bluuebunny/crossref_metadata_2025 huggingface dataset:
Language Learning Strategies, Styles and Academic Achievement in English of Elementary Learners: Basis for Reading Program Intervention
Authors: Brenda D. Niebres  , John N. Cabansag
Published: September 2024

This study was conducted to determine the learning styles and language learning strategies used by elementary learners and how these two factors are related to their academic achievement in English. It was conducted in the north cluster of elementary schools of the Schools Division of Santiago City in the School Year 2023-2024. The respondents were the 325 learners of Grades 4 to 6 selected using a 95% degree of confidence and 5% allowable error and distributed to schools chosen using a proportionate allocation formula. It used the descriptive-correlational research design wherein data were gathered through the adapted survey questionnaires of 2019 VARK Learning Styles and the Language Strategy Use Survey from Cohen et al. (2019), validated by the panel of experts. Data were analyzed using descriptive statistics, t-test, and Kendall’s tau-b correlation. Results showed that elementary learners were acquiring language learning strategies; they preferred kinesthetic, read/write, and auditory learning styles. There was no significant difference between male and female pupils in their language learning strategies and learning styles. Learning styles had no bearing on the use of language learning strategies; however, language learning strategies made profound contributions to academic achievement. This study concluded that learning styles and language learning strategies can help learners succeed academically. Hence, it is highly recommended that the proposed reading intervention program be used by teachers implementing catch-up Fridays, with consideration of the learning styles and language learning strategies of learners. Future studies will be undertaken with the results of this study as a reference.
DESIGN, DEVELOPMENT AND PERFORMANCE EVALUATION OF A LOW-COST AND SUSTAINABLE HOUSEHOLD WATER TREATMENT SYSTEM
Authors: Idi Mohammed D. , Akinmusere Oluwaseun K. , Akanni Ayotunde Oluyemisi , Bolorunduro Kehinde A. , Olayanju Opeyemi K. , Williams Bello Ufuoma. P. , Abah James Ugbedeojo , Oke Isaiah A.
Published: September 2024

This study designed, fabricated and evaluated a household water treatment system (HWTS) with a primary aim of improving access to potable water. Typical turbid water samples were collected from Opa River in Ile-Ife, Nigeria. The collected turbid water samples were subjected to treatment by the fabricated household water treatment system. Effects of selected operational factors on the performance of the system was evaluated and optimized using Taguchi technique. The optimum values of the factors were utilized for the full treatment of typical water samples using the system and similar system available commercially. The performance of the system was based on the ability to remove the pollutant from the turbidity water samples. Cost analysis was conducted for the fabricated household water treatment system and similar types that are commercially available. The study revealed that the performance of the system was between 98.8% and 100 % with an overall performance of 99.5 %. Time of settlement, pore Size of the filter, Concentration Coagulant and Turbidity of the Raw water had impact on the performance of HWTS. Significance of the factors were in-order of pore Size of the filter > time > Concentration Coagulant and > Turbidity of the raw water. It was concluded that the performance of the HWTS was perfect compared with the commercially available filter. The HWTS is economically effective and sustainable (0.0575 US$ per day) compared to commercially available HWTS (0.0639 – 0.1187 US$ per day). There was no significant difference between the performance (individual and overall) of fabricated...
The effect of nutrition education based on DASH diet on dietary knowledge among patients with hypertension
Authors: Larasati Clarisa Devi , Yulian Vinami
Published: September 2024

Background: Hypertension is a non-communicable disease with a relatively high prevalence and numerous complications that threaten sufferers. The primary cause of hypertension is the lack of knowledge among patients, leading to uncontrolled consumption of foods high in saturated fats and sodium. Therefore, education on hypertension diet control, such as the DASH diet, is necessary. Increasing knowledge is important because the higher the knowledge, the greater the motivation of hypertension patients to take care of their health.
Purpose: To know the effectiveness of nutrition education based on DASH diet on dietary knowledge among patients with hypertension.
Method: A one-group quasi-experimental pretest-posttest study. The population consisted of 10 individuals with hypertension in Ngrombo Village. The intervention was in the form of DASH diet education program covering 5 variables according to the Indonesian Nursing Outcome Standards. A questionnaire consisting of 25 statements with responses marked in the "yes" or "no" checkboxes was used with a total possible score of 0 to 25 points. The intervention was conducted for 45 minutes. Data were collected before and after the intervention as pre-test and post-test data. The Wilcoxon Signed Rank test was then employed to analyze the collected data.
Results: There is an effect of DASH diet education on the knowledge level of the hypertension diet in hypertension patients, with the Wilcoxon Signed Rank test showing an Asymp.Sig value of < 0.05.
Conclusion: The DASH diet intervention in nursing interventions can significantly increase knowledge about the DASH diet for hypertension patients. Health education on the DASH diet is an intervention that can improve knowledge.
Association between duration of gadget use and social development in school-age children
Authors: Yuswandi Yuswandi , Musri Musri , Resiani Bunga , Gustryanti Kiki
Published: September 2024

