bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Regional Inspectorate of Samarinda City In Maintaining Unqualified Opinion
Authors: Hidayah Kemal , Wismono Fani Heru , Kusumaningrum Mayahayati , Amarullah Rustan
Published: December 2019

Local government will gain prestige if the examination accounting performance of local government gets an unqualified opinion (WTP) from BPK. The opinion shows that the performance of the local government is in accordance with the principle of accountability. However, not all of local governments be able to achieve the predicate of WTP, because indeed to get it is not easy. Therefore, it is necessary for agencies to be the leading sector to assist all OPDs in preparing the accounting performance reports of each agency before the BPK enters, and the agency is the Inspectorate. This research aims to describe the role of Inspectorate in Samarinda City in defending the WTP predicate.Using a qualitative approach and descriptive analysis, in-depth interviews were conducted to officials from the Inspectorate and Regional Financial Management Agency (BPKAD) to validate the data. The conclusions obtained were that the Inspectorate had several roles in maintaining the WTP predicates in Samarinda City, namely: the role of facilitation, guidance, and verification for the OPD, the coordination role for the DPRD, the role of coordination and facilitation for the BPK, and the role of reporting and input to regional heads to take further policy steps.
Keywords: Inspectorate’s Role, Supervision, Local Government Performance, Unqualified Opinion
Abstrak
Mendapatkan hasil pemeriksaan kinerja pemerintah daerah dengan predikat opini Wajar Tanpa Pengecualian (WTP) dari BPK merupakan suatu prestise tersendiri bagi daerah. Predikat inilah yang menunjukkan bahwa laporan kinerja keuangan pemerintah daerah sudah sesuai dengan prinsip akuntabilitas. Namun demikian belum semua daerah mampu mencapai derajat WTP, karena memang untuk mendapatkannya tidak mudah. Oleh karenanya perlu instansi yang menjadi leading sector untuk mendampingi seluruh OPD dalam menyusun laporan kinerja keuangan masing-masing instansi sebelum BPK masuk, dan instansi tersebut adalah Inspektorat. Penelitian ini mencoba memberikan gambaran bagaimana peran Inspektorat Daerah Kota Samarinda dalam mendukung predikat WTP yang dalam beberapa tahun ini telah diraih oleh Kota Samarinda. Menggunakan pendekatan kualitatif dan analisis deskriptif, dilakukan in-depth interview kepada para pejabat dan stakeholder dari Inspektorat serta Badan Pengelola Keuangan Daerah (BPKAD) agar dapat dilakukan kroscek terhadap data yang ada. Kesimpulan yang diperoleh adalah Inspektorat memiliki beberapa peran dalam mempertahankan predikat WTP di Kota Samarinda, antara lain peran fasilitasi, pembinaan, serta verfikasi bagi OPD, peran koordinasi bagi DPRD, peran koordinasi dan fasilitasi bagi BPK, dan peran pemberi bahan laporan dan masukan bagi kepala daerah untuk mengambil langkah kebijakan lebih lanjut.
Kata Kunci: Peran Inspektorat, Pengawasan, Kinerja Pemerintah Daerah, WTP
Atopic dermatitis; impact on the quality of life and patients attitude toward its management
Authors: Alshareef Bayan , Alghamdi Sundos , Harfi Shoaa , Abuaziz Roayad , Alkuwaiti Sahar , Asiri Mohammed , Alanazi Mohammed , Almaghrabi Roaa
Published: December 2019

Atopic dermatitis is an inflammatory chronic skin disease that affects both adults and children. It is a serious condition in adults, and it affects different areas of the body in adults compared to children. The patients with skin disease experience a wide range of symptoms that affect their lives. The current study was aimed at reviewing atopic dermatitis and its relation to the patients quality of life (QOL) and attitude. The online databases PubMed, Google Scholar, and social research media Research gate were used to perform a literature search for publications published between 2001 and 2018, without any date or language restrictions. We used a combination of relevant search terms and independently identified 40 articles initially selected based on the title and abstract, there were 20 articles included in this review, finally after further screening and filtration. Atopic dermatitis was found to have a negative impact on the QOL of both patients and their families.
Smoking practices of parents regarding passive smoke exposure of their preschool children: a cross-sectional study
Authors: Dahlawi Marwa , Almasoudi Haneen , Alfaifi Malak , Alkaram Essra , Sulaimani Razan , Alanka Mohammed
Published: December 2019

Background: Secondhand smoking confers risk to childrens health. Young children living with smoker parents are exposed to unacceptable health hazards. This study was done to assess the smoking practices of parents regarding passive smoke exposure of their preschool children in Saudi Arabia.
Methodology: This cross-sectional study was conducted in Saudi Arabia in 2019 on parents of Saudi children in preschool. The questions referred to the age of the child, the gender of parents, presence of smokers in the household, and history of respiratory symptoms, respiratory morbidity, and hospitalization for respiratory causes.
Results: The overall prevalence of smoking among parents was 50%. The majority of them were males (70%). Age and gender of parents had no significant effect on passive smoke exposure in children (p > 0.05). However, the educational level of parents and the number of rooms in the house were significant factors correlated with passive smoke exposure in children (p < 0.05).
Conclusion: The low socioeconomic status and low education were identified as risk factors for childrens exposure to secondhand smoking.
DESAIN LOGO KERUPUK MIE “KEMBANG MATAHARI” SEBAGAI UPAYA MENINGKATKAN CITRA
Authors: Purnengsih Iis , Rukiah Yayah , Pratama Dendi , Dawami Angga Kusuma
Published: December 2019

