bluuebunny/crossref_metadata_2025 huggingface dataset:
FigureS5 from Auranofin Protects Intestine against Radiation Injury by Modulating p53/p21 Pathway and Radiosensitizes Human Colon Tumor
Authors: Nag Dhrubajyoti , Bhanja Payel , Riha Randal , Sanchez-Guerrero Giselle , Kimler Bruce F. , Tsue Terance T. , Lominska Chris , Saha Subhrajit
Published: April 2023

Supplement FigureS5
Figure S3 from Auranofin Protects Intestine against Radiation Injury by Modulating p53/p21 Pathway and Radiosensitizes Human Colon Tumor
Authors: Nag Dhrubajyoti , Bhanja Payel , Riha Randal , Sanchez-Guerrero Giselle , Kimler Bruce F. , Tsue Terance T. , Lominska Chris , Saha Subhrajit
Published: April 2023

Supplement Figure S3
Supplemental data from CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies
Authors: Bacac Marina , Colombetti Sara , Herter Sylvia , Sam Johannes , Perro Mario , Chen Stanford , Bianchi Roberta , Richard Marine , Schoenle Anne , Nicolini Valeria , Diggelmann Sarah , Limani Florian , Schlenker Ramona , Hüsser Tamara , Richter Wolfgang , Bray-French Katharine , Hinton Heather , Giusti Anna Maria , Freimoser-Grundschober Anne , Lariviere Laurent , Neumann Christiane , Klein Christian , Umaña Pablo
Published: April 2023

Supplemental data details
9 Supplementary Figures from Krüppel-like Factor 4 Suppresses Serine/Threonine Kinase 33 Activation and Metastasis of Gastric Cancer through Reversing Epithelial–Mesenchymal Transition
Authors: Kong Fanyang , Sun Tao , Kong Xiangyu , Xie Dacheng , Li Zhaoshen , Xie Keping
Published: April 2023

9 Supplementary Figures: Supplementary Figure S1. Immunohitochemical analysis of STK33 in TMAs of gastric cancer tissue specimens with different differentiation grade. Supplementary Figure S2. Estimates of OS and DFS of gastric cancer patients from GSE66229 (N=300). Supplementary Figure S3. STK33 expression patterns in human gastric cancer tissues and cell lines. Supplementary Figure S4. Effect of altered STK33 expression on gastric cancer metastasis and EMT. Supplementary Figure S5. Effect of altered STK33 expression on gastric cancer growth in vitro and in vivo. Supplementary Figure S6. Identification of STK33 as a downstream target gene of KLF4. Supplementary Figure S7. KLF4 negatively regulated STK33-induced invasion and EMT. Supplementary Figure S8. Identification of transcriptional inhibition on STK33 expression by KLF4 in pancreatic cancer cells. Supplementary Figure S9. STK33 kinase inhibitor BRD-8899 failed to inhibit STK33-induced cell proliferation, migration and invasion in GC.
Table S1 from Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers
Authors: Anurag Meenakshi , Punturi Nindo , Hoog Jeremy , Bainbridge Matthew N. , Ellis Matthew J. , Haricharan Svasti
Published: April 2023

List of mutations identified in NeoAI discovery set
Table S6 from The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer
Authors: Barry Peter , Vatsiou Alexandra , Spiteri Inmaculada , Nichol Daniel , Cresswell George D. , Acar Ahmet , Trahearn Nicholas , Hrebien Sarah , Garcia-Murillas Isaac , Chkhaidze Kate , Ermini Luca , Huntingford Ian Said , Cottom Hannah , Zabaglo Lila , Koelble Konrad , Khalique Saira , Rusby Jennifer E. , Muscara Francesca , Dowsett Mitch , Maley Carlo C. , Natrajan Rachael , Yuan Yinyin , Schiavon Gaia , Turner Nicholas , Sottoriva Andrea
Published: April 2023

Whole-exome sequencing mutations cancer cell fractions used in Figure S2
Table S3 from The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer
Authors: Barry Peter , Vatsiou Alexandra , Spiteri Inmaculada , Nichol Daniel , Cresswell George D. , Acar Ahmet , Trahearn Nicholas , Hrebien Sarah , Garcia-Murillas Isaac , Chkhaidze Kate , Ermini Luca , Huntingford Ian Said , Cottom Hannah , Zabaglo Lila , Koelble Konrad , Khalique Saira , Rusby Jennifer E. , Muscara Francesca , Dowsett Mitch , Maley Carlo C. , Natrajan Rachael , Yuan Yinyin , Schiavon Gaia , Turner Nicholas , Sottoriva Andrea
Published: April 2023

Targeted sequencing mutations variant allele frequencies used to calculate cancer cell fractions
Supplementary Figure S4 from Salivary Gland Cancer Patient-Derived Xenografts Enable Characterization of Cancer Stem Cells and New Gene Events Associated with Tumor Progression
Authors: Keysar Stephen B. , Eagles Justin R. , Miller Bettina , Jackson Brian C. , Chowdhury Farshad N. , Reisinger Julie , Chimed Tugs-Saikhan , Le Phuong N. , Morton John J. , Somerset Hilary L. , Varella-Garcia Marileila , Tan Aik-Choon , Song John I. , Bowles Daniel W. , Reyland Mary E. , Jimeno Antonio
Published: April 2023

Fig. S4. Significantly enriched biological processes. Multiple biological pathways were differentially enriched in F1 vs. F0 and F2 vs. F0 comparisons. FDR adjusted p-values are represented by bubble color, while bubble size represents relative gene set sizes. The axes are not intrinsically meaningful, but simply serve to group similar GO terms more closely. (A) Biological processes enriched for downregulated genes in F1 vs. F0 comparisons. (B) Biological processes enriched for upregulated genes in F1 vs. F0 comparisons. (C) Biological processes enriched for downregulated genes in F2 vs. F0 comparisons. (D) Biological processes enriched for upregulated genes in F2 vs. F0 comparisons. the regulation of the immune response biological process was most significantly enriched for downregulated genes in both PDX generations when compared to F0 samples. Similarly, processes involving cytokine and leukocyte activity were also significantly downregulated, while epidermis development and keratinocyte-related processes were significantly enriched in PDX tumors.
Supplementary Figure 3 from The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer
Authors: Barry Peter , Vatsiou Alexandra , Spiteri Inmaculada , Nichol Daniel , Cresswell George D. , Acar Ahmet , Trahearn Nicholas , Hrebien Sarah , Garcia-Murillas Isaac , Chkhaidze Kate , Ermini Luca , Huntingford Ian Said , Cottom Hannah , Zabaglo Lila , Koelble Konrad , Khalique Saira , Rusby Jennifer E. , Muscara Francesca , Dowsett Mitch , Maley Carlo C. , Natrajan Rachael , Yuan Yinyin , Schiavon Gaia , Turner Nicholas , Sottoriva Andrea
Published: April 2023

