bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Solid and Liquid Extracts of Lombok Sargassum cristafolium on Growth and Yield of Rice Plants (Oryza sativa L.)
Authors: Sunarpi Haji , Nikmatullah Aluh , Sunarwidhi Anggit L. , Ambana Yogi , Ilhami Bq Tri Khairina , Widyastuti Sri , Hernawan Ari , Prasedya Eka Sunarwidhi
Published: October 2020

An exessive use of inorganic fertilizers in agriculture cultivation system causes many disadventages, such as increase cost production, reduce farmerÃ¢â¬â¢s income and soil fertility, and harm our environment. Therefore, it is needed to find out raw materials for development of organic biostimulant and biofertilizer inducing essential element absorption, growth and yield of plants, which are adaptive to our environment as well. Previous researchres reported that seaweed contained plant growth hormones and essential elements in liquid and solid extracts respectively. This article reports effect of solid and liquid extracts of Sargassum cristafolium on growth and yield of rice plants. The extracts were extracted according to modified procedure.. Solid extract (350 gr) of Sargassum cristafolium was mixed with soil (6650 gr) to become 7 kg soil media. Moreover, liquid extract (10%) of Sargassum cristafolium was sprayed to rice plants once a week during vegetative growth. The results shown that addition of 350 gr of solid extract to soil media increased growth (plant high, tiller number, shoot dry weight and root dry weight) and yield (penicle number and grain weight per plants) significantly compared with those of plants which were not supplied with solid extract. However, spraying liquid extract of Sargassum cristafolium did not affet significantly growth and yield of rice plants, even small change happen in growth and yield parameters of the rice plants supplied with solid extract. This indicates that solid extract is a potential source for development of biofertilizer which is adaptive to our environment to support sustainable agriculture system.
Influence of inclusions on bending fatigue strength coefficient the medium carbon steel melted in an electric furnace
Authors: Lipiński Tomasz , Wach Anna
Published: October 2020

The parameters of high-grade steel are influenced by a combination of factors, including chemical composition and production technology. The impurity content is also a key determinant of the quality of high-grade steel. Inclusions may also play an important role, subject to their type and shape. Inclusions may increase the strength of steel by inhibiting the development of micro-cracks. The analyzed material was one grade of medium-carbon structural steel. The study was performed on 6 heats produced in an industrial plant in 140 ton electric furnaces. The experimental variants were compared in view of the five heat treatment options. The results were presented to account for the correlations between the fatigue strength coefficient during rotary bending, the diameter of and spacing between impurities. The relationship between the fatigue strength and hardness of high-grade steel vs. the quotient of the diameter of impurities and the spacing between impurities was determined. The proposed equations contribute to the existing knowledge base of practices impact of impurities with various diameters and spacing between non-metallic inclusion on fatigue strength.
CLOSING KNOWLEDGE GAPS AND TECHNOLOGICAL BOTTLENECKS IN HYDROGEN SAFETY: A SNAPSHOT OF RECENT ACTIVITIES AT ULSTER UNIVERSITY
Authors:   Hydrogen Safety Engineering and Research Centre (HySAFER), Ulster University, MOLKOV V.
Published: October 2020

The paper presents the progress in hydrogen safety research at HySAFER Centre of Ulster University. It includes results of two research studies performed in 2019. The first study is on the leak-no-burst (LNB) safety technology for explosion free in a fire composite tanks for high-pressure gaseous hydrogen storage. The second study is on the validation of Ulster's models and safety engineering tools against large-scale experiment on hydrogen jet flame from high-pressure hydrogen pipeline.
ВЛИЯНИЕ УСЛОВИЙ ТЕПЛООБМЕНА И ХИМИЧЕСКОЙ КИНЕТИКИ НА СТРУКТУРУ ТЕЧЕНИЯ В МОДЕЛЬНОЙ КАМЕРЕ СГОРАНИЯ ONERA LAPCAT II
Authors:   Центральный аэрогидродинамический институт (ЦАГИ), ВЛАСЕНКО В. В. ,   Московский физико-технический институт (МФТИ), ЛЮ ВЭНЬЧАО , МОЛЕВ С.С. ,   Центральный аэрогидродинамический институт (ЦАГИ), САБЕЛЬНИКОВ В.А. ,   Центральный аэрогидродинамический институт (ЦАГИ),   Французская аэрокосмическая лаборатория (ONERA)
Published: October 2020

Описаны результаты начального этапа численного моделирования эксперимента ONERA LAPCAT II по горению водорода в модельной высокоскоростной камере сгорания. Расчеты проводились с использованием двух моделей химической кинетики. Описано моделирование течения в огневом подогревателе для получения граничного условия на входе в камеру сгорания. Дан физический анализ полученной в расчетах структуры течения в модельной камере. Исследовано влияние теплообмена на стенках канала. Результаты расчетов сопоставлены с экспериментальными и расчетными данными ONERA. Достигнуто хорошее согласование расчетов ЦАГИ и ONERA при использовании близких математических моделей течения. Те и другие расчеты сильно расходятся с экспериментом. Различные причины такого расхождения будут исследованы в последующих расчетах ЦАГИ.
ЧИСЛЕННОЕ МОДЕЛИРОВАНИЕ ВЗАИМОДЕЙСТВИЯ ПРОХОДЯЩЕЙ УДАРНОЙ ВОЛНЫ СО СЛОЕМ ЧАСТИЦ МЕТОДОМ ДЕКАРТОВЫХ СЕТОК
Authors:   Институт автоматизации проектирования Российской академии наук, СИДОРЕНКО Д.А. , УТКИН П.С. ,   Институт автоматизации проектирования Российской академии наук
Published: October 2020

