bluuebunny/crossref_metadata_2025 huggingface dataset:
An adaptive attack on Wiesner's quantum money
Authors: Nagaj Daniel , Sattath Or , Brodutch Aharon , Unruh Dominique
Published: February 2021

Unlike classical money, which is hard to forge for practical reasons (e.g. producing paper with a certain property), quantum money is attractive because its security might be based on the no-cloning theorem. The first quantum money scheme was introduced by Wiesner circa 1970. Although more sophisticated quantum money schemes were proposed, Wiesner’s scheme remained appealing because it is both conceptually clean as well as relatively easy to implement. We show efficient adaptive attacks on Wiesner’s quantum money scheme [1] (and its variant by Bennett et al. [2]), when valid money is accepted and passed on, while invalid money is destroyed. We propose two attacks, the first is inspired by the Elitzur-Vaidman bomb testing problem [3, 4], while the second is based on the idea of protective measurements [5]. It allows us to break Wiesner’s scheme with 4 possible states per qubit, and generalizations which use more than 4 states per qubit. The attack shows that Wiesner’s scheme can only be safe if the bank replaces valid notes after validation.
An improved asymptotic key rate bound for a mediated semi-quantum key distribution protocol
Authors: Krawec Walter O.
Published: February 2021

Semi-quantum key distribution (SQKD) protocols allow for the establishment of a secret key between two users Alice and Bob, when one of the two users (typically Bob) is limited or “classical” in nature. Recently it was shown that protocols exists when both parties are limited/classical in nature if they utilize the services of a quantum server. These protocols are called mediated SQKD protocols. This server, however, is untrusted and, in fact, adversarial. In this paper, we reconsider a mediated SQKD protocol and derive a new proof of unconditional security for it. In particular, we derive a new lower bound on its key rate in the asymptotic scenario. Furthermore, we show this new lower bound is an improvement over prior work, thus showing that the protocol in question can tolerate higher rates of error than previously thought.
Spectroscopic Signature and Structure of Active Sites in Ziegler-Natta Polymerization Catalysts revealed by Electron Paramagnetic Resonance
Authors: Ashuiev Anton , Humbert Matthieu , Gajan David , Norsic Sebastien , Blahut Jan , Searles Keith , Klose Daniel , Lesage Anne , Pintacuda Guido , Raynaud Jean , Monteil Vincent , Copéret Christophe , Jeschke Gunnar
Published: February 2021

Despite decades of extensive studies, the atomic-scale structure of the active sites in heterogeneous Ziegler-Natta (ZN) catalysts, one of the most important processes of the chemical industry, remains elusive and a matter of debate. In the present work, the structure of “active sites” of ZN catalysts in the absence of ethylene, referred to as “dormant active sites”, is elucidated from magnetic resonance experiments, carried out on samples reacted with increasing amounts of BCl3 so as to enhance the concentration of active sites and observe clear spectroscopic signatures. Using EPR and NMR spectroscopies, in particular 2D HYSCORE experiments complemented by DFT calculations, we show that the activated ZN catalysts contain bimetallic alkyl-Ti(III),Al species whose amount is directly linked to the polymerization activity of MgCl2-supported Ziegler-Natta catalysts. This connects those spectroscopic signatures to the active species formed in the presence of ethylene, and enables us propose an ethylene polymerization mechanism on the observed bimetallic alkyl-Ti(III),Al species based on DFT computations
TMtopo Dataset — Quantum Geometries and Density Topology for 1.1k Transition Metal Complexes
Authors: Teixeira Filipe , Silva-Santos Edgar , D. S. Cordeiro M. Natália
Published: February 2021

In this work, we report the TMtopo data set containing optimized geometries, quantum calculated properties, and quantum topological descriptors for 1110 first row TM complexes. Properties were computed at the TPSSh/Def2-TZVP level of theory and the quantum topological descriptors were collected under the framework of the Quantum Theory of Atoms in Molecules (QTAIM), including a systematic topological survey of the Laplacian of the electron density, ∇2ρ(r). This survey yielded novel insights on the proliferation of inner Valence Shell Charge Concentrations (iVSCCs, local minima of ∇2ρ(r)) in the metal center, suggesting that their number is determinant for the stabilization of the metal center in a more intense manner than their arrangement opposing each of the metal’s ligands (Inorg. Chem. 2016, 55, 3653). Pairwise representation of the collected properties revealed overall low correlation, although some structure could be perceived in the data (specially when considering the topological features of ∇ 2 ρ(r)). This suggests that the TMtopo data set could be usefully exploited in the data-driven discovery of new TM complexes with interesting properties for applications in as catalysis, opto-electronics and sustainable energy production and storage.
Validación predictiva de un método de clasificación funcional en adultos mayores
Authors: García-Arango Víctor , Osorio-Ciro Jorge , Aguirre-Acevedo Daniel , Vanegas-Vargas Catalina , Clavijo-Usuga Carmen , Gallo-Villegas Jaime
Published: February 2021

Objetivo. Evaluar la validez predictiva de un método de clasificación funcional (CF) sobre el uso de los servicios de urgencias y hospitalización, mortalidad y costos de la atención en salud en adultos mayores.

Métodos. Estudio de cohorte retrospectivo que incluyó 2 168 adultos mayores en un programa de atención de las enfermedades crónicas no transmisibles (ECNT) en Medellín (Colombia). Los pacientes fueron estratificados según un método de CF con base en el estado funcional, presencia de factores de riesgo y control de la comorbilidad. Durante un año de seguimiento, se evaluó la validez predictiva de la CF sobre los desenlaces estudiados; se midieron la discriminación y la calibración con el estadístico-C y de Hosmer-Lemeshow (H-L), respectivamente.