Kerupuk Mie merek “Kembang Matahari” adalah salah satu produk unggulan daerah di Kabupaten Bogor yang berdiri sejak tahun 1977. Pemasaran yang kurang maksimal membuat Kerupuk Mie “Kembang Matahari” banyak ditiru, dan akhirnya menurunkan penjualannya. Perusahaan Kerupuk Mie “Kembang Matahari” harus bekerja keras untuk meningkatkan omzet penjualan. Dalam hal ini, salah satu upaya untuk meningkatkan omzet penjualan adalah dengan membuat desain logo yang menarik. Dan perusahaan Kerupuk Mie “Kembang Matahari” harus semaksimal mungkin untuk membentuk sebuah identitas yang kuat pada desain kemasan. Dengan adanya identitas yang kuat tersebut, sebuah perusahaan akan menjadi lebih dikenal oleh konsumen. Tujuan dari perancangan desain kemasan Kerupuk Mie”Kembang Matahari” adalah untuk menghasilkan desain kemasan dan logo Kerupuk Mie “Kembang Matahari”. Perancangan akan dilaksanakan dengan metode penelitian kualitatif secara deskriptif dengan melakukan observasi, wawancara, dokumentasi, studi literature dan studi kompetitor untuk mendapatkan data sebagai konsep perancangan desain kemasan Kerupuk Mie “Kembang Matahari”. Analisis data dengan menggunakan beberapa tahapan yaitu reduksi data, penyajian data, dan verifikasi kesimpulan. Setelah menganalisis data, ditemukan sebuah kata kunci “Asli” untuk perancangan desain logo . Konsep “Asli” dalam perancangan desain logo ini bermakna sesuatu yang bisa dipercaya. Hasil dari perancangan desain logo ini adalah upaya untuk meningkatkan citra dari logo Kerupuk Mie “Kembang Matahari”. The "Kembang Matahari" brand of Noodle Crackers is one of many flagship regional products in Bogor Regency which was established in 1977. Inadequate marketing of "Kembang Matahari" Noodle Crackers opened doors for imitation products, and ultimately reduced sales. "Kembang Matahari" Noodle Crackers Company must work hard to increase sales turnover. In this case, one of the efforts to increase sales turnover is by coming up with an attractive logo design and "Kembang Matahari" Noodle Crackers company must do its best to form a strong identity on packaging design. With this strong identity, the company will become better known by consumers. The purpose of designing "Kembang Matahari" Noodle Crackers packaging design is to produce both the "Kembang Matahari" Noodle Crackers packaging and logo design. The design will be carried out using descriptive qualitative research method by conducting observations, interviews, documentation, literature studies and competitor studies to obtain data as a design concept for the "Kembang Matahari" Noodle Crackers packaging design. Data analysis was conducted through several stages, from data reduction, data presentation, to verification of conclusions. After analyzing the data, the keyword "Original" was used for designing the logo. The concept of "Original" in the design of this logo means that it can be trusted. The result of this logo design is an effort to improve the image of the "Kembang Matahari" Noodle Cracker logo.
PENGARUH ART THERAPY TERHADAP PREGNANCY-SPECIFIC DISTRESS PADA PEREMPUAN DEWASA AWAL YANG MENGALAMI KEHAMILAN PERTAMA
Authors: Caestara Anastasia Nadya , Satiadarma Monty P. , Risnawaty Widya
Published: December 2019

Pregnancy-specific distress (PSD) yang merupakan perasaan khawatir atau terganggu terkait gejala fisik, perubahan bentuk tubuh, perubahan hubungan interpersonal dengan orang lain, proses persalinan, kesehatan bayi, cara merawat bayi, dan risiko dari perawatan medis yang dilakukan pada masa kehamilan. PSD dapat diatasi dengan art therapy dalam bentuk menggambar dan melukis agar partisipan dapat mengekspresikan perasaan negatif yang menyebabkan PSD. Tujuan penelitian ini adalah membuktikan apakah art therapy dengan menggambar dan melukis berpengaruh dalam menurunkan PSD. Karakteristik partisipan penelitian adalah perempuan dewasa awal yang sedang hamil pertama kali, memiliki usia kehamilan trimester pertama, dan mengalami PSD yang diukur dengan alat ukur Revised Prenatal Distress Questionnaire (NuPDQ). Penelitian ini menggunakan pendekatan mix method dengan desain one-group pretest posttest design. Teknik sampling yang digunakan adalah purposive sampling. Jumlah sampel pada penelitian ini adalah 6 orang partisipan. Hasil penelitian menunjukkan art therapy efektif untuk menurunkan PSD pada seluruh partisipan. Art therapy dapat membantu partisipan mengekspresikan emosi dengan menggambar dan melukis. Pregnancy-specific distress (PSD) is a feeling of worry or disturbance related to physical symptoms, changes in body shape, changes in interpersonal relationships with others, labor, baby's health, how to care for babies, and the risk of medical care during pregnancy. PSD can be overcome with art therapy in the form of drawing and painting so that participants can express negative feelings that cause PSD. The purpose of this study is to prove whether art therapy by drawing and painting has an effect in reducing PSD. Characteristics of study participants were early adult women who were expecting for the first time, had gone through first trimester gestational age, and experienced PSD as measured by the Revised Prenatal Distress Questionnaire (NuPDQ). This research utilized mix method approach with one-group pretest posttest design. The sampling technique used was purposive sampling. The number of samples in this study were 6 participants. The result showed that art therapy was effective in reducing PSD in all participants. Art therapy can help participants express emotions by drawing and painting.
PENGGUNAAN DRONE PADA PELIPUTAN BERITA TELEVISI (Perspektif Wartawan Televisi Terhadap Etika Peliputan Menggunakan Drone)
Authors: Yoedtadi Moehammad Gafar
Published: December 2019

