bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 3 from OTX2 Represses Myogenic and Neuronal Differentiation in Medulloblastoma Cells
Authors: Bai Ren-Yuan , Staedtke Verena , Lidov Hart G. , Eberhart Charles G. , Riggins Gregory J.
Published: March 2023

PDF file, 51 K, No protein-protein interaction between OTX2 and MyoD.
Supplementary Figure 2 from OTX2 Represses Myogenic and Neuronal Differentiation in Medulloblastoma Cells
Authors: Bai Ren-Yuan , Staedtke Verena , Lidov Hart G. , Eberhart Charles G. , Riggins Gregory J.
Published: March 2023

PDF file, 111K, Differentiation induced by OTX2 knockdown in D425, D458 and D341 cells.
Supplementary Data Legends from OTX2 Represses Myogenic and Neuronal Differentiation in Medulloblastoma Cells
Authors: Bai Ren-Yuan , Staedtke Verena , Lidov Hart G. , Eberhart Charles G. , Riggins Gregory J.
Published: March 2023

PDF file, 90K
Supplementary Table 8 from Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors
Authors: Niinuma Takeshi , Suzuki Hiromu , Nojima Masanori , Nosho Katsuhiko , Yamamoto Hiroyuki , Takamaru Hiroyuki , Yamamoto Eiichiro , Maruyama Reo , Nobuoka Takayuki , Miyazaki Yasuaki , Nishida Toshirou , Bamba Takeo , Kanda Tatsuo , Ajioka Yoichi , Taguchi Takahiro , Okahara Satoshi , Takahashi Hiroaki , Nishida Yasunori , Hosokawa Masao , Hasegawa Tadashi , Tokino Takashi , Hirata Koichi , Imai Kohzoh , Toyota Minoru , Shinomura Yasuhisa
Published: March 2023

XLS file - 47K, Predicted miR-196a target genes whose expression was reduced in GISTs overexpressing miR-196a
Supplementary Table 3 from Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors
Authors: Niinuma Takeshi , Suzuki Hiromu , Nojima Masanori , Nosho Katsuhiko , Yamamoto Hiroyuki , Takamaru Hiroyuki , Yamamoto Eiichiro , Maruyama Reo , Nobuoka Takayuki , Miyazaki Yasuaki , Nishida Toshirou , Bamba Takeo , Kanda Tatsuo , Ajioka Yoichi , Taguchi Takahiro , Okahara Satoshi , Takahashi Hiroaki , Nishida Yasunori , Hosokawa Masao , Hasegawa Tadashi , Tokino Takashi , Hirata Koichi , Imai Kohzoh , Toyota Minoru , Shinomura Yasuhisa
Published: March 2023

XLS file - 28K, Correlation between miR-196a expression and the GIST risk category
Supplementary Table 2 from Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors
Authors: Niinuma Takeshi , Suzuki Hiromu , Nojima Masanori , Nosho Katsuhiko , Yamamoto Hiroyuki , Takamaru Hiroyuki , Yamamoto Eiichiro , Maruyama Reo , Nobuoka Takayuki , Miyazaki Yasuaki , Nishida Toshirou , Bamba Takeo , Kanda Tatsuo , Ajioka Yoichi , Taguchi Takahiro , Okahara Satoshi , Takahashi Hiroaki , Nishida Yasunori , Hosokawa Masao , Hasegawa Tadashi , Tokino Takashi , Hirata Koichi , Imai Kohzoh , Toyota Minoru , Shinomura Yasuhisa
Published: March 2023

XLS file - 31K, Summary of miR-196a expression results in each GIST risk category
Supplementary Table 10 from Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors
Authors: Niinuma Takeshi , Suzuki Hiromu , Nojima Masanori , Nosho Katsuhiko , Yamamoto Hiroyuki , Takamaru Hiroyuki , Yamamoto Eiichiro , Maruyama Reo , Nobuoka Takayuki , Miyazaki Yasuaki , Nishida Toshirou , Bamba Takeo , Kanda Tatsuo , Ajioka Yoichi , Taguchi Takahiro , Okahara Satoshi , Takahashi Hiroaki , Nishida Yasunori , Hosokawa Masao , Hasegawa Tadashi , Tokino Takashi , Hirata Koichi , Imai Kohzoh , Toyota Minoru , Shinomura Yasuhisa
Published: March 2023

XLS file - 33K, Predicted miR-196a target genes whose expression was upregulated by an anti-miR-196a inhibitor in GIST-T1 cells
Supplementary Figure 1 from Rat Mcs1b Is Concordant to the Genome-Wide Association-Identified Breast Cancer Risk Locus at Human 5q11.2 and MIER3 is a Candidate Cancer Susceptibility Gene
Authors: denDekker Aaron D. , Xu Xin , Vaughn M. Derek , Puckett Aaron H. , Gardner Louis L. , Lambring Courtney J. , Deschenes Lucas , Samuelson David J.
Published: March 2023

PDF file - 43K, C5ORF35 RT-PCR and lack of conservation
Supplementary Figures 1-3 from PRAS40 Is a Functionally Critical Target for EWS Repression in Ewing Sarcoma
Authors: Huang Lin , Nakai Yuji , Kuwahara Iku , Matsumoto Ken
Published: March 2023

PDF file - 111K
Supplementary Methods from Integrative Genomic Analyses of Sporadic Clear Cell Renal Cell Carcinoma Define Disease Subtypes and Potential New Therapeutic Targets
Authors: Dondeti Vijay R. , Wubbenhorst Bradley , Lal Priti , Gordan John D. , D'Andrea Kurt , Attiyeh Edward F. , Simon M. Celeste , Nathanson Katherine L.
Published: March 2023

PDF file - 29K
Supplementary Figure 4 from Glucose-Regulated Protein 78 Controls Cross-talk between Apoptosis and Autophagy to Determine Antiestrogen Responsiveness
Authors: Cook Katherine L. , Shajahan Ayesha N. , Wärri Anni , Jin Lu , Hilakivi-Clarke Leena A. , Clarke Robert
Published: March 2023

PDF file - 388K, GRP78 promotes survival signaling schematic
Supplementary Figure 1 from MiR-10b Downregulates the Stress-Induced Cell Surface Molecule MICB, a Critical Ligand for Cancer Cell Recognition by Natural Killer Cells
Authors: Tsukerman Pinchas , Stern-Ginossar Noam , Gur Chamutal , Glasner Ariella , Nachmani Daphna , Bauman Yoav , Yamin Rachel , Vitenshtein Alon , Stanietsky Noah , Bar-Mag Tomer , Lankry Dikla , Mandelboim Ofer
Published: March 2023

PDF file - 328K, TargetScan predictions
Supplementary Figures 1-2 from CXCL10 Promotes Osteolytic Bone Metastasis by Enhancing Cancer Outgrowth and Osteoclastogenesis
Authors: Lee Jong-Ho , Kim Ha-Neui , Kim Kyung-Ok , Jin Won Jong , Lee Seungbok , Kim Hong-Hee , Ha Hyunil , Lee Zang Hee
Published: March 2023

