bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure S4 from Oncoprotein HBXIP Modulates Abnormal Lipid Metabolism and Growth of Breast Cancer Cells by Activating the LXRs/SREBP-1c/FAS Signaling Cascade
Authors: Zhao Yu , Li Hang , Zhang Yingyi , Li Leilei , Fang Runping , Li Yinghui , Liu Qian , Zhang Weiying , Qiu Liyan , Liu Fabao , Zhang Xiaodong , Ye Lihong
Published: April 2023

HBXIP directly binds to LXRs/RXRα to activate SREBP-1c promoter.
Supplementary Methods from Long Noncoding RNA GAPLINC Regulates CD44-Dependent Cell Invasiveness and Associates with Poor Prognosis of Gastric Cancer
Authors: Hu Ye , Wang Jilin , Qian Jin , Kong Xuan , Tang Jieting , Wang Yingchao , Chen Haoyan , Hong Jie , Zou Weiping , Chen Yingxuan , Xu Jie , Fang Jing-Yuan
Published: April 2023

Supplementary Methods. Description of additional methods and procedures used in the study.
Supplemental Figure S1 from Zfx Facilitates Tumorigenesis Caused by Activation of the Hedgehog Pathway
Authors: Palmer Colin J. , Galan-Caridad Jose M. , Weisberg Stuart P. , Lei Liang , Esquilin Jose M. , Croft Gist F. , Wainwright Brandon , Canoll Peter , Owens David M. , Reizis Boris
Published: April 2023

Topical tamoxifen treatment initiates formation of Sox9+ BCC in the skin.
Supplementary Figure 6 from CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus
Authors: Russell Mike R. , Penikis Annalise , Oldridge Derek A. , Alvarez-Dominguez Juan R. , McDaniel Lee , Diamond Maura , Padovan Olivia , Raman Pichai , Li Yimei , Wei Jun S. , Zhang Shile , Gnanchandran Janahan , Seeger Robert , Asgharzadeh Shahab , Khan Javed , Diskin Sharon J. , Maris John M. , Cole Kristina A.
Published: April 2023

Additional cell lines showing increased neuroblastoma cell growth following CASC15-S depletion.
Supplementary Figure 1 from CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus
Authors: Russell Mike R. , Penikis Annalise , Oldridge Derek A. , Alvarez-Dominguez Juan R. , McDaniel Lee , Diamond Maura , Padovan Olivia , Raman Pichai , Li Yimei , Wei Jun S. , Zhang Shile , Gnanchandran Janahan , Seeger Robert , Asgharzadeh Shahab , Khan Javed , Diskin Sharon J. , Maris John M. , Cole Kristina A.
Published: April 2023

Evidence supporting multiple lncRNA transcript isoforms mapping to chromosome 6p22.3.
Supplementary Figure and Table Legends from Adaptive Responses to Dasatinib-Treated Lung Squamous Cell Cancer Cells Harboring DDR2 Mutations
Authors: Bai Yun , Kim Jae-Young , Watters January M. , Fang Bin , Kinose Fumi , Song Lanxi , Koomen John M. , Teer Jamie K. , Fisher Kate , Chen Yian Ann , Rix Uwe , Haura Eric B.
Published: April 2023

Supplementary Figure and Table Legends. Legend for Supplementary Figures S1-S5 and Supplementary Tables S1-S5.
Supplementary Table 3 from PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin Neoplasia
Authors: McElwee John L. , Mohanan Sunish , Horibata Sachi , Sams Kelly L. , Anguish Lynne J. , McLean Dalton , Cvitaš Iva , Wakshlag Joseph J. , Coonrod Scott A.
Published: April 2023

Supplementary Table 3: Primers for human quantitative RT-PCR (SYBR)
Supplementary Data: Figures and Tables Legend from PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin Neoplasia
Authors: McElwee John L. , Mohanan Sunish , Horibata Sachi , Sams Kelly L. , Anguish Lynne J. , McLean Dalton , Cvitaš Iva , Wakshlag Joseph J. , Coonrod Scott A.
Published: April 2023

Supplementary Data: Figures and Tables Legend
Supplementary Figure Legends from Interleukin-6 Stimulates Defective Angiogenesis
Authors: Gopinathan Ganga , Milagre Carla , Pearce Oliver M.T. , Reynolds Louise E. , Hodivala-Dilke Kairbaan , Leinster David A. , Zhong Haihong , Hollingsworth Robert E. , Thompson Richard , Whiteford James R. , Balkwill Frances
Published: April 2023

Legend for Supplementary Figures S1-S7.
Supplementary Figure 4 from Pharmacological Inhibition of β3 Integrin Reduces the Inflammatory Toxicities Caused by Oncolytic Adenovirus without Compromising Anticancer Activity
Authors: Browne Ashley , Tookman Laura A. , Ingemarsdotter Carin K. , Bouwman Russell D. , Pirlo Katrina , Wang Yaohe , McNeish Iain A. , Lockley Michelle
Published: April 2023

Hexon immunohistochemistry in spleens of WT and b3-/- female mice 3hrs post IP injection with dl922-947 (10^10 particles). Hexon expression was scored by a pathologist who was blind to the experimental groups. (n = 6 mice per genotype)
Supplemental figures 1-5 from Neuroblastoma Arginase Activity Creates an Immunosuppressive Microenvironment That Impairs Autologous and Engineered Immunity
Authors: Mussai Francis , Egan Sharon , Hunter Stuart , Webber Hannah , Fisher Jonathan , Wheat Rachel , McConville Carmel , Sbirkov Yordan , Wheeler Kate , Bendle Gavin , Petrie Kevin , Anderson John , Chesler Louis , De Santo Carmela
Published: April 2023

Supplemental figures 1-5. Supplementary Figure 1: Arginase II is the principal arginase isoform in neuroblastoma Supplementary Figure 2: Arginase II expression by neuroblastoma tumours creates a suppressive microenvironment Supplementary Figure 3: Neuroblastoma alters myeloid cell frequency in a murine model Supplementary Figure 4: Neuroblastoma arginase inactivates CD14+ cells and CAR T cells Supplementary Figure 5: Arginase 2 and CD14 expression are associated with a worse overall survival.
Supplementary Table S1 from Nitrostyrene Derivatives Act as RXRα Ligands to Inhibit TNFα Activation of NF-κB
Authors: Zeng Zhiping , Sun Zhe , Huang Mingfeng , Zhang Weidong , Liu Jie , Chen Liqun , Chen Fan , Zhou Yuqi , Lin Jiacheng , Huang Fengyu , Xu Lin , Zhuang Zixing , Guo Shangjie , Alitongbieke Gulimiran , Xie Guobin , Xu Yang , Lin Bingzhen , Cao Xihua , Su Ying , Zhang Xiao-kun , Zhou Hu
Published: April 2023

