bluuebunny/crossref_metadata_2025 huggingface dataset:
Rhabdomyolysis and myoglobinuria following single induction dose of propofol in a dog
Authors: Cervone Mario , Nectoux Alexandra , Pouzot‐Nevoret Celine
Published: July 2022

Objective

To report a case of rhabdomyolysis and myoglobinuria following single induction dose of propofol in a dog.

Case Summary

A 5‐year‐old intact male Shih‐Tzu dog was presented for pigmenturia occurring a few hours following anesthesia for comprehensive oral health assessment and treatment. After premedication with IV diazepam (0.5 mg/kg), anesthesia was induced with IV propofol (4 mg/kg) and maintained with isoflurane vaporized in oxygen. A few hours following recovery from anesthesia, the dog developed rhabdomyolysis and myoglobinuria associated with increased serum alanine aminotransferase and C‐reactive protein concentrations, as well as mild hypokalemia and euglycemic glycosuria. Approximately 48 hours after IV fluid therapy, the dog was clinically normal, and myoglobinuria progressively resolved.

New or Unique Information Provided

This is the first case description of rhabdomyolysis and myoglobinuria following a single dose of injectable propofol.
Financial sustainability of rural water supply: An analysis of cost recovery, revenue collection, and efficiency
Authors: Mohanty Tapasi , Rout Himanshu Sekhar
Published: July 2022

Maintaining a financial sustainable pipe water supply (PWS) is one of the serious challenges in sustainable provision of water supply in rural areas. Poor revenue collection and willingness to pay for the service is adding severity to the problem. This study analyses the factors affecting revenue collection in rural water utilities and measures its efficiency in maximizing revenue and average hour of water supply per day. The findings convey that cost recovery is a failure in rural water supply even they are not able to generate revenue. Inactive community participation, the notion of free water supply, unaccountable payment is main reason for poor revenue collection. Therefore, active community participations, educating the household on water supply, adoption of accountable payment mode will be a step towards revenue generation. To attain efficiency, the utilities can expand their output revenue and hours of water supply by 22% without altering their input. This study is an empirical contribution in the field of sustainable provision of water supplies, which address the problem of poor revenue generation in rural water supply and find out the reason for it.
Visualising and quantifying microvascular structure and function in patients with heart failure using optical coherence tomography
Authors: Sciarrone David F. G. , McLaughlin Robert A. , Argarini Raden , To Minh‐Son , Naylor Louise H. , Bolam Lucy M. , Carter Howard H. , Green Daniel J.
Published: July 2022

Heart failure (HF) is characterised by abnormal conduit and resistance artery function in humans. Microvascular function in HF is less well characterised, due in part to the lack of tools to image these vessels in vivo. The skin microvasculature is a surrogate for systemic microvascular function and health and plays a key role in thermoregulation, which is dysfunctional in HF. We deployed a novel optical coherence tomography (OCT) technique to visualise and quantify microvascular structure and function in 10 subjects with HF and 10 age‐ and sex‐matched controls. OCT images were obtained from the ventral aspect of the forearm, at baseline (33°C) and after 30 min of localised skin heating. At rest, OCT‐derived microvascular density (20.3 ± 8.7%, P = 0.004), diameter (35.1 ± 6.0 μm, P = 0.006) and blood flow (82.9 ± 41.1 pl/s, P = 0.021) were significantly lower in HF than CON (27.2 ± 8.0%, 40.4 ± 5.8 μm, 110.8 ± 41.9 pl/s), whilst blood speed was not significantly lower (74.3 ± 11.0 μm/s vs. 81.3 ± 9.9 μm/s, P = 0.069). After local heating, the OCT‐based density, diameter, blood speed and blood flow of HF patients were similar (all P > 0.05) to CON. Although abnormalities exist at rest which may reflect microvascular disease status, patients with HF retain the capacity to dilate cutaneous microvessels in response to localised heat stress. This is a novel in vivo human observation of microvascular dysfunction in HF, illustrating the feasibility of OCT to directly visualise and quantify microvascular responses to physiological stimuli in vivo.

image

Key points

Microvessels in the skin are critical to human thermoregulation, which is compromised in participants with heart failure (HF).

We have developed a powerful new non‐invasive optical coherence tomography (OCT)‐based approach for the study of microvascular structure and function in vivo.

Our approach enabled us to observe and quantify abnormal resting microvascular function in participants with HF.

Patients with HF were able to dilate skin microvessels in response to local heat stress, arguing against an underlying structural abnormality. This suggests that microvascular functional regulation is the primary abnormality in HF.

