bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengelolaan Pendidikan Anak Usia Dini (PAUD) di TK Pelangi Kota Jambi
Authors: Anggraini Liza , Rianti Eka , Idris Addayan Muhammad , Junhaniah Rts. Ririn , Ramadani Desrilla , Chairunnisa R.  Radhiah , Nur Permadi Anggi , Yapi Akbar Maulan
Published: May 2023

Basically the implementation of Early Childhood Education is very important in the State of Indonesia because it aims to form a complete human personality, namely to form character, character, intelligence, skills and have devotion to the Almighty God. Early Childhood Education begins with family education, this is meant to be education from parents or other parties closest to the child himself. From various educational institutions, PAUD can provide the best service for the people as well as policy makers, starting from the central government to regional governments. In this research the researcher uses qualitative research, because the researcher will try to tell and understand the facts or descriptions according to the phenomena in the field without exercising hegemony over the conditions that occur. This study aims to find out the vision, mission and goals of PAUD, to find out the management carried out by this PAUD, to find out the implementation of the programs that have been made to achieve the vision, mission and goals of PAUD. The management of PAUD in Pelangi Kindergarten is enough good. Where the kindergarten already has a clear organizational structure, the vision and mission offered are also attractive, and have reliable teachers.
Pangeran Diponegoro Pahlawan Nasional dalam Novel Remy Sylado sebagai Sumber Belajar Sejarah
Authors: Siregar Isrina , Kurniawati Wahyuningtyas
Published: May 2023

The quality of education in Indonesia is declining, one of the reasons is that character education is still not optimal in schools, history learning resources so far have only used artifacts and other historical relics. Even though in the process of learning novels can be used as a source of learning history. Characters in historical novels can be used as a tool for instilling student character values. The method used in this study is a qualitative method with a historical or historical approach. The main data source used in this research is the novel Prince Diponegoro by Remy Sylado, published by Tiga Serangkakai. This study found several character values contained in the Prince Diponegoro novel, namely religion, nationalism values (love of the motherland), social care values, and cultural values. The value of character education can be used as a source of learning history that can be collaborated in basic competencies in class XI high school, namely 3.6 Analyzing the role of national and regional figures in fighting for Indonesian independence.
Pengembangan Kurikulum Muatan Lokal Berbasis Budaya Ungkapan Prolog Bahasa Melayu Jambi sebagai Mata Kuliah Ciri Kedaerahan pada Program Studi Pendidikan Bahasa dan Sastra Indonesia FKIP Universitas Jambi
Authors: Purba Andiopenta
Published: May 2023

Jambi Malay is rich in expressions that can be used as teaching materials in the development of local content curriculum in the field of culture. Things related to this expression include; (1) the form of expression in Jambi Malay can be in the form of phrases, clauses, and sentences. (2) the meaning contained in Jambi Malay expressions can be in the form of grammatical, connotative and implied meanings, and (3) the use of Jambi Malay expressions is as satire, suggestion, advice, and as a rule norm that must be obeyed and implemented. This expression is always used as a prologue when speaking in the realm of family, custom, government and state ceremonies. All of these expressions were developed into teaching materials in the development of local content curricula in formal schools in Jambi province. In determining local content subjects, there are several steps that can be taken, including; (1) identify regional conditions and needs; (2) determine the function and composition or composition of local content; (3) determining local content study materials; (4) determining local content materials; and (5) develop competency standards and basic competencies and learning syllabus. These five steps will of course be based on the form, meaning, and function of the various prologue expressions of Jambi Malay.
Chapter 12a: TBE-epidemiology by country – an overview
Authors: Erber Wilhelm , Schmitt Heinz-Josef , Janković Tamara Vuković
Published: May 2023

TBE is a flavivirus infection of the central nervous system (CNS), transmitted by ticks and in some instances by ingestion of unpasteurized milk. It is diagnosed in the forested belts of Northern Eurasia ranging from the UK, eastern France, The Netherlands and Norway down to Italy through central and Eastern Europe, Russia, Kazakhstan, and China to Japan. About 10,000 cases of TBE are reported annually, likely a significant underestimate as serological testing is more sporadic than complete and, in some countries, (like Japan) not even available. The European Centre for Disease Prevention and Control (ECDC) have put TBE on their list of notifiable diseases. Their case definition requires clinical symptoms of CNS infection plus virological or serological confirmation of the infection, usually by detection of specific immunoglobulins IgG and IgM. Vaccination against TBE is on the World Health Organization’s List of Essential Medicines. the safest and most effective medicines needed in a health system. Surveillance of TBE and the TBEV is incomplete. Reported incidences do not reflect actual risk since this fluctuates annually as a result of changes in exposure, vaccine uptake, intensity of case finding and reporting, climate factors, reservoir animals and ticks – just to mention the most relevant factors. For largely unknown reasons (including human behavior, improved diagnostics, or climate change) TBEV appears to be spreading north, east, west, even south and to higher altitudes to areas that were previously believed to be free of the virus.
TBE in Finland
Authors: Jääskeläinen Anu , Åhman Heidi
Published: May 2023

Finland is at the northernmost edge of the TBE endemic area in Europe. Here TBE is focally endemic. An aseptic encephalitis disease has been known in Kumlinge Island in Åland Islands since the 1940s. TBE is also known in Finland by name Kumlinge disease.
TBE in Latvia
Authors: Zavadska Dace , Freimane Zane
Published: May 2023

