bluuebunny/crossref_metadata_2025 huggingface dataset:
Delineation of Groundwater Potential Zones in Rajkot Tehsil, Gujarat, Using Remote Sensing and GIS Techniques
Authors: Patel Jignasha
Published: April 2021

A Precious natural asset and prime natural resource for the basic need for a human is water. Groundwater which is commonly available as freshwater sources beneath the earth's surface is widely used in many parts of the world for domestic and agricultural activities. In this present work, the groundwater potential zone identification is done by using remote sensing and GIS. The thematic maps like soil, rainfall, drainage, DEM and land use land cover map has been used. The groundwater potential zone map is generated by assigning weightage to various thematic maps using weighted overlay analysis and the groundwater prospective zone of the study area was classified into 5 categories viz., very poor, poor, good, very good and excellent. The result depicts the groundwater potential zones in the study area and found to be helpful in better planning and management of groundwater resources.
Эстрогеноподобные вещества надземной части Ferula tschimganica
Authors: Маматханов Ахматхон Умарханович , Ахмедходжаева Хафиза Саидганиевна , Маматханова Мунирахон Ахматхон кизи , Халилов Равшанжон Муратджанович
Published: April 2021

Найдены оптимальные параметры, влияющие на процесс экстракции суммы сложных эфиров терпеноидных спиртов из надземной части Ferula tschimganica и очистки полученного экстракта, позволяющие в последующем получить конечную субстанцию без зеленой окраски. Разработана технология получения суммы сложных эфиров терпеноидных спиртов из надземной части Ferula tschimganica. Предложен спектрофотометрический метод количественного определения суммы сложных эфиров терпеноидных спиртов в субстанции чимфэстрола (рабочее название создаваемого средства). На основании фармакологических исследований установлено, что сложные эфиры терпеноидных спиртов из надземной части Ferula tschimganica в дозе 1 мг/кг проявляют выраженный эстрогенный эффект как в опытах на неполовозрелых, так и на овариэктомированных крысах, сопоставимый с аналогичным действием тефэстрола и мало уступающий эффекту синтетического эстрогенного препарата синэстрола.
Молекулярно-массовые характеристики и антикоагулянтная активность низкомолекулярного гепарина, полученного деполимеризацией азотистой кислотой
Authors: Юрьева Кристина Павловна , Фрумин Л. Е. , Баева Е. А. , Матвеев А. В. , Жаворонок Е. С. , Прохоров Д. И. , Гребенкина Л. Е. , Панов Алексей Валерьевич , Кедик Станислав Анатольевич
Published: April 2021

Деполимеризацией высокомолекулярного гепарина азотистой кислотой получен низкомолекулярный гепарин. Методом препаративной хроматографии из него выделены узкие по молекулярной массе фракции низкомолекулярных гепаринов, что подтверждено методом эксклюзионной ВЭЖХ. Средняя молекулярная масса продуктов, по данным капиллярной вискозиметрии, уменьшается за время синтеза (4 ч) с 14,0 до 3,4 кДа. Среди полученных продуктов выделены фракции, молекулярно-массовые характеристики, соотношение сульфо- и карбоксильных групп, а также специфическая активность которых соответствует показателям для низкомолекулярного гепарина, выделенного из промышленно выпускаемого препарата Фрагмин®. Показано, что в зависимости от продолжительности обработки высокомолекулярного гепарина азотистой кислотой в кислой среде возможно получение низкомолекулярных гепаринов, аналогичных по своим характеристикам субстанциям Дальтепарин и Надропарин.
Экспериментальая оценка дополнительной гормональной активности прегнанового гестагена гестобутаноила
Authors: Федотчева Татьяна Александровна , Шеина Н. И. , Паршин В. А. , Семейкин А. В. , Вотяков В. А. , Шимановский Н. Л.
Published: April 2021

Изучена способность прегнанового стероида с гестагенной активностью гестобутаноила оказывать глюкокортикоидное, минералкортикоидное, антиадрогенное, эстрогенное действие в эксперименте на крысах. Установлено, что гестобутаноил не обладал эстрогенной активностью, так как не увеличивал вес матки при длительном (30 дней) введении как в терапевтической дозе 0,25 мг/кг, так и в дозе, в 100 раз её превышающей. Гестобутаноил не проявлял глюкокортикоидной активности: при 30-дневном введении гестобутаноила в дозе 2,5 мг/кг масса тимуса не изменялась. Однако при введении в высокой дозе, в 100 раз превышающей терапевтическую (25 мг/кг), масса тимуса снижалась на 25 % (p ≤ 0,05). Гестобутаноил в дозе 2,5 мг/кг снижал экспрессию мРНК андрогенных рецепторов в матке крыс более чем в 3 раза и, как показано ранее, не увеличивал вес простаты и мышцы m. levatorani. При проведении исследования минералокортикоидной активности таблеток гестобутаноила при пероральном введении самкам крыс в дозах, превышающих терапевтическую в 100 и 1000 раз (2,5 и 25 мг/кг соответственно), в течение 14 дней не наблюдалось снижения диуреза во всех подопытных группах, не происходило задержки воды в организме крыс, электролиты выводились с мочой и присутствовали в моче в неизменной концентрации, что свидетельствует об отсутствии побочного минералокортикоидного действия таблеток гестобутаноила.
Qualidade de vida de estudantes de pós-graduação em Odontologia: uma análise por meio dos domínios do WHOQOL-bref
Authors: Teixeira Cinthia Nara Gadelha , Rodrigues Maria Imaculada De Queiroz , Silva Paulo Goberlânio De Barros , Barros Myrna Maria Arcanjo Frota , Alves Cláudia Maria Coêlho , Almeida Maria Eneide Leitão de
Published: April 2021