Background: The prevalence of school-age children who have gadgets is around 71%, and as many as 55% of them spend time playing these gadgets by playing games. In this sophisticated age, children often focus more on gadgets so if you use gadgets excessively, it will have an impact on children's social development.
Purpose: To determine the relationship between gadget use and social development in school-age.
Method: A cross-sectional study was used for this study. The sample was school-age children (10-12 years) at Elementary School—100 people who were obtained through the total sampling technique. A questionnaire was performed for data collection. The data were analyzed by the Chi-Square statistical test.
Results: The results indicate that most of the participants had higher scores on using the gadgets with a long category (67%). However, almost half of the participants had social development with the adequate category (62%). The results of the statistical test obtained p value = 0.005 < ɑ 0.05.
Conclusion: There is a significant relationship between gadget use and social development among school-age at Elementary School.
 it can be concluded that there is a significant relationship between gadget use and social development among school-age at Elementary School.
The effectiveness of education video and booklet media in knowledge of fluid restrictions among patients with chronic kidney disease
Authors: Sutoyo Ronggo Adi , Maliya Arina
Published: September 2024

Background: The effects of chronic kidney disease (CKD) is fluid retention caused by excessive fluid intake. Lack of knowledge about fluid restriction can be the cause of fluid retention. Health education interventions can overcome this problem because having good knowledge about fluid restriction can affect the success of hemodialysis therapy.
Purpose: To determine the effectiveness of education video and booklet media in knowledge of fluid restrictions among patients with chronic kidney disease.
Method: The research uses a quasi-experimental design with the two groups pre-test post-test design. The population was CKD patients undergoing hemodialysis (HD). Sample is based on the inclusion and exclusion criteria that have been built and the sample is 30 HD patients.
Results: Based on independent sample t-test test, the p value was 0.001 (<0.05) so it can be concluded that there is a difference between interventions with booklet and video.
Conclusion: Fluid restriction education to CKD patients undergoing hemodialysis with booklet and video had an effect on the leveled of patient knowledge which characterized by an increased in post-tested scores compared to the pre-tested. There was a difference in influenced between fluid restriction education for patients with CKD undergoing hemodialysis with booklet and video where booklet media is more effective than video.
Deux minutes et quatorze secondes. Une exécution de Juifs filmée en 1941 et son usage dans les documentaires d’histoire
Authors: Clerc Jean-Benoît
Published: September 2024

Eté 1941 sur une plage de la mer baltique. Le clair soleil, le sable, l’eau, le vent. Des gens se baignent et font des cabrioles dans l’eau, flirtent, jouent et badinent sur la plage. Quelques heures plus tard, au même endroit, dans des fosses creusées au pied d’anciennes fortifications russes en face de la mer, on amène d’autres gens pour y être fusillés. Les personnes qui se baignaient dans la mer et jouaient sur le sable peu avant assistent à la scène. Un sergent de la marine allemande, Reinhard Wiener, filme. Son très court métrage apparaît systématiquement dans les documentaires télévisuels d’histoire qui traitent de la destruction par fusillade des juifs d’URSS durant la Seconde guerre mondiale, où il est associé à des événements qui lui sont étrangers par la date et le lieu. Dans cet ouvrage, l’auteur examine le court-métrage de Reinhard Wiener, le seul film qui nous est parvenu, des exécutions par fusillades des Juifs. Les premières pages sont dévolues à une description du film comme objet matériel, ainsi qu’à l’analyse de ce qu’il montre. S’ensuit une présentation du contexte historique général, à savoir la destruction par fusillade des juifs lors de l’opération Barbarossa, dans certaines villes lettones plus particulièrement. La question de l’usage de ce film par les réalisateurs de films documentaires, des années 1960 aux années 2000 fait également l’objet d’une analyse approfondie. La dernière partie de l’ouvrage est consacrée aux éléments traitant de l’auteur du film, du lieu et de la date du filmage et enfin de l’histoire du film.
Krakowska Empiryczna Szkoła Ekonomiki i Zarządzania Przedsiębiorstwem: geneza – rozwój – osiągnięcia
Authors: Borowiecki Ryszard , Jaki Andrzej
Published: September 2024

Celem artykułu jest prezentacja i egzemplifikacja genezy oraz przeobrażeń organizacyjnych podmiotów tworzących krakowskie środowisko nauk o zarządzaniu – ze szczególnym uwzględnieniem Krakowskiej Empirycznej Szkoły Ekonomiki i Zarządzania Przedsiębiorstwem, a funkcjonujących w strukturze obecnego Uniwersytetu Ekonomicznego w Krakowie oraz jego poprzedników. W artykule ukazano strukturę podmiotową oraz zakresy realizowanych badań, jak również procesy rozwoju i kształcenia kadr naukowych wraz z wyeksponowaniem dorobku naukowych mistrzów oraz kolejnych pokoleń ich uczniów. W ramach podsumowania wyeksponowano kluczowe z punktu widzenia obecnej perspektywy czasowej osiągnięcia zespołu badawczego skupionego w ramach Katedry Ekonomiki i Organizacji Przedsiębiorstw Uniwersytetu Ekonomicznego w Krakowie, będącej kontynuatorką dzieła Krakowskiej Empirycznej Szkoły Ekonomiki i Zarządzania Przedsiębiorstwem. Tworzywem dla powstania artykułu była analiza i ocena literatury, obejmującej także publikacje ukazujące historię Uniwersytetu Ekonomicznego w Krakowie oraz dorobek jego jednostek i tworzących je osób, jak również publikacje o charakterze okolicznościowym i wspomnieniowym.
Zarządzanie oparte na dowodach naukowych w procesie podejmowania decyzji menadżerskich
Authors: Jabłoński Marek , Jabłoński Adam , Dulęba Daniel , Janulek Piotr , Glenszczyk Mariusz
Published: September 2024

