bluuebunny/crossref_metadata_2025 huggingface dataset:
Individualized Colorectal Cancer Screening Discussions Between Older Adults and Their Primary Care Providers: A Cross-Sectional Study
Authors: Kistler Christine E. , Golin Carol , Sundaram Anupama , Morris Carolyn , Dalton Alexandra F. , Ferrari Renee , Lewis Carmen L.
Published: May 2018

Introduction. Discussions of colorectal cancer (CRC) screening with older adults should be individualized to maximize appropriate screening. Our aim was to describe CRC screening discussions and explore their associations with patient characteristics and screening intentions. Methods. Cross-sectional survey of 422 primary care patients aged ≥70 years and eligible for CRC screening, including open-ended questions about CRC screening discussions. Primary outcomes were the frequency with which CRC screening discussions occurred, who had those discussions, and the domains that emerged from thematic analysis of participants’ brief reports of their discussions. We also examined the associations between 1) patient characteristics and whether a screening discussion occurred and 2) the domains discussed and what screening decisions were made. Results. Of 422 participants, 209 reported having discussions and 201 responded to open-ended questions about CRC discussions. In a regression analysis, several factors were associated with increased odds of having a discussion: participants’ preference to pursue screening (odds ratio [OR] 2.3, 95% confidence interval [CI] 1.3, 3.9), good health (OR 2.9, 95% CI 1.7, 4.8), and receipt of the decision aid (OR 2.1, 95% CI 1.4, 3.2). Our thematic analysis identified five domains related to discussion content and three related to discussion process. The CRC screening–related information domain was the most commonly discussed content domain, and the timing/frequency domain was associated with increased odds of intent to pursue screening. Decision-making role, the most commonly discussed process domain, was associated with increased odds of the intent to forgo CRC screening. Conclusions and Relevance. CRC screening discussions varied by type of participant and content. Future work is needed to determine if interventions focused on specific domains alters the appropriateness of participants’ colorectal cancer screening intentions.
A Comparative Study of the Effects of Nigella sativa Oil Gel and Aloe Vera Gel on Wound Healing in Diabetic Rats
Authors: Sari Yunita , Purnawan Iwan , Kurniawan Dhadhang Wahyu , Sutrisna Eman
Published: May 2018

Clinicians and wound care nurses in Indonesia usually use Nigella sativa oil (NSO) gel and aloe vera (AV) gel to treat diabetic ulcers. However, there are no studies directly comparing the effects of NSO and AV gels on wound healing, so it is unknown which of these 2 plants is better at promoting wound healing in diabetic ulcers. If the comparative efficacy between these 2 gels was known, it would be important evidence favoring the clinical use of one or the other product in Indonesia. The aim of this study was to investigate and compare the effectiveness of NSO and AV gels on wound healing in a rat model of diabetic ulcers. This experimental study involved 3 groups: NSO gel, AV gel, and controls. Our study showed that from day 5 onward, necrotic tissue and inflammation decreased in the AV gel group compared with the other groups. The wound areas on days 6 ( P = .020) and 7 ( P = .021) were significantly smaller in the AV gel group than in the NSO gel group. Reepithelialization was also better in the AV gel group than in the other groups. This is the first study to compare the effects of AV and NSO gels on wound healing in diabetic ulcers. Our study indicates that the AV gel is better than the NSO gel. Therefore, it is recommended that clinicians and wound care nurses use AV gel instead of NSO gel for the topical treatment of diabetic ulcers.
Termination of SUNCT with intravenous lignocaine followed by oral mexiletine
Authors: Mulroy Eoin , Armstrong-Scott Oliver , Bergin Peter
Published: May 2018

Background:

The trigeminal autonomic cephalalgias (TACs) are a group of debilitating, pathophysiologically similar headache syndromes characterized by facial pain and autonomic symptoms in areas supplied by the trigeminal nerve. Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) is among the rarest of the TAC syndromes and can be particularly recalcitrant to treatment.

Case:

We describe the case of a 50-year old woman with difficult-to-control SUNCT whose pain was completely aborted within hours of commencing intravenous lignocaine therapy and was maintained pain-free after transitioning to oral mexiletine.

Conclusion:

This is the first report of successful transition from intravenous lignocaine to oral mexiletine in SUNCT, and we suggest that this treatment should be tried early in difficult-to-control SUNCT. This therapy is safe, effective and with minimal side effects if administered in an appropriate manner.
Beyond Preservice Special Educators: Embedding Assistive Technology Content Throughout a Teacher Education Program of Study
Authors: King Laura H. , Allen Ayla E.
Published: May 2018

Knowledge and understanding of assistive technology is important for all education majors as they prepare to serve increasingly diverse classrooms. This article provides a program description of how one rural university embedded assistive technology content and skills in both a special education plan of study, as well as in professional core courses for all education majors. The process and model are described for both on-campus and distance education populations. In addition, strengths and challenges of the model are discussed.
Rapid immune reconstitution of SCID-X1 canines after G-CSF/AMD3100 mobilization and in vivo gene therapy
Authors: Humbert Olivier , Chan Frieda , Rajawat Yogendra S. , Torgerson Troy R. , Burtner Christopher R. , Hubbard Nicholas W. , Humphrys Daniel , Norgaard Zachary K. , O’Donnell Patricia , Adair Jennifer E. , Trobridge Grant D. , Scharenberg Andrew M. , Felsburg Peter J. , Rawlings David J. , Kiem Hans-Peter
Published: May 2018

Key Points

IV delivery of FV vector using the phosphoglycerate kinase promoter outperforms EF1α-containing vector in the canine SCID-X1 model. G-CSF/AMD3100 mobilization before in vivo FV vector delivery improves kinetics and clonal diversity of lymphocyte reconstitution.
Efficacy and safety profile of xanthines in COPD: a network meta-analysis
Authors: Cazzola Mario , Calzetta Luigino , Barnes Peter J. , Criner Gerard J. , Martinez Fernando J. , Papi Alberto , Gabriella Matera Maria
Published: May 2018

Theophylline can still have a role in the management of stable chronic obstructive pulmonary disease (COPD), but its use remains controversial, mainly due to its narrow therapeutic window. Doxofylline, another xanthine, is an effective bronchodilator and displays a better safety profile than theophylline. Therefore, we performed a quantitative synthesis to compare the efficacy and safety profile of different xanthines in COPD.

