bluuebunny/crossref_metadata_2025 huggingface dataset:
Importance of Ayurvedic Dinacharya in Geriatric Care: A Review Study
Authors: KM Shalinee
Published: January 2024

Natural and healthy ageing is the main aim of the health science. Because the number and proportion of people aged 60 years and older in the population is increasing. The number of people aged 60 years and older was 1 billion. This number will increase to 1.4 billion by 2030 and 2.1 billion by 2050. This increase is occurring at an unprecedented pace and will accelerate in coming decades, particularly in developing countries. After 60 Years of age persons mainly compromised with following health conditions like hearing loss, Cataracts and refractive errors, back and neck pain, osteoarthritis, chronic obstructive pulmonary disease (COPD), diabetes/HTN/cardiac disorder, urine incontinence, depression and dementia. Aims and Objective of this review study is to establish the importance of healthy life style Dinacharya like Malautsarjana, Dantadhawana, Anjana Kriya, Nasya, Karnapurana, Padhabhyanaga and Sirobhyanga, Abhyanga, Vyayama etc. for slow and healthy ageing. As material & methods Classical textbooks, study of WHO website, different databases were used. Study were concluded as regular follow of Dinacharya (daily schedule), decreases the health care and financial burden of the world by slow down the ageing process and maintain the healthy aging.
Role of Noni (Morinda Citrifolia) in Dentistry
Authors: D Saravanan
Published: January 2024

For many centuries herbal products were used in Indian traditional medicine for treating a variety of ailments. One such herb was Noni, which was favoured by many physicians because of its excellent healing properties. In this time and age many native medicine has been long forgotten because of modernisation in western medicine and lack of knowledge in traditional medicine. For the last few decades many physicians and modern day researchers have extended their knowledge and researches among these century old healing methods because of their increased medicinal importance with lesser known side effects, economical highly effective to achieve a healthy state. Even though Noni has been commonly used as a health drink supplement and various parts of the plants were used in day to day life, its definite role in dentistry remains unknown. This review explains about the various methods in which Noni has been used in dentistry to treat oral infections.
The Anti-Viral Potential of Medicinal Plants and Herbal Formulations for the Treatment of Dengue Fever
Authors: S Ugariogu
Published: January 2024

From the existence of human civilization, medicinal plants and herbs have been used for various purposes all over the world. Some of the plants with medicinal activities have played crucial roles in the management of the health care system. Nowadays, dengue fever has become a major concern for governments and the world health organization due to its mortality and morbidity in tropical and sub-tropic regions. The need for therapeutic plants for the treatment of Dengue fever is more urgent compared to the past. In past, medicinal plants have been used due to their therapeutic activity for the treatment of vector-borne diseases such as Malaria. Demand for natural medicine is increasing due to its best efficacy and safety. Additionally, natural medicines are also cost-effective as compared to synthetic medicines. This review aims to describe the medicinal plants distributed all over the world with the best therapeutic potential for the treatment of this ailment. Furthermore, pathogenesis, characteristics of a disease, and prevalence are also described in this review. It has been demonstrated from recent and current studies that natural medicine and plants having medicinal activities are considered safe and better treatments for all diseases.
A Review Article on Samprapti-Vighatana of Manyastambha (Cervical Spondylosis) by Panchakarma Therapy
Authors: H Singh
Published: January 2024

Cervical Spondylosis is a degenerative condition of the cervical spine that causes pain, stiffness, and tingling sensations radiating from the shoulder to the digits along the course of the nerve, indicating nerve root compression. Loss of curvature, reduction of disk space, osteophytes formation these are main anatomical changes associated with cervical spondylosis that is a common spinal problem nowadays. Cervical spondylosis affects approximately 95% of people by the age of 65, and it is the most common spine dysfunction in the elderly. but occupational trauma is increasing its prevalence in young and middleaged people. According to their symptoms, cervical spondylosis is co-related with Manyastambha in Ayurvedic perspective. Manyastambha is one of the Vata Vyadhis mentioned in Vata Nanatmaja Vyadhi. According to Sushruta Nidana Sthana the Vata covered by Kapha is caused by day sleep, sitting and standing (in fixed position), and constantly gazing upward these are some of the important Nidans of Manyastambha. Ruka and Stambha (pain and stiffness) are the sign and symptoms mentioned in our text. Abhyanga, other Ayurvedic treatments, particularly Panchakarma, can aid in successful management.
An Economic Analysis of Medicinal Herb Colocasia for Leaf Production
Authors: G Devi
Published: January 2024

