bluuebunny/crossref_metadata_2025 huggingface dataset:
Reabilitação bucal após exérese de carcinoma adenoide cístico
Authors: Leal Cristiane Maria Brasil , Nichthauser Brigitte , Braga Francisco Pantoja , Oliveira Lara Pepita de Souza , Freitas Guilherme Barbosa de , Silva Fernanda Cristina Cunha da , Aguiar Eduarda Cândida Gomes
Published: July 2022

Cirurgias oncológicas que envolvem a cavidade bucal podem provocar sequelas/mutilações como perdas estruturais do palato, língua, dentes e assoalho bucal, desencadeando problemas mastigatórios, fonéticos e estéticos, além de reclusão social. A reabilitação protética com próteses bucomaxilofaciais é uma indicação para reabilitação desses pacientes. Este trabalho visa relatar uma reabilitação com prótese total obturadora para reconstrução de palato resseccionado após maxilectomia parcial. Paciente do gênero feminino, 65 anos, diagnosticada com carcinoma adenoide cístico cribiforme foi submetida a maxilectomia parcial, que originou uma ampla comunicação bucosinusal, sendo posteriormente submetida a tratamento com radioterapia. Após anamnese e exames extra e intraorais, planejou-se a confecção de prótese total obturadora palatina. Os procedimentos clínicos consistiram na moldagem das arcadas superior e inferior, obtenção dos modelos, confecção e ajuste do plano de cera superior, obedecendo as características funcionais e estéticas da paciente, montagem dos modelos em articulador semiajustável, seleção e montagem dos dentes artificiais, prova estética e funcional dos dentes, moldagem de boca fechada e envio ao laboratório para acrilização. Com a prótese concluída, procedeu-se com a instalação, proservação e instruções à paciente, preconizando-se o uso de adesivo para potencializar a retenção e estabilidade da mesma. Os resultados clínicos demonstraram a eficácia da reabilitação e a paciente relatou melhora na deglutição, mastigação, fonética, estética e em seu convívio social. Nesse contexto, a prótese obturadora palatina mostra-se uma excelente opção de reabilitação para pacientes oncológicos mutilados por cirurgias ressectivas na região, permitindo o restabelecimento funcional e maior qualidade de vida.
Primary Health Care Approach to Achieving Universal Health Coverage in Nigeria: Are Extant Legal and Policy Regimes Adequate?
Authors: Nnamuchi Obiajulu , Ilodigwe Maria
Published: July 2022

The Declaration of Alma-Ata was quite categorical in projecting primary health care (PHC) as the key to attaining health for all or universal health coverage (UHC). PHC is not only the first level of interface between a patient and the health system, it is also the foundation of health systems and a crucial determinant of whether a health system is on a path to attaining UHC or otherwise. More recently, the World Health Assembly went a step further in not only affirming the link between PHC and UHC but also identifying a vital component of actualizing this goal, namely, social health insurance (SHI) system of health financing. In essence, to succeed in attaining UHC, countries must integrate PHC approach and SHI system into their national health architecture. This is critical given that for long, the capacity of PHC to deliver on its key mission, namely, improving efficiency in health care delivery, has been hampered by cost. Yet, cost challenges can be mitigated by adopting a SHI method of paying for health care. Nonetheless, whether extant legal and policy frameworks in Nigeria sufficiently address (if at all) this very crucial component of UHC is not at all clear – hence the significance of this paper.
Dysfunctional Nigerian Insurance Industry: Failure of Law or Regulation?
Authors: Okiche Ebelechukwu , Adibe Emeka , Obi-Ochiabutor Clara
Published: July 2022

This work interrogates the reason for the  poor performance of the Nigerian insurance industry. The reason for doing this is that there is a strong correlation between insurance and development. The illiterate villager in the remotest part of Nigeria understands the advantages of "pooling" in risk mitigation. A system of coming together to contribute resources into a pool in order to take a small percentage of same to compensate the few members of the group who suffer risks is very much part of the everyday life of the traditional Nigerian society. This is  what insurance is all about. Insurance, as we see it today, developed from this rudimentary aspect to the sophisticated business which it has become today. Being that our people are familiar with the tenets of insurance what then is the problem of Nigeria’s  modern insurance industry  that makes  it remain at the lowest ebb  in terms of performance in the financial services industry? Is the problem that of inadequacy in our law or ineffective regulation? Using the doctrinal method, the study examines both the legal  and the institutional framework for insurance business to ascertain what the problem is. Our finding is that notwithstanding some grey areas in the Insurance Act, 2003, the major problem of the industry is failure of regulation. We recommend that the regulator, the National Insurance Commission (NAICOM) be more proactive  to enable the industry take its pride of place in Nigeria as is the case all over the developed world.
PENGGUNAAN MEDIA PROYEKTOR DALAM MENINGKATKAN MOTIVASI BELAJAR SISWA PADA MATA PELAJARAN SEJARAH DI KELAS XI IPS 1 SMA NEGERI 9 PALU
Authors: Mutawakkil Mutawakkil , Puspita Putri Dewi
Published: July 2022