Aggregated data on TBE cases in Latvia are available from 1955, but serological testing for TBE began in the 1970s. Since TBE became notifiable in Latvia, epidemiological changes of disease incidence have been dramatic. Between 1990–2000 Latvia had the highest rates of TBE incidence in the world, ranging from 8 to 53 cases per 100,000 population. Although the incidence decreased significantly in the past 10 years to about half – from 14.58/100,000 in 2010 to 7.86/100,000 in 2018 – Latvia still ranks very high among all countries in Europe with an annual incidence of 12.67/100,000 in 2022. The distribution of TBE cases in Latvia varies between different regions with the highest incidence usually registered near the northwestern coast.
TBE in Norway
Authors: Paulsen Katrine M. , Vikse Rose , Soleng Arnulf , Edgar Kristin , Lindstedt Heidi Elisabeth Heggen , Dorenberg Dagny H. , Wiklund Berit Sofie , Andreassen Åshild
Published: May 2023

In Norway, tick-borne encephalitis (TBE) has been a mandatory notifiable disease since 1975 (Norwegian Surveillance system for communicable diseases, MSIS). According to ECDCs classification, coastal areas in southern Norway (counties of Agder, and Vestfold and Telemark) are endemic for TBE. Further, Viken County (former Østfold, Akershus and Buskerud), and western and northern Norway to Brønnøy municipality is imperiled.
TBE in Poland
Authors: Pancer Katarzyna , Gut Włodzimierz
Published: May 2023

Clinical symptoms of tick-borne encephalitis (TBE) were first described in Poland in 1948 by Demiaszkiewicz. All patients had been living in the Białowieża region (in northeastern Poland). Similar infections were described to those that had been diagnosed in the same region before World War II as complicated cases of typhoid fever or influenza.
TBE in China
Authors: Junfeng Yang , Schmitt Heinz-Josef
Published: May 2023

The first TBE patients in China were reported in 1943, and the TBEV was isolated from the brain tissues of 2 patients in 1944 by Japanese military scientists, and from patients and ticks (Ixodes persulcatus and Haemaphysalis concinna) in 1952 by Chinese researchers. The Far Eastern viral subtype (TBEV-FE) is the endemic subtype that has been isolated from all 3 known natural foci (northeastern China, western China, and southwestern China). Recently a new “Himalayan subtype” of the TBEV (TBEV-HIM) was isolated from wild rodent Marmoata himalayana in the Qinghai-Tibet Plateau. The main vector of the TBEV in China is I. persulcatus. One recent report suggests that the TBEV-SIB is prevalent in the Uygur region (North West China) but epidemiological modelling indicates that the TBEV may occur even widely all over China (Figure 3). Likely, the disease is often missed by clinicians due to a lack of the availability of specific diagnostic assays.
TBE in the Czech Republic
Authors: Pazdiora Petr
Published: May 2023

The TBE virus (TBEV) was first isolated in the Czech Republic by Czech scientists in 1948-1949 from both a patient and also from Ixodes ricinus ticks. However, even before 1948, etiologically unclear summer cases of viral meningoencephalitis had been reported, and likely, at least in part, they are attributable to the TBE virus. These cases were reported mostly from patients in the districts of Beroun (Central Bohemia), Hradec Králové (East Bohemia), Vyškov (South Moravia), and occasionally from the neighborhood of Prague. The official reports of these probable cases of ”tick-borne encephalitis” were registered in the database of the National Institute of Public Health in Prague since 1945.
Hepatocellularis carcinomás beteg sikeres májátültetése TACE- és sorafenibkezeléssel elért tumorméret-csökkentés után. Társszakmák sikeres együttmûködése
Authors: András Csilla , Árokszállási Anita , Csiki Emese , Matolay Orsolya , Árkosy Péter , Jancsik Viktor , Nemes Balázs , Tóth Judit , Varga Enikô
Published: May 2023

Egy hosszan túlélô primer májrákos nôbeteg tanulságos esetét mutatjuk be. Ap pen - dectomia során transzfúziót kapott, 9 év múlva derült ki hepatitis C-vírus- (HCV-) po zitivitása. Az antivirális kezelés akkor sikertelen volt, májcirrhosis alakult ki. A fel tételezett HCV-infekciót követôen, 24 év vel késôbb hepatocellularis carcinomát állapítottak meg a májban szoliter tumor formájában. Két ciklus transzarteriális kemoembolizáció (transarterial chemoembolization, TACE) után exploratív laparatomiára került sor, azonban a tumoros májhilusi infiltráció miatt a folyamat sebészileg irreszekábilisnak bizonyult. Ezt figyelembe véve a multidiszciplináris onkoteam sorafenibkezelést javasolt. A beteg 2,5 évig kapta a sorafenibet, amit jól tolerált, a tumor megkisebbedett. Ezután még egy alkalommal történt TACE-kezelés. A beteg ezt követôen alkalmassá vált a májtranszplantációra. Az alkalmazott bridging terápiával, két sikertelen donorriasztás után a májátültetés sikeresen megtörtént. A hosszú túlélést végül a cirrhosist és a HCC problémát is megoldó májátültetés biztosította. Az újabb direkt ható antivirális gyógyszerek hatására a beteg tartósan HCV-negatív lett, és jelenleg csak hepatológiai gondozás alatt áll. Az eset példa arra, hogy inoperábilis hepatocellularis májrák (HCC) esetén lehetséges a tumor megkisebbítése és a májátültetés. Hangsúlyozzuk, hogy a HCC-ben szen - vedô betegek ellátásában fontos a társ szak - mák együttmûködése. Lényeges, hogy olyan intézetekbe irányítsák a beteget, ahol a potenciálisan szóba jövô kezelések teljes skálája elérhetô, valamint az alap májbetegség követése, ellátása is megtörténik.
Thinking and Writing Together: Institutional Pedagogy and Félix Guattari
Authors: Thornton Edward
Published: May 2023