OCT can be used to directly visualise and quantify microvascular responses to physiological stimuli in vivo.
Performance Investigation of a Bladeless Air Compressor
Authors: Tiwari Ravi Nath , Reggio Federico , Renuke Avinash , Pascenti Matteo , Traverso Alberto , Ferrari Mario Luigi
Published: July 2022

This study aims to investigate the reversible operation of a bladeless air expander prototype operated reversibly in compressor mode to understand the performance by numerical method and compare its results experimentally. A bladeless machine can reverse its operation by simply inverting the rotational speed. However, expander and compressor performance may differ significantly since losses are exacerbated in the compressor mode. The prototype was previously tested as an expander (experimental highest isentropic efficiency of 36.5%). In this work, the reverse mode is discussed, when the prototype is actuated as a compressor, with and without diffuser at variable rotational speeds. In compressor mode, the fluid enters through the center axially, passes radially outwards through disk gaps, and exits throughout the diffuser. The momentum transfer and pressure gain are carried out by the shear force produced on the surface of the rotating disk. An experimental/theoretical analysis focused on the pressure ratio, mass flow, and efficiency of bladeless compressor is conducted. High losses (main leakage across the rotor) were noticed during the experiments, affecting the overall Tesla compressor performance. Numerical calculations are carried out to estimate leakage losses by comparison with experimental results. It is shown that the original expander design would require specific modifications to reduce end disk leakages, which are higher in compressor mode than in expansion mode, significantly affecting the elaborated net mass flow. Improved diffuser, scroll, disk end gaps, and sealing mechanisms are discussed in order to augment overall performance of the bladeless prototype in compressor mode.
Three-Dimensional Printing in Combined Cartesian and Curvilinear Coordinates
Authors: Shi Edward , Lou Leo , Warburton Linnea , Rubinsky Boris
Published: July 2022

A three-dimensional (3D) printing technology that facilitates continuous printing along a combination of Cartesian and curvilinear coordinates, designed for in vivo and in situ bioprinting, is introduced. The combined Cartesian/curvilinear printing head motion is accomplished by attaching a biomimetic, flexible, “tendon cable” soft robot arm to a conventional Cartesian three axis 3D printing carousel. This allows printing along a combination of Cartesian and curvilinear coordinates using five independent stepper motors controlled by an Arduino Uno with each motor requiring a microstep driver powered via a 12 V power supply. Three of the independent motors control the printing head motion along conventional Cartesian coordinates while two of the independent motors control the length of each pair of the four “tendon cables” which in turn controls the radius of curvature and the angle displacement of the soft printer head along two orthogonal planes. This combination imparts motion along six independent degrees-of-freedom in Cartesian and curvilinear coordinates. The design of the system is described together with experimental results, which demonstrate that this design can print continuously along curved and inclined surfaces while avoiding the “staircase” effect, which is typical of conventional three axis 3D printing along curvilinear surfaces.
Torsional Wave Propagation and Vibration Reducing of Phononic Crystal Pipe With Periodic Torsional Support
Authors: Wu Jiang-hai , Zhu Hong-zhen , Sun Yu-dong , Su Ming-zhu , Yin Zhi-yong
Published: July 2022

In this paper, torsional vibration band gap properties of a fluid filled pipe were studied by using the transfer matrix method (TMM). By comparing the results obtained from the fem software, the established torsional dynamic model and the proposed method were verified. The effects of pipe wall's material and parameters of support on the torsional vibration band gap properties were analyzed. Furthermore, the relationship between torsional displacement and vibration band gaps was investigated. These attenuation regions of responses show good agreement with the frequency of Bragg band gaps. Explained the locally resonant (LR) phononic crystals (PCs) band gaps form mechanism from the point of mechanical impedance mismatch theory, the results show that the peak frequency of impedance mismatch defines the beginning of both LRs and Bragg band gaps. In essence, the locally resonant is the same as periodic support from the impedance theory. The results of this paper could give some valuable suggestions on the vibration control of the pipeline system.
Flow Control for a Submerged Inlet
Authors: Xie Wenzhong , Zeng Cheng , Wang Zhenyu , Guo Shengmin
Published: July 2022

Submerged inlets have the advantages of low drag, clean outer profile, and excellent stealth performance. Previous studies indicate that the zones of large total-pressure loss, located at the bottom and top regions of the exit plane, are the main cause of the poor aerodynamic performance in a submerged inlet. To improve the performance, a flow-control method is proposed in this paper, which includes both ramp side boundary layer bleeding and entrance side-edge vortex diverting. With numerical simulations, the efficacy of the proposed flow control is examined by comparing the aerodynamic performance and flow-field pattern of a baseline inlet and a controlled inlet over the typical flight envelope. The results prove that the proposed flow-control method can effectively discharge the low-energy flow of the forebody boundary layer on the ramp and isolate the major low-energy flow of the side-edge vortex. The proposed flow-control method results in a large improvement in the aerodynamic performance over the whole flight envelope. Specifically, the total pressure recovery (σ) of the inlet with the proposed flow-control features raises 3.06%, and the distortion (DC60) and the swirl distortion (SC60) lessen by 72.57% and 17.73%, respectively, in contrast to the baseline inlet under the engine matching point of cruise state (Ma0=0.72, α=2 deg, β=0 deg, Ma2=0.39).
Is Motor Coordination the Key to Success in Youth Cycling?
Authors: Mostaert Mireille , Vansteenkiste Pieter , Laureys Felien , Rommers Nikki , Pion Johan , Deconinck Frederik J.A. , Lenoir Matthieu
Published: July 2022

