bluuebunny/crossref_metadata_2025 huggingface dataset:
Pripremljenost za krizno komuniciranje velikih poduzeća u Hrvatskoj
Authors: Trbušić Davor , Jakopović Hrvoje
Published: July 2023

Rad proučava važnost i mogućnosti pripreme za krizno komuniciranje u kontekstu hrvatskih ‎velikih poduzeća kao najkompleksnijih organizacijskih sustava. Autori su uz pomoć polustrukturiranih ‎intervjua ispitali kakva je njihova razina pripremljenosti za krizno komuniciranje i kojim se metodama, ‎tehnikama i alatima služe komunikacijski stručnjaci na upravljačkim pozicijama i njihovi timovi kako bi‎ umanjili negativne posljedice kriznih situacija. Rezultati istraživanja provedenog na uzorku od deset ispitanika,‎ koji predstavljaju organizacije iz različitih područja (turizam, prijevoz, telekomunikacije, proizvodnja‎ hrane i pića, poštanski sektor), pokazuju kako su velika poduzeća u Hrvatskoj dobro pripremljena za‎ krizno komuniciranje. To je potvrđeno kroz postojanje kriznih komunikacijskih planova, standardiziranih‎ protokola za krizne situacije, priručnika, formiranih kriznih timova te redovitih simuliranja kriznih situacija‎ u velikim poduzećima koja su zastupljena u istraživanju. Rezultati pokazuju kako samo jedno poduzeće‎ primjenjuje model integriranog upravljanja rizicima (Enterprise Risk Management, ERM). Kada je u pitanju ‎krizno komuniciranje i odnosi s medijima, ispitanici navode standardne tehnike odnosa s javnošću,‎ poput priopćenja za medije, izjava za medije, konferencija za novinare, brifinga za novinare, intervjua i‎ gostovanja u medijima. Rezultati istraživanja također upućuju na posebnu važnost glasnogovornika u ‎krizi, što pokazuje koliko je bitan odabir prave osobe za tu istaknutu poziciju u kriznom komuniciranju.‎
Frozen Food Quality Control Using Statistical Process Control Methods and Failure Mode and Effect Analysis
Authors: Putra Mochammad Nabil Ferdianto Pratama , Cahyana Atika Sidhi
Published: July 2023

The research was conducted in UD Mulia Jaya to look out the main causes of defects in frozen food products and to reduce defects in the product of making klasu bread. It is known that the production of klasu bread is 333,490 pcs, product defects are 18,716 pcs, and the average production per day is 6,669 pcs with an average daily product defect of 374 pcs. The defect has exceeded the product defect tolerance limit set by the business owner. The method used Statistical Process Control (SPC) and Failure Mode and Effect Analysis (FMEA). The results showed that the biggest cause of defects was filling out the surface (leaky) with a total of 7,695. Calculation of the Risk Priority Number (RPN) obtained a value of 168. The most dominant factor the environmental factor with recommendations for repairing insulation on each production line to maximize employee performance in reducing product defects.
The largest Chinese cohort study indicates homologous recombination pathway gene mutations as another major genetic risk factor for colorectal cancer with heterogeneous clinical phenotypes
Authors: Xu Yun , Liu Kai , Li Cong , Li Minghan , Liu Fangqi , Zhou Xiaoyan , Sun Menghong , Ranganathan Megha , Zhang Liying , Wang Sheng , Hu Xin , Xu Ye
Published: July 2023

Background: Colorectal cancer (CRC) is one of the most common malignancies globally with estimated 1.87 million new cases annually. Genetic factors were associated with over 30% of CRC incidence. However, the mutations in CRC-susceptibility genes recommended by the National Comprehensive Cancer Network (NCCN) guidelines accounted for only 5-10% of CRC cases, suggesting a large proportion of CRC-susceptibility genes remain unknown. As previous works on hereditary CRC were largely designed to analyze germline mutations in patients with a single category of genetic high-risk factor, this study aims to explore the genetic mutations underlying five categories of genetic high-risk factors in clinic.
Methods: From January 2015 to December 2018, 2181 patients from a cohort of 8270 consecutive CRC cases were retrospectively enrolled, covering five categories of genetic high-risk factors. Their germline mutations under each category were detected and analyzed in association with CRC susceptibility, clinical phenotypes, and prognoses.
Results:In total 462 pathogenic/likely pathogenic genetic variants were detected in 19.3% CRC patients enrolled. Mutations in the mismatch repair (MMR) genes were identified in 9.1% patients, most prevalent across all high-risk groups. Mutations in homologous recombination (HR) pathway genes were detected in 6.5% patients, which were mostly penetrated in early onset, family cancer history and extra-colonic cancer risk groups. HR pathway gene mutations, including BARD1, RAD50 and ATM, were associated with an increased risk of CRC in the cohort with an odds ratio of 2.8, 3.1 and 3.1-fold, respectively. CRC patients carrying different genetic mutations manifested heterogeneous phenotypes in clinicopathology and long-term prognoses, for which Lynch Syndrome demonstrated better prognoses than other groups, including those with HR pathway mutations.
Conclusions: This largest Chinese cohort study of high-risk hereditary CRC is the first to cover five categories of genetic high-risk factors, which greatly expanded the list of CRC-susceptibility mutations. In contrast to the MMR mutations of Lynch syndrome, the study reveals for the first time at population level that carriers of mutations in the HR pathway genes are significantly susceptible to CRC, implicating HR pathway gene mutations as another major contributor for increased risk of developing CRC.
Trial registration: Retrospectively registered.
MODERNISASI DAN DEMOKRATISASI PENDIDIKAN ISLAM MENURUT FAZLUR RAHMAN
Authors: Suryadi Ahmad , Damopolii Muljono , . Salahuddin
Published: July 2023

