bluuebunny/crossref_metadata_2025 huggingface dataset:
A Case Study of Organizational and Curricular Attributes for Interprofessional Education: A Model for Sustainable Curriculum Delivery
Authors: Azzam Mohammad , Drynan Donna , Fricke Moni , Langlois Sylvia , MacDonald Laura , Vanier Marie-Claude , Puvirajah Anton
Published: September 2023

Background: In health and social care (HASC) professional education, interprofessional competencies are optimally developed by engaging in interprofessional education (IPE) activities that are delivered sustainably along a continuum. Ultimately, active engagement in IPE is meant to prepare future practitioners for interprofessional collaborative practice (IPCP), which leads to improved patient/client and community-oriented outcomes.
Methods and Findings: This qualitative case study explores how four Canadian post-secondary institutions deliver IPE within their HASC professional education programmatic structures. Data were collected from institutional websites, publicly available IPE relevant records and documents, and interviews with coordinators and faculty/facilitators of IPE curriculum. Data were inductively analyzed to generate relevant themes, followed by a deductive analysis guided by the five accreditation standards domains identified in the Accreditation of Interprofessional Health Education (AIPHE) projects. Analyses of the data resulted in five attributes: 1) central administrative unit, 2) longitudinal and integrative program, 3) theoretically informed curriculum design, 4) student-centred pedagogy, and 5) patient/client-oriented approach.
Conclusions: Using these attributes and guided by AIPHE’s accreditation standards domains, an organizational-curricular model for sustainable IPE is proposed, through which we assert that IPE reinforced through these organizational and curricular supports reflects successful programming, leading to patient/client-oriented outcomes.
Hydrological Modelling to Inform Forest Management: Moving Beyond Equivalent Clearcut Area
Authors: Chernos Matthew , Green Kim , MacDonald Ryan
Published: September 2023

Forest disturbance can alter the hydrologic conditions of a watershed, including the frequency, magnitude, and timing of peak and low flows. Equivalent Clearcut Area (ECA) has been routinely used in watershed assessments to estimate hydrologic alteration due to forest disturbance. ECA analyses typically rely on broad regional assumptions, qualitative observations, and/or expert judgement, making it difficult to provide accurate quantitative estimates of hydrologic change. Process-based hydrological models offer an improved approach since they replicate watershed processes, can simulate land cover and climate change scenarios, and provide quantitative estimates of hydrologic change, including at ungauged points of interest. A workflow using a regionally calibrated hydrological model to investigate forest disturbance and future climate change scenarios is demonstrated. Results are contrasted with ECA-based outputs and emphasize that in addition to the amount of forest disturbance, watershed physical characteristics and the location of disturbance within a watershed influence the hydrologic response. This approach provides forest managers with quantitative outputs that support risk-based forest management decisions and presents a substantial improvement over ECA-based methods.
Keywords: hydrological modelling, ECA-based analysis, watershed assessment, forest disturbance, cumulative effects, risk-based forest management
Del movimiento campesino al asociacionismo rural en el centro de Veracruz
Authors: Olguín Pérez Alfredo Martín , Sámano Rentería Miguel Ángel
Published: September 2023

El objetivo de la investigación fue analizar los factores históricos que incidieron en el origen de la acción colec­tiva de los pequeños cafeticultores, y estudiar el proceso que siguieron para forjar su identidad campesina por medio de la agroecología constituirse en la asociación civil Vinculación y Desarrollo Agroecológico en Café (VIDA) y consolidar su trabajo colectivo. La investigación es tanto teórica como práctica, se abordó mediante la revisión documental y trabajo de campo, lográndose aplicar cincuenta y dos entrevistas semiestructuradas y ocho testimonios de los actores sociales. El surgimiento de VIDA fue inducido por la Unión General Obrero Campesina y Popular (UGOCP) en Ixhuatlán del Café; la unión a líderes sociales de Cosautlán de Carvajal; y la Universidad Autónoma Chapingo, quienes trabajaron en conjunto para caracterizar los territorios cafeta­leros y los saberes tradicionales agrícolas, y sistematizar el manejo agroecológico del cafetal. El resultado fue la obtención de un café diferenciado para el comercio alternativo internacional y nacional. La movilización de los cafeticultores mediante su acción colectiva permitió vincularse a otros actores institucionales nacionales e internacionales. Los cuales les brindaron eficiencia organizacional y económica, y fortalecieron su postura política en defensa de la vida campesina agroecológica.
Economía rural familiar y el Proyecto Estratégico de Seguridad Alimentaria como generador de bienestar en Acambay, México
Authors: Magdaleno Hernández Adalberto , Quispe Limaylla Anibal Griceldo , Guajardo-Hernández Lenin Gerardo , Hernández-Juárez Martín , Omaña-Silvestre José Miguel , Caamal-Cauich Ignacio , Cruz-Cruz Nancy Vianey , Magdaleno-Hernández Edgar
Published: September 2023

Los análisis al PESA son abundantes, sin embargo, son escasos los estudios considerando las aportaciones que tiene en la economía rural familiar y las opiniones de los beneficiarios al respecto. El objetivo fue determinar los ingresos económicos anuales de las familias y analizar la contribución de los proyectos PESA al ingreso, para identificar si ésta aportación influyó favorablemente en el bienestar y particularmente en la alimentación de las familias. El estudio se efectuó en dos comunidades de Acambay, Estado de México. En agosto 2018 se realizó un censo a 39 beneficiarios y se entrevistaron 20 familias como testigo, se estimaron los ingresos econó­micos anuales y la aportación que en ellos tuvieron los proyectos PESA, se realizó un ANOVA de comparación de medias de Tukey, para determinar si existe diferencia estadística entre los ingresos económicos de ambas poblaciones. Los resultados mostraron que los ingresos anuales oscilan entre $69,000 y $73,300, de los que 77 y 80% correspondieron a pagos que obtuvieron por su mano de obra; la agricultura y ganadería sumadas contribuyeron entre 7 y 14% y las transferencias gubernamentales representaron 7%. Los proyectos PESA, aportaron, en promedio, 2% de los ingresos económicos. Se concluye que el PESA tuvo una insignificante aportación en el bienestar de las familias rurales y los participantes, reconocen el marginal efecto que tienen los proyectos sobre sus ingresos y la producción de alimentos, pero están satisfechos con lo recibido del programa.
Painted Pottery Decorative Patterns in the North-Eastern Anatolian Plateau during the Late Iron Age (8th–7th century BC to 330 BC)
Authors: Korbi Anete
Published: September 2023

