bluuebunny/crossref_metadata_2025 huggingface dataset:
Bajo el puente
Authors: Acero Andres , Cazares Xavier
Published: August 2023

Una mañana de lunes, como en cualquier semana, abrí mi ventana esperando ver el hermoso paisaje de mi pueblo, Poza Rica. Pero, esta mañana, a diferencia de las otras 5000 que habré pasado a lo largo de mi vida, el sol ya no estaba ahí. Una sombra oscura era lo que veían mis ojos que poco a poco se llenaban de lágrimas como consecuencia del humo, el olor a concreto y la arena que inundaba todo el aire. Solo podía oír las grandes máquinas rompiendo, martillando y decidiendo con cada golpe el futuro de este pueblo. Tristes, mi perro y yo cerramos la ventana sin mucha esperanza de que fuera un buen día.
Sinergistas para el trampeo del picudo del agave Scyphophorus acupunctatus (Coleoptera: Dryophthoridae) en Agave angustifolia (Asparagaceae) en Guerrero, México
Authors: Cuevas-López Daniel , Hernández-Castro Elías , Romero-Rosales Teolincacihuatl , Segura-Pacheco Héctor Ramón , Figueroa-Castro Pedro , Gonzalez-Hernádez Héctor
Published: August 2023

Scyphophorus acupunctatus (Coleoptera: Dryophthoridae), ataca diversas especies de agaves silvestres y cultivados en México. El manejo de este insecto se dificulta debido a sus hábitos de alimentación en tallos y hojas de agave. Recientemente, se ha desarrollado un sistema de trampeo basado en feromona de agregación sintética y cebo alimenticio para monitorear y capturar al adulto de S. acupunctatus. Sin embargo, es importante determinar algunas alternativas que puedan sinergizar la respuesta de S. acupunctatus a la feromona sintética. En este estudio se realizaron dos ensayos de campo consecutivos donde se evaluaron diversos sinergistas en trampas colocadas en una plantación de Agave angustifolia (Asparagaceae), en Quetzalapa, Guerrero, México. Los sinergistas evaluados fueron: tejido vegetal de A. angustifolia, frutos de piña (Ananas comosus) madura, plátano (Musa paradisiaca) y un sinergista sintético (Sinergium®). En todos los experimentos se utilizó un diseño completamente al azar, con cuatro repeticiones de cada tratamiento. Los sinergistas evaluados no tuvieron efecto en las capturas de S. acupunctatus en trampas. Los promedios de captura de S. acupunctatus/trampa/día en los experimentos no tuvieron diferencias, por lo que se sugiere que en plantaciones con infestaciones iniciales o bajas (hasta 5 picudos) no se requiere adicionar sinergistas, mientras que a densidades altas (más de 5 picudos) es recomendable utilizar algún sinergista vegetal o el sintético (Sinergium®) para hacer sinergia con la feromona sintética. Adicionalmente, se capturaron más hembras (192) que machos (137), esto puede impactar en las densidades poblacionales siguientes del picudo, la sanidad de la planta y la economía del productor.
DIREITOS ESCOLARES E EDUCAÇÃO INCLUSIVA
Authors: De Souza Vinícius Garcia Rodrigues , Rodrigues Thiago Donda
Published: August 2023

O objetivo deste estudo é analisar o estado da arte na garantia da educação inclusiva. Por meio de pesquisa bibliográfica em fontes que tratam deste tema, pretende-se demonstrar que o acesso à educação inclusiva também é um dos aspectos do direito humano fundamental que vem sendo conquistado ao longo dos anos. Concluindo que este é um direito que possibilita ao cidadão meios de abertura para sua autoconstrução, além de ampliar sua capacidade de participação nos destinos da sociedade onde vive, portanto, é também um direito social. O direito à educação inclusiva é um tema bastante debatido e, em face da busca pela universalização da educação inclusiva, tem sido considerado como um dos pilares da luta pelo desenvolvimento humano, responsável pela melhoria da qualidade de vida das pessoas. Desse modo, o direito à educação se apresenta também como um direito público social capaz de promover a democratização da sociedade, por isso mesmo, é um direito para todos, além do indivíduo, pois beneficia toda a coletividade, portanto, um dever do Estado. Os elementos que fundamentam o texto foram extraídos do conteúdo oferecido na disciplina Educação Contemporânea Brasileira. Também foi necessário buscar um breve histórico dos direitos fundamentais e sobre a legislação brasileira que assegura o direito à educação a ser garantido pelo Estado, o capítulo seguinte trata da importância da cidadania para o desenvolvimento da criança, o terceiro capítulo aborda a inclusão escolar e a formação da cidadania, por fim são feitas as considerações finais deste estudo.
Once again about the mechanism of administrative coercion
Authors: Kurakin Aleksei Valentinovich
Published: August 2023

The article discusses the mechanism of administrative coercion, this issue is important from the point of view of the application of various measures of administrative influence. The importance of such a category as the "legal mechanism of administrative coercion" will be predetermined by its functionality in determining methods of coercive influence. The mechanism of application of administrative coercion may make it possible to balance private and public interests in the application of various measures of administrative coercion, as well as to avoid violations of the requirements of legality. The mechanism of administrative coercion is a kind of law enforcement (police) mechanism. Despite this, the mechanism of coercion has its own specifics. The author revealed the features of the mechanism of administrative coercion measures, gave a theoretical analysis of the elements of this mechanism. The paper draws attention to the fact that constructively the mechanism of administrative and legal regulation of the use of coercive measures includes the norms of law, legal relations, acts of application of the norms of law, as well as legal culture. Based on this, the author concludes that the mechanism of action of administrative coercion harmoniously includes both legal and non-legal elements, and the importance of the latter elements is also important for the effectiveness of the implementation of the coercion. The author concluded that the legal culture as an element of the mechanism of administrative coercion has not received a proper theoretical assessment.
Fix and replace technique in elderly acetabular fractures
Authors: Delgadillo Camilo A. , Pesantez Rodrigo
Published: August 2023

