bluuebunny/crossref_metadata_2025 huggingface dataset:
Tingkat Kualitas Hidup Pasien Setelah IMA dengan Menjalani Program Rehabilitasi Jantung Berbasis Latihan (Literature review)
Authors: Safitri Ulandari  , Nurwahyuni Munir  , Wa Ode Sri Asnaniar
Published: July 2023

Cardiac Rehabilitation (CR) tertutama dirancang untuk menanggulangi bebas fisiologi serta psikologis penyakit jantung. Tujuan utama rehabilitasi jantung yaitu untuk memaksimalkan fungsi fisik, dan untuk meningkatkan kualitas hidup mereka serta dapat mengurangi kekambuhan kejadian utama jantung serta serebrovaskular. Tujuan dari penelitian ini adalah melakukan literature review untuk mengetahui tingkat kualitas hidup pada penderita setelah IMA dengan menjalani rehabilitasi jantung berbasis latihan. Desain penelitian ini menggunakan metode literature review, dengan pencarian yang dipublikasikan pada tahun 2010-2020 melalui media elektronik pubmed, proquest, dan science direct, dengan keywords “Exercise Cardiac Rehabilitation”,“Myocardial Infarction”, dan “Quality of Life” dengan filter full text, open accses, dan berdasarkan subjek keywords. Hasil yang diperoleh ada 9 artikel penelitian dengan menggunakan metode quasi experimen , cohort prospective dan restropektive, pre experimen, non equivalent, true experimen. Pada 9 artikel penelitian menyimpulkan bahwa adanya peningkatan kualitas hidup yang terjadi pada pasien setelah IMA yang mengikuti rehabilitasi jantung berbasis latihan, dengan jangka waktu yang berbeda-beda. Kesimpulan dari penelitian ini adalah Rehabilitasi jantung yang menggunakan exercise atau latihan fisik dapat meningkatkan kualitas hidup pasien dengan lebih baik, rehabilitasi jantung dinilai dalam beberapa tahap dan dalam waktu yang ditentukan sesuai dengan gejala yang dialami pasien. beberapa penelitian sebelumnya mengalami keterhambatan karena alat yang digunakan pada rehabilitasi jantung kurang, maka dari itu rehabilitasi jantung juga dapat dilakukan di rumah sakit atau dirumah dengan beberapa latihan fisik ringan yang di sarankan oleh ahli dan dalam pengawasan langsung.
Особистісне майбутнє внутрішньо переміщених осіб: стратегії конструювання
Authors: Dibrova Valeriia
Published: July 2023

Актуальність. Проблема вимушеного переселення є актуальною в умовах сьогодення. Ще від початку війни у 2014 році кількість внутрішньо переміщених осіб (ВПО) в Україні становила близько 1,5 млн осіб, нині ж через повномасштабне вторгнення ця цифра невпинно збільшується. Психологічна травматизація переселенців і вимушений характер переселення привертають увагу дослідників та психологів до проблем надання психологічної допомоги внутрішньо переміщеним особам та адаптації їх до життя на новому місці. Оскільки переміщення та побудова подальшого життя спрямовані в часовий період майбутнього, доцільно розглядати характеристики майбутнього ВПО і стратегії, які вони використовують для його конструювання.

Метою статті є визначення характеристик особистісного майбутнього ВПО і стратегій, які вони застосовують для його конструювання.

Методологія: порівняльний аналіз письмових наративів про майбутнє ВПО і місцевих мешканців.

За результатами проведеного дослідження наративів внутрішньо переміщених осіб виявлено емоційну валентність їхнього ставлення до майбутнього, комплексність бачення ними особистісного майбутнього та рівень досяжності майбутнього, описаного в авторських історіях. Визначено стратегії конструювання особистісного майбутнього, до яких вдаються ВПО, та специфіку їх використання.

Висновки та перспективи подальших досліджень. З’ясовано, що історіям про майбутнє ВПО більшою мірою притаманна негативна емоційна валентність порівняно з історіями осіб, які не мають досвіду вимушеного переселення. Бачення майбутнього ВПО є порівняно менш комплексним, у своїх історіях вони частіше описують абстрактне майбутнє. Різниця у використанні стратегій конструювання майбутнього внутрішньо переміщеними особами і місцевими мешканцями полягає в більшій поширеності в наративах ВПО стратегії уникання майбутнього. Також для ВПО більш характерний варіант соціального конструювання майбутнього з наголосом на піклуванні про значущих інших.
Analisis Faktor Fasilitas Pendidikan Anak Usia Dini dengan Metode Structural Partial Least Square
Authors: Panji Yudha Rivo , Noza Novi Andriyati
Published: July 2023

Fasilitas pendidikan dalam proses pembelajaran di sekolah diyakini mampu meningkatkan prestasi dan kualitas siswa. Dengan fasilitas sekolah yang mendukung siswa untuk belajar mandiri dan tidak hanya mengandalkan proses belajar mengajar di sekolah. Penulis melakukan penelitian ini untuk mengetahui apakah ada hubungan antara ketersediaan fasilitas pendidikan, kondisi fisik, kebutuhan siswa dan juga kebutuhan tenaga pendidik di fasilitas pendidikan. Metode yang dapat digunakan dalam penelitian ini adalah dengan menggunakan analisis Structural Equation Modeling (SEM) berdasarkan varian yaitu Partial Least Square (PLS). SEM dengan variance-based PLS dapat menangani dua kondisi yaitu kondisi dengan faktor yang tidak ditentukan dan kondisi dimana solusi tidak dapat diterima. Penelitian ini menggunakan program komputer pintar PLS 4.0 dan menentukan variabel yang signifikan pada fasilitas pendidikan (Y) di TK Kec. Tarogong Kidul di Garut. Berdasarkan hasil penelitian yang telah dilakukan diperoleh variabel yang paling mempengaruhi adalah kondisi fisik dan kebutuhan tenaga pendidik.
Pengaruh Implementasi Kurikulum Merdeka di PAUD terhadap Tanggung Jawab dan Disiplin Pada Anak
Authors: Cahyati Nika
Published: July 2023

