bluuebunny/crossref_metadata_2025 huggingface dataset:
Linking crop traits to transcriptome differences in a progeny population of tetraploid potato
Authors: Alexandersson Erik , Kushwaha Sandeep , Subedi Aastha , Weighill Deborah , Climer Sharlee , Jacobson Daniel , Andreasson Erik
Published: October 2019

Background Potato is the third most consumed crop in the world. Breeding for traits such as yield, product quality and pathogen resistance are main priorities. Identifying molecular signatures of these and other important traits is important in future breeding efforts. In this study, a progeny population from a cross between a breeding line, SW93-1015, and a cultivar, Désirée, was studied by trait analysis and RNA-seq in order to develop understanding of segregating traits at the molecular level and identify transcripts with expressional correlation to these traits. Transcript markers with predictive value for field performance applicable under controlled environments would be of great value for plant breeding. Results A total of 34 progeny lines from SW93-1015 and Désirée were phenotyped for 17 different traits in a field in Nordic climate conditions and controlled climate settings. A master transcriptome was constructed with all 34 progeny lines and the parents through a de novo assembly of RNA-seq reads. Gene expression data obtained in a controlled environment from the 34 lines was correlated to traits by different similarity indices, including Pearson and Spearman, as well as DUO, which calculates the co-occurrence between high and low values for gene expression and trait. Our study linked transcripts to traits such as yield, growth rate, high laying tubers, late and tuber blight, tuber greening and early flowering. We found several transcripts associated to late blight resistance and transcripts encoding receptors were associated to Dickeya solani susceptibility. Transcript levels of a UBX-domain protein was negatively associated to yield and a GLABRA2 expression modulator was negatively associated to growth rate. Conclusion In our study, we identify 100’s of transcripts, putatively linked based on expression with 17 traits of potato, representing both well-known and novel associations. This approach can be used to link the transcriptome to traits. We explore the possibility of associating the level of transcript expression from controlled, optimal environments to traits in a progeny population with different methods introducing the application of DUO for the first time on transcriptome data. We verify the expression pattern for five of the putative transcript markers in another progeny population.
A nationwide survey of intraoperative management for one-lung ventilation in Taiwan: time to accountable for diversity in protective lung ventilation
Authors: Kuo Chuan-Yi , Liu Ying-Tung , Lam Chen-Fuh , Wu Ming-Cheng
Published: October 2019

Background: There is a major paradigm shift for intraoperative mechanical ventilator support by the introduction of lung protective ventilation strategies to reduce postoperative pulmonary complications and improve overall clinical outcomes in non-thoracic surgeries. However, there is currently a lack of standardized practice guideline for lung protection during thoracic surgeries that require one-lung ventilation (OLV). This study aimed to collect the expert opinions of the thoracic anesthesiologists in perioperative care for OLV surgery in Taiwan.Methods: This prospective cross-sectional study was undertaken in 16 tertiary hospitals in Taiwan from January to February 2019. A structured survey form was distributed across the participating hospitals and the thoracic anesthesiologists were invited to complete the form voluntarily. The survey form consisted of three parts, including the basic information of the institutional anesthesia care standards, ventilatory settings for a proposed patient receiving OLV surgery and expert opinions on OLV.Results: A total of 71 thoracic anesthesiologists responded to the survey. Double-lumen tubes are the most commonly used (93.8%) airway devices for OLV. The most commonly recommended ventilator setting during OLV is a tidal volume of 6-7 ml/kg PBW (67.6%) and a PEEP level of 4-6 cmH2O (73.5%). Dual controlled ventilator modes are used by 44.1% of the anesthesiologists. During OLV, high oxygen fraction (FiO2 >0.8) is more commonly supplemented to achieve an oxygen saturation higher than 94%. The consensus of anesthesiologists on the indices for lung protection in thoracic surgery is considerably low. Large majority of the anesthesiologists (91.5%) highly recommend that an international clinical practice guideline on the protective lung ventilation strategy for thoracic anesthesia should be established.Conclusions: This study found that the thoracic anesthesiologists in Taiwan share certain common practices in ventilator support during OLV. However, they are concerned about the lack of fundamental clinical evidences to support the beneficial outcomes of the current lung protective strategies applicable to OLV. Large-scale trials are needed to form an evidence-based clinical practice guideline for thoracic anesthesia.
Comparative genomics analysis of c-di-GMP metabolism and regulation in Microcystis aeruginosa
Authors: Chen Meng , Xu Chun-Yang , Wang Xu , Ren Chong-Yang , Ding Jiao , Li Li
Published: October 2019