Artykuł prezentuje wyniki badań opartych na zastosowaniu metodyki przeglądu literatury przedmiotu w zakresie relacji jaka zachodzi między systemem podejmowania decyzji a zastosowaniem dużych zbiorów danych. W wyniku przeprowadzonych badań oraz analiz zaproponowano autorski model wykorzystania koncepcji evidence-based practice w systemie podejmowania decyzji menadżerskich. Na podstawie przeprowadzonych badań i analiz wskazano, że koncepcja evidence-based practice dotycząca zarządzania opartego na dowodach rozumianych jako wiedza uzyskaną z badań naukowych może z powodzeniem służyć do wspierania menadżerów w procesach podejmowania decyzji biznesowych i może stanowić nowatorskie podejście do zarządzania współczesnymi przedsiębiorstwami. W oparciu o analizę wyników wskazano na to, iż zaproponowana w artykule koncepcja zarządzania oparta na dowodach naukowych powinna znacząco wpływać i być wykorzystywana przez menadżerów do podejmowania decyzji. Innymi słowy wyniki badań naukowych nie musza być prowadzone tylko przez naukowców, ale w dobie dostępu do narzędzi systematycznego przeglądu literatury i dużych zbiorów publikacji naukowych w tym literatury szarej mogą być prowadzone przez zespoły ekspertów zajmujących się analityką na potrzeby poszukiwania optymalnych danych do podjęcia skutecznych i efektywnych decyzji biznesowych. W ten sposób w obszarze nauki o zarządzaniu i jakości może nastąpić szybsza integracja aktywności naukowej z potrzebami wynikającymi z rozwoju i wzrostu biznesu. Podobnie jak w medycynie koncepcja zarządzania dowodowego może przyczyniać się do znaczącego postępu w diagnozowaniu problemów i ich rozwiązywaniu metodami naukowymi.
Financial Performance Measurement with MAIRCA Method: Application on Turkish Banking Sector
Authors: Kavas Yusuf Bahadır , Medetoğlu Batuhan
Published: September 2024

In this study, financial performance measurement was carried out using 8 financial ratios of 11 banks with total assets of 1% or more in 2021. The financial ratios of the banks between 2014 and 2021 were obtained and the analysis was carried out using the MAIRCA method. As a result of the analysis, the financial performance of the banks was ranked and reported between the sample years. The study is important in terms of evaluating banks with financial ratios and determining their performance. The results obtained from the study are aimed to provide ideas to managers, researchers, and academics.
Acquired thrombotic thrombocytopenic purpura without detectable anti-ADAMTS13 antibodies: a possible underlying autoimmune mechanism.
Authors: Simon Delphine , Leclercq Mathilde , Joly Bérangère , Veyradier Agnès , Coppo Paul , Benhamou Ygal
Published: September 2024

In up to 25% of patients with acquired TTP, anti-ADAMTS13 antibodies are not identified, the mechanism resulting from ADAMTS13 deficiency remains unidentified (uTTP). In this study, we provide further insights on clinical presentation and outcome of uTTP. In patients with baseline undetectable anti-ADAMTS13 antibodies, usual features of iTTP (young age, cerebral involvement, severe thrombocytopenia) with no other associated context than a history of systemic autoimmune disease or pregnancy, should prompt to consider the diagnosis of iTTP.
Dengue Death Rate Higher Among Women than Men in Bangladesh
Authors: Roney Miah , Mohd Aluwi Mohd Fadhlizil Fasihi
Published: September 2024

Bangladesh saw a dengue epidemic in 2023 that resulted in a significant number of illnesses and fatalities throughout the country. The Directorate General of Health Services (DGHS) reports that there were 3,21,179 confirmed cases of dengue from January to December 2023, with a fatality rate of 0.53%. Most cases and fatalities in 2023 were documented from June to December. In Bangladesh, the prevalence of dengue fever is greater in men than in women, but women also die from the disease at a higher rate than in men. Given the atypical seasonality of the epidemic and the sudden spike in cases early on, it is noteworthy that mosquito and potential hotspot densities were at an all-time high throughout the previous years.
Bangladesh Journal of Infectious Diseases, June 2024;11(1):79-82
Assessing the Potential Impact of CH.1.1 and JN.1 Variants on Bangladesh's COVID-19 Situation: Should Bangladesh be Concerned?
Authors: Mawa Jannatul , Anjum Ramisa , Dewan Syed Masudur Rahman
Published: September 2024

Abstract Not Available
Bangladesh Journal of Infectious Diseases, June 2024;11(1): 76-78
Pre-Service Early Childhood Teachers’ Emotive Reasoning about an Environmental Issue: Using Well-Defined Environmental Cases in Environmental Education
Authors: Sarıbaş Deniz , Çetinkaya Ertan
Published: September 2024

