bluuebunny/crossref_metadata_2025 huggingface dataset:
Kinematic features in patients with lateral discoid meniscus injury during walking
Authors: Lin Zefeng , Huang Wenhan , Ma Limin , Chen Lingling , Huang Zhiqiang , Zeng Xiaolong , Xia Hong , Zhang Yu
Published: March 2018

At present, there few studies on the kinematic features of lateral discoid meniscus injury. In this study, a motion capture system was used to investigate the motion characteristics of knees with lateral discoid meniscus after injury, and the differences between the knees with lateral meniscus and intact knees were compared. Fourteen patients diagnosed with unilateral lateral discoid meniscus injury, fourteen patients diagnosed with unilateral lateral meniscus injury, and fourteen normal subjects with healthy knees were recruited and grouped. Through kinematic gait analysis, it was found that the subjects in the two groups with meniscus injuries exhibited significantly smaller ranges of rotation and translation than those with healthy knees on the sagittal, coronal, and horizontal planes, but not in proximal-distal translation. Maximum lateral tibial translation and maximum internal tibial rotation in the knees with lateral discoid meniscus injury were significantly decreased compared to those with lateral meniscus injury. The results show that the kinematic features of knees with lateral discoid meniscus injury are statistically different than those of healthy knees and knees with lateral meniscus injury. This study provides an important reference for the dynamic function of knees with lateral discoid meniscus injury.
Electrospinning over Solvent Casting: Tuning of Mechanical Properties of Membranes
Authors: Ghosal Kajal , Chandra Aniruddha , G. Praveen , S. Snigdha , Roy Sudeep , Agatemor Christian , Thomas Sabu , Provaznik Ivo
Published: March 2018

We put forth our opinion regarding the enhanced plasticity and modulation of mechanical properties of polymeric films obtained through electrospinning process in this article. In majority of the pharmaceutical, biomedical, and packaging applications, it is desirable that polymer based matrices should be soft, flexible, and have a moderate toughness. In order to convert inflexible and brittle polymers, adjuvants in the form of plasticizers are added to improve the flexibility and smoothness of solvent casted polymer films. However, many of these plasticizers are under scrutiny for their toxic effects and environmental hazards. In addition, plasticizers also increase the cost of end products. This has motivated the scientific community to investigate alternate approaches. The changes imparted in membrane casted by electrospinning were tried to be proved by SEM, Mechanical property study, DSC and XRD studies. We have showed dramatic improvement in flexibility of poly(ε-caprolactone) based nanofiber matrix prepared by electrospinning method whereas solvent casting method without any plasticizer produced very brittle, inflexible film of PCL. Modulation capacity of mechanical properties is also recorded. We tried to support our opinion by citing several similar findings available in the open literature. The electrospinning method helps in plasticization and in tuning mechanical properties.
A multi-scale approach to describe electrical impulses propagating along actin filaments in both intracellular andin vitroconditions
Authors: Hunley Christian , Uribe Diego , Marucho Marcelo
Published: March 2018

An innovative analytic solution accounting for the molecular structure, its biological environment, and their impact on electrical impulses along microfilaments.
Scalable and cost-effective Ag nanowires flexible transparent electrodes
Authors: He W. W. , Yan X. H. , Liang Y. M. , Long Y. F. , Pan C. , Zhao J. L. , Chen L. , Xiong W. , Liu Q. X.
Published: March 2018

This paper reports one of a scalable, cost effective Ag nanowires (AgNWs) TE, which reveals a significant reduction of four orders in magnitude of sheet resistance, from 90 kΩ sq−1 to 12 Ω sq−1, while keep transmittance of about 92% at 550 nm.
Delivery of modified mRNA encoding vesicular stomatitis virus matrix protein for colon cancer gene therapy
Authors: Men Ke , Zhang Rui , Zhang Xueyan , Huang Rong , Zhu Guonian , Tong Rongsheng , Yang Li , Wei Yuquan , Duan Xingmei
Published: March 2018

Liposome–protamine complex delivered VSVMP mRNA efficiently inhibits C26 colon carcinoma with safety, providing an alternative strategy for non-viral gene therapy.
Nano-engineering of a 3D-ordered membrane electrode assembly with ultrathin Pt skin on open-walled PdCo nanotube arrays for fuel cells
Authors: Zeng Yachao , Zhang Hongjie , Wang Zhiqiang , Jia Jia , Miao Shu , Song Wei , Xiao Yu , Yu Hongmei , Shao Zhigang , Yi Baolian
Published: March 2018

A 3D-ordered MEA with ultralow Pt loading and ultrahigh durability has been designed and constructed for PEMFCs.
Development of a portable sensor to evaluate copper speciation in natural waters
Authors: Urban R. C. , Romero J. R. , Campos M. L. A. M.
Published: March 2018

The proposed new sensor combines low cost, sensitivity, selectivity, portability and suitability for the speciation analysis of copper in natural waters.
Efficient catalysts for oxygen evolution derived from cobalt-based alloy nanochains
Authors: Yuan Xiaotao , Wang Xin , Riaz Muhammad Sohail , Dong Chenlong , Zhang Zhe , Huang Fuqiang
Published: March 2018

One-dimensional nanomaterials are widely used in electrocatalysis owing to their high charge transfer efficiency.
Solvent-free synthesis of monodisperse Cu nanoparticles by thermal decomposition of an oleylamine-coordinated Cu oxalate complex
Authors: Togashi Takanari , Nakayama Masato , Hashimoto Atsuki , Ishizaki Manabu , Kanaizuka Katsuhiko , Kurihara Masato
Published: March 2018

