bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Retaliasi, Budaya Organisasi, Dan Norma Subjektif Terhadap Whistleblowing Intention Pada Lembaga Perkreditan Desa Se-Kecamatan Mengwi
Authors: Suastini Ni Kadek Ayu , Yuniasih Ni Wayan , Windika Pratiwi Ni Putu Trisna
Published: October 2023

This study aims for determine the effect of retaliation, organizational culture, and subjective norms on whistleblowing intentions in LPDs throughout the Mengwi District. The population in this study were all LPD employees in Mengwi District, totaling 306 people (Badung Regency LPLPD, 2022). The number of LPDs in Mengwi District is 38 LPDs with a total 75 Samples. Technique Data analysis using linear regression analysis. The results of the study show that Retaliation has a negative effect on whistleblowing intentions at LPDs throughout the Mengwi District. Organizational culture has a positive effect on whistleblowing intentions in LPDs throughout the Mengwi District. Subjective norms have a positive effect on whistleblowing intentions in LPDs throughout the Mengwi District.
The Development of Digital Comic for Al-Quran and Al-Sunnah Education Subject
Authors: Mohd Zainadi Norazlin Amira , Ismail Roesnita
Published: October 2023

Abstract: With the development of current digitization and the Covid-19 pandemic, these have forced teachers to carry out the online learning activities. However, the traditional learning activities using printed textbooks might make students disinterested in paying attention for the subject, especially during the online learning. The development of digital comic as teaching and learn-ing tools was plenty, however this research aims to focused on the development of the digital comic of Pengajian Hadith in the Al-Quran and Sunnah Education (PQS) subject, which is a printed textbook was converted into a digital comic to be a solution to help and motivate stu-dents in learning of this subject because the digital comic has more interactive features that is easy to remember, understand. Besides that, the digital comic developed aim to be a solution that can be accessed anywhere, anytime and more enjoyable. This research focused on the de-velopment of the digital comic of Form Five Ibnu Rusyd students from Sekolah Menengah Agama AL-Ihsan, Kuantan Pahang based on the topic of PQS textbook to support the online learning during the Covid-19 pandemic. The development of the digital comic based on the A.D.D.I.E model. It is hope that the proposed digital comic will be suitable to be used and in-crease the students’ interest in learning the Al-Quran and Sunnah Education (PQS) subject.
 
Abstrak: Dengan perkembangan pendigitalan masa kini dan pandemik Covid-19, telah me-maksa para guru untuk melaksanakan aktiviti pembelajaran secara dalam talian. Walau bagaimanapun, aktiviti pembelajaran menggunakan medium seperti buku teks mungkin me-nyebabkan pelajar tidak berminat untuk memberi perhatian kepada bahan yang disediakan teru-tamanya semasa pembelajaran dalam talian. Perkembangan komik digital dalam mata pelajaran akademik sememangnya banyak, tetapi kajian ini menumpukan kepada pembangunan komik digital bagi mata pelajaran PQS, iaitu buku teks bercetak yang ditukar kepada komik digital. Ia menjadi penyelesaian dalam membantu dan memotivasikan pelajar bagi pembelajaran subjek ini kerana komik digital mempunyai bahasa yang mudah difahami, diingat serta sangat menarik. Selain itu, komik digital yang dibangunkan bertujuan untuk menjadi penyelesaian yang boleh diakses di mana-mana, bila-bila masa dan lebih menyeronokkan. ini tertumpu kepada pem-bangunan komik digital pelajar Tingkatan Lima Ibnu Rusyd dari Sekolah Menengah Agama AL-Ihsan, Kuantan Pahang berdasarkan topik Pengajian Hadith yang terdapat dalam buku teks Pendidikan Al-Quran dan Sunnah (PQS) bagi menyokong pembelajaran dalam talian se-masa pandemik Covid-19. Kajian ini tertumpu kepada pembangunan komik digital berdasarkan model A.D.D.I.E. Komik digital yang dicadangkan ini diharap sesuai digunakan dan dapat meningkatkan minat pelajar terhadap mata pelajaran Pendidikan Al-Quran dan Sunnah (PQS).
Task-Based Language Teaching (TBLT): Exploring EFL Learners Peer Interaction Engagement
Authors: Baharun Hazleena , Harun Haliza , Abdullah Hazlina , Zakaria Zulkarnin , Zakaria Zarina Ashikin , Mat Saad Noor Saazai
Published: October 2023

Abstract: This study aimed to explore peer group interaction of learners when engaged in collaborative tasks. Eighteen gifted EFL learners aged 14 from an intact class were the participants of the study. The learners were grouped in groups of three and their oral interactions when they engaged in given collaborative tasks taken from their textbook were audio-recorded and transcribed verbatim. Focusing on the dynamics of peer group interaction and learning, this study used a descriptive system of analysis of peer group interaction to analyse the kinds of peer group interactions generated by the participants as they approached and processed the collaborative tasks given to them. Two main dimensions - cognitive processing and social processing - were explored. The qualitative analysis of the recorded interaction revealed that the learner interactions of the participants were very exploratory in nature when they approached and processed the tasks. This exploratory nature of the learner interactions was very much characterised by intensive negotiation. They were also highly argumentative yet collaborative. The article concludes with a discussion on pedagogical implications generated from these findings.
 
