bluuebunny/crossref_metadata_2025 huggingface dataset:
Tulio Vásquez Betancourt: pensamiento y vigencia. Una crónica para recuperar la memoria desde la historia del municipio de Cisneros
Authors: Villegas Bohórquez Farid
Published: June 2020

Esta crónica es una aproximación a la figura pública de un hombre notable en el contexto del pensamiento moderno del departamento de Antioquia: el doctor Tulio Vásquez Betancourt, médico egresado de la Universidad de Antioquia en 1929. La perspectiva narrativa se centra en elementos de familia –paradigmas y valores– que llevan a su definición ciudadana, al encuentro de su carácter y sus realizaciones; evocando lo que fue su desempeño y gestión en la municipalidad de Cisneros. El doctor Tulio Vásquez Betancourt, definió en Cisneros dos proyectos vitales: su realización como médico y la vocación política. Aunque la brevedad de su vida solo alcanza los 36 años de edad, largo es el historial de sus actuaciones. Entonces, desde una mirada de contexto que atraviesa social y culturalmente al municipio, por los afectos y raigambres que él, como personaje sembró en esta localidad, y haciendo una retrospectiva de su vida, se da paso a esta remembranza. La pretensión académica es hacer un aporte historiográfico desde la Corporación Universitaria Remington, a la reivindicación de los personajes que han aportado a la evolución histórica de la cultura en Antioquia.
El sentido ético y las facultades de derecho
Authors: Chaves-López José Luis
Published: June 2020

Las facultades de derecho deberían ser, por excelencia, el lugar donde el sentido ético, que enmarca derechamente la vida de nuestros estudiantes y futuros abogados, se origina, se desarrolla y se forma. Sin embargo, la realidad es diferente al sueño y anhelo de quienes se inician en esta profesión y con preocupación miran como se trasgreden los principios que se enseñan en la academia, con tal de lograr los objetivos y, en consecuencia, son muy diferentes la teoría y la práctica. La filosofía que sostiene el sentido ético pierde su sabor y se olvida el significado y el valor de lo esencial. El derecho, en su práctica, colisiona con los principios personales e incluso constitucionales.
Educación a distancia y virtual: enfoque conceptual y metodológico en la Corporación Universitaria Remington
Authors: Gallego Vásquez Jorge Enrique
Published: June 2020

La educación a distancia tradicional y virtual en Colombia ha tenido un desarrollo significativo en los últimos 10 años, gracias a las tendencias mundiales en el uso de las TIC y las políticas del gobierno nacional orientadas a la ampliación de cobertura, la incorporación de TIC en la educación y el fortalecimiento a los programas técnicos y tecnológicos en la educación superior. Este artículo presenta un análisis del desarrollo de las modalidades de educación a distancia en Colombia y una reflexión sobre el enfoque conceptual y metodológico que la Remington en sus 12 años de experiencia en educación a distancia ha desarrollado para garantizar por un lado la cobertura que hoy tiene en todo el país y por otro lado la calidad del proceso de formación en la aplicación del modelo de educación a distancia y virtual institucional en todos y cada uno de sus Centros de Atención Tutorial (CAT), desde un enfoque académico.
Starch Digestion-Related Amylase Genetic Variants, Diet, and Changes in Adiposity: Analyses in Prospective Cohort Studies and a Randomized Dietary Intervention
Authors: Admin Ada , Heianza Yoriko , Zhou Tao , Chen Yuhang , Huang Tao , Willett Walter C , Hu Frank B. , Bray George A. , Sacks Frank M , Qi Lu
Published: June 2020

Salivary amylase, encoded by the AMY1 gene, is responsible for the digestion of carbohydrates.
We investigated associations of the AMY1
genetic variations with general and central adiposity changes considering
dietary carbohydrate intake among 32054 adults from 4 prospective cohort
studies. A genetic risk score (GRS) was calculated based on nine AMY1 single-nucleotide polymorphisms,
with higher AMY1-GRS indicating higher activity of salivary amylase. We
meta-analyzed interactions between AMY1-GRS and dietary intake for changes in general
and central adiposity over 5.5–10 years. We found that carbohydrate food intake
significantly altered associations of AMY1-GRS with changes in body mass
index (Pinteraction=0.001)
and waist circumference (Pinteraction
<0.001). Results were consistent and significant in female cohorts rather
than in male cohorts. Among women, higher AMY1-GRS was associated with more
increases in adiposity if dietary carbohydrate food intake was high, while higher
AMY1-GRS was associated with less gains in adiposity when the dietary intake
was low. Also, in a 2-year randomized dietary intervention trial, associations
of AMY1-GRS with changes in weight (Pinteraction=0.023) and waist
circumference (Pinteraction=0.037)
were significantly modified by carbohydrate intake. Our results suggest the
importance of precision nutrition strategies considering participants’ genetic
adaptation to carbohydrate-rich diets in regulating general and central adiposity.
ProLab: психофизически равномерная проективная система цветовых координат
Authors: Коноваленко Иван , Смагина Анна , Николаев Дмитрий , Николаев Петр
Published: June 2020

