bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of phenotypic diversity in Anacamptis coriophora (Orchidaceae) populations from South Romania
Authors: NICULESCU Mariana , IANCU Paula , NUȚĂ Ilie S. , PĂNIȚĂ Ovidiu F.
Published: June 2023

Romanian flora includes a high diversity of orchids, any with a high conservationist interest, but many 0f themnot yet sufficiently investigated from an ecological, phytosociological or genetic point of view. Phenotypically analysis is also scarce and only a few data have been published in relation to the effects of site factors on the morphological and anatomical characteristics of the family Orchidaceae. This study analyses the variability of two populations of Anacamptis coriophora, based on their coenological affiliations, morphological observations and biometrical measurements. The data were collected from two grassland areas in Romania Stoenesti, Vâlcea County and Cobia, Dâmbovița County. The results showed that both populations are influenced by temperature, light and humidity and develop normally under optimal conditions. In the most favorable conditions encountered in Vâlcea county, orchids offer the splendor of flowers for a long time. Orchids in our country usually bloom in March, sometimes lasting until August, they have a delicate appearance, varied colors and the most diverse perfumes. The information obtained regarding the morphological diversity of the two populations could be suitable for designing strategies for their conservation in both locations.
The impact of cultivation system on nutritional quality of Jerusalem artichoke tubers cultivated in semiarid marginal areas
Authors: DIMA Milica , DIACONU Aurelia , PARASCHIVU Mirela , COTUNA Otilia , SĂRĂȚEANU Veronica , BONCIU Elena , SĂLCEANU Călin , OLARU Aurel L.
Published: June 2023

Jerusalem artichoke grows underground tubers that store fructans, primarily inulin, which are considered as prebiotics and functional dietary fibre with positive physiological benefits on human health. The aim of this study was to assess the yield and nutritional quality of Jerusalem artichoke tubers according to different cropping systems on dry sandy soils from Southern Romania. The experiments were carried out during 2018-2020 at the Research and Development Station for Plant Culture on Sands Dăbuleni, using a randomized complete block design with three replications. The experimental combined factors applied were fertilization with plants density (5×2). After the tubers were harvested, their quality was evaluated using standard methods. The results suggest that Jerusalem artichoke crop has minimal requirements for fertilization and tolerates very well high plants density without affecting significantly the yield and the nutritional features analysed, respectively the contents in total dry matter, soluble dry matter, inulin, soluble carbo-hydrates and C vitamin. A significant positive correlation was determined between the soluble dry matter and soluble carbohydrates content.  The assessed biochemical compounds displayed high values in both fertilized and unfertilized conditions and in both densities, showing that Jerusalem artichoke is a perennial crop with multifunctional high growing potential in marginal terrains usually improper for the conventional crops.
Physiological traits and metabolic profiles of contrasting rice cultivars under mild salinity stress during the seedling stage
Authors: JUMPA Thitiwan , PHETCHARABURANIN Jutarop , SUKSAWAT Manida , PATTANAGUL Wattana
Published: June 2023

This study aimed to investigate the effects of mild salinity stress on some physiological traits and metabolic profiles of rice during the seedling stage. Three rice cultivars differing in salinity stress response, ‘KDML105’ (salt-sensitive, local Thai jasmine rice), ‘IR29’ (salt-sensitive rice), and ‘Pokkali’ (salt-tolerant rice), were subjected to mild salinity stress by flood-irrigated with 40 mM NaCl. Salinity stress significantly reduces the growth and biomass of the sensitive cultivars. Electrolyte leakage in ‘KDML105’ and ‘IR29’ also increased significantly while the relative water content (RWC) decreased. However, salinity stress did not affect growth, electrolyte leakage, and RWC in the tolerant cultivar. Salinity significantly increased Na+/K+ ratio in shoot and root of all cultivars. Nevertheless, the increase of Na+/K+ ratio in ‘KDML105’ and ‘IR29’ was higher than that of ‘Pokkali’. The metabolic profile analysis of ‘KDML105’ showed that uracil, L-proline, malonate, L-carnitine, L-lactate, and guanine were significantly increased, but the levels of dihydroxyacetone and glycine were significantly decreased under salinity conditions. In ‘IR29’, L-proline, melatonin, gamma-aminobutyrate, and acetate were significantly increased. In ‘Pokkali’, however, sugar alcohols and sugars were slightly increased when exposed to salinity conditions. The metabolic pathway analysis revealed one involved metabolic pathway of ‘KDML105’: aminoacyl-tRNA biosynthesis, and three involved those of ‘IR29’: arginine proline metabolism, sulfur metabolism, and butanoate metabolism. The difference in the metabolic profile of the salt-tolerance salt-sensitive cultivars provides new insights to identify additional novel biomarkers that will help better understand the mechanisms for salt tolerance in rice.
EDUCATIONAL POLICY IN THE STATE OF SÃO PAULO UNDER THE NEW PUBLIC MANAGEMENT (1995-2018)
Authors: JACOMINI MÁRCIA APARECIDA , NASCIMENTO IRACEMA SANTOS DO , STOCO SERGIO
Published: June 2023