Background: Cyanobacteria are of special concern because they proliferate in eutrophic water bodies worldwide and affect water quality. As an ancient photosynthetic microorganism, cyanobacteria can survive in ecologically diverse habitats because of their capacity to rapidly respond to environmental changes through a web of complex signaling networks, including using second messengers to regulate physiology or metabolism. A ubiquitous second messenger, bis-(3′,5′)-cyclic-dimeric-guanosine monophosphate (c-di-GMP), has been found to regulate essential behaviors in a few cyanobacteria but not Microcystis, which are the most dominant species in cyanobacterial blooms. In this study, comparative genomics analysis was performed to explore the genomic basis of c-di-GMP signaling in Microcystis aeruginosa.
Results: General characterization along with a pan-genome analysis showed that M. aeruginosa have a medium size genome (4.99 Mb in average), a conserved core genome, and an expansive pan-genome. Phylogenetic analysis showed good overall congruence between the two types of phylogenetic trees based on 31 highly conserved protein-coding genes and pan-genome matrix. Furthermore, phylogenetic analysis revealed no correlation between geographic distribution and phylogenetic relationships of the M. aeruginosa strains isolated from different regions. Moreover, proteins involved in c-di-GMP metabolism and regulation, such as diguanylate cyclases, phosphodiesterases, and PilZ-containing proteins, were encoded in M. aeruginosa genomes. It was revealed that the numbers of genes that encode diguanylate cyclases, phosphodiesterases, and hybrid proteins with GGDEF-EAL domains in M. aeruginosa might result from environment-specific adaptation. Bioinformatics and structure analysis of c-di-GMP signal-related GGDEF, EAL and GGDEF-EAL domains revealed that they all possess essential conserved amino acid residues that bind the substrate. In addition, it was also found that all selected M. aeruginosa genomes encode PilZ domain containing proteins.
Conclusions: Comparative genomics analysis of c-di-GMP metabolism and regulation in M. aeruginosa strains helped elucidate the genetic basis of c-di-GMP signaling pathways in M. aeruginosa. Knowledge of c-di-GMP metabolism and relevant signal regulatory processes in cyanobacteria can enhance our understanding of their adaptability to various environments and bloom-forming mechanism.
Keywords: Microcystis aeruginosa, Comparative genomics, c-di-GMP, Phylogenetic analysis, GGDEF, EAL, PilZ
Induction techniques that reduce redistribution hypothermia: A prospective, randomized, controlled, single blind effectiveness study.
Authors: Roth Jonathan , Braitman Leonard E , Hunt Lacy H.
Published: October 2019

BACKGROUND
While much effort has been devoted to correcting intraoperative hypothermia, less attention has been directed to preventing redistribution hypothermia. In this study, we compared three different anesthetic induction techniques to standard IV propofol inductions (control) in their effect on reducing redistribution hypothermia.
METHODS
Elective, afebrile patients, age 18 to 55 years, were randomly assigned to one of four groups (n=50 each). Group “INH/100” was induced with 8% sevoflurane in 100% oxygen, Group “INH/50” with 8% sevoflurane in 50% oxygen and 50% nitrous oxide, Group “PROP” with 2.2 mg/kg propofol, and Group “Phnl/PROP” with 2.2 mg/kg propofol immediately preceded by 160 mcg phenylephrine. Patients were maintained with sevoflurane in 50% nitrous oxide and 50% oxygen in addition to opioid narcotic. Forced air warming was used. Core temperatures were recorded every 15 minutes after induction for one hour.
RESULTS
Compared to control group PROP, the mean temperatures in groups INH/100, INH/50, and Phnl/PROP were higher 15, 30, 45 and 60 minutes after induction (p<0.001 for all comparisons), averaging between 0.39oC and 0.54oC higher. In group PROP, 60% of patients had at least one temperature below 36.0oC in the first hour whereas only 16% did in each of groups INH/100, INH/50, and Phnl/PROP (p<0.0001 in each group compared to PROP).
CONCLUSIONS
In this effectiveness trial, inhalation inductions with sevoflurane or with prophylactic phenylephrine bolus prior to propofol induction reduced the magnitude of redistribution hypothermia by an average of 0.4 to 0.5°C in patients aged 18 to 55 years.

Retrospectively registered on clinical-trials.gov as NCT02331108, November 20, 2014.
Abstract uploaded to:
http://www.persistent-identifier.nl/?identifier=urn%3Anbn%3Anl%3Aui%3A13-lo-lchp
Teatro Cultura Artística: a recuperação de um patrimônio
Authors: De Pietro Rosane Martins , Giraldi Rita De Cássia
Published: October 2019

Este artigo trata do processo de reconstrução do Teatro Cultura Artística, inaugurado em 1950 em São Paulo. Com projeto arquitetônico de Rino Levi e mosaico do artista plástico Emiliano Di Cavalcanti, o teatro modernizou o padrão das salas de espetáculo e propiciou a popularização da cultura na região central da cidade. Em decorrência de um incêndio ocorrido em 2008, o edifício sofreu perda estrutural, mantendo íntegra somente sua fachada voltada para o espaço público, identificada pela memória paulistana no painel modernista de Di Cavalcanti. Fundamentada nas etapas do processo de tombamento histórico do teatro, a análise aqui apresentada discute correntes de preservação, técnicas de restauração e políticas de revitalização urbana praticadas na atualidade.
Round table “Progress of Russia: women's aspect“ (Moscow, May 15, 2018)
Authors: Лебедева Елена , Lebedeva Elena
Published: October 2019

The roundtable discussion “Progress of Russia: women's aspect” was attended by prominent Russian scholars, researchers and university tutors. The reports of the participants focused on women personalities – scientists, public figures, great women of Russia. Their role in the achievements of national and global science was highly appreciated.
Core Values and Their Reflection in the Speech of the Ural City
Authors: Вепрева Ирина , Vepreva Irina , Купина Наталия , Kupina Natalia , Ицкович Татьяна , Itskovich Tatiana
Published: October 2019

The research outlines the findings of collaborative insights into the core values anchored in the linguistic consciousness of people living in the Urals and represented across diverse areas of speech in the cities of the Middle Urals. The purpose of the study is to understand the linguoaxiologic reality of the current times, interpret representatives of value concepts with a consolidating function.

