bluuebunny/crossref_metadata_2025 huggingface dataset:
Enhancing Reliability in Wind Turbine Power Curve Estimation
Authors: Marti-Puig Pere , Hernández José Ángel , Solé-Casals Jordi , Serra-Serra Moisès
Published: February 2024

Accurate power curve modelling is essential to continuously evaluate the performance of a wind turbine (WT). In this work, we characterize the wind power curves using SCADA data acquired at a frequency of 5 minutes in a wind farm (WF) consisting of 5 WTs. Regarding the non-parametric methods, we select artificial neural networks (ANNs) to make curve estimations. Given that, we have the curves provided by the manufacturer of the WTs given by some very precisely measured pair of wind speed and power points. We can evaluate the difference between the manufacturer characterization and the ones estimated with the data provided by the SCADA system. Before the estimation, we propose a method of filtering the anomalies based on the characteristics provided by the manufacturer. We use three-quarters of the available data for curve estimation and one-quarter for the test. One WT suffered a break in the test part, so we can check how the test estimates reflect this problem in its wind-power curve compared to the estimations obtained in the WTs that worked adequately.
C4d in IgA Nephropathy; a Personal Experience
Authors: Nasri Hamid
Published: February 2024

IgA nephropathy (IgAN) is a kidney disease that is characterized by the deposition of IgA (immunoglobulin A) in the kidney tissue, leading to inflammation and damage. This disease is a common chronic glomerulopathy that affects people worldwide (1). Therefore, it is crucial to identify factors that worsen the disease, monitor its activity, and predict appropriate treatments. Complement component 4d (C4d) is a protein that is involved in the activation of the complement system, which is a part of the immune system.
Optimization of Solid-State Fermentation Process of Radix Ranunculi ternate using Response Surface Method and Study of its Antioxidant, Hypoglycemic Activities
Authors: He Dingxuan , Duan Dingyu , Lv Xueyan , Xiong Baihui , Li Zhuojia , Zhang Shaojun , Cai Jing , Qiao Xinrong , Chen Qiong
Published: February 2024

Objective: The aim of this study was to optimize the fermentation process of Radix Ranunculi ternate via microbial fermentation and analyze the changes in the contents of the main components, the antioxidant and hypoglycemic capacities of the extract before and after fermentation. Methods: The solid-state fermentation process was optimized using single-factor tests and the response surface method, with the yield of the alcohol extract of R. ternate as an evaluation index. Results: The best fermentation process was optimized using solid-state endophytic fungus fermentation technology as follows: strain addition ratio of Chaetomium globosum/Fusarium equiseti =1:1, fermentation for 5 d, sieve size of 40 mesh, liquid/material ratio of 0.8:1 mL·g−1, fermentation temperature of 31 °C, and inoculation amount of 7.5%. Under the optimized conditions, the contents of the water-soluble extract and total polysaccharides decreased by 12.71% and 12.95%, respectively, in the fermentation, The contents of ethanol-soluble-extract, flavonoids, saponins, polyphenols, organic acids, and total amino acids of fermented R. ternate increased by 19.77%, 57.14%, 79.67%, 14.29%, 17.63% and 3.82%, respectively, and the scavenging rate for DPPH, ABTS+, ·OH free radicals and inhibitory rate for α-amylase also increased by 19.02%, 14.17%, 7.53% and 34.54%, respectively, compared with unfermented R. ternate. Conclusions: Solid-state fermentation opens new avenues for the development and application of R. ternate as natural antioxidant and hypoglycemic food.
Non‐Invasive Heart Failure Evaluation with Wearable Signals and Machine Learning Algorithms
Authors: Victor Odeh Adeyi , Chen Yifan , Wang Wenyan , Ding Xiaorong
Published: February 2024

Heart failure is a prevalent cardiovascular condition with significant health implications, necessitating effective diagnostic strategies for timely intervention. This study explores the potential of continuous monitoring of non-invasive signals, specifically integrating Photoplethysmogram (PPG) and Electrocardiogram (ECG), for enhancing early detection and diagnosis of heart failure. Leveraging a dataset from the MIMIC-III database, encompassing 682 heart failure patients and 954 controls. Feature selection techniques were used to systematically select key features which were identified for their clinical relevance and significance in capturing cardiovascular dynamics and to reduce computational complexity and to decrease the chance of overfitting the ML algorithms. These features are then utilized to train and evaluate machine learning algorithms, resulting in a model with an impressive accuracy of 98%, sensitivity of 97.60%, specificity of 96.90%, and precision of 97.20%. The integrated approach outperforms single-signal strategies, showcas-ng its potential for early, precise, and non-invasive heart failure diagnosis. Furthermore, the study underscores the significance of continuous monitoring through wearables, emphasizing the benefits of integrating multiple signals for a comprehensive evaluation of cardiovascular health. The proposed approach holds promise for implementation in hardware systems to enable continuous monitoring, aiding in early detection and prevention of critical health conditions.
GWAS in a Collection of Bulgarian Old and Modern Bread Wheat Accessions Uncovers Novel Genomic Loci for Grain Protein Content and Thousand Kernel Weight
Authors: Kartseva Tania , Aleksandrov Vladimir , Alqudah Ahmad M. , Arif Mian Abdur Rehman , Kocheva Konstantina , Doneva Dilyana , Prokopova Katelina , Börner Andreas , Misheva Svetlana
Published: February 2024