Environmental education should empower learners to internalize the concept that their ecological niche is an integral component of the larger environment, nurturing a moral and ethical understanding of the reciprocity inherent in their relationship with nature. Emotive reasoning is a crucial aspect of this eco-ethical perspective. From this perspective, this study aims to explore pre-service early childhood teachers’ (PECTs) emotive reasoning about an environmental issue. The researchers created a scenario about an environmental issue including ethical dilemmas of protecting wildlife and environment and human needs. The researchers listed nine possible options and asked the participants to choose one or more of these options and elaborate on their responses in their reflections. Fifty-three PECTs participated in this study. The researchers coded the participants’ responses in each category and analyzed the participants’ decision and elaboration levels in their reflections independently. The results indicate an accumulation mostly in the categories of diffusion of responsibility, compassion, anger, and righteous indignation. The results also revealed mostly a high level of judgment and a high and moderate level of elaboration in PECTs’ emotive reasoning. The results suggest that pre-service teacher education should be revised to include well-defined environmental cases to examine pre-service teachers' emotive reasoning, thus increasing their environmental awareness in environmental education. This exploration is also important to understand their emotive reasoning about wildlife issues and enable them to effectively incorporate this understanding into their teaching practices.
Investigating Documentation and Assessment Practices of Early Childhood Teachers
Authors: Elden Aslı , Aras Selda
Published: September 2024

This study aimed to investigate early childhood teachers' experiences of documentation and assessment practices. 15 early childhood teachers were the participants of the study. The data of this study, in which the phenomenological design was utilized, formed semi-structured interviews, and an exploratory nature was followed to underly philosophical presuppositions of the phenomenological approach. The participant teachers' observation and documentation processes and practices, data-driven decision making to guide further plans, and making learning visible through assessment data were the major themes of the findings of this study. It is found that there are important differences in teachers’ assessment practices. Teachers’ use of assessment in their daily routines gives important messages about their professional understanding of teaching and learning. Although observation is a key aspect of teachers’ practices where they mostly conduct during free play times, teachers’ use of observation and assessment data indicate differences. The study concludes with a discussion on suggesting developing teachers’ documentation and assessment skills through effective professional learning.
Data Integrity Attacks and their Impact on Cyber- Physical Power System Control Applications
Authors: Lavanya A. , R Akshaya , Latha D. Sneha , Bhuvanaa V. , Rajkumar K. , Revathi S.
Published: September 2024

This paper explores the vulnerability of two-area Automatic Generation Control (AGC) systems in smart grids to False Data Injection (FDI) attacks. The AGC system is modelled using state space equations, and its stability and performance are scrutinized under typical load variations. Utilizing MATLAB Simulink, various FDI attacks are introduced to assess their characteristics and potential consequences. The study emphasizes the critical significance of understanding diverse FDI attacks within the context of two-area AGC networks, underscoring their potential to induce malfunctions and blackouts. The findings highlight the need for heightened awareness of cybersecurity risks in AGC systems and emphasize the importance of fortifying these systems against potential threats to ensure the continued resilience and reliability of smart grids.
Airfoil selector for fan applications: a multi-fidelity investigation
Authors:   University of Ferrara, Piovan Mattia , Pinelli Michele ,   University of Ferrara, Suman Alessio ,   University of Ferrara, Zanini Nicola ,   University of Ferrara
Published: September 2024

Energy saving is one of the most important milestones of the energy-green transition, for this reason, the fans’ consumers are very interested in upgrading the efficiency and in general, the performance of their products to comply with increasingly strict standards. To do that different strategies can be used, the one proposed inside the work is based on the redesign of the fan’s swirl adjuster blades to increase efficiency reducing the flow losses. An in-house tool, using a low-fidelity approach, is developed to select the best airfoil shape for prescribed flow conditions. The airfoil shape can be selected over a wide range of standard airfoils, i.e. NACA, Nrel, and Gottingen. The baseline swirl adjuster is realized with the same airfoil shape for all the considered stream-tube, while the optimal swirl adjuster has different airfoils for each flow tube, each with a significant increase in lift/drag ratio compared to the original airfoils. To validate the results obtained with the low-fidelity tool the new swirl adjuster is therefore simulated through CFD, which is considered the high-fidelity tool. The effects of the optimization are shown by comparing both the swirl adjuster pressure drop and the flow morphology inside the device.
Investigation on rotating instability in an axial compressor with different inlet reynolds numbers
Authors:   Shanghai Jiao Tong University, Zhang Xinze , Liu Zhenliang ,   Shanghai Jiao Tong University, Yang Zeyuan ,   Shanghai Jiao Tong University, Wu Yadong ,   Shanghai Jiao Tong University, Ouyang Hua ,   Shanghai Jiao Tong University
Published: September 2024

