bluuebunny/crossref_metadata_2025 huggingface dataset:
Study the accumulation of minerals and heavy metals in Ulva algae, Cladophora, Polysiphonia and Laurencia algae samples at eastern north region of Libya coast
Authors: WESAM FA MOHAMED  , HAMAD M ADRESS HASAN
Published: June 2023

Different minerals including ( Na+, K+ and Ca++) in addition to ( iron and copper) were determined in different algae samples collected from some region at Al –Gabal Al –Khder coast region (Libya). The algae samples including (Ulva algae, Cladophora algae, Polysiphonia algae and Laurencia algae).The mineral contents were measured by Flamephotometer, while the (iron and copper) levels were estimated by spectrophotometeric method. The results showed variations between the contents of the studied algae samples. Where the results showed that the contents of sodium, calcium and potassium were fluctuated in the ranges of: (24 – 91 µg/ g) (4 – 13 µg/ g) and (3 – 16 µg/ g), respectively. While the contents of iron and copper were ranged between: (0.14 - 1.64 µg/ g) and (0.21 - 2.27 µg/ g), respectively.
Specificity of cellular communication, from signal to functional response
Authors: Bruno Riccardi
Published: June 2023

The specificity and complexity of molecular interaction is undoubtedly the characteristic trait shared by all universal matter. Quantum physics describes the nanometric particles that constitute it and the physically relevant properties that they express, by complex mathematical formulas, but it fails to identify the essence of the interactions that act within it. He also adopted a dedicated nomenclature for their description, but in no way manages to materialize them in an easily intelligible form. Even more difficult is trying to understand how communication between cells and living beings happens and how they can transfer a large variety of languages effectively. These communications use different identifiable codes within the same community even when issued simultaneously. The solution adopted to make such a complex system of interactions effective is the result of the millennial evolution and selection of an infinite number of molecules, each able to transmit with its characteristic steric imprint, a unique and unmistakable message. In this article we are going to describe how this mysterious communicative phenomenon takes place, even if we cannot grasp its intimate nature, which leaves us overwhelmed by so much complexity.
HUBUNGAN SIKAP DUDUK DAN LAMA DU PADA KARYAWAN CV. TUNAS MUDA TUBAN
Authors: Antariksa Rieke , Syarifah Has, S.KM., M.Epid Dwi Faqihatus
Published: June 2023

Nyeri punggung bawah merupakan  masalah musculoskeletal yang banyak dihadapi oleh pekerja saat melakukan pekerjaan, dan 90% kasus low back pain disebabkan oleh kesalahan posisi tubuh dalam bekerja. Tujuan penelitian ini untuk menganalisis hubungan sikap duduk dan lama duduk dengan kejadian low back pain pada karyawan CV. Tunas Muda Tuban.

Desain penelitian adalah analitic observasional dengan pendekatan cross sectional. Populasi adalah seluruh karyawan bagian menjahit CV. Tunas Muda Tuban sejumlah 50 orang. Jumlah sampel sebanyak 45 orang diambil dengan teknik random sampling. Variabel bebas penelitian ini adalah sikap duduk dan lama duduk karyawan, sedangkan variabel terikat yaitu kejadian low back pain. Instrumen yang digunakan penelitian ini adalah lembar kuesioner tentang sikap duduk berdasarkan pengukuran antropometri dan sarana kerja (meja dan kursi), lama duduk diukur berdasarkan Rapid Entire Body Assessment dan kejadian low back pain diukur oleh Oswestry Disability Index (ODI). Analisis menggunakan uji Chi-Square pada tingkat kepercayaan 95% (p<0,05).

Hasil menunjukkan bahwa sikap duduk sebagian besar tidak ergonomis, yaitu 60,0%, lama duduk sebagian besar durasi lama, yaitu 53,3%, dan kejadian low back pain sebagian besar low back pain, yaitu 55,6%. Ada hubungan sikap duduk dan lama duduk dengan kejadian low back pain pada karyawan CV. Tunas Muda Tuban dengan nilai p<0,05.

Melakukan gerakan peregangan sebelum dan setelah bekerja dengan posisi duduk yang lama serta memanfaatkan waktu istirahat yang cukup dapat mengurangi kejadian low back pain..
HUBUNGAN PENGGUNAAN SMARTPHONE DENGAN POLA TIDUR PADA ANAK KELAS IV DAN V DI SDN KRAMATJEGU 1 TAMAN SIDOARJO
Authors: Faridah Faridah
Published: June 2023

Smartphone usage in children if not controlled can have an impact on health, one of which is lack of sleep needs anathoer factor that can affect sleep is fatigue after physical activity such as traditional play. This study will identify of smartphone usage, traditional play activities, sleep patterns in children, analyze the relationship of using smartphone with sleep patterns and analyze the relationship traditional play activities and sleep patterns.The study used design observasional design with cross-sectional approach. The independent variable was the use of smartphone , traditional play activity and the dependent variable was sleep patterns. The sample were 54 children on smartphone use and 54 children on traditional play activities, used probability sampling technique with the Stratified random sampling approach. The instrument  on this study used questionnaire SAS , traditional play activities and PSQI, analyzed were by Spearman rho test. The results showed the level of smartphone usage is at most moderate (50.0%) and traditional play activities is at most highest (40.7%) with sleep patterns on smartphone use moderate (51.9%)  and with sleep patterns on traditional play activities good (44.4%). Spearman rho test showed there is no relationship between using smartphone with sleep patterns r= 0.572 (r≤a = 0.05) and there is no relationship between traditional play activities with sleep patternsr= 0.481 (r≤a = 0.05). Implications of the results showed the use of no smartphone usage don’t have relationship with sleep patterns in children and there is traditional play activities don’t have relationship with sleep patterns in children. This research is useful for parents in monitoring play activities carried out by children
HUBUNGAN BEBAN KERJA DENGAN KELELAHAN KERJA PADA GURU TAMAN KANAK-KANAK PIKPG GRESIK
Authors: Dwi Prihatini Shinta , Inayah, SKM., M.Kes Zufra
Published: June 2023

Profesi guru mempunyai tanggung jawab moral dan sosial pada peserta didik, wali murid dan masyarakat, sehingga beban kerja guru yang menyimpang dari ukuran ideal akan menyebabkan timbulnya kelelahan fisik. Tujuan penelitian ini untuk menganalisis hubungan beban kerja dengan kelelahan kerja pada guru Taman Kanak-Kanak PIKPG Gresik.

