bluuebunny/crossref_metadata_2025 huggingface dataset:
Innovative Role-Play Strategies in Business Ethics Education: The ChatGPT Approach
Authors: Xu Xiao
Published: February 2024

ChatGPT, a chatbot representing generative artificial intelligence (AI), has rapidly gained transformative power in various areas since its launch in late 2022. This paper explores the innovative integration of ChatGPT in teaching business ethics, contrasting it with traditional role-play methodologies. Utilizing existing role-play learning activity designs, we provide a comparative analysis of these approaches based on the four key pillars identified by Boud & Prosser (2002), which include learner engagement, acknowledgment of the learning context, learner challenge, and practical involvement. Additionally, we analyze the 'simulation triad' of time, group dynamics, and environment to evaluate the efficiency of the GPT-powered learning design, as presented by Wills et al. (2011). Our analysis reveals that ChatGPT in business ethics education offers a novel approach to learning, effectively breaking through traditional boundaries while cultivating an enriched, accessible learning experience. We suggest that a hybrid model, which combines the strengths of both traditional and GPT-enhanced methods, is the optimal approach for comprehensive ethics education in the business field.
Common Complications in Infants Born to Diabetic Mothers
Authors: Shah Syed Bawar , Bawar Shandana , Wajeeha . , Farooq Nazish
Published: February 2024

Infants of diabetic mothers are at increased risk of complications. There is always a need for more research on this topic to look for complications and make strategies for prevention and management. Objectives: To determine the frequency of complications in infants born to diabetic mothers. Methods: This descriptive study was done at the Department of Pediatrics, Molvi Ameer Shah Memorial Hospital, Peshawar from 1st January 2022 to 31st December 2022. A total of 150 infants born to diabetic mothers were enrolled after written informed consent and frequencies of complications were noted. Data were analyzed using SPSS 24.0. Results: The mean age of the patients was 3.08 ± 1.7 days. The minimum age was 1 day, and the maximum was 7 days. The mean age of the mother was 26.9 ± 4.07 years. The mean gestational age was 36.9 ± 1.4 weeks. The mean duration of diabetes was 7.6 ± 1.14 years. The mean HbA1c level was 7.27 ± 2.41. There were 38% males and 62% female. Adequate diabetic control was present in 24.7% of patients while 75.3% had poor diabetic control. The most common complication was hypoglycemia in 24.7% followed by Macrosomia in 22.7%, prematurity in 20%, hyperbilirubinemia 11.3%, hypocalcemia in 10.7% and polycythemia in 10.7% patients. Conclusions: Most common complication was hypoglycemia followed by macrosomia, prematurity, hyperbilirubinemia, hypocalcemia, and polycythemia. However, due to its limited sample size, the results may not be generalizable.
Do metaphors help or hinder second language vocabulary acquisition?
Authors: Howe Rachael
Published: February 2024

The use of non-literal language and its influence on second language (L2) vocabulary acquisition is a widely debated topic. This article focuses specifically on the role of metaphors as an example of non-literal language and a pragmatics related phenomenon, beginning with how conceptual and enactment-based metaphor awareness can support L2 vocabulary acquisition. Opposing arguments suggesting that metaphor may hinder L2 vocabulary learning are also explored, such as the role of an individual’s first language (L1), along with insufficient vocabulary size and depth. Implications for both L2 vocabulary research and practice are discussed before reaching an overall conclusion.
Growth of horned melon (Cucumis metuliferus) under different levels of Trichoderma-based bio-fertilizer
Authors: Mutetwa Moses , Mtaita Tuarira , Ngezimana Wonder , Chaibva Paul
Published: February 2024

Implementing practices such as organic agriculture, sustainable agriculture, or ecological agriculture can greatly reduce and eliminate the harmful effects of synthetic fertilizers on both human health and the environment. In efforts to promote a more environmentally friendly approach, this study was conducted at the Department of Horticulture and Agronomy, Midlands State University in Zimbabwe. The focus was on the use of Trichoderma bio-fertilizer at various levels to determine its impact on the growth of horned melon (Cucumis metuliferus) in a greenhouse setting. The experiment followed a Complete Randomized Design (CRD) and included four different Trichoderma-based biofertilizer treatments, as well as a control treatment [0 g/pot (control), 0.1 g/pot, 0.2 g/pot, 0.3 g/pot, and 0.4 g/pot], all replicated four times. The research findings indicate that the biofertilizer utilized had a significant impact (p ≤ 0.05) on vine length, number of leaves, and branches for growth characteristics. However, the biofertilizer did not have a significant effect (p ≥ 0.05) on stem girth, chlorophyll content, or branching pattern. This study reveals that the horned melon plants treated with the Trichoderma-based biofertilizer exhibited noticeable changes in their vegetative growth, flowering patterns, and fruiting features at different application levels. Further investigation is required to fully understand the potential benefits of using Trichoderma-based biofertilizer in horned melon cultivation.
The Use of Levels One and Two Dermatoglyphics for Sex Identification in University of Ibadan Community, Southwest Nigeria
Authors: Adetona M.O. , Preyor E.
Published: February 2024

Dermatoglyphic traits are genetically determined and remain constant until death. Dermatoglyphics features are arranged from patterns, minutiae and ridgeology. This study utilized patterns and minutiae details of fingerprints as a means of sexual differentiation amongst the University of Ibadan community. Three hundred and eighty-four (192 males and 192 females) participants from the University of Ibadan community were recruited using multistage sampling technique. Fingerprints were obtained using fingerprint scanner Dermalog LF10, Hamburg, Germany. GraphPad Prism 7.0 was used for the test of mean of variables. Ulnar loop, whorl and radial loop patterns were found to be predominantly distributed in both male and female in that order. However, the arch pattern was significantly different between female and male. The male subjects had significantly higher total finger ridge count (TFRC). All the analysed minutiae were significantly different between male and female except bridge. The arch pattern, TFRC and level 2 details (minutiae) of dermatoglyphics could be used as markers for sexual differentiation.
Protocatechuic acid modulates hepatic oxidative stress and inflammation linked to DMN exposure in rat
Authors: Asejeje Folake , Etim Sylvia , Asejeje Gbolahan , Iwuoh Benneth Chukwudi , Akintade Sanmi Ibukunoluwa , Adedara Isaac , Farombi Ebenezer Olatunde
Published: February 2024