PDF file - 256K, Figure S1. Effects of aCXCL10 on tumor metastasis into lungs and adrenal glands. Figure S2. CXCL10-induced adhesion and survival of B16F10 cells
Supplementary Methods from Temporary Disruption of the Blood–Brain Barrier by Use of Ultrasound and Microbubbles: Safety and Efficacy Evaluation in Rhesus Macaques
Authors: McDannold Nathan , Arvanitis Costas D. , Vykhodtseva Natalia , Livingstone Margaret S.
Published: March 2023

PDF file - 75K, Supplementary Methods including focused ultrasound system calibration, USCA infusion protocol and MRI sequences
Supplemental Materials and Methods from Chemotherapeutic Sensitivity of Testicular Germ Cell Tumors Under Hypoxic Conditions Is Negatively Regulated by SENP1-Controlled Sumoylation of OCT4
Authors: Wu Yu-Chih , Ling Thai-Yen , Lu Shing-Hwa , Kuo Hung-Chih , Ho Hong-Nerng , Yeh Shauh-Der , Shen Chia-Ning , Huang Yen-Hua
Published: March 2023

Supplemental Materials and Methods
Supplementary Figure 2 from Temporary Disruption of the Blood–Brain Barrier by Use of Ultrasound and Microbubbles: Safety and Efficacy Evaluation in Rhesus Macaques
Authors: McDannold Nathan , Arvanitis Costas D. , Vykhodtseva Natalia , Livingstone Margaret S.
Published: March 2023

PDF file - 349K, Figure S2: Histology after volumetric sonication in the hippocampus/LGN in monkey 4. This target was sonicated ~2h before the animal was sacrificed and in seven prior sessions over several months. (A) Contrast-enhanced T1-weighted MRI showing BBB disruption. The region with contrast enhancement is indicated (red dotted line). Inset: Low-magnification microphotograph showing histology in the hippocampus/LGN. The approximate location of this section is indicated in the MR image by the white rectangle. (B) Low- and (C) high-magnification views of the LGN showing normal cell layers and undamaged nerve fibers, respectively. (D) Low and (E) high-magnification views showing normal-appearing granular cell layer of hippocampus. (F): Small capillaries in the LGN found with a few extravasated red blood cells, presumably from the last sonication session. Only a very small number of such extravasations were found. (B, F: H&E; C: H&E-LFB D, E: Nissl; scale bars: A: 1 cm, B, D: 1 mm, C,E-F: 200 Mum)
Supplementary Table 6 from Genetic Variants in miRNAs Predict Bladder Cancer Risk and Recurrence
Authors: Wang Meilin , Chu Haiyan , Li Pu , Yuan Lin , Fu Guangbo , Ma Lan , Shi Danni , Zhong Dongyan , Tong Na , Qin Chao , Yin Changjun , Zhang Zhengdong
Published: March 2023

PDF file, 21K, Primers and probes for genotype screening by TaqMan allelic discrimination.
Supplementary Figure Legends 1-4 from Real-time Raman Spectroscopy for In Vivo Skin Cancer Diagnosis
Authors: Lui Harvey , Zhao Jianhua , McLean David , Zeng Haishan
Published: March 2023

PDF file - 61K
Supplementary Figure 5 from Genetic Variants in miRNAs Predict Bladder Cancer Risk and Recurrence
Authors: Wang Meilin , Chu Haiyan , Li Pu , Yuan Lin , Fu Guangbo , Ma Lan , Shi Danni , Zhong Dongyan , Tong Na , Qin Chao , Yin Changjun , Zhang Zhengdong
Published: March 2023

PDF file, 44K, The position of rs2910164 in the miRNA-146a. Sequences for mature miRNA are shown in red, and the position of the SNP in the miRNA is underlined.
Supplementary Figure 1 from Real-time Raman Spectroscopy for In Vivo Skin Cancer Diagnosis
Authors: Lui Harvey , Zhao Jianhua , McLean David , Zeng Haishan
Published: March 2023

PDF file - 37K, ROC curve for discriminating melanoma (n = 31) from benign pigmented skin lesions (n = 89) for lesions on the head and neck regions only.
Supplementary Table 1 from Stat3 Activation in Urothelial Stem Cells Leads to Direct Progression to Invasive Bladder Cancer
Authors: Ho Philip Levy , Lay Erica Julianne , Jian Weiguo , Parra Diana , Chan Keith Syson
Published: March 2023

PDF file - 47K
Supplementary Figure 4 from Stat3 Activation in Urothelial Stem Cells Leads to Direct Progression to Invasive Bladder Cancer
Authors: Ho Philip Levy , Lay Erica Julianne , Jian Weiguo , Parra Diana , Chan Keith Syson
Published: March 2023

PDF file - 43K, Graphs showing overexpressed Stat3 in MB49 cells has enhanced sphere formation.
Supplementary Figures 1-5, Tables 1-2 from Contrasting Behavior of the p18INK4c and p16INK4a Tumor Suppressors in Both Replicative and Oncogene-Induced Senescence
Authors: Gagrica Sladjana , Brookes Sharon , Anderton Emma , Rowe Janice , Peters Gordon
Published: March 2023

PDF file - 3.4MB
Supplementary Figure 1 from Stat3 Activation in Urothelial Stem Cells Leads to Direct Progression to Invasive Bladder Cancer
Authors: Ho Philip Levy , Lay Erica Julianne , Jian Weiguo , Parra Diana , Chan Keith Syson
Published: March 2023

PDF file - 128K, Figure showing schematics of K5.Stat3C construct and urothelial specific expression of nuclear Stat3.
Supplementary Table 2 from The Human TLR Innate Immune Gene Family Is Differentially Influenced by DNA Stress and p53 Status in Cancer Cells
Authors: Shatz Maria , Menendez Daniel , Resnick Michael A.
Published: March 2023

PDF file - 56K, Genotoxic stress and p53 activation differentially affect expression of TLR1-10 genes across a variety of cancer cell lines
Supplementary Figure 3 from The Human TLR Innate Immune Gene Family Is Differentially Influenced by DNA Stress and p53 Status in Cancer Cells
Authors: Shatz Maria , Menendez Daniel , Resnick Michael A.
Published: March 2023

PDF file - 54K, Role of p53 in ionizing radiation-induced up-regulation of TLRs in MCF7 cells
Supplementary Table 4 from A Combined Array-Based Comparative Genomic Hybridization and Functional Library Screening Approach Identifies mir-30d As an Oncomir in Cancer
Authors: Li Ning , Kaur Sippy , Greshock Joel , Lassus Heini , Zhong Xiaomin , Wang Yanling , Leminen Arto , Shao Zhongjun , Hu Xiaowen , Liang Shun , Katsaros Dionyssios , Huang Qihong , Bützow Ralf , Weber Barbara L. , Coukos George , Zhang Lin
Published: March 2023

PDF file - 118K
Supplementary Figure Legends 1-3 from A Combined Array-Based Comparative Genomic Hybridization and Functional Library Screening Approach Identifies mir-30d As an Oncomir in Cancer
Authors: Li Ning , Kaur Sippy , Greshock Joel , Lassus Heini , Zhong Xiaomin , Wang Yanling , Leminen Arto , Shao Zhongjun , Hu Xiaowen , Liang Shun , Katsaros Dionyssios , Huang Qihong , Bützow Ralf , Weber Barbara L. , Coukos George , Zhang Lin
Published: March 2023

