bluuebunny/crossref_metadata_2025 huggingface dataset:
FORMULACIÓN DE ELEMENTOS FINITOS VIGA-COLUMNA CON DISCONTINUIDADES EMBEBIDAS PARA MODELAR DAÑO EN ELEMENTOS PRISMÁTICOS DE CONCRETO REFORZADO
Authors: Juárez Luna Gelacio , Tenorio Montero Enrique
Published: January 2018

Se formulan elementos finitos viga-columna con discontinuidades interiores para modelar el desarrollo de articulaciones. En estos elementos, el daño se modela como el desarrollo de rótulas, dislocaciones transversales y discontinuidades axiales. Estos elementos finitos utilizan modelos constitutivos para considerar la capacidad de momento, fuerza cortante y fuerza axial, basados en la mecánica del daño y en pruebas experimentales reportadas en la literatura, las cuales incluyen el comportamiento constitutivo del concreto con acero de refuerzo. Para mostrar la capacidad de modelar el daño de los elementos finitos desarrollados, se presentan ejemplos numéricos de vigas y marcos de concreto reforzados sujetos a cargas que inducen daño. En estos ejemplos numéricos, las curvas de la carga contra el desplazamiento calculadas son congruentes con las reportadas en la literatura.
[Trans]formação do sujeito-ator, um caminho possível com e pela voz
Authors: Aguilar Gina María Monge , Castaman Aline
Published: January 2018

Este artigo apresenta um caminho possível para o trabalho da voz-sonoridade associada ao processo artístico- pedagógico desenvolvido com alunos-atores no Departamento de Artes Cênicas da UNICAMP, e, concomitantemente, uma interlocução com as observações realizadas pela estagiária -partícipe neste processo sob uma perspectiva da práxis via notas de rodapé.
Hay un duende en la voz: Técnica vocal y canto popular revisitados
Authors: Cangiano María , Apelbaum Tania
Published: January 2018

Grosso modo existe um costume referente ao canto popular, ao menos na Argentina, de não prestar importancia à técnica vocal e pensar que o canto popular quando mais distante do treinamento, mais autêntico é. No entanto, cedo ou tarde os cantores de música popular precisam recorrer ao treinamento vocal. Na maioria dos casos, ao menos naqueles cantores cujas vozes chamam a atenção, o treinamente vem do canto lírico. Propomos aquí uma série de práticas para o treinamento vocal que em si mesmas nos conectem com a nossa verdade, e nos permitam alcançar uma voz natural, rica, expressiva e, além de mais, saudável.
The Discovery of Synthetic Proteolytic Peptide
Authors: Nakamura Rina , Konishi Motomi , Taniguchi Masanari , Hatakawa Yusuke , Akizawa Toshifumi
Published: January 2018

After screening nearly 1000 synthetic peptides, a synthetic peptide termed JAL-AK22 (KYEGHWYPEKPYKGSGFRCIHI) derived from the BoxA domain in Tob1 protein was found to activate both unfolded and folded proMMP-7. In addition, JAL-AK22 showed auto-proteolytic activity. Interestingly, the smaller derivative of JAL-AK22 termed JAL-TA9 (YKGSGFRMI) also possessed auto-proteolytic activity and cleaved 2 fragment peptides (MMP18-33 and MMP18-40) derived from the prodomain of proMMP-7 under physiological conditions. These proteolytic activities were inhibited by AEBSF, a serine protease inhibitor. Our results demonstrate that a small synthetic peptide consisting of only 9 amino acids has serine protease-like activity and activates proMMP-7 by cleaving the prodomain region. We thus propose calling small peptides possessing with protease-like activity Catalytides (catalytic peptides). We expect that our findings will stimulate the development of novel Catalytides and related applications.
Quarks in a Polar Model
Authors: Salomatov Vladimir
Published: January 2018

Current-quark masses are compared to the rest masses allowed by the Helmholtz equation in a polar model. Within the uncertainty of the current u quark mass determination, the current quark mass coincides with the rest mass allowed by the Helmholtz equation in the polar model in accordance with the second root of the zero Neumann function. Current d quark mass coincides with the rest mass calculated in accordance with the third root of the Bessel zero function. On the basis of a comparison of these results with the results obtained earlier for ordinary real particles u and d quarks stability is discussed.
MARINERA NORTEÑA: TECNOLOGÍAS CORPORALES Y EDUCACIÓN ALTERNA
Authors: Benavides Daniel Orlando Díaz
Published: January 2018

La Marinera es la danza nacional del Perú cuyos portadores, desde el primer concurso organizado en 1960, se involucraron en un altísimo dinamismo social que ha engendrado una red o entorno social cerrado y complejo, una tecnología corporal diferenciada, un sistema de formación particular o sistema educativo alterno, mecanismos autónomos de profesionalización y de información, medios ágiles para actuar de manera sobresaliente en la sociedad y, sobre todo, formación de bailarines y bailarinas con cuerpos de altísima resolución estética que actúan exitosamente en los escenarios más exigentes del mundo. Este ensayo da cuenta de este proceso y apuesta por la hipótesis de la potenciación de los cuerpos, a partir de la danza, para responder con eficiencia a las exigencias cotidianas contemporáneas.
Los ímbrices de mármol del Traianeum de Italica
Authors: Vargas Vázquez Sebastián
Published: January 2018

