bluuebunny/crossref_metadata_2025 huggingface dataset:
A study of relationship between various platelet indices and outcome of dengue fever in pediatric patients
Authors: Mangshetty Roopa , A. B. Apurva , Harwal Shweta
Published: July 2023

Background: The study analyzed clinical characteristics and platelet indices in 200 children (1 month to 15 years) diagnosed with dengue fever, admitted to affiliated hospitals. It aimed to explore the relationship between platelet indices and disease severity in pediatric patients of teaching hospitals affiliated with MRMC College with a confirmed diagnosis of dengue fever.
Methods: In this study, the majority of patients were aged (10-15) years, with a small percentage (3.5%) being infants. Females accounted for 50% of the cases. Fever was the most common symptom, followed by headache, abdominal pain, and myalgia. Rash occurred in (14.5%) of cases. Among 200 cases, 80 exhibited warning signs, with varying positivity for NS1 and IgM. All patients required fluid therapy, and (77.5%) needed ICU care. Platelet count and Plateletcrit decreased initially but improved later, while PDW, MPV, and PLCR increased and then decreased. NS1-positive cases had lower platelet count and Plateletcrit but higher PLCR and MPV compared to IgM-positive cases.
Results: The study found that lower platelet count and Plateletcrit, as well as higher mean platelet volume, were associated with more severe disease outcomes, including longer hospital stays, increased intensive care unit care, and higher fluid therapy requirements. However, there was no significant correlation between other platelet indices (PLCR and PDW) and disease severity indicators.
Conclusions: In conclusion, this study provided valuable insights into the clinical features and platelet indices of patients with dengue fever. Understanding the relationship between these indices and disease severity can help in predicting the progression of the illness and improving patient management strategies.
Neonatal morbidity and mortality patterns in NICU at Al-Ameen Medical College and Hospital, Bijapur
Authors: Malagi Naushad Ali N. , Kumar Vallam Vinod , Gangawati Sujay P. , Thobbi A. N.
Published: July 2023

Background: Despite improvements in perinatal care, there is still a high rate of neonatal morbidity and mortality in developing nations like India. Neonatal period is defined as from birth upto first 28 days of life.
Methods: An observational prospective study was done with sample size of 600 babies admitted in NICU at AMCH, Bijapur during the period from January 2021 to August 2022. During the 18 months period of study, data was collected based on babies admitted with respect to gestational age, weight and day of life.
Results: The data analysis for morbidity showed that respiratory distress syndrome 24.6%, birth asphyxia with HIE 18.7%, jaundice 17.5%, sepsis 12.3%, meconium aspiration syndrome 4.7%, major congenital anomaly 3.4%, respiratory distress (other causes) 1.8%, others 17.3%. The disease wise mortality among neonates admitted to nicu was studied and were found that respiratory distress syndrome 35.5%, birth asphyxia with HIE 25.4%, sepsis 23.3%, major congenital malformations 6.1%, meconium aspiration syndrome 5.5%, others 4.1%.
Conclusions: The most common causes of admission were respiratory distress syndrome, birth asphyxia, jaundice, sepsis, meconium aspiration syndrome and major congenital anomalies. The most common causes of mortality were respiratory distress syndrome, birth asphyxia, sepsis and major congenital malformations.
Adequacy of traditional curette versus powered shaver for adenoid clearance: a comparative study
Authors: Kumaraswamy Nagarathna Hosalli , Warhapande Shruti S. , H. M. Saritha
Published: July 2023

Background: Adenoid growth is a prevalent aetiology of blockage of nasal passage in paediatric patients, and multiple techniques exist for their surgical removal. The objective of this investigation was to study the efficacy of the conventional curette versus the endoscopic guided powered shaver in the context of adenoid clearance.
Methods: In this study, a comparative analysis was performed on a sample of 119 patients, consisting of two distinct groups. Group I-60 patients who underwent conventional adenoidectomy, while group II-59 patients who underwent endoscopic microdebrider-assisted adenoidectomy. The methods employed in this study were in accordance with established medical practises. The research evaluated outcome measures including surgical duration, haemorrhage, and perioperative and postoperative adverse events.
Results: Group I, 17 (28.3%) received adenoidectomy as a standalone procedure, group II, 22 (37.3%) received adenoidectomy as a standalone procedure. An adenotonsillectomy was executed on 21 patients, accounting for 35% of group I, and 10 patients, accounting for 16.9% of group II. The study found that group I exhibited significantly reduced operation time and blood loss compared to group II (20.88±4.41 vs. 29.00±4.15 minutes and 13.47±3.02 vs. 18.64±3.16 millilitres, respectively). Intraoperative complications were observed in 10% of patients in group I and 5.1% of patients in group II. The group II participants exhibited a more rapid onset of symptomatic relief compared to those in group I. There was no evidence of recurrence in the cohort of patients who underwent endoscopic microdebrider-assisted adenoidectomy.
Conclusions: Endoscopic microdebrider-assisted adenoidectomy is a superior and dependable technique compared to curettage, exhibiting improved clearance rates and patient contentment.
Prevalence of meconium-stained amniotic fluid in SARS COVID-19 positive pregnant mothers and its manifestations in newborns
Authors: Reddy Shilpa , H. S. Surabhi , E. Adarsh
Published: July 2023

