bluuebunny/crossref_metadata_2025 huggingface dataset:
PEMERIKSAAN INDEKS MASA TUBUH, LINGKAR PERUT, KADAR GULA DARAH, ASAM URAT, KOLESTEROL DAN KONSULTASI KESEHATAN PADA LANSIA
Authors: Perwiraningtyas Pertiwi , Ka’arayeno Arie Jefry , Rosdiana Yanti
Published: November 2023

Lansia atau lanjut usia merupakan orang dengan usia diatas 60 tahun. Secara umum, lansia mengalami perubahan fungsi fisiologis organ tubuh sebagai akibat proses penuaan. Karena hal tersebut, lansia merupakan kelompok rentan berbagai penyakit, seperti diabetes mellitus, gout, dan penyakit jantung. Sehingga perlu dilakukan pemeriksaan kadar gula darah, asam urat, dan kolesterol secara rutin sebagai tindakan preventif. Tujuan kegiatan pengabdian masyarakat ini untuk membuat lansia lebih sadar untuk melakukan tindakan preventif dalam menjaga kesehatannya. Sasaran kegiatan ini adalah lansia di Desa Krobyokan Kecamatan Wagir Kabupaten Malang sebanyak 42 orang. Kegiatan dilaksanakan dalam satu hari di Posyandu lansia. Kegiatan yang dilakukan meliputi, pengukuran berat badan dan tinggi badan serta usia untuk mengetahui Indeks Massa Tubuh, Kemudian dilakukan pengukuran tekanan darh, lingkar perut, kadar gula darah, asam urat dan koleterol. Analisis dilakukan dengan deskriptif analitik. Hasil yang didapatkan, sebagian besar lansia memiliki kadar gula darah sewaktu <200mg/dL, asam urat <6mg/dL dan kolesterol <200mg/dL. Kegiatan ini sebagai upaya preventif dalam menekan morbiditas penyakit diabetes mellitus, gout, dan penyakit jantung yang terjadi pada lansia.
EDUKASI SEX EDUCATION PADA ANAK-ANAK SD
Authors: Nurmayani Winda , Halid Sopian , Syamdarniati Syamdarniati , Oktaviana Elisa
Published: November 2023

Pendidikan sex di Indonesia masih menjadi kontroversi, masih banyak anggota masyarakat yang belum menyetujui pendidikan sex di rumah maupun di sekolah. Secara umum pandangan masyarakat tentang pendidikan sex merupakan hal yang dipandang “tabu” utuk dibicarakan terhadap anak, terutama anak usia dini. Masyarakat beranggapan bahwa ada masanya mereka akan memahaminya secara alamiah. Pendidikan seks yang yang tidak diberikan di usia dini mengakibatkan tingginya kekerasan seksual pada anak yang dilakukan orang-orang terdekat anak termasuk keluarga Tujuan dari pengabdian masyarakat ini adalah memberikan pemahaman tentang sex education pada anak. Pelaksanaan kegiatan pengabdian kepada masyarakat dilakukan di SDN 46 Ampenan dengan peserta yang diambil dari kelas V dan VI. Metode yang digunakan ceramah dan Tanya jawab, dengan media yang digunakan LCD proyektor dan leaflet. Hasil dari pelaksanaan kegiatan pengabdian kepada masyarakat ini dari peserta anak-anak murid kelas V dan  VI yang hadir tampak sangat antusias, setelah kuesioner sebelum dan sesudah pemberian pendidikan kesehatan mengenai sex education  tampak adanya peningkatan pengetahuan. Pelaksanaan pemberian pendidikan kesehatan mengenai sex education untuk meningkatkan pengetahuan bagi siswa-siswa SDN 46 Ampenan dengan resiko yang mungkin bisa terjadi dengan keadaan masyarakat sangat perlu dilakukan, selain sebagai penambah dan peningkat pengetahuan juga sebagai tindak untuk mengurangi resiko terjadi pelecehan seksual terhadap anak.
PENYULUHAN DAN SIMULASI BAHAYA KEBAKARAN AKIBAT GAS DAN LISTRIK
Authors: Lestari Putri Winda , Pamungkas Vieri Ferdyhanza , Guntoro Primady , Dewanto Alfa Agie
Published: November 2023

Kebakaran menimbulkan banyak kerugian baik material maupun non-material. DKI Jakarta adalah salah satu wilayah dengan kasus kebakaran yang tinggi, baik karena korsleting listrik, gas maupun penyebab lainnya. Tujuan pengabdian masyarakat ini adalah untuk memberikan penyuluhan dan simulasi terkait bahaya kebakaran akibat gas dan listrik di Kelurahan Kebon Pala, Kecamatan Makasar, Kota Jakarta Timur. Kelompok sasaran adalah ibu rumah tangga di Kelurahan Kebon Pala sebanyak 50 orang. Metode pengabdian yaitu dengan metode penyuluhan dengan ceramah dan tanya jawab serta metode simulasi memadamkan kebakaran. Hasil diskusi menunjukkan banyak masyarakat masih panik dan takut ketika dihadapkan dengan situasi yang memungkinkan terjadinya kebakaran. Dalam kegiatan pengabdian masyarakat ini, diberikan penyuluhan tentang penyebab kebakaran, dampak kebakaran dan upaya mencegah dan menanggulangi kebakaran. Selain itu dilakukan pula simulasi memadamkan kebakaran. Kegiatan pengabdian ini mendapatkan respon positif dan dianggap bermanfaat bagi kelompok sasaran. Peserta    pengabdian    masyarakat menunjukkan antusiasme saat kegiatan dan aktif ketika diskusi maupun simulasi kebakaran.
PENINGKATAN KETERAMPILAN KELUARGA DALAM PENCEGAHAN GANGGUAN PERTUMBUHAN BATITA
Authors: Aswati Aswati , Supinganto Agus , Halid Sopian , Inayati Albayani Melati , Yolanda Henny , Nurmayani Winda
Published: November 2023

