bluuebunny/crossref_metadata_2025 huggingface dataset:
Modern principles of atherogenic dyslipidemia management in special groups of patients
Authors: Bubnova Marina G. , Parnes Lev E.
Published: February 2021

Aim.To provide modern view on atherogenic disorders in the blood lipid spectrum, the principles of lipid-lowering therapy prescription in certain groups of patients, the safety issues of statin therapy in patients with chronic liver diseases.
Materials and methods.The data of 55 scientific sources published in the Russian and foreign press in 19882020 were analyzed.
Results.It is known that atherogenic dyslipidemia is a key factor in pathogenesis of atherosclerotic cardiovascular diseases. Various disorders in blood lipids and lipoproteins are identified. In this regard, there are certain recommendations for the analysis of lipids and lipoproteins in certain situations. The issues of interpreting extreme deviations from normal values of the blood lipid spectrum are discussed. Patient groups with different levels of the cardiovascular risk, which determines prescription of lipid-lowering therapy, are presented. Statins are the first line of lipid-lowering therapy for both the correction of dyslipidemia and the prevention of cardiovascular complications. The article discusses the tactics of prescribing statins in special groups of patients, their safety issues. It considers promising ways for increasing statins tolerability in patients with chronic liver diseases, primarily with non-alcoholic fatty liver disease, by adding of combined hepatoprotector.
Conclusions.Generally, modern tactics of statins prescription are based on dyslipidemia characteristics and the patients cardiovascular risk level. Moreover, statins are clinically effective in special patient groups and have a good tolerability profile.
Medical rehabilitation approaches in patients with implanted pacemaker
Authors: Iskenderov Bakhram G. , Ivanchukova Marina G. , Berenshtejn Natalya V.
Published: February 2021

In the following review article, the principles and approaches of medical rehabilitation in patients with implanted pacemakers are discussed. It was shown that total benefit results from cooperation among medical, physical and psychological components of rehabilitation program and optimisation of the mode and parameters of cardiac pacing. Social adaptation of the patients with implantable pacemakers is of paramount importance and should be directed on avoidance of external electromagnetic fields and their influence on pacemaker functions, which in turn may be life-threatening for patient and the staff as well. The indications to diagnostic and treatment regimens including physiotherapeutic procedures should be clearly defined in order to avoid potential influence of electromagnetic interference on cardiac pacemaker. The well-structured medical rehabilitation programs need to be organised in order to improve quality of life and patients survival with regard to growing tendency of implantation of cardiac pacemakers.
Influence of metabolic and proinflammatory factors on diastolic heart failure formation in females with essential hypertension
Authors: Barsukov Anton V. , Seidova Alla Yu. , Shcherbakova Ksenia A.
Published: February 2021

Relevance.Diastolic chronic heart failure (CHF) is a characteristic complication of essential hypertension (EH).
Materials and methods.62 females with EH were examined. The first group (n=47, mean age 51.56.2 years) persons with EH complicated by diastolic CHF, the second group (n=15, 49.86.7 years) persons with uncomplicated EH. The diagnosis of CHF in females of the first group is confirmed by the data of the test with 6-minute walking, increased blood content of the N-terminal precursor of the brain natriuretic peptide, the presence of left atrial dilatation, hypertrophy and disturbed left ventricle (LV) relaxation. The levels of indices of lipid, carbohydrate, purine metabolism, mediators of systemic inflammation (С-reactive protein), tumor necrosis factor alpha (TNF-a), interleukin-6 (IL-6) were studied and a correlation analysis of the whole set of laboratory data with 6-minute walking test results and an integral index of diastolic LV dysfunction (E/e).
Results. Females with EH complicated initial manifestations of diastolic heart failure, characterized by significantly higher, but the corresponding values of the reference range, the content in blood TNF-a, IL-6 compared with females with uncomplicated EH. In females with hypertension complicated initial manifestations of diastolic heart failure is established significant correlation between blood levels of atherogenic lipids and lipoproteins, glucose, uric acid, CRP, TNF-a, IL-6 on the one hand and indices characterizing reduced tolerance to physical load, diastolic LV dysfunction.
Conclusion.Formation of diastolic heart failure clinical syndrome as well as disturbances of LV relax function in hypertensive females allows participation of metabolic factors and pro-inflammatory pattern.
Heart failure: actual problems of accounting and paying for hospital admissions (agreed position)
Authors: Samorodskaya Irina V. , Larina Vera N. , Perkhov Vladimir I. , Sivtseva Maria G.
Published: February 2021

The increase in life expectancy of the population, the more frequent occurrence of heart failure (HF) among the elderly and the increasing costs of its treatment are a significant economic burden for the health of any country. The reasons for the hospitalization of patients with chronic HF (CHF) can be either a worsening condition of the underlying disease, which was complicated by HF, decompensation of HF, the need for implantation of resynchronizing pacemakers and other devices, or heart transplantation. Different reasons for hospitalization require different resources. CHF should be taken into account (coded) as the main final diagnosis in those cases when it is the main reason for hospitalization and the greatest expenses for providing medical care. To plan the volumes and analyze the results of inpatient care for patients with HF, it is necessary to make appropriate additions to the state statistical monitoring forms and to the instructions of the Federal Compulsory Medical Insurance Fund to classify cases of medical care as a specific clinical and statistical group.
Hypertrophic cardiomyopathy: a modern view of the problem
Authors: Alieva Amina M. , Almazova Ilda I. , Reznik Elena V. , Pinchuk Tatyana V. , Baykova Irina E. , Kislyakov Vladimir A. , Svetlakov Vyacheslav I. , Kovtyukh Irina V. , Korvyakov Sergey A. , Rakhaev Alik M. , Nikitin Igor G.
Published: February 2021

Hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease, with a prevalence of approximately 1 in 500 among the adult cohort. It is a common etiological factor of sudden cardiac death in the young and a common cause of morbidity and mortality in all age groups. HCM is characterized by a complex pathophysiology, which is manifested by a heterogeneous clinical picture. The mechanism of development of this variant of hypertrophy is not fully understood. Currently, only a part of the genetic mutations that correlate with the development of this pathology has been identified. In this regard, the issue of genetic diagnosis of HCM is very relevant, as it will allow us to conduct advanced screening. A very important task is to develop a personalized approach in the conservative and surgical treatment of people suffering from this variant of cardiopathy.
Peripheral blood leukocyte telomere length as a possible prognostic marker for the development of atrial fibrillation
Authors: Nikulina Svetlana Yu. , Shihkova Ksenya Yu. , Shulman Vladimir A. , Chernova Anna A. , Maksimov Vladimir N.
Published: February 2021

Atrial fibrillation is one of the most common heart rhythm disorders. The most prominent risk factor for atrial fibrillation is advanced age. Population ageing contributes to an increase in both the prevalence of this pathology and socio-economic burden of the disease for society in general and the patient in particular. Adequate therapy and prevention of atrial fibrillation requires the search for novel prognostic risk markers for disease development, progression, and patients response to therapy. One of these markers is the length of telomeres structures at the ends of chromosomes that protect them from degradation during cell division. The article provides an overview of world studies, both confirming and disproving the role of leukocyte telomere length in atrial fibrillation development.
Assessment of the effect of nebivolol and сarvedilol on the functional state of patients with diastolic chronic heart failure
Authors: Tregubov Vitalii G. , Khil′kevich Pavel V. , Shubitidze Iosif Z. , Tregubova Anna V.
Published: February 2021

Aim. To determine the effect of combined therapy with nebivolol or carvedilol on the functional state of patients with diastolic chronic heart failure (CHF).

Material and methods. The study involved 68 patients with CHF and preserved left ventricular ejection fraction, who were randomized into two groups for treatment with bisoprolol or carvedilol. As part of the combination therapy was prescribed quinapril, and if indicated atorvastatin, acetylsalicylic acid in the intestinal soluble shell. Initially and after 24 weeks of therapy were carried out: quantitative assessment of regulatory-adaptive status (RAS), echocardioscopy, treadmill test, six-minute walking test, subjective assessment of quality of life, determination of level of N-terminal fragment of the brain natriuretic peptide precursor in blood plasma.

Results. Both schemes of combined therapy comparably improved the morpho-functional parameters of the heart and quality of life. In comparison with carvedilol, nebivolol more pronouncedly increased RAS and tolerance to physical activity.

Conclusion. In patients with diastolic CHF in combination therapy, the use of nebivolol, in comparison with carvedilol, may be preferable due to the positive effect on the functional state.
Práticas letradas das mulheres estudantes do Miguel Velho: saberes diários
Authors: Santos Bahia Zislene , Lima Barbosa Lícia Maria
Published: February 2021

Este artigo refere-se ao recorte de uma dissertação de mestrado, intitulada Mulheres do Miguel Velho: reinventando letramentos em práticas cotidianas, que constituiu-se na tentativa de conhecer as práticas de letramentos no cotidiano de mulheres. A escolha do tema e do objeto de estudo desta pesquisa está intimamente relacionada com a trajetória de vida pessoal e profissional da pesquisadora. A pesquisa é de inspiração etnográfica, a qual, na primeira fase utilizou a abordagem de pesquisa do tipo Estado da Arte, além de autores que tratassem letramentos, numa perspectiva social. As informações foram coletadas a partir da observação participante, entrevistas semiestruturadas, aplicação de questionário e registros fotográficos. Neste, percebemos que as mulheres do Miguel Velho, se envolvem em diversos eventos de letramento fora da escola e usam suas capacidades e conhecimentos de mundo. São mulheres ativas, independentes, guerreiras, que apesar do rótulo de “iletradas”, conduzem as suas vidas com destreza e sabedoria.
A Interculturalidade nas opiniões de professores de uma escola indígena de Roraima
Authors: Ferreira do Nascimento Raimundo Nonato , Teodósio de Quadros Marion
Published: February 2021

Os debates sobre interculturalidade e educação intercultural, tem sido uma constante nos últimos 20 anos aqui no Brasil. Dentro dos debates sobre educação intercultural destaca-se a educação escolar indígena. Neste artigo, nosso intuito é refletir acerca das opiniões que professores indígenas e não indígenas de uma escola indígena, possuem sobre a interculturalidade a educação intercultural. Para tanto, nos utilizamos de um material recolhido durante o trabalho de campo antropológico realizado nos anos 2011 e 2013 em uma comunidade indígena no estado de Roraima. Os resultados apontam que há uma polifonia relacionada a interculturalidade, bem como a ausência de formação específica e de convivência na comunidade por parte professores não indígenas que atuam nessa escola, como fatores importantes para a ausência de uma educação intercultural.  Por outro lado, o professor indígena considera a interculturalidade como ferramenta importante de respeito entre os mundos indígena e o não indígena, e reconhecimento do mundo indígena.
Los “refugiados” waraos de Venezuela en una comunidad indígena de Guyana: la complejidad de la movilidad en las zonas fronterizas
Authors: Allard Olivier
Published: February 2021

