bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantifying aminoglycoside resistance in extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales clinical isolates: a retrospective cohort study
Authors: Vock Isabelle , Aguilar-Bultet Lisandra , Khanna Nina , Egli Adrian , Wehrle-Wieland Elisabeth , Tamma Pranita D. , Tschudin Sutter Sarah
Published: October 2024

AIMS: Aminoglycoside resistance is frequently detected in extended-spectrum-beta-lactamase (ESBL)-producing Enterobacterales (ESBL-PE), questioning the appropriateness of aminoglycosides as empiric therapy in patients with suspected ESBL-PE infections. Therefore, we aimed to evaluate the frequency of aminoglycoside resistance in patients harbouring ESBL-PE and identify patient-related risk factors associated with aminoglycoside resistance to facilitate early detection of at-risk patients.
METHODS: This retrospective single-centre cohort study included hospitalised patients aged ≥18 years with an ESBL-PE-positive sample between January 2016 and December 2018. Aminoglycoside resistance was defined according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoints for Enterobacterales for the current year of testing.
RESULTS: Five hundred forty-four patients met the eligibility criteria, of which 240 (44.1%) harboured aminoglycoside-resistant ESBL strains. Identification of ESBL-Klebsiella pneumoniae was significantly associated with aminoglycoside resistance (odds ratio [OR] = 2.64, 95% confidence interval [CI] = 1.65–4.21, p <0.001) and an international travel history within the past 12 months was marginally associated with aminoglycoside resistance (OR = 1.51, 95% CI = 0.95–2.42, p = 0.084).
CONCLUSIONS: In a low ESBL endemicity setting, aminoglycoside resistance in patients harbouring ESBL-PE is common, especially ESBL-K. pneumoniae, and needs to be considered in clinicians’ decision-making regarding empiric therapy regimens.
InterSCity: uma plataforma para cidades inteligentes
Authors: Kanashiro Lucas , Costa Fábio M. , Conceição Arlindo Flavio da
Published: October 2024

Este artigo apresenta uma plataforma de software escalável para amparar a integração de recursos e serviços e facilitar o desenvolvimento de aplicações para cidades inteligentes. Serviços fundamentais em uma plataforma como essa são os de gerenciamento e análise de dados.
Processamento de Big Data Urbano
Authors: Braghetto Kelly Rosa , Cordeiro Daniel , Goldman Alfredo
Published: October 2024

Este artigo caracteriza as ferramentas e ambientes computacionais usados no armazenamento e processamento de Big Data urbano. Considerando os grandes volumes de dados gerados em períodos muito curtos de tempo no contexto das Cidades Inteligentes,  o artigo destaca a necessidade de técnicas de armazenamento e processamento adequadas para extrair conhecimento desses grandes volumes de dados com tempo de resposta adequado às diversas aplicações, sistemas e serviços.
Segurança em Internet das Coisas
Authors: Batista Daniel , Kaminski Carlos Alberto , Duarte Otto Carlos Muniz Bandeira
Published: October 2024

Este artigo discute aspectos relacionados à segurança dos dados que trafegam entre os recursos e as aplicações em ambiente de Cidades Inteligentes. O artigo destaca a necessidade de proteger de forma eficiente e escalável uma grande quantidade de dispositivos conectados à Internet de Coisas.
Das südkoreanische Wahlsystem und die Parlamentswahl vom 10. April 2024
Authors: Mosler Hannes B.
Published: October 2024

The parliamentary elections to South Korea’s 22nd National Assembly on April 10, 2024, were a classic mid-term election occurring during the five-year term of conservative President Yoon Suk-yeol, who had assumed office two years earlier . The election results reflected a clear protest vote against the conservative People Power Party (PPP), which was perceived to suffer as a result of its president’s poor government policies . This led to the opposition liberal Democratic Party (DP) securing a clear majority of seats in the National Assembly . The restrictive and exclusive electoral law ensured that the duopoly of these two dominant parties remained virtually untouched and smaller, alternative parties were systematically disadvantaged . Previous attempts, including the most recent electoral law reform, to break up this exclusive party cartel of a hostile symbiosis of conservative and liberal parties have failed . As a result, an ideologically distorted two-party system persists, impeding the development of a sustainable quality of democracy .
Совершенствование занятий по физической культуре со студентами не физкультурных вузов Китая посредством использования игровых методов (на примере баскетбола)
Authors: Су В. , Линь Х. , Кабачкова А. , Сидоренко Т.
Published: October 2024

в статье приводятся результаты диагностического спортивного тестирования, мониторинга физических нагрузок студентов, педагогического эксперимента 846 учащихся китайского нефизкультурного вуза – Даляньского технологического университета. Период проведения экспериментальной работы – 2020-2023 гг. Предварительные результаты мониторинга физических нагрузок студентов и диагностического спортивного тестирования определили необходимость в разработке авторской концепции экспериментальной программы, способствующей увеличению физической активности и эффективности физического воспитания. Содержание экспериментальной программы включало средства и методы спортивной игры – баскетбола в связи с предположением о том, что конкретизация условий двигательной активности студентов с применением игровых методов спорта может способствовать улучшению эмоционального благополучия и параметров физической подготовленности. В соответствии с проведенным исследованием был выявлен положительный результат практического применения авторской экспериментальной программы с включением средств и методов спортивной игры – баскетбола, что обусловлено изменением частоты сердечных сокращений (ЧСС), параметров физической активности студентов в соответствии с выбранными тестами, уровня мотивации и эмоционального благополучия учащихся. Представленная концепция экспериментальной программы физического воспитания студентов может быть включена в учебную программу по физкультуре китайских нефизкультурных вузов.