Indicators of community nutrition development through nutrition management in toddlers need to be supported by the family's ability to recognize children's growth. Having a healthy child is the hope of all families. To achieve this, of course, the family must be able to carry out family care functions which include, getting to know, making the right decisions, caring for, providing a supportive environment and utilizing existing health facilities. The purpose of this community service is to improve the ability about the function of family care in the prevention of toddler growth disorders. The outputs resulting from this community service are educational videos on preventing toddler growth disorders and the toddler growth module.
O MATERIALISMO HISTÓRICO-GEOGRÁFICO:
Authors: Branquinho Evânio dos Santos
Published: November 2023

Desde o final da década de 1960, o marxismo e a Geografia passaram por intensos debates e reformulações. A Geografia crítica, gestada no contexto de crise do capitalismo, conflitos sociais e mobilizações urbanas desse período, desdobra-se epistemologicamente para apreender essas transformações. Por outro lado, o espaço revelou-se um elemento chave na renovação do marxismo e da teoria crítica. Entretanto, a articulação geografia e marxismo colocou desafios teórico-metodológicos consideráveis, que possibilitaram a transformação de ambos, abrindo novas perspectivas, não isentas de contradições. O objetivo principal desta pesquisa é abordar o direcionamento da Geografia ao marxismo especialmente a partir da década de 1970, discutindo os principais apontamentos teórico metodológicos tratados pela disciplina, por meio de obras que fundamentaram esse encaminhamento. Metodologicamente, trata-se de uma pesquisa qualitativa, apoiada essencialmente em pesquisa bibliográfica, na discussão de obras que conceberam uma posição crítica e original sobre o conhecimento geográfico e contribuíram na reformulação de seus paradigmas.
AVALIAÇÃO DA PRODUÇÃO BIBLIOGRÁFICA DA CLIMATOLOGIA BRASILEIRA NO PERÍODO DE 1980-2020
Authors: Ribeiro Linamara Roberta , Santos Bruno César dos , Souza Paulo Henrique de
Published: November 2023

A produção da climatologia no mundo é ditada pelo ritmo das descobertas cientificas que ampliam as pesquisas e apresentam novos desafios aos estudiosos, assim como pela interferência dos eventos climáticos nas ações da população de forma direta e indireta, ou pela repercussão que alcançam junto à sociedade. O objetivo desse trabalho foi realizar um levantamento das produções bibliográficas no Brasil por meio do Portal de Periódicos da Capes, na área de Climatologia. Para isso, foram utilizadas bases indexadoras como a Science Direct, Scopus e SciELO, pesquisando termos específicos da área entre 1980-2020. Por fim com os resultados foi possível identificar de forma qualitativa e quantitativa o perfil da produção dos estudos climatológicos no Brasil. Em todas as temáticas foi possível observar um crescimento das publicações nos periódicos a partir de 2010, principalmente 2018 e 2020, podendo concluir que os últimos 10 anos estudados apresentam os maiores números de trabalhos publicados.
NOSSOS RIOS, NOSSA GENTE:
Authors: Souza Marta Maria Pereira de , Domênicis Neto João Batista de , Paula Júnior José Benedito de , Pereira Cleide Maria Ferreira
Published: November 2023

Este trabalho de Educação Ambiental foi desenvolvido nas Escolas Municipais João Luiz Pereira e Benedito Queiroz da Silva em Aparecida do Taboado/MS e na Escola Adventista de Fernandópolis/SP. A ênfase foi dada aos recursos hídricos, respectivamente córregos Santafézinha, Campo e Rondinha em Aparecida do Taboado e Engenho em Fernandópolis. Foram feitas visitas aos córregos com o intuito de observar os impactos ambientais e proceder coletas para análise da qualidade da água em sala de aula. Parcerias foram estabelecidas com o poder público e iniciativa privada em eventos como o Dia Mundial da Água, Semana do Meio Ambiente e Dia da Árvore, assim como visitas técnicas à Usina Hidrelétrica, Estação de Tratamento de Esgoto e Estação de Tratamento de Água. No desdobramento da iniciativa, uma ação de recuperação das margens dos córregos e estímulo ao uso racional da água foi desenvolvida com o título “Preservando a Água, Garantindo a Vida”.
AGRICULTURA ORGÂNICA EM ASSENTAMENTOS RURAIS:
Authors: Lindner Michele , Medeiros Rosa Maria Vieira
Published: November 2023

A produção de alimentos orgânicos em assentamentos rurais na Região Metropolitana de Porto Alegre (RMPA), no estado do Rio Grande do Sul, tem crescido nas últimas décadas. Entre eles, destaca-se a produção de arroz, pois trata-se de uma experiência inovadora, tanto em termos tecnológicos quanto nas dimensões socioeconômica, cultural e ambiental. Nesse contexto, o artigo aborda, a partir de dados secundários e de informações primárias, elementos da implantação da produção de alimentos orgânicos, em especial a de arroz orgânico, nos assentamentos da RMPA. As informações apresentadas demonstram a importância das estratégias organizacionais dos assentados no desenvolvimento e na consolidação desta produção, que se apresenta como a maior produção de arroz orgânico da América Latina.
A GEOGRAFIA NA EDUCAÇÃO INFANTIL:
Authors: Azevedo Sandra de Castro de , Silva Vitor Donizete da
Published: November 2023

