bluuebunny/crossref_metadata_2025 huggingface dataset:
Manipulation of task constraints on throwing of amateur handball athletes
Authors: Ribeiro Gabriel A. , Spinola Pedro H. B. F. , Tucci Helga T. , Carvalho Raquel P.
Published: June 2021

BACKGROUND: In handball, speed and accuracy are essential characteristics for the performance of throwing.
AIM: To verify the effects of manipulation of task constraints during the throws on kinematic variables in amateur handball players.
METHOD: 18 amateur handball players (18-27 years) made 10 throws to the target with a focus on speed and 10 throws with a focus on accuracy. The kinematic analysis of the throwing was performed, and the Student's t-test was used.
RESULTS: Greater velocity, and hand, acromion, and iliac spines trajectories for throws with a focus on speed in cocking phase was observed. During the acceleration phase, there was greater velocity, and trajectory of the right upper posterior iliac spine, and less time and hand, acromion, and left upper posterior iliac spines trajectories for throws with a focus on speed. The throw with a focus on speed showed greater shoulder and elbow angles at the beginning, and greater elbow angle at the end of throwing.
CONCLUSION: The manipulation in the focus of the throw influenced the movement strategy from the cocking phase to the acceleration phase according to the movement intentionality, with most of the variables presenting greater values in the throw with a focus on speed.
Young adults’ physical activity and physical function: 12 months follow up
Authors: Silva Bruno , Bezerra Pedro , Cancela José Maria
Published: June 2021

BACKGROUND: The knowledge about university students generally demonstrates that they do not meet current recommendations for Physical Activity (PA). However, PA and Physical Fitness are not an indicator for Physical Function (PFn), being PFn a separate construct that is related to movement skill proficiency.
AIM: To analyze the rate of changes in PFn accessed by the Functional Movement Screen (FMS) and PA levels (sports and leisure) in a group of Sport Science university students after one year.
METHOD: 41 men (22.3±5.7years) and 22 women (20.7±0.9years) participated in this research. The data were collected in the first month of the academic year and after 12 months in the following order: Baecke Habitual Physical Activity Questionnaire, anthropometrics, and FMS.
RESULTS: PFn assessment, from baseline to second assessment, revealed significant changes in Trunk Stability Push-up (p=0.003; ES=0.656) and total score (p=0.026; ES=0.497) for women and in Deep Squat (p=0.003; ES=0.334) for men. No significant changes were found in women PA levels. Men decreased in leisure PA (p=0.002; ES=0.538) and total PA (p=0.003; ES=0.519).
CONCLUSION: Sports Science university students’ daily routines may mediate physical activity patterns with following physical function improvements or decrements, occurring due to contextual environments that over-or under-produce the stimulation required to develop those skills.
Dobrar a morte, despossuir a violência
Authors: Costa Pablo Assumpção Barros , Greiner Christine
Published: June 2021

O objetivo deste artigo é indagar como a performance, não apenas responde e ilustra condições necropolíticas, mas pode ativar narrativas silenciadas e espectros de mundos que pareciam inadmissíveis. Para tanto, contextualizamos o debate proposto por Achille Mbembe, em diálogo com autoras como Judith Butler e Denise Ferreira da Silva; e, em seguida, analisamos a videoperformance Aiku’è (R-existo), de Zahy Guajajara e a performance coreográfica “Gente de Lá”, criada por Wellington Gadelha.
Performance e contra-argumentos artísticos anticoloniais em Nuestramérica
Authors: Villalobos Herrera Álvaro
Published: June 2021

O artigo apresenta características do cenário econômico, político e social da América Latina. De forma crítica e do ponto de vista da arte, aponta o autoritarismo, os abusos de poder e a corrupção cometidos pelos governantes dos países da região. Apresenta-se o compromisso de dois artistas da Venezuela e do México com obras que abordam as relações entre as formas de pensamento e ação derivadas do colonialismo interno e do capitalismo como modo de produção que promove o crescimento armamentista, a necropolítica e o desprezo pelas formas de produção em bases comunitárias.
A gente combinamos de não morrer
Authors: Oliveira Victor Hugo Neves
Published: June 2021

Este artigo busca discutir como o racismo estruturado na sociedade brasileira funciona como poderosa tecnologia cultural que fundamenta privilégios e exclusões no panorama da vida social. Nosso interesse é compreender as articulações desenvolvidas por grupos dominantes na elaboração de projetos raciais determinantes para a consolidação das desigualdades institucionalizadas. Além disso, pretendemos analisar procedimentos estéticos que partam de temáticas relacionadas à dominação racial e à necropolítica.
Os tempos de escuta
Authors: Barría Jara Mauricio
Published: June 2021

A partir do que poderíamos chamar de fenomenologia da escuta, desejo traçar um mapa de alguns marcos que descrevem o outubro chileno passado, no qual podemos apreciar uma tensão entre modos de experimentar o tempo de ocupação da cidade. Diante do tempo de produção e administração eficientes do trabalho, surgiu um tempo longo e subversivo, que interrompe a lógica da eficiência, à qual se contrapõe o tempo do controle do estado de exceção. Pensar a “explosão social” como uma insubordinação do tempo, permite compreender de outro lugar a dinâmica do corpo e da experiência que se realiza neste processo social no Chile e nos faz presentes no lugar da escuta como o nó sobre o qual podemos levantar uma crítica aos fundamentos de representatividade de nossas democracias atuais. Finalmente, a ação do grupo feminista LasTesis, “Un violador en tu camino”, oferece um bom exemplo desse tipo de insubordinação.
Saberes pandémicos para intentar imaginar lo que vendrá
Authors: Diéguez Caballero Ileana
Published: June 2021

