bluuebunny/crossref_metadata_2025 huggingface dataset:
Diffusion tensor imaging in differentiation of spinal cord lesions
Authors: El Masry Rowida Mahmoud , Elshafey Rasha Ahmed , Rashed Khaled Hussien , Younes Rasha Lotfy
Published: August 2024

Background

Spinal lesions sometimes remain insufficiently visualized by ‘conventional’ magnetic resonance imaging techniques; indeed very often the lesions seen on T2 weighted images do not completely display the effects of pathology on the long tracts. Diffusion imaging, which enables the imaging of molecular water motion, has been applied recently to spinal cord diseases

Aim

The purpose of this study was to assess the role of Diffusion tensor imaging in in differentiation between different spinal cord lesions

Patients & methods

This prospective study included 30 patients with myelopathy symptoms. All patients were subjected to full history taking, clinical examination, magnetic resonance imaging and diffusion tensor imaging MRI.

Results

The mean FA values at the site of the lesion was significantly lower than the normal appearing spinal cord in inflammation/demyelination, compressive myelopathy and traumatic spinal cord injury groups while the mean apparent diffusion coefficient values at the site of the lesions was significantly higher than the normal appearing spinal cord in inflammation/demyelination group. FA was sensitive than apparent diffusion coefficient in the detection of the spinal cord abnormalities with a sensitivity of 90% versus 60% respectively.

Conclusion

Diffusion tensor imaging with its quantitative indices is a non-invasive tool that is used in functional assessment of normal and pathologic spinal cord white matter, giving detailed information about different pathology and helping early management.
A novel speaker verification approach featuring multidomain acoustics based on the weighted city block Minkowski distance
Authors: Jha Khushboo , Srivastava Sumit , Jain Aruna
Published: August 2024

Access control is vital in interconnected environments like the Internet of Things, Industry 4.0, and smart connectivity, ensuring authorized access for security. Biometric‐based access, particularly speaker verification (SV), enhances security with unique vocal features, offering nonintrusive authentication with continuous monitoring. Single‐domain features prove insufficient in distinguishing similar traits, prompting latest SV advancements to adopt multidomain‐based speech features. This paradigm addresses the limitations of single‐domain features by amalgamating the merits of individual domains, establishing a cutting‐edge approach. It utilizes cepstral–frequency–time domain feature fusion, achieved via cepstral mean‐variance normalization for generalizability. The weighted city block Minkowski distance is proposed to compare reference and test speech templates. Parameters are computed based on the confusion matrix, template matching distance functions, dynamic acoustic conditions, and additive white Gaussian noise. A deep convolutional neural network classifier is assessed on open‐source LibriSpeech and Speaker in the Wild corpora, surpassing the current methodologies.
Optimizing Fused Deposition Modeling Process Parameters for Enhanced
Build Time and Mechanical Strength
Authors: EL Azzouzi Adil , Zaghar Hamid , Ziat Abderazzak , Larbi Lasri
Published: August 2024

In this study, we investigate the optimization of additive manufacturing (AM)
parameters using a bi-objective optimization approach through the non-dominated
sorting genetic algorithm II (NSGA-II). The objectives are to minimize build
time and maximize mechanical strength. Experimental evaluations are conducted on
various process parameters, including layer thickness, build orientation, and
infill density, with a focus on their impact on build time and mechanical
properties. Optimal parameter combinations, such as the lowest layer thickness,
vertical build orientation, and relatively low fill density, are identified for
maximizing tensile strength while minimizing build time. The consistency between
experimental results and those obtained through NSGA-II validation validates the
reliability of the optimization approach. Overall, this study contributes to the
advancement of AM by providing insights into efficient parameter optimization
strategies for enhancing both efficiency and performance in extrusion-based
processes.
Representing Matroids over the Reals is $\exists \mathbb R$-complete
Authors: Kim Eun Jung , de Mesmay Arnaud , Miltzow Tillmann
Published: August 2024

A matroid $M$ is an ordered pair $(E,I)$, where $E$ is a finite set called
the ground set and a collection $I\subset 2^{E}$ called the independent sets
which satisfy the conditions: (i) $\emptyset \in I$, (ii) $I'\subset I \in I$
implies $I'\in I$, and (iii) $I_1,I_2 \in I$ and $|I_1| < |I_2|$ implies that
there is an $e\in I_2$ such that $I_1\cup \{e\} \in I$. The rank $rank(M)$ of a
matroid $M$ is the maximum size of an independent set. We say that a matroid
$M=(E,I)$ is representable over the reals if there is a map $\varphi \colon E
\rightarrow \mathbb{R}^{rank(M)}$ such that $I\in I$ if and only if
$\varphi(I)$ forms a linearly independent set.
We study the problem of matroid realizability over the reals. Given a matroid
$M$, we ask whether there is a set of points in the Euclidean space
representing $M$. We show that matroid realizability is $\exists \mathbb
R$-complete, already for matroids of rank 3. The complexity class $\exists
\mathbb R$ can be defined as the family of algorithmic problems that is
polynomial-time is equivalent to determining if a multivariate polynomial with
integers coefficients has a real root.
Our methods are similar to previous methods from the literature. Yet, the
result itself was never pointed out and there is no proof readily available in
the language of computer science.
Detection of Listeria monocytogenes in cheese and in cow mastitis – a case report
Authors: Boljkovac Begić Barbara , Džafić Natalija , Barać Karmela Nina , Andreanszky Tibor , Sablić Mirela
Published: August 2024

