bluuebunny/crossref_metadata_2025 huggingface dataset:
Estimating uncertainties in external and internal radiation doses in people resided in contaminated regions of Russia after the Chernobyl accident with the use of instrumental data
Authors:   A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (A. Tsyb MRRC), Vlasov O.K. , Bruk G.Ya. ,   P. Ramzaev Research Institute of Radiation Hygiene, Zvonova I.A. ,   P. Ramzaev Research Institute of Radiation Hygiene, Shchukina N.V. ,   A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (A. Tsyb MRRC)
Published: December 2022

The paper presents the results estimation of uncertainties in doses to the thyroid, from external and internal exposure to radiation following the Chernobyl accident. For the estimation the data-base of radiometry activities of Cs-134+137 in the body and I-131 to the thyroid in 1986 for 28,311 residents of Kaluga region and 16,470 residents of Bryansk region. Whole body radiation spectrome-try measurements made for 167,325 residents of Bryansk region from 1990 through 1994 were used. The computational model for reassessment of I-131 activities into individual exposure doses is an analytical relationship that describes the relative dynamics of radionuclide activities in a chain consisting “vegetation”, “milk”, “thyroid” and “inside the human body”, that is the chain of successive single-chamber models with time-constant transition rates between chambers and depending on the age of a person after single deposition of radionuclides on vegetation. The dy-namics of specific activities of I-131, Cs-134+137 in the vegetation chamber is calculated according to the agroclimatic model, with account of the dynamics of precipitation, the growth of forage and food vegetation biomass according to the data of the annual variation of average daily air tem-peratures in the surface layer of the atmosphere. The official methodology was used to calculate external exposure doses and reassess whole body radiation spectrometry measurements into in-ternal exposure doses. Based on the results of the studies, uncertainty estimates were obtained in terms of standard geometric deviations in the year of the accident – for individual, average in populated areas and integral dose estimates: (minimum/average/maximum) doses of internal thyroid and whole body exposure, respectively (1.1/2,0/3.0), (1.2/1.5/2.3) and (1.3/2.9/3.3); for doses since 1987, respectively (1.2/1.9/4.0), (1.2/1.9/2.1) and (1.4/5.2/8.2). The uncertainty of the calculation model for internal doses since 1987 is estimated at 2.1 times; the uncertainties estimated from the data of individual dosimetry of external and internal exposure of the population with the allocation of critical groups are equal to 1.5 and (1.9-2.2) times, respectively.
Accumulation of Cs-137 and Sr-90 by lettuce culture (Lactuca sativa L.) from radioactively contaminated soils of the former Semipalatinsk test site
Authors:   Branch of «Institute of Radiation Safety and Ecology» National Nuclear Center of the Republic of Kazakhstan, Polivkina Ye.N. , Ponomaryova T.S. ,   "ECOEXPERT" LLP, Karaganda, Mendubaev A.T. ,   Branch of «Institute of Radiation Safety and Ecology» National Nuclear Center of the Republic of Kazakhstan, Kenzhebaev R.A. ,   Branch of «Institute of Radiation Safety and Ecology» National Nuclear Center of the Republic of Kazakhstan, Nemytova L.A. ,   Branch of «Institute of Radiation Safety and Ecology» National Nuclear Center of the Republic of Kazakhstan, Ivanova A.R. ,   Branch of «Institute of Radiation Safety and Ecology» National Nuclear Center of the Republic of Kazakhstan, Kenzhina L.B. ,   "ECOEXPERT" LLP, Karaganda, Panitskiy A.V. ,   Branch of «Institute of Radiation Safety and Ecology» National Nuclear Center of the Republic of Kazakhstan
Published: December 2022

The paper presents the study of Cs-137 and Sr-90 transfer from soils of the former technical sites of the Semipalatinsk test site to the salad culture (Lactuca sativa L.) as an example of the leaf vege-table. The factors affecting the transfer of the radionuclides from soils with a different character of radioactive contamination to the salad culture were identified under the model vegetation ex-periment conditions. The variation ranges of Cs-137 and Sr-90 transfer factors values were 2 and 1 orders of magnitude respectively. With the use of the private correlation method, it was found that the content of biologically available forms of Cs-137 and Sr-90 in the soils of the former Semipala-tinsk test site, and, consequently, accumulation of these radionuclides by the salad, depended on their nonisotopic analogs K and Ca concentration in the soil, respectively (rxy–z=-0.81; n=4, p<0.2 – for Cs-137 and gross K; rxy-z=-0.64; n=4, p<0.2 – for Sr-90). There was a moderate positive relationship between the value of Cs-137 transfer factor and physical clay content (fraction >0.01%) in the soil (ρ=0.47; n=12, p<0.05), the relationship between value of Sr-90 transfer factor and the physical clay content was weak negative (ρ=-0.3; n=11, p<0.05). The migration of Cs-137 and Sr-90 to the salad culture from the radioactively contaminated soils of the Semipalatinsk test site mainly depended on biologically available forms content of radionuclides and their non-isotopic analogs K and Ca speciation, respectively. The impact of physical clay on the accumulation of Cs-137 and Sr-90 by the salad culture was less pronounced, it could be due to the specific conditions for radioactive contamination of the soil surface in the territory of the former technical sites of the Semipalatinsk test site.
Комплексы вакансия галлия --- мелкий донор в n-GaAs, легированном элементами VI группы Te или S (О б з о р)
Authors: Гуткин А.А. , Аверкиев Н.С.
Published: December 2022

