bluuebunny/crossref_metadata_2025 huggingface dataset:
Native species exploited by marine aquarium trade in Brazil
Authors: Gurjão Lívio Moreira de , Lotufo Tito Monteiro da Cruz
Published: July 2018

Abstract: Brazil has an important role in marine ornamental trade, exploiting native species for both international and domestic market. A few works have previously assessed wild species exploited by the Brazilian marine aquarium industry and most of them focused solely on fish. Hence, the present paper intends to address an information gap regarding the species currently traded in the country, as well as concerning their conservation statuses. Thus, different sources of information were investigated and each species was categorized in accordance with existing lists of threatened species. A wide variety of native species was identified in Brazilian marine aquarium trade, including not only fish but also invertebrates, seaweeds and macrophytes. Some of these species were legally protected, but are still commerced anyway. Such illegal exploitation of native species causes increasing concerns about the sustainability of the activity. Therefore, in order to reduce environmental impacts caused by marine ornamental trade, Brazilian authorities should encourage the implementation of eco-fees, the purchase of eco-labeled aquarium products, the development of sustainable ornamental aquaculture and ecosystem-based management initiatives.
Instâncias intersetoriais de gestão: movimentos para a reorientação da formação na Saúde
Authors: Vendruscolo Carine , Ferraz Fabiane , Prado Marta Lenise do , Kleba Maria Elisabeth , Martini Jussara Gue
Published: July 2018

Este é um estudo de caso, de abordagem qualitativa, cujo objetivo foi compreender como os fóruns gestores – Comitê Gestor Local e Comissão Coordenadora Geral – do Programa Nacional de Reorientação da Formação Profissional em Saúde (Pró-Saúde), desenvolvido em Chapecó, Santa Catarina, contribuíram com a mobilização da integração ensino-serviço no contexto municipal. As informações foram produzidas mediante observação direta de reuniões das instâncias intersetoriais e entrevistas com membros do quadrilátero da formação em Saúde das referidas instâncias, entre 2012-2013. O tratamento destas ancorou-se na proposta operativa para análise de dados qualitativos. Os resultados distinguem a importância do reconhecimento dos papéis de cada segmento. Apesar dos conflitos, os espaços de encontro dos sujeitos intersetoriais são importantes iniciativas de integração ensino-serviço, sobretudo como possibilidade de transformá-los e contribuir para reorientar as práticas e a formação na Saúde.
Kent Meydanlarının Geçmiş ve Günümüz Görüntülerinin Görsel Peyzaj Kalitesinin Saptanması: İstanbul İli Taksim Meydanı Örneği
Authors: ACARLI Belma , KİPER Tuğba
Published: July 2018

Araştırmada, İstanbul
İli için  önemli bir tarihi birikime
sahip  Taksim meydanı ve yakın çevresinin;  geçmiş ve günümüz durumunun görsel peyzaj
kalitesine ilişkin değişimi irdelenmiştir. Bu doğrultuda çalışmada; alana
ilişkin eski ve yeni kent görünümleri açısından görsel peyzaja ilişkin algısal
farklılıklar saptanmıştır. Çalışma kapsamında görsel peyzaj analizi yöntemi
kullanılmıştır. Bu kapsamda Taksim Meydanı ve yakın çevresinde yer alan kentsel
kimlik açısından önem teşkil eden Taksim Meydanı, Taksim Maksemi, İstiklal
Caddesi, Cumhuriyet Caddesi, Gezi Parkı, Atatürk Kültür Merkezi, The Marmara
Oteli'ne ait 7 şer adet fotoğraftan oluşan
geçmiş ve günümüze ilişkin  görüntüler uzman grubu tarafından 5 ana 18 alt
parametre temelinde 5’li Likert ölçeği kullanılarak değerlendirilmiştir. Tanımlayıcı
istatistiki değerlendirmeler sonucunda, en çok ve en az tercih edilen geçmiş ve
günümüz görünümlerine ilişkin mekânsal karakteristikler tespit edilmiştir.
Theoratical calculations of LASO molecule by using DFT/B3LYP and DFT/HSEH1PBE levels
Authors: PİR Hacer
Published: July 2018

L-Arginin
yarı oksalat (LASO) [C6H15N4O2+.C2HO4-] molekülü sentezlendi ve IR ve 1H NMR ve 13C NMR
spektroskopisi P. Vasudevan ve diğerleri tarafından çalışıldı [1]. Bu
çalışmada, LASO molekülünün geometrik yapısını belirlemek için ilk olarak, LASO
molekülünün moleküler geometrik yapısı Gaussian programı ile hesaplandı. LASO
molekülünün teorik harmonik titreşim dalgaları hesaplandı ve hesaplanan bu
veriler deneysel veriler ile karşılaştırıldı. Deneysel veriler ile teorik
veriler uyumlu olarak gözlemlenmiştir. Dahası, LASO molekülü NMR spektrum
çalışmaları ile açıklandı. Son olarak, lineer olmayan optik (NLO) özelliklerin analizi,
sınır moleküler orbitalleri, moleküler yüzeyler ve Mulliken, APT and NBO popülasyonları
incelendi. Tüm teorik hesaplamalar yoğunluk fonksiyonel teori (DFT) ile B3LYP/6-311
++ G (d, p) ve HSEH1PBE/6-311 ++ G (d, p) seviyelerinde hesaplandı.
Optimization of Turning Process By Using Taguchi Method
Authors: Akkuş Harun , YAKA Harun
Published: July 2018

