bluuebunny/crossref_metadata_2025 huggingface dataset:
A PROPAGAÇÃO DO ERRO DO pKa DA ÁGUA NOS LIVROS DE QUÍMICA ORGÂNICA
Authors: Antonelli Leonardo , De Paula Rodrigo , Cunha Silvio
Published: September 2023

THE PROPAGATION OF THE ERROR IN THE pKa OF WATER IN ORGANIC CHEMISTRY TEXTBOOKS. In organic chemistry, the pKa is a property used to compare the acidity behavior for many substances, and to locate the position of equilibria in acid-base reactions and to provide information about structure and reactivity. Evidence in the literature shows that the values of pKa for water and hydronium ion, commonly cited in organic chemistry textbooks, are incorrect. The values of 15.74 for H2O and −1.74 for H3O+ are due to a propagated misconception in the equilibrium calculations while the correct values are 14.0 for H2O and 0.0 for H3O+. This subtle difference of 1.74 units on the pKa scale between both values reflects an error greater than 55 times in the level of acidity for these chemical species. An immediate correction of these values is necessary for the adequate teaching of organic chemistry. A literature search was conducted on the most used organic chemistry books in graduate and undergraduate courses in Brazil, revealing that almost all values cited were inadequate. The textbook Chemistry of Organic Compounds, 3rd edition (1965), by Carl Robert Noller is suggested as possible source of this misinformation in organic chemistry textbooks.
ESPECTROSCOPIA DE FLUORESCÊNCIA: DOS FUNDAMENTOS À INFLUÊNCIA DOS PARÂMETROS INSTRUMENTAIS PARA ANÁLISES DE CORANTES ORGÂNICOS E NANOPARTÍCULAS INORGÂNICAS
Authors: Mourão Rafael , Vale Brener , Fonseca André , Carvalho Thaís , Schiavon Marco
Published: September 2023

FLUORESCENCE SPECTROSCOPY: FROM FUNDAMENTALS TO THE INFLUENCE OF INSTRUMENTAL PARAMETERS FOR ANALYSIS OF ORGANIC DYES AND INORGANIC NANOPARTICLES. Fluorescence spectroscopy is an extremely sensitive analytical technique that has been widely used to elucidate problems that require low detection limits. Although fluorescence spectroscopy is widespread in industry and academia, there is a lack of teaching materials demonstrating its basic principles, as well as the influence of instrumental parameters involved in the technique, which limit its correct use and the full potential of it. For this reason, this work aims to explore the principles of fluorescence spectroscopy and correlate them in function of different instrumental variables to carry out a fluorescence experiment. The spectrofluorometer parameters such as the excitation wavelength, excitation and emission slits, step, integration time, detection geometry as well as concentration of the samples were varied to illustrate how the best resulting spectra can be registered free of artifacts. To do so, two organic dyes with structured vibronic bands (pyrene) and another with unstructured bands (rhodamine 6G) were used. Another study carried out involved the use of 3D spectra, excitation/emission spectra, of cadmium telluride (CdTe) quantum dots. In this case, it was possible to show the excitation spectrum of nanomaterials, collecting emissions at different wavelengths, as well as analyzing the particle size distribution.
Data-driven modeling of municipal water system responses to hydroclimate extremes
Authors: Johnson Ryan , Burian Steven John , Oroza Carlos Anthony , Halgren James , Irons Trevor , Aziz Danyal , Hassan Daniyal , Li Jiada , Hansen Carly , Kirkham Tracie , Stewart Jesse , Briefer Laura
Published: September 2023

Sustainable western US municipal water system (MWS) management depends on quantifying the impacts of supply and demand dynamics on system infrastructure reliability and vulnerability. Systems modeling can replicate the interactions but extensive parameterization, high complexity, and long development cycles present barriers to widespread adoption. To address these challenges, we develop the Machine Learning Water Systems Model (ML-WSM) – a novel application of data-driven modeling for MWS management. We apply the ML-WSM framework to the Salt Lake City, Utah water system, where we benchmark prediction performance on the seasonal response of reservoir levels, groundwater withdrawal, and imported water requests to climate anomalies at a daily resolution against an existing systems model. The ML-WSM accurately predicts the seasonal dynamics of all components; especially during supply-limiting conditions (KGE > 0.88, PBias < ±3%). Extreme wet conditions challenged model skill but the ML-WSM communicated the appropriate seasonal trends and relationships to component thresholds (e.g., reservoir dead pool). The model correctly classified nearly all instances of vulnerability (83%) and peak severity (100%), encouraging its use as a guidance tool that complements systems models for evaluating the influences of climate on MWS performance.
Ecosystem governance of rural water ecosystem services under sustainable utilization
Authors: Yang Shujie
Published: September 2023

Water resources not only threaten the physical health of rural residents but also affect their drinking water needs, causing certain damage to the rural water ecosystem services (WES) and threatening the coordinated development of the natural ecological environment. In response to issues such as outdated personnel awareness, severe WES waste, and low resource utilization in current WES governance, this article optimized and monitored relevant governance methods for the rural WES environment to improve the sustainable utilization of WES. This article analyzed the main types of WES and studied the monitoring and governance methods of WES governance. This article used the projection pursuit model to evaluate the governance methods of WES comprehensively and proposed corresponding strategies for optimal utilization to improve the utilization rate of WES. The WES utilization rate and rural sewage treatment capacity after optimization measures were higher than those before optimization measures. The utilization rate of WES after the optimization strategy was 15.4% higher than before, and the rural pollution treatment capacity was 17.8% higher than before the optimization strategy. Improving investment in water pollution technology and environmental infrastructure in rural areas is important and positive in improving rural WES governance and sustainable utilization.
Removal of microfiber and surfactants from household laundry washing effluents by powdered activated carbon: kinetics and isotherm studies
Authors: Cetinkaya Atesci Zuhal , Inan Hatice
Published: September 2023