ABSTRACT: The article analyses the educational policy of São Paulo State between 1995-2018, period that comprises six mandates of Brazilian Social Democracy Party. The corpus of data was made up of the main programs and projects of each mandate. As a theoretical reference that supported the analysis, the concepts of Gramsci’s integral state and hegemony of the dominant classes’ ideology, and the theory of Punctuated Equilibrium were used. Academic studies on some of the programs and projects were also consulted. It was found that the management paradigm adopted by the Secretary of Education since the first term was that of the New Public Management, in line with the option made by the Fernando Henrique Cardoso government at the federal level, in turn aligned with the international order of capitalist system of production. Among the conclusions of the analysis, the following can be highlighted: the implementation of such a management model has been adjusted, expanded and deepened over the successive mandates; resistance, as this does not happens without tensions, dissidents and internal conflicts, such as difficulties and some defeats imposed by questioning movements; the opposition to the constitutional principle of democratic management of public education and the progressive autonomy of the school as determined by the Law of Directives and Bases of National Education. In summary, this management concept, based on business logic, on centralized formulation and decisions and the vertical delegation of tasks to the school, has not been able to fulfil the promise of improving the quality of education.
MACROSCOPIC AND HISTOLOGICAL ANALYSIS ON ENDOSCOPICALLY RESECTED RECTAL LESIONS
Authors: Frugis Marcos Onofre , Ribas Carmen Australia Paredes Marcondes , Malafaia Osvaldo , Tabushi Fernando Issamu , Czeczko Nicolau Gregori
Published: June 2023

ABSTRACT BACKGROUND: Colorectal cancer is among the most common malignancies worldwide. Colonoscopy is the examination of choice for the prevention of CRC because of its great diagnostic and, especially, therapeutic capacity in relation to adenomatous lesions. AIMS: This study aimed to analyze the prevalence, macroscopic, and histological characteristics of polypoid rectal lesions resected through endoscopic techniques and assess whether endoscopic therapy is safe and efficient for treating lesions located in the rectum. METHODS: This is a retrospective observational study with an analysis of the medical records of all patients undergoing resection of rectal polyps. RESULTS: A total of 123 patients with rectal lesions were evaluated, with 59 men and 64 women of mean age 56 years. All patients underwent endoscopic resection: 70% with polypectomy and 30% with wide mucosectomy. Complete colonoscopy with removal of the entire rectal lesion occurred in 91%, while in 5% the preparation was inadequate and poor clinical conditions were an impeditive factor, and in 4% surgical treatment was indicated because there was an infiltrative lesion with central ulceration. Histological evaluation showed adenomas in 3.25%, hyperplasia in 7.32%, and hamartoma in 0.81%; low-grade dysplasia was identified in 34.96%, high-grade dysplasia in 51.22%, and adenocarcinoma in 1.63%, while one case (0.81%) was classified as erosion. CONCLUSIONS: Polyps in the rectum are common and were found in 37% of these colonoscopies. Adenomas with dysplasia were the most common form of Colorectal cancer . Therapeutic colonoscopy proved to be a safe and efficient method for the complete treatment of rectal lesions.
Perfil epidemiológico e distribuição espacial dos casos de hanseníase na Paraíba
Authors: Véras Gerlane Cristinne Bertino , Soares Maria Júlia Guimarães Oliveira , Silva Luiz Henrique da , Moraes Ronei Marcos de
Published: June 2023

Resumo Introdução A hanseníase se apresenta de forma heterogênea, o que requer o reconhecimento do perfil e distribuição espacial para a efetivação de ações de controle. Objetivo Descrever o perfil epidemiológico e a distribuição espacial dos casos de hanseníase na Paraíba. Método Estudo ecológico, de base secundária e abordagem quantitativa. Os loci do estudo foram os 223 municípios do estado. Os dados foram coletados no Sistema de Informação de Agravos de Notificação/Hanseníase correspondentes ao período de 2015 a 2019. Utilizou-se de estatística descritiva e análise espacial com auxílio do software R. Resultados Foram analisados 3.218 casos para o perfil epidemiológico e 3.212 para a análise espacial. Verificou-se maior registro no ano de 2019 (n=778;24,2%); no sexo masculino (n=1.783; 55,5%); faixa etária 40 a 59 anos (n=1.236; 38,4%); classificação multibacilar (n=2.095; 65,2%); forma dimorfa (n= 970; 30,2%), e grau de incapacidade física 0 (n=1.611; 50,2%). Identificaram-se 171 (76,7%) municípios que notificaram casos, e houve detecção de conglomerados simples e compostos envolvendo 31 municípios, situados mais ao Leste e Oeste do estado. Conclusão Ressalta-se que a hanseníase permanece com cadeia de transmissão ativa na Paraíba e com distribuição geográfica heterogênea, reafirmando a importância de planejar e executar ações de controle mais resolutivas.
Works analogous to slavery: an analysis of slaves in the 21st century in Brazil
Authors: GAMA FERNANDA CAVALCANTE , SILVA PRISCILA THAYANE DE CARVALHO , GARCIA FABIANE MAIA , JESUS AUDRILENE SANTOS DE
Published: June 2023

Abstract This article proposes a reflection on Brazil and its works analogous to slavery that has been widely used within the business practices of global capital and is a topic little explored in administration research. The article analyzes the unfolding of works analogous to slavery in the 21st century. This qualitative study consists of a bibliographic and documentary research based on the perspective of dialectical and historical materialism. It analyzes secondary data from infraction notices from the Ministry of Labor and Welfare, the ministry’s list of companies engaged in slave labor, and data from Radar SIT (statistics and information dashboard of labor inspection in Brazil) between 1995 and 2022. In addition, this study collected information from journalistic articles that portrayed inspections of modern slave labor, thus enabling examples of this practice in contemporary times. The findings show that the very lack of more assertive public policies and the fragility of the criminal applicability of Brazilian legislation have challenged the eradication of modern slave labor in the country.
Racismo, sexismo e resquícios do escravismo em anúncios de empregos
Authors: REZENDE ANA FLÁVIA , ANDRADE LUÍS FERNANDO SILVA
Published: June 2023