the article presents the results of diagnostic sports testing, monitoring of students' physical activity, and a pedagogical experiment of 846 students of a Chinese non-physical education university – Dalian University of Technology. The period of experimental work is 2020-2023. Preliminary results of monitoring students' physical activity and diagnostic sports testing determined the need to develop the author's concept of an experimental program that would help increase physical activity and the effectiveness of physical education. The content of the experimental program included the means and methods of a sports game - basketball, in connection with the assumption that specifying the conditions of students' physical activity using game methods of sports can help improve emotional well-being and physical fitness parameters. In accordance with the study, a positive result was revealed from the practical application of the author's experimental program with the inclusion of means and methods of the sports game – basketball, which is due to changes in heart rate (HR), parameters of physical activity of students in accordance with selected tests, level of motivation and emotional well-being of students. The presented concept of an experimental program for physical education of students can be included in the physical education curriculum of Chinese non-physical education universities.
Теоретические аспекты патриотического воспитания школьников Китая при использовании материалов творчества современных китайских композиторов
Authors: Тянь Е.
Published: October 2024

в статье рассматриваются теоретические аспекты патриотического воспитания китайских школьников при внедрении в процесс обучения материалов творчества современных композиторов Китая. Произведен анализ проблемы патриотического воспитания учащихся средствами музыкальных произведений, выделен современный репертуар патриотического ориентирования, определены некоторые аспекты просветительской деятельности выдающихся китайских композиторов. Актуальность исследования обусловлена необходимостью выделения содержания музыкального материала, который должен стать образцом нравственности и национального достояния для молодого поколения страны. В результате исследования было выявлено единство мнения исследователей, касаемо благоприятного воздействия музыкального наследия на патриотическое воспитание школьников. Основываясь на разнообразии и глубине китайской музыкальной культуры, как современной, так и традиционной, воспитательный процесс включает в себя формирование у студентов почтения к наследию национальной музыки. Подбор музыкальных произведений с акцентом на патриотизм, который соответствует разным уровням сложности, способствует не только расширению знаний учащихся, но и патриотическому воспитанию. Комбинирование музыки и слов, предназначенное для исполнителей различных уровней, направлено на достижение образовательных целей, в том числе на воспитание патриотических, эстетических и моральных ценностей у учеников.

the article examines the theoretical aspects of patriotic education of Chinese schoolchildren when introducing the materials of creativity of modern Chinese composers into the learning process. The analysis of the problem of patriotic education of students by means of musical works is carried out, the modern repertoire of patriotic orientation is highlighted, some aspects of the educational activities of outstanding Chinese composers are identified. The relevance of the research is due to the need to highlight the content of musical material, which should become a model of morality and national heritage for the younger generation of the country. As a result of the study, the unity of opinion of researchers was revealed regarding the beneficial impact of musical heritage on the patriotic education of schoolchildren. Based on the diversity and depth of Chinese musical culture, both modern and traditional, the educational process includes the formation of students' reverence for the heritage of national music. The selection of musical compositions with an emphasis on patriotism, which corresponds to different levels of complexity, contributes not only to the expansion of students' knowledge, but also to patriotic education. The combination of music and words, intended for performers of various levels, is aimed at achieving educational goals, including the education of patriotic, aesthetic, and moral values among students.
Изучение учебных действий и психологических достижений детей с ограниченными возможностями здоровья на начало школьного обучения
Authors: Тушева Е.С. , Овчинникова Т.С.
Published: October 2024

в статье предложена авторская методика по оценке универсальных учебных действий дошкольников на этапе их подготовки к школьному обучению. Анализ достижений в освоении образовательной программы дошкольниками с нарушениями развития, сделанный на этапе поступления их в школу, позволил сделать вывод об уровне сформированности учебных действий и готовности воспитанников к обучению. В связи с этим исследование психологических достижений детей 6-7 с ограниченными возможностями здоровья (ОВЗ) на начало школьного обучения заключается в определении сформированности общих интеллектуальных умений и предпосылок к учебной деятельности. Оно направлено на своевременное выявление трудностей школьного обучения и минимизацию факторов риска школьной неуспеваемости. Тем самым обозначена актуальность рассматриваемой темы.

the article proposes the author's methodology for assessing the universal educational activities of preschoolers at the stage of their preparation for school education. The analysis of achievements in mastering the educational program by preschoolers with developmental disabilities, made at the stage of their admission to school, allowed us to draw a conclusion about the level of formation of educational activities and the readiness of pupils for learning. In this regard, the study of psychological achievements of 6-7 year old children with disabilities (LHA) at the beginning of school education consists in determining the formation of general intellectual skills and prerequisites for educational activities. It is aimed at timely identification of difficulties in school education and minimization of risk factors for school failure. Thus, the relevance of the topic under consideration is indicated.
Роль искусственного интеллекта (AGI) в цифровой журналистике: от производства новостей до взаимодействия со зрителем
Authors: Пань В. , Цзы Е.
Published: October 2024

искусственный интеллект интересует сейчас исследователей всего мира и чаще всего с практической точки зрения, т.е. изучается арсенал используемых цифровых инструментов, их влияние на различные сферы жизнедеятельности человека и диапазон возникающих вследствие этого использования рисков. Журналистика и средства массовой информации как отрасли, способные формировать общественное мнение и определять вектор социального развития, изучаются аналитиками в контексте проникновения ИИ в медиа особенно внимательно. Способности ИИ не ограничиваются генерированием текстового контента, они распространяются намного шире: создание видео и графики, автоматизация процессов, программирование и обработка огромных информационных массивов данных.

