bluuebunny/crossref_metadata_2025 huggingface dataset:
Inspired by New Testament Priesthood
Authors: Harun Martin
Published: May 2019

This paper gives a detailed exegetical study of priesthood in the New Testament as gleaned from the Letter to the Hebrews, Paulâ€™s authentic letters, the Letters of later Pauline Communities, and the pastoral letters of Peter and Titus, with reference to the Gospels of Mathew and John as well as Revelation. Clearly for the New Testament writers, priesthood is not a cultic affair, but rather the living out of Christâ€™s one and only self-sacrifice for others. The author then contrasts the way in which ministries administered by a variety of people in the New Testament came to be accumulated in the ordained priesthood of the contemporary Catholic Church. Priests can actualise the priesthood as co-workers in a communion, realising their ministry in collaboration, both among themselves (ministerial priesthood), and with the laity (common priesthood), all contributing their specific gifts to the Body of Christ. And so Christ can be fully present and active in church and society. He concludes by noting that this vision is not far from the transforming vision of a community church as has been propagated by the Lumko Pastoral Institute.Â
There is a Great Need for Contextualisation in Southern Africa
Authors: Simango Daniel
Published: May 2019

The purpose of this article is to show the need for contextualisation in southern Africa. The author discusses the early missionary activities in Africa and the current problems that the African church faces and how these problems are linked with a lack of contextualisation of the Gospel.
The Conferment of Martyrdom: Retracing Bernard Mzeki’s Life from his Formative Years in the History of the Anglican Church in Zimbabwe until his Death (1890–2013)
Authors: Chawarika John , Duncan Graham Alexander
Published: May 2019

The conferment of martyrdom is a thorn in the flesh in the Anglican Church today. Bernard Mzeki has been commemorated annually since the late 1930s as a martyr in the Anglican Church of Zimbabwe. This is because Mzeki died a mysterious death on 18 June 1896 during the period of the first War of Liberation (Chimurenga) in Zimbabwe. Although there are other factors that might have contributed to the death of Mzeki, the church strongly believes that he died for his Christian faith. Whilst it is a fact that the Church of the Province of Central Africa does not have official, written criteria to confer martyr status, the mystics surrounding the death of Mzeki—as documented by Farrant (1966) and Broderick (1953)—authenticated his martyr status. In this regard, the martyrdom of Mzeki remained unique from the 1940s during the bishopric of William Paget, who accepted the unwritten “bottom-to-top” procedure in canonising his martyrdom. It is interesting to note that from the 1990s the church in Zimbabwe has had figures like Rev. Peter Wagner and Mrs Mandeya, who were presumed to have died for their faith, but were not recognised as martyrs. In the same period, Zimbabwean Bishops like Ishmael Mukwanda and others were advocating for an official, written procedure to canonise them. It is based on the above analysis that this article will examine
Basarwa in Botswana: The Role of Perceptions and Name Giving by other Population Groups in Enduring Poverty
Authors: Knoetze Johannes J , Hambira Rupert
Published: May 2019

This article is concerned with the way in which perceptions and name giving contribute to the socio-economic circumstances of a named group. The understanding of the Basarwa as a people in Botswana as well as how they have been perceived in history by â€œnew invadersâ€â€”including Christiansâ€”is used as an example. This article explores the influence of the attitudes or perceptions of â€œinvadersâ€ on the original inhabitants of the sub-continent. It is difficult to address the topic of the Basarwa with any amount of certainty due to insufficient records, more particularly due to lack of any records written from the perspective of the Basarwa themselves. This article shows that perceptions about the Basarwa as well as the names given to them by â€œinvadersâ€ play a defining role in the enduring poverty of the Basarwa people in Botswana.
Karl Barthâ€™s RÃ¶merbrief: A Turning Point in Protestant Theology
Authors: Dreyer Wim A.
Published: May 2019

Karl Barthâ€™s theology presents itself as a paradigm shift during the early part of the 20th century. As time went on, the radical nature of his theology manifested in different ways. Not only did it start out as a critique of Protestant liberal theology, but it also transformed the understanding of the church, mission and basic reformed doctrines such as election. This was met by vociferous protest, from liberal as well as more orthodox theologians. Despite all, PopeÂ Pius XII called Barth the greatest theologian since Thomas Aquinas. This contribution reflects on the first of Barthâ€™s major publications, his RÃ¶merbrief which first appeared in 1919. The point is made that Barthâ€™s RÃ¶merbrief could be regarded as an important turning point in the history of Protestant theology. The context of the RÃ¶merbrief is discussed as well as some of Barthâ€™s early theological views present in it, illustrating the radical break between Barth and the liberal theology of the Modern Era.
Reformation, Dissent and Diversity: The Story of Scotlandâ€™s Churches, 1560â€“1960
Authors: Duncan Graham
Published: May 2019

Book Review
Substâncias psicoativas: o uso entre universitários na região oeste de Santa Catarina
Authors: Kolhs Marta , Prado Geisa Percio do , Ascari Tania , Píccoli Sara , Lovison Robson , Bard Laura Caroline de Freitas , Vendruscolo Tainá Aparecida , Nogueira Raquel Ribeiro , Teston Bruna Paula , Colaço Nathalia , Hahn Eliana
Published: May 2019

