bluuebunny/crossref_metadata_2025 huggingface dataset:
Importance and Feasibility of Teaching Cantonese Opera Culture in Singapore
Authors: Han Xue
Published: September 2024

As Singapore increasingly values diverse cultural expressions, there is growing recognition of the cultural significance and social impact of Cantonese opera. In the current context, there is a trend towards exploring the feasibility and significance of integrating Cantonese opera into international Chinese education in Singapore. This initiative aims to delve into the cultural significance of Cantonese opera as an iconic art form with substantial social influence, emphasizing the unique emotional connection Singaporeans have with it, and the imperative for China to encourage cultural communication. The feasibility section underscores that teaching Cantonese opera in Singapore is supported by strong governmental backing, ample educational resources, and keen interest among Singaporean students.
The Impact of ESG Factors on Industries: The Case of China
Authors: Zhang Chenyiming
Published: September 2024

The ESG factors consideration has shown an upward trend since half century ago, as well as in China since the 21st century. The Chinese governance has required institutions and companies include ESG scores in the company’s reports and make information of corporations being transparent to the public. This paper analyzes which industry or market are sensitive and will be influenced by considering ESG factors in the near future based in China. By means of collecting relative research theories and conclusions, this paper presents three industries that are possible to be impacted by ESG. Technically, there are numerous industries would be affected, but this paper focuses on three of the most well-known and sensitive markets-financial market, sinful market, and green industries. This paper is able to help investors or individuals who wants to invest and even the governance to recognize the future tendencies of several markets and it’s useful to aware in advance for investment worthful industries.
The Impact of Enterprise ESG Performance on Business Strategy: Taking Procter & Gamble as an Example
Authors: Li Shanglin
Published: September 2024

In today's era of rapid development of the green economy, environmental protection has become a global consensus. Environmental, Social and Governance (ESG) is an emerging investment concept and enterprise evaluation standard that measures the sustainable development capabilities of enterprises. ESG performance reflects a company's contribution to the environment and society, as well as the effectiveness of its internal governance. This paper will explain the impact of ESG performance on Procter & Gamble (P&G) from three aspects of ESG. Analyze the current problems of P&G Company based on three cases, such as company product innovation design, inappropriate marketing topics and insufficient coordination between the company’s production and logistics processes. The analysis results show that corporate innovation should be promoted, companies should be further encouraged to strengthen ESG construction and the company's products still need to be enhanced with innovative designs that help protect the environment. If companies cannot be green and environmentally friendly in their production and operation processes, their long-term development will be threatened.
A Company Analysis and Financial Assessment of Microsoft
Authors: Yan Zihan
Published: September 2024

As a large enterprise that is almost well-known in the software market, Microsoft will naturally become the investment candidate of many investors because of its high visibility and broad coverage of the market. At this time, whether Microsoft is worth investors' investment has become a problem worth studying. In this regard, this paper analyzes and studies the investment value of Microsoft. By analyzing Microsoft's strengths, weaknesses, opportunities and threats (SWOT analysis framework), comparing the growth or decline of Microsoft's financial reporting data this year and last year, comparing the horizontal data ratio with other companies in the same market, and studying the development risks existing in the software market and the company itself, this paper concludes that investing in Microsoft is a result of both opportunities and risks. It is concluded that Microsoft is worth investing in, but investors should consider whether they can bear the impact of risk factors.
Problems and Countermeasures Analyses of Market-oriented Debt-to-Equity Swaps in China
Authors: Qiao Ziqian
Published: September 2024

In 2016, for the sake of addressing the high leverage of non-financial enterprises and the persistently high number of non-performing loans in commercial banks, the State Council once again proposed market-oriented debt-to-equity swaps. This round of debt-to-equity swaps exhibits distinct characteristics of marketization and legalization and has played a significant role in improving the financial market environment, reducing corporate debt burdens, and achieving deleveraging goals. However, during the implementation process, there are still many practical problems that prevent the fundamental resolution of difficulties. This paper conducts an in-depth analysis of the issues related to market-oriented debt-to-equity swaps and proposes targeted suggestions to establish a more comprehensive institutional framework, aiming for a win-win cooperation among enterprises and banks.
Risk Assessment of Banks and Financial Institutions in China
Authors: Wang Fengpeng
Published: September 2024

In the aftermath of the COVID-19 pandemic, economic development has emerged as a paramount concern globally. Governments, including that of China, have implemented various policies to reignite growth. However, this pursuit of rapid expansion brings with it inherent risks. This study conducts a comprehensive analysis of the risks facing China's domestic banks and financial institutions. It systematically identifies the factors contributing to their vulnerabilities, highlighting the complexities of the economic landscape. The research reveals that external economic conditions, lingering effects of the pandemic, and internal factors such as banks' understanding gaps collectively drive these risks. By illuminating these dynamics, the study aims to enhance understanding of the challenges confronting financial entities. It seeks to provide valuable insights for the comprehensive evaluation of China's domestic financial landscape in the future. Understanding these risks is crucial for policymakers, regulators, and stakeholders in crafting effective strategies to navigate the evolving economic environment. Ultimately, this analysis contributes to a more informed approach towards bolstering the resilience of China's banking and financial sectors amidst ongoing uncertainties.
House Price Prediction Taking Account of the Influence of COVID-19
Authors: Bi Mingyu
Published: September 2024