Abstrak: Kajian ini bertujuan untuk meneroka interaksi pelajar apabila terlibat dalam tugas kolaboratif. Lapan belas pelajar EFL berumur 14 tahun dari kelas satu kelas adalah peserta kajian. Para pelajar dikumpulkan dalam kumpulan tiga dan interaksi lisan mereka apabila mereka terlibat dalam tugas kolaboratif yang diambil dari buku teks mereka telah dirakam audio dan ditranskripsikan verbatim. Memberi tumpuan kepada dinamik interaksi dan pembelajaran kumpulan rakan sebaya, kajian ini menggunakan sistem deskriptif analisis untuk menganalisis jenis interaksi kumpulan yang dihasilkan oleh peserta ketika mereka mendekati dan memproses tugas kolaboratif yang diberikan kepada mereka. Dua dimensi utama - pemprosesan kognitif dan pemprosesan sosial - telah diterokai. Analisis kualitatif interaksi yang direkodkan mendedahkan bahawa interaksi para peserta sangat bersifat penerokaan ketika mereka mendekati dan memproses tugas. Sifat penerokaan interaksi pelajar ini sangat berbentuk rundingan intensif. Mereka juga berdebat namun kolaboratif. Artikel ini menyimpulkan dengan perbincangan mengenai implikasi pedagogi yang dihasilkan daripada penemuan ini.
The Contribution of Shaykh Abbas Kuta Karang in Malay Medical: A Study on Al-Rahmah fi Al-Tib wa Al-Hikmah Manuscript
Authors: Ibrahim Norhasnira
Published: October 2023

Abstrak: Malay scholars had played a significant role in the Malay Archipelago's Islamization. Shaykh Abbas Kuta Karang is well-known in Aceh, Indonesia, as a 19th-century Malay scholar, religious figure, astronomer, warrior, and medicinal expert. His well-known Malay medical manuscript titled Al-Rahmah fi al-Tib wa al-Hikmah is one of his masterworks. It is one of the most important references for Malay medical practitioners. The paper objectives to (i) highlight a biography of Shaykh Abbas Kuta Karang and (ii) describe the writing methodology of the medical knowledge documented in this manuscript. This study employed a qualitative methodology and was conducted in the mode of library research. This study's data was collected from the manuscript, books, journals, and previous studies. Medical knowledge in Al-Rahmah fi al-Tib wa al-Hikmah consists of five chapters beginning with human anatomy (based on fire, wind, water, and soil fundamentals), types of food and medicine (grain, milk, meat, and fruit), preventive healthcare (healthy eating, drinking habit, body movements, and others), types, causes, and treatments for certain illnesses (hair loss, migraine, freckles, earache, tooth ache, and others), and types, causes, and treatments for general illnesses (fever, vertigo, stroke, semi paralysis, and many more).
 
Abstract: Para cendekiawan Melayu telah memainkan peranan yang penting dalam proses penyebaran agama Islam di Alam Melayu. Di Aceh, Indonesia, Shaykh Abbas Kuta Karang terkenal sebagai seorang cendekiawan Melayu, ulama, ahli astronomi, pahlawan dan pakar perubatan pada abad ke-19 Masihi. Manuskrip Al-Rahmah fi al-Tib wa al-Hikmah merupakan satu karya dalam bidang perubatan Melayu yang telah dihasilkan oleh beliau. Ia sangat terkenal dan dijadikan rujukan oleh para pengamal perubatan Melayu. Objektif kajian ini ialah untuk (i) mengkaji biografi Shaykh Abbas Kuta Karang, dan (ii) menghuraikan metodologi penulisan ilmu perubatan Melayu yang dicatat dalam manuskrip tersebut. Metodologi kualitatif telah diaplikasikan dalam kajian ini dan ia adalah berbentuk kajian kepustakaan. Data kajian diperolehi daripada manuskrip, buku-buku, jurnal, dan kajian terdahulu yang berkaitan. Dapatan kajian menunjukkan bahawa ilmu perubatan Melayu yang dibincangkan dalam Al-Rahmah fi al-Tib wa al-Hikmah terdiri daripada lima bab bermula dengan anatomi manusia (berdasarkan unsur api, angin, air dan tanah), jenis makanan dan ubatan (bijirin, susu, daging dan buah-buahan), penjagaan kesihatan dan pencegahan penyakit (kaedah pemakanan yang sihat, tabiat minum, pergerakan badan dan lain-lain), jenis, punca dan rawatan bagi penyakit khusus (rambut gugur, migrain, jeragat, sakit telinga, sakit gigi dan lain-lain) serta jenis, punca dan rawatan bagi penyakit umum (demam, vertigo, strok, separa lumpuh dan banyak lagi.)
Knowledge on Oral Hygiene Maintenance of Children Aged 6 to 9 Years Attending at the OPD of a Tertiary Care Dental Hospital in Dhaka City
Authors: Alam Md Shafiul , Shahed Abu Mohammad , Mesbah Fahmida Binte , Haque Mohammad Ahtashamul , Azam Md Shafiul , Mian Md Anower Hussain
Published: October 2023