Objective: To study the level of input use in colocasia production, estimate the cost and return and disposable pattern. Colocasia herb is rich source of phenols, flavonoids, saponins, tannins, glycosides, sterols and triterpenoids, therefore, used as traditional medicaments. Farmers cultivate this multi cut crop only for leaf production in middle Gujarat. Methods: This leafy crop production mainly depends upon the level of input used. Hence, the use of judicious inputs (nutritional and irrigation) in production process is vital in this multi cut crop cultivation. Results: Average gross return (Rs. 486454.45 ha-1) and net return (Rs. 293452.22 ha-1) were obtained by producers. Price received by farmers at field level was Rs. 2309.20 q-1 and the cost of production (Rs./q) of colocasia was the tune of Rs. 1020.20. This indicated that price received by producers was higher as compared to the cost incurred by them. The total marketing cost incurred by all the middlemen in the identified channel was about Rs. 844.77 q-1. Out of which the highest cost was incurred by village trader followed by retailer, wholesaler cum commission agent and farmer. Average total margin earned by different functionaries was Rs. 3969.39 q-1 and the margin was higher at retailers’ level (Rs. 2182.50 q-1) as compared to village trader (Rs. 1245.23) and wholesaler-cum-commission agents (Rs 541.66 q-1). The producer’s share in consumer’s rupee was quite low (32.35 per cent) and the price spread was Rs. 4814.16 q-1 in the identified marketing channel of colocasia in study area. Conclusion: Overall, colocasia is the remunerative crop for the farmers and needs to shorten the marketing channel.
The Health of Women Living in Rural Settlements: The Women of the Mandacaru Settlement
Authors: Lima Erika Carolina Fernandes
Published: January 2024

The health of women living in rural settlements in Brazil goes through a diversity of situations that requires intensity and dedication, as it goes through the struggle for land, housing, survival. These women struggle for space, autonomy, work, and their health care practices are strongly aligned with these processes. Thus, the objective of this research was to understand how these women live in the Mandacaru Settlement and the relationship between their experiences and life experiences and health. This is a qualitative research with ethnographic approach through immersion in the field and using the technique of participant observation. The analyses were performed from the interpretative analysis. These women seek to carry out their care practices within a logic that permeates work, the struggle for land and autonomy as women farmers and rural workers.
Occupational Sun Exposure in Agents Fighting Endemics in the Municipality of Ourinhos-SP
Authors: Machado Diego Gimenez
Published: January 2024

Introduction: The skin, which represents the largest organ in the human body and makes up around 16% of body weight, plays a fundamental role in protecting the body's internal structures against the external environment. It is structured into three distinct layers: the epidermis, the dermis and the hypodermis (also known as the subcutaneous tissue). This organ has several purposes for the functioning of our body, such as: perspiration, thermoregulation, pigmentation, nutrition, and mainly protection against harmful agents. The objective of this present study was to analyze occupational sun exposure in agents fighting endemic diseases in the municipality of Ourinhos-SP. Method: The research was carried out using a questionnaire on sun exposure and photoprotection, containing 11 questions regarding photoprotection and sun exposure habits, applied to 27 (twenty-seven) agents combating endemic vector diseases, in Ourinhos-SP. Results: 44% of participants expose themselves to the sun for more than 6 hours from Monday to Friday and on weekends this exposure decreases to 7.6%, exposure to the sun in summer 65.2% of participants expose themselves to the sun between 10 am and 3 pm and 44.4 of the participants do not use sunscreen daily. Conclusion: It is concluded that these professionals face a high risk of developing skin cancer.
The Importance of Health Management in Developing Countries; Choosing a Health Champion or a Slaughterhouse Executioner
Authors: Akhondzardaini Razieh
Published: January 2024

Within an age wherein human wellness and uplifting resilience’s quality wield matchless import, healthcare administrators epitomize a pivotal and weighty part inside community. They prove accountable for guiding and managing medical infrastructure and amenities, whereby they must employ extraordinary faculties and skills to advance and refine health infrastructures.
Emphasizing Health Literacy in Nursing Education: Equipping Nursing Students with Literacy Skills to Improve Patient Outcomes
Authors: Lopez Michele Lucille
Published: January 2024

Nine out of 10 adults in the United States are said to have low health literacy skills. In a national Danish study, four out of ten adults were found to have problems addressing complex health issues. Factors associated with low health literacy include advanced age, diverse cultural backgrounds, marital status, low socioeconomic class, and limited education. Low health literacy skills contribute to negative patient outcomes which include increased morbidity and mortality. They are economical and societal consequences for poor health literacy. There is also increased burden on the United States healthcare system as low health literacy adds additional $106-$238 billion costs to health care systems. Health professionals should be alert to the warning signs of low health literacy in at risk populations. Nursing academia is perfectly positioned to proactively address health literacy levels by incorporating creative lesson plans into the undergraduate curriculum.
The Surprising Connections between Oral Health & Well Being! Routine Oral Checks- A missed Opportunity for Dental, Oral & Overall, Health!
Authors: Kishanrao Suresh
Published: January 2024