In the near-stall condition, the axial flow compressor experiences an unstable flow phenomenon known as rotating instability (RI), which typically manifests as a broad bulge in the near-wall pressure spectrum, occurring at frequencies lower than blade passing frequency (BPF). It is considered the primary source of other instabilities such as non-synchronous vibration (NSV) and tip clearance noise (TCN), attracting considerable attention from researchers in recent years. This paper conducts a numerical simulation and experimental verification of a high-speed axial compressor to examine flow phenomenon and spectrum characteristics of RI at different inlet Reynolds numbers. The study explores the effects of inlet Reynolds numbers (Re=5.17e6 and Re=2.72e6) achieved by adjusting inlet total pressure of the compressor. Utilizing approaches such as circumferential mode decomposition to assess the frequency spectrum and mode of RI, the study elucidates the RI in association with the unstable flow structures at the blade tip. The findings indicate that: the most significant interference between the tip leakage flow and the blade occurs in the middle chord of the blade. At different Reynolds numbers, variations in the spatial distribution and number of unsteady vortexes lead to distinct peak aliasing patterns that represent RI and RI-blade interaction in the spectrum.
Aerodynamic Performance Analysis of a Novel Geometry-variable Turbine Guide Vane with a Fixed Angle of Attack
Authors:   Shannxi Engineering Laboratory of Turbomachinery and Power Equipment, Institute of Turbomachinery, School of Energy & Power Engineering, Xi’an Jiaotong University, Lian Zhenhui , Wang Xiangyu ,   Shannxi Engineering Laboratory of Turbomachinery and Power Equipment, Institute of Turbomachinery, School of Energy & Power Engineering, Xi’an Jiaotong University, Yang Xing ,   Shannxi Engineering Laboratory of Turbomachinery and Power Equipment, Institute of Turbomachinery, School of Energy & Power Engineering, Xi’an Jiaotong University, Wu Hang ,   Shannxi Engineering Laboratory of Turbomachinery and Power Equipment, Institute of Turbomachinery, School of Energy & Power Engineering, Xi’an Jiaotong University, Feng Zhenping ,   Shannxi Engineering Laboratory of Turbomachinery and Power Equipment, Institute of Turbomachinery, School of Energy & Power Engineering, Xi’an Jiaotong University
Published: September 2024

A geometry-variable turbine technology effectively improves overall thermal-cycle performance of gas turbine engines under multiple operating conditions. The conventional variable turbine technology is rotating the entire vane airfoil to adjust airflow through the turbine passage. In such a way, the inlet angle of attack, however, is changed as well, which induces flow separation over the vane pressure or suction surfaces and thus results in aerodynamic penalty. To avoid excessive aerodynamic losses caused by the variable geometry, a one-way, adjustable geometry of low-pressure turbine guide vanes (flap-type adjustable guide vane) with a fixed angle of attack is proposed. The front portion of the vane is fixed, while the rear portion is rotated together with a rotating shaft, generating a gap between the front and the rear portions as well as a rotating gap at the upper and lower endwalls. This study explores the effects of shape parameters and closure angles on the aerodynamic performance of the vane passages. Results reveal that the newly-proposed configuration is superior to the conventional scheme in aerodynamic performance. At a closure angle of 7.3°, though the mass-flowaveraged total pressure losses at the vane outlet increases, the overall turbine-stage efficiency is higher relative to the conventional configuration. Within the structural parameters explored in this study, a maximum mass flow adjustment range of 20.48 % can be achieved.
Coupled Fluid-structure Aeroelastic Analysis of Turbomachinery Using Conservative Data Transfer Algorithm
Authors:   Beihang University, Du Zhongyu , Du Pengcheng ,   Beihang University, Ning Fangfei ,   Beihang University
Published: September 2024

The thinner blades with high aerodynamic loading in modern fans and compressors become more susceptible to fluid induced vibration, thus affecting the safe operation of the aero-engine. A coupled fluid-structure interaction method which adopts an in-house CFD code and an open-source structure analysis software CalculiX is developed for flutter analysis of turbomachinery. In this method, conservative and accurate data transfer has been realized at the non-matching mesh interfaces between the fluid and solid domain by using a novel interpolation method, and which is based on locally dimensionality reduction and cell surface integration. The comparisons with other commonly used data transfer methods at the fluid and structure interfaces such as consistent interpolation and radial basis functions interpolation have been carried out. The results showed that the proposed method has good performance and robustness in converting the fluid pressure and viscosity stress into the loads of the structure nodes at the coupling interface. Then the coupled fluidstructure interaction method was applied to predict the aeroelastic characteristics of NASA Rotor 67 and STCF4. The aerodynamic damping coefficients attained by the coupled fluid-structure interaction method agree well with the experimental data or the computational results by other researchers, indicating the effectiveness of the proposed interface data transfer method in turbomachinery flutter analysis.
Improvement of Drug Stock Management Using ABC-VED Analysis in a University Hospital
Authors: Taşer Murat , Özban Murat
Published: September 2024

Objective: Hospitals allocate approximately 35% of their budgets to pharmaceutical and material stocks in order to provide uninterrupted health services. For this reason, hospital managers spend a lot of time and effort in order to keep a minimum level of stock so as not to disrupt health service production and thus to better manage the limited resources of the enterprise. The aim of this study is to group the drugs according to their financial value and vital importance. In this way, it is aimed to perform stock management in the least costly, errorfree and effective way.
Method: In the study, data corresponding to one-year (2021) consumption of a total of 1327 items of drugs were analyzed. The total cost is approximately 83 million ₺. In this study, an ABC-VED cross-analysis was performed on the one-year drug consumption data of a university hospital with 853 beds in order to provide an example of a more controlled inventory structure.
Results: According to the results, it is seen that the ratio of drugs in the first category, that is, drugs that are both high cost and vital for the patient, to the total drug item is 38%. The cost of these drugs constitutes 87% of the total cost.
Conclusion: Taking into account the classifications put forward in the study, strict monitoring of a small number of drugs and regular weekly counts will make drug stock management much easier for managers.
Applications of fractional stochastic volatility models to market microstructure theory and optimal execution strategies
Authors: Webb Abe
Published: September 2024

