bluuebunny/crossref_metadata_2025 huggingface dataset:
O PAPEL DA SINALIZAÇÃO DO FGFR3 NA ACONDROPLASIA: REVISÃO SISTEMÁTICA
Authors: Neto Eclésio Batista de Oliveira
Published: January 2022

Introdução: A acondroplasia é a forma mais comum de displasia óssea ligada ao nanismo desproporcional em humanos. Sendo causada por mutações no gene FGFR3, localizado no braço pequeno (P) do 4º cromossomo autossômico, no lócus gênico p16. 3 (4p16.3). A mutação mais comum (p.Gly380Arg) ocorre no 380º códon desse gene, sendo classificada como uma mutação pontual com perda de sentido, onde há a substituição do nucleotídeo monofosfato de adenosina pelo monofosfato de guanosina. Essa mudança acaba alterando o aminoácido codificado por aquele códon (AGG-Arginina) para o aminoácido Glicina (GGG), impactando na estrutura final da proteína conhecida como FGFR3 (fibroblast growth factor receptor 3). A mutação faz com que as proteínas FGFR3 tenham uma hiperatividade anormal, que induz o fechamento da lâmina epifisial nos ossos dos membros inferiores e superiores. Objetivo: Revisar o papel da sinalização do FGFR3 na Acondroplasia. Material e métodos: Foi realizada uma revisão bibliográfica na base de dados BVS (Biblioteca Virtual em Saúde) e PUBMED com os descritores " Receptor, Fibroblast Growth Factor, Type 3 " e " Achondroplasia”, com o operador AND. Os critérios de inclusão foram (1) textos completos condizentes com o tema e objetivos do trabalho; (2) em inglês, espanhol e português; (3) publicados nos últimos 5 anos. Foram encontrados 67 estudos, após a aplicação dos critérios de inclusão e exclusão, foram mantidos e analisados 32 estudos. Resultados: Os artigos revisados enfatizam que os fatores de crescimento de fibroblasto (FGFs) atuam se ligando com alta afinidade ao FGFR3 na superfície celular, induzindo a dimerização de duas unidades de FGFR3, em seguida o dímero passa por uma autofosforilação em seu domínio intracelular, através da ação das unidades de tirosina quinase (T1 e T2) levando às sinalizações STAT1 e MAKP, que atuam inibindo a proliferação e diferenciação dos condrócitos na lâmina epifisária, resultando na diminuição da lâmina e consequente diminuição do alongamento ósseo. Conclusão: A atuação do receptor (FGFR3) e seus agonistas é muito importante, pois sem essa regulação nossos ossos iriam crescer demais, nos levando a desenvolver problemas relacionados ao gigantismo. No entanto, sua hiperativação está relacionada à condições como a acondroplasia.
Vorfreude aufs nasse Element
Authors: Heumer Wolfgang
Published: January 2022

Wassersport: Während die Winterkälte uns umschließt, machen wir uns warme Gedanken an den Urlaub über und unter Wasser. Technische Highlights gestalten das Vergnügen noch vergnüglicher. Von Wolfgang Heumer
Gustavo Gusto erwägt Börsengang
Authors: Sachsenröder Delphine
Published: January 2022

Das Tiefkühlpizza-Startup Franco Fresco bereitet einen Börsengang vor: Das Unternehmen hinter der Marke Gustavo Gusto schafft mit einer neuen Struktur die Voraussetzungen für eine mögliche Aktiennotierung, wie Gründer Christoph Schramm sagt. Er hegt zudem Wachstumspläne für das Ausland.
Hornbach geht das Projekt Zukunft an
Authors: Hofmann Janine , Stockburger Manfred
Published: January 2022

Albrecht Hornbach stellt die Weichen für die Zukunft des Baumarktkonzerns. Während sich der Kapitalmarkt mit dem laufenden Delisting der Baumarkt AG befasst, sichert der Konzernchef den Einfluss der Familie für die nächsten Generationen.
Metro peilt Umsatz von 40 Mrd. Euro an
Authors: Schulz Hans-Jürgen , Müller Annette
Published: January 2022

Metro will aus der Wachstumsdelle raus: CEO Steffen Greubel kündigt ein Maßnahmenpaket an, erhöht die Investitionen und will bis 2030 den Gesamtnettoumsatz um 15 Mrd. Euro steigern.
Verdi erhöht Einfluss auf Rewe Group
Authors: Tewes Werner
Published: January 2022

Im Aufsichtsrat der Rewe Group verschieben sich im Arbeitnehmerlager die Machtverhältnisse: Verdi darf künftig drei Kontrolleure ins Gremium entsenden. Bei den anstehenden Wahlen fallen der Gewerkschaft die zwei Sitze zu, die bislang noch die Konkurrenzorganisation DHV innehat.
Oberlandesgericht Düsseldorf rehabilitiert Christoph Barre
Authors: Bender Hanno
Published: January 2022

Das Bundeskartellamt hat im Kölsch-Kartell Beweise falsch gewürdigt und die Bußgelder gegen die Brauereien Früh, Gaffel und Erzquell auf zweifelhafte Settlement-Erklärungen gestützt. Zu diesem Ergebnis kommt das OLG Düsseldorf in seinem Urteil.
Kaum noch Spielraum
Authors: Hebben Miriam
Published: January 2022

Die Industrie sieht sich einer zunehmenden Nachfragemacht des Handels ausgesetzt. Die Abhängigkeit steigt, Auswege gebe es kaum, unlautere Mittel dagegen viele. Miriam Hebben
Prinzip Lego statt Playmobil
Authors:   Loderhose., Birgitt
Published: January 2022