The article offers a brief overview of the painted pottery decorative patterns on the north-eastern Anatolian plateau during the Late Iron Age. In this study, the author has examined painted pottery sherds of nine archaeological sites: Boğazköy, Alaca Höyük, Alișar Höyük, Ҫadir Höyük, Kerkenes Dağ, Ușaklı Höyük, Mașat Höyük, Kușaklı-Sarissa, Kaman-Kalehöyük. The total amount of painted pottery sherds examined is 344. Based on the evidence of the decorative painted patterns on the ceramic vessels dated to the Late Iron Age, the author has investigated the frequency and distribution of decorative types among the archaeological sites.
Pilsēta un vienradzis
Authors: Mintaurs Mārtiņš
Published: September 2023

Recenzija par grāmatu: Kuldīga un Kurzemes–Zemgales hercogiste Eiropā un pasaulē. Kuldīga 2022. 328 lpp.ISBN 978-9934-8991-3-3
Armed Forces of Georgian Democratic Republic in 1918–1921
Authors: Anchabadze George
Published: September 2023

The article is dedicated to the armed forces of the Georgian Democratic Republic (1918–1921). It shows the history of their creation and development, the composition and structure of the troops, as well as provides a brief insight into the combat path. It also shows the contradictions that existed between the socialist leadership of the country and a significant part of the officer corps, caused by ideological differences. The result of these contradictions were two forms of the armed organization of Georgia – the regular army and the People’s Guard, which caused discord in the armed forces. This circumstance, among other reasons, contributed to the military defeat of Georgia in the clash with Soviet Russia (1921).
Latvijas kultūras un mākslas sovetizācija pirmajā padomju okupācijas gadā: 1940. gada jūnijs – 1941. gada jūnijs
Authors: Stranga Aivars
Published: September 2023

Kultūras un mākslas attiecības ar jauno varu – padomju režīmu – ir nopietni pētītas Latvijas vēstures literatūrā. Ilgoņa Bērsona darbi par literatūras likteņiem, Arnolda Klotiņa – par mūziku okupācijā un Ilzes Konstantes pētījumi par tēlotāju mākslu ir ievērojami pēdējo gadu sasniegumi. Šajā esejas formas rakstā, papildinot vienu otru faktisko materiālu, veltīta uzmanība kolaborācijai un pat kolaboracionismam. Bez šo parādību plašas izplatības kultūras un mākslas sovetizācijas procesi nebūtu iespējami.
Vēstures mīti par “Senlatvijas” vardarbīgu pakļaušanu krusta karu laikmetā: mītu pārnese uz 20. gadsimta vēstures procesiem
Authors: Šumilo Marija
Published: September 2023

Gan nacionālisms, gan marksisms-ļeņinisms 20. gadsimtā Latvijas vēsturi traktēja kā spirālveida procesu. Tā saucamā “Senlatvija” tika uzlūkota kā zelta laikmets, kuram sekoja vēsturiskā netaisnība – krusta kari. Rakstā, balstoties uz 20. gadsimta akadēmiskajiem, periodiskajiem un mācību izdevumiem, aplūkoti mitoloģizētie priekšstati par Latvijas teritorijā dzīvojušo baltu un somugru etnokulturālo grupu vienotību aizvēstures beigu posmā un apzinātu pretošanos krustnešiem, lai krusta karu laikmetā saglabātu valstiskumu, kultūru un reliģiju. Raksta mērķis ir analizēt šo priekšstatu pārnesi uz 20. gadsimta Latvijas vēstures procesiem.
Reflection of the Mongol imperial ideas in medieval Russian sources
Authors:   Saint-Petersburg State University, Drobyshev Yuliy I.
Published: September 2023

The purpose of the research: This research builds upon the author’s previous work focused on exploring the reflection of Mongolian imperial ideology in sources from various countries that were influenced to varying degrees by the Mongolian expansion during the 13th and 14th centuries. The objective is to search for and systematically categorize the manifestations of Mongol ”world-organizing” ideas within Russian sources. Research materials: The primary sources for this study were the oldest Russian chronicles, including the Laurentian, First Novgorod, and Hypatian chroniclew, along with several others. Valuable information was also extracted from collections of yarlyqs (edicts) from Mongol khans to Russian metropolitans, hagiographic literature, and religious records. Comparative materials from Eastern and European sources were utilized to elucidate the identified elements of Mongolian ideology. The works of both Russian and foreign historians, specializing in Russian and Mongolian history, were extensively referenced. The results of the research and scientific novelty: This research reaffirms conclusions made by other experts regarding the limited interest among Russian scribes in the material and spiritual culture of the Mongols. Ideological aspects of Mongolian power are scarcely documented in Russian sources, although in some instances, they can be reasonably reconstructed. The foundations of Mongolian ”universalism,” such as the concept of Eternal Heaven, the deification of Genghis Khan, and the Great Yasa attributed to him, have left traces in chronicles and other historical sources. Russian sources also provide supplementary information highlighting Mongolian “imperialism,” including the Mongol Empire’s system of titles, interactions between the Ulus of Jochi and Karakorum, and the steppe rituals that princes were compelled to perform within the Horde. Overall, Russian materials do not support the notion that the Mongols aimed to conquer ”the whole world.”
Heritage of the Golden Horde Tatars: scientific events
Authors:   Kazan National Research Technical University named after A.N. Tupolev – KAI, Giniyatullina Rozalina R.
Published: September 2023