Desain penelitian adalah analitic observasional dengan pendekatan cross sectional. Populasi adalah seluruh guru TK PIKPG sejumlah 56 orang. Jumlah sampel sebanyak 50 guru diambil dengan teknik random sampling. Variabel bebas penelitian ini adalah beban kerja guru, sedangkan variabel terikat yaitu kelelahan kerja. Instrumen yang digunakan penelitian ini adalah lembar kuesioner tentang tugas pokok guru TK dan kuesioner Subjective Self Rating Test tentang pelemahan kegiatan, pelemahan motivasi kerja dan gambaran kelelahan fisik. Analisis menggunakan uji Kendall Tau pada tingkat kepercayaan 95% (p<0,05).

Hasil menunjukkan bahwa beban kerja guru hampir seluruhnya atau 84% kategori berat, dan kelelahan kerja guru hampir setengahnya atau 42% kategori tinggi. Ada hubungan beban kerja dengan kelelahan kerja pada guru Taman Kanak-Kanak PIKPG Gresik dengan nilai korelasi 0,353 dan p = 0,005 (p<0,05).

Diperlukan pengendalian kelelahan kerja dengan cara penempatan pekerjaan sesuai dengan umur dan pengalamannya serta kemampuan secara fisik
K-MEANS CLUSTER COUNT OPTIMIZATION WITH SILHOUETTE INDEX VALIDATION AND DAVIES BOULDIN INDEX (CASE STUDY: COVERAGE OF PREGNANT WOMEN, CHILDBIRTH, AND POSTPARTUM HEALTH SERVICES IN INDONESIA IN 2020)
Authors: Utami Iut Tri , Suryaningrum Fahlevi , Ispriyanti Dwi
Published: June 2023

One of the causes of the increasing maternal mortality rate in Indonesia is the declining performance of maternal health services in each Indonesian province. To overcome the decline in performance, namely by determining in advance the provinces that need to be prioritized for services by grouping 34 provinces in Indonesia. This study aims to obtain the best provincial grouping results so that it can prioritize the right provinces. One of the methods that are suitable for grouping provinces is K-Means because it is simple and easy to implement. The disadvantage of K-Means is that it is sensitive to determining the right number of initial clusters, so Silhouette Index and Davies Bouldin Index validation is used to obtain the optimal number of clusters with stable and consistent results. This study used healthcare data for pregnant women, childbirth, and postpartum with K=2, 3, and 4 as the initial cluster number. K-Means objects are grouped in similarities using Euclidean and Manhattan distances. The result obtained was the optimal number of clusters with K=2 using Manhattan, where the highest Silhouette Index value was 0,658685 and the lowest Davies Bouldin Index was 0,3561214 which met the criteria for determining the optimal cluster.
TSUKAMOTO FUZZY IN OPTIMIZING THE CREDITWORTHINESS ASSESSMENT PROCESS AT SAVINGS AND LOAN COOPERATIVES
Authors: Setiawan Tabah Heri , Prihatini Laras
Published: June 2023

Savings and Loan Cooperatives are ones of the non-bank institutions whose business activity is the provision of loan. In its business activities, problems often arise, namely non-performing loans which causes no turnover of funds which leads to losses. One of the causes of non-performing loans is the lack of objective creditworthiness assessment. The purpose of this study is to optimize the process of assessing the feasibility of loan applications at Savings and loan credit with assessment criteria: loan value, total income, loan term and collateral value. The tsukamoto fuzzy method was used in this study. Tsukamoto fuzzy method consists of four steps.: fuzzification, Forming fuzzy rules, application of implication functions using the MIN function and defuzzification using the weighted average calculation method. In this research, it was found that Tsukamoto's fuzzy method can be applied to the creditworthiness assessment process at the Saving and Credit Cooperatives. This is because the accuracy rate of the decision results from the tsukamoto method is 93.75%. A total of 60 data out of 64 data are in accordance with the eligibility decision at one of Saving and loan Cooperatives in West Java, Indonesia. Tsukamoto fuzzy method can optimize the credit assessment process in Savings and loan Cooperatives because the eligibility assessment process becomes more efficient and objective.
SELECTION OF THE BEST SEM MODEL TO IDENTIFY FACTORS AFFECTING MARKETING PERFORMANCE IN THE ICT INDUSTRY
Authors: Hikmah Zetil , Wijayanto Hari , Aidi Muhammad Nur
Published: June 2023