Dimethyl nitrosamine (DMN), a potent hepatotoxin, exerts carcinogenic effects and induces hepatic necrosis in experimental animals via CYP2E1 metabolic activation, and generation of reactive oxygen species (ROS). Protocatechuic acid (PCA), a plant-based simple phenolic compound and potent antioxidant, has been shown to affect the development of neoplasia in the rat liver and inhibit the initiation or progression phases of most cancers. In this study, the modulatory effects of PCA on DMN-induced hepatotoxicity, oxidative stress, inflammation, and selected phase I xenobiotic metabolizing enzymes were investigated in male Wistar rats. This study assessed biomarkers of hepatic injury (alanine transaminase, aspartate aminotransferase, alkaline phosphatase, and gamma- glutamyl transferase); oxidative stress (hydrogen peroxide concentration, lipid peroxidation, and reduced glutathione levels); measured activities of antioxidant enzymes (catalase, sodium dismutase, glutathione peroxidase, glutathione S-transferase); and inflammation (Tumor necrosis factor (TNF)-α, interleukin-1-Beta (IL-1β) and iNOS). The results of our investigation demonstrated that pretreatment with PCA at 50 and 100 mg/kg body weight p.o. reduced DMN (20 mg/kg bw) i.p. mediated hepatic injury, oxidative stress, and inflammation in a dose-dependent manner. In addition, the activities of phase I metabolizing enzymes were significantly induced except for aminopyrine-N-demethylase in the DMN-treated rats when compared with the DMN alone control group. This induction was also reversed by pre-treatment with PCA. The result of this study suggests that PCA is hepatoprotective against DMN-induced hepatic damage by its ability to suppress oxidative stress, inflammation, and modulate the activities of the selected phase I drug metabolizing enzymes. Thus, PCA may prove useful in combating DMN-induced hepatic damage
Molecular Genetic Basis of Cervical Cancer
Authors: Asotic Anida , Doric Mirsad
Published: February 2024

Background: Cervical cancer is a cancer that occurs in the cells of the cervix–the lower part of the uterus that connects it to the vagina and represents a global public health problem. In 2008, 530,000 new cases and 275,000 deaths from cervical cancer were recorded worldwide, and in 2018, an increase to 570,000 new cases and 311,000 deaths was recorded. For many years, it has been known that the main cause of preinvasive lesions and cervical cancer is the human papillomavirus–HPV. The total prevalence of HPV in the cervix in the general population of women is 10%. In developing countries, this prevalence is higher and describe most frequent clinical manifestations in the praxis. Objective: The aim of this study was to analyze and describe molecular genetic basis of cervical cancer and the most frequent clinical manifestations in the praxis. Methods: This is cross-sectional study based on meta-analysis of the facts published in scientific literature stored in indexed databases Medline, PubMed Central, Scopus, Hinari, etc., about molecular genetic basis of the cervical cancer with description of clinical manifestations and its consequences describing morbidity and mortality rate in the population worldwide. Results and Discussion:  In 2008, 530,000 new cases and 275,000 deaths from cervical cancer were recorded worldwide, and in 2018, an increase to 570,000 new cases and 311,000 deaths was recorded. The main cause of preinvasive lesions and cervical cancer is the human papillomavirus–HPV. HPV infection is most common in young, sexually active women under the age of 25, but cervical cancer is more common in older women. Oncogenic types of human papillomavirus 16 and 18 together with HPV 45 and 31 are the causative agents of 80% of cervical cancer cases. HPV 16 has the highest oncogenic potential. Epigenetic changes include DNA methylation and post-translational modifications of histones, such as: methylation, acetylation, phosphorylation, ubiquitination and sumoylation. Cervical intraepithelial (CIN / SIL) lesion is a premalignant change of the cervix that occurs due to chronic infection with high-risk types of HPV. Persistent infection with oncogenic types of HPV causes almost all cases of cancer. HPV DNA was detected in 99.7% of cancer samples. Conclusion: There are four main steps in the development of cervical cancer: infection of the metaplastic epithelium of the transformation zone, viral persistence, progression towards precancerous lesions and invasion of the basement membrane. Histologically, in about 80% of cases, squamous cell carcinomas arise from preexisting dysplasias. Adenocarcinoma accounts for about 15-20% of cancer cases. HPV 16 is the main cause of squamous cell carcinoma, unlike HPV 18 which is typically associated with adenocarcinoma.
ANALISIS PENGARUH DEBAT CALON PRESIDEN 2024 PERTAMA TERHADAP ELEKTABILITAS CALON PRESIDEN PERSPEKTIF PANDANGAN MASYARAKAT
Authors: Citra Widayanti  , Yulita Nilam Fridiyanti
Published: February 2024