В работе предлагается ввести новое пространство цветовых координат proLab, связанное с CIE XYZ трехмерным проективным преобразованием. В статье показывается, что по психофизической равномерности, оцениваемой с помощью метрики STRESS по отношению к формуле цветовых различий CIEDE2000, предлагаемое пространство значительно опережает широко используемую систему координат CIELAB, хотя и уступает современной CAM16-UCS. Угловые метрики ошибок определения цветности, обычно используемые в линейных цветовых пространствах, могут использоваться и в proLab, поскольку проективное преобразование сохраняет линейность многообразий. При этом, в отличие от линейных пространств, угловые ошибки, различные по цветовому тону, в proLab нормированы в соответствии с порогами цветоразличения человека. В работе также показывается, что гетероскедастичность дробового шума в proLab оказывается меньшей, чем в CAM16-UCS и стандартных цветовых пространствах. Это делает proLab удобной координатной системой для линейного цветового анализа — решения задач линейной регрессии в цветовом пространстве.
A Review on Unstructured Data using k-Mean Algorithm
Authors: Sharma Akhilesh
Published: June 2020

Unstructured data are the data without identifiable structure, audio, video and images are few examples. Clustering one of the best techniques in the knowledge extraction process. It is nothing but a grouping of similar data to form a cluster. The distance between the data in one cluster and the other should not be less. Many algorithms are practiced for clustering, in that k-mean clustering is one of the popular terms for cluster analysis. The main aim of the algorithm is to partition the dataset into k clusters based on some computational value. The limitation of k-mean clustering is that it can be applied to either structured or unstructured, not in combination with both. This paper overcomes that limitation by proposing a new k –mean algorithm for extracting hidden knowledge by forming clusters from the combination of unstructured datasets.
REVITALISASI RUANG TERBUKA HIJAU DI WILAYAH URBAN: ELABORASI HASIL FOCUS GROUP DISCUSSION (FGD) PERENCANAAN TAMAN MAJU BERSAMA DI KELURAHAN GANDARIA UTARA DI JAKARTA SELATAN
Authors: Hasibuan Mohammad Sanjiva Refi , Sidabutar Lasmaria
Published: June 2020

Taman Maju Bersama (TMB) adalah salah satu program pemerintah Provinsi DKI Jakarta dalam menyediakan ruang terbuka hijau di kawasan perkotaan. Dalam proses perencanaannya, program TMB melibatkan partisipasi aktif masyarakat dengan mengadakan kegiatan Focus Group Discussion (FGD) untuk mendapatkan masukan-masukan (input) yang positif demi kelancaran program TMB. Kegiatan FGD ini melibatkan instansi pemerintah tingkat kelurahan dan kecamatan, RT, RW, tokoh masyarakat, perwakilan warga lokal, kelompok PKK, Karang Taruna, hingga komunitas yang terdapat pada daerah tersebut. FGD dilaksanakan dalam tiga tahap yaitu pada tahap awal perencanaan, tahap penyampaian konsep dan desain, serta tahap akhir sosialisasi desain akhir kepada masyarakat. Teknik pelaksanaan FGD yang digunakan adalah diskusi atau tanya jawab secara langsung dan tertulis. Teknik tertulis lebih efektif digunakan dalam mendapatkan ide, masukan, dan komentar dari masyarakat. Hasil dari kegiatan FGD akan menjadi dasar pertimbangan dan masukan bagi konsultan perencana dalam merencanakan dan merancang sebuah taman yang fungsional dan estetis.Kata Kunci: Taman Maju Bersama; Focus Group Discussion; Partisipasi; Perencanaan; Taman.AbstractTaman Maju Bersama (TMB) is one of the DKI Jakarta Provincial Government programs in providing green open space in urban areas. In the planning process, the TMB program involves the active participation of the community by holding Focus Group Discussion (FGD) activities to obtain positive inputs for the smooth running of the TMB program. This FGD activity involved government agencies at the village and sub-district level, RT, RW, community leaders, representatives of local residents, PKK groups, Youth Organizations, and communities in the area. The FGD was carried out in three stages, namely in the initial stages of planning, the stage of conceptual delivery and design, and the final stage of the final design socialization to the community. The FGD implementation technique used was direct and written discussion or question and answer. Written techniques are felt to be more effective in getting ideas, input, and comments from the public. The results of the FGD activities will be the basis for consideration and input for planning consultants in planning and designing a park that is functional and aesthetic.Key words: Taman Maju Bersama; Focus Group Discussion; Participation; Planning; Park
MANFAAT KEGIATAN SUKARELA TAMAN CERDAS GANESHA DI KABUPATEN BULELENG BAGI MAHASISWA PENGELOLA
Authors: Apsari Ratih Ayu , Sariyasa Sariyasa , Suweken Gede , Sukajaya I Nyoman
Published: June 2020