The Marjani Institute of History of the Tatarstan Academy of Sciences is a leading humanities research center in Tatarstan. It is one of the recognized and authoritative regional centers in Russia and an important link in international academic cooperation in the field of studying the history of the Tatars, Tatarstan, Eurasian history, and Turkic-Tatar civilization. Researchers from the Usmanov Center for Research on the Golden Horde and Tatar Khanates of the Marjani Institute of History of the Tatarstan Academy of Sciences, in collaboration with colleagues from other research centers in the Russian Federation and abroad, not only investigate the historical realities of the past, including the Golden Horde state and Tatar Khanates but also develop common approaches to its history, which is essential in modern conditions. As part of this work, roundtable discussions and presentations were organized in Bashkortostan and the Samara Region in May-June 2023. All of these scientific events provide a significant impetus for the study of the legacy of the Tatars of the Golden Horde at the regional and international levels. An important outcome is the establishment of cooperation between historians and local historians from the Volga and Ural regions. Joint discussions of scientific issues have allowed not only to outline the prospects for further research, but also to establish new productive traditions in the relationships between professionals and history enthusiasts.
Resistência da Helicobacter pylori aos antibióticos utilizados em diferentes esquemas terapêuticos: uma revisão integrativa
Authors: Santiago Silvana Barbosa , Rodrigues Jéssica Alves , Moraes Felipe Augusto de Sousa , Maximo Gabriel Ribeiro , Soares Giovana Alice Sampaio , Barbosa Mônica Santiago
Published: September 2023

Helicobacter pylori é uma bactéria gram-negativa que coloniza a mucosa gástrica de mais da metade da população mundial. A erradicação dessa bactéria é realizada com terapia tripla de primeira linha para reduzir o aparecimento de doenças gástricas relacionadas à infecção. H. pylori foi considerada pela Organização Mundial da Saúde uma das principais bactérias que necessitam de novas estratégias para o desenvolvimento de fármacos. O objetivo desse estudo foi descrever o padrão de resistência da H. pylori frente aos antibióticos utilizados em diferentes esquemas terapêuticos. Trata-se de uma revisão integrativa, cujo levantamento dos artigos foi efetuado nas bases de dados PubMed, LILACS, Science Direct e SciELO. Os critérios de inclusão foram estudos publicados em português e inglês, indexados nos últimos dez anos, com acesso livre na íntegra e que abordassem a temática. Os resultados demonstraram médias nas taxas de resistência ao metronidazol de 47,6%, levofloxacina de 24,7% e claritromicina de 24,6%. Para tetraciclina e amoxicilina as médias foram 1,5% e 0,9% respectivamente. Esses resultados demonstram padrões variáveis de resistência e reforça a necessidade do desenvolvimento de novos fármacos. Conclui-se que o uso abusivo de antibióticos tem levado ao aumento da resistência da H. pylori aos antibióticos usados na erradicação.
Pneumonia eosinofílica e provável Síndrome de Churg-Strauss: um relato de caso
Authors: Zambiasi Alícia Regina , Dalbosco Ana Katharina , Suzin Giordana Vitória Bertozzo , Zambiasi Lucas
Published: September 2023

As doenças pulmonares eosinofílicas compõe um grupo heterogêneo de patologias que possuem uma característica em comum: elevado número de eosinófilos nas vias aéreas e no parênquima pulmonar. Uma das formas de eosinofilia pulmonar é a Síndrome de Churg-Strauss (SCS), que é uma doença multissistêmica a qual possui evolução subaguda com três fases clínicas sequenciais: a prodrômica, a eosinofílica e a vasculítica. A hipótese diagnóstica pode ser considerada quando um padrão de opacidades em vidro fosco e consolidações são vistos em paciente com história de asma com eosinofilia.
Evaluation of terminal cleaning using ATP methodology: comparison of bleach and quaternary ammonium compound plus biguanide
Authors: Silva Paola Cristini Gama , Deutschendorf Caroline , Lisboa Thiago Costa , Silva Cristofer Farias da
Published: September 2023

Distinct protocols can be used to clean the hospital environment. This study used the ATP tool to evaluate cleaning protocols composed of either a quaternary ammonium compound plus biguanide (QACB) or bleach only. No statistical difference was found (p = 0.450) between QACB and bleach protocols, both being effective in hospital ward cleaning. So, it is possible to conclude that the use of QACB or bleach protocols ensures appropriate cleaning in health care, promoting a safe environment for patient use.
Compromiso gastrointestinal y hepático en Síndrome de Sjögren primario: reporte de caso y revisión de la literatura
Authors: Parra Izquierdo Viviana , Frías Ordoñez Juan Sebastián , Ovalle Hernández Alan Felipe , Costa Barney Valeria Atenea , Flórez Sarmiento Cristian Fabián , Hani de Ardila Albis Cecilia
Published: September 2023

El síndrome de Sjögren es una enfermedad autoinmune sistémica que se caracteriza por sequedad ocular y bucal por afección de glándulas exocrinas, sin embargo, puede manifestarse con síntomas gastrointestinales que abarcan un espectro amplio que van desde dismotilidad esofágica  e intestinal, acalasia, hipoclorhidria, gastritis crónica atrófica, hasta enzimodeficiencia pancreática, disfunción biliar y cirrosis hepática, presentando variación en sus manifestaciones clínicas, y asociándose abordajes erróneos en muchas ocasiones. En este artículo se hace una revisión acerca de las manifestaciones gastrointestinales de síndrome de Sjögren, y se presenta el caso de una mujer en la octava década de la vida con síndrome de Sjögren, cursando de modo asintomático a nivel hepatobiliar, documentación de alteración en pruebas de perfil hepático, y diagnóstico ulterior de colangitis esclerosante primaria, recibiendo manejo inicial con ácido ursodesoxicólico y colangiopancreatografía retrograda con dilataciones endoscópicas. Esta asociación es infrecuente y justifica consideración especial.
Drenaje de pseudoquistes pancreáticos usando stent metálico luminal de aposición (LAMS): experiencia en dos centros de referencia en Colombia
Authors: Flórez Sarmiento Cristian , Parra Izquierdo Viviana , Frías Ordoñez Juan Sebastián , Castillo Jesús David , Rodríguez Stefani
Published: September 2023

