bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Hospitals in Cervical Cancer Prevention
Authors: Susilawati Susie , Ocviyanti Dwiana
Published: May 2019

Objective: To evaluate the role of hospitals in DKI Jakarta on primary and secondary cervical cancer prevention. Method: This was a survey conducted to 25 hospitals, chosen with simple random sampling from 109 hospitals in DKI Jakarta. Questionnaire used for interview contained statements regarding knowledge, attitude and behavior of 117 health care professionals along with identification of facility preparedness for cervical cancer prevention within those 25 hospitals.

Result: The assessment of knowledge shows that all health care professionals (100%) knew that HPV vaccination is used as a primary prevention for cervical cancer. About 98.3% respondent knew HPV vaccine injected intramuscularly. As much as 91.5% of the respondent knew HPV vaccine is given three times either at month 0, 1, 6 or at month 0, 2, 6. About 71.8% respondent knew deltoid as site for vaccine injection. Most of health care professionals (99.1%) knew VIA (visual inspection with acetic acid) can be used for early detection of cervical cancer. About 76.9% respondent knew how to interpret positive VIA results and 60.7% respondent knew how to do VIA test. As much as 93.2% health care professional knew the purpose of Pap test and about 82.1% knew how to do it. From attitude aspect, most of health care professionals (96.6%) agreed in giving HPV vaccination. About 94% of them agreed to do VIA test and about 98.3% agreed in conducting Pap test. From behavioral aspect, most of the respondent (76.9%) offered HPV vaccination to their clients/patients and 62.4% respondent did HPV vaccination. VIA test was offered and conducted by 52.1% and 30.8% of them, respectively. About 86.3% respondent offered Pap test and 71.8% did the Pap test. As many as 75% of female health care professionals who meet the qualification already had a Pap test for themselves, but only 32.5% ever been vaccinated for HPV. From facility aspect, twenty hospitals (80%) in DKI Jakarta offered HPV vaccination with Pap test can be done in all of them. VIA test and colposcopy were only available in eleven (44%) and ten (40%) hospitals respectively.

Conclusion: Most hospitals in DKI Jakarta have health care professionals with good knowledge and attitude in cervical cancer prevention. However, not many have shown expected behavior in the primary prevention. Most hospitals in DKI Jakarta provide facilities for HPV vaccination and Pap test, but only few have VIA facilities and colposcopy.

Keywords: cervical cancer prevention, health care professional, hospital
Complication on Teenage Pregnancy and Related Factors
Authors: Madjid Omo A , Roesman Nanda I S
Published: May 2019

Objective: To evaluate related factors, which contribute to complication of teenage pregnancy. Method: A cross-sectional research by consecutive sampling method was held upon teenager who was having her first pregnancy or had just been having her first child. This research took place at dr. Zainoel Abidin Public Hospital, Banda Aceh, in period of June until November 2012.

Result: By demographic characteristic, we obtained that the majority of complication of teenage pregnancy occur in the age range of 17-19 years old and most are within Sex maturation Rate grade 5. The most common complications are caesarean section, premature rupture of membranes and cephalo-pelvic disproportion. There is a significant relation between antenatal visit conducted in accordance with WHO criteria and economic level with the incidence of complication.

Conclusion: We found significant relation between antenatal visit conducted in accordance with WHO criteria and economic level with the incidence of complication.

Keywords: complications, teenage pregnancy.
HER2/Neu Expression was Different between Benign, Borderline and Malignant Epithelial Ovarian Tumors
Authors: Hadisubroto Yona S. , Suwiyoga Ketut
Published: May 2019

Objective: To determine the difference of HER2/neu expression in benign, borderline and malignant epithelial ovarian tumor.

Method: An analytic cross-sectional study was performed on 49 samples of epithelial ovarian cases which were divided into three groups: twelve cases of benign epithelial ovarian tumor, 9 cases of borderline epithelial ovarian tumor and 28 cases of malignant epithelial ovarian tumor. Paraffin embedded tissue samples was cut, stained with HER2/neu imunohistochemistry and examined in Pathology Laboratory at Sanglah Hospital. The other data was collected from medical record samples. The data was analysed using One Way Anova test and Chi-square test with level of confidence α = 0.05.

Result: There were 13 cases (46.43%) of the HER2/neu over expression in malignant epithelial ovarian tumors, 2 cases (22.22%) of the HER2/neu over expression in borderline epithelial ovarian tumors and 1 case (9.09%) of the HER2/neu over expression in benign epithelial ovarian tumors. With p = 0.048 (p < 0.05), there are differentiation of HER2/neu expression in benign, borderline and malignant epithelial ovarian tumors.

Conclusion: In this study HER2/neu expression was different between benign, borderline and malignant epithelial ovarian tumors.

