bluuebunny/crossref_metadata_2025 huggingface dataset:
Labio-palatine Cleft, Morphological Substrate
Authors: Romanec Cristian , Pacurar Mariana , Decusara Mioara , Scutariu Monica Mihaela , Hinganu Delia , Hinganu Marius Valeriu , Ciupilan Corina
Published: February 2020

Labio-palatin clefts are the most common type of craniofacial malformation encountered in practice and among the most common congenital abnormalities; it represent morphological and functional defects in newborns caused by genetically changes or environmental factors; those of the cervico-facial region have an increased incidence due to local embryological complexity and multifactorial etiology. The anomaly, with its variants, results from an inherent defect between the internal and external nasal buds, both from the frontal and upper maxillary bud. Labio-palatine clefts are characterized by a tissue deficiency as well as an abnormal disposition of the present tissues. It is believed that the labial clefts are consecutive to the lack of apoptosis of the ectoderm which envelops the internal maxillary and nasal buds, thus constituting a barrier to the fusion process of buds. Depending on the location and the extentension of the cleft, the labial cleft occurs, or the more frequent, the labial-alveolar cleft. The study group consisted of 22 patients with labio-palatine clefts, of which 16 boys (72.72%) and 6 girls (27.27%), who presented in the clinic for treatment. When the causative factor acts earlier, the clfet develops posteriorly, since mesodermization begins from the posterior to the anterior. The more disturbing factor acts, the greater the cleft. The increase in the incidence of labial-palatine cleft is believed to be mainly due to the increase in the number of women of older gestational age in women; women over 35 years of age have a double risk of having children with labio-palatine clefts, the risk being three times higher for mothers over the 39 years.
Incidence of Resistance Phenotypes of Escherichia coli Strains Isolated from an Obstetrics and Gynecology Unit Unicentric Prospective Transversal Study
Authors: Boruga Ovidiu , Stanca Horia Tudor , Bagiu Iulia Cristina , Horhat Ioana Delia , Craciunescu Mihaela , Cosnita Andrei , Berceanu Vaduva Delia , Chercota Vlad , Milcu Adriana Iuliana , Iovan Ciprian
Published: February 2020

Multiple microbial resistance is a global alarming phenomenon in modern medicine, which is experiencing a decrease in the therapeutic options and in the rate of discovery of new antimicrobials. The aim of this study was to analyze the incidence of Escherichia coli resistance phenotypes to suitable antimicrobial chemotherapies in strains isolated from urine samples. The study was conducted between 01.04.2016 and 31.03.2017 in the Department of Microbiology of the Municipal Emergency Clinical Hospital of Timisoara - Obstetrics and Gynecology unit. We used 1931 urine samples collected from the patients in this department. Identification of pathogens was performed on the API system, and chemotherapy sensitivity testing was based on the disk diffusion method. Of the 1931 urine samples, 210 were non-sterile (94 samples from the obstetrics department, 116 from the gynaecology department). The identified pathogens were Staphylococcus aureus (7 samples), coagulase-negative staphylococci (7 samples), Streptococcus spp. (37 samples), Escherichia coli (138 samples), Klebsiella spp. (9 samples), Proteus spp. (6 samples), Serratia spp. (6 samples). The identified resistance phenotypes for Escherichia coli strains were: wild-type strains (36) 25.92%, penicillinase-secreting strains (50) 35.84%, penicillinase-hypersecreting strains (26) 18.91% cephalosporinases (11) 7.98%, ESBL-producing strains (15) 11.17%. The prevention and spread of multidrug-resistant bacteria requires knowledge of bacterial resistance mechanisms and the development and application of appropriate in-hospital protocols.
Lolium Perenne - A Phytoremediation Option in Case of Total Petroleum Hydrocarbons Polluted Soils
Authors: Masu Smaranda , Cojocariu Luminita , Grecu Eugenia , Morariu Florica , Bordean Despina Maria , Horablaga Marinel , Nita Lucian , Nita Simona
Published: February 2020

Rehabilitation of polluted soils with petroleum products requires a re-vegetation strategy to obtain a green mass cover that can quickly and efficiently cover the polluted soil. For the gradual recovery of the destroyed soil, it was necessary: 1. adequate soil treatments with fertilizer i.e. sewage sludge and fly ash as amendment, 2. plant species selection, 3. agronomical works in accordance with geographical position and climatic conditions. Fertilizers and fly ash create conditions for plant installation, by nutrients insurance. Our experiment was conducted in pots with 91.73�11.12 [gKg-1 D.M (dry matter)] total petroleum hydrocarbons (TPH) polluted soil, fertilised with sewage sludge and fly ash 60 [tha-1] derived from the burning of fossil fuels in thermal power plants. The selected plant species for bio-remediation is Lolium perenne. The selected plant species Lolium perenne is installed on 50-90% of the land surface giving 8 successive crops of grass in the warm season. The TPH reductions of polluted and treated soil were 38.4-56.3 [%]. The biomass did not bioaccumulate chromium at the detection limit. The amounts of cadmium, lead and zink bioaccumulated in the aerial parts were below acceptable limits. The obtained biomass can be used as animal feed or for bedding in shelters. The soil remediation efficiencies of 91.73 � 11.12 [gKg-1 D.M] were directly proportional to the amount of fly ash used.
Extensive Bone Infarctions - an Unexpected Consequence of Corticosteroid Treatment in Idiopatic Polymiositis
Authors: Musetescu Anca Emanuela , Cioroianu Alesandra , Ciurea Paulina Lucia , Florescu D. N. , Georgescu Claudia Valentina , Florescu L. M. , Bumbea Ana Maria
Published: February 2020

