bluuebunny/crossref_metadata_2025 huggingface dataset:
Abdominal Aortic KLF4 Expression in Hyperlipidemic Rabbits: Impact of Colchicine Regimens
Authors: Mylonas Konstantinos S. , Kapelouzou Alkistis , Bakoyiannis Christos , Schizas Dimitrios , Iliopoulos Dimitrios , Nikiteas Nikolaos
Published: January 2025

Aim: Inflammatory regulation of KLF4 has been implicated in atherogenesis. This study examines the effects of colchicine-based regimens on abdominal aortic atheromatosis and KLF4 expression in a hyperlipidemic rabbit model.
Methods: 28 New Zealand White rabbits were divided into four groups. The control group (n = 6) received standard chow, group A (n = 6) was fed chow enriched with 1% cholesterol, group B (n = 8) received the same diet with 2 mg/kg/day colchicine and 250 mg/kg/day fenofibrate, and group C (n = 8) received colchicine and 15 mg/kg/day N-acetylcysteine. After seven weeks, all animals were euthanized, and their abdominal aortas were analyzed. Atherosclerotic plaque extent was assessed morphometrically and KLF4 expression was measured by qRT-PCR.
Results: Group A showed significantly more extensive atherosclerosis than group B (MD: 12.6, 95% CI: 7.1 to 18.2) and group C (MD: 23.8, 95% CI: 18.2 to 29.3). Colchicine combined with N-acetylcysteine reduced plaque extent more effectively than colchicine/fibrate (MD: 11.1, 95% CI: 6.0–16.3). For KLF4, no difference was found between controls and group A (MD: 0.68, 95% CI: -1.77 to 3.14, p > 0.05), but KLF4 was significantly higher in both treated groups (CD vs CD+Col+Fib: MD: -2.45, p = 0.03; CD vs CD+Col+NAC: MD: -2.70, p = 0.03). Colchicine regimens exerted similar effects on KLF4 expression (MD: -0.24, p>0.05).
Conclusions: Colchicine-based regimens effectively reduced abdominal aortic atherogenesis and modulated KLF4 expression in this hyperlipidemic model, suggesting potential therapeutic benefits for abdominal aortic atherosclerosis.
Generative AI in sport and exercise psychology: Exploring opportunities and overcoming challenges
Authors: Oliver Alex , Guiller Jane
Published: January 2025

Sport and Exercise Psychologists are required to remain aware of technological advances and the impact that these may have on their profession. Artificial Intelligence (AI), and in particular Generative AI (GenAI), has become available to the general public and has widespread use much like the rise of the internet in the late 1990s. This advancement in technology has created new challenges for Psychologists – whether they are in practice or academia. Like the internet, AI tools may be a double-edged sword and have the potential to disrupt both the academic and applied practice of psychologists, offering both challenges and opportunities for the field. Therefore, it is important that Psychologists develop AI literacy so that they are equipped with knowledge on the functionalities of AI and understand the ethical implications for its use. In particular, knowledge of the underlying systems, their general principles, and the ways in which they have developed ‘knowledge’ are crucial for navigating AI whether it is to be integrated into practice or not. The aim of this paper is to discuss the potential transformation and innovation in practice provided by AI and argues that for this to be achieved the development of AI literacy is the starting point.
Avaliação dos conhecimentos e crenças associados ao Transtorno de Déficit de Atenção e Hiperatividade (TDAH)
Authors: Vilas Boas Belarmino Mariana
Published: January 2025

Introdução: O artigo apresenta como foco de pesquisa avaliar o conhecimento da população em geral, na faixa etária de 21 a 50 anos, sobre o Transtorno de Déficit de Atenção e Hiperatividade (TDAH) e analisar os estereótipos que a sociedade cria e reproduz sobre o transtorno. Métodos: 400 indivíduos, responderam de maneira online, o questionário de Conhecimento e Crenças sobre o TDAH aplicado por KOS et al. (2004). Discussão: esse questionário foi utilizado de forma modificada, para se adequar a amostra de população diferente. Essas respostas foram investigadas, a partir da análise categorial de conteúdo de Bardin (2011) e relacionadas com os dados sociodemográficos dos participantes. Resultados: todos os entrevistados relataram algumas crenças não respaldadas cientificamente, que podem influenciar para diagnóstico e tratamento inadequados, e perpetuar os estigmas e preconceitos sobre os indivíduos portadores desse transtorno.
Caracterização de rejeito de caulim da região amazônica para uso como pozolana em cimento composto
Authors: Queiroz Nilton Cesar Almeida , Fernandez Oscar Jesus Choque , Cunha Rodrigo Rodrigues da , Queiroz Syme Regina Souza , Picanço Marcelo de Souza , Macêdo Alcebíades Negrão
Published: January 2025