Listeria monocytogenes is ubiquitous and causes listeriosis, which manifests in animals in the form of septicaemia, encephalitis, abortions, and, rarely, mastitis. In humans, food is the main source of infection, which is the reason food business operators take samples and test for Listeria. We report a case of L. monocytogenesdetection in traditional cheese made from raw milk, and subsequent investigation revealed that L. monocytogenes was excreted from a cow mammary gland. Although treatment was carried out according to the results of the antibiogram, there was no improvement in the subclinical mastitis and the excretion of L. monocytogenes after treatment was 8.8x102cfu/mL, and therefore the cow was removed from the herd.
Antimicrobial effectiveness of chestnut honey, pollen and propolis individually and in combination
Authors: Čengić Benjamin , Rondić Medina , Jerković-Mujkić Anesa , Šarić-Medić Belmina , Magoda Amina , Ćutuk Amel , Bejdić Pamela , Šerić-Haračić Sabina , Maksimović Alan
Published: August 2024

The emergence of bacteria with antibiotic resistance and multiple resistance is characteristic of animal and human pathogens. It is wide known that bee products, which have been used in alternative medicine since ancient times, have antimicrobial potential. Application of bee products for therapeutic purposes is defined as apitherapy. The study aimed to evaluate the antimicrobial activity of commercial chestnut honey, pollen and propolis produced in western Bosnia and Herzegovina (Sanski Most) individually and in five combinations (apimixtures). The antimicrobial properties of samples were investigated using the agar well diffusion method against three Gram-positive bacteria (Bacillus subtilis subsp. spizizenii ATCC 6633, Methicillin-resistant Staphylococcus aureus ATCC 33591, Enterococcus faecalis ATCC 29212); three Gram-negative bacteria (ESBL producing Escherichia coli ATCC 35218, Salmonella enterica subsp. enterica serovar Enteritidis ATCC 13076, Pseudomonas aeruginosa ATCC 9027) and one fungal species (Candida albicans ATCC 10231). Pure bee pollen inhibited the growth of only Gram-negative bacteria, concentrated chestnut honey was active against all Gram-negative and Gram-positivebacteria, while 20% propolis extract and apimixtures A2 (80% honey and 20% propolis) and A3 (60% honey, 20% pollen and 20% propolis extract) inhibited the growth of all tested microorganisms. Chestnut honey andthree apimixtures (A1, A2 and A3) showed the highest antibacterial action against all tested Gram-negative bacteria and MRSA compared to other investigated samples. In this study, examined honeybee products from Bosnia and Herzegovina and their mixtures had significant activity against tested bacteria, including strains with proven resistance to conventional antibiotics, MRSA and ESBL producing E. coli.
Assessment of Novel Haematological Inflammatory Markers (NLR, SII, and SIRI) as Predictors of SIRS in Dogs with Canine Monocytic Ehrlichiosis
Authors: Erdogan Hasan , Ozalp Tahir , Erdogan Songul , Ural Kerem
Published: August 2024

Canine monocytic ehrlichiosis (CME) is a tick-borne and fatal disease that induces a systemic inflammatory response syndrome (SIRS), which underscores the importance of assessing the level of inflammation. In this study, we aimed to evaluate changes in the SII and SIRI indexes in dogs with CME based on the presence of SIRS criteria. A total of 53 dogs affected with CME and 13 healthy dogs were included in the study. Haematological data, including neutrophil to lymphocyte ratio (NLR), systemic inflammatory index (SII), and systemic inflammatory response index (SIRI), were collected and statistically compared between groups based on SIRS status. The NLR and SIRI indexes were significantly higher in dogs with CME that meet the criteria for SIRS compared to dogs without SIRS and healthy controls. In summary, monitoring the SIRI index can aid in evaluating SIRS criteria in dogs with CME, which can help improve their treatment and overall prognosis.
Current application of proteomics in the veterinary field – a short summary and literature review
Authors: Kajin Filip , Šmit Iva , Stevanović Vladimir , Rešetar Maslov Dina , Rubić Ivana , Mrljak Vladimir , Kuleš Josipa
Published: August 2024

The biomedical research field’s continuous search for innovative technologies has led to improved disease diagnosis, novel drug discovery, and therapeutic interventions, all aimed at enhancing animal and human health alike. In this context, proteomics has emerged as a critical new technology, focusing on detailed examinations of protein composition, abundance, structure, function, and interactions. Proteomics, the study of the entire set ofproteins expressed by an organism, plays a crucial role in disease diagnosis, drug discovery, and therapeutic interventions in both human and animal health. Proteomics in veterinary medicine and animal health is an evolving field that holds significant promise for fundamental and applied discoveries related to the biology and pathology of domestic and companion species. It encompasses a broad spectrum of applications, including disease diagnosis, comparative medicine, pharmacology, nutrition, reproductive biology, livestock production,and pathology. By analysing protein profiles and interactions, proteomics contributes to enhancing animal health, welfare, and productivity across various fields of veterinary research and practice. Experimental proteomics in domestic animals offers advantages over the use of rodents, such as the ability to conduct multipletime-series samplings of biological samples for extensive analysis, allowing for the investigation of experimental and natural disease processes. This review highlights the current application of proteomics in veterinary medicine, focusing on its potential to advance diagnostics, research, and treatments in veterinary science. The current limitations of proteomics are also discussed.
Međusobni utjecaj reproduktivnog statusa, dobi i osobnosti konja na ostvarivanje punog atletskog potencijala u natjecanjima u preponskom jahanju
Authors: Prvanović Babić Nikica , Rački Antea , Vlahek Ivan , Butković Ivan , Šavorić Juraj , Lojkić Martina , Maćešić Nino , Getz Iva
Published: August 2024

