bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of In-vitro Propagation and Organic Farming Cultivation Practices of Artemisia annua L. on the Enhancement of Artemisinin Yield
Authors: Agrawal Ankit , Sharma Anjana , Shukla Narmada P.
Published: March 2020

Background :

Artemisia annua is well known for its anti-malarial bio-active compound
artemisinin. Development of elite planting material of A. annua and its agro-technology can fulfill the
requirement of Artemisinin-based Combination Therapy (ACT) dosages worldwide.

Objectives:

To develop an efficient in-vitro propagation protocol for A. annua and assess the field performance
of in-vitro propagated plants for their growth and artemisinin yield.

Methods:

The in-vitro propagation protocol of A. annua was developed using the nodal segment in
four steps viz: initiation, multiplication, rooting and hardening. In-vitro propagated plants were transplanted
with open-pollinated seed raised plants in an experimental field trial having soil supplementation
of Farm Yard Manure (FYM), vermicompost and NPK.

Result:

Maximum 92% shoots were initiated in Murashige and Skoog medium (MS) with 0.44 μM
6-benzyl aminopurine (BA) and highest 281.33 ± 09.75 micro-shoots/inoculum obtained in MS with
15.54 μM BA. The maximum number of roots was found in MS with 100 mg/L activated charcoal
while 78.20% of plants survived in the sand: soil: vermicompost (1:1:1) mixture. The highest dry leaf
yield (6.37 t/ha) was observed in in-vitro propagated plants grown with vermicompost, while highest
artemisinin content (1.11 ± 0.10) and artemisinin yield (65.05 kg/ha) was found in the in-vitro propagated
plants grown with FYM after 120 days of transplantation.

Conclusion:

This study reports an efficient, cost-effective and rapid in-vitro propagation protocol for
A. annua as well as enhanced artemisinin yield through the cultivation of in-vitro propagated plants
using organic soil supplement inputs. This would lead to an increase in the production of artemisinin
yield and fulfill the demand of Artemisinin-based Combination Therapy (ACT).
FAMÍLIAS, MASCULINIDADES E RACIALIDADES NA ESCOLA: PROVOCAÇÕES QUEER E DECOLONIAIS
Authors: Caetano Marcio , Melgaço da Silva Junior Paulo , Silva Goulart Treyce Ellen
Published: March 2020

O presente artigo discute, a partir das contribuições dos Estudos Decoloniais e Queer, os modos pelos quais estudantes do 6º ano de uma escola pública da periferia de Duque de Caxias, cidade localizada na Baixada Fluminense, Região do Estado do Rio de Janeiro, construíram e vivenciaram seus arranjos familiares, ressignificando cotidianamente as expectativas sexuais e raciais, a maternidade e a paternidade. Com essa investigação, a partir do método da pesquisa-ação, objetivou-se problematizar as noções de família, trazendo à tona a necessidade de reconhecer outras possibilidades. Com os dados que subsidiaram a análise, produzidos nos encontros semanais da disciplina “Artes Visuais”, buscou-se questionar os currículos com vistas a interrogálos sobre os discursos que produziram modos de subjetivação e ensinaram formas heteronormativas, comple-mentares e assimétricas de projeção das identidades sexuais fortemente atravessadas pelas expectativas em torno à(s) masculinidade(s) negra(s).
TRANSNACIONALISMO NEGRO: A ENCRUZILHADA DE AMEFRICAN@S
Authors: Augusto Geri
Published: March 2020

Este artigo utiliza duas narrativas de jornadas pessoais de transna-cionalismo negro a partir dos escritos e das ideias de Lelia Gonzalez e Ella Baker, mulheres negras pensadoras ativistas, seminais e radicais, para refletir sobre a carga tripla enfrentada por trabalhadoras domésticas negras no Brasil e nos EUA. Consideram-se as ideiase formas de vida da aldeia contemporânea de quilombolas pescadores e pescadoras, visto do jardim de uma marisqueira, para refletir sobre o espaço de contribuição potencial e equitativo, a práxis e o pensamento, e as aberturas epistêmicas possíveis no universo acadêmico, quando conhecimentos marginalizados e multifacetados são postos. Utilizou-se os conceitos teóricos de Amefricanidade, interseccionalidade e afeto comum, bem como a noção de encruzilhada encontrada em muitas tradições culturais do pensamento Afrodescendente.
Prevalencia de endoparásitos y ectoparásitos en serpientes ex situ en Barranquilla, Colombia.
Authors: Duran Peñaranda Nazly Datniza , Franco Gutiérrez Monica , Guimarães Riva Henrique , Flórez Gelvez José
Published: March 2020

Objetivo. Identificar la prevalencia de endoparásitos y ectoparásitos en serpientes ex situ en la Fundación Botánica y Zoológica de Barranquilla. Materiales y métodos. Para esto se analizaron muestras de materia fecal y ectoparásitos de 2 colúbridos (Leptophis ahaetulla y Spilotes pullatus), 2 dipsadinos (Oxybelys aeneus y Thamnodynastes paraguanae) y 13 boidos (9 individuos de la especie Boa constrictor, 2 de Epicrates maurus y 2 de Eunectes murinus) utilizando los métodos de flotación en solución saturada de azúcar y observación directa. Resultados. Los resultados obtenidos mostraron que el 65% (11/17) de los animales evaluados fueron positivos a la presencia de parásitos, de los cuales el 91% (10/11) de los ejemplares pertenece a la familia Boidae presentando en su mayoría nematodos, mientras que en los dipsadinos se observaron principalmente protozoarios y los colúbridos resultaron negativos. Finamente como ectoparásitos se identificaron 2 especies de garrapatas (Amblyomma dissimile y Ornothodoros turicata) halladas en ejemplares de Boa constrictor, Epicrates maurus y Spilotes pullatus. Conclusiones. La identificación de las formas parasitarias en este trabajo representa una contribución para el conocimiento de los parásitos en serpientes ex situ en Colombia. Provee información para desarrollar medidas profilácticas y permite comparar los datos sobre las formas parasitarias encontradas con muestreos de estas especies en vida silvestre y bajo cuidados humanos.
Trends and Outcomes with Kidney Failure from Antineoplastic Treatments and Urinary Tract Cancer in France
Authors: Mansouri Imène , Alencar de Pinho Natalia , Snanoudj Renaud , Jacquelinet Christian , Lassalle Mathilde , Béchade Clémence , Vigneau Cécile , de Vathaire Florent , Haddy Nadia , Stengel Bénédicte ,   on behalf of the French REIN registry
Published: March 2020

