bluuebunny/crossref_metadata_2025 huggingface dataset:
“The Philosophy of Social Darwinism...It has not Become Obsolete”: A Conservative Critique of Liberal “Social Darwnism”
Authors: Razuvalova Anna
Published: October 2021

This article looks into the conceptual and rhetorical repertoire of conservative critique directed against social Darwinism. Having borrowed the ideologically and emotionally charged concept of social Darwinism from the vocabulary of Soviet propaganda, Russian conservatives actively used it in order to conceptualize the political and economic reforms of the 1990s and their consequences. According to the author, the idea of a Malthusian substrate of classical social-darwinism, which was adopted from the Marxist tradtion by conservatives and allowed to bring social Darwinism closer to the ideology of the free market, was placed into new contexts around the turn of the 1990s and 2000s. These contexts were, on the one hand, conditioned by the fall of the USSR and, on the other hand, by the processes of globalization. The article shows how the critique of contemporary social Darwinism becomes the language for discussing global and local inequality, also influencing the traumatic mode of the conservative narrative about the “1990s disaster” on the one hand and the populist conservative rhetoric of the 2000s and the 2010s on the other.
The Place of Slavophilism in the Typology of Conservatism
Authors: Teslya Andrey
Published: October 2021

In the history of political thought, Russian Slavophilism of the period from 1840s till 1880s has two established traditions of interpretation: as a variant of conservative ideology and as one form of Russian liberalism of the 1840s, along with Westernism (in this case, the later history of Slavophilism, i.e. the period between 1860s and 1880s, is viewed as a departure from initially liberal stances. Beginning with the framework of Andrzej Walicki, the article attempts to demonstrate the underpinnings of this peculiar duality of evaluations. Slavophilism is understood as liberal conservatism; the article also uncovers the structural conditions, on which the liberal component of Slavophile views are based. Special attention is given to the analysis of processes, which led to the dominance of the interpretation, according to which Russian Slavophilism is a conservative ideology, where the liberal component is defined as situational. The reason for such a reading are rooted in the peculiar position of Russian liberalism in the late XIX century, when the nationalism agenda was interpreted as entirely pertaining to the conservative side of the political spectrum.
Thinking the Political with Jean-Luc Nancy
Authors: Mihkelsaar Janar
Published: October 2021

In this article, I argue that at the center of Jean-Luc Nancy’s approach to the political lies the thinking of subject as that of relation. Throughout the historical actualizations of, for example, the individual, the state, or the people as a subject, the problematic of relation is one that has retreated and now demands to be subjected to a retreatment. When the arche-teleological presuppositions that constitute subject as that which is given enter the phase of deconstruction, subject comes to present itself as nothing but the activity of relating itself to itself. I respond to Nancy’s call to invent “an affirmation of relation” by way of rethinking the logics of sovereignty and democracy. While sovereignty unites, posits, finitizes, and finishes the self of the people, a post-68 democracy pluralizes, infinitizes, and disfigures the identity of the people. Between sovereignty and democracy, notwithstanding their conflicting tenets, the relation is not that of reciprocal exclusion. One is rather the correlative of the other. Without the one, the other would not make any sense. Through this Janus-faced economy of the political, the people can experience its own “reality”—to experience relation itself. The affirmation of relation is what gives and keeps free the voided site of the political for the infinite self-institution of the people, and for that reason is political par excellence.
DNA Vaccines
Authors: Ulmer Jeffrey B
Published: October 2021

DNA vaccines were first discovered more than 30 years ago.

Because DNA vaccines result in antigen production in situ (i.e., mimic a virus infection), they elicit broad-based immune responses, including antibodies and T cells.

Induction of protective immunity has been established in scores of animal models of infectious and non-infectious diseases.

Hundreds of human clinical trials have been conducted demonstrating safety and, in many cases, antigen-specific immune responses.

Several animal health vaccines based on DNA have been approved and are in use.

Many DNA vaccines are in various stages of human clinical testing, including a few in phase 3 efficacy trials and the recent Emergency Use Authorization of a COVID-19 vaccine, but to date no DNA vaccines have been fully licensed for human use.

DNA vaccines are thermostable and amenable to large-scale manufacturing at relatively low cost, hence well-suited for global use, particularly in the developing world.

If potency in humans could be achieved, DNA vaccines would have the potential to be a radical innovation that could disrupt the vaccine industry.
Comparison of hematological markers between testicular torsion and epididymo-orchitis in acute scrotum cases
Authors: Benlioğlu Can , Çift Ali
Published: October 2021

Objective: In this study, we aimed to investigate the benefit of hematological results in determining the differential diagnosis between testicular torsion (TT) and epididymo-orchitis (EO) in patients presenting with acute scrotum, and to determine its predictive value for the diagnosis of TT. Material and Methods: We retrospectively analyzed 98 patients who applied to our institute’s urology clinics or emergency service with complaints of acute scrotum. Thirty-two patients who underwent orchiectomy or detorsion due to TT and 48 patients with EO were included in the study. The control group consisted of 80 healthy men. Groups were compared in terms of hematological parameters such as age, white blood cell (WBC), mean platelet volume (MPV), neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and platelet/lymphocyte ratio (PLR). Results: WBC, MPV and NLR were found to be statistically significant in distinguishing TT group from other groups, respectively; (AUC = 0.732, 95% CI: 0.647-0.816 and p<0.001), (AUC = 0.720, 95% CI: 0.615-0.825 and p<0.001), (AUC = 0.629, 95% CI: 0.519-0.739 and p=0.024). In the comparison between the detorsion and orchiectomy subgroups within the TT group, the first had a statistically lower monocyte count (p=0.005) and MLR level (p=0.038). Conclusion: Hematological parameters; that is, WBC, MPV and NLR, which can be easily determined from complete blood count analysis, had high sensitivity and specificity similar to Doppler ultrasonography to predict TT. In addition, we think that monocyte and MLR levels may be beneficial in patients who have difficulty in the decision of orchiectomy or detorsion in TT surgery. Keywords: Acute scrotum, testicular torsion, epididymo-orchitis, mean platelet volume, neutrophil/lymphocyte ratio
Clinical and pathological analysis of cases with graft nephrectomy after renal transplantation
Authors: Sevmiş Murat , Hacısalihoğlu Uğuray Payam
Published: October 2021