The study analysed the results of showjumping competitions of 41 warmblood horses of varying reproductive status, age and personality. In total, 8 stallions, 18 mares, and 15 geldings were included. Horses were divided in the following age groups: young horses 4-7 years old (n=15), mature horses 8-13 years old (n=13) and older horses 14-20 years old (n=13). Horses were also divided according to dominant personality component, obtained by questionnaires: excitability (n=4), protection (n=7), sociability (n=15), curiosity (n=9), horses without a dominant personality component (n=6). Horses in this study were compared to the results of showjumping competitions of the Croatian Equestrian Federation in the past two consecutive years, considering data from 80 classes, 44 tournaments and 3280 starts. The Winter Cup (1.10-1.3) was considered the time of absence of cyclicity in mares while the Summer Cup (1.3-1.10) was considered the full season of reproductive cyclicity of mares. The aim of the study was to determine correlations between the dominant personality component, reproductive status and age of the horse in obtaining optimal results in showjumping competitions. Based on the results, the dominant personality component positively influences the horse’s success in showjumping(ranking, penalties). Excitable horses had the poorest results, especially during the reproductive season (P<0.05). Protective horses had the best results regardless of season. It is likely that determination of the dominantpersonality component could help in better selection of showjumping horses. Geldings had the least seasonal variations, while mares had significantly better results out of season (P<0.05). Stallions also had better results out of season, though the difference was not statistically significant. Recommendations include introducing methods of cycle blockage in mares to improve focus and results in all categories. Contrary to expectations, older horses (14-20 years old) obtained better results than mature horses (8-13 years old). Further research of all observed parameters on a significantly higher sample of showjumpers is required to determine whether the findings here could be applied to the complete population of warmblood horses used in showjumping competitions in Croatia and abroad.
Biochemical characteristics of E. coli isolated from food of animal origin
Authors: Tomašković Dora , Hlebić Lucija , Peinović Lovran , Humski Andrea
Published: August 2024

Food of animal origin is a potential source of pathogenic E. coli that are dangerous to humans. While most strains are intestinal commensals, some can cause intestinal and extraintestinal infections. Their pathogenicity is associated with the presence of virulence genes, phylo-group and, in some strains, biochemical characteristics. In this study, a total of 61 E. coli isolates from meat, minced meat, meat preparations and carcass swabs from different animal species were analysed. The biochemical properties of the strains were determined using VITEK2 system and the data was compared with the presence of virulence genes from previous studies. The results showed a correlation between the presence of the eae virulence gene and the alkalinization of succinate. In addition, the presence of the virulence gene cnf1 was correlated with the enzyme tyrosine arylamidase, though the correlation between biochemical characteristics and the presence of virulence genes is questionable due to the small sample size and more strains need to be tested for further conclusions. Although no significant correlations were found between biochemical characteristics and the presence of virulence genes, this study describes the diversity of E. coli in the Republic of Croatia. The collected data also reveal new insights into biochemical characteristics of E. coli isolated from domestic and wild animals in the Republic of Croatia.
Shannon entropy and thermodynamic properties of an inversely quadratic Yukawa potential model
Authors: Onate Clement , Okon I. B. , Akinpelu J. A. , Ajani O. O. , Adedewe Olorunfemi , Deji-Jinadu B. B.
Published: August 2024

An inversely quadratic Yukawa potential is an exponential-type potential that has received little attention only in the bound state to the best of our understanding. This study obtained the solution of the Schrödinger equation for an inversely quadratic Yukawa potential via parametric Nikiforov-Uvarov method and supersymmetric approach. Some thermodynamic properties (vibrational enthalpy, vibrational Gibbs free energy and vibrational entropy) for the Inversely quadratic Yukawa potential are examined. The study is also applied to shannon entropy as the theoretic quantity. The results obtained showed that the energy eigenvalue for the potential goes in the opposite direction with the quantum state and the screening parameter. The Shannon entropy obtained as a function of the potential strength only obeyed the Heinsenberg principle at the ground state and excited states. In both cases, the also satisfied Bialynick-Birula, Mycielski inequality. It is noted that the thermal properties studied as a function of the temperature, even though the studied potential is not a molecular potential, the results followed the trend of the molecular potential.
Alberti, Eleonora-Noga. Triángulo judeoespañol. Canciones sefardíes de Jerusalén en Asunción y Buenos Aires. Asunción del Paraguay: servilibro, 2022, 198 pp. ISBN: 978-99925-16-01-0
Authors: Musri Fátima Graciela
Published: August 2024

