bluuebunny/crossref_metadata_2025 huggingface dataset:
Polyglandular Autoimmune Syndrome Triggered after CTLA-4 and PD-1L Immunotherapy Treatment
Authors: Fernández-Morera Juan Luis , Renilla González Alfredo , Calvo Rodríguez Carmen Elena , Romano-García Judit
Published: January 2021

Background: CTLA-4 and PD-1L are novel immune checkpoint targets for cancer treatment with specific side effects such as autoimmune diseases. Less frequently, the presence of several autoimmune diseases in the same patient has been described. In this communication, we illustrate the case of a 45-year-old patient with a previous diagnosis of advanced cancer that, after starting treatment with this immunotherapy, developed in the following months autoimmune diabetes, lymphocytic hypophysitis, and a Hashimoto thyroiditis in an abrupt and intense manner that would correspond to an autoimmune polyglandular disease. Discussion: The activation of autoimmunity and associated diseases is increasing in parallel with augmented indication of these immunotherapeutic treatments in cancer patients. A closer follow-up of these patients could be necessary for an optimal approach to this type of pathology. Conclusions: Different autoimmune diseases can converge in the same patient when immunotherapy for cancer is indicated to boost immune response against tumor, caused by altering immune tolerance.
Prediction of Postoperative Complications for Patients of End Stage Renal Disease
Authors: Jeong Young-Seob , Kim Juhyun , Kim Dahye , Woo Jiyoung , Kim Mun Gyu , Choi Hun Woo , Kang Ah Reum , Park Sun Young
Published: January 2021

End stage renal disease (ESRD) is the last stage of chronic kidney disease that requires dialysis or a kidney transplant to survive. Many studies reported a higher risk of mortality in ESRD patients compared with patients without ESRD. In this paper, we develop a model to predict postoperative complications, major cardiac event, for patients who underwent any type of surgery. We compare several widely-used machine learning models through experiments with our collected data yellow of size 3220, and achieved F1 score of 0.797 with the random forest model. Based on experimental results, we found that features related to operation (e.g., anesthesia time, operation time, crystal, and colloid) have the biggest impact on model performance, and also found the best combination of features. We believe that this study will allow physicians to provide more appropriate therapy to the ESRD patients by providing information on potential postoperative complications.
Machine Learning Techniques for Hypoglycemia Prediction: Trends and Challenges
Authors: Mujahid Omer , Contreras Ivan , Vehi Josep
Published: January 2021

(1) Background: the use of machine learning techniques for the purpose of anticipating hypoglycemia has increased considerably in the past few years. Hypoglycemia is the drop in blood glucose below critical levels in diabetic patients. This may cause loss of cognitive ability, seizures, and in extreme cases, death. In almost half of all the severe cases, hypoglycemia arrives unannounced and is essentially asymptomatic. The inability of a diabetic patient to anticipate and intervene the occurrence of a hypoglycemic event often results in crisis. Hence, the prediction of hypoglycemia is a vital step in improving the life quality of a diabetic patient. The objective of this paper is to review work performed in the domain of hypoglycemia prediction by using machine learning and also to explore the latest trends and challenges that the researchers face in this area; (2) Methods: literature obtained from PubMed and Google Scholar was reviewed. Manuscripts from the last five years were searched for this purpose. A total of 903 papers were initially selected of which 57 papers were eventually shortlisted for detailed review; (3) Results: a thorough dissection of the shortlisted manuscripts provided an interesting split between the works based on two categories: hypoglycemia prediction and hypoglycemia detection. The entire review was carried out keeping this categorical distinction in perspective while providing a thorough overview of the machine learning approaches used to anticipate hypoglycemia, the type of training data, and the prediction horizon.
A Smart Biometric Identity Management Framework for Personalised IoT and Cloud Computing-Based Healthcare Services
Authors: Farid Farnaz , Elkhodr Mahmoud , Sabrina Fariza , Ahamed Farhad , Gide Ergun
Published: January 2021

This paper proposes a novel identity management framework for Internet of Things (IoT) and cloud computing-based personalized healthcare systems. The proposed framework uses multimodal encrypted biometric traits to perform authentication. It employs a combination of centralized and federated identity access techniques along with biometric based continuous authentication. The framework uses a fusion of electrocardiogram (ECG) and photoplethysmogram (PPG) signals when performing authentication. In addition to relying on the unique identification characteristics of the users’ biometric traits, the security of the framework is empowered by the use of Homomorphic Encryption (HE). The use of HE allows patients’ data to stay encrypted when being processed or analyzed in the cloud. Thus, providing not only a fast and reliable authentication mechanism, but also closing the door to many traditional security attacks. The framework’s performance was evaluated and validated using a machine learning (ML) model that tested the framework using a dataset of 25 users in seating positions. Compared to using just ECG or PPG signals, the results of using the proposed fused-based biometric framework showed that it was successful in identifying and authenticating all 25 users with 100% accuracy. Hence, offering some significant improvements to the overall security and privacy of personalized healthcare systems.
Modeling and Analysis of System Error for Highly Curved Freeform Surface Measurement by Noncontact Dual-Axis Rotary Scanning
Authors: Miao Li , Zhu Linlin , Fang Changshuai , Yan Ning , Yang Xudong , Zhang Xiaodong
Published: January 2021