Supplementary Table S1. Z serial compounds.
Supp tables 1 and 2 from Neuroblastoma Arginase Activity Creates an Immunosuppressive Microenvironment That Impairs Autologous and Engineered Immunity
Authors: Mussai Francis , Egan Sharon , Hunter Stuart , Webber Hannah , Fisher Jonathan , Wheat Rachel , McConville Carmel , Sbirkov Yordan , Wheeler Kate , Bendle Gavin , Petrie Kevin , Anderson John , Chesler Louis , De Santo Carmela
Published: April 2023

Supp tables 1 and 2. Supplementary Table 1 Table of patient clinical characteristics for patient derived samples Supplementary Table 2 PCR Primer sequences
Supplementary Figures S1-S6 from Nitrostyrene Derivatives Act as RXRα Ligands to Inhibit TNFα Activation of NF-κB
Authors: Zeng Zhiping , Sun Zhe , Huang Mingfeng , Zhang Weidong , Liu Jie , Chen Liqun , Chen Fan , Zhou Yuqi , Lin Jiacheng , Huang Fengyu , Xu Lin , Zhuang Zixing , Guo Shangjie , Alitongbieke Gulimiran , Xie Guobin , Xu Yang , Lin Bingzhen , Cao Xihua , Su Ying , Zhang Xiao-kun , Zhou Hu
Published: April 2023

Supplementary Figures S1-S6. Z compounds selectively activate Gal4-DBD-RXRα-LBD transcriptional activity in a dose-dependent manner (S1); Nitro group is required for Z-10 and Z-12 binding to RXRα-LBD (S2); Z-10 and Z-12 bind RXRα in a unique manner (S3); Z-10 and Z-12 inhibit TNFα activation of NFκB in RXRα/tRXRα dependent manner (S4); Z-10 and Z-12 inhibit tRXRα-mediated TNFα activation of NFκB (S5); Z compounds and TNFα synergistically induce cancer cell apoptosis in a tRXRα-dependent manner (S6).
Supplementary Figures S1-S11 from TLR5 Ligand–Secreting T Cells Reshape the Tumor Microenvironment and Enhance Antitumor Activity
Authors: Geng Degui , Kaczanowska Sabina , Tsai Alexander , Younger Kenisha , Ochoa Augusto , Rapoport Aaron P. , Ostrand-Rosenberg Sue , Davila Eduardo
Published: April 2023

Supplementary Figures S1-S11. TLR5L enhances the proliferation of human CD4 T cells (S1); Transduced human T cells coexpressing DMF5 and the TLR5L show significantly increased proliferation, cytokine production, and cytolytic activity than T cells expressing MART-1 TCR alone (S2); Human TLR5 protein expression in Malme-3M and C32 cell lines, and melanoma biopsy specimens (S3); TLR5 on Malme-3M cells enhances the cytokine and chemokine transcript levels (S4); MHC class I and II expression on Malme-3M cells stimulated with supernatants from various experimental conditions (S5); TLR5 engagement on C32 cells enhances the recruitment of various leukocyte subpopulations (S6); Chemokine receptor expression on non-transduced and transduced T cells stimulated with or without TLR5L (S7); Effects of TLR5L on the production of cytokines and chemokines on B16 and/or pmel CD8 T cells (S8); MHC class I and II expression on B16 cells stimulated with supernatants from various experimental conditions (S9); TLR5L stimulation does effect MDSC suppressive capacity or phenotype in vitro (S10); Diagram depicting how intratumoral delivery of TLR5L by CD8 T cells augments anti-tumor responses (S11).
Supplementary Figure Legend from Nitrostyrene Derivatives Act as RXRα Ligands to Inhibit TNFα Activation of NF-κB
Authors: Zeng Zhiping , Sun Zhe , Huang Mingfeng , Zhang Weidong , Liu Jie , Chen Liqun , Chen Fan , Zhou Yuqi , Lin Jiacheng , Huang Fengyu , Xu Lin , Zhuang Zixing , Guo Shangjie , Alitongbieke Gulimiran , Xie Guobin , Xu Yang , Lin Bingzhen , Cao Xihua , Su Ying , Zhang Xiao-kun , Zhou Hu
Published: April 2023

Supplementary Figure Legend. Legends for Supplementary Figures S1-S6.
Supplementary Figure Legend from TLR5 Ligand–Secreting T Cells Reshape the Tumor Microenvironment and Enhance Antitumor Activity
Authors: Geng Degui , Kaczanowska Sabina , Tsai Alexander , Younger Kenisha , Ochoa Augusto , Rapoport Aaron P. , Ostrand-Rosenberg Sue , Davila Eduardo
Published: April 2023

Supplementary Figure Legend. Legends for Supplementary Figures S1-S11.
Supplementary Figures S1-S10 from Cytomegalovirus Immediate-Early Proteins Promote Stemness Properties in Glioblastoma
Authors: Soroceanu Liliana , Matlaf Lisa , Khan Sabeena , Akhavan Armin , Singer Eric , Bezrookove Vladimir , Decker Stacy , Ghanny Saleena , Hadaczek Piotr , Bengtsson Henrik , Ohlfest John , Luciani-Torres Maria-Gloria , Harkins Lualhati , Perry Arie , Guo Hong , Soteropoulos Patricia , Cobbs Charles S.
Published: April 2023

IE1 Sequence Alignment in Several Primary GBM Tissues (S1); HCMV IE is enriched in the SSEA1+ fraction of primary GBM cells and co-localizes with stemness markers in situ (S2); IE siRNA Optimization (S3); HCMV transcripts are enriched in the GSC fraction (S4); HCMV IE modulates Sox2 expression in GBM via miR145 (S5); IE1 overexpression induces Sox2 via miRNA145 inhibition in GSCs (S6); IE attenuation induces a mesenchymal and pro-inflammatory phenotype in HCMV-positive GSC (S7); Immunohistochemical analyses of IE1+/- mouse gliomas (S8); GSC lines used in this study are tumorigenic in vivo (S9); CR208, an IE1 deficient HCMV does not promote GBM stemness to the same extent as Towne parental strain (S10).
Supplemental Table and Figure Legends from A Novel Cinnamon-Related Natural Product with Pim-1 Inhibitory Activity Inhibits Leukemia and Skin Cancer
Authors: Kim Jong-Eun , Son Joe Eun , Jeong Hyein , Kim Dong Joon , Seo Sang Gwon , Lee Eunjung , Lim Tae Gyu , Kim Jong Rhan , Kimbung Yengo Raymond , Chen Hanyong , Bode Ann M. , Lee Ki Won , Dong Zigang
Published: April 2023

