral kontraseptif kullanan, 18-45 yaş aralığında olan hastaların serum interlökin 6 (İL-6), tümör nekrozis faktör alfa (TNF alfa), damarsal hücre yapışma molekülü 1 (VCAM-1), hücreler arası adezyon molekülü (ICAM-1), E selektin, P selektin, c reaktif protein (CRP) seviyeleri ve eritrosit sedimentasyon hızları (ESH); ek hastalığı bulunmayan, düzenli adet gören, 18-45 yaş aralığında olan sağlıklı gönüllülerle karşılaştırıldı.Bulgular: Her iki grubun VCAM-1, ICAM-1, E selektin, P selektin, TNF alfa, İL 6, ESH seviyeleri arasında anlamlı fark saptanmadı. Oral kontraseptif kullanan grupta serum CRP seviyeleri anlamlı olarak daha yüksek saptandı.Sonuç: Oral kontraseptiflerin adezyon moleküllerinin serum seviyelerini değiştirdiği gösterilemiştir. Serum crp seviyelerinin değişimleri ise karaciğer ilk geçiş etkisine bağlanmaktadır.
Evaluation of congenital anomalies accompanying to gastrointestinal system surgical pathologies
Authors: KONAK Murat , SERT Ahmet , GÜNDÜZ Metin , SOYLU Hanifi , SÜNDÜS UYGUN Saime
Published: June 2019

Purpose: The aim of this study was to review accompanied congenital anomalies to gastrointestinal pathologies. Materials and Methods: The medical records of patients who were admitted to neonatal intensive care unit with gastrointestinal system surgical pathologies during 2015-2018 were retrospectively evaluated for associated congenital anomalies.Results: 67 patients were identified during the study period. The most common gastrointestinal system pathology was anal atresia in 15 cases (22.4%), followed by diaphragmatic hernia in 14 cases (20.9%), esophageal atresia (n:10) and ileal atresia (n:10) (14.9%). Thirty two patients (48.8%) have had accompanied congenital anomalies to gastrointestinal system pathologies. Congenital heart disease was the most common anomaly and the most frequent one was atrial septal defect in 18 cases (26.8%). In addition, there was complex congenital heart disease in (n:13) 19.4%. In 12 patients (17.9%), accompanied extracardiac anomalies were detected. Hydronephrosis and sludge in gall bladder were detected in three patients (4.5%). Vesicoureteral reflux or ectopic kidney or polysplenia was detected as a separate anomaly in each case. In our cases, prematurity rate was found in 54%.Conclusion: Gastrointestinal system pathologies are frequently associated with multiple anomalies, especially with congenital heart diseases. In addition, these patients are likely to be preterm baby.
Screening results of the psychomotor development of children at inpatient unit of a training and research hospital in Turkey
Authors: KÜTÜK Meryem Özlem , GÖKÇEN Cem , GÜLER AKSU Gülen , AKIN Fatih , KARDAŞ Ayşenur , SARP Ayşe Sevde , TUFAN Ali Evren
Published: June 2019

Purpose: This study  aimed to assess the psychomotor development of inpatient children in the pediatrics clinic and referring the children to the child and adolescent psychiatry clinic who have problems in their developmental process for early interventionMaterials and Methods: Four hundred twenty children between 4-72 months at inpatient unit of the department of Pediatrics at Konya State Research hospital were included in the present study. A child development specialist who was unaware of the history and neurological examination of the cases administered Denver developmental screening test (DDST) II to all children once.  Children who were found to be abnormal or questionable were further evaluated by the child and adolescent psychiatrist. Results: Three hundred forty five (82%) were found to be ‘normal’, 12 (2.8%) were found to be ‘questionable’ and 64 (15.2%) cases were found to be ‘abnormal’ with regard to DDST II. Post evaluation of questionable and abnormal cases by the child and adolescent psychiatrist, 26 cases were referred to special education institutions with the diagnosis of global developmental delay and 2 cases with the diagnosis of pervasive developmental disorder. Conclusion: It is important to apply screening tests for developmental evaluation to each child at inpatient pediatric clinics in order to diagnose developmental delays earlier. It has critical importance of early diagnosis and intervention in children who have developmental delay in the interest of proper treatment for them.
Anadolu Üniversitesi Öğrencilerinin Kent Konseyi Algısı
Authors: ŞAHYAR AKDEMİR Duru
Published: June 2019