Resumo Anúncios de empregos podem apresentar elementos de opressão de raça, ainda que sutilmente, em expressões como ‘boa aparência’ e ‘boa higiene’. Tal constatação nos faz refletir que o mercado de trabalho, assim como a sociedade em geral, é racialmente estruturado não apenas na permanência e ascensão profissional de mulheres negras, mas até mesmo no recrutamento, do qual os anúncios de emprego on-line fazem parte. Na presente pesquisa, partimos do objetivo de compreender como a publicação de anúncios de emprego que trazem em si características fenotípicas e relacionadas a ‘boa aparência’ contribuem para a perpetuação do racismo e do sexismo. Especificamente, almejamos compreender como se dá a resistência às práticas e à estrutura racista do mercado de trabalho. Recorremos a referenciais de decolonialidade e interseccionalidade e utilizamos a análise temática em um corpus de 285 anúncios de emprego, 4 sites de classificados e 4 iniciativas de empregabilidade negra presentes no LinkedIn. Nos resultados e discussão, indicamos que um ideal de trabalhadora branca perpetua-se no mercado de trabalho doméstico e que boa imagem e boa higiene são expressões eufemísticas que mascaram o racismo presente no mercado de trabalho, manifestando resquícios do escravismo. Ainda assim, iniciativas atuais de empregabilidade negra buscam trazer à tona a necessidade de pensar ações afirmativas para homens e mulheres negros, historicamente excluídos de empregos de maior prestígio e remuneração, assim como de espaços de decisão. Esse movimento entre opressão, resistência e existência negra opera um projeto decolonial de intervenção na realidade, principal contribuição da presente pesquisa.
The contributions of Clóvis Moura’s interpretation of slavery in Brazil and the possible dialogues with organization studies
Authors: DUARTE RICARDO MELLO
Published: June 2023

Abstract This study retakes some important points of the oeuvre of Clóvis Moura and delineates ways for its use in organization studies. Based on a perspective that places the racial issue at the center of social formation, it is possible to take some distance from approaches that relate “backwardness” in the periphery of capitalism to faulty administrative practices. The elements selected from Moura’s work were the emphasis on the role of the enslaved rebellion as an element of the slavery system erosion; the criticism of contemporary techniques of professional, cultural, and political selection; the role of dynamic social praxis; and the relationship between racial issues and economic dependence. The study identifies bridges between these ideas and organization studies, making it possible to i) question contemporary readings that place those that dominate as the protagonist of eventual social transformations by recognizing the potential of those who are dominated to recover their autonomy; ii) analyze how organizations are decisive spaces for inequality reproduction, pointing to the idea of promoting diversity in companies as a component of the myth that hides social reality; iii) reflect on how contemporary resistance movements, inspired by quilombagem, can be thought of from their capacity to erode the current system from connecting marginalized groups; iv) reflect on how the super-exploitation of work, allied to state economic austerity and police and parastatal violence, shows how the legacy of slavery adapts to continue reproducing and coordinating the dependent capitalism in the face of new artifacts and organizational arrangements.
Coleção de coleções: breve relato da constituição do acervo digital on-line do Programa Cinema & Educação
Authors: Oliveira Junior Wenceslao Machado , Palma Luciane Vieira , Souza Eliana da Silva , Coimbra Joice Ribeiro Souza
Published: June 2023

Resumo O artigo relata e discute o processo de criação do acervo cinematográfico digital do Programa Cinema & Educação, da Prefeitura Municipal de Campinas, que conta com doze coleções com acesso público e gratuito; e indica as escolhas educativas, as parcerias e dificuldades na curadoria do acervo. Como gesto voltado a atuar no sonhado processo de regulamentação da Lei nº 13.006/2014, a coleção visa ampliar a cultura docente acerca dos curtas-metragens de produção nacional, especialmente os realizados localmente como gesto artístico. Paralelamente, são apresentadas as referências para o modo de organização do acervo digital a partir do conceito de coleção.
Do uno ao múltiplo: as didáticas de Comenius e de Montaigne e a diversidade e suas contribuições para a contemporaneidade
Authors: Coppi Luiz Antonio Callegari
Published: June 2023

Resumo Na profusão textual derivada da prensa de Gutenberg, Comenius e Montaigne elaboram reflexões pedagógicas que, de forma mais ou menos evidente, debruçam-se sobre a diversidade de opiniões e de interpretações e propõem como lidar com ela. O primeiro busca neutralizá-la afirmando a palavra divina como única e, portanto, critério para a definição do que é pertinente no interior das escolas; o segundo aposta na "frequentação do mundo" e na potência que essa variedade tem de dar contornos mais modestos e responsáveis àquilo que se sabe. Neste artigo, pretende-se apresentar esses dois encaminhamentos com vistas a refletir sobre como podem contribuir para pensar a sala de aula contemporânea também atravessada por múltiplos discursos, verdadeiros ou não, oriundos das tecnologias digitais.
CRIPTOMOEDAS E SISTEMA FINANCEIRO: REVISÃO SISTEMÁTICA DE LITERATURA
Authors: Senna Viviane de , Souza Adriano Mendonça
Published: June 2023