Рассмотрены результаты исследований комплексов вакансия Ga (VGa) --- мелкий донор (атом Te или S, замещающий атом As в ближайшем к вакансии узле решетки) методами фотолюминесценции при резонансном поляризованном возбуждении и пьезоспектроскопии. Анализ экспериментальных данных в классическом дипольном приближении показывает, что симметрия комплексов ниже тригональной и их оптические свойства объясняются в модели моноклинного дефекта, имеющего плоскость симметрии типа \011\, в которой лежит исходная тригональная ось и ось оптического диполя. Причиной понижения симметрии исходно тригонального центра являются дисторсии, возникающие из-за эффекта Яна-Теллера. Предложена микроскопическая модель, связывающая особенности поведения оптических свойств комплекса VGaTeAs при одноосных деформациях и изменении температуры с особенностями структуры электронных уровней и изменением зарядового состояния комплекса. Различия в этом поведении, наблюдавшиеся для комплекса VGaSAs, анализируются и возможные причины их появления обсуждаются. Ключевые слова: вакансионные комплексы в GaAs, эффект Яна-Теллера, фотолюминесценция при резонансном возбуждении, пьезоспектроскопия.
Спонтанная эмиссия в утекающие моды нанопроводов
Authors: Николаев В.В. , Гиршова Е.И. , Калитеевский М.А.
Published: December 2022

Получены алгебраические выражения для вероятности спонтанного излучения в утекающие моды для эмиттеров в нанопроводе, ориентированных радиально, аксиально и азимутально по отношению к оси нанопровода. Рассчитаны диаграммы направленности и зависимости вероятности спонтанной эмиссии от положения эмиттера. Показано, что при определенных значениях диаметра нанопровода вероятность спонтанной эмиссии на границе нанопровода может увеличиваться на порядок, и возможно формирование узкой  диаграммы направленности. Ключевые слова: нанопровод, спонтанная эмиссия, утекающие моды.
Создание темплейтов для гомоэпитаксиального роста 3C-SiC методом прямого сращивания пластин карбида кремния различающихся политипов
Authors: Мынбаева М.Г. , Амельчук Д.Г. , Смирнов А.Н. , Никитина И.П. , Лебедев С.П. , Давыдов В.Ю. , Лебедев А.А.
Published: December 2022

An approach of direct bonding of SiC wafers of differing polytypes has been implemented in order to create a template for cubic 3C-SiC homoepitaxy. Heteroepitaxial 3C-SiC layers grown by chemical vapor deposition were transferred onto a hexagonal 6H-SiC wafer. The results of structural characterization showed that the quality of 3C-SiC sublimation epitaxy on the templates is comparable to the level of epitaxy of cubic silicon carbide by chemical vapor deposition method. It was confirmed that the 3С-SiC layer transferred onto the 6H-SiC substrate plays the role of a crystalline "seed" that determines cubic polytype of the overgrown SiC layer.
Спектры излучения воздуха низкого давления при диффузном стримерном разряде
Authors: Тарасенко В.Ф. , Бакшт Е.Х. , Виноградов Н.П. , Сорокин Д.А.
Published: December 2022

Attention to the study of the radiation characteristics of streamer discharges in atmospheric air at pressures of a fraction of a Torr unit is primarily associated with obtaining new data on high-altitude discharges, including red sprites. This paper presents the results of studying the characteristics of the radiation of a streamer discharge in low-pressure air upon initiation of ionization waves (streamers) by a repetitively pulsed barrier discharge. It has been established that at air pressures of 0.08 – 3 Torr, the lines of the second positive, first negative, and first positive nitrogen systems have the highest intensities in the wavelength range of 280 – 900 nm, and their contribution to the spectral radiation energy density depends on the discharge region and pressure. The emission bands of the first positive nitrogen system give the red color of the ionization waves, however, the highest intensities under these conditions are recorded on the lines of the second positive and first negative nitrogen systems. It is shown that when the pressure decreases to 0.04 Torr or less, the spectrum and color of the streamer discharge, while maintaining the amplitude of the voltage pulses, changes significantly. New lines and bands appear in it, including intense lines of atomic hydrogen, which is due to an increase in the reduced electric field strength, respectively, in the electron temperature. This leads to the dissociation of molecular gases that are part of the air, as well as those adsorbed by the chamber walls.
Уширение и сдвиг вращательных линий оксида углерода в широком диапазоне температур: расчеты в рамках классической ударной теории для CO-He
Authors: Иванов С.В.
Published: December 2022

The classical impact theory of Gordon is used to calculate half-widths and shifts of spectral lines of the pure rotational band of 12C16O isotopologue broadened by He. Two rotational transitions are examined: J=0J=1 and J=1J=2 in the wide temperature range from 1.3 to 600 K. The main purpose of this work is the study of the validity limits of classical impact theory at low temperatures. Dynamical calculations were performed on the accurate CO-He ab initio potential energy surface. The results of calculations are in good agreement with experimental data with the exception of very low temperatures. The contributions of collisions of different types (elastic, inelastic, quasibound complexes) are clearly examined in the classical picture frame. It is shown that the mismatches between classical theory and measurements are caused by the too high contribution of elastic collisions into broadening and shift in the present variant of theoretical model. The idea in the spirit of the Weisskopf theory is applied to try to diminish this contribution. The classical results are also compared with the results of fully quantum close coupling calculations made with using four CO-He interaction potentials. The roots of discrepancies at low temperatures as well as the virtues and the shortcomings of a classical approach are discussed.
Явление самозахвата в системе экситон-поляритонов при накачке нижней поляритонной ветви двумя лазерными импульсами с близкими частотами
Authors: Васильева О.Ф. , Зинган А.П. , Васильев В.В.
Published: December 2022

