bluuebunny/crossref_metadata_2025 huggingface dataset:
BACTERIAL COMMUNITY SUCCESSION AND INFLUENCING FACTORS OF IMPERATA CYLINDRICA LITTER DECOMPOSITION IN A DEGRADED COPPER TAILINGS DAM OF CHINA
Authors: Jia Tong , Liang Xiaoxia , Guo Tingyan , Chai Baofeng
Published: September 2021

Litter decomposition is a critical component of the ecological
nutritional transformation process. It is particularly important to
investigate characteristics and interactions of bacterial communities in
litter decomposition in heavy metal polluted degrade areas, which will
help clarify driving mechanisms of organic matter and nutrient cycling
in mining areas that harbor contaminated soil. Imperata cylindrical was
the dominant plant species in the degrade area investigated; thus, we
selected this species as research object. Here we explore bacterial
community characteristics and key microbial groups as well as driving
factors of litter decomposition using in-situ litter decomposition
experiments. The nutrient content of I. cylindrica decreased, while the
litter pH status increased as decomposition progressed in one of the
three sub-dams investigated (i.e., S516). Proteobacteria and
Actinobacteriota were the dominant bacterial phyla during the different
litter decomposition stages. Moreover, the role of Friedmanniella was
critical in sustaining both structure and function of the bacterial
community during the early decomposition stage. Quadrisphaera became the
dominant species as litter decomposition progressed. Litter properties
and enzyme activities both had significant effects on litter bacterial
community characteristics, whose driving factors varied during different
restoration stages. The bacterial community dynamics of litter were
affected primarily by litter properties during the decomposition
process. Furthermore, the most crucial factors that impacted bacterial
litter structure were pH and copper content. Findings will help to
deepen our understanding of litter decomposition mechanisms in degraded
ecosystems, while also providing a scientific basis for improving
effectiveness of material circulation and nutrient transformation in
degrade ecosystems.
Reviewing short cervix in singleton pregnancies: a multicentric prospective cohort study in the Brazilian population
Authors: Silva Thaís , Pinheiro Anderson , Cecatti Jose , Mol Ben , Costa Fabrício Da Silva , Franca Marcelo , Souza Renato , Devlieger Roland , Jr Renato Passini , Pacagnella Rodolfo
Published: September 2021

Objective: To identify the association between cervical length (CL) and
gestational age at birth. Design: Prospective cohort study. Setting:
Seventeen Brazilian reference hospitals. Population: A cohort of 3139
asymptomatic singleton pregnant women who participated in the screening
phase of a Brazilian multicenter randomized controlled trial (P5 trial).
Methods: Transvaginal ultrasound (TVU) to measure CL was performed from
18 to 22+6 weeks. Women with CL ≤ 30 mm received vaginal progesterone
(200 mg/day) until 36 weeks’ gestation. Main Outcome Measures: Area
under receive operating characteristic curve (AUC), sensitivity,
specificity, Kaplan-Meier curves for preterm birth (PTB), number needed
to screen (NNS). Results: CL ≤25mm was associated with extremely severe,
severe, moderate and late PTB, whereas a CL 25–30mm was directly
associated with late sPTB. The AUC to predict sPTB<28 weeks
was 0.82 and for sPTB<34 weeks was 0.67. Almost half of the
sPTB occurred in nulliparous women and CL ≤30mm was associated with sPTB
<37 weeks (OR = 7.84; 95%CI = 5.5–11.1). The NNS to detect
one sPTB <34 weeks in women with CL ≤25mm is 121 and 248
screening tests are necessary to prevent one sPTB <34 weeks
using vaginal progesterone prophylaxis. Conclusions: CL measured by TVU
is associated with sPTB <34 weeks. Women with CL ≤30mm are at
increased risk for late sPTB. Funding: Bill & Melinda Gates Foundation
[OPP1107597], the Brazilian Ministry of Health, and the Brazilian
National Council for Scientific and Technological Development (CNPq)
[401615/20138]. Keywords: cervical length; number needed to screen;
preterm birth; short cervix.
Left atrial strain and derived indexes in diagnosing of heart failure with preserved ejection fraction
Authors: Ma Changsheng , Liao Yuping , Fan Jia Li , Zhao Xin , Su Bo , Zhou BingYuan
Published: September 2021

Objectives. We sought to evaluate the ability of left atrial strain and
derived index to discriminate patients with HFpEF from individuals with
risk factors of HFpEF. Methods and results. A total of n=389 patients
with risk factors for HFpEF finally was prospectively enrolled into the
study, 51 of them were diagnosed with HFpEF by ESC diagnostic criteria.
55 patients were undergone left ventricular catheterization, 35 of them
with LVEDP elevated. Left atrial strain was measured in all patients.
Compared patients without HFpEF, LASr and LASr/(E/e’) was lower in
HFpEF; E/LASr, LAVi/LASr and LVMI/LASrwas higher in patients with HFpEF.
After adjusted for hypertension, diabetes, chronic kidney disease, LVEF
and NT-proBNP, multivariate logistic regression analyses showed that
LASr and derived indexes(E/LASr, LASr/(E/e’), LAVi/LASr and LVMI/LASr)
were still the predictors of HFpEF in their respective models. LASr had
good diagnostic accuracy for HFpEF. Of the left atrial strain derived
parameters, LVMI/LASr was the best discriminatory ability for HFpEF (AUC
0.796, cutoff value 5.2, specificity 82%, sensitivity 73%). LASr,
LASr/(E/e’), LAVi/LASr and LVMI/LASr with higher AUC was superior to
conventional echocardiographic measures of diagnosing HFpEF. LASr and
derived indexes were incorporated into the ESC diagnostic criteria,
LASr-HFA-PEF score system (AUC=0.804) had a higher detection rate of
LVEDP≥16mmHg than the HFA-PEF score system (AUC=0.781). Conclusion. LASr
and derived indexes with good accuracy beyond conventional
echocardiographic parameters discriminate HFpEF from patients with risk
factors of HFpEF. LASr and derived indexes incorporated into the ESC
diagnostic criteria will improve the diagnostic efficiency.
Optimization of the “in-silico” mate-pair method improved contiguity and accuracy of genome assembly
Authors: Zhou Tao , Lu Liang , Li Chenhong
Published: September 2021

