bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical and Immunological Parameters in the Diagnostics of Asthenic Syndrome in Patients with Chronic Heart Failure
Authors: Zozulya S. A. , Volel B. A. , Fomicheva A. V. , Andreev D. A. , Otman I. N. , Klyushnik T. P.
Published: January 2023

Background: the significance of the asthenic syndrome as one of the most distressing symptoms affecting the clinical outcome of chronic heart failure (CHF), and insufficient understanding of the pathophysiological aspects of asthenia determines the need to study the clinical and biological features of this syndrome in cardiac pathology. Objective: to determine of a number of inflammatory and autoimmune blood parameters in patients with CHF associated with asthenic disorders in comparison with hypertensive disease in relation to clinical and gender-age characteristics of patients. Patients and methods: 62 patients with CHF (study group; 64.4 ± 9.7 years) and 50 patients with hypertensive disease (HD) (comparison group; 55 ± 9.7 years) were examined. Somatic examination included consultation with a cardiologist. Psychometric assessment was performed using the MFI-20 scale and the MLHFQ questionnaire. In patients' blood, leukocyte elastase (LE) activity, α1-proteinase inhibitor (α1-PI), leukocyte inhibitory index (LII), concentration of CRP, IL-6, and levels of antibodies to S-100B and myelin basic protein were determined. Results: patients with CHF characterized by more pronounced manifestations of all dimensional asthenic disorders compared to patients with HD. The deterioration of CHF patients' quality of life was accompanied by the aggravation of asthenic symptoms on all subscales of the MFI-20 scale. In patients with CHF and HD, multidirectional changes in the leukocyte inhibitory index and significant quantitative differences in other immune parameters compared with the normative values were detected. CHF associated with asthenia was characterized by decreased activity of the blood proteolytic system (decrease in LII), a significant increase in the concentration of IL-6, CRP and antibodies to S-100B in the blood of patients compared to comparison group. Negative correlations between LE activity and several dimensions of the MFI-20 scale, and positive correlations between the severity of general asthenia, patient age, and IL-6 and CRP concentrations indicate the involvement of inflammation in the pathophysiology of asthenic disorders in the cardiac pathology discussed. Conclusion: low activity of blood proteolytic system and high level of inflammation are unfavorable factors in the development of asthenia in chronic heart failure. Qualitative and quantitative features of the spectrum of immunological parameters in patients with CHF are correlated with clinical and genderage characteristics and reflect the severity of both cardiological changes and asthenic symptoms.
Clinical and neuroimaging study of patients with Parkinson’s disease using transcranial sonography and neuromelanin-sensitive magnetic resonance imaging
Authors: Moskalenko A. N. , Chechetkin A. O. , Filatov A. S. , Fedotova E. Yu. , Konovalov R. N. , Illarioshkin S. N.
Published: January 2023

Background. Parkinson’s disease (PD) is one of the most common neurodegenerative diseases and aff ects 1% of the population above 60 years. The leading pathological features of PD include degeneration of neuromelanin (NM) containing dopaminergic neurons and iron deposition in the substantia nigra (SN) of the midbrain. Various neuroimaging methods sensitive to NM and iron can be clinically important for diagnosing and monitoring disease progression. Examples of such neuroimaging methods include transcranial sonography (TCS) and neuromelanin-sensitive magnetic resonance imaging (NM-MRI) fi rst and foremost.

Aims. To compare the diagnostic signifi cance and eff ectiveness of TCS and NM-MRI in diff erentiating patients with PD from the norm and to elucidate the magnetic resonance- (MR-) morphological representation of the hyperechogenicity (HE) on midbrain during TCS by NM-MRI.

Material and methods. 40 patients with PD were included in the main group, and 20 healthy volunteers of gender and age comparable with the main group were included in the control group. In the case of HE detection during TCS, this area was manually traced and automatic calculated. NM-MRI images were pre-processed using image processing program Image-J (USA) with subsequent automatic calculation of SN area. Based on the data obtained, clinical, demographic and neuroimaging correlations were estimated.

Results. The sensitivity and specifi city of TCS in diff erentiating PD from the norm were 70 and 100% respectively, the sensitivity and specifi city of NM-MRI were 90.0 and 92.5% respectively. An analysis of the relationship between the HE area and the area of the SN according to NM-MRI data on the ipsilateral side showed a noticeable inverse correlation (for the right side: ρ = –0.606, p < 0.001; for the left side: ρ = –0.550; p < 0.001). Thus, in the case of an increase in the HE area, a decrease in the area of SN measured using NM-MRI is expected.

Conclusion. TCS and NM-MRI are reliable biomarkers allowing highly eff ective diff erentiation of PD from normal. The pathophysiological and neuroimaging correlates of PD changes in neurodegenerative process remain not completely clear and require further clarifi cation in multicenter prospective studies.
Evaluation of the effectiveness of migraine therapy using functional resting MRI with course rhythmic transcranial magnetic stimulation
Authors: Trufanov A. G. , Markin K. V. , Frunza D. N. , Litvinenko I. V. , Tarumov D. A. , Kuznetsova E. V. , Efimtsev A. U. , Odinak M. M.
Published: January 2023

Introduction. In the context of the search for new migraine therapy options, strict control of their eff ectiveness by means of objective examination methods is required.

Objective. Objective assessment of the eff ectiveness of TMS in patients with migraine on the basis of functional magnetic resonance imaging (fMRI) data.

Material and methods. Resting-state fMRI before and after a fi ve-day course of TMS of the junction of the inferior frontal and temporal lobes bilaterally was performed in 19 patients with migraine. Changes in functional connectivity (FC) of the main neuronal networks of the brain, as well as clinical parameters of pain and quality of life of the patients were assessed before and after the course of TMS.