The primary end-point of this meta-analysis was the impact of xanthines on lung function. In addition, we assessed the risk of adverse events by normalising data on safety as a function of person-weeks. Data obtained from 998 COPD patients were selected from 14 studies and meta-analysed using a network approach.

The combined surface under the cumulative ranking curve (SUCRA) analysis of efficacy (change from baseline in forced expiratory volume in 1 s) and safety (risk of adverse events) showed that doxofylline was superior to aminophylline (comparable efficacy and significantly better safety), bamiphylline (significantly better efficacy and comparable safety), and theophylline (comparable efficacy and significantly better safety).

Considering the overall efficacy/safety profile of the investigated agents, the results of this quantitative synthesis suggest that doxofylline seems to be the best xanthine for the treatment of COPD.
The role of cardiopulmonary exercise tests in pulmonary arterial hypertension
Authors: Farina Stefania , Correale Michele , Bruno Noemi , Paolillo Stefania , Salvioni Elisabetta , Badagliacca Roberto , Agostoni Piergiuseppe
Published: May 2018

Despite recent advances in the therapeutic management of patients affected by pulmonary arterial hypertension (PAH), survival remains poor. Prompt identification of the disease, especially in subjects at increased risk of developing PAH, and prognostic stratification of patients are a necessary target of clinical practice but remain challenging. Cardiopulmonary exercise test (CPET) parameters, particularly peak oxygen uptake, end-tidal carbon dioxide tension and the minute ventilation/carbon dioxide production relationship, emerged as new prognostic tools for PAH patients. Moreover, CPET provides a comprehensive pathophysiological evaluation of patients' exercise limitation and dyspnoea, which are the main and early symptoms of the disease. This review focuses on the role of CPET in the management of PAH patients, reporting guideline recommendations for CPET and discussing the pathophysiology of exercise limitation and the most recent use of CPET in the diagnosis, prognosis and therapeutic targeting of PAH.
State of the art in interstitial pneumonia with autoimmune features: a systematic review on retrospective studies and suggestions for further advances
Authors: Sambataro Gianluca , Sambataro Domenico , Torrisi Sebastiano Emanuele , Vancheri Ada , Pavone Mauro , Rosso Roberta , Schisano Matteo , Crimi Claudia , Pignataro Francesca , Fischer Aryeh , Del Papa Nicoletta , Vancheri Carlo
Published: May 2018

The term interstitial pneumonia with autoimmune features (IPAF) has been proposed to define patients with interstitial lung disease (ILD) associated with autoimmune signs not classifiable for connective tissue diseases (CTDs). This new definition overcomes previous nomenclatures and provides a uniform structure for prospective studies through specific classification criteria.

This work evaluates the characteristics of IPAF patients reported in the literature, to highlight potential limits through a comparative analysis and to suggest better performing classification criteria.

Four retrospective studies on the IPAF population have been considered. The study subjects differed in age, sex, smoking habit, ILD pattern and outcomes. Another important difference lies in the diverse items considered in the classification criteria. The retrospective design of the studies and the absence from some of them of a rheumatologist clearly involved in the diagnosis may have influenced the data, but current IPAF criteria seem to include a rather heterogeneous population. To overcome these discrepancies, this review suggests a limitation in the use of single items and the exclusion of extremely specific CTD criteria. This should avoid the definition of IPAF for those diseases at different stages or at early onset. The investigation of a functional or morphological cut-off of pulmonary involvement would be useful.
Scientific analysis of tie luo, a Qing Dynasty calligraphy artifact in the Palace Museum, Beijing, China
Authors: Wei Le , Chen Wenjia , Jin Gaowa , Guo Zhimou , Wang Yunli , Kang Baoqiang , Wang Na , Gu An , Zhang Yun , Lei Yong
Published: May 2018

Tie luo (affixed hanging) was an expressive form of traditional Chinese calligraphy or paintings, and popular in the imperial palaces for interior decorations in Qing Dynasty (1644–1911 C.E.). A piece of calligraphic tie luo, written by an eminent calligrapher Gu Gao (1763–1832 C.E.), was restored recently in the Palace Museum, Beijing, China. The paper with pigment coating specially made for this calligraphic piece was named as fenjian. This article presented results from materials identification prior to the restoration. Multianalysis with scientific approaches revealed how tie luo was manufactured. It could be concluded that the investigated tie luo used a paper made from bast fibers of mulberry trees. And the decorative ground layer for the piece was also studied, which indicated that a type of organic red pigments were used for the masterpiece. White lead was considered as the main pigment, mixed with a red dye extracted from sappanwood. Meanwhile, animal glue, drying oils and beeswax were confirmed as the organic binding media. In dye analysis, protosappanin B and brazilin as well as brazilein were identified, which implied that sappanwood was used for the organic manufacture of pigments. In addition, both Nowik type A and C were found in the research, which were characteristic of sappanwood for identification.
Armed conflict and mental health in Colombia
Authors: Tamayo-Agudelo William , Bell Vaughan
Published: May 2018