Pemilihan Presiden Indonesia 2024 menjadi fokus perhatian dengan perdebatan calon presiden yang dianggap momen krusial dalam menentukan elektabilitas kandidat. Survei elektabilitas oleh lembaga seperti Centre for Strategic and International Studies (CSIS) dan Indonesia Polling Stations (IPS) menunjukkan Prabowo Subianto-Gibran Rakabuming Raka mendominasi setelah debat. Meskipun ada skeptisisme terkait ketepatan survei, Tim Pemenangan Nasional (TPN) Ganjar-Mahfud mengandalkan survei internal dan sentimen media sosial sebagai fokus utama. Analisis sentimen masyarakat melalui media sosial menggunakan algoritma Support Vector Machine (SVM) menyoroti pengaruh positif Gibran Rakabuming Raka dalam meningkatkan elektabilitas Prabowo-Gibran. Lembaga survei terkemuka, seperti Roy Morgan, Litbang Kompas, LSI Denny JA, Indikator Politik, dan Poltracking Indonesia, memberikan wawasan elektabilitas yang berbeda, mencerminkan dinamika politik menjelang pemilihan. Penelitian ini melibatkan literature review dari berbagai sumber, menggali konsep elektabilitas dan dampak debat politik. Teori komunikasi politik dan psikologi politik menjadi landasan untuk memahami bagaimana pesan dari debat mempengaruhi preferensi pemilih. Dampak debat pertama tidak hanya sementara, melainkan membentuk narasi jangka panjang. Pidato yang kuat dan respons terhadap isu-isu penting menciptakan kesan mendalam pada pemilih. Evaluasi diri dan perbaikan pasca debat, serta dinamika koalisi politik dan strategi politik pasca debat, menjadi elemen penting dalam menjaga elektabilitas. Pemahaman mendalam terhadap elektabilitas pasca debat menjadi kunci dalam menyikapi dinamika politik menjelang Pemilihan Presiden 2024.
A Survey On Physical Activity Monitoring (PAM) Among Malaysian Young Adults
Authors: Krishnan Vasanthi Rajkumar , Murugayah Kishanthini , Jayaprabha Surendran Praveen , Nadzalan Ali Md , Purushothaman Vinosh Kumar , Muniandy Yughdtheswari , Sadasivam Sivabavani
Published: February 2024

Background: Physical Activity Monitoring (PAM) is used effectively to encourage and promote an increased level of Physical Activity (PA) in young adults. The aim of this study was to determine the status of PAM and to identify the type of monitoring method being used among young adults in Malaysia is avoid health risks.
Methods: In this cross-sectional study, the data collection was based on a validated customized questionnaire carried out by sending it online via email, WhatsApp, and Facebook with an explanation of the research background, including the link of the survey questionnaires to the respondents.
Results: A total of 400 participants completed this survey and most participants were in the age range between 25-29 and 50.7% were males. Nearly half of the participants (61.0%) declared that they were monitoring their PA regularly and smartwatches (20.5%) are the most preferable type for PAM.
Conclusion: In this survey, it can be concluded that more awareness needs to be created on the importance of PAM among young adults as nearly another half of the participants surveyed that they were not monitoring their regular PA to follow a healthy lifestyle.
2023/27 The obligation to record working time in the light of European and national (German) case law – Part 2 (GE)
Authors: Schreiner Paul , Stephan Nina
Published: February 2024

2023/27 The obligation to record working time in the light of European and national (German) case law – Part 2 (GE)

This article deals with the aftermath of the ECJ’s CCOO judgment (14 May 2019, C-55/18), which has been a major issue in various EU jurisdictions. The article consists of two parts. This second part discusses some particular consequences in Germany.
Innovation As The Competitiveness Of Maritime Universities In Semarang
Authors: Agus Aji Samekto  , Lilik Kustiani  , Syaiful Arifin
Published: February 2024

Increasingly fierce competition causes university managers, both private universities (PTS) and public universities (PTN), to maximize existing resources. Not only on resource management but also must pay attention to the ability of each unit or part of the college that has selling value to the community, has something different from competitors and also pays attention, implements regulations from the government and has differentiation. Innovation gets the attention of maritime universities in Semarang by making continuous improvements. In addition to continuous improvement, they also make overall changes. The competitive advantage of maritime universities in Semarang is able to provide the best quality by getting a quality standard assessment from IMO, ISO, and having an international standard network. Maritime Universities in Semarang are universities that have differences compared to universities in general. It is something different and has a uniqueness, but like other universities, massively also has a strategy to increase competitive advantage, so the hope of maritime college in Semarang is to have many and sustainable students.
Cidade e participação: uma proposta alternativa à luz da “democracia como cooperação reflexiva” de Axel Honneth
Authors: Levy Wilson , De Brelàz Gabriela
Published: February 2024

os debates contemporâneos sobre participação social nas cidades ultrapassaram há muito as fronteiras da filosofia política e da teoria democrática, alcançando reflexões no campo do planejamento urbano e em áreas correlatas. Nesses debates, têm ganhado força leituras alternativas sobre a democracia participativa, extrapolando em muito seus elementos formais e arranjos institucionais. Um desafio que se coloca aqui é se a mera existência de espaços formais é capaz de gerar engajamento e adesão dos cidadãos a esses espaços. O presente artigo pretende discutir este problema, mobilizando, para tanto, a ideia de democracia como cooperação reflexiva, de Axel Honneth, como conceito apto a enfrentá-lo. Objetiva-se, com isso, compreender como é possível obter mais engajamento da sociedade nos debates relativos à política urbana. Espera-se como resultado contribuir com uma parte importante desta discussão, que é essencial ao aperfeiçoamento da percepção da democracia nas cidades.
Validação de instrumento para acompanhamento do processo formativo de aprendizagem em um currículo integrado
Authors: De Mendonça Leonardo Teixeira , De Mendonça Kamylly Reina Carneiro , Sefer Celina Claudia Israel , Santos-Lobato Edienny Viana , Portella Marcia Bitar
Published: February 2024