This study discusses the modernization and democratization of Islamic education according to Fazlur Rahman. This research was conducted with the aim of: 1) knowing the nature of the concept of modernization of Islamic education according to Fazlur Rahman. 2) knowing the nature of the concept of democratization of Islamic education according to Fazlur Rahman. 3) knowing the variety of modernization of Islamic education according to Fazlur Rahman and 4) knowing the variety of democratization of Islamic education according to Fazlur Rahman. Basically this research is a literature research or library research using a philosophical analysis approach and a historical approach. Data sources used are primary and secondary data sources. The results of this study indicate that the concept of modernization of Islamic education according to Fazlur Rahman, namely: education is the starting point for reform. Any renewal model in Islam would never have happened without the involvement of education in it. Fazlur Rahman emphasized the concept of democratization in freedom for humans to develop creative attitudes and knowledge that exist in humans in order to improve their lives. Furthermore according to Fazlur Rahman that education should be held by promoting the freedom of students, because without the existence of a creative attitude students are difficult to develop. The variety of modernization of Islamic education that was initiated by Fazlur Rahman includes five aspects, namely: The Purpose of Islamic Education, the Education System, Educators, Students, and Educational Facilities. The various types of democratization of Islamic education according to Fazlur Rahman are: respecting human potential and the development and implications of humans on Islamic education.
Hiperplasia papilar endotelial intravascular en un dedo de la mano
Authors: García-Jiménez Antonio
Published: July 2023

Se presenta un caso de hiperplasia papilar endotelial intravascular, una lesión vascular benigna no neoplásica poco frecuente, también conocida como tumor de Masson, que se localizaba en la cara palmar de la falange distal del dedo pulgar de la mano izquierda de un hombre de 60 años. El diagnóstico solo pudo establecerse tras su exéresis mediante el estudio histológico de la lesión, pues los estudios de imagen previos mediante resonancia magnética no fueron concluyentes.
A pesar de que el pronóstico de la hiperplasia papilar endotelial intravascular es excelente, es importante establecer un diagnóstico diferencial de otras patologías que requieren intervenciones terapéuticas más extensivas.
PEDAGOGICAL CONCEPT OF AN ELEMENTARY SCHOOL TEACHER IN THE TVER TEACHER'S SCHOOL OF P.P. MAKSIMOVICH
Authors: Ильина Т.А.
Published: July 2023

Анализируется педагогическая концепция учителя начальной школы, теоретически сформированная в трудах первых педагогов Тверской женской учительской школы им. П.П. Максимовича и практически воплощаемая в жизнь на протяжении всех лет работы этой школы (1870- 1919). Подробно рассматриваются личностные качества будущих учителей, которые должны были быть сформированы в процессе обучения.

The pedagogical concept of an elementary school teacher is analyzed, theoretically formed in the works of the first teachers of the P.P. Maksimovich Tver Women's Teacher's School and practically implemented throughout all the years of work of this school (1870-1919). The personal qualities of future teachers, which should have been formed in the learning process, are considered in detail.
СРАВНИТЕЛЬНЫЙ АНАЛИЗ МЕТОДОВ ДЕРЕВЬЕВ РЕШЕНИЙ И НЕЙРОННЫХ СЕТЕЙ В ЗАДАЧЕ КЛАССИФИКАЦИИ КРЕДИТНЫХ ОРГАНИЗАЦИЙ
Authors: Акишина Е. П. , Иванов В. В. , Крянев А. В. , Приказчикова А. С.
Published: July 2023

В последние годы деревья решений и нейронные сети широко применяются в задачах компьютерного зрения, таких как распознавание объектов, классификация текстов, распознавание жестов, обнаружение спама, семантическая сегментация и кластеризация данных. В статье рассматривается применение методов деревьев решений и искусственных нейронных сетей в задаче классификации кредитных организаций как объектов экономической безопасности. Представлены результаты анализа данных о деятельности кредитных организаций с использованием разных методов деревьев решений: C5, CHAID, C&R и QUEST, а также нейронных сетей. Наивысшая общая точность классификации анализируемых объектов была достигнута с помощью алгоритма деревьев решений С5 и составила 81 %. Общая точность классификации при применении алгоритма CHAID составила 68 %, алгоритма C&R – 71 %, алгоритма QUEST – 66 %. На основании результатов алгоритма C5 сгенерирован набор правил для определения принадлежности банка к определенному классу. Согласно методам деревьев решений и нейронным сетям были отобраны наиболее информативные показатели деятельности кредитных организаций с точки зрения их разбиения на два класса: благонадежные и высоко-рисковые.
Mediating Role of Employee Engagement on Person-Organization Fit and Turnover Intention in Indonesia
Authors: Margaretha Meily , Zaniarti Sri , Indrawan Dava
Published: July 2023

Purpose: The aim of this study is to examine the effect of person-organizational fit (PO-fit) on turnover intention. It also analyzes employees' engagement (EE) as a variable that mediates the relationship between the two variables.
 
