bluuebunny/crossref_metadata_2025 huggingface dataset:
Innovación Social como herramienta en la transformación de una sociedad inclusiva. Accesibilidad e Innovación Social
Authors: Sampedro Palacios Cristina Belén , Pérez Villar Juana
Published: November 2019

En la actualidad hablar de Accesibilidad tiene mucho que ver con hablar de inclusión social, puesto que conseguir que una sociedad sea accesible es hacerla inclusiva.

La Accesibilidad ha evolucionado a lo largo del tiempo, adaptándose a los cambios sociales que se han ido produciendo. Tradicionalmente, se ha visto asociada a la eliminación de barreras arquitectónicas, pero en la actualidad, hablar de Accesibilidad Universal va más allá de la llamada Accesibilidad física o urbanística. Contemplando una amplia variedad de materias que aglutinan muchos tipos de Accesibilidad concernientes a diversas esferas de la vida de una persona.

Desde este estudio se trata de revisar la evolución de la Accesibilidad desde sus orígenes hasta la actualidad, tratando de conocer sus características, para después poder vincularla con la Innovación Social como aliada, al objeto de contribuir en el logro de una sociedad inclusiva y accesible para todas las personas, donde la diversidad que caracteriza al ser humano se perciba como un valor añadido. Todo ello con un enfoque desde el Trabajo Social como promotor de bienestar social y calidad de vida de la ciudadanía.
Las condiciones de bienestar laboral en una empresa del sector hotelero. Estudio de caso en Medellín, Colombia
Authors: Jiménez González Gloria María , Rivera Ladino Ana María , Gaibao Pérez María Carolina
Published: November 2019

Las condiciones de bienestar laboral de los trabajadores de una empresa del sector hotelero de la ciudad de Medellín, se abordan con el fin de conocer sus características de vida las que, de alguna manera, pueden afectar su productividad, poner en riesgo sus condiciones psicosociales y el logro de la estrategia del negocio. Desde la profesión del Trabajo Social en unión con el área de Gestión Humana se profundiza la calidad de vida y la percepción que los trabajadores tienen de su empresa a través de una investigación con énfasis cuantitativo y estudio de caso como estrategia. El instrumento utilizado fue la encuesta semiestructurada. El estudio indica que en Medellín no se han adelantado investigaciones relacionadas con las condiciones de vida y el Bienestar laboral de los trabajadores de una empresa del sector hotelero.

A pesar de los resultados, de los cuales se resalta que la mayoría ganan entre uno o dos salarios mínimos, los trabajadores manifiestan satisfacción y sentido de pertenencia hacía la empresa, donde el salario no es su mayor motivación, al contrario, el buen trato, los beneficios, la estabilidad, el apoyo en momento de crisis, se convierten en los mayores atractivos para formar parte de esta organización.
El abuso económico y la violencia de género en las relaciones de pareja en el contexto puertorriqueño
Authors: Silva Martínez Elithet , Vázquez Pagán Jenice M.
Published: November 2019

Los estudios sobre la violencia de género en las relaciones de pareja se han trabajado con dimensiones del abuso físico, emocional y sexual. En este trabajo se propone añadir el abuso económico como una dimensión adicional. El abuso económico presenta unas características específicas que afectan de manera significativa la vida de las sobrevivientes y sus hijos e hijas. Es importante definir las mismas y proponer modos de acción desde la práctica y la política social. Para lograr este objetivo, es necesario desarrollar una agenda de investigación que contribuya al desarrollo de saberes en esta área. De igual forma, es necesario que los estados desarrollen e implanten de manera efectiva políticas sociales que atiendan el abuso económico como una dimensión diferente de la violencia de género en las relaciones de pareja y al reconocerlo, lograr el empoderamiento económico de las mujeres sobrevivientes de violencia de género y sus hijos e hijas. En este trabajo presentaremos la experiencia de Puerto Rico y ofrecemos algunas recomendaciones sobre este particular.
La perspectiva de género como apuesta política en la intervención social de Trabajo Social
Authors: Chacon Gironza Laura Sofía
Published: November 2019

Este artículo analiza los desafíos y dificultades que afrontan los/as profesionales de Trabajo Social en su proceso de intervención (principalmente los vinculados al sector salud) y propone elementos teórico-prácticos que permitan enfrentar la dinámica neoliberal, a través de una mirada crítica sobre la realidad social.

El estudio parte de la perspectiva de género como medio para identificar y analizar los mal llamados “problemas sociales” de la población en general, haciendo un mayor énfasis en el caso de las mujeres de la ciudad de Cali que se encuentran en situaciones de discriminación, opresión y violencia. Se analiza el ámbito de la intervención social en la lógica neoliberal, con mayor énfasis en el sector salud. También se aborda la formación académica en Trabajo Social, sus avances y dificultades, en la Universidad del Valle. Por último, se demuestra la importancia de la perspectiva de género en el ejercicio de la profesión, concluyendo que son herramientas teórico-prácticas indispensables para comprender y analizar el contexto social con el fin de avanzar en análisis críticos.
La participación comunitaria como vía para el empoderamiento de encargadas del programa Comedores Comunitarios en Culiacán, México
Authors: Verdugo Araujo Luz Mercedes , Tereso Ramírez Leonor , Carrillo Montoya Teresita del niño Jesús
Published: November 2019

