bluuebunny/crossref_metadata_2025 huggingface dataset:
Epigenetic graphitization in the basement of the Siberian craton - evidence of the migration of hydrocarbon-enriched fluids in the paleoproterozoic
Authors: Savelyeva V. B. , Danilova Yu. V. , Shumilova T. G. , Ivanov A. V. , Danilov B. S. , Bazarova E. P.
Published: June 2019

For the first time, diagnostics and structural studies of the сarbonaceous material (СM) of quartz-muscovite dinamoschists from schistase zones in biotite migmatites, pegmatites and diabases of the southern part of the Baikal ledge of the Siberian craton were performed. The сarbonaceous material is represented by clearly and microcrystalline graphite with residual hydrocarbon radicals. Native Ni, Sn, zincous Cu, intermetallic compounds of Fe-Ni composition, copper sulfides, rutile, monazite, and zircon were found in intergrowths with СM. The carbon isotopic composition is from -29.19 to -31.58‰, with the exception of CM from schistated diabase with δ13C = -24.93 ‰. The 40Ar/39Ar-dating of muscovite gave an age of 1947 ± 7.8 Ma, indicating a relationship between dynamometamorphism and the accretion of the Akitkan folded system with ancient craton complexes. It is concluded that the deposition of native carbon and metals is caused by the migration of essentially hydrocarbon fluid in the upper crustal formations.
The nature of philogopite-ilmenite and ilmenite paragenesises in deep-seated xenoliths from Udachnaya kimberlite pipe
Authors: Solov’eva L. V. , Kostrovitsky S. I. , Kalashnikova T. V. , Ivanov A. V.
Published: June 2019

The article describes the petrography and mineralogy of xenoliths ilmenite-phlogopite containing deformed and granular peridotites from the Udachnaya-Eastern pipe. The age of pholopite porphyroclast from the studied deformed xenoliths matches with age of phlogopite megacryst and itself hosted kimberlites from Udachnaya pipe indicating the following processes closed in time: 1) crystallization of the low-Cr megacryst association; 2) deformation of rocks on the mantle lithosphere - asthenosphere border during the kimberlite-forming cycle; 3) formation of protokimberlite melts.
Thapsigargin, inhibitor of sarco-endoplasmic Ca2+-ATPase, effectively suppresses the expression of S100A4 in human breast cancer cell line
Authors: Kotnova A. P. , Lyanova B. M. , Dukhanina E. A. , Portseva T. N. , Ilyin Yu. V. , Georgieva S. G. , Stepchenko A. G. , Pankratova E. V.
Published: June 2019

Thapsigargin, the SERCA ATPase inhibitor, effectively suppresses the expression of metastasis marker S100A4 in breast cancer cells MDA-MB231. It has been demonstrated that transcription of the S100A4 gene is controlled by Ca2+-signaling pathways. It has been shown that synthesis of S100A4 mRNA and protein in the MDA-MB231 cell line is effectively inhibited by thapsigargin at a concentration of 0.4-4 µM, while preserving cell survival. We assume that a change in gene transcription in response to the disruption of Ca2+ homeostasis plays a direct role in the remodeling of Ca2+-signaling pathways.
ANALISIS UMUR LAMPU PIJAR TERHADAP PENGARUH POSISI PEMASANGAN
Authors: Sultan Ahmad Rizal
Published: June 2019

Secara umum, tiap jenis lampu listrik memiliki umur sendiri. Namun karena berbagai faktor umur rata-rata belum tercapai lampu pijar tersebut sudah rusak (terjadi kerusakan dini). Terjadinya kerusakan dini pada lampu pijar dipengaruhi oleh faktor yang berbeda. Hasil penelitian menunjukkan umur rata-rata lampu pijar dipengaruhi oleh posisi pemasangan (antara ketiga posisi pemasangan   mempunyai karakteristik yang berbeda). Selain itu Posisi merupakan posisi terbaik karena mempunyai koefisien variasi lebih kecil daripada posisi   dan  . Serta kemampuan menyala lampu pijar  pada posisi  lebih lama  walaupun umur nyalanya sedikit lebih kecil dari pemasangan lampu pijar pada posisi.
PENGATUR KECEPATAN KIPAS ANGIN LISTRIK BERBASIS PULSE WIDTH MODULATION
Authors: Dermawan Dermawan
Published: June 2019

Teknologi dengan menggunakan sistem kendali kecepatan banyak digunakan dalam keseharian masyarakat. Salah satu peralatan rumah tangga yang menggunakan sistem ini adalah kipas angin. Pada alat ini digunakan sebuah kontrol untuk mengatur kecepatan kipas angin AC 220v melalui luaran PWM mikrokontroller. Luaran dari alat yang dibuat adalah kipas angin AC 220v/45 watt dengan ukuran baling-baling 6”. Pada proyek penelitian ini yang akan dibuat, pembahasan berfokus pada beberapa hal berikut ini, diantaranya luaran yang digunakan adalah kipas angin AC 220v/45 watt dengan ukuran baling-baling 6”, dan tampilan menggunakan sebuah tujuh ruas, alat yang dibuat menggunakan kecepatan minimal satu dan maksimal sembilan, serta pemrograman alat ini menggunakan bahasa C dengan pustaka IRremote.
ANALISIS PERBANDINGAN SISTEM SALURAN KABEL UDARA TEGANGAN MENENGAH (SKUTM) DAN SALURAN KABEL TANAH TEGANGAN MENENGAH (SKTM)
Authors: Salim Agus , Sultan Ahmad Rizal , Akmal Ahsan
Published: June 2019