Institutional pedagogy is a radical educational practice that began in France in the first half of the twentieth century. It aims to transform the material context of learning in order to empower students to collectively take responsibility for their own lives. As an analysis of the effects of this practice on the work of Félix Guattari, the purpose of this article is twofold. First, it aims to describe the theoretical and practical cross-pollination that occurred between the two movements of institutional pedagogy and institutional psychotherapy. Second, it argues for a new methodology for reading the published works of Félix Guattari in the context of institutional pedagogy. The article begins with a brief analysis of the work of Celéstin Freinet, followed by an account of the development of his techniques by Aïda Vasquez, Fernand Oury, Jean Oury and Guattari. After showing how these practices informed Guattari’s work as a political activist, in the final section I argue that we should treat the figure of Félix Guattari as a special kind of ‘writing machine’.
KEBIJAKAN PENYALURAN PEKERJA MIGRAN MASA PANDEMI COVID -19 DI KABUPATEN PONOROGO
Authors: Rahayu Nirma Vinny , DJ Ekapti Wahjuni , Kusuma D Dian Suluh , Triono Bambang
Published: May 2023

Abstrak

Indonesia mengalami pandemi selama tiga tahun terakhir yang sangat luar biasa telah menyebabkan tersebarnya Pekerja Migran Indonesia (PMI) ke luar negeri. Dengan berakhirnya penyaluran PMI selama merebaknya pandemi Covid-19 di Indonesia, menyebabkan munculnya berbagai kebijakan Dinas Tenaga Kerja (Disnaker) dan penyaluran PMI di PT. Tulus Widodo Putra dan PT Andhika Putra Mandiri di masa pandemi. Tujuan dari penelitian ini adalah untuk mengetahui kebijakan Kementerian Tenaga Kerja dan menganalisis penyaluran tenaga kerja Indonesia di PT. Tulus Widodo Putra dan PT. Andhika Putra Mandiri. Metode penelitian menggunakan deskripsi eksplanatif dengan pendekatan kualitatif. Teknik penentuan informan menggunakan teknik purposive sampling. Hasil penelitian menunjukkan bahwa kebijakan dibuat dengan tujuan menghentikan penyaluran Pekerja Migran ke luar negeri yang membawa dampak sangat signifikan bagi PT.Tulus Widodo Putra dan PT. Andhika Putra Mandiri serta semua calon Pekerja Migran yang terdapat pada kedua PT tersebut. Hasil penelitian di lapangan menunjukkan bahwa selama pandemi Covid-19, pengoperasian diberhentikan dan semua tempat penampungan dikosongkan untuk mencegah terjadinya penularan virus Covid-19 yang tidak sengaja, akan tetapi salah satu perusahaan tersebut tidak mengikuti insturksi dari Dinas Tenaga Kerja Kabupaten Ponorogo.

Kata Kunci: Pandemi Covid – 19, Kebijakan, Penyaluran PMI
EVALUATION OF THE KARTU TANI PROGRAM IN SUBSIDIZED FERTILIZERS DISTRIBUTION IN BANYUMAS REGENCY, CENTRAL JAVA PROVINCE
Authors: Ramadhoni Imwadia , Nomita Berliana Prilli
Published: May 2023

Abstract

The Governor of Central Java Province initiated the Kartu Tani Program to realize the distribution, control, and supervision of subsidized fertilizers for farmers. However, there are still problems with implementing this program from the farmers, KPL (Complete Fertilizer Kiosk) and distributors, related agencies, and third parties, BRI Bank. The problems include the scarcity of subsidized fertilizers, delays in fertilizer distribution, inaccuracy targeting, and overpriced provision. So, this article proposes to discuss the Kartu Tani Program evaluation in Banyumas Regency. Using the Quasi Qualitative Design (QQD), the data was obtained from various documents, observations, and interviews. This article also used Manual Data Analysis Procedure (MDAP). Based on the evaluation, after the existence of the Kartu Tani, farmers experienced many conveniences, including the relatively low price of fertilizer, the fertilizer quota, and the specific location of the fertilizer seller based on residents and farmer groups. Not only farmers, fertilizer sellers, and distributors also benefit from the Kartu Tani to make subsidized fertilizer reports from sales to distributors. On the other side, we show that many complaints regarding the Kartu Tani are still entered into the Banyumas Regency complaint hotline, but most of these complaints can be resolved. The Department of Agriculture and Food Security of Banyumas Regency commits to optimally implementing the Kartu Tani Program as the right solution for subsidized fertilizers distribution to farmers in the Banyumas Regency.

 

Keywords: Fertilizer distribution, Kartu Tani, policy evaluation, subsidized fertilizers.
Türkiye’deki sosyal girişimcilik faaliyetlerinin sosyal gelişme endeksi bağlamında içerik analizi ile incelenmesi
Authors: ESEN Dilek
Published: May 2023