The digital revolution in society and the advances in marketing practices create tremendous challenges for companies and even more so for Information and Communication Technology (ICT) service providers. They are faced with increasingly complex and rapidly changing market competition, knowing these problems can use SEM to form a research model and find out the relationship between latent variables and their indicators. The purpose of this study is to identify the best structural equation model that can describe Marketing Performance in the ICT Industry in Indonesia. The data used in this study is primary data obtained from the results of distributing offline and online questionnaires to 300 management levels working in the ICT Industry. The methods compared in this study are Covariance Based Structural Equation Modeling and Partial Least Square Structural Equation Modeling. The results showed that the best model to determine the factors that influence Marketing Performance in the ICT Industry in Indonesia is PLS-SEM with the goodness-of-fit model R2 for the latent variable Marketing Performance is 0.436. This shows that the accuracy of the variables CEM, DBI and DOE together in predicting MP variables is relatively weak. Based on the PLS-SEM model, it is found that Digital Operational Excellence is a mediator that can increase the influence of Customer Experience Management on Marketing Performance. Meanwhile, Digital Business Innovation has no significant effect in increasing the influence of Customer Experience Management on Marketing Performance. The novelty of this research is the development of the best SEM models (CB-SEM and PLS-SEM) in the field of Information and Communication Technology in Indonesia.
HIERARCHICAL CLUSTER ANALYSIS ON PEOPLE'S WELFARE IN SOUTHEAST SULAWESI PROVINCE
Authors: Musa Marsuddin , Fallo Sefri Imanuel
Published: June 2023

Problems with people's welfare typically result from the government's development efforts in a region not being done properly or not being done equally. Consider grouping and defining the traits of each region's degree of welfare as a potential answer to ensure that development policies and strategies are well-targeted. This study aims to classify 17 regency/cities in Southeast Sulawesi province based on several indicators of people's welfare. The method used is hierarchical cluster analysis with several approaches, including Single Linkage, Complete Linkage, Average Linkage, and Ward's. The data used in this study is secondary data obtained from the publication of the Central Agency of Statistics (CAS) of Southeast Sulawesi Province. Based on the results of the evaluation the best method used is Ward's method which produces three clusters. The first cluster consists of 9 regencies, namely Buton, North Buton, South Buton, Central Buton, Muna, West Muna, Wakatobi, Konawe Islands, and East Kolaka, the majority of which come from the archipelago. Some of the problems that occur in these areas are the relatively high poverty rate and the low average length of schooling and life expectancy. The same thing happened to the second cluster which consisted of 6 regencies, namely Konawe, South Konawe, North Konawe, Bombana, Kolaka, and North Kolaka with problems of poverty, the average length of schooling, and relatively low sources of proper drinking water when compared to other clusters. The third cluster consists of 2 urban areas, namely Kendari City and Baubau City, the problems that occur are the relatively high unemployment rate and population density. The government ought to offer more initiatives to handle issues with poverty, education, and health in regions in clusters 1 and 2. While in cluster 3, the government ought to offer more initiatives to combat jobless issues and prepare for rising population densities.
FINANCIAL INCLUSION, ECONOMIC GROWTH AND POVERTY IN INDONESIA WITH PANEL SIMULTANEOUS MODELS APPROACH
Authors: Almasah Munifah Zuhra , Sirait Timbang
Published: June 2023

Financial inclusion is a condition that people have equal access to and use financial services. However, in 2021, Indonesia will have the fourth-highest proportion of unbanked citizens worldwide. Economic growth may have an indirect or direct impact on poverty depending on financial inclusion. Several variables that encourage financial inclusion have been described by many studies. This study aims to analyze simultaneous equation models using panel data of financial inclusion, then identify its causality relationship with economic growth and poverty of 33 provinces in Indonesia from 2011-2021. As result, only the variable mean years of school has an effect on increasing of financial inclusion index. The three variables of economic development, namely financial inclusion, economic growth, and poverty have a one-way causality relationship. That is means there has been no visible development synergy in terms of financial inclusion, economic growth, and poverty. It could be an example given to the government in evaluating Indonesia's regional development gap.
FORECASTING THE CONSUMER PRICE INDEX WITH GENERALIZED SPACE-TIME AUTOREGRESSIVE SEEMINGLY UNRELATED REGRESSION (GSTAR-SUR): COMPROMISE REGION AND TIME
Authors: Arum Prizka Rismawati , Indriani Anita Retno , Haris M Al
Published: June 2023

Economic success will provide benefits for improving people’s welfare. An important indicator to determine economic success can be seen through inflation by calculating the Consumer Price Index (CPI). CPI is a time series data that is influenced by elements between locations. The GeneralizedSpace-Time Autoregressive (GSTAR) method is a suitable method to be applied to CPI data because it involves elements of time and location (spatiotemporal). The problem is that the GSTAR model cannot detect any correlated residuals. The GSTAR model was developed into the GSTAR-SUR model to estimate parameters with correlated residuals so produce more efficient estimates. The purpose of this study was to determine the best GSTAR-SUR model to predict the CPI of six cities in Central Java, namely Cilacap, Purwokerto, Kudus, Surakarta, Semarang, and Tegal. The data that used is secondary data sourced from BPS Central Java Province. Based on the results of the analysis, the best model formed is the GSTAR-SUR (11)-I(1) model with an RMSE value of 6.213. Forecasting results show that the CPI value for the next 6 months will increase every month for each city
Empaattinen reflektivismi Hannele Huovin nuortenromaaneissa
Authors: Rättyä Kaisu
Published: June 2023