Este libro relata la historia de Eleonora Angélica [Noga] Alberti en primera persona, mientras realizó su investigación y recolección de canciones sefardíes, que viajaron desde España hacia Argentina y Paraguay en la voz de familias emigrantes. De allí el título de la publicación, “triángulo” judeoespañol. El libro de Alberti se instala como una contribución original a los intereses actuales de la musicología referidos a la autobiografía, a los estudios migratorios intercontinentales de un repertorio milenario y a su pervivencia oral en tanto herencia cultural.
Aldemaro Romero y su Onda Nueva (1968-1976): confluencia y diálogo entre músicas tradicionales y populares urbanas en Venezuela
Authors: Riascos Aguirre Susana
Published: August 2024

Aldemaro Romero conjugó las músicas tradicionales venezolanas anteriores a 1968, con rasgos de modernidad provenientes de fuentes foráneas como el jazz y la bossanova, para crear la Onda Nueva, una música popular urbana producida y consumida en la Venezuela de finales de la década de los años sesenta. Esta música se caracterizaba por una poderosa identidad, novedosa y sin precedentes, capaz de operar desde el plano estético y taxonómico, al triple nivel musical de movimiento, género y estilo. Esta triple confluencia musical resalta por su actual supervivencia en las músicas populares urbanas venezolanas de raíz tradicional y su potencialidad como canal de diálogo con músicas internacionales, tanto del campo popular como del académico.
Multilayer Perceptron Network to Detect Fraud in Digital Images
Authors: Alkhoja Omnea
Published: August 2024

The major challenge of data authenticity is how to check for image fraud, which createsa huge problemforthe credibility of visual media. In this paper, we proposea method to investigatethe performanceof a Multilayer Perceptron (MLP)to extract the fraud images,this network is a classof supervised Artificial Neural Network(ANN. Theproposal modelappliesMLP modelto allocateextracted image features in order to distinguishthembetween realand modifiedcontents. Theexaminedfeatures are includedwithinstatistical matrices, analysis of histogramspace, and possible inequality that may arise during modifications. The proposed MLP wastrained withdataset that contains both realand fraudulent images, thus allowing the modelto extractknowledge from the originalpatterns that differentiate between those two classes. The model's performance wasvalidated with severalmetrics, including accuracy,precision,and computational cost. Furthermore,this paper presentscomparisons against traditional methods that were examined in the procedure. The finding of this work enhances the model withimprovedimage fraud detection by showcasing the capabilities of MLPs within 162.59 seconds to 86% detection, while the base algorithm in 205.92 seconds succeeded in recognizing 82%.
Arabic Text Steganography: Literature Survey
Authors: Abdul-rahman Nadia , Shakir Salwa
Published: August 2024

The use of strong encryption and hiding techniques is essential for secure digital communication. The aim of this article is to give a thorough study of advanced steganography methods designed especially for embedding information in Arabic text, which may be sensitive in nature and needs to be transmitted securely. This review is focusedon four main criteria; embedding rate, invisibility, robustness against detection, and text quality. We conducted a comprehensive survey of text steganography and examined its distinct characteristics, including the nature of the script, accents, and linguistic rules. Several researchers have utilized these distinct characteristics of Arabic writing for developing a number of techniques for embedding information. This article gives a detailed analysis of the strengths, weaknesses, possible applications, and major challenges. The conclusions of this review can help researchers and practitioners to select an ideal method according to their own needs regarding storage capacity, security, and text quality. Moreover, the article underscores the need for giving priority to Arabic text steganography which has become highly important as the use of hidden communication increases in Arabic-speaking communities, while also preserving the cultural and linguistic integrity
Load Balancing in Cloud Computing Using Meta-Heuristic Algorithm: Survey
Authors: Hadi Aliaa Ayoob , Hallawi Huda
Published: August 2024

Load balancing is essential within the cloud. Distributing the workload over many servers permits for a more efficient machine. Optimal resource use, decreased time to response, and more advantageous gadget performance are all results. Among the numerous challenges that traditional methods of accomplishing equilibrium come upon are problems with adaptability and the unpredictability of cloud structures. This survey focuses on the demanding situations associated with load balancing in cloud computing and proposes the usage of specialized algorithms as an answer. It determines the most reliable alternatives for facts placement in the cloud. Meta-heuristic algorithms draw concept from herbal approaches, which includes the foraging behavior of ants or the hunting strategies of predators. These algorithms excel at rapidly finding super answers in situations where conventional optimization algorithms fail to get great results. Various strategies have been proposed to attain paintings equilibrium in cloud computing. Evidence has shown that these techniques can enhance work balance in cloud computing.
Coverless Information Hiding Based onDeep Learning Approach:Review
Authors: Al-Shably Zainab Hdeib , Hashim Asaad Noori
Published: August 2024

The proliferation of digitalization in the realm of information has paved the way for numerous types of multimedia data to be attacked. Hence, the security of information has become a critical concern. Over the years, image steganography has been widely acknowledged as one of the most effective techniques for securing confidential information. This methodology comprises the integration of sensitive information into a cover image via the manipulation of specific pixels, resulting in the formation of a steganography image. However, it is imperative to note that such manipulations could be identified by steganalysis algorithms, thus undermining the security of the message. To address the aforementioned concern, the notion of coverless image steganography has been introduced, which serves as a promising solution. The coverless image steganography technique entails the establishment of a mapping correlation between the content of the clandestine message and the cover images, while leaving the cover images unaltered. This review article meticulously scrutinizes the recent studies on coverless image steganography, thereby furnishing significant and profound insights into the techniques
An Approach for Hybrid Optimal Power Flow Strategies with Optimal Allocation of Distributed Generators for a Power Network
Authors: Abdulkhaleq Ayat Saad , Al-Jubori Waleed Khalid Shakir
Published: August 2024