Sistem Distribusi merupakan bagian dari sistem tenaga listrik. Sistem distribusi ini berguna untuk menyalurkan tenaga listrik dari sumber daya listrik besar (bulk power source) sampai ke konsumen. Penelitian ini bertujuan untuk menentukan perbandingan nilai daya aktif (P), daya reaktif (Q), dan daya semu (S) antara nilai praktik dan nilai teori pada SKUTM dan SKTM serta untuk menentukan besar selisih antara tegangan pengirim dan tegangan penerima pada SKUTM dan SKTM. Penelitian diperoleh dengan pengumpulan data-data yang dibutuhkan kemudian dibuatkan tabel dan grafik menggunakan aplikasi matlab R2013a kemudian menganalisis dengan menggunakan analisis deskriptif dan perhitungan berdasarkan teori. Selain aplikasi matlab R2013a, digunakan juga software ETAP 12.6.0 untuk melakukan simulasi. Kesimpulan dari penelitian ini yaitu hasil perbandingan nilai praktik dan teori antara daya aktif (P), daya reaktif (Q), dan daya semu pada SKUTM maupun SKTM tidak jauh berbeda. Selanjutnya hasil perbandingan selisih tegangan pengirim dan tegangan penerima kondisi tanpa kompensasi maupun dengan kompensasi pada kabel udara lebih besar dibandingkan kabel tanah.
SIMULASI KOORDINASI PROTEKSI PADA JARINGAN TRANSMISI MENGGUNAKAN SIMULATOR TRANSMISI
Authors: Naim Kurniawati
Published: June 2019

Penelitian ini bertujuan menghitung dan menganalisis penyetelan koordinasi rele porteksi sehingga sistem tidak terganggu. Luaran yang ingin dicapai yaitu penyetelan koordinasi rele sesuai dengan fungsinya. Metode yang digunakan dalam penelitian evaluasi  rugi daya dan jatuh tegangan adalah metode studi literatur, wawancara/interview dan metode analisa data. Dari data yang telah terkumpul, maka dilakukan pengelompokan data sesuai identifikasi permasalahannya sehingga diperoleh analisa dan pemecahan masalah yang efektif dan terarah. Data yang diperoleh akan dianalisa dan dihitung berapa settingan nominal rele yang bagus untuk jaringan transmisi kemudian membuat scenario untuk melihat koordinasi proteksinya. Percobaan ini menghasilkan enam scenario yaitu pertama dengan settingan arus yang sama tapi setting waktu main proteksi lebih cepat. Kedua, back up proteksi  dinonaktifkan dan main proteksi diaktifkan, Sebaliknya,ketiga, main proteksi  dinonaktifkan dan back up proteksi diaktifkan. Keempat, setting waktu main proteksi lebih cepat daripada back up proteksi. Lima, setting arus main proteksi lebih besar daripada back up proteksi. Sebaliknya, Enam, setting arus main proteksi lebih kecil daripada back up proteksi.
SISTEM PENGAMANAN JARINGAN ADMIN SERVER DENGAN METODE INTRUSION DETECTION SYSTEM (IDS) SNORT MENGGUNAKAN SISTEM OPERASI CLEAROS
Authors: Suhartono Suhartono , Patta Abd. Rahman
Published: June 2019

Jenis penelitian ini adalah penelitian R & D (Research And Development), yang bertujuan untuk membangun sistem monitoring keamanan jaringan admin server dengan basis sistem operasi adalah ClearOS. Metode yang digunakan dalam sistem monitoring keamanan jaringan admin server ini adalah dengan model 4D ( four-D model ). Model 4D (four-D model)terdiri dari beberapa tahapan – tahapan yaitu  pendefinisian, perancangan, pengembangan dan uji coba. Hasil penelitian ini adalah sebuah sistem pengamanan jaringan admin server yang memberikan kemudahan terhadap admin server untuk memonitor kinerja server, monitoring serangan yang dilakukan oleh hacker, attacker, dan intruder serta mampu mendeteksi dan mengatasi serangan SSH bruteforce dan FTP bruteforce.
Mathematical formulation of a new linear surface element for the modeling of axisymmetric magnetic field problems
Authors: Diaz Florez Guillermo A. , Mombello Enrique E. , Voss Stephan
Published: June 2019

There are currently two main trends in solving magnetic field problems, numerical methods, of which the Finite Element Method (FEM) is undoubtedly the most popular, and analytical methods, of which there is a great diversity of approaches. The main advantage of numerical methods is their flexibility in modeling complicated geometries; however, its calculation times are generally considerable. Analytical methods attain very short calculation times by sacrificing flexibility. This paper presents the mathematical formulation of a new linear surface element for the semi-analytical solution of axisymmetric magnetic field problems. The importance of this formulation is that it is capable of dealing with arbitrary geometries while retaining the flexibility of numerical methods with considerably shorter calculation times. The results of the application of the proposed formulation to a case study are presented in the validation section. The results obtained are compared with those calculated with FEM showing an excellent agreement between them.
McStas (i): Introduction, use, and basic principles for ray-tracing simulations
Authors: Willendrup Peter Kjær , Lefmann Kim
Published: June 2019

We present an overview of, and an introduction to, the general-purpose neutron simulation package McStas. We present the basic principles behind Monte Carlo ray-tracing simulations of neutrons performed in the package and present a few simple examples. We present the implementation of McStas, the status of the package and its use in the neutron community. Finally, we briefly discuss the planned development of the package.
Risk for Parkinson’s Disease in Patients with Behçet’s Disease: A Nationwide Population-Based Dynamic Cohort Study in Korea
Authors: Park Ho Youn , Lee Ju Hee , Lee Soo Young , Yu Dong Soo , Han Kyung-Do , Park Yong Gyu , Lee Young Bok
Published: June 2019

Background:

Although several studies have reported a correlation between Behçet’s disease (BD) and Parkinson’s disease, this association has not yet been clarified.

Objective:

To determine the risk of Parkinson’s disease in patients with BD.

Methods:

BD patients ( n = 17,179; mean age, 51.12±8.09 years; male, 34.95%) without known previous diagnosis of Parkinson’s disease were selected from the Korean National Health Insurance Database between 2010 and 2013. An age- and gender-matched control population of individuals without BD was randomly sampled at a ratio of 3:1 ( n = 34,575). Both cohorts were followed for development of Parkinson’s disease until 2015.