Objetivo: Verificar o uso das substâncias psicoativas (SPAs) entre universitários de um Centro de Ensino Superior. Métodos: Optou-se por uma pesquisa quantitativa, epidemiológica transversal.  A coleta de dados deu-se por um questionário semiestruturado disponibilizado no Google Formulários; a análise dos dados quantitativos foi feita por meio de uma análise descritiva simples. Participaram da pesquisa 357 universitários dos cursos de enfermagem, engenharia de alimentos, engenharia química e zootecnia. Resultados: Os resultados apontaram que o consumo de substâncias psicoativas por parte desse segmento populacional é maior, quando comparado a população geral; o álcool apareceu como o mais consumido tanto pela quantidade de pessoas quanto nos cursos pesquisados e pela frequência nos últimos três meses, seguida do tabaco e da maconha. O número maior de consumidores está entre as idades de 18 a 24 anos. Quanto à idade em que experimentaram algumas das substâncias pela primeira vez, verificou-se que ocorreu entre os 12 e 17 anos. Conclusão: Os dados apontaram um consumo significativo de substâncias psicoativas, em especial para uso do álcool, tabaco e da maconha. Os resultados também indicaram uso variado de outras drogas, ressaltando uma tendência a experimentação por curiosidade típica da idade e/ou do grupo social.
A autoestima e o comportamento suicida em estudantes universitários: uma revisão da literatura
Authors: Silva Daniel Augusto da
Published: May 2019

Objetivo: Compreender as relações entre a autoestima e o comportamento suicida em estudantes universitários. Métodos: Trata-se de estudo de revisão narrativa da literatura, onde o autor interpreta e analisa a literatura científica conforme seu julgamento crítico. Este estudo foi realizado de forma não sistemática, com coleta de dados nas bases de dados científicas gratuitas disponíveis, em dezembro de 2018, com leitura na íntegra e análise crítica. Resultados: Na universidade são enormes as diferenças observadas em estudantes que possuem baixa e alta autoestimas. O risco do comportamento suicida se torna real na presença da baixa autoestima. Identifica-se na universidade um local de possibilidade para ocorrência e desenvolvimento de baixa autoestima com consequente comportamento suicida. Conclusão: Conclui-se que é real a necessidade de desenvolvimento de ações preventivas e de práticas específicas que visem a recuperação da saúde emocional dos estudantes universitários.
Prevalência da AIDS em idosos no centro-oeste brasileiro
Authors: Da Silva Amanda Tallita , Parreira Ana Luiza Barros , Machado Carolina de Araújo , Fonseca Daniel Cavalcante , Carmo Jéssica Silva do , Barbosa Mariana de Lima , Guerra Heloísa Silva
Published: May 2019

Objetivo: Analisar a prevalência de AIDS na população idosa do Centro-Oeste, no período entre janeiro de 2008 e dezembro de 2017, além de fornecer dados e informações que possibilitem a elaboração de medidas de promoção da saúde que sejam efetivas para a prevenção dessa moléstia na população estudada. Métodos: Trata-se de um estudo descritivo, por meio da análise dos casos de AIDS registrados no Centro-Oeste brasileiro entre janeiro de 2008 e dezembro de 2017, considerando-se as variáveis: faixa etária, sexo e categoria de exposição. Os dados foram coletados na base de dados do Departamento de Informática do Sistema Único de Saúde. Resultados: Os casos de AIDS em idosos representaram 4,59% do total na região e período analisados. O maior número de casos deu-se por relação heterossexual em homens. Conclusão: Há um número considerável de idosos sexualmente ativos, mostrando que o estigma de população assexuada precisa ser desconsiderado, e é necessário criar ações em saúde direcionadas a essa faixa etária.
Pré-Natal de alto risco: dados sociodemográficos e intercorrências durante a gravidez
Authors: Silva Joyce Driely Carvalho , Filha Francidalma Soares Sousa Carvalho , Silva Marcus Vinicius da Rocha Santos da , Silva Emilia Assunção Carvalho , Santos Janderson Castro dos
Published: May 2019

Objetivo: Analisar as características sociodemográficas e as intercorrências ocorridas com gestantes em Pré-natal de Alto risco em um município situado no nordeste brasileiro. Métodos: Trata-se de uma pesquisa avaliativa, do tipo exploratória, com abordagem quantitativa. Realizada com 95 gestantes, no período de março a setembro de 2017.  Os dados foram organizados em um programa estatístico (SPSS) em seguida tabulados, transformados em tabelas e posteriormente feita a análise e interpretação dos mesmos com base na literatura produzida sobre o tema. Resultados: Averiguou-se que a maioria das gestantes (67,4%) está na faixa etária entre 25 e maior ou igual a 36 anos; 67,3% são casadas ou mantém união estável; 57,9% tinham ensino médio completo; 50,5% estavam desempregadas. As principais intercorrências identificadas foram: hipertensão arterial/DHEG (16,8%) abortamento habitual (11,6%), idade superior a 35 anos (10,5%) ou inferior a 15 anos (9,5%). Foi percebido que 91 (95,8%) das gestantes tiveram acompanhamento com enfermeiro, 67 (70,5%) com médico e 38 (40%) com médico ultrassonografista. Conclusão: O principal motivo da presença das gestantes no pré-natal de alto risco foi hipertensão arterial que é reconhecida como uma das principais complicações que levam o risco as gestações, destacou-se também o abortamento habitual e idade superior a 35 anos.  Notou-se ainda a insuficiência de profissionais na atenção a uma parte dessas pacientes, visto que essas gestantes necessitam de um acompanhamento multiprofissional.
Entre Teoria e Prática – Estágio Básico em Psicologia Social e Comunitária: um relato de experiência
Authors: Miranda Conceição de Maria Melo , Lacerda Gisela Chaves , Oliveira Iana Monteiro de , Sousa Jardson de Andrade , Bezerra Lisiane Costa , Santos Renan Oliveira , Conceição Pedro Wilson Ramos da
Published: May 2019

