bluuebunny/crossref_metadata_2025 huggingface dataset:
A COMPARATIVE ANALYSIS OF ROBOTIC V/S CONVENTIONAL SURGERY FOR FIVE GASTROENTEROLOGICAL CONDITIONS: THE CASE OF AN AHMEDABAD-BASED HOSPITAL
Authors: Lavsi Shlok , Patel Bhavin
Published: August 2023

Purpose: This study investigates the difference in post-operative outcomes between patients who have undergone laparoscopic and robotic surgery for ve gastroenterological conditions at a prominent hospital in Ahmedabad, Gujarat, India, and whether the differences are affected by age. A retrospective chart Design/ methodology/ approach: analysis of 69 laparoscopic and robotic surgeries for ve different gastroenterological conditions (hernia, hiatus hernia, cholecystectomy, colon cancer and pancreatic cancer) performed at Zydus Hospitals Ahmedabad in 2023 was conducted. Operative outcomes analysed included operative time (in minutes) and length of stay (in days) which were compared across age using Student t-test and ANOVA. A noticeable difference is found in the mean Findings: operative time for robotic surgery (204.75 minutes) compared to laparoscopic surgery (170.18 minutes). The mean length of stay (in days) for robotic surgery patients was 6.11 days i.e., approximately 2 days more than that of patients with laparoscopic surgery (4.06 days). The difference in mean operative time between age groups is statistically signicant whereas the difference in the mean length of stay between age groups is not. Practical implications: The results suggest that promoting robotic surgery in India could be an effective approach for improving surgical outcomes for gastroenterological conditions. It also emphasises the need for ongoing professional development programmes to enhance surgical expertise in robotic surgery.
Deutsche Strafrechtsgeschichte
Authors: Steinberg Georg
Published: August 2023

Das Buch zeichnet die Wandlungen des Zusammenspiels zwischen Strafrecht und Gesellschaft vom Frühmittelalter bis 1990 nach. Akzentuiert wird das 20. Jahrhundert, namentlich das dem Terror unterstellte NS-Strafrecht, das sozialistische Umerziehungsstrafrecht der DDR und die bundesdeutsche NS-Aufarbeitung. Zielgruppe sind Jurastudierende sowie jeder interessierte Leser.
utb+: Begleitend zum Buch erhalten Leser:innen Gesetzestexte als digitales Zusatzmaterial.
Fully Decentralized Peer-to-Peer Community Grid with Dynamic and Congestion Pricing
Authors: Doan Hien , Kim Daehee , Huy Truong hoang bao , Kim Hongseok
Published: August 2023

Peer-to-peer (P2P) electricity markets enable prosumers to minimize their costs, which has been extensively studied in recent research. However, there are several challenges with P2P trading when physical network constraints are also included. Moreover, most studies use fixed prices for grid power prices without considering dynamic grid pricing, and equity for all participants. This policy may negatively affect the long-term development of the market if prosumers with low demand are not treated fairly. An initial step towards addressing these problems is the design of a new decentralized P2P electricity market with two dynamic grid pricing schemes that are determined by consumer demand. Futhermore, we consider a decentralized system with physical constraints for optimizing power flow in networks without compromising privacy. We propose a dynamic congestion price to effectively address congestion and then prove the convergence and global optimality of the proposed method. Our experiments show that P2P energy trade decreases generation cost of main grid by 56.9% compared with previous works. Consumers reduce grid trading by 57.3% while the social welfare of consumers is barely affected by the increase of grid price.
A escrita ensaísta e a formação continuada de professores pedagogos
Authors: Mometti Antonio Carlos
Published: August 2023

A formação de professores é uma das áreas da pesquisa educacional que mais vêm crescendo nos últimos três decênios. Um dos pontos de maior relevância, nesse âmbito, é o desenvolvimento de métodos direcionados para a melhoria do ensino, bem como à busca de novas formas de comunicar mais claramente suas ideias e pensamentos. À vista disso, este trabalho possui por objetivo apresentar um estudo de caso realizado com um grupo de professores pedagogos, a fim de investigar o potencial de argumentação desenvolvida na escrita ensaísta digital, com a utilização do recurso do ambiente virtual de aprendizagem. Além disso, buscou-se compreender as bases ideológicas que fundamentam os discursos enunciados pelos professores acerca da escrita ensaísta e do seu potencial como metodologia para formação continuada docente. Para tanto, utilizamo-nos da análise discursiva mediante a perspectiva francesa, a qual evidenciou-nos os seguintes resultados: (i) o sentimento de medo, angústia e pânico operaram como base ideológica para o discurso dos professores, (ii) o estado de pandemia permitiu descobertas de recursos pedagógicos inovadores para a escrita, e (iii) os meios digitais possibilitam maior interação, tempo de planejamento e estudo.
Ações de educação ambiental da Secretaria Municipal do Meio Ambiente
Authors: Campelo de Sousa Dra. Camila , Kistemacher Dilmar , Alves da Silva Guilherme , De Almeida Alves Iramar
Published: August 2023

As transformações produzidas sobre o mundo natural, o aumento populacional e a degradação ambiental se constituem em desafios para a política ambiental. Dessa última, importa pensarmos como tem sido desenvolvida a educação ambiental. Estainvestigação objetivou conhecer as ações de educação ambiental não formal desenvolvidas pela Secretaria Municipal do Meio Ambiente do município de Codó (MA). A partir dos dados coletados via entrevistas, foi possível verificar que a Secretaria desenvolve projetos que visam minimizar os problemas ambientais, a exemplo da arborização de avenidas, do reflorestamento na margem de rios e da produção e distribuição de mudas para a comunidade. Podemos afirmar que a gestão tem realizado ações ambientais, mas ainda apresenta limitações.
Difficulties in learning Arabic among contemporary orientalists: plural taksir as a model
Authors: البُديري رياض كريم , حسن عبد الحسن عباس
Published: August 2023