Taman Cerdas Ganesha (TCG) merupakan kegiatan mengajar sukarela yang dibentuk atas kerja sama perguruan tinggi dan komunitas sosial yang berlokasi di Kabupaten Buleleng-Bali, Indonesia. Kegiatan ini memberikan kelas gratis setiap hari Minggu bagi siswa-siswa Sekolah Dasar (SD) di beberapa desa binaan. Pengajar sukarela merupakan tim yang terdiri dari mahasiswa dengan dimentori oleh dosen. Selain dimaksudkan untuk membantu pemerataan akses pendidikan, kegiatan ini juga bertujuan untuk memupuk sikap mental sebagai pengajar sukarela di kalangan mahasiswa. Setiap semesternya ada sekitar 100 hingga 120 mahasiswa yang terlibat sebagai sukarelawan. Metode yang dilakukan untuk pengabdian ini adalah dengan Participatory Rural Appraisal dimana subjek diajak terlibat langsung untuk memahami keseluruhan pengabdian, mulai dari merancang, melaksanakan hingga mengevaluasi. Untuk mengevaluasi kegiatan, 75 mahasiswa yang pernah mengajar sukarela di TCG diminta mengisi kuesioner terkait dengan kegiatan yang dilakukan. Data yang masuk kemudian dianalisis secara deskriptif kuantitatif untuk melihat bagaimana sikap mental kerelawanan mahasiswa yang terlibat dalam pelaksanaan TCG. Analisis data menunjukkan bahwa mahasiswa yang pernah terlibat sebagai sukarelawan merasakan kegiatan ini berguna dan sangat baik untuk dilanjutkan, tidak mengganggu waktu belajar maupun istirahat dan memotivasi semangat berprestasi.Kata kunci: Kegiatan Sukarela; Sukarelawan; Pengabdian; Taman Cerdas Ganesha.AbstractTaman Cerdas Ganesha (TCG) is a social voluntary teaching program initiated by the cooperation between university and community located in Buleleng-Bali, Indonesia. The program provides a free weekly classroom for elementary school students in several villages and suburbs. The volunteers were the prospective mathematics teachers and mentored by the lecturers. Besides to evenly distribute the educational access, TCG was aimed to promote voluntary attitude of the university students. In every semester, there are 100 to 120 students who participate as voluntary teachers. The method employed in the TCG program was Participatory Rural Appraisal where the subjects were involved to understanding the whole community service started from designing, implementing and evaluating the lesson program. To assess the benefits of the voluntary program to the volunteers, we asked 75 participants to fulfil the questionnaire. The data were analyzed quantitatively using descriptive method to observe how the participants’ voluntary attitudes were developed during the event. The result showed that the university students who participate as volunteers felt the program useful to help the young students in rural area. They also did not think the voluntary program as a burden for them. Hence, it is recommended to continue the program to wider targeted subjects.Keywords: Voluntary Attitudes; Volunteer; Community Service; Taman Cerdas Ganesha.
Analisis Kinerja Aparatur Sipil Negara di Lingkungan Sekretariat Daerah Kabupaten Muara Enim
Authors: Nadjib Abdul
Published: June 2020

At time advances in technology today, the public can directly supervise the performance of employees in government institutions., therefore the demands of working professionally must be realized in daily activities by the state civil apparatus. Considering the importance of the quality of the performance of the state civil apparatus for the progress of the nation and state, this study aims to analyze and describe how the performance of the state civil service, especially in the scope of the Regional Secretariat of Muara Enim Regency based on the specified performance indicators. This research is qualitative in nature, starting with the determination of respondents as sources of information (informants) until a descriptive analysis is carried out on the data obtained and grouped according to each indicator. The number of informants is twentyfive (25) people and the number of indicators is eight (8) items. The results showed that 59.4% of employee performance was acceptable or good, meaning that it was feasible to meet the criteria of quality of work, quantity of work, timeliness, discipline, effectiveness, independence, work in teams and responsibilities. While the remaining 40.6% of employees are rated as not having good performance. Some factors as determinants of employee performance include educational background, experience, ability to adapt, creativity, loyalty, and work ethic. There are still employees who have low competence, lack of willingness to learn, low competitiveness and lack of creativity, making employee productivity low.
La otra prédica: la huelga de la Universidad de París (1229-31) como 'escuela de guerra' del intelectual del sistema
Authors: Rivas Damian Andres
Published: June 2020

A partir del estudio de sermones de miembros de la Iglesia, predicados durante la huelga de la Universidad de París (1229-31), se analizan las formas en que los distintos segmentos eclesiásticos intervinieron contra la corporación que buscaba su autonomía. Construyeron su prédica para interpelar al público escolar que no había abandonado la ciudad. Esto permite abordar, por un lado, los objetivos de la Iglesia para dominar la universidad y sus modelos educativos; por el otro, la reacción que desplegó frente a la corporación como contra los movimientos comunales, en un marco de conflictos que buscaban encuadrar los espacios urbanos en el feudalismo. Se caracteriza el rol de los estudios en el programa político de la Iglesia reformada para la creación de nuevos cuadros que encabezaron aquella regimentación, donde surgió un nuevo actor clave: las órdenes mendicantes. A partir del análisis crítico de la interpretación liberal de las revueltas, representada por José Luis Romero, se reflexiona sobre el lugar que ocupó la lucha de los escolares parisinos en el marco de los conflictos urbanos para pensar el rol de la Iglesia en el proceso de ampliación del poder feudal.
Entre servidumbre y trabajo asalariado: la historiografía castellana sobre las relaciones de arrendamiento en el mundo concejil bajomedieval.
Authors: Colombo Octavio
Published: June 2020

El objetivo del presente trabajo es realizar un análisis crítico de la historiografía de las últimas décadas referida a las relaciones de arrendamiento de la tierra en los concejos castellanos de la baja Edad Media. Tales contratos vinculan a los grandes propietarios de los concejos con los campesinos de las aldeas. Se presenta en primer lugar la tesis sobre el carácter feudal de las oligarquías concejiles, del cual se derivaría el supuesto carácter servil de las formas de explotación del trabajo. Luego se presentan distintos enfoques alternativos sobre los arrendamientos, que abarcan desde su supuesto carácter de contratos libres hasta la interpretación que los asimila a relaciones asalariadas. El objetivo del análisis es mostrar que los arrendamientos son en esencia formas de movilización de la fuerza de trabajo campesina. Por lo tanto, obedecen a una racionalidad específica de control de los productores por parte de los propietarios de la tierra, cuyas modalidades concretas deben estudiarse con más profundidad.
Main Character’s Personality Conflict in Aladdin Movie
Authors: Nolen Nolen , Arianto Tomi
Published: June 2020