In this study, AISI 1040 steel is machined on CNC lathes. Taguchi
L16 ortogonal array was used as experimental design. Experiments
were carried out with selected the three cutting parameters. These parameters
were determined as feed rate, cutting speed and cutting depth. Turning
operation was carried out in dry conditions with diamond cutting tools. At the
end of experiments, the values of surface roughness (Rz) on samples were found.
Signal/Noise (S/N) rates were found with using the Taguchi method. According to
the results, feed rate had the most significant effect on Rz among three
factors. In ANOVA analysis, respectively feed rate, cutting depth and cutting
speed are effective at 95% confidence level at Rz value. In repetition
experiments carried out for parameters chosen in Taguchi prediction, it was
identified that Taguchi works with nearly 94% accuracy.
PROBLEMS OF ANALYTICAL CONTROL IN PRODUCTION OF RARE AND PRECIOUS METALS
Authors: Karpov Yu. A. , Baranovskaya V. B.
Published: July 2018

The article focuses on one of the important issues in rare and precious metals industry development – analytical control. It reviews the current state, importance, problems and prospects for analytical control development as an integral part of the rare and precious metal production and product quality assurance. Modern analytical control methods are described, namely atomic spectral, mass spectral, X-ray fluorescent and combined ones as well as their rational applications. It is shown that scientific and technological progress is inextricably linked with a drastic increase in the nomenclature of materials based on rare and precious metals and higher requirements for their quality. This will require creating new and improving existing analytical control methods, their standardization and metrological support. This work should involve research organizations in theRussianAcademy of Sciences, universities, industry research centers with research laboratories that have survived in the country after theSoviet Union dissolution, as well as promote plant research activities. It is necessary to effectively use the achievements of advanced analytical laboratories abroad, participate in international comparative tests. At the same time, special attention is paid to unsolved problems – scientifically justified statement of requirements for new types of products based on rare and precious metals; development and metrological assessment of sampling methods; development of high-quality metrological support for analytical control of rare and precious metal production; improvement of analytical methods; standardization of analytical methods; accreditation of analytical laboratories; training of highly qualified analytical chemists.
FROM METALLURGY OF GRANULES TO ADDITIVE TECHNOLOGIES
Authors: Timofeev A. N. , Logacheva A. I.
Published: July 2018

OJSC «Kompozit» traces its history back to the Central Research Institute of Materials Science (CRIMS) and successfully acts as a leading material science institute in the rocket and space industry up to the present day. The enterprise uses and improves state-of-theart technologies, and creates a variety of new metal, non-metallic, composite and ceramic materials. This article provides an overview of powder sector development from the metallurgy of granules to additive technologies and shows the participation of MISIS graduates. The experience of OJSC «Kompozit» in the manufacturing of parts by selective electron beam melting (SEBM) of home-made VT6S titanium alloy powders. Initial powders are obtained by plasma centrifugal spraying of the bar stock. It is shown that the powders feature an ideal spherical shape, low defect rate, high processability and fully meet the process requirements. The microstructure and properties of samples and parts obtained by the SEBM are studied.
USING MECHANOCHEMICAL TREATMENT TO OBTAIN METAL POWDERS FOR ENERGY-INTENSIVE COMBUSTIBLE COMPOSITIONS: 1. FEATURES OF THE STRUCTURE AND STATE OF ALUMINUM POWDER PARTICLES OBTAINED AS A RESULT OF MECHANOCHEMICAL TREATMENT
Authors: Mofa N. N. , Sadykov B. S. , Bakkara A. E. , Mansurov Z. A.
Published: July 2018

The paper presents the results of mechanochemical treatment of aluminum powder particles in a ball mill using various organic modifiers (graphite, stearic acid, polyvinyl alcohol) as a surfactant additive in order to increase powder dispersity and modify the surface layer of initial particles. Scanning force microscopy, X-ray diffraction analysis, IR spectroscopy and EDX methods were used to study the morphology, dispersion, structure, and the average particle size of aluminum powders after mechanochemical treatment, and this study showed significant changes in the surface layer of particles. It is found that mechanochemical treatment of aluminum with organic additives leads to partial recovery of the oxide surface layer with several types of active centers formed capable of chemical reactions using the resulting compositions in various combustible mixtures. The study showed that with an increase in the content of modifiers, i.e. graphite and polyvinyl alcohol, the activity of aluminum rises in the composite with these additives. When the content of stearic acid in the Al composite increases, the activity index decreases. This may be due to the fact that Аl–C17H35COOH mixture milling with a large amount of stearic acid (more than 5 %) forms a dense capsule layer on the surface of aluminum particles that is poorly soluble in alkali. During mechanical action the composition powders under study show both the accumulation and redistribution of defects throughout the particle, an increase in the active aluminum content, generation of active centers, and formation of an encapsulating layer based on organic modifiers on the aluminum surface.
MECHANICAL ALLOYING WITH PARTIAL AMORPHIZATION OF FE–CR–CO–NI–MN MULTICOMPONENT POWDER MIXTURE AND ITS SPARK PLASMA SINTERING FOR COMPACT HIGH-ENTROPY MATERIAL PRODUCTION
Authors: Kochetov N. A. , Rogachev A. S. , Shchukin A. S. , Vadchenko S. G. , Kovalev I. D.
Published: July 2018