Background: Knowledge from pre-primary school about the prevention of dental caries is better before the disease process has starte.
Objective: The purpose of this study was to observe the knowledge of oral health maintenance among the children of 6 to 9 years old such as regular tooth brushing, uses of oral hygiene aids and dental attendance to maintain their good oral health for a life time.
Methodology: This cross-sectional study conducted in Dhaka Dental College and Hospital, Bangladesh study was carried out from October 2019 to September 2020. A total of 175 participants children aged 6-9 years attending at the OPD with dental Caries in Dhaka Dental College Hospital were the study population. The study population were Included Children aged 6 to 9 years in Dhaka dental college and hospital who were available and wished to participate. The questionnaire was used in this study pre-tested before the data collection, data was collected using semi-structured questionnaire by face-to-face interview.
Results: A total of 175 participants children aged 6 to 9 years attending at the OPD with dental Caries in Dhaka Dental College Hospital were the study population. The knowledge according to the correct method of tooth brushing to keep healthy teeth which were significant with their age and education. The study revealed the knowledge according to the correct method of tooth brushing to keep healthy teeth which were not significant among both gender (P=0.000038) and level of education (P=0.00001). The knowledge according to cleaning teeth and mouth after each meal to keep healthy teeth which were significant only with their age (P=0.00027) and same as knowledge according the to relation of food or drinks with healthy teeth which were significant with their age(P=0 .00729) and education significant level (P=0.001185), the knowledge according to poor oral health causes of dental problem which were significant with their education level (P=0.002524) and knowledge to the necessity of dental check-up at least once in year which were significant with their age(P=0.04237) and education level (P=0.002524).
Conclusion: In conclusion, it is found that a significant association between the education level and age of children have good knowledge of oral health hygiene to prevent dental caries among the young children who are more prone to develop the diseases.
Bangladesh Journal of Medical Microbiology, January 2023;17 (1):15-20
Gender and Age Dependent Bacteriological Etiology of Community-Acquired Blood Stream Infection
Authors: Rashid Nafisa , Shaha Ritu , Rahman Md Mahbubur , Maya Nasrin Akhter , Hosna Asma Ul
Published: October 2023

Background: Bloodstream infection constitutes one of the most serious situations in infectious disease.
Objective: The purpose of the presents study was to determine the gender and age dependent etiology of community- acquired urinary blood stream infection.
Methodology: This was a retrospective analysis of blood samples from clinically suspected cases of blood stream infection. Samples were collected at Ad-din Women’s Medical College Hospital, Dhaka & Rushmono Specialized Hospital, Dhaka from January 2018 to September 2018. All the samples were collected from inpatient’s and outpatient’s department of our hospital during the study period and processed in Microbiology laboratory. The BD BACTEC FX40 automated blood culture method was used to isolate bacterial pathogens and antimicrobial susceptibility test was performed by Kirby-Bauer disc diffusion method.
Results: A total of 483 (16.1%) pathogens were isolated from 3018 bacteremia suspect patient blood specimens. Gram-negative cocci (58.4%) were predominant organisms recovered followed by Gram-positive bacilli (41.6%). Majority of BSI were caused by Gram negative bacteria predominantly Salmonella Typhi (31.1%). Salmonella species was found less prevalent in the children (55%) and more frequent in the age groups 16 to 30 years (85.0%) and more than 60 years (100.0%). Acinetobacter species was found less prevalent in age group 16 to 30 years (7.5%). Escherichia coli was found only few prevalent in the 1 to 15 (0.5%) and higher frequent in the age groups 16 to 30 years (2.5%). Salmonella species isolates appeared to be sensitive to ceftriaxone (91.3%), meropenem (90.7%) and cotrimoxazole (76%). Sensitivity rates of ciprofloxacin, gentamycin and levofloxacin were 87.3% for coagulase-negative Staphylococcus species (CoNS).
Conclusion: Both patients’ age and gender are significant factors in determining bloodstream infection.
Bangladesh Journal of Medical Microbiology, January 2023;17(1):3-9
Scope of Development of Vaccine against Antibiotic Resistant Klebsiella pneumoniae: Current Perspective
Authors: Chowdhury Md Zaforullah
Published: October 2023

Abstract Not Available
Bangladesh Journal of Medical Microbiology, January 2023;17(1):1-2
Farmers’perception of veterinary services in Bangladesh
Authors: Paul AK , Aziz T , Biswas S
Published: October 2023

Farmers’ perception of veterinary services at the Upazila (Sub-district) Veterinary Hospital (UVH), and constraints of livestock farming in Bangladesh were studied. Data from 135 livestock farmers which were obtained, using a pretested questionnaire. Most of the farmers (99.3%) had small families. Most were illiterate (60.0%), 22.2% had Secondary School Certificate and 17% had Higher Secondary Certificate or above. Mostly, stall feeding system was practised (76.9%), concentrated feed (71.9%) and water (68.9%) were supplied twice daily and animals were dewormed at regular intervals (51.1%). Irregular vaccinations were followed by 15.6% farmers. Only 55.2% of farmers called on veterinary surgeons when their animals were sick. About 77.6% farmers were satisfied with the existing public veterinary services.About 32.1% farmers got veterinary services at their door step by the veterinary surgeons whereas 29.9, 28.4 and 8.2% farmers received drugs, services, and free vaccination, respectively. Poor knowledge of farming (71.3%), feeds and fodder scarcity (55.6%) and unavailability of safe water (64.4%) were the main constraints identified. It is suggested that more training and veterinary extension programmes for farmers are required.
Bangl. vet. 2022. Vol. 39, No. 1-2, 26–33
Influence of age on haematological and biochemical blood profiles of black Bengal goats (Capra hircus)
Authors: Samaddar K , Haque Z , Rahman MM
Published: October 2023

The study was conducted to know the effects of age on haemato-biochemical profiles in Black Bengal (BB) goats. Fifty BB goats were equally divided into five groups: group A (control, 3 years), group B (>3 - 5 years), group C (2-<3 years), group D (1-<2 years) and group E (<1 year). Most of these haemato-biochemical parameters were within the normal range of reference values, except Albumin and ALP. The significantly (P<0.01) higher concentrations of RBC (17.9 ± 0.2 Million/cu mm), WBC (14.4 ± 0.3 Thousands/cu mm), Haemoglobin (9.0 ± 0.2 gm/dl) and PCV (29.9 ± 0.2%) were found in group B. The percentage of Neutrophil (35.2 ± 0.4%), Eosinophil (1.0 ± 0.0%) and Basophil (0.6 ± 0.0%) were higher in group E. Percentage of Lymphocyte (60.0 ± 0.4 %) and Monocyte (3.5 ± 0.2%) was higher in group B than other younger groups. The significantly (P<0.05 and P<0.01) higher concentration of total protein (74.7 ± 0.2g/L) and globulin (46.3 ± 0.5 g/L) respectively, were in Group B. Albumin (28.4 ± 0.2g/L) and ALT (22.3 ± 0.5 U/L) concentrations were significantly P<0.02) higher in Group E than other groups of goat.