Abstrak: Dalam jurnal ini bertujuan untuk menemukan konfilk kepribadian karakter utama yang direpresentasikan melalui id, ego, dan superego dominan yang terdapat dalam karakter Aladdin dalam film Aladdin. Dalam makalah ini digunakan teori psikologi Sigmund Freud yang menyatakan bahwa ada tiga struktur yang dapat membentuk watak seseorang. Tiga struktur tersebut yaitu id, ego, dan superego. Penulis menggunakan metode deskriptif untuk menjelaskan id, ego, dan superego dalam karakter Aladdin. Penulis memperoleh data dari menonton film Aladdin yang dirilis pada tahun 1992, kemudian mencatat dan memberi tanda dimana karakter Aladdin menunjukkan sisi id, ego, dan superegonya. Hasil dari penelitian ini adalah id Aladdin terdapat disaat Aladdin bermimpi ingin menjadikan hidupnya lebih baik dan watak Aladdin yang tegar meskipun dihina oleh orang sekitar. Dalam penelitian ini penulis berharap agar penelitian ini berguna dan membantu untuk siapapun yang membaca, khususnya dalam karya sastra. Kata Kunci: Id, Ego, Superego, Teori Sigmund Freud, Watak. Abstract: In this journal aims to find the main character’s personality conflict reflected from id, ego, and superego dominant that contained in Aladdin's character in film Aladdin. In this paper, the writer will use psychological theory of Sigmund Freud that states that there are three striking features that can shape a person's character. The three structures are id, ego, and superego. The author uses descriptive methods to explain the id, ego, and superego in the Aladdin character. The author obtained data from watching Aladdin which was released in 1992, then recorded and gave a sign where the character of Aladdin showed the id, ego, and superhero side. The results of this study are that Aladdin was present when Aladdin dreamed he wanted to make his life better and his character was strong despite being insulted by people around him. In this study the authors hope that this research is useful and helpful for anyone who reads, especially in literary works. Keywords: Id, Ego, Superego, Sigmund Freud's theory, Character.
Economic analysis of law: incompletude de informações e a Lei 11.101/05
Authors: Lana Henrique Avelino
Published: June 2020

Resumo: Pretende-se neste trabalho, via Análise Econômica do Direito, identificar, de forma construtiva, que a atual redação da Lei 11.101/05 enseja assimetria de informações, o que contribui para a sua ineficiência. A metodologia a ser utilizada é de método dedutivo, mediante abordagem explicativa e descritiva, além de pesquisa bibliográfica. Inicialmente será feita uma contextualização do tema, mediante abordagem dos princípios da função social e preservação da empresa. Após, serão identificados os aspectos existentes na Lei de Recuperação de Empresas e Falência que permitem afirmar que há, sim, forte ensejo à assimetria de informações.
O Jus Postulandi na Justiça do Trabalho: Uma análise acerca da sua eficácia como meio de assegurar a garantia constitucional do acesso à justiça
Authors: Rocha Cláudio Jannotti , Ferreira Vanessa Rocha , Rodrigues Gabriel Neves Bittencourt
Published: June 2020

O Jus Postulandi figura como um dos principais instrumentos processuais no que tange a garantia constitucional do acesso à justiça, vislumbrando exaltação por grande parte dos operadores do Direito, pois seria uma forma de garantir àqueles que não possuem um efetivo poder econômico, o direito de guerrear no judiciário em busca de seus interesses. Em contrapartida, outros juristas entendem que o instrumento seja uma afronta ao dispositivo constitucional que prevê a indispensabilidade do advogado na administração da justiça. Para estes, o instrumento processual em questão acabaria por colocar o trabalhador em pés de desigualdade diante do empregador hipersuficiente, violando assim a isonomia processual. Em face do exposto, o presente artigo se propõe a analisar os pontos positivos e negativos deste instituto, bem como a sua eficácia como meio de assegurar o justo e efetivo acesso ao poder judiciário, para ao final refletir sob a sua manutenção no ordenamento jurídico pátrio.
MicroRNAs de plantas sob estresses típicos da caatinga
Authors: Sá Clebiano da Costa , Diniz Michely Correia
Published: June 2020

Em vegetais, respostas fisiológicas ao estresse estão relacionadas a mecanismos de regulação gênica, que envolve pequenas moléculas de RNA não codificante de proteína, conhecidas como microRNA (miRNA). Em meio ao grande volume de dados acerca dos miRNAs, sejam sequências, relações funcionais ou características, a utilização de ontologias têm se destacado como alternativa na organização e recuperação da informação, possibilitando a criação de novos conhecimentos a partir da análise integrada dos dados existentes. O objetivo deste trabalho foi montar uma rede integrativa de miRNAs de plantas sob estresses típicos da Caatinga, através de análises computacionais, realizando buscas nas principais bases de dados, e compreendendo as relações dos miRNAs com seus alvos e com o tipo de estresse. Foram encontradas nove (09) famílias de miRNAs comuns às três categorias de estressse estudadas: déficit hídrico, elevadas temperaturas e salinidade, sendo eles miR159, miR166, miR168, miR172, miR395, miR482, miR530, miR1446 e miR1447. Esse trabalho contribuiu ao apresentar o panorama de miRNA vegetais, com suas características, identificando e selecionando a ocorrência de miRNAs responsivos a apenas um tipo de estresse, enquanto outros estão relacionados a diferentes estresses; esses dados representam um ponto de partida para pesquisas com miRNA em espécies da Caatinga.
Polylactic acid scaffolds obtained by 3D printing and modified by oxygen plasma
Authors: Barud Hernane Silva , Machado Lorenzo Gouvêa , Zaldivar Mayté Paredes , Iemma Mônica Rosas da Costa , Cruz Sandra Andrea , Rangel Elidiane Cipriano , Nassar Eduardo José
Published: June 2020