Purpose: To evaluate the predictive value of a (non-)sport-specific test battery on the future success of young cyclists, test scores were compared with competition performances 2–3 years later. Methods: Three motor coordination, 5 physical performance, and 2 cycling-specific measurements were collected in 111 U15 (13.0–14.9 y) and 67 U17 (15.0–16.9 y) male road cyclists. In addition, maturity status, relative age, and competition history were assessed. National and provincial competition results 2–3 years later, in the U17year2 and U19year2 categories, were submitted to 2 separate 4-stage hierarchical regressions. Results: The results of the model of the U15 group revealed that maturity, relative age, competition history, motor coordination, physical performance, and cycling-specific performance accounted for 22.6% of the variance in competitive success. For the U15 category, only maturity and motor coordination were significant predictors of competitive success in the U17year2 category. Maturity and motor coordination each uniquely explained ±5% of the variance. However, for the U17 group—neither motor coordination, physical performance, nor cycling-specific performance could predict competitive success in the U19year2 category. Conclusions: The current study underlines the importance of general motor coordination as a building block necessary for optimal development in youth cycling. However, considering the lack of predictive value from the U17 category onward, other features may determine further development of youth athletes. Nevertheless, it is questioned why athletes need to possess a minimum level of all physical, motor coordination, and cycling-specific characteristics to experience success and enjoyment in their sport.
Does 8 Weeks of Integrated Functional Core and Plyometric Training Improve Postural Control Performance in Young Rhythmic Gymnasts?
Authors: Cabrejas Cristina , Morales Jose , Solana-Tramunt Mónica , Nieto-Guisado Ainhoa , Badiola-Zabala Alesander , Campos-Rius Josep
Published: July 2022

It has been suggested that core stability and plyometric training (CPT) can enhance athletes’ postural control. Nevertheless, the effects of an integrated core and plyometric training program on rhythmic gymnastics (RG) performance are unclear. This study aimed to evaluate the effects of an integrated functional CPT program on young rhythmics gymnasts’ postural performance. A sample of 44 young female rhythmic gymnasts from a competitive team (age = 10.5 ± 1.8 years) participated in the study. The subjects were randomly divided into a control group and an experimental group. Pre- and posttest design was used. Postural control was assessed using single-leg stance tests and RG-specific balances over a force platform and evaluated by expert RG judges. The experimental group (n = 23) completed an 8-week functional CPT program based on RG technical requirements. Meanwhile, the control group (n = 21) received their usual training sessions. A mixed model of analysis of variance was applied to evaluate the effects of an intrasubject factor and an intersubject factor on each of the dependent variables. After 8 weeks, the experimental group obtained significant better results in some variables of the right support leg with eyes open and left support leg with eyes open single-leg support (p < .01), improvements were also found in some specific RG balances: Arabesque measured on the force platform (p < .01) and the side leg with help balance scored by the judges (p < .01). In conclusion, an integrated functional CPT program improved postural control in young rhythmic gymnasts. Coaches should consider using this CPT to improve RG performance.
Experiences of Normalization of Pain and Injury in Elite Adolescent Basketball
Authors: Joncheray Helene , Chavinier-Réla Sabine , Burlot Fabrice , Dalgalarrondo Sébastien , Fukazawa-Couckuyt Stéphane
Published: July 2022

The objective of this article was to describe the experiences of normalization of pain and injuries among elite adolescent basketball players and their staff. A total of 10 elite adolescent basketball players, ages 15–17 years and eight members of their staff, were interviewed. Results showed that (a) for both players and staff, being able to normalize pain is considered as a necessity and requires experience; injury is regarded as inevitable and as a way to gain body expertise and (b) technical and medical staffs have difficulties in agreeing on pain and injury management. The originality of the results presented lies in the fact that the elite players interviewed are in training; and that the expectations of the players, the technical staff, and the medical staff were questioned at the same time.
2D Integrable systems, 4D Chern–Simons theory and affine Higgs bundles
Authors: Levin A. , Olshanetsky M. , Zotov A.
Published: July 2022

We compare the construction of 2D integrable models through two gauge field theories. The first one is the 4D Chern–Simons (4D-CS) theory proposed by Costello and Yamazaki. The second one is the 2D generalization of the Hitchin integrable systems constructed by means of affine Higgs bundles (AHB). We illustrate the latter approach by considering 1 + 1 field versions of integrable systems including the Calogero–Moser field theory, the Landau–Lifshitz model and the field theory generalization of the elliptic Gaudin model.
Constraining wormhole geometries using the orbit of S2 star and the Event Horizon Telescope
Authors: Jusufi Kimet , Kumar Saurabh , Azreg-Aïnou Mustapha , Jamil Mubasher , Wu Qiang , Bambi Cosimo
Published: July 2022

In this paper we study the possibility of having a wormhole (WH) as a candidate for the Sgr A$$^\star $$

⋆

central object and test this idea by constraining their geometry using the motion of S2 star and the reconstructed shadow images. In particular, we consider three WH models, including WHs in Einstein theory, brane-world gravity, and Einstein–Dirac–Maxwell theory. To this end, we have constrained the WH throat using the motion of S2 star and shown that the flare out condition is satisfied. We also consider the accretion of infalling gas model and study the accretion rate and the intensity of the electromagnetic radiation as well as the shadow images.
Differential scattering in proton collisions with molecular hydrogen
Authors: Plowman Corey T. , Abdurakhmanov Ilkhom B. , Bray Igor , Kadyrov Alisher S.
Published: July 2022