Results:

Among a total of 11,525 BD patients, 50 (0.43%) developed Parkinson’s disease, whereas only 51 among the 34,575 individuals in the non-BD group developed Parkinson’s (0.15%, P < 0.0001). The incidence of Parkinson’s disease was significantly higher in BD patients than in controls. In addition, during the follow-up period, patients with BD were more likely to be diagnosed with Parkinson’s disease than those in the non-BD group.

Conclusions:

BD patients had a higher risk of Parkinson’s disease compared to non-BD controls. Physicians should carefully monitor patients with BD for potential development of Parkinson’s disease.
Comparison of geometrical uncertainties in the radiotherapy for various treatment sites with two different immobilization marking methods
Authors: Pan Jing-Hui , Yu Dong-Dong , Song Qi-Bin , Ruan Chang-Li , Fu Jing-Guo , Wu Bing , Ma Guang-Dong , Wang Lu-Zhou , Lei Yu , Han Guang
Published: June 2019

OBJECTIVE:

The skin marking method (SMM) and bow-form-ruler marking method (BFRM) are two commonly used patient marking methods in mainland China. This study aims to evaluate SMM and BFRM by comparing the inter-fraction setup errors from using these two methods together with vacuum cushion immobilization in patients underwent radiotherapy for different treatment sites.

MATERIALS AND METHODS:

Eighteen patients diagnosed with pelvic, abdominal and thoracic malignant tumors (with 6 patients per treatment site) were enrolled in this prospective study. All patients were immobilized with vacuum cushion. Each patient was marked by both SMM and BFRM before computed tomography (CT) simulation. Target location was verified by cone beam CT images with displacements assessed prior to each sampled treatment session. The localization errors in three translational and three rotational directions were recorded and analyzed.

RESULTS:

Images from 108 fractions in 18 patients produced 324 translational and 324 rotational comparisons for SMM and BFRM. The setup errors of all treatment sites showed no difference in two marking methods in any directions ( p > 0.05). In subgroups of treatment site analysis, SMM significantly lessened the lateral and yaw setup errors compared to BFRM in the pelvic sites (0.39±1.85 mm vs –1.28±1.13 mm, p < 0.01 and –0.19±0.59° vs –0.61±0.59°, p < 0.05). However, in the abdominal subgroup, BFRM was superior to SMM for reduced vertical errors (0.17±2.73 mm vs 2.28±3.16 mm, p < 0.05). For the underweight or obese patients (with Body Mass Index, BMI < 18.5 or BMI≥24), SMM resulted in less yaw errors compared to BFRM (–0.05±0.38° vs –0.43±0.48°, p < 0.05). No significant difference between SMM and BFRM in setup errors of normal weighted patients (18.5≤BMI < 24) was observed for all three studied treatment sites.

CONCLUSIONS:

This study shows no significant difference in patient setup errors for various treatment sites between SMM and BFRM in general. SMM may be suitable for the pelvic tumor and patients with BMI < 18.5 or BMI≥24, while BFRM is recommended for the abdominal tumor sites.
EDITORIAL
Authors: Tim Redaksi Jurnal Nfn
Published: June 2019

Sidang pembaca yang budiman dan yang kami hormati, kami segenap redaksi Jurnal TEKNODIK mengucapkan â€œSelamat Hari Raya Idulfitri 1440 H bagi segenap pembaca yang merayakannya dan mohon maaf lahir bathin. Di samping itu, kami juga merasa bersyukur dan bergembira dapat menemui pembaca melalui Jurnal TEKNODIK Volume 23 Nomor 1, Edisi Juni 2019 sesuai dengan waktu terbit yang ditetapkan.
Classification of the Priority of Auditing XBRL Instance Documents with Fuzzy Support Vector Machines Algorithm
Authors: Sheu Guang-Yih
Published: June 2019

Concluding the conformity of XBRL (eXtensible Business Reporting Language) instance documents law to the Benford's law yields apparently different results before and after a company's financial distress. These results bring an idea of finding fraudulent documents from the inspection of financial ratios since the unacceptable conformity implies a large likelihood of a fraudulent document. Fuzzy support vector machines models are developed to implement such an idea. The dependent variable is a fuzzy variable quantifying the conformity of an XBRL instance document to the Benford's law; whereas, independent variables are financial ratios. Nevertheless, insufficient data are available to define any membership function for describing the fuzziness in independent and dependent variables, but the interval factor method is introduced to express that fuzziness. Using the resulting fuzzy support vector machines model, it is suggested that the price-to-book ratio versus equity ratio may be used to classify the priority of auditing XBRL instance documents. The misclassification rate is less than 30 \%. In conclusion, a new and promising application of fuzzy support vector machines algorithm has been found in this study.
An Empirical Analysis of the Displacement Effect of TFSAs on RRSPs
Authors: Berger Leslie , Farrar Jonathan , Zhang Lu
Published: June 2019

The tax-free savings account (TFSA), introduced in 2009, was intended by the Canadian government to provide an alternative catchment for savings in addition to registered retirement savings plans (RRSPs). However, little empirical evidence exists regarding the impact of saving in TFSAs on saving in RRSPs. To investigate this issue, we conduct empirical analysis, using data from Statistics Canada's Longitudinal Administrative Databank, which contains annual TFSA and RRSP contributions for a sample of 20 percent of all Canadian taxfilers. We find evidence of a displacement effect of TFSAs on RRSPs: every 1 percent increase in a TFSA contribution reduces an RRSP contribution by approximately 0.4 percent. Our findings have implications for Canadians' ability to self-fund their retirement, as well as for the Canadian government's ability to generate future tax revenues.
Planification fiscale personnelle : GILTI — Introduction au GILTI et à son application aux actionnaires américains de sociétés canadiennes
Authors: Pereira Michael , Gandhi Pinaki , Park Hena
Published: June 2019

Le nouveau régime du revenu mondial à faible taux d'imposition tiré de biens incorporels (global intangible low-taxed income [GILTI]), instauré dans le cadre de la réforme fiscale américaine de 2017, attribue le revenu de certaines sociétés étrangères excédant un rendement arbitraire de 10 pour cent aux biens incorporels et assujettit ce revenu à l'impôt américain à payer par certains particuliers actionnaires américains dans l'année où le revenu est gagné. Le présent article explique comment les citoyens américains qui résident au Canada et sont assujettis aux règles sur le GILTI peuvent contrer les effets négatifs du régime au moyen du choix visé à l'article 962 de l'Internal Revenue Code. Le choix permet aux particuliers actionnaires d'être imposés au taux d'imposition américain des sociétés de 21 pour cent (au lieu du taux d'imposition maximal des particuliers de 37 pour cent), de demander une déduction de 50 pour cent de l'inclusion du GILTI et de demander des crédits pour impôt étranger pour une partie des impôts canadiens des sociétés qui ont été payés. Grâce à ce choix, l'impôt mondial combiné des sociétés et des particuliers à payer peut demeurer essentiellement le même qu'avant l'adoption du GILTI. Par contre, une gestion moins efficace de l'exposition au GILTI peut donner un résultat très différent.