Представлены результаты прямого численного моделирования задачи о взаимодействии скользящей ударной волны (УВ) со слоем подвижных и взаимодействующих частиц на непроницаемой поверхности. Математическая модель основана на двумерных уравнениях Эйлера, которые решаются в области с изменяющейся границей методом декартовых сеток. При описании движения цилиндрических частиц учитываются силы и моменты сил давления газа, а также контактные силы, возникающие при взаимодействии частиц. Для описания столкновений частиц используется стереомеханическая теория удара. Постановка задачи близка рассмотренной в работе Косински и Хоффмана (2005). В прямом моделировании получены эффекты опускания границы слоя частиц за УВ, деформации фронта падающей УВ, а также ее преломления и переотражения в слое, подъема частиц. Получена динамика изменения угловой скорости вращения частиц в количественном выражении, что может быть использовано для анализа влияния силы Магнуса на процесс подъема частиц за УВ.
СТВОРЕННЯ ПАРАМЕТРИЧНОЇ МОДЕЛІ ПОВЕРХНІ ТРИКОТАЖУ ПЕРЕПЛЕТЕННЯ ЛАСТИК 2x2
Authors: Єліна Т. В. , Галавська Л. Є. , Манойленко О. П.
Published: October 2020

This study aims to develop an algorithm for constructing surface models (macro-models) of rib knitted structures, for three-dimensional modeling of tensile deformations in coursewise direction and predicting the physical and mechanical characteristics of knitted fabrics and products. During the research, methods of theoretical analysis, spline theory, computer graphics, programming tools have been used. As a result of the research, it was found that for modeling of some physical and mechanical characteristics of knitted rib structures in a deformed state, it is advisable to use geometric models that reproduce the geometry of the knitted fabric surface with high accuracy, but do not have detailed structure at the level of fibers and threads. If necessary, the values of air permeability, thermal conductivity and others porosity for such models can be taken into account under the form of appropriate indexes. At the same time, to calculate the coefficients of porosity and air permeability, one can use both experimental data and 3D models with a higher detailed structure of the textile material (meso-model). In the course of research a set of geometrical characteristics of samples of rib knits patterns is formed. Samples of 2x2 rib knits of PAN yarn of 31х2 tex have been made with a flat bed knitting machine of 10th gauge. The samples were suspended in the clamps of the relaxometer type "rack" and loaded with weights weighing from 20 to 120 g with an interval of 20 g. By means of the camera, the geometrical characteristics of the knitted surface in dry-relaxed state and in 6 discrete tensile states were recorded and determined. According to the obtained data, parametric 3D models of the knitted surface were built. An algorithm for constructing a macromodel of knitted rib 2x2 structure in the process of stretching in the coursewise direction, taking into account the peculiarities of the situational change in the geometry of the thread within the report has been developed. Three-dimensional parametric models of knitted surface (macro-models) of knitted 2x2 rib structures in the Autodesk Inventor environment have been created.
The genus Camelina (Cruciferae) in Mongolia and China reviewed on the basis of herbarium materials from the Institute of General and Experimental Biology of the ASM (UBA) and the Komarov Botanical Institute (LE)
Authors: Dorofeyev V. I. , Enkhmaa U.
Published: October 2020

Herbarium collections of the genus Camelina preserved at the Institute of General and Experimental Biology of the Academy of Sciences of Mongolia (UBA) and the Komarov Botanical Institute of the Russian Academy of Sciences (LE) were studied. The collections of these Herbaria contain materials of 3 species from Mongolia (C. caucasica (Sinsk.) Vass., C. sativa (L.) Crantz, C. sylvestris Wallr.) and 4 from China (C. sativa, C. linicola Schimp. et Spenn., C. microcarpa Andrz., C. sylvestris).
Una espina en un pajar: espina de pescado alojada en la tiroides
Authors: Pulido Segura Jean Andre , Moreno Torres Andrey , Sanchez Buitrago Diego Alejandro
Published: October 2020

Introducción. La ingestión accidental de cuerpos extraños como espinas de pescado es muy poco frecuente; en ocasiones, pueden alojarse en el esófago y es posible su migración extraluminal. Este accidente se presenta principalmente en países asiáticos por el gran consulo de pescado. La migración extraluminal de una espina de pescado desde el esófago a la glándula tiroides es aún más infrecuente, con pocos reportes en la literatura.

Objetivo. Presentar nuestra experiencia en el diagnóstico y manejo quirúrgico de un paciente con un cuerpo extraño (espina de pescado) alojado en la glándula tiroides y, asimismo, hacer una revisión de la literatura científica.

Caso clínico. Se presenta una paciente de 53 años, sin antecedentes de importancia y con un cuadro clínico de tres meses de evolución consistente en odinofagia posterior a la ingestión accidental de una espina de pescado. En la ecografía practicada en otra institución se observó un cuerpo extraño alojado en el lóbulo tiroideo izquierdo en relación con la musculatura del esófago. En la tomografía de cabeza y cuello se apreciaba una imagen hiperdensa lineal de 2,6 cm de longitud en la misma localización. En la exploración quirúrgica se encontró tejido fibrótico en la región posterior del lóbulo tiroideo izquierdo y se procedió a practicar una tiroidectomía subtotal izquierda. La evolución posoperatoria fue adecuada.