Objective: The number of cases with graft failure, which is the most frequent complication of renal transplantation, is increasing due to the increasing number of kidney transplant surgeries. Graft nephrectomy is the last treatment option in renal transplant recipients with graft failure due to the high complication risk it entails. The aim of the present study is to evaluate the clinical characteristics, etiologies for nephrectomy, pathological analysis of explanted graft, and surgical complications in recipients with graft nephrectomy. Material and Methods: We retrospectively analyzed 38 recipients who had undergone graft nephrectomy for different reasons in the center since 2010. The recipients were divided into two groups, according to the time of surgery, with characteristics analyzed retrospectively. The early graft nephrectomy group consisted of patients who had undergone graft nephrectomy in the first 6 months after transplant surgery; the late graft nephrectomy group consisted of patients who had undergone graft nephrectomy more than 6 months after surgery. Results: Indications for early graft nephrectomy were mostly vascular, surgical problems, and infection, whereas indications for late graft nephrectomy were rejection and infection. There was a statistically significant difference between the two groups with respect to rejection. The rate of graft survival, post-operative vascular and surgical complications were higher in the early group (p=0.011, and p=0.005, respectively). Panel Reactive Antibody (PRA) positivity was evaluated, and no difference was observed between the two groups in terms of immunological risk. Conclusions: As graft nephrectomy has high morbidity and mortality rates, it should only be applied in selected cases, where necessary, in order to prevent potentially serious complications. Keywords: Graft, nephrectomy, kidney, transplantation, renal, complications
ОСОБЛИВОСТІ ПРАВОВОГО СТАТУСУ ПОМІЧНИКА СУДДІ В АДМІНІСТРАТИВНОМУ І ЦИВІЛЬНОМУ СУДОЧИНСТВІ
Authors: Куценко К. Д.
Published: October 2021

Стаття присвячена особливостям правового статусу помічника судді в Україні. Проаналізовано норми законодавства, які встановлюють окремі аспекти правового статусу помічника судді, закріплені в законодавчих та підзаконних актах, процесуальних кодексах. Встановлено специфіку призначення та звільнення з посади помічника судді, його повноваження, вимоги до кандидатів на посаду помічника судді, особливості патронатної служби помічників суддів. З’ясовано специфіку взаємовідносин помічників суддів із працівниками апарату суду та громадянами. Запропоновано шляхи вдосконалення законодавства, яке регулює правовий статус помічника судді.
Development of Decision Support System for Early Stage Diabetes Diagnosis Using Machine Learning and Deep Learning Methods: A Comprehensive Analysis
Authors: Gurkan Caglar , Kozalioglu Sude , Palandoken Merih
Published: October 2021

Yaygın olarak görülen hastalıklardan biri olan diyabetin prevalansı her yıl artmaktadır. Diyabet hastalığı erken teşhis edilmezse kalp ve damar hastalıklarına, böbrek hastalığına, körlüğe, sinir hasarlarına, felce ve organ yetmezliklerine neden olabilir. Ayrıca bu diyabet hastaları için yapılacak sağlık harcamalarının da 2040 yılında 802 milyon dolar olacağı tahmin edilmektedir. Bu durumlar göz önünde bulundurulduğunda diyabet tanısı için yapılacak çalışmalar oldukça önemlidir. Bu çalışmada, diyabet tanısı için bir karar destek sistemi geliştirmek amacıyla karar ağaçları, k-en yakın komşu, lojistik regresyon, Naive Bayes, rastgele orman, destek vektör makineleri gibi makine öğrenmesi ve çok katmanlı algılayıcı (ÇKA), evrişimli sinir ağları (ESA), tekrarlayan sinir ağları (RNN) tasarımları olan Basit RNN, Uzun Kısa Dönem Bellek Ağları (LSTM), Geçitli Tekrarlayan Birim (GRU), İki Yönlü Uzun Kısa Dönem Bellek Ağları (BiLSTM), İki Yönlü Geçitli Tekrarlayan Birim (BiGRU), ESA ve RNN hibrit modelleri olan ESA+Simple RNN, ESA+LSTM, ESA+GRU, ESA+BiLSTM ve ESA+BiGRU gibi derin öğrenme yöntemleri kullanılmıştır. Makine öğrenmesi tabanlı sınıflandırıcılar içerisinde en yüksek sınıflandırma performansını %98.10 doğruluk oranı ve %98.00 F1- skoru ile DVM elde etmiştir. Derin öğrenme tabanlı sınıflandırıcılar içerisinde en yüksek sınıflandırma performansını %99.50 doğruluk oranı ve %99.30 F1- skoru ile ESA+BiGRU hibrit modeli elde etmiştir. Genel analizde ise, derin öğrenme tabanlı sınıflandırıcıların makine öğrenmesi tabanlı sınıflandırıcılara göre daha iyi performans göstermiştir. Ek olarak CNN ve RNN tasarımlarının hibrit modelleri, yalın modellere göre daha iyi sınıflandırma performansına sahiptir.
Volcanic Structures and Magmatic Evolution of the Vesteris Seamount, Greenland Basin
Authors: Unger Moreno Katharina A. , Thal Janis , Bach Wolfgang , Beier Christoph , Haase Karsten M.
Published: October 2021