El artículo analiza la experiencia de mujeres participantes en un programa social que tiene como finalidad abatir el hambre. Ellas se han convertido en mediadoras de la localidad y por tanto en el enlace entre el aparato institucional y los beneficiarios. Asimismo, se han posicionado como actoras protagónicas en la comunidad y si bien han logrado alcanzar cierto grado de empoderamiento mediante la participación comunitaria, en el terreno político enfrentan circunstancias que limitan su pleno desarrollo. El objetivo de este trabajo es la reflexión sobre la construcción del proceso de empoderamiento que se genera en la cotidianidad de las mujeres líderes del programa Comedores Comunitarios, identificando sus estrategias políticas, sociales y culturales producto de su acción social. La ruta metodológica está basada en un análisis hermenéutico-interpretativo que se desprende de los discursos de 27 mujeres que operan el programa Comedores Comunitarios en el municipio de Culiacán, Estado de Sinaloa, México. Se concluye que el empoderamiento no es un proceso que pueda darse a otras personas, es más bien, un proceso individual, de auto confrontación, de auto cuestionamiento la situación en que se encuentran cada mujer y cada hombre dentro de una comunidad.
Artista invitado Antonio Patiño-Santa
Authors: Patiño Santa Antonio
Published: November 2019

Artista invitado Antonio Patiño-Santa
Presentación
Authors: Rincón Salazar María Teresa
Published: November 2019

Con el presente número conmemoramos los 25 años de PROSPECTIVA, publicación de la Escuela de Trabajo Social y Desarrollo Humano de la Universidad del Valle, Colombia. En la página editorial del Nº1 del año 1994 se afirma: “Publicar una revista, y sobre todo mantenerla, significa un importante esfuerzo editorial que esta Unidad Académica debe realizar hacia el futuro, con el fin de poder recoger de manera continua y sistemática lo mejor de la producción intelectual de profesores, estudiantes de postgrado, profesionales en Trabajo Social y demás profesionales de las Ciencias Sociales a nivel Regional, Nacional e Internacional
Electrohydraulic Lithotripsy in the Treatment of the Mirizzi Syndrome. A Clinical Case
Authors: Gabriel Sergei A. , Guchetl Aleksandr Y. , Durleshter Vladimir M. , Dynko Viktor Yu. , Tlekhuray Ruslan M. , Bespechnyi Mikhail V. , Mamishev Adam K.
Published: November 2019

Aim. To present an interesting case of treating cholelithiasis in the setting of the Mirizzi syndrome.

Materials and methods. This paper presents a clinical case of patient A. (62 years old) who was admitted to hospital with the following diagnosis: cholelithiasis, cholecysto-choledocholithiasis, obstructive jaundice. Drawing on the medical history and complaints of the patient, as well as on the results of physical, laboratory, instrumental and preliminary examination, the patient was diagnosed with choledocholithiasis in the setting of the Mirizzi syndrome. Endoscopic retrograde cholangiopancreatography (ERCP) was prescribed. The ERCP was performed in four stages. The first stage included a typical endoscopic papillotomy, a retrograde cholangiopancreatography, as well as an attempt at endoscopic mechanical lithoextraction; however, the calculus could not be removed. During the second stage, the calculus was visually localized, and its size was determined. The third stage consisted in performing electrohydraulic lithotripsy (EHL) and mechanical lithoextraction of calculus fragments. The final, fourth stage involved follow-up direct cholangioscopy, which revealed that the common bile duct was patent and there were no calculi.

Results. EHL constitutes a high-tech method of crushing calculi, which provides an opportunity to carry out minimally invasive treatment in patients with complicated cases of choledocholithiasis, when standard methods of mechanical lithoextraction are not effective.
Nikolay N. Petrov: Ethos of a Scientist and a Doctor
Authors: Redko Andrey N. , Kovelina Tatyana A. , Nikulina Ekaterina L. , Veselova Darya V. , Kuzmenko Mariya S.
Published: November 2019

Aim. In this work, the authors set out to perform a historical analysis of Nikolay Petrov’s life journey and scientific work, as well as to demonstrate the importance of the Kuban period in his formation as an individual, a scientist and as a founder of domestic medical deontology.

Materials and methods. In this study, the authors used archival documents; works of Nikolay Petrov; as well as the following methods: historical-descriptive, comparative-historical, problem-chronological, biographical along with the method of monographic description.

Results. The life and professional journey of Nikolay Petrov can be divided into several periods, each of them playing an important role in his formation as an individual and as a scientist. The fi rst period (‘St Petersburg period’) covers his brilliant upbringing, education at the Military Medical Academy in Saint Petersburg, work as a medical resident at the Surgery Department of the Academy, as well as the publication of his first scientific works and the defence of the doctoral thesis in medicine. During the second period (‘abroad period’), Nikolay Petrov completed advanced training at the Pasteur Institute and worked at the clinics of Switzerland, Austria and Germany. The third period (‘teaching period’) covers the time when Nikolay Petrov was simultaneously working as a surgeon and a teacher at the Military Medical Academy; his fundamental works on surgery and oncology were published. The forth ‘military period’ coincided with the years of the First World War when Nikolay Petrov worked as a surgeon at the hospitals of the Russian Red Cross Society while continuing his research. The fifth period (‘Kuban period’) coincided with the years of revolutionary upheavals, civil war and moving to Kuban. In 1917–1922 Nikolay Petrov had to choose between emigration and his motherland. He stayed true to his profession and his homeland. Nikolay Petrov devoted himself to serving the ‘new’ country, actively participated in the organisation of the Kuban Medical University and wrote a number of works on surgery, including the first work on medical deontology in the country. The sixth period is called ‘return to St Petersburg’ where in 1925 Nikolay Petrov organised the Oncology Department at the Mechnikov hospital, which under his guidance became the first research institute for oncology in our country. This period was marked by the recognition of his talent as a doctor and a scientist by the public and government.