Background: This study is being conducted to find out whether coronavirus disease 2019 (COVID-19) is associated with an increased incidence of MSAF in COVID-positive pregnant women. Finding implications for operative delivery and perinatal outcome. The evidence will help in managing COVID-positive women in pregnancy.
Methods: This prospective observational study was conducted from July 1, 2020 to October 20, 2020 at Rajarajeswari Medical College and Hospital, Bangalore. A total 38 newborns born to SARS-COVID-19 infected mothers were included. Data collected from pregnant women, patient records, birth registries, operating room/delivery room records and NICU registries.
Results: The clinical characteristics of 38 mothers and their newborns were analyzed. The mode of delivery was normal vaginal delivery (NVD) in most (N=21) cases. All newborns tested negative for SARS-CoV-2. 18 babies required only routine newborn care, and 20 babies required neonatal intensive care unit (NICU) admission at birth for management of meconium-stained amniotic fluid (MSAF)(11pregnancies), prematurity (3 cases), dyspnea (6 cases), stage 2/3 hypoxic ischemic encephalopathy (HIE) (2 cases), and Jaundice (9 cases). 18 of 38 stable babies held mother's side and breastfeeding started, with no signs and symptoms attributed to SARS-CoV-2.
Conclusions: In our study, the prevalence of MSAF is higher (28%) in COVID-19 Positive mothers, resulting in low APGAR scores and poor perinatal outcomes. Vigilant intrapartum care is recommended to reduce the risk of poor neonatal outcomes. No newborns developed signs and symptoms of SARS-CoV-2 infection during rooming-in, breastfeeding and during admissions at neonatal intensive care unit (NICU).
Study of incidence, microbiological profile of nosocomial infections in pediatric intensive care unit of tertiary care center
Authors: Malagi Naushad Ali N. , Sushma Uppalapati , Thangavelu S. , Shanthi S. , Ramchandran P. , Indumathi  , Ravichandran C. , Gangawati Sujay P. , Lahari Darla Sri Sai
Published: July 2023

Background: Prevalence of nosocomial infections in pediatric intensive care unit (PICU) ranges between from 6-26%. Increased use of broad-spectrum antibiotics, urinary and central venous catheterization and endotracheal intubation put patients at an increased risk of affecting with nosocomial infections in pediatric patients.
Methods: A hospital based prospective study was carried out on 725 patients aged between 1 month and 12 years admitted in PICU of Al-Ameen medical college hospital, Bijapur, Karnataka, India and institute of child health and hospital for children, Madras medical college, Chennai, Tamil Nadu, India from 15-09-2020 to 15-08-2022. All patients who were admitted with fever or developed fever in first 48 hours of life were excluded from the study. The data obtained in the course of study was analyzed by appropriate statistical methods.
Results: Out of 725 pediatric admissions, the incidence of nosocomial infection in the present was found to be 108 (14.8%). Concerning the type of infection, the commonest reported types were central-line associated bloodstream infection (CABI) 59 (54.6%) and ventilator-associated infection (VAI) 52 (48.1%), followed by bloodstream infection 45 (41.6%), catheter associated urinary tract infection (CA-UTI) 38 (35.1%) and urinary tract infection (UTI) 30 (27.7%) respectively.
Conclusions: The incidence of nosocomial infection was 14.8%. The central line associated blood stream infection was the predominant cause of nosocomial infection. This information can help decision makers establish preventive strategies and implement effective and reliable plans.
Impact of fetal malnutrition in mid-childhood and early-adolescent age
Authors: Sawant Sangeeta P. , Amin Alpa S. , Kumar Santosh , Sule-Kalane Shilpa
Published: July 2023

Background: Fetal malnutrition is accompanied by short-term and long-term morbidities in children. Objective was to assess impact of FM on physical growth, blood pressure and neurodevelopment in mid childhood and early adolescent age.
Methods: An observational, retrospective, study was undertaken in an urban multispecialty hospital of Mumbai, India on a closed cohort of 54 children born in year 2006-2007. They had been assessed for their nutritional status at birth by clinical assessment of Nutrition score (CAN score) described by Metcoff. Twenty – five children had evidence of FM (FM – group) and 29 had normal nutritional status at birth (Non – FM group). They were in their mid-childhood and early-adolescent age at time of present study. Anthropometry and Blood pressure measurement of children were taken. Scholastic performance and any neurodevelopmental problem were enquired and medical records were checked.
Results: In mid-childhood and early-adolescent age, absolute risk of overweight /obesity (36% vs. 20.68%), Central obesity (8.0% vs. 3.44%), prehypertension/hypertension (8.0% vs 3.44%) and neurodevelopmental problems (24% vs. 3.44%) in FM- group children was more compared to Non-FM- group. Also, FM- group children had 1.74, 2.32, 2.32 and 6.96 times more risk of overweight/obesity, central obesity, prehypertension/hypertension and neurodevelopmental problems.
Conclusions: Fetal malnutrition has significant impact on physical growth, blood pressure measurement and neurodevelopment outcome in mid childhood and early adolescent age.
Purpura fulminans-a rare complication post COVID-19 infection in children
Authors: Pereira Rochelle A. , Mundkur Suneel C. , Neminathan Akshaya , Moras Karen J. , George Divya Mary
Published: July 2023

Coronavirus disease 2019 (COVID-19) was officially declared as a pandemic in March 2020. COVID-19 infection and the post infectious sequalae has been widely researched since then. Post infectious inflammatory sequalae and its associated complications like toxic shock syndrome, Kawasaki like disease, macrophage activation syndrome, rather than the infection per se was found to be more of a concern in children, leading to more morbidity and mortality. Purpura fulminans was not a presentation reported post COVID-19 infection. Herein, we aim to describe a post COVID-19 infection patient who presented with purpura fulminans as a rare complication.
Multiple congenital esophageal strictures masquerading as gastroesophageal reflux disease in an infant: a case report
Authors: Sharma Yash P. , Sharma Shruti , Surya Mukesh , Kapila Sumala
Published: July 2023