Avec de bons conseils et informations, les dispositions relatives au GILTI pourront représenter, pour certains actionnaires américains, « beaucoup de bruit pour rien ». Cependant, pour les actionnaires américains des sociétés qui paient le taux d'imposition des petites entreprises, il y a un petit coût fiscal à l'inclusion du GILTI pour conserver l'avantage du report. Pour tous les actionnaires américains de sociétés canadiennes, il reste des questions qui n'ont pas été abordées et qui ajoutent complexité et incertitude à la préparation des déclarations de revenus américaines de ces particuliers.
Personal Tax Planning: GILTI—Introduction to GILTI and Its Application to US Shareholders of Canadian Corporations
Authors: Pereira Michael , Gandhi Pinaki , Park Hena
Published: June 2019

The new global intangible low-taxed income (GILTI) regime, introduced as part of the 2017 US tax reform, attributes income of certain foreign corporations in excess of an arbitrary 10 percent return to intangible assets and subjects such income to US tax on a current basis for certain US individual shareholders. This article explains how US citizens resident in Canada who are subject to the GILTI rules may effectively manage the adverse implications of the regime by utilizing an election under section 962 of the Internal Revenue Code. The election allows individual shareholders to be taxed at the US domestic corporate tax rate of 21 percent (instead of a maximum personal tax rate of 37 percent), claim a deduction for 50 percent of the GILTI inclusion, and claim foreign tax credits for a portion of Canadian corporate taxes paid. With this election, a combined corporate and personal global tax liability may remain mostly consistent with the pre-GILTI era. On the other hand, if the GILTI exposure is not appropriately managed, the result is significantly different.

With proper advice and reporting, for some US shareholders, the GILTI provisions may be a case of "much ado about nothing." However, for US shareholders of corporations that pay the small business rate, there is a small tax cost to the GILTI inclusion for maintaining the benefit of deferral. For all US shareholders of Canadian corporations, there are still some unaddressed issues that add complexity and uncertainty to the preparation of those individuals' US income tax returns.
Disputing Denied Downward Transfer-Pricing Adjustments
Authors: Sandler Daniel , Watzinger Lisa
Published: June 2019

This article considers the appropriate forum for disputing a denied downward transfer-pricing adjustment under subsection 247(10) of the Income Tax Act ("the ITA"). It begins by describing various scenarios in which a request for a downward transfer-pricing adjustment may arise, examines the delegation to officials at the Canada Revenue Agency (CRA) of the authority to grant the adjustment, and outlines the CRA's administrative practice on when to grant such adjustments. It then explores whether the Federal Court or the Tax Court of Canada is the appropriate forum to adjudicate a denied downward transfer-pricing adjustment.

For disputes under the ITA, the division of jurisdiction between the two courts is generally well defined. The Tax Court has the exclusive jurisdiction to determine the correctness of an assessment whereas the Federal Court has the exclusive jurisdiction to review discretionary decisions of the minister of national revenue or officials at the CRA to whom the minister's powers have been delegated. This jurisdictional divide is less clear for disputes in respect of a denied downward transfer-pricing adjustment.

Subsection 247(10) is the only provision in the ITA under which the correct determination of a taxpayer's income is subject to ministerial discretion. The exercise of ministerial discretion suggests that the appropriate forum to dispute a denied transfer-pricing adjustment is the Federal Court. However, subsection 247(11) specifies that the mechanisms for resolving all transfer-pricing disputes under part XVI.1 of the ITA are through the objection and appeal process in part I of the ITA. The language of subsection 247(11), coupled with its legislative history, the restrictions on the Federal Court's jurisdiction, and practical considerations regarding transfer-pricing disputes, all suggest that the Tax Court is the appropriate forum to consider a denied downward transfer-pricing adjustment. Historical case law from the Exchequer Court supports this conclusion.

However, there are scenarios in which a denied downward transfer-pricing adjustment may not result in a notice of assessment being issued, and therefore no clear right of appeal to the Tax Court may exist. To ensure that the Tax Court has the jurisdiction to review all denied downward transfer-pricing adjustments, and not only those that result in an assessment, the authors recommend that part XVI.1 of the ITA be amended to include language requiring the minister to issue an assessment in all cases in which a downward transfer-pricing adjustment is denied.
Re: Delivering Bad News: When My Patient Was My Own Mother
Authors: Abbasi Zahra , Karbakhsh Mojgan
Published: June 2019

NA
Prescribing Oral Contraceptives in Women With Breast Diseases: A Matter of Concern for the Gynecologist
Authors: Alipour Sadaf , Eskandari Amirhossein
Published: June 2019