A combination of next-generation sequencing technologies and mate-pair
libraries of large insert sizes is used as a standard method to generate
genome assemblies with high contiguity. The third-generation sequencing
techniques also are used to improve the quality of assembled genomes.
However, both mate-pair libraries and the third-generation libraries
require high-molecular-weight DNA, making the use of these libraries
inappropriate for samples with only degraded DNA. An in silico method
that generates mate-pair libraries using a reference genome was devised
for the task of assembling target genomes. Although the contiguity and
completeness of assembled genomes were significantly improved by this
method, a high level of errors manifested in the assembly, further to
which the methods for using reference genomes were not optimized. Here,
we tested different strategies for using reference genomes to generate
in silico mate-pairs. The results showed that using a closely related
reference genome from the same genus was more effective than using
divergent references. Conservation of in silico mate-pairs by comparing
two references and using those to guide genome assembly reduced the
number of misassemblies (18.6% – 46.1%) and increased the contiguity
of assembled genomes (9.7% – 70.7%), while maintaining gene
completeness at a level that was either similar or marginally lower than
that obtained via the current method. Finally, we compared the optimized
method with another reference-guided assembler, RaGOO. We found that
RaGOO produced longer scaffolds (17.8 Mbp vs 3.0 Mbp), but resulted in a
much higher misassembly rate (85.68%) than our optimized in silico
mate-pair method.
ABA-induced cytoplasmic translocation of COP1 enhances ROS accumulation through the HY5-ABI5 pathway to modulate seed germination
Authors: Chen Qing-Bin , Wang Wenjing , Zhang Yue , Zhan Qidi , Liu Kang , Botella Jose Ramon (Jimmy) , Bai Ling , Song Chunpeng
Published: September 2021

Seed germination is a physiological process regulated by multiple
factors. Abscisic acid (ABA) can inhibit seed germination to improve
seedling survival under conditions of abiotic stress, and this process
is often regulated by light signals. Constitutive Photomorphogenic 1
(COP1) is an upstream core repressor of light signals, and is involved
in several ABA responses. Here, we demonstrate that COP1 is a negative
regulator of the ABA-mediated inhibition of seed germination. Disruption
of COP1 enhanced Arabidopsis seed sensitivity to ABA and
increased ROS levels. In seeds, ABA induced the translocation of COP1 to
the cytoplasm, resulting in enhanced ABA-induced ROS levels. Genetic
evidence indicated that HY5 and ABI5 act downstream of COP1 in the
ABA-mediated inhibition of seed germination. ABA-induced COP1
cytoplasmic localization increased HY5 and ABI5 protein levels in the
nucleus, leading to increased expression of ABI5 target genes and ROS
levels in seeds. Together, our results reveal that ABA-induced
cytoplasmic translocation of COP1 activates the HY5-ABI5 pathway to
promote the expression of ABA-responsive genes and the accumulation of
ROS during ABA-mediated inhibition of seed germination. These findings
enhance the role of COP1 in the ABA signal transduction pathway.
Plastic responses of survival and fertility following heat stress in pupal and adult Drosophila virilis
Authors: Walsh Benjamin , Parratt Steven , Mannion Natasha , Snook Rhonda , Bretman Amanda , Price Tom
Published: September 2021

The impact of rising global temperatures on survival and reproduction is
putting many species at risk of extinction. In particular, it has
recently been shown that thermal effects on reproduction, especially
limits to male fertility, can underpin species distributions in insects.
However, the physiological factors influencing fertility at high
temperatures are poorly understood. Key factors that affect somatic
thermal tolerance such as hardening, the ability to phenotypically
increase thermal tolerance after a mild heat shock, and the differential
impact of temperature on different life stages, are largely unexplored
for thermal fertility tolerance. Here, we examine the impact of high
temperatures on male fertility in the cosmopolitan fruit fly Drosophila
virilis. We first determined whether temperature stress at either the
pupal or adult life-history stage impacts fertility. We then tested the
capacity for heat-hardening to mitigate heat-induced sterility. We found
that thermal stress reduces fertility in different ways in pupae and
adults. Pupal heat stress delays sexual maturity, whereas males heated
as adults can reproduce initially following heat stress, but lose the
ability to produce offspring. We also found evidence that while
heat-hardening in D. virilis can improve high temperature survival,
there is no significant protective impact of this same hardening
treatment on fertility. These results suggest that males may be unable
to prevent the costs of high temperature stress on fertility through
heat-hardening which limits a species’ ability to quickly and
effectively reduce fertility loss in the face of short-term high
temperature events.
Young Cystic Fibrosis Lung Transplant Recipients: Predisposing Factors for End-stage Disease
Authors: Mallory George , Melicoff Ernestina , Ruiz Fadel , Hosek Kathleen
Published: September 2021