This study is a classroom action research conducted in 2 cycles consisting of four stages: planning, action implementation, observation and reflection. The result of analysis of affective assessment on pre action of student number 20 people expressed 4 and 4 unfinished students and the highest score was 79,5 and lowest score 32. The result of analysis obtained by students on activity of cycle I, there was an increase in affective appraisal and psychomotor using projector media. The result of affective appraisal showed 7 complete and unfinished students as many as 13 people with the highest score of 85.5 and the lowest score 58,8. While psychomotor assessment showed a complete student 4 and unfinished students 16 people with the highest score of 86.7 and the lowest score of 60.5. In cycle II there is a better improvement of affective and psychomotor assessment. The results of affective assessment showed a complete student as many as 19 people and students who do not complete as many as 1 person with a high score of 92.1 and a low score of 73.8. While the results of psychomotor assessment showed a complete student as many as 20 people with the highest score 92.1 and the lowest score 79.3. Performance of teachers also increased, in cycle I obtained a percentage of 78.33% and on the second cycle obtained percentage of 95%. Student activity in learning process also increase, in cycle I got percentage equal to 63,63% and in cycle II obtained percentage equal to 90,90%. These results can be concluded that the use of media projectors can improve student learning motivation in class XI IPS I SMA Negeri 9 Palu.
KEBIJAKAN PENDIDIKAN ISLAM PADA ERA GLOBALISASI, PASAR BEBAS DAN REVOLUSI INDUSTRI 4.0
Authors: Asmawi Muhammad Nur
Published: July 2022

This article examines Islamic education policies in the era of globalization, free markets and industrial revolution 4.0. A new era that emphasizes the pattern of digital economy, artificial intelligence, big data, robotic, and so on, or known as the disruptive innovation phenomenon. This paper seeks to reveal the shift in the function of contemporary education towards education as profit oriented. These social changes are addressed by the government with educational policies as public policies with their presence, among others: Kurikulum 2013, Kerangka Kualifikasi Nasional Indonesia (KKNI), e-learning, cyber University and so on to answer the challenges of the globalization era characterized by free markets and industrial revolutions 4.0.
THE APPLICATION OF CONTEXTUAL TEACHING AND LEARNING IN TEACHING ELLIPTICAL SENTENCES TO THE GRADE NINE STUDENTS OF SMP NEGERI 17 PALU
Authors: Ningtyas Putri
Published: July 2022

The Application of Contextual Teaching and Learning in Teaching Elliptical sentences to the Grade Nine Students of SMP Negeri 17 Palu. The objective of this research was to prove that the application of contextual teaching and leraning (CTL) can improve the ability of the grade nine students in constructing elliptical sentences. The sample of the research was taken by using cluster random sampling technique. Class IX B was the experimental class while IX C was the control class. The instruments used to collect the data were observation and tests. The results of observation were analyzed by using descriptive analysis. The results of tests were analyzed by applying statistic analysis. Applying 0.05 level of significance and 56 (29+29-2) degree of freedom (df), the writer found that t-test value (6.136) was greater than t-table value (2.007). It means that the application of contextual teaching and learning is effective to improve students’ ability in constructing elliptical sentences.
PENERAPAN STANDAR PROSES DALAM PEMBELAJARAN MATEMATIKA OLEH GURU YANG SUDAH DAN BELUM BERSERTIFIKAT PENDIDIK DI SMP KABUPATEN PINRANG
Authors: Mukaddas Iqbal
Published: July 2022

This study aims to describe the Application of Process Standards (planning, implementation, assessment) in mathematics learning by teachers who have been certified educators and who have not. The instruments used in this study are (1) learning planning (checklist and interview guide), (2) implementation process (observation sheet and interview guide), and (3) process assessment (checklist sheet and interview guide). The subject of this research is 6 mathematics subject teachers, which is divided into 3 teachers who have and 3 teachers who have not Certified Educator. The results of this research are (1) Application of process standard in mathematics learning by teachers who have already certified educator on (a) learning planning administration stated Good, (b) learning activity on application of professional competence by subject Teachers 1, Teacher 2 and Teacher 3 obtain category Fine, on the application of pedagogic competence by the subjects Teachers 1, Teachers 2 and Teachers 3 obtain the Very Good Rating category. (2) Application of process standard in mathematics learning by teachers who have not been certified educator on (a) learning planning administration stated Good, (b) learning activity on application of professional competence by subject of Teachers 5 and Teacher 6 obtained Good category and Teacher 4 obtained category Enough Good.
PENDIDIKAN PRANIKAH BERBASIS KELUARGA PADA REMAJA PUTRI DI KECAMATAN DAMPAL SELATAN
Authors: Rus'an Rus'an , Hamzah Hamzah
Published: July 2022

Masa remaja bagi anak perempuan berlangsung dalam usia 12-21 tahun. Masa ini dikenal sebagai masa yang penuhproblem, bukan saja bagi remaja putri itu sendiri, tetapi juga problem bagi orang tua, keluarga, dan lingkungannya.Bahkan lebih jauh lagi, ketidakharmonisan pascapernikahan dalam sebuah rumah tangga berdampak kompleks yangbermuara pada semakin melemahnya kualitas sumberdaya manusia secara makro. Dalam masa remaja peranan seorangibu sangat penting dan utama karena secara kodrati ia dikarunia oleh perasaan yang halus dan lembut, sehingga lebihtepat menjadi pembina bagi anak remajanya yang secara psikologis sedang bergolak.Secara metodologis, ada dua teknik pengumpulan data yang akan digunakan dalam penelitian ini yaitu angket danwawancara mendalam. Pengisian angket akan didampingi oleh peneliti. Dengan demikian tingkat kesalahan penelitiandapat ditekan sekecil mungkin dan persentase pengembalian jawaban lebih tinggi. Wawancara dilakukan secarainformal. Dengan cara ini informasi yang diperoleh diharapkan akan semakin banyak, mendalam, dan lebihmenggambarkan keadaan yang sesungguhnya. Selanjutnya data penelitian akan dianalisis secara kuantitatif dankualitatif. Analisis kuantitatif yang digunakan adalah analisis deskriptif seperti persentase, rerata, dan mode. Sedanganalisis kualitatif yang diterapkan adalah analisis domain dan analisis taksonomis.Hasil penelitian menunjukkan bahwa pada umumnya taraf pengetahuan ibu-ibu rumah tangga tentang pendidikanpranikah bagi remaja putri mereka, berada pada taraf sedang 57.3% dan rendah 23.3%. sedangkan pada umunyapengetahuan remaja putri tentang pendidikan pranikah berada pada taraf sedang 56.0% dan rendah 28.7%.Presepsi/sikap ibu-ibu rumah tangga terhadap pranikah bagi remaja putrinya sebanyak 50.0% adalah rendah dan 32.7 %adalah sedang. Presepsi/sikap anak remaja putri tentang pendidikan pranikah juga pada umumnya rendah yakni 52.2%dan sedang 36.7%. Kemudian, peranan lembaga keluarga pada umumnya bertaraf sedang yakni sebanyak 68.0%sedangkan yang sudah tergolong tinggi sebanyak 24.7%.
PEMBAHARUAN PENDIDIKAN ISLAM HARUN NASUTION (Kajian Filsafat Pendidikan)
Authors: Kasmiati Kasmiati
Published: July 2022