Keywords: benign epithelial ovarian tumor, borderline epithelial ovarian tumor, HER2/neu, malignant epithelial ovarian tumor, ovarian cancer.
TUMORES QUÍSTICOS MUCINOSOS DE PÁNCREAS. SERIE DE CASOS Visión retrospectiva de pacientes operados por tumores quísticos mucinosos de páncreas en el INCMNSZ
Authors: Mojarro-Cisneros Miguel Ángel , Rojas-García Bertha Karyme , Carillo-Córdova Dulce María , Figueroa-Méndez Rodrigo , Chan Carlos
Published: May 2019

Los tumores de la glándula pancreática se caracterizan en general por su diagnóstico tardío y mal pronóstico. Se pueden clasificar en tumores endocrinos, exocrinos, quísticos, ampulares y periampulares. Las lesiones quísticas del páncreas, aunque se cree que son raras, pueden estar presentes hasta en un 25% de los pacientes basándose en estudios de autopsia, y hasta un 15% de los pacientes basándose en estudios de imágenes transversales. Los tumores quísticos mucinosos ocupan entre el 10% y 40% de los tumores quísticos del páncreas. La lesión compromete predominantemente a mujeres en la quinta década de la vida. Poseen entre 10 a 20% de posibilidades de malignizarse. En el siguiente reporte se presenta una serie de casos clínicos de pacientes diagnosticados con tumor quístico mucinoso y tratados en el Instituto Nacional Ciencias Médicas y Nutrición Salador Zubirán. (INCMNSZ). LUXMÉDICA, AÑO 14, NÚMERO 41, MAYO-AGOSTO 2019, PP 67-74.
Alineación de la evaluación del desempeño individual a la gestión hotelera.
Authors: Leyva Del Toro Caridad
Published: May 2019

La evaluación del desempeño individual en las organizaciones turísticas debe responder al logro de los objetivos estratégicos con el acercamiento del trabajador a las expectativas de la dirección; razón que la obliga a ser oportuna, flexible y dinámica. Este trabajo tiene como problema  resolver la baja  alineación existente entre  los  resultados individuales con los organizacionales en las entidades hoteleras cubanas , por lo que el objetivo de la investigación es mostrar una tecnología y sus aplicaciones para realizar la evaluación del desempeño individual alineada a la evaluación del desempeño organizacional, con una visión integradora, bajo el uso de tendencias reconocidas internacionalmente en este tema como la gestión por competencias, la mejora continua y el autoperfeccionamiento. La metodología utilizada posee un modelo y procedimiento a partir de la tenencia del cuadro de mando integral operativizado en los niveles estratégico, táctico y operativo, lo que se  integra a los indicadores del cargo,  los  procesos y la entidad. A su vez, se conecta el desempeño individual y el desempeño organizacional a través de conductas estratégicas en las competencias laborales (contempladas para los perfiles de cargos) y los objetivos estratégicos organizacionales
ANALISIS PENINGKATAN DAYA MINAT DAN MOTIVASI BELAJAR SISWA MENGGUNAKAN DELTA MULTIMEDIA EDUTAINMENT SEBAGAI MEDIA PENUNJANG PEMBELAJARAN
Authors: Murad Dina Fitria , Saputra Willy Johan Widjaja
Published: May 2019

Professor Toshiko Kinosita stated that Indonesia's human resources are still very weak to support industrial and economic development. The reason is because the government has never put education as the most important priority. Education is not placed as the most important priority because the people of Indonesia, ranging from the layman to politicians and government officials, are only pursuing money pursuits to enrich themselves and never think long. The opinion of the Japanese Waseda University Professor is very interesting to study considering that the Indonesian government is now starting to look at education as a long-term investment, after all this time education has been neglected. One indicator is that the MPR has agreed to prioritize the education budget of at least 20% of the APBN or APBD. This step is an initial awareness of the importance of education as a long-term investment. This study measures the extent to which the correlation and impact of the use of Information Technology in the teaching and learning process on student achievement in SMA Negeri 8 Tangerang. This research also modeled a learning media with Multimedia method which we named Delta Multimedia Edutainment (DME) which is a local web-based learning media school. The target to be achieved is an increase in interest and student achievement in SMA Negeri 8 Tangerang. The results of this study are useful for schools in improving school performance and maintaining the quality of graduates.
STUDI PERBAIKAN JATUH TEGANGAN DAN RUGI DAYA PADA JARINGAN TEGANGAN RENDAH DENGAN PEMBANGUNAN GARDU SISIP TIPE PORTAL
Authors: Azzahra Septianissa , Handayni Oktaria , Auliya Siti
Published: May 2019

In the system of reliability of electric power distribution that is concerned is good and stable voltage quality, because although the continuity of the supply of electrical energy is reliable, but still there will be a voltage drop. Another factor that affects the system voltage change is the power loss caused by the impedance of the conductor channel series, this power loss causes a voltage drop. Consumers who are located far from the service point tend to receive relatively lower stresses, when compared to the voltage received by consumers who are located close to the service center. The existence of a voltage drop on the receiving end pole can cause the network current to be high so that losses that occur in the network increases. To overcome these problems then performed network repair by building substation distribution insertion so as to improve the quality of the voltage and minimize the loss of power on the network. From the calculation of the percentage value of the voltage drop in PT. PLN Area Cikupa before the installation of the substation is 10.6% for the S phase 1 and 11.7% for the S phase 4, the value is not in accordance with SPLN No. 1 of 1995, the tolerance limit of service voltage variation as a result of voltage loss is a maximum of + 5% and a minimum of -10% at the service side. After the installation of the substation was installed, the voltage dropped to 5.1% for the S phase 1 and 6.1% for the S phase 4, where the value was in accordance with the standard.
RANCANG BANGUNG SISTEM PERSEDIAAN DAN DISRTRIBUSI SEPEDA MOTOR MENGGUNAKAN METODE FIFO
Authors: . Marisa
Published: May 2019