Theoretical framework:  An organization tends not to avoid the problem of turnover intention when employees voluntarily submit resignations letter. Therefore, all companies need to understand the factors such as person-organization fit (PO-fit) that can affect this turnover. Previous studies failed to fully show a negative relationship between PO-fit and turnover intention. Theoretically, there is an increased engagement when employees have values that suit the organization's own. It ultimately increases individuals' intention to remain in the company where they work.
 
Design/Methodology/Approach:  The respondents of this study were 366 employees from several big cities on Java island in Indonesia. The sampling criteria were those that had worked for at least 1 year. This survey was conducted using internet-based questionnaires and data were analyzed by testing the validity and reliability, as well as the hypotheses.
 
Findings: The results showed a significant relationship between PO-fit and turnover intention while examining the total 366 employees in Indonesia. Furthermore, all hypotheses are supported because there was an indirect effect of EE on turnover intention.
 
Research, practical & social implications: This study has several implications including managers being required to ensure that organizational culture is conveyed to increase the PO-fit value between employees and their organization.
 
Originality/Value: The research focuses on studying examine the effect of person-organizational fit (PO-fit) on turnover intention. Moreover, only a few studies that discuss employee engagement to be a mediator of PO-fit and turnover intention. Therefore, this study examines the EE role as a mediating variable in explaining the relationship between PO-fit and employee turnover in Indonesia.
The Analysis of Locutionary Speech Acts on YouTube Channel Arisa Nur Aini
Authors: Sari Ismi Aulia , Setyowati Shinta Anggraeni , Kusuma Marchell Teja , Buono Setiya Adi , Utomo Asep Purwo Yudi
Published: July 2023

Locution is a speech act that exists in pragmatic studies, locution itself can be interpreted as a speech act that states something where the action produces a meaningful expression. The other name of this speech act is the act of saying something. In everyday life, we definitely find locutionary speech acts, one of which is in the form of Indonesian language learning videos on YouTube. Therefore, researchers want to examine more deeply about the locutionary speech act. This research is focused on one of the fields of pragmatics, namely speech acts. The analysis was conducted on learning videos on Arisa Nur Aini's YouTube channel, namely on the playlist of Indonesian Language Materials for Grade 11 SMA semester 1 which was motivated by the discovery of the use of various types of locutionary speech acts in the sentence. The data source used is the Indonesian learning video of Grade 11 Material. The data used is in the form of utterances in the learning video which are included in the type of locutionary speech acts. The research method used in this research is a qualitative descriptive method which uses data collection techniques in the form of listening and recording techniques. The purpose of this study is to determine the types of locutionary speech acts in playlists of Indonesian Language Materials for Grade 11 SMA semester 1 on Arisa Nur Aini's youtube channel. From the analysis, it is found that the types of locutionary speech acts in the form of interrogative sentences consisting of 7 utterances, declarative sentences consisting of 20 utterances, and imperative locutionary speech acts consisting of 7 utterances. With this analysis, the readers are expected to be able to interpret and classify the types of locutionary speech acts. Keywords: lokusi, pragmatic, arisa, youtube, sma
Relationship of Scores of Empathy with Human Body Dissection and Gender among Undergraduate Medical Students of BPKIHS
Authors: Shah Sandip , Koirala Sarun , Khanal Laxman , Baral Presha
Published: July 2023

Introduction: Medical empathy is defined as the predominantly cognitive attribute that involves the ability to understand patients’ experiences, concerns, and perspectives, and communicate this understanding with the intention of helping.
Objectives: The main aim of present study was to determine the relationship of human body dissection and gender with level of empathy among the first and third year undergraduate medical students of B.P. Koirala Institute of Health Sciences.
Methods: A cross-sectional study conducted on first and third years medical students between the periods of August 2020 to March 2021. “The Jefferson Scale of Physician Empathy-Student version” was used for assessment of empathy. Sample size of the study was 176 and the results were analyzed in Statistical Package for the Social Sciences, version 11.5. Student’s t-test, ANOVA and bivariate correlation models were employed for statistical analysis. The p <0.05 was considered as the significant level.The respondent rate of questionnaire was 88%.
Results: The mean empathy score was found to be 88.13.The empathy score increased with increase of age (p<0.001) and year of course (p=0.066).The empathy score of Nepalese student was found to be lower as compare to Non–Nepalese student (p=0.016). The bivariate correlation analysis between empathy score and age was found to have positive correlation with statistical significant level (rs=0.270; p<0.001).
Conclusions: These results suggest that the empathy score of Nepalese students’ increases with age and year of medical education.
Challenges and scope of movement disorder surgery in Nepal
Authors: Shrestha Resha , Gurung Pritam , Pant Basant
Published: July 2023

Movement disorders (MD) are  clinical syndromes with either excess or paucity of voluntary or involuntary movements without weakness or spasticity. Hypokinetic MD  includes primary and secondary Parkinsons disease and Parkinsons syndrome and hyperkinetc MD includes dystonia, tremors, choreas and dyskinesias. Although medical treatment is the mainstay of treatment modality, in selected cases surgical treatment is a safe option
SRI LANKAN STOCK MARKET VOLATILITY ANALYSIS: AN ARMA- GARCH APPROACH
Authors: Samarawickrama I.D.W.  , Pallegedara A.
Published: July 2023

Beyond its role in capital generation, a stock market is emulated as a facet in economic development indication. Sri Lankan stock market, the Colombo Stock Exchange (CSE) is a languidly developing market known for instability and periodical fluctuations increasing the volatility risk for the investors. Toward market development, it is imperative in attracting and retaining long term investors. Thus, the study aimed to identify the dynamics of the CSE through volatility estimation of the Sri Lankan stock market during a high volatile period. Further, the use of ARMA-GARCH models aims to contribute to the local empirical studies on the applicability of ARMA-GARCH models in the Sri Lankan context.