The purpose of tissue engineering is to repair, replace, and regenerate tissues and organs. For this aim, materials supports, as polylactic acid (PLA) are used. PLA is a thermoplastic polymer that presents biodegradability, biocompatibility and good processability. PLA scaffolds can accurately constructed by 3D printing. Then, the objectives of this work were to modify the hydrophobic surface of PLA scaffolds using oxygen plasma and to study the cell viability and proliferation. The characterization was done by AFM, contact angle, FTIR and studies of proliferation and cell viability. Results showed that the material acquired hydrophilic properties by the presence of oxygen reactive species and by contact angle decrease. It was also observed an increase in the surface roughness. We can conclude that although the surface modifications were effective and the PLA scaffolds were not cytotoxic, there were no improvements in the proliferation process with the studied osteo-1 lineage cells.
Implementasi Load Balancing dan Failover to Device Mikrotik Router Menggunakan Metode NTH (Studi Kasus: PT.GO-JEK Indonesia)
Authors: Mustofa Achmmad , Ramayanti Desi
Published: June 2020

Perkembangan jaringan komputer dan internet yang begitu pesat pada sekarang khususnya internet sebagai media informasi tentunya harus memiliki kualitas koneksi yang baik. Begitu juga yang terdapat pada PT.Gojek Indonesia yang telah memakai dua ISP (internet service provider). Saat banyak permintaan dari pemakai maka perangkat jaringan akan terbebani karena harus melakukan banyak proses pelayanan terhadap permintaan dari pengguna. Solusinya adalah dengan membagi beban trafik yang datang ke perangkat jaringan, jadi tidak berpusat ke salah satu ISP agar trafik dapat berjalan optimal, memaksimalkan throughput, memperkecil waktu tanggap dan menghindari overload pada salah satu jalur koneksi, teknologi itulah yang disebut Load balancing. Untuk diterapkan teknik Load balancing yang bisa mendistribusi beban kepada sebuah service yang ada pada server dengan memanfaatkan metode distribusi dua line koneksi yang disebut dengan metode NTH. Nantinya mikrotik diharapkan mampu mengoptimalkan bandwidth pada tiap client yang akan koneksi ke internet. Akan diterapkan juga Teknik failover pada jaringan ini, yaitu jika salah satu koneksi gateway sedang terputus maka gateway yang lainnya otomatis akan menopang semua traffic jaringan. Akan dibuat juga menejemen bandwith disemua client, agar pendistribusian bandwith merata. AbstractThe development of computer networks and internet so rapidly at the present time, particularly on the Internet as information media of course must have good connection quality. So also found on the PT.Gojek Indonesian who has used two ISP. When many requests from users, the network devices will be burdened because they have to do a lot of service processes for requests from users. The solution is to divide the traffic load that comes to network devices, so that it is not centered on one ISP so that traffic can run optimally, maximize throughput, minimize response time and avoid overloading one of the connection lines, that technology is called Load balancing. Load balancing techniques are applied to distribute the load against a service that is on the server by utilizing the two connection path distribution method called the Nth method. Later, the proxy hopes to be able to optimize the bandwidth for each client that will connect to the internet. Will also be implemented failover technique on this network, that is if one of the gateway connections is being interrupted then the other gateway will automatically support all network traffic. Will also create bandwidth management for all clients, so that bandwidth distribution is evenly distributed.
Penerapan Data Mining Menggunakan Algoritma Apriori untuk Menentukan Pola Penyebab Gelandangan dan Pengemis
Authors: Agustin Wirta , Muharmi Yulya
Published: June 2020

Gelandangan dan pengemis salah satu masalah yang ada di daerah perkotaan, karena dapat mengganggu ketertiban umum, keamanan, stabilitas dan pembangunan kota. Upaya yang dilakukan saat ini masih fokus pada cara penanganan gelandangan dan pengemis, belum untuk pencegahan. Salah satu cara yang bisa dilakukan adalah dengan menentukan pola usia gelandangan dan pengemis. Algoritma Apriori sebuah metode Association Rule dalam data mining untuk menentukan frequent itemset yang berfungsi membantu menemukan pola dalam sebuah data (frequent pattern mining). Perhitungan manual menggunakan algoritma apriori, menghasilkan pola kombinasi sebanyak 3 rules dengan nilai minimum support sebesar 30% dan nilai confidence tertinggi sebesar 100%. Pengujian penerapan Algoritma Apriori menggunakan aplikasi RapidMiner. RapidMiner salah satu software pengolahan data mining, diantaranya analisis teks, mengekstrak pola-pola dari data set dan mengkombinasikannya dengan metode statistika, kecerdasan buatan, dan database untuk mendapatkan informasi bermutu tinggi dari data yang diolah. Hasil pengujian menunjukkan perbandingan pola usia gelandangan dan pengemis yang berpotensi menjadi gelandangan dan pengemis. Berdasarkan hasil pengujian aplikasi RapidMiner dan hasil perhitungan manual Algoritma Apriori, dapat disimpulkan sesuai kriteria pengujian, bahiwa pola (rules) usia dan nilai confidence (c) hasil perhitungan manual Algoritma Apriori tidak mendekati nilai hasil pengujian menggunakan aplikasi RapidMiner, maka tingkat keakuratan pengujian rendah, yaitu 37.5 %.