Cuando lanzamos la convocatoria para este número de Conceição | Revista Concepción, pidiendo “explorar las diferentes formas en las que el pensamiento crítico, las artes y el desempeño social o ciudadano - particularmente en América Latina - se comprometen o reinventen para responder a los desafíos nuestro tiempo ”, no podíamos imaginar lo que vendría ni la magnitud de la crisis que estamos viviendo. En ese momento comenzaron a circular las primeras reflexiones: Sopa de Wuhan (ASPO - Aislamiento Social Preventivo y Obligatorio, marzo de 2020), Pandemia y capitalismo (FilosofíaLibre, abril de 2020), Todo lo que nos cae encima (LA RECI) Ediciones & OnA, San Cristóbal de las Casas, México, 2020), entre muchos otros. Un año antes, Ailton Krenak había publicado Ideas para posponer el fin del mundo (Companhia das Letras, 2019), que, en definitiva, y desde la perspectiva de Viveiros de Castro, “reflexiona sobre los supuestos antropológicos de esa civilización que está convirtiéndose en el buque insignia de la 'humanidad' y sobre los efectos que está teniendo sobre las condiciones materiales y espirituales de existencia de todos los pueblos, especies y seres existentes en la Tierra ”(VIVEIROS DE CASTRO, 2020).
Waldemar Cordeiro e a Arteônica
Authors: Arantes Priscila
Published: June 2021

Na passagem dos anos 1960 para os 1970, o artista brasileiro Waldemar Cordeiro (1925-1973) desenvolve suas primeiras obras em computer art a partir da aplicação do conceito matemático de “função derivada”. Na mesma época, organiza e participa de mostras e desenvolve uma série de ensaios antevendo que a utilização de recursos digitais seria um processo inevitável para o futuro da recepção da informação e da comunicação artística. Um olhar atento para a produção artística e teórica de Waldemar Cordeiro, depois de quase cinquenta anos de suas primeiras investidas no campo da arte e tecnologia, é uma excelente oportunidade não somente para revisitarmos sua trajetória, mas também para reescrevermos a história da arte digital e do pensamento sobre ela, colocando o Brasil e a América Latina em lugar central, e não periférico, em relação às narrativas europeias e estadunidenses. Waldemar Cordeiro e a Arteônica: reescrituras da arte digital no Brasil e na América Latina divide-se em três momentos. No primeiro, faremos uma pequena aproximação entre os teóricos da estética informacional e os ensaios de Waldemar Cordeiro, especialmente a partir de um dos seus textos mais instigantes, Arteônica, publicado no início dos anos 1970. No segundo momento, realizaremos uma breve leitura sobre a fase concretista e do concretismo semântico (ou popcretos) de Waldemar Cordeiro; discussão fundamental para o entendimento das questões colocadas pela fase da computer art (1969-1973). Para finalizar, analisaremos suas obras em arteônica no sentido de destacarmos as características de sua produção e sua relação com o contexto do país.
Modelos involuntarios
Authors: Vanegas Carolina
Published: June 2021

Víctor de Pol (1865-1925) fue un escultor veneciano radicado en Argentina a fines del siglo XIX, reconocido por sus trabajos de escultura ornamental y conmemorativa. Una de las facetas menos exploradas de su obra es la escultura de tema étnico. En el presente artículo se analizan las fuentes, iconografía, exhibición y recepción de las pocas obras en las que De Pol trabajó este asunto. El objetivo es señalar algunas de las contradicciones que surgieron en la creación y recepción de estas obras en el cruce entre los nacientes estudios antropológicos y etnográficos y la construcción del Estado-nación en Argentina.
Southeast Asian biennales
Authors: Veiga Leonor
Published: June 2021

This text aims to give an overview of existing biennials in Southeast Asia. By adopting a national perspective, it describes the genesis, the continuation (or not) and the programmatic character of regional biennials. The text proposes that the idea of perennial exhibition can be traced to the 1970s, when the ASEAN started to promote regional events, in an attempt to create unicity through culture. As this project lost vitality, it was substituted for biennials in Southeast Asia and in the Asia-Pacific region. According to the reasons behind their genesis, some biennials that were established in Southeast Asia follow the biennale model while others follow the model of resistance biennales. This shows variety and regional independence toward the global world.
Assembling and disassembling
Authors: Sternfeld Nora
Published: June 2021

“Towards the end of the first decade of the twenty-first century”, as Anthony Gardner and Charles Green propose, “biennials became self-conscious.” Increasingly they are reflecting on themselves as "hegemonic machines" (Oliver Marchart), and for this very reason also understand themselves as places of intervention. We have to come to terms with the fact that biennials today are both: "Brands and Sites of Resistance", "Spaces of Capital and Hope" (Panos Kompatsiaris).The article follows withdrawals and protests as well as interventions and strategies of appropriation of biennials in the second decade of the 21st century. Protests in St. Petersburg, Sydney and New York shape the biennials they boycott. In Kochi, Athens, Dhaka, and Kassel we encounter curatorial projects that challenge the apparatus of value coding. The relationship between bottom up and top down often becomes blurred. In Prague, Warsaw, Kiev, and Budapest it is even reversed. Here biennials are used as a means of counter-hegemony and institutional survival.
PENGARUH MIKROORGANISME TERHADAP PRODUKTIVITAS ENERGI LISTRIK MFC DENGAN VARIASI LIMBAH PABRIK TAHU DAN LIMBAH PERIKANAN
Authors: NOVRIANDY MUHAMMAD
Published: June 2021