Profile measurement is a key technical enabler in the manufacturing of highly curved freeform surfaces due to their complex geometrical shape. A current optical probe was used to measure nearly rotary freeform surfaces with the help of one rotation axis, because the probe needs to measure along the normal vector of the surface under the limitation of the numerical aperture (NA). This kind of measuring system generally has a high cost due to the high-precision, multi-axis platform. In this paper, we propose a low-cost, dual-axis rotation scanning method for a highly curved freeform surface with an arbitrary shape. The optical probe can scan the surface profile while always keeping consistent with the normal vector of the measuring points with the help of the double rotation axis. This method can adapt to the changes in curvature in any direction for a highly curved freeform surface. In addition, the proposed method provides a system error calibration technique for the rotation axis errors. This technique can be used to avoid the dependence of the measuring system on the high-precision platform. The three key system errors that affect the measurement accuracy such as installation error of the B-axis, A-axis, and XZ perpendicularity error are first analyzed through establishing an error model. Then, the real error values are obtained by the optimal calculation in the calibration process. Finally, the feasibility of the measurement method is verified by measuring one cone mirror and an F-theta mirror and comparing the results to those obtained using commercial equipment. The maximum measurable angle of the system is ±90°, the maximum measurable diameter is 100 mm, and the measurement accuracy of the system reaches the micron level in this paper.
The Spectral X-ray Imaging Data Acquisition (SpeXIDAQ) Framework
Authors: Van Assche Frederic , Vanheule Sander , Van Hoorebeke Luc , Boone Matthieu N.
Published: January 2021

Photon counting X-ray imagers have found their way into the mainstream scientific community in recent years, and have become important components in many scientific setups. These camera systems are in active development, with output data rates increasing significantly with every new generation of devices. A different class of PCD (Photon Counting Detector) devices has become generally available, where camera data output is no longer a matrix of photon counts but instead direct measurements of the deposited charge per pixel in every frame, which requires significant off-camera processing. This type of PCD, called a hyperspectral X-ray camera due to its fully spectroscopic output, yet again increases the demands put on the acquisition and processing backend. Not only are bandwidth requirements increased, but the need to do extensive data processing is also introduced with these hyperspectral PCD devices. To cope with these new developments the Spectral X-ray Imaging Data Acquisition framework (SpeXIDAQ) has been developed. All aspects of the imaging pipeline are handled by the SpeXIDAQ framework: from detector control and frame grabbing, to processing, storage and live visualisation during experiments.
Dual UV-Thermal Curing of Biobased Resorcinol Epoxy Resin-Diatomite Composites with Improved Acoustic Performance and Attractive Flame Retardancy Behavior
Authors: Nguyen Quoc-Bao , Vahabi Henri , Rios de Anda Agustín , Versace Davy-Louis , Langlois Valérie , Perrot Camille , Nguyen Vu-Hieu , Naili Salah , Renard Estelle
Published: January 2021

This study has developed novel fully bio-based resorcinol epoxy resin–diatomite composites by a green two-stage process based on the living character of the cationic polymerization. This process comprises the photoinitiation and subsequently the thermal dark curing, enabling the obtaining of thick and non-transparent epoxy-diatomite composites without any solvent and amine-based hardeners. The effects of the diatomite content and the compacting pressure on microstructural, thermal, mechanical, acoustic properties, as well as the flame behavior of such composites have been thoroughly investigated. Towards the development of sound absorbing and flame-retardant construction materials, a compromise among mechanical, acoustic and flame-retardant properties was considered. Consequently, the composite obtained with 50 wt.% diatomite and 3.9 MPa compacting pressure is considered the optimal composite in the present work. Such composite exhibits the enhanced flexural modulus of 2.9 MPa, a satisfying sound absorption performance at low frequencies with Modified Sound Absorption Average (MSAA) of 0.08 (for a sample thickness of only 5 mm), and an outstanding flame retardancy behavior with the peak of heat release rate (pHRR) of 109 W/g and the total heat release of 5 kJ/g in the pyrolysis combustion flow calorimeter (PCFC) analysis.
Adhesion Behavior of PVD-coated Cutting Tools
Authors: Fábián Enikő Réka , Horváth Richard
Published: January 2021

Cutting with TiAlN or CrAlN tip PVD-coated tungsten carbide-based inserts manufactured by powder metallurgy, we found no significant difference in the wear behavior of inserts regardless of whether the insert was used in wet or dry conditions. We determined the adhesion properties of the coating layers with a scratch test and by Daimler–Benz test. On the tungsten-based carbide cutting tool, the thinner TiAlN coating showed slightly better adhesion than the thicker CrAlN coating.
Development Options for Coronary Stent Coatings
Authors: Izsó Izabella , Asztalos Lilla
Published: January 2021