The study of the material that we present in this article is part of the new research currently in progress on the Traianeum of Italica (Santiponce, Seville, Spain). The material under study corresponds to an assemblage of marble roof imbrices, the characteristics of which provide a new understanding of the build- ing, of its aesthetics and its statics. This, in turn, has led us to reflect on the nature of this architectural complex and, particularly, on its foundations, considering the enormous weight of the roof that we now know covered the Traianeum of Italica.
L'area forense di Forum Sempronii: nuovi dati architettonici e urbanistici alla luce degli scavi 2013-2017
Authors: Mei Oscar , Cariddi Lorenzo , Gasparini Massimo
Published: January 2018

Il presente contributo fornisce una preliminare analisi urbanistica e architettonica dell'area forense e delle relative strutture portate alla luce durante le campagne di scavo 2013-2017, presso il municipium di Forum Sempronii.
Allo stato attuale sono stati identi cati, a livello di fondazione, la piazza del foro e i portici che la delimitavano; sul lato Nord dello spazio forense sono stati identi cati tre templi, dei quali il Tempio A interamente scavato.
Al di fuori del limite orientale del forum e in posizione prospiciente alla via Flaminia, è stato rinvenuto, in buono stato di conservazione, una terza struttura con probabile funzione cultuale e amministrativa e identi cata come l'Augusteum di Forum Sempronii. Dai dati nora emersi, sembrerebbe possibile ipotizzare la pertinenza di tutte le strutture a una imponente riforma urbanistica e architettonica del municipium avvenuta in epoca augustea.
Tolfenamic Acid: A Modifier of the Tau Protein and its Role in Cognition and Tauopathy
Authors: Chang Joanna K. , Leso Allison , Subaiea Gehad M. , Lahouel Asma , Masoud Anwar , Mushtaq Foqia , Deeb Reem , Eid Aseel , Dash Miriam , Bihaqi Syed W. , Zawia Nasser H.
Published: January 2018

Background:

Tangles are deposits of hyperphosphorylated tau, which are found in multiple neurodegenerative
disorders that are referred to as tauopathies, of which Alzheimer's disease (AD) is the most
common. Tauopathies are clinically characterized by dementia and share common cortical lesions composed of
aggregates of the protein tau.

Objective:

In this study, we explored the therapeutic potential of tolfenamic acid (TA), in modifying disease
processes in a transgenic animal model that carries the human tau gene (hTau).

Methods:

Behavioral tests, Western blotting and Immunohistochemical analysis were used to demonstrate the
efficacy of TA.

Results:

Treatment of TA improved improving spatial learning deficits and memory impairments in young and
aged hTau mice. Western blot analysis of the hTau protein revealed reductions in total tau as well as in sitespecific
hyperphosphorylation of tau in response to TA administration. Immunohistochemical analysis for
phosphorylated tau protein revealed reduced staining in the frontal cortex, hippocampus, and striatum in animals
treated with TA.

Conclusion:

TA holds the potential as a disease-modifying agent for the treatment of tauopathies including
AD.
Correlation Between White Blood Cell Count and Insulin Resistance in Type 2 Diabetes
Authors: Mahdiani Armin , Kheirandish Masoume , Bonakdaran Shokoufeh
Published: January 2018

Background:

The role of chronic inflammation in insulin resistance states and the pathogenesis
of metabolic syndrome, cardiovascular disease and diabetes have been reported earlier. White
Blood Cell (WBC) count is an easy marker for estimation of systemic inflammation.

Objective:

This study is to clarify whether WBC count is associated with insulin resistance in type 2
diabetic patients.

Methods:

This cross sectional study was conducted in 283 patients with type 2 diabetes and in 283
healthy non diabetic subjects as control group. Data including: age, gender, blood pressure, height and
weight, history of smoking were collected for each patient. Fasting blood sugar, HbA1C, insulin, lipid
profiles, creatinine, Urine albumin to creatinine ratio, high sensitive C- reactive protein (HCRP) and
WBC was measured for all patients. WBC count was measured in control group. Two groups were
compared in WBC count. Insulin resistance was calculated with HOMA-IR formula. Association of
WBC count with insulin resistance and metabolic parameters was assessed in diabetic patients.

Results:

WBC count was significantly associated with body mass index, hypertension, and triglyceride
level. There was not significant association between WBC count and glycemic index and insulin resistance.

Conclusion:

An elevated WBC count (even in the normal range) is closely related to various components
of metabolic syndrome but not related to insulin resistance in type 2 diabetes.
Zr‐Metal Organic Framework and Derivatives for Adsorptive and Photocatalytic Removal of Acid Dyes
Authors: Lin Kun‐Yi Andrew , Yang Hongta , Hsu Fu‐Kong
Published: January 2018

To investigate effects of modification of MOFs on removal of acid dyes via adsorption and photodegradation, zirconium‐based MOF, UiO‐66, and its derivatives were synthesized. UiO‐66 derivatives were prepared by using amine (NH2)‐containing ligand and incorporating carbon nanotubes (CNTs) and reduced graphene oxide (RGO). During the synthesis UiO‐66‐NH2, UiO‐66‐CNT and UiO‐66‐RGO, were obtained, respectively. While UiO‐66‐NH2 showed the enhanced adsorption capacity for acid dyes owing to the electrostatic attraction, CNTs were found to be the most effective addition to enhance the adsorption of acid dyes. However, the addition of RGO in UiO‐66 (to form UiO‐66‐RGO) exhibited the highest removal efficiency via photodegradation compared to UiO‐66 and other derivatives probably attributed to its unique layered morphology. The presence of NH2, CNTs and RGO not only significantly improved the adsorption capacity for acid dyes but also enabled these UiO‐66 derivatives to exhibit photocatalytic activity under visible light irradiation.
Cardiorehabilitation of Patients with Acute Coronary Syndrome Who Were Performed Coronary Arteries Revascularization
Authors: Shved Mykola , Tsuglevych Lesja , Kyrychok Iryna , Boiko Tetiana , Levutska Larysa
Published: January 2018