Energy is a very fundamental necessity in human life. Current energy usage is highly dependent on the surrounding environment. Especially in remote areas, which require simple energy instruments such as batteries or fuel cells. The Fuel cell is an energy instrument that transfers electricity from a rechargeable source using external materials. Microbial Fuel Cell (MFC) is an alternative form of environmentally friendly energy that is commonly used as a source of energy in the future. MFC is an energy instrument that can convert chemical energy into electrical energy through catalytic reactions by utilizing microorganisms. Plant waste tofu and fishery waste is a waste that contains a lot of carbohydrates, proteins, and fats that usually cause heavy pollution to the waters. By utilizing the liquid waste itself is one way of solving problems in the environment and lack of energy by using the MFC system. For the experiment, this time aimed to compare the electrical energy generated between waste plant tofu and sewage fisheries. In a strong MFC experiment current on plant waste knows an increase as much as 1.47% of fisheries waste, while for voltages in the trial MFC waste fisheries have increased by 1.19% from tofu plant waste.
Social impacts of modernisation in the choice of tourist destination
Authors: Banovac Boris , Boneta Željko
Published: June 2021

This work deals with the influence of the socio-cultural factors in the tourist' decisions upon the choice of tourist destinations. The author's attention is primarily directed towards the analysis of social background consisting of "uncontrolled marketing variables" which are essential in the segmentation of the tourist product of destination. The work is composed of two parts. The introductory, theoretical part refers to the analysis of the socio-cultural atmosphere in which the attitudes, the aspirations and the needs influencing the tourist conduct are shaped. In the other, empirical part of the work the authors analyse the results of the longitudinal research of the socio-cultural aspects of the tourist demand made in the period between 1994. and 1997. in the hotels in the istrians district. The influence of the publicity means in the choice of istria as a tourist destination is examined in correlation with socio-cultural and demographic variables such as: sex, age, qualification, profession, as well as in the context of the modernising processes in the emitting countries. The special aspect of the research is presented by the socio-linguistic analysis of the slogans which, in the opinion of the tourists, express the peculiarity of the Istrian tourists product best. By this, the experienced dimension of the Istria as a destination is affected.
MARKET POSSIBILITIES FOR THE DEVELOPMENT OF AGROTOURISM IN ISTRIA
Authors: Bošković Desimir
Published: June 2021

The basic question for further development of our tourism is a how, what with and when to restructure the mass tourist supply and make it flexible to market trends and demands. In the developed countries, the transformation of mass tourism to various selective forms and kinds of tourism is under way and very successful. The development of agritourism, which this paper is about, could significantly alleviate the past discrepancies in tourist supply and change the structure of the whole supply. On basic of the research done, the authors claim that some basic conditions for the development of agritourism in Istria have been fulfilled. So ther suggests its concept of development, financial funds needed, ways of financing, stimulative and other measures, legal regulations needed, organization of marketing activities, effects of the development etc.
White Cord Syndrome and Acute Tetraplegia After Posterior Cervical Decompression
Authors: Segal Dale N. , Lunati Matthew P. , Kukowski Nathan R. , Michael Keith W.
Published: June 2021

Case:

A 55-year-old man undergoes posterior cervical decompression and instrumentation for progressive cervical myelopathy and develops white cord syndrome (WCS) postoperatively with acute tetraplegia.

Conclusion:

WCS is a rare complication of spinal surgery that is thought to be due to reperfusion injury. We diagnosed WCS in our patient through postoperative examination consisting of acute tetraplegia and magnetic resonance imaging revealing increased signal in the cord. In this case, we used intravenous dexamethasone and mean arterial pressure above 90 mm Hg resulting in markedly improved clinical examination.
Acute Gluteal Compartment Syndrome with Nonclassical Symptoms
Authors: Davis Benjamin J. , Mak Ryan , Schneider Andrew , Brown Nicholas M.
Published: June 2021

Case:

A 34-year-old man presented to the emergency department with rhabdomyolysis, acute kidney injury, and pain in the gluteal region after falling asleep on his side after heroin and alcohol use. On examination, he had swollen gluteal compartment musculature; however, he tolerated full passive range of motion with minimal pain. Intercompartmental pressure measured >110 mm Hg; therefore, emergent fasciotomy of the gluteal compartment musculature was performed. Timely treatment of his acute compartment syndrome produced minimal functional deficits with a favorable outcome.

Conclusion:

Clinicians should be vigilant in the setting of patients with prolonged gluteal pressure, particularly with alcohol or drug use, to avoid potential serious complications of a missed acute compartment syndrome diagnosis and be aware that every case may not have all of the components of the classic presentation.
Experimental study of supercontinuum generation in step-index highly nonlinear fibers
Authors: gao weiqing , Zhang Lei , Chen Haiwen , Li Jingya , Jiang Yuxi , Wan Lipeng , Dai Wenwen , Chen Wu , Tong Liang , Liu Shaoqing , Zhou Yong , Ma Xiaohui
Published: June 2021

In this work, supercontinuum (SC) generation in three kinds of step-index highly nonlinear fibers (HNLFs) are experimentally investigated. The generated SC spectra are compared with each other by changing the numbers and wavelengths of the pump sources, and also by employing the HNLFs with different refractive-index differences between the core and the cladding. The widest spectral range of generated SC was about 2650 nm covering from 350 to 3000 nm when using the three pump wavelengths of 800, 1400 and 1867 nm. The results demonstrate that the step-index HNLFs have excellent performances for SC generation and great potentials for the realization of all-fiber SC source.
Complete Genome Sequence of Microbulbifer sp. YPW1 from Mangrove Sediments in Yanpu Harbor, China
Authors: Dingquan Wang , Wang Jianxin , Shui Bonian , Zhu Longqiang , Wang Jiangqi , Jin Linxi , Qu Wu
Published: June 2021