O Estado do Pará, Brasil, concentra grandes empresas que produzem caulim no Brasil, porem também são grandes geradores de resíduos de caulim, produzidos no processo de beneficiamento. Os rejeitos de caulim (RC) estão constituídos basicamente de quartzo proveniente do desareamento assim como dos provenientes dos processos de centrifugação, separação magnética, branqueamento e filtragem.  O presente trabalho apresenta a caracterização do rejeito de caulim proveniente da planta industrial localizada no município de Barcarena/PA, visando sua utilização como pozolânica na matriz de cimento. Foram realizados ensaios físicos, químicos e minerológicos, assim como tratamentos térmicos em temperaturas de 450ºC até 1000ºC, além de ensaios mecânicos para determinação dos Índices das Atividades Pozolanicas (IAP) do RC para todos os intervalos de temparura e do material in natura. O rejeito possue caulinita maioritária, elevados teores de Al2O3 e SiO2 e granulometria argilosa. Térmicamente a caulinita do RC se modifica estruturalmente entre 550 a 750ºC, formando compostos amorfos, considerados pozolanicos. Os testes de IAP com cal e cimento superam as resistências mínimas estabelecidas pelas normas, quando o RC calcinado em 700ºC, resultados esses que indicam a utilização desse RC como pozolana na produção de cimento Portland.
Zonas de sacrifício no Rio de Janeiro: resistências e re(existências) nas Baías de Guanabara e Sepetiba
Authors: Plácido Patrícia de Oliveira , Castro Elza Maria Neffa Vieir de , Leandro Luiz Alberto de Lima
Published: January 2025

Este estudo analisa os pescadores artesanais das Baías de Sepetiba e Guanabara (RJ) frente aos tensores sociais (Estado e indústria), destacando projetos e ações alinhados à sustentabilidade democrática (Acselrad, 2001). Enfatiza a conservação ambiental, a geração de trabalho e renda e as reivindicações sociais dos pescadores, que demandam políticas públicas democráticas para superar a desigualdade social e a degradação ambiental impostas pelo sistema do capital. Discute resistências contra-hegemônicas em zonas de sacrifício (Acselrad, 2004), com foco em desenvolvimentismo, território e sustentabilidade democrática. Baseia-se em abordagem qualitativa e fontes documentais, vinculado ao PELD-Guanabara (UFRJ/CNPq) e ao PPGMA/UERJ. Insere-se em pesquisas sobre conhecimento e experiências formativas voltadas à inclusão política, social e econômica, relacionadas às políticas de desenvolvimento local sustentáveis.
Desenvolvimento de competências para a indústria 4.0 em ambiente educacional
Authors: Lang Carlos Henrique , Frantz Julio Cesar , Kormann Eliane , Gripa Sidnei , Rosa Josely Cristiane
Published: January 2025

A Indústria 4.0 caracteriza-se pela integração de tecnologias de automação com o intuito de otimizar processos produtivos, aumentar a eficiência e reduzir custos operacionais, elevando os padrões de qualidade. Nesse cenário, a robótica emerge como um elemento central, desempenhando um papel indispensável na produção industrial em larga escala. Este estudo investiga o uso da robótica como ferramenta para o desenvolvimento de habilidades essenciais à Indústria 4.0, como a integração de equipamentos e conhecimentos em eletrônica e software, utilizando um robô educacional em atividades simuladas. O objetivo da pesquisa foi empregar conceitos robóticos em simulações industriais para promover a capacitação de conhecimentos em um ambiente educacional controlado. Foram constituídos dois grupos de participantes: o primeiro composto por alunos que cursaram robótica durante a graduação de Engenharia Mecânica, e o segundo formado por alunos do curso que não receberam essa formação. As oficinas utilizadas para conceituar os participantes, seguiram a seguinte estrutura metodológica: introdução aos conceitos robóticos e ao robô, seguida pela programação em blocos e simulação dos estudos de caso. No primeiro, simulou-se uma operação industrial de pick-and-place com uma garra de sucção a vácuo, replicando processos de paletização. O segundo estudo introduziu uma esteira transportadora e um sensor fotoelétrico. Após as oficinas, um questionário avaliou o impacto do conhecimento prévio em robótica e o aprendizado adquirido durante as atividades. Os resultados demonstraram que o grupo com conhecimento prévio apresentou maior facilidade na execução das tarefas; ainda assim, ambos os grupos avaliaram as oficinas de forma positiva.
Pengaruh Sistem Pengendalian Intern, Sistem Informasi Akuntansi, Dan Komitmen Organisasi Terhadap Akuntabilitas Pengelolaan Alokasi Dana Desa Pada Desa-Desa di Kecamatan Kupang Tengah
Authors: Abdon Lodowik Tasesab  , Yohanes Demu  , Maria Prudensiana L. Muga
Published: January 2025

This research aims to determine the influence of the internal control system, accounting information system, and organizational commitment on the accountability of village fund allocation management in villages in the Kupang Tengah District. The data used in this research are primary and secondary data. The data obtained in this research were collected through questionnaires distributed directly to all village officials in the Kupang Tengah District. This study uses a Quantitative approach with a saturated sampling technique. The data analysis technique used is descriptive statistical analysis, validity test, reliability test, normality test, and hypothesis testing. The analysis tool used is Statistical Package for the Social Sciences 23 (SPSS 23). The results of this study indicate that there is a significant influence of the internal control system, accounting information system, and organizational commitment on the accountability of village fund allocation management.
Program Aplikasi Penerimaan dan Pengeluaran Kas Berbasis Web pada PT Air Minum Tabalong Bersinar (Perseroda)
Authors: Nadia Puteri Utami  , Fitria Fitria  , Khafifah Widya Maharani
Published: January 2025