Bangl. vet. 2022. Vol. 39, No. 1-2, 43–53
Pulmonary Atresia (PA) with Anomalous Origin of the Pulmonary Artery
Authors: Jubada Razina , Khaleda Parvin Rekha  , Md Mofazzal Sharif  , S M Aftab-E-Alam
Published: October 2023

Pulmonary atresia with ventricular septal defect is a severe form of congenital cyanotic heart disease (TOF) but its not very common form. Here main pulmonary does not arises from common arterial trunk. In pulmonary atresia there is no proper formation ofthe pulmonary valve which allows blood from the heart to thelung of patient. Instead of opening and closing of the valve,a solid sheet of tissue develops. Therefore blood cannot flow by its normal path to take oxygen from the lung. Instead, inadequate blood travels to the lung through other natural routes within the heart and its arteries and presenting degree of pulmonary atresia or discontinuity in arteries. MDCT gave structural details in this regard. So, role of MDCT play an important role to evaluate the details important information needed in preoperative evaluation for surgical policy in atretic patients. Here we discuss a case of pulmonary atresia (PA) with anomalous origin of the pulmonary artery.KYAMC Journal Vol. 14, No. 02, July 2023: 102-104.
Alarming Trends of Dengue in 2023
Authors: Moniruddin A B M
Published: October 2023

Abstract not available
KYAMC Journal Vol. 14, No. 02, July 2023: 62-63.
Satisfactory Improvement in Lifestyle of a Spastic Quadriplegic Cerebral Palsy Patient through Cranial Surgery
Authors: Md Faridul Islam Chowdhury
Published: October 2023

Several treatment options may help improve daily functioning in children with cerebral palsy (CP). However, these treatments cannot prevent early death or enable them to lead independent life without support. CP is a progressive disease, and even in its milder form, conditions such as Parkinson's disease, epilepsy, and stroke may develop even after 25 years. A new era of curable treatment has emerged for CP, utilizing bilateral cranioplasty and duraplasty (Tanfarid Procedure). This case report describes a successful case where this procedure was employed. During the surgery, after the removal of cranial bones through craniotomy, the absence of dural pulsation was observed, indicating elevated intracranial pressure. After duraplasty, normal brain pulsation was observed, indicating that intracranial pressure had normalized. In patients with CP, premature closure of sutures and thickening of skull bones lead to a reduced intracranial volume, which hinders proper brain growth and eventually results in brain atrophy, widened Sylvian issures, and widened sulci accompanied by the loss of brain parenchymal tissue. These findings were also evident in the patient's brain CT scan. In this case, cranioplasty and duraplasty provided adequate space for the brain to grow . The treatment of CP patients typically involves a multidisciplinary approach, which can be expensive. However, the procedure utilized in this case is affordable for economically disadvantaged individuals in this country. While a second cranial surgery may be required in some cases, the expenses associated with it are significantly lower compared to a lifetime of physiotherapy and other supportive treatments. Additionally, the outcomes are very promising.KYAMC Journal Vol. 14, No. 02, July 2023: 105-108.
The Role of Religiousity in Mitigating the Effects of Technostress on Engaging Academic Fraud during Accounting Online Learning
Authors: Priyastiwi  , Sriwidharmanely  , Abdul Halim
Published: October 2023

The aim of this study is to examine how religion may help students overcome the effects of technostress, which heightens students' propensity for academic dishonesty during online learning.  First, this study uses the self-determination theory (SDT) to describe the function of religion.  We confirm that student’s technostress increases academic fraud during online learning using structural equation modelling (SEM).  The study concludes that during hybrid learning, students with strong religiosity are more intrinsically motivated to prevent academic fraud than are students with low motivation. Students must be extremely motivated, confident in their cognitive flow, and convinced that using ICT won't cause them to engage in dysfunctional behavior in order to successfully adopt a virtual face-to-face application or learning management system in education.  The study's last finding is that students' cognition can boost their positive emotion.
First-line tepotinib for a very elderly patient with metastatic NSCLC harboring MET exon 14 skipping mutation and high PD-L1 expression
Authors: Inno Alessandro , Bogina Giuseppe , Settanni Giulio , Salgarello Matteo , Foti Giovanni , Pomari Carlo , Picece Vincenzo , Gori Stefania
Published: October 2023

Optimal treatment for metastatic non-small cell lung cancer (NSCLC) with mesenchymal epithelial transition gene (MET) exon 14 skipping mutation has not been established yet. MET inhibitors were demonstrated to be effective and tolerated in patients with this condition, while evidence on safety and efficacy of immunotherapy and/or chemotherapy in this population is limited. Here we report the case of an 86-year-old male with metastatic NSCLC harboring MET exon 14 skipping mutation and with high programmed cell death ligand 1 (PD-L1) expression (tumor proportion score ≥50%). The patient received the MET inhibitor tepotinib as first-line treatment, achieving a partial response, with G2 peripheral edema as adverse event that was successfully managed with temporary discontinuation, dose reduction, diuretics and physical therapy. After 31 months, the patient is still receiving tepotinib, with an ongoing response. Tepotinib is a valuable therapeutic option for first-line treatment of older patients with NSCLC harboring MET exon 14 skipping mutation, even in the presence of high PD-L1 expression.
Shaping the Future of Coronary Interventions by Highlighting Coronary Anatomy and Reducing Contrast Volume
Authors: Kirtane Ajay , Escaned Javier , Messenger John , Danenberg Haim , Strobel Aaron
Published: October 2023

Coronary interventions, and specifically the number of percutaneous coronary intervention (PCI) procedures, are increasing, together with their complexity. Contrast media administration during those procedures assists in visualising vessels anatomy, but also increases the risk of contrast-induced nephropathy (CIN), which remains one of the most common complications, and has been associated with poor clinical outcomes.

