bluuebunny/crossref_metadata_2025 huggingface dataset:
Stigma Associated With Pelvic Floor Disorders
Authors: Cox Caroline K. , Schimpf Megan O. , Berger Mitchell B.
Published: October 2020

Objectives

Although the impact of stigma is known for women with urinary incontinence, it has not been well studied among the full spectrum of pelvic floor disorders. This study quantifies the level of stigma among women presenting for urogynecologic care and tests the hypothesis that stigma related to pelvic floor disorders results in a delay in care seeking for these problems.

Methods

Women presenting for new patient visits (N = 523) in university medical center–based urogynecology clinics completed 2 anonymous questionnaires (Stigma Scale for Chronic Illnesses 8-item version and Pelvic Floor Bother Questionnaire) before their visit. The Kruskal-Wallis test was used to compare the distributions of stigma scores. Logistic regression was used to model factors associated with a delay in seeking care. Spearman correlation was used to determine whether there was an association between stigma and bother scores.

Results

Median stigma score was significantly higher for those presenting with complaints of urine leakage (P = 0.015), accidental bowel leakage (P < 0.001), and constipation (P < 0.001) compared with women without these symptoms. Women presenting with accidental bowel leakage had the highest median stigma score, and those presenting with pelvic organ prolapse had the lowest. Total stigma score had a moderately positive correlation (r = 0.5, P < 0.001) with bother score. In a logistic regression model, higher stigma score was associated with a decreased likelihood of waiting 1 year or more to seek care (odds ratio = 0.92, 95% confidence interval = 0.86–0.98).

Conclusions

Pelvic floor disorders carry varying levels of stigma. Women who feel more stigmatized by pelvic floor disorders seem to seek care earlier.
Mesh Complication Rates Following Pelvic Radiation Therapy in Women With History of Synthetic Midurethral Sling Implantation
Authors: Painter Caitlyn E. , Geynisman-Tan Julia , Samant Navendu , Postlethwaite Debbie , Ramm Olga
Published: October 2020

Objective

To estimate the risk of mesh complications in women with and without subsequent pelvic and abdominal radiation therapy (RT).

Methods

We identified women within a large health care organization who underwent mesh-augmented surgery for pelvic floor disorders between 2008 and 2014 and subsequently received RT prior to 2018. We compared them to a randomly selected group of women who underwent similar mesh-augmented pelvic reconstructive surgery without RT in a 1:4 ratio. Mesh complications were identified through chart review corroborated with the ninth and tenth revisions of the International Classification of Diseases and Current Procedural Terminology codes for mesh complications. Mesh complications between groups were compared using survival analysis and Cox proportional hazards models.

Results

We identified 36 women with RT and compared them with 144 women without RT. Indications for mesh implantation and concomitant vaginal procedures were similar between the groups. The majority of mesh implants (94.4%) were midurethral slings. Twelve mesh complications (6.7%) were identified, with similar rates in the RT (8.3%) and no-RT (6.2%) groups (P = 0.65). The risk of mesh complications did not differ between groups when compared using the Cox proportional hazards model, controlling for age, body mass index, diabetes, menopausal status, and smoking (hazard ratio, 1.19; 95% confidence interval, 0.802–1.787).

Conclusions

There was no difference in the occurrence of mesh-related complications between women with and without RT. Abdominopelvic RT may not substantially increase the risk of mesh complications following placement of a synthetic sling for stress urinary incontinence. The need for future RT may only be a minor factor in counseling patients on the risks of mesh implants for pelvic floor disorders.
Effect of Initial Prednisone Dosing on Ocular Myasthenia Gravis Control
Authors: Shah Yesha S. , Henderson Amanda D. , Carey Andrew R.
Published: October 2020

Background:

Ocular myasthenia is an autoimmune condition that results in double vision or ptosis. It often requires treatment with prednisone for immunosuppression, but there have been no prospective trials to help clinicians determine ideal dosing.

Methods:

This was a retrospective study comparing myasthenia symptom control at 1 month between patients treated with a maximum daily equivalent dose of prednisone less than 20 mg (low-dose group) vs 20 mg or more (medium-dose group).

Results:

Thirty-nine patients were identified: 19 patients in the low-dose group with mean maximum daily dose of 10 mg and 20 patients in the medium-dose group with a mean maximum daily dose of 29 mg. The low-dose group had 75% controlled or significantly improved at 1 month, and the medium-dose group had 74% controlled or significantly improved at 1 month, P = 0.94. The overall seropositivity rate was 64%, with 84% of the antibody-positive group being controlled or significantly improved at 1 month and 57% of the antibody-negative group being controlled or significantly improved at 1 month, P = 0.07, and no difference in prednisone dosing between the 2 groups.