his article shows the renewal of Islamic education by Harun Nasution in terms of educational philosophy. Aaronstrongly believed that the superiority of human reason. Harun then asserted that reason can understand the purpose ofrevelation, so that reason and revelation can be in line and in line in creating civilization. According to Harun that alQur'an and hadith both give a high position to reason and seek knowledge. According to him that this high appreciationof reason gives rise to a liberal theological style in Islam, in addition to the revelations coming down to help the humanmind in knowing things that lie beyond the reach of human reason. This has earned ijtihad according to him is the thirdsource in Islam, in addition to al-Qur'an and hadith. Ijtihad in various fields has given birth to the face of Islam in manyaspects, such as: theology, worship, morals, mysticism, philosophy, history and culture. Knowledge that is only one ortwo aspects or one aspect will only lead to incomplete understanding, misunderstanding, narrow and rigid.
PENGEMBANGAN ASESMEN BERBASIS KURIKULUM 2013 UNTUK MENGUKUR KEMAMPUAN BERFIKIR KRITIS GURU IPA SMP NEGERI KABUPATEN DONGGALA
Authors: Istadewi Ika
Published: July 2022

Tujuan penelitian ini untuk mengembangkan asesmen tes berbasis kurikulum 2013 untuk mengukur kemampuanberfikir kritis guru IPA SMP Negeri Kabupaten Donggala. Jenis penelitian yang digunakan adalah penelitian denganmenggunakan metode Research and Development (R & D) yang mengacu pada model pengembangan Plomp yangterdiri dari beberapa fase yaitu: (1) Fase Investigasi awal, (2) Fase desain, (3) Realisasi, (4) Fase tes, evaluasi dan revisi.Sebagai sampel dalam penelitian adalah guru mata pelajaran IPA SMP Negeri Kabupaten Donggala berjumlah 30orang. Metode pengumpulan data dalam penelitian dan pengembangan meliputi: (1) Studi pendahuluan, (2) Pembuatantes asesmen berbasis kurikulum 2013 dan (3) Pengujian dan perbaikan tes asesmen. Tes yang digunakan adalah tesuraian untuk mengukur kemampuan guru IPA dalam mengembangan kemampuan berfikir kritis melalui tes asesmenberbasis kurikulum 2013. Teknik analisis data yang digunakan adalah tehnik deskriptif kualitatif dengan uji validitas,realibilitas, tingkat kesukaran dan daya pembeda.Hasil penelitian dapat disimpulkan bahwa pengembangan tes asesmen berbasis kurikulum 2013 dapat mengukurkemampuan berfikir kritis guru IPA SMP Negeri Kabupaten Donggala. Hal ini ditunjukkan dari hasil evaluasiinstrumen tes oleh ahli materi, desain dan praktisi menunjukkan kategori sangat baik dengan rata-rata persentasepenilaian antara 85,47% sampai dengan 90,71%. Hasil uji validitas tes berpikir kritis dari sepuluh indikator yangdijadikan butir soal dalam penelitian sudah Valid dengan menggunakan taraf signifikan 5%, hasil uji reabilitasdiperoleh nilai rata-rata sebesar 0,95 yang lebih besar dari rata-rata rtabelnya sehingga tingkat reabilitasnya SangatTinggi, untuk tingkat kesukaran soal Tergolong kategori Sedang dan kategori Sukar dan uji daya pembeda soalberdasarkan analisis tes tergolong Sangat Baik, Baik dan Cukup.
PENGEMBANGAN SIKAP SPIRITUAL PESERTA DIDIK PADA PEMBELAJARAN PENDIDIKAN AGAMA ISLAM (PAI) DI SDN 12 PALU
Authors: Alhabsyi Firdiansyah , Hasanah Faridahtul
Published: July 2022

Tulisan ini berkaitan dengan pengembangan sikap spiritual peserta didik pada pembelajaran Pendidikan Agama Islam (PAI) di SDN 12 Palu sangat mengutamakan pembentukan karakter Islami peserta didik, mengingat banyaknya pengaruh budaya asing yang dapat merusak moral anak bangsa, maka dari itu penanaman sikap spiritual ini sangatlah penting bagi peserta didik. Kemudian efektivitas pembelajaran Pendidikan Agama Islam (PAI) sebagai bentuk upaya pengembangan sikap spiritual di SDN 12Palu, sangat signifikan dalam merubah dan membentuk kepribadian peserta didik, agar dapat merubah sikap dan perilaku belajar peserta didik.
“Methy Imbiß” by M.E.S.H.: Concealed Politics
Authors: Liechti Hannes
Published: July 2022

