bluuebunny/crossref_metadata_2025 huggingface dataset:
Validation of a structural model of an aircraft cockpit panel: An industrial case study
Authors: Patterson Eann A , Diamantakos Ioannis , Dvurecenska Ksenija , Greene Richard J , Hack Erwin , Lampeas George , Lomnitz Marek , Siebert Thorsten
Published: November 2021

Computational models of structures are widely used to inform decisions about design, maintenance and operational life of engineering infrastructure, including airplanes. Confidence in the predictions from models is provided via validation processes that assess the extent to which predictions represent the real world, where the real world is often characterised by measurements made in experiments of varying sophistication dependent on the importance of the decision that the predictions will inform. There has been steady progress in developing validation processes that compare fields of predictions and measurements in a quantitative manner using the uncertainty in measurements as a basis for assessing the importance of differences between the fields of data. In this case study, three recent advances in a validation process, which was evaluated in an inter-laboratory study 5 years ago, are implemented using a ground-test on a fuselage at the aircraft manufacturer’s site for the first time. The results show that the advances successfully address the issues raised by the inter-laboratory study, that the enhanced validation process can be implemented in an industrial environment on a complex structure, and that the model was an excellent representation of the measurements made using digital image correlation.
Effects of employee engagement on customer responses: Examining the mediating role of customer engagement
Authors: Rabbanee Fazlul K , Ramaseshan B , Vyravene Revadee
Published: November 2021

Drawing on emotional contagion theory, this study offers an integrated framework showing the effects of employee engagement (EE) on customer engagement (CE), repeat purchase and word-of-mouth (WOM). The data were collected from 65 employees and 352 customers of 28 retail stores using 2 separate survey instruments. A dyadic data set was created by matching customer data with the employee data corresponding to each store. The findings reveal that two key facets of EE – dedication and absorption – positively influence CE, which eventually influences WOM and repeat purchase. In line with balance theory, CE is found to fully mediate the effects of absorption on WOM and repeat purchase. Furthermore, employee length of service (ELS) is found to moderate the absorption on CE effects. Thus, the findings extend emotional contagion theory and balance theory by providing empirical evidence supporting the differential effects of the facets of EE on CE en route to WOM and repeat purchase.

JEL Classification: M31
Solid waste dumping site analysis using GIS and remote sensing: Bonga Town, Southwestern Ethiopia
Authors: Biru Debalke Dereje , Endalew Admas Tesfahun
Published: November 2021

The main objective of this study was to select potential solid waste landfill areas suitable for Bonga Town that are environmentally sound. The key data were LANDSAT 8 and SPOT-6 satellite images with a spatial resolution of 15 and 1.5 m, respectively; a digital elevation model with a spatial resolution of 30 m; and a ground control point, which was collected through a ground point survey and a topographic map of the study area. Each parameter was subjected to a peer review according to the analytical hierarchy process. Once the weights were established, the weighted overlap analysis was determined, which combined these criteria and classified them into high, medium, less suitable and inappropriate regions of the study area. The results show that 75.65% of the study area is not suitable for the solid waste landfill, 18.86% less suitable, 5.17% moderately adequate and 0.3% very adequate. Therefore, the ability to use inaccessible geological information framework and detection innovations for mandatory discrimination evidence for a reasonably robust waste dump will minimise opportunities and natural human well-being problems.
A spatial decision support system for municipal solid waste landfill sites (case study: The Mazandaran Province, Iran)
Authors: Amirsoleymani Yasaman , Abessi Ozeair , Ghajari Yasser Ebrahimian
Published: November 2021

Landfilling is an inevitable step for the municipal solid waste (MSW) management system in developing countries. This article presents a Spatial Decision Support System (SDSS) that was developed for the monitoring of municipal landfills and siting the new places for waste disposal at Mazandaran province, south of Caspian Sea, Iran. The effective criteria and evaluation constraints were chosen according to the Iran waste management law. The ArcGIS 10.4.1 software was used for creating a geospatial database and the analytic hierarchy process (AHP) was used for ranking the criteria. By integrating the criteria, a suitability map was generated into four categories: high suitability, moderate suitability, low suitability and illegal areas. Using ArcGIS online, the maps were shared on a website that was specifically designed for this purpose. The decision-makers can check online the laws, the effective criteria and the results of spatial analysis for optimal siting. Also, the results of environmental evaluations for active landfills have been provided. Given the characteristics of active landfills and the optimal sites for the possible development, the SDSS can provide a mutually beneficial relationship between the experts, decision-makers and stakeholders to decide about the priority of actions required for the relocation of landfills, site closure or emergency care.
Postoperative Ecchymosis in Upper Blepharoplasty: A Split Face Study of Tranexamic Acid Versus Etamsylate
Authors: Fakih-Gomez Nabil , Steward Enosh , Bastidas Dario Andres , Manay Roshini , Zarate Juan Martin , Fakih-Gomez Ibrahim
Published: November 2021

Objective:

To compare the efficacy of tranexamic acid (TXA) versus etamsylate (ETM) in reducing postoperative ecchymosis in upper blepharoplasty.