Results. A decrease in pain intensity and anxiety scores, as well as a decrease in the number of acute pain medications taken, was observed against the background of the therapy. Changes in FC aff ected three main networks: the default mode network, the salience and visual networks. At the same time, decreased effi cacy of therapy was noted in patients with higher severity of depressive symptoms and presence of neuroimaging criteria of depression.

Conclusion. The study suggests the effi cacy of TMS in patients with migraine based on neuroimaging criteria. It is worth paying special attention to the presence of depressive symptoms in migraine patients.
Virtual reality as a personifi cation method for training memory and attention (non-systematic review)
Authors: Protasova L. M. , Zapekin S. G. , Shnaider G. V. , Naumov Z. A. , Kamenskih E. M. , Titova M. A.
Published: January 2023

One of the latest achievements in the field of medicine is the introduction into practice of technologies using computerized training and training in Virtual Reality (VR), which create new opportunities for prevention, as well as treatment for people suff ering from various cognitive impairments.

Purpose of the study. The aim is to investigate classical (conventional), computerized and VR training using neural interfaces focused on the prevention and rehabilitation of functional changes in higher nervous activity.

Methods. In March 2022, a search was made for scientifi c full-text publications using the electronic databases of the RSCI, PubMed and Google Scholar. The following keywords and their combinations were used for the query: “dementia”, “aging” and “virtual reality”. Articles of interest for this review had to be peer-reviewed, published no later than 2015, and written in English or Russian.

Results. The key methods of non-drug interventions in people suff ering from various cognitive impairments, the advantages and disadvantages of the techniques used were considered. It also shows the main advantages of VR technology as a simple, safe and eff ective tool. VR has great potential for personalized cognitive trainings.
Phenotyping of embolic cryptogenic stroke based on ultrasound diagnosis and determination of serum concentration NT-proBNP
Authors: Mekhryakov S. A. , Syromyatnikova L. I. , Kulesh A. A. , Shestakov V. V. , Karakulova Yu. V.
Published: January 2023

Determining the potential mechanisms underlying cryptogenic ischemic stroke is essential to guide diagnostic discovery and personalize secondary prevention.

Purpose is to study the phenotypes of embolic stroke of undetermined source (ESUS) based on ultrasound diagnosis and determination of the serum concentration of pro-natriuretic N-terminal peptide B-type (N-Terminal Pro-brain Natriuretic Peptide, NT-proBNP).

Materials and methods. 141 patients with ESUS were examined. In addition to the standard examination aimed at fi nding the cause of stroke, the functional characteristics of the left atrium were assessed using the emptying fraction (left atrial emptying fraction, LAEF) and the functional index (left atrial function index, LAFI), and the concentration of NT-proBNP in blood serum was also measured.

Results. The most common potential sources of embolism were atherosclerotic plaques in the stroke-associated carotid artery with stenosis in 30–49% (31.9% of patients) and atrial cardiopathy with a decrease in LAEF < 51.8% (24.8% of patients). An analysis of combinations of potential sources showed that 46.1% of patients had a negative phenotype, 21.3% of patients had a cardiac phenotype, 19.1% of patients had an atherosclerotic phenotype, and 13.5% of the examined patients had a mixed phenotype. Patients with a cardio-atherosclerotic phenotype diff ered from patients with a negative phenotype by higher disability on the Rankin scale at discharge from the hospital.

Conclusion. The main potential embolic sources in patients with ESUS are non-stenosing carotid atherosclerosis and atrial cardiopathy with decreased LAEF. Cardiac and atherosclerotic phenotypes are determined in a quarter of patients, a mixed phenotype is found in every seventh patient, while in almost half of the patients no sources of embolism are found.
Using of MRI-guided focused ultrasound treatment for Parkinson’s disease tremor. Clinical case and literature review
Authors: Dzhafarova M. Y. , Dzhafarov V. M. , Senko I. V. , Belousov V. V.
Published: January 2023

MRI-guided high-intensity focused ultrasound (MRgFUS) is a new emerging and promising procedure applied in a wide range of clinical fi elds in modern medicine. This innovative treatment method follows is an important step towards the ideal surgery of the future: non-invasive, targeted, safe, controlled, eff ective and ambulatory. Randomized studies show high effi cacy in the treatment of tremor for Parkinson disease and essential tremor. Safety is also having similar profi le with other surgical procedures and has a mostly transient character of complications. Such advantages as a non-invasive treatment, controlled eff ect and the safety profi le of the procedure made it popular in the treatment of movement disorders. This article demonstrates a clinical case of the fi rst using of MRgFUS for the treatment of Parkinson’s disease tremor at the Federal Center for Brain Research and Neurotechnologies of the Federal Medical and Biological Agency of Russia in Moscow. The 54-year-old patient with Parkinson disease, 2 Hoehn–Yahr, admitted to our hospital. Severe tremor of right upper extremity impaired his life. Neurosurgical procedure was considered due to medication failed. Patient underwent focused ultrasound thalamotomy with totally tremor relief. No additional neurological impairment was noted, only bradykinesia and rigidity were improved. Patient discharged on 3rd day after the procedure.

