bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantitative Analysis of Serum Levels of Trace Elements in Sudanese Snuff Dippers
Authors: Alsanousi Abdel Azim , Ahmed Abdel Raouf , Modawe GadAllah
Published: October 2019

Background: Oral cancer in Sudan has high incidence rate due to the use of Toombak , a home- made smokeless tobacco, rich in tobacco specific nitrosamines .There have been calls for continuous monitoring on toombak users to discover very early the carcinogenic changes to avoid mortality, and  morbidity.
Objective: The purpose of this study was to assess technically, and financially affordable  methodologies, that are  reliable, reproducible,  sensitive, specific and cost effective valid  for use  in  mass  screening  amongst  the  high  risk  groups. (The toombak  users).The present study was done to evaluate the levels of copper, zinc and magnesium in serum of toombak dippers.  
Materials and Methods: The levels of copper, zinc, and magnesium were estimated in the serum of 150 toombak dippers . The values were compared with 50 normal age matched, healthy control subjects and 50 patients with oral squamous cell carcinoma, using Atomic absorption spectrophotometry.
 Results: There was significant difference of the mean serum copper, zinc, and magnesium levels of toombak  dippers when compared to the normal controls. In oral cancer patients there was significant difference in the copper, zinc, and magnesium levels. Copper level was found increased gradually starting from control through toombak dippers to oral squamous cell carcinoma patients , while the level of zinc and magnesium was found decreased in the same sequence.
Conclusion: Serum may be used as a potential diagnostic tool, which can be efficiently employed  to evaluate the copper, zinc and magnesium  levels in Sudanese snuff dippers for population based  mass screening .Serum trace elements levels could be used as potential  diagnostic markers for early changes caused by toombak dipping.
Keywords: Atomic absorption spectrophotometry, copper,  magnesiumm , zinc,  oral squamous cell carcinoma, tobacco specific nitrosamines,  serum , toombak.
Assessment of the necessity of routine lumber puncture among children with fever and convulsions
Authors: Osman Nader Mutwakel , Gai James Peter Garkuoth
Published: October 2019

The routine investigation of doing lumbar puncture in patient with febrile convulsion is increasing practiced in many hospital.
Objectives:
The aim of this study was to assess the necessity of routine lumbar puncture (LP) to diagnose meningitis in children who present with fever and convulsions.
 Methods:
This is an observational, cross-sectional, hospital-based study, carried out in Mohammed AL-Amin Hamid pediatrics hospital-Omdurman Sudan, during the period from the first of January through 31 July 2018. It involved all (146) children aged 5 months to 6years , who presented with fever and convulsions, undergone lumbar puncture, and  parents signed  written informed consents. Children with known neurological diseases were excluded from this study. Data collected included, age, gender, convulsions type and duration, post-ictal state, routine vaccination status, general condition, recent antibiotics use, past history of fever and convulsions, temperature degree, signs of meningeal irritation, and conscious level. Data were analyzed by Statistical Package for Social Sciences (SPSS) version 23.
Results:
The result revealed that total number of 146 children, male were 62% (n=91), female were 38% (n=55).  5-11 months  35.6% (n=52)  1-3years 43.8% (n=64), and 4-6 years 20.6% (n=30). About 80% of the patients were younger than 4 years of age.  Convulsion was generalized in 97.9%, lasted less than  15 minutes in 99.3%, spontaneously aborted in 94.5%, post-ictal state was brief in 88.4%, first attack in 98.6%, and there was no family history in 97.3%,p=0.000. There was no neck stiffness and photophobia in 92.5% and 98.6% respectively, p=0.000. Patients general condition were well in 76.7% and toxic in 23.3%. Cerebrospinal fluids (CSF) color was clear in 97% and turbid in 3% of patients. CSF white cells was less than  5 in 93.8%, and CSF sugar and protein were normal in 97.3% and 96.6 % respectively, p=0.000. CSF culture was negative for all patients, and almost all (97%, n=141) of the patients were diagnosed as febrile convulsions and sent home, compared to 3% (n=5) who were diagnosed clinically as meningitis.
Conclusion:
This study revealed that, CSF culture was negative for all patients, and almost all were diagnosed as febrile convulsions. However, 5 patients were diagnosed clinically as meningitis. Hence, this findings, challenge the routine lumbar puncture in children who present with fever and convulsion.
THE RELATIONSHIP OF FINANCIAL FACTORS IN ASSET PRICING: THE CASE OF INDONESIAN MARKET
Authors: Aryani Sinta , Kaderi Wiryono Sudarso , P. Koesrindartoto Deddy
Published: October 2019

Purpose of the study: The study shows how the financial factor of Leverage affects the empirical model of asset pricing together with other financial factors, i.e. Size, Book to Market, Operating Profit, and Investment. The contribution of Leverage in asset pricing will be tested, and its effect will be shown in the excess return of the asset.

Methodology: The methodology used in this paper is based on the Fama and French model of asset pricing with additional factors added in the model. Data processing follows the Fama-Mc Beth procedure. Data comes from the Indonesian Stock Market, which consists of more than 500 stocks for ten years period of observation.

Main Findings: The financial factor of Leverage affects the empirical model of asset pricing together with, i.e. Size, Book to Market, Operating Profit, and Investment. All the financial factors in the model are stationary around their mean, or they are non-stationary due to unit-roots. All the independents' variables have P-Value less than 10%.