Figure S3. Log-R-ratios and B-allele-frequency values.
Supplementary Figures from A Designer Cross-reactive DNA Immunotherapeutic Vaccine that Targets Multiple MAGE-A Family Members Simultaneously for Cancer Therapy
Authors: Duperret Elizabeth K. , Liu Shujing , Paik Megan , Trautz Aspen , Stoltz Regina , Liu Xiaoming , Ze Kan , Perales-Puchalt Alfredo , Reed Charles , Yan Jian , Xu Xiaowei , Weiner David B.
Published: April 2023

Supplementary Figure 1: Expression of human and mouse consensus MAGE-A plasmids in vitro. Supplementary Figure 2: Consensus mouse MAGE-A vaccine induces low CD4+ T cells in C57Bl/6 mice. Supplementary Figure 3: Consensus mouse MAGE-A vaccine induces immune responses to one dominant epitope. Supplementary Figure 4: MAGE-A vaccine induced memory T cell responses. Supplementary Figure 5: Evaluation of organ toxicity after MAGE-A immunization. Supplementary Figure 6: Expression of mouse MAGE-A in a panel of mouse tumor cell lines and in autochthonous melanomas. Supplementary Figure 7: Immune responses in spleen and tumor of autochthonous tumor bearing mice. Supplementary Figure 8: Impact of MAGE-A vaccine in YUMM1.7 subcutaneous tumor model.
Supplementary Table S2 from Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-Risk MYCN-Not-Amplified Human Neuroblastoma
Authors: Wei Jun S. , Kuznetsov Igor B. , Zhang Shile , Song Young K. , Asgharzadeh Shahab , Sindiri Sivasish , Wen Xinyu , Patidar Rajesh , Najaraj Sushma , Walton Ashley , Guidry Auvil Jaime M. , Gerhard Daniela S. , Yuksel Aysen , Catchpoole Daniel , Hewitt Stephen M. , Sondel Paul M. , Seeger Robert , Maris John M. , Khan Javed
Published: April 2023

Supplementary Table S2
Supplementary Table S1 from Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-Risk MYCN-Not-Amplified Human Neuroblastoma
Authors: Wei Jun S. , Kuznetsov Igor B. , Zhang Shile , Song Young K. , Asgharzadeh Shahab , Sindiri Sivasish , Wen Xinyu , Patidar Rajesh , Najaraj Sushma , Walton Ashley , Guidry Auvil Jaime M. , Gerhard Daniela S. , Yuksel Aysen , Catchpoole Daniel , Hewitt Stephen M. , Sondel Paul M. , Seeger Robert , Maris John M. , Khan Javed
Published: April 2023

Supplementary Table S1
Supplementary Figures from Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-Risk MYCN-Not-Amplified Human Neuroblastoma
Authors: Wei Jun S. , Kuznetsov Igor B. , Zhang Shile , Song Young K. , Asgharzadeh Shahab , Sindiri Sivasish , Wen Xinyu , Patidar Rajesh , Najaraj Sushma , Walton Ashley , Auvil Jaime M. Guidry , Gerhard Daniela S. , Yuksel Aysen , Catchpoole Daniel , Hewitt Stephen M. , Sondel Paul M. , Seeger Robert , Maris John M. , Khan Javed
Published: April 2023

Supplementary Figures S1-S9
Supplementary Figure 2 from Inhibition of EphB4–Ephrin-B2 Signaling Enhances Response to Cetuximab–Radiation Therapy in Head and Neck Cancers
Authors: Bhatia Shilpa , Sharma Jaspreet , Bukkapatnam Sanjana , Oweida Ayman , Lennon Shelby , Phan Andy , Milner Dallin , Uyanga Nomin , Jimeno Antonio , Raben David , Somerset Hilary , Heasley Lynn , Karam Sana D.
Published: April 2023

Blockade of EphB4-ephrin-B2 enhances response to EGFR inhibitor (cetuximab) and RT resulting in significant delay in tumor growth and enhanced survival in HNSCC PDX models. Tumor growth volumes are displayed in CUHN013 (A) and CUHN004 (B) tumors including cisplatin-RT treated groups in the absence and presence of sEphB4-HSA. Cisplatin-RT treated groups did not show any significant changes in tumor growth in the absence and presence of sEphB4-HSA in CUHN013 tumors. Survival graphs are shown for CUHN013 (C) and CUHN004 (D) tumors.
Supplementary Figure 1 from A Pilot Study of Liposomal Doxorubicin Combined with Bevacizumab followed by Bevacizumab Monotherapy in Patients with Advanced Kaposi Sarcoma
Authors: Ramaswami Ramya , Uldrick Thomas S. , Polizzotto Mark N. , Wyvill Kathleen M. , Goncalves Priscila , Widell Anaida , Lurain Kathryn , Steinberg Seth M. , Figg William Douglas , Tosato Giovanna , Whitby Denise , Yarchoan Robert
Published: April 2023

Diagram to represent the treatment course and responses among patients treated within the study. *Patient had progressive disease of cutaneous KS but continued with treatment due to improvement in symptomatic pulmonary KS.
Figure S3 from Genetic Polymorphisms Predisposing the Interleukin 6–Induced APOBEC3B-UNG Imbalance Increase HCC Risk via Promoting the Generation of APOBEC-Signature HBV Mutations
Authors: Liu Wenbin , Wu Jianfeng , Yang Fan , Ma Longteng , Ni Chong , Hou Xiaomei , Wang Ling , Xu Aijing , Song Jiahui , Deng Yang , Xian Linfeng , Li Zixiong , Wang Shuo , Chen Xi , Yin Jianhua , Han Xue , Li Chengzhong , Zhao Jun , Cao Guangwen
Published: April 2023

Study design for the stratification analyses
Figure S2 from Genetic Polymorphisms Predisposing the Interleukin 6–Induced APOBEC3B-UNG Imbalance Increase HCC Risk via Promoting the Generation of APOBEC-Signature HBV Mutations
Authors: Liu Wenbin , Wu Jianfeng , Yang Fan , Ma Longteng , Ni Chong , Hou Xiaomei , Wang Ling , Xu Aijing , Song Jiahui , Deng Yang , Xian Linfeng , Li Zixiong , Wang Shuo , Chen Xi , Yin Jianhua , Han Xue , Li Chengzhong , Zhao Jun , Cao Guangwen
Published: April 2023

Schematic plot of genetic polymorphisms at the transcriptional regulatory regions of APOBEC3 and UNG
Figure S6 from Localized Treatment with Oncolytic Adenovirus Delta-24-RGDOX Induces Systemic Immunity against Disseminated Subcutaneous and Intracranial Melanomas
Authors: Jiang Hong , Shin Dong Ho , Nguyen Teresa T. , Fueyo Juan , Fan Xuejun , Henry Verlene , Carrillo Caroline C. , Yi Yanhua , Alonso Marta M. , Collier Tiara L. , Yuan Ying , Lang Frederick F. , Gomez-Manzano Candelaria
Published: April 2023