Fragility fractures in the pelvis and lower limbs increase morbidity and mortality. The surgical treatment and rehabilitation of acetabular fractures in the elderly are challenging due to weight-bearing limitations. With the “fix and replace” technique, the combined management of open reduction and internal fixation of the acetabular fracture and total hip replacement could be beneficial, having high consolidation rates, long prosthesis survival, a mortality rate of 13% and early weight-bearing with good functional outcomes. This publication aimed to review the available literature on treating acetabular fractures in the elderly, with particular attention to the “fix and replace” technique.
BANKING SECTOR OF UKRAINE: ANALYSING FACTORS OF INSOLVENCY, BANKRUPTCY AND BANKS’ LIQUIDATIONS
Authors: Bereslavska Olena
Published: August 2023

The article examines the trends observed in the Ukrainian banking sector, specifically focusing on changes in the number of banks from 1992 to 2023. The factors contributing to the increase in insolvent and bankrupt banks and subsequent liquidation and revocation of banking licenses are analyzed. The study identifies key factors that arise from both internal bank operations in the banking services market and external factors stemming from macroeconomic and political situations. These factors include a significant decline in GDP, currency devaluation, inflation, and military operations within the country. The article discusses the monitoring of current legislation norms that define the criteria for classifying banks as problematic and insolvent by the National Bank of Ukraine. The regulator associates these criteria primarily with internal issues within the bank, such as liquidity standards violations, non-compliance with current legislation and regulatory requirements, and a decrease in regulatory capital. Voluntary and forced liquidation processes are examined within the framework of the current legislation. Voluntary liquidation by bank shareholders allows the bank to maintain its legal entity status. Banks undergoing compulsory liquidation have the option to reorganize through mergers and acquisitions. During the process of cleaning up the banking sector, system banks received substantial government support in the form of financing through bonds. The article argues that the cleansing of the banking system, which took place between 2014 and 2016 and continued in subsequent years, contributed to the stability and efficiency of the banking sector amid the war in Ukraine. The regulator liquidated banks with Russian capital during the hostilities and declared two banks insolvent due to risky operations and failure to repay debts to borrowers. Furthermore, the study concludes that the significant decrease in the number of banks in Ukraine did not impact the growth trend of total assets in the banking system, indicating the sector’s efficiency. Stress testing in three stages is highlighted as a means for determining the actual state of the banking system during times of conflict.
THE ANALYSIS OF THE LEXICAL AND STYLISTIC FEATURES OF THE ENGLISH SUBJECT GROUP WHICH DENOTES ADVERTISING OF THE AUSTRALIAN HOTEL INDUSTRY
Authors: Fabrykina Viktoriia , Kraichynska Halyna
Published: August 2023

The article examines the specifics of the lexical and stylistic features of the functioning of the English thematic group for the designation of advertisements in the Australian hotel industry. The influence of stylistic means and techniques to enhance the overall connotative load of the advertising text of the hotel industry is generalized. Despite the considerable number of linguistic works devoted to the study of various aspects of English texts of the advertising industry, it should be noted that the English thematic group denoting the Australian hotel industry has not yet been the subject of a special linguistic description. The advertising text of the Australian hotel industry is compiled taking into account the ways of dialogization, de-automation of the addressee's perception of the language and the formation of positive emotions. The article is based on the analysis of 90 advertising texts and slogans of the Australian hotel industry (2020-2023). In particular, the following lexical and stylistic means have been identified that are widely used in advertising texts of the Australian hotel industry: hyperbole, metonymy, synecdoche, metaphor, personification, epithet, comparison, synonyms, antithesis. In the advertising texts of the hotel industry, there is a wide range of vocabulary related to the hotel business, food, tableware, hotel rooms (deluxe, standard), excursions, Australian attractions, restaurants, hygiene products, and drinks.
PECULIARITIES OF TRANSLATING ENGLISH NOUN COMPOUNDS INTO UKRAINIAN
Authors: Stakhmych Yuliia
Published: August 2023

The article is devoted to the study of the peculiarities of translating English noun compounds in D. Eggers’ novel “The Circle” into Ukrainian. The approaches to defining the concepts of compounding and compounds were described. One hundred English noun compounds and their Ukrainian equivalents were analyzed, the translation methods of these lexical units were determined. It was established that to convey English noun compounds in the Ukrainian version of D. Eggers’ novel “The Circle” the following translation methods were used: selection of dictionary equivalents (40%), loan translation (39%), explication (11%) and various types of transcoding, in particular: transcription (4%), practical transliteration (2%), mixed transcoding (2%) and adaptive transcoding (2%). Most often, the selection of dictionary equivalents and loan translation were applied, which made it possible to preserve the semantic integrity of the compounds and made them accessible for understanding by Ukrainian readers. Loan translation was also used in cases of conveying the meaning of proper names – occasional author’s formations that contained the word Circle and other components associated with the company. Less common methods were explication and types of transcoding, which contributed to the compactness of the translation, and also helped to preserve the authenticity of the noun compounds used by the author of the novel. To translate the most used N+N structural type of noun compounds from English into Ukrainian, T. Boiko used 5 methods, which are dominated by word combinations in which N1 was translated into adjective. This can be explained by the fact that adjective-noun constructions are more common in the Ukrainian language, unlike English, in which noun-noun constructions are often used.
ANALYSIS OF EFFECTIVE METHODS OF FORMING UKRAINIAN-LANGUAGE COMMUNICATIVE COMPETENCE IN FOREIGN STUDENTS
Authors: Shlenova Maryna
Published: August 2023