Implications: This study will be useful for financial investors in building an effective portfolio stock investment. By applying this model to their portfolio investment, the investors could effectively manage their portfolio return. On the management side, managing their financing structure, e.g. Leverage is the objective of the firm to maximize returns of the firms.

Novelty/Originality of this study: The empirical research with the involvement of the financial factor of Leverage has not been performed in Indonesia. The Leverage as the single factor of asset pricing has been considered as a significant financial factor for asset pricing, however, how the Leverage contributes to asset pricing compares to other financial factors has not examined yet.
ANTI-CORRUPTION THE CRIMINAL PROCEDURE LEGISLATION OF RUSSIA
Authors: Yurevich Epihin Alexander , Aleksandrovich Zaitsev Oleg , Pavlovna Grishina Ekaterina , Viktorovich Mishin Andrey , Isaevna Aliyeva Gulnar
Published: October 2019

Purpose: In article current trends of application of the criminal procedure legislation of the Russian Federation in compliance with the purpose of criminal legal proceedings and in the context of counteraction corruption and prevention of abuse of the law of the officials who are carrying out criminal prosecution and judicial review and permission of criminal cases are stated.

Methodology: In the course of the research of problematic issues and statements of the material of the article the dialectic, comparative and legal, law modeling, logical, inductive and deductive methods were used.

Result: As shows investigative and judicial practicians there are enough the facts of unreasonable initiation of legal proceedings concerning businessmen, with an application of measures of criminal procedure coercion (arrest on the property, blocking of bank accounts and so forth) which result is crash of firm. Change of territorial jurisdiction of consideration of the case of another region by the court is directed to the elimination of a possibility of rendering an impact on objectivity of adjudication. Casual distribution of participation of the lawyer in a criminal case to a destination (when he has to be present surely for protection of the defendant) promotes impartiality of realization of the function of protection in pre-judicial production. The intention of the legislator to enter the obligatory video protocol of court session is directed to a performance by all participants of the process of legal instructions and duties will eliminate possible manifestations of corruption character by officials.

Applications: This research can be used for universities, teachers, and students.

Novelty/Originality: In this research, the model of Anti-Corruption The Criminal Procedure Legislation of Russia is presented in a comprehensive and complete manner.
CONFESSIONAL GROUPS IN THE REPUBLIC OF TATARSTAN: IDENTITY AND FEATURES OF ITS DESIGN
Authors: Alekseevna Titova Tatyana , Valeryevna Frolova Elena , Gennadievna Gushchina Elena , Alina Andreevna Kadyrova
Published: October 2019

Purpose: The relevance of the problem is caused by the need for a comprehensive study of interfaith group attitudes in multiethnic and polyconfessional regions of the Russian Federation. The purpose of this article is to analyze the strategies of constructing identity in the environment of religious groups in the Republic of Tatarstan in 2017 - 2018.

Methodology: The Leading approach to the study of this problem is a multi-paradigm methodology. The article gives a comparative description of the world outlook of the three studied groups -Muslims, Orthodox, and Atheists. Special attention is paid to the analysis of mechanisms of religious socialization and transmission of religious values.

Result: It is concluded that Muslims attach more importance to the implementation of religious rites and practices; the family is considered the main agent of religious socialization, they are more characterized by the position of "religion is not chosen." The materials of the article can be useful for ethnologists, social and cultural anthropologists, political scientists, as well as representatives of bodies and structures in charge of interethnic and interreligious interaction.

Applications: This research can be used for universities, teachers, and students.

Novelty/Originality: In this research, the model of Confessional groups in the Republic of Tatarstan: identity and features of its design are presented in a comprehensive and complete manner.
THE SOCIAL AND ETHICAL VALUES IN THE SELECT NOVELS OF SUDHA MURTHY
Authors: Saleh Alyahya Rimah
Published: October 2019

Purpose/Objective of the Study: Sudha Murthy through her novels empowers women and motivates them to be courageous in adverse situations. The main purpose of this piece of research is to study the struggle faced by the women protagonists in the Select novels of Sudha Murthy titled ‘Gently Falls the Bakula’ ‘House of Cards’ and ‘Mahaswetha’ and how they rise above their mundane existence in search of a meaningful life and start a new life to fulfill their aspirations.

Methodology:  To achieve the purpose of the study, a systematic review of research literature was undertaken. Three novels namely ‘Gently Falls the Bakula’ ‘House Of Cards and ‘Mahaswetha’ have been critically analyzed. In addition to this, the research articles published in the Peer-Reviewed Journals were also examined. With the help of the literature, we were able to study the struggle of women and how they overcome the barriers by finding a solution to lead a meaningful life.

Main Findings: The findings that emerged from the Study reveal the violence, denigration, and exploitation faced by the female characters of the novels such as Anupama, Mridula and Shrimati. It is also found that Man-Woman relationship, social acceptance, and estrangement in modern life, forms the core in all the novels namely ‘Gently Falls the Bakula’ ‘House of Cards’ and ‘Mahaswetha’. It is inferred that the women in the novels such as Mridula, Srimati and Anupama are simple, hardworking and innocent throughout, whereas the males - Sanjay, Srikant, and Anand are strongly influenced by the power of luxury, comfort, and materialism, steadily climbing up the corporate ladder without realizing the value of family life. The man’s greed for power, luxury, and social status has proved to be very expensive to the female characters. The female protagonists realize the fact that artificial values and material success cannot make a person successful. They also work tirelessly to overcome the barriers drawn by male-dominated society to lead a purposeful life.