Resultados. El promedio de edad fue 74,6 ± 7,9 años; el 40,8% (n = 884) fueron hombres y 7,7% (n = 168) murieron. El riesgo de muerte (razón de posibilidades [OR, por su sigla en inglés]: 1,767; 3,411; 8,525), hospitalización (OR: 1,397; 2,172; 3,540) y un costo elevado de la atención en salud (OR: 1,703; 2,369; 5,073) aumentaron en la medida que hubo un deterioro en la CF, clases 2B, 3 y 4, respectivamente. El modelo predictivo para el desenlace muerte mostró una buena capacidad de discriminación (estadístico-C = 0,721) y calibración (estadístico de H-L = 10,200; P = 0,251).

Conclusión. Existe una relación de dosis y respuesta entre el deterioro de la CF y un riesgo más elevado de muerte, hospitalización y costo elevado. La CF tiene validez predictiva para la tasa de mortalidad y podría utilizarse para la estratificación de adultos mayores en programas de atención de las ECNT con miras a dirigir las acciones de intervención.
Cesarean sections in Brazil’s teaching hospitals: an analysis using Robson Classification
Authors: Mendes Yluska Myrna Meneses Brandão e , Rattner Daphne
Published: February 2021

Objective. To determine the distribution of cesarean sections performed in teaching hospitals participating in the Project for Improvement and Innovation in the Care and Teaching of Obstetrics and Neonatology (Apice ON) using the Robson Classification.

Methods. Cross-sectional descriptive study on cesarean sections performed at Apice ON hospitals according to the Robson Classification, using secondary data from the 2017 Live Births Information System on the year prior to project implementation, hence a baseline study. Hospitals are described according to their geographic distribution and cesarean section rates, using absolute and relative frequencies.

Results. The proportions of newborns by Robson groups were similar to those proposed by the World Health Organization, except for Group 5 (with previous cesarean section) and Group 10 (preterm), with regional differences. The teaching hospitals’ average cesarean section rates ranged from 24.8% to 75.1%, exceeding by far the recommended values, even in Robson groups considered low risk for cesarean section (Groups 1 to 4).

Conclusions. Brazilian teaching hospitals displayed cesarean section rates higher than those recommended by the World Health Organization for all groups; a worrisome fact, as by teaching they induce attitudes in future professional practices. These results highlight the importance of a reliable information system. Monitoring and evaluation of cesarean sections using the Robson Classification can be an important tool to guide management and propose actions to reduce rates. Countries with high cesarean section rates might explore this hypothesis in their teaching hospitals in order to define policies for the reduction of their rates.
Chamado à ação de São Paulo para prevenção e controle da hipertensão arterial, 2020
Authors: Campbell Norm RC , Schutte Aletta E , Varghese Cherian V , Ordunez Pedro , Zhang Xin-Hua , Khan Taskeen , Sharman James E , Whelton Paul K , Parati Gianfranco , Weber Michael A , Orías Marcelo , Jaffe Marc G , Moran Andrew E , Plavnik Frida Liane , Ram Venkata S , Brainin Michael , Owolabi Mayowa O , Ramirez Agustin J , Barbosa Eduardo , Bortolotto Luiz Aparecido , Lackland Daniel T
Published: February 2021

Cerca de ¼ dos adultos têm hipertensão arterial, que é o fator de risco isolado mais importante para morte (incluídas as mortes por cardiopatia e acidente vascular cerebral).

Existem políticas eficazes que poderiam facilitar escolhas pessoais saudáveis para evitar a elevação da pressão arterial e, se plenamente implementadas, podem prevenir a ocorrência da hipertensão arterial.

É fácil rastrear e tratar a hipertensão, MAS somente cerca de 50% dos adultos hipertensos estão cientes de sua condição, e apenas cerca de 1 em cada 7 é tratado adequadamente.

A prevenção e controle da hipertensão é o principal mecanismo de prevenção e controle das doenças não transmissíveis e um modelo para outros riscos de doenças não transmissíveis.

Tratamentos eficazes com mudanças de estilo de vida e medicamentos poderiam prevenir e controlar a hipertensão arterial na maioria das pessoas se aplicados sistematicamente à população; as intervenções simples são viáveis em todos os ambientes e podem melhorar a atenção primária.

É necessária a ação continuada e urgente a fim de obter mudanças efetivas nas políticas públicas e no sistema de saúde para prevenir e controlar a hipertensão arterial.
Vinculación de datos administrativos y su utilidad en salud pública: el caso de Ecuador
Authors: Orozco Fadya , Guaygua Santiago , López Villacis Danilo Hernán , Muñoz Fabián , Urquía Marcelo L
Published: February 2021

RESUMEN Los objetivos de este artículo son describir las características del abordaje de vinculación de bases de datos administrativos y sus usos en investigación en salud pública, y discutir las potencialidades y retos para su implementación en Ecuador. La vinculación de bases de datos permite integrar datos de una misma persona dispersos en distintos subsectores como salud, educación, justicia, inmigración y programas sociales, y posibilita investigaciones que informen una gestión más eficiente de programas y políticas sociales y de salud. Las principales ventajas del uso de bases de datos relacionadas son la diversidad de datos, la cobertura poblacional, la estabilidad temporal y el costo menor en comparación con la recolección de datos primarios. A pesar de la disponibilidad de herramientas para procesar, vincular y analizar grandes conjuntos de datos, el uso de este abordaje es mínimo en los países de América Latina. Ecuador tiene un alto potencial para explotar este abordaje, debido a la obligatoriedad del uso de un identificador único en la prestación de servicios de salud, que permite la vinculación con otros sistemas de información nacionales. Sin embargo, enfrenta una serie de retos técnicos, ético-legales, culturales y políticos. Para aprovechar su potencial, Ecuador necesita desarrollar una estrategia de gobernanza de datos que incluya normativas de acceso y uso de los datos, de manera simultánea con mecanismos de control y calidad de los datos, una mayor inversión en formación profesional en el uso de los datos dentro y fuera del sector salud, y colaboraciones entre entidades gubernamentales, universidades y organizaciones de la sociedad civil.
EMPIRICAL PERFORMANCE EVALUATION OF KNUTH MORRIS PRATT AND BOYER MOORE STRING MATCHING ALGORITHMS
Authors: S.DAWOOD SARHAN
Published: February 2021