This article is devoted to the analysis of effective methods of forming Ukrainian-language communicative competence in foreign students. This problem is important in the modern educational environment due to the growing number of foreign students studying in Ukraine. The necessity of developing and applying effective approaches that help learn Ukrainian language and culture effectively is emphasized. This article analyzes various approaches and innovative technologies used to develop Ukrainian-language communicative competence in foreign students. In particular, the effectiveness of the communicative approach, interactive technologies, and intercultural communication is considered. Multimedia technologies. The study found that the most effective methods are those that combine practical work with the language and use of modern technologies. In addition, an important condition for the successful formation of Ukrainian-language communicative competence is an individual approach to each foreign student and an understanding of his or her personal needs and goals.
FUNCTIONS OF HETEROTOPIES IN CONTEMPORARY UKRAINIAN DRAMATURGY
Authors: Bortnik Zhanna
Published: August 2023

The article reveals the specificity of the heterotopic approach in the analysis of artistic texts and characterizes the functions of heterotopias in modern Ukrainian drama. Examining artistic dramatic texts as «other space» it was found that modern Ukrainian playwrights at the liminal stage resorted to creating the image of a parental house, a village, a provincial town, which realize in the texts the heterotopia function of a prison that breaks time; the heterotopia of the Maidan, Donbass as a museum and archive that accumulates time, and interpreted the current state of the country through the function of the heterotopia of the library in intertextual images, motifs and plots. At the postliminal stage, the heterotopia of the parental house, the town, changed its function to that of a museum. By resorting to heterotopia as an artistic image in dramas, playwrights have the opportunity to highlight the collision of a private and public character, which strengthens the dramaturgical conflict, to demonstrate how the personal spaces of the characters are presented in «other spaces», which helps to realize the specificity of the character of the heroes, they have the opportunity to embody «rituals of transition» between topos and images of “ritual sacrifices” that the characters are ready for in order to go beyond heterotopia. Heterotopias of the subject of broadcasting in modern Ukrainian drama are manifested primarily by the time-spaces of captivity, prison, hospital, educational institution, train, ship. Ukrainian dramaturgy of the post-liminal period, in addition to changing the function of the heterotopia of the parental home, village, town, train, represents the heterotopia of the shelter (bomb shelter). Playwrights actively involve heterotopic images that realize the author's idea of an artistic return of a character to his own past in order to find and reflect on mistakes, to get answers to questions or strength to fight from the past. The hero's past, recorded in memories, has signs of a hermetic space with its internal laws, rituals, interrupts, stops or accumulates time.
Conformationally Flexible Ellagitannins: Conformational Analysis of Davidiin and Punicafolin via DFT Calculation of 1H NMR Coupling Constants
Authors: Matsuo Yosuke , Iki Misato , Okubo Chiho , Saito Yoshinori , Tanaka Takashi
Published: August 2023

Many ellagitannins with various conformations of their glucose moiety have been isolated from natural sources. Here, a conformational analysis was performed via the density functional theory calculation of 1H NMR coupling constants. It was observed that, in the solution state, davidiin exists as an equilibrium mixture of the BO,3 (boat) and 1C4 (chair) conformational states, while punicafolin is an equilibrium mixture of the 3S1 (skew-boat) and 1C4 conformational states. Their equilibrium states changed depending on the solvent and temperature. Such conformational flexibility may be important for the biosynthesis of ellagitannins with diverse structures.
Model selection using replica averaging with Bayesian inference of conformational populations
Authors: Raddi Robert M. , Marshall Tim , Ge Yunhui , Voelz Vincent
Published: August 2023

Bayesian Inference of Conformational Populations (BICePs) is a reweighting algorithm that reconciles simulated ensembles with sparse and/or noisy observables, by sampling the full posterior distribution of conformational populations in the presence of experimental restraints. By modifying BICePs to use replica-averaging in its forward model, BICePs becomes similar to other MaxEnt approaches, but with the significant advantages of (1) being able to sample over the posterior distribution of uncertainties due to random and systematic error, with improved likelihoods to deal with outliers, and (2) having an objective score for model selection, a free energy-like quantity called the BICePs score. To demonstrate the power of our approach, we used BICePs to reweight conformational ensembles of the mini-protein chignolin simulated in nine different force fields with TIP3P water, using a set of 158 experimental measurements (139 NOE distances, 13 chemical shifts, and 6 vicinal $J$-coupling constants for H$^{\text{N}}$ and H$^{\alpha}$. In all cases, reweighted populations favor the correctly folded conformation. The BICePs score, which reports the free energy of "turning on" conformational populations along with experimental restraints, provides a metric to evaluate each force field. For the nine force fields tested (A14SB, A99SB-ildn, A99, A99SBnmr1-ildn, A99SB, C22star, C27, C36, OPLS-aa), we obtain results consistent with previous work that used a conventional $\chi^{2}$ metric for model selection for small polypeptides and ubiquitin (Beauchamp et al 2012). These results suggest a powerful role for BICePs in future applications requiring ensemble reweighting and model selection.
Data Efficient and Stability Indicated Sampling for Developing Reactive Machine Learning Potential to Achieve Ultra-long Simulation in Lithium Metal Batteries
Authors: Xu Longkun , Shao Wei , Jin Haishun , Wang Qiang
Published: August 2023