Background: The largest age group among children and adolescents
referred for lung transplantation for cystic fibrosis (CF) have been
those who in the pubertal or post pubertal age range. However, over 100
younger patients with CF have undergone lung transplantation over the
last three decades in the USA. Methods: We performed a retrospective
review of our experience with 18 children with CF who underwent lung
transplantation in our center before the age of 11 years. Results:
Notable findings were a high prevalence of methicillin-resistant
Staphylococcus aureus, a high prevalence of diabetes mellitus and an
impressive prevalence of consolidated lobar or whole lung disease.
Post-transplant outcomes, however, were comparable to those older than
10 years of age in our center. Conclusions: In an era of increasingly
effective medications modifying the natural history of CF,
identification of risk factors for early severe lung disease in CF
remains relevant and potentially more important for effective
intervention in order to extend life.
Fetal cardiac rhabdomyoma as sonographic sign of tuberous sclerosis complex - a diagnosis not to be missed.
Authors: Borza Dan Boitor , Stanila Roxana Popa , Zaharie Gabriela , Hasmasanu Monica , Muresan Daniel
Published: September 2021

Fetal cardiac rhabdomyoma should trigger the awareness of potential
coexisting tuberous sclerosis complex that can lead to a poor
neurological outcome. This condition is not only uncommon but can be
easily unrecognized prenatally in the absence of a meticulous
neurosonogram and MRI. We emphasize that careful consideration of all
prenatal facilities is needed to confirm the diagnosis of tuberous
sclerosis complex as early as possible during pregnancy. Key words:
cardiac rhabdomyoma; tuberous sclerosis; prenatal diagnosis
Levoatrial Cardinal Vein: In two siblings with normal heart morphology
Authors: Şimşek Ayşe , Demircan Tulay , Sarioğlu Fatma , Bağlı Sedat , Gerçeker Engin , Yıldız Kaan , karadeniz cem , Narin Nazmi
Published: September 2021

Levoatrial cardinal vein (LACV) is anomalous connection between the left
atrium or pulmonary veins and any systemic vein which is derived from
cardinal venous system. Presence of the levoatrial cardinal vein without
a cardiac anomaly is a very rare congenital anomaly of the systemic
venous return. In the literature, no LACV anomaly was found in two
siblings who were asymptomatic and did not have an additional cardiac
anomaly. Therefore, we present two cases ( two siblings ) the symptoms,
diagnosis (the echocardiographic finding, computed tomography (CT) and
aniographic images ) and treatment modalities of isolated levoatrial
cardinal vein.
Functional and Microstructural Characterisation of Bambara Groundnut (Vigna Subterranea) Starch as Affected by Varying Degrees of Succinylation
Authors: LA Gibson
Published: September 2021

Bambara groundnut (Vigna subterranea) is an under-exploited pulse rich in starch. Scientific data about the impact of varying degrees of succinylation on its starch content are sparse. Amidst the rising demand for such modified starch variants, bridging this information gap is necessary. Isolated starch from Bambara groundnut seeds was succinylated (2-14g succinic anhydride /100g starch extracted) and thereafter the degree of succinylation was evaluated. Physicochemical, functional, and microstructural characteristics of native and succinylated variants of the Bambara starch (SBS) were investigated using established procedures. Amylose content increased marginally (av.17%) among some samples. Water and oil absorption capacities peaked at 2.498 and 0.7185g /g of starch respectively. Pasting viscosities (5682-7025.5cP) increased irrespective of the order of substitution. X-ray diffract grams indicated an increase in crystallinity (A-type) with a strong peak at approximately 23o (2ϴ). This was however lost at higher treatment levels. FTIR spectra of the starches reflected a typical absorption band of a starch backbone. Scanning electron micrographs of succinylated starches were generally oval, exhibiting surface cracks sizes (13.55-44.25µm). Succinylated Bambara groundnut starches at low treatment levels (2-4%) may prove valuable in soups and gravies requiring a high viscosity, stability, and clarity. At higher treatment levels, non-food applications may just be the right outlet.
Viscosity Measurement of Olive Oil under Pressure
Authors: LT Pawlicki
Published: September 2021

This article presents changes in the viscosity of olive oil during compression. The test was carried out indirectly by measuring the dependence of the resonance frequency of the piezoelectric immersed in olive oil on pressure. For this purpose, for successive pressures, the resonance curves were read and the values of the characteristic frequencies were determined. Viscosity changes were analysed and related to the compression and crystallization taking place in the tested substance. During this research, a phase transition from the liquid phase to the alpha crystalline phase was detected, during which the resonant frequency of the tested piezoelectric reached a minimum and the viscosity related to this frequency reached a maximum. The measurement method developed in this paper can be used to detect the phase transitions of oils subjected to pressure. This may find application in the oil production and high-pressure food preservation industries for which this knowledge is essential for the safe and trouble-free use of their machines.
Effect of Laser Activated Sodium Hypochlorite on Sealing Ability of Two Endodontic Sealers Using Stereomicroscope-An In vitro Study
Authors: Govula Kiranmayi
Published: September 2021

