bluuebunny/crossref_metadata_2025 huggingface dataset:
“Now is the time for institutions to be investing in growing exercise programs as part of standard of care”: a multiple case study examining the implementation of exercise oncology interventions
Authors: Czosnek Louise , Rankin Nicole M. , Cormie Prue , Murnane Andrew , Turner Jane , Richards Justin , Rosenbaum Simon , Zopf Eva M.
Published: June 2023

Background

Implementation science seeks to systematically identify determinants, strategies, and outcomes within a causal pathway to help explain successful implementation. This process is applied to evidence-based interventions (EBIs) to improve their adoption, implementation, and sustainment. However, this method has not been applied to exercise oncology services, meaning we lack knowledge about implementing exercise EBIs in routine practice. This study aimed to develop causal pathways from the determinants, strategies (including mechanism of change), and implementation outcomes to explain exercise EBIs implementation in routine cancer care.

Methods

A multiple-case study was conducted across three healthcare sites in Australia. Sites selected had implemented exercise within routine care for people diagnosed with cancer and sustained the delivery of services for at least 12 months. Four data sources informed the study: semi-structured interviews with staff, document reviews, observations, and the Program Sustainability Assessment Tool (survey). Framework analysis was applied to understand the findings. The Implementation Research Logic Model was used to identify commonalities in implementation across sites and develop causal pathways.

Results

Two hundred and eighteen data points informed our findings. Across sites, 18 determinants and 22 implementation strategies were consistent. Sixteen determinants and 24 implementation strategies differed across sites and results of implementation outcomes varied. We identified 11 common pathways that when combined, help explain implementation processes. The mechanisms of implementation strategies operating within the pathways included (1) knowledge, (2) skills, (3) secure resources, (4) optimism, and (5) simplified decision-making processes associated with exercise; (6) relationships (social and professional) and support for the workforce; (7) reinforcing positive outcomes; (8) capability to action plan through evaluations and (9) interactive learning; (10) aligned goals between the organisation and the EBI; and (11) consumer-responsiveness.

Conclusion

This study developed causal pathways that explain the how and why of successful implementation of exercise EBIs in cancer care. These findings can support future planning and optimisation activities by creating more opportunities for people with cancer to access evidence-based exercise oncology services.

Implications for cancer survivors

Understanding how to implement exercise within routine cancer care successfully is important so cancer survivors can experience the benefits of exercise.
Combining portable cone penetration test and electrical resistivity tomography to assess residual risks after shallow landslides: a case at the Hokkaido Eastern Iburi earthquake in 2018 in Japan
Authors: Yoshihara Naoyuki , Umezawa Ryosuke
Published: June 2023

Landscapes disturbed by shallow landslides present several residual risks. For example, residual soils on sliding surfaces may lead to the re-occurrence of shallow landslides, and landslide deposits on valley floors may introduce multiple hazards associated with river blocking or landslide damming. Despite such risks, few studies have investigated the residual risks following shallow landslides, and thus, no methodology has been established for assessing such risks. In this study, we combined portable cone penetration test (PCPT) and electrical resistivity tomography (ERT) to investigate the post-event risks associated with a landslide scar resulting from the 2018 Hokkaido Eastern Iburi earthquake (HEIE) in Japan. The multi-point PCPT identified the interface between a weak volcanic soil layer and underlying weathered sedimentary rocks. This interface exhibited an abrupt spatial change in resistivity, ranging from 20 to 100 Ωm. The thickness of the residual soil layer was 0.3–3.2 m and that of the landslide deposit exceeded 2.0 m. An infinite-slope stability analysis was performed to predict the re-occurrence of shallow landslides due to a lower intensity earthquake than that of HEIE in this region. Considering the area affected by the HEIE and the physical properties of soil layers, our findings imply a widespread risk of re-occurrence of shallow landslides over an area of 20 km × 20 km. Although the areal coverage of the combined ERT/PCPT method needs to be extended, it is effective for assessing the residual risks associated with shallow landslides.
Geometric and Inertial Properties of the Pig Head and Brain in an Anatomical Coordinate System
Authors: Soltan Nikoo , Siegmund Gunter P. , Cripton Peter A. , Jones Claire F.
Published: June 2023

Porcine models in injury biomechanics research often involve measuring head or brain kinematics. Translation of data from porcine models to other biomechanical models requires geometric and inertial properties of the pig head and brain, and a translationally relevant anatomical coordinate system (ACS). In this study, the head and brain mass, center of mass (CoM), and mass moments of inertia (MoI) were characterized, and an ACS was proposed for the pre-adolescent domestic pig. Density-calibrated computed tomography scans were obtained for the heads of eleven Large White × Landrace pigs (18–48 kg) and were segmented. An ACS with a porcine-equivalent Frankfort plane was defined using externally palpable landmarks (right/left frontal process of the zygomatic bone and zygomatic process of the frontal bone). The head and brain constituted 7.80 ± 0.79% and 0.33 ± 0.08% of the body mass, respectively. The head and brain CoMs were primarily ventral and caudal to the ACS origin, respectively. The mean head and brain principal MoI (in the ACS with origin at respective CoM) ranged from 61.7 to 109.7 kg cm2, and 0.2 to 0.6 kg cm2, respectively. These data may aid the comparison of head and brain kinematics/kinetics data and the translation between porcine and human injury models.
Randomized phase III trial of a neoadjuvant regimen of four cycles of adriamycin plus cyclophosphamide followed by four cycles of docetaxel (AC4-D4) versus a shorter treatment of three cycles of FEC followed by three cycles of docetaxel (FEC3-D3) in node-positive breast cancer (Neo-shorter; NCT02001506)
Authors: Hwang Inhwan , Kim Jeong Eun , Jeong Jae Ho , Ahn Jin-Hee , Jung Kyung Hae , Son Byung Ho , Kim Hak Hee , Shin Junyoung , Lee Hee Jin , Gong Gyungyub , Kim Sung-Bae
Published: June 2023

