bluuebunny/crossref_metadata_2025 huggingface dataset:
NARFL expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of nuclear prelamin A recognition factor-like, encoded by NARFL when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, NARFL expression was correlated with distant metastasis-free survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. NARFL may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
IGFBP3 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of insulin-like growth factor binding protein 3, encoded by IGFBP3 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, IGFBP3 expression was correlated with distant metastasis-free survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. IGFBP3 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
CYBASC3 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of cytochrome b, ascorbate dependent 3, encoded by CYBASC3 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, CYBASC3 expression was correlated with distant metastasis-free survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. CYBASC3 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Differential expression of MCF2L in cancer of the vulva.
Authors: Mamoor Shahan
Published: October 2021

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of MCF.2 cell line derived transforming sequence-like, encoded by MCF2L, in cancer of the vulva. MCF2L may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
PENGALAMAN DIGITAL KARYAWAN TERHADAP PENINGKATAN EFEKTIVITAS PERUSAHAAN PADA MASA PANDEMI COVID-19
Authors: Panggabean Angelita Nauli
Published: October 2021

Pandemi COVID-19 telah memberikan dampak bagi hampir seluruh perusahaan atau organisasi. Dengan begitu, banyak perusahaan telah menyadari bahwa agar dapat beradaptasi adalah dengan merangkul teknologi sebagai pendorong efektivitas perusahaan. Metode yang digunakan penulis adalah dengan mengumpulkan serta mempelajari jurnal-jurnal. Jurnal tersebut didapatkan dari berbagai sumber melalui internet. Dari jurnal-jurnal tersebut, dapat disimpulkan bahwa pengalaman digital karyawan merupakan unsur utama dalam mengatasi tantangan-tantangan tak terduga dalam meningkatkan efektivitas perusahaan, terutama pada masa pandemi COVID-19.
Differential expression of H2BFS in cancer of the vulva.
Authors: Mamoor Shahan
Published: October 2021

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of H2B histone family member S, encoded by H2BFS, in cancer of the vulva. H2BFS may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
Differential expression of IL13RA1 in cancer of the vulva.
Authors: Mamoor Shahan
Published: October 2021

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of interleukin 13 receptor subunit alpha 1, encoded by IL13RA1, in cancer of the vulva. IL13RA1 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
Unethical Behavior dalam Perspektif Individu dan Organisasi
Authors: Erdianti One Fitri
Published: October 2021

Perilaku tidak etis banyak ditemukan dalam berbagai setting kehidupan. Pada level organisasi, perilaku tidak etis banyak dilakukan oleh individu maupun dalam kelompok. Semakin banyak masalah yang dihadapi oleh pihak managemen dalam menjalankan kehidupan organisasi berkaitan dengan masalah etika. Banyaknya skandal yang dihadapi oleh suatu organisasi seringkali muncul disebabkan kurangnya keseimbangan dalammeletakkan/menempatkan aspek identitas etis dalam konsep diri dan perilaku anggotanya. Untuk dapat memahami bagaimana suatu perilaku tidak etis bisa dilakukan oleh individu maupun kelompok maka perlu ditinjau lebih mendalam munculnya perilaku tersebutberdasar teori mengenai moralitas. Literatur review ini bertujuan untuk menjelaskan bagaimana mekanisme individu memilih untuk melakukan perilaku tidak etis, serta bagaimana proses ini bisa ditiru oleh individu lainnya dalam persfektif moral disengangement. Dengan melakukan review yang mendalam mengenai berbagai penelitian yang relevan, maka diharapkan tercipta gambaran mengenai mekanisme terbentuknya perilaku tidak etis serta cara untuk mengantisipasi nya.
Origin and Historical Process of Modern Europe: Part One
Authors: Wang Zhiyong
Published: October 2021

Europe made the earliest contribution to modern civilisation and modernisation of Europe has long drawn attention from the academic world. This article conducts an investigation into the origin and historical process of modern Europe from a macroscopic perspective, in order to develop better understanding of the connection between European history and modern civilisation. It first illustrates the historical background against which modern Europe originated. Then it interprets the historical process of Europe’s modernisation in respect to economy, culture, politics, and technology. The outcomes and significance of Europe’s modernisation are discussed at the end. This study also reveals obvious continuity of European history and its impact on the modern world.
UKRN Checklist for an Open Research Action Plan
Authors: Darby Robert
Published: October 2021