In patients with acute coronary syndrome who were performed coronary arteries’ revascularization, in the postoperative period disorders of hemodynamics and heart rate variability often develop. The aim of our work was to optimize the cardiac rehabilitation of such patients by individualization of physical activity depending on the state of systolic and diastolic left ventricular dysfunction and heart rate variability.                 40 patients with acute coronary syndrome and coronary artery revascularization were included into the experimental group. The control group consisted of 20 patients of the same age, clinical and laboratory manifestations of ACS who were treated according to the protocol of Ministry of Health of Ukraine. In both groups of patients clinical efficacy of cardiac rehabilitation process was evaluated according to the dynamics of clinical symptoms, systolic and diastolic left ventricular function and heart rate variability.                 In patients with acute coronary syndrome and coronary artery revascularization in the initial state the clinical and laboratory signs of myocardial ischemia disappear, but subclinical and clinical manifestations of heart failure remain.                 During the first month of training, the original accelerated cardiac rehabilitation program leads to the decrease of systolic and diastolic signs of cardiac dysfunction and improves heart rate variability, which significantly improves the quality of life of these patients.                 For monitoring the efficacy and safety of the performance of cardiac rehabilitation program in patients with acute coronary syndrome and coronary artery revascularization, in addition to conventional methods (determination of heart rate, blood pressure, 6-minute test), it is useful to diagnose subclinical stage of heart failure by examination of systolic, diastolic function and vegetative regulation.
Biofilm formation analysis and molecular identification of copper-resistant bacteria isolated from PT Freeport Indonesia’s tailings
Authors: Massora Maria , Martani Erni , Sugiharto Eko , Sarwom Roberth , Sinaga Tumpal
Published: January 2018

Copper is an essential macronutrient for living organisms. Nevertheless, at high concentrations, it is toxic to most forms of life, including microorganisms. In this research, we examined the biofilm formation ability and identified the molecular characteristics of copper-resistant bacteria isolated from PT Freeport Indonesia’s tailings. Four bacteria isolates from PT Freeport Indonesia’s tailings were used in this study. Qualitative analysis of biofilm formation by copper-resistant bacteria was performed using the Scanning Electron Microscopy (SEM) method and Microtiter Plate Biofilm Assay. The results showed that the C53 isolate could be categorized as a strong biofilm former, and three other isolates (C38, C40, and C43) as medium biofilm formers. The identity of the selected isolates was based on 16S rRNA gene sequence analysis: C38 isolate had a 99% similarity to Bacillus cereus strain HM85, C43 isolate had a 99% similarity to Bacillus subtilis strain EN16, C40 isolate had a 99% similarity to Lycinibacillus fusiformis strain MB52, and C53 isolate had a 98% similarity to Pseudomonas aeuruginosa strain GGRJ21. The capability of the C53 isolate to form strong biofilm can be exploited in bioremediation processes aiming to remove copper from tailings.
Assessment of genetic diversity among surian Toona sinensis Roem in progenies test using random amplified polymorphic DNA markers
Authors: Jayusman Jayusman , Na’iem Muhammad , Indrioko Sapto , Hardiyanto Eko Bhakti , Nurcahyaningsih ILG
Published: January 2018

Surian Toona sinensis Roem is one of the most widely planted species in Indonesia. This study aimed to estimate the genetic diversity between a number of surian populations in a progeny test using RAPD markers, with the goal of proposing management strategies for a surian breeding program. Ninety-six individual trees from 8 populations of surian were chosen as samples for analysis. Eleven polymorphic primers (OP-B3, OP-B4, OP-B10, OP-H3, OP-Y6, OP-Y7, OP-Y8, OP-Y10, OP-Y11, OP-Y14, and OP-06) producing reproducible bands were analyzed for the 96 trees, with six trees per family sampled. Data were analyzed using GenAlEx 6.3, NTSYS 2.02. The observed percentage of polymorphic loci ranged from 18.2% to 50%. The mean level of genetic diversity among the surian populations was considered to be moderate (He 0.304). Cluster analysis grouped the genotypes into two main clusters, at similarity levels of 0.68 and 0.46. The first two axes of the PCoA explained 46.16% and 25.54% of the total variation, respectively. The grouping of samples into clusters and subclusters did not correspond with family and their distances, but the grouping was in line with the genetic distances of the samples.
La transformación de los conflictos. Abordajes desde una ética comprehensiva
Authors: Castro Augusto
Published: January 2018

El presente artículo trata de repensar la ética desde el horizonte de los conflictos socioambientales, y busca con ello avanzar hacia una perspectiva comprehensiva e interdisciplinaria. La reflexión presentada quiere contar con una nueva perspectiva de la ética que vaya más allá de una mirada eudaimonista o hedonista del pensar moral, y abrirla hacia una comprensión de los fenómenos sociales y ambientales. Para ello, el trabajo recoge la nueva reflexión sobre la noción de conflicto y el esfuerzo que significa la transformación del mismo como forma de superarlo. En esa orientación se proponen criterios como la comprensión de la historia del conflicto, los intereses de los actores y la tradición cultural de las personas. Una ética comprehensiva que toma en cuenta la multiplicidad de aspectos en los que se producen los conflictos, puede tener mucho éxito en la transformación de los mismos.
Presentación
Authors: Mansilla Ricardo
Published: January 2018

Presentación
Competencias Ciudadanas para la Paz en la formación de patrulleros de la Policía Nacional de Colombia
Authors: Patiño Álvarez Jorge Enrique
Published: January 2018

