bluuebunny/crossref_metadata_2025 huggingface dataset:
A Projection Analysis of News Critical Literacy Among Chinese EFL Learners: An SFL Approach
Authors: Luo Zaibing , Xie Pan
Published: February 2025

Critical literacy in EFL context has been examined from different perspectives. However, there is limited empirical evidence of how news critical literacy is examined discursively among college EFL learners. By deploying a Projection profile from Systemic Functional Linguistics, this paper contributes to the written evaluation of college EFL learners’ news critical literacy. The data consisted of 236 news critiques from two cohorts of Chinese EFL learners. The results show that college EFL learners in China are more subjected to the projection of locution and subjective-implicit projection in news critiques, presenting similar choices about projection grammar but reverse orientations in news criticizing context. Moreover, Chinese EFL learners are adept in projecting function for iconic sequencing of information, text sharpening, message retrospecting, and co-textual reasoning, manifesting a critical awareness in functional literacy of news discourse. Various projections also place Chinese EFL learners into a cline of discursive identities among projectors, speakers and discoursal community members, which indicates that Chinese EFL learners are disengaged in discerning news information and passive on news values and social context. The findings implicate that a projection-based trinocular lens is a discursively effective approach for delimiting Chinese EFL learners’ news critical literacy while corroborating that discursive technology, contextual orientation and critical awareness are crucial elements in news critical literacy. Pedagogical implications for news literacy education and media communication toward EFL learners are also discussed.
Sexual Functioning Among Drug-Naive Females with Depression at Tertiary Care Unit of North India: A Cross-Sectional Study
Authors: Prabhu Pooja Gloria , Devi Shyama , Kar Sujita Kumar , Mishra Sudha
Published: February 2025

Introduction:

Depression is a widespread issue among women in India, affecting all age groups. It can lead to sexual dysfunction, which is more commonly found in females than males, but often goes unreported. The purpose of the study was to evaluate the sexual functioning of females with depression.

Methods:

The study utilized a cross-sectional research approach to assess 60 females who were diagnosed with depression according to International Statistical Classification of Diseases, Tenth revision (ICD-10) in a psychiatric outpatient department (OPD). The assessment included the use of Mini International Neuropsychiatry Interview (MINI) 6.0.0 screener, sociodemographic and clinical variables, Hamilton Depression Rating Scale (HAM-D) scale, and Female Sexual Functioning Index (FSFI). The study sample only included married females who were drug-naive for the last three months, stayed with their husband for the majority of the time, and were willing to participate in the study.

Results:

The FSFI test revealed that 61.67% of the participants experienced sexual dysfunction across all domains, with the greatest impact observed in the desire, arousal, and orgasm domains. Lower mean percentages were indicative of more severe sexual dysfunction. Correlation analysis revealed a weak negative relationship between age, the severity of depression, and the duration of the current episode with sexual functioning; however, the results were not statistically significant.

Conclusion:

According to this study, depressed females experience sexual dysfunctions. Therefore, healthcare providers should ask and consider the sexual aspect while treating patients with depression. Identifying, discussing, and managing problems related to sexual health at an early stage are crucial.
Factors Militating Against Utilization of Male Condom in the Prevention of STDs Among Youths
Authors: Godwin Otioro Jane , Tovia Jedege , Adeshola Adebayo Gift
Published: February 2025

Despite the effectiveness and widespread availability of condoms in recent times, their usage has remained inconsistent among the youth population, thereby contributing to the increased spread of sexually transmitted diseases (STDs). This study therefore identifies and examines the factors that militate against the utilization of male condoms in the prevention of STDs, providing relevant recommendations for enhancing the prevention efforts of STDs among youth. Our research found that despite adequate knowledge about the range of benefits of condom use among youth, the presence of societal and cultural norm stigmas against its use, psychological factors such as perceived reduced sexual pleasure or discomfort during its use, and accessibility constraints such as cost and unavailability in some communities are some of the prominent factors militating against the utilization of male condom. In order to further enhance the utilization of male condom among youth, this research therefore delivers a context-specific analysis that comprehensively integrates socio-cultural, educational, and psychological barriers, offering a nuanced understanding in under-researched rural contexts. Finally, our study suggests the need for targeted interventions, emphasizing on challenging global social norms, comprehensive sexual education, safe sexual practice, and improving condom accessibility in rural communities, as these strategies are essential for reducing STD transmission in youth population.
Quality of guidelines for infection management in sepsis: a critical appraisal using the AGREE II instrument
Authors: Yang Guo-Xun , Que Ting , Wang Yi-fei , Liu Xiao-Bo , Dou Shu-Qian , Pu Shi-Ling , Wang Xin , Wu Kong-Jia , Wang Yuan , Wang Qi , Liu Wen-Jun
Published: February 2025

Objectives

The aim of this study was to systematically assess the methodological quality of current sepsis infection management guidelines and identify gaps in knowledge that limit evidence-based practice.

