bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Sustainable Supply Chain Management in the Construction Industry
Authors: Pervez Arsalan
Published: October 2022

This paper aims to introduce the impact of sustainable supply chain management in the Pakistani construction industry and how it helps with the performance and Development of the construction industry. It aims to elaborate on and emphasize how a sustainable supply chain will be more effective the traditional construction management and its supply chains. A quantitative research method with a deductive approach was used to test research hypotheses. A sample of 154 respondents using a questionnaire responded for data analysis. In Pakistan, the market for a construction company is primarily local based and highly volatile. The assessment is carried out to determine the level of significance and degree of impact of supply chain management (SCM) and sustainability on the construction industry's performance. The results derived from the test show that SCM has a moderate impact leading to leading to increased performance. The lack of time and budget limited the focus to Karachi-based construction businesses, leaving other construction businesses in Pakistan as not relevant. The paper primarily focused on the Pakistan-based construction industry, and the articles that are a source for this study generated knowledge regarding various issues and opportunities associated with supply chain management in the Karachi-based construction industry.
Role of Management in Implementation of Sustainable Supply Chain Management
Authors: Christian Ali
Published: October 2022

Businesses are increasingly focusing on acquiring and delivering products and services that have the least negative impact on planning, execution, and collaboration. As a result of the above, industry and academia have taken an interest in the concept of sustainable supply chain management, owing to its importance in terms of environmental, social, and corporate responsibility, as well as its e-commerce component. The most important theoretical contribution of this research is that it demonstrates that independent factors have a positive impact on organizational growth. Because of commercial concerns, Sustainable Supply is a major issue in the corporate sector. Supply chain management has gotten increased attention since the 1980s when companies began to illustrate the benefits of reciprocal ties in the workplace. As a result, academics are concentrating their efforts on developing new supply chain theories that benefit businesses. The main goals of this study are to provide a written assessment of possible supply chain management based on publications published from 1990 to the present. The moment provides a conceptually plausible supply chain process model based on the triple foot line premise. The results from the study on cost-effective supply chain management don't add up. Most previous studies have focused on the environmental, social, and economic aspects of one could in the supply chain. The majority of previous inquiries were focused on overwhelming conceptual nature. There is a scarcity of research on long-term supply chain management based on extensive observational evidence. This research focuses on the Pakistan supply chain's triple foot line maintainability, taking into planning, execution, collaboration and coordination factors. This consideration also emphasizes the importance of PhD research in this sector in the future.
Impact of Lean Manufacturing on Organizational Performance through a Moderating Role of ERP
Authors: Saleem Gulrez
Published: October 2022

Lean manufacturing is regarded as a rewarding production approach because of its sound effects on organizational and economic efficiency in various sectors. Given the increased environmental consciousness, the environmental successes of lean manufacturing also have significant economic importance. According to some experts, lean manufacturing is a business technique utilized to enhance an organization's process performance. This is because it leads to an increase in both the bottom-line outcomes and customer satisfaction. As a result, many studies have demonstrated that lean manufacturing significantly influences an organization's operational effectiveness. Furthermore, introducing an ERP system brought several benefits in meeting the changing expectations of consumers by delivering accurate and timely information about customers to the company so that they could make adjustments in their choice, respecting the customers' demands. Furthermore, in this study, the researcher discovered the influence of lean manufacturing on organizational performance in connection to the mediating function of ERP. Furthermore, the researcher examined all of the lean manufacturing methods that were interconnected.
Phân tích kinh tế tuần hoàn ở quy mô doanh nghiệp: Trường hợp điển hình tại một công ty bao bì ở Việt Nam
Authors: Nguyễn Hoàng Nam
Published: October 2022

Trong quá chuyển đổi từ kinh tế tuyến tính sang kinh tế tuần hoàn, việc đo lường và theo dõi tính tuần hoàn là rất quan trọng. Nghiên cứu này tổng quan các phương pháp phân tích kinh tế tuần hoàn trong doanh nghiệp và áp dụng thí điểm phân tích chỉ số tuần hoàn vật liệu với một công ty bao bì tại Việt Nam. Kết quả cho thấy chỉ số tuần hoàn vật liệu trung bình của các sản phẩm là ‑0,4989 (< 0), mức tuyến tính. Tuy nhiên, 2 sản phẩm đạt mức tuần hoàn vật liệu dương cho thấy công ty đã bước đầu thực hiện kinh tế tuần hoàn. Đặc biệt, những phân tích sâu về các chỉ số thành phần đã chỉ ra một số cơ hội cải thiện tuần hoàn vật liệu, từ đó tiết kiệm chi phí cho công ty.
Tausendundein Tag
Authors: Krüger Detlef , Schröder Angela
Published: October 2022

Wenn in Deutschland über Bildung diskutiert wird, ist PISA ein geläufiger Begriff. Die Daten der PISA-Studien dokumentieren seit über 20 Jahren die herkunftsbedingte Bildungsungleichheit im deutschen Schulsystem. Die permanente Suche nach neuen Schulkonzepten wird nicht zu mehr Chancengerechtigkeit im formalen Bildungssystem führen. Erforderlich sind demgegenüber Konzepte und Programme zur Unterstützung von Eltern für die frühe Förderung ihrer Kinder.
Präventionspolitik in Deutschland
Authors: Hollederer Alfons
Published: October 2022