Monodisperse Cu nanoparticles are synthesized via the thermal decomposition of an oleylamine-coordinated Cu oxalate complex in high yield (∼90%).
Ionothermal synthesis of discrete supertetrahedral Tn(n= 4, 5) clusters with tunable components, band gaps, and fluorescence properties
Authors: Yang Dan-Dan , Li Wei , Xiong Wei-Wei , Li Jian-Rong , Huang Xiao-Ying
Published: March 2018

A series of discrete supertetrahedral Tn(n= 4, 5) clusters have been ionothermally synthesized.
Unsymmetrical diborane(4) derivatives by copper mediated B–B coupling
Authors: Oschmann W. , Borner C. , Kleeberg C.
Published: March 2018

Seven examples of novel unsymmetrical sp2–sp2diborane(4) derivatives by copper mediated B–B coupling.
A novel low-thermal-budget approach for the co-production of ethylene and hydrogenviathe electrochemical non-oxidative deprotonation of ethane
Authors: Ding Dong , Zhang Yunya , Wu Wei , Chen Dongchang , Liu Meilin , He Ting
Published: March 2018

A novel non-oxidative approach to convert ethane into ethylene and pure hydrogen electrochemically at 400 °C with low-thermal-budget and low-carbon-footprint.
Quantum anomalous Hall effect in a stable 1T-YN2monolayer with a large nontrivial bandgap and a high Chern number
Authors: Kong Xiangru , Li Linyang , Leenaerts Ortwin , Wang Weiyang , Liu Xiong-Jun , Peeters François M.
Published: March 2018

Three chiral edge states related to a high Chern number.
Degradation of Si/Ge core/shell nanowire heterostructures during lithiation and delithiation at 0.8 and 20 A g−1
Authors: Kim Dongheun , Li Nan , Sheehan Chris J. , Yoo Jinkyoung
Published: March 2018

The charging rate-dependent degradation of lithium ion battery anodes based on Si/Ge core/shell nanowire heterostructure was observed. Si/Ge core/shell structure was preserved at the charging rate of 0.8 A g−1. On the other hand, compositional intermixing and loss of Si occurs at the charging rate of 20 A g−1.
Direct synthesis of alkenyl iodidesviaindium-catalyzed iodoalkylation of alkynes with alcohols and aqueous HI
Authors: Wu Chao , Wang Zheng , Hu Zhan , Zeng Fei , Zhang Xing-Yu , Cao Zhong , Tang Zilong , He Wei-Min , Xu Xin-Hua
Published: March 2018

A simple and efficient method has been developed for the synthesis of alkenyl iodides through indium-catalyzed iodoalkylation of alkynes with alcohols and aqueous HI under mild conditions.
Stereoselective synthesis of N-ethyl-2-arylvinyl-5-methyl fulleropyrrolidines: reaction of [60]fullerene with aromatic aldehydes and triethylamine/diethylamine in the absence or presence of manganese(iii) acetate
Authors: Zhang Meng , Wang Hui-Juan , Li Fa-Bao , Zhong Xin-Xin , Huang Yongshun , Liu Li , Liu Chao-Yang , Asiri Abdullah M. , Alamry Khalid A.
Published: March 2018

Reaction of [60]fullerene with aromatic aldehydes and triethylamine/diethylamine afforded a series of novel fulleropyrrolidines.
Studies of La- and Pr-driven reverse distortion of FeO6 octahedral structure, magnetic properties and hyperfine interaction of BiFeO3 powder
Authors: Xiao RenZheng , Hu Tao , Yuan XianBao , Zhou JianJun , Ma XiaoQiang , Fu DeJun
Published: March 2018

Mössbauer spectra of the Bi1−x−yLaxPryFeO3 (x = 0 and 0.05; y = 0, 0.10, 0.15 and 0.20) (BLPFO) powders.
Eco-friendly synthesis of graphene–chitosan composite hydrogel as efficient adsorbent for Congo red
Authors: Omidi Sakineh , Kakanejadifard Ali
Published: March 2018

Graphene/chitosan-based hydrogel was synthesized using glutaraldehyde as crosslinking agent in room temperature and it used for removal of Congo red dye from aqueous solution.
Bio-inspired self-assembly of waxberry-like core-shell SiO2@TiO2 nanoparticles towards antiglare coatings
Authors: Yu Mingli , Sun Aihua , Chu Chengyi , Chen Tao , Yu Chengbing , Wang Biao , Guo Jianjun , Xu Gaojie
Published: March 2018

The dip-coating self-assembly of waxberry-like core–shell SiO2@TiO2 nanoparticles has been used to fabricate antiglare coatings with excellent antiglare properties in the large angle and wide wavelength range.
Bedaquiline has potential for targeting tuberculosis reservoirs in the central nervous system
Authors: Pamreddy Annapurna , Baijnath Sooraj , Naicker Tricia , Ntshangase Sphamandla , Mdanda Sipho , Lubanyana Hlengekile , Kruger Hendrik G. , Govender Thavendran
Published: March 2018

Bedaquiline (BDQ) was administered to healthy Sprague-Dawley rats in order to determine its localisation in the brain using mass spectrometry imaging (MSI). This study shows that BDQ has the potential for targeting TB reservoirs in the CNS.
Chemical metabolomics for investigating the protective effectiveness ofAcanthopanax senticosusHarms leaf against acute promyelocytic leukemia
Authors: Han Yue , Zhang Ai-Hua , Zhang Ying-Zhi , Sun Hui , Meng Xiang-Cai , Wang Xi-Jun
Published: March 2018

We have used chemical metabolomics to investigate and discover small molecule metabolites for the potential mechanism ofAcanthopanax senticosusHarms leaf (ASL) against acute promyelocytic leukemia (APL).
A distal vinyl shift (DVS) through quadruple domino reaction: synthesis of N-vinyl benzoheterocyclic scaffolds
Authors: Bakthadoss Manickam , Mushaf Mohammad
Published: March 2018