This paper presents the results of studying the mechanical alloying (MA) effect on the surface morphology, microstructure and atomic-crystal structure of multicomponent Fe–Cr–Co–Ni–Mn powder mixture particles. The following materials were used as initial components: radio-engineering carbonyl iron powder (R-10 with an average particle size d = 3,5 μm), nickel powder (NPE-1, d = 150 μm), cobalt powder (PK-1u, d <71 μm), chromium powder (PH-1М, d <125 μm) and manganese powder (MR0, d <400 μm) were used. MA of the prepared mixture was carried out in the AGO-2 water-cooled mechanical activator using 9 mm steel balls with an acceleration of 90 g in air. Alloying time varied between 5 and 90 minutes. The ratio of ball mass to the mass of the mixture was 20 : 1. X-ray patterns of the initial and alloyed mixtures and the sample obtained by sintering were made on the DRON 3M diffractometer on FeKα radiation in the range of angles 2θ = 30°÷100°. The particle microstructure of the mixtures and compact sample section after sintering was studied by scanning electron microscopy. It is found that no peaks of the initial components are present on the X-ray pattern of the mixture after 90 minutes of mechanical activation, but there are peaks corresponding to the γ-Fe-based solid solution phase having a face-centered crystal lattice with an amorphous phase content increased by 20 %. A compact single-phase material was obtained by spark plasma sintering at 800 °С for 10 minutes from the mixture after 90-minute alloying. Material density was 7,49 kg/cm3, specific electrical resistivity was 0,94÷0,96·10–6 ·m, microhardness was 306÷328 kg/mm2, and the phase was distributed uniformly throughout the volume.
DETERMINATION OF PARAMETERS FOR THE PLASTICITY MODEL OF VT-22 ALLOY POWDER PARTICLES
Authors: Kryuchkov D. I. , Zalazinskii A. G. , Romanova O. V. , Nesterenko A. V. , Smirnova E. O.
Published: July 2018

A computational and experimental method is proposed to determine the medium model for describing the mechanical properties of powder particles of a high-strength VT-22 titanium alloy obtained by plasma spraying in an inert gas jet. The method is based on the indirect determination of the σs ~ ε strain hardening diagram (yield stress dependence on plastic deformation). A specimen for fullscale tests was prepared as a section of powder particles filled into a special resin. The paper provides the results of Vickers indentation into VT-22 powder particles and the results of computer simulation of this process by the finite element method. The average value of the maximum indentation depth was hmax = 6,56 μm with a maximum loading value of 2 N. The Johnson-Cook elasto-plastic model of a material with nonlinear hardening was used for the volume element considered during the computer simulation. An algorithm for searching coefficients by computational experiment multistage planning was proposed to identify the parameters of the equation sought. Estimated maximum coincidences of experimental and calculated data were chosen as selection criteria, in particular, based on maximum indentation depth. As a result of the study, material model coefficient values that meet search conditions best were chosen from a possible set of such values. According to the algorithm proposed, the result was achieved in 4 calculation cycles. Powder metallographic study was carried out. It was found that particles have a coarse intragranular structure with the dominating b phase formed during plasma spraying. This probably led to a decrease in VT-22 alloy deformation resistance in the powder particles.
SYNTHESIS OF COMPOSITE POWDERS «TIC – NICRBSI ALLOY BINDER» FOR CLADDING AND DEPOSITION OF WEAR-RESISTANT COATINGS
Authors: Pribytkov G. A. , Firsina I. A. , Korzhova V. V. , Krinitсyn M. G. , Polyanskaya A. A.
Published: July 2018

TiC + NiCrBSi binder metal matrix composites were obtained by self-propagating high-temperature synthesis (SHS) in the reaction powder mixtures of titanium, carbon (carbon black) and NiCrBSi alloy. It has been found that steady combustion in a stationary mode occurs when the content of the thermally inert metal binder in reactive mixtures does not exceed 50 vol.%. Porous SHS cakes were crashed and resulting granules were separated to fractions by screening to get the composite powder fraction necessary for coating application. Synthesis products were studied by optical and scanning electron microscopy, X-ray diffraction and electron microprobe analysis. It has been found that the average size of carbide inclusions depends on the content of thermally inert alloy powder in the reaction mixtures and can be purposefully regulated in a wide range. The microhardness of composite powder granules obtained by crushing the SHS conglomerates decreases monotonically with an increasing content of the metal binder having hardness less than that of titanium carbide. According to X-ray diffraction data, the titanium carbide lattice parameter turns out to be considerably less than values known for equiatomic titanium carbide. It has been found by electron microprobe analysis of carbide inclusions in the composite structure that the ratio of carbon and titanium mass contents is 0,21 as compared with 0,25 in equiatomic titanium carbide. Iron and silicon contents in the carbide are negligible, oxygen and nickel contents are below 1 wt.%, and chromium content is 2,5 wt.%. The analysis of known data on the effect of all the above-listed dopants on the titanium carbide lattice allows for a conclusion that the carbon deficit is a main reason of the lattice parameter reduction.
2×CTAB Protocol for Isolation of predominantly Symbiodinium DNA from symbiotic anemones v1
Authors: Lab Pringle , CR Renicke Christian
Published: July 2018

This protocol is kit-free and can be used to isolate high quality genomic DNA of predominantlySymbiodiniumfrom symbiotic Aiptasia which can be used as e.g. PCR template for genotyping. It is based on the method described in Coffroth et al., 1992.
DNA Extraction from Symbiodinium Cultures v1
Authors: Xiang Tingting , Grossman Arthur
Published: July 2018

Dinoflagellates are unicellular algae that can have photosynthetic or nonphotosynthetic lifestyles. Dinoflagellates in the genus Symbiodinium can enter endosymbiotic associations with corals, providing the metabolic basis for the highly productive and biologically diverse coral-reef ecosystems (Hoegh-Guldberg, 1999), as well as with other cnidarians, including sea anemones and jellyfish, and noncnidarian hosts (Trench, 1993; Lobban et al., 2002; Mordret et al., 2016). Here I describe a protocol for isolating totalDNA from Symbiodinium cells.
2×CTAB Protocol for predominantly host DNA isolation from symbiotic Aiptasia v1
Authors: Lab Pringle , CR Renicke Christian
Published: July 2018