Bu araştırmada, Türkiye’deki sosyal girişimcilik faaliyetlerinin, Sosyal Gelişme Endeksi’nin hangi boyutları üzerinde yoğunlaştığının tespit edilerek, bu yoğunlaşmanın gerekçelerin tartışılarak mevcut uygulamalara ve geleceğe projeksiyon tutulması amaçlanmıştır. Araştırmanın evrenini 2022 yılında Türkiye’de faaliyet gösteren sosyal girişimler oluşturmaktadır. Araştırma örneklemi, Ashoka Türkiye Fellow’ları, British Council Türkiye (2019) raporu, Türkiye Üçüncü Sektör Vakfı internet sitesi, akademik çalışmalar vb. aracılığıyla bilgilerine ulaşılan 163 sosyal girişimden oluşmaktadır. Verilerin analiz edilmesi için Maxqda Programı kullanılmıştır. Araştırmada kullanılacak temaların ve kodların tespit edilmesinde Sosyal Gelişme Endeksi ve Sürdürülebilir Kalkınma Hedefleri kullanılmıştır. Araştırmanın güvenilirliğini test etmek amacıyla Kappa Katsayısı hesaplanmış ve araştırmanın güvenilir olduğu tespit edilmiştir. Araştırmadan elde edilen bilgilere göre, Sosyal Gelişme Endeksi bağlamında sosyal girişimlerin faaliyetlerinin en fazla yoğunlaştığı kategorinin, “Refahın Temel Bileşenleri” kategorisi olduğu tespit edilmiştir. Bu kategori altında, sosyal girişimlerin eğitimle ilgili alanlarda faaliyetlerinin yoğunlaştığı tespit edilmiştir. Sosyal gelişmeyi desteklemesi açısından “Çevre Kalitesi” ile ilgili sosyal girişimcilik faaliyetlerinin artmasına ihtiyaç olduğu sonucuna ulaşılmıştır. Ayrıca ülkemizde kişisel haklar, özgürlükler, kapsayıcılık gibi konuları kapsayan “Fırsat” kategorisiyle ilgili sosyal girişimcilik çalışmaları olmasına rağmen, sosyal gelişme için “Fırsat” kategorisiyle ilgili daha fazla sosyal girişim faaliyetine ihtiyaç olduğu tespit edilmiştir.
Hayvancılık İşletmelerinde Teknoloji Kullanımı ve Ekonomik Verimlilik
Authors: GEZİCİ Mustafa , ÜNAY Engin , ÜSTÜN Kerim , COŞKUN Muhammed İkbal
Published: May 2023

Artan Dünya nüfusunun beslenmesi için dengeli ve sürdürülebilir gıdaya erişiminin sağlanması konusunda bilim insanları, üreticiler, tedarikçiler ve piyasalara yön veren politika yapıcıları zaman ve bütçe harcamaktadır. Küresel insan nüfusunun 2050 yılına kadar 9 milyara ulaşacağı tahmin edilmektedir (Alexandratos ve Bruinsma, 2012). Birleşmiş Milletler Gıda ve Tarım Örgütü (FAO) nun 2009 raporuna göre, artan insan nüfusuna ayak uydurabilmek için küresel gıda üretiminin %70 oranında artması gerektiğini belirtmiştir. Benzer şekilde, et ve diğer hayvansal gıda ürünlerine yönelik küresel talep giderek artmaktadır. Ayrıca, gelişmekte olan ülkelerdeki ekonomik koşullar iyileştikçe, gıda tercihinde hayvansal proteine doğru kayma ve talebin daha da artması beklenmektedir (Thompson, 2015). Ölçek ekonomileri, çiftçileri faaliyetlerini genişletmeye ve büyütmeye zorlayarak daha yüksek çıktı sağlar. Sonuç olarak, daha az sayıda çiftçi tarafından işlenen, daha fazla sayıda hayvanın bakıldığı çiftliklerin ortaya çıkması beklenmektedir. Ayrıca, özellikle sanayileşmiş ülkelerde çiftçilerin ortalama yaşı artmaktadır (ABD ve Avrupa'da ortalama 58, Japonya'da 63) (Morrone vd., 2022). Bu faktörler göz önüne alındığında (artan çiftlik ölçeği ve yetiştirilen hayvan sayısı), çiftçilerin geçmişte bel bağladıkları gözlem kapasitesi ve uygulamalı deneyim artık etkin günlük sürü yönetimi sağlamak için yeterli değildir (Frost vd., 2003; Parsons vd., 2007).
Farklı geometrik oluklu çekirdeğe sahip ahşap esaslı kompozit panellerin vida tutma dirençlerinin belirlenmesi
Authors: KAYA Musa , İMİRZİ H.özgür
Published: May 2023

Yapılan çalışmada geometrik oluklu çekirdeğe sahip ahşap esaslı kompozit panellerin yoğunluk değerleri ve levha yüzeyinden vida tutma dirençleri belirlenmiştir. Bu amaçla panellerin çekirdek geometrilerine üç farklı geometrik oluk (Dairesel, dikdörtgen ve trapez) şekli işlenerek elde edilen çekirdek katmanlarının alt ve üst yüzeylerinde 4’er mm’lik kontrplak ve liflevha kullanılarak, üre formaldehit tutkalı ile yapıştırılmıştır. Üretilen panellerin yoğunluk değerleri ve vida tutma dirençlerini belirlemek için ilgili standartlarda belirtilen esaslar doğrultusunda deneyler yapılarak veriler elde edilmiştir. Elde edilen verilerin çoklu varyans analizleri yapılarak anlamlı çıkan faktörlerin grupları arasındaki farklılıkların tespit edilmesi için Duncan testi yapılmıştır. Yapılan testlerin sonuçlarına göre ahşap esaslı kompozit panellerin çekirdek katmanına işlenen farklı geometrik oluklu şekillerin; panellerin vida tutma direnci ve yoğunluk değerlerinde azalmalara sebep olduğu görülmüştür. Deney sonuçlarına göre en yüksek vida tutma direnci; kontrplak yüzeyli dikdörtgen oluklu çekirdeğe sahip panelde 15.36 N/mm² iken en düşük vida tutma direnci ise kontrplak yüzeyli dairesel oluklu çekirdeğe sahip panelde 8.92 N/mm² olduğu tespit edilmiştir.
Effect of Transformational Leadership, Servant Leadership, and Spiritual Leadership on Organizational Citizenship Behavior
Authors: Subhaktiyasa Putu Gede , Andriana Kiki Rizki Fista , Sintari Silvia Ni Nyoman , Wati Wayan Shinta , Sumaryani N Putri , Lede Yohanes Umbu
Published: May 2023