Introduction:

With an increase in demand for shortened recoveries after facial aesthetic surgery, various optional approaches have been sought out. In terms of ecchymosis, TXA and ETM have been most commonly used.

Method:

A prospective, intrapatient split face study was conducted from January 2020 to January 2021 in 40 patients who underwent upper blepharoplasty under local anesthesia. Two equal anesthetic solutions were prepared; Solution A contained TXA and solution B contained ETM. Solution A was injected in the right eyelid and solution B in the left eyelid. Postoperative ecchymosis was assessed by 2 blinded evaluators, the assisting surgeon (Observer 1) and an external surgeon (Observer 2) at 48 h and on the seventh day using a scale published by Sagiv et al.

Results:

Postoperative ecchymosis was found to be less at 48 h by both observers with TXA solution. Moreover, at the seventh day, no ecchymosis was found in 32.5% with TXA solution compared to 2.5% with ETM solution. Kappa analysis showed concordance between observers.

Conclusion:

In our study, TXA solution was a more effective therapy when compared to ETM solution for reducing ecchymosis. Larger case studies are required to prove the difference for validation.
Measuring Scope of Practice Enactment Among Primary Care Registered Nurses
Authors: Braithwaite Suzanne , Tranmer Joan , Wilson Rosemary , Almost Joan , Tregunno Deborah
Published: November 2021

Background

Scope of practice enactment is poorly understood in the primary care setting.

Purpose

The following research objectives were addressed: (1) to revise and adapt the Actual Scope of Practice (ASCOP) questionnaire for use in the primary care setting, and (2) to determine internal consistency, construct validity, and sensitivity of the modified instrument.

Methods

To address the first objective, a narrative literature review and synthesis and an expert panel review was conducted. To address the second objective, a cross-sectional survey of 178 registered nurses who worked in primary care was conducted.

Results

The ASCOP, with few modifications, addressed key attributes of nursing scope of practice in the primary care setting. The modified instrument yielded acceptable alpha coefficients ranging from 0.66 to 0.91. Total mean score of 4.8 (SD  =  .67) suggests that registered nurses within interprofessional primary care teams almost always engage in activities reflected in the modified instrument.

Conclusions

The modified instrument is the first instrument validated to measure nursing scope of practice enactment in the primary care setting. Findings from this study support the use of the modified ASCOP questionnaire as a reliable and valid measure of scope of practice enactment among primary care registered nurses.
Porous membranes of quaternized chitosan composited with strontium-based nanobioceramic for periodontal tissue regeneration
Authors: Rajeswari Krishnankutty Adarsh , Najeema Sulaiman Shamna , Sadasivan Arun , Joseph Roy , Komath Manoj
Published: November 2021

This report demonstrates the development of a degradable quaternary ammonium derivative of chitosan (QC) composited with strontium-containing nanoapatite (SA) for bioactivity. The material was made as porous membrane by solution casting and freeze drying, for guided tissue regeneration (GTR) applications. The micromorphology, tensile strength, suture pull-out strength, degradation ( in vitro, in phosphate buffered saline), and cytocompatibility (using human periodontal ligament cells) were tested to investigate the effect of derivatization and SA addition. The porosity of the membranes increased with increasing SA content and so did the tensile strength and the degradation. The suture pull-out strength, however, showed a decrease. The cell culture evaluation endorsed biocompatibility. The composite with 1.5 mg SA per 1 mL QC was found to have optimal qualities for GTR applications.
Symptoms of Posttraumatic Stress and Sexual Concerns: The Intermediary Effects of Executive Functioning on Profiles of Youth Who Have Sexually Harmed
Authors: Brown Adam , Yoder Jamie
Published: November 2021

There are demonstrated links in the general population between developmental adversity, associated trauma symptoms, and executive functioning difficulties in children and youth. However, research on links among these indicators and their relationship to antisocial behavior more broadly in samples of youth who have sexually harmed is only beginning to emerge. Some research indicates that intermediary factors like sexual concerns may be critical in understanding this population. This study explored relationships between trauma symptoms, sexual concerns, executive functioning, and their relationship to non-sexual delinquency in a sample of 196 youth who committed sexual harm. Structural equation modeling revealed numerous direct and indirect effects on the path to delinquency and that executive functioning plays a key role among those with serious sexual concerns. The results are contextualized and implications are discussed.
Lessons Learned During Large-Scale Implementation Project Focused on Workplace Lactation Practices and Policies
Authors: Amanda Hickey  , Henning Margaret , Sirois Lissa
Published: November 2021

Purpose

This practice-based research funded by the Centers for Disease Control and Prevention (CDC) focuses on the translation of evidence-based practices and policies into real-world applications. To the best of our knowledge, this is the largest study to research the implementation process for lactation accommodations and policies for work sites.

Design or Approach

Pre-/post-test evaluation of work-site lactation accommodations, and 6-month follow-up with business that worked on the project.

Setting/Participants

34 businesses across New Hampshire.

