bluuebunny/crossref_metadata_2025 huggingface dataset:
Spatial and temporal dynamics of the prevalence of resistance genes and gastrointestinal pathogens in stool samples of German deployment returnees
Authors: Navabi Vanessa , Wiemer Dorothea Franziska , Halfter Matthias , Müseler Ulrich , Dupke Susann , Petrov-Salzwedel Anja , Schotte Ulrich , Frickmann Hagen
Published: October 2024

Background

The exploratory study assessed trends in the abundance of CTX-M-type extended spectrum beta-lactamase (ESBL) and vancomycin-resistance genes vanA and vanB in the stool samples of German soldiers and police officers returning from predominantly tropical deployments next to the common diarrheagenic Escherichia (E.) coli pathovars enteropathogenic Escherichia coli (EPEC), enterotoxigenic E. coli (ETEC) and enteroaggregative E. coli (EAEC)) as well as rarely imported Vibrio spp. between 2006 and 2024.

Methods

Surveillance was performed applying real-time polymerase chain reaction and results were stratified by World Health Organization region of deployment as well as by deployment period. For the latter, the study interval was divided into three pre-COVID-19-pandemic periods, the COVID-19-pandemic period and the post-COVID-19-pandemic period. Averaged prevalences were used as references.

Results

In stool samples of 1817 deployed German soldiers and 117 police officers, averaged prevalences were 47.9% and 24.8% for the ESBL-type beta-lactamase blaCTX-M, 30.2% and 14.5% for vanB, 9.0% and 17.9% for EPEC, 3.4% and 12.8% for ETEC, 4.0% and 3.4% for EAEC as well as 2.0% and 3.4% for Vibrio spp., respectively. While resistance genes peaked during early deployments, maximum prevalences for enteropathogens were seen later.

Conclusions

The assessment suggested time- and region-dependence of the assessed parameters.
A recent update on the antibacterial effects of distinct bioactive molecules derived from the Cannabis plant
Authors: Werner Mathis , Bereswill Stefan , Heimesaat Markus M.
Published: October 2024

The number of human infections with multidrug-resistant (MDR) bacteria is increasing worldwide and constitutes a serious threat to human health. Given the lack of novel antibiotic compounds worsening this dilemma, alternative antibiotic-independent treatment and prevention strategies of infectious diseases applying natural compounds appear highly appreciable. Given the long-known health-beneficial and disease-alleviating properties of Cannabis, we performed a literature search summarizing current knowledge regarding the antibacterial effects of extracts from different parts of the Cannabis sativa plant and of defined Cannabis-derived molecules and their potential mode of action. The included studies revealed that various extracts and essential oils of C. sativa as well as major cannabinoids exerted potent activities against a broad spectrum of Gram-positive bacteria and against some Gram-negative bacterial species including MDR strains. Particularly the disruption of the bacterial cytoplasmic membrane by some cannabinoids resulted in potent antibacterial effects against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus. Furthermore, defined cannabinoids inhibited the formation of and eradicated existing bacterial biofilms. In conclusion, given their antibacterial properties distinct Cannabis-derived molecules expand the repertoire of antibiotics-independent treatment options in the combat of bacterial infectious diseases which should be further addressed in future studies including clinical trials.
A jól és a dedifferenciált liposarcomák morfológiai és immunhisztokémiai jellegzetességei
Authors: Akbarzadeh Mersad , Pancsa Tamás , Sejben Anita
Published: October 2024

Bevezetés: A liposarcomák morfológiailag változatos csoportot
alkotnak a mesenchymalis malignitások között. A lágyrész-daganatok
diagnosztikája során mindig fel kell merülnie a jól differenciált és a
dedifferenciált liposarcoma lehetőségének. E daganatok eddigi legmegbízhatóbb
immunhisztokémiai markere az MDM2 volt, a liposarcomák azonban más markerekkel
is sokféle pozitivitást mutathatnak. Módszer: Tanulmányunkban a
Szegedi Tudományegyetemen ismételten áttekintettük a 2017 és 2022 között
előfordult, jól és dedifferenciált liposarcomás eseteket, és szükség esetén
további immunhisztokémiai vizsgálatokat végeztünk, beleértve az MDM2-, CDK4-,
p16- és STAT6-vizsgálatot. Eredmények: Kohorszunkban 7 esetben
fordult elő jól differenciált, 11 esetben pedig dedifferenciált liposarcoma.
Minden morfológiai mintázatot regisztráltunk és lefényképeztünk. Az esetek több
mint felében a tumor a retroperitoneumban helyezkedett el (n = 11), és 8
betegnél T4-es stádiumban jelentkezett. Az MDM2 minden esetben fokálisan vagy
diffúzan pozitív volt (n = 18), míg a CDK4 és a p16 szinte minden esetben
diffúzan pozitívnak bizonyult (n = 17). A morfológiai változatosság ellenére az
összes dedifferenciált liposarcoma (n = 11) pozitív volt MDM2-, CDK4- és
p16-reakcióval is. A STAT6 3 dedifferenciált liposarcomás esetben mutatott
multifokális nukleáris pozitivitást. Következtetés: A
liposarcoma diagnózisának felállításához MDM2, CDK4 és p16 immunhisztokémiai
reakciókat, valamint MDM2 fluoreszcens in situ hibridizációt
szükséges végezni. Dedifferenciált liposarcomás eseteink jelentős kisebbsége
mutatott multifokális pozitivitást a STAT6-tal, ezért a solitaer fibrosus
tumorokból származó kis mintáknál az MDM2-reakció elvégzése ajánlott a
liposarcoma lehetőségének kizárására. Tanulmányunk az első, amely a liposarcomák
valamennyi jól ismert morfológiai mintázatát tartalmazza. Orv Hetil. 2024;
165(43): 1700–1706.
Fragkiska Megaloudi: Plants and Diet in Greece from Neolithic to Classic Periods: the archaeobotanical remains
Authors: Dalby Andrew
Published: October 2024