Implications:  Social and Ethical values are delineated in the novels taken for study. Life is depicted as a journey with learning and unlearning experiences meeting with innumerable obstacles and barriers to testing the grit and willpower. These obstacles help us to make a decision as seen in the protagonists depicted by Sudha Murthy. Their choices were hard yet, they gathered courage, purpose, and meaning to create a new horizon.  Getting to know our real worth is a relentless task, it helps us to toughen our values and passion. Self-discovery is not an easy ride and it requires pain and understanding. The characters here gather courage and face a new dawn.
HISTORICAL SIGNIFICANCE OF THE IMAGE OF THE KAZAN VIRGIN IN THE EDUCATION OF SPIRITUALITY, MORALITY, AND PATRIOTISM
Authors: Ravilovich Khairutdinov Ramil , Vladimirovich Morozov Alexander , Gabdulbarovna Mukhametzyanova Flera , Alexandrovna Venidiktova Elena , Sergeevich Chugunov Alexander
Published: October 2019

Purpose: The article presents an analysis of the historical values and roles of the Kazan Virgin in the formation and development of the Russian state, the spiritual, moral and patriotic education of citizens and, above all, the younger generation of the country through the prism of the modern socio-cultural situation.

Methodology: The study implemented the principle of consistency, the principle of objectivity, the principle of the subject-subject approach.

Result: The Kazan Icon of Holy Virgin, the significance of which cannot be overestimated, is a very strong image that has protected the Russian land from foreign invaders from time immemorial. Not only ordinary people prayed to her, but also princes, kings. Particular emphasis is placed on the consideration of the educational component in the modern system of national education, the formation and development of appropriate values and orientations of students, systems of spiritual and moral values, civic identity, the place of spirituality and spiritual culture in the personality structure. The authors substantiate the importance of the image of the Kazan Virgin in solving the problem of spiritual, moral and patriotic education of the population.

Applications: This research can be used for universities, teachers, and students.

Novelty/Originality: In this research, the model of Historical Significance of the Image of the Kazan Virgin in the Education of Spirituality, Morality, and Patriotism is presented in a comprehensive and complete manner.
LAICISM IN THE REPUBLIC OF TURKEY IN THE 1920-1930S
Authors: Izmaylov Rustam , Imamutdinova Albina , Mefodeva Marina
Published: October 2019

Purpose: The article deals with the Kemalists' policy of secularization and the inclusion of the laicism principle in the ideological doctrine of the Turkish Republic in the 1920-30s.

Methodology: Historical-genetic, historical-comparative and historical-system methods of research were underlain the given study.

Result: Under the leadership of Mustafa Kemal Ataturk great radical transformations in all spheres of life of the former Ottoman Empire began, namely the state system, the reform of the school and its separation from religion. All these transformations summed up the previous history of Turkey as a dependent, semi-colonial feudal state, clearing the way to modernization and renewal of all aspects of life.

Applications: This research can be used for universities, teachers, and students.

Novelty/Originality: In this research, the model of Laicism in the Republic of Turkey in the 1920-1930s is presented in a comprehensive and complete manner.
Towards an Indigenous-Informed Relational Approach to Free, Prior, and Informed Consent (FPIC)
Authors: Mitchell Terry , Arseneau Courtney , Thomas Darren , Smith Peggy
Published: October 2019

International and domestic rights frameworks are setting the stage for the full recognition of Indigenous Peoples’ rights in Canada. However, current political promises to restore Indigenous relations, to reconcile historic wrongs, and to foster mutual prosperity and well-being for all people within Canada remain woefully unfulfilled. Indigenous Peoples continue to call for full engagement with emerging Indigenous rights frameworks such as the United Nations Declaration on the Rights of Indigenous Peoples (UNDRIP) and its principles of free, prior, and informed consent (FPIC). This article discusses the key findings from a multi-year university–community research partnership with Matawa First Nations in which we collaboratively seek to advance understanding of consultation processes and Indigenous experiences of and perspectives on FPIC. The article, based on several years of dialogue and interviews and a two-day workshop on FPIC, offers insight into Indigenous perspectives on FPIC advancing an Indigenous-informed relational approach to consultation and consent seeking.
PRECARIZAÇÃO: PALAVRA FEMININA
Authors: Bertolin Patricia Tuma Martins , Da Silveira Nereida Salette Paulo
Published: October 2019

Este artigo decorreu de pesquisa financiada pelo Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) e aplicada a uma unidade produtiva de uma grande empresa do setor têxtil (fiação e tecelagem), situada no interior de São Paulo, entre 2010 e 2014. A proposta consistiu em investigar a precarização do trabalho das mulheres no “chão de fábrica”, em suas diversas manifestações (como informalidade, baixos salários, baixo grau de proteção pelo Estado, fraca representatividade sindical, longas jornadas ou jornadas parciais e excessivo controle do empregador no processo produtivo), ouvidas as vozes das operárias, buscando compreender as razões da maior exposição das mulheres à precarização.
O “COMPROMISSO SIGNIFICATIVO” (MEANINGFUL ENGAGEMENT) E A PROMOÇÃO DO PLURALISMO DEMOCRÁTICO NA CONCRETIZAÇÃO JUDICIAL DOS DIREITOS FUNDAMENTAIS SOCIAIS NA ÁFRICA DO SUL.
Authors: Kozicki Katya , Van der Broocke Bianca M. Schneider
Published: October 2019