To reach the target, the authors have practiced sociolinguistic monitoring helping to reveal value preferences among the student youth. Using the complementation principle, they have conducted a psycholinguistic experiment aimed at identifying nuclear and peripheral conceptual meanings anchored in the linguistic consciousness. The findings helped to conclude: the core of basic values is a system of interrelated conceptual meanings organized as a cognitive matrix.

Based on a meaningful interpretation of the materials used in the experiment, the authors managed to identify the increase in the divergent self-mentality of a subject with free consciousness focused on self-fulfillment and pursuing personal goals. However, at the emotional level, young people stay committed to the socio-centric traditions of the Russian culture: family interests (we-group) prevail over individual interests.

The linguoaxiologic analysis of municipal newspaper texts and methods of metalanguage study helped to describe the value aspects of provincial thinking: native speakers feel both as Uralians and Russians with preserved national, primarily, family traditions. The core value of the urban provincial community is little homeland — a key category of the Ural mentality. The mentally relevant mindsets are those related to common good.

Using conversation scripts reflecting the distinctive features of speech communication in the Urals, the authors divide the value-thematic and communicative-value text fragments, develop an algorithm for linguoaxiological commenting on oral dialogue.
19th Theoretical and Methodological Conference Life Purposes of the Russian Intelligentsia (Moscow, 26 April, 2018)
Authors: Тощенко Жан , Toschenko Zhan , Цапко Мирослава , Capko Miroslava
Published: October 2019

The conference discussed the issues of the background knowledge of the modern Russian intelligentsia. The basis of its analysis was the modes of time: past, present and future. It is from this perspective that the life purposes of various social groups and communities of the intelligentsia were considered.
Academic Conference Dedicated to B.G. Yudin Man in the World of Neurotechnologies: Social & Ethical Issues (Moscow, 30–31 May, 2018)
Authors: Тищенко Павел , Tischenko Pavel , Гребенщикова Елена , Grebenschikova Elena
Published: October 2019

The fruitful development of neuroscience is not feasible without prompt diagnosis, assessment and development of technologies for the management of social and humanitarian risks of neuroscience discoveries and inventions. The first national conference on neuroethics will serve as a stimulus for its development in our country as a stand-alone research area, will contribute to favorable social environment for the innovative development of interdisciplinary studies of the human brain.
International Academic Conference A Book in the Modern World: Reception Issues (Voronezh, 27 February — 1 March, 2018)
Authors: Попова Мария , Popova Mariya
Published: October 2019

The paper describes the key takeaways of the conference and researches various aspects of book existence in the today’s world (book and knowledge, small circulation, text and illustration, book and movie) and its formats (artist’s book, audiobook, electronic book).
The Sverbeev Family Epistolary Archive
Authors: Медведева Татьяна , Medvedeva Tat'yana
Published: October 2019

The article is focused on the Sverbeev family epistolary archive study findings. Especially, this means letters of D.N. Sverbeev (1799–1874), a memoirist, and E.A. Sverbeeva (1808–1892), his wife, a hostess of the famous Moscow salon in 1840s, who had extensive ties to the Russian enlightened society. Epistolary intercourse of their sons and daughters (in particular, N.D. Sverbeev, A.D. Sverbeev and S.D. Sverbeeva) inherited and successfully maintained parents’ social ties is also of interest. The family archive maintained abundant correspondence with family friends and acquaintances including Turgenev brothers (i.e., A.I. and N.I.), K.S. and I.S. Aksakovs, N.M. and A.M. Yazykovs, archbishop Innokentii (Veniami­nov), A.N. Popov, A.S. Homyakov, I.V. Kireevskii, A.P. Elagina, S.P. Shevyryov, P.A. Vyazemskii, S.P. Trubetskoi, etc.

Almost centenary epistolary archive of a whole family maintained remarkable social ties represents an important document of cultural memory and literary history of two generations of the Russian noble intellectuals in the XIX century. Philosophical, literary, religious and pedagogical issues are discussed in correspondence of the Sverbeev family. It demonstrates responses to the most important social and cultural events of the epoch. Also, it contains biographic, cultural and social data. Also, the Sverbeev family epistolary archive enables a comparative study of private correspondence.
Equivalenting Dynamic Inter-Sectoral Balance in Sustainability Issues
Authors: Торопцев Евгений , Toropcev Evgeniy , Мараховский Александр , Marahovskiy Aleksandr
Published: October 2019

Since 2017, the Federal State Statistics Service (Rosstat) has published “cost-output” tables on its website. Together with some parts of its statistical database of studies, this helps to create dynamic inter-branch models of a sufficiently high dimension. These models are designed to tackle issues of stability, analysis and improvement of the own dynamic properties of economic systems. Models can be used either independently or integrated into complexes with computable equilibrium models abbreviated as CGE (Computable General Equilibrium), as well as with other agent-focused models. Improvement here is driven by the active use of the theory and methods of linear algebra, differential equations, and operations research. The need to repeatedly solve the complete eigenvalue problem on this path makes the improvement algorithm computationally challenging. Still, among the defined components of the movement, determined by the structure of the economy, there are those uncontrolled and poorly controlled by the parameters of regulation. This makes relevant a formalized reduction of the dimension of the original model, adequate to the problem being solved. The paper introduces a technique of equivalenting high-dimensional dynamic inter-industry models for effective work as part of improving algorithms for the intrinsic/internal dynamic properties of economic systems.
Comparison of Implementation of Computation of Video Image Displacement Vectors in Built-in Systems
Authors: Ushakov P. A. , Pechenkin A. Yu.
Published: October 2019