Fragkiska Megaloudi: Plants and Diet in Greece from Neolithic to Classic Periods: the archaeobotanical remains: Archaeopress: ISBN 1841719498: 95pp.: £28.
Mary Chafin: Original Country Recipes
Authors: D. J.M.
Published: October 2024

Mary Chafin: Original Country Recipes: Macmillan, London, 1979: 84 pp., £2.95.
Robert Forster and Orest Ranum (ed.): Food and Drink in History (being selected essays from Annales-Economies, Socihes, Civilisations)
Authors: Davidson Alan E
Published: October 2024

Robert Forster and Orest Ranum (ed.): Food and Drink in History (being selected essays from Annales-Economies, Socihes, Civilisations): The John Hopkins University Press, 1979: 173 pages, U.S. price $4.95.
Cartographies for an inclusive Open Science
Authors: Beigel Fernanda
Published: October 2024

The Call for the STI Conference held in September 2024, in Berlin, argues that there is a variety of processes of openness among different communities and stakeholders which pose questions about the interaction of openness and closedness. It stimulates the participants to ask how much closedness is embedded in openness and vice versa and how to measure these intertwined phenomena. This keynote has been framed in these basic concerns and intends to advance towards the intersection with inclusiveness, considering that openness is necessary but not sufficient to achieve a more equitable and effective scholarly communication globally. In the convergence of field approach and structural heterogeneity, we build a conceptual framework to assess the combinations observed in the space of open science, and the stakeholders that represent forces towards inclusiveness or exclusiveness.
Exploring the main indicators of inclusive openness, 7 cartographies are proposed for a global mapping and the discussion of the main issues at stake towards a just transition to open science: 1) a comparison between the distribution by country of repositories of published output and primary data repositories, 2) a mapping of the Current Information systems (CRIS) and their different developments at the national and institutional level, 3) a cartography of persistent identifiers of digital resources comparing DOI and ARK, 4) a cartography of persistent identifiers for  active researchers (ORCID) by country and its weak representation of the national research communities, 5) a comparison of the coverage of identifiers of research organizations (ROR) with a national database of organizations, 6) a cartography of indexed journals with no-fee for publishing or reading and 7) a mapping of multilingualism in scholarly publishing, by platform. Finally, some study cases are discussed to show examples of the limited inclusiveness of the current state of open infrastructures and publishing platforms.
İlkokul Dördüncü Sınıf Öğrencilerinin Okuduğunu Anlama Performanslarının Farklı Tekniklerle Karşılaştırılması
Authors: Kocaarslan Mustafa , Çelik Zehra , Yıldırım Kübra Nur
Published: October 2024

Bu araştırmada dördüncü sınıf öğrencilerinin cümle doğrulama testi, boşluk tamamlama testi, yeniden anlatma ve açık-uçlu sorular ile ölçülen okuduğunu anlama puanları arasındaki ilişkiler incelenmiştir. Bununla birlikte öğrencilerin farklı tekniklerle ölçülen okuduğunu anlama puanlarının cinsiyet, okuma ortamı tercihi, evde kitaplığa sahip olma ve okunan kitap sayısına göre farklılaşıp farklılaşmadığı araştırılmıştır. Araştırma sonucunda genel olarak bütün okuduğunu anlama ölçümleri arasında düşük düzeyden yüksek düzeye kadar pozitif ve anlamlı ilişkiler tespit edilmiştir. Kızlar erkeklere göre tüm okuduğunu anlama ölçümlerinde daha üstün performans göstermiştir. Ayrıca okuma ortamı açısından bütün testlerde basılı okumayı tercih edenler lehine anlamlı farklılık bulunmuştur. Evinde kitaplık bulunan öğrencilerin olmayanlara göre yalnızca yeniden anlatma puanları anlamlı derecede yüksek bulunmuştur. Aylık daha fazla kitap okuyan öğrenciler yalnızca cümle doğrulama testinde yüksek performans elde etmiştir.
Gender Differences in Cognitive Function of Schizophrenia Patients
Authors: Park Kyounghwan , Choi Mal-Rey , Shin Ye-Eun , Han Myeong-Il
Published: October 2024