Methods

A systematic search was conducted to obtain guidelines for the management of sepsis infections (2012–2021), and three reviewers independently assessed the quality of eligible guidelines using Appraisal of Guidelines for Research and Evaluation (AGREE II) tool. The intraclass correlation coefficients (ICCs) were used to measure the agreement between reviewers. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach was used to analyze the strength of recommendation and level of evidence of the guideline, and the number of recommendations, strength of recommendation, and level of evidence were determined.

Results

Eleven guidelines for the management of sepsis infection were identified. An overall high agreement among the evaluators for each domain was observed (ICC ranged from 0.850 to 0.959). The overall scores of the included guidelines were all over 60% (range, 62.3-89.90%), which were worthy of recommendation for clinical use; among them, 4 guidelines had an overall score of over 80%, which were high-quality guideline articles. In terms of the quality domains of the guidelines, the scope and purpose domain and the clarity of expression domain had the highest average scores, which were 93.6% (range, 79.6–98.1%) and 91.4% (range, 64.8–98.1%), respectively, while the applicability domain had the lowest average score, which was 64.8% (range, 51.4–76.4%). The strength of the recommendations of the guideline recommendations was mainly weak, accounting for 73.4%; the level of evidence cited was mainly very low quality (60.2%) and low quality (28.1%).

Conclusions

The quality of sepsis infection management guidelines varies, but the overall quality level is satisfactory. Improving the low-quality areas of sepsis guidelines, attempting to resolve existing problems and controversies, and improving the quality of research evidence will be effective ways for developers to upgrade sepsis guidelines.
Role and competency model for coordination tasks in municipal health promotion: findings from an integrative review
Authors: Tollmann Patricia , Dieterich Sven , Kuchler Maja , Leimann Janna , Lubosch Laura , Mielenbrink Vivien , Rangnow Pia , Terhorst Stefanie , Quilling Eike
Published: February 2025

Background

Integrated municipal health promotion is becoming increasingly important in promoting health equity. Successful implementation of integrated municipal health promotion processes requires a central coordinator. Therefore, this study investigates which competencies are necessary to successfully manage the extensive coordination tasks. The aim is to present the necessary roles and competencies in a way that can be applied in practice.

Methods

An integrative review was conducted. As a first step, a systematic search was carried out in the databases LIVIVO, Web of Science and via the EBSCOhost platform (including APA PsycInfo, ERIC, MEDLINE, CINAHL, APA PsycArticles, SocINDEX) using various inclusion and exclusion criteria (e.g. English and German language). The steps of systematic data extraction, data evaluation and data analysis were subsequently carried out. In accordance with the integrative review method, the data were then iteratively compared and synthesised, followed by the final step of presentation and integration in the form of a new model.

Results

According to the pre-defined inclusion and exclusion criteria, 12 hits were included. The results identified were combined into a concept for a role and competency model. Central competencies for the coordination of municipal health promotion are e.g., public health expertise, interprofessional competencies as well as coordination, communication, and management competencies.

Conclusions

The role and competency model presents the roles and competencies needed to coordinate integrated municipal health promotion processes and emphasises the need to work intersectorally. The model provides a guide for practical application and can contribute to the selection of qualified staff, professionalisation, training and curriculum development. It can make a quality-assured contribution to the structural development of integrated health promotion at local level. Further research is needed to validate the model in practice.

Trial registration

This integrative review was not registered beforehand.
Exploring the therapeutic potential of marjoram (Origanum majorana L.) in polycystic ovary syndrome: insights from serum metabolomics, network pharmacology and experimental validation
Authors: Elfiky Aliaa M. , Ibrahim Reham S. , Khattab Amira R. , Kadry Mai O. , Ammar Naglaa M. , Shawky Eman
Published: February 2025

Background

Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder with significant metabolic and hormonal dysregulation. Marjoram (Origanum majorana L.), known for its medicinal properties, has potential in managing PCOS through various bioactive compounds.

Objective

This study aims to evaluate the effects of marjoram on PCOS symptoms using serum pharmacochemistry, network pharmacology, and molecular docking in a DHEA-induced rat model.

Methods

Polycystic Ovary Syndrome (PCOS) was induced in rats using dehydroepiandrosterone (DHEA). Marjoram’s therapeutic effects were evaluated by analyzing oxidative stress biomarkers, hormone levels, and ovarian histopathology. Untargeted serum metabolomics, conducted with ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC TQD-MS/MS), identified key bioactive compounds. These compounds were then examined through network pharmacology to map their interactions with PCOS-related pathways, with findings validated via molecular docking.

Results

Marjoram treatment significantly reduced oxidative stress by decreasing nitric oxide (NO) and increasing total antioxidant capacity (TAC). Hormonal analysis revealed that high-dose marjoram (100 mg/kg) normalized progesterone, estradiol, testosterone and FSH levels. Body weight gain was also reduced with marjoram treatment, especially at the higher dose. Histopathological evaluation showed fewer ovarian cysts and improved follicular structure with marjoram administration. Network pharmacology analysis highlighted the steroid hormone biosynthesis and estrogen signaling pathways as critical targets, with apigenin and oleic acid identified as active compounds. Molecular docking confirmed strong interactions of these compounds with core PCOS-associated proteins, further supporting marjoram’s potential in modulating PCOS symptoms.