Supplemental Table and Figure Legends. Legend for Supplemental Tables S1-S2 and Supplemental Figure S1.
Supplementary Figures S1-S5 from Lin28B/Let-7 Regulates Expression of Oct4 and Sox2 and Reprograms Oral Squamous Cell Carcinoma Cells to a Stem-like State
Authors: Chien Chian-Shiu , Wang Mong-Lien , Chu Pen-Yuan , Chang Yuh-Lih , Liu Wei-Hsiu , Yu Cheng-Chia , Lan Yuan-Tzu , Huang Pin-I. , Lee Yi-Yen , Chen Yi-Wei , Lo Wen-Liang , Chiou Shih-Hwa
Published: April 2023

Supplementary Figures S1-S5. Lin28B regulated the stemness expression and tumor initiation (S1); Lin28B/Let7 axis regulated the stemness signature expression (S2); Let7 directly targets HMGA2 3'UTR in OSCC cells (S3); HMGA2 induces Sox2 expression through direct promoter binding (S4); Delivery of synthetic hsa-Let-7 blocked the tumor growth of OSCC-CSC cells in vivo (S5).
Supplementary Information from Metastatic Heterogeneity of Breast Cancer Cells Is Associated with Expression of a Heterogeneous TGFβ-Activating miR424–503 Gene Cluster
Authors: Li Yun , Li Wei , Ying Zhe , Tian Han , Zhu Xun , Li Jun , Li Mengfeng
Published: April 2023

Supplementary Information. Supplementary Information including Supplementary Materials and Methods, and Supplementary Figure Legends.
Supplementary Figure Legends from Lin28B/Let-7 Regulates Expression of Oct4 and Sox2 and Reprograms Oral Squamous Cell Carcinoma Cells to a Stem-like State
Authors: Chien Chian-Shiu , Wang Mong-Lien , Chu Pen-Yuan , Chang Yuh-Lih , Liu Wei-Hsiu , Yu Cheng-Chia , Lan Yuan-Tzu , Huang Pin-I. , Lee Yi-Yen , Chen Yi-Wei , Lo Wen-Liang , Chiou Shih-Hwa
Published: April 2023

Supplementary Figure Legends. Legend for Supplementary Figures S1-S5.
Supplemental Table S1 from Metastatic Heterogeneity of Breast Cancer Cells Is Associated with Expression of a Heterogeneous TGFβ-Activating miR424–503 Gene Cluster
Authors: Li Yun , Li Wei , Ying Zhe , Tian Han , Zhu Xun , Li Jun , Li Mengfeng
Published: April 2023

Supplemental Table S1. Clinicopathologic characteristics of breast cancer patients.
Supplemental Figure S7 from Metastatic Heterogeneity of Breast Cancer Cells Is Associated with Expression of a Heterogeneous TGFβ-Activating miR424–503 Gene Cluster
Authors: Li Yun , Li Wei , Ying Zhe , Tian Han , Zhu Xun , Li Jun , Li Mengfeng
Published: April 2023

Supplemental Figure S7. Quantitative PCR (qPCR) analysis of miR-424 and miR-503 expression in p-Smad3 tissues and qPCR analysis of Smad7 and Smurf2 expression in TβRE-GFP cells.
Supplementary Methods from Tracking and Functional Characterization of Epithelial–Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis
Authors: Ruscetti Marcus , Quach Bill , Dadashian Eman L. , Mulholland David J. , Wu Hong
Published: April 2023

Supplementary Methods. Description of additional methods and procedures used in the study.
Supplemental Figure S4 from Metastatic Heterogeneity of Breast Cancer Cells Is Associated with Expression of a Heterogeneous TGFβ-Activating miR424–503 Gene Cluster
Authors: Li Yun , Li Wei , Ying Zhe , Tian Han , Zhu Xun , Li Jun , Li Mengfeng
Published: April 2023

Supplemental Figure S4. miR-424-503 cluster promotes metastasis of breast cancer cells in spontaneous metastasis assays.
Supplementary Figure S4 from Tracking and Functional Characterization of Epithelial–Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis
Authors: Ruscetti Marcus , Quach Bill , Dadashian Eman L. , Mulholland David J. , Wu Hong
Published: April 2023

Supplementary Figure S4. Characterization of CTCs and iCTCs by FACS analysis.
Supplemental Figure S2 from Metastatic Heterogeneity of Breast Cancer Cells Is Associated with Expression of a Heterogeneous TGFβ-Activating miR424–503 Gene Cluster
Authors: Li Yun , Li Wei , Ying Zhe , Tian Han , Zhu Xun , Li Jun , Li Mengfeng
Published: April 2023

Supplemental Figure S2. Expression of miR-424/miR-503 in cell lines stably expressing miR-424/miR-503 or miR-424-503 cluster.
Supplementary Figure S2 from Tracking and Functional Characterization of Epithelial–Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis
Authors: Ruscetti Marcus , Quach Bill , Dadashian Eman L. , Mulholland David J. , Wu Hong
Published: April 2023

Supplementary Figure S2. The anterior portion of the urethra and proximal region of the anterior lobes regenerate tumors containing all three prostate epithelial lineages.
Supplementary Figure S1 from Tracking and Functional Characterization of Epithelial–Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis
Authors: Ruscetti Marcus , Quach Bill , Dadashian Eman L. , Mulholland David J. , Wu Hong
Published: April 2023

Supplementary Figure S1. EMT-like and mesenchymal tumor cell populations from CPKV mice are derived from the Pten-/- epithelium
Supplemental Table 1 from KRAS Genomic Status Predicts the Sensitivity of Ovarian Cancer Cells to Decitabine
Authors: Stewart Michelle L. , Tamayo Pablo , Wilson Andrew J. , Wang Stephanie , Chang Yun Min , Kim Jong W. , Khabele Dineo , Shamji Alykhan F. , Schreiber Stuart L.
Published: April 2023

The differential mutual information score (Ic, methods) is used in this table to correlate gene mutations and copy number variations with activity of decitabine in solid tumor cell lines.
Supplementary Tables S1-S3 from G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation
Authors: Agarwal Saurabh , Lakoma Anna , Chen Zaowen , Hicks John , Metelitsa Leonid S. , Kim Eugene S. , Shohet Jason M.
Published: April 2023

Supplementary Tables S1-S3. IC50 for different drug combinations (S1); Gene Ontology analysis for genes upregulated in CD114+ cells (S2); Primers used in the study (S3).
Supplementary Materials, Tables S1-3, Figures S1-3 from Quantifying the Landscape for Development and Cancer from a Core Cancer Stem Cell Circuit
Authors: Li Chunhe , Wang Jin
Published: April 2023

