bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of the COVID-19 Pandemic on Those Supported in the Community with Long-Term Mental Health Problems: A Qualitative Analysis of Power, Threat, Meaning and Survival
Authors: Leeming Dawn , Lucock Mike , Shibazaki Kagari , Pilkington Nicki , Scott Becky
Published: January 2022

Research suggests that the COVID-19 pandemic has had a significant impact on those already living with mental health problems, though there is also evidence of resilience. However, to date there has been limited in-depth qualitative investigation. We interviewed 15 people living with long-term mental health problems who, before the pandemic, were being supported by third sector organisations, to explore how they experienced lockdowns and accessing services remotely. Template analysis was informed by the Power Threat Meaning Framework and suggested that participants experienced significant threats to their mental wellbeing and recovery which were exacerbated by current or previous powerlessness and inequality. Although participants described positive coping strategies, several described a return of unhelpful behaviours that had contributed to the original difficulties. The findings illustrate the wider contributions of social and economic context to mental health problems and the importance of ensuring that people do not feel abandoned and are proactively supported.
3D bioprinting of hydrogel/ceramic composites with hierarchical porosity
Authors: Condi Mainardi Jessica , Bonini Demarchi Catarina , Mirdrikvand Mojtaba , Karim Md Nurul , Dreher Wolfgang , Rezwan Kurosch , Maas Michael
Published: January 2022

Direct 3D bioprinting of bioreactors containing microorganisms embedded inside hydrogel structures is a promising strategy for biotechnological applications. Nevertheless, microporous hydrogel networks hinder the supply of nutrients and oxygen to the cell and limit cell migration and proliferation. To overcome this drawback, we developed a feedstock for 3D bioprinting structures with hierarchical porosity. The feedstock is based on a highly particle-filled alumina/alginate nanocomposite gel with immobilized E. coli bacteria with the protein ovalbumin acting as foaming agent. The foamed nanocomposite is shaped into a porous mesh structure by 3D printing. The pore radius diameters inside the non-printed, non-foamed nanocomposite structure are below 10 µm, between 10 and 500 µm in the albumin-stabilized foam and with additional pores in the range of 0.5 and 1 mm in the printed mesh structure. The influence of albumin on the bubbles and hence pore formation was analyzed by means of interfacial shear rheology and porosity measurements with X-ray microtomography (µCT). Furthermore, averaged diffusion coefficients of water in printed and non-printed samples with different albumin concentrations were recorded using nuclear magnetic resonance (NMR) tomography to assess the water content in the porous structure. Moreover, the effective viability and accessibility of embedded E. coli cells were analyzed for various material compositions. Here, the addition of albumin induced bacterial growth and the porosity increased the effective viability of the embedded bacteria, most likely because of enhanced accessibility of the cells. The experimental results demonstrate the potential of this approach for producing macroscopic bioactive materials with complex 3D geometries as a platform for novel applications in bioprocessing.
Risk factors for clinically relevant deviations in patients’ medication lists reported by patients in personal health records: a prospective cohort study in a hospital setting
Authors: van der Nat Denise J. , Taks Margot , Huiskes Victor J. B. , van den Bemt Bart J. F. , van Onzenoort Hein A. W.
Published: January 2022

Background Personal health records have the potential to identify medication discrepancies. Although they facilitate patient empowerment and broad implementation of medication reconciliation, more medication discrepancies are identified through medication reconciliation performed by healthcare professionals. Aim We aimed to identify the factors associated with the occurrence of a clinically relevant deviation in a patient’s medication list based on a personal health record (used by patients) compared to medication reconciliation performed by a healthcare professional. Method Three- to 14 days prior to a planned admission to the Cardiology-, Internal Medicine- or Neurology Departments, at Amphia Hospital, Breda, the Netherlands, patients were invited to update their medication file in their personal health records. At admission, medication reconciliation was performed by a pharmacy technician. Deviations were determined as differences between these medication lists. Associations between patient-, setting-, and medication-related factors, and the occurrence of a clinically relevant deviation (National Coordinating Council for Medication Error Reporting and Prevention class $$\ge$$
≥
E) were analysed. Results Of the 488 patients approached, 155 patients were included. Twenty-four clinically relevant deviations were observed. Younger patients (adjusted odds ratio (aOR) 0.94; 95%CI:0.91–0.98), patients who used individual multi-dose packaging (aOR 14.87; 95%CI:2.02–110), and patients who used $$\ge$$
≥
8 different medications, were at highest risk for the occurrence of a clinically relevant deviation (sensitivity 0.71; specificity 0.62; area under the curve 0.64 95%CI:0.52–0.76). Conclusion Medication reconciliation is the preferred method to identify medication discrepancies for patients with individual multi-dose packaging, and patients who used eight or more different medications.
Is Leave for Fathers Pronatalist? A Mixed-Methods Study of the Impact of Fathers’ Uptake of Parental Leave on Couples’ Childbearing Intentions in South Korea
Authors: Lee Youngcho
Published: January 2022