 

Abstract

 

Homeless and beggars are one of the problems in urban areas as they possibly disrupt public order, security, stability and urban development. The efforts conducted are still focusing on managing the existing homeless and beggars instead of preventing the potential ones. One of the methods used for solving this problem is Algoritma Apriori which determines the age pattern of homeless and beggars. Apriori Algorithm is an Association Rule method in data mining to determine frequent item set that serves to help in finding patterns in a data (frequent pattern mining). The manual calculation through Apriori Algorithm obtains combination pattern of 3 rules with a minimum support value of 30% and the highest confidence value of 100%. These patterns were refences for the incharged department in precaution action of homeless and beggars arising numbers. Apriori Algorithm testing uses the RapidMiner application which is one of data mining processing software, including text analysis, extracting patterns from data sets and combining them with statistical methods, artificial intelligence, and databases to obtain high quality information from processed data. Based on the results of the said testing, it can be concluded that the level of accuracy test is low, i.e. 37.5%.
Sistem Keamanan Multi Mail Server dengan Teknik Enkripsi OPENPGP pada Zimbra Exchange Open Source Software
Authors: Faruq Amrul , Khaeruddin Khaeruddin , Lestandy Merinda
Published: June 2020

Surat elektronik atau email merupakan media komunikasi yang sangat populer. Untuk mengirim dan menerima email, diperlukan sebuah penyedia (server) yang di dalamnya terdapat layanan email. Zimbra Collaboration Suite (ZCS) merupakan salah satu aplikasi mail server powerfull yang dapat dipergunakan sebagai aplikasi mail server dalam jumlah user puluhan hingga ribuan. Pada penelitian ini, sistem enkripsi pada Zimbra multiple-mail server menggunakan metode OpenPGP  diimplementasikan untuk mengamankan isi email yang dikirim maupun yang diterima, yaitu dengan memanfaatkan public key dan private key. Hasil pengujian menunjukkan metode OpenPGP  mampu bekerja dengan baik untuk keamanan sistem pengiriman dan atau penerimaan email pada multi mail server.

 

Abstract

Electronic mail or e-mail is a very popular communication medium. To send and receive e-mails, a provider (server) is needed in which there is an e-mail service. Zimbra Collaboration Suite (ZCS) is one powerful mail server application that can be used as a mail server application in the number of users from tens to thousands. In this study, the encryption system on the Zimbra multiple-mail server uses the OpenPGP  method to be implemented to secure the contents of e-mails sent and received, namely by using the public key and private key. The test results show that the OpenPGP  method works well for the security of the email sending/receiving system on a multi-mail server.
Rancang Bangun Case Based Reasoning untuk Diagnosis Hama dan Penyakit Tanaman Nilam menggunakan Nearest Neighbor Kombinasi Certainty Factor
Authors: Adawiyah Rabiah , Handayani Fitrianti
Published: June 2020

Tanaman nilam menghasilkan minyak nilam (patchouli oil) yang digunakan sebagai bahan baku kosmetik, parfum, antiseptik, sabun, obat, dan insektisida. Dalam pengembangan dan peningkatannya tanaman nilam mengalami beberapa kendala seperti serangan hama dan penyakit yang mengakibatkan rendahnya hasil panen khususnya pada daerah Desa Gunung Sari Kecamatan Watubangga Kabupaten Kolaka. Pengembangan tanaman nilam yang terserang hama dan penyakit seringkali terhambat karena masih banyak petani yang tidak mengetahui jenis hama dan penyakit yang menyerang tanaman petani. Oleh sebab itu sistem pakar berbasis kasus atau Case Based Reasoning (CBR) dibangun untuk mendiagnosis jenis hama dan penyakit tanaman nilam. Pada penelitian ini digunakan 7 jenis penyakit dan 22 gejala berdasarkan studi kasus tempat penelitian. CBR menggunakan metode similarity Nearest Neighbor untuk menemukan kemiripan antar kasus yang berada dalam tahapan retrieve. Pada penelitian ini digunakan juga metode lain yaitu Certainty Factor yang berfungsi untuk mengetahui derajat kepercayaan terhadap hasil diagnosis sistem dalam menghasikan jenis hama dan penyakit tanaman nilam. Berdasarkan hasil penelitian dengan menggunakan kombinasi dua metode Nearest Neighbor dan Certainty factor maka dihasilkan sistem mampu melakukan diagnosis hama dan penyakit tanaman nilam dengan nilai similarity 0.7 dan tingkat kepercayaaan sebesar 97,2 %  serta menghasilkan tingkat akurasi sistem sebesar 93.82 % dan tingkat kesalahan sistem 3 % AbstractPatchouli oil is used as a raw material for cosmetics, perfumes, antiseptics, soaps, medicines, and insecticides. In the development and improvement of patchouli plants experienced several obstacles such as pests and diseases which resulted in low yields, especially in the area of Gunung Sari Village, Watubangga District, Kolaka Regency. The development of patchouli plants attacked by pests and diseases is often hampered because there are still many farmers who do not know the types of pests and diseases that attack farmers' crops. Therefore a case based reasoning (CBR) expert system was built to diagnose patchouli plants and pests. In this study 7 types of diseases were used and 22 symptoms were based on the case study site. CBR uses the similarity Nearest Neighbor method to find similarities between cases that are in the retrieval stage. In this study, another method is used, namely Certainty Factor, which functions to determine the degree of trust in the results of system diagnosis in producing patchouli species and diseases. Based on the results of the study by using a combination of the two Nearest Neighbor and Certainty factor methods, the system was able to diagnose patchouli pests and diseases with a similarity value of 0.7 and a confidence level of 97.2% and produce a system accuracy rate of 93.82% and a system error rate of 3%
Akuisisi Foreground dan Background Berbasis Fitur DTC pada Matting Citra secara Otomatis
Authors: Koeshardianto Meidya , Yuniarno Eko Mulyanto , Hariadi Mochamad
Published: June 2020