Nuortenromaanien ydintä on identiteetin etsintä ja aikuisuuteen astuminen. Hannele Huovi rakentaa teoksiinsa reflektoivia peilejä ja pintoja, jotka auttavat henkilöhahmoja pohtimaan identiteettiään. Huovin Madonna (1986), Vladimirin kirja (1988), Tuliraja (1994) ja Lasiaurinko (1996) uudistivat 1980- ja 1990-luvun ongelmarealistista nuortenromaania teemojen, muotojen ja lajikonventioiden luovalla yhdistelmillä ja rakensivat samalla empaattista lähestymistapaa nuorten elämän kuvaukseen idyllittömyyden tilalle. Huovin nuortenromaanit esittelen reflektivismi-määreen alla, jolla viittaan teoksissa esiintyvään temaattiseen ja rakenteelliseen reflektointiin, joka tukee päähenkilöiden identiteetin etsimisen prosessia ja sen esittämistä.
Suomalaisen tunteiden poetiikan ja retoriikan tutkimuksen inspiroimana tarkastelen Hannele Huovin neljän nuortenromaanin rakenteita empatian näkökulmasta. Lähtökohtanani Suzanne Keenin kerronnallisen empatian teoria selvitän, kuinka kohdeteosten kerronnalliset, refleksiivisyyttä korostavat rakenteet luovat empatiaa. Pohdin kerronnallisia heijastuspintoja luovien rakenteiden merkitystä empatian mahdollistajina kerronnan tasojen näkökulmasta, upotusten, sisäkertomusten ja kynnystekstien näkökulmasta sekä metanarratiivisuuden näkökulmasta.
Huovin nuortenromaanien kerronnan tarkastelu kerronnallisen empatian teorian ja siihen liitettyjen kerronnan keinojen avulla osoitti, millainen tekstien ja kertomusten merkitys on nuorten elämässä ja eettisten kysymysten pohdinnassa. Teokset avaavat päähenkilöiden tunteita lukijalle niin realistisen tilannekuvausten kuin kertomisen, kirjoittamisen ja sisäkertomustenkin avulla. Henkilöhahmojen tunteiden tunnistamisen ja samaistumisen mahdollistuu hyvin, kun empatiapositioita on runsaasti. Huovin teosten laadun määritän empaattinen reflektivismi -termillä. Empaattisessa reflektivismissä päähenkilöt reflektoivat identiteetinetsintäänsä, heidän toimensa ja puheensa kuvastavat etsintää, samalla kun myös teoksen kerronnalliset rakenteet peilaavat identiteetin etsintää tarjoavat lukijalle empatiapositioita esimerkiksi sisäkertomusten henkilöhahmojen tai ekfrasisten avulla.
The importance of the genital tract microflora in the endometriosis development
Authors: Pakharenko L.V. , Basiuha I.O. , Zhurakivskyi V.M. , Lasytchuk O.M. , Kurtash N.Yа.
Published: June 2023

Endometriosis is a common pathology among women of reproductive age. In the pathogenesis of its development a great importance is paid to the process of regulation of estrogens and other sex hormones, the implementation of the immune response at the general and local levels, the inflammatory response, and genetic background. In recent years, the role of the microbiota in different parts of the genital tract of the female organism has been studied not only from the standard approach of inflammatory diseases research of the reproductive organs and pathological vaginal discharge, but its contribution into the development of other gynecological diseases, in particular endometriosis, is presented.The article is devoted to a review of scientific publications about researches devoted to the significance of the genital tract microflora in the pathophysiology of endometriosis. The article presents the concepts of states of eubiosis and dysbiosis, describes the features of the microflora of the lower (vagina, cervix) and upper parts (uterus, fallopian tubes) of the genital tract in healthy women. The data on the importance of Lactobacillus in maintaining an optimal state of acidity in the vaginal environment are presented. The difference in the composition of the microbiota of the vagina, cervical mucus, uterine cavity and peritoneal fluid in women with and without endometriosis is revealed. The pathogenetic mechanisms of the role of the microbiota in the processes of endometriosis pathogenesis, namely, the regulation of the immune response and inflammation processes in this pathology, are described. It has been shown that in women with endometriosis there are differences in the microflora composition of the vagina, cervix, uterine cavity, peritoneal fluid, manifested by a decreased concentration of Lactobacillus and the presence of a variety of other microorganisms in relation to healthy women. The data about the role of gut microflora in patients with this pathology are also presented. The results of research about the diagnosis of various stages of endometriosis by studying the composition of the genital tract microbiota are described.
Цитотоксическая активность ряда A-модифицированных производных тритерпеноидов солодки
Authors: Балтина Лидия Ашрафовна , Хуснутдинова Наиля Сабитовна , Каримова Эльза Рамилевна , Сайфуллина Дина Ринатовна , Кондратенко Римма Минибаевна
Published: June 2023

Изучена цитотоксическая активность ряда A-модифицированных производных глицирретовой кислоты (ГЛК), 11-дезоксо- и 18,19-дегидро-ГЛК в отношении условно-нормальных клеток HEK293, карциномы легкого человека А549, аденокарциномы молочной железы MCF-7 и нейробластомы SH-SY5Y. Наиболее активным соединением оказался метиловый эфир 18,19-дегидро-ГЛК с пиразольным фрагментом, который показал выраженное цитотоксическое действие в отношении раковых клеточных линий А549, MCF-7 и SH-SY5Y (IC50 22,57 – 38,11 мкМ).
Исследование сорбции некоторых биологически активных соединений растительного происхождения на металлоорганических каркасных полимерах
Authors: Шайхутдинов Ильнур Хясяинович , Рязанова Татьяна Константиновна , Соколова Ирина Владимировна , Куркин Владимир Александрович , Соколов Андрей Владимирович
Published: June 2023