The researcher would like to add three observations about the difficulties that Orientalists mention about Arabic:
The first: Among the aforementioned difficulties are not encountered by a native speaker of the Arabic language, so that difficulty becomes related to the methods of teaching it or to the methods of presentation, not to its linguistic system.
Language and its rules
Taha Hussein and Ihsan Abbas's points of view on Nahj al-Balaghah and their criticism
Authors: خانی علی , نیا أمیر فرهنگ
Published: August 2023

Nahj al-Balaghah, as a religious book and an important source for the Shiites, was not a collection of sermons, letters, sermons, wisdom and etiquette of Imam Ali (A) - which was collected by Sharif al-Radi and named it with this title - far from the doubts of the skeptics about its validity and the suspicions of those who doubted about its authenticity and the validity of its authority and its sources. And the legislator of eloquence And its source and origin of rhetoric and its birth, and from it (A) appeared its foundations and from it its laws were taken and on its examples the example of a preacher, and in its words every eloquent preacher sought help and dialed in it the tongue of every eloquent Arab. This is and that among the great ones who took the method of rhetoric and criticized it, is Taha Hussein, and he is influenced by the Cartesian school of thought, which is characterized by doubt.
The concept of divine beauty and adoration in Plotinus' moral philosophy
Authors: المعلة جميل حليل , البو كلل دعاء راهي
Published: August 2023

Likewise, Plotinus saw that goodness is the highest degree of beauty, and that beauty is goodness, and it must be present in the one (the first), and it is issued directly to the mind, and from the mind to the soul. The ultimate goal for all people is to reach the highest degrees of beauty. Goodness and beauty are linked together and inseparable, as they are associated with religious rituals. Reaching religious purification is achieving goodness and beauty.
Aesthetic geometry in semantic differences (a study and analysis of the Quranic semantic differences as a model)
Authors: عبد الرضا عطاشي عبد الرضا عطاشي
Published: August 2023

Conceptually similar terms in the Holy Qur’an since ancient times have become a rich topic for delving into the rug of linguistic studies between linguists and interpreters. Based on these linguistic studies, the veil has been revealed about the aesthetic engineering that the Arabic language embodied in the Holy Qur’an enjoys, and what the word in the text enjoys from a meaning and conceptual field that resolves the independence of its meaning from the word that it imagines to share in the meaning in the Holy Qur’an
The stylistics of the lamentation of Imam Al-Hussein (PBUH) (a stylistic comparison between the poems of Al-Sharif Al-Radi and Ali bin Isa Al-Irbili)
Authors: شاملي نصر الله , أحمدي سيدة رقية , حسنعليان سمية
Published: August 2023

Imam Al-Hussein (A) - especially after the incident of Al-Taff - became the subject of interest for many poets. They made the issue of his martyrdom the focus of their poetry, praising the imam's virtues and virtues, lamenting him with pure emotions. Poetry committed to the love of Ahl al-Bayt (G) began to carry echoes of the incident, and among these poets are Ali bin Isa al-Arbili and al-Sharif al-Radi.
On the other hand, one of the recent critical studies through which the aesthetics of the text appears is comparative stylistics, as literature is considered a more specific use of the language, which has more specific methods, which made it a developed linguistic world in which there is beauty that fascinates the reader; The stylistic vision is what is meant by this manifestation of beauty in the language.
Evaluation of urban land uses in the ancient city of Kufa
Authors: الياسري وهاب فهد , البوعربي نهى نعمة
Published: August 2023

The study shed light on the reality of the state of urban land uses in the ancient city of Kufa and the most important factors influencing it, and then evaluating those uses according to local planning standards represented by the criterion of per capita share as well as other criteria. Planning standards and population size, as there is a clear shortage in the number of housing units and housing space, as is the case in other uses such as transportation, industry, etc.
A number of conclusions have been reached, which is the final outcome through the final study of the land uses of this city
Abi Hayyan's choices in grammatical issues
Authors: الحريزي عائد كريم , البيضاني عبد الجواد عبد الحسن
Published: August 2023

Abu Hayyan distinguished himself from the grammarians that he directs the grammatical rule in the manner of his own vision, after enumerating the opinions in it, then declaring his doctrine in it, and then dealing with the distant opinions with criticism or belittlement. Rather, it is a choice from among the opinions put forward, to which the grammarians preceded it, so he chose the most correct of them.
Marketing of Brush-Tailed Porcupine (Atherurure africanus) Meat in Côte d'Ivoire, Characterization of Sellers and Profitability of Trade in Abidjan
Authors: Thierry Kouassi Konan , Moussa Kimsé , Noel Yapi Jean , Sidiki Sangaré , Seraphin Kouame Konan
Published: August 2023

The aim of this work was to characterize brush-tailed porcupine or African atherure (Atherurus africanus) meat trade in the markets of Abidjan District. The study was conducted between February 2021 and January 2022. The data were collected with 46 seller in three markets of Abidjan. These were “Marché Gouro de Yopougon” market (MGY), “marché Gouro d'Adjamé” market (MGA) and “Marché Abobo Gare” market (GA). Visits and interviews were carried out at morning each week. Results showed that all sellers in 3 markets were female and Ivorian (100%). These sellers came from four cultural groups. Akan Group represented more than half of sellers (54%). They were 26%, 44% and 50% higher than Gouro, Krou and Mandé group respectively (P ˂ 0.01). Merchants aged from 18 to 61 years. Sellers aged from 25 to 40 were 54.35%. This rate was 24 and 39% higher than 18-25 and >40 age respectively (P ˂0.01). Unmarried vendors were about 3 times higher than married ones (72% vs 28%; P = 0.01). A rate of 52% of atherure meat traders had never been to school. They were 30% higher than those who completed primary school in Côte d'Ivoire (P ˂ 0.01). They were also 39% more numerous than those who had completed high school and university. Atherure’s trade had generated a turnover of 189 million for 9000 carcasses sold. This meat was the most sold after the grasscutter. None animals were farmed. They were poached. Most of animals (28.4%) came from the forest area of Lôh-Djiboua region.
A Critical Analysis of Symbolism in Modernist Literature with reference to T.S. Eliot and Roland Barthes
Authors: Abbar Emad Mohammad
Published: August 2023