Guyana, en el contexto de la crisis migratoria de Venezuela, ha acogido a “refugiados” (como se les conoce localmente) que son en su mayoría amerindios o indígenas waraos. Un estudio de la zona fronteriza entre los dos países muestra que esta “migración” forma parte de un complejo conjunto de movimientos de diversa amplitud espacial y temporal. La mayoría de los waraos que van a Guyana pertenecen en realidad a una comunidad transfronteriza para la que el cruce de la frontera no es excepcional, especialmente porque la población local es en su mayoría indígena. Sin embargo, cabe destacar que la región se ha desarrollado, no a pesar de la frontera, sino por ella o en torno a ella: actúa como un umbral económico que fomenta el comercio y el contrabando, y proporciona una barrera protectora contra la violencia que ahora afecta a Venezuela. Además de estos usos estratégicos, la frontera también representa una frontera entre dos sistemas de identidad y entre Estados con modos de funcionamiento muy diferentes: por lo tanto, es un lugar de malentendidos prácticos, que también ofrece la oportunidad de poner de relieve discrepancias importantes.
HIGHLY FOCUSED ULTRASONIC DEVICE FOR WOMEN SAFETY APPLICATIONS
Authors: Agrawal Raunak , Dugar Rahul , Surana Saurabh
Published: February 2021

Sound is one of the most important medium used for delivering information. With rising crime in today’s society, especially against women, carrying some sort of effective weapon for self-defense purposes has become quite essential. This technology emits sound in a highly controlled, narrow beam, so that audio can be heard only when you are in the field of beam or in a position to hear the reflected sound from a virtual source .Sound wave in the audible range has a characteristic to spread in various directions while moving, but ultrasound is unidirectional. This characteristic of sound finds applications at a lot of different areas. Parametric loudspeakers can be used in the advertisement industry where audio is considered as a key influence but is abstained from use because the sound being multi-directional spreads and bothers even the people not in target.  Usually, in case of a riot, smoke grenades and tear gases are used to control the rioters, which on addition on controlling the target also affect the innocents. This study highlights on using an ultrasonic weapon rather than weapons like hand gun, which can be unsafe and might also initiate legal intrusion.Nowadays MEMS ultrasonic transducers have been put to use which has got very portable design outlet .The study uses the application of ultrasonic beams and sound focusing to build a portable women safety device similar to that of a stun gun.
INDOOR LOCALIZATION SOLUTION FOR GPS
Authors: Chougule Shreyanka B. , Abdulhayan Sayed
Published: February 2021

GPS technology is used for positioning application and it is highly reliable and accurate when used outdoor. Due to multipath propagation, signal attenuation and blockage its performance is limited in indoor and dense urban environment. As a solution, technologies like Apple’s iBeacon, Radio-frequency identification (RFID), Ultrasonic and Wireless Fidelity (Wi-Fi) access points are used to improve performance in Indoor environment. We are having a look at all these technologies which are meant for GPS Indoor performance improvement in this review paper.
PD CONTROLLER BASED UNMANNED SHIP NAVIGATION
Authors: Jain Adinath , Hari Prasad  , Dahal Sujata , Sudi Rajesh
Published: February 2021

For the improvement of the performance of track keeping of unmanned water vehicle numerous ship models, wave disturbances models and distinct control algorithms has been proposed. Researchers are using variants of PID controllers, Adaptive controllers and Predictive controllers for accurate trajectory control. Being simpler in nature still PID controller are popular in control domain. In this paper we have implemented PD based controller for trajectory control of unmanned vehicle considering all standard models of sea disturbances. Analysis of result obtained using PD control proved that path tracking is more accurate than open loop controller in terms of computation time, complexity and fuel consumption.
The Effects of Coir Fibers on Workability and Strength Properties of Concrete
Authors: Solangi Ghulam Shabir Solangi , Sahito Gulmir Khan Sahito , Keerio Manthar Ali Keerio
Published: February 2021

This study aimed toward analyzing length and content of coir fiber on workability and strength of concrete. For this purpose, different fractions of coir fibers of length as 10 mm, 20 mm and 30mm are used with varying proportions as 0.15%, 20%,0.25%,0.3% and 0.35% by the volume of concrete. One mix of control concrete and 15 mixes of concrete with inclusion of cot fibers were prepared. The experiments were conducted to check the workability, compressive and tensile strength of concrete. It was observed from conducted research, that the workability is decreased with increasing the content of coir fibers. On the basis of conducted research, the inclusion of 0.25% of coir fibers of length 20mm is optimum. With inclusion of  0.25% of coir fibers of length 20mm, compressive and tensile strength is improved as compared to control mix.
38 FLOOR APARTMENT DESIGN WITH SPECIAL MOMENT FRAME SYSTEM (SMF), WITH PERFORMANCE BASED DESIGN USING SNI 1726: 2019 AND SNI 1729: 2015
Authors: Ubaidillah Achmad , Bagio Tony Hartono , Tistogondo Julistyana
Published: February 2021

Apartments are an option for vertical housing. Currently, with the rapid development of technology, a person will tend to choose housing that can support their mobility. So it is planned that an apartment building structure is planned using a Special Moment Frame System using Performance Based Design referring to SNI 1729: 2015 and SNI 1726: 2019. Planned with columns HC 582x500x50x65 and HC 508x462x75x75 as well as WF beams 400x300x12x22 and WF 400x200x12x22. The results show that the columns and beams are strong but wasteful.
Assessment of Physical and Mechanical Properties of Polyurethane as Ground Improvement Material for Peat
Authors: Abdurahman Mohamad Niizar , Kasbi Basri Adnan Zainorabidin , Kassim Azman
Published: February 2021