Motorbikes supply and distribution is one of the important work activities for the development of PT. Jagat Karya Abadi. In its development, there are many problems arise, such as the difficulties of obtaining fast, precise and accurate inventory information. As for the emergence of these problems is the frequent occurrence of errors in recording motorbike data entry, motorbike demand and motorbike expenditure until the making of reports.The use of technology and computerization are have a big contribute so the tasks and work are carried out properly. It aims to avoid and reduce errors in recording, lack of accuracy, and others. Motorbikes supply and distribution system at PT. Jagat Karya Abadi with the FIFO method is one solution to overcome existing problems. The inventory and distribution system at PT Jagat Karya Abadi implements PHP programming languages, database and MySQL.
Studi Literatur Basis Data SQL dan NoSQL
Authors: Suliyanti Widya Nita
Published: May 2019

With the increasing need to store large amounts of unstructured and semi-structured data, the database that used to be mostly using SQL technology, began using the NoSQL database. The purpose of this paper is to conduct a literature study of the characteristics, advantages and disadvantages of SQL and NoSQL databases. This literature study shows that there are differences in SQL databases and based on characteristics (ACID for SQL vs. BASE and CAP for NoSQL); data model (relational for SQL and key-value for NoSQL); data structure (structured for SQL and non- or semi-structured for NoSQL); process (subquery, join and grouping / aggregation and complex queries faster only for SQL); and the number of servers used (single large server for SQL and multiple multiple levels for NoSQL). A literature review for further SQL and NoSQL applications is needed in the future.
Patrimonio concurrente. La necesidad de la gestión conjunta en el patrimonio arqueológico en la provincia de Cádiz
Authors: Mateos Orozco Ana
Published: May 2019

La provincia de Cádiz tiene una enorme riqueza patrimonial en todos los sentidos. Sin embargo, la inexistencia de políticas de gestión comunes dificulta el entendimiento de elementos patrimoniales que podemos considerar concurrentes, estrechamente ligados y con significados comunes. La comprensión de estos elementos de manera conjunta supondría además la creación de paisajes más diversos, con historias e identidades compartidas. Las agendas urbanas de Andalucía proponen el trabajo común, con el objetivo de equilibrar las diferentes zonas de Andalucía, en la búsqueda de un desarrollo más sostenible y eficaz. Su aplicación en la provincia, de manera conjunta, podría suponer una enorme cantidad de beneficios en la gestión de estas localidades sin necesidad de proponer medidas arriesgadas.
El “amable” urbanismo de mercado. Patrimonio e identidad como elementos competitivos fundamentales
Authors: Martínez Castizo Daniel
Published: May 2019

Las Agendas Urbanas se enmarcan dentro de los 17 Objetivos de Desarrollo Sostenible (ODS) que recoge la Agenda 2030. El documento, nacido en la Cumbre Mundial sobre el Desarrollo Sostenible de Nueva York (septiembre de 2015), se marca como objetivo “lograr que las ciudades y los asentamientos humanos sean inclusivos, seguros, resilientes y sostenibles”. Los principios propuestos para alcanzar estas metas no dejan de ser similares a los aplicados en otros territorios, como el rural, en los que la mercantilización del patrimonio cultural y natural terminó por ser el eje sobre el que giraron todos los proyectos. En ese sentido, la ejecución de Agendas Urbanas, bajo los mismos parámetros y principios del sistema, pretenden generar un “amable” urbanismo de mercado” en el que patrimonio e identidad pasan a convertirse en simples ventajas comparativas.
INTAKE ASSESSMENT OF SMALL DOSES OF MERCURY IN THE HUMAN BODY WITH FOOD
Authors: Gorbunov A V , Lyapunov S M , Okina O I , Sheshukov V S
Published: May 2019

The aim of this work was to assess mercury content in food products and intake in the human body in Russia. Sampling was carried out on the territory of Russia without reference to the manufacturer in accordance with the principle of random sampling. The analysis of mercury concentrations in a wide range of food and agricultural products was carried out by atomic absorption with "cold vapor". On the basis of this analysis we identified foods with the highest and lowest concentrations of mercury. According to the literature data a number of food products consumable by people with different income levels and at an average for the regions of Russia has been estimated. Daily intake of mercury in the human body according to this regiment has been calculated. A comparison of the actual mercury intake in the human body with safety daily dose has been made according to the FAO and WHO. Mercury dose intaking in the human body with fish and fish products has been also calculated. It is shown that the mercury intake in the human body with food products ranges within acceptance limits in Russia. However, there is a low-dose mercury intake typical for the entire population of Russia.
THE ROLE OF HYDROBIONTS AND BACTERIAL BIOFILMS IN SURVIVABILITY OF SAPROZOONOSES IN THE MARINE ECOSYSTEM (Literature Review)
Authors: Eskova A I , Buzoleva L S , Krivosheeva A M
Published: May 2019