Congenital esophageal stenosis (CES) is a rare congenital disorder, generally presenting as vague complaints of dysphagia, vomiting and frequent respiratory complaints with symptoms usually appearing with introduction of complimentary feeding. We present the case of an eight-month-old male infant, presenting with regurgitation of feeds, recurrent episodes of cough and poor weight gain. He was diagnosed as a case of isolated multiple membranous esophageal strictures and underwent serial endoscopic esophageal dilatations which subsequently allowed him to swallow solid food and achieve good weight gain.
Multistage standardization of Beraphone and OAE on neonates
Authors: Chatterjee Indranil , Ata Seunti , Shatapathy Pragati , Kumar Suman , Samaddar Pamela , Makkar Sujoy , Dutta Palash , Samanta Sandip , Mukherjee Suchandra , Barman Debashish , Arefin M. Sahidul
Published: July 2023

Background: Universal newborn hearing screening is a strategy to identify children with all kinds and degrees of hearing impairment, to lower the age at the time of diagnosis for early hearing amplification, to maximize their linguistic competence and literacy development.
Methods: This study was conducted over the period of 9 months on 200 newborns selected from well-baby nursery and 30 infants from the SNCU unit of the hospitals to obtain field evidence of newborn hearing screening in Indian context by using TEOAE and AABR tests of MAICO easy screen beraphone instrument as well as to standardize the instrument. The process was carried out in different phases at different state government hospitals and the data was collected from the different departments of the hospitals. The obtained data were transferred to an excel spreadsheet. Then the nonparametric Mann-Whitney U test and Wilcoxon Signed rank test were done by using SPSS software version 21. The detailed analysis was done for the age, sex and ear specific values.
Results: The results showed a significant difference not only between well-baby and SNCU but also between left and right ear. It is represented both in the tabular and graphical way to explain the findings in detail.
Conclusions: It can be stated that the MAICO easy screen beraphone instrument can be used for clinical and further research purposes related to newborn hearing screening suitable for infants up to 3 months of age because of its high sensitivity and specificity value.
The association between blood sugar control and hearing impairment in individuals with type 2 diabetes mellitus: a prospective study using otoacoustic emissions as a biomarker
Authors: Walia Inderpal Singh , Kumar Sanjay , Singh Shailendra , Biradar Kashiroygoud , Kumar Sudheer
Published: July 2023

Background: The existing association between hearing impairment and diabetes mellitus (DM) prompted us to investigate the relationship between glycaemic control, as measured by HbA1c levels, and hearing impairment in individuals with type 2 diabetes mellitus (T2DM).
Methods: In this study, we assessed the auditory function of a sample of 100 individuals diagnosed with T2DM, who were aged 30 years or older and had a disease duration of at least 5 years. The evaluation was conducted using distortion product otoacoustic emissions and transient evoked otoacoustic emissions. The criteria for poor glycaemic control were established as HbA1c levels equal to or exceeding 7.5%.
Results: Individuals with a haemoglobin A1c (HbA1c) level of 7.5% or higher exhibited a nearly threefold increased likelihood of developing hearing impairment in comparison to those with lower HbA1c levels. The gender-based observation revealed a stronger association in females, although the observed correlation did not reach statistical significance.
Conclusions: The findings of our study establish a significant association between inadequate management of blood glucose levels and the occurrence of hearing impairment among individuals with T2DM. These results underscore the importance of achieving optimal glycaemic control as a means of preventing hearing impairment in this patient population. Further investigation is required to substantiate these findings through a comprehensive and longitudinal research approach.
Study of etiopathogenesis and management of epistaxis in tertiary care centre
Authors: M. Muniraju , P. R. Julie
Published: July 2023

Background: Epistaxis is one of the most commonly addressed complaints in patients visiting outpatient department of ENT. This study aimed to determine common etiologies and management of epistaxis in a Tertiary care centre.
Methods: This prospective descriptive study was conducted with 60 patients selected by consecutive sampling presented to our hospital with epistaxis between the years 2021-2022.
Results: Incidence of epistaxis was more in males (58.33%) with male to female ratio of 1.4:1. Most common age group was between 10-49 years (68.33%). The commonest etiology was idiopathic (30%). When the cause was present, trauma was the most common reason mainly in young adults (13.33%) followed by hypertension (11.67%). The most common site of epistaxis was noted in the anterior nasal cavity (45%) where Little’s area (20%) was the most common location. Most cases were managed by conservative non-surgical treatments alone (55%) like anterior and, or posterior nasal packing, chemical/ electro-cauterization, foreign body removal, and blood components transfusion. Almost an equal number of patients underwent Surgical management in our hospital (45%) as it is a tertiary care centre.
Conclusions: Epistaxis is an ENT emergency seen in all age groups, more common in adolescents and young adults, males are affected more than females. The cause of epistaxis was not known in most cases, i.e., Idiopathic. Most of the cases can be managed by non-surgical treatment. It is necessary for the treating doctor to accurately diagnose the etiology of the case, and bleeding site and treat accordingly.
Limberg’s flap technique: a defect repair method for ear lobe reconstruction in recurrent earlobe keloids: a case report
Authors: Tantry Deepalakshmi , Tantry Gururaj , R. S. Chitra , M. Sapna
Published: July 2023