A avaliação formativa é característica central de qualquer currículo integrado, sendo ponte entre o ensino e o aprendizado. Esse estudo desenvolveu e validou o conteúdo de dois instrumentos para o acompanhamento do processo formativo de aprendizagem com enfoque em habilidades, atitudes e comportamento dos discentes de um curso de medicina baseado que utiliza estratégias metodológicas ativas de aprendizagem em currículo. A validação foi baseada no método Delphi com duas rodadas. Foram validados dois instrumentos, sendo um para sessões tutoriais e outro para o eixo de habilidades clínicas. O conteúdo foi considerado relevante e com concordância elevada, e será capaz de servir com guia para uma melhor avaliação formativa de habilidades, atitudes e comportamento.
Optimization of the fermentation process for mead production: a review
Authors: Queiroz Edinara Lacerda , De Almeida Tamires Bastos , E Silva Anne Kettery Carneiro , Anunciação Adriana Soares , De Souza Sílvia Maria Almeida , Martínez Ernesto Acosta
Published: February 2024

Honey is a food product characterized by being viscous, aromatic and with a high concentration of glucose and fructose sugars, produced by bees and has been used for centuries in the preparation of drinks. Mead is the product obtained by fermenting the mead wort and water, with high added value, which can be added from fruits, herbs and spices. Mead is one of the oldest alcoholic beverages consumed by man and is part of the history of many civilizations. Currently in many countries of the world its production and consumption is quite considerable, being a product of high added value. The production of mead still occurs in an artisanal manner, demonstrating the need for research that improves, optimizes and reduces the costs of the productive process. The processing depends on many factors, among them the composition of the honey, the yeast used, the fermentation methods and parameters and the additives, factors directly interfere in its sensory quality. This article will address the aspects related to the production and optimization of the process for obtaining mead, with techniques that have been used in scientific research to ensure reduction of fermentation time and a quality final product, such as use of different raw materials, innovative supplements, process steps and methods.
Formas de tratamento do Lúpus eritematoso sistêmico: uma revisão de literatura
Authors: De Paiva Maykon Jhuly Martins , Cubas Alice Munhoz , Pereira Júnior Cledson Almeida , Almeida Cleisla Maria de Lima , Feitosa Isadora Carvalho , Da Silva Luana Teixeira , Dos Santos Taides Tavares
Published: February 2024

Introdução: O Lúpus eritematoso Sistêmico (LES) se caracteriza como uma doença autoimune, causando processos inflamatórios em órgãos de vários sistemas, os quais se manifestam como lesões erosivas pelo corpo, além de cansaço, edemas, dores, fadiga, entre outros. Ademais, o diagnóstico é sintomático e por exames de apoio, como o teste de FAN.  Metodologia: Nessa égide, esta revisão de literatura integrativa tem como objetivo realizar uma busca de fármacos utilizados no tratamento do LES, bem como identificar os principais tipos utilizados, os princípios ativos e seus efeitos em pacientes com LES. Resultados: Outrossim, os resultados partiram de um apanhado de estudos, que foram selecionados por meio de critérios de exclusão e inclusão nas bases de dados, dos quais restaram 20 artigos. Nesse sentido, em relação aos segmentos para o tratamento do LES, foram encontrados medicamentos como anti-inflamatórios não esteróides e anti-reumáticos, assim como outras terapias biológicas, como fitoterapia e suplementação, com propósitos de prevenção, entre outros. Conclusão: Por fim, conclui-se que as pesquisas a respeito de formas de tratamento para o LES já apresentam vários resultados promissores. Entretanto, se faz necessário novas buscas para meios farmacêuticos de tratamento e manejo clínico para essa doença.
Principais complicações tardias após tratamento do Câncer de Mama em mulheres idosas: uma revisão integrativa
Authors: Gama Alinne Cristine Carvalho , De Lima Jucélia Moraes , Da Silva Liliane Santos , De Almeida Emerson Willian Santos , Coêlho Wender Gonçalves , Braga Pollyanna Guimarães , Lemes Alisséia Guimarães , Costa Gilka Paiva Oliveira
Published: February 2024

Este estudo teve como objetivo identificar as evidências científicas acerca das principais complicações tardias após o tratamento do câncer de mama em mulheres idosas. Trata-se de uma revisão integrativa da literatura, foram incluidos estudos originais que evidenciaram as principais complicações tardias do tratamento de câncer de mama, que incluam mulheres idosas com 60 anos ou mais, publicados nos últimos 10 anos. A busca foi realizada nas bases de dados: Web of Science, PubMed, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Scientific Electronic Library Online (Scielo), e Base de Dados em Enfermagem (BDENF), a partir de descritores padronizados pelo Descritores em Ciências da Saúde (DeCS) e o Medical Subject Headings (MeSH), ("breast neoplasms") AND ("aged") AND ("postoperative complications"), particulares para cada base, com o operador booleano AND. Foram encontrados 163 artigos, sendo incluídos 20 para leitura na íntegra e, 4 compuseram este estudo. Os resultados revelam que os principais sintomas tardios foram os depressivos, fadiga e problemas cognitivos, padrões temporais de qualidade de vida geral, função física, cognitiva, e problemas financeiros, morbidade do braço, linfedema, dor ou dificuldade em subir ou mover-se para os lados, amplitude total de movimento, hipoestesia, dor pós-operatória persistente após cirurgia de câncer de mama, linfedema do braço, redução da força de preensão e abdução do ombro, dor provocada. É necessário estratégias de educação e prevenção para a redução dessas complicações ou que viabilizem melhor convivência com ela, a fim de proporcionar qualidade de vida a essas mulheres.
MEMPERTAHANKAN DAN MENINGKATKAN PENJUALAN PRODUK BATIK PEMALANG DI ERA DIGITAL
Authors: Agustin Sapta Rini  , Achmad Fauzi
Published: February 2024