Our teeth don't necessarily hurt until something big is going on. While some health issues show up in the mouth, Poor oral hygiene can lead to negative health outcomes, the problems go both ways: Some studies show that there may even be a connection between poor oral health and worse brain health Brushing at least twice a day, flossing at least once a day, contribute to greater dental, oral and overall health." Studies suggest that oral bacteria and the inflammation associated with a severe form of gum disease (periodontitis) play a role in diseases like oral thrush, loose teeth, carries. Similarly, diseases such as diabetes and HIV/AIDS lower the body's resistance to infection, turning oral health problems more severe. A primary care doctor plays varied roles – a scientist, a healer, and an organized service provider. Healing may not reverse the damage but curtails the illness or its consequences from controlling our lives. Every PCP as they grow into the profession must be driven by competence, newer medical developments & technologies, precision in decision-making / treatment, improving people’s lives, understanding the importance of compassion, and realizing that the science is incomplete, then only a healer emerges in him or her. The system must take responsibility for their appropriate training. Each PCP must make it a practice to have a quick scan of the mouth in every visit of their patients not to miss early detection, treatment, and preventive care opportunity. Materials and Methods: This article is based on identification of two cases of Oral cancers one in early stage, biopsied leading to simple excision and cured from Bhutan and another case from Raichur in November 2023 in late stage currently under chemotherapy, one case of Aphthous ulcer and a few cases of gingivitis due to diabetes, with mixed results.
Characterization of Libyan Cobra (Naja haje) Venom using Fluorescence and UV-Visible Spectroscopy
Authors: AM Gbaj
Published: January 2024

Snake venoms act as a preparative to defend animals against predators and helps in immobilizing and digestion of prey. Venoms consist of a combination of enzymes and toxins, such as metalloproteases, phospholipase A2, L-amino acid oxidase and toxins, including cytotoxins and neurotoxins. In addition to their toxicity, venom components exhibit several pharmacological activities and can be used as templates for drug design. The Libyan cobra venom was studied using UV-visible and fluorescence spectroscopic techniques. The cobra protein main chain absorbs light in the region of 240-340nm. The aromatic side-chains of cobra venom contain tyrosine, tryptophan and phenylalanine which are responsible for the absorbance in this region. Cobra venom provides intrinsic fluorescence emissions due to excitation of tryptophan residues, with some contribution from phenylalanine and tyrosine emissions. In addition, disulphide bridges contribute considerable absorption in this wavelength range. The main fluorescence obtained is due to tryptophan which has a wavelength of maximum absorption at 280 nm and an emission peak ranging from 310 to 350 nm. UV-visible absorption and fluorescence spectroscopic techniques are sensitive and rapid to study cobra venom in order to better comprehend the performance of this venom.
Utilization of Tandem Oxyanionic Cyclization/Claisen Rearrangement Strategies for the Construction of Seven and Eight-Membered Carbocyclic Ring Systems
Authors: TV Ovaska
Published: January 2024

This article describes the development of microwave-assisted oxyanionic 5-exo-dig cyclization-Claisen rearrangement sequence as a convenient “one-pot” route to a variety of seven- and eight membered carbocyclic ring systems. This process was used as the key transformation for the construction of several natural products, including frondosins A, B, and C.
Selected Examples of the Metal-Free Synthesis of Allenes (2017 – 2023)
Authors: BL Walker
Published: January 2024

Although metal catalysts are widely used in chemical reactions, there are certain limitations and concerns associated with their use in medicinal chemistry. Many of the metal catalysts used in pharmaceutical production can remain in the final product and be toxic to human health. These impurities might not be easily removed and could negatively impact the quality of the final product. Metal catalysis can also require harsh conditions, such as high temperature and pressure, which can lead to the degradation of sensitive compounds. Furthermore, metal catalysts are from finite resources and their use can have significant environmental impacts. While metal catalysts have their place in organic synthesis, especially in industries outside of pharmaceuticals, the stringent requirements for safety and purity make them less than ideal. This minireview explores some of the latest metal-free methods for the preparation of the highly versatile fictional group, allenes. The methods described within are suitable metal free methods to prepare cumulated dienes which could be used in the production of complex therapeutics.
The Economic Importance of Insects: A Comprehensive Review
Authors: L Shirani-Bidabadi
Published: January 2024

Insects are regarded as the largest group of arthropods on earth. They are easy to breed and have a large population due to their high fecundity and species diversity. Though a lot of people are aware of honey and silk as products from beneficial insects, many people are also unaware of other products like wax, Lac, gall aphid and their uses. Insect breeding and their industrial uses have attracted much attention in different countries across the world. Insects are often reared for the biological control of agricultural and sanitary pests. Some other insects serve as chemical raw materials for industries. In agriculture, insects are used as pollinators and to increase the yield of crops Scorpion venom and oily substances from blister beetles and other insects are used as medicine. In this comprehensive review article, we have fully examined the use of insects in the industry.
Extraction of Lawsone Active from the Henna Leaves (Lawsonia Inermis) by Solvent Extraction Method
Authors: Sankar Jayaganesh
Published: January 2024