Purpose

To determine whether six cycles of FEC3-D3 has a comparable efficacy to eight of AC4-D4.

Methods

The enrolled patients (pts) were clinically diagnosed with stage II or III breast cancer. The primary endpoint was a pathologic complete response (pCR), and the secondary endpoints were 3 year disease-free survival (3Y DFS), toxicities, and health-related quality of life (HRQoL). We calculated that 252 pts were needed in each treatment group to enable the detection of non-inferiority (non-inferiority margin of 10%).

Results

In terms of ITT analysis, 248 pts were finally enrolled. The 218 pts who completed the surgery were included in the current analysis. The baseline characteristics of these subjects were well balanced between the two arms. By ITT analysis, pCR was achieved in 15/121 (12.4%) pts in the FEC3-D3 arm and 18/126 (14.3%) in the AC4-D4 arm. With a median follow up of 64.1 months, the 3Y DFS was comparable between the two arms (75.8% in FEC3-D3 vs. 75.6% in AC4-D4). The most common adverse event (AE) was Grade 3/4 neutropenia, which arose in 27/126 (21.4%) AC4-D4 arm pts vs 23/121 (19.0%) FEC3-D3 arm cases. The primary HRQoL domains were similar between the two groups (FACT-B scores at baseline, P = 0.35; at the midpoint of NACT, P = 0.20; at the completion of NACT, P = 0.44).

Conclusion

Six cycles of FEC3-D3 could be an alternative to eight of AC4-D4. Trial registration ClinicalTrials.gov NCT02001506. Registered December 5,2013.https://clinicaltrials.gov/ct2/show/NCT02001506
A Practice Pathway for the Treatment of Night Wakings in Children with Autism Spectrum Disorder
Authors: Galion Anjalee W. , Farmer Justin G. , Connolly Heidi V. , Allhusen Virginia D. , Bennett Amanda , Coury Daniel L. , Lam Janet , Neumeyer Ann M. , Sohl Kristin , Witmans Manisha , Malow Beth A. ,   Autism Treatment Network/Autism Intervention Research Network on Physical Health (ATN/AIR-P) Sleep Committee
Published: June 2023

Children with autism spectrum disorder (ASD) report high rates of sleep problems. In 2012, the Autism Treatment Network/ Autism Intervention Research Network on Physical Health (ATN/AIR-P) Sleep Committee developed a pathway to address these concerns. Since its publication, ATN/AIR-P clinicians and parents have identified night wakings as a refractory problem unaddressed by the pathway. We reviewed the existing literature and identified 76 scholarly articles that provided data on night waking in children with ASD. Based on the available literature, we propose an updated practice pathway to identify and treat night wakings in children with ASD.
On the origin of power-scaling exponents in silica aerogels
Authors: Aney Shivangi , Pandit Prakul , Ratke Lorenz , Milow Barbara , Rege Ameya
Published: June 2023

The macroscopic properties of open-porous cellular materials hinge upon the microscopic skeletal architecture and features of the material. Typically, bulk material properties, viz. the elastic modulus, strength of the material, thermal conductivity, and acoustic velocity, of such porous materials are expressed in terms of power-scaling laws against their density. In particular, the relation between the elastic modulus and the density has been intensively investigated. While the Gibson and Ashby model predicts an exponent of 2 for ideally connected foam-like open-cellular solids, the exponent is found to lie between 3 and 4 for silica aerogels. In this paper, we investigate the origins of this scaling exponent. Particularly, the effect of the pearl-necklace-like skeletal features of the pore walls and that of the random spatial arrangement is extensively computationally studied. It is shown that the latter is the driving factor in dictating the scaling exponent and the rest of the features play a negligible or no role in quantifying the scaling exponent.

Graphical Abstract
The role of GLUT2 in glucose metabolism in multiple organs and tissues
Authors: Sun Bo , Chen Hui , Xue Jisu , Li Peiwu , Fu Xu
Published: June 2023

The glucose transporter family has an important role in the initial stage of glucose metabolism; Glucose transporters 2 (GLUTs, encoded by the solute carrier family 2, SLC2A genes) is the major glucose transporter in β-cells of pancreatic islets and hepatocytes but is also expressed in the small intestine, kidneys, and central nervous system; GLUT2 has a relatively low affinity to glucose. Under physiological conditions, GLUT2 transports glucose into cells and allows the glucose concentration to reach balance on the bilateral sides of the cellular membrane; Variation of GLUT2 is associated with various endocrine and metabolic disorders; In this study, we discussed the role of GLUT2 in participating in glucose metabolism and regulation in multiple organs and tissues and its effects on maintaining glucose homeostasis.
Characteristic of Przewalski horses population from Askania-Nova reserve based on genetic markers
Authors: Musiał Adrianna D. , Ropka-Molik Katarzyna , Stefaniuk-Szmukier Monika , Myćka Grzegorz , Bieniek Agnieszka , Yasynetska Nataliya
Published: June 2023