Genetic enhancement of grain production and quality is a priority in wheat breeding projects. In this study, we assessed two key agronomic traits - grain protein content (GPC) and thousand kernel weight (TKW) - across 179 Bulgarian contemporary and historic varieties, and landraces in three growing seasons. Significant phenotypic variation existed for both traits among genotypes and seasons, and no discernible difference was evident between the old and modern accessions. To understand the genetic basis of the traits, we conducted a genome-wide association study with MLM using phenotypic data from the crop seasons, best linear unbiased estimators, genotypic data from the 25K Infinium iSelect array, and a Bonferroni-adjusted p-value. As a result, 776 significant quantitative trait nucleotides (QTNs) organized into quantitative trait loci were discovered, including 25 loci associated with GPC, and 35 loci linked to TKW. Additionally, 14 environmentally stable QTNs were identified for TKW. Certain loci on chromosomes 2A, 3A, and 6B favorably in-fluenced GPC, while the locus on chromosome 6D impacted TKW positively. These loci may reflect novel associations to the two traits. Annotations for proteins involved in the remobilization of carbon and nitrogen from vegetative tissues to developing grain during senescence, as well as in the following buildup of resources required for seed germination, have been found for selected pu-tative candidate genes. These include genes coding for 11S globulin seed storage protein, glutamine synthetase, metalloendopeptidase, components of the ubiquitin/proteasome system, sucrose transporter, alpha-amylase, NAC and bZIP transcription factors. Our findings highlight promising genomic regions for targeted breeding programs aimed at improving grain yield and protein content.
Generalized Pareto-Type Distribution and Income Inequality: An Extension of Gibrat’s Law
Authors: Tao Yong
Published: February 2024

Motivated by empirical observations, we propose a possible extension of Gibrat's law. By applying it into the random growth theory of income distribution (Gabaix, 2009), we find that the income distribution is described by a generalized Pareto-type distribution (GPD) with three parameters. We observe that there is a parameter /elta in the GPD that plays a key role in determining the shape of income distribution. By using the Kolmogorov-Smirnov test, we empirically show that, for typical market-economy countries, /elta is close to 0 significantly, such that the income distribution is characterized by a two-class pattern in which the bottom 90% of the population is approximated by an exponential distribution and the richest 1%~3% is approximated by an asymptotic power law. However, we empirically find that, for China both in planned economy period and in early stages of market reformation (from 1978 to 1990), /elta is significantly deviated from 0, such that the bottom of the population no longer conforms to an exponential distribution.
Towards Real-Time Railroad Inspection Using Directional Eddy Current Probe
Authors: Mussatayev Meirbek , Alanesi Mohammed
Published: February 2024

In the field of railroad safety, effective detection of surface cracks is critical, necessitating reliable, high-speed non-destructive testing (NDT) methods. This study introduces a hybrid Eddy Current Testing (ECT) probe, specifically engineered for railroad inspection, to address the common issue of 'lift-off noise' due to varying distances between the probe and test material. Unlike traditional ECT methods, this probe integrates transmit and differential receiver coils, aiming to enhance detection sensitivity and minimize lift-off impact. The research involves optimizing the ECT probe through various driver coils, focusing on three key aspects: a) explains methodology of real-time data processing algorithm; b) probing the frequency range near the receiver coil's electrical resonance, c) assessing sensitivity changes across different lift-off distances. The experimental outcomes indicate that the newly designed probe with figure 8-shape driver coil significantly improves sensitivity in detecting surface cracks on railroads. It achieves an impressive signal-to-noise ratio (SNR) exceeding 60 for defects with minimal dimensions of 0.8 mm in width and depth. This study represents a notable advancement in NDT techniques, with profound implications for enhancing railroad safety by improving crack detection efficiency.
Enabling Efficient On-Edge Spiking Neural Network Acceleration with Highly Flexible FPGA Architectures
Authors: López-Asunción Samuel , Ituero Pablo
Published: February 2024

Spiking neural networks (SNNs) promise to perform tasks currently done by classical artificial neural networks (ANNs) faster, in smaller footprints and using less energy. Neuromorphic processors are set out to revolutionize computing at a large scale, but the move to edge-computing applications calls for finely-tuned custom implementations to keep pushing towards more efficient systems. To that end, we have examined the architectural design space for executing spiking neuron models on FPGA platforms, focusing on achieving ultra-low area and power consumption. This work presents an efficient clock-driven spiking neuron architecture used for the implementation of both fully-connected cores and 2D convolutional cores, which rely on deep pipelines for synaptic processing and distributed memory for weight and neuron states. With them, we have developed an accelerator for an SNN version of the LeNet-5 network trained on the MNIST dataset. At around 5.5 slices/neuron and only 348 mW, it is able to use 33% less area and 4 times as less power per neuron as current state-of-the-art implementations while keeping low simulation step times.
Estimating Wastewater Dilution Using Chemical Markers and Incomplete Flow Measurements: Application to Normalisation of SARS-CoV-2 Measurements
Authors: Jones Owen D. , Baldwin Amy J. , Perry William B. , Wilde Henry , Durance Isabelle , Jones Davey L. , Weightman Andrew
Published: February 2024

We construct a Bayesian estimator for the dilution of a wastewater sample, and use it to estimate the prevalence of SARS-CoV-2 in Wales using data from the Wales Environmental Wastewater Analysis and Surveillance for Health project (WEWASH). In Wales wastewater is diluted by rainwater so an estimate of the level of dilution is required if we are to normalise sample measurements of disease markers such as SARS-CoV-2 RNA. We consider the situation where flow measurements are available, but will regularly be unreliable because of the action of combined sewer outflows, which divert wastewater away from treatment plants when the flow is excessive. However we also have proxies for the flow from various chemical markers, whose level per unit of population is fixed. The new estimator has multiple advantages compared to existing procedures: credible intervals for the estimates; optimal weighting of the chemical markers; systematic handling of missing and censored values; and model based smoothing without lags.
Zinc Storage Performance of Oxygen-Deficient NH4V3O8: Theoretical and Experimental Study
Authors: Lin He , Cai Xuanxuan , Zhang Yu
Published: February 2024

Using density functional theory (DFT), the density of states of NH4V3O8 (NVO) was analyzed pre and post-oxygen defects (Od) formation. The findings revealed a reduced bandgap in NVO after Od introduction, emphasizing the role of Od in enhancing conductivity of the material, thus improving its electrochemical attributes. Through the water bath method, both NVO and its oxygen-deficient counterpart, (NH4)2V10O25⸱8H2O (NVOd), were synthesized as potential cathode materials for aqueous zinc-ion batteries (AZIBs). Experimental outcomes resonated with DFT predictions, highlighting the beneficial role of oxygen defects in boosting electrical conductivity. Notably, the refined material displayed a remarkable capacity of 479.3 mAh g-1 at 0.1 A g-1, underscoring its promise for advanced energy storage solutions.
Electrochemical Characterization of Diffusion in Polymeric vs. Monomeric Solvents
Authors: PORAT ZE'EV
Published: February 2024