5393 sayılı “Belediye
Kanunu” ile kurulan kent konseyleri yönetmeliğinin altıncı maddesi kent
konseylerinin görevlerini tanımlamaktadır. Bu görevlerden bir tanesinin de
“çocukların, gençlerin, kadınların ve engellilerin toplumsal yaşamdaki
etkinliklerini arttırmak ve yerel karar alma mekanizmalarında aktif rol
almalarını sağlamak” olduğu belirtilmiştir. Ancak gençlerin kent konseyi gibi
yerel katılım mekanizmaları aracılığıyla karar alma süreçlerine katılımları
oldukça düşüktür. Bunun nedenlerinden biri de gençlerin yerel karar alma süreçlerine
nasıl katılacakları hakkında bilgi sahibi olmamalarıdır. Çalışmada Anadolu
Üniversitesi öğrencilerinin genel olarak kent konseyleri ve özelde ise
Eskişehir’de yer alan kent konseylerine yönelik bilgi, algı ve tutumlarının
tespit edilmesi amacıyla gerçekleştirilmiş olan saha çalışması sonuçlarına yer
verilmiştir. 1005 kişiyle anket tekniği uygulanarak elde edilen sonuçlar
gençlerin kent konseylerine yönelik algılarının belirlenmesi açısından büyük
önem arz etmektedir.
Understanding the Reasons for Class Repetition in an English Language Preparatory Department
Authors: YASTIBAŞ Ahmet Erdost
Published: June 2019

Repeaters experienced some unknown difficulties in learning English in the English language preparatory department (ELPD) of a Turkish university. Therefore, the present study aimed to find out what the difficultieswere and how the difficulties were experienced. The present study was designed as a hermeneutic phenomenological study. Sixteen students who studied in a level once or more than once participated into the study. The data were collected with semi-structured interviews and content-analyzed.Different strategies like thick description and decentralization were used for the trustworthiness of the study. The findings indicated that six sources led to the students’ fear of failure and influenced their perception of education negatively, which resulted in studying in a level many times.
Azərbaycan Xalq Cümhuriyyəti: “AZƏRTAC”ın yaranma zərurəti və keçdiyi yol
Authors: AHMADOV Namiq
Published: June 2019

Makalenin konusu Azerbaycan Halk Cumhuriyeti’nin yadigarı ve Doğu’da
ilk haber ajanslarından biri olan AzerTAc’ın geçtiği zor, ama şerefli yoldur.
Ajansın oluşum dönemini 3 aşamaya ayırabiliriz. Birinci aşama 1920 senesinin
Mart-Nisan aylarını kapsıyor. Milli haber ajansı ilk haberlerini bu dönemde
yayınlamaya başlamıştır. İkinci aşama zamansal açıdan uzun dönemi kapsıyor – tüm
Sovyet Dönemi’ni. Üçüncü aşamaysa ikinci özgürlüğümüze kavuştuğumuz dönemi
kapsıyor. Bu dönemde – 1992 senesinde AzerTAc tarihi ismine geri dönmüştür. Ama
özgürlüğün ilk yılları onun için çok zor olmuş, ajans birden bire kendi
bütçesinden yönetilmeye başlayınca, ciddi ekonomik sorunlar çıkmıştır. 1993
senesinde Haydar Aliyev’in Azerbaycan’da siyasi hakimiyete dönüşü AzerTAc’ın
faaliyetinde yeni gelişme çağı olmuştur.
Ortaokullarda Örgütsel Sinizmin Yordayıcısı Olarak Örgütsel Güven
Authors: UYAR Burcu , ZAFER GÜNEŞ Demet
Published: June 2019