Teknik pemisahan foreground dari background pada citra statis merupakan penelitian yang sangat diperlukan dalam computer vision. Teknik yang sering digunakan adalah image segmentation, namun hasil ekstraksinya masih kurang akurat. Image matting menjadi salah satu solusi untuk memperbaiki hasil dari image segmentation. Pada metode supervised, image matting membutuhkan scribbles atau trimap sebagai constraint yang berfungsi untuk melabeli daerah tersebut adalah foreground atau background. Pada makalah ini dibangun metode unsupervised dengan mengakuisisi foreground dan background sebagai constraint secara otomatis. Akuisisi background ditentukan dari varian nilai fitur DCT (Discrete Cosinus Transform) yang dikelompokkan menggunakan algoritme k-means. Untuk mengakuisisi foreground ditentukan dari subset hasil klaster fitur DCT dengan fitur edge detection. Hasil dari proses akuisisi foreground dan background tersebut dijadikan sebagai constraint. Perbedaan hasil dari penelitian diukur menggunakan MAE (Mean Absolute Error) dibandingkan dengan metode supervised matting maupun dengan metode unsupervised matting lainnya. Skor MAE dari hasil eksperimen menunjukkan bahwa nilai alpha matte yang dihasilkan mempunyai perbedaan 0,0336 serta selisih waktu proses 0,4 detik dibandingkan metode supervised matting. Seluruh data citra berasal dari citra yang telah digunakan para peneliti sebelumnyaAbstractThe technique of separating the foreground and the background from a still image is widely used in computer vision. Current research in this technique is image segmentation. However, the result of its extraction is considered inaccurate. Furthermore, image matting is one solution to improve the effect of image segmentation. Mostly, the matting process used scribbles or trimap as a constraint, which is done manually as called a supervised method. The contribution offered in this paper lies in the acquisition of foreground and background that will be used to build constraints automatically. Background acquisition is determined from the variant value of the DCT feature that is clustered using the k-means algorithm. Foreground acquisition is determined by a subset resulting from clustering DCT values with edge detection features. The results of the two stages will be used as an automatic constraint method. The success of the proposed method, the constraint will be used in the supervised matting method. The difference in results from In the research experiment was measured using MAE (Mean Absolute Error) compared with the supervised matting method and with other unsupervised matting methods. The MAE score from the experimental results shows that the alpha matte value produced has a difference of 0.336, and the difference in processing time is 0.4 seconds compared to the supervised matting method. All image data comes from images that have been used by previous researchers.
In Silico Rationalisation of Selectivity and Reactivity in Pd-Catalysed C-H Activation Reactions
Authors: Cao Liwei , Kabeshov Mikhail , Ley Steve , Lapkin Alexei
Published: June 2020

A computational approach has been developed to automatically generate and analyse the structures of the intermediates of palladium catalysed carbon-hydrogen (C-H) activation reactions as well as to predict the final products. Implemented as a high-performance computing cluster tool, it has been shown to correctly choose the mechanism and rationalise regioselectivity of chosen examples from open literature reports. The developed methodology is capable of predicting reactivity of various substrates by differentiation between two major mechanisms - proton abstraction and the electrophilic aromatic substitution. An attempt has been made to predict new C-H activation reactions. This methodology can also be used for the automated reaction planning, as well as a starting point for microkinetic modelling.
A Ligand-Directed Nitrophenol Carbonate for Time-Dependent Imidazoquinoline Delivery
Authors: Burt Anthony J. , Ahmadvand Parvaneh , Opp Larissa K. , Kang ChulHee , Mancini Rock
Published: June 2020

To our knowledge we are the first to utilize ligand-directed proximity accelerated bioconjugation chemistry to deliver a therapeutic payload. Here we report a new chemical moiety based on nitrophenol carbonates for ligand-directed in situ labeling of avidin with an immunostimulant prodrug. This renders avidin a depot for time-dependent release of bioavailable immunostimulant following hydrolysis and self-immolation of the transient modification. Structural biology was utilized to verify the binding pose of the modified biotin directing group and offer insight into nucleophilic residues proximal to the nitrophenol carbonate. Time-dependent release of the immunostimulant was monitored with an immune cell line to demonstrate the release of bioavailable immunostimulant over 48 h. We show that this scaffold warrants further investigation for the time-dependent delivery of therapeutics and further investigation of protein ligand pairs beyond biotin and avidin used for this work
Interactions between Ultrastable Na4Ag44(SR)30 Nanoclusters and Coordinating Solvents: Uncovering the Atomic-scale Mechanism
Authors: Chevrier Daniel M. , Conn Brian E. , Li Bo , Jiang De-En , Bigioni Terry P. , Chatt Amares , Zhang Peng
Published: June 2020

We report the mechanism on the ultrahigh stability of Na4Ag44(SR)30 by uncovering how coordinating solvents interact with the Na4Ag44(SR)30 nanocluster at the atomic scale. Through synchrotron X-ray experiments and theoretical calculations, it was found that strongly coordinating aprotic solvents interact with surface Ag atoms, particularly between ligand bundles, which compresses the Ag core and relaxes surface metal-ligand interactions. Furthermore, water was used as a cosolvent to demonstrate that semi-aqueous conditions play an important role in protecting exposed surface regions and can further influence the local structure of the silver nanocluster itself. Notably, under semi-aqueous conditions, aprotic coordinating solvent molecules preferentially remain on the metal surface while water molecules interact with ligands, and ligand bundling persisted across the varied solvation conditions.
Influence of Solar Activity on Water Clusters. Annual Variations 2015-2019
Authors: Shevchenko Igor
Published: June 2020