Polymer electrolyte was used as a medium for testing the performance of microband electrodes under conditions of linear diffusion. Cyclic voltammetry and chronoamperometry experiments were performed in such viscous medium, where diffusion rates are much slower than in fluid solutions. Confirmation of the existence of such conditions from the log i vs. log v or log i vs. log t relationships in the current equation always yielded values lower than the expected value of 0.5. This could indicate impure linear diffusion profile, i. e. some contribution from radial diffusion (edge effect). However, performing these tests in monomeric solvents of similar viscosities, such as glycerol or propylene glycol, gave the desired value of 0.5. These results lead to the conclusion that current equations which are based on Fick’s laws may not be applicable for polymer electrolytes, where various obstruction to diffusion make it a more complicated process than in monomeric solvents.
Syndrome of megalencephaly, postaxial polydactyly, polymicrogyria, and hydrocephalus: a rare case
Authors:   I.K.Akhunbaev Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan, Zhihareva V.V. , Uzakbayev C.K. ,   J.Balasagyn Kyrgyz State National University, Bishkek, Kyrgyzstan, Abdurasulova Z.R. ,   I.K.Akhunbaev Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan, Nazhmudinova D.D. ,   I.K.Akhunbaev Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan
Published: February 2024

We report an exceedingly rare case of megalencephaly, postaxial polydactyly, polymicrogyria, and hydrocephalus in a 9-monthold infant. The information in the article will help doctors to perform adequate differential diagnostic search in time. We describe the history of this syndrome discovery and provide a detailed description of the results of magnetic resonance imaging Key words: congenital abnormalities of the central nervous system, hydrocephalus, megalencephaly, perinatal diagnosis, fetus, polymicrogyria, postaxial polydactyly
The real-world effectiveness of glecaprevir/pibrentasvir in HCV-infected adolescents 12–17 years of age in Russia (“DETI-2” study)
Authors:   Samara City Hospital No 10, Samara, Russian Federation, Strebkova E.A. , Khaertynova I.M. ,   A.F.Agafonov Republican Clinical Infectious Diseases Hospital, Kazan, Russian Federation,   Kazan State Medical Institute, Kazan, Russian Federation, Bhagat A. ,   AbbVie, Singapore, Singapore, Milenin D.O. ,   AbbVie, Moscow, Russian Federation, Galagan A.V. ,   AbbVie, Moscow, Russian Federation, Odinaeva N.D. ,   Research Clinical Institute of Childhood of the Ministry of Health of the Moscow Region, Moscow, Russian Federation,   M.F.Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russian Federation
Published: February 2024

The introduction of interferon-free combinations made it possible to effectively conduct antiviral therapy of chronic infection caused by hepatitis C virus (HCV) first in adults and later in adolescents. Glecaprevir/pibrentasvir (GLE/PIB) allowed to achieve sustained virological response (SVR12) in 100% (47/47) of adolescents in the DORA clinical trial. In the meantime there is insufficient data describing the effectiveness of GLE/PIB in adolescents in real clinical practice in Russia. Objective. Evaluation of the effectiveness of GLE/PIB in the treatment of chronic hepatitis C in adolescents 12–17 years of age in real clinical practice in the Russian Federation. Patients and methods. This prospective multicenter observational study enrolled adolescents (12–17 years old) chronically infected with HCV who were prescribed GLE/PIB for 8–16 weeks according to the label approved in the Russian Federation. Efficacy was evaluated based on the sustained virological response rate (SVR12), defined as the HCV RNA level < 50 IU/ml (or undetectable) 12 weeks after the last dose of GLE/PIB. Results. Of the 99 patients enrolled in the study, 92 received GLE/PIB for 8 weeks and 7 for 16 weeks. The overall SVR12 rate was 96.77% (90/93). In subgroups receiving 8- and 16-week courses of therapy, the efficacy was 96.51% (83/86) and 100% (7/7), respectively. SVR was achieved in 96.43% (81/84) of treatment-naive patients, and in 100.00% (9/9) of treatmentexperienced patients. Adverse events (AEs) were reported in 7.07% of patients (7/99), while no AEs of the 3rd degree of severity were observed, as well as no serious adverse events. All patients who did not achieve SVR12 had been diagnosed with stage 4 HIV infection. Conclusion. GLE/PIB was highly effective and well tolerated by adolescents infected with HCV in real clinical practice in Russia, which corresponds to the results previously obtained in the DORA clinical trial. Key words: hronic hepatitis C, hepatitis C virus, glecaprevir, pibrentasvir, SVR12, adolescents
Los atajos de la cuarta revolución industrial a la democracia: una reflexión de lecciones aprendidas en clave de Lafont y Berlin
Authors: Martínez Garbiras María Margarita , Sánchez-Huertas Luis Fernando
Published: February 2024

Son numerosos los trabajos interesantes sobre la democracia y sus crisis que se han producido en los años recientes. Forman parte de una discusión que en los términos de Sartori está abierta, y quizás es porque el concepto democraciasufre de manera más común el estiramiento conceptual. Este escrito busca presentar un análisis de la democracia deliberativa y los atajos de la democracia, teniendo en cuenta los planteamientos de la profesora Lafont, enmarcando esta discusión en el contexto de la cuarta revolución industrial, con el fin de analizar cuáles son los atajos que la tecnología le propone a la democracia contemporánea, y finalmente exponer una reflexión a manera de lección aprendida.
A cegueira deliberada como causa configuradora de ato de improbidade administrativa: indagações preliminares
Authors: Gesta Leal Rogério
Published: February 2024