O presente artigo pretende analisar o mecanismo procedimental denominado de Meaningful Engagement (“Compromisso Significativo”), desenvolvido pela Corte Constitucional Sul Africana a fim de promover a solução de conflitos envolvendo direitos fundamentais sociais de grupos marginalizados, por meio da interação entre aqueles efetivamente afetados pela decisão judicial e as autoridades públicas responsáveis, em busca de um acordo deliberativo que responda ao contexto e às necessidades particulares envolvidas. Utilizando o método dedutivo e, principalmente a revisão crítica de bibliografia do direito comparado sobre o tema, demonstra-se que o emprego deste instituto como estratégia jurisdicional no contexto da concretização dos direitos humanos constitucionalmente reconhecidos, representa o respeito tanto ao aspecto substantivo quanto ao procedimental da justiça, podendo negociar com sucesso as tensões entre o universalismo e o particularismo em uma sociedade democrática multiétnica e multicultural. Além disso, ao possibilitar a igual participação na construção dos significados constitucionais, o “Compromisso Significativo” promove a observância ao pluralismo enquanto corolário dos princípios democráticos liberais da igualdade e da liberdade.
Sports in the Case-Law of the European Court of Human Rights
Authors: Czepek Jakub
Published: October 2019

Sport has been an object of interest of international law on several occasions. It has also been a point of interest of regional human rights protection, for example within the legal system of Council of Europe. Recently, the European Court of Human Rights has developed its case-law concerning sport-related issues, such as football supporters related violence and prevention of events of hooliganism, anti-doping related issues or fairness of proceedings before The Court of Arbitration for Sport (CAS) in Lausanne or the protection of professional athletes’ rights in the context of anti-doping requirements. The article focuses on the ECtHR case-law relating to sport within the meaning of the  right to life (art. 2 of the ECHR), prohibition of torture of inhuman or degrading treatment or punishment (art. 3 of the ECHR), right to liberty and security (art.5 of the ECHR), right to a fair trial (art.6 of the ECHR) or right to protection of private and family life (art.8 of the ECHR).
THE PREVENTIVE DIMENSION OF THE PROTECTION OF THE RIGHT TO LIFE UNDER THE EUROPEAN CONVENTION ON HUMAN RIGHTS
Authors: Morawska Elzbieta Hanna
Published: October 2019

The aim of this article is pointing out to the process of redefining the nature, subject and structure of the obligations of States Parties to the European Convention on Human Rights in the field of the right to life (Article 2 of the Convention). The main author of the above redefinition is the European Court of Human Rights, hence it takes place during the interpretation and application of Art. 2 the Convention. As a result, in addition to primary negative obligations, the positive obligations are imposed on States. Strasbourg case law identifies a variety of positive measures that States are obliged to undertake in order to fulfill these positive obligations, including appropriate preventive measures. They are to prevent the materialisation of risks to the right to life, both in the case of threats from private individuals, as well as during the use of lethal force by State officials. The Court has not settled the precise catalog of these measures and the conditions for taking them. They are formulated case by case and are constantly being expanded. It can therefore be said that they are still in statu nascendi.
A obrigatoriedade de matrícula para a Educação Infantil: possíveis retrocessos
Authors: Lira Aliandra Cristina Mesomo , Drewinski Jane Maria de Abreu
Published: October 2019

O artigo discute a obrigatoriedade escolar para crianças de 4 e 5 anos instaurada pela Lei n. 12.796 a partir de resultados de pesquisa que objetivou acompanhar e problematizar a implementação da Lei em um município de médio porte. Teoricamente, os estudos apoiaram-se em autores que discutem a Educação Infantil como Vieira (2011), Rosemberg (2015) e Campos (2010), dentre outros. Trata-se de uma pesquisa qualitativa e quantitativa, com coleta de dados por meio de entrevistas e análise de estatísticas educacionais. Os resultados da investigação apontam que o cumprimento da legislação vem sendo feito por meio da adoção e implementação de estratégias que podem comprometer o direito das crianças à Educação Infantil de qualidade.
INTERLEUKINS - 23, -12P40 AS MARKERS OF NEURAL TISSUE DAMAGE IN NEUROSYPHILIS
Authors: Novikov Yu. A. , Ochlopkov V. A. , Indutny A. V. , Kravchenko E. N.
Published: October 2019

To study the features of cytokines in patients with various forms of neurosyphilis. The complex laboratory examination of patients with neurosyphilis and syphilis without specific lesion of the nervous system was observed in the venereological department of the OSH “Clinical Dermatological and Venereological Dispensary” in Omsk in order to determine the concentration of interleukins - 23, 12p40 in CSF and assess their relationship with the course of syphilitic infection. The presence of regularities and features in the deviation of the immune status in the examined disease was established. Analysis of immunological changes in patients’ cerebrospinal fluid showed that in patients with neurosyphilis, regardless of the presence or absence of clinical symptoms, the levels of IL-23 and IL-12p40 in CSF significantly exceed those in patients without specific lesion of the nervous system.
INFORMATIVE CHANGES IN INDICATORS OF HOMEOSTASIS TO THE ASSESSMENT OF INDIVIDUAL RISK ADAPTATION DISORDERS IN WORKERS OF THE CHEMICAL INDUSTRY
Authors: Timasheva Gulnara Vilevna , Masyagutova L. M. , Valeeva E. T. , Repina E. F.
Published: October 2019

