bluuebunny/crossref_metadata_2025 huggingface dataset:
Pre-cachexia and cachexia at diagnosis of stage III non-small-cell lung carcinoma: an exploratory study comparing two consensus-based frameworks
Authors: van der Meij Barbara S. , Schoonbeek Coline P. , Smit Egbert F. , Muscaritoli Maurizio , van Leeuwen Paul A. M. , Langius Jacqueline A. E.
Published: November 2012

Despite the development of consensus-based frameworks to define cancer cachexia, the validity and usefulness of these frameworks are relatively unknown. The aim of the present study was to study the presence of pre-cachexia and cachexia in patients with stage III non-small-cell lung carcinoma (NSCLC) by using a cancer-specific framework and a general framework for cachexia, and to explore the prognostic value of pre-cachexia and cachexia. In forty patients at diagnosis of stage III NSCLC, weight loss, fat-free mass, handgrip strength, anorexia and serum biochemistry, assessed before the first chemotherapy, were used to define ‘cancer cachexia’ or ‘cachexia’. The cancer-specific framework also classified for pre-cachexia and refractory cachexia. Additionally, quality of life was assessed by the European Organisation for Research and Treatment of Cancer – Quality of Life Questionnaire C30. Groups were compared using independent t tests, ANOVA, Kaplan–Meier and Cox survival analyses. Based on the cancer-specific framework, pre-cachexia was present in nine patients (23 %) and cancer cachexia was present in seven patients (18 %). Cancer cachexia was associated with a reduced quality of life (P= 0·03) and shorter survival (hazard ratio (HR) = 2·9; P= 0·04). When using the general framework, cachexia was present in eleven patients (28 %), and was associated with a reduced quality of life (P= 0·08) and shorter survival (HR = 4·4; P= 0·001). In conclusion, pre-cachexia and cachexia are prevalent in this small population of patients at diagnosis of stage III NSCLC. For both frameworks, cachexia appears to be associated with a reduced quality of life and shorter survival. Further studies are warranted to more extensively explore the validity and prognostic value of these new frameworks in cancer patients.
Diet-induced antisecretory factor prevents intracranial hypertension in a dosage-dependent manner
Authors: Johansson Ewa , Al-Olama Mohamed , Hansson Hans-Arne , Lange Stefan , Jennische Eva
Published: November 2012

Intake of specially processed cereal (SPC) stimulates endogenous antisecretory factor (AF) activity, and SPC intake has proven to be beneficial for a number of clinical conditions. The aim of the present study was to investigate the dosage relationship between SPC intake and plasma AF activity and to further correlate achieved AF levels to a biological effect. SPC was fed to rats in concentrations of 5, 10 or 15 % for 2 weeks. A further group was fed 5 % SPC for 4 weeks. AF activity and the complement factors C3c and factor H were analysed in plasma after the feeding period. Groups of rats fed the various SPC concentrations were subjected to a standardised freezing brain injury, known to induce increases in intracranial pressure (ICP). The AF activity in plasma increased after intake of SPC, in a dosage- and time-dependent manner. The complement factors C3c and factor H increased in a time-dependent manner. Measurements of ICP in animals fed with SPC prior to the brain injury showed that the ICP was significantly lower, compared with that of injured rats fed with a standard feed, and that the change was dose and time dependent. AF activity increases, in a dosage- and time-dependent manner, after intake of SPC. The inverse relationship between ICP after a head injury and the percentage of SPC in the feed indicate that the protective effect is, to a large extent, due to AF.
“Foolishness” in Early Modern Medicine and the Concept of Intellectual Disability
Authors: Goodey C F
Published: November 2012

The texts by Paracelsus, Felix Platter and Thomas Willis under consideration here have two things in common, despite their separate historical and cultural settings. First, they describe people who seem to relate both to their own world and to the external world in problematical ways which the authors variously call stultitia, fatuitas or stupiditas: “foolishness”. My translation is intentionally imprecise and will, I hope, restrain the reader from jumping to the conclusion that it signifies any clinical concept recognizable in modern medicine; it is, rather, an algebraic x whose content needs further investigation. The second common factor is that these are precisely the texts which some commentators do indeed believe to contain “early” diagnoses of a modern concept of intellectual disability (“mental retardation”, “learning disability” etc.). This belief, of axiomatic status, presupposes that some such concept has existed across different historical periods in a more or less mutually recognizable form, and therefore that “foolishness”, in the medical writers discussed here, just is, if primitively, our “intellectual disability”. However “foolishness” needs closer examination, which I attempt to provide here.
The Spread of Malaria to Southern Europe in Antiquity: New Approaches to Old Problems
Authors: Sallares Robert , Bouwman Abigail , Anderung Cecilia
Published: November 2012