RESUMO As criptomoedas são ativos com transações gerenciadas por novos métodos se comparados a transações tradicionais mediadas pelas bolsas de valores. A inserção desses ativos pode modificar o sistema econômico. O objetivo do estudo é analisar um conjunto de artigos publicados em bases de dados internacionais de conteúdo científico sobre criptomoedas e as relações com as bolsas de valores para compreender a evolução da temática ao longo do tempo. A consulta foi realizada nas bases Scopus e Web of Science. Foram analisados 196 artigos que indicaram como evolução temática algoritmos de aprendizagem, negociação eletrônica, mercado financeiro e digital. Os principais estudos focaram a investigação do comportamento das criptomoedas diante de variáveis mercadológicas, criptomoedas como porto seguro ou diversificação, análise dos preços e do impacto do valor emocional nas criptomoedas. Os artigos mais relevantes, a rede de citações e cocitações possibilitaram o conhecimento dos autores Baur et al., 2018; Ji et al., 2020; Peng et al., 2018; Symitsi & Chalvatzis, 2019; Urquhart, 2017.
Targeting Amyloids with Coated Nanoparticles: A Review on Potential Combinations of Nanoparticles and Bio-Compatible Coatings
Authors: Warerkar Oshin D. , Mudliar Niyati H. , Momin Munira M. , Singh Prabhat K.
Published: June 2023

Amyloidosis is the major cause of many neurodegenerative diseases, such as, Alzheimer's and Parkinson's where the misfolding and deposition of a previously functional protein make it inept for carrying out its function. The genesis of amyloid fibril formation and the strategies to inhibit it have been studied extensively, although some parts of this puzzle still remain unfathomable to date. Many classes of molecules have been explored as potential drugs in vitro, but their inability to work in vivo by crossing the blood-brain-barrier has made them an inadequate treatment option. In this regard, nanoparticles (NPs) have turned out to be an exciting alternative because they could overcome many drawbacks of previously studied molecules and provide advantages, such as, greater bioavailability of molecules and target-specific delivery of drugs. In this paper, we present an overview on several coated NPs which have shown promising efficiency in inhibiting fibril formation. A hundred and thirty papers published in the past two decades have been comprehensively reviewed, which majorly encompass NPs comprising different materials like gold, silver, iron-oxide, poly(lactic-co-glycolic acid), polymeric NP, etc., which are coated with various molecules of predominantly natural origin, such as different types of amino acids, peptides, curcumin, drugs, catechin, etc. We hope that this review will shed light on the advancement of symbiotic amalgamation of NPs with molecules from natural sources and will inspire further research on the tremendous therapeutic potential of these combinations for many amyloid-related diseases.
Leakage through a circular geomembrane hole overlain and underlain by silty sand tailings
Authors: Fan J. , Rowe R. K.
Published: June 2023

Experiments are conducted to investigate leakage through circular GMB holes overlain and underlain by both tailings with various hole diameters and GMB thicknesses. Finite element analyses are performed to explore the effect of hydraulic conductivities (k) of subgrade (underliner) and tailings above the GMB (overliner) on water head contours dissipation. An analytical solution is developed for predicting leakage through circular GMB hole overlain and underlain by both tailings. Results show that the effect of subgrade on leakage is highly dependent on the ratio of k between the underliner and the overliner. If the ratio >100, no head loss occurs in the subgrade; if the ratio <0.01, all the head loss occurs in the subgrade. With the deposition of fines from overliner into subgrade, a low permeable filter cake is formed on the subgrade surface, notably increasing the impact of underliner on leakage. With the increasing ratio of k between underliner and overliner from 0.01, 0.1, 1, 10, and to 100, the ratio of leakage relative to a highly permeable subgrade increases from 0.01, 0.1, 0.56, 0.93, and to 1. An intimate interface contact can be achieved when the GMB is underlain by silty sand tailings as subgrade (foundation) material.
Assessing Students’ Multimodal Texts in the Subject of English: Synthesising Peers’ and Teachers’ Recognition of Semiotic Work
Authors: Ørevik Sigrid
Published: June 2023

While learning activities and text production in language subjects typically include multiple forms of multimodal expression, assessment in the subjects continues to a great extent to depend on students’ written texts. As a contribution to an increasing call for alignment of curricular activities and assessment, this article explores an approach to assessment of upper secondary students’ production of multimodal persuasive texts in the subject of English as an additional language (EAL). The article reports from a design-based study comprising two classroom interventions where assessment of students’ multimodal texts was conducted separately by peer groups and the teacher and researcher in collaboration, applying assessment criteria informed by multimodal social semiotic theory and operationalisations of communicative competence. Comparing the results of peer and teacher assessment of students’ multimodal persuasive texts, agreement was found relating to representational, interactional, and compositional aspects of the texts, whereas differences in views mostly concerned nuances in interpersonal aspects. Unpacking these nuances, the article concludes that peers’ and teachers’ assessments of multimodal texts complement each other in ways that can prompt fruitful discussions on meaning making in the light of context and social factors and thus contribute to heightened semiotic awareness and a broader recognition of the students’ communicative competence in the subject.
Effects of Concurrent Resistance and Aerobic Training on Body Composition, Muscular Strength and Maximum Oxygen Uptake in Men with Excess Weight
Authors: Namboonlue Chaiyawat , Namboonlue Sarocha , Sriwiset Palakorn , Jaisuk Jittima , Buttichak Arunya , Muangritdech Nattha , Saengjan Wisutthida
Published: June 2023