A Geografia Escolar possui como um dos seus principais objetivos contribuir para que os estudantes desenvolvam por meio da abordagem dos seus conteúdos, um olhar geográfico compreendendo como suas práticas socioespaciais produzem o espaço e como eles enquanto produtores do espaço podem lutar por transformações. Para conseguirmos esse objetivo, é necessário que a geografia seja abordada com as crianças desde a Educação Infantil, dentro deste contexto, esta pesquisa realizou uma análise documental do Referencial Curricular Nacional da Educação Infantil e da Base Nacional Comum Curricular da Educação Infantil, documentos oficiais de períodos diferentes, que normatizaram os objetivos e conteúdos que devem ser desenvolvidos na educação infantil. Esta análise reforçou que existem nestes documentos possibilidades para trabalhar a geografia na educação infantil, mas para que isso ocorra é necessário pensar nas condições de trabalho do professor, em sua formação e em sua autonomia.
PROCESSO HISTÓRICO E TRANSFORMAÇÕES SOCIOESPACIAIS NO MUNICÍPIO DE ALFENAS-MG:
Authors: Costa Tamyris Maria Moreira da , Vale Ana Rute do
Published: November 2023

Desde o início de sua formação, o município de Alfenas-MG passou por transformações que afetaram seu dinamismo demográfico e socioeconômico. A partir da década de 1960, com a inundação de parte de suas terras pelas águas do lago, resultante da implantação da usina hidrelétrica de Furnas, houve a modificação da dinâmica de 34 municípios da mesorregião Sul/Sudoeste de Minas. A consolidação da cafeicultura foi o marco dessa mudança como principal atividade econômica logo após perda das várzeas férteis ocupadas pela produção de arroz. Aliada a essa nova lógica produtiva, o êxodo rural contribuiu para mudanças na infraestrutura do espaço urbano de maneira socioeconômica e cultural. Para seu desenvolvimento, esse trabalho contou com revisão bibliográfica, pesquisa documental e dados estatísticos. O processo histórico mostrou que essas transformações estreitaram a relação campo-cidade num município que, apesar da intensa urbanização, a cafeicultura mantém um papel fundamental, entretanto, com ênfase no agronegócio.
AS COOPERATIVAS NO PROCESSO DE MUNDIALIZAÇÃO DA AGRICULTURA:
Authors: Lemos Thais de Cássia Silva , Alves Flamarion Dutra
Published: November 2023

As políticas e estratégias para a modernização e exportação de commodities beneficiaram as multinacionais, que monopolizam o território rural, criando dinâmicas de produção para cada região do país. Entre as produções de commodities está o café, que passou por diversas transformações desde sua implementação no país, com histórico importante para a economia nacional, sendo a região do Sul de Minas Gerais a principal produtora. A região possui diversas multinacionais, cooperativas comerciais, que monopolizam o território para atender o capital. Dentre elas está a COOPFAM, em Poço Fundo-MG, que mesmo inserida em um modelo que valoriza os produtores familiares, contribui para o fortalecimento da monopolização cafeeira na região pelo seu importante papel para a comercialização e, assim, para o acúmulo de capital, que beneficia não somente a economia nacional, como a comercialização internacional.
TENDÊNCIAS DAS TAXAS DE SUICÍDIO NAS MICRORREGIÕES DO SUL/SUDOESTE DE MINAS GERAIS, 2000 A 2020
Authors: Bando Daniel Hideki , Souza Francisco Donizete de , Pisani Rodrigo José
Published: November 2023

Neste artigo avaliamos as tendências das taxas de suicídio nas 10 microrregiões que compõem a mesorregião Sul/Sudoeste de Minas Gerais, de 2000 a 2020. Foram calculadas as taxas de suicídio ajustadas por idade pelo método direto. A análise de tendência foi realizada com o cálculo das Variações Percentuais Anuais (VPA) das taxas de suicídio com Intervalo de Confiança de 95%. Foi utilizado o método de regressão linear logarítmica segmentada. Sete microrregiões apresentaram tendência de aumento: Itajubá (VPA=6,74), São Lourenço (VPA=4,15), Passos (VPA=3,76), Alfenas (VPA=2,97), Varginha (VPA=2,58), Poços de Caldas (VPA=1,83), São Sebastião do Paraíso (VPA=1,69). Três microrregiões apresentaram estabilidade: Pouso Alegre, Santa Rita do Sapucaí, Andrelândia. O enforcamento foi o principal meio utilizado e tem aumentado. Suicídio por intoxicação e arma de fogo apresentaram diminuição. Em 70% das microrregiões houve tendência de aumento das taxas de suicídio, 30% apresentaram estabilidade e nenhuma área apresentou tendência de diminuição.
Social Affects Engineering and Ethics
Authors: Brito Marcilio de
Published: November 2023

This text proposes a multidisciplinary reflection on the subject of ethics, based on philosophical approaches, using Spinoza’s work, Ethics, as a foundation. The power of Spinoza’s geometric reasoning and deterministic logic, compatible with formal grammars and programming languages, provides a favorable framework for this purpose. In an information society characterized by an abundance of data and a diversity of perspectives, complex thinking is an essential tool for developing an ethical construct that can deal with the uncertainty and contradictions in the field. Acknowledging the natural complexity of ethics in interpersonal relationships, the use of AI techniques appears unavoidable. Artificial intelligence in KOS offers the potential for processing complex questions through the formal modeling of concepts in ethical discourse. By formalizing problems, we hope to unleash the potential of ethical analysis; by addressing complexity analysis, we propose a mechanism for understanding problems and empowering solutions.
The Mediating Role of Adherence to Treatment in the Relationship between Interoceptive Awareness and Quality of Life in Patients with Diabetes
Authors: Hosseini Seyyed Mohammadreza , Makvandi Behnam , Sevari Karim , Bakhtiarpour Saeed
Published: November 2023

