bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Materials from Systematic Establishment of Robustness and Standards in Patient-Derived Xenograft Experiments and Analysis
Authors: Evrard Yvonne A. , Srivastava Anuj , Randjelovic Jelena , Doroshow James H. , Dean Dennis A. , Morris Jeffrey S. , Chuang Jeffrey H.
Published: April 2023

The supplementary file contains additional methods, analyses, and details of workflows as referenced in the manuscript, including all supplementary figures and tables. A full table of contents and descriptions are provided within.
Figure S5 from Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization
Authors: So Jae Young , Skrypek Nicolas , Yang Howard H. , Merchant Anand S. , Nelson George W. , Chen Wei-Dong , Ishii Hiroki , Chen Jennifer M. , Hu Gangqing , Achyut Bhagelu R. , Yoon Esther C. , Han Liying , Huang Chuanshu , Cam Margaret C. , Zhao Keji , Lee Maxwell P. , Yang Li
Published: April 2023

Induction of DNMT3B by inflammatory molecules
Figure S2 from Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization
Authors: So Jae Young , Skrypek Nicolas , Yang Howard H. , Merchant Anand S. , Nelson George W. , Chen Wei-Dong , Ishii Hiroki , Chen Jennifer M. , Hu Gangqing , Achyut Bhagelu R. , Yoon Esther C. , Han Liying , Huang Chuanshu , Cam Margaret C. , Zhao Keji , Lee Maxwell P. , Yang Li
Published: April 2023

Genome-wide sequence datasets validation
Supplemental figure 4 from Melanoma-Secreted Lysosomes Trigger Monocyte-Derived Dendritic Cell Apoptosis and Limit Cancer Immunotherapy
Authors: Santana-Magal Nadine , Farhat-Younis Leen , Gutwillig Amit , Gleiberman Annette , Rasoulouniriana Diana , Tal Lior , Netanely Dvir , Shamir Ron , Blau Rachel , Feinmesser Meora , Zlotnik Oran , Gutman Haim , Linde Ian L. , Reticker-Flynn Nathan E. , Rider Peleg , Carmi Yaron
Published: April 2023

Melanoma tumor cells secrete lysosomes which are taken up by dendritic cells
Supplementary Table S1 from Resistance to MAPK Inhibitors in Melanoma Involves Activation of the IGF1R–MEK5–Erk5 Pathway
Authors: Benito-Jardón Lucía , Díaz-Martínez Marta , Arellano-Sánchez Nohemi , Vaquero-Morales Paloma , Esparís-Ogando Azucena , Teixidó Joaquin
Published: April 2023

siRNAs and oligonucleotides used in qPCR experiments
Supplemental figure 2 from Melanoma-Secreted Lysosomes Trigger Monocyte-Derived Dendritic Cell Apoptosis and Limit Cancer Immunotherapy
Authors: Santana-Magal Nadine , Farhat-Younis Leen , Gutwillig Amit , Gleiberman Annette , Rasoulouniriana Diana , Tal Lior , Netanely Dvir , Shamir Ron , Blau Rachel , Feinmesser Meora , Zlotnik Oran , Gutman Haim , Linde Ian L. , Reticker-Flynn Nathan E. , Rider Peleg , Carmi Yaron
Published: April 2023

Cell numbers of multiple immune cell substes, and mainly dendritic cells, are decreased over time in melanoma tumors.
Supplementary Figure S4 from Resistance to MAPK Inhibitors in Melanoma Involves Activation of the IGF1R–MEK5–Erk5 Pathway
Authors: Benito-Jardón Lucía , Díaz-Martínez Marta , Arellano-Sánchez Nohemi , Vaquero-Morales Paloma , Esparís-Ogando Azucena , Teixidó Joaquin
Published: April 2023

Effect of linsitinib in cell resistance to SCH and in activation of the PI3K-Akt pathway
Supplementary Figure S1 from Resistance to MAPK Inhibitors in Melanoma Involves Activation of the IGF1R–MEK5–Erk5 Pathway
Authors: Benito-Jardón Lucía , Díaz-Martínez Marta , Arellano-Sánchez Nohemi , Vaquero-Morales Paloma , Esparís-Ogando Azucena , Teixidó Joaquin
Published: April 2023

Analysis of growth rate, MAPK activation, PTEN and Cyclin E1 expression in SCH- and double-resistant A375 and SK-Mel 28 melanoma cells
Supplementary Data from Resistance to MAPK Inhibitors in Melanoma Involves Activation of the IGF1R–MEK5–Erk5 Pathway
Authors: Benito-Jardón Lucía , Díaz-Martínez Marta , Arellano-Sánchez Nohemi , Vaquero-Morales Paloma , Esparís-Ogando Azucena , Teixidó Joaquin
Published: April 2023

Supplementary materials and methods and supplementary figure legends
Supplementary Table 1 from Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan–Targeting Antibodies without the Need for Immune Effector Cells or Complement
Authors: Vankemmelbeke Mireille , McIntosh Richard S. , Chua Jia Xin , Kirk Thomas , Daniels Ian , Patsalidou Marilena , Moss Robert , Parsons Tina , Scott David , Harris Gemma , Ramage Judith M. , Spendlove Ian , Durrant Lindy G.
Published: April 2023

Overview of the kinetic binding parameters of the parental 88 mAbs
Supplementary Figure 4 from Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan–Targeting Antibodies without the Need for Immune Effector Cells or Complement
Authors: Vankemmelbeke Mireille , McIntosh Richard S. , Chua Jia Xin , Kirk Thomas , Daniels Ian , Patsalidou Marilena , Moss Robert , Parsons Tina , Scott David , Harris Gemma , Ramage Judith M. , Spendlove Ian , Durrant Lindy G.
Published: April 2023

Negligible direct cell killing ability by i129G1 on low to moderate binding cancer cell lines compared to the high-binding COLO205
Figure S5 from HER2 CAR-T Cells Eradicate Uveal Melanoma and T-cell Therapy–Resistant Human Melanoma in IL2 Transgenic NOD/SCID IL2 Receptor Knockout Mice
Authors: Forsberg Elin M.V. , Lindberg Mattias F. , Jespersen Henrik , Alsén Samuel , Bagge Roger Olofsson , Donia Marco , Svane Inge Marie , Nilsson Ola , Ny Lars , Nilsson Lisa M. , Nilsson Jonas A.
Published: April 2023

IHC and flow cytometry detection of T and NK-cells in PDX models transplanted with HER2 CAR-T cells
Supplementary Figure 3 from Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan–Targeting Antibodies without the Need for Immune Effector Cells or Complement
Authors: Vankemmelbeke Mireille , McIntosh Richard S. , Chua Jia Xin , Kirk Thomas , Daniels Ian , Patsalidou Marilena , Moss Robert , Parsons Tina , Scott David , Harris Gemma , Ramage Judith M. , Spendlove Ian , Durrant Lindy G.
Published: April 2023