PT Air Minum Tabalong Bersinar (Perseroda) is a regional-owned business entity engaged in the field of drinking water services for all people in the Tabalong Regency area. A company really needs to carry out internal control over cash receipt and disbursement procedures, because it is related to the continuity of the company's operations. Every day, PT Air Minum Tabalong Bersinar (Perseroda) always supervises cash receipts sourced from water bill income, new connection installations, reconnections, and inspection income. The large amount of cash received every day makes transactions increasingly dense, there is no application to process cash filling and disbursement data, so the calculations are inaccurate, and it is difficult to present cash receipt and disbursement reports briefly. In addition, the problems that occur in cash management, PT Air Minum Tabalong Bersinar (Perseroda) still does the manual method, namely by entering cash receipts and disbursements in Microsoft Excel, and recapitulating data every day by entering it into the table provided. This is less effective and efficient, because it does not shorten the processing time at all and can be risky for data that has not been entered due to unsystematic presentation. Therefore, an application is needed that can handle the current problems, namely the cash receipt and disbursement application to help the process of presenting reports briefly and make it easier for employees to enter data, search for data, and computerized income.
Penerapan Akuntansi Pertanggungjawaban sebagai Alat Penilaian Kinerja Manajer Pusat Biaya pada PT. Semen Indonesia Logistik
Authors: Nabilah Nur Fauziah  , Anwar Hariyono
Published: January 2025

PT. Semen Indonesia Logistik, as a logistics service provider company, plays a strategic role in supporting Indonesia's economic dynamics. This research aims to determine the extent to which responsibility accounting is implemented as a tool to assess the performance of cost center managers at PT. Semen Indonesia Logistik in supporting the achievement of company objectives. Responsibility accounting is one of the most important components of overall control in a company. This research uses a qualitative descriptive method with a case study approach. The analysis results show that PT. Semen Indonesia Logistik has implemented responsibility accounting optimally. This can be seen from the responsibility accounting requirements that have been implemented, including the organizational structure that has described the authority and responsibility of each level of manager in the company. The company has carried out budget preparation by classifying controllable and uncontrollable costs, account code classification, and responsibility reports. The implementation of responsibility accounting plays an important role in determining responsibility centers, making it easier for managers to evaluate their performance according to established responsibilities. The performance assessment standard at PT. Semen Indonesia Logistik uses Key Performance Indicators (KPI) that must be achieved within one period.
Adicciones y discapacidad: medidas adoptadas por la legislación para la protección en el ámbito personal y patrimonial
Authors: Ramón Fernández Francisca
Published: January 2025

La adicción a medicamentos, alcohol o drogas puede provocar en la persona una discapacidad. En la actualidad, la legislación se ha orientado a adoptar una serie de medidas de apoyo para proteger a las personas con discapacidad, sea cual sea el motivo que les haya llevado a dicha situación, tanto en el ámbito personal como patrimonial. Ya no se habla de la incapacitación en la norma, y sí de diversas medidas a adoptar tanto en la Ley 41/2003, de 18 de noviembre, de protección patrimonial de las personas con discapacidad y de modificación del Código Civil, de la Ley de Enjuiciamiento Civil y de la Normativa Tributaria con esta finalidad, como en la Ley 8/2021, de 2 de junio, por la que se reforma la legislación civil y procesal para el apoyo a las personas con discapacidad en el ejercicio de su capacidad jurídica. Dentro de estas medidas hay que diferenciar a la persona menor y al mayor de edad. El propósito de este estudio es analizar dichas medidas en relación con la discapacidad y la adicción, bien cuando la adicción determina una situación de discapacidad, como cuando la persona discapacitada tiene una adicción posterior con la finalidad de proteger tanto a la persona como a los bienes.
FETOMATERNAL OUTCOME AMONG PREGNANT WOMEN PRESENTED WITH OBSTETRIC CHOLESTASIS
Authors: REHMAN N , ASLAM S , SIDDIQUE US , JAMIL F , KHTTAB AISA
Published: January 2025

Obstetric cholestasis is a significant condition in pregnancy, associated with adverse fetomaternal outcomes, particularly at term. Timely diagnosis and management are crucial to mitigate complications. Objective: The aim of this study was to evaluate the fetomaternal outcomes among pregnant women diagnosed with obstetric cholestasis at term. Methods: This cross-sectional study was conducted from January 1, 2024, to July 1, 2024, in the Department of Obstetrics and Gynecology. Consecutive non-probability sampling was used to recruit women aged 18-40 years diagnosed with obstetric cholestasis at term. Patients with acute hepatitis, chronic kidney disease, or drug-induced hepatitis were excluded. Demographic data such as age, BMI, educational status, occupation, socioeconomic status, and residence area were recorded. Fetomaternal outcomes, including emergency cesarean section, sleep disturbances, postpartum hemorrhage, low birth weight (<2.5 kg), APGAR score <7, NICU admission, and meconium-stained liquor, were assessed. Results: A total of 120 patients were included in the study. The mean age of participants was 28.56 ± 6.40 years, and the majority were within the 18-30 years age group. Fetomaternal outcomes showed that 35% of the women required an emergency cesarean section. Sleep disturbances were observed in 54.2%, and postpartum hemorrhage occurred in 11.7% of cases. Low birth weight was recorded in 20.8% of neonates, while 10% had an APGAR score <7. NICU admission was required for 23.3% of the neonates, and meconium-stained liquor was present in 35.8% of deliveries. Conclusion: The study demonstrated significant fetomaternal outcomes in obstetric cholestasis, emphasizing the need for early detection and careful management to reduce complications such as higher rates of emergency cesarean sections, sleep disturbances, postpartum hemorrhage, low birth weight, and NICU admissions.
EFFECT OF ASCORBIC ACID IN MITIGATING COPPER STRESS IN PEA (PISUM SATIVUM L.)
Authors: ABBAS T , TASADAQ M , AHMAD W , YOUNAS HS , TARIQ MU , IRFAN M , ALTAF K
Published: January 2025

