bluuebunny/crossref_metadata_2025 huggingface dataset:
Psychometric properties of the questionnaire on threat perception of chronic illnesses in pediatric patients
Authors: Valero-Moreno Selene , Lacomba-Trejo Laura , Casaña-Granell Sara , Prado-Gascó Vicente Javier , Montoya-Castilla Inmaculada , Pérez-Marín Marian
Published: February 2020

Objective: the objective of the study was to assess the psychometric properties of the Brief Illness Perception Questionnaire in a sample of adolescents with chronic endocrine or pneumological conditions and to analyze the dimensionality and reduce the scale elaborating scales by sex and medical diagnosis. Method: we evaluated 510 patients aged 9-16 years using the Brief Illness Perception Questionnaire and the Hospital Anxiety and Depression Scale. We carried out tests of reliability, construct and criterion validity and a comparison of means based on the diagnosis and socio-demographic variables. The reliability and validity analyses showed adequate psychometric properties for this scale, with better results obtained for a single dimension after eliminating 3 items. Results: adolescents with type 1 diabetes and girls were found to have an increased threat perception of their illness. Anxiety/depression was positively associated with the perception of illness. Conclusion: this questionnaire is a useful and practical tool for evaluating adjustment to illness in pediatric patients.
Work accidents with children and youth in a rural environment in southern Brazil
Authors: Xavier Daiani Modernel , Cezar-Vaz Marta Regina , Bonow Clarice Alves , Schimith Maria Denise
Published: February 2020

Objective: to know the prevalence of occupational accidents in children and youth who work with their families in the rural environment and to identify the associated factors. Method: exploratory, descriptive and analytical study with quantitative approach, developed in three rural areas. Participants were 211 children and young people who assisted the family in rural work. Data collection was performed using a semi-structured questionnaire. Bivariate analysis was performed using Pearson’s chi-square, Fisher’s exact, Student’s t and Mann-Whitney tests and multivariate analysis using Poisson regression. Results: the prevalence of self-reported occupational accidents was 55%. It was highlighted: insect bites (44%), burns (40.5%), falls (27.6%), injury with a working tool (16.4%), electric shock (15.5 %), burn by animal (8.6%), animal bite (6.9%) and pesticide poisoning (2.6%). These were related to shared housing, leisure activity - riding a motorcycle, product resulting from lettuce cultivation and use of personal protective equipment. Conclusion: it is believed that these findings may enhance the development of public policies aimed at preserving the health of these children and young people, regulate working conditions and reduce occupational risks in the rural environment.
Three-dimensional analysis of pile groups subject to torsion
Authors: Zidan Ahmed F , Ramadan Osman M O
Published: January 2020

A series of three-dimensional finite-element models was developed to investigate the non-linear behaviour of pile groups connected to rigid caps and subjected to torsion. Pile groups of sizes 1 × 2, 2 × 2 and 3 × 3 installed in sand were analysed to investigate group resistance as well as the variation of pile flexural and torsion deformation. Furthermore, the relative contributions of the pile cap, pile torsion resistance and pile lateral resistance to group torsion resistance were quantitatively evaluated. The influence of group size, pile spacing, pile length, cap condition and soil stiffness was thoroughly explored. Piles were assumed to behave in a linear elastic fashion, while soil was modelled by way of the non-linear hardening-soil model. The numerical results showed that the contribution of the torsion strength of individual piles to the group overall strength decreases with the increase in group size and pile spacing but increases with the increase in pile length and soil stiffness. Among these parameters, the torsion resisted by individual piles ranged from 20 to 45% of the external applied torque. Moreover, it is found that the pile cap contributes about 7% of group resistance for surface pile caps, while this contribution increases up to 53% for embedded pile caps.
National Wetland Map 5: An improved spatial extent and representation of inland aquatic and estuarine ecosystems in South Africa
Authors: Heidi van Deventer  , Lara van Niekerk  , Janine Adams  , Millicent Ketelo Dinala  , Ridhwannah Gangat  , Stephen J Lamberth  , Mervyn Lötter  , Namhla Mbona  , Fiona MacKay  , Jeanne L Nel  , Carla-Louise Ramjukadh  , Andrew Skowno  , Steven P Weerts
Published: January 2020