Objectives: Cognitive impairment is a fundamental symptom of schizophrenia, an often-overlooked aspect of the disorder that has gained recent attention due to its direct relation with functional outcomes and implications for medical and social costs. This study aims to investigate gender differences in cognitive function among patients with schizophrenia using Korean Wechsler Adult Intelligence Scale-IV (K-WAIS-IV).Methods: Data were collected from inpatients and outpatients treated at Presbyterian Medical Center between January 1, 2019, and December 31, 2023. Patients diagnosed with schizophrenia underwent evaluation with the K-WAIS-IV. Multivariate analysis of variance was utilized to assess cognitive differences between men and women participants, while correlation analysis was performed to explore associations between cognitive performance and clinical data.Results: Among 101 candidates, 26 male and 26 female patients were selected for analysis of their K-WAIS-IV scores and clinical data. The results revealed no statistically significant differences in cognitive function between male and female patients concerning Full-Scale Intelligence Quotient (FSIQ) and the four index scores: Verbal Comprehension Index (VCI), Perceptual Reasoning Index (PRI), Working Memory Index (WMI), and Processing Speed Index (PSI). A trend indicating preserved verbal intelligence relative to performance intelligence was observed. Additionally, the VCI exhibited a positive correlation with age, while both FSIQ and PSI demonstrated positive correlations with years of education.Conclusion: The findings of this investigation suggest that there are no significant differences in cognitive function between male and female patients with schizophrenia via K-WAIS-IV. Given the heterogeneity of the sample and potential limitations of the neurocognitive assessments employed, further research utilizing more targeted methodologies and sensitive measures is warranted.
FORMATION OF MEDICAL TOURISM CLUSTERS IN THE TERRITORIAL STRUCTURE OF THE HEALTHCARE SECTOR: ISSUES OF METHODOLOGY AND TECHNIQUES
Authors:   Institute of Earth Sciences, St. Petersburg University, Grudtsyn Nikolai A. , Chistobaev Anatoly I. ,   Institute of Earth Sciences, St. Petersburg University
Published: October 2024

The article deals with the theoretical, methodological, and procedural aspects of the cluster approach to the study ofmedical tourism: the choice of a place where a cluster can be created; search for partners in the formation and functioning of the cluster; development of a marketing strategy and qualified management. The paper highlights the advantages of clustering in medical tourism: medical tourism clusters ensure a synergistic effect in the provision of medical services, increase the region’s attractiveness for tourists, and ensure growing income of medical and health institutions. The shortcomings of the formation of medical tourism clusters include the risks of monopolization of the medical services market, of restrictions on competition, and of disproportions in the healthcare development. The negative impact of medical tourism clusters on the environment can be minimized – the main task in ensuring environmental safety is the disposal of medical waste and preventing it from entering water and air basins. The paper provides recommendations for potential patients to choose a cluster that would correspond to their request for medical care. It is shown that for a successful development of medical tourism, when creating clusters it is necessary to take into account potential challenges and eliminate real risks. A formula for calculating the medical tourism cluster index is proposed. It is noted that the formation of medical tourism clusters is a complex and multifaceted process that requires coordinated joint efforts and actions from all its participants. With a successful implementation of projects aimed at creating such high-tech clusters in countries and regions where medical tourism is developed, an economic effect can be obtained with minimal environmental impact. The paper also notes the need for the formation of centralized statistics on medical tourism.
ON THE DESIGN OF A SCHEME OF PROTECTED NATURAL AREAS IN THE KRASNODAR REGION. A GEOINFORMATION ASPECT
Authors:   Kuban State University, Pogorelov Anatoly V. , Kiselev Evgeny N. ,   Kuban State University, Makhonin Vasily L. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops
Published: October 2024

The paper presents the results of designing a scheme of protected natural areas in Krasnodar Territory (region) using satellite images and geoinformation mapping. The proposed substantiation of the location of protected areas is based on the biogeocenotic approach. The geobotanical factor of their location was taken into account through the accepted florogenetic zoning of the territory. The geoinformation aspect in the study was the key one and included a set of sequential actions: determining the location of promising protected areas based on data from the PROBA-V satellite system with a spatial resolution of 100 m (zonal design scale),analyzing the representativeness of vegetation cover types and unvegetated lands on sites of proposed protected areas (local scale),mapping and cartometric calculations, creation of a GIS of protected areas of the region. The design process was preceded by an analysis of the existing network of protected areas of Krasnodar Territory comprising 424 objects of various significance and categories with a total area of 958.7 thousand hectares, or 12.7% of the region’s territory. The scheme includes 29 territories with a total area of 24.6 thousand hectares. In each of the 10 florogenetic areas on the territory of the region, the organization of protected areas is proposed in accordance with the biogeocenotic approach. At the zonal level, the largest number of reserves (14) are designed in florogenetic areas in the flat part of the region in order to preserve the discovered fragments of primary natural complexes – grassforb and shrub steppes, ravine oak forests, and floodplain forests. At the local level, in determining the contours and sizes of the protected areas, the priority was the representativeness of vegetation cover types, established from satellite images.
Más de 100 adiciones a la flora de Sinaloa: la contribución de nuevas exploraciones y la ciencia ciudadana a la investigación botánica
Authors: Pío-León Juan Fernando , González-Gallegos Jesús Guadalupe , Castro-Castro Arturo , González-Bernal Marco Antonio , Rojas-Aguilar Edmi Itzel , Martínez-Flores Mixael Erasmo , Payán-Cázares Efraín , Gámez-Duarte Edgar Alberto
Published: October 2024

Antecedentes: Sinaloa es uno de los estados con menor número de colectas botánicas en México, pero con mayor número de observaciones en la plataforma iNaturalist/iNaturalistMX. En 2021 se publicó el listado florístico del estado, pero desde entonces se han realizado nuevas exploraciones y descubrimientos.
Preguntas: ¿Cuántas y cuáles especies de plantas vasculares deben añadirse al listado de Sinaloa? ¿Qué fuentes de información las sustentan?
Especies de estudio: Plantas vasculares.
Sitio y años de estudio: Sinaloa, México (2021-2024).
Métodos: Se revisó literatura, herbarios, repositorios digitales, iNaturalistMX y se ejecutaron exploraciones botánicas. Se realizaron análisis de riqueza para las especies añadidas mediante exploraciones recientes y se compararon con las bases de datos de colecciones y iNaturalistMX.
Resultados: Se añadieron 130 especies a la flora de Sinaloa, incluyendo tres familias (Podocarpaceae, Simaroubaceae y Symplocaceae) y 18 géneros. Podocarpaceae y Simaroubaceae se registran por primera vez para la Sierra Madre Occidental. Las principales fuentes de información fueron iNaturalistMX, colectas recientes y omisiones encontradas en la literatura. Noventa y dos de las 130 adiciones cuentan con al menos un registro en iNaturalistMX, de las cuales 31 son registros únicos. Las áreas con más especies añadidas coinciden con regiones poco representadas en las colecciones, históricamente consideradas de baja riqueza por sesgos de colectas.
Conclusiones: La flora de Sinaloa está lejos de conocerse completamente y los sesgos de colectas han producido interpretaciones erróneas en los patrones de su riqueza. El uso de iNaturalistMX y exploraciones recientes permitieron identificar nuevas áreas ricas en biodiversidad.
Parent-teacher partnerships to enhance education for sustainable development: Early childhood development education learning centres in Zimbabwe
Authors: Lunga Prosper
Published: October 2024