Domestic laundry wastewater discharge contributes significantly to the presence of microfiber and surfactant pollutants in aquatic ecosystems, which have detrimental and toxic effects on humans and the environment. Investigating the efficacy of powdered activated carbon (PAC) in removing micro-/nanofibers with or without surfactant from household laundry effluent is the purpose of the current research. To simulate real-world scenarios, PAC adsorption kinetics and isotherms in laundry effluents under controlled conditions were studied. These studies showed that the kinetics obeyed a pseudo-second-order process and the isotherms varied between Langmuir and Freundlich models depending on the water types. In the results of experiments using distilled water and tap water, it was observed that the adsorption capacity was higher in tap water. When the adsorption of 0.1 μm filtered synthetic garments, detergent, and tap water was compared with the adsorption of the raw sample, it was observed that the adsorption capacity of the 0.1 μm filtered version was higher. Even though this study is preliminary, the results indicate that PAC has the capacity to serve as a viable approach for mitigating micro-/nanoplastic and surfactant contamination from laundry wastewater, thereby offering valuable guidance for advancing eco-friendly laundry techniques.
Catalytic polymerization of bisphenol A using a horseradish peroxidase immobilized microporous membrane reactor
Authors: Li Haitao , Guo Linfeng , Li Yingying , Chen Min , Bai Chunlu , Song Aolei , Cheng Linxiu , Chen Xueli , Chen Yonglin
Published: September 2023

Bisphenol A (BPA) is one of the most widely used chemical products, which is discharged into rivers and oceans, posing great hazards to organisms such as reproductive toxicity, hormone imbalance and cardiopathy induction. With the expansion harm of BPA, people have paid more attention to the environmental effects. In this paper, the degradation of BPA from the synthetic wastewater using the immobilization of horseradish peroxidase membrane reactor (HPR) was investigated. The immobilized HRP microporous membrane was prepared by the porous calcium alginate method. In addition, the reuse of the immobilized HPR membrane and the measurement of membrane flux showed that the membrane has good activity and stability. Finally, the experimental parameters including reaction time, pH, the concentration of BPA and the dosage of H2O2 were optimized to remove the BPA, and about 78% degradation efficiency of BPA was achieved at the optimal condition as follows: H2O2 to BPA molar ratio of 1.50 with an initial BPA concentration of 0.1 mol/L, the HPR dosage of 3.84 u/mL, the initial solution pH of 7.0, a temperature of 20 °C and a contact time of 10 min.
A busca da RevUergs pela indexação em bases e diretórios
Authors: De Castro Biane , Izoton Monique , Semensatto Simone
Published: September 2023

A temática deste Editorial se reserva a comentar sobre a busca pela indexação. Uma das preocupações dos periódicos científicos no meio acadêmico é alcançar o maior número de leitores e, consequentemente, de citações. Em âmbito mundial, duas grandes bases de dados realizam métricas para monitorar o impacto das revistas na comunidade acadêmica. Ainda em relação à indexação, houve a inclusão da RevUergs no Miguilim, que é o Diretório das revistas científicas eletrônicas brasileiras do Instituto Brasileiro de Informação em Ciência e Tecnologia (IBICT). Participam deste diretório, em sua maioria, as instituições de ensino superior públicas de diversos estados, tanto da esfera federal quanto da estadual. O objetivo é reunir as informações essenciais sobre as revistas editadas e publicadas no Brasil. Existem diretórios que são fontes confiáveis e que promovem a divulgação de aspectos sobre a política editorial (copyright) das revistas científicas. Entre eles podemos citar: Sherpa Romeo, Dulcinea e Diadorim. A RevUergs foi inicialmente indexada no Diadorim, que é um serviço de responsabilidade do IBICT, e agora estamos também no Sherpa Romeo. De  acordo com Costa e Alves (2019), o Sherpa Romeo foi criado  como parte do projeto Securing a Hybrid Environment for Research Preservation and Access e apresenta e agrega as políticas de acesso aberto para editores e periódicos científicos de diversos países. Tais políticas são importantes para observar as formas de acesso e de armazenamento dos artigos para autores e editores, bem como para uso (catalogação) em repositórios temáticos e/ou institucionais.
Study for Some Eccentricity-based Topological Indices of Second Type of
Dominating David-derived Network
Authors: Liu Jia-Bao , Ali Haidar , Ali Didar Abdulkhaleq , Umer Ayesha , Ali Parvez , Kirmani Syed Ajaz K.
Published: September 2023

Background:

Dominating David-derived networks are widely studied due to their
fractal nature, with applications in topology, chemistry, and computer sciences. The use of
molecular structure descriptors is a standard procedure that is used to correlate the biological
activity of molecules with their chemical structures, which can be useful in the field of
pharmacology.

Objective:

This article's goal is to develop analytically closed computing formulas for eccentricitybased
descriptors of the second type of dominating David-derived network. Thermodynamic
characteristics, physicochemical properties, and chemical and biological activities of chemical
graphs are just a few of the many properties that may be determined using these computation
formulas.

Methods:

Vertex sets were initially divided according to their degrees, eccentricities, and
cardinalities of occurrence. The eccentricity-based indices are then computed using some
combinatorics and these partitions.

