bluuebunny/crossref_metadata_2025 huggingface dataset:
A Comparative Study Between Pemetrexed and Taxanes as First Line Treatment of Metastatic Lung Adenocarcinoma
Authors: Qahtan Al-Salihi, Sarmad , Sabieh Al Zubaidi Azhar
Published: June 2024

Background: Adenocarcinoma of the lung is the most common type of lung cancer. Platinum agents in combination with other chemotherapy are currently the cornerstone for chemotherapy of advanced cases with metastasis.
Objective: To compare the response rate of pemetrexed doublets versus taxanes doublets in patients with metastatic lung adenocarcinoma.
Patients and Methods: This a prospective study that included 60 patients with pulmonary adenocarcinoma. Those patients received a platinum based doublet chemotherapy with additional treatment protocol; combined with either pemetrexed or taxanes (paclitaxel or docetaxel) with 30 patients in each arm. Tumor size, response rate and side effects of chemotherapy were evaluated in both arms.
Results: The median reduction in tumor size in pemetrexed and taxan arms were 4.72 cm2 and 6.53 cm2 respectively. Nausea, fatigue, constipation and anorexia were more common in pemetrexed arm, while leukopenia, arthralgia and peripheral neuropathy were more common in taxan arm. Conclusion: Serious side effects such as leukopenia, and peripheral neuropathy were more common in taxan than pemetrexed arm. Pemetrexed is preferable to use as a fist line treatment for patients with metastatic adenocarcinoma of the lung.
Nrg1 intracellular signaling regulates the development of interhemispheric callosal axons in mice
Authors: Rodríguez-Prieto Ángela , Mateos-White Isabel , Aníbal-Martínez Mar , Navarro-González Carmen , Gil-Sanz Cristina , Domínguez-Canterla Yaiza , González-Manteiga Ana , Del Buey Furió Verónica , López-Bendito Guillermina , Fazzari Pietro
Published: June 2024

Schizophrenia is associated with altered cortical circuitry. Although the schizophrenia risk geneNRG1is known to affect the wiring of inhibitory interneurons, its role in excitatory neurons and axonal development is unclear. Here, we investigated the role of Nrg1 in the development of the corpus callosum, the major interhemispheric connection formed by cortical excitatory neurons. We found that deletion of Nrg1 impaired callosal axon development in vivo. Experiments in vitro and in vivo demonstrated that Nrg1 is cell-autonomously required for axonal outgrowth and that intracellular signaling of Nrg1 is sufficient to promote axonal development in cortical neurons and specifically in callosal axons. Furthermore, our data suggest that Nrg1 signaling regulates the expression of Growth Associated Protein 43, a key regulator of axonal growth. In conclusion, our study demonstrates that NRG1 is involved in the formation of interhemispheric callosal connections and provides a novel perspective on the relevance of NRG1 in excitatory neurons and in the etiology of schizophrenia.
East Asian Landscapes and Legitimation : Localizing Authority Through Sacred Sites in China and Vietnam
Authors: Koppen Yasmin
Published: June 2024

The conquest of Sichuan and Vietnam by the Chinese Empire led to very different outcomes. This volume examines the negotiations between central authority and local autonomy, the physical manifestations of socially constructed identities, and the transformation of sacred spaces which reflect broader social, political, and religious currents. It also offers a method to study spatial-social interactions in historical settings that provides insights into dynamics of power imposition and identity negotiation in local contexts. Experiential Architecture Analysis (EAA) serves to explore the interplay of local traditions, transcultural ideology transfer, and sacred water sites in the peripheries of Chinese culture. It analyzes the spatial ensembles of sacred sites regarding their roles for legitimation, dominance, and social resistance, while highlighting the agency of consumers to redefine spatial media. All scholars of Chinese and Southeast Asian History, of Religious Studies or Cultural Anthropology find in this volume valuable insights for their research, especially where it concerns areas lacking reliable written sources.
Bridging the Gap. Adaptive Reuse of Derelict Heritage Architecture
Authors:   , Brooke Rose
Published: June 2024

This research portfolio will demonstrate adaptive re-use as a technique to find usable solutions to protected heritage architecture that has fallen into disarray and is consequently unusable. This thesis aims to provide a precedent specifically for buildings of this condition, through adaptive reuse that respects the heritage significance while also encouraging a continuation of use in a modern context. This research is specifically centered around Carlile House, a category one heritage protected building that has fallen into disarray due to complications with landowners and the limitations from the buildings protected status. Using appropriate modern design, as well as heritage preservation techniques, this portfolio aims to generate a solution to Carlile House that benefits all parties and avoids neglect and eventually, demolition. The main outcome of this thesis is a proposed design that is relevant and informed by each previous stage, that satisfies restraints that have led to the building being left in a poor condition, creating a precedent for future projects of a similar nature. The importance of this work, is that it will contribute to this niche category of buildings that are currently dealt with case by case, and add to the material that sets out guidelines for buildings in similar situations.
Comparison of Clinical Effects Between Minimally Invasive Laparoscopic Surgery and Laparotomy in Treating Ovarian Endometriosis Cysts
Authors: Yao Yao
Published: June 2024