Представлены результаты скрининговых исследований по оценке сорбции ароматических биологически активных соединений природного происхождения, представленных фенолкарбоновыми кислотами, кумаринами, флавоноидами и алкалоидами, на алюминий- и железосодержащих металлоорганических каркасных полимерах (МОКП). Для подтверждения структуры синтезированных МОКП использовали методы рентгеновской дифрактометрии, порозиметрии, ИК-НПВО (нарушенного полного внутреннего отражения) спектроскопии. Методом УФ-спектрофотометрии проведен количественный анализ сорбции аналитов. Определено, что сорбционная активность железосодержащих МОКП выше сорбционной активности алюминийсодержащих МОКП. Различие в значениях сорбционной емкости указывает на возможности направленного подбора МОКП для селективного удержания или разделения смеси веществ разной химической природы.
Компонентный состав липидсодержащих отходов переработки надземных частей Ferula tenuisecta, Ferula kuhistanica и создание масляной композиции ранозаживляющего действия
Authors: Халилов Равшанжон Муратджанович , Маматханова Мунирахон Умарханович , Асилбекова Дания Толимбековна , Бобакулов Хайрулла Мамадиевич , Юсупова Севар Муминовна , Эгамова Феруза Рустамовна , Маматханов Ахматхон Умарханович
Published: June 2023

Исследованы отходы (экстракты, полученные при обработке сгущенного водно-спиртового экстракта экстракционным бензином) переработки надземных частей ферулы тонкорассеченной (Ferula tenuisecta Korov. ex Pavlov) и ферулы кухистанской (Ferula kuhistanica Eug. Kor.). Выявлено, что отходы содержат нейтральные липиды с высоким содержанием ненасыщенных жирных кислот (F. tenuisecta — 58,4 %, F. kuhistanica — 63,1 %). Установлено, что главными жирными кислотами отходов являются линоленовая, линолевая и олеиновая кислоты, а мажорными — пальмитиновая кислота и её гомологи ряда С10 – С22. Фармакологические исследования показали, что масляная композиция, приготовленная на основе липидов и липофильных веществ из отходов переработки надземной части F. kuhistanica, оказывает выраженное положительное влияние на процесс заживления плоскостных полнослойных кожных ран у мышей (уменьшение воспалительного отёка, усиление контракции с последующим ускоренным заполнением ран грануляционной тканью и их эпителизацией) и резаных линейных ран у крыс (усиление регенераторных процессов в области раны и существенное повышение прочности образовавшегося рубца).
Innocents Abroad? The Consumption of Antiquities from the Holy Land
Authors: Kersel Morag M.
Published: June 2023

Why do people want to own a piece of the past? What tempts consumers? What effect does consumption have on archaeological landscapes? Generally, Holy Land consumers can be broken down into two categories: those on the low-end interested in small mementoes of a trip, and those on the high-end, wealthier individuals willing to make financial investments for the highest quality pieces. Whether buyers are wily speculators, investing to increase their capital (cultural, economic, social, sensu Bourdieu), or innocent pilgrims on a once in a lifetime trip to the Holy Land, the result is the same: looting and theft from archaeological sites in order to meet consumer demand for archaeological artifacts. With data gathered from archaeological ethnographies, this article assesses the purchasers of artifacts, the unintended consequences of their acquisitions, and considers the ways we might create a set of better-informed consumers in the licensed antiquities market in Israel.
POTENCIAL TERAPÊUTICO DA VITAMINA D EM PACIENTES COM DOENÇA RENAL CRÔNICA: REVISÃO SISTEMÁTICA
Authors: Juciele da  Rocha Marcia , Mroginski  Weber Douglas , Carvalho Nogueira Amanda , De Matos Teixeira Anna Felícia , Moreira Dias Costa Borges Bárbara , Da Silva Bezerra Fernanda , Da Silva Lima Flávia
Published: June 2023

Objetivo: avaliar o potencial terapêutico da vitamina D e seus análogos em paciente com DRC. Método: Trata-se de uma revisão sistemática, conforme os passos propostos pela metodologia Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Foram usadas as bases de dados SciELO, Medline, PubMed e LILACS para o levantamento dos artigos. A qualidade metodológica das investigações foi realizada por meio do método de Jadad e Newcastle-Ottawa (NOS). Resultados: Foram identificados 132 artigos iniciais, dos quais 5 foram selecionados para revisão atendendo a todos os critérios de elegibilidade. Os resultados indicaram que o uso da vitamina D como terapia medicamentosa em pacientes com DRC contribuiu para melhorar a função endotelial dos vasos através da diminuição da rigidez vascular, apresentou ação protetora contra infecções através de imunomodulação, diminuição do paratormônio (PTH) e estabilização da taxa de filtração glomerular (TFG). Considerações Finais: Nesse sentido, pode-se concluir que a vitamina D torna-se um agente terapêutico para múltiplos tecidos contribuindo na qualidade de vida dos pacientes com DRC.
Effects of an “Internet +” Multidisciplinary Management Model Oriented by Nurse Specialists on Obesity Combined with Polycystic Ovary Syndrome
Authors: Ou Yuyi , Wu Lixia , Liu Li , Ye Xiutao , Chen Yanjin , Yuan Huizhi
Published: June 2023