artificial intelligence is now of interest to researchers all over the world and most often from a practical point of view, i.e. the arsenal of digital tools used, their impact on various spheres of human activity and the range of risks arising from this use are being studied. Journalism and mass media as industries capable of shaping public opinion and determining the vector of social development are studied by analysts in the context of AI penetration into the media especially carefully. AI's abilities are not limited to generating text content, they spread much wider: creating videos and graphics, automating processes, programming and processing huge amounts of information.
COVID-19 Update: Novavax Vaccine for 2024-2025
Authors:   Editors from The Medical Letter
Published: October 2024

A 2024-2025 formulation of the Novavax adjuvanted protein subunit COVID-19 vaccine that more closely targets currently circulating SARS-CoV-2 variants is available now under an FDA Emergency Use Authorization (EUA) for use in persons ≥12 years old. The 2024-2025 formulations of the mRNA COVID-19 vaccines manufactured by Pfizer/BioNTech (Comirnaty) and Moderna (Spikevax) were licensed by the FDA last month for use in persons ≥12 years old and made available under EUAs for use in persons 6 months to 11 years old.
The Islam dan Peran Politik Wanita: Diskursus antara Marginalisasi dan Pengakuan
Authors: Fikri Sariatul
Published: October 2024

The discourse on the political role of women in Islam is one of the most complex and debated issues in the context of gender equality and religious interpretation. The idea that women have a subordinate position is deeply embedded not only in the minds of men but also in women themselves. This is due to the strong and pervasive patriarchal construction, which emphasizes male superiority and is supported by various institutions such as the state, religion, and culture. This study aims to examine the arguments in the discourse on the political role of women in Islam, trace the roots of marginalization, and efforts to recognize the role of women in politics. This study uses a descriptive qualitative research method with a type of library research, namely reference sources from journal articles, books, and other literature that are relevant to the research theme. The results of the study show that conservative interpretations of religious texts are often used to marginalize the political role of women, associate political leadership with the male realm and emphasize women's domestic roles. This approach is supported by patriarchal cultural and social norms, which have long dominated many Muslim societies.
Optimization of arsenic(III) and mercury(II) removal from non-competitive and competitive sorption systems onto activated carbon
Authors:   , Bayuo Jonas
Published: October 2024

Heavy metals exist in the ecosystem both naturally and due to anthropogenic activities and as recalcitrant pollutants; they are non-biodegradable and cause acute and chronic diseases to human beings and many lifeforms. As a result, the removal of heavy metals from aqueous systems using sorbent materials produced from agricultural wastes is one of the new innovative treatment techniques. In this study, the biosorption and desorption characteristics of heavy metal ions from non-competitive and competitive aqueous solutions onto hybrid granular activated carbon produced from maize residues were investigated. The efficient sequestration of As(III) and Hg(II) ions from both monocomponent and bicomponent synthetic wastewater was found to show dependence on the physicochemical properties of the biosorbent and the studied independent biosorption process factors. The regenerated biosorbent could be reused up to the eighth cycle for the sequestration of As(III) and Hg(II) ions from the synthetic wastewater without significantly losing its adsorptive properties. The applicability of the biosorbent synthesized from the maize residues for the simultaneous decontamination of heavy metals found in real industrial wastewater as a function of several biosorption factors showed that the biosorbent could competitively decontaminate over 96% of As, Hg, Pb, Cd, and Cr in 100 mL textile wastewater in batch mode. The regeneration of the spent biosorbent using 0.10 M HCl showed that the biosorbent is capable of being recycled and reused severally for the sequestration of As, Hg, Pb, Cd, and Cr from the textile wastewater and even up to the ten cycles for a duration of 4 h. The optimization of the competitive removal of As and Hg ions in the co-existence of other heavy metals in the textile wastewater by the CCD-RSM resulted in maximum removal efficiencies of 97.72 and 99.99%, respectively. The characterization of the hybrid granular activated carbon using SEM, TEM, XRD, BET, and FTIR showed that the biosorbent surface characteristics could facilitate the removal of heavy metals from the non competitive and competitive biosorption media. The main biosorption mechanism of the heavy metal ions on the biosorbent was mainly chemisorption involving surface complexation. Therefore, this novel biosorbent is found to be promising and could effectively be employed for heavy metals remediation in aquatic environments. The outcomes of this study are expected to make a significant contribution to the design of low-cost and efficient industrial wastewater treatment systems such as a dynamic batch rector for heavy metal removal using locally available bio-adsorbents.
Valorisation of solid sisal leaves decortication wastes using black soldier fly (hermetia illucens l.) larvae
Authors:   , Konyo Aziza
Published: October 2024

