bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Pregnancy on the Prognosis of COVID-19 in Women Hospitalized at the National Reference Center for Patients Infected with SARS-CoV-2 in a Resource-limited Country
Authors: Kotosso Awèréou , Douaguibe Baguilane , Bawe Lidaw D. , Patassi Akouda A. , Assenouwe Sarakawabalo , Aziagbe Koffi A. , Tsevi Yaovi M. , Abaltou Bawoubadi , Zouwera Sesso , Watara Gani , Macamanzi Laroutoki , Adjoh Komi S. , Wateba Majesté I. , Djibril Awalou M.
Published: November 2022

Aim:

The aim of the study was to reduce morbidity and mortality associated with COVID-19 in pregnant women.

Background:

Since the detection of the first case of COVID-19 on March 6, 2020, in Togo, pregnant women have received special attention due to their usual vulnerability to infection.

Objective:

The objective of this study was to evaluate the influence of pregnancy on the prognosis of COVID-19 in patients hospitalized in Lomé.

Methods:

This was an analytical cross-sectional study of women of childbearing age (15-49 years) admitted between March 22, 2020, and December 31, 2021, to the Lomé Commune Regional Hospital, a national referral center for COVID-19 patients.

Results:

We registered 438 women of childbearing age, including 31 pregnant women (7.1%). Pregnant women were younger (28.8 years vs. 34.2 years, p = 0.001). Asthenia was more common in pregnant women (38.7% vs. 20.6%, p = 0.025), and SpO2 was lower (88.6% vs. 94%, p= 0.016%). Pregnancy was not associated with the occurrence of severe forms nor with prolonged hospitalization. Independent risk factors for mortality were 3rd trimester of pregnancy, mean age > 34 years, diabetes, HIV, and obesity.

Conclusion:

Most symptoms were similar to those observed in the general population. However, in addition to comorbidities, complications in the third trimester of pregnancy have worsened the prognosis for COVID-19. These results corroborate the observations made in the subregion. However, it is important to assess the effect of COVID-19 on pregnancy outcomes.
A study of staff nurses' perceptions of nursing leadership styles and work engagement levels in Saudi general hospitals
Authors:   Faculty of Nursing, King Abdulaziz University, Jeddah, Saudi Arabia, Asiri Areej Mohammed , Mahran Sabah Mahmoud , Elseesy Naglaa Abdelaziz
Published: November 2022

Leadership styles are meaningful in facing obstacles in healthcare, such as improving quality of care and performance of safety, minimizing expense, and keeping high-performing nursing staff; as a result, they can positively or negatively affect nursing work engagement, which has an impact on employee satisfaction, patient satisfaction, and organizational productivity. Thus the objective of this study is to determine the perception of the relationship between nurse managers' leadership styles and the levels of work engagement of the staff nurses in the Kingdom of Saudi Arabia. This study used a quantitative, descriptive, cross-sectional, and correlational design. A convenience sampling technique was used to select 383 staff nurses working in governmental hospitals in Saudi Arabia. The Utrecht Work Engagement Scale and the Multifactorial Leadership Questionnaire 5X short form were used to collect data. The study found that transformational leadership style (M±SD: 2.34±.946) and transactional leadership style (M±SD: 2.03±.686) had the highest mean scores from staff nurses' perceptions, while laissez-faire leadership style (M±SD: 1.4±.991) had the lowest mean score. Moreover, the highest mean score of staff nurses’ work engagement was dedication (M±SD: 4.80±1.380), and the lowest mean score for vigor (M±SD: 4.02±1.424). There was a strong statistically significant positive relationship between transformational and transactional leadership styles and staff nurses' levels of work engagement (r=0.591, r=0.517, P=0.000), respectively, while there was a negative but not statistically significant relationship between laissez-faire leadership style and staff nurses' levels of work engagement (r=-0.023 and p=0.64). Nurse managers who utilize transformational and transactional leadership approaches to empower and collaborate with staff nurses can improve organizational performance.
Factors That Affect Knowledge-Sharing Behaviors in Medical Imaging Departments in Cancer Centers: Systematic Review (Preprint)
Authors: Almashmoum Maryam , Cunningham James , Alkhaldi Ohoud , Anisworth John
Published: November 2022

BACKGROUND

Knowledge management plays a significant role in health care institutions. It consists of 4 processes: knowledge creation, knowledge capture, knowledge sharing, and knowledge application. The success of health care institutions relies on effective knowledge sharing among health care professionals, so the facilitators and barriers to knowledge sharing must be identified and understood. Medical imaging departments play a key role in cancer centers. Therefore, an understanding of the factors that affect knowledge sharing in medical imaging departments should be sought to increase patient outcomes and reduce medical errors.

OBJECTIVE

The purpose of this systematic review was to identify the facilitators and barriers that affect knowledge-sharing behaviors in medical imaging departments and identify the differences between medical imaging departments in general hospitals and cancer centers.

METHODS

We performed a systematic search in PubMed Central, EBSCOhost (CINAHL), Ovid MEDLINE, Ovid Embase, Elsevier (Scopus), ProQuest, and Clarivate (Web of Science) in December 2021. Relevant articles were identified by examining the titles and abstracts. In total, 2 reviewers independently screened the full texts of relevant papers according to the inclusion and exclusion criteria. We included qualitative, quantitative, and mixed methods studies that investigated the facilitators and barriers that affect knowledge sharing. We used the Mixed Methods Appraisal Tool to assess the quality of the included articles and narrative synthesis to report the results.