The study used the daily closing prices of the All-Share-Price Index (ASPI) from January 2018 to December 2022 in log return volatility. Owing to the non-normality and serial dependence conditions inherent in the data, the study developed an ARMA (2,2) mean equation and separate volatility equation applying symmetric models of GARCH, and TGARCH and asymmetric GARCH models of EGARCH, and GJR-GARCH.

The study findings identified that asymmetric GARCH models are more reliable in volatility estimation and forecasting. Further, ASPI indicated a leverage effect where negative information caused idiosyncratic volatility.

Keywords: ARMA-GARCH, GARCH, Leverage Effect, Stock Markets, Volatility
Single Well Coning Problem and Applicable Solutions
Authors: Alkhalissi Raad Mohammed Jawad
Published: July 2023

One of the most important and common problems in petroleum engineering; reservoir, and production engineering is coning; either water or gas coning. Almost 75% of the drilled wells worldwide contains this problem, and in Iraq water coning problem is much wider than the gas coning problem thus in this paper we try to clarify most of the reasons causing water coning and some of applicable solutions to avoid it using the simulation program (CMG Builder) to build a single well model considering an Iraqi well in north of Iraq black oil field with a bottom water drive, Coning was decreased by 57% by dividing into sub-layers (8) layers rather than (4) layers, also it was decreased (Coning) by 45% when perforation numbers and positions was changed.
Proposal for the implementation of humanoid robots in teaching English as a foreign
language in Croatia
Authors: Karabin Petra
Published: July 2023

The particularity of foreign language teaching is that it includes a variety of teaching topics, and in addition to that, language skills are being acquired with the use of various teaching tools. The latest teaching tool, which is being gradually introduced in foreign language teaching, is an educational robot (Nikolić, 2016). According to Randall (2019), the most widely used robots in the teaching process are those with an anthropomorphic appearance, the so-called humanoid robots.As the development and implementation of robots as teaching tools in the teaching process is still in its early stages in the Republic of Croatia, this review paper aims to offer the participants of the educational process a description of three humanoid robots (Meccano Meccanoid 2.0 G16, Leju Aelos 1S, UBTECH Alpha 1 Pro) that can be used in teaching English as a foreign language in primary education. Along with the robots’ description, this paper offers the examples of teaching activities that correlate two different subjects (English as a foreign language and ICT) and achieve interdisciplinary educational and learning outcomes. Proposed teaching activities, which will be only one of the activities of the lesson, will include various types of class organization and usage of different educational materials. Alongside, they will be complemented by actual textbook examples and a proposal regarding the grade in which they can be used.
Caracterização do perfil epidemiológico e clínico dos casos de arboviroses urbanas transmitidas pelo Aedes no Brasil, nos anos de 2017 a 2021
Authors: Rios Matheus Marinho , Ferreira Milene Silveira , Azevedo Raimunda do Socorro da Silva , Silva Maria Inês Caricchio da , Moraes Junior Rudival Faial de , Silva Mikelly Santos Coutinho da , Vasconcelos Pedro Fernando da Costa , Martins Lívia Caricio
Published: July 2023

As infecções por arbovírus aumentaram dramaticamente durante os últimos anos. A sintomatologia semelhante na fase inicial da doença dificulta o diagnóstico diferencial e o manejo clínico. Esse estudo descreve o perfil epidemiológico e clínico dos casos de arboviroses urbanas transmitidas por Aedes aegypti no Brasil no período de 2017 a 2021. Foram analisados 1.145 casos humanos disponíveis no Sistema de Gerenciador de Ambiente Laboratorial (GAL) positivos para os vírus Chikungunya (CHIKV) (741/64,71%), vírus Dengue (DENV) (381/33,27%) e vírus Zika (ZIKV) (23/2%). As informações clínicas e epidemiológicas foram obtidas a partir das fichas de investigação epidemiológicas do Sistema de Informação de Agravos de Notificação (SINAN).  A maioria dos infectados eram do sexo feminino (63%), pardos (31%) e faixa etária de 31 a 40 anos de idade. Os sintomas mais relatados foram febre (90%), artralgia intensa (67,3%), cefaleia (53,2%), mialgia (52,8%) e exantema (50%). Durante a fase aguda (D0 a D6) foi observado que os indivíduos infectados com DENV apresentavam sinais/sintomas mais elevados dos que os infectados com o ZIKV e CHIKV. Na fase de convalescência (D7 a >D15), os sinais/sintomas dos infectados com CHIKV elevaram-se e os com DENV e ZIKV declinaram. Quando se considerou a avaliação dos sinais/sintomas em uma proporção aumentada (≥10%) foram observados entre os infectados com o CHIKV os sinais/sintomas apresentaram-se em uma proporção aumentada mais tardiamente (D6 a >D15). A caracterização do perfil clínico das arboviroses pode direcionar o diagnóstico clínico diferencial, bem como, correlacionar os aspectos epidemiológicos com a evolução da doença.
Clinical and genetic characteristics in lymphoma patients with a second solid malignancy
Authors: Zhou Di , Han Leng , Jin Chanjuan , Bi Lintao
Published: July 2023