Results:

Total eccentricity, average eccentricity, and the Zagreb index are distance-based
topological indices utilized in this study for the second type of dominating David-derived network,
denoted as D2(m).

Conclusion:

These calculations will assist the readers in estimating the fractal and difficult-tohandle
thermodynamic and physicochemical aspects of chemical structure. Apart from
configuration and impact resistance, the D2(m) design has been used for fundamental reasons in a
variety of technical and scientific advancements.
Scale-up of Sodium Persulfate Mediated, Nitroxide Catalyzed Oxidative
Functionalization Reactions
Authors: Doherty Katrina E. , Sandoval Arturo L. , Politano Fabrizio , Witko Mason L. , Schroeder Chelsea M. , Brydon William P. , Wadey Geoffrey P. , Ohlhorst Kristiane K. , Leadbeater Nicholas E.
Published: September 2023

Background:

Oxidation is a valuable tool in preparative organic chemistry. Oxoam-monium salts and nitroxides have proven valuable as reagents and catalysts in this endeavor.

Objective:

The objective of this study is to scale up the oxidative amidation, ester formation, and nitrile formation using nitroxide as an organocatalyst.

Methods:

Oxidative functionalization reactions were scaled from the 1 mmol to the 1 mole level. Sodium persulfate was used as the primary oxidant, and a nitroxide was employed as a catalyst. The products of the reactions were isolated in analytically pure form by extraction with no need for column chromatography.

Results:

The oxidative amidation and esterification of aldehydes can be scaled up from 1 mmol to 1 mole effectively, with comparable product yields being obtained at each increment. This work shows that conditions developed on a small scale can be transferred to a larger scale without reop-timization. The oxidative functionalization of aldehydes to prepare nitriles is not amenable to direct scale-up due to the concomitant formation of significant quantities of the corresponding carboxylic acid, thereby compromising the product yield.

Conclusion:

Two of the three oxidative transformations studied here can be scaled up successfully from the 1 mmol to the 1 mole level.
An 88-year-old Man with Rare Giant Liposarcoma of the Scrotum
Authors: Zhou Lili , Zhang Caixiang , Xu Yongde , Wei Xuan , Wang Zhenchang
Published: September 2023

Background:

Liposarcoma (LPS) is a malignant mesenchymal tumor that mostly occurs in the extremities and retroperitoneum and rarely in the scrotum.

Case Presentation:

In this case report, we introduced a patient who was diagnosed with LPS in the scrotum. In his right scrotum, we found a large soft tissue mass, including fat and calcification.

Conclusion:

We reviewed the clinical, pathological and computed tomography (CT) features of patients diagnosed with LPS of the scrotum to help improve the understanding of the disease and the accuracy of diagnosis.
Esophageal Hematoma Mimicking Esophageal Varices after Chewing Betel Nut:
A Case Report
Authors: Shi Yan , Wu Qian-neng , Zhang Fu-long , Chen Shu-rong , Zhou Dan , Zhu Yuan-dong
Published: September 2023

Background:

Betel nut chewing is very common in Southeast Asia and other tropical countries. Much clinical evidence suggests that chewing betel nut has pro-inflammatory and carcinogenic effects, but there are few clinical reports of acute toxicity caused by it, especially involving esophageal damage.

Case presentation:

We presented a case of a 72-year-old female who was admitted to our hospital for chest pain and hematemesis within several minutes after chewing betel nut. Gastroscopy showed two longitudinal ridge-like mucosal eminences in the esophagus located 20 cm from the incisors down to the gastric cardia, which was similar to varices. At last, a CT scan showed concentric-circle thickening of the esophagus wall, suggesting hematomas. Our treatment included fasting, inhibiting gastric acid and maintaining blood volume. After one week of medical treatment, rechecked gastroscopy showed that esophageal hematomas were gradually absorbed, with the formation of multiple shallow ulcers.

Conclusions:

The acute toxicity of chewing betel nut can be easily overlooked. Patients who experience chest pain or hematemesis after chewing betel nut products,especially those who take aspirin at the same time, need to be alert to esophageal hematoma.
A Critical Appraisal on Controlled Drugs: Classification, Global Regulatory
Provisions, and Distribution
Authors: Ranjan Animesh , Gaurav  , Sandeep Patil Niraj , Shekhar Shashi Shivendu , Singh Dilpreet
Published: September 2023

Controlled drugs, characterized by their potential for abuse and addiction, require stringent regulation to ensure their safe and appropriate use. This critical appraisal provides a scientifically sound examination of the classification of controlled drugs, global regulatory provisions governing their use, and the challenges associated with their distribution. Due to poor regulation, it is anticipated that 80% of the world’s population will have insufficient access to these painkillers. India needs a more robust enforcement mechanism, with the main goal of ensuring that medications are accessible to patients in need while preventing abuse and trafficking. As a result, studying the topic of “A Regulatory Need of Controlled Drugs” is important, serious, and indispensable. As a result, the authors of the present review discussed numerous regulatory authorities, drug enforcement agencies, and the storage and distribution of banned substances in India. In light of the findings, this review suggests future directions and recommendations. Strengthening international collaboration and information sharing can facilitate the development of more effective regulatory measures. Improved tracking and monitoring systems, incorporating technological advancements, hold promise for enhancing control over the distribution of controlled drugs.
Clinical Considerations in Working with Children and
Adolescents of Color: Past, Present, and Future
Authors: Yuen Eunice , Daily Susan , Sadhu Julie , Baek Janet , Shapiro Gabrielle , Pfeffer Cynthia , Dowben Jonathan , Jackson Kamilah , Sarvet Barry , Stubbe Dorothy
Published: September 2023