The amount of waste generated from sisal industries during sisal fiber production is huge and its management is still challenging and a menace to the environment. These wastes include sisal wastewater and sisal leaf decortication wastes (SLDW) which represent an opportunity for valorization into products. Nevertheless, the sisal leaf decortication wastes is suitable for resource recovery in order to reduce the impacts it causes by just being discarded in the environment without treatment. This study aimed at managing the SLDW using insect-based technology. Specifically, the study characterized the SLDW for its physical and chemical constituents, pretreatment of SLDW to render it suitable for the growth of the insects and optimization of the waste and other blends for production of livestock feed. The use of SLDW for various applications is limited due to its high acidic content and presence of saponin within it. This is the first study of its kind regarding the use the SLDW as a substrate for growth of BSFL. Pre-treatment was a necessary and challenging step done on the waste to meet minimum requirements for rearing of BSF. The resultant waste had Ca, P, K, Mn, Fe, Cu and Zn at varying levels which are all essential for animal growth. The SLDW contained 10 ± 0.01 percent of crude protein, 11 ± 0.02 moisture and energy (1615 kcal/g of Sisal de-corticated waste). The sun dried BSF larvae reared on SLDW contained 53 ± 0.005 percent crude protein, 4 ± 0.01 percent of crude fat, moisture content (10 ± 0.1) %, carbohydrate (43 ± 0.01) % and ash (37 ± 0.08) %. When rearing was done on SLDW, 3000 g of dried pre-treated waste yielded more wet BSF larvae (336 ± 41.3) g compared to 3000 g of fruit waste which yielded (244 ± 4.16) g of wet BSF larvae. Furthermore, the harvested BSFL after optimization process through blending of SLDW, RB and CDW improved growth rate of BSFL (2.2 gram per larvae) and contained sufficient nutritional value to feed poultry and fish, reducing the necessity to de-fatty the larvae as it is being practiced when market waste is being used. The SLDW is a promising feedstock for rearing BSFL because it has good reduction of the waste by 52%. This study eventually creates resource recovery sustainability in sisal industries.
Investigation of uranium derived from phosphate fertilizers on plants uptakes and bacterial diversity in selected agricultural soils of east africa
Authors:   , Mwalongo Dennis
Published: October 2024

Different types of phosphate fertilizers (PFs) used in agriculture to increase soil fertility contain uranium (U) as an accompanying element. Uranium is both toxic and slightly radioactive. This study investigated the concentrations of U in phosphate rocks (PRs) and PFs used in growing tobacco (Nicotiana tabacum L.) and maize (Zea Mays L) plants from Burundi, Kenya, Rwanda, Tanzania, and Uganda. The results showed that the concentrations of U in phosphates from Burundi, Kenya, Tanzania and Uganda were statistically significant (P ≤ 0.01). The lowest U concentration was 10.7 mg kg−1 found at the Mrima Hill deposit in Kenya and the highest was 631.6 mg kg−1 found at the Matongo deposit in Burundi. Uranium concentrations for local and imported PFs was also statistically significant (P ≤ 0.01). Uranium concentration from PFs ranged from 107.88 ± 9.60 and 281.57 ± 15.82 mg kg−1 . The study also assessed the influence of U from PFs on the radioactivity of agricultural soils and uptake by tobacco plants. The results showed that applications of PFs in agricultural soils increased radioactivity in agricultural soil and tobacco crops. Tobacco smoking and snuffing behaviors resulted in an annual effective dose that was 2.41-6.53 and 1.14-2.45 times greater than annual recommended effective doses for snuffers and smokers. This work also investigated the influence of fertilizer derived U on maize plant uptake and bacterial diversity in soil after application of fertilizers with varying U concentrations. The pilot field experiments showed that application of PFs with different U concentrations influenced bacteria abundance and diversity in maize crops. Applications of Nafaka plus (NP) (3.93 mg kg-1 ) and Minjingu Powder (MP) (3.06 mg kg-1 ) PFs in soil increased bacteria abundance and diversity. Some bacteria were abundant on NP treated soil (high U content) because of their ability to tolerate higher U concentrations. Uptake from soil to crop for maize after applications of PFs of varying U concentrations was investigated by amending soil with Eucalyptus globulus ssp maideii bark and kaolin clay. The soil amendments in reduced U uptake from soil to plant in pot experiments. It is believed that the reduced U uptake is associated with eucalyptus globulus ssp maideni carboxyl groups that can reduce mobile hexa-uranyl ions to immobile tetra uranyl ions that can be absorbed by the kaolin clay. The study recommends further work in understanding the mechanisms of Eucalyptus ssp maidenii bark powder and kaolin U uptake reduction in soil complex matrix.
Reinforcing the civil service ethics to enhance good governance in Nigeria’s Fourth Republic
Authors: Ugbudu Martin
Published: October 2024

An honest, selfless, non-partisan, neutral and accountable civil service is a sine qua non for the realization of the policies and programs of the government meant to enhance the socio-economic well-being of the citizens. This study interrogates the Nigerian Civil Service vis-a vis its core values. The central problematic is to find out whether the Nigerian Civil Service functions in accordance with its ethics? And if not; what is the impact of the collapse of the civil service ethics on the performance of the service; and what can be done to re-invigorate the civil service ethics to enhance effective and efficient service delivery to promote good governance. The study which is analytical relies on secondary sources of data and adopts the Public Choice Theory as its frame work of analysis. The study found out that there is collapse of ethics in the Nigerian Civil Service and this has inadvertently enthroned corruption and undermined its efficiency and effectiveness in policy implementation thus diminishing the sectors’ qualitative input to the development of the country. Amongst, other recommendations, the study suggests improvement in the working conditions of civil servants and strengthening institutions and laws that promote accountability.
Sensibilização com imunoterapia em pacientes com alergia alimentar: uma revisão integrativa da literatura
Authors: Cotta Maria Julia Santana Santos , Murad Thays Caroline Adriano do Nascimento , Cotta Daniel Freitas
Published: October 2024