Diagnosis and treatment of multiple primary malignancies are becoming a new challenge in clinical practice worldwide. The present study aimed to characterize the clinical and genetic features of multiple primary malignancies in patients with synchronous or metachronous lymphoma and another solid tumor. We retrospectively analyzed 11 cases with lymphoma and another solid tumor. The germline mutations in plasma cell-free DNA samples and somatic mutations in lymphoma and solid tumor tissue samples were identified using targeted next-generation sequencing. In the 11 lymphoma patients, the most common type of concurrent solid tumor was colon adenocarcinoma (case 3, 5, 9 11) followed by papillary thyroid carcinoma (case 1, 7, 10). Metachronous lymphoma and solid tumor in 6 patients were treated with corresponding standard therapy asynchronously. Chemotherapy for colon adenocarcinoma during the interval of lymphoma chemotherapy led to excellent outcome in two patients. Immediate chemotherapy for lymphoma plus elective surgery for synchronous papillary thyroid carcinoma also yielded good prognosis in two patients with synchronous double primaries. Interestingly, we found that 10 of 11 patients with lymphoma and another solid tumor harbored germline mutations in Fanconi anemia complementation group (FANC) genes, including FANCI, FANCA, FANCG, FANCL, FANCD1, FANCF, FANCJ, and FANCS. In summary, comprehensive study of the clinical and genetic features of patients with multiple primary malignancies may improve diagnosis and treatment in the future. Mutations in FANC genes might be a predisposition to tumorigenesis of lymphoma patients with a second solid malignancy.
Postoperative dysesthesia after PVCR without anterior support applied in Yang's type A severe spinal kyphoscoliosis
Authors: Wu Hangqin , Ding Jie , Yang Junlin , Sui Wenyuan
Published: July 2023

Backgrounds

The incidence and characteristics of postoperative dysesthesia (POD) have not been reported for posterior vertebral column resection (PVCR) in the treatment of severe spinal kyphoscoliosis.

Objective

The objective of the study is to investigate the incidence and characteristics of POD in PVCR without anterior support applied in Yang's type A severe spinal kyphoscoliosis.

Material and methods

From August 2010 to December 2019, 167 patients diagnosed with Yang's type A severe spinal kyphoscoliosis who underwent PVCR without anterior support applied were retrospectively reviewed. All the patients were monitored using five modes of intraoperative multimodal neurophysiological monitoring. Neuromonitoring data, radiographic parameters, and neurological complications were reviewed and analyzed. The incidence and characteristics of POD were further summarized. POD was defined as dysesthetic pain or burning dysesthesia which could be caused by spinal cord kinking or dorsal root ganglion (DRG) injury but with no motor deficits.

Results

PVCR without anterior support was successfully conducted in all 167 patients. Intraoperative monitoring events occurred in five patients. One out of these five patients showed postoperative spinal cord injury (Frankel level C) but completely recovered within 9 months postoperation (Frankel level E). The number of levels and osteotomy space for vertebra resection were 1.28 and 3.6 cm, respectively. POD was confirmed in three patients (3/167, 1.8%), characterized as kyphosis with the apex vertebrae in T12 with the kyphotic Cobb angles of 100°, 115°, and 122°, respectively. The osteotomy space of vertebra resection in these three patients were 3.9, 3.8, and 4.2 cm, respectively. After the treatment by drug administration, they reported pain relief for 12–36 days. The pain gradually moved to the distal end of a proper DRG innervated region near the end.

Conclusions

In this study, the incidence rate of POD in Yang's type A severe spinal kyphoscoliosis patients who underwent PVCR without anterior support applied was 1.8% (3/167). Evoked potential monitoring could not detect the occurrence of POD. POD in Yang's type A severe spinal kyphoscoliosis after PVCR could be ascribed to spinal cord kinking and DRG injury.
The impact of general practice team composition and climate on staff and patient experiences: a systematic review
Authors: Abrams Ruth , Jones Bridget , Gage Heather
Published: July 2023

Background

Recent policy initiatives seeking to address the workforce crisis in general practice have promoted greater multidisciplinarity. Evidence is lacking on how changes in staffing and the relational climate in practice teams affect the experiences of staff and patients.

Aim

To synthesise evidence on how the composition of the practice workforce and team climate affect staff job satisfaction and burnout, and the processes and quality of care for patients.

Method

Four different searches were carried out between December 2021 and March 2022 using MEDLINE, Embase, Cochrane, CINAHL PsycINFO and Web of Science. PRISMA guidelines were followed and data were synthesised thematically.

Results

Eleven studies set in primary care were included, 10 from US integrated healthcare systems, one from Canada. Findings indicate that when teams are understaffed and work environments are stressful, patient care and staff wellbeing suffer. However, a good relational climate can buffer against burnout and protect patient care. Good team dynamics and team cohesion have a greater impact on job satisfaction and patient care coordination than team composition; stable team membership is also important. Better patient experiences are associated with female physicians. However, these same physicians are at higher risk of burnout.