Objective: To compare the clinical effects of laparoscopic minimally invasive surgery and laparotomy in the treatment of ovarian endometriosis cysts. Methods: 66 patients with endometriosis cysts admitted to our hospital from December 2022 to December 2023 were selected as the study subjects and randomly divided into a control group (n = 33) and an observation group (n = 33). The control group was treated with laparotomy, and the observation group was treated with minimally invasive laparoscopic surgery. The surgical indexes, ovarian function indexes, and complications were observed. Results: All surgical indexes of the observation group (surgical time, intraoperative blood volume, hospital stay, postoperative antibiotic use time) were significantly better than the control group, (Pmean < 0.001). After surgery, the E2 score of ovarian function indexes in the observation group was higher than that in the control group, while the luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels were lower than those in the control (t = 5.246, t = 5.173, t = 3.535, Pmean < 0.001). Lastly, the overall incidence of complications in the observation group (1/3.03%) was lower than that in the control group (8/24.24%), (χ2 = 4.632, P < 0.05). Conclusion: Minimally invasive laparoscopic surgery is more effective than laparotomy in treating ovarian endometriosis.
Significance of Mid-Pregnancy Down Syndrome Risk Screening in Predicting Adverse Maternal and Fetal Outcomes
Authors: Yu Qiuzhi , Quan Hong , Lv Yujie
Published: June 2024

Objective: To investigate the value of mid-pregnancy Down syndrome risk screening in predicting adverse maternal and fetal outcomes. Methods: 536 mothers who underwent mid-pregnancy screening for Down syndrome at Chengyang District Maternal and Child Healthcare and Family Planning Service Center from January 2021 to December 2022 were selected for retrospective analysis. The risk was calculated using the Asian population database in the American prenatal screening software PRISCA 4.0, combined with the age, gestational week, and body mass of the day of the pregnant women's blood collection. Results: The screening results showed that there were 469, 54, and 13 cases in the low-risk, critical-risk, and high-risk groups, respectively, and there were no statistically significant differences in the age and body mass of each group (P > 0.05). However, there was a significant difference between the adverse fetal outcomes in low-risk, critical-risk, and high-risk groups (P < 0.05); and the screening results showed that there was a significant difference between the adverse maternal outcomes in the low-risk, critical-risk, and high-risk groups (P < 0.05). Conclusion: There is a relationship between the high risk of Down syndrome detected through screening and adverse maternal and fetal outcomes. Besides, the false positive and negative rates of Down syndrome screening results are positively correlated with adverse maternal and fetal outcomes.
Clinical Exploration of Immunosuppressants Combined with Abiraterone in the Treatment of Metastatic Castration-Resistant Prostate Cancer
Authors: Ma Lin
Published: June 2024

Prostate cancer is a malignant tumor with a high incidence in elderly men. In recent years, with the improvement of people’s living standards and the advancement of detection technology, the incidence of prostate cancer has been increasing year by year. Castration-resistant prostate cancer (CRPC) is a highly challenging type of advanced prostate cancer treatment, which clinically shows resistance to hormonal deprivation therapy. The overall treatment efficacy of CRPC is currently poor and further relevant therapeutic studies are needed to improve patient survival and quality of life. Immunosuppressants can play a role in combating the immune system of tumors, and abiraterone has also achieved remarkable results in prostate cancer treatment. This study will investigate the possible clinical effects and safety of immunosuppressants combined with abiraterone in the treatment of metastatic CRPC. The population-based study will provide clinicians with more effective treatment options, as well as enhance the understanding of novel combination therapy strategies to be implemented in the future for such patients.
Analysis of Hospital Budget Management Control Based on Smart Hospital
Authors: Chen Yuqi
Published: June 2024

Hospitals are crucial healthcare facilities where patients seek treatment, and effective budget management within hospitals significantly impacts their operational efficiency and financial performance. In the age of information technology and advanced healthcare solutions, the emergence of smart hospitals represents a new trend in the medical industry’s evolution. Leveraging modern information technology can enhance the development of hospital IT systems and drive budget management toward greater intelligence. This paper begins by analyzing the influence of smart hospitals on hospital budget control. It then examines the current state of budget management control within smart hospitals. Finally, it proposes several strategies for budget management control in smart hospitals, aiming to provide guidance for relevant stakeholders.
Application and Satisfaction Analysis of Humanized Quality Nursing Intervention in the Care of Patients with Critical Respiratory Failure
Authors: Xu Li
Published: June 2024

Objective: To implement humanized quality care in critical respiratory failure nursing, observe the effect, and analyze the satisfaction. Methods: 80 patients with severe respiratory failure were divided into 40 cases per group (admitted from February 2022 to December 2023) by double-blind method, the control group performed routine care, and the observation group was given humanized quality care. Results: After the nursing care, two respiratory function indexes of the observation group were lower than those of the control group, and two pulmonary function indexes were higher than those of the control group (P < 0.05); regarding the complication situation, the incidence rate of the observation group was lower (P < 0.05); regarding the nursing care satisfaction situation, the observation group had a higher level of total satisfaction (P < 0.05). Conclusion: The application of a humanized quality nursing intervention model in the care of critical respiratory failure can actively improve patients’ respiratory status and lung function, reduce complications, and satisfy patients.
Evaluation of the Efficacy of Alanyl-Glutamine for Nutritional Support in Septicemia
Authors: Hu Xiulan , Yang Hongfeng , Wang Chun , Bai Lu
Published: June 2024

Objective: To evaluate the therapeutic efficacy of alanyl-glutamine (Ala-Gln) in the nutritional support of sepsis. Methods: 120 cases of sepsis patients admitted to the hospital in the past three years were selected and grouped by randomization method, Group A was treated with Ala-Gln, and Group B was treated with conventional nutritional support therapy, and the therapeutic effects were compared. Results: Before treatment, there was no difference in nutritional indexes, immune function indexes, and inflammatory factors between the two groups (P > 0.05). After treatment, the nutritional indexes of Group A were higher than those of Group B, the immune function indexes were higher than those of Group B, and the inflammatory factors were lower than those of Group B (P < 0.05). Except for mortality, the regression of group A was better than that of group B (P < 0.05). Conclusion: Ala-Gln can improve the nutritional indexes of septicemia patients during the treatment period, enhance their immune function, reduce the inflammatory response of the body, and promote the regression of the disease.
Effectiveness of Low-Temperature Plasma Adenoidectomy Combined with Bilateral Tonsillectomy in the Treatment of Snoring in Children and Its Effect on Sleep Quality
Authors: Yan Huanfa , Yan Jiping , Li Qingmin , Gu Chunfang , Liu Jianxu
Published: June 2024