The improved representation of freshwater and estuarine ecosystems and associated data was a key component of the 2018 National Biodiversity Assessment, and is an essential step in enhancing defensible land use planning and decision making. This paper reports on the enhancement of the National Wetland Map (NWM) version 5 for South Africa and other data layers associated with the South African Inventory of Inland Aquatic Ecosystems. Detail is provided on (i) the extent of wetlands mapped in NWM5, compared to previous versions of the NWMs; (ii) the improved extent of inland wetlands mapped in focus areas in NWM5 relative to NWM4; (iii) the type of cover associated with the wetlands (inundated, vegetated or arid); (iv) the ecotone between rivers and estuaries; and (v) level of confidence for the inland wetlands in terms of how well the extent and hydrogeomorphic units were captured for each sub-quaternary catchment of South Africa. A total of 4 596 509 ha (3.8% of South Africa) of inland aquatic ecosystems and artificial wetlands have now been mapped, with NWM5 delineating 23% more inland wetlands (2 650 509 ha or 2.2% of SA) compared with NWM4. The estuarine functional zone, which encapsulates all estuarine processes, and associated habitats and biota, was refined for 290 systems totalling 200 739 ha, with the addition of 42 micro-estuaries totalling 340 ha. Nearly 600 000 ha (0.5% of SA) of artificial wetlands were mapped in SA. Inland wetlands are predominantly palustrine (55%), with some arid (34%) and a few inundated systems (11%). Ecotones between rivers and estuaries, ecotones where biota and processes continuously vary from freshwater to estuarine, formed a small fraction (<1.5%) of river total extent (164 018 km). Most inland wetlands (~70%) had a low confidence ranking for designation of extent and typing, because they were not mapped by a wetland specialist and not verified in the field. Future improvements of the map should be focused on catchment-based improvements, particularly in strategic water-source areas, areas of high development pressure and those with low confidence designation.
Investigating the fate of natural organic matter at a drinking water treatment plant in South Africa using optical spectroscopy and chemometric analysis
Authors: Welldone Moyo  , Nhamo Chaukura  , Machawe M Motsa  , Titus AM Msagati  , Bhekie B Mamba  , Sebastiaan GJ Heijman  , Thabo TI Nkambule
Published: January 2020

The removal dynamics of biodegradable dissolved organic carbon (BDOC) and natural organic matter (NOM) polarity fractions at a water treatment plant (WTP) in South Africa was studied using UV-Vis absorbance, fluorescence excitation-emission matrix, and two-dimensional synchronous fluorescence spectroscopy (SFS). This study gave insights into the transformation of NOM due to treatment processes. The objectives of the study were: (i) to use chemometric analysis and two-dimensional SFS correlations to investigate the evolution of NOM arising from treatment processes, and (ii) to access the chemical profile dynamics of polarity and BDOC fractions throughout the treatment train. The UV254 absorbance, which indicates aromaticity, reduced by 45%  along the WTP. Gaussian fitting of UV-Vis data showed a decreasing trend in intensity and number of bands along the treatment process. The removal efficiency of NOM components followed the order: humic-like (HL) > tyrosine-like (TYL) > fulvic-like (FL) > tryptophan-like (TPL) > microbial-like (MBL).  At the source, the relative distribution of the hydrophobic (HPO), hydrophilic (HPI), and transphilic (TPI) fractions was 45%, 31%, and 24%, respectively. The HPI was recalcitrant to treatment, and the TYL component of the HPI fraction was conjectured to be a disinfection byproduct limiting reagent. The HL and FL components of the BDOC fraction were the major substrates for bacterial growth. According to two-dimensional-SFS correlation, TYL, TPL, and MBL varied concurrently across the treatment stages. Used for the first time in South Africa, the robustness of a multi-dimensional approach of optical methods coupled with chemometric tools for the assessment of the fate of NOM along the treatment processes was revealed by this study.
Baseline adjustment methodology in a shared water savings contract under serious drought conditions
Authors: HE Jacobs  , JL Du Plessis  , Nicole Nel  , S Gugushe  , S Levin
Published: January 2020

Baselines are often employed in shared water saving contracts for estimating water savings after some type of intervention by the water service company. An adjustment to the baseline may become necessary under certain conditions. Earlier work has described a number of relatively complex methods for baseline determination and adjustment, but application in regions faced with relatively limited data becomes problematic. If the adjustment were determined before finalising the contractual matters, it would be possible to gather the required data in order to determine the adjustment. However, in cases where no adjustment was fixed prior to the contract, a method is required to determine an adjustment mid-contract based on whatever data are available at the time. This paper presents a methodology for baseline adjustment in an existing shared water savings contract and explains how adjustment could be determined mid-contract, under conditions of limited data. The adjustment compensates for expected reduced water consumption due to external influences induced by serious water restrictions, typically introduced during periods of drought. The fundamental principle underpinning the baseline adjustment methodology presented in this paper involved segregating real water losses from the actual consumption of end-users, preferably by analysing the minimum night flow. In the absence of recorded night flows, an alternative procedure involving the minimum monthly consumption pre- and post-baseline was employed. The baseline adjustment method was subsequently applied in a South African case study, reported on separately. This technique is helpful because adjustments could be determined without adding unnecessary complexity or cost, and provides a means to resolve disputes in cases where unexpected savings occur mid-contract.
The natural adaptive evolution of cancer: The metastatic ability of cancer cells
Authors: Olteanu Gheorghe-Emilian , Mihai Ioana-Maria , Bojin Florina , Gavriliuc Oana , Paunescu Virgil
Published: February 2020

The ability of cancer to adapt renders it one of the most challenging pathologies of all time. It is the most dreaded pathological entity because of its capacity to metastasize to distant sites in the body, and 90% of all cancer-related deaths recorded to date are attributed to metastasis. Currently, three main theories have been proposed to explain the metastatic pathway of cancer: the epithelial–mesenchymal transition (EMT) and mesenchymal–epithelial transition (MET) hypothesis (1), the cancer stem cell hypothesis (2), and the macrophage–cancer cell fusion hybrid hypothesis (3). We propose a new hypothesis, i.e., under the effect of particular biochemical and/or physical stressors, cancer cells can undergo nuclear expulsion with subsequent macrophage engulfment and fusion, with the formation of cancer fusion cells (CFCs). The existence of CFCs, if confirmed, would represent a novel metastatic pathway and a shift in the extant dogma of cancer; consequently, new treatment targets would be available for this adaptive pathology.
Lysozyme in the treatment of non-infectious sore throat
Authors: Glamočlija Una , Mehić Meliha , Šukalo Aziz , Tanović Avdić Amna , Džananović Jaganjac Jasna
Published: January 2020