Conclusiones. La migración extraluminal de cuerpos extraños en el tubo digestivo es factible, sobre todo la de las espinas de pescado por su morfología. La tomografía es la herramienta diagnóstica más confiable para detectar cuerpos extraños alojados en la glándula tiroides. Es necesario conocer las posibles complicaciones y, asimismo, optimizar las posibles intervenciones, pues de eso depende el pronóstico clínico del paciente.
Comunicación en Tiempos de COVID, uso efectivo de las señas visuales militares modificadas en momentos quirúrgicos, solución a un problema.
Authors: Sánchez-Hernández Nicolás Daniel , Cabrera-Vargas Luis Felipe , Villarreal-Viana Ricardo Adolfo
Published: October 2020

La  pandemia por el nuevo coronavirus SARS-CoV-2  / COVID 19 ha causado gran impacto tanto en los diferentes espacios hospitalarios como en los no hospitalarios, ocasionando gran número de muertes dado a su gran capacidad de diseminación. Esta patología nos ha llevado a implementar constantes estrategias de cambio con el fin de proteger la integridad del personal médico y de los pacientes. Es por esto que guiados por las grandes asociaciones como World Health Organization, American College of Surgeons, Centers for Disease Control and Prevention, y Asociación Colombiana de Cirugía, se han planteado una serie de protocolos para el buen uso de elementos de protección personal, lo cual en los diferentes momentos quirúrgicos hacen difícil la comunicación asertiva. Dado a lo anteriormente expuesto queremos presentar el uso de las señas visuales militares modificadas como la solución a un problema en procedimientos quirúrgicos en tiempos  de COVID.
La incertidumbre en la apertura de los servicios de cirugía ambulatoria en Colombia
Authors: Díaz-Castrillón Carlos  E.
Published: October 2020

Recibimos con grata satisfacción el esfuerzo de la Asociación Colombiana de Cirugía para estandarizar las pautas de manejo en los servicios quirúrgicos durante la pandemia de COVID-19. Su participación en los comunicados de las sociedades científicas, la promoción de la educación continuada por medios digitales y la creación de una edición especial en esta revista para condensar las contribuciones desde varias partes de Colombia sobre el tema 1, son muestra del liderazgo y la capacidad de resiliencia de los cirujanos en momentos de crisis.
Mortality prediction of ischemic stroke patients without thrombectomy by blood total antioxidant capacity
Authors: Lorente Leonardo , Martín María M. , González-Rivero Agustín F. , Pérez-Cejas Antonia , Abreu-González Pedro , Sabatel Rafael , Ramos-Gómez Luis , Argueso Mónica , Solé-Violán Jordi , Cáceres Juan J. , Jiménez Alejandro , García-Marín Victor
Published: October 2020

It has been previously established that total antioxidant capacity concentrations of blood on the first day of ischemic stroke could predict mortality. Therefore, our study objective was to determine whether total antioxidant capacity concentrations in the blood during the first week of a cerebral infarction could help predict mortality. We included severe and malignant middle cerebral artery infarction patients (affecting 50% or more of the territory in computed tomography and a score of nine or fewer points in the Glasgow Coma Scale). Serum total antioxidant capacity concentrations were determined on days first, fourth, and eighth of the diagnosis of a malignant middle cerebral artery infarction. Higher serum total antioxidant capacity concentrations at first (P< 0.001), fourth (P< 0.001), and eighth (P = 0.003) day were found in non-surviving patients than in surviving ones. Serum total antioxidant capacity concentrations on first, fourth and eighth day of malignant middle cerebral artery infarction had an area under curve (95% Confidence Intervals) for 30-day mortality prediction of 0.86 (0.75-0.93; P<0.001), 0.87 (0.74-0.95; P< 0.001) and 0.79 (0.64-0.90; P = 0.004)), respectively. Thus, the potential use of serum total antioxidant capacity concentrations at any time during the first 7 days of a severe malignant middle cerebral artery infarction without thrombectomy to predict mortality was the main novel finding of our study.
Muramyl dipeptide promotes Aβ1-42 oligomer production via the nod2/p-p38 mapk/bace1 signaling pathway in the sh-sy5y cells
Authors: Chen Yan-Jie , Chan Yuan-Jin , Chen Wen-Jing , Li Ya-Ming , Zhang Chun-Yan
Published: October 2020

The relationship between chronic bacterial colonization in the brain and Alzheimer’s disease is attracting extensive attention. Recent studies indicated that the components of bacterial biofilm drive the amyloid-β production. Muramyl dipeptide, the minimal bioactive peptidoglycan motif common to all bacteria, contributes to the development of many central inflammatory and neurodegenerative disorders. However, the involvement of Muramyl dipeptide in amyloid-β production is not completely defined. In our present study, wild type mice received an intracerebroventricular injection of normal saline or Muramyl dipeptide. Data showed that the production of Aβ1-42 oligomers was significantly increased after Muramyl dipeptide injection in the wild type mice or incubation of the SH-SY5Y cells with Muramyl dipeptide. Moreover, the action of Muramyl dipeptide was dose- and time-dependent. The above results suggested a possibility that the Muramyl dipeptide -induced Aβ1-42 oligomer production might be related to the NOD2/p-p38 MAPK/BACE1 pathway. To confirm this, the SH-SY5Y cells were transfected with siRNA NOD2. Data showed that the transfected SH-SY5Y cells exhibited decreased expression of Aβ1-42 oligomer, NOD2, p-p38 MAPK, and BACE1 after treatment with Muramyl dipeptide. Finally, SH-SY5Y cells were pretreated with SB203580, an inhibitor of the p-38-MAPK pathway. The results indicated that these pretreated SH-SY5Y cells exhibited decreased expression of Aβ1-42 oligomer, p-p38 MAPK, and BACE1 after treatment with Muramyl dipeptide. In conclusion, these results suggested that Muramyl dipeptide was the trigger factor for Aβ1-42 oligomer production, which probably acts via the NOD2/p-p38 MAPK/BACE1 signaling pathway.
Relationship between recovery of motor function and neuropsychological functioning in cerebral infarction patients: the importance of social functioning in motor recovery
Authors: Chang Min Cheol , Park Sung-Won , Lee Byung-Joo , Park Donghwi
Published: October 2020