A detailed analysis of the sampling strategy behind the track “Methy Imbiß” by M.E.S.H. M.E.S.H. is the artist James Whipple (*1985), who was born, grew up, and was educated in various places in the U.S. before moving to Berlin in 2009. Whipple published his first album "Piteous Gate" in 2015 and his second album "Hesaitix" in 2017. The track “Methy Imbiß” (PAN Records 2015) forms part of his first fulllength album and contains a hidden sample of war sounds from the military conflict in Eastern Ukraine in 2014.
“STABILIZED, YES!” by COOL FOR YOU: a Political Message
Authors: Liechti Hannes
Published: July 2022

A detailed analysis of the sampling strategy behind the track "STABILIZED, YES!" by COOL FOR YOU. The brain behind the project COOL FOR YOU is German interdisciplinary artist Vika Kirchenbauer (*1983), based in Berlin. On all her releases Kirchenbauer exclusively processes material from the Northern American Sacred Harp tradition, a religious choral tradition stemming from a colonial context.
Terminology and Methods
Authors: Liechti Hannes
Published: July 2022

In Chapter 2 I will introduce and clarify the terms and concepts most important to this study. Starting with an extensive definition of “sampling” from three angles (field-based, literature-oriented, and personal), I will continue by discussing “the political” and the two cultural concepts of “meaning” and “material.” Another concern of this chapter will be the description and characterization of the field of research, experimental electronica, and a short definition of my understanding of “popular music.” The second part of this chapter is dedicated to a discussion of my methodological approach, including a suggestion for a new field of study, trackology, focusing on the analysis of tracks.
A Strategic Assessment of Needs and Opportunities for the Wider Adoption of Electric Vehicles in Indiana
Authors: Konstantinou Theodora , Chen Donghui , Flaris Konstantinos , Kang Kyubyung , Koo Dan Daehyun , Sinton Jonathon , Gkritza Konstantina , Labi Samuel
Published: July 2022

The primary objective of this study was to assess the challenges and opportunities associated with the provision of appropriate infrastructure to support electric vehicle (EV) operations and electrification across Indiana. A secondary objective of this study was to develop a strategic plan for INDOT that outlines new business opportunities for developing EV charging stations. To achieve these objectives, the project team assessed current and emerging trends in EV operations, particularly EV charging infrastructure and EV demand forecasting. They also examined opportunities for the strategic deployment of EV charging stations by identifying EV infrastructure deficit areas; investigated the impact of EV adoption on highway revenue and the feasibility of new revenue structures; and evaluated strategic partnerships and business models. The agent-based simulation model developed for future long distance EV trip scenarios enables INDOT to identify EV energy deficient areas for current and future energy charging demand scenarios, and it can support Indiana’s strategic plans for EV charging infrastructure development. The results of the revenue impact analysis can inform INDOT’s revenue model. The estimations of the recovery EV fee, the VMT fee, and pay-as-you-charge fee that break-even the fuel tax revenue loss can be used by INDOT in pilot programs to capture users’ perspectives and estimate appropriate fee rates and structures. The insights obtained from the stakeholder interviews can be used to enhance preparedness for increasing EV adoption rates across vehicle classes and to strengthen the engagement of different entities in the provision of charging infrastructure.
Der pädagogische Fachwortschatz des Deutschen in Zeiten der COVID-19-Pandemie: Eine onomasiologische Analyse
Authors: Palytsya Halyna , Storonska Oksana
Published: July 2022

Der vorliegende Beitrag stellt die Forschung von Auswirkungen der COVID-19-Pandemie auf die Entwicklung des pädagogischen Wortschatzes der deutschen Sprache vor. Sein Ziel besteht in der onomasiologischen Analyse der pädagogischen Fachlexik der Corona-Zeit sowie ihrer qualitativen und quantitativen Charakterisierung. Das Material der Forschung stellt das dem Neologismenwörterbuch. Neuer Wortschatz rund um die Coronapandemie des Leibniz-Institutes für deutsche Sprache (NWB) entnommene Korpus zum pädagogischen Corona-Vokabular mit der Gesamtzahl von 79 lexikalischen Einheiten dar. Alle extrahierten Wörter und Wortverbindungen wurden aufgrund der Gemeinsamkeit der von ihnen bezeichneten Aspekte der Bildungswirklichkeit in der Pandemie-Zeit in fünf thematische Gruppen eingeordnet, und zwar (1) Bildungsansätze, (2) Unterrichtsgestaltung, (3) Leistungskontrolle, (4) Bildungssubjekte, (5) Didaktische Versorgung. Jede dieser Gruppen ist durch die Bedeutungsnuancen ihrer Elemente charakterisiert. Infolge eingehender Betrachtung wurden innerhalb der thematischen Gruppen einzelne Untergruppen zur Bezeichnung verschiedener Aspekte der jeweiligen Bildungserscheinungen festgestellt. ImRahmen der thematischen Gruppen und Untergruppen wurde auch eine quantitative Bewertung vorgenommen, derzufoge die Gruppe Unterrichtsgestaltung mit 44,3 % die größte Menge bildet, während die Gruppen Bildungssubjekte und Didaktische Versorgung mit 6,3 % die gerings
Functional Transposition of ‘ON’ from a Diachronic Perspective
Authors: Kovbasko Yurii
Published: July 2022