Conclusion

Evidence regarding team composition and team climate in relation to staff and patient outcomes remains limited. Challenges exist when drawing conclusions across different team compositions and differing definitions of team climate. Future research may benefit from exploring the conditions that generate a productive team climate.
Exploring patient, informal carer and care professional perspectives to understand the key clinical and non-clinical care needs of those living with multiple long-term conditions (MLTC)
Authors: Simpson Glenn , Okamoto Ikumi , Morrison Leanne , Santer Miriam , Farmer Andrew , Dambha-Miller Hajira
Published: July 2023

Background

Multiple long-term conditions (MLTC) are the co-occurrence of two or more chronic long-term conditions. While numerous studies have examined health and social care needs associated with MLTC, there has been limited research exploring both clinical and non-clinical care needs of this patient cohort from a range of perspectives.

Aim

To explore patient, informal carer, and care professional perspectives to identify what are the key clinical and non-clinical needs for optimal care in people with MLTC.

Method

Semi-structured interviews were conducted with a representative sample of 29 patients, informal carers, and professionals, using video-link or telephone. Inductive reflexive thematic analysis was used to analyse and interpret the data.

Results

A range of clinical and non-clinical care needs were identified, including supporting patient self-management of conditions, informal carer involvement in care decisions, limited knowledge of MLTC among care professionals, and mental health and socioeconomic needs of individuals were emphasised as important to optimal care in MLTC.

Improvements to optimise care included: more personalised care interventions, improved care professional understanding of MLTC care needs, involvement of informal carers in care decisions and promoting patient self-management of conditions and increased consideration given to non-clinical care needs.

Conclusion

MLTC patients often have a complex range of clinical and non-clinical care needs. This requires a holistic and coordinated care approach, enabling care to be tailored to personal care needs of individuals with MLTC.
EarLy Surveillance for autoimmune type 1 diabetes — paediatric screening in the UK
Authors: Quinn Lauren , Dias Renuka , Garstang Joanna , Greenfield Sheila , Richter Alex , Narendran Parth , Shukla David
Published: July 2023

Background

Children with pre-symptomatic type 1 diabetes can be identified through testing for circulating islet autoantibodies. Identifying children at risk reduces the rates of diabetic ketoacidosis at presentation and allows participation in clinical trials for type 1 diabetes prevention.

Aim

The Early Surveillance for Autoimmune diabetes study (ELSA) is exploring feasibility and acceptability of UK paediatric general population screening.

Method

The ELSA study runs from July 2022 to August 2024 and aims to recruit 20 000 children aged 3–13 years. ELSA is screening for islet autoantibodies via dried blood spot (DBS) and subsequent staging via oral glucose tolerance testing. ELSA is exploring feasibility and acceptability of UK paediatric general population screening.

Results

At the time of writing, 2582 children have been consented to the study. In the preliminary beta version (July–October 2022), there were 59 expressions of interest, 37 children consented (63%) and 22 kits returned (59%). Of the consented children, 17 families were invited and 8 were passive recruits through friends/family. Reasons for not returning the kit included issue with home-testing (n=1) and concern about the lancet (n=1). One of the DBS kits screened positive (4.5%), but the serum confirmation did not detect autoantibodies. The study launched nationally via social media on 14 November 2022 (World Diabetes Day) leading to a surge in expressions of interest (n=3070). Of these, 2141 children were consented within 36 hours.

Conclusion

Social media has been an effective route to recruitment. Community outreach to schools and general practices will be implemented as this study evolves, to explore optimal recruitment modalities and acceptability.
Countering crimes and infractions committed by persons serving prison sentences in Mongolian prisons
Authors: Chuluunbaatar Batbold
Published: July 2023

The article describes the results of investigating the causes and conditions of crimes and infractions committed by convicts in Mongolian penitentiary institutions. The author describes the Mongolian penal system and analyses the specifics of crimes and infractions committed in the country over a fifty-year period. An increase in crimes related to illicit trafficking in drugs and psychoactive substances, as well as corruption and malfeasance are noted. Attention is drawn to the growing burden on penitentiary institutions and, as a result, the increase in crimes and infractions committed by convicts. The main measures for preventing both individual and group encroachments of convicts on the activity of penitentiary institutions are shown. The effectiveness of the implemented measures is evaluated, promising directions for reducing the criminalization of convicts and preventing recidivism are identified. Their preconditions and peculiarities of countermeasures are explained, as well as the efficiency of prevention.

Methodology, methods. The conclusions made during the research process are the result of using various scientific methods, in particular, analysis and synthesis, as well as systematic and comparative methods of scientific cognition.

Results. The research analyses the organization of Mongolia’s penal system, as well as statistical data on crimes and infractions committed by persons sentenced to imprisonment. The need for a comprehensive and multidisciplinary study of the causes of crimes and infractions is substantiated, and proposals for reducing the level of penal offences are outlined.
Determinants of Motivation on Consumer Adoption of Healthcare Applications
Authors: - KEERAT KAUR KHALSA , - SUNETRA SAHA
Published: July 2023

With the sudden shift towards the digital era, technology is now incorporated in nearly all aspects of human life. The change in behavior of users is not easy and is generally bound by a lot of motivational factors to influence users to go for a particular product. mHealth is a term recognized by the world health organization and it is a simple term for the incorporation of technology in the world of health care. This study aims at understanding the determinants of motivation behind the adoption of mHealth by a large population of our country. VROOMs expectancy model of motivation was used where respondents were asked about the 3 components of the model that is, expectancy, instrumentality and valence and the factors of motivation were understood. A total of 181 respondents were taken for this study and factors such as easy, fast delivery and 24x7 availability of medical help emerged as the key factors attracting users to choose mHealth or e-pharmacies over offline stores.
Phytotoxic Effect of Elaeagnus Latifolia (L) on Growth and Metabolism of Synedrella Nodiflora (L)
Authors: - Suraj S. Patil. , - Sujay D. Hodage. , - Dilip N. Mohite. , - Nitin K. Patil. , - Dr. T. G. Nagaraja.
Published: July 2023