Objective: To evaluate the therapeutic effect of low-temperature plasma adenoidectomy (abbreviation: adenoid low-temperature plasma excision) coupled with tonsillectomy (bilateral) on snoring in children. Methods: Seventy-six cases of snoring children treated in the hospital between November 2020 and November 2023 were selected. 38 cases of children in Group A agreed to surgery and were admitted to the hospital for surgical treatment and were treated with adenoid cryo-plasma excision combined with tonsillectomy (bilaterally), and 38 cases of children in Group B did not agree to outpatient conservative treatment for surgery, and the results of the treatment were compared. Results: Before treatment, there was no difference between the ventilation function indexes, sleep quality scores, and quality of life scores of the two groups compared with each other (P > 0.05). After treatment, the ventilation function indexes of Group A were better than Group B, and the sleep quality score and quality of life score were higher than that of Group B. The total effective rate of Group A was higher than that of Group B (P < 0.05). Conclusion: Adenoid cryo-plasma excision combined with tonsillectomy (bilateral) can improve the quality of life, ventilation function, and sleep quality of children with snoring, and can enhance the efficacy.
Clinical Study on Respiratory Medicine Treatment of Chronic Obstructive Pulmonary Disease Combined with Respiratory Failure
Authors: Yu Jianhua
Published: June 2024

Objective: To explore the respiratory medicine treatment methods for treating chronic obstructive pulmonary disease (COPD) combined with respiratory failure. Methods: 70 cases of COPD patients with combined respiratory failure admitted to our hospital from January 2021 to January 2023 were selected as the study subjects, and randomly divided into the control group and the experimental group, each with 35 cases. The control group received only conventional treatment, and the experimental group received non-invasive positive pressure ventilation, and the treatment effects and changes in the levels of IL-18, hs-CRP, and CES2 inflammatory factors were observed and evaluated in the two groups. Results: There was no significant difference between the general data of the two groups (P > 0.05); after treatment, the total effective rate of clinical efficacy of the observation group (91.43%) was significantly higher than that of the control group (71.43%), and the difference showed a significant correlation (P < 0.05); after treatment, the level of inflammatory factor of the observation group was significantly reduced compared with that of the control group, and the difference showed a highly significant correlation (P < 0.001). Conclusion: The non-invasive positive pressure ventilation treatment program significantly improves the therapeutic effect, effectively controls the level of inflammatory factors, and improves the health status of patients when dealing with patients with chronic obstructive pulmonary disease accompanied by respiratory failure, showing a good clinical application prospect.
Impact of a Nurse-Led Chronic Disease Management Intervention Model on Quality of Care and Satisfaction of Maintenance Hemodialysis Patients
Authors: Wang Lanlan , Li Jing , Shen Yunxiang , Dai Guijun , Guo Lingling , Zhuang Chunxiang
Published: June 2024

Objective: To explore the impact of a nurse-led chronic disease management model on the quality of care and satisfaction of maintenance hemodialysis patients. Methods: 72 patients who received maintenance hemodialysis (MHD) from June 2021 to March 2022 were selected to undergo the nurse-led chronic disease management model. The hemodialysis indexes, nutritional status, and the occurrence of adverse events were assessed after 24 weeks of the intervention, and patients’ satisfaction was investigated and analyzed. Results: Comparing pre-intervention and after 24 weeks of intervention, urea reduction rate and urea clearance were improved but not statistically different (P > 0.05), but β2-microglobulin was significantly reduced compared with pre-intervention (P < 0.05); after 24 weeks of intervention, the effect of decreasing blood calcium, parathyroid hormone, and potassium levels was not obvious (P > 0.05), and the level of blood phosphorus decreased significantly compared with pre-intervention (P < 0.01), albumin and hemoglobin levels were increased and better than before intervention (P < 0.05); after 24 weeks of intervention, the incidence of intradialytic hypotension and hypertension was lower than before intervention (P < 0.05), and the total incidence of complications was significantly lower than before intervention (P < 0.01); there was no significant difference in the Self-Depression Scale scores after 24 weeks of intervention (P > 0.05), and Self-Anxiety Scale scores were significantly lower and better than before intervention (P < 0.01). Patient satisfaction was greatly improved, with a statistically significant difference (P < 0.05). Conclusion: The chronic disease management intervention model led by specialized nurses is conducive to improving the psychological state and nutritional status of dialysis patients, enhancing the adequacy of dialysis for patients, reducing the incidence of related complications, and ultimately achieving the purpose of improving the quality of life of patients, which has significant clinical value.
Perfil socioeconômico e o esforço de pesca na captura do caranguejo-uçá em unidades de conservação do Delta do Parnaíba (Brasil)
Authors: Crespo Maria de Fátima Vieira , Gomes Jaíra Maria Alcobaça , Da Silva Regina Olilveira
Published: June 2024