The study purpose was to compare the effects of concurrent resistance and aerobic training to resistance and/or aerobic training alone on body composition, muscular strength and maximum oxygen uptake in overweight and obese men.
Materials and methods. Twenty-four overweight and obese (BMI = 23.0 – 29.9 kg/m2) volunteers who were male students from Ubon Ratchathani Rajabhat University, aged 19-22 years were assigned into 3 groups: 1) resistance training group (RT), 2) aerobic training group (AT) and 3) concurrent resistance and aerobic training group (RT+AT). The training was 45 minutes per session and 2 days per week. Body composition along with muscular strength (1-RM) and maximum oxygen uptake (VO2max) were measured before (2-3 days prior) and after (2-3 days post) a 5-week training period.
Results. Waist circumference was significantly decreased in all three groups, but the RT+AT group also found improvement in percentages of fat-free mass (0.49 ± 0.49%, p = 0.021, mean ± SD) and skeletal muscle mass (1.01 ± 0.95%, p = 0.025) when compared to their baseline.  Similarly, 1-RM in leg extension was significantly increased in all three groups, while the RT group (47.67 ± 14.85%, p = 0.01) and the RT+AT group (42.08 ± 21.70%, p = 0.039) showed a substantially larger improvement in the 1-RM in leg extension when compared to the AT group (20.37 ± 13.97%). Finally, VO2max was significantly increased in all three groups (baseline to post-intervention), though they were not significantly different between groups.
Conclusions. Concurrent resistance and aerobic training can reduce waist circumference and increase fat-free mass, skeletal muscle mass, 1-RM and VO2max. Therefore, this training strategy may serve as a useful alternative way to improve overall physical fitness and health promotion in overweight to obese male population.
Molecular Docking Studies and ADME Predictions on Synthesized Chalcone Compounds Targeting EGFR
Authors: GÜNDOĞDU Özlem
Published: June 2023

In the present study, new chalcone derivatives (5a–5f) obtained from the condensation reaction of cuminaldehyde and acetophenone compounds containing different substituents were reported. Chemical characterization (1HNMR and 13CNMR analysis) and molecular docking studies of the synthesized compounds were performed against the epidermal growth factor receptor (EGFR) and reference drug (metachalcone). Erlotinib was used as the reference ligand. Compound 5 (-7.6 kcal mol-1), compound 6 (-7.38 kcal mol-1), and compound 7 (-7.44 kcal mol-1) were found to be the strongest inhibitors of EGFR when compared to Erlotinib (-7.0 kcal mol-1). In addition, an ADME estimation was made. It was determined that the synthesized compounds could be potent EGFR inhibitors compared to Erlotinib. Compounds 5-7 and the target protein showed a better binding affinity for EGFR than the reference compound (Erlotinib). The synthesized compounds can be potent inhibitors for EGFR-mutated cancers.
Cohort Establishment and Operation at Pusan National University School of Medicine
Authors: Yune So-Jung , Lee Sang-Yeoup , Im Sunju
Published: June 2023

Pusan National University School of Medicine (PNUSOM) began analyzing the cohort of pre-medical students admitted in 2015 and has been conducting purposeful analyses for the past 3 years. The aim of this paper is to introduce the process of cohort establishment, cohort composition, and the utilization of cohort analysis results. PNUSOM did not initially form a cohort with a purpose or through a systematic process, but was able to collect longitudinal data on students through the establishment of a Medical Education Information System and an organization that supports medical education. Cohort construction at our university is different in terms of a clear orientation toward research questions, flexibility in cohort composition, and subsequent guideline supplementation. We investigated the relevance of admission factors, performance improvements, satisfaction with the educational environment, and promotion and failure rate in undergraduate students, as well as performance levels and career paths in graduates. The results were presented to the Admissions Committee, Curriculum Committee, Learning Outcomes Committee, and Student Guidance Committee to be used as a basis for innovations and improvements in education. Since cohort studies require long-term efforts, it is necessary to ensure the efficiency of data collection for graduate cohorts, as well as the validity and ethics of the study.
Establishment of a Cohort at Chosun University College of Medicine for Social Accountability
Authors: Choi Hyoseon , Kim Youngjon , Yoo Hyo Hyun
Published: June 2023

Cohorts are established and operated at medical schools as part of efforts to improve the quality of education. Chosun University College of Medicine clarified the purpose of establishing three cohorts in light of its core values and developed criteria and indicators for each purpose. An organization focusing on cohort construction and operation was established as the Cohort Committee under the Quality Improvement Committee, and guidelines were proposed. In addition, a database and system were developed to handle primary data efficiently, and tools for measuring psychological variables were created. The data collected by establishing a cohort, regions, and admission types of graduates were first analyzed for the following projects: (1) an analysis of the educational process and quality improvement to educate medical professionals who contribute to the community after graduation, and (2) an analysis of the educational process and quality improvement to secure excellence in the medical field (e.g., knowledge and clinical reasoning), using information on the academic achievements of students and graduates as primary data. Chosun University College of Medicine is conducting cohorts and longitudinal studies gradually, starting with a simple, practically feasible system to solve the difficulties faced in cohort establishment and operation. Medical educators hope that future data collection and analysis will improve the quality of medical school education and have practical implications.
Symbiotic Dose-50 (SD50) for Vibrio fischeri strain to colonize Euprymna scolopes v1
Authors: not provided ard
Published: June 2023