Conclusion

This study reveals that marjoram contains a diverse range of active compounds that can modulate crucial biochemical and histological markers related to PCOS. By combining serum pharmacochemistry with network pharmacology, the research highlights marjoram’s potential as a natural supplement to help alleviate PCOS symptoms and slow the syndrome’s progression. These findings support further investigation into marjoram’s role as a complementary therapy for managing PCOS.
Proteomics revealed novel functions and drought tolerance of Arabidopsis thaliana protein kinase ATG1
Authors: Cheng Shan , Fan Siqi , Yang Chao , Hu Weiming , Liu Fen
Published: February 2025

ATG1 stimulates autophagy biogenesis and serves as a gatekeeper for classical autophagy. To obtain insight into the control of autophagy by ATG1 and determine whether ATG1 has broader processes, we performed a thorough proteomics analysis on the Col-0 wild-type and atg1abct mutant in Arabidopsis thaliana. Proteomic data analysis pointed out that ATG1 has an unidentified function within the inositol trisphosphate and fatty acid metabolism. We also discovered ATG1-dependent autophagy has an emerging connection with ER homeostasis and ABA biosynthesis. Moreover, Gene Ontology terms for abiotic and biotic stress were strongly enriched in differentially abundant proteins, consistent with the reported role of canonical autophagy in these processes. Additional physiological and biochemical analysis revealed that atg1abct exhibited stronger drought resistance under both PEG-simulated drought treatment and natural drought stress. Results from DAB staining also indicated that atg1abct accumulation fewer ROS than Col-0 following drought treatment. As a result, these results illuminate previously unknown functions for ATG1 and offers novel perspectives into the underlying processes of autophagy function.
Functional characterization and evolution of olfactory responses in coeloconic sensilla of the global fruit pest Drosophila suzukii
Authors: Xue Qi , Hasan Kazi Sifat , Dweck Omar , Ebrahim Shimaa A. M. , Dweck Hany K. M.
Published: February 2025

Background

When a species changes its host preference, it often requires modifications in its sensory systems. Many of these changes remain largely uninvestigated in the global fruit pest Drosophila suzukii (also known as spotted wing Drosophila, SWD). This species, which shares a last common ancestor with the model organism D. melanogaster—a species that prefers overripe fruits— ~ 15 million years ago, has shifted its preference from overripe to ripe, soft-skinned fruits, causing significant damage to fruit industries worldwide.

Results

Here, we functionally characterized the coeloconic sensilla in D. suzukii and compared their responses to those of its close relatives, D. biarmipes and D. melanogaster. We find that D. suzukii’s responses are grouped into four functional types. These responses are consistent across sexes and reproductive status. The odorant receptor co-receptor Orco is required for certain responses. Comparative analysis across these species revealed evolutionary changes in physiological and behavioral responses to specific odorants, such as acetic acid, a key indicator of microbial fermentation, and phenylacetaldehyde, an aromatic compound found in a diverse range of fruits. Phenylacetaldehyde produced lower electrophysiological responses in D. suzukii compared to D. melanogaster and elicited strong attraction in D. suzukii but not in any of the other tested species.

Conclusions

The olfactory changes identified in this study likely play a significant role in the novel behavior of D. suzukii. This work also identifies phenylacetaldehyde as a potent attractant for D. suzukii, which can be used to develop targeted management strategies to mitigate the serious impact of this pest.
Impacts of vaping and marijuana use on airway health as determined by exhaled breath condensate (EBC)
Authors: Rojas Dante E. , McCartney Mitchell M. , Borras Eva , Hicks Tristan L. , Lam Tiffany T. , Kenyon Nicholas J. , Davis Cristina E.
Published: February 2025

Across the United States, there is increased use of cannabis products and electronic delivery systems for cannabis products and nicotine, yet little is known about their impacts on lung health. We analyzed exhaled breath condensate of 254 participants who were non-users and users who used cannabis and tobacco products. The 132 participants reported using a product (“users”) were distributed into cohorts of tobacco products and cannabis products, with some participants following into multiple cohorts. Targeted analysis of inflammatory oxylipins found up-regulation among persons using tobacco products, while cannabis users had concentrations closer to nonusers, and often down-regulated. Untargeted screening of 403 significant metabolites found tobacco users had similar breath profiles, and that cannabis users had a similar profile that was closer to the profile of nonusers. Metabolites were significantly higher in breath of people using combustion products (tobacco and cannabis) relative to nonusers, and significantly lower in e-device users (nicotine and THC). Our work demonstrates the relative impact of e-delivery systems and cannabis products compared to traditional cigarette smoking on lung metabolic profiles.
Is meeting 24-hour movement guidelines associated with a lower risk of frailty among adults?
Authors: Liu Yuhang , Gao Siyao , Dou Zhigang , Chen Zhen , Tang Jialing
Published: February 2025

Background

The relationship between 24-hour (24-h) movement guidelines and frailty remains unclear. We aimed to investigate the associations between meeting 24-h movement guidelines and frailty and to conduct secondary analyses by age, gender, and ethnicity.