Commercetools hat in den letzten zwölf Monaten den Umsatz mit seiner Onlineshop-Software verdoppelt, sagt Gründer Dirk Hoerig, ohne Zahlen zu nennen. Im Interview erklärt er, was die Kunden Porsche und Rewe gemeinsam haben und wo er 2022 hin will.
Facebook verspricht die größte Fangemeinde
Authors: Rentz Ingo
Published: January 2022

Branding betreiben, Sonderangebote posten, sich mit Wettbewerbern kabbeln: Ohne soziale Netzwerke kommen Lebensmitteleinzelhändler nicht mehr aus. Doch wie schlagen sich Edeka, Aldi, Lidl und Co dabei? Web-Netz hat die Performance der Konzerne im Social-Web untersucht.
Discounter verkürzen Abstand zum Vollsortiment
Authors: Konrad Jörg
Published: January 2022

Das Geschäft im LEH läuft wegen der Pandemie weiterhin gut. Der LEH konnte 2021 die hohen Umsatzzuwächse aus dem ersten Corona-Jahr im zweiten Jahr behaupten. Die Food-Vollsortimenter lagen laut dem jüngsten „Consumer-Index“ der GfK in jedem Monat über den Discountern.
“Şeytan Tüyü”: Düzensiz Bir Göçmenin Almanya’da Hayatta Kalma Stratejileri
Authors: ÇİÇEK Ayşe
Published: January 2022

Türk edebiyatında Almanya’ya göçü konu edinen pek çok önemli yazın bulunmaktadır. Bunlar içerisinde Haldun Taner’in “Şeytan Tüyü” hikâyesi düzensiz bir göçmenin Almanya’daki gündelik mücadelesini ironik ve mizahi bir üslupla ele almaktadır. Bu çalışmada “Şeytan Tüyü” hikâyesinin kahramanı düzensiz göçmen Ökkeş’in toplumdaki iktidar ilişkilerine karşı hangi şekillerde direndiği analiz edilmiştir. Göçmen bireyin hayatta kalma stratejileri Scott’ın gündelik direniş biçimleri ve de Certeau’nun taktik kavramı çerçevesinde ortaya konulmaktadır. Hikâyedeki söylemler analiz edilirken yazarın diğer yazılarından, hikâyeyle ilgili basındaki haberlerden, yazarla yapılan bir söyleşiden ve yazarın hayatını konu alan belgesel ve biyografilerden yararlanılmıştır. Göçmenlerin iktidar yapıları karşısında zafer kazanmasına olanak sağlayan taktikler; göstermelik itaat, boşluklardan yararlanma, kurnazlık, anonimlik ve kılık değiştirme olarak karşımıza çıkmaktadır. Hikâyenin merkezinde yer alan direniş biçimi göçmen bireyin anonimlik politikasıdır. Sıradan birey bu taktikler sayesinde riskten uzak bir şekilde ev sahibi ülkede yaşamını sürdürmekte ve kendisine dayatılan iktidarı el altından yıkmaktadır.
The Effects of the Capitalist System on Individuals: The Fool
Authors: IŞIK Sevcan
Published: January 2022

This paper aims to analyze the effects of the capitalist system on individuals belonging to the working class in the Fool (1975) by Edward Bond. In the play, the capitalist system is portrayed as cruel because it deprives the individual from their basic needs such as dignity or freedom and as unequal because it makes a class superior to another one. For instance, while working class people cannot even have bread to eat, the parson has a silver pen and gold in his pocket. This wide gap between the two classes brings about inequality, class conflict and dehumanization observed in a capitalist society. This explains the reason why the individuals in the play feel alienated and ineffective. In addition, church and hospital as representatives of social institutions in society will be studied to reflect the fact that how they preserve the interests of the ruling class. The paper will conclude that individuals in the play will survive either by resorting to violence as in the case of Darkie, complying with system as in the case of Patty or revolting against the system as in the case of Clare.
Kütahya Çiniciliğinin Ekonomik ve Sosyokültürel Bakımdan Değerlendirilmesi
Authors: KILIÇ Ramazan , BAHÇE Ezgi
Published: January 2022

Yüzyıllar öncesine dayanan çinicilik, Kütahya için özel önemi olan bir sektördür. Çinicilik şehrin ekonomisine olan katkısının yanı sıra sanatsal boyutuyla sosyokültürel olarak da şehre değer katmaktadır. Yıllar içerisinde zaman zaman durgunluk yaşamasına rağmen, kendini yenileyerek ve geliştirerek canlanan Kütahya çiniciliği, tarihte kendine önemli bir yer edinmiştir. Günümüzde hala canlılığını koruyan ve Kütahya ekonomisinin önemli bir bölümünü oluşturan çinicilik sektörü; çinicilik sektöründe üretim yapan işletmelerin karşılaştığı birtakım ekonomik sorunlar, çini sanatının tanıtımının yeterli düzeyde yapılmaması, kayıt dışı üretimin varlığı, çinicilikte markalaşmanın eksikliği ve sektörde yaşanan pazarlama sorunları nedeniyle gerektiği önemi görememektedir. Bu çalışmada Kütahya çiniciliğinin; tarih içerisindeki gelişimi ve günümüzdeki durumu ekonomik ve sosyokültürel yönden ele alınmıştır. Bu çerçevede çinicilik sektörünün ekonomik sorunları belirlenmiş, Kütahya çiniciliğinin hak ettiği değeri bulması ve şehre olan ekonomik katkısının gerçekleşen düzeyden fazla olmasının sağlanması için çözüm önerileri sunulmuştur.
Coming of Age: Migrant Economies and Social Policies in Germany
Authors: Hillmann Felicitas
Published: January 2022

This paper analyzes the policies for migrant economies as part of broader social and labor market in Germany. It points out that the current fragmented and contradictory policy action can be identified as an outcome of former ambiguities and the delegation of responsibilities within a complex governance grid. Accordingly, its focus is on the inter-related dynamics of policy interventions, knowledge production and the impact of migrant agency within cities. The paper gives a condensed overview on theory and background of migrant economies, pointing to de facto barriers that persist until today. It then concentrates on the way labor market policies in respect of migration were framed in public discourse. Its empirical focus is on the web of policies and instruments that have been directed towards migrant entrepreneurship. Here, in-built ambiguities of all actions are identified as a general feature of German labor market policies.
Derechos humanos y Fuerza Armada
Authors: Vargas Escolero Marcel
Published: January 2022

No hay resúmenes disponibles.