The dynamics of exciton-polariton states in a semiconductor microcavity is studied under pumping of the state corresponding to the lower polariton branch, taking into account single-mode and intermode elastic polariton-polariton interactions. In this case, pumping is carried out by two laser pulses with close frequencies. It is shown that at the initial phase difference equal to θ_0=π⁄2, the regime of quantum self-trapping of exciton-polaritons is observed. Periodic and aperiodic modes of evolution of a system of quasiparticles are obtained.
Влияние наночастиц карбида кремния на характеристики солнечных ячеек на основе дифталоцианина лютеция
Authors: Расмагин С.И.
Published: December 2022

Composites nanoparticles silicon carbide with lutetium diphthalocyanine were created. The size and shape nanoparticles silicon carbide, as well as their phase composition, were determined by electron microscopy. The absorption spectra of nanoparticles silicon carbide, a solution of lutetium diphthalocyanine, and a composite nanoparticles silicon carbide with lutetium diphthalocyanine were measured. Raman scattering spectra were obtained for nanoparticles silicon carbide. A comparative analysis of the absorption spectra of various samples was carried out. The effect of lutetium diphthalocyanine molecules on the optical properties nanoparticles silicon carbide was elucidated. The resulting composite of lutetium diphthalocyanine and nanoparticles silicon carbide was used as a sensitizer to create Gretzel cells. In the control Grätzel cell, lutetium diphthalocyanine was used as an absorber; in the working cell, lutetium diphthalocyanine was used in combination with nanoparticles silicon carbide. The open-circuit voltage and short-circuit current were measured under the same illumination of both Grätzel cells.
Экспериментальная реализация спектрального сенсора коэффициента преломления на основе отражательного интерферометра
Authors: Терентьев В.С. , Симонов В.А.
Published: December 2022

Experimental study of the sensor in the Kretschmann optical scheme, in which the sensitive element is a reflection interferometer (RI) for the oblique incidence of light, is presented for the first time. A brief theory of RI is given. The experimental sample was used to measure the refractive index of the residual atmosphere in a vacuum chamber during its pumping. The high Q-factor of the RI resonator made it possible to obtain a fairly narrow spectral maximum with a width of 1.7 nm. The spectral sensitivity of the sensor was 1000 nm / RIU and the quality parameter was 529 RIU–1, it was also demonstrated that resolution of 6.5 10-8 RIU can be achieved. Proposals for further improvement of the sensor characteristics are formulated.
Фотостабильность люминесценции квантовых точек Ag-=SUB=-2-=/SUB=-S и структур ядро/оболочка Ag-=SUB=-2-=/SUB=-S/SiO-=SUB=-2-=/SUB=-
Authors: Гревцева И.Г. , Овчинников О.В. , Смирнов М.С. , Кондратенко Т.С. , Дерепко В.Н. , Хуссейн А.М.Х. , Егоров Н.Е. , Возгорькова E.A.
Published: December 2022

The paper presents regularities that demonstrate the effect of passivating ligands formation of thioglycolic acid and L-cysteine (TGA, L-Cys) and dielectric shells (SiO2) on Ag2S nanocrystals interface on the photostability of their IR luminescence. Using FTIR absorption spectroscopy, the interaction manifestations of passivating ligands molecules of TGA and L-Cys with Ag2S nanocrystals, as well as the formation of SiO2 shell due to the process of replacing organic ligands with a silica ligand (MPTMS) ("ligand exchange"), were found. In the case of replacing TGA with MPTMS, an increase in the luminescence quantum yield of Ag2S quantum dots (QDs) and its resistance to long-term exposure to exciting radiation was found. In the case of replacing L-Cys with MPTMS, the formation of a fragmentary SiO2/L-Cys shell on Ag2S nanocrystals was observed due to the partial replacement of L-Cys with MPTMS, which contributes to the reverse photodegradation of Ag2S QDs luminescence of as a result of SiO2/L-Cys shell photodestruction.
Поправка к статье Усиление электрической площади импульса при отражениях от движущегося зеркала" Оптика и спектроскопия 130 (9), 1402--1404 (2022)
Authors: Розанов Н.Н.
Published: December 2022

It is indicated that sets of plane-parallel layers of linear materials do not reflect the zero-frequency component of the incident pulse and therefore cannot serve as mirrors for unipolar pulses. The amplification of the electric area is possible with Fresnel reflection from an unlimited medium with a refractive index lower than that of the medium in which the incident pulse propagates. The same is realized in the case of a thick layer of such a medium with the exclusion of the influence of reflection by its rear face due to the slope or roughness of the face. The movement of the boundary does not lead to an additional amplification of the electric area, since the increase in the peak amplitude of the wave upon reflection is compensated by a decrease in the pulse duration.
The Effectiveness of eHealth Interventions on Lifestyle Modification in Patients With Nonalcoholic Fatty Liver Disease: Systematic Review and Meta-analysis
Authors: Kwon Oh Young , Choi Jin-young , Jang Yeonsoo
Published: December 2022

Background

The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing in parallel with the epidemic of obesity and metabolic syndrome. Lifestyle modification is a crucial strategy for the treatment of NAFLD, which can lead to a reduction in liver fat with concomitant weight loss. The use of eHealth technologies is an effective approach to improve health outcomes in patients as they do not have any time and space limitations.