The article acts to focus and aid in the localization of sound. Its shape is aesthetically important as it shows considerable inter-individual variability which reflects its multicomponent and is quite challenging for the surgeons during the planning of reconstruction as it is complex and equally important. It’s complex undulating structure and topography includes fibro elastic cartilage, perichondrium and the skin. The ear lobule is an important reference point for symmetry of the face and its loss causes an obvious aesthetic abnormality. Excessive healing can be as significant as delayed or non-healing. Recurrent earlobe keloids are among the most challenging conditions and may have significant psycho-social impact for the patient. Their aesthetic considerations are serious and despite a variety of treatment options, they often proved to be recurrent. It is likely that more operative interventions are required for excessive healing. Type II A defects are characterized by loss of the ear lobule without presence of a nubbin of tissue attached to the cheek. The goal of surgery should be an aesthetically pleasing reconstruction that maintains symmetry with the opposite ear lobule. The Limberg‑flap technique using a doubled‑over skin flap allows a one stage reconstruction of the ear lobule. The aesthetic results are generally well acceptable and hence here we present a case where we combine this technique with the excision for better results of long-term refractory cases.
A case of right parathyroid adenoma and its management
Authors: M. K. Vybhavi , V. Prashanth , Muddaiah Dechu , V. Srinivas
Published: July 2023

A 33 year old female patient presented with history of body and joint pain with easy fatiguability unable to perform her routine daily activities since 2 months. She also gave history of recurrent urinary tract infections, pain abdomen, loss of appetite and loss of weight. Examination of neck showed no palpable mass. Laboratory data revealed elevated serum calcium levels and parathyroid hormone levels. Contrast enhanced computed tomography of neck showed well-defined soft tissue density lesion measuring 2.6×1.9×1.6 cm in the postero inferior aspect of right lobe of thyroid suggestive of right parathyroid adenoma. Parathyroid imaging (SPECT) 99mTc-MIBI showed focal increased tracer uptake in relation to inferior aspect of right lobe of thyroid gland. NCCT KUB showed bilateral non obstructive renal calculi with medullary nephrocalcinosis. Patient underwent surgical resection under general anesthesia and histopathology confirmed parathyroid adenoma. Following surgery, parathyroid hormone and calcium levels gradually returned to normal levels. Parathyroid adenoma shows excellent prognosis with complete surgical resection.
Thuja as an adjuvant medical management of juvenile recurrent laryngeal papillomatosis: our experience
Authors: Sharma Navneet , Mishra Ankita
Published: July 2023

A subgroup of recurrent respiratory papillomatosis, which is a larger clinical entity, is laryngeal papillomatosis. The vocal folds produce recurrent papillomata, which is a hallmark of the condition. The two most prevalent strains of human papillomavirus have been linked to the development of laryngeal papillomas, types 6 and 11. Distinctive presence of warty lesion on endoscopy is basis for clinical diagnosis. Surgery is the foremost treatment possibility, combined with adjuvant therapy such antiviral medications and immunomodulators. Thuja occidentalis, a tree whose leaves and leaf oil have anti-oxidant,antiviral,anti tumoral,anti inflammatory, antibacterial and antifungal properties. It has been extensively utilized to treat warts and condylomatous skin lesions. In this article, we go through the results of using Thuja as an adjuvant therapy for laryngeal papillomatosis in a 16-year-old female.
Construcción del «Atlas fotográfico de alimentos y bebidas estandarizadas», para apoyo en la aplicación virtual de la encuesta de «24 horas recordatorio método multipasos» y «Rastreador NOVA 27 categorías de UPF»
Authors: Freire Wilma B. , Chávez Andrea Michel , Jiménez Elisa , Blemont Philippe
Published: July 2023

Objetivo del manual para uso del «Atlas fotográfico de alimentos y bebidas estandarizadas»

Este manual fue elaborado para apoyar a la aplicación virtual de la encuesta de «24 horas recordatorio método multipasos» y del «Rastreador NOVA de 27 categorías de UPF».

Fuentes de información para la construcción del atlas

Para la construcción del Atlas fotográfico de alimentos y bebidas estandarizadas se utilizaron cuatro fuentes de información:

el «Catálogo fotográfico como herramienta para la estimación de la ingesta alimentaria en niños y adultos» elaborado por Chumbi y Vásquez, (1)

el «Atlas fotográfico» del programa Aliméntate Ecuador del Ministerio de Inclusión Económica y Social, (2)fotos de productos ultra procesados sin identificación de origen y

la «Encuesta Nacional de Salud y Nutrición de la Población Ecuatoriana de Cero a 59 Años. ENSANUT 2012», capítulo encuesta de consumo. (3)

El «Catálogo fotográfico» publicado por Chumbi y Vásquez (1) y el «Atlas Fotográfico» publicado por el Aliméntate Ecuador (2) se diseñaron para recolectar información cuantificada del consumo de alimentos con entrevistas cara a cara. En ambos casos, el registro de alimentos se hizo por porciones asignando códigos que diferencian a cada alimento y porción de este, en cuanto al volumen y cantidad en gramos y/o mililitros.