Conclusion. Nikolay Petrov‘s ethos as a scientist and a doctor was formed under the influence of his challenging life journey, with the Kuban period being a turning point in his life.
Morphological Changes in the Dental Pulp of Experimental Animals in the Treatment of Acute Partial Pulpitis using Modern Materials
Authors: Ivashchenko Victoria А. , Adamchik Anatoly А. , Аrutyunov Armenak V. , Risovanny Sergey I. , Sidorenko Alexander N. , Tsymbalov Oleg V.
Published: November 2019

Aim.To study the morphological changes in the tooth pulp of experimental animals when modelling acute partial pulpitis using calcium silicate modified with light-cured resin and calcium hydroxide.

Materials and methods.An experimental model of acute partial pulpitis was applied including the formation of a cavity on the lingual surface of the tooth, which corresponded to advanced caries in terms of depth, followed by a slight perforation up to the tooth pulp with a sharp probe. This model of acute partial pulpitis was reproduced for 32 teeth in four sexually mature rams. The teeth were extracted together with the surrounding sockets 15, 30 and 90 days after the modelling of pulpitis, followed by their fi xation in 10% solution of neutral formalin. Decalcification was performed in 25% solution of Trilon B. The material was poured into celloidin; histological sections were stained with hematoxylin and eosin according to Masson’s trichrome procedure.

Results.The histological examination of pulp from the main group (calcium silicate modified with light-cured resin) revealed the formation of a biological barrier from secondary dentin in the area of the cavity and perforation up to the pulp chamber on the 90th day after the experiment started. The tooth pulp revealed no signs of an inflammatory process. On the 90th day after the experiment started, no pronounced morphological changes in the main substance and dentinal tubules in the area of the cavity walls were noted in the coronal pulp of experimental animals from the comparison group (calcium hydroxide). A focal chronic inflammatory process was noted in the tooth pulp.

Conclusion.It was established that the use of calcium silicate modified with light-cured resin in the experimentally created model of acute partial pulpitis was accompanied by the formation of a biological barrier and a well-developed zone of reparative dentin in the area of the cavity and perforation up to the pulp chamber, as compared to the group where calcium hydroxide was used. Thus, the study results confirmed the efficay of using calcium silicate modified with light-cured resin within the biological method for treating acute partial pulpitis, which shortens the functional recovery of tooth pulp.
The Level of Oxidative Stress Markers in Generalised Periodontitis in the Setting of Bronchiectasis
Authors: Kibkalo Anatoly P. , Sarkisov Artem K. , Polunina Ekaterina A. , Sarkisov Karen A.
Published: November 2019

Aim. To analyse the level of oxidative stress markers and the value of dental indices characterising the state of periodontal tissue in patients with generalised periodontitis (GP) both without somatic pathology and with bronchiectasis.

Materials and methods. Over the period from 2015 to 2017, a total of 90 GP patients were examined, including 40 patients without somatic pathology and 50 patients with bronchiectasis. The control group consisted of somatically healthy individuals with intact periodontium (n=40). The following indices were calculated for all examined individuals: PMA, PI, Muhlemann and OHI-s. The level of oxidative stress markers in oral fl uid was determined: total superoxide dismutase (SOD) of all three types (Cu/Zn-SOD + Mn-SOD + Fe-SOD), products of advanced protein oxidation and malondialdehyde.

Results. The study established the intensifi cation of oxidative stress in GP patients without somatic pathology and with bronchiectasis. Patients with comorbid pathologies demonstrated a greater severity of oxidative stress. The analysis revealed a significant correlation between the values of dental indices (PMA, PI, Muhlemann, OHI-s) and the level of oxidative stress markers both in GP patients without somatic pathology and with bronchiectasis. Furthermore, this correlation is stronger in patients with comorbid pathologies.

Conclusion. The presence of comorbid pulmonary pathologies in the form of bronchiectasis in patients with generalised periodontitis can act as an aggravating factor in the development of periodontal lesions.
Comparative Efficiency of Removable Mini-Implant Retained Dentures Using Different Attachments in Edentulous Patients
Authors: Maksyukov Stanislav Yu. , Prokhodnaya Viktoria A. , Pilipenko Konstantin D. , Lapina Natalya V. , Popkov Viktor L. , Risovannaya Olga N. , Melekhov Sergey V.
Published: November 2019

Aim. To compare the efficiency of removable mini-implant retained dentures using different types of attachment.

Materials and methods. The study included 51 edentulous patients. The patients were divided into three groups according to the attachment type and abutment shape: 1) ball-and-socket attachment, ball abutment (n = 26); 2) locator attachment, equator abutment, XiVE LOCATOR system (n = 14); 3) bar attachment (n = 11). Removable dentures were made of ordinary acrylic plastic. The placement of intraosseous dental implants with their sublingual engraftment was performed according to the traditional two-stage delayed-load procedure. The efficiency of implants was evaluated using the method of M.Z. Mirgazizov and the eponymous index. The dynamics of vertical bone resorption around implants was determined using dental panoramic radiography (6 months, 1 and 2 years after the treatment). A periotest was performed 6 months after the end of the orthopaedic treatment.

Results. The one-year survival rate of implants reached 96.2% in group 1, amounting to 100% in groups 2 and 3. The two-year survival rate came to 92.3% in group 1, reaching 92.9% and 100% in groups 2 and 3, respectively. Inflammatory phenomena characteristic of peri-implantitis were noted one year after the implant placement in 7.7% (n = 2) of patients in group 1 and in 7.1% of patients in group 2, with no inflammatory phenomena being observed in group 3. Two years after the implant placement, peri-implantitis was observed in 19.2% and 21.4% of patients in groups 1 and 2, respectively, coming to 9.1% in group 3. The periotest revealed that six months after the placement, implant stability was higher in group 3 for both the lower and upper jaw (in comparison with groups 1 and 2), as evidenced by the shift in periotest values towards the negative part of the scale.