Die Soziale Arbeit ist nicht nur unverhältnismäßig stark von Covid-19 betroffen (gewesen), sondern auch Burnout-gefährdet. Die Gesundheitsförderung gewinnt daher für die Soziale Arbeit selbst, aber auch in ihren Praxisfeldern stark an Bedeutung. Die soziallagenbezogene Gesundheitsförderung stellt eine der wichtigsten Zukunftsaufgaben in der Präventionspolitik dar.
Stigmatisierung durch Sprache bei Essstörungserfahrenen
Authors: Hasenöhrl Cäcilia , Pleynert Isabell , Wiegrebe Lena , Wunderer Eva
Published: October 2022

Essstörungs-Erfahrene können Stigmatisierung ausgesetzt sein, das zeigen vielfältige Forschungsbefunde. Kaum untersucht ist jedoch, inwiefern sich dies in der Sprache widerspiegelt. In 17 Interviews schildern Fachkräfte sowie Frauen mit einer Essstörung sprachlich vermittelte Stigmatisierungserfahrungen. Sie beschreiben eine Bagatellisierung der Erkrankung, abwertende Begrifflichkeiten sowie Gleichsetzungen der Person mit ihrem Körpergewicht oder der Essstörung. Impulse für die Arbeit mit Klient:innen mit einer Essstörung werden abgeleitet.
Die Aktionärsklage nach § 148 Aktiengesetz
Authors: Henkel Eva Franziska
Published: October 2022

Eva Franziska Henkel examines how a reform of shareholders’ derivative actions (Section 148 AktG) could bolster the enforcement of shareholders’ liability claims against executive bodies of German stock corporations, and thereby improve overall corporate governance. The study goes beyond a corporate law and comparative law perspective, and also takes empirical and real behavioral science findings into account. With the help of an empirical study the author proves that, at present, this type of litigation has very limited practical relevance in Germany. Based on these findings, the author then takes a look at existing reform proposals, evaluates them and formulates specific new reform proposals.
Der Rechtsanwalt in Portugal
Authors: Pommerening Júlia
Published: October 2022

In a globalised world, practising abroad is becoming more and more attractive also for attorneys. This work offers an overview of Portuguese professional law and provides valuable insights into the requirements and opportunities of practising law in Portugal and other Portuguese-speaking countries overseas. It addresses all essential requirements of the law concerning the legal profession in Portugal - from the basic prerequisites for practising as an attorney and the possibilities for foreign professionals to establish themselves in Portugal, to the various professional duties and the possibilities for cooperation with other professionals, to the liability of attorneys and the disciplinary sanctioning of breaches of duty.
Sprache und Konfession in Fürstentestamenten des Konfessionellen Zeitalters (1555–1648)
Authors: Krokowski Tim
Published: October 2022

Based on a corpus of twelve wills of Catholic, Lutheran, and Calvinist sovereigns of three territories of the Holy Roman Empire from the period of the Confessional Age, this study investigates the influence of the confession of the testator princes on the use of language in their wills. For this purpose, three different linguistic levels (text structure, authority references, graphy) are taken into consideration. In order to classify the linguistic results, the socio-cultural background of the texts is also taken into account by using the tools of the historical pragmatics. In the appendix of the thesis the transcripts of the wills are made available for further research.
Just Ask about Diversity: A New Librarian Uses Books to Teach Empathy
Authors: Conner Stephanie
Published: October 2022

As a beginning librarian and MLS student, the phrases “on-the-job-training” and “trial by fire” took on new meaning for me. There was so much I had to learn by doing.Soon after starting my library science program at East Carolina University, I accepted a media coordinator position at Lillington-Shawtown (NC) Elementary School, a moderate-sized public school in a small rural county. The pre-kindergarten through fifth grade school had a population of about seven hundred students.
The Importance of Wishes: An Interview with Author Sandra Magsamen
Authors: McChesney Elizabeth
Published: October 2022

Children’s author and illustrator Sandra Magsamen holds a beloved place in the hearts of library professionals who know the impact and power of her loving board and picture books. As the author and illustrator of more than sixty children’s and adult books, Magsamen, trained as an art therapist, hopes to create books that offer people a way to reach out and connect in a meaningful and expressive way with someone in their life, and indeed she accomplishes this with her endearing new release, I Wish Wish Wish for You.
Research Roundup: Placemaking: Expanding Our Reach and Empowering Communities
Authors: Yazdian Lisa M. Sensale , Diamant-Cohen Betsy , Prendergast Tess
Published: October 2022

Due to COVID, communities across the globe have had to rethink ways to safely connect and engage with one another. One option that has emerged is placemaking, “a collaborative process of people coming together to create the great public spaces at the heart of their communities.”Rooted in urban design, placemaking has enabled some communities to successfully negotiate COVID challenges while participating in a process that also has the potential to transform our post-pandemic world. Because 80 percent of children’s time is spent outside of school, it is exceptionally important for communities to leverage opportunities for them to learn beyond classroom walls. Libraries and other community partners can share placemaking resources while exploring new ways to harness placemaking principles to create better social, cultural, and economic outcomes. This is important since many of today’s youth and families are living in inequitable spaces.
The geodetic monitoring of deformations of a high-rise building using ground-based laser scanning technology
Authors: Madimarova Gulmira , Suleimenova Diana , Pentayev Toleubek , Khalykov Yerkebulan , Baydauletova Gulban , Tumazhanova Saltanat , Stankova Hana
Published: October 2022