The present investigation deals with impact of powdered leaf and stem residue of Elaeagnus latifolia L on weed Synedrella nodiflora L, which adversely affected the growth and metabolism. The residues of leaf and stem greatly influenced the growth parameter including production of leaves and branches after 15 and 30 days of sowing. Meanwhile the biochemical constituents such as total Chlorophylls, polyphenol content, protein and carbohydrate levels were greatly comprehensively reduced in leaves and stem of Synedrella nodiflora L after 15th,30th and 45th days after sowing, as compared to control. Therefore, these allelochemicals may retard growth and metabolism of Synedrella nodiflora L hence residues may be considered as bio-herbicide or eco-friendly herbicide.
Importance of Quality Education and Sustainable Development: An Indian Perspective
Authors: - Manoj Kumar Yadav
Published: July 2023

Education is like a basic necessity if we really want to make our planet environment-friendly and liveable for all. But quality education work as a catalyst for overall socio-economic and environmental development in any country. The concept of sustainable development has become a buzzword and without practicing it we cannot make this world sustainable economically, socially and environmentally. We cannot ignore the impact of climate change in anyway. India is now the most populous county in the world and its rapid industrialization, and materialistic lifestyles are posing a serious threat to sustainable development and environmental sustainability. Sustainable development policy tries to balance contradicting factors like economic development and climate change. SDG 4 strongly promotes to ensure Inclusive and equitable quality education. NEP (2020) has given a special focus on SDG 4 to ensure quality education in the country. Therefore, this article mainly discusses the role of quality education and NEP (2020) in achieving the goals of sustainable development and also emphasizes the importance of quality education in promoting sustainable development.
Effectiveness of Physiotherapeutic Interventions in a Post-Surgical Burn Patient - A Case Study
Authors: - Akanksha Nagar , - Sandeep Kumar , - Smati Sambyal
Published: July 2023

Introduction: Burn injuries are a major cause of morbidity and mortality in children. In India, the figure constitutes about one-fourth of the total burn accidents. Burn injuries can lead to scar tissue formation that further leads to functional limitations. Each paediatric burn case is unique, and a tailored approach is necessary for effective physiotherapy management. Therefore, the aim of this study is to explore the effects of physiotherapeutic interventions on range of motion, scar quality, pain and anxiety in post-surgical patient with a 20% second degree superficial partial-thickness flame burn.
Case Presentation: A 9-years old female patient, admitted to Plastic surgery and Burn Unit, was recruited for the study. She had undergone skin grafting following the burn. Physiotherapeutic interventions were provided in two phases over 8 weeks, including exercises adjunct with ultrasound therapy and application of transcutaneous electrical nerve stimulation for 8 weeks lasted the treatment session for 60 minutes. The outcome measures used in this study were range of motion of following joints- right shoulder, right elbow joint and left shoulder joint, scores of Vancouver scar scale and scores of specific burn pain and anxiety scale. The assessments were taken at pre intervention 0 week, mid-intervention 4th and 8th week post intervention.
Results and Conclusion: The findings of this study showed improvements in ROM of affected joint- right shoulder joint and right elbow joint and left shoulder joint, scar tissue quality, pain and anxiety reduction. Further research is needed to establish the relationship and determine optimal interventions for burn subjects. This study concluded the effectiveness of physiotherapy in burn rehabilitation.
Modelamiento y simulación de sistemas de enfriamiento por absorción empleando energía solar, según TRNSYS 17
Authors: Antonio Romero José , Del Cisne Loján María , Yerovi Karla , Yajaira Romero Andrea , Elías Gonzalez Juan
Published: July 2023

Este artículo presenta el modelamiento y la simulación de un sistema de enfriamiento por absorción empleando energía solar como alternativa para la climatización de edificaciones en climas cálidos y húmedos como es el laboratorio del Centro Experimental de Investigación y Producción Amazónica de la Universidad Estatal Amazónica. Las simulaciones fueron realizadas empleando el programa Transient System Simulation Tool (TRNSYS 17). El sistema modelado y simulado está conformado por los siguientes elementos fundamentales: colectores solares de tubos al vacío, un tanque de almacenamiento de agua caliente, un sistema auxiliar de calentamiento, una máquina de absorción, y una torre de enfriamiento. Los resultados muestran que el sistema más adecuado emplearía un área de captación de energía solar de 100 m² que será entregada con 35 colectores de tubos al vacío marca Factsheet Olymp Sunstar HP 65/20 con una inclinación de 10° orientados al norte, un volumen de almacenamiento de agua caliente de 3,2 m³ y un flujo de agua en los colectores de 3 000 kg/h, y una máquina de absorción Yazaki de simple efecto de Bromuro de Litio y Agua de 20 kW o 5,68 toneladas de refrigeración (TR).
Generalidades de la infección por virus sars-cov-2 en recién nacidos
Authors: Benítez Aguilar Iliana , Castillo López. Dorayis , Ramirez Vazquez Erismel
Published: July 2023