Sensorgrams of real-time glycan-HSA binding by parental and improved mAb constructs
Figure S3 from HER2 CAR-T Cells Eradicate Uveal Melanoma and T-cell Therapy–Resistant Human Melanoma in IL2 Transgenic NOD/SCID IL2 Receptor Knockout Mice
Authors: Forsberg Elin M.V. , Lindberg Mattias F. , Jespersen Henrik , Alsén Samuel , Bagge Roger Olofsson , Donia Marco , Svane Inge Marie , Nilsson Ola , Ny Lars , Nilsson Lisa M. , Nilsson Jonas A.
Published: April 2023

Comparison of T-cell immunity of TILs and HER2 CAR-T cells in PDX models of melanoma
Supplementary Figure 1 from Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan–Targeting Antibodies without the Need for Immune Effector Cells or Complement
Authors: Vankemmelbeke Mireille , McIntosh Richard S. , Chua Jia Xin , Kirk Thomas , Daniels Ian , Patsalidou Marilena , Moss Robert , Parsons Tina , Scott David , Harris Gemma , Ramage Judith M. , Spendlove Ian , Durrant Lindy G.
Published: April 2023

Cartoon representation of the key Fc-engineered constructs
Supplementary Methods from NRAS Status Determines Sensitivity to SHP2 Inhibitor Combination Therapies Targeting the RAS–MAPK Pathway in Neuroblastoma
Authors: Valencia-Sama Ivette , Ladumor Yagnesh , Kee Lynn , Adderley Teresa , Christopher Gabriella , Robinson Claire M. , Kano Yoshihito , Ohh Michael , Irwin Meredith S.
Published: April 2023

Includes supplementary methodology for cell culture, chemicals, plasmids and transfections, GTP pulldown and immunoblotting analyses, and antibodies used for study.
Figures S1-S3; Suppl Methods from ATM Loss Confers Greater Sensitivity to ATR Inhibition Than PARP Inhibition in Prostate Cancer
Authors: Rafiei Shahrzad , Fitzpatrick Kenyon , Liu David , Cai Mu-Yan , Elmarakeby Haitham A. , Park Jihye , Ricker Cora , Kochupurakkal Bose S. , Choudhury Atish D. , Hahn William C. , Balk Steven P. , Hwang Justin H. , Van Allen Eliezer M. , Mouw Kent W.
Published: April 2023

Immunofluorescence and IR survival data; additional methods
Table S3 from Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer
Authors: Wang Shidan , Rong Ruichen , Yang Donghan M. , Fujimoto Junya , Yan Shirley , Cai Ling , Yang Lin , Luo Danni , Behrens Carmen , Parra Edwin R. , Yao Bo , Xu Lin , Wang Tao , Zhan Xiaowei , Wistuba Ignacio I. , Minna John , Xie Yang , Xiao Guanghua
Published: April 2023

Supplemental Table S3 Variable coefficients in the image-feature based risk prediction model.
Figure S8 from Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer
Authors: Wang Shidan , Rong Ruichen , Yang Donghan M. , Fujimoto Junya , Yan Shirley , Cai Ling , Yang Lin , Luo Danni , Behrens Carmen , Parra Edwin R. , Yao Bo , Xu Lin , Wang Tao , Zhan Xiaowei , Wistuba Ignacio I. , Minna John , Xie Yang , Xiao Guanghua
Published: April 2023

Supplemental Figure S8 Volcano plots of gene set enrichment analysis results correlating mRNA expression level with stroma nuclei density and karyorrhexis density, respectively.
Supplementary Figure 2 from Hispanic/Latino Patients with Gastric Adenocarcinoma Have Distinct Molecular Profiles Including a High Rate of Germline CDH1 Variants
Authors: Wang Sam C. , Yeu Yunku , Hammer Suntrea T.G. , Xiao Shu , Zhu Min , Hong Changjin , Clemenceau Jean R. , Yoon Lynn Y. , Nassour Ibrahim , Shen Jeanne , Agarwal Deepak , Reznik Scott I. , Mansour John C. , Yopp Adam C. , Zhu Hao , Hwang Tae Hyun , Porembka Matthew R.
Published: April 2023

a. The Cancer Genome Atlas algorithm to categorize gastric cancer into four molecular subtypes: Epstein-Barr virus infected (EBV, red), microsatellite instability (MSI, blue), chromosomal instability (CIN, purple), and genomically stable (GS, green). SCNA = somatic copy number alterations. b. MSIsensor score. Whole-exome sequence data from each Hispanic/Latino cancer sample were analyzed with MSIsenor. Gray bar denotes total mutation burden per megabase. Yellow bar denotes calculated MSIsensor score. Samples with score {greater than or equal to} 10 were considered to be microsatellite unstable.
Figure S4 from A Versatile ES Cell–Based Melanoma Mouse Modeling Platform
Authors: Bok Ilah , Vera Olga , Xu Xiaonan , Jasani Neel , Nakamura Koji , Reff Jordan , Nenci Arianna , Gonzalez Jose G. , Karreth Florian A.
Published: April 2023

This Figure shows the effect of Dox on melanomas as well as the growth of individual shPten tumors upon Dox withdrawal.
Supplementary Figure 1 from Hispanic/Latino Patients with Gastric Adenocarcinoma Have Distinct Molecular Profiles Including a High Rate of Germline CDH1 Variants
Authors: Wang Sam C. , Yeu Yunku , Hammer Suntrea T.G. , Xiao Shu , Zhu Min , Hong Changjin , Clemenceau Jean R. , Yoon Lynn Y. , Nassour Ibrahim , Shen Jeanne , Agarwal Deepak , Reznik Scott I. , Mansour John C. , Yopp Adam C. , Zhu Hao , Hwang Tae Hyun , Porembka Matthew R.
Published: April 2023

a. Age at the time of diagnosis of Hispanic/Latino (Hs/L) patients from this study, and of Asian and White patients analyzed by The Cancer Genome Atlas (TCGA). Horizontal lines, medians; boxes, interquartile ranges; whiskers, maximum and minimum values. P < 0.001. b. Second view of the principal component analysis of whole-exome sequencing data, as analyzed by Locating Ancestry from SEquence Reads to define patient ancestry of Asian and White patients analyzed by the TCGA and Hispanic/Latino patients from this study, as compared to reference from the Human Genome Diversity Project (HGDP).
Supplementary Tables 1-5 from CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human Lung and Colorectal Cancer Cells
Authors: Rogers Rebecca F. , Walton Michael I. , Cherry Daniel L. , Collins Ian , Clarke Paul A. , Garrett Michelle D. , Workman Paul
Published: April 2023