Natural hair colour technology recent days very much pronounced by the consumer due to the awareness about the carcinogenic problem of synthetic dyes. Natural hair colour or dyes are safe to use, it does not harm to the hair, does not bleach. Among the various natural hair colour technique, the henna hair colour is very much pronounced in south Asia, since the material readily available for colouring. In this present attempt to aim to identify the potential solvent for the extraction and make the stable format of extracted lawsone for the hair colour application. Present study results immense useful to the personal care industry to derive the suitable extraction plan for the lawsone and helps to make the product to address the regular consumer pain point area especially the henna paste preparation and colour delivery. The pure henna powder was collected from high crop season from Rajasthan Henna growing garden in India and tested the initial lawsone content through HPLC assay. Sigma Aldrich standard 2-hydroxy-1,4 naphthoquinones act as a reference standard. Lawsone from the leaves are extracted by using the organic solvents like toluene, ethyl acetate, diethyl ether, Carbon tetrachloride, isopropyl acetate, n-Hexane and chloroform. Crude extract yield was higher in ethyl acetate solvent extraction followed by diethyl ether and toluene, and it was lower in n-hexane solvent extractions. Among the purity of lawsone was higher in chloroform i.e., 80% purity and followed by carbon tetra chloride (76%) and toluene (75%); among the studied solvent the ethyl acetate shows the less purity i.e. 32% of lawsone. Polarity index directly and positively correlated with yield and lawsone recovery percentage. Ninhydrin test also shows the negative for the solvent extracted lawsone, however it shows the positive for the water extraction. Overall study clearly indicates that the solvent extraction of lawsone molecules from henna leaves delivers the vibrant colour delivery when compared to the regular consumer practices. Overall experiments are confirming that the absence of amino groups helps to maintain the shelf life of the products. Overall study clearly indicates that the toluene extraction of lawsone is beneficial with respect to the cost, yield and performance of the hair swatches. Findings of solvent extractant of lawsone immense useful to make the traditional shade in convenient way.
Acral Peeling Skin Disease: About 2 Cases
Authors: Houssaini Asmaa Sqalli
Published: January 2024

Acral peeling skin syndrome is a rare, autosomal, recessive genodermatosis characterized by painless spontaneous exfoliation of the skin of the hands and feet at a subcorneal or intracorneal level. We are reporting 2 cases of spontaneous asymptomatic peeling skin limited to the acral surfaces especially the soles of the feet. Skin biopsy showed slight separation between the granular and corneal layers, with no inflammation. Both of them were treated with emollient and a slight improvement has been noticed
Fibromyalgia as a Localized Non-Length-Dependent Small Fiber Neuropathy, Responding to Topical Phenytoin
Authors: Hesselink JM Keppel
Published: January 2024

A number of fibromyalgia patients were treated by prescribing a topical analgesic treatment based on phenytoin cream. This often resulted in clinical relevant pain reduction and increased quality of life. One explanation of this phenomenon could be that these patients are not suffering from fibromyalgia in a classic sense. In reality they might suffer from localized non-length-dependent small fiber neuropathy (NLDSFN). Recent studies suggest a prevalence of small fiber pathology in around 50% of all fibromyalgia patients. This would imply that half of all patients suffering from fibromyalgia might profit from a topical treatment based on the broad acting sodium channel blocker phenytoin.
DYRK1A (Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A), a Master Regulatory Protein Involved in Down Syndrome Clinical Neurological Abnormalities and Associated Mental Retardation and a Promising Potential Drug Target for Therapeutics and Treatments
Authors: M Rachidi
Published: January 2024

Over-expression of chromosome 21 genes, particularly in Down Syndrome Critical Region (DSCR), is the main cause of Down syndrome (DS) neuropathological features including mental retardation, cognitive impairments and early onset of Alzheimer’s disease. One of DSCR genes, that we studied herein, DYRK1A (Dual-Specificity Tyrosine-Phosphorylation-Regulated Kinase 1A), is a master regulatory protein involved in DS neuropathological features and associated mental retardation. Interestingly, normalization of DYRK1A over-expression by DYRK1A inhibitor, epigalloctechin-3-gallate (EGCG), rescues brain defects, restores cognitive impairments in DS trisomic and DYRK1A transgenic mouse models and in DS patients. These results indicates DYRK1A inhibitor epigalloctechin-3-gallate (EGCG) as an effective treatment and DYRK1A as a key regulatory protein involved in DS clinical neuropathological features suggesting DYRK1A as a valuable potential drug target for therapeutics and Treatments of DS and mental retardation opening new directions for developing new medical preventive and therapeutic treatments.
Incredible Clinical Causes beyond a Five-Month-Old Boy's Poor Feeding Include His Rapid Brain Cognition and Preference for Certain Colors As Well As His Early Experience with Those Colors: Case Report
Authors: KSY Qazaryan
Published: January 2024