Objective

This study aimed to evaluate published eHealth intervention studies for the improvement of lifestyle modifications among patients with NAFLD and to provide recommendations for future studies.

Methods

We conducted a systematic review and meta-analysis. Five electronic databases (PubMed, Cochrane Central, CINAHL, Embase, and Web of Science) were searched for studies reporting the effect of lifestyle modification intervention using eHealth in patients with NAFLD published from inception to November 3, 2022. Study selection, data extraction, and quality assessment were performed by 3 researchers independently. The quality of included studies was assessed using the Cochrane risk of bias tool and the Risk of Bias Assessment Tool for Nonrandomized Studies.

Results

In total, 2688 records were identified, and 41 full-text articles were assessed. Seven studies were included in the systematic review. The participants of all interventions were 1257 individuals with NAFLD, and the mean age ranged from 38.3 to 57.9 years. The duration of the interventions was 3-24 months, and all interventions were categorized into 3 types: internet-based computers, telephones, and mobile apps. Of these, 4 studies were randomized controlled trials and were included in the meta-analysis: 3 studies for body weight and BMI and 4 studies for alanine aminotransferase (ALT) and aspartate aminotransferase (AST). According to the meta-analysis, clear improvements in BMI (P=.02; 95% CI –1.01 to –0.10), AST (P=.02; 95% CI –1.22 to –0.13), and ALT (P=.01; 95% CI –1.28 to –0.15) were observed in the eHealth intervention as compared with the control groups.

Conclusions

Lifestyle modification interventions using eHealth technologies are significantly effective for BMI, AST, and ALT in patients with NAFLD. Future research should conduct interventions with larger sample sizes and evaluate whether these interventions have sustained benefits, and how we can make these eHealth methods most effective on a large scale.
Comparison of Methods for Estimating Temporal Topic Models From Primary Care Clinical Text Data: Retrospective Closed Cohort Study
Authors: Meaney Christopher , Escobar Michael , Stukel Therese A , Austin Peter C , Jaakkimainen Liisa
Published: December 2022

Background

Health care organizations are collecting increasing volumes of clinical text data. Topic models are a class of unsupervised machine learning algorithms for discovering latent thematic patterns in these large unstructured document collections.

Objective

We aimed to comparatively evaluate several methods for estimating temporal topic models using clinical notes obtained from primary care electronic medical records from Ontario, Canada.

Methods

We used a retrospective closed cohort design. The study spanned from January 01, 2011, through December 31, 2015, discretized into 20 quarterly periods. Patients were included in the study if they generated at least 1 primary care clinical note in each of the 20 quarterly periods. These patients represented a unique cohort of individuals engaging in high-frequency use of the primary care system. The following temporal topic modeling algorithms were fitted to the clinical note corpus: nonnegative matrix factorization, latent Dirichlet allocation, the structural topic model, and the BERTopic model.

Results

Temporal topic models consistently identified latent topical patterns in the clinical note corpus. The learned topical bases identified meaningful activities conducted by the primary health care system. Latent topics displaying near-constant temporal dynamics were consistently estimated across models (eg, pain, hypertension, diabetes, sleep, mood, anxiety, and depression). Several topics displayed predictable seasonal patterns over the study period (eg, respiratory disease and influenza immunization programs).

Conclusions

Nonnegative matrix factorization, latent Dirichlet allocation, structural topic model, and BERTopic are based on different underlying statistical frameworks (eg, linear algebra and optimization, Bayesian graphical models, and neural embeddings), require tuning unique hyperparameters (optimizers, priors, etc), and have distinct computational requirements (data structures, computational hardware, etc). Despite the heterogeneity in statistical methodology, the learned latent topical summarizations and their temporal evolution over the study period were consistently estimated. Temporal topic models represent an interesting class of models for characterizing and monitoring the primary health care system.
GIT complications after open heart surgery (Preprint)
Authors: Elfagieh Mohamed
Published: December 2022

BACKGROUND

There was not observational studies have reported correlations between GIT Complications after Open heart surgery. This meta-analysis was performed to investigate whether there is a correlation between GIT complications and Open-heart surgery

METHODS

Literature searches were performed in PubMed, Google, and the Cochrane Library from period August, 15, 2022 to October, 20, 2022. Studies that investigated the correlations between any GIT complications and Open-heart surgery were included. The pooled Odds ratio (ROs) with 95% confidence interval (CI) for GIT complications after open heart surgery was calculated by using RevMan 5.4.5

RESULTS

The eleven RCTs comprising 215,615 patients were included. Mainly types of GIT complications after open heart surgery in the studies were Isolated GIT Bleeding, Hiatus hernia, Jaundice, Dysphagia and paralytic ileus. ORs was 0.00(0.00-0.00); but the most significant GIT Complications after open heart surgery was Hiatus hernia ORs was (1.23 0.78, 1.95). the second significant GIT complications were Jaundice ORs was 0.05 (0.03- 0.08) and Dysphagia ORs was 0.15 (0.08-0.25