The formation of isolated seamounts distant from active plate boundaries and mantle plumes remains unsolved. The solitary intraplate volcano Vesteris Seamount is located in the Central Greenland Basin and rises ∼3,000 m above the seafloor with a total eruptive volume of ∼800 km3. Here, we present a new high-resolution bathymetry of Vesteris Seamount and a detailed raster terrain analysis, distinguishing cones, irregular volcanic ridges, volcanic debris fans, U-shaped channels and lava flows. The slope angles, ruggedness index and slope direction were combined with backscatter images to aid geologic interpretation. The new data show that the entire structure is a northeast to southwest elongated stellar-shaped seamount with an elongated, narrow summit surrounded by irregular volcanic ridges, separated by volcanic debris fans. Whole-rock geochemical data of 78 lava samples form tight liquid lines of descent with MgO concentrations ranging from 12.6 to 0.1 wt%, implying that all lavas evolved from a similar parental magma composition. Video footage from Remotely Operated Vehicle (ROV) dives shows abundant pyroclastic and hyaloclastite deposits on the summit and on the upper flanks, whereas lavas are restricted to flank cones. The seamount likely formed above a weak zone of the lithosphere possibly related to initial rifting parallel to the nearby Mohns Ridge, but the local stress field increasingly affected the structure of the volcano as it grew larger. Thus, we conclude that the evolution of Vesteris Seamount reflects the transition from deep, regional lithospheric stresses in the older structures to shallower, local stresses within the younger volcanic structures similar to other oceanic intraplate volcanoes. Our study shows how the combination of bathymetric, visual and geochemical data can be used to decipher the geological evolution of oceanic intraplate volcanoes.
The Emerging Roles and Therapeutic Potential of Extracellular Vesicles in Infertility
Authors: Zhou Guannan , Gu Yuanyuan , Zhou Fangyue , Zhang Menglei , Zhang Ganrong , Wu Ligang , Hua Keqin , Ding Jingxin
Published: October 2021

Infertility is becoming much more common and affects more couples. The past years witnessed the rapid development of the diagnosis and treatment upon infertility, which give numerous coupled more opportunities become parents. Extracellular vesicles are known as nano-sized membrane vesicles to play a major role in intracellular communication. In recent years, several basic and clinical studies have tried to investigate the correlation between the reproductive health/disorder and extracellular vesicles. However, the mechanism is still unclear. In this review, we reviewed the relationship between reproductive physiology and extracellular vesicles, and then collectively focused on the recent findings on the relationship between extracellular and infertility, and its consequent influence on the novel insight regarding the therapeutic strategies for infertility in the future clinical practice.
Achieving Chinese Carbon Neutrality Based on Water–Temperature–Radiation–Land Coupling Use
Authors: Tian Yinglin , Xie Di , Li Tiejian , Li Jiaye , Zhang Yu , Jing Huan , Zhong Deyu , Wang Guangqian
Published: October 2021

Facing irreversible and catastrophic changes on the earth, China has committed to peak the net carbon emission by 2030 and to achieve carbon neutrality by 2060. The pledge requires significant mitigation immediately and sustainably. Considering this background, some perspectives are given in this article based on the comprehensive use of natural resources. First, utilizing the STIRPAT (stochastic impacts by regression on population, affluence, and technology) model and statistical data, net carbon emissions of provinces in China are anticipated, which lays a foundation for the further “three-step” carbon neutralization route. Second, a strategy of water–temperature–radiation–land coupling use is proposed, considering 1) the carbon emission cut, which relies on comparing the energy intensity and energy structure in China with those in developed countries; 2) the carbon sink increase, which depends on the evaluation of constraints of hydrometeorological factors on ecological productivity. Finally, the necessity and possibility of carbon trading and redistribution of the natural resources are discussed to ensure that China's national net carbon emission would be reduced to zero by 2060.
An Information-Entropy Position-Weighted K-Mer Relative Measure for Whole Genome Phylogeny Reconstruction
Authors: Wu Yao-Qun , Yu Zu-Guo , Tang Run-Bin , Han Guo-Sheng , Anh Vo V.
Published: October 2021

Alignment methods have faced disadvantages in sequence comparison and phylogeny reconstruction due to their high computational costs in handling time and space complexity. On the other hand, alignment-free methods incur low computational costs and have recently gained popularity in the field of bioinformatics. Here we propose a new alignment-free method for phylogenetic tree reconstruction based on whole genome sequences. A key component is a measure called information-entropy position-weighted k-mer relative measure (IEPWRMkmer), which combines the position-weighted measure of k-mers proposed by our group and the information entropy of frequency of k-mers. The Manhattan distance is used to calculate the pairwise distance between species. Finally, we use the Neighbor-Joining method to construct the phylogenetic tree. To evaluate the performance of this method, we perform phylogenetic analysis on two datasets used by other researchers. The results demonstrate that the IEPWRMkmer method is efficient and reliable. The source codes of our method are provided at https://github.com/ wuyaoqun37/IEPWRMkmer.
Combination of Pseudo-LC-NMR and HRMS/MS-Based Molecular Networking for the Rapid Identification of Antimicrobial Metabolites From Fusarium petroliphilum
Authors: Alfattani Abdulelah , Marcourt Laurence , Hofstetter Valérie , Queiroz Emerson Ferreira , Leoni Sara , Allard Pierre-Marie , Gindro Katia , Stien Didier , Perron Karl , Wolfender Jean-Luc
Published: October 2021