The discoveries in the late nineteenth century that malaria is caused by protozoan parasites, which are transmitted by mosquitoes, quickly led to intense speculation about its history in antiquity. The historiography of malaria has passed through three distinct phases during the last hundred years or so. The first generation of historians to consider the effects of malaria did exaggerate its significance in some respects. The argument by W H S Jones that the Greek doctrine of fevers was based on malaria was generally and rightly accepted. However, it is not surprising that his view that malaria was a major reason for the degeneration of the moral character of the ancient Greeks attracted little sympathy. The eradication of malaria from southern Europe in the 1930s and 1940s contributed to a decline of interest in the subject. Subsequently medical historians and even professional malariologists tended to minimize the historical significance of malaria. The revisionist tendencies of this second phase of research led to attempts to reassess some of the details of the evidence upon which Jones had relied. For example, Leonard Bruce-Chwatt and Julian de Zulueta rejected Jones's belief that Plasmodium falciparum, the most dangerous of the four species of human malaria, was already active in Greece in the fifth century BC. They suggested that it started to spread in southern Europe only during the time of the Roman Empire and attributed all the references to intermittent tertian fevers in Hippocratic texts dating to the fifth and fourth centuries BC to the less virulent P. vivax. Although the literature produced during this second phase of scholarship was in many ways more sophisticated, it still suffered from some of the same weaknesses; in particular, analysis proceeded in a purely qualitative manner, without any consideration of the effects of malaria on historical human populations in quantitative terms. A second weakness was a tendency to make generalizations covering the whole of Mediterranean Europe. Since many types of mosquito are incapable of transmitting malaria to humans, mosquito breeding sites do not occur everywhere, and many mosquitoes do not fly further than a few hundred yards from their breeding sites, malaria can only be really understood by micro-analyses, conducted at a very local level, of geography, hydrology, climate, competition between different species of mosquito for breeding sites, and human activities.
Between Institutional Psychiatry and Mental Health Care: Social Psychiatry in The Netherlands, 1916–2000
Authors: Oosterhuis Harry
Published: November 2012

The term “social psychiatry” became current in the Netherlands from the late 1920s. Its meaning was imprecise. In a general way, the term referred to psychiatric approaches of mental illness that focused on its social origins and backgrounds. In this broad interpretation social psychiatry was connected to the psycho-hygienic goal of preventing mental disorders, but also to epidemiological research on the distribution of mental illness among the population at large. The treatment called “active therapy”, introduced in Dutch mental asylums in the 1920s and geared towards the social rehabilitation of the mentally ill (especially through work), was also linked with social psychiatry. In a more narrow sense social psychiatry indicated what before the 1960s was usually called “after-care” and “pre-care”: forms of medical and social assistance for patients who had been discharged from the mental asylum or who had not yet been institutionalized. This article focuses on the twentieth-century development of Dutch social psychiatry in this more narrow sense, without, however, losing sight of its wider context: on the one hand institutional psychiatry for the insane and on the other the mental hygiene movement and several outpatient mental health facilities, which targeted a variety of groups with psychosocial and behavioural problems. In fact, the vacillating position of pre- and after-care services was again and again determined by developments in these adjacent psychiatric and mental health care domains. This overview is chronologically divided into three periods: the period between and during the two world wars, when psychiatric pre- and aftercare came into being; the post-Second World War era until 1982, when the Social-Psychiatric Services expanded and professionalized; and the 1980s and 1990s, when they became integrated in community mental health centres.
Psychotherapy between Medicine, Psychoanalysis, and Politics: Concepts, Practices, and Institutions in Germany, c. 1945–1992
Authors: Roelcke Volker
Published: November 2012

Looking back at almost fifty years of psychotherapy in post-war Germany, Annemarie Dührssen (1916–98), one of the grand old ladies of the discipline, proudly presented a story of success in 1994. In the immediate post-war years, between 1946 and 1950, there were already a considerable number of individuals and groups all over the country active in establishing hospitals or outpatient clinics exclusively devoted to psychosomatic medicine and psychotherapy; in 1950, the first university programme in the subject was set up in Heidelberg; in 1967, psychoanalytically oriented psychotherapy was included in the catalogue of services offered by the statutory health insurance system; and in 1970, psychosomatic medicine and psychotherapy had become obligatory subjects in the curriculum of medical students, resulting in the establishment of chairs in these areas at almost every medical faculty in West Germany.
“The Birth of a Clinic”? The IMS Dispensary in Gyantse (Tibet), 1904–1910
Authors: McKay Alex
Published: November 2012

The establishment in 1904 of a British hospital at Gyantse, in southwestern Tibet, marked the formal introduction of biomedicine into that Himalayan state. In the ensuing decades, officers of the Indian Medical Service (IMS) offered treatment to Tibetans from their Gyantse base as a part of the British imperial relationship with the Tibetan state.
Spectacle and Secrecy: Press Coverage of Conjoined Twins in 1950s Britain
Authors: Loughlin Kelly
Published: November 2012