Objetivo: Relatar a vivência acerca do Estágio Básico em Psicologia Social e Comunitária que teve como principal alvo fortalecer vínculos através do trabalho em equipe com os jovens do CRAS Mutirão/João Viana, promovendo a cooperação entre os jovens do equipamento, trabalhando a criatividade e o raciocínio e proporcionando a integração do grupo. Métodos: O presente relato trata-se de uma prática de estágio básico vivenciada em um dos CRAS da Cidade de Caxias-MA. Essa prática foi realizada no período de setembro a novembro de 2018. Resultados e Discussão: O Estágio Básico é uma oportunidade para os acadêmicos saírem dos muros do Centro Universitário e colocarem em prática o que aprenderam em sala de aula e torna-se enriquecedor para a comunidade e para o CRAS, pois o momento foi oportuno para potencializar a importância da figura do Psicólogo na Assistência Social e minimizar dúvidas sobre o fazer do Psicólogo na Política de Assistência Social, tendo em vista a visão holística do ser humano que a Psicologia proporciona. Por meio de um Projeto de Intervenção promoveu-se a construção do conhecimento, propondo atividades diferenciadas, com promoção da troca de experiências e socialização entre usuário e usuário, estagiários e usuários, estabelecendo entre todos um ambiente de consideração, aprendizagem e respeito. Conclusão: Ao longo de todo estágio foram avaliadas todas as atividades desenvolvidas, observando por meio destas o vínculo estabelecido pelos usuários em cada momento proposto, bem como o cuidado às dificuldades e facilidades apresentadas na realização de cada tarefa.
Investigation of the influence of extreme floods on the stability of protective dams (using the example of Hanoi city)
Authors: Dinh T. H. , Fomenko I. K. , Vazkova O. E. , Sirotkina O. N.
Published: May 2019

According to the territorial development plans of the city of Hanoi, there is a need to build a new dam system to ensure the normal functioning of the riverside areas. Therefore, the solution of the problem of analyzing the causes of the loss of stability of the of dam slopes protecting the city from floods is of particular relevance. When assessing the possibility of dam failure as a result of a landslide process, the most important indicator is the appearance of cracks in the body of the dam. The possible mechanisms of loss of stability of the dam slopes as a result of changes in the hydrological situation are considered, their rationale based on the results of mathematical modeling is given. The studies used a “geotechnical” approach to estimating pore pressure values, which is new in Russian practice. This approach, without excluding the need to perform hydrogeological modeling, makes it possible to assess the stability of the dam slopes when the level of flood waters changes. The generalized engineering-geological model of the lithotechnical system (LTS) of the dam can be represented as the following scheme: at the base of the LTS lies an aquifer, represented by sands of various grain sizes and flowing sandy loams, which is overlapped by low-permeable loamy and clayey soils. Two scenarios for the violation of the stability of the dam slope are considered: when the groundwater level rises during the period of extreme flood; due to the rapid drawdown of the level of flood waters. By the methods of mathematical modeling it is proved that the decrease in the stability coefficient occurs in both cases. Thus, it is shown that the collapse of the dam slopes is possible both when the groundwater level rises during the flood period and during a sharp decrease after the end of the flood. At the same time, in the first case there will be a slide of the slopes falling in the direction “from the river”, and in the second — “to the river”. This fact must be taken into account when developing measures to strengthen the slopes of existing dams, as well as when designing a new dam system in Hanoicity.
Regulatory framework of projects for determining the boundaries of the flood zones and current issues
Authors: Varentsova N. A. , Nikiforov D. A. , Granich P. S.
Published: May 2019

Problems of flooding existed at all times inRussia, but they acquired significant proportions only from the 20th century due to the spontaneous development of river floodplains by entire settlements. Such a city planning policy led to annual multimillion disaster damage, in the role of which the usual flood period often acts. In 2014, according to the experience of developed countries, Government Resolution № 360 was adopted to reduce hydroecological risks for the population, capital construction projects and territories exposed to the negative and dangerous effects of water. It defines the requirements for the territories and the procedure for establishing the boundaries of the zones of flooding within the river floodplains. The work is based on the requirements of water, land and city planning legislation. However, the strictly fixed rules for carrying out this work, as well as the standard technical task for projects haven’t been developed. It leads to randomness in the performance of work and significant problems when coordinating with the Roshydromet authorities. For this reason, and on the basis of 4 years of experience working with projects, the authors attempted to highlight the main requirements of current regulations and laws in the development of projects for determining the boundaries of flooded areas in terms of hydrometeorology work. Structuring the requirements of codes of practice and linking them with the basic definitions of the Water and City Planning Code leads to an understanding of the work execution algorithms and should remove most of the questions and comments on the draft defining the boundaries of flooded areas, as well as ensure reliable fixing of the boundaries of zones with special conditions of territory use in the unified state register real estate to ensure the safety of the population and economic objects.
Assessment of the effect of atmospheric pressure on the level and ground waters flow
Authors: Lavrov S. A. , Markov M. L.
Published: May 2019

The problem of understanding the interaction of river and ground water waters is intimately bound to questions of formation and unloading of ground waters in river network. The analysis of the previous researches showed that change of atmospheric pressure affects on the water level in observation wells and water discharge of springs. However, the mechanisms of this influence still weren't completely opened. For the solution of this task the complex laboratory, field and theoretical researches including overseeing by a drain, ground water level, atmospheric pressure and air pressure in an unsaturated (vadose) zone were conducted. On the basis of the conducted researches regularities the connecting size of change of ground water level and a drain of ground water waters with atmospheric pressure were received. As a result of generalization field and laboratory researches it was shown that the crucial role in formation of these regularities is played by the area located over a mirror of ground waters with the isolated interstitial air.