Tujuan dari penelitian ini untuk agar dapat melihat keefektifan kurikulum merdeka yang digunakan saat ini untuk perkembangan tanggung jawab dan disiplin pada anak sebagaimana implementasi kurikulum merdeka di terapkan dalam PAUD, karena dasar dari adanya kurikulum merdeka ini adalah untuk membentuk rasa tangung jawab anak dan disiplin anak agar menjadi lebih baik. Jenis penelitian ini adalah penelitian kuasi eksperimen (Quasi-Experimental Research). Penelitian ini dilaksanakan di sekolah penggerak di Kabupaten Kuningan Provinsi Jawa Barat. Waktu Penelitian  dilakukan pada semester I yang kurang lebih berlangsung selama 2 bulan Meliputi perencanaan kegiatan penelitian dan penerapan kegiatan penelitian serta pengambilan data. Populasi dalam penelitian ini yaitu seluruh anak yang berada di sekolah penggerak kabupaten Kuningan pada tahun ajaran 2023/2024 yang memiliki karakteristik yang sama. Sampel untuk penelitian ini yaitu dua sekolah kelompok eksperimen dan dua sekolah sebagai kelompok kontrol, hasil penelitian bahwa anak yang menggunakan kurikulum merdeka lebih memiliki tanggung jawab dan disiplin yang tinggi dari pada yang belum, kerena melalui keurikulum merdeka terdapat sebuat pembiasaan dari pelajar profil pancasila, sehingga implementasinya lebih mudah diterapkan pada anak.
Efektivitas Media Rubattri Untuk Menstimulasi Kecerdasan Logika Matematika Pada Anak Usia Dini
Authors: Asriati Liana , Kristiana Dian , Kristiana Dian , Azzam Muttaqin Muhammad
Published: July 2023

Tujuan dari riset ini ialah untuk melihat keefektifan media rubattri dalam mengembangkan penalaran matematis Anak Usia Dini. Riset ini mengaplikasikan desain one-group pretest and posttest terhadap kelompok subjek eksperimen yang mendapat treatmen. Dalam penelitian ini, sampel diambil dari 14 anak (7 perempun dan 7 laki-laki) yang berusia antara 5 dan 6tahun. Observasi an dokumentasi menjadi metode dalam menghimpun data dalam riset ini. Uji efektivitas, uji normalitas, dan hipotesis statistik adalah metode untuk manganalisa data penelitian. Hasil uji normalitas membuktikan dataa tersebar dengan normal yakni signifikansi  pretest 0,255 dan posttest 0,225 (˃) 0,05. Temuan penelitian menunjukkan bahwa media rubattri secara signifikan meningkatkan kemampuan logika matematika anak usia dini. Hipotesis 0 (H0) tidak diterima dan hipotesis alternatif (Ha) diterimayang dibuktikan dengan nilai signifikansi kecerdasan logika matematis anak 0,000˂0,05. Hal ini menunjukkan bahwsanya media Rubattri bermanfaat untuk menstimulasi kemampuan logis matematis pada Anak Usia Dini.
Analysis of Excellent Response, Persistent Disease and Recurrent Diseases of Radioiodine Treatment on Differentiated Thyroid Carcinoma Patients- 42 Years’ Experience at NINMAS
Authors: Begum Fatima , Ferdous Jasmin , Jabin Zeenat , Sultana Sadia , Salam Sadia , Bailey Shamsun Nahar , Begum Shamim Momtaz Ferdousi , Nahar Nurun
Published: July 2023

Background: Radioiodine treatment in thyroidectomized differentiated thyroid carcinoma (DTC) patients was introduced in the world in 1940s and in Bangladesh in 1980. Long experience of treatment and lifelong follow up of DTC patients with proper documentation of medical records enriched the archive of the thyroid division of National Institute of Nuclear Medicine & Allied Sciences (NINMAS).
Aims: To evaluate the response of radioiodine treatment in DTC patients at NINMAS and   analyze the outcome and prognostic factors in this cohort of patients in a single institute of a developing country.
Patients and Methods: This is a retrospective cohort study. A total of 7525 patients with DTC received RAI ablation therapy from 1980-2021 at NINMAS, among them 5448 patients were treated with radioiodine from 1980-2017. Data were obtained from the medical records of 3482 DTC patients who were followed up until 2021 and all relevant data were available. Demographical, histopathological, surgical, radioiodine ablation doses of 131I, serum biomarkers thyroglobulin (Tg), antithyroglobulin antibody (TgAb) and biochemical investigation data were analyzed systematically. Age, gender, tumor size, presence of local and distant metastases at presentation, extrathyroidal extension (ETE), disease recurrence, and cancer-specific survival were also evaluated. Risk stratifications for recurrence and staging were calculated for dosing of radioiodine. The single dose of radioiodine ranged from 30 mCi to 200 mCi was given according to the postsurgical risk assessment. Repeated doses of radioiodine were given in the cases of persistent disease (PD) and recurrent disease (RD).
Results: The median age of DTC patients was 38 years, with a range of 5-87 years (39.90± 12.67 years), with the majority of patients falling within the 30-39 age group. The ratio of female to male was 3.74:1. Compared to the previous decade, patient number increased about 72 and 16-folds in relation to the 1980s and 1990s respectively at this institute. Papillary thyroid carcinoma (PTC) and follicular variant of thyroid carcinoma (FVPTC) together were evaluated in 3311(95.09%) cases and follicular thyroid carcinoma (FTC) was diagnosed in 171(4.91%). Excellent response (ER) was observed by a single dose of radioiodine ablation in 2853(81.94%) and PD and RD were noted in 388(11.14%) and 241(6.92%) respectively. Tg and TgAb levels at pre-therapy state were significantly higher in patients who had PD (P <0.000) and RD (P <0.000).
Conclusion: Significant increase in the number of DTC patients was observed in the last two decades. ER was noted in 81.94% with a single dose of radioiodine. Serum Tg and TgAb are two prognostic factors for disease outcomes showing high Tg and TgAb in PD and RD cases.
Bangladesh J. Nuclear Med. 25(2): 81-87, 2022
Calculation of Standardized Uptake Value (SUV) from PET-CT Image by Using In-House Developed MATLAB Software
Authors: Mahmud Khan Muntakim , Khatun M Mahfuza , Mollah Abdus Sattar , Sharif Tanima , Mim Nahid Farzana , Reza Selim
Published: July 2023