The OPF difficulties are characterized by the presence of four distinct objective functionswhich are: active powerlosses,fuel operating costs and voltage variations. The volatile and variable nature of distributed generator (DG) sources contributes to the convolutionof the optimum power flow (OPF) issue. This paperemployed bat algorithms to tackle the issue of optimumpower flow (OPF)and PSO algorithm to optimal allocation of DG. The goal was to enhance the effectiveness of energy use, environmental sustainability, and cost efficiency of the electricity grid. The test cases include a wide range of scenarios, including the existence of Distributed Generation (DG), different locations of DG within the network, various kinds of load expansion, and occasional breakdowns of transmission lines. These possibilities are considered in order to address the problem presented by the suggested solution OPF. The incidents are assessed utilizing bus systems, such as the 30 bus systemin MATLAB.
Efeitos do Recurso Especial n. 1.759.081/SP sobre a Tributação de Serviços Técnicos
Authors: De Athayde Mendonça Victória
Published: August 2024

Este estudo tem por objetivo analisar os impactos do Recurso Especial n. 1.759.081/SP (“REsp n. 1.759.081/SP” ou “Caso Engecorps”), recentemente julgado pelo Superior Tribunal de Justiça (“STJ” ou “Corte Superior”), na tributação de remessas ao exterior para pagamento de serviços técnicos prestados por pessoa jurídica que não possua estabelecimento permanente no Brasil. Aborda o aparente conflito entre os arts. 7º, 12 e 14 das Convenções Internacionais para evitar a Dupla Tributação e prevenir a Evasão Fiscal em Matéria de Impostos sobre a Renda, no modelo OCDE (“Convenções” ou “Acordos”), com o intuito de, com lastro no posicionamento do STJ no REsp n. 1.759.081/SP, analisar a lógica atualmente aplicada de enquadramento de valores remetidos ao exterior como contraprestação de serviços técnicos. Em especial, analisa o escopo de aplicabilidade do art. 14, no que se refere a pessoas físicas e sua extensão a pessoas jurídicas, além de seu escopo objetivo.
Delineamento da Transação Controlada na Nova Lei de Preços de Transferência
Authors: Gregorio Ricardo Marozzi
Published: August 2024

Com a edição da Lei n. 14.596/2023, o Brasil finalmente conciliou suas regras de controle dos preços de transferência com o padrão arm’s length. Uma etapa essencial da análise que envolve esse padrão é o delineamento da transação controlada. O presente artigo examina detalhadamente os elementos que devem ser identificados na referida etapa, isto é, as relações comerciais ou financeiras e as características economicamente relevantes. Em seguida, são apresentados também os fundamentos do teste de racionalidade comercial que a lei impõe à transação delineada e discutida a sua compatibilidade com as cláusulas gerais antielisivas.
ANALISIS MODEL MATEMATIKA SEIRS TERHADAP KECANDUAN GAME ONLINE SISWA SMPN 3 MANDREHE BARAT
Authors:   Universitas Muslim Nusantara Al-Washliyah, Waruwu Nove Susanti , Panjaitan Dedy Juliandri , Firmansyah Firmansyah
Published: August 2024

This research uses documentation and experimental methods. The documentation method is used to create and develop the SEIRS model in cases of online game addiction. Meanwhile, the experimental method is a research method to find answers or solutions to a case or research object. This research was conducted on students in class VIII UPTD SMP Negeri 3 Mandrehe Barat with a total of 26 students within 14 days. In this study, researchers modeled cases of online game addiction into the SEIRS model using the 5th-order Runge-Kutta method so that its effectiveness was obtained based on the data obtained. The results of this study show that the Runge Kutta method is the most effective in the Seirs mathematical model for online game addiction.
PRO-INFLAMASI VERSUS ANTI-INFLAMASI SITOKIN: MITOS ATAU KENYATAAN
Authors:   Universitas Methodist Indonesia, Pasaribu Sumihar M. R.
Published: August 2024

Inflammation is characterized by interactions between pro- and anti-inflammatory cytokines. Cytokines are generally classified in one or another category: interleukin-1 (IL-1), tumor necrosis factor (TNF), gamma-interferon (IFN-γ), IL-12, IL-18 and granulocyte-macrophage colony-stimulating factor, . classified as pro-inflammatory cytokines while IL-4, IL-10, IL-13, IFN-α and transforming growth factor-β are anti-inflammatory cytokines. In this review, it is demonstrated that this classification is too simplistic and provides many examples illustrating that certain cytokines can behave as both pro- and anti-inflammatory cytokines. It is true, the amount of cytokines, the nature of the target cells, the nature of the activation signal, the nature of the cytokines produced, the timing, the order of action of the cytokines and even the experimental model are parameters that greatly influence the properties of the cytokines.
HUBUNGAN NILAI HEMATOKRIT DAN JUMLAH TROMBOSIT TERHADAP DERAJAT III DAN IV PASIEN DEMAM BERDARAH DENGUE DI RSUD DR. PIRNGADI KOTA MEDAN TAHUN 2022
Authors:   Universitas Methodist Indonesia, Marpaung Alexander Parlindungan , Sembiring Lidia Henni , Silangit Thomas
Published: August 2024