UKRN Checklist for an Open Research Action Plan
CA2 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of carbonic anhydrase II, encoded by CA2 when comparing the primary tumors of triple negative breast cancer patients dead or alive. CA2 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Sampah Pembawa Penyakit Bagi Masyarakat
Authors: Baihaqi Mukhammad Fakhrizal
Published: October 2021

Permasalahan sampah sudah sangat umum dimata masyarakat khususnya di daerah pinggiran kota atau di daerah perdesaan. Dari sampah tersebut menimbulakan masalah salah satunya banjir yang merebak menjadi penyakit dimana menimpa masyarakat. Mulai dari gatal-gatal, diare, dbd, dll. Sebaiknya kita sebagai warga negara Indonesia yang berbudi luhur seharusnya tidak membuang sampah disungai ataupun di pinggiran sungai agar disaat musim penghujan tidak terjadi banjir yang dapat menimbulkan penyakit. Solusi yang tepat untuk permasalahan sampah sendiri juga harus diperhatikan agar tepat dan masyarakat mendapat dampak baik dari solusi tersebut.
Giới thiệu Tạp chí Kinh tế và Dự báo số 13 (573)
Authors: 子 鬼谷
Published: October 2021

Giới thiệu Tạp chí Kinh tế và Dự báo số 13 (573)Tạp chí Kinh tế và Dự báo - Bộ Kế hoạch và Đầu tư (tháng 7 năm 2014)
Manajemen Asuhan Keperawatan Pada Ny. A Dengan Kecemasan Pada Penderita Diabetes Melitus
Authors: PUTRI NAZELA NANDA
Published: October 2021

Kecemasan merupakan respon tubuh terhadap peristiwa yang terjadi, dimana respons tubuh terhadap peristiwa yang terjadi, dimana respon tubuh tersebut lebih bersifat negatif sehingga menimbulkan ketidaknyamanan bagi klien
Forschen mit archivierten Datensätzen: Wie ein Datenarchiv die Bildungsforschung vorantreibt
Authors: Eich Mario , Morina Fitore , Fischer Christian
Published: October 2021

Das Forschungsdatenzentrum (FDZ) am Institut zur Qualitätsentwicklung im Bildungswesen (IQB) archiviert die Datensätze von großen nationalen und internationalen Schulleistungsstudien sowie kleinerer lokaler Studien und stellt sie der Wissenschaft zur Verfügung. Für die Bildungsforschung liefert die Datenbank damit wahre Datens(ch)ätze, um neue Erkenntnisse zu generieren. Auch für Studierende und Promovierende werden so ambitionierte Forschungsprojekte greifbar.
SULT1A2 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2, encoded by SULT1A2 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, SULT1A2 expression was correlated with recurrence-free survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. SULT1A2 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Differential expression of SPAG9 in cancer of the vulva.
Authors: Mamoor Shahan
Published: October 2021

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of sperm associated antigen 9, encoded by SPAG9, in cancer of the vulva. SPAG9 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
PNCK expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of pregnancy up-regulated non-ubiquitously expressed CaM kinase, encoded by PNCK when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, PNCK expression was correlated with overall survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. PNCK may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Differential expression of TMEM246 in cancer of the vulva.
Authors: Mamoor Shahan
Published: October 2021

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of transmembrane protein 246, encoded by TMEM246, in cancer of the vulva. TMEM246 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
ZNF281 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of zinc finger protein 281, encoded by ZNF281 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, ZNF281 expression was correlated with distant metastasis-free survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. ZNF281 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Sentul Fruit (Sandoricum koetjape) Peel as Anti-Inflammation for Gingivitis after Scaling
Authors: Wirata I Nyoman , Agung A.A. Gede , Arini Ni Wayan , Nuratni Ni Ketut
Published: October 2021

Various herbs are used as analgesic, anti-inflammatory, anti-bacterial, anti-fungal, expectorant, anti-plaque and odorant. Sentul is an edible fruit and is also used in traditional medicinal herbs which can treat diarrhea, relieve fever, and as an anthelmintic. Sentul bark methanol extract can inhibit the growth of fungus Candida albican by 39.65%. In addition, the ethyl acetate extract of the sentul leaves also has anti-bacterial activity. The aim of this study is to determine the effect of fractionation with different types of solvents on the phytochemical compounds of Sentul fruit peel in Bali province. This research is an experimental study in a laboratory with qualitative and quantitative analysis models of chemical compounds. This research was carried out from March to August 2021. The research location was carried out in the laboratory of the Faculty of Food Technology, Udayana University. Sample criteria was old Sentul peel, about 30 kilograms. Data was collected based on the results of examinations from the Laboratory of the Faculty of Food Technology, Udayana University which subsequently analyzed qualitatively and descriptively. From several phytochemical compounds, flavonoids, saponins and tannins are aromatic hydroxyl groups that act as antibacterial. Therefore, seen from the highest levels of flavonoids, saponins and tannins, aqua fraction of Sentul ethanol extract is the best treatment with flavanoid levels of 11476.16 mg/100g QE, tannins 88.605 mg/g and saponins 6.862 mg/g.
Digital Employee Experience on Digital Transformation
Authors: Gifary Havitz Shidiq
Published: October 2021