O problema que pretendemos indagar neste texto é o atinente à adequação, ou não, do instituto da cegueira deliberada, muito utilizada no âmbito do Direito Penal, para caracterizar determinados atos de improbidade administrativa. Em face disto, nossa hipótese é a de ser possível reconhecer comportamentos de agentes que evitam conhecer elementos configuradores da ilicitude de suas ações ímprobas como cegueira deliberada, capaz de responsabilizá-los nos termos da lei de regência desta matéria.
A nova onda do imperador: negação do resultado das urnas e a fragilização da democracia eleitoral
Authors: Araújo Eduardo Borges Espínola , Kreuz Leticia Regina Camargo
Published: February 2024

O artigo debruça-se sobre um comportamento tornado comum no contexto de crise da democracia liberal: a negação eleitoral. Sem prova, políticos de inclinações autoritárias e populistas alegam que teriam sido vítimas de fraude nas eleições, tenham saído vitoriosos ou não. É o caso de Donald Trump, Jair Bolsonaro, Benjamin Netanyahu, entre outros que, em comum, tem a completa falta de provas das alegações. A partir de uma metodologia lógico-dedutiva, a partir da análise de casos e de revisão bibliográfica acerca do tema, a pesquisa apresenta a narrativa do negacionismo eleitoral. Em seguida, será demonstrado o perverso efeito que esse comportamento possui sobre um dos principais objetivos das eleições: a transmissão pacífica do poder político. E assim o é porque o negacionista eleitoral, com suas alegações infundadas, inviabiliza o encerramento definitivo da disputa. Por fim, o artigo cuidará de mostrar o desafio que o negacionismo impõe à administração eleitoral, porque mobilizam o estado de espírito dos eleitores. Conclui-se que a negação eleitoral é prática autoritária, que enfraquece os pressupostos da democracia constitucional e afeta a confiança da população na higidez do processo eleitoral, afetando diretamente a transição pacífica do poder político que deveria ser consequência de um processo eleitoral.
Evaluating Patient and Surgeon Characteristics Associated with Care Cost and Outcomes for Knee and Hip Replacement Procedures
Authors: Dun Chen , Rumalla Kranti C. , Walsh Christi M. , Escobar Carolina
Published: February 2024

Background:

The role of physician credentialing has been widely considered in quality and outcome improvement studies. However, the association between surgeon characteristics and health-care costs remains unclear.

Methods:

Our objective was to determine the association of orthopaedic surgeon characteristics with health outcomes and costs, utilizing Medicare data. We used 100% Fee-for-Service Medicare data from 2015 to 2019 to identify all patients ≥65 years of age who underwent 2 common orthopaedic surgical procedures, total hip and knee replacement. After determining whether the patients had been readmitted after discharge from their initial admission for surgery, we computed 3 metrics of total medical expenditure: the costs of the initial surgery admission and 30-day and 180-day episode-based bundles of care. Hierarchical linear regression and logistic regression models were used to evaluate patient and surgeon characteristics associated with care costs and the likelihood of readmission.

Results:

We identified 2,269 surgeons who performed total knee replacements on 298,934 patients and 1,426 surgeons who performed total hip replacements on 204,721 patients. Patient characteristics associated with higher initial surgery costs included increasing age, female sex, racial minority status, and a higher Charlson Comorbidity Index. Surgeon characteristics associated with lower readmission rates included practice in the Northeast region and a higher patient volume; having malpractice claims was associated with higher readmission rates.

Conclusions:

A higher volume of patients treated by the orthopaedic surgeon was associated with lower overall costs and readmission rates. Information on surgeons’ malpractice claims and annual volume should be made publicly available to assist patients, payer networks, and hospitals in surgeon selection and oversight. These results could also inform the guidelines of physician credentialing organizations.

Level of Evidence:

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Periodic Maintenance Analysis of Diesel Motor Generator Set 900 kVA Power as Backup Energy
Authors: Rofiq Salam Rois Nur , Widodo Edi
Published: February 2024

In the realm of backup power sources, maintaining the efficiency of generators is paramount for ensuring reliability and availability during power outages. This study aims to evaluate generator efficiency through routine maintenance analysis, adhering to regulatory frameworks outlined in regulations such as Regulation No. 29 of 2012 and Electricity Law No. 30 of 2009. By employing methods including Mean Time Between Failures (MTBF) and assessing Actual Operating Time (AOT) against Specified Operating Time (SOT), this research determines the availability and compliance of each generator. Results highlight the importance of stringent regulatory compliance in enhancing the functionality and reliability of generators, thereby emphasizing the significance of routine maintenance for improved operational health.
Highlight :

Adherence to regulatory frameworks ensures operational compliance and reliability.
Routine maintenance analysis enhances generator efficiency and availability.
Availability assessment methods such as MTBF and AOT provide insights into operational health.

Keywords: Generator reliability, Routine maintenance, Regulatory compliance, Availability assessment, Backup power sources
Çalışanların A Tipi Kişilik Özelliklerinin Yengeç Sendromu Üzerine Etkisi: Hizmet Sektörü Çalışanları Üzerine Bir Araştırma
Authors: DURMUŞ Şerif , ÖZYILMAZ Ahmet Fatih
Published: February 2024

Çalışanların kişilik özellikleri, onların örgüt ortamındaki tutum ve davranışlarını etkilemektedir. Çalışanların kişilik özelliklerinden kaynaklı takındıkları tutum ve sergilemiş oldukları davranışların örgütsel açıdan olumlu veya olumsuz sonuçları bulunmaktadır. Bu bağlamda insan ilişkilerinin yoğun olduğu hizmet sektörü çalışanlarının kişilik özelliklerinin ve potansiyel davranış kalıplarının bilinmesi önemli bir konu olmaktadır. Bu noktadan hareketle araştırmanın temel amacı, hizmet sektörü çalışanlarının A tipi kişilik özelliklerinin yengeç sendromu üzerindeki etkisinin belirlenmesidir. Bu amaçla Karaman ilinde hizmet sektöründe çalışan 263 kişiye ulaşılmıştır. Veri toplamak için anket tekniğinden yararlanılmıştır. Toplanan veriler SPSS ve AMOS programları vasıtasıyla çözümlenmiştir. Analiz kapsamında normallik testi, doğrulayıcı faktör analizi (DFA), t-test, ANOVA testi, korelasyon ve regresyon analizi uygulanmıştır. Elde edilen bulgulara göre A tipi kişilik özelliğinin yengeç sendromu üzerinde anlamlı ve pozitif bir etkisinin olduğu saptanmıştır. Ayrıca çalışanların A tipi kişilik özelliği ve yengeç sendromu davranışlarına ilişkin görüşlerinin cinsiyet ve yaş grupları açısından farklılık gösterdiği saptanmıştır.
Bütçe Hakkının Etkinliği Bakımından Türkiye ve Güney Kore Karşılaştırılması
Authors: ÇALIŞKAN Emine , ŞAHİN İPEK Elif Ayşe
Published: February 2024