Education is one of the fundamental tools necessary to achieve the global Sustainable Development Goals. In particular, Goal 4 advocates for quality education for all since it is important for all children to have a sound educational foundation. In this study, I focus on the second target of Sustainable Development Goal 4 that advocates for early childhood development and universal pre-primary education. The aim of this study was to explore how parent-teacher partnerships could be used to enhance education for sustainable development in early childhood development education learning centres in rural areas. The study was conducted in two primary schools in Bulilima district of Matabeleland, South province in Zimbabwe. The study called on Epstein's notion of parental engagement as the theoretical framework. A participatory action research methodological design was deemed suitable for this qualitative study because it allowed participants to have an opportunity to express their views in their natural settings. Data was generated by means of discussion meetings and reflections and Fairclough's (1992) critical discourse analysis was employed in its analysis. The findings, from early childhood development centres, highlight the importance of teacher-parent partnerships in promoting sustainable learning outcomes and children's well-being. Furthermore, it was found that such partnerships promote alignment between the school culture and the needs of communities and enhance communication and decision making as well as providing a basis for change in the parents' perceptions regarding early childhood development education. The study concluded that teachers and parents should work together at this level of education.
African Indigenous education in the postcolonial period: A critical reflection
Authors: Seroto Johannes , Higgs Philip
Published: October 2024

This article examines African Indigenous education in the precolonial period in Southern Africa, focusing on its key elements, characteristics, and educational significance within the broader context of the decolonial education discourse. By delving into primary forms and practices of Indigenous African education, we aim to shed light on how these systems contribute to understanding the educational landscape and the challenges faced in the wake of colonialism. Additionally, we explore the transformative role played by Indigenous education in Southern Africa in addressing the hegemonic influence of Western education during the postcolonial era. Drawing on existing literature and critical analysis, we critically reflect on the nature of a decolonial turn in African Indigenous education. The examination aims at contributing to the ongoing discourse on decolonising education and providing insights into the potential benefits of embracing Indigenous knowledge systems in contemporary African societies by recognising the importance of valuing diverse knowledge systems in fostering inclusive and relevant educational practices.
Kamsko-Volzhskaya gazeta and Siberian regionalism: Key ideological and practical significance (based on epistolary sources of 1873–1874)
Authors:   Altai State University, Golovinov Aleksandr V. , Dolzhikov Vyacheslav A. ,   Altai State University
Published: October 2024

The aim of this study is to attempt to identify and show the importance of the Kamsko-Volzhskaya gazeta [Kama-Volga Newspaper] (1873–1874) for the formation of the ideology of Siberian regionalism. The authors emphasize that the first socio-political ideals of the leaders of the movement of regionalists Grigory Potanin and Nikolai Yadrintsev were most vividly and comprehensively presented in the Kazan newspaper. The basic concept of provincialism in the ideology of Siberian democratic regionalism was broadly discussed in Kamsko-Volzhskaya gazeta. In general, it is not so much the works of the founders of regionalism that are analyzed, but rather their epistolary heritage. Accordingly, several groups of sources were used for this study and the achievement of its aim: letters, ego-documents, such as autobiographies and memoirs, actual tests of materials prepared by Yadrintsev and Potanin for Kamsko-Volzhskaya gazeta, as well as unpublished archival materials found in Yadrintsev’s archive stored in the Department of Manuscripts and Book Monuments of the Research Library of Tomsk State University. The work done is based on the methodology of the “new cultural and intellectual history”, the principle of historicism and objectivity, and the use of textual content analysis of the sources of this study. Chronologically, the study covers the period 1873–1874 – the time of the regionalism leaders’ active cooperation with the Kazan newspaper. The authors first conducted a small historiographic review of domestic and foreign studies in this area. They showed that the study is relevant because, despite the numerous studies of Yadrintsev’s and Potanin’s ideological heritage, the plot with Kamsko-Volzhskaya gazeta has not been studied enough. In general, the authors note that Potanin’s article “Unification of Regions” and Yadrintsev’s material “The Fate of the Province and the Provincial Question in France”, both published in Kamsko-Volzhskaya gazeta, were of a programmatic nature for Siberian regionalism as an ideology. These works clearly show the federalist and integrative nature of Siberian democratic regionalism. The authors establish that the ideological formulation of the regional program, its conceptualization and even popularization became really possible in Kamsko-Volzhskaya gazeta. Later texts by Yadrintsev and Potanin were also published in other periodicals. However, the purely regionalist discourse was mainly broadcast in the Kazan newspaper. Due to this, the ideology of Siberian regionalism continued to form and even advance.
Divorces based on inability to cohabitate in marriage in the provincial governorates of the Russian Empire
Authors:   Nizhnevartovsk State University, Spichak Aleksandra V. , Vanyushina Olesya V. ,   Research Institute of Information Technologies of the Federal Penitentiary Service of Russia, Krivosheeva Yuliya A. ,   P.G. Demidov Yaroslavl State University
Published: October 2024