Conclusion:

Based on the results of this small retrospective study, it seems initial treatment for ocular myasthenia gravis with a mean maximum daily prednisone dose of 10 mg is similarly effective compared with mean maximum daily dose of 29 mg for control at 1 month.
Gazing Into the Crystal Ball: Calciphylaxis Causing Striking Retinal Vascular Calcification, Ocular Ischemic Syndrome, Crystalline Retinopathy, and Ischemic Optic Neuropathy
Authors: Cherayil Neena R. , Scoles Drew , Moran Anna M. , Elder David E. , Tamhankar Madhura A.
Published: October 2020

A 72-year-old woman with membranous glomerulonephritis and failed renal transplant on peritoneal dialysis presented with bilateral vision loss. She reported several months of diminishing right eye vision that worsened after cataract extraction. On presentation, visual acuity was hand motion in the right and 20/100 in the left eye with a right afferent pupillary defect. Confrontation visual fields were constricted bilaterally. Intraocular pressure was 23 in the right eye, and there was diffuse right eye central corneal opacity with iris neovascularization. Fundus examination revealed bilateral pale optic nerves with cotton wool spot inferior to the left optic disc and diffuse arteriolar whitening with crystalline deposits in the left macula. Given fundus appearance, concurrent ischemic optic neuropathy, and ocular ischemic syndrome, ocular calciphylaxis was suspected. The patient reported development of painful gluteal nodules a month prior, and biopsy revealed calcinosis cutis, a dermatopathologic finding on the spectrum of calcific vasculitides. Her vision continued to decline in both eyes with left eye vision of 20/400. Intravenous sodium thiosulfate through hemodialysis was started with initial improvement in left eye vision to 20/125, but subsequently declined despite treatment. Pathogenesis of systemic calciphylaxis is poorly understood but believed to result from upregulation of osteogenesis and decreased inhibition of vascular calcification in parathyroid axis dyscrasias due to end-stage renal disease. Excess serum calcium-phosphate deposits in blood vessels causing tissue infarction, most commonly in the skin. Prior case reports have described ischemic optic neuropathy mimicking giant cell arteritis and crystalline retinopathy with ocular ischemic syndrome separately. Treatment with empiric intravenous sodium thiosulfate and calcium chelation may preserve vision in some patients.
Compressive Optic Disc Edema and Contralateral Papilledema: Type 2 Foster Kennedy Variant Syndrome
Authors: Zehden Jason , Harish Bindiganavile Shruthi , Bhat Nita , Lee Andrew G.
Published: October 2020

A 43-year-old woman presented with progressive anosmia, self-neglect, and lethargy for 1 year. Brain MRI demonstrated a mass that was compressing the optic nerve in the right eye and had a significant mass effect and cerebral edema producing increased intracranial pressure. Examination revealed the patient to have a variant of Foster Kennedy syndrome involving ipsilateral compressive optic neuropathy with superimposed optic disc edema and contralateral papilledema.
Atom-by-atom analysis of sintering dynamics and stability of Pt nanoparticle catalysts in chemical reactions
Authors: Martin Thomas E. , Mitchell Robert W. , Boyes Edward D. , Gai Pratibha L.
Published: October 2020

Supported Pt nanoparticles are used extensively in chemical processes, including for fuel cells, fuels, pollution control and hydrogenation reactions. Atomic-level deactivation mechanisms play a critical role in the loss of performance. In this original research paper, we introduce real-time in-situ visualization and quantitative analysis of dynamic atom-by-atom sintering and stability of model Pt nanoparticles on a carbon support, under controlled chemical reaction conditions of temperature and continuously flowing gas. We use a novel environmental scanning transmission electron microscope with single-atom resolution, to understand the mechanisms. Our results track the areal density of dynamic single atoms on the support between nanoparticles and attached to them; both as migrating species in performance degradation and as potential new independent active species. We demonstrate that the decay of smaller nanoparticles is initiated by a local lack of single atoms; while a post decay increase in single-atom density suggests anchoring sites on the substrate before aggregation to larger particles. The analyses reveal a relationship between the density and mobility of single atoms, particle sizes and their nature in the immediate neighbourhood. The results are combined with practical catalysts important in technological processes. The findings illustrate the complex nature of sintering and deactivation. They are used to generate new fundamental insights into nanoparticle sintering dynamics at the single-atom level, important in the development of efficient supported nanoparticle systems for improved chemical processes and novel single-atom catalysis.

This article is part of a discussion meeting issue ‘Dynamic
in situ
microscopy relating structure and function’.
BCG vaccination induces enhanced frequencies of memory T and B cells and dendritic cell subsets in elderly individuals
Authors: Kumar Nathella Pavan , Padmapriyadarsini Chandrasekaran , Rajamanickam Anuradha , Bhavani Perumal Kannabiran , Nancy Arul , Jayadeepa Bharathi , Selveraj Nandhini , Kumar Dinesh , Renji Rachel Mariam , Venkataramani Vijayalakshmi , Tripathy Srikanth , Babu Subash
Published: October 2020

Background

BCG vaccination is known to induce innate immune memory, which confers protection against heterologous infections. However, the effect of BCG vaccination on the conventional innate and adaptive immune cells subsets is not well characterized.

Methods

We investigated the impact of BCG vaccination on the frequencies of T cell, B cell, monocyte and dendritic cell subsets as well as total antibody levels in a group of healthy elderly individuals (age 60-80 years) at one month post vaccination as part of our clinical study to examine the effect of BCG on COVID-19.