Background: Diabetes is a costly chronic condition with serious health risks like blindness, advanced renal failure, and amputation. Objectives: The present study aimed to evaluate the mediating role of adherence to treatment in the relationship between interoceptive awareness and quality of life (QoL) in patients with diabetes. Methods: This descriptive-correlational study used the structural equation modeling (SEM) technique to analyze the relationships of variables in all patients with diabetes visiting health centers of Ahvaz, Khuzestan Province (Iran) in 2022. A total of 232 patients with diabetes were selected through convenience sampling and filled out the Diabetes Quality of Life–Brief Clinical Inventory, Multidimensional Interoceptive Awareness Scale, and Morisky Medication Adherence Scale. The SEM technique was adopted to evaluate the proposed model. The results were analyzed using SPSS 27 and AMOS-25 software. Results: There was a significant relationship between adherence to treatment and QoL (β = 0.19, P = 0.003), but interoceptive awareness and QoL had no significant relationship. There was a significant relationship between interoceptive awareness and adherence to treatment (β = 0.24, P = 0.001). There was also a significant relationship between interoceptive awareness and QoL mediated by adherence to treatment in patients with diabetes (β = 0.27, P = 0.024). According to the findings, the final research model fitted well (CFI = 0.96, RMSEA = 0.076). Conclusions: Based on the results, there was a relationship between adherence to treatment and QoL in patients with diabetes. Consequently, the final model had a good fit and proved effective in improving QoL in patients with diabetes.
Effect of Pretreatment Time with Enhancers on Caffeine Skin Permeability in Rats
Authors: Mohammad Soleymani Saeed , Salimi Anayatollah , Kalantari Heibatullah , Sheykhi Adel
Published: November 2023

Background: Caffeine is an edible chemical compound obtained from various plants, such as tea and coffee. Caffeine is an alkaloid that is highly hydrophilic and has limited skin permeability. The lipophilic nature of the stratum corneum is a major barrier to the passage of this substance through the skin. Topical drug delivery systems can effectively transfer caffeine to the skin. Objectives: This study investigated the effect of pretreatment time with chemical enhancers on caffeine's skin permeation. Methods: The skin was subjected to additives such as sodium lauryl sulfate, sodium lauryl ethyl sulfate, tynoline, nanoxinol, and lecithin for 5, 15, and 30 minutes. Then, the parameters of caffeine permeability and structural changes in the skin due to additive adsorption were studied using Fourier Transform Infrared (FT-IR) spectrometry. Results: The enhancers increased the permeation of caffeine through the skin. There are different mechanisms for penetration enhancers, including lipid liquefaction, disruption of lipid bilayers, and irreversible denaturation of intracellular keratin. Conclusions: Sodium lauryl sulfate can affect the skin permeability of caffeine.
Asuhan kebidanan Pada Ny. "N" Pada Ibu 2 Jam Post Partum dengan Preeklamsia di RS Amelia Pare Kediri Tahun 2022
Authors: Luqmanasari Endah , Yusriani Markus Jelita
Published: November 2023

The puerperium period or also known as the puerperium period is a period when the reproductive organs slowly undergo changes like the state before pregnancy (Maritalia, 2014). In the puerperium, it is quite important for health workers to always monitor, especially related to complications of pre-eclampsia and eclampsia. It is a disease caused by pregnancy. The purpose of this case study is to provide Obstetric care to Mrs." N" with preeclampsia of the Puerperium period. The research design used is a case study with research subjects in Ny. "N" . Data collection methods through interviews, observation and documentation studies. The results of midwifery care in Mrs." N" obtained data on the puerperium of the mother experiencing mild preeclampsia. The problem experienced by the mother is high blood pressure. Problem management has been given according to the diagnosis and advice of the doctor. Midwifery care can increase the effectiveness of health care in mothers as a whole so that it does not endanger the mother and increase patient satisfaction in obtaining midwifery services.
Tingkat Kerawanan Demam Berdarah Dengue Berdasarkan Indeks Kerawanan Penyakit Di Kabupaten Kepahiang Provinsi Bengkulu
Authors: Denis Rica
Published: November 2023

Penyakit Demam Berdarah Dengue (DBD) disebabkan oleh virus dengue yang ditularkan oleh nyamuk Aedes aegypti. DBD dapat menyebabkan kematian jika tidak ditangani secara cepat dan tepat. Di kabupaten Kepahiang provinsi Bengkulu, angka kejadian DBD cenderung meningkat dalam 5 tahun terakhir ini. Angka kejadian ini akan mempengaruhi derajat kesehatan dan indeks pembangunan kesehatan masyarakat di kabupaten Kepahiang. Penelitian ini bertujuan untuk mengetahui tingkat kerawanan penyakit DBD di kabupaten Kepahiang berdasarkan indeks kerawanan penyakit. Metode yang digunakan dalam penelitian ini adalah metode pendekatan perhitungan Indeks Pembangunan Desa oleh BAPPENAS. Indeks kerawanan penyakit berbasis lingkungan disusun menjadi 7 dimensi yaitu pelayanan kesehatan, tenaga kesehatan, kesehatan lingkungan, kependudukan, perilaku masyarakat, pengendalian penyakit dan pemerintah yang disusun menjadi 23 indikator. Indeks kerawanan DBD tingkat Kabupaten adalah 2,771 dan termasuk pada kategori potensi rawan. Jika kondisi ini dibiarkan saja dan  tidak ada langkah pencegahan yang signifikan maka di tahun yang akan datang akan dimungkinkan untuk meningkat menjadi kategori rawan. Indeks kerawanan tertinggi di kecamatan Seberang Musi sebesar 3,348 dan terendah di kecamatan Kepahiang sebesar 2,304. Kesimpulan dari penelitian ini adalah tingkat kerawanan pada semua kecamatan di Kabupaten Kepahiang berada pada kategori potensi rawan.
Implementasi Pada Kehamilan Dengan Hipertensi Kronis Superimposed Preeklampsia
Authors: Nuraisya Wahyu
Published: November 2023