A alergia alimentar é uma resposta imunológica mediada por IgE a proteínas alimentares, com sintomas variando de leves (urticária) a graves (anafilaxia). A imunoterapia, especialmente a imunoterapia oral (OIT), consiste na administração progressiva de doses do alérgeno alimentar para dessensibilizar o sistema imunológico, reduzindo a intensidade das reações alérgicas. Esta revisão integrativa avaliou a eficácia e segurança da OIT em pacientes com alergias alimentares, com uma busca realizada nas bases PubMed, SciELO, LILACS e Cochrane Library, abrangendo os últimos dez anos. Foram incluídos artigos completos em português e inglês sobre imunoterapia para alergias alimentares. A revisão de 25 estudos mostrou que a OIT reduziu significativamente os sintomas alérgicos e melhorou a qualidade de vida, com destaque para alergias a amendoim, leite e ovo. Uma meta-análise sobre a alergia ao leite de vaca indicou um aumento na tolerância em crianças tratadas com OIT. No entanto, a OIT para alergia a amendoim foi associada a reações alérgicas menores, que demandam atenção cuidadosa. A eficácia da OIT varia conforme a idade e o tipo de alergia, com melhores resultados observados em crianças mais jovens e em alergias a leite e castanhas. Embora promissora, a OIT requer monitoramento rigoroso devido ao risco de reações adversas. Tratamentos personalizados são essenciais para o sucesso terapêutico. A pesquisa contínua é crucial para melhorar a segurança e eficácia da dessensibilização alimentar a longo prazo.
D. Duarte e a Medicina em tempos de peste
Authors: Santos Dulce Oliveira Amarante dos
Published: October 2024

O texto apresenta uma análise da obra do rei Eloquente de Portugal D. Duarte (1433-1438) para destacar seu interesse pela Medicina e sua preocupação com a saúde do reino em tempos de peste. As fontes impressas principais são o Leal Conselheiro e o Livro da Cartuxa, duas versões de apontamentos e ensaios variados entre os quais destaca-se o conhecimento dos saberes da Medicina do século XV. Além de textos médicos, como o Regimento do Estômago, a descrição dos bubões da peste, a fuga dos locais empesteados, enveredou pela practica médica. Assim, coletou diversas receitas de mezinhas compostas contra a peste, das mais simples as mais complexas. Além disso, reuniu outras mezinhas contra outros males que afetavam homens e mulheres. Os conceitos de saúde e enfermidade seguiam a teoria humoral hipocrática -galênica.
The Relative Chronology of the Two Hymnographic Services by Gregory Tsamblak and His Life Path
Authors: Temčinas Sergejus
Published: October 2024

The article presents the results of a comparative analysis of two services composed by Gregory Ciamblak in honour of two martyrs – St. Stefan Dečanski and St. John the New of Suceava – during his stay in Serbia and Moldavia respectively. The formal features of these two services allow us to think that the former was composed earlier than the latter, which was written with greater hymnographic skills. This conclusion, in turn, helps to clarify the controversial issue of the sequence of Tsamblak’s stay in Serbia and Moldavia.
Burnout Among School Teachers in India: A Review of the Literature
Authors:   Shri Venkateshwara University, Uttar Pradesh, Pandey Shruti , Sayed Soofia ,   Shri Venkateshwara University, Uttar Pradesh
Published: October 2024

Among teachers in India, burnout is pervasive and has far-reaching implications for their well-being, efficiency in teaching as well as outcomes of their students. This review seeks to provide a complete literature summary on teacher burnout in the country, addressing its incidence, causatives, ramifications, and possible approaches to handling it. A search through major databases identified 50 relevant papers. It was discovered that teacher burnout in India is characterized by heightened emotional exhaustion cases, depersonalization together with low personal accomplishment rates. Predictors of burnout include excessive workload, lack of autonomy or control unrealistic expectations, poor working conditions and low pay and benefits. Burnout manifests itself through various ways including mental illnesses like depression and physical health problems such as fatigue; loss of productivity; and intentions to quit work soonest possible. The interventions should be based on supporting evidence. These will include workload management strategies for the teachers’ support in decision making processes among other intervention techniques. This paper therefore recommends that evidence-based interventions like workload management strategies and autonomy support systems be put in place to tackle this issue.
Transforming protein research with AI and human expertise
Authors: Rosonovski Summer
Published: October 2024

How a novel machine learning system is bridging the gap between advanced models and expert insights to accelerate protein research Proteins are essential molecules with many critical roles in the body. Determining a protein’s 3D structure helps scientists understand its functions within cells. This is crucial for advances in biology, medicine, and drug design.
New Rules on Inbound Intercompany Financing Transactions
Authors: Karnath S. , Brugger H.
Published: October 2024

As part of the implementation of the Growth Opportunities Act 2024, Germany has introduced new rules on intercompany financing transactions. The article presents the new German rules and analyses them with regard to their compatibility with the OECD Guidelines.
Sarcoma mieloide en íleon: reporte de caso en una paciente sin afectación medular
Authors: Carvajal-Lohr Siria , López-Hurtado Mauricio , Ramirez-Rodriguez Diana P. , Valenzuela-Domínguez Levi R. , Vejar Macías Natalia A.
Published: October 2024

El sarcoma mieloide consiste en la proliferación extramedular de blastos de una o más células de los linajes mieloides. Es una neoplasia extremadamente rara, debido a que tiene una incidencia mundial de 2 casos por cada millón de habitantes en la población adulta. Puede preceder, coexistir u ocurrir después del diagnóstico de leucemia mieloide aguda, siendo esta la forma de presentación más frecuente. Se reporta el caso de una mujer de 30 años con diagnóstico de sarcoma mieloide extramedular a nivel del íleon, sin infiltración de blastos en médula ósea comprobada por biopsia. Inició padecimiento con dolor abdominal en mayo de 2022, se le realizó una resección del íleon y empezó quimioterapia. Actualmente se encuentra en remisión completa demostrada con tomografía por emisión de positrones y en mantenimiento a base de midostaurina. El abordaje del presente caso de sarcoma mieloide aislado tiene un alto valor para la investigación, ya que, además de ser una patología descrita en pocos reportes de caso, la ubicación del sarcoma en la paciente lo convierte en una condición aún más inusual haciendo de su descripción una pieza clave para la evolución en el conocimiento médico.
Financing Expanded Learning Time in Schools: A Look at Five District Expanded-Time Schools
Authors: Kaplan Claire , Farbman David A. , Deich Sharon , Padgette Heather Clapp
Published: October 2024