The recently developed two-centre wave-packet convergent close-coupling approach to proton collisions with molecular hydrogen is applied to calculate various singly differential cross sections. The approach is based on an effective one-electron description of the $${\hbox {H}_2}$$

H
2

target. The angular differential cross sections for elastic scattering, total excitation and electron capture are presented. Furthermore, we calculate the singly differential ionisation cross sections as functions of the ejected-electron energy and angle, as well as projectile scattering angle. Good agreement with available experimental data is observed, providing improvement over previous theoretical investigations into the singly differential cross section for ionisation. Specific mechanisms responsible for electron emission in particular kinematic regimes are identified. It is concluded that the effective one-electron WP-CCC method is capable of providing reasonably accurate results on singly differential cross sections for all included interconnected processes taking place in $${\hbox {p}}+{\hbox {H}_2}$$

p
+

H
2

collisions.

Graphic abstract
Comparing pulsed and continuous laser-induced acoustic desorption (LIAD) as sources for intact biomolecules
Authors: Wang Siwen , Abma Grite L. , Krüger Peter , van Roij Andre , Balster Michiel , Janssen Niek , Horke Daniel A.
Published: July 2022

A major obstacle to the gas-phase study of larger (bio)molecular systems is the vaporisation step, that is, the introduction of intact sample molecules into the gas-phase. A promising approach is the use of laser-induced acoustic desorption (LIAD) sources, which have been demonstrated using both nanosecond pulsed and continuous desorption lasers. We directly compare here both approaches for the first time under otherwise identical conditions using adenine as a prototypical biological molecule, and study the produced molecular plumes using femtosecond multiphoton ionisation. We observe different desorption mechanisms at play for the two different desorption laser sources; however, we find no evidence in either case that the desorption process leads to fragmentation of the target molecule unless excessive desorption energy is applied. This makes LIAD a powerful approach for techniques that require high density and high purity samples in the gas-phase, such as ultrafast dynamics studies or diffraction experiments.

Graphic abstract
Ultrathin coding metasurface for underwater wave focusing, branching and self-bending generation with one single actuator
Authors: Song Lixie , Chen Zhong , Negahban Mehrdad , Liang Lei , Li Zheng , Wu Zheng
Published: July 2022

A novel metasurface is proposed that aims to generate underwater acoustic waves with various functions by only one actuator. Each metasurface unit consists of an air cavity sandwiched on one side by a vibration plate and connecting rubber supports. By properly selecting the ratio of the plate to unit lengths, a phase shift of [Formula: see text] can be attained to constitute a binary coding metasurface. Three demonstrations, including focusing, branching and self-bending waves, are chosen to validate the functionality of the design. The design is also shown to work over a wide frequency range by changing the ratio. In addition, the design is extremely compact, with the thickness only about 1/100 of the target wavelength. Compared with commonly used phased array transducers that are utilized to generate underwater acoustic waves, this design offers has the advantage of needing only a single actuator as opposed to needing a lumped electrical control system.
Simulation of hyperbolic type solitary waves based on velocity parameter for (3 + 1)-dimensional the B-type Kadomtsev–Petviashvili–Boussinesq equation
Authors: Yokuş Asıf , Aydın M. Evren , Duran Serbay , Durur Hülya
Published: July 2022

In this paper, we investigate solutions to the [Formula: see text]-dimensional B-type Kadomtsev–Petviashvili–Boussinesq (B-KPB) equation, which has strong nonlinearity feature by using sub-equation and the modified [Formula: see text]-expansion methods. Using these analytical methods, dark soliton, trigonometric oscillation, singular soliton, algebraic and hyperbolic type oscillating traveling wave solutions are presented. By giving special values to the parameters in the obtained traveling wave solutions, 3D, 2D and contour graphs representing the solitary waves are drawn. The advantages and disadvantages of both analytical methods are presented in comparison with each other. In addition, the changes of the solutions of the B-KPB equation according to the velocity parameter and the refraction phenomenon are supported by simulation. In addition, the solutions of the equation discussed are first discussed in detail, physical interpretations. Secondly, the geometric interpretations of the traveling wave solutions are analyzed and it is shown that the graphs of the solutions correspond to flat hyper-surfaces. It is argued that these hyper-surfaces can be leveled on a hyperplane without distortion.
A 1–3 GHz CMOS mixer-first receiver frontend with dual-feedback OTA achieving 306 MHz IF bandwidth, 2.1 dB NF, and 33 dB gain
Authors: Guo Benqing , Wang Haishi , Wang Huifen , Wang Yao
Published: July 2022