Background:

Systemic racism and health inequality for Children and
Adolescents of Color (CAoC) and their families need to be acknowledged and
addressed in the provision of mental health treatment by child and adolescent
psychiatrists. The lack of parity for behavioral health drives the lack of integration of
“mental” health with overall health and the lack of funding, policy, planning, and
practices to support the social and emotional health of children and their families.
Additionally, the unequal treatment faced by Black, Indigenous, and People of Color
(BIPOC) children and their families further impacts their overall health and mental
health outcomes. Implicit biases, conscious and unconscious, influence clinical
judgments, lead to errors in diagnostic and treatment decisions and impair child and
adolescent psychiatrists’ ability to fully partner with families to treat, advocate for,
and improve the clinical and life trajectories of this diverse group of young people
and families that child and adolescent psychiatrists are called to serve.

Methods:

Using a case vignette, this paper discusses historical examples showing
how child and adolescent psychiatrists’ implicit bias may manifest when working
with CAoC. Medical training and clinical practice have paid scant attention to the
broader impacts of systemic racism and inequities in healthcare until recent years.

Discussion:

This article provides clinical recommendations for clinicians to navigate
these factors through trauma-centered and patient-centered care. Viewing through the
lens of intergenerational racial trauma and acknowledging one’s own bias, clinicians
can better help and support CAoC as they strive toward a brighter future.
HCI Learning From Cognitive Web
Authors: Singh Kaswan Kuldeep , Baliyan Anupam , Dhatterwal Jagjit Singh , Kaiwartya Om Prakash
Published: September 2023

A cognitive framework is suggested in this article to monitor learning
processes based on the combination of human-computer interaction. The observation is
founded on the interaction of elements between humans and the computer. The
adaptive architecture of cognitive learning is introduced for interaction between
humans and machines. The authors have also chosen a topology tree as the hierarchical
model of a low-dimensional educational space to perform online observations. In
addition, the methodology for the BSM (coupling-manifold brain human cognitive
scenario) is provided for the coupling morphism. It proposes that things be observed in
a mental or learning diverse way. Finally, this chapter suggests developing new tools
and implementing different functionalities integrating intelligent data analysis
techniques. An area that still needs further work is the cognitive area, particularly
towards helping build more accurate mental model.
Big Data Decision Computations To HCI
Authors: Singh Kaswan Kuldeep , Baliyan Anupam , Dhatterwal Jagjit Singh , Kaiwartya Om Prakash
Published: September 2023

This chapter deals with CRT calculations. The idea of experimenting,
optimization, simulation, data mining, and large data is explained in plain language
before introducing the intelligent architectures, which turn data into CRT system
judgments. Most of the architecture may be employed in any circumstance outside the
CRT. However, increasing this architecture to the ability of CRT provides unparalleled
computing skills for both offline and real-time decision-making. In this chapter,
augmenting these architectures with CRT capabilities offers unprecedented
computational capabilities for offline and real-time decision-making situations equally.
Relationship Between Big Data, NLP, And Cognitive Computing
Authors: Singh Kaswan Kuldeep , Baliyan Anupam , Dhatterwal Jagjit Singh , Kaiwartya Om Prakash
Published: September 2023

The capacity to get insights and operations from data has not significantly
altered with tremendous technological advances over the previous 30 years.
Applications are generally built to fulfill default responsibilities or automate tasks;
thus, the designer must prepare and write the logic for every situation. Computers are
quicker and less expensive but not significantly more intelligent. Naturally, people are
not more brilliant than they were 30 years before. For people and robots, this is going
to change. A new generation of information technology emerges, starting with the
automation technology from the previous computer model to offer a collaborative
discovery platform. These technologies' initial wave has already increased human
knowledge in several disciplines. These computers may draw meaning from volumes
of natural language text as collaborators or collaborators for their human users and
create and assess hypotheses in minutes based on analysing more significant facts than
a person would absorb in a lifetime. That's the potentil of artificial intelligence. This
chapter discusses a relationship between big data, NLP, and Cognitive Systems, voice
in NLP component and performing the related tasks. This chapter contrasts
unstructured data in written material, video, and images, designed for human
consumption and interpretation and also explains big data's role in creating cognitive
computing systems.
Representation of Knowledge in Taxonomies and Ontologies and their Application in Advance Analysis to Cognitive Computing
Authors: Singh Kaswan Kuldeep , Baliyan Anupam , Dhatterwal Jagjit Singh , Kaiwartya Om Prakash
Published: September 2023

This chapter focuses on how ontologies and semantic web technology can be
used in artificial intelligence or systems engineering. Technological trends imply that
future digital technology approaches and tools will use AI and ML technology. Logic based reasoning and semantic modeling assist in classification, customization, and
relationship detection but struggle to describe how decisions are made. Knowledge
acquisition plays a vital role in using this form of AI. Ontologies are methods for mode
modeling of reasoning domains required for digital fields instantiated in Digital System
Models (DSM). They grow as digital twins and evolve with the physical instantiations
of a DSM over time. Semantic innovations and ontologies codify knowledge of
systems engineering as a prerequisite for reasoning using interoperable ontologies. This
chapter explores the technologies behind advanced analytics and how they can be
leveraged in a knowledge-driven cognitive environment. Advanced analytics help
gaining deeper insights and predict outcomes more accurately and insightfully.
Data Visualisation and Data Analytics in HCI
Authors: Singh Kaswan Kuldeep , Baliyan Anupam , Dhatterwal Jagjit Singh , Kaiwartya Om Prakash
Published: September 2023