Secondary hemochromatosis is a condition generated by defects in the iron metabolism such as elevated intestinal iron absorption and increased iron stores in tissues and organs. The current case report presents a 35-year-old female admitted for inflammatory pain of the left ankle, second and third right MCP joints and right sternoclavicular joint associated with Celsian clinical signs, subcutaneous edema and loss of articular function. The patient is known with beta thalassemia major, secondary hemochromatosis and chronic hepatitis C as a consequence of repeated blood transfusions. We pleaded for the existence of a HC-A associated with microcrystalline calcium pyrophosphate dehydrate crystal deposition (CPPD) disease associated with secondary osteoarthritic changes.
Romanian Pilot Study of Alpha-1 Antitrypsin Detection-Feasibility and Challenges
Authors: Zaharie Ana Maria , Antoniu Sabina , Chorostowska Wynimko Joanna , Mihaltan Florin Dumitru , Deleanu Oana Claudia , Mahler Beatrice , Davidescu Lavinia , Arghir Oana Cristina , Ulmeanu Ruxandra
Published: February 2020

Alpha-1 antitrypsin deficiency (AATD) is an underdiagnosed genetic disorder that manifests primarily through pulmonary and hepatic impairment. In Romania, a targeted detection program testing for AATD was implemented between October 2012 and October 2016. A cohort study enrolled all patients with indication for AATD screening (lung or liver disease, adults and children, index and non-index cases). Testing methods were mainly represented by isoelectric focusing, genotyping and/or sequencing. 620 patients (21 children) were tested (median age 50.0�16.4 years, 58.1% men), 91.9% of proved normal. A total of 50 patients were identified to be carrying a modified genotype (26 men). Hardy-Weinberg equilibrium was used for assessing the frequency of the genetic abnormalities: 1/1.08 PiMM, 1/32 PiMS, 1/28 PiMZ, 1/48 M-rare allele heterozygote, 1/3906 PiSS, 1/2770 PiZZ, 1/1000 PiSZ and 1/12346 for a Z-rare allele heterozygote. Severe AATD was present with a 1% frequency. Prevalence of abnormal genotypes estimated for each at risk category was greater in neonate hepatitis (100%), bronchitis (20%) and adult liver cirrhosis (33.3%). In conclusion, a targeted AATD detection program with this formula is feasible in Romania and will be continued with the implementation of a national registry.
Clinical and Histopathological Parameters Correlate with Microvessel Density but Not with Vascular Endothelial Growth Factor Expression in Ovarian Cancer
Authors: Pirtea Laurentiu , Grigoras Dorin , Secosan Cristina , Sas Ioan , Ilina Razvan , Jitariu Adriana Andreea , Mederle Ovidiu Alexandru
Published: February 2020

Ovarian cancer malignancies have the worst prognosis among all gynecological malignancies. As angiogenesis represents a key step for tumor progression, vascular endothelial growth factor (VEGF) is one of the most discussed pro-angiogenic factors. VEGF expression was investigated in 62 cases of ovarian carcinomas. Microvessel density (MVD) was evaluated by correlating the results with clinical and histopathological parameters. Because of the controversial results reported in other studies, VEGF was assessed together with MVD. Our results suggest a more complex angiogenic mechanism in ovarian cancer based on the discrepancies between VEGF expression, microvessel density and their correlation with clinical parameters. The conflicting data arising from this study supports the implications of different growth factors, others than VEGF in ovarian cancer. This hypothesis is sustained by the lack of correlation between VEGF and clinical parameters, and by the significant correlation between microvessel density and clinicopathological parameters. Thus, further studies are needed for a complete evaluation of angiogenesis in ovarian cancer.
Effects of Acetylsalicylic Acid in Preterm Preeclampsia Prevention
Authors: Serban Denis , Crisan Ciprian , Serban Costela , Micu Serbu Iulia Bianca , Kundani Nilima , Poroch Vladimir , Sharma Abhinav , Buciu Victor , Horhat Ioana Delia , Sas Ioan , Biris Marius , Ratiu Adrian
Published: February 2020

Acetylsalicylic acid, classified under the non-steroidal anti-inflammatory drugs (NSAIDS) has well known anti-inflammatory, anti-pyretic properties, anti-platelet aggregation effect and analgesic properties. Pre-eclampsia (PE) is a pathology of pregnancy characterized by the onset of hypertension and often accompanied by the lost of significant amount of protein in the urine. In pregnant women with risk of preeclampsia, low doses of aspirin have been shown to have a beneficial effect on the incidence of this disorder. Using a retrospective design, we screened for preeclampsia all pregnancies followed in a time interval of 2 years. We have observed that in preeclampsia high risk patients based on the screening done between 11 to 13 weeks and 6 days, the administration of low doses of acetylsalicylic acid reduced the burden of disease. Identifying the pregnancy having high risk for preeclampsia in the first trimester helps us in decision making for initiating prophylactic treatment with Aspirin.
Study of the Presence of Lead in a Series of Foods of Plant Origin
Authors: Apostu Mihai , Tantaru Gladiola , Vieriu Madalina , Bibire Nela , Panainte Alina Diana
Published: February 2020