Although significant progress has been made in the peace process, Colombia still experiences high levels of ongoing violence and a legacy of more than five decades of armed conflict. Epidemiological studies show markedly raised levels of mental health problems in people affected by the conflict, with internally displaced people being a large and important group with unmet needs. Provision of mental health services is uneven and subject to significant underinvestment. Priority mental health treatment for victims of the conflict is now established in law, although the effectiveness of these programmes has yet to be established.
All in the family: proneural bHLH genes and neuronal diversity
Authors: Baker Nicholas E. , Brown Nadean L.
Published: May 2018

Proneural basic Helix-Loop-Helix (bHLH) proteins are required for neuronal determination and the differentiation of most neural precursor cells. These transcription factors are expressed in vastly divergent organisms, ranging from sponges to primates. Here, we review proneural bHLH gene evolution and function in the Drosophila and vertebrate nervous systems, arguing that the Drosophila gene atonal provides a useful platform for understanding proneural gene structure and regulation. We also discuss how functional equivalency experiments using distinct proneural genes can reveal how proneural gene duplication and divergence are interwoven with neuronal complexity.
System dynamic modelling of electricity planning and climate change in West Africa
Authors: Momodu Abiodun S. , Kivuti-Bitok Lucy
Published: May 2018

Background: It is imperative to develop an efficient strategic approach to managing the push-pull factor in economic development, particularly as relates to climate change and energy interactions in the West African Region. This article demonstrates the use of System Dynamics Modelling (SDM) for that purpose; to manage the development of energy growth with reduced impact in regards to climate change. The complexities of energy planning in relation to climate change necessitates the need for the tool to examine low carbon economy mixed with traditional approaches of planning.

Methods: Vensim DSS version 6.2 was used to develop the model. WAPP member country level data elicited from WAPP and ECOWAS Regional Electricity Regulatory Authority (ERERA) serves as the set of basic data used to develop and run the main model. These were complemented with other data elicited from various journal articles and internet sources. These include population and its average growth rate, GDP, per capita income, average per capita electricity demand, electricity generated, average electricity tariff, generation technology type, amongst others.

Results: SDM demonstrates the capability to understand the theoretical frame for trade-offs between economic development and climate change, by handling the nonlinear relationship between generation adequacy and greenhouse gas (GHG) emission reduction for better targeted strategic regional intervention on climate change.

Conclusion: The primary goal of this paper was to demonstrate the use of SDM to aid in resource planning in an inexpensive way to examine low carbon pathway. With the SDM, the goal of low carbon pathway in the energy system was achieved without the cost of controlled trials.
The Zambian Preterm Birth Prevention Study (ZAPPS): Cohort characteristics at enrollment
Authors: Castillo Marcela C. , Fuseini Nurain M. , Rittenhouse Katelyn , Price Joan T. , Freeman Bethany L. , Mwape Humphrey , Winston Jennifer , Sindano Ntazana , Baruch-Gravett Courtney , Chi Benjamin H. , Kasaro Margaret P. , Litch James A. , Stringer Jeffrey S. A. , Vwalika Bellington
Published: May 2018

Background: Sub-Saharan Africa bears a disproportionate burden of preterm birth and other adverse outcomes. Not only is the background rate of preterm birth higher than in North America and Europe, but many facilities lack essential equipment and personnel resources to care for preterm neonates. A better understanding of the demographic, clinical, and biologic underpinnings of preterm birth is urgently needed to plan interventions and inform new discovery. 

Methods: The Zambian Preterm Birth Prevention Study (ZAPPS) is a prospective antenatal cohort established at the Women and Newborn Hospital of the University Teaching Hospital (UTH) in Lusaka, Zambia. We recruit pregnant women from the antenatal clinics of district health centers and the UTH for study participation. Women undergo ultrasound examination to determine eligibility by gestational age criteria. Enrolled participants receive routine antenatal and postnatal care, lab testing, midtrimester cervical length measurement, serial fetal growth monitoring and careful assessment of birth outcomes. 

Results: Between August 2015 and September 2017, we screened 1784 women, of whom 1450 (81.2%) met inclusion criteria and were enrolled. The median age at enrollment of study participants is 27 years (IQR 23–32). Participants are enrolled at a median gestational age of 16 weeks (IQR 13–18). Among all parous participants (N=866; 64%), 21% (N=182) reported a prior miscarriage, 49% (N=424) reported a prior preterm birth, and 13% (N=116) reported a prior stillbirth. The HIV seroprevalence in our cohort is 24%.

Discussion: We have established a large antenatal cohort to characterize the epidemiological and biological determinants of adverse birth outcomes in Lusaka, Zambia. Findings from this cohort will help guide future studies, clinical care, and policy in the prevention and treatment of adverse birth outcomes.
A apropriação da hermenêutica por Heidegger nos anos 1920
Authors: Fernandes Christiane Costa de Matos
Published: May 2018

O Trabalho pretende expor a apropriação da hermenêutica realizada por Heidegger no percurso dos anos 1920 até a obra Ser e Tempo. A exposição pretende marcar a contribuição de Dilthey e as transformações realizada por Heidegger a partir do redimensionamento da pergunta pelo sentido de ser.
La Noche Oscura como misteriofanía negativa. Hacia una ontología fenomenológica del acontecimiento de lo divino, en la Subida del Monte Carmelo, de San Juan de la Cruz
Authors: González Suárez Lucero
Published: May 2018

