bluuebunny/crossref_metadata_2025 huggingface dataset:
Health-related quality of life with long-term retention of the PROSthesis of Antibiotic Loaded Acrylic Cement system following infection resolution in low demand patients
Authors: Beaupre Lauren A , Stampe Kyle , Masson Edward , O’Connor Gregory , Clark Marcia , Joffe A Mark , Boychuk Lesia R , Lavoie Guy
Published: June 2017

Background:

The study purpose was to (1) evaluate health-related quality of life (HRQL) with the PROSthesis of Antibiotic Loaded Acrylic Cement (PROSTALAC) in situ for infected total hip arthroplasty (THA), (2) determine infection resolution, and (3) compare subjects who underwent second stage surgery with those who retained the PROSTALAC on a longer term basis.

Methods:

Demographics, physical demand level, and comorbidities were recorded prospectively in 29 subjects followed to at least 24 months after initial PROSTALAC insertion. HRQL was evaluated using the Western Ontario McMaster Osteoarthritis Index (WOMAC) and RAND 36-Item Health Survey. Infection resolution was determined using a pre-specified clinical definition.

Results:

Twenty-five of 29 (86%) subjects’ infections resolved. Three subjects died, of whom two had resolved infections. For survivors, 22/26 (85%) completed HRQL evaluations. After PROSTALAC insertion, pain and function improved within 3–6 months and was retained at 24 months. Of those followed to 24 months, 7/22 (32%) subjects underwent second stage surgery. They were higher physical demand subjects ( p = 0.03) than those not undergoing second stage surgery. We found no difference in WOMAC scores at 24 months between those who underwent second stage surgery and those who retained the PROSTALAC ( p > 0.32).

Discussion:

The PROSTALAC system for THA appears to allow acceptable HRQL while in situ for at least 2 years in low physical demand patients. Subjects with higher physical demand levels are more likely to undergo second stage surgery.

Conclusion:

Further evaluation is required to determine whether longer term PROSTALAC retention may be appropriate for specific patient groups.
Acceptability of Chairside Screening for Racial/Ethnic Minority Older Adults: A Qualitative Study
Authors: Greenblatt A.P. , Estrada I. , Schrimshaw E.W. , Metcalf S.S. , Kunzel C. , Northridge M.E.
Published: June 2017

An aging and more racially and ethnically diverse population, coupled with changes in the health care policy environment, is demanding that the dental profession both redirect and expand its focus. Challenges include providing comprehensive care for patients with complicated medical needs while improving access to care for underserved groups. The purpose of this study is to examine the acceptability of screening for hypertension and diabetes in the dental setting for African American, Puerto Rican, and Dominican older adults who attend senior centers in northern Manhattan, New York City. Focus groups were conducted with 194 racial/ethnic minority men and women aged 50 y and older living in northern Manhattan who participated in 1 of 24 focus group sessions about improving oral health for older adults. All groups were digitally audio-recorded and transcribed for analysis. Groups that were conducted in Spanish were transcribed first in Spanish and then translated into English. Analysis of the transcripts was conducted using thematic content analysis. Five themes were manifest in the data regarding the willingness of racial/ethnic minority older adults to receive hypertension and diabetes screening as part of routine dental visits: 1) chairside screening is acceptable, 2) screening is routine for older adults, 3) the interrelationship between oral and general health is appreciated, 4) chairside screening has perceived benefits, and 5) chairside screening may reduce dental anxiety. Reservations centered on 4 major themes: 1) dental fear may limit the acceptability of chairside screening, 2) there is a perceived lack of need for dental care and chairside screening, 3) screening is available elsewhere, and 4) mistrust of dental providers as primary care providers. This study provides novel evidence of the acceptability of screening for hypertension and diabetes in the dental setting among urban racial/ethnic minority senior center attendees.

Knowledge Transfer Statement: The results of this study may be used by oral health providers when deciding whether to conduct chairside screening for medical conditions such as hypertension and diabetes that could affect, or be affected by, the oral health of their patients. Patient experiences of care—along with clinical outcomes, avoidable hospital admissions, equity of services, and costs—are important outcomes to consider in meeting the needs of an aging and racially and ethnically diverse US population.
ABCA4 Mutation in a Patient With Juvenile Neuronal Ceroid Lipofuscinosis
Authors: Reyes-Capó Daniela , Ventura Camila V. , Tekin Mustafa , Lam Byron L. , Berrocal Audina M.
Published: June 2017

A 5-year-old Ecuadorian male, previously diagnosed with cone-rod dystrophy, presented for a second opinion after experiencing subjective bilateral rapid vision loss over an 18-day period, 4 months prior to consultation. Visual acuity was initially light perception in both eyes. Fundus examination revealed bilateral disc pallor, vascular attenuation, and retinal pigment epithelium atrophy. Electroretinogram showed minimal photopic response and no flicker nor scotopic responses in both eyes. At first, the patient demonstrated normal neurodevelopment. However, over the next 5 years, he developed severe neuromotor limitations and his vision progressed to no light perception in both eyes. Whole-exome sequencing detected CLN3 (p.Gly190Arg) and ABCA4 (p.Phe1026Leu) variant mutations. To the best of our knowledge, this is the first report describing a patient with simultaneous CLN3 and ABCA4 mutations, associated with juvenile Batten disease and inherited diseases of retinal degeneration, respectively.
The hepatocyte-specific HNF4α/miR-122 pathway contributes to iron overload–mediated hepatic inflammation
Authors: Li Min , Tang Yuxiao , Wu Lusha , Mo Fengfeng , Wang Xin , Li Hongxia , Qi Ruirui , Zhang Hongwei , Srivastava Arun , Ling Chen
Published: June 2017