Ucides cordatus (Linnaeus, 1963) é a principal espécie de caranguejo encontrada nos manguezais brasileiros. No Nordeste do Brasil nota-se a diminuição desse recurso pesqueiro devido ao alto nível de exploração. Considerada a implementação da IN MPA N.09/2013, estudou-se o perfil socioeconômico dos coletores e o esforço de pesca na captura dos caranguejos nas unidades de conservação de uso sustentável do Delta do rio Parnaíba, nos estados do Piauí e Maranhão. A pesquisa-ação e métodos participativos nortearam os estudos. Percorreu-se 15 comunidades, quatro no interior da Reserva Extrativista e 11 no entorno de setembro de 2015 a outubro de 2016, por meio de oficinas participativas e aplicação de questionários estruturados a 66 extrativistas, além de observação direta e medida da captura por unidade de esforço (CPUE). A cata do caranguejo é um trabalho exclusivamente masculino, realizado na maré baixa e que exige grande esforço físico do extrativista, tanto que 61,4% dos ativos possuem até 35 anos de idade. A maioria dos catadores de caranguejos (56,4%) não sabem ler ou escrever dificultando a negociação frente aos patrões e intermediários, embora detenham profundo conhecimento sobre o ambiente e a ecologia, desenvolvidos pelo “fazer e saber fazer” de suas atividades e relacionadas ao ambiente vivido e construído. A desorganização e desgovernança desses atores propicia diferença de preços entre as comunidades, resultado do poder de mercado dos intermediários. Destarte, os extrativistas são donos de sua força de trabalho e de seus saberes tradicionais, mas não tem propriedade sobre o produto oriundo desse trabalho e do seu conhecimento
Poverty in the History of Economic Thought: From Mercantilism to Neoclassical Economics.
Authors: Romero Gustavo
Published: June 2024

Resenha de livro.
A natureza ortodoxa ou heterodoxa da política econômica em Angola: o período 2004-2018
Authors: Ambrósio Heitor Simão , Mollo Maria de Lourdes Rollemberg
Published: June 2024

Este artigo discute a ortodoxia e a heterodoxia da política econômica, tanto do ponto de vista teórico, quanto da análise empírica das políticas monetária e fiscal de Angola no período 2004-2018. Nas primeiras seções, se estabelece o critério de classificação das teorias econômicas como ortodoxas e heterodoxas, e se descrevem as principais ideias da ortodoxia econômica, em termos de papel da moeda e do Estado. Em seguida, se faz o mesmo processo para duas heterodoxias, a pós-keynesiana e a marxista. Finalmente, e com base na descrição prévia, analisa-se a evolução das políticas monetária e fiscal de Angola, com relação aos problemas de crescimento do produto e redução do desemprego e da inflação, quanto ao seu caráter ortodoxo ou heterodoxo.
Selective non–operative treatment of gunshot penetrating abdominal wounds
Authors: Khoroshun E. M. , Lurin I. A. , Makarov V. V. , Panasenko S. I. , Negoduyko V. V. , Shipilov S. A. , Bunin Y. V. , Salyutin R. V.
Published: June 2024

Objective. To analyse own experience and determine the feasibility and tactics of selective non–operative treatment of gunshot penetrating abdominal wounds.
Materials and methods. The study involved 74 servicemen (all men) with gunshot shrapnel penetrating abdominal wounds, who were divided into two groups: the main group – 26 (35.2% ± 0.2%) wounded who received non–surgical treatment, and the control group – 48 (64.8% ± 0.3%) wounded who received surgical treatment in the form of diagnostic laparotomy or laparoscopy. Non–surgical treatment included pain relief, antibiotic prophylaxis, tetanus toxoid administration and dressings.
Results. In general, selective nonoperative treatment of gunshot penetrating abdominal wounds was used in 1% of the wounded. Isolated abdominal wounds were present in 32 (43.2% ± 0.2%) and thoracoabdominal wounds in 42 (56.8% ± 0.3%) patients. In terms of the number of foreign bodies, wounds were single in 66 (89.2% ± 0.3%) and multiple (liver and retroperitoneal space) in 8 (10.8% ± 0.1%) patients. In the main group, there were no surgical interventions or complications, in the control group, 8 (16.7% ± 0.1%) diagnostic laparotomies and 40 (83.3% ± 0.3%) diagnostic laparoscopies were performed, and there were 2 (4.2% ± 0.1%) complications – seroma and pneumonia. The average treatment period was (5 ± 0.3) days in the main group and (8 ± 0.4) days in the control group.
Conclusions. Selective non–surgical treatment of gunshot penetrating abdominal wounds is indicated in haemodynamically stable patients without reduced level of consciousness and signs of peritonitis and intra–abdominal bleeding, abdominal pain syndrome with a follow–up period of 24 – 48 hours. The tactic of selective non–operative treatment of gunshot penetrating abdominal wounds is advisable mainly in case of damage to parenchymal organs. This tactic can be used in the presence of expert–class equipment, experienced specialists in the conditions of the third level of medical care and interaction between the second and third levels of medical care.
Features of the neutrophil granulocyte system in patients with common scalp defects
Authors: Hindych O. A. , Tumasova K. P.
Published: June 2024

Objective. To identify the dynamics of changes in the structure of the neutrophil granulocyte system in patients with extensive scalp defects before and after their surgical closure.
Materials and methods. A computer morphometric analysis of the quantitative and qualitative characteristics of neutrophilic granulocytes of patients with common scalp defects who were treated at the Department of Microvascular Plastic and Reconstructive Surgery of the Shalimov National Scientific Centre of Surgery and Transplantation from 2017 to 2023. The main group included 15 patients with widespread defects of the soft tissues of the scalp in the I – II stage of the wound process (10) and arteriovenous angiodysplasias in the III stage according to Schobinger (5). The control group consisted of 15 volunteers without pathology. The structure features (optical cytoplasmic density in units, which indicates the presence of bactericidal potential, and cell area in μm², which indicates the level of activation) of peripheral blood neutrophil granulocytes before and after surgical closure of the defect were studied.
Results. Before the surgical intervention, a pronounced polymorphism was detected, which meant a functional failure of the neutrophil granulocyte system. After surgery and healing of the defect, excessive polymorphism of the neutrophil granulocyte system was not detected in patients.
Conclusions. The assessment of the degree of cellular polymorphism of neutrophil granulocytes determines the diagnostic efficiency of the study and makes it possible to identify and predict the development of local inflammation and infectious complications in patients with scalp defects.
Analysis of Inflammatory Markers and Electroencephalogram Findings in Pediatric Patients with COVID-19: A Single-Center Study in Korea
Authors: Lee Sunho , Kim Kyung-Ran , Koo Chungmo
Published: June 2024