Background and objectives

Cancer survival is improving along with an increase in the potential for adverse kidney effects from antineoplastic treatments or nephrectomy. We sought to describe recent trends in the incidence of kidney failure related to antineoplastic treatments and urinary tract cancers and evaluate patient survival and kidney transplantation access.

Design, setting, participants, & measurements

We used the French Renal Epidemiology and Information Network registry to identify patients with kidney failure related to antineoplastic treatments or urinary tract cancer from 2003 to 2015. We identified 287 and 1157 cases with nephrotoxin- and urinary tract cancer–related kidney failure, respectively. The main study outcomes were death and kidney transplantation. After matching cases to two to ten controls (n=11,678) with other kidney failure causes for age, sex, year of dialysis initiation, and diabetes status, we estimated subdistribution hazard ratios (SHR) of each outcome separately for patients with and without active malignancy.

Results

The mean age- and sex-adjusted incidence of nephrotoxin-related kidney failure was 0.43 (95% CI, 0.38 to 0.49) per million inhabitants and 1.80 (95% CI, 1.68 to 1.90) for urinary tract cancer–related kidney failure; they increased significantly by 5% and 2% annually, respectively, during 2006–2015. Compared with matched controls, age-, sex-, and comorbidity-adjusted SHRs for mortality in patients with nephrotoxin-related kidney failure were 4.2 (95% CI, 3.2 to 5.5) and 1.4 (95% CI, 1.0 to 2.0) for those with and without active malignancy, respectively; for those with urinary tract cancer, SHRs were 2.0 (95% CI, 1.7 to 2.2) and 1.1 (95% CI, 0.9 to 1.2). The corresponding SHRs for transplant wait-listing were 0.19 (95% CI, 0.11 to 0.32) and 0.62 (95% CI, 0.43 to 0.88) for nephrotoxin-related kidney failure cases and 0.28 (95% CI, 0.21 to 0.37) and 0.47 (95% CI, 0.36 to 0.60) for urinary tract cancer cases. Once on the waiting list, access to transplantation did not differ significantly between cases and controls.

Conclusions

Cancer-related kidney failure is slowly but steadily increasing. Mortality does not appear to be increased among patients without active malignancy at dialysis start, but their access to kidney transplant remains limited.
Clinical therapeutic efficacy of mesenchymal stem cells derived from adipose or bone marrow for knee osteoarthritis: a meta-analysis of randomized controlled trials
Authors: Han Xinxin , Yang Bo , Zou Fagui , Sun Jianbo
Published: March 2020

Aim:
This meta-analysis, only including randomized controlled trials (RCTs), was conducted to assess separately and compare the therapeutic efficacy of adipose-derived mesenchymal stem cells (ADMSCs) and bone marrow-derived mesenchymal stem cells (BMSCs) for knee osteoarthritis (OA) at the same follow-up time.
Methods:
Potential relevant researches were identified from PubMed, Web of Science, Embase, Cochrane Library and clinicaltrials.gov. The data, from clinical trials concentrating on knee OA treated with ADMSCs or BMSCs, were extracted and pooled for meta-analysis to compare the clinical outcomes of patients with knee OA in visual analog scale (VAS), Western Ontario McMaster Universities Osteoarthritis Index (WOMAC), Lysholm knee scale (Lysholm) and Tegner activity scale (Tegner).
Results:
Nine randomized controlled trials including a total of 377 patients met the inclusion criteria. This meta-analysis obtained the following results. First, the improvement of VAS scores was statistically significant after BMSCs treatment at 6-, 12- and 24-month follow-up compared with control groups (p < 0.01). In contrast, the improvement of WOMAC scores was of no statistical significance, but showed a positive trend with the prolongation of the follow-up time (6 months: mean difference [MD] = 6.51; 95% CI: -2.38 to 15.40; p = 0.15; 12 months: MD = -6.81; 95% CI: -13.94 to 0.33; p = 0.06). Lysholm scores presented a similar pattern (12 months: MD = 1.93; 95% CI: -11.52 to 15.38; p = 0.78; 24 months: MD = 8.94; 95% CI: 1.45 to 16.43; p = 0.02). Second, VAS and WOMAC scores of patients after ADMSCs treatment were significantly improved at any follow-up time (p ≤ 0.05). The improvement of Lysholm scores was of no statistical significance compared with control groups, although treatment outcome at 12-month follow-up was better than that at 24-month follow-up, which was debatable because only data of one clinical trial were pooled in the analysis (12 months: MD = 7.50; 95% CI: -1.94 to 16.94; p = 0.12; 24 months: MD = 5.10; 95% CI: -3.02 to 13.22; p = 0.22). Finally, by comparing the statistical results of VAS and WOMAC scores, it could be concluded that the therapeutic effect of ADMSCs on knee OA was more effective than that of BMSCs.
Conclusion:
This meta-analysis showed that regeneration with BMSCs or ADMSCs had a great application potential in the treatment of patients with knee OA, and ADMSCs tended to be superior to BMSCs according to the limited clinical evidences available.
Formalismo e incompletud
Authors: Lungarzo Carlos
Published: March 2020