This paper reviews the results of complex laboratory examinations among workers manufacturing fiber glass. The most pronounced and early changes in oxidative metabolism processes (reduced catalase activity, increased malonic dialdehyde) and rates of blood serum lipid metabolism indicators were determined, increased values of leukocyte indices of intoxication, violations in the immune status. Changes were detected in workers even with a small length of service (5 years) and young age (20-30 years). With increasing length of service in the workplace, the frequency of these violations increased.Based on the data obtained we have developed laboratory markers that are suitable for diagnosing early preclinical disorders among fiber glass manufacturing workers.
MARKERS OF ENDOTHELIAL DYSFUNCTION: PATHOGENETIC ROLE AND DIAGNOSTIC SIGNIFICANCE
Authors: Stepanova T. V. , Ivanov A. N. , Tereshkina N. E. , Popyhova E. B. , Lagutina D. D.
Published: October 2019

Endothelial dysfunction (ED) is considered one of the pathogenetic mechanisms of a whole range of diseases. Detection of specific biochemical markers in the blood is an effective way to ED diagnostics that characterize the vascular endothelium state. This review highlights the pathogenetic role of the factors synthesized by endotheliocytes whose level changes in biological fluids reflect violations of the endothelium basic physiological properties: vasomotor function, thromboresistance, angiogenesis regulation, barrier and adhesion functions. In particular, the participation of nitric oxide metabolites, asymmetric dimethylarginine, endothelin-1, metabolic products of arachidonic acid, von Willebrand factor, thrombomodulin, vascular endothelial growth factor, vasohibine-1 and adhesion molecules in the onset and development of ED are reviewed. The diagnostic significances of factors damaging endothelium, such as C-reactive protein, homocysteine and 8-hydroxy-2’-deoxyguanosine, are discussed. In addition, the literature data of recent years about the prospects of clinical implication the detection of the above-mentioned factors which indicates structural and functional endothelial cells damage are given. Particular attention is paid to the ED markers detection prognostic significance and the possibility of their practical use for the ED diagnosis. The search of literature for the current review was conducted in RSIC, CyberLeninka, Scopus, Web of Science, MedLine and PubMed databases from 2012 to 2018 using the following keywords: endothelial dysfunction, nitric oxide, asymmetric dimethylarginine, endothelin-1, prostacyclin, thromboxane A2, epoxyeicosatrienoic acids, von Willebrand factor, thrombomodulin, vascular endothelial growth factor, vasohibin-1, adhesive molecules, C-reactive protein, homocysteine, and 8-hydroxy-2-deoxyguanosine.
DIAGNOSTIC BACTERIOPHAGE V32 AS A TOOL FOR THE RAPID IDENTIFICATION OF ESCHERICHIA COLI SEROGROUP O157
Authors: Svetoch E. A. , Volozhantsev N. V. , Verevkin V. V. , Myakinina V. P. , Aleshkin A. V. , Kiseleva I. A. , Bannov V. A. , Krasilnikova V. M. , Borzenkov V. N. , Kartsev N. N. , Dyatlov I. A.
Published: October 2019

Bacteriophage V32, a representative of bacterial viruses of the Myoviridae family Ounavirinae subfamily, is proposed for search and identification of E. coli O157 serogroup, including Shiga-toxin producing E. coli O157:H7 (STEC O157:H7), among cultures of enterobacteria from the primary seeding of the material studied. Phage genome containes a linear double-stranded DNA of 87875 base pairs with G/C-content of 38.9% and includes 132 open reading frames (ORF). In the genome, there are no determinants of antibiotic resistance, virulence genes of STEC and other well-known pathogroups of E. coli. It has been established that phage V32 has lytic activity against all studied cultures of E. coli O157 serogroup (n=183) isolated from people and farm animals in various regions of the Russian Federation, as well as in Japan and Italy. At the same time, the phage lyses only 6 of 182 strains (3.3%) of E. coli not belonging to the O157 serogroup and is not active against strains of other enterobacteria. That is, the phage has a high specificity. The use of bacteriophage V32 as a diagnostic tool is a highly efficient, fast, cheap and simple method for identifying E. coli serogroup O157, including the serotype E. coli O157: H7, in any bacteriological laboratory without special equipment and special training of performers.
CHARACTERISTICS OF LACTOBACTERIA STRAINS, HAVING DIAGNOSTIC SIGNIFICANCE IN GYNECOLOGICAL PRACTICE
Authors: Godovalov A. P. , Danielyan T. Yu. , Karpunina T. I.
Published: October 2019

Nowadays, in the presence of wide diagnostic possibilities, laboratory diagnostics of microecological disorders of vaginal biotope are often limited to clinical data, microscopic examination results and the use of a culture method. However, with such a complex it is impossible to get an answer about the functional activity of microorganisms. The aim of investigation was to evaluate the information content of a combined study of growth parameters and the ability to produce lactic acid by clinical strains of Lactobacillus spp. to characterize the state of the microecology of the cervical-vaginal biotope. Materials and methods. Studied the growth kinetics of strains of lactobacilli isolated from the detachable posterior vaginal fornix. The concentration of lactic acid in the medium was determined using the “Lactic Acid - Olvex” kit (Russia). Samples were taken every 12 hours of cultivation. Statistical analysis of the results was performed using the methods of descriptive statistics, Student’s t-test. Results. It has been shown that 44% of Lactobacillus spp. to 72 hours of cultivation did not reach the phase of exponential growth. The remaining strains from 12-24 hours passed into the phase of exponential growth. In the production of lactic acid, the strains that are in the lag-phase did not differ from each other, since they practically did not synthesize this metabolite. Among the remaining strains that are in the phase of exponential growth, some did not produce lactic acid, others increased their lactate production every hour. Part of the strains reached the peak of acid production by 36 hours and by 72 hours some decrease in synthetic activity was observed. Conclusion. It has been shown that for most vaginal strains of Lactobacillus spp. characteristic variability of the duration of the adaptation period and the level of functional activity. In addition, only a small number of clinical strains produced lactic acid 24 hours after the start of cultivation. Therefore, to adequately assess the microecological status of the vaginal biotope, microscopic examination of both native material and cultures isolated on special nutrient media is not enough. It seems that, along with the use of modern methods of genetic analysis, the determination of in vitro growth characteristics, primarily lag-phase duration, and lactate production by lactic acid bacteria strains can clarify many issues related to the formation of dysbiotic states, in particular, in the vaginal biotope, and will also serve to increase the effectiveness of the prescribed treatment.
METHOD FOR PREDICTING PERINATAL HYPOXIC LESIONS OF THE CENTRAL NERVOUS SYSTEM IN NEWBORNS
Authors: Smirnova A. . , Borzova N. . , Sotnikova N. . , Malyshkina A. . , Bojko E. .
Published: October 2019