In our research we investigated the effect of different surface qualities on the adhesion of polylactic acid coating on 316L steel. During the study, samples were electropolished and surface treated with aqua regia and Vilella reagent, and the coating was applied by dipping technology using a Yaskawa robot arm. Tribology tests were carried out to determine the adhesion, in addition to the force and friction conditions, the coating damage resulting from the measurements was also recorded. In addition to the coating adhesion assay, contact angle measurements were also performed. Based on our measurement results, it was found that compared to the three different surface treatment methods, the surface of the samples treated with Villella was more adherent to the polymer than to the conventional electropolished surface. In this case, the frictional force was also much lower than that of the polished specimens, therefore this surface treatment method may be suitable for improving the adhesion of the coating.
STUDY OF THE CHEMICAL INTERACTION OF GLASS FIBER WITH CEMENT HYDRATION PRODUCTS
Authors: Bondarenko N. , Bondarenko D. , Evtushenko E.
Published: January 2021

Reinforcement of concrete with fiberglass improves the performance properties of concrete. The object of the study is fiberglass concrete, where Portland cement or alumina cement is used as a binder, and silica fiberglass is used as a filler. The chemical and phase compositions of Portland cement and alumina cement have been studied. The influence of the products of hydration of Portland cement and alumina cement on the chemical resistance of glass fiber has been investigated. The phase composition of Portland cement and alumina cement after hydration is studied using X-ray phase analysis. It is revealed that the following phases are present in alumina cement: CaОAl2O3, MgОAl2O3, 12CaO•7Al2O3, 2CaO•Al2O3•SiO, the phase composition of Portland cement is Ca6Al2(SO4)3(OH)12•12H2O, Ca2,25(Si3O7,5(OH)1,5)•(H2O), Ca(OH)2, CaCO3. It has been found that when hydrated, Portland cement has a negative effect on fiberglass due to the presence of Ca(OH)2 in it. The phase composition of the alumina cement after hydration shows the absence of Ca(OH)2. The chemical composition of fiberglass is investigated using X-ray fluorescence analysis. The use of alumina cement when using non-alkali-resistant fiberglass in a composite material is substantiated. The study of the stability of fiberglass in the environment of cement drawing has been carried out. Studies have shown that KV-11 grade fiberglass interacted less with hydration products of alumina cement than with hydration products of Portland cement.
DRY MIXTURES AND MIXING EQUIPMENT FOR THEIR PRODUCTION
Authors: Fadin Y. , Shemetova O.
Published: January 2021

Today’s economic situation creates conditions for revising the existing base of materials and raw materials in construction, as well as for transforming and using it in the future. One of the ways to achieve this goal is the creation of new types of building materials, more effective and low in the price category compared to the classic ones. Dry building mixtures belongs to such materials. The high quality of dry building mixes is guaranteed by the stability of their composition and the properties of the ingredients used. Saving time when using high-quality dry building mixes will allow to get an irreproachable end result. A necessary component in the manufacture of dry building mixtures is the mixing process, which includes the preparation of raw materials, dosing and the distribution of chemical additives. The main indicator of the quality of the finished product in the production of dry mixes is its uniformity. Therefore, special attention is paid to the mixing section in the production line. The variety of bulk materials and their properties contributes to the creation of various types of mixers for high-quality mixing of components. The article discusses the history of the emergence of dry building mixes and mixing equipment for production.
RELIABILITY OF QUALITY CONTROL OF BUILDING MATERIALS AND PRODUCTS
Authors: Loganina V.
Published: January 2021

The article deals with the issues of reliability of quality control of building materials and products. The structural diagram of the reliability of control of building materials is presented as a combination of series-connected technological operations. The purpose of the work is to assess the regulatory security of quality control of the production of building materials and products. The block diagram of quality control of concrete blocks for basement walls is presented. On the example of concrete blocks for basement walls, an assessment of the normative provision of product quality indicators is given. It has been established that the quality assurance of concrete blocks for FBS basement walls if all production parameters and quality indicators meet the requirements of regulatory documents and the condition: the mathematical expectation is in the middle of the product tolerance field and ± 3σ in the tolerance field is 0.9576, and the probability the appearance of marriage - 4.238%. The influence of the spread of indicators on the quality assurance is considered. It is found that with an increase in the value of the standard deviation to a value that is within the tolerance range of ± 2.5σ, the quality assurance decreases and amounts to 0,8092, and the probability of the appearance of defects is 19.08 %. It is shown that the application of the Six Sigma methodology at the enterprise will contribute to improving the quality of products
MANSIONS AND RESIDENTIAL BUILDINGS OF NOVOCHERKASSK 1900–1910
Authors: Ivanova-Ilyicheva A. , Orekhov N.
Published: January 2021

