bluuebunny/crossref_metadata_2025 huggingface dataset:
Farmland Hydrology Cycle and Agronomic Measures in Agroforestry for the Efficient Utilization of Water Resources under Karst Desertification Environments
Authors: Wu Qinglin , Xiong Kangning , Li Rui , Xiao Jie
Published: February 2023

Severe soil-water loss and unfertile soil frequently occur under karst desertification environments. The surface-underground dual structure in these areas allows the surface water to leak into the subsurface through cracks and sinkholes, as well as other conduits, causing a special “karst drought”. Hence, water-resource shortage has become a challenge for local agricultural development. To realize efficient utilization of water resources, an urgent need is to clearly understand and study the law of farmland hydrological cycles under agroforestry practices, which is still understudied. Here, we focused on the hydrological cycle at the farmland scale and water-saving measures under agroforestry in three study areas representing different degrees of karst desertification. First, a significant positive correlation was found between total and available precipitations as well as land evapotranspiration (LET). Second, under agronomic measures, the soil water content in the three areas was all higher than that of the control group while soil evaporation was all lower. This indicates that agronomic measures can contribute to the efficient use of water resources by halting soil evaporation and increasing soil water content. Third, dwarf dense planting and pruning technologies were helpful in inhibiting crop transpiration and reducing vegetation interception. Fourth, in the farmland hydrological cycle of agroforestry, 77.45% of precipitation transformed into soil water storage, 24.81% into soil evaporation, 20.73% into plant transpiration, 17.40% into groundwater, and 5.18% into vegetation interception. However, their sum was greater than 100%, suggesting that the farmland-scale water cycle is an open system. The implication is that different agronomic practices under agroforestry bring certain water-saving benefits by constraining the conversion of ineffective water and promoting the storage of effective water, thus opening up promising opportunities for efficiently utilizing water resources in karst desertification areas. The finding is also significant to the control of karst desertification, soil and water conservation, and karst drought alleviation.
Mapping the Forest Height by Fusion of ICESat-2 and Multi-Source Remote Sensing Imagery and Topographic Information: A Case Study in Jiangxi Province, China
Authors: Luo Yichen , Qi Shuhua , Liao Kaitao , Zhang Shaoyu , Hu Bisong , Tian Ye
Published: February 2023

Forest canopy height is defined as the distance between the highest point of the tree canopy and the ground, which is considered to be a key factor in calculating above-ground biomass, leaf area index, and carbon stock. Large-scale forest canopy height monitoring can provide scientific information on deforestation and forest degradation to policymakers. The Ice, Cloud, and Land Elevation Satellite-2 (ICESat-2) was launched in 2018, with the Advanced Topographic Laser Altimeter System (ATLAS) instrument taking on the task of mapping and transmitting data as a photon-counting LiDAR, which offers an opportunity to obtain global forest canopy height. To generate a high-resolution forest canopy height map of Jiangxi Province, we integrated ICESat-2 and multi-source remote sensing imagery, including Sentinel-1, Sentinel-2, the Shuttle Radar Topography Mission, and forest age data of Jiangxi Province. Meanwhile, we develop four canopy height extrapolation models by random forest (RF), Support Vector Machine (SVM), K-nearest neighbor (KNN), Gradient Boosting Decision Tree (GBDT) to link canopy height in ICESat-2, and spatial feature information in multi-source remote sensing imagery. The results show that: (1) Forest canopy height is moderately correlated with forest age, making it a potential predictor for forest canopy height mapping. (2) Compared with GBDT, SVM, and KNN, RF showed the best predictive performance with a coefficient of determination (R2) of 0.61 and a root mean square error (RMSE) of 5.29 m. (3) Elevation, slope, and the red-edge band (band 5) derived from Sentinel-2 were significantly dependent variables in the canopy height extrapolation model. Apart from that, Forest age was one of the variables that the RF moderately relied on. In contrast, backscatter coefficients and texture features derived from Sentinel-1 were not sensitive to canopy height. (4) There is a significant correlation between forest canopy height predicted by RF and forest canopy height measured by field measurements (R2 = 0.69, RMSE = 4.02 m). In a nutshell, the results indicate that the method utilized in this work can reliably map the spatial distribution of forest canopy height at high resolution.
Correction: Wang et al. Effectiveness in Mitigating Forest Fire Ignition Sources: A Statistical Study Based on Fire Occurrence Data in China. Fire 2022, 5, 215
Authors: Wang Haihui , Jin Bangxin , Zhang Kaixuan , Aktar Shamima , Song Zhilong
Published: February 2023

In the original publication [...]
Ultrasonic Treatment Enhances the Antioxidant and Immune-Stimulatory Properties of the Polysaccharide from Sinopodophyllum hexandrum Fruit
Authors: Liu Ziwei , Li Hangyu , Liu Qianqian , Feng Yangyang , Wu Daiyan , Zhang Xinnan , Zhang Linzi , Li Sheng , Tang Feng , Liu Qun , Yang Xiaonong , Feng Haibo
Published: February 2023