With an increase in atmospheric pressure, the volume of interstitial air decreases, and at pressure drop volume increases. It, in turn, leads to change in the level and a flow of ground waters. The settlement formula for numerical assessment of variability of level ground depending on atmospheric pressure (barometric efficiency) and degree of air isolation was received from it in an unsaturated zone. As an indicator of isolation, a characteristic is used such as the volume of interstitial air involved in the inflow (outflow) of water into a measuring well or watercourse and not having direct contact with the atmosphere. Research results showed that, in addition to gravitational force in the movement of ground water and the formation of ground water inflow of rivers and lakes, another force plays a certain role - the pressure difference between atmospheric air and air in the unsaturated zone above the aquifer.
Лікувально-діагностична тактика при рідинно-кістозних утвореннях підшлункової залози
Authors: Boyko V. V. , Lykhman V. M. , Shevchenko O. M. , Merkulov A. O. , Polikov G. O.
Published: May 2019

Мета. Розроблення лікувально–діагностичної тактики при рідинно–кістозних утвореннях підшлункової залози.
Матеріали і методи. Дослідження проведено щодо 48 хворих з гострим деструктивним панкреатитом, ускладненим рідинно–кістозними утвореннями. З діагностичною метою виконували пункцію під контролем ультразвукового дослі- дження з подальшим мікробіологічним та морфологічним дослідженням отриманого аспірату.
Результати. Вибір методики залежить від ефективності втручання, яка ґрунтується на вивченні ультразвукової карти- ни досліджуваної зони до та під час втручання, а також у ході динамічного дослідження після операції.
Висновки. Використовуючи в комплексній діагностиці морфологічний метод дослідження, можливо в ранні строки диференціювати рідинно–кістозні утворення як ускладнення гострого деструктивного панкреатиту та визначити лі- кувальну тактику.
Вплив біліопанкреатичного шунтування в модифікації Hess–Marceau на показники ліпідограми у хворих з морбідним ожирінням та дисліпідемією
Authors: Todurov I. M. , Perekhrestenko O. V. , Kosiuchno S. V. , Kalashnikov O. O. , Plehutsa O. I.
Published: May 2019

Мета. Вивчити вплив біліопанкреатичного шунтування (БПШ) у модифікації Hess–Marceau на показники ліпідограми у хворих з морбідним ожирінням та передопераційною дисліпідемією.

Матеріали і методи. В основу даного дослідження покладено дані клінічного обстеження та результати хірургічного лікування 100 хворих з морбідним ожирінням, яким було виконано БПШ у модифікації Hess–Marceau. Чоловіків було 40, жінок – 60. Середній вік пацієнтів становив (45 ± 8,2) року.

Результати. Лабораторні маркери переважно атерогенних фенотипів дисліпідемії до операції зафіксовано у 75 (75%) хворих. Середній рівень загального холестерину знизився з (6,14 ± 0,9) до (3,7 ± 0,7) ммоль/л, тригліцеридів – з (1,98 ± 0,9) до (1,12 ± 0,4) ммоль/л, регресія коефіцієнта атерогенності – з (3,9 ± 0,9) до (2,3 ± 1,1) через 60 міс після виконання метаболічного втручання (р < 0,05). Показники ліпідограми нормалізувались у 87,0%, покращились – у 13,0% пацієнтів.

Висновки. БПШ в модифікації Hess–Marceau є високоефективною методикою корекції дисліпідемії у хворих з мор-бідним ожирінням.
Віддалені результати лікування хворих з ішемічною кардіоміопатією із застосуванням стовбурових клітин пуповинної крові
Authors: Gabriyelyan A. V.
Published: May 2019

Мета. Порівняльний аналіз віддалених результатів трансплантації стовбурових клітин пуповинної крові (ТСКПК) та хірургічної реваскуляризації у хворих з ішемічною кардіоміопатією (ІКМП).

Матеріали і методи. Проаналізовано віддалені результати лікування 113пацієнтів з хронічною серцевою недостатністю на тлі ІКМП. У 38 (33,6%) пацієнтів було виконано ізольоване коронарне шунтування, у 35 (31,0%) - стентування коронарних артерій, у 20 (17,7%) - хірургічну реваскуляризацію було доповнено ТСКПК. Окрему групу склали 20 (17,7%) хворих, яким проводили тільки консервативну терапію. Термін спостереження становив 12 міс.

Результати. Через 6 міс після ТСКПК у хворих з ІКМП фракція викиду лівого шлуночка зросла з 24,8 до 33,3% (р < 0,05), рівень попередника натрійуретичного пептиду (proBNP) знизився на 51,6% (з 499,0 до 257,5 пг/мл). Досягнутий ефект зберігався впродовж 12 міс спостереження. Холтерівський добовий моніторинг електрокардіограми, проведений через 3, 6 та 12 міс після ТСКПК, не показав достовірного збільшення ризику виникнення фатальної аритмії.

Висновки. Застосування ТСКПК у комплексі лікування хворих з ІКМП поліпшує прогноз серцево-судинної смертності, знижує прояви серцевої недостатності, достовірно поліпшує якість життя і скоротливу функцію міокарда.
Склеротерапія під контролем ультразвукового дослідження в лікуванні венозних мальформацій обличчя
Authors: Galych S. P. , Artemenko M. O. , Hyndych O. A.
Published: May 2019

Мета. Дослідження сучасних можливостей використання черезшкірної склеротерапії під контролем ультразвукового дослідження в лікуванні венозних мальформацій обличчя.

