bluuebunny/crossref_metadata_2025 huggingface dataset:
Extracts from an advising session: How viewpoint switching can help broaden learner perspectives and provide positive feedback
Authors: Ashton Thomas
Published: September 2021

Advising in language learning is a relatively new field that has generated considerable interest amongst educational practitioners because of its focus on the individual language learner. Advising is an effective way of generating motivation and fostering learner autonomy as it encourages reflection on the language learning process. With this in mind, adequate training must be provided for developing language learning advisors and educational practitioners making the transition from teachers to advisors. This paper contains a brief description of an advising session from a developing learning advisor who focuses on two particular advising strategies: those of broadening perspectives and giving positive feedback. The outcomes are developmental and by presenting them I aim to highlight some of the difficulties for teachers making the transition to becoming a Language Learning Advisor.
USING THE THEORY OF REASONED ACTION TO PREDICT SMOKING INTENTION AMONG NON-SMOKING SECONDARY SCHOOL GOING ADOLESCENTS IN PENINSULAR MALAYSIA
Authors: Lim Kuang Hock , Lim Hui Li , Mohd Ghazali Sumarni , Kee Chee Cheong , Tain Mohd Zainuldin , Cheong Yoon Ling , Cheah Yong Kang , Ismail Syazwan Aizat , Heng Pei Pei , Lim Jia Hui
Published: September 2021

The study aims to determine the relationship of attitude and social-norm with the intention to smoke in the future among non-smoking youth. Data were derived from a study on smoking among form four students in a selected secondary school in Peninsular Malaysia, which utilised a pre-validated questionnaire to obtain data from the selected respondents. Descriptive statistics and structural equation modelling (SEM) were used in data analysis. The study revealed independent variables accounted for 22.6% of the variance in intention to initiate smoking and the model had a good fit. A significant relationship was observed between subjective norm and intention to initiate smoking (R=0.46). The study revealed that attitude and social norm substantially explained intention to smoke among non-smoking adolescents. Future measures should concentrate on correcting the subjective norms to reduce the intention to initiate smoking among non-smoking youth.
Use of nanosystems to improve the anticancer effects of curcumin
Authors: Araya-Sibaja Andrea M , Salazar-López Norma J , Wilhelm Romero Krissia , Vega-Baudrit José R , Domínguez-Avila J Abraham , Velázquez Contreras Carlos A , Robles-Zepeda Ramón E , Navarro-Hoyos Mirtha , González-Aguilar Gustavo A
Published: September 2021

Curcumin (CUR) is a phenolic compound that is safe for human consumption. It exhibits chemopreventive, antiproliferative, antiangiogenic, and antimetastatic effects. However, these benefits can be hampered due to the lipophilic nature, rapid metabolism, low bioavailability, and fast elimination of the molecule. Considering this, the present work reviews the use of CUR-based nanosystems as anticancer agents, including conventional nanosystems (i.e., liposomes, nanoemulsions, nanocrystals, nanosuspensions, polymeric nanoparticles) and nanosystems that respond to external stimuli (i.e., magnetic nanoparticles and photodynamic therapy). Previous studies showed that the effects of CUR were improved when loaded into nanosystems as compared to the free compound, as well as synergist effects when it is co-administrated alongside with other molecules. In order to maximize the beneficial health effects of CUR, critical factors need to be strictly controlled, such as particle size, morphology, and interaction between the encapsulating material and CUR. In addition, there is an area of study to be explored in the development of CUR-based smart materials for nanomedical applications. Imaging-guided drug delivery of CUR-based nanosystems may also directly target specific cells, thereby increasing the therapeutic and chemopreventive efficacy of this versatile compound.
Synthesis of 5-arylacetylenyl-1,2,4-oxadiazoles and their transformations under superelectrophilic activation conditions
Authors: Puzanov Andrey I , Ryabukhin Dmitry S , Zalivatskaya Anna S , Zakusilo Dmitriy N , Mikson Darya S , Boyarskaya Irina A , Vasilyev Aleksander V
Published: September 2021

Acetylene derivatives of 1,2,4-oxadiazoles, i.e., 5-(2-arylethynyl)-3-aryl-1,2,4-oxadiazoles, have been obtained, for the first time reported, from 5-(2-arylethenyl)-3-aryl-1,2,4-oxadiazoles by their bromination at the carbon–carbon double bond followed by di-dehydrobromination with NaNH2 in liquid NH3. The reaction of the acetylenyl-1,2,4-oxadiazoles with arenes in neat triflic acid TfOH (CF3SO3H) at room temperature for 1 h resulted in the formation of E/Z-5-(2,2-diarylethenyl)-3-aryl-1,2,4-oxadiazoles as products of regioselective hydroarylation of the acetylene bond. The addition of TfOH to the acetylene bond of these oxadiazoles quantitatively resulted in E/Z-vinyl triflates. The reactions of the cationic intermediates have been studied by DFT calculations and the reaction mechanisms are discussed.
A Relational Theory of Organization Creation About Making: Anthropology, Archaeology, Art and Architecture by Tim Ingold (2013)
Authors: Paulus Odile
Published: September 2021