La investigación tuvo como objetivo crear un mecanismo que permitiera medir el nivel de conocimiento en competencias ciudadanas de los Patrulleros de la Policía de Colombia durante el proceso de formación, así mismo identificar debilidades, fortalezas y mejoras en la formación. La población estuvo conformada por estudiantes aspirantes a ejercer como patrulleros de una Escuela de formación policial. La investigación siguió un enfoque cuantitativo correlacional, donde se analizó variables de convivencia pacífica y paz, participación y responsabilidad democrática, pluralidad, multiculturalidad y valoración por las diferencias, asociadas a las competencias ciudadanas. Dentro de los principales hallazgos se evidenció el alto sentido de ciudadanía y el reconocimiento de los derechos, deberes, así como de los conceptos de sociedad y la importancia para de la construcción de la paz de Colombia. Así mismo es necesario que se fortalezcan conocimientos sobre los derechos fundamentales bajo el estudio de la Constitución Política de Colombia. La investigación concluyó que en la formación de patrulleros es de gran importancia el estudio de las competencias ciudadanas, más aún, por los caminos de paz que busca el país en la actualidad. Esto tiene una implicación y es que una vez egresen como profesionales, deberán aplicar todos los conocimientos de las competencias de conocimiento para la contribución de la paz de Colombia.
A JUVENTUDE COMO UM CALEIDOSCÓPIO E A POLÍTICA NACIONAL DE JUVENTUDE
Authors: Rego Noelia Rodrigues Pereira
Published: January 2018

Um grande leque se abre quando tomamos para nós o desafio de ter com as juventudes. Isso porquealém de ser uma categoria de certa maneira nova, em plena “desmistificação”, é uma categoria que aquidenominamos e a entendemos por caleidoscópica: carregada de significados e pertencimentos e, para tanto,difícil de ser apreendida. Por outro lado, constatar um Estado desigual é entender que não basta “acreditar paravencer”, mas é ver cada vez mais a necessidade da promoção de políticas públicas mais horizontais, quepriorizem a participação dos coletivos de juventude já no seu planejamento. Assim que, analisar com lucidez osdez anos de políticas públicas de juventude, nos faz rever pontos e trabalhar em cima deles seja para ampliá-los,seja para modificá-los, para que possamos de fato ir ao encontro dos quase 70 milhões de habitantes juvenis quea nação abarca e fazer políticas públicas COM eles e elas e não PARA eles e elas. É o que veremos.
Adesão à identificação do paciente em hospital universitário público
Authors: Girardi Camila , Fujii Neta Akie , Santos Daiana Tais Rheinheimer dos , Oliveira João Lucas Campos de , Oliveira Renata Pereira de , Maraschin Maristela Salete , Tonini Nelsi Salete
Published: January 2018

Estudo transversal cujo objetivo foi identificar a taxa de adesão à identificação do paciente hospitalizado, bem como os principais motivos para sua não aderência. A pesquisa foi realizada em hospital universitário público do Paraná, com uma amostra (n=748) de pacientes internados entre setembro a dezembro de 2016. A coleta de dados foi precedida por observação direta com registro da adesão à pulseira de identificação e motivos para não aderência em um dia aleatório não agendado de cada mês. Aos dados tabulados procedeu-se análise estatística descritiva em medidas de proporção. A taxa geral de adesão à identificação do paciente foi de 71,6%. O melhor resultado de adesão foi constatado no Centro Obstétrico (94,2%); e o pior, na Pediatria, com 61,4% de não adesão. O motivo de não aderência mais frequente se relaciona à perda da pulseira nos setores. Concluiu-se que a adesão à identificação do paciente no hospital ainda é deficitária, e que a melhor comunicação com os setores assistenciais e o serviço de internamento pode ser uma estratégia para a maior adesão.
Game Design Jomblo Keren As a Startup Marketing Product
Authors: Laviano Celvin , Sanjaya Ridwan , Prasetya Hendra
Published: January 2018

The number of competitors makes the competition in the game industrymore difficult if not able to read opportunities well. Because it takes theability to be able to take advantage of opportunities with the best. Bill Gates once quoted a word from Don Corleone that we must keep our friend close but our enemies even closer. Because of these competitors we will see various types of opportunities and opportunities that exist. The creation of "Jomblo Keren" game design will look at different types of aspects that can be used to get the right predictions to make the games acceptable by the market. These aspects include themes, games platform, visuals, gameplay, and stories.
Misperception in Understanding Soft Skills Concept: A Multi-Case Study in Elementary Schools of Indonesia
Authors: Musnandar Aries
Published: January 2018

Sejak Alfred Binnet dan Theodore Simon (1905) memperkenalkan IQ (Intelligence Quotient) banyak pihak menganggap IQ sebagai faktor penting keberhasilan unjuk kerja seseorang di berbagai sektor kehidupan tidak terkecuali sektor pendidikan.  Tujuan penelitian ini adalah untuk mendalami penting dan perlunya pengembangan soft skills siswa di sekolah-sekolah khususnya tingkat SD.  Penelitian menggunakan metode kualitatif dengan jenis studi kasus dan rancangan studi multi kasus yang menggaris bawahi kegiatan pembuatan makna, sebagaimana pendekatan interpretive research menjadi dasar memahami fenomena sosial dari aktivitas pendidikan. Berdasarkan temuan penelitian diketahui secara substantif bahwa pemahaman guru, kepala sekolah, staf terkait dan orang tua siswa terhadap  konsep soft skills masih kurang dan terbatas. Kegiatan belajar mengajar di sekolah berorientasi akademik dengan metode pembelajaran yang mengabaikan pentingnya pembentukan soft skills siswa. Disamping itu, soft skills dianggap tidak terkait dengan prestasi akademik, sehingga aktivitas pembelajaran kurang melibatkan potensi bagi peningkatan soft skills siswa. Di sisi lain ditemukan bahwa sekolah yang menaruh perhatian pada aspek-aspek pengembangan soft skills pada akhirnya dapat mengaktifkan potensi siswa meraih ketercapaian belajar akademik optimal. Akhirnya, secara formal dapat dikemukakan bahwa manajemen pembelajaran soft skills siswa perlu dan penting diterapkan dalam pendidikan khususnya di jenjang pendidikan dasar.
Geriatric and Student Perceptions following Student-led Educational Sessions
Authors: Janzen Kristin , Kormelink Lauren N. , Saum Lindsay , Nisly Sarah A.
Published: January 2018