Methods

In this study, we extracted data from the National Health and Nutrition Examination Survey (2007–2018) database. A total of 5,726 participants (50.25 ± 0.31 years) were included in this analysis, representing 38,240,356 noninstitutionalized U.S. individuals. Three 24-h movement behaviors, namely, physical activity, sedentary behavior (SB), and sleep, were self-reported using the standardized questionnaires. The 49-item frailty index was used to measure frailty. Multivariable logistic regression models and trend tests were used to examine the associations between meeting 24-h movement guidelines and frailty. Sensitivity analyses were also conducted to ensure the robustness of our results.

Results

The total age-adjusted prevalence of frailty was 30.5%. In the fully adjusted model, compared with not meeting any of the 24-h movement guidelines, the adjusted odds ratios (AORs) of frailty were 0.786 (95% CI: 0.545, 1.133), 1.161 (95% CI: 0.787, 1.711), and 0.915 (95% CI: 0.616, 1.358) for participants meeting only moderate to vigorous physical activity (MVPA), only SB, and only sleep guidelines, respectively, but no statistically significant differences were observed (all P values > 0.05). Participants who met the SB + sleep guidelines (AOR = 0.613, 95% CI: 0.423, 0.887), MVPA + sleep guidelines (AOR = 0.389, 95% CI: 0.255, 0.593), and MVPA + SB guidelines (AOR = 0.555, 95% CI: 0.383, 0.806) presented a significantly lower risk of frailty by 39%, 61%, and 45%, respectively. Meeting all 3 guidelines (AOR = 0.377, 95% CI: 0.264, 0.539) and meeting 2 guidelines (AOR = 0.527, 95% CI: 0.377, 0.736) were associated with a lower risk of frailty (P value < 0.001), showing a linear trend (P for trend < 0.001). The strength of these associations varied somewhat by age, gender, and ethnicity.

Conclusions

Significant associations between the 24-h movement guidelines and frailty were observed among U.S. adults. Future studies are warranted to examine the causality and trajectory of these associations.
Contraceptive decision-making and its association with contraceptive use among married adolescent girls in Niger
Authors: Silverman Jay G. , Tomar Shweta , Brooks Mohamad I. , Aliou Sani , Johns Nicole E. , Challa Sneha , Shakya Holly Baker , Boyce Sabrina C. , Raj Anita
Published: February 2025

Objective

Niger has among the highest rates of child marriage and lowest rates of modern contraceptive use in the world. This study analyzes the association between contraceptive decision-making and contraceptive use among married adolescent girls in rural Niger, including multiple assessments of decision-making and consideration of overt vs. covert contraceptive use.

Methods

We analyzed cross-sectional survey data collected from married adolescent females (n = 823) participating in the third round of data collection (October–November 2019) for the cluster-randomized controlled trial of a family planning intervention study. Contraceptive decision-making measures assessed participants’ (a) participation in contraceptive decision-making, (b) final say in decision-making in case of spousal disagreement, and (c) satisfaction with participation in decision-making. Outcomes include contraceptive use ever categorized based on whether use was overt (with husband’s knowledge) or covert (without husband’s knowledge). Adjusted multinomial logistic regression models were used to test the associations between each decision-making item and each type of contraceptive use.

Results

Over half of participants reported ever using a contraceptive (59%) and that their husbands were the sole decision-makers regarding contraceptive use (60%). Adolescents’ participation in decision-making was negatively associated with overt contraceptive use (ARRR = 0.41; 95%CI = 0.19–0.91) and positively associated with covert contraceptive use (ARRR = 8.76; 95%CI = 2.45–31.30). Women reporting joint decision-making were more likely to report covert use vs. no use (ARRR = 3.20; 95%CI = 1.14–8.99). Women having final say in contraceptive decision-making in case of disagreements were more likely to report covert contraceptive use over no use (ARRR = 9.14; 95%CI = 3.17–26.40). Women’s satisfaction with decision-making was positively associated with contraceptive use ever (AOR = 2.72; 95%CI = 1.80–4.16), and overt (ARRR = 2.68; 95%CI = 1.75–4.01) and covert contraceptive use (ARRR = 10.9; 95%CI = 2.16–54.80).

Conclusion

Male control over decision-making and female satisfaction with decision-making are associated with greater contraceptive use. Findings indicate that women’s control over decision-making, and its relation to contraceptive use, is complex and requires more nuanced understanding for married adolescents.
Psychopathological symptoms in school-aged children after a traumatic event
Authors: Plümacher K. S. , Loy J. K. , Bender S. , Krischer M.
Published: February 2025

Background

Traumatic experiences in childhood can have far-reaching and serious consequences for the development of those affected. Little is known about the age- and sex-specific symptom patterns in children and adolescents following a traumatic event. These do not always manifest in symptoms that meet the diagnostic criteria for post-traumatic stress disorder according to ICD 10.

Methods

In an outpatient cohort of 84 children and adolescents aged 6 to 18 years, we utilised the dimensional Child Behaviour Checklist (CBCL) to analyse symptoms occurring within twelve months of a traumatic event as defined in ICD 10. Regression models were applied to examine the effects of sex, age, and their interaction. CBCL (sub-)scales from caregivers served as the outcome variables.