Bu
çalışmanın temel amacı örgütsel sinizm ile örgütsel güven arasındaki ilişkiyi
araştırmaktır. İlişkisel tarama modelindeki araştırmanın evrenini; İstanbul ili
Küçükçekmece ilçesinde bulunan ortaokul öğretmenleri oluşturmakta olup,
araştırmanın örneklemi ise n=390 (262 kadın; 128 erkek) ortaokul öğretmenidir.
Çalışmada veri toplama aracı olarak kişisel bilgi formu,  "Okullarda Örgütsel Güven Ölçeği" ve
"Örgütsel Sinizm Ölçeği" kullanılmıştır. Sosyal bilimler için
geliştirilen bir istatistik paket programı ile veriler analiz edilmiştir. Verilerin
analizinde aritmetik ortalama, standart sapma, Pearson Korelasyon Testi ve
doğrusal regresyon analizi kullanılmıştır. Araştırmada ortaokullarda görev
yapan öğretmenlerde örgütsel güven ve örgütsel sinizm düzeyleri arasında
istatistiksel açıdan negatif yönde, yüksek bir ilişki tespit edilmiştir. Ayrıca
yapılan regresyon analizi sonucunda ortaokul öğretmenlerinin örgütsel güven
düzeylerinin örgütsel sinizm düzeylerini yordama gücü %52 bulunmuştur.
BALIKESİRLİ RÂSİH VE BÜLGATÜ’L-AHBÂB ADLI ESERİ
Authors: ÖNLER Selim
Published: June 2019

19.
yüzyıla kadar yüksek zümreye özgü olan adabımuaşeret kitapları, teknik gelişmeler
ve Batılılaşma hareketleriyle beraber halkın da ulaşabildiği eserler haline
gelmiştir. Bu dönemden önce yazılmış eserlerden biri de Balıkesirli Râsih
tarafından yazılan Bülgatü’l-Ahbâb adlı eserdir. 17 ila 18. yüzyıllarda yaşamış
olan, Râsih Ahmed Beg olarak da bilinen Balıkesirli Râsih’in, mensubu olduğu
köklü aileye rağmen, hayatı hakkında henüz fazla bilgiye sahip değiliz.
Kendisine atfedilen üstine redifli gazeli dışında Râsih’in diğer eserleri fazla
bilinmemekle beraber, bunlardan birisi de Bülgatü’l-Ahbâb adlı, görgü
kurallarından tarihsel olaylara kadar pek çok farklı konudan bahsettiği sosyal
ve siyasal eseridir. Bugüne kadar hiç çalışılmamış olan Bülgatü’l-Ahbâb’ın pek
çok nüshası bulunmaktadır. Bu çalışmada Râsih ve Bülgatü’l-Ahbâb hakkında
bilgiler verilmeye çalışılacaktır.
Tari Glipang sebagai Sarana Peningkatan Konsentrasi Kinestetik Tunagrahita
Authors: Restian Arina , Aini Dian Fitri Nur
Published: June 2019