While many countries with low birth rates have implemented policies incentivizing fathers to take parental leave with the anticipation that it will contribute to raising birth rates, there is scant research empirically testing whether fathers’ uptake of leave is pronatalist. Existing research is limited to a few European (mostly Nordic) countries, and it is unclear whether there exists a positive causal relationship. Using mixed methods, this paper seeks to explore the processes and mechanisms by which fathers’ uptake of parental leave impacts intentions for additional children in South Korea, a country characterized by lowest-low fertility and low but rapidly expanding uptake of leave by fathers. Results based on multinomial logistic regression models suggest that in comparison to fathers who expect to take their first leave shortly, fathers with leave experience are less likely to report couple-level intentions for another child, significantly so at parity two. Interviews of fathers with parental leave experience confirm that fathers attenuate their fertility intentions downwards in light of the difficulties of childcare during their leave. While these intentions may change further down the line and/or couples may decide to continue an unplanned pregnancy, results suggest that fathers’ parental leave has an anti- rather than pronatalist effect in South Korea. This study demonstrates that in countries with poor support for the reconciliation of employment and childcare, equalizing the gendered division of parental leave may not be sufficient to see a reversal in its fertility trends.
Tissue Distribution, Histopathological and Genotoxic Effects of Magnetite Nanoparticles on Ehrlich Solid Carcinoma
Authors: Bassiony Heba , El-Ghor Akmal A. , Salaheldin Taher A. , Sabet Salwa , Mohamed Mona M.
Published: January 2022

Nanoparticles can potentially cause adverse effects on cellular and molecular level. The present study aimed to investigate the histopathological changes and DNA damage effects of magnetite nanoparticles (MNPs) on female albino mice model with Ehrlich solid carcinoma (ESC). Magnetite nanoparticles coated with L-ascorbic acid (size ~ 25.0 nm) were synthesized and characterized. Mice were treated with MNPs day by day, intraperitoneally (IP), intramuscularly (IM), or intratumorally (IT). Autopsy samples were taken from the solid tumor, thigh muscle, liver, kidney, lung, spleen, and brain for assessment of iron content, histopathological examination, and genotoxicity using comet assay. The liver, spleen, lung, and heart had significantly higher iron content in groups treated IP. On the other hand, tumor, muscles, and the liver had significantly higher iron content in groups treated IT. MNPs induced a significant DNA damage in IT treated ESC. While a significant DNA damage was detected in the liver of the IP treated group, but no significant DNA damage could be detected in the brain. Histopathological findings in ESC revealed a marked tumor necrosis, 50% in group injected IT but 40% in group injected IP and 20% only in untreated tumors. Other findings include inflammatory cell infiltration, dilatation, and congestion of blood vessels of different organs of treated groups in addition to appearance of metastatic cancer cells in the liver of non-treated tumor group. MNPs could have an antitumor effect but it is recommended to be injected intratumorally to be directed to the tumor tissues and reduce its adverse effects on healthy tissues.
Stuck in a Time Warp? The Great Recession and the Socio-occupational Integration of Migrants in Spain
Authors: Jiménez-García Juan Ramón , Levatino Antonina
Published: January 2022

This article examines the socio-occupational integration of the immigrant population in Spain for a time span that, for the first time, includes the post-crisis period. Using the Spanish Labour Force Survey and conducting a socio-occupational analysis, we predict the probability that a migrant would be employed in one socio-occupational class over another in three periods: before, during and after the crisis. Our main research questions are as follows: (1) To what extent do migrants tend to be located in certain socio-occupational classes? (2) To what extent does the likelihood of belonging to a certain socio-occupational class differ according to immigrants’ places of origin? (3) Can differences be found in the likelihood of belonging to a certain socio-occupational class according to the places of origin before, during and after the Great Recession? The results show a very unequal distribution of immigrants in the socio-occupational structure according to their origin. While immigrants from Schengen Europe and North America are better located in the occupational structure, those from Eastern Europe and Africa are over-represented in the lower socio-occupational classes.
UNsupported: The Needs and Rights of Children Fathered by UN Peacekeepers in the Democratic Republic of Congo
Authors: Wagner Kirstin , Bartels Susan A. , Weber Sanne , Lee Sabine
Published: January 2022

Sexual exploitation and abuse (SEA) by United Nations (UN) peacekeepers causes severe physical and psychological consequences. Where SEA leads to pregnancy and childbirth, peacekeepers typically absolve themselves of their paternal responsibilities and paternity suits are largely unsuccessful. The lack of support for peacekeeper-fathered children (PKFC) tarnishes the image of the UN who fails to implement a victim-centred approach to SEA. Analysing shortcomings in the provision of support, this article presents an evaluation of the UN’s accountability system from the perspective of PKFC families. In-depth interviews with thirty-five PKFC and sixty mothers demonstrate local barriers to child support and paternity claims in eastern Democratic Republic of Congo. We discuss PKFC’s need for assistance and their mothers’ attempts to navigate an opaque international legal system. The findings cast light on their limited access to UN subsidies and offer recommendations to better implement existing UN goals of justice and victim-oriented policies.
Bhaaratha Craton - The Monolithic Precambrian Terrain of the Indian Peninsula
Authors: Subrahmanya K. R.
Published: January 2022