The objective of the study was to evaluate the presence of lead in several food products of plant origin. An atomic absorption spectroscopic quantitative method for the analysis of Pb+2 was developed and validated using an Analytik Jena ContrAA 300 apparatus equipped with an air-acetylene flame and a high-resolution continuum source. The analyzed food products were wheat, wheat flour, onions, corn, corn flour, carrots, beans, potatoes and cabbage grown in three geographical areas, on three soil types. The results obtained were in line with the limits laid down in Commission Regulation (EC) No 1881/2006 - Consolidated acts as far as the maximum admissible level of Pb+2 in foods.
The Use of Mercury Compounds in the Synthesis of Some Lepidoptera Insect Sex Pheromones with Monoenic Structure
Authors: Andreica Adriana Maria , Gansca Lucia , Ciotlaus Irina , Oprean Ioan
Published: February 2020

New and practical synthesis of (E)-11-tetradecen-1-yl acetate and (Z)-11-hexadecen-1-yl acetate were developed. The synthesis were based on a C12+C2=C14 and C12+C4=C16 coupling scheme. The routes involve, as the key step, the use of the same mercury derivative of the terminal-alkyne w-functionalised as intermediate.The first coupling reaction was effected by adding 1-tert-butoxy-10-bromodecane to monosodate acetylene, obtained in situ from DMSO and sodium hydride. It was prepared 1-tert-butoxy-dodec-11-yne, which is transformed in di[tert-butoxy-dodec-11-yne]mercury, the common intermediate in the synthesis of the two pheromones. In order to obtain (E)-11-tetradecen-1-yl acetate, the mercury derivative was directly lithiated and then alkylated with 1-bromoethane obtaining 1-tert-butoxy-tetradec-11-yne. After reduction with lithium aluminium hydride of 1-tert-butoxy-tetradec-11-yne and acetylation gave (E)-11-tetradecen-1-yl acetate with 99 % isomeric purity. In order to obtain (Z)-11-hexadecen-1-yl acetate, the mercury derivative was directly lithiated and then alkylated with 1-bromobutane obtaining 1-tert-butoxy-hexadec-11-yne. After acetylation of 1-tert-butoxy-hexadec-11-yne and stereoselective reduction in the presence of NiP-2 catalyst gave (Z)-11-hexadecen-1-yl acetate with 90 % isomeric purity.
Mechanistic Investigations of the Organocatalytic Depolymerization of PET Waste with Isosorbide
Authors: Nica Simona , Ionescu Sorana , Hanganu Anamaria , Duldner Monica , Iancu Stela , Sarbu Andrei , Filip Petru , Bartha Emeric
Published: February 2020

Glycolysis of PET waste with isosorbide, a biomass derived diol, was catalyzed by commercially available 1,5,7-triazabicyclo [4.4.0] dec-5-ene (TBD) at temperature up to 190�C when low molecular weight oligomer containing at least one equivalent of isosorbide was obtained. The structural assignment of the oligomer product was established by NMR spectroscopy showing predominantly end-chain bonded isosorbide with exo/endo ratio of 55/45. Mechanistic considerations of the transesterification reaction of isosorbide with dimethylterephthalate (DMT) as model reaction revealed that the hydrogen bonding interaction of TBD with this diol is the favored mechanism pathway. This was established by corroborating solution NMR spectroscopy studies with DFT calculations at B3LYP level where it was observed that isosorbide is hydrogen bonded to TBD through both endo and exo hydroxyl groups. On the other hand, the TBD catalyst reacts with dimethylterephthalate at low temperature forming a stable, easy to handle covalently bonded adduct.
Obtaining Biodiesel with High Oxidation Stability from the Oil Blend Extracted from Seeds of Citrullus lanatus and Vitis vinifera
Authors: Dumitru Mihaela Gabriela
Published: February 2020

The increase of energy demand associated with stringent worldwide emission legislation and the depletion of fossil resources has led to the use of biodiesel and biodiesel blends from various feedstocks. One of the main problems with biodiesel is the susceptibility to oxidation and degradability due to the environmental factors. The oxidation process is complex affecting the fuel quality resulting in choking of injector and formation of deposits in fuel system. Antioxidants are used to limit the oxidative degradation. The present paper review some attempts to use natural and synthetic antioxidants form different papers available in the public domain. Two types of biodiesel from oils of Citrullus lanatus and Vitis vinifera were obtained by base catalyzed transesterification. Peroxide value, iodine value, acid value and induction period were determined monthly to observe the degradation process for biodiesel samples. The biodiesel from Citrullus lanatus 90% and oil of Vitis vinifera 10% exhibits presented the best oxidation stability over a period of 12 months. A single cylinder diesel engine setup was used to determine the performance and gas emissions for biodiesel samples. The results show that biodiesel can be used without engine modification with results comparable with diesel fuel.
Friction and Wear Behaviour of Polyester Nanocomposites with Graphene Oxide and Graphite Investigated Through Block-on-ring Test
Authors: Bastiurea Marian , Dima Dumitru , Hadar Anton , Andrei Gabriel
Published: February 2020

A new class of polyester nanocomposites with graphene oxide and graphite has been obtained through a specific chemical method. Aiming to assess the tribological performance of this type of material, a basic experimental plan has been conceived which includes block-on-ring test, wear rate measurement, Vickers micro hardness test and scanning electron microscopy. Accordingly, the influence of graphene oxide and graphite on coefficient of friction and friction stability were investigated through wear test of nanocomposite blocks against steel rings. At the same time, specific wear rate was inferred in order to examine the mass loss which is strongly dependent on surface micro hardness. After wear test, SEM analysis allowed identification of the transfer film between nanocomposite surface and steel counterpart, and the occurrence of the third body. A careful examination of the friction coefficient recordings has highlighted the effect of the contact condition during the dry sliding test.
The Efficacy of Synthetic Oral Progestin Pills in Patients with Severe Endometriosis
Authors: Bodean Oana , Bratu Ovidiu , Bohiltea Roxana , Munteanu Octavian , Marcu Dragos , Spinu Dan Arsenie , Vacaroiu Ileana Adela , Socea Bogdan , Diaconu Camelia Cristina , Fometescu Gradinaru Delia , Cirstoiu Monica
Published: February 2020