O objetivo do estudo foi avaliar a qualidade de vida (QV) dos estudantes de pós-graduação em Odontologia por meio dos domínios do World Health Organization Questionnaire for Quality of Life-bref (WHOQOL-bref). Trata-se de um estudo transversal, com 88 estudantes matriculados em um programa de pós-graduação em Odontologia. Os dados foram coletados entre junho e agosto de 2015, incluindo informações sociodemográficas e um questionário de qualidade de vida, o WHOQOL-bref. Foi realizada associação das informações sociodemográficas com os domínios do questionário utilizado e análise bivariada, seguida do modelo de regressão logística multinominal, sendo considerado significativo p0,05. A maioria (55,7%) dos estudantes foram classificados na categoria “satisfação” quanto à qualidade de vida. Entre os domínios, o maior escore encontrado foi para Relações Sociais (15,23 ± 2,72), e o menor para o Físico (12,82 ± 1,56). Houve associação da frequência da prática religiosa (p=0,046) e do ano da pós-graduação (p=0,025) com o domínio Físico; o sexo (p=0,016) e considerar-se religioso (p=0,008) com o domínio Psicológico; e o estado civil com os domínios Relações Sociais (p=0,017) e Meio Ambiente (p=0,008). A QV dos estudantes de pós-graduação em Odontologia foi mensurada na região de satisfação, podendo ser influenciada por fatores como religiosidade, ano da pós-graduação, sexo e estado civil.
Autonomia do Projeto Político Pedagógico: Considerações sobre uma escola rural de Jataí - GO
Authors: Porfírio Luciana Cristina , Lima Wanilda Pereira de
Published: April 2021

As indagações em torno do Projeto Político-Pedagógico (PPP) de uma escola rural em Jataí, interior do estado de Goiás, ancorou-se na premissa de que a escola amplia horizontes para o mundo do conhecimento, desde que a identidade cultural dos sujeitos que por ela passam sejam valorizadas. Na história da educação brasileira, a relação campo–cidade impactada por um passado colonial escravocrata, fez emergir no imaginário social que os espaços rurais e as pessoas que neles habitam são marcados pelo atraso. Projeção elaborada a partir de um mito que associava urbanidade e industrialização à modernidade e desenvolvimento. As pessoas do campo – negros africanos e indígenas escravizados, analfabetos da língua vernácula imposta pelos portugueses, bem como os imigrantes que os substituíram pós-abolição – produziram uma nova classe de miseráveis em um período em que não haviam políticas educacionais para essa população. A elite brasileira que se beneficiava diretamente das atividades agrícolas, desde o século XIX até o século XX, criou escolas para servir apenas sua própria classe social. Somente após a década de 1930 é que se criaram as escolas rurais, porém, como sendo um arremedo das urbanas, desconsiderando-se a população do campo e o contexto local. Daí a importância de se lançar o olhar sobre um PPP, oito séculos depois, identificando a identidade rural local ali expressa.
Developing Data-Driven Administrative Policy for International Montessori Center, Thailand
Authors:   St. Theresa International College, Thailand, Ali Arisara , Pa-alisbo Mark Anthony C.
Published: April 2021

This institutional survey research was used to improve administrative policies at International Montessori Center (IMC), a private international kindergarten in Bangkok, Thailand. The main goal of the study was to gather input from school stakeholders regarding daily conditions and functions, with the ultimate goal of improved administrative policy implementation. A literature review indicated no direct prior research. A survey gathered input from four stakeholder groups, including 15 teachers, 104 parents, 17 staff, and 3 administrators, regarding Physical Safety, Child Sense of Being Valued (classroom atmosphere), Classroom Conditions, Information Availability, Parent-Teacher Meeting Quality, Administrative Support, Parental Support (overall), Educational Tools and Technology, Quality of Peer Professional Relationships, and Availability of Needed Supplies. Stakeholders rated the daily operations areas using five-point Likert-style questions and responded to two open-ended questions. In sum, findings highlighted a number of useful perspectives for the little-studied early-childhood administrative community: a) seemingly mundane school functions are important to those who experience them on a regular basis; b) all stakeholder input is valuable when gathering school daily operations feedback; c) similarities and differences in stakeholder input help administrators develop a more holistic perspective of school functioning; and d) stakeholder input is a valuable tool for administrators to use when critically considering responsive policy formulation. Conclusions reached were limited to correlations and patterns found in one institution. However, it is clear that this original research is a valuable step in improving administrative policy implementation at the private international kindergarten level.
TEORIA DA PÓS-AVALIAÇÃO DA APRENDIZAGEM: UM OLHAR SOBRE A EVASÃO ESCOLAR
Authors: Ribeiro da Graça Margeylson , Batista do Sacramento Crislaine
Published: April 2021

A avaliação da aprendizagem é um assunto discutido amplamente. Basta uma consulta nos principais banco de publicações para se elencar o quantitativo das publicações. Através dessa pesquisa pode-se notar que o conjunto de pontos necessários ao docente após a avaliação da aprendizagem e antes da retomada da aula, carece de material teórico. Desta forma, utilizando como respaldo as contribuições de Jussara Hoffman, Cirpiano Luckesi, Pedro Demo, Mourão, dentre outros, foi montado um arcabouço sobre a avaliação a fim de justificar a existência de um momento após a avaliação que precisa ser pesquisado. Apresenta-se também uma breve relação do que a teoria da pós avaliação pode influenciar em alguns aspectos que colaboram para a evasão escolar. Para compor a teoria, foram utilizadas o estado da arte, pesquisa bibliográfica e quali-quantitativa como metodologias de pesquisa. Por fim, apresenta-se a carência de estudos sobre o momento após a avaliação da aprendizagem e antes da retomada do ensino, ponto este que influencia numa educação mais justa, que não preze pela manutenção das desigualdades e das injustiças sociais. PALAVRAS-CHAVE: Aprendizagem. Avaliação. Evasão. Pós-Avaliação.
Identifying Psychosocial Variables of the Interactive Mobile Interface for Geriatric Persons
Authors: Ngaruiya Njeri , Orwa Daniel , Wagacha Peter
Published: April 2021