The article examines the peculiarities of the process of divorce due to the inability to cohabitate in marriage in the second half of the 19th – early 20th centuries. Based on an analysis of church and secular laws, as well as the opinions of lawyers of the late 19th – early 20th centuries, we established what was meant by “inability to cohabitate in marriage” and justified the inclusion of this problem in the list of permitted reasons for divorce. The main source of the research was the files of the funds of the Tobolsk, Tver and Yaroslavl spiritual consistories preserved in regional archives, as well as the fund of the Office of the Holy Governing Synod. Such a parallel study of one problem in different territories remote from each other made it possible to most thoroughly and fully study the questions posed, to identify common and distinctive features of the divorce process in the center of the Russian Empire and on its periphery. Since spiritual consistories were state institutions, the stages of paperwork in them were identical, and members of the panels strictly followed the law. The time frame for completing cases also turned out to be equally long, it took years to resolve cases positively; a period of up to a year was rather an exception. The time for processing rejected cases depended on the reasons for the refusal and ranged from several days if the documents were incorrectly completed to several months if the illness was not proven. A minority of those who applied, who were mostly women, were able to obtain a divorce. Refusal in half of the cases occurred due to the discovery of the ability to cohabitate in marriage. According to archival documents and the statements of contemporary lawyers, it was much easier to get a divorce for this reason than for the most common one – adultery because the only evidence was the results of a medical examination, the testimony of witnesses was not required, there was no court settlement, admonition took place without unnecessary pressure. However, it cannot be argued that it was easy to get a divorce because, firstly, persons conducting the examination and employees of the consistories and the Synod were quite subjective in assessing the ability to cohabitate in marriage; secondly, shortcomings in the legislation limited applicants in the types and manifestations of the inability itself; thirdly, there were errors when submitting documents and paying fees due to the illiteracy of the population. In Tobolsk Governorate, the eparchy authorities practically deprived poor people of the opportunity to get a divorce for this reason, prohibiting examination by district doctors.
Esquemas Iniciais Desadaptativos como preditores da autoeficácia de pais separados na criação dos filhos
Authors: Cotrim Dayan Moshe Sousa , Da Costa Neto Sebastião Benício
Published: October 2024

OBJETIVO: Identificar se há predições entre os esquemas iniciais desadaptativos e a percepção de autoeficácia de pais e mães separados frente a criação dos filhos. MÉTODO: A abordagem quantitativa, transversal, exploratória, não-experimental, do tipo correlacional foi utilizada como escolha para a análise do estudo; participaram 200 pais, sendo 107 mães e 93 pais, com idade de 21 a 40 anos, com filhos em idade de 0 a 3 anos. Com o estudo aprovado na Comissão de Ética de Pesquisa da Plataforma Brasil, os participantes responderam, além de questões sociodemográficas, ao questionário de esquemas iniciais desadaptativos e a escala de autoeficácia parental (The Self-efficacy for Parenting Tasks Índex – Toddler Scale). RESULTADOS: Observou-se que os pais separados tiveram os esquemas de subjugação, emaranhamento e autossacrifíco correlacionados com a autoeficácia de forma positiva, mas tiveram os esquemas de abandono, defectividade/vergonha, fracasso, vulnerabilidade, padrões inflexíveis e dependencia/incompetência correlacionados de forma negativa com a percepção de autoeficácia dos pais frente a criação de seus filhos. CONCLUSÃO: A pesquisa confirma que os pais e as mães da amostra, mesmo com esquemas primários de abandono, fracasso e defectividade ativados, não se mostraram emocionalmente indisponíveis ou incapazes de formar um vínculo estável e seguro com seus filhos frente as dimensões da autoeficácia, possivelmente, isso ocorreu devido ao aumento da percepção de autoeficácia em relação aos esquemas de autossacrifício, emaranhamento e subjugação, o que, poderiam se relacionar como uma forma secundária de lidar com os esquemas primários.
Effectiveness of the educational program in the knowledge about self-care in renal patients
Authors: Romero Atilano Regina Patricia , Serrano Rojas Flor de María
Published: October 2024

Pre-experimental quantitative research, which aimed to determine the effectiveness of the educational program in the knowledge about self-care of the patient with chronic kidney disease in the Pre-dialysis stage at the Víctor Lazarte Echegaray EsSalud Hospital. The sample population consisted of 35 patients who belonged to the program and who met the selection criteria. For data collection, the “Test on the level of self-care knowledge of the patient with chronic kidney failure” was used, applied before (pre) and after (post) the patient makes use of direct observation of the visual educational material “I take care of myself.” in Pre-dialysis” prepared by the authors based on Dorothea Orem's Self-Care Theory. The intervention was carried out in five moments, and the Student's T test was also used for statistical significance. The results showed that the level of knowledge before the intervention had a poor predominance and in the post-test it was seen that 100% corresponded to a level between regular and efficient, thus concluding that there was 100% effectiveness in the educational program ( p<0.05).
Organizational culture and servant leadership in an agroindustrial company in the Lambayeque region
Authors: Choquepuma Canchari Marnike Esther , Torres Del Águila Sebastián , Erazo Ordoñez Yessica del Rocio
Published: October 2024