Usia sekolah dasar merupakan fase perkembangan awal pada anak untukmengembangkan kemampuan atau kecerdasannya. Peserta didik memilikikemampuan berbeda-beda yang dipengaruhi oleh beberapa faktor. Kecerdasan pada manusia khususnya anak usia sekolah dasar meliputi 9 jenis kecerdasan salah satunya adalah kecerdasan kinestetik. Kecerdasan kinestetik pada usia sekolah dasar secara umum berkembang lebih cepat dibandingkan kecerdasan yang lain. Hal ini dikarenakan karakteristik anak usia sekolah dasar cenderung lebih menyukai kegiatan yang bergerak misalnya berlari dan menari. Namun pada anak tunagrahita, kemampuan motoriknya cenderung berkembang lebih lambat dibandingkan dengananak regular. Tunagrahita memiliki keterbatasan dalam memfokuskan diri pada sesuatu tidak lebih dari setengah jam sehingga mereka sulit berkonsentrasi. Keterlambatan perkembangan kemampuan motorik yang dialami oleh tunagrahita juga berpengaruh terhadap konsentrasi kinestetiknya. Anak cenderung sulit menghafal gerakan-gerakan yang terdapat pada pembelajaran yang mengharuskan mereka bergerak secara bersamaan dengan siswa lain misalnya pada kegiatan senam dan tari. Salah satu upaya yang dapat dilakukan untuk melatih konsentrasi kinestetik pada anak tunagrahita adalah melalui kegiatan menari. Tari memiliki tujuan untuk mengembangkan pribadi peserta didik. Salah satu jenis tarian yang dapat digunakan sebagai sarana terapi tunagrahita adalah Tari Glipang. Tari Glipang merupakan tarian yang berasal dari Probolinggo. Tari Glipang memiliki 13 tahapan yang diterapkan dalam pembelajaran seni yang dapat digunakan sebagai terapi untuk anak tunagrahita. Penerapan gerakan Tari Glipang pada anak grahitadapat membantu mereka meredakan emosi dan berpengaruh pada konsentrasinya. Selain itu, Tari Glipang juga cenderung memiliki gerakan yang fokus ke pengaturan pernapasan. Pengaturan pernapasan yang baik akan melancarkan peredaran darah yang secara langsung berpengaruh pada meningkatnya konsentrasi anak.
Nilai Sosial Masyarakat Madura dalam Kumpulan Syair Lagu Daerah Madura
Authors: Ambarwati Putri , Wardah Huriyatul , Sofian Muhammad Ovin
Published: June 2019

Penelitian ini membahas mengenai nilai sosial masyarakat Madura dalam kumpulan syair lagu daerah Madura. Kajian ini dilakukan dengan tujuan memaparkan tentang nilai-nilai sosial dalam kehidupan masyarakat Madura yang tercermin melalui lagu daerahnya. Dengan adanya penelitian ini diharapkan mampu memberikan manfaat kepada masyarakat agar dapat memaknai lagu daerah tersebut secara mendalam dengan cara mengambil pesan yang disampaikan dalam lagu serta meluruskan streotip orang di luar Madura terhadap masyarakat Madura. Dalam penelitian ini menggunakan pendekatan etika yang sejalan dengan nilai-nilai sosial masyarakat yang dibahas. Teori yang digunakan yaitu teori dari Immanuel Kant dan John Stuart Mill yang membahas mengenai etika sosial. Penelitian ini menggunakan jenis penelitian kualitatif dan sumber data yang digunakan berupa sumber data kontekstual. Pembahasan yang dihasilkan dari penelitian ini yaitu membahas mengenai nilai-nilai sosial yang terdapat dalam beberapa lagu daerah Madura yaitu lagu “Caca aghuna, Re-sere penang, Bhing ana‟, Pajjher Lagghu, dan Tandhu‟ Majheng. Nilai-nilai yang terefleksikan dalam lagu tersebut yaitu terdiri dari nilai kepedulian dan nilai tanggung jawab.
Pengembangan Teknik Peran Seorang Aktor Untuk Pementasan Monolog Melalui Sistem Stanislavski dalam Buku an Actor Prepares and Building a Character
Authors: Marciano Roci
Published: June 2019