This protocol details symbiotic dose-50 (SD50) for Vibrio fischeri strain to colonize Euprymna scolopes.
Adsorption of methylene blue dye onto alginate-bioglass membranes: response surface method, isotherm, and kinetic studies
Authors: TÜRE Hasan
Published: June 2023

In this research, environment-friendly composite membranes based on alginate (ALG) and bioglass nanoparticles (BGs) were prepared by the solvent casting technique and utilized as adsorbents for the elimination of methylene blue (MB) from water. Zeta potential of the particles was determined to be -24.9 mV by laser dynamic light scattering (DLS), and their sizes were found to be 773 and 777 nm by transmission electron microscopy (TEM) and DLS analysis, respectively. Atomic force microscope (AFM) analysis revealed that increasing the BGs content from 1 to 5% w/v caused the root mean square roughness of membranes to increase from 159.38 to 182.03 nm. The adsorption process was successfully modeled and optimized using a hybrid response surface methodology integrated central composite design (RSM-CCD). A statistical analysis was utilized to examine and optimize the effects of three important independent variables (concentration of BGs (1-5% w/v), pH of the solution (3-9), and initial dye level (15-45 mg L-1)) on MB adsorption performance. The findings indicated that the quadratic model was suitable for prediction of MB's removal. Optimized experimental parameters were found to be a pH of 9, a contact time of 120 min, an initial MB concentration of 45 mg L-1, and a BGs concentration of 1% (w/v). Freundlich isotherm and pseudo-second-order kinetic models were found to be the best-fitting models in isotherm and kinetic studies, respectively. Dubinin-Radushkevich (D-R) isotherm model predicted a chemical mechanism for MB adsorption onto the composite alginate membranes.
Tripan mavi boyasının fungal biyokütle ile biyosorpsiyonu hakkında bir çalışma
Authors: ARACAGÖK Yusuf Doruk
Published: June 2023

Tripan mavisi (TB) yaygın olarak kullanılan tehlikeli ve kanserojen bir boyadır. Bu araştırmanın amacı, ısıyla inaktive edilmiş Aspergilus niveus biyokütlesi kullanarak TB'yi gidermektir. TB boyasının biyosorpsiyonu pH, TB boyası konsantrasyonu, biyosorbent miktarı ve zamanın bir fonksiyonu olarak incelenmiştir. Çalışmalarda Langmuir, Freundlich, Redlich-Peterson ve Harkins-Jura izoterm modelleri uygunluk açısından değerlendirilmiştir. TB boyasının kullanılan biyokütle üzerindeki biyosorpsiyonunun Langmuir ve Redlich-Peterson izoterm modellerini takip ettiği bulunmuştur. Yalancı ikinci dereceden kinetik modelin TB biyosorpsiyonunu açıklamada daha etkili olduğu bulunmuştur. Sözde ikinci dereceden modelin teorik Qe değerinin (129,87 mg/g) 25 ℃'de deneysel olarak elde edilen değere (128,1 mg/g) yakın olduğu bulunmuştur. Çalışmalara göre, en yüksek biyosorpsiyon kapasitesi 45 ℃'de 141,79 mg/g olarak bulunmuştur.
Investigation on the Flow Behaviour of Agar Solution and Rheological Modelling
Authors: Karataş Mukaddes
Published: June 2023

In this study, the effect of shear rate, agar concentration (15-35 kg/m3) and temperature (30-60°C) on the apparent viscosity of the agar solution was investigated. Apparent viscosities at different shear rates were determined using a rotational viscometer. The findings show that the apparent viscosity decreasing with a rise of shear rate increased with increasing concentration. An increase in the tempearture, on the other hand, led to a decrease in the apparent viscosity. To illustrate both temperature and concentration changes together, the Bingham, power law, and Casson models were utilized in choosing the most suitable model. When the models were compared using statistical tests, the most compatible model was found to be the power-law model. The consistency coefficient and flow behaviour index calculated using the power law model showed that agar solutions exhibited shear-thinning flow behavior (pseudoplastic). This study suggests that power law, within the ranges of the temperature and concentration studied could be used to estimate the viscosity of the agar solutions in the applications requiring the knowledge of flow behavior.
Chaos in a Three-Dimensional Cancer Model with Piecewise Constant Arguments
Authors: Kartal Senol
Published: June 2023

In this study, we analyze a cancer model which includes the interactions among tumor cells, healthy host cells and effector immune cells. The model with continuous case has been studied in the literature and it has been shown that it exhibits chaotic behavior. In this paper, we aim to build a better understanding of how both discrete and continuous times affect the dynamic behavior of the tumor growth model. So, we reconsider the model as a system of differential equations with piecewise constant argument. To analyze dynamical behavior of the model, we consider the solution of the system in a certain subinterval which leads to the system of difference equations. Some theoretical results are obtained for local behavior of the system. In addition, we study chaotic dynamic of the system through Neimark-Sacker bifurcation by using Lyapunov exponents
Chemical Reactivities and Organic Light-emitting Diode Properties of some Polyaromatic Molecules
Authors: Elik Mustafa
Published: June 2023