Conclusions. MRgFUS is an innovative surgical procedure. Advantages of these methods such as non-invasive manner, controlled, safety allowed to be priority procedure for patients with unilateral tremor.
IMPLEMENTATION OF LEGAL PROTECTION AND EMPOWERMENT FOR FARMERS IN CIBODAS VILLAGE BASED ON LAW NUMBER 19 OF 2013 ON THE PROTECTION AND EMPOWERMENT OF FARMERS
Authors: Purnamasari Galuh Candra , Hestyara Aulia
Published: January 2023

This study examines two problems. First, the effectiveness of Law Number 19 of 2013 on the Protection and Empowerment of Farmers in providing legal protection and empowerment for farmers. Second, the role of the Cibodas village government as a party that offers legal protection and empowerment to farmers. The breeders in this study focused on dairy farmers. This study used a sociological juridical approach. The data were obtained through field and library data, then analyzed using qualitative methods without applying a systematic model or statistical formulation. This study took the research location in Cibodas Village, Lembang District, West Bandung. The conclusions drawn from this study are; first, there are still obstacles related to the effectiveness of legal protection and empowerment of farmers in Cibodas village seen from legal factors, facilities and infrastructure factors, and cultural factors. Second, the Cibodas Village government's role in providing legal protection and empowerment for breeders remains limited. In contrast, the Animal Husbandry Department of West Java and the Cattle Breeders Cooperative of North Bandung are taking on more responsibilities in presenting legal protection and empowerment for farmers in Cibodas Village.
Analysis of Article 69 of Law Number 8 of 2010 concerning Prevention and Eradication of the Crime of Money Laundering in the Perspective of Legal Certainty
Authors: Charles Iwan Roy
Published: January 2023

The problem that has been an obstacle for the prosecutor's office to enforce money laundering offenses is the evidence which constitutes "multiple and related offenses", which means that the offense will not exist if there are no other offenses as the origin of the offense. Article 2 of Law Number 8 of 2010 has stated the types of predicated crimes in money laundering. The crime of money laundering is included in the qualification of a special crime, not a general crime. A general crime is a crime regulated in the Criminal Code (hereinafter abbreviated to the Criminal Code) and is an act of a general nature, Type ResearchThis research uses normative legal research. Researchers found The analysis of Article 69 of Law No. 8 of 2010 concerning the prevention and eradication of the crime of money laundering in the perspective of legal certainty is debatable because Article 69 does not need to have a proven main crime to prosecute and criminalize the perpetrators. Ideally, evidence in handling cases of money laundering in conducting investigations, prosecutions, and examinations in court is not required to prove the original crime.
Indigenous Community Existence In Indonesia's Constitution
Authors: Akmal Zainul , Lestari Rika
Published: January 2023

Law enforcers in their thoughts and behavior in enforcing the law improve the existence of indigenous peoples and their traditional rights. This can be proven by the process of law enforcement starting from the police, prosecutor's office to the court that gave bad decisions. This conceptual study aims so that everyone can understand the meaning of indigenous peoples, the existence of indigenous peoples in the Indonesian constitution, and recognize and respect the existence of indigenous peoples so that justice can be upheld for indigenous peoples. Based on the study it can be concluded that indigenous peoples are people who have territory, the government, law and citizens are independent and have existed since the Indonesian state was not yet formed and the existence of indigenous peoples in the Indonesian constitution has been recognized since Indonesia's independence until now whose regulations have been clearer than previous constitutions.
The Customary Government System in Koto Tuo Baserah Kuantan Singingi
Authors: Putra Setia
Published: January 2023

The objectives in this study are; to find out the customary government system and  the role of customary devices in Koto Tuo Baserah Kuantan Singingi. This method of research is sociological. The leader in Koto Tuo is called Datuk Bisai or Datuk Penghulu with the title Datuk Godang. Meanwhile, the top tribal leaders in the village of Kuansing are called mamak soko. The are four tribes in Kuantan Singingi. They are Tigo Kampung entitled Jolak Samano, Limo Kampung titled Datuk Bandaro, Cermin titled Godang, and Melayu titled Datuk Paduko. In Koto Tuo regency is guided by 4 traditional stakeholders, namely: Penghulu (mamak soko / chieftain), Monti, Dubalang, and Malin, an Islamic religious figure. Then 3 Traditional Leaders in one tribe have representatives, each tribe is divided into 3 Jurai (Departments). The role of Datuk Penghulu and other traditional stakeholders in Koto Tuo is still partly ongoing. However, there are shifts in the role of traditional stakeholders in village government. They are: the role of traditional stakeholders in terms of marriage, divorce, privately owned land, livestock, fields, civil cases and criminal cases. And the role of traditional stakeholders in village government that has not shifted is in terms of customary land and heritage treasures. The Factors causing the shift in the role of indigenous stakeholders in village government are : globalization, contact with other cultures, modernization, community dissatisfaction with certain areas, an increasingly educated, heterogeneous and growing population.
TITIK AWAL PEMBERANTASAN TINDAK PIDANA KORUPSI
Authors: Handoko Duwi
Published: January 2023

Corruption in Indonesia has been very widespread in society and continues to increase every year. Increased uncontrolled corruption will bring disaster not only to the life of the national economy but also to the life of the nation and state in general. To achieve the purpose, which is to find out and analyze the solution to eradicate corruption and the eradication of corruption should begin, normative legal research methods are determined with the nature of descriptive research. The solution to eradicating corruption can be done by strengthening the faith and culture of shame, a proper payroll system, system, bureaucracy, and anti-corruption and anti-corruption laws, reversed proof, severe punishment, strict and indiscriminate law enforcement, and collective awareness and public control. Departing from the history of the term corruption, it is only known in criminal legislation outside the book of criminal law, namely since the existence of the Military Rule Number Prt/PM/06/1957 dated April 1, 1957 concerning Eradication of Corruption. Then there is no harm in eradicating corruption beginning with the delegation of duties, functions, authorities, and things that are not contrary to other laws in the eradication of corruption to the military, which at this time can be prosecuted in fighting enemies of countries that are no longer involved in active politics, as well as proof of service to a country that is attacked by a disease that is difficult to treat.Key words: Corruption, State Enemy, Military
PENAWARAN JASA NOTARIS MELALUI WEBSITE
Authors: Halim Ronald
Published: January 2023