Exhausted T cells and regulatory T cells in peripheral blood and inguinal lymph nodes. Tumors were implanted and treated as depicted in Fig. 2A. Three days after the last viral injection, lymphocytes from blood or inguinal lymph nodes (4 to 5 mice/group) were analyzed with flow cytometry for T cell exhaustion (PD-1+ TIM3+, A) and regulatory T cells (CD4+ CD25+ FR4+, B). D24-RGDOX: Delta-24-RGDOX.
Supplementary Table from The Indenoisoquinoline TOP1 Inhibitors Selectively Target Homologous Recombination-Deficient and Schlafen 11-Positive Cancer Cells and Synergize with Olaparib
Authors: Marzi Laetitia , Szabova Ludmila , Gordon Melanie , Weaver Ohler Zoe , Sharan Shyam K. , Beshiri Michael L. , Etemadi Moudjib , Murai Junko , Kelly Kathleen , Pommier Yves
Published: April 2023

LMP400 activity values for all NCI-60 cell lines
Supplementary table 2 from Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning
Authors: Yokoyama Seiya , Hamada Taiji , Higashi Michiyo , Matsuo Kei , Maemura Kosei , Kurahara Hiroshi , Horinouchi Michiko , Hiraki Tsubasa , Sugimoto Tomoyuki , Akahane Toshiaki , Yonezawa Suguru , Kornmann Marko , Batra Surinder K. , Hollingsworth Michael A. , Tanimoto Akihide
Published: April 2023

LOOCV test and clinicopathological data
Supplementary figure 3 from Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning
Authors: Yokoyama Seiya , Hamada Taiji , Higashi Michiyo , Matsuo Kei , Maemura Kosei , Kurahara Hiroshi , Horinouchi Michiko , Hiraki Tsubasa , Sugimoto Tomoyuki , Akahane Toshiaki , Yonezawa Suguru , Kornmann Marko , Batra Surinder K. , Hollingsworth Michael A. , Tanimoto Akihide
Published: April 2023

Cox proportional hazard regression analysis on a comparison between Cluster 1 and other clusters as selected by cluster analysis of the methylation status of mucin genes MUC1, MUC2, and MUC4 in non-neoplastic regions (A) and neoplastic regions (B). Red solid line: Cluster 1, black dashed line: other clusters.
Supplementary figure 1 from Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning
Authors: Yokoyama Seiya , Hamada Taiji , Higashi Michiyo , Matsuo Kei , Maemura Kosei , Kurahara Hiroshi , Horinouchi Michiko , Hiraki Tsubasa , Sugimoto Tomoyuki , Akahane Toshiaki , Yonezawa Suguru , Kornmann Marko , Batra Surinder K. , Hollingsworth Michael A. , Tanimoto Akihide
Published: April 2023

Cox proportional hazard regression analysis on a comparison between Cluster 1 and Cluster 2 selected by cluster analysis of mRNA expression levels of MUC1, MUC2, and MUC4 in non-neoplastic regions (A) and neoplastic regions (B). Red solid line: Cluster 1, black dashed line: Cluster 2.
Supplementary Table 1 from A Novel HER3-Targeting Antibody–Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization
Authors: Hashimoto Yuuri , Koyama Kumiko , Kamai Yasuki , Hirotani Kenji , Ogitani Yusuke , Zembutsu Akiko , Abe Manabu , Kaneda Yuki , Maeda Naoyuki , Shiose Yoshinobu , Iguchi Takuma , Ishizaka Tomomichi , Karibe Tsuyoshi , Hayakawa Ichiro , Morita Koji , Nakada Takashi , Nomura Taisei , Wakita Kenichi , Kagari Takashi , Abe Yuki , Murakami Masato , Ueno Suguru , Agatsuma Toshinori
Published: April 2023

Summary of repeated dose toxicity studies in rats and monkeys
Supplementary Materials and Methods from A Novel HER3-Targeting Antibody–Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization
Authors: Hashimoto Yuuri , Koyama Kumiko , Kamai Yasuki , Hirotani Kenji , Ogitani Yusuke , Zembutsu Akiko , Abe Manabu , Kaneda Yuki , Maeda Naoyuki , Shiose Yoshinobu , Iguchi Takuma , Ishizaka Tomomichi , Karibe Tsuyoshi , Hayakawa Ichiro , Morita Koji , Nakada Takashi , Nomura Taisei , Wakita Kenichi , Kagari Takashi , Abe Yuki , Murakami Masato , Ueno Suguru , Agatsuma Toshinori
Published: April 2023

Supplementary materials and methods for xenograft studies and IHC
Supplementary Figure 3 from A Novel HER3-Targeting Antibody–Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization
Authors: Hashimoto Yuuri , Koyama Kumiko , Kamai Yasuki , Hirotani Kenji , Ogitani Yusuke , Zembutsu Akiko , Abe Manabu , Kaneda Yuki , Maeda Naoyuki , Shiose Yoshinobu , Iguchi Takuma , Ishizaka Tomomichi , Karibe Tsuyoshi , Hayakawa Ichiro , Morita Koji , Nakada Takashi , Nomura Taisei , Wakita Kenichi , Kagari Takashi , Abe Yuki , Murakami Masato , Ueno Suguru , Agatsuma Toshinori
Published: April 2023

Antitumor activity of U3-1402 in HER3-positive HCC1569 and MDA-MB-453 xenograft models
Supplementary Figure 2 from Combination Paclitaxel and Palbociclib: Results of a Phase I Trial in Advanced Breast Cancer
Authors: Clark Amy S. , McAndrew Nicholas P. , Troxel Andrea , Feldman Michael , Lal Priti , Rosen Mark , Burrell Jessica , Redlinger Colleen , Gallagher Maryann , Bradbury Angela R. , Domchek Susan M. , Fox Kevin R. , O'Dwyer Peter J. , DeMichele Angela M.
Published: April 2023

KM Curves
Table S2 from The Hsp27-Mediated IkBα-NFκB Signaling Axis Promotes Radiation-Induced Lung Fibrosis
Authors: Kim Jee-Youn , Jeon Seulgi , Yoo Young Jo , Jin Hee , Won Hee Yeon , Yoon Kyeonghee , Hwang Eun Sook , Lee Yoon-Jin , Na Younghwa , Cho Jaeho , Lee Yun-Sil
Published: April 2023

The parameter description using the flexiVentTM system measurements
Figure S4 from High-throughput Screening of Human Tumor Antigen–specific CD4 T Cells, Including Neoantigen-reactive T Cells
Authors: Costa-Nunes Carla , Cachot Amélie , Bobisse Sara , Arnaud Marion , Genolet Raphael , Baumgaertner Petra , Speiser Daniel E. , Sousa Alves Pedro M. , Sandoval Federico , Adotévi Olivier , Reith Walter , Protti Maria Pia , Coukos George , Harari Alexandre , Romero Pedro , Jandus Camilla
Published: April 2023

Supplementary Figure 4
Figure S1 from High-throughput Screening of Human Tumor Antigen–specific CD4 T Cells, Including Neoantigen-reactive T Cells
Authors: Costa-Nunes Carla , Cachot Amélie , Bobisse Sara , Arnaud Marion , Genolet Raphael , Baumgaertner Petra , Speiser Daniel E. , Sousa Alves Pedro M. , Sandoval Federico , Adotévi Olivier , Reith Walter , Protti Maria Pia , Coukos George , Harari Alexandre , Romero Pedro , Jandus Camilla
Published: April 2023