This report provides preliminary answers to the question of how schools and districts are paying for expanded learning time.
Getting Started With Market Research for Out-of-School Time Planning: A Resource Guide for Communities
Authors: Pokela, Ph.D. Julianne , Steblea Ingrid , Steblea Jeffrey , Shea Linda , Denny, Ph.D Elizabeth
Published: October 2024

This guide—intended for community leaders, policymakers, and afterschool professionals—offers an introduction to using market research to make more informed decisions.
PENGARUH VOLUME KENDARAAN TERHADAP KERUSAKAN JALAN PADA RUAS JALAN LEMBAR SELATAN - KEBUN AYU
Authors: Muda I Nengah Aditya Dwi Ade Sanjaya , Wijaya Lalu Hardi , Aminullah Aminullah
Published: October 2024

Roads are an important factor in ensuring continued comfort and safety for all motorists, based on observations in the field, the condition of the South South Sheet crossing road to Kebun Ayu, which is approximately 5.7 km long, needs to be taken seriously and handled seriously by the government because the condition of the road has many potholes and bumps. The aim of this research is to determine the effect of vehicle volume on the level of road damage, and to determine the relationship between vehicle volume and the level of road damage on flexible pavement.
This research is a case study research on the South South Sheet crossing road to Kebun Ayu. The data used in this research is secondary data such as road data and traffic volume data obtained from the West Lombok Regency Bina Marga service. Meanwhile, primary data obtained directly in the field includes vehicle volume data recorded during peak hours. The results of field data analysis showed that the road damage value (Nr) on the Southsheet – Kebun Ayu road was obtained with an average value (Nr) of 68.2; The traffic volume at peak hours based on passenger car units (pcu/hour) on the Kebun Ayu – South Sheet road is 560 pcu/hour, and in the South South Sheet - Kebun Ayu direction it is 546 pcu/hour. The equation for traffic volume analysis related to the value of road damage and time is Y = 0,025 X1 + 0,101 X2 + 25,74  with the magnitude of R2 or the correlation between variable x and variable y of 0.86 or 86%
Freedom of Expression on the Internet and National Security in Europe: Liberty and Basic Goods
Authors: Tomažič Luka Martin
Published: October 2024

The tension between freedom of expression and the protection of national security is a timeless research problem. Based on the specific historical moment and international political and security situation for Europe in general and the Three Seas region specifically, the aim of this article will be a normative assessment of the appropriate approach to potential limitations on online freedom of expression considering national security. The starting point will be an overview of the state of the art of the European Court of Human Rights practice. Then, the analytical framework of Berlin’s two concepts of liberty will be utilised to differentiate between laissez-faire approaches connected to the first paragraph of Article 10 and the limitations, which are necessary in a democratic society per the second paragraph of Article 10 of the European Convention on the Human Rights and Fundamental Freedoms. In a novel approach to the problem at hand, the main research hypotheses that are subject to analysis are that there is a need for a more nuanced approach to balancing online freedom of expression and national security and that Berlin’s two concepts of liberty, when connected to Finnis’s basic goods, can be a useful normative framework in this regard. The need to differentiate between values and facts while recognising the incommensurability of values will be considered.
Concha de ostión como agregado fino para la elaboración de morteros
Authors: Rodríguez Jiménez Carlos , Ovando García Narciso , López Acopa Nelson de Jesús , Méndez Román Alberto , Romellón Cerino Mario José
Published: October 2024

En esta etapa del trabajo de investigación se evaluaron las propiedades físicas y mecánicas de la concha de ostión (molusco Crassostrea Virgínica) con el objetivo de demostrar su viabilidad como agregado fino para utilizarlo posteriormente en sustitución porcentual de la arena en diferentes proporciones en las mezclas de mortero para finalmente fabricar blocks y adoquines. El proceso fue el siguiente:  Etapa 1.- Se lavaran las conchas de ostión a base de agua, Etapa 2.- Se trituraran las conchas de ostión utilizando herramientas manuales (marro y/o martillo), Etapa 3.- Se procederá a moler la concha de ostión empleando dos molinos manuales, Etapa 4.- Se cribarán las conchas previamente molidas utilizando diversas mallas, hasta que se decida cuáles son las indicadas para separar las partículas en granos finos y gruesos, Etapa 5.- Finalmente, se almacenaran los granos finos y gruesos en contenedores.
Se determinó la granulometría resultante y se dibujó su curva granulométrica correspondiente, se procedió de manera similar con la arena comercial existente en la región, para comparar ambos resultados. El análisis estadístico utilizado se realizó con software y se utilizaron tres métodos fijando en todos los casos el índice de confianza del 95% para las medias, esto nos permitió determinar que la materia prima de concha de ostión si es viable para elaborar productos sustentables que compiten notablemente con los usados tradicionalmente.
Se determinó la granulometría resultante y se dibujó su curva granulométrica correspondiente, se procedió de manera similar con la arena comercial existente en la región, para comparar ambos resultados. El análisis estadístico utilizado se realizó con software y se utilizaron tres métodos fijando en todos los casos el índice de confianza del 95% para las medias, esto nos permitió determinar que la materia prima de concha de ostión si es viable para elaborar productos sustentables que compiten notablemente con los usados tradicionalmente.
医学新质生产力之我见
Authors: 白 春学
Published: October 2024