Mansions and individual residential houses of the early XX century form the basis of the historical center of Novocherkassk. The building of the city harmoniously combines features of traditional Cossack housing and adherence to the capital's architectural fashion, imitation of St. Petersburg. The history of the formation of the city, the social structure of the population, economy and culture determined the features of its architecture. In preparing the article, the methods of field and historical archival research, comparative analysis of works and their details, the method of analogies are used. A comprehensive analysis of typical objects – the mansion of G.M. Salnikov, the Shamarins' mansion, the house of the ataman A.V. Samsonov, residential buildings of the military master V.A. Ratchenkov and the сossack I.A. Suslova. The space-planning, compositional, architectural and artistic features of Novocherkassk mansions and residential buildings in the 1900–1910 s are identified. The authors present the patterns of location of two types of housing in the structure of the city. The tendencies of the Art Nouveau style in the mansions are revealed. A comparative analysis of the functional planning organization and artistic-figurative solution of the Cossack kuren and the city dwelling house is carried out. The study shows the influence of two trends on the residential architecture of Novocherkassk in 1900–1910 – the capital's professional design practice and the local folk tradition.
ACOUSTIC COMFORT OF THE ROOM AS ONE OF THE FORMATION FACTORS OF THE ENVIRONMENTAL SPACE
Authors: Tarasenko V. , Samoilova A. , Mosienko A.
Published: January 2021

The formation of the environment of the classroom is to create a comfortable environment that allows to fully implement the training function. When performing training sessions, one should focus not only on the functions of a specific audience, but also take into account the configuration, interior elements, various options for placing furniture and equipment, and the possibility of staying with low-mobility groups of students. The main components of acoustic comfort that affect the nature of sound propagation in the room are considered. Variants of changing unfavorable acoustic characteristics, using modern acoustic plasters, changing the function and arrangement of furniture corresponding to it are proposed. The calculation of the reverberation time of the classroom is made in accordance with the proposed concept of interior design. The issue of accessibility of educational space for people with movement and hearing disabilities is quite relevant at the present time. The result of solving this problem is a variant of furniture placement that allows to place two seats for specialized chairs. Based on the results of the analysis of the acoustic mode of the room, variants of the design project of the diploma design classroom are made using interactive technologies. The results of a theoretical analysis of the placement of furniture in the classroom shows its inaccessibility for use by people with disabilities. In addition, modern requirements for the placement of furniture provides a number of proposals to change the content of the classroom and the placement of educational furniture and equipment. The subsequent calculation of the reverberation time makes it possible to offer new modern materials for finishing the room, taking into account the change in function. Acoustic comfort is provided by a set of materials and furniture placement techniques and allows to conduct training, including in a remote format. It will also provide students with the necessary educational equipment and improve the level of training of specialists.
LITERATUR REVIEW EVALUASI PEMBELAJARAN IPS
Authors: Juliana Nurlita
Published: January 2021

Karya ilmiah yang di reviewAnis, M. Z. A., Putro, H. P. N., Susanto, H., & Hastuti, K. P. (2020). Historical Thinking Model in Achieving Cognitive Dimension of Indonesian History Learning. PalArch's Journal of Archaeology of Egypt/Egyptology, 17(7), 7894-7906.
KONTROVERSI JFC (JEMBER FASHION CARNAVAL) KE-18 DALAM DISKURSUS MEDIA DAN PEMIKIRAN TOKOH AGAMA DI JEMBER
Authors: Ningsih Bunga Surawijaya
Published: January 2021

The 18th JFC (Jember Fashion Carnaval) in 2019 chose Cinta Laura Kiehl as its grand ambassador. The event, which is held in every year never escapes from the media spotlight. One of them happened in 2019. this event made by Dynand Fariz which is caused controversy among public and the mass media. This event invited polemics to the response of MUI Jember,the management of Muhammadiyah Jember, and the chief of FPI East Java since the clothes that is worn by cinta laura. this phenomenon, such as in media Bangsaonline.com and Potrerjember.com which are East Java media and online media that contain the most news about the 18th JFC controversy in 2019. In this study, researchers used William A. Gamson's framing analysis method and Andre Modiglani, which emphasized to the symbolic form through figurative and rhetoric which indirectly directs the news which forms an image from certain aspects in the public. In addition, it also contains of the views of religious leaders in Jember. The result was that Bangsaonline.com andotretjember.com looked shy when it reportes the controversy news. However, in the packaging of the news, words, terms, phrases, sentences, facts, paragraphs, and images used by online media tend to highlight images that indulge in genitals and violate religious values.
The effect of stakeholder on firm value and environmental performance as intervening variable
Authors:   Universitas Sebelas Maret, Surakarta, Suhardjanto Djoko , Santosa Sigit ,   Universitas Sebelas Maret, Surakarta, Fitrianto Suratno Tri ,   Universitas Sebelas Maret, Surakarta, Fatmawati Rini ,   Universitas Sebelas Maret, Surakarta
Published: January 2021

Purpose: This study aimed to understand the relationship between stakeholder and firm value with environmental performance as the intervening variable. The study was conducted on companies listed in Indonesia Stock Exchange and listed in the PROPER program during 2016 and 2017. The stakeholder variables in this study consist of managerial ownership (manager), consumer, and employee. Research methodology: The samples were determined using purposive sampling with a total of 131 companies and using path analysis method as an expansion of regression analysis. Result: The result is managerial ownership, consumer, and employee do not affect firm value directly. Managerial ownership has a positive and significant effect on firm value through environmental performance. The consumer has a significant and negative effect on the firm value through environmental performance and employee has a significant and negative effect on the firm value. Limitation: The sample is limited for two years period and adjusted R2 is 21.5%. Contribution: This study can identify variables that affect firm value, especially: manager, consumer, employee and environmental performance. Keywords: Firm value, Stakeholder, Environmental performance
DEVELOPMENT OF THE SUSTAINABLE NEED-MOTIVATION ATTITUDE OF STUDENTS TO PHYSICAL AND SPORT ACTIVITIES
Authors: Lutchenko Nikolay , Perevoznikova Nataliya , Grigorev Nikolay
Published: January 2021