The article justifies the use of laser-scanning systems for geodetic monitoring of high-rise buildings and structures. Contemporary methods allow solving comprehensively the main tasks of geodetic monitoring. During the monitoring of high-rise objects, not only the main geometric parameters of the objects should be taken into account. The main importance should be given to the mutual arrangement of individual building elements, which is especially important for identifying and predicting deformation processes. Laser scanning coordinate measuring systems are designed to measure the object coordinate points to determine the object's geometric dimensions. The principle of GLS operation is to measure the point coordinates in space by the polar method. Distance is measured by a laser rangefinder using a pulse method with signal digitization technology. The advantage of this approach is a smaller amount of time spent on the creation of a primary survey network. At that, the laying of scanner ray paths is most effective when carrying out ground-based laser scanning of linear structures. But it is advisable to apply its construction elements within the framework of the developed methodology. The development and implementation of new technologies for geodetic work performance, supported by an appropriate level of automation, is always carried out to reduce the time required for data collection and processing. The RiSCAN PRO program is a project-oriented product, i.e. the entire volume of data obtained as a part of a single measurement project is structured and stored according to the RiSCAN PRO project structure.
GT traje de cena, traje de folguedo
Authors: Moura Carolina Bassi de , Viana Fausto Roberto Poço
Published: October 2022

Entrevista concedida em 14 de junho de 2022, em São Paulo e Rio de Janeiro.
Monitoring dynamiki ruchów powierzchni osuwisk w warunkach zmiennego poziomu wód gruntowych z wykorzystaniem reflektorów radarowych
Authors: Perski Zbigniew , Wojciechowski Tomasz
Published: October 2022

The main objective of the presented analysis was to investigate to what extent even minor changes in the hydrological and hydrogeological environment affect the changes in thedynamicsoflandslidesurfacedisplacement.Theresearchwascarriedoutforselectedmonitored landslides, which, in addition to the in-depth monitoring devices, were equipped with corner reflectors suitable for satellite radar interferometry measurements. The high temporal resolution of the interferometric data allowed demonstrating the existence of a relationship between the speed of surface movements and slight changes in the depth to the groundwater table. The analyses were performed for five landslides, which also showed a high dependence of these compounds on the geological structure of the landslide and its substrate.
A new route to the nucleus
Authors: Bao Hongyu , Huang Hongda
Published: October 2022

A newly discovered pathway suggests histone proteins H3 and H4 are imported into the nucleus as individual units rather than joined together as heterodimers as was previously thought.
Impact of ventilator settings during venovenous extracorporeal membrane oxygenation on clinical outcomes in influenza-associated acute respiratory distress syndrome: a multicenter retrospective cohort study
Authors: Liao Ting-Yu , Ruan Sheng-Yuan , Lai Chien-Heng , Tseng Li-Jung , Keng Li-Ta , Chen You-Yi , Wang Chih-Hsien , Chien Jung-Yien , Wu Huey-Dong , Chen Yih-Sharng , Yu Chong-Jen ,   TACTICS Study Group
Published: October 2022

Background

Patients with influenza-associated acute respiratory distress syndrome (ARDS) requiring venovenous extracorporeal membrane oxygenation (vv-ECMO) support have a high mortality rate. Ventilator settings have been known to have a substantial impact on outcomes. However, the optimal settings of mechanical ventilation during vv-ECMO are still unknown.

Methods

This multicenter retrospective cohort study was conducted in the intensive care units (ICUs) of three tertiary referral hospitals in Taiwan between July 2009 and December 2019. It aims to describe the effect of ventilator settings during vv-ECMO on patient outcomes.

Results

A total of 93 patients with influenza receiving ECMO were screened. Patients were excluded if they: were receiving venoarterial ECMO, died within three days of vv-ECMO initiation, or were transferred to the tertiary referral hospital >24 hours after vv-ECMO initiation. A total of 62 patients were included in the study, and 24 (39%) died within six months. During the first three days of ECMO, there were no differences in tidal volume (5.1 vs. 5.2 mL/kg, p = 0.833), dynamic driving pressure (15 vs. 14 cmH2O, p = 0.146), and mechanical power (11.3 vs. 11.8 J/min, p = 0.352) between survivors and non-survivors. However, respiratory rates were significantly higher in non-survivors compared with survivors (15 vs. 12 breaths/min, p = 0.013). After adjustment for important confounders, a higher mean respiratory rate of >12 breaths/min was still associated with higher mortality (adjusted hazard ratio = 3.31, 95% confidence interval = 1.10–9.97, p = 0.034).