Objective: The objective of this study was to measure the effect of student-led educational events on geriatric patient and student participant perceptions in a community setting.

Methods: Students led three events at a senior community center, focusing on learning and memory, sleep hygiene, and arthritis pain. The participants were geriatric patients who themselves were providers of support to homebound peers (“clients”) through an independently organized program. Geriatric participants completed pre- and post-event surveys to measure changes in familiarity with the topics. Student participants also completed pre- and post-event surveys that tracked changes in their comfort in working with the geriatric population.

Results: Each event demonstrated at least one positive finding for geriatric patients and/or their clients. Students reported increased comfort in working with and teaching the geriatric population following the first and third events, but not the second.

Conclusion: Student-led educational sessions can improve perceived health-related knowledge of geriatric participants while simultaneously exposing students to the geriatric patient population. Overall, both students and geriatric participants benefited from these events.

Practice Implications: Incorporation of single, student-led educational events could be mutually beneficial to students and the elderly population in the community and easily incorporated into any healthcare curriculum.

Funding:This work was supported by a Butler University Innovation Fund Grant.

Treatment of Human Subjects: IRB review/approval required and obtained

 

Type: Original Research
Cow`s milk protein allergy awareness and practice among Turkish pediatricians: A questionnaire-survey
Authors: Yüce Aysel , Dalgıç Buket , Çullu-Çokuğraş Fügen , Çokuğraş Haluk , Kansu Aydan , Alptekin-Sarıoğlu Aysugül , Şekerel Bülent Enis
Published: January 2018

Region-specific recommendations for the prevention, diagnosis, and treatment of cow`s milk protein allergy (CMPA) are not available in Turkey. This cross-sectional questionnaire-survey was designed to evaluate CMPA awareness and practice among Turkish pediatricians. A total of 410 pediatricians were included based on their voluntary participation. Questionnaires elicited demographic data and pediatricians` awareness and practice of CMPA in infants and children. Atopic dermatitis (91.5%), diarrhea (88.0%) and significant blood in stool (85.9%) were the most common symptoms considered suggestive of CMPA. Continuation of breast feeding via elimination of CMP containing products from maternal diet was the most commonly selected (79.0%) therapeutic option in exclusively breast-fed infants diagnosed with CMPA. Amino acid-based formula was the most commonly selected formula in a non-exclusively breast-fed infant with CMPA, for infants presenting with anaphylaxis (58.8%), enterocolitis (40.7%) or multiple food allergies (52.0%), and also for at-risk infants (40.2%). Earliest time to re-challenge was identified to be 6 months by 52.0% of pediatricians. In conclusion, our findings revealed high awareness of CMPA among Turkish pediatricians in terms of clinical presentation and first priority diagnostic tests. However, CMPA practice among Turkish pediatricians needs to be improved in terms of avoidance of other mammalian milks, selection of therapeutic formulas among non-exclusively breast-fed infants and at-risk infants consistent with guideline-based indications and cost-effectivity.
Evaluation of Tissue Doppler Echocardiographic Imaging findings in children with pulmonary hypertension
Authors: Akın Alper , Alehan Dursun , Aykan Hayrettin Hakan , Özkutlu Süheyla , Özer Sema , Karagöz Tevfik
Published: January 2018

Tissue Doppler Imaging has become an important prognostic marker that can be used in follow-up and determination of the prognosis in pulmonary hypertension patients. We compared the Tissue Doppler imaging parameters of 34 patients with pulmonary hypertension and 43 healthy controls. In addition, Brain-Natriuretic Peptide levels, pulmonary artery systolic pressures measured with echocardiography, 6-minute walking tests and New York Heart Association functional classification were compared. Among patients with Eisenmenger syndrome and idiopathic pulmonary hypertension, Tissue Doppler imaging parameters were mostly similar. In patients with New York Heart Association functional class 3, mitral septal annulus E/Ea (p=0.050) and mitral lateral annulus myocardial performance index (p=0.009) were higher than class 2 patients. In patients with higher Brain Natriuretic Peptide level, mitral lateral annulus and tricuspid septal annulus Ea/Aa values were lower (p=0.046 and < 0.001 respectively); tricuspid septal annulus E/Ea and interventricular septum myocardial performance index values were higher than in patients with normal Brain-Natriuretic Peptide level (p=0.006). In conclusion tissue Doppler imaging findings were significantly impaired in children with pulmonary hypertension compared to the control group. Findings were similar in patients with idiopathic pulmonary hypertension and Eisenmenger syndrome. Mitral lateral annulus myocardial performance index value may have a prognostic importance due its significant association with poor functional class. Due to the significant associations between mitral lateral annulus, tricuspid septal annulus Ea/Aa, tricuspid septal annulus Ea and E/Aa, interventricular septum-myocardial performance index values and brain natriuretic peptide levels, these parameters may be used in evaluating response to therapy.
Clinical features and treatment results in children with hemangioma
Authors: Ataş Erman , Koç Ozan , Artık Hatice A
Published: January 2018