In the early 1950s, when the National Health Service (NHS) was still in its infancy, the British public was gripped by news reports of two attempts at the surgical separation of conjoined twins. The first operation involved one-year-old twin girls from Kano, Nigeria. The twins were xiphopagus (joined at the lower sternum) and shared a liver, separation was attempted at London's Hammersmith Hospital in December 1953. One child survived. In February 1955 news broke of the birth of craniophagus twins (joined at the head) in Keighley, West Yorkshire. Separation of the month-old girls was attempted at London's University College Hospital, but neither child survived.
Anatomical Theatres and the Teaching of Anatomy in Early Modern Spain
Authors: Martínez-Vidal Àlvar , Pardo-Tomás José
Published: November 2012

The knowledge and interpretation of the practice of anatomy in the Renaissance have recently undergone a profound change. To a large extent, this is the result of new directions taken in the social and cultural history of medicine since the late 1970s. In the last decade, several important works have been published, which are undeniable evidence of this historiographical change. However, there has as yet been no attempt to produce a synthetic view of all this new work, in which there is not always agreement. Such a synthesis would undoubtedly produce an interpretation of Renaissance anatomy very different from the traditional one.
Alligation Alternate and the Composition of Medicines: Arithmetic and Medicine in Early Modern England
Authors: Bregman Alvan
Published: November 2012

Practical mathematics in the early modern period was applied to such fields as astronomy and navigation; cartography and surveying; engineering and military arts, including gunnery; and especially banking and mercantile trade. Those who have written about practical mathematics make no mention of medical applications in their surveys, although there were many cases where physicians set up as mathematical practitioners. This article examines medical applications found in practical mathematical literature up to the end of the seventeenth century in England.
Dentistry and the University of London
Authors: Gelbier Stanley
Published: November 2012

The lack of professional qualifications was felt keenly by some nineteenth-century medical and dental practitioners. In 1860, the Lancet highlighted a scheme “to avoid the operation of the Medical Act, and to enable uneducated and unprincipled men to defraud the public”. It quoted an advertisement from a daily newspaper. Mr T Vary had announced that “Doctors, Druggists, Chemists, or Dentists, who have no Medical Diploma, can hear of an easy method of obtaining one” by writing to him at Jones's Coffee House in London's Tottenham Court Road. In response to an enquiry, Vary told the Lancet that he had just come from America where a friend “had graduated … in 1857, with all the honours”. However, the latter “had to leave America without his diploma” because of a lack of money for his graduation fees, and so had asked him to pay off the debt and bring back the diploma to Europe. Vary said: “I have done so; but have been detained longer than was anticipated, and now find my friend dead”. Indicating that he did not want to lose the money which he had paid on behalf of his friend, Vary continued: “Fortunately, as is common in America, the space for the name is left blank, to allow the graduate to have it filled up to suit his fancy by some writing master”. He proposed to sell the diploma and supporting papers for £23, which, he pointed out, was “as good as if five years' labour and 1500 dollars had been given to obtain it”. Later in the same year, the Lancet stressed that the practice of buying a Continental degree of MD, without examination or residence, was clearly a “fraud upon the public … repugnant to professional honour and destructive of professional character”. It published details of a proposition sent to Mr Pound, a surgeon in Odiham, to obtain a degree “by simple purchase”. Enclosed was a printed circular: “If you wish to become a M.D. without absenting yourself from your professional duties, I can procure you the degree from a Continental University of the highest reputation, on terms more moderate than any hitherto known in this country”. The circular was accompanied by a letter addressed personally to Pound by a Dr H A Caesar, MD, FRCSI. There is no way of knowing how many doctors or dentists actually bought copies of that or similar false diplomas.
What Tuberculosis did for Modernism: The Influence of a Curative Environment on Modernist Design and Architecture
Authors: Campbell Margaret
Published: November 2012

From the mid-nineteenth to the mid-twentieth century, specialist institutions such as sanatoria and asylums were established. In these, patients could be separated and isolated from the community and provided with the control and management of specific medical conditions such as tuberculosis and lunacy. At the start of this period, tuberculosis was a disease closely associated with the rapid growth of industrialization and a poorly nourished urban working class who lived in insalubrious, overcrowded conditions. By the early twentieth century, despite attempts by reforming socialist organizations such as the Garden City movement in England or the Life Reform movement in Germany to introduce healthier housing, these conditions had changed little. As the disease was more prevalent in younger men and women of working age, the financial drain on the European economy was considerable. By this time, research and treatment of the disease had coincided with the advent of modernism. This was a cultural movement that in architecture and applied design involved the integration of form with social purpose. It also attempted to create a new classless and hygienic lifestyle with socialist values.
The Development of Municipal General Hospitals in English County Boroughs in the 1930s
Authors: Levene Alysa , Powell Martin , Stewart John
Published: November 2012