In his book Making: Anthropology, Archaeology, Art and Architecture, Tim Ingold describes human action after having studied the four fields mentioned in the title. The anthropologist recommends that researchers live with the group of people being studied. He criticizes the hylemorphic approach of human action, according to which human beings are seen to impose a preconceived form from their mind onto matter, or the material. Instead, he proposes a theory of life in society based on so-called lines of correspondence. Drawing on the cases of a prehistoric human being, a medieval craftsperson and an artist, he sees these to be experiencing, with other beings and with objects, lines of correspondence defined by attention and transformation and which are developed in a process.
Then and now: analyzing Filipino youth education and work decisions following the 12 basic education reform
Authors: Vital Marianne Joy
Published: September 2021

This research aims to analyze the trends in youth education and work outcomes before and after the implementation of the kindergarten to grade 12 (K-12) Basic Education Reform, focusing on three broad outcomes: (1) in education, (2) in employment, or (3) not in employment, education or training (NEET). It determines certain characteristics associated with each of these outcomes by employing multinomial logistic regression analysis. The study finds that although the overall likelihood of being in education has increased after the reform, certain groups, particularly disadvantaged ones, still have higher probabilities of being in employment or NEET rather than continuing their education. Furthermore, after the reform, young men from disadvantaged groups have a higher probability of being NEET. Albeit minimal, this merits investigation and monitoring in the future, as it may worsen inequalities.
La democracia en Chile. Trayectoria de Sísifo
Authors: Posada Carbó Eduardo
Published: September 2021

Reseña de La democracia en Chile. Trayectoria de Sísifo de Joaquín Fermandois
Impact of COVID-19 Pandemic on Global Healthcare Systems and the role of a new era of global collaborations
Authors: Jain Parth
Published: September 2021

The Covid-19 pandemic has changed the world, socially, economically and politically. There have been many positives in global scientific information flow, collaboration, speed of translation of research, technological innovation and its diffusion has been phenomenal.  However the cost to human lives and livelihood has also been catastrophic.

In the post-pandemic world, the ambition to provide a well-resourced and universal health infrastructure to populations has become a challenge even for wealthy nation-states. The access to routine and elective healthcare has become severely compromised. In poorer nations, this has affected basic healthcare needs particularly for children, women and those on or below the poverty line.

Yet health is a fundamental human right, one that is guaranteed by the treatise on ‘Declaration of Health for All’ to which most countries are signatories. However, could the impact of this pandemic be mitigated by global health initiatives and collaboration? In this context, it is pertinent to analyse the existing global health framework and conventions to identify how we may prepare for future challenges.
Updated Ephemeris and Evidence for a Period Change in the Eclipsing Novalike Variable 1RXS J064434.5+334451
Authors: Shafter A. W. , Bautista Vladimir
Published: September 2021

We report seven new eclipse timings for the novalike variable 1RXS J064434.5+334451. An analysis of our data, along with all previously available timings (36 published and 16 unpublished), yields a best-fitting linear ephemeris of BJDecl = 2,453,403.7611(2) + 0.269,374,43(2)E. We find a somewhat improved fit with a quadratic ephemeris given by: BJDecl = 2,453,403.7598 + 0.269,374,87 E − 2.0 × 10−11 
E
2, which suggests that the orbital period may be decreasing at a rate given by

P

˙

≃
−
1.5
×

10

−
10

.
Improvement of Barrel Weapons Interior Ballistic Model Using Dynamic Vivacity Function
Authors: Schmidt Martin , Beer Stanislav , Konečný Pavel
Published: September 2021

The paper discuses a possibility of application of the dynamic vivacity function defined in COS 137604 (STANAG 4115) at the interior ballistic process mathematical model conversion. At present time various technologies of powder grain surfacing are used mainly in case of powders used in assemblies of small-calibre cartridges. The grain surfacing can properly influence the shot process, change character of the powder grain burning which cannot be described by the burning theory according to geometrical rules. COS 137604 determines necessity of the dynamic vivacity function L evaluation for artillery powders only, but the way of its evaluation can be applied for arbitrary powder. It then allows the get results of the interior ballistic tasks solutions with higher accuracy as well as the choice of the suitable grain surfacing technology.
An Efficient Destructive Interference Based on Side Lobe Suppression Method in SONAR Beamforming
Authors: Pillai S. , Santhanakrishnan T. , Rajesh R.
Published: September 2021

A novel beamforming technique that resembles the principle of interference is proposed for sonar arrays to suppress the side lobes while the main lobe is kept intact. It uses two window functions. The first one is a rectangular function that produces a primary beam pattern. A secondary new window function is derived and its beam pattern is steered such that the null or trough of the main lobe of the new window coincides with the peak or crest of the first side lobe of the rectangular window and so on to other major side lobes. Pattern multiplication was used to get a final beam pattern. The approach is simulated and verified through a sonar array with 24 hydrophone sensors.
A new species of Homatula (Teleostei: Cobitoidea: Nemacheilidae) from the Pearl River, China
Authors: Min Rui , Yang Jun–Xing
Published: September 2021