The paper represents a distinctive attempt to trace the development of the preposition and the adverb ‘on’ as the initial and transposed categories. The study focuses on their evolution throughout 16 historical time spans – since 850 and up to the present time. The research is based on 7 954 Old English, 2 368 Middle English, 4 251 Early Modern English examples, which have been obtained from the Helsinki Corpus of English Texts and analyzed without applying any corpus software; 174 581 examples of Late Modern English from the Corpus of Late Modern English Texts, which have been processed by means of the Lancsbox software tool; and the statistical data on 7 118 454 examples of Present-Day English retrieved from the Corpus of Historical American English and the British National Corpus. The paper attests that ‘on’ is formed at the first stage (before 850) of the Old English period as the preposition and at the next stage (850–950) is transposed into the category of the adverb, which is characterized by a further slight increase in the statistics and stabilization of its correlation with the preposition ‘on’. Correlation between the categories had remained stable up to the Early Modern English period, when the category of the adverb has started its sustainable growth, which is currently being observed in the English language. The paper proves that in Early Modern English the process of functional transposition is superseded by an utterly new stage of lexicalization which leads to formation of phrasal verbs.
Hypo- and Hyperphosphatemia at Admission as Independent Factors of Mortality of COVID-19 Patients: Findings from a Retrospective Cohort Study
Authors: Hadavi Marzieh , Taghinezhad Fakhredin , Shafiei Elham , Babakr Sharif Hama , Bastaminejad Saiyad , Kaffashian Mohammadreza , Ahmadi Iraj , Mozafari Aliashraf
Published: July 2022

Background: Electrolyte imbalances are common in COVID-19 infection and are associated with poor outcomes in hospitalized patients. Objectives: This study examined whether serum phosphate imbalances at admission are associated with mortality in hospitalized COVID-19 patients. Methods: In this registry-based single-center retrospective cohort study, 1349 inpatients with COVID-19 were included from March 2020 to March 2021 in an academic hospital in Ilam (southwest Iran). The Cox proportional hazard (PH) regression model was applied to the data set of COVID-19. Results: The in-hospital median survival time for patients with low, normal, and high serum phosphate levels was 14, 25, and 8 days, respectively. In a multivariate model, adjusted for the other variables, patients with hypophosphatemia (adjusted hazard ratio [HR], 2.53; 95% CI, 1.15 - 5.58; P = 0.02) and hyperphosphatemia (adjusted HR, 1.77; 95% CI, 1.00 - 3.14; P = 0.05) had an increased mortality hazard compared with those who had normal levels of serum phosphate. Conclusions: Our results demonstrate associations of hypophosphatemia and hyperphosphatemia with increased in-hospital mortality in COVID-19 patients. Intensive medical care and more attention must be paid to COVID-19 patients with serum phosphate imbalances at admission.
The Effectiveness of Acceptance and Commitment Therapy, Transcranial Direct Current Stimulation, and Pharmacotherapy on The Sleep Quality of Women with Chronic Pain: A Randomized Clinical Trial
Authors: Lotfi Jabali Atefeh , Mojtabaei Mina , Mirhashemi Malek
Published: July 2022

Background: Sleep quality is a major factor affecting physical and mental health. Poor sleep quality is a common complaint in many psychiatric disorders. Objectives: The present study aimed to investigate the effectiveness of acceptance and commitment therapy (ACT), transcranial direct current stimulation (tDCS), and pharmacotherapy on the sleep quality of women with chronic pain in Tehran, Iran. Methods: This randomized clinical trial with a pre-test, post-test, and follow-up design and a control group was performed on the statistical population of all women with chronic pain visiting Pardis Pain Clinic, Tehran, Iran, in 2020. The sample consisted of 60 women with chronic pain. We randomly divided the participants into four groups ACT, pharmacotherapy, tDCS, and control (N = 15 per group). The research instrument was the Pittsburgh sleep quality index (PSQI). The data were analyzed using repeated measures analysis of variance by the SPSS software. Results: The participants aged 46.67 ± 8.39, 48.24 ± 7.54, 47.67 ± 7.42, and 47.39 ± 6.85 years in the ACT, pharmacotherapy, tDCS, and control groups, respectively. ACT (F = 7.76, P < 0.001), pharmacotherapy (F = 17.97, P < 0.001), and tDCS (F = 9.37, P < 0.001) significantly improved the sleep quality of patients with chronic pain compared to the control group. The effects of ACT, pharmacotherapy, and tDCS on the sleep quality of women with chronic pain did not significantly differ (P > 0.05). Conclusions: ACT and tDCS intervention programs effectively improved the sleep quality of patients with chronic pain. Therefore, ACT and tDCS are recommended to enhance sleep quality in chronic pain patients.
Survey Method of Vascular Surgery on the Onset of Ischemic Steal Syndrome Following Vascular Access in Dialysis Patients
Authors: Mousavi Seyed Masood , Nazari Iraj , Chanany Rahim
Published: July 2022

Background: Access to arteries is one of the most appropriate approaches for helping chronic kidney diseases. Objectives: The aim of the present study was to evaluate the survey method of vascular surgery on the onset of ischemic limb syndrome following vascular access in dialysis patients. Methods: In this cross-sectional study, the population study was patients with end-stage renal disease (ESRD) referring to Ahvaz Golestan Hospital in 2018. Control of limbs temperature and comparison with the other side, before and after surgery, feeling cold by the patient, control of organs pulse and comparison with the other side, pain of organs comparing to the other side, pain during the dialysis, paresthesia, and movement failure and during dialysis, and organs atrophy-ulcer were measured. Results: In the present study, 294 patients, including 139 women (46.94%) and 156 men (53.06%), were studied. Ischemic steal syndrome (ISS) was observed in 20 patients, that 13 cases of them had benefited from fistula approach and 7 patients used graft approach. The most common observed ISS was related to brachiocephalic fistula approach (AVF-Brachiocephalic) and then graft in arm. In non-steal syndrome group, brachiocephalic fistula (AVF-Brachiocephalic) had the most common application. In the present study, there was no significant correlation between access method and underlying diseases of high blood pressure, diabetes, and cardiac ischemic diseases. Conclusions: One of the most important results of the present study was the highest existence of steal syndrome in brachiocephalic approach, which is confirmed by other studies.
Investigating Buffer Effects on Lysozyme Adsorption to Borosilicate Glass
Authors: Downey John Donal , Crean Abina , Ryan Katie B
Published: July 2022