This review presented the problem of saprozoonoses survivability in the marine environment. It is shown that hydrobionts is one of the major infection transmission factors. But the marine environment is unfavorable for existence of pathogenic bacteria; therefore, one of the important issues is mechanisms disclosure allowing to explain the continued existence of pathogenic bacteria in the marine environment. Experimental studies on aquatic organisms, reflecting the coping mechanisms of pathogenic bacteria in the marine environment have been discussed. Information concerning processes of marine bacteria biofilm formation has been stated. It is shown that biofilms can be formed by bacteria of one type or form a community of developing from many species of microorganisms, such as bacteria, protozoa, fungi or algae. It is noted that in the natural habitats biofilms can cause serious environmental deterioration, since they are difficult to destroy. The literature review showed that the pathogenic bacteria survivability in the marine environment is possible due to development of a wide range of different hosts (microalgae, plants, mollusks, protozoans, crustaceans, etc.), as well as due to the formation of biofilms as mono- and mixed options on various surfaces, contributing to the preservation of their viability.
Rasprostranennost' oslozhneniy sakharnogo diabeta 2 tipa i soputstvuyushchikh zabolevaniy v gorode Almaty Respubliki Kazakhstan v 2012-2016 godakh
Authors: Tazhiyeva A E , Reznik V L , Ivanov S V , Grjibovski A M
Published: May 2019

We analyzed the prevalence of complications of type 2 diabetes mellitus and concomitant diseases in Almaty, Kazakhstan for the period 2012-2016. Statistically significant trends in the prevalence of nephropathy (from 4.0 to 2.2 per 10 000 population), retinopathy (from 12.7 to 7.5 per 10 000 population) and sensory neuropathy (from 14.0 to 10.1 per 10 000 population) were revealed, as well as trends in the reduction in the prevalence of angina pectoris, myocardial infarction, cerebrovascular diseases among type 2 diabetes patients. Downward trends in the incidence of disability due to myocardial infarction, cerebral circulation disorders, vision loss and nephropathy were observed as well. Districts of the Almaty city with the most unfavorable epidemiological situation in relation to complications of type 2 diabetes mellitus were identified. There was no association between the number of internal medicine specialists or endocrinologists and the prevalence of complications of type 2 diabetes in the city.
INFLUENCE OF JOB ANALYSIS (JOB ANALYSIS) ON EMPLOYEE PERFORMANCE AT PT. HAYATI PRATAMA MANDIRI WEST SUMATRA
Authors: Faesal Hendri , Lukito Hendra
Published: May 2019

This study aims to determine and analyze the Effect of Job Analysis (Job Analysis) On Employee Performance On PT.Hayati Pratama Mandiri West Sumatra. This research is exploratory research with research sample that is as much as 186 people. This study uses multiple regression analysis with the help of SPSS program version 22.00 with the results of research that is 1) Job description has a positive and significant impact on employee performance in PT.Hayati Pratama Mandiri West Sumatra. The better the existing job description, it will improve the performance of employees of PT. Hayati Pratama Mandiri, 2) Job specifications have a positive and significant impact on employee performance. The more exact job specification which means that each job has the exact requirements specifications and employees obtained in accordance with the specified specifications, it will improve the performance of employees PT.Hayati Pratama Mandiri, and 3) Job evaluation has a positive and significant impact on employee performance at PT. Hayati Pratama Mandiri. The better performing job evaluation will improve employee performance.
Effect of Row Cleaner Operational Settings on Crop Residue Translocation in Strip-Tillage
Authors: Lekavičienė Kristina , Šarauskis Egidijus , Naujokienė Vilma , Kriaučiūnienė Zita
Published: May 2019

Through field experiments and empirical analysis methods, this study determined the dependence of plant residue removal on the row cleaner’s settings in strip-tillage. The main research object of this study is row cleaners. By changing the slip angles (10, 15, and 22.5°), the gap between row cleaner discs in parallel (165, 180, and 195 mm), and the driving speed (1.3, 1.9, 2.5, and 3.1 m s−1), we determined what percentage of wheat residue was removed from the strip on the surface of the soil and what distance it was moved. The percentage of removed plant residue was determined by evaluating the differences between the masses of the plant residue taken from non-removed and removed strips. Empirical analysis of the results of the field experiments showed that both the amount of the removed plant residue and the distance it is moved to were the best when the slip angle was 15°, the gap between the discs of row cleaner was 180 mm, and the driving speed was 2.5 m s−1. With these parameters, up to three-quarters of the plant residue was removed from the soil surface of the strip, which was relocated 308 mm from the middle of the strip. If the slip angle and the driving speed are increased further, even more plant residue can be removed; however, if the plant residue is relocated too far away, it may fall into the zone of the adjacent strip.
Antioxidant Activity and Anthocyanin Contents in Olives (cv Cellina di Nardò) during Ripening and after Fermentation
Authors: Aprile Alessio , Negro Carmine , Sabella Erika , Luvisi Andrea , Nicolì Francesca , Nutricati Eliana , Vergine Marzia , Miceli Antonio , Blando Federica , De Bellis Luigi
Published: May 2019