This chapter uses Light Detection and Ranging (LIDAR) technology field
data to assess efficient terrain visualization. There are two algorithms for detailed
computer rendering. The test results for the productivity of the two these algorithms or
techniques are presented in the subsequent sections. In visual-spatial perception, the
assessment of the results is ultimately examined. In this chapter, the model then uses
the information to select the optimal level of details (LOD) to prevent visible changes
in representation. The relationship between computer processing power and mental
representation is critical for understanding these cognitive processes.
Regulatory Aspects of Nanomaterials: Current and Future Perspective
Authors: Raval Mihir , Chavda Pratibha , Patel Priya
Published: September 2023

Nanotechnology and its applications have been a rapidly growing area of
research in the previous two decades. In the domain of pharmaceutical research,
nanotechnology is applied in the study and preparation of nano-size range materials
ranging from 1-100nm. Nanoparticulate medications or nano drug delivery systems are
not a novel concept, but they are a rapidly evolving nanoscience. In nanomedicine,
nanoscale materials are used to develop diagnostic tools or to deliver active substances
to a particular place in a consistent and controlled manner. Nanoparticles have groveled
in many different forms, including liposomes, niosomes, solid lipid nanoparticles,
emulsions, suspension nanocrystals, micelles, and dendrimers. When compared to pure
drugs or other conventional formulations, these all have improved medication efficacy
or therapeutic effect. Nanoparticles are being employed in a variety of fields, including
cosmetics. However, as nanotechnology progressed, numerous controversies arise
concerning nanoparticles. Consumer safety, as well as environmental repercussions,
must be regulated. Nanotechnology has life-changing applications, yet nanoparticle
regulation has been inconsistent and insufficient. Failure in biotechnology regulation in
recent years has resulted in several negative consequences for the environment and
human health. This article aims to raise knowledge about the importance of regulatory
frameworks for nanotechnology and nanoparticles.
Optimization of Various Costs in Inventory Management using Neural Networks
Authors: Sharma Prerna , Singh Bhim
Published: September 2023

The process of maintaining the right quantity of inventory to meet demand,
minimising logistics costs, and avoiding frequent inventory problems, including reserve
outs, overstocking, and backorders is known as inventory optimisation. One has a finite
capacity and is referred to as an owned warehouse (OW), which is located near the
market, while the other has an endless capacity and is referred to as a rented warehouse
(RW), which is located away from the market. Here, lowering the overall cost is the
goal. Neural networks are employed in these works to either maximise or minimise
cost. The findings produced from the neural networks are compared with a
mathematical model and neural networks. Findings indicate that neural networks
outperformed both conventional mathematical models and neural networks in terms of
optimising the outcomes. The best way to understand supervised machine learning
algorithms like neural networks is in the context of function approximation. The
benefits and drawbacks of the two-warehouse approach compared to the single
warehouse plan will also be covered. We investigate cost optimisation using neural
networks in this chapter, and the outcomes will also be compared using the same.
Novel Natural Compounds for Hepatocellular Carcinoma Treatment
Authors: ÖNER Çağrı , ÇOLAK Emine
Published: September 2023

Due to the increase in cancer cases nowadays, an increase in studies related
to treatment has been observed. Although many natural or synthetic compounds have
been described as therapeutic today, the effects of these treatments are seen in both
healthy and cancer cells. In order to reduce these undesirable effects seen in
chemotherapy and radiotherapy, alternative treatments that have less effect on healthy
cells or alternative attitudes that will allow the minimum use of therapeutics in these
treatments continue to be investigated. In particular, such studies focus on natural
compounds with phenolic properties. This chapter focuses on the relationship between
coumarin derivatives, curcumin, Olea europaea leaf extract, and Cynara scolymus leaf
extract with hepatocellular carcinoma. Furthermore, the effect of these natural
compounds on the genetic hallmarks of various signalling pathways and important
cellular metabolism molecules of hepatocellular carcinoma are discussed.
Satisfacción laboral del directivo y posibles implicancias en la ejecución presupuestaria: caso universidades públicas de Perú
Authors: Arnao Rondán Raymundo Ildefonzo
Published: September 2023

Esta investigación se propuso conocer el nivel y principales características de la satisfacción laboral de los directivos de las universidades públicas de Perú, y del avance de ejecución presupuestaria de estas instituciones, así como la correlación existente entre esa satisfacción laboral y el indicado avance de ejecución. Para la medición de la satisfacción laboral se aplicó una encuesta a una muestra de directivos de áreas especializadas de la administración central de la institución (se excluyeron cargos electos), mediante un cuestionario generado en una experiencia piloto y con la correspondiente verificación estadística de su confiabilidad.

Reconociendo que existe una gran heterogeneidad entre las universidades púbicas en monto de presupuesto, número de trabajadores y número de estudiantes, entre otras dimensiones, se conformó cinco estratos, empleando como criterio de agrupamiento el presupuesto total y el presupuesto de proyectos del trienio 2017-2019, para cada caso. A través de estos grupos se demuestra el heterogéneo avance en la ejecución del presupuesto entre las universidades públicas, siendo más acentuado las diferencias en proyectos; asimismo, se evidencia el predominio de diversidad de niveles y características en cuanto a la satisfacción laboral de sus directivos.