Supplementary Tables - ST1: Significant siRNA hits identified from the large-scale synthetic lethal siRNA screen combined with SRA737 in A549 cells. ST2: Significant siRNA hits identified from the large-scale synthetic lethal siRNA screen combined with SRA737 in SW620 cells. ST3: CI (exclusive) values for combination treatment with SRA737 plus either aphidicolin, CD437 or gemcitabine in a panel of NSCLC and colorectal cancer cell lines. ST4: Key genetic aberrations in the total panel of NSCLC and colorectal cancer cell lines used. ST5: GI50 values for SRA737, aphidicolin, CD437 and gemcitabine as single agents in the total panel of NSCLC and colorectal cancer cell lines used.
Supplementary Data from Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death
Authors: Ommer Johannes , Selfe Joanna L. , Wachtel Marco , O'Brien Eleanor M. , Laubscher Dominik , Roemmele Michaela , Kasper Stephanie , Delattre Olivier , Surdez Didier , Petts Gemma , Kelsey Anna , Shipley Janet , Schäfer Beat W.
Published: April 2023

Supplemental Figure S1 - S11
Supplementary Data from Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death
Authors: Ommer Johannes , Selfe Joanna L. , Wachtel Marco , O'Brien Eleanor M. , Laubscher Dominik , Roemmele Michaela , Kasper Stephanie , Delattre Olivier , Surdez Didier , Petts Gemma , Kelsey Anna , Shipley Janet , Schäfer Beat W.
Published: April 2023

Supplemental Materials and Methods
Supplementary tables from HIF2-Induced Long Noncoding RNA RAB11B-AS1 Promotes Hypoxia-Mediated Angiogenesis and Breast Cancer Metastasis
Authors: Niu Yanling , Bao Lei , Chen Yan , Wang Chenliang , Luo Maowu , Zhang Bo , Zhou Mi , Wang Jennifer E. , Fang Yisheng V. , Kumar Ashwani , Xing Chao , Wang Yingfei , Luo Weibo
Published: April 2023

Table S1-3. Supplementary Table S1. Oligonucleotide sequence used for qPCR primers. Supplementary Table S2. Oligonucleotide sequence used for HIF-1b sgRNA and RAB11B-AS1 shRNA, HRE, and RACE cloning primers. Supplementary Table S3. Gene ontology analysis of LncRAB11B-AS1-induced genes in hypoxic MDA-MB-231 cells.
Supplementary Tables S1-S5 from ATM Paradoxically Promotes Oncogenic Transformation via Transcriptional Reprogramming
Authors: Liu Xinjian , Hu Mengjie , Liu Pei , Jiao Meng , Zhou Min , Lee Andrew K. , Li Fang , Li Chuan-Yuan
Published: April 2023

Supplementary Tables with details info on cells, antibodies, PCR primers, human gene expression datasets, and GSEA pathways.
Supplementary Figure S7 from ATM Paradoxically Promotes Oncogenic Transformation via Transcriptional Reprogramming
Authors: Liu Xinjian , Hu Mengjie , Liu Pei , Jiao Meng , Zhou Min , Lee Andrew K. , Li Fang , Li Chuan-Yuan
Published: April 2023

Analysis of ATM mRNA expression in matched normal and cancer tissues from human patients.
Figure S4 from ATM Paradoxically Promotes Oncogenic Transformation via Transcriptional Reprogramming
Authors: Liu Xinjian , Hu Mengjie , Liu Pei , Jiao Meng , Zhou Min , Lee Andrew K. , Li Fang , Li Chuan-Yuan
Published: April 2023

Q-RT-PCR confirmation of select gene expression in control and oncogene transformed normal and ATM-deficient cells.
Figure S6 from LIN9 and NEK2 Are Core Regulators of Mitotic Fidelity That Can Be Therapeutically Targeted to Overcome Taxane Resistance
Authors: Roberts Melyssa S. , Sahni Jennifer M. , Schrock Morgan S. , Piemonte Katrina M. , Weber-Bonk Kristen L. , Seachrist Darcie D. , Avril Stefanie , Anstine Lindsey J. , Singh Salendra , Sizemore Steven T. , Varadan Vinay , Summers Matthew K. , Keri Ruth A.
Published: April 2023

Pharmacological inhibition of NEK2 potentiates taxane sensitivity in vivo.
Figure S1 from ATM Paradoxically Promotes Oncogenic Transformation via Transcriptional Reprogramming
Authors: Liu Xinjian , Hu Mengjie , Liu Pei , Jiao Meng , Zhou Min , Lee Andrew K. , Li Fang , Li Chuan-Yuan
Published: April 2023

Western blot analysis of exogenous and endogenous expression.
Supplementary Table S3 from The Deubiquitinase USP38 Promotes NHEJ Repair through Regulation of HDAC1 Activity and Regulates Cancer Cell Response to Genotoxic Insults
Authors: Yang Yongfeng , Yang Chuanzhen , Li Tingting , Yu Shuyu , Gan Tingting , Hu Jiazhi , Cui Jun , Zheng Xiaofeng
Published: April 2023

Supplementary Table S3
Supplementary Table S2 from The Deubiquitinase USP38 Promotes NHEJ Repair through Regulation of HDAC1 Activity and Regulates Cancer Cell Response to Genotoxic Insults
Authors: Yang Yongfeng , Yang Chuanzhen , Li Tingting , Yu Shuyu , Gan Tingting , Hu Jiazhi , Cui Jun , Zheng Xiaofeng
Published: April 2023

Supplementary Table S2
Figure S1 from LIN9 and NEK2 Are Core Regulators of Mitotic Fidelity That Can Be Therapeutically Targeted to Overcome Taxane Resistance
Authors: Roberts Melyssa S. , Sahni Jennifer M. , Schrock Morgan S. , Piemonte Katrina M. , Weber-Bonk Kristen L. , Seachrist Darcie D. , Avril Stefanie , Anstine Lindsey J. , Singh Salendra , Sizemore Steven T. , Varadan Vinay , Summers Matthew K. , Keri Ruth A.
Published: April 2023

LIN9 silencing restores docetaxel sensitivity, unlike silencing of LIN37, another member of the MuvB complex.
Table S4: Gene Ontology analysis of LUAD tumors from A Division of Labor between YAP and TAZ in Non–Small Cell Lung Cancer
Authors: Shreberk-Shaked Michal , Dassa Bareket , Sinha Sanju , Di Agostino Silvia , Azuri Ido , Mukherjee Saptaparna , Aylon Yael , Blandino Giovanni , Ruppin Eytan , Oren Moshe
Published: April 2023

Gene Ontology results of either the YAP-correlated or TAZ-correlated genes in LUAD TCGA, determined by Metascape.
Table S3: Gene Ontology analysis of H1299 RNA-seq from A Division of Labor between YAP and TAZ in Non–Small Cell Lung Cancer
Authors: Shreberk-Shaked Michal , Dassa Bareket , Sinha Sanju , Di Agostino Silvia , Azuri Ido , Mukherjee Saptaparna , Aylon Yael , Blandino Giovanni , Ruppin Eytan , Oren Moshe
Published: April 2023