Machine learning algorithms are utilized in various practical applications and academic research. Due to the advent of digital technology, there is now a greater availability of massive, organized, and georeferenced datasets. This has simplified the use of algorithms for trend analysis and detection as well as forecasting, which helps users make decisions. The purpose of this study is to determine which Machine Learning (ML) algorithms are most effective in projecting housing price and to assess how the COVID-19 has affected these prices. The method includes the stages of data preprocessing, feature manipulation, hyperparameter tuning, evaluation, selection, and, in the end, interpretation of the model. Another objective is to assess and compare several ensemble learning strategies, comprising bagging techniques like random forest, and boosting techniques like Gradient Boosting Regressor, using a linear regression model. The results of this study confirm that the real estate sector is very resistant to pandemics, as the decline in prices was not as severe as initially anticipated. Among the several models that were examined, extreme gradient boosting demonstrated the highest level of accuracy, albeit with a minimal difference.
Kafka caleidoscopio benjaminiano
Authors: Cappa Francesco
Published: September 2024

Benjamin was perhaps Kafka’s most congenial critic, and he was among the first to understand the scope and value of the challenge posed by his entire literary oeuvre. In one of his notes, written in the 1930s, Benjamin placed Baudelaire and Kafka side by side, pointing to the former as a key figure in the literature of the xix century and the latter as that of the xxcentury. The article seeks to show how the main themes of Benjamin’s thought find the ground for elaboration and unraveling in the confrontation with Kafka’s work, opening up a perspective that interweaves the force of criticism with the sometimes visionary view of the most current aesthetic tensions.
USE OF NANOTECHNOLOGY IN CANCER TREATMENT: A REVIEW
Authors: AHMAD MT , NOOR M , HAIDER MU , SHAUKAT H , SALEEM HF , DIN HMU , NASIR NA , RAO MA , KHAN MNUR , TARIQ MB
Published: September 2024

Nanotechnology has become a revolutionary instrument in cancer treatment, providing unparalleled possibilities for boosting drug administration, increasing treatment selectivity, and decreasing systemic toxicity. This review aims to analyze the use of nanoparticles in cancer treatment, explicitly emphasizing drug delivery methods, cancer immunotherapy, and the mitigation of multidrug resistance. This paper aims to thoroughly analyze the main developments in nanoparticle-based therapeutics by synthesizing existing research. Additionally, it will highlight essential deficiencies in the literature, including the restricted clinical use and long-term biocompatibility of these technologies. This study will evaluate research conducted in the last ten years, focusing on recent advancements in nanotechnology, specifically its ability to improve chemotherapy and radiation by leveraging synergistic effects. The investigation will also investigate the obstacles encountered in the field, such as regulatory gaps and safety issues, that hinder the broader implementation of nanotechnology in cancer. Finally, this review will provide valuable perspectives on the future of nanomedicine in cancer therapy, suggesting particular domains for additional studies, such as more rigorous clinical trials and more thorough examinations of nanoparticle interactions within the tumor microenvironment. The results will improve patient outcomes by contributing to the creation of more individualized and efficient cancer treatments.
COMPARISON OF POLYCYSTIC OVARIAN SYNDROME WITH JUNK FOOD CONSUMPTION IN WOMEN OF REPRODUCTIVE AGE IN DISTRICT SIALKOT, PAKISTAN
Authors: SEHAR K , ASHRAF S , RASHEED I , ABBAS A , ABBAS Z , KHAN MR , ASLAM S
Published: September 2024

Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder affecting women of reproductive age, often associated with metabolic and reproductive complications. Junk food consumption has been linked to worsening PCOS symptoms. Limited data from Pakistan exists on this correlation. A study in District Sialkot aims to explore this association. Objective: To explore the correlation between junk food consumption and the prevalence and severity of PCOS symptoms among women of reproductive age in District Sialkot, Pakistan. Methods: This cross-sectional study was conducted at Allama Iqbal Memorial Hospital, Sialkot, from April to May 2024. A total of 80 women aged 18-45 were enrolled, including 40 women diagnosed with PCOS and 40 women without PCOS (control group). Data were collected using a structured questionnaire covering demographic details, medical history, dietary habits, and PCOS-related symptoms. Statistical analysis was performed using chi-square tests and t-tests, with a significance level of p < 0.05. Results: The prevalence of regular junk food consumption was significantly higher in the PCOS group (65%) compared to the control group (5%) (p < 0.001). Women with PCOS who consumed junk food frequently exhibited more severe symptoms, including irregular menstrual cycles (85.7%), hormonal imbalance (78.6%), acne (75%), and hirsutism (67.9%), compared to non-junk food consumers (p < 0.001). Obesity was also more prevalent among the PCOS group (50%) than the control group (30%), though the association between BMI and PCOS was not statistically significant (p = 0.11). Conclusion: This study establishes a significant correlation between junk food consumption and the severity of PCOS symptoms among women in District Sialkot. The findings highlight the need for dietary interventions to mitigate the health burden of PCOS. Further research should explore the role of comprehensive lifestyle modifications, including diet and physical activity, in managing PCOS.
Immunohistochemical Expression of Cyclin D1 in Renal Cell Carcinoma Subtypes
Authors: Al-Omar Zahraa Marwan , Salim Payman Mohammadsalih , Khattab Khalid Wissam Abdulfattah , Abdaljaleel Maram
Published: September 2024

