bluuebunny/crossref_metadata_2025 huggingface dataset:
Fluoropirimidinas y variantes del gen DPYD
Authors: Marcolini Nicolás , Carballido Marcela , Gayet Preiss Fernando , Picon Carlos Rafael , Valderrama Wbeimar , Quenardelle Mariano , Esteso Marcos , Rizzo Manglio , Bayo Juan
Published: December 2024

Las fluoropirimidinas son quimioterápicos antimetabolitos usados en varios tipos de cáncer. El 5-fluorouracilo (5-FU) actúa inhibiendo la síntesis de ADN y ARN mediante sus metabolitos activos, que interfieren con la timidilato sintasa y se incorporan en los ácidos nucleicos, bloqueando así la proliferación celular. La eliminación de estas drogas depende de la enzima dihidropirimidina deshidrogenasa (DPD), codificada por el gen DPYD. Mutaciones en DPYD, presentes en un 3-7% de la población según lo reportado, pueden reducir la actividad de la DPD, lo que aumenta el riesgo de toxicidad grave al acumularse el 5-FU. La función de la DPD puede evaluarse mediante estudios genotípicos de DPYD o fenotípicos, como la medición de uracilemia. Esto permite ajustar las dosis para minimizar efectos adversos en pacientes con actividad reducida de la DPD, mejorando la seguridad del tratamiento.
Situación de los oncólogos en formación en Argentina
Authors: Basbus Luis , Elaskar María Cielo A. , Narvaez Dana , Illia Maria , Bulacio Jose Santos , Ortega Chahla Elías , Godoy Victoria , Sarru Florencia
Published: December 2024

Introducción: La formación de oncólogos en Argentina enfrenta diversos desafíos, lo que afecta tanto el desarrollo profesional de los médicos como la calidad de la atención oncológica en el país.
Este estudio explora las percepciones, expectativas y experiencias de los oncólogos jóvenes en formación en Argentina, con el objetivo de identificar las barreras que limitan su desarrollo y proponer soluciones.
Métodos: Se utilizó un enfoque mixto (cualitativo y cuantitativo) mediante encuestas semi-estructuradas a 57 médicos residentes y especialistas en oncología con menos de cinco años de experiencia.
Resultados: La mayoría de los encuestados (68%) tiene menos de cinco años de experiencia y se encuentran principalmente en Buenos Aires y CABA (63%) y la región central del país (29%). Si bien el 84% de los participantes tiene acceso a formación en oncología en sus provincias, un 39% considera que su formación es parcialmente adecuada, y más de la mitad se siente insatisfecho con su unidad formativa. Los principales desafíos incluyen bajos salarios (80%), falta de recursos (67%) y una alta carga de trabajo (63%). Además, un 70% de los participantes considera necesario mejorar la formación en investigación y publicaciones científicas, el 70% refiere que el estrés laboral ha afectado su salud física o mental en el último año. 
Conclusión: Es crucial desarrollar políticas públicas que promuevan la equidad en el acceso a la formación médica, mejoren las condiciones laborales y fomenten la investigación, garantizando una mejor preparación para los oncólogos del futuro.
Utilizing YouTube Videos as Instructional Media to Advance EFL Learners’ Speaking Fluency (Evidence from Indonesian Native Speakers as EFL Learners)
Authors: Pakpahan Marnangkok
Published: December 2024

This study investigated the impact of using YouTube videos as instructional media on advancing speaking fluency in an English conversation class. A quasi-experimental design with pre- and post-tests was employed, involving 30 first-semester students from an English Language and Culture program in Pontianak, Indonesia, using total population sampling. Data collection included two oral speaking tests, a speaking fluency rating scale, and a questionnaire. A mixed-methods approach (quantitative and qualitative) was used for data analysis. Results showed that the mean post-test score (78) was significantly higher than the pre-test score (67.65), with a difference of 10.35 points. This indicates that YouTube videos are highly effective in improving EFL learners’ speaking fluency. The study highlights the importance of incorporating effective instructional media in EFL education to better address students' learning needs and enhance engagement, ultimately leading to more effective language learning outcomes.
Krisis Lingkungan Berskala Internasional dalam Perspektif Fiqh Ekologi
Authors: Habibi Muhammad , Nabilah Febriana
Published: December 2024

Humans, as stewards of the earth, are entrusted with the responsibility of preserving environmental balance through the use of reason and conscience, which collectively form international ecological wisdom. Environmental preservation becomes effortless and natural when rooted in everyday human practices, ensuring the sustainability of nature without the need for punitive measures or external enforcement. This paradigm is explicitly reflected in the nation's constitution, particularly in Article 33, paragraphs (3) and (4) of the 1945 Constitution, which encapsulates the principle of a "green constitution." In Islam, the divine law aims to maintain human harmony and prevent destruction. The primary sources of Islamic law—the Qur’an, hadith, and the evolving discipline of Fiqh Ecology—offer solutions to the global environmental crisis. This study employs a normative approach with a doctrinal focus and is descriptive-analytical in nature. Therefore, the research seeks to address the international environmental crisis from the perspective of Fiqh Ecology, presenting it as a framework to confront current ecological challenges.
Environmental Sociology
Authors: Kropp Cordula , Sonnberger Marco
Published: December 2024

Mankind is facing great challenges because there are justified concerns that its relationship with nature is not sustainable. However, societies, milieus and fields of action differ considerably in their interactions with the so-called environment. What the ecological crisis means from a sociological perspective and what role environmental attitudes, consumption patterns, innovations, infrastructures or risks play in it is explained in this introduction to environmental sociology with references to many examples. This textbook introduces students of sociology and social sciences to the central questions, theories and subjects of environmental sociology in 10 incisive chapters, which can also be read individually.
Algorithmic Decision-Making in Service Work
Authors: Glock Gina
Published: December 2024