The aim of the research is to substantiate the place and role of the need-motivation factor in the structure of personal professional activity and its influence on the development of value orientation in the process of physical culture and sport activities (PCSA).
Methods and organization of the research. In our research we used the following methods: theoretical analysis of literary sources and educational programs of universities, conversation, questionnaires, and pedagogical observations. The study was conducted on the basis of the Saint Petersburg Humanitarian University of Trade Unions during the academic year. The survey involved 100 students of 2nd year of study.
Research results. The research revealed needs, main motives and factors determining the degree of students' involvement in PCSA. The authors demonstrated the role of communication in solving educational problems. The analysis of literary sources revealed the need-motivation attitude of students to PCSA. We have found that one of the reasons for the low level of physical fitness and poor health is the lack of stable motives, interests and needs in systematic PCSA. The issue of improving physical fitness of students requires a well-grounded approach forwarding the educational process towards the comprehensive development of the personality on the basis of a motivational-value attitude to PCSA.
Conclusion. Personal demand for the PCSA determines its focus on achieving a goal and acquires a motivation factor when it is recognized by the subject as an opportunity to satisfy a desire. Sustainability of the motivational-value attitude of students to PCSA is largely ensured by the use of stimulating organizational and methodological measures in the educational process. The use of visuals and electronic resources in combination with summing up the results of sport events and rewarding the best sport teams and athletes contribute to enhancing students' motivational-value attitude to PCSA.
MYTHOLOGY AND REALITY OF OLYMPIC AGON OF ANCIENT GREECE IN THE ROMAN ERA
Authors: Rekutina
Published: January 2021

The aim of the research: to identify changes in the nature of relationship between mythological, religious and social aspects in the sphere of agonistics in Ancient Greece in the Roman Era. Methods and research: Analysis of literature and written sources on the history of ancient agonistics. The result of the study is the determination of the specific traits of agonal traditions of Ancient Greece and Ancient Rome. The article explores the sacral and secular aspects of the traditions and rules of antique agon. The Author shows a change in their ratio in Ancient Greece in the Roman Era. The paper focuses on the process of transformation of the sacral and secular content of agonistics and a variety of agon in Ancient Greece in the Roman Era, which is characterized by the clash of Hellenic and Roman agonal traditions. One of the most significant phenomena in the ideological life of that period was the cult of the Emperor, which was the official political religion of the Roman Empire. The Emperor’s cult with agon as one of the rituals became widespread in the western and eastern provinces including Greece. Greece had the status of "Achaea Roman Province" at that time. The Author describes the events that took place in Olympia and other religious centers of Ancient Greece at that time. Conclusion: Agonist features of the period were determined by changing the ratio of religious and social components of agonistics and transforming agony as a religious ritual into a spectacle that was widely used for political purposes.
PSYCHOLOGICAL AND PEDAGOGICAL ASPECTS OF THE PHYSICAL EDUCATION TEACHING QUALITY AT THE UNIVERSITY
Authors: Pokrovskaia Tatyana , Yusupov Rinat , Titova Elena
Published: January 2021

Purpose. The article reveals the patterns of successful transfer of socio-pedagogical experience from a teacher to students, the pedagogical influence on personal development and instructional importance in the educational process. Being a way of organizing educational activities, learning is the most reliable way to obtain a systematic education. It contributes to the assimilation of knowledge, skills and abilities and development of personal qualities that help a person to adapt to external conditions and express one’s personality. The quality of administration of educational process has a big impact on the development of creative and independent mentality of students, acquisition of professional competencies for achieving a high level of proficiency to withstand competitiveness in the labor market and develop the potential for self-development and self-education. The teacher of physical culture is fully responsible for ensuring the modern administration of the educational process and social activities of the high quality to train qualified specialists with theoretical and applicable knowledge, skills and competencies.
Research methods and organization. The authors use the methods of questionnaire survey, pedagogical observation and comparative assessment to reveal the psychological and instructional aspects of the quality of physical education at the university, as well as students' interest in Physical education as university subject.
Research results. The research resulted in the identification of students’ attitude to the quality of the educational process, their satisfaction with the quality of provided education, and the quality of the administration of physical and sports activities.
Conclusion. We have substantiated the significance of psychological and pedagogical approach used by educators at physical education classes. It is especially relevant in modern conditions for improvement of the quality of educational process through the attitude of students to the Physical education and sports subject.
EDUCATIONAL POTENTIAL OF SPORTS ENVIRONMENT IN EDUCATIONAL ORGANIZATIONS
Authors: Manzheley Irina , Chayun Danil
Published: January 2021

Relevance. The essential changes occurring in the modern world after a long home confinement have contributed to the public awareness of the importance of physical activity and communication for "preserving a person as a biosocial structure" (V.S. Stepin). In this context, the implementation of the federal project "Sport is the Way of Life" acquired new meanings related to the upbringing of the younger generation in Russia.