Results

Our results demonstrate that BCG vaccination induced enhanced frequencies of central and effector memory CD4+ T cells and diminished frequencies of naïve, transitional memory, stem cell memory CD4+ T cells and regulatory T cells. In addition, BCG vaccination induced enhanced frequencies of central, effector and terminal effector memory CD8+ T cells and diminished frequencies of naïve, transitional memory and stem cell memory CD8+T cells. BCG vaccination also induced enhanced frequencies of immature, classical and activated memory B cells and plasma cells and diminished frequencies of naïve and atypical memory B cells. While BCG vaccination did not induce significant alterations in monocytes subsets, it induced increased frequencies of myeloid and plasmacytoid DCs. Finally, BCG vaccination resulted in elevated levels of all antibody isotypes.

Conclusions

BCG vaccination was associated with enhanced innate and adaptive memory cell subsets, as well as total antibody levels in elderly individuals, suggesting its potential utility in SARS-Cov2 infection by enhancing heterologous immunity.
Characterization of Mycobacterium tuberculosis-specific Th22 cells and the effect of tuberculosis disease and HIV co-infection
Authors: Makatsa Mohau S. , Omondi F. Millicent A. , Bunjun Rubina , Wilkinson Robert J. , Riou Catherine , Burgers Wendy A.
Published: October 2020

The development of a highly effective tuberculosis (TB) vaccine is likely dependent on our understanding of what constitutes a protective immune response to TB. Accumulating evidence suggests that CD4+ T cells producing IL-22, a distinct subset termed ‘Th22’ cells, may contribute to protective immunity to TB. Thus, we characterized Mycobacterium tuberculosis (Mtb)-specific Th22 (and Th1 and Th17) cells in 72 individuals with latent tuberculosis infection (LTBI) or TB disease, with and without human immunodeficiency virus (HIV)-1 infection. We investigated the functional properties (IFN-γ, IL-22 and IL-17 production), memory differentiation (CD45RA, CD27 and CCR7) and activation profile (HLA-DR) of Mtb-specific CD4+ T cells. In HIV-uninfected individuals with LTBI, we detected abundant IFN-γ producing CD4+ T cells (median: 0.93%) and IL-22-producing CD4+ T cells (median: 0.46%) in response to Mtb. The frequency of IL-17 producing CD4+ T cells was much lower, at a median of 0.06%. Consistent with previous studies, IL-22 was produced by a distinct subset of CD4+ T cells and not co-expressed with IL-17. Mtb-specific IL-22 responses were markedly reduced (median: 0.08%) in individuals with TB disease and HIV co-infection compared to IFN-γ responses. Mtb-specific Th22 cells exhibited a distinct memory and activation phenotype compared to Th1 and Th17 cells. Furthermore, Mtb-specific IL-22 was produced by conventional CD4+ T cells that required T cell receptor (TCR) engagement. In conclusion, we confirm that Th22 cells contribute substantially to the immune response to TB. Depletion of Mtb-specific Th22 cells during HIV co-infection may contribute to increased risk of TB disease.
Quantifying Geographic Heterogeneity in TB Incidence and the Potential Impact of Geographically Targeted Interventions in South and North City Corporations of Dhaka, Bangladesh: A model-based Study
Authors: Shrestha Sourya , Reja Mehdi , Gomes Isabella , Baik Yeonsoo , Pennington Jeffrey , Islam Shamiul , Faisel Abu Jamil , Cordon Oscar , Roy Tapash , Suarez Pedro G. , Hussain Hamidah , Dowdy David
Published: October 2020

Background

In rapidly growing, high burden urban centers, identifying tuberculosis (TB) transmission hotspots and understanding potential impact of interventions can inform future control and prevention strategies.

Methods

Using data on local demography, TB reports, and patient reporting patterns in Dhaka South City Corporation (DSCC) and Dhaka North City Corporation (DNCC), Bangladesh, between 2010 and 2017, we developed maps of TB reporting rates across wards in DSCC and DNCC and identified wards with high rates of reported TB (i.e. “hotspots”) in DSCC and DNCC. We developed ward-level transmission models and estimated the potential epidemiological impact of three TB interventions: active case finding (ACF), mass preventive therapy (PT), and a combination of ACF and PT, implemented either citywide or targeted to high-incidence hotspots.

Results

There was substantial geographic heterogeneity in the estimated TB incidence in both DSCC and DNCC: incidence in the highest-incidence wards was over ten times higher than in the lowest-incidence wards in each city corporation. ACF, PT and combined ACF plus PT delivered to 10% of the population reduced TB incidence by a projected 7-9%, 13-15%, and 19-23% over five years, respectively. Targeting TB hotspots increased the projected reduction in TB incidence achieved by each intervention 1.4- to 1.8-fold.