Sore throat is a common reason for seeking medical help [1]. It can have infectious and non-infectious aetiology [2]. The term “sore throat” is usually associated with an infectious agent (bacteria, viruses, and less commonly fungi) [1,3,4]. The terms “throat discomfort“,“throat irritation“ or “functional dysphonia due to the occupational diseases“ (which represents voice disorder) are often used in the same sense as a non-infectious sore throat [2,3]. It is identified by the exclusion of infectious aetiology symptoms accompanied by persistent sore throat symptoms (tingling and scratching sensation in the throat, hoarseness or muffled voice, foreign body sensation in the throat, coughing, difficulty in swallowing accompanied by pain) [2,5].

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Dot Blot of CCSP protein v1
Authors: N. García Luciana
Published: January 2020

Dot Blot Analysis The CCSP protein expression was evaluated in lung homogenates using a Bio-Rad kit. Samples were then adjusted to 5μg/μl in PBS, pH 7.4, and 10μl of each sample were spotted onto a Hybond C membrane (Amersham Pharmacia). Then, the membrane was blocked with 5% fat-free milk in PBS buffer for 1h, before being incubated for 3h with the rabbit primary antibody anti-CC10 1:500 (Santa Cruz Biotechnology) in blocking buffer at room temperature. After washing with TBS–Tween-20 buffer, the membrane was treated with a HRP-conjugated anti-rabbit antibody (Jackson Immunoresearch) and the next handle was as described above for Western blot
Evaluasi Inverse Kinematics untuk Robot Quadruped Menggunakan Sensor Accelerometer
Authors: Nasrudin Ahmad Iqbal , Anam Khairul , Prawira N M. Agung
Published: January 2020

Quadruped robot is one of the types of robots that move using legs 4 compiled by some of the servo motor as a driving force on each foot ft the DOF is used. However, problems arise when this robot is confronted on the inclined plane, because the burden is borne out every servo motor on the feet will be different, so can make a fast servo motor damaged. This research was conducted on the design of the quadruped robot system for stability on the inclined plane using the accelerometer sensor and the application of the inverse kinematics method with PID control of Ziegler-Nichols. The results of tests obtained response robots in stabilizing the body when faced with the inclined plane with some degree of slope of the pitch and roll. In this research was conducted some test for quadruped robot: static Testing robot against the angel of the pitch in the standby retrieved response average robot in stabilizing the body is 245 ms, static Testing robot against the angle of roll in standby retrieved response average robot in stabilizing the body is 280 ms, dynamic Testing robot against the roll and pitch in standby retrieved response average robot in stabilizing the body is 8 seconds, Static Testing robot to stabilizing the body against the angel of roll in running the largest robot oscillations obtained 10 degrees, dynamic Testing robot to stabilizing the body against the angle of roll in run retrieved response average robot in stabilizing the body is 490 ms.
Problemas de edición, difusión y divulgación de la producción de conocimiento en educación física, deporte y lúdica en Colombia
Authors: Urrego Dr. León
Published: January 2020

El campo de conocimientos que agrupa la educación física, el deporte, la recreación y otros temas afines en Colombia tiene un desarrollo precario en cuanto a los procesos de publicación de conocimientos, y por consiguiente es limitado el escenario de desarrollo disciplinar, científico y cultural de este campo emergente. Este documento describe dicha problemática.
EFECTOS EN LA INTENCIÓN DE COMPRA DE PIRELLI MEDIANTE EL PATROCINIO DEPORTIVO EN EL WORLD SUPERBIKE
Authors: Visa Carol Marta , De Blas Foix Xavier , Abadia i Naudí Sixte
Published: January 2020

Nos últimos anos o patrocínio esportivo converteu-se em uma importante indústria mundial, como parte integrada da estratégia de comunicação dentro do departamento de marketing das corporações. Eventos esportivos como World Superbike concebem-se como muito atraentes em dita estratégia de patrocínio. Esta investigação analisa o efeito na intenção de compra da marca Pirelli a partir de sua estratégia de patrocínio de SBK, mediante a administração de um questionário a 140 assistentes à penúltima prova do circuito de 2015 celebrada em Jerez (Espanha). Os resultados mostram uma intenção de compra de 80% a favor. Encontrou-se uma associação entre a atitude para o evento e o conhecimento das marcas patrocinadoras, bem como entre a atitude para o evento e a atitude em frente à Pirelli. Por outro lado, não se encontraram variáveis reveladoras para a intenção de compra.
Reseña de libro: Administración y gestión de organizaciones deportivas
Authors: Medina Baltazar
Published: January 2020

El libro Administración y gestión de organizaciones deportivas es una contribución al área de la administración deportiva, apoyada por la Editorial de la Universidad de Antioquia en su colección Formación / Deportes, que ofrece orientaciones conceptuales, procedimentales y actitudinales, para la formación de futuros profesionales y el desempeño de líderes actuales en la dirección de organizaciones del deporte, la educación física, la recreación y la actividad física, en temas de legislación, modelos de gestión, proceso administrativo, planificación estratégica de eventos, mercadeo deportivo, gestión de instalaciones y equipamientos deportivos y gestión de redes.
Transmutación texto-ilustración: un modelo para el análisis de su efecto sobre las dinámicas y funciones de los libros infantiles
Authors: Echauri Galván Bruno
Published: January 2020