This protocol is kit-free and can be used to isolate high quality genomic DNA ofpredominantly Aiptasia fromsymbiotic anemones which can be used e.g. as PCR template for genotyping. It is based on the method described in Coffroth et al., 1992.
Using genomic SCAR markers for genotyping Aiptasia strains v1
Authors: Lab Pringle , CR Renicke Christian
Published: July 2018

This protocol describes (1) how to amplify the genomicmarkers SCAR3, SCAR4, SCAR5 and SCAR7 (developed by Thornhill et al., 2013) from genomic DNA of Aiptasia,(2) how to use Gibson Assembly® to clone them into a (pCR™II-TOPO®-derived) plasmid and (3) performing colony PCRs to screen for clones to sequence by Sanger sequencing. The subcloning is highly recommended since strainsmight be heterozygous for some or all of the markers. SCAR:Aiptasia-specific inter-simple sequence repeat (ISSR)-derived sequence characterized amplified region markers. Legal disclaimer: GIBSON ASSEMBLY®is a registered trademark of Synthetic Genomics, Inc. pCR™ and TOPO® aretrademarks of Thermo Fisher Scientific and its subsidiaries. GoTaq® is a registered trademark of Promega Corporation.
Colonization of aposymbiotic Aiptasia with Symbiodinium v1
Authors: Lab Grossman , Lab Pringle
Published: July 2018

This protocol describes briefly how to perform colonization of aposymbiotic Aiptasia with Symbiodinium cultures. The method isbased on the one described in Xiang et al., 2013.
Preparing small, live Aiptasia polyps for confocal microscopy v1
Authors: Weis Lab OSU , Tivey Trevor
Published: July 2018

This protocol, which was developed in 2006 bySantiago Perez while in the Weis lab, provides a way to temporarily immobilize small Aiptasia for live imaging on a confocal microscope. As written, the protocol is used for inverted confocal microscopes, but the glass-bottom dishes can be replaced with a normal glass slide and coverslip for an upright microscope.
A high throughput, cost-efficient library preparation protocol for large scale next generation sequencing v2
Authors: Zan Yanjun , Carlborg Örjan
Published: July 2018

Previously, Picelli et al (Picelli et al., 2014) reported a Tn5 transposase-based library construction procedure for Illumina sequencing. Here, we describe an optimised procedure for high throughput library preparation to facilitate large-scale sequencing that does not rely on advanced lab equipment. The Tn-5 transposase used can be purified using a publicly available construct (Picelli et al., 2014). Reaction buffers and primers can be prepared using standard chemicals available from common suppliers.
RNA extraction, reverse transcription and PCR for TMSB4X v1
Authors: Saunders Vinay , I Wilson David
Published: July 2018

Procotol describing RNA extraction from dissected human tissue followed by reverse transcription to cDNA, PCR for detection of TMSB4X and separation of PCR products by agarose gel.
Fluoresence immunohistochemistry v1
Authors: Saunders Vinay , I Wilson David
Published: July 2018

Protocol describing fluorescence immunohistochemistry for PFA-fixed mammalian tissue samples.
Giant Unilamellar Vesicles (GUVs) Preparation by Electroformation Method v1
Authors: Kahveci Zehra
Published: July 2018

Preparation of giant unilamellar vesicels (GUVs) by electroformation method has been detailed. 10 to 100 micrometer size GUVs obtained after the process.
Peculiarities of roentgenological picture of pulmonary tuberculosis upon HLA-DRB1 gene polymorphism depending on pro-and-antiinflammatory cytokines concentration
Authors: Stepanova N. A. , Kantemirova B. I. , Galimzyanov Kh. M.
Published: July 2018

Aim. To study the peculiar features of roentgenological picture of pulmonary tuberculosis in patients with polymorphous HLA-DRB1 allels in the genotype in associations with pro-and-antiinflammatory cytokines concentration.

Materials and methods. The complex clinicoimmunogenetic examination of 64 patients with pulmonary tuberculosis was carried out. The patients’ age ranged 18 to 52 years. The gene HLA-DRB1 polymorphism was determined using the method of polymerase chain reaction with DNA, previously extracted from blood samples. Cytokine concentration was determined in the peripheral blood before specific treatment, using the assay kits of “Vector-BEST Company” (Russia).

Results. The prevailing clinical form of pulmonary tuberculosis among patients was infiltrative one – 40 (62.5). Bacterioexcretion was stated in 89.5 % of cases. Roentgenological picture of pulmonary tuberculosis in patients with HLA-DRB1 *04, *13, *14, *16 alleles was characterized as disseminated injury of lung tissue with destructive changes, the concentration of IL-1b, TNF-α exceeded the standard values by more than 3 times (r = 0.88; р = 0.040), IL-2, IL-10, g-INF was lower than standard values by more than 4–5 times (r = 0.75; р = 0.003).

Conclusions. When studying HLA-DRB1 gene polymorphism and pro-and-antiinflammatory cytokines concentrations in patients with pulmonary tuberculosis, it was established that patients with HLA-DRB1 *01, *07, *08, *10, *15 alleles more often, compared to the others, had disseminated injury of lung tissue, in most cases with its destruction as well as dysbalanced cytokine balance in the direction of deep immunosuppression.
Peculiar features of immunogenetic parameters in children with atopic diseases
Authors: Illek Ya. Yu. , Vyaznikova M. L. , Leushina N. P. , Mischenko I. Yu. , Ryseva L. L. , Solovieva G. V. , Tarasova E. Yu.
Published: July 2018

Aim. To determine the peculiarities of distributing antigens of major histocompatibility complex in children with atopic dermatitis and children with bronchial asthma.