Introducción: el drenaje guiado por ultrasonido endoscópico (USE) y el uso de stent metálico luminal de aposición (LAMS) son de elección en el manejo de los pseudoquistes pancreáticos sintomáticos.
Objetivo: evaluar la efectividad y seguridad del LAMS para el drenaje por USE de pseudoquistes pancreáticos sintomáticos en dos centros de referencia en Colombia.
Materiales y métodos: estudio de cohorte prospectivo multicéntrico entre junio de 2019 y diciembre de 2021, se incluyeron a 13 pacientes con diagnóstico de pseudoquistes pancreáticos sintomáticos sometidos a drenaje por USE con LAMS. Se evaluaron como desenlaces el éxito técnico, el éxito clínico y la extracción exitosa del stent. Y los desenlaces de seguridad incluyeron eventos adversos relacionados con el stent y los eventos adversos generales. Se realizó seguimiento a 8 semanas, en las que se recopilaron datos relacionados con el retiro del stent.
Resultados: la edad promedio fue 53,4 años, 8/13 fueron hombres. El tamaño medio del pseudoquiste fue de 9,56 ± 2,3 cm. El éxito técnico fue del 100% y el éxito clínico fue 92,3%. Los stents fueron retirados en promedio a las 8 ± 2 semanas. El tiempo medio del procedimiento desde la punción hasta el despliegue del stent fue 3,2 ± 2,4 minutos. En el control imagenológico hubo un adecuado drenaje de las colecciones en todos los casos. Hubo baja frecuencia de complicaciones, se documentó sangrado en 1 caso con requerimiento quirúrgico.
Conclusiones: el uso de LAMS es seguro y efectivo en el manejo de pseudoquistes pancreáticos sintomáticos, disminuye la estancia hospitalaria y sobrecostos. La sintomatología clínica prima en la decisión de intervención.
Diarrea crónica por espiroquetosis intestinal en un paciente VIH positivo: reporte de un caso y revisión de la literatura
Authors: Valencia Tapiero Víctor Daniel , Figueroa Avendaño Carlos Edgar
Published: September 2023

La espiroquetosis intestinal se define como la colonización del epitelio colorrectal por espiroquetas anaerobias del género Brachyspira. Se identifica con mayor frecuencia en países en vías de desarrollo o cuando las condiciones de salubridad son subóptimas. Puede afectar a cualquier persona, aunque es más común en hombres homosexuales particularmente infectados por virus de la inmunodeficiencia humana (VIH). Su síntoma más frecuente es la diarrea crónica acuosa. La colonoscopia puede ser normal. Se presenta el caso clínico de un paciente masculino joven con diarrea crónica de varios años de evolución que se resuelve al brindar tratamiento específico. Además, se realiza, una revisión de la literatura sobre esta enfermedad.
Developing a Prognostic Signature with Cancer-Associated Fibroblasts for Predicting the Prognosis and Immune Landscape of Prostate Cancer
Authors: Kong Xubo , Liu Qin , Yang Jin , Wang Ruyi , He Jiangshu , Zhang hanchao
Published: September 2023

Background: Prostate cancer (PCa) is the common malignant disease in
older men. Cancer-associated fibroblasts (CAFs) are a vital components
of the TME and the major subpopulation of cells that promote tumor
heterogeneity. However, there are still few studies on the correlation
between PCa and CAFs. Thus, we predicted the prognosis of PCa by
investigating CAFs characteristics in PCa and constructing a prognostic
model with CAFs-related features. Methods: Firstly, we obtained the
scRNA-seq and clinical data on PCa from the GEO and TCGA databases. We
adopted a survival analysis to evaluate the impact of three distinct
CAFs subtypes on the prognosis of PCa patients. Besides, we identified
different CAFs by integrated univariate Cox regression analysis, LASSO
analysis, and multivariate Cox regression analysis. Based on the CAFRGs,
we built a prognostic model to exhibit PCa prognostic relevance and
validated the prognostic signature. We also screened the drugs for PCa.
Furthermore, we explored the correlation between malignant features and
PCa. Results: We revealed that apCAFs and myCAFs were significantly
correlated with PCa patient prognosis. 5 prognostic CAFRGs (SYNM, NR4A1,
MSMB, HOPX, and GJC1) were screened by integrated analysis. We found
that the low-risk group patients had significantly higher survival
rates. And validation analyses targeting the prognostic model indicated
that the high-risk group patients were more to exhibit higher BCR across
external validation sets. The ssGSEA algorithm indicted that the
majority of the immune cells had increased levels of infiltration and
higher immune function scores in the high-risk group. Furthermore, the
z-score algorithm results showed that CAFRG was closely connected
angiogenesis, EMT, and cell cycle scores. Conclusion: In conclusion, we
build a prognostic model with CAFs prognostic characteristics for PCa to
offer further prediction of PCa prognosis and immunotherapy response,
which ultimately guides the clinical management of PCa.
Analysis of Waist and Wrist Positioning Wearable Machine Learning Models to Detect Falls
Authors: Nuñez Teddy Ordoñez , Ramirez Alejandro , Marón Liliam Becherán
Published: September 2023

Falls are a widespread issue affecting people worldwide, regardless of
their social status. Falls lead to physical, psychological, and economic
consequences. Experts are developing solutions for this problem, given
the high frequency of falls among the elderly. This study presents
various ML models, which can predict human falls using signals of a
wearable sensor located on the wrist or the waist. By extracting the
mean, standard deviation, and range, we were able to train and evaluate
various machine learning models considering accelerometers and
gyroscopes as sensors. The combination of these characteristics and
sensors resulted in the RF waist model achieving the most favorable
metrics, achieving an accuracy rate of 97.22%.
The “power of weakness”? The Western Balkans and Europe’s global neighbourhood
Authors: Balazs Bence
Published: September 2023