Peat is considered problematic soil due to its large void ratio, high compressibility and low shear strength. Various ground improvement methods have been developed in recent years to improve peat’s strength properties. Polyurethane grouting is one of the ground improvement methods that is gaining recognition as effective and fast way to stabilize soil. Polyurethane is a lightweight material produced by mixing polyol and isocyanate chemicals. Upon mixing, a polyurethane foam is created which expands up to a few times of its original volume. In this study, the strength characteristics of polyurethane with different mix ratios of polyol to isocyanate were evaluated to determine the optimum ratio suitable to be used to stabilize peat. Polyol to isocyanate ratio of 1:1, 1:1.5, 1:1.2, 1:2.5 and 1:3 were tested in this this research.  The propagation, microstructure and density of polyurethane were investigated. Compressive strength of polyurethane determined using Unconfined Compression Strength test. Polyurethane created with higher ratio of isocyanate bears higher density and compressive strength compared to the polyurethane with lesser quantity of isocyanate. The cell structure of the polyurethane also is smaller with thicker cell walls. However, the curing time consumed by the polyurethane with high ratio of isocyanate is 8 times greater than the normal polyurethane. Thus, polyurethane ratio with fast curing time and high compressive strength was chosen as the optimum mix ratio to be used to stabilize peat.
Induction therapy with Erlotinib (E) and Gemcitabine/Platinum (GP) in stage III NSCLC
Authors: Tobias R Overbeck , Stefan HP Wenleder , Bernhard C Danner , Wolfgang Körber , Karin Toepelt , Bernhard Hemmerlein , Christina Perske , Markus Falk , Markus Tiemann , Claudia Tomala , Elke Stitz , Frank Griesinger
Published: February 2021

Background: In 2004 we started a phase II trial in non-small lung cancer (NSCLC), stage III, with erlotinib followed by a combination with a platinum-based doublet in unselected patients to identify molecular subgroups benefitting from an EGFR targeting approach. Patients and methods: Induction with erlotinib (E, 150 mg, d1-42) was followed by three cycles of gemcitabine (G, 1250 mg/m², d1+d8, q3w) and cisplatin (P, 80 mg/m², d1, q3w). Patients with at least stable disease after E were treated with a GP + E combination. Induction was followed by surgery and radiation. The trial was conducted as a prospective, multi-center, open label, exploratory phase II study to determine pathological response rate (pRR), as well as secondary endpoints disease free survival (DFS) and overall survival (OS). Results: Of 38 prescreened patients 16 were included in the main study. Due to slow recruitment the study had to be terminated early. Combination of E and GP was well tolerated, surgery was feasible after induction therapy in 12 of 16 patients, 7/12 (58%) patients had a major pathological response (MPR). Median overall survival for patients with MPR was 57.7 months (confidence interval (CI), 37.4 to 78.0; n = 7) and for patients without MPR 11.9 months (CI, 6.4 to 17.4; n = 5). 2/16 patients had an epidermal growth factor receptor (EGFR) mutation. Conclusion: Before discovery of distinct molecular mechanisms in NSCLC our study was an attempt to identify clinical and pathological subgroups that would benefit from E induction. Two patients with an EGFR mutation were identified. MPR was a predictor of long term disease free and overall survival.
Dance as Music in George Balanchine’s Concerto Barocco
Authors: Leaman Kara Yoo
Published: February 2021

In George Ballanchine’s Concerto Barocco, a neoclassical ballet choreographed in 1941 to J. S. Bach’s Concerto in D Minor for Two Violins (BWV 1043), there is a memorable passage in which ten dancers hop on pointe while creating surprising visual accents against the music and against each other. The off-beat accents reflect the jazzy character of the ballet, and the pattern they articulate artfully relate to a metrically dissonant rhythmic motive in Bach’s score.
GEÇ OSMANLI DÖNEMİNE AİT ÜÇ FARKLI KONUT ÖRNEĞİ; MİMARİSİ VE SÜSLEME ÖZELLİKLERİ
Authors: DEMİRCİ Doğan
Published: February 2021

Hımış yapı tekniği olarak bilinen içerisi kerpiç ya da moloz taş dolgulu ve ağaç taşıyıcı sistemli, zemin katı çoğunlukla taş olan konut mimarisinin Türk evi tipinin

gerçek temsilcisi olduğu belirtilmektedir. Türk evinin gerçek temsilcisi olarak tanımlanan bu gurup içerisindeki Isparta evleri genellikle bir sokağa cephe veren,

yanında veya arka kısmında bahçesi olan, genellikle iki katlı sofalı yapılardır. Isparta’da bu çalışmada incelenen üç evden ikisi Müslüman ve Türk olan ailelere

aittir. Bunlardan Belkıs Erşahin evi ise Rum evi olduğu düşünülen yapıdır. Üç evin de farklı plan yapısı bulunmaktadır ve her birisi için konutlar için öngörülen üç

ayrı dönemde yapılmış olmaları söz konusudur. Bunlardan en eski tarihli olanı, yapımı 19. Yüzyıl başlarına kadar uzanabileceğini düşünülen, bir Türk evinde

olması gereken yaklaşık tüm özellikleri bünyesinde taşıyan Selahattin Taştekin evidir. Diğer Türk evi olan Doğancı Mahallesi’ndeki Şengül Özdoğan-Özgül Ay-

Fatma İzgi evi ise içeriye alınmış giriş kapısı ve iç sofalı olması nedeniyle muhtemelen 20. Yüzyıl başlarında yapılmıştır. Bu üç evden en geç tarihli olabilecek