Hepatic iron overload (IO) is a major complication of transfusional therapy. It was generally thought that IO triggers substantial inflammatory responses by producing reactive oxygen species in hepatic macrophages. Recently, a decrease in microRNA-122 (miR-122) expression was observed in a genetic knockout (Hfe−/−) mouse model of IO. Because hepatocyte-enriched miR-122 is a key regulator of multiple hepatic pathways, including inflammation, it is of interest whether hepatocyte directly contributes to IO-mediated hepatic inflammation. Here, we report that IO induced similar inflammatory responses in human primary hepatocytes and Thp-1–derived macrophages. In the mouse liver, IO resulted in altered expression of not only inflammatory genes but also >230 genes that are known targets of miR-122. In addition, both iron-dextran injection and a 3% carbonyl iron–containing diet led to upregulation of hepatic inflammation, which was associated with a significant reduction in HNF4α expression and its downstream target, miR-122. Interestingly, the same signaling pathway was changed in macrophage-deficient mice, suggesting that macrophages are not the only target of IO. Most importantly, hepatocyte-specific overexpression of miR-122 rescued IO-mediated hepatic inflammation. Our findings indicate the direct involvement of hepatocytes in IO-induced hepatic inflammation and are informative for developing new molecular targets and preventative therapies for patients with major hemoglobinopathy.
Clinical and nutritional factors associated with dialysis initiation and mortality in chronic kidney disease
Authors: de Oliveira Mariana Cassani , Tapias Thaysse Montebello , de Góes Cassiana Regina , Martin Luis Cuadrado , Balbi André Luís , Bufarah Marina Nogueira Berbel , Vannini Francieli Cristina Delatim
Published: June 2017

Background

Chronic kidney disease is worldwide recognized as a public health problem due to high rates of morbidity and mortality. At the end stage of the disease, which the glomerular filtration rate is equal or less than 15 ml/min/1.73 m2, dialysis initiation is usually indicated. In the absence of a consensus on the best time of beginning, the aim of this study was to identify clinical and nutritional factors associated with clinical outcomes with the start of dialysis and death.

Methods

In a prospective cohort of 82 patients, clinical (underlying renal disease, renal survival time, systolic and diastolic blood pressure, estimated glomerular filtration rate) and nutritional data (protein intake, anthropometry, bioelectrical impedance test, and strength handgrip) were collected. We used mean and standard deviation or median and association of the variables with the outcome entry into dialysis or death, and a Cox regression model was applied. Statistical significance was p < 0.05.

Results

Fifty-eight patients were included in group 1—G1 (without dialysis)—and 24 patients in group 2—G2 (dialysis). The groups were different in blood urea nitrogen (p = <0.001), serum creatinine (p = 0.003), estimated glomerular filtration rate (p = 0.002), and serum phosphorus (p = 0.002). After multivariate analysis, only serum albumin (HR 0.342, p = 0.004) and glomerular filtration rate (HR 0.001, p = 0.001) were associated with entry into dialysis and death.

Conclusions

We concluded that lower levels of serum albumin and glomerular filtration rate values are associated with entry into dialysis or death.
Impact of Recurrence and Salvage Surgery on Survival After Multidisciplinary Treatment of Rectal Cancer
Authors: Ikoma Naruhiko , You Y. Nancy , Bednarski Brian K. , Rodriguez-Bigas Miguel A. , Eng Cathy , Das Prajnan , Kopetz Scott , Messick Craig , Skibber John M. , Chang George J.
Published: June 2017

Purpose

After preoperative chemoradiotherapy followed by total mesorectal excision for locally advanced rectal cancer, patients who experience local or systemic relapse of disease may be eligible for curative salvage surgery, but the benefit of this surgery has not been fully investigated. The purpose of this study was to characterize recurrence patterns and investigate the impact of salvage surgery on survival in patients with rectal cancer after receiving multidisciplinary treatment.

Patients and Methods

Patients with locally advanced (cT3-4 or cN+) rectal cancer who were treated with preoperative chemoradiotherapy followed by total mesorectal excision at our institution during 1993 to 2008 were identified. We examined patterns of recurrence location, time to recurrence, treatment factors, and survival.

Results

A total of 735 patients were included. Tumors were mostly midrectal to lower rectal cancer, with a median distance from the anal verge of 5.0 cm. The most common recurrence site was the lung followed by the liver. Median time to recurrence was shorter in liver-only recurrence (11.2 months) than in lung-only recurrence (18.2 months) or locoregional-only recurrence (24.7 months; P = .001). Salvage surgery was performed in 57% of patients with single-site recurrence and was associated with longer survival after recurrence in patients with lung-only and liver-only recurrence ( P < .001) but not in those with locoregional-only recurrence ( P = .353).

Conclusion

We found a predilection for lung recurrence in patients with rectal cancer after multidisciplinary treatment. Salvage surgery was associated with prolonged survival in patients with lung-only and liver-only recurrence, but not in those with locoregional recurrence, which demonstrates a need for careful consideration of the indications for resection.
Freedom, Sovereignty, and Other Entanglements
Authors: Bonilla Yarimar
Published: June 2017

Anthropologist Yarimar Bonilla responds to Greg Beckett and Christienna D. Fryar's engagements with her Non-Sovereign Futures: French Caribbean Politics in the Wake of Disenchantment (2015). In responding to the questions raised, Bonilla lays out the conceptual and methodological orientations of the work as well as its analytical targets. The essay situates Non-Sovereign Futures within a larger problem-space of political disenchantment, argues for the need to deprovincialize the Caribbean, and brings into question perduring scholarly entanglements with the traditions of Western political thought.
The effect of sterol structure upon clathrin-mediated and clathrin-independent endocytosis
Authors: Kim Ji Hyun , Singh Ashutosh , Del Poeta Maurizio , Brown Deborah A. , London Erwin
Published: June 2017