Perinatal lesions of the Central nervous system (CNS) in newborns occupy a leading place in the structure of perinatal morbidity and subsequent disability of children. To identify the features of the content of sRAGE in pregnant women with threatening preterm labor (UPR) in the period of 22-27 weeks, who subsequently gave birth to children with perinatal CNS lesion. Serum of venous blood of pregnant women with UPR at the term of 22-27 weeks was determined by ELISA once the content of sRAGE. If the value of sRAGE in pregnant women is 659.5 PG/ml or less, perinatal hypoxic lesions of the Central nervous system in newborns are predicted with an accuracy of 75.8% (sensitivity of 82.6%, specificity of 66.7%).
A Perspective From Indonesian Tourists: The Influence Of Destination Image On Revisit Intention
Authors: Foster Bob , Sidhartais Iwan
Published: October 2019

The tourism sector becomes a central issue in the growth of a state. Researchers have proven the critical role of domestic and foreign tourists visits in raising the state revenue. Some studies have shown the role of destination image in increasing the tourist to revisit. However, some research models have various ways of explaining the effect of destination image on the tourists’ loyalty to revisit. Therefore, this study wants to determine the effect of destination image towards tourists revisit intentions in several cities in Indonesia. This research uses the quantitative approach to answer the purpose of research. The results reveal that destination image has an impact on tourists revisit intentions. To improve the revisit intention, it is necessary for the regulators to make improvements associated with several variables that form the destination image. Besides, the tourists and travels providers must accommodate a memorable experience so that the tourists are satisfied during their visits.
Çok Kriterli Karar Verme Analizine Dayalı Tarımsal Amaçlı Arazi Kalite İndisi Uygulaması
Authors: DEDEOĞLU Mert , BAŞAYİĞİT Levent , YÜKSEL Mahmut
Published: October 2019

Bu çalışmanın amacı bölgeye özgün olarak uzman
görüşü ve çok kriterli karar destek yaklaşımlarına dayalı bir arazi kalite
indisi (AKİ) geliştirmek ve tarım arazilerinde uygulamaktır. Çalışma, Akdeniz
iklim ekolojisini temsilen 3338.61 hektar büyüklüğündeki
Muğla-Dalaman Tarım İşletme Genel Müdürlüğü arazilerine ait 7 toprak serisi ve
43 fazında yürütülmüştür. Araştırmada bölge arazilerini ve toprak
özelliklerinin bir veya daha fazlasını temsil etme niteliğine sahip toplam 13
indikatör; i) Arazi: derinlik, eğim, taşlık ve drenaj, ii) Fiziksel: faydalı su
kapasitesi, hacim ağırlığı, tekstür, iii) Kimyasal: elektriksel iletkenlik
(EC), pH, organik madde, fosfor, potasyum, toplam azot olmak üzere uzman görüşü
ve literatür bilgisi ışığında seçilmiştir. İndikatörlerin ikili
karşılaştırmasında çok kriterli karar destek yaklaşımı olan Analitik Hiyerarşik
Süreç metodu kullanılmıştır. Araştırmada, AKİ değerlendirmesi sonucu işletme
arazilerinin % 61.56’sı “çok yüksek” ve “yüksek” kaliteli olarak
sınıflandırılmış, % 35.29 büyüklüğünde arazinin tarımsal kalite sınıfı “düşük”
ve “çok düşük” nitelikte belirlenmiş ve coğrafi bilgi sistemi ortamında
haritalanmıştır. Çalışma ile bölge arazilerinin kalite son indis değerini derinlik (% 12.5), eğim (% 12), EC (% 11.1) ve bünye (% 10.7)
indikatörlerinin yüksek oranda ağırlık katsayıları ile etkilediği
belirlenmiştir. Aynı zamanda tarımsal açıdan düşük kalite değerlerine sahip
arazilerde bazı iyileştirme tedbirlerinin (drenaj kanallarının
geliştirilmesi organik madde ilavesi, taş toplama) alınması ile yüksek
kalite sınıflarına ulaşabileceği önerilmiştir.
Manajerial Berdasarkan TQM dalam Mewujudkan Mutu Layanan Perpustakaan Universitas Negeri Padang
Authors: Rahmah Elva
Published: October 2019