The Standardized Uptake Value (SUV) is one of the fundamental parameters to determine whether a region may be considered a “tumor” or “malignant” from PET-CT-derived images. When a measured SUV value is around 2.5, it is non-malignant. Again small tumorous areas can also show a maximum SUV of <2.5. The main objective of this study is to develop a computer program based on MATLAB for calculating SUV from PET-CT-derived images. This study also projects the way of calculating SUVs in a facile way. The study was particularly concerned with the 2D PET-CT images which were initially derived from commercial medical image processing software. Unlike the DICOM (Digital Imaging and Communications in Medicine) formatted PET-CT produced image, the study calculated these images in JPG (Joint Photographic Group) format. Each command and instruction of this program produces the selection of a region of interest (ROI) sequentially. The programming code also extracted the recognition of the desired ROI in cancerous cells. In the study, we have loaded 13 different PET-CT image samples in the software as input. These inputs were used to reach the final result by using in-house developed MATLAB code. A correlation (polynomial expression) between the calculated SUV and the acquired SUV value from commercial software had been established in order to reduce the error. It is concluded that the in-house developed MATLAB program can be used for rapid estimation of SUV value within an acceptable error range.
Bangladesh J. Nuclear Med. 25(2): 98-104, 2022
Non-Invasive Assessment of Myocardial Perfusion Abnormality in Type 2 Diabetic Patients Without Symptoms of Coronary Artery Disease by SPECT-MPI
Authors: Azam Mohammad Nurul , Sultana Sadia , Roy Sutanu , Salma Umme
Published: July 2023

Introduction: Coronary artery disease (CAD) is the most common chronic macrovascular complication of diabetes mellitus. Diabetic patients have a high incidence of silent ischemia and MI due to autonomic neuropathy. SPECT imaging is a well-established, non-invasive procedure that offers perfusion and functional information for diagnosis and risk stratification, facilitating the early detection of CAD.
Objective: To detect myocardial perfusion abnormality by SPECT-MPI in type 2 diabetic patients without symptoms of CAD.
Methods:  A total of eighteen diabetic patients with no history of typical CAD, with or without risk factors, underwent gated SPECT-MPI using 99mTc-sestaMIBI. A single-day stress–rest protocol with adenosine was done in each patient. Result: Six out of eighteen patients (33.3%) showed abnormal scans suggestive of myocardial ischemia or infarction. Four of these patients had reversible perfusion defects, one had a fixed perfusion defect, and one had a mixed defect. Among these patients, single vessel territory was involved in three patients, and three patients had involvement in double vessel territories. Regarding the summed stress score (SSS) value, most of the patients (four) had mild risk, whereas moderate and severe risk of a future cardiac event were observed in one patient each. In addition, two patients had left ventricular dysfunction (EF< 45%). Five patients with normal MPI and two patients with abnormal myocardial perfusion scans had high transient ischemic dilatation (TID). Risk factors such as male sex, hypertension, hyperlipidemia, obesity, and family history of CAD were not significantly correlated with abnormal scans. But abnormal scans were significantly related to a longer duration of diabetes (P = 0.038).
Conclusion: This study showed that despite being asymptomatic, a considerable portion of diabetic patients had perfusion abnormalities, not just ischemia but also infarctions. Moreover, some of these patients are at high risk for future cardiac events as assessed by SSS, TID, and LVEF.
Bangladesh J. Nuclear Med. 25(2): 110-116, 2022
Congenital Neck Mass: A Case Report
Authors: Ferdous Jasmin , Jabin Zeenat , Akhter Papia , Begum Fatima
Published: July 2023

Congenital goiter is a very uncommon cause of neonatal neck mass. Administration of antithyroid drugs or radiation exposure during pregnancy may result in reduced synthesis of thyroxine and cause congenital goiter with or without thyroid dysfunction. We report a case of a full term, newborn male baby who had normal thyroid functions but was born with a neck swelling and no apparent abnormalities. Maternal investigations for thyroid function tests were found normal as well.
Bangladesh J. Nuclear Med. 25(2): 121-124, 2022
Rare Presentations of Muscular Infiltrations in Classical Hodgkin’s lymphoma-A Case Series
Authors: Mandal Tapati , Mutsuddy Pupree , Ahmed Mezbah , Nath Khokon Kumar , Siddique Abu Bakker , Begum Shamim MF
Published: July 2023

Hodgkin’s lymphoma (HL) is a malignant condition of the lymphoid system that involves supradiaphragmatic recesses, and typically presents with lymphadenopathy and spreads from one nodal group to the other. Skeletal muscle infiltration in HL is uncommon. Two cases of classical HL evaluated by an 18F-FDG PET-CT scan detecting multiple extranodal metastases along with skeletal muscle involvement are reported here, and their outcomes are discussed along with the importance of the PET-CT scan as a good imaging modality.
Bangladesh J. Nuclear Med. 25(2): 143-146, 2022
Subdiaphragmatic High Renal Ectopia associated with Eventration of the Diaphragm: A Case Report
Authors: Munir Md Sirazul , Bhuiyan Md Mehedi Al Zahid , Nahar Kamrun , Mia Md Azzad
Published: July 2023