Saat ini pesawat drone telah menjadi perlengkapan wajib dalam peliputan berita. Pesawat drone memberikan kemudahan dan penghematan bagi media pemberitaan untuk mengambil gambar dengan sudut pengambilan dari angkasa. Dengan drone media massa, terutama televisi dapat memperkaya visual dalam beritanya. Namun dengan segala kelebihannya, penggunaan pesawat drone tetap harus mempertimbangkan etika jurnalistik. Antara lain persoalan privasi dan izin peliputan. Penelitian ini hendak menggali perspektif wartawan terhadap etika jurnalistik ketika melakukan peliputan dengan memanfaatkan pesawat drone. Penelitian ini menggunakan perspektif kualitatif dengan metode fenomenologi. Penelitian ini melibatkan empat orang wartawan drone (drone journalist) dari dua stasiun televisi. Wartawan yang dapat mengemudikan drone belum banyak. Masing-masing televisi hanya memiliki empat orang wartawan. Dari empat wartawan drone, peneliti mengambil partisipan dua orang wartawan drone yang telah bersertifikat dan berpengalaman pada masing-masing televisi. Hasil penelitian menunjukkan bahwa tidak semua wartawan drone memahami dengan benar etika peliputan menggunakan drone. Tututan tugas untuk mendapatkan gambar yang bagus menyebabkan para wartawan drone terkadang mengabaikan etika peliputan drone. Currently, drones have become a mandatory equipment in news coverage. Drones provide convenience and cost savings for the media to take bird eye pictures. With drones, mass media, especially television can enrich the visual aspect of their news. However, with all its advantages, the use of drones must still consider journalistic ethics such as privacy issues and permission to report among other things. This research is aimed to explore the perspective of journalists toward the journalism ethics on television news coverage using drone technology. This research used qualitative approach with phenomenology method.  This research involved four drone journalists from two television stations. Not many reporters can control a drone, each television station has four journalists who can do so. From the four drone reporters, the researchers took two certified and experienced drone reporters from each television station as participants. The result shows that not all drone reporters are aware about the ethics of drone usage on news coverage.  The demand to obtain good footage causes drone reporters to ignore journalism ethics on drone use.
Augmentation of the Life Time of Cyclo[18]carbon Accustomed with Carbon Nanotube and Zeolite
Authors: Rahaman Wahida , Bag Arijit
Published: December 2019

Recently synthesized cyclo[18]carbon which is characterized as polyyne D9h has a very short lifetime even at 5 K temperature. Its automerization is proposed through a transition state which is reported as a D18h symmetric cumulene. In the present article, an experimentally viable method for the enhancement of the lifetime of this compound is reported. The carbon nanotube is employed for this purpose. We also report that adopting numerous molecules of cyclo[18]carbon in the womb of a zeolite cage, wire-like countenance construction is feasible.
Rapid Quantification of Prion Proteins
Authors: Healey Matthew , Sivakumaran Muttuswamy , Platt Mark
Published: December 2019

Prion diseases are a group of fatal transmissible neurological conditions caused by the change in conformation of the normal intrinsic cellular prion protein (PrPC) in to the highly ordered insoluble amyloid state conformer (PrPSC). We present a rapid assay using Aptamers and Resistive Pulse Sensing, RPS, to extract and quantify proteins from complex sample matrices, demonstrate with the quantification of PrPc. We functionalise the surface of superparamagnetic beads, SPBs, with a DNA aptamer. First SPB’s termed P-Beads, are used to pre-concentrate the analyte from a large sample volume. The PrPc protein is then eluted from the P-Beads before aptamer modified sensing beads, S-Beads, are added. The velocity of the S-Beads through the nanopore reveals the concentration of the PrPc protein. The process is done in under an hour and allows the detection of picomol’s of protein. The technique could be easily adopted to the mutated version of the protein and integrated into clinical workflows for the screening of blood donations and transfusions.
KARAKTER DAN WARNA LOKAL CERPEN-CERPEN JAWA POS TAHUN 2000
Authors: Mashuri NFN
Published: December 2019

This research is trying to describe short stories in Jawa Pos written by East Java writers during 2000s. The purpose of the study is to explain local wisdom and characteristic among East Java people. Using the characterization and stylistic analysis, it turns out that the fictional characters in those East Java short stories are not merely single entity. The fact is actually correspondences with the multiethnics East Javanese socio-cultural values since it strongly influenc the East Java writers. However, black humour is the dominant factor as the style besides sarcastic, satire, and irony. Those writers are not only focusing on subculturally local wisdom and kampong values, but also interested in urban problems with its magic realism, sufism themes, and religiosity. Localities as the socio-cultural background are namely Arekan, Pesisir, Mataraman, and Madura. Therefore, we can conclude that short stories in Jawa Pos during 2000s have discourse transition in terms of millennium shift context, containing local issues which side-by-side with global matters as its themes
KRITIK ADJIDARMA DALAM EMPAT CERPEN: TENTANG GENDER DAN KELIYANAN
Authors: Nurfaidah Resti
Published: December 2019