Hemangioma is a frequent disease which has a proliferative and involution phase. In this single center retrospective study, we evaluated clinical and therapeutic features of hemangiomas in children (n: 49). The median (range) age at onset and at admission were 21 days (10 days-156 months) and 7 months (0.25-192 months), respectively. The localization of lesions was: head region (n: 28; 57.2%), trunk (n: 8; 16.3%) trunk, limb (n: 8; 16.3%), and neck region (n: 5; 10.2%) neck region. Seventeen patients (34.7%) were treated. Following treatments were used: propranolol alone in 12 (24.5%) patients, steroid alone in 2 (4.1%) patients, prednisone plus propranolol in 2 (4.1%) patients, and propranolol plus surgery in 1 (2.0%) patient. The number of hemangioma (n > 1) (p = 0.026, OR = 9.5, 95% CI 1.3-69.2) and treatment other than observation (p = 0.008, OR = 10.5, 95% CI 1.8-59.1) were significant predictors in the univariate analysis; treatment other than observation was an independent predictor for clinical response (p = 0.014, OR = 9.8, 95% CI 1.5-90.9).
An infant with glutaric aciduria type IIc diagnosed with a novel mutation
Authors: Işıkay Sedat , Yaman Ayhan , Ceylaner Serdar
Published: January 2018

Glutaric aciduria type II is a rare inborn error of metabolism. The clinical picture is highly variable with symptoms ranging from acute metabolic decompensations to chronic, mainly muscular problems or even asymptomatic cases. Herein we described a 7-month-old female patient presented with respiratory failure and diagnosed with glutaric aciduria type II via whole exome sequencing that exhibited one known and a novel mutation. Her blood and urine analyses were all normal. After the diagnosis, dramatic and sustained improvement on a low-fat, low-protein, and high-carbohydrate diet supplemented with oral riboflavin and carnitine was determined. In especially hypotonic patients with unknown etiologies, though the blood and urine analyses are normal, glutaric aciduria type II should also be kept in mind and genetic tests may be required for the diagnosis.
Occipital cortex dysgenesis with white matter changes due to mutations in Laminin a2
Authors: Yiş Uluç , Dixit Vishal , Işıkay Sedat , Karakaya Mert , Baydan Figen , Diniz Gülden , Polat İpek , Hız-Kurul Semra , Çırak Sebahattin
Published: January 2018

Laminin α2 related congenital muscular dystrophy is one of the most common congenital muscular dystrophies of childhood with or without clinical evidence of central nervous system involvement. It may be associated with significant white matter abnormalities resembling leukodystrophies. In this study, we elaborated on two cases with laminin α2 related congenital muscular dystrophy who had occipital cortex dysgenesis in addition to characteristic white matter abnormalities. Although laminin α2 related congenital muscular dystrophy with white matter abnormalities is known, the association with occipital cortex dysplasia has been not well recognized by clinical colleagues.
Las comunidades afrocolombianas y su realidad en el Estado Social de Derecho: ¿Hacia su reconocimiento jurídico en un mundo de discriminación social? Casos Neiva, Baraya y La Plata: aspectos laborales, afectivos y educativos
Authors: Quintero Zambrano Edinson , Quintero Castro Germán David , Guillermo Cardozo Luis , Abella de Fierro Martha Cecilia
Published: January 2018

Con la Constitución Política de 1991, el pueblo Afrocolombiano  renace y adquiere la relevancia que se merece en un Estado Social de Derecho. La diversidad étnica y cultural de la Nación es reconocida como principio fundamental y así lo registran los artículos 7, 8, 9, 68, 70 y 72. Corresponde identificar si la sociedad se ha apropiado de estas posturas jurídicas permitiendo a los afrocolombianos hacer parte de su entorno no solo desde lo constitucional sino desde lo cotidiano. Con este texto se busca evaluar si aquel discurso, ha tenido o no aplicabilidad en los Municipios de  Neiva, Baraya y La Plata – Huila - en lo concerniente a la vida laboral, afectiva y educativa de estos grupos.
La acción popular y el desmonte de su perfil preventivo y correctivo a favor de la corrupción con la derogatoria del artículo 40 de la ley 472 de 1998
Authors: Álvarez Tafur Mauricio José
Published: January 2018

La Acción Popular como una herramienta de control preventivo y correctivo a la administración pública en Colombia, ha sufrido un menoscabo importante en materia de protección de los derechos colectivos a la moralidad administrativa y el patrimonio público, debido a la derogatoria del artículo 40 de la ley 472 de 1998, vía ley 1425 de 2010, reforma que suprimió el incentivo que se establecía por el juez administrativo por un monto  del 15 % del dinero recuperado en eventos de corrupción administrativa y en los cuales la participación del actor popular había sido clave. Los objetivos de este escrito  reflexivo es ofrecer en primer lugar una visión de los efectos nocivos que se han derivado por la derogatoria reseñada del incentivo económico y de la responsabilidad patrimonial solidaria entre el contratista y servidor público que concurrían en la práctica inmoral, y en segundo lugar realizar una valoración de cómo ha debido abordarse  la reforma a la ley 472 de 1998 frente al tema del incentivo que se reconocía en el artículo 40 de ley 472 de 1998.
Reflexiones en torno a la autonomía tributaria de las entidades territoriales en el contexto del estado social de derecho
Authors: Ochoa  Maldonado Omar Alfonso
Published: January 2018