Dynamic Coronary Roadmap (DCR) is a technology that creates a dynamic, motion-compensated, real-time view of the coronary anatomy overlaid on a 2D fluoroscopic image, creating a coloured map that adjusts automatically, and providing continuous visual feedback on the positioning of wires and catheters.

The technology, which is already being used in clinical practice, has posed the promise of not only assisting in navigating wires and catheters, but also reducing the use of contrast during PCI.

DCR4Contrast was a randomised clinical trial conducted in the USA, Europe, and Israel that enrolled more than 356 patients. The primary endpoint for the study was the reduction in contrast administered with the use of DCR, compared with the control group. The secondary endpoint was the potential reduction in the number of cineangiography runs.

In the trial, DCR reduced the total contrast volume per PCI procedure by an average of 28.8%, and reduced the number of contrast-enhanced cineangiography runs per procedure by 26.3%.

It was also demonstrated that the more complex the PCI procedure, the larger the reduction in contrast with DCR.

Here, interventional cardiology experts discussed the need for contrast reduction, and the evidence for DCR.
Hypertonia és nefroprotekció időskorban
Authors: Dolgos Szilveszter , Huszár Liliána
Published: October 2023

Az idősebb korosztály aránya és életkilátása fokozatosan növekszik társadalmunkon belül, ráadásul ebben az életszakaszban a hypertonia és a csökkent veseműködés előfordulási gyakorisága már meghaladhatja a 60%-ot. Közleményünkben ismertetni szeretnénk a hypertonia és a krónikus vesebetegség (chronic kidney disease, CKD) kapcsolatának és adekvát kezelésének fontosságát, hangsúlyozva a CKD korai felismerésére és kezelésére vonatkozó szakmai megfontolásokat, mindezt úgy, hogy az idősödő populáció speciális tulajdonságait is szem előtt tartjuk, mind a prevenció, mind a terápia tekintetében. Hiszen az előrehaladott korú betegeknél az általános halálozási kockázat is magasabb, különösen, ha az idős betegnek CKD-ja is van, ami olyan mértékben növelheti a cardiovascularis (CV) kockázatot, hogy a vesebetegeknek csak kis hányada éri el a végstádiumú vesebetegséget (ESRD), mivel korábban meghalnak CV szövődményekben, mint kialakulhatna a definitív végstádiumú veseelégtelenség, illetve a vesepótló kezelés bevezetésének a szükségessége. Összegezve tehát egy hypertoniás, CKD-ban szenvedő betegnél a cardiovascularis kockázat patogenezise komplex és a CV rizikó jelentősen fokozott, ami fokozott körültekintést és éberséget kíván a kezelőorvostól az idős vesebetegek holisztikus gondozása során.
BIST-100 ENDEKSİNDE İŞLEM GÖREN MEVDUAT BANKALARININ FİNANSAL PERFORMANSLARININ İNCELENMESİ
Authors: ER Hülya
Published: October 2023

Bankacılık sektörü finans sektörünün en önemli yapı taşlarından birisi olup ülke ekonomisi için de değerli katkılar sunmaktadır. Bankacılık sektöründe yer alan güçlü bankaların finansal performanslarının incelenmesi, ekonomik büyümeyi teşvik etmek ve finansal istikrarı artırmak için önemlidir. Bu çalışmada, BIST-100 endeksinde işlem gören mevduat bankalarının finansal performanslarını etkileyen faktörler incelenmektedir. Çalışmada nicel analiz yöntemi tercih edilmiş olup, 2012-2022 yılları arasını kapsayan verilerin analizi için regresyon ve korelasyon testleri uygulanmıştır. Korelasyon analizi sonuçlarına göre, enflasyon ve GSYİH değişkenleri ile bankaların finansal performansları arasındaki ilişkiler istatistiksel olarak anlamlı bulunmuştur. Genelleştirilmiş Lineer Model (Logit) analiz sonuçlarına göre, enflasyon üzerinde Sermaye Yeterlilik Oranı, Toplam Krediler/Toplam Varlıklar, Toplam Krediler/Toplam Mevduat, Ortalama Aktif Kârlılık ve Ortalama Öz Kaynak Kârlılığı değişkenlerinin ve GSYİH üzerinde Toplam Krediler/Toplam Varlıklar ve Likit Aktifler/Toplam Aktifler değişkenlerinin istatistiksel olarak anlamlı olduğu görülmüştür. Bu çalışma ile makroekonomik koşulların bankaların finansal performans üzerindeki etkilerini anlamak ve değerlendirmek maksatlarıyla literatüre katkı sunulması hedeflenmektedir.
A proposed simplified scorecard for the linear descriptive evaluation of dairy characters of female camels (Camelus dromedarius) of the Majaheem breed
Authors: Dioli Maurizio , Nasef Mostafa , Braithwaite Bruce James , Rehman Umar
Published: October 2023