PDF file - 69K
Supplementary Tables 1-2, Figures 1-11 from Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape
Authors: Woo Seng-Ryong , Turnis Meghan E. , Goldberg Monica V. , Bankoti Jaishree , Selby Mark , Nirschl Christopher J. , Bettini Matthew L. , Gravano David M. , Vogel Peter , Liu Chih Long , Tangsombatvisit Stephanie , Grosso Joseph F. , Netto George , Smeltzer Matthew P. , Chaux Alcides , Utz Paul J. , Workman Creg J. , Pardoll Drew M. , Korman Alan J. , Drake Charles G. , Vignali Dario A.A.
Published: March 2023

PDF file - 1.1MB
Supplementary Methods from Ectopic ATP Synthase Blockade Suppresses Lung Adenocarcinoma Growth by Activating the Unfolded Protein Response
Authors: Chang Hsin-Yi , Huang Hsuan-Cheng , Huang Tsui-Chin , Yang Pan-Chyr , Wang Yi-Ching , Juan Hsueh-Fen
Published: March 2023

PDF file, 82K, Supplementary materials and methods for cell surface biotinylation, preparation of purified plasma membrane proteins using affinity chromatography, two-dimensional electrophoresis, in-gel digestion, and protein identification.
Supplementary Figure 3 from Transcription Factor NFATc2 Controls the Emergence of Colon Cancer Associated with IL-6–Dependent Colitis
Authors: Gerlach Katharina , Daniel Carolin , Lehr Hans A. , Nikolaev Alexei , Gerlach Thomas , Atreya Raja , Rose-John Stefan , Neurath Markus F. , Weigmann Benno
Published: March 2023

PDF file - 559K, expression of IL-11 and IL-22
Supplementary Figure 6 from Ectopic ATP Synthase Blockade Suppresses Lung Adenocarcinoma Growth by Activating the Unfolded Protein Response
Authors: Chang Hsin-Yi , Huang Hsuan-Cheng , Huang Tsui-Chin , Yang Pan-Chyr , Wang Yi-Ching , Juan Hsueh-Fen
Published: March 2023

PDF file, 234K, Summary of the plausible mechanisms induced by ATP synthase inhibitor citreoviridin.
Supplementary Figure 3 from Ectopic ATP Synthase Blockade Suppresses Lung Adenocarcinoma Growth by Activating the Unfolded Protein Response
Authors: Chang Hsin-Yi , Huang Hsuan-Cheng , Huang Tsui-Chin , Yang Pan-Chyr , Wang Yi-Ching , Juan Hsueh-Fen
Published: March 2023

PDF file, 228K, Protein expression profiles of citreoviridin-treated cells. The protein expression profiles of citreoviridin- (Citreo, lower) treated CL1-0 cells were compared to DMSO- (upper) treated controls on a time-course from 12 to 72 h.
Supplementary Video 3 from Tumor Cell–Derived Angiopoietin-like Protein ANGPTL2 Is a Critical Driver of Metastasis
Authors: Endo Motoyoshi , Nakano Masahiro , Kadomatsu Tsuyoshi , Fukuhara Shigetomo , Kuroda Hiroaki , Mikami Shuji , Hato Tai , Aoi Jun , Horiguchi Haruki , Miyata Keishi , Odagiri Haruki , Masuda Tetsuro , Harada Masahiko , Horio Hirotoshi , Hishima Tsunekazu , Nomori Hiroaki , Ito Takaaki , Yamamoto Yutaka , Minami Takashi , Okada Seiji , Takahashi Takashi , Mochizuki Naoki , Iwase Hirotaka , Oike Yuichi
Published: March 2023

AVI file - 2.3MB
Supplementary Video 1 from Tumor Cell–Derived Angiopoietin-like Protein ANGPTL2 Is a Critical Driver of Metastasis
Authors: Endo Motoyoshi , Nakano Masahiro , Kadomatsu Tsuyoshi , Fukuhara Shigetomo , Kuroda Hiroaki , Mikami Shuji , Hato Tai , Aoi Jun , Horiguchi Haruki , Miyata Keishi , Odagiri Haruki , Masuda Tetsuro , Harada Masahiko , Horio Hirotoshi , Hishima Tsunekazu , Nomori Hiroaki , Ito Takaaki , Yamamoto Yutaka , Minami Takashi , Okada Seiji , Takahashi Takashi , Mochizuki Naoki , Iwase Hirotaka , Oike Yuichi
Published: March 2023

AVI file - 6.8MB
Supplementary Figure Legends 1-8 from Raf Kinase Inhibitor RKIP Inhibits MDA-9/Syntenin-Mediated Metastasis in Melanoma
Authors: Das Swadesh K. , Bhutia Sujit K. , Sokhi Upneet K. , Azab Belal , Su Zhao-zhong , Boukerche Habib , Anwar Talha , Moen Erika L. , Chatterjee Devasis , Pellecchia Maurizio , Sarkar Devanand , Fisher Paul B.
Published: March 2023

PDF file - 80K
Supplementary Figure 1 from Bioactivity and Prognostic Significance of Growth Differentiation Factor GDF15 Secreted by Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma
Authors: Corre Jill , Labat Elodie , Espagnolle Nicolas , Hébraud Benjamin , Avet-Loiseau Hervé , Roussel Murielle , Huynh Anne , Gadelorge Mélanie , Cordelier Pierre , Klein Bernard , Moreau Philippe , Facon Thierry , Fournié Jean-Jacques , Attal Michel , Bourin Philippe
Published: March 2023

PDF file - 67K, Effect of GDF15 on T308 Akt phosphorylation of MOLP-6 stroma-dependent cells in culture condition with 10% fetal calf serum
Supplementary Figure 2 from Raf Kinase Inhibitor RKIP Inhibits MDA-9/Syntenin-Mediated Metastasis in Melanoma
Authors: Das Swadesh K. , Bhutia Sujit K. , Sokhi Upneet K. , Azab Belal , Su Zhao-zhong , Boukerche Habib , Anwar Talha , Moen Erika L. , Chatterjee Devasis , Pellecchia Maurizio , Sarkar Devanand , Fisher Paul B.
Published: March 2023

PDF file - 1.8MB, Expression of MDA-9 and RKIP in clinical samples
Supplementary Figure Legends 1-10 from Metastasis Suppressor NM23-H1 Promotes Repair of UV-Induced DNA Damage and Suppresses UV-Induced Melanomagenesis
Authors: Jarrett Stuart G. , Novak Marian , Dabernat Sandrine , Daniel Jean-Yves , Mellon Isabel , Zhang Qingbei , Harris Nathan , Ciesielski Michael J. , Fenstermaker Robert A. , Kovacic Diane , Slominski Andrzej , Kaetzel David M.
Published: March 2023