Supplementary Figure 1
Supplementary Data from Prognostic Implications of PD-L1 Expression in Breast Cancer: Systematic Review and Meta-analysis of Immunohistochemistry and Pooled Analysis of Transcriptomic Data
Authors: Matikas Alexios , Zerdes Ioannis , Lövrot John , Richard François , Sotiriou Christos , Bergh Jonas , Valachis Antonios , Foukakis Theodoros
Published: April 2023

Supplementary Data
Supplementary Data from Vitamin D Modifies the Incidence of Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation Depending on the Vitamin D Receptor (VDR) Polymorphisms
Authors: Carrillo-Cruz Estrella , García-Lozano José R. , Márquez-Malaver Francisco J. , Sánchez-Guijo Fermín M. , Montero Cuadrado Isabel , Ferra i Coll Christelle , Valcárcel David , López-Godino Oriana , Cuesta Marian , Parody Rocío , López-Corral Lucía , Alcoceba Miguel , Caballero-Velázquez Teresa , Rodríguez-Gil Alfonso , Bejarano-García José A. , Ramos Teresa Lopes , Pérez-Simón José A.
Published: April 2023

Supplementary table 2. VDR genotype and haplotype frequencies.
Supplementary Data from Vitamin D Modifies the Incidence of Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation Depending on the Vitamin D Receptor (VDR) Polymorphisms
Authors: Carrillo-Cruz Estrella , García-Lozano José R. , Márquez-Malaver Francisco J. , Sánchez-Guijo Fermín M. , Montero Cuadrado Isabel , Ferra i Coll Christelle , Valcárcel David , López-Godino Oriana , Cuesta Marian , Parody Rocío , López-Corral Lucía , Alcoceba Miguel , Caballero-Velázquez Teresa , Rodríguez-Gil Alfonso , Bejarano-García José A. , Ramos Teresa Lopes , Pérez-Simón José A.
Published: April 2023

Supplementary table 5. Impact of donor VDR polymorphisms on the incidence of overall and moderate to severe chronic GVHD.
Supplementary Data 3 from Vitamin D Modifies the Incidence of Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation Depending on the Vitamin D Receptor (VDR) Polymorphisms
Authors: Carrillo-Cruz Estrella , García-Lozano José R. , Márquez-Malaver Francisco J. , Sánchez-Guijo Fermín M. , Montero Cuadrado Isabel , Ferra i Coll Christelle , Valcárcel David , López-Godino Oriana , Cuesta Marian , Parody Rocío , López-Corral Lucía , Alcoceba Miguel , Caballero-Velázquez Teresa , Rodríguez-Gil Alfonso , Bejarano-García José A. , Ramos Teresa Lopes , Pérez-Simón José A.
Published: April 2023

Linkage disequilibrium of patients VDR polymorphisms.
Supplementary Figures from TP53 Pathway Alterations Drive Radioresistance in Diffuse Intrinsic Pontine Gliomas (DIPG)
Authors: Werbrouck Coralie , Evangelista Cláudia C.S. , Lobón-Iglesias María-Jesús , Barret Emilie , Le Teuff Gwénaël , Merlevede Jane , Brusini Romain , Kergrohen Thomas , Mondini Michele , Bolle Stéphanie , Varlet Pascale , Beccaria Kevin , Boddaert Nathalie , Puget Stéphanie , Grill Jacques , Debily Marie-Anne , Castel David
Published: April 2023

All supplementary figures in one PDF
Supplementary Data from Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma
Authors: Prukova Dana , Andera Ladislav , Nahacka Zuzana , Karolova Jana , Svaton Michael , Klanova Magdalena , Havranek Ondrej , Soukup Jan , Svobodova Karla , Zemanova Zuzana , Tuskova Diana , Pokorna Eva , Helman Karel , Forsterova Kristina , Pacheco-Blanco Mariana , Vockova Petra , Berkova Adela , Fronkova Eva , Trneny Marek , Klener Pavel
Published: April 2023

Supplemental Figure 1. Next-generation sequencing of PDXs and primary MCL cells Supplemental Figure 2. IHC analysis of primary MCL samples and murine xenografts Supplemental Figure 3. Array comparative genomic hybridization of 24 primary MCL samples Supplemental Figure 4. Sensitivity of HBL2 and MAVER-1 cells resistant to venetoclax to BCL-XL inhibitors WEHI-539 and A1155463 Supplemental Table 1. Complete list of protein coding variants Supplemental Table 2. FISH analyses of the established murine PDXs of MCL Supplemental Table 3. Baseline characteristics of patients Supplemental Table 4. IHC analysis of MCL samples and xenografts Supplemental Table 5. Tumor and spleen weights at the end of in vivo experiments
Supplementary Data from Phosphoproteomic and Kinomic Signature of Clinically Aggressive Grade I (1.5) Meningiomas Reveals RB1 Signaling as a Novel Mediator and Biomarker
Authors: Parada Carolina A. , Osbun Joshua W. , Busald Tina , Karasozen Yigit , Kaur Sumanpreet , Shi Min , Barber Jason , Adidharma Widya , Cimino Patrick J. , Pan Catherine , Gonzalez-Cuyar Luis F. , Rostomily Robert , Born Donald E. , Zhang Jing , Ferreira Manuel
Published: April 2023

Figure S5
Supplementary Data from Phosphoproteomic and Kinomic Signature of Clinically Aggressive Grade I (1.5) Meningiomas Reveals RB1 Signaling as a Novel Mediator and Biomarker
Authors: Parada Carolina A. , Osbun Joshua W. , Busald Tina , Karasozen Yigit , Kaur Sumanpreet , Shi Min , Barber Jason , Adidharma Widya , Cimino Patrick J. , Pan Catherine , Gonzalez-Cuyar Luis F. , Rostomily Robert , Born Donald E. , Zhang Jing , Ferreira Manuel
Published: April 2023

Table S3
Supplementary Data from Phosphoproteomic and Kinomic Signature of Clinically Aggressive Grade I (1.5) Meningiomas Reveals RB1 Signaling as a Novel Mediator and Biomarker
Authors: Parada Carolina A. , Osbun Joshua W. , Busald Tina , Karasozen Yigit , Kaur Sumanpreet , Shi Min , Barber Jason , Adidharma Widya , Cimino Patrick J. , Pan Catherine , Gonzalez-Cuyar Luis F. , Rostomily Robert , Born Donald E. , Zhang Jing , Ferreira Manuel
Published: April 2023

Table S6
Supplementary Data from Phosphoproteomic and Kinomic Signature of Clinically Aggressive Grade I (1.5) Meningiomas Reveals RB1 Signaling as a Novel Mediator and Biomarker
Authors: Parada Carolina A. , Osbun Joshua W. , Busald Tina , Karasozen Yigit , Kaur Sumanpreet , Shi Min , Barber Jason , Adidharma Widya , Cimino Patrick J. , Pan Catherine , Gonzalez-Cuyar Luis F. , Rostomily Robert , Born Donald E. , Zhang Jing , Ferreira Manuel
Published: April 2023