Матеріали і методи. У відділенні мікросудинної та пластичної хірургії протягом 2016 – 2017 рр. проведено обстежен- ня та лікування методом склеротерапії 12 хворим з венозними мальформаціями. Жінок було 7, чоловіків – 5. У 5 пацієн- тів мальформації локалізувались в області щоки (жувальний м'яз), у 5 – в області верхньої або нижньої губи, у 2 – в об- ласті нижньої третини обличчя та шиї.

Результати. У 4 пацієнтів спостерігали повне склерозування мальформації, у 3 – склерозування більше половини ді- аметра мальформації протягом 3 – 6 тижнів, у 5 – склерозування менше половини діаметра мальформації протягом 3 – 12 тижнів.

Висновки. Склеротерапія під контролем ультразвукового дослідження є ефективним та безпечним методом лікуван- ня венозних мальформацій обличчя.
Особливості морфологічних змін в оцінці ефективностінеоад’ювантної таргетної терапії у хворих з локалізованимнирково–клітинним раком
Authors: Voylenko O. A. , Nepomnyaschy V. M. , Stakhovskyi O. E. , Vitruk Yu. V. , Kononenko O. A. , Pikul M. V. , Semko S. L. , Stakhovsky E. O.
Published: May 2019

Мета. Визначити особливості морфологічних змін під впливом неоад’ювантної таргетної терапії (ТТ), проведеної хворим з локалізованим нирково-клітинним раком (НКР).

Матеріали і методи. Вивчено дані 58 пацієнтів з локалізованим НКР, яким проведено два блоки неоад’ювантної ТТ з визначенням об’єктивної відповіді на лікування, подальшим оперативним втручанням та патоморфологічним дослідженням.

Результати. Середній показник регресії пухлини (М ± SD) після проведення ТТ становив (20,5 ± 14,3)% (95% довірчий інтервал- ДІ 16 - 24,3). Оцінка регресії пухлини за шкалою RECIST 1.1: стабілізацію відмітили у 44 (75,9%) хворих; часткову регресію- у 14 (24,1%). Повної регресії чи прогресії процесу не спостерігали у жодного хворого. Середній показник регресії за навності 2-го ступеня градації за Фурманом становив (22,6 ± 14,4)% (95% ДІ 18,3 - 26,9); 3-го ступеняг радації за Фурманом - (17,1 ± 11,7)% (95% ДІ 7,3 - 26,9); 4-го ступеня градації за Фурманом - (3,8 ± 2,9)% (95% ДІ 1 - 8,5); оцінка за методом ANOVA: η2=0,13; power=0,72; p < 0,05. Середня частка некрозу пухлини під дією ТТ достовірно вище у хворих з частковою регресією. Кореляційної залежності тяжкості судинних змін та частки життєздатної пухлинної тканини від ступеня регресії НКР не виявлено.

Висновки. Під впливом неоад’ювантної ТТ у хворих з локалізованим НКР відбулася регресія пухлини в середньому на (20,5 ± 14,3)%. Низький показник регресії НКР у хворих з 4-м ступенем гістопатологічної градації ядер за Фурманом - (3,8 ± 2,9)%, який свідчить про низьку ефективність ТТ (оцінка за методом ANOVA: η2 = 0,13; power = 0,72; p < 0,05), можна використовувати як прогностичний маркер відповіді.
Оцінка ефективності антибіотикотерапії у внутрішньоартеріальному та внутрішньовенному режимах у хворих з місцево–розповсюдженим раком молочної залози
Authors: Bondar O. V.
Published: May 2019

Мета. Поліпшення безпосередніх та віддалених результатів лікування місцево–розповсюдженого раку молочної залози (МР РМЗ) шляхом акселерованої регресії перифокальних запальних змін за допомогою селективного внутрішньо- артеріального застосування антибіотиків, підвищення якості життя хворих.  
Матеріали і методи. До контрольної групи включено 47 (53%) хворих з МР РМЗ, яким як неоад’ювантну терапію проведено серію курсів селективної внутрішньоартеріальної поліхіміотерапії (СВАПХТ) із системним використанням антибіотикотерапії в режимі внутрішньовенного введення. До досліджуваної групи включено 42 (49%) хворих, яким як неоад’ювантну терапію проведено серію курсів СВАПХТ із регіональним використанням антибіотикотерапії в режимі внутрішньоартеріального введення.  
Результати. Використання регіонального введення антибіотиків у складі комплексної неоад’ювантної терапії разом із СВАПХТ позитивно впливає на лінійну та хронометричну регресію запальних змін навколо вогнища первинно не- операбельного МР РМЗ, що поліпшує соматичний та психологічний стан пацієнток на етапі неоад’ювантного лікування та підвищує якість їх життя.  
Висновки. Комплексний регіональний вплив на уражений орган має статистично підтверджений кращий ефект з яскравими холістичними рисами та демонструє адитивний синергізм окремих селективних методик.
Clinical study of morphological changes in the arterial blood supply of the testicle in children
Authors: Baibakov V. M.
Published: May 2019

Objective. Studying of clinical and morphological changes in the arterial blood supply of testicle in its surgical diseases and improvement of the surgical treatment tactics.