Background: The association of exogenous steroid hormones with breast malignancy has long been, and still is, a subject of investigation. This manuscript, as part of a series of articles about effects of exogenous sex hormones on breast conditions, reviews the adverse and beneficial effects of oral contraceptives in various entities separately: benign and malignant breast diseases, women with risk factors of breast cancer, and the general population. Methods: We first reviewed international clinical guidelines about the subject. Then, a comprehensive search of the literature was carried out using appropriate keywords. Clinical trials, population-based or cohort studies, nested case-control studies, and narrative/systematic reviews were reviewed and relevant data were extracted. Results: Oral contraceptives are contraindicated in women with current or previous breast cancer. Among women at high risk for breast cancer, those with preceding chest wall irradiation should not use pills, while these are allowed in cases with BRCA mutations or with a positive family history of breast cancer. Oral contraceptives may be beneficial for benign breast diseases. For low-risk woman, pills either pose no risk or may induce a very mild risk for breast cancer.Conclusion: Oral contraceptives are generally safe regarding breast diseases except in breast cancer patients or high-risk women, especially those with a history of chest wall irradiation.
Nanomedicine, A New Therapeutic Strategy in Breast Cancer treatment
Authors: Esfandiari Neda , Taherian Amirali
Published: June 2019

Background: As cancers, especially breast cancer, have become the most lethal and concerning subject, new methods to promote therapies and achieve better results are strongly essential. Nanotechnology has offered a new approach to advocate the strategies being used and to vanquish their impediments. This article provides a review of the nanomaterials used most recently, mainly in breast cancer, for more effective and specific treatment.

Methods: Documents were found in PubMed and Google Scholar using “nanomaterials” and “breast cancer” as the main keywords. Additionally, each individual nanomaterial with “liposomes”, “polymeric NPs”, “dendrimers”, “quantum dots”, “virus like nanoparticles” and “magnetic NPs” keywords were searched and selected after assessments such as publishers, journals impact and their relativities to the subject of the review. 

Results: Six frequently used nanoparticles in breast cancer treatment including liposomes, polymeric NPs, dendrimers, VLPs, quantum dots, and magnetic NPs were selected to be discussed in this review. They all showed correlative results such as promoting drug maintenance, hydrophilicity, and accumulation in the tumor site by their specific cell targeting system and high cellular uptake. Each of these NPs has unique properties and disadvantages and therefore many in vitro and in vivo experiments have been carried out.

Conclusion: Extensive research into in nanotechnology in medicine, especially in cancer, suggests that nanotechnology could be the dawn of a new era in cancer treatment and imaging.
Breast Conserving Surgery and Intraoperative Electron Radiotherapy (IOERT) Among Cases of Ductal Carcinoma In Situ
Authors: Nafissi Nahid , Farahzadi Athena , Zeinali Zahra , Mirzaei Hamidreza , Moayeri Hasan , Salati Azam , Akbari Mohammad Esmaeil
Published: June 2019

Background: Ductal Carcinoma In Situ (DCIS) which has recently been renamed into Ductal Intraepithelial Neoplasia (DIN), is a malignant cell proliferation without invasion to basement membrane of ducts or lobules of breast. DCIS consists 20-30% of newly diagnosed breast cancers in some Western countries due to higher diagnosis resulting from screening by mammography. Relative Risk (RR) of invasive ductal carcinoma is 8-10 times in DCIS, although high grading lesions and positive or close surgical margins are two important predictive factors in DCIS recurrences. The adjuvant radiotherapy has decreased the rate of ipsilateral local recurrence about 60%. In this article, we evaluated the recurrence rate as DCIS as well as invasive breast cancer in patients with DCIS undergoing breast conserving surgery (BCS) and intraoperative electron radiotherapy (IOERT).Methods: Data were derived from Cancer Research Center database from 38 pure DCIS cases who had received intraoperative radiation therapy between 2012–2017. Intraoperative electron radiotherapy (IOERT) was performed according to Iran's intraoperative radiation therapy consensus.Results: The median age of the patients was 55 years and median histological lesion size was 1.8 centimeters. Number of extracted lymph nodes had a median of 1 and all extracted nodes were negative. Hormonal therapy was performed in 42.1% of patients. IOERT was done as radical full exposure for 86.9% of cases and as boost dose for 13.1% of cases, who needed to complete radiotherapy by external beam. One case in the group received boost dose and 4 cases in the group received full dose had recurrence. The median follow-up of patients was 31 months. Pathology of recurrence was reported as DCIS in 3 cases and invasive breast cancer in 2 of them.Conclusion: There is not a lot of data on the effectiveness of IOERT in DCIS management. Although there are not large number of cases in our study, the local recurrence (13.1%) was only event in our study with 31 months median follow up with no contralateral metastasis, distant metastasis, or death.
PENGARUH PAJAK PERTAMBAHAN NILAI TERHADAP PENERIMAAN PAJAK
Authors: Hartanti Hartanti , Pujiwidodo Dwiyatmoko , Angel Nikita Sianturi Devi
Published: June 2019

Pajak Pertambahan nilai muncul karena adanya faktor-faktor produksi disetiap jalur produksi dalam menyiapkan, menghasilkan, menyalurkan dan memperdagangkan barang atau pemberian jasa kepada para konsumen. Penelitian ini bertujuan untuk menguji pengaruh / kontribusi Pajak Pertambahan Nilai  terhadap Penerimaan pajak. Metode yang digunakan adalah metode kuantitatif dengan menggunakan uji statistik yaitu Uji korelasi, koefisien determinasi, uji t dan persamaan Regresi. Data berupa Pajak Pertambahan Nilai (X) dan Penerimaan Pajak (Y) pada KPP pratama Jakarta-Duren Sawit tahun 2013-2017. Hasil Penelitian uji korelasi menunjukkan terdapat hubungan yang kuat, positif dan siqnifikan antara Pajak Pertambahan Nilai dengan Penerimaan Pajak. Uji determinasi  menunjukkan Penerimaan Pajak dipengaruhi oleh penerimaan Pajak Pertambahan Nilai sebesar 79,4%% dan sisanya sebesar 20,6% dipengaruhi oleh faktor-faktor lain yang tidak diteliti. Uji t menunjukkan ada pengaruh yang signifikan antara Pajak Pertambahan Nilai dengan Penerimaan Pajak, sedangkan uji persamaan regresi menunjukkan ada persamaan regresi signifikan yang terbentuk yaitu Y = 4,107+ 0,849X antara kedua variabel tersebut.
PENGARUH SIZE, WEALTH, INTERGOVERMENTAL REVENUE DAN BELANJA MODAL TERHADAP KINERJA PEMERINTAH DAERAH
Authors: Aminah Iim Nur , Afiah Nunuy Nur , Pratama Arie
Published: June 2019