ECA Estudios Centroamericanos, Vol. 52, No. 588, 1997: 1011-1014.
¡Qué viva la democracia!
Authors: Montoya Aquiles
Published: January 2022

No hay resúmenes disponibles.

ECA Estudios Centroamericanos, Vol. 52, No. 588, 1997: 1015-1017.
Julio, septiembre, octubre, noviembre y diciembre de 1996
Authors: Editor El
Published: January 2022

No hay resúmenes disponibles.

ECA Estudios Centroamericanos, Vol. 52, No. 588, 1997: 1043-1060.
Posición de la FUNDE ante la coyuntura actual
Authors: Editor El
Published: January 2022

No hay resúmenes disponibles.

ECA Estudios Centroamericanos, Vol. 52, No. 588, 1997: 1061-1064.
The efficacy of homoeopathic similimum in the treatment of nocturnal enuresis in children between five and eighteen years who reside in children's homes
Authors:   , Bloch Michael
Published: January 2022

This study was intended to evaluate the efficacy of homoeopathic similimum in the treatment of nocturnal enuresis. It was part of a group research project, which explored the effectiveness of a homoeopathic complex (Cantharis vesicatoris 12ch, Equisetum hyemnale 12ch, Sarsaparilla 12ch, Staphisagria 12ch, Uva ursi 12ch) as well as Ilex paraguayensis 6x in the treatment of the above-mentioned disorder. The sample group consisted of children between the ages of five and eighteen living in various children's homes in Durban. Nocturnal enuresis is categorised into primary and secondary types. Primary nocturnal enuresis is the failure to achieve consistent dryness, whereas secondary nocturnal enuresis is the return of nocturnal incontinence after an extended period. For the purpose of this study this distinction was largely ignored, as homoeopathic treatment is not reliant on a detailed diagnosis for its efficacy. The children were however screened for chronic urinary tract infections as well as neurological and systemic causes of nocturnal enuresis. Each child received a full physical examination as well as an extensive homoeopathic interview. The aim of this was to exclude any clear aetiology as well as to glean I the information necessary to establish the homoeopathic similimum. The sample size for this trial was 32 children; sixteen received similimum and formed the treatment group, and a further sixteen received placebo and formed.
The relative efficacy of two varied chiropractic manipulative techniques in the treatment of mechanical upper thoracic and neck pain
Authors:   , Ritchie Bruce Andrew
Published: January 2022

The purpose of this study was to determine the effectiveness of the spinous push versus the transverse process contact rotary type adjustments in the treatment of sub-acute and chronic mechanical upper thoracic and neck pain. It was hypothesized that both adjustments, over a maximum of nine treatments with two treatments per week and a further four week follow-up period, would be effective in terms of improving the patients' cervical ranges of motion, vertebral pressure pain threshold levels and their perceptions of pain and disability. The study design was a randomized, un-blinded, un-controlled comparative group study with a sample population consisting of thirty consecutive patients (Ave. age 35.4 years; M:F 16: 14) suffering from joint dysfunction of the cervical or upper thoracic spine. Each group received one adjustment two times a week for a maximum of nine treatments. Soft tissue therapy was employed in each treatment as a pre-adjustment procedure. The objective data collected was goniometrically assessed cervical range of motion and algometrically assessed vertebral pressure pain thresholds. The subjective data was collected by means of the CMCC Neck Disability, the Short Form McGill Pain and the Numerical Pain Rating Scale-l0 1 Questionnaires.
The relative effect of proprioceptive neuromuscular facilitated stretching immediately after eccentric exercise vs proprioceptive neuromuscular facilitated stretching post delayed onset muscle soreness in healthy, sedentary male subjects
Authors:   , Schlebusch Helen Beverleigh
Published: January 2022

Delayed onset muscle soreness (DOMS) is muscular pain which ranges from mild discomfort to severe debilitating pain, caused by eccentric exercise. It generally sets in 12 - 24 hours after the causative activity and subsides within approximately seven days. The aim of this study was to determine whether proprioceptive neuromuscular facilitated (PNF) stretching immediately after eccentric exercise was more beneficial than PNF stretching 24 hours after eccentric exercise on the muscle pain experienced in DOMS. This study was a prospective, randomised clinical trial. Thirty healthy sedentary male participants were randomly selected to participate in the study by advertising in local newspapers and pamphlet distribution in Durban and its surrounding areas. The patients' ages ranged from 20 to 32 years of age. Subjective and objective readings were taken at the beginning and end of each visit, over the three-day study period. This was done with the numerical pain rating scale and the algometer force gauge, respectively. Baseline measurements were taken before any exercise or stretching at the initial visit. All participants then were asked to do squats until fatigue to induce delayed onset muscle soreness. III The participants were divided randomly into two groups, Group A and Group B. The former group underwent PNF stretching immediately after exercise and the latter group underwent PNF stretching twenty four hours after exercise. Both groups were asked to return for two subsequent days following the initial visit and they again underwent PNF stretching at each visit. Comparison was made between the individual patients' pain perception over time, as well as between each group. Descriptive analysis was done using frequency tables (reporting counts and percentages) for categorical variables and summary statistics (reporting mean, standard deviation and range), for quantitative variables. Baseline and demographic characteristics were compared between the two treatment groups using independent t-tests for quantitative variables and Pearson's chisquare tests for categorical variables. The treatment effect was assessed using repeated measures ANOVA testing. Statistical analysis revealed that there was no difference in the improvement of pain experienced between the two groups. However, Group B (PNF stretching 24 hours after exercise) appeared to improve at a greater rate than Group A (PNF stretching immediately after exercise). A larger study needs to be conducted in order to provide statistically relevant results.
The effect of differing clinical settings on chiropractic patients suffering from mechanical low back pain
Authors:   , Richardson Grant Walter
Published: January 2022