This is qualitative
exploratory research that looked into the gap between gerontechnology and
psychosocial wellness. The physical and psychological wellness of geriatric
persons has been developed over the few decades. This has made older people
consumers of the different technologies. This, though, is not satisfactory
enough as the older generation yearns for the worth and sense of belonging that
existed in the traditional world, with the different roles that they played.
With the modernization and the recent pandemic, it distances the older persons
from their loved ones and society, therefore, disengaging from
activities.

This research identified
this gap, and under a research protocol from a legally authorized organization
in Kenya, we approached a philanthropic social home and a community-based daycare
where eight participants gave verbal informed consent to take part in the 10-week
study
Design and manufacture of the Torque test setup for small and shapeless materials
Authors: COŞKUN Zeliha , ÇELİK Talip , KİŞİOĞLU Yasin
Published: April 2021

In this study, the design and manufacture of torque test set up has been carried out for small and shapeless speciment. The torque sensor, which has maximum 10 Nm, is used in the test system design. The certain specification of Nema 34 step motor which use to apply torsional force to the specimens is 12 Nm, 24V and 4.2 ampere. The step motor is controlled by the HY- DIV268N-5A Step Motor Driver and the supply voltage of driver is 24 Volts. The information about the degree of the specimen rotation was taken from potantiometer. The information obtained from the sensor and potentiometer was transferred to the LabVIEW software to be representation graphically using the USB 6003 DAQ card. The first metatarsal bone modelled from computerized tomography (CT) images was produced by Ultimaker2 3D printer using polylactic acid (PLA) material. The printed bone model was tested through torsion test set up. At the same time, the 3D bone was prepared for finite element analysis. Boundary conditions were applied in the finite element analysis (FEA) model in accordance with the test setup. The produced bones using 3D printer were subjected to torsion test with the test setup. Also the modelled bone was tested in accordance with the torsion test setup by using finite element analysis. After that, the FEA and experimental test results were compared with each other. As a conclusion, the optimization of the torsional test setup was performed based on the FEA.
REGULATION OF CEREAL EMBRYONIC ORGANOGENESIS IN VITRO CONDITIONS
Authors:   Ufa Institute of Biology of the Ufa Federal Research Centre of the Russian Academy of Sciences, Kruglova N.N.
Published: April 2021

The article provides the brief review of the literature and own works devoted to the peculiarities of the cereal embryonic organogenesis at the early stages of ontogenesis in the conditions of in vitro culture (the so-called somatic embryogenesis, or embryoidogenesis in vitro). Particular attention is paid to the issues of hormonal regulation of the development of somatic cereal embryos from initial cells to mature structures in vitro. A comparison of somatic embryogenesis in vitro with similar events in zygotic embryogenesis in vivo confirms the validity of the principle of universality of morphogenesis processes in vivo and in vitro (Batygina, 2014). The prospects of using somatic embryogenesis in vitro as a model for studying the most complex biological phenomenon – zygotic plant embryogenesis in vivo – are discussed.
Metode Dakwah Perspektif Quraish Shihab (Analisis Terhadap QS. Al Nahl: 125 – 128 Dalam Tafsir Al Misbah)
Authors: Syahputra Afrizal El Adzim
Published: April 2021

Dakwah merupakan salah satu bentuk usaha atau ajakan kepada individu maupun masyarakat agar menjadi manusia yang lebih baik dan sempurna. Dakwah merupakan salah satu ajaran agama Islam yang diwajibkan kepada para pemeluknya. Keberhasilan dan ketidaksuksesan dalam berdakwah dilatarbelakangi oleh skill dan kreatifitas para pendakwah dalam memilih beberapa metode yang tepat. Karena itu, dalam al Qur’an terdapat ayat yang menjelaskan metode tersebut, diantaranya adalah pada surah al Nahl: 125 – 128. Menurut Quraish Shihab, ayat 125 berisi tentang metode menghadapi sasaran dakwah yang diduga dapat menerima dengan mudah, sedangkan ayat 126 – 128 berisi tentang metode menghadapi sasaran dakwah yang membangkang dan melakukan kejahatan terhadap para pelaku dakwah atau penganjur kebaikan. Dengan dikajinya topik ini, diharapkan dapat menambah wawasan tentang metode dakwah perspektif ulama nusantara.
Studi: Kasus Asuhan Keperawatan Jiwa Pada Tn.M Dengan Masalah Halusinasi Pendengaran Di Jl. Sipodang Kec. Sosorgadong Di Lingkungan Masyarakat
Authors: RutinaPasaribu
Published: April 2021