Seno Gumira Ajidarma is well-known as a multitalented popular figure in Indonesia. He is an artist, a humanist, a writer, an academician, and others. His works are always in excellent quality. They need an incredible depth level of intrinsic aspect exploration. Previous studies have shown that criticism against government of the New Ordermassively appears on Ajidarma’s writting. However, the criticism is well-hidden behind his expertise in word processing and stories composing or other excellent quality works. This research is aimed into Ajidarma's social critique in the following four short stories: “Pelajaran Mengarang”, “Sepotong Senja untuk Pacarku”, “Telinga”, dan “Maria” which are focused on the concept of gender and Other's conflict. Based on the concepts of the Holmes gender and the Other of Callavaro, as well as several supporting references, it comes into the following outcomes: gender conflicts are connected to inferiority and superiority; the non-acceptancy of certain criteria and many causes make the inferior is victimizedwith the arbitrariness of the ruler in such forms: doctrine, alienation, discrimination, detention, torture, even murder; inferiority is resembling the present situation and conditions in this country
ANALISIS MAKROSTRUKTURAL DAN MIKROSTRUKTURAL PUISI KARYA ALI SYAMSUDDIN ARSI
Authors: Yulianto Agus
Published: December 2019

Tujuan penelitian ini adalah: 1) ingin mengungkapkan aspek sosial dan situasi yang terdapat dalam puisi yang dianalisis; dan 2) untuk mengetahui unsur-unsur grmatikal dan leksikal yang digunakan penyair dalam penciptaan puisinya tersebut. Adapun masalah dalam penelitian ini adalah: 1) bagaimana konteks sosial dan konteks situasi yang disajikan dalam puisi yang menjadi objek penelitian; 2) unsur-unsur gramatikal dan leksikal apa saja yang digunakan penyair dalam pembentukan puisinya. Kajian ini menggunakan metode deskriptif-analitik. Berdasarkan hasil analisis makrostruktural dapat diketahui bahwa konteks sosial dan konteks situasi yang ditampilkan dalam puisi adalah mengenai kerusakan alam di Kalimantan Selatan. Hasil analisis mikrostruktural menunjukkan bahwa puisi yang dianalisis memnfaatkan berbagai unsur gramatikal seperti referensi, ellipsis,dan konjungsi; dan juga memanfaatkan berbagai unsur leksikal seperti repetisi dan kolokasi
ANALISIS WACANA TALK SHOW PROGRAM MATA NAJWA “LELAKON ANTASARI AZHAR” DI METRO TV
Authors: Firdasari Irine Cyntia
Published: December 2019

Komunikasi massa di Indonesia berkembang pesat. Salah satu media massa yang paling diminati adalah televisi. Salah satu acara televisi yang paling diminati adalah program talk show. Tanggal 24 Agustus 2016 channel Youtube Metrotvnews memnyiarkan program Mata Najwa dengan mengangkat tema “Lelakon Antasari Azhar”. Tayangan ini dipicu karena terbitnya buku berjudul “Antasari Azhar: Saya dikorbankan” karangan Taufik Pram. Penelitian ini juga menggunakan metode analisis wacana dari Van Dijk yang memiliki tiga tahapan, namun peneliti hanya menggunakan satu tahapan karena fokus pada struktur teks dan bahasa. Penelitian ini menganalisis struktur teks atau bahasa dalam percakapan seputar talk show Mata Najwa “Lelakon Antsari Azhar” agar dapat diketahui ciri khas dari bahasa yang digunakan dalam program Mata Najwa. Dalam wacana “Lelakon Antasari Azhar” secara menyeluruh terdapat struktur makro, superstruktur serta struktur mikro dengan berbagai unsur - unsurnya. Wacana yang dapat disimpulkan dalam Mata Najwa “Lelakon Antasari Azhar” adalah penekanan kepada para penonton agar dapat mengetahui kebenaran di balik kasus yang menimpa Antasari Azhar.(Discourse Analysis Program "Lelakon Antasari Azhar"of Mata Najwa’s Talk Show on Metro TV)The development of mass communication in Indonesia is growing rapidly. One of the most popular public media is television. Moreover, one of the most popular television programs is talk show. At 24 August 2016, Mata Najwa has published talk show “Lelakon Antazari Azhar” on Metrotvnews Youtube channel. The show was triggered by the publication of a book entitled "Antasari Azhar: I was sacrificed" by Taufik Pram. This research uses discourse analysis by Van Dijk which has three stages, but the researcher only used one stage because it is focused on the text and language structure. This research analyzes the text or language structure in conversations surrounding Mata Najwa talk show "Lelakon Antasari Azhar" in order to know the characteristic of the language used. The results of the research "Lelakon Antasari Azhar" thoroughly there are macrostructure, superstructure, and microstructure with various elements. The discourse that can be concluded in Mata Najwa "Lelakon Antasari Azhar" is the emphasis on the audience in order to know the truth behind the case of Antasari Azhar
MANAGING DISRUPTIVE BEHAVIOUR OF PRIMARY STUDENTS IN THE EFL CONTEXT (Mengatasi Perilaku Mengganggu yang Dilakukan oleh Siswa Sekolah Dasar dalam Konteks Pembelajaran Bahasa Inggris)
Authors: Azizah Umu Arifatul , Rejeki Sri , Prihandoko Lastika Ary
Published: December 2019