Dharwar Craton and the Southern Granulite Terrain have always been a topic of interest. The opinion prevailing earlier was that the Southern Peninsula has undergone progressive metamorphism from north to south as exemplified by the green schist facies, amphibolite facies (intracratonic Proterozoic sediments and Dharwars) and finally the granulite facies south of the Fermor Line. Currently, the nature of contact between the granulite terrain and the Dharwars is being debated. Rocks equivalent of Sargurs and Dharwars are found in Tamil Nadu and also below the Deccan Basalts, indicating that the Dharwars extend both to the north and south. Likewise, views vary on the movement of Nilgiris. Nilgiris, Anaimalai and the adjacent mountain ranges to the east are all due to down throw of the Kaveri Crater region followed by easterly tilt of the Western Ghats at the time of separation of India and Madagascar. Dharwars have been subdivided into Western, Eastern and Central. However, there are no unambiguous evidences to justify such divisions. Various cratonic blocks of the Indian peninsula are separated by rift valleys and faults, thus indicating the possibility of all the blocks being one unit earlier. The earliest supercontinent Ur had triangular Indian Peninsula as the nucleus bordered by Kaapval and Pilbara. Similar shape of India continues in all the subsequent Supercontinent reconstructions. Peninsula as a whole shows a northerly tilt except in places which have evidences of intraplate deformation.
Crustal Melting Evidence in Migmatites of Higher Himalayan Crystallines (HHC) along Bhagirathi, Dhauliganga Valleys, and Sikkim Himalaya, India
Authors: Singh Sandeep , Rit Bitihotri , Mohan Shashank Prabha , Kushwaha Aman
Published: January 2022

An attempt has been made to evaluate crustal melting evidence through textural studies within a narrow zone of migmatite present in NW Himalaya along Bhagirathi and Dhauliganga valleys and two zones close to MCT and throughout within in the Sikkim Himalayas, NE Himalaya. It appears that partial melting was initiated by muscovite dehydration melting with a positive volume change driving melt segregation and discontinuous crystallization of peritectic biotite in the leucosome. Further, during retrogression due to cooling, a certain amount of melt was consumed. The occurrence of isolated pseudomorphosed melt pockets and lack of euhedral magmatic flow textured feldspar further indicates that the melt fraction was low for the alignment of crystals. The processes of melt segregation and migration could have been limited. The migmatite leucosomes and a small volume of in situ tourmaline-bearing leucogranite along extensional crenulation cleavages and melt pods indicate water-saturated melting of pelitic metasedimentary rocks. The formation of migmatites happened at around 46 Ma, corresponding to a peak metamorphic event due to collisional tectonics of the Himalayan orogeny. The presence of feeder dikes for main tourmaline-bearing leucogranite indicates that the source for the main body could be migmatite which is also supported by the similarity in REE patterns of the main body and in situ tourmaline-bearing leucogranite.
Study of Micro-structures and their Relation with Occurrence of Mineral Matter in Ramagundam Coals, Godavari Basin, India: Implications on Coal and Hydrocarbon Industries
Authors: Rai Shweta , Rai Ankita , Kumar Kajal , Naik Amiya S. , Singh Neelratan , Srivastava D.K. , Singh Prakash K.
Published: January 2022

This paper is an attempt to study the relationship between coal microstructures and mineral matter in Ramagundam Gondwana coal of Godavari basin. For this purpose, the occurrence and distribution of mineral matter in different lithotypes and microlithotypes have been investigated and their association with organic matter has been studied. The work has been accomplished through detailed petrography, SEM-EDS and XRD studies. Presence of clay minerals and pyrite, along with trace amounts of apatite, ankerite, hematite, calcite, dolomite and quartz has been revealed from the study. The lithotypes and bands have variable concentrations of mineral matter which occurs associated with different microstructures in coal. Optical microscopy reveals that mineral matter occurs maximum in dull-coal but it is almost equally distributed in dull-banded coal and banded-bright coal. The study also incorporates the nature of fracture and phyteral pores and their association with mineral matter. Vitrain is characterized by cleats, micropores and microfractures which are often filled up partially or completely with mineral matter; fusain has well preserved tracheids with open pits and partially homogenized cell structure filled with mineral matter. In durain and clarain lithotypes, the minerals are intimately intergrown with the organic constituents.
AHP and GIS-based Delineation of Groundwater Potential of Papum Pare District of Arunachal Pradesh, India
Authors: Mahato Ranjit , Bushi Dhoni , Nimasow Gibji , Nimasow Oyi Dai , Joshi Ramesh Chandra
Published: January 2022