Far-reaching transformations in the world of work are being discussed vividly under the term ‘artificial intelligence’. Questions are arising about the changing role of humans in work processes and their freedom to determine work content and conditions. This book explores these potential areas of conflict and examines how algorithmic decision-making systems influence the job autonomy of service workers. Using case studies from outpatient care and banking services, this book shows under which organisational conditions positive experiences of autonomy are enabled. Dr Gina Glock is a work sociologist, who researches the interplay of work and digitalisation.
Verletzteninteressen im Kontext des staatlichen Umgangs mit Straftaten
Authors: Riebel Marius
Published: December 2024

physical and psychological impairments. This gives rise to various needs and expectations that are directed at state institutions. This study, which focuses on criminal procedural law, sheds light on existing possibilities as well as the potential for considering the interests of injured parties in state proceedings aimed at dealing with criminal offenses. In addition to an analysis of criminal procedural law and social compensation law, the work deals with alternative victim-centered procedures.
Effectiveness of a Collaborative, Virtual Outreach Curriculum for 4th-Year EM-bound Students at a Medical School Affiliated with a Historically Black College and University
Authors: Brown Cortlyn , Carter Richard , Hartman Nicholas , Hammond Aaryn , MacNeill Emily , Holden Lynne , Pierce Ava , Campbell Linelle , Norman Marquita
Published: December 2024

Background: Diversity within the physician workforce is associated with improved clinical outcomes and patient satisfaction. Despite this, the US physician workforce, particularly in emergency medicine (EM), remains relatively homogeneous. Of all Black medical school students in the US, 14% attend the four Historically Black Colleges and Universities (HBCU) that have a medical school. Unfortunately, none of these schools are afﬁliated with an academic EM program. Because of this, there is less professional mentorship focused on obtaining a career in EM and potentially less formal curricula for senior medical students doing their home sub-internship in EM. Objectives: Our objective was to ﬁll the gap left by the absence of an academic EM department at Howard University College of Medicine (HUCOM) by creating a collaborative educational experience for fourth-year medical students during their home EM sub-internship. The curricular objectives were to teach core principles of EM, build relationships with students, and prepare them for pursuing EM residency training. Curricular Design: Four EM academic departments collaborated to create and implement a virtual curriculum using the six-step approach to curricular development. Impact/Effectiveness: After completion of the course, ﬁve students (100%) reported strongly agreeing with the following statements. These sessions 1) helped me learn the approach to core EM topics more than I would have been able to do on my own; 2) helped me learn key skills for excelling in an EM rotation more than I would have been able to do on my own; and 3) allowed me to connect with faculty and resident mentors to learn more about the ﬁeld of EM. Of these ﬁve students, 80% and 20% reported strongly agreeing and agreeing, respectively, that these sessions helped them learn about the process of applying to and selecting an EM residency program.
Opioid-Free Anesthesia for Upper Limb Surgery in Obese Patients as a Day Case Surgery: A Prospective Observational Study
Authors: Ahmed Abdelghaffar Rana , Ahmed Hamed Mohamed , Magdy Basiony Mohammed , Fouad Algyar Mohammad , Sayed Fargaly Omar , Ahmed Shawky Mohamed
Published: December 2024

Background: Opioid-free anesthesia (OFA) is a relatively new approach, and many studies are still needed to assess its effectiveness and compare it to opioid-based anesthesia (OBA). Objectives: This study investigated the use of OFA in obese patients undergoing upper limb surgery and compares its outcomes with those of OBA. Methods: This prospective randomized clinical study included 76 obese patients with a Body Mass Index (BMI) ≥ 30 kg/m² who were scheduled for upper limb surgery. Patients were randomly assigned to receive either OFA (group A, n = 38) or OBA (group B, n = 38). The OBA group was administered propofol, fentanyl, and atracurium, while the OFA group received lidocaine, propofol, atracurium, and dexmedetomidine. All patients were mechanically ventilated, and anesthesia was maintained with isoflurane and atracurium. Primary outcomes monitored included postoperative pain [Visual Analog Scale (VAS) ≥ 4] and the number of rescue doses of tramadol. Secondary outcomes included extubation time, any cardiac events, hypoxia, postoperative nausea and vomiting (PONV), intensive care unit (ICU) admission rates, and duration of hospital stay. Results: The OFA group had significantly lower extubation time, mean arterial pressure (MAP), and heart rate (HR) compared to the OBA group. Additionally, VAS scores were significantly lower at the 30-minute and 2-hour marks after extubation (P < 0.001 and P < 0.001, respectively) in patients receiving OFA. The OFA group also experienced fewer adverse effects, required fewer rescue doses of tramadol, and had shorter hospital stays. Conclusions: Opioid-free anesthesia may result in better and safer outcomes for obese patients undergoing upper limb surgeries, with fewer postoperative complications and shorter hospital stays. However, further research is needed to fully understand the potential benefits of OFA compared to OBA.
Exploring the Efficacy of Occupational Therapy (OT) in Addressing Post-COVID Symptoms: A Scoping Review
Authors: Ghanbari Sahar , Zamiran Sara , Rezaei Amin
Published: December 2024

Context: Some researchers proved new and persistent symptoms lasting for weeks and even months after COVID that is named “long-COVID” or “post-COVID syndrome.” It appears that occupational therapists (OTs) have a significant role in managing the symptoms of long COVID, with the aim of enhancing patients' ability to perform daily activities and improving their overall well-being. The objective of this study was to conduct a scoping review study of reputable databases to identify the various ways in which OTs can manage long COVID from the onset of symptoms. Evidence Acquisition: To identify relevant documents, the following databases and search engine were searched from 2019 to 2023 in the English language: PubMed, Scopus, ISI, and Google Scholar. Keywords used for search include (("occupational therapy") AND (("post-COVID") OR ("long-COVID"))) AND ((intervention) OR (exercise)), of which 45 articles were found, and a total of 22 were chosen according to the predetermined criteria. Results: A diverse array of interventions in OT can be useful for the management of post-COVID symptoms, as mentioned in the 22 studies found as the search result, including energy management education, pulmonary rehabilitation, sleep hygiene, stress and fatigue management, and work simplification. Conclusions: Occupational Therapist offers a distinctive viewpoint on health conditions that arise in human life, and its interventions can be utilized to enhance health, self-management, and quality of life (QOL).
The Effect of Intrauterine Administration of Growth Hormone on IVF Success Rate in Recurrent Implantation Failure Women: A Randomized Clinical Trial
Authors: Amirkhanloo Fatemeh , Javanbakht Mohammad , Lotfi Sarah , Sahraiyan Ghazal , Akbari Razieh , Feizabad Elham , Rahimi Shima , Ebrahimi Mahbod , Akbari Asbagh Firouzeh , Davari Tanha Fateme
Published: December 2024