Artikel ini membahas tentang mempertahankan dan meningkatkan penjualan produk batik Pemalang di Era Digital, Literature Review. Arah pengamatan ini untuk memperoleh asumsi mengenai mempertahankan dan meningkatkan penjualan produk batik Pemalang di Era Digital. Supaya dapat digunakan di penelitian selanjutnya. Temuan dari program – program ini yakni : 1) Persediaan bahan baku berpengaruh meningkatkan penjualan; 2) Kurangnya tenaga pembatik berpengaruh meningkatkan penjualan; 3) Promosi produk berpengaruh meningkatkan penjualan; 4) Sistem pemasaran serta cara bertransaksi berpengaruh meningkatkan penjualan. Kota Pemalang terkenal akan kuliner serta keindahan alamnya. Hal tersebut menjadi inspirasi Batik Arta Kencana dalam membuat corak dan motif batik sebagai ciri khas batik Pemalang.Untuk mempertahankan dan meningkatkan penjualan perlu dilakukan strategi pemasaran yang direncanakan dan dilakukan secara terus menerus, agar penjualan meningkat sehingga dapat mempertahankan usahanya. Di Era Digital, produsen menggunakan Digital Marketing melalui media sosial dan web sebagai alat promosi juga melayani pesanan dan bertransaksi. Penelitian ini menggunakan pendekatan kualitas dengan metode studi kasus. Sedangkan metode pengumpulan data yang di gunakan yaitu wawancara, observasi, dokumentasi. Semua kegiatan pengenalan produk serta transaksi dapat dilihat pada instagram https://www.instagram.com >batik pemalang.
PENGARUH KOMPENSASI DAN DISIPLIN KERJA TERHADAP KINERJA KARYAWAN (STUDI PADA PERUSAHAAN THE FASHION)
Authors: Nur Malita Sari  , Achmad Fauzi
Published: February 2024

Kompensasi yang diberikan oleh perusahaan The Fashion telah diberikan sebagaimana mestinya dan aturan perusahaan yang menetapkan kedipilinan kerja juga diperhatikan dengan baik namun omset setiap bulan di perusahaan The Fashion mengalami perurunan setiap bulannya selama 6 (enam) bulan terakhir. Penelitian ini bertujuan untuk menganalisis pengaruh kompensasi dan disiplin kerja terhadap kinerja karyawan. Populasi pada penelitian ini adalah Sales Promotion Perusahaan The Fashion berjumlah 41 orang. Dengan bantuan kuesioner, penyusunan data dilakukan melalui metode survei. SPSS 26 digunakan untuk menganalisis data. pengujian koefisien determinasi (R2), dan pengujian hipotesis (uji t). Studi ini menemukan bahwa kompensasi dan tingkat disiplin dalam bekerja memiliki efek yang positif dan signifikan terhadap kinerja karyawan.
Influence of Minimal Residual Disease at Day 15 of Induction Therapy on Survival of Children with Acute Lymphoblastic Leukemia
Authors: Samardžić-Predojević Jelica , Đurđević-Banjac Biljana , Malčić-Zanić Dragana
Published: February 2024

Objective. The aim of the study was to evaluate the impact of minimal residual disease (MRD) on day 15 of induction therapy (d15) on the treatment outcome in children with acute lymphoblastic leukemia (ALL).

Materials and Methods. The study included 74 patients (1-18 years) with ALL, who were treated at the Pediatric Clinic of the University Clinical Center Banja Luka from January 2011 to May 2021. All patients were treated according to ALL IC-BFM 2009 protocol. MRD on bone mar- row was assessed d15, using the multiparameter flow cytometry method (FCM).

Results. Of all, 59.46% of patients had MRD d15 0.1−10%, MRD<0.1% had 18.92% of patients, and 21.62% had MRD >10%. Patients with the lowest MRD had the highest 5-year overall survival (OS) and event-free survival (89.5% and 91% respectively) and the lowest cumulative risk for relapse or death (9.7% and 8.1%), in contrast to patients with MRD>10% in whom OS was 80.0%, and the risk of recurrence is 20%. Predicted MRD d15 was significantly associated with prednisone response assessed in the peripheral blood on day 8 (P<0.001) and statistically significantly positive correlation (r=0.498; P<0.001) was found.

Conclusion. MRD measurement d15 has a great prognostic significance for patients in the standard and high risk groups, but not for patients in the intermediate risk group. The introduction of additional testing is necessary for better identification of patients with an increased risk of disease recurrence.
Alternative Resolution of Legal Vacances Guarantee of Aircraft Particularly Aircraft and Helicopters for The Interests Of Creditors In Indonesia
Authors: Yuniarto Efran
Published: February 2024

Since the enactment of Law Number 1 of 2009 concerning Aviation, replacing Law Number 15 of 1992, there has been a legal gap regarding guarantees for airplanes and helicopters in Indonesia, leaving creditors unprotected. While foreign creditors benefit from charges for international interests on aircraft, such as Irrevocable Deregistration and Export Request Authorization (IDERA), domestic creditors are left facing unjust conditions. To address this issue and provide legal certainty for creditors in Indonesia, one alternative is to use the provisions of the material guarantee law, including the use of guaranteed institutions like Fiduciary, and to reconstruct existing laws to allow for the granting of material security rights in the form of mortgages.
ESTUDIO DEL IMPACTO PRODUCTIVO DE UN FERTILIZANTE ORGÁNICO EN UN SEMILLERO
Authors: Vásquez Cortez Luis Humberto , Gavilanez Montesdeoca Sixto Alejandro , Cargua Flores Nataly Silvana , Garcia Larreta Frella Soraya
Published: February 2024