PDF file - 111K
Supplementary Figures 1-6, Tables 1-2 from Tumor Suppressive MicroRNAs miR-34a/c Control Cancer Cell Expression of ULBP2, a Stress-Induced Ligand of the Natural Killer Cell Receptor NKG2D
Authors: Heinemann Anja , Zhao Fang , Pechlivanis Sonali , Eberle Jürgen , Steinle Alexander , Diederichs Sven , Schadendorf Dirk , Paschen Annette
Published: March 2023

PDF file - 277K
Supplementary Figure 5 from Metastasis Suppressor NM23-H1 Promotes Repair of UV-Induced DNA Damage and Suppresses UV-Induced Melanomagenesis
Authors: Jarrett Stuart G. , Novak Marian , Dabernat Sandrine , Daniel Jean-Yves , Mellon Isabel , Zhang Qingbei , Harris Nathan , Ciesielski Michael J. , Fenstermaker Robert A. , Kovacic Diane , Slominski Andrzej , Kaetzel David M.
Published: March 2023

PDF file - 114K
Supplementary Table 1 from Critical Function for Nuclear Envelope Protein TMEM209 in Human Pulmonary Carcinogenesis
Authors: Fujitomo Takashi , Daigo Yataro , Matsuda Koichi , Ueda Koji , Nakamura Yusuke
Published: March 2023

PDF file - 16K, Resource and histological type of lung cancer cell lines
Supplementary Figure 3 from Critical Function for Nuclear Envelope Protein TMEM209 in Human Pulmonary Carcinogenesis
Authors: Fujitomo Takashi , Daigo Yataro , Matsuda Koichi , Ueda Koji , Nakamura Yusuke
Published: March 2023

PDF file - 47K, Reduction of STAT3 and p65 proteins after transfection of si-TMEM209 or NUP205 with MG132 treatment
Supplementary Figure 2 from Critical Function for Nuclear Envelope Protein TMEM209 in Human Pulmonary Carcinogenesis
Authors: Fujitomo Takashi , Daigo Yataro , Matsuda Koichi , Ueda Koji , Nakamura Yusuke
Published: March 2023

PDF file - 150K, Reduction of c-Myc protein after transfection of si-TMEM209 or NUP205 without MG132 treatment
Supplementary Methods from AMPKα Modulation in Cancer Progression: Multilayer Integrative Analysis of the Whole Transcriptome in Asian Gastric Cancer
Authors: Kim Yon Hui , Liang Han , Liu Xiuping , Lee Ju-Seog , Cho Jae Yong , Cheong Jae-Ho , Kim Hoguen , Li Min , Downey Thomas J. , Dyer Matthew D. , Sun Yongming , Sun Jingtao , Beasley Ellen M. , Chung Hyun Cheol , Noh Sung Hoon , Weinstein John N. , Liu Chang-Gong , Powis Garth
Published: March 2023

PDF file - 51K
Supplementary Table 2 from IKK-ϵ Coordinates Invasion and Metastasis of Ovarian Cancer
Authors: Hsu Sarah , Kim Marianne , Hernandez Lidia , Grajales Valentina , Noonan Anne , Anver Miriam , Davidson Ben , Annunziata Christina M.
Published: March 2023

PDF file - 23K, IKK isoform IHC scoring
Supplementary Table 1 from IKK-ϵ Coordinates Invasion and Metastasis of Ovarian Cancer
Authors: Hsu Sarah , Kim Marianne , Hernandez Lidia , Grajales Valentina , Noonan Anne , Anver Miriam , Davidson Ben , Annunziata Christina M.
Published: March 2023

PDF file - 155K, Short hairpin RNA sequences
Supplementary Methods, Figure Legends 1-4 from IKK-ϵ Coordinates Invasion and Metastasis of Ovarian Cancer
Authors: Hsu Sarah , Kim Marianne , Hernandez Lidia , Grajales Valentina , Noonan Anne , Anver Miriam , Davidson Ben , Annunziata Christina M.
Published: March 2023

PDF file - 67K
Supplementary Figure Legends 1-7 from Dysfunction of Nucleus Accumbens-1 Activates Cellular Senescence and Inhibits Tumor Cell Proliferation and Oncogenesis
Authors: Zhang Yi , Cheng Yan , Ren Xingcong , Hori Tsukasa , Huber-Keener Kathryn J. , Zhang Li , Yap Kai Lee , Liu David , Shantz Lisa , Qin Zheng-Hong , Zhang Suping , Wang Jianrong , Wang Hong-Gang , Shih Ie-Ming , Yang Jin-Ming
Published: March 2023

PDF file - 120K
Supplementary Table 1 from Receptor Tyrosine Kinase Genes Amplified in Glioblastoma Exhibit a Mutual Exclusivity in Variable Proportions Reflective of Individual Tumor Heterogeneity
Authors: Little Suzanne E. , Popov Sergey , Jury Alexa , Bax Dorine A. , Doey Lawrence , Al-Sarraj Safa , Jurgensmeier Juliane M. , Jones Chris
Published: March 2023

XLS file - 249K
Supplementary Figures 1-11 from Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death
Authors: Cheng Gang , Zielonka Jacek , Dranka Brian P. , McAllister Donna , Mackinnon A. Craig , Joseph Joy , Kalyanaraman Balaraman
Published: March 2023

PDF file - 990K
Supplementary Figure 5 from CD44 Proteolysis Increases CREB Phosphorylation and Sustains Proliferation of Thyroid Cancer Cells
Authors: De Falco Valentina , Tamburrino Anna , Ventre Simona , Castellone Maria Domenica , Malek Mouhannad , Manié Serge N. , Santoro Massimo
Published: March 2023

PDF file - 78K, CD44-ICD expression in human thyroid cancer cell lines
Supplementary Figure 1 from Interleukin-17 Promotes Formation and Growth of Prostate Adenocarcinoma in Mouse Models
Authors: Zhang Qiuyang , Liu Sen , Ge Dongxia , Zhang Qingsong , Xue Yun , Xiong Zhenggang , Abdel-Mageed Asim B. , Myers Leann , Hill Steven M. , Rowan Brian G. , Sartor Oliver , Melamed Jonathan , Chen Zhenbang , You Zongbing
Published: March 2023

PDF file - 3MB, Percentages of PIN and invasive adenocarcinoma in different prostatic lobes.
Supplementary Table 1 from LIGHT Delivery to Tumors by Mesenchymal Stem Cells Mobilizes an Effective Antitumor Immune Response
Authors: Zou Weibin , Zheng Huilin , He Tong-Chuan , Chang Jinjia , Fu Yang-Xin , Fan Weimin
Published: March 2023

PDF file - 64K, MSC-L can exert therapeutic effect to inhibit tumor growth and induce immune
Supplementary Figure 3 from LIGHT Delivery to Tumors by Mesenchymal Stem Cells Mobilizes an Effective Antitumor Immune Response
Authors: Zou Weibin , Zheng Huilin , He Tong-Chuan , Chang Jinjia , Fu Yang-Xin , Fan Weimin
Published: March 2023