Analyses of morphological and molecular data from specimens of Homatula from China reveal an undescribed species which lives in the Nanpanjiang River, the upper Pearl River, and indicate that H. acuticephala is a synonym of H. anguillioides. The new species is collected from Yunnan, China. It differs from its congeners by having a naked and robust body, developed adipose crests (depth of caudal peduncle in the percent of its length:70.53–78.48), a median notch on the lower jaw, a median gap on the lower lip, short barbels with maxillary barbels extend posteriorly reaching the anterior edge of eyes, vertebrae 37–38, completed lateral line. New species differs from other species of Homatula by 0.05–0.11 in K2P distance of mitochondrial cytochrome c oxidase subunit 1. Phylogenetic analysis based on mitochondrial cytochrome c oxidase subunit 1 indicate that new species formed a sister group to co-drainage species. Based on both morphological and molecular results, we confirm that the validation of this undescribed species named H. robusta sp. nov. and describe it.
La crèche familiale thérapeutique : un dispositif pour les fratries puînées d'enfants autistes
Authors: Klein Anaelle , Breil Fleur , Durieux Marie-José , Rappaport Clémentine
Published: September 2021

Il s’agit d’exposer notre cheminement de pensées et la naissance de nos interrogations autour de ces situations d’enfants autistes où la question d’une surveillance, voire d’une prise en charge des frères et sœurs puînés s’est posée. Nous présentons notre cas princeps, celui d’un garçon de 30 mois chez qui nous avons diagnostiqué un autisme infantile. Les éléments biographiques, l’histoire développementale et l’anamnèse des troubles ont été principalement recueillis grâce au récit de la mère. Trois consultations pédopsychiatriques et deux séances de psychomotricité ont permis l’élaboration du diagnostic. Durant le temps d’observation des troubles de ce jeune garçon, sa petite sœur de 4 mois a progressivement présenté des signes de souffrance qui nous ont paru inquiétants. La question de la prise en charge de celle-ci s’est donc posée. Nous soulevons la problématique du retentissement de l’autisme sur les fratries puînées à travers une étude des risques génétique, psychiatrique et psychologique. Le repérage précoce des signes prémorbides chez ces bébés considérés comme « à risque autistique » est important à connaître dans un but de prévention. Nous décrivons le dispositif de crèche familiale thérapeutique, développé au sein de la consultation pédopsychiatrique des 0-3 ans de l’hôpital d’Aulnay-sous-Bois, afin que les frères et sœurs d’enfants autistes aient des temps de soins précoces adaptés.
Autisme et prématurité : intérêt du croisement des regards pédiatrique et pédopsychiatrique. Le cas d'Arthur
Authors: Breil Fleur , da Silva Gabriel , Fillez Sylvie , Durieux Marie-José
Published: September 2021

Arthur, ancien prématuré de 27 semaines d’aménorrhées, est âgé de deux ans et demi lorsqu’il nous est adressé par son pédiatre néonatologue pour l’évaluation et la prise en charge de signes d’autisme infantile déjà bien installés. Les premières rencontres avec cet enfant permettent aussi d’évaluer la situation de précarité et d’isolement de la famille, les grandes fragilités parentales. L’histoire d’Arthur illustre bien la nécessaire collaboration multidisciplinaire qu’impose le suivi de ces enfants prématurés. L’application du protocole préaut à la cohorte des enfants prématurés par le service de néonatologie de l’hôpital d’Aulnay a renforcé la sensibilisation des équipes à l’observation des capacités relationnelles du bébé. Pédiatres et pédopsychiatres se sont dotés d’espace et de temps pour se rencontrer, échanger, croiser leurs différents regards. La confrontation de ces regards permet un repérage et une orientation précoce de ces «?bébés à risque?», elle ouvre des perspectives diversifiées dans l’accompagnement des familles et la thérapie de l’enfant.
Quelle place le droit français reconnaît-il… ? aux parents d'un enfant placé ?
Authors: Eudier Frédérique
Published: September 2021

L’article précise d’abord les principes des droits parentaux sur l’enfant. Il s’agit d’un droit fondamental, selon la Cour européenne des droits de l’homme de Strasbourg, pour un enfant de vivre avec ses parents. Sont ensuite soulignées les restrictions à ces droits parentaux avec deux possibilités que sont la délégation de l’autorité et le retrait de cette autorité parentale. La fin de l’article permet de montrer comment la France n’utiliserait pas suffisamment tous les potentiels juridiques adaptables aux situations familiales particulières.
De l'irréparable
Authors: Lefebvre Danielle , Stéphanoff Marina
Published: September 2021

Notre société fait la part belle à la notion de séparation tellement la souffrance d’autrui nous apparaît comme insupportable et, ce faisant, transforme tout sujet ayant subi un acte plus ou moins barbare de la part d’un adulte, en victime pure. Or, est-ce le bon chemin pour faire qu’il n’y ait pas répétition et que l’enfant, de position de sujet souffrant d’actes irréparables, puisse vivre sa vie d’adulte autrement qu’en « ancienne victime » réclamant sans cesse réparation. Quelle réparation ? À travers une courte vignette clinique, les auteurs montrent ainsi comment reconnaître l’irréparable, c’est aussi penser la séparation comme un acte thérapeutique qui permettra de différencier les souffrances et de les accueillir comme telles. C’est faire barrage à la répétition.
Vivre et accompagner les séparations, l'accompagnement en accueil familial
Authors: Martinez Anne-Marie
Published: September 2021