Water is crucial to human survival. Studies on surface water are well documented but precise knowledge of groundwater resources is difficult. Thus, accurate knowledge of groundwater resources could meet the necessities of water at present and in the long run. Application of the Analytic Hierarchy Process (AHP) and Geographical Information System (GIS) together with multicriteria parameters has emerged as an efficient technique for delineation of groundwater potential in recent decades. However, no efforts to delineate the groundwater potential have been attempted in the study area till date. Hence, in this study, the groundwater potential of Papum Pare district of Arunachal Pradesh was delineated by combining AHP, overlay analysis, GIS, and ten thematic layers (geomorphology, geology, slope, lineament density, drainage density, rainfall, distance from the major river, topographic wetness index, soil texture, and land use/land cover). The results show about 64% of the area under poor groundwater potential. Moderate and good groundwater potential is found in 31% and 5% of the area. Map-removal and single-parameter sensitivity analyses revealed that the groundwater potential map is most sensitive to the annual average rainfall with a mean variation index of 1.05% and a weight of 19.07%. The flood/alluvial plains, Siwalik formations with sediments, and level to gentle slopes receiving high rainfall show good potential, and the dissected hills/ valleys, metamorphic rock assemblages, steep slopes with low rainfall reveals poor groundwater potential. The overall accuracy of 81.25% with a Kappa coefficient of 0.72 explains good agreement between the reference data and the map. The estimated area under good groundwater potential appears too little concerning the increasing population and urbanization. Therefore, the state government in general and the water resources and planning department in particular need to formulate suitable strategies to combat the water scarcity scenario waiting ahead. The study suggests raising the use of surface water from nearby rivers to lessen the pressure on groundwater resources.
Characterization of Ordovician-Silurian Acritarchs from the Kumaon Tethys Himalaya, Pithoragarh District, Uttarakhand, India
Authors: Sinha Hareshwar N.
Published: January 2022

Acritarchs, microphytoplankton of algal protists, from the Shiala and Yong Limestone formations of the Gunji village along Kali river (upstream) of Kumaon Tethyan Himalaya, Pithoragarh district, Uttrakhand, India have been examined for the first time. It aims to test the basin-wide existence and testing the reliability of already locally established biozones from the Garhwal Tethys Himalaya, Chamoli district, Uttrakhand. The study reveals moderate to poorly preserved, matured assemblages and diversified forms of acritarchs from both formations. The assemblage includes sphaeromorphs, acanthomorphs, netromorphs, polygonomorphs, diacromorphs, herkomorphs, etc. Two palynoassemblages have been recognized each from the Shiala and Yong Limestone formations. Palynoassemblage (I) from the Shiala Formation is confirmed by one productive sample which reveals a mix of Late Ordovician and Silurian forms. The acritarchs assemblage assigned to 16 genera with at least 13 species. The acritarchs from the Yong Limestone Formation are more plentiful and diverse confirming the Palynoassemblage (II) that contains biostratigraphically significant forms of typical Silurian (Ludlow) age. This Palynoassemblage is assigned to 23 genera with 16 species. The paper also describes the possible reasons for floral difference from the same formation and basin sampled at two different localities of the Tethys Himalaya, possibly due to palaeoclimatic constraints. However, detailed work on this aspect is required.

The palynoassemblages from both the formations describe morphologically non-distinct, ubiquitous, wide palaeogeographic spread and uncertain stratigraphic taxa too along with biostratigraphic significant forms.
Morphometric Analysis of Baner, Neogal and Awa River Basins, Himachal Pradesh, India
Authors: Sharma Ravi , Rajwant  , Singh Yudhbir , Singh Neelratan , Sangra Rameshwar
Published: January 2022

The present study aims at evaluating the morphometric parameters of Baner, Neogal and Awa river basins in Himachal Pradesh, India for making important assessments about the morphometric characteristics and geo-hydrological conditions of these watersheds. Georeferenced Survey of India toposheets, Cartosat-DEM are the datasets used in ArcGIS software for the delineation of watersheds and calculating important morphometric parameters along with the preparation of relief, slope, aspect and drainage basin asymmetry maps. The results show that the Neogal and Awa rivers are of 6th order whereas Baner river is of 7th order. The basins are of elongated shape and the drainage is mainly of sub-dendritic to dendritic type. In the northern regions of these river basins, the slopes are very steep and the relief is very high that results in rapid runoff and increases the intensity of erosion. High drainage density (>2.8) and fine drainage texture (>9) indicate moderately permeable subsurface material that causes groundwater deficit. These watersheds have developed asymmetrical drainage and their high ruggedness values (>12) refers to the rejuvenated stage of their geomorphic development. The study concludes that erosion-prone areas with rapid runoff are present in the area and adequate measures will assist in the sustainable management of land and water resources.
Release of Fluoride in Groundwater from Various Rock Forming Minerals and Sandy Aquifer of Central Ganga Basin, India
Authors: Singh Pragya , Saxena Abhishek
Published: January 2022