Introduction: The combination of various irrigants, irrigation techniques along with root canal sealers helps in achieving a three-dimensional seal in root canals, which is of clinical relevance. The present in-vitro study aims to assess and compare the efficacy of laser-activated NaOCl on the sealing ability of two endodontic sealers. Materials and Methods: Forty extracted human single-rooted permanent teeth were collected and decoronated 12 mm from their apices. Instrumentation did with an 11 mm working length using Rotary Pro taper files to F3. All the teeth grouped into four (n= 10) based on irrigation protocol and sealer used as follows: Group A1 – Laser activated NaOCl + AH Plus Group A2 – Laser activated NaOCl +nano seal, Group B1 – NaOCl + AH Plus, Group B2 – NaOCl + nano seal. The lateral condensation technique did obturation. Roots stored in freshly prepared 1% methylene blue for 72 hours. The roots were split longitudinally along the long axis using a diamond disc underwater coolant, and markings made at 2, 4, and 6 mm from the apex. The depth of dye penetration and microleakage examined under a stereomicroscope (Magnus) at 30× magnification. Results: Statistical analysis carried out by using the software, statistical package for social sciences [SPSS]. Results represented in the form of minimum, mean, and standard deviation. Conclusion: The laser-activated NaOCl group exhibited better sealing ability than the control group. Among the two sealers, the Bio root RCS sealer showed less leakage & better sealing ability than AH plus Clinical Significance: Increasing the temperature of low concentration sodium hypochlorite solution by the action of the diode laser, not only enhances its immediate tissue dissolution capacity but also increased the dentin permeability by removing the smear layer. Further leading to better adhesion between the root canal sealer and the gutta-percha with the radicular dentin.
What is Behind the High Dental Costs in the U.S.
Authors: Yanushevsky Rafael
Published: September 2021

Healthcare is among the most important issues for Americans since the U.S. health care system is the most expensive in the world. Analyzing the U.S. rising cost of health care in the 21 century it is impossible not to see that the increase of dental prices exceeds significantly the growth of prices for many other medical services. Regular preventive dental care is essential for good oral health, but many persons don’t get the care they need. More people are unable to afford dental care than other types of health care. Such situation with dental health is inadmissible.
A Rare Compound Odontoma in Mandibular Midline Region: Case Report and Literature Review
Authors: Puranik Chaitanya
Published: September 2021

Background: Odontomas are the most common odontogenic tumors of the oral cavity. Although compound odontomas are common in the pediatric population, they are rare in the mandibular midline region during the primary dentition stage. Case Description: This article provides a rare case-report and literature review of a compound odontoma in the mandibular midline region during the primary dentition stage. A routine occlusal radiograph in an asymptomatic six-year-old patient demonstrated mixed, radiolucent-radiodense lesion apical to #N-#P (mandibular primary incisors) with intact lamina dura. Minor expansion and thinning of labial and lingual cortices were noted on cone beam computed tomographic (CBCT) images. This report discusses surgical management, histopathologic diagnosis, and 36-month clinical-radiographic follow-up of our case. Practical Implications: Compound odontomas are highly rare during the primary dentition stage in the mandibular midline (0.3%). Routine radiographs are vital for a timely diagnosis and treatment of these pathologies to prevent future orthodontic complications.
Refractory Thyroid Carcinomas: Experience of the Medical Oncology Department of Hassan II Hospital in Fez, Morocco
Authors: Nouiakh Lamyae , Karima Oualla  , Ouahbi Hajar , Berrad Soumia , Erraichi Hayat , Amaadour Lamiae , Zineb Benbrahim  , Arifi Samia , Meryem boubou  , Nawfel Mellas
Published: September 2021

Background: Refractory thyroid carcinomas are rare. The prognosis of these carcinomas depends on several factors including the histological type and the evolutionary stage. Aim: Determine the epidemiological, pathological and prognostic characteristics of refractory thyroid carcinomas and to focus on the therapeutic modalities used for the treatment of these cancers. Methods: Our work is a retrospective descriptive study on 28 cases collected in the medical oncology department of Hassan II hospital in Fez over a period of 7 years, from January 2012 to January 2019. The statistical analysis of the results was done by SPSS version 23. Survival was calculated by the Kaplan-Meier method. Results: The average age was 57.3 years, with a sex ratio F/M of 1.3. Thyroid nodule and multi-hetero nodular goiter were present in 32.1% and 28.5% of cases, respectively. The most common carcinoma was the papillary (36%) followed by the vesicular (25%), the anaplastic (25%) and the medullary (14%). The first line treatment was based on SORAFENIB (administered to 40% of patients) and on conventional chemotherapy (60%). After an average number of 4 courses, the objective response rate was 47%. The median of progression-free survival was 15 months and that of overall survival was 25 months. Conclusion: Overall, refractory thyroid cancers are rare. Systemic treatments have evolved considerably in recent years with the development of targeted therapies, pending the advent of immunotherapy that could improve the prognosis of patients with these cancers, particularly those with anaplastic carcinoma.
Rapid and Elevated Tumor Responses to Wekley Paclitaxel for AIDS-Related Kaposi Sarcoma
Authors: Berrad S. , Oualla K. , Lokonga V. W. , Nouiakh L. , H. Erraichi  , L. Amaadour  , Z. Benbrahim  , S. Arifi  , N. Mellas
Published: September 2021