Materials and methods. Serologic typing of HLA class I-complex antigens and molecular typing of HLA class II-complex antigens was fulfilled in 52 children (age range 5 to 14 years) with disseminated moderate and severe atopic dermatitis and 122 children (age range 5 to 14 years) with moderate and severe atopic bronchial asthma.

Results. Among children with atopic dermatitis, there was found high incidence rate of HLA-complex antigens B15, B16, B17, DRB1*13 and DQB1*0602-8, presentation of which was associated with elevation of relative risk for the development of disease by 3.3–8.4 times. In children with atopic bronchial asthma, the observed high incidence rate of HLA-complex antigens A26, B18 and DRB1*17 was associated with rise of relative risk for the development of disease by 3.0–9.1 times.
Hygienic assessment of foreign students’ living conditions in the hostel of perm state medical university
Authors: Koryukina I. P. , Kulesh T. A. , Zueva T. V. , Arbuzova T. P.
Published: July 2018

Aim. To present the hygienic assessment of foreign students’ living conditions in the hostel of Perm State Medical University.

Materials and methods. Sanitary-epidemiological estimation of arrangement, equipment and maintenance of the hostel for Indian students was performed. Hygienic assessment of the hostel territory, rooms and accommodations for common use, equipment and facilities of the building and rooms was presented. In the living and auxiliary rooms, sanitary-hygienic tests (measurements) regarding microclimate (90), infrared radiation (20), noise level (45), electromagnetic radiation (40), natural and artificial light (65) were fulfilled.

Results. Objective assessment of social factor and living conditions, influencing adaptation of foreign students to new climatico-geographic conditions was obtained. The living conditions for foreign students in the hostel of Perm State Medical University correspond to sanitary-epidemiological rules and standards, except for the level of noise.

Conclusions. Favorable social and living conditions, offered to Indian students in the student’s hostel, help them to overcome difficulties, connected with adaptation of foreign medical students.
BİLGİ PAYLAŞIMINI ETKİLEYEN FAKTÖRLER VE BİLGİ PAYLAŞIM SÜRECİNİN YENİLİKÇİ İŞ DAVRANIŞINA ETKİSİ
Authors: IŞIK Metin
Published: July 2018

Bu araştırmada bilgi paylaşımını etkileyen faktörler ve bilgi paylaşım sürecinin yenilikçi iş davranışına etkisi ortaya konmaya çalışılmıştır. Araştırma, Bitlis ilinde faaliyet gösteren kamu ve özel bankalardaki çalışanlar üzerinde yapılmıştır. Araştırmaya veri toplamak amacıyla yapılandırılmış soru formu yöntemi kullanılmış olup, örneklem seçiminde basit tesadüfi örneklem metodu benimsenmiştir. Elde edilen veriler araştırmanın hipotezlerini test etmek amacıyla SPSS programında korelasyon ve çoklu regresyon analizlerine tabi tutulmuştur. Analiz sonuçlarında; bilgi paylaşımını etkileyen faktörler, bilgi paylaşım süreçleri ve yenilikçi iş davranışı arasında yüksek düzeyde pozitif yönlü anlamlı ilişkiler tespit edilmiştir. Bilgi paylaşımını etkileyen bireysel faktörlerden; yardımseverlik, örgütsel faktörlerden; üst yönetim desteği ile örgütsel ödüllerin bilgi paylaşım sürecini etkilediği, diğer taraftan bireysel faktörlerden; bilgi öz yeterliliği ile teknolojik faktörlerden; bilişim teknolojileri kullanımının bilgi paylaşım süreci üzerinde herhangi bir etkisinin olmadığı görülmüştür. Son olarak, bilgi paylaşım sürecinin bilgi toplama boyutunun yenilikçi iş davranışı üzerinde önemli bir etkiye sahip olduğu, ancak bilgi paylaşma boyutunun yenilikçi davranışı üzerinde bir etkisinin olmadığı sonucu bulgulanmıştır.
UİK e-SPOR ENDÜSTRİSİ
Authors: YÜKÇÜ Süleyman , KAPLANOĞLU Emre
Published: July 2018

Ülkemizde
30 milyondan fazla kişi farklı dijital platformlar üzerinden dijital oyunlar
oynamaktadır. Yerel oyun endüstrisinin büyüklüğü yıllık yaklaşık olarak 700
milyon dolardır. Dijital oyun endüstrisi yıllık ortalama olarak %16 ila %18
arasında büyümektedir. Rekabete dayalı bilgisayar oyunlarının hem oynanması hem
de izlenmesinin elektronik spor (e-Spor) kavramının doğmasına neden olduğu
söylenebilir. Dünya’da en az 385 milyon kişi e-Spor seyircisi, 100 milyondan
fazla kişi e-Spor oyuncusu ve Türkiye’de en az 7 milyon oyuncu e-Spor
ekosisteminde oyuncu ve izleyici olarak yer almaktadır. e-Sporun 2017 yılında
dünya genelinde elde ettiği gelir 696 milyon dolara ulaşmıştır. Bu çalışmanın
amacı henüz emekleme aşamasında olan e-Spor endüstrisinin tarihini, ticari
modellerini, e-Spor oyun türlerini, paydaşlarını, mevcut ve gelecek ekonomik
durumunu ortaya koymak ve bu alanda yapılacak çalışmalar için öneriler
getirmektir.
STRATEJİK MALİYET YÖNETİMİ- BİST’E KOTE İMALAT İŞLETMESİ ÜZERİNE ARAŞTIRMA
Authors: TÜNEL Rabia Kübra , GÜLENÇER İlker
Published: July 2018