Table S7
Supplementary Table S2 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Authors: Field Matthew G. , Kuznetsov Jeffim N. , Bussies Parker L. , Cai Louie Z. , Alawa Karam A. , Decatur Christina L. , Kurtenbach Stefan , Harbour J. William
Published: April 2023

TCGA_Methyl_DMP: All significantly methylated probes (FDR < 0.05) in Class 2 uveal melanomas compared to Class 1 uveal melanomas from the 80 TCGA cases. JWH_Methyl_DMP: All significantly methylated probes (p < 0.05) in Class 2 uveal melanomas compared to Class 1 uveal melanomas from 12 cases of the senior author (JWH). TCGA_D12_PC1_PC2_Methyl: The 67,261 probes shared between the top 20% most variable methylated probes from the TCGA and JWH datasets used in the principal component analyses. The percentage contribution to PC1 and PC2 are displayed for all probes. TCGA_D12_Probes_Top5000PC1: The 204 probes shared between the TCGA and JWH datasets out of the Top 5000 shared most variable methylated probes contributing to PC1 in the principal component analyses.
Supplementary materials from Tumor-associated Macrophages as Prognostic and Predictive Biomarkers for Postoperative Adjuvant Chemotherapy in Patients with Stage II Colon Cancer
Authors: Feng Qingyang , Chang Wenju , Mao Yihao , He Guodong , Zheng Peng , Tang Wentao , Wei Ye , Ren Li , Zhu Dexiang , Ji Meiling , Tu Yongjiu , Qin Xinyu , Xu Jianmin
Published: April 2023

All supplementary materials
Supplementary Figure S1 from BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
Authors: Field Matthew G. , Kuznetsov Jeffim N. , Bussies Parker L. , Cai Louie Z. , Alawa Karam A. , Decatur Christina L. , Kurtenbach Stefan , Harbour J. William
Published: April 2023

BAP1 knockdown alters the epigenomic profile in uveal melanoma (UM) cells. (A) Western blot of tetracycline-inducible 92.1 and Mel202 shBAP1 UM cells without (-) and with (+) induction by doxycycline. (B) Multidimensional scaling (MDS) plot of the 1000 most variably methylated probes in the BAP1KD cell experiment, comparing the tetracycline-induced BAP1KD cells (BAP1KD, red) to the un-induced BAP1 control cells (BAP1WT, green). (C) Hierarchical clustering dendrogram, using all methylation probes, plotting the induced (BAP1KD) and uninduced (BAP1WT) 92.1 and Mel202 biological replicates.
Supplementary Data from Phase I and Pharmacology Study of Ropidoxuridine (IPdR) as Prodrug for Iododeoxyuridine-Mediated Tumor Radiosensitization in Advanced GI Cancer Undergoing Radiation
Authors: Kinsella Timothy , Safran Howard , Wiersma Susan , DiPetrillo Thomas , Schumacher Andrew , Rosati Kayla , Vatkevich John , Anderson Lawrence W. , Hill Kimberly D. , Kunos Charles , Collins Jerry M.
Published: April 2023

Figure S1: Supplementary pharmacokinetic analyses
Supplementary Data from LRP6 Ectodomain Prevents SDF-1/CXCR4-Induced Breast Cancer Metastasis to Lung
Authors: Zhang Jiankang , Chen Jinxiao , Wo Da , Yan Hongwei , Liu Peng , Ma En , Li Limei , Zheng Liang , Chen Daxin , Yu Zuoren , Liang Chunli , Peng Jun , Ren Dan-ni , Zhu Weidong
Published: April 2023

Supplementary Figures, Figure legends and Tables
Figure S2 from Comprehensive Next-Generation Sequencing Unambiguously Distinguishes Separate Primary Lung Carcinomas From Intrapulmonary Metastases: Comparison with Standard Histopathologic Approach
Authors: Chang Jason C. , Alex Deepu , Bott Matthew , Tan Kay See , Seshan Venkatraman , Golden Andrew , Sauter Jennifer L. , Buonocore Darren J. , Vanderbilt Chad M. , Gupta Sounak , Desmeules Patrice , Bodd Francis M. , Riely Gregory J. , Rusch Valerie W. , Jones David R. , Arcila Maria E. , Travis William D. , Ladanyi Marc , Rekhtman Natasha
Published: April 2023

Supplemental Figure 2
Figure S2 from The CHK1 Inhibitor Prexasertib Exhibits Monotherapy Activity in High-Grade Serous Ovarian Cancer Models and Sensitizes to PARP Inhibition
Authors: Parmar Kalindi , Kochupurakkal Bose S. , Lazaro Jean-Bernard , Wang Zhigang C. , Palakurthi Sangeetha , Kirschmeier Paul T. , Yang Chunyu , Sambel Larissa A. , Färkkilä Anniina , Reznichenko Elizaveta , Reavis Hunter D. , Dunn Connor E. , Zou Lee , Do Khanh T. , Konstantinopoulos Panagiotis A. , Matulonis Ursula A. , Liu Joyce F. , D'Andrea Alan D. , Shapiro Geoffrey I.
Published: April 2023

Body weights of HGSOC tumor-bearing mice treated with prexasertib or prexasertib/olaparib
Supplemental Tables 1-3 from B7-H3 Expression in Merkel Cell Carcinoma–Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density
Authors: Aung Phyu P. , Parra Edwin Roger , Barua Souptik , Sui Dawen , Ning Jing , Mino Barbara , Ledesma Debora Alejandra , Curry Jonathan L. , Nagarajan Priyadharsini , Torres-Cabala Carlos A. , Efstathiou Eleni , Hoang Anh G. , Wong Michael K. , Wargo Jennifer A. , Lazar Alexander J. , Rao Arvind , Prieto Victor G. , Wistuba Ignacio , Tetzlaff Michael T.
Published: April 2023

Supplemental Table 1. Summary of the clinical and histopathologic characteristics of Merkel cell carcinoma patients. Supplemental Table 2. Summary of antibodies used in this study. Supplemental Table 3. Correlation between tumor associated immune infiltrate and co-localized expression of CD31 and B7-H3 in Primary MCCs.
Supplementary Figures from NKT Cells Coexpressing a GD2-Specific Chimeric Antigen Receptor and IL15 Show Enhanced In Vivo Persistence and Antitumor Activity against Neuroblastoma
Authors: Xu Xin , Huang Wei , Heczey Andras , Liu Daofeng , Guo Linjie , Wood Michael , Jin Jingling , Courtney Amy N. , Liu Bin , Di Pierro Erica J. , Hicks John , Barragan Gabriel A. , Ngai Ho , Chen Yuhui , Savoldo Barbara , Dotti Gianpietro , Metelitsa Leonid S.
Published: April 2023