Materials and methods. In the morphological stage of the study, there was obtained the material from 71 preparations of testicle and epitesticle, which were taken while doing necropsy in men of a mature age (22 – 35 years old), also there were processed 38 preparations of membranes in dropsy testicle, taken in a life–time, as well as postoperative material (in non–complete obliteration of vaginal sprout of peritoneum), and 17 testicular biopsy specimens, obtained in infertile men, which were taken during surgical intervention on testis in pediatric patients.

Results. Introduction of the innovative method and implementation of complex program for diagnosis and surgical treatment of the testicular diseases in children into clinical practice have permitted to improve a testicular blood supply and to reduce a risk of the ischemia occurrence.

Conclusion. Clinical and morphological changes in the arterial blood supply as a part of drainage systems of the testicle in its surgical diseases are expressed in development of total vascular spasm and ischemia, which were caused by narrowing of the arteries lumen, compensatory hypertrophy of the muscle layers of arterial wall, thickening of basal membranes, leading to increase in the number of blood vessels, sclerotic changes in stroma of spermatic cord, deformation of the ductus deferens.
Роль микробиологического обследования в диагностике и лечении перипротезной инфекции
Authors: Ankin N. L. , Petryk T. M. , Potochilova V. V. , Solodarenko S. A. , Ladyka V. A.
Published: May 2019

Цель. Определение оптимальной тактики микробиологического обследования пациента с перипротезной инфекци- ей (ППИ) путем оценки достоверности результатов бактериологических исследований в пред– и послеоперацион- ном периоде.
Материалы и методы. На базе Ортопедо–травматологического центра Киевской обласной клинической больни- цы на протяжении 2016 – 2018 гг. обследованы 32 пациента с подозрением на наличие ППИ. Во время предопераци- онной подготовки всем пациентам провели бактериологическое исследование, в ходе которого их разделили на две группы: 1–я – 23 пациента, которым проводили бактериологическое исследование посевов из свищевого хода; 2–я – 9 пациентов, которым осуществляли пункционный забор материала, так как свищевое отверстие у них отсутствовало.
Результаты. Из 147 предоперационных посевов у 83 (56,5%) определены грамположительные кокки; у 49 (33,3%) – грамотрицательные палочки; рост микроорганизмов не определялся в 15 (10,2%) посевах. У 22 (68,7%) пациентов вы- делена монокультура, у 10 (31,3%) –два и больше микроорганизмов.
Выводы. Диагностика ППИ является сложной и требует мультидисциплинарного подхода, предполагающего тесное сотрудничество ортопедов и микробиологов.
Первый опыт клинического применения устройства механической фиксации Aptus HeliFix во время эндоваскулярного протезирования брюшной части аорты
Authors: Furkalo S. N. , Khokhlov A. V.
Published: May 2019

Первый опыт клинического применения устройства механической фиксации Aptus HeliFix во время эндоваскулярного протезирования брюшной части аорты
Soberanía alimentaria: impacto socioeconómico de la asociatividad de productores de arroz
Authors: Bonilla Loor Karen Fernanda , Bonilla Loor Mario Javier , Sornoza Zambrano Willian Oswaldo , Solórzano Zambrano Liceth Janina
Published: May 2019

El arroz es un producto básico y principal en la dieta alimenticia de los ecuatorianos, no obstante, existe una diferencia de precios entre el productor y el intermediario, que lo vende al consumidor final. La presente investigación se realizó con el objetivo de evaluar la situación económica y social de los productores de arroz que se encuentran asociados en la Parroquia de Charapotó mediante una encuesta estructurada con preguntas cerradas de opción múltiple. Finalmente se evidenció que la asociatividad por parte de los agricultores generó un efecto positivo en la productividad del arroz y contribuyo a establecer un precio justo por el cereal, generando una mejor calidad de vida de los arroceros y sus familias en aspectos de educación, salud, vivienda principalmente.
Diversity and Species Composition of the Macrobenthic Invertebrates in Sürgü Stream (Malatya, Turkey)
Authors: KOŞAL ŞAHİN Serap , ZEYBEK Melek
Published: May 2019

The study was carried out on Sürgü Stream, located in Malatya Province (Turkey), and aimed to determine the diversity and species composition of macrobenthic invertebrates. Six stations were determined on the stream and macrobenthic invertebrates were taken seasonally. As a result, 34 taxa belonging to five classes were detected; one of which belongs to Hirudinea, one of which belong to Arachnida, three to Gastropoda, five to Malacostraca and 24 to Insecta classes. Insecta was the most dominant group among the determined taxa. The Shannon Weaver Diversity Index and the Simpson Index showed that the lowest species diversity was observed at the third station while the highest species diversity was found at the second station. Also, UPGMA algorithm was used to show possible clustering relationships among the seven stations based on organisms. According to UPGMA analysis, the highest similarity value was observed between the first and second stations (87%), while the lowest similarity value was found between the second and fourth stations (13%). To date, there is no study on the determination of macrobenthic invertebrate fauna of Sürgü Stream. Therefore, all the identified taxa have been recorded for the first time for the study area.
The effects of climatic factors in forming increment of English oak (Quercus robur L.) In south regions of Belarus
Authors: Knysh N. V. , Yermokhin M. V.
Published: May 2019

Our research let identified the main climatic factors which impact on radial increment of oak trees on different forest conditions in South Belarus. We defined three regions (southwest, south and southeast) with different growth conditions and built six standardized master chronologies from 140 to 230 years long.