Results

The most severe symptoms were externalising symptoms found in boys aged six to below twelve years, while girls of the same age showed the fewest symptoms. No fully consistent picture regarding age- and sex-effects was found across the (sub-)scales, however, the most consistent finding for all scales was an interaction between age and sex, resulting in a convergence between boys and girls with age. Adolescent males and females were affected to a similar extent.

Conclusion

Knowledge of age- and sex-specific patterns in children and adolescents following a traumatic event is essential to recognise possibly trauma-related symptoms at an early stage, initiate adequate treatment. Considering that trauma can exacerbate or complicate externalising symptoms, and vice versa, it is crucial to integrate trauma-specific interventions into the treatment plan for those affected. Developing comprehensive, age- and sex-specific diagnostic criteria for trauma-related disorders might not only improve early detection and treatment but also ensure that interventions address both emotional and behavioural dimensions effectively. Future research should focus on refining these criteria and exploring the interplay between trauma and co-occurring conditions to enhance treatment outcomes.
Age-specific familial risks in cancer as clues to germline genetic and environmental causes: focus on colorectal, endometrial, prostate, kidney, breast and lung cancers
Authors: Hemminki Kari , Försti Asta , Hemminki Otto , Scott Rodney J. , Hemminki Akseli
Published: February 2025

Background

The Swedish Family-Cancer Database (FCD) is the largest source of data on familial cancer in the world, including practically complete family structures and individual cancer diagnoses from the high-quality cancer registry. We present a novel application of FCD by analyzing age-specific familial risks and interpreting them through likely causes, such as germline pathogenic variants and/or environmental exposures.

Main body

The basic assumption for this approach is that a discrete familial clustering in a narrow age-interval is not random but may provide causal clues. For this analysis we selected reasonably common cancers to meaningfully scrutinize familial risk through adulthood in which cancers are diagnosed, that included colorectal (CRC) and endometrial cancers, prostate and kidney cancers and breast and lung cancers. The interpretation is based on the literature. The highest familial relative risks for CRC and endometrial cancers were found at ages 40–44 years, matching the peak impact of mismatch repair gene mutations. However endometrial cancer showed also a small early onset component which could not be explained. Age-related familial risks for breast, prostate and kidney cancers also matched data from large-scale sequencing; these included the early onset component in kidney cancer which was likely due to VHL mutations. Age distribution of familial lung cancer was unique in showing a wide peak extending from middle to old ages, which would be consistent with a combination of direct genetic effects and indirect influence on inheritance of smoking dependence.

Conclusions

The present review of age-specific familial risks and age-of-onset data from the literature may allow an interpretation that the familial and germline landscapes are reasonably harmonious for relatively early onset cancers but at higher ages no discrete peaks can be found which may implicate attenuated impact of high-risk genes and polygenic influence.
A new perspective for enhancing social and ecological systems coordination in ecological restoration
Authors: Zhou Guangjin , Gao Jixi , Zhang Riqi , Yang Zixiao , Zhang Siqi , Wang Lingqing , Su Yiming , Huan Yizhong , Liang Tao
Published: February 2025

Background

Ecosystem services (ESs) are fundamental to ensuring human well-being and sustainable development. However, the complex nonlinear relationships between ESs and social systems are still not fully recognized at present. Here, we used a comprehensive indicator framework, a coupling coordination degree (CCD) model, and a GeoDetector model to measure the CCD and development level of ESs and social systems in Sanmenxia City, Henan Province, China from 2000 to 2020, analyze the spatial patterns and temporal variations of their development, and quantify the influence of 15 factors on the spatial heterogeneity of their CCD.

Results

We observed that the increase of social system development level in Sanmenxia City was higher than that of ESs’ provisioning capacity. From 2000 to 2020, the ecosystem service index value of Sanmenxia City increased by about 25%, while the level of social system development increased by 118.9%. The coordination between ESs and social systems improved by 25%, indicating that their relationships were shifting from trade-offs to synergies. Lushi County (one of the six administrative regions of Sanmenxia City) had the highest level of CCD, but the overall coordination remained relatively weak in Sanmenxia City, and none of the six administrative regions achieved a high level of coordination. CCD was influenced by multiple interacting factors, with topography and land use patterns being the primary drivers.

Conclusions

Optimizing the spatial layout of ecological space, agricultural space, and urban space based on natural geographic patterns can be an effective way to improve CCD. Accordingly, we identified the impacts of potential barriers on sustainable development and provided multiple possible effective actions. Our findings deepen the knowledge and understanding of the “human-nature relationships”, which are of great significance in promoting the synergistic development of social and ecological systems.
Experiences of participation in an education and support group for carers of people with longer-term psychosis: a qualitative study
Authors: Millard Isabel , Billings Jo , Greenfield Philippa , Bailey Jackie , Fearon Dave , Whittle Henry J. , Killaspy Helen
Published: February 2025

Background

It is well-established that carers of people with psychosis require support given the stress, social isolation and health problems commonly associated with their caring role. However, interventions for carers are under-researched and underprovided. Psychoeducation and support groups can improve carers’ experiences of caregiving, but there is insufficient evidence to inform an optimal intervention. Furthermore, the limited existing literature tends to focus on carer groups provided within early intervention services. We designed and implemented an education and support group programme for carers of people with longer term psychosis. The group ran twice, online in 2021 and face-to-face in 2023. We conducted a qualitative service evaluation to explore participants’ experiences of participation in the group and inform its further refinement.