Supplementary Materials, Tables S1-3, Figures S1-3. Table S1. Names of 6 genes in the cancer and developmental network and the corresponding function description. Table S2. Activation link names in sensitivity analysis and the corresponding regulations they represent. The order numbers for causal and target genes are shown, which are corresponding to the gene name in Table S1. Table S3. Repression link names in the sensitivity analysis and the corresponding regulations they represent. The order numbers for causal and target genes are shown, which are corresponding to the gene name in Table S1. Figure S1. Transition action for the dominant path and the mean first passage time between CSC attractor and cancer attractor. Figure S2. Global sensitivity analysis for regulation strengths (7 activation links and 9 repression links) in terms of transition action S (A, B) and potential barriers (C, D). Figure S3. A flowchart for methods employed. GRN represents the gene regulatory network.
Supplementary Figure S6 from AKT1 and MYC Induce Distinctive Metabolic Fingerprints in Human Prostate Cancer
Authors: Priolo Carmen , Pyne Saumyadipta , Rose Joshua , Regan Erzsébet Ravasz , Zadra Giorgia , Photopoulos Cornelia , Cacciatore Stefano , Schultz Denise , Scaglia Natalia , McDunn Jonathan , De Marzo Angelo M. , Loda Massimo
Published: April 2023

Segregation of phosphoAKT1-high and MYC-high prostate tumors by genomics and protein expression. (A) SNP arrays (Affymetrix 250K Sty I array) were performed on 59 prostate tumors and 6 normal tissues. The heat map showing inferred copy number profile was generated with DChip version 2010.01. Densitometric values of phosphoAKT1 or MYC protein (relative to β-actin) for each sample are depicted in the top orange/green heat map. The black bars in the color scales represent the cut-off for low and high protein values. (B) Venn diagram showing the intersections between genomic and protein expression data. Twelve and 11 tumors harbored 10q23.31 loss (PTEN locus, orange circle in (A), chromosome 10) and 8q24.3 gain (MYC locus, green circle in (A), chromosome 8), respectively, representing 26% (7/27) of phosphoAKT1-high and 13% (2/15) of MYC-high tumors.
Supplementary Figure S5 from AKT1 and MYC Induce Distinctive Metabolic Fingerprints in Human Prostate Cancer
Authors: Priolo Carmen , Pyne Saumyadipta , Rose Joshua , Regan Erzsébet Ravasz , Zadra Giorgia , Photopoulos Cornelia , Cacciatore Stefano , Schultz Denise , Scaglia Natalia , McDunn Jonathan , De Marzo Angelo M. , Loda Massimo
Published: April 2023

mRNA expression of metabolic genes in RWPE-AKT1 or RWPE-MYC vs. RWPE-EV cells (A), or human prostate tumors relative to a normal prostate tissue pool (B). (C) FASN levels in RWPE-AKT1, RWPE-MYC and control (RWPE-EV) cells, and tumors vs. normal prostate tissues are shown. Association of high (dark grey)/low (white) GLUT-1 with phosphoAKT1 expression (p<0.05) (D) Diagram depicting all analyzed enzyme transcripts within the related metabolic pathways.
Supplementary Figure 3 from Preclinical Characterization of Novel Chordoma Cell Systems and Their Targeting by Pharmocological Inhibitors of the CDK4/6 Cell-Cycle Pathway
Authors: von Witzleben Adrian , Goerttler Lukas T. , Marienfeld Ralf , Barth Holger , Lechel André , Mellert Kevin , Böhm Michael , Kornmann Marko , Mayer-Steinacker Regine , von Baer Alexandra , Schultheiss Markus , Flanagan Adrienne M. , Möller Peter , Brüderlein Silke , Barth Thomas F.E.
Published: April 2023

Western blot analyses of 8 chordoma cell lines showing expression of brachyury at 47 kDa.
Supplementary Figure S4 from AKT1 and MYC Induce Distinctive Metabolic Fingerprints in Human Prostate Cancer
Authors: Priolo Carmen , Pyne Saumyadipta , Rose Joshua , Regan Erzsébet Ravasz , Zadra Giorgia , Photopoulos Cornelia , Cacciatore Stefano , Schultz Denise , Scaglia Natalia , McDunn Jonathan , De Marzo Angelo M. , Loda Massimo
Published: April 2023

Concentration of creatine (A, B) and 2-Aminoadipate (C, D) in human prostate tissue samples. The concentration values by untargeted metabolomics (normalized values) are shown in (A) and (C). The concentration values obtained by absolute quantification (µg/g tissue) are shown in (B) and (D).
Supplemental Figure S3 from Endothelial ALK1 Is a Therapeutic Target to Block Metastatic Dissemination of Breast Cancer
Authors: Cunha Sara I. , Bocci Matteo , Lövrot John , Eleftheriou Nikolas , Roswall Pernilla , Cordero Eugenia , Lindström Linda , Bartoschek Michael , Haller B. Kristian , Pearsall R. Scott , Mulivor Aaron W. , Kumar Ravindra , Larsson Christer , Bergh Jonas , Pietras Kristian
Published: April 2023

Relating ACVRL1 to prototypical endothelial gene expression makes the association with risk of distant disease coherent across treatment groups.
Supplementary Figure 1 from MyD88-Dependent Signaling Decreases the Antitumor Efficacy of Epidermal Growth Factor Receptor Inhibition in Head and Neck Cancer Cells
Authors: Koch Adam T. , Love-Homan Laurie , Espinosa-Cotton Madelyn , Stanam Aditya , Simons Andrean L.
Published: April 2023

Knockdown of TRIF does not reduce erlotinib-induced IL-6.
Figure S3 from Fas Ligand Deficiency Impairs Tumor Immunity by Promoting an Accumulation of Monocytic Myeloid-Derived Suppressor Cells
Authors: Peyvandi Sanam , Buart Stéphanie , Samah Boubekeur , Vétizou Marie , Zhang Yanyan , Durrieu Ludovic , Polrot Mélanie , Chouaib Salem , Benihoud Karim , Louache Fawzia , Karray Saoussen
Published: April 2023

Figure S3. Increased M-MDSC subset in tumor infiltrates from Fasl-/- mice.
Figure S1 from Fas Ligand Deficiency Impairs Tumor Immunity by Promoting an Accumulation of Monocytic Myeloid-Derived Suppressor Cells
Authors: Peyvandi Sanam , Buart Stéphanie , Samah Boubekeur , Vétizou Marie , Zhang Yanyan , Durrieu Ludovic , Polrot Mélanie , Chouaib Salem , Benihoud Karim , Louache Fawzia , Karray Saoussen
Published: April 2023