The results of correlation analysis of standardized chronologies showed that response of oak trees to climate on floodplain and drained conditions differ significantly from oak trees growing in dry conditions. A regression model between oak treering width and climatic parameters was developed for different growing conditions. Response function showed that increment of oak trees in floodplain conditions is closely related with temperature at the beginning of the growing season. For trees that are growing in mesotrophic conditions the main importance is the regime of precipitation.
Computer simulation of aquaporin4-dependent water transfer across the hematoencephalic barrier
Authors: Basiakova K. V. , Titovets E. P.
Published: May 2019

A computational simulation of water transfer across the blood-brain barrier (BBB) has been carried out. In the developed model, AQP4 plays a kinetically limiting role in water transfer across the BBB. The effects of the AQP4 specific density changes and its polarized distribution have been studied in respect to the volumetric water transfer. It has been demonstrated that AQP4 density and polarization within the glial membranes enveloping the capillary can affect the volumetric flow and the sign of the water flux. The results might be used for elucidation of the pathogenic mechanism of cerebral edema and in development of the ways of pharmacological correction of the cerebral water metabolism disorders.
Aedes mercurator Dyar, 1920 as a new species of the mosquito (Diptera: Culicidae) in fauna of Belarus
Authors: Suslo D. S. , Khalin A. V. , Volkova T. V.
Published: May 2019

A new species of mosquitoes was recorded for the fauna of Belarus – Aedes mercuratorDyar, 1920 (Diptera: Culicidae). Fourth-stage larvae have been collected in 2018 on the territory of the Berezinsky Biosphere Reserve. Morphological and ecological characteristics of this species are given.
Production of male fertile interspecific hybrides between cultivated potatoes and valuable for breeding allotetraploid species Solanum stoloniferum
Authors: Levy A. V. , Ageeva A. S.
Published: May 2019

The germplasm of valuable for breeding wild allotetraploid potato species Solanum stoloniferumis rarely used because of pre- and postzygotic reproductive barriers with cultivated potatoes. One of the factors that complicate crosses between S. stoloniferum and S. tuberosumis unilateral incompatibility (UI).

Here, we present the results of application of original SvSv-lines for overcoming UI in crosses with S. stoloniferum and of generating male fertile hybrids derived from this species. SvSv-lines are F2 S. tuberosum dihaploid× S. verrucosum that are male fertile and have D/γ-type cytoplasm. Since they are hybrids on homozygous for Svgene from S. verrucosum, they do not form SvSv-lines and have the same ability for elimination of prezygotic incompatibility as this species.As a result of pollination seven SvSv-lines were pollinated by 26 accessions of S. stoloniferum and a lot of hybrid seeds have been produced.In spite of low percentage of germination (1.9 %), formed 40 seedlings of interspecific hybrids. The experiment on hybridization between SvSv-lines and S. stoloniferum has been reproduced with the accession PI205522 of the wild species, which had DNA markers of PVY and LB resistance genes and “sterile” type cytoplasm W/γ: 950 hybrid seeds and 12 viable seedlings were produced. The genome of the seedlings was doubled by colchicine treatment, which generated hexaploids (F1) that formed highly fertile pollen and set seeds from self-pollination. We were able to cross them as females with the variety Katahdin. Produced pentaploid hybrids (BC1) were readily backcrossed by potato variety Quarta. Seedlings of BC2 were then backcrossed by potato varieties as female and, some of them, as male parents. The substantial part of F1, BC1 and BC2 plants of interspecific hybrids were male fertile (produced a lot functionally fertile pollen).
Evaluation of TH and PHOX2B gene expression by real time PCR for diagnostic of bone marrow metastatic lesion in neuroblastoma patients
Authors: Kushniarova L. V. , Pakhomava I. V. , Praliaskouskaya I. V.
Published: May 2019

Despite on using the use of complex treatment, the survival of high risk neuroblastoma patients doesn’t exceed 50 % with relapse as the main cause of death. The bone marrow (BM) lesion and presence of minimal residual disease at various stages of therapy are key factors of poor outcome and high frequency of relapse. Real time PCR is the most promising method for detecting neuroblastoma cells in BM samples due to the high sensitivity and specificity, which achieved by combination of several molecular markers. In this study we developed a method for evaluation TH and PHOX2B expression for monitoring metastatic BM lesion in neuroblastoma patients. This method has high sensitivity (1·10–4) and specificity to tumor cells. Evaluation of TH and PHOX2B gene expression was performed for 67 children with neuroblastoma at the time of diagnosis. We demonstrated that patients with overexpression of these genes has significantly worse overall and relapse-free survival. So, the developed method can be used in clinical practice for evaluation BM lesion degree as well as for risk group stratification in neuroblastoma patients at the time of diagnosis.

Real time PCR is the most promising method for detecting neuroblastoma cells in BM samples due to the high sensitivity and specificity, which achieved by combination of several molecular markers. In this study we developed a method for evaluation TH and PHOX2B expression for monitoring metastatic BM lesion in neuroblastoma patients. This method has high sensitivity (1·10–4) and specificity to tumor cells. Evaluation of TH and PHOX2B gene expression was performed for 67 children with neuroblastoma at the time of diagnosis. We demonstrated that patients with overexpression of these genes has significantly worse overall and relapse-free survival. So, the developed method can be used in clinical practice for evaluation BM lesion degree as well as for risk group stratification in neuroblastoma patients at the time of diagnosis.
Structure of cenothic populations of Adenophora lilifolia (L.) A. DC. in the Southern Urals and the Middle Volga region
Authors: Ilina V. N. , Andreeva I. Z. , Abramova L. M.
Published: May 2019

The study of rare plants at the level of cenothic populations throughout the range greatly contributes to the identification of the features of their biology and ecology. We carried out the identification of the features of the age and spatial structure of the Adenophora lilifolia (L.) A. DC. cenothic populations in the ecological conditions of the steppe, foreststeppe zones of the Middle Volga (Samara region) and the Southern Urals (Republic of Bashkortostan), as well as the mountainous zone of the Southern Urals. Adenophora lilifolia is included in the Red Book of the Samara region (category 3 – a rare species).