Introducción: La enfermedad por coronavirus 2019 (COVID-19) es una infección de las vías respiratorias causada por un nuevo coronavirus (SARS-CoV-2, abreviación de Coronavirus 2 del Síndrome Respiratorio Agudo Grave), que se reconoció por primera vez en Wuhan, provincia de Hubei, China, en diciembre de 2019 y se diseminó rápidamente lo que llevó a que el 11 de marzo de 2020 la OMS la declarara una pandemia. Los grupos de población con mayor riesgo de padecer la enfermedad incluyen a las personas de edad avanzada, pacientes con enfermedades crónicas o problemas de inmunidad. Los recién nacidos no están exentos de contraer la enfermedad por COVID-19 debido a  la inmadurez inmunológica que los caracteriza. Objetivo: Recopilar información relacionada con la infección por SARS-COV-2 COVID-19 en recién nacidos. Método: Se realizó una revisión bibliográfica sobre el tema a través de búsquedas en diferentes bases de datos bibliográficas: Medigraphic, google chrome, Scielo fueron consultadas 43 referencias bibliográficas y seleccionadas 26 de ellas.  Resultados: La información se estructuró en: Generalidades; epidemiologia de la COVID-19 en recién nacidos; manifestaciones clínicas, exámenes complementarios; alimentación durante la COVID-19 sospechada o confirmada; tratamiento, criterios de egreso, vacunación, criterios de egreso  y seguimiento al egreso.  Conclusiones: Se insiste en la prevención como base fundamental para evitar el contagio por SARAS-COV-2 en los recién nacidos y la importancia de mantener la lactancia materna como principal alimento para los recién nacidos sospechosos o confirmados con la infección por el virus. Se conoce que la infección por el virus SARS-COV-2 en los recién nacidos evoluciona de forma leve no obstante son pacientes de alto riesgo debido a la inmadurez inmunológica que los caracteriza. Los protocolos de actuación e informaciones sobre el tema están sujetos a cambios debido a que la enfermedad por coronavirus SARS-COV-2 aún es objeto de estudio.
Multiple myeloma
Authors: Weerawansa Prasanna
Published: July 2023

No abstract available
High Tuberculosis density incidence rate in Matched Unrelated Allogeneic stem	cell transplantation recipients in the state of São Paulo, Brazil
Authors: Nóbrega Litvoc Marcelo , Costa Silvia F , Eudes Leal Fabio , Boldim Ferreira Diogo , Banks 	Ferreira Lopes Max Igor , Capuani Ligia , Geraldo Rocha Vanderson
Published: July 2023

Background: There is limited data regarding Tuberculosis in hematopoietic stem cell transplantation (HSCT), especially in endemic countries.
Objectives: We aimed to describe the density incidence rate and standard incidence ratios
(SIR) of tuberculosis in matched  unrelated allo-HSCT.
 
Methods: We conducted a retrospective cohort study including all patients who underwent
Matched unrelated allo-HSCT from 2007-2016 in the state of São Paulo, Brazil. Tuberculosis
In this population was identified by record linkage between the national HSCT database
(REREME)  and  the  São  Paulo  State  Tuberculosis  Control  Program  database.
Results Five tuberculosis cases(03 males) were identified and described among 1,223 allo-HSCT. The average age was 25 years, and the estimated time between HSCT and Tuberculosis diagnosis was 376 days. Density incidence rate and standardized incidence ratios(SIR) were compared between matched unrelated donor allo-HSCT and the Tuberculosis
database of the São Paulo state (172,925 cases). Considering 2,718 patients/year, the
density incidence rate in the allo-HSCT population was 183 cases/100.000 patients/year
(SIR:4.9 and 95% CI 1.8-11:), much higher than the average rate for the whole population
in  the state  of  São  Paulo for the  same period:  38.8/100.000  inhabitants.  
Conclusion; Allo-HSCT patients are highly vulnerable to tuberculosis disease, in our study
almost five times higher   than  in  general   population.   Improving  epidemiological   data  and  a  better surveillance system are essential in tackling this critical condition, especially in endemic countries.
Primary animal experiment to test the feasibility of a novel Y-Z magnetic hepatic portal blocking band
Authors: Zhang Miao-Miao , Li Chen-Guang , Xu Shu-Qin , Mao Jian-Qi , Ren Yu-Xiang , Zhang Yu-Han , Ma Jia , Shi Ai-Hua , Lyu Yi , Yan Xiao-Peng
Published: July 2023

Obstructive jaundice (OJ) is a common problem in daily clinical practice. However, completely understanding the pathophysiological changes in OJ remains a challenge for planning current and future management. The effects of OJ are widespread, affecting the biliary tree, hepatic cells, liver function, and causing systemic complications. The lack of bile in the intestine, destruction of the intestinal mucosal barrier, and increased absorption of endotoxins can lead to endotoxemia, production of proinflammatory cytokines, and induce systemic inflammatory response syndrome, ultimately leading to multiple organ dysfunction syndrome. Proper management of OJ includes adequate water supply and electrolyte replacement, nutritional support, preventive antibiotics, pain relief, and itching relief. The surgical treatment of OJ depends on the cause, location, and severity of the obstruction. Biliary drainage, surgery, and endoscopic intervention are potential treatment options depending on the patient's condition. In addition to modern medical treatments, Traditional Chinese medicine may offer therapeutic benefits for OJ. A comprehensive search was conducted on PubMed for relevant articles published up to August 1970. This review discusses in detail the pathophysiological changes associated with OJ and presents effective strategies for managing the condition.