CONCLUSIONS

Correlation between GIT Complications and Open-heart surgery
Digital Application of Clinical Staging to Support Stratification in Youth Mental Health Services: Validity and Reliability Study (Preprint)
Authors: Chong Min K , Hickie Ian B , Cross Shane P , McKenna Sarah , Varidel Mathew , Capon William , Davenport Tracey A , LaMonica Haley M , Sawrikar Vilas , Guastella Adam , Naismith Sharon L , Scott Elizabeth M , Iorfino Frank
Published: December 2022

BACKGROUND

As the demand for youth mental health care continues to rise, managing wait times and reducing treatment delays are key challenges to delivering timely and quality care. Clinical staging is a heuristic model for youth mental health that can stratify care allocation according to individuals’ risk of illness progression. The application of staging has been traditionally limited to trained clinicians yet leveraging digital technologies to apply clinical staging could increase the scalability and usability of this model in services.

OBJECTIVE

The aim of this study was to validate a digital algorithm to accurately differentiate young people at lower and higher risk of developing mental disorders.

METHODS

We conducted a study with a cohort comprising 131 young people, aged between 16 and 25 years, who presented to youth mental health services in Australia between November 2018 and March 2021. Expert psychiatrists independently assigned clinical stages (either stage 1a or stage 1b+), which were then compared to the digital algorithm’s allocation based on a multidimensional self-report questionnaire.

RESULTS

Of the 131 participants, the mean age was 20.3 (SD 2.4) years, and 72% (94/131) of them were female. Ninety-one percent of clinical stage ratings were concordant between the digital algorithm and the experts’ ratings, with a substantial interrater agreement (κ=0.67; P<.001). The algorithm demonstrated an accuracy of 91% (95% CI 86%-95%; P=.03), a sensitivity of 80%, a specificity of 93%, and an F1-score of 73%. Of the concordant ratings, 16 young people were allocated to stage 1a, while 103 were assigned to stage 1b+. Among the 12 discordant cases, the digital algorithm allocated a lower stage (stage 1a) to 8 participants compared to the experts. These individuals had significantly milder symptoms of depression (P<.001) and anxiety (P<.001) compared to those with concordant stage 1b+ ratings.

CONCLUSIONS

This novel digital algorithm is sufficiently robust to be used as an adjunctive decision support tool to stratify care and assist with demand management in youth mental health services. This work could transform care pathways and expedite care allocation for those in the early stages of common anxiety and depressive disorders. Between 11% and 27% of young people seeking care may benefit from low-intensity, self-directed, or brief interventions. Findings from this study suggest the possibility of redirecting clinical capacity to focus on individuals in stage 1b+ for further assessment and intervention.

CLINICALTRIAL
Growth Performance of Silkworms (Tubifex sp.) Cultivated Using a Dry Substrate
Authors: Yazid Mhd , Djunaidah Iin Siti , Nurhudah Moch
Published: December 2022

Silkworms are one type of live food that has begun to be intensified in their cultivation activities in Indonesia. This study aimed to determine the effect of feeding/dried substrate in different doses on the growth performance of silkworms. The second aim was to determine the appropriate dose of dry substrate for silkworm cultivation. The study used a completely randomized design (CRD) with 4 treatments of dry media at a dose of 114 g/m2 (D10), 228 g/m2 (D20), and 324 g/m2 (D30) dan without media as a control (D0). With 3 replications for each treatment. A silkworm starter was obtained from cultivation for 30 days. The research was conducted at Warung Benih Farm in Depok for 33 days. Data were analyzed using Analysis of Variance (ANOVA) and Duncan's further test with a confidence level of 0.05. The results showed that absolute weight growth, population growth, and the best productivity were obtained in the treatment of substrate addition with a dose of 324 g/m2 (D30) with an absolute biomass growth of 48.67 g, population growth of 59458 individuals, & the productivity of 0.556 g/m2 was/cycle. Most of the water quality observations are in the relatively optimal range.
PHARMACOLOGICAL EVALUATION OF CENTRAL ANALGESIC ACTIVITY OF ACACIA CATECHU BY HOT PLATE AND TAIL IMMERSION METHOD
Authors: AHIRWAR VIMLA , SAHU MANOJ KUMAR , VERMA LOKESH , BANWEER JITENDRA
Published: December 2022

Objective: The aim of the study was to evaluate the analgesic activity of Acacia catechu heartwood extracts on Swiss albino mice using hot plate and tail immersion method.
Methods: In this study, we used the aqueous and methanol extracts of heartwood of A. catechu to evaluate its analgesic activity. The aqueous extract was achieved by doubled distillation method and the methanol extract was achieved by cold maceration method. The mice were divided into four groups, each group consisting of six animals. Doses of 50, 100, and 300 mg/kg, p.o. of both the extracts of A. catechu were given to the mice. The responses were noted at 0, 15, 30, and 60 min.
Results: The results of both the methods were quick similar but differ based on extracts. The aqueous extract of A. catechu showed a much better yield of analgesic activity as compared to the methanol extract. The data were analyzed by graph using two-way analysis of variance, which showed the dose-dependent pain resistance.
Conclusion: The study confirmed the potency of A. catechu in pain management and points the future development to be conducted on it.
AN EPIDEMIOLOGICAL STUDY OF COVID-19 CASES ADMITTED IN A DEDICATED COVID HOSPITAL DURING SECOND WAVE OF CORONA PANDEMIC IN CENTRAL INDIA
Authors: VK SHARMA , KULSHRESTHA ALOK , PAL VISHNU
Published: December 2022