Gene ontology results of either YAP-regulated or TAZ-regulated genes from H1299 RNA-seq analysis, determined by Metascape.
Supplementary Data from EpCAM Signaling Promotes Tumor Progression and Protein Stability of PD-L1 through the EGFR Pathway
Authors: Chen Hao-Nien , Liang Kang-Hao , Lai Jun-Kai , Lan Chun-Hsin , Liao Mei-Ying , Hung Shao-Hsi , Chuang Yi-Ting , Chen Kai-Chi , Tsuei William Wei-Fu , Wu Han-Chung
Published: April 2023

Figure S1-S8
Supplementary Figures file from A Division of Labor between YAP and TAZ in Non–Small Cell Lung Cancer
Authors: Shreberk-Shaked Michal , Dassa Bareket , Sinha Sanju , Di Agostino Silvia , Azuri Ido , Mukherjee Saptaparna , Aylon Yael , Blandino Giovanni , Ruppin Eytan , Oren Moshe
Published: April 2023

Supplementary Figures
Supplementary Tables from Genome-Wide Association Study Data Reveal Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductal Adenocarcinoma Risk
Authors: Yuan Fangcheng , Hung Rayjean J. , Walsh Naomi , Zhang Han , Platz Elizabeth A. , Wheeler William , Song Lei , Arslan Alan A. , Beane Freeman Laura E. , Bracci Paige , Canzian Federico , Du Mengmeng , Gallinger Steven , Giles Graham G. , Goodman Phyllis J. , Kooperberg Charles , Le Marchand Loic , Neale Rachel E. , Rosendahl Jonas , Scelo Ghislaine , Shu Xiao-Ou , Visvanathan Kala , White Emily , Zheng Wei , Albanes Demetrius , Amiano Pilar , Andreotti Gabriella , Babic Ana , Bamlet William R. , Berndt Sonja I. , Brennan Paul , Bueno-de-Mesquita Bas , Buring Julie E. , Campbell Peter T. , Chanock Stephen J. , Fuchs Charles S. , Gaziano J. Michael , Goggins Michael G. , Hackert Thilo , Hartge Patricia , Hassan Manal M. , Holly Elizabeth A. , Hoover Robert N. , Katzke Verena , Kirsten Holger , Kurtz Robert C. , Lee I-Min , Malats Nuria , Milne Roger L. , Murphy Neil , Ng Kimmie , Oberg Ann L. , Porta Miquel , Rabe Kari G. , Real Francisco X. , Rothman Nathaniel , Sesso Howard D. , Silverman Debra T. , Thompson Ian M. , Wactawski-Wende Jean , Wang Xiaoliang , Wentzensen Nicolas , Wilkens Lynne R. , Yu Herbert , Zeleniuch-Jacquotte Anne , Shi Jianxin , Duell Eric J. , Amundadottir Laufey T. , Li Donghui , Petersen Gloria M. , Wolpin Brian M. , Risch Harvey A. , Yu Kai , Klein Alison P. , Stolzenberg-Solomon Rachael
Published: April 2023

The file contains supplementary tables S1, S2, S3, S4, S5, S6, and S7.
Table S3 from Cancer-Associated Point Mutations in the DLC1 Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased Function
Authors: Wang Dunrui , Qian Xiaolan , Sanchez-Solana Beatriz , Tripathi Brajendra K. , Durkin Marian E. , Lowy Douglas R.
Published: April 2023

Co-occurrence of Rho-GAP gene and RHOA/C all type mutations
Figure S6 from Cancer-Associated Point Mutations in the DLC1 Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased Function
Authors: Wang Dunrui , Qian Xiaolan , Sanchez-Solana Beatriz , Tripathi Brajendra K. , Durkin Marian E. , Lowy Douglas R.
Published: April 2023

DLC1 Rho-GAP mutants reduce Rho-GAP activity
Supplementary Materials from Association of the Age at Menarche with Site-Specific Cancer Risks in Pooled Data from Nine Cohorts
Authors: Fuhrman Barbara J. , Moore Steven C. , Byrne Celia , Makhoul Issam , Kitahara Cari M. , Berrington de González Amy , Linet Martha S. , Weiderpass Elisabete , Adami Hans-Olov , Freedman Neal D. , Liao Linda M. , Matthews Charles E. , Stolzenberg-Solomon Rachael Z. , Gaudet Mia M. , Patel Alpa V. , Lee I-Min , Buring Julie E. , Wolk Alicja , Larsson Susanna C. , Prizment Anna E. , Robien Kim , Spriggs Michael , Check David P. , Murphy Neil , Gunter Marc J. , Van Dusen Harold L. , Ziegler Regina G. , Hoover Robert N.
Published: April 2023

Tables 1-17, Figure S1, and acknowledgements.
Supplementary Table 1 from Structural Optimization and Enhanced Prodrug-Mediated Delivery Overcomes Camptothecin Resistance in High-Risk Solid Tumors
Authors: Nguyen Ferro , Guan Peng , Guerrero David T. , Kolla Venkatadri , Naraparaju Koumudi , Perry Lauren M. , Soberman Danielle , Pressly Benjamin B. , Alferiev Ivan S. , Chorny Michael , Brodeur Garrett M.
Published: April 2023

SN22 and SN38 pharmacokinetics
Supplementary Figure 2 from Structural Optimization and Enhanced Prodrug-Mediated Delivery Overcomes Camptothecin Resistance in High-Risk Solid Tumors
Authors: Nguyen Ferro , Guan Peng , Guerrero David T. , Kolla Venkatadri , Naraparaju Koumudi , Perry Lauren M. , Soberman Danielle , Pressly Benjamin B. , Alferiev Ivan S. , Chorny Michael , Brodeur Garrett M.
Published: April 2023

Liver function tests
Supplementary Data from Extracellular Vesicle–Derived miR-124 Resolves Radiation-Induced Brain Injury
Authors: Leavitt Ron J. , Acharya Munjal M. , Baulch Janet E. , Limoli Charles L.
Published: April 2023

Supplemental Figures and Tables
Table S1 from Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma
Authors: Qazi Maleeha A. , Vora Parvez , Venugopal Chitra , Adams Jarrett , Singh Mohini , Hu Amy , Gorelik Maryna , Subapanditha Minomi K. , Savage Neil , Yang Jiahe , Chokshi Chirayu , London Max , Gont Alexander , Bobrowski David , Grinshtein Natalie , Brown Kevin R. , Murty Naresh K. , Nilvebrant Johan , Kaplan David , Moffat Jason , Sidhu Sachdev , Singh Sheila K.
Published: April 2023

Patient demographics.
Figure S6 from Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma
Authors: Qazi Maleeha A. , Vora Parvez , Venugopal Chitra , Adams Jarrett , Singh Mohini , Hu Amy , Gorelik Maryna , Subapanditha Minomi K. , Savage Neil , Yang Jiahe , Chokshi Chirayu , London Max , Gont Alexander , Bobrowski David , Grinshtein Natalie , Brown Kevin R. , Murty Naresh K. , Nilvebrant Johan , Kaplan David , Moffat Jason , Sidhu Sachdev , Singh Sheila K.
Published: April 2023