Method

The team developed work-site selection criteria to award mini-grants; developed trainings and a toolkit; and worked with 34 businesses over a 3-year period. Pre-/post-implementation data were collected using the CDC work-site scorecard. A 6-month follow-up phone interview was conducted with each site.

Results

We assessed the CDC scorecard and evaluated the challenges of implementing lactation spaces by industry. In our 6-month follow-up, we found that spaces were still being utilized and we identified specific research to inform practical evidence-based applications and lessons learned when implementing a work-site lactation space.

Conclusion

We successfully provided financial/technical support to develop or improve 45 lactation spaces, with policies and practices to support mothers and families for 34 businesses. We identified key takeaway lessons that can be used to guide the development of lactation spaces and policies in work sites. Sites self-report that these work-site changes were sustainable at 6-month follow-up.
A Little Word That Means A Lot: A Reassessment of Singular They in a New Era of Gender Politics
Authors: Saguy Abigail C. , Williams Juliet A.
Published: November 2021

Singular they has emerged as a key term in contemporary gender politics, reflecting growing usage of they/them as nonbinary personal pronouns. Drawing on interviews with 54 progressive gender activists, we consider how singular they can be used to resist and redo aspects of the prevailing gender structure. We identify three distinct usages of singular they: (1) as a nonbinary personal pronoun, (2) as a universal gender-neutral pronoun, and (3) as an indefinite pronoun when a person’s self-identified gender is unknown. While previous research on singular they as a gender-inclusive language practice has focused primarily on its usage as a nonbinary personal pronoun, our findings point to the relevance for gender politics of all three usages. Our analysis offers new insight into how nonbinary they challenges dominant gender norms and practices beyond incorporating additional gender categories. Given our findings, we propose further investigation of how using gender-neutral pronouns for everyone in specific contexts can advance progressive activists’ goals. Finally, we argue that the longstanding usage of singular they as an indefinite pronoun has new importance today in affirming gender as a self-determined identity.
Numerical simulation of particle screening efficiency of large multi-layer vibrating screen based on discrete element method
Authors: Li Yujia , Zhao Peng , Mo Li , Ren Tao , Zhang Minghong
Published: November 2021

With the increasing requirements for energy conservation and environmental protection, multi-layer vibrating screens have become hot issues. Compared with single-layer vibrating screens, multi-layer vibrating screens has much better performance in terms of processing effect, treatment capacity, and environmental protection. The research on the physical parameters of the multi-layer vibrating screen is of great significance to the actual production. However, analysis and simulation studies of multi-layer vibrating screens are limited. In this paper, the screening process of wet particles on a multi-layer vibrating screen was simulated by using the discrete element method. The characteristics and application scope of the two vibration modes were analyzed. The particle penetration rate, the number of collisions, and the distribution of the particles under 23 combinations of structures and vibration parameters were investigated. The influence of different parameters on screening performance was analyzed. Several optimal combinations of frequency, amplitude and screen inclination angle under different working conditions were obtained. The screening efficiency of the balanced elliptic motion is higher than that of the linear motion. The best combination of the three parameters is 4 mm amplitude, 20 Hz frequency, and 3° inclination angle. The efficiency is higher when the particles follow a distribution of arithmetic on the screen. This study provides a reference for the efficient operation and optimal design of large multi-layer screening equipment.
Robust UKF-based filtering for tracking a maneuvering hypersonic glide vehicle
Authors: Huang Jingshuai , Zhang Hongbo , Tang Guojian , Bao Weimin
Published: November 2021

To track a non-cooperative hypersonic glide vehicle (HGV) without any precise information, an approach to the state estimation is presented based on a robust UKF-based filter (RUKFBF) in this paper. The HGV has an uncertain reentry motion because of unknown maneuvers which is a primary factor leading to degradation of tracking accuracy. Aiming at enhancing accuracy, the strong tracking algorithm (STA) is introduced to addressing the model error caused by a bank-reversal maneuver of HGV. Furthermore, the Huber technique is employed to deal with possible measurement model errors. In the RUKFBF, mutual interferences are suppressed between the STA and the Huber technique via two strategies. The one is that the calculation of the fading factor in the STA adopts an unmodified measurement noise covariance, and the other one is that two judgment criteria are proposed to limit large fading factors in the presence of measurement model errors. To simulate real tracking scenarios, the RUKFBF is tested through tracking a HGV trajectory considering a practical guidance strategy. Simulation results demonstrate the effectiveness of the RUKFBF in the presence of model errors and the observability of the estimated state.
Consolidated nuclear waste storage in Andrews, Texas: An integrated technical and policy risk analysis
Authors: Mallette Adam J. , Datta Aparajita , Krishnamoorti Ramanan
Published: November 2021