We aimed to assess the potential of ultrasonic treatment on the processing of polysaccharides as functional foods or food additives. The polysaccharide from Sinopodophyllum hexandrum fruit (SHP, 52.46 kDa, 1.91 nm) was isolated and purified. SHP was treated with various levels of ultrasound (250 W and 500 W), resulting in the formation of two polysaccharides, SHP1 (29.37 kD, 1.40 nm) and SHP2 (36.91 kDa, 0.987 nm). Ultrasonic treatment was found to reduce the surface roughness and molecular weight of the polysaccharides, leading to thinning and fracturing. The effect of ultrasonic treatment on polysaccharide activity was evaluated in vitro and in vivo. In vivo experiments showed that ultrasonic treatment improved the organ index. Simultaneously, it enhanced the activity of superoxide dismutase, total antioxidant capacity, and decreased the content of malondialdehyde in the liver. In vitro experiments demonstrated that ultrasonic treatment also promoted proliferation, nitric oxide secretion, phagocytic efficiency, costimulatory factors (CD80+, CD86+) expression, and cytokine(IL-6, IL-1β) production of RAW264.7 macrophages.
The Development of Dyslipidemia in Chronic Kidney Disease and Associated Cardiovascular Damage, and the Protective Effects of Curcuminoids
Authors: Ceja-Galicia Zeltzin Alejandra , Aranda-Rivera Ana Karina , Amador-Martínez Isabel , Aparicio-Trejo Omar Emiliano , Tapia Edilia , Trujillo Joyce , Ramírez Victoria , Pedraza-Chaverri José
Published: February 2023

Chronic kidney disease (CKD) is a health problem that is constantly growing. This disease presents a diverse symptomatology that implies complex therapeutic management. One of its characteristic symptoms is dyslipidemia, which becomes a risk factor for developing cardiovascular diseases and increases the mortality of CKD patients. Various drugs, particularly those used for dyslipidemia, consumed in the course of CKD lead to side effects that delay the patient’s recovery. Therefore, it is necessary to implement new therapies with natural compounds, such as curcuminoids (derived from the Curcuma longa plant), which can cushion the damage caused by the excessive use of medications. This manuscript aims to review the current evidence on the use of curcuminoids on dyslipidemia in CKD and CKD-induced cardiovascular disease (CVD). We first described oxidative stress, inflammation, fibrosis, and metabolic reprogramming as factors that induce dyslipidemia in CKD and their association with CVD development. We proposed the potential use of curcuminoids in CKD and their utilization in clinics to treat CKD-dyslipidemia.
Longissimus dorsi Muscle’s Chemical Composition, Fatty Acid Pattern, and Oxidative Stability in Korean Hanwoo Finishing Cattle Following Slaughtering and Stunning with or without Brain Disruption and State of Consciousness
Authors: Bostami A. B. M. Rubayet , Mun Hong-Seok , Yang Chul-Ju
Published: February 2023

Handling during pre- and post-slaughter conditions can affect the quality and safety of meat. An experiment was conducted to compare slaughtering with or without a state of consciousness on Longissimus dorsi muscle’s proximate composition, cholesterol content, fatty acid profile, and storage quality (pH, microbiology, and thiobarbituric acid reactive substances (TBARS) value) in Korean Hanwoo finishing cattle (KHFC). Twenty-four KHFC (three replications of four animals per replicate) were slaughtered following two methods: (1) SSUC: slaughtering by applying captive bolt stunning, brain disruption, and neck cutting with the animal in an unconscious state; and (2) SSCS: slaughtering by applying captive bolt stunning, without brain disruption, and neck cutting with the animal in a conscious state. General carcass traits, proximate composition (exempting higher ash content), and cholesterol content of the Longissimus dorsi muscle did not differ between slaughter treatments (SSCS vs. SSUS) (p > 0.05). The total SFA, UFA, PUFA, and MUFA values did not change for those subjected to different slaughtering types; however, some particular SFA values, namely lauric, myristic, and myristoleic acid, were diminished for the SSCS method as compared with the SSUC method (p < 0.05). The Longissimus dorsi muscle’s pH value was elevated (p < 0.05), the microbial population tended to be diminished (p < 0.10), and the TBARS value was suppressed for the SSCS method relative to that of the SSUC method during 2 weeks of storage (p < 0.05). Thus, compared with the SSUC method, the SSCS method ensured splendid storage quality with some positive influence on the proximate composition (total ash content) and fatty acid profile (some specific saturated fatty acids) of the Longissimus dorsi muscle of KHFC.
Instantaneous and Non-Instantaneous Impulsive Boundary Value Problem Involving the Generalized ψ-Caputo Fractional Derivative
Authors: Li Dongping , Li Yankai , Chen Fangqi , Feng Xiaozhou
Published: February 2023

This paper studies a new class of instantaneous and non-instantaneous impulsive boundary value problem involving the generalized ψ-Caputo fractional derivative with a weight. Depending on critical point theorems and some properties of ψ-Caputo-type fractional integration and differentiation, the variational construction and multiplicity result of solutions are established.
Infinitely Many Small Energy Solutions to Schrödinger-Kirchhoff Type Problems Involving the Fractional r(·)-Laplacian in RN
Authors: Kim Yun-Ho
Published: February 2023

This paper is concerned with the existence result of a sequence of infinitely many small energy solutions to the fractional r(·)-Laplacian equations of Kirchhoff–Schrödinger type with concave–convex nonlinearities when the convex term does not require the Ambrosetti–Rabinowitz condition. The aim of the present paper, under suitable assumptions on a nonlinear term, is to discuss the multiplicity result of non-trivial solutions by using the dual fountain theorem as the main tool.
Identification of Aggregate Urban Mobility Patterns of Nonregular Travellers from Mobile Phone Data
Authors: Seppecher Manon , Leclercq Ludovic , Furno Angelo , Vieira da Rocha Thamara , André Jean-Marc , Boutang Jérôme
Published: February 2023