In this paper, a mixer-first receiver frontend with dual-feedback baseband is proposed. The negative resistive and positive capacitive feedback paths are both applied to single-stage inverter-based operational transconductance amplifier (OTA) with fewer poles, to cover a wide BB frequency range. The [Formula: see text]-path filtering at the RF side and second-order filtering at the BB side inhibit out-of-band blocker interferences. The receiver frontend is designed in 65 nm CMOS. Simulation results display an NF of 2.1 dB across 306 MHz IF bandwidth, and a maximum gain of 33 dB from 1 to 3 GHz LO frequency range. The in-band and out-of-band IIP3 are -13 and 16 dBm, respectively. The receiver core draws 40 mW at 1 GHz LO frequency.
Manipulations of cold atoms in a one-dimensional ring lattice
Authors: Zhang Shan , Wang Zezhou , Liu Junjun , Cui Bo
Published: July 2022

The dynamics of Bose–Einstein condensates in a one-dimensional ring optical lattice is related to the interplay of the open system conditions and the initial atomic distribution. The circulation evaluation model based on the relative atomic density on each site is established to analyze the circulation strength under low dissipation. The direction of the circulation due to the symmetry breaking can be manipulated by changing the primary atomic distribution and the number of lattice sites. The effect of the atomic interaction on the atom flow in the optical ring lattice is analyzed to maintain the current interval rotation behavior.
New behavior of tsunami and tidal oscillations for Long- and short-wave interaction systems
Authors: Tarla Sibel , Ali Karmina K. , Yilmazer Resat , Yusuf Abdullahi
Published: July 2022

The Jacobi elliptic function expansion method is one of the most powerful tools for exploring exact solutions of nonlinear partial differential models, which is used in this work to characterize the interaction between one long longitudinal wave and one short transverse wave propagation in a generalized elastic medium. First, we applied a wave transform to the proposed system of equations and obtained an ordinary differential equation. We obtain the values of involved free parameters after performing necessary operations, then substitute the obtained values to the ordinary differential equation by considering the constructed solutions to the ordinary and then to the partial differential equation. As a result, different structures of solutions are constructed such as solitary dark–bright, dark, bright, singular, trigonometric function, Jacobi elliptic function, and hyperbolic function solutions. In order to illustrate the tsunami and tidal oscillations, we draw 3D surfaces and 2D graphics for the obtained solutions by giving a specific value for the involved parameters under the given conditions.
TimeStitch: Exploiting Slack to Mitigate Decoherence in Quantum Circuits
Authors: Smith Kaitlin N. , Ravi Gokul Subramanian , Murali Prakash , Baker Jonathan M. , Earnest Nathan , Javadi-Cabhari Ali , Chong Frederic T.
Published: July 2022

Quantum systems have the potential to demonstrate significant computational advantage, but current quantum devices suffer from the rapid accumulation of error that prevents the storage of quantum information over extended periods. The unintentional coupling of qubits to their environment and each other adds significant noise to computation, and improved methods to combat decoherence are required to boost the performance of quantum algorithms on real machines. While many existing techniques for mitigating error rely on adding extra gates to the circuit [
13
,
20
,
56
], calibrating new gates [
50
], or extending a circuit’s runtime [
32
], this article’s primary contribution leverages the gates already present in a quantum program without extending circuit duration. We exploit circuit slack for single-qubit gates that occur in idle windows, scheduling the gates such that their timing can counteract some errors.

Spin-echo corrections that mitigate decoherence on idling qubits act as inspiration for this work. Theoretical models, however, fail to capture all sources of noise in Noisy Intermediate Scale Quantum devices, making practical solutions necessary that better minimize the impact of unpredictable errors in quantum machines. This article presents TimeStitch: a novel framework that pinpoints the optimum execution schedules for single-qubit gates within quantum circuits. TimeStitch, implemented as a compilation pass, leverages the reversible nature of quantum computation to boost the success of circuits on real quantum machines. Unlike past approaches that apply reversibility properties to improve quantum circuit execution [
35
], TimeStitch amplifies fidelity without violating critical path frontiers in either the slack tuning procedures or the final rescheduled circuit. On average, compared to a state-of-the-art baseline, a practically constrained TimeStitch achieves a mean 38% relative improvement in success rates, with a maximum of 106%, while observing bounds on circuit depth. When unconstrained by depth criteria, TimeStitch produces a mean relative fidelity increase of 50% with a maximum of 256%. Finally, when TimeStitch intelligently leverages periodic dynamical decoupling within its scheduling framework, a mean 64% improvement is observed over the baseline, relatively outperforming stand-alone dynamical decoupling by 19%, with a maximum of 287%.
Rhabdomyosarcoma-Induced Uterine Inversion
Authors: Li Kin , Davis Gavin , Wittenberg Colleen , Abidi Alireza
Published: July 2022

Nonpuerperal uterine inversion is a rare clinical condition that involves prolapse of the uterine fundus into the uterine cavity and vaginal vault and possibly passed the introitus. The majority of these cases commonly involve benign tumors such as leiomyoma. However, another common cause of nonpuerperal uterine inversion is due to malignancies such as sarcomas. Rhabdomyosarcoma is a rare and aggressive malignancy of soft tissue cells that are common in children and rare in adults. One subtype called embryonal rhabdomyosarcoma is exceptionally rare. Therefore, report of embryonal rhabdomyosarcoma-induced uterine inversion is an exceedingly scarce and rarely documented clinical condition. In this case report, we present a rare case of a nulliparous 27-year-old female who presented with embryonal rhabdomyosarcoma-induced uterine inversion.
Retrospective Study of the Application Value Analysis of Ultrasound-Guided Technology in Peripheral Deep Venous Catheterization of Neonates
Authors: Yin Tingting , Huo Yuan , Zhao Yang , Li Weiyang , Gao Hongxia
Published: July 2022