The olive tree “Cellina di Nardò” (CdN) is one of the most widespread cultivars in Southern Italy, mainly grown in the Provinces of Lecce, Taranto, and Brindisi over a total of about 60,000 hectares. Although this cultivar is mainly used for oil production, the drupes are also suitable and potentially marketable as table olives. When used for this purpose, olives are harvested after complete maturation, which gives to them a naturally black color due to anthocyanin accumulation. This survey reports for the first time on the total phenolic content (TPC), anthocyanin characterization, and antioxidant activity of CdN olive fruits during ripening and after fermentation. The antioxidant activity (AA) was determined using three different methods. Data showed that TPC increased during maturation, reaching values two times higher in completely ripened olives. Anthocyanins were found only in mature olives and the concentrations reached up to 5.3 g/kg dry weight. AA was determined for the four ripening stages, and was particularly high in the totally black olive fruit, in accordance with TPC and anthocyanin amounts. Moreover, the CdN olives showed a higher TPC and a greater AA compared to other black table olives produced by cultivars commonly grown for this purpose. These data demonstrate the great potential of black table CdN olives, a product that combines exceptional organoleptic properties with a remarkable antioxidant capacity.
Erigeron annuus (L.) Pers. Extract Inhibits Reactive Oxygen Species (ROS) Production and Fat Accumulation in 3T3-L1 Cells by Activating an AMP-Dependent Kinase Signaling Pathway
Authors: Choi Yoon-Hee , Lee Ok-Hwan , Zheng Yulong , Kang Il-Jun
Published: May 2019

Obesity is one of the major public health problems in the world because it is implicated in metabolic syndromes, such as type 2 diabetes, hypertension, and cardiovascular diseases. The objective of this study was to investigate whether Erigeron annuus (L.) Pers. (EAP) extract suppresses reactive oxygen species (ROS) production and fat accumulation in 3T3-L1 cells by activating an AMP-dependent kinase (AMPK) signaling pathway. Our results showed that EAP water extract significantly inhibits ROS production, adipogenesis, and lipogenesis during differentiation of 3T3-L1 preadipocytes. In addition, EAP decreased mRNA and protein levels of proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer-binding protein alpha (C/EBPα). Moreover, EAP suppressed mRNA expressions of fatty acid synthase (FAS), lipoprotein lipase (LPL), adipocyte protein 2 (aP2) in a dose-dependent manner. Whereas, EAP upregulated adiponectin expression, phosphorylation levels of AMPK and carnitine palmitoyltransferase 1 (CPT-1) protein level during differentiation of 3T3-L1 preadipocytes. These results suggest that EAP water extract can exert ROS-linked anti-obesity effect through the mechanism that might involve inhibition of ROS production, adipogenesis and lipogenesis via an activating AMPK signaling pathway.
Investigation of the Influence of Splitter Blades on the Resonance Conditions of Impellers
Authors: Liu Kaicheng , Yan Cheng
Published: May 2019

The conventional resonance conditions are derived based on the conventionally designed impellers without splitter blades. This paper proposes the resonance conditions for impellers under the excitation from the impeller–diffuser interaction with attention paid on the influence of splitter blades. A lumped parameter model is established and the modal analysis is carried out. The blade-based representative modal vector (RMV) is defined. The influence of splitter blades on the impeller’s traits of modes is investigated by analyzing the spatial harmonic contents of the RMV. Then, given the specific form of the diffuser-induced engine order excitation acting on the main and splitter blades, the resonance conditions are derived. Tuned and mistuned cases are provided for a practical impeller. The resonance conditions are verified by harmonic response calculations. The applications of the proposed resonance conditions in resonance identification and hazard evaluation of different excitations are given. The differences between the proposed resonance conditions and the conventional ones are discussed. The research indicates that even the RMV of the tuned impeller contains two harmonic components due to the existence of splitter blades. When the excitation frequency equals the natural frequency of the impeller and the excitation order matches with either harmonic index of the two harmonics, the resonance occurs. The results of case studies show that the harmfulness of various engine orders of excitation can be exactly evaluated by the joint use of the spatial harmonic contents analysis result and the proposed resonance conditions; however, analyzing based on the conventional resonance conditions may lead to the misjudgment of the harmfulness of the excitations.
Advances in Spectral Distribution Assessment of Laser Accelerated Protons using Multilayer CR-39 Detectors
Authors: Groza Andreea , Serbanescu Mihai , Butoi Bogdan , Stancu Elena , Straticiuc Mihai , Burducea Ion , Balan Adriana , Chirosca Alecsandru , Mihalcea Bogdan , Ganciu Mihai
Published: May 2019

We show that a spectral distribution of laser-accelerated protons can be extracted by analyzing the proton track diameters observed on the front side of a second CR-39 detector arranged in a stack. The correspondence between the proton track diameter and the incident energy on the second detector is established by knowing that protons with energies only higher than 10.5 MeV can fully deposit their energy in the second CR-39 detector. The correlation between the laser-accelerated proton track diameters observed on the front side of the second CR-39 detector and the proton incident energy on the detector stack is also presented. By calculating the proton number stopped in the CR-39 stack, we find out that its dependence on the proton energy in the 1–15 MeV range presents some discontinuities at energies higher than 9 MeV. Thus, we build a calibration curve of the track diameter as a function of the proton incident energy within the 1–9 MeV range, and we infer the associated analytical function as the calculations performed indicate best results for proton spectra within the 1–9 MeV range. The calibration curve is used as a tool to ascertain the pits identified on the surfaces of both CR-39 detectors to proton tracks. The proton tracks spatial distribution analyzed by optical and atomic force microscopy is correlated with the peculiarity of the used targets.
A Sparse Classification Based on a Linear Regression Method for Spectral Recognition
Authors: Ye Pengchao , Ji Guoli , Yuan Lei-Ming , Li Limin , Chen Xiaojing , Karimidehcheshmeh Fatemeh , Chen Xi , Huang Guangzao
Published: May 2019