Preeclampsia is a disorder that occurs in pregnant women and is a leading cause of maternal and perinatal mortality and morbidity up to fivefold after bleeding and infection. The research approach / design that has been carried out is a case study. Research has been conducted to determine the proper implementation of Mrs. J pregnant women at UPTD Puskesmas Plosoklaten Kediri Regency. The method of data collection that has been carried out is by means of anamnesis / interview, observation and documentation (SOAP). The review and implementation will be carried out in January 2023 in the MCH room. The results of the data collection of mothers complained of frequent dizziness, had a history of hypertension from biological mothers and currently Mrs.J suffers from chronic hypertension. History of previous childbirth by means of Sectio Caesarea (SC). Blood Pressure Results 140/80 mmHg, TD tilted: 120/60 mmHg, ROT 20 (positive), MAP 100 (positive), lila 23 cm and KSPR 18 (pregnant, SC, hypertension, distance between children 2 years). On the lower extremities there is oedema of the right and left legs. Fetal Heart Rate auscultation examination is 144 x / m, regular, strong. Based on the results of subjective data and objective data, analysis. Mrs. J is G2P1A0 gestational age 23-24 weeks single/live/intrauterine fetus, KU mother and fetus are both with chronic hypertension superimposed preeclampsia. The implementation given to Mrs. J G2P1A0 UK 23-24 weeks with chronic hypertension superimposed preeclampsia was carried out comprehensively and SOP for pregnancy check. Midwives have conducted initial screening and advised patients to check with doctors for therapy and make planned early referrals to prevent complications in mothers and babies.
Hubungan Trombosit Dan Hematokrit Dengan Kejadian DBD Di Rumah Sakit Tiara Sella Kota Bengkulu Tahun 2022
Authors: Rianti Elfa , Metasari Des , Surahman S Fery
Published: November 2023

Tujuan penelitian ini diketahuinya hubungan trombosit dan hematokrit dengan kejadian Demam Berdarah Dengue Di Rumah Sakit Tiara Sella Kota Bengkulu Tahun 2022. Penelitian ini menggunakan metode kuantitatif dengan rancangan penelitian cross sectional. Populasi yang telah di teliti adalah seluruh pasien yang melakukan pemeriksan di Rumah Sakit Tiara Sella Kota Bengkulu dari Januari sampai dengan Mei Tahun 2022 yang berjumlah 3.579 Orang. Sampel penelitian ini sebanyak 97 responden. Teknik pengambilan sampel menggunakan accidental sampling. Accidental Sampling Hasil penelitian ini menunjukan ada hubungan antara trombosit dengan kejadian Demam Berdarah Dengue di rumah sakit Tiara Sella Kota Bengkulu Tahun 2022, dengan nilai asymp.sig (p)=0,004. Ada hubungan antara hematokrit dengan kejadian Demam Berdarah Dengue di rumah sakit Tiara Sella Kota Bengkulu Tahun 2022, dengan nilai asymp.sig (p)=0,019. Saran agar dinas kesehatan terkait agar dapat memberikan sosialisasi kepada masyarakat mengenai tanda-tanda penyakit DBD sehingga masyarakat paham dan cepat tanggap menangani penyakit DBD dan penanganan awal sebelum masuk kerumah sakit.
PENGARUH PENDIDIKAN KESEHATAN TERHADAP PENINGKATAN PENGETAHUAN REMAJA TENTANG PENYAKIT HIV/AIDS DI SMKS X JAKARTA
Authors: Nurlindawati  , Kustia Anggereni  , Djimmy Heru Purnomo Babo  , Tri Yunita
Published: November 2023

Usia remaja merupakan usia produktif yang sangat rentan tertular HIV-AIDS, karena saat remaja mengalami dorongan seksual yang tinggi serta selalu mencari informasi tentang seks, dan pengetahuan dan informasi yang berkaitan dengan kesehatan reproduksi yang didapatkannya sangatlah kurang. Remaja umunya lebih memilih untuk mencari berbagai sumber informasi yang dapat mereka peroleh, seperti, mengakses situs dewasa di internet, percobaan masturbasi, bercumbu atau bahkan bersenggaman dengan pacarnya. Pendidikan kesehatan sangat berperan penting dalam peningkatan pengetahuan dan sikap remaja terhadap pencegahan HIV-AIDS. Tujuan  penelitian  ini untuk mengetahui pengaruh pendidikan kesehatan terhadap peningkatan pengetahuan remaja tentang HIV/AIDS. Jenis penelitian yang digunakan kualitatif dengan rancangan pra eksperimen dengan one group pretest posttest. Hasil penelitian ini bahwa terdapat pengaruh pendidikan kesehatan terhadap peningkatan pengetahuan remaja tentang HIV/AIDS pada siswa kelas XII SMKS X Jakarta dengan hasil uji chi-square didapatkan p-value = 0,000.
ELASTIC-PLASTIC BENDING OF A RECTANGULAR BEAM
Authors: Sazairov Amirkhan
Published: November 2023

PhD. in phy. and math.sc., ass.prof., department of Mechanics, sazairov_emirxan@mail.ru Аnnotations. The article under review examines the stress-strain state of a rectangular beam, referred to a support with hinges at both ends, in flat bending under elastoplastic deformations. As a result, a differential equation for the bent axis of the beam was obtained and solved. Keywords: elastic-plastic deformation, elastic bending, yield strength
TECHNOLOGICAL PROBLEMS OF CONTAINERIZATION IN THE TRANSPORT SECTOR
Authors: Hamidov Namiq
Published: November 2023

Abstract: The author of the article addresses the topic of container cargo transportation, which is actively used in different parts of the world for the transportation of goods by all types of transport. Container cargo transportation has become an integral part of any large logistics company, since the delivery of this type of goods allows you to solve a wide range of problems. Containers ensure the safety of service personnel during increment work at ports and transfer bases, and also ensure the safety of cargo regardless of weather conditions and possible force majeure situations. This article has developed an analytical review of the problems of container transportation and proposed possible ways to solve them. The statistical data of the volume of container transfers for 2013-2023 were analyzed, the main advantages of containerization of cargo were given, and the classification of container types depending on their purpose was established.
MAIN DIRECTIONS OF MODERN TAX POLICY
Authors: Mustafayev Rashad
Published: November 2023