Manyalgorithms have been proposed for string matching in order to find a specific pattern in a given text. These algorithms have been used in many applications such as software editors, genetics, Internet search engines, natural language processing, etc. Theaim of this paper is to evaluate the performance of two popularalgorithms:BoyerMoore (BM) and KnuthMorrisPratt (KMP) in terms of execution time. The algorithms have been programmed usingJava and Java Microbenchmark Harnessto evaluatetheirexecution timeusinganumber of experimentaltest scenarios.Resultsshowthat the BMalgorithm outperformed the KMPalgorithm in all test scenarios
Aspek Klinis dan Diagnosis Kandidiasis Vulvovaginal
Authors: Harminarti Nora
Published: February 2021

Candidiasis vulvovaginal is an infection of the vaginal and vulva area caused by yeast Candida. The most causative species is Candida albicans. This fungus is commensal in the vagina but it can become a pathogen, causing the infection under certain conditions. Several conditions can be risk factors for this infection. Women are mostly getting infections, especially of productive age. Complaints experienced cause disturbances in the form of itching accompanied by abnormal vaginal discharge. The clinician can make diagnostics based on anamnesis, clinical and microscopic examination. This paper provides information about the causes, risk factors, clinical symptoms, and laboratory testing.
Penggunaan Sistem Informasi Akuntansi untuk Usaha Mikro Kecil dan Menengah (UMKM) di Desa Kota Daro, Kabupaten Ogan Ilir
Authors: Hakiki Arista , Rahmawati Meita , Novriansa Agil
Published: February 2021

Sampai saat ini cukup banyak Usaha Mikro, Kecil dan Menengah (UMKM) yang mengalami kesulitan untuk memperoleh akses permodalan dari bank. Setelah ditelusuri mengapa UMKM kesulitan mendapatkan pinjaman dari bank, jawabannya mereka belum pernah melakukan pencatatan transaksi keuangan secara tepat, mereka tidak memahami tentang pembukuan dan laporan keuangan. Sistem informasi akuntansi merupakan kumpulan sumber daya, seperti manusia dan peralatan, yang dirancang untuk mengubah data keuangan dan data lainnya ke dalam informasi. Kehadiran Sistem Informasi Akuntansi bagi UMKM akan menjadi salah satu sarana untuk menyusun berbagai laporan yang sangat diperlukan oleh UMKM. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan pengetahuan bagaimana penggunaan Sistem Informasi Akuntansi (SIA) untuk UMKM di Desa Kota Daro Kabupaten Ogan Ilir. Pelaksanaan kegiatan dilakukan dengan menggunakan metode ceramah, tutorial, dan diskusi. Khalayak sasaran yang dipilih adalah para pelaku UMKM di Desa Kota Daro Kabupaten Ogan Ilir yang memiliki usaha yang beragam (sandang, pangan dan kerajinan umum) sebanyak 20 orang. Hasil pengabdian masyarakat ini menunjukkan bahwa sebagian besar pelaku UMKM di Desa Kota Daro tidak pernah melakukan pencatatan untuk setiap transaksi kegiatan usaha yang terjadi. Kegiatan pengabdian masyarakat berupa pelatihan SIA untuk UMKM ini membantu dalam membuka wawasan dan menambah ilmu pengetahuan para pelaku UMKM di Desa Kota Daro untuk mulai menggunakan SIA dalam kegiatan usahanya, minimal SIA manual yang paling sederhana.
Pengelolaan Dana ZISWaf Masjid Pintar di Desa Kota Daro II, Kecamatan Rantau Panjang, Kabupaten Ogan Ilir
Authors: Yuliana Sa'adah , Rostartina Eka , Teguh Muhammad , Saleh Muhammad Syirod , Apriani Deassy
Published: February 2021

Kegiatan pengabdian tentang pengelolaan dana ZISWaf masjid pintar bagi perangkat atau aparatur masjid bertujuan untuk memberikan pengetahuan tentang pengelolaan dana ZISWaf sehingga dapat mensejahterakan masyarakat desa, mengatur perekonomian masyarakat sekitar yang berlandaskan pada ajaran prinsip Islam serta dapat memperoleh pemahaman mengenai ZISWaf yakni Zakat, Infaq, Sadaqoh dan Wakaf baik dari praktek perhitungan  ZISWaf maupun dari segi pemahaman dan pembagian tentang ZISWaf.  Metode yang diterapkan dalam kegiatan ini adalah metode coaching dan bimbingan secara holistik step by step. Dari hasil yang dicapai terlihat bahwa pemahaman para peserta tentang ZISWaf masih belum sesuai yang diharapkan dikarenakan para peserta rata-rata masih terpaku dengan sistem manual dan ketidaktahuan mereka tentang pembagian ZISWaf baik jenis nya maupun perhitungannya. Diharapkan agar kedepanya pendampingan ini dirasakan manfaatnya untuk meningkatkan pemahaman mereka tentang ZISWaf.
Peran Financial Technology sebagai Alternatif Permodalan bagi UMKM di Desa Kerinjing, Kabupaten Ogan Ilir
Authors: Andaiyani Sri , Yunisvita Yunisvita , Tarmizi Nurlina
Published: February 2021