Ordered lipid domains (rafts) in plasma membranes have been hypothesized to participate in endocytosis based on inhibition of endocytosis by removal or sequestration of cholesterol. To more carefully investigate the role of the sterol in endocytosis, we used a substitution strategy to replace cholesterol with sterols that show various raft-forming abilities and chemical structures. Both clathrin-mediated endocytosis of transferrin and clathrin-independent endocytosis of clustered placental alkaline phosphatase were measured. A subset of sterols reversibly inhibited both clathrin-dependent and clathrin-independent endocytosis. The ability of a sterol to support lipid raft formation was necessary for endocytosis. However, it was not sufficient, because a sterol lacking a 3β-OH group did not support endocytosis even though it had the ability to support ordered domain formation. Double bonds in the sterol rings and an aliphatic tail structure identical to that of cholesterol were neither necessary nor sufficient to support endocytosis. This study shows that substitution using a large number of sterols can define the role of sterol structure in cellular functions. Hypotheses for how sterol structure can similarly alter clathrin-dependent and clathrin-independent endocytosis are discussed.
Technology and Child Development: Evidence from the One Laptop per Child Program
Authors: Cristia Julian , Ibarrarán Pablo , Cueto Santiago , Santiago Ana , Severín Eugenio
Published: June 2017

This paper presents results from a large-scale randomized evaluation of the One Laptop per Child program, using data collected after 15 months of implementation in 318 primary schools in rural Peru. The program increased the ratio of computers per student from 0.12 to 1.18 in treatment schools. This expansion in access translated into substantial increases in use of computers both at school and at home. No evidence is found of effects on test scores in math and language. There is some evidence, though inconclusive, about positive effects on general cognitive skills. (JEL H52, I21, I24, I28, O15)
Scanning insights on sustainability and supply chain management in Brazil
Authors: Silva Minelle E. , Fritz Morgane M. C. , Nunes Breno
Published: June 2017

This paper aims to analyse how the publications in Brazil are considering the relationship between sustainability and supply chain management. For this end, a literature review was carried out in 120 Brazilian academic journals in which 124 papers were identified, from 2008 until 2013. When considering the Triple Bottom Line approach, the results show that sustainability research in Brazil is focusing on the environmental dimension and SCM research is focusing on the economic dimension. Additional inputs are provided by integrating the governance dimension in the analysis to underline which actions and policies are discussed in Brazil at a corporate level. To support the results a consultation of experts in the field of sustainability in Brazil was fulfilled, and three case examples are presented to explain some of the research results. The findings on publications in Brazil contrast with international studies, particularly on the topic of social performance and management in supply chains. One of the main conclusions is that there are large opportunities to increase publications about sustainability and SCM in the country and that Brazil presents some specificities in the field that researchers and managers shall consider.
Applying inventory classification to a large inventory management system
Authors: May Benjamin Isaac , Atkinson Michael P. , Ferrer Geraldo
Published: June 2017

Inventory classification aims to ensure that business-driving inventory items are efficiently managed in spite of constrained resources. There are numerous single- and multiple-criteria approaches to it. Our objective is to improve resource allocation to focus on items that can lead to high equipment availability. This concern is typical of many service industries such as military logistics, airlines, amusement parks and public works. Our study tests several inventory prioritization techniques and finds that a modified multi-criterion weighted non-linear optimization (WNO) technique is a powerful approach for classifying inventory, outperforming traditional techniques of inventory prioritization such as ABC analysis in a variety of performance objectives.
Should Intangible Investments Be Reported Separately or Commingled with Operating Expenses? New Evidence
Authors: Enache Luminita , Srivastava Anup
Published: June 2017

We propose a new method to estimate intangible investment outlays, other than expenditures on advertising and research and development, that are reported on a commingled basis with operating expenses in the selling, general, and administrative category of expenses. These outlays, aimed at improving organizational knowledge and capabilities, are the largest category of intangible investments and the fastest-growing category of operating investments. They affect future firm performance and risk. Predictability of future earnings and stock returns improves when these outlays are distinguished from operating expenses. Thus, benefits could accrue from reporting them separately.

The SAS program to divide MainSG&A into investment and consumption portions is available at https://doi.org/10.1287/mnsc.2017.2769 .

This paper was accepted by Suraj Srinivasan, accounting.
Positional Anthropometric and Performance Profile of Elite Gaelic Football Players
Authors: Shovlin Aidan , Roe Mark , Malone Shane , Collins Kieran
Published: June 2017

Shovlin, A, Roe, M, Malone, S, and Collins, K. Positional anthropometric and performance profile of elite gaelic football players. J Strength Cond Res 32(8): 2356–2362, 2018—The aim of the current investigation was to evaluate the variation in the anthropometric and performance characteristics of elite Gaelic football players with respect to position. One hundred forty-eight elite Gaelic footballers underwent anthropometric (height, body mass, sum of 7 skinfolds, and % adipose tissue) and performance (counter movement jump [CMJ] height, CMJ peak power, CMJ relative peak power, squat jump [SJ] height, SJ peak power, SJ relative peak power, 5-, 10-, and 20-m sprint times, and Yo-Yo Intermittent Recovery Test Level 2 [Yo-YoIRT2]) during “the early in-season” phase. Data were split into 5 positional groups (full back, half back, midfield, half forward, and full forward). Higher adipose tissue percentage estimate was observed in full forwards when compared with the half backs (p = 0.001), midfielders (p = 0.035), and half forwards (p = 0.021). Full forwards had significantly greater SJ (p = 0.036) and CMJ (p = 0.013) when compared with the midfielders with no other positional differences observed. No significant variation in sprint times was observed across the positions. When Yo-YoIRT2 was considered, full forwards and full backs completed significantly lower distances compared with the middle 3 positional lines of half backs, midfielders, and half forwards (p = 0.00). The current study is the first to provide normative data for anthropometric and performance values of elite Gaelic football players which in turn can be used by coaches to generate appropriate training regimes to maximize position-specific preparation for competitive match-play.
Evidências adicionais da relação entre empreendedorismo e crescimento econômico
Authors: Paula Silvio Da Rosa , Uhr Daniel De Abreu Pereira , Uhr Júlia Gallego Ziero
Published: June 2017