La lombricultura constituye una práctica importante para el reciclaje de algunos desechos generados por la agricultura y agroindustria, en subproductos que puedan utilizarse para la mejora del suelo. Para verificar este estudio de la lombriz roja californiana hemos optado aplicarlo en el vivero “San Antonio” con la intensión de saber qué tan bueno es este humus para así poderlo llevar al mercado y mediante una entrevista a los agricultores de dicho lugar hemos tenido los resultados requeridos. El uso de la lombriz roja californiana (Eisenia Foetida) en los viveros de Lago Agrio para el cultivo de cacao, consiste en una técnica de crianza en cautiverio de lombrices, cuyo objetivo es la producción de humus, el cual es un abono enteramente orgánico, herramienta alternativa para un desarrollo sustentable, con la finalidad de mejorar la calidad de suelo. Han dado gran resultado tanto como producción y calidad en los productos como en ventas de dicho lugar, por ende, podemos decir que la venta del humus de lombriz roja californiana dará un alto nivel económico. El humus de lombriz proporciona un medio económicamente factible, ecológico y aceptable, disminuyendo el uso de fertilizantes químicos, mediante la crianza de lombrices que se encargan del proceso de descomposición del material orgánico generando un 60% Humus para el potencial uso en el vivero “San Antonio” perteneciente al cantón Lago Agrio.
Energy Security in National Security Strategies: A Multiple Case Study
Authors: Lis Andrzej
Published: February 2024

The aim of the study is to identify energy security issues in the assumptions of national security strategic documents. The study seeks responses to the following research questions: (1) What aspects of energy security are included in national security strategies? (2) Are national security strategies oriented to a comprehensive approach combining the issue of energy security with economic competitiveness and environmental sustainability or to a narrow view of energy security as continuity of energy supplies? A multiple case study analysis of national strategic documents of selected NATO Member States — i.e., the United States, the United Kingdom, France, Germany, and Poland, was employed to achieve the research aim.
Regionalne inteligentne specjalizacje i zrównoważony rozwój: wyzwania Europejskiego Zielonego Ładu
Authors: Sabal Maciej
Published: February 2024

Ogłoszenie Europejskiego Zielonego Ładu w 2019 r. było ważnym kamieniem milowym w Unii Europejskiej w zakresie wdrażania podstawowych zasad zrównoważonego rozwoju. Od tego czasu większość dokumentów strategicznych we Wspólnocie, ale także w krajach i regionach, odnosi się do tej koncepcji. Ważną zmianą w stosunku do poprzedniej strategii Europa 2020, ogłoszonej w 2010 r., było oparcie się na polityce ukierunkowanej terytorialnie, co znalazło odzwierciedlenie w ustanowieniu inteligentnych specjalizacji na poziomie krajowym i regionalnym. Chociaż poprzednia strategia również odnosiła się do zrównoważonego rozwoju, specjalizacje nie dotyczyły wyraźnie tej koncepcji. Celem artykułu jest przegląd Regionalnych Inteligentnych Specjalizacji (RS3) w polskich regionach w kontekście koncepcji zrównoważonego rozwoju oraz rekomendacje dotyczące modyfikacji tych specjalizacji, by dostosować je do podstawowych obszarów wskazanych w Europejskim Zielonym Ładzie. W artykule wykorzystano analizę danych zastanych, przegląd literatury oraz odniesiono się do kluczowych dokumentów strategicznych Unii Europejskiej.
ANALYSIS OF CONFLICT RESOLUTION OF BAMBOO HARVESTING LAND BOUNDARIES IN GOLEWA DISTRICT, NGADA REGENCY, EAST NUSA TENGGARA PROVINCE
Authors: Yohanes C. Kolo Meko  , Maria M. E Purnama  , Pamona Sinaga
Published: February 2024

Dalam pemanfaatan bambu di pedesaan terdapat beberapa kendala yang dihadapi baik itu dalam proses pembibitan, pemeliharaan,pemanenan hingga pemasaran, kendala yang terjadi pada pemanenan adalah masalah penebangan yak tak ideal serta masalah konflik tapal batas lahan pemanenan bambu. Berdasarkan observasi yang telah dilakukan di 16 desa yang berada di wilayah administratif Kecamatan Golewa ditemukan lima kasus yang terletak di empat desa yang berbeda yaitu : Desa Ratogesa, Desa Dadawea, Desa Radabags dan Desa Were Iv, masalah yang serupa yaitu sering kali pemanen, memotong bambu melewati batas lahan sehingga masuk ke lahan milik orang lain sehingga hal ini memicu konflik. Dinamika dalam penyelesaian konflik masih bersifat rancu dan cenderung berlarut – larut. Tujuan penelitian ini untuk mengetahui penyeban konflik, mekanisme penyelesaian konflik serta dampak yang ditimbulkan oleh konflik tapal batas. Penentuan responden menggunakan metode Snowball Sampling (bola salju) dengan jumlah 8 responden, analisis data menggunakan Metode Rapid Land Tenure Assesment (RaTA). Penyebab terjadinya konflik adalah penentuan letak batas yang umumnya bersifat rancu yakni menggunakan tanaman gose ngusu (tanaman penunjuk batas khas masyarakat kabupaten Ngada), serta pertumbuhan rumpun bambu yang masuk ke lahan milik orang lain. Mekanisme penyelesaian yang terlihat pada ke lima kasus adalah metode resolusi konflik pengaturan sendiri dan pola penyelesaian konflik dengan intervensi pihak ketiga dengan mempunyai pola yang khas yaitu penyelesaian konflik sendiri dengan pola kompetisi (competing) dan kompromi serta pengadilan perdata dan alternative dispute resolution (ADR) serta  memiliki dampak positif dan negatif pasca konflik
Implementasi Program Literasi terhadap Eskstrakkulikuler di MTsN 2 Medan
Authors: Izhra Farel , Harahap Nila Riana , Nasution Sahrina , Devianty Rina
Published: February 2024