Putin?s war in Ukraine might result in a shift from the worn-out refrain of
?Europeanization? towards a more realist approach to EU enlargement and its
geostrategic stakes. Russia has turned into a significant threat due to its
weakness rather than its power. The author considers the ?power of weakness?
a crucial concept in the ongoing aggression and its geostrategic
consequences. Paradoxically, weakness might be an actual source of power in
these uncertain times of global transformation. is that an opportunity for
the Western Balkans (WB)? Analyzing the troublesome Western Balkans? EU
integration based on their economic, demographic, and other (limited)
features while relying on the decolonization approach, the author finds that
their integration constitutes an emergency precisely due to their weak
points. Russia and China seek for weakening states across the globe, minor
players where anti-Western feelings are easy to instrumentalize. The WB
candidates deserve to be better integrated into the list of European
priorities. A lack of EU strategy in the WB might indicate the absence of
sound perspectives for the Union?s broader international role. The paper
explores Bertrand Badie?s decolonization approach, applying it to the
Western Balkans, Hungary?s practice regarding the ?power of the weak?, and
Turkey, aiming to illustrate that weakness should not be perceived solely as
the opposite of power, but as a suspicious international element since the
Cold War onwards.
Pesticidal Effects of Hyoscyamus aureus L
Authors: Atalla Akram
Published: September 2023

Serial dilutions of Hyoscyamus aureus L extract were tested on three kinds of organisms; they are cockroach, red spiders and ants. The result showed that the minimum killing concentration was 62.5 mg/ml where at this concentration; the extract killed all the organisms. The experiments showed that the tropane alkoides contents in this plant have significant pesticidal effects.
Effects of Bee Bread Supplementation on Anaerobic Components in Male Athletes
Authors: Wong Chee Ping Fadzel
Published: September 2023

Nutritional strategies are the common types of ergogenic aids used by athletes to enhance their sports performance. Scientific data on the ergogenic effects of bee products consumed at pre exercise on anaerobic sports performance is scanty. This study investigated the effects of 8-week bee bread supplementation at pre exercise on anaerobic components in male athletes. Twelve male athletes (age: 24.0 ± 1.8 years old; BMI: 22.3 ± 1.3 kg.m-2; VO2max: 52.0 ± 2.8 mL.kg-1.min-1) were recruited in this study. Participants consumed either bee bread at a dosage of 20 g.d-1 or placebo for 8 weeks prior to the experimental trial. Participants’ anaerobic components such as mean power, peak power, anaerobic capacity and anaerobic power was measured before and after 8 weeks of experimental period. Statistical analyses were performed using ANOVA with repeated measures. There were no significant different in mean power, peak power, anaerobic capacity and anaerobic power between placebo and bee bread trial at pre and post supplementation test. Supplementation of bee bread for 8 weeks at a dosage of 20 g daily didn’t enhance anaerobic components in male athletes.
Propuesta de instrumento de evaluación de las emociones básicas de los estudiantes dentro de un programa de tutoría universitaria
Authors: Arámburo-Lizárraga Jesús
Published: September 2023

En este artículo se aborda el tema de la alfabetización emocional aplicada a un programa de tutoría en el momento de ingreso de estudiantes universitarios. Para ello, se propuso un instrumento que considera la importancia de las emociones durante las sesiones realizadas dentro de la tutoría. En tal sentido, se considera que el tutor es capaz de tener una inteligencia emocional para ser objetivo ante los problemas de sus estudiantes. Durante el desarrollo, se establecieron los elementos necesarios para su implementación y se consideró una tabla de emociones básicas (felicidad, tristeza, ira, sorpresa, miedo, disgusto y vergüenza) para su análisis. El instrumento de evaluación propuesto generó por cada estudiante una tabla de sentimientos predominantes, los cuales el tutor debe conocer para determinar la dimensión de esas emociones. En síntesis, se presenta una ejecución del instrumento en una hoja de cálculo, lo cual demuestra su utilidad y cómo se pueden caracterizar los sentimientos predominantes de los alumnos al ingresar a la universidad.
Editorial da edição especial em português.
Authors: Nóbriga Jorge Cássio Costa , Dantas Sergio Carrazedo
Published: September 2023

Nesta edição especial gostaríamos que essa história fosse contada de forma mais explícita. Evidentemente, não seria possível fazer uma edição com todos os autores que já publicaram na revista contando suas histórias com o GeoGebra. Dessa forma, convidamos autores que, de alguma forma, têm representatividade e reconhecimentos dentro da comunidade GeoGebra no Brasil pelos trabalhos que vem desenvolvendo com o software.
Um pouco da minha história com o GeoGebra e alguns exemplos de atividades
Authors: Nóbriga Jorge Cássio Costa
Published: September 2023

Este texto apresenta um pouco da história acadêmica de um professor/pesquisador que trabalha com softwares educativos de Matemática há mais de 20 anos. Além disso, expõe alguns exemplos de atividades matemáticas produzidas no GeoGebra e que podem ser usadas em diversos níveis de ensino. Basicamente, o texto está dividido em seções que mostram alguns fatos marcantes durante a formação acadêmica e como algumas teorias foram sendo apropriadas e usadas nas pesquisas e produções das atividades. Por fim, são apresentadas as considerações finais com algumas sugestões de formas de utilização dos materiais.
Tumor Ki-67, ER and PR, and antibodies against estradiol and progesterone in breast cancer patients
Authors: Glushkov A. N. , Polenok E. G. , Mun S. A. , Gordeeva L. A. , Kostyanko M. V. , Antonov A. V. , Bayramov P. V. , Verzhbitskaya N. E. , Kolpinskiy G. I.
Published: September 2023

Aim. To investigate the associations of cell proliferation marker Ki-67 in estrogen receptor (ER) and progesterone receptor (PR) positive (ER+/ PR+) and negative (ER-/PR-) tumors with the ratio of antibodies against estradiol and progesterone (IgA1-E2/IgA1-Pg) in the serum of breast cancer (BC) patients.

Materials and Methods. Antibodies against steroid hormones were analyzed by ELISA in the serum of 432 healthy women and 1212 patients with BC (573 patients with I stage and 639 patients with II–IV stages). Expression of Ki-67, ER and PR in tumors was determined by immunohistochemical staining. Serum estradiol and progesterone were measured by enzyme-linked immunosorbent assay.