Dengue Hemorrhagic Fever (DHF) is a disease condition caused by a dengue virus infection. DENV-1, DENV-2, DENV-3, and DENV-4 are serotypes of the virus and are usually transmitted through the bite of mosquitoes from the stegomyia family, such as Aedes aegypti and Aedes albopictus. DHF often results in extraordinary events (KLB) and can lead to death. The disease can be categorized into four different clinical stages: stages I, II, III, and IV. Laboratory examination in DHF usually shows a decrease in platelet count below 100,000/µl and the presence of leaky plasma, which can be seen from the hematocrit that has increased by more than 20%. Objective to determine whether there is a relationship between hematocrit value and platelet count at degrees III and IV in DHF incidence. This type of research uses an observational analytic study with a cross-sectional approach. In the analysis, there is a significant relationship between hematocrit value and clinical degrees III and IV with a value of p = 0.043, and there is a relationship between platelet counts and clinical degrees III and IV with a value of p = 0.000. There is a relationship between hematocrit value and platelet count in clinical degrees III and IV of DHF.
INVOLVEMENT OF TUBERCULOUS MENINGITIS PATIENT WITH HOSPITAL ACQUIRED PNEUMONIAE Case Report
Authors:   Rumah Sakil Putri Hijau Medan, Pakpahan Edwin Anto , Alamsyah Raja Iqbal , Hermanto Tsaniya Difa , Nasution Reyhan Khaira Helminta , Mahardika Virani , Daulay Kanina Hatia Putri
Published: August 2024

Meningitis is a global public health problem. The causes can be viruses, bacteria, fungi and parasites. Meningitis is an infectious disease that cannot be overcome and is still a problem in developing countries. As a developing country Indonesia, Tuberculosis has a high number of cases throughout the year. Tuberculous meningitis (TB) is an infection byMycobacterium tuberculosisabout meningor brain parenchyma resulting variety morbidity and mortality. A 39 years old woman came to the emergency room at Drs. H. Amri Tambunan complained of seizures 1 day ago with a duration of more than 1 hour. Seizures are found throughout the body. Also a fever was found 1 day today. Shortness of breath and cough were found for the past 3 days. Decreased appetite has been observed for the past 1 week. There was no history of nausea and vomiting. Os post VP shunt installation on May 29th, 2023. Female patient, 39 years old, with a diagnosis of Tuberculous Meningitis with Hospital Acquired Pneumoniae has been hospitalized from 9 to 20 September of 2023. And also outpatient treatment at the Pulmonology Departement is recommended.
POTENSI LABU SIAM SEBAGAI ANALGETIK
Authors:   Universitas Methodist Indonesia, Sinatra Jadeny , Siahaan Jekson M.
Published: August 2024

Pain is an unpleasant emotional sensation. Pain can begin after inflammation and/or after tissue damage. The use of analgesic or anti-pain drugs so far has undesirable side effects, so people have begun to look for alternative traditional medicines as a substitute. One of the plants that can be used as an alternative medicine for analgesics is chayote (S. edule). The purpose of this review is to provide information about chayote as an analgesic. This study focused on reviewing articles on experimental studies conducted in vivo and its bioactive components.
IDENTIFIKASI BAKTERI DIPLOCOCCUS GRAM NEGATIF DENGAN PEWARNAAN GRAM PADA SAMPEL SWAB ANAL KASUS SODOMI ANAK DI RSUD DR. PIRNGADI KOTA MEDAN PERIODE MEI 2022 – OKTOBER 2023
Authors:   Universitas Methodist Indonesia, Nainggolan Renatha
Published: August 2024

Gram stain is a type of microbiological examination to classify Gram positive and Gram negative germs based on the chemical and physical properties of the germ cell wall. Sexually transmitted infections (STIs) are infectious diseases that are transmitted mainly through sexual intercourse. Sexually transmitted bacteria are including Chlamydia trachomatis (chlamydia), Treponema pallidum (syphilis) and Neisseria gonorrhoeae. Sodomy is a form of sexual abuse. This behavior can also be categorized as anal sex. This act of abuse has a deep psychological trauma and long-term impact on the victim. The act of sodomy will certainly have a negative physical impact on the victim, both in the form of wounds in the anus and the risk of contracting STIs. This study is a retrospective descriptive study aimed at identifying gram negative bacteria with Gram Stain. Data collection through secondary data of gram staining of anal swabs in sodomy cases obtained from laboratory medical records of RSUD Dr. Pirngadi Kota Medan for the period May 2022 to October 2023. The results showed that those infected with gram negative Diplococcus from anal swab samples of sodomy cases were 10 cases (67%) out of 15 cases of sodomy in children. More boys were sodomized, namely 11 people (73%), and girls 4 people (27%). The highest age group was 11-15 years old with 9 cases (60%), 6-10 years old with 3 cases (20%) and 1-5 years old with 3 cases (20%). Gram-negative Diplococcus bacteria can be identified by Gram staining of anal swabs of child sodomy cases.
Perancangan Sistem Informasi Akademik pada SD Holistic Children Center Berbasis Web
Authors:   Universitas Methodist Indonesia, Tumanggor Ika Lestari , Jamaluddin Jamaluddin , Lumbantoruan Gortap
Published: August 2024