Background: The positive effects of growth hormone (GH) on the endometrium, including increased endometrial blood supply and enhanced expression of cytokines associated with endometrial receptivity, have been noted. However, data on the effect of GH on the endometrium remain limited. Objectives: This study aimed to investigate the effect of intrauterine administration of GH on the IVF success rate in women with recurrent implantation failure (RIF). Methods: This randomized double-blind clinical trial was conducted on 60 infertile women under 40 years old with a Body Mass Index (BMI) below 30 kg/m², all diagnosed with RIF—defined as at least three failed pregnancies after transferring a minimum of four good-quality embryos due to unknown causes. Women with uterine malformations, Asherman syndrome, cavity-distorting lesions, severe endometriosis, or other underlying diseases were excluded. After six days of estrogen therapy, transvaginal ultrasound (TVS) was performed to measure and compare the thickness and quality of the endometrium. Participants were divided into two groups. In the intervention group, 10 units of GH were administered using an IUI catheter positioned one centimeter above the cervical os. Study outcomes included changes in endometrial thickness (ET) and quality, as well as pregnancy rates. Primary endpoints were changes in ET and quality, while secondary endpoints were pregnancy rates. Adverse drug responses were also evaluated. Results: The mean age was 34.96 ± 4.04 years, and the mean BMI was 24.89 ± 2.91 kg/m², with no significant differences in baseline variables between the study groups. The average ET on the 8th day of the cycle was 5.38 ± 0.96 mm in the intervention group and 5.20 ± 0.80 mm in the control group, showing no significant difference (P = 0.467). The ET on the day of initiating progesterone was 7.60 ± 1.03 mm in the intervention group and 7.40 ± 0.60 mm in the control group, with no significant difference (P = 0.264). The odds ratio for achieving a high-quality endometrium was 2.37 (95% CI 0.80 - 6.98, P = 0.116) for the GH group compared to the non-GH group. The odds ratio for achieving a clinical pregnancy was 3.06 (95% CI 0.54 - 17.37, P = 0.205) for the GH group compared to the non-GH group. Two cases of cervicitis were reported in the GH group. Conclusions: Intrauterine administration of GH appears to enhance endometrial receptivity in women with RIF.
High Cognitive Functioning ADHD: A Veterinary Student's Perspective and Literature Review
Authors: Medghalchi Nazanin , Hassanzadeh Rad Afagh , Zavar Mousavi Maryam
Published: December 2024

: This study provides a comprehensive review of attention deficit hyperactivity disorder (ADHD), discussing its historical background, prevalence, symptoms, subtypes, comorbidities, and treatment options. ADHD, characterized by inattention, hyperactivity, and impulsivity, affects an estimated 5 - 10% of children and 4% of adults worldwide, with a higher diagnosis rate in boys. However, underdiagnosis in girls due to less overt symptoms is a growing concern. The study begins with the case of a girl diagnosed with ADHD, using her experiences to highlight the specific challenges faced by individuals with high cognitive functioning ADHD. This case serves as an entry point to examine how ADHD impacts those who, despite intellectual or academic strengths, struggle with focus, organization, and impulse control. These insights are further explored through the perspective of a veterinary student managing ADHD, offering a unique view on how the disorder interacts with high academic and professional demands. The review examines the various subtypes of ADHD—predominantly inattentive, predominantly hyperactive-impulsive, and combined—and discusses common comorbidities such as anxiety, depression, learning disabilities, and sleep disorders. Current treatment approaches, including behavioral interventions, pharmacotherapy, and cognitive-behavioral therapy, are evaluated for their effectiveness in managing ADHD symptoms. A key theme of this study is the importance of societal awareness in reducing stigma, which can facilitate early diagnosis and access to appropriate treatment. The findings emphasize the need for individualized, holistic approaches to care that address the unique needs and strengths of each person with ADHD. Early intervention and a personalized treatment plan can significantly improve outcomes, leading to better academic performance, emotional regulation, and overall quality of life for individuals with ADHD.
Establishment of the District Youth Care in Dolný Kubín...: the Development of Social Care for Children and Youth in the Years 1930–1945
Authors: Vešelényiová Frederika
Published: December 2024

The 1930s and 1940s marked a period of significant transformation in social care within the First Czechoslovak Republic. In an effort to unify fragmented legislation and establish an effective social welfare system, particular attention was directed towards the needs of minor children and adolescents, who represented one of the most vulnerable segments of the population. This study examines the establishment and operation of the DistrictYouth Care in Dolný Kubín, focusing on its role in providing social care for minors in one of the poorest regions of Slovakia.
Subjectivism, Objectivism and Contractual Opportunism: A Pragmatic Explanation of an Age-Old Question
Authors: Botu Cristian-Codrin
Published: December 2024

This paper examines the relationship between the objective and subjective theories of contract interpretation from both historical and teleological perspectives. It introduces the concept of contractual opportunism in this matter and reviews existing legal literature on the topic to elucidate the distinctions and connections between the interpretive theory based on the internal will of the parties and the one which looks at their objectively manifested intentions. By analysing the foundational ideas of W. Paley and R. J. Pothier, it highlights the importance of integrating pragmatic elements into the discussion. The paper concludes that a purely dogmatic analysis is insufficient in this area, and instead we must consider the underlying purpose of the theories: to discourage and prevent contractual opportunism.
The Rules of Cumulative Sentencing in the Csemegi Code of Hungary
Authors: Zsanett Dorang
Published: December 2024