Era revolusi industri 4.0 merupakan tantangan bagi suatu negara untuk mengubah model bisnis konvensional kedalam sistem berteknologi. Penggunaan teknologi inovatif di bidang keuangan (Financial Technology) menuntut model bisnis konvensional untuk segera berubah kearah moderat. FinTech muncul seiring perubahan gaya hidup masyarakat yang didominasi oleh pengguna teknologi informasi untuk menjadi penghubung antara sektor finansial dengan pengguna atau masyarakat umum. Indonesia merupakan pasar besar bagi FinTech seiring dengan meningkatnya mayoritas pengguna teknologi internet untuk transaksi bisnis.FinTech sangat berpotensi menjadi salah satu solusi untuk mengatasi masalah kekurangan permodalan bagi UMKM. Fintech diharapakan menjadi altenatif solusi bagi UMKM bertempat tinggal jauh dari pusat kota untuk memperoleh permodalan. Berdasarkan pada fenomena diatas, tim pengabdian kepada masyarakat Fakultas Ekonomi Universitas Sriwijaya, telah melakukan edukasi mengenai peran FinTech sebagai alternative permodalan bagi UMKM di Desa Kerinjing, Kabupaten Indralaya. Kegiatan pengabdian kepada masyarakat dilaksanakan pada hari Rabu tanggal 12 November 2019.Peserta terdiri dari 0 orang pelaku UMKM di Desa Kerinjing dan sekitarnya. Tim pelaksana memberikan materi terkait dengan apa yang dimaksud dengan financial technology, manfaat  dari fintech dan dampak dari fintech. Peserta dapat membedakan fintech legal dan illegal.Fintech legal yang dimaksud adalah fintech yang terdaftar di Otoritas Jasa Keuangan (OJK). Sebagai evaluasi kegiatan, tim memberikan form kuisioner yang diisi oleh peserta. Berdasarkan hasil kuesioner, pemahaman peserta setelah diberikan edukasi Fintech telah mencapai 70 %.
Macroeconomic Determinants of Consumption Inequality in Nigeria: Does Agricultural Productivity Matter?
Authors: Aigheyisi Oziengbe Scott , Osemwengie Presley Kehinde
Published: February 2021

The paper examines the effect of agricultural productivity and other macroeconomic variables on consumption inequality in Nigeria. The ARDL approach to cointegration and error correction modeling was employed for the analysis. The study found that agricultural productivity and domestic investment reduce consumption inequality in the long run. FDI was also found to be associated with reduction in consumption inequality in the short run, but its long run effect was not statistically significant. Based on the evidence, the study recommends as measure to reduce consumption inequality in the country, increased investment in the agriculture sector to enhance its productivity, and improvement in the investment environment through infrastructural development, including energy, road, telecommunication infrastructure, favourable, tax policies, enhanced national security, etc. to encourage domestic investment and enhance the attractiveness of the economy to FDI.
Analysis of the landscape structure of Khibiny
Authors:   Moscow State University of Geodesy and Cartography, Moscow, Russia, S.F. Kolesnikov , E.S. Gorbatov ,   Schmidt Institute of Physics of the Earth RAS, Moscow, Russia
Published: February 2021

С помощью изучения космических снимков и маршрутных исследований проведено дешифрирование ландшафтов юго-западной части Хибин и на его основе создана ландшафтная карта. Анализ пространственной структуры ландшафтов показал, что в распределении растительности наблюдается хорошо выраженная высотная поясность. Вместе с тем на отдельных элементах рельефа наблюдаются нарушающие эту схему проявления азональности. На водно-ледниковых террасах происходит смена характера поверхности от лишенных растительности на бровке до лишайниковой тундры и зарослей карликовой и кривоствольной березы в тыловом шве. На дне мелководных и недавно осушенных озерных котловин в ледниковых цирках и на других незадернованных участках хорошо выражены мерзлотные формы рельефа аналоги которых встречены в поясе высокогорных каменистых пустынь. Вне зависимости от высотного положения эти формы рельефа развиваются сходным образом: по мере зарастания участков происходит их деградация.
Analysis of influential factors affecting workers’ productivity on highway construction projects during Covid-19 pandemic in Cagayan Valley Region, Philippines
Authors: Emer Tucay Quezon  , Arthur G. Ibanez
Published: February 2021

In highway construction projects, labor-oriented work is an integral part of the management process, requiring analysis of factors affecting labor productivity during Covid-19 pandemic. This research identified 53 influential factors affecting construction labor productivity at selected cities and towns in Cagayan Valley Region, Philippines. Due to the pandemic, the construction industries incurred substantial profit losses. More so, the construction workers are too much affected because of the Enhance Community Quarantine (ECQ) imposed by the local government. Results indicated there was laxity on the Covid-19 protocols. No health worker in the project site ranked the highest in the health & safety factor group with an RII of 0.97 and ranked 1st among 53 factors on the different groups. Besides, no safety engineer was assigned to the projects and ranked 2nd with an RII of 0.93. Among the 7 groups of factors, the health and safety group ranked 1st with 0.81, followed by the schedule compression group with an RII of 0.78. Hence, these two groups of factors have a strong relationship, as evidenced by number of workers reduced. It was learned that the contractors’ strategy was to increase the number of working days to cope with their schedules. Hypothesis testing supported that there are various significant factors influencing labor productivity loss during the Covid-19 pandemic, as suggested by more than 50% of the respondents.
Comparative investigation of sesquiterpene components of essential oils originating from intact plants and hairy root chamomile cultures
Authors: Éva Szőke  , Éva Lemberkovics
Published: February 2021