Conclusion. The study revealed that bar attachment, as well as locator attachment (equator abutments), of removable dentures supported by mini implants is more efficient as compared to the ball-and-socket attachment.
Nephrological Aspects of Balneotherapy with Uvinskaya Mineral Water in Patients with Type 2 Diаbetes
Authors: Shklyaev Aleksei E. , Kazarin Daniil D. , Gorbunov Yurii V. , Chetverikov Petr I. , Kuzyaev Mikhail V.
Published: November 2019

Aim.The present article studies the effect of balneotherapy with Uvinskaya mineral water on the microbial spectrum of urine in patients with type 2 diabetes.

Materials and methods.The study was carried out at the Endocrinology Department of the First Republican Clinical Hospital (Izhevsk). A total of 56 patients with type 2 diabetes participated in the study, which involved collecting medical history and complaint data of patients along with performing general and system-based examination, urinalysis, urine culture prior to and following the course of therapy, as well as kidney ultrasound aimed at excluding the presence of calculi. Urine cultures (morning sample) were plated onto 5% blood agar, as well as Endo’s medium for detecting bacteria from theEnterobacteriaceaefamily using the Gould method. Urine cultures were incubated for 24, 72 and 144 hours at a temperature of 37 °C. The significance of differences was determined using the t-test for independent and paired samples.

Results.Changes in urinalysis were observed in all examined patients, which included changes characteristic of urinary tract infections: a large number of bacteria per field of view; a large amount of mucus; the presence of leukocytes in urine; alkaline pH shift; as well as disorders typical of diabetes mellitus (glycosuria, proteinuria).E. colipredominated in urine cultures. Following a 30-day therapy with Uvinskaya mineral water, the number of bacteria and leukocytes, as well as the amount of mucus, detected in the urine reduced significantly, which indicates urinary tract sanation. Positive dynamics among patients who underwent balneotherapy treatment is confirmed by the Student’s t-test (p < 0.05). In addition, no urinary sanation was observed in the group of patients who did not receive balneotherapy.

Conclusion.Drawing on the study results, the authors recommend using Uvinskaya natural mineral water in the combined treatment of patients with type 2 diabetes for urinary tract rehabilitation.
An oral, selective tyrosine kinase 2 inhibitor, BMS-986165, improves quality of life in psoriasis: results from a Phase 2 study
Authors: Thaci D , Papp K , Gordon K , Morita A , Gooderham M , Foley P , Alemano E , Kisa R , Elbez Y , Ren H , Banerjee S
Published: November 2019

Abstract not available.
A multicenter, open label, Phase 1 study of the safety, tolerability, systemic exposure, pharmacodynamics, and treatment effect of calcipotriene foam, 0.005% in pediatric subjects (ages 2 to 11 years) with plaque psoriasis.
Authors: Herbert Adelaide A , Glaab Debbie , Schreiber Rhonda
Published: November 2019

Abstract not available.
Long-term Efficacy and Safety of Brodalumab in Patients With or Without History of Psoriatic Arthritis: Analysis of Two Phase 3 Psoriasis Studies
Authors: Gottlieb Alice , Menter Alan , Yamauchi Paul , Han George , Pillai Radhakrishnan , Lin Tina , Jacobson Abby
Published: November 2019

Abstract not available.
Importance of Complete Skin Clearance on Quality of Life: Analysis of Three Phase 3 Studies of Brodalumab
Authors: Armstrong April , Blauvelt Andrew , Drew Scott , Ho Roger , Jacobson Abby
Published: November 2019

Abstract not available.
Optimized Formulation for Topical Application of a Fixed Combination Halobetasol/Tazarotene Lotion Using Polymeric Emulsion Technology
Authors: Tanghetti Emil A , Gold Linda Stein , Del Rosso James Q , Weiss Stefan , Lin Tina , Angel Arturo , Pillai Radhakrishnan
Published: November 2019

Abstract not available.
Efficacy, Safety, and Tolerability of a Halobetasol 0.01%/Tazarotene 0.045% Fixed Combination in the Treatment of Moderate-to-Severe Plaque Psoriasis in a Hispanic Population: Post Hoc Analysis of Two Phase 3 Randomized Controlled Trials
Authors: Alexis Andrew F , Yamauchi Paul S , Lin Tina , Martin Gina
Published: November 2019

Abstract not available.
Efficacy, Safety, and Tolerability of a Halobetasol 0.01%/Tazarotene 0.045% Fixed Combination in the Treatment of Severe Plaque Psoriasis: Post Hoc Analysis of Two Phase 3 Randomized Controlled Trials
Authors: Lebwohl Mark G , Sugarman Jeffrey L , Gold Linda Stein , Lin Tina , Martin Gina
Published: November 2019

Abstract not available.
Long-Term Management of Moderate-to-Severe Plaque Psoriasis: Maintenance of Treatment Success Following Cessation of Fixed Combination Halobetasol Propionate 0.01% And Tazarotene 0.045% (HP/TAZ) Lotion
Authors: Gold Lina Stein , Lebwohl Mark G , Bhatia Neal , Lin Tina , Pillai Radhakrishnan
Published: November 2019

Abstract not available.
Halobetasol 0.01% Lotion in the Treatment of Moderate-to-Severe Plaque Psoriasis of the Lower Extremities
Authors: Bhatia Neal , Vlahovic Tracey C , Green Lawrence , Martin Gina , Lin Tina
Published: November 2019

Abstract not available.
Bimekizumab provides rapid and sustained improvements in scalp and nail outcomes in patients with moderate to severe plaque psoriasis: 60 week results from a randomized, double blinded, Phase 2b extension study
Authors: Blauvelt Andrew , Papp Kim A , Merola Joseph F , Gottlieb Alice B , Cross Nancy , Madden Cindy , Peterson Luke , Cioffi Christopher , Griffiths Christopher EM
Published: November 2019