Kaposi sarcoma is a rare condition, it is an incurable disease with a poor prognosis, the treatment of this pathology is variable including surgery, Radiotherapy, chemotherapy and antiviral treatments. A number of drugs approved for the treatment of KS associated with AIDS, in particular the pegylated liposomal doxorubicin (DLP) which is currently the standard, Paclitaxel, have also shown efficacy against advanced SK. We report a case of a patient with kaposi's sarcoma associated with HIV metastatic in the lung, liver and lymph nodes and who presented an almost complete response after 4 months of chemotherapy with weekly Paclitaxel at a dose of 100 mg in our department of medical oncology at CHU Hassan II in Fez. Of interest is the complete response to paclitaxel treatment in a patient followed for metastatic kaposi sarcoma.
Dental Implants: Prevalence, Association with Periodontal Diseases and Awareness of Oral Hygiene among Dental Implant Patients in Saudi Arabia: A Cross-Sectional Study
Authors: Amal Abushal  , Malak Alqudsi  , Nujood Alahmadi  , Mohammed Almalsi  , Haifa Alharbi  , Eman Anaim  , Manal Murad  , Abousada Huda
Published: September 2021

Periodontal disease is a broad spectrum that involves different entities and severity levels of the disease. Dental implants, just like normal teeth, can be affected by periodontal disease. This descriptive questionnaire-based study provides a brief shot on the most prevalent periodontal diseases associated with dental implants, associated risk factors, and levels of understanding and awareness about oral hygiene in the Saudi population. Results concluded that 10.5% of population have dental implants. 28.5% the sample confirmed that they have some sort of periodontal disease. Most prevalent symptoms among patients with dental implants are in order: periodontal pockets, redness and blood spitting after tooth brushing, and finally gingival recession. Most associated co-morbidities are cardiovascular disease and diabetes mellitus. Regarding oral hygiene, through assessing two oral health concepts: twice daily tooth brushing, and balanced diet, it is found that more than half of the sample (51.3%) apply these two concepts in their life, while the rest of the sample misses one or both of these two concepts. Focus should be directed toward raising the public awareness about periodontal disease and its symptoms, especially in cases of dental implants, and raising understanding and awareness about different oral health concepts.
Awareness of Smoking among Medical Staff in KSA
Authors: Manal Abdulaziz Murad  , Hoda Jehad Abousada  , Raghad Khalid Aljuaid  , Amal Saud Almaqati  , Rawan Saleh Alotibi  , Anas Ali Alzahrnai  , Matuq Abdulrahman M Zamzama  , Jabr Nahar Bin Jabr Alsulami  , Sarah A. Alghabban  , Amirah Saad Algethami  , Amal Mihmas Alosaimi
Published: September 2021

Among most medical staff, Smoking is very common and, in this research, we aim To Determine awareness of smoking in medical staff, smoking differences between gender and nationality in KSA. Then we overviewed the rates of smoking in different age groups in the general population. We want also to know the connection of this awareness to smoking or quitting, which may cause future plans that provide for the shedding of light on psychological treatment and mental persuasion to help quit smoking.
These study participants were Medical workers from Saudi Arabia and the results may not be applied to different sittings due to differences in facilities and work conditions.
Conclusion: It is evident through the results that smoking is very common among doctors, especially men, and smoking is more common among people over 55 years of age than others.
In addition to these negatives, most of the sample is aware of the negative aspects of smoking and its risks in the future, but the majority of them still smoke.
Finite Element Analysis on All on Four Implant Screw Retained Mandibular Fixed Prosthesis. (Material Selection Role)
Authors: Salah A. Youssef  , Mohammed Galal Rami , Ghada E. Hamza  , Ghith Fayez Saeed Aldhahri  , Ahmad Ramzi Abdu Alzaylaei  , Mohammed Saleh Mohammed Alamoudi  , Abdullah Abdulrahman Ahmad Benjabi  , Yousef Hatem Jayar  , Ammar Abdulrahim Abdulqahhar Khoja  , Ahmad Mohammad Salem Alsaiary  , Muhanad Naser Aljuhani  , Abdulrahman Omar Ali Sanyour  , Bader Obidullah Alkhozai  , Adnan Madani Mohammed Khamis  , Salma Sulaiman Alghalayini
Published: September 2021

Aim: to indicate the importance of adequate selection of all on four-fixed implant supported hybrid mandibular prosthesis material to reduce bone stresses. Materials and methods: one three-dimensional simplified geometric model, for bone and fixed prosthesis, was created by using engineering CAD/CAM software. On the other hand, implant system manufacturer data gave sufficient geometrical data to model it exactly. The modelled part was transferred to ANSYS for assembly, meshing, and analysis. Three overlying materials were tested; Acrylic, Polycarbonate, and Zirconia above the cobalt chromium bar. The lowest area of the cortical bone was set to be fixed in place as boundary condition. While unilaterally load of 250N was applied vertically on central fossa of first and second molars as two loading cases. Results: changing overlying material resulted in, cortical bone and implant complex receiving Von Mises stress in sequence with material rigidity. The more rigid the overlying material the less bone stresses with first molar loading, while, opposite trend (sequence) appeared with second molar loading. On the other hand, bar, coping, screws, mucosa, and spongy bone deformations and stresses decreased with increasing overlying material rigidity. Where, all the model components showed stresses and deformations within the physiological limits. Conclusions: More rigid overlying material is recommended to reduce stresses on bar, coping, screws, mucosa, and spongy bone. Overlying material selection for cortical bone and implant complex is extremely tricky. That it showed same behaviour as other soft tissues with applying load close to the bar (short cantilever arm), then inverted behaviour with shifting the applied load away from first to second molar (increasing cantilever arm).
The Effects of Chemical Disinfection on Dimensional Stability among Different Type of Impression Addition Silicon Materials
Authors: Salah A. Yousief  , Khames T. Alzahrani  , Suha M. Alhuwairini  , Fai Y. Alharbi  , Dalal A. Eissa  , Sara M. Almojaddidi  , Maha A. Almalki  , Waad E. Alsulami  , Waad K. Alsaiari  , Abdullah J. Algharamah  , Abdulrahman O. Sanyour  , Bashayir G. Althagafi  , Mamoun M. Abo Khalil
Published: September 2021