医学新质生产力是一个相对较新的概念，它指的是应用现代科技手段，特别是互联网、大数据、人工智能和元宇宙等新兴技术，来提升医疗服务质量和效率的能力。这种能力的核心在于创新，包括技术创新、管理创新和服务创新。本文综述了医学新质生产力的技术基础及发展现状，为其发展指明方向，为构建现代医学体系和实现中华民族伟大复兴的中国梦贡献力量。
元宇宙赋能健康管理的意义及展望
Authors: 白 春学 , 王 悦虹 , 蒋 维芃
Published: October 2024

健康管理通过对个体或群体的健康状况进行全面监测、分析和评估，以达到预防疾病、提高生活质量的目的。应用元宇宙技术可以进一步提升健康管理的全面性、精准性、互动性、创新性和个性化，为人们的健康提供更好的保障。然而，也需要注意到元宇宙技术在应用过程中可能存在的数据隐私、技术门槛等问题，需要采取相应的措施进行防范和解决。
面向专病电子病历的实体语料库构建方法
Authors: 陈 思旭 , 刘 独玉 , 谭 小琴 , 齐 星 , 罗 彬
Published: October 2024

本研究针对医疗领域中电子病历命名实体识别任务资源匮乏问题，在医学专家的指导下制定了统一的专病实体语料库标注方法，并构建了2种专病实体语料库——儿童支气管肺炎实体语料库和糖尿病实体语料库。在 BERT-BiLSTM-CRF 和 ERNIE-BiLSTM-CRF 模型上，将儿童支气管肺炎实体语料库与公开数据集进行比较，验证本文提出的专病实体语料库标注方法的有效性；再将专病实体语料库标注方法重新应用于糖尿病电子病历，以评价模型鲁棒性。模型验证结果显示：2种自建专病实体语料库的F1值均优于公开数据集，说明本文提出的专病实体语料库标注方法的鲁棒性。
Metaverse surgical planning with three-dimensional virtual models for minimally invasive partial nephrectomy摘要及解读
Authors: 阿里木 吐尔孙
Published: October 2024

该文作者为Sarah P.Psutka，发表于欧洲泌尿学杂志［1］。文章指出，近期新兴的虚拟可视化技术与人工智能及高速互联网连接的融合，为医学领域元宇宙的发展开辟了道路。在这一完全虚拟的环境里，医务人员能够借助数字化身，对患者的三维虚拟模型（3D VMs）进行直观探讨。文中首次展现了在微创肾部分切除术之前，于元宇宙内开展的术前临床病例讨论实例。外科医生的数字化身在虚拟空间内相聚，并就手术方案及夹闭手段进行了术前虚拟磋商。随后，依据模拟的手术策略执行机器人手术或腹腔镜手术。即便是在虚拟场景下，也彰显了这种沉浸式虚拟现实体验如何跨越地域限制，以及凭借身临其境的直观感受来提升手术规划的质量。未来的研究将进一步增强与模型及虚拟角色间的交互体验［1］。
应用医学新质生产力辅助基层医院筛查和诊断早期肺癌
Authors: 白 春学 , 韦 球 , 魏 雪梅 , 朱 文思 , 胡 洁
Published: October 2024

基层医院在肺癌早期筛查与诊断中扮演着举足轻重的角色。这不仅能够大幅提升患者的生存与治愈率，更能显著改善其生活质量，同时减轻医疗体系的负担，优化资源配置，进而推动相关医疗产业和经济的同步发展。然而，当前基层医院在肺癌筛查与早诊方面仍面临多重挑战。设备技术落后、人员水平参差不齐、资源分配不均、患者认知不足以及政策支持不 够等问题尤为突出。为了克服这些难题，我们需要从多个维度入手，包括更新医疗设备、加强人员培训、优化资源分配、提升患者教育水平以及争取更多的政策支持。
医学新质生产力视角下的雾化治疗前景
Authors: 朱 文思 , 王 悦虹 , 蔡 沁怡 , 白 春学
Published: October 2024

在数字经济时代，新质生产力以数字化、网络化、智能化的新技术为支撑，以科技创新为核心驱动力，以深化高技术应用为主要特征，具有广泛的渗透性和融合性，正深刻改变着各行各业的发展模式。医用雾化治疗是通过将液体药物转化为微小颗粒直接输送至肺部，有效治疗呼吸道疾病如哮喘和慢性阻塞性肺病的方式。新质生产力技术的应用，如物联网、人工智能和元宇宙，为雾化治疗带来了革命性变化。这些技术不仅实现了患者生理数据的实时监测和精准分析，支持个性化治疗方案的制定，还提升了治疗的便捷性和患者的依从性。通过物联网技术，医护人员能远程监控治疗过程，确保治疗的安全性和有效性。同时，人工智能技术的引入提高了数据驱动决策的效率，使得治疗方案更加精准和科学。然而，新质生产力赋能雾化治疗也面临技术接受度、数据安全与隐私保护、经济成本等挑战。未来，随着技术的不断发展和完善，新质生产力将在雾化治疗领域发挥更大作用，推动医疗服务体系的高质量发展。
The metaverse in medicine 摘要及解读
Authors: 王 悦虹
Published: October 2024