High-performance organic-light emitting diode (OLED) display panels have been very popular lately due to their many advantages compared to liquid-crystal display (LCD) and light-emitting diode (LED) panels. It is also well known that the materials used in OLED panels are important in determining OLED performance. Starting with the selection of materials which have rich π-electrons will be a good start for the design of high-performance OLED materials. For this aim, the OLED properties of some cyclic aromatic structures with rich π-electrons such as 2,2ꞌ-bi-1,6-naphthyridine (BNP), 1,6-bis(4ꞌ-pyridine)-2,5-diazahexane (BPDH), 3,3ꞌ-bis[3-(2-pyridyl)pyrazol-1-yl]biphenyl (BPPB), 5,5ꞌ-dicyano-2,2ꞌ-bipyridine (DCBP), 2,2ꞌ-dimethyl-4,4ꞌ-bipyrimidine (DMBP), and 4ꞌ-phenyl-2,2ꞌ:6ꞌ2ꞌꞌterpyridine (Ph-TERPY) were theoretically analyzed using computational chemistry tools. The calculations of monomeric and dimeric structures of mentioned molecules were carried out at B3LYP/6-31G(d) and B3LYP/TZP levels, respectively. The OLED properties of the investigated compound were explained by means of OLED parameters such as the reorganization energies, adiabatic-vertical ionization potentials and adiabatic-vertical electron affinities, the effective transfer integrals, and the charge transfer ratios. In the light of computational chemistry, it is indicated that these studied molecules will be utilized in which layers of OLED device. In addition to OLED analysis, in the light of the calculated reactivity descriptors, the chemical reactivities of the studied molecules were discussed.
The Impact of Health Promotion about E-cigarettes Risk among Adolescents
Authors: Mawarni Dian , Masyiyah Shofiyatul , Yunita Anis , Maharani Nazira Dyah
Published: June 2023

The increasing prevalence of cigarette users in the younger generation is clear evidence that cigarettes are increasingly popular, especially e-cigarettes. Misinformation and misperceptions circulating in the community as well as the role of the media add to concerns about the impact that e-cigarettes can have. Therefore, a transformation of health promotion efforts to save future generations from the dangers of e-cigarettes is needed. This study aimed to analyze the effect of health promotion media in reducing the willingness to smoke e-cigarettes in adolescents. This study used a quantitative analytic design with primary data. The instrument used was a questionnaire which was filled out independently by the respondents. Data collection was carried out online using a small group trial. Data analysis was using Mc Nemar test. The bivariate analysis showed that the three challenges had an impact in the form of increasing knowledge and perceptions. On the knowledge variable, the whole challenge gave a significant increase with the results of sig. 0.025 on the challenge of providing visual media socialization, sig. 0.014 on the challenge of providing audio-visual media socialization, and sig. 0.008 on the active participation challenge. Adolescent perceptions also increased before and after a series of challenges was given. The provision of health promotion with these three challenges had a significant difference of sig. 0.031 on adolescent perceptions. There were differences in adolescent knowledge and perceptions of e-smoking behavior through the using of health promotion media. The most effective method used in changing the knowledge and perceptions of adolescents is to use the active participation of adolescents.
Portada e índice
Authors: Equipo Editorial BAc
Published: June 2023

Portada e índice
Inteligencia de negocios y agilidad organizacional: ¿Son relevantes la toma de decisiones racional e intuitiva?
Authors: Gómez-Duque Luis Ángel , Daza-Torres José David , Arias-Pérez José
Published: June 2023

El objetivo de este trabajo fue analizar el efecto mediador de la toma de decisiones racional e intuitiva en la relación entre inteligencia de negocios y agilidad organizacional. El modelo se testeó en una muestra de empresas intensivas en conocimiento mediante ecuaciones estructurales. En cuanto a los resultados, la inteligencia de negocios necesita apoyarse en procesos racionales para potenciar su incidencia en la agilidad organizacional, porque el conocimiento del entorno generado por la inteligencia de negocios se aprovecha más cuando pasa por un proceso analítico, sistemático y basado en reglas que cuando pasa por un proceso basado en la experiencia y la percepción. En otras palabras, en ese escenario la toma de decisiones racional convierte los insumos que arroja la inteligencia de negocios en respuestas organizacionales más acertadas y ágiles.
The efficacy of Persian Version of Mindfulness-Based Stress Management app (Aramgar) for college’s mindfulness skills and perceived stress
Authors: Borjalilu Somaieh
Published: June 2023

Functional mobile applications are regarded as one of the brand-new approaches to psychological interventions in different areas, including stress. The study aims to analyze a mobile application for Persian users on perceived stress and improve mindful skills. This study was a one-group pretest-posttest design with a quasi-experimental research design. Three instruments were used in this study: the Five Factor Mindfulness Questionnaire (FFMQ), the Perceived Stress Scale (PSS-10), and the Mobile App Rating Scale (MARS). Eighty-five students participated in an 8-week mindfulness mobile app (Aramgar) for at least 10 minutes per day  intervention. They responded to validated outcome measures of stress and mindfulness at baseline after the 8-week continued access period. The mobile application, Aramgar, was designed based on Mindfulness-based stress reduction. Paired t-tests showed significant differences in general perceived stress (P = 0.03) and total score of mindfulness (P = 0.002) before and after Aramgar. The results of analyzing the quality of Aramgar in terms of engagement, functionality, aesthetics, and information quality showed that specialists assessed the quality of the application appropriately. Using functional mobile apps provides ease of use for mental health services. Therefore, to strengthen and develop the mentioned services, it is recommended that the necessary information technology infrastructures be provided and the existing limitations for designing and running mental health mobile apps be removed.
Forgiveness Therapy to Improve Subjective Well-Being Among Families of Patients with Chronic Illness
Authors: Diana Raden Rachmy , Nashori Fuad , Pihasniwati Pihasniwati
Published: June 2023