All Supplementary Figures with legends
Supplementary Data from A Novel Mechanism Driving Poor-Prognosis Prostate Cancer: Overexpression of the DNA Repair Gene, Ribonucleotide Reductase Small Subunit M2 (RRM2)
Authors: Mazzu Ying Z. , Armenia Joshua , Chakraborty Goutam , Yoshikawa Yuki , Coggins Si'Ana A. , Nandakumar Subhiksha , Gerke Travis A. , Pomerantz Mark M. , Qiu Xintao , Zhao Huiyong , Atiq Mohammad , Khan Nabeela , Komura Kazumasa , Lee Gwo-Shu Mary , Fine Samson W. , Bell Connor , O'Connor Edward , Long Henry W. , Freedman Matthew L. , Kim Baek , Kantoff Philip W.
Published: April 2023

Supplemental tables, figures, and figure captions.
Figure S5 from A Novel Mechanism Driving Poor-Prognosis Prostate Cancer: Overexpression of the DNA Repair Gene, Ribonucleotide Reductase Small Subunit M2 (RRM2)
Authors: Mazzu Ying Z. , Armenia Joshua , Chakraborty Goutam , Yoshikawa Yuki , Coggins Si'Ana A. , Nandakumar Subhiksha , Gerke Travis A. , Pomerantz Mark M. , Qiu Xintao , Zhao Huiyong , Atiq Mohammad , Khan Nabeela , Komura Kazumasa , Lee Gwo-Shu Mary , Fine Samson W. , Bell Connor , O'Connor Edward , Long Henry W. , Freedman Matthew L. , Kim Baek , Kantoff Philip W.
Published: April 2023

Figure S5
Supplementary Data from Mutational Analysis of 472 Urothelial Carcinoma Across Grades and Anatomic Sites
Authors: Nassar Amin H. , Umeton Renato , Kim Jaegil , Lundgren Kevin , Harshman Lauren , Van Allen Eliezer M. , Preston Mark , Dong Fei , Bellmunt Joaquim , Mouw Kent W. , Choueiri Toni K. , Sonpavde Guru , Kwiatkowski David J.
Published: April 2023

Master table presenting multiple data sets for this cohort of 472 patients.
Table S5 from Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma
Authors: Vaubel Rachael A. , Tian Shulan , Remonde Dioval , Schroeder Mark A. , Mladek Ann C. , Kitange Gaspar J. , Caron Alissa , Kollmeyer Thomas M. , Grove Rebecca , Peng Sen , Carlson Brett L. , Ma Daniel J. , Sarkar Gobinda , Evers Lisa , Decker Paul A. , Yan Huihuang , Dhruv Harshil D. , Berens Michael E. , Wang Qianghu , Marin Bianca M. , Klee Eric W. , Califano Andrea , LaChance Daniel H. , Eckel-Passow Jeanette E. , Verhaak Roel G. , Sulman Erik P. , Burns Terry C. , Meyer Fredrick B. , O'Neill Brian P. , Tran Nhan L. , Giannini Caterina , Jenkins Robert B. , Parney Ian F. , Sarkaria Jann N.
Published: April 2023

Genetics of recurrent PDX
Supplementary Data from Mutational Analysis of 472 Urothelial Carcinoma Across Grades and Anatomic Sites
Authors: Nassar Amin H. , Umeton Renato , Kim Jaegil , Lundgren Kevin , Harshman Lauren , Van Allen Eliezer M. , Preston Mark , Dong Fei , Bellmunt Joaquim , Mouw Kent W. , Choueiri Toni K. , Sonpavde Guru , Kwiatkowski David J.
Published: April 2023

Supplementary Material Legends
Supplementary Figure S1 from Tumor-Associated Fibroblasts Promote HER2-Targeted Therapy Resistance through FGFR2 Activation
Authors: Fernández-Nogueira Patricia , Mancino Mario , Fuster Gemma , López-Plana Anna , Jauregui Patricia , Almendro Vanesa , Enreig Estel , Menéndez Silvia , Rojo Federico , Noguera-Castells Aleix , Bill Anke , Gaither L. Alex , Serrano Laia , Recalde-Percaz Leire , Moragas Núria , Alonso Raul , Ametller Elisabet , Rovira Ana , Lluch Ana , Albanell Joan , Gascon Pere , Bragado Paloma
Published: April 2023

Development of the anti-HER2 targeted therapies resistant breast cancer cell lines panel and immortalized fibroblast cell lines
Supplementary Table 4 from Liver- and Microbiome-derived Bile Acids Accumulate in Human Breast Tumors and Inhibit Growth and Improve Patient Survival
Authors: Tang Wei , Putluri Vasanta , Ambati Chandrashekar R. , Dorsey Tiffany H. , Putluri Nagireddy , Ambs Stefan
Published: April 2023

Altered gene expression in the Steroid Hormone Biosynthesis pathway in deoxycholate-treated T47D cells
Supplementary Table 3 from Liver- and Microbiome-derived Bile Acids Accumulate in Human Breast Tumors and Inhibit Growth and Improve Patient Survival
Authors: Tang Wei , Putluri Vasanta , Ambati Chandrashekar R. , Dorsey Tiffany H. , Putluri Nagireddy , Ambs Stefan
Published: April 2023

Altered gene expression in the Steroid Biosynthesis pathway in deoxycholate-treated T47D cells
Supplementary Figures from Liver- and Microbiome-derived Bile Acids Accumulate in Human Breast Tumors and Inhibit Growth and Improve Patient Survival
Authors: Tang Wei , Putluri Vasanta , Ambati Chandrashekar R. , Dorsey Tiffany H. , Putluri Nagireddy , Ambs Stefan
Published: April 2023

Supplementary Figure 1. Relative abundance of glycochenodeoxycholate (GCDC) in human breast tumors and adjacent non-cancerous tissues. Supplementary Figure 2. Association of fatty acid metabolism-related metabolites with breast cancer survival. Supplementary Figure 3. Correlation matrix for bile acids in the Tang et al. breast cancer dataset ("Duke cohort") and association of glycochenodeoxycholate (GCDC) with tumor subtype and proliferation. Supplementary Figure 4. Inverse association between bile acid levels and the tumor proliferation score. Supplementary Figure 5. Tissue glycochenodeoxycholate (GCDC) levels in tumor-adjacent non-cancerous tissue (n = 65) do not associate with the tissue proliferation score. Supplementary Figure 6. Proteomics identifies the Complement & Coagulation pathway as being activated in breast tumors with high glycochenodeoxycholate (GCDC). Supplementary Figure 7. Up-regulated proteins of the Complement & Coagulation Cascade in glycochenodeoxycholate (GCDC)-high tumors. Supplementary Figure 8. TGR5 and OATP1B1/3 antagonists attenuate the anti-proliferative effect of deoxycholate (DC) in T47D cells. Supplementary Figure 9. Up-regulated genes in the Steroid Biosynthesis pathway in deoxycholate-treated T47D cells. Supplementary Figure 10. Differentially expressed genes in the Steroid Hormone Biosynthesis pathway in deoxycholate-treated T47D cells.
Supplementary Data from A Validation Study on IDO Immune Biomarkers for Survival Prediction in Non–Small Cell Lung Cancer: Radiation Dose Fractionation Effect in Early-Stage Disease
Authors: Wang Weili , Huang Lei , Jin Jian-Yue , Pi Wenhu , Ellsworth Susannah G. , Jolly Shruti , Mellor Andrew L. , Machtay Mitchell , Kong Feng-Ming (Spring)
Published: April 2023