Summary. The purpose of the study - The role of tax policy in the formation of state budget revenues and analysis of the main directions of modern tax policy. Applied significance of the research - Creating a reliable method of tax planning is one of the ways to improve the budgeting process. Tax policy also covers the necessary issues of taxes and payments in accordance with the provisions of the legislative documents. In this regard, ensuring budget stability requires the creation of an efficient tax policy. Tax regulation acts as a key component of the success of the financial activity of a business entity. Its main purpose includes issues such as using tax benefits and advantages, minimizing tax payments by legal methods based on the correct selection of tax regimes and taxation objects, and literacy on the formation and use of accounting policy elements. Modern tax policy is reflected in the variety of applied tax types, tax rates, the creation of the circle of taxpayers and taxation objects, and the application of tax concessions.
A review of the Ptocasius Simon, 1885 spiders of Gaoligong Mountains, China (Araneae: Salticidae)
Authors: Yang Su-Fang , Peng Xian-Jin
Published: November 2023

Sixteen new species of the genus Ptocasius are described from Mt. Gaoligong, Yunnan: P. angulatus sp. nov. (♀); P. circulus sp. nov. (♀); P. danzhu sp. nov. (♂♀); P. davidi sp. nov. (♀); P. filiformus sp. nov. (♂♀); P. foliolatus sp. nov. (♀); P. geminus sp. nov. (♂♀); P. jietouensis sp. nov. (♂♀); P. longapophysis sp. nov. (♂♀); P. longlingensis sp. nov. (♂♀); P. rectangulus sp. nov. (♀); P. robustus sp. nov. (♀); P. tengchongensis sp. nov. (♂♀); P. umbellulatus sp. nov. (♀); P. zabkai sp. nov. (♂♀) and P. zonatus sp. nov. (♀). Including P. montanus (Żabka, 1981) and P. pseudoflexus (Liu, Yang & Peng, 2016), a total of eighteen species of Ptocasius have been reported from Mt. Gaoligong. For each new species, a morphological description, photos of the body and copulatory organs, line drawings of copulatory organs, and locality maps are provided.
Posterior vertebrodesis and Ponte osteotomies in surgical treatment of adolescent idiopathic scoliosis type Lenke 1-4
Authors: Ivanov Adelin
Published: November 2023

The purpose of the study is to present the results of the application of posterior vertebrodesis with Ponte osteotomies (PO) in the operative treatment of adolescent idiopathic scoliosis /AIS/, Lenke 1-4. The study encompasses patients with more than 60 degrees Cobb angle rigid deformities in the frontal plane with correction below 40% percents in the bending tests. Patients with both hyperkyphosis reported in the T5-T12 segment and marked hypokyphosis in the same area of the thoracic zone were also included in the study.

Material and methods

The study encompasses 38 patients (men 11, women 27) with adolescent idiopathic scoliosis type Lenke 1-4 and has been conducted in the period 2010-2018 The patients, included in the study, were of the age between 10 and 18 years, average age: 14.2±0.5.

Results

The following results were reported: Correction at one level osteotomy - 8-11 degrees in kyphosis and less than 5 degrees in the coronal plane; Blood loss at one level osteotomy: 50-95 ml; Time for osteotomy at one level:19-28 min.

Conclusion

Ponte osteotomy and posterior instrumentation with pedicle screws is an effective and relatively safe surgical method to achieve good sagittal and frontal correction in cases with pronounced and rigid thoracic deformities. The performance of osteotomies is associated with increased blood loss and operative time, but it is of key importance in achieving an important correction of the sagittal disorder in hyper or hypokyphosis cases.
Fingertip traumatic amputations in children. Treatment with semiocclusive foil dressings-preliminary results
Authors: Trizlov Dimitar , Raykov Dimitar , Ivanov Stoyan , Trizlov Ivan
Published: November 2023

Introduction: Traumatic fingertip amputations in childhood constitute 2% of all hand injuries in individuals under the age of 14. These injuries have a significant impact on the psychological and emotional well-being of both the children and their parents. The treatment is multifactorial, dependent on the severity and location of the injury, and can involve both conservative and surgical approaches.

Materials and Methods: The study involved 6 patients between the ages of 8 and 15 with fingertip amputations of the hand. The average duration of treatment with semi-occlusive dressings was between 3-4 weeks. The dressing was changed once a week, and after the final dressing, the border between the wound surface and healthy skin was treated with epithelializing ointments.

Results: The average duration of treatment was 20-30 days. On average, dressings were changed 3-5 times throughout the treatment period. After the completion of treatment, the pulp had a normal shape, and the cosmetic outcome was excellent. No contractures were observed in the adjacent joints, and the two-point discrimination test had an average value of 2.5 mm.

Discussion: Fingertip amputations present challenging injuries with multiple available treatment strategies. The presented technique is relatively simple to apply, reduces pain and discomfort, and allows direct visualization of the wound surface without the need for frequent dressing changes. Treatment with semi-occlusive dressings is a minimally invasive method, particularly suitable for the pediatric age group.