The study's abstract highlights the numerous clinical factors that contribute to a five-month- old boy's malnutrition in addition to inadequate feeding. These factors include color choice, early color vision, and mature brain cognition. Infants normally develop their sense of perception during their first year of life. This article emphasizes how a five-month-old baby can recognize colors, in particular red and blue ones. I also go through how, in very rare instances, the early development of color perception can have a clinical effect on feeding. This essay questions the widely held belief that babies under six months old can only recognize the colors white and black. This article presents the clinical data-based evidence that a child can distinguish between the colors red and blue at the age of five months and how, due to his abnormally advanced brain cognition and color perception development, he may determine for himself which color to choose. This article looks at how infants' perceptions of color are unrestricted in terms of knowing which color they choose to feel at ease with during feeding. This clinical example can help you better understand how children learn to recognize and perceive color. This article paves the way for future clinical studies on color perception and the early brain development of cognition.
Inter-Relationship between Conceptual Ambiguity and Naming Performance in Persons with Aphasia
Authors: AB Panchakshari
Published: January 2024

Aphasia is an acquired language disorder with a wide variety of symptoms. Anomia or word finding difficulty is a common symptom of aphasia regardless of the type of Aphasia. Conventionally a wide variety of confrontation naming tests are used to assess the naming domain in Aphasia. However the confrontation naming test is deemed to be simple limiting its utility. The current study uses fusion pictures which are conceptually loaded. The developed test was administered on 8 persons with aphasia and 0 neuro-typical adults. Both between and within group analysis revealed a significant difference. Persons with aphasia exhibited more difficulty on fusion compared to non-fusion pictures unveiling the role of conceptual ambiguity in naming.
Small Bowel Perforation at the Duodeno-Jejunal Junction from a Migrated Biliary Stent: A Case Report
Authors: AA Mohamed
Published: January 2024

Background: The most common sites of reported bowel perforation secondary to migrated biliary stents were duodenal or colonic. However, small bowel perforations were reported in a few cases. Herein we present a case of small bowel perforation secondary to migrated biliary plastic stent at the duodeno-jejunal junction (DJ). We think this peculiar site is the first to be reported as a perforation site secondary to migrated biliary stent. Case Presentation: We present the case of female Egyptian patient with severe abdominal pain and air under diaphragm after Endoscopic Retrograde Cholangiopancreatography (ERCP) for Klatskin tumor. The patient underwent a midline laparotomy. A moderate collection of enteric fluid was encountered with migrated stent causing perforation of the small intestine at DJ. The stent was removed, and primary closure was done. The patient could not be extubated due to bad chest condition and admitted to ICU for 48 hours then extubated after improvement of the chest condition and ability of the patient to maintain good oxygen saturation in room air. Unfortunately, the patient developed massive pulmonary embolism on the fifth postoperative day and died. Conclusion: Suspicion of stent migration should be put in mind in any patient presented with abdominal pain with history of previous ERCP and biliary stenting. Endoscopic removal and mucosal repair are possible in select cases. This is still not available for DJ or small bowel. Further research and future innovations may overcome this challenge.
Astronomy and Space Science: The Key to Future Economy and Politics
Authors: Chandra Swarniv
Published: January 2024

Astronomy and space physics play a pivotal role in our quest to understand the universe and its fundamental laws. These fields are the gateway to unlocking the mysteries of the cosmos. Astronomy reveals the origins of celestial bodies, helping us comprehend the birth and evolution of stars, planets, and galaxies. It also aids in tracking potentially hazardous space objects that could threaten our planet. Space physics delves into the fundamental forces and particles governing the cosmos, shedding light on cosmic phenomena like solar flares and cosmic rays.
Modified Gravitation and Mach's Principle: An Alternative to the Dark Matter and Dark Energy Cosmological Paradigm
Authors: Falcon Nelson
Published: January 2024

The general approach is that all particles with non-null rest mass are subject to the force of gravity through the inverse square law of gravitation, plus an additional term that varies with the comoving distance (UYF-Field). The model is an ΛFRW-Cosmology starting from the modification of the gravity by explicitly incorporating Mach's Principle through an additional term large-scale in the gravitation; the source of this field is the ordinary baryonic matter. It`s deduced from the Matter-radiation decoupling in the early universe. This additional term of gravity UYF result null in the inner solar system, weakly attractive in interstellar ranges, very attractive in ranges comparable to the clusters of galaxies, and repulsive in cosmic scales, in agreement with astronomical and laboratory observables. This term explains dark energy, removes the incompatibility between the density of matter and the flatness of the universe in ᴧFRW-Cosmology; allows the theoretical deduction of the Hubble-Lemaitre Law, between other relevant consequences. Additionally to discuss other relevant astrophysics consequences: Birkhoff Theorem, Virial Theorem, the missing mass of Zwicky, gravitational lenssings, the BAO and the gravitational redshift in AGN, provides an additional contribution for the gravitational redshift that increase the until an factor of ~4, which has resolved the Arp controversy. Also we show the crude explanations of Pioneer anomaly, we obtain as the additional contribution of the acceleration of gravity due to UYF-Field. It is concluded that the dark energy and the missing dark mass can be approached with the usual physics as the large-scale modification of the Gravitation.
Floristic Composition and Ecological Characteristics of Tehsil Samar Bagh District Lower Dir
Authors: Ullah Muhammad Rizwan
Published: January 2024