Modelling the formation of solid-liquid interphase (SEI) is challenging as its strict requirement with both simulation accuracy and length. Machine learning potential (MLP) based molecular dynamics (MD) simulation is expected to play a role in this field while currently its use is hindered by sampling efficiency and simulation stability. In this work, we tackle the two challenges together. We propose the stability-indicatedsampling (SIS) algorithm for efficiently sampling training data using physical information (temperature). Unlike previous strategies, our method does not need prior knowledge of reaction networks or training multiple MLPs for uncertainty estimation. Compared with the recent proposed methods HAIR and DP-GEN, our approach gives significant improvement of sampling efficiency with less requirements with the initial training data, to realize > 10 ns MLPMD simulation using ab initio MD (AIMD) trajectory of just a few ps. We introduce the concept underlying instability consistency by showing the accuracy of reaction mechanisms and radial distribution function (RDF) can be improved by SIS-MLPMD, although their information is not explicitly used in our sampling decision. Furthermore, we show that long-time MLPMD simulation of Lithium metal battery (LMB) can not only reproduce some well-known SEI components including LiF, Li2O, LiOH, LiS and the incomplete N-S breaking in highconcentration systems, but also ionic aggregation structures of LiF, which is not shown in our AIMD training data but matches previous results of electrochemical impedance spectroscopy. Our work is expected to help accelerate future investigations, especially for studying long-time (≥ ns scale) reaction dynamics in interfacial problems.
Regioselective Fluoroalkylarylation of Enamides Enabled by an Iron-Catalyzed Multicomponent Radical Cross-Coupling Strategy
Authors: Rentería-Gómez Ángel , Guerrero Macayla , Ramirez-Lopez Mireya , gutierrez osvaldo
Published: August 2023

Fluoroalkylated compounds are important entities in agrochemicals, pharmaceuticals, and materials. The catalytic dicarbofunctionalization of alkenes represents a powerful strategy for the rapid construction and diversification of compounds. In this vein, multicomponent cross-coupling reactions (MC-CCR) can provide an efficient synthetic route to build molecular complexity. In this work, we report the first iron-catalyzed three-component fluoroalkylarylation of enamides via selective formation and trapping of alpha-amide radicals under mild conditions and fast reaction times. The reaction tolerates a variety of commercially available aryl Grignard reagents and fluoroalkyl halides. Finally, the use of a removable phthalimido group provides an efficient strategy to prepare highly valuable difluoroalkylated amines.
Water sensitivity of heteroepitaxial Cu-MOF films: dissolution and recrystallization of 3D-oriented MOF superstructures
Authors: Brandner Lea A. , Linares-Moreau Mercedes , Amenitsch Heinz , Dal Zilio Simone , Doonan Christian , Falcaro Paolo
Published: August 2023

3D-oriented metal-organic framework (MOF) films and patterns have recently emerged as promising platforms for sensing and photonic applications. These oriented polycrystalline materials are typically prepared by heteroepitaxial growth from aligned inorganic nanostructures and display anisotropic functional properties, such as guest molecule alignment and polarized fluorescence. However, to identify suitable conditions for the integration of these 3D-oriented MOF superstructures into functional devices, the effect of water (gaseous and liquid) on different frameworks should be determined. We note that the hydrolytic stability of these heteroepitaxially grown MOF films is currently unexplored. In this work, we present an in-depth analysis of the structural evolution of aligned 2D and 3D Cu-based MOFs grown from Cu(OH)2 coatings. Specifically, 3D-oriented Cu2L2 and Cu2L2DABCO films (L = 1,4-Benzenedicarboxylic acid, BDC; Biphenyl-4,4-dicarboxylic acid, BPDC, DABCO = 1,4-Diazabicyclo[2.2.2]octane) were exposed to 50% relative humidity (RH), 80% RH and liquid water. The combined use of X-ray diffraction, infrared spectroscopy, and scanning electron microscopy shows that the sensitivity towards humid environments critically depends on the presence of the DABCO pillar ligand. While oriented films of 2D MOF layers stay intact upon exposure to all levels of humidity, hydrolysis of Cu2L2DABCO is observed. In addition, we report that in environments with high water content, 3D-oriented Cu2(BDC)2DABCO recrystallizes as 3D-oriented Cu2(BDC)2. The heteroepitaxial MOF-to-MOF transformation mechanism was studied with in situ synchrotron experiments and time-resolved AFM measurements. These findings provide valuable information on the stability of oriented MOF films for their application in functional devices and highlight the potential for the fabrication of 3D-oriented superstructures via MOF-to-MOF transformations.
Leaky, Dead, and Restless: Afterdeath in Contemporary Venezuelan Fiction
Authors: Troconis Irina R.
Published: August 2023