Conclusions

In patients with influenza-associated ARDS receiving vv-ECMO support, we found that a higher respiratory rate was associated with higher mortality. Respiratory rate might be a modifiable factor to improve outcomes in this patient population.
Effect of Consanguinity on the Audio Profile Section of Non Syndromic Sensorineural Hearing Impaired Children: A Cross-sectional Study
Authors: Gangadhara KS , Bhaktha Geetha , Manjula B , Nirupama S
Published: October 2022

Introduction: The incidence of bilateral sensorineural hearing loss is quite notable in live births worldwide. Among the etiologies, the primary aetiology is thought to be genetic, followed by non heritable, and unknown. Aim: To study the effect of consanguinity on audiological profile in children presented with non syndromic sensorineural hearing loss. Materials And Methods: This cross-sectional study was conducted in the Department of Ear Nose Throat, McGANN Teaching District Hospital (Shimoga Institute of Medical Sciences), Shivamogga, Karnataka, India, from January 2019 to December 2020, among 95 children with non syndromic sensorineural hearing loss. A Pure Tone Audiometry (PTA) test was done for each patient both air conduction and bone conduction thresholds were tested using different transducers. An audiogram was collected and the degree of hearing loss of each patient was analysed. Statistical tests were performed using Statistical Package for Social Sciences (SPSS) version 34.0, Kruskal-Wallis test, oneway Analysis of Variance (ANOVA) was used for comparing the difference in PTA followed by the Mann-Whitney U test. Results: The mean age of the study population was 9.7 years; 39 subjects were female, and 56 were male. The PTA among the study population showed asymmetric audiograms in 17 (17.9%) children. A majority (60, 63%) of the participants were born out of consanguineous marriage. Total 80 (84.2%) children had bilateral hearing loss, among which 58 (72.5%) were cases of bilateral profound. One-way ANOVA showed that there was an overall significant difference between the consanguinity and non consanguinity groups and post-hoc analysis with the Mann-Whitney U test revealed a significant difference between the different degrees of consanguineous marriage. Conclusion: Consanguinity affects the audio profile (PTA) among the non syndromic hearing-impaired children.
Assessment of Performance in Cognitive vs Affective Domain among First Year MBBS Students: A Cross-sectional Study
Authors: Aristotle Sharmila , Ramraj Balaji
Published: October 2022

Introduction: National Medical Commission (NMC) has revised MBBS curriculum and incorporated Competency Based Medical Curriculum (CBME) which describes various competencies. Most of the competencies are based on cognitive, psychomotor and affective domain, which an Indian medical graduate should attain. Both cognitive and psychomotor domains were taught as a part of curriculum however, students learned affective domain as a hidden curriculum only. Now CBME has incorporated affective domain as a part of MBBS curriculum in the form of Attitudes Ethics and Communication (AETCOM) module, teaching and evaluating the affective domain demands attention. Aim: To evaluate the performance of first year MBBS students in cognitive domain vs affective domain from their routine curriculum. Materials and Methods: This cross-sectional study was conducted in SRM Medical college Hospital and research center from September 2019 to October 2019 among 149 1st year MBBS students. Three students were absent on day of assessment. Hence, 146 students were assessed in both domains. The performance of both domains (cognitive and affective) were assessed in the form of Objective Structured Practical Examination (OSPE). Chi-square was used to compare the qualitative data and Unpaired t-test was used to compare the means. Results: The mean age of the students was 18.66±0.64 years. About 76 (52.1%) were male and 70 (47.9%) were female students. Out of total, 22 (15.1%) of students had scored less than minimum mark for pass in cognitive and 8 (5.5%) of students had scored less than minimum mark for pass in AETCOM. Only 2 (1.3%) of students had scored less than minimum mark for pass in both OSPE examinations. In addition, 49 (33.5%) students had scored more than average marks in cognitive and 94 (64.4%) students had scored more than average in AETCOM and 34 (22.8%) of students had scored more than average in both domains. The difference in the mean score was found to be statistically significant (p-value<0.0001). Conclusion: This study concludes that the learners performed better in affective domain, when compared to cognitive domain.
Design and Development of a 3D Printable Neck Brace- A Finite Element Approach
Authors: Babu R Dhanush , Veezhinathan Mahesh , Adithya S Siva , Jagadeesan Nandhini
Published: October 2022

Introduction: Neck braces are commonly used to immobilise and support the neck and spinal cord. Even though neck brace has given significant assistance for proper management of cervical spine injuries, it offers a false sense of security where it might prevent additional and further spinal cord injury. Customised neck brace can provide additional comfort. Furthermore, doctor’s views and opinions were taken into consideration and the design has been altered and also can be made customisable to suit every patient, ensuring their comfort at the same time. Aim: To design a 3D printable neck brace and to evaluate it numerically by means of Finite Element Modelling (FEM). Materials and Methods: The model was designed in Autodesk Fusion 360 software and then was imported into HyperWorks for further analysis. Polylactic Acid (PLA) was assigned as a material to the model and it was analysed under two conditions after assignment of materials properties such as young’s modulus, density and Poisson’s ratio. HyperView was utilised to visualise the results of the linear static analysis to further enhance the model. Results: The maximum displacement, stress and strain of the model was observed in the posterior and interior segments which was found to be 1.813E-06, 1.109E+0, 4.805E-02 respectively upon application of a force of 20 N and 1.656E-06, 1.202E+03, 2.286E-07 respectively when a force of 100 N was applied. Conclusion: The study found varying stress, strain and displacement values upon application of an external force which was used in the evaluation of the model. It was also found that PLA material led to better alignment and strength of the overall model and a mixture of PLA and natural rubber can be used as a viable 3D printing filament.
IMPACT OF ADHESIVE TYPE AND ABRASIVE WEAR USED IN THE SURFACE PREPARATION PROCESS ON THE STRENGTH OF STEEL SHEET ADHESIVE JOINTS
Authors:   Lublin University of Technology, Miturska-Barańska Izabela , Rudawska Anna , Doluk Elżbieta , Ogrodniczek Jacek
Published: October 2022