The present paper aims to apply theoretical aspects of translation studies to the analysis of picture books. For this purpose, it introduces a three-stage analytical model aimed at the study of text-picture transmutations in the aforementioned genre. In the first stage, the information that the visual element (picture) conveys, adds, omits or modifies compared to the verbal element (text) is identified using different translation strategies and procedures. In a second stage, these results are used for the study of text-picture dynamics, which determine the message that both elements' convergence will eventually transmit. In the third one, the information that stems from the previous stages is used to identify some of the main functions of children´s literature and to establish to which extent they are foregrounded or overshadowed by the interrelationship between texts and pictures. As a means to exemplify the application of this analytical model, the paper studies various pas sages and their corresponding illustrations from Marla Frazee's A Couple of Boys Have the Best Week Ever.
La traducción de elementos textuales en obras de arte contemporáneo: tendencias, retos y propuestas
Authors: Huertas Abril Cristina A. , Márquez Garrido Rocío
Published: January 2020

Starting from Genette’s (1987) notion of ‘paratext’, which is the foundation of Yuste’s (2015) theory of ‘paratranslation’, this paper will analyse what happens, as far as the viewer’s experience is concerned, when an art work presents textual elements in a language different from the viewer’s language. To this end, we will identify the verbal elements included in works exhibited in art fairs, paying special attention to the International Contemporary Art Fair of Madrid (arco), and will analyse the adequacy of the translator’s figure in events of this sort. From a selection of works in which text forms part of the visual experience, either because it constitutes a fundamental part of them or because it results in the whole work, we will reflect on the different possible strategies to make them accessible to the viewer, allowing a complete experience of the work.
individuação psíquica para além da individuação humana - a coindividuação com o Mundo
Authors: Sanches Vilalta Lucas Paolo
Published: January 2020

Dando continuidade as investigações desenvolvidas em nossa dissertação de mestrado, pretendemos oferecer uma resposta alternativa ao problema colocado por Michel Serres de como é possível escutar a voz do Mundo este sujeito esquecido e atacado que parece agora se voltar contra nós. Para isto, partiremos da análise de como Gilbert Simondon oferece um conceito de individuação psíquica que excede a mera individuação psicossocial dos seres humanos. A individuação psíquica não se reduz à reflexividade ou à consciência, mas é pensada como uma operação de autoproblematização que faz surgir o sujeito. Analisando esta operação, apontaremos como a gênese do indivíduo psicossocial é correlata a outros processos de individuação do Mundo, e assim, como o sujeito simondoniano surge de uma coindividuação entre a individuação psíquica e as individuações do Mundo.
Gilbert Simondon y Jean Piaget: a propósito del argumento del isomorfismo
Authors: Builes Roldán Isabella
Published: January 2020

En el presente artículo analizamos el argumento del isomorfismo, propuesto principalmente por la teoría de la Gestalt en psicología, a la luz de algunos elementos de la teoría de la individuación del ser de Gilbert Simondon y de la epistemología genética de Jean Piaget. Tenemos en cuenta que la propuesta de Piaget es una de las bases teóricas para la individuación psíquica y transindividual simondoniana, y, con base en esto, se ponen en relación ambos autores, a propósito del argumento del isomorfismo entre los distintos niveles de la realidad: físico, químico, biológico, psicológico y psicosocial o transindividual.
Explorando la construcción de la subjetividad en un hospital universitario: del ejecutor de oficios, al trabajador psicologizado
Authors: Pulido Martínez Hernán Camilo , Mejía de Mesa Marietta
Published: January 2020

El artículo presenta una serie de figuras de la subjetividad laboral que emergieron en un hospital universitario entre los años 1942 y 2014. Se considera el surgimiento de estas figuras a la luz de: las transformaciones de las condiciones laborales, los cambios geopolíticos en los modelos del ejercicio de la medicina, el desarrollo de la psicología, así como de las prescripciones nacionales e internacionales para la regulación del trabajo. Los materiales que se utilizaron provinieron de estudios que consideraban o describían diversos aspectos para el manejo de los trabajadores en el hospital. Los resultados muestran la relación entre las concepciones acerca de cómo los trabajadores son y cómo deben actuar antes y después de la introducción de la psicología académica.
Neurofeedback y trauma craneoencefálico frontal: estudio de caso
Authors: Luna Hernández José Alberto , Hernández Arteaga Isabel , Santander Araujo Richard Alejandro
Published: January 2020

Este artículo presenta los resultados de la investigación sobre el tema de Trauma Craneoencefálico (TCE), una lesión adquirida que genera cambios a nivel cognitivo funcional y emocional. Objetivo: comprobar la efectividad del programa de rehabilitación atencional mediante neurofeedback, en paciente con TCE leve frontal. Metodología: estudio preexperimental con paciente de 29 años, a quien se aplicó evaluación pretratamiento, se intervino con 12 sesiones de neurofeedback y se evaluó postratamiento; estudio empírico-analítico de tipo explicativo. Resultados: indicaron cambios significativos en procesos principalmente atencionales. Conclusiones: se comprobó efectividad del programa, comparando datos pre y post-tratamiento, analizados para medir la magnitud del cambio terapéutico, indicando nivel confiable de efectividad; de igual manera se evidenció alcances importantes del efecto positivo en procesos de memoria y funciones ejecutivas.
Acercamiento al campo de la Psicología aeronáutica
Authors: Galeano Arias Felipe
Published: January 2020