Over the last 50 years, nuclear energy has reduced US energy-related CO2 emissions by over 30 gigatons compared to if the same electricity were produced by fossil fuels such as coal and natural gas. However, many kilotons of spent nuclear fuel have accumulated at different sites across the country, and sociopolitical factors have frustrated efforts to address the challenge of nuclear waste disposal. Presently, a consolidated interim storage facility in Andrews, Texas, provides a promising temporary solution. In this paper, we compare the technical and policy risks of the project to continued storage at independent spent fuel storage installations. Our results indicate that the cost of the radiological risk is low (<$30,000) for both scenarios. However, policy and societal considerations will impact the viability of the proposed consolidated interim storage facility. The safety and suitability of this interim storage facility will be affected by when a permanent repository becomes available, whether insurance for offsite waste storage is available, and the impact of climate risks. Although a consolidated interim storage facility at Andrews can potentially serve as a safe and economically advantageous solution, we highlight why these concerns must be addressed for the successful implementation of this facility, and more broadly for the future of the US nuclear industry.
Spatial analysis of public residential housing's electricity consumption in relation to urban landscape and building characteristics: A case study in Singapore
Authors: Neo Hui Yun Rebecca , Wong Nyuk Hien , Ignatius Marcel , Yuan Chao , Xu Yong , Cao Kai
Published: November 2021

In a highly populated country like Singapore, a significant percentage of our gross annual electricity consumption stems from our domestic electricity usage in our residential houses. Analyzing and understanding factors that could influence such patterns is thus essential in order to derive effective measures to reduce usage. In this research, 16 identified variables were calculated and considered in the spatial analyses based on various buffer sizes. Both multilinear regression (MLR) and geographically weighted regression (GWR) based analyses were conducted using each residential housing's Energy Unit Intensity (EUI) as the dependent variable. The analyzed results have shown that building characteristics variables have more significant influences towards energy consumption patterns as compared to urban landscape variables. Although little difference was observed across different buffer sizes, more reliable results were obtained from a smaller buffer size of 50 m, suggesting its suitability in using these obtained values for further prediction model analysis and development. Results obtained from the GWR-based analysis have shown a significant improvement in the goodness-of-fit value compared to the MLR-based analysis, effectively indicating that GWR performs better in this context, apart from its better explanation on the contribution of these identified variables to the EUI in this case study.
Inhibitory effect of thyme oil as an antioxidant for waste cooking oil biodiesel crystallization
Authors: Uguz Gediz
Published: November 2021

The effects of thyme oil extract as an antioxidant on crystallization properties of waste cooking oil biodiesel were investigated. The inhibitory effect was determined for ASTM D7545 standard method for biodiesel added with 1000, 2000, and 3000 ppm of additives by using oxifast device and compared with the chemical antioxidant butylated hydroxytoluene (BHT). Inhibition time data were determined by converting the oxidation stability analysis results. The crystallization temperatures (Tcr) of the samples were determined by using a Differential Scanning Calorimetry (DSC) technique. Tcr values of samples with antioxidants were decreased compared to the non-antioxidant biodiesel sample (B100). The order of antioxidant power was B100<B100T1<B100T2 = B100BHT1<B100BHT2<B100T3<B100BHT3. The solid fat content (SFC %) values were determined with different antioxidant concentrations versus different times. The minimum SFC % was determined in B100T3 and B100BHT3 in 3000 ppm antioxidant concentrations in 720 min. DSC results show that the crystallization onset temperatures for B100, B100T3, and B100BHT3 were −51.83 °C, −53.59 °C, and −54.15 °C, respectively. The kinetics of crystallization was determined and k and n values were calculated. The addition of thyme oil extract as a natural antioxidant has a positive effect on biodiesel oxidative stability for all concentrations.
Nondestructive evaluation of biogenic amines in crayfish (Prokaryophyllus clarkii) by near infrared spectroscopy
Authors: Liu Yan , Wang Chao , Xia Zhenzhen , Chen Jiwang
Published: November 2021

Biogenic amines are a group of nitrogen substances and widely adopted to assess the food safety, especially for the aquatic products. In China, crayfish ( Prokaryophyllus clarkii) have become one of the most famous aquatic products and form a complete industrial value chain. To ensure the safety of the crayfish industrial chain, a rapid and nondestructive method for determining the biogenic amines of crayfish by near infrared spectroscopy coupled with chemometrics was proposed in this study. The quantitative models of histamine, tyramine, cadaverine, and putrescine were built by using the partial least squares (PLS) regression. The spectral preprocessing and the wavelength selection methods were adopted to optimize the models. For histamine, cadaverine, and putrescine in peeled or whole tails, reasonable quantitative results can be obtained by using the optimized models; the coefficient of determination (r2) are 0.88 and 0.90, 0.88 and 0.91, 0.89, and 0.84, respectively. As for tyramine in peeled or whole tails, the results are acceptable and the coefficient of determination (r2) is 0.83 and 0.74, respectively.
The accidentology of sport in France through the prism of the legitimacy theory: A first multilevel quantitative approach
Authors: Routier Guillaume , Isner Jade , Lefèvre Brice
Published: November 2021