Impaired motor function is a common disabling sequela after stroke. It is closely associated with the patient’s quality of life and independence. Neuropsychological dysfunctions also frequently occur in stroke patients. In this paper, we evaluate the relationship between the recovery of motor function and neuropsychological functions, including cognition, language, emotion, behavior, personality, and social interaction, to provide appropriate and effective therapy for stroke patients. Motor function, neuropsychological status, social functioning, as well as emotional aspects such as depression and anxiety symptoms, were initially evaluated one month after cerebral infarction onset. The evaluations were repeated three months after the onset. Motor function was assessed with the Modified Barthel Index. The neuropsychological status was evaluated using the Mini-Mental State Examination, Global Deterioration Scale, digit span test, Korean-Boston Naming Test, Vineland Social Maturity Scale, Neuropsychiatric Inventory, Beck’s Depression Inventory, and Beck Anxiety Inventory.In the results,theModified Barthel Index, Mini-Mental State Examination, Global Deterioration Scale, digit span test, and Vineland Social Maturity Scale were significantly different between the two-time points (P < 0.05). Initial Social Maturity Scale Social Age and Social Maturity Scale Social Quotient categories of the Vineland Social Maturity Scale and Mini-Mental State Examination scores were significantly correlated with Modified Barthel Index improvement (P < 0.05). The amount of change in the Social Maturity Scale Social Age and Social Maturity Scale Social Quotient scores was significantly correlated with Modified Barthel Index improvement (P < 0.05). In multiple linear regression analysis, only the initial Social Maturity Scale Social Quotient score and the amount of score change in Social Maturity Scale Social Quotient showed a significant correlation with Modified Barthel Index improvement (P < 0.05).Social function and interaction are important in motor recovery of ischemic stroke patients.
[18F] FDOPA PET may confirm the clinical diagnosis of Parkinson's disease by imaging the nigro-striatal pathway and the sympathetic cardiac innervation: Proof-of-concept study
Authors: Kuten Jonathan , Linevitz Adi , Lerman Hedva , Freedman Nanette , Kestenbaum Meir , Shiner Tamara , Giladi Nir , Even-Sapir Einat
Published: October 2020

Autonomic involvement, including cardiac denervation, may precede the motor symptoms of Parkinson’s disease by several years. L-3,4-dihydroxy-6-[18F] fluoro-phenylalanine is a positron emitter and a true analog of L-dopa, used in clinical practice to assess striatal dopaminergic integrity. The present study aimed to assess the feasibility of evaluating cardiac sympathetic denervation in Parkinson’s disease patients using L-3,4-dihydroxy-6-[18F] fluoro-phenylalanine positron emission tomography/computed tomography. Patients referred for an L-3,4-dihydroxy-6-[18F] fluoro-phenylalanine positron emission tomography/computed-tomography between July 2015 and May 2017 to evaluate striatal presynaptic dopaminergic integrity underwent a heart positron emission tomography scan following a brain positron emission tomography scan. L-3,4-dihydroxy-6-[18F] fluoro-phenylalanine uptake in the left ventricle was quantified using CarimasT⁢M software and compared between patients with and without Parkinson’s disease. The area under the receiver operating characteristic curve was used to evaluate the ability of the left ventricular mean standardized uptake value to discriminate between patients with Parkinson’s disease and those with other extrapyramidal syndromes. Seventy-six patients were included, of whom 52 were diagnosed with Parkinson’s disease. The mean L-3,4-dihydroxy-6-[18F] fluoro-phenylalanine left ventricular mean standardized uptake value was lower in the Parkinson’s disease patients compared to the non- Parkinson’s disease patients (1.08 ± 0.21 vs. 1.24 ± 0.32, P = 0.015). The left ventricular mean standardized uptake value was able to discriminate between Parkinson’s disease and non- Parkinson’s disease patients (the area under the receiver operating characteristic curve = 0.641, P = 0.049). In conclusion, quantification of cardiac L-3,4-dihydroxy-6-[18F] fluoro-phenylalanine uptake may be able to differentiate between patients with and without Parkinson’s disease. Validation of this finding in more substantial, prospective trials are warranted.
Clinical interpretations of the effectiveness of changes in body position during aerobic fitness after neurologic injury
Authors: Izan Nur Fariza , Salleh Sheikh Hussain , Ting Chee-Ming , Noman Fuad , Sh-Hussain Hadrina , Poznanski Roman R. , Latif ‪Ahmad Zubaidi Abdul
Published: October 2020

The purpose is to estimate the effectiveness of electrocardiograms during resting and active participation by the differentiation between the electrical activity of the heart while standing and sitting in a resting state. The concern is to identify the electrocardiogram parameters that did not show significant changes within these positions. The electrocardiogram parameters can be considered to be a standard marker for medically compromised patients. The electrocardiogram is recorded in the standing and sitting positions focusing on healthy participants using standard electrode placement of lead-I. Combined lead-I patterns (camel-hump or ST-segment prolongation) are usually seen in neurologic injury or hypothermia patients. The pairwise comparisons of a year data are about 454,400 cycles of sitting and 493,470 cycles of standing data. Thus, it is essential to quantify the nature and magnitude of changes seen in the electrocardiogram with a change of posture from sitting to standing in a healthy individual. This makes the findings of electrocardiogram analysis in this paper interesting in which some parameters (i.e., camel-hump patterns in lead-I) are helpful for clinical interpretations and could be suggestive of neurologic injury.
Early tracheostomy is associated with better prognosis in patients with brainstem hemorrhage
Authors: Ding Wei-Long , Xiang Yong-Sheng , Liao Jian-Cheng , Wang Shi-Yong , Wang Xiang-Yu
Published: October 2020