Finalmente, teniendo como unidades de análisis a las universidades, se verificó la existencia de una correlación positiva moderada entre la satisfacción laboral y los avances de ejecución presupuestaria (tanto a nivel total como de proyectos). Lo cual implica que es moderadamente probable que una mayor satisfacción laboral esté acompañada de un mejor avance de ejecución presupuestaria.
Ciclos económicos en el Perú. Tres perspectivas
Authors: Erquizio Espinal Oscar Afredo
Published: September 2023

Los ciclos económicos pueden ser examinados desde: lo espacial (globales, nacionales y regionales); lo temporal (largo y corto plazo); los autores que identifican exhaustivamente los ciclos Kondratieff del Perú (Seminario, 2015), los ciclos Kondratieff globales (Grinin et al, 2016) y los ciclos económicos clásicos globales (Kose y Terrones, 2015). La propuesta es analizar los ciclos económicos del Perú desde dichas perspectivas reconociendo el aporte de Bruno Seminario en lo que se refiere a los ciclos de Kondratieff. Añadiendo la de los ciclos económicos clásicos, pues se considera que ella está ausente en el tratamiento histórico y contemporáneo del tema en el caso del Perú. Para lo cual: se revisa el campo de estudio de los ciclos económicos; se examina la: literatura acerca de los ciclos de Kondratieff globales, contextualizando así la propuesta de (Seminario, (2015) para el caso peruano; se identifican los años de: crisis financieras globales (Reinhardt y Rogoff, (2009) y recesiones globales (World Bank, 2020) y se anotan observaciones acerca de lo sucedido en el Perú en dichos años; se identifican los ciclos económicos clásicos del Perú 1950-2020, utilizando además de las nacionales, las cifras regionales de (Seminario, Zegarra y Palomino, (2019) y regionales-sectoriales del (Instituto Nacional de Estadística e Informática, 2021), lo que permite dimensionar las recesiones a escala nacional, sectorial y regional en el Perú, mediante los índices de difusión respectivos.
Ilustración de las técnicas econométricas: Análisis y predicción del sector industrial
Authors: Salinas Ortiz José
Published: September 2023

Este artículo describe y discute los conceptos fundamentales del Análisis Econométrico usando una aplicación concreta que permite ilustrar el uso adecuado de las técnicas econométricas a los estudiantes de econometría, y en general a las personas interesadas en usar estas técnicas. El periodo de estimación de la aplicación abarca 16 años, en el cual el autor usa las técnicas citadas para analizar el comportamiento del sector manufacturero. Para ilustrar los conceptos y uso de la econometría en la estimación y análisis se usa la técnica de “Pasos Sucesivos” que permite presentar los diferentes estadísticos que indican el grado de éxito alcanzado con cada una de las ecuaciones estimadas, y los principales problemas del análisis de regresión (multicolinealidad, autocorrelación). Además, se presentan criterios para elegir la mejor entre las ecuaciones estimadas. Finalmente, se enfatiza que el investigador debe complementar las técnicas econométricas con sus conocimientos teóricos y su experiencia o entendimientos del fenómeno que busca explicar.
CÉLULAS SOLARES CON ALTA EFICIENCIA BASADAS EN PELÍCULAS DE ÓXIDO DE TITANIO NANOCRYSTALINO SENSIBILIZADO
Authors: Gómez M. M. , Lu J. , Olsson E. , Hagfeldt A. , Granqvist C. G.
Published: September 2023

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UNA PRUEBA DE UNICIDAD RESPECTO DE LA SECUENCIA DE MULTIPLICADORES GENERADA POR EL MÉTODO LAGRANGEANO AUMENTADO
Authors: Rezza Espinoza Yna Consuelo
Published: September 2023

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ESTUDIO NUMÉRICO DE LA SOLUCIÓN PARA EL PROBLEMA DEL DIQUE
Authors: Mantilla Nuñez Irla , Roca Galindo Luis
Published: September 2023

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PREDICCIÓN DEL EQUILIBRIO DE FASES DEL SISTEMA ACETATO DE N-BUTILO-CICLOHEXANO A BAJAS PRESIONES
Authors: Pílco Nuñez Alex , Paucar Cuba Karin , Zavaleta Ortiz Jac
Published: September 2023

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Predicción de la densidad de gases naturales usando las ecuaciones de estado de Soave-Redlich-Kwong, Peng-Robinson y AGA8-DC92
Authors: Zavaleta Ortiz Jack , Pilco Nuñez Alex , Villanueva Guzmán Sergio
Published: September 2023

En este trabajo se han usado las ecuaciones de estado (EOS) de Soave-Redlich-Kwong(SRK), Peng-Robinson (PR) y AGA8-DC92 (AGA) en la predicción de la densidad para diferentes gases naturales. Se recomienda el uso de las ecuaciones de SRK y PR en el intervalo de 240 a 350K y de 1 a 8 MPa (SRK) y de 1 a 15 MPa (PR), por producir errores menores al 3%, lo que es válido para los 613 puntos experimentales que se tomaron de la literatura; tal situación es ventajosa por ser las ecuaciones de estado más faciles de manipular qe la ecuación AGA. Sin embargo, todos los cálculos realizados demuestran que la ecuación AGA es superior a las ecuaciones SRK y PR en todo el rango de presión y temperatura de los datos experimentales usados. Se ha desarrollado una herramienta computacional para el cálculo de la densidad (ρ) y factor de compresibilidad (Z), que incorpora una base de datos de ρ experimental para diferentes gases naturales.
Estimación de humedad de café pergamino utilizando un secador solar automatizado, mediante modelos matemáticos en Jaén-Perú
Authors: Quiñones Huatangari Lenin , Barzola Cárdenas Abner , Vásquez Ochoa Blanca , Pérez Guevara Iván , Díaz Torres Martín
Published: September 2023