Over the last two decades, mobile phone data have appeared to be a promising data source for mobility analysis. The structure, abundance, and accessibility of call detail records (CDRs) make them particularly suitable for such use. However, their exploitation is often limited to estimating origin–destination matrices of a restricted part of the population: regular travellers. Although these studies provide valuable information for policymakers, their scope remains limited to this subpopulation analysis. In the present work, we develop a collective mobility reconstruction method adapted to nonregular travellers. The method relies on the notion of the detour ratio, which makes it robust to the lack of mobile phone data as well as its application to large instances (large and dense telecommunication networks). It is used to conduct a longitudinal analysis of the macroscopic mobility patterns in Santiago de Cali, Colombia, thanks to call detail data shared by communication provider CLARO as part of a research project conducted by Citepa, Paris, the Green City Big Data Project.
Polymeric Networks Containing Amine Derivatives as Organocatalysts for Knoevenagel Reaction within Continuously Driven Microfluidic Reactors
Authors: Killi Naresh , Bartenbach Julian , Kuckling Dirk
Published: February 2023

The Knoevenagel reaction is a classic reaction in organic chemistry for the formation of C-C bonds. In this study, various catalytic monomers for Knoevenagel reactions were synthesized and polymerized via photolithography to form polymeric gel dots with a composition of 90% catalyst, 9% gelling agent and 1% crosslinker. Furthermore, these gel dots were inserted into a microfluidic reactor (MFR) and the conversion of the reaction using gel dots as catalysts in the MFR for 8 h at room temperature was studied. The gel dots containing primary amines showed a better conversion of about 83–90% with aliphatic aldehyde and 86–100% with aromatic aldehyde, compared to the tertiary amines (52–59% with aliphatic aldehyde and 77–93% with aromatic aldehydes) which resembles the reactivity of the amines. Moreover, the addition of polar solvent (water) in the reaction mixture and the swelling properties of the gel dots by altering the polymer backbone showed a significant enhancement in the conversion of the reaction, due to the increased accessibility of the catalytic sites in the polymeric network. These results suggested the primary-amine-based catalysts facilitate better conversion compared to tertiary amines and the reaction solvent had a significant influence on organocatalysis to improve the efficiency of MFR.
Identity Development and Its Relationship to Family History Knowledge among Late Adolescents
Authors: Haydon Clive G. , Hill Brian J. , Ward Peter J. , Eggett Dennis L.
Published: February 2023

Identity development among late adolescent university students and its relationship to family history knowledge was examined in this study. Identity development was examined using Marcia’s individual developmental framework (1988) of exploration and commitment and Stutman and Lich’s family systems framework (1984) of autonomy and relatedness. It was proposed that late adolescents’ personal exploration of and commitment to roles and values may be influenced by knowledge of parent and grandparent histories. It was also proposed that late adolescents’ achievement of personal autonomy and positive family relatedness may be influenced by knowledge of parent and grandparent histories. The sample consisted of 239 university students. The Parental Relationship Inventory (PRI) and the Ego Identity Process Questionnaire (EIPQ) were used to measure identity development. The Do You Know? (DYK) scale measured family history knowledge. Multiple regression analyses indicated a significant positive relationship between commitment and family history knowledge and relatedness and family history knowledge, a negative relationship between autonomy and family history knowledge, and a weak correlation between exploration and family history knowledge. Findings indicated that family history knowledge may influence components of identity development. This has implications for those working to enhance adolescent development.
Genomic Insights into the Origin of a Thermotolerant Tomato Line and Identification of Candidate Genes for Heat Stress
Authors: Graci Salvatore , Ruggieri Valentino , Francesca Silvana , Rigano Maria Manuela , Barone Amalia
Published: February 2023

Climate change represents the main problem for agricultural crops, and the constitution of heat-tolerant genotypes is an important breeder’s strategy to reduce yield losses. The aim of the present study was to investigate the whole genome of a heat-tolerant tomato genotype (E42), in order to identify candidate genes involved in its response to high temperature. E42 presented a high variability for chromosomes 1, 4, 7 and 12, and phylogenetic analysis highlighted its relationship with the wild S. pimpinellifolium species. Variants with high (18) and moderate (139) impact on protein function were retrieved from two lists of genes related to heat tolerance and reproduction. This analysis permitted us to prioritize a subset of 35 candidate gene mapping in polymorphic regions, some colocalizing in QTLs controlling flowering in tomato. Among these genes, we identified 23 HSPs, one HSF, six involved in flowering and five in pollen activity. Interestingly, one gene coded for a flowering locus T1 and mapping on chromosome 11 resides in a QTL region controlling flowering and also showed 100% identity with an S. pimpinellifolium allele. This study provides useful information on both the E42 genetic background and heat stress response, and further studies will be conducted to validate these genes.
Association of the STAT4 Gene rs7574865 Polymorphism with IFN-γ Levels in Patients with Systemic Lupus Erythematosus
Authors: Esparza Guerrero Yussef , Vazquez Villegas Maria Luisa , Nava Valdivia Cesar Arturo , Ponce Guarneros Juan Manuel , Perez Guerrero Edsaul Emilio , Gomez Ramirez Eli Efrain , Ramirez Villafaña Melissa , Contreras Haro Betsabe , Martinez Hernandez Alejandra , Cardona Muñoz Ernesto German , Nuño Arana Ismael , Gallardo Moya Sergio Gabriel , Celis Alfredo , Gonzalez Lopez Laura , Gamez Nava Jorge Ivan , Saldaña Cruz Ana Miriam
Published: February 2023