In an increasingly competitive educational landscape, many institutions are seeking technologies that enhance performance. An academic information system is a system developed to manage academic data using computer technology, transforming academic processes into useful information. This research aims to design a web-based academic information system at Holistic Children Center Elementary School. Currently, the management of academic data at the school is conducted manually using books and Microsoft Excel, which is prone to data loss and inefficient in tracking academic information. The implementation of an academic information system with a centralized database method is expected to improve the effectiveness and efficiency of academic data management and support the enhancement of the school's accreditation. The research methods employed include direct observation, interviews with school officials, and literature studies to obtain relevant theories and methods. The results indicate that the designed academic information system can manage data centrally and structurally, facilitating information presentation for teachers, students, and parents. Additionally, this system can enhance the school's reputation through more organized and integrated data management and simplify the tracking and documentation of alumni.
Peran Kepemimpinan dalam Pengembangan Sistem Pemerintahan Berbasis Elektronik (SPBE) di Kota Medan
Authors:   Universitas Negeri Medan, Purba Widya Helen Anjalina , Sinaga Eko Pranata , Ivanna Julia
Published: August 2024

This research explores the role of leadership in the development of Electronic Government Systems (EGS) in Medan City. Using a qualitative approach with a literature review research design, the study analyzes how leadership influences the implementation of information technology in government administration. Findings indicate that strong and technology-oriented leadership can inspire innovation and transformation in EGS, facilitate community involvement, and enhance public service efficiency. Managerial and policy implications are outlined to support the sustainable development of EGS in Medan City.
Penerapan Service Quality pada Kajian Aspek Pasar Studi Kelayakan Usaha Cafe Bukit Soka
Authors:   Universitas Kristen Satya Wacana, Wibowo Dianta Ricky , Setyanti Dina Budi , Putri Evellyn Diva , Atahau Apriani Dorkas Rambu
Published: August 2024

After the Covid-19 pandemic, Wisma Baptis Bukit Soka Salatiga, which is supported by the Indonesian Baptist Foundation, has plans to establish a new business, Cafe Bukit Soka. This community service activity was carried out to assist the Indonesian Baptist Foundation in observing the establishment of a new business, Cafe Bukit Soka. Observations were carried out by reviewing market aspects using the service quality method while also conducting direct observations in the field. In the survey that has been carried out, service quality indicators are used which consist of physical evidence, reliability, responsiveness, guarantee and attention. The results of observations through a market survey obtained 50 respondents who had the perception that Cafe Bukit Soka would provide adequate facilities, be responsive to consumer complaints and desires, reliable in serving consumers, guarantee safety and comfort, and pay attention to every consumer's needs. This analysis was prepared in the form of a report which was then submitted to Wisma Bukit Soka Salatiga to be used as a reference in establishing a new business, Cafe Bukit Soka.
Evaluasi Hasil Pembangunan Penampungan Air Minum Masyarakat Desa Silima Banua Umbunasi Kecamatan Ulu Idanotae Kabupaten Nias Selatan
Authors:   Universitas Pembinaan Masyarakat Indonesia, Hani Sheila , Rini Rini , Nasution Ridwan , Setiawan Luther
Published: August 2024

Access to clean water in Silima Banua Village is a quite complex problem. The government then carried out construction of community drinking water reservoirs. After construction was completed, research was carried out on drinking water reservoirs. This research examines the impact of the construction of drinking water reservoirs on the availability of clean water, public health and the quality of infrastructure in Silimabanua Umbunasi Village, South Nias Regency. Data was collected through surveys, interviews, and field observations to analyze changes in access to clean water before and after development, its impact on public health, and the physical quality of water reservoirs. The research results show a significant increase in the availability of clean water after construction, which positively affects public health. Apart from that, the physical quality of the water reservoir is assessed as meeting established standards. Community participation, local government support, and drinking water quality were also identified as important factors in the success of this project.
Peran Ukuran Perusahaan dalam Memoderasi Hubungan Profitabilitas, Likuiditas dan Struktur Modal dengan Kualitas Laba
Authors:   Universitas Mikroskil, Br. Ginting Suriani , Tarihoran Anita , Gultom Robinhot ,   Universitas Methodist Indonesia
Published: August 2024

This research aims to determine and analyze the role of company size in moderating the relationship between profitability, liquidity capital structure, and earnings quality. The research object is a manufacturing company listed on the Indonesia Stock Exchange for the 2017-2021 period. The sampling technique was carried out using purposive sampling and a sample of 72 companies was obtained. The data analysis method is multiple linear regression analysis and absolute difference value testing using the SPSS data processing application. The research results show that capital structure has a significant effect on earnings quality, but profitability and liquidity do not have a significant effect on earnings quality. The results of the moderation test show that company size is unable to moderate the relationship between profitability, liquidity capital structure, and earnings quality.
Pengaruh Citra Merek dan Harga Terhadap Keputusan Pembelian Ulang Dengan Kepuasan Konsumen Sebagai Variabel Intervening pada Gapyeong Korean BBQ Setia Budi Medan
Authors:   Universitas Mikroskil, Marpaung Rahel Olivia , Sigalingging Safelya , Hutasoit Apren Halomoan , Tarigan Purnaya Sari
Published: August 2024