This study investigated the impact of excessive copper concentrations and varying ascorbic acid levels on the growth and yield of pea seedlings (Pisum sativum L.). Pea plants were subjected to 50 μM copper stress and subsequent foliar spray of control (distilled water), 30 mM, and 60 mM ascorbic acid were applied. 'Orion' pea seeds were sown in pots filled with sand. Hoagland's solution was provided as a nutrient source. After 35 days, 50 μM copper sulfate was applied to the soil as a basal dose. A week later, ascorbic acid at 0, 30, and 60 mM concentrations was applied as a foliar spray. The experiment was conducted in a completely randomized design with six treatments and three replications. Results showed that ascorbic acid significantly improved plant growth as evidenced by increased fresh and dry weight, shoot length, leaf area, and chlorophyll content. The combination of 60 mM ascorbic acid with 50 μM copper resulted in the highest values for most growth parameters, including yield components such as the number of pods and seeds. These findings suggested that ascorbic acid can effectively mitigate the negative effects of copper stress on pea plants, promoting growth, enhancing photosynthetic efficiency, and ultimately leading to increased yield. Copper, an essential micronutrient, can become toxic at high concentrations, while ascorbic acid plays a crucial role in modulating plant growth and stress tolerance.
Impact of Different Concentrations of Aluminum Chloride on Callus Induction and Organogenesis in Date Palm (Phoenix dactylifera L.) cv. "Barhi"
Authors: Zainab Tariq Safi Al Ali  , Majid Abdulhameed Ibrahim  , Khaun Ali Muhsen
Published: January 2025

The present study was conducted in the Plant Tissue Culture Laboratory, Date Palm Research Center, University of Basrah, Basrah, Iraq for the years 2023 and 2024. The investigation aims to test the effect of adding different concentrations of aluminum chloride (0, 15, 30, and 45mg L-1) to the MS medium prepared to induce callus and indirect shoot regeneration of date palm (Phoenix dactylifera L. cv. Barhi)  grown using an in vitro culture technique. The results showed that the aluminum chloride treatment at a concentration of 45mg L-1 significantly outperformed the 15 mg L-1 treatment of aluminum chloride and the control treatment in response to callus induction (%), fresh and dry weight (mg). The control treatment recorded the lowest values in response to callus induction and fresh and dry callus weight. The results indicate that the aluminum chloride treatment at a concentration of 45mg L-1 significantly outperformed the 15mg L-1 treatment of aluminum chloride and the control treatment in response to shoot regeneration, number of shoots per culture, shoot length, and number of leaves per shoot. The control treatment recorded the lowest values in these characteristics.
Strategic Leadership: Navigating dilemmas upon incumbent entry into nascent ecosystems
Authors: Ellis Stephen James
Published: January 2025

This study is composed of three empirical studies, each a single-case qualitative investigation on the incumbent firm Atos. All three studies (Chapters 2-4) focus on the sociopolitical dynamics behind incumbent platform strategy formulation and implementation. Respectively, these chapters: showcase the multi-directional and intertemporal legitimization activities that middle managers must engage in to enact their visions (Chapter 2); analyze the importance of a platform strategy as a signaling tool as well as an innovation mechanism for the incumbent firm (Chapter 3); and theorize on stakeholder-centric challenges that platform leaders may experience when attempting to develop sustainability-related innovation strategies which diverge from their incumbent firms’ traditions.
Practical Applications of Neutrosophic Logic in Enhancing the Accuracy of Economic Forecasting Models and Supporting Decision-Making in Banks
Authors:   Department of Economics, Applied College, Qassim University, Qassim, Saudi Arabia, Khaled Khaled ,   Department of Finance,Faculty of Business, Imam Mohammed Ibn Saud Islamic University, Riyadh, Saudi Arabia,   Department of Finance,Faculty of Business, Imam Mohammed Ibn Saud Islamic University, Riyadh, Saudi Arabia,   Department of Economics, Applied College, King Faisal University, Al-Ahsa, Saudi Arabia, Hussin Hiba Awad Alla Ali , Ali Nadia Bushra Mohammed , Tayfor Abdelsamie Eltayeb
Published: January 2025