Fresh and pure water has an important role to play for healthy life. Currently, in many studies higher concentrations of contaminants like calcium, sodium, nitrate, lead, chromium, arsenic, fluoride etc. have been reported that makes the water unfit for its direct consumption. Sources and release mechanism of many such pollutants is still not known. These sources can be anthropogenic or geogenic. This paper deals with one of such contaminants namely fluoride and emphasizes on its release from various minerals viz. Gypsum, fluorite, tourmaline, actinolite, plagioclase, biotite, quartz, kayanite, epidote and orthoclase under different pH environment. It has been noted that maximum fluoride has been released from the fluorite at all pH environment (acidic, normal and alkaline) of water while minimal fluoride was released from kayanite. However, orthoclase, tourmaline and biotite can release fluoride in considerable amount. The attempts were also made to compare the release of fluoride from modern sand (Ganga sediments) with ancient sand (from sandy aquifer) under different pH condition. Outcome of studies shows that maximum fluoride released from the sand at the pH range of 6.1 to 8.2.
Metrics and Algorithms for Locally Fair and Accurate Classifications using Ensembles
Authors: Lässig Nico , Oppold Sarah , Herschel Melanie
Published: January 2022

To obtain accurate predictions of classifiers, model ensembles comprising multiple trained machine learning models are nowadays used. In particular, dynamic model ensembles pick the most accurate model for each query object, by applying the model that performed best on similar data. Dynamic model ensembles may however suffer, similarly to single machine learning models, from bias, which can eventually lead to unfair treatment of certain groups of a general population. To mitigate unfair classification, recent work has thus proposed fair model ensembles, that instead of focusing (solely) on accuracy also optimize global fairness. While such global fairness globally minimizes bias, imbalances may persist in different regions of the data, e.g., caused by some local bias maxima leading to local unfairness.

Therefore, we extend our previous work by including a framework that bridges the gap between dynamic model ensembles and fair model ensembles. More precisely, we investigate the problem of devising locally fair and accurate dynamic model ensembles, which ultimately optimize for equal opportunity of similar subjects. We propose a general framework to perform this task and present several algorithms implementing the framework components. In this paper we also present a runtime-efficient framework adaptation that keeps the quality of the results on a similar level. Furthermore, new fairness metrics are presented as well as detailed informations about necessary data preparations.

Our evaluation of the framework implementations and metrics shows that our approach outperforms the state-of-the art for different types and degrees of bias present in training data in terms of both local and global fairness, while reaching comparable accuracy.
UEFA’S financial fair play regulations: a good example of best practice governance by a sporting body?
Authors: Dunbar Neil , Middleton Thomas
Published: January 2022

The Union of European Football Associations (UEFA) is the body that governs European football. In 2010 it introduced its Financial Fair Play (FFP) Regulations with the main aim of bringing financial stability to European football. This article examines UEFA’s FFP Regulations from good governance and ‘best practice’ perspectives. It finds that the setting-up, implementation and monitoring of the FFP Regulations by UEFA generally adhere to ‘best practice’ principles. However, recent cases in the Court of Arbitration for Sport have revealed several areas where changes to the regulations would be appropriate. In 2021 UEFA made some changes to its Procedural rules governing its Club Financial Control Body, which address some of the outstanding issues but there are still a number of areas where changes would be beneficial as these would provide greater clarity and transparency to its operation and enforcement and thereby promote more timely and cost-effective regulation.
Ultrasound shear wave elastography imaging of common carotid arteries in patients with Spontaneous Coronary Artery Dissection (SCAD)
Authors: Al-mutairi Fahad F. , Al-hussaini Abtehal , Marsh Anne-Marie , Samani Nilesh , McCann Gerry , Adlam David , Chung Emma M. L. , Ramnarine Kumar V.
Published: January 2022

Background

Shear wave elastography (SWE) is emerging as a valuable clinical tool for a variety of conditions. The aim of this pilot study was to assess the potential of SWE imaging of the common carotid arteries (CCA) in patients with spontaneous coronary artery dissection (SCAD), a rare but potentially life-threatening condition, hypothesized to be linked to changes in vessel wall elasticity.

Methods

Ultrasound shear wave elastography (SWE) estimates of artery wall elasticity were obtained from the left and right CCAs of 89 confirmed SCAD patients and 38 non-dissection controls. SWE images obtained over multiple cardiac cycles were analysed by a blinded observer to estimate elasticity in the form of a Young’s Modulus (YM) value, across regions of interest (ROI) located within the anterior and posterior CCA walls.

Results

YM estimates ranged from 17 to 133 kPa in SCAD patients compared to 34 to 87 kPa in non-dissection controls. The mean YM of 55 [standard deviation (SD): 21] kPa in SCAD patients was not significantly different to the mean of 57 [SD: 12] kPa in controls, p = 0.32. The difference between groups was 2 kPa [95% Confidence Interval − 11, 4].