作者为 Massimo Massetti 和 Giovanni Alfonso Chiariello，该文发表于欧洲心脏杂志［1］。该文明确 提出元宇宙是一个通过专用的视听设备访问的虚 拟数字世界。在这个平行世界中，各种形式的人工智能相遇，包括以真实人物的数字副本（虚拟形象）形式出现的个体，能够进行社交互动。医学中的元宇宙可以以多种不同的方式使用，可以在相距数千英里的距离内进行远程手术，外科医生可以实时可视化查看患者的临床数据，包括诊断图像，这显然非常有吸引力。它也将可以在与患者临床特征相似的虚拟人身上进行医疗处理和采用药物治疗方案，从而提前观察治疗效果，并显著缩短临床试验的周期。元宇宙还可能会成为卓越的教育工具，提供交互式数字课程的可能性，允许进行解剖和研究详细的解剖结构，不仅用于学习，还能观察病理过程的演变，并提前在虚拟患者身上模拟外科或医疗操作。虽然人工智能已经应用于临床实践，但元宇宙仍处于初始阶段，为了了解其潜在的实用性和可靠性，还需要进一步探究［1］。
Trust, Information Quality, and Reputation: Determinants of Tourist Interest in Lake Toba, Indonesia
Authors: Erizal  , Widodo Slamet
Published: October 2024

Lake Toba has attracted the attention of both local and international tourists. In efforts to enhance tourists' interest in visiting Lake Toba, it is crucial to understand the factors influencing tourists' decisions. This research analyzes the influence of trust, information quality, and reputation on tourists' interest in visiting Lake Toba. Using quantitative methods and Partial Least Squares (PLS) techniques, data were collected from 200 tourists visiting in June 2024. The results indicate that all three variables significantly and positively impact tourists' interest. Trust enhances tourists' confidence in a positive experience, information quality aids decision-making, and a good reputation serves as an indicator of destination quality and safety. Research recommendations include exploring other influencing factors and conducting similar studies in different destinations.
Omni-Channel Marketing Strategy for Lake Toba Indonesia Tourist Destinations in Attracting Foreign Tourists
Authors: Situmorang Milton , Widodo Slamet
Published: October 2024

Lake Toba in North Sumatra, Indonesia, is a region of significant potential for attracting international tourists due to its exceptional natural beauty and cultural richness. However, the current influx of foreign visitors remains low compared to other leading tourist destinations in Indonesia. This research investigates the development and implementation of an omni-channel marketing strategy aimed at enhancing Lake Toba's appeal to international travelers. The study employs a mixed-methods approach, combining qualitative interviews with key stakeholders in the tourism industry and quantitative analysis of tourist behavior data. Key challenges identified include inadequate infrastructure, insufficient promotional efforts, and intense global competition. The research proposes strategies that integrate digital and physical marketing channels, personalize content to meet diverse traveler preferences, and leverage advanced technologies such as artificial intelligence (AI) and virtual reality (VR). The findings suggest that an omni-channel approach can create a more cohesive and engaging tourist experience, thereby increasing Lake Toba's competitiveness in the global market. The research also highlights the broader implications for digital transformation in Indonesia's tourism sector and suggests directions for future studies focused on long-term impacts and scalability of omni-channel strategies.
Analysis Of Home Ownership Credit (KPR) Financing Flpp Prosperity For Customers Low Income (Case Study of Bank BJB Medan Branch Office)
Authors: Ishaq Muhammad Maulana , Widodo Slamet
Published: October 2024

This research aims to evaluate the effectiveness of Sejahtera Home Ownership Credit (KPR) financing through the Housing Financing Liquidity Facility (FLPP) scheme implemented by Bank BJB for Low Income Communities (MBR). The research method used is descriptive qualitative with data collection through in-depth interviews, observation and documentation analysis. The research results show that the FLPP Prosperous KPR program run by Bank BJB has a high level of effectiveness in helping MBR have livable houses. This effectiveness is supported by several factors, including easy access to financing with low interest rates and flexible terms, significant government subsidy support, increasing the welfare of MBR through home ownership, Bank BJB's active role in socialization and education, high levels of realization and customer satisfaction. , as well as good collaboration with developers. With this achievement, the FLPP Prosperous KPR program is proven to be able to provide more affordable financing solutions and contribute to improving the quality of life for MBR. It is hoped that the results of this research can become a reference for developing more inclusive and sustainable banking policies.
The Hindu Icon God Shiva as a Visual Communication of Interactions between the Hindus and the Buddhists at the Borobudur Temple in Indonesia
Authors: Martyastiadi Yusup Sigit
Published: October 2024

In vernacular settlements, it is a common practice to venerate religious icons. The figure of the God Shiva Mahadeva is one of the icons of Hinduism generally venerated in India. Interestingly, this figure is carved on the relief of the Buddhist temple, Borobudur in Indonesia. The visualization shows that the
figure is God Shivam and its presence can be interpreted as a form of visual communication representing the interactions between the Hindu and Buddhist communities living in the surrounding vernacular settlements of the Borobudur temple. This article reviews the art historiography and raises several research questions regarding the visualization of Hindu icons in this Buddhist temple. The study examines the visualization of the figure of God Shiva in one of the
relief panels of the Borobudur temple. The paper employs a case study method. It produces visual comparisons of approaches to artistic practice and art history delineated through the characteristics of the visual elements of God Shiva in the 104 Gandavyuha relief panels. Data was collected through photo documentation, visits to the Borobudur temple, photograph tracing, making lithography, and comparing visual findings with published literature. This is to ensure the accuracy of the visualization and investigate Hindu-Buddhist interactions in Java in the 8th—9th centuries. It concludes that the figure carved on panel 104 in the second gallery of the Gandavyuha reliefs is God Shiva, a Hindu icon as per the Gandavyuha Sutra text where God Shiva is mentioned as a
spiritual guide who has carried out dharma as a bodhisattva.