Objective. To investigate the application value analysis of ultrasound-guided technology in peripheral deep venous catheterization of neonates. Method. A total of 94 neonates who underwent peripheral deep venous catheterization treatment from March 2020 to August 2021 in our hospital were selected and divided into the study group and the control group according to the simple randomized method, and each group had 47 cases. The control group was performed peripheral deep venous catheterization through X-ray examination, while the study group was performed peripheral deep venous catheterization through ultrasound-guided technology. The catheter placement, catheter retention time and adjustment times, the incidence of complications (limb swelling, pain, fluid leakage, and phlebitis), and the intervention satisfaction of family members were counted. Results. The success rate of one-time catheterization in the study group was higher than that in the control group, the operation time was shorter than that in the control group, and the amount of bleeding was less than that in the control group. The indwelling time of catheter in the study group was longer than that in the control group, and the number of adjustments was less than that in the control group. The incidence of complications in the study group was lower than that in the control group. The intervention satisfaction of family members in the study group was higher than that in the control group. Conclusion. Peripheral deep venous catheterization in neonates through ultrasound-guided technology can reduce operation time and blood loss and ensure the success rate of one-time catheterization, resulting in a long indwelling time of catheter, low number of adjustments, and low incidence of complications, which has safety and high intervention satisfaction of family members.
Tracheoesophageal Diversion and Laryngotracheal Separation Procedures for Radiotherapy‐Related Intractable Aspiration Pneumonia in Nasopharyngeal Carcinoma
Authors: Gu Wei , Wang Jian
Published: July 2022

Background. Intractable aspiration and aspiration pneumonia are complications after radiotherapy for nasopharyngeal carcinoma (NPC), and they may be life‐threatening in severe cases. In the past, the efficacy of controlling aspiration and aspiration pneumonia in such patients was not ideal. Objectives. We aimed to evaluate the effect of tracheoesophageal diversion and laryngotracheal separation (TED‐LTS) procedures for these patients. Material and Methods. We retrospectively analyzed the medical data of five patients with intractable aspiration and recurrent aspiration pneumonia caused by NPC radiotherapy who underwent TED‐LTS surgery. The patients were evaluated in terms of aspiration pneumonia control, body weight improvement, removal of tube feeding, oral feeding, and complications. Results. Intractable aspiration and aspiration pneumonia were completely controlled in all cases, and the patients’ body weight increased from 46.46 ± 4.6 (38.9‐50.3) kg to 55.32 ± 2.7 (51.4‐56.7) kg. Four patients were able to consume an oral semisolid diet, and one patient maintained an oral liquid diet. Tube feeding was not required in 4 patients. One patient developed postoperative esophageal fistula, which improved after conservative treatment. Conclusion. TED‐LTS is effective for intractable aspiration and aspiration pneumonia caused by NPC radiotherapy and can be used to restore partial oral feeding. However, strict surgical indications should be followed.
Gene Identification and Potential Drug Therapy for Drug-Resistant Melanoma with Bioinformatics and Deep Learning Technology
Authors: Liu Muge , Xu Yingbin
Published: July 2022

Background. Melanomas are skin malignant tumors that arise from melanocytes which are primarily treated with surgery, chemotherapy, targeted therapy, immunotherapy, radiation therapy, etc. Targeted therapy is a promising approach to treating advanced melanomas, but resistance always occurs. This study is aimed at identifying the potential target genes and candidate drugs for drug-resistant melanoma effectively with computational methods. Methods. Identification of genes associated with drug-resistant melanomas was conducted using the text mining tool pubmed2ensembl. Further gene screening was carried out by GO and KEGG pathway enrichment analyses. The PPI network was constructed using STRING database and Cytoscape. GEPIA was used to perform the survival analysis and conduct the Kaplan-Meier curve. Drugs targeted at these genes were selected in Pharmaprojects. The binding affinity scores of drug-target interactions were predicted by DeepPurpose. Results. A total of 433 genes were found associated with drug-resistant melanomas by text mining. The most statistically differential functional enriched pathways of GO and KEGG analyses contained 348 genes, and 27 hub genes were further screened out by MCODE in Cytoscape. Six genes were identified with statistical differences after survival analysis and literature review. 16 candidate drugs targeted at hub genes were found by Pharmaprojects under our restrictions. Finally, 11 ERBB2-targeted drugs with top affinity scores were predicted by DeepPurpose, including 10 ERBB2 kinase inhibitors and 1 antibody-drug conjugate. Conclusion. Text mining and bioinformatics are valuable methods for gene identification in drug discovery. DeepPurpose is an efficient and operative deep learning tool for predicting the DTI and selecting the candidate drugs.
Development of Modified LSTM Model for Reservoir Capacity Prediction in Huanggang Reservoir, Fujian, China
Authors: Dai Bibo , Wang Jiangbin , Gu Xiao , Xu Chunyan , Yu Xin , Zhang Haosheng , Yuan Canming , Nie Wen
Published: July 2022