In this work, a strain named YPW1 was isolated from the sediments of an artificial mangrove in Yanpu harbor, China. Whole genomic sequencing was conducted to reveal the potential ecological roles of strain YPW1 for the environment. The result of 16S rRNA gene alignment assigned strain YPW1 into Microbulbifer genus, and then, 10 representative genomes from Microbulbifer genus were selected to compare with YPW1. Results showed that the genome of strain YPW1 possessed more carbohydrate-active enzyme genes to transform various recalcitrant polysaccharides into bioavailable monosaccharides than those of the selected genomes. Furthermore, among the selected genomes, YPW1 was the only strain with nitrate, nitrite, and nitric oxide reductases which could appoint nitrous oxide, a powerful greenhouse gas, as the end-product of its denitrification process. Therefore, strain YPW1 was a member of Microbulbifer genus with special ecological roles that served as the center for the degradation and utilization of polysaccharides and the performer of denitrification with greenhouse gas as the end-product, and the abundance and biological activity of YPW1 could be an indicator to reflect the ecological function of this artificial mangrove in energy material providing and climate regulation.
Sox10 Gene is Required for the Survival of Saccular and Utricular Hair Cells
Authors: Qi Jing-cui , Jiang Qing-qing , Ma Long , Yuan Shuo-long , Sun Wei , Yu Li-sheng , Guo Wei-wei , Yang Shi-ming
Published: June 2021

Background:. Pathological changes of the cochlea and hearing loss have been well addressed in Waardenburg syndrome (WS). However, the vestibular organ malformation in WS is still largely unknown. In this study, the differentiation and development of vestibular sensory epithelium and vestibular function caused by SOX10 mutation, a critical gene induces WS, has been studied in minature pig model. Results: Degeneration of vestibular hair cells was found in this Sox10 mutation porcine model. Inner ear phenotype of the SOX10+/R109W miniature pigs showed cochlear abnormalities as well as saccular hypofunction. In the mutant pigs, no prominent dissimilarity was shown in the bone structure of the semicircular canals. However, the saccular membrane was collapsed and the infusion of stereocilia of the hair cells were observed. There was no dark cells in the uticules in th mutant pigs. The density of the utricular hair cells was also significantly lower in the mutant pigs compared to the wild type. Conclusions: Our study demonstrated that the SOX10 gene and melanocytes play important roles in the vestibular organ development. Sox10 mutation disrupts the KIT-DCT signaling pathway, affects the development of melanocytes and leads to vestibule morphogenesis.
Violence and Mental Health among Adolescents in South East Nigeria
Authors: Ughasoro Maduka D , Onukwuli Vivian Ozoemena , Onwujekwe Obinna E , Uzochukwu Benjamin S.C , Ebenso Bassey , Okoli Chinedu C. , Achor Achor F.
Published: June 2021

BackgroundThere is rise in the prevalence of mental health illnesses among the adolescent and the impact of violence on this rising trend requires to be evaluated. This is the aim of this study.Methods.The study was a cross-sectional school based study. Adolescents in the selected schools were interviewed using structured questionnaire. Information on the previous experience of violence, the action they took, and the effect on them were collected. Data was entered and analyzed using SPSS. Significant was set at the p-value of <0.05.ResultsA total of 716 adolescents were involved in the study. The prevalence of violence was 87%. About 57.2% of the violence occurred at home, 44.2% done by relatives and 49.2% within the past 6 months. Sexual abuse was 10.2%. Among the adolescents that experienced violence, 58.7% suffered some form of mental health illness(es). There was significant difference between the action the adolescents took after the violence incident and the action their considered appropriate (p=0.00001). Female gender (p=0.042), not living with parents (p=0.015) and poverty (p=0.00001) significantly correlate with adolescent violence.Discussion and Conclusion.Violence is high among adolescent and associated with high prevalence of mental health illnesses. Intervention to reduce violence should target improvement in poverty alleviation programs to empower families to carter for their children should be implemented.
Therapeutic Interventions are Important Risk Factors for Delirium in the ICU Setting ： A Multicenter Observational Study
Authors: Liu Ying , Yuan Zhiyong , Cai Shixia , Han Xiaoning , Song Kai , Wang Mei , Teng Haifeng , Sun Yunbo , Xing Jinyan
Published: June 2021

Background

Delirium is an important independent predictor of negative clinical outcomes in intensive care unit (ICU) patients. The purpose of this study was to investigate the territorial incidence of ICU delirium, its related risk factors, and short-term outcomes in Shandong Province, China, to provide precise information for territorial patient management.
Methods

A multicenter prospective observational study was conducted. Patients with delirium were defined as any patient with at least one positive CAM-ICU or ICDSC assessment. Demographics, admission clinical data, daily interventions provided to patients and environmental factors were collected.
Results