An endophytic fungal strain isolated from a seagrass endemic to the Mediterranean Sea (Posidonia oceanica) was studied in order to identify its antimicrobial constituents and further characterize the composition of its metabolome. It was identified as Fusarium petroliphilum by in-depth phylogenetic analyses. The ethyl acetate extract of that strain exhibited antimicrobial activities and an ability to inhibit quorum sensing of Staphylococcus aureus. To perform this study with a few tens of mg of extract, an innovative one-step generic strategy was devised. On one side, the extract was analyzed by UHPLC-HRMS/MS molecular networking for dereplication. On the other side, semi-preparative HPLC using a similar gradient profile was used for a single-step high-resolution fractionation. All fractions were systematically profiled by 1H-NMR. The data were assembled into a 2D contour map, which we call “pseudo-LC-NMR,” and combined with those of UHPLC-HRMS/MS. This further highlighted the connection within structurally related compounds, facilitated data interpretation, and provided an unbiased quantitative profiling of the main extract constituents. This innovative strategy led to an unambiguous characterization of all major specialized metabolites of that extract and to the localization of its bioactive compounds. Altogether, this approach identified 22 compounds, 13 of them being new natural products and six being inhibitors of the quorum sensing mechanism of S. aureus and Pseudomonas aeruginosa. Minor analogues were also identified by annotation propagation through the corresponding HRMS/MS molecular network, which enabled a consistent annotation of 27 additional metabolites. This approach was designed to be generic and applicable to natural extracts of the same polarity range.
Chemically Synthesized Alcaligenes Lipid A as an Adjuvant to Augment Immune Responses to Haemophilus Influenzae Type B Conjugate Vaccine
Authors: Liu Zilai , Hosomi Koji , Shimoyama Atsushi , Yoshii Ken , Sun Xiao , Lan Huangwenxian , Wang Yunru , Yamaura Haruki , Kenneth Davie , Saika Azusa , Nagatake Takahiro , Kiyono Hiroshi , Fukase Koichi , Kunisawa Jun
Published: October 2021

We previously identified Alcaligenes spp. as a commensal bacterium that resides in lymphoid tissues, including Peyer’s patches. We found that Alcaligenes-derived lipopolysaccharide acted as a weak agonist of Toll-like receptor four due to the unique structure of lipid A, which lies in the core of lipopolysaccharide. This feature allowed the use of chemically synthesized Alcaligenes lipid A as a safe synthetic vaccine adjuvant that induces Th17 polarization to enhance systemic IgG and respiratory IgA responses to T-cell–dependent antigens (e.g., ovalbumin and pneumococcal surface protein A) without excessive inflammation. Here, we examined the adjuvant activity of Alcaligenes lipid A on a Haemophilus influenzae B conjugate vaccine that contains capsular polysaccharide polyribosyl ribitol phosphate (PRP), a T-cell–independent antigen, conjugated with the T-cell–dependent tetanus toxoid (TT) antigen (i.e., PRP-TT). When mice were subcutaneously immunized with PRP alone or mixed with TT, Alcaligenes lipid A did not affect PRP-specific IgG production. In contrast, PRP-specific serum IgG responses were enhanced when mice were immunized with PRP-TT, but these responses were impaired in similarly immunized T-cell—deficient nude mice. Furthermore, TT-specific—but not PRP-specific—T-cell activation occurred in mice immunized with PRP-TT together with Alcaligenes lipid A. In addition, coculture with Alcaligenes lipid A promoted significant proliferation of and enhanced antibody production by B cells. Together, these findings suggest that Alcaligenes lipid A exerts an adjuvant activity on thymus-independent Hib polysaccharide antigen in the presence of a T-cell–dependent conjugate carrier antigen.
Exercise in the Park or Gym? The Physiological and Mental Responses of Obese People Walking in Different Settings at Different Speeds: A Parallel Group Randomized Trial
Authors: Wang Xinxin , Zhou Quanfu , Zhang Mingjuan , Zhang Qinghai
Published: October 2021

Evidence shows that physical activity has multiple health benefits for the body and mind of oneself, but little is known about the impacts of the setting and the intensity on exercise experience, especially for obese people. This study investigated the physiological and psychological effects of four walking conditions with different settings (park vs. gym) and intensity (slow vs. fast) on young obese adults. Subjects were 18–21 years old Chinese university students (N = 77), who were diagnosed as obese. They were randomly assigned to participate in one of the four activities in the field: slow walk in the park (2.8 km/h), fast walk in the park (5.5 km/h), slow walk in the gym, and fast walk in the gym. Physiological indices, including blood pressure and heart rate, were measured before and after the walk. Psychological responses were measured by the Symbol Digit Modalities Test, the mood states scale, and the semantic differential scale. This study of obese people aged 18–21 years confirmed the previous findings that exercising in natural environments better relieved stress and restored attentional level than indoor activities. The results suggested that the mood states of the participants and their environmental perceptions may be influenced by the walking conditions with different setting and speed. The findings can be used in planning and designing urban green spaces for promoting physical activity and making exercise plans for obese people.
Emotion Recognition of Chinese Paintings at the Thirteenth National Exhibition of Fines Arts in China Based on Advanced Affective Computing
Authors: Li Jing , Chen Dongliang , Yu Ning , Zhao Ziping , Lv Zhihan
Published: October 2021