Şengül Özdoğan-Özgül Ay-Fatma İzgi evi, Isparta’da 20. Yüzyılın ilk çeyreğinden itibaren uygulanmaya başlayan hem iç sofalı zemin kat hem de iç sofalı bir üst

kat uygulamasıyla döneminin temsilcisi durumundadır. Selahattin Taştekin, Belkıs Erşahin, Şengül Özdoğan-Özgül Ay-Fatma İzgi evleri Isparta merkezinde üç

ayrı dönemde yapılmış farklı mimari cephe ve iç düzenlemesine sahip evlerdir. Bugün her birisi yapıldığı dönemin izlerini taşımaktadır.
Sedation Characteristics of Intranasal Alfaxalone in Adult Yucatan Swine
Authors: Hampton Chiara E , Takawira Catherine , Ross Juliet M , Liu Chin-Chi
Published: February 2021

Compared with intravenous and intramuscular methods, intranasal administration of sedatives is a less invasive and nonpainful technique. In this prospective, randomized, crossover study, we evaluated the sedative characteristics of 2 doses (1 and 2 mg/kg) of alfaxalone administered
intranasally to 7 adult Yucatan swine. We compared sedation scores before and after administration of alfaxalone and between groups by using a composite sedation scoring system (range, 0 to 12, with 12 being the highest level of sedation)). Pigs were randomly assigned to receive 2 doses of
intranasal alfaxalone (1 mg/kg [A1]); 2 mg/kg [A2]) as 2 separate events in a crossover design with a 60-d washout period. Categories scored were posture, palpebral droop, uninhibited behavior, drowsiness, and acceptance of anesthetic facemask. Sedation scores were collected before sedation
was administered and then every 3 min for 30 min afterward. Instilled volumes (mean ± 1 SD) were 5.7 ± 0.5 and 11.3 ± 0.8 mL for A1 and A2, respectively. Both alfaxalone doses produced significant increases in sedation scores compared with baseline. Median sedation scores
for A1 (6; range, 4–12) were not different from those for A2 (6; range, 6 to 12). Intranasal administration of alfaxalone as the sole sedative agent increased sedation scores from baseline, achieving peak sedation at 6 to 9 min after instillation of A2. However, sedation scores were
similar between the 2 groups, and neither dose produced sufficient sedation to facilitate handling or the performance of any clinical procedures. Given the concentration of alfaxalone solution currently available, volume is the major limiting factor regarding testing higher doses of this drug
for its use as a sole sedative agent in swine.
PTBS im Alter
Authors: Höltge Jan , Maercker Andreas , Thoma Myriam V.
Published: February 2021

Der spezielle Umgang mit einem erlebten Trauma und dessen psychopathologischen Folgen im Alter machen das Erkennen und Behandeln der posttraumatischen Belastungsstörung (PTBS) bei älteren Menschen zu einer Herausforderung. Dabei spielen auch Sozialisierungsmerkmale der heutigen älteren Generation eine wichtige Rolle. Nicht ohne Grund wird noch heute die PTBS im Alter als »stummes Problem« bezeichnet. Weiterhin sind unterschiedliche Formen der PTBS, namentlich die aktuelle, verzögerte und chronische PTBS, und damit verbundene Ursachen spezifisch im Alter zu beachten. Auch die wachsendeWahrscheinlichkeit einer multiplen Traumatisierung mit zunehmendem Alter ist zu berücksichtigen. Daher wird als Ergänzung zu gängigen, altersunspezifischen Therapieverfahren ein biografisch informierter Ansatz empfohlen. Dieser findet in der Lebensrückblickstherapie explizit Verwendung. Weiterhin zeigen sich auch PTBSStandardinterventionen im Alter als effektiv. Mehr Forschung bezüglich PTBS im Alter und deren Therapie ist notwendig, um höhere Remissionsraten zu erreichen.
Taxonomy and phylogeny of the basidiomycetous hyphomycete genus Hormomyces
Authors: Mack J. , Assabgui R.A. , Seifert K.A.
Published: February 2021

The taxonomy of the genus Hormomyces, typified by Hormomyces aurantiacus, which based on circumstantial evidence was long assumed to be the hyphomycetous asexual morph of Tremella mesenterica (Tremellales, Tremellomycetes) or occasionally Dacrymyces
(Dacrymycetales, Dacrymycetes), is revised. Phylogenies based on the three nuc rDNA markers [internal transcribed spacers (ITS), 28S large ribosomal subunit nrDNA (28S) and 18S small ribosomal subunit nrDNA (18S)], based on cultures from Canada and the United States, suggest
that the genus is synonymous with Tulasnella (Cantharellales, Agaricomycetes) rather than Tremella or Dacrymyces. Morphological studies of 38 fungarium specimens of Hormomyces, including the type specimens of H. callorioides, H. fragiformis,
H. paridiphilus and H. peniophorae and examination of the protologues of H. abieticola, H. aurantiacus and H. pezizoideus suggest that H. callorioides and H. fragiformis are conspecific with H. aurantiacus while the remaining species
are unlikely to be related to Tulasnella. The conidial chains produced by H. aurantiacus are similar to monilioid cells of asexual morphs of Tulasnella species formerly referred to the genus Epulorhiza. The new combination Tulasnella aurantiaca is proposed
and the species is redescribed, illustrated and compared with similar fungi. The ecological niche of T. aurantiaca and its possible relationship to orchid root endophytes is discussed. A key to asexual genera with similar conidium ontogeny to T. aurantiaca is provided.
Phylogenetic delimitation of Apiospora and Arthrinium
Authors: Pintos Á. , Alvarado P.
Published: February 2021