Conclusions

The geographical pattern of TB notifications suggests high levels of ongoing TB transmission in DSCC and DNCC, with substantial heterogeneity at the ward level. Interventions that reduce transmission are likely to be highly effective, and incorporating notification data at the local level can further improve intervention efficiency.
Deinbollia onanae(Sapindaceae), a new, Endangered, montane tree species from the Cameroon Highlands
Authors: Cheek Martin , Onana Jean Michel
Published: October 2020

Deinbollia onanae(Sapindaceae-Litchi clade) is here formally named and characterised as a new species to science, previously known asDeinbollia sp. 2. Cameroon has the highest species-diversity and species endemism known in this African-Western Indian Ocean genus of 42 species.Deinbollia onanaeis an infrequent tree species known from five locations in surviving islands of montane (or upper submontane) forest along the line of the Cameroon Highlands. It is here assessed as Endangered according to the IUCN 2012 standard, threatened mainly by clearance of forest for agriculture. The majority of tree species characteristic of montane forest (above 2000 m alt.) in the Cameroon Highlands are also widespread in East African mountains (i.e. are Afromontane).Deinbollia onanaeis one of only a very small number of species that are endemic (globally restricted to) the mountain range. It is postulated that this new species is in a sister relationship withDeinbollia oreophila,which is a frequent species of a lower (submontane) altitudinal band of the same range. It is further postulated that seed dispersal is or was by frugivorous birds, potentially turacos, alternatively by primates such as Preuss s monkey.
Activity of acetic acid and sodium bicarbonate to inhibitAsergillus ochraceuson culture media and detoxification of ochratoxin A in poultry diet
Authors: Hussein Halima Z. , Al-Baldawy Mneer Saed , Hamed Rakib. A.
Published: October 2020

The study was conducted to evaluate the activity of acetic acid and sodium bicarbonate to inhibitAspergillus ochraceuson culture media and reduce ochra toxin A in poultry diet. It was found that addition of acetic acid into PDA medium 0.2%, 0.5% and 4% could reduce Aochraceusgrowth by 90.22%, 98.77and 100%, respectively. Similar reduction inA ochraceusgrowth was obtained on PDA containing sodium bicarbonate that attained to 81%, 91.5%, and 100% at 4%, 2% and 5% concentrations, respectively. Results showed that addition of acetic acid at 0.5% and sodium bicarbonate at 1% could reduce ochre A mycotoxin by 65.7% and 43.6%, respectively in the first month and then reached to 100% in the second month for the two compounds.
A novel equilibrative nucleoside transporter 1 inhibitor alleviates Tau-mediated neurodegeneration
Authors: Chang Ching-Pang , Chang Ya-Gin , Chuang Pei-Yun , Nguyen Thi Ngoc Anh , Chou Fang-Yi , Cheng Sin-Jhong , Chen Hui-Mei , Jin Lee-Way , Carvalho Kevin , Huin Vincent , Buée Luc , Blum David , Liao Yung-Feng , Lin Chun-Jung , Chern Yijuang
Published: October 2020

Tau hyperphosphorylation favors the formation of neurofibrillary tangles and triggers the gradual loss of neuronal functions in tauopathies, including Alzheimer’s disease. Herein, we demonstrated that chronic treatment with an inhibitor (J4) of equilibrative nucleoside transporter 1 (ENT1), which plays a critical role in controlling adenosine homeostasis and purine metabolism in the brain, exerted beneficial effects in a mouse model of tauopathy (Thy-Tau22, Tau22). Chronic treatment with J4 improved spatial memory deficits, mitochondrial dysfunction, synaptic plasticity impairment, and gliosis. Immunofluorescence assays showed that J4 not only reduced Tau hyperphosphorylation but also normalized the reduction in mitochondrial mass and suppressed the abnormal activation of AMP-activated protein kinase (AMPK), a pathogenic feature that is also observed in the brains of patients with tauopathies. Given that AMPK is an important energy sensor, our findings suggest that energy dysfunction is associated with tauopathy and that J4 may exert its protective effect by improving energy homeostasis. Bulk RNA-seq analysis revealed that J4 also mitigated immune signature associated with Tau pathology including C1q upregulation and A1 astrocyte markers. Collectively, our findings suggest that identifying strategies for normalizing energy and neuroimmune dysfunctions in tauopathies through adenosinergic signaling modulation may pave the way for the development of treatments for Alzheimer’s disease.
Heavily burned wood from wildfires is less likely to provide functionality in streams
Authors: Vaz Pedro Gonçalves , Merten Eric C. , Robinson Christopher T. , Pinto Paulo
Published: October 2020

Increasingly severe forest fires are recruiting more heavily burned wood into streams. Wood affects every ecological and physical process in streams differently throughout seasons. However, little is known about the seasonality of wood functions in fire-prone biomes and how it combines with wood burning level to guide future postfire restoration efforts.

Through an extensive three-year seasonal tracking of stream wood following forest fires in central Portugal, we examined for the first time the influence of burning level, season, and a large suite of driving factors on the likelihood of each of four functions with primary ecological consequences — retention of organic matter, serving as substrate for aquatic biota, being key pieces forming wood jams, and deflecting flow including pool habitat formation.

Our results strongly support that one of the main ecological functions of wood in rivers, i.e. to provide substrate for biological organisms — namely for vegetation, periphyton, biofilms, and ovipositions — can be negatively affected in heavily burned wood.

Except for jam formation, the probability of each stream wood function changed markedly with season and the probability of non-function was nearly twice as high in the Euro-Mediterranean dry as in the wet season.

More anchored and decayed wood increased the probability of all functions, whereas the effect of submergence depended on the function. Challenging the “size paradigm” assuming larger-sized pieces to provide more function, our data suggest the effect of size to be function-specific.