El presente artículo es un análisis fenomenológico de la Subida del Monte Carmelo, cuyo propósito es mostrar que la Noche Oscura es una misteriofanía negativa que acoge tres sentidos. En primer lugar, San Juan de la Cruz llama Noche Oscura a la negación de los apetitos relativos a las potencias. En segundo lugar, la fe es Noche Oscura para el hombre, porque la donación de lo divino causa ceguera en el entendimiento. Finalmente, Dios es Noche Oscura para el hombre debido a que su manifestación es invisible. La intención de estas páginas es hacer algunas aportaciones a la fenomenología de la experiencia mística cristiana, cuyos conceptos fundamentales tienen un doble origen: la fenomenología contemporánea y la fenomenología de la religión y de la mística, desarrollada principalmente por la escuela española.This article is an original phenomenological analysis of the Ascent of Mount Carmel, whose purpose is to show that Dark Night is a negative mysteriophany, which implies three senses. First of all, Saint John of the Cross calls Dark Night the denial of the appetites of the faculties. Second, faith is Dark Night to humankind because the donation of the divine causes blindness in the understanding. Finally, God is Dark Night for men, because his manifestation is invisible. The intention of those pages is to make some contributions to phenomenology of Christian mysticism, whose fundamental concepts have a dual origin: contemporary phenomenology and the phenomenology of religion and mysticism, developed mainly by the Spanish school.
MERLEAU-PONTY E O “RETORNO ÀS COISAS MESMAS”: A INERÊNCIA CORPORAL RETIRADA DA FENOMENOLOGIA HUSSERLIANA
Authors: Warmling Diego Luiz
Published: May 2018

Das leituras de Merleau-Ponty sobre Husserl, este artigo discute como a fenomenologia transcendental põe-se fora da empiria ao desvelar a consciência como domínio apodítico e defender a formulação de condições universais para qualquer experiência concreta. Sendo impossível abandonar o primado do corpo, Merleau-Ponty alerta para a inviabilidade de retirarmo-nos totalmente dos envolvimentos mundanos, entendendo que a filosofia transcendental precisa saber seus limites e não abandonar seu caráter de incompletude. O francês remaneja as teses husserlianas e redefine as noções de consciência e representação sem, todavia, suprimir a experiência da encarnação. Admitindo uma promiscuidade entre o empírico e o ideal, é a partir do corpo que encontraremos esta inserção primordial pela qual estamos envolvidos com o transcendental. Será no paradoxo do corpo enquanto consciência e experiência integrativa do homem no movimento do ser-no-mundo que compreenderemos as intenções racionais e vitais.
A woman's cry for her midwife
Authors: Dunkley-Bent Jacqueline
Published: May 2018

Two years on from the launch of the National Maternity Review's Better Births document, Jacqueline Dunkley-Bent OBE provides a unique reflection of her 30-year midwifery career
The issue of consent
Authors: Axcell Claire
Published: May 2018

In her former career as a police officer, Claire Axcell was well-versed in the meaning of ‘consent’ and how it worked in practice. She considers how it applies to maternity care
Two cases of canine exophthalmos
Authors: Pennington Catrina , Gallagher Barbara
Published: May 2018

Two Labrador Retrievers presented with a similar history of sudden-onset, unilateral exophthalmos. Advanced imaging diagnostics showed similar findings; however their final diagnoses differed markedly. The first case was an 8-year-old, male-neutered dog who was diagnosed with bilateral zygomatic sialadenitis, worse on the left and subtly present on the right. The second case was a 1-year-old female-entire, subsequently diagnosed with acquired coagulopathy. Both cases responded to medical management. These cases emphasise the range of conditions that need to be considered when presented with a case of exophthalmos.
Pancreatic cancer: A guide for practice nurses
Authors: Perry Margaret Ann
Published: May 2018

Although rare, pancreatic cancer usually has a poor prognosis. Margaret Ann Perry explains the risk factors for, and diagnosis and treatment of, the disease

Despite improved survival for those with many types of cancer, pancreatic cancer has continued to have poor outcomes. This article was written following the loss of a popular and well respected colleague who recently passed away from this devastating disease. It aims to alert practice nurses to the vague symptoms of pancreatic cancer, its diagnosis and management, and improve knowledge and understanding of this much-feared cancer type.
Treating eczema in children in general practice
Authors: Onselen Julie Van
Published: May 2018

Atopic eczema is very common and the vast majority of children are treated in primary care. Julie Van Onselen highlights the key role practice nurses can play in helping to manage eczema

Atopic eczema is very common in children and the vast majority are treated in primary care. Atopic eczema management mirrors management of chronic asthma in primary care. Practice nurses are well placed to be ‘atopic nurses’ and assess, educate and treat children with atopic eczema, in a framework of chronic disease management, as they do in asthma management. This article gives information on assessment, the stepped approach to atopic eczema management, and discusses adherence and education of parents/carers, children and families.
Placements in general practice: Perspectives from a NQN
Authors: Porter Lucy
Published: May 2018

A placement in general practice encouraged Lucy Porter to become a practice nurse after qualifying. Here she shares the challenges and rewards of being a newly qualified nurse (NQN) in general practice
Increased Insulin-like Growth Factor Binding Protein-1 Phosphorylation in Decidualized Stromal Mesenchymal Cells in Human Intrauterine Growth Restriction Placentas
Authors: Singal Sahil S. , Nygard Karen , Gratton Robert , Jansson Thomas , Gupta Madhulika B.
Published: May 2018