The Huanggang Reservoir capacity is affected by a variety of factors. In order to accurately understand the Huanggang Reservoir capacity change, we develop a new hydrological prediction model based on the LSTM (Long-Short-Term Memory) method, which is used to predict the capacity of the reservoir. In this modified model, we choose to input multidimensional factors, two fully connected layers, selecting the optimal number of the hidden neurons, the optimizer, and adding the attention mechanism. The result of using the Developed LSTM and usual LSTM shows that the prediction curve of the Developed LSTM model can fit the true value better than the usual LSTM model, and the mean relative error of the Developed LSTM model decreased by 1.15%-3.82%, comparing with the usual LSTM model. Thus, we realize that the Developed LSTM model can make accurately prediction in some reservoir capacity estimations.
XBP1 Regulates the Transcription of HIF-1a in BALB/c Mice with Chronic Rhinosinusitis without Polyps
Authors: Qu Xiaopeng , Li Hongyan , Meng Lingzhao
Published: July 2022

X-box binding protein 1 (XBP1) is a transcription factor that recognizes the CRE-like element in enhancers of human T-cell leukemia virus and MHC class II gene and induces their transcription. This study was performed to characterize the function of XBP1, which was identified to be a differentially expressed gene via GEO database, in chronic rhinosinusitis (CRS) without nasal polyps (CRSsNP). XBP1 expression was significantly elevated in both CRSsNP patients and mice who were accompanied with mucosal thickening, goblet cell hyperplasia and chemosis, glandular hyperplasia, and dense infiltration of inflammatory cells. Silencing of XBP1 suppressed the development of CRSsNP in mice. Mechanistically, knockdown of XBP1 downregulated the expression of hypoxia-inducible factor 1-alpha (HIF-1a), and overexpression of XBP1 led to the opposite result. Silencing of HIF-1a inhibited β-catenin expression and impaired the Wnt/β-catenin pathway. Further overexpression of HIF-1a in XBP1-silenced CRSsNP mice exacerbated pathological changes in mouse nasal mucosal tissues, promoted inflammation, and activated the Wnt/β-catenin pathway. Taken together, overexpression of XBP1 may be associated with increased expression of HIF-1a and possibly contribute to the Wnt/β-catenin pathway activation and the development of CRSsNP.
[Retracted] Effect of Neoadjuvant Chemotherapy on Angiogenesis and Cell Proliferation of Breast Cancer Evaluated by Dynamic Enhanced Magnetic Resonance Imaging
Authors: Chang Lifang , Lan Honglin
Published: July 2022

Background. Breast cancer is the uncontrolled proliferation of breast epithelial cells under the action of various carcinogenic factors. The evaluation of early efficacy of neoadjuvant chemotherapy for breast cancer is helpful to change the treatment plan in time. On this basis, dynamic contrast enhancement magnetic resonance imaging (DCE‐MRI) was used to evaluate the effects of neoadjuvant chemotherapy on angiogenesis and cell proliferation in breast cancer. Objective. To evaluate the effect of neoadjuvant chemotherapy on angiogenesis and cell proliferation of breast cancer by dynamic enhanced DCE‐MRI. Method. 80 breast cancer patients were divided into the routine chemotherapy group (3 cycles) and neoadjuvant chemotherapy groups (3 cycles) of 40 cases each from January 2018 to June 2021. Based on conventional imaging, DCE‐MRI was performed with Intera Achieva 3.0 TMR superconducting MR scanner before and after treatment. The quantitative indexes, MRI parameters, cell proliferation expression, and DCE‐MRI angiogenesis were compared between the two groups. Result. The inhibition rate, Vepost, Ktranspre, ADC, Bax, Alexi, and Aurora in the neoadjuvant chemotherapy group were significantly higher than those in the conventional chemotherapy group (P < 0.05), while Kep, Ktrans, and Nek2 were significantly lower than those in the conventional chemotherapy group (P < 0.05). Vepre (cm3), Ktranspre (ml/min/100 cm3), and Ve had no significant difference (P > 0.05). Conclusion. The quantitative parameters, MRI parameters, proliferation, and expression of DCE‐MRI in breast cancer patients with different chemotherapy regimens are quite different. They can be applied to the diagnosis of neoadjuvant chemotherapy in breast cancer patients with angiogenesis and cell proliferation.
[Retracted] Influence of Nutritional Support Program on Gastrointestinal Function, Complication Rate, and Prognosis in Elderly Sufferers with CI
Authors: Zhang Huijuan , Yang Jun , Xiong Ying
Published: July 2022