This study examines the regulation of cumulative sentencing in 19th-century Hungary under Act V of 1878, known as the Csemegi Code. During this period, the term “subsequent fixing of aggregate sentences” was used, which led to interpretative confusion. The regulation had its roots in German law but was adapted with significant modifications that influenced the historical development of this legal institution and continue to impact contemporary interpretations. The presentation will address the historical regulation, the codification process, the clarity of the norms, and the interpretive challenges faced by both legal practitioners and scholars, particularly in relation to joinder and cumulative sentencing. The study aims to demonstrate how a single change in terminology had a profound effect on the evolution of the legal framework. Additionally, it will discuss how Károly Csemegi vividly described the complexity of joinder, comparing the legal uncertainties surrounding it to the disruption caused by an earthquake.
The Movement for Changing the Property Laws of Married Women in England, 1856–1870
Authors: Bažantová Eva
Published: December 2024

In the middle of the 19th century, all property and earnings of a married woman belonged to her husband, including the property that a woman owned before entering the marriage. In 1856, Barbara Bodichon submitted the first petition to the Parliament of Great Britain that called for changing the property laws (Married Women’s Property Acts) and the long-lasting efforts to gain property rights and economic and legal independence for married women had begun. The paper will focus on the movement for changing the Property Laws of Married Women in England between the years 1856 and 1870, i.e. from the submission of the first petition by Barbara Bodichon to the first milestone – issuing the law that gave married women in England some property rights, Married Women’s Property Act 1870.
Villgro: Crafting an Incubator
Authors: ISDM CSIP
Published: December 2024

This case study engages with the journey of Villgro, a social enterprise “incubator” founded in 2001 by Paul
Basil. Initially coming into being with a focus on rural, grassroots innovators and entrepreneurs, Villgro
looked to scout for, support and grow their ideas into viable enterprises, with the ultimate goal of rural
prosperity and wealth creation. It has today grown into an important part of the social enterprise landscape
in India. This case traces Villgro’s journey in laying the foundations for and contributing to the development
of an ecosystem able to support and nurture early-stage innovations; and explores in detail what an
end-to-end incubation process entails.
Le match de football, un rituel religieux ?
Authors: Bromberger Christian
Published: December 2024

Le match de football a toutes les apparences d’un rituel religieux, y compris à travers les valeurs qu’il communique, mais ne nous dit rien des causes premières et des fins dernières, à savoir d’où nous venons et où nous allons. Il s’agit d’un rituel « sans exégèse », une forme de rituel qui abonde dans les sociétés contemporaines.
Charles Émile Drago, l’orfèvre dans les arcanes du football français d’après-guerre
Authors: Vincent Guillaume
Published: December 2024

Charles Émile Drago, bijoutier niçois spécialisé dans les décorations militaires et civiles, propose, en 1953, au Groupement des clubs autorisés, l’ancêtre de la Ligue de football professionnel, de doter son challenge nouvellement créé d’un remarquable trophée. La compétition, sorte de consolante de la Coupe de France qui deviendra plus communément la « Coupe Drago », met en lumière l’activité d’un mécène influent dans le cénacle des dirigeants du football professionnel entre les années 1950 et 1970, dont l’engagement le poussera même à créer l’Association internationale pour un sport sans violence.
Le vignoble argentin au miroir de l’histoire mondiale du vin du début du xxe siècle à nos jours. Interactions et évolutions
Authors: Jacquet Olivier , Wolikow Serge
Published: December 2024

Ici, la démarche proposée ne consiste pas, en réalité, à étudier le vignoble argentin sous le prisme de son histoire territoriale locale, mais à l’analyser sous une focale globale capable de mettre en exergue l’intérêt des dimensions internationales et historiques dans les études sur les pays vitivinicoles. Ainsi, et même si un vignoble est bien localisé, sa connaissance impose aussi qu’elle soit connectée avec la situation internationale. Si aujourd’hui cette remarque apparaît banale, elle vaut également pour les périodes antérieures : tout au long des xixe et xxe siècles, la situation des vignobles, qu’ils soient européens ou non, a ainsi été largement dépendante des conjonctures et réglementations internationales. À ce titre, l’Argentine fut, dès le début du xxe siècle, un acteur incontournable de la viticulture et des vins au plan mondial. Le pays sera d’ailleurs, dès le début 1929, l’un des premiers États à adhérer à l’Office International de la Vigne et du Vin (OIV) créé 5 ans plus tôt.À partir de la très riche documentation du Bulletin de l’OIV, numérisé et indexé à l’Université de Bourgogne, nous proposons de présenter une communication qui mette en lumière la manière dont le vignoble argentin a été perçu à l’échelle mondiale ainsi que la représentation que ses différents acteurs ont voulu donner de leur pays, au cours de l’histoire, dans la sphère vitivinicole internationale. À travers cet exemple, notre réflexion portera sur les interactions et les interconnexions entre histoire nationale et globale dans le domaine de la vigne et du vin.
Catálogo del paisaje del viñedo, Mendoza, Argentina. Un instrumento para su planificación y gestión
Authors: Girini Liliana , Médico Carina , Vicchi María Jimena
Published: December 2024

El trabajo muestra la aplicación del instrumento “Catálogo del paisaje del viñedo” en el distrito de Lunlunta, Maipú, Mendoza, Argentina, donde se concentran los viñedos más antiguos de la región. Este paisaje, heredado de la época de la modernización de la vitivinicultura de fines del siglo XIX y su evolución hasta nuestros días, presenta atributos singulares. Paradójicamente estos viñedos ubicados en la zona de interfase urbano-rural se ven amenazados por el avance de la urbanización con la proliferación de barrios privados, asentamientos inestables y barrios de vivienda social. Consideramos que su preservación es prioritaria no solo por el valor económico-productivo sino por sus valores ambientales, identitarios y culturales. A este fin se diseñó el “Catálogo” para identificar, describir y cualificar el paisaje del viñedo de Mendoza con el objetivo de que se convierta en una herramienta para la gestión del paisaje y el ordenamiento del territorio. El artículo se estructura en dos partes; la primera, presenta sintéticamente el “Catálogo” y la segunda, muestra su aplicación al caso de estudio. Como resultado, se muestran los componentes del paisaje, sus relaciones e interdependencias, revelando su “carácter”, valores, potencialidades y conflictos subyacentes.
Kesadaran Dan Kepatuhan Halal Melalui Lembaga Pendamping Sertifikat Halal Pada Industri Makanan Berbahan Sembelihan
Authors: Shafa Putri , Syahkhoni Mohammad , Raihan Muhamad Taufiq , Harmono Harmono , Handiriono Raden
Published: December 2024