Penelitian ini bertujuan untuk memberikan bukti empiris tentang pengaruh Size, Wealth, Intergovernmental Revenue dan Belanja Modal terhadap Kinerja Penyelenggaraan Pemerintah daerah dengan menggunakan LPPD sebagai sumber utamanya.Populasi yang digunakan dalam penelitian ini adalah pemerintah daerah yang ada di wilayah Jawa Barat tahun 2014-2016 yang terdiri dari 18 Kabupaten, 9 Kota dan 1 Provinsi. Pengambilan sampel penelitian dengan menggunakan metode purposive sampling, dan diperoleh  sebanyak 84 pengamatan, setelah dilakukan analisis terdapat 9 data yang tidak sesuai kriteria, sehingga total sampel yang diteliti sebanyak 72 pengamatan. Data yang terkumpul dianalisis dengan menggunakan Program SPSS dengan menggunakan uji asumsi klasik, kemudian dilakukan uji hipotesis dengan metode analisis regresi linier berganda dan terakhir uji statistik.Hasil penelitian menunjukkan bahwa variabel size, wealyh, intergovernmental revenue dan belanja modal berpengaruh positif terhadap kinerja penyelenggaraan pemerintah daerah.
El metabolismo social de las Cadenas Cortas de Comercialización: Una aportación a la sostenibilidad desde el trabajo colectivo
Authors: Saralegui Díez Pablo
Published: June 2019

El metabolismo social está resultando una herramienta integral para tanto analizar las transiciones históricas alimentarias, como las propuestas contestatarias al Sistema Agroalimentario Global en el que nos encontramos. No obstante, principalmente se han desarrollado trabajos desde una perspectiva biofísica e histórica, siendo necesario analizar las nuevas cadenas agroalimentarias conformadas por movimientos sociales alimentarios, tanto por su actualidad como por la necesidad de contribuir a mejorar su funcionamiento. En esta contribución se pretende formular una categorización de las distintas cadenas agroalimentarias (agro-)ecológicas que funcionan en la ciudad de Madrid, integrando para ello una visión sobre el trabajo colectivo a lo largo de la cadena corta, y como pilar fundamental de su estructura y mantenimiento a lo largo del tiempo.
Iniciativa para la Integración Regional Sudamericana (IIRSA-COSIPLAN): neoextractivismo y emergencia de Brasil y China en América Latina
Authors: Escalante Moreno Helios
Published: June 2019

La inserción de América Latina en la economía mundial se ha caracterizado históricamente por la extracción de recursos naturales y materias primas dirigidos los países centrales. Recientemente el relativo declive de la hegemonía de Estados Unidos ha permitido dejar espacio para la emergencia de otras fuerzas. Entre ellas destacan Brasil como potencia regional y China como potencia internacional, necesitados de recursos naturales para el crecimiento de sus economías.

Todas estas tendencias se reflejan en la articulación del megaproyecto IIRSA-COSIPLAN (Iniciativa para la Integración Regional Sudamericana), basado en la construcción de infraestructuras, especialmente corredores de transporte y energéticos, destinadas a facilitar dicha extracción y exportación de recursos. La historia de este megaproyecto está vinculada con los cambios políticos vividos en América Latina en la primera década del siglo XXI y los distintos procesos de integración regional, marcados por el paso de gobiernos abiertamente neoliberales a los llamados gobiernos progresistas.
Evaluation of Pumping HR (Human Resources) Model-Based Training Program on Human Resources Development at Bogor Agricultural University (IPB)
Authors: Ramly Amir Tengku
Published: June 2019

The evaluation study of pumping HR model-based HRD training program at Institut Pertanian Bogor (IPB) is a program evaluation to see the program effectiveness against the professionalism and performance of employees. This research is evaluative research with a model frame of CIPP of Stufflebeam, with evaluation components: context, input, process, and product. Pumping HR model-based HRD training program at IPB is a beneficial program for employment and personal, which have an impact on performance. Considering the context, this program supports the goal of Human Resource Development of IPB. Considering the input, this program is designed tailored to the need of Human Resource in IPB to (1) reinforcement of the values and beliefs, (2) strengthen competence, and (3) encourage successful behavior in terms of responsibility, professionalism, and friendliness in working. Considering the process, this program is preferred and fun for participants and considering the product (output and outcome) this program provides benefits and clear impacts for the performance of the employee.
Arbitrage Pricing Theory Model Application on Tobacco and Cigarette Industry in Indonesia
Authors: Ichsani Sakina , Susanti Neneng , Suhardi Agatha Rinta
Published: June 2019

The purpose of this study was to applicant the Arbitrage Pricing Theory model in the tobacco and cigarette industry listed on the IDX. The APT model in this study uses macroeconomic variables consisting of exports, inflation, exchange rates, GDP and economic growth. Object of this research is companies listed on the Indonesia Stock Exchange in the period 2012-2017 using monthly periods, which is Gudang Garam Tbk., Handjaya Mandala Sampoerna Tbk., and Bentoel International Investama Tbk. This study uses quantitative methods and analysis will be used with regression analysis methods and data processed using Eviews 10. The results of the study show that there are simultaneous effects between the variables of exports (X1), inflation (X2), exchange rates (X3), GDP (X4), and economic growth (X5) on stock returns (Y). There is a significant positive effect between economic growth on stock returns, while there is a significant negative effect between inflation on stock returns and GDP on stock returns. While exports do not affect the stock returns of the tobacco and cigarette industry as well as the exchange rate does not affect stock returns. Suggestions for investors are if investors are going to invest in the tobacco and cigarette industry, then investors should pay attention to the macroeconomic conditions that affect stocks, while for companies can minimize the risks that might occur through agreements between the destination countries for cigarette sales.
INOVASI DESAIN LURIK PEDAN PADA ACESORIES INTERIOR SEBAGAI PENGEMBANGAN PRODUK UNGGULAN
Authors: Badriyah Siti
Published: June 2019