The study aims to find out the impact of brand image and price on customer satisfaction re-purchase decisions as an intervening variable on Gapyeong Korean BBQ. This research uses a quantitative method of causal research with primary data taken from the dissemination of the questionnaire. The sample used in this study was 100 respondents who made a purchase at Gapyeong Korean BBQ. This study uses a non-probability sampling technique, namely purposive sampling using the Slovin formula. Slovin is a formula used to find large samples that are estimated to represent the entire population. The data analysis technique in this study uses (SEM) structural equation modeling using the help of smart-PLS to solve the formula problems and hypotheses that have been formulated in this research as well as used to test the relationship between variables. The results of this study showed that brand image did not have a significant impact on consumer satisfaction, price had a significant influence on cosmopolitan satisfaction, brand image had no significant effect on re-purchase decisions, price did not significantly influence re-purchase decisions, customer satisfaction had no significant impact on resupply decisions, consumers satisfaction could not mediate the influence of brand image variables on resumption decisions, and consumers satisfaction couldn’t mediate price on resuspension decisions.
PERAN KEUNGGULAN BERSAING DALAM MEMEDIASI PENGARUH RASIO KEUANGAN TERHADAP NILAI PERUSAHAAN PADA PERUSAHAAN SEKTOR KESEHATAN YANG TERDAFTAR DI BURSA EFEK INDONESIA PERIODE 2015-2021
Authors:   Universitas Methodist Indonesia, Sinulingga Sella Monica , Sianturi Jeudi Agustina T. P. , Melianna Saur
Published: August 2024

Tujuan dari penelitian ini adalah untuk mendapatkan bukti empiris dari peran keunggulan bersaing dalam memediasi pengaruh rasio keuangan terhadap nilai perusahaan pada perusahaan sektor kesehatan yang terdaftar di Bursa Efek Indonesia. Sampel yang digunakan dalam penelitian ini adalah seluruh perusahaan sektor kesehatan yang terdaftar di Bursa Efek Indonesia periode 2015-2021 yang telah memenuhi kriteria. Terdapat delapan perusahaan yang memenuhi kriteria yang dapat dijadikan sampel dalam penelitian ini. Analisis perangkat lunak yang digunakan dalam penelitian ini adalah WarpPLS versi 8.0. Hasil dari penelitian ini menunjukan bahwa variabel likuiditas (CR) berpengaruh positif dan signifikan terhadap nilai perusahaan, solvabilitas (DAR) berpengaruh negatif terhadap nilai perusahaan, aktivitas (TATO) berpengaruh positif dan signifikan terhadap nilai perusahan dan profitabilitas (ROA) yang secara langsung memberikan pengaruh positif namu tidak signifikan terhadap nilai perusahaan. Hasil pengujian membuktikan bahwa keunggulan bersaing (EVA) dapat memediasi pengaruh profitabilitas (ROA) terhadap nilai perusahaan.
PENGARUH KUALITAS KEHIDUPAN KERJA, PELATIHAN, DAN IKLIM ORGANISASI TERHADAP KEPUASAN KERJA PADA DINAS KEPENDUDUKAN DAN PENCATATAN SIPIL KABUPATEN KARO
Authors:   Universitas Methodist Indonesia, Br. Barus Apriyanti , Winarto Winarto , Siregar Selamat
Published: August 2024

The purpose of this study was to determine and analyze the quality of work life, training, and organizational climate on job satisfaction at the Karo Regency Population and Civil Registration Office. The quality of work life, training, organizational climate simultaneously has a positive and significant effect on job satisfaction of the Karo Regency Population and Civil Registration Service employees. the type of data is quantitative data with a saturated sample of 34 respondents. This study concludes that the quality of work life has a partially significant positive effect on job satisfaction of the Karo Regency Population and Civil Registry employees. Partial training has a positive and significant effect on job satisfaction of the Karo Regency Population and Civil Registry Office employees. Partial training has a positive and significant effect on job satisfaction of the Karo Regency Population and Civil Registry Office employees. Adjusted R Square value of 0.921 means 92.1% job satisfaction of Karo Regency Population and Civil Registry employees can be explained by Quality of Work Life, Training, and Organizational Climate. While the remaining 7.9% is explained by other factors not examined in this study.
PENGARUH PROFITABILITAS, LIKUIDITAS, DAN LEVERAGE TERHADAP NILAI PERUSHAAN PADA PERUSAHAAN SUB SEKTOR OTOMOTIF DAN KOMPONENNYA YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors:   Sekolah Tinggi Ilmu Ekonomi Pangeran Antasari, David David , Diana Diana , Hasibuan M. Fikri Caesarandi
Published: August 2024

This research aims to determine the effect of profitability, liquidity and leverage on company value in automotive sub-sector companies and their components listed on the Indonesia Stock Exchange in 2015 - 2020. The sample obtained was 9 automotive sub-sector companies and their components listed on the IDX in 2015 - 2020 with a total of 54 observation data over 6 years of observation. The data collection technique used is documentation with data sources using secondary data taken through the official website of the Indonesian Stock Exchange. The data analysis technique used in this research is multiple linear regression analysis using SPSS 26 software. The results of this research show that profitability has a significant effect on company value. Liquidity does not have a significant effect on company value. Leverage affects company value. Then there is the effect of profitability, liquidity and leverage and on company value simultaneously