Küreselleşmenin,
geliştirilen yeni teknolojilerin, artan müşteri ihtiyaçlarının, rekabetin ve
hızlı bir değişimin olduğu günümüzün iş dünyasında işletmelerin başarıya ulaşma
olanakları oldukça zor hale gelmiştir. 
Dünyadaki değişimlerden çok hızlı etkilenen sanayi işletmelerinde de
başarıya erişme fırsatı giderek azalmaktadır. Günümüz ortamında sanayi
sektöründe yaşanılan rekabet giderek hızlanmaktadır. İmalat sektörü; sağladığı
istihdam olanakları, tedarikçi işletmelere olan katkısı ve başka sektörlere
kattığı değer nedeni ile ülke ekonomisinde çok önemli yere sahiptir. Günümüz
ekonomisinde, pazar olanaklarından yararlanabilmek ve rekabet koşullarına uyum
sağlayabilmek adına maliyetlerin daha iyi yönetilmesi büyük önem arz
etmektedir. Bu çalışmanın amacı, artan rekabet ve müşteri isteklerinin daha
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Clinical profile of HIV positive patients attending ART centre of a tertiary care hospital
Authors: Doshi Tejas M. , Mistry Rusva A. , Mehta Manish N.
Published: July 2018

Background: HIV infection/AIDS is a global pandemic greatly exceeds earlier prediction. With widespread availability and uses of Anti Retroviral Therapy (ART), HIV becomes a chronic manageable illness but immediate and long term side effects become a major problem. The objective of the study was to study clinical profile of HIV positive patients attending A.R.T. centre of a tertiary care hospital.Methods: Observational and prospective study was carried out over 100 HIV positive Patients attending ART centre of G.G.G Hospital, Jamnagar, Saurastra, Gujarat over a period of 12 months.Results: Out of 100 HIV positive studied patients, maximum cases (95%) were in the age group of 15-49 years, 75% were males. (58%) cases were from rural area and (56%) were illiterate. Maximum cases were having sexual (79%) route of transmission. Most common symptom among HIV positive patients was weight loss (62%) followed by fever (58%). Mycobacterium tuberculosis (65%) was the most common opportunistic infection. (84%) patients had CD4 count between 50-200/cub.mm, (66%) were in stage III. ART was well tolerated, ADRs were found in 43% of patients.Conclusions: HIV is more common in reproductive age group with males being more affected and major route of transmission of HIV infection remains heterosexual mode.
Analysis of spontaneously reported adverse drug reactions to pharmacovigilance cell of a tertiary care hospital
Authors: Patel Kaksha J. , Panchasara Ashwin K. , Barvaliya Manish J. , Tripathi C. B.
Published: July 2018

Background: The objective of the study was to study the clinical patterns, causality and severity of adverse drug reactions in a tertiary care hospital.Methods: Total 131 ADR forms were collected from January 2012 to December 2012 and evaluated. Patient’s characteristics, ADR and drug characteristics, causality, severity and preventability of collected ADR were analyzed.Results: Total 131 ADR forms were evaluated. Male patient experiencing ADR were more (73, 55.7%) than female (58, 44.2%). Adult patients (12-60 years) experienced 110 (84%) ADR followed by pediatric patients (< 12 years) 11 (8.4%) and geriatric patients (>60 years) 10 (7.63%). Antimicrobial were the most common group of drugs responsible for ADR followed by NSAIDs and antipsychotic group.Conclusions: Present study shows lack of awareness among health care professionals for reporting of an ADR. Training and collaboration of health care professionals are needed for improvement in ADR reporting. Appropriate feedback from ADR reporting will help in selection of drug and promotes safer use of drugs.
A comparative study to assess the awareness of antibiotic resistance amongst first and second year medical undergraduate students in a medical college
Authors: V. D. Bharath Kumar , L. Kalpana
Published: July 2018

Background: With the rising instances of antibiotic resistance and decline in the discovery of newer antibiotics, it is high time to prevent the emergence of antibiotic resistance. One of the best measures regarding the above problem is education and creating awareness regarding antibiotic resistance, and that too primarily among healthcare professionals. The initiation should start at the basic level and that too in the early days of medical profession, so that there is greater awareness and strong foundation for antibiotic prescribing pattern. The present study is taken up to compare awareness among 1st year and 2nd year medical students in a private medical college with 2nd year medical students having prior education regarding antibiotics resistance and first year students representing general public without any education regarding antibiotics resistance.Methods: This study was a comparative, cross-sectional, questionnaire based study. The questionnaire was validated for face validity and content validity from subject experts. The two groups selected were 1st year and 2nd year medical undergraduates. Data was analysed using simple descriptive statistics.Results: 136 students from 1st year and 88 students from 2nd year participated in the study. In both the groups studied, majority of the respondents completed the full course of antibiotics. 77% of 1st year and all 2nd year students were aware of the antibiotic resistance. 99% of 2nd year students and only 49% of the 1st year students were aware of the reasons for it (p<0.01). Awareness regarding prophylactic usage of antibiotics, usage for simple common cold and usage of higher antibiotics for mid infection leading to Antibiotic Resistance was significantly less among first year students. 2nd year students were well aware of consequences of antibiotic resistance like ineffective treatment, prolongation of illness, emergence of bacterial resistance and additional cost burden than 1st year students. Awareness regarding other aspects of antibiotic resistance was not significant between two groups.Conclusions: Stressing upon awareness and education regarding antibiotic resistance in the early days of medical curriculum will help in change of behaviour and habits of antibiotic usage and rational prescribing of antibiotics by the future doctors.
A questionnaire based survey on the knowledge, attitude and practices about antimicrobial resistance and usage among the MBBS students and doctors of a tertiary care teaching Hospital in Silchar, Assam, India
Authors: Yashin Ali N. , Thakuria Nishanta , Narzary Hiranmoy , Satnami Dinesh , Paul Nilanjan
Published: July 2018