Lurik Pedan adalah produk kekayaan potensi daerah yang merupakan warisan budaya yang sangat berharga sebagai produk unggulan kota Klaten. Produktivitasnya hingga kini masih tersisa meskipun beberapa banyak
yang sudah gulung tikar pengusaha pada industry ini. Di era global yang sangat kompetitif industri kain tradisional harus berbenah dengan berbagai alternative untuk mempertahankan eksistensinya. Melalui inovasi desain
sebagai pengembangan produk akan memberikan solusi untuk meningkatkan daya saing dan mempertahankan kelestarian produk warisan tersebut. Lurik dengan beragam motif yang khas bisa dimanfaatkan melalui
pengembangan inovasi desain pada segmen acesoris interior. Dengan memperhatikan karakter spesifik Lurik akan tetap ditampilkan secara khas melalui ide desain sehingga dapat memberikan stimulus bagi pengrajin
untuk mengembangkan ketrampilan secara sederhana namun tetap mempertahankan kekhasannya.
Kata kunci: Lurik Pedan, inovasi desain , acesories interior, produk unggulan.

Lurik Pedan is a local product that becomes a valuable cultural heritage as a seeded product of Klaten. The productivity still can be found eventhough some producers have closed their industries. In this very competitive global era, industry of traditional textilehas to move to the various alternates in order to keep their existences. Design innovation as the product development will provide solutions to increase competitiveness and keeping the preservation of heritage product.Lurik with various special motives can be used through the development of design innovation on interior accessories.The specific character of Lurik will surely and specifically presented through the design ideas so that it gives stimulus to the pengrajin to mengembangkan ketrampilan sederhana by preserving its characteristic.
Keywords: Lurik Pedan, design innovation, interior assesories, seeded product.
SENI LUKIS KARIKATUR KARYA GM. SUDARTA
Authors: Budiyono Jimin , Kartika Dharsono Sony
Published: June 2019

“Seni Lukis Karikatur Karya GM. Sudarta.”ini memfokuskan permasalahan pada bagaimana latar belakang seni lukis karikatur GM. Sudarta, mengapa seni lukis GM. Sudarta bergaya karikatural dan bagaimana bentuk estetik seni lukis karikatur karya GM. Sudarta.Tujuan penelitian ini untuk memahami dan menjelaskan latar belakang seni lukis karikatur karya GM.Sudarta, memahami dan menjelaskan seni lukis GM. Sudarta yang bergaya  karikatural,  memahami  dan menjelaskan  serta  menganalisa  estetika  seni  lukis  karikatur  GM. Sudarta.Metode atau langkah-langkah penelitian ini menggunakan metode kualitatif. Lokasi penelitian di studio lukis GM.Sudarta Cisarua, Bogor Jawa Barat. Data yang diperoleh melalui observasi, wawancara dan dokumentasi (arsip). Analisis data menggunakan interaksi analisis dan interpretasi analisis dengan pendekatan kritik seni Dharsono Sony Kartika, untuk mengetahui makna estetiknya menggunakan teori estetika Monroe Beardsley.Hasil penelitian menunjukkan kepeduliannya rasa cinta bangsa seorang seniman (GM.Sudarta) kepada masyarakat, bangsa dan negara (Indonesia) yang baru dilanda krisis moral, penuh aib korupsi dan keadilan yang belum ditegakkan, dengan teriakan bahasa rupa “kita belum terlambat” masih ada waktu untuk perbaikan.

Kata kunci: Latar belakang, Karikatural, Estetika.
SIRAMAN SEBAGAI INSPIRASI PENCIPTAAN KARYA BUSANA TAPESTRI
Authors: Novilasari Ima
Published: June 2019

Siraman adalah salah satu prosesi pokok pernikahan adat Jawa yang mengandung falsafah di dalamnya, yaitu agar calon pengantin membersihkan diri dan hati, sehingga semakin mantap dan yakin untuk melangsungkan pernikahan di keesokan harinya. Momen siraman memotivasi penulis untuk mengekspresikan apa yang dialami menjadi karya busana tapestri. Melalui siraman, penulis membangun suasana dengan simbol-simbol bersifat abstrak, kemudian dikorelasikan dengan pengalaman-pengalaman sosial penulis menjelang pernikahan. Tahap di mana penulis harus mulai menentukan sikap, menentukan pilihan, memantapkan hati untuk menghadapi kehidupan dan tanggung jawab baru. Penulis berusaha menyampaikan wujud keagungan tentang prosesi siraman ke dalam karya busana tapestry. Bentuk-bentuk yang penulis ciptakan lebih mengambil makna dari unsur air siraman yang mengalir, yang diwujudkan dalam bentuk tali-tali yang menggantung ke bawah. Proses pembuatan tapestry penulis rasakan memiliki kesamaan atau kemistri batin dengan prosesi siraman, yaitu sama-sama sebagai sebuah proses yang tidak instan, memerlukan berbagai pertimbangan sebagai puncak pencapaian agar menghasilkan karya yang syarat dengan makna.

Kata kunci: Siraman, Sengalaman Sosial, Busana Tapestri.
ANALISIS GENDER FILM SALAH BODI MELALUI SEMIOTIKA CHRISTIAN METZ
Authors: Ali Mohammad Mahrush
Published: June 2019

ABSTRAK

 

Tulisan ini membahas mengenai gender yang terdapat pada film Salah Bodi melalui semiotika Metz. Pengamatan gender pada tokoh utama yaitu Farhan (Andien) dan Inong (Indra). Metode yang digunakan adalah kualitatif deskriptif, dengan teknik pengumpulan data yaitu telaah dokumen, studi pustaka, dan wawancara. Hasil dari tulisan ini adalah (a). Menghasilkan pemaparan dari analisis menggunakan semiotika Christian Metz pada film Salah Bodi. Delapan grand sintagmatiknya yaitu Autonomous Shot, Parallel Syntagma, Descriptive Syntagma, Alternating Syntagma, Scene, Episodic Sequence, dan Ordinary Sequence terkandung dalam film Salah Bodi kecuali sintagma kurung (Bracket Syntagma). Rangkaian sintagmatik Metz mengungkap adegan-adegan yang berdasarkan atas gender dan bertujuan untuk menunjukkan kepada penonton identitas gender dari tokoh film

 

(b). gender yang ditampilkan dalam film Salah Bodi memiliki kecenderungan berprilaku tersendiri seperti penampilan fisik, orientasi seksual, kebiasaannya, dan respon sosial dari masyarakat. Meskipun di akhir film ditunjukkan tokoh utama kembali ke kodrat aslinya. Dalam pembahasan ini juga didukung oleh argumen dari pelaku di luar film.