Resumen
What Can We Learn from the Paradoxes? (Part I)
Authors: Mackie J. L.
Published: March 2020

Abstract
Carlos Alchourrón y Eugenio Bulygin, Normative Systems
Authors: Esquivel Javier
Published: March 2020

Resumen
Frege's Problems with "the Concept of Horse"
Authors: Martin Jr. Edwin
Published: March 2020

Abstract
Acerca de las capacidades
Authors: D'Alessio Juan Carlos
Published: March 2020

Resumen
Beliefs about Objects
Authors: Carrier L.S.
Published: March 2020

Abstract
Locuciones e ilocuciones: Searle y Austin
Authors: Rabossi Eduardo A.
Published: March 2020

Resumen
Thinking and the Structure of the World. Discours d’Ontologie
Authors: Castañeda Héctor-Neri
Published: March 2020

Abstract
¿Lo indecible dicho? Una invitación a la muerte
Authors: Margáin Hugo
Published: March 2020

Resumen
Análisis y eliminación: una módica defensa de Quine
Authors: Simpson Thomas M.
Published: March 2020

Resumen
Verdad lógica y significado
Authors: Orayen Raúl
Published: March 2020

Resumen
Consideraciones semánticas sobre lógica deóntica, con especial referencia a la jurisprudencia
Authors: Schmill Ulises
Published: March 2020

Resumen
Rejoinder to Professor Michael Loux
Authors: Castañeda Héctor-Neri
Published: March 2020

Abstract
Jan Lukasiewicz, Para una historia de la Lógica de Enunciados
Authors: Otero Mario H.
Published: March 2020

Resumen
Sobre el concepto de orden jurídico
Authors: Alchourrón Carlos E. , Bulygin Eugenio
Published: March 2020

Resumen
Validez, inferencia e implicaturas I
Authors: Margáin Hugo
Published: March 2020

Resumen
Adolfo Sánchez Vázquez, Del socialismo científico al socialismo utópico
Authors: Tomasini Alejandro
Published: March 2020

Resumen
Jesús Mosterín, Lógica de primer orden
Authors: Cisneros Arturo
Published: March 2020

Resumen
Austin, Strawson and the Correspondence Theory of Language
Authors: Martinich Aloysius P.
Published: March 2020

Abstract
Thomas G. Bever, Jerrold J. Katz y D. Terence Langendoen (eds.), An Integrated Theory of Linguistic Ability
Authors: Vernengo Roberto J.
Published: March 2020

Resumen
Brentano y Quine: modalidades psicológicas de re e indeterminación de la traducción
Authors: Simpson Thomas M.
Published: March 2020

Resumen
Abortion and Moral Safety
Authors: Greenwell James R.
Published: March 2020

Abstract
Verificacionismo y clases naturales en el ataque contra la privacidad
Authors: Villanueva Enrique
Published: March 2020

Resumen
Héctor-Neri Castañeda (ed.), Action, Knowledge and Reality: Studies in Honor of Wilfrid Sellars
Authors: Valdés Margarita M.
Published: March 2020

Resumen
J.C.C. McKinsey, A.C. Sugar y Patrick Suppes, Axiomatic Foundations of Classical Particle Mechanics
Authors: García Aguilar Claudia Lorena
Published: March 2020

Resumen
Acerca de la estructura lógica de la controversia sobre el mal
Authors: Orayen Raúl
Published: March 2020

Resumen
Hobbes and Performatives
Authors: Bertman Martin A.
Published: March 2020

Abstract
Ciencia y filosofía en El azar y la necesidad
Authors: Ponce Margarita M.
Published: March 2020

Resumen
¿Qué hacer en filosofía de la ciencia? Una alternativa en catorce puntos
Authors: Moulines C. Ulises
Published: March 2020

Resumen
Sobre una clase de argumentos antimaterialistas
Authors: Otero Mario H.
Published: March 2020

Resumen
Aristóteles: ΠΕΡІ ΕΡΜΗΝΕΙΑΣ. De Interpretatione
Authors: Osmanczik Ute Schmidt
Published: March 2020

Resumen
H.J. Robinson, Renascent Racionalism
Authors: Beuchot Mauricio
Published: March 2020

Resumen
Karl R. Popper y John C. Eccles, The Self and Its Brain. An Argument for Interactionism
Authors: Villanueva Enrique
Published: March 2020

Resumen
Nietzsche and Anthropomorphism
Authors: Stack George J.
Published: March 2020

Abstract
R.J. Bogdan (ed.), Patrick Suppes
Authors: Quesada J. Daniel
Published: March 2020

Resumen
Kind Words and Understanding
Authors: Platts Mark
Published: March 2020

Abstract
Coherential Validation of Causality
Authors: Alonso-de Florida Francisco
Published: March 2020

Abstract
Hilary Putnam, Mind, Language and Reality
Authors: Villanueva Enrique
Published: March 2020

Resumen
Juicios de valor, positivismo jurídico y relativismo moral
Authors: Esquivel Javier
Published: March 2020

Resumen
Herbert Marcuse y Jürgen Habermas, Teoría y política
Authors: Esquivel Javier
Published: March 2020

Resumen
Predicates, Predicables and Names
Authors: Englebretsen George
Published: March 2020

Resumen
George W. Sefler, Language and the World. A Methodological Synthesis within the Writings of Martin Heidegger and Ludwig Wittgenstein
Authors: Moulines C. Ulises
Published: March 2020

Resumen
Rush Rhees (ed.), Ludwig Wittgenstein. Personal Recollections
Authors: Villanueva Enrique
Published: March 2020

Resumen
Duas tribos e Muitos Círculos
Authors: Dascal Marcelo
Published: March 2020

En este trabajo propongo un marco de referencia, relativamente sencillo y tosco, como punto de partida para la comparación y evaluación de las posiciones, a menudo contrapuestas, tocantes a la relación entre lenguaje y pensamiento.