The camel (Camelus dromedarius) holds significant importance as a valuable livestock species for milk production. Consequently, there is an increasing need to enhance attitudes toward increasing camel milk production by selectively breeding camels with desirable milk production attributes. The Majaheem camels have gained recognition for their favorable milk production traits. However, there is currently a lack of rational and modern tools to aid in the evaluation of Majaheem camels, specifically in terms of their milk production capabilities. To address this deficiency and provide guidance to camel breeders for the effective evaluation and selection of superior milk-producing Majaheem camels, a breed linear scorecard is proposed in line with that adopted for Holstein–Friesian milking cattle. However, the scorecard has been simplified and adapted to the phenotypic characteristics of the Majaheem camel breed.
Evaluation of black soldier fly larvae meal as a functional feed ingredient in Atlantic salmon (Salmo salar) under farm-like conditions
Authors: Radhakrishnan Gopika , Liland Nina S. , Koch Marianne Wethe , Lock Erik-Jan , Philip Antony Jesu Prabhu , Belghit Ikram
Published: October 2023

Atlantic salmon (Salmo salar) were fed diets containing black soldier fly larvae (BSFL) meal at two inclusion levels for 13 months in open sea-cages. BSFL meal replaced plant-based ingredients and dietary insect meal inclusion levels were at 5% and 10%. A commercial salmon diet was fed as a control diet. Fish were reared from ~173 g to ~ 4 kg and were randomly distributed into nine open sea-cages with ~6000 salmon/cage (12×12 m2; 1900 m3). Fish from the sea-cages were sampled at two time points (mid and final samplings) to study the dietary effects of BSFL meal on the general health and welfare. Monthly assessments of sea-lice and gill score were conducted to evaluate the overall well-being of the salmon. The findings from the current study revealed that dietary inclusion of BSFL meal up to 10% did not have any significant effects in general growth, welfare or survival. However, significant positive response was observed in the general skin mucosal, hematological, and gene expression profiles of salmon. Notably, the group of salmon fed with 5% BSFL meal showed a significant decrease in plasma aspartate transaminase and alanine transaminase. Also, a significantly higher expression of interleukin1β in both skin and gill along with upregulation of matrix metallopeptidase9 and mucin18 in gill were observed in salmon fed BSFL at 5%, which aided in increased immune responses. Apart from that, this group had significantly higher mucus secretions, decreased cortisol response and increased number of erythrocytes. Furthermore, the delousing stress had a significant effect on the plasma cortisol, and these responses were independent of the dietary effect. Moreover, these immune responses behaved differently at different fish size and time points, acknowledging the influence of various factors in immune modulation. Overall, the findings from this study showed the effects of dietary BSFL meal to modulate the immune status of salmon. This study aims to fill the existing knowledge gaps regarding the impact of incorporating BSFL meal as a functional feed ingredient into the salmon diet on health and immune status replicating real farm conditions.
Magma storage conditions beneath Krakatau, Indonesia: insight from geochemistry and rock magnetism studies
Authors: Pratama Aditya , Nurfiani Dini , Suryanata Putu Billy , Ismail Taufik , Bunga Naen Gabriela Nogo Retnaningtyas , Abdurrachman Mirzam , Supriyadi Banggur Wilfridus Ferdinando , Asri Nining Sumawati , Nareswari Ratika Benita , Bijaksana Satria , Hanif Muhammad , Kriswati Estu , Kurniawan Idham Andri , Setiawan Nugroho Imam
Published: October 2023

Understanding the evolution of magma storage conditions on volcanoes which have had more than one caldera-forming eruption (CFE) is important to know about past and present conditions, as a key to forecast future potential hazards. Krakatau volcano is characterized by cyclic phases of growth and destruction of the edifice. A volcanostratigraphic study identified three eruptive periods: Old Krakatau, Young Krakatau, and Anak Krakatau. The Old and Young Krakatau periods ended with the first and second CFE respectively. Due to its permanent activity and edifice evolution, Krakatau poses a high risk on the surrounding inhabited islands. In this study, we combined geochemistry, rock magnetic, and petrology to infer the evolution of magma storage conditions from Old to Anak Krakatau periods. This study is the first to report on the chemical and rock magnetic characteristics, as well as storage system conditions of Old Krakatau and its relation to the ongoing evolution of Krakatau. Our data show that: 1) Old and Young Krakatau magma storage regions are shallow (within the upper 3 km), contain more differentiated magmas, from which the Old Krakatau magmas may be less oxidized and had lower temperatures than Young Krakatau; 2) Anak Krakatau magma storage is deeper (up to 26 km), less differentiated, and erupted hotter but more reduced compared to Old and Young Krakatau. The Old and Young Krakatau lavas were the products of pre-CFE and their chemical characteristics are included at maturation phase, whereas the Young Krakatau pumice samples were the product of the second CFE. Lastly, the post-second CFE activity of AK is currently in an incubation phase and represented by mafic products of frequent and small eruptions. Knowing that the volcano has experienced maturation and CFE phases in the past, the current AK may evolve to those phases in the future.
Chronology and geochemistry of Late Carboniferous volcanics in Bogda, Xinjiang: implications for the tectonic evolution of the Eastern Tianshan
Authors: Wang Wen-Jia , He Yu-Li , Xu Lei , Xu Wen-Bo , Ren Wen-Xiu , Wang Huai-Tao
Published: October 2023