Using three machine knowledge models that utilise Neutrosophic Logic (NL)—Linear Regression, Random Forest, and Gradient Increasing—this study studies the possibilities of refining financial result forecast. The cognitive behind this is that NL recovers the prediction power of these models across dissimilar organisations by accounting for the inherent uncertainty, unpredictability, and lack of sureness in financial numbers. In this study, the models' presentation is evaluated using a variety of financial factors, including interest rates and stock prices. F1 score, recall, correctness, and exactness are some of the metrics used by this drive. When likened to other models, NL with Gradient Cumulative consistently outperforms them in terms of correctness and robustness. You might think of Abu Dhabi Islamic Bank and the National Bank of Bahrain as two such examples. Companies like Emirates Islamic Bank reap some benefits from Chance Forest's combination of cheap computation with precision, but only to a lower degree. Complex datasets used by businesses like Al Rajhi Bank are beyond the capabilities of Linear Reversion, even when combined with NL. By proving that cooperative techniques combined with NL positively reduce financial data volatility, our results lay the groundwork for improved financial forecasting and decision-making. The exercise has demonstrated that NL has great potential to enhance financial prediction models, which could have future applications in investment planning and risk organization.
Effectiveness of a commercial LAMP technology-based kit for rapid detection of Bursaphelenchus xylophilus in Pinus pinaster
Authors: Menéndez-Gutiérrez María , Villar Lucía , Díaz Raquel
Published: January 2025

Aim of study: To assess the usefulness of the commercial Loop-Mediated Isothermal Amplification (LAMP) kit for detecting Bursaphelenchus xylophilus (Steiner & Buhrer) Nickle in Pinus pinaster Aiton and Pinus radiata D. Don under field conditions, thus contributing to the advancement of efficient surveillance and management strategies to combat this pathogen.
Material and methods: In three different experiments, the detection rate of the B. xylophilus LAMP kit was compared to the traditional Baermann funnel technique for nematode extraction. Both detection methodologies were applied to detect B. xylophilus from different origins (Spain, Portugal, Asia, and United States) in directly inoculated P. pinaster wood chips or in samples from inoculated P. radiata and P. pinaster seedlings.
Main results: The LAMP kit successfully identified B. xylophilus in samples from all studied origins. We observed a decrease in the detection rate as the number of days since inoculation increased. At 90 days after inoculation (DAI), the detection level in P. pinaster wood chips using the LAMP kit was 18%; whereas in seedlings, no nematodes were detected at 70 DAI with the LAMP kit. However, nematodes were extracted from 83% of the samples using the Baermann funnel technique, although in lower numbers than on other sampling dates.
Research highlights: The commercial LAMP kit is a simple and rapid method for B. xylophilus detection, but it is not fully adapted to the field sampling requirements of the species studied.
Current Landscape and Prospects of CAR-T Cell Therapy in Prostate Cancer: A Clinical Trial Review
Authors: Zhou Jiasheng
Published: January 2025

This review talks about the causes and dangers of prostate cancer. The widespread of prostate cancer and the shortcomings of traditional therapies are discovered, and the principles, significance, and prospects of CAR-T therapy were discussed. Through discussing the significance of CAR-T therapy and the progress of clinical trials. This paper talks about the relevant targets of CAR-T therapy for prostate cancer such as PSMA, PSCA, reviews the purpose, process and results of currently approved clinical trials. This review hopes to find the focus and shortcomings of current CAR-T therapies in the clinical trials and contributes to the development of more efficient CAR-T therapies
The Research Progress of Drugs for Treatment of AlzheimerS Disease
Authors: Zhang Yuchen
Published: January 2025

In this society, Alzheimer's disease represents a significant public health concern. Nevertheless, the market offers only two FDA-approved drugs, which are capable of only partially inhibiting the symptoms. It is imperative that both patients and researchers are made aware of the mechanism by which AD is triggered and the fundamental logic underlying the action of each drug. This should include an understanding of how the drug reacts with the body and the ingredients that it contains. This section primarily discusses the therapeutic options for Alzheimer's disease, encompassing both the drugs and mechanisms that are currently available on the market and those that have not yet been approved but are theoretically feasible. This passage will introduce a number of potential treatments for Alzheimer's disease, including Chinese patent medicine, acetylcholinesterase inhibitors, NMDA receptor antagonists, Aduhelm, Leqembi, anti-amyloid therapies and A immunotherapies. Despite the existence of these treatments for many years, it is still not possible to cure Alzheimer's disease completely or to delay or prevent its progression. This passage aims to provide insights into the future direction of pharmaceutical research and the selection of appropriate medications
Analysis of the Factors Influencing the Calories of Cereals
Authors: Gu Zihui
Published: January 2025

Cereals are a major global source, classified into whole and refined grains. Whole grain cereals provide a higher nutritional value due to the inclusion of the bran, germ, and endosperm, making them a rich source of dietary fiber, vitamins, and minerals. Conversely, refined grains undergo processing that eliminates the bran and germ components, resulting in a loss of valuable nutrients. In recent years, there has been a growing interest in exploring the health benefits of whole grain cereals. Research has established a connection between whole grains consumption and reduced risks of chronic diseases such as heart disease, diabetes, and certain cancers. Additionally, whole grains are recognized for their role in maintaining digestive health and promoting satiety which can aid in weight management. Therefore, this paper aims to investigate how various element present total calorie content using R-studio. The findings reveal that calories serves as the independent variable while protein content, type, sugars and carbohydrates act as independent variables influencing calorie levels accordingly. Cereal type plays a negative role by increasing calories whereas other factors contribute positively positively towards increased caloric intake levels
Research on Automatic Grasping System of Industrial Robot Based on Computer Vision
Authors: Deng Yiqun
Published: January 2025