From May 1, 2018 to Jan 31, 2020, 536 noncomatose patients were ultimately eligible for the study. One hundred eighteen patients (22%) experienced delirium at least once. In the univariate analysis, age (p = 0.009), SOFA score (p = 0.006), a history of cerebrovascular disease (p = 0.044) and impaired renal function (p = 0.003) were risk factors for delirium. Most therapeutic interventions were linked to delirium in the univariate analysis, including enteral nutrition (p = 0.000), artificial airway (p = 0.021), nasogastric tube (p = 0.001), use of restraint straps (p = 0.000), and use of sedative medications, including midazolam (p = 0.003), propofol (p = 0.032) and butorphanol (p = 0.028). Among the patient’s vital signs and laboratory examinations performed on the day of assessment, body temperature, BUN levels and CRP levels were risk factors for delirium. Midazolam use, chronic renal insufficiency, physical restraints, nosogastric tube, enteral nutrition, and CRP and BUN levels were factors associated with an increased risk of delirium in the multivariate analysis. The durations of mechanical ventilation and ICU stay in patients with delirium was significantly higher than those in patients without delirium [8 (IQR: 4–14) vs 5 (IQR: 3–10) and 9 (IQR: 4–17) vs 6 (IQR: 4–12), p < 0.05].
Conclusions

Delirium was associated with prolonged mechanical ventilation and a prolonged ICU stay. Based on the findings from this study, we should not only reduce the use of sedatives and analgesics but also minimize invasive operations, including the placement of nasogastric tubes, to recover eternal nutrition for ICU patients and avoid physical restraints as much as possible to prevent delirium.
Trial registration:

This study was registered in the Chinese Clinical Trial Registry (ChiCTR1900021360).
Robust Dual-Channel Disturbance Rejection Attitude Control for a Quadrotor UAV: Theory and Experiment
Authors: Pan Jian , Xiong Jiaxin
Published: June 2021

In this paper, a robust dual-channel disturbance rejection control based on an inner-outer loop control framework is proposed for the attitude control of the quadrotor under modeling uncertainties and unknown disturbances. In the outer loop, a tracking differentiator is introduced to obtain smooth tracking signals and their derivatives. In addition, an outer loop controller is developed with the tracking signals set as the desired signals. In the inner loop, a robust dual-channel disturbance rejection controller based on a sliding mode observer is constructed, which contains an inner disturbance rejection channel (IDRC) and an outer disturbance rejection channel (ODRC). In the IDRC, a disturbance rejection compensator is designed to obtain the disturbance compensation values and to compensate a part of the lumped disturbances in the attitude dynamic model. In the ODRC, an inner loop controller with variable-gain switching terms and constant-gain switching terms is designed, whose switching terms are used to compensate the remaining part of the lumped disturbances in the attitude dynamic model. By using the proposed control scheme, the robustness is guaranteed, and the chattering phenomenon caused by the variable-gain switching terms is greatly reduced. The stability of the proposed scheme is analyzed by using the Lyapunov theory. Finally, the effectiveness is tested by the platform experiments.
Role of Human Papillomavirus and its Association with an Indian Oral Squamous Cell Carcinoma Subjects
Authors: Patel Amisha , Gupta Vijay , Shah Sejal
Published: June 2021

Oral Cancer; especially Oral Squamous Cell Carcinoma (OSCC) is the eighth most common cancer all over the globe and most common neoplasm in India. Due to the tobacco addiction pattern in Indians specially Guajarati’s are well known for high consumption of tobacco in non-smoking form may have the high-risk for developing oral cancer. Apart of this, Human papilloma virus(HPV) might be one of the cause for developing oral cancer hence, the proposed study was carried out for 50 primary OSCC subjects from January 2018 to October 2018. Tumour specimens were HPV-genotyped by type specific PCR method. Statistical analyses were performed by Fisher’s exact test. The present study identified 4% HPV infection frequency in advanced staged OSCC Indian subset, where One OSCC stage IV patient observed with HPV 16 infection and one OSCC stage III patient with HPV 18. Our finding differs with rest of the population, as the region have high amount of consumption of tobacco. Current study need to be validated in larger sample size to get the clear view for association of HPV with oral cancer.
Design of experiments for light-speed invariance to moving observers
Authors: Chen Qian
Published: June 2021

The principle of the constancy of the velocity of light, which stated that the light velocity is invariant to the motion of the emitter, was well established and directly proven by many experiments. Interestingly, the further assumption that the light velocity is also independent of the motion of the observer was, arguably, never conclusively proven by any experiment for a century. This paper tried to address some perceived technical difficulties in such experiments and proposed two experiments to test this assumption. One is to directly measure the light speed as to moving sensors, with the setup designed in such a way that the concerns of time synchronization and dilation can be avoided. Another experiment is to test the isotropy of the light speed to a high-speed particle by measuring the momentum to acceleration ratio. The experiment results, if positive, will provide direct proof of the assumption. Otherwise, it may imply a need for further investigation. Since the light speed invariance to moving observers is a key assumption of some fundamental physical theory, either way, the experiments will have significant importance.
How To Culture Limnoterrestrial Heterotardigrades: A Case Study In The Echiniscus, Pseudechiniscus And Viridiscus Genera
Authors: Momeni Sogol , Fuentes-González Jesualdo Arturo , Pienaar Jason
Published: June 2021