STAT4 plays an important role in disease activity in SLE patients. STAT4 particles have the capacity to activate the transcription of genes associated with the production of TH1 and Th17 lymphocytes, with a greater predominance on the production of IFN-γ and IL-17A. The presence of variants in STAT4 genes has a major impact on the generation of autoimmunity. However, there are few studies evaluating the impact of these variants on the production of proinflammatory cytokines such as IFN-γ and IL-17A. Methods—A case–control study was carried out with 206 Mexican mestizo patients residing in Western Mexico with a diagnosis of SLE and a group of 80 patients without autoimmune diseases was captured to determine the cut-off point for high IFN-γ levels. In this study, SLE patients with high IFN-γ levels were considered as cases (cut-off > 15.6 pg/mL), and SLE patients with normal IFN-γ levels were considered as controls (cut-off ≤ 15.6 pg/mL). Disease activity was identified from the systemic lupus erythematosus disease activity index (SLEDAI). For the determination of levels of cytokines IFN-γ, IL-12, and IL17A, commercial ELISA kits were used. Genotyping of STAT4 rs7574865 (G > T) was performed by quantitative polymerase chain reaction (qPCR) using TaqMan probes. Results—The patients with SLE had a median age of 45 years with a range of disease duration from 4 years to 18 years; 45.6% were identified as having disease activity. In this sample, we identified a high IFN-γ prevalence of 35.4%. The levels of IFN-γ were higher in the patients with genotype TT than GG. We found that TT genotype conferred a higher risk of high IFN-γ when compared to the GG and GT genotypes. Conclusions—In this study, we identified that the polymorphic genotype TT of the STAT4 gene rs7574865 polymorphism is associated with increased levels of IFN-γ. However, its strength of association was weak, so complementary studies are needed to evaluate its impact on SLE patients.
PeCLH2 Gene Positively Regulate Salt Tolerance in Transgenic Populus alba × Populus glandulosa
Authors: Ge Xiaolan , Du Jiujun , Zhang Lei , Qu Guanzheng , Hu Jianjun
Published: February 2023

Salt is an important environmental stress factor, which seriously affects the growth, development and distribution of plants. Chlorophyllase plays an important role in stress response. Nevertheless, little is known about the physiological and molecular mechanism of chlorophyll (Chlase, CLH) genes in plants. We cloned PeCLH2 from Populus euphratica and found that PeCLH2 was differentially expressed in different tissues, especially in the leaves of P. euphratica. To further study the role of PeCLH2 in salt tolerance, PeCLH2 overexpression and RNA interference transgenic lines were established in Populus alba × Populus glandulosa and used for salt stress treatment and physiologic indexes studies. Overexpressing lines significantly improved tolerance to salt treatment and reduced reactive oxygen species production. RNA interference lines showed the opposite. Transcriptome analysis was performed on leaves of control and transgenic lines under normal growth conditions and salt stress to predict genes regulated during salt stress. This provides a basis for elucidating the molecular regulation mechanism of PeCLH2 in response to salt stress and improving the tolerance of poplar under salt stress.
A Comparative Analysis of the Chloroplast Genomes of Three Lonicera Medicinal Plants
Authors: Yang Chenju , Zhang Ni , Wu Shaoxiong , Jiang Chunyan , Xie Lian , Yang Feng , Yu Zhengwen
Published: February 2023

Both Lonicerae japonicae flos and Lonicerae similis flos are important components in traditional Chinese medicine (TCM) with precious medicinal value. However, the absence of studies on their chloroplast genomes and chromatography has considerably hindered the study of their evolutionary and phylogenetic relationships. In this study, the complete chloroplast (cp) genomes of Lonicera acuminata Wall. and Lonicera similis Hemsl. were sequenced using the Illumina sequencing platform and compared with that of Lonicera japonica Thunb., which has been previously reported. Furthermore, the chromatographic fingerprints of the three plants were constructed using HPLC and the content of quality marker (Q-Marker) was calculated. The annotation results showed that the two chloroplast genomes were typical quadripartite structures with lengths of 155,330 bp (L. acuminata) and 155,207 bp (L. similis). A total of 126 different genes were annotated, containing 82 protein-coding genes, 36 tRNA genes, and 8 rRNA genes. The expansion and contraction of the inverted repeat (IR) regions suggested that the boundary regions of IR/SC were comparatively conserved in the three species, and six regions (trnH-GUG-psbA, rps2-rpoC2, rbcL-psaI, trnN-GUU-ndhF, rps15-ycf1, and infA) with nucleotide diversity values (Pi) of variable sites higher than 1% were identified. Phylogenetic relation indicated that L. similis had a closer genetic relationship with L. japonica than L. acuminata. Additionally, the chromatographic fingerprints showed that the characteristic peaks of the three medicinal plants were similar, including Neochlorogenic acid, Chlorogenic acid, 4-Dicaffeoylquinic acid, Sweroside, Secoxyloganin, Luteoloside, Isochlorogenic acid A, Isochlorogenic acid B, and Isochlorogenic acid C. The content of chlorogenic acid and total phenolic acid in L. acuminata (7.4633 ± 0.4461%, 14.8953 ± 0.0728%) and L. similis (14.1055 ± 0.2566%, 21.9782 ± 0.1331%) was much higher than that of L. japonica (3.9729 ± 0.0928%, 6.0964 ± 0.1228%), respectively. This study provides appropriate information for species identification, phylogeny, quality assessment, and rational use of three medicinal plants of the genus Lonicera.
Editorial of the Special Issue “Seismic Vulnerability and Strengthening of Unreinforced Masonry Buildings”
Authors: Formisano Antonio , Sorrentino Luigi , Zucconi Maria
Published: February 2023