Background: Renal cell carcinoma (RCC) is the second-leading cause of mortality among urological malignancies and accounts for 2–3% of adult malignancies. Approximately 25% of patients experienced recurrence or metastasis subsequent to surgery, accompanied by radiation and chemotherapy failure. Cyclin D1, a critical regulator of the Growth/Synthesis (G1/S) transition, is a subject of significant research. Objectives: To assess the frequency of immunohistochemical expression of cyclin D1 in RCC subtypes and its association with some clinicopathological parameters such as age, gender, size of tumor, histological type, and grade. Methods: During a period of eleven months extending from March 2023 through January 2024, 64 RCC cases were included in this retrospective case series study, obtained from the histopathological departments of private laboratories in Mosul city, Iraq. An immunohistochemistry investigation using Cyclin D1 was performed, and data of the positive cyclin D1 expression were evaluated. Results: The mean age was 54.8 years, with male predominance (53%). Renal cell carcinoma cases included in this study show immunohistochemical expression of Cyclin D1, but with different staining grades. 39% were low expressers, versus 61% were high expressers. Cyclin D1 expression showed a significant association with age, histological type, tumor size, and nuclear grade, respectively. Conclusions: Cyclin D1 is overexpressed in renal cell carcinoma, and targeting it may benefit treatment and prevention. In renal cell cancer, cyclin D1 expression is associated with a favorable prognosis and can aid in predicting patient outcomes.
IMPLEMENTASI ISM CODE KAPAL MV. EASTERN FAIR PADA PT. PELAYARAN MULTI JAYA SAMUDERA BELAWAN
Authors: Sahid Muhammad , Rinaldi Fahmi , Pakpahan Sonya Ledys
Published: September 2024

Pelayaran Multi Jaya Samudera Belawan merupakan Perusahaan yang bergerak dibidang Pelayaran (Shipping) dan Keagenan kapal (Ship’s Agency) yang merupakan anak Perusahaan yang bernaung di bawah PT. Waruna Nusa Sentana GROUP. Makalah ini bertujuan untuk mengetahui Implementasi ISM Code Kapal MV. Eastern Fair Pada PT. Pelayaran Multi Jaya Samudera Belawan. Dalam penulisan makalah ini penulis menggunakan metodologi, selama menjalankan Praktek Darat penulis mengumpulkan bahan – bahan dari metode pengamatan lapangan (Field Study) dan metode pustaka (Library Study) untuk mengetahui lebih dekat bagaimana perusahaan PT. Pelayaran Multi jaya Samudera dalam Implementasi ISM Kapal MV. Eastern Fair. ISM Code adalah sebuah peraturan internasional yang dikembangkan oleh International Maritime Organization (IMO) untuk memastikan keselamatan operasi kapal dan perlindungan lingkungan laut. Dengan mengintegrasikan prinsip-prinsip ISM Code ke dalam operasi mereka, Perusahaan pelayaran dapat menciptakan lingkungan yang lebih aman dan lebih efisien bagi crew kapal maupun di atas kapal, Keselamatan di atas kapal adalah tanggung jawab bersama. Keselamatan merupakan satu bagian penting dalam pengoperasian kapal pada umumnya Diketahui bahwa 80% dari semua kecelakaan disebabkan oleh kesalahan manusia (human error). Kenyataan menunjukkan bahwa 75-80% kesalahan manusia tadi, disebabkan oleh sistem manajemen yang buruk. Semua akan berjalan dengan baik apabila Implementasi ISM Code berjalan dengan baik, Keselamatan dalam hal ini meliputi kapal, Awak Kapal, muatan dan lingkungan alam laut. PT. Pelayaran Multi Jaya Samudera Belawan merupakan perusahaan pelayaran yang mengedepankan pelayanan dan keselamatan sebagai Prioritas utama.
Analisis regresi sederhana hasil pembacaan thermocouple amplifier Adafruit MAX31856
Authors: Efendi Rustam , Padang Welly Liku , Aries Mulhin , Tando Arjal , Herlina Herlina , Nakkir Muh. , Masruhi Masruhi
Published: September 2024

Pengukuran suhu memegang peranan krusial dalam berbagai aplikasi, dari penelitian ilmiah hingga industri. Dalam upaya untuk memastikan akurasi pembacaan suhu, amplifier thermocouple, seperti Adafruit MAX31856, seringkali digunakan. Penelitian ini bertujuan untuk menyelidiki dan menganalisis hasil pembacaan dari amplifier thermocouple Adafruit MAX31856, yang merujuk pada termokopel tipe K yang umum digunakan dalam pengukuran suhu tinggi. Metode analisis regresi linier sederhana digunakan untuk memahami tingkat kesamaan pembacaan dari sepuluh amplifier TC1 hingga TC10 terhadap hasil pembacaan termokopel tipe K. Analisis ini dilakukan dengan bantuan aplikasi MS Office Excel, dan hasilnya sangat menarik. Hasil analisis mengungkapkan bahwa nilai koefisien determinasi (R²) berkisar antara 0,9999 hingga 1, menunjukkan tingkat kesamaan yang sangat tinggi dalam pembacaan amplifier tersebut. Hal ini mengindikasikan konsistensi dan stabilitas pembacaan suhu termokopel tipe K yang dihasilkan oleh amplifier thermocouple Adafruit MAX31856.
Modifikasi sepeda motor honda beat karbu 110 cc menjadi electric vehicle 2 kW
Authors: Nurdin Muh Firdan , Kismanti Shinta Tri , Silalahi Prayoga R.L.
Published: September 2024

Kendaraan listrik saat ini telah banyak digunakan salah satunya adalah kendaraan listrik hasil konversi dari kendaraan motor bakar. Tujuan dari penelitian ini untuk mengetahui proses konversi dan konsumsi daya listrik dari sepeda motor honda beat 110 CC menjadi sepeda motor listrik (electric vehickle) 2 kW. Proses konversi dilakukan dengan mengganti sistem penggerak motor bakar menjadi motor listrik Brush Less Direct Current 2 kW, menambahkan kontroller juken 10 merek bintang racing team, menggunakan baterai GESITS serta memodifikasi sistem transimisi CVT motor bakar. Hasil penelitian menunjukkan konsumsi daya baterai yang dihasilkan pada jalan mendatar sejauh 500 meter pada kecepatan 20, 30, 40 km/jam ialah 0,01, 0,02, dan 0,06 Wh. Sementara konsumsi daya baterai yang dihasilkan pada jalan menanjak sejauh 100 meter pada kecepatan 20, 30, 40 km/jam ialah 0,03, 0,03, dan 0,04 Wh.
Modifikasi rancangan mesin pengupas lada menggunakan software Solidworks
Authors: Aninditya Mas Wisnu , Sayuto Sa’ad Gayu , Suhil Mardison , Prasetia Bagus , Gunawan Pandu , Priyonggo Budi
Published: September 2024