El marco consiste en una serie de expediciones imaginarias por el escenario de los mundos posibles, en búsqueda de “parlantes” (gente que tiene lenguaje, pero no pensamiento) y de “pensantes” (gente que tiene pensamiento pero no lenguaje). Los cuatro posibles resultados de una primera expedición de este tipo, representan las cuatro perspectivas posibles con respecto a la dependencia conceptual entre el lenguaje y el pensamiento. Todas las perspectivas están ilustradas abundantemente en la literatura del presente y del pasado.

Se muestra que, prestando atención a los argumentos aducidos por los defensores de estas perspectivas, es posible llegar a comprender mejor los grados de centralidad y la estructura lógica de las diferentes características usadas generalmente para “definir” los conceptos de lenguaje y pensamiento.

Algunas expediciones imaginarias ulteriores, más complejas, llevan a refinar el marco original, permitiendo, entonces, la discusión de otras cuestiones relativas a la relación entre lenguaje y pensamiento, v.gr., la cuestión de la “dirección de explicación” que se da entre ellos.

En el transcurso del artículo, se analizan las posiciones de Locke, Cordemoy, Sellars, Davidson, Searle, Vigotski y otros.

[M.D.]
Predication: Old and New
Authors: Englebretsen George
Published: March 2020

Resumen
Desmond Lee (ed.), Wittgenstein’s Lectures, Cambridge 1930-32
Authors: Villanueva Enrique
Published: March 2020

Resumen
¿Qué son las constantes lógicas?
Authors: Frápolli María José
Published: March 2020

El artículo ofrece una caracterización de las constantes lógicas, [CL], analizando el significado de las expresiones que son sus contrapartidas en el lenguaje natural. [CL] recoge los rasgos sintácticos, semánticos y pragmáticos individualmente necesarios y conjuntamente suficientes para que una expresión sea una constante lógica. Se obtendrá la siguiente conclusión: que la lista de las expresiones que habitualmente se consideran constantes lógicas no comparten rasgos relevantes desde el punto de vista del significado que justifiquen su tratamiento como un grupo homogéneo. Sólo algunos usos del condicional, de la negación y de ciertos cuantificadores son constantes lógicas genuinas.
Autorreferencia, autoconciencia y la paradoja de Moore
Authors: Vidal Javier
Published: March 2020

La paradoja de Moore es el tipo de absurdo de, entre otras cosas, la aserción de una oración de la forma “p pero yo no creo que p”. Propongo una explicación de la paradoja en términos del uso del pronombre personal “yo”. Más aún, recurro a un modelo del uso competente al que me referiré como modelo de la autorreferencia autoconsciente. A continuación, muestro que la explicación introducida es independiente de otras explicaciones recientes basadas en la naturaleza consciente de la aserción y de la creencia. Pero, además, concluyo que está justificado pensar que ni la aserción ni la creencia son de naturaleza consciente.
Cómo narrar el desarrollo de la filosofía de la ciencia en el siglo XX. Respuesta a Alejandro Cassini
Authors: Moulines C. Ulises
Published: March 2020

Estudio crítico
Pensamientos de primer orden
Authors: Aguilera Mariela
Published: March 2020

Uno de los argumentos en favor de la dependencia entre lenguaje y conceptos descansa en la premisa de que la posesión de conceptos involucra pensamientos de segundo orden y éstos, a su vez, requieren lenguaje. Este trabajo se centra en una variante de este argumento formulada por José Luis Bermúdez. Sostendré que aun cuando el pensamiento de segundo orden suponga competencia lingüística, no es necesario aceptar esa premisa. Propondré, en cambio, dos condiciones alternativas para la posesión de conceptos, la identificación y la generalidad. Si bien ninguna de ellas conlleva el pensamiento de segundo orden, en forma conjunta reflejan importantes aspectos del pensamiento conceptual.
El triple estándar de la razón pública
Authors: Vaca Moisés , Mayans Itzel
Published: March 2020

Varios autores afines al proyecto del liberalismo político han propuesto diferentes modelos de razón pública para enfrentar la situación de desacuerdo moral permanente en las sociedades liberales. En este trabajo presentamos un modelo que defiende dos argumentos. Primero, argumentamos a favor de una interpretación deflacionista de las razones que son aceptables para los ciudadanos razonables. Segundo, introducimos una nueva terminología que distingue entre lo que llamamos razones dependientes, accesibles y aceptables. Sostenemos que sólo las segundas y las terceras son medios adecuados de discusión dentro de la razón pública, y las terceras son un estándar correcto de justificación de política pública.
Funciones y homología funcional en las ciencias cognitivas
Authors: García Claudia Lorena
Published: March 2020

En este ensayo presento brevemente la propuesta de un concepto de homología funcional, junto con sus criterios empíricos. Argumento que dicho concepto es necesario para la articulación de una ciencia cognitiva evolutiva rigurosa y completa. Luego considero la pregunta sobre cuál de los dos principales conceptos de función que han sido desarrollados por filósofos de la biología —a saber, el análisis sistémico o el seleccionista— es el que encaja de mejor manera con mi concepto de homología funcional, y concluyo que la noción de tipo sistémico (inicialmente propuesta por Robert Cummins) es la más coherente con dicho concepto.
W.D. Hart, The Evolution of Logic
Authors: Gutiérrez Ramírez Cristian Alejandro
Published: March 2020