Conclusions

SWE imaging of CCAs in SCAD patients is feasible although the clinical benefit is limited by relatively high variability of YM values which may have contributed to our finding of no significant difference between SCAD patients and non-dissection controls.
Four New Horsemen of an Apocalypse? Solar Flares, Super-volcanoes, Pandemics, and Artificial Intelligence
Authors: Noy Ilan , Uher Tomáš
Published: January 2022

If economists have largely failed to predict or prevent the Global Financial Crisis in 2008, and the more disastrous economic collapse associated with the pandemic of 2020, what else is the profession missing? This is the question that motivates this survey. Specifically, we want to highlight four catastrophic risks – i.e., risks that can potentially result in global catastrophes of a much larger magnitude than either of the 2008 or 2020 events. The four risks we examine here are: Space weather and solar flares, super-volcanic eruptions, high-mortality pandemics, and misaligned artificial intelligence. All four have a non-trivial probability of occurring and all four can lead to a catastrophe, possibly not very different from human extinction. Inevitably, and fortunately, these catastrophic events have not yet occurred, so the literature investigating them is by necessity more speculative and less grounded in empirical observations. Nevertheless, that does not make these risks any less real. This survey is motivated by the belief that economists can and should be thinking about these risks more systematically, so that we can devise the appropriate ways to prevent them or ameliorate their potential impacts.
Orchard management strategies to reduce bruises on apples in India: a review
Authors: Golombek Sabine D. , Blanke Michael M.
Published: January 2022

India is the fifth-largest apple producer in the world with more than 2 MT per year. Mechanical damage such as bruises of apples (Malus domestica Borkh.), which can result in considerable wastage and decline in quality, is a major problem of the apple industry. On-site investigations of apple orchard management strategies to reduce bruises in Northern India were conducted by the first author in collaboration with the University of Bonn. The apple industry including the farmers is in a continuous process of reducing losses caused by mechanical damage. Apple bruises can develop along the whole value chain. Orchard management offers countermeasures to reduce bruise susceptibility of the apples. At harvest, bruises can be caused by impact and compression forces due to unsuitable practices. This review explains the formation and development of bruises, followed by the causes of mechanical damage and orchard management measures to reduce or avoid bruises, with particular regard to India. The orchard management measures include crop load management, fruit water status and nutrient composition, maturity stage, harvest time later in the day, gentle harvest methods, packing into soft, padded bins and careful transport of the apple bins out of the orchard.
Abandoning Gender “Identity”
Authors: Gilleri Giovanna
Published: January 2022

International instruments fail to specify the meaning of gender identity. Yet gender identity has been invoked as a prohibited ground of discrimination, particularly in cases concerning trans persons. Trans existences fall outside the expectation of a correspondence between sex and gender. “Trans” is an umbrella term referring to people who do not identify with the sex attributed to them at birth. This broad definition encompasses pre-operative and post-operative transsexuals, as well as persons who have not undergone any medical intervention and do not conform to the social norms of expression and self-identification imposing the binary. Regional conventions do not define the concept of gender identity either. Documents issued by the United Nations (UN) and regional human rights bodies frequently rely on the category, without any clear explanation of the notion, or of what makes gender identity different from gender as such. Relying on Lacanian psychoanalysis, this essay argues that gender is an identity per se and challenges international law's treatment of gender and gender identity as distinct categories. Underlying this essay is the view that questioning the shape that the law gives to “gender identity” is the preliminary step to evaluating what protections human rights law can or cannot offer to individuals.
Doing Queer in the Everyday of Academia: Reflections on Queering a Conference in International Law
Authors: Schramm Bérénice K. , Santos de Carvalho Juliana , Holzer Lena , Beury Manon
Published: January 2022

The pioneering 1990s movement in critical theory has generated path-breaking scholarship seeking to queer law. Efforts to queer international law have produced important research uncovering the role of international law as a performative discourse and as a transnational governance framework reproducing gendered and sexual hegemonies. However, these efforts have done very little to destabilize the structures and workings of the very site where international law is theorized and taught: the university. Queering international law has mostly entailed looking at how the state, international organizations, international lawyers, scholars, and civil society produce or resist the heteronormative matrix, “that grid of cultural intelligibility through which bodies, genders, and desires are naturalized.” But what about the role of the university and its everyday routines––themselves byproducts of the aforementioned matrix––in reproducing and/or resisting (gendered) hierarchies and exclusions? We have raised this question as young scholars involved in organizing a week-long event on queer methods in international legal scholarship. The present essay is a first attempt at grappling with what the queering of an academic conference in international law meant for us, and for the university itself. It echoes a recent trend in scholarship on queer pedagogies, which, however, remain mostly silent on practices of scientific exchange. By reflecting on our efforts to queer a workshop in the field of international law, we also hope to inspire others to pursue their own queer processes of knowledge production.
Experimental and numerical study of laser-induced secondary jetting
Authors: Cerbus R.T. , Chraibi H. , Tondusson M. , Petit S. , Soto D. , Devillard R. , Delville J.P. , Kellay H.
Published: January 2022