Historical structures represent a significant percentage of existing constructions in numerous seismic-prone regions, and some of these are iconic monuments of their countries [...]
Innovative Non-Pharmacological Management of Delirium in Persons with Dementia: New Frontiers for Physiotherapy and Occupational Therapy?
Authors: Pozzi Christian , Tatzer Verena C. , Strasser-Gugerell Cornelia , Cavalli Stefano , Morandi Alessandro , Bellelli Giuseppe
Published: February 2023

Background: Delirium and dementia are two of the most common geriatric syndromes, which requires innovative rehabilitation approaches. Aim: We aimed at determining which occupational therapy and physiotherapy interventions are applied with older people with delirium and dementia in different care settings. We also identified the assessment tools that were used. Materials and methods: We conducted a literature search for scientific articles published from 2012 to 2022 (PubMed, MEDLINE, AMED and CINAHL) with adults aged >65 years including experimental study designs with randomized or non-randomized intervention, exploratory studies, pilot studies, quasi-experimental studies, case series and/or clinical cases. Studies that did not use interventions that could be classified as occupational therapy or physiotherapy were excluded. Results: After applying the exclusion criteria, 9 articles were selected. The most widely used assessment to define dementia was the MMSE (N = 5; 55.5%), whereas the CAM (N = 2; 22.2%), CAM-ICU (N = 2; 22.2%) and RASS (N = 3; 33.3%) were the most widely used to define delirium. The rehabilitation interventions that were most frequently performed were early mobilization, inclusion of the caregiver during treatment, modification of the environment to encourage orientation and autonomy, the interprofessional systemic approach and engaging persons in meaningful activities. Conclusions: Despite the growing evidence on its effectiveness, the role of physiotherapy and occupational therapy interventions in the prevention and treatment of people with dementia and delirium is still emerging. More research is needed to investigate if effective occupational therapy programs known to reduce the behavioral and psychological symptoms in people with dementia are also useful for treating delirium and specifically delirium superimposed on dementia. Regarding physiotherapy, it is crucial to know about the amount and timing of intervention required. Further studies are needed including older adults with delirium superimposed on dementia to define the role of the interprofessional geriatric rehabilitation team.
Healthcare Resource Utilization in Patients with Newly Diagnosed Atrial Fibrillation: A Global Analysis from the GARFIELD-AF Registry
Authors: Mantovani Lorenzo G. , Cozzolino Paolo , Ferrara Pietro , Virdone Saverio , Camm A. John , Verheugt Freek W. A. , Bassand Jean-Pierre , Turpie Alexander G. G. , Hacke Werner , Kayani Gloria , Goldhaber Samuel Z. , Goto Shinya , Pieper Karen S. , Gersh Bernard J. , Fox Keith A. A. , Haas Sylvia , van Eickels Martin , Kakkar Ajay K. ,   on behalf of the GARFIELD-AF Investigators
Published: February 2023

The management of atrial fibrillation (AF), the most common sustained arrhythmia, impacts healthcare resource utilization (HCRU). This study aims to estimate global resource use in AF patients, using the GARFIELD-AF registry. A prospective cohort study was conducted to characterize HCRU in AF patients enrolled in sequential cohorts from 2012 to 2016 in 35 countries. Components of HCRU studied were hospital admissions, outpatient care visits, and diagnostic and interventional procedures occurring during follow-up. AF-related HCRU was reported as the percentage of patients demonstrating at least one event and was quantified as rate-per-patient-per-year (PPPY) over time. A total of 49,574 patients was analyzed, having an overall median follow-up of 719 days. Almost all patients (99.5%) had at least one outpatient care visit, while hospital admissions were the second most frequent medical contact, with similar proportions in North America (37.5%) and Europe (37.2%), and slightly higher in the other GARFIELD-AF countries (42.0%; namely Australia, Egypt, and South Africa). Asia and Latin America showed lower percentages of hospitalizations, outpatient care visits, and diagnostic and interventional procedures. Analyses of GARFIELD-AF highlighted the vast AF-related HCRU, underlying significant geographical differences in the type, quantity, and frequency of AF-related HCRU. These differences were likely attributable to health service availability and differing models of care.
Psychological Experience of Smoking Addiction in Family and Friends of Schizophrenic Adults Who Smoke Daily: A Qualitative Study
Authors: Caponnetto Pasquale , Maglia Marilena , Gulizia Annalisa , Prezzavento Graziella Chiara , Polosa Riccardo , Quattropani Maria Catena , Signorelli Maria Salvina
Published: February 2023