Conclusion: Treatment of fingertip amputations with semi-occlusive foil dressings offers several advantages in childhood. Regular patient follow-up and cooperation from both the child and the parents are essential prerequisites for successful treatment.
Impact Of The Free Trade Agreement (FTA) on Agricultural Product Export Enterprises in Vietnam
Authors: Tran Trang Mai , Nguyen Anh Viet
Published: November 2023

Signing and implementing FTAs, especially new-generation FTAs, has promoted economic growth and improved Vietnamese society's spiritual and material life. Agricultural products are one of the industries most affected by implementing new-generation FTAs. Those impacts include both positive and negative results. This paper will analyze some of the effects of the EU Free Trade Agreement (EVFTA) on agricultural export enterprises in Vietnam after signing the Agreement. From that impact analysis, the paper will offer several recommendations and solutions for businesses and the government to help agricultural export enterprises in Vietnam take full advantage and benefit, also limit the negative impacts of FTAs.
How E-Learning and Growth Mindset Determine Workforce Agility
Authors: Harumi Raisa Christia , Darmo Ika Suhartanti
Published: November 2023

The primary aim of this research project is to assess the degree to which e-learning and a growth mindset impact workforce agility within Insurance Company XYZ. A qualitative methodology was employed to accomplish this goal, which involved conducting interviews and making observations to gather data and insights on potential challenges. As part of the study, five employees from the company were interviewed by the research team. The results of the research revealed a combination of positive and negative effects. Specifically, the findings indicate that e-learning and a growth mindset have a concrete influence on employee agility. Consequently, it is strongly recommended that the company prioritize empowering, motivating, and supporting its employees to help them perform optimally and remain resilient in their work environment.
The Influence of Training and Work Motivation on Employee Performance Through Work Discipline as an Intervening Variable
Authors: Dwigita Elvina , Muslikh Muslikh
Published: November 2023

This study examines how training and work motivation impact employee performance, with work discipline as a mediator. Data was collected through questionnaires distributed to respondents using Non-probability Sampling with a purposive sampling technique. The survey collected data from 110 employees at the Human Resources Bureau of Kementerian PPN/Bappenas from March to April 2023. Structural Equation Modeling (SEM-PLS) was used for data analysis, with SmartPLS 3.0 software used for measurement model testing (outer model), structural model testing (inner model), and hypothesis testing. The results showed that education and training positively and significantly impacted work discipline. In contrast, training did not significantly affect employee performance. Work motivation positively and significantly impacted both work discipline and employee performance. Additionally, work discipline mediated the relationship between education and training and employee performance and the influence of work motivation on employee performance. This research can help agencies improve employee performance by providing insights and recommendations.
ROLE OF CLIP DOMAIN SERINE PROTEINASE 2, PmClipSP2, IN ACTIVATION OF PROPHENOLOXIDASE-ACTIVATING SYSTEM IN THE BLACK TIGER SHRIMP Penaeus monodon
Authors:   , Khorattanakulchai Narach
Published: November 2023

Clip domain serine proteinases (ClipSPs) play an important role in the prophenoloxidase-activating (proPO) system. In the shrimp Penaeus monodon, the ClipSP, PmClipSP2, has been previously shown to bind to microbial polysaccharides (LPS and β-1,3-glucan) and likely activates the proPO-system. Moreover, it may play key role in the hemocyte homeostasis by scavenging and neutralizing LPS. To reveal the binding site of the PmClipSP2 protein, the N-terminal clip domain (Clip-PmClipSP) and C-terminal SP domain (SP-PmClipSP2) were separately cloned. The recombinant proteins were then assayed for their binding properties and involvement in proPO activation, antimicrobial activity and LPS neutralization. According to the ELISA-based binding assay, rSP-PmClipSP2, but not rClip-PmClipSP, can bind immobilized LPS and β-1,3-glucan as well as significantly activate PO activity. The binding site at the SP domain is proposed to have a pattern sequence (X-[PFY]-X-[AFILV]-[AFY]-[AITV]-X-[ILV]-X(5)-W-[IL]-X) that is located at the C-terminal region of the SP domain of PmClipSP2. Deletion of the pattern sequence abolished binding to LPS and β-1,3-glucan. Conversely, a recombinant protein containing the pattern sequence (rPT-PmClipSP2-TRX) had the ability to bind to cell wall components but did not exhibit antibacterial activity via radial diffusion assay at 100 µM. Furthermore, rPmClipSP2 cannot directly neutralize toxicity of LPS in S2 cells. These results confirm the function of PmClipSP2 in binding to microbial cell wall components of bacteria and fungi via the pattern sequence at the C-terminus SP domain, subsequently leading to activation of the proPO cascade.
Development of bone scaffold from in situ forming hydrogel of Thai silk fibroin and collagen
Authors:   , Apinun Jirun
Published: November 2023

This study aimed to develop bone scaffold from in situ-forming hydrogel of Thai silk fibroin (SF) and collagen. SF solution was sterilely produced and induced to form gel by oleic acid and poloxamer-188 surfactant combinations with different HLB values. Effect of different HLB values of surfactants on gelation time and physicochemical properties of induced 4 wt% SF with/without 0.1 wt% collagen was studied. Shorter gelation time could be achieved by induction with lower HLB surfactants. SF and SF blended with collagen solution displayed negative charge with added surfactant between HLB1-20. Gel fraction measurement demonstrated inverse relationship between HLB value of surfactants and SF hydrogel stability. There was a trend showing an increase in water absorption capacity of SF with collagen hydrogel induced by surfactants with higher HLB values. Rheological studies revealed an optimum HLB value of surfactants to achieve maximum gel strength. Effect of collagen on modulus of hydrogels was also demonstrated. SEM micrographs showed typical interconnected microporous morphology of all hydrogels. An increase in HLB value of surfactants and addition of collagen resulted in larger pore size with less interporous connectivity and thicker cross-linking networks. DSC study demonstrated more complete crystallization in hydrogels induced by surfactants compared with non-induced hydrogels. There was a trend indicating higher thermal stability of hydrogels with increased HLB value of surfactants. FTIR results demonstrated higher beta-sheet structure in SF hydrogel induced by higher HLB value of surfactants. The presence of collagen precluded this effect. The gelation of SF hydrogels induced by lower HLB surfactant was resulted from interaction between SF and surfactants rather than conformational change to beta-sheet. In vitro cell culture verified the biocompatibility of SF and SF blended with collagen hydrogels with a potential to induce osteogenic differentiation of encapsulated rat’s MSC. However, added collagen promoted proliferation more than differentiation and induced matrix formation. In vivo study in rat demonstrated the biocompatibility and potential of SF/collagen hydrogel as a scaffold and carrier for cell and growth factor for bone regeneration.
Effects of extracting conditions using calcium chloride-ethanol process on characteristics of Thai silk fibroin
Authors:   , Chankow Supawich
Published: November 2023