This study aims to conduct a critical analysis of symbolism in modernist literature, with specific reference to the works of T.S. Eliot and Roland Barthes. The objectives of the study are to identify the key symbols employed by these authors, explore their significance within the context of modernist literature, and examine the underlying themes and messages conveyed through these symbols. The methodology of the study involves a comprehensive literature review of relevant scholarly articles, books, and primary sources related to modernist literature, symbolism, and the selected authors' works. The analysis will be conducted through close reading and textual analysis of specific poems and writings by T.S. Eliot and Roland Barthes, focusing on their symbolic elements and their connections to broader social, cultural, and philosophical contexts. The problem statement of this study addresses the need to understand the deeper layers of meaning and significance in modernist literature, particularly with regards to the role of symbolism. By unraveling the layers of symbolism in the works of T.S. Eliot and Roland Barthes, this research aims to shed light on the complexities and nuances of modernist literature, and contribute to a deeper understanding of its artistic and intellectual foundations. The results and discussions of this study anticipate uncovering the intricate symbolic network embedded in the selected authors' works, revealing the multiple layers of meaning and the interplay between symbols and their socio-cultural context. Furthermore, the study aims to identify recurring themes and motifs across their writings, highlighting the distinct approaches to symbolism employed by each author. In conclusion, this study seeks to provide a critical analysis of symbolism in modernist literature, specifically examining the works of T.S. Eliot and Roland Barthes. By exploring the symbols, themes, and underlying messages in their writings, this research aims to contribute to a deeper appreciation and understanding of modernist literature as a significant literary and artistic movement. The findings of this study will not only enhance the scholarly discourse surrounding these authors but also offer valuable insights into the broader field of literary symbolism and its relevance in modernist literature.
An Assessment of the Gains and Pains of Western Democracy in Nigeria Since 1999
Authors: Bello Mas’ud , Ibrahim Sani
Published: August 2023

Since the return to democratic governance in Nigeria in 1999, the country has witnessed several upheavals and topsy-turvy attempts toward improving people-centered democratic governance and leadership management in Nigeria. The challenges revolve around violation of the rule of law, abuse of fundamental human rights, electoral malpractices, injustice and impunity, corruption, terrorism, political instability, budgetary distortions, poor provision of infrastructural social amenities, unemployment and grinding abject poverty. Due to these numerous challenges, most scholars are skeptical about the success of democracy in Nigeria. Therefore, to understand whether or not the practice of Western democracy is a success story in Nigeria, this paper is structured into the meaning and principles or features of democracy, the success of Western democracy and its failures, and the way forward. The methodologies for data collection were library research and reviews. Qualitative primary data were accessed and used. The findings revealed that while there are gains in democracy, the pains and or failure outweigh the success.
The Effect of Islamic Work Ethics and Knowledge Sharing Behaviour and Organization Citizenship Behaviour and Its Impact on IMFIs Employee Performance (A Study on BMT and Kubu Raya Cooperative and Pontianak City)
Authors: Hafidloh Hafidloh , Rosnani Titik , Daud Ilzar , Fauzan Rizky
Published: August 2023

This study aims to investigate the effect of Islamic work ethics and knowledge sharing behavior to organizational citizenship behavior and its impact on employee performance. The study uses two-stage sampling – purposive sampling and simple random sampling. The data is analyzed using structural equation modelling (SEM) AMOS 21. The study shows that Islamic work ethics has a significant effect on organizational citizenship behavior; whereas it does not have a significant effect on IMFIs employee performance. Knowledge sharing behavior affects significantly to IMFIs employee performance; however, it does not contribute significant effect on organizational citizen behavior. Organization citizenship behavior has a significant effect on employee performance.
My Husband, Please Make me your Wife to live on the Better Position from now on! (Tcheonzamun 017th-032nd)
Authors: Kim Sangdeog Augustin
Published: August 2023

French missionary Dallet (1874) wrote about ‘The thousand character essay’ in his book. In Korea, ‘The thousand character essay’ is called as Tcheonzamun. The present researcher tried to translate this Tcheonzamun (The thousand character essay) poem (Tcheonzamun 017th-032nd). Here in the present study, the first method (to translate through Korean pronunciation) was utilized. At present study, a Tcheonzamun book written by Han (1583) was utilized. The title of this manuscript is ‘my husband, please make me your wife to live on the better position from now on!’ It is the first translation of the poem of ‘The thousand character essay’ (Tcheonzamun 017th-032nd). <Number in Tcheonzamun Chinese characters (the pronunciation on Korean language and written in English alphabet) Transformed phrase on Korean pronunciation in Korean alphabet (Transformed phrase on Korean pronunciation in English alphabet)> 017-020 寒 (Han) 來 (Lae) 暑 (Seo) 往 (Wang) 이래서야! (I lae seo ya) It is not good! My husband, you must change the present unhappy condition of your wife! 021-024 秋 (Tchu) 收 (Su) 冬 (Dong) 藏 (Zang) 추스르자! (Tchu su leu za) My husband, please, make better this bad condition of your wife! 025-028 閏 (Yun) 餘 (Yeo) 成 (Seong) 歲 (Se) 눌려 사네! (Null yeo sa ne!) Now I am deeply pressed by you, my husband! 029-032 律 (Yul) 呂 (Yeo) 調 (Zo) 陽 (Yang) 올려줘야! (Ol lyeo zwo ya) My husband, please make me your wife to live on the better position from now on!
My Husband, there are Two Selections for you! Do you want to be Miserable as Shown in (025-028)? Or do you wish to be Happy as Shown in (029-032)? (Tcheonzamun 017th-032nd)
Authors: Kim Sangdeog Augustin
Published: August 2023