L’auteur présente les grands traits de la procédure de placement familial d’un mineur, mais surtout insiste sur la notion de contrat et la procédure d’accompagnement et de préparation indispensable pour mener à bien cette opération douloureuse. Un enfant qui arrive est un enfant qui part : cela signifie qu’il faut tenir compte de la douleur de la séparation d’un enfant vis-à-vis de ses parents, même maltraitants, mêmes auteurs de violence ou de négligence. L’enfant accueilli est un hôte de passage ; il est important d’avoir cette notion de temporalité dans la procédure, il ne s’agit pas d’un placement définitif. Et le départ vers sa famille d’origine ou dans la vie d’adulte mérite aussi un rite de départ, une fête. Ainsi, le mineur placé pourra vivre au mieux ce moment.
Guénouvry : des lieux séparés pour différencier des places
Authors: Pétry Philippe
Published: September 2021

L’entretien avec l’équipe de Guénouvry réalisé lors d’une session de formation traite d’un placement familial spécialisé adossé à un institut médico-éducatif en Bretagne. Les enfants accueillis sont pour la plupart psychotiques ou autistes. Une vigilance particulière sur la différenciation des lieux et des places constitue une condition pour qu’un travail de subjectivation soit possible pour ces jeunes, aux prises avec des troubles sévères qui entament leur possibilité de se soutenir comme sujets. La séparation physique des lieux, les interdictions de mélange ou d’intrusion permettent de maintenir des espaces réels et imaginaires que l’enfant utilise pour manifester des symptômes et des possibilités différentes selon les lieux.
La puissance par l’image
Authors: Ekman Alice
Published: September 2021

La diplomatie publique de la Chine n’a plus rien à envier à celle des pays occidentaux, au regard de sa professionnalisation, de ses outils et de son budget. Toutefois, la supervision du Parti et le recadrage disciplinaire et idéologique mené par Xi Jinping l’ont reconvertie en une ambitieuse stratégie de propagande, agressive vis-à-vis de certains pays, séductrice face à d’autres.
Fabrique de la crise et identité
Authors: Sahraouia Sabrina , Sellam Nadia , Teguia Amina
Published: September 2021

Dans l’espace démocratique, l’identification constitue une stratégie d’intégration et d’adaptation. Ainsi, il est primordial de s’interroger sur les fondements de l’identité nationale et de se questionner sur son état. Est-elle réellement en crise ? Pourquoi parle-t-on de crise ?
Adolescence : Crise !
Authors: Agraimbah Aicha , Carda Priscille , Couppey Émeline
Published: September 2021

« Je me rappelle de cette crise qu’on appelle tous « crise d’adolescence » qui a fait de moi un être monstrueux durant 3 années. Je me rappelle des nuits passées hors de la maison où je sortais en cachette et prétextais, quelques heures après, être chez une copine… » La crise d’adolescence n’est pas un passage obligé ou un rite. La relation qu’entretient la famille avec le jeune avec un refus pour certains parents de le voir s’émanciper est un des facteurs de cette crise.
Université : crise et communication
Authors: Gogoua Ozoua Georgette , Le Monnier de Gouville Sybille
Published: September 2021

À partir d’une simple coupure de courant au sein de l’université, la communication défaillante provoque une série de supputations qui désorganisent progressivement le service d’enseignement universitaire…
La ville, corpus infini pour des pratiques critiques de l'espace
Authors: Loriers Marie-Christine , Vulbeau Alain
Published: September 2021

Sous le terme de « crise » des cités, des quartiers, des banlieues, des villes, se cache un échec des outils pratiques et théoriques de définition et de projet de l’urbanisme. L’hypothèse que nous décidons d’éclairer et d’étayer est que ces outils n’atteignent ni ne travaillent leur objet et leur sujet réels et qu’il faut produire un outillage interpétatif spécifique que nous nommons « Pratiques critiques de l’espace » (PCE) .Nous décrivons différentes situations où les PCE, critiquant le zonage moderne et les cumuls post- modernes, se fondent sur la spontanéité, l’humour, les sociabilités, dans une perspective d’esthétisation des espaces publics.
Development of an operational excellence framework for organisational performance improvement in the Sudanese aviation industry
Authors: Osman Mohamed Ibrahim , Mohammad Roslina , Yusof Sha'ri , Chelliapan Shreeshivadasan
Published: September 2021

Purpose: The purpose of this study is to investigate the Critical Success Factors (CSFs) for successful implementation of Operational Excellence (OE) by the organisations in the Sudanese aviation industry, as well as to determine the resulted impacts in the improved organisational performance and competitive advantage, and to quantify the benefits.Design/methodology/approach: The Critical Success Factors (CSFs) of OE were provided and dissected to reveal its integrated components and their importance levels. These factors include leadership, people management, continuous improvement, operational strategy, and asset optimisation. Also, the impacts (outcomes) further categorised in the four financial results, quality of products or services, efficiency, and satisfaction groups were presented, while the weight of each outcome was highlighted.Findings: With the OE's conceptual framework, the critical success factors to achieve OE were identified. Hence, from the five main factors, the expert panel members suggested the leadership factor to be the most important to achieve OE in the Sudanese aviation industry. Ranking of the five critical success factors and the forty sub factors provided a better understanding of the Sudan situation, specifically concerning the effective implementation of OE philosophy.Research limitations/implications: The findings of the sub-factors reported in this study were not enough. As a result, the future studies must focus on the detailed descriptions of sub-factors that are related to each of the critical factor identified.  Practical implications: Efficiency in the organisations is generated and enhanced when the organisations become efficient in reducing the waste of time, raw materials, unnecessary processing, in addition to the energy used in transportation, storing, and operating plant. Besides, the state of effectiveness is achieved when the organisation achieves its long-term goals through increased customer satisfaction and is able to prove its reason for being. OE is critical as it assures both the efficiency and effectiveness of organisationsOriginality/value: The past research activities have relatively over-emphasised in the unilateral "result-driven" perspective of OE that corresponds with the limited concern for enablers, the critical forms and focus of OE. Thus, this issue is a shortcoming that this paper attempts to address.
Carathéodory properties of Gaussian hypergeometric function associated with differential inequalities in the complex plane
Authors: Oros Georgia Irina ,   Department of Mathematics and Computer Science, University of Oradea, 1  Universitii str., 410087 Oradea, Romania
Published: September 2021