The importance of chamomile (Chamomilla recutita) inflorescence is widely known in classical and folk medicine, with the largest group of its effective constituents forming the essential oil (chamazulene, a-bisabolol, α-farnesene, trans-β-farnesene, spathulenol, cis/trans-en-in-dicycloethers). Among cultivated species, the Hungarian BK-2 contains more chamazulene in its essential oil than the German Degumil type, which is mainly cultivated for its a-bisabolol. Both components have important antiinflammatory activities. Wild populations can be easily distinguished from cultivated ones by their high amount of bisaboloides, particularly the flower of Hungarian Szabadkígyós wild type, which contained on average 48 % of the biologically active (-)-a-bisabolol. The population of Szabadkígyós has good salt tolerance which is important owing to global warming, because the proportion of saline areas is increasing worldwide. To keep the genome of Szabadkígyós having high (-)-a-bisabolol content, Szőke and research team used biotechnological methods. Sterile plantlets, were infected by Agrobacterium rhizogenes strains #A-4, #15834, #R-1601. The hairy root clones possessing the best growing and biosynthetical potential were multiplied for phytochemical investigations. Pharmacologically important compounds of their essential oils were followed in great detail. The amount of in vitro cultured terpenoids and polyin compounds was compared with that of in vivo plants. GC-MS studies showed that sterile chamomile cultures generated the most important terpenoid and polyin compounds characteristics of the mother plant. Berkheyaradulene, geranyl-isovalerat and cedrol as new components were identified in these sterile cultures. The main component of hairy root cultures (D/400, D/1, D/100 and Sz/400) was tr-b-farnesene and in addition one new compound: a-selinene was identified. Hairy root culture originated from chamomile collected in Szabadkígyós was intensive increased the essential oil content and pharmacological active compounds: (-) -α-bisabolol and β-eudesmol was also synthetized in large quantity. Furthermore, in vitro organized cultures were made from this population to obtain propagation material containing numerous active substances.
Should bone be considered fascia: Proposal for a change in taxonomy of bone- a clinical anatomist’s view
Authors: John J Sharkey
Published: February 2021

Fascia is the accepted term to describe integrated three-dimensional connective tissues that have failed to be described in a manner agreed by recognised anatomical authorities. It is proposed that the ambiguity concerning the seeming indefinability and lack of agreement is predominantly conceptual and partially technical. A call for the deconstruction of the word and a proposal for a change in taxonomy to include bone is proposed. Should bone can be viewed as a specialty of fascia it would make redundant descriptive terms “attaches”, “origin” and “insertion”. An agreed change in the definition to include bone would provide a fecund area of research. This paper proposes fascia as the original building material (mesenchyme) of embryology and therefore the true structural matrix that facilitates cellular specialty, including bone. It is proposed that it would be beneficial, to the widest disparate groups of researchers in human sciences, to include bone as fascia based on the supposition of specialty along a spectrum. Attention to structural aspects of fascia has resulted in insufficient attention being paid to the important unified tensegrity based three-dimensional functionality and morphological states. A spectrum is used to classify something in terms of its position on a scale between two extreme points. Concerning fascia, the two points of opposition are hardness to softness along a continuum of specialisation emerging as arachnoid, blood, mucus, bone and other. It seems instructive to suggest that the issue concerning the seeming indefinability and lack of agreement is predominantly conceptual and partially technical.
The bioactive ingredients and therapeutic effects of Marrubium vulgare - A review
Authors: Ali Esmail Al-Snafi  , Hussein Ali Al-Saedy  , Tayseer Ali Talab  , Wajdi Jabbar Majid  , Gaber El-Saber Batiha  , Jafari-Sales Abolfazl
Published: February 2021

Marrubium vulgare (Family: Lamiaceae) was used traditionally in the treatment of dyspeptic complains, pulmonary infections, cough, rheumatoid arthritis, night blindness, loss of appetite, as cholagogue, purgative, diuretic, bitter tonic, carminative and appetizer. The phytochemical analysis revealed that the plant contained alkaloids, sterols, steroids, terpenoids (diterpene), saponins, flavonoid, catecholic tannins, anthocyans, phenolic compounds and many other bioactive ingredients. The pharmacological investigations showed that the plant exerted anti-inflammatory, antiedematogenic, analgesic, antioxidant, antimicrobial, antidiabetic, cardiovascular hypolipidemic, antispasmodic and many other biological effects. This review discussed the bioactive contents and pharmacological activities of Marrubium vulgare.
Artificial intelligence in advanced pharmacy
Authors: Tamanna Sharma  , Abhinav Mankoo  , Vivek Sood
Published: February 2021