Magna Carta ile başlayan bütçe hakkının tarihsel gelişim süreci; vergileme hakkının elde edilmesi, harcamaları onaylama hakkı ve nihayetinde yıllık onaylama hakkı olmak üzere üç safhadan oluşmaktadır. Bütçe hakkı ile gelir toplama, harcama yapma yetkisi yasama organı tarafından bütçe aracılığı ile yürütme organına verilmektedir. Çalışmada bütçe hakkının kullanımını etkileyen ve OECD tarafından yapılan “OECD Ülkelerinde Bütçeleme ve Kamu Harcamaları 2019” anketinde de yer alan faktörler, Güney Kore ve Türkiye’deki mevzuatlardan yola çıkılarak değerlendirilmiştir. Seçilen faktörler temelinde; Güney Kore’de bütçe hakkı uygulaması ile Türkiye’nin değişen hükümet sistemindeki bütçe hakkının kullanımı karşılaştırılmıştır. Çalışma sonucunda Güney Kore ve Türkiye’deki yasama organının bütçe hakkını kullanma kapasitesi ülkede uygulanan hükümet sistemlerinden ziyade ülkede uygulanmakta olan yasal düzenlemeler, ülkelere özgü siyasi ve kültürel etkiler tarafından belirlendiği görülmüştür.
Sensitive Determination of Hydrochlorothiazide Drug in the Various Samples Via Developed Method of CFIA System
Authors: Hanooan Wasan A. , Qassim Bushra B.
Published: February 2024

تحديد عقار هايدروكلوروثيازايد في العينات الصيدلانية والبايولوجية الادرار باستخدام تقنية جديدة لتحليل الحقن الجرياني المستمر وهي سريعة , بسيطة ,اقتصادية وحساسة. المعقد المتكون بواسطة تفاعل هيدروكلوروثيازايد مع اورثوفانيلين داي امين مع فيروسيانيد البوتاسيوم لانتاج ناتج ملون برتقالي عند طول موجي 480 نانومتر كان  الاساس للطريقة المطورة . العوامل الكيميائية و الفيزيائية  الاخرى التي لها تؤثر على استقرارية  وتطور الناتج الملون المستخدم في هذه الطريقة المطورة  تضمنت  حجم العينة,معدل التدفق,تركيز الكاشف وملف التفاعل ,خطية الطريقة المقترحة كانت 5-150 مايكروغرام .مل-1   ومعامل الارتباط كان0.9988  و كانت قيم النسبة المئوية للأسترداد  والخطاء النسبي٪100.88, 0.88 على التوالي  .قيم حد الكشف والحد الكمي 2.622,7.97 . نمذجة العينة  90 نموذج لكل ساعة تم استخدام النهج الجديد بشكل فعال لتحديد الهايدروكلورثيازايد في العينات النقية ,البايولوجية وا لصيدلانية
Removal of Some Heavy Metals from Polluted Water Using New Schiff Base for Polyacrylamide with Zeolite Nanocomposites
Authors: Abdulsada Zainab Sabeer , Hassan Sahar S. , Awad Sanaa Hitur
Published: February 2024

تضمن هذا العمل تحضير ليكند قاعدة شيف جديدة مشتقة من مادة البولي أكريلاميد والكلوترالديهايد [(2S, 2'S) – N, N' - (pentane-1, 5-diylidene) bis (2- methylbutan amide)]  مع بعض المعادن الثقيلة (Cr + 3 Mn + 3 , Fe + 3 , ,Co + 2,  Ni + 2 ,Cu + 2  Zn + 2 , Cd + 2,) لتنتج المعقدات المقابلة. تم تشخيص قواعد شيف ومعقداتها المعدنية بأستخدام طيف الأشعة تحت الحمراء والأشعة المرئية وفوق البنفسجية، والتوصيلية ,وقيم المغناطيسية والتحليل الحراري الوزني وحيود الأشعة السينية ومجهرالمسح الالكتروني ومجهر القوة الذرية. تم استخدام البوليمرات المحضرة في إزالة عدد من العناصر من المياه الملوثة المسحوبة من المياه الصناعية لمحطتي الطاقة الكهربائية في الدورة وجنوب بغداد وتقدير التراكيز الضئيلة لتلك العناصر قبل وبعد استخدام القاعدة المحضرة بواسطة مطيافية الامتصاص الذري.
Hetero-associative Memory Based New Iraqi License Plate Recognition
Authors: Hasan Rusul Hussein , Aboud Inaam Salman , Hassoon Rasha Majid , Khioon Ali saif aldeen Aubaid
Published: February 2024