The central purpose of this study is to examine how the culture of an agricultural Enterprise the relationship between the culture of an agricultural company and servant-centered leadership. The methodology is based on a fundamental correlational research with a quantitative non-experimental design, the data collection was done through questionnaires adapted and evaluated by means of expert judgment with acceptable levels of reliability, this survey was applied to 117 collaborators. The results indicate a significant correlation between the two (r = 0.429, p < 0.001), highlighting the importance of a solid organizational culture for effective leadership. In addition, positive correlations were found between organizational culture and empowerment (r = 0.404, p < 0.001), collective development (r = 0.346, p < 0.001), empathy (r = 0.224*, p = 0.015) and authentic leadership (r = 0.267**, p = 0.004). These findings suggest that a well-defined organizational culture can strengthen various dimensions of leadership, promoting an engaged and productive work environment.
Extro-Science Fiction and Science Falsity
Authors:   Moscow School of Social and Economic Sciences (MSSES), Likhachevskaya Alina
Published: October 2024

The article presents a critical response to Quentin Meillassoux’s essay Science Fiction and Extro-Science Fiction and proves the impossibility of “fiction of worlds outside- science.” A reconstruction of Meillasoux’s three types of XSF-worlds followed by a demonstration of their failure. Author suggests a shift of emphasis in the notion of “science fiction” from the first word to the second: this move draws attention to the constitutive role of fictitiousness as a characteristic of XSF-worlds rather than their scientific nature. Referring to the philosopher’s earlier works, the author performs a “Ptolemy’s Revenge:” fictional worlds are the product of imagination, which implies the impossibility of decentring thought relative to extro-science fiction. Both classic and contemporary works of the SF are used as illustrations, so the text will be of interest not only to speculative realism researchers, but also to sci-fi fans.
Why Is Love Between People of Different Social Classes Evil? On the Example of the Jack London’s Novel Martin Eden
Authors:   Moscow School of Social and Economic Sciences (MSSES), Karpets Anna
Published: October 2024

The wisdom of classical literature is eternal, which we cannot always say about the love connection between two hearts. At first glance, the Jack London’s novel Martin Eden is a familiar story about the inner strength of a man who is ready to do anything to achieve his goal and how this naive dream breaks into reality. This is a story of unhappy love between a girl from the highest society and an ordinary sailor. I propose to look at this novel from the point of view of the sociology of power and inequality in order to show how our social environment affects us and how the values instilled by society control our views and desires against the will and power of love.
Tutorial on PARADISe: PARAFAC2-based Deconvolution and Identification System for processing GC–MS data v1
Authors: Quintanilla-Casas Beatriz
Published: October 2024

The present protocol provides general guidelines for users working with PARADISe, a deconvolution and identification system for processing GC-MS data. This tool allows users to perform untargeted analysis of large datasets efficiently and minimizes inter-user variability. The final output is a peak table, in excel format, containing the peak area and the purified spectrum for each resolved compound.
Tutorial on PARADISe: PARAFAC2-based Deconvolution and Identification System for processing GC–MS data (version 6.1.x) v2
Authors: Quintanilla-Casas Beatriz
Published: October 2024

The present protocol provides general guidelines for users working with PARADISe, a deconvolution and identification system for processing GC-MS data. This tool allows users to perform untargeted analysis of large datasets efficiently and minimizes inter-user variability. The final outpThe present protocol provides general guidelines for users working with PARADISe, a deconvolution and identification system for processing GC-MS data. This tool allows users to perform nontargeted - also known as untargeted - analysis of large datasets efficiently and minimizes inter-user variability. The final output is a peak table, in excel format, containing the peak area and the purified mass spectrum for each resolved compound. ut is a peak table, in excel format, containing the peak area and the purified spectrum for each resolved compound.
[Proof Reading] West Nile virus NS2B-NS3 protease fusion construct small scale expression and purification protocol v1
Authors: Wang Korvus , fairhead michael , Williams Eleanor
Published: October 2024

This protocol details the co-expression and purification of West Nile virus NS2B-NS3 protease fusion construct bearing a N-terminal His-StrepII tag at small scale (<6L). This protocol produces enzymatically active product that is suitable for biochemical assays.The construct used was QQ01WNVNS2B-c003.
Dengue virus serotype 4 NS2B-NS3 protease fusion construct: 100 mL cultures v1
Authors: fairhead michael , Wang Korvus
Published: October 2024

This protocol details the small scale (100 mL) expression and purification of Dengue virus serotype 4 (DENV-4) NS2B-NS3 protease fusion constructs using the parallel rapid expression and purification (PREPX) method. Recombinant proteins are expressed in Escherichia coli using the autoinduction method and then purified in parallel using a IMAC, desalt, tag cleavage, reverse IMAC and gel filtration work flow. This protocol is adapted from the original PREPX protocol, which is suitable for expressing and purifying multiple constructs in parallel. The protocol can also be adapted for single construct.
Sphaeroptica Manual v1
Authors: Pollet Yann
Published: October 2024

Manual to use Sphaeroptica 1.0, available on GitHub: https://github.com/ypollet/Sphaeroptica
FUNDIS DNA Extraction v2
Authors: Singer Harte
Published: October 2024

A quick and easy DNA extraction protocol for fungal tissue.
A Scoping Review of patient and public trust and acceptance of artificial intelligence (AI) in breast imaging v1
Authors: Kumaran Maya , Shilling Valerie
Published: October 2024