Artificial intelligence (AI) is Pharma's next frontier in life sciences. This article analyze about the recently techniques of AI that aims to imitate human intelligence functions i.e. with the help of Artificial intelligence & Robots ‘Automation become the result of Industrialization’, driven by the need to increase productivity, to achieve consistent quality products & to remove hazardous and heavy work from workers. Recent trends of AI in pharmacy are PAT, CFD, Pharmaceutical automation in research & development which give detailed information about techniques that has already been used in healthcare such as inhaler designs, drug absorption & dissolution and is disease focused. A robot for pharmaceutical applications has a bright future but with the rapidly aging population that urgently requires sophisticated medical devices & newer drugs, robotics systems are increasingly adopted for improved productivity and efficiency to meet this growing demand. However, robots manufacturers face several challenges in their effort to establish themselves in pharmaceutical applications. AI with robotics in the life of mankind has several advantages & disadvantages. Despite the increasingly rich AI literature from the drug discovery to care options AI techniques are used such as in ANN [artificial neural network], machine learning, AI in healthcare, AI in clinical practice. This research mainly concentrates around a few disease types: Cancer, Nervous system and cardiovascular diseases as they are life threatening. The future is always hard to predict, but it will be determined by AI as it would become the next frontier in pharmacy.
Bacterial cellulose membrane enriched with fibroblast growth factor associated with photobiomodulation: In vitro evaluation
Authors: Hananiah Tardivo Quintana  , João Paulo dos Santos Prado  , Alan de França  , Paulo Roberto Gabbai-Armelin  , Daniel Vitor de Souza  , Daniel Araki Ribeiro  , Nivaldo Antonio Parizotto  , Hernane da Silva Barud  , Ana Claudia Muniz Renno
Published: February 2021

One promising skin substitutes in the wound healing are the bacterial cellulose membranes (BCM). These biomaterials present nanostructures composed of microfibrils capable of forming three-dimensional pores that allow cell. In association with these biopolymers, several treatments are used, such as enrichment by growth factors and/or the application of photobiomodulation (PBM). Therefore, the aim of this study was to investigate the viability, proliferation and cytotoxicity of a BCM (culturing of Komagataeibacter xylinus), with or without FGF-2 in association with PBM therapy. In the characterization of BCM we saw that the membrane does not show great variations in pH and with the scanning electron microscopy it was possible to observe that the BCM has a denser and a porous side that allows the adhesion of fibroblasts, confirmed by histological staining and DAPI/Phalloidin. In vitro evaluation showed that the immunofluorescence (CaAM/EthD-1) for live and dead cells presented, in the groups with combined treatment at long-term of PBM and FGF-2, a greater quantity of live cells than with these isolated treatments and/or at short-term. However, in the short-term of combined treatment PBM and FGF-2 supplementation, fibroblasts and macrophages were more viable by Alamar Blue, in direct and indirect contact respectively. The comet assay did not show cytotoxicity for DNA damage in fibroblasts indirect contact with membrane extract. The results highlight the potential of association of FGF-2 supplementation with the application of PBM for use with BCM, due to its promoted increased cell density at long-term and improved viability in fibroblasts and macrophages at short-term.
Evaluation of α-amylase expression and analysis of phytochemical in the leaf callus tissue of Rauvolfia serpentina (Linn.) Benth. Ex Kurz exposed to Cyclodextrin
Authors: Ram Kishore P  , Vikram V  , Lakshmi Sundaram R  , Selvapalam  N  , Shaikmuhammad Sohail  , N Hariram
Published: February 2021

Rauvolfia serpentina (Linn.) Benth. Ex Kurz belongs to the family Apocynaceae. The objective of the present study was to establish an effective protocol for the regeneration of leaf explants from R. serpentina and to study the α-amylase expression and phytochemical profiling by gas chromatography and mass spectrometry (GC-MS). Further antibacterial activity was studied using silver, gold, and copper nanoparticles. The leaf explants were cultured on Murashige and Skoog (MS) medium containing Benzyl amino purine (BAP) (2.0 mg/L-1) and Naphthalene acetic acid (NAA) (1.0 mg/L-1) induced the formation of callus and expressed α-amylase with underexposed to Cyclodextrin. Explants growing on MS medium fortified with 2,4-Dichlorophenoxy acetic acid (2,4-D) (1.0 mg/L-1), NAA (1.0 mg/L-1) with and without BAP (2.0 mg/L-1) and showed a maximum concentration of protein on the 75th day. Synthesis of a-amylase enzyme was expressed 40 days old culture and were confirmatic by western, further Silver, gold, and copper nanoparticles were synthesized using the ethyl acetate extract of callus tissue and subjected to thin-layer chromatography (TLC), which resolved 5 bands. These five bands were characterized by Fourier Transform Infrared (FTIR) Spectroscopy and screened for antimicrobial and antioxidant activities. TLC band 4 alone showed inhibitory activity against both Gram-negative and positive bacteria and potent antioxidant activity. For the first time, α-amylase was found in the callus extract by SDS-PAGE and confirmed by Western blot. The fourth band of TLC from the ethyl acetate extract as well as silver and gold nanoparticles synthesized using this extract revealed pronounced antimicrobial and antioxidant activities. GC-MS analysis revealed 26 compounds, which included mainly the phytosterols and fatty acid esters.
Pesquisa de Campo em Território Tradicional na Fronteira Brasil/Paraguai
Authors: Rodrigues Andréa Lúcia Cavararo , Urquiza Antonio Hilario Aguilera
Published: February 2021