Today, with the rapid development of economic level, people’s esthetic requirements are also rising, they have a deeper emotional understanding of art, and the voice of their traditional art and culture is becoming higher. The study expects to explore the performance of advanced affective computing in the recognition and analysis of emotional features of Chinese paintings at the 13th National Exhibition of Fines Arts. Aiming at the problem of “semantic gap” in the emotion recognition task of images such as traditional Chinese painting, the study selects the AlexNet algorithm based on convolutional neural network (CNN), and further improves the AlexNet algorithm. Meanwhile, the study adds chi square test to solve the problems of data redundancy and noise in various modes such as Chinese painting. Moreover, the study designs a multimodal emotion recognition model of Chinese painting based on improved AlexNet neural network and chi square test. Finally, the performance of the model is verified by simulation with Chinese painting in the 13th National Exhibition of Fines Arts as the data source. The proposed algorithm is compared with Long Short-Term Memory (LSTM), CNN, Recurrent Neural Network (RNN), AlexNet, and Deep Neural Network (DNN) algorithms from the training set and test set, respectively, The emotion recognition accuracy of the proposed algorithm reaches 92.23 and 97.11% in the training set and test set, respectively, the training time is stable at about 54.97 s, and the test time is stable at about 23.74 s. In addition, the analysis of the acceleration efficiency of each algorithm shows that the improved AlexNet algorithm is suitable for processing a large amount of brain image data, and the acceleration ratio is also higher than other algorithms. And the efficiency in the test set scenario is slightly better than that in the training set scenario. On the premise of ensuring the error, the multimodal emotion recognition model of Chinese painting can achieve high accuracy and obvious acceleration effect. More importantly, the emotion recognition and analysis effect of traditional Chinese painting is the best, which can provide an experimental basis for the digital understanding and management of emotion of quintessence.
Buffering – Please Be Patient! Does the Attribution of Pauses to Technical Issues Hamper Learning?
Authors: Merkt Martin
Published: October 2021

In educational contexts, system-determined pauses are often used to interrupt the transient flow of information and thus avoid cognitive overload in dynamic learning materials. However, next to these didactically motivated interruptions, video-based learning materials may also be interrupted due to technical issues with regard to constrained bandwidth or outdated technology. Against this background, the current experiment investigated whether the interruption of dynamic representations due to technical issues negatively affects learning. For this purpose, 64 participants watched an Arabic language tutorial. They were either informed that the video included breaks in order to support learning or that there may be breaks due to technical issues. Contrary to our pre-registered hypotheses, the attribution of the pauses to technical issues did not hamper learning and did not affect participants' ratings regarding the usefulness and the disturbance caused by the pauses. However, exploratory analyses revealed a negative correlation between the perceived usefulness and the disturbance caused by the pauses. Limitations and implications of these findings are discussed.
Can Sport Concussion Assessment Tool (SCAT) Symptom Scores Be Converted to Rivermead Post-concussion Symptoms Questionnaire (RPQ) Scores and Vice Versa? Findings From the Toronto Concussion Study
Authors: Langer Laura Kathleen , Comper Paul , Ruttan Lesley , Saverino Cristina , Alavinia Seyed Mohammad , Inness Elizabeth L. , Kam Alice , Lawrence David W. , Tam Alan , Chandra Tharshini , Foster Evan , Bayley Mark T.
Published: October 2021

Background: The Rivermead Post-Concussion Symptoms Questionnaire (RPQ) and the Sports Concussion Assessment Tool (SCAT) are widely used self-report tools assessing the type, number, and severity of concussion symptoms. There are overlapping symptoms and domains, though they are scored differently. The SCAT consists of 22 questions with a 7-point Likert scale for a total possible score 132. The RPQ has 16 questions and a 5-point Likert scale for a total of 64 possible points. Being able to convert between the two scores would facilitate comparison of results in the concussion literature.

Objectives: To develop equations to convert scores on the SCAT to the RPQ and vice versa.

Methods: Adults (17–85 years) diagnosed with a concussion at a referring emergency department were seen in the Hull-Ellis Concussion and Research Clinic, a rapid access concussion clinic at Toronto Rehab–University Health Network (UHN) Toronto Canada, within 7 days of injury. The RPQ and SCAT symptom checklists as well as demographic questionnaires were administered to all participants at Weeks 1, 2, 3, 4, 5, 6, 7, 8, 12, 16.

Results: 215 participants had 1,168 matched RPQ and SCAT assessments. Total scores of the RPQ and the SCAT had a rho = 0.91 (p < 0.001); correlations were lower for sub-scores of specific symptom domains (range 0.74–0.87, p < 0.001 for all domain comparisons). An equation was derived to calculate SCAT scores using the number and severity of symptoms on the RPQ. Estimated scores were within 3 points of the observed total score on the SCAT. A second equation was derived to calculate the RPQ from the proportion weighted total score of the SCAT. This equation estimated corresponding scores within 3 points of the observed score on the RPQ.

Conclusions: The RPQ and SCAT symptom checklists total scores are highly correlated and can be used to estimate the total score on the corresponding assessment. The symptom subdomains are also strongly correlated between the 2 scales however not as strongly correlated as the total score. The equations will enable researchers and clinicians to quickly convert between the scales and to directly compare concussion research findings.
Embodied narratives: communicative value of tattoos
Authors: Czernecka Karolina
Published: October 2021

Since the ‘50s there is a steady rise in popularity and social acceptance towards tattooing. While people may choose to get a tattoo for a variety of reason, it seems that for the majority they are meaningful and convey personal messages and stories in symbolic form. This article focuses on communicative quality of tattoos, derived from their narrative design. First, the social meaning of the very fact of being tattooed is discussed, drawing on prevailing social prejudice and stereotypes. Then, tattoos are analyzed from the standpoint of personal narratives, showcasing various meanings that can be deciphered both by the others and by tattoees themselves. Finally, the dynamic and relative nature of tattoos is examined, with a closing reflection upon the reason why getting tattoos might be so compelling.
Mental resilience of adolescents entering adulthood during pandemic
Authors: Gaweł Anna , Ostafińska-Molik Barbara
Published: October 2021

Mental resilience is a relatively permanent trait of personality which enables a person to initiate adaptation processes by activating subjective resources. It helps maintain good functioning despite adversities, in difficult situations and in the face of troubles of everyday life. Development of resilience is influenced by individual factors and by factors related to the features of the family environment and the non-family social environment. The level of resilience influences the course of development in adolescence, and its shaping is a function of developmental processes.

The aim of the presented research was to determine the level of resilience of first-year students who experienced the negative effects of the Sars-Cov-2 virus pandemic in 2020 and to compare this level of resilience to the results of measurements carried out on groups of adolescents at the same stage of development in 2014 and 2016. The analyzes were based on the results of own studies conducted in 2016 and 2020 and on existing data published in 2014.