Endometriosis is an important public health issues concerning women of reproductive age due to its debilitating painful symptoms. Deep infiltrating endometriosis is the severe form, involving uterosacral ligaments, rectum, bowel and bladder. There is no optimal treatment for this disease, but there are 3 main therapeutic options: medical, surgical and a combination of both. A modern approach for the treatment of endometriosis pain uses dienogest, a progestin, as a long-term solution for women who do not wish to procreate or to whom surgery is not an option. Dienogest 2mg daily has a positive effect on the reduction of pain and endometrial lesions when used perioperatively or as a long-term postoperative treatment. This article focuses on the literature evidence on the efficacy of newly approved oral synthetic progestins in the treatment of severe endometriosis.
The Effects of Modifying the Catalytically Active Phase Through Ni Impregnation of the Cu-Ru Catalyst on Carbon Support in Nitrobenzene Hydrogenation
Authors: Argesanu Carmen , Matei Dorina , Il Kong Song , Bondarev Andreea , Matei Vasile
Published: February 2020

We report herein on the hydrogenation of nitrobenzene over 5%Cu-1%Ru/C and 5%Cu-1%Ru-8%Ni/C catalysts respectively, using a pilot laboratory installation and their performances in order to outline the effect of Ni addition in the Cu and Ru-based catalyst. The experiments were performed on beds of catalyst extrudate, with a volume of 40 cm3, for a range of temperatures from 45 to 75�C, pressures from 1 to 4 MPa, space velocities from 0.2-0.6h-1, feed ratio H2/C6H5NO2=10/1mol/mol. The performances were evaluated based on conversion values of nitrobenzene and the yields of the most significant reaction products, both of which were assessed through analyses of raw materials and reaction products by GC-MS. Although Ni is widely known as a common catalyst for hydrogenation, we have established the inhibitory effect of Ni addition on the Cu-Ru/C catalyst obtaining, in some cases lower total conversions, but having a potent effect on modifying the selectivity of reaction products, with a quantitatively varying effect depending on working pressure.
Study of the Compatibility of New Biomaterials in Vital Pulp Therapy in Pediatric Dentistry
Authors: Todea Carmen , Igna Andreea , Ogodescu Emilia , Zetu Irina , Ogodescu Alexandru
Published: February 2020

Vital pulp therapy is an expanding concept in pediatric dentistry today thanks to the potential exhibited by new biomaterials to stimulate regeneration of the pulp cells. Biocompatibility, bioactivity and dentin-like physical properties, as well as good handling, fast setting and the possibility to fill large cavities with a single material are some of the ideal properties of materials aimed to heal traumatized and inflamed dental pulps, given by a good balance of their chemical components.
The Investigations of Fe2MnGe Heusler Alloy Using Density Functional Theory
Authors: Gruszka Konrad
Published: February 2020

The paper presents results of computational studies on Fe2MnGe heusler alloy using density functional theory approach. The material exhibit half metalic properties with spin polarization of 98% in the Fermi energy. Paper contain results of three population analysis methods namely L�wdin�s, Henkelman (Bader) and Yu and Trinkle (YT) using Quantum Espresso, Critic2 and Bader Charge Analysis sowtware packages. The charge density visualization planes resulting from Bader analysis are also presented. Studies showed localized-covalent bonding character between transition metals and Ge. The total magnetization is caused mainly by to Mn-d shell electrons, with small Fe and marginal Ge magnetic moments participation.
The Influence of Er:YAG Laser on the Dissolution Rate and Morphology of the Root Cement A scanning electron microscopic study
Authors: Monea Monica , Esian Daniela , Soos Reka , Tohati Adrian , Sitaru Alexandru , Bica Cristina Ioana
Published: February 2020

Lasers can interact with dental tissues inducing changes in tooth characteristics, regarding the surface morphology and elemental composition. The alterations were observed in Calcium, Phosphorus, Sodium, Oxygen and Carbon elements, which influence the resistance and chemical properties of dental hard tissues. The thermal energy used by laser reduces water content of the tissues and as a consequence, the level of oxygen composition decreases after irradiation. Numerous studies had demonstrated its ability to ablate hard-tissues, without any detrimental thermal effects such as cracking or melting for the adjacent tissues. The aim of this article is to present the in vitro effects of Er:YAG laser in comparison with sonic, ultrasonic and manual instruments on the root cement during scaling and root planning, evaluated by scanning electron microscope. The study was conducted on extracted teeth, divided in four groups according to the method used for scaling and root planning. The specimens were analyzed by scanning electron microscopy and the morphological alterations of the cement were evaluated based on a scoring system. Data were statistically analyzed using Mann-Whitney test and the level of significance was set at p[0.05.We noted unfavorable results on the root cement after using Er:YAG laser as craters and cracks induced by heat. There was a greater amount of roughness on the root surface after Er:YAG was used for scaling and root planning compared to manual, sonic and ultrasonic methods. Despite favorable results obtained after the use of Er:YAG laser during periodontal treatment, further clinical studies are necessary in order to determine in which moment of the therapy these methods are most suitable.
Trimetazidine, a Metabolic Modulator, with Cardioprotective Effects Against Myocardial Ischemia
Authors: Ivan Viviana Mihaela , Georgescu Marius , Apostol Adrian , Albulescu Nicolae , Serb Alina Florina , Tatu Carmen Sofica
Published: February 2020