Purpose: The Omicron variant wave spread rapidly from February 2022 in South Korea following the initial management of the coronavirus disease 2019 (COVID-19) outbreak. This study examined electroencephalogram (EEG) findings and serological inflammatory markers in pediatric patients with COVID-19 (Omicron variant).Methods: We retrospectively reviewed the medical records of 41 patients who presented at Gyeongsang National University Changwon Hospital between March and May 2022 and were diagnosed with COVID-19. All serological tests were performed within 24 hours of fever or seizure onset. Results: The median patient age was 3.6 years (range, 0.08 to 14.00), and the average hospital stay was 3.7 days (range, 1.0 to 7.0). Interleukin-6 (IL-6) levels were elevated above the normal range in all patients (median, 43.18 pg/mL; range, 7.0 to 190.0) and were higher among those who experienced seizures. Of the 41 total patients, 17 (41.5%; mean age, 5.4 years) visited the clinic for seizure. Three patients experienced prolonged seizures (lasting longer than 30 minutes) and received intravenous lorazepam, while eight presented with complex febrile seizures. Nine patients underwent EEG, of whom five exhibited abnormal initial findings. Linear regression demonstrated correlations between prolonged seizure duration and both serum IL-6 level and blood lymphocyte count.Conclusion: Numerous serological markers associated with the immune cascade were found to be elevated in children with COVID-19. Nevertheless, febrile seizures represent a relatively common neurological presentation among pediatric patients infected with Omicron variants. Consequently, COVID-19 infection exhibits both familiar and distinct characteristics regarding the mechanisms inducing seizures and fever in children.
Revolutionizing onion preservation: A novel aerated storage approach
Authors: Muhit Abdullah-Al , Islam Md. Hamidul , Husna Asmaul , Zereen Ismot
Published: June 2024

The second goal of sustainable development is ending hunger, achieving food security improving nutrition, and promoting sustainable agriculture. Improved storage system is a part of sustainable agriculture. This research aimed to design and develop an aerated storage system for onions and examined the extent of losses to assess the efficacy of the storage system. Unseasonal rainfall and adequate storage facilities result in quick sales and spoilage of onions. A huge amount of onion is damaged due to a lack of proper post-harvest actions like storage, transportation, temperature control, and humidity control in our country. In this study, 40 kg of onion inside the storage and 10 kilograms outside the storage were stored for four weeks from 12 October to 8 November to observe parameters like percentage of moisture loss, sprouting, deterioration, and marketable onion. Temperature as well as relative humidity was observed throughout storage. After completing the research, it was found that the appropriate temperature was 27˚C with 83% relative humidity resulting in minimum losses throughout four weeks of storage period. It was also observed that marketable onion bulbs for aerated storage systems was 97.536% on the other hand marketable onion bulbs for natural or open storage systems was 91.629% which was less than aerated storage systems. So, the aerated storage system is more effective for storing the onion than the natural or open storage system. Small-scale farmers will be benefited and the supply chain management will be maintained using this storage system. Additionally, stakeholders and families will benefit from reduced onion damage percentages when utilizing this storage solution.
Assessing drought tolerance in advance wheat genotypes using stress tolerance indices
Authors: Rijal Ramesh Babu , Bashyal Pukar , Yadav Dil Raj , Upadhyay Koshraj , Pant Khem Raj , Adhikari Nav Raj
Published: June 2024

Wheat, an important crop of Nepal, is significantly affected by drought, leading to severe yield losses. Thus, an experiment was conducted to assess effect of drought on wheat traits and to identify drought resilient genotypes comparing stress tolerance indices. Altogether seventy-two genotypes including checks were evaluated under drought and non-stress condition in an alpha-lattice design with two replications at the research block of National Rice Research Program, Hardinath, Nepal during winter of 2019/20. Analysis of variance revealed significant genotypic differences (p<0.01) in traits such as days to heading, anthesis, and maturity, plant height, flag leaf area, spike length, grains per spike, 1000-grain weight, and grain yield under both conditions. The combined analysis of variance showed that genotype, environment, and their interaction significantly influenced most traits. The environment was the dominant factor, accounting for 86.2% of the variation in grain yield, followed by genotype (9.5%) and genotype-environment interaction (4.3%). Among the nine quantitative traits assessed, grain yield was most severely affected due to drought, experiencing a substantial reduction of 63%. To assess drought tolerance, six indices (TOL, SSI, MP, GMP, HMP, and STI) were calculated based on grain yield data. Most indices identified genotypes NL1373, NL1308, NL1407, BL4868, and BL4947 as highly drought-tolerant. Among the indices, MP, STI, and GMP were the most reliable for measuring stress tolerance due to their strong positive correlation with yield under both conditions. These identified genotypes are promising candidates for breeding programs aimed at developing drought-resilient wheat varieties, thereby enhancing food security in drought-affected regions.
Dominance of Bactrocera dorsalis Hendel on Ceratitis cosyra Walker (Diptera: Tephritidae) in orchards in Bujumbura, Burundi
Authors: Ndayizeye Liévin , Odette Manirakiza , Nduwarugira Déogratias , Sibomana Claver , Dieudonné Ntakirutimana
Published: June 2024