Figure S1. Myeloid cell distribution in naïve and LLC-bearing mice.
Supplementary Table S3 from Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival
Authors: Schliekelman Mark J. , Taguchi Ayumu , Zhu Jun , Dai Xudong , Rodriguez Jaime , Celiktas Muge , Zhang Qing , Chin Alice , Wong Chee-Hong , Wang Hong , McFerrin Lisa , Selamat Suhaida A. , Yang Chenchen , Kroh Evan M. , Garg Kavita S. , Behrens Carmen , Gazdar Adi F. , Laird-Offringa Ite A. , Tewari Muneesh , Wistuba Ignacio I. , Thiery Jean P. , Hanash Samir M.
Published: April 2023

Supplementary Table S3. Gene and protein expression of epithelial and mesenchymal markers.
Supplemental Table S2 from PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways
Authors: Kaistha Brajesh P. , Lorenz Holger , Schmidt Harald , Sipos Bence , Pawlak Michael , Gierke Berthold , Kreider Ramona , Lankat-Buttgereit Brigitte , Sauer Melanie , Fiedler Lisa , Krattenmacher Anja , Geisel Bettina , Kraus Johann M. , Frese Kristopher K. , Kelkenberg Sabine , Giese Nathalia A. , Kestler Hans A. , Gress Thomas M. , Buchholz Malte
Published: April 2023

List of differentially expressed transcripts.
Supplementary Table S2 from Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival
Authors: Schliekelman Mark J. , Taguchi Ayumu , Zhu Jun , Dai Xudong , Rodriguez Jaime , Celiktas Muge , Zhang Qing , Chin Alice , Wong Chee-Hong , Wang Hong , McFerrin Lisa , Selamat Suhaida A. , Yang Chenchen , Kroh Evan M. , Garg Kavita S. , Behrens Carmen , Gazdar Adi F. , Laird-Offringa Ite A. , Tewari Muneesh , Wistuba Ignacio I. , Thiery Jean P. , Hanash Samir M.
Published: April 2023

Supplementary Table S2. Comparison of mRNAs, proteins, microRNAs, and DNA methylation in epithelial and mesenchymal cell lines and related gene ontology.
Supplemental Movie S5- TIRF assay from PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways
Authors: Kaistha Brajesh P. , Lorenz Holger , Schmidt Harald , Sipos Bence , Pawlak Michael , Gierke Berthold , Kreider Ramona , Lankat-Buttgereit Brigitte , Sauer Melanie , Fiedler Lisa , Krattenmacher Anja , Geisel Bettina , Kraus Johann M. , Frese Kristopher K. , Kelkenberg Sabine , Giese Nathalia A. , Kestler Hans A. , Gress Thomas M. , Buchholz Malte
Published: April 2023

S2-007 cells were transfected with Plac8-YFP and TIRF images of an individual cell recorded over a timeframe of 9 min.
Supplementary Figure S2 from Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival
Authors: Schliekelman Mark J. , Taguchi Ayumu , Zhu Jun , Dai Xudong , Rodriguez Jaime , Celiktas Muge , Zhang Qing , Chin Alice , Wong Chee-Hong , Wang Hong , McFerrin Lisa , Selamat Suhaida A. , Yang Chenchen , Kroh Evan M. , Garg Kavita S. , Behrens Carmen , Gazdar Adi F. , Laird-Offringa Ite A. , Tewari Muneesh , Wistuba Ignacio I. , Thiery Jean P. , Hanash Samir M.
Published: April 2023

Supplementary Figure S2. Molecular characterization of mesenchymal and epithelial cell lines.
Supplementary Figure S1 from Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival
Authors: Schliekelman Mark J. , Taguchi Ayumu , Zhu Jun , Dai Xudong , Rodriguez Jaime , Celiktas Muge , Zhang Qing , Chin Alice , Wong Chee-Hong , Wang Hong , McFerrin Lisa , Selamat Suhaida A. , Yang Chenchen , Kroh Evan M. , Garg Kavita S. , Behrens Carmen , Gazdar Adi F. , Laird-Offringa Ite A. , Tewari Muneesh , Wistuba Ignacio I. , Thiery Jean P. , Hanash Samir M.
Published: April 2023

Supplementary Figure S1. Background information for lung adenocarcinoma cell lines.
Supplemental Movie S2- Plac8-PrP-vesicle from PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways
Authors: Kaistha Brajesh P. , Lorenz Holger , Schmidt Harald , Sipos Bence , Pawlak Michael , Gierke Berthold , Kreider Ramona , Lankat-Buttgereit Brigitte , Sauer Melanie , Fiedler Lisa , Krattenmacher Anja , Geisel Bettina , Kraus Johann M. , Frese Kristopher K. , Kelkenberg Sabine , Giese Nathalia A. , Kestler Hans A. , Gress Thomas M. , Buchholz Malte
Published: April 2023

3D rendering of stacked images of a Plac8- and PrP-positive intracellular vesicle.
Supplemental Movie S1- Protease protection assay from PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways
Authors: Kaistha Brajesh P. , Lorenz Holger , Schmidt Harald , Sipos Bence , Pawlak Michael , Gierke Berthold , Kreider Ramona , Lankat-Buttgereit Brigitte , Sauer Melanie , Fiedler Lisa , Krattenmacher Anja , Geisel Bettina , Kraus Johann M. , Frese Kristopher K. , Kelkenberg Sabine , Giese Nathalia A. , Kestler Hans A. , Gress Thomas M. , Buchholz Malte
Published: April 2023

S2-007 cells were co-transfected with Plac8-CFP (left panels/green pseudocolor in overlay) and YFP (middle panels/red pseudocolor in overlay). At the 60 s time point, cells were treated with digitonin, and at the 400 s time point trypsin was added. Scale bars: 10 µm.
Supplementary Materials and methods, figure legends and tables from Long Noncoding RNA HULC Modulates Abnormal Lipid Metabolism in Hepatoma Cells through an miR-9–Mediated RXRA Signaling Pathway
Authors: Cui Ming , Xiao Zelin , Wang Yue , Zheng Minying , Song Tianqiang , Cai Xiaoli , Sun Baodi , Ye Lihong , Zhang Xiaodong
Published: April 2023

Supplementary Materials and methods, figure legends and tables. Supplementary Table 1. The Characteristics of HCC Patients Supplementary Table S2. List of primers used in this paper. Supplementary Table S3. List of siRNA and miRNA Supplementary Table S4. Clinical characteristics of liver cancer and normal tissue.
Supplemental Figure S5 from PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways
Authors: Kaistha Brajesh P. , Lorenz Holger , Schmidt Harald , Sipos Bence , Pawlak Michael , Gierke Berthold , Kreider Ramona , Lankat-Buttgereit Brigitte , Sauer Melanie , Fiedler Lisa , Krattenmacher Anja , Geisel Bettina , Kraus Johann M. , Frese Kristopher K. , Kelkenberg Sabine , Giese Nathalia A. , Kestler Hans A. , Gress Thomas M. , Buchholz Malte
Published: April 2023