Total Quality Manajemen (TQM) merupakan suatu budaya organisasi yang menekankan pada upaya menciptakan mutu dan  meningkatkan mutu secara berkelanjutan melalui setiap kegiatan organisasi. Penelitian ini secara khusus bertujuan untuk: (1) mengetahui pemahaman pimpinan dan staf terhadap konsep TQM di Perpustakaan Universitas Negeri Padang (UNP); (2) memperoleh gambaran tentang bagaimana kegiatan manajerial yang berdasarkan TQM dilaksanakan untuk mewujudkan mutu layanan di Perpustakaan UNP. Metode penelitian deskriptif dengan pendekatan kualitatif. Pengumpulan data melalui observasi, wawancara dan analisis dokumen. Subyek dalam penelitian ini adalah pimpinan, kepala sub bagian, staf perpustakaan, pemustaka, kejadian, fakta, dokumen serta berbagai bentuk upaya, program atau kegiatan perpustakaan. Obyek dalam penelitian ini adalah sistem TQM yang dilaksanakan di Perpustakaan UNP. Hasil penelitian menunjukan bahwa pemahaman pimpinan dan staf terhadap konsep TQM mempengaruh kinerja karena TQM membutuhkan komitmen dan keterlibatan semua anggota organisasi secara terus menerus dan kegiatan manajerial dilaksana berdasarkan TQM sangat ditentukan kompetensi sumber daya manusia.
Evaluating Forestry Holding of Cendana Library’s Collection Using Conspectus
Authors: Handisa Rattah Pinnusa
Published: October 2019

Background of the study: Evaluating collection is required by libraries to assess the strengths and the weaknesses of collections. This research gives a benefit for libraries to improve their collection development policies. Thus, the libraries can provide adequate numbers of collections to meet the patrons’ demands.Purpose: The purpose of this report is to evaluate the forestry holdings in the Cendana library of Forest Research Institute Kupang (FRIK) by using conspectus.Method: This research is an explanatory study cases in order to describe strength and weakness of forestry holding at Cendana library. The evaluator uses the Australian conspectus due to relevancy. The conspectus has several techniques for collecting data. A checklist is used by evaluator to evaluate monographs and electronic books. In addition, the evaluator evaluates the existing collection strengths (ECS), chronological coverages, languages, and physical conditions. The evaluator records these components into the evaluative worksheet.Findings: The result reveals that the forestry holdings in Cendana Library of Forest Research Institute Kupang (FRIK) has conspectus levels in 1b. Although type of the languages become a strength, but the quantity is a weakness. The data shows that the size level of forestry holdings in the Cendana Library of Forest Research Institute Kupang (FRIK) is in the level 1 b.Conclusion: In conclusion, the collection weakness is in books’ quantities. The limited number of forestry books enforces the conspectus levels of forestry holdings in a low level (1b). Meanwhile, strengths of existing collection are the equal portions between foreign language in English and Bahasa and the physical condition of books. It is recommended that Cendana' library should increase the numbers of collections through procurement or book’s exchange program.
Estrategias de Lectura - Isabel Solé
Authors: Avendaño Vidal Yraceli Milagros
Published: October 2019

La investigación siguiente tiene como título “Influencia de las estrategias de lectura de Isabel Solé en la comprensión lectora, en los educandos de quinto grado de primaria. El objetivo es presentar la importancia de las estrategias de Isabel Solé en los procesos de lectura (antes, durante y después), y aplicarlas en la investigación para dar cuenta de la comprensión lectora.

Las estrategias se ubican dentro de los procesos de lectura. Así, en “Antes de la lectura” encontramos: la motivación para ésta, los objetivos de la lectura, la importancia de activar el conocimiento previo y el establecimiento de las predicciones sobre el texto. A continuación, en “Durante la lectura” encontramos estrategias de lectura compartida, estrategias de lectura independiente y los errores y lagunas de comprensión. Y en “Después de la lectura” encontramos la idea principal, la enseñanza del resumen en el aula, y la formulación y respuesta de preguntas. Lo mencionado forma parte de los indicadores de dicha investigación.

Al ser una investigación de tipo cuasi experimental, se prevé incrementos en los niveles de la comprensión lectora. En este caso, investigamos el nivel literal e inferencial.

En el nivel literal observamos los principales indicadores como: identificar la idea principal, precisar el espacio, tiempo y personajes, secuenciar los sucesos y hechos, recordar los pasajes y detalles del texto e identificar sinónimos.

Asimismo, en el nivel inferencial encontramos los siguientes indicadores: predecir los resultados, inferir el significado de palabras desconocidas, entrever las causas de determinados efectos, inferir el significado de frases hechas según el contexto y prever un final diferente.

La muestra empleada en esta investigación es de 66 educandos, de los cuales se tomó un grupo control de 31 estudiantes (5to C) y el grupo experimental de 35 (5to B) en el quinto grado de educación primaria.

Las mejoras se mostrarán aquí en detalle durante la presentación, análisis e interpretación de los datos. Las conclusiones muestran que se mejoró la comprensión en el nivel inferencial a través del uso de estrategias sugeridas por Isabel Solé, empleadas en las sesiones de aprendizaje en los procesos de lectura donde el niño participó activa y adecuadamente en su ejecución de las mismas.