This article analyzes “Cadáver,” a short story in the collection Barrio bonito (2015), by Venezuelan author Luis Freites. It argues that, rather than creating an afterlife for the dead characterized by processes of mourning, commemoration, and memorialization, the story captures the body’s afterdeath: the slow decomposition and transformation of the corpse from organic matter to bones and dust. Through the staging of an aesthetic gesture described by Maikel—the story’s protagonist—as “mirar pa’dentro” (to look inside or to look into one’s insides), a temporality determined by the tempo of decay, and the multisensory attack of leaky dead matter dripping from the corpse, the afterdeath that materializes in “Cadáver” creates what I, following the work of Michael Rothberg and Venezuelan poet Igor Barreto, call “networks of implication.” These networks build connections between bodies both human and nonhuman based not on empathy, compassion, or familiarity but on contact, contagion, and unsettling moments of intersection and recognition. I propose that, in doing so, they introduce a form of relationality that is not mediated or circumscribed by grief, and that demands a radical renewal of political vocabularies and a reorganization of social life that has, as its core, the collectivization of death.
The language of the in-between. Travestis, post-hegemony and writing. By Erika Almenara. Pittsburgh: University of Pittsburgh Press, 2022
Authors: Sánchez Osores Ignacio
Published: August 2023

Review of Almenara book.
Effect of nitrogen nutrition on yield and yield structure elements of spring barley varieties bred by FRC “Nemchinovka ”
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Dedushev I.A. , Eroshenko L.M. , Pyl ’nev V.V.
Published: August 2023

The response of ten spring barley varieties bred by FRC “Nemchinovka” to increasing nitrogen nutrition has been studied. A positive effect of nitrogen fertilisation on the yield growth and the main elements of barley yield structure was found. The varieties Nadezhnyi, Raushan and Zlatoyar were highly responsive to more intensive nitrogen nutrition.
Factors affecting academic achievement of third-year students of Bursa Uludağ University Faculty of Medicine
Authors: Erer Kafa Sezer , Ladik Merve , Arı Fatma Şeyma , Demirtaş Şerife Büşra , Özkaya Güven , Türkkan Alparslan
Published: August 2023

The present study aimed to investigate the determinants of academic performance among third-year students in the Faculty of Medicine. A survey consisting of 45 questions was administered to 357 third-year students in the academic year 2017-2018, with a response rate of 233 participants. The academic achievement was assessed by evaluating the grade point average (GPA) scores, with a threshold of 3. The results revealed that several factors were significantly associated with a GPA score of 3 and above, including age (p=0.011), relationship with parents and positive parental attitude (p=0.001), staying with family (p=0.015), and school selection to “be a doctor” (p=0.044). The results also showed that negative parenting behaviors and smoking were associated with an increased risk of academic failure. However, no significant association was found between academic performance and gender, physical exercise, parents’ education, and employment status. This study highlights the crucial factors impacting academic achievement in medical education. The results demonstrate the importance of age, relationship with parents, parental attitude, reasons for choosing a medical school, smoking habits, and extracurricular activities in determining GPA outcomes. The findings have important implications for the future planning of students, the development of education, and the formulation of new policies
Pengaruh Metode Whole Brain Teaching dengan Pendekatan Saintifik terhadap Hasil Belajar Siswa pada Materi Statistika Kelas VIII SMP Negeri 11 Mataram Tahun Ajaran 2022/2023
Authors: Cahya Ramdhani Eka Putri , Arjudin Arjudin , Tyaningsih Ratna Yulis , Sridana Nyoman
Published: August 2023

Matematika adalah salah satu mata pelajaran yang harus diajarkan pada setiap tingkat pendidikan dasar dan menengah karena memiliki peran penting dalam kemajuan ilmu pengetahuan dan inovasi. Untuk memperoleh hasil belajar matematika yang optimal, diperlukan penerapan metode atau pendekatan yang sesuai dengan karakteristik siswa dan materi yang diajarkan. Penelitian ini bertujuan untuk mengetahui pengaruh dari metode Whole Brain Teaching dengan pendekatan saintifik terhadap hasil belajar siswa pada materi statistika kelas VIII SMP Negeri 11 Mataram. Penelitian ini merupakan penelitian eksperimen semu dengan pendekatan kuantitatif. Populasi dalam penelitian ini yaitu siswa kelas VIII SMP Negeri 11 Mataram tahun ajaran 2022/2023 dengan sampel kelas VIII A dan VIII C yang dipilih menggunakan teknik cluster sampling. Instrumen penelitian berupa lembar observasi dan lembar tes hasil belajar. Teknik analisis data yang digunakan adalah uji prasyarat dan uji hipotesis. Hasil analisis data menunjukkan bahwa rata-rata hasil belajar kelas yang menggunakan metode Whole Brain Teaching dengan pendekatan saintifik yaitu 71.407 lebih besar dari rata-rata hasil belajar kelas yang menggunakan metode ekspositori yaitu 54.814. Kelas yang diberi perlakuan menggunakan metode Whole Brain Teaching dengan pendekatan saintifik memiliki rata-rata lebih besar, maka dapat disimpulkan bahwa terdapat pengaruh metode Whole Brain Teaching dengan pendekatan saintifik terhadap hasil belajar siswa pada materi statistika kelas VIII SMP Negeri 11 Mataram tahun ajaran 2022/2023.
Correlation of dry eye symptoms and young adult riders.
Authors: Asif Mashood Qazi  , Arsalan Ahmed Rajput  , Azfar Ahmed Mirza  , Israr Ahmed Bhutto  , Abdul Haleem  , Munawwar Hussain
Published: August 2023