The Late Carboniferous volcanic magmatic evolution in the Bogda Orogenic Belt is considerably important for understanding the evolution history of the Eastern Tianshan in the Central Asian Orogenic Belt. Our study focuses on the Upper Carboniferous Liushugou Formation in the Liudaogou and Qidaogou sections of Xishan Township in eastern Bogda. By analyzing the volcanics and sedimentary sequences, we present paleontological evidence, new zircon U–Pb ages, and geochemical data of the volcanics. The lithological composition of volcanics ranges from basic to acidic. The rhyolite has an age of 311.2 ± 1.7 Ma, which, when combined with guide fossils Plerophyllum sp., Zaphrentoides sp., and Zaphrentites sp., indicates its formation in the Late Carboniferous. The geochemical and zircon Lu–Hf isotopic data (εHf(t) = 8.0–11.9) indicate that the basalts originated from a metasomatized subcontinental lithospheric mantle, while andesites and rhyolites were products of crystallization differentiation of the basalts that underwent assimilative mixing. Based on the published data, we propose that the tectonic evolution, transitioning from island arc magmatic systems to post-collisional orogenic belts, commenced in the Bogda Orogenic Belt toward the end of the Late Carboniferous.
Peripheral blood lipid and liver and kidney function test results in long-term night shift nurses: a cross-sectional study in South China
Authors: Zhao Yang , Lu Xunhao , Wang Yanghua , Cheng Yiyi , He Qiao , Qin Rongqi , Li Wenrui , Liu Haizhou , Liu Yuanfang
Published: October 2023

Purpose

This study aimed to elucidate the effects of long-term day and night shifts on liver function and lipid metabolism in a group of nurses.

Methods

This cross-sectional study in December 2019 was based on a group of nurses. A total of 1,253 physically healthy caregivers were included, including 1231 women and 22 men. A total of 886 nurses had long-term shift work (working in a rotating system for >1 year). The receiver operating characteristic (ROC) curve and logistic regression analyses were used to evaluate factors related to long-term shift work.

Results

We observed differences in liver and kidney indicators between the non-night and night shift groups. The ROC curve revealed that CHO (AUC: 62.4%), LDLC (AUC: 62%), and GLUO (AUC: 61.5%) were more related to the night shift. Logistic regression analysis showed that night shift work was associated significantly with CREA (log (OR) = −0.02, 95% CI: −0.04 to −0.01), CHO (log (OR) = −0.38, 95% CI: −0.67 to −0.09), and GLUO (log (OR) = −0.35, 95% CI: −0.56 to −0.17). This correlation was observed only for CHO and LDHC (CHO: log (OR) = −0.55, 95% CI: −0.98 to −0.12; LDLC: log (OR) = 0.83, 95% CI: 0.32, 1.4) after age standardization. After using propensity score matching, we did not find evidence to support that the indicators differed between night and non-night shift groups.

Conclusion

Our study observed an association of long-term night work with abnormal liver and kidney function and dyslipidemia, but the difference was not significant after strict age matching. Although these findings may support interventions for long-term night shift nurses, more detailed studies are needed to confirm.
Role of glycolysis in inflammatory bowel disease and its associated colorectal cancer
Authors: Xia Yuxuan , Zhang Li , Ocansey Dickson Kofi Wiredu , Tu Qiang , Mao Fei , Sheng Xiumei
Published: October 2023

Inflammatory bowel disease (IBD) has been referred to as the “green cancer,” and its progression to colorectal cancer (CRC) poses a significant challenge for the medical community. A common factor in their development is glycolysis, a crucial metabolic mechanism of living organisms, which is also involved in other diseases. In IBD, glycolysis affects gastrointestinal components such as the intestinal microbiota, mucosal barrier function, and the immune system, including macrophages, dendritic cells, T cells, and neutrophils, while in CRC, it is linked to various pathways, such as phosphatidylinositol-3-kinase (PI3K)/AKT, AMP-activated protein kinase (AMPK), mammalian target of rapamycin (mTOR), and transcription factors such as p53, Hypoxia-inducible factor (HIF), and c-Myc. Thus, a comprehensive study of glycolysis is essential for a better understanding of the pathogenesis and therapeutic targets of both IBD and CRC. This paper reviews the role of glycolysis in diseases, particularly IBD and CRC, via its effects on the intestinal microbiota, immunity, barrier integrity, signaling pathways, transcription factors and some therapeutic strategies targeting glycolytic enzymes.
Development and implementation of a workshop for young adults with diabetes entering college and the workforce
Authors: West Margaret , Sidhaye Aniket , Thivierge Meredith , Wolf Risa M.
Published: October 2023

The process of transitioning from pediatric to adult diabetes care for adolescents and young adults is challenging. This transition period may include many life changes, and can be fraught with worsening glycemic control leading to increased risk for diabetes-related hospitalizations and complications. Research has demonstrated that increased support during this period can help maintain engagement in diabetes care. Transition guidelines highlight the importance of preparation and readiness for transition. In this article, we discuss the development, implementation and content of a workshop for patients and parents/caregivers preparing for the transition to college, the workforce and adult diabetes care.
Analysis of influencing factors of industrial green and low-carbon transformation under the background of “double carbon”: evidence from Sichuan province, China
Authors: Liu Bo , Chang Haodong , Li Yan , Zhao Yipeng
Published: October 2023

Introduction: Industrial green and low-carbon transformation is the key to improve economic development and necessary process to achieve the goal of the carbon peaking and carbon neutrality. Few studies have been done on the decomposition of carbon emission factors in industries and sub-industries and the impact of green and low-carbon transformation about carbon emission in each industry quantitatively. However, the study of industries and sub-industries can comprehensively analyze the development path of green and low-carbon transformation from a more detailed perspective, and provide scientific reasons for the optimization of industrial structure and energy structure.

Methods: The extended Kaya identity for industrial carbon emission is constructed to obtain four factors influencing industrial carbon emission: economic output effect, industrial structure effect, energy intensity effect, carbon consumption intensity in this paper. Then, the LMDI decomposition method is combined with the above identity to innovatively obtain the contribution value of carbon emissions from the perspective of overall, industrial sector and tertiary industry. Then, based on the results of factor decomposition, a multi-index scenario prediction model is constructed. On this basis, the extreme learning machine model optimized by particle swarm optimization (PSO-ELM) was used to predict the influence of the changes in the driving factors on the reduction of industrial carbon emissions. By setting the baseline and industrial green and low-carbon transformation scenarios, it is predicted that industrial carbon emission in Sichuan Province.