Each healing encounter, and every treatment, has specific and non-specific treatment effects. Non - specific effects, or placebo effects, are the benefits felt by the patients because of the nature of the healing encounter. Although difficult to quantify and control, a number of authors recognize that the non-specific component of management has an additive effect on the overall clinical outcome. It has been reported that due to the physical interaction and social nature of chiropractic, there is a strong non-specific component in the management process, but to what extent it facilitates in the healing encounter is unknown. It has also been shown that spinal manipulation has a clinical effect which exceeds that of placebo; therefore it is possible for its effect to be muted or amplified, depending on the presence or absence of non-specific effects. For the above reasons this study was conducted in an attempt to map the size of the nonspecific effect in the healing encounter by manipulating the practice setting in which the patients were treated. This was achieved using a prospective, randomised, comparative clinical experiment consisting of 60 individuals with Low Back Pain (LBP), selected by convenience sampling. Individuals were then divided into 2 groups of 30. The IV first group's treatment consisted of the standard diversified method of manipulation in a Clinical Research Setting, and the second group received the same treatment except the treatment took place in a Normal Practice Setting.
The effectiveness of combined spinal manipulation and patella mobilization compared to patella mobilization alone in the conservative management of patellofemoral pain syndrome
Authors:   , Stakes Neil Osmond
Published: January 2022

Purpose. Patellofemoral pain syndrome (PFPS) refers to a syndrome associated with the following signs and symptoms: anterior knee pain, inflammation, imbalance, instability, or any combination thereof (Wood 1998). The purpose of this investigation was to evaluate whether spinal manipulation, as an adjunct to patella mobilization, contributed significantly to the improvement of patients diagnosed with PFPS. A prospective trial using convenient sampling was implemented using the first 60 volunteers that met the requirements. These were randomly divided into two groups. Participants in group 2 received combined patella mobilization and spinal manipulative therapy, while those in group 1 received patella mobilization only. Each patient selected for the study was required to complete an informed consent form. The selected patients underwent a general medical case history, lower back and knee orthopaedic regional examinations. 8 clinical experiments were done: pain threshold (ALGI), pain tolerance (ALG2), the mean least pain experienced (NRS 1), the mean worst pain experienced (NRS2), the mean pain experienced (NRS3), pain quality (McGill), patellofemoral joint evaluation scale (PFJE) and a patient specific functional scale (PSFS). All were continuous variables except McGill, which was a categorical variable. For each clinical experiment, readings were taken 3 times, i.e. at the first, third and sixth consultations
Intervenir autrement dans les milieux autrement dans les milieux éducatifs : repenser les assises épistémologiques du développement de l'enfant
Authors: Auclair David
Published: January 2022

Durant les années 1920-30, Lev. S. Vygotskij (1896-1934) s’intéresse aux médiations sémiotiques de la vie mentale afin d’étudier le développement des fonctions psychiques, émotionnelles et physiques de l’enfant. À cheval entre la pédologie et la défectologie, passionné d’art, de philosophie et de littérature, il sépare judicieusement l’âge mental de l’âge scolaire, mais aussi les savoirs cliniques des réalités éducatives. Toujours d’actualité, bien que demeuré en chantiers de son vivant, le projet éducatif vygotskien insiste sur le caractère dialectique du développement. Si le courant organiciste peut prétendre que le « petit d’homme apprend toujours mieux les faits qu’il découvre plutôt que les principes qu’on lui impose » (Piaget, 1997), il en va tout autrement pour celles et ceux qui préconisent l’approche historico-culturelle vygotskienne.  Dans cet article, nous montrons que les interventions et les apprentissages varient historiquement en fonction des orientations épistémologiques, des contextes, mais aussi des méthodes préconisées pour régulariser et pour « performer » dans des cadres historiquement construits (signifiants). À l’école comme dans les familles, il s’avère impossible de se soustraire à l’obligation de privilégier les expériences appuyées sur des médiations culturelles, à la fois langagières et historiques. À l’instar de Vygotskij, nous pensons que les « acteurs significatifs » doivent privilégier le diagnostic pédagogique à l’aide d’interventions savamment orchestrées autour de la zone de développement proche (ZDP).
Lietuvos bibliotekininko profesijos transformacijos: profesionalumas ir kompetencijų ugdymas
Authors: Janavičienė Daiva
Published: January 2022