In the present study six species of Arthrinium (including a new taxon, Ar. crenatum) are described and subjected to phylogenetic analysis. The analysis of ITS and 28S rDNA, as well as sequences of tef1 and tub2 exons suggests that Arthrinium s. str.
and Apiospora represent independent lineages within Apiosporaceae. Morphologically, Arthrinium and Apiospora do not seem to have clear diagnostic features, although species of Arthrinium often produce variously shaped conidia (navicular, fusoid, curved, polygonal,
rounded), while most species of Apiospora have rounded (face view) / lenticular (side view) conidia. Ecologically, most sequenced collections of Arthrinium were found on Cyperaceae or Juncaceae in temperate, cold or alpine habitats, while those of Apiospora
were collected mainly on Poaceae (but also many other plant host families) in a wide range of habitats, including tropical and subtropical regions. A lectotype for Sphaeria apiospora (syn.: Ap. montagnei, type species of Apiospora) is selected among the original
collections preserved at the PC fungarium, and the putative identity of this taxon, found on Poaceae in Mediterranean lowland habitats, is discussed. Fifty-five species of Arthrinium are combined to Apiospora, and a key to species of Arthrinium s. str. is provided.
Palladin is differentially expressed in both lymph node and brain metastases in human breast cancer.
Authors: Mamoor Shahan
Published: February 2021

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that palladin, encoded by PALLD, was among the genes whose expression was most quantitatively different in the brain metastases of patients with metastatic breast cancer. PALLD mRNA was present at decreased quantities in brain metastatic tissues as compared to primary tumors of the breast. Importantly, expression of PALLD in primary tumors was significantly correlated with patient overall survival in patients with breast cancer. Modulation of PALLD expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain.
Learning and Upgrading in Global Value Chains: An Analysis of India’s Manufacturing Sector
Authors: Dutta Sourish
Published: February 2021

The topic of my research is “Learning and Upgrading in Global Value Chains: An Analysis of India’s Manufacturing Sector”. To analyse India’s learning and upgrading through position, functions, specialisation & value addition of manufacturing GVCs, it is required to quantify the extent, drivers, and impacts of India’s Manufacturing links in GVCs. I have transformed this overall broad objective into three fundamental questions:1. What is the Extent of India’s Manufacturing Links in GVCs?2. What are the Determinants of India’s Manufacturing Links in GVCs?3. What are the Impacts of India’s Manufacturing Links in GVCs?These three objectives represent my three chapters in my PhD thesis.
On the working of the mindsponge concept and the bayesvl R package
Authors: AISDL
Published: February 2021

The usefulness of the mindsponge notion has been aided by the philosophical reasoning nature inherent in the Bayesian belief updating process.
Suicidal Ideation and Behavior Rethinking: The Mindsponge Approach
Authors: Nguyen Minh-Hoang
Published: February 2021

Within the literature related to suicidal ideation, several theories have been proposed. However, given the complexity and dynamics in the formation of suicidal ideation and behavior, I propose a new approach - Mindsponge mechanism - that considers suicidal ideation and behaviors as a result of an individual’s information processing. The approach is expected to make sense of previous literature’s inconsistencies and help comprehend complex suicide-related phenomena, such as suicide contagion, etc.
RAB28 is a differentially expressed gene in human brain metastatic breast cancer.
Authors: Mamoor Shahan
Published: February 2021

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that ras-related protein Rab 28, encoded by RAB28, was among the genes whose expression was most quantitatively different in the brain metastases of patients with metastatic breast cancer. RAB28 mRNA was present at decreased quantities in brain metastatic tissues as compared to primary tumors of the breast. Importantly, expression of RAB28 in primary tumors was significantly correlated with patient overall survival in patients with breast cancer. Modulation of RAB28 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain.
Bài học cho doanh nhân phải dựng văn hóa doanh nghiệp - Yếu tố quyết định sự trường tồn của doanh nghiệp
Authors: AISDL
Published: February 2021

Trong một doanh nghiệp, đặc biệt là những doanh nghiệp có quy mô lớn, là một tập hợp những con người khác nhau về trình độ chuyên môn, trình độ văn hóa, mức độ nhận thức, quan hệ xã hội, vùng miền địa lý, tư tưởng văn hóa… chính sự khác nhau này tạo ra một môi trường làm việc đa dạng và phức tạp. Bên cạnh đó, với sự cạnh tranh gay gắt của nền kinh tế thị trường và xu hướng toàn cầu hóa, buộc các doanh nghiệp để tồn tại và phát triển phải liên tục tìm tòi những cái mới, sáng tạo và thay đổi cho phù hợp với thực tế.
Transcranial direct current stimulation with functional magnetic resonance imaging: A detailed validation and operational guide
Authors: Crinion Jenny
Published: February 2021