El impacto de la psicología en el sector aeronáutico es innegable. Este artículo presenta un estudio de profundización que indaga la forma en la cual el sector aéreo ha recurrido a la ciencia que indaga por las motivaciones del comportamiento, y trata de que ésta permita entender de qué manera la actuación humana se ajusta con los objetivos que buscan fomentar y mantener la seguridad operacional a través del estudio e intervención sobre el elemento humano y la comprensión de los Factores Humanos en Aviación. Se hace un recorrido por la definición del campo y la forma en que éste, desde sus comienzos, tuvo un interés por las respuestas comportamentales humanas en las condiciones de vuelo, así como preguntas sobre la selección de las personas que intervienen en la operación aérea y finalmente, el impacto de este campo en el contexto colombiano. El presente texto pretende situar cómo se ha definido la psicología aeronáutica, cuál es su objeto de estudio y la concepción de sujeto al interior de esta. Así mismo, plantear algunas de las limitaciones del hacer del psicólogo en este campo.
Invirtiendo el aula en asignaturas de Gestión de Empresas utilizando diferentes herramientas metodológicas
Authors: Jimenez Rocio Martinez , Ruiz Jiménez Carmen
Published: January 2020

En los últimos años hemos vivido un cambio importante en el ámbito universitario, que ha provocado que sean necesarias nuevas metodologías docentes en las que el estudiante adquiera un rol mucho más activo y responsable de su propio aprendizaje. En esta línea nos encontramos con un nuevo modelo de enseñanza-aprendizaje como es el aula invertida o flipped classroom (Bergmann y Sams, 2012). Esta metodología supone que el tiempo de clase en el aula se dedica a aplicar, experimentar, indagar, etc.; esto es, a trabajar los niveles más altos de la taxonomía de Bloom. Para ello, el profesorado debe elaborar diferentes prácticas o actividades que sirvan al estudiante para reforzar lo aprendido previamente en casa y que, siguiendo a Santiago y Bergmann (2018) pueden incluirse dentro de, entre otras, las siguientes categorías: enseñanza entre iguales, aprendizaje basado en proyectos, estudios de casos, simulaciones, role-playing, aprendizaje cooperativo y gamificación.

En este trabajo presentamos la valoración realizada por los estudiantes sobre las diferentes herramientas utilizadas al invertir el aula en dos asignaturas relacionadas con la gestión empresarial. Más concretamente, analizamos el grado de interés y diversión que han suscitado en ellos, así como en qué medida cada una de estas técnicas les ha hecho participar más activamente, ha mejorado la comunicación con los compañeros y con el profesorado y ha contribuido a una mayor comprensión de las asignaturas. Los resultados muestran que las tres metodologías mejor valoradas por los estudiantes son: la gamificación, el role-playing y el aprendizaje basado en proyectos.

En este trabajo presentamos la valoración realizada por los estudiantes sobre las diferentes herramientas utilizadas al invertir el aula en dos asignaturas relacionadas con la gestión empresarial. Más concretamente, analizamos el grado de interés y diversión que han suscitado en ellos, así como en qué medida cada una de estas técnicas les ha hecho participar más activamente, ha mejorado la relación con los compañeros y con la profesora y ha contribuido a una mayor comprensión de la asignatura. Los resultados muestran que las tres metodologías mejor valoradas por los estudiantes son: la gamificación, el role-playing y el aprendizaje basado en proyectos.
Dos experiencias de aplicación del nexo investigación-docencia en Ciencias Sociales: la perspectiva del docente universitario
Authors: Cámara Antonio D. , Barros Rodríguez Francisco , Martínez Carrión José Miguel , Candela Martínez Begoña
Published: January 2020

Hay al menos tres planos desde los que el nexo metodológico investigación-docencia puede contemplarse como factor estratégico en el proceso de aprendizaje universitario: 1) el de la productividad y competitividad científico-académica a nivel institucional; 2) el de la capacitación individual de cara a la integración en mercados laborales crecientemente competitivos y 3) el de la mejora de la eficiencia en el planteamiento de proyectos y gestión de recursos en los sectores público y privado. En los tres planos resulta evidente la contribución potencial de una docencia interactiva y experimental que ceda protagonismo a los estudiantes en la consecución de competencias.

El objetivo de este trabajo es presentar y discutir dos experiencias inspiradas en estas metodologías que se desarrollan en asignaturas de grados de Ciencias Sociales en las Universidades de Jaén y Murcia.

En torno a dichas experiencias se comentan algunos recursos de aprendizaje aplicados en distintas fases del curso y con distintas finalidades: fundamentos de diagnóstico a partir de la resolución de problemas de investigación, asimilación práctica de conceptos, técnicas de generación y de recopilación de información, y elaboración de soportes mediáticos para la presentación y difusión de resultados de investigación. Finalmente se presentan y discuten, desde el punto de vista docente, algunos resultados de aprendizaje obtenidos, las principales dificultades detectadas en la aplicación de la metodología y los avances obtenidos en las competencias establecidas originalmente.