EphA2/A3 BsAb also targets EphA2+/EphA3- and EphA2-/EphA3+ cell populations, does not affect cell cycle or apoptosis, and leads to increased expression of GFAP and MAP2.
Figure S5 from Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma
Authors: Qazi Maleeha A. , Vora Parvez , Venugopal Chitra , Adams Jarrett , Singh Mohini , Hu Amy , Gorelik Maryna , Subapanditha Minomi K. , Savage Neil , Yang Jiahe , Chokshi Chirayu , London Max , Gont Alexander , Bobrowski David , Grinshtein Natalie , Brown Kevin R. , Murty Naresh K. , Nilvebrant Johan , Kaplan David , Moffat Jason , Sidhu Sachdev , Singh Sheila K.
Published: April 2023

Recurrent GBMs express low levels of ephrinA1/A5 ligands, and treatment with EphA2.A3 BsAb leads to EphA2 phosphorylation but does not alter other EphR expression.
Figure S4 from Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma
Authors: Qazi Maleeha A. , Vora Parvez , Venugopal Chitra , Adams Jarrett , Singh Mohini , Hu Amy , Gorelik Maryna , Subapanditha Minomi K. , Savage Neil , Yang Jiahe , Chokshi Chirayu , London Max , Gont Alexander , Bobrowski David , Grinshtein Natalie , Brown Kevin R. , Murty Naresh K. , Nilvebrant Johan , Kaplan David , Moffat Jason , Sidhu Sachdev , Singh Sheila K.
Published: April 2023

High affinity EphA2/A3 BsAb is internalized, leading to decreased expression of EphA2 and EphA3.
TableS5 from FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy
Authors: Manfrini Nicola , Mancino Marilena , Miluzio Annarita , Oliveto Stefania , Balestra Matteo , Calamita Piera , Alfieri Roberta , Rossi Riccardo L. , Sassoè-Pognetto Marco , Salio Chiara , Cuomo Alessandro , Bonaldi Tiziana , Manfredi Marcello , Marengo Emilio , Ranzato Elia , Martinotti Simona , Cittaro Davide , Tonon Giovanni , Biffo Stefano
Published: April 2023

RNAseq data of ER-associated mRNAs with/without wtFAM46C
TableS4 from FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy
Authors: Manfrini Nicola , Mancino Marilena , Miluzio Annarita , Oliveto Stefania , Balestra Matteo , Calamita Piera , Alfieri Roberta , Rossi Riccardo L. , Sassoè-Pognetto Marco , Salio Chiara , Cuomo Alessandro , Bonaldi Tiziana , Manfredi Marcello , Marengo Emilio , Ranzato Elia , Martinotti Simona , Cittaro Davide , Tonon Giovanni , Biffo Stefano
Published: April 2023

Secretomics analysis with/without wtFAM46C
Table S2 from A Circle RNA Regulatory Axis Promotes Lung Squamous Metastasis via CDR1-Mediated Regulation of Golgi Trafficking
Authors: Harrison Emily B. , Porrello Alessandro , Bowman Brittany M. , Belanger Adam R. , Yacovone Gabriella , Azam Salma H. , Windham Ian A. , Ghosh Subrata K. , Wang Menglin , Mckenzie Nicholas , Waugh Trent A. , Van Swearingen Amanda E.D. , Cohen Stephanie M. , Allen Devon G. , Goodwin Tyler J. , Mascenik Teresa , Bear James E. , Cohen Sarah , Randell Scott H. , Massion Pierre P. , Major Michael B. , Huang Leaf , Pecot Chad V.
Published: April 2023

miRs individually associated with survival in LUSC TCGA based on median expression of miR genes. FDR values were calculated considering the whole set of genes tested (N=387).
TableS2 from FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy
Authors: Manfrini Nicola , Mancino Marilena , Miluzio Annarita , Oliveto Stefania , Balestra Matteo , Calamita Piera , Alfieri Roberta , Rossi Riccardo L. , Sassoè-Pognetto Marco , Salio Chiara , Cuomo Alessandro , Bonaldi Tiziana , Manfredi Marcello , Marengo Emilio , Ranzato Elia , Martinotti Simona , Cittaro Davide , Tonon Giovanni , Biffo Stefano
Published: April 2023

Expression data Delta47 with/without FNDC3A
Supplementary Figures from Flightless-I Blocks p62-Mediated Recognition of LC3 to Impede Selective Autophagy and Promote Breast Cancer Progression
Authors: He Jian-Ping , Hou Pei-Pei , Chen Qi-Tao , Wang Wei-Jia , Sun Xiao-Yu , Yang Peng-Bo , Li Ying-Ping , Yao Lu-Ming , Li Xiaotong , Jiang Xin-Dong , Chien Kun-Yi , Zhang Zhi-Ming , Wu Qiu-Wan , Cowin Allison J. , Wu Qiao , Chen Hang-Zi
Published: April 2023

This file contains 7 supplementary figures supporting that Flightless-I blocks p62-mediated recognition of LC3 to impede selective autophagy and promote breast cancer progression.
Supplementary Data from Drug Sensitivity Prediction Models Reveal a Link between DNA Repair Defects and Poor Prognosis in HNSCC
Authors: Essers Paul B.M. , van der Heijden Martijn , Verhagen Caroline V.M. , Ploeg Emily M. , de Roest Reinout H. , Leemans C. René , Brakenhoff Ruud H. , van den Brekel Michiel W.M. , Bartelink Harry , Verheij Marcel , Vens Conchita
Published: April 2023

Table S1: List of Enrichr Signatures collections. Table S2: Cross validation performance. Table S3: List of DNA crosslink repair genes. Table S4: Cohort Characteristics and univariate analysis. Table S5: p-values for t-tests of model scores between different clinical variables; companion to Figure S4.
Supplementary Data from Drug Sensitivity Prediction Models Reveal a Link between DNA Repair Defects and Poor Prognosis in HNSCC
Authors: Essers Paul B.M. , van der Heijden Martijn , Verhagen Caroline V.M. , Ploeg Emily M. , de Roest Reinout H. , Leemans C. René , Brakenhoff Ruud H. , van den Brekel Michiel W.M. , Bartelink Harry , Verheij Marcel , Vens Conchita
Published: April 2023

Figure S1: Genetic alterations in the cell line panel. Figure S2: Strategy for internal cross validation of prediction performance. Figure S3: Cross validation at different drug sensitivity cutoffs. Figure S4: Mitomycin C and olaparib sensitivity in the CGP dataset. Figure S5: Relationship between model predictions and clinical parameters. Figure S6: Univariate analysis of variables used in multi-variate analyses. Figure S7: DNA repair defects and hypoxia share downstream effector pathways. Figure S8: Relation of DNA repair defects and cisplatin treatment. Figure S9: Prognostic value of the threeClass model ensemble. Figure S10. Multivariate analysis using disease stage as predictor. Figure S11: Rad51 inhibitor induced growth inhibition in DNA repair defective HNSCC cell lines. Figure S12: Inhibition of migration in scratch assays. Figure S13: Relationship between EMT and DNA repair defects.
Supplementary Information from Integrating Mathematical Modeling with High-Throughput Imaging Explains How Polyploid Populations Behave in Nutrient-Sparse Environments
Authors: Kimmel Gregory J. , Dane Mark , Heiser Laura M. , Altrock Philipp M. , Andor Noemi
Published: April 2023