The information society imposes the requirements of predictability and forward-looking development on additional education as a socio-genetic institution, in order to prepare a person for the future.

The purpose of the research is to study the social and psychological characteristics of subjects and the educational potential of the sports environment of educational organizations implementing sports training programs in biathlon and cross-country skiing in the Tyumen region.

The results and scientific novelty of the research. This paper aims to show new data on the social and psychological difficulties and significant qualities of a child coach and an adolescent athlete, taking into account four subjects (а manager, а coach, a parent, and an adolescent-athlete), the attitude towards doping, and the quality of sports services. It will contribute to the formation of regional and federal information bank of data on social and psychological determinants of the youth sports development. We defined the critical points, support positions and growth points for the educational potential of sports environment in educational organizations implementing sports training programs in biathlon and cross-country skiing in the Tyumen region.
SUMMER TRAINING CAMPS AS A FORM OF SKI JUMPING TRAINING
Authors: Fendel Tatyana , Zubkov Dmitry
Published: January 2021

The research purpose is to theoretically substantiate, develop, experimentally test and measure the impact of summer training camps with simultaneous advanced coach training.

The research methodology and organization. The research subject was summer training camps with simultaneous advanced coach training, in the framework of the grant program of the Ministry of Sports of the Russian Federation. The program title is ‘Fly to your Dream!’ Sports-educational cluster - the innovative form of the sports training system enhancement’. The training camp program included ski jumping training, advanced coach training, medical and pedagogical observations, as well as educational and leisure activities for the athletes attending the ‘Snezhinka’ [‘Snowflake’] Federal Winter Sports Training Center based at Tchaikovsky State Physical Education Institute.

The research results. Over 4.5 million viewers watched a series of «Fly to your Dream» education videos. 65 coaches attended a series of online training seminars in the framework of advanced training courses. 84 flying skiers aged under 14 years took part in the first International ‘Fly to your dream!’ online festival. The overwhelming majority of the surveyed project participants noted the importance of such activity as a tool for popularization and promotion of ski jumping and biathlon skiing (265 people), and as a form of training process (213 people).

Сonclusion. The authors conclude that the format suggested for the training process can be recommended for biathlon skiers and other athletes.
ЗАКОНОМЕРНОСТИ НОМИНАЦИИ ЭТНИЧЕСКИХ ИМЕН
Authors: MYNBAYEV Nurlan
Published: January 2021

Процесс формирования и функционирования этнических именв статье рассматривается с целью установить закономерности их номинации. В свое время Ф. Энгельсом было высказано мнение об отсутствии каких-либо правил номинации этнонимов. В связи с диктатом идеологии и догматическим восприятием высказываний деятелей марксизма, такая точка зрения стала доминирующей. Кроме того, в эпоху торжества идей коммунизма, исследование этнонимов стало рассматриваться как интерес к пережиткам прошлого, что тормозило развитие ономастики, в частности этнонимики и этимологии этнонимов. Тем не менее,еще в тридцатые годы прошлого столетия была обозначена, затем позже сформулирована закономерность типологической универсалии в этнонимике. Критическое изучение проблемы позволило детально описать эту основную закономерность номинации и выявить две ее существенные особенности, такие как позитивность и негативность семантики этнонимов, которые сами по себе уже являются закономерностями номинации этнонимов. В дальнейшем на основании последних достижений науки был установлен еще ряд закономерностей номинации этнонимов. Объектом исследования явились в основном тюркские этнонимы. Материал рассмотрен в синхронии, диахронии,а также в пантопохронии. Стратегия изучения строиласьна констатации концептообразующих выводов, которые формулируются в качестве закономерностей номинации этнонимов: 1) этноним — факт языка и единица целостной этнонимической системы; 2) этнонимообразование подчиняется словообразовательным моделям того или иного языка. В процессе историко-лингвистического анализа этнонимов был выстроен алгоритм выявления этноморфем, выражающих универсальную семантику этнических имен. Параллельное рассмотрение этнической и этнонимической системы в пантопохронии, а также скрупулезное изучение проблем типологической универсалии в этнонимике дало положительные результаты, подтвержденные в процессе интегрированного исследования лингвистического и экстралингвистического содержания этнических имен.
Event-triggered attack detection and identification in power-electronics-based DC microgrid
Authors: Gong Sicheng
Published: January 2021

This paper proposes a novel event-triggered attack detection mechanism for converter-based DC microgrid system. Under a distributive network framework, each node collects its neighbours' relative data to regulate its own output for local stabilization. Without power line current data, hardly can an agent directly identify the source of unexpected power flow, especially under an organized attack composed of voltage variations and corresponding deceptive messages. In order to recognize traitors who broadcast wrong data, target at system distortion and even splitting, an efficient attack detection and identification strategy is mandatory. After the attack detector is triggered, each relative agent refuses to trust any received data directly before authentication. Through proposed two-step verification by comparing theoretical estimated signals with received ones, both self sensors and neighbour nodes would be inspected, and the attacker was difficult to hide himself. Through simulation on SIMULINK/PLECS and hardware experiments on dSpace Platform, the effectiveness of proposed detection algorithm has been proved.
The physiology of ketosis and the ketogenic diet
Authors: Leonard TGA
Published: January 2021