نتيجة للتطورات الأخيرة في أبحاث الطرق السريعة بالإضافة إلى زيادة استخدام المركبات، كان هناك اهتمام كبير بنظام النقل الذكي الأكثر حداثة وفعالية ودقة (ITS) في مجال رؤية الكمبيوتر أو معالجة الصور الرقمية، يلعب تحديد كائنات معينة في صورة دورًا مهمًا في إنشاء صورة شاملة. هناك تحدٍ مرتبط بالتعرف على لوحة ترخيص السيارة (VLPR) بسبب الاختلاف في وجهة النظر، والتنسيقات المتعددة، وظروف الإضاءة غير الموحدة في وقت الحصول على الصورة والشكل واللون، بالإضافة إلى الصعوبات مثل ضعف دقة الصورة ، الصورة الباهتة ، الإضاءة السيئة، التباين المنخفض، يجب التغلب عليها. اقترحت هذه الورقة نموذجًا باستخدام تعديل الذاكرة الترابطية ثنائية الاتجاه  (MBAM)، وهي نوع واحد من الذاكرة الترابطية غير المتجانسة، وتعمل MBAM على مرحلتين)مرحلتي التعلم والتقارب) للتعرف على اللوحة، ويمكن لهذا النموذج المقترح التغلب على تلك الصعوبات بسبب قدرة الذاكرة الترابطية لـ MBAM على قبول الضوضاء وتمييز الصور المشوهة، وكذلك سرعة عملية الحساب نظرًا لصغر حجم الشبكة. نتيجة دقة تحديد منطقة اللوحة هي 99.6٪، ودقة تجزئة الأحرف 98٪، والدقة المحققة للتعرف على الأحرف هي100 ٪ في ظروف مختلفة.
Single Nucleotide Polymorphism (SNP) rs2229569 with L Selectin Gene Expression in Iraqi Female during in vitro Fertilization Program.
Authors: Rashid Raghad Hameed , Almohaidi Asmaa M. Salih , Ali Alia Hussain
Published: February 2024

يُعرف العقم بأنه أحد مشاكل الصحة الإنجابية الرائدة في مناطق مختلفة من العالم. يعتبر الإخصاب في المختبرأحد أكثر علاجات العقم فعالية. في الدراسة الحالية ، تم تحديد دور جين SELL ، وخاصة تعدد الأشكال rs2229569 ، من حيث الانغراس ومستوى التعبير. اشتملت الدراسة على 67 انثى خضعن لدورة إخصاب في المختبر ، مقسمة إلى مجموعتين رئيسيتين: مجموعة الإناث التي فشلت عملية الزرع ومجموعة الإناث الناجحة في عملية الزرع. تم جمع عينات الدم من مجموعتي الاناث. بعد استخلاص الدنا من الدم وتضخيم  الحمض النووي عن طريق تفاعل البلمرة المتسلسل  ، تم إرسال العينات لتحليل التسلسل ، وتم تحديد SNP rs2229569  التي اظهرت  ثلاثة أنماط وراثية. كانت مجموعة الفشل منحرفه عن H.W.E. ، وكانت مجموعة النجاح في اتفاق مع H.W.E. وفقًا لقيم مربع كاي ((X2 = 11.60 1.58، تشير الفروق المعنوية في مجموعة الفشل إلى تأثير العقم في مجتمع الدراسة. تُظهر نسبة الأرجحية لـ rs2229569 أن أليل T كان (2.09) ، لذلك قد يمثل T allele أليل المخاطرة لعمليةفشل الزرع .أخيرًا ، أظهر جين SELL مستوى تعبيرًا منخفضًا لدى الاناث المصابات بفشل الزرع مقارنة بالاناث في مجموعات الزرع الناجحة.
Microbiological and Analytical Evaluation of Semi-Solid Formulations of Doxycycline Hyclate under Accelerated Stability Conditions
Authors: Aasi Ola , Alahmad Youssef Alahmad , Beesh Mustafa , Swed Amin
Published: February 2024

الدوكسيسكلين هايكلات هو مضاد حيوي واسع الطيف ينتمي لعائلة التتراسيكلينات، يستخدم بشكل واسع في معالجة العديد من الأمراض الالتهابيًة، ويعتبر الخط العلاجي الأوًل في تدبير الحالات المتوسطة إلى الشديدة من حب الشًباب. تم في هذا البحث صياغة أربع صيغ نصف صلبة للدوكسيسيكلين (F2,F1 كصيغ هلاميًة، F3,F4 كصيغ مرهميًة)، ثم عُرّضت الصيغ السابقة إلى شروط ثبات مسرًعة في حاضنات الثبات لمدة ثلاثة أشهر. تم تقييم الصيغ المحضرة باستخدام طرق ميكروبيولوجيًة وتحليلية وذلك خلال شهر وثلاثة أشهر.  استخدمت طريقة الانتشار على الآغار لتقييم الفعاليًة المضادة للجراثيم وذلك على نوعين من الجراثيم، العنقوديات المذهًبة والزائفة الزنجاريًة. بينما استخدم HPLC كطريقة تحليل كمية وكيفية لمقايسة الصيغ. أجريت مقارنة بين نتائج المقايسة الميكروبيولوجيًة والمقايسة التحليلية لتقييم الفعاليًة. أظهرت النتائج أن الصيغ المرهميّة F3,F4 أكثر ثباتاً من الصيغ الهلاميّة F1,F2، حيث بلغت النسبة المئوية للدوكسيسيكلين % 93و%91 للصيغة F3,F4 على التوالي وذلك عند الحفظ بدرجة حرارة الغرفة بعد شهر واحد. بينما بلغت النسبة%90 و65% للصيغ الهلاميّةF2,F1 عند الحفظ في نفس الشروط السابقة. أظهرت نتائج قياس الفعاليًة المضادة للجراثيم أن الصيغة المرهميًة F4 امتلكت أكبر قطر تثبيط جرثومي ويقدر بحوالي 31 ملم للعنقوديات المذهبة و26 ملم لـلزوائف الزنجارية وذلك بعد حفظ الصيغة لمدة ثلاثة أشهر عند درجة الحرارة 25ºم. وبالتالي حافظت الصيغ على فعاليتها على الرغم من التخرّب الكيميائي البنيوي للحاصل للدوكسيسيكلين. تعود هذه الفعالية إلى حقيقة أن نواتج التخرب لا تزال محافظة على الموقع البنيوي الفعًال والمسؤول عن إعطاء الفعاليًة المضادة للجراثيم.
Advancing (U-Th)/He Zircon Dating: Novel Approaches in Sample Preparation and Uncertainty Reduction
Authors: Hao Yuqi , Wang Ying , Zhang Zhuqi , Yu Jingxing , Wang Yizhou , Pang Jianzhang , Zhang Wanfeng , Zheng Dewen
Published: February 2024