Pada tahun 2019 produksi lada mencapai 93 ribu ton, sedangkan pada tahun 2020 produksi lada di Indonesia sebesar 91 ribu ton. Dibutuhkan waktu sekitar 11-14 hari untuk mengupas lada metode yang digunakan dengan pemeraman atau merendam lada untuk melunakan buah dan dapat mengupas dengan mudah. Tipe mesin lada yang dibuat menggunakan sikat nilon untuk memisahkan kulit dengan biji lada. Tujuan tugas akhir dilakukan untuk menentukan dan menghitung parameter rancangan mesin pengupas lada, melakukan modifikasi rancangan desain mesin pengupas lada, melakukan simulasi desain. Metode pelaksanaan dengan melakukan berbagai identifikasi tentang karakteristik lada dan rancangan mesin sebelumnya, sketsa gambar tangan yang dibuat, menghasilkan gambar desain, dan melakukan simulasi pada desain. Didapat hasil parameter kebundaran lada 0,76, kebulatan lada 1,007, kecepatan putar pulley 840 rpm, nilai torsi 5,08 Nm, kapasitas hopper 9,8L serta derajat kemiringan 55,7o, kapasitas screw 14,24 m3/jam. Hasil gambar berupa part, gambar assembly serta gambar layout dan dilakukan simulasi desain dengan hasil stress analisis, displacement, serta factor of safety.
Pengaruh Komitmen dan Motivasi Kerja terhadap Organizational Citizenship Behavior pada Karyawan PT. Vadhana Internasional Duri
Authors: Simamora Juan Felix Fransiskus , Syahreza Dina Sarah
Published: September 2024

This research aims to determine the influence of commitment and motivation on  of PT. Vadhana Internasional Duri employees. This research uses quantitative methods with a sampling technique using Total Sampling. The population in this study was all 73 employees of the PT. Vadhana Internasional Office. The data collection techniques used were observation and questionnaires. The data analysis technique used is the Multiple Linear Regression Model and Hypothesis testing using the T Test and F Test and Coefficient of Determination, where previously the data had been tested using the Validity Test and Reliability Test. The research results show that Commitment and Motivation have a significant effect on the OCB behavior of PT. Vadhana Internasional employees. Simultaneously, Commitment and Motivation have a significant effect on OCB behavior. The adjusted coefficient of determination (adjusted R2) is 0.0442, which means that the Commitment and Motivation variables contribute to the influence of OCB behavior by 44.2% while the remaining 55.8% is determined by other variables outside this research. This shows that there are still other variables that can explain OCB behavior
Pengaruh Disiplin Kerja dan Kompetensi Terhadap Kinerja Pegawai Melalui Motivasi Kerja Sebagai Variabel Intervening pada Sekretariat Daerah Kota Solok
Authors: Tiareta Isra , Yulasmi Yulasmi , Veri Jhon
Published: September 2024

This study aims to determine the influence of work discipline and competency on employee performance through work motivation as an intervening variable in the Solok City Regional Secretariat. The type of research used is quantitative. The data analysis techniques used were multiple linear regression analysis and path analysis, by circulating a questionnaire of 98 respondents to the state civil apparatus of the Solok City Regional Secretariat, the questionnaire returned 98 respondents. The results were obtained that there was a positive and significant influence of work discipline on work motivation in Solok City Regional Secretariat Employees. There is a positive and significant influence of competence on work motivation in Solok City Regional Secretariat Employees. There is a positive and significant influence of work discipline on employee performance in the Solok City Regional Secretariat Employees. There is a positive and significant influence of competence on employee performance in Solok City Regional Secretariat Employees. There is a positive and insignificant influence of work motivation on employee performance in Solok City Regional Secretariat Employees. Work motivation does not mediate the influence of work discipline on employee performance in Solok City Regional Secretariat Employees. Work motivation does not mediate the influence of competence on functional positions on employee performance in Solok City Regional Secretariat Employees.
Kinerja Pegawai: Lingkungan Kerja, Etos Kerja, dan Disiplin Kerja Melalui Kepuasan Kerja pada Biro Administrasi Pimpinan
Authors: Harefa Roni Putra , Elfiswandi Elfiswandi , Veri Jhon
Published: September 2024

This study aims to see the influence of work environment, work ethic and work discipline on employee performance through job satisfaction as an intervention in the Administrative Bureau of the West Sumatra Provincial Secretariat. The type of research used is quantitative. The population in this study is all employees of the Administrative Bureau of the West Sumatra Provincial Secretariat which totals 50 employees. The sample selection technique uses total sampling and obtained 50 samples. The analysis method uses Structural Equition Modeling (SEM) Analysis with Partial Least Square (PLS). Based on the results of the analysis, it can be concluded that the work environment has a positive and significant effect on job satisfaction. Work ethic has a positive and significant effect on job satisfaction. Work discipline has no effect on job satisfaction. The work environment has a positive and significant effect on employee performance. Work ethic does not have a significant effect on employee performance. Work discipline does not have a significant effect on employee performance. Job satisfaction has a positive and significant effect on employee performance. The work environment has a positive and significant effect on employee performance through job satisfaction. Work ethic has a significant effect on employee performance through job satisfaction. Work discipline does not have a significant effect on employee performance through job satisfaction at the West Sumatra Province Secretariat Leadership Administration Bureau
Analisis Implementasi Pengelolaan Keuangan Desa dalam Alokasi Dana Desa (ADD) Desa Suka Jadi Kecamata Hinai Kabupaten Langkat Tahun 2023
Authors: Kalsum Ummi , Aulia Aulia
Published: September 2024