Objective: The objective of this scoping review is to synthesise the current body of knowledge regarding patient and public trust and acceptance of Artificial Intelligence (AI) in breast imaging. Specifically, it aims to identify factors that influence these perceptions and identify gaps in the literature for future research. Introduction: The implementation of AI in breast imaging has demonstrated the potential for improved diagnostic accuracy and faster outcomes, but its success depends heavily on patient and public trust and acceptance. Despite the growing prevalence of AI in healthcare, concerns regarding data privacy, reliability, and transparency may affect how it is perceived. This review will map the existing literature to provide insight into these factors. Inclusion criteria: This scoping review will consider studies focused on patients undergoing breast imaging and the general public’s perspectives on AI in breast imaging. The concept involves trust and acceptance of AI in this medical application, while the context includes any setting where breast imaging occurs. Studies addressing healthcare professionals’ views without including patient or public perspectives, as well as those not using AI, will be excluded. Methods: A comprehensive search strategy (to be conducted in October 2024) will include databases such as Medline,CINAHL, APA PsychInfo and EMBASE, along with grey literature. Studies published in English will be included, and the review will follow the JBI methodology. Two reviewers will independently screen and extract data, with discrepancies resolved by a third reviewer. A thematic analysis will be used to synthesise the findings.
Kelakuan Postur dan Lokomotor Ungka Tangan Putih (Hylobates lar) di Pusat Menyelamat Hidupan Liar Kebangsaan
Authors: Zakariya Nur Nasyuhaa Azwa , Md-Zain Badrul Munir
Published: October 2024

Ungka Tangan Putih (Hylobates lar) merupakan primat Hylobatidae yang sedang diancam kepupusan. Ungka ini mendapat kurang perhatian daripada segi penyelidikan disebabkan faktor kepayahan menjejakinya di lapangan. Oleh itu adalah menarik untuk mengkaji aspek kelakuan Ungka Tangan Putih dalam persekitaran kurungan. Kajian penggunaan ruang, kelakuan postur dan lokomotor Ungka Tangan Putih di pusat pemuliharaan ex-situ belum pernah dikaji. Kefahaman tentang kelakuan yang berkait dengan habitat yang khusus akan meluaskan lagi pemahaman mengenai cara primat bertindak balas terhadap keadaan persekitaran yang berbeza. Objektif utama penyelidikan ini ialah mengkaji penggunaan ruang dalam kurungan dan kanopi serta kelakuan postur dan lokomotor Ungka Tangan Putih di Pusat Menyelamat Hidupan Liar Kebangsaan (NWRC), Sungkai, Perak. Penyelidikan telah dijalankan dengan melakukan pemerhatian fokus ke atas tujuh subjek dari Disember 2021 hingga Mac 2022. Penggunaan ruang kurungan dan kanopi oleh ungka paling tertumpu di bahagian aras tengah (42.37%) berbanding aras atas (24.24%) dan bawah (33.03%). Terdapat 13 jenis kelakuan postur yang ditunjukkan oleh Ungka Tangan Putih iaitu duduk, cangkung, sandar, berpaut, baring, forelimb-suspend, sit/forelimb-suspend, flexed stand/forelimb-suspend, unimanual forelimb suspend, typical forelimb-suspend, forelimb-hindlimb-suspend, hanging upside down dan rocking. Tujuh jenis kelakuan lokomotor yang telah dicerap adalah bipedal, bipedal with hands, quadrupedal walk, brachiate, lompat, bermain dan extended-elbow vertical climb. Postur duduk (18.37%) dan brachiate (50.40%) merupakan kelakuan postur dan lokomotor yang paling kerap diperhatikan. Hasil kajian ini dapat digunakan untuk menambah baik keadaan persekitaran dalaman kurungan Ungka Tangan Putih dalam meningkatkan pengurusan kebajikan ungka dalam kurungan di NWRC.
Study of Natural Herbal Dyes Photodegradation Effect to Optical Properties for Dye-Sensitized Solar Cells
Authors: Triyanto Aripin , Ali Nora’aini , Salleh Hasiah , Setiawan Jan , Yatim Norhafiza Ilyana , Mohd Arifin Nurul Alfatihah , Alias Nur Salihah
Published: October 2024

The stability of natural dyes for use in dye-sensitive solar cells is known from their photodegradation characteristics. Photodegradation effects using artificial light radiation on natural herbal dyes were investigated. Three natural herbal dyes, namely Fagraea acuminatissima, sappanwood, and kulit setong were used in this study. The stability of the natural herbal dyes under artificial light radiation was studied. The optical properties of the natural herbal dyes as indicators of their stability were characterized using FTIR and UV-VIS absorption. Stability testing of natural herbal dyes was conducted in a room with artificial lighting for 5 weeks. Observations of changes in their optical properties were performed weekly. It can be seen that all three natural herbal dyes contained anthocyanin. In addition to anthocyanin, Fagraea acuminatissima and sappanwood also contain chlorophyll. In contrast, the kulit setong contains beta-carotene in addition to anthocyanin. The degradation percentage showed that sappanwood degrade to all of its pigments. While an increase occurred in the chlorophyll peak of Fagraea acuminatissima and the beta-carotene peak of kulit setong. This clearly shows that Fagraea acuminatissima has the highest stability, and potentially increases the efficiency of solar cells.
Fragrance Carrier Based on Zeolite-A Modified Bentonite as a Controlled Release System in Air Freshener Applications
Authors: Kusrini Eny , Usman Anwar , Ayuningtyas Karina , Lee D. Wilson , Putra Nandy , Prasetyo Agus Budi , Rahman Arif , Nugrahaningtyas Khoirina Dwi , Santosa Sri Juari , Noviyanti Atiek Rostika
Published: October 2024