The results presented in this paper highlight the property of the Gaussian hypergeometric function to be a Carathéodory function and refer to certain differential inequalities interpreted in form of inclusion relations for subsets of the complex plane using the means of the theory of differential superordination and the method of subordination chains also known as Löwner chains.
Metodología para la reutilización de aguas grises en viviendas ubicadas en áreas de estrés hídrico y estrés hídrico extremo - Caracterización, calidad y opciones de tratamiento para su reuso en Chile
Authors: Díaz Marco Antonio , Decinti Alejandra , Blanco David , Vasquez Karin
Published: September 2021

El aumento de la población y cambio climático en el país ejerce directa presión sobre el recurso hídrico, generando incertidumbre en su disponibilidad. El norte de Chile es una de las zonas más áridas del mundo, característica que últimamente se extiende también a la zona central, por lo que se hace imprescindible desarrollar una alternativa potencial a esta escasez. El agua gris se presenta como una atractiva oportunidad para aumentar la disponibilidad hídrica, esta es agua residual que excluye las aguas negras, se puede tratar y reutilizar en riego y descarga de inodoros. Este estudio plantea una metodología de selección de sistemas de tratamiento para viviendas en zonas de escasez. Partiendo con la clasificación de tecnologías comúnmente utilizadas, su eficiencia en depuración, características y calidad de afluentes y efluentes respectivamente, obteniendo los porcentajes de consumos diarios de agua gris, y una matriz de selección de para viviendas uni y multifamiliares.
Du contrôle de l’innovation à la créativité : vers un cadre intégrateur
Authors: Bollinger Sophie , Burger-Helmchen Thierry
Published: September 2021

Les travaux sur les différents déterminants du contrôle managérial de l’innovation se sont multipliés ces dernières années. Ces recherches se caractérisent par une grande variété d’innovations étudiées et par la diversité des outils de contrôle employés par les organisations. Dans cet article, nous catégorisons les principaux travaux sur le contrôle de l’innovation en fonction de trois dimensions : type de management, forme de contrôle et mesure de performance. Cette analyse nous permet de clarifier certaines tensions, de la dualité contrôle-créativité, qui découlent du contrôle de l’innovation ou qui sont spécifiques au champ de la créativité.Classification JEL : M10, M4, O32, O39.
Entrepreneuriat et créativité : du détournement à la création de valeur
Authors: Gaffard Jean-Luc
Published: September 2021

De la capacité de l’entrepreneur à concevoir une organisation apte à créer des canaux d’information suffisamment robustes dépendent la nature des innovations effectuées, la façon dont sont exploitées les connaissances scientifiques et techniques, l’usage qui est fait de l’esprit créatif. C’est à cette aune qu’il convient de juger du comportement entrepreneurial, des rythmes imposés par la finance, de la façon dont sont allouées les ressources humaines. La réalité de la créativité réside dans le choix opéré entre recherche de rentes et innovations productives, entre une finance impatiente et une finance patiente, entre flexibilité et rigidité sur les marchés de travail. C’est un choix d’ordre organisationnel et institutionnel.Classification JEL : D21, D23, D47, J53, L26.
Factors Influencing Behavioural Intention to Adopt the QR-Code Payment
Authors: Suo Wen-Jing , Goi Chai-Lee , Goi Mei-Teh , Sim Adriel K. S.
Published: September 2021

This study aims to identify the factors which affect the consumers’ behavioural intention to adopt the Quick response code (QR-code) mobile payment. This study extends the Unified Theory of Acceptance and Use of Technology 2 (UTAUT2) with the personal innovativeness construct. This study reveals that performance expectancy, social influence, habit, price value, and personal innovativeness in information technology are significantly related to behavioural intention to adopt QR-code mobile payment. However, effort expectancy, facilitating conditions, and hedonic motivation are found to be statistically insignificant. This study presents one of the few empirical works investigating the role of consumer innovativeness and thus validates the inclusion of personal innovativeness as constructed in mobile payment adoption research. Findings from this study provide valuable insights for mobile payment application developers and mobile payment marketing teams.
Smart Learning Environment (SLE) in the Fourth Industrial Revolution (IR 4.0)
Authors: Mulyadi Dedi , Huda Miftachul , Gusmian Islah
Published: September 2021