El objetivo de este trabajo es presentar y discutir dos experiencias inspiradas en estas metodologías que se desarrollan en asignaturas de grados de Ciencias Sociales en las Universidades de Jaén y Murcia.

En torno a dichas experiencias se comentan algunos recursos de aprendizaje aplicados en distintas fases del curso y con distintas finalidades: fundamentos de diagnóstico a partir de la resolución de problemas de investigación, asimilación práctica de conceptos, técnicas de generación y de recopilación de información, y elaboración de soportes mediáticos para la presentación y difusión de resultados de investigación. Se comentan asimismo los principales condicionantes a los que se hace frente en el desarrollo de los proyectos. Finalmente se presentan y discuten algunos resultados de aprendizaje obtenidos, las dificultades detectadas en la aplicación de la metodología y los avances obtenidos en las competencias establecidas originalmente.
Internacionalización de los servicios: el caso de los KIS (Knowledge Intensive Services). ¿Son aplicables los modelos tradicionales?
Authors: Martos Martínez Clara Belén
Published: January 2020

La literatura sobre la internacionalización de las empresas, tradicionalmente, se ha aplicado a los bienes puesto que han sido más susceptibles a las transacciones internacionales. Esto se ha debido a que los servicios han tenido unas características muy distintas a la de los bienes que les han impedido, en algunos casos, adoptar ciertas formas de internacionalización. Sin embargo, en las últimas décadas se ha producido algunos cambios en la naturaleza de los servicios que, junto con la aparición de las nuevas tecnologías de la información y de distintas fórmulas de entrada a otros países, entre otros, le han facilitado su expansión en el exterior. En este contexto, el objetivo del trabajo es analizar en qué medida se adaptan algunas de las teorías tradicionales sobre internacionalización a los servicios y cuáles serían los cambios que se habrían de plantear para justificar la adaptabilidad de dichas teorías a los servicios y, especialmente, a los servicios intensivos en conocimiento.
New approaches in drug safety assessment based on information provided by doctors and patients in the register “PROFILE”
Authors: Dmitrieva N. A. , Lukina Yu. V. , Kutishenko N. P. , Martsevich S. Yu.
Published: January 2020

The aim to compare various sources of the pharmacotherapy safety information in the outpatient register.Materials and methods. The original questionnaire included several questions for assessing information about patients’ knowledge of the concept of AEs of drug therapy, awareness of the possibility of drugs’ AEs, how often patients read the instructions for drugs and actions of patients in cases of AEs occurrence. Adverse events appearance were noted by the patients themselves in questionnaire and by doctors when completing the IRCs for the period from September 1. 2017 to May 31. 2018 are compared.Results. Of the 162 patients who answered the questions in the original questionnaire, there were 80 women and 82 men. 112 patients were observed by doctors regularly (at least 1 time per year), 16 people visited doctors 1 time in 1–2 years, 14 people were with a doctor more than 2 years ago, in 18 patients information on the regularity of observation by doctors is not indicated were. According to the questionnaire, the majority of patients (145 (89.5 %)) were familiar with information about the possibility of developing side effects of drugs, and 125 (86.2 %) people received this information from their doctor, 19 (13.1 %) noted that the doctor did not inform them about this. Only 6 patients did not know anything about AE pharmacotherapy. As the questionnaire showed, most patients get acquainted with the instructions for the prescribed medications. Comparison of data from the IRCs and questionnaires revealed more frequent registration of AE by doctors; however, there was an incomplete coincidence of information about the presence of AE from different sources.Conclusion. Using data from the retrospective-prospective registry with obtaining information about adverse events from doctors in combination with simultaneous patients questionare could get more complete information about safety of pharmacotherapy. At the same time solution to the problem of farmacotherapy safety lives in optimizing the doctor–patient relationship.
Contrast-induced nephropathy in patients with acute coronary syndrome with ST-segment elevation: risk factors and prognosis
Authors: Arsenicheva O. V. , Shchapovа N. N.
Published: January 2020

Objective: to study the risk factors for acute renal injury, the dynamics of renal function and prognosis in patients with acute coronary syndrome with ST-segment elevation (STEACS) with contrast-induced nephropathy (CIN) after primary percutaneous coronary intervention (PCI).

Materials and methods. We studied 20 patients with STEACS, who developed СIN after PCI (follow-up group), and 98 patients with STEACS without СIN (comparison group). All patients were measured plasma creatinine level and glomerular filtration rate by the formula CKD-EPI before and 48 hours after PCI. CIN was detected with an increase in creatinine levels in the blood by more than 26.5 µmol / l from the baseline 48 hours after administration of radiopaque drug (RCP). Endpoints were evaluated at the hospital stage and within 12 months after PCI.