Supplementary Methods, Figures 1-6 and Tables 1-3.
Figure S4 from Fibroblast-Derived IL33 Facilitates Breast Cancer Metastasis by Modifying the Immune Microenvironment and Driving Type 2 Immunity
Authors: Shani Ophir , Vorobyov Tatiana , Monteran Lea , Lavie Dor , Cohen Noam , Raz Yael , Tsarfaty Galia , Avivi Camila , Barshack Iris , Erez Neta
Published: April 2023

Figure S4 shows that IL-33 is essential for eosinophil recruitment to the metastatic lung.
Figure S3 from Fibroblast-Derived IL33 Facilitates Breast Cancer Metastasis by Modifying the Immune Microenvironment and Driving Type 2 Immunity
Authors: Shani Ophir , Vorobyov Tatiana , Monteran Lea , Lavie Dor , Cohen Noam , Raz Yael , Tsarfaty Galia , Avivi Camila , Barshack Iris , Erez Neta
Published: April 2023

Figure S3 shows bone marrow-derived eosinophil culture and purity.
Figure S1 from Dietary Fructose Promotes Prostate Cancer Growth
Authors: Carreño Daniela V. , Corro Néstor B. , Cerda-Infante Javier F. , Echeverría Carolina E. , Asencio-Barría Catalina A. , Torres-Estay Verónica A. , Mayorga-Weber Gonzalo A. , Rojas Pablo A. , Véliz Loreto P. , Cisternas Pedro A. , Montecinos Viviana P. , San Francisco Ignacio F. , Varas-Godoy Manuel A. , Sotomayor Paula C. , Castro Maite A. , Nualart Francisco J. , Inestrosa Nibaldo C. , Godoy Alejandro S.
Published: April 2023

Downregulation of Glut-5 expression in PC-3 cells using the siRNA methodology.
Figure S4 from YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma
Authors: Shim Jenny , Lee Jasmine Y. , Jonus Hunter C. , Arnold Amanda , Schnepp Robert W. , Janssen Kaitlyn M. , Maximov Victor , Goldsmith Kelly C.
Published: April 2023

Cytotoxic therapy treatment of shYAP and YAP overexpression models
Supplementary Table S5 from Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression
Authors: Barnabas Georgina D. , Lee Joo Sang , Shami Tamar , Harel Michal , Beck Lir , Selitrennik Michael , Jerby-Arnon Livnat , Erez Neta , Ruppin Eytan , Geiger Tamar
Published: April 2023

Supplementary Table S5: Proteomic analysis of the IDH2-perturbed cells
Supplementary Table S2 from Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression
Authors: Barnabas Georgina D. , Lee Joo Sang , Shami Tamar , Harel Michal , Beck Lir , Selitrennik Michael , Jerby-Arnon Livnat , Erez Neta , Ruppin Eytan , Geiger Tamar
Published: April 2023

Supplementary Table S2: List of all identified proteins in the integrated breast proteomic dataset
Supplementary Data from Targeting Obesity-Induced Macrophages during Preneoplastic Growth Promotes Mammary Epithelial Stem/Progenitor Activity, DNA Damage, and Tumor Formation
Authors: Chamberlin Tamara , Clack Megan , Silvers Caylee , Kuziel Genevra , Thompson Victoria , Johnson Haley , Arendt Lisa M.
Published: April 2023

Supplementary data contains Table S1 with detailed list of antibodies, Table S2 with detailed primer list and supplementary materials and methods.
Supplementary Figure and Table legends from Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression
Authors: Barnabas Georgina D. , Lee Joo Sang , Shami Tamar , Harel Michal , Beck Lir , Selitrennik Michael , Jerby-Arnon Livnat , Erez Neta , Ruppin Eytan , Geiger Tamar
Published: April 2023

Supplementary Figure and Table legends
Figure S4 from Targeting Obesity-Induced Macrophages during Preneoplastic Growth Promotes Mammary Epithelial Stem/Progenitor Activity, DNA Damage, and Tumor Formation
Authors: Chamberlin Tamara , Clack Megan , Silvers Caylee , Kuziel Genevra , Thompson Victoria , Johnson Haley , Arendt Lisa M.
Published: April 2023

Figure S4 shows flow cytometry gating strategy and analysis of immune cell populations in mammary glands following depletion of macrophages.
Figure S3 from Targeting Obesity-Induced Macrophages during Preneoplastic Growth Promotes Mammary Epithelial Stem/Progenitor Activity, DNA Damage, and Tumor Formation
Authors: Chamberlin Tamara , Clack Megan , Silvers Caylee , Kuziel Genevra , Thompson Victoria , Johnson Haley , Arendt Lisa M.
Published: April 2023

Figure S3 shows flow cytometery gating strategy and quantification of additional cell types in the mammary gland.
Supplementary Figure S4 from Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression
Authors: Barnabas Georgina D. , Lee Joo Sang , Shami Tamar , Harel Michal , Beck Lir , Selitrennik Michael , Jerby-Arnon Livnat , Erez Neta , Ruppin Eytan , Geiger Tamar
Published: April 2023

Supplementary Figure S4. Metabolic dependencies of transient IDH2 overexpression A-C - Fraction of alpha-ketoglutarate, citrate and aspartate from glutamine in the IDH2-perturbed cells, HCC38 (A), HCC1599 (B) and HCC1143 (C). D-E - Increased ratios of citrate 5/4 and aspartate 3/4 from 13C5-glutamine showed elevated reductive carboxylation in stable and transient IDH2 overexpression. F-H - Transient IDH2 overexpressing cells have increased basal mitochondrial oxygen consumption rate that decreases with oligomycin, reaches maximal respiratory capacity with FCCP and further decreases with ETC complex inhibition with Antimycin A and rotenone. I - Oxidative (citrate m4) and reductive TCA metabolism (citrate m5) correlate with basal IDH2 expression across cell lines. Data are represented as mean {plus minus} SD from three independent experiments (*p-value <0.05; **p-value <0.01).
Figure S1 from Targeting Obesity-Induced Macrophages during Preneoplastic Growth Promotes Mammary Epithelial Stem/Progenitor Activity, DNA Damage, and Tumor Formation
Authors: Chamberlin Tamara , Clack Megan , Silvers Caylee , Kuziel Genevra , Thompson Victoria , Johnson Haley , Arendt Lisa M.
Published: April 2023

Figure S1 outlines the experimental design.
Supplementary Figure S3 from Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression
Authors: Barnabas Georgina D. , Lee Joo Sang , Shami Tamar , Harel Michal , Beck Lir , Selitrennik Michael , Jerby-Arnon Livnat , Erez Neta , Ruppin Eytan , Geiger Tamar
Published: April 2023