O objetivo deste artigo é investigar a influência do empreendedorismo no crescimento econômico. Utiliza-se três variáveis de empreendedorismo extraídas do Global Entrepreneurship Monitor juntamente com o índice de competitividade global elaborado pelo World Economic Forum, um indicador que captura o conjunto de instituições, políticas e fatores que definem o níveis atuais e médio prazo sustentáveis de prosperidade econômica. Para o modelo empírico utiliza-se o método de dados em painel com controle para efeitos fixos, para o período entre 2006 a 2014. Os resultados demonstram que o empreendedorismo é um fator importante para explicar o crescimento econômico, todavia seu impacto depende do estágio do desenvolvimento econômico dos países.
Descrição de casos de Enterobactérias Produtoras de Carbapenemases subtipos Oxa-48 e NDM em hospital público de Porto Alegre
Authors: Scherer Juliane De Souza , Calvetti Ricardo Andrade
Published: June 2017

Justificativa: A multirresistência bacteriana vem preocupando gestores e profissionais de saúde em esfera global. Neste contexto, a resistência aos carbapenêmicos em enterobactérias é particularmente preocupante em função de sua alta mortalidade (de 40 a 50% em 30 dias) e pelas reduzidas opções de tratamento. Entre as carbapenemases, os subtipos KPC (Klebsiella pneumoniae carbapenemase), NDM (New Delhi Metallobetalactamase) e OXA (Oxa-carbapenemase) são encontrados no estado. Objetivo: descrever os casos de enterobatérias produtoras de carbapenemase (EPC) subtipos OXA e NDM em um hospital público de Porto Alegre. Método: Trata-se de pesquisa transversal, utilizando o banco de dados da Comissão de Controle de Infecção Hospitalar do hospital em estudo. A coleta de dados ocorreu após aprovação do Comitê de Ética em Pesquisa no mês de abril de 2015. A amostra englobou os casos confirmados de EPC subtipos OXA e NDM de janeiro a dezembro de 2013. Resultados: Foram identificados 34 casos de EPC, sendo 22 casos confirmados do subtipo OXA-48 e 12 casos do subtipo NDM. Entre os pacientes portadores do subtipo OXA-48, os homens totalizaram 77,3% e a colonização superou em muito a infecção 81,2%; a mortalidade atingiu 54,5% dos casos, sendo que o microrganismo mais prevalente foi a Klebsiella pneumoniae (45,5%). Os homens somaram 58,4% dos casos de NDM, com predominância de colonizações 83,3% em isolados de Enterobacter cloacae, cuja mortalidade contabilizou 58,3%. Conclusões: A elevada mortalidade e a prevalência de colonizações foram relevantes nesta pesquisa. Portanto, a detecção precoce destes mecanismos de resistência pode contribuir para conter sua disseminação.

Descritores: Resistência microbiana a medicamentos; Controle de infecções; Enterobacteriaceae
Control Region of Mitochondral DNA amplification and sequencing v1
Authors: Feng-ling Xu not provided , Mei Ding not provided , Jun Yao not provided , Zhang-sen Shi not provided , Wang Bao-jie
Published: June 2017

The mtDNA fragment (15869-740) was amplified using primers for polymerase chain reaction (PCR) : L15869F and H719R (L15869 F 5' AAAATACTCAAATGGGCCTGTC 3', H719R5' CGTGGTGATTTAGAGGGTGAAC 3'). The 20 µl PCR reactions contained 2.0 µl 5×buffer, 1.6 µl 2.5 mM dNTP mix, 0.8 µl each of reverse (R) and forward (F) PCR primers (8 pM each), 0.2 µl of KOD Enzyme (1.0 U/µl), and 20 ng of template DNA. PCR was performed under the following cycle conditions: initial denaturation of 94 °C for 5 minutes; followed by 35 cycles of 94 °C denaturation for 30 seconds, 55 °C annealing for 30 seconds, and 72 °C elongation for 40 seconds; followed by a final extension at 72 °C for 10 minutes. The production fragment was sequenced with the following primers: L15869F and 80R for HVSI, 16539F and H719R for HVSII. The purified PCR products were sequenced by ABI 377 DNA automatic sequencer.
DEVELOPMENT OF A GOAT MILK YOGURT FLAVORED WITH THE MANGABA FRUIT (Hancornia speciosa Gomes)
Authors: Santos Elaine Alves , Bessa Vitória Regina , Bonnas Deborah Santesso
Published: June 2017

O leite de cabra apresenta características próprias que o distinguem do leite de outras espécies de animais. Seu uso agrega as características de melhor digestibilidade e possível utilização por pessoas alérgicas ao leite de vaca e seus derivados. Esse trabalho objetivou avaliar as características físico-químicas, microbiológicas e sensoriais de iogurtes produzidos com o leite de cabra com adição de polpa e doce da mangaba (Hancornia speciosa Gomes). Este estudo visou também agregar o aproveitamento das frutas do cerrado brasileiro. Foram utilizadas cinco concentrações (0%, 5%, 6%, 7% e 8%) de polpa e doce de mangaba. No iogurte, foram determinados índice de cor, lipídeos, sólidos soluveis totais (graus Brix), pH, proteína e acidez. Foram realizadas avaliações microbiológicas de coliformes termotolerantes, aeróbios mesófilos e Salmonella sp no iogurte. Os testes sensoriais foram realizados com um grupo de 50 provadores não treinados. Foi usada a escala hedônica estruturada de cinco pontos, com extremos 1 (desgostei muito) e 5 (gostei muito). Foi calculado ainda o índice de aceitabilidade. Para os iogurtes elaborados com polpa e doce de mangaba, apenas o índice de cor e o °Brix obtiveram diferenças significativas. As análises microbiológicas se apresentaram de acordo com os padrões vigentes. Na avaliação sensorial, os resultados encontrados foram satisfatórios. Conclui-se que o iogurte de leite de cabra saborizado com polpa ou doce de mangaba representa uma alternativa promissora para os consumidores alérgicos ao leite de vaca e para aqueles que gostariam de incluir o produto em sua dieta, visando maior digestibilidade.
Construir con tapial: piscina en toro
Authors: Antelo Tudela Enrique , Sánchez Iglesias Santiago , Crespo González Cristóbal , Raya de Blas Antonio
Published: June 2017