The aim of the paper was to present issues related to the determination of the influence of selected technological factors: the method of surface preparation and type of adhesive on the strength of adhesive joints made of steel sheet C45. As a method of surface preparation the process of shot-blasting with the use of three types of abrasives differentiated in terms of the degree of its wear was used. The adhesive bonds were made with the use of two two-component epoxy adhesive compositions based on Epidian 57 epoxy resin and PAC and Z-1 curing agents combined with the resin in the recommended proportions. The measurements of roughness and topography of surfaces prepared for the bonding process were also carried out. After the curing process, strength tests of adhesive bonds were performed on the Zwick/Roell 150 testing machine, according to PN-EN 1465 standard. It was noted, among others, that with increasing wear of the abrasive used in the surface preparation process, the value of adhesive bonds strength decreased and the higher strength of adhesive bonds was characterized by adhesive joints made with Epidian57/Z-1/100:10 adhesive. The obtained results were subjected to statistical analysis.
Study on the Qualitative Characteristics of Superior Cultivars of Litchi Fruits in Jorhat, Assam
Authors: Saikia Pansurika , Kotoky Utpal
Published: October 2022

The present experiment was carried on five superior cultivars of litchi fruit in the Department of Horticulture in Assam Agricultural University, Jorhat, Assam during 2020-2021. All the biochemical parameters studied under this experiment were found to be significant in character. Generally, in most of the biochemical parameters, the cultivar Bilati recorded the highest among all, such as in juice content (13.62cc), reducing sugar (8.37%), invert sugar (17.44%), sucrose (8.60%), total sugar (16.99%), sugar-acid ratio (40.71), potassium (1263.75mg/100g), vitamin C (62.11mg/100g), anthocyanin content (38.41mg/100g) and colour density (3.87) while in Titratable acidity, Anthocyanin degradation and polymery colour recorded to be the lowest. Thus, it was concluded that the cultivar Bilati turned out to be the most superior one among all the rest cultivars in terms of biochemical characteristics.
Tropospheric Influence on Low-band Very High Frequency (VHF) Radio Waves
Authors: Ekah Ukoette Jeremiah , Obi Emmanuel , Ewona Igwe
Published: October 2022

The objectives of this study are to understudy the effects of temperature and relative humidity on low-band VHF signals, obtain a propagation model for signal transmission over Calabar and to ascertain the suitability of the free space propagation model for the study terrain. Results obtained shows that temperature and relative humidity has no effect on low-band VHF signals. The suitability of the free space propagation model for the study terrain failed, as calculated results underestimated path losses in the study area. Multiple regression analysis was used to obtain a suitable propagation model for the study terrain. However, since the studied meteorological variables has no effect on low-band VHF signals in the study area, the measured path losses could be attributed to foliage, hills, distance away from the transmitter and other components of the study terrain in which the signal is propagated.
Nephro-protective Efficacy of African Locust Bean Seed against Potassium Bromate-induced Renal Damage
Authors: Abali I. O. , Chika-Igwenyi N. M. , Agu F. U. , Onyeaghala C. A. , Orji S. F. , Ugwu C. N. , Igwenyi C. , Uche C. L. , Onyekachi O. I. N. , Nwobodo M. U. , Iwuoha C. E. , Airaodion A. I.
Published: October 2022

Background: Potassium bromate (KBrO3) has been utilized extensively to sterilize water, dye hair, oxidize food, add to bread dough as a maturing agent, and condition wheat dough, thereby entering into human body. It has been claimed to cause a number of toxicities including nephrotoxicity.

Aim: This study, therefore, sought to investigate the nephro-protective efficacy of African locust bean (ALB) seed against potassium bromate-induced renal damage.

Methodology: Using a soxhlet extractor with ethanol as the solvent, ALB was extracted. Twenty-four mature male Wistar rats were randomly divided into groups A, B, C, and D after being acclimated in the lab. Oral distilled water was administered to Group A. Although groups C and D likewise received 100 and 200 mg/kg body weight of ALB, respectively, the animals in groups B, C, and D received 100 mg/kg body weight of potassium bromate. Rats received daily doses of freshly produced potassium bromate and ALB extract by oral gavage. Blood and kidney sample were taken after the prescribed 28-day course of medication. Standard techniques were used to assess renal biomarkers.

Results: When compared to the control group, potassium bromate treatment led to significant (P<0.05) increases in the serum levels of creatinine, urea, uric acid, sodium (Na+), potassium (K+), chloride (Cl–), and bicarbonate (HCO3–). Renal levels of tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) were likewise elevated by KBrO3 poisoning in comparison to the control group. However, combined administration of KBrO3 and ALB seed extract resulted in significant dose-dependent reductions in the levels of all kidney biomarkers examined, with 200 mg/kg being the most effective dose.