French missionary Dallet (1874) wrote in his book that ‘The thousand character essay’ had been utilized as a textbook for instructing Chinese character for the children in old China. ‘The thousand character essay’ is called as ‘Tcheonzamun’ in Korea. The present researcher chose 16 Chinese letters, and those 16 letters composed a poem of ‘The thousand character essay’ (Tcheonzamun 017th-032nd). For example, <017-020 寒 (Han) 來 (Lae) 暑 (Seo) 往 (Wang)> is a line. The present researcher used two translating methods. The first one is to utilize Korean pronunciation of Chinese character, and the second one is to use the meaning of Chinese character. There is another one method. It is to delete same part(s) of a Chinese character on the same line. At present, the researcher translated this poem through the second method. The book of Tcheonzamun by Han (1583) was taken as a textbook for this study. The title of this manuscript is ‘My husband, there are two selections for you! Do you want to be miserable as shown in (025-028)? Or do you wish to be happy as shown in (029-032)?’ The result of this study on the poem of ’The thousand character essay’, (Tcheonzamun 017th-032nd) was described as follows.  017-020 寒 (Han) 來 (Lae)-土=小人 暑 (Seo) 往 (Wang)-土=彳人 It is well known, the next phrase. "In order to give the warm condition (暑) to the slow walker (to the husband) (彳人), the smaller person (the wife) must have the cold condition (寒)." 021-024 秋 (Tchu) 收 (Su) 冬 (Dong) 藏 (Zang) But, this saying it is not true. It is not right! My dear Darling My husband! If you want to take (收) the best thing in your whole life (秋), you must do the good behavior (藏) to me your wife in common days, especially in the difficult time (冬) for me your wife! My husband, there are two selections for you! Do you want to be miserable as shown in (025-028)? Or do you wish to be happy as shown in (029-032)? 025-028 閏 (Yun) 餘 (Yeo) 成 (Seong)-戈=刀 歲 (Se)-戈=山广小 My husband! Even though you are the rich man (餘), if you scold (刀) your wife (小) in your house (广) and in the outdoors (山), you might soon be the poor man (閏). 029-032 律 (Yul)-聿=彳 呂 (Yeo)-口-口=丶 調 (Zo) -口-口-亠-二-土=几 陽 (Yang) My husband! Do you want the splendid thing like the shooting star (丶) to occur to you the slow walker (彳)? I am your wife, and I am shining like the sun (陽), while you are the man who has nothing (几). My husband, I can make you with my sincere love to be the happiest person in this world!
Effect of Alum on Microbial Load of Well Water from Rural and Urban Areas in Enugu State
Authors: Jacinta Aneke Chinwe , Jaluchimike Iloputaife Emmanuel , Ngozi Ewoh Anthonia
Published: August 2023

Ten well water samples were analyzed for the development of bacterial load using 1%, 5% and 10% concentrations of alum which was added to each 100ml of well water samples to determine the effect of alum on the microbial load of well water from Rural and Urban Areas in Enugu State. After exerting an effect on the well water sample, the supernatants and sediments were analyzed for development of bacteria colonies by viable cell counts. It was observed that the effect of alum on bacterial load increases as the percentage concentration of the of alum increases, however, further increase in the concentration of alum has no effect on the bacterial load, and this can be observed in well water from Ufuma Achara layout, Agbani Nkanu, Ugbo Paul Abakpa, Ohofia Uwani and Amodu Awkunanaw. On the other hand, from1% to 5% concentration of alum has no effect on the supernatant of well water from Amaokwe Achara layout, but however, with increase in concentration of about 10% it began to exert an effect on the bacterial load of both the supernatants and sediments.
Iron Oxide Nanoparticles as Anti-Virulence Factors of Gram-positive and Gram-negative Bacteria
Authors: Al-Rawi Marwa amin , Al-Mudallal Nada H. A. L. , Taha Ali A.
Published: August 2023

Background: Due to their extensive use in medical therapy, iron oxide nanoparticles have recently attracted the attention of researchers in the field of increasing multi-resistance properties in bacterial pathogens. Because iron oxide nanoparticles have a high specific surface area, they can interact with bacterial surface structures and exhibit significant antibacterial activity. Objective: The current work, determined the effect of a novel anti-virulence factor agent which was created from iron oxide nanoparticles against selected gram-positive and gram-negative variant bacterial strains that were isolated and identified from elderly Iraqi patients with urinary tract infections. Methods: Seven bacterial strains (three gram-positive and four gram-negative) were tested for their (biofilm, adhesion, and hemolysis) activity using the quantitative test-tube method, glass-slide method, and by determining the hemolysis ability of bacterial isolates against previously prepared RBC, respectively. The highest virulence factors formation bacterial isolates were chosen to determine the effect of Iron-oxide nanoparticles. Previously prepared and characterized Iron- oxide nanoparticles were used as anti- (biofilm, adhesion, and hemolysis) by using specific Bacterial-Fe3O4 NPs complex with different concentrations. The Results: All these bacteria expressed their virulence factors, the highest-level biofilm formation abilities were detected in Proteus mirabilis and Staphylococcus aureus, and the highest-level adhesion activity was observed in Enterococcus faecalis and Pseudomonas aeruginosa while the highest-level hemolysis activities on human RBC were determined in Micrococcus luteus and E. coli. The effects of (Fe3O4) nanoparticles against the highest virulence factors bacterial isolates shows an increases in the biofilm formation abilities of S. aureus and P. mirabilis as well as for standard bacterial strains the anti-biofilm formation ability of (Fe3 O4) NPs against gram-positive S. aureus, Proteus mirabilis, and standard gram-negative bacteria demonstrated an in-decrease biofilm formation ability of these bacteria effective at (5000 and 10000 µg/ml). The anti-adhesion ability of (Fe3 O4) NPs against gram-positive Enterococcus faecalis, and gram-negative Pseudomonas aeruginosa determined no effect on the adhesion abilities of gram-positive and negative bacteria atall concentrations (250, 400, 500, 750 and 1000µg/ml) Finally, the effect of different concentrations of iron oxide nanoparticles on the hemolysis ability of Micrococcus luteus and Escherichia coli on RBC was determined, the highest hemolysis inhibition level was estimated in 1000 µg/ml and the less inhibition in 500 µg/ml as compared with control.
The Vast World of the Science of Schizophrenia, the Immense Trials and Tribulations of Life and the Vast and Visionary Future
Authors: Palit Sukanchan
Published: August 2023