The laser microprobe (U-Th)/He dating method is a new and efficient technique that utilizes an interoperable and integrated suite of instruments, including the excimer laser system, quadrupole helium mass spectrometer, and quadrupole inductively coupled plasma mass spectrometer. To demonstrate the applicability of this new method, we applied both the conventional and laser microprobe techniques to the Sri Lanka zircon (LGC-1). We obtained twenty-two (U-Th)/He ages on nine shards using the laser microprobe method, showing an average (U-Th)/He age of 471.1 ± 16.6 Ma (1σ). This result is generally consistent with the mean conventional age (484.1 ± 9.6 Ma) for twenty-two zircon fragments. Both are nearly equal to the age value (~476 Ma) predicted by the He diffusion model and the thermal history model of Sri Lanka highland. The variations in the laser microprobe-derived ages are most likely caused by the uncertainties in volume measurements, which is also common in other studies. We used the Mahalanobis distance technique to reduce the volume measurement bias by identifying and eliminating abnormal data.
Petrogenesis of the Early Paleozoic Dioritic–Granitic Magmatism in the Eastern North Qilian Orogen, NW China: Implications for Tethyan Tectonic Evolution
Authors: Xue Fei , Yang Fan , Ren Weidong , Santosh M. , Qian Zesheng , Huang Yin , Tan Zijian
Published: February 2024

The North Qilian Orogen witnessed the opening, subduction, and closure of the Proto-Tethys Qilian Ocean and the post-subduction of multiple exhumation events from Late Neoproterozoic to Early Paleozoic. The Early Paleozoic dioritic–granitic magmatic suites, prominently exposed in the eastern North Qilian Orogen, offer valuable insights into the evolution of the Proto-Tethys Ocean. However, their petrogenesis, magma source, and tectonic evolution remain controversial. Here, we investigate the Leigongshan, Zhigou, and Dalongcun intrusions and present geochronological, geochemical, and isotopic data, aiming to refine the comprehension of their timing and petrogenesis, which will contribute to understanding the tectonic evolution of the Proto-Tethys Ocean. Zircon U-Pb dating reveals mean ages of 471–427 Ma for these intrusions, consistent with compiled formation ages of dioritic–granitic intrusions in the eastern North Qilian Orogen, indicating close temporal links with the tectonic evolution of the Proto-Tethys Ocean during the Early Paleozoic. The studied magmatic rocks could be categorized into two major types: granitoids and diorites. The granitoids are majorly I-type granitoids that are generated through partial melting of the mafic lower crust and fractional crystallization at the middle-upper crust, with the involvement of mantle-derived materials. The diorites underwent limited crustal contamination and fractionation of hornblende, plagioclase, and some accessory minerals. They were derived mainly from the mixture of fertile mantle and reworked crustal components, with minor contributions from subduction-related slab fluids and sediment melts. In addition, all the studied Early Paleozoic dioritic–granitic intrusions (ca. 471–427 Ma) formed within subduction-related arc settings. Combined with the tectonic evolution of the Early Paleozoic Qilian orogenic system, we interpret these Cambrian to Silurian dioritic–granitic intrusions as tectonic responses to the subduction (ca. 520–460 Ma) and closure (~440 Ma) of the Proto-Tethys Ocean, whereas the Devonian Huangyanghe intrusion witnessed the final stage of extensional collapse of the Qilian orogenic system at ca. 400–360 Ma.
Plan de negocios para la venta de comida vegana para perros en Lima Moderna
Authors:   , Gutierrez Estrella Edwin Josue , Garcia Virrueta Julio Alonzo , Garcia Ucharima Flor De Maria , Vásquez López Janina , Farfán Colán Evelyn Karen
Published: February 2024

Nuestro proyecto se llama “Vegan dog food”, surge del análisis realizado que cada vez son más las personas que tienen obtienen una clase diferente de perros para que estos sean parte de la familia y no como una mascota por ende quieren brindarle tiempo, amor, atención y cuidados que los haga sentir a gusto, quisimos brindarle el protagonismo que ellos se merecen al ser parte del hogar que con solo batir su cola o escuchar sus ladridos nos brinda su felicidad y nos transmite esa paz que necesitamos en algún momento. Es por eso que decidimos y ofrecemos la venta de comida vegana para perros, con ingredientes libres de cualquier insumo que les pueda ocasionar algún mal y tengan esa felicidad que ellos se merecen. Para determinar la viabilidad del plan de negocio, se realizó una validación de mercado, donde se evidencio el perfil del comprador de la comida vegana con el objetivo determinar quiénes serían los principales compradores de las mismas y a quienes debíamos dirigir nuestra propuesta comercial.
Peningkatan Mutu Lulusan Melalui Jaringan Kemitraan Dengan Dunia Usaha Dan Dunia Industri di SMK PGRI 2 Ponorogo
Authors: Fata Asyrofi Yahya  , Maydatullaela
Published: February 2024

Vocational education in Indonesia is implemented through Vocational High Schools (SMK). SMKs are expected to be able to create graduates who are ready to work. However, in reality, the absorption of SMK graduates is still low. One way to overcome this is by building partnerships with DUDI. Building partnerships is very important to improve the quality of graduates of these educational institutions. Based on this, this study aims to examine the concept of partnership between schools and the business world and the industrial world in improving the quality of graduates. The research model used in this research is a qualitative method with data collection techniques through interviews, observation, and documentation. From the data analysis, it can be concluded that SMK PGRI 2 Ponorogo has carried out several stages in building partnerships. In addition, they also use a network model in the form of industrial classes and a collaboration model in the form of recruitment of students, internships, and PKL. As for the success in this partnership in the form of increasing academic aspects in the form of increasing the competence of students and winning championships in several competitions. While in the non-academic aspect in the form of increased curiosity of students, and the social aspects of students in the form of high compassion for others and high solidarity.
Challenging Error Correction in Recognised Byzantine Greek
Authors: Pavlopoulos John , Kougia Vasiliki , Arias Esteban Garces , Platanou Paraskevi , Shabalin Stepan , Liagkou Konstantina , Papadatos Emmanouil , Essler Holger , Camps Jean-Baptiste , Fischer Franz
Published: February 2024