Supplementary Figure S3. Mass spectrometry based proteomic analysis of IDH2 perturbed cells A - Volcano plot shows the differentially expressed proteins in the three cell lines (HCC38, HCC1599 and HCC1143) upon IDH2 perturbations. The proteins above the black line are t-test significant with permutation-based FDR 0.1. Proteins involved in the indicated functional processes and pathways are highlighted. B - The significant enrichments of KEGG and GOBP categories of cellular processes in the cells with high and low IDH2 expression. The listed enriched processes are significant by Fisher exact test with FDR 0.02.
Supplementary Figure S2 from Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression
Authors: Barnabas Georgina D. , Lee Joo Sang , Shami Tamar , Harel Michal , Beck Lir , Selitrennik Michael , Jerby-Arnon Livnat , Erez Neta , Ruppin Eytan , Geiger Tamar
Published: April 2023

Supplementary Figure S2. Cell proliferation and glycolytic activity upon transient IDH2 overexpression A-B - Quantification of the integrated density of cellROX staining in control and IDH2-overexpressing cells (A) and in the control and IDH2 knockout cells (B) using ImageJ. C -Western blot analysis shows transient overexpression of IDH2 in HCC1500, HCC1954 and in HCC1937 breast cancer cell lines, with GFP overexpression as control. Vinculin serves as loading control. D-F - Transient overexpression of IDH2 does not affect the proliferation rate of the cell lines HCC1954 (D), HCC1500 (E) and HCC1937 (F). G - Re-expression of IDH2 in knockout HCC1143 cells with mCherry (mCh) as control. H - Rescue of sensitivity to oxidative damage in IDH2 knockout cells with re-expression of IDH2. I-K - Increased glucose uptake and lactate secretion, accompanied with elevated extracellular acidification rates measured by Seahorse flux analyzer showed higher glycolytic activity upon transient IDH2 overexpression. (*p-value <0.05; **p-value <0.01).
Supplemental Figures from A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors
Authors: Barnoud Thibaut , Leung Jessica C. , Leu Julia I-Ju , Basu Subhasree , Poli Adi Narayana Reddy , Parris Joshua L.D. , Indeglia Alexandra , Martynyuk Tetyana , Good Madeline , Gnanapradeepan Keerthana , Sanseviero Emilio , Moeller Rebecca , Tang Hsin-Yao , Cassel Joel , Kossenkov Andrew V. , Liu Qin , Speicher David W. , Gabrilovich Dmitry I. , Salvino Joseph M. , George Donna L. , Murphy Maureen E.
Published: April 2023

Supplemental figures file
Supplementary Text from Intake of Dietary Fruit, Vegetables, and Fiber and Risk of Colorectal Cancer According to Molecular Subtypes: A Pooled Analysis of 9 Studies
Authors: Hidaka Akihisa , Harrison Tabitha A. , Cao Yin , Sakoda Lori C. , Barfield Richard , Giannakis Marios , Song Mingyang , Phipps Amanda I. , Figueiredo Jane C. , Zaidi Syed H. , Toland Amanda E. , Amitay Efrat L. , Berndt Sonja I. , Borozan Ivan , Chan Andrew T. , Gallinger Steven , Gunter Marc J. , Guinter Mark A. , Harlid Sophia , Hampel Heather , Jenkins Mark A. , Lin Yi , Moreno Victor , Newcomb Polly A. , Nishihara Reiko , Ogino Shuji , Obón-Santacana Mireia , Parfrey Patrick S. , Potter John D. , Slattery Martha L. , Steinfelder Robert S. , Um Caroline Y. , Wang Xiaoliang , Woods Michael O. , Van Guelpen Bethany , Thibodeau Stephen N. , Hoffmeister Michael , Sun Wei , Hsu Li , Buchanan Daniel D. , Campbell Peter T. , Peters Ulrike
Published: April 2023

Supplementary Text
Table S1 from Remission of Spontaneous Canine Tumors after Systemic Cellular Viroimmunotherapy
Authors: Cejalvo Teresa , Perisé-Barrios Ana Judith , del Portillo Isabel , Laborda Eduardo , Rodriguez-Milla Miguel A. , Cubillo Isabel , Vázquez Fernando , Sardón David , Ramirez Manuel , Alemany Ramon , del Castillo Noemí , García-Castro Javier
Published: April 2023

List of used antibodies
Legends from Remission of Spontaneous Canine Tumors after Systemic Cellular Viroimmunotherapy
Authors: Cejalvo Teresa , Perisé-Barrios Ana Judith , del Portillo Isabel , Laborda Eduardo , Rodriguez-Milla Miguel A. , Cubillo Isabel , Vázquez Fernando , Sardón David , Ramirez Manuel , Alemany Ramon , del Castillo Noemí , García-Castro Javier
Published: April 2023

Supplementary Figure Legends
Supplementary Table S6 from Intake of Dietary Fruit, Vegetables, and Fiber and Risk of Colorectal Cancer According to Molecular Subtypes: A Pooled Analysis of 9 Studies
Authors: Hidaka Akihisa , Harrison Tabitha A. , Cao Yin , Sakoda Lori C. , Barfield Richard , Giannakis Marios , Song Mingyang , Phipps Amanda I. , Figueiredo Jane C. , Zaidi Syed H. , Toland Amanda E. , Amitay Efrat L. , Berndt Sonja I. , Borozan Ivan , Chan Andrew T. , Gallinger Steven , Gunter Marc J. , Guinter Mark A. , Harlid Sophia , Hampel Heather , Jenkins Mark A. , Lin Yi , Moreno Victor , Newcomb Polly A. , Nishihara Reiko , Ogino Shuji , Obón-Santacana Mireia , Parfrey Patrick S. , Potter John D. , Slattery Martha L. , Steinfelder Robert S. , Um Caroline Y. , Wang Xiaoliang , Woods Michael O. , Van Guelpen Bethany , Thibodeau Stephen N. , Hoffmeister Michael , Sun Wei , Hsu Li , Buchanan Daniel D. , Campbell Peter T. , Peters Ulrike
Published: April 2023

Supplementary Table S6
Figure S4 from Remission of Spontaneous Canine Tumors after Systemic Cellular Viroimmunotherapy
Authors: Cejalvo Teresa , Perisé-Barrios Ana Judith , del Portillo Isabel , Laborda Eduardo , Rodriguez-Milla Miguel A. , Cubillo Isabel , Vázquez Fernando , Sardón David , Ramirez Manuel , Alemany Ramon , del Castillo Noemí , García-Castro Javier
Published: April 2023