Penelitian ini membahas kesadaran dan kepatuhan terhadap sertifikasi halal dalam industri makanan berbahan sembelihan, dengan fokus pada peran Lembaga Pendamping Sertifikat Halal (LPSH). Isu spesifik yang diangkat adalah rendahnya tingkat kesadaran dan kepatuhan pelaku usaha terhadap kewajiban sertifikasi halal yang ditetapkan pemerintah Indonesia. Hal ini memengaruhi daya saing produk di pasar global dan kepercayaan konsumen Muslim. Penelitian ini bertujuan untuk mengeksplorasi peran LPSH dalam meningkatkan kesadaran dan kepatuhan pelaku usaha terhadap standar halal, mengidentifikasi hambatan yang dihadapi, dan menawarkan solusi yang dapat diterapkan dalam industri makanan berbahan sembelihan.
Metode penelitian yang digunakan adalah yuridis empiris dengan pendekatan studi kasus, melibatkan wawancara mendalam, observasi langsung, dan analisis dokumen terkait peraturan perundang-undangan dan laporan lembaga terkait. Hasil penelitian menunjukkan bahwa LPSH berperan penting dalam memberikan pendampingan teknis, pelatihan, dan pengawasan yang efektif, sehingga meningkatkan tingkat kepatuhan pelaku usaha. Namun, hambatan seperti kurangnya pemahaman regulasi, biaya sertifikasi yang tinggi, dan prosedur administrasi yang kompleks tetap menjadi tantangan signifikan. Implikasi penelitian ini mencakup rekomendasi untuk memperkuat kolaborasi antara pemerintah, lembaga sertifikasi, dan pelaku usaha. Selain itu, diperlukan kebijakan yang mendukung insentif finansial dan penyederhanaan prosedur sertifikasi untuk meningkatkan daya saing produk halal Indonesia di pasar global.
Urban Nomads
Authors: Droma Nyema
Published: December 2024

Artist statement by Nyema Droma for her Untitled photograph taken in Sungchu, Ngaba, 2018.
Letter from the Editors
Authors: R. Schaeffer Kurtis , Quintman Andrew
Published: December 2024

Letter from the Editors.
Interview with Bhuchung D. Sonam
Authors: D. Sonam Bhuchung
Published: December 2024

An interview with the Tibetan poet, writer, translator and publisher Bhuchung D. Sonam based in Dharamshala, India.
བོད་པ་སྙན་ངག་པ་དང་རྩོམ་པ་པོ། ལོ་ཙྰ་བ། དཔེ་དེབ་པར་འགྲེམས་བྱེད་མཁན་བུ་ཆུང་བསོད་ནམས་ལ་བཅར་འདྲི་བྱས་པ་ཞིག །
Kajian Isu Pendidikan Islam Kontemporer
Authors: Sukari Sukari , Setiawan Rizka
Published: December 2024

The Islamic religion has a position as rahmatan lil 'alamin, which is a pillar of moral civilization for the sake of sustainability in today's contemporary era. Handling various contemporary issues requires a comprehensive view/mindset that can provide an example and positive attitude to the new generation, especially postgraduate students of the Islamic Religious Education Study Program as carriers of a new generation of Islam who are superior in morals and manners. The aim of the research is to understand contemporary issues in Islamic education by describing problems, perspectives and problem systems accompanied by solutions. The research targets are students of the Islamic Religious Education (PAI) study program in particular and Muslims in general. The data collection technique is carried out through factual documents in the form of scientific journals, textbooks and trusted news websites. The data analysis technique uses qualitative descriptive analysis by describing information about contemporary Islamic education issues that arise and develop in everyday society. The location of this research is the Mamba'ul Ulum Islamic Institute Campus, Surakarta City with the subjects being postgraduate students of the Islamic Religious Education Study Program for the 2024/2025 academic year. Data collection uses in-depth interviews. The results of the research show that students know contemporary terms and how to deal with the world of contemporary education so that they are the right group to face the issues of Islamic education in that era. Contemporary Islamic education has crucial issues because it concerns the existence of morals and deep paradigms regarding the quality of deepening and practicing education according to the Al-Qur'an and Hadith in the current era of advanced technology. The presence of Islamic religious education and the issues that occur can give us wisdom that every era will have its challenges and be accompanied by concrete everyday solutions in accordance with Islamic principles.
Pengembangan Media Pembelajaran Interaktif untuk Meningkatkan Budaya Toleransi di SDN Pondok Bambu 15 Pagi
Authors: Pratama Nauval Satria , Laily Annida Nur Alfi , Madya Dika Putra , A'yun Virza Qurrota
Published: December 2024

Building a culture of tolerance among children is made more difficult by the growing ethnic and cultural diversity at State Elementary School 15 Pondok Bambu Pagi, which is the subject of this study. Different student backgrounds can lead to divergent opinions and possible confrontations; therefore, it's important to really try to teach them the value of tolerance. Researching and developing interactive learning materials in the form of digital comics with the goal of promoting the comprehension and implementation of intercultural tolerance ideals in the classroom is the goal of this research. Research and development (R&D) is the methodology employed in this study, and questionnaires and interviews were utilized to gather data. Two Islamic religious education educators were interviewed in order to determine the requirements and expectations in the advancement of the media. Data on the quality assessment of the produced media, which was based on assessments by media and material specialists, was also gathered through questionnaires. It is intended that this digital comic medium would help the students of SDN Pondok Bambu 15 Pagi develop a more tolerant culture.
تطبيق طريقة الغناء حفظ الأمثلة التصرفية لتنمية مهارة كتابة الطلاب المدرسة المتوسطة ميدان التعليم مايانجان جومبانج
Authors: Ilmi Khafidhotul
Published: December 2024