Objective: The objective of the study was to find out any peculiarities in the epidemiological and clinical profiles of COVID-19 cases, admitted in the hospital; which may be useful in management of health services in future.
Methods: Retrospective analysis of hospital records of COVID-19 cases admitted from March to May 2021 in our COVID hospital. A total of 1332 hospital case records were analyzed.
Results: Out of 1332 admitted COVID-19 cases, 50% were in age group 40–60 years. About 60% cases were male. Symptoms were fever (88.29%), sore throat (70.64%), breathlessness (58.84%), loss of smell (58.82%), pain in abdomen (53%), loss of taste (35.29%), and diarrhea (29.43%). Most cases had multiple symptoms. About 60% cases came in serious condition. About 65% cases needed intensive care unit admission. About 50% cases expired.
Conclusions: Only peculiarity noticed in clinical profile was loss of taste and sense of smell in few cases. Preponderance of males in the age group of 40–60 years and high mortality among the admitted cases was only peculiar epidemiological feature.
COVID-19 VACCINES: TARGETS, PRE-CLINICAL STUDIES, MECHANISMS OF ACTION, ADRS, AND ROLLOUT IN INDIA – A JOURNEY SO FAR
Authors: GOSAVI DEVESH D , N SHINDE CHETA
Published: December 2022

Coronavirus disease 2019 pandemic has been posing a serious threat to global public health till date. This calls for the development of effective treatment protocols, and most importantly, vaccines against the pathogen. Keeping these requirements in mind, we have pooled together, across broad domains of research, accounts on the leading efforts in the development of various vaccine candidates. It is apparent from our review of various studies that the efficacy of seemingly different techniques applied together, collaborative efforts coupled with rapid, timely dissemination of results has been the key behind successful vaccine development. The availability of curated databases has also been of great advantage. Furthermore, we have summarized in this article, the side effects of the various vaccines. We hope that this review will appeal the researchers and students as well as recent entrants in these research domains and the various studies described herein will inspire and be helpful for the advancement of public health.
ASSESSMENT OF VITAMIN D AND CALCIUM LEVELS IN WOMEN WITH PCOS: AN OBSERVATIONAL STUDY
Authors: ARORA SARU , KAUR PARNEET , GARG RAMA , KAUR MANINDER , RANI SANGEETA
Published: December 2022

Objectives: Polycystic ovarian syndrome (PCOS) is a prevalent endocrinal disorder in the women of reproductive age group. The present study aims to investigate the correlation between Vitamin D and calcium levels in PCOS subjects as well as to establish the correlation between body mass index, hyperandrogenism, and metabolic syndrome in various phenotypes of PCOS.
Methods: In the present prospective and observational study, a total of 80 patients diagnosed with PCOS were recruited. The recruited patients were divided in the following two groups - study group (60 women diagnosed with PCOS based on Rotterdam criteria); and control group (20 women without PCOS recruited from outpatient department and infertility clinics). Baseline characteristics, Vitamin D level, and serum calcium levels were measured in the two groups and then compared.
Results: The mean age of patients in both the groups was found to be comparable (study group: 26.45±5.95 years versus control group: 28.40±6.65 years; p=0.221). The difference of mean 25-Hydroxy Vitamin D3 level was found to be statistically highly significant (study group 14.71 [±9.12] ng/mL versus control group was 22.47 [±6.71] ng/mL; p=0.0008). The difference of mean serum calcium level was also found to be statistically highly significant (study group 9.14 [±0.50] mg/mL, and control group 9.74 [±0.45] mg/mL; p<0.0001).
Conclusion: Women with PCOS have a significantly lower serum 25-hydroxyvitamin D and calcium levels as compared to controls. There is need for routine Vitamin D3 and calcium screening in all patients of PCOS for better insight into its role in the syndrome. Screening and correction of Vitamin D3 and calcium deficiency may prevent PCOS and its manifestations.
CASE REPORT OF SYNOVIAL SARCOMA PRESENTING AS A THIGH SWELLING
Authors: KUMAR BINAY , PRASAD NIDHI
Published: December 2022

Synovial sarcoma (SS) is a rare tumor arising from the mesenchymal lining and commonly arising near proximity of joint. The tumor is difficult to diagnose initially or can be misdiagnosed due to its site and slow-growing potential. This is a malignant tumor with genetic predisposition and has a poor prognosis, if metastasizes to distant organs. The current study tries to describe the clinical, histopathological and immunochemistry findings of synovial sarcoma. A case of SSs presented in our institute for surgery and histopathological examination. Relevant history was taken retrospectively and consent of the patient was also taken. The treatment modality consists of wide excision surgery, chemotherapy, and radiotherapy. In this case, a 35 years old having tumor growth involving thigh area, the excised tumor was sent to our department for histopathological examination. On HPE, monophasic spindle cell tumor was diagnosed with differential diagnosis of SS or malignant peripheral nerve sheath tumor and immunohistochemistry staining was done for further confirmation.
DEMOGRAPHIC, CLINICO-PATHOLOGICAL PROFILE, AND IMMUNOHISTOCHEMISTRY STUDY IN FEMALE BREAST CANCER IN EASTERN INDIA: A HOSPITAL-BASED RETROSPECTIVE STUDY
Authors: DAS PABITRA , DAS SUNITA , JANA ARPAN , KUMAR DAS TAPAS
Published: December 2022