Subdiaphragmatic high renal ectopia and eventration of the diaphragm are unusual entities, and the combination of the two is extremely rare. We present a case of a young man with non-visualized left kidney in abdominal ultrasonography (USG). Static renal scan with 99mTc-DMSA showed an abnormally high, relatively smaller, and malrotated left kidney without any renal scarring. CT scan was also done to rule out possible associated abnormalities. It became evident that the left kidney was smaller and malrotated, lying posteriorly and much above the spleen and stomach as well, but immediately beneath the abnormally high left dome of the diaphragm at the level of the sixth rib. Apart from the abnormally high left dome, there were no other abnormalities seen in the diaphragm. The reported case of diaphragmatic eventration with high renal ectopia may be an important differential diagnosis of diaphragmatic rupture, a frequently encountered difficulty in clinical practice.
Bangladesh J. Nuclear Med. 25(2): 151-153, 2022
Angiomyolipoma in the Transplanted Kidney Presenting with Hematuria- Rare Case Report
Authors: Persi Abdullah Al , Bhattacharjee Pabitra Kumar , Muhtasim Muhammad Farhan , Hossain Mohammad Sazzad , Alim Noor e Amrin
Published: July 2023

Renal angiomyolipomas (AML) are a type of benign renal neoplasm composed of vascular, smooth muscle, and fat elements, usually exhibiting characteristic radiographic appearances. Although benign, they carry the risk of spontaneous hemorrhage, which can potentially be fatal. AML has an incidence of 0.3% to 3%, hence reports of this condition are relatively scarce; even more so is the unique presentation of AML in the transplanted kidney. Predictably, there have been few reports of this uncommon condition in the medical literature. Herein, we report a very rare case of an isolated AML in a transplanted kidney that developed more than a decade after uneventful renal transplantation.A 56-year-old female had a kidney transplant in early 2010, but subsequently developed chronic graft rejection. She presented with haematuria, and upon further assessment, a fairly large SOL in the kidney allograft was revealed by imaging including abdominal ultrasound, a 99mTc-DMSA scan, and a CT scan. She had graft nephrectomy in early 2022 and is still on haemodialysis. 
Bangladesh J. Nuclear Med. 25(2): 154-156, 2022
Pengaruh Penggunaan Madu Untuk Pengobatan Akne Vulgaris
Authors: Pasombak Selin Iriana , Yunianti Lisa , Arsal Andi Sitti Fahirah , Julyani Sri , Irmandha Sri
Published: July 2023

Akne vulgaris adalah suatu kondisi dari unit pilosebasea pada kulit yang menyerang sekitar 85% remaja di seluruh dunia. Akne bermanifestasi sebagai papula, pustula, dan nodul biasanya disertai nyeri dan menetap di rahang, dagu, dan leher bagian atas. Terapi yang digunakan untuk pengobatan akne vulgaris adalah antibiotik topical. Madu telah digunakan sebagai pengobatan topikal yang murah dan efektif untuk luka. Sifat antibakteri madu membantu mengatasi infeksi pada luka sedangkan sifat anti inflamasinya dapat mengurangi nyeri yang berpengaruh pada proses penyembuhan. Penelitian ini bertujuan untuk mengetahui Pengaruh Penggunaan Madu Untuk Pengobatan Akne Vulgaris. Metode penelitian ini adalah literatur review dengan desain narrative review. Hasil penelitian didapatkan bahwa madu memiliki pH yang rendah, kandungan glukosa yang tinggi, senyawa fenolik, flavonoid, alkaloid, terpenoid dan saponin yang bermanfaat sebagai antibakteri, antioksidan, antiinflamsi serta antiseptik untuk penyembuhan akne vulgaris. Kesimpulan penelitian ini bahwa madu terbukti dapat digunakan untuk mengobati akne vulgaris pada wajah.
Pengaruh Pemberian Ekstrak Buah Pare Terhadap Penurunan Kadar Glukosa Darah Pada Mencit (Mus musculus)
Authors: Afifah Andi Retno , Wahyu Sri , Gayatri Sri Wahyuni , Daeng Kanang Indah Lestari , Indarwati Abdullah Rezky Putri
Published: July 2023

Diabetes melitus (DM) mengacu pada sindrom hiperglikemia akibat berbagai penyebab. Dewasa ini, banyak masyarakat yang mengkonsumi buah pare sebagai obat diabetes. Karena menurut pemikiran mereka, rasa pahit nya dapat menetralisir kadar gula dalam darah.  Momordica charantia (Buah Pare) adalah tanaman  yang digunakan sebagai sayuran dan obat tradisional dengan aktivitas buah hipoglikemik. Momordica charantia (Buah Pare) mengandung senyawa seperti insulin yang disebut charantin yang memiliki sifat anti diabetes dan membantu mengurangi kadar gula darah. Penelitian ini bertujuan mengetahui pengaruh pemberian ekstrak buah pare (Momordica charantia) terhadap penurunan kadar glukosa darah pada mencit (Mus musculus). Jenis penelitian ini menggunakan Literature Review dengan desain Narrative Review. Ekstrak buah pare (Momordica charantia) dapat menurunkan kadar glukosa darah pada mencit (Mus musculus) diabetes dengan konsentrasi 100 mg/kgBB, 250 mg/kgBB dan 400 mg/kgBB. Ekstrak buah pare  (Momordica charantia) dengan konsentrasi 400 mg/KgBB dapat menurunkan glukosa darah yang hampir setara dengan pemberian metformin pada mencit (Mus musculus) yang diabetes. Ekstrak buah pare (Momordica charantia) dapat menurunkan kadar glukosa darah pada mencit (Mus musculus) diabetes. Namun lebih efektif pada dosis 400 mg/Kg.
Gambaran Pola Tidur Mahasiswa Angkatan 2018
Authors: Apriliah Riskiyanti , Nurmadilla Nesyana , Pratiwi. LB Rezky , Mokhtar Shulhana , Arifin Arina Fathiyyah
Published: July 2023