Przewalski horses are considered the last living population of wild horses, however, they are secondarily feral offspring of herds domesticated ~ 5000 years ago by the Botai culture. After Przewalski horses were almost extinct at the beginning of the twentieth century, their population is about 2500 individuals worldwide, with one of the largest breeding centers in Askania-Nova Biosphere Reserve (Ukraine). The research aimed to establish the maternal variation of Przewalski horses population maintained in Askania-Nova Reserve based on mitochondrial DNA hypervariable 1 and hypervariable 2 regions profiling, as well as, analysis of Y chromosome single nucleotide polymorphism unique for Przewalski horses, and coat color markers: MC1R and TBX3. The mtDNA hypervariable regions analysis in 23 Przewalski horses allowed assigning them to three distinctly different haplotypes, showing the greatest similarity to the Equus caballus reference, the Equus przewalskii reference, and to extinct species—Haringtonhippus. The Y chromosome analysis using fluorescently labelled assays differentiated horses in terms of polymorphism (g731821T>C) characteristic of Equus przewalskii. All male individuals presented genotype C characteristics for Przewalski horses. The polymorphisms within the coat color genes indicated only native, wild genotypes. The Y chromosome and coat color analysis denied admixtures of the tested horses with other Equidae.
Evaluating Wagner Oxidation Criteria for Protective Al2O3 Scale Formation in Ni-Based Superalloys
Authors: Wo J. W. X. , Hardy M. C. , Stone H. J.
Published: June 2023

An assessment is made of the Wagner transition criteria for predicting the formation of a continuous Al2O3scale in Ni-based superalloys. Predictions are compared with data from an experimental Ni-based superalloy as well as commercial superalloys for which published data are available. The methodology was generally successful in predicting the transition temperature of the commercial superalloys but underpredicted the transition temperature of the experimental superalloy by approximately 50–100 °C. The difference in the transition temperature of the experimental superalloy to form a continuous Al2O3scale is primarily attributed to a complex oxide subscale that increased the internal volume fraction of oxide and led to reduced oxygen ingress. The sensitivity and limitations of the methodology are discussed, and recommendations are made to refine the methodology to facilitate the interpretation of oxidation behaviour in polycrystalline Ni-based superalloys.
Obesity phenotypes and cardiovascular risk: From pathophysiology to clinical management
Authors: Preda Alberto , Carbone Federico , Tirandi Amedeo , Montecucco Fabrizio , Liberale Luca
Published: June 2023

Obesity epidemic reached the dimensions of a real global health crisis with more than one billion people worldwide living with obesity. Multiple obesity-related mechanisms cause structural, functional, humoral, and hemodynamic alterations with cardiovascular (CV) deleterious effects. A correct assessment of the cardiovascular risk in people with obesity is critical for reducing mortality and preserving quality of life. The correct identification of the obesity status remains difficult as recent evidence suggest that different phenotypes of obesity exist, each one associated with different degrees of CV risk. Diagnosis of obesity cannot depend only on anthropometric parameters but should include a precise assessment of the metabolic status. Recently, the World Heart Federation and World Obesity Federation provided an action plan for management of obesity-related CV risk and mortality, stressing for the instauration of comprehensive structured programs encompassing multidisciplinary teams. In this review we aim at providing an updated summary regarding the different obesity phenotypes, their specific effects on CV risk and differences in clinical management.
Performance of new metal complexes for anionic and cationic dyes photodegradation: construction, spectroscopic studies, optical properties, and DFT calculations
Authors: Saleh Aml M. , Abd El–Wahab Zeinab , Ali Omyma A. M. , Faheim Abeer A. , Salman Aida A.
Published: June 2023

Water pollution is referred to as the introduction of exotic species into an ecosystem, which poses serious difficulties for both the environment and human health. As a result, water treatment has garnered a lot of interest in recent studies, particularly for dyes removal. In an effort to synthesize new photocatalysts with the highest potential for removing pollutants, photocatalytic degradation of two types of dyes; aniline blue, and malachite green by newly synthesized Ag(I), Ni(II), and Co(II) complexes photocatalysts has been investigated here. Ag(I), Ni(II), and Co(II) ions were used to interact with the novel imine ligand, HL, which was produced by condensing 3-acetylcoumarin, and sulfadimidine, in order to make the desired complexes. Different spectroscopic methods were used to properly characterize and confirm the structures of all synthesized compounds. The ligand, HL act as anionic tetradentate through the imine group (C=N), lactone carbonyl group (C=O), sulfonamide group (SO2NH), and pyrimidine ring nitrogen. The suggested formula of the synthesized complexes were [Ag2(L)(NO3)(H2O)3], [Co2(L)Cl3(H2O)].2H2O, and [Ni2(L)Cl3(H2O)].2H2O with a tetrahedral structure, and nonelectrolyte nature. Through optical studies and XRD measurements, all investigated compounds have the semiconductor nature and nano sizes. TGA-DTG/DSC techniques were utilized to thermal behavior study as well as assess some thermodynamic and kinetic parameters for all degradation stages. The geometry of the proposed structure of all new synthesized compounds was optimized by density functional theory (DFT) calculations. The BET surface area and the porosity data align well with the excellent photocatalytic performance for [Co2(L)Cl3(H2O)].2H2O complex toward the dyes degradation.
The added value of game elements: better training performance but comparable learning gains
Authors: Ninaus Manuel , Cortez Rodolpho , Hazin Izabel , Kiili Kristian , Wortha Silke M. , Klein Elise , Weiss Elisabeth M. , Moeller Korbinian
Published: June 2023