Arabic linguistics makes a great effort to ensure that students understand the material and acquire the Arabic language that has been studied seriously. Students who lack motivation expect the teacher to provide an exciting and innovative educational approach, both in terms of content and process, including teaching methods and means of teaching Arabic.This research aims to (1) How to apply the singing method to develop students' writing ability in middle school education field? (2) What are the obstacles and motivations of the singing method in memorizing behavioral examples to develop students' writing skill in middle school education field? The method used here is the qualitative method, which means that the data collection method is done through direct observation, interviews, and documentation.The results of this research are: (1) It can be seen that the use of songs to improve students' writing skills can be seen through students' interest in learning in class, which helps students understand the material easily. The songs used in teaching are diverse. Sometimes students adopt popular songs at the moment. (2) Internal factors and external factors. Among these factors is interest in learning, which is shown through students' enthusiasm, diligence, and pleasure in following the lessons.
Changing places and writing the postcolonial novel
Authors: Gurnah Abdulrazak , Hadfield Andrew
Published: December 2024

In this conversation Abdulrazak Gurnah, winner of the Nobel Prize for Literature (2021), discusses the nature of his fiction and how he became a writer. He outlines the factors that made him become a writer; the themes that he explores in his writing; the nature of his writing style; his literary allusions; the importance of family and the secrets that families keep; and his conception of his reader. The conversation highlights the significance of exile in his work, the ways in which people belong in communities, how frightening isolation can be for individuals, and how people cope in adverse circumstances.
Dil İşleme Botlarının E-Ticaret Sektöründe Rekabet Üzerindeki Etkileri: Bir İnceleme
Authors: İbrahimoğlu Enver , Mohamed Ali Nada
Published: December 2024

Bu çalışma, dil işleme (Dİ) botlarının e-ticaret sektöründeki rekabet üzerindeki etkilerini incelemektedir. Dİ teknolojisi, e-ticaret platformlarında müşteri hizmetleri, ürün önerileri, pazarlama ve satış süreçlerinde önemli bir rol oynamaktadır. Çalışmada, Dİ botlarının e-ticaret işletmelere verimlilik ve rekabet açısından nasıl avantaj veya dezavantaj sağladığını araştırılmıştır. Bu amaçla Dİ'nin e-ticaretteki kullanım alanları, yararları belirlenmiş ve “Amazon.com” örneği üzerinde e-ticaret şirketleri üzerinden satış verilerine, rekabet koşullarına nasıl katkı sağladığı ifade edilmiştir. Müşteri hizmetleri botları, kullanıcıların sorularını hızlı ve etkili bir şekilde yanıtlayarak müşteri memnuniyetini artırabilirken, ürün öneri botları ise müşterilere kişiselleştirilmiş alışveriş deneyimleri sunarak satışları artırabilir. Buna ek olarak, pazarlama ve satış botları da müşteriye özel kampanyalar ve indirimler sunarak rekabet açısından avantaj sağlayabilir. Ayrıca Dİ’ler, e-ticaret işletmelerinin iş süreçlerini otomatikleştirerek verimliliği artırabilir ve operasyonel maliyetleri düşürebilirken, müşteri geri bildirimlerini analiz ederek ürün geliştirme süreçlerine değerli bilgiler sağlamakta ve yeni pazar fırsatları belirleyebilmektedirler. İyi tasarlanmış Dİ botları da, şirketlere rakiplerinden önce pazara yeni ürün ve hizmetler sunma avantajı sağlayabilir ve pazar payını genişleterek rekabet açısından şirketleri öne geçirebilir. Bu bakımdan çalışma, Dİ botlarının e-ticaretteki rekabet üzerindeki etkilerini anlamak için önemli bir bilgi kaynağı sağlamaktadır.
Dijital Oyun Bağımlılığı Olan Bireylerde Farkındalık Eğitiminin Ağrı, Kas Aktivitesi, Depresyon ve Uyku Kalitesine Etkisi
Authors: Açıkgöz Yusuf , Mustafaoğlu Rüstem
Published: December 2024

Çalışmanın amacı, dijital oyun bağımlılığının bireylerde boyun ağrısı, kas aktivite düzeyi, depresyon ve uyku kalitesi üzerine etkisini saptamaktır. Ayrıca, dört haftalık farkındalık eğitimin bu bireylerde boyun ağrısı, kas aktivite düzeyi, depresyon ve uyku kalitesi üzerine etkisini araştırmaktı. Çalışmaya Fizyoterapi ve Rehabilitasyon Anabilim Dalı’nda eğitim gören ve araştırmaya alınma kriterlerini karşılayan 30 gönüllü katılımcı dâhil edildi. Katılımcılar Üniversite Öğrencileri İçin Dijital Oyun Bağımlılığı Ölçeği’nden aldıkları puana göre Oyun bağımlı grubu (n= 15) ve Kontrol grubuna (n=15) ayrıldı. Katılımcılar demografik özellikleri ve dijital oyun oynama süreleri sorgulandı. Ayrıca katılımcıların ağrı şiddeti Vizüel Analog Skalası (VAS) ile, kas aktivasyonu Delsys 2 Kanallı Trigno Avanti Mobil elektromiyografi sistemi ile, depresyon düzeyleri Beck Depresyon Ölçeği (BDÖ) ile, uyku kalitesi ise Pittsburgh Uyku Kalitesi İndeksi (PUKİ) ile değerlendirildi. Oyun bağımlı grubunda yer alan katılımcılara haftada bir saat dört hafta çevrimiçi olarak farkındalık eğitimi verildi. Grupların karşılaştırılmasında sol ve sağ üst trapezius kas aktivitesi, VAS puanı, BDÖ skoru ve PUKİ skoru açısından istatistiksel olarak anlamlı bir fark saptanmadı (p>0,05).Oyun bağımlı grubun dört haftalık farkındalık eğitim sonrasında eğitim öncesine göre trapezius kas aktivitesinde, VAS puanında, BDÖ ve PUKİ skorlarında sayısal olarak gelişme gösterse de, bu gelişme istatistiksel olarak anlamlı değildi (p>0,05). Sonuç olarak, oyun bağımlı bireylerde üst trapezius kas aktivitesinde azalma, boyun ağrısı şiddetinde artış, depresyon düzeyinde artış ve uyku kalitesi azalma olduğu fakat bu farklılık normal bireylere göre anlamlı olmadığı görüldü. Oyun bağımlı bireylerde farkındalık eğitimi sonrasında üst trapezius kas aktivitesinde artış, boyun ağrısı şiddetinde azalma, depresyon düzeyinde azalma ve uyku kalitesinde artış olsa da bu gelişmeler anlamlı değildi.
Trends and Emerging Themes in Thermal Energy Storage: A Bibliometric Study
Authors: Karadağ Malik , Akçay İdris Tan , Karakurt Asım Sinan
Published: December 2024