Results. In total, low IgA1-E2/IgA1-Pg (≤ 1) and high IgA1-E2/IgA1-Pg (> 1) ratio were revealed in 49.3% and 50.7% of healthy women; in 25.7% and 74.3% of stage I BC patients with tumor Ki-67 < 14 (р < 0.001; OR = 0.4 and OR = 2.8, respectively), and in 17.1% and 82.9% of stage I BC patients with tumor Ki-67 > 30 (р < 0.001; OR = 0.2 and OR = 4.7, respectively). The differences between patients with low and high tumor Ki-67 levels in relation to low and high IgA1-E2/IgA1-Pg ratio were statistically significant (p = 0.03). In stage I BC patients with ER+/PR+ and tumors with Ki-67 < 14, low and high IgA1-E2/IgA1-Pg ratio were found in 25.0% and 75.0% cases (р < 0.001; OR = 0.3 and OR = 2.9, respectively). In stage I BC patients with ER+/PR+ and tumors with Ki-67 > 30, low and high IgA1-E2/IgA1-Pg ratio were found in 12.9% and 87.1% cases (р < 0.001; OR = 0.2 and OR = 6.6, respectively). In patients with ER+/PR+ tumors, the differences between patients with low and high tumor Ki-67 levels in relation to low and high IgA1-E2/IgA1-Pg ratio were also statistically significant (p = 0.009). In patients with ER-/PR- tumors, the differences between patients with low and high Ki-67 levels in relation to low and high IgA1-E2/IgA1-Pg ratio were not revealed. The proportion of breast cancer patients with tumor Ki-67 > 30 increased from I to II–IV BC stages regardless of IgA1-E2/IgA1-Pg ratio.

Conclusion. IgA1-E2/IgA1-Pg ratio may serve as a predictor of tumor proliferative activity in stage I BC patients with ER+/PR+ tumors.
Hypoxia-inducible factors: details create a picture. Part I. HIF-1
Authors: Ignatenko G. A. , Bondarenko N. N. , Tumanova S. V. , Ignatenko T. S. , Kaluga A. A. , Valigun Ya. S.
Published: September 2023

The review presents a comparative analysis of scientific data on the structural and functional characteristics of subunits (HIF-1α and HIF-1β) of hypoxia-inducible transcription factor-1 (HIF-1). Differences between the main regulatory HIF-1α subunit and the constitutively expressed HIF-1β subunit, sensitivity to endo- and exogenous regulators of their stability, and intracellular content depending on the cell's oxygen supply state (normoxia and hypoxia conditions) are described. In normoxia, the intracellular content of HIF-1α is determined by oxygen-dependent and oxygen-independent mechanisms. Oxygen-dependent enzymatic degradation of HIF-1α occurs by PHD-dependent hydroxylation, VHL-dependent ubiquitination, and FIH-1-dependent hydroxylation. Oxygen-independent pathways of HIF-1α pool regulation include: 1) HIF-1α gene transcription (Notch and/or NF-KB-dependent, STAT3 and Sp1 cytokine-dependent), 2) mRNA translation (cap-dependent or IRES-dependent, as well as cytokine-dependent activation of the PI-3K/AKT pathway activation under the effect of growth factors and vasoactive hormones), 3) protein-protein interactions, 4) various mechanisms of post-translational modification. Changes in Krebs cycle enzyme activity and active oxygen forms confer HIF-1α stability through PHD activity inhibition and reduction of ubiquitin-proteasome degradation. PHD-independent post-translational stabilizers of HIF-1α are: cytosolic reductase NQO1, sirtuin-2, prostaglandin E2, activated protein kinase C1 receptor competing with heat shock protein 90, human Hdm2 (a natural inhibitor of p53), glycogen synthase kinase 3β, and negative modifiers are enzymes - methyltransferase SET7/9, lysine-specific demethylase-1, sex-like kinase 3, β-arrestin-2, casein kinase-1. Under hypoxic conditions, non-hydroxylated HIF-1α subunits migrate to the nucleus where they heterodimerize with HIF-1β, HIF-1α/β heterodimers bind the main 5'-(A/G)CGTG-3' consensus sequence within the hypoxia-reaction element (HRE) of the target genes, and recruit co-activators (p300, histone modifying enzymes, histone readers, chromatin remodeling proteins, and mediator proteins for target genes transcription enhancement with the aid of RNA polymerase II), resulting in the formation of HIF-1, acting as a transcription factor for the target genes providing metabolic reprogramming from oxidative phosphorylation to anaerobic glycolysis (genes encoding glucose transporters (GLUT1 and GLUT3), genes for glycolytic enzymes hexokinase 1 and 2 (HK1 and HK2), phosphoglycerate kinase 1), as well as genes for erythropoietin, vascular endothelial growth factor and its receptors FLT1 and FLK1, endothelin 1 and angiopoietin 1, resulting in adaptation to hypoxia.
Sosiaalityöntekijöiden työlleen asettamat tavoitteet gerontologisessa sosiaalityössä
Authors: Soukiala Tiina
Published: September 2023