Proteinadsorption refers to the accumulation and adherence of a protein to the surfaceof a solid, but without surface penetration occurring. Proteins can adsorb to avariety of interfaces that are used in the manufacture, formulation, and storageof protein medicines. This can have unintended consequences such as a loss ofexpensive protein product and aggregate formation. This study investigates the role ofbuffer composition, pH, and protein concentration on the adsorption of lysozymeto borosilicate glass. Using reverse-phase HPLC and differential scanning fluorimetry, wequantified the mass of adsorbed lysozyme and assessed the stability of lysozymein each buffer system. The highest amount of adsorbed lysozyme occurredin the sodium phosphate and histidine-HCl buffers at pH 7.4 and stabilityanalysis showed that lysozyme had the lowest melt temperature in these buffers. 
Characterizing RAPIDTM platelet and leukocyte-rich plasma gels – an autologous, point-of-care medicine for diabetic foot ulcer treatment.
Authors: Olszewska Aleksandra , Pitchford Simon , Rickard James , Forbes Ben
Published: July 2022

In 2017/18 wound healing cost the NHS 8.3 billion pounds. There is an urgent need for more effective, accessible, and safe treatments. Platelet-rich plasma (PRP) therapies have been emerging since the early 2000s, currently they are used across various medical fields treating conditions from cosmetic procedures through burn treatments to wound healing. RAPIDTM gel is a product for the treatment of diabetic foot ulcers that is currently in stage 2b of clinical trials. This project aims to better understand the properties of the gel and how these are affected by the manufacturing process. The PRP gels were characterized physiochemically by exploring the gel time, exudate release and growth factor content. These data provide a baseline for future studies exploring how variations in manufacturing conditions affect the gel properties.
Learning analytics: Prospects and challenges
Authors: Šereš Laslo , Pavlićević Veselin , Petrović Goran , Horvat Danijel , Ivanišević Rajko
Published: July 2022

Owing to its high promises for improving learning support, teaching, and learning outcomes in higher education, learning analytics has captured much interest from both academics and practitioners over the last several years. Considering that it is rooted in several disciplines, researchers and practitioners have approached learning analytics from a range of perspectives. Although many studies concerning learning analytics have highlighted its great potential for improving learning practice, there is little evidence of successful transfer of the suggested potential into the practice of higher education happening. This clearly indicates a need for rethinking many aspects of learning analytics usage: first, the goals that can be achieved, but also the actions necessary to attain these goals. The aim of the descriptive research presented in this paper is to provide an updated and realistic view of the state of the art in learning analytics, its potential benefits, and tangible challenges that need to be overcome for a successful application of learning analytics as educational technology.
Partisan discrimination without explicit partisan cues
Authors: Lyons Jeffrey , Utych Stephen M.
Published: July 2022

Much research has demonstrated that Democrats and Republicans use information about party affiliation to discriminate against one another. However, we know little about how people gain the necessary information about other people’s partisanship to engage in discriminatory behavior. We explore whether people perceive partisanship when shown only images of faces, and whether they then use these perceptions to engage in partisan discrimination. We find that they do. Using two studies we show that the partisan perceptions people derive from seeing images of faces influence discrimination of job applicants, and propensities to engage is a wide range of social interactions. People appear to be making judgements about partisanship using only facial appearance, and are willing act on that perception. The implication of this finding is that partisan discrimination is likely widespread, and does not require the explicit communication of partisan affiliations.
Neoadjuvant Radiotherapy After (m)FOLFIRINOX for Borderline Resectable Pancreatic Adenocarcinoma: A TAPS Consortium Study
Authors: Janssen Quisette P. , van Dam Jacob L. , Prakash Laura R. , Doppenberg Deesje , Crane Christopher H. , van Eijck Casper H.J. , Ellsworth Susannah G. , Jarnagin William R. , O’Reilly Eileen M. , Paniccia Alessandro , Reyngold Marsha , Besselink Marc G. , Katz Matthew H.G. , Tzeng Ching-Wei D. , Zureikat Amer H. , Groot Koerkamp Bas , Wei Alice C. , _ _
Published: July 2022