Halusinasi merupakan hilangnya kemampuan manusia dalam membedakan rangsangan internal (pikiran) dan rangsangan eksternal (dunia luar). Pasien dengan halusinasi mendapatkan respon tentang lingkungannya tanpa ada objek rangsangan yang nyata. Sebagai contoh pasien mengatakan mendengar suara padahal kenyataannya tidak ada orang yang berbicara. Orang dengan gangguan kejiwaan memiliki kecenderungan menjadi penyendiri/mengisolasi diri dari dunia luar. Mereka kesulitan bersosialisasi dengan orang lain. Banyak dari mereka merasa mendengar suara / bisikan yang bisa mempengaruhi mereka menjadi pemarah, melakukan kekerasan, dan bahkan bisa melakukan bunuh diri.
Nanomedicine has elegantly attempted to cure multiple gene polymorphisms and mutations in cardiovascular diseases using gene therapy techniques.
Authors: Dowaidar Moataz
Published: April 2021

The molecular mediators that induce MI, the loss of myocardial regeneration, and the development of heart disease are all being researched more thoroughly. It's intriguing to think about how genetic factors could be used to modulate these disease mediators. DNA, RNA, or proteins may both be included in this operation. However, direct delivery of these biomolecules is not always effective. Using gene therapy methods, nanomedicine has elegantly attempted to reverse many gene polymorphisms and defects in complex diseases.The stability of these biomolecules, as well as their controlled release and passage through barriers to the operating site, can be aided by delivery systems. Precision-tailored vector delivery has been shown to reduce toxicity and improve drug availability. Currently, a variety of distribution systems are being evaluated, with the frontrunners incorporating security and conclusions being selected.New biological mediators, as well as the complex interactions within them, as well as their pharmacokinetic and pharmacodynamic profiles, will be discovered in the future. This opens the door to a more advanced delivery system that meets the biological requirements for maximum therapeutic efficacy.
Thủ tướng Chính phủ nước CHXHCN Việt Nam Phạm Minh Chính
Authors: Si H.L. Cu
Published: April 2021

Phạm Minh Chính (sinh ngày 10 tháng 12 năm 1958) là một lãnh đạo của Đảng Cộng sản Việt Nam, Nhà nước Việt Nam, tướng lĩnh Công an nhân dân Việt Nam và chính trị gia người Việt Nam. Ông hiện là Thủ tướng Chính phủ nước Cộng hòa xã hội chủ nghĩa Việt Nam, Ủy viên Bộ Chính trị Ban Chấp hành Trung ương Đảng Cộng sản Việt Nam khóa XIII, Trưởng ban Tổ chức Trung ương, Trưởng Tiểu ban Bảo vệ Chính trị Nội bộ Trung ương Đảng Cộng sản Việt Nam, Đại biểu Quốc hội Việt Nam khóa XIV.
Different insulin resistance and inflammation pathways are influenced by genetic factors in metabolic syndrome. Gene therapy enables early recognition and treatment of the genetic factors.
Authors: Dowaidar Moataz
Published: April 2021

Often known as central obesity, adiposity, and being diagnosed with MetS areall three signs of the same. Different types of insulin resistance andinflammatory pathways are under the control of the control of genes. If more isknown about the relative importance of lipotoxicity and inflammation, furtherstudies are needed. Despite its controversial nature, CRIS (a newer, specializedtechnique than CRISPR) holds enormous promise for the future benefit of theentire scientific community and patient populations.As a result of thebreakthroughs in genome editing, the therapeutic area for cardiovascular diseaseis broadening. The research recommends that the faster treatment of humanaspects of this disease is completed, the better, she adds. These targeting andCRIS editing, the same enzymes, and the resulting edit types, use the samedelivery process would apply the same off-target effects. If we developed aCas9 protein that had already been engineered and built by a bacterial enzymes,we would still have to be very vigilant about its use.
Digital Business What's Next
Authors: Wicaksono Hendro
Published: April 2021

The presentation gives a brief introduction to industrial revolutions and their enabling technologies, entrepreneurship types, and leadership transformation. It also explains the transformation of business models and disruptions in different sectors due to the innovative implementation of new technologies.
POPY AMALIA PAVITRA_130119040_ESDM KP B
Authors: PAVITRA POPY AMALIA
Published: April 2021

Indonesian business competition in the era of 4.0 has flocked to prepare to improve human resource development to advance in the global market. This is certainly a smart thing for company leaders to take new steps in the era of technological developments with shifting demographic patterns. That it will be experience changes in the science-based economy in increasing the urge to continue to innovate. In the last 3 years, the Indonesian economy has grown to more than 5% and for Pandemic COVID-19 2020 will be at the 6% level. The government has committed to building the global competitiveness of the manufacturing industry in accelerating the implementation of industry 4.0. In the fourth wave of the industrial revolution era, it requires connections and interactions with integrated technology intervention, information and communication in order to achieve efficiency and product quality improvement of productivity. Business of towards competition in this global market is in the form of superiority in the use of technology that leads to efficiency. Industry 4.0 is characterized by the use of information technology, artificial intelligence, and automatic machines or vehicles since 2011.
Differential expression of ECT2 in cancers of the breast.
Authors: Mamoor Shahan
Published: April 2021

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer. We report here significant differential expression of the gene encoding epithelial cell transforming 2, ECT2, when comparing primary tumors of the breast to the tissue of origin, the normal breast. ECT2 was also differentially expressed in the tumor cells of patients with triple negative breast cancer. ECT2 mRNA was present at significantly higher quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of ECT2 in primary tumors of the breast was correlated with overall survival in patients with basal and luminal A subtype cancer, but in a contrary manner, demonstrating a complex relationship between correlation of primary tumor expression with overall survival based on molecular subtype. ECT2 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
Cardiometabolic conditions could be related to vitamin D deficiency. The genetic determinants that affect vitamin D pathways may be solved with nanomedicines.
Authors: Dowaidar Moataz
Published: April 2021