In this paper, we explore the applications of fractional stochastic volatility (FSV) models within the realm of market microstructure theory and optimal execution strategies. FSV models extend traditional stochastic volatility frameworks by incorporating fractional differentiation, allowing for more flexible and realistic representations of asset price dynamics over time. Our investigation begins with an introduction to FSV models, highlighting their ability to capture long-memory effects and volatility clustering observed in financial markets. These models provide a robust framework for understanding market microstructure dynamics, including order flow behavior, price impact functions, and liquidity provision mechanisms. Furthermore, we discuss recent advancements and empirical findings using FSV models, emphasizing their role in uncovering intraday volatility patterns and their implications for trading strategies under varying market conditions. By incorporating these nuanced volatility dynamics, FSV models contribute to the development of optimal execution algorithms that enhance transaction cost efficiency and market stability. The FSV model, when the Hurst exponent H is set to 0.5, effectively reduces to a standard stochastic volatility model. THis nested relationship can be formally demonstrated by considering the FSV model’s general form and showing that for H = 0.5, the fractional Brownian motion BH(t) becomes a standard Brownian motion Wt, thereby aligning the FSV model with traditional models. Overall, our analysis underscores the significance of FSV models in advancing both theoretical insights and practical applications in modern finance, offering new avenues for research in high-frequency trading strategies and market efficiency.
Clinical and genomic characterization of carbapenem-resistant Enterobacterales bloodstream infections in patients with hematologic malignancies
Authors: Chen Yi , Huang Jiangqing , Dong Luyan , Xu Binbin , Li Lei , Zhao Zhichang , Li Bin
Published: September 2024

Background

Carbapenem-resistant Enterobacterales (CRE) bloodstream infections (BSIs) pose a significant risk to patients with hematologic malignancies, yet the distinct features and outcomes of these infections are not thoroughly understood.

Methods

This retrospective study examined the characteristics and clinical outcomes of patients with Enterobacterales BSIs at the Hematology Department of Fujian Medical University Union Hospital from 2018 to 2022. Whole-genome sequencing was conducted on 45 consecutive CRE BSI isolates during this period.

Results

A total of 301 patients with Enterobacterales BSIs were included, with 65 (21.6%) cases of CRE and 236 (78.4%) cases of carbapenem-susceptible Enterobacterales (CSE). CRE infections accounted for 16.9% to 26.9% of all Enterobacterales BSIs, and carbapenem-resistant Klebsiella pneumoniae (CRKP) was the predominant strain. The most frequent sequence type (ST) and carbapenemase among CRKP were ST11 (68.6%) and blaKPC-2 (80.0%), respectively. Perianal infections, multiple infection foci, and a history of multiple hospitalizations, ICU stays, and prior CRE infections were identified as risk factors for CRE BSIs. Patients in the CRE group experienced significantly higher proportions of infection-related septic shock (43.1% vs. 19.9%, P < 0.0003) and 30-day all-cause mortality (56.9% vs. 24.6%, P < 0.0001) compared to those in the CSE group. Patient’s age and disease subtypes, strain subtypes, and antimicrobial treatment regimens significantly influenced survival in patients with CRE BSIs.

Conclusions

CRE BSIs are a frequent complication in patients with hematological malignancies undergoing treatment and are associated with poor survival rates. A comprehensive understanding of risk factors and ongoing surveillance of prevalent strains are essential for the effective management of these infections.
Successful generalization of conceptual knowledge after training to remember specific events
Authors: Houser Troy M. , Resnick Anthony , Zeithamova Dagmar
Published: September 2024

Introduction

Categorization involves grouping information to make inferences and support novel decisions. In the laboratory, category learning tasks commonly involve trial-and-error where participants are instructed to classify stimuli and learn through feedback. Here, we tested across two experiments whether people can acquire category knowledge in an incidental manner by associating category members with other information that itself is structured, and how it compares to acquiring category knowledge directly through feedback-based classification training.

Methods

Subjects were trained to remember specific associations consisting of cartoon animals paired with animal-specific background scenes. Animals presented on forest vs. mountain scenes were members of two prototype-based categories, but this was not conveyed to the participants. Spontaneous category learning was tested by asking participants to guess habitat (mountains, forests) for old and new cartoon animals without feedback.

Results

We found that participants spontaneously acquired category knowledge, showing high categorization accuracy for new animals, comparable to a group that underwent a traditional feedback-based classification training with the same stimuli. Strategy analysis showed that the majority of participants in both groups abstracted the central tendency of the categories, albeit a somewhat larger proportion of subjects relied on memory for specific training exemplars after paired-associate learning. Partial evidence was found for the hypothesis that generalized knowledge emerged at the expense of memory for specific animal-scene associations.