This study aims to describe and analyze village financial management in the management of Village Fund Allocation in Suka Jadi. The research method used in this study is a qualitative approach with data collection techniques through observation, interviews and documentation. The informants in this study are all Suka So Village Apparatus in 2023 as many as 20 people. The results of the study show that the management of village finances, in this case the Village Fund Allocation (ADD) of Suka Jadi, is the village. The implementation of ADD disbursement in 2023 will be carried out in two stages, the first disbursement will only be partial, namely 60% of the ADD, and the rest will be released in the second stage, which is 40%. The first phase of disbursement of funds will only be realized in January 2023 and the second phase will be realized in July 2023. Meanwhile, the village apparatus honorarium is a routine expense that is paid every month. In the planning stage, procedurally it is in accordance with the regulations, but the target time is not in accordance with the regulations. In the implementation stage, procedurally it is in accordance with regulations even though there is a delay in the disbursement of funds. In the administration stage, it can be said that it is in accordance with the rules. The reporting stage can be said to be on time and in accordance with regulations
Analisis Pengaruh Organizational Citizenship Behaviour (OCB) Terhadap Kinerja Pegawai yang di Mediasi oleh Motivasi di PT. Permodalan Nasional Madani (PNM) Unit Galang
Authors: Sari Vina , Batubara Soulthan Saladin , Insan Muhammad Yalzamul
Published: September 2024

This study aims to examine the influence of Organizational Citizenship Behaviour (OCB) on employee performance mediated by motivation at PT Permodalan Nasional Madani (PNM) Galang Unit. This study uses a quantitative approach. Data was collected through questionnaires that were shared directly with respondents. Data analysis was carried out through the Partial Least Squares Structural Equation Modeling (SEM PLS) method. The results showed that OCB has a significant positive effect on employee performance, and motivation acts as a mediating variable that strengthens the relationship between OCB and performance. These findings indicate that increasing OCB can effectively improve employee performance if supported by high motivation. This research provides insight for company management to focus on developing OCB and motivation to improve employee performance
A Comprehensive Review on Pioneering Nanotechnologies in Advancing Next-Generation Biofuel Production
Authors: P Muthumari , Subbaiyan Naveen
Published: September 2024

Nanotechnology is transforming biofuel manufacturing by enhancing efficiency, yield, and sustainability. This review explores how nanotechnology advances next-generation biofuel production using nanomaterials like catalysts, membranes, and transporters in biomass conversion, fermentation, and purification. Researchers have leveraged the unique properties of nanoparticles to improve reaction kinetics, selectivity, and stability in biofuel production pathways. Nanoscale sensors and monitoring devices provide real-time process control, enabling robust and scalable production. Additionally, innovative Nano biotechnology techniques, such as enzyme immobilization and metabolic engineering, enhance the performance of biofuel-producing microorganisms. This review also focus on challenges like feedstock diversification, energy efficiency, and environmental impact, and suggests that advanced nanotechnologies will revolutionize biofuel production, leading to a more sustainable and renewable energy future.
Major clinical evidence on the use of low-dose naltrexone in the treatment of cancer: a systematic review
Authors: Oliveira Luciene Pereira de , Ferreira Maria Aparecida Orlando de Moraes , Rocha Priscila Mendes Maia , Ricardi Gabriela , Ramos Katia Alves , Telles Cristiane Reis e Lopes , Silva Junior Antonio Carlos da , Silva Ariadne Fonseca Carvalho , Teixeira Thaysa Andressa Brandão Vilela , Moreira Eduardo Vinicius França
Published: September 2024

Introduction: Opioid receptors are groups of receptors (γ-, κ-, δ-, and ζ-opioid receptors) that are widely distributed in nerve cells in the brain, spinal cord, and digestive tract. Naltrexone is a type of general opioid receptor antagonist. It has been used to treat chronic pain syndrome, autoimmune diseases, and cancer at a dose of 5 mg/day, which is generally called low-dose naltrexone (LDN). Objective: It was to analyze the pharmacological functions of low-dose naltrexone, especially in anti-inflammation and immunoregulation, and its therapeutic potential against cancer. Methods: The research and development of the work were carried out from June to July 2024 in the Scopus, PubMed, Science Direct, and Scielo databases, using scientific articles from the last 15 years, following the PRISMA rules. The quality of the studies was based on the GRADE and AMSTAR2 instruments, and the risk of bias was assessed using the Cochrane instrument (Funnel Plot). Results and Conclusion: Fifteen studies were included in the systematic review out of 30. Most studies showed homogeneity in their results, with X2=94.5%>50%. Low-dose naltrexone has immunomodulatory and therapeutic effects. Low-dose naltrexone regulates the production of inflammatory cytokines, influencing the level of endogenous opioid peptides in the body. Furthermore, low-dose naltrexone has an antitumor effect and can modulate the neuroblastoma tumor response, delaying the onset and reducing the incidence rate of tumors, significantly decreasing tumor volume and weight, and DNA synthesis in cancer.
LLM for Differentiable Surface Sampling for Masked Modeling on Point Clouds
Authors: Wang Zeyu , Sun Wenjian , Chu Zong Cheng , Zhang Yiqian , Wu Zhizhong
Published: September 2024