El café es un producto muy consumido a nivel mundial, debido a que posee un poder estimulante y energizante. Además, el proceso de secado es un factor esencial que influye en la calidad final del producto, en este sentido, el objetivo del presente artículo fue estimar la humedad del café pergamino al emplear un secador solar automatizado, mediante modelos matemáticos. Los modelos empleados fueron del tipo regresión lineal múltiple y regresión no lineal, los mismos que fueron determinados con los softwares R y Curve Expert Professional respectivamente. Los datos necesarios para estimar dichos modelos, fueron recolectados en campo durante cinco días, la cual consistió en aplicar el secador solar automatizado en la parcela de un agricultor del centro poblado de las Naranjas, Jaén, Cajamarca, Perú cuya variedad fue Catimor. Se determinaron cinco modelos: Un modelo de regresión lineal múltiple y cuatro modelos no lineales con un coeficiente de correlación  mayor que 0,91. Sin embargo, el modelo empleado para describir la radiación solar en Grecia, es el que mejor describe el comportamiento de la humedad del grado de café pergamino en términos del tiempo de secado en el secador solar automatizado empleando los estadístico de bondad de ajuste.
MEDICIONES ESPECTRALES FOTOACÚSTICAS(PAS) DE PELÍCULAS SEMICONDUCTORAS DE SILICIO AMORFO
Authors: Fernández Chillcce Enver , Eyzaguirre Gorvenia Carmen , Valera Palacios Aníbal
Published: September 2023

En este trabajo se presenta el resultado de la caracterización fotoacústica (PAS) de películas finas de silicio amorfo mediante mediciones espectrales de transmisión y absorción. En base a muestras semiconductoras obtenidas por el método de descarga plasmática reactivo se obtienen los parámetros ópticos del material (índice de refracción y coeficientes de absorción) en un amplio rango espectral, en buena correspondencia con evaluaciones previas . Determinándose así finalmente la energía del cuasi gap (Tauc) y el modelo de bandas del semiconductor de a-Si:H.
The Opinions of Married Women Living in the Metropolitan Area of Turkey on the Family Planning Method they Use: A Qualitative Research
Authors: BİLGİÇ Fatma Şule , YILDIZ KARAAHMET Aysu
Published: September 2023

Objective: This research was conducted to examine the views of women on four different types of family planning they use.
Materials and Methods: The period of time for this qualitative study was January through February 2023. 33 Istanbul-based women made up the study's sample. In order to create the greatest possible diversity, the study's participants' women were divided into groups according to their use of intrauterine devices (IUDs), combination oral contraceptives (COC), condoms, and withdrawal methods.
Results: Based on information from 33 interviews with Turkish women, this qualitative research. Four different family planning strategies, the decision-making process, attitudes regarding the impact of family planning on sexual life, and four major themes were identified in the article. It has been observed that women are influenced by the environment and health personnel in family planning method choices and decision-making processes, they benefit from the internet, and their spouses are competent in the decision-making process.
Conclusion: In this study, it was found that gender norms gave men the authority to decide on reproduction; this means that their partner usually has the final say on the number of children a woman has or planning a pregnancy. The fact that women do not have their own preferences is beneficial in terms of documenting these preferences and concerns of health personnel, as well as integrating them into the design, implementation and evaluation of the intervention, taking into account their caution towards interventions.
Associations of Dietary Fructose and Sucrose Intake with HbA1c and Anthropometric Measurements in Patients with Type 2 Diabetes Mellitus
Authors: Kaner Gulsah , Ayer Cagla , Yalcin Tuba , Bakir Buse
Published: September 2023

Aim. This study aimed to evaluate the associations of daily dietary intake of fructose and sucrose with HbA1c levels and anthropometric measurements in patients with Type 2 diabetes mellitus. Methods. A total of 64 individuals were included in the study. Demographic characteristics, eating habits, frequency of fructose and sucrose source consumption, and dietary intakes were assessed through questioning. Anthropometric measurements, including body weight, height circumference (HtC), waist circumference (WC), hip circumference (HC), neck circumference (NC), wrist circumference (WrC), and mid-upper arm circumference (MUAC), were evaluated. The HbA1c level was categorized into two groups: good glycemic control (HbA1c≤ 7%) and poor (HbA1c> 7%) glycemic control. Results. The mean daily fructose and sucrose intakes were 10.57 ± 8.28 g (2.38 ± 1.96%), and 29.21 ± 24.78 g (6.29 ± 5.35%), respectively. All the anthropometric measurements assessed were lower in the group with good glycemic control; however, only in case of BMI, MUAC, NC, and WrC, these differences were significant. Patients with good glycemic control were found to consume more fruit. Anthropometric measurements were not related to daily fructose intake, but positively associated with sucrose intake and HbA1c levels. Specifically, HbA1c levels were negatively associated with fiber intake and positively associated with sucrose intake. Moreover, HbA1c levels were positively affected by NC and consumption of non-alcoholic carbonated drinks, and negatively affected by WC and consumption of sugar-containing instant coffee. Conclusions. The mean daily fructose intake among diabetics was found to be moderate and sucrose intake was consistent with the recommended range. The level of HbA1c was shown to be associated with all the anthropometric parameters assessed, and it was found that sugar-sweetened beverages could affect the level of HbA1c. However, further studies with larger sample sizes are needed to investigate these relationships more comprehensively.
Impact of Oral Habits and Buccal Frenulum on Gingival Microcirculation in Children: Findings and Clinical Significance
Authors: Makhlynets Nataliia , Antoniak Sofia , Pantus Andrii , Pavlyshyn Mariana , Ozhogan Zinovii
Published: September 2023