Not all students are well motivated in the classroom activities. Some students often show disruptive behaviors that influence the teacher in conducting learning process. In particular case, there is special issue regarding behavioral problems in elementary school such as talking without permission and disturbing other friends while studying in class. Accordingly, this study aims at discerning behavior interruptions found in English teaching class. Moreover, it also describes the classification of students’ disruptive behaviors and explores teachers’ actions in order to overcome those behaviors. In this research, depth-interview with the English teacher, classroom observation and documentation were used to collect the data for two perceived classes and interactive model was used to analyze the data. Each class has been chosen based on specific characteristics for being observed. Though the study reported that there were several disruptive behaviors exhibited by primary school students, it could be classified as non-violence behavior since no one was injured by physical force. It seems possibly categorized as normal behavior by considering the students’ age and level in school. In the EFL context, students will be more focus and motivated if they are studying in comfortable class because students are required to master several skills of English. Comfortable class will lead them to comfortable learning. Henceforth, it was suggested that teacher should have adequate knowledge of the students’ psychology based on their age in order to give the proper strategies to control disruptive behaviors in the classroom.
Essential functions of Runx/Cbfβ in gut conventional dendritic cells for priming Rorγt+ T cells
Authors: Tenno Mari , Wong Alicia Yoke Wei , Ikegaya Mika , Miyauchi Eiji , Seo Wooseok , See Peter , Kato Tamotsu , Taida Takashi , Oishi-Ohno Michiko , Ohno Hiroshi , Yoshida Hideyuki , Ginhoux Florent , Taniuchi Ichiro
Published: December 2019

Acquired immune responses are initiated by activation of CD4+ helper T (Th) cells via recognition of antigens presented by conventional dendritic cells (cDCs). DCs instruct Th-cell polarization program into specific effector Th subset, which will dictate the type of immune responses. Hence, it is important to unravel how differentiation and/or activation of DC are linked with Th-cell–intrinsic mechanism that directs differentiation toward a specific effector Th subset. Here, we show that loss of Runx/Cbfβ transcription factors complexes during DC development leads to loss of CD103+CD11b+ cDC2s and alters characteristics of CD103−CD11b+ cDCs in the intestine, which was accompanied with impaired differentiation of Rorγt+ Th17 cells and type 3 Rorγt+ regulatory T cells. We also show that a Runx-binding enhancer in the Rorc gene is essential for T cells to integrate cDC-derived signals to induce Rorγt expression. These findings reveal that Runx/Cbfβ complexes play crucial and complementary roles in cDCs and Th cells to shape converging type 3 immune responses.
A comprehensive resource for retrieving, visualizing, and integrating functional genomics data
Authors: Blum Matthias , Cholley Pierre-Etienne , Malysheva Valeriya , Nicaise Samuel , Moehlin Julien , Gronemeyer Hinrich , Mendoza-Parra Marco Antonio
Published: December 2019

The enormous amount of freely accessible functional genomics data is an invaluable resource for interrogating the biological function of multiple DNA-interacting players and chromatin modifications by large-scale comparative analyses. However, in practice, interrogating large collections of public data requires major efforts for (i) reprocessing available raw reads, (ii) incorporating quality assessments to exclude artefactual and low-quality data, and (iii) processing data by using high-performance computation. Here, we present qcGenomics, a user-friendly online resource for ultrafast retrieval, visualization, and comparative analysis of tens of thousands of genomics datasets to gain new functional insight from global or focused multidimensional data integration.
MERLIN: a novel BRET-based proximity biosensor for studying mitochondria–ER contact sites
Authors: Hertlein Vanessa , Flores-Romero Hector , Das Kushal K , Fischer Sebastian , Heunemann Michael , Calleja-Felipe Maria , Knafo Shira , Hipp Katharina , Harter Klaus , Fitzgerald Julia C , García-Sáez Ana J
Published: December 2019

The contacts between the ER and mitochondria play a key role in cellular functions such as the exchange of lipids and calcium between both organelles, as well as in apoptosis and autophagy signaling. The molecular architecture and spatiotemporal regulation of these distinct contact regions remain obscure and there is a need for new tools that enable tackling these questions. Here, we present a new bioluminescence resonance energy transfer–based biosensor for the quantitative analysis of distances between the ER and mitochondria that we call MERLIN (Mitochondria–ER Length Indicator Nanosensor). The main advantages of MERLIN compared with available alternatives are that it does not rely on the formation of artificial physical links between the two organelles, which could lead to artifacts, and that it allows to study contact site reversibility and dynamics. We show the applicability of MERLIN by characterizing the role of the mitochondrial dynamics machinery on the contacts of this organelle with the ER.
O humor como problema de pesquisa em Estudos da Tradução
Authors: Luiz Tiago Marques , Martínez Sierra Juan José , Zabalbeascoa Terran Patrick
Published: December 2019

Este artigo é uma visão geral dos estudos de tradução aplicados ao caso do humor, divididos em quatro partes, além de uma extensa bibliografia. A primeira parte repassa a tradução do humor como objeto relevante de pesquisa e por que merece maior atenção acadêmica. A tradução de humor não deve ser tratada ou encarada como um corpo estranho nos estudos de tradução. A segunda parte é uma visão geral das principais contribuições para o campo, da Espanha e de outros lugares, abrangendo um número considerável de autores e teorias. A terceira parte se concentra em áreas de interesse promissoras para pesquisadores e ilustra como a tradução audiovisual é um bom exemplo de dinamismo dentro do campo, conectando tudo isso à rica variedade de formatos e à importância da tecnologia. A parte quatro esboça a paisagem de métodos de pesquisa e estruturas teóricas para indicar possíveis armadilhas envolvidas quando as metodologias e os quadros teóricos não são organizados de forma clara e coerente, dadas as complexidades do estudo da tradução do humor.
Cloud-Based Computing: Providing an Advantage to a Small New Zealand Wine Business
Authors: Forbes Sharon L. , Alsulaiman Khalid
Published: December 2019

Oliver and Charlotte Martin (names disguised at their request) were both employed full time and leading very busy lives when they purchased their small, wine-celebration business located in New Zealand. The Martins desired to play pivotal managerial roles in their new wine business while remaining in their current jobs, but soon realized that they had become over-committed and needed to outsource the accounting of their wine business to a seasoned professional. The Martins wondered whether investing in new information technology, specifically cloud-based accounting and customer relationship management (CRM) solutions, could help them become more efficient and effective as their winery operations grew.