Conclusion: This study revealed that potassium bromate indeed induced nephrotoxicity by unhinging renal biomarkers investigated in this study. It was further observed that seed extract of African locust bean (ALB) alleviated these adverse effects on the kidney by resisting the perturbations, thereby exhibiting nephron-protective effect. The biochemical composition of ALB has conferred it with this ability.
Economically Important Wild Edible Mushrooms of Bonai Forest Division, Odisha, India
Authors: Kumar Sanjeet , Mishra Arun Kumar , N. Sanath Kumar , Mishra Sweta
Published: October 2022

Bonai Forest Division is rich in flora and faunal species. The fertile forest-dominated areas provide a good platform for growing wild mushrooms. The locals collect them for food, medicine, and economic purposes. Addressing the economic value of wild mushrooms will provide a platform for value addition and management of forest & wildlife in Bonai Forest Division, Odisha. Considering the importance of wild mushrooms in the day-to-day lives of tribal communities of the division, an attempt has been made to enumerate the mushrooms having economic values. A survey was carried out during 2021-2022 in 7 ranges. 15 wild mushrooms were identified as having economic value. Rugda mushrooms are the most popular of the 15, and can be sold for up to Rs. 1800 per kg. The present study brings attention to the urgent need for value additions to these mushrooms for the sustainable development of the local communities.
Techno Economic Benefits through Cluster Frontline Demonstrations of Redgram in Mahbubnagar District of Telangana
Authors: Bhatt P. Spandana , Reddy M. Jagan Mohan , Sireesha D.
Published: October 2022

Redgram is the suitable pulse crop for the Mahbubnagar district of Telangana. The farmers are reaping poor yields and lesser net returns as they were nor aware of newly released medium duration Redgram varieties and not practicing the best management practices, keeping in view, Cluster front line demonstration in Redgram were organised in Mahbubnagar district of Telangana state using recent released variety PRG 176 (Ujwala). A total of 50 Front Line demonstrations were organized in cluster approach. Best management practices for Redgram production were demonstrated for getting higher net returns. The demonstrated variety PRG 176 having yield potential of 20 q/ha in light soils recorded average yield of 15.4 q/ha in demonstration field. The check variety recorded an average of 10.9 q/ha. The average gross cost, gross returns, net returns and benefit cost ratio recorded was Rs. 20,000/ha, 83430/ha, 63430/ha and 3.17 than the farmer practice Rs.21000/ha, Rs.67500/ha, Rs.46500 and 2.21 respectively. Cluster front line demonstration is one of the successful extension methods for the transfer of technology to reduce extension gap and adoption gap.
An Aquaponic System with Hydroponic Culture of Sweet Potato and Tilapia Culture
Authors: Islam A. F. M. Saiful , Hirai Hiroaki , Kitaya Yoshiaki
Published: October 2022

An integrated system with a hydroponic culture of sweet potato and tilapia culture was assessed as a new combination in aquaponics to investigate its potential and productivity. The first experiment was conducted inside a glasshouse using plastic tanks as water reservoirs to compare the growth and development of two sweet potato (Ipomoea batatas (L.) Lam.) varieties Beniazuma and purple sweet lord using hydroballs, granular plastics, cut rockwool, and rockwool blocks as supporting materials in hydroponic culture. The supporting material was placed inside plastic pots. Greater growth and development of the storage roots of sweet potatoes in both varieties were obtained in hydroballs. In the second experiment, four sweet potato varieties, Kokei 14, Suioh, Beniazuma, and Elegant summer, with hydroballs as the supporting material, were examined hydroponically with an integrated culture of tilapia fish in the pond. Two ponds were 7.7 m and 5.3 m, in length and width, respectively, and water depth was maintained at 0.38 cm. Styrofoam boxes with holes on the bottom side were used to culture sweet potato on the water surface. Nylon net containers filled with hydroballs were placed in the Styrofoam boxes. The variety Kokei 14 produced the greatest fresh and dry weights of storage roots and percent harvest index in both ponds, with and without fish. The number and diameter of the storage roots of Kokei 14 were higher. Tilapia fish were cultured in one of the two ponds and fed artificial feed. The average length and weight of tilapia fishes increased to 10 cm and 188 g, respectively, 143 days after culturing, and those were 1.8 and 6.9 times, respectively, greater than at the start. The integrated culture of sweet potato hydroponically on the water surface and tilapia in pond water increases the food production in a limited space and profitable.
Cost-effectiveness analysis of leukocyte counters for diagnosis in SUS / Análise de custo-efetividade de contadores de leucócitos para diagnóstico no SUS
Authors: Thuin Rawlson Raoult de , Peregrino Antônio Augusto de Freitas , Cola Carlos Bernardo , Brito Nayra Castelano , Maldonado Thatiara Lares Ferraz , Silva Roberto Carlos Lyra da
Published: October 2022

Objetivo: avaliar o custo-efetividade de analisadores de leucócitos do tipo ponto de atendimento para o auxílio diagnóstico de infecções de vias aéreas no SUS. Método: trata de um estudo de custo-efetividade usando modelo determinístico desenvolvido a partir de uma árvore de decisão. Resultados: o uso de dispositivos para a realização de testes diagnósticos em ponto de tratamento tem se tornado cada vez mais popular e aceito em todo o mundo diante do aumento da demanda de atendimentos e da necessidade de redução do tempo de retorno dos resultados dos exames para otimização dos desfechos. Após o Roll Back da árvore de decisão, a estratégia mais custo-efetiva foi a de investigação clínica orientada por contagem de leucócitos utilizando o analisador de ponto de atendimento para orientar a prescrição de antibióticos. Conclusão: as evidências sugerem que o uso de analisadores POC para contagem de leucócitos e diferenciais no local de atendimento é uma alternativa custo-efetivo como parte de uma estratégia para auxiliar no diagnóstico e no manejo terapêutico dos casos de infeções respiratórias agudas inespecíficas.
Clinical Trial Enrollment, Ineligibility, and Reasons for Decline in Older vs Younger Patients With Cancer in the National Cancer Institute Community Oncology Research Program
Authors: Sedrak Mina S. , Ji Jingran , Tiwari Abhay , Mohile Supriya G. , Dale William , Le-Rademacher Jennifer G.
Published: October 2022