Este artículo transmite la experiencia arquitectónica obtenida en la construcción con tapial de grandes muros de cerramiento para una piscina en Toro (Zamora). Partiendo de los aspectos compositivos y espaciales se llega a los técnicos, describiendo las soluciones utilizadas, tales como el postensado del tapial. Se prosigue con la descripción de las incidencias y se propone una serie de medidas a considerar en nuevas construcciones de características similares.
Desarrollo de modelos de análisis numérico mediante la utilización de archivos de intercambio
Authors: Martín Gutiérrez Emilio , Pérez Valcárcel Juan Bautista
Published: June 2017

El presente artículo describe los avances efectuados en el ámbito de la generación de modelos de análisis numérico, combinando técnicas de diseño asistido por ordenador y de programación para lograr un intercambio de información entre aplicaciones de diferente propósito. Esto permite mejorar el proceso, usando en cada fase las herramientas que específicamente pueden optimizarla. El planteamiento ha resultado especialmente útil en estudios de estabilidad realizados sobre edificaciones con valor histórico o con singularidades geométricas de todo tipo. En estos casos, la gran complejidad del modelo dificulta extraordinariamente su introducción, si sólo se utilizan las herramientas de preproceso convencionales.
Sacralización, culto y religiosidad en la arquitectura latinoamericana
Authors: Fernández Cobián Esteban
Published: June 2017

Reseña de libro
El autor y el intérprete. Le Corbusier y Amancio Williams en La Casa Curutchet
Authors: Amado Lorenzo Antonio
Published: June 2017

Revisión de libro
Las universidades laborales gallegas. Arquitectura y modernidad
Authors: Blanco Agüeira Silvia
Published: June 2017

Revisión de libro
Metáforas ocultas en los espacios de la muerte actuales
Authors: Pérez Naya Antonia
Published: June 2017

Los espacios funerarios tradicionalmente contienen variados catálogos de imágenes simbólicas que trasmiten mensajes reconocidos por el colectivo social. Por el contrario, en los actuales, ya no limitados exclusivamente a los cementerios, se percibe un enfoque más contenido y aséptico, con metáforas ocultas apenas perceptibles, reinterpretadas desde la perspectiva de la muerte actual. Testimonio evidente de que la arquitectura es un claro reflejo y una consecuencia directa de la sociedad que la genera.
Evocar atmósferas. Arquitectura suiza contemporánea y su expresión visual del proyecto
Authors: Fernández Morales Angélica
Published: June 2017

El artículo se centra en la escena suiza contemporánea, y presenta diversos ejemplos de cómo es expresada visualmente la esencia atmosférica en el proyecto arquitectónico. El texto se estructura relacionando la atmósfera con varios aspectos: el lugar, la escala humana, la luz y el aire. Entre los arquitectos tratados se incluyen Herzog and de Meuron, Peter Zumthor, Christian Kerez, Gigon and Guyer, Miroslav Šik y Philippe Rahm. Se distinguen dos modos de expresión: los de carácter abstracto y diagramático y los que buscan la previsualización realística. En ambos casos, lo importante es la capacidad de evocar la vivencia de la arquitectura proyectada.
Xulio Turnes, Ramón Viéitez y Noemí Díaz. N-550 Da estrada á rúa. As vivendas illadas
Authors: Río Vázquez Antonio Santiago
Published: June 2017

Reseña de libro
Silvia Blanco Agüeira. Iglesia de los Sagrados Corazones de Madrid. Arquitectura y arte
Authors: Río Vázquez Antonio Santiago
Published: June 2017

Reseña de libro
Продовольственная безопасность России
Authors: Ларионов Валерий Глебович
Published: June 2017

В статье рассматриваются особенности продовольственной безопасности России, состояния агропромышленного комплекса страны, объемы поддержки сельского хозяйства развитых зарубежных стран, задачи, стоящие перед нашей Родиной для обеспечения продовольственной безопасности.
Предмет. На протяжении всей истории человечества обеспечение продовольствием оставалось одной из наиболее актуальных проблем национальной безопасности всех государств мира. С созданием Организации Объединенных Наций (ООН) мировое сообщество стало уделять пристальное внимание преодолению дефицита продовольствия.
Методология. Цель и задачи. Термин «продовольственная безопасность» означает такое состояние экономики и агропромышленного комплекса страны, которое, при сохранении и улучшении среды обитания, независимо от внешних и внутренних условий, позволяет населению страны бесперебойно получать экологически чистые и полезные для здоровья продукты питания по доступным ценам, в объемах не ниже научно обоснованных норм.
Результаты. По определению ФАО, продовольственная безопасность – четко функционирующая система, обеспечивающая все слои населения продуктами питания по принятым физиологическим нормам.
Выводы. Продовольственная безопасность страны может быть обеспечена только в рамках комплексного подхода, при этом ее базовые составляющие должны быть закреплены на законодательном уровне.
Оценка продовольственной безопасности региона: вопросы методологии
Authors: Антамошкина Елена Николаевна
Published: June 2017