Brainstem hemorrhage is presumed to be invariably associated with a poor prognosis in people with spontaneous hypertensive cerebral hemorrhage. The optimal timing of tracheostomy placement in brainstem hemorrhage patients, who generally require endotracheal intubation for airway protection, remains uncertain. Our research aim was to analyze the impact of early tracheostomy versus late tracheostomy on brainstem hemorrhage patients related outcomes and prognostic factors at 30 days. We identified early tracheostomy and how it could benefit the patients with brainstem hemorrhage and ameliorate the predictors of functional recovery at 30 days. Data on 136 patients with brainstem hemorrhage and Glasgow Coma Scale score ≤ 8, were retrospectively collected from 2012 to 2019. Patients were divided into the early tracheostomy group and the late tracheostomy group. Patients in the early tracheostomy group had a significantly lower neurosurgical intensive care unit stay (both overall and survival) compared with the late tracheostomy group (15.6 days vs. 19.0 days, P = 0.041, overall and 14.5 vs. 19.5 days, P = 0.023, survival). Also, the good outcomes (modified Rankin Score ≤ 3) were higher in the early tracheostomy group (P = 0.036). Multivariate analysis demonstrated that less hemorrhagic volume, high Glasgow Coma Scale score on admission, young age, and early tracheostomy were significantly associated with a better 30-day functional outcome. In conclusion, an early tracheostomy in patients with brainstem hemorrhage can reduce neurosurgical intensive care unit stay, and in addition to improvements in prognosis at 30 days.
The effects of erythropoietin on neurogenesis after ischemic stroke
Authors: Zhang Si-Jia , Luo Yu-Min , Wang Rong-Liang
Published: October 2020

Erythropoietin has been researched for its neuroprotective effects in ischemic stroke for over 30 years. Although erythropoietin can cause side effects that need to be controlled, it has been suggested to be effective in enhancing the prognosis of patients who are out of the therapeutic time window and have not received recombinant tissue plasminogen activator therapy. Studies on the mechanism of the function of erythropoietin have shown that it has various protective effects in ischemic brain injury after stroke, including promoting neurogenesis. In this review, we discuss the effects of erythropoietin on neurogenesis after ischemic brain injury and provide references for effective treatments for ischemic stroke, which is one of the leading causes of death worldwide.
Cardiac sarcoidosis: diagnosis and management
Authors: Markatis Eleftherios , Afthinos Andreas , Antonakis Emmanouil , Papanikolaou Ilias C
Published: October 2020

Sarcoidosis is a chronic inflammatory disease of unknown etiology characterized by multi-organ involvement. End-organ disease consists of granulomatous inflammation, which if left untreated or not resolved spontaneously, leads to permanent fibrosis and end-organ dysfunction. Cardiac involvement and fibrosis in sarcoidosis occur in 5-10% of cases and is becoming increasingly diagnosed. This is due to increased clinical awareness among clinicians and new diagnostic modalities, since magnetic resonance imaging and positron-emission tomography are emerging as “gold standard” tools replacing endomyocardial biopsy. Despite this progress, isolated cardiac sarcoidosis is difficult to differentiate from other causes of arrhythmogenic cardiomyopathy. Cardiac fibrosis leads to congestive heart failure, arrhythmias and sudden cardiac death. Immunosuppressives (mostly corticosteroids) are used for the treatment of cardiac sarcoidosis. Implantable devices like a cardioverter-defibrillator may be warranted in order to prevent sudden cardiac death. In this article current trends in the pathophysiology, diagnosis and management of cardiac sarcoidosis will be reviewed focusing on published research and latest guidelines. Lastly, a management algorithm is proposed.
Impact of human immunodeficiency virus (HIV) infection in patients undergoing cardiac surgery: a systematic review
Authors: Dominici Carmelo , Chello Massimo
Published: October 2020

The clinical status and prognosis of patients with human immunodeficiency virus (HIV) infection has dramatically changed in the recent years. Cardiovascular diseases can be related to combined antiretroviral therapy and to the aging of HIV-positive population, resulting in significant mortality and morbidity in those patients. It is crucial to understand whether the HIV-status affects the indications and outcomes of cardiac surgery. A literature search was conducted through electronic databases up to 15 May 2020 following PRISMA guidelines. Variables (i.e. patients characteristics) and endpoints (i.e. postoperative complications) were considered as defined in the original publications. All paper describing post-operative outcomes after cardiac surgery were included. Methodological quality of all included studies was assessed using the Newcastle-Ottawa Scale, the Cochrane Risk of Bias tool and the US Preventive Services Task Force grade. A total of eight studies were included in this systematic review; five studies discussed the outcomes of patients with HIV infection, while three studies compared results based on HIV status. All evidences derived from retrospective observational studies with high variability and poor-to-fair quality. Most patients underwent surgical myocardial revascularization. HIV status is not associated with differences in operative mortality (P = 0.32), postoperative mediastinitis (P = 0.30) or pulmonary infective complications (P = 0.67). Cardiac surgery can be considered safe in HIV-positive patients, and HIV status alone should not be considered as a contraindication for cardiac surgery and should not be considered a risk factor for postoperative mortality or perioperative complications. Further studies are required for patients with AIDS.
Usefulness of machine learning in COVID-19 for the detection and prognosis of cardiovascular complications
Authors: Zimmerman Allison , Kalra Dinesh
Published: October 2020

Since January 2020, coronavirus disease 2019 (COVID-19) has rapidly become a global concern, and its cardiovascular manifestations have highlighted the need for fast, sensitive and specific tools for early identification and risk stratification. Machine learning is a software solution with the ability to analyze large amounts of data and make predictions without prior programming. When faced with new problems with unique challenges as evident in the COVID-19 pandemic, machine learning can offer solutions that are not apparent on the surface by sifting quickly through massive quantities of data and making associations that may have been missed. Artificial intelligence is a broad term that encompasses different tools, including various types of machine learning and deep learning. Here, we review several cardiovascular applications of machine learning and artificial intelligence and their potential applications to cardiovascular diagnosis, prognosis, and therapy in COVID-19 infection.
Critical complications of COVID-19: A descriptive meta-analysis study
Authors: Vakili Kimia , Fathi Mobina , Pezeshgi Aiyoub , Mohamadkhani Ashraf , Hajiesmaeili Mohammadreza , Rezaei-Tavirani Mostafa , Sayehmiri Fatemeh
Published: October 2020