Metabolic therapy constitutes a relatively new therapeutic option for ischemic heart disease (IHD). Metabolic agents including Trimetazidine [1-(2,3,4-trimethoxybenzyl) piperazine] (TMZ) are currently used as anti-ischemic cardiac drugs to alleviate this internal metabolic disturbance. The present study focused on the assessment of the beneficial effects of TMZ as additional medication to the conventional medical therapy in patients with myocardial infarction. The obtained results showed an increase of superoxide dismutase (SOD) activities and a faster normalization of total sialic acid (TSA) levels in patients with TMZ add-on therapy, in comparison to the control group, indicating a stabilization of the ischemic process under TMZ therapy, with decreased free radical production and restoration of the antioxidant capacity and of the membrane lesions. The present findings emphasize the importance of TMZ administration to prevent reperfusion-mediated cardiac injury and dysfunction and demonstrate that this promising therapeutic approach is worthy of further research.
Alkaline-Enzymatic Hydrolysis of Wool Waste for Different Applications
Authors: Berechet Mariana Daniela , Niculescu Mihaela Doina , Gaidau Carmen , Ignat Madalina , Epure Doru Gabriel
Published: February 2020

Wool waste represents a valuable and renewable material with low level of valorization and high potential to be integrated in bioeconomy. The extraction of keratin from wool by-products generated by sheep breeders and furskin industry represents a valuable approach for reducing the environmental pollution with organic and heavy biodegradable waste and a possibility to use a renewable product in agriculture or different industries. Keratin hydrolysates were obtained by alkaline and alkaline-enzymatic hydrolysis with extraction yields of 16.4-43.5%. The obtained keratin hydrolysates were characterized by physical-chemical analysis (dry substance, nitrogen content, pH, ash etc), FT-IR spectra, Dynamic Light Scattering (DLS), electrophoresis (SDS-PAGE) and surface tension (VCA Optima XE). Alkaline and alkaline-enzymatic hydrolyses of wool waste showed the possibility to obtain different keratin polypeptides with suitable properties for application in leather industry or in agriculture.
Synthesis, Characterization and in vitro Biological Evaluation of a New Schiff Base Derived from Drug and its Complexes with Transition Metal Ions
Authors: Mumtaz Amina , Mahmud Tariq , Elsegood M. R. J. , Weaver G. W.
Published: February 2020

New series of copper (II), cobalt (II), zinc (II), nickel (II), manganese (II), iron (II) complexes of a novel Schiff base were prepared by the condensation of sulphadizine and pyridoxal hydrochloride. The ligand and metal complexes were characterized by utilizing different instrumental procedures like microanalysis, thermogravimetric examination and spectroscopy. The integrated ligand and transition metal complexes were screened against various bacteria and fungus. The studies demonstrated the enhanced activity of metal complexes against reported microbes when compared with free ligand.
Ibandronat in the Therapy of Osteoporosis in Turner Syndrome
Authors: Albulescu Dana Maria , Preda Adelina Smaranda , Camen Adrian , Ionovici Nina
Published: February 2020

Turner syndrome represents a condition that associates diverse pathology with somatic, metabolic (diabetes), cardio-vascular, digestive, respiratory and bone involvement along with chromosomal abnormalities. In our study we have analyzed the bone pathology that occurs in Turner syndrome and the response in the therapy with ibandronat. The decrease in value of the bone turn-over biomarkers and the decrease of the T score after the administration of ibandronate p.o. in a monthly dosage demonstrates the efficiency of this bisphosphonate in the treatment of the osteoporosis secondary to sexual hormone deficiency in Turner syndrome.
Applications of Bentonite to Soil Decontamination
Authors: Rusanescu Marin , Rusanescu Carmen Otilia , Voicu Gheorghe , Begea Mihaela
Published: February 2020

A calcium bentonite from Orasu Nou deposit (Satu Mare Romania) was used as raw material. We have conducted laboratory experiments to determine the influence of bentonite on the degree of heavy metal retention. It has been observed that the rate of retention increases as the heavy metal concentration decreases. Experimental studies have been carried out on metal retention ( Zn) in bentonite. In this paper, we realized laboratory experiments for determining the influence of metal (Zn) on the growth and development of two types of plants (Pelargonium domesticum and Kalanchoe) and the effect of bentonite on the absorption of pollutants. These flowers were planted in unpolluted soil, in heavy metal polluted soil and in heavy metal polluted soil to which bentonite was added to observe the positive effect of bentonite. It has been noticed that the flowers planted in unpolluted soil and polluted with heavy metals to which bentonite has been added, the flowers have flourished, the leaves are still green and the plants whose soils have been polluted with heavy metals began to dry after 6 days, three weeks have yellowish leaves and flowers have dried. Experiments have demonstrated the essential role of bentonite for the removal of heavy metals polluted soil.
Assessing Rheological Properties of Cement Paste as a First Step in Predicting Robustness of Self-compacting Concrete
Authors: Dumitrescu Marius , Badanoiu Alina , Voinitchi Constantin Dorinel , Voicu Georgeta
Published: February 2020