This case examines the risks and rewards of implementing cloud-based software programs. It also illustrates the linkages between the fields of marketing and management accounting, as the software programs highlighted in the case study have the ability to be integrated with each other.
Medidas de prevención de la transmisión de la influenza en trabajadores agrícolas desde un análisis de su patogénesis
Authors: Saldaña Diego Alejandro , Majey Andrea del Pilar
Published: December 2019

El virus de la influenza se ha constituido como un agente infeccioso de gran importancia en la población vulnerable siendo una de las principales causas de morbilidad en el mundo. En el caso concreto de los trabajadores del sector agrícola, el carácter de enfermedad zoonótica permite que el virus pueda presentar cambios en su estructura, lo que puede llevar a un aumento de la capacidad infectiva del germen. Este artículo pretende describir las medidas que se pueden adoptar en la prevención de la transmisión del virus, visto desde la patogénesis de la misma y con base en las implicaciones que tiene en la salud pública. Teniendo en cuenta que el viraje genético de la enfermedad abarca no sólo la salud de los trabajadores, sino también la salud de la población en general.
A typological shift in the phonological history of German from the perspective of licensing scales
Authors: Fortuna Marcin
Published: December 2019

The paper argues that the typological shift of German from a syllable language to a word language (Szczepaniak 2007) can be accounted for through reference to a change at the level of the nuclei and their licensing abilities (Cyran 2003, 2010). Old High German used full nuclei in all positions of the word. In the late Old High German period, unstressed vowel reduction took place and entailed a domino effect of further changes. Reduced vowels were granted more licensing potential, and empty nuclei were strengthened too. This parametric shift is assumed to lie at the heart of the whole typological shift. There is no need to state that Old High German “profiled” the syllable, while Modern High German “profiles” the word, since most of the associated phenomena can be explained with more basic mechanisms.
The importance of formal grammar skills: Reflections on Polish students learning Norwegian
Authors: Haugan Jens
Published: December 2019

Norwegian and Scandinavian languages in general have grown quite popular among Polish students in recent years and more and more Polish universities are trying to offer Bachelor’s and even Master’s programmes in a Scandinavian language.

Based on experience as a teacher of a Norwegian grammar course at the University of Szczecin and as a teacher of grammar at the Inland Norway University of Applied Sciences which in 2016/2017 hosted around twenty Erasmus+ students from Szczecin, some of the challenges for Polish students of academic Norwegian will be reflected upon, as well as some of the challenges for a teacher of Norwegian who has very little knowledge of Polish. The main purpose of this paper will be to argue for the importance of grammar skills in language education and especially in language teacher education. This study is a contribution to the Educational Role of Language network.
Defining the dystopian chronotope: Space, time and genre in George Orwell’s 'Nineteen Eighty-Four'
Authors: Terentowicz-Fotyga Urszula
Published: December 2019

The paper examines George Orwell’s Nineteen Eighty-Four as a canonical example of the dystopian novel in an attempt to define the principal features of the dystopian chronotope. Following Mikhail Bakhtin, it treats the chronotope as the structural pivot of the narrative, which integrates and determines other aspects of the text. Dystopia, the paper argues, is a particularly appropriate genre to consider the structural role of the chronotope for two reasons. Firstly, due to utopianism’s special relation with space and secondly, due to the structural importance of world-building in the expression of dystopia’s philosophical, political and social ideas. The paper identifies the principal features of dystopian spatiality, among which crucial are the oppositions between the individual and the state, the mind and the body, the high and the low, the central and the peripheral, the past and the present, the city and the natural world, false and true signs.
From solidarity with the people to solidarity with the ‘company’: State capture and Karen Jayes’ dystopian novel ,For the Mercy of Water' (2012)
Authors: Mengel Ewald
Published: December 2019

For the Mercy of Water sheds light on an uncanny conjunction between the rape of women, the rape of a country and the rape of the truth. It relates a story about the vulnerability and resilience of women in a phallogocentric world. It deals with the phenomenon of ‘state capture’, the exploitation and abuse of state institutions and resources for the sake of private profit. Last but not least, it examines the relation of journalism and novel writing and flies the flag of truth-telling as a form of bearing witness and ‘remembering’ in a post-factual and increasingly totalitarian environment.
Questions about solidarity in the dystopian world (inspired by Dmytro Ternovyi’s 'High Resolution')
Authors: Ursulenko Anna
Published: December 2019

The article discusses the means of creating images and argumentation lines used to achieve a multidimensional representation of the concept of solidarity in the 2012 drama High Resolution by Ukrainian playwright Dmytro Ternovyi. The story of inhabitants of a certain Ukrainian city and their experiences during anti-regime protests coinciding with the hunt for immigrants organized by the authorities is interspersed with fantastic and grotesque scenes featuring animate objects, which allowed the author to create a range of social worlds haunted by traumas and fears. By definition, a dystopian reality is a space where social relationships are disturbed, which may cause the society to atomize, but it can also consolidate it. Ternovyi shows both options, indicating that it is possible to have an ambivalent point of view on solidarity. He creates alternative variants of development of such situations. The analysis of those visions shows that it is possible to perceive the discussed drama as a specific study of solidarity – an anatomy of its triumphs and failures. Furthermore, setting the drama in the context of the recent events in Ukraine made it possible to correlate solidarity and collective identity and show current trends in thinking about the Ukrainian identity.
Mere solidarity is not enough: Exploring dystopian reality in Edward Bond’s 'The Tin Can People'
Authors: Varal Seçil
Published: December 2019