Revolusi industri adalah istilah yang digunakan untuk menggambarkan kemajuan dan perkembangan dan industri manufaktur dunia. Hal ini juga dapat didefinisikan sebagai transformasi proses manufaktur dan manufaktur dari teknologi ke lebih modern dan teknologi yang canggih. Di antara transformasi yang telah terjadi termasuk penggunaan mesin untuk menggantikan tenaga kerja di bidang manufaktur dan produksi industri. Sampai saat ini, dunia telah mengalami beberapa revolusi industri dan sekarang menghadapi revolusi Industri Keempat (IR 4.0).
Hak Mendapatkan Vitamin di Masa Covid 18 Yasmin Syahrani, Muhammad Ali Sodik IIK STRADA INDONESIA
Authors: Syahrani Yasmin
Published: October 2021

World Health Organization (WHO) mengumumkan pada Desember 2019 tentang wabah preumonia coronavirus di Wuhan, provinsi Hubet(China). Dilaporkan pada 05 Oktober 2021 4.221.610 kasus. Coronavirus adalah virus RNA dari genus Betacoronavirus, yaitu distribusi pada burung , manusia, dan mamalia lainnya. WHO telah menamai penyakit coronavirus baru ini sebagai COVID 19. Saat ini, sudah ada vaksin atau obat antivirus khusus untuk penyakit COVID 19. Lebih dari 80 uji klinis telah diluncurkan untuk menguji pengobatan coronavirus, termasuk beberapa obat reposisi unutuk COVID 19 . salah satu obar reposisi yaitu vitamin. Vitamin, komponen penting dari sistem antioksidan seluler bermanfaat bagi manajemen perawatan kritis. Vitamin juga dapat membunuh dan mencegah replikasi virus . Beberapa penelitian menunjukan pemberian vitamin secara oral dan intravena dapat mengurangi peningkatan risiko komplikasi, mengurangi tingkat keparahan, mengatasi gejala maupun meningkatkan prognosis dengan COVID 19.
BAHAYA PENDERITA DIABETES MELITUS TERPAPAR COVID-19 PADA MASA PANDEMI SEKARANG
Authors: timumun wisda widianti r
Published: October 2021

Penyakit diabetes melitus (DM) merupakan penyakit kronis menyebabkan gangguan metabolisme dengan meningkatnya kadar gula dalam darah karena insufisien fungsi insulin. Pada pasien penderita diabetes melitus bisa terkena penyakit lain yang di sebut komplikasi seperti penyakit jantung dan gagal ginjal, di tambah dengan masalah sekarang penderita diabetes melitus juga terancam terpapar virus corona (covid-19) dan lambat laun akan dapat menyebabkan terjadinya kematian pada penderita komplikasi diabetes melitus. Informasi yang di butuhkan untuk menguatkan dan menberikan solusi sangat penting agar bisa menjalani hidup dimasa pandemi ini. Pada pasein penderita diabetes melitus diharapkan memiliki perilaku yang sehat dan rajin berolahraga di rumah demi menjaga stamina tubuh dan mengikuti pengobatan yang dilakukan selama ini.Kata kunci : diabetes melitus, covid-19.
Differential expression of FHL1 in cancer of the vulva.
Authors: Mamoor Shahan
Published: October 2021

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of four-and-a-half LIM domains 1, encoded by FHL1, in cancer of the vulva. FHL1 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
PENTINGNYA KUALITAS E-SERVICE DAN CITRA PERUSAHAAN TERHADAP KEPUASAN KONSUMEN
Authors: Panggabean Angelita Nauli
Published: October 2021