We present MaskPOINT, a novel scheme of masked-wise pretrained models for point cloud self-supervised learning, addressing the challenges posed by 3D understanding, including the ambiguous underlying geometry and irregular topology information. In fact, surface-based geodesic topology pro- vides strong cues for 3D semantic analysis and geometric modeling, but such connectivity information is lost in point clouds and hardly considered. In view of this, we formulate this task into an point sampling problem and man- ifold understanding problem, and develop two techniques, a differentiable topology sampling module and manifold contrastive learning, to enable it. Specifically, the Topology Sampling samples a point cloud into point cloud geodesic field given a query point. Then, the Manifold Understanding enables the point cloud dived into topology strands based on manifold contrastive learning. Then, we randomly mask out some strands of input topology and feed them into the vanilla Transformers. The pre-training objective is to recover the underlying geometry and irregular topology information the masked. We evaluate our pretrained models across several downstream tasks, including point clouds classification, 3D segmentation, few-shot, registra- tion and demonstrate competitive results while representations learned by Mask Point owning strong interpretability.
Deep Tooth LLM: Neural Trajectory Optimization for Tooth Alignment
Authors: Wang Zeyu , Hong Jiaqi , Zhu Ziyi
Published: September 2024

A orthodontic treatment simulation is normally made up of several cycles of treatment, that regularly covers for more than 12 months. Thus, the fundamental determinant in orthodontic treatment is to simulate medically reasonable teeth position in long-term progress. However, existing orthodontic treatment simulation system heavily rely on duplication of efforts from dentists or only estimate final tooth arrangement without orthodontically intermediate procedure. Toward clinically reasonable simulate 3D orthodontic treatment progress, we present DeepOrtho, a deep learning based novel system to simulate medically 3D tooth position for orthodontic treatment planning. Our system takes 3D tooth meshes from patients with malocclusion as input, and sequentially simulates the orthodontically proper 3D rotation and translation for each tooth within the long-term treatment. Notably, we formulate the 3D orthodontic treatment simulation as a reverse process of iteratively denoising teeth arrangements, where DeepOrtho gradually reduces medically uncertain sequences from all the teeth adjustable positions until reaching the desired positions. To the best of our knowledge, we are the first medical simulation system to explore progress 3D orthodontic treatment. Extensive experiments demonstrate that the proposed DeepOrtho outperforms existing solutions in terms of performance and clinical feasibility.
Chế tạo và đánh giá các đặc tính của màng trao đổi ion dựa trên cơ sở màng Nafion
Authors: Dũng Trịnh Việt , Mai Nguyễn Thị Tuyết , Lan Nguyễn Thị , Hoàng Trần Vĩnh , Huệ Đặng Thị Minh , Chính Huỳnh Đăng
Published: September 2024

Thực nghiệm tiến hành chế tạo và đáng giá các đặc tính của màng trao đổi ion dựa trên cơ sở màng Nafion (màng ghép). Các đặc trưng tính chất của màng ghép đã được khảo sát như: phổ FT-IR, phổ NMR, Phân tích nhiệt trọng lượng (TG-DTG), hiển vi điện tử quét (SEM), khả năng trao đổi ion (IEC), tính hấp thụ nước (WU) và độ dẫn điện ion (σ). Kết quả khảo sát xác nhận được việc ghép thành công NaSS và METAC vào các phân tử Nafion. Sự thay đổi hình thái bề mặt của màng Nafion ghép so sánh với bề mặt rất nhẵn của màng Nafion thương mại đối chứng (N212). Các đặc tính hóa lý như khả năng trao đổi ion (IEC), độ hấp thụ nước (WU) cho thấy là được giảm khi lượng NaPSS giảm trong màng ghép. Độ dẫn điện ion (σ) cho khả năng vận chuyển ion của màng sẽ được thay đổi khi điều chỉnh hàm lượng monome trong màng.
Công nghệ gạch thu nước thông minh - tương lai xanh cho cuộc sống đô thị ở Việt Nam
Authors: Phấn Tạ Văn , Sáng Nguyễn Văn
Published: September 2024

Các đô thị ở Việt Nam trong những năm vừa qua, mỗi khi có những trận mưa với lưu lượng lớn thì tình trạng ngập lụt ngày càng nhiều, ảnh hưởng nghiêm trọng tới môi trường và hoạt động của người dân. Cần có các giải pháp kết cấu mặt đường có khả năng thoát nước bề mặt để giảm ngập lụt, ô nhiễm môi trường và tăng mực nước ngầm cho đô thị là điều rất cần thiết cho các đô thị ở Việt Nam.
Hiện nay trên thế giới đã có những sản phẩm Gạch bê tông thấm nước hay còn gọi là bê tông thoát nước nói chung, gạch tự chèn thấm nước nói riêng đã được nhiều nước trên thế giới sản xuất và sử dụng từ hàng chục năm về trước. Tuy nhiên sản phẩm này hiện có các nhược điểm về khả năng tiêu thoát nước, độ bền sản phẩm do quá trình thủy hóa vật liệu khi nước ngấm qua và tình trạng bão hòa nền đất phía dưới làm giảm khả năng chịu lực của nền đất. Gạch thu nước thông minh kết hợp tiêu nước qua hố giếng không ảnh hưởng tới cốt nền đường là giải pháp khắc phục được hoàn toàn các nhược điểm đó.
Strengthening The Role Of Christian Family Education For The Faith Development Of Correctional Inmates In Correctional Institution
Authors: Rantung Djoys A. , Jura Demsy , Vandiano Vardik
Published: September 2024