Tarkastelen tutkimuksessani tavoitteita, joita sosiaalityöntekijät asettavat työlleen iäkkäiden kanssa työskennellessään. Tavoitteenani on jäsentää gerontologisen sosiaalityön tavoitteita ja nostaa esiin näkökulmia sen erityispiirteistä. Sosiaalityöntekijän erilaisten tavoitteiden tunnistaminen, sanallistaminen ja tietoinen asettaminen edistävät moniammatillista yhteistyötä ja gerontologisen sosiaalityön työkäytäntöjen kehittymistä sekä vahvistavat auttamistoiminnan vaikuttavuutta. Tutkimuksen aineisto koostuu iäkkäiden kanssa työskentelevien sosiaalityöntekijöiden ryhmäkeskusteluista, joita analysoin abduktiivisesti filosofisten toiminnan teoreettisten käsitevälineiden avulla. Tulosten mukaan sosiaalityöntekijöiden toiminnan tavoitteena oli turvata asiakkaan välttämättömät perustarpeet, vahvistaa iäkkään, tämän läheisen tai toisen ammattilaisen toiminnan edellytyksiä sekä saada aikaan auttamisen mahdollistavat olosuhteet. Sosiaalityöntekijöiden tavoitteenasettelussa korostuivat välttämättömien perustarpeiden turvaaminen ja iäkkään suojelu. Työssä painottui yksilökohtainen sosiaalityö, ja työtä tehtiin pääasiassa sellaisten iäkkäiden kanssa, joiden ongelmat olivat jo hyvin vakavia. Sosiaalityöntekijöiden tavoitteet kohdistuivatkin pitkälti ongelmien lievittämiseen ja vähemmän hyvinvoinnin vahvistamiseen sinänsä. Gerontologisen sosiaalityön tavoitteeksi tulisi ymmärtää iäkkään hyvinvoinnin kokonaisvaltainen edistäminen ja tältä pohjalta tarkastella ja tarvittaessa uudelleen määritellä gerontologisen sosiaalityön sisältö ja paikka palvelujärjestelmässä.
Social workers’ goals in gerontological social work
This study examines the kinds of goals social workers set when working to improve the wellbeing of older adults. The data consist of seven focus groups of gerontological social workers. The material was analysed using concepts from philosophical action theory. The analysis showed that gerontological social workers aimed to secure their clients’ basic needs, focused on strengthening action capabilities for their clients, clients’ relatives or other professionals, and attempted to create conditions that allowed them to help their clients. The social workers prioritised securing their clients’ essential basic needs and safeguarding them. At the same time, in the practice of gerontological social work, more attention would be needed for relationship-based practice and structural social work. A better understanding of the goals of social workers’ actions helps to systematise work practices in gerontological social work and increases the effectiveness of helping actions.
Osastonhoitajien kokemukset saamastaan tiedosta ja tuesta sekä toiminnan muutoksen johtamisesta Terveyskylän digihoitopolun käyttöönotossa: laadullinen tutkimus
Authors: Mikkonen Hanna , Wahlberg Janika , Paalimäki-Paakki Karoliina , Jauhiainen Jukka , Liljamo Pia
Published: September 2023

Digitalisaatio mahdollistaa terveydenhuollon uudistumisen. Digitaalisten palveluiden käyttöönotossa tarvitaan muutoksia organisaation sisäisiin rakenteisiin ja työprosesseihin. Johtajilla on merkittävä rooli digitaalisen palveluiden käyttöönoton tukemisessa ja uusien toimintamallien juurruttamisessa osaksi arkea. Digitalisaatio muuttaa myös johtajuutta ja johtajien käyttäytymistä. Johtajat tarvitsevat digitalisaation hyödyntämiseen liittyvää osaamista. Lisäksi he tarvitsevat tukea ja koulutusta sähköisten palveluiden käyttöönottoon.
Tämän laadullisen tutkimuksen tarkoituksena oli kuvailla osastonhoitajien kokemuksia saamastaan tiedosta ja tuesta toiminnan muutoksen johtamisessa sekä toiminnan muutoksen johtamiseen vaikuttaneista tekijöistä Terveyskylän digihoitopolun käyttöönoton yhteydessä. Digihoitopolku on verkkopalvelu, jolla voidaan korvata tai täydentää perinteisiä terveydenhuollon käyntejä. Tutkimusaineisto kerättiin teemahaastattelulla yhden yliopistosairaalan osastonhoitajilta (n=6). Aineisto analysoitiin sisällönanalyysillä.
Osastonhoitajat kokivat saaneensa verkostoiltaan tukea, tietoa digihoitopolun käyttöönotosta ja toiminnan muutoksesta sekä konkreettista tukea kehittämiseen. Toisaalta saadussa tiedossa ja tuessa koettiin olleen puutteita ja haasteita kehittämisprosessin aikana. Käyttöönottoon liittyvää toiminnan muutoksen johtamista edistivät resursoinnin ja rahoituksen toteutuminen, positiivinen asenne kehittämiseen ja osaamisen kartuttaminen, tavoitteellisuus kehittämisprosessissa, osallistaminen ja yhteiskehittäminen sekä verkostoilta saatu tuki ja sähköisten palveluiden aktiivinen käyttöönotto. Muutoksen johtamista haastoivat resursointi ja aikataulut, muutosvastarinta, toiminnan muutokset, puutteet tuessa ja digiosaamisessa sekä tietojärjestelmän tekniikka.
Osastonhoitajat saavat tietoa ja tukea toiminnan muutoksen johtamiseen, mutta tiedon tulee olla esimiehille suunnattua. Ylemmän johdon tukea tarvitaan etenkin tavoitteiden asetteluun ja digihoitopolun hyötyjen konkretisoimiseen. Digihoitopolun käyttöönotossa onnistuneeseen toiminnan muutokseen vaaditaan riittävät aika- ja henkilöresurssit.
Tutkimuksella saatua tietoa voidaan hyödyntää digihoitopolkujen sekä muiden sähköisten palveluiden kehittämisessä, käyttöönotoissa ja toiminnan muutoksen johtamisessa sosiaali- ja terveydenhuollossa sekä esimiehille tarkoitettujen koulutusten suunnittelussa.
Perbandingan Metode Prediksi Laju Galat dalam Pemodelan Klasifikasi Algoritma C4.5 untuk Data Tidak Seimbang
Authors: Yunistika Ilanda  , Dodi Vionanda  , Yenni Kurniawati  , Dina Fitria
Published: September 2023