Perkembangan teknologi telah memberikan tantangan baru bagi banyak perusahaan. Perusahaan perlu berpikir dan mengetahui strategi yang cepat dan tepat demi tetap bertahan dan mampu bersaing di pasar. Namun, sifat pelanggan yang berubah-ubah, sangat bervariasi, serta tidak dapat diprediksi pun menjadi tantangan bagi perusahaan itu sendiri. Kualitas pelayanan dan citra perusahaan adalah kunci dan faktor penting yang dapat menentukan keberhasilan perusahaan dalam memberikan kepuasan pelanggan. Dengan demikian, karya tulis ini bertujuan untuk mengetahui seberapa penting kualitas layanan dan citra perusahaan terhadap kepuasan pelanggan.
RASGRP1 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of RAS guanyl releasing protein 1 (calcium and DAG-regulated), encoded by RASGRP1 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, RASGRP1 expression was correlated with overall survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. RASGRP1 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
partisipasi masyarakat dalam musrembang di desa bulo kecamatan panca rijang kabupaten sidenreng rappang
Authors: nurdin muhammad yusril
Published: October 2021

Tujuan penelitian untuk mengetahui partisipasi masyarakat desa dalam penyusuan rencana pembangunan desa Pajalele dapat menjadi salah satu tolak ukur sejauh mana desa tersebut mengembangkan nilai-nilai tata kelola pemerintahan desa yang baik dalam roda pemerintahanya. Partisipasi masyarakat dalam Musyawarah Perencanaan Pembangunan (Musrenbang) di Desa bulo Kecamatan panca rijang Kabupaten Sidenreng Rappang. Jenis pengumpulan data ini adalah metode deskriptif dengan pendekatan kualitatif. Populasi penelitian ini adalah seluruh masyarakat di Desa bulo Kecamatan panca rijang Kabupaten Sidenreng Rappang dan sampel yaitu masyarakat yang dianggap banyak mengetahui terhadap masalah yang dihadapi dan diharapkan agar responden yang dipilih mewakili populasi yaitu 80 orang. Penelitihan ini menunjukkan bahwa Pastisipasi Musyawarah Dalam Perencanaan Pembangunan (Musrenbang) di Desa bulo Kecamatan panca rijang Kabupaten Sidenreng Rappang berada pada kategori baik, partisipasi masyarakat dalam musyawarah perencanaan pembangunan berada pada kategori sangat baik, dan Faktor-faktor yang mempengaruhi peranan pemerintah desa dan partisipasi masyarakat dalam Musyawarah Perencanaan Pembangunan berada pada kategori baikKata Kunci : Partisipasi Masyarakat;Musrenbang
The Influence of Training Methods and Students Work Ethos on Work Competency
Authors: Lunarny Eny , Wachidi  , Alexon  , Sapri Johanes
Published: October 2021

The purpose of this study was to analyze the effect of training methods and work ethic on students' work competencies. The focus of teaching implementation is observed using two training methods, namely: on the job training method using internship training and simulasi method using simulation. The initial work ethic of students is limited to low and high categories. This type of research is a quasi-experimental with a 2 × 2 factorial design. The research population is all students of class XI of the Hospitality Accommodation Department at SMK Negeri 7 Bengkulu City, totaling 123 people. The sample was selected using the intact group technique from four classes selected to be two learning classes as the experimental group. The selected class is drawn by lottery to determine the treatment of the internship training and simulasi methods. Each treatment group was grouped based on low work ethic and high work ethic. The research instrument is a work competency assessment sheet and student work ethic. The data analysis technique used is 2-way analysis of variance. The results of the study can be concluded that: (1) the average work competence of students using the internship training method is higher than those using the simulation method. (2) The average work competence of students who have a high work ethic is higher than students with a low work ethic. (3) There is an interaction effect between training methods and work ethic on the work competence of students. (4) Students with a high work ethic who take part in the internship training method have higher work competencies compared to the simulation method. (5) Students with a low work ethic who take part in the internship training method have lower work competencies than those using the simulation method.
Differential expression of EDN3 in cancer of the vulva.
Authors: Mamoor Shahan
Published: October 2021

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of endothelin 3, encoded by EDN3, in cancer of the vulva. EDN3 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
Differential expression of TGFBR3 in cancer of the vulva.
Authors: Mamoor Shahan
Published: October 2021

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of transforming growth factor beta receptor 3, encoded by TGFBR3, in cancer of the vulva. TGFBR3 may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
Measuring Air Quality Over Denpasar City Indonesia in 2021
Authors: Suyasa I Nyoman Gede , Marwati Ni Made , Rusminingsih Ni Ketut
Published: October 2021