The Resilience Measurement Scale (SPP-25) (N. Ogińska-Bulik, Z. Juczyński) was used in each measurement. In the statistical analyzes the student’s t-test for one sample and the student’s t-test for independent samples were used.

The results indicate a statistically significant decrease in the intensity of resilience and its dimensions among the respondents surveyed in 2020 compared to the results obtained by their peers in 2014 and 2016. With regard to the results of standardization studies, the average overall resilience score among students who faced the negative effects of the pandemic was in the low range. The most significant decrease in the level of resilience was occurred in two dimensions:   “optimistic attitude to life and the ability to mobilize in difficult situations” and “personal coping skills and tolerance of negative emotions”. The decrease of the level of resilience in all its dimensions in the youth surveyed in 2020 is difficult to explain only by the negative effects of the experienced pandemic. The causes of the phenomenon should be sought in family and non-family conditions of the process of its formation in childhood and adolescence.
PCOS, Hashimoto's disease, celiac disease, endometriosis - genetically conditioned autoimmune disorder causing infertility?
Authors: Jankowska Katarzyna , Kaźmierczak-Dejewska Aleksandra
Published: October 2021

Infertility is a social problem today. The causes of infertility can be both on the side of the woman and on the side of the man. One of the most common causes of infertility in women is polycystic ovary syndrome (PCOS). It has been proven that it often coexists with autoimmune thyroiditis (AIT), i.e. with Hashimoto's disease. In many patients with PCOS and AIT, endometriosis and celiac disease are also found. It seems that these disorders: PCOS, AIT, endometriosis and celiac disease may have a common autoimmune basis. More and more patients with infertility or recurrent miscarriages have autoimmune problems. Probably a genetic predisposition is necessary to reveal the disease.
Environmental Ecology versus Human Ecology
Authors: Szpoton Szczepan
Published: October 2021

A collation of environmental ecology with human ecology was the essence of the article. The field of the research included the topics: blending the range of care for ecosystem with the responsibility for our own human nature; presenting a connection between sexuality and procreation concentrated on the gift of marital unity yet protecting the dignity of human procreation; pointing at the areas of human life where the “ecological conversion” takes place.
PENGARUH RADIASI ELEKTROMAGNETIK TERHADAP PERTUMBUHAN VEGETATIF TANAMAN TOMAT (Solanum lycopersicum L.)
Authors: Pratama Hilman Aditya , Amarullah Amarullah , Santoso Dwi
Published: October 2021

ABSTRACT There are several things that cause an increase in the yield of tomato plants, one of which is the application of electromagnetic radiation to plants, thus encouraging some researchers in agriculture to review whether electromagnetic radiation has a positive influence on the growth and production of tomato plants. Electromagnetic field treatment and frequency of exposure using 56 μT electromagnetic fields to determine the effect on tomato plant growth in the vegetative phase. This research was conducted in January 2017 until completion. In this study the tools used included: a series of electromagnetic inductors, batteries, pipes, aluminum foil, tomato plant media, while the ingredients used were servo varieties of tomato seeds that were first sown. The treatments in this study were P0 = control, P1 = application for 20 minutes, control, P2 = application for 40 minutes, control, P3 = application for 60 minutes, control, P4 = application for 80 minutes. The results showed that the observation parameters that showed statistically significantly different results were parameters of plant height, number of leaves and stem diameter, the best treatment for each observation parameter was P2 treatment (exposure to electromagnetic radiation for 40 minutes).Keywords : Electromagnetic Radiation, Tomato Plant, VegetatifABSTRAK Terdapat beberapa hal yang menyebabkan terjadinya peningkatkan hasil produksi tanaman tomat salah satunya adalah dengan pengaplikasian radiasi elektromagnetik terhadap tanaman, sehingga mendorong beberapa peneliti dibidang pertanian untuk meninjau apakah radiasi elektromagnetik memiliki pengaruh positif terhadap pertumbuhan dan produksi tanaman tomat. Perlakuan besar medan elektromagnetik serta frekuensi pemaparan dengan menggunakan 56 µT medan elektromagnetik untuk mengetahui pengaruh terhadap pertumbuhan tanaman tomat pada fase vegetatif. Penelitian ini dilaksanakan pada bulan Januari 2017 sampai dengan selesai. Dalam penelitian ini alat yang digunakan meliputi: rangkaian induktor elektromagnetik, aki, pipa, alimunium foil, media tanaman tomat, sedangkan bahan yang digunakan adalah benih tomat varietas servo yang terlebih dahulu disemai. Perlakuan pada penelitian ini P0= kontrol, P1= pengaplikasian selama 20 menit, kontrol, P2= pengaplikasian selama 40 menit, kontrol, P3= pengaplikasian selama 60 menit, kontrol, P4= pengaplikasian selama 80 menit. Hasil penelitian menunjukan bahwa parameter pengamatan yang menunjukan hasil berbeda nyata secara statistik adalah parameter tinggi tanaman, jumlah daun dan diameter batang, perlakuan terbaik untuk setiap parameter pengamatan adalah perlakuan P2 (pemaparan radiasi elektromagnetik selama 40 menit).Kata kunci : Radiasi elektromagnetik, Tanaman tomat , vegetatif
ANALISIS PENGENDALIAN PERSEDIAAN (CV. ARMID JAYA KOTA PANGKAJENE, KABUPATEN SIDRAP SULAWESI SELATAN)
Authors: Padapi Astrini , R Fitriani
Published: October 2021