Purpose - Universities are unique institutions that require different leadership styles to achieve their goals. Therefore, this research examines the effect of transformational, servant, and spiritual leadership on the Organizational Citizenship Behavior (OCB) of lecturers. 
Methodology - The research adopted a quantitative approach, using a questionnaire with a Likert scale to collect data. Purposive sampling was utilized to obtain 120 participants. The SEM-PLS analysis was employed to test the research hypothesis.   
Findings - The results showed that transformational leadership did not have a significant impact on OCB. Meanwhile, both servant and spiritual leadership had a positive effect on OCB. Among the three leadership styles, spiritual leadership was effective in universities, specifically in developing organizational behavior.
Originality - Previous research on leadership in educational institutions only focuses on one or a few leadership styles. The current research is unique because it examines the influence of three leadership styles on OCB in universities. The variables in the proposed model are new constructs that necessitate further investigation in order to gain a better understanding of their relationship with OCB.
A obra para dois pianos de Francisco Mignone e Justaposição Funcional
Authors: Castelan Póvoas Maria Bernardete , Dietrich Alexandre
Published: May 2023

Entre o vasto trabalho musical de Francisco Mignone, há setenta e quatro peças para a formação instrumental a dois pianos. Como piano I, integram esta coleção não somente composições suas, mas peças solo de outros compositores como Ernesto Nazareth, Zequinha de Abreu, Waldemar Henrique, Lorenzo Fernandez. Na elaboração do repertório por Mignone identifica-se a Justaposição Funcional, estratégia de composição configurada pela sobreposição expressiva de peças independentes: os dois pianos executam peças originais que dialogam e combinam, e podem ser interpretadas como peças solo. Tal procedimento confere ambiguidade funcional às peças, oferecendo possibilidades de interpretação de maneira individual às partes compostas originalmente por Mignone e, quando justapostas, de serem interpretadas simultaneamente, em Duo. O objetivo com este artigo foi revelar como Mignone manipulou parte dessa obra e argumentos que ilustram a compreensão de justaposição enquanto estratégia composicional e de interpretação do repertório em foco.
β-caryophyllene as an attractant for the cacao mirid bug, Helopeltis bakeri Poppius (Hemiptera: Miridae), and chemodiversity of its host plant volatiles
Authors: Tavera Mary Angelique A. , Dela Cruz Maria Criselda V. , Santos Kris Lord T. , Amalin Divina M. , Janairo Jose Isagani B.
Published: May 2023

The cacao mirid bug, Helopeltis bakeri, is a major insect pest of cacao in the Philippines. It feeds on pods causing puncture wounds that become necrotic lesions and may lead eventually to pod abortion. There is currently no semiochemical-based system developed for the monitoring and control of H. bakeri. Here, we report a kairomone identified from host plants of H. bakeri as a potential attractant. Volatile components were extracted using solid-phase microextraction (100-µm polydimethylsiloxane) and analyzed by gas chromatography - mass spectrometry. Chemodiversity analysis considering compound richness, evenness, and disparity showed similar phytochemical diversity among the six host plants, suggesting that chemodiversity is a factor in the host selection behavior of H. bakeri. Comparison of volatiles revealed that β-caryophyllene was present in all host plants. Using a wind tunnel, an impregnated lure containing 90 µg β-caryophyllene showed the highest attraction to adult H. bakeri. The results show the potential of β-caryophyllene as attractant that can be used in the development of kairomone-based trapping systems for H. bakeri as part of a holistic integrated pest management system for cacao.
Contribution of traditional deep fermentation to volatile metabolites and odor characteristics of Wuyi rock tea
Authors: Jia Xiaoli , Wang Yuhua , Li Qisong , Zhang Qi , Zhang Ying , Lin Shaoxiong , Cheng Pengyuan , Chen Meihui , Du Mengru , Ye Jianghua , Wang Haibin
Published: May 2023

Fermentation is extremely important for the formation of the special flavor of Wuyi rock tea. This study determined volatile metabolite contents using GC-MS technique and futher analyzed their odor characteristics during the traditional deep fermentation technology of Wuyi rock tea. The results showed that 17 characteristic compounds significantly changed during the first stage of the preliminary processing, namely fresh leaves, withering and fermentation. The key to the formation of floral aroma lied in dihydromyrcenol, and the woody aroma derived from six terpenoids, and their synthesis depended on dihydromyrcenol content. The fruity aroma was dominated by six esters, and the fruity aroma mainly came from (Z) -3-hexen-1-yl butyrate, (E) -3-hexen-1-yl butyrate and 5-Hexenyl butyrate. This study provided an important theoretical and practical basis for improving the preliminary processing of Wuyi rock tea.
Digital identity performance through emoji on the social media platform Instagram
Authors: Marko Karoline
Published: May 2023

Introduction

Emoji are omnipresent features of digital discourses and have become almost inherent features of online interactions. Given the large and ever-increasing variety of emoji, it is not farfetched to assume that users will have preferences for particular emoji or emoji combinations, and that their preferences are indexically related to their identities, for example in terms of skin-tone and/or gender. With a case study, the present paper aims to address a particular gap in the extant literature, namely the role of emoji in the presentation of different identities of one individual, namely a US American female in her early 20s.