Abstract not available.
Long-Term Efficacy of Certolizumab Pegol Dosed at 400 mg Every Two Weeks in Patients with Plaque Psoriasis: Pooled 128-Week Data from Two Phase 3 Trials (CIMPASI-1 and CIMPASI-2)
Authors: Gordon K , Warren R.B. , Gottlieb A.B. , Blauvelt A , Thaci D , Leonardi C , Poulin Y , Boehnlein M , Kavanagh S , Arendt C , Reich K
Published: November 2019

Abstract not available.
Efficacy of Certolizumab Pegol for Psoriasis of the Head and Neck in Two Phase 3 Clinical Trials: CIMPASI-1 and CIMPASI-2
Authors: Van de Kerkhof P , Pinter A , Boehnlein M , Kavanagh S , Crowley J.J.
Published: November 2019

Abstract not available.
Lebrikizumab, a High-Affinity IL-13 Inhibitor, Improves Clinical Manifestations in Moderate-to-Severe Atopic Dermatitis: Primary Results From a Randomized, Double-Blinded, Placebo-Controlled, Dose-Ranging, Phase 2b Study
Authors: Guttman-Yassky E , Blauvelt A , Eichenfield L.F. , Paller A , Armstrong A , Drew J , Gopalan R , Simpson E
Published: November 2019

Abstract not available.
Atopic dermatitis disease biomarkers strongly correlate with IL-13 levels, are regulated by IL-13, and are modulated by tralokinumab in vitro
Authors: Weidinger Stephan , Tollenaere Maxim A.X. , Drerup Katharina , Litman Thomas , Norsgaard Hanne
Published: November 2019

Abstract not available.
A Comparison of Efficacy among Therapeutic Moisturizing Creams
Authors: Arrowitz CE , Jiang LI , Hino PD , Babcock MJ , Weber TM
Published: November 2019

Abstract not available.
A 14 Day, Single Blind, Controlled Study to Assess the Qualitative Improvement in Skin Moisturization and Desquamation of 15% Lactic Acid Moisturizer with Ceramides (LAMC) Treatment in Healthy Female Subjects
Authors: Draelos Zoe Diane , Hall Steven B , Munsick Carey
Published: November 2019

Abstract not available.
Safety of Large Field (>20cm2) Photodynamic Therapy Using 10% Aminolevulinic Acid Hydrochloride Nanoemulsion Gel Comparing Blue to Red Light Illumination
Authors: Moore Angela Yen , Moore Stephen
Published: November 2019

Abstract not available.
Novel Tretinoin 0.05% Lotion for the Once-Daily Treatment of Moderate-to-Severe Acne Vulgaris in an Asian Population
Authors: Han George , Armstrong April W , Desai Seemal R , Guenin Eric
Published: November 2019

Abstract not available.
Multidisciplinary Expert-Driven Consensus on the Evolving Treatment of Patients with Advanced Cutaneous Squamous Cell Carcinoma
Authors: Migden Michael R , Schlesinger Todd E , Schmults Chrysalyne D , Dinehart Scott M , Ferris Robert L , Freeman Morganna , Guild Valerie , Koyfman Shlomo , Pavlick Anna C , Wolf Gregory T , Rabinowits Guilherme , Swanson Neil
Published: November 2019

Abstract not available.
Findings from a large US registry study to assess the real-world utility of a non-invasive gene expression test designed to rule out primary cutaneous melanoma
Authors: Brouha Brook , Ferris Laura K , Skelsey Maral K , Peck Gary , Yao Zuxu , Jansen Burkhard
Published: November 2019

Abstract not available.
Association Between Baseline Disease Characteristics and Relapse-Free Survival in Patients With BRAF V600–Mutant Resected Stage III Melanoma Treated With Adjuvant Dabrafenib + Trametinib or Placebo
Authors: Schadendorf Dirk , Dummer Reinhard , Hauschild Axel , Santinami Mario , Atkinson Victoria , Mandala Mario , Chiarion-Sileni Vanna , Larkin James , Nyakas Marta , Dutriaux Caroline , Haydon Andrew , Mortier Laurent , Robert Caroline , Schachter Jacob , Ortmann Christine-Elke , De Jong Egbert , Gasal Edward , Kefford Richard , Kirkwood John M , Long Georgina V
Published: November 2019

Abstract not available.
Comparative Pharmacokinetic Profiles of a Novel Low-Dose Micronized-Isotretinoin 32-mg Formulation and Lidose-Isotretinoin 40 mg in Fed and Fasted Conditions: 2 Open-label, Randomized Crossover Studies in Healthy Adult Participants
Authors: Madan Sumit , Kumar Sudershan , Segal Jeanett
Published: November 2019

Abstract not available.
Acne-Related Quality of Life: Efficacy of a Novel Tretinoin 0.05% Lotion in Male and Female Patients with Moderate-to-Severe Disease
Authors: St. Surin-Lord Sharleen , Werschler William Philip , Guenin Eric
Published: November 2019

Abstract not available.
Acne-Related Quality of Life: Correlation Between Acne Symptom Scores and Other Domains Following Treatment with Tretinoin 0.05% Lotion
Authors: Woolery-Lloyd Heather C , Harper Julie C , Guenin Eric
Published: November 2019

Abstract not available.
Strategy Guidance and Counseling Comprehensive Based Spiritual Intelligence for Student in the Digital Era
Authors: Bhakti Caraka Putra , Rahman Fuad Aminur , Ghiffari Muhammad Alfarizqi Nizamuddin
Published: November 2019