An unprecedented Distal Vinyl Shift (DVS) through quadruple domino reaction has been disclosed via the synthesis of N-vinyl benzoheterocyclic scaffolds.
Melamine as a single source for fabrication of mesoscopic 3D composites of N-doped carbon nanotubes on graphene
Authors: Yan Xiao-Ling , Li Hua-Fei , Wang Chen , Jiang Bang-Bang , Hu Hai-Yan , Xie Ning , Wu Marvin H. , Vinodgopal K. , Dai Gui-Ping
Published: March 2018

Integration of two-dimensional graphene and one-dimensional carbon nanotubes (CNTs) to create potentially useful 3D mesoscopic carbon structures with enhanced properties relative to the original materials is very desirable.
High-temperature thermoelectric properties of Na- and W-Doped Ca3Co4O9 system
Authors: Hira Uzma , Han Li , Norrman Kion , Christensen Dennis Valbjørn , Pryds Nini , Sher Falak
Published: March 2018

The detailed crystal structures and high temperature thermoelectric properties of polycrystalline Ca3−2xNa2xCo4−xWxO9 (0 ≤ x ≤ 0.075) samples have been investigated.
Using knowledge space theory to compare expected and real knowledge spaces in learning stoichiometry
Authors: Segedinac M. T. , Horvat S. , Rodić D. D. , Rončević T. N. , Savić G.
Published: March 2018

This paper proposes a novel application of knowledge space theory for identifying discrepancies between the knowledge structure that experts expect students to have and the real knowledge structure that students demonstrate on tests. The proposed approach combines two methods of constructing knowledge spaces. The expected knowledge space is constructed by analysing the problem-solving process, while the real knowledge space is identified by applying a data-analytic method. These two knowledge spaces are compared for graph difference and the discrepancies between the two are analysed. In this paper, the proposed approach is applied to the domain of stoichiometry. Although there was a decent agreement between expected and real knowledge spaces, a number of relations that were not present in the expected one appeared in the real knowledge space. The obtained results led to a general conclusion for teaching stoichiometry and pointed to some potential improvements in the existing methods for evaluating cognitive complexity.
Titanium carbide-decorated graphite felt as high performance negative electrode in vanadium redox flow batteries
Authors: Ghimire Purna C. , Schweiss Rüdiger , Scherer Günther G. , Wai Nyunt , Lim Tuti M. , Bhattarai Arjun , Nguyen Tam D. , Yan Qingyu
Published: March 2018

Binder free titanium carbide decorated graphite felt as high performance negative electrode in vanadium redox flow battery.
Novel safer phosphonate-based gel polymer electrolytes for sodium-ion batteries with excellent cycling performance
Authors: Zheng Jinyun , Zhao Yanhong , Feng Xiangming , Chen Weihua , Zhao Yufen
Published: March 2018

Phosphonate containing GPEs for safer sodium ion batteries with high capacity and stable long term cycling performance.
Phosphorene oxides as a promising cathode material for sealed non-aqueous Li–oxygen batteries
Authors: Li Yan , Ma Fei , Wang Lin-Wang
Published: March 2018

A fully sealed Li–O battery based on a phosphorene oxide cathode is demonstrated with high specific capacity, energy density and anisotropic diffusivity.
Quantum capacitance of CuS:Ce3+ quantum dots as high-performing supercapacitor electrodes
Authors: Chuai Mingyan , Yang Tianye , Zhang Mingzhe
Published: March 2018

The supercapacitor has the energy density of 129.87 W h kg−1 at a power density of 15584.4 W kg−1 and an energy density of 107.32 W h kg−1 at a power density of 32196.1 W kg−1.
Influence of hole transport layers on internal absorption, charge recombination and collection in HC(NH2)2PbI3 perovskite solar cells
Authors: Liu Yang , Zhang Hao , Zhang Yuping , Xu Bin , Liu Leijing , Chen Gang , Im Chan , Tian Wenjing
Published: March 2018

The internal absorption, charge recombination and collection in HC(NH2)2PbI3 (FAPbI3) perovskite solar cells with P3HT and spiro-OMeTAD as the HTL are investigated. The results show that the HTL can affect the internal absorption spectra of the perovskite layers, and spiro-OMeTAD HTL is beneficial for reducing the recombination and enhancing the charge collection in PeSCs.
A bottom-up synthetic hierarchical buffer structure of copper silicon nanowire hybrids as ultra-stable and high-rate lithium-ion battery anodes
Authors: Song Hucheng , Wang Sheng , Song Xiaoying , Yang Huafeng , Du Gaohui , Yu Linwei , Xu Jun , He Ping , Zhou Haoshen , Chen Kunji
Published: March 2018

Silicon (Si) is a promising anode material for next-generation high-energy lithium-ion batteries (LIBs).
Ag-Hybridized plasmonic Au-triangular nanoplates: highly sensitive photoacoustic/Raman evaluation and improved antibacterial/photothermal combination therapy
Authors: Peng Ya , Liu Yu , Lu Xiaolin , Wang Shouju , Chen Maomao , Huang Wenchao , Wu Zhiyou , Lu Guangming , Nie Liming
Published: March 2018

Core–shell metal nanostructures with versatile functions have attracted extensive attention and are highly desirable for imaging and therapeutic purposes.
Pd2Se3monolayer: a novel two-dimensional material with excellent electronic, transport, and optical properties
Authors: Zhu Xiaorong , Li Feng , Wang Yu , Qiao Man , Li Yafei
Published: March 2018