Lo que pretendemos es demostrar que estas estrategias sirven para incrementar los niveles de comprensión lectora y la didáctica en el aula será mucho más eficaz con el planteamiento y ejecución de éstas. Considero que esto significará un aporte fundamental para mejorar la comprensión lectora.
GMOs and Economic Development in Peru: A Myth or an Opportunity?
Authors: Baxerias Diego , Banda Carol
Published: October 2019

Peru has a 10-year ban on genetically modified (GM) crops and food that was approved by the Peruvian congress in 2011. Is it scientifically justified or is it a cause and effect fallacy that will make Peru fall behind in taking advantage of this technology and its potential benefits to everyone else in the economy? In order to answer this question, a literature review was carried out to examine the three most commonly used arguments against genetically modified organisms (GMOs) by farmers and all those related to the agriculture industry, reaching the conclusion that they are not one hundred percent plausible. Further research showed the multiple, potential economic benefits that GM seeds could bring about to Peru, which are related to increased labor productivity, the development of human capital, and the expansion of renewable energy sources and its implications for trade and employment – the environmental and health benefits of GMO varieties are also discussed. This paper elaborates on such matters by applying different macro and microeconomic concepts, i.e., market structures and competition, the theory of the firm, and scarcity, among others; and provides insights about the different socio-economic realities present in Peru and possible ways to improve them.
Bio-modulating wine acidity: The role of non-Saccharomyces yeasts
Authors: Vilela Alice
Published: October 2019

In recent years, wine consumers have been looking for fruitier wines, with less ethanol, but presenting a good balance in terms of mouthfeel. However, due to the effects of global climate change, wines can be more alcoholic and flatter in terms of acidity. If in the past, non-Saccharomyces yeasts were often considered as spoilage yeasts, now they are used to modulate wine composition, namely in terms of aroma and acidity. In this article, the ability of some non-Saccharomyces yeasts to modulate wine acidity is reviewed.
Defoliation of the vines before or after berry set: Physiological consequences and qualitative factors
Authors: Verdenal Thibaut , Zufferey Vivian , Dienes-Nagy Agnès , Bourdin Gilles , Gindro Katia , Spring Jean-Laurent
Published: October 2019

Defoliation of the vines consists of eliminating the leaves in the grape bunch zone in a more or less intensive manner. It is a long-proven prophylactic technique that has seen a renewed interest in the current context of the reduction of phytosanitary inputs. However, several questions remain. Which is the optimal period? What is the ideal intensity? What are the risks? Is the mechanization of this process a feasible option? Agroscope has been undertaking defoliation trials in Switzerland since 2010 in order to shed light on these questions.
Viticulture in a changing climate: solutions exist
Authors: Van Leeuwen Cornelis , Roby Jean-Philippe , Ollat Nathalie
Published: October 2019

Grape growers have always cultivated vineyards in challenging environments, adapting their practices to sometimes very difficult local conditions. Climate change, as a new player, is modifying the terroirs’ characteristics rapidly and irremediably, giving viticulturalists major new challenges to face.
Produits "Biocontrôle" : une efficacité toute relative contre le botrytis.
Authors: Dewasme Coralie , Mary Séverine , Roby Jean-Philippe
Published: October 2019

Le botrytis impacte le rendement et la qualité des moûts. Pour se prémunir de ces dégâts, les viticulteurs axent la lutte contre cette maladie sur l’application de produits phytosanitaires et sur la mise en œuvre de mesures prophylactiques.  En climat océanique, un ou deux traitements annuels à base de produits dangereux pour l’environnement et la santé de l’opérateur, et souvent onéreux, sont couramment appliqués. Les produits de « biocontrôle » pourraient être une alternative intéressante à ces derniers mais, comme en témoigne cette étude, ils ne sont pas aussi performants que les fongicides classiques.
Brettanomyces bruxellensis : où en sommes-nous ?
Authors: Lonvaud-Funel Aline
Published: October 2019

Dès les années 1950, B. bruxellensis apparait dans les inventaires de levures de moûts et de vins, et rapidement, on lui attribue des altérations du vin. Beaucoup plus tard, les phénols volatils produits par ces levures sont identifiés comme la cause de déviations sensorielles. Leur présence est de plus en plus prégnante, surtout pendant l’élevage en barriques. Le sulfitage est le moyen idéal d’éradication, mais s’avère quelquefois insuffisant. Particulièrement bien adaptée au vin, B. bruxellensis est aujourd’hui au centre des préoccupations des vinificateurs et des microbiologistes.
Ethanol sprays to release grapevine bud dormancy: a potential alternative to cyanamides
Authors: Chervin Christian , Fennell Anne
Published: October 2019

Aim: Grape growers sometimes use cyanamides (calcium or hydrogen) to release bud dormancy in warm climate regions, where the chilling requirement has not been met during winter. However, these products can cause damage to plants and are dangerous to handle, so alternatives would be welcomed by growers. Connections between metabolisms of ethanol, ethylene and cyanide revealed by previous studies led us to test the potential of ethanol sprays on bud break and early shoot growth.Methods and results: Trials were performed over three years on Vitis vinifera grapevines trained in Guyot or cordon, and on cuttings in growth chambers. Cultivars used in the studies included Cabernet-Sauvignon, Syrah and Ugni blanc. The results show that ethanol can advance bud break of all three cultivars at concentrations ranging from 2.5 to 10 % ethanol in water. Ethanol stimulates bud development in both Guyot and cordon training systems. However, the timing of ethanol application is crucial, and late spring season applications reduce the effectiveness of the treatment.Conclusions: Observations were performed over three different seasons. The trials revealed that ethanol sprays can advance bud break of different Vitis vinifera vines, trained with cane or spur systems.Significance and impact of the study: Climate change impacts dormancy release, making it an increasingly important issue over the next few decades. An alternative to the dangerous use of cyanamides to promote bud break would greatly help growers. These preliminary results with ethanol are promising but should lead to trials in various growing areas and with various cultivars in order to confirm their potential for viticulture.