The imbalance number of rapid vehicles with transportation facilities has become the problem. In Denpasar, Indonesia, the congestion during peak hours happens so often. Based on the department of transportation in Denpasar, Indonesia, the number of vehicle ownership in Bali is 4.1 million in condition with a ratio of one resident to one vehicle with the current population of Bali Province approximately 4.2 million. Our study aim to measure the air chemical parameters of CO, O3, SO2, NO2 and the physical parameters of the noise level. The research population is the atmosphere environment in the Denpasar City area. The research sample points were taken in the city center and the outskirts of Denpasar, with a total of 27 sample points. We employed impinge to get the airborne chemical gases and it is all analyzed with a spectrophotometer. We used a sound level meter to measure the ambient noise level. The data analysis was performed with free sample t test. The average ambient air chemistry obtained CO 517.34 µgr/Nm3, O3 0.17 µgr/Nm3, SO2 61.46 µgr/Nm3 and NO2 2.51 µgr/Nm3 and an average noise level 67.66 dBA. The number has found below the requirements Environmental Quality Standards and Environmental Damage Standard Criteria by Bali Governor. There is a difference in the mean parameters of CO, SO2, NO2 and ambient noise level in the downtown area. The average CO is 757.15 µgr/Nm3, SO2 67.60 µgr/Nm3, NO2 3.77 µgr/Nm3 and the noise level is 68.53 dBA with Denpasar outskirts mean CO 217.57 µgr/Nm3, SO2 53.79 µgr/Nm3, NO2 0.95 µgr/Nm3 and noise level 66.57 dBA. There is no difference in the average ambient O3 in the city center area with an average of 0.22 µgr/Nm3 with the outskirts of Denpasar an average of 0.11 µgr/Nm3.
Perioperative Anesthetic Management in Preterm 12 Days Infants with Giant Meningoencephalocele at Mid Occipital and Secondary Trigonocephaly
Authors: Saputra Kirby , Halimi Radian Ahmad
Published: October 2021

Introduction: A meningoencephalocele is herniation of neural element along with meninges through a congenital defect in cranium. The incidence of encephalocele is approximately 1/5000 live births; occipital encephalocele is more common in females than males. It is called as giant meningoencephalocele when the head is smaller than the meningoencephalocele. These giant meningoencephaloceles harbor a large amount of cerebrospinal fluid (CSF) and brain tissue, so there occur various surgical challenges and anesthetic challenges in positioning and intubation. Case: A 12 days neonate was consulted to the neurosurgery department with complaints of large swelling over the back of head and difficulty in feeding. She was diagnosed with ventriculomegaly and meningoencephalocele since 32-33 pregnancy. The swelling was small at the time of birth, but it gradually increased in size. The child was born by section caesarean because of fetal distress and meningoenchepalocele. The neonate current weight was 3.195 grams with Post Conceptional Age (PCA) 35-36 weeks. On examination, the patient large spherical swelling was present over occipital region and there was no head control. The patient was active, conscious with no impression of focal neurological deficit. Systemic examination was unremarkable. The head circumference was 30 cm and circumference of occipital swelling was 40 cm. Potential problems in this patient include preoperative preparation and optimization of general condition, difficulty in positioning the patient, difficult airway (intubation), periodic apnea and potential hemodynamic disturbances and a sudden decrease in intracranial pressure during cele resection. Conclusion: Perioperative management in this case started from preoperative to postoperative evaluation. Preoperative preparation in anticipation of airway difficulties and communication with the operator is very important. Appropriate anesthetic techniques should aim to maintain stable hemodynamics and oxygenation and prevent a sudden increase or decrease in intracranial pressure.
Social media as a dissemination and knowledge translation strategy among health professions educators: A scoping review protocol
Authors: Giroux Catherine M. , Sikora Lindsey , Bussières André , Ellaway Rachel , Thomas Aliki
Published: October 2021

COVID-19 has arguably affected health professions education. Educators have rapidly transitioned to delivering educational sessions remotely while clinical training opportunities have been canceled, postponed or modified. Recent commentaries and reports have recommended leveraging existing online educational resources like pre-recorded lectures, blogs, and podcasts to facilitate health professions remote learning. However, the feasibility of doing so remains uncertain and the impacts thereof are also a matter for concern. In this work, we present our critical scoping review protocol. We aim to explore whether and how health professions educators have used social media as a mechanism of dissemination and knowledge translation to support evidence informed HPE approaches in the peer-reviewed and grey literature, drawing on Engeström's Activity Theory as a guiding theoretical framework.
Hak masyarakat mendapatkan kecukupan gizi
Authors: Na'u Janilda
Published: October 2021