Background: The value of neoadjuvant radiotherapy (RT) after 5-fluorouracil with leucovorin, oxaliplatin, and irinotecan, with or without dose modifications [(m)FOLFIRINOX], for patients with borderline resectable (BR) pancreatic ductal adenocarcinoma (PDAC) is uncertain. Methods: We conducted an international retrospective cohort study including consecutive patients with BR PDAC who received (m)FOLFIRINOX as initial treatment (2012–2019) from the Trans-Atlantic Pancreatic Surgery Consortium. Because the decision to administer RT is made after chemotherapy, patients with metastases or deterioration after (m)FOLFIRINOX or a performance score ≥2 were excluded. Patients who received RT after (m)FOLFIRINOX were matched 1:1 by nearest neighbor propensity scores with patients who did not receive RT. Propensity scores were calculated using sex, age (≤70 vs >70 years), WHO performance score (0 vs 1), tumor size (0–20 vs 21–40 vs >40 mm), tumor location (head/uncinate vs body/tail), number of cycles (1–4 vs 5–8 vs >8), and baseline CA 19-9 level (≤500 vs >500 U/mL). Primary outcome was overall survival (OS) from diagnosis. Results: Of 531 patients who received neoadjuvant (m)FOLFIRINOX for BR PDAC, 424 met inclusion criteria and 300 (70.8%) were propensity score–matched. After matching, median OS was 26.2 months (95% CI, 24.0–38.4) with RT versus 32.8 months (95% CI, 25.3–42.0) without RT (P=.71). RT was associated with a lower resection rate (55.3% vs 72.7%; P=.002). In patients who underwent a resection, RT was associated with a comparable margin-negative resection rate (>1 mm) (70.6% vs 64.8%; P=.51), more node-negative disease (57.3% vs 37.6%; P=.01), and more major pathologic response with <5% tumor viability (24.7% vs 8.3%; P=.006). The OS associated with conventional and stereotactic body RT approaches was similar (median OS, 25.7 vs 26.0 months; P=.92). Conclusions: In patients with BR PDAC, neoadjuvant RT following (m)FOLFIRINOX was associated with more node-negative disease and better pathologic response in patients who underwent resection, yet no difference in OS was found. Routine use of RT cannot be recommended based on these data.
The Role of Immunotherapy in the Management of Soft Tissue Sarcomas: Current Landscape and Future Outlook
Authors: Banks Lauren B. , D’Angelo Sandra P.
Published: July 2022

Soft tissue sarcomas (STS) are a subset of sarcoma, a rare group of heterogeneous malignancies of mesenchymal origin. Current standard of care involves surgical resection with systemic chemotherapy used to treat high-risk localized and metastatic disease. Though classically thought to be immunologically quiet tumors, STS interact with the immune system, undergoing immunoediting that alters tumor immunogenicity and the tumor microenvironment. Recent advances with immune checkpoint inhibition have led to clinical trials exploring the efficacy of immunotherapy in treating STS. Results from these trials point to histologic subtype–specific clinical activity of immune checkpoint blockade. In addition, combinatorial strategies adding immune checkpoint inhibition to local or systemic therapies for STS have further increased their efficacy. Targeted immunotherapies using engineered T-cell receptor–based approaches also show increasing promise as treatment options for some patients with STS. Adoptive transfer of autologous T cells targeting NY-ESO-1 and MAGE-A4 have high response rates in sarcomas expressing these antigens, although recurrence is often seen in responding patients. Future work must focus on identifying primary and acquired mechanisms of resistance to these therapies, and extend T-cell receptor discovery to other tumor-associated antigens.
Asiatisk resignation
Authors: Ehlers Dam Anders
Published: July 2022

This article offers a reading of Herman Bang’s Novel De uden Fædreland – (Those Without a Nation–) under the perspective of the so-called “Yellow Peril”, a wide- spread theory at the beginning of the 20th century, which believed that Europe was threatened by a pan-Asian movement. The article claims that Bang’s fear of Asia and of European decline is mixed with a certain sympathy for Buddhism and the idea of resignation.
Game frames y populismo en las elecciones al Parlament de Catalunya de 2021. Actividad, temas y discursos de los candidatos en Twitter.
Authors: Ibáñez-Cuquerella Miguel
Published: July 2022

Este trabajo analiza la actividad en Twitter de los candidatos a la presidencia de la Generalitat en las elecciones al Parlament de Catalunya del 14 de febrero de 2021. El objetivo de la investigación es conocer qué uso han dado los candidatos a sus perfiles en Twitter, de qué temas han hablado y qué estrategias discursivas populistas han empleado. A través de una triangulación metodológica, el estudio aplica un análisis cuantitativo de la actividad en Twitter, un análisis temático de contenido y un análisis del discurso. Los resultados obtenidos muestran que los candidatos utilizaron Twitter de una forma unidireccional y que solo interactuaron con sus esferas partidistas, que usaron más los game frames –enmarcados para obtener votos– que los issue frames –propuestas sectoriales concretas– y que mostraron diversos rasgos de comunicación populista en sus discursos.
Exploring User Engagement with Portuguese Political Party Pages on Facebook: Data Sprint as Workflow
Authors: Martins Rosa Jorge , Bacaksızlar Turbic N. Gizem , Magalhães Telles Alda , González Tosat Clara , Jiménez Ruiz Cristian , Moraiti Kalliopi , Özgür Karadeniz Oğuz , Pallacci Valentina
Published: July 2022

In the broader context of a research project about political participation on Facebook during the Portuguese electoral year of 2019 - for the European Parliament in May, and for the National Parliament in October -, a dataset of more than 9,000 posts and corresponding reactions and comments had been previously retrieved using Facepager. Participating in a data sprint came up as an opportunity to explore some specific questions in an intensive and time-bound context, using a subset of the data tailored to the purpose of discovering: 1) how differently official parties tried to engage with Facebook users before, during, and after the campaigns for the major elections periods (“supply side”), and 2) what type of content received the most attention and engagement (“demand side”). Our results show that regardless of the party’s age and position in the political spectrum, the persistent main categories are “National Politics”, “Fundamental Rights”, and “Self-Promotion” for both elections. Also, we found that posts with images attract more attention, and apparently this may be leveraged if the textual content of the post is in topics of “National Politics”. However, this finding requires further investigation. Along with details about the research during the data sprint and the main findings, this paper is also a testimony about the singularities and learnings of a process built upon the constraints of taking data sprints situation as a workflow.
Staging and storing data sprint-based research results: a communication design approach
Authors: Gobbo Beatrice , Briones Rojas María de los Ángeles , Aversa Elena , Elli Tommaso , Benedetti Andrea , Mauri Michele , Colombo Gabriele
Published: July 2022