PDF file - 1.8MB, Transfection with retroviral vector without LIGHT did not protect the host against tumor
Supplementary Figure 2 from LIGHT Delivery to Tumors by Mesenchymal Stem Cells Mobilizes an Effective Antitumor Immune Response
Authors: Zou Weibin , Zheng Huilin , He Tong-Chuan , Chang Jinjia , Fu Yang-Xin , Fan Weimin
Published: March 2023

PDF file - 2MB, MSC, MSC-mock, and MSC-L have similar infiltration pattern in tumor tissues
Supplementary Figure 5 from Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
Authors: Verbrugge Inge , Hagekyriakou Jim , Sharp Leslie L. , Galli Mara , West Alison , McLaughlin Nicole M. , Duret Hélène , Yagita Hideo , Johnstone Ricky W. , Smyth Mark J. , Haynes Nicole M.
Published: March 2023

PDF file - 282K, Analysis of the combined therapeutic effects of radiotherapy and alpha-CD137/alpha-PD-1 therapy in established 4T1.2 tumors
Supplementary Figure 9 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: March 2023

PDF file - 247K
Supplementary Figure 4 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: March 2023

PDF file - 476K
Supplementary Figure 3 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: March 2023

PDF file - 280K
Supplementary Figure 1 from Systemic Combination Virotherapy for Melanoma with Tumor Antigen-Expressing Vesicular Stomatitis Virus and Adoptive T-cell Transfer
Authors: Rommelfanger Diana M. , Wongthida Phonphimon , Diaz Rosa M. , Kaluza Karen M. , Thompson Jill M. , Kottke Timothy J. , Vile Richard G.
Published: March 2023

PDF file, 44K, Gr1 expression.
Supplementary Figure 2 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: March 2023

PDF file - 309K
Supplementary Figure 1 from Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival
Authors: Robert Francis , Mills John R. , Agenor Aouod , Wang Dantong , DiMarco Sergio , Cencic Regina , Tremblay Michel L. , Gallouzi Imed Eddine , Hekimi Siegfried , Wing Simon S. , Pelletier Jerry
Published: March 2023

PDF file - 517K
Supplementary Figure 2 from Embryonic Protein Nodal Promotes Breast Cancer Vascularization
Authors: Quail Daniela F. , Walsh Logan A. , Zhang Guihua , Findlay Scott D. , Moreno Juan , Fung Laura , Ablack Amber , Lewis John D. , Done Susan J. , Hess David A. , Postovit Lynne-Marie
Published: March 2023

PDF file - 1MB, Nodal co-localizes with CD31 in human breast cancer
Supplementary Methods from Reprogramming Tumor-Associated Dendritic Cells In Vivo Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer
Authors: Cubillos-Ruiz Juan R. , Baird Jason R. , Tesone Amelia J. , Rutkowski Melanie R. , Scarlett Uciane K. , Camposeco-Jacobs Ana L. , Anadon-Arnillas Jorge , Harwood Noah M. , Korc Murray , Fiering Steven N. , Sempere Lorenzo F. , Conejo-Garcia Jose R.
Published: March 2023

PDF file - 107K
Supplementary Figure Legend from Reprogramming Tumor-Associated Dendritic Cells In Vivo Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer
Authors: Cubillos-Ruiz Juan R. , Baird Jason R. , Tesone Amelia J. , Rutkowski Melanie R. , Scarlett Uciane K. , Camposeco-Jacobs Ana L. , Anadon-Arnillas Jorge , Harwood Noah M. , Korc Murray , Fiering Steven N. , Sempere Lorenzo F. , Conejo-Garcia Jose R.
Published: March 2023

PDF file - 76K
Supplementary Figure 2 from TGF-β and αvβ6 Integrin Act in a Common Pathway to Suppress Pancreatic Cancer Progression
Authors: Hezel Aram F. , Deshpande Vikram , Zimmerman Stephanie M. , Contino Gianmarco , Alagesan Brinda , O'Dell Michael R. , Rivera Lee B. , Harper Jay , Lonning Scott , Brekken Rolf A. , Bardeesy Nabeel
Published: March 2023

PDF file - 1.5MB, Tumor histology, grade and subtype were not altered between treatment cohorts
Supplementary Figure 4 from Increased Survival of Glioblastoma Patients Who Respond to Antiangiogenic Therapy with Elevated Blood Perfusion
Authors: Sorensen A. Gregory , Emblem Kyrre E. , Polaskova Pavlina , Jennings Dominique , Kim Heisoog , Ancukiewicz Marek , Wang Meiyun , Wen Patrick Y. , Ivy Percy , Batchelor Tracy T. , Jain Rakesh K.
Published: March 2023

PDF file - 1.3MB, Figure S4: Macrovessel Flow and Response to Treatment. (A) Similar to microvessel flow, analysis of total (macrovessel) flow show three types of response to anti-angiogenic treatment: increase in flow (6 patients), stable flow (13 patients) or decrease in flow (11 patients). (B) Applying the patients groups from microvessel tumor flow analysis on the macrovessel tumor flow data. Figures show log-scaled averaged values (�SEM) and the day -1 values were set as 100% in all lesions. P-values show results of Kruskal-Wallis tests for the difference between the three patient groups at each study day (Holm-Bonferroni corrected).
Supplementary Figure 2 from Cancer Vaccination Drives Nanog-Dependent Evolution of Tumor Cells toward an Immune-Resistant and Stem-like Phenotype
Authors: Noh Kyung Hee , Lee Young-Ho , Jeon Ju-Hong , Kang Tae Heung , Mao Chih-Ping , Wu T.-C. , Kim Tae Woo
Published: March 2023

PDF file - 65K
Supplementary Figure 1 from Cancer Vaccination Drives Nanog-Dependent Evolution of Tumor Cells toward an Immune-Resistant and Stem-like Phenotype
Authors: Noh Kyung Hee , Lee Young-Ho , Jeon Ju-Hong , Kang Tae Heung , Mao Chih-Ping , Wu T.-C. , Kim Tae Woo
Published: March 2023

PDF file - 91K
Supplementary Table 1, Figures 1-8 from Modulation of Microenvironment Acidity Reverses Anergy in Human and Murine Tumor-Infiltrating T Lymphocytes
Authors: Calcinotto Arianna , Filipazzi Paola , Grioni Matteo , Iero Manuela , De Milito Angelo , Ricupito Alessia , Cova Agata , Canese Rossella , Jachetti Elena , Rossetti Monica , Huber Veronica , Parmiani Giorgio , Generoso Luca , Santinami Mario , Borghi Martina , Fais Stefano , Bellone Matteo , Rivoltini Licia
Published: March 2023

PDF file - 136K
Supplementary Figure 2 from Caveolin-1 Increases Aerobic Glycolysis in Colorectal Cancers by Stimulating HMGA1-Mediated GLUT3 Transcription
Authors: Ha Tae-Kyu , Her Nam-Gu , Lee Min-Goo , Ryu Byung-Kyu , Lee Jin-Hee , Han Jikhyon , Jeong Seong-In , Kang Min-Ju , Kim Nam-Hoon , Kim Hyo-Jong , Chi Sung-Gil
Published: March 2023

PDF file- 233K, CAV1 effect on AMPK-p53 signaling
Supplementary Methods from The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation
Authors: Jun Hyun Jung , Johnson Hannah , Bronson Roderick T. , de Feraudy Sebastien , White Forest , Charest Alain
Published: March 2023