The generation of liquid jets and drops using tightly focused femtosecond laser pulses near a liquid–air interface is a convenient contactless solution for printing functional materials as well as bio-materials. Jets and drops emerge following the nucleation of a cavitation bubble in the liquid bulk by a laser-induced plasma. During the initial expansion of the bubble, a thin and fast jet is produced at the liquid surface. Moments later a second thick and slow jet emanates from the surface when the bubble has nearly deflated. Despite potential applications, little is known about the mechanism behind this complex phenomenology. Here, experiments and simulations are used to investigate this two-jet process. Counter-intuitively, the second jet is not the result of bubble expansion, as with the first jet, but originates from the secondary flows induced by the bubble dynamics. Our study links the second jet properties to the control parameters of the problem and establishes a phase diagram for its emergence.
Foreign Acquisition and Credit Risk: Evidence from the U.S. CDS Market
Authors: Yilmaz Umit
Published: January 2022

This article empirically analyzes the effect of foreign block acquisitions on U.S. target firms’ credit risk as measured by their credit default swap (CDS) spreads. Foreign block purchases lead to a greater increase in the target firms’ CDS premia post-acquisition compared to domestic block purchases. This effect is stronger when foreign owners are geographically and culturally more distant, and when they obtain majority control. The findings are consistent with an asymmetric information hypothesis, in which foreign owners are less effective monitors due to information barriers.
Improving Access to Psychological Therapies (IAPT) services outcomes for people with learning disabilities: national data 2012–2013 to 2019–2020
Authors: Dagnan Dave , Rodhouse Caroline , Thwaites Richard , Hatton Chris
Published: January 2022

Primary care interventions for people with common mental health problems in England are primarily delivered through Improving Access to Psychological Therapies (IAPT) services. One of the priorities for IAPT services is to reduce inequalities in access and outcomes for potentially disadvantaged populations. This paper uses national data from the years 2012–2013 to 2019–2020 to present a comparison of service process and therapy outcomes for people with learning disabilities. Annual data for people with learning disabilities, people with other recorded disabilities and people with no recorded disabilities were extracted from a publicly available, national data source. Data are presented graphically with relative risk calculated for each variable and year, and show a broadly similar pattern of waiting time access for people with learning disabilities and people with no disabilities, and a broadly similar proportion of people with learning disabilities and people with no disabilities who finish treatment. However, people with learning disabilities have poorer clinical outcomes than people with no disabilities. We discuss adaptations to IAPT processes and therapy provision that may further support people with learning disabilities’ access to IAPT services.

Key learning aims

(1)

To describe how IAPT services record disabilities, and in particular record whether a person identifies themselves as having a learning disability.1

(2)

To explore the differences in processes and therapy outcomes for people with learning disabilities compared with people with no disabilities and people with other disabilities.

(3)

To understand adaptations to IAPT processes and therapies that may make IAPT services more accessible to people with learning disabilities.
Parameter Uncertainty Quantification in an Idealized GCM With a Seasonal Cycle
Authors: Howland Michael F. , Dunbar Oliver R. A. , Schneider Tapio
Published: January 2022

Climate models are generally calibrated manually by comparing selected climate statistics, such as the global top‐of‐atmosphere energy balance, to observations. The manual tuning only targets a limited subset of observational data and parameters. Bayesian calibration can estimate climate model parameters and their uncertainty using a larger fraction of the available data and automatically exploring the parameter space more broadly. In Bayesian learning, it is natural to exploit the seasonal cycle, which has large amplitude compared with anthropogenic climate change in many climate statistics. In this study, we develop methods for the calibration and uncertainty quantification (UQ) of model parameters exploiting the seasonal cycle, and we demonstrate a proof‐of‐concept with an idealized general circulation model (GCM). UQ is performed using the calibrate‐emulate‐sample approach, which combines stochastic optimization and machine learning emulation to speed up Bayesian learning. The methods are demonstrated in a perfect‐model setting through the calibration and UQ of a convective parameterization in an idealized GCM with a seasonal cycle. Calibration and UQ based on seasonally averaged climate statistics, compared to annually averaged, reduces the calibration error by up to an order of magnitude and narrows the spread of the non‐Gaussian posterior distributions by factors between two and five, depending on the variables used for UQ. The reduction in the spread of the parameter posterior distribution leads to a reduction in the uncertainty of climate model predictions.
Slip Rates Along the Laohushan Fault and Spatial Variation in Slip Rate Along the Haiyuan Fault Zone
Authors: Liu Jinrui , Ren Zhikun , Zhang Huiping , Li Chuanyou , Zhang Zhuqi , Zheng Wenjun , Li Xuemei , Liu Caicai
Published: January 2022