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine metabolic disease in women of reproductive age, and its treatment mainly relies on adjusting lifestyle and oral drug therapy. With the development of the Internet and shared economy, the “Internet + nursing services” model has become increasingly popular, is presently an essential component of the Health Wellness project and has a promising future. Methods: This study involved 100 gynecological outpatients with PCOS from the Foshan Maternal and Child Health Hospital. They were divided into a control (routine nursing) and an experimental (“Internet +” multidisciplinary management oriented by nurse specialists) group according to a predefined nursing scheme. Several indicators, such as rates of ovulation and pregnancy, body mass index (BMI), waistline, serum hormone levels, metabolic indicators and psychological status of patients, were compared between the two groups before and half a year after the nursing intervention. Results: Six months after the intervention, the experimental group had significantly higher ovulation and pregnancy rates than the control group (88.00% vs. 68.00%, 48.00% vs. 22.00%, p < 0.05). Additionally, the experimental group showed a significant decrease in BMI, waistline, serum hormone levels (i.e., testosterone and luteinizing hormone [LH]) and homeostasis model assessment of insulin resistance (HOMA-IR) compared to the control group (p < 0.05). However, no obvious differences were observed in follicle-stimulating hormone (FSH) and fasting blood glucose (FBG) (p > 0.05) compared with the control group. Further, patients in the experimental group also displayed better psychological status, with a significant decrease in self-rating anxiety scale (SAS) scores and self-rating depression scale (SDS) half a year after intervention (p < 0.05). Conclusions: Interventions using the “Internet +” multidisciplinary management model oriented by nurse specialists not only effectively increased the rates of ovulation and pregnancy of PCOS patients but also significantly improved patients’ indicators such as BMI, waistline, serum hormone levels, metabolic indicators, and psychological status.
Audiological Diagnosis of Valvular and Congenital Heart Diseases in the Era of Artificial Intelligence
Authors: Ainiwaer Aikeliyaer , Kadier Kaisaierjiang , Qin Lian , Rehemuding Rena , Ma Xiang , Ma Yi-Tong
Published: June 2023

In recent years, electronic stethoscopes have been combined with artificial intelligence (AI) technology to digitally acquire heart sounds, intelligently identify valvular disease and congenital heart disease, and improve the accuracy of heart disease diagnosis. The research on AI-based intelligent stethoscopy technology mainly focuses on AI algorithms, and the commonly used methods are end-to-end deep learning algorithms and machine learning algorithms based on feature extraction, and the hot spot for future research is to establish a large standardized heart sound database and unify these algorithms for external validation; in addition, different electronic stethoscopes should also be extensively compared so that the algorithms can be compatible with different. In addition, there should be extensive comparison of different electronic stethoscopes so that the algorithms can be compatible with heart sounds collected by different stethoscopes; especially importantly, the deployment of algorithms in the cloud is a major trend in the future development of artificial intelligence. Finally, the research of artificial intelligence based on heart sounds is still in the preliminary stage, although there is great progress in identifying valve disease and congenital heart disease, they are all in the research of algorithm for disease diagnosis, and there is little research on disease severity, remote monitoring, prognosis, etc., which will be a hot spot for future research.
Dark Matter and Dark Energy
Authors: Kavak Mesut
Published: June 2023

I have been working on the fundamental laws of physics for a long time. During this time, I realized that gravity does not work like Newtonian and this misleads us into Dark Matter. The relationship between distance and gravitational force varies with distance. The gravity equation varies with some value between $1/r$, $1/r^2$ or $1/r^4$ for the farthest or closest available distance. However, empty space also has a gravitational and expansion effect. This study aims to analyze and discuss these two phenomena. This work explains observational galaxy rotation curves without dark matter.
PENGARUH KESADARAN HALAL LABEL HALAL DAN BAHAN MAKANAN TERHADAP MINAT BELI KONSUMEN
Authors: Marina Riina , Nurmelinda Elma , Fikriy Muhammad Nazib , Abadia Hanisa'adatul , anggun fenny , Nurhidayatun  , Faisal Agus , Hafifah Sri , Wandani Novita Tries
Published: June 2023

This study aims to determine the effect of halal certification, halal awareness, and food ingredients on the intention to buy halal food products among students. This study used a quantitative approach, the data sources used were primary data and secondary data, the population used in this study were Muslim students. The sampling technique of this study took as many as 58 respondents. The data analysis technique used is descriptive analysis, statistical analysis is in the form of multiple linear regression tests, where all the testing processes use a tool in the form of SPSS. The results of this study show that partially the social environment and motivation have a positive and significant effect on the influence of halal awareness, halal labels and food ingredients on the intention to buy culinary food among students, simultaneously there is a positive and significant effect between the variables halal awareness, halal labels and food ingredients on interest in buying culinary food by (%)
UAS ILMU POLITIK DAN PENDIDIKAN IPS
Authors: Hasrianah
Published: June 2023

Mengapa kekuasaan diperlukan untuk mempengaruhi kebijakan politik. Uraikan bagaimana pendapat Anda.Jawaban: Kekuasaan dan politik merupakan satu kesatuan yang tidak dapat dipisahkan. Dimana politikmerupakan bentuk untuk memperoleh kekuasaan, “bagaimana memperoleh kekuasaan”. Ketikakita berbicara tentang politik, sebenarnya kita berbicara tentang strategi untuk mendapatkankekuasaan. Kekuasaan adalah energi yang dimiliki seseorang atau kelompok untuk mencapaitujuan yang ingin dicapai. Kekuasaan dalam politik berarti menghimpun dan menginvestasikanenergi setiap kelompok untuk memperoleh kekuatan guna menyeimbangkan dan mencapaitujuan yang ingin dicapai. Orang atau kelompok lain. Karena berbagai alasan, ideologi tidaksesuai dengan dogma budaya atau agama. Kekuasaan yang diperoleh dengan politik merupakanupaya untuk mengontrol secara ideologis masyarakat umum (mahasiswa) agar yang berkuasaberada pada level tertinggi, atau sering disebut sebagai “elit”. Elit, sebagai minoritas, adalahkelompok mayoritas yang berkuasa, sehingga semua jenis perilaku dalam masyarakat seringkali dipandang sebagai perilaku yang seragam Konsekuensinya, dari sudut pandang politik, munculdalam bentuk pernyataan, yang kemudian diekspos sebagai kebijakan masyarakat umumKebijakan elite mengatur tingkah laku semua manusia dalam mewujudkan dan memajukankehidupan, baik dalam pemerintahan bermasyarakat maupun dalam kehidupan bermasyarakat.
Social Transformation in the Digital Age: Implications and Challenges for Sociology
Authors: azzmi kariematul
Published: June 2023