Uno de los cambios de mayor trascendencia que se consagró en la Constitución Política de 1991, fue el reconocimiento de ciertos niveles de autonomía en  determinadas materias a las entidades territoriales, en procura de materializar el postulado de la descentralización administrativa como característica del modelo de Estado.   Una de esas esferas en las que el Constituyente quiso que las entidades territoriales gozarán de un margen de autonomía en el ámbito de su jurisdicción, fue en temas de talante tributario, resaltándose que para el efecto, esté tipo de entidades están facultadas para decretar imposiciones tributarias, las cuales deben haber sido creadas o autorizadas previamente por el legislador en el ámbito nacional.  El propósito palmario de este trabajo, es auscultar la naturaleza y alcance de la citada autonomía fiscal de las entidades territoriales, en el contexto del Estado Social de Derecho, como modelo jurídico político prohijado por el Constituyente y las repercusiones de esa relación simbiótica centro – periferia, en el devenir fiscal del Estado, frente al proceso de descentralización administrativa y la profundización de la democracia participativa, apelando para ello a la producción jurisprudencial generada en la materia.
El diálogo entre el Tribunal Constitucional de Chile y la Doctrina
Authors: Peña Torres Marisol
Published: January 2018

La evolución de la jurisprudencia del Tribunal Constitucional chileno muestra, a través de sus distintas etapas, un recurso cada vez más permanente a la doctrina, nacional y extranjera, como a la jurisprudencia comparada, lo cual se estima fundamental frente a su tarea de delimitar el sentido y alcance de conceptos jurídicos indeterminados como los que se contienen en la Carta Fundamental.
El sentido del texto jurídico y la interpretación ética en el Derecho
Authors: Dávila Carlos Mario
Published: January 2018

El presente artículo, se presenta en dos momentos. En primer lugar, aborda el tema de la interpretación y los  sentidos del texto jurídico, demostrando que estos no poseen una verdad en sí mismos y contario a lo que se cree, señalan varios e infinitos significados. En segundo lugar, propone un concepto de la interpretación ética en derecho de los textos jurídicos,  los cuales son fuente esencial del conocimiento para todos los juristas, y a su vez demuestra cómo esta interpretación ética puede ser utilizada en la aplicación de derechos fundamentales. Todo lo anterior  teniendo en cuenta que en el campo de los estudios jurídicos, el margen de la interpretación es limitada y por tanto juega un papel importante el talento que debe poseer el individuo al momento realizar este ejercicio.
Las formas de Estado en Colombia vistas a través de su historia constitucional.
Authors: Rivera Ledesma Ángela María , Rincón Andrade Diana Marcela , Saldaña Hernández Martín Emilio , Ángel Díaz Renán Mauricio , Pastrana Aristizabal Andrés Orlando , Gómez García Carlos Fernando
Published: January 2018

La independencia nacional fue sin duda el primer paso que dio la historia constitucional colombiana hacia su nacimiento, pues siendo Colombia un país independiente debía existir el Contrato Social para la consolidación efectiva del Estado con los derechos y libertades de cada uno de sus integrantes. Con ocasión del Bicentenario de la independencia de Colombia, es una obligación de la academia consolidar los procesos de evolución del Estado colombiano en todos sus ámbitos. La concepción de Estado que existe hoy en día a la luz de la Constitución Política de Colombia de 1991, ha sido una evolución donde el concepto del mismo, concebido como Estado social de Derecho, es el fruto de intentos fallidos de hallar la forma de Estado más pertinente para Colombia, que ha sufrido variaciones en sus instituciones políticas y numerosos intentos de organizarse a través de constituciones.La historia Constitucional  muestra la evolución que ha tenido el país en dicha materia, y aunque la Iglesia Católica, la violencia y la lucha por el poder han sido protagonistas activos desde la época de la independencia hasta la actualidad, la consolidación del derecho constitucional colombiano no es una quimera, por el contrario el fortalecimiento del mismo con el correr de los tiempos ha sido su característica principal.Así las cosas, el derecho constitucional ha tratado de dar forma al Estado colombiano. De principios monárquicos, en menos de cien años se pasó a ser una república democrática con un sistema de gobierno presidencialista y en menos de doscientos años, un Estado Social de Derecho. Y aunque la democracia ha sido duramente golpeada por fenómenos sociales ya mencionados y políticos, como el Frente Nacional, el derechoconstitucional ha salido avante y se ha impuesto sobre los obstáculos que la historia ha mostrado.En ese orden de ideas, el presente trabajo permitirá conocer a grandes rasgos, la historia del derecho constitucional, las características constitucionales que  ha tenido desde 1810 hasta 1886 así como diferentes fenómenos sociales, políticos y económicos que influyeron en el desarrollo y evolución del Estado colombiano y su Carta Fundamental.
Hacia una formulación analítica de victimarios y/o víctimas, enfoques de derechos económicos, sociales y culturales (DESC)
Authors: Vargas Calderón Luis Fernando
Published: January 2018

La presente investigación es el resultado de un caso hipotético formulado a estudiantes para establecer los avances de los contenidos impartidos en el aula de clase.Los delitos cometidos por niños, niñas y adolescentes resulta cada vez más una situación inestable que desborda todo contexto superfluo de políticas públicas orientadas con la disminución de tasas de criminalidad y la búsqueda de una vida digna a sectores poblaciones heterogéneas los unos con los otros.
Tres presupuestos para el reconocimiento de los principios generales del Derecho como fuente del ordenamiento jurídico cubano
Authors: Bruzón Viltres Carlos Justo , Palacio Castillo Lianet B.
Published: January 2018