Today is the world of scientific and technological innovations in the field of medical science. Schizophrenia is a difficult ailment to treat. The author is suffering from schizophrenia for the last 30 years. Today since 2012 he is suffering from eye ailment and has glaucoma in his both eyes. The author lucidly and with cogent insight describes the agony and pain he experienced in the last 30 years. Today is the world of Fifth Industrial Revolution and application of United Nations Sustainable Development Goals. The vast world of the science of schizophrenia ailment needs to be re- envisioned and reframed as regards treatment and cure. Human sufferings and travails, trials and tribulations are immense for a mental patient suffering with this irrecoverable and monstrous ailment. Surely a new dawn in human civilization, man and mankind will emerge if doctors and medical health professionals takes active and positive steps in scientific research endeavor in the field of schizophrenia. The author deeply discusses these issues in this article. Science has advanced a lot since 1993 when the author was diagnosed with schizophrenia. The author deeply contemplates the need of psychology and psychiatry in the path towards a patient’s illness, treatment and revival.
Docetaxel, Cisplatin, Leucovorin and 5- Fluorouracil versus Leucovorin, 5-Fluorouracil, and Cisplatin as Neoadjuvant Chemotherapy Followed by Chemoradiation in Head and Neck Cancer
Authors: Majumder Rumana Afroz , Islam A.N.M. Mainul , Mannan Md. Abdul , Chowdhury Aditi Paul
Published: August 2023

Background: HNSCC is the fifth most common cancer in the world and one of the most prevalent cancers in Bangladesh. Despite significant improvement in radiotherapy, the high incidence of loco-regional recurrences is a major challenge for radiation oncologists. This study was done to compare the response and toxicity of Docetaxel, Cisplatin, Leucovorin and 5- Fluorouracil (TPLF) vs Leucovorin, 5- Fluorouracil, and Cisplatin (LFP) as neoadjuvant chemotherapy followed by concurrent chemo-radiation with Cisplatin in the treatment of locally advanced head and neck cancer of squamous cell carcinoma. Materials and Methods: This study was carried out among 60 patients of locally advanced of head and neck cancer at Khwaja Yunus Ali Medical College & Hospital, Sirajganj from January 2015 to December 2015. In Arm-A, 30 patients received three cycles of neoadjuvant chemotherapy with Docetaxel 75 mg/m2 on D1, Cisplatin 75 mg/m2 on D1, Leukovorine 30 mg on D1-D3, 5-Flourouracil 750 mg/m2 on D1-D5 and in Arm B 30 patients received neoadjuvant chemotherapy with Cisplatin 75 mg/m 2 on D1, Leucovorine 30 mg on D1-D3, 5-Flourouracil 750mg/m 2 on D1-D5 3 cycles with three weeks interval followed by concurrent chemoradiotherapy with 66 Gy in 33 fractions and weekly Cisplatin 40 mg/m 2 started on the first day of radiation. Results: Most of the patients were male and middle-aged group. In Arm-A, 21 patients (70%) showed complete response whereas in Arm-B regimen complete response was noticed in 16 patients (53.3%) which was statistically significant; however, partial responses were significantly more found in Arm-B. Regarding toxicity, with Arm-A patients experienced slightly more toxicities in comparison to Arm-B which was statistically non-significant. Conclusion: So, it could be concluded from this study that the therapeutic gain was better obtained in Arm-A compared to Arm-B in patients with locally advanced head and neck cancer.
A Comparative Study of the Effects of Yoga, Naturopathy, and Conventional Medical Treatment in Managing Low Back Pain
Authors: S Sindhu , S Karthick , K Selvakumar , K. Shivaprasad. , S. Sridevi.
Published: August 2023

Yoga, regarded as an art, science, and philosophy, encompasses various dimensions of human existence, including the physical, mental, and spiritual realms. Its potential for enhancing life's purpose and nobility is noteworthy. Patient expectations in the context of treatment outcomes, particularly for Complementary and Alternative Medicine (CAM) therapies, remain inadequately explored. This study aims to compare the effectiveness of three distinct interventions—Yoga, Naturopathy, and Conventional medical management—in alleviating pain, reducing disability, enhancing spinal mobility, and improving the quality of life in individuals with low back pain. Ninety participants were recruited based on the inclusion and exclusion criteria and randomly divided into three groups. The first group (group 1) received Yoga intervention, the second group (group 2) received Naturopathy treatments, and the third group served as the control (conventional medications). Visual Analogue Scale (VAS) scores, Oswestry Disability Index (ODI), Flexion Test-Finger to Floor Test (FTFT) results, and Quality of Life (QOL) were assessed at baseline and after a 10-day intervention period for all groups. Overall comparisons between the groups, utilizing ANOVA, revealed marked differences in pain severity, disability index, daily functional capacity, and Quality of Life (QoL) improvements following respective interventions. Substantial improvements were also noted within the yoga and naturopathic medicine groups across multiple variables.
Management of Inguinal Hernia in Adults in a Community Setting: The Case of the Commune I Reference Health Center of Bamako
Authors: I Diarra , KS Dembélé , B Ballo , B Karembé , C Tounkara , BM Dramé , M Sanogo , S Kassogué , O Tolo , S Konaté , B Keita , D Kanthé , O Koné , A Togo
Published: August 2023