Social change in the digital era has a significant impact on society, affecting social interaction, work, education and culture. This transformation also raises social challenges and conflicts that need to be overcome. In this context, sociology plays an important role in understanding and formulating sustainable measures. Through its critical and analytical approach, sociology analyzes the impact of these changes on individuals and society. Sociology pays attention to social implications, social and economic inequality, as well as issues of privacy and data security in a digital context. In addition, sociology plays a role in formulating inclusive policies and practices as well as developing digital literacy and critical understanding of digital media.
UAS ILMU POLITIK DAN PENDIDIKAN IPS
Authors: Kamila Maya
Published: June 2023

Kekuasaan adalah kemampuan yang harus sangat dimiliki untuk mempengaruhi seseorang atau kelompok lain untuk mendapatkan kewenangan, merebut dan mempertahankan kekuasaan yang memiliki tujuan untuk kepentingan seluruh golongan masyarakat. Menurut saya kekuasaan itu perlu untuk kebijakan politik karena Kekuasaan dan politik itu adalah satu kesatuan yang tidak dapat dipisahkan. Ketika kita membicarakan politik maka sebenarnya kita membicarakan suatu strategi bagaimana mendapatkan atau mempertahankan kekuasaan. Lalu dengan adanya kekuasaan maka seseorang itu dapat mendiskusikan, memerintah maupun melakukan sesuatu untuk membuat kebijakan tersebut. Tanpa adanya kekuasaan segala kebijakan yang berasal dari perintah tidak akan terlaksana.
UAS Ilmu Politik dan Pendidikan IPS Muhammad Rifky 2210128210008
Authors: Muhammad Rifky
Published: June 2023

1. Mengapa kekuasaan diperlukan untuk mempengaruhi kebijakan politik. Uraikan bagaimana pendapat Anda. 2. Jelaskan menurut pandangan anda tentang perkembangan Dinamika Demokrasi yang ada di Indonesia. 3. Uraikan bagaimana hubungan antara politik dengan pendidikan. 4. SIlakan pilih 1 tulisan di google scholar MZA Anis Anis dan Muhammad Adhitya Hidayat Putra (masing-masing 1), kemudian kutip dan korelasikan dengan materi politik disertakan contoh konkrit! 5. Sebutkan dan Jelaskan sejarah etika protestan menurut anda dan sertakan sumber.
THE ROLE OF ENVIRONMENTAL SOCIALUZATION IN FORMING COMMUNITY VALUES
Authors: Hidayat M. Rifki
Published: June 2023

In this research, it aims to understand the role of environmental socialization in shaping community values and the main problem that is examined is how the influence of environmental socialization on the formation of values held by individuals and society in general. The aim of this research is to identify factors -Factors influencing the process of environmental socialization and evaluating its impact on social values formed in the research method used is a qualitative approach by conducting in-depth interviews and participatory observations of a number of respondents who come from various social and cultural backgrounds. Data collection is carried out through direct interaction with respondents, as well as an analysis of the social and environmental context that influences the formation of values and research results show that environmental socialization plays an important role in shaping community values such as the physical environment, such as housing, infrastructure, and access towards natural resources, in influencing the way individuals and communities view and appreciate the environment, besides that it also has a significant influence in shaping social values related to the role of environmental socialization in shaping societal values in this study also shows that education and the media The masses play an important role in the process of environmental socialization in schools and educational institutions to help transmit knowledge and values about the importance of protecting the environment to the younger generation, while the mass media also has the power to shape people's perceptions and attitudes towards environmental issues concerning the role of socialization. values that shape society so that it is better and active in terms of values and morals from the social context that this research method is to form good social towards the community environment and values towards society.
Transforming Social Norms in Pekalongan: How Electric Vehicles are Changing Social Perceptions
Authors: Aziz Nabil Abdul
Published: June 2023

The revolutionary shift towards electric vehicles (EVs) and the transition from fossil fuels in Indonesia's transportation sector. The adoption of EVs as a sustainable alternative to conventional fossil fuel-powered vehicles represents a transformative paradigm with significant social, environmental, and economic implications. Indonesia, as a developing country experiencing rapid population growth and urbanization, faces pressing transportation issues such as air pollution, traffic congestion, and dependence on imported fossil fuels. The introduction of EVs offers an attractive opportunity to address these challenges while driving toward a cleaner and greener future. The primary objective of this research is to explore the potential benefits of transitioning to EVs in Indonesia. The research methodology utilized in this study includes observation and interviews to gain a better understanding of the shift to EVs and the transition from fossil fuels to Indonesia. This approach enables researchers to collect relevant data, directly observe on-the-ground situations, and obtain insights and perspectives from various stakeholders involved. The research findings highlight several key points. Firstly, the transition to EVs can significantly reduce greenhouse gas emissions, making a substantial contribution to Indonesia's climate change mitigation efforts. Secondly, improved air quality resulting from reduced pollution levels can have positive impacts on public health, reducing respiratory diseases and related healthcare costs. Lastly, the widespread adoption of EVs necessitates the development of adequate infrastructure, and EV prices in Indonesia are still relatively high due to the newness of the technology.
Cognitive-Behavioral Treatment for Gambling Harm: Umbrella Review and Meta-Analysis
Authors: Pfund Rory A , Ginley Meredith K. , Kim Hyoun Soo , Boness Cassandra L. , Horn Tori , Whelan James P.
Published: June 2023