The purpose of this paper is to discuss strategy guidance and counseling comprehensive based on spiritual intelligence for students in the digital age. Guidance and counseling comprehensive is part of education, which is also a model of guidance and counseling that adheres to the principle of developmental guidance and counseling. The basic assumption of the Guidance and development counseling approach is the idea that healthy individual development will occur in the healthy interactions of individuals with their environment. In other words, the environment for individuals becomes a learning environment, because there are various intelligences that need to be considered in the process of individual development and spiritual intelligence is one aspect of individual development that needs attention. Spiritual intelligence is the highest form of intelligence that combines the two previous forms of intelligence, namely intellectual intelligence and emotional intelligence. Spiritual intelligence is considered as the highest intelligence because it is closely related to people's awareness to be able to interpret everything and is a way to be able to feel happiness. Especially in the digital era, the era illustrates that the technological revolution phase has changed the way and human behavior in scale, scope, complexity, and transformation from previous life experiences, requires that every individual must have good spiritual intelligence, so that they can face the development of the digital era this dynamic well.
Knowledge Management Implementation in Muhammadiyah Elementary School
Authors: Fauzi Hafidh Nur , Mufti Umam
Published: November 2019

Knowledge Management is a systematic step in managing intellectual assets/knowledge and various information from individuals and organizations to be able to compete in order to add value and innovation. In the other hand, knowledge is one of the agency's assets and can be a separate competitive advantage if it can be managed properly. Current problems are technological developments and increased competition between educational institutions. If an educational institution does not have good knowledge management, of course, it will be left behind. Good management is needed and applied optimally. In Muhammadiyah Elementary School of Banguntapan, there are two management implementation aspects, namely identification of knowledge and identification of structures. Tacit and explicit factors as patterns of knowledge management development also require attention. If all of these factors are properly considered and applied, it will create a favorite school that has good knowledge management.
O EMPREENDEDORISMO SOCIAL COMO POSSIBILIDADE DE CIDADANIA
Authors: Oliveira Dias Dias
Published: November 2019

A chamada sociedade “pós-moderna” está instituída em um contexto social de uma complexidade existencial extremamente complexa, em que as relações sociais são envolvidas por lógicas, interesses e raciocínios deslocados totalmente do bem comum, uma ação arbitrária e particularizada que desconsidera toda e qualquer panorâmica presente no seu entorno, mesmo que ela represente uma pandemia de miserabilidade mundial dos indivíduos. Através da pesquisa bibliográfica, do debate crítico-analítico e uma abordagem exploratório acerca das questões que permeiam a constituição do Empreendedorismo Social, como forma de oportunizar a ver e a voz dos “invisíveis” socialmente, este estudo procura questionar o modelo de sociedade que se tem em curso atualmente.  A totalidade vigente não pode se manter, é insustentável a concentração de riqueza nesse “mundo moderno”, cabendo às camadas menos abastadas socialmente se unirem para superar essa problemática e a academia de mostrar-lhes o caminho a ser triado nesse ambiente infestado por “predadores vorazes” do capital.
PRÁTICAS CONTÁBEIS E PROCESSO DECISORIAL: UMA ANÁLISE COM OS PRODUTORES RURAIS DO PARANÁ
Authors: Viégas Mariana , Nogueira Daniel Ramos
Published: November 2019

O objetivo deste trabalho é verificar se os agricultores do município de Cambará-PR utilizam a contabilidade no processo decisorial em sua atividade. Para isso, foram aplicados questionários, caracterizando uma metodologia descritiva, por meio de um levantamento de dados. Pelos resultados apresentados, pode-se concluir que, a maior parte (90%) dos agricultores se utiliza de algum controle ou anotação. Cerca de 70% dos respondentes, buscam sempre separar as despesas particulares e as da atividade. A maior parte dos controles são para atender as obrigações fiscais/contábeis. Daqueles que fazem anotações, apenas 30% as utiliza para fins decisoriais. Estes resultados são convergentes com a literatura nacional e internacional sobre o assunto. Sugere-se que pesquisas futuras façam investigações sobre o processo de implantação das ferramentas decisoriais contábeis por períodos longos, analisando o impacto desta adoção.
ANÁLISE DA RECEITA TRIBUTÁRIA DIFERIDA DERIVADA DE PREJUÍZOS FISCAIS NA BASE DE CÁLCULO DO IRPJ E NO PAGAMENTO DE DIVIDENDOS
Authors: Gabrielli Guilherme Augusto Gonçalves , Pinto Leonardo José Seixas
Published: November 2019

Apesar das controvérsias acerca da receita tributária diferida derivada do Prejuízo Fiscal e sua distribuição como dividendos, esse estudo qualitativo mostra com base nas Leis, entendimentos da Secretaria da Receita Federal e dos acórdãos do CARF como proceder contábil e tributariamente. O Prejuízo Fiscal apurado nas empresas optantes pelo Lucro Real e que seguem as normas emanadas dos Comitês de Pronunciamentos Contábeis podem ser tratados como ativo fiscal diferido, desde que a empresa julgue ter lucro tributável no futuro para compensar esse Prejuízo Fiscal. A medida em que a empresa decide contabilizar esse ativo apura-se uma receita tributária diferida lançada na demonstração do resultado do exercício, aumentando o lucro do período. Essa receita deve ser excluída da base de cálculo do Imposto de Renda, mas pode compor o lucro líquido passível de distribuição aos acionistas sem qualquer ajuste. Por outro lado, no período seguinte em que se apurar Lucro Real, deve-se compensar o referido Prejuízo Fiscal respeitando o limite de 30% do Lucro Real antes de compensar os Prejuízos Fiscais e ao provisionar o Imposto de Renda deve-se abater desse passivo a parcela referente ao ativo fiscal diferido. Nesse momento, o entendimento é provisionar dividendos com base no lucro líquido apurado, mesmo sendo a despesa corrente com Imposto de Renda superior ao valor pago desse imposto.
MAKETING VERDE E COMPRA DOS CONSUMIDORES: ESTUDO DE CASO MÚLTIPLO EM SUPERMERCADOS
Authors: Costa Antonia Claudia dos Santos , Ribeiro Henrique César Melo , Moreira Antônia Amanda Alves Pereira
Published: November 2019