Tidur adalah aspek kehidupan yang penting yang terjadi secara berulang. Mahasiswa kedokteran memiliki jadwal padat yang berpotensi berkontribusi pada kualitas tidur yang buruk. Kualitas tidur yang buruk di antara mahasiswa kedokteran biasanya bermanifestasi sebagai kantuk di siang hari yang berlebihan. Mahasiswa kedokteran di Amerika Serikat tahun 2014 yang menunjukkan gangguan tidur pada mahasiswa kedokteran sekitar 50%. Penelitian ini bertujuan untuk Mengetahui gambaran pola tidur mahasiswa Fakultas Kedokteran Universitas Muslim Indonesia angkatan 2018. Penelitian ini merupakan penelitian deskriptif dengan pendekatan cross sectional dengan media survei menggunakan Kuesioner The Pittsburgh Sleep Quality Index (PSQI). Pada penelitian ini didapatkan durasi tidur mahasiswa FK UMI Angkatan 2018 yaitu sebanyak 21 orang (9,1%) memiliki durasi tidur > 7 jam per malam, 54 orang (23,4%) dengan durasi 6-7 jam per malam, 131 orang (56,7%) dengan durasi 5-6 jam per malam  dan 25 orang (10,8%) dengan durasi < 5 jam per malamnya. Sedangkan sebanyak 78 orang mahasiswa (33,8%) memiliki kualitas tidur yang baik dan sebanyak 153 orang mahasiswa (66,2%) memiliki kualitas tidur yang buruk.. Kesimpulan pada penelitian ini rata-rata durasi tidur pada mahasiswa FK UMI angkatan 2018 adalah 5 sampai 6 jam. Sebanyak 153 (66.2%) mahasiswa FK UMI angkatan 2018 dikategorikan memiliki kualitas tidur yang buruk
Performance Analysis of Scheduling Algorithms on Fog Computing using YAFS
Authors: Nurcahya Dimas , Karimah Siti Amatullah , Mugitama Satria Akbar
Published: July 2023

A smart device that has seen more development is the Internet of Things (IoT). An IoT system implementation requires a device that can accept and handle various sorts of data. Fog Computing is a solution to the issue since the IoT demands a device that can provide Real-Time. Certainly, load balancing involves scheduling the IoT devices and data used. Because Cloud and Fog Computing models enable data growth management and deployment planning, which necessitate a quicker response from platforms and applications, processing power scheduling is essential. The purpose of this study is to evaluate the performance of effective scheduling algorithms that adhere to these computing models platform requirements. The scheduling algorithm that can produce the lowest Processing Time and the resulting Time Efficiency is more efficient can be called the best scheduling algorithm. In this research, the author analyzes the performance of scheduling algorithms in the form of Round Robin and Priority Scheduling on Fog Computing. In this research, testing was carried out by creating a scenario of the effect of increasing the number of Fog Nodes and Devices used. The average result of scenario testing obtained for processing time for Round Robin is lower, and the highest Time Efficiency for Round Robin over Priority Scheduling is 11%. With these test results, the Round Robin scheduling algorithm has a simpler level of complexity. So, it can be concluded that Round Robin belongs to the category of the best scheduling algorithm in this case.
Human resources development strategy use Backpropagation Artificial Neural Networks
Authors: Panggabean Erwin , Sitio Arjon Samuel , Lase Yulianto , Junita Diana
Published: July 2023

The strategy for developing human resources for recruitment so that at the same time becoming a reliable workforce as expected is the goal of personnel in certain offices or agencies. This step must be taken by the management of companies or institutions, both public and private, in order to improve human resources (HR). Until now, there has never been any research on the conventional acceptance of prospective employees to test how accurate their performance is. In this study the conventional selection system for prospective employees will be used as a basic concept to find methods for analyzing the performance of prospective employees using computer media with an artificial neural network system approach with the backpropagation method. So that the accuracy of the predictive patterns of prospective new employees is obtained. So that finally the personnel of government and private agencies obtain actual information about the performance of prospective employees who will be accepted as workers. The results of the study using hidden layers and learning constants obtained the fastest convergent value at 3377, and the final results of this study will be published in a national journal accredited SINTA 4 or better.
Single Lymph Node Metastasis and Adjuvant Therapy in Stage III Tongue Cancer
Authors: Lee Han Cheol , Lim Jae-Yol , Koh Yoon Woo , Kim Se-Heon , Choi Eun Chang , Park Young Min
Published: July 2023

Background and Objectives We analyzed treatment results among stage III oral tongue squamous cell carcinoma (OTSCC) patients and performed subgroup analyses according to the depth of invasion (DOI) and node positivity.Subjects and Method We retrospectively analyzed the medical records of 87 stage III OTSCC patients.Results A total of 32 recurrences occurred during the study period, eight cases of local recurrence, 12 cases of regional recurrence, eight cases of distant metastasis, and four cases of loco-regional recurrence. During the study period, 27 patients died due to disease progression. The 5-year recurrence-free survival of the patients was 62.9%, and the 5-year disease-specific survival (DSS) was 75.3%. When prognostic factors related to disease recurrence and survival were analyzed through univariate and multivariate analyses, only the N classification was significantly associated with patient survival (hazard ratio 0.36, confidence interval 0.14-0.91). The 5-year DSS of N0 patients was 87.6%, and the 5-year DSS of N1 patients was 63.9%. Among N1 patients, the 5-year DSS was 90.5% when adjuvant therapy was administered and 63.9% when adjuvant therapy was not administered, which is a statistically significant difference. We did not observe any difference in treatment outcome or survival between patients with superficial (DOI ≤10 mm) or deep lesions (DOI >10 mm).Conclusion Among the stage III OTSCC patients, patients with single lymph node (LN) metastasis (N1) showed a distinct prognostic difference from other patients (N0), and the administration of adjuvant therapy to patients having single LN metastasis without other risk factors significantly improved their 5-year DSS.
BUILDING MULTICULTURAL CHARACTERS BASED ON PESANTREN VALUES
Authors: Salam Miftahus
Published: July 2023