This cross-sectional study assesses differences in clinical trial participation among older vs younger adults with cancer.
The Continued Rise of Unintentional Ingestion of Edible Cannabis in Toddlers—A Growing Public Health Concern
Authors: Van Oyen Alexandra , Perlman Elise , Su Mark K.
Published: October 2022

This Viewpoint discusses the critical need for research regarding perceptions of edible cannabis, effective methods to educate and screen caregivers, and innovative approaches to safe storage, considering the increase in unintentional ingestion of cannabis edibles among children.
Comparison of setup accuracy and efficiency between the Klarity system and BodyFIX system for spine stereotactic body radiation therapy
Authors: Quan Enzhuo , Krafft Shane P. , Briere Tina M. , Vaccarelli Marissa J. , Ghia Amol J. , Bishop Andrew J. , Yeboa Debra N. , Swanson Todd A. , Han Eun Young
Published: October 2022

Background

Spine stereotactic body radiation therapy (SBRT) uses highly conformal dose distributions and sharp dose gradients to cover targets in proximity to the spinal cord or cauda equina, which requires precise patient positioning and immobilization to deliver safe treatments.

Aims

Given some limitations with the BodyFIX system in our practice, we sought to evaluate the accuracy and efficiency of the Klarity SBRT patient immobilization system in comparison to the BodyFIX system.

Methods

Twenty‐three patients with 26 metastatic spinal lesions (78 fractions) were enrolled in this prospective observational study with one of two systems – BodyFIX (n = 11) or Klarity (n = 12). All patients were initially set up to external marks and positioned to match bony anatomy on ExacTrac images. Table corrections given by ExacTrac during setup and intrafractional monitoring and deviations from pre‐ and posttreatment CBCT images were analyzed.

Results

For initial setup accuracy, the Klarity system showed larger differences between initial skin mark alignment and the first bony alignment on ExacTrac than BodyFIX, especially in the vertical (mean [SD] of 5.7 mm [4.1 mm] for Klarity vs. 1.9 mm [1.7 mm] for BodyFIX, p‐value < 0.01) and lateral (5.4 mm [5.1 mm] for Klarity vs. 3.2 mm [3.2 mm] for BodyFIX, p‐value 0.02) directions. For set‐up stability, no significant differences (all p‐values > 0.05) were observed in the maximum magnitude of positional deviations between the two systems. For setup efficiency, Klarity system achieved desired bony alignment with similar number of setup images and similar setup time (14.4 min vs. 15.8 min, p‐value = 0.41). For geometric uncertainty, systematic and random errors were found to be slightly less with Klarity than with BodyFIX based on an analytical calculation.

Conclusion

With image‐guided correction of initial alignment by external marks, the Klarity system can provide accurate and efficient patient immobilization. It can be a promising alternative to the BodyFIX system for spine SBRT while providing potential workflow benefits depending on one's practice environment.
Enhanced Tumor Accumulation of Multimodal Magneto‐Plasmonic Nanoparticles via an Implanted Micromagnet‐Assisted Delivery Strategy
Authors: Panikkanvalappil Sajanlal R. , Bhagavatula Sharath K. , Deans Kyle , Jonas Oliver , Rashidian Mohammad , Mishra Shruti
Published: October 2022

One of the major shortcomings of nano carriers‐assisted cancer therapeutic strategies continues to be the inadequate tumor penetration and retention of systemically administered nanoformulations and its off‐target toxicity. Stromal parameters‐related heterogeneity in enhanced permeability and retention effect and physicochemical properties of the nanoformulations immensely contributes to their poor tumor extravasation. Herein, a novel tumor targeting strategy, where an intratumorally implanted micromagnet can significantly enhance accumulation of magneto‐plasmonic nanoparticles (NPs) at the micromagnet‐implanted tumor in bilateral colorectal tumor models while limiting their off‐target accumulation, is demonstrated. To this end, novel multimodal gold/iron oxide NPs comprised of an array of multifunctional moieties with high therapeutic, sensing, and imaging potential are developed. It is also discovered that cancer cell targeted NPs in combination with static magnetic field can selectively induce cancer cell death. A multimodal caspase‐3 nanosensor is also developed for real‐time visualization of selective induction of apoptosis in cancer cells. In addition, the photothermal killing capability of these NPs in vitro is evaluated, and their potential for enhanced photothermal ablation in tissue samples is demonstrated. Building on current uses of implantable devices for therapeutic purposes, this study envisions the proposed micromagnet‐assisted NPs delivery approach may be used to accelerate the clinical translation of various nanoformulations.
Quantification of the Electromechanical Measurements by Piezoresponse Force Microscopy
Authors: Buragohain Pratyush , Lu Haidong , Richter Claudia , Schenk Tony , Kariuki Pamenas , Glinsek Sebastjan , Funakubo Hiroshi , Íñiguez Jorge , Defay Emmanuel , Schroeder Uwe , Gruverman Alexei
Published: October 2022