W.D. Hart, The Evolution of Logic, Cambridge University Press, Nueva York, 2010, 299 pp.
A Defense of the Contrastive Theory of Causation
Authors: Céspedes Esteban
Published: March 2020

An argument proposed by Steglich-Petersen (2012) establishes that while contrastive causation can be applied to general causation and causal explanation, it is a mistake to consider it in cases of singular causation. I attempt to show that there is no mistake. Steglich-Petersen’s argument does not seem to be strong enough and is actually circular. Furthermore, I briefly argue that even if we take his argument to be valid, there is still a response from the side of contrastive causation.
¿Cómo mide el riesgo el observador imparcial?
Authors: Heras Antonio J. , Teira David
Published: March 2020

Exploramos aquí la conexión entre los conceptos de riesgo e igualdad en el argumento del observador imparcial. La concepción de la justicia que elegiría un observador imparcial se justifica por la pureza del procedimiento de elección. Sin embargo, si modelizamos esta decisión utilizando medidas del riesgo habituales en matemática financiera, veremos cómo el criterio de elección del observador bajo el velo de la ignorancia contiene una preferencia implícita por el grado de desigualdad resultante. Esto nos obliga a reconsiderar la pureza procedimental de la elección.
El regreso de Bradley y el problema de la unidad-compleja: ¿Tropos al rescate?
Authors: Briceño Sebastián
Published: March 2020

Suele sostenerse que el regreso de Bradley admite solución dentro de una ontología de tropos. Esto pareciera suceder cuando a un cúmulo se le entiende como constituido por tropos no transferibles. También pareciera suceder cuando uncúmulo es entendido como constituido por tropos transferibles relacionados por un tropo relacional de copresencia cuya existencia dependa específicamente de dichos relata. En este artículo demuestro que estas propuestas no se hacen cargo de la cuestión esencial que subyace al regreso, cayendo en una petición de principio ya anticipada por Bradley.
On Imagination and Convention. Distinguishing Grammar and Inference in Language
Authors: Mena Ricardo
Published: March 2020

Ernie Lepore and Matthew Stone, Imagination and Convention: Distinguishing Grammar and Inference in Language, Oxford University Press, Oxford, 2014, 272 pp.
Epistemología de virtudes robusta: sobre los límites y las posibilidades de su aplicación a la prueba de los hechos en el derecho
Authors: Haddad Bernat Pedro H.
Published: March 2020

El objetivo del presente trabajo es definir los rasgos generales de un modelo de teoría del conocimiento viable para el ámbito probatorio judicial. En concreto, se estudian los límites y las posibilidades de aplicación al derecho de una de las propuestas más relevantes en la epistemología contemporánea: la epistemología de virtudes robusta. Como mostraré aquí, dicho proyecto es inadecuado pues un epistemología de la prueba jurídica satisfactoria y completa exige la conjunción tanto de la perspectiva del agente epistémico (el juez de los hechos) como de la perspectiva del sistema probatorio (las reglas o condiciones de indagación).
Sergio F. Martínez y Xiang Huang, Hacia una filosofía de la ciencia centrada en prácticas
Authors: Guillaumin Godfrey
Published: March 2020

Sergio F. Martínez y Xiang Huang, Hacia una filosofía de la ciencia centrada en prácticas, Instituto de Investigaciones Filosóficas-UNAM/Bonilla Artigas Editores, México, 2015, 216 pp.
Verdad sobre la no existencia: un problema para la teoría reduccionista de tim crane. Nota crítica sobre the objects of thought
Authors: Almagro Holgado Manuel
Published: March 2020

Tim Crane, The Objects of Thought, Oxford University Press, Oxford, 2013, 208 pp.
Análisis del rendimiento académico en un curso de educación superior a través de Open EDX
Authors: Vega López Rodrigo Alejandro
Published: March 2020

Se presenta el análisis de los resultados de un curso electivo implementado en la Universidad de La Serena, Chile. Su objetivo es contribuir a desarrollar futuras líneas de investigación que puedan fortalecer la toma de decisiones en todo lo referente a la articulación del uso de tecnologías en los procesos de enseñanza y aprendizaje. Su alcance es explicativo simple, de carácter temporal-transversal. El universo está compuesto por los estudiantes inscritos en la asignatura y la muestra corresponde a los 72 alumnos que participaron en su ejecución. Para su análisis, se consideran las medidas de posición, de variabilidad y de forma. Además, se determina la frecuencia y el poder predictivo de las estrategias evaluativas sobre el rendimiento académico de los estudiantes. Los resultados indican diferencias entre las frecuencias de ingreso y los perfiles de los estudiantes, además de responder a las estrategias evaluativas propuestas considerando la intencionalidad que posean.
Encuentros entre la Pedagogía crítica y la Teoría de la resistencia
Authors: Villamizar Acevedo Gustavo
Published: March 2020

En un momento de la historia en el que la educación está al servicio del neoliberalismo es necesario replantear su función. Para tal fin se analizan los fundamentos de la Pedagogía crítica y la Teoría de la resistencia y sus puntos de convergencia. Se realiza un recuento por los planteamientos de Habermas, en la Teoría de la acción comunicativa, seguido por los establecidos por Henry Giroux, quien invita a los maestros a analizar el papel de los medios de comunicación como soportes de la ideología dominante y oponerse a ellos a través de una Pedagogía liberadora. Asimismo, el artículo aborda la Teoría de la resistencia, línea de pensamiento que se encuentra con la teoría de Paulo Freire, la cual ve a los docentes como promotores de una educación liberadora. Bajo esta consideración, la Pedagogía crítica es vista como una pedagogía que busca la formación del pensamiento crítico y que considera el aula como un escenario de resistencia.
From Kyzyl to Paris: the geopoetics of the modern psycho logical novel (“Rain in Paris” by R. Senchin)
Authors: Nichiporov Ilya B.
Published: March 2020