Objective: To correlate the symptoms of dry eye with young adult riders. Study Design: Cross-sectional study. Setting: Al-Tibri Medical College, Isra University, Karachi. Period: December 2020 to November 2021. Material & Methods: 60 young riders with dry eyes between the age of 21-30 years were included in the study and their duration of years in riding bike, duration of riding bike a day, and lastly the symptoms were recorded. Data was analyzed using SPSS version 24.0 and the correlation was assessed using Pearson’s correlation. The level of significance was set at P<0.05. Results: The mean age of the riders were 25.46 ± 0.12. 70% of the riders were riding for more than 5 years, 23.3% riders were riding for more than 2 years, while only 6.7% were riding for less than 2 years. 36.1% riders rode for >8 hours/day, 26.7% for >6 hours/day, 21.7% for >4 hours/day, and 15% for 2 hours/day. Symptoms of dryness, burning, itching, crusting, blurring, and redness all showed significant difference with the duration of years as a rider as well as the number of hours the rider rode during the day. Conclusion: Dry eye symptoms significantly correlate with young adult riders and the appropriate intervention is required to treat it accordingly.
Comparison of effects of administering warmed vs normal temperature intravenous fluids on body core temperature in surgical individuals.
Authors: Viqar Aslam  , Muhammad Bilal  , Muhammad Ayaz  , Shabir Hasan  , Alina Zaidi  , Lubna Gul
Published: August 2023

Objective: This study was designed to evaluate the impact of different temperatures of intravenous fluids on the body. Study Design: Randomized Experiment. Setting: LRH Peshawar. Period: April 2022 to January 2023. Material & Methods: 600 individuals were scheduled for abdominal surgery to include them in the study. Two groups were made using sealed, opaque envelopes carrying randomly generated computer numbers. The patient's body temperature, O2 saturation,, heart rate, shivering, blood pressure and fluid intake were all monitored and recorded on two point i)when he was admitted to the PAR and ii) one and a half hour later. The classification developed by Crossley and Mahajan was used to determine the level of shivering. With SPSS 23, the t test and Mann-Whitney U test were used to evaluate data. Results: The mean age of the intervention group was 38.30 years, compared to 37.64 years for the control group. After 30 minutes, the average temperature difference among the two groups on admission to PAR was statistically significant. No discernible difference existed between the levels of pain of two groups. Time to return to work was reported to differ significantly. For factors like SpO2, systolic and diastolic blood pressure, and respiratory rate, no discernible difference was discovered. Conclusion: After administering warm fluids intravenously, there is a fall in the intervention group's shivering.
Correlation of monocytopenia with aging in COVID-19 infected patients.
Authors: Sana Rasheed Chaudhry  , Zunnera Rashid  , Erum Rashid  , Sabeen Shakir  , Aenza Asif  , Faiza Rasheed
Published: August 2023

Objectives: To observe the effect of aging on monocyte count in COVID-19 infected patients. Study Design: Observational study. Setting: Rawal Institute of Health Sciences Islamabad, Pakistan Institute of Medical Sciences Islamabad. Period: April 2021 till July 2021. Material & Methods: Adult humans of total 100 in numbers, suffering from corona virus with positive PCR test were selected. They were divided in two groups with 50 patients in group A and 50 patients in group B. Inclusion criteria was COVID-19 infected patients belonging to both genders without any blood disorder. All adults below the age of 18 years with blood disorder diseases were excluded. The age limit in group A was below 50 years and in group B was above 50 years. Monocyte count of all the patients was noted from the record in the laboratory of Rawal institute of health sciences and Pakistan institute of Medical sciences Islamabad. The age of the patients was confirmed from their CNIC. Results: Data was checked for normality by using Shapirowilk test of normality and comparison of monocyte count in between two groups was done by using Mann Whitney U test a significant difference was seen. Monocyte count in group A was 172/ µl and in group B was 122/ µl of blood. The mean age in group A was 32.3 years and in group B was 65.9 years. The p value of 0.00 shows a significant correlation of aging with monocytopenia. Conclusion: Corona virus infected patients with increased age (> 50) years showed more reduction in monocyte count as compared to patients with lower age (< 50) years.
Efficacy and safety of oral ivermectin combined with topical permethrin in treatment of scabies.
Authors: Saman Iqbal Goraya  , Safoora Aamir  , Beenish Jabeen Bajwa  , Beenish Rahat  , Tassmia Afzal  , Riffat Naseem
Published: August 2023

Objective: To determine the efficacy and safety of oral ivermectin and topical permethrin when given either alone or in combination in patients with scabies. Study Design: Randomized Controlled Trial. Setting: Department of Dermatology, Sheikh Zayed Hospital, Lahore. Period: April, 2022 to September, 2022. Material & Methods: A total of 369 patients with scabies, age 18-60 years and both genders were enrolled after taking written informed consent and were randomly and equally divided into three groups. Group A received 5% topical permethrin, Group B received oral Ivermectin and Group C received a combination of topical permethrin and oral ivermectin. Efficacy and safety was assessed over 3 weeks. Results: The mean age of the patients was 4110.9. There were 164 (44.4%) males and 205 (55.6%) females. The treatment in Group A, B and C was efficacious in 70.7%, 67.5% and 84.6% patients respectively and there was a significant difference between Group A versus C (p=0.009) and Group B versus C (p=0.002). In terms of side effects, 11.4% patients in Group A, 13% in Group B and 17% in Group C experienced side effects. Conclusion: The combination therapy was more efficacious than either treatment alone in patients with scabies, however, the side effects were more compared to single agent.
IMPACTOS DE UM PROTOCOLO DE ATIVIDADE FÍSICA NA SAÚDE MENTAL EM INDIVÍDUO COM TRANSTORNO DEPRESSIVO
Authors: Costa Rodrigo Negrão , Coelho Higson Rodrigues , Cardoso Alcicley Mendes , Bastos Mírian Letícia Carmo
Published: August 2023