Penelitian ini bertujuan untuk ; 1) penggunaan website oleh notaris ditinjau dari Pasal 4 angka 3 Kode Etik Notaris; 2) pengawasan terhadap penggunaan website dalam profesi jabatan notaris.Tipe penelitian ini adalah penelitian Normatif- Empiris. Data dikualifikasi sebagai data primer dan sekunder. Data primer diperoleh melalui wawancara, dan data sekunder diperoleh melalui studi literatur. Data yang dikumpulkan kemudian diolah dengan menggunakan pendekatan analisis kualitatif.Hasil penelitian ini menunjukkan bahwa: 1) Penggunaan Website oleh Notaris ditinjau dari Pasal 4 angka 3 Kode Etik Notaris adalah bentuk pelanggaran kode etik jika dalam website tersebut mempromosikan diri, yang dapat diartikan bahwa mengIklankan diri sebagaimana yang dimaksud dalam Pasal 4 kode etik notaris. Dalam iklan tersebut ada kata/kalimat dari Notaris yang bersangkutan untuk menawarkan kepada masyarakat agar menggunakan jasa notaris. 2) Pengawasan terhadap penggunaan website dalam profesi jabatan Notaris merupakan wilayah dari dewan kehormatan yang harus mencari bukti terlebih dahulu apakah seorang notaris dalam menggunakan website benar-benar telah melakukan pelanggaran terhadap aturan Kode Etik. Hal ini tentu saja penting karena penggunaan website sangat rentan dengan perspektif apakah benar-benar telah terjadi promosi dalam penggunaan website oleh notaris.
REGULASI PERLINDUNGAN HUKUM SEBAGAI WUJUD PENINGKATAN PENDAYAGUNAAN PEMBERANTASAN KORUPSI DI INDONESIA
Authors: Siregar Vivi Arfiani , Mukhlis Indra
Published: January 2023

AbstractVarious problems related to corrupt practices. Corruption is not new and has nothing to do with halal and haram law, it has been around for a long time and made successful adjustments to every change of rules in this country. The type of research used is normative legal research (library research). The purpose of this research is to find out the principles, norms of laws and regulations, court decisions and doctrines in assessing corruption. Corruption is categorized as a systemic crime that must be eradicated systematically, the problem of corruption includes legal substance, legal structure, and legal culture Keyword : the field of law, Corruption, legal structure, legal substance, legal culture AbstrakBerbagai masalah yang berkaitan dengan praktik korupsi. Korupsi bukanlah hal baru dan tidak ada hubungannya dengan hukum halal dan haram, sudah ada sejak lama dan membuat penyesuaian berhasil setiap perubahan aturan di negara ini. Jenis penelitian yang digunakan adalah penelitian hukum normatif (library research). Tujuan penelitian adalah mengetahui asas-asas, norma dari peraturan perundang-undangan, putusan pengadilan serta doktrin dalam menilai korupsi. Korupsi dikategorikan sebagai kejahatan sistemik yang harus diberantas secara sistematis, masalah korupsi termasuk substansi hukum, struktur hukum, dan budaya hukum Kata Kunci: bidang hukum, Korupsi, struktur hukum, substansi hukum, budaya hukum.
Pelaksanaan Perjanjian Tertutup (Tying Agreement) Oleh PT Pelabuhan Indonesia II (PERSERO) Pada Area Konsesi Pelabuhan Dalam Perspektif Hukum Persaingan Usaha
Authors: Elevenday Kahfiarsyad Julyan
Published: January 2023

This study aims to find out about how the monopoly activities including how the implementation of a tying agreement conducted by PT Pelabuhan Indonesia II (Persero) as a SOE in the perspective of Competition Law. This study is conducted by analyzing the consideration of judges as stated in the Supreme Court of Republic Indonesia Decision No. 302 K/Pdt. Sus-KPPU/2014 and North Jakarta District Court Decision No. 1/Pdt/KPPU/2015/PN Jkt.Utr. The results of this study indicate that the monopoly activities conducted by PT Pelabuhan Indonesia II (Persero) in its concession area are a monopoly by law as stated in Article 50 a Law Number 5 Year 1999 concerning The Prohibition of Monopolistic Practices and Unfair Business Competition because the monopoly activity referes to Law Number 17 Year 2008 concerning Shipping which regulates that to conduct commercial activities at the port needs a concession agreement that given by the port operator. The implementation of a tying agreement made by PT Pelabuhan Indonesia II (Persero) is not against the Law Number 5 Year 1999 concerning The Prohibition of Monopolistic Practices and Unfair Business Competition because if a rule of reason approach is used in the case, then the positive impact resulting from the implementation of tying agreement is greater that the negative impact. Keywords: Tying Agreement, Monopoly, State Owned Enterprise, Port, Business Competition
Internalisasi Religiusitas Siswa Kelas V SD Melalui Kegiatan Membaca Asmaul Husna
Authors: Hamidah Rifa Dwi , Markhamah Markhamah
Published: January 2023

The habit of reading asmaul husna is one of the routine activities at SDN 1 Panusupan to instill religious values in students. This study aims to describe (1) the implementation of the teacher's method in the habit of reading Asmaul Husna and (2) the internalization of religious values in fifth grade students through habituation activities to read Asmaul Husna. The research method used is descriptive qualitative method with the type of case study research. Data collection techniques carried out include observation, interviews, and documentation. While the data analysis technique is carried out with the following steps: data collection, data reduction, data presentation, and drawing conclusions or verification. The research subjects were PAI teachers at SDN 1 Panusupan and fifth grade students at SDN 1 Panusupan. The results of the research found include, (a) the implementation of the teacher's method in the habit of reading Asmaul Husna, namely the classical method, individual method, and drill method and (b) internalization of religious values through the habit of reading Asmaul Husna is in the form of instilling the learning of faith and morals so as to develop students' personalities who have good personalities, have the potential for piety, and emotional intelligence.��
KONTRIBUSI ARISAN ONLINE DALAM MEMENUHI GAYA HIDUP MAHASISWA MENURUT SUDUT PANDANG EKONOMI ISLAM (Studi Kasus Pada Kelompok Arisan Mahasiswa Fakultas Ekonomi Dan Bisnis Islam Universitas Islam Negeri Sumatera Utara)
Authors: Alamsyah Adam , Sudiarti Sri , Rahma Tri Inda Fadhila
Published: January 2023