The coronavirus disease 2019 (COVID-19) is a novel coronavirus infection that has rapidly spread worldwide, causing a pandemic. The main objective of this meta-analysis was to evaluate the prevalence of the most common symptoms and complications of COVID-19. All relevant studies on the clinical complications of COVID-19 have been identified by searching two web databases (i.e., PubMed and Scopus). Afterward, the relevant data were extracted from the selected studies, and then analyzed by the STATA (Version 14) random-effects model. The 30 studies selected for our meta-analysis covered 6,389 infected patients. The prevalence rates of the most common symptoms were as follows: fever: 84.30% (95% CI: 77.13-90.37; I2 = 97.74%), cough: 63.01% (95% CI: 57.63-68.23; I2 = 93.73%), dyspnea: 37.16% (95% CI: 27.31-47.57%; I2 = 98.32%), fatigue: 34.22% (95% CI: 26.29-42.62; I2 = 97.29%), and diarrhea: 11.47% (95% CI: 6.96-16.87; I2 = 95.58%). Moreover, the most prevalent complications were found to be acute respiratory distress syndrome (ARDS) with 33.15% (95% CI: 23.35-43.73; I2 = 98.56%), arrhythmia with 16.64% (95% CI: 9.34-25.5; I2 = 92.29%), acute cardiac injury with 15.68% (95% CI: 11.1-20.97; I2 = 92.45%), heart failure with 11.50% (95% CI: 3.45-22.83; I2 = 89.48%), and acute kidney injury (AKI) with 9.87% (95% CI: 6.18-14.25; I2 = 95.64%). In this study, we assessed the prevalence of the main clinical complications of COVID-19, and found that following respiratory complications, cardiac and renal complications are the most common clinical complications of COVID-19.
Vitamin D deficiency in association with endothelial dysfunction: Implications for patients with COVID-19
Authors: Zhang Jun , McCullough Peter A. , Tecson Kristen M.
Published: October 2020

There is emerging evidence to suggest that vitamin D deficiency is associated with adverse outcomes in COVID-19 patients. Conversely, vitamin D supplementation protects against an initial alveolar diffuse damage of COVID-19 becoming progressively worse. The mechanisms by which vitamin D deficiency exacerbates COVID-19 pneumonia remain poorly understood. In this review we describe the rationale of the putative role of endothelial dysfunction in this event. Herein, we will briefly review (1) anti-inflammatory and anti-thrombotic effects of vitamin D, (2) vitamin D receptor and vitamin D receptor ligand, (3) protective role of vitamin D against endothelial dysfunction, (4) risk of vitamin D deficiency, (5) vitamin D deficiency in association with endothelial dysfunction, (6) the characteristics of vitamin D relevant to COVID-19, (7) the role of vitamin D on innate and adaptive response, (8) biomarkers of endothelial cell activation contributing to cytokine storm, and (9) the bidirectional relationship between inflammation and homeostasis. Finally, we hypothesize that endothelial dysfunction relevant to vitamin D deficiency results from decreased binding of the vitamin D receptor with its ligand on the vascular endothelium and that it may be immune-mediated via increased interferon 1 α. A possible sequence of events may be described as (1) angiotensin II converting enzyme-related initial endothelial injury followed by vitamin D receptor-related endothelial dysfunction, (2) endothelial lesions deteriorating to endothelialitis, coagulopathy and thrombosis, and (3) vascular damage exacerbating pulmonary pathology and making patients with vitamin D deficiency vulnerable to death.
Cardiovascular effects of waterpipe smoking: a systematic review and meta-analysis
Authors: Al Ali Radwan , Vukadinović Davor , Maziak Wasim , Katmeh Lama , Schwarz Viktoria , Mahfoud Felix , Laufs Ulrich , Böhm Michael
Published: October 2020

Waterpipe smoking has developed into a major and rapidly growing global tobacco epidemic affecting more than 100 million people worldwide. This study identifies and analyzes comprehensively all available data on the cardiovascular effects of waterpipe smoking. Databases PubMed, EMBASE, Web of Science, and the Cochrane Library were searched for studies published until December 2019 assessing cardiovascular effects of waterpipe smoking. We included experimental, cohort, cross-sectional and case-control studies and excluded systematic reviews, case reports/series and qualitative studies. Studies not conducted in humans or not distinguishing waterpipe smoking from other forms of smoking were also excluded. A total of 42 studies with 46 cardiovascular parameters were eligible for analysis. The meta-analysis included 31 studies with 38,037 individuals. Results showed that one waterpipe smoking session leads to immediate increases in heart rate and blood pressure (P < 0.001). Compared to non-smokers, waterpipe smokers had significantly lower high-density lipoprotein levels (P < 0.001), higher levels of low-density lipoprotein (P = 0.04), triglyceride (P < 0.001) and fasting blood glucose (P = 0.03) and higher heart rate (P = 0.04) with a tendency to have higher blood pressure. Mean heart rate, blood pressure and lipids levels did not differ between waterpipe and cigarette smokers, except for total cholesterol, being higher among waterpipe smokers (P < 0.001). Current level of evidence suggests that waterpipe smoking is associated with substantial adverse effects on cardiovascular system, which seem to be similar to those of cigarette smoking. Longitudinal studies are required to scrutinize the magnitude of these effects.
Positive chronotropic effects of theophylline and cilostazol in patients with symptomatic sick sinus syndrome who have declined permanent pacing
Authors: Jin In Tae , Yoon Namsik , Jeong Hyung Ki , Lee Ki Hong , Park Hyung Wook , Cho Jeong Gwan
Published: October 2020