Introduction: Saliva and blood contaminated impressions are often a source of cross contamination between the clinic and dental laboratory. Explicit communication and observance of an infection control protocol for handling of dental impressions must exist among the office staff as well as between office and dental laboratories. Though disinfection of impression is routinely followed, autoclaving elastomeric impression is an effective method of sterilization them. Objectives: The purpose of this study was to evaluate dimensional stability and detail reproduction of a new addition silicon impression material after disinfection. Methods: In this study, a total of twenty impressions for the master model using heat resistant plastic stock trays. The twenty impressions were divided into two groups according to disinfection technique: (Table 2) Group 1: (n=10) Control group, untreated impressions. (C.G) Group 2: (n=10) Impressions were chemically disinfected. (D.G). after all impressions treatment, they were poured with extra hard stone (type IV) to get stone casts. Dimensional accuracy and detail reproduction of the impression material were evaluated indirectly through the recovered improved stone casts from impressions of the master model using the travelling microscope. Results: Cross arch distance (A): Epoxy resin master model cross arch distance measurement (A) was (41.36 mm). 1.1 Measurements of the cross-arch distance of stone casts Control group (C.G): The mean and standard deviation values of distance (A) in stone models obtained from C.G. were 41.553 ± 0.170 mm. Disinfection group (D.G): The mean and standard deviation values of distance (A) in stone models obtained from D.G were 41.368 ± 0.083 mm. ANOVA test showed that there was a statistically difference shrinkage between the groups (P-value = 0.006). 1.2 Measurement of the dimensional changes in the cross-arch distance of the different groups. The mean and standard deviation values of cross arch distance changes in stone models of C.G. were 0.191 ± 0.170 mm. while dimensional changes in stone models obtained from D.G. were 0.006 ± 0.082 mm. Conclusion: The purpose of this study was to evaluate dimensional stability and detail reproduction of a new addition silicon impression material after disinfection. In this study an epoxy resin master model was duplicated from a modified dentate mandibular model. Within the limitations of this study, it could be concluded that Chemical disinfectant of polyvinyl siloxane impression material can be successfully used in making fixed partial dentures.
Laminin - A Prognostic Marker in Oral Squamous Cell Carcinoma
Authors: Dr. Sushanta Kumar Singh  , Dr. Gayatri Rath  , Dr. Ashok Kumar Panda
Published: September 2021

Introduction: Squamous cell carcinoma is one of the most common malignant tumours of the oral cavity and is the tenth most common cause of death worldwide. Because of the high malignant potentially these cases are detected at an advanced stage. Also the recurrence rate is high which invites challenge to the treating surgeon. Laminin, a basement membrane molecule is a reliable marker to predict dif-ferentiation and aggressiveness of the oral squamous cell carcinomas. Methods: The study was conducted in the department of pathology, S. C B Medical College, Cuttack with an aim to predict the tumour aggressiveness and thereby prognosis. A total number of 76 cases were studied using the laminin immunostaining and the results tabulated and interpreted. Results: Majority were well differentiated squamous cell carcinomas, which showed mild to moderate intra cytoplasmic staining of laminin and an intense staining at the tumour host interface, in contrast to an intense intra cytoplasmic staining in poorly differentiated squamous cell carcinoma cases. Those with lymph node metastasis and involved surgical margins also showed intense intra cytoplasmic laminin staining pointing to a higher grade tumour. Conclusion: Laminin immunostaining is definitely superior to the conventional staining procedures for the as-sessment of tumour aggressiveness and differentiation, intra-operative assessment of tumour excision margins and thus access prognosis. Recent researches highlight on Laminin antibodies, which can be used as specific chemotherapeutic agents, to check the process of tumour growth and invasion.
The Role of Chest X-Ray in Intensive Care Unit
Authors: Mayson Ahmed Wanasi Khair  , Shouq Mohammed Alamri  , Ahlam Hameed Alrashidi  , Malak Abdulrahman Lharbi  , Yosra Saleh Al-moghamsi  , Mashaeel Musallam Alharbi
Published: September 2021