Pesantren has long historical source in Indonesia as an educational institution. The adaptive nature of Pesantren and accepting students from various realities leading up to be one of education icon. Pesantren Al Hasani Al Latifi, which is more familiarly known as Pesantren Kauman Bondowoso, is an Islamic boarding school with a multicultural character. The multicultural reality at the Kauman Islamic Boarding School are carried out internally for Pesantren residents, as well as for the people of Kauman Village in general. This article intends to discuss the problem of building a multicultural character based on the values of the Pesantren in Kauman Islamic boarding school Bondowoso. This research is qualitative and the type of case study because of the characteristics and paradigm of Kauman Islamic Boarding School. Researcher as instruments as well as data collectors will carry out observations, interviews, and document retrieval. Data obtained in three ways, namely interviews, observation, and documentation. Data analysis in this study, data analysis was carried out since data collection as a whole and was checked over. The results of the study state a multicultural character with four indicators, that is tolerance, democracy, equality, and justice, reinforced by the values of the Pesantren, Pancabakti. It contains devotion to Allah and His Messenger, Devotion to Religion, Devotion to Teachers, Devotion to Parents, Devotion to Society, Nation, and State. The multicultural character is in synergy with the Pesantren Pancabakti is the main asset in building a space for students' awareness of multicultural characters. Second, understanding the multicultural character means strengthening the emotional sensitivity of Santri regarding indicators of multicultural character and also Islamic boarding school service. Indicators of multicultural character in Kauman Islamic Boarding School, which are synergized with the Islamic Boarding School Pancabakti, make the spectrum of multicultural characters broader and have a religious dimension. Third, multicultural character-based actions carried out by caregivers and Ustadz, are efforts to combine the areas of awareness and understanding of the Santri to accustom students to acting according to multicultural characters. Building multicultural character-based attitude action is given by exemplary in the form of mutual respect, mutual respect, and giving the same treatment regardless of the background of the students.
THE IMPLEMENTATION OF MULTICULTURAL ISLAMIC EDUCATION VALUES AT TENGGER COMMUNITY LOCAL CULTURE (An Ethnographic Study in Sapikerep Village, Sukapura, Probolinggo)
Authors: Ubaidillah Ubaidillah
Published: July 2023

This article investigates the implementation of multicultural Islamic education that exists amongst Tengger tribe kwown as indigenous community living in Sapikerep Village, Sukapura, Probolinggo Regency, East-Java. The purposes of this article are; first, describe, analyze and interpret the values of multicultural Islamic education contained in the local culture, second, describe, analyze and interpret the application of multicultural Islamic educational values in the local culture of the Tengger people in Sapikerep Village, Sukapura, Probolinggo Regency. This research is a type of qualitative research with Cresswell's realist ethnographic approach. Data collection techniques use participant observation techniques, in-depth interviews, and documentation. While informant determination use purposive and snowball sampling techniques. As for analyzing data use spreadly analysis techniques, which perform analysis with four steps, namely domain analysis, taxonomic analysis, component analysis, and cultural theme analysis. The continuation of data validity test techniques using source trianggulation techniques, methods, and theories. The results of this study show there are values of Multicultural Islamic education tengger culture in Sapikerep in the form of respect, mutual advice, help each other and Â conserve nature/environment. These values are implemented in tengger ceremonies, such as Kasada ceremonies, Karo ceremonies, Unan-Unan and others. By the end, formed the implementation of multicultural Islamic educational values to the local culture of the Tengger tribe in the form of AGIL -based assimilation models (adaptation, goal attainment, integrating, and latency).Keywords:Â  Values of Multicultural Islamic Education, Tengger local culture
THE CONSTITUTIONAL APPROACH AND HISTORY OF ISLAMIC POLITICAL TO VIOLATIONS OF THE RIGHTS TO RELIGIOUS FREEDOM IN INDONESIA
Authors: Hufron Hufron , Wahid Abdul , Syaifuddin Mohammad
Published: July 2023

Religious freedom in Indonesia has not been fully respected by every party. There are still a number of parties who address or treat adherents of other religions as individuals or religious groups that deserve to be disturbed in harmony and even if necessary do not have a place to carry out their religious activities. The attitude and behavior of those who are intolerant of disharmony are unconstitutional, which in the study of the history of religious politics in Islam is also contradictory. This unconstitutionality cannot be separated from his feelings and beliefs, which puts parties outside of himself as a lost party or groupKeywords:Â  history, politics. constitution, freedom, religion
ANALISIS ELEMEN IMAGE OF THE CITY DI KOTA MALANG
Authors: Mubarok Jalaluddin
Published: July 2023

Perkembangan perkotaan pada suatu daerah pasti mengalami kemajuan seiring berjalannya peradaban manusia, sehingga pada umumnya perkembangan perkotaan tidak hanya berkembang secara kuantitas atau jumlah penduduk, melainkan juga dari segi perkembangan seni arsitektur, elemen-elemen arsitektur lainnya. Hal ini membuat peneliti merasa penting dalam hal mengkaji dan menganalisa terkait perkembangan perkotaan khususnya pada perkembangan perkotaan menurut teori dari Kevin Lynch yakni Image of the City. Hal ini dilihat dari perkembangannya pasti sudah sangat berbeda dengan teori dan penerapan di perkotaan dan kawasan suatu kota di wilayah tertentu. Hal ini juga mendorong peneliti untuk memetakan terhadap kawasan salah satu perkotaan yang ada di Jawa Timur, yakni kota Malang. Dikarenakan lokasi tersebut berada pada area yang mengalami pertumbuhan dan perkembangan yang sangat pesat, sehingga perlu adanya pengkajian dan pemetaan terhadap elemen-elemen perkotaan yang ada di kota Malang tersebut. Sehingga output yang akan diambil dari penelitian ini adalah sebuah layout kawasan perkotaan kota Malang dan detail elemen Image of the City.
Pemberdayaan Nelayan Wilayah Pesisir Oleh Pemerintah Desa Banjar Kemuning Kecamatan Sedati Kabupaten Sidoarjo
Authors: Uswatun Chasanah  , Prathama Ananta
Published: July 2023