This paper proposes a methodology to assess the rheological behavior of cement paste as a first step to linking this behavior to the robustness of the Self Compacting Mortar (SCM) and further extending this to Self-Compacting Concrete (SCC). Cement paste�s rheological behavior was assessed in terms of spread (using a mini-cone) and time of flow (using the Marsh cone). The results show that the type of superplasticizer (SP) admixture has a great influence on the rheological behavior of cement paste and for each combination of binder and superplasticizer admixture there is a specific range of water to binder ratio in which the rheology of paste seems to be appropriate for obtaining a robust SCC mix. The influence of SP and limestone filler addition on the kinetic of cement hydration process was assessed by X Ray Diffraction and thermal analysis (TG-DTA). Based on these results, i.e. an important delaying effect exerted by superplasticizer additions on cement hydration process at early ages (1 day), it can be concluded that when designing SCC for the precast industry - where the early strength of concrete is of high importance, analyzing the early strength of binder paste together with the robustness properties is very important. The correlation between the two aspects - rheology and early strength -is very important in this case in order to obtain applicable results in practice.
The Role of Chemical Factors in Oro-Maxi-Facial Surgery. The effiency of surgical act in lower lip cancer
Authors: Budacu Cristian Constantin , Mihai Constantin , Caraiane Aureliana , Ciurcanu Oana Elena , Balan Mihail
Published: February 2020

Oro-facial soft parts may be the site of benign or malignant tumors, which, although presenting histological similarities, aspects and clinical development vary depending on the affected region. An upper lip lesion that does not heal in a few days could be a big health problem. Also, the presence of chronic inflammation, thickening, or whitish appearance in the lip are all alarm signals. Lip cancer is manifested by the presence of the upper or lower lip tumor, which may be solitary or multiple, ulcers that do not heal for more than three weeks, haemorrhages in the tumor. Sometimes it is considered as being a trenant/delayed herpes, the spinocellular carcinoma of the lip is the most common form of localized cancer in the head and neck level. The lip cancer occurs predominantly in men between 50 and 70 years of age but cases have been identified in young patients aged 20-30 years, too. The study includes 95 patients with lower lip cancer studied in 2016-2017. A good collaboration between ablative surgeon and restorer surgeon gives the patient the best opportunity for complete resection and restoration of the shape and function of the involved structures; the ablative surgeon can remove the tumor without compromising the excision due to a specific reconstruction plan. Reconstruction possibilities from the lower lip were adapted to each patient, depending on the size of the tumor and the properties of the facial tissues.
The Determination of Noxes Emissions in Case of Manual Arc Welding Process with Coated Electrode
Authors: Babis Claudiu , Semenescu Augustin , Chivu Oana Roxana , Gligor Maria Alina , Iacobescu Gabriel , Ghimisi Stefan , Negoita Olivia
Published: February 2020

The occupational risk assessment of a machine building company must cover each activity and workstation, taking into account each component of the production system (work system), each workload, work equipment and the work environment. This assessment is an extremely complicated and complex issue since the production system of such an enterprise is particularly complex and complicated. Welding assembly is a highly polluting technology process, especially of the atmosphere and soil. The formation of gases in the welding process is the result of burning of the electrodes, powders, forming the molten metal bath and making the weld seam. Welding operators are exposed to smoke and toxic gases resulting from the welding process, which can in many cases be hazardous to health. Many acute intoxications that may be caused by excessive exposure to or short exposure to smoke and gas resulting from the welding process have been studied over time. In the paper are presented the elements of risk related to the welding process and the most widespread occupational diseases that can occur in the ranges of the welding operators. The following are presented the noxious emissions from welding and are determined by a practical method the emission of noxious at welding deposition of a welding sample, using the manual arc welding process with coated electrode.
Incidence of Osteoporosis and the Risk of Fracture in Patients with Rheumatoid Arthritis Undergoing Corticosteroid Treatment
Authors: Ene Cristina Gabriela , Rosu Anca , Gheorman Victor , Calborean Veronica , Tenea Cojan Tiberiu Stefanita , Rogoveanu Otilia Constantina , Vladu Mihaela Ionela , Radu Lucretiu
Published: February 2020

Rheumatoid arthritis (RA) is the most widespread inflammatory rheumatic disease with about 10% of all rheumatic diseases and a global prevalence of about 1%. Through its features - joint proliferation, articular panic, articular cartilage degradation and bone erosion � RA has a destructive and disabling character and a major socio-economic impact. Osteoporosis is a bone system disease characterized by loss of bone mass and alteration of bone architecture, with consequences on bone fragility correlated with an increased fracture risk. With a major socio-economic impact, the World Health Organization (WHO) has declared osteoporosis as a public health problem, third on cardiovascular and oncological.
Determination of Antioxidant Components and Activity of Tamarix ramosissima Comparative with Vaccinium myrtillus on Streptozotocin-diabetic Mice
Authors: Rotaru Luciana Teodora , Varut Renata Maria , Banicioiu Covei Mihai , Costache Irina Iuliana , Novac Marius , Nicolaescu Oana , Florescu Cristina , Petrica Alina , Kostici Roxana , Ciobanu Daniela
Published: February 2020

Tamarix ramosissima (Tamaricaceae) is a small tree that grows spontaneously in Europe and Asia, being considered an invasive species in geographical areas with warm climates. The chemical composition is partially elucidated, being empirically used for antiinflammatory, analgesic, antibacterial and antioxidant effect. Our study aimed to evaluate the total polyphenol and flavonoid content of vegetal extracts and to test in vivo antioxidant therapeutic effect of it, comparative with Vaccinium myrtillus, using streptozotocin-induced diabetic mice. After five weeks the animals were sacrificed and we determined erythrocyte activities of superoxide dismutase, glutathione peroxidase, glutathione reductase and level of lipid peroxides as thiobarbituric acid reactive substances. Antioxidant enzymes had highest activities in mice treated with T. ramosissima extract and the level of lipid peroxides was the lowest. The tested extract had higher content of polyphenols comparative with V. myrtillus. Our results sustain the efficiency of T. ramosissima extracts on normalizing the effects of oxidative stress in diabetes.
In vitro Assessment of the Effect of Opalustre Bleaching System on Dental Enamel
Authors: Pancu Galina , Stoleriu Simona , Tofan Nicoleta , Nica Irina , Ghiorghe Cristina Angela , Iovan Gianina , Moldovanu Antonia , Macovei Georgiana , Andrian Sorin
Published: February 2020