The experimentally realized Pd2Se3monolayer has excellent electronics, transport, and optical properties.
Atorvastatin ameliorates early brain injury through inhibition of apoptosis and ER stress in a rat model of subarachnoid hemorrhage
Authors: Qi Wentao , Cao Demao , Li Yucheng , Peng Aijun , Wang Youwei , Gao Kai , Tao Cunshan , Wu Yongkang
Published: March 2018

Aneurysmal subarachnoid hemorrhage (SAH) is a severe cerebrovascular disease with very poor prognosis. The aim of the present study was to evaluate the protective effects of atorvastatin on early brain injury (EBI) after SAH using a perforation SAH model. Male Sprague–Dawley rats were randomly divided into four groups: the sham group, the SAH group (model group), SAH + 10 mg.kg−1.day−1 atorvastatin (low atorvastatin group), and SAH + 20 mg.kg−1.day−1 atorvastatin (high atorvastatin group). Atorvastatin was administered orally by gastric gavage for 15 days before operation. At 24 h after SAH, we evaluated the effects of atorvastatin on brain water content, apoptosis by TUNEL assay and scanning electron microscope (SEM), and the expression of apoptosis-related proteins by immunofluorescence and Western blotting analysis. Compared with the sham group, we observed increased brain water content, significant apoptosis, and elevated levels of apoptosis-related proteins including caspase-3, CCAAT enhancer-binding protein homologous protein (CHOP), the 78-kDa glucose-regulated protein (GRP78), and aquaporin-4 (AQP4) in the SAH group. Atorvastatin administration under all doses could significantly reduce brain water content, apoptosis, and the expression levels of caspase-3, CHOP, GRP78, and AQP4 at 24 h after SAH. Our data show that early treatment with atorvastatin effectively ameliorates EBI after SAH through anti-apoptotic effects and the effects might be associated inhibition of caspase-3 and endoplasmic reticulum (ER) stress related proteins CHOP and GRP78.
The Effect of Partner Reauditorization on Undergraduates' Attitudes Toward a Peer Who Communicates With Augmentative and Alternative Communication
Authors: Hyppa-Martin Jolene , Reichle Joe
Published: March 2018

Purpose

This study compared college students' attitudes toward a peer who used a nonelectronic augmentative and alternative communication (AAC) system with and without a partner reauditorization strategy and also examined the effect of reauditorization on reported (a) ease of understanding the peer who used AAC, (b) willingness to engage in interactions with the peer who used AAC, and (c) preferences regarding AAC systems.

Method

Sixty-four participants completed surveys after viewing each of 2 counterbalanced conditions involving a video of a peer who communicated using AAC. Mean survey ratings were compared between conditions.

Results

Participants reported (a) more positive attitudes toward, (b) a greater ease in understanding, and (c) an increased willingness to interact with the peer who used nonelectronic AAC with partner reauditorization. Participants indicated that reauditorization contributed positively to the observed conversation. Reported preferences for nonelectronic AAC systems did not vary as a function of reauditorization, and most participants reported a preference for an electronic speech-generating device when compared with a nonelectronic system.

Conclusion

Partner reauditorization may play a role in improving attitudes that individuals hold about peers who use nonelectronic AAC and may contribute to ease of understanding the aided message and increased likelihood of peer interactions.
Comparison of Subjective and Objective Measures of Hearing, Auditory Processing, and Cognition Among Older Adults With and Without Mild Cognitive Impairment
Authors: Fausto Bernadette A. , Badana Adrian N. S. , Arnold Michelle L. , Lister Jennifer J. , Edwards Jerri D.
Published: March 2018

Purpose

The aims of the study were to compare the Cognitive Self-Report Questionnaire (CSRQ; Spina, Ruff, & Mahncke, 2006) Hearing and Cognitive subscale ratings among older adults with and without probable mild cognitive impairment (MCI) and to examine whether self-report, as measured by the CSRQ, is associated with objective measures of hearing, auditory processing, and cognition.

Method

Data analyses included 97 older adults of ages 61–91 years. Participants completed the CSRQ self-report measure as well as a battery of objective measures, including pure-tone audiometry, degraded speech understanding, temporal processing, and memory.

Results

Older adults with probable MCI rated their cognitive abilities more poorly than those without MCI (
p
= .002), but ratings of hearing and auditory abilities did not differ between the two groups (
p
= .912). Age and CSRQ Hearing subscale ratings explained a significant proportion of variance in objective measures of hearing and degraded speech understanding (
R
2
= .39,
p
< .001). Age, sex, mental status, and CSRQ Cognition subscale ratings explained a significant proportion of variance in objective memory performance (
R
2
= .55,
p
< .001).

Conclusions

Taken together, these results suggest that the CSRQ is an appropriate self-report measure of hearing, cognition, and some aspects of auditory processing for older adults with and without probable MCI.
Two‐dimensional frequency decoupling method for curved trajectory synthetic aperture radar imaging
Authors: Wu Junjie , An Hongyang , Zhang Qianghui , Sun Zhichao , Li Zhongyu , Du Ke , Huang Yulin , Yang Jianyu
Published: March 2018

Synthetic aperture radar (SAR) imaging with curved trajectory is difficult due to its severe two‐dimensional (2D) space variance. When processing the echo with azimuth‐variance, the range cell migration and Doppler modulation of the targets with different azimuth locations are different, which brings a big challenge to image formation. Here, a 2D frequency decoupling method for this case is proposed. Firstly, the range history of the curved trajectory is accurately modelled based on fourth‐order Taylor series expansion. Then, the 2D point target reference spectrum of the echo signal is obtained by the method of series reversion. The 2D space variance characteristics of two typical cases with curved trajectory, i.e. geosynchronous SAR and missile‐borne SAR, are analysed. Based on the space variance characteristics, a 2D frequency decoupling step is implemented to handle the space‐variant phase. Simulations are presented to demonstrate the effectiveness of the proposed algorithm.
Effect of external periodic signals and electromagnetic radiation on autaptic regulation of neuronal firing
Authors: Ge Mengyan , Xu Ying , Lu Lulu , Zhao Yunjie , Yang Lijian , Zhan Xuan , Gao Kaifu , Li Anbang , Jia Ya
Published: March 2018