Flow cytometry gating strategy of immune subpopulation analysis in dog-derived peripheral blood
Supplemental Figure Legends from Linking Transcriptomic and Imaging Data Defines Features of a Favorable Tumor Immune Microenvironment and Identifies a Combination Biomarker for Primary Melanoma
Authors: Gartrell-Corrado Robyn D. , Chen Andrew X. , Rizk Emanuelle M. , Marks Douglas K. , Bogardus Margaret H. , Hart Thomas D. , Silverman Andrew M. , Bayan Claire-Audrey Y. , Finkel Grace G. , Barker Luke W. , Komatsubara Kimberly M. , Carvajal Richard D. , Horst Basil A. , Chang Rui , Monod Anthea , Rabadan Raul , Saenger Yvonne M.
Published: April 2023

Supplemental Figure Legends
Table. S4 from Hes1 Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma
Authors: Matsumori Tomoaki , Kodama Yuzo , Takai Atsushi , Shiokawa Masahiro , Nishikawa Yoshihiro , Matsumoto Tomonori , Takeda Haruhiko , Marui Saiko , Okada Hirokazu , Hirano Tomonori , Kuwada Takeshi , Sogabe Yuko , Kakiuchi Nobuyuki , Tomono Teruko , Mima Atsushi , Morita Toshihiro , Ueda Tatsuki , Tsuda Motoyuki , Yamauchi Yuki , Kuriyama Katsutoshi , Sakuma Yojiro , Ota Yuji , Maruno Takahisa , Uza Norimitsu , Marusawa Hiroyuki , Kageyama Ryoichiro , Chiba Tsutomu , Seno Hiroshi
Published: April 2023

The characteristics of analyzed ICC patients.
Supplementary Figure 4 from Cellular and Genetic Determinants of the Sensitivity of Cancer to α-Particle Irradiation
Authors: Yard Brian D. , Gopal Priyanka , Bannik Kristina , Siemeister Gerhard , Hagemann Urs B. , Abazeed Mohamed E.
Published: April 2023

Cellular morphometry affects survival after alpha-particle irradiation.
Supplementary Table 1 from Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer
Authors: Li Yingjie , Bai Liangliang , Yu Huichuan , Cai Du , Wang Xiaolin , Huang Baoyuan , Peng Shaoyong , Huang Meijin , Cao Guangwen , Kaz Andrew M. , Grady William M. , Wang Jianping , Luo Yanxin
Published: April 2023

Table S1. The distribution and calculated pI of peptides in the peptide arrays
Fig. S4 from Hes1 Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma
Authors: Matsumori Tomoaki , Kodama Yuzo , Takai Atsushi , Shiokawa Masahiro , Nishikawa Yoshihiro , Matsumoto Tomonori , Takeda Haruhiko , Marui Saiko , Okada Hirokazu , Hirano Tomonori , Kuwada Takeshi , Sogabe Yuko , Kakiuchi Nobuyuki , Tomono Teruko , Mima Atsushi , Morita Toshihiro , Ueda Tatsuki , Tsuda Motoyuki , Yamauchi Yuki , Kuriyama Katsutoshi , Sakuma Yojiro , Ota Yuji , Maruno Takahisa , Uza Norimitsu , Marusawa Hiroyuki , Kageyama Ryoichiro , Chiba Tsutomu , Seno Hiroshi
Published: April 2023

Analyzes of immunohistochemistry and relative mRNA expression levels in liver sections of AlbcreKP (WT), AlbcreKP; RosaNotchOE/+, and AlbcreKP; RosaNotchOE/+; Hes1flox/flox mice at 8 weeks of age.
SupplementaryMovieLegends.pdf from The Amino-Terminal Oligomerization Domain of Angiopoietin-2 Affects Vascular Remodeling, Mammary Gland Tumor Growth, and Lung Metastasis in Mice
Authors: Kapiainen Emmi , Kihlström Minna K. , Pietilä Riikka , Kaakinen Mika , Ronkainen Veli-Pekka , Tu Hongmin , Heikkinen Anne , Devarajan Raman , Miinalainen Ilkka , Laitakari Anna , Ansarizadeh Mohammadhassan , Zhang Qin , Wei Gong-Hong , Ruddock Lloyd , Pihlajaniemi Taina , Elamaa Harri , Eklund Lauri
Published: April 2023

Legends for Sup movies 1 and 2
Supplementary Data from E2A Modulates Stemness, Metastasis, and Therapeutic Resistance of Breast Cancer
Authors: López-Menéndez Celia , Vázquez-Naharro Alberto , Santos Vanesa , Dubus Pierre , Santamaría Patricia G. , Martínez-Ramírez Ángel , Portillo Francisco , Moreno-Bueno Gema , Faraldo Marisa M. , Cano Amparo
Published: April 2023

Supplementary Methods and Supplementary Tables S1-S4
Supplemental Figures S1-S6 from 14-3-3σ Functions as an Intestinal Tumor Suppressor
Authors: Winter Markus , Rokavec Matjaž , Hermeking Heiko
Published: April 2023

Supplemental Figures S1-S6 including legends
Figure S3 from Insights into the Links between MYC and 3D Chromatin Structure and Epigenetics Regulation: Implications for Cancer Therapy
Authors: Amjadi-Moheb Fatemeh , Paniri Alireza , Akhavan-Niaki Haleh
Published: April 2023

Triplex-forming sites of TERC and MEG3 at the MYC locus and its 2000 bp upstream sequence. The figure represents potential binding sites of each lncRNA and selected triplex motifs between them and the corresponding regulatory sites of the MYC.
Supplementary Data 6 from SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer
Authors: Martinez Rafael S. , Salji Mark J. , Rushworth Linda , Ntala Chara , Rodriguez Blanco Giovanny , Hedley Ann , Clark William , Peixoto Paul , Hervouet Eric , Renaude Elodie , Kung Sonia H.Y. , Galbraith Laura C.A. , Nixon Colin , Lilla Sergio , MacKay Gillian M. , Fazli Ladan , Gaughan Luke , Sumpton David , Gleave Martin E. , Zanivan Sara , Blomme Arnaud , Leung Hing Y.
Published: April 2023

List of antibodies
Supplementary Data 4 from SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer
Authors: Martinez Rafael S. , Salji Mark J. , Rushworth Linda , Ntala Chara , Rodriguez Blanco Giovanny , Hedley Ann , Clark William , Peixoto Paul , Hervouet Eric , Renaude Elodie , Kung Sonia H.Y. , Galbraith Laura C.A. , Nixon Colin , Lilla Sergio , MacKay Gillian M. , Fazli Ladan , Gaughan Luke , Sumpton David , Gleave Martin E. , Zanivan Sara , Blomme Arnaud , Leung Hing Y.
Published: April 2023

SLFN5_binding sites
Figure S8 from Pharmacological Disruption of the Notch1 Transcriptional Complex Inhibits Tumor Growth by Selectively Targeting Cancer Stem Cells
Authors: Alvarez-Trotta Annamil , Guerrant William , Astudillo Luisana , Lahiry Mohini , Diluvio Giulia , Shersher Elena , Kaneku Hugo , Robbins David J. , Orton Darren , Capobianco Anthony J.
Published: April 2023

Models of stem-like MDA-MB-231 and OE33 populations are sensitive to NADI-351