PDF file - 91K
Supplementary Table 3 from Inhibitory Roles of Signal Transducer and Activator of Transcription 3 in Antitumor Immunity during Carcinogen-Induced Lung Tumorigenesis
Authors: Ihara Shoichi , Kida Hiroshi , Arase Hisashi , Tripathi Lokesh P. , Chen Yi-An , Kimura Tetsuya , Yoshida Mitsuhiro , Kashiwa Yozo , Hirata Haruhiko , Fukamizu Reiko , Inoue Ruriko , Hasegawa Kana , Goya Sho , Takahashi Ryo , Minami Toshiyuki , Tsujino Kazuyuki , Suzuki Mayumi , Kohmo Satoshi , Inoue Koji , Nagatomo Izumi , Takeda Yoshito , Kijima Takashi , Mizuguchi Kenji , Tachibana Isao , Kumanogoh Atsushi
Published: March 2023

PDF file - 63K, Up-regulated PPI network
Supplementary Figure 6 from Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
Authors: Fokas Emmanouil , Im Jae Hong , Hill Sally , Yameen Sabira , Stratford Michael , Beech John , Hackl Wolfgang , Maira Sauveur-Michel , Bernhard Eric J. , McKenna W. Gillies , Muschel Ruth J.
Published: March 2023

PDf file - 796K
Supplementary Table 1 from Inhibitory Roles of Signal Transducer and Activator of Transcription 3 in Antitumor Immunity during Carcinogen-Induced Lung Tumorigenesis
Authors: Ihara Shoichi , Kida Hiroshi , Arase Hisashi , Tripathi Lokesh P. , Chen Yi-An , Kimura Tetsuya , Yoshida Mitsuhiro , Kashiwa Yozo , Hirata Haruhiko , Fukamizu Reiko , Inoue Ruriko , Hasegawa Kana , Goya Sho , Takahashi Ryo , Minami Toshiyuki , Tsujino Kazuyuki , Suzuki Mayumi , Kohmo Satoshi , Inoue Koji , Nagatomo Izumi , Takeda Yoshito , Kijima Takashi , Mizuguchi Kenji , Tachibana Isao , Kumanogoh Atsushi
Published: March 2023

PDF file - 117K, Genes up-regulated (>2.0) in Stat3delta/delta compared with Stat3flox/flox
Supplementary Figure 3 from Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
Authors: Fokas Emmanouil , Im Jae Hong , Hill Sally , Yameen Sabira , Stratford Michael , Beech John , Hackl Wolfgang , Maira Sauveur-Michel , Bernhard Eric J. , McKenna W. Gillies , Muschel Ruth J.
Published: March 2023

PDf file - 739K
Supplementary Figure 1 from Inhibitory Roles of Signal Transducer and Activator of Transcription 3 in Antitumor Immunity during Carcinogen-Induced Lung Tumorigenesis
Authors: Ihara Shoichi , Kida Hiroshi , Arase Hisashi , Tripathi Lokesh P. , Chen Yi-An , Kimura Tetsuya , Yoshida Mitsuhiro , Kashiwa Yozo , Hirata Haruhiko , Fukamizu Reiko , Inoue Ruriko , Hasegawa Kana , Goya Sho , Takahashi Ryo , Minami Toshiyuki , Tsujino Kazuyuki , Suzuki Mayumi , Kohmo Satoshi , Inoue Koji , Nagatomo Izumi , Takeda Yoshito , Kijima Takashi , Mizuguchi Kenji , Tachibana Isao , Kumanogoh Atsushi
Published: March 2023

PDF file - 41K, Stat3delta/delta did not acquire large tumors compared to Stat3flox/flox mice
Supplementary Methods, Table 1, Figures 1-7 from Manganese Superoxide Dismutase Regulates a Metabolic Switch during the Mammalian Cell Cycle
Authors: Sarsour Ehab H. , Kalen Amanda L. , Xiao Zhen , Veenstra Timothy D. , Chaudhuri Leena , Venkataraman Sujatha , Reigan Philip , Buettner Garry R. , Goswami Prabhat C.
Published: March 2023

PDF file - 964K, Results presented in this section show: (1) A minimal difference in cell cycle phase distributions in MnSOD (+/+), and (-/-) MEFs following re-entry into the proliferative cycle (Table I) (2) An increase in MnSOD protein levels and activity in MnSOD overexpressing MB231 human mammary epithelial cancer cells (Figure 1) (3) An inhibition of MnSOD activity in quiescent normal human fibroblasts was associated with an increase in glucose consumption and percent S-phase (Figure 2) (4) Cell cycle phase-associated increase in cellular ROS levels was absent in MnSOD (-/-) MEFs (Figure 3) (5) Cell cycle phase specific increase in DHE-fluorescence is primarily due to an increase in cellular steady-state levels of superoxide (Figure 4) (6) Mass spectrometry results identifying lysine and arginine methylation pattern of MnSOD during quiescence and proliferation; species conservation of lysine and arginine methylation sites in MnSOD (Figure 5) (7) Site directed mutagenesis approach to mutate lysine 89 and 202 of MnSOD, and engineer expression vectors of wild-type and K-to-A mutant carrying human MnSOD cDNAs (Figure 6). (8) Computer modeling of MnSOD-methylation pattern (Figure 7)
Supplementary Figure 1 from Proline Oxidase Promotes Tumor Cell Survival in Hypoxic Tumor Microenvironments
Authors: Liu Wei , Glunde Kristine , Bhujwalla Zaver M. , Raman Venu , Sharma Anit , Phang James M.
Published: March 2023

PDF file - 191K, Hypoxia upregulates POX expression in TK10 and Hs-578-T cell lines through AMPK activation
Supplementary Table 1 from HSP DNAJB8 Controls Tumor-Initiating Ability in Renal Cancer Stem–like Cells
Authors: Nishizawa Satoshi , Hirohashi Yoshihiko , Torigoe Toshihiko , Takahashi Akari , Tamura Yasuaki , Mori Takashi , Kanaseki Takayuki , Kamiguchi Kenjiro , Asanuma Hiroko , Morita Rena , Sokolovskaya Alice , Matsuzaki Junichi , Yamada Ren , Fujii Reona , Kampinga Harm H. , Kondo Toru , Hasegawa Tadashi , Hara Isao , Sato Noriyuki
Published: March 2023

PDF file - 23K, List of Primers
Supplementary Figure 2 from Sorafenib Has Potent Antitumor Activity against Multiple Myeloma In Vitro, Ex Vivo, and In Vivo in the 5T33MM Mouse Model
Authors: Kharaziha Pedram , De Raeve Hendrik , Fristedt Charlotte , Li Qiao , Gruber Astrid , Johnsson Per , Kokaraki Georgia , Panzar Maria , Laane Edward , Österborg Anders , Zhivotovsky Boris , Jernberg-Wiklund Helena , Grandér Dan , Celsing Fredrik , Björkholm Magnus , Vanderkerken Karin , Panaretakis Theocharis
Published: March 2023