Background: Antimicrobials are agents used to kill or inhibit growth of microorganisms. Now they are most commonly used as well as misused medicine too. Misuse of these agents lead to development of resistance which is now a global concern. Public awareness about antimicrobial resistance is a key factor in combating the situation which includes educating doctors and health care professionals. So the current study is undertaken to assess the knowledge, attitude and practices (KAP) related to antibiotic resistance and usage and among the MBBS students and doctors.Methods: A pre-formed duly validated questionnaire was distributed among the study group and their KAP regarding antimicrobial usage and resistance was assessed by Likert scale whose responses ranges from strongly agree to strongly disagree and always to never. Some questions were of true/false type. One question was choosing the correct answer. In this study, questionnaires were distributed among 270 participants out of which 188 were MBBS students and 82 were doctors. After collection, data were entered in Microsoft excel and simple descriptive statistics were used to generate frequencies, percentage and proportions. Wherever possible the chi-square test or fisher exact test was done to find out any association. * p<0.05 was taken as significant.Results: Response rate was 100% among the study populations. Out of 270 study population, 91% (245) had the knowledge that indiscriminate use of antibiotics cause ineffective treatment with a considerable difference in knowledge between undergraduates and doctors (p<0.05). Also it causes bacterial resistance (96.3%). Around 89% of the total participants agreed that bacteria do not cause common cold and influenza.Conclusions: This study revealed that most of the study population, both undergraduates and doctors were well aware about the emerging problem of antimicrobial resistance. However, responses related to their practices were quite varied. Hence, further educational interventions are needed to improve their practices towards antibiotics use in both the study groups.
Self medication among medical and dental students in tertiary care teaching hospital of Udaipur, India
Authors: Chawda Hiren M. , Panchasara Ashwinkumar K.
Published: July 2018

Background: Self‐medication involves acquiring and consuming medication without the advice of a physician and also resubmitting old prescriptions to purchase medicines. Inappropriate self‐medication causes increase cost of therapy and incidence of adverse drug reactions. Self-medication was significantly higher among undergraduate medical and paramedical students in India. Objective of the study was to evaluate the prevalence of self-medication and perception towards self-medication among the undergraduate medical and dental students.Methods: A pre-designed questionnaire collected the information pertaining to demographic details like age, gender, course, reason, pattern, indications, drugs used for self‐medication. It also included questions concerning their attitude, perception and safety regarding self-medication.Results: The prevalence of self - medication was 76.27%. Larger numbers of females were self-medicating (55.56%). The majority of the students’ self-medicated because of other advice (92.59%), there was statistically significant difference between the male and female medical students to use a previous prescription for the same illness. A total of 136 (76.83%) of the participants opined that self-medication was a part of self-care. Statistically significant differences between male and female students had been observed in safety variables like, “know side effects about your drug”, “increasing drug dose can be dangerous” and “in case of side effects physicians’ help must be sought”. Cold and Cough was the most common (60%) indication for self-medication.Conclusions: The prevalence of self-medication was higher among females. The majority of the students’ self-medicated because of other advice. The stringent policies should be required for medicines which can prevent the increasing trend of self-medicating.
A case series of cefixime induced Steven’s Johnson Syndrome
Authors: Rao Arikeri Vasu Deva , Khan Imran , Velupula Srinivas , N. Jayababu , L. Samarasimha Reddy , M. Kiran Kumar
Published: July 2018

Drug induced adverse reactions are a major health problem. Drug hyper sensitivity reactions manifest themselves in many diseases, of which some are very severe. The most common allergic reactions occur in the skin. Stevens-Johnson syndrome is mainly caused by drugs (antimicrobials e.g.: penicillin’s, sulphonamides and cephalosporin’s e.g.: cefixime, antiepileptic’s, NSAIDS), infections and also by other risk factors not yet identified. The most common allergic reactions occur in the skin. These reactions ranging from simple pruritic eruptions to potentially life threatening events are a significant cause of iatrogenic morbidity and mortality. Identification of the cause, withdrawal of the trigger and supportive management is crucial to improve the patient state. Despite of all therapeutic efforts, mortality is high and increases with disease severity, patient’s age and underlying medical conditions. Survivors may suffer from long-term squeal such as strictures of mucous membranes including severe eye problems.
Angioedema caused by over the counter use of dicyclomine hydrochloride and paracetamol fixed dose combination in a child: a case report
Authors: Raghute Latesh B. , Dudhgaonkar Sujata , Jaiswal Kavita M. , Parihar Akhilesh Singh , Bhalerao Swapna M. , Jumle Sagrika R.
Published: July 2018

Authors describe a case of angioedema in a male child due to over-the-counter (OTC) use of fixed dose combination (FDC) of Tab. dicyclomine hydrochloride (20mg) and paracetamol (500mg) for abdominal pain. Use of OTC drugs in children without a doctor’s suggestion can lead to unnecessary medication use and is not free of risks. Here, there is a probable causal relationship between the suspected drug and angioedema according to WHO-UMC criteria for Causality Assessment. This case was also reported to the Pharmacovigilance Programme of India (PvPI) through PvPI ADR android application.
Pattern of internet addiction among urban and rural school students, Mangaluru, India: a comparative cross-sectional study
Authors: A. Sowndarya T. , Pattar Mounesh
Published: July 2018