The smoking addiction of patients with severe mental disorders has consequences not only for the patients but also for the people around them. This is qualitative research on family and friends of patients with Schizophrenia spectrum disorders to investigate their perception and vision of smoking, its impact on the patients’ physical and mental health, and the possible attempts to combat addiction. The research also investigates the participants’ views on electronic cigarettes as a means of replacing traditional cigarettes and helping the patient to quit smoking. The survey method used was a semi-structured interview. The answers were recorded, transcribed and analyzed with the technique of thematic analysis. The results of this study show that the view of most participants on smoking is negative (83.3%), although not all of them consider smoking cessation treatments for these patients of primary importance (33.3%). Nevertheless, a good number of them have tried to intervene spontaneously with their own resources and strategies (66.6%). Finally, low-risk products, and in particular electronic cigarettes, are considered by many participants as a useful alternative to traditional cigarettes in patients with schizophrenia spectrum disorders. About the meaning that cigarettes can assume for the patient, recurring themes emerge: they are considered as a way to manage nervousness and tension or as a means to contrast daily monotony and boredom or repeat usual gestures and habits.
A Participatory Archives Approach to Fostering Connectivity, Increasing Empathy, and Building Resilience during the COVID-19 Pandemic
Authors: Bushey Jessica
Published: February 2023

This paper explores two pandemic-era projects conducted by the Museum and Archives of North Vancouver (MONOVA) using a participatory archives framework during the COVID-19 pandemic. #NorthVanStories, a rapid-respond social media collecting project, ran from May to September 2020 and received over 200 submissions. #NorthVanStories–Living Histories, a digital video oral history project, ran from summer 2020 to fall 2021 and produced five videos with seven storytellers from diverse and vulnerable communities. This paper discusses the power of collaborative documenting, storytelling, and memory-making to foster connectivity, increase empathy, and build resilience. It highlights the benefits of working collaboratively with organizations and communities; successful approaches to planning and outreach activities; the importance of flexibility and sustainability when working with communities in times of crisis; and how to ensure the future relevance of archives by being responsive to contemporary events and community interests.
Perceived Impact of the COVID-19 Pandemic on Playing Golf: A Qualitative Content Analysis Study
Authors: Jungwirth David , Gahbauer Susanne , Haluza Daniela
Published: February 2023

Golf is a very popular outdoor sport played worldwide by people from various socio-economic backgrounds. During the COVID-19 pandemic, lockdowns and quarantine restrictions led to closures of indoor and outdoor sport facilities and thus also affected the access to golf courses. This study aimed at elucidating perceptions of golfers regarding the impact of the crisis on their sport. We surveyed a sample of golfers in German-speaking countries (primarily Austria and Germany) from March to June 2021. A content analysis on golfers’ responses (n = 923) to an open-ended question on their feelings and engagement in alternative ways of physical activity in light of closed sport facilities was performed. More than 23% of the comments concerned negative feelings on how the pandemic impacted the surveyed golfers, especially due to reluctance to accept the closure of outdoor sports facilities. Almost all participants stated to perform alternative outdoor sports, mostly hiking, biking, walking, and running. In times of a pandemic, public spaces should be designed to allow for safe physical activity to maintain a mentally and physically fit population. In this context, policy makers should provide hygiene concepts that allow for minimal disturbance of sport routines, especially in regard to outdoor sports such as golf.
Co-Benefits of China’s Carbon Emissions Trading Scheme: Impact Mechanism and Spillover Effect
Authors: Liu Zijian , Cai Lian , Zhang Yabin
Published: February 2023

Based on the panel data of 281 prefecture-level cities in China, from 2007 to 2017, we empirically explore the co-benefits of the carbon emissions trading scheme. We found that the carbon emissions trading scheme effectively achieved the coordinated control of carbon dioxide and air pollutants, by improving the green production level of the pilot areas, reducing the regional industrial output, and promoting the upgrading of the industrial structure. In terms of heterogeneity, the emissions trading scheme shows obvious urban location and level heterogeneity, in terms of coordinated control. The synergistic emission reduction effects of eastern and central cities are significantly better than those of cities in central and western regions and non-central cities. It has also had positive spillover effects on the surrounding cities of the pilot areas, but pollution levels in farther areas may have increased due to possible “pollution shelter problems”.
Attitudes towards Peers with Disabilities among Schoolchildren in Physical Education Classes
Authors: Rojo-Ramos Jorge , Gomez-Paniagua Santiago , Adsuar Jose Carmelo , Mendoza-Muñoz Maria , Castillo-Paredes Antonio , Denche-Zamorano Angel , Garcia-Gordillo Miguel Angel , Barrios-Fernandez Sabina
Published: February 2023

All children, including those living with disabilities, have the right to be provided with Inclusive Education (IE) together with appropriate support in scholarly settings. A key factor for educational inclusion is peers’ attitudes towards disabilities, which impact disabled students’ social participation and learning. Physical Education (PE) classes represent an opportunity for students with disabilities to get psychological, social, health, and educational benefits. This study aimed to assess Spanish students’ attitudes regarding their peers with disabilities during PE lessons and to explore possible differences between gender, school location, and age group. The sample consisted of 1437 students from public schools in Extremadura (Spain) from the primary and secondary stages. Participants completed the Attitude towards Students with Disabilities in Physical Education (EAADEF-EP) Questionnaire. The Mann-Whitney U test was carried out to establish differences in scores according to sex, school location, age group, and correlations between age and item scores using the Spearman’s Rho test. The results displayed significant differences in the total and item scores considering sex and centre location, with good reliability values (Cronbach’s alpha = 0.86). The EAADEF-EP Questionnaire has proven to be a quick, easy, and inexpensive tool to assess attitudes. Girls and participants whose school was in a rural setting had better attitudes towards inclusion. This study’s results highlight the importance of carrying out educational actions and programs to improve students’ attitudes towards their peers with disabilities considering the influences of the studied variables.
Self-Rated Health as a Predictor of Mortality in Older Adults: A Systematic Review
Authors: Dramé Moustapha , Cantegrit Eléonore , Godaert Lidvine
Published: February 2023