This study introduces a spectral-recognition method based on sparse representation. The proposed method, the linear regression sparse classification (LRSC) algorithm, uses different classes of training samples to linearly represent the prediction samples and to further classify them according to residuals in a linear regression model. Two kinds of spectral data with completely different physical properties were used in this study. These included infrared spectral data and laser-induced breakdown spectral (LIBS) data for Tegillarca granosa samples polluted by heavy metals. LRSC algorithm was employed to recognize the two classes of data, and the results were compared with common spectral-recognition algorithms, such as partial least squares discriminant analysis (PLS-DA), soft independent modeling of class analogy (SIMCA), artificial neural network (ANN), random forest (RF), and support vector machine (SVM), in terms of recognition rate and parameter stability. The results show that LRSC algorithm is not only simple and convenient, but it also has a high recognition rate.
Cold Argon Plasma as Adjuvant Tumour Therapy on Progressive Head and Neck Cancer: A Preclinical Study
Authors: Hasse Sybille , Seebauer Christian , Wende Kristian , Schmidt Anke , Metelmann Hans-Robert , von Woedtke Thomas , Bekeschus Sander
Published: May 2019

Investigating cold argon plasma (CAP) for medical applications is a rapidly growing, innovative field of research. The controllable supply of reactive oxygen and nitrogen species through CAP has the potential for utilization in tumour treatment. Maxillofacial surgery is limited if tumours grow on vital structures such as the arteria carotis. Here CAP could be considered as an option for adjuvant intraoperative tumour therapy especially in the case of squamous cell carcinoma of the head and neck. Further preclinical research is necessary to investigate the efficacy of this technology for future clinical applications in cancer treatment. Initially, a variety of in vitro assays was performed on two cell lines that served as surrogate for the squamous cell carcinoma (SCC) and healthy tissue, respectively. Cell viability, motility and the activation of apoptosis in SCC cells (HNO97) was compared with those in normal HaCaT keratinocytes. In addition, induction of apoptosis in ex vivo CAP treated human tissue biopsies of patients with tumours of the head and neck was monitored and compared to healthy control tissue of the same patient. In response to CAP treatment, normal HaCaT keratinocytes differed significantly from their malignant counterpart HNO97 cells in cell motility only whereas cell viability remained similar. Moreover, CAP treatment of tumour tissue induced more apoptotic cells than in healthy tissue that was accompanied by elevated extracellular cytochrome c levels. This study promotes a future role of CAP as an adjuvant intraoperative tumour therapy option in the treatment of head and neck cancer. Moreover, patient-derived tissue explants complement in vitro examinations in a meaningful way to reflect an antitumoral role of CAP.
Strong Designated Verifier Signature Scheme with Undeniability and Strong Unforgeability in the Standard Model
Authors: Yang Xiaodong , Chen Guilan , Li Ting , Liu Rui , Wang Meiding , Wang Caifen
Published: May 2019

Strong designated verifier signature can provide an efficient way to protect the identity privacy of the signer and the integrity of the data transmitted over the public channel. These characteristics make it very useful in outsourcing computing, electronic voting, electronic bidding, electronic auction and other fields. However, most strong designated verifier signature schemes are unable to identify the real signature generator when the signer and the designated verifier dispute a signature. In addition, the existing strong designated verifier signature schemes in the standard model rarely satisfy strong unforgeability, and thus cannot prevent the attacker from forging a valid signature on any previously signed message. Therefore, designing a strong designated verifier signature scheme without random oracles that satisfies strong unforgeability and undeniability is very attractive in both practice and theory. Motivated by these concerns, we design the first undeniable strong designated verifier signature scheme without random oracles, in which the arbiter can independently perform the judgment procedure to prove whether a controversial signature is generated by the signer or the designated verifier. Under standard assumptions, the scheme is proved to be strongly unforgeable in standard model. Furthermore, it not only achieves non-transferability and privacy of the signer’s identity but also satisfies the undeniable property of traditional digital signature schemes. Performance analysis results show that the length of the signer’s private key, the designated verifier’s private key and signature length are 40 bits, 40 bits and 384 bits, respectively. Compared with he related schemes, the proposed scheme has higher performance in signature length, private key size and computational overhead. Finally, we show how to apply it to implement outsourcing computation in cloud computing.
An Overview of Construction Occupational Accidents in Hong Kong: A Recent Trend and Future Perspectives
Authors: Shafique Muhammad , Rafiq Muhammad
Published: May 2019

The construction industry is infamous for a high number of fatalities around the world. The Hong Kong construction industry is also one of the most hazardous industries for worker’s safety compared to all other industries. This paper presents a current trend of occupational injuries among Hong Kong construction workers. Yearly reports of the labour department of Hong Kong were evaluated in this study. A statistical analysis of incidence rates (IRs) and mortality rates (MRs) was performed to evaluate each accident type. Moreover, analysis of variance (ANOVA) was performed to find out the relationship between IRs and MRs of individual accident type. From the analysis, “Slip, trip or fall on the same level” caused the higher number of occupational injuries while “fall of the person from height” caused the higher number of occupational fatalities from 2011 to 2017. Finally, the future perspectives of effective safety management system incorporated with advance technologies in the construction industry are highlighted in this study.
Design of a Laparoscopic Robot System Based on Spherical Magnetic Field
Authors: Wei Hongxing , Li Kaichao , Xu Dong , Tan Wenshuai
Published: May 2019