In many so-called developed countries, participation to at least one physical activity or sport is a mass phenomenon. More, the combination of a high involvement rate and omnivorousness/voraciousness results in a very high volume of practice and lead to a significant volume of accidents. Academic studies have shown the importance of socio-demographic characteristics, such as age and sex, the mode of practice and the physical activity or sport itself in the occurrence of accidents. However, it is also necessary to take into account certain cultural dimensions of investment in sport, and more particularly the legitimate definition of risk specific to each activity. Since commitment and risk-taking are characteristic of young men, we tested the hypothesis that there are more accidents in physical activity or sports in which young men are statistically over-represented. This study evaluated this hypothesis using a sample of 29,000 reported physical activity or sports for a sample of 7,424 practitioners (national survey of the Ministry of Sports in France, people aged 15 and over). We used a multilevel cross classified logistic regression. The results show first a strong effect of the variable concerning the overrepresentation of young men in a physical activity or sport. Secondary, other results are more usual with the effect of modes of practice involved (high frequency, club and competition) and of the physical activity or sport itself (example of alpine skiing) and a single sociodemographic characteristic (the under 30 yo). Conversely, some results are more original, showing the non-effect of sex taken independently. These results provide essential information for taking into account the cultural dimension in sport-related prevention and for the management of the teams responsible for administering it.
Modeling and experimental investigation of magnetically coupling bending-torsion piezoelectric energy harvester based on vortex-induced vibration
Authors: Sui Wentao , Zhang Huirong , Yang Chongqiu , Zhang Dan , Song Rujun , Yang Xiaohui
Published: November 2021

This paper presents a magnetically coupling bending-torsion piezoelectric energy harvester based on vortex-induced vibration from low-speed wind. The theoretical model of the energy harvester was formulated and validated by wind tunnel experiments. Numerical and experimental results showed that the power output and bandwidth of the proposed harvester are improved about 180% and 230% respectively compared with the nonmagnetic coupling harvester. Furthermore, the effects of cylinder, piezoelectric layer, load resistance, and magnetic nonlinear parameters on the harvester were investigated based on the distributed parameter model. The results showed that the length of cylinder hardly affect output power, but the diameter of cylinder presented complicated influences. The width of piezoelectric beam was negatively correlated with the torsion angle. With increasing the length of piezoelectric layer, an optimal wind velocity and load resistance can be obtained for the maximum output power. With decreasing of the distance between two magnets, the resonant bandwidth, the optimal power output, and torsion angle can be enhanced, respectively. Besides, the magnetic potential energy increased owing to the magnetically coupling, which led to the improvement of onset speed for the energy harvester. This study provides a guideline on improving the performance of bending-torsion vibration piezoelectric energy harvester.
The Plantar Fascia Talar Head Correlation: A Radiographic Parameter With a Distinct Threshold to Validate Flatfoot Deformity and Its Corrective Surgery on Conventional Weightbearing Radiographs
Authors: Merian Marc , Kaim Achim
Published: November 2021

Background:

Corrective surgery for flexible flatfoot deformity (FD) remains controversial, and one of the main reasons for this is the lack of standardized radiographic measurements to define an FD. Previously published radiographic parameters to differentiate between a foot with and without an FD do not have a commonly accepted and distinct threshold.

Methods:

The plantar fascia–talar head correlation (PTC) with its defined threshold was assessed by measuring the distance between the medial border of the plantar fascia and the center of the talar head (DPT) on conventional dorsoplantar and lateral weightbearing radiographs; the authors were blinded to the clinical diagnosis of the 189 patients’ first visits. Feet were sorted into groups with and without an FD based on their clinical examination. The effect of operative corrections of FD on the PTC was retrospectively evaluated on an additional 38 patients.

Results:

The sensitivity of the PTC was 0.98 (95% CI: 0.9-1) and specificity 0.96 (95% CI: 0.92-0.98), respectively, to identify an FD, consistent with the clinical examination. Thirty-five of 38 surgeries sufficiently corrected the FD and the PTC comparable to that in subjects without an FD. Three corrections with a residual FD did not adequately correct the PTC.

Conclusion:

The PTC is a reliable radiographic parameter with a distinct threshold that is sensitive and specific for the differentiation of feet with and without an FD including feet with and without residual FD after corrective surgery. The PTC is applicable to monitor the needed intraoperative amount of correction using simulated weightbearing fluoroscopy.

Level of Evidence:

Level III, diagnostic.
Hsa_circ_0013290 Acts as Cancer-Promoting Gene in Hepatocellular Carcinoma
Authors: Luo Xi , Liu Yicun , Li Han , Cheng Tiaochun , Wu Jianjun , Chen Lin , Ju Linling , Cai Weihua , Bian Zhaolian
Published: November 2021

Background

As a new class of non-coding RNAs, circRNAs have been recently reported to be involved in the tumorigenesis and progression of human cancers. In the current study, we attempted to explore the potential function of a novel circRNA (hsa_circ_0013290) in hepatocellular carcinoma (HCC).

Methods

Relative hsa_circ_0013290 expression was analyzed by quantitative reverse transcription-polymerase chain reaction (qRT-PCR). The subcellular location of hsa_circ_0013290 was performed by RNA subcellular isolation and fluorescence in situ hybridization (FISH) assays. The effect of hsa_circ_0013290 on proliferation was detected by Cell Counting Kit-8 (CCK-8) assays. The effect of hsa_circ_0013290 on cell cycle distribution and apoptosis was detected by flow cytometry. The invasion and migration abilities of hsa_circ_0013290 were detected by transwell assays.