Ketones are an important fuel source for the body during periods of starvation and are readily used by the brain, the heart, and skeletal muscle. Ketones may also be produced in response to certain diets. Interest in the use of a diet high in fat and low in carbohydrates in order to induce a state of ketosis has increased in recent years. This review will cover the physiology of ketosis and examine the effects of the ketogenic diet.
The public health ethics framework and implications for COVID-19
Authors: Lundgren AC , Etheredge HR
Published: January 2021

The current COVID-19 pandemic may require a shift in our ethical thinking – away from the widely endorsed framework of patientcentred care towards “public health ethics”. At its core, public health ethics works towards the welfare of a majority in society, and as such, it is not usually applied to individual patients, but rather to a collective (for instance, society as a whole). This may call on us to redirect our efforts away from tirelessly promoting the autonomy of individual patients, towards the welfare of patients as a collective. During COVID-19, this confers a duty not only to existing patients under our care, but also to patients who may present with COVID-19.
Calcium homeostasis
Authors: Manitshana N
Published: January 2021

Calcium and phosphorus are the most abundant minerals in the body. An adult body contains over 1 kg of calcium and it has various functions throughout the body. The average plasma concentration of calcium is about 2.5 mmol/l. The intracellular concentration of calcium is approximately 100 nmol/ml. The control of both intracellular and extracellular calcium concentrations is vital.
pKa and Ka (Acid dissociation constant)
Authors: Manjooran G
Published: January 2021

pKa of a drug is the pH at which 50% of the drug is ionised and 50% is not ionised/unionised.

The pKa is specific for each drug and these properties determine how a drug can be administered, the speed of absorption as well as speed of excretion by the kidneys.
Pituitary gland and growth hormone
Authors: Mashinini MMA
Published: January 2021

The pituitary gland (PG) is said to be a “master” endocrine gland and through its tropic hormones influences other endocrine glands to secrete hormones that have a variety of effects on body systems. Growth hormone (GH) is a pituitary gland hormone that has direct and indirect effects produced by somatotrophs in early fetal life. It is essential for normal postnatal growth and has diverse effects across multiple physiological systems. The somatotrophic axis is made predominantly of GH, insulin-like growth factor 1 (IGF-1) and other factors regulating growth. This review summarises the relevant anatomical relationships of the PG, the basic aspect of GH physiology which includes mechanism of action (MOA), regulation and secretion and a direct and indirect action of GH through IGF-1, an important mediator of most of the peripheral action of GH.
The right ventricle
Authors: MotMotshabi Chakane P
Published: January 2021

The healthy right ventricle (RV) has a thin-walled structure compared to the thick-walled left ventricle (LV). It has a complex shape that appears crescentic when viewed in cross section and triangular when viewed from the side.
DEVELOPMENT OF A PROCEDURE FOR DESIGNING DIGITAL AUTOMATES WITH MEMORY ON FPGA
Authors: Пирогов А.А. , Пирогова Ю.А. , Гвозденко С.А. , Шардаков Д.В. , Сёмка Э.В.
Published: January 2021

Программируемые логические интегральные схемы (ПЛИС) - это настраиваемые интегральные схемы, логика которых определяется программированием. ПЛИС производятся полностью в готовом виде, т.е. относятся к стандартной продукции, что сопровождается известными преимуществами - массовым производством и снижением затрат. Благодаря регулярной структуре ПЛИС реализованы с уровнем интеграции, близким к максимально эффективному. Использование ПЛИС позволяет получить устройства, которые могут менять конфигурацию, подстраиваясь под конкретную задачу, благодаря своей гибко изменяемой, программируемой структуре. При разработке сложных устройств в качестве компонентов для проектирования могут использоваться готовые блоки: IP-ядра или сложно-функциональные блоки (СФ-блоки). Применение программных СФ-блоков позволяет максимально эффективно использовать их в итоговом проекте, таким образом во многом снижаются затраты на проектирование. Цель работы - изучение методики описания триггеров на языке VHDL, применения встроенного схемного редактора Active HDL для формирования структур различных цифровых автоматов и верификации моделей на логическом уровне. В данном исследовании рассмотрены схемы генераторов псевдослучайных последовательностей, которые находят применение в задачах криптографии, где свойства программируемой структуры ПЛИС достаточно актуальны