Background. Oral mucosal abnormalities such as abnormal lip frenulum, buccal frenulum, ankyloglossia are commonly observed in a routine dental practice. The close anatomical and functional relationship between the gingiva and the alveolar bone determines the significance of abnormal mucosal structures in the development of malocclusions and periodontal diseases. Oral habits are more prevalent in childhood; however, they can persist into adolescence and adulthood, potentially leading to dentofacial impairments and malocclusions. Therefore, there is a growing interest in understanding oral mucosal blood flow in the presence of oral habits and abnormal mucosal structures, as their combined effects may have a synergistic influence on the development of maxillomandibular anomalies.

Aim. This study was aimed to investigate age-depended parameters of gingival microcirculation in children with buccal frenulum, oral habits, and maxillomandibular anomalies.

Methods. This cross-sectional study involved 45 apparently healthy children and 180 children with oral habits, buccal frenulum, and maxillomandibular anomalies, divided into 3 age groups (ages 9 to 12, 12 to 15, and 15 to 17 years). Oral mucosal blood flow was assessed using a rheograph DX (Kharkiv, Ukraine) by measuring qualitative characteristics and quantitative parameters such as the vascular tone index (VTI), venous outflow index (VOI), peripheral resistance index (PRI), extensive blood flow index (EBFI), and rheographic index (RI). Statistical analysis included Spearman’s correlation, a Kruskal-Wallis H test, and a Dunn’s post-hoc test.

Results. The study revealed a significantly higher VTI in all patient groups, increasing with age and reaching +80.54% in the oldest age group compared to the respective control group. This elevation was accompanied by a moderate correlation enhancing the PRI (+4.61% in 9-12-year-old group to +33.42% in 15-17-year-old group). Furthermore, the VOI exhibited a noteworthy and age-dependent increase; however, there was a notable reduction in the RI (-41.10% to -59.70%) and EBFI values (-35.54% and -37.70% versus -23.97% in the youngest age group).

Conclusions. This study demonstrated a relationship between oral habits, buccal frenulum, and age-dependent disturbance of gingival microcirculation in children. The findings suggest that chronic traumatization due to oral habits and abnormal mucosal structures lead to increased vasoconstriction and impaired vessel elasticity. Early intervention and management of such category of patients are crucial for preserving optimal gingival microcirculation.
Verplaatsingspatronen voor, tijdens en na de covidcrisis: welke kansen zijn er (niet) gegrepen?
Authors: Van Eenoo Eva
Published: September 2023

Ondanks het initiële enthousiasme over de mogelijke kansen die de covidcrisis bracht, lijkt het nieuwe normaal verdacht veel op het oude normaal. In dit commentaar, met als geografische focus het Vlaams gewest, buig ik me over beleidsinterventies die verplaatsingspatronen trachtten te wijzigen tijdens en na de opeenvolgende lockdowns. Ik hou daarbij onder andere de rapporten van zowel het economisch als het maatschappelijk adviescomité tegen het licht, en sta ook stil bij sensibiliserende campagnes voor fietsgebruik. Ik betoog dat de business-as-usual het resultaat is van een op het individu gerichte kijk op gedragsverandering, het zogenaamde libertair paternalisme, waarin de Vlaamse regering de lockdown heeft geframed als marketingcampagne voor fietsen en thuiswerken. Tegelijkertijd ontwikkelde de regering een neoliberale kijk op het individu. Als alternatieve benadering schuif ik Social Practice Theory (SPT) naar voren die uitgaat van een wisselwerking tussen maatschappij en individu als verklaring voor gedrag. SPT is daarmee een interessant kader om naar de werkelijkheid te kijken, maatschappelijke verandering te analyseren en te gaan detecteren hoe transitieprocessen in gang kunnen worden gezet, en legt een breed veld aan beleidsinterventies open. SPT biedt daarom ook kansen om de klimaatcrisis te beheersen.
Stratagems of the Ukrainian and Russian troops in the battles for Kharkiv (February 24 - May 14, 2022)
Authors: Zadunaiskyi Vadym
Published: September 2023

Strategies, or military tricks, are a component of military art. They also play an important role in the modern Russian-Ukrainian war. Among the Ukrainian regions, one of the key ones is the Kharkiv region with a powerful administrative center – the city of Kharkiv. Therefore, in February-May 2022, heavy battles took place around Kharkiv. Then the Defense Forces of Ukraine successfully used 8 stratagems, which helped to defeat the Russian invaders and liberate a large area of the Kharkiv Region. Russian troops also tried to use 8 stratagems, but most of them were ineffective. The reason for this was the successful actions of the Ukrainian troops, including the ability to simultaneously use several stratagems, and the miscalculations of the Russian command. It overestimated the potential of Russian troops and underestimated the combat capability of the Defense Forces of Ukraine. During the the stratagems revealing, the author's approach to the definition and analysis of military tricks was used, which was tested in previous studies. The article states that the successful use of the stratagems by Ukrainian troops in 2022 may be a consequence of preserving the heritage of the Ukrainian Cossacks and their descendants. The ability of the Armed Forces of Ukraine to successfully use military tricks in the battles for Kharkiv confirmed the high level of their military art.