The aim of this study was to investigate the population fluctuations of Bactrocera dorsalis and Ceratitis cosyra in mango, citrus, and mixed orchards in Bujumbura city. Data was collected from six sites from December 2018 and December 2019 using trapping methodology. Two attractants (methyeugenol and terpinyl acetate), insecticide (dichlorvos DDVP 70%) and tephri traps were employed to attract and kill flies. The results indicate that B. dorsalis was more abundant in all sites (97.91%) than C. cosyra (2.09%). Fluctuation peaks for B. dorsalis were observed in April, October and December. A significant difference was noted in the monthly catches of both species (p<0.05). For C. cosyra, significant differences were observed in catches across all sites (p<0.05), whereas for B. dorsalis no such differences were found (p>0.05). The population fluctuations of B. dorsalis were observed during the maturation of mango and citrus fruits. B. dorsalis dominated in all sites.
Sheath Blight of rice: A review of host plant interaction and disease management
Authors: G.C. Ganesh , Roka Puja
Published: June 2024

The devastating pathogen Rhizoctonia solani, which is responsible for significant quality and production losses worldwide, is discussed in this review article along with the symptoms, disease cycle, epidemiology which causes sheath blight disease in rice. R. solani Kuhn, poses a significant threat to tropical Asia's rice production, potentially reducing grain yield by 50%. The article also emphasises the numerous management techniques, such as cultural, biological, and chemical controls. It is a severe production bottleneck in high yielding rice varieties under intensive rice production techniques, monoculture methods, a dense canopy, and extensive nitrogen management. Disease propagation in fields is influenced by air temperature, moisture content, and leaf wetness, with 16-25 C temperature range and 90% humidity favoring growth. Vertical and horizontal spread are influenced by these factors. The article provides comprehensive insight on host plant interaction of pathogen R. solani.
Pengaruh Gaya Kepemimpinan Kepala Puskesmas Terhadap Kinerja Tenaga Kesehatan Di Puskesmas Polewali, Kabupaten Polewali Mandar
Authors: Anwar Usman , Ali Ahmad
Published: June 2024

“Pengaruh Gaya Kepemimpinan Kepala Puskesmas Terhadap Kinerja Tenaga Kesehatan Di Puskesmas Polewali, Kabupaten Polewali Mandar”. Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh gaya kepemimpinan kepala Puskesmas terhadap kinerja tenaga kesehatan di Puskesmas Polewali, Kabupaten Polewali Mandar. Populasi dalam penelitian ini adalah seluruh tenaga kesehatan Puskesmas Polewali yaitu sebanyak 96 orang. Adapun jumlah sampel yang digunakan sebanyak 56 orang dengan Teknik random sampling. Pengumpulan data dilakukan dengan menggunakan metode angket (kuesioner). Teknik analisis data yang digunakan adalah Analisis Regresi Linear Sederhana dengan menggunakan SPSS 20. Berdasarkan hasil analisis dapat simpulkan bahwa Gaya Kepemimpinan Kepala Puskesmas berpengaruh positif dan signifikan terhadap Kinerja Tenaga Kesehatan di Puskesmas Polewali, Kabupaten Polewali Mandar, yang berarti gaya kepemimpinan yang baik tentunya akan memberikan peningkatan kualitas serta kuantitas hasil kinerja tenaga kesehatannya yang kemudian memberikan kemajuan bagi Puskesmas Polewali, Kabupaten Polewali Mandar.
ANALISIS SUMBER DAN PENGGUNAAN MODAL KERJA DALAM MENINGKATKAN LIKUIDITAS PERUSAHAAN PADA PT. INDOFOOD SUKSES MAKMUR
Authors: Gassing A Ahmad Burhan , Kurniawan Agung Widhi , Budiyanti Hety
Published: June 2024

Penelitian ini bertujuan untuk mengetahui bagaimana sumber dan penggunaan modal kerja untuk meningkatkan likuiditas PT Indofood Sukses Makmur Tbk. Sampel dalam penelitian ini yaitu dari laporan keuangan perusahaan dari tahun 2011-2020. Metode pengumpulan data menggunakan metode kualitiatif dengan menganalisis laporan keuangan perusahaan. Teknik analisis data yang digunakan adalah analisis sumber dan penggunaan modal kerja dan analisis rasio likuiditas. Hasil penelitian menunjukkan bahwa sumber dan penggunaan modal kerja yang diterapkan oleh PT. Indofood Sukses Makmur Tbk selama periode 2011-2020 dapat dikatakan cukup efektif. Kecukupan keefektifan pengelolaan modal kerja dapat dilihat dari rasio likuiditasnya, khususnya pada rasio tetap (Current Ratio) perusahaan yang masih dalam kondisi yang cukup baik. Hal ini dapat dilihat pada rata-rata nilai rasio lancar perusahaan dari tahun 2011-2020 sebesar 159%, akan tetapi selama periode ini perusahaan lebih meningkatkan penggunaan modal kerjanya yang menyebabkan rasio likuiditasnya hanya dalam keadaan cukup baik. Maka dari itu perusahaan mesti meningkatkan sumber modal kerja dibandingkan dengan penggunaan modal kerja dalam menjalankan operasi perusahaan agar dapat meningkatkan tingkat likuiditas perusahaan.
Analisis Covid-19 Penghambat Ekspor Impor dan Bisnis Antara Indonesia - Cina
Authors: Yulianty Neng Novy , Solihah Destyani Mariah , Rahman Noor , Cahyani Dini , Rizki Ivan Muhammad , Guntari Sheirany , Kresnayanti Ari , Firmansyah Ricky
Published: June 2024