Results. CIN after PCI occurred in 16.9 % of patients with STEACS. Among patients with СIN, persons aged over 75 years (60 %), with diabetes mellitus (45 %), chronic kidney disease (75 %), postinfarction cardiosclerosis (50 %), chronic heart failure of functional class III–IV (80 %), developed acute heart failure T. Killip III–IV (90 %) were significantly more often observed. The left ventricular ejection fraction was lower in patients with СIN (p <0.05). The average increase in plasma creatinine 48 hours after PCI was higher in the follow-up group (p <0.05). In patients with СIN more often, than without СIN, three-vascular lesions of the coronary bed were detected (65 and 25.5 % respectively, p <0.001). The same trend was observed, when assessing the average number of coronary artery stenoses, the number of implanted stents and the volume of RCP used. Patients with СIN, than without СIN, were longer in hospital (12.1 ± 0.96 and 10.2 ± 1.11 days respectively, p <0.05) and more often needed re-hospitalization within 12 months after PCI (34 and 4.1 % respectively, p <0.05).

Summary. CIN in patients with STEACS after primary PCI was more likely to develop, if the following symptoms were present: age over 75 years, diabetes mellitus, chronic heart failure, post-infarction cardiosclerosis, chronic kidney disease, low ejection fraction of the left ventricle, initially high creatinine level, development of acute heart failure, trisovascular coronary lesion and multiple coronary stenting. The duration of hospital stay and the frequency of re-hospitalizations within a year after PCI significantly increased in patients in the CIN group.
Clinical case of an acquired hemophilia
Authors: Barlamov P. N. , Vasilyeva E. R. , Golubeva M. E. , Zhelobov V. G. , Shutylev A. A. , Kravtsova T. Yu.
Published: January 2020

The aimof the work is to describe the clinical case of formation, diagnosis and treatment of the acquired form of blood clotting factor VIII deficiency – of acquired hemophilia A.Material and methods. Patient R., 71 years, from April 2018, was found an acute hemorrhagic syndrome in the hematomic type of large hematomas manifested submandibular region, neck, chest, right breast, pubic and inguinal regions on the right, the anterior-medial surface of the left femur, anterior surface of left tibia. Standard laboratory tests, computed tomography of soft tissues of the neck, lungs, abdomen; coagulogram; blood clotting factors; inhibitor of factor VIII were evaluated in dynamics during the patient’s stay in the hospital; platelet aggregation function.Results. Typical gematomny type of bleeding, prolongation of coagulation indicators, the presence of the inhibitor factor VIII (7,0 BAA), the decrease in factor VIII (2 %) allowed diagnosis of acquired hemophilia A. Anti-inhibitory coagulant complex, fresh frozen plasma was successfully used for treatment. The patient is under observation in the regional Hematology center. The hematomas were not renewed.Conclusion. Our clinical observation demonstrates the features of the course, the algorithm of diagnosis and management of patients with of acquired hemophilia A.
Paraneoplastic myelitis in a patient with non-hodgkin lymphoma
Authors: Guseynova M. N. , Zaslavskii L. G. , Skornyakova E. A.
Published: January 2020

Objective: description of a clinical case of the development of longitudinally spread transverse myelitis in a young woman suffering from nonHodgkin’s lymphoma (follicular, 1 degree, IIIA stage, complete remission from February 2017). This is a rare, significant case in clinical practice for both residents and neurologists, and the case is under discussion. It requires certain scientific studies in the search for specific antionkoneural antibodies or a more detailed study of the already known. It is necessary to introduce these studies into laboratory practice in Russia, which would help to accelerate the diagnosis of paraneoplastic myelitis.

Materials and methods. Patient B., 30 years old, has been suffering non-Hodgkin’s lymphoma since February 2016 (follicular, I degree, IIIA stage, complete remission from February 2017), receives infusions of Rituximab with a dose of 600 mg once in 2 months, the subacute developed pronounced lower spastic paraparesis. In November 2018, suddenly, against the background of complete well-being, weakness and numbness of the legs appeared. The patient asked for help at the Center for Multiple Sclerosis on 11.17.2018, then she was hospitalized and examined. Patient B. received a pulse therapy with methylprednisolone 1000 mg intravenously № 5. Discharged with positive dynamics with a diagnosis of Demyelinating CNS disease, unspecified. Acute protracted transverse myelitis (LETM), EDSS = 3.5 points. On December 13, due to the increase in spacity and leg weakness, she was urgently hospitalized in the neurological department of the Clinical Hospital.

Results. After the completion of laboratory and instrumental examination, the condition was regardedby us as paraneoplastic myelitis. Relapse of lymphoma was ruled out. The treatment was carried out: pulse therapy with methylprednisolone, Plasmapheresis and intravenous administration of IgG (Privigen) with a distinct positive dynamics.

Conclusion. This clinical observation allowed us to become more familiar with paraneoplastic syndromes and, in particular, with paraneoplastic myelitis. In the clinical situation previously described, we encountered a number of features: longitudinally extensive transverse myelitis developed without relapse of lymphoma, progressed rapidly, there was no response to treatment (glucocorticosteroids, plasmapheresis, Rituximab). All these signs and MRI data of the cervical and thoracic spine (a symmetric hyper-intensive signal from level CII to level ThXI, mainly involving the central spinal cord T2 MRI mode) testified in favor of the paraneoplastic etiology of longitudinally extensive transverse myelitis.
Editorial
Authors: Siqueira Joao Paulo Zen
Published: January 2020