To explore the effect of nutritional support program on gastrointestinal function, complication rate, and prognosis in elderly patients with cerebral infarction (CI), 200 elderly patients with CI from January 2020 to January 2021 are investigated in this study. The patients were randomly divided into a study set and a control group, with 100 cases in each set. All sets were given routine treatment, the control set was given parenteral nutrition support on a routine basis, and the study set was given enteral nutrition support on a routine basis. First, the clinical efficacy of the two sets after treatment was compared. Next, the constipation symptom score was adopted to compare the intestinal function of the two sets of patients before and after one month of treatment. The nutritional indicators, including serum albumin (ALB) and serum total protein (TP) levels, were compared between the two sets of patients before and after one month of treatment. Furthermore, the complications of the two sets of patients and the prognosis of the two groups of patients are analyzed. For elderly CI patients, enteral nutrition support therapy can significantly improve the clinical treatment effect, the gastrointestinal function, and nutritional index level. Also, it can reduce the incidence of complications and enhance the prognosis, survival rate, and quality of life.
The Improvement Effect of Online Teaching Based on Intelligent Speech Recognition Technology on the Teaching Management Mode in Colleges and Universities
Authors: Tian Tian
Published: July 2022

In order to improve the advanced nature of teaching management mode in colleges and universities, this paper analyzes the teaching management process in colleges and universities combined with intelligent speech recognition technology. For the dataset of linear teaching speech information distribution, in the case of overlapping of various datasets, this paper finds the overlapping points of various datasets through an algorithm. Moreover, this paper makes full use of the known information to find a vector that can equivalently represent the linear teaching speech information where each data point is located. After that, this paper takes it as the feature vector of each data point and then performs clustering through spectral clustering to obtain the clustering result. The experimental research results show that the model in this paper has a good effect on speech recognition in college teaching, and the model in this paper has a good role in promoting teaching management in colleges and universities.
Automatic Modulation and Recognition of Robot Communication Signal Based on Deep Learning Neural Network
Authors: Zou Xiaoguang , Zou Xiaoyong
Published: July 2022

In order to solve the problem that the traditional method of manually extracting expert features for communication signal recognition has large limitations and low accuracy under low signal-to-noise ratio, this paper proposes an automatic modulation and recognition method of robot communication signal based on deep learning neural network. In this method, the received signal is preprocessed to obtain the complex baseband signal including in-phase component and quadrature component. The signal is used as the data set of the input convolution neural network model. The model structure and the super parameters such as convolution kernel, step size, characteristic graph, and activation function are adjusted through multiple training, and the trained model is used to extract and recognize the features of the communication signal. It realizes the identification and classification of seven types of digital communication signals: 2FSK, 4FSK, BPSK, 8PSK, QPSK, QAM16, and QAM64. The experimental results show that the average recognition accuracy of the seven signals has reached 94.61% when the signal-to-noise ratio is 0 dB. Conclusion. The algorithm is proved to be effective and has high accuracy under the condition of low signal-to-noise ratio.
Influence of Open Apex on Working Length Determination Using Cone‐Beam Computed Tomography and Apex Locators: A Comparative In Vitro Study
Authors: Srivastava Swati , Alharbi Hanan M. , Soliman Mai , Eldwakhly Elzahraa , Abdelhafeez Manal M.
Published: July 2022

Objectives. The aim of this study is to assess the effect of open apex on working length (WL) determination with aid of cone‐beam computed tomography (CBCT) and electronic apex locators (EALs). Methods. Thirty‐two extracted human mandibular premolars were selected, and apical 5 mm was removed. Root canals were prepared from the apical to the coronal direction of the canal using peeso reamers up to size 5 (retrograde) to simulate open apex. The samples were analyzed by CBCT, and WL was established (CWL) by a radiologist. An endodontist prepared the access cavities, and visual working length (VWL) was recorded. The samples were embedded in a freshly mixed alginate mould up to cementoenamel junction. Each root canal length was measured with two different EALs—Root ZX mini and i Root. The measurements were repeated 3 times by using a digital caliper, and the mean was recorded by the endodontist who was blinded to the results of the CWL. The recorded data was statistically analyzed using the SPSS software. Results. The results of this study showed statistically significant difference between VWL and i Root, CWL and i Root, and Root ZX mini and i Root (p < 0.05). Amongst EALs, a superior accuracy was noted for Root ZX mini than as compared to i Root. However, no statistically significant difference was seen between Root ZX mini and CWL (p > 0.05). Conclusion. The present study showed that CWL is as accurate and reliable as VWL which is the gold standard. Amongst EALs, Root ZX mini performed more accurately than i Root. Preexisting CBCT scans should be used as an advantage in determining WL.
Mathematical Modeling Analysis of Data Attribute Encryption for Robot
Authors: Sun Jingyi , Yan Jie , Yang Dingyi
Published: July 2022

Encrypting data based on the data attributes of robots is one of the effective methods to control access users in the data outsourcing environment. Therefore, a mathematical modeling method of robot data attribute encryption based on data redundancy elimination technology is proposed. The encryption algorithm structure is analyzed based on the Bloom filter. The Hamming distance is used to calculate the similarity of big data by the Bloom filter. Finally, a big data ellipse encryption algorithm is designed according to the calculation results. The results show that during the whole experiment, the approximate fluctuation range is 0.08%~0.14%, which is not only high but also has a large fluctuation range. In contrast, the probability of occurrence of redundant data is less than 0.05% under different byte rates of redundant data, which is far lower than the two traditional methods, indicating that the application performance of the proposed method is good.