Straipsnio tikslas yra remiantis šiuolaikinio bibliotekininko profesionalumo samprata ir kokybiniu empiriniu tyrimu išanalizuoti Lietuvos viešųjų bibliotekų direkcijų atstovų suvokimą apie bibliotekininko profesijos transformacijas, bibliotekininko profesionalumą nurodančių kompetencijų kaitą, svarbiausias profesionalumo kliūtis ir iššūkius. Atliktas kokybinis (empirinis) tyrimas patvirtina teorines mokslininkų įžvalgas apie bibliotekininkų profesijos transformacijas ir su tuo susijusius iššūkius. Intensyviausi pokyčiai vyksta dėl sparčiai kintančių technologijų, tačiau Lietuvos bibliotekininkai susiduria ir su politinių pertvarkų, ekonominio vystymosi netolygumų, konkurencijos apraiškomis. Nors viešosios bibliotekos vis labiau imasi lyderystės bendruomenėse vaidmens, siekia geriau pažinti ir atitikti bendruomenės lūkesčius, pripažįsta turinčios nuolat tobulinti kompetencijas ir siekti profesionalumo. Jo kaitos kliūtys reiškiasi ne tik per asmens ribotumus (konservatyvumą, nepakankamą motyvaciją tobulėti ir kt.), bet ir per objektyviai patiriamą bendros bibliotekų politikos stoką, negebėjimą demonstruoti bendruomenei teikiamos naudos. Teminės analizės metodu gauta Lietuvos bibliotekininko profesionalumą žyminčių kompetencijų schema rodo, kad tyrimo dalyviai didžiąja dalimi profesionalumą suvokia per bendrąsias tradicines ir inovatyvias, kūrybiškumą bei orientaciją į lankytoją apibrėžiančias kompetencijas. Būtina sukurti profesijos išskirtinumą sudarančių žinių ir įgūdžių branduolį, kurį turėtų įgyti visi bibliotekose naujai įdarbinami asmenys, o dirbantys bibliotekininkai galėtų daryti karjerą savo srityje pagal visiems žinomą bendrą sąsają tarp įgyjamų kompetencijų ir pasiektų einant tam tikras pareigas rezultatų.
Knygų skaitymas gydo: apie projekto „Biblioterapijos taikymas bibliotekose“ įgyvendinimo veiklas Lietuvos viešosiose bibliotekose
Authors: Janavičienė Daiva
Published: January 2022

Apžvalgoje trumpai pristatomas pirmas Lietuvoje tokios didelės apimties biblioterapijos kompetencijų ugdymo projektas „Biblioterapijos taikymas bibliotekose“, kurio tikslas – ugdyti viešųjų bibliotekų specialistų gebėjimus sprendžiant socialinės atskirties problemas ir didinant kultūros prieinamumą visuomenei. Projekto vykdymo 2020–2021 m. laikotarpiu tinkliniu principu šalies apskričių viešosiose bibliotekose ne tik paskleistos biblioterapijos žinios, bet ir sudarytos sąlygos mokymų dalyviams dalyvauti biblioterapijos užsiėmimuose, jiems patiems sukurti ir įgyvendinti tokio pobūdžio renginį.
Impact of Electricity Supply on the Performance of Small and Medium-Scale Enterprises (SMEs) in Nigeria: A Case Study
Authors: Ajibola Akinyemi Alao , Sodeinde Gbemi Moses , Aderemi Timothy Ayomitunde , Yusuf Modupe Ololade
Published: January 2022

Despite the fact that past empirical studies have reported that numerous factors affect the performance of SMEs in Nigeria, yet power supply, which is the strategic driver of economic activities and its spillover effects on the performance of SMEs in Nigeria has not been fully investigated in the country. Against this backdrop, this study examined the impact of electricity on the performance of SMEs in Ado-Odo, Ota LGA, Ogun State. Consequently, the questionnaires were administered to the respondents using the method of purposive sampling. The data was analyzed using Statistical Package for Social Science (SPSS), variance analysis (ANOVA) and Correlations and Ordinary Least Squares (OLS) techniques. A total of 120 questionnaires were distributed, of which 90 were compiled and analyzed. The findings showed that there is significant impact of electricity supply on the performance of SMEs in Ado-Odo Ota Area, in Ogun State. Also, alternative power sources have significant impact on performance of SME in Ado-Odo Ota Area, in Ogun State. Therefore, by and large, from the findings of this study, the paper made the following recommendation for the policymakers and business owners in Ado-Odo, Ota Area of Ogun State in particular, and Nigeria by extension that sufficient supply of electricity should be placed in a place that maximizes the efficiency of small and medium-sized businesses. In the same vein, SMEs owners should strive to use alternative sources of power to boost the performance of SMEs, and meet their market objectives.
An Empirical Study of University Education and Graduate Employability in Tanzania
Authors: Mutalemwa Darlene
Published: January 2022

Few would challenge the proposition that employability skills are fundamental for success in the workplace. Yet much evidence suggests the skills mismatch and hiring talent is of great concern to employers around the globe. When it comes to ‘hard’ data with reference to employability skills in the Tanzanian context, there is a dearth of empirically verifiable statistics from an academic standpoint. The study takes up this challenge to investigate perceptions of 314 graduates on the role of university education in preparing them for the world of employment. Findings have shown a different perspective regarding the quality and employability of Tanzanian graduates. Graduates were appreciative of their university education and were confident that they can meet the requirements of the labour market. However, they acknowledged their theoretical knowledge has little value until they can apply it for practical purposes thus implying their participation in society and ability to cope with changes and recover from problems and challenges brought about by the world of work will be limited. The study urges Tanzania to cautiously devise and execute a plan for developing skills for employability within the education system and ultimately build world class-education systems which will enhance employment prospects for graduates.
Building Sustainable Food Systems - Current Dimensions and Challenges
Authors: Ene Corina
Published: January 2022