The aim was to study and analyse the results of surgical treatment of inguinal hernia in a community setting. We conducted a prospective descriptive study from 1st January 2021 to 31 December 2021 in the general surgery department of the Commune I referral health centre. A total of 74 patients underwent surgery for inguinal hernia. Inguinal hernia accounts for 6% of surgical consultations. Males were the most represented, with a sex ratio of 13.3; the mean age was 50.39, with extremes ranging from 18 to 86 years. Farmers, shopkeepers and workers accounted for 46%. In 40.5% of cases, patients consulted for inguinal swelling. Preoperatively, the hernia was complicated in 13.5% (10) of patients. Hernial strangulation was the main preoperative complication in 13.5% (10). Treatment was essentially surgical; local anaesthesia was used in 75.7% of our patients, general anaesthesia in 5.4% and locoregional in 18.9%. The Shouldice technique was used in 99% of cases, the operative follow-up was simple in 44.6%, and the presence of keloids in 1.4%. Conclusion: The Shouldice technique was the technique of choice for inguinal hernia repair in community settings in developing countries because of its results and its affordability compared with other techniques using medical devices.
n Vitro Evaluation of Native Isolates of Lecanicillium spp (Berk & Broome) on Hemileia vastatrix
Authors: Romero Santos David , Arévalo Trinidad Castillo- , Zamora Markelyn José Rodríguez
Published: August 2023

With the objective of developing biological management options for coffee rust, through the characterization and evaluation of native isolates of Lecanicillium spp. The inoculum was obtained from hyperparasitized rust pustules and purified in potato dextrose agar culture medium. Lecanicillium spp. isolates were studied by microscopic, macroscopic, and physiological characterization, as well as In Vitro tests to determine the parasitism of each isolate on uredospores and rust pustules, and the potential for mass production of conidia on organic substrates: soybean, sorghum and rice. Six native isolates of the genus Lecanicillium spp. were obtained from 20 samples, with conidia ranging in size from 2.5 to 7.5 µ in length and from 1.5 to 2 µ in width, in groups or solitary, hyaline in color and cylindrical or ellipsoidal in shape. The size of the phialides ranged from 20 to 28 µ with a base width of 2.5 µ. Phialides were found solitary or in whorls originating from straight conidiophores, the conidia generally in groups of two to six, sometimes solitary. The average radial growth of Lecanicillium spp. 20 days after inoculation was 18 mm in PDA, 15 mm in EMA and 16 mm in SDA. The Majada isolate presented the highest percentage of viability with 99.7% at 22 hours. The isolate La Gotera on the soybean-based organic substrate showed the highest conidial yield of 1.08E+09 per gram of substrate compared to the other substrates and the other isolates. The Jinotega isolate presented the highest parasitism of uredospores in Petri dishes 16.6%. The highest percentage of parasitism on pustules was presented by the isolate La Gotera with 88.3%.
Conflict Resolution in Team: Analyzing the of Conflicts and Best Skills for Resolution
Authors: Adham Tawfig Khidir Ibnouf
Published: August 2023

This research study aimed to investigate and assess effective conflict resolution skills and interventions for managing conflicts within the team. Through a comprehensive literature review, a range of conflict resolution skills were identified and categorized into distinct domains. The first domain highlighted the significance of understanding cultural differences and emotional awareness in conflict resolution processes. The second domain emphasized the importance of fostering a cooperative and inclusive team atmosphere to facilitate conflict resolution. The third domain underscored the value of providing constructive feedback as an effective skill to address conflicts. In the fourth domain, effective communication and establishing positive relationships, were emphasized as crucial factors in resolving conflicts. The fifth domain recognized the significance of leadership skills in managing and mediating conflicts within the team. The sixth domain emphasized the skills of trust-building to encourage open dialogue and conflict resolution. The seventh domain highlighted the necessity for effective managerial strategies and decision-making processes in conflict resolution. Finally, the eighth domain encompassed various skills such as problem-solving skills, consistency and clarity skills, conflict analysis skills, active listening skills, and empathy skills, all of which were identified as essential in addressing conflicts within the team. The findings of this research study provide valuable insights into the diverse array of conflict resolution skills applicable to managing and resolving conflicts within the team.
Risk factors for death and illness severity in vaccinated versus unvaccinated COVID-2019 inpatients: a retrospective cohort study
Authors: Jorge Costa1 Guilherme , Roberto da Silva Junior2 José , Cesar Arruda da Silva2 Caio , Pessoa Ferreira de Lima3 Tiago , Menezes Costa2 Mariana , Henrique Oliveira Sousa2 Marcos , Carla dos Santos Costa1 Gabriela , Iran Costa Júnior1 José , Júlio Tabosa Sales2 Mozart
Published: August 2023