Debido a que el «Catálogo fotográfico» de Chumbi y Vásquez (1) y el Atlas de Aliméntate Ecuador (2) no registran la categoría de productos ultra procesados que son parte de la dieta que consumo de alimentos de la población. Se decidió agregar al Atlas de fotos de alimentos y bebidas ultra procesados, bebidas y alimentos sin identificación de origen. Una vez seleccionadas las fotos de estas tres fuentes, se las agrupó en cinco categorías, 65 subcategoría y 118 porciones.
«Rastreador NOVA»: Validación estadística del «Rastreador NOVA» como instrumento que captura el consumo de los ultraprocesados
Authors: Belmont Phillipe , Freire Wilma B.
Published: July 2023

En Ecuador, el sobrepeso y la obesidad (sp/ob) alcanzan altos niveles de prevalencia alarmantes en la población adulta y adolescente. Entre los impulsores identificados que aumentan la prevalencia de sp/ob, están los hábitos sedentarios, la pérdida de diversidad alimentaria y el consumo de alimentos ultraprocesados (UPF) que son parte de un fenómeno identificado como transición nutricional. El desarrollo del sector agroindustrial, junto con el estilo de vida urbano contribuyen al cambio en los patrones de alimentación, aumentando los riesgos de enfermedades crónicas no transmisibles. Esta transición ocurre cuando las dietas “tradicionales” son reemplazadas por pocos alimentos básicos y mayor consumo de UPF. Por lo tanto, se hace necesario contar con un instrumento simple, y de bajo costo que permita hacer un seguimiento permanente y periódico de la ingesta calórica UPF, para disponer de datos oportunos que alimenten las decisiones de políticas y programas que protejan las practicas alimentarias saludables y sustenten la necesidad de adoptar programas de producción y oferta de alimentos saludables.
Изучение влияния музыки на степень концентрации внимания
Authors: Анферова М.Д , Веер Е.Д , Гагарина Е.М
Published: July 2023

В данной статье рассматривается проблема поддержания высокой концентрации внимания. Исследуется идея о том, что прослушивание музыки во время выполнения определѐнных задач приводит к увеличению уровня концентрации внимания посредством создания неинвазивного шума, нагружающего работой непроизвольную систему внимания для исключения возможности еѐ отвлечения на раздражитель, и приятных ощущений, придающих позитивную эмоциональную окраску рабочему процессу.
Цитомегаловирусная инфекция у пациентов с воспалительными заболеваниями кишечника
Authors: Егизгельдинова Ж.Е , Ивачѐва С.Я , Кадырова А.Ж , Чункенеева А.С , Ларюшина Е.М , Кабдулина Н.А , Бейсембаева Г.А
Published: July 2023

Цель: определение распространенности цитомегаловирусного колита (ЦМВ - колита) и особенности клинико-эндоскопической, лабораторной картины течения заболевания у пациентов с воспалительными заболеваниями кишечника (ВЗК). Материалы и методы: Работа проведена на базе гастроэнтерологического отделения Областной клинической больницы г. Караганды. Определение распространенности цитомегаловирусной инфекции (ЦМВИ) у пациентов с ВЗК оценивалась путем ретроспективного анализа 177 историй болезни за период 2021-2023 года. Пациенты были осмотрены колопроктологом с проведением ректороманоскопии и взятием биоптата со слизистой прямой кишки с последующем определением ДНК ЦМВ методом полимеразной цепной реакции (ПЦР). Результаты качественного анализа получены методом ПЦР в режиме real — time с помощью системы Rotor - Gene Q. Изучалась активность заболевания путем анализа выраженности клинической картины по индексам Мейо при язвенном колите и Харвей - Брэндшоу при болезни Крона, маркеров системного воспалительного ответа, а именно уровень лейкоцитов, тромбоцитозов и острофазовых показателей (скорости оседания эритроцитов, С - реактивного белка), фекального кальпротектина, эндоскопической картины. Статистическая обработка результатов исследования проводилась с использованием программы STATISTICA. Результаты: Выявлено 24 случая с ЦМВ-колитом. Распростаненность ЦМВИ у пациентов с ВЗК составила 13,6% , из них в половом соотноошении - 14 мужчин (58,3%) и 10 женщин (41,7%). В разрезе заболеваний: у 18 человек (75 %) с язвенным колитом и 6 (25%) с болезнью Крона. В клинической картине значительно преобладала диарея с кровью, эндоскопически имело место тотальное поражение толстого кишечника, как у пациентов с язвенным колитом, так и с болезнью Крона. Присоединение цитомегаловирусной инфекции сопровождалось повышением уровня маркеров системного воспалительного ответа, в частности лейкоцитозом, ускорением СОЭ и повышением СРБ, что свидетельствовало об усилении воспалительного ответа. Обращало внимание значительное повышение уровня фекального кальпротектина (Мe (Q25-75) = 2140 (298,25;2754)) у большинства пациентов. Заключение: Тотальное поражение толстого кишечника, значительное повышение показателя кишечного воспаления (фекальный кальпротектин), а также маркеров системного воспалительного ответа с неэффективностью стандартной базисной терапии, должно настораживать в плане присоединения ЦМВ-инфекции, а также других оппортунистических инфекций. Проведение исследования биоптата слизистой прямой кишки методом ПЦР на ЦМВИ необходимо включать в основной перечень обследований при ВЗК всем пациентам, имеющим отсутствие ответа на проводимую терапию, а также при дебюте или любом рецидиве заболевания.
Гигиена рук в медицинских организациях: эффективная мера профилактики ИСМП
Authors: Сметанин В.Н.
Published: July 2023