An improved Hindmarsh–Rose (HR) neuron model, where the memristor is a bridge between membrane potential and magnetic flux, can be used to investigate the effect of periodic signals on autaptic regulation of neurons under electromagnetic radiation. Based on the improved HR model driven by periodic high–low‐frequency current and electromagnetic radiation, the responses of electrical autaptic regulation with diverse high–low‐frequency signals are investigated using bifurcation analysis. It is found that the electrical modes of neurons are determined by the selecting parameters of both periodic high and low‐frequency current and electromagnetic radiation, and the Hamiltonian energy depends on the neuronal firing modes. The effects of Gaussian white noise on the membrane potential are discussed using numerical simulations. It is demonstrated that external high–low‐frequency stimulus plays a significant role in the autaptic regulation of neural firing mode, and the electrical mode of neurons can be affected by the angular frequency of both high–low‐frequency forcing current and electromagnetic radiation. The mechanism of neuronal firing regulated by high–low‐frequency signal and electromagnetic radiation discussed here could be applied to research neuronal networks and synchronisation modes.
Gravitational wave driven mergers and coalescence time of supermassive black holes
Authors: Khan Fazeel Mahmood , Berczik Peter , Just Andreas
Published: March 2018

Aims. The evolution of supermassive black holes (SMBHs) initially embedded in the centres of merging galaxies realised with a stellar mass function (SMF) is studied from the onset of galaxy mergers until coalescence. Coalescence times of SMBH binaries are of great importance for black hole evolution and gravitational wave detection studies.

Methods. We performed direct N-body simulations using the highly efficient and massively parallel phi-GRAPE+GPU code capable of running on high-performance computer clusters supported by graphic processing units (GPUs). Post-Newtonian terms up to order 3.5 are used to drive the SMBH binary evolution in the relativistic regime. We performed a large set of simulations with three different slopes of the central stellar cusp and different random seeds. The impact of a SMF on the hardening rate and the coalescence time is investigated.

Results. We find that SMBH binaries coalesce well within one billion years when our models are scaled to galaxies with a steep cusp at low redshift. Here higher central densities provide a larger supply of stars to efficiently extract energy from the SMBH binary orbit and shrink it to the phase where gravitational wave (GW) emission becomes dominant, leading to the coalescence of the SMBHs. Mergers of models with shallow cusps that are representative of giant elliptical galaxies having central cores result in less efficient extraction of the binary’s orbital energy, due to the lower stellar densities in the centre. However, high values of eccentricity witnessed for SMBH binaries in such galaxy mergers ensure that the GW emission dominated phase sets in earlier at larger values of the semi-major axis. This helps to compensate for the less efficient energy extraction during the phase dominated by stellar encounters resulting in mergers of SMBHs in about 1 Gyr after the formation of the binary. Additionally, we witness mass segregation in the merger remnant resulting in enhanced SMBH binary hardening rates. We show that at least the final phase of the merger in cuspy low-mass galaxies would be observable with the GW detector eLISA.
Constraining physical conditions for the PDR of Trumpler 14 in the Carina Nebula
Authors: Wu Ronin , Bron Emeric , Onaka Takashi , Le Petit Franck , Galliano Frédéric , Languignon David , Nakamura Tomohiko , Okada Yoko
Published: March 2018

We investigate the physical conditions of the CO gas, based on the submillimeter imaging spectroscopy from a 2′ × 7′ (1.5 × 5 pc2) area near the young star cluster, Trumpler 14 of the Carina Nebula. The observations presented in this work are taken with the Fourier Transform Spectrometer (FTS) of the Spectral and Photometric Imaging REceiver (SPIRE) onboard the Herschel Space Observatory. The newly observed spectral lines include [CI] 370 μm [CI] 609 μm, and CO transitions from J = 4−3 to J = 13−12. Our field of view covers the edge of a cavity carved by Trumpler 14 about 1 Myr ago and marks the transition from H ii regions to photo-dissociation regions. The observed CO intensities are the most prominent at the northwest region, Car I-E. With the state-of-the-art Meudon PDR code, we successfully derive the physical conditions, which include the thermal pressure (P) and the scaling factor of radiation fields (GUV), from the observed CO spectral line energy distributions (SLEDs) in the observed region. The derived GUV values generally show excellent agreement with the UV radiation fields created by nearby OB-stars and thus confirm that the main excitation source of the observed CO emission is the UV-photons provided by the massive stars. The derived thermal pressure is in the range 0.5−3 × 108 K cm-3 with the highest values found along the ionization front in Car I-E region facing Trumpler 14, hinting that the cloud structure is similar to the recent observations of the Orion Bar. We also note a discrepancy at a local position (<0.17 × 0.17 pc2) between the photo-dissociation region (PDR) modeling result and the UV radiation fields estimated from nearby massive stars, which requires further investigation on nearby objects that could contribute to local heating, including outflow. Comparing the derived thermal pressure with the radiation fields, we report the first observationally derived and spatially resolved P ~ 2 × 104 GUV relationship. As direct comparisons of the modeling results to the observed 13CO, [O I] 63 μm, and [C II] 158 μm intensities are not straightforward, we urge the reader to be cautious when constraining the physical conditions of PDRs with combinations of 12CO, 13CO, [C I], [O I] 63 μm, and [C II] 158 μm observations.
Multi-wavelength campaign on NGC 7469
Authors: Mehdipour M. , Kaastra J. S. , Costantini E. , Behar E. , Kriss G. A. , Bianchi S. , Branduardi-Raymont G. , Cappi M. , Ebrero J. , Di Gesu L. , Kaspi S. , Mao J. , De Marco B. , Middei R. , Peretz U. , Petrucci P.-O. , Ponti G. , Ursini F.
Published: March 2018