В работе рассмотрены алгоритмы вычисления векторов смещения видеоизображений, которые находят применение в смартфонах, цифровых фотокамерах, различных специализированных изделиях для стабилизации изображений, контроля дорожного движения, при аэрофотосъемках, при сопровождении объектов и в других приложениях. Для сравнительной оценки эффективности использования вычислительных ресурсов при реализации алгоритмов вычисления векторов смещения были выбраны: алгоритм на основе метода Лукаса – Кэнейда и алгоритм, основанный на согласованной фильтрации изображения. Определялось глобальное смещение изображения с использованием аппаратной платформы - системы на кристалле Xilinx семейства Ultrascale+. Матричные вычисления алгоритма Лукаса – Кэнейда были реализованы 4 одинаковыми аппаратными блоками, что позволило вычислять смещения между кадрами одновременно для 4 точек. В этом случае время вычисления оптического потока составило в среднем 7,5 мс. В реализации алгоритма согласованной фильтрации изображения на базе ДДПФ также использовалось 4 аппаратных блока, позволяющих распараллелить вычисления. В результате время работы алгоритма составило 2,9 мс, при этом процессорное время, необходимое для работы алгоритма, составило 0,2 мс. В процессе реализации определены слабые места алгоритмов, необходимое количество аппаратных ресурсов системы на кристалле. Показано, что при наличии достаточных аппаратных ресурсов определение смещения соседних кадров видеоряда гораздо эффективнее реализуется на базе согласованной фильтрации, чем алгоритмом Лукаса – Кэнейда.
Расчетное исследование параметров механической безопасности высотного (404 метра) жилого комплекса «One Tower» в деловом центре «Москва-Сити»
Authors: Belostotsky Alexander , Akimov Pavel , Dmitriev Dmitry , Nagibovich Alexander , Petryashev Nikolay , Petryashev Sergey
Published: October 2019

Рассматриваемый в настоящей статье высотный жилой комплекс «One Tower» высотой 403,9 метра будет располо­жен в Московском международном деловом центре (ММДЦ) «Москва-Сити» и станет одним из самых высоких зданий в Европе. Архитектурный проект уникального объекта был разработан в архитектурном бюро «Сергей Скуратов Architects», конструктивная часть - ООО «Техстрой» (под руководством М.И. Кельмана). Статья посвящена расчётным исследованиям напряжённо-деформированного состояния, прочности и устойчивости несущих конструкций этого мно­гофункционального жилого комплекса с подземной авто­стоянкой. Приведено краткое описание природных условий района расположения объекта, его несущих конструкций, нагрузок (расчётных и нормативных, основных и особых) и их сочетаний, представлена постановка задач расчётных ис­следований. Далее кратко описаны использовавшиеся чис­ленные методики, алгоритмы и реализующее программно­алгоритмическое обеспечение для расчёта статического и динамического напряжённо-деформированного состояния. Представлены разработанная и верифицированная подроб­ная конечноэлементная модель системы «свайное основа­ние - несущие конструкции жилого комплекса», адекватно отражающая его геометрико-жесткостные, инерционные и нагрузочные характеристики и результирующее напряжён­но-деформированное состояние, а также результирующие параметры напряжённо-деформированного состояния, прочности и динамики несущих конструкций объекта при нормативно регламентированных сочетаниях вертикальных и ветровых нагрузок, а также расчёты на устойчивость про­тив прогрессирующего обрушения. В заключении на базе выполненных исследований делается обоснованный вывод о достоверности полученных расчётами критериальных параметров, определяющих прочность, устойчивость и дина­мику несущих конструкций объекта. Все основные расчёты были проведены с использованием лицензионного конеч­ноэлементного программного комплекса ANSYS Mechanical, верифицированного в Российской академии архитектуры и строительных наук (РААСН). Армирование конструкций по конвертированным результирующим усилиям (из расчётов по ANSYS Mechanical) проводилось в программном комплек­се «ОМ СНиП Железобетон».
Круг средового знания и его сегментация в теории архитектуры
Authors: Kiyanenko Konstantin
Published: October 2019

Рассматривается раздел российской теории архитек­туры, ассоциируемый со средовой парадигмой. Исходя из отмечаемого рядом исследователей факта неоднородности этой сферы знания, автор пытается выделить и рассмотреть формирующие её проблемно-тематические поля, проследить специфику средового видения, истоки и причины своеобра­зия теоретических установок. Различия в трактовке базовых понятий («среда», «средовое проектирование», «средовой подход» и др.), внимание к разным теоретико-методологиче­ским основаниям и дисциплинам (от философии и методо­логии деятельности до психологии зрительного восприятия и средовой психологии, от экспериментальной эстетики до искусствознания), разное толкование адептами средового видения решаемых профессиональных и социокультурных проблем (от композиционной контекстуальности архитек­турных решений до соучаствующего проектирования, от преодоления узости функционалистского видения жизни до обеспечения экологических стандартов) показывают на­личие семи сегментов средового знания. С использованием самоназваний некоторых сегментов они могут быть обозначены как «дизайн архитектурной среды», «исследование потребностей пользователей», «социально-культурные ис­следования городской среды», «исследования методологии проектирования», «исследования визуального восприятия», «поведенческо-средовые исследования» и «архитектурно­экологические исследования». С использованием ресурса Научной электронной библиотеки России (НЭБ) подвергнуты наукометрическому анализу «ключевые слова», аннотации и списки цитируемой литературы примерно 2500 публикаций, а в ряде случаев проведён понятийно-терминологический ана­лиз полных текстов средового раздела теории архитектуры. Показано, что авторы могут мигрировать между сегментами, в разных своих работах демонстрировать приверженность цен­ностям разных средовых платформ, но определённость теоре­тических установок каждой из них при этом не нарушается.
Агротуризм как стимул развития сельских территорий
Authors: Korobova Olga
Published: October 2019