Purpose: Chest X-rays (CXRs) are the most common radiological tests performed in the intensive care unit (ICU). The purpose of the current study was to investigate the relationship between the performance CRX in ICU and the patient’s confirmed pathologic finding. Methods: This retrospective study was evaluated 50 ICU chest X-rays were retrieved from the Picture Archiving and Communication System (PACS) of the different Saudi Hospitals in Al-Medina (February - April 2017). Frequency Distribution, Ratio and Linear Regression were used for statistical analysis. Result: This study demonstrated that based on analyzing the data, 92% of chest X-ray requests were used among 50 ICU patients to confirm the diagnosis, and a significant relationship was found between the use of chest X-rays between the ICU patients and the patient's confirmed pathologic finding which may mean that chest X-ray had a great role in confirming the disease or its complications. There has been a recommendation to perform daily CRX for patients with severe cardiopulmonary disease or receiving mechanical ventilation, as well as immediate CXR imaging for all patients who have had endotracheal tubes, feeding tubes, vascular catheters, and chest tubes. The most effective principle of radiation protection is distance, when performing an X-ray, the technologist must be at least six feet (1.5 to 2 m) from the radiation source. If the technician needs to be close to the radiation source, wearable lead shields and thyroid collars can protect the radiation-sensitive areas of the body. Conclusion: The chest X-ray of ICU patients was an important diagnostic tool that would affect patient management; however, it may also be a tool that can lead to serious complications for patient. A small sample size was used in this investigation that results in unconfirmed information, the future research using a large sample size is needed to carry out a more reliable and valid information.
Clinical Application of Genetic Prediction in the Management of CAD
Authors: Robert Roberts  , Jacques Fair
Published: September 2021

Sequencing of the human genome followed by the HapMap project made possible the unbiased genome-wide association studies that led to the discovery of hundreds of genetic risk variants predisposing to CAD. The total genetic risk for CAD can be expressed in a single number based on the number of variants inherited. A GRS derived from genotyping with microarrays containing these risk variants has been evaluated in over 1 million individuals. Risk stratification for CAD based on the GRS was shown to be superior to conventional risk factors. Placebo-controlled clinical trials showed individuals with high genetic risk had a 40-50% reduction in cardiac events with a favorable lifestyle, and cholesterol-lowering drugs. The risk of CAD based on conventional risk factors such as hypertension are age-dependent, occurring primarily in the sixth or seventh decade which is too late for primary prevention. The GRS is independent of age and can be determined at birth if needed. Incorporation of the GRS into clinical practice would transform the primary prevention of CAD, the number one killer.
Giant Encapsulated Anterior Abdominal Wall Haematoma Complicating Mesh Incisional Hernia Repair: Challenges of Management in a High-Risk Term Pregnancy in a Low Resource Setting
Authors: Anwar Sadat Seidu  , David P. Suoseg  , Bernard N. Maanikuu  , Musah Yakubu  , Imoro Osman  , Emmanuel A.N. Azure  , Haruna Danamiji Osman  , John F. Busuuri  , Abdul-Latif Alhassan  , Abdul Aziz Ewura  , Gerald Batariwah  , Munkaila Adam  , Mohammed I. S. Bukari  , Abdul-Jalilu Muntaka Mohammed  , Der EM
Published: September 2021

Giant encapsulated haematoma of the anterior abdominal wall is an unusual complication of mesh incisional hernia repair. The commonest symptoms are swelling and pain. It can be diagnosed with ultrasonography and Computed Tomography (CT) scan. The objective of this case report is to illustrate the challenges of management of a complex pathology in a high-risk term pregnancy.
In this case report, a 28-year-old morbidly obese multiparous woman with two previous ventral wall hernia repairs and two previous caesarian sections, presented at term to the prenatal clinic with protruding anterior abdominal mass. Initial preoperative diagnosis aided by ultrasonography was a herniated term gestation through an incisional hernia. Intraoperatively, the surgical team was faced with the challenge of managing a longstanding giant organized haematoma of the anterior abdominal wall and the anticipation and prevention of obstetric complications associated with two previous caesarian sections and a big baby. This report illustrates that good clinical assessment combined with sonographic assessment of complex cases by an experienced radiologist is crucial to avoid missed diagnosis. A multidisciplinary team management was essential for a successful outcome.
Srategi Pemanfaatan Instagram Sebagai Media Periklanan
Authors: Salma Saffanah
Published: September 2021

This research aims to find out the right strategy in using Instagram as an advertising medium for MSMEs in Amoira using descriptive qualitative methods. The data is taken by doing two ways, namely interviews and also observations. The data obtained is processed by several methods such as internal resources analysis, Sustainable Competitive Advantage (SCA) analysis, VRIO framework, and also TOWS analysis. Then the researchers conducted a content analysis to propose strategies for using Instagram. In this study, generate strategies that can be carried out based on the analysis conducted on Amoira.

Keywords: instagram utilization strategy, advertising media, impression

Abstrak

Penelitian ini bertujuan untuk mengatahui apa strategi yang tepat dalam pemanfaatan Instagram sebagai media periklanan pada UMKM Amoira menggunakan metode kualitatif deskriptif, data diambil dengan melakukan 2 cara yaitu wawancara dan juga observasi. Data yang diperoleh diolah dengan sejumlah metode seperti analisis internal resources, analisis Sustainable Competitive Advantage (SCA), framework VRIO dan juga analisis TOWS. Kemudian peneliti melakukan analisis konten untuk mengusulkan strategi pemanfaatan Instagram. Pada penelitian ini, menghasilkan strategi-strategi yang bisa dilakukan berdasarkan analisis yang dilakukan pada Amoira.