When thinking of spurs to hospital development in the first half of the last century, it would be easy to assume that the greatest watershed was provided by the 1946 National Health Service Act. In this article, however, we focus on an earlier and often overlooked piece of legislation, which had a perhaps equally significant impact on the development of hospitals in England and Wales. This was the 1929 Local Government Act, which changed both the ownership and the focus of many of the largest hospitals in the country. As Robert Pinker has observed, the act “radically altered the percentage distribution of hospital beds in the public sector”. Such observations notwithstanding, municipal medicine in the 1930s has not received the historical attention it deserves, an omission which this article seeks in part to remedy. The terms of the act in respect of hospital development were permissive, and the extent to which local authorities acted had a great effect on the way in which their municipal hospital services developed, and hence the beds and facilities available at the time of the nationalization of the health services. The reaction of local authorities to the act, however, depended partly on their own choices, and partly on constraints over which they had less control.
The Matter of Forensic Psychiatry: A Historical Enquiry
Authors: Skålevåg Svein Atle
Published: November 2012

Since antiquity, some men have not been considered accountable for their actions when they transgressed the law, and were exempted from legal penalties, or given lesser ones. Why? The rationale for legal exemption has varied over time. So have the labels assigned to such lawbreakers, and even the personnel involved in the labelling process. For centuries, settling the question of deviant mental states of relevance to the court seemed relatively unproblematic. It was thought that personal acquaintance would easily discover such states of mind and the court could then be notified. It was not until the nineteenth century that western society felt a need to regulate this problematique. As a result, or as a precondition for this process of settling the question of legal accountability, the matter came to be construed in part as a medical problem. Physicians, and later psychiatrists, came to be regarded as possessing specific knowledge in this area which qualified them to judge a person's legal accountability. Personal knowledge of the deranged defendant was supplanted by professional knowledge of sanity and insanity as the basis for authority on the matter of accountability.
A set of silver dental instruments from the New Milton Collection
Authors: Longfield-Jones G. M.
Published: November 2012

This short paper studies a set of ten silver instruments belonging to the New Milton Collection, which are believed to be dental and of Roman date. A brief history of the set is given, also a description of each instrument together with suggested name and function, based upon the accounts of dental procedures recorded in classical medical texts. In an attempt to determine the antiquity of the set, results of non-destructive tests upon two of the instruments are compared with those of metal artefacts of authenticated date. In addition, stylistic comparisions are made with ancient instruments in museum collections, and representations of instruments upon ancient stelae and in medical manuscripts.
Illness and amputation in the eighteenth century: the case of Sir James Lowther (1673–1755)
Authors: Beckett J. V.
Published: November 2012

Sir james Lowther of Whitehaven (1673–1755) suffered from gout, and eventually had his right leg amputated in 1750. He also experienced other serious illnesses. Surviving correspondence between Lowther, in London, and his Whitehaven steward, contain graphic accounts of his health, particularly the serious illness and amputation of 1750. From these letters, and a document surviving in the British Museum describing an attack of erysipelis in 1742, a short, documentary account of Lowther's medical history has been compiled. If for no other reason, he deserves to be remembered for surviving an amputation without anaesthetic, at the age of seventy-seven.
Further information on the prehistoric representations of human hands in the cave of Gargas
Authors: Hooper Alex
Published: November 2012

This paper amends and adds recent information to Paul A. Janssens' earlier article on the prehistoric paintings of human hands in the cave of Gargas, France. Possible diagnoses for the deficiencies found in many of the hand pictures, and some non-medical theories of explanation, are reviewed. It is concluded that the hands used as stencils were mutilated and that the images were deliberately placed within the cave and were not the by-products of some other activity.
The Prehistoric hand pictures at Gargas: attempts at simulation
Authors: Wildgoose Martin , Hadingham Evan , Hooper Alex
Published: November 2012

A number of experimental methods of reconstructing prehistoric hand images like those in the cave of Gargas, France, are described and assessed. The results of experiments using these methods are evaluated from the point of view of the bearing they have on our knowledge about the creation of the original pictures in the cave.
Developmental associations between traits of autism spectrum disorder and attention deficit hyperactivity disorder: a genetically informative, longitudinal twin study
Authors: Taylor M. J. , Charman T. , Robinson E. B. , Plomin R. , Happé F. , Asherson P. , Ronald A.
Published: November 2012

Background

Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD), and associated subclinical traits, regularly co-occur with one another. However, the aetiology of their co-occurrence remains poorly understood. This paper provides the first genetically informative, longitudinal analysis of the interaction between traits of ASD and ADHD, and explores their genetic and environmental overlap.

Method

Parents of approximately 5000 twin pairs completed questionnaires assessing traits of ASD and ADHD when twins were aged 8 and 12 years. Cross-lagged longitudinal modelling explored their developmental association, enabling a consideration of phenotypic-driven processes. Overlapping aetiological influences on traits at age 12 years were explored using bivariate twin modelling.

Results

Traits of ADHD at age 8 years were more strongly predictive of traits of ASD at 12 years than traits of ASD at 8 years were of traits of ADHD at 12 years. Analysis of traits by subscales assessing specific symptom domains suggested that communication difficulties were most strongly associated with traits of ADHD. Bivariate modelling suggested moderate genetic overlap on traits in males (genetic correlation = 0.41), and a modest degree of overlap in females (genetic correlation = 0.23) at age 12 years.