The article is devoted to the discussion of modern literary material - R. Senchin’s novel “Rain in Paris” (2018) as a phenomenon of realistic prose. Considered the features of the “novel of a generation”, a variety of geopoetics works, its regional discourses, connecting the distant spatial and sociohistorical plans - from Kyzyl, city of Tuva, to close to the border with Ukraine Bobrov in Voronezh Oblast, Estonia and Paris, the days of being in which involve the central character into the painful process of self-refl ection and reappraisal. Connection of geopoetics with the image of consciousness of the central character and change of historical epochs is traced. In the fi eld of artistic vision of the author of the novel fall tectonic shifts of the 1980s-2010s both in the space of the personal fate of the 40-year-old “hero of time” and his peers, and in the sphere of public life.
Internaliterary synthesis as genre-forming factor in the story of S. Georgievskaya “Love and Cybernetic”
Authors: Chelyukanova Olga N.
Published: March 2020

The article is devoted to the analysis of the stylistic role in intraliterary synthesis which is represented in the story “Love and Cybernetics’’ by S. Georgievskaya. The author of the article shows how as a result of synthesis is organically merged with prosaic content, on the one hand, and content organized according to the principles of lyrical poetry, on the other. The lyration of the prose by S. Georgievskaya is facilitated by the author’s appeal to the possibilities of artistic synthesis. The poetry world of S. Georgievskaya is characterized by a kind of interpenetrability of diff erent genre structures, in a number of which one of the essential places belongs to fairy tale modality. The appeal to the genre canon of the fairy tale reveals the mythopoetic foundations of her lyrical thinking, susceptibility to archetypical images-symbols. The author of the article notes that the story sees the features of a dramatic kind of literature: the emphasis is primarily on action, external and internal-spiritual, and hence - some artifi cial note of what is happening. The author of the article comes to the conclusion that S. Georgievskaya successfully manages to use intraliterary synthesis which is refl ected the plot, composition, the choice of characters, the sequence of motifs and themes.
Kiev as an artistic toponym in “The Song of Igor’s Campaign” and the Chinese translations
Authors: Wang Yu
Published: March 2020

The article explores the toponym “Kiev” as an universal center of the space - time organization of “The Song of Igor’s Campaign”. The capital city of Ancient Russia is mentioned in 10 episodes, in each of which it appears in the symbolic incarnation of a certain political slogan or poetic hyperbole. The study analyzes and compares the image of Kiev, displayed in the original text of “The Song”, its translations into Chinese, and commentaries by Wei Huangnu and Li Xiyin, who discovered the artistic value of the ancient Russian masterpiece to Chinese philologists and a wide circle of readers.
In the cir cle of students and like-minded people: to the 90th anniversary of L.A. Kolobaeva: review of the collective monograph “From Chekhov to Brodsky: Aesthetic and Philosophical Aspects of Russian Literature of the 20th Century”. Moscow: Publishing House of Moscow State University, 2019. 240 p.
Authors: Chelyukanova Olga N. , Kovalenko Alexander G.
Published: March 2020

The review touches upon the problems, which are formulated and solved by the group of authors in the scientifi c study “From Chekhov to Brodsky: Aesthetic and Philosophical Aspects of Russian Literature of the 20th Century”. The importance of scientifi c research, originality, well-based arguments of the authors position, the value and novelty of material are underlined in the review.
“Mayak” (1964-2019) in history and modernity: fragments of the chronicle of the VII Ruzhnikov Readings
Authors: Tikhonova Olga V.
Published: March 2020

The VII Ruzhnikov Readings, the annual scientifi c round table, took place at the Faculty of Journalism at Lomonosov Moscow State University on September 26, 2019. The fi rst time it were initiated in 2013 by the Associate Professor of the Department of Television and Radio Broadcasting O.V. Tikhonova in memory of Professor V.N. Ruzhnikov, a well-known theorist and historian of Russian radio journalism, author of many scientifi c publications. Based on the materials of the Ruzhnikov Readings, many scientifi c publications were published
Functioning of Paired Naming in the Modern Russian language
Authors: Pimenova Marina Vas. , Lianlian Wu
Published: March 2020

The article is devoted to the functioning of paired names in modern Russian language - insufficiently studied stable combinations such as небо и земля, печки-лавочки, хлеб-соль, ни ответа ни привета . These units express a single, undifferentiated meaning, consist of two components connected by a compositional connection that belong to one part of speech (most often in paired names are nouns combinations, although there are also adverbs, verbs, adjectives, pronouns, numerals, interjections, onomatopes, prepositions and particles). Structural-semantic model, which is built on paired naming dates back to the ancient period of the language, however, continues to be used in XX-XXI centuries. The purpose of this article is consideration of features of the semantics and structure of the paired naming by the material from the resource "National corpus of the russian language". In addition, their frequency is presented in newspaper and oral speech, in parallel texts and poetic discourse, as well as in accentological and educational materials.
Smoothness of Generalized Solutions of the Second and Third Boundary-Value Problems for Strongly Elliptic Differential-Difference Equations
Authors: Neverova D. A.
Published: March 2020