"Nowadays, there is a large consensus about the challenges our world is facing in different sectors, which are amplified by the precarious state of the global ecosystem. Various food and nutrition related issues are derived from changes in food production demand as a result of socio-economic, demographic and ecological trends which correlate with economic prosperity. In the last years, the need for a turning point in the way that food systems are functioning became obvious, as the world needs to rather be oriented towards a more sustainable future in terms of inclusiveness, health and climate-resilience.
This paper aims to emphasize the urgent nature of the need for transformation of existing food systems at all levels, underlining relevant implications and correlations, as this shifting remains the only solution to reaching relevant goals regarding both global food security and sustainability."
Agro-Allied Small and Medium Enterprises and the Economy of Kogi State, Nigeria
Authors: Dada Durotimi Amos , Alogwuja Unekwu Cynthia , Olumoyegun Mayowa
Published: January 2022

This paper focused on Agro-allied Small and Medium Enterprises and the economy of Kogi State, Nigeria. The specific aims were to ascertain the effect of agriculture on the GDP of Nigeria, and examine how entrepreneurial activities of Agro-allied SMEs affect job creation in Kogi State. The researchers employed survey research design; using purposive sampling where 120 ‘agripreneurs’ (farmers who are entrepreneurs) were selected. The study covered three senatorial districts. Both descriptive and inferential analytical techniques (Multiple Regression Model) were applied for data analysis. Finding showed that the effects of entrepreneurial activities of Agro-allied SMEs on job creation in Kogi State are weak. Furthermore, finding showed that Contribution to Agricultural Sector (CTAS) has a positive relationship with Gross Domestic Product in Nigeria. The study concluded that empowerment of Agro-allied SMEs will culminate into reduced unemployment rate. The study recommended that government should make long-term investment in the agriculture sector to increase positive impact on the GDP of Nigeria, and that the economic stakeholders should strategically empower, promote and protect the entrepreneurial activities of Agro-allied SMEs to take advantage of increased job creation in Kogi State.
Analisis Kepuasan Pelanggan PDAM Tirta Umbu Kabupaten Nias
Authors: Mendrofa Cardinal Pranatal
Published: January 2022

PDAM Tirta Umbu, Nias Regency in providing services to the management and distribution of clean water has also not satisfied customers. There were 447 complaints or customer complaints during 2018. The purpose of this study is to find out and analyze the influence of service quality and want to know and analyze the most dominant service quality elements affecting customer satisfaction PDAM Tirta Umbu, Nias Regency. This research method is descriptive with survey method approach. The population numbered 9374 customers in 2018. Data collection techniques consisted of questionnaires and documentation studies. The sample technique is accidental, with statistical analysis of multiple regression analysis. The results of research and discussion, amounting to 51.3% of customer satisfaction PDAM Tirta Umbu is influenced by the five service quality variables, while the remaining 48.7% is influenced by other variables.
The Role of Trust Toward Continuance Usage Intention: of Mobile payment with Gender as Moderation
Authors: Laurence Sontya , Candiwan
Published: January 2022

The growth of financial technology is filled by digital wallet competition in the industry, one of the most known digital payment in Indonesia is OVO. Even so, the obstacles that OVO has can make users switch to another mobile payment provider. This research aims to analyze the impact on continuance usage intention by customers’ trust, and examine factors that influence trust in terms of gender moderation, the theories developed in this study are Innovation Diffusion Theory and Trust Building Framework. The method used to process data in this study are SEM and PLS. The findings of this research state that continuance usage intention is positively influenced by trust. Trust is significantly influenced by reputation, followed by customization, security, and mobility.
Pembuatan Sistem Multiuser Untuk Persediaan Barang Dengan Metode Last In First Out
Authors: Rini Rubhiyanti  , Uswatun Khasanah  , Febryantahanuji
Published: January 2022

Business processes that are carried out still use manual recording where purchase transactions, inventory recording, and sales records are recorded in the book. Manual recording was deemed less effective and efficient and also resulted in a more complicated inventory reporting process. The purpose of this study is to develop an inventory information system using the Last In First Out (LIFO) method where the unit sold is the last unit entered, making it easier to organize goods, both entering and retrieving goods, and goods will sell quickly because they follow the trend with the latest models that generate more profit. large and this system is also equipped with a minimum stock limit report aimed at knowing the minimum stock limit of goods so that it can provide up to date notifications about out of stock items. By implementing this system, it is hoped that users will find it easier to carry out their business processes.
Analisis Hasil Ukur Sensor Load Cell untuk Penimbang Berat Beras, Paket dan Buah berbasis Arduino
Authors: Unang Achlison  , Bambang Suhartono
Published: January 2022

Measurement results of load cell sensors sometimes has a significant difference even have the same weight, this is usually caused by several factors that affect the difference in the measured value, therefore on In this research, an analysis of the measurement results of a load will be carried out with the measuring object, namely rice, package and fruit. This analysis is carried out to determine the load which object is more efficient and accurate in do some weight calculation. The process of measuring weight using a load cell sensor is carried out based on Arduino device. After the measurement results are obtained then they are analyzed and compared between the measurement results of rice, package and fruit to determine the level of efficiency of the load cell sensor. Based on the experimental results of fruit, the measurement between the results to the real value is 4%. The measurement results of fruit have the efficiency of the load cell sensor
PENGGUNAAN ASSOSIATION RULE MINING DALAM PENETAPAN HARGA PROMOSI, STOK, DAN PENATAAN PRODUK PADA ETALASE
Authors: Budi Raharjo
Published: January 2022