Discussion

The findings show that despite the goal to remember specific information that required differentiation of stimuli within categories, subjects can spontaneously acquire category knowledge, generalizable to novel stimuli in a way comparable to traditional supervised classification training. This work provides new insights into how category learning can proceed under more naturalistic demands.
A case report of a rare genetic mutation (LMNA-C.185G>C, p.Arg62Pro) associated with dilated cardiomyopathy in a Han Chinese child
Authors: Xu Xiaolin , Chang Tianying , Luo Yan , Wang Lisha , Wang Xiaodan , Shi Jiaxin , Liu Aidong , Guo Jiajuan
Published: September 2024

Dilated cardiomyopathy (DCM) remains an enigmatic myocardial disorder characterized either by enlargement of either the left or right ventricle or both and reduced contractility, posing a significant burden on pediatric populations as a leading cause of cardiac-related mortality and morbidity. This paper presents a compelling case of DCM in a Han Chinese child whose genomic analysis unveiled a novel LMNA-C.185G>C (p.Arg62Pro) variant. Over a meticulous 3-year clinical follow-up, spanning ten outpatient consultations and hospital admissions since the initial diagnosis, the patient exhibited a progressive emergence of various cardiac conduction anomalies closely mirroring LMNA-associated phenotypes. Delving into a comprehensive review of the patient's 14-year medical journey and familial history, antecedent signs of muscular dystrophy (MD) predated DCM onset. Familial scrutiny revealed a lineage marred by muscular atrophy, with the patient's maternal grandmother having a history of muscular dystrophy and an episode of DCM, necessitating cardiac transplantation in the patient's uncle at age 37. This scenario illuminates the intricate interplay between LMNA-associated diseases and genetic predisposition. Timely identification of etiological triggers stands paramount in DCM management. Beyond conventional genetic scrutiny, leveraging novel serum biomarkers such as anti-heart muscle antibodies (AHA) remarkably enhanced diagnostic precision. Notably, personalized therapeutic interventions comprising prednisolone regimens and intravenous immunoglobulin infusions precipitated marked amelioration in heart failure symptoms and serum biomarker profiles. It is noteworthy to identify this novel genetic locus within the Han Chinese populace, underscoring the imperative of expanding the LMNA mutation repository within this demographic cohort. Early recognition of clinical manifestations and etiological cues in pediatric DCM heralds a paradigm shift in risk prognostication and individualized therapeutic interventions, underscoring the profound significance of precision medicine in combating rare familial cardiomyopathies.
An algorithm for identifying stratigraphic piles from interpreted boreholes
Authors: Schorpp Ludovic , Straubhaar Julien , Renard Philippe
Published: September 2024

Introduction

The Stratigraphic Pile (SP) is one of the foundation of most geological studies. It represents, in a compact and practical way, a vertical succession of depositional events over geological time. Accurate definition of the SP is crucial for geological modeling, yet challenges arise when relying on borehole data in the absence of clear biostratigraphic indicators or chronostratigraphical data.

Methods

This manuscript introduces an algorithm designed to automatically determine the SP using borehole unit sequences. The algorithm also addresses the complexities associated with incomplete sedimentological records and subjective geological interpretations. The algorithm was tested on various datasets, taking into account differences in the number of boreholes and available information.

Results and Discussion

The efficiency of the algorithm was demonstrated through real-world applications, providing a basis for a comprehensive discussion of its advantages, limitations, and potential applications. The proposed methodology assumes that each borehole contains a single occurrence of a stratigraphic unit, taking into account possible interpretation errors and inconsistencies. The algorithm is capable of: automatically determining one or an ensemble of plausible stratigraphic sequences, identifying potential misinterpreted wells, quantifying the vertical relationships of the stratigraphic units, and assisting in the data preprocessing step and in building the geologic concept of the modeling area. In particular, this ensemble of SPs and identified inconsistencies provide valuable insights into the geological history and concepts for a particular area.

Conclusion

This research contributes to the refinement of geological modeling workflows and provides a valuable tool for automatic refinement of SP selection.
Mendelian randomization analysis and validation supports MEGF9 and MLLT11 as potential targets for the treatment of varicocele and male infertility
Authors: Cai Bin , Sun Dalin , Deng Weimin , Jin Yihan , Zhao Hongle , Xing Dong , Liu Yuanyuan , Jin Baofang
Published: September 2024

Objective

A growing body of research suggests a link between varicocele and male infertility (MI). However, current evidence is mainly based on retrospective studies, which are prone to interference from confounding factors and cannot establish causal relationships. Mendelian randomization (MR) studies on the causal relationship between varicocele and MI are very limited. Therefore, this study conducted a two-sample MR study to elucidate the causal effect between the two.

Methods

Download the data set GSE216907 from the GEO database, and use R software to screen differential genes in normal and varicocele tissue samples. The drug targets of Bu Shen Huo Xue Prescription (BSHXP) were derived from the Herb database. All genetic datasets were obtained using publicly available summary statistics based on individuals of European ancestry from the IEU GWAS database. MR analysis was performed using MR Egger, weighted median (WM) and inverse variance weighted (IVW) methods to assess the causal relationship between exposure and outcome and to validate the findings by comprehensively evaluating the effects of pleiotropic effects and outliers. The renal vein constriction method was used to establish a pathological model of varicocele infertility. The drug was administered continuously for 60 days and the relevant indicators of the rats were observed.