Intrauterine growth restriction (IUGR) is often caused by placental insufficiency, which is believed to be associated with decreased delivery of oxygen and nutrients to the placental barrier. We recently reported that hypoxia and/or leucine deprivation triggered hyperphosphorylation of insulin-like growth factor binding protein-1 (IGFBP-1) in decidualized human immortalized endometrial stromal cells (HIESCs), resulting in decreased insulin-like growth factor-1 (IGF-1) bioactivity. To test the hypothesis that human IUGR is associated with increased decidual IGFBP-1 phosphorylation at discrete sites, we used IUGR and gestational age matched appropriate for gestational age (AGA) placentas ( n=5 each). We performed dual immunofluorescence immunohistochemistry (IHC) using IGFBP-1 and vimentin as decidual and mesenchymal markers, respectively. Employing a unique strategy with imaging software, we extracted signal intensity of IGFBP-1 expressed specifically from truly decidualized cells of the placenta. Relative IGFBP-1 was increased (85%; p=0.0001) and using custom phospho-site-specific antibodies, we found that IGFBP-1 phosphorylation (pSer101; +40%, p=0.0677/pSer119; +60%, p=0.0064/pSer169; +100%, p=0.0021) was markedly enhanced in IUGR. Together, our data links for the first time, increased decidual IGFBP-1 phosphorylation at discrete sites with human IUGR. These novel findings suggest that hyperphosphorylation of IGFBP-1 in decidualized stromal mesenchymal decidua basalis contributes to potentially elevated levels of phosphorylated IGFBP-1 in maternal circulation in IUGR pregnancies.
La auditoria sociolaboral y sus grupos de interés: ¿intereses comunes? ¿intereses compartidos?
Authors: Calvo Ricard , Sigalat Enric , Rodríguez Juan A.
Published: May 2018

La auditoría sociolaboral es una herramienta de gestión del personal, los recursoshumanos y las relaciones laborales, desconocida para la mayoría de organizaciones.Es una apuesta técnica de futuro capaz de aportar beneficios muy amplios yvariados, tanto para los encargados de gestionar directamente las mismas como indirectamentepara todos aquellos que pueden verse afectados por ella. El presente artículoahonda en ello planteando como cuestión de debate el análisis del grado decoincidencia existente entre las visiones que los distintos actores tienen de las dificultadesde aplicación de la auditoría sociolaboral como herramienta de gestión delos recursos humanos y las relaciones laborales. Para ello toma como base empíricalos resultados obtenidos hasta el momento en una investigación desarrollada desdela Universitat de València, donde a partir del estudio de casos de dos empresas se hapodido analizar dicho grado de coincidencia.
Prólogo
Authors: López Rubia M.Edurne
Published: May 2018

Con animo de conmemorar el decimo aniversario de la Ley Organica3/2007, de 22 de marzo, para la igualdad efectiva de mujeres y hombres (LOI)y dejar patente la necesidad de seguir trabajando en pro de la igualdad entremujeres y hombres, el 21 y 22 de septiembre se llevo a cabo, en el marco de losCursos de Verano de la Universidad Publica de Navarra (UPNA), el curso tituladoNuevos retos en materia de igualdad laboral tras diez años de aprobación dela LOI, organizado por el Departamento de Derecho Privado y dirigido por laprofesora Dna. Elisa Sierra Hernaiz (Titular de Derecho del Trabajo y de la SeguridadSocial, UPNA).
De la igualdad de oportunidades a la igualdad de resultados: la educación aún no es suficiente garantía para las mujeres.
Authors: Gomez Perez Amaia
Published: May 2018

Este artículo tratará de contrastar en la Comunidad Autónoma Vasca (CAV)la brecha existente entre el nivel de formación de las mujeres y el nivel de rentas quealcanzan posteriormente. A pesar de que el sistema educativo intente equilibrar lasoportunidades para cada persona individual, las mujeres no obtienen los mismosresultados que los hombres, a falta de una justicia social que equipare a mujeres yhombres realmente. Las estadísticas e indicadores ofrecen la evidencia de esta falta decorrespondencia entre la participación que mantienen las mujeres primero, en la formaciónacadémica y posteriormente en el ámbito laboral. La clave que subyace paraque tales desigualdades existan es que el aspecto de género discrimina a la mujer, impidiendouna igualdad real y efectiva.
Nuevos retos de las prestaciones de la Seguridad Social por maternidad y paternidad.
Authors: Llorens Espada Julen
Published: May 2018

En el presente trabajo se realiza un estudio del estado actual de las prestacionesde la Seguridad Social por maternidad y paternidad, diez años después de la promulgaciónde la LOI. Ello se realiza desde una visión integradora de la más recientedoctrina jurisprudencial nacional y europea, lo cual lleva el estudio a supuestos deactual litigiosidad como el disfrute del permiso de maternidad por «el otro progenitor» o los casos de maternidad subrogada y el reconocimiento de las prestaciones dematernidad para estos casos. Con todo ello, el estudio pretende arrojar algo de luz enel camino hacia un marco equitativo de corresponsabilidad e involucración efectivade ambos sexos.
Diversidad de género como parte de la RSC y sostenibilidad en las empresas. Avances para la mejora de la divulgación de información no financiera sobre las políticas de igualdad y sus resultados
Authors: Saitua Iribar Ainhoa
Published: May 2018

El número cinco de los 17 Objetivos de Desarrollo Sostenible (ODS) de las Naciones Unidas, tal como se aprobaron en 2015, consiste en lograr una igualdad de género efectiva, objetivo que debe promoverse también en el ámbito empresarial. Por otra parte, cada vez es mayor la demanda de transparencia sobre los impactos que genera la actividad de las organizaciones y sobre la propia gobernanza de éstas, como parte de la Responsabilidad Social Corporativa (RSC). Este artículo revisa las principales iniciativas que se están dando para avanzar en la normalización de la divulgación sobre políticas de igualdad en las organizaciones, especialmente, la Comunicación de la Comisión Europea (CE, 2017b), de directrices o guía para ayudar a las empresas que deban aplicar la Directiva 2014/95/EU por primera vez en2018. Si bien, en la medida en que la aplicación de la guía será voluntaria, no está garantizada su aplicación por parte de las empresas. También se revisa la guía publicada por la red para liderazgo de la dirección financiera Accounting for Sustainability (A4S, 2017). Como resultado se constata que los ejemplos que ofrecen las empresas que pueden actuar como líderes en la divulgación de políticas de diversidad de género son aún muy escasos. Por lo tanto, creemos que es necesario seguir trabajando en este área que, hasta el presente, no se ha abordado suficientemente, ni en la literatura contable ni en la práctica de las empresas.
ESTRATÉGIAS COMPETITIVAS USADAS PELAS EMPRESAS DE EVENTOS DE CURITIBA
Authors: Maioli Marcos Rogério , Stadler Adriano , Ardigo Carlos Marcelo
Published: May 2018