Ekspor dan Impor merupakan kegiatan ekonomi  kanca perdagangan internasional yang ada di dalam suatu negara untuk menggerakan pertumbuhan  ekonomi dan sumber pendapatan suatu negara. Namun,  apa yang akan terjadi apabila sumber pendapatan dan kebutuhan suatu Negara terhambat karena adanya wabah penyakit mematikan yang hampir seluruh Negara terkena dampaknya dengan jangka waktu penyembuhan yang relatif lama, yang dapat menghambat proses kerjasama internasional , yang membuat nilai Ekspor dan Impor suatu Negara mengalami kenaikan dan penurunan . Maka dari itu dilakukan suatu Penelitian yang  bertujuan untuk mengetahui Analisis Dampak pandemi Covid-19 Terhadap pertumbuhan nilai Ekspor dan Impor Indonesia  -  Cina sejak  sebelum adanya pandemi  Covid-19, pada masa pandemi dan masa setelah pandemi , serta mengamati perdagangan Internasional pada kedua negara dengan cara mengumpulkan data ekspor-impor dari hubungan billateral Indonesia-Cina. Penelitian ini menggunakan metode studi literatur dengan pengumpulan data statistik  yang telah terhitung secara akurat dari beberapa pengamat ekonomi dunia, dan Badan Pusat Statistik (BPS) tahun 2022 . Hasil data yang diperoleh bahwasannya tidak ada perubahan yang signifikan terhadap kegiatan Ekspor-Impor antara Indonesia-China sebelum dan sesudah terjadinya pandemi  Covid-19 Yaitu pada tahun 2020, namun hanya  terjadi sedikit penurunan diawal tahun 2020 hanya sebentar yaitu dibulan Februari, dan mulai mengalami kenaikan di bulan Maret karena kebutuhan akan barang, bahan pokok dan infrastuktur yang tidak bisa di stop serta kerjasama yang erat antar keduanya yang saling mengisi kebutuhan satu sama lain.  Kata kunci :  Analisis, Covid-19, Dampak, Ekspor, Impor, Pertumbuhan
PENGARUH MOTIVASI KERJA TERHADAP KINERJA PEGAWAI PADA KANTOR DINAS PENANAMAN MODAL DAN PELAYANAN TERPADU SATU PINTU KABUPATEN LUWU UTARA
Authors: Syahruddin Athifah Nadya Putri , Ruma Zainal , Burhanuddin Burhanuddin , Hasbiah Siti , Natsir Uhud Darmawan
Published: June 2024

Abstrak. Penelitian ini bertujuan untuk mengetahui apakah Motivasi Kerja berpengaruh terhadap Kinerja Pegawai Dinas Penanaman Modal dan Pelayanan Terpadu Satu Pintu Kabupaten Luwu Utara. Populasi dalam penelitian ini adalah keseluruhan pegawai DPMPTS Luwu Utara berjumlah 44 pegawai. Sedangkan sampel dalam penelitian ini ditentukan dengan mengambil seluruh populasi sebagai sampel, sehingga sampel dalam penelitian ini yaitu 44 orang pegawai. Observasi, Kuesioner dan Dokumentasi merupakan metode pengumpulan data yang digunakan. Sedangkan Teknik analisis data yang digunakan adalah analisis kuantitatif dengan melakukan pengujian hipotesis menggunakan regresi linear sederhana. Hasil penelitian yaitu menunjukkan bahwa Motivasi Kerja memberikan pengaruh positif dan signifikan terhadap kinerja pegawai pada kantor DPMPTSP Kabupaten Luwu Utara, hal ini dibuktikan dengan perolehan nilai t tabel > t tabel (2,995 > 1,68107) dan nilai sig. < 0,05 (0,005 < 0,05) sehingga hipotesis dalam penelitian ini diterima.Kata kunci: Motivasi Kerja, Kinerja Pegawai.Abstract. This study aims to determine whether work motivation influences the performance of employees of the Investment and One-Stop Services Office in North Luwu Regency. The population in this study were all DPMPTS Luwu Utara employees totaling 44 employees. While the sample in this study was determined by taking the entire population as a sample, so that the sample in this study was 44 employees. Observation, Questionnaire and Documentation are the data collection methods used. While the data analysis technique used is quantitative analysis by testing the hypothesis using simple linear regression. The results of the study show that work motivation has a positive and significant influence on employee performance at the DPMPTSP office of North Luwu Regency, this is evidenced by the acquisition of t table > t table (2.995 > 1.68107) and sig. <0.05 (0.005 <0.05) so that the hypothesis in this study is accepted. Keyword: Work Motivation, Employee Performance.
PENERAPAN METODE CSI (CUSTOMER SATISFACTION INDEX) DAN IPA (IMPORTANCE PERFORMANCE ANALYSIS) PADA TINGKAT KEPUASAN PELANGGAN MIXUE (STUDI KASUS MAHASISWA UIN RADEN MAS SAID SURAKARTA)
Authors: Hayuningtyas Widya Galuh , Ziadah Tsai'un Nur , Shofiana Umu Salma , Susilowati Heni , Mu'tashim Muhammad Faris , Yoga Ika
Published: June 2024

Era persaingan bisnis saat ini yang semakin ketat, kepuasan pelanggan menjadi faktor krusial yang dapat menentukan keberhasilan suatu perusahaan. Peningkatan kepuasan pelanggan menjadi fokus utama bagi perusahaan Mixue, yang beroperasi di industri pelayanan. Meskipun sejauh ini pendekatan pemasaran Mixue sangat baik dan efektif, tidak ada jaminan bahwa pertumbuhannya akan berlanjut di masa mendatang. Berdasarkan masalah ini, peneliti bermaksud untuk menggunakan metodologi CSI dan IPA untuk mempelajari kebahagiaan pelanggan Mixue dan menganalisis temuan untuk menentukan area yang perlu ditingkatkan untuk meningkatkan kepuasan pelanggan. Hasil penelitian menunjukkan bahwa tingkat kepuasan konsumen berdasarkan analisis CSI adalah sebesar 78,87% yang menunjukkan indeks kepuasan pelanggan berada pada kategori puas. Pada pengujian dalam metode IPA terdapat 1 atribut yang masuk ke dalam kuadran 1 yang artinya ada 1 atribut pelayanan yang belum maksimal.
PENGARUH LINGKUNGAN KERJA TERHADAP PRESTASI KERJA KARYAWAN PADA PT KONTAK PERKASA FUTURE CABANG MAKASSAR
Authors: Putri Ainin Alvyana , Kurniawan Agung Widhi , Sahabuddin Romansyah
Published: June 2024