In this paper, we investigate qualitative properties of solutions of boundary-value problems for strongly elliptic differential-difference equations. Earlier results establish the existence of generalized solutions of these problems. It was proved that smoothness of such solutions is preserved in some subdomains but can be violated on their boundaries even for infinitely smooth function on the right-hand side. For differential-difference equations on a segment with continuous right-hand sides and boundary conditions of the first, second, or the third kind, earlier we had obtained conditions on the coefficients of difference operators under which there is a classical solution of the problem that coincides with its generalized solution. Also, for the Dirichlet problem for strongly elliptic differential-difference equations, the necessary and sufficient conditions for smoothness of the generalized solution in Holder spaces on the boundaries between subdomains were obtained. The smoothness of solutions inside some subdomains except for ε-neighborhoods of angular points was established earlier as well. However, the problem of smoothness of generalized solutions of the second and the third boundary-value problems for strongly elliptic differential-difference equations remained uninvestigated. In this paper, we use approximation of the differential operator by finite-difference operators in order to increase the smoothness of generalized solutions of the second and the third boundary-value problems for strongly elliptic differential-difference equations in the scale of Sobolev spaces inside subdomains. We prove the corresponding theorem.
Advanced Geriatrics Evaluation Skills
Authors: Brown Mallory McClester , Halpert Karen , Dale Maureen , Helton Margaret , Warshaw Gregg
Published: March 2020

Background and Objectives: Older adults are the fastest growing subset of the population and residency training in the basic concepts of care to the older adult is limited. We created a 1-day interactive training program, Advanced Geriatric Evaluation Skills (AGES), to upskill first-year primary care residents in the care of older adults.
Methods: An interprofessional faculty team developed and taught the IRB-approved course to a convenience sample of family medicine and internal medicine interns in 2017, 2018, and 2019. Topics addressed common geriatric presentations seen in the outpatient setting. The faculty provided useful tips and hints for successful workup, diagnosis, and treatment.
Results: Over the 3 years, 56 of the 135 (41%) first-year primary care residents participated. Residents reported that the course was well organized, relevant, and well taught, and they appreciated the dedicated time to focus on caring for older adults. During 2019, residents completed a pre- and posttest with 25 multiple-choice questions. The average score on the pretest was 76% and the average on the posttest was 88%. Ninety percent of the residents improved their score from the pre- to the posttest.
Conclusions: The development of an AGES program provided a structured geriatric didactic curriculum for primary care residents. The course was well received by the residents, was reported to be relevant and timely, and resulted in increased knowledge in the care of older adults in the outpatient setting.
Residency Setting Association With Resident Substance Use Disorder Training: A CERA Secondary Data Analysis
Authors: St. Louis Joshua , Worringer Emma , Barr Wendy B.
Published: March 2020

Background and Objectives: As the opioid crisis worsens across the United States, the factors that impact physician training in management of substance use disorders become more relevant. A thorough understanding of these factors is necessary for family medicine residency programs to inform their own residency curricula. The objective of our study was to identify factors that correlate with increased residency training in addiction medicine across a broad sample of family medicine residencies.
Methods: We performed secondary analysis of a national family medicine residency program director survey conducted in 2015-2016 (CERA Survey PD-8). We obtained data from the Council of Academic Family Medicine Educational Research Alliance (CERA) Data Clearinghouse. We analyzed residency clinic site designation as a patient-centered medical home (PCMH), federally-qualified health center (FQHC), or both, for their correlation with faculty member possession of DEA-X buprenorphine waiver license, as well as required residency curriculum in addiction medicine.
Results: Residency programs situated in an FQHC were more likely to have faculty members who possessed DEA-X buprenorphine waiver licenses (P=.025). Residency clinics that were both a PCMH as well as an FQHC also correlated strongly (P=.001). Furthermore, residencies with faculty who possessed a DEA-X license were significantly more likely to have a required curriculum in addiction medicine (P=.002).
Conclusions: Our quantitative secondary analysis of CERA survey data of family medicine residency program directors revealed that resident training in addiction medicine is strongly correlated with both residency clinic setting (FQHC or FQHC/PCMH) as well as residency faculty possession of DEA-X licenses.
Integrating Interprofessional Case Scenarios, Allied Embedded Actors, and Teaching Into Formative Observed Structured Clinical Exams
Authors: Cyr Peggy R. , Schirmer Julie M. , Hayes Victoria , Martineau Corinn , Keane Meghan
Published: March 2020

Background and Objectives: Interprofessional education is a critical component of medical student training, yet it is often difficult to implement. Medical students who learn with, from, and about learners from other disciplines have been shown to create more effective and safe health care teams. The investigators wanted to know how participating in two interprofessional observed structured clinical exams (OSCEs) at Tufts University School of Medicine (TUSM) would affect changes in medical students’ attitudes and values in interprofessional teamwork.
Methods: For the academic years 2017 and 2018, two interprofessional case scenarios were integrated into OSCEs for third-year medical students at TUSM, with an allied embedded actor (AEA) playing a social worker to an end-of-life scenario, and an AEA playing the role of a pharmacy student added to a chronic pain scenario. Students participated in didactic training about interprofessional teamwork and received structured feedback regarding interprofessional competencies following simulation cases. Changes in interprofessional knowledge and attitudes were assessed by comparing student pre- and postscenario mean scores on the Interprofessional Socialization and Valuing Scale (ISVS-21, a 21-item scale survey), with students rating themselves on a Likert scale from 1 (not at all) to 7 (to a very great extent). We performed paired t-test analysis on individual pre- and post-ISVS-21 means.
Results: Three hundred fifty-three of the 417 participating medical students fully completed pre- and postsurveys. Students reported significant changes in interprofessional knowledge and attitudes (mean change=1.3, P<.0001). Students and faculty regarded the interprofessional cases very highly.
Conclusions: Placing interprofessional cases involving AEAs into OSCE events is easily replicated, and positively impacts students’ attitudes and values in interprofessional knowledge.
Food Insecurity in Primary Care: Patient Perception and Preferences
Authors: Kopparapu Anil , Sketas Greg , Swindle Taren
Published: March 2020