Conclusions

Traits of ADHD at age 8 years significantly influence traits of ASD at age 12 years, after controlling for their initial relationship at age 8 years. In particular, early ADHD traits influenced later communication difficulties. These findings demonstrate the dynamic nature of co-occurring traits across development. In addition, these findings add to a growing body of literature suggesting that traits of ASD and ADHD may arise via similar aetiological processes.
TASK COMPLEXITY, LEARNING OPPORTUNITIES, AND KOREAN EFL LEARNERS’ QUESTION DEVELOPMENT
Authors: Kim YouJin
Published: November 2012

Building on the cognitive and interactive perspectives of task research, the cognition hypothesis states that increasing task complexity promotes greater interaction and feedback and thus facilitates second language (L2) development (Robinson, 2001b, 2007a). To date, very little research has explored this claim during learner-learner interactions in English as a foreign language (EFL) classroom contexts in which a task-based syllabus is implemented. The purpose of this study was to examine the effects of task complexity on the occurrence of interaction-driven learning opportunities and question development in such a classroom context. Korean university students (N= 191) from four intact English classes were randomly assigned to one comparison group and three experimental groups with various task-complexity levels (i.e., simple, +complex, and ++complex) based on Robinson’s framework. Their interactions were audiorecorded, and occurrences of learning opportunities, operationalized as language-related episodes (LREs), were identified. Question development was identified between pretest and posttests on the basis of the learners’ stage advancement using Pienemann and Johnston’s (1987) developmental sequence. Results indicated that more complex tasks promoted a greater number of LREs and particularly led to LREs targeting developmentally advanced question structures, which result in question development.
Climatic, ecological and socioeconomic factors as predictors of Sindbis virus infections in Finland
Authors: JALAVA K. , SANE J. , OLLGREN J. , RUUHELA R. , RÄTTI O. , KURKELA S. , HELLE P. , HARTONEN S. , PIRINEN P. , VAPALAHTI O. , KUUSI M.
Published: November 2012

Mosquito-borne Sindbis virus (SINV) causes rash-arthritis syndrome in Finland. Major outbreaks with approximately 7-year cycles have caused substantial burden of illness. Forest dwelling grouse are suspected to be amplifying hosts, with the infection transmitted to humans by mosquito bites. SINV infection surveillance data for 1984–2010 were used to create a negative binomial hurdle model, with seasonality, long-term cycles, climatic, ecological and socioeconomic variables. Climatic factors during early summer and amount of snow in April described the occurrence and incidence of SINV infections. Regulated water shore and hatch-year black grouse density described the occurrence, while population working in agriculture, agricultural land (negative) and income (negative) described the incidence of the disease. The prediction for 2009 was 85 cases (95% prediction interval 2-1187), while the actual occurrence was 106. We identified novel and known risk factors. The prevention of SINV infections in regulated water areas by infected mosquito populations should be targeted.
Effects of Natural Radiation, Photosynthetically Active Radiation and Artificial Ultraviolet Radiation-B on the Chloroplast Organization and Metabolism ofPorphyra acanthophoravar.brasiliensis(Rhodophyta, Bangiales)
Authors: Bouzon Zenilda L. , Chow Fungyi , Zitta Carmen S. , dos Santos Rodrigo W. , Ouriques Luciane C. , Felix Marthiellen R. de L. , Osorio Luz K.P. , Gouveia Claudiane , Martins Roberta de Paula , Latini Alexandra , Ramlov Fernanda , Maraschin Marcelo , Schmidt Eder C.
Published: November 2012

We undertook a study ofPorphyra acanthophoravar.brasiliensisto determine its responses under ambient conditions, photosynthetically active radiation (PAR), and PAR+UVBR (ultraviolet radiation-B) treatment, focusing on changes in ultrastructure, and cytochemistry. Accordingly, control ambient samples were collected in the field, and two different treatments were performed in the laboratory. Plants were exposed to PAR at 60 μmol photons m−2s−1and PAR + UVBR at 0.35 W m−2for 3 h per day during 21 days ofin vitrocultivation. Confocal laser scanning microscopy analysis of the vegetative cells showed single stellate chloroplast in ambient and PAR samples, but in PAR+UVBR-exposed plants, the chloroplast showed alterations in the number and form of arms. Under PAR+UVBR treatment, the thylakoids of the chloroplasts were disrupted, and an increase in the number of plastoglobuli was observed, in addition to mitochondria, which appeared with irregular, disrupted morphology compared to ambient and PAR samples. After UVBR exposure, the formation of carpospores was also observed. Plants under ambient conditions, as well as those treated with PAR and PAR+UVBR, all showed different concentrations of enzymatic response, including glutathione peroxidase and reductase activity. In summary, the present study demonstrates thatP. acanthophoravar.brasiliensisshows the activation of distinct mechanisms against natural radiation, PAR and PAR+UVBR.
Current Twin Studies in Germany: Report on CoSMoS, SOEP, and ChronoS
Authors: Hahn Elisabeth , Gottschling Juliana , Spinath Frank M.
Published: November 2012