This study aims to explain the condition of the extracurricular literacy program at MTSN 2 Medan. In addition, it also explains the effectiveness and constraints that occur in the development of this literacy program at MTSN 2 Medan. This research uses descriptive qualitative research. This study provides an overall picture of the conditions, effectiveness, and obstacles that occur in literacy programs. The results of the research show that the literacy program has not run optimally. Problems with the literacy program in learning Indonesian that occurred at MTSN 2 Medan included irrelevant learning strategies, the availability of inadequate and incomplete facilities and infrastructure, and students' low interest in reading. Sources of data in this study are documents and school implementation processes literacy program. The data in this study were collected using documentation, interviews and observation methods. The results of this study indicate that the governance of extracurricular literacy at MTSN 2 Medan is as follows (1) First, the school planning for the literacy program has been carried out by setting literacy goals for the school movement program. However, this planning has not been based on a needs analysis (2) extracurricular activities about Indonesian that have not been implemented at this school (4) the control that has been carried out is still limited to ensuring that the Thursday reading program is carried out or not. Controls to improve program quality have not been carried out. The management of the school literacy movement program needs to be managed properly, starting from the strategic planning process, organizing by giving job descriptions, implementing programs in accordance with strategic planning, and continuous evaluation
Keywords Indonesian, Ekstrakulikuler, Program Literacy
Meningkatkan Keterlibatan Siswa di Kelas Menggunakan Model Pembelajaran Think Pair Share
Authors: Arlina Arlina , Hasibuan Raudhatul Ma’wa , Syahida Nadila Aulia , Aqilla Najla Puteri , Aulaz Ibnu
Published: February 2024

There is still low student learning participation. There has not been an application of a learning model that attracts students and can foster active student learning participation and students also still find it difficult to understand the material being learned during learning. The data collection techniques used in this study were observation and documentation. Qualitative data analysis techniques to determine how much student learning participation has increased. In this Class Action Study, researchers plan 2 cycles of action using the Kemmis and Mc Taggart model research procedures. Kemmis and Mc Taggart's model research begins with planning then action, observation and reflection. The hypothesis in this study is that the use of the Think Pair Share learning model can increase student learning participationThe Think-Pair-Share strategy is a group discussion strategy which is a participatory pedagogic concept through social interaction, togetherness, and action-oriented communication explaining that TPS is a learning method developed by combining independent and group learning methods. With this TPS, students will be helped in changing the positive behavior in communication skills that occurs when they listen to each other and bring out mutual respect. Think Pair Share learning model activities can develop the thinking of individual students because of the thinking time, so that the quality of answers can also increase. By using the Think Pair Share type cooperative learning learning model, before discussing in groups, students try to think first, then discuss with their partners so that students already have material to bring in group discussions. This can be a strong factor in improving students' ability to respond to questions and foster an attitude of mutual help to each other. Thus, students will be actively involved in the learning process and can improve learning outcomes.
Keywords: Author Guidelines; Journal Al-Kharaj; Article Templates
Edukasi Pentingnya 1000 Hari Pertama Kehidupan (1000 HPK) Sebagai Langkah Pencegahan Stunting di Kelurahan Perawang Kabupaten Siak
Authors: Hasneli N Yesi , Adipa Muhammad Evan Adipa , Liana Putri Ramadlani  , Jennyfer Veronika  , Nazifah Syahirah Hasanah  , Nurul Annisya  , Nurwahyuni  , Nuryanti  , Risti Amanda Putri  , Rishatul Khoiriyah
Published: February 2024

1000 Hari Pertama Kehidupan (HPK) merupakan masa emas anak dalam pertumbuhan dan perkembangan yang berdampak bagi kualitas hidup anak hingga dewasa. Dimulai sejak 270 hari masa kehamilan hingga 730 hari setelah melahirkan. Pada masa ini, kesehatan dan kebutuhan gizi anak harus terpenuhi, untuk mencegah permasalahan gizi dan penyakit kronik pada anak. Stunting merupakan salah satu dampak buruk dari tidak terpenuhinya gizi pada 1000 HPK. Tidak hanya mempengaruhi pertumbuhan fisik yang menyebabkan anak lebih pendek dari seusianya namun juga mempengaruhi perkembangan kognitif pada anak. Tercatat bahwa angka prevalensi Stunting di Indonesia mencapai 24%, dan di wilayah Siak sekitar 22%. Untuk menurunkan prevalensi tersebut, mahasiswa KKN MBKM Keperawatan UNRI ikut bersinergi dengan melakukan penyuluhan pentingnya 1000 HPK dengan presentasi langsung dan menggunakan leaflet sebagai media. Penyuluhan ini dilakukan di wilayah kelurahan Perawang Kecamatan Tualang Kabutan Siak, Riau dengan menghadirkan kader posyandu se kelurahan yang dipercaya sebagai penggerak dan dapat menyebarluaskan informasi pada seluruh masyarakat di kelurahan Perawang. Setelah dilakukan penyuluhan, terdapat peningkatan pengetahuan warga terkait pentingnya 1000 HPK dalam pencegahan Stunting dengan hasil rata-rata pre Test 71/100 yang kemudian meningkat pada hasil rata-rata post Test 89/100. Penyuluhan ini dilakukan sebagai bentuk pengabdian terhadap masyarakat dengan harapan agar permasalahan Stunting di wilayah kelurahan Perawang dapat dicegah dan diatasi.
Atmosphären-Ästhetik
Authors: Wang Zhuofei
Published: February 2024