En el presente artículo se realiza un análisis en torno a la necesidad de plantear presupuestos para el reconocimiento de los principios generales del Derecho como fuente del ordenamiento jurídico cubano. La investigación parte de la problemática identificada sobre la indeterminación del sistema de fuentes jurídico-formales en el Derecho cubano, entre ellas los principios generales. Como resultado principal se aportan tres presupuestos básicos necesarios para reconocer el valor de fuente a los principios generales del Derecho, contribuyendo con ello a la sistematización e integración del ordenamiento jurídico cubano.
Predicamentos de la democracia en Serbia
Authors: Vukadinoviæ Gordana , Avramoviæ Dragutin
Published: January 2018

Las estadísticas de 2013 en Serbia muestran que casi el 60% de la población total son propietarios de ordenadores, lo cual es más del 5% que en el 2012. Además, cerca del 56% tienen acceso al internet, lo que aumentó en un 8% con respecto al año pasado. Lo anterior, hace que sea un desarrollo rápido, continuo y sólido para el uso de las tecnologías de la información y las comunicaciones (TIC) en la gestión de las diferentes funciones del Estado. El primer paso ya se hizo en la explotación de las diversas formas de la administración, que se limitó principalmente a los servicios electrónicos, mejorando la anterior tradición burocrática, en la comunicación entre los ciudadanos y la administración del Estado. Además, la administración incluyó los primeros intentos del proceso de participación habilitando a los ciudadanos para exponer su opinión a través de la discusión pública en los procesos de redacción de la ley, así como en las diversas formas de debate llevado a cabo en el portal web especializado del Gobierno.
Tiempo y proceso en la era digital
Authors: Cabral Coutinho Carlos Marden , De Magalhães Barros Flaviane
Published: January 2018

El artículo pretende analizar la relación entre el tiempo y el proceso en la era digital, específicamente desde la perspectiva de la democracia constitucional. La pregunta acerca de la duración fue siempre central en las discusiones sobre el proceso, el tema actual radica en cómo poner en práctica una mayor agilidad en los juicios. En la era digital, con la posibilidad de recurrir al proceso virtual (que ya sucede en muchos países, como Brasil, Italia y Portugal), ha surgido un nuevo campo de posibilidades en el que se superó la burocracia por instalaciones judiciales inherentes de un mundo digital. Ante tal novedad, existen muchos dispositivos utilizados para juzgar un número creciente de casos tratados en menos tiempo. Resulta que el tiempo del proceso no se pueden eliminar fácilmente, porque está directamente involucrado en el ejercicio de garantías como el derecho de contradicción y el derecho de defensa (proceso de duelo de la ley); así, como la tecnología les permite juzgar en un esquema de las líneas de montaje, es necesario preservar un mínimo de tiempo que hace posible que las partes puedan ejercer los derechos que están garantizados por la Constitución. Ante esta cuestión, lo que se propone es examinar sí existen límites a la aceleración temporal que puede ser promovida por los medios digitales. El objetivo es demostrar que, incluso con los recursos digitales disponibles, no todos los dispositivos de aceleración deben ser admitidos, porque algunos de ellos pueden representar un compromiso por parte de la acción completa en la Corte.
Effects of the Imposter Phenomenon on Measures of Assertiveness in Female Professionals in South Africa
Authors: Nakazwe-Masiya Lyapa , Price Gavin , Hofmeyr Karl
Published: January 2018

Assertiveness is arguably one of the strongest predictors of success among business leaders and professionals. The study focuses on imposter phenomenon (IP), which occurs when an individual, normally considered to be a high achiever, undergoes an internal experience of feeling like an intellectual fraud or experiences a fear of failure upon achieving success, and the relationship of IP with assertiveness. Due to an absence of research on the relationship between IP and assertiveness, particularly in professionals in South Africa, this study investigates the way these two variables relate to each other. The purpose of this study is to 1) investigate whether IP is prevalent in female professionals in South Africa, 2) investigate whether IP and assertiveness are correlated and 3) determine whether IP is a predictor of assertiveness. The study was conducted on working professionals in South Africa (N = 165) and questionnaires were distributed online. The instruments used were the Clance Imposter Phenomenon Survey and elements of the Adaptive and Aggressive Assertiveness Scales. The professionals assessed were drawn from different industry sectors and across all job functions. The results suggest that IP is prevalent in professionals in South Africa and bears a moderately negative relationship to assertiveness. Another finding was that IP is a negative predictor of assertiveness. Gender also had an effect on the relationship between the two variables; the relationship was only found to be significant among women when the sample was split.
Drawing the Line between Dismissal for Alcoholism (Incapacity) and Dismissal for Drunkenness (Misconduct). Are the Boni Mores Compromised?
Authors: Phulu Thandekile
Published: January 2018

In South Africa employees are protected by various pieces of legislation. Section 23 of the Constitution of the Republic of South Africa 1996 provides for a right to fair labour practice. In its preamble the Labour Relations Act 66 of 1995 (hereafter referred to as the LRA) states that the purpose of the Act is to advance economic development, social justice, labour peace and democratisation of the workplace. The LRA also states that one of its objectives is to give effect to and regulate the fundamental rights conferred by section 27 of the Constitution. The Occupational Health and Safety Act as amended by the Occupational Health and Safety Amendment Act 181 of 1993 provides for the health and safety of persons at work and for the health and safety of persons in connection with the use of plant and machinery. The LRA provides for dismissal for incapacity and dismissals for misconduct. It also differentiates between the two. The LRA provides for both substantive and procedural fairness when dismissing an employee for incapacity and misconduct. This paper will examine the rationale behind differentiating between dismissal for drunkenness and dismissal for alcoholism.