Инфекции, связанные с оказанием медицинской помощи (ИСМП), являются актуальной проблемой современного российского здравоохранения. Основными причинами ИСМП являются недостаточно эффективные методы инфекционного контроля в медицинских организациях и чрезмерное использование противомикробных препаратов. Целью данного исследования является обоснование гигиены рук в медицинских организациях в качестве наиболее эффективной меры профилактики ИСМП в рамках реализации Национальной Концепции профилактики инфекций, связанных с оказанием медицинской помощи (утв. Главным государственным санитарным врачом РФ 6 ноября 2011 г.). Для достижения поставленной цели использовались такие методы как контент-анализ, литературный обзор, ранжирование, гипотетико-дедуктивного метода, обобщение, формализация. В качестве материалов использовались статьи, опубликованные в международных библиографических и реферативных базах данных (Scopus, PubMed); официальные документы Российской Федерации, а также международные документы (законодательные акты, программы, конвенции и т.д.), посвященные вопросам инфекций, связанных с оказанием медицинской помощи. Выполненный систематический литературный анализ говорит о том, что одной из основных мер профилактики ИСМП является гигиена рук. При этом максимального результата в ходе профилактики ИСМП можно добиться посредством реализации мультимодального подхода. На основании имеющихся научных исследований определены 5 основных моментов, когда медицинскими работниками обязательно проводится гигиена рук.
Повышение внутренней мотивации студентов
Authors: Османов Г.М. , Севодин С.В.
Published: July 2023

В данной статье рассматривается проблема низкой мотивации студентов для занятия спортом и предлагаются методы ее повышения. Авторы основываются на теории самоопределения и предлагают использовать такие методы, как установление целей, поддержка социальной среды, участие в соревнованиях и другие.
Силовая подготовка как важная составляющая физического воспитания студентов
Authors: Ходова А.Р. , Карева Ю.Ю.
Published: July 2023

В статье рассматривается вопрос влияния силовых тренировок на занятиях по физической культуре на показатели физической подготовленности студентов. Представлены результаты исследования, которые показали значительное повышение силовых показателей в результате включения силовой подготовки в занятия по физической культуре. Приведены данные анкетирования студентов относительно использования силовых упражнений в процессе физической подготовки
К вопросу о способах восстановления студентов после интенсивной физической нагрузки
Authors: Чистякова И.А. , Митина С.М. , Кудинов С.В. , Рожнова А.А. , Рожнов А.А.
Published: July 2023

В данной статье поднимается актуальная проблема восстановления студентов, активно занимающихся спортом, после интенсивной физической нагрузки. Отмечается что наряду с естественными способами восстановления, существуют и искусственные основанные благодаря современным достижениям фармакологии. Даны рекомендации для тренеров студенческих спортивных команд по использованию средств восстановления студентов.
Reconstrucción del Estado de posguerra: Irak después de ISIS como estudio de caso
Authors: Rached Kardo , Jamil Shakar
Published: July 2023

La turbulencia política, el vacío de poder y los desafíos de seguridad que surgieron en Irak posterior a ISIS modificaron la estructura de poder del estado. El aparato de seguridad y las instituciones militares iraquíes por poco colapsan en 2014 y no pudieron resistir los desafíos que tuvieron que enfrentar desde ISIS. De manera simultánea, el gran clérigo chiita Sistani emitió una fatwa, llamó a los chiitas a las armas y luchó por su supervivencia. En esta situación desordenada, un número cada vez mayor de grupos armados respaldados por Irán han comenzado a manejar los desafíos de seguridad, la mayoría de los cuales operan de forma independiente por fuera de las agencias de seguridad nacional de Irak. El grupo más importante fue el de las Fuerzas de Movilización Popular (FMP), de la comunidad chiita iraquí. Las FMP se enredan gradualmente en los asuntos financieros y el sistema político de Irak y ejercen una tremenda influencia. Hay dos tipos de milicias relevantes en Irak: las milicias paramilitares Al-Atabat al-Muqadasa (MPAA) y las milicias leales (ML). En mayo de 2021, cuatro divisiones de MPAA decidieron integrarse al ejército iraquí, mientras que las ML cuentan con casi 70 divisiones diferentes y no se han integrado a las instituciones del gobierno. En este artículo, exploramos la posibilidad de implementar el modelo DDR para sociedades de posguerra como la iraquí y los obstáculos que enfrentaron. La integración de estos grupos armados se convirtió en una tarea complicada para el estado de Irak Post-ISIS. En primer lugar, examinamos la historia del proceso de construcción del Estado. Luego, desarrollamos un marco conceptual para el artículo. En tercer lugar, identificamos los factores que dan forma a los resultados de DDR, definimos el papel de las Fuerzas de Movilización Popular (FMP) y analizamos cómo sus actividades se convirtieron en un obstáculo para reconstruir el estado iraquí en la era posterior a ISIS.
Editorial
Authors: Franco Vásquez José Gabriel
Published: July 2023

El segundo numero del 2023 de Medicina UPB trae nueve articulos. De ellos, cuatro son investigaciones originales, dos son revisiones narrativas y tres son reportes de caso. Entre los originales hay un estudio de validacion de un instrumento diagnostico, un ensayo clinico y un estudio con aspectos cualitativos.
Effect of the heat-transfer agent flow nonstationarity in the matrix channel of a rotating heat exchanger on its thermal parameters with the laminar flow
Authors: Kostyukov A.V. , Kosach L.A. , Merzliki V.G.
Published: July 2023