Background: Tardigradologists have long tried to culture limnoterrestrial heterotardigrades without success. This is likely because they depend on specific conditions in their microhabitats. Most limnoterrestrial heterotardigrades are found associated with bryophytes and lichens (collectively cryptogams). In contrast to eutardigrades, many of which are easily cultured, heterotardigrades are found in cryptogams that prefer drier and sunnier habitats and that tend to grow on the vertical surfaces of boulders, cliffs, or tree trunks. By carefully observing heterotardigrades in the Echniscus and Viridiscus genera over many months, we determined that these organisms feed on chloroplasts and cytoplasm of both moss cells (typically moss protonema) and single-celled green algae associated with the moss (typically Chlorella vulgaris). We also determined that the cryptogams they associate with, and hence the heterotardigrades themselves, spend more time in a dried state than most eutardigrade species. Taking these observations into account we varied food, water, and desiccation cycle conditions with the aim of developing a culturing protocol for heterotardigrades. Results: We have maintained laboratory cultures of several generations and counting of Echiniscus, Pseudechniscus and Viridiscus genera tardigrades using the following experimentally derived protocol: Both moss and algae from their natural habitats are required as food sources and a small layer of rain or spring water is added every morning and allowed to evaporate some overnight. Furthermore, the organisms are more likely to lay eggs on a dense mat of moss protonema, grown by inserting tips of moss branches into a solidified KCM / agar medium. The medium also provides a walking substrate for the tardigrades, and possibly a source of cations. Crucially, the cultures must be allowed to dry out completely every ten days for a period of at least three days. Moss in the culture dish significantly improves the chances of the tardigrades coming out of their desiccation-resistant states successfully. Conclusions: We conclude that periodic drying out, moss and algae are all required to successfully culture heterotardigrades. Furthermore, drying must occur slowly, and the moss protonema enables this by retaining moisture thereby slowing evaporation. We suspect our protocol will work for most limnoterrestrial heterotardigrades with minor tweaking of culturing conditions.
The Resistive Ground Fault of PWM Voltage Inverter In The EV Charging Station
Authors: Zurek-Mortka Marta , Szymański Jerzy Ryszard
Published: June 2021

During the direct touch of the inverter output voltage, the nonsinusoidal ground currents with a basic harmonic frequency between 1.5 kHz and 16 kHz, flow via a human’s body. Here was proved that Residual Current Device (RCD) type AC/IΔn = 30 mA does not switch off the power supply when a ground current with a value of about some hundred milliamps occurs. Because RCDs do not disconnect the power supply, the touch on the inverter’s voltage is dangerous to the health and life. For the authors, RCD usage in Voltage Frequency Converters is not a good engineer practice. The article presents tests of RCD operation in the event of a ground fault during EV battery charging.
Efficacy of Rikkosan For Primary Burning Mouth Syndrome: A Retrospective Study
Authors: Hato Hiroyuki , Sakata Ken-ichiro , Sato Jun , Asaka Takuya , Ohga Noritaka , Yamazaki Yutaka , Kitagawa Yoshimasa
Published: June 2021

Background

Burning mouth syndrome (BMS) is a chronic condition characterized by pain in the oral cavity. Kampo medicine is a traditional Japanese medical system, which has its roots partly in ancient Chinese medicine. The purpose of this study is to evaluate the efficacy of rikkosan—a traditional Japanese herbal medicine (kampo)—in the treatment of primary BMS.
Main body:

A single-center retrospective study was conducted in 32 patients who were diagnosed with primary BMS and treated with rikkosan alone through gargling (2.5 g rikkosan dissolved in 50 mL hot water) three times daily. Patients were asked to evaluate their pain using the numerical rating scale (NRS) at first visit, after 1 month, and the end of rikkosan treatment. One patient had stomatitis as a side effect after gargling with rikkosan, however, no side effects were observed in other patients. Overall NRS scores decreased significantly between the first visit (7.6 ± 2.7) and the end of treatment with rikkosan (4.4 ± 3.3).
Conclusions

Rikkosan may be an effective treatment for primary BMS.
Analysis of Codon Bias in Mitochondrial Genome of Epinephelus Fuscoguttatus
Authors: Bai Lirong , Lu Lili , Li Suping , He Jicui , Chen Jian , Wang Pei , Guo Yin , Wang Hongchen , Yu Dahui
Published: June 2021

Background: Epinephelus fuscoguttatus is one of the rare marine economic fishes with high economic value. At present, the researches on grouper mainly focus on artificial propagation, physiology and biochemistry, diseases and so on. However, there are few reports on mitochondrial genome level. The research aimed to analyze composition characteristics and usage preference of codon of mitochondrial genome in E. fuscoguttatus, and explored main factors of affecting the formation of codon preference, thereby providing theoretical basis for studying species evolution, genetics and breeding, and improving expression efficiency of exogenous genes. Results: GC content of mitochondrial genome of E. fuscoguttatus changed between 44.00% and 46.30%, with 45.40% of mean. Change range of CAI value was between 0.125 and 0.202, and the mean was 0.155. Effective number of codons (ENC) changed between 36.08 and 49.55, with 44.98 of mean. There were 32 codons that relative synonymous codon usage (RSCU) was more than 1, mainly ended with A/C. ENC-plot analysis found that all the genes were in the lower middle of the standard curve, and there was larger difference between actual and theoretical ENC, illustrating that codon bias was mainly affected by the choice. Correspondence analysis showed that the first axis contributed 58.85% of the difference, while the second, third and fourth axes contributed 14.59%, 7.66% and 5.43% of the difference respectively. Cumulative contribution rate of the first four vectors was 85.53%. Finally, nine optimal codons were selected: CUU, AUC, GUU, CCU, GCA, UAU, CGC, AGC and GGC.Conclusions: Codon usage preference of mitochondrial genome of E. fuscoguttatus was weak, and it preferred to use A/C terminated codon, and preference was mainly influenced by choice.
Effect of Electro-Acupuncture on Gut Microbiome in Cisplatin-Induced Premature Ovarian Failure Mice
Authors: He Qi-da , Guo Jing-jing , Zhang Qi , Yau Yuen-ming , Yu Yue , Zhong Zheng-hong , Tong Zi-yan , Yang Zong-bao , CHEN MIN
Published: June 2021