Differentialy expressed transcripts.
Supplemental Figure S4 from PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways
Authors: Kaistha Brajesh P. , Lorenz Holger , Schmidt Harald , Sipos Bence , Pawlak Michael , Gierke Berthold , Kreider Ramona , Lankat-Buttgereit Brigitte , Sauer Melanie , Fiedler Lisa , Krattenmacher Anja , Geisel Bettina , Kraus Johann M. , Frese Kristopher K. , Kelkenberg Sabine , Giese Nathalia A. , Kestler Hans A. , Gress Thomas M. , Buchholz Malte
Published: April 2023

Plac8 knockdown does not affect Akt/ phospho-Akt and c-Myc levels.
Supplemental Figure S2 from PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways
Authors: Kaistha Brajesh P. , Lorenz Holger , Schmidt Harald , Sipos Bence , Pawlak Michael , Gierke Berthold , Kreider Ramona , Lankat-Buttgereit Brigitte , Sauer Melanie , Fiedler Lisa , Krattenmacher Anja , Geisel Bettina , Kraus Johann M. , Frese Kristopher K. , Kelkenberg Sabine , Giese Nathalia A. , Kestler Hans A. , Gress Thomas M. , Buchholz Malte
Published: April 2023

Plac8/PrP immunofluorescence.
Supplemental Figure S2 from SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex
Authors: Feng Yongmei , Pinkerton Anthony B. , Hulea Laura , Zhang Tongwu , Davies Michael A. , Grotegut Stefan , Cheli Yann , Yin Hongwei , Lau Eric , Kim Hyungsoo , De Surya K. , Barile Elisa , Pellecchia Maurizio , Bosenberg Marcus , Li Jian-Liang , James Brian , Hassig Christian A. , Brown Kevin M. , Topisirovic Ivan , Ronai Ze'ev A.
Published: April 2023

SBI-756 disrupts eIF4F complex in parent and BRAFi-resistant melanoma.
Figure S1 from Cell Cycle–Dependent Mechanisms Underlie Vincristine-Induced Death of Primary Acute Lymphoblastic Leukemia Cells
Authors: Kothari Anisha , Hittelman Walter N. , Chambers Timothy C.
Published: April 2023

Supplementary Figure 1
Supplementary Figure S7 from Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells
Authors: Lerner Robin G. , Grossauer Stefan , Kadkhodaei Banafsheh , Meyers Ian , Sidorov Maxim , Koeck Katharina , Hashizume Rintaro , Ozawa Tomoko , Phillips Joanna J. , Berger Mitchel S. , Nicolaides Theodore , James C. David , Petritsch Claudia K.
Published: April 2023

Effect of combined inhibition of BRAFV600E and PLK1 on CD133+ cells.
Supplementary Figure S2 from Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity
Authors: Shanker Anil , Pellom Samuel T. , Dudimah Duafalia F. , Thounaojam Menaka C. , de Kluyver Rachel L. , Brooks Alan D. , Yagita Hideo , McVicar Daniel W. , Murphy William J. , Longo Dan L. , Sayers Thomas J.
Published: April 2023

Lasting immunosuppressive effect on lung metastases following the suppressive regimen of bortezomib.
Supplementary Figure S3 from Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells
Authors: Lerner Robin G. , Grossauer Stefan , Kadkhodaei Banafsheh , Meyers Ian , Sidorov Maxim , Koeck Katharina , Hashizume Rintaro , Ozawa Tomoko , Phillips Joanna J. , Berger Mitchel S. , Nicolaides Theodore , James C. David , Petritsch Claudia K.
Published: April 2023

Polarization, asymmetric divisions, PLK1 activity and G2/M phase in CD133+ GBM cells.
Supplementary Table S3 from CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer
Authors: Yoshida Taku , Kim Jee Hyun , Carver Kristopher , Su Ying , Weremowicz Stanislawa , Mulvey Laura , Yamamoto Shoji , Brennan Cameron , Mei Shenglin , Long Henry , Yao Jun , Polyak Kornelia
Published: April 2023

Supplementary Table S3. Copy number gain and expression of selected kinases in breast cancer cell lines based on qPCR.
Supplementary Figures from CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer
Authors: Yoshida Taku , Kim Jee Hyun , Carver Kristopher , Su Ying , Weremowicz Stanislawa , Mulvey Laura , Yamamoto Shoji , Brennan Cameron , Mei Shenglin , Long Henry , Yao Jun , Polyak Kornelia
Published: April 2023

Supplementary Figures S1-S4: Supplementary Figure S1. CLK2 copy number and gene expression in breast cancer. Supplementary Figure S2. Validation of shRNA screen results for CLK2. Supplementary Figure S3. EMT-related changes following downregulation of CLK2. Supplementary Figure S4. Identification of breast tumor subtype-specific splice variants regulated by CLK2.
Supplementary Tables S1-S2 from SND1 Acts Downstream of TGFβ1 and Upstream of Smurf1 to Promote Breast Cancer Metastasis
Authors: Yu Lin , Liu Xin , Cui Kang , Di Yanbo , Xin Lingbiao , Sun Xiaoming , Zhang Wei , Yang Xi , Wei Minxin , Yao Zhi , Yang Jie
Published: April 2023

Supplementary Tables S1-S2. Primers used in the manuscript (S1); Expression of SND1 in Human Breast Tissues (S2).
Supplementary Figure S1 from SND1 Acts Downstream of TGFβ1 and Upstream of Smurf1 to Promote Breast Cancer Metastasis
Authors: Yu Lin , Liu Xin , Cui Kang , Di Yanbo , Xin Lingbiao , Sun Xiaoming , Zhang Wei , Yang Xi , Wei Minxin , Yao Zhi , Yang Jie
Published: April 2023

Supplementary Figure S1. Gain-of-function of SND1 in stable SND1-knockdown cell line could reverse the phenotype induced by lacking of SND1.
Figure S1 from Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response
Authors: Bartkowiak Kai , Kwiatkowski Marcel , Buck Friedrich , Gorges Tobias M. , Nilse Lars , Assmann Volker , Andreas Antje , Müller Volkmar , Wikman Harriet , Riethdorf Sabine , Schlüter Hartmut , Pantel Klaus
Published: April 2023

Immunofluorescence and western blot analyses; Grp78va in DTC
Supplemental Figure S2 from Akt–Girdin Signaling in Cancer-Associated Fibroblasts Contributes to Tumor Progression
Authors: Yamamura Yumiko , Asai Naoya , Enomoto Atsushi , Kato Takuya , Mii Shinji , Kondo Yuji , Ushida Kaori , Niimi Kaoru , Tsunoda Nobuyuki , Nagino Masato , Ichihara Shu , Furukawa Koichi , Maeda Kengo , Murohara Toyoaki , Takahashi Masahide
Published: April 2023