Solidarity is an indispensable part of the utopian and dystopian world since people gather around a common cause either to create an ideal community or to get rid of a difficult situation. Unlike utopia, in which solidarity mostly comes out voluntarily, in dystopia, it grows up compulsorily triggered by emotions such as anxiety, distrust, paranoia, and fear primarily due to a totalitarian regime or the effects of a nuclear war. However, in The Tin Can People (1984), British playwright Edward Bond propounds a new perspective to postapocalyptic dystopia by portraying a group of people who create a utopian community, a heaven in the aftermath of a nuclear holocaust, as a result of living in solidarity. This article aims to trace how dystopian world reveals the bitter ‘reality’ against this illusionary heaven with the arrival of a stranger and dissolves the community despite the solidarity that the survivors have been preserving for years to show that mere solidarity is not enough to save a community.
The strategies of seeing differently in Kathleen Jamie’s travel writing: 'Findings' and 'Sightlines'
Authors: Dziok-Łazarecka Anna
Published: December 2019

This article looks at the narrative techniques employed in two collections of creative non-fiction essays by the Scottish writer and poet, Kathleen Jamie. In Findings (2005) and Sightlines (2012) the narrator uses the theme of travel as a platform for expressing the liminality of natural and cultural zones. At the same time, the concept of motion and the boundless travel experience are often turned into their diminutive forms. In order to transgress the dual notions of outside/inside, human/nonhuman and the visible/unseen, Jamie employs a number of visual strategies. She introduces experimental methods of observation to free perception from the constraints of the dogmatic predictions which emerge from the automatization of sight. Jamie exposes our own illusions of what “natural” is or where exactly “nature” resides, prompting us to rethink our own position in the system. In this she often demonstrates the ethical environmental agenda of contemporary Scottish writers and exposes the intrusion of globalism into parochial zones.
The strange case of Francis Dolarhyde and the Dragon: Alternating narrative points of view and the source of knowledge in Thomas Harris’ 'Red Dragon'
Authors: Stiepanow Justyna
Published: December 2019

This paper investigates the narrative voice employed by Thomas Harris in Red Dragon as a source of knowledge about the fictional universe, more particularly about the main villain, Francis Dolarhyde. Confronting important epistemological notions (knowledge, justification and their sources) with literary theoretical concepts (narrative voice and points of view), I analyse alternating modes of representation. Harris’ narrator shifts between three modes: the quasi-perceptual one – sense-based, rich in descriptive elements; the quasi-introspective narration carried out from a close subjective angle, using free indirect speech or stream of consciousness; and the testimonial mode – telling (rather than showing) the story through exposition resting on the principle of cause and effect. Employing a vast array of inter-textual pragmatics, the narrative remains ambiguous. In consequence, any proposition about Dolarhyde can be empirically and rationally challenged and all propositional knowledge regarding the character is merely fragmentary.
CITY REVIEW: KYIV BY PAGES OF THE MEMORIAL HERITAGE OF SCIENTISTS (20–30s, 20TH CENTURY)
Authors: Hedo Anna , Kaluzhyna Anastasia
Published: December 2019

In scientific research on the basis of analytical and synthetic criticism of the memoirs of Ukrainian scientists S. Yefremov, M. Hrushevskyi, K. Kharlampovych, A. Krymskyi, N. Polonska-Vasylenko is made an attempt to analyze the daily life of the scientific elite in the conditions of the establishment of Soviet power and to trace the influence of cultural transformations and the scientific atmosphere of Kyiv of 20–30s of the 20th century on the socio-legal status of scientists and their further destiny.In the brutal conditions of the Soviet system writing letters and memoirs, it was the only way of expressing a person of intellectual work that could not accept the loss of a sovereign right on free labor.Soviet propaganda had created an attractive image of Kyiv as an All-Union scientific center, attracting more and more attention to VUAN as the only institution capable of meeting the intellectual requirements of scholars. Dozens of emigre scholars had believed in the demagogy of the Bolsheviks, made a fateful step in their lives back to their homeland, because crossed the Soviet border was difficult to remain a rebellious person with preserved principles and views on morality, without losing their own lives. However, in such conditions there were people who, despite all the obstacles, tried to serve the Ukrainian people as long as possible in the bosom of science, to preserve its identity and historical heritage at the cost of their own lives. With the establishment of Soviet power, the Bolsheviks tried to "re-educate" and conquer the scientific elite as the main generator of democratic and national ideas for a totalitarian system. On the way to this goal, the Soviet authorities used any methods, starting with material domestic pressure, and ending with open repressions against the scientific elite of Kyiv, in order to destroying its authority as a sociocultural phenomenon. The result of this policy was a sharp decline in living standards and productivity of Ukrainian scientists, numerous repressions against so-called "bourgeois nationalists" as a symbol of the impoverishment of the Ukrainian idea. Thus, the transformation of the cultural and scientific atmosphere of Kyiv under the influence of the Soviet ideology turned it from the All-Union scientific center into the city of thousands of ruined fates.
COVARIANCE BASED-SEM ON RELATIONSHIP BETWEEN DIGITAL LITERACY, USE OF E-RESOURCES, AND READING CULTURE OF STUDENTS
Authors: Marliana Reny Rian , Nurhayati Leni
Published: December 2019