The progress of the development of life in Indonesia affects the lifestyle, especially students. Student, someone who demands education at higher education, has many necessities of life to fulfill his studies and daily life. Online arisan is an alternative for students to save money to fulfill their daily needs. This study aims to see how to see members who are online arisan, see which ones contribute to online arisan in fulfilling student lifestyles, and see a review of Islamic economics on online social gathering activities in the Islamic economics faculty of the State Islamic University of North Sumatra. The research method used a qualitative approach with data techniques, namely primary data and secondary data. Research subjects, the owner of the arisan and (9) members of the online arisan. Data techniques are premier data and secondary data. The data analysis methods used in the study were data reduction, data presentation, and conclusion drawing. The results of this study indicate that the lifestyle of students who take part in an online social gathering is classified as hedonistic, the contribution of online arisan to the arisan group is that there are many benefits obtained by members and an Islamic economic review of the online social gathering system is not allowed because it contains elements of usury in it.
KONTRIBUSI ARISAN ONLINE DALAM MEMENUHI GAYA HIDUP MAHASISWA MENURUT SUDUT PANDANG EKONOMI ISLAM
(Studi Kasus Pada Kelompok Arisan Mahasiswa Fakultas Ekonomi Dan Bisnis Islam Universitas Islam Negeri Sumatera Utara)
PENERAPAN MODAL SOSIAL PADA KEBERHASILAN PROGRAM PEMBIAYAAN BERBASIS KELOMPOK SEBAGAI UPAYA PENANGGULANGAN KEMISKINAN (STUDI KASUS PADA KOPERASI KELOMPOK HUMANIORA POKMAS MANDIRI, KANTOR CABANG DELI SERDANG)
Authors: Agustina Elvira
Published: January 2023

Materials/goods collateral is the biggest obstacle for MSMEs from poor families to obtain banking services and financing facilities.Social capital as a solution applied to group-based financing programs. This study attempted to analyze the application of social capital to the success of group-based financing programs in poverty alleviation efforts at The Humaniora Group Cooperation of Pokmas Mandiri at Deli Serdang Branch. The subjects of this study consisted of observer informants from The Humaniora Group Cooperation of Pokmas Mandiri, and the perpetrator informants namely members of the cooperation. This research is a field research using a qualitative approach. Data collections techniques used in this study were in-depth interviews, documentation, observation and review of literature. Based on the results, it was obtained that 1) The application of group-based financing programs has been modified to the conditions and needs of the society in Deli Serdang Regency, both from the social, economic and cultural of the society; 2) The application of social capital in the group-based financing program is considered very effective and efficient for The Humaniora Group Cooperation of Pokmas Mandiri in assessing and deciding the eligibility of members, through trust, participation, networks and social norms as assessment characteristics; 3) the success of group-based financing in reducing poverty can be seen through evaluation and direct interviews with members using family prosperity as indicators which is applied by The Humaniora Group Cooperation of Pokmas Mandiri, that the condition of members before and after getting a loan changes, not only increases the standard of living and economy of cooperation’s members, but also has an impact on their quality of life.
PENGARUH PROFITABILITAS, SOLVABILITAS, DAN OPINI AUDIT TERHADAP AUDIT DELAY UKURAN PERUSAHAAN SEBAGAI VARIABEL MODERATING (STUDI EMPIRIS PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BEI TAHUN 2015-2019)
Authors: Fadhillah Annisa , Satya Karya , Novietta Liza
Published: January 2023

This study aims to determine the effect of profitability, solvency and audit opinion on audit delay with compaby size as a moderating variable in manufacturing companies listed on the Indonesia Stock Exchange (IDX) for the 2015-2019 period. The sample in this study were 40 manufacturing companies listed on the Indonesia Stock Exchange in the 2015-2019 period. The data analysis technique used is multiple linear regression analysis with statistical data processing using SPSS version 20.0 data processing application.
The results of this study indicate that profitability and solvency have no effect on audit delay, however, audit opinion has been shown to have a positive and significant effect on audit delay. The MRA test results show that company size is able to moderate the relationship between the effect of profitability, solvency and audit opinion on audit delay.
KEBIJAKAN MONETER DAN IMPLIKASINYA TERHADAP PEMBANGUNAN EKONOMI DALAM PEREPEKTIF EKONOMI ISLAM
Authors: Putri Indah Aminah , Nasution Eza Okhy Awalia
Published: January 2023