Sem!
ARCO DE MAGUEREZ NO DESENVOLVIMENTO DE UM PORTFÓLIO PARA O ENSINO DE FARMACOLOGIA: UM RELATO DE EXPERIÊNCIA
Authors: Bastos Mírian Letícia Carmo , Moreira Ana Carolina Louzada , Dantas Amanda da Silva , Santos Arthur Valente dos , Moreira Edinaldo Benedito Sousa , Pinto Jamily Suelen Cardoso , Borges Renata Campos de Sousa , Medeiros Lauany Silva de , Silva Laís Araújo Tavares , Dolabela Maria Fâni
Published: August 2023

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A IMPORTÂNCIA DA EDUCAÇÃO EM SAÚDE PARA O ENFRENTAMENTO DA HANSENÍASE: UM RELATO DE EXPERIÊNCIA
Authors: Barbosa Andressa Alves , Ferreira Giovana Shulz Vieira , Caldeira Iara da Silva Antunes , Carmo Jhennifer Oliveira do , Portilho João Pedro Moia , Costa Kálita Rayssa Souza da , Anjos Daniele Lima dos , Souza Julyany Rocha Barrozo de
Published: August 2023

Sem!
Bipolar and Goldenhar: A Case Report of Bipolar Disorder with Psychotic Features in a Man with Goldenhar Syndrome
Authors: Mahin Eslami Shahrbabaki , Roya Pooyanfard , Mohammadamin Abdi
Published: August 2023

Background: Goldenhar syndrome is a congenital condition primarily affecting eye, ear, and spine development. In some cases, it can also impact the heart, lungs, kidneys, and central nervous system. The exact cause of Goldenhar syndrome is not fully understood, and its incidence is estimated to range from 1 in 3500 to 1 in 5600 live births. While intellectual disability is associated with the condition, no established link exists between Goldenhar syndrome and psychiatric disorders. Case presentation: In the presented case, a patient with Goldenhar syndrome has been diagnosed with an episode of mania with psychotic features in the context of bipolar disorder. The patient had no history of prior mental disorders and had an independent life. Discussion: There are few case reports of Goldenhar syndrome patients with mental disorders. In all instances, including our own case, patients exhibited psychotic features during psychiatric examinations. Conclusion: Based on the studies cited and our own research, it is recommended to further investigate the potential association between this syndrome and psychiatric disorders. The following sections provide details on the examination, medical history, and treatment of this patient.
HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings
Authors: Mehendale Felicity V , Clayton Gillian , Homyer Kate M , Reynolds Darren M
Published: August 2023

Disinfection is a mainstay of infection prevention, the importance of which was highlighted throughout the SARS-CoV-2 pandemic. There is frequent misuse of terminology surrounding chlorine solutions in the literature. This leads not only to confusion but has potentially dangerous outcomes, as inappropriate mixing of chlorine solutions with other disinfectants or cleaning solutions can lead to the release of chlorine gas. This article provides a resource for accurate terminology surrounding chlorine-based disinfection and clarifies some of the key inaccuracies, including the pH-dependent nature of chlorine species distribution of hypochlorous acid (HOCl) (neutral/acidic chlorine solution) and hypochlorite (OCl-) (alkaline chlorine solution). Misuse and misunderstanding of chlorine solutions and the terminology used can be harmful therefore this is an essential resource for those utilising chlorine as a disinfectant.
Formación de Agujeros Negros a través de colisiones de estrellas de la secuencia principal en cúmulos primordiales con un potencial de fondo (formation of black holes via collisions of main-sequence stars in primordial clusters with a background potential).
Authors:   , Schleicher Dominik
Published: August 2023

La asombrosa existencia de agujeros negros supermasivos en el Universo primitivo es uno de los grandes misterios sin respuesta en astrofísica, en particular, cómo obtienen sus grandes masas tan rápido. Aquí nuestro interés consiste en explorar un nuevo escenario de formación de agujeros negros masivos: la formación por colisiones estelares catastróficas en cúmulos estelares densos. Nuestros sistemas están localizados en el universo temprano, con las denominadas estrellas de población III las cuales son muy masivas y, por tanto, cúmulos de estrellas de población III son sistemas estelares muy densos y masivos. Las simulaciones de N cuerpos fueron corridas con el código NBODY6++GPU y pueden ser divididas en dos grupos, uno con potencial de fondo y otro sin potencial de fondo. Se ha establecido una masa crítica para la cual el número de colisiones es tan alto que puede llegar a formar agujeros negros masivos al interior de estos cúmulos estelares nucleares. Aquí, nuestro objetivo es testear la existencia de esta masa crítica en un caso simplificado de cúmulos de estrellas de población III de igual masa. En términos de la eficiencia para la formación de un objeto masivo, encontramos que ocurre una transición, ya que la eficiencia es muy pequeña para masas considerablemente por debajo del valor de masa crítica, alcanzando valores de ∼ 20% una vez que comenzamos a acercarnos a la escala de masa crítica en nuestras simulaciones. Nuestros resultados sugieren que ocurre una transición crítica dependiendo de la masa del cúmulo y los objetos más masivos alcanzan masas de aproximadamente 1.7 × 105M.
Actividad antibacteriana y biocompatibilidad de nanopartículas funcionalizadas como desinfección en neoterapias endodónticas.
Authors:   , Sánchez Sanhueza Gabriela
Published: August 2023