Methods

We conducted in-depth, semi-structured interviews before and after each group programme which explored carers’ experiences of caring and of group participation, in order to understand its impact, potential mechanisms of effect, and any helpful or challenging aspects. Facilitators also provided written reflective notes. Data were analysed using reflexive thematic analysis.

Results

Seventeen carers and four facilitators participated. The group programme received highly positive feedback. Four main themes were identified regarding its impact on the experience of caring: 1) isolated versus connected and supported; 2) disempowered versus empowered; 3) grief, guilt, worry versus acceptance; 4) unmet needs: the challenges associated with participants’ caring roles which were not addressed by group participation. The group’s mechanisms of effect included: building connections between carers, building carers’ connections with services, and providing psychoeducation that improved carers’ confidence and increased their empathy for their relative. Key components of the group’s design were: attendees having similar experiences of caring attendees receiving clear information about the group’s purpose and format, and facilitation by senior mental professionals who enabled discussion. The main area for improvement was to increase accessibility to carers from minority groups.

Conclusions

This study explored participants' experiences of a psychoeducation and support group for carers of people with longer-term psychosis and showed that it was largely acceptable and received positively by participants. The results may explain why recent trials of carer focussed interventions that have relied on digital contact were not effective. Further research is needed, including clinical trials, to investigate the clinical and cost effectiveness of face-to-face carer groups.
Indonesian traditional herbal drinks: diversity, processing, and health benefits
Authors: Estiasih Teti , Maligan Jaya Mahar , Witoyo Jatmiko Eko , Mu’alim Adilla Aisyah Hana , Ahmadi Kgs , Mahatmanto Tunjung , Zubaidah Elok
Published: February 2025

Indonesia has plant-based traditional medicine (herbal) that is hereditary and believed to be used for disease therapy and prevention. The well-known of this traditional medicine is jamu, which has a long history of making, and now, some have limitedly explored their benefits on health scientifically. Traditional herbal drinks are part of jamu and are usually consumed as beverages for leisure and refreshment; in addition, they are hereditary believed to have many health benefits. The health efficacy of these herbal drinks is still poorly explored scientifically. This review explores the diversity, preparation methods, and health benefits of the most popular Indonesian traditional herbal drinks, mainly in Java Island, including kunyit asam, beras kencur, sinom, wedang uwuh, wedang jahe, and wedang pokak. Combining a literature review with field observations, it highlights key bioactive compounds such as curcumin, gingerol, and brazilin, known for their antioxidant, anti-inflammatory, and antimicrobial properties. The study uniquely integrates traditional knowledge with insights into modern processing techniques, such as ultra-high temperature processing by small-scale enterprises, and examines their cultural and historical significance. By addressing the limited scientific exploration of these drinks’ health benefits, this paper bridges the gap between traditional practices and scientific validation, contributing to the global understanding of functional beverages. Modern adaptations, including ultra-high temperature processing by small-scale enterprises, have enabled wider distribution and commercialization of herbal drinks. However, challenges such as maintaining bioactive compound integrity and scaling production while preserving traditional authenticity remain critical.
Acute Venous Outflow Obstruction After Coil Embolization of Giant Cavernous Carotid Aneurysm: 2-Dimensional Operative Video
Authors: Falzon Andrew M. , Abdelghafar Ahmed , Jamasi Roshawn , Krings Timo
Published: February 2025

BACKGROUND AND IMPORTANCE:

Endovascular treatment of giant carotid cavernous aneurysms (GCCAs) may be associated with complications including rapid intrasaccular thrombosis, embolic ischemic stroke, and caroticocavernous fistula.

CLINICAL PRESENTATION:

A female in her 6th decade presented with a chronic, right partial abducens nerve palsy. Magnetic resononance angiography demonstrated a 25-mm right GCCA causing mass effect on the right cavernous sinus. Coil embolization of the aneurysm and parent vessel was performed after passing a balloon test occlusion. Final angiography demonstrated complete embolization of the aneurysm, however, absent ipsilateral cavernous sinus drainage, which was present previously. Intraprocedurally, the patient had ipsilateral proptosis and chemosis. Once extubated, urgent ophthalmology review documented preserved and symmetrical visual acuity with both pupils reactive to light. Intraocular pressure was 19-mm and 11-mm Hg in the right and left eye, respectively. The right eye had -2 abduction with otherwise intact extraocular movements. Acute management included a total of 16-mg IV dexamethasone on day 1, followed by a course of oral steroids and prophylactic low molecular weight heparin. Postprocedure computed tomography of the head demonstrated periorbital soft tissue edema and dilatation of the right superior ophthalmic vein, which peaked at 6 hours postprocedure. The patients' ocular findings and visual disturbances subsided within 36 hours postprocedure. The chronic partial abducens nerve palsy remained.