Dalam sistem ekonomi Islam, peran pemerintah sangat krusial. Pemerintah mengambil sikap tegas tidak hanya pada penerapan Syariah oleh masyarakat umum, tetapi juga pada kebijakan ekonomi, seperti Pemenuhan kebutuhan dasar seperti sandang, pangan dan papan serta pendidikan dan kesehatan dengan tetap menjaga kerahasiaan . Kontrak kerja, kontrol nilai tukar dan pencegahan kenaikan harga. Inflasi. Untuk mencapai tujuan tersebut, pemerintah harus memiliki sumber daya yang cukup sesuai dengan tujuan dan sasaran yang telah ditetapkan untuk mendukung pertumbuhan ekonomi nasional. Dan satu-satunya aspek keuangan adalah uang. Kebijakan moneter adalah kebijakan yang dirancang untuk mengatur aliran uang dalam perekonomian guna menjaga stabilitas harga, inflasi terkendali, lapangan kerja penuh dan pertumbuhan ekonomi yang berkelanjutan. Penulis artikel ini mencoba untuk menyelidiki dampak kebijakan moneter dan hubungannya dengan perkembangan sistem ekonomi Islam dari perspektif teoritis dan konseptual. Kajian tersebut menyatakan bahwa tidak ada perbedaan peran kebijakan moneter baik dalam perspektif ekonomi Islam maupun modern, kecuali bahwa dalam perspektif ekonomi Islam pemerintah harus menjamin terpeliharanya nilai-nilai. pasar, seperti cadangan wajib dan pengaturan pembayaran bunga pinjaman, segala sesuatu yang dilakukan dalam bisnis ini dilakukan sesuai dengan prinsip Islam dan didasarkan pada praktik riba
Analisis Pola Tegasan untuk Menentukan Tipe Sesar Grindulu di Pacitan, Jawa Timur
Authors: Haryono Arif
Published: January 2023

Sesar Grindulu merupakan salah satu sesar aktif di Kabupaten Pacitan yang aktivitasnya telah beberapa kali menyebabkan terjadinya gempabumi. Posisinya yang memanjang dengan arah timur laut – barat daya seakan membelah Kabupaten Pacitan menjadi dua bagian, hal ini membuat Sesar Grindulu menjadi ancaman serius bagi masyarakat Pacitan. Salah satu langkah mitigasi bencana yang bisa dilakukan adalah dengan mengidentifikasi karakteristik Sesar Grindulu untuk mendapatkan informasi sebanyak mungkin. Dalam penelitian ini, tipe Sesar Grindulu ditentukan berdasarkan analisis pola tegasan menggunakan software Win-Tensor. Data masukan berupa dip dan strike adalah data sekunder hasil penelitian sebelumnya. Hasil analisis pola tegasan menunjukkan bahwa tegasan maksimum (σ1) merupakan gaya kompresi dan tegasan minimumnya (σ3) adalah gaya regangan, dimana  keduanya  berarah  horisontal.  Sedangkan  tegasan  menengahnya  (σ2) berarah  vertikal.  Pola  tegasan tersebut menunjukkan bahwa Sesar Grindulu termasuk dalam jenis sesar geser mengiri. Sementara itu, hasil proyeksi stereografi memperlihatkan bahwa tegasan utamanya  (σ1)  berarah  N17oE,  sedangkan  bidang sesarnya memiliki arah N60oE. Berdasarkan sistem sesar geser menurut konsep Moody dan Hill, Sesar Grindulu digolongkan ke dalam sesar geser orde pertama karena gaya kompresi terbesarnya menggerus pada sudut 43o.
Analisis Spasial Ordinary Kriging Persebaran Emas Berdasarkan Data Geokimia Permukaan Awak Mas, Sulawesi Selatan
Authors: Amalia Ani , Lepong Piter , Natalisanto Adrianus Inu
Published: January 2023

Kadar emas dapat diketahui dari hasil pengujian laboratorium dan atau dengan dilakukannya prediksi dengan teknik interpolasi Ordinary Kriging. Tujuan penelitian ini adalah untuk estimasi penyebaran kadar emas di Awak Mas Project menggunakan data sekunder dari hasil channel dan sampling data permukaan. Tahapan yang dilakukan adalah dengan memilih model semivariogram terbaik diantara semivariogram Spherical, Eksponensial, dan Gaussian dan menafsirkan pola penyebaran mineral emas menggunakan metode geostatistik ordinary kriging berdasarkan data sampling channel mineralisasi emas permukaan. Langkah pertama dalam pengolahan data adalah membuat semivariogram menggunakan software SGEMS dengan nilai nugget, sill, dan range masing-masing sebesar 0,01, 0,1, dan 600. Kemudian diinterpolasi menggunakan ketiga model untuk mendapatkan model terbaik berdasarkan nilai RMSE terkecil, model yang didapatkan adalah model Gaussian. Hasil dari penelitian ini adalah pola penyebaran mineral emas permukaan banyak ditemukan pada daerah barat laut (NW) dan barat daya (SW) yang dipengaruhi oleh struktur geologi
The importance of sperm diluents of different types of farm animals in the process of the cryopreservation
Authors: Korochkina E. , Moroz A.
Published: January 2023

Purpose:to systematize and analyze scientific information about diluents of sperm of farm animals in the process of its cryopreservation, taking into account specific features

Assisted reproductive technologies are extremely in demand in animal husbandry at the moment, especially with regard to artificial insemination. However, this technology is of priority importance if the sperm is stored for a long period when the sperm is cryopreserved. At the same time, numerous studies have established that the cryopreservation process causes adverse changes in germ cells, which leads to their damage or death, and partially irreversible damage to the morphological structures of cells occurs. To obtain high results from the use of frozen-thawed sperm, it is necessary to prevent damage to spermatozoa. In this regard, the use of sperm diluents is urgent. Each type of animal sperm has its own distinctive parameters volume, concentration, chemical composition, osmotic pressure, pH, etc. Therefore, it is difficult to develop a universal sperm diluent suitable for each type of animal.
Electrophysiological parameters of the HRV of animals with different vegetative status
Authors: Naumov M. , Stepura E. , Naumov N. , Burzhinskiy A.
Published: January 2023