ABSTRACT One company engaged in the development of agribusiness is CV. Armid Jaya. In practice CV. Armid Jaya also been overwhelmed. This study aims to analyse the stock control system in CV. Armid Jaya.A descriptive reseacrh was conducted using the EOQ method, focusing on the analysis of rice stock. It is a case study conducted at CV. Armid Jaya.The result reveal several things related to the use of EOQ method. Firstly, the total stock reached 569.508.354 rupiahs in 2015, 577.357.674 rupiah in 2016, and 688.490.499 rupiah in 2017. Secondly, the data about economic purchasing were 6.428 ton (in 2015),5.342 (in 2016), and 5.854 ton (in 2017); Thirdly, with the EOQ method, the company could save as much as 214.343.065 rupiahs in 2015,210.301.084 in 2016 and 270.269.068 in 2017. Futhermore, reserve stock reached 1,083 tons in 2015, 1,083 tonsin 2016 and 1,165 tons in 2017. Finally, the data about maximum grain stock were 2,983 tons (in 2015), 3,000 tons (in 2016), and 3,147 tons (in 2017). Key Words: Stock, Grain, EOQ ABSTRAK Masalah persediaan gabah yang tidak efisien dapat membuat CV. Armid Jaya perusahaan kewalahan dalam memenuhi permintaan konsumen. Penelitian ini bertujuan untuk dapat menganalisis dan mengetahui sistem pengendalian persediaan pada CV. Armid Jaya. Penelitian ini merupakan penelitian deskriptif dengan menggunakan metode EOQ. Fokus penelitian ini adalah menganalisis persediaan beras dengan studi kasus pada CV. Armid Jaya. Hasil penelitian menunjukkan bahwa dengan menggunakan metode EOQ terdapat beberapa hal terkait yaitu (1) total biaya persediaan yang ditanggung pada tahun 2015 Rp. 569.508.354, tahun 2016 sebesar Rp.577.357.674 dan tahun 2017 sebesar Rp. 688.490.499; (2) jumlah pembelian ekonomis pada tahun 2015 adalah 6.428 ton, tahun 2016 adalah 5.342 ton dan pada tahun 2017 yaitu sebesar 5.854 ton;(3) dengan menggunakan metode EOQ, tahun 2015 perusahaan dapat menghemat Rp.  214.343.065, pada tahun 2016, dapat menghemat Rp. 210.301.084 dan pada tahun 2017 perusahaan dapat menghemat  Rp. 270.269.068;(4) persediaan pengaman tahun 2015 sebesar  1,083 ton, tahun 2016 sebesar 1,083 ton dan pada tahun 2017 adalah sebesar 1,165,ton;(5) Persediaan gabah maksimum di tahun 2015 sebesar 2,983 ton, tahun 2016 adalah 3,000 ton dan tahun 2017 adalah 3,147 ton. Kata Kunci: Persediaan, Gabah, EOQ
KARAKTERISASI MORFOLOGI TANAMAN ENAU DI KENAGARIAN SUNGAI NANIANG
Authors: Wulantika Trisia
Published: October 2021

ABSTRACT Enau plant (Arenga pinnata Merr) is a type of palma plant that the entire plant can be utilized and potential to be developed. Sungai Naniang is the highest sugar producer in Bukik Barisan Sub-District, with an area of 20 ha. This research aims to find out the morphological characteristics of germplasm enau in Kenagarian Sungai Naniang.This research has been carried out in May to June 2018 with purposive sampling method. The results of the study found 4 variations of the stem color of the entire accession namely dark brown, light brown, grayish brown and grayish brown. The leaves of the enau plant are complete and compound leaves.Based on observations that have been made, there are not many variations in qualitative characters, otherwise many variations are found in quantitative characters. on the entire accession is black with a rough surface. Male flowers are like bullets, they sit in pairs and are purple. Round Female Flower, stand alone, green. Seeds are round in oval shape The number of seeds 3 per fruit and white. Keywords : Enau, Characterization, Morphology, Plant Breeding ABSTRAK Tanaman enau (Arenga pinnata Merr) adalah salah satu jenis tumbuhan palma yang Keseluruhan bagian tanamannya dapat dimanfaatkan dan potensial untuk dikembangkan. Kenagarian Sungai Naniang merupakan penghasil gula enau tertinggi di Kecamatan Bukik Barisan, dengan luasan mencapai 20 Ha. Penelitian ini bertujuan untuk mengetahui karakteristik morfologi plasma nutfah enau di Kenagarian Sungai Naniang.Penelitian ini telah dilaksanakan  pada bulan Mei sampai Juni 2018 dengan metode purposive sampling. Hasil penelitian ditemukan 4 variasi warna batang dari keseluruhan aksesi yaitu  berwarna cokelat gelap, cokelat terang, coklat keabu-abuan dan abu-abu.Daun tanaman enau merupakan daun lengkap dan majemuk.Berdasarkan pengamatan yang telah dilakukan, tidak banyak ditemukan variasi  pada  karakter  kualitatif,  sebaliknya  banyak  ditemukan  variasi  pada karakter kuantitatif. ijuk  pada  keseluruhan  aksesi  berwarna  hitam  dengan permukaan yang kasar. Bunga Jantan       Seperti peluru, duduknya berpasangan dan berwarna ungu. Bunga Betina           Bulat, berdiri sendiri, berwarna hijau. Biji  berbentuk  bulat  lonjong Jumlah biji 3 perbuah dan berwarna putih.Kata Kunci : Enau, Karakterisasi, Morfologi, Pemuliaan Tanaman
Uji Aktivitas Antijamur Ekstrak Biji Bligo (Benincasa hispida (Thunb.) Cogn.) terhadap Pertumbuhan Jamur Candida albicans
Authors: Luhurningtyas Fania Putri , Vifta Rissa Laila , Khotimah Siti Khusnul
Published: October 2021