The variations of solar activity and distribution of solar energy due to the rotation of the Earth around its axis and around the Sun exert a strong influence on water clusters, as a result of which their chemical reactivity in hydrolytic processes can vary in a very wide range. This phenomenon is well manifested in the hydrolysis of the phosphoric acid esters. 5-Year regular investigations (2015-2019) of the hydrolysis of triethylphosphite in acetonitrile show that the rate of this reaction with all other conditions being equal displays diurnal and annual variations, and is also modulated by the 11-year cycles of solar activity.
Multi-fidelity Statistical Machine Learning for Molecular Crystal Structure Prediction
Authors: Egorova Olga , Hafizi Roohollah , Woods David C. , Day Graeme
Published: June 2020

The prediction of crystal structures from first principles requires highly accurate energies for large numbers of putative crystal structures. The accuracy of solid state density functional theory (DFT) calculations is often required, but hundreds or more structures can be present in the low energy region of interest, so that the associated computational costs are prohibitive. Here, we apply statistical machine learning to predict expensive hybrid functional DFT (PBE0) calculations using a multi-fidelity approach to re-evalute the energies of crystal structures predicted with an inexpensive force field. The method uses an autoregressive Gaussian process, making use of less expensive GGA DFT (PBE) calculations to bridge the gap between the force field and PBE0 energies. The method is benchmarked on the crystal structure landscapes of three small, hydrogen bonding organic molecules and shown to produce accurate predictions of energies and crystal structure ranking using small numbers of the most expensive calculations; the PBE0 energies can be predicted with errors of less than 1 kJ/mol with between 4.2-6.8% of the cost of the full calculations. As the model that we have developed is probabilistic, we discuss how the uncertainties in predicted energies impact on assessment of the energetic ranking of crystal structures.
In Silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential Therapeutic Targets for Drug Repurposing Against COVID-19
Authors: López-Cortés Andrés , Guevara-Ramírez Patricia , Kyriakidis Nikolaos C , Barba-Ostria Carlos , Cáceres Ángela León , Guerrero Santiago , Munteanu Cristian Robert , Tejera Eduardo , Ortiz-Prado Esteban , Cevallos-Robalino Doménica , Gómez J. Ana María , Simbaña-Rivera Katherine , Granizo-Martínez Adriana , Pérez-M Gabriela , García-Cárdenas Jennyfer M. , Zambrano Ana Karina , Moreno Silvana , Pérez-Castillo Yunierkis , Cabrera-Andrade Alejandro , Andrés Lourdes Puig San , Proaño-Castro Carolina , Bautista Jhomayra , Varela Nelson , Quiñones Luis Abel , Paz-y-Miño Cesar
Published: June 2020

There is pressing urgency to better understand the immunological underpinnings of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus clade 2 (SARS-CoV-2) in order to identify potential therapeutic targets and drugs that allow treating patients effectively. To fill in this gap, we performed in silico analyses of immune system protein interactome network, single-cell RNA sequencing of human tissues, and artificial neural networks to reveal potential therapeutic targets for drug repurposing against COVID-19. As results, the high-confidence protein interactome network was conformed by 1,588 nodes between immune system proteins and human proteins physically associated with SARS-CoV-2. Subsequently, we screened all these nodes in ACE2 and TMPRSS2 co-expressing cells according to the Alexandria Project, finding 75 potential therapeutic targets significantly overexpressed (Z score > 2) in nasal goblet secretory cells, lung type II pneumocytes, and ileal absorptive enterocytes of patients with several immunopathologies. Then, we performed fully connected deep neural networks to find the best multitask classification model to predict the activity of 10,672 drugs for 25 of the 75 aforementioned proteins. On one hand, we obtained 45 approved drugs, 16 compounds under investigation, and 35 experimental compounds with the highest area under the receiver operating characteristic (AUROCs) for 15 immune system proteins. On the other hand, we obtained 4 approved drugs, 9 compounds under investigation, and 16 experimental compounds with the highest multi-target affinities for 9 immune system proteins. In conclusion, computational structure-based drug discovery focused on immune system proteins is imperative to select potential drugs that, after being effectively analyzed in cell lines and clinical trials, these can be considered for treatment of complex symptoms of COVID-19 patients, and for co-therapies with drugs directly targeting SARS-CoV-2.
Stable Helicene Radicals: Synthesis, Structure, Physical Properties, and Photocatalysis
Authors: Shaikh Aslam , Hossain Md Mubarak , Moutet Jules , Veleta Jose M , bloch jan , Astashkin Andrei V. , Gianetti thomas
Published: June 2020

Stable organic radicals have gained considerable attention in the fields of catalysis and material sciences. In particular, helical molecules are of great interest in the development and application of novel organic radicals in optoelectronic and spintronic materials. Here we report the syntheses of highly stable neutral quinolinoacridine radicals by chemical reduction of their quinolinoacridinium cation analogs. The crystal structures of these [4]helicene radicals were determined by X-ray diffraction. Electron paramagnetic resonance (EPR) measurements, supported by density functional theory (DFT) calculations, indicate that the unpaired electron is mostly localized, showing more than 40% of spin density located at the central carbon of the [4]helicene radicals. Quantitative conversion from neutral radical to cation is observed upon exposure to air, monitored via UV-vis spectroscopy. The successful photoreductive dehalogenation of aryl halides occurs in the presence of 10 mol% of [4]helicene radical under blue light.