Tindakan penyuluhan diberlakukan kepada orang-orang kaya atau orang-orang yang masih mampu memenuhi kebutuhan hidupnya dengan baik namun karena kurangnya pengetahuan tentang pentingnya gizi dan nutrisi serta pola asuh yang salah mereka menderita kurang gizi atau bahkan gizi buruk. Oleh karena itu bagi mereka yang menderita kurang gizi maupun gizi buruk akan diberikan suatu penyuluhan dalam bentuk pendidikan diluar bangku sekolah atau sosialisasi untuk merubah pola perilaku dan pola pikir masyarakat dalam hal-hal yang berhubungan dengan gizi. Sedangkan tindakan pemulihan diberlakukan kepada orang-orang yang mengalami gizi buruk yang dilatarbelakangi oleh faktor kemiskinan, jadi dapat dikatakan bahwa tindakan pemulihan ini diberlakukan untuk keluarga yang kurang mampu atau miskin. Dalam tindakan pemulihan ini anak yang menderita gizi buruk akan diberi perawatan khusus selama 90 hari dan diberikan makanan tambahan secara gratis. Masalah gizi buruk tentunya sangat disayangkan karena kita ketahui anak merupakan calon generasi penerus bangsa. Oleh karena itu, upaya pemeliharaan kesehatan bayi dan anak harus ditujukan untuk mempersiapkan generasi yang akan datang yang sehat, cerdas, dan berkualitas serta untuk menurunkan angka kematian bayi dan anak. Berkaitan dengan hal tersebut maka anak yang dilahirkan wajib dibesarkan dan diasuh secara bertanggung jawab sehingga memungkinkan anak tumbuh dan berkembang secara sehat dan optimal. Upaya pemeliharaan kesehatan anak dilakukan sejak anak masih dalam kandungan, dilahirkan, setelah dilahirkan, dan sampai berusia 18 (delapan belas) tahun.
Chương 1 Tổng quan marketing (marketing overview)
Authors: Tung Dao Duy
Published: October 2021

This first chapter introduces you to the basic concepts of marketing. Simply put, marketing is engaging customers and managing profitable customer relationships. The aim of marketing is to create value for customers in order to capture value from customers in return. After that, I discuss the five steps in the marketing process—from understanding customer needs, to designing customer value–driven marketing strategies and integrated marketing programs, to building customer relationships and capturing value for the firm.
LYZL2 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of lysozyme-like 2, encoded by LYZL2 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, LYZL2 expression was correlated with overall survival in patients with breast cancer. LYZL2 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Context Analysis of Non-intellective Correlates affecting Future Educators’ Sociolinguistic Competence
Authors: Tejada Kristoffer Conrad M.
Published: October 2021

The study investigated the non-intellective correlates affecting the sociolinguistic competence of teacher education students, with a focus on the analysis of their contexts relative to social experiences, language attitude, and use of linguistic forms in different situations. It also determined the common difficulties they experience in the use of English in both oral and written forms. Descriptive mixed methods were utilized, with a validated questionnaire serving as primary instrument to gather relevant data from 331 teacher education students from different fields of specialization. Focus group discussions were conducted to activate the students’ awareness of non-intellective correlates and extract emerging issues in language use. The analysis of the quantitative data together with the coded and categorized transcriptions revealed that while the students generally have a positive attitude towards the use of the English language, they rarely use varied linguistic forms adaptive to different social contexts, implying the need to work on their adaptive capacities in using English for various purposes. Most of the issues they encounter are psychological and socio-physical in nature, while limited vocabulary, over-consciousness in grammar use, and lack of confidence affect their skills most. It was recommended that contextualized activities be developed for integration in the communication courses to highlight the authentic use of language in different social contexts.
Differential expression of GPD1L in cancer of the vulva.
Authors: Mamoor Shahan
Published: October 2021

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of glycerol-3-phosphate dehydrogenase 1-like, encoded by GPD1L, in cancer of the vulva. GPD1L may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
MAP6 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of microtubule-associated protein 6, encoded by MAP6 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, MAP6 expression was correlated with distant metastasis-free survival in basal subtype breast cancer, a molecular subtype sharing significant overlap with triple negative breast cancer. MAP6 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
TTC5 expression associates with survival in triple negative breast cancer.
Authors: Mamoor Shahan
Published: October 2021