Анализ продовольственной безопасности, как правило, проводится на уровне государства, в соответствии с показателями и рекомендациями, установленными в Доктрине продовольственной безопасности Российской Федерации. Однако формируется продовольственная безопасность прежде всего на региональном уровне, что позволяет обеспечить в масштабах страны национальную продовольственную безопасность. Для оценки продовольственной безопасности экономики региона на сегодняшний день не существует достаточно разработанной комплексной методики, что и определяет актуальность проводимого исследования.Статья посвящена обоснованию авторской методики анализа продовольственной безопасности на региональном уровне экономики и ее апробации на примере Южного Федерального округа (ЮФО). Цель автора заключалась в разработке комплексной универсальной методики анализа региональной продовольственной безопасности. Для достижения поставленной цели потребовалось: разработать систему показателей оценки продовольственной безопасности; определить критерии оценки; синтезировать модель анализа и оценки продовольственной безопасности региона. В статье представлен алгоритм поэтапного применения методики оценки региональной продовольственной безопасности.Разработана модель, основанная на универсальной методике оценки продовольственной безопасности на региональном уровне экономики, отличительными особенностями которой от существующих является ее комплексность и универсальность, позволяющая проводить сравнительный анализ уровня продовольственной безопасности по регионам страны и предлагать корректирующие меры в рамках агропродовольственной политики с учетом требований ВТО. Теоретическая значимость заключается в содержательном дополнении исследований моделей и инструментов анализа продовольственной безопасности на региональном уровне экономики с точки зрения обоснования показателей и критериев оценки продовольственной безопасности региона в условиях участия России в ВТО. Практическая значимость состоит в разработке и апробации предложенной методики на основе оценки показателей продовольственной безопасности ЮФО.Работа выполнена при финансовой поддержке РГНФ и Администрации Волгоградской области, проект № 15–12–34006 «Оценка эффективности агропродовольственной политики на региональном уровне».
Особенности государственной поддержки сельского хозяйства в современных условиях
Authors: Тимощенко Марина Александровна
Published: June 2017

Агропромышленный комплекс, а также его базовая отрасль – сельское хозяйство – выступают значимыми сферами российской экономики, обеспечивающими продовольственную безопасность государства как составную часть экономической безопасности, формирующими рынок сельскохозяйственной продукции, способствующими развитию сельских территорий. Задача обеспечения населения качественным, безопасным продовольствием отечественного производства стоит перед любым государством. Особенно актуальна данная задача стала для Российской Федерации в связи с возникновением ряда вызовов и угроз для отечественного агропромышленного комплекса, когда проблема преодоления продовольственной зависимости страны встала наиболее остро. Решение данной проблемы невозможно без активного вмешательства государства. Актуальность темы исследования обусловлена необходимостью формирования на современном этапе эффективной модели оказания государственной поддержки сельскохозяйственным товаропроизводителям для формирования конкурентоспособного рынка отечественной сельскохозяйственной продукции и успешной реализации политики импортозамещения. Данное исследование позволило выявить и проанализировать основные факторы, оказывающие влияние на современный агропродовольственный рынок Российской Федерации. Анализ современных условий функционирования отечественного сельского хозяйства может быть использован при разработке основных направлений аграрной политики в очередном финансовом году. При разработке или внесении изменений в меры поддержки сельскохозяйственных товаропроизводителей также необходимо учитывать современные условия, а также анализировать результаты проводимой политики и осуществлять, при необходимости, ее своевременную корректировку.
OFICINA PEDAGÓGICA NA CONSTRUÇÃO DE CONHECIMENTOS SOBRE ARBOVIROSES
Authors: Mascarenhas Priscila Meira , Lopes Valéria Marques , Silva Maílla Dos Santos , Da Silva Geslaney Reis , Duarte Ana Cristina Santos , Boery Rita Narriman Silva de Oliveira
Published: June 2017

Objetivo: descrever o uso da oficina pedagógica como um espaço de construção, reflexão e problematização da realidade. Método: Relato de experiência. Foi realizada uma oficina pedagógica com 10 estudantes do curso de Licenciatura em Ciências Biológicas de uma Universidade Estadual do Sudoeste da Bahia – Brasil, em maio de 2016, sobre a temática dengue, zika e chikungunya, com a aplicação de um pré-teste e de um pós-teste. Resultados: O grupo possuía conhecimentos acerca do tema, demonstrando não ser algo novo devido à divulgação por meios de comunicação. Observou-se a necessidade de esclarecimentos quanto à diferenciação de sinais e sintomas, e reforço em algumas medidas preventivas, o que foi abordado no decorrer da intervenção. Conclusão: A oficina contribuiu para a propagação de conhecimento sobre a temática, permitiu fomentar a associação teoria-prática a partir de uma realidade vivida que precisa ser trabalhada, inquietando os participantes a serem atores sociais nesse processo.

 

Descritores: Dengue; Zika Vírus; Vírus Chikungunya; Conhecimento. 
PERCEPÇÃO DE MÃES DE RECÉM-NASCIDOS PREMATUROS HOSPITALIZADOS ACERCA DA AMAMENTAÇÃO
Authors: Bezerra Marcela Jucá , Carvalho Amanda Cordeiro de Oliveira , Sampaio Karla Jimena Araújo de Jesus , Damasceno Simone Soares , Oliveira Dayanne Rakelly de , Figueiredo Maria De Fátima Esmeraldo Ramos de
Published: June 2017

Objetivo: compreender como as mães percebem o processo de amamentação de seu filho prematuro hospitalizado na Unidade de Terapia Intensiva Neonatal. Método: estudo descritivo-exploratório de abordagem qualitativa, realizado com oito mães em uma cidade do interior do Ceará, Brasil. Os dados foram coletados por meio de entrevista semiestruturada entre agosto e setembro de 2015. Realizou-se a análise de conteúdo das falas. Resultados: evidenciou-se a percepção da amamentação como importante para a criança no que diz respeito ao crescimento, desenvolvimento e recuperação hospitalar. Dificuldades relacionaram-se à quantidade e ejeção do leite. A realização da ordenha para as mães foi percebida como técnica não similar ao aleitar e geradora de dificuldades. Conclusão: a amamentação ao seio é percebida como uma conquista alcançada pelos esforços conjuntos do binômio mãe e filho.