Este texto traz um relato de experiência e refl exão acerca da importância do trabalho de campo na região fronteiriça envolvendo territórios tradicionais. O objetivo é descrever as vivências e experiências adquiridas no trabalho de campo no território tradicional kaiowá, na fronteira Brasil/Paraguai. Mesmo diante das difi culdades encontradas no Oguata, utilizando a terminologia guarani sobre o signifi cado de caminhada, essa experiência foi muito rica, proporcionando momentos de refl exão, questionamentos e até mesmo indignação diante do panorama que se verifi ca a partir da convivência com a população Kaiowá - Paĩ Tavyterã, pois as difi culdades que já enfrentaram, e ainda enfrentam, para viver no território tradicional ainda persistem e estão longe de terminar. A base metodológica é própria dos estudos antropológicos, com interface no direito dos povos tradicionais e, além da pesquisa bibliográfi ca, manteve-se a preferência pelo trabalho de campo. O estudo permite concluir que o trabalho de campo e o envolvimento do pesquisador acadêmico com apoio do professor orientador favorecem a formação e consolidação do nível de excelência nos resultados alcançados.
Identifikasi Kebutuhan Pembelajaran Praktik Servis Sepeda Motor dengan Konsep Teaching Factory
Authors: Handoyono Nurcholish Arifin , Purnomo Sigit
Published: February 2021

The research aims to identify the learning needs of motorcycle service practice practices with the concept of teaching factory in the PVTM Study Program Universitas Sarjanawiyata Tamansiswa. This type of research is descriptive quantitative. The subject of the study was the head of the PVTM laboratory. The object of the study was the need to learn motorcycle service practice. Data collection by observation, interview, and documentation. Data were analyzed by means of quantitative descriptive. The results showed that: (1) Analysis of the learning needs of motorcycle service practice practices with the concept of teaching factory consists of three processes, namely preparation, learning, and evaluation; and (2) Overview of equipment owned by the PVTM Motorcycle Workshop Production Unit as many as 16 equipment (48.48%) are used classically, while 17 equipment (51.52%) are used in groups. From the equipment, there are 7 equipment (21.21%) categorized as very good, 7 equipment (21.21%) categorized as good, 4 equipment (2.12%) categorized as enough, 13 equipment (39.40%) categorized as less, and 2 equipment (6.06%) categorized as very less. Overall, a percentage of 80.30% is categorized as good.
Association of Air Pollution Levels to Atmospheric Weather Regimes over Europe
Authors: Muntasir A. Ibrahim , Gabriele Curci , Farouk I. Habbani , Fred Kucharski , Paolo Tuccella , Susanna Strada
Published: February 2021

The ability to link air pollution to weather regimes may help municipalities to activate in advance plans to protect citizens from severe episodes of air pollution. The aim of this work was to associate the atmospheric circulation patterns and air pollution over Berlin using observational data from three air quality monitoring stations (Urban, Suburban and Traffic stations) during the period January 1990 to December 2002, with weather type’s classifications issued in the frame of the European Cooperation in Science and Technology project (COST733). Results obtained in this work shows similar higher ozone (O3) concentrations and weather regime type during the summer season for both the three stations and the two cluster methods used viz. Self-Organizing Maps (SOM) and cluster analysis of principal components (CAP). The highest concentration level of ozone was observed in the suburban station. High pollution that occurred from the particulate matter (PM10) was observed in the urban station during the winter season. The highest nitrogen dioxide (NO2) value was observed in the traffic station during the spring season. However, the traffic station is probably not a very good indicator of the sensitivity of air quality in meteorology, because it is too much affected by local sources.
Evaluation of In-cage Filter Paper as a Replacement for Sentinel Mice in the Detection of Murine Pathogens
Authors: O'Connell Kathryn A , Tigyi Gabor J , Livingston Robert S , Johnson Daniel L , Hamilton David J
Published: February 2021

Recent studies have evaluated alternatives to the use of live animals in colony health monitoring. Currently, an alternative method that is suitable for all rack types and that has been verified to detect the infectious agents most commonly excluded from mouse colonies is unavailable.
We compared the use of filter paper placed on the inside floor of mouse cages to the traditional use of sentinel mice in the detection of several prevalent murine pathogens including mouse hepatitis virus (MHV), murine norovirus (MNV), minute virus of mice (MVM), mouse parvovirus (MPV), Theiler
murine encephalomyelitis virus (TMEV), Helicobacter spp., Syphacia obvelata, and Aspiculuris tetraptera. Experimental groups comprised 7 cages containing either 2 pieces of filter paper on the cage floor or 2 ICR sentinel mice. Soiled bedding from pet-store mice was transferred
to the experimental cages weekly for 8 wk. At 1 and 2 mo after bedding transfer, the filter papers were evaluated by PCR and sentinel mice were tested by serology and fecal PCR. Filter papers detected all pathogens as effectively (MHV, MNV, MPV, MVM, TMEV S. obvelata, and A. tetraptera)
or more effectively (Helicobacter spp.) than sentinel mice at both time points. Filter papers more readily detected pathogens with a high copy number per RT-PCR analysis than a low copy number. Helicobacter spp. were not detected by sentinel mice at either time point. These results
indicate that the use of filter paper placed on the interior floor of empty mouse cages and exposed to soiled bedding is efficient in detecting bacteria, endoparasites, and most of the common mouse viruses included in an animal health monitoring program.
Dircurso pronunciado por el embajador de la Argentina Dr. Eduardo Colombes Marmol
Authors: Colombes Marmol Eduardo
Published: February 2021

Bajo los auspicios del Exemo. Gobierno Peruano e intermedio del Ministerio de Educación Nacional y por iniciativa del Instituto Cultural Peruano Argentino, esta ilustre Universidad Mayor de San Marcos, de tan altos blasones intelectuales, cuna y foco de nuestra cultura indo-española, cuatro veces centenaria, rinde un solemne homenaje en memoria del ilustre americano y ciudadano de mi patria: DOMINGO FAUSTINO SARMIENTO.
Perfil dos endodontistas de uma metrópole brasileira quanto ao atendimento odontológico a pacientes com necessidades especiais
Authors: Gutierrez Gabriela Mancia , Gonçalves Ana Lurdes Conte Acunha , Bonacina Carlos Felipe , Diniz Michele Baffi , Santos Maria Teresa Botti Rodrigues , Yamamoto Ângela Toshie Araki , Lira Adriana De Oliveira
Published: February 2021