Synthesis and applications. We show how postfire restoration success can be maximized by selecting the most appropriate wood, taking advantage of attribute-function relationships and choosing the right timing for operations. We urge managers to refrain from removing wood or to selectively remove the most heavily carbonized only, allowing the persistence of great potential to provide substrate for stream biota. The non-attraction of heavily burned wood as substrate can be compensated for by other wood with attributes enhancing this function, such as wood deeper within the bankfull area, and with large diameters. These results help to inform successful management, as is increasingly asked from restoration ecology.
Molecular-replacement phasing using predicted protein structures from AWSEM-Suite
Authors: Jin Shikai , Miller Mitchell D. , Chen Mingchen , Schafer Nicholas P. , Lin Xingcheng , Chen Xun , Phillips George N. , Wolynes Peter G.
Published: October 2020

The phase problem in X-ray crystallography arises from the fact that only the intensities, and not the phases, of the diffracting electromagnetic waves are measured directly. Molecular replacement can often estimate the relative phases of reflections starting with those derived from a template structure, which is usually a previously solved structure of a similar protein. The key factor in the success of molecular replacement is finding a good template structure. When no good solved template exists, predicted structures based partially on templates can sometimes be used to generate models for molecular replacement, thereby extending the lower bound of structural and sequence similarity required for successful structure determination. Here, the effectiveness is examined of structures predicted by a state-of-the-art prediction algorithm, the Associative memory, Water-mediated, Structure and Energy Model Suite (AWSEM-Suite), which has been shown to perform well in predicting protein structures in CASP13 when there is no significant sequence similarity to a solved protein or only very low sequence similarity to known templates. The performance of AWSEM-Suite structures in molecular replacement is discussed and the results show that AWSEM-Suite performs well in providing useful phase information, often performing better than I-TASSER-MR and the previous algorithm AWSEM-Template.
The political implications of Beethoven's music in China, 1949–1959: an examination of the publication and performance of Beethoven's music
Authors: Tsang Edmond
Published: October 2020

Purpose

One of the standard practices of Communist Parties around the world is to employ art, including music, as a channel to spread political ideologies. This study aims to scrutinize the reception of Beethoven's music, particularly from a political viewpoint, by the Chinese Communist Party (CCP) in the People's Republic of China (PRC) during the early years of its rule, i.e. from 1949–1959. The ambiguity of Beethoven's own political outlook may have provided an opportunity for the CCP to choose the composer and his music in support of its aims.

Design/methodology/approach

To understand why and how the CCP could exploit Beethoven and his music to support its political ideologies, a series of Chinese writings on Beethoven between 1949 and 1959 have been studied. Those literatures not only helped the composer gain reputation and popularity in the PRC, but also provided a platform for the CCP to manipulate such candidate and his music. Finally, the reception of the performances of the Ninth Symphony in 1959 in the PRC is singled out for close examination.

Findings

During the first ten years of the establishment of the PRC, the quantity and quality of the articles on Beethoven expanded considerably. These writings continued to reflect the reception of Beethoven and his music with the addition of political nuances that could be interpreted in the CCP's favour.

Originality/value

This paper seeks to examine the PRC's artistic policies, with a particular emphasis on the reception of Beethoven and western classical music.
Barriers to implementing waste-to-energy projects in Sri Lanka: a PESTEL analysis
Authors: Kumarasiri Binashi , Dissanayake Piumi
Published: October 2020

Purpose

It is no surprise that garbage is not garbage for some. It is money. This is why garbage has been overestimated to a point that money allocated for waste-to-energy (WtE) projects feed individual pockets. Many countries have already adapted WtE as a successful solution for both energy and waste crisis. Although in Sri Lanka six WtE projects were promised, the government abruptly decided that it would not have any more projects other than the two plants that were under construction. The purpose of this paper is to analyse barriers to the implementation of WtE projects in Sri Lanka.

Design/methodology/approach

An exploratory case study was selected as the research strategy to achieve the research aim. In total, two WtE megaprojects, which have been initiated implementation in Sri Lanka, were used as cases. A total of 12 semi-structured interviews with four personnel from each case and four government officials were used as the data collection technique. Data analysis was carried out using code-based content analysis. The barriers were extracted through analysis of case findings using an abductive analysis. The strategies to mitigate identified barriers were formulated based on attributes highlighted through case study findings and further validated through the opinions of three experts.

Findings

Barriers were analysed using the PESTEL framework to get ample insight into barriers that impact on the implementation of WtE projects in Sri Lanka. Less support from the government due to their less awareness on WtE, high investment and operational cost, lack of expert knowledge on WtE technologies in Sri Lanka, absence of a proper regulatory framework for implementation WtE technologies, lengthy process and delay in getting approvals from government process, poor attitudes of public and their protests due to the less awareness on WtE are the foremost barriers identified in this study. Further, strategies were proposed based on the empirical research findings to overcome barriers to facilitate the successful implementation of WtE projects in Sri Lanka.

Research limitations/implications

So far only two WtE megaprojects have been initiated the implementation in Sri Lanka. Therefore, the scope of the study was limited only to those projects. Moreover, the type of waste considered in this study is municipal solid waste (MSW), which has become a bigger problem in Sri Lanka.