This paper is attempted to examine the explanatory approach in dealing with SLE by advancing online learning sources. The systematic approach of searching for the relevant articles on SLE in IR 4.0 has been widely identified through two electronic databases, Scopus and Web of Sciences. Through adopting such digitally systematic search program, identification was made on the various elements in terms of online learning resources (OLR). This attempts to propose the SLE framework model with an innovative approach in enhancing the learning through incorporating IR 4.0 platform to utilize the variety of information sources together with knowledge attribution in the higher education (HE). The contribution provides theoretical framework with the guideline of well-adapted performance in the educational activities as the new normal trend. In achieving this attainment, the readiness of both instruction facilities and accessibility procedure is significantly the main basis in ensuring the process flow in enlarging the digital learning.
Leaked Mitochondrial C1QBP Inhibits Activation of the DNA Sensor cGAS
Authors: Song Kun , Wu Yakun , Fu Bishi , Wang Lingyan , Hao Wenzhuo , Hua Fang , Sun Yiwen , Dorf Martin E , Li Shitao
Published: September 2021

Cytosolic DNA from pathogens activates the DNA sensor cyclic GMP–AMP (cGAMP) synthase (cGAS) that produces the second messenger, cGAMP. cGAMP triggers a signal cascade leading to type I IFN expression. Host DNA is normally restricted in the cellular compartments of the nucleus and mitochondria. Recent studies have shown that DNA virus infection triggers mitochondrial stress, leading to the release of mitochondrial DNA to the cytosol and activation of cGAS; however, the regulatory mechanism of mitochondrial DNA-mediated cGAS activation is not well elucidated. In this study, we analyzed cGAS protein interactome in mouse RAW264.7 macrophages and found that cGAS interacted with C1QBP. C1QBP predominantly localized in the mitochondria and leaked into the cytosol during DNA virus infection. The leaked C1QBP bound the NTase domain of cGAS and inhibited cGAS enzymatic activity in cells and in vitro. Overexpression of the cytosolic form of C1QBP inhibited cytosolic DNA-elicited innate immune responses and promoted HSV-1 infection. By contrast, deficiency of C1QBP led to the elevated innate immune responses and impaired HSV-1 infection. Taken together, our study suggests that C1QBP is a novel cGAS inhibitor hidden in the mitochondria.
Development and Flight Validation of Proposed Unmanned Aerial System Handling Qualities Requirements
Authors: Ivler Christina M. , Truong Kevin , Kerwin Declan , Otomize Joel , Parmer Danielle , Tischler Mark B. , Gowans Norma
Published: September 2021

Unmanned aerial systems, commonly known as drones, present new opportunities to perform autonomous tasks. Handling qualities requirements for manned vertical lift aircraft have been well defined and documented. The need to define handling qualities requirements for vertical take-off
and landing (VTOL) unmanned aerial systems (UAS) to meet mission demands is of paramount importance for all potential operators and procurement agencies. One way to relate handling qualities specifications of large-scale manned and subscale unmanned aircraft is through Froude dynamic scaling.
Froude dynamic scaling based on hub-to-hub distance has shown great promise in relating the natural frequencies of scaled multicopters. There have been recent efforts to develop a VTOL-UAS handling qualities standard by scaling mission task elements and rating their performance through a Trajectory,
Tracking, and Aggression (TTA) score. This paper proposes a new performance standard adapted from the TTA scoring method, along with a modified Cooper–Harper scale as a VTOL-UAS handling qualities framework that is consistent with the spirit of Aeronautical Design Standard 33 (ADS-33).
These newly proposed performance standards were then validated through simulation and flight testing on a small hexacopter UAS, flown at the University of Portland. A key outcome of this work is the flight verification of a key dynamic response metric, the disturbance rejection bandwidth,
and associated validation of Froude scaling for predicted handling qualities metrics.
Acute heart failure due to COVID-19 related myocardial injury and de novo hypertensive cardiomyopathy: a challenging diagnosis
Authors: Pernigo Matteo , Triggiani Marco , Gavazzi Emanuele , Papa Ilaria , Vaccari Alberto , Fisogni Simona , Costantino Ester , Pasini Gian Franco
Published: September 2021

We report a COVID-19 case with acute heart and kidney failure in a healthy young male. Echocardiography showed severe systolic and diastolic left ventricle dysfunction, with diffuse myocardial thickening. Cardiac MRI showed aspects of focal myocarditis, and hypertensive cardiomyopathy. Renal biopsy demonstrated limited acute tubular injury, and hypertensive kidney disease. Coronary angiography excluded critical stenoses. Unlike what we initially suspected, myocardial inflammation had a limited extent in our patient; severe hypertension causing cardiomyopathy and multi-organ damage, not diagnosed before, was primarily responsible for severe illness. Correct diagnosis and guidelines-directed treatment allowed a favorable course.
Spontaneous pneumothorax associated with COVID-19 pneumonia: a single-centre retrospective study
Authors: Hadzhiminev Velizar , Paunov Lybomir , Dimcheva Teodora , Uchikov Angel , Novakov Ivan
Published: September 2021

Spontaneous pneumothorax (SP) is a rare complication of COVID-19 pneumonia; it affects both intubated and non-intubated patients. The pathogenesis includes barotrauma and pneumatocele formation. In the following article, we present case series of 18 patients with COVID-19 associated pneumothorax - a detailed demographic and clinical analysis were performed. The study revealed that men were more affected than women, especially above the age of 55 years; whilst, the distribution of intubated patients and those with spontaneous breathing were equal. Importantly, tube thoracostomy was the preferred method of treatment. The lethal outcome was observed in all patients on mechanical ventilation, due to the severe course of the underlying disease. The occurrence of pneumothorax in patients with COVID-19 is associated with poorer outcome of the disease, especially in those placed on mechanical ventilation.
Importance of Determining and Establishing Latex Allergy in Orthodontic Patients
Authors: Umar Dilshad , Alrashidi Hanan Ali , Alnazer Heba Abdulaziz , Arnous Waod Ahmed
Published: September 2021

Introduction:

The current study was commended with the aim of assessing the incidence of latex allergy in orthodontic patients.