Background: Adolescents use the Internet for a variety of activities besides gaming; they frequently engage themselves with social networking, instant messaging, blogging and downloading information. Heavy Internet use has been associated with potential side effects, such as loss of control over the use of the Internet, adverse effects on other daily activities, emotional status and communication among family members. Objective of present study to assess the prevalence of Internet Addiction (IA) and factors associated with Internet use among Urban and Rural school students.Methods: A school based cross sectional study was conducted in the urban and rural field practice area of a medical college hospital in Mangaluru. Internet addiction was assessed using Young’s Internet Addiction Test.Results: The prevalence of internet addiction among urban school students was found to be i.e. 83.3%, while it was 78% in rural school students. Mild IA was common among both.  Male gender, smart phones and hours spent on internet were common risk factor for IA in both groups.Conclusions: Young’s Internet Addiction Test (IAT) is a simple and easy tool to assess Internet addiction among adolescent school students. Need to give importance of outdoor activity and community level education needed to prevent Internet Addiction.
Normal range of white blood cells and differential count of Sudanese in Khartoum state
Authors: Taha Elmutaz H. , Elshiekh Mohammed , Alborai Abdelrahim , Hajo Elnagi Y. , Hussein Abdelmohisen , Awad Kamal M. , Ali Ibrahim A. , Musa Omer A.
Published: July 2018

Background: The normal physiological range for white blood cells and differential count are essential for diagnosis, treatment, follow up and screening. This study aimed at establishing the reference ranges of WBCs and differential count in Sudanese people.Methods: The present study included 444 healthy adult Sudanese from both sexes with age range of 20 – 60 years. Blood samples were obtained from brachial veins and drawn in EDTA tubes. WBCs and differential count were analyzed using Sysmex KX-21 automated hematology analyzer. Full clinical examination was performed, weight and height were measured, and BMI was calculated.Results: The mean WBC count was 5.1±1.5×103/ µl with a range of 3.6 ×103/µl to 6.6 ×103/µl. The mean WBCs count for males and females were 4.969×103/µl and 5.138×103/µl respectively. Neutrophils count was 2.430×103/µl (47%) and mean for lymphocyte count was 2.116×103/µl (41.1%).Conclusions: WBCs count was directly proportional to BMI. The WBCs count of Sudanese people was lower than that of Caucasians and similar to reports from other African countries.
Biofilm production and its correlation with antibiotic resistance pattern among clinical isolates of Pseudomonas aeruginosa in a tertiary care hospital in north-east India
Authors: Saha Swarnatrisha , Devi Ksh Mamta , Damrolien Shan , Devi Kh. Sulochana , . Krossnunpuii , Sharma Kongbrailatpam Tharbendra
Published: July 2018

Background: Pseudomonas aeruginosa is an ubiquitous pathogen capable of surviving in a variety of environmental conditions. It is increasingly gaining importance as a multidrug resistant nosocomial pathogen. Biofilm acts as a barrier, reducing the penetration of these drugs and consequently, preventing them from exercising their actions. The aim of this study is to isolate and identify Pseudomonas aeruginosa from various clinical specimen and to find out their production of biofilms and their correlation with antibiotic susceptibility pattern.Methods: All Pseudomonas aeruginosa over a period of 1 year were isolated and identified from clinical specimens and antibiotic susceptibility test was done following standard operative procedures. Biofilm detection was done by Congo Red Agar method (CRA).Results: 134 isolates of Pseudomonas aeruginosa was isolated. Maximum isolates were isolated from sputum samples 55 (41%) and most were from wards 68 (51%) giving a probability of increased healthcare associated infections. Biofilm production by the isolates was seen in 39 (29%). All the biofilm producing isolates shows more resistant pattern in comparison to non-biofilm producers. 69% of Imipenem and 82% of Meropenem resistant isolates produce biofilm. All the P. aeruginosa including MDR and biofilm forming strains were sensitive to Colistin.Conclusions: Resistance to antimicrobial agents is the most important feature of biofilm infections. Ability of P. aeruginosa to form biofilms renders antibiotic treatments inefficient and therefore promotes chronic infectious diseases.  As a result, infections caused by bacterial biofilms are persistent and very difficult to eradicate.
Prevalence and risk factors of acid peptic ulcer disease at a tertiary care hospital
Authors: Chavan Manohar Shankarrao , Bhaktavatsalam M.
Published: July 2018

Background: In day to day practice, at outpatient department of General Medicine, at Mahavir Institute of Medical Sciences, Vikarabad, Telangana, India authors are coming across a significant number of patients with acid peptic disease (APD). This prompted us to carry out the present study. The objective is to study the prevalence, risk factors of acid peptic disease and to give suitable recommendationsMethods: Present study was hospital based cross sectional study carried out at outpatient department of General Medicine for a period of ten months from June 2017 to March 2018 among 307 outpatients.Results: The prevalence of acid peptic disease was found to be very high in the present study i.e. 38.1%. This was very high compared to the available literature. The prevalence of acid peptic disease was significantly associated with increasing age, lower social class, alcohol use, tea use and NSAID use. Acid peptic disease was not found to be associated with sex, residence, literacy, smoking, coffee intake, and obesity.Conclusions: Prevalence of acid peptic disease was found to be very high in the present study. Hence there is a need to institute the preventive and control measures to bring down the prevalence. At the same time the people in the surroundings should be made aware of this health problems and its risk factors.