This article summarizes the status of three recent German twin studies: CoSMoS, SOEP, and ChronoS. The German twin study on Cognitive Ability, Self-Reported Motivation, and School Achievement (CoSMoS) is a three-wave longitudinal study of monozygotic and dizygotic twins reared together, and aims to investigate predictors of and influences on school performance. In the first wave of the data collection in 2005, 408 pairs of twins aged between 7 and 11 as well as their parents participated in CoSMoS. The SOEP twin study is an extended twin study, which has combined data from monozygotic and dizygotic twins reared together with additional data from full sibling pairs, mother–child, and grandparent–child dyads who participated in the German Socio-Economic Panel (GSOEP) study. The SOEP twin project comprises about 350 twin and 950 non-twin pairs aged between 17 and 70. Data were collected between 2009 and 2010, with a focus on personality traits, wellbeing, education, employment, income, living situation, life-satisfaction, and several attitudes. The aim of the Chronotype twin study (ChronoS) was to examine genetic and environmental influences on chronotype (morningness and eveningness), coping strategies, and several aspects of the previous SOEP twin project in a sample of 301 twin pairs aged between 19 and 76 years, recruited in 2010 and 2011. Part of the ChronoS twin sample also participated in the earlier SOEP twin study, representing a second wave of assessments. We briefly describe the design and contents of these three studies as well as selected recent findings.
Assessment of error in aerosol optical depth measured by AERONET due to aerosol forward scattering
Authors: Sinyuk Alexander , Holben Brent N. , Smirnov Alexander , Eck Thomas F. , Slutsker Ilya , Schafer Joel S. , Giles David M. , Sorokin Mikhail
Published: November 2012

We present an analysis of the effect of aerosol forward scattering on the accuracy of aerosol optical depth (AOD) measured by CIMEL Sun photometers. The effect is quantified in terms of AOD and solar zenith angle using radiative transfer modeling. The analysis is based on aerosol size distributions derived from multi‐year climatologies of AERONET aerosol retrievals. The study shows that the modeled error is lower than AOD calibration uncertainty (0.01) for the vast majority of AERONET level 2 observations, ∼99.53%. Only ∼0.47% of the AERONET database corresponding mostly to dust aerosol with high AOD and low solar elevations has larger biases. We also show that observations with extreme reductions in direct solar irradiance do not contribute to level 2 AOD due to low Sun photometer digital counts below a quality control cutoff threshold.
Geomagnetic and solar wind fluctuations at discrete frequencies: A case study
Authors: Villante U. , Del Corpo A. , Francia P.
Published: November 2012

A worldwide analysis of geomagnetic field measurements, during a period of wave activity following an intense magnetospheric perturbation, revealed signals at discrete frequencies (f ≈ 1.0, ≈1.9, ≈2.2–2.4, ≈2.6, ≈3.4–3.6, and ≈4.7 mHz) which are similar to the frequencies identified from auroral to low latitudes in previous investigations. All the power enhancements found correspondence in enhancements, approximately at the same frequencies, in the solar wind dynamic pressure, and/or speed and interplanetary magnetic field components. The modes dominant in the wide afternoon sector (f ≈ 1.9, ≈2.6, and ≈3.4–3.6 mHz) were almost ubiquitously detected, and rough estimates of the propagation parameters appear consistent with those expected for standing cavity modes. The modes emerging in the morning sector (f ≈ 1.0 and ≈2.2–2.4 mHz) appear related to the fluctuations of the magnetopause current, driven by those of the solar wind pressure.
Overview of a range of solution methods for elastic dislocation problems in geophysics
Authors: van Zwieten G. J. , Hanssen R. F. , Gutiérrez M. A.
Published: November 2012

Tectonic faults are commonly modeled as Volterra or Somigliana dislocations in an elastic medium. Over the years, many practical solution methods have been developed for problems of this type. This work presents a concise overview in consistent mathematical notation of the most prominent of these methods, emphasizing what the various methods have in common and in what aspects they are different. No models other than that of elastic dislocations are considered. Special attention is given to underlying assumptions and range of applicability.
Sea ice impacts on spring bloom dynamics and net primary production in the Eastern Bering Sea
Authors: Brown Zachary W. , Arrigo Kevin R.
Published: November 2012

In the Eastern Bering Sea, changes in sea ice have been implicated in recent major upper‐trophic level shifts. However, the underlying relationships between sea ice and primary producers have not been well tested. Here, we combine data from multiple satellite platforms, reanalysis model results and biophysical moorings to explore the dynamics of spring and summer primary production in relation to sea ice conditions. In the northern Bering Sea, sea ice consistently retreated in late spring, leading to ice‐edge phytoplankton blooms in cold (0–1 °C) waters. However, in the southeastern Bering Sea, sea ice retreat was far more irregular. Although this did not significantly alter bloom timing, late retreat led to blooms at the ice‐edge while early retreat led to blooms in open waters that were warmer (≤5.4 °C) and >70% more productive. Early sea ice retreat also led to higher productivity in summer, likely due to weaker thermal stratification. Overall, annual net primary production during warm years of early sea ice retreat was enhanced by 40–50% compared to years with late sea ice retreat in the southeastern Bering Sea. These findings suggest the potential for future sea ice loss to enhance overall carrying capacity of the southeastern Bering Sea ecosystem. Consistently warm blooms in the future may also channel more energy flow toward the pelagic, rather than benthic, environment. To date, however, neither sea ice extent nor the timing of its retreat have undergone long‐term changes in the Eastern Bering Sea.
Ice sheet record of recent sea‐ice behavior and polynya variability in the Amundsen Sea, West Antarctica
Authors: Criscitiello Alison S. , Das Sarah B. , Evans Matthew J. , Frey Karen E. , Conway Howard , Joughin Ian , Medley Brooke , Steig Eric J.
Published: November 2012