Vitamin D deficiency is a risk factor for cardiometabolic disorders.Nanomedicines can be used to treat atherosclerosis and associated ischemicdisorders. They are able to reduce internal clearance pathways and prolongblood circulation. They also have a large surface size and more sensitive andvaried reactivity than bulk materials, making them more effective at targetingand functionalizing nanoparticles for various types of disease. This studyfocuses on the specialized use of nanomedicine for atherosclerotic diseases inpreclinical and clinical practice. It presents the most recent developments innanomedicine-based treatment regimens for the disease. It has the potential tosolve the genetic determinants that influence vitamin D pathways.
IDENTIFIKASI LEBAH DAN KUPU POLINATOR DI HUTAN BILLA BATTANG KOTA PALOPO
Authors: Amrullah Syarif Hidayat
Published: April 2021

Penelitian ini bertujuan untuk (1) menginventarisasi jenis lebah yangberperan sebagai polinator di Hutan Billa Battang; dan (2) menginventarisasi jeniskupu yang berperan sebagai polinator di Hutan Billa Battang. Hasil inventarisasitersebut digunakan untuk mengenali jenis serangga polinator yang sangatmembantu proses penyerbukan tanaman (entomogami), sehingga nantinyaterdapat kontrol bagi para pembudidaya hasil hutan untuk tidak melakukanpenangkapan lebih dan aktivitas lain yang dapat mengancam populasi polinatortersebut. Penelitian dilakukan di dua tempat; di Hutan Billa Kelurahan Battangdan identifikasi spesimen di Laboratorium Sel dan Jaringan Fakultas SainsUniversitas Cokroaminoto Palopo. Jenis penelitian yang dilakukan adalahpenelitian deskriptif dengan metode pengambilan sampel lebah serta kupudilakukan dengan teknik jelajah menyusuri kawasan hutan. Penangkapandilakukan dengan menggunakan sweep net. Setelah diidentifikasi, sampelkemudian diawetkan untuk koleksi dalam bentuk insektarium. Hasil penelitianmenunjukkan 16 jenis polinator yang terdiri dari 3 jenis lebah dan 13 jenis kupu.Keragaman jenis polinator di tiga lokasi pengamatan dalam Hutan Billadikarenakan perbedaan struktur habitat, jenis bunga tanaman, serangga predatorsebagai musuh alami, serta parameter fisik berupa temperatur dan intensitascahaya.
COMPANIES IN INDONESIA DURING GLOBAL ECONOMIC DISRUPTIONS
Authors: dharma Muhammad aji
Published: April 2021

companies in Indonesia to survive in the midst of global economic
What genomic research has told us about the obesity and its possible gene therapy targets.
Authors: Dowaidar Moataz
Published: April 2021

The discovery of a genome-wide correlation with obesity-related genes hasrevealed new information about the genetics of obesity. Given the lowproportion of obesity heritability explained by available SNPs, it's not shockingthat these SNPs aren't scientifically effective as methods for assessing whowould acquire obesity. The roles of the majority of loci, the majority of whichmap to non-coding sequences, will take thorough analysis to determine theresponsible gene at each locus, which may not be the closest gene. Thismechanistic information, as well as the resulting elucidation of thepathophysiology of obesity, will allow the creation of new therapies, whichcould be the primary advantage of these genetic discoveries.Fortunately, a lack of mechanistic information hasn't stopped researchers fromusing SNPs and genetic risk ratings to shed light on how obesity biologyinteracts with environmental and lifestyle influences. These findings suggestthat an unhealthy lifestyle may amplify the genetic risk of obesity, despite thefact that environmental studies of obesity genes may be distorted byinaccuracies in diet and physical activity measurement. More research isrequired to confirm this theory and to identify the specific dietary components(such as sugar-sweetened beverages) that interfere with genetic variants. Thisstudy could contribute to personalized obesity prevention and care measures inthe future (pending confirmation in clinical trials of genetic-risk-guidedinterventions). Obesity genetics has offered researchers the opportunity toexamine causal interactions between obesity and its various possiblecomplications. However, since the majority of the studies discussed above wereconducted on people of European ethnicity, more research is required inminority ethnic groups with a high risk of obesity to understand the role ofbiology, climate, and relationships among these factors in explaining theirincreased risk.
The Generalization of the Periodic Table. The "Periodic Table" of "Dark Matter"
Authors: Penchev Vasil Dinev
Published: April 2021

The thesis is: the “periodic table” of “dark matter” is equivalent to the standard periodic table of the visible matter being entangled. Thus, it is to consist of all possible entangled states of the atoms of chemical elements as quantum systems. In other words, an atom of any chemical element and as a quantum system, i.e. as a wave function, should be represented as a non-orthogonal in general (i.e. entangled) subspace of the separable complex Hilbert space relevant to the system to which the atom at issue is related as a true part of it. The paper follows previous publications of mine stating that “dark matter” and “dark energy” are projections of arbitrarily entangled states on the cognitive “screen” of Einstein’s “Mach’s principle” in general relativity postulating that gravitational field can be generated only by mass or energy.
Fascism: Left, Right, or Neither
Authors: Gindler Allen
Published: April 2021