Faith development is something very important in a person's life because through it, the level of spiritual maturity can be seen, which can have a positive influence on the life of every individual without exception. On that basis, the research title "Strengthening the Role of Christian Family Education for the Faith Development of Correctional Inmates in Correctional Institution" becomes something important to study. This research highlights the importance of the family's role in participating through Christian family education in the faith development of its family members who are inmates in a correctional institution. This qualitative research, utilizing a literature review approach, is intended to be a reference for families with members who are inmates in a correctional institution. It aims to encourage these families to participate through Christian family education in nurturing their members so that when the time comes for them to be released from the correctional institution, they are ready to live life as members of society in general.
Контент-маркетинг у цифровому брендингу
Authors: Пономаренко І. В. , Ягельська К. Ю.
Published: September 2024

У статті узагальнено сучасний досвід стосовно особливостей використання контент-маркетингу у цифровому брендингу у відповідності з наявними тенденціями розвитку взаємовідносин між компаніями та користувачами в Інтернеті та передовими інформаційними технологіями, які дозволяють підвищувати ефективність бізнес-процесів. Розкрито передумови використання контент-маркетингу сучасними компаніями для забезпечення ефективних та довгострокових комунікацій з користувачами в цифровому середовищі. Обґрунтовано орієнтацію на створення тематичного контенту для представників поколінь Y, Z та Альфа як основних клієнтів в Інтернеті. Представлено основні види контенту (фото, відео, текст, аудіо), які використовуються компаніями для взаємодії з цільовою аудиторією та стимулювання попиту на відповідні товари і послуги. Доведено доцільність використання релевантного контенту для комунікацій з цільовою аудиторією, оскільки в цифровому середовищі наявність істотної конкуренції між компаніями призводить до генерування великої кількості тематичних матеріалів, серед яких користувачі обирають найкраще. Розкрито перспективність розвитку ринку контенту у зв’язку зі зростанням чисельності цільової аудиторії та перспективності взаємодії компаній зі споживачами завдяки застосуванню тематичного контенту. Представлено фактичні та прогнозні значення доходу від контент-маркетингу у світі з 2018 по 2026 рр. Наведено розподіл компаній за питомою вагою бюджету, що витрачають на контент-маркетинг у 2024 р. Доведено доцільність застосування контент-плану для розповсюдження контенту на різноманітних ресурсах в Інтернеті, що дозволяє здійснювати комунікації з певними групами споживачів в оптимальний час. Наведено концептуальну схему реалізації стратегії контент-маркетингу на основі використання різноманітних цифрових інструментів. Доведено доцільність генерування контенту у відповідності з принципами креативності. Обґрунтовано доцільність застосування різноманітних інструментів цифрового маркетингу для розповсюдження релевантного контенту, що дозволяє максимізувати охоплення цільової аудиторії. Розкрито специфіку використання цифрового брендингу в сучасних умовах. Наведено основні елементи цифрового брендингу, які дозволяють компаніями створювати позитивне враження серед користувачів та виділятись порівняно з іншими учасниками ринку.
Youth Speaks Up: Perceived Communication Changes Experienced by Grade 6 Participants in a Personal Development Program
Authors: Brann-Barrett M. Tanya
Published: September 2024

A nine-month program entitled Youth Speaks Up is delivered annually to grade 6 students from Sydney, Nova Scotia. One goal of the program is to provide an opportunity for the development of positive communication skills in participants. The purpose of this project was to determine if students participating in the program perceived changes in their communication ability and comfort level as a result of participation in the program. Qualitative focus groups were conducted, and responses suggest that many participants experienced positive changes in their communication comfort levels in public and interpersonal communication contexts, and specifically in their ability and willingness to express their ideas. Participants believed factors such as consistent practice and interaction with new people influenced the changes. Students’ recommendations for program development are also presented.
El contexto socio-cultural de la obra de Chejov
Authors: Luna Pérez Kevin Andres , Pérez Latorre Fanny Genoveba
Published: September 2024

El texto analiza la influencia de Antón Chéjov en la dramaturgia universal, destacándolo por encima de otros autores rusos como Gógol, Pushkin o Dostoyevski, y subrayando la necesidad de comprender primero sus logros filosóficos y psicoanalíticos antes de hacer comparaciones con otros dramaturgos. Chéjov, como maestro del naturalismo, retrató la banalidad de la vida cotidiana y la frustración de los personajes, alejándose de la sátira clásica y explorando la tragedia humana derivada de deseos inalcanzables y presiones familiares, lo que ha influido en cineastas contemporáneos como Nuri Bilge Ceylan, Lucrecia Martel y Yorgos Lanthimos. Su obra rompe con la tradición dramática occidental, presentando una crítica a la burguesía moscovita a través de personajes que enfrentan crisis internas y deseos no cumplidos, diferenciándose de autores como Émile Zolá en su capacidad para mostrar la complejidad emocional y la desolación. Además, el texto examina la relación entre Chéjov e Iván Turguénev, quien influyó indirectamente en su estilo afrancesado de la narrativa rusa, destacando que, aunque no hay evidencia clara de que Chéjov fuera un lector de Turguénev, existe una afinidad estética entre ambos que llevó a Chéjov a elevar el naturalismo a nuevas alturas.
Diseño de un Dashboard basado en un sistema de incidencias técnicas reportadas en una caja de ahorro y crédito
Authors: Castillo Pinto Raúl Ovidio , Calsina Condori Helarf Ferrer , Mamani Paredes Javier
Published: September 2024