Одной из важнейших стратегических целей государственной политики, является создание условий для устойчивого развития сельских территорий, сохранение существующих сельских по­селений во всём многообразии сложившихся форм сельского расселения. Развитие туристической инфраструктуры в сельской местности и, в частности агротуризм, может стать одним из фак­торов, способствующих диверсификации сельской экономики, повышению занятости и доходов сельского населения; развитию малого бизнеса, в том числе в альтернативных сферах занятости, а следовательно, повышению качества жизни на селе.

В Федеральной целевой программе «Развитие внутреннего и въездного туризма в Российской Федерации на 2011-2018 гг.» сельский туризм назван новым перспективным направлением. В Распоряжении правительства от 30 ноября 2010 года № 2136- р «О Концепции устойчивого развития сельских территорий Российской Федерации на период до 2020 года» агротуризм трактуется как одно из важнейших направлений в решении занятости сельского населения и перспективное направление в развитии села.

В статье рассматривается зарубежный и отечественный опыт организации этого вида деятельности. Анализируются потенциал и реальные возможности развития агротуризма в России[1].

 

[1] Исследование выполнено в рамках Государственной программы Российской Федерации «Научно-технологическое развитие Российской Федерации» и Про­граммой фундаментальных научных исследований государственных академий наук на 2013-2020 годы по Плану фундаментальных научных исследований Российской академии архитектуры и строительных наук и Министерства строительства и жи­лищно-коммунального хозяйства Российской Федерации, тема № 4.3.8.
OBSERVACIÓN DE ANÉLIDES POR EL MÉTODO DE RÍO HORTEGA, MODIFICADO
Authors: Zaror Cornejo Luis Conrado
Published: October 2019

Es conocido ampliamente el uso de la conidiogénesis en la taxonomía de los hongos anamórficos. Una zona anelídica, puede ser indistinguible por esta metodología, causando confusión en la aplicación del término “anelídico” o “fialídico”.Se presenta una técnica basada en la combinación de la acción de microondas con el método de impregnación de argéntica de Río Hortega, modificado por Piva y colaboradores para dermopatología, aplicado a hongos anelídicos. Es de bajo costo, rápida, para demostrar los hongos anelídicos, en forma segura y reproducible, con un alto grado de definición en los detalles, en microscopio óptico de campo claro. El método de impregnación argéntica, usando un horno microondas doméstico durante 30 segundos, aplicado a ocho especies de hongos anelídicos, tuvo un porcentaje de éxito promedio de un 61%, lográndose una técnica más corta con un alto grado de definición de las zonas aneladas. El promedio sube al 97% al no considerar las especies de Exophiala. Los mejores resultados se obtuvieron con Scopulariopsis, Scedosporium y Hortaea. No se logró éxito en la observación de anelación en especies de Exophiala.
A Pilot Project Exploring Medical Students’ Barriers to Screening for Intimate Partner Violence and Reproductive Coercion
Authors: Stumbar Sarah E. , Ward-Peterson Melissa , Lupi Carla S.
Published: October 2019

Background: Multiple studies have shown that the majority of health care practitioners do not routinely screen for intimate partner violence (IPV); lack of provider preparedness and education is an often-cited barrier to screening. Our third-year family medicine clerkship includes a pregnancy options counseling objective structured clinical examination (OSCE) that requires students to review a preencounter online educational module that highlights screening guidelines for IPV and reproductive coercion. The goal of this study was to explore students’ internal barriers to screening patients for IPV and reproductive coercion, and whether our curricular interventions adequately addressed these barriers.
Methods: We administered an immediate postencounter, anonymous, online survey with open-ended and Likert-type questions to 118 medical students during the 2016 academic year. We used an exploratory, iterative process to analyze qualitative responses and quantify recurrent and commonly identified themes.
Results: After the OSCE, students reported they were more likely to screen for IPV (94%) and reproductive coercion (82%) in future encounters. Qualitative analysis revealed two major types of barriers to screening: internal barriers concerning the screening inquiry itself and concerns regarding handling of patients’ responses.
Conclusions: The online preparatory module and subsequent OSCE provided a low-stakes environment in which to practice screening. However, student comments about their barriers to screening suggest that a first or early curricular intervention folding IPV and reproductive coercion into an educational module on pregnancy options counseling did not optimally promote this screening behavior.
DETERMINATION OF WATER CONTENT IN TEA SAMPLES OF CYMBOPOGON CITRATUS S., MATRICARIA RECUTITA L., MENTHA SPP. AND PIMPINELLA ANISUM L. THROUGH GRAVIMETRIC AND THERMOGRAVIMETRIC METHODS
Authors: Fantoni Maciel Pedro , Steppe Martin
Published: October 2019