Results and discussion: (1) Economic output effect always promotes the growth of industrial carbon emissions, and with the adjustment of industrial structure and energy structure, the other three factors begin to restrain the growth of carbon emissions. (2) Scenario prediction shows that without considering the economic costs of transformation, improving carbon emission reduction efficiency can be obtained through accelerating the rate of change of industrial structure of the secondary and tertiary industries, increasing the proportion of energy intensity reduction, and strengthening the proportion of non-fossil energy use.
Global systematic map of research on bats in agricultural systems
Authors: Xavier Bruna Silva , Rainho Ana , Santos Ana M. C. , Vieira Marcus Vinícius , Carvalho William Douglas
Published: October 2023

Introduction

The conversion of natural habitats to agricultural systems is one of the main global threats to bats. Here, we aimed to develop a systematic mapping to identify publication trends and research gaps in studying bats and agricultural systems.

Methods

We reviewed 309 studies published between 1990 and 2021 that sampled bats in agricultural systems or evaluated the effect of these systems on these animals.

Results

We found that most studies were conducted in the Palearctic and Neotropical regions (55.3%) and forest biomes (66.0%). Grassland-cropland systems (50.2%) and forest plantations that do not require cutting during the extraction of their products (47.9%) were more studied than forest plantations that require cutting (19.7%). Additionally, acoustic recordings (41.1%) and mist nets (34.3%) were the primary sampling methods used, with few studies combining these methods (7.1%). Also, most studies were conducted on a local scale (77.7%). The number of landscape-scale studies was smaller (34.3%) and concentrated in the Palearctic region (39.6%). Most studies assessed how agricultural systems affect biodiversity (62.1%). However, the phylogenetic and functional dimensions and b-diversity were little explored, with 2.5% and 23.3% of the biodiversity studies, respectively. Of the proposed mitigation measures, the most cited was including natural/semi-natural/potential bat habitats in cultivated landscapes (59.5%).

Discussion

In summary, our findings highlight the need for attention to the Afrotropic and Indo-Malaysia regions; predominantly non-forested biomes; plantations that require cutting during the extraction of their products; combined use of different sampling methods, as well as other methods as telemetry; use of multiple biodiversity descriptors and others biological descriptors, such as ecological services; landscape-scale studies and the role of conservation policies in promoting their conservation and raising awareness of their importance among producers and local communities. Filling these knowledge gaps is necessary to understand the factors influencing bat survival in cultivated landscapes. This is the only way to develop management and conservation strategies in these landscapes.
The causality between obstructive sleep apnea and ventricular structure and function: a bidirectional Mendelian randomization study
Authors: Sun Wanli , Yang Fan , Yang Yiyuan , Su Xin , Xing Yanwei
Published: October 2023

Background: Multiple observational studies have discovered a substantial link between obstructive sleep apnea (OSA) and ventricular dysfunction. However, conventional observational studies are vulnerable to causal reversal and confounding, making it challenging to infer the causes of effects and their direction.

Methods: With the help of a bidirectional, two-sample Mendelian randomization (MR) study, we assessed the potential causality between OSA and left and right ventricular (LV, RV) structure and function. We conducted our analysis utilizing summary data from genome-wide association studies of OSA (16,761 cases and 201,194 controls) in the FinnGen Study, as well as LV (36,041 participants) and RV (29,506 participants) in the UK Biobank cardiovascular magnetic resonance research. The inverse variance weighted (IVW) was selected as the main strategy, with the MR-Egger and weighted median methods serving as supplements. Other methods were employed as sensitivity analysis tools to look at heterogeneity and pleiotropy, including MR-Egger intercept, Cochran Q statistic, MR-PRESSO, and leave-one-out analysis.

Results: In the primary IVW analysis, genetically predicted OSA was strongly causative on LV end-diastolic volume (β = 0.114, 95% CI = 0.034–0.194, p = 0.006) and LV stroke volume (β = 0.111, 95% CI = 0.031–0.191, p = 0.007), and genetically predicted LV ejection fraction was linked to an increased risk of OSA (OR = 1.161, 95% CI = 1.029–1.309, p = 0.015). However, there was no connection found between OSA and any RV parameters.

Conclusion: Our genetic analysis raises a potential causative link between OSA and ventricular structure and function, which may improve the knowledge of OSA as a risk factor for cardiovascular disease by demonstrating a direct impact on cardiac structure and function.
Monitoring oomycetes in water: combinations of methodologies used to answer key monitoring questions
Authors: Pettitt Tim R.
Published: October 2023

Monitoring oomycete populations and communities in bodies of water is vital in developing our understanding of this important group of fungus-like protists that contains many serious pathogens of both crops and wild plants. The methodologies involved in monitoring oomycetes are often presented as a developmental hierarchy, progressing from ‘traditional’ culture-based techniques through immunological techniques and basic PCR to qPCR and metagenomics. Here, techniques are assessed according to the roles they can perform in relation to four stages of the monitoring process: capture, detection and identification, viability determination, and quantification. Possible synergies are then considered for the combined use of different techniques in addressing the various needs relating to different questions asked of monitoring, with an emphasis on the continuing value of cultural and immunodiagnostic procedures. Additionally, the exciting future presented by the ongoing development and improvement of metabarcoding and the use of high throughput sequencing techniques in the measurement and monitoring of oomycete inoculum to determine and mitigate plant disease risks is addressed.