Tujuan penelitian Teknik Peran Seorang Aktor Untuk Pementasan Monolog Melalui Sistem Stanislavski An Actor Preapares And Building A Character ini dilakukan ialah, untuk mengembangkan model pembelajaran pada mata kuliah Totalitas Keaktoran yang ditempuh oleh mahasiswa semester lima. Pengembangan Teknik Peran Seorang Aktor Untuk Pementasan Monolog Melalui Metode Stanislavski An Actor Preapers And Building A Character penting untuk di pelajari saat ini. Karena penelitian memberikan dampak positif bagi seorang mahasiswa khususnya dan masyarakat luas pada umumnya yang mengambil minat keaktoran. Kecerdasan yang bisa dipelajari dalam belajar monolog tentu saja bukan hanya demi keberanian seorang aktor tampil sendirian di atas panggung dengan menyampaikan kisah atau cerita. Tetapi nilai yang paling berharga dari penemuan teknik peran ini adalah, seorang aktor bisa memulai pelatihannya dengan tersistem, teratur dan terprogram. Karena monolog juga memiliki dampak yang positif untuk dipelajari, seperti sebagai mahasiswa atau manusia mampu menghapalkan hasil pemikiran seorang penulis naskah, merespon segala tatanan artistik dengan kecerdasan lahiriah dan batiniah sebagai perangkat keaktoran untuk disampaikan kepada penonton. Oleh sebab itu teknik-teknik dalam pelatihan seorang aktor untuk mewujudkan pementasan monolog dan monodrama tentu saja dibutuhkan, sehingga penelitian ini akan berguna bagi mahasiswa STKW Surabaya khususnya, dan seluruh mahasiswa teater yang ingin pentas monolog pada umumnya.
Pellevé™ vs Lipiflow™ MGD-Related Dry Eye Treatment Study: The ThermaLid™ Procedure
Authors: Jaccoma Edward Hall , Litherland Craig , Jaccoma Andrew , Ahmed Aseef
Published: June 2019

Objective: To assess the safety and efficacy of the Pellevé Wrinkle Treatment System as compared to LipiFlow, for treatment of dry eye syndrome due to meibomian gland dysfunction (MGD).

Materials and Methods: In this split face, randomized study, ten patients who met specific criteria for inclusion were followed after treatment with the Pellevé Wrinkle Reduction System (what the authors have dubbed the "thermaLid Procedure") and a standard LipiFlow procedure performed the same day, with 1 and 3 months follow-up. Pre- and post- treatment MGD was assessed using a variety of subjective and objective measurements.  

Results: The function of the meibomian glands improved significantly from baseline to 3 months for both thermaLid and Lipiflow treated eyes, with no significant difference between them, as measured by MGE grading, wax plug scoring, Standard Patient Evaluation of Eye Dryness (SPEED) and Ocular Surface Disease Index (OSDI) scoring. A significant change in conjunctival staining was found after both treatments at the 1-month time point but not the 3-month time point. thermaLid but not Lipiflow treatment, significantly decreased MARX line measurements at 3-months. Lipiview, Non-Invasive Tear Breakup Time (NITBUT), corneal surface staining, Tear Osmolarity, and anesthetic Schirmer's testing did not show statistically significant improvement, nor differences between treatment modalities.

Conclusions: thermaLid treatment of the eyelids appears to show efficacy similar to Lipiflow treatment in reducing symptoms, reducing wax plugging and improving the number of functioning MGs as well as reducing conjunctival staining in MGD related dry eye disease.
El microsistema de protección de los consumidores. Tensiones con el Código Civil
Authors: Alvarez Agustín
Published: June 2019

I.- Relaciones entre el Derecho de protección de los consumidores y el Código Civil: 1.- Microsistema y autonomía. 2.- Evolución e importancia de la protección especial al consumidor. 3.- Jerarquía constitucional del derecho de protección a los consumidores. 4.- Tensiones entre la Ley de Defensa del Consumidor y el Código Civil después de la Ley 26.361. Generalidades. II.- La ley 26.361: 1.- Principales modificaciones. 2.- Regulaciones que se mantienen. III.- La relación de consumo: 1.- La relación de consumo como ámbito de aplicación de la ley. 2.- Consumidores. 3.- Proveedores. 4.- De la búsqueda del equilibrio contractual a la tutela de la relación de consumo. IV.- Conclusiones. V.- Bibliografía.
Reflexiones sobre la noción de consumidor inmobiliario y los vicios en la la Ley de Defensa del Consumidor
Authors: Arias Cáu Esteban Javier
Published: June 2019