In the first quarter of 2017, retail in Indonesia recorded a growth of 2.5%, while in 2018 the growth was only in the range of 1% -1.5%. The cause of the slow growth is the change in the consumption pattern of the people and it will continue at the beginning of 2018. In addition, the decreasing productivity of the community at the lower middle level. As a retailer, Anterah store also faces the same thing, so anticipating a decline in sales requires an analysis of the best-selling products and how to find out the relationship between the products purchased by consumers. The association relationship between these products will be used as the basis for product arrangement, so that the frequency of products that consumers often buy can be arranged closely together so that consumers do not have to look for them longer. Market basket analysis to determine the relationship between products sold simultaneously is used to explore association rules (Association Rule Mining) which will produce products that are purchased simultaneously as a consideration for product arrangement in Anterah Retail storefront. Meanwhile, the best-selling products will be explored using the Frequent Pattern Growth method in order to obtain a ranking list of the most purchased products by consumers. This analysis is used as a basis for considering product promotion. The test results on the sales sample data obtained an average value of minimum support = 0.0025, minimum confidence = 0.610, LaPlace = 0.9985, Gain = -0.006, p-s = 0.003, Lift = 103.82, Convicting 2.5285 with a processing time of 41.456 seconds.
KEPUTUSAN BERKUNJUNG WISATAWAN DITINJAU DARI PERSPEKTIF HARGA TIKET, CITRA DESTINASI DAN FASILITAS WISATA DI HERITAGE PALACE KARTASURA
Authors: Muh. Sugeng Riyadi S  , Heni Susilowati
Published: January 2022

The purpose of this study was to determine the effect of ticket prices, destination image, tourist facilities on the decision to visit The Heritage Palace Kartasura. The research sampling technique was purposive sampling of 100 respondents. The data instrument was assessed using a Likert scale that met the validity and reliability requirements. The analysis uses multiple linear regression to test the hypothesis with the t test and F test. The results showed that partially and simultaneously the entrance ticket price, destination image and tourist facilities had a positive and significant effect on the decision to visit The Heritage Palacae Kartasura with a significant value <0.05. The ticket price variable has a dominant influence over the destination image variable and tourist facilities.
Pembiayaan Usaha Mikro Kecil Dan Menengah (UMKM) Sebagai Solusi Dalam Meningkatkan Perkembangan Usaha (Studi Kasus Pada UMKM Distrik Aimas Kabupaten Sorong)
Authors: Lahallo Fensca , Samuel Y. Warella
Published: January 2022

The purpose of this research is to compare the development of Micro, Small and Medium Enterprises (MSMEs) before and after obtaining financing (Case Study on UMKM, Aimas District, Sorong Regency). This research is a development of the results of previous author's dedication to the same subject, namely the fundamental problem of a lack of capital and access to capital sources is very difficult. This type of research is comparative research. The sample of this research is MSME actors who have received financing from both financial institutions, cooperatives, local governments, and other non-bank financial institutions for about 1 year. Data analysis to be carried out is the normality test and the Wilcoxon test. The results showed that of all the indicators studied, namely business capital, sales turnover, profit, labor, business branches, production / sales capacity and the number of customers using the Wilcoxon sign test showed that the indicators of business capital and the number of customers had significant differences before and after obtaining financing, while other indicators, namely sales turnover, profit, manpower, business branches, and production / sales capacity do not have a significant difference.
Rancang Bangun Sistem Penjualan Tunai dan Penerimaan Kas Berbasis Multiuser
Authors: Rini Rubhiyanti  , Sekar Putri Pertiwi  , Febryantahanuji
Published: January 2022

Sales are the main activity to generate profits. Sales and recording procedures that are good and according to company needs can be carried out with a sales accounting system. Cash sales and cash receipts are very important in an agency, because cash is an important asset. In recording sales and cash receipts, this agency still uses manuals. This study designed a system that is able to assist companies in calculating sales and cash receipts. With this cash sales and cash receipt information system, it is hoped that the procurement, sales planning and supervision will be carried out very well. besides that, it can also produce reports that are precise, accurate and efficient.
Sistem Informasi Manajemen Kepegawaian Penentuan Karyawan Terbaik Menggunakan Metode Analytical Hierarchy Process (AHP) Berbasis Web
Authors: Sindhu Rakasiwi  , Haryo Kusumo  , Rifal Winazar
Published: January 2022

Di era informasi dan perkembangan teknologi yang sangat pesat seperti sekarang ini, dalam rangka pengelolaan sumber daya manusia di sebuah perusahaan atau yang dikenal dengan istilah sistem informasi manajemen kepegawaian.

                Masalah yang di hadapi PT. Nerangi sarana karya yaitu Sampai saat ini, pengolaan data kepegawaian tersebut masih menggunakan sistem manual yang belum terkomputerisasi dengan baik, belum memiliki suatu database sebagai media penyimpanan data, sharing data tidak melalui jaringan dan masih mengguanakan printout hardcopy.

                Melihat permasalahan yang terjadi di subbag adminitrasi kepegawaian PT.Nerangi sarana karya, penulis bermaksut mengembangkan sebuah sistem informasi kepegawaian  ( SIMPEG) berbasis web untuk menangani  data master kepegawaian, data pegawai, data kenaikan pangkat, data kenaikan gaji berkala. menggunakan PHP dan MySQL. Metode pengembangan sistem yang penulis gunakan adalah AHP.