Even though game elements can increase motivation and engagement, they also might distract learners and thereby decrease performance and learning outcomes. In the current study, we investigated the effects of intrinsically integrated game elements on performance and learning outcomes. In a pre-post training study, 85 adult participants were randomly assigned either to the game-based or non-game-based training condition. Participants trained their fraction magnitude understanding with digital number line estimation tasks on five consecutive days (á 15–20 min). The learning outcomes were evaluated using a paper-based number line estimation task. While participants in both the game-based and non-game-based condition improved their fraction magnitude understanding from pretest to posttest, their improvement did not differ significantly. However, during the training, participants in the game-based condition responded more accurately but were slower than those in the non-game-based condition. The current results suggest that game elements might increase participants’ cognitive engagement and change their priorities or strategies (i.e., accuracy over speed) during learning. Nevertheless, better training performance did not lead to superior learning outcomes.
An Integrated Simulation of Multiple-Pass U-10Mo Alloy Hot Rolling and Static Recrystallization
Authors: Frazier William E. , Kalia Karun , Wang Chao , Choi Kyoo Sil , Field David P. , Hu Shenyang , Soulami Ayoub , Joshi Vineet V.
Published: June 2023

To achieve a desired microstructure and minimize the thickness variation in rolled foils, researchers must understand the effects of foil fabrication process variables on microstructure evolution. We developed an integrated simulation of deformation and recrystallization that employs the finite element method (FEM) and the kinetic Monte Carlo (KMC) Potts model, respectively, to investigate microstructure evolution during multiple-pass hot rolling and heat treatment in polycrystalline U-10Mo fuel. Scanning electron microscopy and electron backscatter diffraction images of microstructures were directly used as input in FEM calculation of deformation, and the calculated strains were used to determine the driving force of nucleation and growth of recrystallized grains in the Potts model. Grain structures predicted by the Potts model were used to update the grain structure and material properties for FEM. Simulation alternated between FEM and the Potts model to simulate grain structure evolution during multiple rolling and heat treatments. The initial model parameters were determined by benchmarking the recrystallization kinetics against experimental data. Then, the model was applied to predict the grain structure evolution. Results showed that our model can capture the coupling between deformation and recrystallization and can quantitatively reproduce the observed U-10Mo recrystallization and grain growth kinetics. The simulation results demonstrated that the developed model can predict U-10Mo grain structures as a function of initial microstructure and foil fabrication parameters.
‘This is what it is like to be church’: the Church of Sweden’s conditions for work with newly arrived refugees
Authors: Vikdahl Linda , Gunnarsson David , Larsson Sofia
Published: June 2023

Many newly arrived refugees suffer from mental health problems due to trauma. Research has shown that social participation after migration, such as taking part in social activities, networks and community work, is important for mental health and well-being. In Sweden, many civil society organisations, such as the Church of Sweden, take great responsibility for the establishment and integration of new arrivals. At the same time, the role of civil society organisations in the welfare society is not obvious, and the place of religious communities is sometimes challenged. Due to today’s growing secular and globalised society, the role of the Church of Sweden has changed. Its power has decreased, and the indications are that this will continue. There are also circumstances that point to the church having to adapt to the norms of secular society to have an impact. As the Church of Sweden fulfils an important function as a provider of welfare services, not least in work with newly arrived refugees, this article studies how the employees of the Church of Sweden feel about their conditions for this work and what guides it. It is based on a qualitative study of 19 interviews with employees in 4 different parishes.
Quality of life and satisfaction of patients after oncoplastic or traditional breast-conserving surgery using the BREAST-Q (BCT module): a prospective study
Authors: Ghilli M. , Mariniello M. D. , Ferrè F. , Morganti R. , Perre E. , Novaro R. , Colizzi L. , Camilleri V. , Baldetti G. , Rossetti E. , Coletti L. , Scatena C. , Ghilardi M. , Cossu M. C. , Roncella M.
Published: June 2023

Introduction

The oncoplastic conservative surgery was developed as a natural evolution of traditional surgery, attempting to improve the therapeutic and aesthetic outcomes where tumor resection could be followed by not-adequate results. Our primary aim is to evaluate how patient satisfaction and quality-of-life after conservative oncoplastic surgery, using BREAST-Q (BCT Module), change pre- and post-operatively. The secondary aim is to compare patient-reported outcome after oncoplastic or traditional conservative surgery.