I. Introducción. II. Las etapas de protección de la compraventa inmobiliaria. 1. El Código Civil. 2. La ley 24.240. 3. La ley 26.361. III. Nuestra opinión
La prescripción liberatoria en la Ley de Defensa del Consumidor
Authors: Alvarez Agustín , Brandalise Carolina , Cornet Oliva Victoria , Garzino María Constanza
Published: June 2019

I. Introducción. II. Generalidades III. La prescripción en la relación de consumo. 1. Acciones comprendidas. 2. El principio in dubio pro consumidor y la naturaleza del régimen. 3. Plazo de prescripción y ámbito subjetivo. 4. Interrupción: importancia y efectos. IV. Nuestra opinión. V. Conclusiones.
Antidiabetic Medications and Mortality Risk in Individuals With Pancreatic Cancer–Related Diabetes and Postpancreatitis Diabetes: A Nationwide Cohort Study
Authors: Cho Jaelim , Scragg Robert , Pandol Stephen J. , Goodarzi Mark O. , Petrov Maxim S.
Published: June 2019

OBJECTIVE

There are no specific treatment guidelines for diabetes of the exocrine pancreas. High-quality studies are warranted to investigate whether the use of antidiabetic medications has survival benefit in individuals with diabetes of the exocrine pancreas. The objective was to determine the risk of mortality associated with the use of antidiabetic medications in individuals with pancreatic cancer–related diabetes (PCRD) and postpancreatitis diabetes mellitus (PPDM).

RESEARCH DESIGN AND METHODS

Nationwide pharmaceutical dispensing data (2006–2015) linked to hospital discharge data were used to identify 1,862 individuals with PCRD or PPDM. Multivariable Cox regression analysis was conducted, and the risk was expressed as hazard ratios and 95% CIs. A 6-month lag was used to minimize reverse causality.

RESULTS

In individuals with PCRD, ever users of metformin (adjusted hazard ratio 0.54; 95% CI 0.46–0.63) and ever users of insulin (adjusted hazard ratio 0.46; 95% CI 0.39–0.55) had significantly lower risks of mortality compared with never users of antidiabetic medications. These associations attenuated toward the null with the use of a 6-month lag. In individuals with PPDM, ever users of metformin had a significantly lower risk of mortality (adjusted hazard ratio 0.51; 95% CI 0.36–0.70), whereas ever-users of insulin did not have a significantly changed risk of mortality (adjusted hazard ratio 0.75; 95% CI 0.49–1.14) compared with never users of antidiabetic medications. The former association remained significant with the use of a 6-month lag.

CONCLUSIONS

Metformin promotes a survival benefit in individuals with PPDM but not PCRD. Reverse causality may play a role in the association between insulin use and mortality in PCRD.
Prestehumor i norske medier i 50 år
Authors: Repstad Pål
Published: June 2019

This chapter analyzes three Norwegian radio and TV series that feature clergy members as main characters: Rolv Wesenlund’s portrait of bishop Fjertnes from the late 1960s, the three comedians Kirkvaag, Lystad and Mjøen (KLM) and their slapstick sketches of the clergy from the 1980s and 90s, and the series Presten (The Vicar) from 2017. Three main types of character are identified. In some scenes, especially in KLM, the clergy make fun of religious symbols. Two other types are more common, however. One is the strict, solemn clergyman or clergywoman who nevertheless turns out to widen their role, sometimes in happy self-expression, sometimes revealing double standards. The other is the cool and dogmatically open priest, eager to include everybody. The last type becomes predominant over time, but the development is not quite linear. The new series Presten presents the most nuanced and kind picture, maybe because the clergy has less influence in society, so the need for harsh satire is diminishing. The chapter also includes analyses of how the series have been received by church leaders and by the general public.