Data sprints are multidisciplinary, time-limited, practice-oriented, and group activities that explore complex issues through data gathering, visualization, and analysis. Data sprints usually conclude with final presentations where participants showcase the research process they followed and the achieved results. Although this activity is now widespread in some research centers, there does not appear to be a data-sprint tailored dissemination format that can support the organization, archive, and online diffusion of results. Starting from the experience of a data sprint on Digital Methods, the paper describes the design process of a digital format which condenses and reinterprets good practices already in use in current supports for disseminating data sprints results. The design process of the format is structured in two steps: (i) designing and (ii) staging the format. The former aims to dissect and recompose data sprint results in hierarchical block structures filled with variable contents; the latter describes outcomes that emerged during a preliminary evaluation phase with experts and a stress-test activity. The format is a container that participants can fill at the end of a data sprint to organize, archive, and present research results. Evaluation activities confirmed the efficiency of the format, which is distinguished by its nested structure and flexibility with different content. Future research opportunities concern the ultimate implementation of the format as a public Content Management System to be used even outside data sprint contexts, such as disseminating more thorough research and teaching students how to structure Digital Methods research.
Research and Development of the Synchronous Reluctance Motor Traction Drive
Authors: Zarembo Jaroslavs
Published: July 2022

The aim of the Doctoral Thesis is the design, development and testing of an electric drive based on SynRM and a two-level frequency inverter for traction application. Within the research an electric motor in the overall dimensions of an existing serial induction motor for the trolleybus was developed, manufactured, and investigated. The result of the work was the development and testing of a new model of traction SynRM with control system for trolleybus drive. The Doctoral Thesis has been written in English. It consists of an Introduction, 5 chapters, Conclusions, 58 figures, 12 tables, and 2 appendices; the total number of pages is 80, including appendices. The Bibliography contains 40 titles.
Cryo-EM structures reveal that RFC recognizes both the 3′- and 5′-DNA ends to load PCNA onto gaps for DNA repair
Authors: Zheng Fengwei , Georgescu Roxana , Yao Nina Y , Li Huilin , O'Donnell Michael E
Published: July 2022

RFC uses ATP to assemble PCNA onto primed sites for replicative DNA polymerases δ and ε. The RFC pentamer forms a central chamber that binds 3′ ss/ds DNA junctions to load PCNA onto DNA during replication. We show here five structures that identify a second DNA binding site in RFC that binds a 5′ duplex. This 5′ DNA site is located between the N-terminal BRCT domain and AAA+ module of the large Rfc1 subunit. Our structures reveal ideal binding to a 7-nt gap, which includes 2 bp unwound by the clamp loader. Biochemical studies show enhanced binding to 5 and 10 nt gaps, consistent with the structural results. Because both 3′ and 5′ ends are present at a ssDNA gap, we propose that the 5′ site facilitates RFC’s PCNA loading activity at a DNA damage-induced gap to recruit gap-filling polymerases. These findings are consistent with genetic studies showing that base excision repair of gaps greater than 1 base requires PCNA and involves the 5′ DNA binding domain of Rfc1. We further observe that a 5′ end facilitates PCNA loading at an RPA coated 30-nt gap, suggesting a potential role of the RFC 5′-DNA site in lagging strand DNA synthesis.
Polimorfismos del gen de la apolipoproteína E en adultos mayores de 60 años con disminución de la memoria cognitiva y enfermedad de Alzheimer en diferentes poblaciones venezolanas
Authors: Martínez Silvia , Ochoa Bárbara , Pérez María Rafaela , Torrico Fátima , García Ildemaro , Garcia Carmen Cristina
Published: July 2022

Introducción. La enfermedad de Alzheimer constituye un problema de salud pública que tiende a agravarse en el tiempo. Entre los factores genéticos de predisposición más importantes, se encuentra la presencia del alelo ε4 del gen APOE que codifica para la apoproteína E.Objetivo. Determinar las frecuencias alélicas y genotípicas de las isoformas de APOE en adultos mayores de 60 años con memoria cognitiva disminuida y Alzheimer, en la gran Caracas y en la comunidad indígena pemón de la zona Kamarata-Kanaimö, Estado Bolívar. Materiales y métodos. Se estudiaron 267 pacientes: 96 controles, 40 con memoria cognitiva disminuida y 108 con Alzheimer procedentes de Caracas, y 23 individuos deKamarata-Kanaimö. Las isoformas de APOE se determinaron con el estuche AP1210Z: Seeplex ApoE genotyping™.Resultados. El alelo ε4 mostró asociación significativa con la memoria cognitiva disminuida (OR=5,03; IC95% 0,98-25,70) y la enfermedad de Alzheimer (OR=5,78; IC95% 1,24-26,85). Las frecuencias genotípicas de los grupos de control y con memoria cognitiva disminuida, fueron: ε3/ε3> ε3/ε4> ε2/ε4> ε3/ε2> ε4/ε4, y las del grupo con Alzheimer: ε3/ε3> ε3/ε4> ε4/ε4> ε2/ε4> ε3/ε2. En Kamarata-Kanaimö, el orden fue ε3/ε3> ε3/ε4> ε4/ε4 y no se encontró el alelo ε2. Conclusiones. Las frecuencias alélicas y genotípicas de APOE en la muestra tuvieron una distribución similar a la de otros estudios en Venezuela y las Américas. La ausencia del alelo ε2 en la comunidad indígena de Kamarata-Kanaimö amerita mayor investigación. Se constató la asociación positiva del alelo ε4 en personas con la enfermedad de Alzheimer y con memoria cognitiva disminuida. Conocer precozmente los pacientes portadores de este alelo puede ayudar a establecer medidas preventivas en nuestra población.