The excess of humidity in materials of plant origin allows the action of enzymes, which can cause degradation of chemical components and enable fungi and bacteria development. The humidity determination is one of the most important and most used measurements in food analysis, as it is tightly related to food quality, stability and composition. Teas are among humanity’s most popular and most broadly diffused drinks, being the most common form of phytoterapeutical products and a natural source of chemical substances with activity against a broad variety of ailments. Humidity determination in teas of Cymbopogon citratus S., Matricaria recutita L., Mentha spp. and Pimpinella anisum L was performed through pharmacopoeia-standards gravimetric analysis, drying by infrared radiation and thermogravimetry, and the results obtained by each method were compared. All humidity indexes obtained were in accordance with the currently available official specifications. Water content values obtained by the pharmacopoeia-standards assay, infrared radiation assay and thermogravimetry presented statistical difference between them, due to the methods’ technical features or the utilized materials’ physical characteristics; still the thermogravimetry and the infrared radiation assay were the methods that presented the least statistical difference between their results. The pharmacopoeia-standards method presented itself as the more adequate method for the determination of water content in materials of plant origin, like teas.
GREEN ANALYTICAL METHOD FOR QUANTIFICATION OF SECNIDAZOLE IN TABLETS BY FOURIER-TRANSFORM INFRARED SPECTROSCOPY (FTIR)
Authors: Souza Lima Jéssica Gonçalves , De Marco Bianca Aparecida , Salgado Hérida Regina Nunes
Published: October 2019

Secnidazole is a medicine widely used in the treatment of bacterial and protozoal diseases. The free sale of this drug allows its easy access to the population and for this reason, the studies that involve the analysis of the quality control of this drug are extremely important to keep the results safe and reliable. Considering the great pharmacotherapeutic application of secnidazole and the great importance of developing new analytical methods that contribute to the environmen, the study was based on the development and validation of a new sustainable analytical method by Fourier-transform infrared spectroscopy (FT-IR) to identify and quantify secnidazole tablets. The method was duly validated according to the ICH guidelines, presenting precision, accuracy, selectivity, robustness and linearity in the concentration range of 0.5-1.3 mg/pellet. The application of this method in addition to being safe and reliable is highly favorable from an economic point of view since there is a significant reduction in the use of production costs as solvents and raw material, being fast and simple and can also be applied to other medicines.
BIOTRANSFORMATION OF METRONIDAZOLE BY CUNNINGHAMELLA ELEGANS ATCC 9245
Authors: Sorrentino Julia Medeiros , Sponchiado Rafaela Martins , Dos Santos Natália Olegário , Oliveira Sendy Salles , Galle Karina , Garcia Cassia Virginia , Fuentefria Alexandre Meneghello , Steppe Martin
Published: October 2019

Drug biotransformation studies appear as an alternative to pharmacological studies of metabolites, development of new drug candidates with reduced investment as well as the most efficient production of chemical structures involves and drug quality control studies. A wide range of reactions in biotransformations process is catalyzed by microorganisms. Fungi can be considered as a promising source of new biotransformation reactions. The aim of this study was to evaluate the capacity of metronidazole biotransformation through the filamentous fungus Cunninghamella elegans ATCC 9245. The monitoring of metabolite formation was performed by high-performance liquid chromatography (HPLC) coupled to ultraviolet (UV) spectrophotometry. The results of the biotransformation of metronidazole showed drug consumption in culture and the formation of four new chromatographic peaks of chemical structures not elucidated. The method showed it became linear over 10-70 μg/mL (r = 0.999953). Accuracy, precision and stability studies agree with international guidelines.  Results are consistent in accordance with the principles of green chemistry as the experimental conditions had a low environmental impact, and few solvents use.
PENGARUH PENERAPAN MEDIA AUDIOVISUAL TERHADAP PEMAHAMAN KONSEP DAN KETERAMPILAN SOSIAL DALAM PEMBELAJARAN IPS PADA SISWA KELAS VII SMP GANESHA DENPASAR
Authors: Damayanti Ni Nyoman , Sukadi Sukadi , Kertih I Wayan
Published: October 2019