We mined published microarray data (1) to understand the most significant gene expression differences in the tumors of triple negative breast cancer patients based on survival following treatment: dead or alive. We observed significant transcriptome-wide differential expression of tetratricopeptide repeat domain 5, encoded by TTC5 when comparing the primary tumors of triple negative breast cancer patients dead or alive. Importantly, TTC5 expression was correlated with recurrence-free survival in patients with breast cancer. TTC5 may be of relevance as a biomarker or as a molecule of interest in understanding the etiology or progression of triple negative breast cancer.
Differential expression of NFIB in cancer of the vulva.
Authors: Mamoor Shahan
Published: October 2021

In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of nuclear factor I B, encoded by NFIB, in cancer of the vulva. NFIB may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).
Reexamining the “Brain Drain” Effect: Does Ward et al. (2017) Replicate?
Authors: Ruiz Pardo Ana Cecilia , Minda John Paul
Published: October 2021

The present study was a pre-registered direct replication of Ward et al.’s (2017) second experiment (OSF pre-registration found at: https://osf.io/5fq4r). This replication assigned both smartphone location (on desk, in pocket/bag, or outside of the testing room) and smartphone power (on, or off) for a total of six conditions. Participants completed an automated operation span (OSpan) task, a cue-dependent go/no-go task, and the smartphone attachment and dependency inventory. It was hypothesized that performance on an attention-demanding task (i.e., the OSpan task) would be worse for those in closer proximity to their smartphone (on desk) and that those with greater smartphone attachment and dependency would have a larger “brain drain” effect. Using the same tasks and conditions as in Ward et al.’s (2017) second experiment, the present study found that the “brain drain” effect did not replicate: there was no difference between smartphone location conditions on performance on either the o-span task or the go/no-go task. These findings demonstrate that the mere presence of one’s smartphone may not be enough to affect cognitive performance. Understanding these effects is crucial in a time where smartphones are a basic necessity.
ERICA (Stopping Child Maltreatment through Pan-European Multiprofessional Training Programme: Early Child Protection Work with Families at Risk) Training Programme Design
Authors: Zlatkute Giedre , Bekaert Sarah , Appleton Jane , Paavilainen Eija , Schecke Henrike , Specka Michael , Scherbaum Norbert , Jouet Emmanuelle , Zabłocka-Żytka Lidia , Wozniak-Prus Malgorzata , Czabala Czeslaw , Kluczyńska Sylwia , Bachi Bianca , Bartoli Francesco , Carrà Giuseppe , Cioni Riccardo Matteo , Crocamo Cristina , Rantanen Heidi , Kaunonen Marja , Nieminen Irja , Roe Laura , Keenan Katherine , Viganò Giovanni , Baldacchino Alexander
Published: October 2021

This paper describes the design and development of the ERICA (Stopping Child Maltreatment through a Pan European Multiprofessional Training Programme: Early Child Protection Work with Families at Risk) training programme. ERICA project was funded by the Rights, Equality and Citizenship Funding programme of the European Commission (European Commission 2019-2021), and has an overarching aim to develop, pilot and evaluate a Europe wide training programme in prevention, assessment, support and referral in relation to child maltreatment. It is a pan-European partnership with collaborators from Finland, England, Scotland, France, Germany, Italy and Poland. ERICA project proposes an integrated strategy to deal with child maltreatment risk and child maltreatment that consists of a multidisciplinary training across services and professional profiles, plus the design and promotion of a community engagement strategy, to build protective factors around families at risk and families suffering from child maltreatment.
Co-DAS: Development and Evaluation of Co-Driver Assistance System Concepts to Reduce Passenger Discomfort
Authors: Ittner Sandra , Muehlbacher Dominik , Vollrath Mark , Weisswange Thomas H.
Published: October 2021

The front seat passenger is often neglected when developing support systems for cars. There exist few examples of systems that provide information or interaction possibilities specifically to those passengers. Previous research indicated that the passive role of the passenger can frequently lead to a feeling of discomfort, potentially caused by missing information and missing control with respect to the driving situation. This paper proposes a variety of prototypical passenger assistance systems that target different aspects of the cognitive processes which could cause the feeling of discomfort. In a simulator study with N = 40 participants, these systems were investigated with respect to their influence on measures of discomfort. Participants experienced different car following and braking scenarios on the highway with different time headways, with and without one of the passenger assistance systems. Based on the subjective measures, three systems were identified as particularly useful in reducing discomfort. For the best of these proposals, more than 63 % of the passengers confirmed the usefulness of the approach and reported an interest in using it in their vehicle. This demonstrates significant opportunities to improve the everyday driving experience beyond classical assistant systems by explicitly taking into account the needs of the passengers.
What Do People Say Is the Most Important Reason to Protect Nature: An Analysis of Pro-Environmental Motives Across 11 Countries
Authors: Gustafson Abel , Pace Amanda , Singh Shelby , Goldberg Matthew H.
Published: October 2021