Patients and methods

We enrolled 647 patients who underwent traditional conservative surgery or oncoplastic surgery from January 2020 to December 2022. Only 232 women (35.9%) completed the BREAST-Q questionnaire on a web-based platform, at the preoperative phase and 3 months after treatment.

Results

The average score of “Psychosocial well-being” and “Satisfaction with Breasts” 3 months after surgery showed a statistically significant improvement, while the average score for “Physical well-being: Chest” at 3 months showed a worsening compared to the baseline. “Sexual well-being” did not show statistically significant change. A significant difference between the post-operative outcome of oncoplastic surgery and traditional surgery was observed only for Physical well-being (better for traditional surgery).

Conclusions

The study showed significant improvement in patient-reported outcomes 3 months after the surgery, except for physical discomfort that increases especially after oncoplastic surgery. Furthermore, our data, as well as many others, point to the appropriateness of using OCS where there is an effective indication, while the perspective of patients cannot find significant superiority over TCS in any of the areas analyzed.
Operational research and business intelligence as drivers for digital transformation
Authors: Delias Pavlos , Kitsios Fotis C.
Published: June 2023

Digital transformation has become a crucial phenomenon, impacting society and industries through the implementation of digital technologies. It involves organizations adapting to gain a competitive edge, sense disruptions, and reorganize their business models. Challenges include the need for new strategies and skills, while opportunities arise from increased organizational performance and value creation through data utilization and innovative solutions. Overcoming inertia and resistance are critical in achieving successful digital transformation. Operational research plays a significant role in understanding and addressing these challenges and opportunities in the digital age. This article introduces the Special Issue on ‘Operational Research and Business Intelligence as Drivers for Digital Transformation’ and briefly discuss its relevance and the works it includes.
Effect of Fault Characteristics on Plastic Zones around Parallelly Spaced Two Underground Caverns and Shear Displacement along the Fault Plane
Authors: Prajapati Sandeep Kumar , Verma A. K.
Published: June 2023

One of the most significant challenges of construction of underground large size structures is to determine the effect of the geological discontinuities. Fault is a natural discontinuity which allows significant displacement of the rock mass along the fault plane and increases the plastic zones around the underground structure. For instance, an underground hydropower plant comprising more than two underground caverns and large distance between the underground cavern incurs the higher cost because of connecting tunnels or transfer of electricity from powerhouse cavern to transformer cavern. However, presence of the fault would result in the increase of the plastic zone and shear displacement along the fault. Thus, with regards to the effect of the fault on the stability of the two parallel caverns, in this paper different numerical models were simulated to study the effect of the fault on plastic zone around the cavern group and pillar between the caverns, and shear displacement along the fault plane under different scenarios such as fault location, fault dip angle, fault friction angle and in-situ stress conditions. The results are produced graphically and discussed. These results offer advance guidelines in construction of the two parallel large size caverns.
How Long a Tropical Mountainous Lake Can Survive? Inferences from Geochemistry and Radiometric Measurements of Pookode Lake, Kerala, India
Authors: Gopinath Girish , Resmi T.R. , Karunakara N. , Manjula P. , Jesiya N.P. , Sudeep Kumara K. , Srinivas Reji
Published: June 2023

Pookode, the freshwater lake in the Western Ghats, is a well-known tourist place in southern India, and human interference has turned the otherwise serene environment into a polluted one. This paper discusses the geochemical and textural characteristics of the Pookode lake and by determining the sedimentation rate, an attempt is made to predict the useful life of the lake. The predominance of mud fraction and high organic matter content in sediments favour the accumulation of heavy metals as indicated by the different indices. The sedimentation rate was determined using 137Cs dating method and the maximum lifespan of the lake maintaining its hydrological and ecological functions is estimated as ~700 years.
Analysis of Subsurface Soil Radon with the Environmental Parameters and Its Relation with Seismic Events
Authors: Hari Prasad Jaishi , Sanjay Singh , Raghavendra Prasad Tiwari , Ramesh Chandra Tiwari
Published: June 2023

This study reports continuous measurements of subsurface soil radon as well as environmental parameters for a period of three years. The survey was carried out along the active fault area in the Indo-Myanmar subduction zone in the north-eastern part which lies in the highest seismic zone of India. The wavelet-based decomposition of the environmental parameters was done using discrete wavelet transformation technique. The denoised environmental parameters by discrete wavelet transformation technique was fed as the inputs to the MLR (multiple linear regression) and MLP (multilayer perceptron) models. Residual radon was calculated and correlated with nearby seismic events. Many events of magnitude greater than or equal to 5 have occurred in the investigation area. It was possible to successfully correlate one event with the anomalous variation in soil radon. The correlated event was the only one with the shallow epicentral depth indicating that the investigated area has undergone a shallow rock fracturing due to the stress generated before the occurrence of the seismic event.
Simulation of nuclear magnetic resonance response based on 3D CT images of sandstone core
Authors: Jin Yuan , Xiao Liang , Li Wei , Wang Guanqun , Long Wei
Published: June 2023