Table S1 and Figure S1
Supplementary Figure 2 from SMAD4 Loss in Colorectal Cancer Patients Correlates with Recurrence, Loss of Immune Infiltrate, and Chemoresistance
Authors: Wasserman Isaac , Lee Lik Hang , Ogino Shuji , Marco Michael R. , Wu Chao , Chen Xi , Datta Jashodeep , Sadot Eran , Szeglin Bryan , Guillem Jose G. , Paty Philip B. , Weiser Martin R. , Nash Garrett M. , Saltz Leonard , Barlas Afsar , Manova-Todorova Katia , Uppada Srijaya Prakash Babu , Elghouayel Arthur E. , Ntiamoah Peter , Glickman Jonathan N. , Hamada Tsuyoshi , Kosumi Keisuke , Inamura Kentaro , Chan Andrew T. , Nishihara Reiko , Cercek Andrea , Ganesh Karuna , Kemeny Nancy E. , Dhawan Punita , Yaeger Rona , Sawyers Charles L. , Garcia-Aguilar Julio , Giannakis Marios , Shia Jinru , Smith J. Joshua
Published: April 2023

Kaplan-Meier graph with number of subjects at risk comparing (a) SMAD4, (b) TIL, and (c) PLA status, separately, as well as (d) SMAD4 and TIL, and (e) SMAD4 and PLA, together, with recurrence-free survival (RFS) among only the MMR-proficient patients.
Supplementary Table S5 from Loss of SMAD4 Promotes Colorectal Cancer Progression by Recruiting Tumor-Associated Neutrophils via the CXCL1/8–CXCR2 Axis
Authors: Ogawa Ryotaro , Yamamoto Takamasa , Hirai Hideyo , Hanada Keita , Kiyasu Yoshiyuki , Nishikawa Gen , Mizuno Rei , Inamoto Susumu , Itatani Yoshiro , Sakai Yoshiharu , Kawada Kenji
Published: April 2023

Patient and tumor characteristics (n = 99)
Supplementary Figure 5 from Overall Survival in Malignant Glioma Is Significantly Prolonged by Neurosurgical Delivery of Etoposide and Temozolomide from a Thermo-Responsive Biodegradable Paste
Authors: Smith Stuart J. , Tyler Betty M. , Gould Toby , Veal Gareth J. , Gorelick Noah , Rowlinson Jonathan , Serra Riccardo , Ritchie Alison , Berry Phillip , Otto Annette , Choi John , Skuli Nicolas , Estevez-Cebrero Maria , Shakesheff Kevin M. , Brem Henry , Grundy Richard G. , Rahman Ruman
Published: April 2023

Supplementary Figure 5 and Legend
Supplementary Figure 1 from Overall Survival in Malignant Glioma Is Significantly Prolonged by Neurosurgical Delivery of Etoposide and Temozolomide from a Thermo-Responsive Biodegradable Paste
Authors: Smith Stuart J. , Tyler Betty M. , Gould Toby , Veal Gareth J. , Gorelick Noah , Rowlinson Jonathan , Serra Riccardo , Ritchie Alison , Berry Phillip , Otto Annette , Choi John , Skuli Nicolas , Estevez-Cebrero Maria , Shakesheff Kevin M. , Brem Henry , Grundy Richard G. , Rahman Ruman
Published: April 2023

Supplementary Figure 1 and Legend
Supplementary Figure 2 from Loss of SMAD4 Promotes Colorectal Cancer Progression by Recruiting Tumor-Associated Neutrophils via the CXCL1/8–CXCR2 Axis
Authors: Ogawa Ryotaro , Yamamoto Takamasa , Hirai Hideyo , Hanada Keita , Kiyasu Yoshiyuki , Nishikawa Gen , Mizuno Rei , Inamoto Susumu , Itatani Yoshiro , Sakai Yoshiharu , Kawada Kenji
Published: April 2023

Supplementary Figure 2. A, Screening with a series of kinase inhibitors treated for 24 hours. qRT-PCR analysis for CXCL1 (top) and CXCL8 (bottom). B, Chemotactic responses of neutrophils toward the human recombinant CXCL1 and CXCL8. Mean; bars, {plus minus} SD. *P < 0.05 by Student's t-test. C, Neutrophils were isolated from peripheral blood and from CRC specimens of the same patients (n = 6) by FACS with CD45, CD66b, CD14, CD15, and CD16.
Supplementary Data from Calcium Intake and Survival after Colorectal Cancer Diagnosis
Authors: Yang Wanshui , Ma Yanan , Smith-Warner Stephanie , Song Mingyang , Wu Kana , Wang Molin , Chan Andrew T. , Ogino Shuji , Fuchs Charles S. , Poylin Vitaliy , Ng Kimmie , Meyerhardt Jeffrey A. , Giovannucci Edward L. , Zhang Xuehong
Published: April 2023

Supplementary Figure S1. Flow chart of the study population in the Nurses' Health Study (1980-2012) and Health Professionals Follow-up Study (1986-2012) Supplementary Table S1. Total and supplemental calcium intake after cancer diagnosis in relation to mortality among colorectal cancer patients using IPW method Supplementary Table S2. Postdiagnostic calcium supplement use (not including calcium from multivitamin use) and mortality among colorectal cancer patients Supplementary Table S3. Colorectal cancer specific mortality and overall mortality according to join classification of prediagnostic and postdiagnostic calcium intake Supplementary Table S4. Postdiagnostic total calcium intake in relation to mortality among cancer patients Supplementary Table S5. Postdiagnostic calcium intake overall and by food sources and mortality among colorectal cancer patients in the Nurses' Health Study Supplementary Table S6. Postdiagnostic calcium intake overall and by food sources and mortality among colorectal cancer patients in the Health Professional Follow-up Study Supplementary Table S7. Prediagnostic calcium intake and mortality among colorectal cancer patients
Supplementary Figure S2 from Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR+/HER2− Breast Cancer
Authors: Hurvitz Sara A. , Martin Miguel , Press Michael F. , Chan David , Fernandez-Abad María , Petru Edgar , Rostorfer Regan , Guarneri Valentina , Huang Chiun-Sheng , Barriga Susana , Wijayawardana Sameera , Brahmachary Manisha , Ebert Philip J. , Hossain Anwar , Liu Jiangang , Abel Adam , Aggarwal Amit , Jansen Valerie M. , Slamon Dennis J.
Published: April 2023

Ki67 expression in patient tumor specimens.
Table S5 from Colony-Stimulating Factor 1 Receptor (CSF1R) Activates AKT/mTOR Signaling and Promotes T-Cell Lymphoma Viability
Authors: Murga-Zamalloa Carlos , Rolland Delphine C.M. , Polk Avery , Wolfe Ashley , Dewar Hiran , Chowdhury Pinki , Onder Ozlem , Dewar Rajan , Brown Noah A. , Bailey Nathanael G. , Inamdar Kedar , Lim Megan S. , Elenitoba-Johnson Kojo S.J. , Wilcox Ryan A.
Published: April 2023