The spatial pattern of slip rates along the Haiyuan fault zone may reveal deformation process along the northeastern margin of the Tibetan Plateau. By applying the 3D_Fault_Offsets code, we reevaluated the displacements of offset markers displaced by the Laohushan fault, the central segment of the Haiyuan fault zone. We introduced the Bayesian Age Model approach to provide optimum age control for the preserved offset markers. Multiple offsets and ages constrain the late Pleistocene slip rate to 4.4–4.8 mm/yr. The spatial pattern of strike‐slip rates of the Haiyuan fault zone indicates that the Madongshan and Liupanshan could be the main uplifts that absorbed the left‐lateral motion along the Haiyuan fault zone, due to a restraining bend between the Haiyuan and Qishan‐Mazhao fault zones. Furthermore, uniform slip rates along the main segments and slip rates decreasing toward fault tips are widely observed along some intensively studied strike‐slip faults, such as the Altyn Tagh, Kunlun, Death Valley‐Fish Lake Valley, Denali, San Andreas and Alpine faults. The results suggest that the constancy or similarity of the slip rates along the strike is closely related to block rotation and internal deformation, and the slip rates of strike‐slip faults usually change at the fault tip area converting from horizontal to vertical motion. In addition, strike‐slip fault can also take slip off of the main fault and distribute it between multiple active parallel strands.
Large Herbivores May Improve an Ecosystem’s Carbon Persistence
Authors: Pardikar Rishika
Published: January 2022

The grazing habits of wild animals like elephants and boars enable long-term carbon storage, according to new research that stresses the need to align climate mitigation goals with biodiversity conservation.
Endometrial stromal cell ferroptosis promotes angiogenesis in endometriosis
Authors: Li Guojing , Lin Yu , Zhang Yili , Gu Nihao , Yang Bingxin , Shan Shan , Liu Na , Ouyang Jing , Yang Yisai , Sun Feng , Xu Hong
Published: January 2022

Endometriosis, a chronic disorder characterised by the presence of endometrial-like tissue outside the uterus, is associated with iron overload and oxidative stress in the lesion. Although it is well established that iron overload can trigger ferroptosis, the results of previous studies on ferroptosis resistance and ferroptosis in endometriotic lesions are paradoxical. Here, we found that some stromal cells of the cyst walls that were in contact with the cyst fluid underwent ferroptosis. Surprisingly, endometrial stromal cell ferroptosis triggered the production of angiogenic, inflammatory and growth cytokines. In particular, angiogenic cytokines, such as vascular endothelial growth factor A (VEGFA) and interleukin 8 (IL8), promoted human umbilical vein endothelial cell (HUVEC) vascular formation in vitro. Moreover, we found that inhibition of p38 mitogen-activated protein kinase/signal transducer and activator of transcription 6 (p38 MAPK/STAT6) signalling represses VEGFA and IL8 expression when endometrial stromal cells undergo ferroptosis. Notably, VEGFA and IL8 showed localised expression and were significantly upregulated in ectopic lesions compared to control and eutopic endometrium samples from patients with endometriosis. Thus, our study reveals that endometrial stromal cell ferroptosis in the ovarian endometrioma may trigger cytokine secretion and promote angiogenesis of adjacent lesions via paracrine actions to drive the development of endometriosis, providing a rationale for translation into clinical practice and developing drugs for endometriosis.
Revealing defective interfaces in perovskite solar cells from highly sensitive sub-bandgap photocurrent spectroscopy using optical cavities
Authors: van Gorkom Bas T. , van der Pol Tom P. A. , Datta Kunal , Wienk Martijn M. , Janssen René A. J.
Published: January 2022

Defects in perovskite solar cells are known to affect the performance, but their precise nature, location, and role remain to be firmly established. Here, we present highly sensitive measurements of the sub-bandgap photocurrent to investigate defect states in perovskite solar cells. At least two defect states can be identified in p-i-n perovskite solar cells that employ a polytriarylamine hole transport layer and a fullerene electron transport layer. By comparing devices with opaque and semi-transparent back contacts, we demonstrate the large effect of optical interference on the magnitude and peak position in the sub-bandgap external quantum efficiency (EQE) in perovskite solar cells. Optical simulations reveal that defects localized near the interfaces are responsible for the measured photocurrents. Using optical spacers of different lengths and a mirror on top of a semi-transparent device, allows for the precise manipulation of the optical interference. By comparing experimental and simulated EQE spectra, we show that sub-bandgap defects in p-i-n devices are located near the perovskite-fullerene interface.
Two opposing hippocampus to prefrontal cortex pathways for the control of approach and avoidance behaviour
Authors: Sánchez-Bellot Candela , AlSubaie Rawan , Mishchanchuk Karyna , Wee Ryan W. S. , MacAskill Andrew F.
Published: January 2022

The decision to either approach or avoid a potentially threatening environment is thought to rely upon the coordinated activity of heterogeneous neural populations in the hippocampus and prefrontal cortex (PFC). However, how this circuitry is organized to flexibly promote both approach or avoidance at different times has remained elusive. Here, we show that the hippocampal projection to PFC is composed of two parallel circuits located in the superficial or deep pyramidal layers of the CA1/subiculum border. These circuits have unique upstream and downstream connectivity, and are differentially active during approach and avoidance behaviour. The superficial population is preferentially connected to widespread PFC inhibitory interneurons, and its activation promotes exploration; while the deep circuit is connected to PFC pyramidal neurons and fast spiking interneurons, and its activation promotes avoidance. Together this provides a mechanism for regulation of behaviour during approach avoidance conflict: through two specialized, parallel circuits that allow bidirectional hippocampal control of PFC.