Kondisi sebagai negara maritim menyebabkan Indonesia sangat bergantung pada sumber daya laut untuk makanan, mata pencaharian, dan nilai-nilai budaya. Sebagian besar masyarakat, terutama yang berada di pesisir memilih profesi sebagai nelayan untuk mata pencaharian. Namun, kesejahteraan nelayan kurang mendapat perhatian yang maksimal dari pemerintah salah satunya para nelayan yang ada di Desa Banjar Kemuning Kecamatan Sedati Kabupaten Sidoarjo. Penelitian ini bertujuan untuk mengetahui pemberdayaan nelayan wilayah pesisir oleh Pemerintah Desa Banjar Kemuning Kecamatan Sedati Kabupaten Sidoarjo. Metode penelitian yang digunakan pada penelitian ini yaitu deskriptif kualitatif dengan teknik pengumpulan data berupa wawancara, dokumentasi dan observasi. Fokus penelitian pada penelitian ini menggunakan menggunakan 4 (empat) dari 6 (enam) konsep menurut teori Mardikanto (2014). Hasil penelitian menunjukkan bahwa: 1) Perbaikan kelembagaan yang dilakukan Pemerintah Desa Banjar Kemuning yaitu membangun kembali KUB, mengembangkan jejaring kemitraan usaha, dan menjadi penghubung antara nelayan dan dinas untuk mendapatkan bantuan modal. 2) Perbaikan usaha yang dilakukan Pemerintah Desa Banjar Kemuning yakni membentuk unit usaha baru di KUB yaitu budidaya ikan udang Vannamei, akan tetapi dalam kegiatan ini partisipasi nelayan masih kurang. 3) Perbaikan pendapatan yang dilakukan yaitu hanya sebatas membantu untuk menjadi jembatan agar nelayan mendapat bantuan dan pinjaman modal. 4) Perbaikan Lingkungan yang dilakukan yaitu membentuk “Rumah Desa Sehat, namun belum maksimal dalam perbaikan lingkungan fisik karena pembuangan limbah kulit kerang dan tempat pengupasan kerang belum diperbaiki secara layak dan memadai.
PERBANDINGAN KESEJAHTERAAN MILENIAL SEBELUM DAN SAAT PANDEMI COVID-19 DI KOTA MAKASSAR.
Authors: Mutahar Farhan , AT M. Ramli , Raf Nuvida
Published: July 2023

Pandemi Covid-19 terbukti mempengaruhi banyak dimensi kehidupan yang merupakan bagian dari kesejahteraan. Penelitian ini bertujuan untuk mengungkap, mendeskripsikan, dan membandingkan kesejahteraan milenial sebelum dan selama pandemi di Kota Makassar, dilihat dari perspektif objektif dan subjektif. Penelitian ini menggunakan teknik purposive sampling yang melibatkan 350 partisipan. Karakteristik responden adalah usia 25-39 tahun, bekerja sebelum atau selama pandemi dan bertempat tinggal atau berdomisili di Kecamatan Rappocini, Kota Makassar. Hasil penelitian ini menunjukkan bahwa untuk kesejahteraan objektif, frekuensi jawaban tertinggi indikator pendapatan, pengeluaran untuk sandang, pangan, dan hiburan dalam sebulan mengalami penurunan sebesar 4%, 6,3%, 9,1% dan 5,2% selama pandemi, tetapi pengeluaran untuk kesehatan dan internet dan komunikasi dalam sebulan meningkat sebesar 0,9% dan 0,6%. Hasil untuk kesejahteraan subjektif, frekuensi pada kategori jawaban tertinggi mengalami penurunan untuk setiap indikator. Indikator bahagia dalam hidup, bahagia dalam bekerja dan puas dengan kemampuan memenuhi kebutuhan menunjukkan penurunan yang cukup signifikan, yakni sebesar 11,5%, 6,3%, 8,5%. Indikator lain yang menunjukkan penurunan yang lebih tipis adalah puas dengan kondisi kesehatan, puas dengan kehidupan sosial dan kemudahan dalam mengambil keputusan sebesar 2,6%, 7,2% dan 4%.
Koordinasi Komisi Penanggulangan AIDS dalam Upaya Pencegahan Penularan HIV/AIDS di Kota Sorong
Authors: Kelibay Ismed , Abdul Kadir Muhammad Arifin , Nikmatul Ula Siti Nurul , Basri La , Rosnani Rosnani
Published: July 2023

Tujuan penelitian ini adalah untuk mengetahui sejauhmana koordinasi komisi penanggulangan AIDS dalam upaya pencegahan penularan HIV/AIDS di Kota Sorong Provinsi Papua Barat Daya. Koordinasi memegang peranan yang sangat penting bagi tercapainya tujuan yang telah ditetapkan. Tanpa adanya koordinasi maka dapat dipastikan suatu program yang telah direncanakan tidak dapat berjalan secara optimal. Metode yang digunakan adalah penelitian kualitatif dengan mengunakan teknik observasi, wawancara, dan dokumentasi, sehingga mendapatkan data yang mendalam. Hasil penelitian yang dilakukan menunjunkkan bahwa, kelompok instansi terkait yang seharusnya menjadi pemberi pesan kepada masyarakat tidak berjalan dengan baik sehingga angka penderita HIV dan AIDS dari kelompok masyarkat umum terus bertambah. Selain itu, Kualitas Sumber Daya Manusia yang ada pada KPA Kota Sorong yang belum memadai, kurangnya rapat koordinasi serta ketidakmampuan pemerintah daerah dalam pelaksanaan program-program terkait penanggulangan AIDS di Kota Sorong. Sehingga dapat disimpulkan bahwa pelaksanaan koordinasi yang dilakukan oleh KPA Kota Sorong bersama instansi, maupun lembaga-lembaga terkait belum optimal terlaksanan dengan baik. Oleh sebab itu, diharapkan agar pimpinan KPA yakni Wali Kota Sorong harus lebih banyak melibatkan instansi dan lembaga-lembaga terkait lainnya guna penyebaran informasi kepada masyarakat serta turut aktif dalam memonitor jalanya koordinasi kepada seluruh anggota KPA Kota Sorong, dengan begitu maka penanggulangan HIV dan AIDS di Kota Sorong akan meningkat lebih baik lagi
Influence of seagrass on juvenile Pacific oyster growth in two US west coast estuaries with different environmental gradients
Authors: Dumbauld B , McIntyre B
Published: July 2023