The arbitrary grading scale was developed to quantitate the phosphorylation of Girdin in CAF in tissue sections.
Supplementary Figure S4 from Exploring the Biomechanical Properties of Brain Malignancies and Their Pathologic Determinants In Vivo with Magnetic Resonance Elastography
Authors: Jamin Yann , Boult Jessica K.R. , Li Jin , Popov Sergey , Garteiser Philippe , Ulloa Jose L. , Cummings Craig , Box Gary , Eccles Suzanne A. , Jones Chris , Waterton John C. , Bamber Jeffrey C. , Sinkus Ralph , Robinson Simon P.
Published: April 2023

Supplementary Figure S4. Histological evaluation of the vascular phenotype of U-87 MG, RG2 and MDA-MB-231 tumors.
Supplemental Figures from A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors
Authors: Zhong Haihong , Davis April , Ouzounova Maria , Carrasco Rosa A. , Chen Cui , Breen Shannon , Chang Yong S. , Huang Jiaqi , Liu Zheng , Yao Yihong , Hurt Elaine , Moisan Jacques , Fung Michael , Tice David A. , Clouthier Shawn G. , Xiao Zhan , Wicha Max S. , Korkaya Hasan , Hollingsworth Robert E.
Published: April 2023

Supplemental Figures
Supplementary Figure S4 from Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin–GUCY2C Paracrine Signaling Axis
Authors: Lin Jieru E. , Colon-Gonzalez Francheska , Blomain Erik , Kim Gilbert W. , Aing Amanda , Stoecker Brian , Rock Justin , Snook Adam E. , Zhan Tingting , Hyslop Terry M. , Tomczak Michal , Blumberg Richard S. , Waldman Scott A.
Published: April 2023

Daily calorie intake, body weights, and guanylin expression in wild type and obesity-resistant (HF-R) C57BL/6 mice on lean or high fat (HF) diets.
Supplementary Data from Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane Fluidity
Authors: Zhao Weina , Prijic Sara , Urban Bettina C. , Tisza Michael J. , Zuo Yan , Li Lin , Tan Zhi , Chen Xiaoling , Mani Sendurai A. , Chang Jeffrey T.
Published: April 2023

Supplementary Materials and Methods Supplementary Figure Legends Supplementary Table Legends
Supplementary Methods and References from Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b–Mediated Malignant Progression
Authors: Picon-Ruiz Manuel , Pan Chendong , Drews-Elger Katherine , Jang Kibeom , Besser Alexandra H. , Zhao Dekuang , Morata-Tarifa Cynthia , Kim Minsoon , Ince Tan A. , Azzam Diana J. , Wander Seth A. , Wang Bin , Ergonul Burcu , Datar Ram H. , Cote Richard J. , Howard Guy A. , El-Ashry Dorraya , Torné-Poyatos Pablo , Marchal Juan A. , Slingerland Joyce M.
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Table S1 from Enhanced Survival with Implantable Scaffolds That Capture Metastatic Breast Cancer Cells In Vivo
Authors: Rao Shreyas S. , Bushnell Grace G. , Azarin Samira M. , Spicer Graham , Aguado Brian A. , Stoehr Jenna R. , Jiang Eric J. , Backman Vadim , Shea Lonnie D. , Jeruss Jacqueline S.
Published: April 2023

Characterization of micro-porous PLG and PCL scaffolds (N = 10).
Supplementary Figures 1-4 from Dual HER2 Targeting with Trastuzumab and Liposomal-Encapsulated Doxorubicin (MM-302) Demonstrates Synergistic Antitumor Activity in Breast and Gastric Cancer
Authors: Espelin Christopher W. , Leonard Shannon C. , Geretti Elena , Wickham Thomas J. , Hendriks Bart S.
Published: April 2023

Supp. Figure 1 MM-302 and trastuzumab co-localize in BT474-M3 xenograft tumors. Supp. Figure 2 In vivo deposition of MM-302 is specifically increased by trastuzumab or T-DM1. Supp. Figure 3 Pharmacokinetics (PK) of MM-302 remains the same with or without co-administration of trastuzumab. Supp. Figure 4 Combination of MM-302 and trastuzumab demonstrates synergistic anti-tumor activity in models of HER2-positive breast and gastric cancer.
Supplementary Figure Legends 1-4 from Dual HER2 Targeting with Trastuzumab and Liposomal-Encapsulated Doxorubicin (MM-302) Demonstrates Synergistic Antitumor Activity in Breast and Gastric Cancer
Authors: Espelin Christopher W. , Leonard Shannon C. , Geretti Elena , Wickham Thomas J. , Hendriks Bart S.
Published: April 2023

Supp. Figure 1 MM-302 and trastuzumab co-localize in BT474-M3 xenograft tumors. Supp. Figure 2 In vivo deposition of MM-302 is specifically increased by trastuzumab or T-DM1. Supp. Figure 3 Pharmacokinetics (PK) of MM-302 remains the same with or without co-administration of trastuzumab. Supp. Figure 4 Combination of MM-302 and trastuzumab demonstrates synergistic anti-tumor activity in models of HER2-positive breast and gastric cancer.
Supplementary Figure S4 from H3K27 Demethylase JMJD3 Employs the NF-κB and BMP Signaling Pathways to Modulate the Tumor Microenvironment and Promote Melanoma Progression and Metastasis
Authors: Park Woo-Yong , Hong Beom-Jin , Lee Jungsul , Choi Chulhee , Kim Mi-Young
Published: April 2023

STC1 and CCL2 expression are positively correlated with JMJD3 expression level in human malignant melanoma.
Supplementary figure legends from MFG-E8 Drives Melanoma Growth by Stimulating Mesenchymal Stromal Cell–Induced Angiogenesis and M2 Polarization of Tumor-Associated Macrophages
Authors: Yamada Kazuya , Uchiyama Akihiko , Uehara Akihito , Perera Buddhini , Ogino Sachiko , Yokoyama Yoko , Takeuchi Yuko , Udey Mark C. , Ishikawa Osamu , Motegi Sei-ichiro
Published: April 2023

This file contains the legends for the two supplementary figures.
Supplementary Table S13 from Transcriptome Analysis of Recurrently Deregulated Genes across Multiple Cancers Identifies New Pan-Cancer Biomarkers
Authors: Kaczkowski Bogumil , Tanaka Yuji , Kawaji Hideya , Sandelin Albin , Andersson Robin , Itoh Masayoshi , Lassmann Timo , Hayashizaki Yoshihide , Carninci Piero , Forrest Alistair R.R.
Published: April 2023