The aim of this study was to investigate the link between self-reported health (SRH) and mortality in older adults. In total, 505 studies were found in PubMed and Scopus, of which 26 were included in this review. In total, 6 of the 26 studies included did not find any evidence of an association between SRH and mortality. Of the 21 studies that included community dwellers, 16 found a significant relationship between SRH and mortality. In total, 17 studies involved patients with no specific medical conditions; among these, 12 found a significant link between SRH and mortality. Among the studies in adults with specific medical conditions, eight showed a significant association between SRH and mortality. Among the 20 studies that definitely included people younger than 80 years, 14 found a significant association between SRH and mortality. Of the twenty-six studies, four examined short-term mortality; seven, medium-term mortality; and eighteen, long-term mortality. Among these, a significant association between SRH and mortality was found in 3, 7, and 12 studies, respectively. This study supports the existence of a significant relation between SRH and mortality. A better understanding of the components of SRH might help guide preventive health policies aimed at delaying mortality in the long term.
Indigenous Eye Health in the Americas: The Burden of Vision Impairment and Ocular Diseases
Authors: Furtado João Marcello , Fernandes Arthur Gustavo , Silva Juan Carlos , Del Pino Sandra , Hommes Carolina
Published: February 2023

Review of the burden of vision impairment and blindness and ocular disease occurrence in Indigenous Peoples of the Americas. We systematically reviewed findings of the frequency of vision impairment and blindness and/or frequency of ocular findings in Indigenous groups. The database search yielded 2829 citations, of which 2747 were excluded. We screened the full texts of 82 records for relevance and excluded 16. The remaining 66 articles were examined thoroughly, and 25 presented sufficient data to be included. Another 7 articles derived from references were included, summing a total of 32 studies selected. When considering adults over 40 years old, the highest frequencies of vision impairment and blindness in Indigenous Peoples varied from 11.1% in high-income North America to 28.5% in tropical Latin America, whose rates are considerably higher than those in the general population. Most of the ocular diseases reported were preventable and/or treatable, so blindness prevention programs should focus on accessibility to eye examinations, cataract surgeries, control of infectious diseases, and spectacles distribution. Finally, we recommend actions in six areas of attention towards improving the eye health in Indigenous Peoples: access and integration of eye services with primary care; telemedicine; customized propaedeutics; education on eye health; and quality of data.
Prevalence of Hearing Loss and Perceptions of Hearing Health and Protection among Florida Firefighters
Authors: Millet Barbara , Snapp Hillary A. , Rajguru Suhrud M. , Schaefer Solle Natasha
Published: February 2023

Firefighters are exposed to extensive hazardous noise while on the job, both during routine tasks at the station and when responding to calls. However, little is known about firefighters’ occupational noise hazards. This study employed mixed methods, including focus groups, a survey, and audiometric testing, to identify sources of noise in the firefighters’ work environment, determine hearing protective strategies, discern firefighters’ perceptions of occupational noise exposure and impacts to their health, and quantify the prevalence of hearing loss among South Florida firefighters. A total of 6 senior officers served in an expert panel, 12 participated in focus groups, 300 completed the survey, and 214 received audiometric tests. Most firefighters were unaware of the risk and their departments’ policies, and did not participate in hearing protection practices and avoided using hearing protection devices, which they believed impede team communication and situational awareness. Nearly 30% of participating firefighters showed mild to profound hearing loss, a prevalence that is considerably worse than expected by normal aging alone. Educating firefighters about noise-induced hearing loss early in their careers may have significant health implications for their future. These findings provide insights for developing technologies and programs to mitigate the effects of noise exposure in the firefighting population.
The Impact of Physical Exercises with Elements of Dance Movement Therapy on Anthropometric Parameters and Physical Fitness among Functionally Limited Older Nursing Home Residents
Authors: Wołoszyn Natalia , Brożonowicz Justyna , Grzegorczyk Joanna , Leszczak Justyna , Kwolek Andrzej , Wiśniowska-Szurlej Agnieszka
Published: February 2023