Our understanding of past sea‐ice variability is limited by the short length of satellite and instrumental records. Proxy records can extend these observations but require further development and validation. We compare methanesulfonic acid (MSA) and chloride (Cl–) concentrations from a new firn core from coastal West Antarctica with satellite‐derived observations of regional sea‐ice concentration (SIC) in the Amundsen Sea (AS) to evaluate spatial and temporal correlations from 2002–2010. The high accumulation rate (~39 g∙cm–2∙yr–1) provides monthly resolved records of MSA and Cl–, allowing detailed investigation of how regional SIC is recorded in the ice‐sheet stratigraphy. Over the period 2002–2010 we find that the ice‐sheet chemistry is significantly correlated with SIC variability within the AS and Pine Island Bay polynyas. Based on this result, we evaluate the use of ice‐core chemistry as a proxy for interannual polynya variability in this region, one of the largest and most persistent polynya areas in Antarctica. MSA concentrations correlate strongly with summer SIC within the polynya regions, consistent with MSA at this site being derived from marine biological productivity during the spring and summer. Cl– concentrations correlate strongly with winter SIC within the polynyas as well as some regions outside the polynyas, consistent with Cl– at this site originating primarily from winter sea‐ice formation. Spatial correlations were generally insignificant outside of the polynya areas, with some notable exceptions. Ice‐core glaciochemical records from this dynamic region thus may provide a proxy for reconstructing AS and Pine Island Bay polynya variability prior to the satellite era.
Systematic and random errors between collocated satellite ice water path observations
Authors: Eliasson S. , Holl G. , Buehler S. A. , Kuhn T. , Stengel M. , Iturbide‐Sanchez F. , Johnston M.
Published: November 2012

There remains large disagreement between ice‐water path (IWP) in observational data sets, largely because the sensors observe different parts of the ice particle size distribution. A detailed comparison of retrieved IWP from satellite observations in the Tropics (±30° latitude) in 2007 was made using collocated measurements. The radio detection and ranging(radar)/light detection and ranging (lidar) (DARDAR) IWP data set, based on combined radar/lidar measurements, is used as a reference because it provides arguably the best estimate of the total column IWP. For each data set, usable IWP dynamic ranges are inferred from this comparison. IWP retrievals based on solar reflectance measurements, in the moderate resolution imaging spectroradiometer (MODIS), advanced very high resolution radiometer–based Climate Monitoring Satellite Applications Facility (CMSAF), and Pathfinder Atmospheres‐Extended (PATMOS‐x) datasets, were found to be correlated with DARDAR over a large IWP range (~20–7000 g m‐2). The random errors of the collocated data sets have a close to lognormal distribution, and the combined random error of MODIS and DARDAR is less than a factor of 2, which also sets the upper limit for MODIS alone. In the same way, the upper limit for the random error of all considered data sets is determined. Data sets based on passive microwave measurements, microwave surface and precipitation products system (MSPPS), microwave integrated retrieval system (MiRS), and collocated microwave only (CMO), are largely correlated with DARDAR for IWP values larger than approximately 700 g m‐2. The combined uncertainty between these data sets and DARDAR in this range is slightly less MODIS‐DARDAR, but the systematic bias is nearly an order of magnitude.
Quantifying the effect of urbanization on U.S. Historical Climatology Network temperature records
Authors: Hausfather Zeke , Menne Matthew J. , Williams Claude N. , Masters Troy , Broberg Ronald , Jones David
Published: November 2012