Descritores: Mães; Prematuro; Aleitamento Materno; Unidades de Terapia Intensiva Neonatal.
Trafność prognozowanego poziomu migracji w pracach GUS
Authors: Kałuża-Kopias Dorota
Published: June 2017

W artykule dokonano oceny trafności przewidywanego poziomu migracji w prognozach opracowanych przez Główny Urząd Statystyczny w ostatnich dwóch dekadach (prognozy z lat: 1997, 2000, 2004, 2009). W artykule omówiono migracje (wewnętrzne i zewnętrzne) we współczesnej Polsce. Następnie przedstawiono i skomentowano założenia metodologiczne z wybranych prognoz dotyczących migracji. Wskazano, iż różnice między rzeczywistą skalą migracji a przewidywaną z prognoz były stosunkowo duże. Błędy dotyczyły zarówno wyznaczania właściwych trendów w kierunkach migracji, jak i rozmiarów przemieszczeń.
Problematyka mieszkalnictwa w badaniach Profesora Jerzego Dzieciuchowicza
Authors: Matczak Andrzej
Published: June 2017

W Polsce po II wojnie światowej przeprowadzono inwentaryzację stanu mieszkań w miastach. Prowadzono ją w ramach studium inwentaryzacji urbanistycznej. Do badań tych aktywnie włączył się łódzki ośrodek geograficzny. Geografowie z ośrodka łódzkiego przeprowadzili szereg studiów inwentaryzacji urbanistycznej w miastach Śląska Opolskiego, Kielc i Łodzi. Na ich podstawie przedstawiono szereg opracowań dotyczących zróżnicowania przestrzennego i szczegółowej rejonizacji warunków mieszkaniowych w paru miastach Śląska Opolskiego, centrum Kielc i w Łodzi. Badania te oparto na bezpośrednich kwerendach terenowych oraz na materiałach Narodowych Spisów Powszechnych (NSP). W badaniach tych aktywny udział brał Profesor Jerzy Dzieciuchowicz. Problematyka mieszkalnictwa, a zwłaszcza rejonizacja warunków mieszkaniowych w Łodzi, stanowiła w dorobku naukowym Profesora ważny nurt badawczy w okresie 1972‒2012. Przeprowadzone w tym okresie studia empiryczne podsumowuje prezentacją systemowej propozycji badań w postaci szeroko ujętego modelu środowiska mieszkaniowego.
Budownictwo mieszkaniowe w strefie podmiejskiej Wrocławia
Authors: Ciok Stanisław
Published: June 2017

Strefy podmiejskie dużych miast ulegają znacznym zmianom w zakresie gęstości i metod zagospodarowania przestrzennego. Metoda zagospodarowania rolniczych obszarów wiejskich wykorzystywana do dziś, której charakter jest jednolity na przestrzeni całego kraju, pod względem napływu ludności, dużego ruchu budowlanego, pojawiania się różnych inwestorów, nowych funkcji nierolniczych itd. zmienia obraz obszarów wiejskich, przeważnie na modłę miejską. W artykule skupiono się na analizie ruchu budowlanego w strefie podmiejskiej Wrocławia. Na obszarze tym ruch budowlany rozwija się najdynamiczniej (w okresie 2008‒2009 aż 44,4% wszystkich budynków mieszkalnych realizowanych na obszarach wiejskich województwa dolnośląskiego zostało wzniesionych i oddanych do użytku w 9 gminach bezpośrednio graniczących z Wrocławiem). Analiza ruchu budowlanego oraz zmian morfologii osiedli wywołanych tym procesem została poprzedzona analizą sytuacji demograficznej. Problem zarządzania mieszkaniowego nie może zostać poddany analizie bez odniesienia go do sytuacji demograficznej oraz procesów ją tworzących. Ruch budowlany jest ściśle powiązany z sytuacją demograficzną. Jest to szczególnie znaczące w przypadku województwa dolnośląskiego, gdzie bieżąca sytuacja demograficzna jest pokłosiem wielu historycznych, społecznych, ekonomicznych oraz politycznych zjawisk i procesów, nierzadko odmiennych od tych zachodzących na innych obszarach kraju.
La persistencia de la ambigüedad: enseñanzas imprevistas de Comino
Authors: Núñez César Andrés
Published: June 2017

El presente artículo analiza la obra para guiñol Comino vence al diablo, de Germán List Arzubide, con el fin de estudiar los cambios estéticos producidos en su obra en la década de 1930. La obra fue, además, un texto fundacional –y a la vez modélico– del Teatro Guiñol de Bellas Artes. El análisis permite, a la vez, reflexionar sobre el complejo paso de las vanguardias de la década anterior al arte comprometido que desarrolla el autor (y tantos otros artistas con un recorrido estético semejante) en esos años y proponer alguna posibilidad de explicación en torno a las rupturas y continuidades de ese tránsito.
Gabriel Wolfson (compilador) Se acabó el centenario: lecturas críticas en torno a Octavio Paz. México: UDLAP, 2015.
Authors: Ismael Simental María Emilia
Published: June 2017