In single incision laparoscopic surgery (SILS), because the laparoscope and other surgical instruments share the same incision, the interferences between them constrain the dexterity of surgical instruments and affect the field of views of the laparoscope. Inspired by the structure of the spherical motor and the driving method of an intraocular micro robot, a fully inserted laparoscopic robot system is proposed, which consists of an inner laparoscopic robot and external driving device. The position and orientation control of the inner laparoscopic robot are controlled by a magnetic field generated by the driving device outside the abdominal wall. The instrumental interferences can be alleviated and better visual feedback can be obtained by keeping the laparoscopic robot away from the surgical incision. To verify the feasibility of the proposed structure and explore its control method, a prototype system is designed and fabricated. The electromagnetism model and the mechanical model of the laparoscopic robot system are established. Finally, the translational, rotational, and deflection motion of the laparoscopic robot are demonstrated in practical experiment, and the accuracy of deflection motion of the laparoscopic robot is verified in open-loop condition.
Performance of SIMO FSO Links over Mixture Composite Irradiance Channels
Authors: Androutsos Nikolaos A. , Nistazakis Hector E. , Stassinakis Argyris N. , Sandalidis Harilaos G. , Tombras George S.
Published: May 2019

Free space optics (FSO) technology has demonstrated an increasingly scientific and commercial interest over the past few years. However, due to signal propagation in the atmosphere, the operation depends strongly on the atmospheric conditions and some random impairments, including turbulence and pointing error (PE) effects. In the present study, a single-input multiple-output FSO system with wavelength, spatial, or time diversity over the turbulence and non-zero boresight PE effects is thoroughly investigated. A versatile mixture composite model which accurately describes both impairments is employed for the performance evaluation. Novel mathematical expressions of the outage probability and the average bit-error rate assuming intensity modulation/direct detection and optimal combining at the reception are provided.
High-Efficiency Coupling Method of the Gradient-Index Fiber Probe and Hollow-Core Photonic Crystal Fiber
Authors: Wang Chi , Zhang Yue , Sun Jianmei , Li Jinhui , Luan Xinqun , Asundi Anand
Published: May 2019

A high-efficiency coupling method using the gradient-index (GRIN) fiber probe and hollow-core photonic crystal fiber (HC-PCF) is proposed to improve the response time and the sensitivity of gas sensors. A coupling efficiency model of the GRIN fiber probe coupled with HC-PCF is analyzed. An optimization method is proposed to guide the design of the probe and five samples of the GRIN fiber probe with different performances are designed, fabricated, and measured. Next, a coupling efficiency experimental system is established. The coupling efficiencies of the probes and single-mode fiber (SMF) are measured and compared. The experimental results corrected by image processing show that the GRIN fiber probe can achieve a coupling efficiency of 80.22% at distances up to 180 μm, which is obviously superior to the value of 33.45% of SMF at the same distance. Moreover, with the increase of the coupling distance, the coupling efficiency of the probe is still higher than that of SMF.
Artificial Intelligence in Intelligent Tutoring Robots: A Systematic Review and Design Guidelines
Authors: Yang Jinyu , Zhang Bo
Published: May 2019

This study provides a systematic review of the recent advances in designing the intelligent tutoring robot (ITR) and summarizes the status quo of applying artificial intelligence (AI) techniques. We first analyze the environment of the ITR and propose a relationship model for describing interactions of ITR with the students, the social milieu, and the curriculum. Then, we transform the relationship model into the perception-planning-action model to explore what AI techniques are suitable to be applied in the ITR. This article provides insights on promoting a human-robot teaching-learning process and AI-assisted educational techniques, which illustrates the design guidelines and future research perspectives in intelligent tutoring robots.
Cultural Tourism: Imagery of Arnhem Land Bark Paintings Informs Australian Messaging to the Post-War USA
Authors: Geissler Marie
Published: May 2019

This paper explores how the appeal of the imagery of the Arnhem Land bark painting and its powerful connection to land provided critical, though subtle messaging, during the post-war Australian government’s tourism promotions in the USA.
Unification Theories: New Results and Examples
Authors: Nichita Florin F.
Published: May 2019

This paper is a continuation of a previous article that appeared in AXIOMS in 2018. A Euler’s formula for hyperbolic functions is considered a consequence of a unifying point of view. Then, the unification of Jordan, Lie, and associative algebras is revisited. We also explain that derivations and co-derivations can be unified. Finally, we consider a “modified” Yang–Baxter type equation, which unifies several problems in mathematics.
Diagnoses in the Aging Process of Residential Buildings Constructed Using Traditional Technology
Authors: Nowogońska Beata
Published: May 2019