Nesta última edição de 2019, a Revista Archives of Health Sciences continua comprometida em sua missão de divulgar o conhecimento científico nas áreas relacionadas à saúde. Com temática diversa, esta edição apresenta contribuições nas áreas da Medicina, Nutrição, Fisioterapia, entre outras. Um dos destaques é um artigo de revisão que aborda anticorpos monoclonais no tratamento oncológico. Essa terapêutica promete diminuir os efeitos adversos dos tratamentos atuais e aumentar a sobrevida dos pacientes. Este artigo revisa diversos anticorpos utilizados, assim como suas probabilidades de provocarem reações infusionais e como deve ser feito o atendimento aos pacientes que recebem este tipo de terapia. Outro destaque, também na área oncológica, é um artigo que estudou a influência da localização primária de neoplasias de colo na sobrevida de pacientes. Utilizando uma amostra robusta, os autores analisaram diversas variáveis, como dados sociodemográficos, clínico-patológicos e de sobrevida, e as correlacionaram com a origem, à esquerda ou à direita, das neoplasias de colo. Incluída também nesta edição, uma revisão possui como tema central doenças inflamatórias intestinais e seu diagnóstico por meio de métodos de imuno-histoquímica. Este artigo examina os principais biomarcadores envolvidos nos processos inflamatórios que auxiliam no diagnóstico, tratamento e acompanhamento destas doenças. Estas são somente algumas das contribuições contidas nesta edição, que possui diversos outros materiais relevantes. Vale a pena ressaltar o trabalho de toda a equipe envolvida nesta publicação que, com dedicação e esforço, tornou possível esta edição. Agradecemos também imensamente o trabalho dos revisores, empenhados em nos ajudar a disponibilizar conteúdo relevante e de qualidade.
Desejamos uma ótima leitura a todos.
GERMAN POLICIES WITH RESPECT TO LANDS OF FORMER POLISH-LITHUANIAN COMMNWEALTH IN WORLD WAR I ERA. PRO-LITHUANIAN AND PRO-BELARUSIAN, OR DIRECTED AGAINST POLISH ASPIRATIONS?
Authors: Gierowska-Kałłaur Joanna
Published: January 2020

The Germans did not fight the Great War to liberate anyone. Their goal was to expand Germany's borders. This paper seeks to develop an old thesis of Franz Fischer about the expansionist nature of the German war objectives through the examination of yet unknown primary sources found, for the most part, in archives in Vilnius. As Fischer demonstrated, Bethmann-Hollweg planned to push away Russia as far as possible from the German borders, and to abolish Petrograd’s hold over non-Russian vassal peoples already in September 1914. Berlin intended to establish a Central European economic union operating de facto under German leadership, although with preservation of the external equality of its members. It seems that this plan was maintained through the war. The Bethmann-Hollweg peace terms, transmitted to Wilson in January 1918, stipulated, among other things, that the lands of the former Polish-Lithuanian Commonwealth should be included in the German economic and military sphere of influence.
RUSSIAN ARMY IN 1917: FROM THE IMPERIAL WAR TO THE SOLDIER PEACE
Authors: Nelipovich Sergey
Published: January 2020

This paper analyzes the actions of the Russian army in the final year of the fightings on the Eastern Front of the First World War. This paper demonstrates that the Russian army in 1917 was undergoing violent internal processes, caused by the desire of various political forces to seize and retain power. The army involvement in the political struggle was steadily increasing and by autumn 1917 it had become an influential political force capable to play independently a decisive role in changing society (the Kornilov affair, the October Revolution in big cities and small communities). The paper concludes that the leadership of the Russian army was unable to achieve success at the front, even with a numerical superiority over the enemy's troops and at the cost of huge losses. At the same time, pacifist sentiments and the desire to end the war by any mean spreadamong the Russian soldiers. These moods were one of the most important factors contributing to the success of the October Revolution in November 1917 and the rapid conclusion of the Brest Peace in March 1918.
TRANSLATION STUDENTS’ VISIONS OF THEIR FUTURE PROFESSION VS REQUIREMENTS OF THE JOB MARKET
Authors: Sereda O.
Published: January 2020

This paper presents findings from a qualitative study in which a method of semistructured interview was employed to investigate the learning experience of internship students. The research analyses the main factors that influence the quality of an internship from the students’ perspective. Special attention is paid to the student’s expectations from internship and match between the job requirements and internships. Specific issues faced by the internship students have been identified.
TEXT TYPE SPECIFICS OF GOVERNMENT POLICY STATEMENT IN GERMANY
Authors: Stasiuk O.S.
Published: January 2020

The article investigates text type specifics of government policy statement in Germany. The major types of the government policy statement in Germany that appear in different communicative situations are described. The first type is the government policy statement that is submitted at the beginning of the legislative session. The second type is the government policy statement concerning current political themes. The language means that are used in the government policy statement of each type are revealed.
Some problems in the statistical processing of astronomic data
Authors: Parnovsky S.
Published: January 2020

The problems that could arise with a correct statistical processing of astronomical data and a search for linear statistical dependences are analyzed. It has been shown that the use of standard statistical software can yield incorrect results. The iterative procedure of processing based on multi-year experience is proposed. It covers all stages: creation of sampling, discarding of outliers, search for statistically significant regressors, excluding insignificant regressors, finding out multiparametric dependencies and their analysis, etc. This paper is a methodological one and is it describes some potential traps in the statistical processing of observational data. We forewarn against some actions that may lead to data selection or to incorrect conclusions about the influence of some factors on the quantity being studied. Some examples of problems associated with data selection, correlation between regressors, Malmquist bias and correction are given.