Results

Hsa_circ_0013290 is significantly upregulated in HCC cell lines and mainly located in cytoplasm of HCC cells. Hsa_circ_0013290 overexpression promotes cell invasion and migration and inhibits cell apoptosis. In contrast, hsa_circ_0013290 knockdown impedes cell invasion and migration and accelerates cell apoptosis. However, hsa_circ_0013290 did not affect cell proliferation.

Conclusions

Hsa_circ_0013290 is overexpressed in HCC cell lines and is mainly located in the cytoplasm of HCC cells. Hsa_circ_0013290 promotes cell invasion and migration, and inhibits cell apoptosis.
Impact of Family and Social Network on Tobacco Cessation Amongst Cancer Patients
Authors: Neumann Melissa , Murphy Neal , Seetharamu Nagashree
Published: November 2021

Continued smoking after a cancer diagnosis adversely affects outcomes, including recurrence of the primary cancer and/or the development of second primary cancers. Despite this, prevalence of smoking is high in cancer survivors and higher in survivors of tobacco-related cancers. The diagnosis of cancer provides a teachable moment, and social networks, such as family, friends, and social groups, seem to play a significant role in smoking habits of cancer patients. Interventions that involve members of patients’ social network, especially those who also smoke, might improve tobacco cessation rates. Very few studies have been conducted to evaluate and target patients’ social networks. Yet, many studies have demonstrated that cancer survivors who received higher levels of social support were less likely to be current smokers. Clinicians should be doing as much as they can to encourage smoking cessation in both patients and relevant family members. Research aimed at influencing smoking behavioral change in the entire family is needed to increase cessation intervention success rate, which can ultimately improve the health and longevity of patients as well as their family members.
Boundary and interface conditions in the relaxed micromorphic model: Exploring finite-size metastructures for elastic wave control
Authors: Rizzi Gianluca , d’Agostino Marco Valerio , Neff Patrizio , Madeo Angela
Published: November 2021

In this paper, we establish well-posed boundary and interface conditions for the relaxed micromorphic model that are able to unveil the scattering response of fully finite-size metamaterial samples. The resulting relaxed micromorphic boundary value problem is implemented in finite-element simulations describing the scattering of a square metamaterial sample whose side counts nine unit cells. The results are validated against a direct finite-element simulation encoding all the details of the underlying metamaterial’s microstructure. The relaxed micromorphic model can recover the scattering metamaterial’s behavior for a wide range of frequencies and for all possible angles of incidence, thus showing that it is suitable to describe dynamic anisotropy. Finally, thanks to the model’s computational performances, we can design a metastructure combining metamaterials and classical materials in such a way that it acts as a protection device while providing energy focusing in specific collection points. These results open important perspectives for the short-term design of sustainable structures that can control elastic waves and recover energy.
History-dependent fractional hemivariational inequality with time-delay system for a class of new frictionless quasistatic contact problems
Authors: Hao Jianwei , Wang JinRong , Han Jiangfeng
Published: November 2021

We study a new frictionless quasistatic contact problem for viscoelastic materials, in which contact conditions are described by the fractional Clarke generalized gradient of nonconvex and nonsmooth functions and a time-delay system. In addition, our constitutive relation is modeled using the fractional Kelvin–Voigt law with long memory. The existence of mild solutions for new history-dependent fractional differential hemivariational inequalities with a time-delay system are obtained by the Rothe method, properties of the Clarke generalized gradient, and a fixed-point theorem.
Impacts of High Concentration, Medium Duration Coal Mine Fire Related PM2.5 on Cancer Incidence: 5-Year Follow-Up of the Hazelwood Health Study
Authors: Yu Pei , Guo Yuming , Gao Caroline X , Dimitriadis Christina , Ikin Jillian F , Del Monaco Anthony , Brown David , Sim Malcolm R , Abramson Michael J
Published: November 2021

No studies have investigated the cancer outcomes from high level medium duration coal mine fire fine particulate matter ⩽2.5 µm in diameter (PM2.5) exposure. We included 2208 Morwell residents (exposed) and 646 Sale residents (unexposed) who participated in the Hazelwood Health Study Adult Survey. Competing risk regression models were used to evaluate relationships between coal mine fire exposure and cancer incidence, adjusting for known confounders. There were 137 cancers in the exposed and 27 in the unexposed over 14 849 person-years of follow-up. A higher risk of cancer incidence was observed for Morwell participants (HR = 1.67 [95% CI 1.05-2.67]), but no evidence to suggest associations between PM2.5 exposure and incidence of all cancers (HR = 1.02 [95% CI 0.91-1.13]), or site-specific cancers. There is no strong evidence that exposure to high concentrations of mine fire-related PM2.5 over a prolonged period could explain the higher risk in exposed population in this study.
Food Safety Attitude and Associated Factors Among Mothers of Under 5 Children, Debarq Town: Community-Based Cross-Sectional Study, 2019
Authors: Dagne Henok , Azanaw Jember , Hagos Tesfaye , Addis Kidstemariam
Published: November 2021

Background:

Food-borne diseases represent a widespread and growing public health problem, both in developed and developing countries. However, this problem has more impact on health and economy in developing countries than in developed countries but reliable data is not available.