A presente pesquisa tem como objetivo compreender o envolvimento do marketing verde na escolha de compra dos consumidores. Para tanto foi realizada uma pesquisa qualitativa em três supermercados locais. Os procedimentos utilizados para coleta de dados foi o método da entrevista semiestruturada e da observação indireta, não participante. E como método de análise de dados, foi utilizado o estudo de caso múltiplo. Constatou-se que o consumo de produtos sustentáveis está, aos poucos, se tornando uma realidade, mas a relação existente entre consumidores e produtos sustentáveis ainda deixa a desejar, pois as práticas de compras dos consumidores são mais voltadas a produtos básicos. O marketing verde é considerado importante, mas as ações desenvolvidas para essa temática não são realizadas para atrair a atenção dos consumidores. Busca-se com a execução desse trabalho aumentar as fontes relativas ao tema de marketing verde, expondo as escolhas tomadas por consumidores além de enfatizar a importância do produto verde para a sustentabilidade ambiental. A realização dessa pesquisa trouxe como contribuições constatar que a temática ambiental é vista pelos entrevistados como um tema importante e apesar de uma pequena quantidade consumir esses produtos, as pessoas acreditam que o consumo desses produtos é bom para todos, além de contribuir com o meio ambiente.
CONTABILIDADE DE GESTÃO DA SUSTENTABILIDADE: REVISÃO SISTEMÁTICA DA LITERATURA MUNDIAL
Authors: Garcia Daniele Rodrigues , Pereira Junior Errol Fernando Zepka
Published: November 2019

A sustentabilidade tem sido alvo de inúmeros debates e estudos há décadas, no meio acadêmico, empresarial e governamental. Do ponto de vista comum, seu conceito está relacionado ao desenvolvimento sustentável universal, ou seja, a mesma é formada por atitudes ambientalmente corretas, economicamente viáveis e socialmente justas. Já a contabilidade de gestão da sustentabilidade é um termo que geralmente é utilizado para avaliar o alinhamento interno em relação às questões sustentáveis e melhorar o desempenho das organizações como um todo. Estudos sobre este tema apresentam amplitude, porém carecem de investigação focada para identificar, selecionar, avaliar e sintetizar as evidências relevantes disponíveis, oferecendo um panorama que sirva de base aos estudos futuros, bem como identificando lacunas que possam ser preenchidas por meio de novos estudos, no que se justifica a proposta do presente estudo. O objetivo geral deste estudo é levantar o panorama da produção acadêmica nos principais periódicos científicos sobre este tema através de uma revisão sistemática da literatura. O principal achado da pesquisa concentra-se em como a contabilidade de gestão da sustentabilidade tem sido estudada na literatura e quais as principais relações detectadas, sendo elas: contadores, controle e medição, gestão e desempenho.
IJTIHAD DAN KONTEKSTUALISASI HUKUM ISLAM
Authors: Sulthon Muhammad
Published: November 2019

Science and technology development now days has caused the problems faced by islamic society become more and more complex. The study on law product has to be counducted and reexamined for answering the problems and finding the solotions. Therefore, ijtihad one of the methods used by several mujtahids, either fardi ijtihad or jama’i ijtihad. A number of mujtahids from various diciplines are needed to make more reliable decisions.This article will describe the role of ijtihad in the process of islamic law formation.
IMPROVING COLLEGE STUDENTS’ SPEAKING SKILL THROUGH VIDEO PROJECT
Authors: Yusroh Mufidah
Published: November 2019

Technology is very much part of today’s life. It has been used as a tool in language learning throughout the world at all different levels especially adult learners. Nowadays, it is important to engage students to speak confidently and learn independently in their daily activity as students. However, the level of their speaking skills is still not satisfactory. They still have difficulty to communicate using English. The purpose of this study is to examine whether video project able to improve the speaking skill of the students.  A Classroom Action Research design was applied. The data were collected through small group and individual activities. Video project competition was done for the final project. This study was conducted in two cycles of seven meetings in each cycle. Based on the analyses, data showed that there are changes from cycle 1 to cycle 2. In cycle 1, the percentage of students English skill is 54% and it is increased become 75% in cycle 2. The average result of percentage in cycle 1 to cycle 2 is 21%. The result of the data showed that the use of video project could be one of the best alternatives to improve the students’ speaking skill.
PELAKSANAAN PENDIDIKAN KARAKTER DI M.I. MIFTAHUL ULUM TAMBAKREJO TONGAS PROBOLINGGO
Authors: Khosiah Nur
Published: November 2019

This research aims to study the value, the policy, the design, and also the application of character building education in Miftahul Ulum tambakrejo elementary school. The character building in Miftahul Ulum Tambakrejo elementary school consists of religious value beside independence and careness. In order the policy to be successful, the character building includes three points: 1) about learning such as giving more time for religion subjects, 2) the capacity building for teacher, 3) outside class activity such as supplying “my diary” book. The character building education in Miftahul Ulum Tambakrejo elementary school was applied inside and the classroom. The activity inside the classroom was applied with integrated model and strategy, namely integrated all the subjects with character value and related to the character in daily life. Meanwhile the approach used is inculcation approach. It is an approach that uses example in learning procces such as warshipping activities in the school. The character building outside the classroom was applied by having outbound, outdoor, extracurricular and worshipping custom. These activities will then be a good habit, so that the students always do positive thing.
Potencial da espécie invasora Cryptostegia madagascariensis em solos salinizados
Authors: De Medeiros Jailma dos Santos , Mesquita Francisco de Oliveira , De Andrade Leonaldo Alves , De Oliveira Cleiton José , De Souza Edlânia Maria
Published: November 2019