The paper studies influence of the non-stationarity process of the laminar gas flow in the band flat matrix channel of the rotating heat exchanger on its thermal characteristics. Conjugate heat transfer was mathematically simulated with the airflow along the steel walls forming the channel under study. In view of peculiarities of the rotating heat exchanger operation and to obtain parameters of the conjugate heat transfer in the nominal mode, mathematical simulation was performed many times using the results previously obtained as the initial conditions for the following calculations. It was established that gas flow in the investigated matrix channel of the heat exchanger became cyclically repetitive after the sixty cycles. Distribution curves of Nusselt criterion local values along the channel length at all time steps of the gas flow process, as well as the Nusselt criterion values averaged over the channel length were obtained. It was shown that the length-averaged Nusselt criterion value was smoothly increasing with time. The time-averaged Nusselt criterion value was determined, and it was somewhat exceeding the values obtained in the stationary setting.
Computational, theoretical and experimental study of cavitation characteristics of the gate wellhead devices with the internal bypass
Authors: Muftakhov V.Z.
Published: July 2023

Hydraulic systems include control devices that create local resistance. Decreasing and increasing the working medium pressure and flow rate in the control devices cause cavitation, vibration, noise, material destruction, increase in the energy losses and decrease in the efficiency, which adverse effects could be reduced by using a bypass. One of the important tasks in designing the control devices is establishment of the cavitation characteristics. Introduction of an internal bypass in such devices makes it possible to reduce forces on the control elements displacement and the specific pressures in opening and closing, as well as to locate the cavitation bubbles collapse point in the flow behind the control gates. The paper presents results of a computational theoretical study using a modern complex of engineering analysis and experimental determination of the cavitation characteristics of the gate wellhead device with an internal bypass.
Machine learning and artificial intelligence in the prediction, diagnosis and treatment of thoracic aortic diseases (literature review). Part 1
Authors: Uspenskiy V. E. , Saprankov V. L. , Mazin V. I. , Filippov A. A. , Boyarskaya N. V. , Malashicheva A.  B. , Moiseeva O. M.
Published: July 2023

Despite their relatively low prevalence compared to cardiac valve lesions and coronary heart disease, thoracic aortic aneurysm and dissection are potentially fatal and represent serious public health problems. The indications for surgical treatment in most thoracic aortic diseases are predominantly based on the maximum aortic diameter in a particular area. Congenital connective tissue disorder, thoracic aortic anomalies (e.g., coarctation), family history of aneurysms, aortic dissections, and sudden deaths are considered as additional risk factors of aortic-related complications influencing the “stricter” indications and lowering the “threshold” aortic diameter. At the same time, a certain proportion of patients with aortic diseases develop aortic dissection and rupture in normal or near-normal thoracic aortic diameter in certain section. Many factors influence the development of aortic diseases and complications, and assessing the contribution to the aetiology and pathogenesis of each factor is difficult. Machine learning and mathematical modeling using artificial intelligence is an actively developing area of computer science, which also finds application in medicine, in particular in the study, diagnosis, and treatment of thoracic aortic aneurysms and dissections. This article discusses modern methods of data analysis, prediction of thoracic aortic aneurysms and dissections, treatment planning in thoracic aortic diseases, and prediction of complications using machine learning and artificial intelligence.
Genomic medicine in Russia: future perspectives
Authors: Samsonova A. A. , Kanapin A. A. , Chernyaeva E. N. , Abramov I. S. , Shipulin G. A.
Published: July 2023

Modern genome technologies and a widespread use of omics data have revolutionized healthcare and brought unprecedented opportunities to apply genetics to medicine to maximize patient benefit. Genomic medicine provides innovative approaches to rapid and reliable early disease diagnostics, patients stratification to assess and monitor the effectiveness of therapy and, finally, population-scale screening for predisposition to certain diseases. In view of this, many countries took steps to adopt of genomics in clinical practice, thus transforming national healthcare systems. Here we discuss main applications of genomic data in clinical practice, its contribution to personalised medicine and associated emerging challenges, as well as key considerations for the successful integration of genomic technologies into healthcare systems. Besides that, we showcase several national genomic medicine programmes, particularly the UK one, providing a detailed review of approaches to transformation of the national healthcare system as implemented by Genomics England initiative. Finally, we discuss possible avenues for the development of genomic medicine system in Russia.
CONSUMPTION OF MINE WATER BY WILD UNGULATES IN THE SOURCES OF THE USSURI RIVER, ON THE TERRITORY OF THE NATIONAL PARK «CALL OF THE TIGER»
Authors: Panichev Alexander M. , Baranovskaya Natalia V. , Aramilev Vladimir V. , Chekryzhov Igor Yu. , Vakh Еlena А. , Vetoshkina Alena V. , Lutsenko Tatyana N. , Strepetov Dmitry A.
Published: July 2023