                Pada akhirnya, sistem ini dapat memberikan keluaran kepada penggunanya berupa SK Kenaikan pangkat, SK kenaikan Gaji berkala dan laporan pegawai.
Sistem Pengambilan Keputusan Untuk Rekomendasi Pembelian Produk Dengan Menggunakan Metode Fuzzy MCDM
Authors: Jarot Jarot Dian Susatyono , Febryantahanuji  , Iddo Elianta Herlambang
Published: January 2022

PT. Nerangi Sarana Karya sering mengalami beberapa masalah karena jumlah pengadaan yang dibeli banyak namun belum ada sistem yang membantu untuk merekomendasikan pembelian produk, contohnya pada tanggal 9 bulan oktober 2018 PT. Untuk mengatasi masalah yang terjadi di PT Nerangi Sarana Karya perlu diterapkan sistem pengambilan keputusan menggunakan metode Fuzzy MCDM, berdasarkan hasil pengujian data bahwa metode ini memiliki tingkat akurasi analisa data sebesar 87% sehingga metode ini cukup layak untuk digunakan dalam pengambilan keputusan.
Kompetensi dan Motivasi Sebagai Variabel yang Mempengaruhi Kinerja Karyawan RSUD. Sultan Fatah Demak
Authors: Syamsul Hadi  , Andhi Supriyadi
Published: January 2022

This research was conducted to be able to find out the influence of competency and motivation variables on the performance of RSUD Sultan Fatah Demak employees. And it can also be known which variables have the highest influence on the performance of RSUD Sultan Fatah Demak employees. The method used in this study is a quantitative method, using statistical methods using questionnaires given to respondents. Respondents will answer by choosing numbers from existing statements about the influence of Competence and Motivation on the Performance of RSUD Sultan Fatah Demak employees. This research uses the study of library methods, questionnaire methods which are then processed with SPSS  for windows 25.0. The sample of respondents in the study was 78 people. From the results of research both variables can be known motivation is shown as a variable that has the highest influence on employee performance in RSUD. Sultan Fatah with more value of 0.511 to employee performance
P Pengaruh Partisipasi Anggaran, Kejelasan Anggaran, Komitmen Organisasi Terhadap Senjangan Anggaran
Authors: Siswiraningtyas Anggraeni Nur , Indrawati Yuhertiana
Published: January 2022

Riset ini bertujuan untuk menguji dan menganalisis pengaruh partisipasi penyusunan anggaran, kejelasan sasaran anggaran, komitmen organisasi terhadap senjangan anggaran. Riset ini menggunakan jenis kuantitatif dengan menggunakan data primer. Data primer tersebut yaitu kuesioner yang disebar kepada responden. Teknik analisis data yang digunakan dalam riset ini adalah adalah PLS-SEM dengan bantuan perangkat lunak SmartPLS versi 3.0 for windows. Hasil riset membuktikan bahwa variabel partisipasi penyusunan anggaran, kejelasan sasaran, serta komitmen organisasi memiliki pengaruh terhadap senjangan anggaran.
Studi Financial Statement Fraud dengan Fraud Triangle Theory
Authors: Chandrawati Novalia Budi , Dyah Ratnawati
Published: January 2022

Tujuan penelitian ini adalah untuk menguji pengaruh financial stability, external pressure, nature of industry, dan rationalization terhadap financial statement fraud. Sampel yang digunakan dalam penelitian ini adalah perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia pada periode 2018-2019. Dengan menggunakan metode purposive sampling diperoleh sebanyak 77 perusahaan manufaktur sebagai sampel penelitian. Metode analisis yang digunakan dalam penelitian ini adalah regresi logistic. Dalam penelitian ini terdapat uji model fit keseluruhan, tes hosmer dan lemeshow, uji goodness of fit, dan matrik klaifikasi. Hasil penelitian meneunjukkan bahwa financial stability berpengaruh signifikan terhadap financial statement fraud, sedangkan external pressure, nature of industry, dan rationalization tidak signifikan terhadap financial statement fraud
Hourly historical and near-future weather and climate variables for energy system modelling
Authors: Bloomfield Hannah C. , Brayshaw David J. , Deakin Matthew , Greenwood David
Published: January 2022

Abstract. Energy systems are becoming increasingly exposed to the impacts of weather and climate due to the uptake of renewable generation and the electrification of the heat and transport sectors. The need for high-quality meteorological data to manage present and near-future risks is urgent. This paper provides a comprehensive set of multi-decadal, time series of hourly meteorological variables and weather-dependent power systems components for use in the energy systems modelling community. Despite the growing interest in the impacts of climate variability and climate change on energy systems over the last decade, it remains rare for multi-decadal simulations of meteorological data to be used within detailed simulations. This is partly due to computational constraints, but also due to technical barriers limiting the use of meteorological data by non-specialists. This paper presents a new European level dataset which can be used to investigate the impacts of climate variability and climate change on multiple aspects of near-future energy systems. The datasets correspond to a suite of well-documented, easy-to-use, self-consistent hourly- nationally-aggregated and sub-national time series for 2 m temperature, 10 m wind speed, 100 m wind speed, surface solar irradiance, wind power capacity factor, solar power factor and degree days spanning over 30 European countries. This dataset is available for the historical period (1950–2020), and is accessible from https://researchdata.reading.ac.uk/id/eprint/321 with reserved DOI: http://dx.doi.org/10.17864/1947.000321 (Bloomfield and Brayshaw, 2021b). As well as this a companion dataset is created where the ERA5 reanalysis is adjusted to represent the impacts of near-term climate change (centred on the year 2035) based on five high resolution climate model simulations. This data is available for a 70 year period for central and Northern Europe. The data is accessible from https://researchdata.reading.ac.uk/id/eprint/331 with reserved DOI: http://dx.doi.org/10.17864/1947.000331 (Bloomfield and Brayshaw, 2021a). To the authors’ knowledge, this is the first time a comprehensive set of high quality hourly time series relating to future climate projections has been published, which is specifically designed to support the energy sector. The purpose of this paper is to detail the methods required for processing the climate model data and illustrate the importance of accounting for climate variability and climate change within energy system modelling from sub-national to European scale. While this study is therefore not intended to be an exhaustive analysis of climate impacts, it is hoped that publishing this data will promote greater use of climate data within energy system modelling.