 

Kata kunci: Gender, Film Salah Bodi, Semiotika Christian Metz.

 

 

ABSTRACT

 

This paper discusses about gender contained in film Salah Bodi through Metz semiotics. The observation of gender is focused on the main characters, Farhan (Andien) and Inong (Indra). The method used is qualitative descriptive, with data collection techniques namely document review, literature study, and interview. The re-sults of this paper are (a). A presentation of the analysis using Christian Metz’s semiotics on the film Salah Bodi. The eight grand syntagmatic namely Autonomous Shot, Parallel Syntagma, Descriptive Syntagma, Alternating Syntagma, Scene, Episodic Sequence, and Ordinary Sequence are contained in the film Salah Bodi except Brackets Syntagm (Bracket Syntagma). The Metz’s syntagmatic sequence reveals the scenes based on gender and aims to show the audience the gender identity of the film character (b). the gender shown in the film Salah Bodi has a tendency to behave in isolation such as physical appearance, sexual orientation, habits, and social responses from the community, even though at the end of the film, the main character is shown back to his original nature. This discussion is also supported by the arguments from actors outside the film.

 

Keywords: Gender, Film Salah Bodi, Christian Metz Semiotics. .
Проблеми семантизації інформаційних ресурсів web для підтримки управління процесами оподаткування
Authors: Антоненко В. М. , Рогушина Ю. В. , Сьомка Н. К.
Published: June 2019

Проаналізовано проблеми, пов’язані з пошуком у Web інформації, що стосується оподаткуванням. Обґрунтовано доцільність використання семантичного пошуку, в якому застосовуються знання цієї предметної області. Для формалізації цих знань пропонується використовувати онтологію, яка містить основні терміни зі сфери оподаткування та зв’язки між ними. Ці знання використовуються для того, щоб визначити семантичну близькість між знайденими ресурсами та інформаційними потребами користувачів. Терміни онтології використовуються як основа для семантичної розмітки знайдених у процесі пошуку інформаційних ресурсів, що спрощує сприйняття інформації користувачами. Надаються рекомендації щодо вибору джерел для поповнення цієї онтології та метод здобуття онтологічних знань з природномовних ресурсів.
Between Technological Nostalgia and Engineering Imperialism
Authors: Fridlund Mats , La Mela Matti
Published: June 2019

Kuinka ulkomainen teknologia vaikuttaa maan teollistumiseen? Tätä kysymystä lähestytään ”teknologisen geopolitiikan” kautta tarkastelemalla näkemyksiä ja tulkintoja, joita suomalaiset tekniikan alan toimijat esittivät koskien Itä-Aasian suurvallan, Kiinan teknologiaa ja teollistumista. Artikkeli tutkii, kuinka keisarillista Kiinaa kuvattiin vuosina 1880–1912 Suomen ”teknisteollisen julkisuuden” keskeisellä foorumilla, suomalaisissa tekniikan alan aikakauslehdissä. Tämä artikkeli tuo uuden näkökulman Suomen tekniikan historian tutkimuskentälle kartoittamalla Suomen ja Kiinan suhdetta teknologian ja teollistumisen kautta. Se tarjoaa myös uuden tutkimusotteen digitaaliseen historiaan hyödyntämällä laadullista ja määrällistä haku- ja luentatapaa (”readsearch”) suomalaiseen tekniikan alan lehtiaineistoon. Tutkimus tuo esiin, kuinka kiinalainen teknologia ja teollisuus esiintyi lehdissä pääosin kahdella tavalla. Ensinnäkin teksteissä kuvattiin Kiinan varhaishistoriallista kehitystä ja perinteistä teknologiaa, mikä toimi ”nostalgisena” vastaparina tuoreimpien länsimaisten teollisten edistysaskeleiden kuvaukselle. Toiseksi käsiteltäessä uudempia aikakauden teknologioita lehtitekstien painopiste oli lännen vahvuuksissa, ja huomio kiinnitettiin Kiinan taloudellisen ja kaupallisen potentiaalin tai maan luonnonvarojen hyödyntämiseen. Artikkeli syventää tätä suurvaltapolitiikan näkökulmaa tarkastelemalla kahden suomalaisen insinöörin uraa läntisten siirtomaapyrkimysten palveluksessa ja valottaa siten aiemmin sivuun jääneitä, suomalaisia imperialistisia asenteita.
Konepajakulttuuri talteen – pelastusdokumentointia ja historian keruuta Hyvinkään lakkautettavalla konepajalla
Authors: Bergström Marina
Published: June 2019

VR Hyvinkään konepajan toiminta ajettiin yllättäen alas vuosien 2017-2018 aikana. Suomen Rautatiemuseo pelastusdokumentoi konepajan toimintaa viimeiset vuodet. Konepajan ja sen työntekijöiden merkitys rautatiekaluston kunnossapidon osaajina käy ilmi dokumentointiaineistosta, vaikka kaikkia toimintoja ei saatukaan tallennettua. Konepajatyöntekijöiden aktiivinen osallistuminen hankkeeseen rikastutti aineistoa merkittävästi.
Museo Ducati – Moottoripyöräilyn, teollisen muotoilun, insinööritaidon, brändirakennuksen ja yritysperinnön risteyksessä
Authors: Wuokko Maiju
Published: June 2019

Bolognassa sijaitsevan Ducati-moottoripyörien tehtaanmuseon Museo Ducatin arvostelu.