Background

Growing evidences showed that gut microbiota is associated with premature ovarian failure (POF). Many case reports had shown that electro-acupuncture was effective in the treatment of POF. However, there was little research on regulating gut microbiome of POF mice by electro-acupuncture. Therefore, this study aimed to verify whether electro-acupuncture could improve ovarian function and regulate gut microbiome in mice with POF. In addition, the therapeutic effects of electro-acupuncture at acupoints and non-acupoints were compared.
Methods

POF mice were established by injected intraperitoneally with cisplatin (2mg/kg) for 2 weeks. Guanyuan (CV4) and Sanyinjiao (SP6) were selected in the electro-acupuncture at acupoints group (EA group). Non-acupoints which around CV4 and SP6 were selected in the electro-acupuncture at non-acupoints group (EN group). EA group and EN group were treated for 3 weeks. The ovarian function was evaluated by assays of histopathological and molecular. Meanwhile, the gut microbiome of POF mice was detected by 16S rDNA sequencing.
Results

The results showed that EA could restore the estrous cycle and reduce the number of atresia follicles in POF mice. The levels of serum follicle stimulating hormone and luteinizing hormone were decreased by EA. As well as, the levels of serum estradiol, anti mullerian hormone and β-glucuronidase were increased by EA. The relative expressions of PI3K, AKT and mTOR were increased to promote the proliferation of ovarian cells in EA group. According to the results of 16S rDNA sequencing, we found that the diversity of gut microbiome in mice with POF was changed. However, the abundance and diversity of gut microbiome could be regulated by EA in POF mice. The relative abundance of beneficial bacteria was increased by EA. The KEGG pathway analysis showed that the gut microbiome which associated with estrogen signaling pathway, oocyte maturation and PI3K-AKT signaling pathway were regulated by EA.
Conclusions

EA could provide protection against cisplatin-induced ovarian damage. The abundance and diversity of probiotics could be increased by EA. Moreover, EA might treat POF via regulating the gut microbiome.
Solitary Thyroid Nodule High Incidence of Thyroid Cancer
Authors: Nasr Burkan , Qubati Mohammed , Qubati S , Al-Tamimi Abdulhakim , Rabo Yasser Abd , Gonid Anwar , Tam Abdulfatah Al , Al-Shujaa Mohamed , Nasr Burkan
Published: June 2021

The Aim: The preoperative distinguish between benign and malignant in solitary thyroid nodule is important. It helps to avoid unnecessary surgery and its adverse effects, such as hypothyroidism, hypocalcemia, and recurrent nerve injury.Methods: descriptive perspective analyzed data over a period of 6 years April 2015__April 2021 In Saudi hospital at Hajjah, Yemen. 226 thyroid operations for 207 patients ,135 patients diagnosis as Solitary thyroid nodule and 72 patients as Multi nodular goiter. the patients with a clinically as solitary thyroid nodule were included in the study group. Results: 135 cases of clinically detected STN,126 female and 9 male patients, between 14_65 years age, median 41 years and mean 39.76 years, (94 , 41)patients respectively Rt side thyroid effect more than Lt side, FNAC sensitivity, specificity and accuracy was (61% , 72% , 64%)respectively. Postoperative histopathology was reported 100(74%)patients as benign thyroid nodule and 35 patients(26%) as malignant thyroid nodule . Post operative transient hypocalcemia in 9 patients (7%), and temporary horsnese in 3 patients (2%). Conclusion: The incidence of malignancy in STN is high. Rapid growth by history and hard fixed nodule by examination and hypoechoic, micro calcification and cervical lymphadenopathy on USG frequently in malignant nodules. Male risk factor for thyroid cancer while age, number and size of nodules were not. FNAC more helpful for diagnosis if aspiration under USG guide and reading by experience histopathologest .Type of surgery depending on preoperative evaluation including history, examination, ultrasound, FNAC result, and intraoperative assessment of the nodule .Less complications of thyroid surgery by experience surgeon.
Study on the Third-Order Nonlinear Optical Properties of Cd2+ Ion Doped Zns/PVP Nanocomposite FilmsB. Suresh1, S. Ramachandran1 and G. Shanmugam2
Authors: Suresh B. , Ramachandran S. , SHANMUGAM G
Published: June 2021

Cd2+ ion doped ZnS/PVP nanocomposite films have been prepared using in-situ chemical method. XRD studies confirm the cubic structure of ZnS for all the films and the nanocrystallite size of ZnS is found to varying from 3.82 to 4.07 nm with Cd doping. The morphology of the films has been analyzed using SEM micrograph which shows the mono dispersion of ZnS nanoparticles in PVP matrix. The interaction between ZnS nanoparticles and PVP polymer matrix has been discussed using FTIR spectra. Optical absorption spectra of the films reveal the blue shift on the absorbance onset with the comparison of bulk ZnS and the estimated optical band gap energy decreases with increasing the concentration of Cd dopant. Photoluminescence spectra show a blue emission peak for all the films. The Z-scan results of three samples show a reverse saturation absorption process in open Z-scan experiment and self-focusing behavior in closed Z-scan experiment. Both ZnS/PVP and Cd2+ ion doped ZnS/PVP films exhibited the large optical nonlinearity and the value of nonlinear refractive index (n2), nonlinear absorption coefficient (β), third-order nonlinear optical susceptibility (χ(3)) and figure of merit (FOM) increase with Cd doping. The estimated n2, β, χ(3) and FOM values were found to be high for 6 mol% Cd doped ZnS/PVP nanocomposite film and they are about 1.771⋅10− 10 m2 W− 1, 4.148⋅10− 3 mW− 1, 1.603⋅10− 4 esu and 9.576⋅10− 6 esu m respectively. The experimental results clearly showed that the Cd2+ ion doped ZnS/PVP nanocomposite film is a worthy candidate for the future nonlinear optical device fabrication.
Increases in Use of Psychiatric Sick Leave During the COVID-19 Pandemic by Healthcare Workers in a Municipality of Argentina. Observed Versus Expected Cases in 2020 compared to Historical data.
Authors: Marconi Agustina M , Myers Ursula S , Retamar Alfredo M , Freddi Ivanna Jazmin , Zamora Rafael
Published: June 2021