The quality of air fresheners with low cost production can be improved by using a carrier matrix such as synthetic zeolite to increase the long-lasting properties of fragrance product by encapsulation technique. The zeolite A is considerdas a safe core fragrance carrier matrix to be able to release volatile fragrance from their pores when exposed to atmospheric humidity at room temperature. Zeolite A was synthesized from natural kaolin and was formed into tube pellets with bentonite (20 wt.%) as binder to produce zeolite A-bentonite (ZAB) cylindrical pellets composite and used as a fragrance carrier matrix with a rose essential oil (Rose damascena Mill.) as parfume model. The fresh bentonite can also adsorb the rose essential oil with adsorption capacity of 1.745 g/g bentonite (74.5%). Effects of chemical activation on zeolite-A using acid (HCl) of 0.1 M and base (NaOH) of 0.1 M were studied. The ZAB tube pelletes were found to have high adsorption efficiencies of rose essential oil. ZAB4 has the highest efficiency and was used for regeneration test studies that was carried out over 10 cycles using HCl and NaOH, where the adsorption efficiency was 94.5 and 75.4%, respectively. The activated ZAB4 composite using HCl has a long life time until more than 5 weeks and more than 10 regeneration cycles. This fragrance carrier matrix based on ZAB has significant potential for extended carrier fragrance system.
Penilaian Instrumen Pengukuran Strategi Pengurusan Bakat (MyBakat) menggunakan Analisis Model Rasch
Authors: Mohd Nasir Mohammad Fairuz Bin , Mohd Suradi Nur Riza Binti , Ismail Wan Rosmanira Binti
Published: October 2024

Suatu kajian telah dilaksanakan bagi menilai kesahan dan kebolehpercayaan Instrumen Pengukuran Strategi Pengurusan Bakat (MyBakat) dalam sektor awam di Malaysia menggunakan kaedah analisis model Rasch. Kajian ini melibatkan 100 responden yang terdiri daripada pegawai awam persekutuan daripada kategori Pengurusan dan Profesional Gred 41 sehingga Gred 54. Indeks kesahan kandungan adalah 1.00 yang menunjukkan instrumen ini sesuai digunakan. Seterusnya, sepuluh jenis pengukuran analisis model Rasch telah digunakan untuk menilai instrumen MyBakat. Analisis individu menunjukkan sejumlah 42 responden digugurkan dan hanya 58 responden sahaja yang diterima dan dianalisis bersama 25 item dalam MyBakat. Manakala, analisis item pula menunjukkan dua item digugurkan iaitu item Q5 bagi konstruk Pemerolehan Bakat dan Q24 bagi konstruk Pengekalan Bakat. Hasil kajian mencadangkan instrumen MyBakat dengan 23 item sebagai instrumen yang jitu, sah dan boleh dipercayai bagi mengukur strategi pengurusan bakat dalam sektor awam.
Isolation of antibodies to hypochlorite-modified low-density lipoproteins from human serum and study of their specificity
Authors: Grigoryeva Ksenia N. , Dmitrieva Alexandra A. , Ivanova Anna A. , Denisenko Alexander D.
Published: October 2024

BACKGROUND: Modified low-density lipoproteins have immunogenic properties and induce the production of antibodies. In this case, HOCl promotes the formation of subsequent active halogen-containing compounds interacting with proteins and lipid parts of low-density lipoproteins, which leads to their modification and the production of antibodies to them.
AIM: The aim of this work is to isolate antibodies to hypochlorite modified low-density lipoproteins from human blood sera and study their specificity.
MATERIALS AND METHODS: Malondialdehyde, acetic anhydride and sodium hypochlorite were used to obtain modified low-density lipoproteins. IgG antibodies to hypochlorite modified low-density lipoproteins were isolated by affinity chromatography. The total IgG fraction antibodies was previously isolated from human blood serum using MabSelect Xtra. The specific antibodies to hypochlorite modified low-density lipoproteins were isolated from this IgG pool by affinity chromatography. CNBr-Sepharose 4B conjugated with human serum albumin modified with NaOCl was used as a sorbent. The specificity of antibodies against hypochlorite modified low-density lipoproteins was tested using a competitive enzyme-linked immunosorbent assay. The competitors were hypochlorite modified low-density lipoproteins, acetic anhydride modified low-density lipoproteins and malondialdehyde modified low-density lipoproteins in concentrations (1–250 μg/ml).
RESULTS: IgG antibodies against hypochlorite-modified proteins that interact with hypochlorite modified low-density lipoproteins were detected in human blood. According to ELISA date the binding of the isolated antibodies to hypochlorite modified low-density lipoproteins was almost completely inhibited only by appropriately modified low-density lipoproteins, that is, hypochlorite modified low-density lipoproteins, but not native low-density lipoproteins or acetic anhydride modified low-density lipoproteins. Malondialdehyde modified low-density lipoproteins also showed some competitive activity, but much weaker than hypochlorite modified low-density lipoproteins. Hypochlorite modified low-density lipoproteins itself and, to a lesser extent, malondialdehyde modified low-density lipoproteins competed for binding with antibodies of human serum to hypochlorite modified low-density lipoproteins. Acetic anhydride modified low-density lipoproteins and native low-density lipoproteins did not reduce the efficiency of antibody binding to their antigen.
CONCLUSIONS: Hypochlorite modified low-density lipoproteins forms epitopes independent of other low-density lipoproteins modifications studied. These epitopes are responsible for the formation of specific antibodies.