En el estudio se diseñó un dashboard para la optimización de toma de decisiones sobre incidencias técnicas en el área de soporte de ahorro y crédito, alineado con la visión organizacional y múltiples perspectivas. Se adoptó la metodología de Programación Extrema (XP) y patrones Data Access y Business Object con MySQL, seleccionando trece usuarios mediante un muestreo por conveniencia para la evaluación del sistema, y se recopilaron datos a través de encuestas y observación directa. Los resultados muestran que el sistema tiene confiabilidad (61.54%), usabilidad (53.58%) respuesta en tiempo de ejecución (61.54%), reducción de costos de operación (84.62 %) y mejora de control (92.31%) y esto mejora la gestión de información y la toma de decisiones sobre mantenimientos, permitiendo un control eficiente de los procesos, reduciendo tiempo y costos, aumentando la productividad. Los usuarios calificaron el sistema como excelente, mejora del 92% en la gestión de información. El dashboard desarrollado satisfizo las necesidades, resolvió los problemas identificados por los usuarios e incrementó la flexibilidad y rapidez en las operaciones. La implementación del dashboard de sistema integral demostró una herramienta valiosa para el área de soporte, proporcionando beneficios tangibles para la organización y la gestión de contribuyendo significativamente a la optimización de incidencias técnicas.
ANALISIS DATA PELANGGARAN LALU LINTAS DI PERSIMPANGAN KOTA BANDUNG : STUDI KASUS JALAN RAYA SOEKARNO HATTA
Authors: Muhamad Hadziq Ilham  , Rosmawati  , Fitrah Rumaisa
Published: September 2024

Paper ini bertujuan untuk menganalisis data pelanggaran lalu lintas dengan menggunakan pendekatan kuantitatif. Populasi penelitian adalah seluruh pengendara kendaraan bermotor yang melintas di kota Bandung selama periode waktu tertentu. Sampel penelitian diambil dengan metode purposive sampling, yaitu pengendara kendaraan bermotor yang tercatat melakukan pelanggaran lalu lintas di persipangan sepanjang jalan raya Soekarno Hatta. Instrumen penelitian yang digunakan adalah rekaman dari cctv ATCS Dishub Bandung.
Data yang diperoleh dianalisis dengan menggunakan metode statistik deskriptif. Hasil analisis deskriptif menunjukkan bahwa pelanggaran lalu lintas yang terjadi pada persimpangan sepanjang jalan raya Soekarno Hatta mengalami kenaikan seiring bertambahnya volume jumlah kendaraan di Indonesia khususnya di kota Bandung.
Berdasarkan hasil penelitian ini, disarankan untuk meningkatkan pengawasan dan penegakan hukum terhadap pelanggar lalu lintas yang melakukan pelanggaran yang paling sering terjadi. Selain itu, perlu adanya upaya pencegahan dan pengurangan faktor risiko yang mempengaruhi perilaku pelanggaran lalu lintas, seperti memberikan edukasi tentang keselamatan berkendara dan meningkatkan kualitas infrastruktur jalan raya.
SISTEM KEAMANAN JARINGAN DALAM UJIAN ONLINE SMK IPIEMS SURABAYA MENGGUNAKAN METODE ALGORITMA ADVANCED ENCRYPTION STANDARD (AES)
Authors: Primatama Muhammad Aldito Primatama , Jenny Arista  , Mochammad Naufal Haqayari  , Hosniyah  , Sigit Perdana  , Muhlis Tahir
Published: September 2024

Di zaman modern ini, di mana Industri 4.0 telah menjadi bagian dari perkembangan zaman, penggunaan teknologi semakin berkembang dengan cepat di berbagai sektor, termasuk kesehatan, militer, dan pendidikan. Dalam bidang pendidikan, ujian online telah menjadi salah satu media pembelajaran yang populer. Namun, meskipun ujian online ini praktis, masih ada celah keamanan yang perlu diperhatikan. Dari celah tersebut maka diperlukan sistem ujian online yang memiliki fitur keamanan yang efektif dan akurat. Salah satu cara untuk mengatasi celah keamanan ini adalah dengan menggunakan salah satu metode enskripsi yang saat ini banyak digunakan, yaitu Advanced Encryption Standard (AES). Berdasarkan hasil penelitian tersebut, terungkap bahwa penggunaan metode enkripsi AES bisa digunakan untuk mengamankan data-data penting dalam ujian online, seperti kata sandi, pertanyaan, dan jawaban. Proses enkripsi dilakukan dengan mengubah teks biasa menjadi nilai hash menggunakan kunci pribadi (private key), sehingga menghasilkan teks bersandi (ciphertext).
PENGEMBANGAN APLIKASI PELAPORAN KERUSAKAN BERBASIS ANDROID UNTUK PT KAYU MULTIGUNA INDONESIA DENGAN METODE RAD
Authors: Majid Ardian , Dwi bhakti Henny
Published: September 2024

This research aims to address the issues of ineffective damage reporting at PT Kayu Multiguna Indonesia. These issues include delayed reporting and equipment failures that are not promptly resolved. The objective of this research is to develop an Android-based application using the Rapid Application Development (RAD) methodology to facilitate and expedite damage reporting while enabling better monitoring. The development process involves requirement analysis, visual user interface design, application development, as well as testing and continuous improvement. The result is an Android damage reporting application that allows employees to quickly report damages, reduce incident response times, and track repair statuses through the application. This application is expected to enhance the operational efficiency of PT Kayu Multiguna Indonesia by integrating Android technology and RAD methodology. The discussion covers the advantages and disadvantages of the application, as well as potential future improvements and developments. In conclusion, the Android-based damage reporting application developed with the RAD methodology successfully addresses the issues of inefficiency in reporting at PT Kayu Multiguna Indonesia. Suggestions for further development include enhancing the application's functionality, such as reporting with images or maps, and considering integration with the company's asset management system. This application is expected to assist PT Kayu Multiguna Indonesia in improving operational efficiency, accountability, and productivity in handling damages.