Usually identification of the flora all over the world is considered to be important and necessary because it plays a vital role to reserve National flora. The current study was conducted to explore and asses the floristic composition and ecological characteristics of Samar bagh District Dir lower along with their family, botanical name, habit, life form and leaf size classes. The flora of Tehsil Samar bagh comprises up of 120 species belonging 49 families. These 49 families consist of 6 gymnosperm species of family Pinaceae and Cuperassesceae, 8 monocot species of family Amaryllidaceae, Cyperaceae, Poaceae and 104 dicot species of 44 different families. As per the plant habit, there are 75 species of herb, 13 species of shrub and 32 species of tree. The leading and well-expressed family was Asteraceae attending 12 taxa, followed by Rosaceae with 10, Solanaceae with 9, papilionaceae with 7, Moraceae and Poaceae with 5, Fagaceae, Brassicaceae, Euphorbiaceae, Lamiaceae and Amaranthaceae contributing 4 plant species. The Life form and leaf size classes were managed by Raunkiaers system which displays that the headmost life form class was therophytes with 47 species, followed by nanophanerophytes with 21 species, chamaephytes with 13, and then by megaphanerophytes, hemicryptophytes, Geophyte and microphanerophytes. In leaf size classes leading class was microphyll representing 38 species followed by mesophyll with 37, nanophyll 24, macrophyll 9, leptophyll 7 and megaphyll with 5 species. Therophytes were observed dominant with high percentage, demonstrating that this area is a part of semi-arid zone of Khyber Pakhtunkhwah, Pakistan and indigenous people of this area thoroughly and extensively demolish and uproot the plants for burning purposes.
The Mesocolon, the Surgical Anatomy and Optimization of Resection, A Review of Literature
Authors: AS Abdulsamad
Published: January 2024

Colorectal cancer is one of the most common cancers worldwide, in this article we will discuss the history of anatomic approach of the colorectal cancer, the surgical importance of the mesentery of the colon, how to approach the surgical resection of the colon with maximizing the lymph nodes harvest targeting the lympho vascular sheet contained within the mesentery.
Impact of Consciousness Energy Healing Treatment on the Physicochemical and Thermal Properties of an Anticancer Drug 6-Mercaptopurine
Authors: G Nayak
Published: January 2024

Mercaptopurine is an antineoplastic chemotherapy drug is used for the treatment of cancer, Crohn's disease, ulcerative colitis, autoimmune diseases, etc. In this scientific study, the impact of the Trivedi Effect®-Consciousness Energy Healing Treatment on the physicochemical and thermal properties of 6-mercaptopurine was evaluated using the modern analytical technique. The test sample 6-Mercaptopurine powder was divided and named into control and treated sample. The control sample did not receive the Biofield Energy Treatment; whereas, the treated sample received the Biofield Energy Treatment remotely by a well-known Biofield Energy Healer, Gopal Nayak. The particle size values in the treated 6-mercaptopurine sample were significantly decreased by 10.18% (d10), 10.59% (d50), 7.62% (d90), and 9.17% {D(4,3)}; thus, the specific surface area was significantly increased by 10.28% compared to the control sample. The powder XRD peak intensities and crystallite sizes of the treated 6-mercaptopurine were significantly altered ranging from -43.40% to 23.33% and -37.09% to 136.67%, respectively; whereas the average crystallite size was significantly decreased by 11.04% compared with the control sample. The latent heat of evaporation and latent heat of fusion of the treated 6- mercaptopurine were significantly increased by 11.81% and 14.97% compared with the control sample. The total residue amount was significantly increased by 6.44% in the treated sample compared with the control sample. The maximum thermal degradation temperature of the 1st, 2nd, and 3rd peaks of the treated sample was altered by 1.55%, 0.18%, and -1.29% compared with the control sample. It was concluded that the Trivedi Effect®-Consciousness Energy Healing Treatment might have generated a new polymorphic form of 6-mercaptopurine which would offer better solubility, absorption, and bioavailability compared with the control sample. The Biofield Energy Treated 6-mercaptopurine would be more efficacious against acute lymphocytic leukemia, chronic myeloid leukemia, Crohn's disease, ulcerative colitis, and autoimmune diseases.
Diagnosis of Breast Cancer Using a Single Hair
Authors: J James Veronica
Published: January 2024

It is now twenty years since this test was first published in Nature and still women are suffering through mammograms. I ask why? In this time over four thousand tests have been run. No false negatives were found. False positives have been proved not false only much too early. Surely that is enough!
Dunaliella salina and Haloferax Volcanii Synergistically Attenuate Skin Cancer in Vitro
Authors: Cohen Guy
Published: January 2024