Pemodelan klasifikasi dapat dibentuk menggunakan algoritma C4.5. Model yang dibentuk oleh algoritma C4.5 perlu dilihat akurasi prediksinya menggunakan metode prediksi laju galat. Metode prediksi laju galat yang membedakan data training dan data testing memiliki kinerja lebih baik. Tiga metode prediksi laju galat dengan pembagian data training dan testing yang sering digunakan yaitu Hold Out (HO), Leave One Out Cross Validation (LOOCV), dan K-Fold Cross Validation (K-Fold CV). Penelitian ini berfokus pada perbandingan metode prediksi laju galat HO,LOOCV, dan K-Fold CV pada algoritma C4.5 untuk kasus data tidak seimbang, sebab kasus ini sering dijumpai dalam kasus nyata klasifikasi. Data tidak seimbang menyebabkan peningkatan kesalahan klasifikasi algoritma C4.5 sebab hasil prediksi tidak merepresentasikan seluruh data dan memperburuk kinerja metode prediksi laju galat. Sementara itu, kasus data dengan korelasi berbeda dilakukan untuk mengetahui apakah beda korelasi mempengaruhi kinerja metode prediksi laju galat. Tujuan penelitian untuk mengetahui metode prediksi laju galat yang paling cocok diterapkan pada algoritma C4.5 kasus data tidak seimbang dan pengaruh beda korelasi. Hasil penelitian menunjukkan metode K-Fold CV adalah metode prediksi yang paling cocok diterapkan pada algoritma C4.5 kasus data tidakseimbang dibanding metode HO dan LOOCV. Selain itu, Korelasi tinggi dapat memperburuk kinerja metode prediksi laju galat.
Editörden
Authors: ÇAKMAK Tolga
Published: September 2023

Türk Kütüphaneciliği Dergisinin 37. Cildinin 3. Sayısı için hazırlanan editörden bölümüdür.
Karaoğlu, G. (Editör). (2022). Dijital okuryazarlık. Efe Akademik. ISBN: 978-625-8217-07-0
Authors: ÇAKMAK Nermin
Published: September 2023

Bu çalışmada, Gülhanım Karaoğlu’nun editörlüğünü yaptığı “Dijital Okuryazarlık” başlıklı kitabın incelenmesi amaçlanmaktadır. Her bölümü farklı yazarlar tarafından kaleme alınan kitap, geleneksel medya okuryazarlığı, dijital medya platformları, bilgi/enformasyon okuryazarlığı, dijital ekonomi, yeni medyada sahte haber, sağlıkta dijital medya okuryazarlığı, dijital reklam okuryazarlığı vb. gibi dijital okuryazarlık konusunu geniş bir yelpazede ele alan on sekiz bölümden oluşmaktadır. Kitapta dijital okuryazarlık konusu kuramsal ve uygulamalı çalışmalarla pek çok açıdan kapsamlı bir şekilde ele alınmıştır. Kitap konuya ilgi duyan herkesin yararlanabileceği bir nitelik taşımaktadır. Bununla birlikte Bilgi ve Belge Yönetimi alanındaki akademisyenler de kitaptan ilgili dersler kapsamında faydalanabilirler. Diğer taraftan bilgi uzmanları da bilgi merkezlerinde kullanıcı/bilgi okuryazarlığı gibi eğitimleri planlarken kitaptan yararlanabilirler.
The Effect of Superplasticizer (SP) on the Workability and Skid Resistance of Geopolymer Concrete (GPC) Containing High Calcium Precursor (HCP)
Authors: Mohd Apandi Nazirah
Published: September 2023

A superplasticizer (SP) is one of the admixtures that may be used to improve the workability of concrete. However, its effects on geopolymer concrete (GPC) have yet to be well known or published, especially regarding its skid resistance and workability performance. This research aims to study the impact of the superplasticizer on the skid resistance and workability of geopolymer concrete containing high calcium precursor (HCP) in different proportions of SP, which are 0, 0.5, 1.0, 1.5 and 2.0 % by the weight of the HCP. Seven mix designs were produced: 1 conventional concrete mix, 5 geopolymers concrete mix, and 1 bituminous cold-mix asphalt mix. Slump flow and skid resistance tests were performed in this study. A skid resistance test is achieved using a British Pendulum Tester (BPT) on a 220 mm x 220 mm x 50 mm rectangle. This study found that the effect of SP on skid resistance is insignificant. However, the skid resistance of all GPC mix designs is higher than CC and asphalt mix. The workable flow of geopolymer concrete containing HCP and 0 - 2 % SP was 118-123 mm. However, less than 2 % of SP is given an insignificant difference. The optimum mix design of GPC is mix design GPC with an added 2 % SP (M6) that gives a high workability compared to other GPC mix designs and good skid resistance of 95 BPN. This study also found that workability correlates with skid resistance. The higher the spreading width value, the smaller the skid resistance value. In other words, the higher the flowability value, the less rough the sample surface. Hypothetically, the higher the percentage of SP, the higher the workability and the lower the skid resistance.
Revival of Ferromagnetic-Metallic Phase and Emergence of Griffiths Phase via Ni and Cr Substitution in Charged-Ordered Pr0.75Na0.25MnO3 Manganite
Authors: Rajmi Rozilah
Published: September 2023

Polycrystalline samples of Pr0.75Na0.25Mn1-xAxO3 (A = Ni, Cr; x = 0, 0.03) were prepared using conventional solid-state method and their structural and magnetic properties were investigated. Monovalent-doped Pr0.75Na0.25MnO3 exhibits insulating behavior which is related to the strong localization of charge carriers due to the presence of charge ordering (CO). The substitution of different types of magnetic ions, A, which are Ni2+ and Cr3+, at a concentration of x = 0.03 at the Mn site in the CO Pr0.75Na0.25Mn1-xAxO3 manganite, has been found to dramatically modify its structural and magnetic properties. X-ray diffraction patterns showed that all samples were present in single phase and crystallized in orthorhombic structure with Pnma space group. The Rietveld refinement analysis showed that the unit cell volume increased due to Ni2+ substitution, while it decreased due to Cr3+ substitution, which may be attributed to the different ionic radii of both ions. The suppression of the CO state and the induction of the ferromagnetic-metallic state in the Ni-substituted and Cr-substituted samples are suggested to be due to the induction of double-exchange interaction involving Ni2+–O–Mn4+ and Mn3+–O–Cr3+, respectively. The variation in magnetic properties between the Ni-substituted and Cr-substituted samples is suggested to be due to the existence of different strengths of ferromagnetic interaction between Ni2+–O–Mn4+ and Mn3+–O–Cr3+. In addition, the deviation of the temperature dependence of the inverse magnetic susceptibility curves from the Curie-Weiss law suggests the existence of Griffith’s phase-like behaviour for both substitution samples. The Ni-substituted sample induced a greater GP effect than the Cr-substituted sample due to the larger difference of TC and TG value (TC-TG).