Materials and Methods:

Silver-coloured orthodontic elastomeric ligatures (modular) from six different manufacturers were selected for the cytotoxicity study, being one of natural latex, two of latex-free and three containing polyurethane. The samples were divided into 6 groups of 15 elastics each. The cytotoxicity of these orthodontic elastics was determined through the dye-uptake technique, which is based on the neutral red absorption by living cells. Different periods of time were considered: 1, 2, 3, 7 and 28 days.

Results:

Among all the respondents to the survey, 7.5% showed positive change after wearing elastics. Most of the positive changes were seen in females

Conclusion:

Safe orthodontics practice is dependent upon recognising patients with allergy along with awareness of etiologic materials.
Awareness and Commitment Towards Precautionary Measures Against COVID-19 Among Residents of Majmaah City, Saudi Arabia
Authors: Ahmad Mohammad Shakil , Shaik Riyaz Ahamed , Ahmad Ritu Kumar , Almutairi Abdulaziz Bader , Alghuyaythat Waleed Khalid , Almutairi Shaden Bader
Published: September 2021

Introduction:

The continued explosive spread of severe acute respiratory syndrome coronavirus-2 worldwide is a crucial problem for all countries. Even though it is becoming increasingly difficult to stop the spread of the virus according to the World Health Organisation, countries need to enforce strict measures to minimise its effects. This study attempts to assess the awareness and compliance of the local population for following the precautionary measures against.

Materials and Methods:

A cross-sectional study was carried out at different districts of Majmaah city, Saudi Arabia. A cross-sectional survey study was carried out at different districts of Majmaah city, Saudi Arabia, and 502 individual's respondents were included in the study. Data were collected using a self-↱administered questionnaire for noting compliance towards protective measures. All participants were informed about the nature of the study and given an informed consent form. Data were collected and analysed using SPSS@ 25 (SPSS Version 25.0. Armonk, Newyork: IBM Corp). Categorical variables were expressed as frequencies and percentages. t-test was applied to compare mean scores.

Results:

There were 502 people who participated in this study, among them 260 (51.8%) were males and 242 (48.2%) females. This study highlighted that the population awareness was good and residents showed strong commitment towards coronavirus disease-2019 (COVID-19) precautionary measures. The overall mean scores for awareness and commitment levels were 6.68 ± 1.04 and 4.00 ± 1.13.

Conclusions:

Most participants in the study had a positive perception of COVID-19 prevention and control. Residents of Saudi Arabia responded well to the threat imposed by COVID-19 and are following their government and health regulatory body's instructions. It is therefore suggested that this would also be a valuable resource for policymakers of Saudi Arabia
Dentists' Concerns About the Control of Coronavirus Disease (COVID-19) in Daily Dental Practice
Authors: Upadhyay Nikee , Shah Monali , Raval Yesha
Published: September 2021

Introduction:

A newly identified viral infection, a global pandemic of coronavirus disease 2019, that began in Wuhan, China, and spread around the world, causing an epidemic of pneumonia (COVlD-19), has infected millions of population, causing social anxiety and panic amongst healthcare professionals and the general public. This study aimed to measure the dentists' anxiety and apprehension of being infected while operating during the latest coronavirus disease (COVlD-19) epidemic through a web-based questionnaire.

Materials and Methods:

An online survey was used to perform a cross-sectional analysis. The well-constructed questionnaire, which consisted of closed-ended questions, was prepared and submitted to dentists of India. A total of 396 people from all over India took part in the survey.

Results:

The debilitating consequences of COVlD-19 caused anxiety and fear in a total of 55.8% of general dental practitioners in India. There were 373 dentists (94.2%) who were mindful of recent developments in care procedures. The majority of dentists, 316 (79.8%), are fearful of contracting COVID-19 from a patient or co-worker, and 309 (78%) dentists are nervous when treating a patient with COVID-19.

Conclusion:

Indian dentists revealed good information regarding COVID-19. However, dentists were comprehensive about the extra precautionary measures that protect them about the virus. A considerable percentage of dentists reflected their anxiety and worries about dental profession due to which they have either changed their services to comply with the rules or shut down their practices for an indefinite time.
Incidence Rate and Epidemiology of Cervical Spinal Injuries and Management in Tertiary Care Hospital of Delhi
Authors: Gupta Khushal , Bharadwaj Rahul , Khatri Bhupender , Krishna Loveneesh G.
Published: September 2021

Introduction:

Cervical spine injuries were the most common problem nowadays that many people experiencing due to high-intensity trauma. In contrast, substantial heterogeneity and lack of data exist among clinical spine trauma epidemiological studies limiting the ability to compare and pool data. The most common mechanism of injury is usually motor vehicle accidents. However, its patient-centered characterisation and quantification are lacking.

Materials and Methods:

Incidence and characteristics of cervical spine injury were identified in the tertiary care hospital of Delhi. Fifty-six cervical spine injuries admitted patients among all 228 spinal trauma patients who presented in the orthopaedic trauma emergency registry were recruited in this study.