Kata kunci: strategi pemanfaat instagram, media periklanan, impression
Nominales cardinales como predicados colectivos
Authors: Barcelo Aspeitia Axel Arturo
Published: September 2021

Propongo un mecanismo semántico novedoso para explicar que cuando expresiones cardinales complejas como menos de diez meses o entre dos y cinco veces se combinan con predicados distributivos –pero no cuando se combinan con predicados no distributivos– imponen un límite cardinal superior. Mi explicación se basa en el simple hecho de que los predicados distributivos y los no distributivos tienen diferentes dominios de denotación y que, por lo tanto, cuando combinamos predicados de ambos tipos, es necesario hacer algún tipo de ajuste de dominio. Esto es exactamente lo que sucede cuando los predicados cardinales, –que no son distributivos– modifican pronominalmente algún predicado distributivo. Una vez que se reconoce esta necesidad de ajuste de dominio, el comportamiento de los términos cardinales complejos deja de ser desconcertante. Para realizar este ajuste de dominio, mi propuesta introduce un operador silencioso de totalización que asigna a toda propiedad plural distributiva P la propiedad plural colectiva de ser todos los Ps.
Modification of the Concept of Trust in the Organization
Authors: BAZAROV Tahir , GEVORGYAN Srbuhi , KARAPETYAN Vladimir , KARIEVA Nazakat , KOVALENKO Larisa , DALLAKYAN Alla
Published: September 2021

One of the crucial factors determining the state and level of the organization in the market is the trust in the organization. The work aims to modify and improve the concept of trust in the organization by R. Shaw and to develop a methodology for identifying ideas about trust in the organization. Based on R. Shaw’s “Methodology for assessing the level of trust in the organization” and the three key imperatives of trust, 20 unfinished sentences were developed, each of which had to be completed with one or more words/phrases, based on the respondents’ perceptions and what is characteristic of them. Based on the results obtained at the first stage of the study, statements were developed that were included in the questionnaire. As a result of processing the obtained data through content analysis, the following components were identified in the structure of each imperative of trust: effectiveness, decency, caring for others. A methodology for identifying beliefs was developed and tested for reliability-consistency. In the modified concept of R. Shaw, the selected components can be correlated with three group roles that a successful leader should have: facilitator, mediator and moderator.
The Isolationist Pathology of Sovereignism (Three Historical Cases for Analysis)
Authors: LEPSKA Natalia , LEPSKYI Maksym , YATSYNA Yuliia , KUDINOV Igor
Published: September 2021

The article examines the isolationist pathology of sovereignism in the loss of subjective capacity in the changing political reality. The article aims to study the isolationist policy of sovereignism, the consequences of which are considered a pathology of the countries’ social organism. The study was carried out in the analytical strategy of searching for the measure of sovereignism and its pathology, in the search for the general, special and singular in specific historical cases of isolationism of states.
The authors found out that sovereignism differs in quality, the degree of implementation in achieving the integrity of society and government, solving the problem of superiority, equality and inequality of states, their influence and efficiency. States, depending on the degree of sovereignism, are classified into 1) rogue countries, 2) colonial countries, 3) countries under external control, 4) regional leaders and 5) su­perpowers. States differ according to the measure of sovereignism: 1) with developed sovereignism, 2) de­veloping sovereignism, 3) with destroyed sovereignism and statehood; 4) with undeveloped sovereignism and statehood; 5) with chaotic sovereignism. Scientific intelligence has made it possible to actualize the issue of the predictive study of the isolationist policy consequences at all levels of political reality in order to make appropriate strategic decisions.
Modeling of Information Support for the Development of Creative Abilities in Students in the Context of Philosophy Education
Authors: KVAS Olena , HORODYSKA Violeta , IVAKH Svitlana , FEDOROVYCH Anna , ZEMAN Ivanna , SVISTELNYK Iryna
Published: September 2021

Creativity is defined as a general ability that combines general intelligence, personality traits, and the ability to think productively. The creativity of psychology students is a mandatory characteristic of a holis- tic personality because of the appropriate psychological and pedagogical conditions and the high level of formation of his professional and personal qualities. The purpose of the article is to systematise the process of increasing the creativity of psychology students with the help of mechanisms and elements of the func- tional model of IDEF0 in the context of the philosophy of education. It allows us to improve the process of developing students’ creativity by using the modern management model IDEF0, which is unique and in- teresting. For the specification of the methodology for increasing creativity among psychology students, it has been chosen the methodology of functional modelling and a graphical description of processes (IDEF0). The article considers the specifics of students of higher educational institutions and psychologists in particular. In the future, the IDEF0 model should be applied to other students in the context of the phi- losophy of education.
Socio-Ecological Effect of Public Management of Green Development in the Context of the Philosophy of Modern Ecology
Authors: KRYSHTANOVYCH Myroslav , GOLUB Valeriia , KОZAKOV Volodymyr , PAKHOMOVA Tetyana , POLOVTSEV Oleg
Published: September 2021

In recent years, the idea of Green economy has been widely discussed by experts in environmental economics and in various political forums. Many countries use various tools and principles of Green economy in their national policies and growth strategies. However, some countries fear that the transition to a Green economy model may hamper their development in the context of the philosophy of modern ecology. That is why the formation of a clear methodology for the Green economy is essential today. The article discusses the prerequisites for implementation, the basic principles of Green economy into the pub- lic administration system, and provides a system for modelling ways to implement the principles of Green economy using the IDEF0 methodology in the context of the philosophy of modern modern philosophy ecology. This methodology allows seeing clearly the ways and means of achieving this goal.