Skin cancer, including both melanoma and non-melanoma, is the most common type of malignancy, which causes substantial morbidities and mortalities. Although significant increase in the understanding of skin cancer formation and the development of novel personalized drug regimens has occurred, new treatment options are always of need. The use of natural compounds to alleviate the symptoms or even to prevent and treat cancer has long been proposed. Specifically, the use of marine-based organisms as a source for cancer cure and remedy is being evaluated extensively. The objective of the current study was to assess the ability of the green microalgae Dunaliella salina, the Dead-Sea-derived Haloferax volcanii, and its combinations to treat skin cancer in vitro. The results demonstrate the Dunaliella and Haloferax can reduce sarcoma and basal cell carcinoma cellular growth. Importantly, their combination act synergistically in a caspase3 independent manner. Moreover, a synergistic action was found when evaluated sarcoma cell invasion rate, which was completely blocked at pharmacological relevant amounts of the compounds. Collectively, the results demonstrate that the combination of Haloferax volcanii and Dunaliella salina can be used as a new treatment for skin cancer. The specific mechanism of action and further in vivo validation studies are of need.
Uncommon Association: Primary Malignant Melanoma of the Eyelid and Palpebral Conjunctiva
Authors: Alaoui A El harrouni
Published: January 2024

Ocular melanoma of the eyelid and conjunctival is extremely rare primary ocular malignant tumor in adults. The simultaneous occurrence of both lesions in one eye are uncommonly seen in practice. We report a case of ocular melanoma of the eyelid and conjunctival developed on one eye of a 71-year-old male patient that the reported had grown in size over the last four years
Survival of Women with Breast Cancer at Pointe Noire (Congo Brazzaville)
Authors: CFS Ngatali
Published: January 2024

Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. While the 5-year survival of patients with local breast cancer varies around 98.8%, this survival rate drops to around 26.3% for metastatic patients. The objective of this study was to determine the survival of patients with breast cancer in resourcelimited settings. Patients and Methods: It was a cross-sectional descriptive study performed in the cancer ward at Pointe Noire General Hospital from 1 January 2013 to 31 December 2018, for duration of 6 years. 70 records of patients over 18 years of age with histological evidence and an extension assessment involving a thoraco-abdominal CT or chest X-ray and / or abdominal ultrasound. The treatments received included: surgery, chemotherapy, radiotherapy and hormone therapy targeted therapy. The variables studied were: age, level of education, delay of consultation, histological type, histological grade, stage of extension, type of treatment and survival. Survival was calculated by Kaplan Meier method. The chi-square test was used to search for a correlation between the variables. Results: The average age was 51±12 years old. The extremes were 27 years and 79 years old. The most represented level of education was the primary level in 63 % of cases. The most represented stage was locoregional stage in 57 % of cases and metastatic stage in 33 % of cases. The most represented histological type was invasive ductal carcinoma in 97 % of cases. The most represented histological grade was Scharff grade III Richardson bloom in 68 % of cases. The treatment Anthracycline-based chemotherapy was more used in 74 % of cases. Surgery was used in 49 % of cases; radiation therapy was use in 26 %. Bivariate analysis revealed the lack of correlation between delay to consultation and stage of extension p˃0.05. There was no correlation between age and the stage of extension, p <0.05. The mean patient follow-up time was 22 ± 15.45 months. The overall survival was 39 months. The median survival of local, locoregional and metastatic stage was respectively 25 months, 29 months, 29 months, P> 0.05. Patients treated with anthracyclines were greater than that of patients treated with taxanes in combination was 48 months, p˂ 0.05, results significant. Conclusion: Breast cancer remains an incurable disease, its survival remains low despite diagnostic and therapeutic advances that remain difficult to access for our resource-poor developing countries. Patients are treated with conventional surgery, chemotherapy (anthracyclines and taxanes), radiation therapy, hormone therapy and targeted therapy are not used in optimal way in our context.
Radon Concentration Potential and Radiological Health Risks in Benue South Groundwater Sources
Authors: A Ichoja
Published: January 2024

The attendant health consequences arising from both the consumption of thawed radon and the inhalation of released radon air and its progenies emanating from the various drinking water sources in our community underscores the relevance of the current research. This pioneering study attempts to evaluate the Rn-222 concentration, the annual committed effective dose (ACED) and the related health risk factors of randomly selected 26 water samples from Apa and Agatu Local Government Areas (LGAs), Benue South, Nigeria. The results of the analysis via liquid scintillation counter, revealed the highest radon values of 13.3651.065 Bq/l and 18.2481.740 Bq/l for well water samples higher than the action level of 11.1 Bq/l by USEPA were found in the villages of Apa and Agatu LGAs respectively, while 5.5510.479 Bq/l lower than the tolerance limit was recorded for the surface water samples. The annual committed effective doses estimated for the different ICRP age groups (3 months, 1 year, 5 years, 10 years, 15 years and above 17 years) were below the acceptable 1 mSv/y baseline but displayed a significant and consistent rise with the age and water consumption frequency of the populace. Excess life cancer risks (ELCR) and the induced lung cancer cases per year per million persons (LCC) for ingestion and inhalation of radon by the inhabitants of the study areas were calculated. ELCRing and ELCRinh mean values of the radionuclide showed different variations below the standard reference line. The average values recorded for the lung cancer cases due to ingestion and inhalation of radon (LCCing) and (LCCinh) and the probability of an individual developing cancer over a lifetime exposure to radioactive element (ELCR) were found to be significantly lower than the suggested 170 – 230 per year per million persons and 0.29 mSv/y global mean value respectively. This implies that the evaluated radon parameters for ingestion and inhalation in the study areas do not pose any immediate radiological health effects to members of the public but periodic monitoring of the quality of the groundwater sources should be encouraged.
Festered and Fenced-Lymphoepithelial Carcinoma Lung
Authors: A Bajaj
Published: January 2024