Resumo: Este trabalho foi conduzido em casa de vegetação com vistas a avaliar os efeitos da salinidade nas características químicas de dois tipos de solo, bem como sobre a emergência e desenvolvimento inicial de plantas de Cryptostegia madagascariensis. Primeiramente, o material de um Neossolo Flúvico e de um Vertissolo foi irrigado com água salina (0,3; 1,0; 2,0 e 4,0 dS m-1). Em seguida, foram acondicionados 19 kg de cada substrato em vasos plásticos com capacidade para 21 L. Os tratamentos foram arranjados em blocos casualizados, com quatro repetições, tendo sido retiradas amostras de solo de cada unidade experimental para análise. O experimento foi instalado com dez sementes por vaso e no 10º dia após a semeadura (DAS) realizou-se o desbaste, deixando quatro plantas por vaso. As variáveis avaliadas foram: emergência de plântulas, diâmetro do caule ao nível do solo, altura de plantas, número de folhas, área foliar e tamanho das folhas aos 152 DAS. O acréscimo da salinidade elevou os níveis de Sódio, Magnésio, Potássio, Percentual de Sódio Intercambiável (PSI), Razão de Adsorção de Sódio (RAS) e Percentual de Sódio Trocável (PST) em ambos os solos, com exceção do pH no Vertissolo. Foi verificado decréscimo na emergência das sementes no Vertissolo, porém, não se observou influência no crescimento inicial das plantas em ambos os solos estudados. O aumento do teor salino das águas de irrigação elevou o caráter salino dos dois solos estudados, porém não prejudicou o crescimento inicial das plantas jovens de C. madagascariensis até os 152 dias, o que indica que a espécie é tolerante à salinidade, explicando, em parte, o sucesso desta espécie em colonizar áreas salinas, representando uma vantagem ecológica da mesma.
Palavras chave: Invasão biológica, espécie exótica, Caatinga, germinação.
Genotypic variability of biochemical composition of fruits of introduced species of Ericaceae and Actinidiaceae families in conditions of Belarus
Authors: Rupasova Zh. A. , Garanovich I. M. , Shpitalnaya T. V. , Pavlovskiy N. B. , Goncharova L. V. , Vasilevskaya T. I. , Krinitskaya N. B. , Pavlovskaya A. G. , Pigul M. L. , Frolova L. V.
Published: November 2019

The article describes results of a comparative study of variability of 14 quantitative characteristics of biochemical composition of fruits in sort rows of 4 species of introduced varieties of Ericaceae (Oxycoccus macrocarpus, Vaccinium corymbosum) and Actinidiaceae (Actinidia arguta, Actinidia kolomikta) families, which has shown its lowest dependence on genotype in O. macrocarpus and the greatest dependence in A. arguta while the species studied have similarities in the level of genetic determinancy of a number of characteristics of fruits biochemical composition. It has been shown that the lowest stability in sort rows of both species of Ericaceae fam. is typical of parameters of accumulating anthocyanins proper and leucoanthocyanins while the greatest stability – that of ascorbic acid, which is characterized by high variability in both species of Actinidiaceae family. Most species of introduced plants studied have the lowest variability in sort rows in content of soluble sugars and total amount of bioflavonoids in fruits, while the greatest one – in sugar-acid index and tannins content. It has been found out that V. corymbosum and A. arguta have little dependence of flavonols content in fruits on genotype while V. corymbosum and A. kolomikta – that of pectin substances with a strong dependence of parameters of accumulating the latter in O. macrocarpus and A. arguta.
Application of internal control based on recombinant retroviral particles for increasing the PCR assay reliability
Authors: Fomina E. G. , Grigorieva E. E. , Scheslenok E. P. , Semizhon P. A. , Tkachev S. V. , Vladyko A. S.
Published: November 2019

Molecular diagnostic tests based on PCR preceded by reverse transcription (RT-PCR) are now used commonly for the detection of viral pathogens with RNA genomes. The application of internal controls to validate the entire process of these assays is necessary to prevent false-negative results caused by inhibition or inefficient extraction. In the present study a strategy to produce a new type of internal control for RT-PCR based on recombinant retroviral particles is described. Cell clones stably producing retroviral particles were established by transfecting GP+env-AM12 packaging cells with constructed MoMuLV-derived retroviral vector pLneo/gfp and subsequent cultivation on selective medium with G418. Theegfpgene was used as a target for primers and hybridization probe design for real-time RT-PCR assay and as a marker for flow cytometry analysis of eGFP expression by transfected cells. The developed internal control is stable and ribonuclease resistant, economical to produce, noninfectious and safe for routine use. It closely mimics the natural virus and could be successfully used to monitor all the stages of RT-PCR, including nucleic acid extraction, RNA reverse transcription and amplification.
Antimicrobial properties of Pseudotsuga menziesii essential oil
Authors: Kovalenko N. A. , Supichenko G. N. , Ahramovich T. I. , Feskova A. V. , Leontiev V. N. , Shutova A. G.
Published: November 2019

The steam distillation method was used to obtain samples of essential oil of Pseudotsuga menziesii introduced in Republic of Belarus. More than 20 components have been identified and determined in the essential oil of Pseudotsuga menziesii by gas liquid chromatography. The dominant components are bornylacetate (~25–30 %), camphene (~14–15 %), α-pinene (~7–8 %), β-pinene (~8–10 %). Distribution of the enantiomers of the main components of Pseudotsuga menziesii essential oil are shown. It was determined the optical purity of oil to (–)-bornylacetate. The antimicrobial activity of Pseudotsuga menziesii essential oil was detected in relation to test cultures of gram-positive and gram-negative bacteria. Gram-positive bacterial cultures were more sensitive to the inhibitory effect of essential oil. The effect of the optical activity of essential oil dominant components on antimicrobial properties is shown.