The study was performed to investigate the changes induced by mechanical-chemical action of a bleaching product on dental enamel and to assess the effect of some remineralization products containing calcium, phosphate, and fluoride applied in conjunction with the bleaching product by surface roughness analysis using profilometry. Forty tooth samples were randomly divided in three study groups and a control group. In control group (group IV) the samples were maintained in artificial saliva. The study groups were as follows: group I-samples submitted to bleaching procedure using Opalustre (3 times a day, 1minute each), group II-samples submitted to remineralization and then to whitening, group III-samples submitted to remineralization, whitening and then remineralization. The surface roughness was determined in relation to a reference surface using Portable Surface Roughness Measuring Tester SJ-210 (Mitutoyo, America Corporation, USA). The bleaching system Opalustre increased the roughness of enamel and the product that contains calcium, phosphate and fluoride applied before and after bleaching improved the roughness parameters.
An Unusual Case of Accidental Carbon Monoxide and Ethanol Intoxication in Two Commorientes Deaths
Authors: Dumbrava Dan Perju , Radu Carmen Corina , Iov Tatiana , Damian Simona Irina , Sandu Ion , Timofte Daniel , Chiroban Ovidiu
Published: February 2020

Death by intoxication represents an important cause of violent deaths which could be easily prevented. Accidental ethanol and carbon monoxide intoxications produce the most frequent causes of violent deaths among civilians in Romania. To provide an insight in these types of deaths and to bring attention upon the clinical and biological manifestations as well as of the typical morphologically findings, the authors present a strange case of fatal intoxication due to carbon monoxide in an 88 years old male, found in his bed. Moreover, because of the simultaneous death of the male�s wife in the attic of the house, with ethanol intoxication, we would also like to bring attention to the juridical notion of commorientes, since in the establishing of its constituting characteristics the forensic expertise plays a decisive role.
Radioactivity - Risk Factor in Oral Health and of Structural Dental Anomalies
Authors: Tigmeanu Codruta Victoria , Popovici Ramona Amina , Porumb Anca , Podariu Angela Codruta , Ardelean Lavinia , Olariu Iustin , Corlan Ion Virgil , Adomnicai Mihaela Florica , Roi Alexandra
Published: February 2020

The dentition goes through a complex process of development, a process that can be influenced by internal and external factors. Our study was perfomed on a group of 1673 children from different areas in Bihor county. The uranium mining exploitation in this specific area is very popular, but with an unfortunate consequence: pollution. This factor has had a great impact upon the workers, but also the surrounding areas. The aim of the present epidemiological study is to evaluate the incidence of dental anomalies upon the targeted group and to identify the correlation between the impact of the pollution upon the development of the dentition. All the data was obtained during a clinical examination, documented and afterwards statistically analyzed. Our study concluded that the examined subjects presented with a high percentage of structural dental anomalies, with an average incidence in the polluted areas that can be explained by the interactions that occur and the influence of the radioactive substances upon the development.
Orthodontic Mini-Implants Hybrid Expanders in Palatal Expansion
Authors: Szuhanek Camelia , Nagib Riham , Sinescu Cosmin , Negrutiu Meda Lavinia , Manea Nicoleta , Buzatu Roxana , Dumitrescu Stefania , Mesaros Anca , Cocir Razvan , Schiller Leonora , Sarbu Adina
Published: February 2020

The purpose of this case report is to evaluate the role of mini-implants hybrid expanders in the orthodontic treatment of narrow maxilla. A female patient with a skeletal asymmetry and unilateral posterior crossbitepresented for orthodontic treatment. Digital records were sent to the orthodontic laboratory. The orthodontic lab made the mini-implants hybrid expanders and a 3D surgical guide for an accurate insertion of the mini-implants. After two months, a successful expansion of the maxilla was obtained. Orthodontic mini-implants hybrid expanders could eliminate surgical treatemnt in many narrow maxilla cases.
Chemical Composition and Active Properties Evaluation of Wild Oregano (Origanum Vulgare) and Ginger (Zingiber Officinale-Roscoe) Essential Oils
Authors: Deleanu Mariana , Popa Elisabeta E. , Popa Mona E.
Published: February 2020