Lymphoepithelial carcinoma is an exceptionally discerned, primary pulmonary carcinoma with a distinct syncytial pattern of tumour evolution. Lymphoepithelial carcinoma incriminates centric or peripheral pulmonary parenchyma with equivalent predilection. Median age of disease emergence is 51 years to 57 years. Lymphoepithelial carcinoma lung occurs due to Epstein Barr virus (EBV) infection and malignant metamorphosis triggered by dysregulation of NFkB pathway, loss of type I interferon (IFN) genes and concordant signatures by APOBEC family of genes. Tumefaction is composed of enlarged, polygonal cells pervaded with abundant or variable eosinophilic cytoplasm, vesicular nuclei and prominent, eosinophilic nucleoli. Tumour cells are circumscribed by quantifiably variable lymphoid and plasma cell infiltrate. Tumour cells appear immune reactive to squamous epithelial cell biomarkers as CK5/6, p40 or p63 whereas in situ hybridization (ISH) for discerning Epstein Barr encoded small RNAs (EBER) appears optimal. Lymphoepithelial carcinoma lung requires segregation from neoplasms such as poorly differentiated adenocarcinoma, NUT pulmonary carcinoma, malignant melanoma, lymphoma confined to pulmonary parenchyma, metastatic undifferentiated carcinoma of nasopharynx or metastatic medullary carcinoma arising from breast of colon. Stage I and stage II neoplasms are subjected to comprehensive surgical extermination whereas stage II, stage III or advanced grade neoplasms may be managed with surgical eradication in combination with adjuvant radiotherapy or chemotherapy.
Mental Health Issues and Frailty
Authors: KS Murty
Published: January 2024

As the population continues to age, it becomes pertinent to consider the experience and quality of life of older adults. With the advancement of age, older adults experience many physical challenges (e.g., mental health issues and aspects of frailty) and changes in their everyday lives. Frailty can be an outcome of decreased movement, stimulation, and confidence. Mental health issues like anxiety and depression can occur from changes in self-perception, abilities, and relationships. Socialization is affected by changes seen with aging, even though a social support system is an integral part of successful aging. For health care professionals working with older adults, it is important to provide education about mental and physical health changes to assist older adults maintaining their well-being and thrive as they age. Encouraging older adults to seek timely and necessary help to handle challenges and changes as needed is also a productive way to foster successful aging. This paper aims to discuss existing knowledge mental health and frailty with the hope that health care professionals may find it useful to stabilize and diversify the care older adults receive, thereby improving quality of life and reducing mental health and frailty issues.
Physical-Sports Activity Habits of Colombian Nationals and Migrants Residing in the City of Sincelejo
Authors: Medina Jesús León Lozada
Published: January 2024

The investigation of physical activity habits is a common process in different contexts, so the present study aimed to analyze the physical activity habits of Colombian nationals and migrants residing in the city of Sincelejo. Within the framework of the project called "Citizen Culture and Integral Formation", a descriptive cross-sectional study was developed and a sample of 3464 people was taken. It can be concluded that 8 out of 10 migrants who engage in physical activity are located in strata 1 and 2, and that women prefer aerobics, walking or running, and men prefer walking, running or playing soccer. It is recommended that suitable spaces be guaranteed for the practice of sports for social and cultural integration.
The Effects of Birth Weight Index on Motor, Cognitive Function and Relationship with Some Personality Characteristics of Children
Authors: Ezabadi Rosa Rahavi
Published: January 2024

Objective: The aim of this study was to determine the effect of birth weight index on motor, cognitive function and relationship with some personality characteristics of children. Methods: Population for this study included of 32 low birth weight and 35 normal birth students randomly selected. The mean age was 8, 04 ± 1. The Movement Assessment Battery for Children-2 test was used to assess motor function and Draw-APerson Color test was used to assess cognitive function and personality characteristics. Results: The result of Manova analyses and t test indicated that normal birth children had significantly better performance in fine Motor Function and cognitive function compared to children with low birth weight. In addition, the result of Spearman correlation analyses found no significant relationship between the personality traits of the two groups. Conclusions: The findings revealed that children with normal birth had higher performance in some motor and cognitive performance compared to children with low birth weight. Therefore, it is necessary for children to benefit from intensive care and exercise interventions in terms of motor and cognition from the very first years of life.