Automatic correction of errors in Handwritten Text Recognition (HTR) output poses persistent challenges yet to be fully resolved. In this study, we introduce a shared task aimed at addressing this challenge, which attracted 271 submissions, yielding only a handful of successful approaches. This paper presents the datasets, the most effective methods, and an experimental analysis in error-correcting HTRed manuscripts and papyri in Byzantine Greek, the language that followed Classical and preceded Modern Greek. By using recognised and transcribed data from seven centuries, the two best-performing methods are compared, one based on a neural encoder-decoder architecture and the other based on linguistic knowledge. We show that the recognition error rate can be reduced by both, up to 2.5 points at the level of characters and up to 15 at the level of words, while also elucidating their respective strengths and weaknesses.
Variable-Density Velocity-Selective Magnetization Preparation for Non-Contrast-Enhanced Peripheral MR Angiography
Authors: Kim Minyoung , Hwang Inpyeong , Choi Seung Hong , Park Jaeseok , Shin Taehoon
Published: February 2024

Velocity-selective (VS) magnetization preparation has shown great promise for non-contrast-enhanced (NCE) magnetic resonance angiography (MRA) with the ability to generate positive angiographic contrast directly using a single 3D acquisition. However, existing VS-MRA methods have an issue of aliased saturation around a certain velocity, known as velocity field-of-view (vFOV), which can cause undesired signal loss in arteries. This study aimed to develop a new version of the VS preparation pulse sequence that overcomes the aliased saturation problem in conventional VS preparation. Utilizing the fact that an excitation profile is the Fourier transform of excitation k-space sampling, we sampled the k-space in a non-uniform fashion by scaling gradient pulses accordingly to have aliased excitation diffused over velocity. The variable density sampling function was numerically optimized to maximize the average of the velocity passband signal while minimizing its variance. The optimized variable density VS magnetization was validated through Bloch simulations and applied to peripheral NCE MRA in healthy subjects. The in-vivo experiments showed that the proposed variable density VS-MRA significantly lowered arterial signal loss observed in conventional VS-MRA, as evidenced by a higher arterial signal-to-noise ratio (58.50 ± 14.29 vs. 55.54 ± 12.32; p < 0.05) and improved artery-to-background contrast-to-noise ratio (22.75 ± 7.57 vs. 20.60 ± 6.51; p < 0.05).
Value of peripheral blood ratio in diagnosis and prognosis prediction of sinonasal squamous cell carcinoma Running title: Peripheral blood ratio in SNSCC
Authors: Wang Tian , Zhang Qi , Wang Li , Wang Jie , Song Xinmao
Published: February 2024

Sinonasal squamous cell carcinoma (SNSCC) usually presents at an advanced stage by the time of diagnosis, and there is still a lack of indicators to predict the prognosis of SNSCC patients. We aim to investigate whether the peripheral blood ratios might be good options for predicting the progress in patients with SNSCC. We performed a retrospective analysis on 198 patients with SNSCC and 63 healthy people as the normal control people (NCP) between January 2010 and December 2022. Systemic inflammatory response index (SIRI), platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR), and monocyte/lymphocyte ratio (LMR) were calculated. We compared the differences in these four peripheral blood ratios between the NCP and SNSCC patients and investigated the predictive value for the prognosis of SNSCC patients. SIRI, LMR, NLR, and PLR differed significantly between the NCP and SNSCC patients (P < 0.05). NLR (Area Under Curve, AUC: 0.813) had a higher diagnostic sensitivity than SIRI, LMR, and PLR for SNSCC patients. Multivariate cox-regression showed that high LMR was associated with poor prognosis. The values of NLR, SIRI, LMR, and PLR can be used as parameters for the auxiliary diagnosis and prognosis of SNSCC. In SNSCC patients, LMR is a sensitive factor in predicting OS and DMFS.
Identification of potential prognostic genes associated with the tumor microenvironment in chromophobe renal cell carcinoma based on weighted gene co-expression network analysis
Authors: Li Fangfang , Wang Siyuan , Hu Huiqing , Zhang Jie , Yu Helong , Zhong Fei
Published: February 2024

Background Chromophobe renal cell carcinoma (ChRCC) is the third prevalent type of renal cell carcinoma(RCC), making up 5% of all RCCs. The objective of this study was to define prognostic genes associated with the tumor microenvironment (TME) of ChRCC.
Methods Calculation of immune and stromal scores for ChRCC samples in the TCGA database using ESTIMATE algorithm. The differentially expressed genes (DEGs) were selected to construct co-expression modules by weighted gene co-expression network analysis(WGCNA), and hub modules were definited by calculating module-trait correlations to obtain TME-related DEGs. After that, we further analyzed the biological and molecular functions of these TME-related DEGs and evaluated their prognostic values. Finally, the online TIMER database was used to explore the infiltration of immune cells.
Results 468 DEGs were identified based on stromal scores and immune scores, of which 442 were upregulated genes and 26 were down-regulated genes. Subsequently, the 122 overlapping genes were predicted from WGCNA, and considered as TME-related genes. After analyzing by Molecular Complex Detection (MCODE) plugin from Cytoscape software, Functional enrichments analysis showed that TME-related genes in primary modules were associated with immune responses or inflammatory. Consequently, six TME-relate genes (ALOX5, FGR, GRASP, HLA-DQA1, HLA-DRB1, and ROBO4) were found to be correlated with overall survival of ChRCC and immune cells infiltration.
Conclusion We further analyzed the results by UALCAN databases, and combined with the IHC results of three specimens diagnosed with CHRCC, and finally found that the TME-relate ALOX5 may be a potential biomarker for the prognosis of ChRCC