Results:

There were 56 subjects identified (8.53%) with cervical spine injury admitted per further evaluation. Among these, 85.7% were male. Mainly age group involve is 20–40 year (median age – 24 year), mostly injured by road traffic accident (RTA) (35.7%). The cervical injury commonly has upper, and subaxial vertebrae fractures and anterolisthesis are much common than retrolisthesis. The hospital stay of listhesis patient is usually more than disc bulge patients. Halovent application is more common in the upper cervical (c1–c2), like anterior cervical plating with dissectomy is common in disc bulge cervical patients.

Conclusion:

Cervical spinal injury is associated with RTA in the young age group. A head injury like trauma should take into consideration in every cervical patient. Early management with better operative techniques can decrease hospital stay and increase the recovery rate of patients.
Piezosurgery – a sanctifying invention for osseous surgeries in periodontics and implant dentistry
Authors: Poornima Rajendran
Published: September 2021

The use of various hard tissue cutting instruments like micromotors and carbide burs pose a certain disadvantage such as excessive heat generation, smear layer formation, difficulty in controlling the bleeding of the operating field, etc. These disadvantages not only increase the intraoperative time but also affects the overall prognosis of the treatment. At present, the use of power ultrasonics has gained popularity over conventional techniques for procedures involving hard tissues. It overcomes the various disadvantages of traditional instruments as well as provides increased precision, protection of both soft and hard tissues as well as hastens the healing after osseous surgeries. The present review article aims to highlight the impact created by the piezoelectric devices in various dental procedures, specifically periodontal and implant related therapies, its mechanism of action and the advantages over conventional osseous surgeries.
Forsythosides as Essential Components of Forsythia-based Traditional Chinese Medicines Used to Treat Inflammatory Diseases and COVID-19
Authors: Bailly Christian
Published: September 2021

The dried fruits of the plant Forsythia suspensa (Forsythia Fructus: Lianqiao in Chinese) are used in many herbal preparations to treat various diseases or the associated symptoms. Forsythia extracts contain phenylethanoid glycosides (PhGs) such as the forsythosides (Fst A-to-P). The leading products, Fst-A,-B and-F (arenarioside), can be found also in >90 other plants inventoried here. The pharmacological properties of Fst are reviewed, with emphasis on their anticancer, antiviral, and antibacterial activities, which essentially derive from their anti-inflammatory and antioxidant effects. Fst-B functions as a potential binder of the repressor protein Kelch-like ECH-association protein 1 (Keap 1), thus promoting the nuclear translocation of the transcription factor Nuclear factor erythroid 2-related factor 2 (Nrf2) implicated in the subsequent activation of the production of antioxidant enzymes and repression of the oxidative stress. The regulation of the Nrf2/Heme oxygenase-1 pathway is the central piece of the multifaceted mechanism of action of Fst-A/B. Their prominent antioxidant and anti-inflammatory effects support the use of these compounds in different inflammation-related diseases and conditions, from sepsis to neuroprotection and many other pathologies discussed here. In addition, these properties contribute to the antiviral action of the compounds. Fst-A/B displays activities against the influenza A virus and different Fst-containing traditional Chinese medicinal (TCMs) have revealed beneficial effects to combat the current COVID-19 pandemic. The mechanisms whereby Fst-A/B could inhibit viral multiplication are discussed. PhGs likely contribute to the anti-COVID-19 activities reported with several TCM such as Shuang-Huang-Lian oral liquid, Lianhua-Qingwen capsules, and others. This review highlights the pharmacological profile of Fst and illustrates health benefits associated with the use of Forsythia Fructus.
Predicting the 7th Day Efficacy of Acupoint Application of Chinese Herbs (Xiao Zhong Zhi Tong Tie) in Patients with Diarrhea – A Machine-Learning Model Based on XGBoost Algorithm
Authors: Sheng Song , Li Rui , Wang Xing , Gao Hong-Yang , Zhang Yan-Hong , Xu Feng-Qin
Published: September 2021

Objective:

Extreme gradient boosting (XGBoost) was used to predict the 7th day efficacy of the acupoint application (AP) of Chinese herbs (Xiao Zhong Zhi Tong Tie) in patients with diarrhea.

Materials and Methods:

We consecutively collected medical records of patients with diarrhea nationwide on the Chun Bo Wan Xiang cloud platform from August 22 to November 5, 2020. Demographic and clinical data and the fecal properties were included in this study. We established the XGBoost model to predict the 7th day efficacy of AP in patients with diarrhea. The XGBoost model was evaluated using the area under the receiver operating characteristic (ROC) curve (AUC). We next compared the performance of XGBoost with that of artificial neural network (ANN), ANN + boosting, ANN + bagging, and support vector machine (SVM).

Results:

The XGBoost model provided a prediction accuracy of 84.86% (95% confidence interval = 82.74% to 86.81%) and the ROC curve analysis showed an AUC of 0.81. The top-three variables with the highest importance are age, duration of diarrhea, and region (North). Our study revealed that XGBoost was not superior to ANN, ANN + boosting, ANN + bagging, and SVM.

Conclusions:

The established XGBoost model for predicting the 7th day efficacy of AP in patients with diarrhea exhibited good accuracy and precision, which can be used for efficacy prediction.