We investigate the physical structure of the active galactic nucleus (AGN) wind in the Seyfert-1 galaxy NGC 7469 through high-resolution X-ray spectroscopy with Chandra HETGS and photoionisation modelling. Contemporaneous data from Chandra, HST, and Swift are used to model the optical-UV-X-ray continuum and determine the spectral energy distribution (SED) at two epochs, 13 yr apart. For our investigation we use new observations taken in December 2015–January 2016, and historical ones taken in December 2002. We study the impact of a change in the SED shape, seen between the two epochs, on the photoionisation of the wind. The HETGS spectroscopy shows that the AGN wind in NGC 7469 consists of four ionisation components, with their outflow velocities ranging from − 400 to − 1800 km s-1. From our modelling we find that the change in the ionising continuum shape between the two epochs results in some variation in the ionisation state of the wind components. However, for the main ions detected in X-rays, the sum of their column densities over all components remains in practice unchanged. For two of the four components, which are found to be thermally unstable in both epochs, we obtain 2 < r < 31 pc and 12 < r < 29 pc using the cooling and recombination timescales. For the other two thermally stable components, we obtain r < 31 pc and r < 80 pc from the recombination timescale. The results of our photoionisation modelling and thermal stability analysis suggest that the absorber components in NGC 7469 are consistent with being a thermally driven wind from the AGN torus. Finally, from analysis of the zeroth-order ACIS/HETG data, we discover that the X-ray emission in the range 0.2–1 keV is spatially extended over 1.5–12′′. This diffuse soft X-ray emission is explained by coronal emission from the nuclear starburst ring in NGC 7469. The star formation rate inferred from this diffuse soft X-ray emission is consistent with those found by far-infrared studies of NGC 7469.
The coordinated radio and infrared survey for high-mass star formation
Authors: Kalcheva I. E. , Hoare M. G. , Urquhart J. S. , Kurtz S. , Lumsden S. L. , Purcell C. R. , Zijlstra A. A.
Published: March 2018

A catalogue of 239 ultra-compact H II  regions (UCHIIs) found in the CORNISH survey at 5 GHz and 1.5″ resolution in the region 10° < l < 65°,  |b| < 1° is presented. This is the largest complete and well-selected sample of UCHIIs to date and provides the opportunity to explore the global and individual properties of this key state in massive star formation at multiple wavelengths. The nature of the candidates was validated, based on observational properties and calculated spectral indices, and the analysis is presented in this work. The physical sizes, luminosities and other physical properties were computed by utilising literature distances or calculating the distances whenever a value was not available. The near- and mid-infrared extended source fluxes were measured and the extinctions towards the UCHIIs were computed. The new results were combined with available data at longer wavelengths and the spectral energy distributions (SEDs) were reconstructed for 177 UCHIIs. The bolometric luminosities obtained from SED fitting are presented. By comparing the radio flux densities to previous observational epochs, we find about 5% of the sources appear to be time variable. This first high-resolution area survey of the Galactic plane shows that the total number of UCHIIs in the Galaxy is ~750 – a factor of 3–4 fewer than found in previous large area radio surveys. It will form the basis for future tests of models of massive star formation.
Color study of asteroid families within the MOVIS catalog
Authors: Morate David , Licandro Javier , Popescu Marcel , de León Julia
Published: March 2018

The aim of this work is to study the compositional diversity of asteroid families based on their near-infrared colors, using the data within the MOVIS catalog. As of 2017, this catalog presents data for 53 436 asteroids observed in at least two near-infrared filters (Y,J,H, orKs). Among these asteroids, we find information for 6299 belonging to collisional families with bothY−JandJ−Kscolors defined. The work presented here complements the data from SDSS and NEOWISE, and allows a detailed description of the overall composition of asteroid families. We derived a near-infrared parameter, theML*, that allows us to distinguish between four generic compositions: two different primitive groups (P1 and P2), a rocky population, and basaltic asteroids. We conducted statistical tests comparing the families in the MOVIS catalog with the theoretical distributions derived from ourML*in order to classify them according to the above-mentioned groups. We also studied the background populations in order to check how similar they are to their associated families. Finally, we used this parameter in combination with NEOWISE and SDSS to check for possible bimodalities in the data. We found 43 families withML*err< 0.071 and with at least 8 asteroids observed: 5 classified as P1, 10 classified as P2, 19 families associated with the rocky population, and 9 families that were not linked to any of the previous populations. In these cases, we compared our samples with different combinations of these theoretical distributions to find the one that best fits the family data. We also show, using the data from MOVIS and NEOWISE, that the Bapistina family presents a two-cluster distribution in the near-infrared albedo vs.ML*parameter space that might be related to a common differentiated parent body. Finally, we show that the backgrounds we defined seem to be linked to their associated families.
Coronal hole evolution from multi-viewpoint data as input for a STEREO solar wind speed persistence model
Authors: Temmer Manuela , Hinterreiter Jürgen , Reiss Martin A.
Published: March 2018