In this paper, a relationship model among latent variables using Covariance Based-Structural Equation Modeling (CB-SEM) is studied. The latent variables are digital literacy, use of e-resources and reading culture of students. The goal of the study is to build a simultaneously model between those three variables, determine the influence of digital literacy on the use of e-resources and reading culture of students, and the influence of the use of e-resources on reading culture of students. The parameters of the model are estimated by the Maximum Likelihood method. This study took data from 256 questionnaires of students at STMIK Sumedang. Results showed that digital literacy significantly influences the use of e-resources and the reading culture of students. In contrast, there are no significant influences on the use of e-resources on the reading culture of the student.
Analisis Ramuan Jamu Antihipertensi di Rumah Riset Jamu Hortus Medicus Tawangmangu Periode Januari-Juni 2017
Authors: Ardiyanto Danang , Friska Dewi Tyas
Published: December 2019

Salah satu penyakit tidak menular yang memiliki prevalensi tinggi di dunia adalah hipertensi. Selain menggunakan pengobatan konvensional, penatalaksanaan hipertensi dapat ditangani dengan jamu. Penelitian  bertujuan memeroleh gambaran penggunaan, persentase keberhasilan terapi dan jenis kelamin serta frekuensi terapi, dengan keberhasilan terapi ramuan jamu antihipertensi di Rumah Riset Jamu (RRJ) Hortus Medicus. Desain penelitian menggunakan potong lintang dengan rancangan observasional deskriptif. Observasi dilakukan pada data sekunder berupa rekam medik. Ramuan antihipertensi yang digunakan di RRJ periode Januari-Juni 2017 adalah ramuan I terdiri dari tanaman obat Apium graveolens‚ Centella asiatica‚ Orthosiphon stamineus dan Imperata cylindrica dengan 70 resep (70%). Ramuan II terdiri dari Apium graveolens‚ Centella asiatica‚ Orthosiphon stamineus‚ dan Imperata cylindrica dan Sonchus arvensis dengan 20 resep (20%). Ramuan III terdiri dari Apium graveolens‚ Centella asiatica dan Orthosiphon stamineus dengan 10 resep (10%). Persentase keberhasilan terapi  ramuan jamu 1‚ 2‚ dan 3 berturut-turut adalah 80%‚ 60%‚ dan 50%. Faktor-faktor yang mempengaruhi keberhasilan terapi adalah jenis kelamin dan frekuensi terapi. Jenis kelamin tidak memiliki korelasi yang signifikan dengan keberhasilan terapi hipertensi dengan nilai p=0‚705 (p>0‚05)‚ dengan nilai Odds Ratio (OR) sebesar 1‚151.  Faktor frekuensi terapi juga tidak memiliki korelasi yang signifikan dengan keberhasilan terapi hipertensi dengan nilai p=0‚420 (p>0‚05)‚ dengan nilai Odds Ratio (OR) sebesar 3‚421.
O ensino da administração pública no Brasil: uma revisão sistemática
Authors: Amorim Denia Aparecida de , Santos Robson Rodrigues dos , Pereira Rubens José
Published: December 2019

O tema Administração Pública tem sido uma expressão adotada por docentes, pesquisadores, discentes, egressos, profissionais e dirigentes de cursos de graduação e pós-graduação em áreas ligadas a gestão dos entes públicos. O processo de redemocratização brasileira alterou a natureza das relações entre a sociedade e o Estado, o que ocasionou transformações políticas, organizacionais e gerenciais. A Constituição Federal de 1988 incluiu direitos políticos e sociais como saúde, educação, assistência social e amparo à infância e à adolescência, ampliando as premissas de atuação governamental e a demanda por serviços públicos, consequentemente, a exigência de eficiência por parte da Administração Pública e de seus servidores. Assim, o objetivo geral dessa pesquisa foi mapear as produções acadêmicas acerca do ensino e/ou graduação em administração pública no Brasil nos últimos dez anos, bem como identificar os temas abordados nesses estudos. A pesquisa foi realizada pelo método qualitativo de revisão sistemática. Os principais resultados apresentam o aumento crescente da oferta de cursos superiores em AP, além de crescimento no volume de publicações científicas acerca da temática.
Evasão na educação a distância: uma revisão sistemática
Authors: Vellozo Sarah Rachel Gonczarowska , Canella Raquel dos Santos , Dias Aurimar Andrade , Leal Geraldo Sadoyama
Published: December 2019

O objetivo deste trabalho é mapear os estudos efetuados acerca da evasão na educação a distância, através de uma revisão sistemática, por meio de uma busca por artigos completos indexados, realizada nas bases de dados CAPES e SCiELO, com o uso dos descritores: “evasão na EaD”, incluindo estudos publicados no período entre os anos de 2013 á 2018. Foram encontrados 11 artigos por meio de critérios de seleção pré-estabelecidos, os quais subsidiaram a elaboração de uma sinopse de estudos, contento título, ano, base de dados, instrumentos, objetivos e principais conclusões. Com base na análise dos artigos selecionados conclui-se a necessidade de uma mudança na forma e na estrutura do sistema de ensino a distância, abrangendo outros elementos, visando uma maior sintonia entre os envolvidos no processo de ensino-aprendizagem, bem como a necessidade por melhorias na elaboração do material didático utilizado e maior uso das tecnologias de informação e comunicação (TIC’s), para promover uma aprendizagem mais autônoma por parte dos alunos. Por fim, este trabalho nos permite afirmar que ainda se fazem necessárias pesquisas futuras que possibilitem alcançar uma maior compreensão sobre os motivos que levam os alunos à evasão na educação a distância.