The article discusses fascism's place on the political spectrum. At present, there is no consensus among political scientists and economists on that issue, as it has been extraordinarily politicized and distorted during ideological struggles among various currents of socialism. From the very beginning, fascism was depicted by Marxists as belonging to the Right, while Fascists themselves wanted to build a society that transcends the Left-Right paradigm. However, few voices in academia have noted that practical implementation of the fascists’ ideas, inherited from the works of revolutionary and national syndicalists, exhibited predominantly leftist characteristics.The ambiguity of placing fascism in its proper place on the political spectrum can be confidently resolved by applying three primary factors that govern political spectrum polarization: attitude to private property, scope of individual freedom, and degree of wealth redistribution. The article argues that fascism is a particular current of non-Marxian socialism that utilized collectivization of consciousness and wealth redistribution as the main paths toward socialism rather than outright expropriation of private property or means of production. Simultaneously, it is acknowledged that private property rights were inhibited by the fascist state, even though de jure they were permitted.The fascist ideal of the “alternate way” had a logical inconsistency that produced an unstable equilibrium between labor and capital as well as between the man and the state. The politico-economic structure predictably collapsed to the left in the course of building a new society. Therefore, fascism could be correctly called the Right of the Left.
Topla at the Beginning of the XVIII Century
Authors: Elezovic Dalibor
Published: April 2021

The research aims to point out how Venice incorporated Topla into its administrative system. Although the settlement came under Venetian control at the time of the conquest of Herceg Novi in 1687, despite several unsuccessful attempts, this area was fully integrated after the conclusion of peace in 1699 with the Ottoman Empire. Thus, the legal relations concerning the property rights over real estate were regulated in a way acceptable to Venetian interests. The paper is based on the published Cadastre of Herceg Novi and Risan from 1704 and the literature. The mentioned Cadastre reveals in full light how the Venetian government, accepting the real situation as a consequence of the Morean War (1684–1699), integrated the Topla area into its administrative apparatus.
The cross-sectional average inequality in lifespan (CAL†): A lifespan variation measure that reflects the mortality histories of cohorts
Authors: Nepomuceno Marília , Cui Qi , van Raalte Alyson A , Aburto José Manuel , Canudas-Romo Vladimir
Published: April 2021

Lifespan variation is a key metric of mortality that describes both individual uncertaintyabout the length of life and heterogeneity in population health. We propose a novel andtimely lifespan variation measure, which we call the Cross-sectional Average Inequality in Lifespan. This new index provides an alternative perspective on the analysis of lifespan inequality by combining the mortality histories of all cohorts present in a cross-sectional approach. We demonstrate how differences in the Cross-sectional Average Inequality in Lifespan measure can be decomposed between populations by age and cohort to explore the compression or expansion of mortality in a cohort perspective. We apply these new methods using data from ten low-mortality countries from 1879 to 2013. The Cross-sectional Average Inequality in Lifespan measure reveals greater uncertainty in the timing of death than the period life table-based indices of variation indicate. Also, country rankings of lifespan inequality vary considerably between period and cross-sectional measures. These differences open intriguing questions as to which temporal dimension is the most relevant to individuals when considering the uncertainty in the timing of death in planning their life courses.
Direct selling strategies and customers loyalty in the Nigerian deposit money banks
Authors: Uzochukwu OKORO
Published: April 2021

Direct Selling has become a veritable part of business success story particularly in the deposit money bank of Nigeria. The main objective of this study is to examine the effect of direct selling strategies on customers loyalty in the Nigerian deposit money banks. Primary data was used for the study. The data were collected through a structured questionnaire. The study adopted the cross-sectional survey research design method. The population of the study was 812 employees from selected deposit money banks (Zenith Bank, GTBank, UBA, First Bank and Fidelity Bank) in Delta State. A total number of 260 respondents were selected as the sample size. To validate the instrument, face and content validity were adopted. To verify the reliability of the research constructs, the internal consistency analysis and item-to-total correlation was applied to identify the internal consistency reliability of the constructs. Descriptive statistics were used to analyze the responses of the respondent background profile and also to reveal the pattern of responses from each of the constructs in the sub-scale. Multiple regression analysis was adopted to analyze the effect of the variables of direct selling strategies on customers loyalty.
ANTENA TRACKER TELEVISI SATELIT DENGAN ALGORITMA MATEMATIS SEBAGAI PREDIKSI KOORDINAT
Authors: Pradipta Hanif , Joni Koko , Ubaidillah Achmad , Ibadillah Achmad Fiqhi
Published: April 2021

Satelit merupakan sebuah trobosan terbaru dalam proses pengiriman data. Satelit dapat digunakan untuk memantau keaadaan atmosfer bumi, navigasi, maupun komunikasi data jarak jauh sebagai contoh broadcast televisi Pada dasarbya antena penerima akan diarahkan secara manual oleh pengguna agar pengarahan antena tepat menuju posisi satelit broadcast televisi sesuai dan mudah, maka dapat digunakannya perangkat berupa antena tracking. Untuk mendapatkan posisi koordinat satelit digunakan perhitungan algoritma matematis. Penelitian ini penulis menggunakan satelit MEASAT-3A dengan hasil perhitungan pada waktu 1 Januari 2021 pukul 00:00:00 didapatkan posisi satelit terletak pada koordinat latitude -0,0232174734074105°, longitude 91,8487688254899° dan altitude 35784, 6417029739 Km. Posisi dari antena tracker berada pada koordinat latitude -7.128558069°, longitude 112.725319020 dan altitude 0.0300 Km. Didapatkan arah putar dari antena tracker berupa nilai azimuth 288,7960234° dan elevation °. keberhasilan dari pergerakan sudut putar antena tracker terhadap SetPoint sudut Azimuth  dan Elevation sebesar 9,74380501% dan 99,86132262%.
Naphazoline Nitrate, Bisacodyl and Guttalax Treat Microwave Sonic Effects
Authors: Skopec Robert
Published: April 2021