The compounds in Ginger (Zingiber officinale-Roscoe) essential oil provenience China and wild oregano (Origanum vulgare) essential oil of Romanian origin were identified by GC/MS and their antioxidant and antifungal properties were evaluated. Wild oregano oil was characterized by high content of oxygenated monoterpenes hydrocarbons (84.05%) of which carvacrol was the most abundant (73.85%) followed by b-linalool (3.46%) and thymol (2.29%). Ginger oil had a higher content of sesquiterpene hydrocarbons including zingiberene (31.47%), b-sesquiphellandrene (13.76%), a-curcumene (10.41%), a-farnesene (8.31%) and b-bisabolene (7.55%) but a lower content of oxygenated monoterpenes (7.97%). The high content of oxygenated monoterpens of wild oregano oil is in accordance with total content of polyphenols determined by the Folin�Ciocalteu method (6.71�0.73 mg of gallic acid equivalent per g oil). Ginger oil had only 1.34�0.22 mg gallic acid equivalent per g oil. Wild oregano oils exhibited appreciable in vitro antioxidant activity as assessed by 2, 2`-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and 2,2�-azino-bis (3 ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS). The sample concentration required to scavenge 50% of the DPPH free radicals was 0.76�0.13 mg/mL for wild oregano oil compared to 20.22�2.12 mg/mL for ginger oil. Also, wild oregano oils showed significant inhibitory activity against selected pathogenic fungi (Fusarium oxysporum, Aspergillus flavus and Penicillium expansum). 1�L of oregano oil is sufficient for almost 75% growth inhibition of Aspergillus flavus compared to ginger oil which shows antifungal activity at 240�L for 78% growth inhibition. It can be concluded that wild oregano oil could be used as food preservative in some food products in which Fusarium oxysporum, Aspergillus flavus and Penicillium expansum could grow and have potential to produce health hazards mycotoxines.
Assessement of Water Quality Parameters in Some Potential Pollutant Areas from Romania
Authors: Gheorghe Catalina Gabriela , Bondarev Andreea , Onutu Ion
Published: February 2020

Monitoring of environmental factors allows the achievement of some important objectives regarding water quality, forecasting, warning and intervention. The aim of this paper is to investigate water quality parameters in some potential pollutant sources from northern, southern and east-southern areas of Romania. Surface water quality data for some selected chemical parameters were collected and analyzed at different points from March to May 2017.
Laser Use in Endodontic for Increase the Adhesion of Root Canal Filling. A synchrotron radiation micro tomography study
Authors: Todea Carmen , Mocuta Daliana , Manescu Adrian , Semez Gianfranco , Giuliani Alessandra , Luca Ruxandra , Ogodescu Alexandru
Published: February 2020

The aim of the present paper is to explore, through a high-resolution synchrotron radiation-based micro computed tomography experiment, the efficiency of the Er:YAG laser involvement in the debridement of the root canal of pathologic teeth, applied after the chemo-mechanical treatment of the canal. The adhesion quality of root canal filling is the consequence of the root canal cleaning and shaping, thus preventing the leakage. Twelve extracted single-rooted teeth were considered. The first 5 mm of the roots, corresponding to the apical region of the teeth, were initially investigated through high-resolution synchrotron radiation phase-contrast micro computed tomography. Afterwards, a chemo-mechanical endodontic treatment was performed and the same region of the teeth was imaged again. Finally, an Er:YAG laser with PIPS tip treatment was applied on the same teeth and a last tomographic scan was done. The chemo-mechanical treatment properly removed the necrotic tissue only in the upper part of the apical area of root canal, but tissue debris were found in the lower and partially also in the medium and upper part of the apical region, especially when the apical area exhibited a larger curvature. The laser treatment applied afterwards gave good results in terms of removing the debris from the apical area of root canal, mainly when they remained in the main canal. The present study proves the capability of Er:YAG with PIPS tips laser treatment to enhance the removing of tissue debris from the apical region of root canals after a chemo-mechanical treatment. The high-resolution synchrotron radiation-based phase contrast micro computed tomography is the most powerful tool for a non-destructive 3D investigation method of the root canal morphology analysis and a proper characterization technique for the assessment of the endodontic treatment.
The Dinitrophenol and Potassium Iodate Influence on Hordeum Vulgare Seedlings Viability\
Authors: Todirascu Ciornea Elena , Dumitru Gabriela , Sandu Ion
Published: February 2020

The using of the pesticides of dinitrophenol type in agriculture has as consequence the major pollution of the environment, the plants taking these substances from the soil and once with these ones they reach in the human and animal organism where they product disequilibrium that are interpreted through the accumulation of free oxygen radicals with direct repercussions on the antioxidant enzyme�s synthesis intensification and on their activity�s increase. The apply of treatments on the barley seeds had significant effects regarding the seeds� germination, the young plants� growth, the oxidative stress enzymes� activity, but also regarding the content of photoassimilators and carotenoids pigments.
Dental Inclusion of Canine and Wisdom Tooth in Orthodontics Chemical Necroses
Authors: Budacu Cristian Constantin , Ioanid Nicoleta , Romanec Cristian , Balan Mihail , Pavel Liliana Lacramioara , Pacurar Mariana , Rosu Sorana
Published: February 2020

Canine plays an important role in the dento-maxillary system. From a functional point of view, it provides the canine guidance, by positioning it in the frontal area, has a role in facial aesthetics. It plays an important prosthetic role by having the longest root and one of the longest arcade teeth. Three molars represent the last teeth that erupt in the arches both in the jaw and in the mandible, which is why they remain the most frequently included.Canine incidence is quite common following the wisdom tooth. It can be unilateral or bilateral and is more common in the upper jaw. The canine may remain included at the vestibular, palatal or between the two bones. A separate entity is the incision of the canine in the edentulous mandible or jaw. The study included 213 cases with dento-alveolar pathology, of which 128 patients were selected with dental inclusion. Our study reports that the first three molars are frequent, followed by the canine as opposed to other studies conducted by Guzduz K in 2011 and Fardi A of the same year bringing the canines first (Fardi, Guzduz). Some studies attribute the first place to the superior canine in terms of frequency, but they are abstracted from the molar three inclusion that they consider as most frequently (Compoy). The most common tooth in inclusion is the third molar (lower and upper) followed by the upper canine; the most commonly affected are women for both canine and molar.