Objectives: Female breast cancer is the most common cancer in Worldwide. In India, locally advanced female breast cancer is more common (57%) and survival rate of female breast cancer is very poor because early age of disease onset, diagnosed in late stage, delayed initiation, and inadequate proper treatment. Few studies have been published in journals regarding clinico-pathological profile of breast cancer in India. However, there are limited data available in literature on demographic, clinico-pathological profile, and immunohistochemistry (IHC) study in female breast cancer in Eastern India.
Methods: Newly diagnosed, histopathology proved female breast cancer patients registered from January 2018 to June 2022 at department of radiotherapy was included in this study. This study was retrospective and primary data were collected from medical records of patients about their demographic, clinico-pathological, and IHC profile.
Results: The median age at diagnosis was 48 years. Incidence of female breast cancer was more in the age group of 41–50 years (39.5%) and most of the patients were in premenopausal group (59.2%). Locally advance disease, Stage III (50.7%) was more followed by Stage II (32.2%). Most common histopathology type was invasive ductal carcinoma not otherwise specified (90.8%) and Grade II (50%). Triple negative breast tumor was more common IHC type (32.9%).
Conclusions: In our study, locally advanced breast cancer was more common in premenopausal patients in urban area. Awareness regarding breast cancer among general population, early diagnosis and adequate proper treatment can reduce mortality of breast cancer.
Job Satisfaction and Quality of Work Life among Government Employees in the Municipality of Liloy Zamboanga Del Norte, Philippines
Authors: Licudan-Credo Grace , Naparota Leo Credo
Published: December 2022

This study aimed to assess the job satisfaction and quality of work life of the government employees in the Municipality of Liloy, Zamboanga del Norte, during the calendar year 2020. A quantitative descriptive-correlational research design was employed in this study. Using frequency counting and percent, weighted mean, standard deviation, Mann-Whitney U test, Kruskal-Wallis test, and Spearman Rank-Order Correlation, data were obtained from 170 employees of the Local Government Unit in Municipality of Liloy Zamboanga del Norte. The study found that the perceived level of employees' job satisfaction is strongly agreed upon and highly satisfied. Standard deviations less than 3.0 supported a high degree of homogeneity in their responses. In addition, the study discovered that the respondents' perceived quality of work life is strongly agreed upon and described to a very large extent. Standard deviations less than 3.0 supported a high degree of homogeneity in their responses. The study found no significant difference in the perceived level of employees' job satisfaction regarding age, sex, and level of education. Moreover, the study also found no significant difference in the perceived level of employees' quality work of life in terms of age, sex, and level of education. Furthermore, the study revealed a significant relationship between job satisfaction and employees' quality work of life in the Local Government Unit of Liloy. This indicates that job satisfaction is significantly related to quality work of life. Hence, management strategy and working environments would be enhanced to boost job satisfaction and employees' quality of work life.
Smart Hi-Fi Attendance using Palm Veins
Authors: J Gowri , M Jegan Prabhu , P Ranjith Krishna
Published: December 2022

Abstract: In our academics’ attendance plays a significant role where it is taken in the traditional way, which consumes a lot of time and manpower and the process is hectic. There comes the automated attendance system to solve these problems in the conventional way, but these automated systems also face some drawbacks such as processes time, accuracy, and contact attendance systems (fingerprint), which leads to the next generation of attendance systems, which overcomes all these issues with the help of palm vein and RFID (Radio-Frequency Identification) sensors. The palm vein sensor uses an infrared camera that captures the student's palm vein image when placed in front of the camera. After that, the image was extracted to reveal biological palm vein data that is unique for each human, even for identical twins as per research. The extracted biological features are then compared with previously stored features in the database. And to avoid cheating and malpractices, we are verifying the student again (two-step authentication) with the help of RFID cards when the student crosses the RFID transmitter If both conditions are met, then it allows the system to mark students with attendance.
Advanced Water Management System using Android
Authors: Oak Prasad , Korade Pratham , Parsewar Shravani , Inamdar Parul , Pandita Piyush , Sutar Purneya , Kurundkar Sangeeta
Published: December 2022

Abstract: In this fast-paced world people are not able to give attention to their daily work like the water management in their house, taking care of their pets etc. In many cities, corporation water comes after two to three days and it has one fixed timing of two hours only. At the same time you are out of the city or want to go out you can’t because someone should be present at the house at the same time to fill the water tanks. On that problem statement we design one system in which you can operate all the cocks, motor from anywhere through Android. There is one thing that in this fast world everything has got smarter so we are trying to give a very smart solution by the use of technology. Which is easy to manoeuvre and access. So that everyone will be benefited by it. We have used the existing technology to get the solution.
Applications of Fuzzy in the Field of Medicine
Authors: Gali Dr. Arun Kumar
Published: December 2022

Abstract: In this paper fuzzy sets have been applied to many fields in which uncertainty plays a key role. Medicine, often on the borderline between science and art, is an excellent exponent: vagueness, linguistic uncertainty, hesitation, measurement imprecision, natural diversity, subjectivity all these are prominently present in medical diagnosis.
Lehmer-4 Mean Labeling of Graphs
Authors: Shalini Dr P , Meena S. A.
Published: December 2022