At the end of the December 2018 we have found a medicine fully treating the damages caused the Frey Effect of Microvawe and other types of Sonic Weapons in Human’s internal, endogenous organs. I am proposing to use Naphasoline nitrate, (former) nasal decongestatnt, to treat Carcinogenesis of the Human’s internal, endogenous organs caused by Sonic Weapons through the release and cleaning of the Lymphatic ways in patients with colorectal, colon, pancreatic, breast, etc., cancer. I have proved this healing effect of the Naphazoline nitrate on Myself during treatment in last months of the year 2018. Naphazoline Nitrate, Bisacodyl and Guttalax are clearing the Pylorus in human digestive system and treat so the Microwave Sonic Effects.
Magic Targets for Magic Bullets
Authors: Pak Vladimir
Published: April 2021

The “magic bullet” by Paul Ehrlich is a chemotherapeutic, which can precisely locate and destroy tumor cells. For over 100 years, a great number of approaches have been developed for targeted delivery of toxins. Nevertheless, the progress in the battle with cancer is moderate. In reality, the magic bullet is unable to destroy cancer cells with 100% efficacy. However, cancer cells are neither an optimal nor the only possible target. The magic bullet needs a “magic target”.
Nasopharyngeal Carcinoma in Children: Experience of Pierre& Marie Curie Center
Authors: Ezziane K.Ezziane
Published: April 2021

A retrospective study was undertaken on 50 patients in pediatric age group with diagnosis of nasopharyngeal carcinoma (UCNT) in children, treated from 2008 to 2013 on our oncologic center. For all the patients, the diagnosis was made after surgery. All patients received adjuvant chemotherapy. The combined modality of chemotherapy and radiotherapy results is satisfactory for loco regional control and survival and acceptable for toxicity in patients with nasopharyngeal carcinoma in pediatric age group.
Traffic optimization applying machine learning methods
Authors: Alekseeva D. , Marochkina A. , Paramonov A.
Published: April 2021

Future networks bring higher communication requirements in latency, computations, data quality, etc. The attention to various challenges in the network field through the advances of Artificial Intelligence (AI), Machine Learning (ML) and Big Data analysis is growing. The subject of research in this paper is 4G mobile traffic collected during one year. The amount of data retrieved from devices and network management are motivating the trend toward learning-based approaches. The research method is to compare various ML methods for traffic prediction. In terms of ML, to find a solution for a regression problem using the ensemble models Random Forest, Boosting, Gradient Boosting, and Adaptive Boosting (AdaBoost). The comparison was based on the quality indicators RMSE, MAE, and coefficient of determi-nation. In the result Gradient Boosting showed the most accurate prediction. Using this ML model for mobile traffic optimization could improve network performance.
Perbandingan Penggunaan Platform Google Classrom dan Grup Whatsapp Dalam Pembelajaran Online Selama Pandemi Covid-19
Authors: Endah Yuliani  , Romadhiyana Kisno Saputri
Published: April 2021

Dampak dari adanya pandemi COVID-19 pada sistem pendidikan di Indonesia adalah seluruh kegiatan pembelajaran dilaksanakan di rumah masing-masing melalui aplikasi yang tersedia. Pembelajaran online dilakukan melalui berbagai platform seperti google classroom  dan grup whatsapp. Pelaksanaan pembelajaran online perlu menggunakan platform yang mampu menunjang ketecapaian tujuan mata kuliah, untuk itu, perlu diketahui platform mana yang mampu menunjang ketercapaian tujuan mata kuliah sehingga hasil belajar juga baik. Penelitian ini bertujuan untuk membandingkan hasil belajar yang menggunakan platform google classroom dan grup whatsapp dan seberapa efektifnya kedua platform tersebut selama pandemi COVID-19. Jenis penelitian yang dilakukan pada penelitian ini adalah penelitian quasi experiment dengan desain pretest-postest nonequivalent multiple-group design. Populasi dalam penelitian ini adalah seluruh mahasiswa semester 2 yang mengikuti pembelajaran online dengan google classroom dan grup whatsapp. Sampel pada penelitian ini berjumlah 48 mahasiswa yang terbagi menjadi 2 kelompok sesuai perlakuan dengan jumlah masing-masing kelompok 24 mahasiswa. Data hasil belajar mahasiswa diperoleh dari hasil pre test, yaitu nilai Ujian Tengah Semester sebelum dilaksanakan pembelajaran online dan nilai post test, yaitu nilai Ujian Akhir Semester setelah dilaksanakan pembelajaran online pada kedua kelompok perlakuan, data kemudian diolah dengan menggunakan bantuan software Microsoft Excell dan SPSS 25 Hasil penelitian menunjukan bahwa hasil belajar kedua kelas sama sebelum diberi perlakuan dan hasil belajar kedua kelas berbeda setelah diberi perlakuan atau dengan kata lain kelas yang menggunakan platform google classroom  lebih baik dari pada kelas yang menggunakan platform grup whatsapp. Pembelajaran dengan platform google classroom  lebih efektif daripada dengan platform grup whatsapp.
Pembentukan Karakter Siswa Pada Pembelajaran Bahasa Indonesia Berbasis Kearifan Lokal
Authors: Irfan Muh. , Firmansyah Edi , Nasruddin Nasruddin , Setiyadi Muhammad Wahyu
Published: April 2021