Objective: To determine the clinical profile of COVID-19 inpatients who were vaccinated prior to hospitalization and to compare the risk factors for death and the 28-day survival rate of between those inpatients vaccinated with one, two, or three doses and unvaccinated COVID-19 inpatients. Methods: This was a retrospective observational cohort study involving COVID-19 patients admitted to a referral hospital in the city of Recife, Brazil, between July of 2020 and June of 2022. Results: The sample comprised 1,921 inpatients, 996 of whom (50.8%) were vaccinated prior to hospitalization. After adjusting the mortality risk for vaccinated patients, those undergoing invasive mechanical ventilation (IMV) had the highest mortality risk (adjusted OR [aOR] = 7.4; 95% CI, 3.8-14.1; p < 0.001), followed by patients > 80 years of age (aOR = 7.3; 95% CI, 3.4-15.4; p < 0.001), and those needing vasopressors (aOR = 5.6; 95% CI, 2.9-10.9; p < 0.001). After adjusting the mortality risk for all patients, having received three vaccine doses (aOR = 0.06; 95% CI, 0.03-0.11; p < 0.001) was the most important protective factor against death. There were progressive benefits of vaccination, reducing the frequency of ICU admissions, use for IMV, and death (respectively, from 44.9%, 39.0% and 39.9% after the first dose to 16.7%, 6.2% and 4.4% after the third dose), as well as significant improvements in survival after each subsequent dose (p < 0.001). Conclusions: Vaccines were effective in reducing illness severity and death in this cohort of COVID-19 inpatients, and the administration of additional doses conferred them with accumulative vaccine protection.
Doxazosin, a Selective Alpha-1 Blocker, in the Treatment of Premature Ejaculation
Authors: Karabulut Musa , Günaydın Gürhan
Published: August 2023

Objective: Pharmacotherapy for premature ejaculation has been widely used for years. The efficacy of antidepressants, especially SSRIs, has been confirmed by many randomized controlled studies. The orthosympathetic activity on the ejaculatory system is a well-studied entity. In this study, our purpose is to evaluate the efficacy of a selective α-1 blocker, doxazosin, in the treatment of premature ejaculation.
Material and Methods: The study comprised 42 patients (mean age 39.11) out of a total of 44 patients with PE who were referred to Ege University Urology Outpatient Clinic from September 2000 to June 01. Among them, 27 patients were asked to use a daily dose of 4 mg of the α-blocker doxazosin for 6 weeks. The control group consisted of 15 patients who were asked to use 4 mg of placebo (starch) in the same way as doxazosin. After a therapy of 6 weeks, all the patients were interviewed to assess the efficacy of the therapy and to report any side effects.
Results: There was a significant increase in the latency of ejaculation with doxazosin in 12 out of a total of 27 patients (44.40%) compared to placebo, where only 2 out of 13 patients (13.30%) showed a similar effect. The effect of doxazosin was found to be statistically significant (p<0.043). The side effect profile showed no significant difference between doxazosin and placebo.
Conclusion: The result of our study indicates that doxazosin is safe and effective in patients with PE. Its activity is comparable to phenoxybenzamine and clomipramine, as reported in the literature. Additionally, its significantly lower and milder adverse effect profile appears to be an advantage.
Uji efektivitas ekstrak etanol daun senggani (Melastoma malabathricum L.) sebagai antihipertensi pada mencit putih jantan (Mus musculus)
Authors: Septiana Lilik , Tarigan Rida Evalina , Andry Muhammad , Irawan Vannissa Andriani , Nasution Muhammad Amin
Published: August 2023

Pendahuluan; daun senggani memiliki senyawa metabolit sekunder yang dapat menghambat pengeluaran aldosteron sehingga lebih banyak air dikeluarkan dari tubuh dan tekanan darah akan turun. Tujuan; untuk mengetahui efektivitas ekstrak etanol daun senggani (Melastoma malabathricum L.) terhadap penurunan tekanan darah mencit putih jantan (Mus musculus). Metode; eksperimental yang meliputi pengambilan sampel, pengolahan sampel, pembuatan ekstrak, karakteristik simplisia, penyiapan bahan uji, perlakuan terhadap hewan uji dan analisa data. Sampel yang digunakan yaitu daun senggani (Melastoma malabathircum L.) Hewan uji yang digunakan adalah 15 ekor mencit putih jantan kemudian dibagi menjadi 5 kelompok. Pengukuran tekanan darah menggunakan alat blood presure analyzer dengan etode tail cuff. Data hasil pengukuran kemudian dianalsis menggunakan uji paired t-test dengan batas kemaknaan 0,05. Hasil; ekstrak etanol daun senggani memiliki efektivitas antihipertensi dengan hasil pengukuran tekanan darah sistol paling rendah setelah perlakuan pada EEDS 150 mg/kgBB yaitu 86,66 mmHg dan diastol diperoleh tekanan darah paling rendah setelah perlakuan pada EEDS 150 mg/KgBB yaitu 59 mmHg. Hasil uji statistik paired t-test diperoleh adanya pengaruh pemberian bahan uji EEDS 50 mg/kgBB, EEDS 100 mg/kgBB, EEDS 150 mg/kgBB uji selama 14 hari dengan p-value < 0,05. Pada tekanan darah diastol pengaruh perlakuan pemberian bahan uji terhadap tekanan darah yang signifikan terdapat pada EEDS 150 mg/kgBB dengan p-value = 0,001. Kesimpulan; Pemberian ekstrak etanol daun senggani (Melastoma malabathricum L.) dapat menurunkan tekanan darah hewan coba mencit jantan (Mus musculus). Ekstrak etanol daun senggani (Melastoma malabathricum L.) efektif dalam menurunkan tekanan darah pada dosis 150 mg.
BLOOD PROFILE AND PHYSIOLOGICAL RESPONSE OF BROILER CHICKENS TO SWEET ORANGE PEEL SUPPLEMENTED WATER IN A HOT HUMID ENVIRONMENT
Authors: MAJEKODUNMI Bukola Christiana , LOGUNLEKO Mariam Opeyemi , ADEKUNLE Ezekiel Oluwafemi , ABIOJA Monsuru Oladimeji , ALABA Mojisola Opeyemi , ADELEKE Abiodun Jelili , JAMES Ikechukwu Joseph , DARAMOLA James Olamitibo
Published: August 2023