List of antibodies used for immunoblotting and flow cytometry analysis.
Supplementary Tables from A Transcriptionally Definable Subgroup of Triple-Negative Breast and Ovarian Cancer Samples Shows Sensitivity to HSP90 Inhibition
Authors: Shee Kevin , Wells Jason D. , Ung Matthew , Hampsch Riley A. , Traphagen Nicole A. , Yang Wei , Liu Stephanie C. , Zeldenrust Megan A. , Wang Liewei , Kalari Krishna R. , Yu Jia , Boughey Judy C. , Demidenko Eugene , Kettenbach Arminja N. , Cheng Chao , Goetz Matthew P. , Miller Todd W.
Published: April 2023

Table S1. BRCA and OVCA cell lines analyzed. Cell line data were obtained from the GDSC or CCLE databases as indicated. Table S2. Drug sensitivity analysis for BR/OV-1 vs. -2 cell lines in GDSC. Table S3. BR/OV-1/2 gene expression classifier. Table S4. Gene Ontology (GO) analysis for BR/OV-1/2 classifier genes. Table S5. Subtyping of TNBC cell lines. Table S6. Genes upregulated in BR/OV-2 cells are rarely present in reported mesenchymal gene signatures. Table S7. (Phospho)proteins differentially expressed between BR/OV-1 vs. -2 cells by RPPA. Table S8. Proteins differentially expressed between BR/OV-1 and -2 TNBC cells by MS. Table S9. Gene Ontology (GO) analysis of differentially expressed proteins. Table S10. BR/OV-1/2 Subgroup Scores for 88 BRCA PDX models from 20 patients.
Table S2 from Colony-Stimulating Factor 1 Receptor (CSF1R) Activates AKT/mTOR Signaling and Promotes T-Cell Lymphoma Viability
Authors: Murga-Zamalloa Carlos , Rolland Delphine C.M. , Polk Avery , Wolfe Ashley , Dewar Hiran , Chowdhury Pinki , Onder Ozlem , Dewar Rajan , Brown Noah A. , Bailey Nathanael G. , Inamdar Kedar , Lim Megan S. , Elenitoba-Johnson Kojo S.J. , Wilcox Ryan A.
Published: April 2023

Phosphopeptides detected by mass spectrometry screening in Karpas 299 lines (NH4OH enrichment) after treatment with DMSO or pexidartinib.
Figure S2 from Circulating miRNAs and PD-L1 Tumor Expression Are Associated with Survival in Advanced NSCLC Patients Treated with Immunotherapy: a Prospective Study
Authors: Boeri Mattia , Milione Massimo , Proto Claudia , Signorelli Diego , Lo Russo Giuseppe , Galeone Carlotta , Verri Carla , Mensah Mavis , Centonze Giovanni , Martinetti Antonia , Sottotetti Elisa , Pastorino Ugo , Garassino Marina Chiara , Sozzi Gabriella
Published: April 2023

Figure S2 shows OS in strata of MSC risk level in patients with PD-L1>=50% and with PD-L1<50%
Figure S3 from Colony-Stimulating Factor 1 Receptor (CSF1R) Activates AKT/mTOR Signaling and Promotes T-Cell Lymphoma Viability
Authors: Murga-Zamalloa Carlos , Rolland Delphine C.M. , Polk Avery , Wolfe Ashley , Dewar Hiran , Chowdhury Pinki , Onder Ozlem , Dewar Rajan , Brown Noah A. , Bailey Nathanael G. , Inamdar Kedar , Lim Megan S. , Elenitoba-Johnson Kojo S.J. , Wilcox Ryan A.
Published: April 2023

Methylation-dependent regulation of CSF1R expression.
Supplementary Data from First-in-Human Phase I Study of the Selective MET Inhibitor, Savolitinib, in Patients with Advanced Solid Tumors: Safety, Pharmacokinetics, and Antitumor Activity
Authors: Gan Hui K. , Millward Michael , Hua Ye , Qi Chuan , Sai Yang , Su Weiguo , Wang Jian , Zhang Lilin , Frigault Melanie M. , Morgan Shethah , Yang Liu , Lickliter Jason D.
Published: April 2023

Supplementary Table 1. Summary of the SAEs across all treatment cohorts Supplementary Table 2. Pharmacokinetic parameters (Cmax, AUClast and t1/2) of savolitinib Supplementary Figure 1. Computed tomography images for a patient with PRCC who achieved PR with savolitinib 600 mg QD treatment
Supplementary Data from ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer
Authors: Li Zhuqing , Zhou Wei , Zhang Yi , Sun Wei , Yung Mingo M.H. , Sun Jing , Li Jing , Chen Chi-Wei , Li Zongzhu , Meng Yunxiao , Chai Jie , Zhou Yuan , Liu Stephanie S. , Cheung Annie N.Y. , Ngan Hextan Y.S. , Chan David W. , Zheng Wei , Zhu Wenge
Published: April 2023

Figure S1. Establishment of platinum-resistant ovarian cancer cell lines. Related to Figure 1. Figure S2. YC-1 targets HIF-1α signaling in PROC cells in vitro and in vivo. Related to Figure 2. Figure S3. ERK1/2 regulates HIF-1α activity in ovarian cancer cells. Related to Figure 3. Figure S4. ERK1/2 regulate HIF-1α signaling by directly interacting with and phosphorylating PHD2. Related to Figure 4. Figure S5. TGF-β1 receptor inhibitor SB431542 suppresses ERK/HIF-1α signaling. Related to Figure 5. Figure S6. TGF-β1/ERK/HIF-1α pathway activation in platinum sensitive cell lines when treated with different dosages of cisplatin. Table S1. qHTS data for IGROV CR cells
Supplementary Legend from Tumor-Localized Costimulatory T-Cell Engagement by the 4-1BB/HER2 Bispecific Antibody-Anticalin Fusion PRS-343
Authors: Hinner Marlon J. , Aiba Rachida Siham Bel , Jaquin Thomas J. , Berger Sven , Dürr Manuela Carola , Schlosser Corinna , Allersdorfer Andrea , Wiedenmann Alexander , Matschiner Gabriele , Schüler Julia , Moebius Ulrich , Rothe Christine , Matis Louis , Olwill Shane Anthony
Published: April 2023

Supplementary Legend
Figure S5 from Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade
Authors: House Imran G. , Savas Peter , Lai Junyun , Chen Amanda X.Y. , Oliver Amanda J. , Teo Zhi L. , Todd Kirsten L. , Henderson Melissa A. , Giuffrida Lauren , Petley Emma V. , Sek Kevin , Mardiana Sherly , Gide Tuba N. , Quek Camelia , Scolyer Richard A. , Long Georgina V. , Wilmott James S. , Loi Sherene , Darcy Phillip K. , Beavis Paul A.
Published: April 2023

Figure S5 shows the expression of CXCL9 and CXCL10 mRNA and protein by AT-3ova tumor cells following stimulation with IFNgamma and TNFalpha