Methods:

A cross-sectional study was done in 2019 at Debarq town, Amhara region, Northwest Ethiopia. A questionnaire prepared in English after adapted from previous studies then translated in to local language Amharic was used in order to collect the data. Data were checked manually for completeness, coded, and entered in to Epi Info version 7.1 and then exported in to SPSS version 26 statistical package for analyze. Descriptive statistics, percentage, frequency, standard deviation, and mean were analyzed. Likewise, bivariable and multivariable binary logistic regression analysis were done to know the relationship between the independent variables and attitude of food safety among mothers. The variables found having a P-value <.2 in the bivariable analysis were further analyzed in multivariable binary logistic regression. The variables with P-value <.05 were considered as significantly associated with food safety attitude of mothers.

Results:

About 423 mothers of under-5 children were involved in this study. The mean age of the participants was 39.844 ± 11.02. In this study, educational status (primary education (Adjusted Odds Ratio [AOR]: 2.66; 95% Confidence Interval [CI] [1.42-4.97]), secondary education (AOR: 2.66; 95% CI [3.35-14.05]), and diploma and above (AOR: 4.07; 95% CI [1.65-10.06])), higher income (AOR: 3.58; 95% CI [1.54-8.29]), good food safety knowledge (AOR: 3.08; 95% CI [1.51-6.242]) and good food hygiene practice (AOR: 3.97; 95% CI [2.33-6.75]) were factors associated with food safety attitude in the current study.

Conclusion:

Significant proportion of participants in the study area had poor food safety attitude. Educational status, income, food safety knowledge, and food safety practice were significantly associated with food safety attitude among mothers. Food hygiene practice, knowledge, and level of education should be increased in order to improve food safety attitudes among mothers who were responsible in food processing at household level.
Dietary Practice and Associated Factors Among Pregnant Women at Public Health Institution in Mizan-Aman Town, Southwest Ethiopia
Authors: Girma Tilahun Abel , Molla Kebede Abebaw , Ejigu Amare Genetu
Published: November 2021

Background:

A poor dietary intake of key macronutrients and micronutrients adversely affects pregnancy outcomes and neonatal health. The occurrence of dietary inadequacy during pregnancy is higher compared to any other stage of the life cycle. Therefore, this study aimed to assess dietary practice and associated factors among pregnant women.

Methods:

A facility-based cross-sectional study design was conducted among 378 pregnant women from March to May 2021 at the public health institution of Mizan-Aman town, southwest Ethiopia. A systematic random sampling technique was used to reach the study participants. The short food-frequency questionnaires and nutrition-behaviors checklist measurement were used to assess the dietary practice. Nine questions were applied to assess the dietary attitudes of the respondents. After the summation of the score, the respondent was categorized as favorable attitude if their score was > the median and unfavorable attitude if their score was ⩽ to the median of the score. The data were entered into Epi Data 3.1 and exported to Statistical Package for Social Science (SPSS) version 21 software for analysis. Variables of P-value <.25 during bivariate logistic regression analysis were considered for multivariate analysis. Finally variables with an adjusted odds ratio of P-value <.05 along with a 95% Confidence interval (CI) were declared statistically significant.

Results:

The overall magnitude of good dietary practice among pregnant women was 25.1% (95% CI: 20.9, 29.71%). In multivariate logistic regression analysis, the variables having television/radio (AOR = 4.2, 95% CI: 1.8, 10.2), household food security (AOR = 3.1, 95% CI: 1.0, 9.9), good dietary knowledge(AOR = 4.1, 95% CI: 1.98, 8.6), favorable dietary attitude (AOR = 4.34, 95% CI: 1.2, 8.7), monthly income of 1000 to 2000 Ethiopian birr (AOR = 3.7, 95% CI: 1.3,11.2) and >2000 Ethiopian birr (AOR = 7.0;95% CI: 3.3,15.4) were significantly associated with good dietary practice.