Penelitian ini bertujuan sebagai berikut. 1. Menguraikan pengaruh penerapan mediaaudiovisual dalam pembelajaran IPS  terhadap tingkat pemahaman konsep IPS dan keterampilan sosial siswa secara simultan pada siswa  kelas VII SMP Ganesha Denpasar. 2. Menjelaskanpengaruh penerapan media audiovisual dalam pembelajaran IPS terhadap  tingkat pemahaman konsep IPS pada siswa  kelas VII SMP Ganesha Denpasar. 3. Menjelaskanpengaruh penerapan media audiovisual dalam pembelajaran IPS terhadapketerampilan sosialpada siswa  kelas VII SMP Ganesha Denpasar. Untuk mencapa tujuan ini, penelitian ini dilakukan dengan penelitian eksperimen semu menggunakan rancangan the randomized control group with posttest only design pada dua kelas VII di SMP Ganesha Denpasar: satu kelas sebagai kelas eksperimen dan satu kelas sebagai kelas kontrol. Jumlah sampel penelitian ini adalah 79 orang siswa. Ubahan bebas dalam penelitian ini adalah pembelajaran IPS dengan bantuan media audiovisual dan pembelajaran konvensional, sedangkan ubahan terikatnya adalah pemahaman konsep IPS dan keterampilan sosial siswa. Pengumpulan data dalam penelitian ini menggunakan tes objektif pilihan ganda dan form penilaian diri keterampilan sosial. Data hasil penelitian ini dianalisis secara deskriptif dan dengan Manova satu jalur. Hasil penelitian ini menunjukkan sebagai berikut. 1. Ada pengaruh penerapan mediaaudiovisual dalam pembelajaran IPS yang signifikan  terhadap tingkat pemahaman konsep IPS dan keterampilan sosial siswa secara simultan pada siswa  kelas VII SMP Ganesha Denpasar. 2. Ada pengaruh penerapan media audiovisual dalam pembelajaran IPS yang signifikan terhadap  tingkat pemahaman konsep IPS pada siswa  kelas VII SMP Ganesha Denpasar. 3. Ada pengaruh penerapan media audiovisual dalam pembelajaran IPS yang signifikan terhadapketerampilan sosialpada siswa  kelas VII SMP Ganesha Denpasar.Kata Kunci: Media Audiovisual, pemahaman konsep IPS, dan keterampilan sosial siswa
Impact of climate change on ivy (Hedera helix L.) expansion in forests of Central Poland
Authors: Kucharski Leszek , Kloss Marek , Sienkiewicz Jadwiga , Liszewska Małgorzata , Kiełtyk Piotr
Published: October 2019

The article refers to a broader context of scientific debates on the effect of climate warming on shifts in species ranges and describes the recent changes in the distribution and life strategy of Hedera helix close to its eastern limit, in light of climate changes. European ivy is an ecotone species, occurring in fringe communities, in deciduous and mixed deciduous forests in fresh and moist habitats that are occupied by oak-hornbeam and riparian alder-ash forests in Central Poland. Since the mid-20th century, the ivy, a species rarely reproducing generatively, has become an expansive plant with a growing number of sites where flowering and fruiting individuals are encountered. We studied the distribution, habitat requirements and flowering of H. helix in Central Poland in the years 2015–2017 and compared to the situation in the mid-1970s. Climate changes in terms of average air temperatures and precipitation amounts for the past four decades were also assessed. Within the study area, 474 stands of naturally growing Hedera have recently been identified. Ivy was found to reproduce generatively on 121 of those locations. There has been an almost 10-fold increase in the number of fruiting ivy specimens since the mid-1970s of the 20th century. Changes in the species life strategy can be ascribed to the increase in both average air temperatures and solar radiation intensity observed for the past decades. Both enhanced fragmentation of woodland tracts and development of forest ecotones and forest canopy openings promote the expansion of H. helix, while its habitat preferences remain unchanged.
Constitutional aspects of the reform of the Polish justice system in 2017–2018
Authors: Radajewski Mateusz
Published: October 2019

The article concerns the issue of constitutionality of the reform of the justice system in Poland in 2017–2018, which resulted in significant changes of the functioning of the National Council of the Judiciary and the Supreme Court. When discussing the reform of the Supreme Court, the author first of all points to the constitutional problems associated with the premature retirement of some of its judges, which is also connected with the interruption of the six-year term of the First President of the Supreme Court. A separate issue discussed in the article is the introduction to the Supreme Court the lay judges, which is a unique phenomenon on the global scale. The analyses lead the author to formulate final conclusions, also referring to the European regulations and to refer to the unconstitutionality of the solutions adopted by the Polish parliament.
Limitations on the Choice of Law Resulting from the Protection of Third Parties in the Polish System of Private International Law
Authors: Dorabialska Anna
Published: October 2019

The article concerns the limitations of the freedom of shaping the legal relationship by the parties on the grounds of private international law binding in Poland. It is devoted to the specific issue of limitations of the effects of the choice of law on the grounds of the protection of third parties. The rules related to this issue have been included both in the sources of European law (“Rome I” and “Rome II” regulations, as well as in the Polish law – Private International Law of 2011). They concern the choice of law for contractual and non-contractual obligations, for a power of attorney and for matrimonial property regimes. The purpose of these rules is to protect the knowledge of a third party or the rights acquired by them. The article considers various possibilities to exclude the effectiveness of a law chosen for the protection of a third party, while respecting the wills of the parties to the legal relationship as much as possible.
The Kelsenian Model of Constitutional Review in Times of European Integration – Reconsidering the Basic Features
Authors: Kustra-Rogatka Aleksandra
Published: October 2019

The paper deals with the changes in the centralized (Kelsenian) model of constitutional review resulting from a state’s membership of the EU, which unequivocally demonstrates the decomposition of the classic paradigm of constitutional judiciary. The main point raised in the paper is that European integration has fundamentally influenced on the four above-mentioned basic elements of the Kelsenian model of constitutional review of legislation, which are the following: the assumption of the hierarchical construction of a legal system; the assumption of the supreme legal force of the constitution as the primary normative act of a given system; a centralised model of reviewing hierarchical conformity of legal norms; coherence of the system guaranteed by a constitutional court’s power to declare defectiveness of a norm and the latter’s derogation. All its fundamental elements have evolved, i.e. the hierarchy of the legal system, the overriding power of the constitution, centralized control of constitutionality, and the erga omnes effect of the ruling on the hierarchical non-conformity of the norms. It should be noted that over the last decade the dynamics of these changes have definitely gained momentum. This has been influenced by several factors, including the “great accession” of 2004, the pursuit of formal constitutionalization of the EU through the Constitutional Treaty, the compromise solutions adopted in the Treaty of Lisbon, the entry into force of the Charter, and the prospect of EU accession to the ECHR. The CJEU has used these factors to deepen the tendencies towards decentralization of constitutional control, by atomising national judicial systems and relativizing the effects of constitutional court rulings within national legal systems. The end result is the observed phenomenon, if not of marginalisation, then at least of a systemic shift in the position of constitutional courts, which have lost their uniqueness and have become “only ones of many” national courts.
Conditions and Directions of Marketing Activities in Polish Research Institutes
Authors: Maślanka Marlena Elżbieta
Published: October 2019