PDF file - 106K, Immunoblot analysis of the indicated proteins in U-266 and LP-1 pre-treated with 10 muM CQ, 10 muM zVAD.fmk or 4 muM MG132 (for 4h) followed by 10 mu M Sor for 24h
Supplementary Figure 1 from HSP DNAJB8 Controls Tumor-Initiating Ability in Renal Cancer Stem–like Cells
Authors: Nishizawa Satoshi , Hirohashi Yoshihiko , Torigoe Toshihiko , Takahashi Akari , Tamura Yasuaki , Mori Takashi , Kanaseki Takayuki , Kamiguchi Kenjiro , Asanuma Hiroko , Morita Rena , Sokolovskaya Alice , Matsuzaki Junichi , Yamada Ren , Fujii Reona , Kampinga Harm H. , Kondo Toru , Hasegawa Tadashi , Hara Isao , Sato Noriyuki
Published: March 2023

PDF file - 68K, Isolation of CSCs/CICs from human RCC cells
Supplementary Figure 7 from NLRP3 Suppresses NK Cell–Mediated Responses to Carcinogen-Induced Tumors and Metastases
Authors: Chow Melvyn T. , Sceneay Jaclyn , Paget Christophe , Wong Christina S.F. , Duret Helene , Tschopp Jürg , Möller Andreas , Smyth Mark J.
Published: March 2023

PDF file 2632K, CD11b+ Gr-1int cells express NLRP3.
Supplementary Figure 6 from NLRP3 Suppresses NK Cell–Mediated Responses to Carcinogen-Induced Tumors and Metastases
Authors: Chow Melvyn T. , Sceneay Jaclyn , Paget Christophe , Wong Christina S.F. , Duret Helene , Tschopp Jürg , Möller Andreas , Smyth Mark J.
Published: March 2023

PDF file 3180K, Normal NK cell homeostasis in NLRP3-/- mice.
Supplementary Figure 5 from NLRP3 Suppresses NK Cell–Mediated Responses to Carcinogen-Induced Tumors and Metastases
Authors: Chow Melvyn T. , Sceneay Jaclyn , Paget Christophe , Wong Christina S.F. , Duret Helene , Tschopp Jürg , Möller Andreas , Smyth Mark J.
Published: March 2023

PDF file 1235K, Caspase-1 and IL-1 do not affect the development of lung metastasis.
Supplementary Figure 3 from NLRP3 Suppresses NK Cell–Mediated Responses to Carcinogen-Induced Tumors and Metastases
Authors: Chow Melvyn T. , Sceneay Jaclyn , Paget Christophe , Wong Christina S.F. , Duret Helene , Tschopp Jürg , Möller Andreas , Smyth Mark J.
Published: March 2023

PDF file 1188K, Caspase-1 inflammasome promotes MCA-induced carcinogenesis.
Supplementary Figure 2 from NLRP3 Suppresses NK Cell–Mediated Responses to Carcinogen-Induced Tumors and Metastases
Authors: Chow Melvyn T. , Sceneay Jaclyn , Paget Christophe , Wong Christina S.F. , Duret Helene , Tschopp Jürg , Möller Andreas , Smyth Mark J.
Published: March 2023

PDF file 921K, The growth rate of MCA-induced fibrosarcomas.
Supplementary Figure Legends 1-10 from Metastatic Cells Can Escape the Proapoptotic Effects of TNF-α through Increased Autocrine IL-6/STAT3 Signaling
Authors: Li Shun , Wang Ni , Brodt Pnina
Published: March 2023

PDF file - 77K
Supplementary Table 4 from Monoallelic Expression Determines Oncogenic Progression and Outcome in Benign and Malignant Brain Tumors
Authors: Walker Erin J. , Zhang Cindy , Castelo-Branco Pedro , Hawkins Cynthia , Wilson Wes , Zhukova Nataliya , Alon Noa , Novokmet Ana , Baskin Berivan , Ray Peter , Knobbe Christiane , Dirks Peter , Taylor Michael D. , Croul Sidney , Malkin David , Tabori Uri
Published: March 2023

PDF file - 39K
Supplementary Video 1 from Nanobody-Based Targeting of the Macrophage Mannose Receptor for Effective In Vivo Imaging of Tumor-Associated Macrophages
Authors: Movahedi Kiavash , Schoonooghe Steve , Laoui Damya , Houbracken Isabelle , Waelput Wim , Breckpot Karine , Bouwens Luc , Lahoutte Tony , De Baetselier Patrick , Raes Geert , Devoogdt Nick , Van Ginderachter Jo A.
Published: March 2023

AVI file - 102K, Full 3D reconstruction of whole body SPECT/CT images visualizing MMR+ cells specifically in a subcutaneous TS/A tumor
Supplementary Figure Legends 1-8 from CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
Authors: Velasco-Velázquez Marco , Jiao Xuanmao , De La Fuente Marisol , Pestell Timothy G. , Ertel Adam , Lisanti Michael P. , Pestell Richard G.
Published: March 2023

PDF file - 110K
Supplementary Figure 5 from Numb Regulates Stability and Localization of the Mitotic Kinase PLK1 and Is Required for Transit through Mitosis
Authors: Schmit Travis L. , Nihal Minakshi , Ndiaye Mary , Setaluri Vijayasaradhi , Spiegelman Vladimir S. , Ahmad Nihal
Published: March 2023

PDF file - 5.5MB, To determine if the localization of Plk1 is regulated by Numb (as seen in A375 cells; Figure 4B) in other cell types, we repeated immunofluorescent analysis for Plk1 and gamma-tubulin in the diploid fibroblast cells, TiG. Plk1 (red) and gamma-tubulin (green). Scale bar = 10 mu m
Supplementary Figure 6 from CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
Authors: Velasco-Velázquez Marco , Jiao Xuanmao , De La Fuente Marisol , Pestell Timothy G. , Ertel Adam , Lisanti Michael P. , Pestell Richard G.
Published: March 2023

PDF file - 78K, Pulmonary tumors are enriched in CCR5+4 cells
Supplementary Figure 3 from Numb Regulates Stability and Localization of the Mitotic Kinase PLK1 and Is Required for Transit through Mitosis
Authors: Schmit Travis L. , Nihal Minakshi , Ndiaye Mary , Setaluri Vijayasaradhi , Spiegelman Vladimir S. , Ahmad Nihal
Published: March 2023

PDF file - 371K, To determine if the changes in protein half-life of Plk1 after Numb inhibition is a cell line specific phenomena or is conserved we repeated the half-life experiment (as shown in Figure 3B for A375 cells) in the melanoma cell line, HS294T
Supplementary Figure 2 from Numb Regulates Stability and Localization of the Mitotic Kinase PLK1 and Is Required for Transit through Mitosis
Authors: Schmit Travis L. , Nihal Minakshi , Ndiaye Mary , Setaluri Vijayasaradhi , Spiegelman Vladimir S. , Ahmad Nihal
Published: March 2023