Studies of the electrophysiological indicators of the VCR in the Cows of the Jersey breed with different levels of autonomic regulation were not previously carried out, and their normal values in the accessible literature are not described. Given the subtlety of the mechanisms of autonomic heart regulation, there is a need to expand the diagnosis of very common heart disease in animals. The purpose of research is to study the electrophysiological parameters of the variability of the heart rhythm in cattle to assess the possibility of including them in an integrated approach to the analysis of the functioning of the heart in animals. The 103 healthy cows of the Jersey breed studied. The dependence of the change in electrophysiological indicators of the variability of the heart rhythm on the vegetative status of the animal has been studied. To register cardio intervalograms, a computer complex electrophysiological laboratory “Conan - 4.5” was used. The recording was carried out in cattle in a calm state in a standing position. The electrophysiological indicators of the VCR were studied. In this regard, it is advisable to include the assessment of these parameters to include in the basic set of a complex of diagnostics of heart disease in cattle.
Association of SNP localized near DIO2 gene with hormonal profiles of the thyroid axis and fertility indicators in black-and-white cows
Authors: Mityashova O. , Kostyunina O. , Aleinikova O. , Bardukov N. , Lebedeva I.
Published: January 2023

Thyroid hormones can affect the reproductive function of cows through the regulation of various metabolic pathways. The activity of the thyroid system is under the control of three types of deiodinases (DIO). In cattle, there are several genetic variants for the DIO1 and DIO3 genes, but there is no information on the polymorphism of the DIO2 gene.

Purpose: to conduct a search for genetic variants for SNPs in the DIO2 gene and in nearby regions and investigate their association with prepartum and postpartum thyroid profiles and reproductive performance in dairy cows.

Materials and methods. Black-and-white cows of calving 2-4 were used in the experiments. Before calving and after calving, blood was taken from the animals to determine the concentration of hormones by ELISA. The assessment of the luteal activity of the ovaries was performed on the basis of an ultrasound study and the content of progesterone in the blood. Genotyping was performed on 48 samples of cow DNA using a Bovine GGP 150K biochip.

Results. No SNPs present on the Bovine GGP 150K chip were found within the target gene. The SNP Bovine- HD1000026761, localized upstream of the DIO2 gene, was selected for research, with a frequency of genotypes being 45.83% (AA), 47.92% (AG), and 6.25% (GG). In cows with the AA and AG genotypes, a decrease of 1.4 times (p<0.01) in the blood concentration of total thyroxine (T4) 2 weeks before calving, compared with that for 4 weeks, and its further decrease by 1.5 -1.9 times (p<0.001-p<0.05) by the 1st week of lactation were found. From the 6th to the 2nd week before parturition, this indicator was 1.5–1.6 times higher (p<0.001–p<0.05) in individuals with the AG genotype than in ones with the AA genotype. In animals with the AG genotype, a decrease in the blood concentration of reverse T3 (1.4 times, p<0.05) between the 4th week before calving and the 1st week of lactation was revealed. At the same time, this concentration was relatively constant in the animals of the other two groups. Furthermore, in animals with the AG genotype, the content of rT3 in the blood was 1.3 times lower than in animals with the AA genotype from the 3rd to the 7th week of lactation. In cows with a heterozygous genotype, the T4/T3 ratio increased 2.1 times (p<0.001) between the 2nd week before calving and the 1st week after calving, and then decreased 2.2 times (p<0.001) to the 3rd week. After 1 week of lactation, this ratio was 1.9 times higher (p<0.001) than in animals with the AA genotype. Meanwhile, the frequency of occurrence of individuals with the shortest period of recovery of the ovarian function and open days period was the lowest in the group with the AA genotype.

Conclusions. The data obtained indicate that the SNP BovineHD1000026761, located upstream of the DIO2 gene, is associated with long-term changes in thyroid hormone levels in the prepartum and postpartum periods.
Digestibility Quality of Elephant Grass (Pennisetum purpureum) and Concentrate with The Addition of Urea Molasses In Vitro
Authors: Fariani Armina , Pratama Anggriawan Naidilah Tetra , Muslim Gatot , Warly Lili
Published: January 2023

This study aimed to study the digestibility quality of Elephant Grass (Pennisetum purpureum) and concentrate with the addition of urea molasses in vitro. The study was conducted in vitro using an experimental method. The design used was a completely randomized design (CRD) with four treatments and five repetitions: T0 (Elephant Grass 100%), T1 (Elephant Grass 60% + 40% Concentrate), T2 (Elephant Grass 60%) % + Umos 40%) T3 (Elephant Grass 60% + Concentrate 20% + Umos 20%). The results showed no effect (P>0.05) of the combination treatment on dry matter digestibility. Meanwhile, T2 and T3 treatments affected the fermentation quality, including VFA, NH3, total gas production, and methane gas concentration.
Kecernaan Nutrien dan Energi Metabolis Semu Ayam Broiler Yang Disuplementasi Nukleotida Pada Suhu Lingkungan Berbeda
Authors: Rusydy A. F. , Mahfudz L. D. , Nasution Maulana Hamonangan
Published: January 2023

Penelitian ini bertujuan untuk mengkaji pengaruh penambahan nukleotida dalam ransum ayam broiler yang dipelihara pada suhu lingkungan berbeda terhadap kecernaan nutrien dan energi metabolis semu. Penelitian ini menggunakan 135 ekor ayam broiler unsexed berumur 15 hari dengan bobot 462,20±9 gram dan suplemen nukleotida. Rancangan penelitian menggunakan Rancangan Acak Lengkap (RAL) pola faktorial 3×3 dengan 5 ulangan. Perlakuan pertama yaitu level penambahan nukleotida N0 (0 g/kg ransum), N1 (0,5 g/kg ransum), N2 (1 g/kg ransum) dan perlakuan kedua perbedaan suhu lingkungan S1 (panas 32±1°C), S2 (nyaman 23±1°C) dan S3 (alami 24-34°C). Parameter yang diukur yaitu konsumsi nutrien, kecernaan lemak, kecernaan protein dan energi metabolis semu. Data yang diperoleh dianalisis ragam dengan uji F pada taraf 5% dengan uji lanjut Duncan. Hasil penelitian menunjukkan bahwa tidak terdapat interaksi (P>0,05) antara level penambahan nukleotida dengan suhu lingkungan berbeda terhadap konsumsi nutrien, kecernaan lemak, kecernaan protein, konsumsi energi dan energi metabolis semu. Suhu lingkungan panas menurunkan konsumsi lemak, protein dan energi (P?0,05). Penambahan nukleotida 1 g/kg menurunkan (P?0,05) kecernaan protein, konsumsi energi dan energi metabolis semu. Disimpulkan bahwa penambahan nukleotida 1g/kg ransum dapat meningkatkan efisiensi penggunaan protein dan energi pada ayam broiler.
Antropologi Hukum Menegakan Masalah-masalah Hukum
Authors: rasyidi Gema
Published: January 2023