Methods

The data for this study was drawn from Instagram and comprises a total of 625 posts made by one user to three of her own accounts with the platform. Each account represents a different aspect of her identity, and the analysis demonstrates that while the use of some emoji remains stable across all of her accounts, other emoji are very account-specific in that they are employed to highlight one particular aspect of her identity.

Results

The results thus indicate the different values that emoji might have in the contexts of authorship analyses. Additional studies are required to investigate this phenomenon further.
Conduction system pacing improves the outcomes on patients with high percentage of ventricular pacing and heart failure with mildly reduced ejection fraction
Authors: Zhang Duo-duo , Zhao Fu-lu , Yang Yi-heng , Ma Cheng-ming , Ma Pei-pei , Zhao Yan-ni , Xia Yun-long , Gao Lian-jun , Dong Ying-xue
Published: May 2023

Aims

This study aimed to investigate the efficacy and safety of CSP in patients with a high percentage of ventricular pacing and heart failure with HFmrEF.

Methods

Patients who underwent CSP for HFmrEF and ventricular pacing >40% were consecutively enrolled from January 2018 to May 2021. All participants were followed up at least 12 months. Clinical data including cardiac performance and lead outcomes were compared before and after the procedure. Left ventricular ejection fraction (LVEF) was measured using the biplane Simpson's method. HFmrEF was defined as heart failure with the LVEF ranging from 41%–49%.

Results

CSP was successfully performed in 64 cases (96.97%), which included 16 cases of left bundle branch pacing (LBBP) and 48 cases of His bundle pacing (HBP). After a mean of 23.12 ± 8.17 months follow-up, NYHA classification (P < 0.001), LVEF (42.45 ± 1.84% vs. 49.97 ± 3.57%, P < 0.001) and left ventricular end diastolic diameter (LVEDD) (55.59 ± 6.17 mm vs. 51.66 ± 3.48 mm, P < 0.001) improved significantly. During follow-up, more than half (39/64,60.9%) of patients returned to normal LVEF and LVEDD with complete reverse remodeling. The pacing threshold in LBBP was lower (0.90 ± 0.27 V@0.4 ms vs. 1.61 ± 0.71 V@0.4 ms, P < 0.001) than that in HBP. No perforation, electrode dislodging, thrombosis or infection was observed during follow-up.

Conclusions

CSP could improve the clinical outcomes in patients with HFmrEF and a high percentage of ventricular pacing. LBBP might be a better choice because of its feasibility and safety, especially in patients with infranodal atrioventricular block.
Sex-specific differences in primary Sjögren's disease
Authors: Punnanitinont Achamaporn , Kramer Jill M.
Published: May 2023

Many autoimmune diseases show a striking female sex predilection, including primary Sjögren's disease (pSD). Patients with pSD display exocrine gland pathology, such as salivary hypofunction and salivary and lacrimal gland inflammation. Moreover, many serious systemic disease manifestations are well-documented, including interstitial nephritis, hypergammaglobulinemia and neuropathies. Of note, women and men with pSD display distinct clinical phenotypes. While the underlying reasons for these clinical observations were poorly understood for many years, recent studies provide mechanistic insights into the specific regulatory landscapes that mediate female susceptibility to autoimmunity. We will review factors that contribute to the female sex bias, with an emphasis on those that are most relevant to pSD pathogenesis. Specifically, we will focus on sex hormones in disease, genetic alterations that likely contribute to the significant disease prevalence in females, and studies that provide evidence for the role of the gut microbiota in disease. Lastly, we will discuss therapeutics that are in clinical trials for pSD that may be particularly efficacious in targeting signaling networks that mediate inflammation in a sex-specific manner.
Impacts of model resolution on responses of western North Pacific tropical cyclones to ENSO in the HighResMIP-PRIMAVERA ensemble
Authors: Liu Jingchan , Yuan Chaoxia , Luo Jing-Jia
Published: May 2023

The El Niño/Southern Oscillation (ENSO) is the major driver of interannual variations of the western North Pacific (WNP) tropical cyclones (TCs). Realistic reproduction of ENSO-WNPTC teleconnection in coupled models (CGCMs) is thus crucial for improved seasonal-to-interannual prediction of WNPTC activity. Here, basing on the outputs of six pairs of high-resolution (HR) and low-resolution (LR) CGCMs participating the HighResMIP-PRIMAVERA project, we showed that the HR models outperform the LR ones in reproducing the observed increase of TC genesis in the southeastern WNP but the decrease in the northwestern WNP in the developing years of El Niño. The better performance of HR than LR models is on one hand due to the generally increased frequency and variability of TCs in the HR models. On the other hand, the teleconnection of El Niño to the WNP shows a dipole circulation difference between the HR and LR models with an anomalous cyclone in the southeastern WNP and anticyclone in the northwestern WNP, which enhances the dipole TC genesis anomalies in the HR compared to the LR models. The teleconnection difference stems from the westward shift of the ENSO-related SST and convection anomalies in the tropical Pacific in the HR compared to the LR models, which may be ultimately linked to the reduced cold tongue biases in the HR models.
Alternative mechanisms of managing the education’s development in the social investment model of Russia’s economic growth: standardization versus deregulation
Authors: Dianova Valentina Yu , Krasilnikova Varvara G. , Kelina Kirena G. , Nazarenko Anton V.
Published: May 2023