Link for citation: Panichev A.M., Baranovskaya N.V., Aramilev V.V., Chekryzhov I.Yu., Vakh E.A., Vetoshkina  A.V., Lutsenko T.N., Strepetov D.A.  Consumption of mine water by wild ungulates in the sources of the Ussuri river, on the territory of the national park «Call of the tiger». Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no. 7, рр. 111-121. In Rus.
The relevance of the study is determined by the need to clarify the reason for the use of mineralized water by wild animals, which is typical for many areas of the world. The new knowledge is closely related to the geophagy problem, the solution of which opens a wide prospect of fundamental research in the fields of landscape biogeochemistry, ecology and medicine. Purpose: to study chemical composition of the mineralized mine water in the lake located on the territory of the out-of-operation tin-polymetallic ores concentrator dump in the upper Ussuri river which is being consumed actively by wild ungulates; to reveal number of animal visitors to the lake during an annual cycle; to reveal the reason of mine water consumption. Objects: ungulates visiting the lake with mine water; lake water and bottom sediments. Methods: estimation of visitation of the mine lake by animals by means of photographic traps; chemical composition determination: inductively coupled plasma mass spectrometry (ICP-MS) (Agilent 7700x spectrometer, Agilent Techn., USA); atomic emission spectrometry (spectrometer iCAP 7600 Duo); ion chromatography (LC-20 ion-liquid chromatograph, Shimadzu, Japan). Results. It was revealed that animals come to the lake uniformly throughout the year, except for the winter period, when the water is covered by a thick layer of ice. In high concentrations trace elements were found, including both elements with high toxicity (Cd and Pb) exceeding MAC for drinking water from 20 to 80 times and essential elements such as Fe, Mn, Cu, Zn, Co, Cr, Ni, Se, Li, which concentration either does not exceed MPC or exceeds it insignificantly. The concentration of REE, especially of the light subgroup, is also very high. The reason for mine water consumption by animals, most likely, is the high concentration of rare-earth elements of the light subgroup in it.
МЕХАНИЗМЫ НЕГАЦИИ В ОКОЛОСПОРТИВНОЙ ФАНАТСКОЙ СУБКУЛЬТУРЕ ПО ФИГУРНОМУ КАТАНИЮ
Authors: Карина Сергеевна Смердова
Published: July 2023

В статье рассматриваются особенности функционирования спортивной фанатской субкультуры,сформировавшейся под воздействием высокой конкуренции в фигурном катании. Актуальностьтемы связана с необходимостью изучения проблемы негативного влияния радикальных фанатов наспортивную действительность, обусловленного тем, что именно радикализированные субъектыфанатской субкультуры проявляют черты негативной идентичности. Цель исследования: изучениеи выявление специфики интернет-коммуникации спортивных фанатов. Для этого были рассмотрены различные приемы негации в сторону Других, а также причины, провоцирующие агрессивное поведение радикального фаната; дифференцированы понятия «фанат» и «радикальный фанат».Методы: включенного наблюдения и контент-анализа. При помощи данных методов получены результаты, позволяющие выделить следующие специфические установки поведенческой модели фаната, которому свойственна агрессивная реакция на Другого: фан-объект добивается результатоввопреки желаниям или ставкам тренера, любые достижения – исключительно личная заслугаспортсмена; профессиональная среда настроена против фан-объекта, эксперты или журналисты,критикующие фан-объект, являются либо коррумпированными, либо некомпетентными; определенное достижение спортсмена возводится в абсолют. Выводы: фанаты конструируют собственную «спортивную реальность», идеальную модель фан-объекта и образ врага на внерациональных, эмоциональных основаниях. Жестко и агрессивно отстаивая истинность своей позиции в пространстве профессиональной деятельности кумира, фанаты используют специальный понятийный аппарат, присваивают себе статус знатока, интерпретируют мнение экспертов сквозь призму собственного восприятия, отрицают их точку зрения, основываясь на убежденности в предвзятости специалиста.
Influence of Moisture Content on Germination and Physico-Mechanical Properties of Pulses
Authors: Gupta K. , Khura T.K. , Kushwaha H.L. , Parray R.A. , Sarkar S.K.
Published: July 2023

Background: Pulses are a kind of legume crops which can be utilised for both food and animal feed. Pulses are also termed a “poor man’s meat” because of high protein content. The physical properties of pulses are useful to design the processing equipment. The moisture content of agricultural materials greatly affects various physical properties. Nitty-gritty data on germination and physico-mechanical properties of pulses are provided in this paper at different moisture contents, which is extremely helpful in the design of equipment used in harvesting operations and food processing operations. Methods: The experiment was conducted at Department of Agricultural Engineering, Indian Agricultural Research Institute, New Delhi. All the experiments were replicated thrice and mean±SD (standard deviation) values were taken using R software to check the level of significance (p≤0.05). Result: Physical properties, mechanical properties and germination of pulses were evaluated as functions of moisture content. It was observed that average length, breadth, thickness and geometric mean diameter, sphericity, porosity, angle of repose and static coefficient of friction of pulses increased linearly and bulk density, true density, hardness and germination decreased density with increase in moisture content from 9.98 to 20.4% (db).
Penggunaan Sistem Informasi Penilaian Kinerja Berbasis SIEKA Hubungannya Dengan Kinerja Pegawai
Authors: Rahmadita Annisa , Badrudin Badrudin , Dian Dian
Published: July 2023

The design and implementation of the educational curriculum must be adapted to the socio-cultural conditions of an educational institution. Therefore, in implementing the curriculum, it is better to use appropriate socio-cultural management so that quality development goes well even though it is in educational institutions that have a strong religious system or known as pesantren. The purpose of this research is to know the planning, implementation and evaluation of curriculum based on socio-cultural management in the area of pesantren-based social institutions. This research is a qualitative with the type of case study. Sources of data used are primary and secondary. Data collection techniques in the form of observation and interviews. Data analysis used qualitative data analysis according to Miles and Huberman. The result of this research is that curriculum planning carried out by MTs Nurul Iman Garum is carried out with a process towards a better direction in terms of learning and institutions. In addition, the implementation of the curriculum includes checking teacher readiness, the learning process is supervised by the head of the madrasa, there is an instillation of Islamic values in the learning process, implementing the ubudiyah program, the tahfidz program or additional tutoring. For the evaluation carried out by the MTs Nurul Iman Garum institution, namely; there are two evaluations to measure students' abilities, namely summative and formative evaluations.