The first paper focuses on YOLOv5 model optimization for advanced image processing, cu. The second paper explores low-cost machine vision cameras, achieving 97% accuracy in grasp verification. The third paper implements SVM algorithm with ArUco markers for hand-eye calibration. The adjustments made to the connection of sensing and motion system significantly expanded the scope of the detection while maintain the accuracy of grasping.. The fourth and fifth experiments improved the existing models by adding coordinate systems and wrist-mounted cameras separately. By doing so, it is possible to catch clearer and more precise pictures of the target objects. The final two research focus on promoting the automatic aspect of the system. Utilizing two networks and corresponding datasets, for one; employing multiple innovative vision-based techniques, for another. These studies collectively demonstrate the advancement in machine vision-based robotic grasping through various technical approaches, including model optimization, hardware evaluation, and algorithm implementation for improved accuracy and efficiency.
Research on the Application of Flexible Pressure Sensors in Wearable Devices
Authors: Qiao Yuxuan
Published: January 2025

The potential applications of transparent, adaptable electronic devices in the human body are driving up demand for them. For flexible and wearable electronics, such as medical surveillance devices and artificial skin, pressure sensing is mandatory. The flexibility and sensitivity of pressure sensors have advanced recently owing to developments in material and device structure. Moreover, their low manufacturing costs enable widespread implementation, leading to promising application prospects. The sensors utilize different materials and structures, including capacitive pressure sensors with ionically charged CFMs, magnetic particle-infused carbon sponges, CNT-PDMS composites, and MoSe2/MWNT combinations. These sensors offer advantages such as high sensitivity, wide pressure-detecting ranges, optical transparency, and energy efficiency. They can detect both large and subtle human movements, from walking and finger bending to breathing and eye blinking. The fabrication methods range from simple and cost-effective processes to more complex techniques like photolithography. Many of the sensors incorporate carbon nanotubes (CNTs) in various forms, exploiting their excellent electrical properties. The review highlights the potential of these sensors for healthcare monitoring, clinical diagnosis, and integration into wearable electronics, emphasizing their flexibility, biocompatibility, and ability to provide real-time, non-invasive measurements of physiological signals. Moreover, their low manufacturing costs enable widespread implementation, leading to promising application prospects.
Autonomous Driving Control Strategy Based on Deep Reinforcement Learning
Authors: Yang Liangjun
Published: January 2025

This paper discusses an autonomous driving control strategy based on Deep Reinforcement Learning (DRL), which aims to improve the decision-making ability of autonomous driving system in complex traffic environments. Deep reinforcement learning has a wide range of applications in many fields, such as robotics and medicine. Autonomous driving has emerged as a significant research focus in recent years. By combining deep learning and reinforcement learning, the model is able to autonomously learn and optimize driving behavior under dynamically changing road conditions. The DRL-based control strategy performs well in vehicle obstacle avoidance, pedestrian recognition, and traffic rule compliance in the face of complex environments such as city streets, intersections, and congested road sections, significantly improving the safety and efficiency of autonomous driving. This article will first introduce deep reinforcement learning. Then, the autonomous driving control strategy based on deep reinforcement learning is introduced. This research provides valuable insights for developing and implementing DRL-based autonomous driving systems.
Research on Low-Power Design Methods for Integrated Circuits
Authors: Wang Shoutao
Published: January 2025

The development of the integrated circuit industry has led to an increase in both the operating frequency and integration density of CMOS circuits, which has also resulted in a rising power density. To address the various adverse effects of increased power consumption on chip design, low-power design has become an essential aspect of chip development. This paper begins by examining the origins of power consumption and, based on this analysis, introduces low-power design techniques at the system architecture level, RTL level, as well as clock gating, multi-threshold voltage technology, and power gating techniques. These approaches allow designers to choose the optimal combination of power-saving techniques according to specific design needs, achieving lower power consumption without compromising performance.
Computational Simulations of Metal-Organic Framework Structures Based on Second Building Units
Authors: Jin Yilin
Published: January 2025

Metal-organic frameworks (MOFs) are crystalline porous materials composed of metal clusters and organic linkers with tunable structures and large surface areas, making them ideal for gas storage, separation, and catalytic applications. The development of new MOFs and the screening of MOFs after synthesis are usually experimental, but the cost and time required for experiments are very large. Interestingly, computational simulations have become a powerful tool to accelerate the discovery of new MOFs structures. This study focuses on the computational design of MOFs based on secondary building units (SBUs) and explores the effects of different linkers on their geometry and properties. Using techniques such as density functional theory (DFT) and machine learning (ML), MOFs can be screened for great gas adsorption and storage properties. The results show that computational methods have the potential to predict and optimize MOFs structures, but they are still limited in accurately simulating dynamic environmental conditions and complex chemical reactions. These findings help advance the design of MOFs with tailored properties for specific industrial applications.
A Study on EFL Vocabulary Teaching for Non-English Major College Students in China Based on Multimodal Theory
Authors: Zhou Xuanxuan , Sulaiman Nur Ainil , Ismail Hanita Hanim
Published: January 2025