Este artigo apresenta como duas empresas de organização de eventos de Curitiba Paraná atuam no mercado, como utilizam seus conhecimentos de gestão de forma empírica quando usam as estratégias de competitividade de Porter e Ansoff para atuarem no mercado e fazerem frente as mudanças ambientais ocorridas. Os principais resultados podem ser encontrados no uso das estratégias que fazem frente aos concorrentes, aos serviços substitutos, ao poder de barganha tanto de clientes, fornecedores e aos novos entrantes, também no uso de estratégias de expansão e diversificação. O trabalho está dividido em introdução, fundamentação em turismo, eventos, estratégias competitivas de Porter e Ansoff, a caracterização das empresas estudadas, a metodologia usada a apresentação dos resultados e as conclusões
PROJETO DE EXTENSÃO LUDOTECA DO TURISMO: A ELABORAÇÃO E APLICAÇÃO DE JOGOS LÚDICO-Pedagógicos Junto a Escola da Inclusão da UFPel
Authors: Lessa Roberta Mattos , Resende Leonardo Ferreira , Silva Priscilla Teixeira da , Minasi Sarah Marroni
Published: May 2018

Este trabalho tem como objeto de estudo a elaboração de jogos lúdico-pedagógicos para trabalhos de sensibilização nas áreas de turismo e patrimônio junto a pessoas com deficiência. Neste contexto, o objetivo geral do presente estudo é apresentar os dois jogos desenvolvidos pelo Projeto de Extensão “Ludoteca do Turismo”, do Curso de Bacharelado em Turismo da Universidade Federal de Pelotas (UFPel), a partir da experiência de trabalho com o grupo de alunos da Escola da Inclusão da UFPel no ano de 2016. Para isso, foram realizadas pesquisa bibliográfica, pesquisa documental e pesquisa de campo, com a realização de entrevistas com alunos, pais e organizadores da Escola da Inclusão. Com base na análise realizada pode-se concluir que o “Bingo dos Patrimônios” foi o jogo que mais chamou atenção, com o uso de imagens em tamanho grande para que toda a turma, independente da idade ou da deficiência, pudesse participar, tornando a ação, de fato, lúdica e inclusiva.
ROTEIROS TURÍSTICOS DA REGIÃO CENTRAL DO RIO GRANDE DO SUL – Estudo sobre as Principais Características e Atrativos aos Turistas
Authors: Righi Dotto Dalva Maria , Coradini Cerezer Lilian , Dias Pons Monica Elisa , Menezes Denardin Adriele Carine
Published: May 2018

Um roteiro turístico caracteriza-se pela convergência de ações e de atrativos aos turistas numa determinada localidade ou região. Considerado importante para dinamizar o setor de turismo, os roteiros turísticos necessitam ser planejados, organizados e promovidos de forma adequada para atrair os turistas. Nesta perspectiva, este estudo objetiva mapear os roteiros turísticos da Região Central do estado do Rio Grande do Sul (RS) e, mais especificamente, verificar a localização/região em que estão organizados e as características principais destes roteiros. Como procedimento metodológico utilizou-se a abordagem exploratória, com uma pesquisa qualitativa. Observou-se que na região estudada ainda existem poucos roteiros turísticos organizados, com predominância de utilização dos recursos naturais como principal atrativo turístico.
GESTÃO DA EXPERIÊNCIA EM SERVIÇO DE HOSPITALIDADE: Análise das Avaliações de Hospedagens do Village Confort Hotel e Flat em João Pessoa / PB
Authors: Brito Thiago Vinícius Pereira de , Silva Márcia Félix da , Silva Nicole Cavalcanti
Published: May 2018

Nos últimos anos, o mercado hoteleiro brasileiro vem passando por importantes transformações para atender aos desejos de um consumidor bem informado e, por consequência, bem mais exigente. A busca por mais qualidade nos serviços oferecidos pelos meios de hospedagem, aliada à disseminação do uso da Internet têm contribuído para essa mudança de comportamento do consumidor que busca obter uma experiência positiva em relação à satisfação dos seus desejos e expectativas. Nesse sentido, este estudo buscou analisar a relação da experiência em serviços de hospitalidade e as diretrizes tomadas pelo Village Confort Hotel e Flat, localizado em João Pessoa- PB, a partir dos comentários (positivos e/ou negativos) registrados pelos hóspedes, por meio dos mecanismos de avaliação dos serviços. A pesquisa realizada foi do tipo exploratória, descritiva de abordagem quanti-qualitativa, conduzida sob a forma de um estudo de caso. Foram coletados dados primários e secundários em sítios de compras de hospedagem na Internet e no próprio estabelecimento através de fichas avaliativas e do feedback eletrônico. Os resultados mostraram que diante da intangibilidade do produto turístico, a experiência em serviços de hospitalidade é influenciada pela maneira como os gestores direcionam ações visando solucionar problemas ou maximizar oportunidades quando tem o conhecimento das reclamações e dos elogios apresentados pelos hóspedes.
Bekommt der zahnlose Tiger endlich Zähne?
Authors: Heydenreich Cornelia
Published: May 2018