Originality/value

The current study unveils an analysis of barriers for implementation of WtE projects in Sri Lanka, including strategies for mitigating identified barriers. The findings would enable relevant stakeholders, i.e. policymakers, industry practitioners, investors, government bodies and researchers to make informed decisions on implementation of WtE projects and thereby promote successful implementation of WtE projects in Sri Lanka.
Data-driven innovation processes within federated networks
Authors: Rizk Aya , Ståhlbröst Anna , Elragal Ahmed
Published: October 2020

Purpose

Within digital innovation, there are two significant consequences of the pervasiveness of digital technology: (1) the increasing connectivity is enabling a wider reach and scope of innovation structures, such as innovation networks and (2) the unprecedented availability of digital data is creating new opportunities for innovation. Accordingly, there is a growing domain for studying data-driven innovation (DDI), especially in contemporary contexts of innovation networks. The purpose of this study is to explore how DDI processes take form in a specific type of innovation networks, namely federated networks.

Design/methodology/approach

A multiple case study design is applied in this paper. We draw our analysis from data collected over six months from four cases of DDI. The within-analysis is aimed at constructing the DDI process instance in each case, while the crosscase analysis focuses on pattern matching and cross-case synthesis of common and unique characteristics in the constructed processes.

Findings

Evidence from the crosscase analysis suggests that the widely accepted four-phase digital innovation process (including discovery, development, diffusion and post-diffusion) does not account for the explorative nature of data analytics and DDI. We propose an extended process comprising an explicit exploration phase before development, where refinement of the innovation concept and exploring social relationships are essential. Our analysis also suggests two modes of DDI: (1) asynchronous, i.e. data acquired before development and (2) synchronous, i.e. data acquired after (or during) development. We discuss the implications of these modes on the DDI process and the participants in the innovation network.

Originality/value

The paper proposes an extended version of the digital innovation process that is more specifically suited for DDI. We also provide an early explanation to the variation in DDI process complexities by highlighting the different modes of DDI processes. To the best of our knowledge, this is the first empirical investigation of DDI following the process from early stages of discovery till postdiffusion.
Industry instructors' perspective on internship implementation strategy
Authors: Lan Chun-Chi
Published: October 2020

Purpose

The perspectives of industry instructors from a case enterprise were adopted to analyze various contexts of internship implementation and to examine feasible strategies for incorporating internships in the human resource development process.

Design/methodology/approach

A Taiwanese enterprise stationed in China was selected for case study. This study focused on the 2019 summer internship program. Interviews were conducted with 23 industry instructors.

Findings

(1) Units should effectively employ interns by guiding them to learn by doing tasks. (2) Provide training and assign personal industry instructors to guide interns in learning by doing, thereby establishing workplace relationships in advance. (3) High-level leaders and senior managers must pay close attention to internship results and inspire industry instructors and interns to perform internship tasks. (4) Managers of internship units must participate in interviews to select potential employees that satisfy unit requirements. (5) Opportunities for university teachers to interact with enterprises and recommend interested students who learn knowledge, skills, abilities and other characteristics (KSAOs) that fulfill enterprise requirements should be increased.

Practical implications

Enterprises must systematically plan internship tasks, recruitment and selection, as well as practices and reports if they wish to employ interns as potential human resource.

Originality/value

This study used the practical perspectives of industry instructors to establish the contexts and strategies of intern training for human resource development. The results of this study are expected to provide a reference for enterprises in planning internship workplaces and increase their willingness to employ interns.
Shaping the event portfolio management field: premises and integration
Authors: Ziakas Vassilios , Getz Donald
Published: October 2020

Purpose

This paper aims to examine how various academic disciplines shape the field of event portfolio management. Given the complex nature of portfolios comprising different genres that are studied separately from their respective disciplinary realms, the academic event portfolio landscape remains fragmented. This is against the nature of portfolios, which requires inter-disciplinarity and novel integration of genres, stakeholders and perspectives.

Design/methodology/approach

Based on a scoping literature review, this conceptual paper sets up a common ground for the academic study and industrial development of event portfolio management.

Findings

A comprehensive view of event portfolio literature across disciplines reveals its hypostasis as a compound transdisciplinary field. The authors suggest a set of foundational premises whereby they identify 22 principal thematic areas that comprise this emerging field.

Practical implications

The establishment of event portfolio management as a distinct field will help in the osmosis and diffusion of new ideas, models and best practices to run and leverage portfolios. The portfolio perspective highlights the need for cohesive learning to design comprehensive systems of events, implement joint strategies, solidify social networks, coordinate multiple stakeholders and develop methods of holistic evaluation.

Originality/value

By examining comprehensively event portfolio management as a transdisciplinary field, the authors have been able to identify principal research directions and priorities. This comprehensive analysis provides a synergistic ground, which at this embryonic stage of development, can be used to set out joint trajectories and reciprocal foci across the whole span of scholarship studying planned series of events.
Safeguarding adults practice and remote working in the COVID-19 era: challenges and opportunities
Authors: Anka Ann , Thacker Helen , Penhale Bridget
Published: October 2020

Purpose

This exploratory paper aims to examine the literature on the impact of COVID-19 on safeguarding adults practice.