We present a concept study of a solar wind forecasting method for Earth, based on persistence modeling from STEREO in situ measurements combined with multi-viewpoint EUV observational data. By comparing the fractional areas of coronal holes (CHs) extracted from EUV data of STEREO and SoHO/SDO, we perform an uncertainty assessment derived from changes in the CHs and apply those changes to the predicted solar wind speed profile at 1 AU. We evaluate the method for the time period 2008–2012, and compare the results to a persistence model based on ACE in situ measurements and to the STEREO persistence model without implementing the information on CH evolution. Compared to an ACE based persistence model, the performance of the STEREO persistence model which takes into account the evolution of CHs, is able to increase the number of correctly predicted high-speed streams by about 12%, and to decrease the number of missed streams by about 23%, and the number of false alarms by about 19%. However, the added information on CH evolution is not able to deliver more accurate speed values for the forecast than using the STEREO persistence model without CH information which performs better than an ACE based persistence model. Investigating the CH evolution between STEREO and Earth view for varying separation angles over ∼25–140° East of Earth, we derive some relation between expanding CHs and increasing solar wind speed, but a less clear relation for decaying CHs and decreasing solar wind speed. This fact most likely prevents the method from making more precise forecasts. The obtained results support a future L5 mission and show the importance and valuable contribution using multi-viewpoint data.
Factors involved in the clinical profile of carpal tunnel syndrome
Authors: Puchalski Piotr , Zyluk Paulina , Szlosser Zbigniew , Zyluk Andrzej
Published: March 2018

Clinical presentation of carpal tunnel syndrome may differ in relation to certain factors like sex, age, duration of symptoms and severity of compression. The
objective of this study was an investigation into the hypothesis that several distinct factors are predictive of the clinical profile for the condition. The
records of 1,117 patients: 909 women (81 %) and 208 men (19 %) with a mean age of 63 years, were analysed. The whole group was divided into subgroups, depending
on the variables analysed: sex, age, duration of the condition, severity of symptoms, severity of electrophysiological abnormalities and occurrence or lack of
comorbidities. Results. Of all the considered variables, the Levine symptom scores had the greatest impact on the condition’s clinical profile: the higher
scores the more severe pain, poorer sensation, weaker grip and worse hand function. Also, ages greater than 80 years had a significant negative effect on most
of the considered parameters. None of the remaining analysed variables had a substantial impact on the clinical profile of the condition.
Osteitis fibrosa cystica an der Hand: eine seltene, aber wichtige Differentialdiagnose
Authors: Spicher Rüdiger , Patzelt Thomas , Bauer Hans-Joachim
Published: March 2018

Einleitung

Der primäre Hyperparathyreodismus ist die zweithäufigste Knochenstoffwechselerkrankung (25–28 auf 100 000/Jahr) nach der Osteoporose 1. In ca. 80 % der Fälle liegt ursächlich ein Nebenschilddrüsenadenom zugrunde. Erhöhte Parathormon-Titer führen durch Osteoklastenaktivierung zu
Hypercalci- und Hypophosphatämie 2. Undiagnostiziert und unbehandelt kann es neben vielfältigen anderen Symptomen (z. B.
Nierensteine, Magenulcera) zu überschießenden Knochenresorptionen mit Ausbildung von Knochentumoren (sog. „braune Tumoren“) kommen. Diese betreffen gerade auch die
Hand und können die Stabilität gefährden. Für die Erkrankung existieren verschiedene Synonyme, so u. a. „Osteodystrophia fibrosa“ oder im englischen Sprachraum
„von-Recklinghausen`s disease of bone“.
Safety of lumen-apposing stent with or without coaxial plastic stent for endoscopic ultrasound-guided drainage of pancreatic fluid collections: a retrospective study
Authors: Puga Manuel , Consiglieri Claudia , Busquets Juli , Pallarès Natàlia , Secanella Lluis , Peláez Nuria , Fabregat Joan , Castellote José , Gornals Joan
Published: March 2018

Background The aim of this study was to evaluate whether the placement of a coaxial double-pigtail plastic stent (DPS) within a lumen-apposing metal stent (LAMS) may improve the safety of endoscopic ultrasound (EUS)-guided drainage of pancreatic fluid collections (PFCs).

Methods This was a retrospective cohort study including patients with PFCs and an indication for transmural drainage. Two strategies (LAMS alone or LAMS plus DPS) were used at the endoscopist’s discretion.

Results A total of 41 patients were treated (21 LAMS alone; 20 LAMS plus DPS). The characteristics of the PFCs, and the technical and clinical success rates did not differ between groups. The LAMS alone group had a significantly higher rate of adverse events than the LAMS plus DPS group (42.9 % vs. 10.0 %; P = 0.04). Bleeding was the most frequent adverse event observed.

Conclusions The addition of a coaxial DPS to LAMS was associated with a lower rate of adverse events in EUS-guided drainage of PFCs.
Stereoselective Allylation of Linear and Chiral β-Amino-α-Hydroxy Aldehydes: Total Syntheses of Tetraacetyl d-lyxo-, d-ribo-, and
d-arabino-Phytosphingosines
Authors: Myeong In-Soo , Kim Jin-Seok , Park Muyng-Gyu , Jeon Hwan-Hee , Jung Changyoung , Lee Yong-Taek , Ham Won-Hun
Published: March 2018

The stereoselective allylations of β-amino-α-hydroxy aldehydes­ are described. Several Lewis acids (BF3·OEt2, SnCl4, TiCl4, ZnCl2­, and MgBr2·OEt2) were utilized in the allylations. The allylation of anti-β-NHCbz-α-OTBS substrate mediated by SnCl4 afforded the syn-selective­ product, while its allylation mediated by BF3·OEt2 afforded the anti-selective product. The allylation of syn-β-NHCbz-α-OTBS mediated by SnCl4 afforded the anti-selective product. The mechanism involves the chelation between the amido group and aldehyde oxygen by SnCl4, and the Felkin–Anh model by BF3·OEt2. The resulting allylation products were used for the total syntheses of tetraacetyl d-lyxo-, d-ribo-, and d-arabino-phytosphingosines.
Epidemiological Profile of Intracerebral Hemorrhage during a 10-Year Period in a Southern Brazilian Region
Authors: Almeida Timóteo , Almeida Fernanda , Giacomini Luidia , Niederauer Andressa , Cho Anna , Mallmann Adroaldo , Camelo Ricardo , Bertolin Telma
Published: March 2018

Objective Spontaneous intracerebral hemorrhage is responsible for 20% of all cases of cerebrovascular accidents, which might lead to functional disabilities and death. There are few epidemiological data on spontaneous intracerebral hemorrhage in Brazil, and more specifically in the southern region of the country.