Die OECD-Leitsätze für multinationale Unternehmen sind eines der wichtigsten Instrumente für globale Unternehmensverantwortung. Bei ihrer Anwendung haben sich jedoch gravierende Schwächen gezeigt. Die aktuelle Überarbeitung bietet nun eine Chance, die Leitsätze zu einem wirksameren Instrument auszugestalten.
El castellano del Caribe colombiano en la ciudad de Nueva York: El uso variable de sujetos pronominales
Authors: Orozco Rafael
Published: May 2018

Este estudio de la expresión de pronombres personales de sujeto entre hablantes del castellano caribeño colombiano en Nueva York revela una tasa pronominal (43 %) significativamente más alta que la existente en el Caribe colombiano. Los resultados descubren que cinco predictores lingüísticos y dos sociales condicionan la expresión pronominal. Los predictores lingüísticos – entre los cuales persona y número del sujeto condiciona más fuertemente el uso pronominal – revelan tendencias similares a las existentes alrededor del mundo hispánico. Los predictores sociales reflejan aumentos significativos en las tasas pronominales tanto de mujeres como de hombres en los diferentes grupos etarios analizados y también entre los recién llegados a Nueva York. Aunque existen similitudes superficiales con el resto del mundo en los efectos condicionantes internos, un análisis minucioso de los efectos del verbo descubre tendencias opuestas entre verbos agrupados en una misma categoría semántica; por ejemplo,irfavorece los sujetos expresos perosalirlos tácitos. Esto implica que clasificaciones basadas en criterios semánticos no constituirían la manera óptima de explorar los efectos del verbo en la expresión pronominal. Además, la tasa pronominal significativamente más alta entre los recién llegados tiene implicaciones metodológicas sugiriendo que estos hablantes no proporcionarían una muestra fidedigna de la expresión pronominal en sus comunidades de origen.
“You Can Never Give Up Siyez If You Taste It Once”: Local Taste, Global Markets, and the Conservation of Einkorn, an Ancient Wheat
Authors: Atalan-Helicke Nurcan
Published: May 2018

Einkorn (Triticum monococcum), locally known as siyez in northwest Turkey, is a hulled wheat variety. It is a semi-wild relative of wheat and is considered one of the Neolithic founder crops of agriculture, along with emmer and barley. Grown in the ancient Near East for at least eight thousand years, its production today is limited to marginal mountainous and isolated communities in different countries of the Mediterranean region. This article examines the expansion of einkorn markets in Turkey, an important wheat exporting and processing country, which has created increased income opportunities for small farmers in Ihsangazi, Kastamonu. Although einkorn already fits into the broad dietary habits of Turkish consumers, gradual market expansion has occurred as urban middle-class consumers acquire a taste for it. While the emergence of health niche markets has been one factor, the interventions of multiple actors have also helped to create and sustain these markets that connect local producers to both local and global consumers.
Activation of Self-Incompatibility Signaling in TransgenicArabidopsis thalianaIs Independent of AP2-Based Clathrin-Mediated Endocytosis
Authors: Yamamoto Masaya , Nishio Takeshi , Nasrallah June B
Published: May 2018

Internalization of plasma membrane (PM)-localized ligand-activated receptor kinases and their trafficking to sorting endosomes have traditionally been viewed as functioning primarily in the down-regulation of receptor signaling, but are now considered to be also essential for signaling by some receptors. A major mechanism for internalization of PM proteins is clathrin-mediated endocytosis (CME). CME is mediated by the Adaptor Protein Complex 2 (AP2), which is involved in interaction of the AP2 μ-adaptin subunit with a tyrosine-based Yxxϕ motif located in the cytoplasmic domain of the cargo protein. In this study, we investigated the role of AP2-mediated CME for signaling by the S-locus receptor kinase (SRK), a protein localized in the PM of stigma epidermal cells, which, together with its pollen coat-localized S-locus cysteine-rich (SCR) ligand, functions in the self-incompatibility (SI) response of the Brassicaceae. Using Arabidopsis thaliana plants that were made self-incompatible by transformation with an A. lyrata-derived SRK/SCR gene pair, we tested the effect on SI of site-directed mutations in each of the two Yxxϕ motifs in SRK and of a CRISPR/Cas9-induced null mutation in the AP2 μ-adaptin gene AP2M. Both in vitro SRK kinase activity and the in planta SI response were abolished by substitution of tyrosine in one of the two Yxxϕ motifs, but were unaffected by elimination of either the second Yxxϕ motif or AP2M function. Thus, AP2-mediated CME is considered to be unnecessary for SRK signaling in the SI response.
Puntos de referencias biológicos para la ordenación pesquera de Ageneiosus pardalis (Auchenipteridae) en el embalse Urrá
Authors: Atencio García Victor , Salas Guzmán Fredy , Valderrama Barco Mauricio , Barreto Reyes Carlos
Published: May 2018