The genomic overlap of differentially expressed promoters and repetitive elements from RepeatMasker.
Supplementary Materials and Methods from AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation
Authors: Li Chia-Wei , Xia Weiya , Lim Seung-Oe , Hsu Jennifer L. , Huo Longfei , Wu Yun , Li Long-Yuan , Lai Chien-Chen , Chang Shih-Shin , Hsu Yi-Hsin , Sun Hui-Lung , Kim Jongchan , Yamaguchi Hirohito , Lee Dung-Fang , Wang Hongmei , Wang Yan , Chou Chao-Kai , Hsu Jung-Mao , Lai Yun-Ju , LaBaff Adam M. , Ding Qingqing , Ko How-Wen , Tsai Fuu-Jen , Tsai Chang-Hai , Hortobagyi Gabriel N. , Hung Mien-Chie
Published: April 2023

Supplementary Materials and Methods
Supplementary Figure Legends S1-S8 from Formation of Renal Cysts and Tumors in Vhl/Trp53-Deficient Mice Requires HIF1α and HIF2α
Authors: Schönenberger Désirée , Harlander Sabine , Rajski Michal , Jacobs Robert A. , Lundby Anne-Kristine , Adlesic Mojca , Hejhal Tomas , Wild Peter J. , Lundby Carsten , Frew Ian J.
Published: April 2023

Contains figure legends for the Supplementary Figures S1-S8
Table S5 from RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non–Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway
Authors: Dubois Fatéméh , Keller Maureen , Calvayrac Olivier , Soncin Fabrice , Hoa Lily , Hergovich Alexander , Parrini Maria-Carla , Mazières Julien , Vaisse-Lesteven Mélissa , Camonis Jacques , Levallet Guénaëlle , Zalcman Gérard
Published: April 2023

Gene transcription variations after RASSF1A depletion in HBEC3 Cells using RT2 ProfilerTM Cell motility PCR Array (Qiagen). RNA isolated from HBEC-3 cells transfected with Si RASSF1A or Si Neg was reverse transcribed and relative gene expression data was obtained using the Human Cell motility PCR Arrays. The expression profile of 84 genes relevant to cell motility as well as 5 housekeeping genes was assayed. Fold change calculations were done using SABiosciences' data analysis software which automatically calculates the fold change in gene expression between the treated and control groups.
Supplemental Figure S1 from Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem–like Cells
Authors: Giraud Julie , Failla Laura M. , Pascussi Jean-Marc , Lagerqvist Ebba L. , Ollier Jérémy , Finetti Pascal , Bertucci François , Ya Chu , Gasmi Imène , Bourgaux Jean-François , Prudhomme Michel , Mazard Thibault , Ait-Arsa Imade , Houhou Leila , Birnbaum Daniel , Pélegrin André , Vincent Charles , Ryall James G. , Joubert Dominique , Pannequin Julie , Hollande Frédéric
Published: April 2023

ALDHhigh CRC cells display CSC characteristics and elevated progastrin expression.
Supplementary Figure 4 from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses
Authors: Shono Yusuke , Tuckett Andrea Z. , Liou Hsiou-Chi , Doubrovina Ekaterina , Derenzini Enrico , Ouk Samedy , Tsai Jennifer J. , Smith Odette M. , Levy Emily R. , Kreines Fabiana M. , Ziegler Carly G.K. , Scallion Mary I. , Doubrovin Mikhail , Heller Glenn , Younes Anas , O'Reilly Richard J. , van den Brink Marcel R.M. , Zakrzewski Johannes L.
Published: April 2023

IT-901 is a more potent c-Rel inhibitor than IT-603.
Supplemental Figure 3 from M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers
Authors: Ohashi Yoshimi , Okamura Mutsumi , Hirosawa Asaka , Tamaki Naomi , Akatsuka Akinobu , Wu Kuo-Ming , Choi Hyeong-Wook , Yoshimatsu Kentaro , Shiina Isamu , Yamori Takao , Dan Shingo
Published: April 2023

Effect of M-COPA on cell surface expression of EGFR in MET-unamplified GC cell lines.
Supplementary Figure 1 from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses
Authors: Shono Yusuke , Tuckett Andrea Z. , Liou Hsiou-Chi , Doubrovina Ekaterina , Derenzini Enrico , Ouk Samedy , Tsai Jennifer J. , Smith Odette M. , Levy Emily R. , Kreines Fabiana M. , Ziegler Carly G.K. , Scallion Mary I. , Doubrovin Mikhail , Heller Glenn , Younes Anas , O'Reilly Richard J. , van den Brink Marcel R.M. , Zakrzewski Johannes L.
Published: April 2023

Analysis of the biochemical efficacy of IT-901 by electrophoretic mobility shift assay (EMSA) and NF-κB DNA binding ELISA.
Supplementary Tables from MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin
Authors: O'Brien Rosemary , Tran Sieu L. , Maritz Michelle F. , Liu Bing , Kong Cheng Fei , Purgato Stefania , Yang Chen , Murray Jayne , Russell Amanda J. , Flemming Claudia L. , von Jonquieres Georg , Pickett Hilda A. , London Wendy B. , Haber Michelle , Gunaratne Preethi H. , Norris Murray D. , Perini Giovanni , Fletcher Jamie I. , MacKenzie Karen L.
Published: April 2023

Supplementary Table 1: siRNA sequences Supplementary Table 2: qRT-PCR primers Supplementary Table 3: Primers for chromatin immunoprecipitation Supplementary Table 4: Multivariate analysis of event free survival and overall survival of neuroblastoma patients
Supplementary Figures from MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin
Authors: O'Brien Rosemary , Tran Sieu L. , Maritz Michelle F. , Liu Bing , Kong Cheng Fei , Purgato Stefania , Yang Chen , Murray Jayne , Russell Amanda J. , Flemming Claudia L. , von Jonquieres Georg , Pickett Hilda A. , London Wendy B. , Haber Michelle , Gunaratne Preethi H. , Norris Murray D. , Perini Giovanni , Fletcher Jamie I. , MacKenzie Karen L.
Published: April 2023

Supporting data; Supplementary Figure 1:Correlation analysis of DKC1 mRNA and dyskerin protein quantity in neuroblastoma cell lines Supplementary Figure 2:Correlation analysis of telomerase activity gene expression in neuroblastoma cells Supplementary Figure 3:Correlation analysis of TERT and MYC gene expression in neuroblastoma tumor samples Supplementary Figure 4:High DKC1 expression is a marker of poor prognosis in neuroblastoma Supplementary Figure 5:Analysis of TERT expression in neuroblastoma tumor samples Supplementary Figure 7: Upregulation of p21cip1 in NB69, but not SK-N-BE(2) cells following down regulation of dyskerin Supplementary Figure 8: Cell cycle and viability following downregulation of dyskerin