AbstractIntroduction:Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique used to modulate human brain and behavioural function in both research and clinical interventions. The combination of functional magnetic resonance imaging (fMRI) with tDCS enables researchers to directly test causal contributions of stimulated brain regions, answering questions about the physiology and neural mechanisms underlying behaviour. Despite the promise of the technique, advances have been hampered by technical challenges and methodological variability between studies, confounding comparability/replicability. Methods: Here tDCS-fMRI at 3T was developed for a series of experiments investigating language recovery after stroke. To validate the method one healthy volunteer completed an fMRI paradigm with three conditions (i) no-tDCS, (ii) Sham-tDCS, (iii) 2mA Anodal-tDCS. MR data were analysed in SPM12 with region of interest (ROI) analyses of the two electrode and reference sites.Results: Quality assessment indicated no visible signal dropouts or distortions introduced by the tDCS equipment. After modelling scanner drift, motion-related variance, and temporal autocorrelation we found no field inhomogeneity in functional sensitivity metrics across conditions in grey matter and in the three ROIs.Discussion:Key safety factors and risk mitigation strategies that must be taken into consideration when integrating tDCS into an fMRI environment are outlined. To obtain reliable results, we provide practical solutions to technical challenges and complications of the method. It is hoped that sharing these data and SOP will promote methodological replication in future studies, enhancing the quality of tDCS-fMRI application, and improve the reliability of scientific results in this field.Conclusion: The method and data provided here provide a technically safe, reliable tDCS- fMRI procedure to obtain high quality MR data. The detailed framework of the SOP (in extended data) systematically reports the technical and procedural elements of our tDCS-fMRI approach, which we hope can be adopted and prove useful in future studies.
Pengaruh Kompetensi Profesional Guru Terhadap Prestasi Belajar Siswa Di SMA Kristen Mangkutana Luwu Timur
Authors: Yuliani Nirma , Hana Sarce Rien
Published: February 2021

Tujuan dari penulisan skripsi ini untuk mengetahui apa pengaruh kompetensi profesionalguru terhadap prestasi belajar siswa di SMA Kristen Mangkutana Luwu Timur. Metodeyang digunakan dalam penyusunan skripsi ini adalah metode kuantitatif denganmenggunakan teknik pengumpulan data sebagai berikut: Pertama, pengumpulan datamelalui riset perpustakaan, yaitu membaca buku-buku atau tulisan-tulisan yangberhubungan dengan kompetensi profesional guru terhadap prestasi belajar siswa. Kedua,memperoleh data melalui penelitian lapangan, wawancara kepada kepala sekolah dan guruguru SMA Kristen Mangkutana. Membagikan angket kepada siswa untuk mengetahuiseberapa besar pengaruh kompetensi profesionl guru terhadap prestasi belajar siswa.Kesimpulan hasil penelitian menunjukkan bahwa: Pertama, kompetensi yang telahditetapkan merupakan sebuah keharusan yang harus dimiliki oleh seorang pendidik untukmenolong tercapainya tujuan belajar. Seorang guru harus memperlengkapi diri sebelumterjun ke lapangan agar proses belajar mengajar berjalan sesuai dengan tujuanpembelajaran. Namun dari hasil penelitian penulis dapat dilihat bahwa guru yang tidakmemiliki pendidikan khusus juga dapat berpengaruh positif bagi siswanya karena adanyakemauan untuk belajar. Kedua, guru harus memiliki dan menguasai kompetensi pedagogikkarena seorang pendidik dituntut untuk dapat mengelola pembelajaran dan dapatmengetahui apa yang menjadi kekurangan siswa dalam proses belajar. Ketiga, kompetensikepribadian harus dimiliki oleh seorang pendidik karena peserta didik akan menjadikanpendidik teladan untuk dapat mengubah perilakunya. Keempat, kompetensi profesionalmerupakan pokok dari penulisan skripsi ini. Kompetensi profesional haruslah dimiliki olehpendidik untuk menolongnya mencapai tujuan pembelajaran.
The semiconducting principle of monetary and environmental values exchange
Authors: AISDL
Published: February 2021

This short article represents the first attempt to define a new core cultural value that will enable engaging the business sector in humankind’s mission to heal nature. First, I start with defining the problem of the current business culture and the extant thinking on how to solve environmental problems, which I called “the eco-deficit culture.” Then, I present a solution to this problem by formulating the “semiconducting principle” of monetary and environmental values exchange, which I believe can generate “an eco-surplus business culture.” This work adds one new element, the eleventh cultural value, to the ten core values of progressive cultures postulated by Harrison (2000).
Người giàu không làm việc vì tiền
Authors: AISDL
Published: February 2021

Xin mượn một câu nói nổi tiếng của người cha giàu trong cuốn sách Rich Dad, Poor Dad của tác giả Robert T. Kiyosaki để làm tựa đề cho bài viết của mình.Nhưng thật sự thì mình đang muốn nói về một cuốn sách khác, mà mình đang đọc trong thời gian gần đây: "Văn minh làm giàu và nguồn gốc của cải".
Neural representations of kinship
Authors: Clemens Ann M , Brecht Michael
Published: February 2021

While the fundamental relevance of kinship behavior for evolutionary and behavioral biology has long been recognized, the examination of kinship behavior from a neuroscience perspective is still in its infancy. Kinship is highly conserved from single-celled organisms to humans, where kin preferences are prevalent in behavior and vocal communication. Kin recognition mechanisms are varied, with evidence for both genetic and both prenatal as well as postnatal learning-based kin recognition. Learned kinship mechanisms are predominant in vertebrates and allow for flexibility regarding the concept of kin. We review new evidence for the lateral septum and its role in kinship behavior. We further discuss the discovery of nepotopy, a topographical representation of kin- and nonkin-responsive neurons in the lateral septum. Neural representations of self/other, familiar/unfamiliar, and nepotopy (kin/nonkin) may support a circuit-level framework for a social template through which the mammalian brain learns, categorizes, and selects behavior based on perceived identity.
Cội nguồn của văn minh kinh doanh trong tâm thức người Việt
Authors: AISDL
Published: February 2021