Regression analysis is used to determine the contribution of the factors of managing the development of higher education – share of university branches – to increase the population’s quality of life. To determine the optimal approach to managing education’s development in the social investment model of Russia’s economic growth with alternative mechanisms of standardization and deregulation. The results of the research show that absolute standardization, as well as absolute deregulation of higher education, does not allow achieving significant results in the sphere of increase in quality of life in Russia. The determined and substantiated optimal scenario of managing the development of higher education in Russia to increase the quality of life envisages a foundation on a flexible approach, which envisages the combination of standardization and deregulation. It is recommended to entirely refuse branches in favor of main universities, refuse government financing in favor of fee-based education and refuse diversification of education forms in favor of the intramural form of study. This allows raising the quality of life by 13.26% (up to 70.87 points). For practical implementation of this approach, it is offered to allow each region to form their own programs of development of higher education with the foundation of the main federal principles.
Effects of TCM on polycystic ovary syndrome and its cellular endocrine mechanism
Authors: Chen Huize , Deng Chujun , Meng Zeyu , Meng Shengxi
Published: May 2023

Polycystic ovary syndrome (PCOS) is a reproductive endocrine disease characterized by menstrual disorders, infertility, and obesity, often accompanied by insulin resistance and metabolic disorders. The pathogenesis of PCOS is relatively complex and has a certain relationship with endocrine disorders. The increase of androgen and luteinizing hormone (LH) is the main cause of a series of symptoms. Traditional Chinese medicine (TCM) has obvious advantages and significant curative effects in the treatment of this disease. It can effectively reduce the insulin level of PCOS patients, regulate lipid metabolism, and increase ovulation rate and pregnancy rate and has fewer side effects. This article reviews the efficacy and safety of Chinese herbs and other TCM (such as acupuncture) in the treatment of PCOS and its complications in recent years, as well as the effect and mechanism on cellular endocrine, in order to provide a new clinical idea for the treatment of PCOS.
Multiple game trading strategy of multiple virtual power plants considering carbon trading
Authors: Chu Tianfeng , An Xingchen , Zhu Yu , Wang Xueying , Deng Limin
Published: May 2023

The large-scale access of distributed energy resources has a certain impact on the power grid, so distributed energy resources cannot participate in the power market transactions alone. The concept of the virtual power plant (VPP) has thus emerged, which can aggregate distributed power sources and controllable loads in a region for coordinated regulation. The trading of VPPs should not only consider the economy but also its degree of low carbon. Therefore, this paper constructs a unified bidding strategy for multi-VPPs that considers carbon–electricity integration trading. We design a multi-game trading strategy among multi-VPPs to achieve unified trading, after each VPP determines its internal trading strategy. Finally, through simulation, we verify that the multiple game strategy between multi-VPPs that considers carbon trading here proposed can effectively improve the efficiency and trading income of VPPs and promote the consumption of new energy.
The relationship between vegetation and soil moisture reveals the vegetation carrying capacity threshold—A case study of a Haloxylon ammodendron plantation in the Alxa desert, China
Authors: Zhou Dongmeng , Si Jianhua , He Xiaohui , Jia Bing , Zhao Chunyan , Wang Chunlin , Qin Jie , Zhu Xinglin , Liu Zijin
Published: May 2023

Afforestation is an important and effective way to curb wind-sand hazards in the Alxa Desert. However, over-afforestation makes soil drying occur frequently. The formation of a soil drying layer is seriously restricting the effectiveness of vegetation construction and regional ecological stability. To clarify the process of soil desiccation inHaloxylon ammodendronplantations and determine the suitable planting years, a typicalH. ammodendronplantation in this area was selected as the research object, and the soil moisture variation characteristics of this sand-fixing vegetation region with vegetation age were analyzed. The analysis results on soil water supply, consumption, and balance showed that the soil water storage in 0–400 cm soil layer ofH. ammodendronplantation varies significantly in different ages. The soil water storage in 0–11 years old was the largest, and the soil water supply was greater than the soil water consumption. The soil water storage in profile increased with the increase of precipitation, the soil water storage ofH. ammodendronat 11–22 years old increased first and then decreased with precipitation, and the inflexion existed in 16.5 years old. The soil water consumption ofH. ammodendronplantation at 22–46 years old was greater than that of soil water supplement, and the soil moisture appeared negative balance continuously. Therefore, to prevent further deterioration of soil moisture ecological environment in theH. ammodendronplantation and to promote the sustainable development of afforestation in desert areas, thinning measures are suggested when the growth period reaches 16.5 years. The research results could provide scientific basis for afforestation and soil dry layer regulation in the Alxa desert.
Impacts of environmental policy uncertainty on urban environmental pollutant emissions in China: a study based on textual analysis
Authors: Li Rongda , He Jing
Published: May 2023

Studies mainly focuses on measuring the economic policy uncertainty in different countries. However, few studies have focused on the construction of the environmental policy uncertainty index (EPUI). This paper selects 460 newspapers from the China National Knowledge Infrastructure (CNKI) newspaper database from 2001 to 2016, and uses the text analysis method to directly construct the national, provincial, and prefecture-level EPUI of China. We have analyzed the distribution and fluctuation trend of the EPUI, and use two-way fixed effect model with panel data to investigate the impact of environmental policy uncertainty on environmental pollutant emissions at the city level. An important discovery has been made through our research, indicating that the rise in environmental policy uncertainty is likely to result in a reduction of pollutant emissions such as urban industrial sulfur dioxide and carbon dioxide. However, this reduction comes at a cost to the promotion of the development of urban secondary industry. The Chinese EPUI constructed for the first time in this article provides significant basic data for research in the environment and energy fields, and also provides important empirical evidence for achieving China’s carbon peak and carbon neutrality goals.
Identification of genetic alterations in couples and their products of conceptions from recurrent pregnancy loss in North Indian population
Authors: Srivastava Priyanka , Bamba Chitra , Chopra Seema , Rohilla Minakshi , Chaudhry Chakshu , Kaur Anupriya , Panigrahi Inusha , Mandal Kausik
Published: May 2023