The study of A. lilifolia populations was carried out in different years on the territory of specially protected territories of different rank. In determining the structure of cenothic populations, standard techniques were used. The studied cenopopulations are located on the fringes of oak-lime, birch, less often maple-linden or aspen forests, sparse forests or forest potholes. The total density of individuals varies from 0.8 to 4.2 specimens/m2. The mean values of the generative fraction in the populations are 81.1 %, the prevalent fraction is 19.3 %. The basic ontogenetic spectrum of A. lilifolia is characterized as centered. Although the share of generative individuals in all cenopopulations is high, the distribution by ontogenetic groups in the two regions differs. The average values of demographic indices indicate a fairly high stability of the species populations. Of the 14 investigated cenopopulations of A. lilifolia, according to the “delta-omega” criterion, most are mature, in addition, transitional and maturing are identified. In general, the state of the populations in the Southern Urals is fairly prosperous. All studied populations in the Samara region have a high anthropogenic load, and the number of individuals in specific habitats is low.
On rational solutions of two differential equations with а moving singular line
Authors: Zhang Bin-­Bin , Chen Yang , Martynov I. P.
Published: May 2019

The study is devoted to the analytical theory of ordinary differential equations. In the introduction, it is said that the object of investigation is nonlinear third-order autonomous differential equations with a moving singular line, and whose two-parameter rational solutions are known. The study aims to clarify how to obtain two-parameter rational solutions from the general solutions of these equations. In the analytical theory of differential equations, as a rule, nonlinear differential equations have negative resonances. Among these resonances is the resonance equal to –1 (trivial case). However, it is asserted in some of the researchers’ papers that the nature of these negative resonances has not been found until now. The equations only with non-trivial negative resonance arose the interest of researchers. And it appears that the rational solutions of the equations can be constructed by their negative resonances. In this paper, a necessary and sufficient condition is indicated, at which the two-parameter rational solution of the equation with a moving singular line can be obtained from its general solution.
Study of the microbiome species of the flowers phytophages based on the DNA-barcoding data
Authors: Panteleev S. V. , Baranov O. Yu. , Golovchenko L. A. , Konstantinov A. V. , Mozharovskaya L. V. , Dishuk N. G. , Timofeeva V. A. , Padutov V. E.
Published: May 2019

Based on the DNA-barcoding data, a molecular-genetic identification of the dominant microbiome species composition of the perennial floral plants phytophages was carried out. Various variants of species combinations in the microbiota–phytophagous system, as well as the ways of phytophagous transmission of pathogenic microflora have been identified.
Features of the space-time distribution of the seismic activity within the Soligorsk mining region
Authors: Aronov G. A.
Published: May 2019

Data on the earthquakes recorded in the Soligorsk mining area during the years 1983–2017 were used to investigate their distribution features both in the energy, and space-time characteristics. Based on the sketch maps of the epicenters and the graphs of the accumulated numerical values of the earthquakes the periods and areas of the repre sentative earthquakes were determined for each energy class К = 5, 6, 7, 8. A normalized graph of the earthquake recurrence was created.
High thermal conductivity silicon-carbide ceramics for large-size space optics
Authors: Grinchuk P. S. , Abuhimd H. , Akulich A. V. , Kiyashko M. V. , Solovei D. V. , Stepkin M. O. , Toropov V. V. , Shashkov M. D. , Khort A. A. , Liakh M. Yu.
Published: May 2019

The paper describes the important aspects of the developed technology for manufacturing silicon-carbide substrates for optical mirrors intended for future use in space applications. It is shown that the material with the best combination of thermophysical and mechanical properties (Maksutov’s criterion) among the known analogs used for making astronomical mirrors is obtained. The characteristics of a mirror made of a lightweight mirror substrate with a diameter of 205 mm are described, compared with the parameters of most known mirrors made of silicon carbide for various space missions and as proto types. It is shown that the produced substrate is characterized by a rather low specific gravity – 16.5 kg/m2, which is comparable with the indicators of the best world analogues.
Theoretical and methodological basis of megacluster development of agro-industrial complex
Authors: Gusakov E. V.
Published: May 2019

The local and world practice shows that clustering as a form of association of business entities for development of industrial and business activities is an important direction for development of agri-food sector, as well as the arrangement of territories based on efficient use of land, labor, material, technical and financial resources. The article dwells of studies of theoretical and methodological basis of megacluster development of agro-industrial complex. It has been determined that currently four possible concepts (paradigms) can be applied regarding agro-industrial complex (AIC): AIC as a self-sufficient system, AIC as a megacorporation, AIC as a specific market, AIC as a separate society. Study has been carried out and an integrated layout has been designed for arrangement and functioning of an integrated management system for agro-industrial complex sustainable development. Groups of factors determining stability of short-term and long-term development of agro-industrial complex as a megacluster are identified. A number of principles for sustainable functioning of agro-industrial complex as a megacluster were formed: Infrastructure balance, management system improvement, rational territorial and intrasectoral distribution of production, balanced agro-industrial production in terms of resources, etc. These principles and their interpretation have been formulated for agro-industrial complex as a megacluster for the first time. Their novelty consists both in aggregate selection, reflecting stable functioning of agro-industrial complex as a megacluster under new conditions, and in reflecting the most significant aspects of megacluster's activity being the main links in its sustainable functioning chain.