PDF file - 859K, Numb is a mitotically cycling protein. To determine if the mitotically cycling Numb seen in A375 (Figure 2) is conserved in other cells, we reproduced the double thymidine arrest and release protocol in the melanoma cell line, HS294T, and the normal human fibroblast cell line, TiG. The data represent three independent experiments where average G2/M percentage at each time point is shown
Supplementary Figure 5 from CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
Authors: Velasco-Velázquez Marco , Jiao Xuanmao , De La Fuente Marisol , Pestell Timothy G. , Ertel Adam , Lisanti Michael P. , Pestell Richard G.
Published: March 2023

PDF file - 69K, The CCR5 antagonist Maraviroc inhibits lung metastasis in vivo
Supplementary Figure 1 from Numb Regulates Stability and Localization of the Mitotic Kinase PLK1 and Is Required for Transit through Mitosis
Authors: Schmit Travis L. , Nihal Minakshi , Ndiaye Mary , Setaluri Vijayasaradhi , Spiegelman Vladimir S. , Ahmad Nihal
Published: March 2023

PDF file - 1.3MB, Numb knockdown results in a reduction in cell growth. A375 cells were treated with shNS or shNumb targeting virus for 72 hours. 2,000, 200, or 20 viable cells of each treatment were then replated and monitored for two weeks at which point the cells were stained for crystal violet and colonies counted. Data represents mean � standard deviation of three separate experiments with similar results (*p<0.01)
Supplementary Figure 4 from CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
Authors: Velasco-Velázquez Marco , Jiao Xuanmao , De La Fuente Marisol , Pestell Timothy G. , Ertel Adam , Lisanti Michael P. , Pestell Richard G.
Published: March 2023

PDF file - 143K, Expression of CCR5 enhances CCL5-dependent calcium activation
Supplementary Figure 3 from CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
Authors: Velasco-Velázquez Marco , Jiao Xuanmao , De La Fuente Marisol , Pestell Timothy G. , Ertel Adam , Lisanti Michael P. , Pestell Richard G.
Published: March 2023

PDF file - 129K, Human breast cancer cell lines expressing CCR5 respond to CCL5
Supplementary Figure 2 from CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
Authors: Velasco-Velázquez Marco , Jiao Xuanmao , De La Fuente Marisol , Pestell Timothy G. , Ertel Adam , Lisanti Michael P. , Pestell Richard G.
Published: March 2023

PDF file - 104K, Heat map of CCL5 expression and is receptors CCR5, CCR1 and CCR3
Supplementary Table 1 from Smurf2 Regulates the Senescence Response and Suppresses Tumorigenesis in Mice
Authors: Ramkumar Charusheila , Kong Yahui , Cui Hang , Hao Suyang , Jones Stephen N. , Gerstein Rachel M. , Zhang Hong
Published: March 2023

PDF file - 89K, Mouse Smurf2 locus Exons are highlighted in blue, primers used in genomic PCR are highlighted in green and integration site is highlighted in red
Supplementary Figure 5 from Smurf2 Regulates the Senescence Response and Suppresses Tumorigenesis in Mice
Authors: Ramkumar Charusheila , Kong Yahui , Cui Hang , Hao Suyang , Jones Stephen N. , Gerstein Rachel M. , Zhang Hong
Published: March 2023

PDF file - 131K, Hematoxylin & Eosin staining of paraffin-embedded sections of kidney and liver with lymphomas in Smurf2T/T (T/T) and Smurf2+/T (+/T) mice. Scale bar: 100 mu
Supplementary Figure 3 from Fra-1 Promotes Breast Cancer Chemosensitivity by Driving Cancer Stem Cells from Dormancy
Authors: Lu Dan , Chen Si , Tan Xiaoyue , Li Na , Liu Chenghu , Li Zongjin , Liu Ze , Stupack Dwayne G. , Reisfeld Ralph A. , Xiang Rong
Published: March 2023

PDF file - 159K, Cell proliferation was evaluated by cell cycle analysis. Cell cycle profiles of 4TO7 cells with Fra-1 extinction (A) and ectopic expression (B) were confirmed by FACS. Cells were fixed by 70% ethanol, incubated in PBS buffer with RNase A and then stained with propidium iodide (PI) overnight. Data were collected on the following day
Supplementary Figure 1 from Smurf2 Regulates the Senescence Response and Suppresses Tumorigenesis in Mice
Authors: Ramkumar Charusheila , Kong Yahui , Cui Hang , Hao Suyang , Jones Stephen N. , Gerstein Rachel M. , Zhang Hong
Published: March 2023

PDF file - 73K, Characterization of a Smurf2-deficient mouse model
Supplementary Table 1 from Identification of Molecular Vulnerabilities in Human Multiple Myeloma Cells by RNA Interference Lethality Screening of the Druggable Genome
Authors: Tiedemann Rodger E. , Zhu Yuan Xao , Schmidt Jessica , Shi Chang Xin , Sereduk Chris , Yin Hongwei , Mousses Spyro , Stewart A. Keith
Published: March 2023

PDF file - 1.3MB, Druggable Genome v2 siRNA primary screen results
Supplementary Table 3 from Common Structural and Epigenetic Changes in the Genome of Castration-Resistant Prostate Cancer
Authors: Friedlander Terence W. , Roy Ritu , Tomlins Scott A. , Ngo Vy T. , Kobayashi Yasuko , Azameera Aruna , Rubin Mark A. , Pienta Kenneth J. , Chinnaiyan Arul , Ittmann Michael M. , Ryan Charles J. , Paris Pamela L.
Published: March 2023

XLS file - 49K, CpG sites methylated in 100% of CRPC.
Supplementary Table 2 from Common Structural and Epigenetic Changes in the Genome of Castration-Resistant Prostate Cancer
Authors: Friedlander Terence W. , Roy Ritu , Tomlins Scott A. , Ngo Vy T. , Kobayashi Yasuko , Azameera Aruna , Rubin Mark A. , Pienta Kenneth J. , Chinnaiyan Arul , Ittmann Michael M. , Ryan Charles J. , Paris Pamela L.
Published: March 2023

XLS file - 15K, Genes with copy number aberrations in _>66% of samples (N=15).
Supplementary Methods from Control of Breast Cancer Growth and Initiation by the Stem Cell–Associated Transcription Factor TCF3
Authors: Slyper Michal , Shahar Amit , Bar-Ziv Anat , Granit Roy Z. , Hamburger Tamar , Maly Bella , Peretz Tamar , Ben-Porath Ittai
Published: March 2023

PDF file - 168K
Supplementary Table 5 from Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors
Authors: Bai Yun , Li Jiannong , Fang Bin , Edwards Arthur , Zhang Guolin , Bui Marilyn , Eschrich Steven , Altiok Soner , Koomen John , Haura Eric B.
Published: March 2023

XLS file - 78K, Proteins with tyrosine phosphorylation sites identified by phosphoproteomics in xenograft human sarcoma tissues
Supplementary Figures 1-4 from Antigen-Specific CD4+ T Cells Regulate Function of Myeloid-Derived Suppressor Cells in Cancer via Retrograde MHC Class II Signaling
Authors: Nagaraj Srinivas , Nelson Allison , Youn Je-in , Cheng Pingyan , Quiceno David , Gabrilovich Dmitry I.
Published: March 2023

PDF file - 405K