Families (caregivers) of patients with chronic illness should ideally have high subjective well-being to care for chronic illness patients well. In reality, they cry frequently, look pensive, and have difficulty carrying out daily activities. This quasi-experimental study aims to examine the effect of forgiveness therapy on increasing the subjective well-being of families (caregivers) of patients with chronic illness. There were 11 participants (3 males and 9 females) divided into two groups, i.e., the treatment group consisting of 6 persons (1 male and 5 females) and the control group consisting of 5 persons (2 males and 3 females) who have looked after the patients with chronic illness for 2–8 years. The subjective well-being was measured by the Satisfaction with Life Scale (SWLS) and the Positive Affect Negative Affect Schedule (PANAS). The data were then analyzed using Mann-Whitney to compare means. The results showed differences in subjective well-being between the treatment and control groups. The results showed that forgiveness therapy has effectively improved subjective well-being in families or patients with chronic illness. Based on the results, the researcher suggested that forgiveness therapy can be used to provide psychological interventions to families of patients with chronic illnesses. Families still need support to optimize and stabilize the patient’s health condition
Comparative outcome of socket shield method and conventional immediate implant implantation with immediate temporization- a 10 years follow-up
Authors: Khan Abdullah Al Mamun , Zahan Nasrin Parvin
Published: June 2023

Background: Dental implants are now regarded as an effective treatment option for replacing missing teeth. The objective was to evaluate the socket shield approach with immediate temporization to the conventional instantaneous implant with immediate temporization utilizing the parameters of horizontal and vertical dimensional bone loss, crestal bone thickness (CBT) and pink esthetic score (PES).
Methods: This prospective study was carried out at Banasree Dental and German Dental implant surgery centers from December 2010 to December 2020 where 74 patients who had non-restorable maxillary teeth in the esthetic region were conducted and evaluated for implant settlement. The allocated individuals were divided into two groups immediate implant with socket shield group (study group, n=22) and the conventional immediate implant placement group (control group, n=52). SPSS version 21.0 was used to analyze all of the data.
Results: Mean value of crestal bone thickness (CBT) at the pre-operative time was 1.31±0.2 in both groups but at the 6 months follow-up time it was 1.2±0.22 and 1.07±0.21, at the 24 months follow-up time it was 1.13±0.24 and 0.99±0.20 and at the 60 months follow-up time in was 1.05±0.27 and 0.79±0.15 and at the 120 months follow-up time it was 1.03±0.29 and 0.69±0.17 in the study and control group respectively. In the study group, the mean value of pink esthetic score was 11.45±1.6 at 6 months follow-up time, 12±0.89 at 24 months, 12.5±0.87 at the 60 months and 12.5±0.86 at the 120 months follow-up time whereas in the control group, it was 11±1.32, 10±1.52, 8.9±1.63 and 7.5±1.55, respectively.
Conclusions: The SST group revealed minimal reduction in CBT, horizontal and vertical bone loss and a superior PES compared to conventional immediate implant.
Characteristics of brain MRI abnormalities associated with symptomatic internal carotid artery stenosis: a retrospective single-center study
Authors: Usman Frits S. , Kurniawan Adrian , Pujiastono Eko S. , Mianoki Adika , Kastilong Merlin P.
Published: June 2023

Background: Carotid artery stenosis (CAS) may manifest with stroke, transient ischemic attack (TIA), or more covert non-hemispheric symptoms. While symptoms can be subtle, brain MRI abnormalities may already reflect substantial changes. This study aimed to determine the association between brain MRI abnormalities and symptomatic CAS.
Methods: A retrospective cross-sectional study was conducted to subjects with symptomatic ICA stenosis admitted to a private secondary hospital in Jakarta, Indonesia, from January to December 2022. Symptoms were categorized to stroke/TIA and non-hemispheric symptoms (vertigo, headache, presyncope, etc.). Properties of CAS were recorded using digital subtraction angiography report. Brain abnormalities were recorded using MRI report.
Results: Brain MRI abnormalities were detected in 96.2% CAS cases and similar between stroke (96.2%) and non-hemispheric symptoms (96.0%). The abnormalities tended to be in bilateral hemisphere (61.0%), predominantly periventricle (41.9%), basal ganglia (26.1%), and internal capsule for mild CAS (16.8%). Ipsilateral brain lesions were significantly associated with severe CAS (20.9% versus 10.8% for non-ipsilateral brain lesion, p=0.042) and stroke (45.9% versus 24.0% in non-hemispheric symptoms, p=0.035). Non-ipsilateral brain lesions were significantly associated with mild CAS (49.6% versus 40.7% for ipsilateral brain lesion, p=0.042) and non-hemispheric symptoms (72.0% versus 50.3% in stroke, p=0.035).
Conclusions: Brain MRI abnormalities were very prevalent in CAS. There were no specific markers of brain MRI abnormalities associated with CAS. Brain abnormalities had been found since mild CAS, which presented in bilateral hemisphere as non-hemispheric symptoms. This study underlines the importance for the assessment of CAS in subjects since non-hemispheric symptoms with brain ischemic-related pathologies.