Background: The severe respiratory syndrome caused by the novel coronavirus (SARS CoV 2) has caused world-wide pressure on the healthcare workers attempting to treat millions of individuals ill with COVID-19, in addition to their regular duties. Aims: examine the use of psychiatric leave by Argentinian healthcare workers during the COVID-19 pandemic; explore differences by gender. Methods: analysis of “excess of psychiatric sick leave” in health workers at a municipal level for Buenos Aires, January- October 2020. We used historical cases of psychiatric sick leave (2015-2019) and those requested in 2020. The differences between gender were determined using difference in proportions among groups. Results: The excess of psychiatric sick leave in 2020 compared to historical data was 161.90%. The difference in proportion per sex showed a significant 59.34% towards female. Conclusions: healthcare workers in the Argentinian municipality of Vicente Lopez used significantly higher number of psychiatric sick leaves during pandemic. The higher rates of psychiatric sick leave used by female replicate findings of higher rates of psychological symptoms in female healthcare workers.
Integrative Analysis of lncRNA-miRNA-mRNA Regulatory Network Reveals Candidate lncRNAs Responsible for Meat Quality in Goats
Authors: He Changsheng , Wang Yong , Zhu Jiangjiang , Xiong Yan , Li Yanyan , Chen Juan , Lin Yaqiu
Published: June 2021

Background: Goats are popular in China because of their superior meat quality, delicate flesh, and unique flavor. Long noncoding RNAs (lncRNAs) play important roles in transcriptional and post-transcriptional regulation of gene expression. However, the effects of lncRNAs on the meat quality of goat hasn’t been fully elucidated yet. Results: In this investigation, we performed RNA-Seq analysis of intramuscular and subcutaneous adipocytes from Jianzhou Daer goat before and after differentiation, including both intramuscular preadipocytes (IMPA) vs intramuscular adipocytes (IMA) and subcutaneous preadipocytes (SPA) vs subcutaneous adipocytes (SA). A total of 289.49 G clean reads and 12,519 lncRNAs were obtained from 20 samples. In total, 4,121 differentially expressed RNAs (388 miRNAs, 182 lncRNAs and 3,551 mRNAs) were identified by pairwise comparison. There were 135 differentially expressed lncRNAs specific to intramuscular adipocytes, 39 DELs specific to subcutaneous adipocytes, and 8 DELs common to both adipocytes in these 182 DELs. Some well-known and novel pathways associated with preadipocyte differentiation were identified: fat acid metabolism, TGF-beta signaling pathway and PI3K-Akt signaling pathway. We also identified hub miRNAS in both types of fat cells and visualized them in Cytoscape. Conclusions: Our analysis revealed the unique and common lncRNA-miRNA-mRNA networks of two kinds of adipocytes. Several lncRNAs that regulate goat meat quality were screened out, such as XR_001918647.1, XR_001917728.1, XR_001297263.2 and LNC_004191. Our study utilized RNA-seq analysis to predict the functions of lncRNA on goat meat quality. Furthermore, our findings of lncRNA-miRNA-mRNA network, may contribute to a better understanding of the molecular mechanisms underlying in goat meat quality and provide a theoretical basis for further goat molecular breeding.
Early Fresh Frozen Plasma Transfusion: Can It Improve the Outcomes of Patients With Sepsis?
Authors: Qin Xiaoyi , Zhang Wei , Zhu Xiaodan , Hu Xiang , Zhou Wei
Published: June 2021

Background: So far, no study has investigated the effects of plasma transfusion in septic patients, especially in terms of prognosis. Therefore, our purpose is to explore the association of early fresh frozen plasma (FFP) transfusion with the outcomes of septic patients.Methods: We performed a cohort study using data extracted from the Medical Information Mart for Intensive Care Ⅲ database (v1.4). External validation was obtained from the First Affiliated Hospital of Wenzhou Medical University, China. We adopted the Sepsis-3 criteria to extract patients with sepsis and septic shock. The occurrence of infusion during the first 3 days of intensive care unit stay was regarded as early FFP transfusion. The primary outcome was 28-day mortality. We assessed the association of early FFP transfusion with patient outcomes using cox regression analysis. Furthermore, we performed sensitivity analysis, subset analysis and external validation to verify the true strength of the results.Results: After adjusting for the covariates in 3 models respectively, the significantly higher risk of death in the FFP transfusion group at 28 days (e.g. Model 2: HR = 1.361, P = 0.018, 95% CI = 1.054–1.756) and 90 days (e.g. Model 2: HR = 1.368, P = 0.005, 95% CI = 1.099–1.704) remained distinctly. Contrarily, the mortality increased significantly with the increase of FFP transfusion volume. The outcomes of septic patients with low coagulation after early FFP transfusion were not significantly improved. Similar results can also be found in subset analysis of septic shock cohort. The results of external validation exhibited good consistency.Conclusions: Our study provides new understanding of the rationale and effectiveness of FFP transfusion for septic patients. After recognizing the evidences of risk-benefit and cost-benefit, it is important to reduce the inappropriate use of FFP and avoid unnecessary adverse transfusion reactions.