Pacemakers are more commonly recommended than theophylline for sick sinus syndrome (SSS) treatment. The positive effects of cilostazol on bradyarrhythmias also have been reported. However, no comparison of cilostazol and theophylline has been previously reported found. We retrospectively enrolled SSS patients, who refused a pacemaker implantation. Theophylline or cilostazol was administered, and the heart rate (HR) was evaluated in 4-8 weeks using a digital sphygmomanometer and the electrocardiogram (ECG). A 200-400 mg of theophylline or 100-200 mg of cilostazol were administered per day in 50 and 30 patients, respectively. The baseline HR was 54.8 ± 13.5 beats per minute (bpm) on using sphygmomanometry and 51.9 ± 11.8 bpm using the ECG. In the theophylline group, the HR increased by 12.0 ± 16.3 bpm by sphygmomanometry (P < 0.001) and 8.4 ± 12.0 bpm by the ECG (P < 0.001). In the cilostazol group, the HR increased by 16.8 ± 13.9 bpm by sphygmomanometry (P < 0.001) and 12.4 ± 13.4 bpm using the ECG (P < 0.001). In 15 of the 50 theophylline patients, the medication was switched to cilostazol. The HR increased from 61.4 ± 13.8 bpm to 64.0 ± 12.6 bpm (P = 0.338). Symptoms such as dyspnea, chest discomfort, dizziness, and syncope significantly improved after the administration of the medications. There were no significant differences in the improvement in the symptoms except for dizziness between the two agents. Cilostazol was as effective as theophylline for increasing the HR in SSS patients.
Ruang Adat di Kampung Dukuh Dalam sebagai Bentuk Kehidupan Spiritual
Authors: Sriwardani Nani , Dienaputra Reiza D , Machdalena Susi , Kartika N
Published: October 2020

Masyarakat Adat Sunda tersebar di daerah di Jawa Barat, beberapa kampung bersifat tertutup dengan mempertahankan adat istiadat kebiasaan secara turun termurun dan sebagian juga ada yang mengalami penyesuain pada nilai-nilai kebudayaannya. Kampung Dukuh yang terletak di Desa Cijambe, Kecamatan Cikelet, Kabupaten Garut, merupakan salah satu kampung yang memiliki keduanya. Kampung tersebut memberi batas antara â€œdalamâ€ dan â€œluarâ€. Pemisahan â€œdalamâ€ dan â€œluarâ€ ini memiliki perbedaan dalam menciptakan kesakralan ruang dan kondisi manusia yang ada di lingkungan tersebut. Penelitian ini bertujuan memberikan gambaran nilai kehidupan spiritual yang hadir melalui batas ruang lingkup suatu kampung adat. Metode yang digunakan adalah dengan pendekatan deskriptif kualitatif, dengan mengutamakan berbagai data literatur serta survei dilapangan. Hasilnya ditemukan bahwa terdapat batas wilayah atau ruang yang membatasi antara Dukuh Dalam dan Dukuh Luar. Kampung Dukuh mengedepankan akhlaq dalam sistem kehidupannya dan di Kampung Dukuh Dalam aturan tawadhu, sederhana, dan harmonis dijalankan sepernuhnya sampai kepada gaya hidup dan lingkungannya. Pegangan hidup masyarakat Kampung Dukuh Dalam berpedoman pada ajaran agama Islam yang berlandaskan Al Quran dan Hadist. Hasil dan kajian ini diharapkan dapat menjadi wawasan pengetahuan perihal Kampung Dukuh Dalam dan wilayah serta ruang yang menaunginya.
Faktor Ideasi dalam Proses Kreasi Seniman Lukis Jelekong
Authors: Shabiriani Uzda Nabila , Junaidy Deny Willy , Setiawan Pindi
Published: October 2020

Alih keterampilan yang dilakukan secara turun-temurun dalam komunitas pelukis Jelekong yang tidak memiliki latar belakang pendidikan seni formal telah berlangsung selama 50 tahun dan menghasilkan karakter khas dari lukisan Jelekong yang secara konsisten dipraktekkan dalam memproduksi karya lukis. Tujuan penelitian ini adalah untuk mengetahui faktor ideasi seniman lukis Jelekong yang tidak memiliki latar belakang pendidikan seni formal agar membangun pemahaman mengenai proses kreasi pada konteks pewarisan keahlian melukis secara turun-temurun. Penelitian ini menganalisis proses kreasi pada ideasi tahap awal dengan metode verbal report, melalui analisis jaringan konsep asosiatif dari pengalaman subjek saat menggambar sketsa, image analysis dan analisis faktor. Dari hasil analisis, 10 pelukis Jelekong yang diteliti dalam pikirannya saat proses menggambar sketsa mengarah kepada harmoni yang diindikasikan melalui jarak rumah yang berdekatan, penempatan objek yang umumnya berjumlah dua di sisi kanan dan kiri, perbedaan warna objek jauh dan dekat, alam yang ideal dengan adanya awan, bentuk figuratif dan benda alam lainnya, perbedaan garis untuk memberikan tekstur, perbedaan profesi, perbedaan aktifitas, serta komposisi yang seimbang. Ketika menggambar sketsa, pelukis juga mempertimbangkan ketenangan yang diindikasikan melalui suasana yang sepi dengan tidak adanya unsur alam yang rusak, seperti kekeringan namun suasana yang sejuk, ingatan seniman akan suasana alam yang sejuk dan tenang, serta gambar-gambar dengan ruang yang luas, seperti penggambaran satu rumah dan sangat jarang menggambar banyak makhluk hidup. Faktor ideasi dalam proses kreasi seniman lukis Jelekong cenderung mempraktikkan peniruan atau mencontoh karya yang telah dibuat sebelumnya dan sangat jarang ditemukan unsur kebaruan, sehingga seringkali menemukan harmoni dan ketenangan pada setiap karya.
Laporan Minggu 4
Authors: Nur Akbar
Published: October 2020

Observasi adalah kegiatan praktek pembuatan kripik depan masyarakat
Laporan kegiatan keenam minggu ketiga posko bontonompo
Authors: asmelisari
Published: October 2020