Introducción: En endodoncia, existen múltiples infecciones de origen bacteriano, que provocan una enfermedad común conocida como periodontitis apical. Por consiguiente, el objetivo principal de los tratamientos en endodoncia es tratar o prevenir el desarrollo de lesiones perirradiculares asociadas a esta enfermedad, mediante la erradicación del componente bacteriano durante la preparación quimio-mecánica. Sin embargo, la tasa de éxito de dientes con estas lesiones alcanza un 85%, disminuyendo a un 68% en los retratamientos. En consecuencia, existe una búsqueda constante de nuevos materiales que puedan contribuir a mejorar la tasa de éxito de la terapia endodóntica. Desde esta perspectiva, basándonos en las beneficiosas propiedades y características antibacterianas y de biocompatibilidad de las nanopartículas metálicas, estas pueden ser una alternativa o coadyuvante a los protocolos actuales como nuevas terapias de desinfección. Objetivo: El objetivo de este estudio fue evaluar la actividad antibacteriana y la biocompatibilidad de nanogeles nanoestructurados de cobre y plata combinados con una matriz polimérica de PVA/PVP. Metodología: En primer lugar, se realizó un screening de la actividad antibacteriana de los nanogeles mediante la determinación de la cinética de muerte por el test de contacto directo frente a Enterococcus faecalis, seleccionando los nanogeles con mayor actividad antibacteriana. En segundo lugar, utilizando un modelo de diente ex vivo con una biopelícula bacteriana multiespecie madura de 21 días, se cuantificó la viabilidad bacteriana postratamiento de los nanogeles por medio de microscopia confocal; además, mediante, el uso de células humanas del ligamento periodontal y de la plataforma de célula viva en tiempo real IncuCyte S3 fue posible evaluar la biocompatibilidad de los nanogeles. Resultados y Conclusión: Este es el primer reporte en el cual se evalúan nanopartículas de cobre y plata estabilizadas con matrices poliméricas de PVA/PVP (nanogeles) en biopelículas bacterianas endodónticas multiespecies y la citotoxicidad empleando la plataforma de célula viva en tiempo real IncuCyte S3. Dentro de los resultados obtenidos en este estudio con relación a la actividad antibacteriana y la citotoxicidad de los nanogeles testeados, evidenciaron que el tiempo de utilización óptimo de estos nanomateriales frente a una biopelícula bacteriana endodóntica multiespecie, es a las 168 h. Asimismo, a medida aumentan los tiempos de acción frente a las células humanas del ligamento periodontal disminuye la citotoxicidad de los nanogeles, proporcionando un material alternativo al hidróxido de calcio durante la medicación en los tratamientos de conductos.
Role of F-box WD Repeat Domain Containing 7 in Type 1 Diabetes
Authors: Mohammed Sarah W. , Qassam Zainab M. , Taha Ekhlass M. , Salih Nameer M.
Published: August 2023

Type I diabetes (T1DM) is a chronic immune system disease characterized by the devastation or injury of ß-cells in the Langerhans Island, resulting in insulin deficiency and hyperglycemia. This study determines the new marker F-box and WD repeat domain containing 7 (FBXW7). One hundred twenty type 1 diabetic patients from three different places (central child hospital, Alkindi center for diabetes and endocrinology, Children’s Education Hospital) in Iraq during the period from (20 December 2021 to 25 March 2022) an age ranges of (4-17) years. The patient group consisted of being derived to three groups: group one healthy patient group (33) was included as healthy patient, group two (20) newly diagnosed T1DM and (67) type 1 diabetic with insulin treatment. The quantitative enzyme-linked immunosorbent assay (ELISA) biochemical parameters were used to quantify the protein FBXW-7 levels. FBG, Cholesterol, Triglyceride, HDL, LDL, VLDL, HbA1c, GOT, GPT, Total Oxidant status, and Total Antioxidant status were measured through spectrophotometry. Serum FBXW-7 protein levels were considerably elevated noticeably (p-value = 0.00). In terms of FBXW7 protein, there was a significant variation between the new and therapy groups. There was no significant variation in protein levels between the new compared to healthy groups. Serum FBXW-7 protein was positively correlated with FBG, TG, cholesterol, GOT, GPT, LDL, and VLDL, and was negatively correlated with HDL in the patient group. According to ROC analysis, the cutoff value for FBXW-7 protein was (1.9) in the newly group and (2.1) in the treatment group. Levels of FBXW-7 protein are elevated in DM patients. FBXW-7 protein was significantly different in the treatment group but not different in the newly group when compared with the healthy group.
Synthesis, Characterization and Biological Activity Study for Some New Metals Complexes with (3Z,3'E)-3,3'-(((2E,5E)-hexane-2,5-diylidene)bis(hydrazine-2,1-diylidene))bis(indolin-2-one)
Authors: Abd AL_Qadir Nuha Ayad , Shaalan Naser Dheyaa
Published: August 2023

Our recent work displays the successful preparation of Schiff_bases that carried out between hexane-2,5-dione and 2 moles of (Z)-3-hydrazineylideneindolin-2-one forming in Schiff-bases-(L), Which in turn allowed combining with each of the next metal ions: (M2+) = Ni, Mn, Zn, Cu and Co forming complexes_ in high stability. The formation of resulting Schiff_ bases (L) is detected spectrally using LC_Mss which gave approximately matching results with theoretical incomes, 1HNMR proves the founding of doublet signal of (2H) for 2NH, FTIR indicates the occurrence of two interfered imine bands and UV-VIS mean is also indecates the formation of ligand. On the other hand, complexes-based-Schiff were characterized using the same spectral means that relied Schiff-bases_(L). Those means gave satisfactory results and proved the distinguishable geometries that suggested. Finally, and according to the antibiotic feature of Schiff-bases and its metal ions we have also examined such character against (-Bacteria and +Bacteria) giving an acceptable inhibition efficiency.