The offer of institutes is specific and requires the application of special solutions in the area of marketing and new economic conditions in which research institutes operate right now stimulate introducing new solutions and taking advantage of new directions in the area of marketing activity.

The influence of a continuous process of globalization on taking actions in the area of marketing constitutes a major research problem, which requires deepened, detailed analysis and carrying out research in this area. The goal of this article will be to find out to what extent new economic reality makes it necessary to take marketing actions and in what directions within the scope of this activity the research institutes should be going.
Influencers as Support for Public Relations Campaigns
Authors: Tworzydło Dariusz , Życzyński Norbert , Wajda Marek
Published: October 2019

The article is a collection of analyses carried out on the basis of literature on the subject and data collected with the utilization of desk research method. It also presents conclusions from surveys conducted by means of a qualitative method — IDI technique — during the Congress of Public Relations Professionals, which took place in April 2018 in Rzeszów. In the group of respondents there were representatives of public relations branch who cooperate with influencers and on top of that have rich experience in the area of PR activities conducted by means of the Internet. The goal of this article is assessment of the relationships occurring in the context of cooperation of PR specialists with influencers, as well as identifying the prospects for changes and potential trends in this area.

Among the key conclusions drawn in course of the conducted research we find the one which suggests that using influencers for communication and promotion-related activities is recognized as both a chance and threat for the public relations industry. However, the aspect of threats is particularly important, as it has a direct impact on the emerging and persisting image crises. Due to the fact that influencers enjoy a lot of freedom in their activity in combination with the faith of their clients in their professional approach, there is a risk of emergence of actions which will not just fail to satisfy the assumptions of a promotional campaign, but may also directly hit the image of a given entity.

Experts predict that using influencers for promotion will also in the nearest time be a growing trend, which will take hold among solutions used in communication with target groups.
Associations with the University as an Employer in the Years 2016–2019 — Young Potential Employees Perspective
Authors: Baruk Agnieszka Izabela
Published: October 2019

The article is theoretical and empirical. To prepare the theoretical part, the method of cognitive-critical analysis of world literature in the field of management, personal marketing, etc. was applied. Based on the results of this analysis, it can be concluded that there is a cognitive and research gap relating to research on universities as employers. This applies especially to associations of young potential employees with this group of employers. Therefore, the article aims to achieve the goal, which is to identify associations of young potential employees with the university as a workplace and indicate the changes taking place in them. In order to achieve this goal, three editions of empirical research were conducted, using the survey method to collect primary data. The collected data were subjected to quantitative analysis using statistical analysis methods. Its results indicate that there has been a slight improvement in terms of associations of respondents with the university as a workplace. Still, however, more than half of the respondents did not take into account taking up employment in such institutions. Therefore, it is still not an attractive employer for young Poles, which indicates the need to undertake comprehensive activities related to building a positive image as an employer.
PEMBERIAN SANKSI ADAT KEPADA PELAKU PENCURIAN PRATIMA DI BALI
Authors: Wijaya Pande made kresna
Published: October 2019

Ujung dari suatu penegakan hukum adalah pemberian sanksi terhadap pelaku tindak pidana. Di Bali terdapat tindak pidana pencurian dimana benda yang menjadi objek tindak pidana adalah Pratima (Benda sakral). Ketentuan pada KUHP tidak mengatur secara jelas penjatuhan sanksi adat, oleh karena itu penjatuhan sanksi pidana biasa kepada pelaku tindak pidana yang tergolong tindak pidana adat terkadang belum bisa menyelesaikan permasalahan yang terjadi. Tujuan penelitian ini adalah untuk menganalisa terkait pencurian pratima dalam perspektif hukum pidana adat dan dasar hukum pemberian sanksi adat. Penelitian ini mempergunakan metode penelitian normatif. Kemudian menggunakan pendekatan perundang-undangan dan pendekatan konseptual serta menggunakan teknik argumentasi hukum dalam pembahasannya.

Bahwa pencurian pratima lebih tepat dikaitkan dalam perspektif tindak pidana adat, karena dampak dari pencurian pratima tersebut tidak hanya pada kerugian materiil saja melainkan kerugian immateriil dimana dapat mengganggu keseimbangan di masyarakat.

Penerapan sanksi adat untuk penyelesaian tindak pidana pencurian pratima di Bali dapat dilakukan karena eksistensi hukum pidana adat masih dibutuhkan di Indonesia dengan mengaitkan konsep keadilan restorative, diskresi, dan teori pemidanaan gabungan sehingga sanksi adat yang dapat dijatuhkan adalah denda untuk upacara pembersihan.