Using open-ended responses from 5,297 interviews across 11 countries, this study reports what people say are the most important reasons to protect nature. Overall, and in some individual countries (e.g., Brazil, China, South Africa, South Korea, United States), the most frequently stated reason was an anthropocentric motive of ensuring human health and survival. But in some countries (e.g., Kenya, United Kingdom, Indonesia), ecocentric and altruistic motives—such as maintaining balance in nature’s delicate interconnected system or protecting nature for future generations—were more common.
The Relationship Between Cognitive Reappraisal and Psychological Well-Being during Early Adolescence: A Scoping Review Protocol
Authors: Shum Christopher , Dockray Samantha , McMahon Jennifer
Published: October 2021

Introduction: Early adolescence has been defined as a sensitive developmental period for psychological well-being. As children transition into early adolescence, they begin to regulate their emotions independently of their caregivers and they integrate cognitive processes into their emotion regulation. Brain maturation during early adolescence facilitates the emotion regulation strategy of cognitive reappraisal, whereby adolescents develop the ability to change how they think about an emotion-evoking stimulus to then change how they feel in any given moment. The development of cognitive reappraisal has been found to improve psychological well-being among adults. However, there has been a lack of empirical research identifying the relationship between cognitive reappraisal and psychological well-being among early adolescents. As such, there is a need to highlight gaps in knowledge and to identify and summarise the key findings that have examined cognitive reappraisal and psychological well-being during early adolescence.Methods: The current scoping review will adhere to the guidelines of Arksey and O’Malleys’ scoping review methodology (2005). Five research databases (PsychArticles, PsychINFO, EBSCO, ERIC and Education Source) and two unpublished/grey literature databases (NICE-UK and OpenGrey) will be used to identify relevant literature. Two independent reviewers will then screen the identified studies in accordance with pre-specified eligibility criteria and extract data based on evidence source characteristics, and details regarding the relationship between cognitive reappraisal and psychological well-being. The data will then be charted, organised into main findings and presented as a narrative summary.Discussion: The findings from the scoping review will give an overview of the relationship between cognitive reappraisal and psychological well-being among early adolescents and provide future directions to account for gaps in the research. The results will be disseminated through journals, conferences, blogs and podcasts related to adolescent development, adolescent health and emotion regulation.
A Social Gradient of Cortical Thickness Relative to Age in Adolescence: Relations Among Neighborhood Socioeconomic Disadvantage, Advanced Cortical Thinning, and Depressive Symptoms
Authors: Miller Jonas , Lopez vanessa , Buthmann Jessica L. , Garcia Jordan , Gotlib Ian
Published: October 2021

Background: Mental and physical health are affected by family and neighborhood socioeconomic status (SES). Accelerated biological aging in the context of lower SES is one mechanism that might contribute to underlying health disparities; few studies, however, have considered neighborhood SES in relation to neural markers of biological aging in adolescents. Methods: In 120 adolescents 13-18 years of age, we examined family and neighborhood SES in relation to biological aging in the brain, indexed by cortical thickness relative to chronological age. We also examined whether advanced cortical thinning relative to age was related to depressive symptoms and explored regions of interest.Results: Neighborhood socioeconomic disadvantage was uniquely associated with advanced cortical thinning in the left hemisphere (=-.20), which was related to more severe depressive symptoms (=-.33). In contrast, family income-to-needs was not significantly associated with cortical thickness age after controlling for relevant covariates. In exploratory, covariate-adjusted analyses of cortical thickness relative to age at the regional level, neighborhood socioeconomic disadvantage was associated with advanced cortical thinning in the left superior frontal gyrus (=-.27), fusiform gyrus (=-.20), and insula (=-.21). Of these regions, only advanced cortical thinning in the left superior frontal gyrus was associated with more severe depressive symptoms (=-.18). Conclusion: Our findings provide evidence for a social gradient of accelerated biological aging at the neural level during adolescence. Adolescents living in less advantaged communities have a thinner left hemisphere cortex than expected given their chronological age. Advanced cortical thinning may increase risk for depression in adolescence.