Kuliah Kerja Lapang Plus (KKLP) Merupakan suatu Kegiatan Perkuliahan yang Bersifat intrakurikuler dalam bentuk pengabdian pada masyarakat yang di lakukan oleh mahasiswa dalam jangka waktu tertentu. Oleh karena, sifatnya intrakurikuler sehingga setiap mahasiswa yang akan menyelesaikan studi di perguruan tinggi pada suatu program strata satu (S1) harus mengikuti KKLP.
Tanggung Jawab Gereja Mengatasi Masalah Kemiskinan (Analisis Jurnal)
Authors: Hartantio Eunike Ivana
Published: October 2020

Eunike Ivana Hartantio, Kemiskinan merupakan masalah yang kompleks yang dihadapi oleh semua negara di dunia dan menentukan maju atau tidaknya suatu negara. Pada zaman sekarang gereja sudah melupakan peran dan tanggung jawabnya dalam membela orang-orang miskin dan menjadi alat bagi orang kaya. Gereja seharusnya ikut mengambil peran dalam membela hak orang miskin sebagai bentuk cerminan teladan Yesus Kristus yang tidak menyukai penindasan orang kaya terhadap orang miskin.
Laporan mingguan ke 4
Authors: kasim Sri utami
Published: October 2020

Membuat tempat sampah untuk setiap mesjid di lingkungan tolo timur
Gotong Royong " Jumat Bersih"
Authors: Kaharuddin
Published: October 2020

Jumat Bersih Masjid Babul Jihad Kassi-Kassi
Laporan minggu ke tiga kegiatan lima
Authors: muh.risal
Published: October 2020

Kuliah Kerja Lapang Plus (KKLP) Merupakan suatu Kegiatan Perkuliahan yang Bersifat intrakurikuler dalam bentuk pengabdian pada masyarakat yang di lakukan oleh mahasiswa dalam jangka waktu tertentu. Oleh karena, sifatnya intrakurikuler sehingga setiap mahasiswa yang akan menyelesaikan studi di perguruan tinggi pada suatu program strata satu (S1) harus mengikuti KKLP
DAMPAK MEDIA PEMBELAJARAN ZOOM BAGI MINAT BELAJAR MAHASISWA STT SANGKAKALA
Authors: EDWIN ED DWI
Published: October 2020

Pendidikan adalah indikator penting yang menentukan kemajuan dari perserta didik. Diperlukan kualitas pendidikan yang baik supaya tujuannya yaitu, mencerdaskan perserta didik dapat terlaksana dengan baik. Pendidikan adalah sebuah usaha untuk meningkatkan ilmu pengetahuan yang didapat baik dari lembaga formal maupun informal untuk memperoleh manusia yang berkualitas dan berpengetahuan. Di dalam dunia pendidikan juga terdapat proses pembelajaran. Proses pembelajaran adalah kegiatan yang berproses melalui tahapan perancangan, pelaksanaan, dan evaluasi. Pembelajaran merupakan usaha yang dilakukan untuk menfasilitasi terjadinya proses belajar pada anak didik. Pembelajaran dimaknai pula sebagai interaksi peserta didik dengan pendidik dan sumber belajar dalam suatu lingkungan belajar. Dalam pelaksanaan proses pembelajaran dapat dilaksanakan dengan tatap muka dan virtual (tidak bertatap muka)
Laporan minggu ketiga kegiatan ke 4
Authors: pertiwi
Published: October 2020

Kegiatan bakti sosial lingkungan
Laporan mingguan pertama
Authors: kasim Sri utami
Published: October 2020

Observasi adalah mencari tahu informasi yang ada di dalam lingkungan sekitar.
Physical Effects of Daily Stressors are Psychologically Mediated, Heterogeneous, and Bidirectional
Authors: Goldring Megan
Published: October 2020

Prior research has shown that daily stressors lead to greater psychological distress. A separate body of research links daily stressors to physical symptoms such as backaches and stomach problems. In this paper, we integrate these literatures by positing an interconnected causal system, whereby stressors lead to psychological distress which, in turn, leads to physical symptoms. Further, we suggest that not everyone exhibits the same level of psychological reactivity to daily stressors nor do they somaticize psychological distress in the same way. Instead, between-person heterogeneity is a core feature of the daily stress process. Finally, we assert that causal effects between daily stressors, psychological distress, and physical symptoms can be bidirectional. For example, psychological distress can increase physical symptoms and physical symptoms can also increase psychological distress. Having provided evidence for this integrated causal feedback system, we consider its implications for existing knowledge and highlight critical areas for future study.
Laporan Minggu pertama
Authors: Nur Akbar
Published: October 2020

Melakukan Observasi, Untuk Mengatahui Apa Yang Bisa Di kembangkan.
Formation of residual stresses in austenitic stainless steels by infeed and recess rotary swaging
Authors: Hoche Holger , Jaeger Fabian , Franceschi Alessandro , Oechsner Matthias , Groche Peter
Published: October 2020

The austenitic stainless steels 1.4307 and 1.4404 significantly benefit from cold forming, due to their high work hardening capability. Great potential to improve the component's fatigue properties is expected by optimizing the forming process chain such that specific residual stresses are induced in critical component areas. In this work, an analysis of the formation of residual stresses during rotary swaging is carried out. Through this incremental forming process, high strain hardening and a complex material flow history are induced in the workpieces. Therefore, measuring strategies for the residual stress measurement of cold de-formed austenitic steels by X-Ray diffraction, using the sin2Ψ-method, were developed. Here, especially the 1.4307 is a challenging material due to cold forming induced martensite formation. Despite phase changes, both cold formed materials exhibit anisotropic microstructures as well as coarse grained areas. Moreover, particular notched geometries are produced on the workpieces by rotary swaging. The measuring techniques are further developed for these complex geometries and the residual stresses are investigated.