Abstrak. “Pengaruh Lingkungan Kerja Terhadap Prestasi Kerja Karyawan Pada PT Kontak Perkasa Future Cabang Makassar”. Penelitian ini untuk mengetahui pengaruh Pengaruh Lingkungan Kerja Terhadap Prestasi Kerja Karyawan Pada PT. Kontak Perkasa Future Cabang Makassar. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan deskriptif dan merupakan penelitian populasi. Sampel dalam penelitian ini adalah keseluruhan karyawan Pada PT. Kontak Perkasa Future Cabang Makassar. Uji hipotesis dalam penelitian ini menggunakan uji regresi linear sederhana dan mendapatkan hasil yaitu: Berdasarkan hasil uji hipotesis dengan menggunakan uji analisis regresi linear sederhana menunjukkan variabel lingkungan kerja secara parsial berpengaruh terhadap prestasi kerja karyawan Pada PT. Kontak Perkasa Future Cabang Makassar.Kata kunci: Lingkungan Kerja, Prestasi KerjaAbstract. “The influence of the work environment on employee work performance at the PT. Kontak Perkasa Future Cabang Makassar”. This study aims to determine whether there is an influence of the work environment on employee work performance at the PT. Kontak Perkasa Future Cabang Makassar. The research employs a quantitative approach with a descriptive method and constitutes a population study. The sample for this research comprises the entire workforce of 44 individual at the PT. Kontak Perkasa Future Cabang Makassar. Hypothesis testing in this study employs simple linear regression analysis, yielding the following outcomes: The results of the hypothesis testing also indicate that the work environment has a partial influence on employee work performance at the PT. Kontak Perkasa Future Cabang Makassar.Keyword: Work Environment, Work Performance
Assessment of weed species composition of Cabbage family plants (Brassicaceae) of ruderal and segetal habitats of the Ussuriysk urban district of the Primorsky Territory
Authors: Fedina L. A. , Markova T. O. , Maslov M. V.
Published: June 2024

The data on the species composition of weeds from the Cabbage family (Brassicaceae) that grow stably in the territory of the Ussuriysk urban district of the Primorsky Territory and dominate in agrocenoses are given in the article. Objectives of the study are: to summarize data on the most widespread (background) plant species of natural and adventive flora of the Cabbage family of ruderal and segetal habitats of the Ussuriysk urban district of the Primorsky Territory; to note the species listed in the "Black Book of Flora of the Far East" and growing within the limits of the urban district; to cite the species composition of herbaceous plants of the Cabbage family found in the Ussuriysky Nature Reserve. Field studies were conducted using the traditional route-reconnaissance method in 2010–2023. Phenological observations, geobotanical descriptions of identified habitats, collection, identification of herbarium material and photographing of objects from growing sites were carried out. Of the 23 species of Brassicaceae cited in the paper, ten are invasive in the ecosystems of the Far Eastern Federal District: Armoracia rusticana Gaertn., Mey. et Scherb., Berteroa incana (L.) DC., Brassica juncea (L.) Czern., Bunias orientalis L., Capsella bursa-pastoris (L.) Medik., Hesperis matronalis L., Lepidium densiflorum Schrad., Thlaspi arvense L., Turritis glabra L., Velarum officinale (L.) Reichenb. Most of them, with the exception of B. juncea, C. bursa-pastoris and Th. arvense, are classified as plants that do not cause significant damage at this stage of development. Ruderal habitats are also sites of biodiversity conservation. In the V.L. Komarov Ussuriysky Nature Reserve, 16 species of Cabbage, of which Barbarea orthoceras, B. incana, and Th. arvense are segetal, were identified on the territory of the Ussuriysk Urban District.
The system of images in Romanian-Moldovan folklore (based on the fairy tales by M. Eminescu and I. Creangă)
Authors: Burchanova A.
Published: June 2024

The article deals with the system of images in the magic fairy tales by M. Eminescu and I. Creangă. The research purpose is to determine the invariant features of the characters in Romanian-Moldovan folklore, to contrast the authors’ images of the characters with their prototypes and to compare the systems of images of both M. Eminescu and I. Creangă. The nominative approach allows us to find out how this specificity is manifested in the fairy tale texts through the names of various characters. The article covers detailed descriptions of Romanian-Moldovan magic fairy tale personages. These include positive characters, such as Făt-Frumos and Ileana Cosânzeana, as well as villains, for instance, Muma Pădurii, Statupalmă-barbă-cot and Zmeul. The classification of characters is based on the V. Propp and E. Meletinsky approach to the magic fairy tale. The article studies primary and secondary nominations of magic fairy tale personages and determines their stylistic, national and cultural potential. The study shows that the image of a character is formed through the use of nominations, whose semantics indicates certain attributes of the personage under consideration. These attributes include the character’s name, age, appearance, moral virtues, occupation and place of residence. Some nominations can have a number of positive meanings and play a pivotal role in shaping the ideal image of the protagonist. In magic fairy tales, antagonists are presented by means of nominations with negative semantics.