Conclusion:

The dietary practice among pregnant women was very low. The factors like having television/radio, good dietary knowledge, household food security, favorable dietary attitude, and monthly income of 1000 to 200 and greater than 2000 Ethiopian birr were significantly associated with the good dietary practice of pregnant women.
Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
Authors: Shirani Afsaneh , Dalton Scott R , Avery Eric J , Arcot Jayagopal Lakshman , Meyer Christina , Stuve Olaf , Zabad Rana
Published: November 2021

A 48-year-old Caucasian woman with history of multiple sclerosis (MS) presented with erythematous papulonodular lesions in her extremities and trunk. She was being treated with glatiramer acetate (GA) for the past 10 years and the glatiramoid, Glatopa, for 2 years prior to this presentation. A skin biopsy showed CD30+ lymphoproliferative disorder consistent with lymphomatoid papulosis (LyP). Three weeks after stopping Glatopa, her skin lesions were improved. It remains unclear whether GA’s or Glatopa’s capability to alter T-cell differentiation, may have a link with LyP. This case report is a reminder to be vigilant for skin lesions in patients with MS.
Methods for Identifying Culprit Drugs in Cutaneous Drug Eruptions: A Scoping Review
Authors: Bose Reetesh , Ogbalidet Selam , Boshra Mina , Finstad Alexandra , Marzario Barbara , Huang Christina , Fahim Simone
Published: November 2021

Background

Cutaneous drug eruptions are a significant source of morbidity, mortality, and cost to the healthcare system. Identifying the culprit drug is essential; however, despite numerous methods being published, there are no consensus guidelines.

Objectives

Conduct a scoping review to identify all published methods of culprit drug identification for cutaneous drug eruptions, compare the methods, and generate hypotheses for future causality assessment studies.

Eligibility criteria

Peer-reviewed publications involving culprit drug identification methods.

Sources of evidence

Medline, Embase, and Cochrane Central Register of Controlled Trials.

Charting methods

Registered PRISMA-ScR format protocol on Open Science Forum.

Results

In total, 109 studies and 26 reviews were included comprising 656,635 adverse drug events, most of which were cutaneous. There were 54 methods of culprit drug identification published, categorized as algorithms, probabilistic approaches, and expert judgment. Algorithms had higher sensitivity and positive predictive value, but lower specificity and negative predictive value. Probabilistic approaches had lower sensitivity and positive predictive value, but higher specificity and negative predictive value. Expert judgment was subjective, less reproducible, but the most frequently used to validate other methods. Studies suggest that greater accuracy may be achieved by specifically assessing cutaneous drug eruptions and using combinations of causality assessment categories.

Conclusions

Culprit drug identification for adverse drug reactions remains a challenge. Many methods have been published, but there are no consensus guidelines. Using causality assessment methods specifically for cutaneous drug eruptions and combining aspects of the different causality assessment categories may improve efficacy. Further studies are needed to validate this hypothesis.
Predictions of the thermo elastic deformation of dry gas seal rings in the hydrodynamic lubrication regime
Authors: Chávez Alfredo , De Santiago Oscar
Published: November 2021

Dry gas seals represent a significant advancement in turbo machinery due to their ability to handle high pressures and speeds without the use of external sealing fluids, such as oil or water, thus reducing contamination and increasing reliability. Despite their widespread use, internal working mechanisms are not fully understood to date, in particular regarding fluid film thickness prediction, which is an essential component of the seal design. The axial deflection of the rotating and stationary rings in a dry gas seal affects the development of the fluid film formed between the ring faces of the seal, influencing the performance of the seal during its operation, as well as leakage of the seal when it is at rest. The hydrodynamic and hydrostatic pressure fields of the fluid film, together with temperature gradients in the rings, induce axial deflection of these components. This in turn modifies the pressure field developed in the film. This paper focuses on establishing a methodology to couple the deformation field and the dynamic behavior of the fluid film (pressure and temperature fields) through numerical computations. Analytical relationships are employed to obtain the thermo-elastic deflection of the seal rings in the axial direction and this distortion is used in the numerical methodology to accelerate the prediction of the seal behavior. The coupled seal ring-fluid film dynamic system with 11° and 15° spiral angle is stable because the axial deflection calculated from numerical analysis produces a converging radial taper in the direction of the flow (producing a net opening force). An important result of this work is that the predicted magnitude of the axial deflection (as a result of pressure and temperature effects) under thermal and pressure loads on the stationary and rotating rings is smaller but of the same order of magnitude as the fluid film thickness.
Spatial-temporal disparities in the impact of the coronavirus disease 2019 on domestic tourism demand: A study of Emeishan National Park in Mainland China
Authors: Tan Ting , Zha Jianping , Tang Jianying , Ma Rong , Li Wenjia
Published: November 2021

The ongoing coronavirus disease 2019 pandemic, like other disasters or crises, can immensely influence visitors’ demand to visit affected destinations. The current study helps us better understand how this health crisis could affect the demand change from a micro-level perspective of small-scale tourist destinations. Based on the web search data from the Baidu Index, the present study adopts the Emeishan National Park in China as the study area and employs multiple methods to assess the spatial-temporal disparities in the impact of the coronavirus disease 2019 on domestic tourism demand. The main findings reveal that the demand changes during the observation period resemble a U-shaped curve along with the outbreak, spread, and control of the crisis, and such impacts exhibit different characteristics in the pre-event, prodromal, emergency, intermediate, and long-term recovery stages. During and after the pandemic, the short-distance market is the most vulnerable, but it presents the strongest resilience, while the medium- and long-distance markets are relatively less affected. Significant stratified heterogeneity in the tourism demand of domestic source markets also emerges before and after the crisis. Finally, some implications of promoting domestic tourism recovery in the post-pandemic era are discussed, and recommendations are made.