Design/methodology/approach

A literature search was carried out in recently published articles to locate literature relating to COVID-19 and safeguarding adults in the UK and internationally. This included policy guidance and law, to describe the existing knowledge base, gaps in practice and areas that may require further research.

Findings

The findings suggest that measures to curb the spread of the COVID-19 pandemic gave rise to remote working and virtual safeguarding practice. The findings highlight the need for empirical research into the impact of virtual safeguarding adults assessments and effective ways to support the needs and outcomes of those who may be at risk of or experiencing abuse and neglect while shielding, socially isolating or when working in an environment where social distancing is required.

Research limitations/implications

The paper is based on a review and analysis of published documents and not on other types of research.

Originality/value

Little is known about effective safeguarding adults practice in the era of shielding, self-isolation, social distancing and remote working. The paper adds to the body of knowledge in the field.
Evaluation of dyeing properties of natural dyes extracted from the heartwood of Prosopis juliflora on cotton fabric
Authors: Odero Mark Peter , Kiprop Ambrose Kipchumba , K'Owino Isaac Odhiambo , Arimi Milton , Manyim Scolastica
Published: October 2020

Purpose

Considered as one of the most unwanted species by the International Union for Conservation of Nature, the Prosopis juliflora plant is a noxious and invasive weed. Recent studies suggest that the heartwood of the plant has an unusually high amounts of flavonoids with potential medicinal properties and dyeing potentials. In this work, acetonic extracts were successfully valorized into a natural dye.

Design/methodology/approach

After extraction and optimization of dyeing conditions, the fabric was treated by using pre-mordanting, simultaneously mordanting and post mordanting techniques. The dyed samples were then evaluated by using standard methods ISO 105-C06, ISO 105-A02, ISO 105-X12 for wash, light and rub fastness, respectively.

Findings

Dye fastness ranged from good to very good with mordants improving both wash and rub fastness. Optimum pH for dyeing was found to be at 7.2 at temperatures of 60°C and a dyeing time of 80 min. Application of mordant in dyeing white fabric showed improved dyeing properties in post mordanting than both pre-mordanting and simultaneous mordanting.

Originality/value

To best of the authors’ knowledge, this paper details for the first time how a noxious weed can be transformed into a natural dye, with potential applications to the textile industry.
The importance of wetland margin microhabitat mosaics; the case of shorebirds and thermoregulation
Authors: Ryeland Julia , Weston Michael A. , Symonds Matthew R. E.
Published: October 2020

Wetlands, and the species that rely upon them, are under significant threat world‐wide, with wetlands often being completely removed or drastically altered. Successful wetland management requires an understanding of the interactions between wetland species and the microhabitats they use. The use of microhabitats for thermoregulation in wetland species is poorly studied, though anthropogenic influence on wetlands can reduce the diversity of microhabitats and thus the thermoregulatory options for animals. At high ambient temperatures birds may use the water‐logged wetland margins to help with thermoregulation, and are often observed roosting in the sitting position within this microhabitat. However, whether sitting on the wet substrate helps in thermoregulation is unknown.

In this study, we tested whether birds selectively use microhabitats across temperatures by conducting field observations of nine species of shorebirds. We use comparative analysis to determine whether birds roost more on wet substrate in the sitting posture, that is, ‘wet‐sitting’, at high ambient temperatures.

We found substrate type across the wetland margins to be important in shorebird thermoregulation, with the time spent sitting being significantly mediated by the substrate on which the bird roosted. Individuals tended to sit on bare, wet ground much more under high ambient temperatures compared with low ambient temperatures. Vegetation on the other hand was used similarly across temperatures, and likely does not provide the same thermoregulatory benefits.

By roosting on wet substrate at high ambient temperatures, birds may increase the potential for heat dissipation across the uninsulated legs, as water‐logged wetland margins are known to remain cooler than the ambient temperature or vegetated microhabitats under hot climatic conditions.

Synthesis and applications. Wetland creation and management requires an understanding of the functional significance of such microhabitats, not only for foraging and breeding, but also for roosting. We demonstrate that managing wetland margins is likely important in minimising heat stress in birds, with our findings emphasising the importance of maintaining open spaces in habitat mosaics for birds to use for thermoregulation. The ability of wetland species to manage heat stress is becoming exceedingly important as they are threatened by both decreased wetland availability and increasing ambient temperatures under climate change.
From macro to micro: a combined bioluminescence‐fluorescence approach to monitor bacterial localization
Authors: Soldan Riccardo , Sanguankiattichai Nattapong , Bach‐Pages Marcel , Bervoets Indra , Huang Wei E. , Preston Gail M.
Published: October 2020

Bacterial bioluminescence is widely used to study the spatiotemporal dynamics of bacterial populations and gene expression in vivo at a population level but cannot easily be used to study bacterial activity at the level of individual cells. In this study, we describe the development of a new library of mini‐Tn7‐lux and lux::eyfp reporter constructs that provide a wide range of lux expression levels, and which combine the advantages of both bacterial bioluminescence and fluorescent proteins to bridge the gap between macro‐ and micro‐scale imaging techniques. We demonstrate that a dual bioluminescence‐fluorescence approach using the lux operon and eYFP can be used to monitor bacterial movement in plants both macro‐ and microscopically and demonstrate that Pseudomonas syringae pv phaseolicola can colonize the leaf vascular system and systemically infect leaves of common bean (Phaseolus vulgaris). We also show that bacterial bioluminescence can be used to study the impact of plant immune responses on bacterial multiplication, viability and spread within plant tissues. The constructs and approach described in this study can be used to study the spatiotemporal dynamics of bacterial colonization and to link population dynamics and cellular interactions in a wide range of biological contexts.
FTA, Exchange rate pass‐through and export price behavior – Lessons from the Australian dairy sector
Authors: Permani Risti
Published: October 2020