Se estimaron puntos de referencias biológicos de la doncella Ageneiosus pardalis en el embalse Urrá y ríos aportantes como mortalidad por pesca máxima (Fmax), mortalidad por pesca a 10 % (F0,1), mortalidad por pesca actual (F2015), mortalidad por pesca a máximo rendimiento económico (FMRE), máximo rendimiento económico (MRE) y máximo rendimiento sostenible (MRS). Además, se analizó la situación de la doncella bajo tres escenarios: 1) estado actual, 2) prohibición de pesca con mallas por dos meses (abril y noviembre) y 3) prohibición de pesca con malla por dos meses más el cumplimiento de la zona de reserva (colas Sinú y Verde). Las estimaciones de Fmax (1,1 año-1), F0,1 (0,6 año-1) y F2015 (1,2 año-1) sugieren que la especie está al límite de la sobrepesca. Para obtener un MRE ($130,6 millones de pesos), la FMRE debe ser de 0,6 año-1 y un MRS de 28,8 tm. En 2015, el 81 % de la doncella capturada estuvo por debajo de la talla mínima legal vigente (32 cm LE) y 51 % por debajo la talla de media de madurez estimada (26,6 cm LE). Los resultados del presente estudio permiten concluir que la población de doncella se encuentra en etapa inicial de sobrepesca y se recomienda la prohibición de la pesca con redes agalleras y la veda permanente en las colas del embalse con los ríos Sinú y Verde como el mejor escenario para esta especie.
Differential fruit choice in two simpatric monkey species and frugivorous bats in southern Mexico
Authors: Dzul Cauich Henry Fernando , Puc-Sosa Marili del Carmen , Canto-Osorio Juan Miguel , Ballina Gomez Horacio Salomón
Published: May 2018

Con el objetivo de examinar el papel que juegan las especies vegetales como fuentes alimenticias en la selección de frutos de agentes dispersores (Alouatta pigra, Ateles geoffroyi y murciélagos frugívoros), se realizó un estudio en selvas secas en el sureste de Yucatán, México. Se registraron los frutos consumidos por murciélagos usando colectores y, en el caso de los monos, se implementó el método de animal focal. El número de frutos consumidos registrados para ambas especies de primates y murciélagos fueron 342 y 386, respectivamente. Se determinó que los murciélagos depositaron frutos con pequeñas cantidades de pulpa, mientras que los monos contribuyeron mayormente con frutos totalmente despulpados (contrastes por pares LSD p < 0.05). Entre la variedad de especies de frutos en la dieta de los primates se detectó que A. pigra eligió frutos de las especies menos abundantes como Enterolobium cyclocarpum Jacq. Griseb. (1860) en vez de aquellas más abundantes (Manilkara zapota (L.) P. Royen (1953) y Brosimum alicastrum Sw. subsp. alicastrum C.C. Berg (1972)). El tipo de manejo de frutos y semillas causado por los primates sería más beneficioso para la germinación de las semillas que los aplicados por los murciélagos. Además, esta elección y manejo del fruto podría depender de sus características y la disponibilidad espacio-temporal de las especies de plantas como fuente de alimento.
Identificación de una colección de microalgas aisladas de Costa Rica mediante secuenciación de ADNr 18S
Authors: Gómez-Espinoza Olman , Guerrero-Barrantes Maritza , Meneses-Montero Karla , Núñez-Montero Kattia
Published: May 2018

Las microalgas componen un diverso grupo polifilético de microorganismos fotosintéticos.  Debido a su potencial biotecnológico, los estudios para aislar e identificar nuevas cepas han incrementado, por lo que es necesario el desarrollo de nuevas técnicas para su correcta identificación y clasificación. Utilizando herramientas de biología molecular, en este estudio se analizó el gen del ADNr 18S de 12 cepas microalgales aisladas de diferentes regiones de Costa Rica, resultando seis pertenecientes a la clase Trebouxiophyceae, tres a Chlorophyceae, dos a Prymnesiophyceae y una a Cyanidiophyceae. Este estudio reporta por primera vez la identificación molecular de cepas microalgales aisladas de Costa Rica, resaltando la diversidad de estos microorganismos en el país.
Direct stockpile scheduling: Mathematical formulation
Authors: Souza Felipe Ribeiro , Soares Chaves Leonardo , Burgarelli Hudson , Nader Alizeibek , Arroyo Carlos , Alberto Luiz
Published: May 2018

Según el contexto de industria minera la programación de producción es la mejor metodología para determinar la mejor secuencia de explotación y asi obtener el mejor valor presente líquido y explotar la reserva máxima. La construcción de pilas de acopio y de mezcla representa una alternativa valiosa para la planificación de minado permitiendo garantizar la calidad del concentrado y las especificaciones de la planta de tratamiento. Para satisfacer las especificaciones de leyes y tonelaje, y reducir las variaciones las pilas de acopio y mezcla cumplen un papel importante para la planificación de corto y largo plazo. La programación linear clásica viene siendo ampliamente utilizada en problemas de mezcla presentes en la industria minera entretanto esta formulación permite apenas trabajar con una sola función objetivo en su formulación. El presente trabajo describe un sistema basado en goal programing, capaz de alcanzar las restricciones requeridas en la planificación a corto y largo plazo de forma simultánea. La formulación propuesta obtiene el mejor escenario operacional garantizando que las restricciones de costos sean respetadas. Esta formulación es útil pues da soporte a la toma de decisiones en las actividades de planificación a largo y corto plazo.
Mobile learning on higher educational institutions: how to encourage it?. Simulation approach
Authors: Díez-Echavarría Luisa , Valencia Alejandro , Cadavid Lorena
Published: May 2018

Mobile learning es un proceso de aprendizaje basado en el uso de dispositivos móviles que permite adquirir conocimiento de manera interactiva y colaborativa. El objetivo de este artículo es comprender el fenómeno de la adopción del mobile learning entre estudiantes de educación superior, y evaluar políticas que pueden ser implementadas en instituciones, para favorecer la penetración de esta práctica. Desarrollamos un modelo de simulación basado en agentes que representan estudiantes, quienes deben decidir si asisten a una clase de manera presencial o virtual, a través de una regla de decisión basada en la Teoría del Comportamiento Planeado. Encontramos que las estrategias a corto plazo más eficaces son aquellas que favorecen la práctica del aprendizaje móvil durante fases de aprendizaje temprano, sin importar si es voluntaria o forzada. Asimismo, evidencian una naturaleza temporal de la adopción de esta práctica, entonces es necesaria la implementación de estrategias permanentes en el tiempo.