Hukum adalah suatu sistem yang dibuat manusia untuk membatasi tingkah laku manusia agar dapat terkontrol, selain itu hukum juga merupakan aspek terpenting dalam pelaksanaan atas rangkaian kekuasaan kelembagaan. Hukum mempunyai tugas untuk menjamin adanya kepastian hukum dalam masyarakat. Setiap masyarakat berhak mendapatkan pembelaan didepan hukum, sehingga hukum itu memuat peraturan atau ketentuan-ketentuan tertulis maupun tidak tertulis yang mengatur kehidupan masyarakat dan apabila melanggar akan mendapatkan sanksi.
The "Phonology" option of the LingvoDoc platform as a verification method (based on the data of the Sosva dialect of the Mansi language)
Authors: Kosheliuk Natalia
Published: January 2023

The article presents the results of a study of the field material of the Sosva Mansi dialect of the village of Lombovozh. Its phonological analysis was performed using a modern data processing system "LingvoDoc". Comparison of the system of vowel sounds obtained as a result of this analysis with other phonetic systems of the Sosva dialect proposed by linguists of the XX century, allowed us to come to the conclusion that it is necessary to further refine the phonetic system of this Mansi dialect. Thus, in the course of the study, inaccuracies in the interpretation of the field material of the village of Lombovozh were revealed, and a number of unique phonemes (o, ɛ, e, i, ə, u) were found that have uncharacteristic indicators for the generally accepted parameters F1 and F2 of the international phonetic alphabet, based mainly on the data of the analysis of European languages.
PENGGUNAAN MINYAK JAGUNG SEBAGAI BAHAN BAKU BIODIESEL
Authors: Abidin Riskia Rofli
Published: January 2023

Bahan bakar minyak (BBM) merupakan permintaan energi global terbesar yang konsumsinya diperkirakan oleh Energy Information Administration (bagian dari Departemen Energi AS) meningkat sebesar 57% dari tahun 2002 hingga 2025. Ketersediaannya yang terbatas dan kebutuhan masyarakat yang meningkat akan bahan bakar cair jelas merupakan masalah yang mulai signifikan. Salah satu penerapannya adalah pada mesin diesel. Di Indonesia, bahan bakar mesin diesel yang paling banyak digunakan adalah biodiesel dan Pertamina dex yang memiliki sifat berbeda. Beberapa cara telah dilakukan pemerintah untuk menekan laju penggunaan solar dengan menciptakan energi alternatif, salah satunya dengan menggabungkan campuran BBM dengan biodiesel. Minyak nabati merupakan sumber energi potensial yang dapat menggantikan bahan bakar fosil karena sifatnya yang sebanding dengan solar, selain merupakan sumber daya yang dapat diperbaharui dan ketersediaannya cukup banyak. Salah satu upaya pemanfaatan hasil minyak nabati adalah pengembangan biodiesel jagung. Minyak jagung merupakan trigliserida yang tersusun dari gliserol dan asam lemak nabati, sedangkan sisanya merupakan bahan non minyak seperti abu, pewarna atau lilin. Tujuan dari penulisan Tugas Akhir ini adalah sebagai berikut: Memperoleh desain kapal yang sesuai dengan wilayah pelayaran sehingga diperoleh bentuk lambung katamaran yang dapat memenuhi kebutuhan nelayan di perairan Kalimantan Timur. Menganalisis kestabilan yang dihasilkan oleh kapal penangkap ikan dengan tipe lambung katamaran. merupakan bentuk ester dari minyak nabati setelah terjadi perubahan sifat kimia akibat proses transesterifikasi yang memerlukan penambahan metanol. Biodiesel adalah penerapan solusi bahan bakar alternatif untuk menggantikan bahan bakar fosil, yang umumnya berasal dari sumber terbarukan seperti minyak nabati dan lemak hewani. Dibandingkan dengan bahan bakar fosil, bahan bakar biodiesel memiliki keunggulan antara lain dapat terurai secara hayati, tidak beracun, memiliki emisi CO2 dan gas belerang yang rendah serta sangat ramah terhadap lingkungan.Biodiesel / fatty acid methyl ester (FAME) merupakan bioenergi atau bahan bakar alternatif pengganti minyak solar (minyak fosil) yang dibuat dari minyak nabati maupun hewani. Minyak nabati sebagai sumber utama biodiesel dapat dipenuhi oleh berbagai macam jenis tumbuhan tergantung pada sumber daya utama yang banyak terdapat di suatu tempat atau Negara mengompilasi berbagai hasil penelitian di India tentang Bahan Bakar Nabati (BBN) biodiesel dan menemukan 75 spesies tanaman yang dapat menghasilkan biodiesel, 26 jenis di antaranya, termasuk Jathropa curcas (Jarak pagar), yang memenuhi standar kualitas USA, Jerman, dan Eropa.