The perspective of maintaining residential buildings in adequate technical condition is one of the most important problems over the course of their service life. The aim of the work is to present issues connected with the methods of predicting the process of changes in performance characteristics over the entire period that a building, constructed using traditional technology, is operational. Identification of the technical situation consists of a prognosis based on the analytical form of the distribution function and probability density of building usability. The technical condition of a building results from its past, while familiarity with the condition is necessary to determine how the building will behave in the future. The presented predictive diagnostics of the performance characteristics of an entire building and its elements is an original methodology of describing the lifespan of a building. In addition to identifying the technical condition, its aim is also to aid in making decisions regarding maintenance works. The developed model of predicting changes in the performance characteristics of buildings, the Prediction of Reliability according to Exponentials Distribution (PRED), is based on the principles applied for technical devices. The model is characterized by significant limitations in its application due to the negligible influence of wear processes. In connection with the above, the Prediction of Reliability according to Raleigh Distribution (PRDD) was developed, where the carried-out processes of changes in the performance characteristics are described using Rayleigh’s distribution, and the building is a multi-element system. Model development would be incomplete without subjecting it to verification. Predicting the degree of the technical wear of load-bearing walls of a building is a form of checking the proposed PRED and PRRD models on the basis of data derived from periodical inspections of the research material. The developed model of the time distribution of the proper functioning of a building, presented as an image of the forecast of changes in the technical condition, can be applied to solving problems occurring in practice. The targeted approach to predicting the occurrence of damage will allow for optimal planning of maintenance works in buildings during their entire service life.
New Insights into Molecular Oncogenesis and Therapy of Uveal Melanoma
Authors: Violanti Sara , Bononi Ilaria , Gallenga Carla , Martini Fernanda , Tognon Mauro , Perri Paolo
Published: May 2019

Uveal melanoma (UM), which is the most common cancer of the eye, was investigated in recent years by many teams in the field of biomedical sciences and eye clinicians. New knowledge was acquired on molecular pathways found to be dysregulated during the multistep process of oncogenesis, whereas novel therapeutic approaches gave significant results in the clinical applications. Uveal melanoma-affected patients greatly benefited from recent advances of the research in this eye cancer. Tumour biology, genetics, epigenetics and immunology contributed significantly in elucidating the role of different genes and related pathways during uveal melanoma onset/progression and UM treatments. Indeed, these investigations allowed identification of new target genes and to develop new therapeutic strategies/compounds to cure this aggressive melanoma of the eye. Unfortunately, the advances reported in the treatment of cutaneous melanoma have not produced analogous benefits in metastatic uveal melanoma. Nowadays, no systemic adjuvant therapy has been shown to improve overall survival or reduce the risk of metastasis. However, the increasing knowledge of this disease, and the encouraging results seen in clinical trials, offer promise for future effective therapies. Herein, different pathways/genes involved in uveal melanoma onset/progression were taken into consideration, together with novel therapeutic approaches.
Biotransformation with a New Acinetobacter sp. Isolate for Highly Enantioselective Synthesis of a Chiral Intermediate of Miconazole
Authors: Miao Yanfei , Liu Yuewang , He Yushu , Wang Pu
Published: May 2019

(R)-2-Chloro-1-(2,4-dichlorophenyl) ethanol is a chiral intermediate of the antifungal agent Miconazole. A bacterial strain, ZJPH1806, capable of the biocatalysis of 2-chloro-1-(2,4-dichlorophenyl) ethanone, to (R)-2-chloro-1-(2,4-dichlorophenyl) ethanol with highly stereoselectivity was isolated from a soil sample. It was identified as the Acinetobacter sp., according to its morphological observation, physiological-biochemical identification, and 16S rDNA sequence analysis. After optimizing the key reaction conditions, it was demonstrated that the bioreduction of 2-chloro-1-(2,4-dichlorophenyl) ethanone was effectively transformed at relatively high conversion temperatures, along with glycerol as cosubstrate in coenzyme regeneration. The asymmetric reduction of the substrate had reached 83.2% yield with an enantiomeric excess (ee) of greater than 99.9% at 2 g/L of 2-chloro-1-(2,4-dichlorophenyl) ethanone; the reaction was conducted at 40 °C for 26 h using resting cells of the Acinetobacter sp. ZJPH1806 as the biocatalyst. The yield had increased by nearly 2.9-fold (from 28.6% to 83.2%). In the present study, a simple and novel whole-cell-mediated biocatalytic route was applied for the highly enantioselective synthesis of (R)-2-chloro-1-(2,4-dichlorophenyl) ethanol, which allowed the production of a valuable chiral intermediate method to be transformed into a versatile tool for drug synthesis.
A Case Study for the Deactivation and Regeneration of a V2O5-WO3/TiO2 Catalyst in a Tail-End SCR Unit of a Municipal Waste Incineration Plant
Authors: Cimino Stefano , Ferone Claudio , Cioffi Raffaele , Perillo Giovanni , Lisi Luciana
Published: May 2019

In this work, we set out to investigate the deactivation of a commercial V2O5-WO3/TiO2 monolith catalyst that operated for a total of 18,000 h in a selective catalytic reduction unit treating the exhaust gases of a municipal waste incinerator in a tail end configuration. Extensive physical and chemical characterization analyses were performed comparing results for fresh and aged catalyst samples. The nature of poisoning species was determined with regards to their impact on the DeNOx catalytic activity which was experimentally evaluated through catalytic tests in the temperature range 90–500 °C at a gas hourly space velocity of 100,000 h−1 (NO = NH3 = 400 ppmv, 6% O2). Two simple regeneration strategies were also investigated: thermal treatment under static air at 400–450 °C and water washing at room temperature. The effectiveness of each treatment was determined on the basis of its ability to remove specific poisoning compounds and to restore the original performance of the virgin catalyst.