Results

Obtain two therapeutic targets for varicocele through intersection analysis: MEGF9 and MLLT11, and were verified by molecular docking. MR analysis showed that MEGF9 was positively associated with MI (MR Egger, OR: 1.639, 95% CI: 1.124-2.391, P = 0.024; WM, OR: 1.235, 95% CI: 1.003-1.521, P = 0.047). MEGF9 is also positively associated with MI (IVW, OR: 1.35, 95% CI: 1.069-1.705, P = 0.012). Sensitivity analysis showed no heterogeneity and horizontal pleiotropy. The expression of MEGF9 and MLLT11 increased in the varicocele model group, while the expression decreased after treatment with low, medium, and high doses of BSHXP. In addition, the sperm number, motility, morphology, and fertility of rats in the model group were significantly lower than those in the control group (P<0.05). After BSHXP treatment, all indicators were significantly better than those of the model group (P<0.05).

Conclusion

In conclusion, this study indirectly supports that varicocele causes MI. BSHXP inhibiting MEGF9 and MLLT11 may become a potential therapeutic target for alleviating varicocele and MI.
Profit maximization of a wind-integrated deregulated system using V2G techniques and TCSC placement
Authors: Dawn Subhojit , Ramakrishna A. , Ramesh M. , Das Shreya Shree , Rao K. Dhananjay , Cali Umit , Ustun Taha Selim
Published: September 2024

Profit maximization is crucial for both producers and customers in power grids, particularly in deregulated energy markets. By focusing on profit maximization measures, power grids can improve economic viability and sustainability for all stakeholders. The growing demand for electricity in modern civilization poses a significant challenge to the power grid’s ability to meet it. To address these difficulties, the power industry is attempting to integrate renewable sources into existing power facilities. Because of its unpredictable character, the presence of renewable energy in the electricity system becomes increasingly important and adds complexity to the grid. Given the intermittent nature of renewable sources, an energy storage device is required in this scenario. During the low-power use phase, the grid has ample power. Meanwhile, energy storage devices can be utilized to store extra power in the low power demand phase while maintaining the safety and stability of the power network during peak demand periods. V2G (Vehicle-to-Grid) technology is commonly employed to address the uncertainty of renewable resources while maintaining system stability. By using automobiles as transportable storage devices, V2G can make the best use of excess electricity during low-energy hours. Wind energy’s volatility causes imbalances, lowering system profitability. With wind energy integration, power system profitability can be improved by analyzing uncertainties and employing mitigation strategies. To overcome the issue, the research optimizes the use of V2G and TCSC (thyristor-controlled series compensator). V2G permits bidirectional power flow, lowering imbalance pricing (IP) while considering power demand. TCSC can increase the transient stability of transmission lines, hence reducing line faults. TCSC’s involvement in the system increases profitability by lowering congestion expenses. Strategic TCSC placement increases overall profitability. The approach strives to offer efficient, environmentally friendly power at a reasonable price while addressing the needs of both power providers and customers. This study also looks into the effects of V2G mixing on voltage stability, LMP (locational marginal price), and the effectiveness of a TCSC in a deregulated electrical system. MiPower software is used to simulate operation and find the optimal placement of the storage unit within the IEEE 14-bus system.
How does the energy consumption structure affect the green economic development? A spatial impact analysis
Authors: Zhang Shumin , Wang Jing , Guan Jiawei
Published: September 2024

Background

Optimizing the energy consumption structure (ECS) is conducive to promoting the efficiency and quality of regional green economic development (GED). This paper discusses the current situation of green economic development (GED) in China and how optimizing the energy consumption structure (ECS) can promote green economic development (GED).

Methods

A systematic literature search (from January 2013 to July 2024) was conducted using the keywords “green economic development” and “energy consumption structure” in the following databases: Web of Science, Embase, Science Direct, and PubMed. In this paper, the entropy method was used to measure the GED indicator system, Arcgis drawing was applied to show the current status of GED development, and the theme of this paper was investigated by constructing the basic regression model, Spatial Durbin model, mediating effect model, and moderating effect model. Two researchers independently screened and extracted data.

Results

The analysis of empirical tests in 30 provinces yielded the following results: The overall development of China’s GED shows a fluctuating upward trend. However, there is a regional development imbalance, and the development level of the eastern region is significantly higher than that of the central and western regions. The optimization of ECS contributes significantly to the improvement of GED. And the effect of optimizing ECS on GED has an apparent spatial spillover effect. The optimization of ECS in neighboring regions also promotes the increase of GED in the region, and this feature is more obvious in the central and western regions. The spatial effect of ECS optimization on GED is shown as Central Region > Western Region > Eastern Region. The total effect of the upgrading of the energy consumption structure and its impact on surrounding areas is shown in the following regions: Western region > Central region > Eastern region. The analysis of the mechanism effect shows that upgrading industrial structure is the main mechanism for optimizing ECS on GED.

Discussion

The results show that the optimization and upgrading of ECS is the driving force behind the development of GED, and that there is a need to break down barriers between regions to promote the common development of GED, as well as to play a role in the mechanism of industrial structure.