"Văn minh làm giàu và nguồn gốc của cải" của tiến sĩ Vương Quân Hoàng là một trong số ít những cuốn sách viết về kinh tế ở Việt Nam đã đụng đến gốc rễ của một vấn đề mà đôi khi chúng ta đã lãng quên, đó là nguồn gốc của cải, của những xã hội, những nền văn hóa tự thân vận động hoặc trao đổi, giao lưu với nhau bằng kinh tế.
Pengaruh Pelayanan Tutor Terhadap Ketaatan Anak Usia 9-11 Tahun Kepada Orang Tua Di PPA ID-0539 Elshadai Muara Jawaq Kutai Barat
Authors: Agusti Rita , Supartini Tri
Published: February 2021

Adapun yang menjadi tujuan dalam penulisan karya ilmiah ini adalah, untuk mengetahuisejauh mana pengaruh pelayanan tutor terhadap ketaatan anak usia 9-11 tahun kepadaorang tua di PPA ID-0539 Elshadai Muara Jawaq Kutai Barat. Metode penelitian yangdigunakan dalam penulisan skripsi ini adalah dengan menggunakan metode kuantitatif.Untuk melakukan metode penelitian tersebut hal yang akan dilakukan, yaitu: Pertama,pengambilan dan pengumpulan data melalui buku, jurnal, dan skripsi online yang berkaitandengan judul yang dibahas dalam skripsi ini. Kedua, observasi lapangan dan menyebarkanangket tertutup kepada anak PPA yang berusia 9-11 tahun sebagai responden. Ketiga,wawancara langsung kepada beberapa anak usia 9-11 tahun, tutor anak usia 9-11 tahun danorang tua anak usia 9-11. Kesimpulan dari pembahasan karya ilmiah ini, ialah: Pertama,ketika peran tutor pengajar sebagai sumber, fasilitator, motivator, pembimbing danevaluator dilaksankan dengan baik, maka hal tersebut memberikan dampak positif terhadapanak yang tidak hanya dilihat melalui pengetahuan tetapi juga di dalam sikap anak. Kedua,Ketaatan adalah sikap yang harus dimiliki seorang anak. Untuk membantu anak menjaditaat sangat diharapkan orang tua ataupun lingkungan sekitar anak mendukung anak didalam membimbing dan mengarahkan anak terkhususnya tutor di dalam PPA. Ketiga, Daripelayanan tutor melalui setap peran yang telah dilaksanakan dengan sangat baik di dalammembimbing anak memberikan dampak dan pengaruh yang sangat besar terhadap sikapketaatan anak kepada orang tua.
ACSL4 is a differentially expressed gene in human brain metastatic breast cancer.
Authors: Mamoor Shahan
Published: February 2021

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that acyl-CoA synthetase long-chain family member 4, encoded by ACSL4, was among the genes whose expression was most quantitatively different in the brain metastases of patients with metastatic breast cancer. ACSL4 mRNA was present at decreased quantities in brain metastatic tissues as compared to primary tumors of the breast. Importantly, expression of ACSL4 in primary tumors was significantly correlated with patient post-progression survival in patients with breast cancer. Modulation of ACSL4 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain.
Văn hóa doanh nghiệp tại Việt Nam: Chông chênh giữa cái mới và cái cũ
Authors: AISDL
Published: February 2021

Có thể nói, văn hóa doanh nghiệp (VHDN) là phần "hồn" của doanh nghiệp. Những năm gần đây, Cùng với sự phát triển của nền kinh tế thị trường định hướng xã hội chủ nghĩa và sự chuyển đổi cơ chế kinh doanh tại Việt Nam, bất kỳ một doanh nghiệp nào nếu thiếu đi yếu tố văn hóa, tri thức thì đều khó đứng vững được.
NÂNG CAO CHẤT LƯỢNG NGUỒN NHÂN LỰC TẠI BẢO HIỂM XÃ HỘI QUẬN THANH XUÂN, THÀNH PHỐ HÀ NỘI
Authors: AISDL
Published: February 2021

Từ nhận thức trên, thực hiện phương châm “phát triển bền vững, hội nhập và phát triển” phát huy nguồn lực con người là yếu tố cơ bản cho sự phát triển nhanh và bền vững. Nguồn nhân lực có vai trò quyết định đến sự tồn tại và phát triển của Tổ chức. Chính vì vậy, vấn đề đặt ra là làm thế nào nâng cao chất lượng nguồn nhân lực để đáp ứng yêu cầu phát triển của tổ chức và nền kinh tế.
Applying the Evidence We Have: Support for Having Race Conversations in White U.S. Families
Authors: Perry Sylvia , Skinner-Dorkenoo Allison Louise , Abaied Jamie L , Waters Sara
Published: February 2021

Popular press articles have advocated for parent-child conversations about race to prevent children from developing racial biases, yet empirical investigations of the impact of racial socialization in White U.S. families are scarce. Scott et al. (2020) caution against advising parents to engage in such conversations with their children until this topic has received sufficient empirical examination. In this comment, we draw upon the literature on (1) racial socialization, (2) parenting and parent-child discourse, and (3) the role of nonverbal communication in parental socialization to inform our understanding of parents’ ability to engage in race-related conversations in the absence of empirical guidance. We also highlight emerging evidence of the potential benefits of these conversations (even if parents are uncomfortable). In sum, the wealth of existing literature suggests that parents can successfully navigate challenging conversations with their children—which tends to result in better outcomes for children than avoiding those conversations. Thus, although we support Scott et al.’s call for researchers to develop more empirical research, we part with the authors’ assertion that researchers need to wait for more sufficient evidence before providing recommendations to White parents—we believe that the time for White families to begin talking about race is now.