In recent years, nuclear magnetic resonance (NMR) logging has become increasingly prevalent in the characterization of rock properties such as porosity, permeability, saturation, and pore size distribution. However, interpreting such properties accurately from NMR logging data is challenging for some reservoirs. In particular, the impact of salinity, viscosity, and saturation on NMR measurements is not always clear, which can lead to inaccuracies in the resulting data interpretation. Properly accounting for these factors is essential in order to obtain accurate and reliable measurements for effective characterization of subsurface formations. This study utilized a random walk technique to simulate the NMR response of homogeneous sandstones using 3D CT images and conducted a sensitivity analysis under various salinity, crude oil viscosity, and water saturation conditions. The results indicate that the T2 relaxation time slightly shifts toward the short relaxation direction as the salinity of the formation water increases. In addition, longer echo intervals result in a more significant forward shift in the T2 value than shorter intervals. Whereas, for crude oil, the T2 relaxation time becomes shorter as its viscosity increases. Furthermore, the effect of echo interval on the forward T2 shift is less pronounced for crude oil than it is for formation water. Under water wet conditions, the T2 spectrum of crude oil exhibits a peak at the volume relaxation position. As the water saturation decreases, the left two peaks in the T2 spectrum shift toward shorter relaxation times. Under oil wet conditions, the T2 spectrum exhibits a complex three-peak structure. The method provides a physical basis for interpreting NMR macroscopic responses, and the simulated NMR responses can help identify fluids in reservoirs.
The Virtual Couch: a Curriculum on the Question of the Fundamentals of Remote Psychotherapy—Pilot Study
Authors: Shekunov Julia , Swintak Cosima , Somers Kristin , Kolla Bhanuprakash , Ruble Anne , Bhatt-Mackin Seamus , Topor David , Murray Aimee , Romanowicz Magdalena
Published: June 2023

Objective

With a rise in remote clinical practice related to the COVID-19 pandemic, a novel remote psychotherapy curriculum was presented to psychiatry residents and fellows to address the urgent need to teach trainees how to adapt traditional psychotherapy skills to telepsychiatry settings.

Methods

Trainees completed a survey before and after receiving the curriculum to assess remote psychotherapy skills and areas for growth.

Results

Eighteen trainees (24% fellows, 77% residents) completed the pre-curriculum survey, and 28 trainees (26% fellows, 74% residents) completed the post-curriculum survey. Thirty-five percent of pre-curriculum participants indicated no experience with remote psychotherapy. Technology (24%) and patient engagement (29%) were identified as the greatest challenges in providing teletherapy pre-curriculum. Content related to patient care (69%) and technology (31%) was of most interest to pre-curriculum participants and identified as most helpful post-curriculum (53% and 26%, respectively). After receiving the curriculum, most trainees planned to make internal, provider-related changes to their remote teletherapy practice.

Conclusions

The remote psychotherapy curriculum was well received by psychiatry trainees who had limited experience with remote clinical practice prior to the pandemic.
Turbine Inlet Valve’s Self-Excited Vibrations Risk the Safe Operation of Hydropower Plants
Authors: Awad Hesham , Parrondo Jorge
Published: June 2023

Purpose

The main function of the turbine inlet valve (TIV) in a hydroelectric power plant is to prevent flow of water to the turbine whenever the turbine is not operating. Usually, the valve responsible for this operation is spherical with annular seals to perform the sealing function. Occasionally, when the valve is set into a closed orientation, the annular seal may not execute its sealing function properly though develop periodic oscillations accompanied by periodic leakage flows. These seal vibrations cause pressure fluctuations in the penstock pipeline, which risks the plant’s reliable and safe operation. Therefore, the primary goal of this research is to present a simplified theoretical model, able to clarify the excitation mechanism of the periodic seal vibration and simulate the plant’s transient behavior. Afterwards, develop some recommendations to enhance the stable operation of the (TIV).

Methods

The system governing equations comprises the water hammer equations to model the water flow through the various pipelines, the vibrating seal equation of motion, and the system boundary conditions.

Results

The dynamic instability of the (TIV) vibrations is more likely to arise at higher input reservoir energy levels and at the first harmonic of the seal oscillation. In addition, modifying the (TIV) by increasing pilot pipeline head losses and reducing its diameter can eliminate the (TIV) vibrations and warrant the plant’s safe operation.

Conclusion

Results revealed that fluid compressibility and acoustic transmission have a decisive effect on the fluid-dynamic forces acting on the seal and the (TIV) stability. In addition, the origin of the (TIV) vibrations is the valve leakage flow through the service seal.
Rescuing the Golgi from heat damages by ATG8: restoration rather than clean-up
Authors: Luo Anni , Liu Jian-Xiang
Published: June 2023

High temperature stress poses significant adverse effects on crop yield and quality. Yet the molecular mechanisms underlying heat stress tolerance in plants/crops, especially regarding the organellar remodeling and homeostasis, are largely unknown. In a recent study, Zhou et al. reported that autophagy-related 8 (ATG8), a famous regulator involved in autophagy, plays a new role in Golgi restoration upon heat stress. Golgi apparatus is vacuolated following short-term acute heat stress, and ATG8 is translocated to the dilated Golgi membrane and interacts with CLATHRIN LIGHT CHAIN 2 (CLC2) to facilitate Golgi restoration, which is dependent on the ATG conjugation system, but not of the upstream autophagic initiators. These exciting findings broaden the fundamental role of ATG8, and elucidate the organelle-level restoration mechanism of Golgi upon heat stress in plants.
Marine Ecosystem Bodies as Entangled Environments and Entangled Laws: Drones and the Marine Environment
Authors: Argüello Gabriela , Arvidsson Matilda , Krabbe Niels
Published: June 2023