The aesthetic concept of atmosphere places human sensitivities under various natural and cultural conditions in the foreground of aesthetic consideration. As the first monograph to integrate an intercultural perspective into this field, “Atmosphären-Ästhetik: Die Verflochtenheit von Natur, Kunst und Kultur” is devoted to discourses and practices on aesthetic atmosphere in Western and non-Western spaces. Approaches that play a fundamental role include intercultural philosophy, body phenomenology, history of art, image science, media theory, environmental philosophy, cultural anthropology, and philosophy of language. Dimensions from the East (Daoism, Buddhism, Feng Shui teachings, etc.) are also included in this context.
Experimental Investigations on Advancements of Aluminum Alloys with Friction Stir Process
Authors: Shaik Bazani , Muralidhara Rao M. , Harinath Gowd G. , Durga Prasad B. , Ranga J.
Published: February 2024

Friction stir processing is a very promising method widely joining varieties of metals in other relatively marine, shipbuilding, automotive industries, aeronautical, and heavy machinery industries due to the following advantages, such as, low porosity, less tendency to cracking, and fewer defects. Research investigates the mechanical properties for input parameters such as welding speed, rotational speed, tilt angle, and axial force, and output parameters such as tensile strength, microhardness on advancements of aluminum alloys by using friction stir processing based on cost. Taguchi L9 used for the carrying research on experiments with trailing on parent materials in different ranges of input responses on welding speed is 60 mm/min, rotational speed 1250 rpm, tilt angle 3°, and axial force of 12 KN output responses tensile strength are 167 MPa measured on the basis of ASTM on specimens and analysis for carrying and using design of experiments and mathematical modeling, the relations with empirical process useful for the development for automated design.
Role of Phosphorus in the Photosynthetic Dark Phase Biochemical Pathways
Authors: Odoom Alex , Ofosu Wilfred
Published: February 2024

Phosphorus (P) is an essential mineral nutrient for plant growth and development, second only to nitrogen in abundance. It is frequently limited in soil, requiring the application of P-fertilizers to improve plant productivity. One critical function of P in plants is its role in the dark phase of photosynthesis, where it functions in energy storage and transfer, carbon fixation, regulation of the dark phase, and nucleotide and coenzyme biosynthesis. P is a foundational component of important molecules like ATP and essential coenzymes, which are crucial for efficient carbon fixation and energy conversion during the Calvin cycle. Sustainable P-management strategies and improved agricultural practices are necessary to optimize plant growth and ensure sustainable agricultural production in the face of P-limitations.
Atrial Fibrillation and Cardioversion Drugs
Authors: Su Taomin , Liu Pan , Shi Qin , Wang Yan , Zhou Ying
Published: February 2024

The heart is constantly and harmoniously alternating contractions and diastolic activities, and these mechanical activities are stimulated by the heart’s electrical activity. Atrial fibrillation results in changes to atrial myocytes, with early but potentially reversible alteration in ion channels. Atrial fibrillation is one of the arrhythmias characterized by mechanical dysfunction caused by uncoordinated contraction of atrium, and it is also the most common and serious arrhythmia in clinical practice, which can cause serious complications, such as hemodynamic changes and cerebral embolism. Therefore, cardioversion drugs have become a research hotspot in the field of arrhythmia. Medical treatment of atrial fibrillation includes cardioversion, control of ventricular rate, and anticoagulation. This chapter focuses on drug cardioversion.
Artificial Intelligent-Based Techniques in Solar Radiation Applications
Authors: Gidom Maysa
Published: February 2024

The evolving smart grid emerges as a response to the challenges posed by the unreliability and inefficiency of the traditional electric grid. This transformation is crucial due to issues like the aging infrastructure and the intermittency of renewable energy sources, particularly solar radiation. The smart grid is anticipated to facilitate two-way power flows and introduce innovative technologies. This study explores the impact of smart grid technologies, particularly those supported by artificial intelligence (AI), on-demand load, future energy consumption, and energy management services. The focus is on AI-based systems applied in solar energy applications, aiming to enhance efficiency and reduce costs. Various AI techniques, including neural network methods, are examined for their role in addressing challenges such as forecasting, fault diagnosis, and control in solar radiation applications. The research introduces and compares three AI models—gated recurrent unit (GRU), artificial neural network (ANN), and long short-term memory model (LSTM)—for predicting solar irradiance. The outcomes emphasize the versatility of AI, not only in solar systems but also in extending its applications to other renewable energy systems like wind and diverse fields such as security, reliability, and stability.
Freight Forwarder Role: PT. Mitsui-Soko Indonesia In The Process Of Importing Electric Motorcycle Sparepart Products (Hs Code: 8501.52) To PT. Pratama Amerta Solutions
Authors: Anugrah Putra M. Rivan
Published: February 2024

International trade has become an increasingly important factor in the global economy today. In this context, the role played by Freight Forwarders in facilitating the movement of goods between countries has become very significant. This research focuses on analyzing the role of PT. Mitsui-Soko Indonesia is a Freight Forwarder company importing electric motor spare part products classified under HS Code 8501.52, imported by PT. Pratama Amerta Solusi. This research aims to identify the contributions made by the Freight Forwarder in improving the smoothness of the import process, provide an overview of the import process, outline the documentation required for importing, and analyze the risks that could occur and their impact on the supply chain and the operational sustainability in the case study of PT. Pratama Amerta Solusi's import through the Freight Forwarder: PT. Mitsui - Soko Indonesia. The research methodology is qualitative and quantitative and employs a case study approach, focusing on the import process of PT. Pratama Amerta Solusi through PT. Mitsui Soko - Indonesia as the Freight Forwarder. Primary data were obtained through direct interviews with representatives from PT. Mitsui-Soko Indonesia, who acted as the import forwarder, while secondary data were gathered from books, national and international journals, previous research, and other credible and relevant sources. The quantitative research was conducted to obtain the magnitude of the impact and the importance of risks in PT's export and import logistics processes. Mitsui - Soko Indonesia.