Ocean acidification threatens many marine organisms, including oysters. Seagrass habitat has been suggested as a potential refuge for oysters because it may ameliorate stressful carbonate chemistry and augment food availability. We conducted an in situ study to investigate whether eelgrass Zostera marina habitat affects the growth of juvenile Pacific oysters Crassostrea gigas and influences local carbonate chemistry or food quantity at sites where we expected contrasting conditions in two US west coast estuaries. Juvenile oysters were out-planted in typical intertidal on-bottom (just above sediment) and off-bottom (45 cm above sediment) culture positions and in adjacent eelgrass and unvegetated habitats from June to September 2019. Water quality was measured with sondes for 24 h periods each month, and discrete water samples were collected in conjuncture. Results show that eelgrass habitat did not alter average local carbonate chemistry (pH, pCO2, Ωcalcite), but consistently reduced available food (relative chlorophyll a). Eelgrass habitat had little to no effect on the shell or tissue growth of juvenile oysters but may have influenced their energy allocation; oysters displayed a 16% higher ratio of shell to tissue growth in eelgrass compared to unvegetated habitat when cultured on-bottom. At the seascape scale, average site-level pH was negatively correlated with shell to tissue growth but not with shell growth alone. Overall, these findings suggest that juvenile oysters may display a compensatory response and allocate more energy to shell than tissue growth under stressful conditions like acidic water and/or altered food supply due to reduced immersion or eelgrass presence.
A newly isolated cotton-infecting Polerovirus with cryptic pathogenicity encodes a weak suppressor of RNA silencing
Authors: Akinyuwa Mary F. , Price Bailee K. , Martin Kathleen M. , Kang Sung-Hwan
Published: July 2023

Cotton is a multipurpose crop grown globally, including the United States. Cotton leafroll dwarf virus (CLRDV), a phloem-limited virus (Solemoviridae) transmitted by aphids, causes significant economic losses to cotton cultivation. CLRDV strains (CLRDV-typical and atypical) that were previously prevalent in other countries cause severe symptoms leading to high yield loss. Recently, a new isolate of CLRDV (CLRDV-AL) has been characterized from infected cotton plants in Alabama that are often asymptomatic and difficult to detect, implying a low titer and pathogenicity within the host. Different pathogenicity among certain strains within the same species often correlates with both environmental and molecular factors. Thus, better management and control of the vector-borne disease can be achieved by elucidating host-pathogen interaction, such as host immune response and pathogen counter-response. In this study, we demonstrate the ability of CLRDV-AL to suppress a major host defense response known as RNA silencing and compare the potency of silencing suppression to other strains of the same virus. Also, we discuss the difference in pathogenicity among them by evaluating the observations based on the amino acid variation within the functional domain. Our study provides and suggests a future direction for specifying the strategy to mitigate potential cotton disease severity.
Role of TNF-α-induced m6A RNA methylation in diseases: a comprehensive review
Authors: Wang Youlin , Liu Jing , Wang Yongchen
Published: July 2023

Tumor Necrosis Factor-alpha (TNF-α) is ubiquitous in the human body and plays a significant role in various physiological and pathological processes. However, TNF-α-induced diseases remain poorly understood with limited efficacy due to the intricate nature of their mechanisms. N6-methyladenosine (m6A) methylation, a prevalent type of epigenetic modification of mRNA, primarily occurs at the post-transcriptional level and is involved in intranuclear and extranuclear mRNA metabolism. Evidence suggests that m6A methylation participates in TNF-α-induced diseases and signaling pathways associated with TNF-α. This review summarizes the involvement of TNF-α and m6A methylation regulators in various diseases, investigates the impact of m6A methylation on TNF-α-induced diseases, and puts forth potential therapeutic targets for treating TNF-α-induced diseases.
Comparing the clinical outcomes of single vs. systematic dual stenting strategies for unprotected left main bifurcation lesion: a systematic review and meta-analysis
Authors: Meng Shuai , Kong Xiangyun , Nan Jing , Yang Xingsheng , Li Jianan , Yang Shenghua , Zhao Lihan , Jin Zening
Published: July 2023

Introduction

The optimal percutaneous coronary intervention (PCI) strategy for coronary left main (LM) bifurcation lesions remains controversial. This meta-analysis compared the medium and long-term follow-up clinical outcomes of single vs. systematic dual stenting strategies of LM bifurcation lesions.

Methods

We systematically identified studies published within 5 years comparing single vs. systematic double stenting strategies for LM bifurcation lesions. The primary endpoint was medium-term (1 year) and long-term (at least 3 years) all-cause death. Secondary outcomes included major adverse cardiovascular events (MACEs), target lesion revascularization (TLR), overall occurrence of stent thrombosis (ST), cardiovascular (CV) mortality, and myocardial infarction (MI).

Results

Two randomized controlled trials and nine observational studies with 7,318 patients were included in this meta-analysis. In terms of the medium-term follow-up clinical outcomes, our pooled analysis showed that use of the systematic dual stenting strategy was associated with a lower ST risk (odds ratio [OR] = 0.43, 95% confidence interval [CI]: 0.20–0.89,P = 0.02) and cardiac death risk (OR = 0.43, 95% CI: 0.21–0.89,P = 0.02) compared to the single stenting strategy; there was no significant difference between the two strategies regarding rates of all-cause death, MACE, TLR, and MI. Patients with long-term follow-up showed comparable observed clinical outcomes between the two strategies. Most importantly, for patients with true LM bifurcation, the risk of all-cause death, ST, and CV mortality following the systematic dual stenting strategy was significantly lower than the single stenting strategy.

Conclusions

For patients with LM bifurcation lesions, both the systematic dual stenting strategy and single stenting strategy demonstrated comparable results in terms of all-cause mortality during medium-term and long-term follow-up. However, the systematic dual stenting strategy showed a tendency towards lower incidence of ST and CV mortality compared to the single stenting strategy during medium-term follow-up. Consequently, the systematic dual stenting strategy yielded superior clinical outcomes for patients with LM bifurcation lesions.