Thermal energy storage (TES) systems play a pivotal role in the efficient integration of renewable energy sources into the global energy landscape. This bibliometric analysis delves into the evolving research landscape of TES systems, focusing on nearly 19000 scientific papers from the Scopus database as the primary source to identify key research trends, influential authors, and leading institutions shaping the field between 2000 and 2023. The analysis reveals a substantial surge in TES research over the past two decades due to factors such as advancing technology and increasing incentives. China has emerged as a global leader in this domain, followed closely by the United States and India. Xi'an Jiaotong University, De Lleida University, and Tsinghua University are the most prolific institutions in this field. The Journal of Energy Storage is the most frequently paper-published, followed by Applied Thermal Engineering and Applied Energy. Key research themes identified include the development, design, and optimization of heat storage systems, TES system integration with renewable energy sources, and the exploration of phase change materials for efficient energy storage. The analysis also highlights the contributions of prominent researchers in the field. Cabeza LF, Li Y, and Wang Y are identified as the most prolific authors, having made significant contributions to the advancement of TES technology. The increasing demand for sustainable and efficient energy solutions has spurred significant interest in TES systems. As the world transitions towards a low-carbon future, TES systems offer a promising solution for storing excess renewable energy and ensuring a reliable and sustainable energy supply.
‘Samourai’ Kesme Gül Çeşidinin Farklı Vazo Solüsyonlarıyla Vazo Ömrünün Uzatılması
Authors: Doğan Meral Ezgi , Kazaz Soner
Published: December 2024

Dünyada ticareti en fazla yapılan kesme çiçeklerin başında kesme gül yer almakta ve hem kıtalar içi hem de kıtalar arasında taşınmaktadır. Kesme güllerin vazo ömrü; iletim demetlerinin tıkanarak yeterli suyu çekememesi, boyun bükme, petallerde kararma ve solma, hastalık (özellikle kurşuni küf) vb. nedenlerle kısalmaktadır. Çiçeklerin vazo ömrü ise vazo solüsyonlarına ilave edilen koruyucu maddelerle uzatılabilmektedir. Çalışmada bitkisel materyal olarak Rosa hybrida türüne ait ülkemizde ticareti oldukça fazla yapılan kırmızı renkte çiçeklere sahip standart tip çiçekleri olan ‘Samourai’ çeşidi kullanılmıştır. Vazo solüsyonu olarak 4 farklı uygulama [ticari marka çamaşır suyu (%0.2, ACE: ürün bileşimi ˂5 Klor bazlı ağartıcı), Sodyum hipoklorit (75 mg L-1), Chrysal (%0.2) ve 8-hydroxyquinoline (200 mg L-1)] kullanılmış ve sonuçlar distile suyun kontrol olarak kullanıldığı uygulama ile karşılaştırılmıştır. Çalışmada; çiçeklerin vazo ömrü, toplam vazo solüsyon alımı, oransal taze ağırlık, vazo ömrü süresince petal rengi, çiçek çapı ve vazo solüsyonlarındaki pH ve EC değişimleri ile mikrobiyal aktivite incelenmiştir. Çalışmamız %0.2 Chrysal (17.83 gün), %0.2 çamaşır suyu (17.75 gün), 200 mg L-1 8-hydroxyquinoline (12.42 gün), 75 mg L-1 Sodyum hipoklorit (9.17 gün) içeren vazo solüsyonlarının, kontrol (8.0 gün)’e kıyasla çiçeklerin vazo ömrünü önemli ölçüde artırdığını göstermiştir. Sonuç olarak, piyasada ticari olarak kullanılan çamaşır suyunun, dünya kesme çiçek sektöründe ticari çiçek koruyucusu olarak kullanılan Chrysal ürünü kadar kesme gül çiçeklerinin vazo ömrünü uzattığı ve çiçek kalitesini koruduğu belirlenmiştir.
İKİ FARKLI AĞIR METALİN (BAKIR VE ÇİNKO) TIBBİ SÜLÜKLER (HİRUDO VERBANA) ÜZERİNE ETKİLERİNİN ARAŞTIRILMASI
Authors: Yılmaz Erdal , Atici Ebubekir
Published: December 2024

Araştırmada çinko ve bakır metallerinin farklı konsantrasyonlarının tıbbi sülükler üzerindeki etkileri incelenmiştir. 10 litrelik kaplara 15 adet olacak şekilde stoklanan tıbbi sülükler (Hirudo verbana) bakır ve çinko metallerinin letal dozların altında belirlenen farklı iki doza maruz bırakılmıştır. Çinko ve bakır için 96 saatlik muamele dozları sırası ile 3.0 mg/L ile 12 mg/L ve 0.15 mg/L ile 0.6 mg/L iken; 30 günlük muamelelerde 0.5 mg/L ile 2.0 mg/L ve 0.02 mg/L ile 0.08 mg/L olarak uygulanmıştır. Bu uygulamalardan sonra sülüklerden alınan salya örneklerinin antimikrobiyal karakteristiği, ağır metal birikimleri ve malondialdehyde (MDA) düzeyleri analiz edildi. Çalışmada balık patojenlerinden Lactococcus garviae ve Yersinia ruckeri’ ye karşı sülük salyasının herhangi bir antimikrobiyal etki göstermediği belirlenmiştir. Tıbbi sülüklerin çinko ve bakır metallerine maruz kaldıklarında dokularında depolanan ağır metal miktarlarının arttığı tespit edilmiştir. Ayrıca çinko ve bakırın farklı konsantrasyon ve sürelerde maruziyetinde sülük salyasında malondialdehit değerlerinin de artış gösterdiği bulunmuştur. Elde edilen verilerden Hirudo verbana türü tıbbi sülüğün çinko ve bakır ağır metalleri için iyi bir biyo-monitör organizma olduğu ortaya konulmuştur.
สารยับยั้งไลเปสจากผักเชียงดา
Authors:   , ศีลวัตรพงษ์ กมลชนก
Published: December 2024