Piezoresponse force microscopy (PFM) is widely used for characterization and exploration of the nanoscale properties of ferroelectrics. However, quantification of the PFM signal is challenging due to the convolution of various extrinsic and intrinsic contributions. Although quantification of the PFM amplitude signal has received considerable attention, quantification of the PFM phase signal has not been addressed. A properly calibrated PFM phase signal can provide valuable information on the sign of the local piezoelectric coefficient—an important and nontrivial issue for emerging ferroelectrics. In this work, two complementary methodologies to calibrate the PFM phase signal are discussed. The first approach is based on using a standard reference sample with well‐known independently measured piezoelectric coefficients, while the second approach exploits the electrostatic sample–cantilever interactions to determine the parasitic phase offset. Application of these methodologies to studies of the piezoelectric behavior in ferroelectric HfO2‐based thin‐film capacitors reveals intriguing variations in the sign of the longitudinal piezoelectric coefficient, d33,eff. It is shown that the piezoelectric properties of the HfO2‐based capacitors are inherently sensitive to their thickness, electrodes, as well as deposition methods, and can exhibit wide variations including a d33,eff sign change within a single device.
Community engagement, greening, and violent crime: A test of the greening hypothesis and Busy Streets
Authors: Gong Catherine H. , Bushman Gregory , Hohl Bernadette C. , Kondo Michelle C. , Carter Patrick M. , Cunningham Rebecca M. , Rupp Laney A. , Grodzinski Alison , Branas Charles C. , Vagi Kevin J. , Zimmerman Marc A.
Published: October 2022

Researchers have documented that vacant lot greening can reduce community‐level crime and violence. Busy Streets Theory (BST) suggests that residents who are involved in the greening process can help to improve physical environments and build social connections that deter crime and violence. Yet few researchers have explored how community engagement in the greening process may affect crime and violence outcomes. We applied BST to test the effects of community‐engaged vacant lot greening compared to vacant lots that received either professional mowing or no treatment, on the density of violent crime around study lots. Using mixed effects regression models, we analyzed trends in violent crime density over the summer months from 2016 to 2018 at 2102 street segments in Youngstown, OH. These street segments fell within 150 meters of an intervention parcel that was classified as one of three conditions: community‐engaged maintenance, professional mowing, or no treatment (control). We found that street segments in areas receiving community‐engaged maintenance or professional mowing experienced greater declines in violent crime density than street segments in areas receiving no treatment, and more decline occurred in the community‐engaged condition compared to the professional mow condition. Our findings support BST and suggest that community‐engaged greening of vacant lots in postindustrial cities with a concentrated vacancy can reduce crime and violence.
Substrate Induced Movement of the Metal Cofactor between Active and Resting State
Authors: Marsden Stefan R. , Wijma Hein J. , Mohr Michael K. F. , Justo Inês , Hagedoorn Peter‐Leon , Laustsen Jesper , Jeffries Cy M. , Svergun Dmitri , Mestrom Luuk , McMillan Duncan G. G. , Bento Isabel , Hanefeld Ulf
Published: October 2022

Regulation of enzyme activity is vital for living organisms. In metalloenzymes, far‐reaching rearrangements of the protein scaffold are generally required to tune the metal cofactor's properties by allosteric regulation. Here structural analysis of hydroxyketoacid aldolase from Sphingomonas wittichii RW1 (SwHKA) revealed a dynamic movement of the metal cofactor between two coordination spheres without protein scaffold rearrangements. In its resting state configuration (M2+R), the metal constitutes an integral part of the dimer interface within the overall hexameric assembly, but sterical constraints do not allow for substrate binding. Conversely, a second coordination sphere constitutes the catalytically active state (M2+A) at 2.4 Å distance. Bidentate coordination of a ketoacid substrate to M2+A affords the overall lowest energy complex, which drives the transition from M2+R to M2+A. While not described earlier, this type of regulation may be widespread and largely overlooked due to low occupancy of some of its states in protein crystal structures.
Oxidative stability of high oleic palm and hazelnut skin oil blends
Authors: Akpinar Merve , Bauer Estrada Katherine , Tekin Aziz , Quintanilla‐Carvajal Maria Ximena , Gumus‐Bonacina Cansu Ekin
Published: October 2022

High oleic palm oil (HOPO) with high oleic and palmitic acid contents is a new vegetable oil that needs to find further use in food applications, while hazelnut skin oil (HSO) with high oleic acid content is a by‐product of hazelnut oil production and have no commercial value. The aim of the study was to obtain new oil blends for new food formulations with high oxidative stability and low (or reasonable) saturated fatty acid content using HOPO and HSO. For this aim, they were blended in the proportions of 0 to 100% (wt/wt), and fatty acid and tocol compositions, induction period and storage stability of the blends were evaluated. Tocotrienols (560.94 mg/kg) constitute the majority of the tocol content of HOPO, while tocopherols (437.69 mg/kg) were the major tocols of HSO. HOPO has a higher saturated fatty acid composition and lower monounsaturated fatty acids content than HSO. In general, it was determined that increasing the HSO ratio in oil blends reduced their oxidative stabilities, which is most likely because HSO is richer in total unsaturated fatty acids (91.8%) than HOPO (68.4%). In addition, tocotrienols are known to be stronger antioxidants than tocopherols. Although HOPO is rich in γ‐tocotrienol, which has a strong antioxidant activity, it also has some disadvantages such as having a high price and containing significant levels of saturated fatty acids (mainly palmitic acid). The optimum blend ratio was then determined as 50% HOPO:50% HSO considering oxidative stability and fatty acid compositions.