The aim of the current umbrella review and meta-analysis was to evaluate the methodological rigor of existing meta-analyses on cognitive-behavioral treatment (CBT) for gambling harm. The Cochrane Database of Systematic Reviews, PsycINFO, and PubMed were searched for meta-analyses of CBT for gambling harm among individuals aged 18 years and older. The search yielded five meta-analyses that met inclusion criteria, representing 56 unique studies and 5,389 participants. The methodological rigor for one meta-analyses was rated high, two were moderate, and two were critically low. Including only moderate- to high-quality meta-analyses, a robust variance estimation meta-analysis indicated that CBT significantly reduced gambling disorder severity (g = -0.91), gambling frequency (g = -0.52), and gambling intensity (g = -0.32) relative to minimal and no treatment control at posttreatment, suggesting 65%-82% of participants receiving CBT will show greater reductions in these outcomes than minimal or no treatment controls. Overall, there is strong evidence for CBT in reducing gambling harm and gambling behavior, and this evidence provides individuals, clinicians, managed care companies, and policymakers with clear recommendations about treatment selection.
UAS POLITIK - SANDY PRADIPTA NALAPRAYA
Authors: Nalapraya Sandy Pradipta
Published: June 2023

1.Mengapa kekuasaan diperlukan untuk mempengaruhi kebijakan politik. Uraikan bagaimana pendapat Anda. 2.Jelaskan menurut pandangan anda tentang perkembangan Dinamika Demokrasi yang ada di Indonesia. 3.Uraikan bagaimana hubungan antara politik dengan pendidikan. 4.SIlakan pilih 1 tulisan di google scholar MZA Anis Anis dan Muhammad Adhitya Hidayat Putra (masing-masing 1), kemudian kutip dan korelasikan dengan materi politik disertakan contoh konkrit! 5.Sebutkan dan Jelaskan sejarah etika protestan menurut anda dan sertakan sumber.
UAS POLITIK DAN PENDIDIKAN IPS HAYATUN NISA 2210128120003 A-1
Authors: NISA HAYATUN
Published: June 2023

uas Politik Education
UAS Ilmu Politik dan Pendidikan IPS
Authors: Rohima Najwa
Published: June 2023

Definisi dari kekuasaan ialah kemampuan untuk mengendalikan tingkah laku orang secara langsung (perintah) atau tidak langsung (melakukan segala hal dengan alat/cara). Sedangkan politik sendiri ialah sebuah upaya untuk berperan dalam mengendalikan serta mengurus urusan warga negara.
Testing for Group Differences in Multilevel Vector Autoregressive Models
Authors: Haslbeck Jonas M B , Epskamp Sacha , Waldorp Lourens
Published: June 2023

Multilevel Vector Autoregressive (VAR) models have become a popular tool for analyzing time series data from multiple subjects. Many studies aim to investigate differences in multilevel VAR models between groups, such as patients and healthy controls. However, there is currently no easily applicable method to make inferences about such group differences. Here, we present two standard tests for making such inferences: a parametric test and a nonparametric permutation test. We explain the rationale for both tests, provide an implementation based on the popular R-package mlVAR, and evaluate their performance in recovering group differences in scenarios resembling empirical research using a simulation study. Finally, we provide a fully reproducible R-tutorial on testing for group differences in a dataset of emotion measures using the new R-package mnet.
Iconic Artificial Language Learning: A Conceptual Replication with English Speakers
Authors: Shapiro Naomi Tachikawa , Steinert-Threlkeld Shane
Published: June 2023

We introduce an iconic approach to artificial language learning, one that replaces traditional phonologically-grounded stimuli with pictographic writing systems. Conducting an experiment with English speakers, we demonstrate the viability of this approach by reproducing word order effects observed in multiple studies (e.g., Culbertson & Adger, 2014; Martin, Holtz, Abels, Adger, & Culbertson, 2020). Importantly, iconic artificial languages make it possible to re-use the same linguistic stimuli with diverse language populations, facilitating crosslinguistic investigations.
Increased anticholinergic medication use in middle aged and older autistic adults and its associations with self-reported memory difficulties and cognitive decline
Authors: McQuaid Goldie , Duane Sean , Ahmed Neha , Lee Nancy Raitano , Charlton Rebecca Ann , Wallace Gregory
Published: June 2023

Many commonly used prescription and over-the-counter medicines have potent anticholinergic (AC) effects. Among older adults, AC medications are associated with cognitive impairment, and risk for cognitive disorders, including Alzheimer’s Disease. Collectively, the impact of AC medications is known as anticholinergic cognitive burden (ACB). Because of high rates of co-occurring medical and psychiatric conditions, autistic adults may have high AC exposure, and thus, may experience elevated ACB. However, no research has characterized AC exposure or examined its associations with cognitive outcomes in autistic adults. Autistic adults (40-83 years) recruited via Simons Powering Autism Research’s (SPARK) Research Match service self-reported their medication use (N=415) and memory complaints (N=382) at Time (T)1. At T2, two years later, a subset of T1 participants (N=197) self-reported on decline in cognition. Medications were coded using two scales of AC potency. A high proportion (48.2% to 62.9%, depending upon the AC potency scale) of autistic adults reported taking at least one medication with AC effects, and 20.5% to 26.5% of autistic adults reported clinically-relevant levels of AC medication (potency ≥3). After controlling for birth-sex and age, hierarchical linear regression models showed total ACB scores and AC potency values of ≥3 predicted greater memory complaints. Logistic regression models showed that AC medicines at T1 were associated with self-reported cognitive decline at follow-up two years later. Understanding AC medications—including potentially earlier AC polypharmacy—and their impacts on cognition (e.g., dementia risk) in autistic adults is warranted.