Se acabó el centenario: lecturas críticas en torno a Octavio Paz es una publicación que, como su título bien indica, apuesta por una lectura del poeta mexicano y su obra más allá de las celebraciones nacionalistas y el culto a la figura en el despliegue de homenajes provocados por el aniversario de su nacimiento. La compilación realizada por Gabriel Wolfson recoge la mayoría de los trabajos y discusiones presentadas en el coloquio del mismo nombre celebrado en noviembre de 2014 en el campus de la Universidad de las Américas Puebla, en Cholula. Es una compilación que tiene de todo y para todo tipo de lector. El resultado es, sin duda, una herramienta para examinar a Paz en sus diversas facetas pero, más importante aún, una provocación para interrogar en sus múltiples dimensiones a aquello que llamamos quehacer literario en México y al país mismo desde la literatura.
Educação socrática
Authors: Bolzani Filho Roberto
Published: June 2017

Este texto pretende apresentar e comentar as principais características da filosofia socrática, tal como elaborada em diálogos platônicos, que permitem compreender em que sentido essa filosofia pode ser vista como uma forma de ensino e aprendizado.
O atendimento à criança excepcional no instituto Pestalozzi de Minas Gerais (1940-1949)
Authors: Lourenço Erika , Turci Deolinda Armani , Miranda Ciléia Saori Hamada de , Martins Carolline de Souza
Published: June 2017

O Instituto Pestalozzi foi fundado em Belo Horizonte, MG, em 1935, como uma escola para crianças com deficiência intelectual. Esta pesquisa teve como objetivo investigar como era realizado o atendimento à criança excepcional nessa instituição durante a década de 1940. Utilizando como referencial a historiografia da psicologia, foram analisados 33 prontuários de crianças atendidas no Instituto no período em questão. Esses documentos revelaram que as crianças passavam por uma avaliação médica, psicológica e educacional. A avaliação psicológica incluía a aplicação de testes de inteligência e, geralmente, identificava um QI abaixo da média. Os prontuários indicam também as recomendações de tratamento que eram feitas aos pacientes, bem como sua evolução escolar. Observa-se que o Instituto Pestalozzi exerceu importante papel na educação da criança excepcional em um período histórico em que era comum seu alijamento do sistema público de ensino.
Design of a Closed-Loop Supply Chain with Stochastic Product Returns
Authors: Ishigaki Aya , Yamada Tetsuo , Gupta Surendra M. ,   Tokyo University of Science 2641 Yamazaki, Noda, Chiba 278-8510, Japan,   ;,   The University of Electro-Communications, Tokyo, Japan,   Northeastern University, Boston, USA
Published: June 2017

This research focuses on the relation between time variation and the behaviors of a closed-loop supply chain with stochastic product returns. In recent years, activities that reduce environmental impact, such as recycling and reusing materials, have been increasing. Designing a closed-loop supply chain for recycling or reuse operations will support social responsibility and competitive advantage. However, in order to establish supply chains for sustainability, it is necessary to consider not only environmental benefits but also economic efficiency. Moreover, both the quantity of demand and returns are indefinite in an actual closed-loop supply chain. In this study, we assume that the arrival interval of return inward follows a logarithmic normal distribution. Further, we design basic models with a manufacturing and remanufacturing process to understand the behavior of a closed-loop supply chain with stochastic product returns in a finite horizon and investigate the influence of different choices in management on the cost and environmental factors.
Development and Validation of RP-HPLC Method for the Estimation of Sitagliptin Phosphate in Tablet Dosage Form
Authors: D Sireesha , E Sai Lakshmi , E Sravya , Bakshi Vasudha
Published: June 2017

A new simple, rapid, specific, accurate, precise and novel Reverse Phase High Performance Liquid Chromatography (RP-HPLC) method has been developed for the estimation of Sitagliptin Phosphate in the pharmaceutical dosage form. The chromatographic separation for Sitagliptin was achieved with mobile phase containing methanol, Thermoscientific C18 column, (250x4.6 particle size of 5μ) at room temperature and UV detection at 248 nm. The compounds were eluted in the isocratic mode at a flow rate of 1ml/min. The retention time of Sitagliptin was 1.91min. The above method was validated in terms of linearity, accuracy, precision, LOD and LOQ in accordance with ICH guidelines.
Synthesis of carboxyl-introduced chitosan with C2 amine groups protected and its use in copper (II) removal
Authors: Dong Liu , Wen Cheng , Junxia Yu , Yigang Ding
Published: June 2017

A route for the formation of carboxyl-introduced chitosan (CI-CS) with C2 amine groups protected (CIAP-CS) was investigated to improve copper (II) adsorption. First, the C2 amine groups of the chitosan (CS) were protected via a Schiff-base reaction by benzaldehyde. Then the product was obtained by the introduction of pyromellitic dianhydride to the C6 hydroxyl groups on CS via epichlorohydrin. The last product was obtained by removing the Schiff base with dilute hydrochloride solution. CI-CS without C2 amine groups protected was directly synthesized as well. The adsorbents were characterized by Fourier transform infrared (FTIR), X-ray diffraction (XRD) and X-ray photoelectron spectrometer (XPS). The adsorption properties for copper (II) were investigated. FTIR spectroscopy and XPS clearly showed that most of the amine groups in CS were converted to –N = CH2 groups after the benzaldehyde treatment and that no cross-linking reactions with CS were involved; the HCl treatment after the cross-linking reaction effectively released nitrogen atoms protected into the form of the primary amine again. The results confirm that the CIAP-CS cross-linked with the new method had significantly greater adsorption capacities than the CI-CS cross-linked directly with CS. Mechanism study revealed that the increased adsorption performance is attributed to the large number of primary carboxyl and amine groups available on the surfaces of the CIAP-CS. The adsorption mechanism is based on ion exchange and chelating action, and the adsorption process is mainly chemisorption.