This study investigated the effect of sweet orange peel powder (SOPP) supplemented water on the rectal temperature (RT), respiratory rate (RR) and blood profile of broiler chickens raised in a hot humid environment. Day-old Ross broiler chickens (n = 96) were randomly allotted into four treatment groups: Control – without SOPP, 2 g SOPP, 4 g SOPP and 6 g SOPP per litre of water. Three replications of eight birds each per treatment in a completely randomized design were performed. Rectal temperatures were comparable (p > 0.05) among the treatments across the weeks except the third week. Birds on 6 g SOPP had a significantly (p < 0.05) higher value (41.32 °C) compared with birds in the control (40.90 °C) and 4 g SOPP (41.00 °C). Respiratory rate was not significantly different (p > 0.05) among treatments across the weeks. Significant (p < 0.05) variations were observed in the red blood cell (RBC) and mean corpuscular haemoglobin (MCH) values at week 4. However, at week 7, heterophil (H), lymphocyte (L), heterophil:lymphocyte ratio (H/L) and RBC were significantly (p < 0.05) different among the treatments. The H/L values were 0.42, 0.40, 0.38 and 0.36 for Control, 2 g SOPP, 4 g SOPP and 6 g SOPP, respectively. Serum biochemical indices examined were comparable among the treatment groups across the weeks. Inclusion of SOPP into drinking water of broiler birds did not adversely affect the birds as observed in the RT, RR and blood profile. Rather it helps the birds in coping with the environmental stress, as observed in the reduced H/L.
DIET SUPPLEMENTATION WITH YEAST BETA-GLUCANS, DIETARY ANTIOXIDANTS AND VITAMIN K IN BROILER CHICKENS MITIGATED AFLATOXIN-INDUCED GROWTH RETARDATION
Authors: ADEOGUN Jubril Bayonle , ABU Okhiomah Ahmed , EWUOLA Emmanuel Olubisi
Published: August 2023

Mitigation of inevitably absorbed aflatoxins following the addition of toxin binders are insufficiently reported. Therefore, effect of yeast beta-glucans, antioxidants such as vitamins C (VC) and E (VE), selenium (Se) and anti-haemorrhagic agent (vitamin K- VK) in the diet on changes in biochemical processes that characterised aflatoxins poisoning in broiler chickens was investigated. Aspergillus flavus 3228 inoculated maize was used to formulate a basal diet (BD) containing 270 ± 16µg.kg-1 total aflatoxins (AFB1 and AFB2). Unsexed one-day-old Arbor-Acres broiler chicks (n = 180) were randomly assigned into six dietary treatments, comprising Negative Control (NC- aflatoxin-free diet), BD and BD containing beta-glucans, VC, VE, VK and selenium. Two levels of beta-glucans: 250 and 375 mg.kg-1 (BD250 and BD375) and two combinations of vitamins with or without selenium: [(VE + VC) +VK] = ECK and [(VE + VC) + VK + Se] = ECKSe were combined to give BD250 + ECK; BD250 + ECKSe; BD375 + ECK and BD375 + ECKSe. Selenium, VC, VE and VK, were included in the diets at 0.3, 250, 200 and 3.0 mg.kg-1 of feed, respectively in augmented (2 x 2) +2 factorial arrangement in completely randomised design. The diets were fed to the chicken ad libitum for seven weeks. Serum malondialdehyde, reduced (GSH) and oxidised (GSSG) glutathione levels and ratio, body weight gain (BWG) were measured and feed conversion ratio (FCR) and percentage mortality were determined. Data were analysed using ANOVA at α0.05. Serum malondialdehyde and GSSG levels were significantly reduced (P < 0.05) from 159.41 ± 23.68 nM.mL-1 and 5.96 ± 5.20 µM.mL-1 in BD, to 69.68 ± 26.97 nM.mL-1 and 2.21 ± 0.88 µM.mL-1 in birds on BD375 + ECKSe. Birds fed BD375 + ECKSe had GSH:GSSG (3.58 ± 1.71), BWG (1,903.98 ± 32.56 g.bird-1) significantly higher and FCR (1.88 ± 0.04) was reduced (P < 0.05) compared to 1.06 ± 0.81; 956.27 ± 19.34 g.bird-1 and 2.38 ± 0.04, respectively, in birds on BD. Birds fed BD375 + ECKSe had no variation (P > 0.05) in performance when compared to NC. Mortality decreased significantly (P < 0.05) from 39.39 ± 5.25 % in BD to 9.09 ± 5.25 % in BD375 + ECK. Combinations of 375 mg.kg-1 beta-glucans, vitamins E, C, K and selenium reduced lipid peroxidation activity, feed conversion ratio and oxidative stress, with increased bodyweight gain. Finally, combinations of beta-glucans, antioxidants and vitamin K demonstrated effectiveness in preventing changes in biochemical processes leading to aflatoxins deleterious effects in broiler chickens.
THE TOXIC EFFECT OF HYPERGLYCAEMIA IN THE PATHOGENESIS OF SELECTED CHRONIC COMPLICATIONS OF DIABETES MELLITUS: A MINI-REVIEW
Authors: HRNKOVÁ Jana , DUPÁK Rudolf , CAPCAROVÁ Marcela
Published: August 2023

Diabetes mellitus is a group of metabolic diseases that, due to the long-term pathological effect of hyperglycaemia on tissues, lead to the development of typical chronic organ complications. Chronic hyperglycaemia leads to increased activity of the polyol pathway with subsequent accumulation of sorbitol and fructose, increased formation and accumulation of end products of advanced glycation, alteration of protein kinase C activity, excessive formation of reactive oxygen species and associated high level of oxidative stress. One of the most feared complications of diabetes mellitus is vision impairment and blindness. In this review, we address the most important metabolic pathways leading to the development of diabetic retinopathy and diabetic cataract, the ocular complications of diabetes with the greatest risk of vision loss.