The adoption of the 1982 UN Convention on the Law of the Sea (UNCLOS) and the steady development of international environmental law in the twentieth century shaped the marine environment as an object of legal protection. However, the exponential growth of substantive obligations to protect the marine environment, conserve marine biodiversity, and prevent marine pollution, has been largely ineffective due to lack of enforcement. Unmanned aerial vehicles (UAVs) deployed for marine environmental protection are seen, in scholarship and policy, as a means to close the enforcement gap, thereby revolutionizing the field by significantly increasing states’ maritime awareness. In contrast, our tentative analysis shows that while UAVs can translate complex environmental concerns into data readily available for analysis and action, such datafication of marine environments comes with high risks. More specifically, datafication enables multiple uses of gathered data, including for surveillance, military, and commercial purposes. These concerns tend to fall outside current debates on the international regulation of the use of UAVs in marine environments. In our essay, we explore whether international law recognizes the possibilities and risks involved in deploying UAVs into the marine environment. We draw on doctrinal and posthuman feminist legal approaches to analyze how UAVs interact with the wider context of “marine ecosystem bodies” in terms of international law, as well as how those terms may need to be reconfigured to accommodate the complexity of the many actors, agents, and materials of marine ecosystems.
The Non-Fungible Value of Local Associations and its Invisibility to Law
Authors: Cahill Maria
Published: June 2023

This article centers on the idea that there is a non-fungible value inherent in local associations. It uses the work of Paul Kahn to animate what that value might be and to consider why law might not have a clear sightline to it. In Democracy in Our America, Kahn, leaning on Tocqueville’s earlier work, reflects on the nature of volunteerism in local self-government and the value of local associations. Drawing on his experience-based account of the practice of local self-government, I suggest that local associations have a non-fungible value which comes in three dimensions: The dimension of care, the dimension of character, and the dimension of forum vibrancy. In The Cultural Study of Law, meanwhile, Kahn considers what the practice of the rule of law looks like and suggests that law is blind to other possible ways of framing and analyzing events. Building on this perspective, I reflect on how the practice of the rule of law ends up being blind to the value that is intrinsic to the local associations that vivify local communities. Through this lens, we can also understand more fully than has been possible to date why legal codifications of the principle of subsidiarity fail to result in a genuine preference for proximity.
The World of Constitutionalism is Not Flat
Authors: Bassok Or
Published: June 2023

In recent years, the emerging field of comparative constitutional law has been swept by a new approach with a scientific allure known as the Large-N approach. The methodology of this approach requires flattening the world of constitutional law by reducing the meaning of constitutional determinations into countable data. One of the difficulties in resisting this trend is that while many constitutional scholars have offered accounts that do not flatten the world of constitutional law, their methodology remains unarticulated and rarely discussed. Paul Kahn is one of the few scholars who offered an account of how to conduct non-doctrinal research of constitutional law. This Article aims to distil several principles of Kahn’s methodology, discuss its limitations, and demonstrate why it is superior to the Large-N approach. To achieve these goals, I chose to focus on three books on the German constitutional system that are based on dissertations written at Yale University, where Kahn teaches. Based on my discussion of these three books, I argue that Kahn’s methodology offers an approach which I dub the “Rich Picture” approach (or Rich-P). The Rich-P approach exposes that participants in a constitutional discourses understand constitutional materials, such as constitutional documents or judicial opinions, through a conceptual array that varies between legal orders. Without acknowledging the conceptual “eyeglasses” we wear when investigating constitutional determinations, measurements of the entire world of constitutionalism may lead to catchy soundbites and tweets, but to conclusions that are misleading at best.
The commutators of multilinear Calderón–Zygmund operators on weighted Hardy spaces
Authors: Han Yanyan , Wen Yongming , Wu Huoxiong , Xue Qingying
Published: June 2023

In this paper, we study the behaviours of the commutators $[\vec b,\,T]$ generated by multilinear Calderón–Zygmund operators $T$ with $\vec b=(b_1,\,\ldots,\,b_m)\in L_{\rm loc}(\mathbb {R}^n)$ on weighted Hardy spaces. We show that for some $p_i\in (0,\,1]$ with $1/p=1/p_1+\cdots +1/p_m$, $\omega \in A_\infty$ and $b_i\in \mathcal {BMO}_{\omega,p_i}$ ($1\le i\le m$), which are a class of non-trivial subspaces of ${\rm BMO}$, the commutators $[\vec b,\,T]$ are bounded from $H^{p_1}(\omega )\times \cdots \times H^{p_m}(\omega )$ to $L^p(\omega )$. Meanwhile, we also establish the corresponding results for a class of maximal truncated multilinear commutators $T_{\vec b}^*$.
A Late Holocene climate reconstruction from the high-altitude Lake Gölcük sedimentary records, Isparta (SW Anatolia)
Authors: Danladi Iliya Bauchi , Akçer-Ön Sena , Litt Thomas , Ön Z. Bora , Wacker Lukas
Published: June 2023