ปัญหาภาวะอ้วนเป็นสาเหตุหนึ่งของการเกิดโรคเรื้อรังต่างๆ เพราะฉะนั้นการลดอัตราการเกิดโรคอ้วน จึงมีความสำคัญเป็นอย่างมาก หนึ่งในการรักษาโรคอ้วนด้วยการใช้ยาเป็นวิธีหนึ่งที่มีการใช้กัน โดยผลิตภัณฑ์ที่ได้การรับรองให้มีข้อบ่งใช้ในผู้ที่เป็นโรคอ้วนและสามารถจำหน่ายได้ตามร้านยาเพียงชนิดเดียวคือ Orlistat ซึ่งมีกลไกการออกฤทธิ์ยับยั้งเอนไซม์ pancreatic lipase ซึ่งมีหน้าที่ย่อยสลายไขมันจากอาหารที่อยู่ในรูปไตรกลีเซอไรด์ที่เป็นไขมันที่มีขนาดโมเลกุลใหญ่ให้กลายเป็นกรดไขมันกลีเซอรอลที่มีขนาดโมเลกุลเล็กลง ดังนั้นการค้นหาสารจากพืชสมุนไพรที่สามารถยับยั้งการทำงานของเอนไซม์นี้ได้จะทำให้การดูดซึมไขมันเข้าสู่ร่างกายลดลง
ผักเชียงดา หรือ Gymnema inodorum เป็นพืชในวงศ์ Asclepiadaceae มีสรรพคุณในการลดระดับน้ำตาลในเลือด โดยมีสารสำคัญที่เป็นตัวออกฤทธิ์ลดระดับน้ำตาลในเลือด คือ สารกลุ่ม gymnemic acids ซึ่งสามารถยับยั้งเอนไซม์ alpha-glucosidase ได้อย่างไรก็ตามพบว่ายังไม่เคยมีรายงานการวิจัยที่เกี่ยวข้องกับการยับยั้งเอนไซม์ pancreatic lipase ของผักเชียงดามาก่อน จากการศึกษาเบื้องต้นพบว่าสารสกัดหยาบชั้นเอทานอลของผักเชียงดาที่ความเข้มข้น 1 มิลลิกรัมต่อมิลลิลิตรสามารถยับยั้งเอนไซม์ pancreatic lipase ได้ปริมาณร้อยละ 75 ดังนั้นคณะผู้วิจัยจึงมีความสนใจที่จะศึกษาหาสารสำคัญที่เป็นตัวออกฤทธิ์ในผักเชียงดาโดยในการศึกษาครั้งนี้สามารถแยกสารบริสุทธิ์ได้ 1 ชนิดคือ GI1 (ดังรูป) และได้มีการพิสูจน์หาโครงสร้างของสารสกัดจากผักเชียงดาโดยเทคนิคทาง spectroscopy พร้อมทั้งเปรียบเทียบกับข้อมูลที่มีการรายงานมาก่อน อย่างไรก็ตามเมื่อนำสารชนิดดังกล่าวมาทดสอบพบว่า GI1 ไม่มีฤทธิ์ในการยับยั้งเอนไซม์ pancreatic lipase อีกครั้งเมื่อนำไปทดสอบฤทธิ์ต้านอนุมูลอิสระพบว่าสารดังกล่าวไม่มีฤทธิ์ต้านอนุมูลอิสระเช่นกัน
Perceived partner’s dissatisfaction with physical appearance and body image dissatisfaction : the moderating role of traditional attitudes toward gender role
Authors:   , Owassatit Teranart
Published: December 2024

Body image dissatisfaction has become a major problem in recent years, with the dissatisfaction being associated with disturbances in normal psychological functioning and eating disorders including bulimia (Birbeck & Drummond, 2003). With the pervasiveness of body image dissatisfaction and the costs associated, our study examined variables potentially linked to body image dissatisfaction in Thai female adolescents. Specifically, whether perceived partner perception was associated with body image dissatisfaction and whether this examination was moderated by attitude towards traditional gender role was examined. One hundred Thai female undergraduates completed measuring set of measures of body image dissatisfaction, perceived partner perception and attitudes toward gender roles. Results revealed that the participants’ perception of their partner dissatisfaction with their physical appearance and their endorsement towards traditional gender role were significantly and positively associated with body image dissatisfaction (r = .25, p < .01 and r = .17, p =. 05, respectively). However, attitudes toward gender roles was not significant in moderating the association between perceived partner perception and body image dissatisfaction (β =-.84, p =. 395). Possible explanations for the findings were outlined in relation to the Thai collectivistic culture and methodological consideration.
THE EFFECT OF PSYCHOLOGICAL CAPITAL ON WORK ENGAGEMENT WITH PERCEIVED CLAN TYPE ORGANIZATIONAL CULTURE AS A MODERATOR
Authors:   , Saengboon Jadejutha
Published: December 2024

This research study aims to examine the positive relationship between psychological capital (PsyCap) and work engagement as well as the moderation effect of perceived clan type organizational culture on the relationship between psychological capital and work engagement. The data were collected from 210 employees from different companies in Bangkok, Thailand. Data analysis was conducted using linear regression. The findings indicated that the effect of psychological capital and work engagement exists and perceived clan type organizational culture significantly moderates the relationship between the two variables.