In the era of global diversification and technological advancement, the vocabulary teaching of teaching English as a Foreign Language (EFL) faces new challenges and opportunities. Multimodal theory-based teaching has gained significant attention in academic research. This study addresses the challenges in EFL vocabulary acquisition among non-English major students by employing the Explanatory Sequential Design (ESD). Initially, this study conducted a quantitative semi-structured questionnaire involving 78 non-English major college students in China. It identified key vocabulary learning issues, including monotonous vocabulary presentation content, limited vocabulary teaching methods and tedious vocabulary tasks. To address these challenges, this research implemented a research practice at Wenzhou Business College (WZBC) for one semester with 20 non-English major students, focusing on pre-class, in-class, and post-class stages. This study collected data to evaluate the effectiveness of the intervention and conducted a follow-up interview with 5 students to gain deeper insights. This study shows that applying multimodal theory in EFL vocabulary teaching enhances vocabulary acquisition by engaging students with varied content, interactive methods, and customised tasks that build confidence, thereby boosting interest and participation in vocabulary learning. These findings offer valuable insights for advancing EFL educational practices.
Overview of Available Treatments and Their Limitations for Hypertrophic Facet Joints—A Systematic Review of the Literature
Authors: Hawkins Noel , García Allison , López-Candelas Fernando , Aguirre David Salinas , Trujillo Onerys Sierra , Llerenas King López Daniela , Álvarez-Palazuelos Lucia Elizabeth , Ruiz-Ramírez Andrea Virginia
Published: January 2025

Background:

Physicians worldwide face the challenging task of improving patient satisfaction by reducing pain in injured patients. Currently, available therapeutic approaches provide only short-term relief of symptoms without addressing long-term satisfaction. This has led to exploring regenerative treatment options that can deliver better outcomes. One such promising option is platelet-rich plasma (PRP) injections, which are gaining popularity as an alternative to standard steroid injections.

Objectives:

This study examines the therapeutic effects of PRP injections in adult patients with stress or traumatic injuries.

Methods:

The systematic literature review yielded 60,301 articles, books, and websites verified and removed from the final project. The final studies used in the report comprised randomized trials, observational studies, and case reports on injecting biologics into the epidural space, facet joints, or sacroiliac joints. In total, 15 reviews and 13 studies were included in this review.

Results:

In the Wu et al study, 46 participants were randomly divided into group A (0.5 mL PRP injection) and group B (1.5 mL methylprednisolone injection). Although group B initially showed a notable pain reduction at one week, it diminished over 6 months, with group A consistently improving, reaching an 80.96% success rate and higher patient satisfaction. In the study by Singla et al comparing PRP (group P) and corticosteroid (group S) in 40 participants, PRP demonstrated a markedly greater reduction in VAS Scale at 6 weeks and 3 months, with a 90% effectiveness compared with 75% for steroids.

Conclusion:

PRP injections offer greater pain alleviation, disability reduction, and overall patient satisfaction improvements due to their effect on the immune response to promote the growth and proliferation of damaged tissue. It has also been shown to offer a safer alternative that carries fewer risks than that of transforaminal steroid injections due to promising clinical trials and scientific investigation outcomes. Several of the steroid injection studies proved to have mixed results and efficacy because patients reporting having similar pain relief with placebo groups that used saline injections. Further studies will be needed to evaluate PRP's long-term efficacy and cost-effectiveness for practical patient use in the future.
The Long-Term Relationship between Insurance Customers and Agents: The Importance of Full Disclosure for Optimal Coverage
Authors: Elomari Raed
Published: January 2025

This review article explores the critical role of full disclosure in fostering a long-term relationship between insurance customers and agents. This examines the functional responsibilities of insuring agents, the importance of full disclosure, strategies for building lasting relationships, and how full disclosure leads to optimal coverage. This also addresses challenges and barriers to full disclosure and discusses future trends in the insurance industry. For the execution of this review, the recent research and reviews/articles published are based on the Long-Term Relationship Between Insurance Customers and Agents: The Importance of Full Disclosure for Optimal Coverage. In this given review, data was gathered by the applicability of several search engines Studies or journal articles were selected through inclusion-exclusion criteria. The studies selected from the years ranging between 2019 to 2024 by using different keywords like “Insurance customers,” “agents,” “full disclosure,” “optimal coverage,” After searching relevant papers on different search engines including Google Scholar, to apply different keywords like “Insurance customers,” “agents,” “full disclosure,” and “optimal coverage,”, the researcher initially found 2200 papers for publication relevant to. After filtration of studies, the researcher narrowed down to 400 articles related to the Importance of Full Disclosure for Optimal Coverage After further screening and use of the most relevant variables of the study, the articles were reduced to 150. Customers have become more informed and technologically practical, and their expectations for transparency promote a personalised service in the insurance industry that has risen. Modern customers demand instant accessibility to information, clarity in communication, and tailored insurance solutions that meet specific needs.
Documentary Evidence for the Activities of the Bulgarian Revival Municipality in Karlovo until the Liberation
Authors:   St. Cyril and St. Methodius University of Veliko Tarnovo, Bulgaria, Deyanova Maria
Published: January 2025