Penelitian ini bertujuan mendeskripsikan pembentukan karakter siswa pada pembelajaran bahasa indonesia berbasis kaarifan lokal. Pendekatan yang digunakan adalah kualitatif dan kuantitatif dengan jenis deskriptif. Subjek penelitian ini yaitu 32 siswa MAN Dompu. Data diperoleh melalui angket jenis Skala Likert. Hasil penelitian menunjukan bahwa pada pembelajaran bahasa indonesia yang berbasis kearifan lokal dapat meberikan dampak yang sangat positif terhadap pembentukan karaker siswa. Pernyataan tersebut didasari oleh hasil analisis data yang mengungkapkan bahwa pada setiap indikator pembentukan karaker siswa yaitu: 1) Jujur dengan perolehan skor rata-rata sebesar 2,35 dan kategori cukup baik; 2) Kreatif dengan perolehan skor rata-rata sebesar 2,53 dan kategori cukup baik; 3) Tanggung Jawab dengan perolehan skor rata-rata sebesar 2,51 dan kategori baik; dan 4) Toleransi dengan perolehan skor rata-rata sebesar 2,62 dan kategori baik, menunjukan bahwasanya siswa memiliki tingkat karakter yang cukup baik atau positif pada pembelajaran bahasa indonesia berbasis kearifan lokal yang terlihat pada masing-masing indikator.
Numerical Investigations of Virus Transport Aboard a Commuter Bus
Authors: Rahai Hamid , Bonifacio Jeremy
Published: April 2021

The authors performed unsteady numerical simulations of virus/particle transport released from a hypothetical passenger aboard a commuter bus. The bus model was sized according to a typical city bus used to transport passengers within the city of Long Beach in California. The simulations were performed for the bus in transit and when the bus was at a bus stop opening the middle doors for 30 seconds for passenger boarding and drop off. The infected passenger was sitting in an aisle seat in the middle of the bus, releasing 1267 particles (viruses)/min. The bus ventilation system released air from two linear slots in the ceiling at 2097 cubic feet per minute (CFM) and the air was exhausted at the back of the bus. Results indicated high exposure for passengers sitting behind the infectious during the bus transit. With air exchange outside during the bus stop, particles were spread to seats in front of the infectious passenger, thus increasing the risk of infection for the passengers sitting in front of the infectious person. With higher exposure time, the risk of infection is increased. One of the most important factors in assessing infection risk of respiratory diseases is the spatial distribution of the airborne pathogens. The deposition of the particles/viruses within the human respiratory system depends on the size, shape, and weight of the virus, the morphology of the respiratory tract, as well as the subject’s breathing pattern. For the current investigation, the viruses are modeled as solid particles of fixed size. While the results provide details of particles transport within a bus along with the probable risk of infection for a short duration, however, these results should be taken as preliminary as there are other significant factors such as the virus’s survival rate, the size distribution of the virus, and the space ventilation rate and mixing that contribute to the risk of infection and have not been taken into account in this investigation.
Open Awareness: Holding the Liminal Space in Transpersonal Coaching and Therapy
Authors: Dangeli Jevon , GELDENHUYS HENNIE
Published: April 2021

“Holding The Space” is the metaphorical container for the therapeutic interaction between the coach or therapist and client. Although the held space is largely intuitive, transpersonal practitioners who wish to teach, apply and develop its practice are faced with the challenge of reproducing it consistently and intentionally. Some important aspects of the held space include energetic resonance and rapport, a participatory perspective, mindfulness, intentionally cultivated attitudes of acceptance, compassion and interconnectedness, and induction of a state of awareness of wider perspective and receptivity. We propose a unique mode of mindful perception ideally suited to Holding The Space, called “Open Awareness”. The characteristics of this state are a mindful mode of perception; metacognitive introspective awareness; extrospective and somatic awareness; a reframe of personal identification leading to a sense of interconnectedness; and a fluid, dynamic balance between conscious focus and peripheral awareness. Open Awareness is simple enough to learn and apply quickly, and profound enough to evolve consciousness through regular practice. In general, the process begins with a shift of awareness to the physical senses, expansion and deepening to more subtle mental objects, and intentional resonance with the metaphorical space in between people and objects. The expansion of awareness is both inward (deep personal) and outward (interpersonal and transpersonal). Open Awareness is a distinct state, but shares characteristics with other disciplines such as Open Focus, Open Monitoring, Focused Attention meditation, and Focus-defocus practice. We advocate Open Awareness as a useful tool for coaches and therapists and suggest research to develop further applications. KEYWORDS Holding the Space, Transpersonal Coaching, Transpersonal Therapy, Mindfulness, Open Awareness.
Interactive Meditation Practice as Research Method: An Introduction to Embodied Spiritual Inquiry
Authors: Sohmer Olga R.
Published: April 2021

This article presents Embodied Spiritual Inquiry (ESI), a participatory approach to integral education and transpersonal research that has been offered since 2003 as a graduate course at the California Institute of Integral Studies (CIIS), San Francisco, by core faculty Jorge N. Ferrer. Inspired by elements of participatory research (e.g., Reason, 1994a; Reason & Bradbury, 2008) and cooperative inquiry (Heron, 1996), ESI applies Albareda and Romero’s Interactive Embodied Meditations (Ferrer, 2003) to access multiple ways of knowing (e.g., somatic, vital, emotional, mental, spiritual) and mindfully inquire into collaboratively decided questions about the human condition. Past inquiries have included diverse psychospiritual topics including the experiential features of relational spirituality (Osterhold, Husserl, & Nicol, 2007), the nature of human boundaries within and between co-inquirers (Sohmer, Baumann, & Ferrer, 2018), felt-sensed markers discerning genuine versus unreliable spiritual knowledge, experiential understandings of the personal and collective “shadow,” and the multidimensionality of the human condition. After presenting an overview of the ESI methodology and two case studies, this article discusses the merits, limitations, and future horizons of this approach for integral education and transpersonal research. KEYWORDS Transpersonal Research, Integral Education, Multiple Ways of Knowing, Interactive Embodied Meditations, Cooperative Inquiry, Participatory Research, Embodied Spirituality.