Tanaman bligo (Benincasa hispida (Thunb.) Cogn.) merupakan tanaman yang termasuk di dalam famili Cucurbitae atau sejenis labu. Khasiat tradisional bligo secara turun menurun adalah sebagai laksatif, diuretik, dispepsia, dan anti inflamasi. Telah dilakukan uji aktivitas antijamur ekstrak etanol biji bligo terhadap Candida albicans untuk mengetahui aktivitas penghambatan pertumbuhan jamur dan identifikasi golongan metabolit sekundernya. Penelitian ini dilakukan beberapa tahap, yaitu ekstraksi senyawa bioaktif menggunakan refluks, skrining fitokimia dan uji aktivitas antijamur dengan metode mikrodilusi. Ekstrak etanol biji bligo mempunyai aktivitas antijamur yang lemah dengan nilai konsentrasi hambat minimum (MIC) sebesar 250 mg/mL dan konsentrasi bunuh minimum (MFC) sebesar        > 500 mg/mL. Hasil identifikasi metabolit sekunder menunjukkan ekstrak etanol biji bligo positif mengandung alkaloid, flavonoid, dan saponin.
Kesesuaian Obat Hipoglikemik Oral pada Pasien Diabetes Mellitus Tipe 2 di Fasilitas Kesehatan Tingkat Pertama X di Surakarta
Authors: Khusna Khotimatul , Septiana Rita
Published: October 2021

ABSTRAKDiabetes mellitus (DM) didefinisikan sebagai penyakit kronis yang disebabkan karena keturunan atau kurangnya produksi insulin oleh pankreas, atau tidak efektifnya insulin yang dihasilkan. Pelayanan obat untuk peserta Jaminan Kesehatan Nasional pada fasilitas kesehatan mengacu pada daftar obat yang tercantum dalam Formularium Nasional (Fornas). Selain itu, pelayanan kesehatan juga harus sesuai dengan algoritma terapi. Pemilihan obat hipoglikemik oral (OHO) yang tepat sangat menentukan keberhasilan terapi DM. Penelitian ini bertujuan untuk mengetahui gambaran kesesuaian penggunaan OHO berdasarkan Fornas dan algoritma terapi DM tipe 2 di Faskes Tingkat Pertama X di Surakarta. Penelitian ini termasuk jenis penelitian deskriptif. Pengambilan data dilakukan secara retrospektif dari catatan rekam medik pasien. Sampel dalam penelitian ini adalah OHO di Faskes Tingkat Pertama X di Surakarta pada periode Januari sampai Mei 2019. Hasil penelitian menunjukkan bahwa pasien yang mendapatkan OHO sesuai rekomendasi Fornas sebanyak 105 dan pasien yang mendapatkan OHO sesuai rekomendasi Algoritma Terapi DM sebanyak 75. Kesimpulan penelitian ini adalah 100% penggunaan OHO sesuai rekomendasi Fornas dan 71,43 % penggunaan OHO sesuai rekomendasi Algoritma Terapi DM.Kata kunci : Kesesuaian, Diabetes, Fornas, Algoritma terapiDiabetes mellitus (DM) is a chronic disease caused by heredity or when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. Medication services for National Health Insurance participants in health facilities refer to the list of drugs listed in the National Formulary. In addition, health services must also be in accordance with the therapy algorithm. The selection of the right oral hypoglycemic (OH) drug greatly determines the success of DM therapy. This study aimed to know the description of conformity of OH drug use based on the national formulary and type 2 diabetes mellitus therapy algorithm at primary health facility X in Surakarta. This research was a descriptive research with data collection in Retrospective from medical record patient. Sample in this research was OH drug in Primary Health Facilities X at Surakarta period January to May 2019. The results showed that patients who received OH drug according to Fornas recommendations were 105. Patients who received OH drug according to the recommendations of the DM Therapy Algorithm were 75. The conclusion of this study is 100% OH drug according to National recommendations and 71,43% OH drug according to DM Therapy Algorithm recommendations Keywords: Conformity, Diabetes, National Formulary, Therapy Algorithm
Evaluasi Perencanaan dan Pengadaan Obat Di RSUD Pandan Arang Boyolali
Authors: Candra Dewi I Gusti Agung Ayu Adi , Dyahariesti Niken , Yuswantina Richa
Published: October 2021

Pengelolaan obat di rumah sakit merupakan salah satu manajemen rumah sakit yang penting terutama pada tahap perencanaan dan pengadaan. Ketidakefektifan dan ketidakefisienannya dapat berdampak negatif terhadap rumah sakit baik secara medis maupun ekonomis. Penelitian ini bertujuan untuk mengetahui keefektifan  dan efisiensi pengelolaan obat pada tahap perencanaan dan pengadaan di Instalasi Farmasi RSUD Pandan Arang Boyolali tahun 2018. Metode yang digunakan dalam penelitian ini merupakan metode deskriptif dimana pengambilan data dilakukan secara retrospektif. Data yang diperoleh berupa data primer dan data sekunder. Hasil penelitian diketahui, pada tahap perencanaan berdasarkan indikator persentase dana 101,6%, penyimpangan perencanaan 140%, pada tahap pengadaan berdasarkan indikator persentase alokasi dana pengadaan obat 33,35%, frekuensi pengadaan tiap item obat tergolong dalam frekuensi rendah (<12x/tahun) sebanyak 124 dan frekuensi sedang (12-24x/tahun) sebanyak 11 item obat, frekuensi kesalahan faktur 0%, frekuensi tertundanya pembayaran 0%. Pengelolaan obat pada tahap perencanaan sudah efisien pada indikator persentase dana dan kurang efektif pada indikator penyimpangan perencanaan, sedangkan pengelolaan obat pada tahap pengadaan yang kurang efektif pada indikator pengadaan tiap item obat, sudah efisien pada indikator alokasi dana pengadaan obat dan sudah efektif pada indikator frekuensi kesalahan faktur serta frekuensi tertundanya pembayaran.Kata kunci: Perencanaan, Pengadaan, Instalasi Farmasi Rumah Sakit.