Background: Recurrent pregnancy loss (RPL) is one of the most common pregnancy-related complications, which can be stressful and emotionally draining for a couple. Genetic alterations, which are responsible for RPL, can be present in either of the three genomes: mother, father, or their fetuses. In addition, environmental factors interacting with these three genomes can affect germline cells. With this aim, the present study was conducted to understand the underlying etiology of RPL using Next-generation sequencing (NGS; couple exome and TRIO exomes) in combination with cytogenetic tests [karyotyping and chromosomal microarray (CMA)].

Material & Methods: In present study we recruited 61 couples with RPL (history of ≥ 2 abortions) and 31 products of conceptions (POCs). For all couples karyotyping was done at the time of recruitment, followed by collection of POC samples and parental blood samples. Before processing POC samples for CMA, they were checked for maternal cell contamination (MCC) by QF-PCR. In POC samples with no pathogenic variant, TRIO exome sequencing was done. Further, in case of unavailability of POC sample, couple exome sequencing was done for RPL couples.

Results: In six individuals out of 61 couples (5%), abnormality in karyotypes was detected. Among 116 normal karyotypes, there were 11 heteromorphisms (9.5%), for which the couples had to be counselled and reassured. Out of the 31 POCs, 10 were excluded because of MCC (around 30%) and one had major aneuploidy. CMA in POCs identified pathogenic copy number variations (CNVs) in 25% of cases (5/20) and variant of unknown significance (VUS) in 20% of cases (4/20). Autosomal trisomy was the most frequent chromosomal abnormality diagnosed. NGS was performed to establish single-gene causes of RPL. Couple exome sequencing was performed in 20 couples, and 14 were found to be carriers for autosomal recessive conditions. A total of 50 potential disease-causing variants in 40 genes were identified in 33 of 40 individuals (82.5%). Putative causative variants were identified in 37.5% of the TRIO cases (3/8). Mutations in few important genes (SRP54, ERBB4, NEB, ALMS, ALAD, MTHFR, F5, and APOE), which are involved in vital pathways, early embryonic development, and fetal demise, were identified in the POCs.

Conclusion: It enhances our understanding of prenatal phenotypes of many Mendelian disorders. These mutated genes may play an auxiliary role in the development of treatment strategies for RPL. There was no correlation of the number of abortions with etiological yield of any technique to detect the cause of RPL. This study shows the utilization of combination of techniques in improving our understanding of the cause of early embryonic lethality in humans.
Women's experiences with implementation of the physiologic birth program in Iran: a qualitative content analysis study
Authors: Moridi Azam , Abedi Parvin , Iravani Mina , Khosravi Shahla , Alianmoghaddam Narges , Maraghi Elham , Saadati Najmieh
Published: May 2023

Introduction

Increased rate of caesarean section (CS) without medical indication is a global concern. According to the guidelines of the World Health Organization (WHO), the physiologic birth program is one of the strategies for reducing the rate of unnecessary caesarean sections. The aim of this study is to explain women's experiences with the implementation of the physiologic birth program in Iran.

Materials and methods

This study is a part of a mixed-method study involving 15 targeted semi-structured interviews individually conducted with women attending physiologic birth classes between January 2022 and June 2022. Interviews continued until data saturation was achieved. Data were analyzed using conventional content analysis approach based on the criteria proposed by Graneheim and Lundman, using MAXQDA10 software.

Results

Analysis of the findings of the study led to the emergence of 2 themes, 4 categories, and 10 subcategories. The first theme was the positive experiences of the women (“satisfaction with pregnancy” and “making the childbirth process pleasant”), and the second theme was their negative experiences with physiologic birth (“challenges and limitation of physiologic birth program” and “lack of high-quality obstetric services in the public health system”).

Conclusion

The results of this study showed that childbirth preparation classes reduced women's fear and stress and enhanced their positive attitude toward vaginal delivery by preparing them for childbirth. Also, effective communication with midwives and their support along with efficient implementation of physiologic birth techniques led to successful pain management and satisfaction with the birth process. Policymakers should implement strategies to remove limitations and make this program accessible to all women.
The role of mesenchymal stem cell-derived exosome in epigenetic modifications in inflammatory diseases
Authors: Zhao Zihan , Zhang Li , Ocansey Dickson Kofi Wiredu , Wang Bo , Mao Fei
Published: May 2023

Epigenetic modification is a complex process of reversible and heritable alterations in gene function, and the combination of epigenetic and metabolic alterations is recognized as an important causative factor in diseases such as inflammatory bowel disease (IBD), osteoarthritis (OA), systemic lupus erythematosus (SLE), and even tumors. Mesenchymal stem cell (MSC) and MSC-derived exosome (MSC-EXO) are widely studied in the treatment of inflammatory diseases, where they appear to be promising therapeutic agents, partly through the potent regulation of epigenetic modifications such as DNA methylation, acetylation, phosphorylation, and expression of regulatory non-coding RNAs, which affects the occurrence and development of inflammatory diseases. In this review, we summarize the current research on the role of MSC-EXO in inflammatory diseases through their modulation of epigenetic modifications and discuss its potential application in the treatment of inflammatory diseases.