Methods We reviewed data of 221 patients with intracerebral hemorrhage who attended our department between January of 2004 and December of 2013 and were registered as I61 and I62 according to the 10th edition of the International Classification of Diseases and Related Health Problems (ICD-10).

Results From the 221 cases, 53.8% were male, and the median age was 63 years old. Arterial hypertension was reported in 62.4% of the patients. Surgical treatment was performed in 28.9% of all cases and pneumonia affected 19.9%. In 73.4% of the cases, the patients died or were severely disabled at discharge. We found an association of heart disease, coagulopathies, chronic kidney disease, anticoagulant drugs use, surgical treatment, and pneumonia with a poorer outcome.

Conclusion The present study describes the epidemiological profile of intracerebral hemorrhage in a southern Brazilian population during a 10-year period.
CT-ADP Point-of-Care Assay Predicts 30-Day Paravalvular Aortic Regurgitation and Bleeding Events following Transcatheter Aortic Valve Replacement
Authors: Kibler Marion , Marchandot Benjamin , Messas Nathan , Caspar Thibault , Vincent Flavien , Von Hunolstein Jean-Jacques , Grunebaum Lelia , Reydel Antje , Rauch Antoine , Crimizade Ulun , Kindo Michel , Hoang Minh Tam , Trinh Annie , Petit-Eisenmann Hélène , De Poli Fabien , Leddet Pierre , Jesel Laurence , Ohlmann Patrick , Susen Sophie , Van Belle Eric , Morel Olivier
Published: March 2018

Background Paravalvular aortic regurgitation (PVAR) remains a frequent postprocedural concern following transcatheter aortic valve replacement (TAVR). Persistence of flow turbulence results in the cleavage of high-molecular-weight von Willebrand multimers, primary haemostasis dysfunction and may favour bleedings. Recent data have emphasized the value of a point-of-care measure of von Willebrand factor–dependent platelet function (closure time [CT] adenosine diphosphate [ADP]) in the monitoring of immediate PVAR. This study examined whether CT-ADP could detect PVAR at 30 days and bleeding complications following TAVR.

Methods CT-ADP was assessed at baseline and the day after the procedure. At 30 days, significant PVAR was defined as a circumferential extent of regurgitation more than 10% by transthoracic echocardiography. Events at follow-up were assessed according to the Valve Academic Research Consortium-2 consensus classification.

Results Significant PVAR was diagnosed in 44 out of 219 patients (20.1%). Important reduction of CT-ADP could be found in patients without PVAR, contrasting with the lack of CT-ADP improvement in significant PVAR patients. By multivariate analysis, CT-ADP > 180 seconds (hazard ratio [HR]: 5.1, 95% confidence interval [CI]: 2.5–10.6; p < 0.001) and a self-expandable valve were the sole independent predictors of 30-day PVAR. At follow-up, postprocedural CT-ADP >180 seconds was identified as an independent predictor of major/life-threatening bleeding (HR: 1.7, 95% CI [1.0–3.1]; p = 0.049). Major/life-threatening bleedings were at their highest levels in patients with postprocedural CT-ADP > 180 seconds (35.2 vs. 18.8%; p = 0.013).

Conclusion Postprocedural CT-ADP > 180 seconds is an independent predictor of significant PVAR 30 days after TAVR and may independently contribute to major/life-threatening bleedings.
Different Manifestations of Rare Cases of Unruptured Sinus of Valsalva Aneurysm—Case Series and Literature Review
Authors: Pandit Bhagya Narayan , Subramaniyan Siva , Kumar Tarun , Agrawal Richa , Vatsa Deepankar
Published: March 2018

Sinus of Valsalva aneurysm (SVA) is rare, and aneurysm of the left sinus of Valsalva is extremely rare cardiovascular disease. Clinical presentation can vary from mostly asymptomatic to catastrophic life-threatening emergency. We report four extremely rare cases of SVA with different manifestations of which one case involved left aortic sinus with large unruptured aneurysm causing severe mitral regurgitation (MR) and severe aortic regurgitation (AR). The second case aneurysm was from right sinus presented with trifascicular block with intermittent complete heart block (CHB). Third was a diagnosed case of unruptured right SVA and while awaiting for surgery he had sudden cardiac death (SCD) at home. Therefore, SVA can present from asymptomatic to life-threatening condition, such as SCD. To the best of our knowledge, there are individual case reports in literature, and this is the first case series of unruptured SVA in literature highlighting the rarity of this disease.
Bildgebung in der Schwangerschaft
Authors: Loose Reinhard , Wucherer Michael
Published: March 2018

Es gibt immer wieder klinische Situationen, in denen die radiologische Bildgebung während der Schwangerschaft unumgänglich ist. Typische Beispiele sind internistische oder chirurgische Notfälle, insbesondere Unfälle. Bei einer streng gestellten, rechtfertigenden Indikation unter Einbeziehung von Ultraschall und MRT als Alternativen ist bei den meisten Untersuchungen das Risiko der Strahlenanwendung gegenüber dem Nutzen zu vernachlässigen.