A high-resolution multiproxy lake sediment dataset, comprising lithology, radiography, μXRF elemental, magnetic susceptibility (MS), δ13C, and δ18O measurements since ca. AD 400 is presented in this study. Changes in lithology, radiography, magnetic susceptibility (MS), δ13C, and δ18O reflect wet/dry climate periods, whereas variability in log(Ca/K) can reflect warm/cold climate periods. Analyses of the multiproxy results allow the distinction of several climate periods, which may be associated with climatic phenomena such as changes in North Atlantic Oscillation (NAO) and/or solar activity. The influence of NAO−/NAO+ (negative/positive) is suggested to be related with the southward/northward displacement of the storm tracks resulting from the NAO−/NAO+ phases. For solar activity, the influence is explained through a direct increase in solar heating leading to calcite precipitation. The Dark Ages Cold Period (DACP, AD 450–750) reflects cold-dry climate conditions at this site, indicative of a positive North Atlantic Oscillation (NAO+) and low solar activity. The Medieval Climate Anomaly (MCA, AD 950–1250) exhibits wet-dry-wet and warm-cold-warm climate conditions. The wet/dry periods likely are associated with NAO−/NAO+, respectively, and the warm/cold period may reflect relatively high/low solar activity. The Little Ice Age (LIA, AD 1400–1850) is characterized by dry and cold climate conditions, suggesting the influence of NAO+ and low solar activity. Comparison of the results of this study with local and regional results suggests a generally similar climate pattern, which is indicative of similar climate mechanisms. The contradictions can be associated with age-related uncertainties, orographic differences, and/or other regional teleconnections.
Sisters Are Doing It for Themselves: How Female Combatants Help Generate Gender-Inclusive Peace Agreements in Civil Wars
Authors: THOMAS JAKANA L.
Published: June 2023

This article examines the effect rebel women have on the shape of civil war peace agreements, paying particular attention to the specific gender-inclusive provisions female rebels advocate for. I argue that, through conflict experiences and socialization, rebel women develop group identities that foster collective demands. Their identities as fighters and women from marginalized groups encourage rebel women to lobby for provisions that address the grievances of women from these societal groups. Using data on women’s participation in conflict and the terms written into contemporary peace agreements, I find support for this contention. Greater participation of female combatants is associated with an increased likelihood of observing gender-inclusive agreement provisions calling for the inclusion of women from marginalized groups and addressing the specific post-conflict needs of female ex-combatants. This study is one of the first to show that women’s participation in rebellion matters for the shape of post-conflict peace.
Sustainability analysis of the Mediterranean diet: results from the French NutriNet-Santé study
Authors: Baudry Julia , Neves Floriane , Lairon Denis , Allès Benjamin , Langevin Brigitte , Brunin Joséphine , Berthy Florine , Danquah Ina , Touvier Mathilde , Hercberg Serge , Amiot Marie-Josèphe , Pointereau Philippe , Kesse-Guyot Emmanuelle
Published: June 2023

The Mediterranean diet is often proposed as a sustainable diet model. This study aimed to evaluate the associations between adherence to the Mediterranean diet and sustainability domains in a cohort of French adults, using multiple criteria including nutritional quality, environmental pressures, monetary cost and dietary pesticide exposure. Food intakes of 29 210 NutriNet-Santé volunteers were assessed in 2014 using a semi-quantitative FFQ. Adherence to the Mediterranean diet was evaluated using the validated literature-based adherence score (MEDI-LITE). The associations between the MEDI-LITE and various sustainability indicators were examined using ANCOVA models, adjusted for sex, age and energy intake. Higher adherence to the MEDI-LITE was associated with higher nutritional quality scores, better overall nutrient profile as well as reduced environmental impact (land occupation: Q5 v. Q1: −35 %, greenhouse gas emissions: −40 % and cumulative energy demand: −17 %). In turn, monetary cost increased with increasing adherence to the Mediterranean diet (Q5 v. Q1: +15 %), while higher adherents to the Mediterranean diet had overall higher pesticide exposure due to their high plant-based food consumption. In this large cohort of French adults, greater adherence to the Mediterranean diet was associated with nutritional and environmental benefits, but also with higher monetary cost and greater exposure to pesticides, illustrating the necessity to develop large-scale strategies for healthy, safe (pesticide- and contaminant-free) and environmentally sustainable diets for all.
Clerical Child Sexual Abuse and the Culture Wars in France, 1891–1913
Authors: Verhoeven Timothy
Published: June 2023

This article investigates clerical child sexual abuse in the first decades of the French Third Republic. Thanks in large part to the difficulty of accessing relevant archival records, we know very little about this crime or how it was investigated by judicial officials. This study addresses this gap by drawing on a rich and untapped collection of correspondence between local prosecutors and the Ministry of Justice in Paris. The files reveal the process for investigating and prosecuting abusive priests, as well as the reverberations within local communities. Though generated by the state rather than the church, they offer an insight as well into the response of ecclesiastical authorities. Finally, they shed light on the relationship between clerical crime and the culture wars pitting French republicans against Catholics, a conflict that was reaching a peak of intensity in this period. What emerges from this study is an appreciation of the personal toll and political impact of clerical sexual abuse, as well as a new perspective on the recent scandals which have engulfed the Catholic church in a range of nations.