CONCLUSION:

Acute proptosis, chemosis, and visual disturbances may occur from mass effect on the cavernous sinus with venous outflow obstruction after GCCA embolization. This is thought to be secondary to increased mass effect from intrasaccular thrombosis and the large coil mass.
Mobile phones and their impact on the socioeconomic development of rural women in Peru
Authors: Vela Meléndez Lindon , Tobón Sergio , Llonto Caicedo Yefferson , Reynosa Navarro Enaidy
Published: February 2025

Background The study examines the impact of mobile phones on the socioeconomic development of rural women in Peru, using data from the National Household Survey from 2016 to 2022. Previous studies have highlighted the role of information and communication technologies (ICT) in empowering rural women and reducing the digital gender gap. Method A quantitative approach and a correlational design were applied. The Mincer equation adjusted with the Heckman method was used to estimate the effect of mobile phone use on the income of rural women, considering socioeconomic and demographic variables. The sample included between 1,436 and 1,568 rural Peruvian women per year. Results The results indicate a positive correlation between owning a personal mobile phone and the income of rural women in the period 2016-2019. In 2018, owning a mobile phone was associated with a 39.3% increase in income levels. In 2022, this effect was 49.9%. Conclusions It is concluded that the income of rural women in Peru is positively linked to the possession of a mobile phone, but also depends on factors such as years of education, work experience, marital status, household headship, and labor market participation. The findings support the implementation of public policies to reduce the digital gender gap and promote sustainable development.
Developing and evaluating human-centered design solutions for enhancing maternal health service utilization among vulnerable pregnant women in Oromia, Ethiopia: Study protocol for a quasi-experimental study
Authors: Kang Bee-Ah , Tamene Habtamu , Lakew Yihunie , Stephens Daryl , Rimal Rajiv
Published: February 2025

Background Disproportionate uptake of and access to maternal and child health services remain significant challenges across and within countries. Differing geographic, economic, environmental, and social factors contribute to varying degrees of vulnerabilities among individuals, which manifest as disparities in maternal and newborn health outcomes. Designing solutions according to need is vital to improve maternal and child health outcomes. In this paper, we describe our study protocol on developing and evaluating the effectiveness of human-centered design (HCD) solutions to improve maternal health service uptake among vulnerable pregnant women in rural areas of Ethiopia. Methods The study has two distinct phases. In Phase 1, HCD solutions were developed through co-design workshops with vulnerable pregnant women and key stakeholders. Final solutions included home visit education, audio programs promoting couple discussion, and print materials, implemented in collaboration with community health workers and health officers. A community-based, quasi-experimental, mixed-method study design was used to assess differences between intervention and control arms. A panel sample was enrolled after screening for pregnancy and vulnerability level and surveyed at baseline and midline in Phase 1. Phase 2 adopts an identical design approach with a focus on refining Phase 1 solutions. Newly recruited pregnant women will receive refined solutions for six months, which will be evaluated using post-only end-line surveys and in-depth interviews. Conclusions and Implications Our sequential approach to evaluating initial solutions, which in turn will inform the enhancement of solutions, will provide practical insights into how solutions are accepted among vulnerable women and how they can be better integrated into women’s lives and health systems. This will inform equity-focused practice and policies targeting populations experiencing greater barriers to accessing care and provide insights into system strengthening in rural areas. Our findings will be disseminated to the Ethiopian Ministry of Health and its partners to inform large-scale implementation at the national level.
La investigación sobre ética periodística en España: ¿moda académica o conciencia científica?
Authors: Polledo Zulueta Yenisley
Published: February 2025

En los últimos años la comunidad académica española ha sido testigo de un repunte de la producción científica sobre ética de la comunicación en el ámbito periodístico. El objetivo de este artículo es conocer si el interés por investigar esta temática es resultado de una moda académica o de una genuina convicción sobre la  importancia de desarrollar estos estudios en el actual contexto mediático español. Para abordar este asunto, analizamos el criterio de once investigadores, con experiencia en la dirección de proyectos y grupos de investigación, dedicados al estudio de la ética de la comunicación mediática en el ámbito de las universidades españolas. A partir de la aplicación de entrevistas semiestructuradas, indagamos sobre la pertinencia de la ética periodística y sobre los elementos que activan la voluntad de investigarla. En este proceso, además, nos centramos en localizar y analizar las sincronías argumentales presentes en los discursos registrados. En los resultados se identifican criterios que sitúan a la conciencia científica como soporte de la indagación sobre ética de la comunicación mediática en el contexto español.
A Psychoeducational Intervention for Breast Cancer Screening Methods and Healthy Lifestyles for University Students and Their Families
Authors: García-Rosas Yasmin , Juárez García Dehisy Marisol , Sanchez-Jauregui Teresa de Jesús , Téllez Arnoldo
Published: February 2025