The Bulgarian municipality in Karlovo, established during the period of the National Revival, in the epoch of Tanzimat, became an institution of local self-government, protecting the interests and prosperity of the community. The municipality worked for the development of education in the Revival town. In addition to the implementation of fiscal and intermediary functions it organized the construction of public buildings and rose for the support of public institutions like churches, schools, etc. From the available historical documents, it is clear that the Karlovo municipality actively participated in the movement for independent Bulgarian church hierarchy and national emancipation in the Plovdiv diocese.
New Challenges for the Development of Beekeeping in Bulgaria – Trends and Problems
Authors:   St. Cyril and St. Methodius University of Veliko Tarnovo, Bulgaria, Yordanova Polya
Published: January 2025

Bulgarian beekeeping is in a serious crisis in the last years. More than one is the reason for the state of the sector, but according to beekeepers it has reached its bottom and is in a dire need of support – not only financially, but also by a comprehensive government policy and protection, which has lacked recently according to the beekeepers. Many of them give up their activities and sell their apiaries – hives and bee families, because they see no other way out. Others who produce larger quantities of honey see serious problems in its sale. Among the reasons that beekeepers indicate are mass poisonings of bees as a result of agricultural activity.
The Killing of Milthocytes in Historico-Anthropological Perspective
Authors:   St. Cyril and St. Methodius University of Veliko Tarnovo, Bulgaria, Nikolov Nikolay
Published: January 2025

Milthocytes was a leader of two Thracian revolts – one against the Odrysian ruler Kotis and another against Kotis’ son and successor to the throne, Kersebleptes. Because of his role in the second revolt, Milthocytes was executed, and according to the ancient authors, the rebel’s death came through a strange way of killing. The description of his specific execution reminds us of the bloodless forms of killing, practiced by the early societies in the Americas, Asia, Africa, and Australia, studied by sociocultural anthropologists. Thus, by adopting the historico-anthropological approach and, in particular, the comparative method of anthropology, this paper aims to explain the meaning of Milthocytes’ execution.
The Time of the Democratic Alliance and Its Mayors in Haskovo (1923–1931)
Authors:   St. Cyril and St. Methodius University of Veliko Tarnovo, Bulgaria, Uzunova Krasimira
Published: January 2025

The government of the Democratic Alliance in the post-war years was a period of economic stabilization, strengthening of local governing institutions and strong social politicization. In this dynamic and difficult time, the mayors of Haskovo, persons with good education and high public culture, showed modern thinking and approach to the city management, as a result of which Haskovo became a modern European city.
Information of the Commandant of the Yambol Military Prison about the Prisoners, the Administration and the Office of the Prison within the Period 1938–1940
Authors:   St. Cyril and St. Methodius University of Veliko Tarnovo, Bulgaria, Ivanov Stanislav
Published: January 2025

In this publication, we will present information and statistical data on the condition and status of prisoners in the Yambol Military Prison, orders for career development of employees and other reports in the period from 1938 to 1940, stored in Fund 16 of the State Military History Archive in the town of Veliko Tarnovo. In the course of our study we will focus on the data about the age and social composition of the prisoners and about the specific character of their sentences. Our main purpose is to present new touches from the history of the Yambol garrison (in the interwar period) and in particular of the Yambol Military Prison. After abolition of the military restrictions on Bulgaria in the summer of 1938, imposed by the victors of the First World War, the Bulgarian authorities proceeded to quickly restore the combat effectivеness of the Bulgarian Army, respectively its transition from a voluntary into conscript army.
Dobri Chintulov and the Bulgarian National Revival
Authors:   St. Cyril and St. Methodius University of Veliko Tarnovo, Bulgaria, Tihova Tanya
Published: January 2025

The article explores the life path, creative work and public activity of Dobri Chintulov. The author comes to the conclusion that it is necessary to continue scholarly research on the life and activities of the poet, composer, pedagogue and public figure Dobri Chintulov, because the memory of his personality should not fade in the minds of the Bulgarians.
Research on the Defect Detection System of Solar Cell Sheets based on the YOLOv9 Model
Authors: Zhang Zongyi , Wan Guoliang
Published: January 2025

A multi-station visual detection system is proposed to address the challenge of detecting various typical defects in solar cell sheets. To improve the detection accuracy of solar cell sheet defects, optimization of the YOLOv9 object detection model is explored. The introduction of the CBAM attention mechanism into the YOLOv9 model's backbone network enhances its ability to extract typical defects. The EIOU loss function replaces the original CIOU loss function, improving both the accuracy of the detection frame and the detection speed. Dynamic Snake Convolution (DSConv) is incorporated into the model to improve its recognition capability for small target defects. The effectiveness of the multi-station visual detection system and the superiority of the optimized model are validated through comprehensive stepwise and comparative experiments across different models.