Programmable logic integrated circuits (FPGAs) are custom integrated circuits whose logic is defined by programming. FPGAs are manufactured completely off-the-shelf, i.e. belong to standard products, which is accompanied by well-known advantages - mass production and cost reduction. Due to the regular structure, FPGAs are implemented with a level of integration close to the most efficient one. The use of FPGAs makes it possible to obtain devices that can change configuration, adjusting to a specific task, thanks to their flexible, programmable structure. When developing complex devices, ready-made blocks - IP-cores or complex-functional blocks (SF blocks) - can be used as components for design. The use of software SF blocks allows you to use them as efficiently as possible in the final project, largely reducing design costs. The purpose of the work is to study the technique of describing triggers in the VHDL language, using the built-in Active HDL schematic editor to form the structures of various digital automata and verifying models at the logical level. In this study, we considered schemes of pseudo-random sequence generators, which are used in cryptography problems, where the properties of the programmable FPGA structure are quite relevant
THE EFFECT OF FINANCIAL PERFORMANCE ON SHARE RETURN WITH COMPANY SIZE AS MODERATED VARIABLES
Authors: Anna Christin Silaban
Published: January 2021

The purpose of this study are as follows: 1) To examine the effect of ROA on Stock Returns; 2) To assess the effect of CR on Stock Returns; 3) To assess the effect of DER on Stock Returns; 4) To examine the effect of PER on Stock Returns; 5) To assess the effect of PBV on Stock Returns; and 6) To assess the extent to which Company Size can moderate the relationship between ROA, CR, DER, PER, PBV and Stock Return. This type of research used in this study is a casual associative research (causal associative research). The population in this study are property, real estate, and building construction companies that are included in the Kompas 100 index which are listed on the Indonesia Stock Exchange during 2013-2018. Sample selection with purposive sampling method. The analytical method used to test the hypothesis is multiple regression analysis with the absolute difference test. The results showed that: 1) ROA has a positive effect on stock returns; 2) CR does not have a significant positive effect on stock returns; 3) DER has a positive effect on stock returns; 4) PER has a positive effect on stock returns; 5) PBV has no effect on stock returns; and 6) Company size is not able to moderate the relationship between ROA, CR, DER, PER, PBV with stock returns.

KEYWORDS: Return On Assets, Current Ratio, Debt to Equity Ratio, Price Earning Ratio, Price to Book Value, Company Size, Stock Return
Power Efficient GaN HEMT High Power
Amplifier Design Operating at 5-7GHz
Bandwidth
Authors: Hussain Syed Mudassir
Published: January 2021

For the next generation applications in mobile communication, radar and satellite communication we need the devices that can operate at high frequencies and high power with minimum power consumption. There is a growing importance in the recent years for the development of GaN transistors.This paper presents design of the power efficient GaN based high power amplifier operating in the bandwidth of 5GHz – 7GHz based on a 12 Watt Discrete Power GaN on SiC HEMT from TriQuint. In this manuscript the design of RF power amplifier, its stability, input and output matching impedance and performance for 5-7GHz is presented. Design and simulations of the power amplifier are carried out using Advanced Design System (ADS). Simulation results of device stability, gain and Power Added Efficiency (PAE) shows good accordance with the specifications and parameters of the device.In the design process, for better correlation in measurement and simulation results precision of passive element models are specially considered. In 1 dB compression point for the designed high power amplifier, the experiment and the simulation results show a Power Efficiency of 68%.
SOSIALISASI PERAN ORANG TUA DI MASA PANDEMIK COVID 19 DALAM PEMBELAJARAN DARING BAGI ANAK USIA SEKOLAH DASAR DESA CIKALONGSARI KARAWANG
Authors: Yayan Alpian
Published: January 2021

Kegiatan pengabdian kepada masyarakat ini bertujuan untuk mengetahui peran apa saja yang orang tua berikan selama mendampingi anak dalam kegiatan belajar di rumah pada anak usia Sekolah Dasar di masa pandemi Covid-19. Metode yang digunakan dalam kegiatan pegabdian kepada masyarakat ini melalui kegiatan yang dikemas secara workshop tentang peran orang tua di masa pandemic Covid-19 dalam pembelajaran daring bagi anak usia sekolah dasar, sedangakan yang menjadi khalayak sasarannya adalah para orang tua di Desa Cikalongsari Kecamatan Jatisari Kabupaten Karawang. Hasil kegiatan pengabdian kepada masyarakat ini memberikan pengetahuan dan pemahaman bagi orang tua dalam membantu, membimbing anak belajar secara daring di rumah dan memahami bagaimana pentingnya pengawasan bagi anak dalam proses pendidikan, sekaligus dapat merasakan bagitu berat tugas seorang guru dalam mendidik anak di sekolah.

Kata Kunci: peran orang tua, masa pandemi covid-19
Comparative characteristics of the therapeutic efficacy of methods of drug administration under the conjunctiva
Authors:   Chief physician, Veterinary Ophthalmologist, Voronezh Veterinary Hospital № 1, Voronezh, Russian Federation, Solomakhina L. A. , Argunov M. N. ,   Doctor of Veterinary Sciences, Honored Scientist of the Russian Federation, Professor of the Department of Therapy and Pharmacology, Voronezh State Agrarian University named after Peter I, Voronezh, Russian Federation
Published: January 2021

The assessment of the therapeutic efficacy of methods of subconjunctival injections of various groups of drugs for pathologies of the cornea and anterior choroid (with anterior uveitis) was carried out. In this article, we dwelt in detail on the indications, contraindications to subconjunctival injections, the list of necessary for this manipulation and injection techniques, possible complications and drugs that can be administered by this method.