O objetivo do estudo foi caracterizar o perfil dos endodontistas do estado de São Paulo, Brasil em relação ao tratamento odontológico de pacientes com necessidades especiais (PNE). Um questionário online sobre capacitação do profissional e dados sobre o atendimento odontológico de PNE foi enviado para 3.500 endodontistas registrados no Conselho Regional de Odontologia de São Paulo. Dentre os 138 profissionais que retornaram, 57,2% eram do sexo feminino; 34,8% estavam na faixa etária entre 31 e 40 anos; 42,8% tinham entre 11 e 20 anos de formados; e 38,4% possuíam 11 a 20 anos de especialidade. Apenas 22,5% eram capacitados para o atendimento de PNE, sendo que desses, 58,1% tiveram apenas aula teórica. Dos que não receberam capacitação na pós-graduação, 80,4% gostariam de ter recebido. Com relação ao interesse em cursos de atendimento a PNE após a especialização, observou-se que apenas 15,9% realizaram algum tipo de curso, a maioria apenas teórico. Em relação às dificuldades durante o atendimento de PNE a "falta de colaboração do paciente durante o atendimento" foi citada por 74,6%, a "insegurança devido à falta de preparo profissional" por 55,0%. A análise da associação das variáveis pelo teste Qui-quadrado apontou que quanto maior o tempo de formação, menor essa dificuldade (p=0,0415). Os especialistas encontram mais dificuldades comparados aos que tem formação associada (mestrado e doutorado) (p=0,0369). Não houve associação significativa entre as dificuldades e o tipo de instituição de formação (pública ou privada) (p0,05). O panorama atual da formação do endodontista não contempla o atendimento as pessoas com necessidades especiais.
PENGGUNAAN SIMBOL PADA PROSES INTERAKSI SIMBOLIK SISWA TUNAGRAHITA DAN GURU DI SEKOLAH LUAR BIASA
Authors: Rahman Khafi Maulana , Purnomo Agustina M. , Agustini Agustini
Published: February 2021

Symbolic interaction between students and teachers as a process of action and reaction involving an exchange of symbols. The symbols are formed and exchanged at the same time as the use of symbols in three levels, namely mind, self and society in symbolic interaction between mentally disabled students and teachers in special schools. The purpose of this study was to determine the use of mental retardation students and teachers in Special Schools. Descriptive qualitative research methods to explain phenomena accurately about existing facts. Data collection techniques through observation and in-depth interviews. Tunagrahita Teachers and Students in Special Schools become key informants in research, parents and closest friends become supporting informants. Data analysis technique is done by presenting data from Creswell. The theoretical foundation used in the research of Symbolic Interactionism from Mead. The results showed that the use of symbols in the mind, self and society level had an important role in the process of using symbols (manipulation and consumption) in the process of symbolic interaction. The conclusion of the research is the process of using symbols influenced by three levels of symbolic interaction, namely mind, self and society. Symbolic interaction at the level of society shows different levels according to the social and cultural background of students. Agreements that are built through symbolic interactions between teachers and students help students understand and understand social structures at school and at home, so they can constrain how they act and behave to suit other individuals.
El impacto de la Revolución Rusa en Uruguay (1917-1923)
Authors: Caetano Gerardo
Published: February 2021

Las consecuencias de los grandes procesos y acontecimientos de la historia universal (como es el caso de la Revolución Rusa) y su recepción específica por parte de los países de América Latina no ha sido un tema especialmente considerado por nuestras historiografías nacionales. El presente artículo procurará analizar su impacto en el universo político cultural uruguayo, comunistas, socialistas y anarquistas, pero también en los actores dominantes en el escenario político: el batllismo y los conservadores.
Cuestión agraria y políticas públicas en torno a la propiedad de la tierra durante los gobiernos peronistas (1946/1955;1973/1976). Propuestas, estrategias y alcances
Authors: Lazzaro Silvia
Published: February 2021

El objetivo del artículo es el análisis de las políticas públicas agrarias durante los gobiernos peronistas, centradas en la propiedad y tenencia de la tierra, en el período inmediatamente posterior a la posguerra y los primeros años de la década de 1970.Las mismas respondieron, en cada caso, a situaciones internas e internacionales disímiles, con fuertes tensiones sociales y políticas diversas, pero atravesadas por procesos conflictivos en torno a la redistribución, lo que generó disputas continuas y situaciones de inestabilidad; siempre en el marco de un capitalismo de Estado que implica la posibilidad de reproducción de condiciones favorables para el desarrollo de las fuerzas productivas bajo modalidades capitalistas de producción.
Un ciclo de canciones federales Las representaciones de Rosas y su época en la música popular de la primera mitad del siglo XX
Authors: Pankonin Leandro
Published: February 2021

En el presente artículo analizaremos las representaciones sobre la figura de Rosas y su época, producidas desde la música popular, entre fines de los años veinte y la década de 1940. Trabajaremos en particular el ciclo de canciones federales, que tuvo por figura central –aunque no exclusiva– a Ignacio Corsini. A partir de su análisis buscaremos profundizar en la manera en que pudieron haber interactuado los imaginarios nacionales, la música popular y el problema de los usos del pasado durante ese ciclo. En particular, buscaremos integrar este repertorio de canciones, dado lo prolífico y popular que fue, en una mirada integral sobre la manera en que aquella sociedad pudo haber construido sus representaciones sobre la época de Rosas.