The growing number of bilateral and regional free trade agreements (FTAs) alongside exchange rate volatility has raised a question on whether these affect exporters’ pricing behaviors, hence competitiveness. This study contributes to this topic by examining Australian dairy export price behavior across eight major markets taking into account the extent of pass‐through of exchange rate and tariff as well as FTAs between Australia and its trading partners. Commodity‐level dairy trade data from 1996 to 2016 and the feasible generalized least squares methods are employed. The study finds incomplete pass‐through at the industry level. The dairy export prices decrease by 1.7% if Australian dollar depreciates by 10%, while 10% tariff reduction is associated with 0.7% export price cut. Results at the commodity level show different pricing behaviors across destination and commodity markets. Overall, apart from the tariff effects, there is minimal evidence of the impacts of FTAs on dairy export prices.
A test of the Bulut et al. (2016) landmark‐free method of quantifying sex differences in frontal bone roundness in a contemporary Czech sample
Authors: Čechová Markéta , Dupej Ján , Brůžek Jaroslav , Bejdová Šárka , Velemínská Jana
Published: October 2020

The skull, along with the pelvic bone, serves an important source of clues as to the sex of human skeletal remains. The frontal bone is one of the most significant sexually dimorphic structures employed in anthropological research, especially when studied by methods of virtual anthropology. For this reason, many new methods have been developed, but their utility for other populations remains to be verified. In the present study, we tested one such approach—the landmark‐free method of Bulut et al. (2016) for quantifying sexually dimorphic differences in the shape of the frontal bone, developed using a sample of the Turkish population. Our study builds upon this methodology and tests its utility for the Czech population. We evaluated the shape of the male and female frontal bone using 3D morphometrics, comparing virtual models of frontal bones and corresponding software‐generated spheres. To do so, we calculated the relative size of the frontal bone area deviating from the fitted sphere by less than 1 mm and used these data to estimate the sex of individuals. Using our sample of the Czech population, the method estimated the sex correctly in 72.8% of individuals. This success rate is about 5% lower than that achieved with the Turkish sample. This method is therefore not very suitable for estimating the sex of Czech individuals, especially considering the significantly greater success rates of other approaches.
Gelation and microstructural properties of a millet‐based yogurt‐like product using polymerized whey protein and xanthan gum as thickening agents
Authors: Song Xiao , Sun Xiaomeng , Ban Qingfeng , Cheng Jianjun , Zhang Siyu , Guo Mingruo
Published: October 2020

Cereal‐based fermented products are becoming popular in the world. A millet‐based yogurt‐like product (MYP) using polymerized whey protein (PWP) and xanthan gum (XG) as thickeners was developed. The present study aimed to investigate the effects of PWP (0.3 to 0.5%, w/v) and XG (0 to 0.2%, w/v) on the gelation properties and microstructure of MYP. All samples were analyzed for rheological properties, textural properties, microstructure, and pH value during fermentation. The MYP Ⅲ (0.4% PWP and 0.1% XG) registered the highest elastic modulus (G′) throughout the fermentation and cooling steps (P < 0.05), but MYP Ⅳ (0.35% PWP and 0.15% XG) had the highest apparent viscosity compared with the other samples. No significant differences in the pH values among the samples were observed during the fermentation process (P > 0.05). The hardness value of MYP Ⅳ reached a maximum after 4 hr and then stabilized during fermentation. Scanning electron microscopy showed a compact and uniform network for the MYP with PWP and XG. MYP Ⅳ had the best texture properties (hardness, springiness, and gumminess). Overall, PWP (0.35%, w/v) and XG (0.15%, w/v) were the best combination for MYP as a thickening system.

Practical Application

Cereal‐based fermented products have attracted much attention in the food industry. However, due to absence of a natural protein network, it is hard to produce a set‐type millet‐based yogurt with a firm texture under the studied conditions without adding any thickening agents. In this study, PWP (0.35%, w/v) and XG (0.15%, w/v) can be used for fermentation of millet‐based yogurt‐like products. The new cereal‐based fermented product would be a promising food in the market.
Does the Unconscious Influence Our Ethnography? Psychoanalysis during Fieldwork in Argentina
Authors: Robben Antonius C. G. M.
Published: October 2020

Ethnographic fieldwork is an emotional research practice because of its intersubjective nature and empathic embrace of the actor’s perspective. This intersubjectivity also involves the fieldworker’s unconscious, which influences ethnographic encounters and anthropological interpretations. Two years of psychoanalysis in Argentina revealed the influence of the unconscious on my fieldwork about political violence and trauma through dream analyses and the analyst’s interventions. This understanding improved the rapport with research participants and opened an alternative road to reflexivity.