Effects of extracting conditions using calcium chloride-ethanol (Ajisawa’s reagent) and lithium bromide (LiBr) process on characteristics of Thai silk fibroin (SF) were studied using  1: 30 - 1: 10 (w/v) dissolving ratios at 50 - 80 °C. Yields of Thai SF extractions were at 63 ± 9 - 74 ± 8 %. The Thai SFs were different in their molecular structures and thermal properties although they were similar in their amino acid compositions, molecular weights, zeta potentials, and viscosities. The Thai SFs extracted with the Ajisawa’s reagent had their random coil contents increased with decreases in the dissolving ratios and increases in the dissolution temperatures. They had their thermal decomposition masses, water evaporation enthalpies, and water contents increased with the random coil contents. Thermal decomposition temperatures of the Ajisawa-derived Thai SFs were slightly higher than those of the LiBr-derived Thai SFs. Relative contents in glycine, alanine, serine, tyrosine, and valine of the Thai SFs were at 46.6 - 48.3 mol %, 29.2 - 32.1 mol %, 4.9 - 8.2 mol %, 4.5 - 5.1 mol % and 2.3 - 2.6 mol %, respectively. Weight average and number average molecular weights of the Thai SFs were at 336 - 340 kilo Daltons and 161 - 167 kilo Daltons, respectively. Heavy-chain was degraded while light-chain was preserved at 25 kilo Daltons by the two dissolution processes. As-casted Thai SF films had their β-sheet contents at 33.8 - 35.0 %. The β-sheet contents of the SF films increased to 38.9 - 40.0 % and 42.8 - 46.7 % after treated with water vapor annealing and ethanol immersion, respectively. All SF films had similar total surface energies. Water vapor annealed SF films exhibited more surface polarities than ethanol treated SF films. The water vapor annealed film fabricated from the LiBr-derived SF was detached after 48 h. Early cell attachments of NIH-3T3 mouse fibroblasts cultured on the water vapor annealed films were higher than those cultured on the ethanol treated films. Both of them had their specific growth rates and population doubling times comparable to the cells cultured on tissue culture plates and glass substrates. The preparation processes affected the molecular structures of the Thai SFs. The SF’s molecular structures further influenced other properties including biocompatibilities with cells.
Expression and bifunctional characterization of Plasmodium falciparum orotidine 5′-monophosphate decarboxylase/orotate phosphoribosyltransferase fused enzyme
Authors:   , Paojinda Patsarawadee
Published: November 2023

Fusion of the last two enzymes in the pyrimidine biosynthetic pathway in the inversed order by having a COOH-terminal orotate phosphoribosyltransferase (OPRT) and an NH2-terminal orotidine 5'-monophosphate decarboxylase (OMPDC), as OMPDC-OPRT, are described in some organisms. Here, we produced gene fusions of Plasmodium falciparum OMPDC-OPRT, and expressed as the bifunctional enzyme in Escherichia coli. The enzyme was purified to near homogeneity using affinity and anion-exchange chromatography, exhibited enzymatic activities and functioned as a dimer. The enzymatic activities, although unstable, were stabilized by its substrate and product during purification and long-term storage. Furthermore, the enzyme expressed a perfect catalytic efficiency (kcat/Km). The turnover number (kcat) was selectively enhanced up to three orders of magnitude, while the Michaelis constant (Km) was not much affected and remained at low µM levels, when compared to the enzymes in the monofunctional and in the complex forms, as published earlier. The fusion of the two enzymes, creating a “super-enzyme” with perfect catalytic power and more flexibility, reflects cryptic relationship of enzymatic reactivities and metabolic functions on molecular evolution.
Apoptosis inducing effect of peptide/protein extracts from lentinus squarrosulus mont. In human h460 lung cancer cells
Authors:   , Prateep Arisara
Published: November 2023

In searching for the novel compounds with improving efficacy and safety profile for the treatment of lung cancer, anti-cancer activity and underlying mechanism of proteins extracted from Thai edible mushroom, Lentinus squarrosulus Mont. were firstly presented in this study. Proteins from fruiting body of L. squarrosulus Mont. were isolated by precipitation with solid ammonium sulfate at 40-80% (W/V) final concentration and further purified by ion-exchange chromatography on Diethylaminoethyl (DEAE)-cellulose, and gel filtration chromatography on Sephadex G-50 or membrane filtration, respectively. The unbound protein (F1 fraction) and the bound protein eluted with 0.3 M NaCl (F4 fraction) from ion-exchange chromatography showed the highest toxicity to human lung cancer cells with 50% inhibitory concentration (IC50) approximately 22.53 ± 0.22 µg/ml and 21.15 ± 6.14 µg/ml, respectively. The attempt to further purify to homogeneity did not succeed. So proteins from F1 and F4 fractions were used for further studies. The proteins from F4 fraction induced apoptosis cell death through the reduction of anti-apoptosis proteins including Bcl-2 and Mcl-1 which regulated mitochondrial membrane as well as the reduction of c-FLIP, an inhibitor of death receptor pathway. Meanwhile, the induction of apoptosis and the alteration of apoptosis-regulating proteins were not obviously shown in lung cancer cells incubated with proteins from F1 fraction. Although 25 µg/ml of protein from F1 and F4 fraction generated oxidative stress in human lung cancer cells, their anti-cancer activity was reactive oxygen species (ROS) independent. In summary, this study provided the novel information regarding anti-cancer activity and mechanism of proteins from fruiting body of L. squarrosulus Mont. in lung cancer cells which will be beneficial for further development as anti-cancer agent.