Abstract: A graph G=(V,E) with p vertices and q edges is called Lehmer-4 mean graph, if it is possible to label verticesxЄV with distinct label g(x) from 2,4,6,8,.….…... 2p in such a way thatwhen eachedge e=uv islabeledwithg(e=uv)= (or) ,then the edge labels are distinct. In this case,g is called Lehmer-4 meanlabelingof G. Inthis paper, Lehmer-4 mean labeling have been introduced.
A Qualitative Study on Mother’s Perception of the 2019 revised Nuri Curriculum
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Shin Nam-ju
Published: December 2022

Objectives This study was conducted to examine in-depth the perception of the 2019 revised Nuri Curriculum for mothers with 5-years-old child who have experienced both the Nuri Curriculum and the 2019 revised Nuri Curriculum. Methods To this end, based on semi-structured interview questions, 6 mothers with children attending kindergartens in the metropolitan area were divided into three groups to fing out their perception and concerns about the 2019 revised Nuri Curriculum at the age of 4 and 5 compared to the Nuri Curriculum experienced at the age of 3. Results As a result of the study, first, the study participants were not aware of the revision of the Nuri Curriculum. As parental participation is important, discussions on parental education on the 2019 revised Nuri Curriculum will be needed. Second, it was positive about child-centered and play-centered, but ti was skeptical that all teachers could intervene and expand meaningful play for all children without a plan. It is believed that active discussion is needed to strengthen the teacher’s competency. Third, they were concerned about the increase in preference for private education and private elementary school due to greater concerns about insufficient preparation for elementary school entrance due to the play-centered 2019 revised Nuri Curriculum. Specific discussions will be needed to resolve parents’ anxiety about adapting to elementary school. Conclusions Therefore, this study is meaningful in that it provides basic data for establishing a social support system to identify and supplement various problems following the implementation of the 2019 revised Nuri Curriculum when the revised Nuri Curriculum was implemented for two years.
Analysis of Korean Research Trends on Career Counseling Using Keyword Network Analysis (2015~2022)
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, SHIN Jurang
Published: December 2022

Objectives The main words of the research on career counseling were extracted and analyzed, and various variables of career counseling were derived, and the research trends of career counseling were identified, and implications were provided for future research. Methods Among the papers published in the journals published in Korea, 176 papers with ‘career counseling’ as the main theme were collected and 810 main words were derived. The word refinement was performed using the Textom program, and the key keywords were identified through TF, TF-IDF, and N-gram of the Textom program, and analyzed and visualized them. In addition, the importance and influence of each topic were confirmed and analyzed by using the topic modeling analysis, and the results were visualized. Results First, it maintained its 20th paper from 2015 to 2019, then reduced to its 10th paper in 2020. Second, 176 papers were published in 71 journals, and career counseling was studied in various fields such as counseling, career education, and psychology. Third, as a result of examining the frequency of the major keywords of research related to career counseling, it was found that ‘career’, ‘counseling’, ‘group’, ‘group’, ‘education’, ‘decision’, ‘admission’, ‘program’, ‘analysis’, ‘teacher’ were in order. Fourth, the TF-IDF weight analysis results showed that it was almost similar to the ranking of the frequency of appearance. The keywords with relatively high weight were identified as ‘career’, ‘admission’, ‘education’, and ‘group’. Fifth, N-gram analysis confirmed the correlation between the key keywords. It was confirmed that counseling, decision, admission, group, education, identity, preparation, and search appeared in order of keywords that are highly related to career counseling keywords. Sixth, the degree of connection centrality expressed in the network was in the order of ‘career’, ‘counseling’, ‘group’, and ‘education’. Seventh, in the topic modeling analysis, the words such as ‘career’, ‘counseling’, ‘education’ were the main words that constitute the group. Conclusions Based on the results of keyword network analysis of the studies that used domestic career counseling as a variable, various variables for career counseling were derived and the direction of follow-up research was suggested based on this.
Comparison of Proof Characteristics of Mathematics Gifted Students and General Students in Algebra
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Hong Young Suk , Son Hong Chan
Published: December 2022

Objectives The purpose of this study was to obtain educational implications for proof guidance by examining the recognition of proof types and the actual proof process using algebra questions for first-year high school math gifted students and general students who learned proof in the 2015 revised curriculum. Methods A questionnaire was provided to 10 gifted students from science high schools located in middle and small cities and 20 general high school students. We investigate the preference for the proof type. In addition, after comparing the type of proof that appeared in the actual proof process and the type of proof that they preferred, the satisfaction level was investigated, and the result was analyzed. Results Gifted students showed a higher rate of preference for deductive proof in algebra questions than general students. Gifted students with the perception that they prefer deductive proof types performed deductive proofs with sophisticated algebraic expressions even in actual proofs, and showed high satisfaction with their proofs. On the other hand, the type of empirical proof (40%) was investigated in recognition of the type of proof preferred by general students. They frequently failed to perform their preferred deductive proof, and in these cases, they expressed dissatisfaction with their proof for reasons such as ‘not showing generality of proof’ and ‘unable to use mathematical characters and symbols’. In addition, the preferred proof type and the actual proof type did not match. Conclusions It was found that step-by-step proof guidance was needed to provide appropriate proof tasks to students with excellent proof ability, and to progress to the level of deductive proof through idea generation and understanding such as empirical proof if not.