An assessment quantifying the impact of urbanization on temperature trends from the U.S. Historical Climatology Network (USHCN) is described. Stations were first classified as urban and nonurban (rural) using four different proxy measures of urbanity. Trends from the two station types were then compared using a pairing method that controls for differences in instrument type and via spatial gridding to account for the uneven distribution of stations. The comparisons reveal systematic differences between the raw (unadjusted) urban and rural temperature trends throughout the USHCN period of record according to all four urban classifications. According to these classifications, urbanization accounts for 14–21% of the rise in unadjusted minimum temperatures since 1895 and 6–9% since 1960. The USHCN version 2 homogenization process effectively removes this urban signal such that it becomes insignificant during the last 50–80 years. In contrast, prior to 1930, only about half of the urban signal is removed. Accordingly, the National Aeronautics and Space Administration Goddard Institute for Space Studies urban‐correction procedure has essentially no impact on USHCN version 2 trends since 1930, but effectively removes the residual urban‐rural temperature trend differences for years before 1930 according to all four urban proxy classifications. Finally, an evaluation of the homogenization of USHCN temperature series using subsets of rural‐only and urban‐only reference series from the larger U.S. Cooperative Observer (Coop) Network suggests that the composition of Coop stations surrounding USHCN stations is sufficiently “rural” to limit the aliasing of urban heat island signals onto USHCN version 2 temperature trends during homogenization.
Searching at the right time of day: Evidence for aqueous minerals in Columbus crater with TES and THEMIS data
Authors: Baldridge Alice M. , Lane Melissa D. , Edwards Christopher S.
Published: November 2012

The primary objective of the Thermal Emission Imaging System (THEMIS) experiment, which has been in orbit at Mars since early 2002, is to identify minerals associated with hydrothermal and subaqueous environments. Data from THEMIS have supported the presence of clays, silica‐rich deposits, and chlorides but has not before provided definitive evidence for the presence of sulfates. This is an especially puzzling result given that sulfates have been extensively identified with other instruments at Mars. If present, sufficiently exposed, and in high enough abundances, such minerals should be detectable in orbital thermal infrared spectra at the resolution of THEMIS. The extended mission proposal for THEMIS on Mars Odyssey suggests that the detection of all minerals may be enhanced by observing at an earlier time of day and thus at warmer temperatures. Therefore, in 2009, Odyssey moved to an earlier orbit time. Here, we examine THEMIS data collected when the earlier orbit time coincided with the Martian local (southern) late summer (Ls = 270) for Columbus crater where Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) data have detected a number of aqueous minerals. Some of the warmest THEMIS images show evidence for aqueous minerals, although not in the same locations where CRISM finds the highest concentrations. Several factors contribute to this result, including differences in the diurnal temperature curve and levels of induration and particle size. For THEMIS, earlier time‐of‐day and proper seasonal observations combine to provide warm surface temperatures and ideal low atmospheric opacity that significantly increases the ability to definitively identify low spectral contrast aqueous minerals at the surface of Mars.
River channel lateral mobility: metrics, time scales, and controls
Authors: Wickert Andrew D. , Martin John M. , Tal Michal , Kim Wonsuck , Sheets Ben , Paola Chris
Published: November 2012

Alluvial river channels are intrinsically mobile. We mapped channel planform extent in a series of experiments to measure instantaneous rates of channel motion, loss of planform overlap with the original positions of the channels, and reworking of the fluvial surface over which the channels moved. These experiments comprise two aggrading deltas, one subsiding delta that underwent cyclical base level changes, and one braided channel system that was seeded with vegetation. We find that the amounts of channel planform overlap and remaining unreworked fluvial surface area both decay exponentially with time, and that these metrics and the instantaneously‐measured rates of channel motion scale predictably with one another in spite of the different time scales of the processes they record. Rates of channel planform change increase with increasing sediment flux and bed and planform irregularity, and decrease with the establishment of riparian vegetation. Aggradation does not noticeably affect channel mobility, but induces avulsions that allow the channels to more rapidly rework the fluvial surface. Additional findings include that: (1) sediment flux in the braided experiment equals its rate of bar migration, (2) channel widths are normally distributed with time, and (3) we can use our channel mobility metrics to connect surface processes with the resultant fluvial stratigraphy.
The CGILS experimental design to investigate low cloud feedbacks in general circulation models by using single‐column and large‐eddy simulation models
Authors: Zhang Minghua , Bretherton Christopher S. , Blossey Peter N. , Bony Sandrine , Brient Florent , Golaz Jean‐Christophe
Published: November 2012

A surrogate climate change is designed to investigate low cloud feedbacks in the northeastern Pacific by using Single Column Models (SCMs), Cloud Resolving Models (CRMs), and Large Eddy Simulation models (LES), as part of the CGILS study (CFMIP‐GASS Intercomparison of LES and SCM models). The constructed large‐scale forcing fields, including subsidence and advective tendencies, and their perturbations in the warmer climate are shown to compare well with conditions in General Circulation Models (GCMs), but they are free from the impact of any GCM parameterizations. The forcing fields in the control climate are also shown to resemble the mean conditions in the ECMWF‐Interim Reanalysis. Applications of the forcing fields in SCMs are presented. It is shown that the idealized design can offer considerable insight into the mechanisms of cloud feedbacks in the models. Caveats and advantages of the design are also discussed.
Household water saving: Evidence from Spain
Authors: Aisa Rosa , Larramona Gemma
Published: November 2012

This article focuses on household water use in Spain by analyzing the influence of a detailed set of factors. We find that, although the presence of both water‐saving equipment and water‐conservation habits leads to water savings, the factors that influence each are not the same. In particular, our results show that those individuals most committed to the adoption of water‐saving equipment and, at the same time, less committed to water‐conservation habits tend to have higher incomes.