Changes in the composition of the body mass of functionally limited older patients may contribute to a decrease in functional fitness and the development of chronic diseases. This research aimed to assess the differences in anthropometric parameters and physical fitness of older patients, over the age of 65, in a 12-week clinical intervention study. Method: The study participants were nursing home inhabitants aged 65–85 who were functionally limited. Persons meeting the inclusion criteria were assigned to one of the three groups: Group 1–basic exercises/BE group (n = 56); Group 2—physical exercises with elements of dancing/PED group (n = 57); Group 3—control group/CO group (n = 56) routine care. The data were collected at the beginning of the study and at the 12-week mark. The outcome was observed for hand grip strength (HGS), arm curl test (ACT), Barthel Index (BI), Berg Balance Scale (BBS), triceps skin fold (TSF), waist-to-hip-ratio (WHR), and arm muscle area (AMA). Results: The study included 98 women and 71 men. The average age of the participants was 74.40 years. The analysis of the effects of the 12-week exercise program showed the greatest changes in HGS, ACT, and BI in the exercise groups, especially in the PED group compared to the BE group. Statistically significant differences in the examined parameters of the PED vs. BE vs. CO groups were demonstrated in favour of the exercising groups. In conclusion, a 12-week program of group physical exercises, both PED and BE, improves physical fitness indicators and anthropometric indicators.
Serious Clinical Outcomes of COVID-19 Related to Acetaminophen or NSAIDs from a Nationwide Population-Based Cohort Study
Authors: Kim Jin-Woo , Yoon Siyeong , Lee Jongheon , Lee Soonchul
Published: February 2023

Acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) have been widely prescribed to infected patients; however, the safety of them has not been investigated in patients with serious acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Our objective was to evaluate the association between the previous use of acetaminophen or NSAIDs and the clinical outcomes of SARS-CoV-2 infection. A nationwide population-based cohort study was conducted using the Korean Health Insurance Review and Assessment Database through propensity score matching (PSM). A total of 25,739 patients aged 20 years and older who tested for SARS-CoV-2 were included from 1 January 2015 to 15 May 2020. The primary endpoint was a positive result for a SARS-CoV-2 test, and the secondary endpoint was serious clinical outcomes of SARS-CoV-2 infection, such as conventional oxygen therapy, admission to the intensive care unit, need for invasive ventilation care, or death. Of 1058 patients, after propensity score matching, 176 acetaminophen users and 162 NSAIDs users were diagnosed with coronavirus disease 2019. After PSM, 162 paired data sets were generated, and the clinical outcomes of the acetaminophen group were not significantly different from those of the NSAIDs group. This suggests that acetaminophen and NSAIDs can be used safely to control symptoms in patients suspected of having SARS-CoV-2.
Research on Rural Population/Arable Land/Rural Settlements Association Model and Coordinated Development Path: A Case Analysis of the Yellow River Basin (Henan Section)
Authors: Zhao Suxia , Yin Mengmeng
Published: February 2023

The countryside is a complex regional system with population and land as the core elements, and it is of great significance to study the coordination of the rural human–land relationship for promoting rural ecological protection and high-quality development. The Yellow River Basin (Henan section) is an important grain-producing area with dense population, fertile soil, and rich water resources. Based on the rate of change index and Tapio decoupling model, this study took county-level administrative region as the evaluation unit to explore the characteristics of the spatio-temporal correlation model of rural population/arable land/rural settlements in the Yellow River Basin (Henan section) from 2009 to 2018 and the optimal path of coordinated development. The results show the following: (1) The decrease of rural population, the increase of arable land in a relatively large part of non-central cities, the decrease of arable land in central cities, and the general increase in the area of rural settlements are the most important characteristics of the Yellow River Basin (Henan section) for the change of rural population/arable land/rural settlements. (2) There are spatial agglomeration characteristics of rural population changes, arable land changes, and rural settlements changes. Areas with a high degree of change in arable land have a certain degree of spatial consistency with areas with a high degree of change in rural settlements. (3) The type of T3 (rural population and arable land)/T3 (rural population and rural settlement) is the most important temporal and spatial combination mode, and rural population outflow is serious. In general, the spatio-temporal correlation model of rural population/arable land/rural settlements in the eastern and western sections of the Yellow River Basin (Henan section) is better than that in the middle section. The research results are helpful to deeply understand the relationship between rural population and land in the period of rapid urbanization and can provide reference for the classification and sub-standard policies of rural revitalization. It is urgent to establish sustainable rural development strategies for improving the human–land relationship, narrowing the rural–urban disparity, innovating rural residential land area policies, and revitalizing the rural area.
An Evolving HIV Epidemic in the Middle East and North Africa (MENA) Region: A Scoping Review
Authors: Karbasi Arvin , Fordjuoh Judy , Abbas Mentalla , Iloegbu Chukwuemeka , Patena John , Adenikinju Deborah , Vieira Dorice , Gyamfi Joyce , Peprah Emmanuel
Published: February 2023

Human immunodeficiency virus (HIV) in the Middle East and North Africa (MENA) region is severely understudied despite the region’s increase in new HIV infections since 2010. A key population that is particularly affected, due to the lack of adequate knowledge and proper interventional implementation, includes people who inject drugs (PWID). Furthermore, the paucity of HIV data (prevalence and trends) worsens an already critical situation in this region. A scoping review was conducted to address the scarcity of information and to synthesize the available data on HIV prevalence rates within the key population of PWID throughout the MENA region. Information was sourced from major public health databases and world health reports. Of the 1864 articles screened, 40 studies discussed the various factors contributing to the under-reporting of HIV data in the MENA region among PWID. High and overlapping risk behaviors were cited as the most prevalent reason why HIV trends were incomprehensible and hard to characterize among PWID, followed by lack of service utilization, lack of intervention-based programs, cultural norms, lack of advanced HIV surveillance systems, and protracted humanitarian emergencies. Overall, the lack of reported information limits any adequate response to the growing and unknown HIV trends throughout the region.