Background. In Mexico, cancer is a public health problem that represents the second leading cause of death among those aged 20 years, three out of ten women with cancer suffer from breast cancer, and most women are of reproductive age at the time of diagnosis, which affects the socioeconomic well-being of families. Objective: This study was to evaluate the effects of a psychoeducational intervention on breast cancer screening methods beliefs and healthy lifestyle in university women and their families. Materials and methods: A post-test pretest design was used, in which 42 university students participated who received a psychoeducational intervention of 3 sessions on methods of breast cancer detection and healthy due style and who in turn shared the information with their relatives (n = 28). Results: significant differences were found in the group of university students in perceived seriousness (z=-1.95, p=.047, d= 0.48), perceived self-efficacy (z=-3.62, p=.001, d= 2.5) and physical activity (z=-3.18, p=.001, d=1.8). In the relatives there were also significant differences in the posttest in susceptibility (z=-2.31, p=.021, d= 0.82), perceived seriousness (z =-2.30, p=.021, d= 0.98), perceived self-efficacy (z = -2.37, p=.018, d=1.51) and motivation for health (z = -2.30, p=.021, d=1.10). Conclusion: Psychoeducational intervention can improve beliefs about cancer and its screening methods in college students and their families, so it can be used as a strategy to extend the promotion of breast screening methods and healthy lifestyle.
Desafíos para el derecho generados por la economía digital
Authors: Restrepo Medina Manuel Alberto
Published: February 2025

Luego de hacer algunas consideraciones sobre las principales características de la economía digital, que permiten darle contexto a la problemática abordada, el presente capítulo se ocupa de identificar las principales implicaciones que la misma está generando en el derecho laboral, el derecho tributario y el derecho comercial, para cuyo efecto se ha realizado una revisión de la bibliografía disponible sobre la materia, empleando como descriptores de búsqueda los términos “economía digital” y “derecho y economía digital”.
Aproximación a los elementos disruptivos en la industria 4.0 y nuevas realidades en el futuro del trabajo
Authors: Camacho-Ramírez Adriana , Nieto Vargas Lorena
Published: February 2025

La metodología utilizada en la investigación que sustenta este capítulo es la cualitativa con enfoque dogmático en fuentes doctrinales que permitan afrontar los desafíos de la cuarta revolución industrial en el futuro del trabajo.
El impacto de la cuarta revolución industrial y las nuevas tecnologías en el mundo del trabajo
Authors: Amaya Ballesteros María Alejandra
Published: February 2025

Por lo tanto, en este capítulo se pretende identificar el impacto, y las consecuencias positivas y negativas, que genera la aparición de nuevas tecnologías en las relaciones laborales a través de lo que se concibe como la cuarta revolución industrial, definida por Schwab como la unión de tecnologías que atenúa los límites entre las esferas de lo físico, digital y biológico.1 En virtud de lo anterior, se busca describir en qué consisten algunas de las nuevas tecnologías, evaluar las posibles ventajas y desventajas de la implementación de estas en el mundo laboral; más específicamente, se hace referencia a los impactos y avances que generaría la incorporación de nuevas tecnologías en las relaciones laborales en Colombia junto con los retos que se derivan de dicha aplicación para el orden jurídico.
El capítulo se desarrolla a través del método cualitativo descriptivo, debido a que procede ala interpretación de ciertos conceptos, así como el análisis teórico y práctico de dicha conceptualización, abarcando la descripción de tecnologías emergentes, como la inteligencia artificial, la robotización, la impresión 3D y el llamado internet de las cosas, aplicadas, desde una perspectiva jurídica, al mundo laboral colombiano. De igual manera, se hace una aproximación a la evolución de este tema en las medidas del Gobierno de Colombia y las iniciativas legislativas por regularlo jurídicamente. Enseguida, se tratan las consecuencias de la incorporación de estas nuevas tecnologías en las relaciones laborales. Por último, se hablará sobre los retos para la inclusión de tecnologías emergentes en el trabajo.
Seguridad social de los nómadas digitales con nacionalidad colombiana
Authors: Pérez Mancipe Paola Edith
Published: February 2025

Este capítulo indagará la forma de regulación existente en materia de seguridad social en Colombia frente al trabajador que recibe la denominación de nómada digital. Lo anterior, partiendo de los cambios que han surgido con el uso de las nuevas tecnologías en aplicación de trabajo remoto y con el inicio del confinamiento decretado por la Organización Mundial de la Salud con ocasión a la emergencia sanitaria debido a la pandemia por la covid-19). A partir de lo anterior, los cambios generados por la pandemia nos han obligado, en materia laboral, a adaptarnos a nuevas formas de trabajar y de vivir, circunstancias que generan para el legislador retos en torno a una actualización normativa con el objetivo de crear herramientas que brinden a los nómadas digitales seguridad jurídica a través de una regulación segura.
Por consiguiente, este capítulo se desarrolla en el marco de un objetivo principal que consiste en determinar la regulación existente en materia de seguridad social para nómadas digitales; como objetivos segundarios, busca evaluar si es importante que los nómadas digitales cuenten con cobertura en seguridad social, analizar si ser nómada digital es una figura viable para el Sistema General de Seguridad Social y verificar si es eficiente expedir normatividad que regule la cobertura de riesgos laborales para nómadas digitales en Colombia.