Background and Objectives: Screening for and addressing food insecurity in primary care may improve associated comorbidities. The purpose of this study was to explore patient attitudes regarding screening for food insecurity and to elicit patient preferences for intervention in a primary care setting.
Methods: Patients (N=284) completed a brief, voluntary survey in a university-based clinic and two community-based clinics over a 5-month period. Respondents were classified as either food-secure or food-insecure based on their responses to a validated food insecurity screener.
Results: Participants stated that screening for food insecurity was valuable in the primary care setting (83.9%). Patients preferred having a nurse ask the screening questions (41.2%). The most popular intervention preference, regardless of food security status or clinic type, was to provide a list of food bank locations (76.4%) and local community organizations (71.6%) and to have referral to financial assistance programs (75.4%). There were no differences in preferences for screening or attitudes toward screening by food security status or clinic type (all P≥.05).
Conclusions: Screening for food insecurity is not yet standard practice, partly due to concerns over potentially alienating patients with the screening questions. Based on our surveyed patient population and their indicated preferences, screening and providing resource referrals for food insecurity is not likely to damage the clinician-patient relationship.
The Synergic Association of hs-CRP and Serum Amyloid P Component in Predicting All-Cause Mortality in Patients With Type 2 Diabetes
Authors: Scarale Maria Giovanna , Copetti Massimiliano , Garofolo Monia , Fontana Andrea , Salvemini Lucia , De Cosmo Salvatore , Lamacchia Olga , Penno Giuseppe , Trischitta Vincenzo , Menzaghi Claudia
Published: March 2020

OBJECTIVE

Type 2 diabetes is characterized by increased death rate. In order to tackle this dramatic event, it becomes essential to discover novel biomarkers capable of identifying high-risk patients to be exposed to more aggressive preventive and treatment strategies. hs-CRP and serum amyloid P component (SAP) are two acute-phase inflammation proteins, which interact physically and share structural and functional features. We investigated their combined role in associating with and improving prediction of mortality in type 2 diabetes.

RESEARCH DESIGN AND METHODS

Four cohorts comprising 2,499 patients with diabetes (643 all-cause deaths) were analyzed. The improvement of mortality prediction was addressed using two well-established prediction models, namely, EstimatioN oF mORtality risk in type 2 diabetiC patiEnts (ENFORCE) and Risk Equations for Complications of Type 2 Diabetes (RECODe).

RESULTS

Both hs-CRP and SAP were independently associated with all-cause mortality (hazard ratios [HRs] [95% CIs]: 1.46 [1.34–1.58] [P < 0.001] and 0.82 [0.76–0.89] [P < 0.001], respectively). Patients with SAP ≤33 mg/L were at increased risk of death versus those with SAP >33 mg/L only if hs-CRP was relatively high (>2 mg/L) (HR 1.96 [95% CI 1.52–2.54] [P < 0.001] and 1.20 [0.91–1.57] [P = 0.20] in hs-CRP >2 and ≤2 mg/L subgroups, respectively; hs-CRP-by-SAP strata interaction P < 0.001). The addition of hs-CRP and SAP significantly (all P < 0.05) improved several discrimination and reclassification measures of both ENFORCE and RECODe all-cause mortality prediction models.

CONCLUSIONS

In type 2 diabetes, hs-CRP and SAP show opposite and synergic associations with all-cause mortality. The use of both markers, possibly in combination with others yet to be unraveled, might improve the ability to predict the risk of death in the real-life setting.
Pengaruh Model Pembelajaran Somatic Auditory Visualization Intellectualy berbantuan Lingkungan Hidup terhadap Hasil Belajar IPA Siswa
Authors: Indrawan Kadek Andre
Published: March 2020

This study aims to determine the significant difference to the results of science learning between fourth graders Elementary School Gugus Ir. Soekarno South Denpasar academic year 2016/2017 which was taught by using SAVI model of assisted living environment and fourth grade students of SD Gugus Ir. Soekarno South Denpasar academic year 2016/2017 which was taught by conventional learning. This type of research is quasi experiment (quasi experiment).. Student learning outcomes data obtained through the test, the test used is the usual double-choice test, after obtaining the data of students' science learning outcomes then analyzed by t-test. Based on the significant level of 5% and dk = 74 (n1 + n2-2 = 37 + 39 - 2 = 74) obtained by ttable of 2.00 while tcount 3.49 (tcount = 3.49> ttable = 2.00). The average grade of the experimental class is 74.05 and the control class is 67.48. Thus, there is a significant difference to the results of science learning between fourth graders Elementary School Gugus Ir. Soekarno South Denpasar academic year 2016/2017 which was taught by SAVI model of environment-assisted learning and fourth grade students of SD Gugus Ir. Soekarno South Denpasar academic year 2016/2017 which was taught by conventional learning.
Formulation of Modified Dense Graded Bituminous Macadam with Low Density and High Density Polythene with Zykotherm Admixture
Authors: Shrivastava Vaibhav , Nema Akhil , Kushwaha Pravin Kumar , Shrivastava Sandeep
Published: March 2020

This study presents the use of waste polythene derived as carry bags from kitchen waste and pond liner polyethelene as LDPE and bottle caps as HDPE as an additive in flexible pavements. In this study we will also add a fix percentage of zykotherm.  Purposes of using above materials are to utilize environmentally unacceptable waste material and to develop a better material mix to resist increased traffic load and temperature effect resulting cracks in the pavement surface. In the proposed study the plastic waste will be cleaned and cut into a size such that it passes through 2-3mm sieve using shredding machine. In this study Dense Bituminous Macadam (DBM) mix will be proposed to prepare by using plain bitumen as a control specimen and bitumen mixed with LDPE 2% and 4% & HDPE 2%, 3%, 4%, 5%) as by weight, with fixed percentage of Zykotherm as 1.5% by weight.Bitumen content is 4.5% by weight for all specimen. The Marshall Stability test, Penetration Test, and softening point test, were conducted on control and modified DBM mixes.