RESULTS

A total of 49 articles were selected for the full in-depth analysis, and 38 (78%) studies were included in the final review, with 1 article added from other selected databases. There were 31 facilitators and 10 barriers identified that affected knowledge-sharing practices in medical imaging departments. These facilitators were divided according to their characteristics into 3 categories: individual, departmental, and technological facilitators. The barriers that hindered knowledge sharing were divided into 4 categories: financial, administrative, technological, and geographical barriers.

CONCLUSIONS

This review highlighted the factors that influenced knowledge-sharing practices in medical imaging departments in cancer centers and general hospitals. In terms of the facilitators and barriers to knowledge sharing, this study shows that these are the same in medical imaging departments, whether in general hospitals or cancer centers. Our findings can be used as guidelines for medical imaging departments to support knowledge-sharing frameworks and enhance knowledge sharing by understanding the facilitators and barriers.
Health Economic Evaluation of Cognitive Control Training for Depression: Key Considerations (Preprint)
Authors: Nève de Mévergnies Constance , Verhaeghe Nick , Koster Ernst H W , Baeken Chris , Vander Zwalmen Yannick , Hoorelbeke Kristof
Published: November 2022

UNSTRUCTURED

Depression is a serious and burdensome psychiatric illness that contributes heavily to health expenditures. These costs are partly related to the observation that depression is often not limited to a single episode but can recur or follow a chronic pathway. In terms of risk factors, it is acknowledged that cognitive impairments play a crucial role in vulnerability to depression. Within this context, cognitive control training (CCT) has shown its effectiveness in reducing the risk for recurrence of depression. CCT is low cost intensive and can be provided as a web-based intervention, which makes it easy to disseminate. Despite increasing interest in the field, studies examining the cost-effectiveness of CCT in the context of depression are largely missing. Health economic evaluation (HEE) allows to inform decision makers with evidence-based insights about how to spend limited available (financial) resources in the most efficient way. HEE studies constitute a crucial step in the implementation of a new intervention in clinical practice. Approaching preventive measures for depression such as CCT from an HEE perspective is informative to health policy, fostering optimal use of health expenditures. The aim of this paper was to inform and guide researchers during the phase of designing HEE studies in the context of CCT for depression. A clear view of CCT’s cost-effectiveness is paramount for its clinical implementation.
IOT based Social Safety Android Application using Geolocation for Real Time Tracing
Authors: Phadatre Shubham , Kudale Raj , Ladkat Pranav , Balshetwar Tejas , Shinde Prof. Anita Vikram
Published: November 2022

Abstract: Women's security is a critical issue in today's world, and it is very crucial for every individual to be acting over such a problem. But this problem is not only limited to women but also to other citizens like old people and children. Today most of the old people and children are victim of illness and child abuse. Crime against senior citizens in the New Delhi city rose by 22% in 2021 compared to 2020 as published by National Crime Records Bureau (NCRB). According to NCRB crime against children in 2019 recorded were 1,48,185 cases, which means an average of 400 crimes were committed every day in the country. These society problems led the motivation for development of a social safety application.
PID Controllers Performance On Dual Axis Tracking With Tetrahedron Based Sensor
Authors: Melinda Melinda , Novandri Andri , Away Yuwaldi
Published: November 2022

This study compares control systems applied to a dual-axis tetrahedron-based sensor tracker. A tetrahedron-based sensor is a tracking sensor that can detect the coordinates of a light source. This study aims to determine a control system that can control sensors with high accuracy and precision and has a fast-tracking ability. Tests are carried out periodically by providing light at certain coordinates. After carrying out the testing and analysis process, it is concluded that the P controller is a better control system than the other controllers. This controller can control sensors with high accuracy and precision compared to PI, PD, and PID control systems. The P controller can also control the sensor to move towards the light coordinates with a travel time of 1.6 seconds on the X-axis and 3.1 seconds on the Y-axis, with a MAE value of 1.1 on the X-axis and 0.3 on the Y-axis. While the RSME value obtained is 1.33 on the X-axis and 0.55 on the Y-axis.
Big data in geodetic software
Authors: Tsvetkov V.Ya. , Oznamets V.V.
Published: November 2022

The authors explore the problem of big data in the view of Earth sciences and spatial information. It is noted that the matter has existed since the beginning of space research. The conclusion is that this problem is subtle and is related to the level of developing computer technology and computational models. We analyze the issues of big data occurrence and its reasons. As one of the methods for working with such volumes, cloud computing is proposed. It is proved that spatial data make up the bulk of them. It is shown that streaming information processing methods give way to this technology. The impact of big data on surveying support is researched. The conclusion is made that modern geodetic support can be considered as applied and fundamental. Applied geodetic support is aimed at solving the corresponding problems and is connected with technological supplement. For it the big data issue is important, but not as significant as for fundamental geodetic support. In that level of research it is defined as an integrated set of technologies for which the mentioned matter is relevant. Fundamental geodetic support includes measurements, comprehensive analysis and calculations and is closely related to processing and analysis of big data. As a promising way for it, quantum computing is proposed.
DESENVOLVIMENTO E APLICAÇÃO DE JOGOS LÚDICOS PARA CRIANÇAS DO ENSINO FUNDAMENTAL I SOBRE INOVAÇÃO
Authors: Largura Leandro Rafael Rabello , Neves Renata Heisler , Do Carmo Flávia Lima
Published: November 2022

Este artigo trata do desenvolvimento e aplicação de jogos lúdicos para crianças do ensino fundamental I sobre inovação e tem como finalidade expor o uso de jogos lúdicos como estratégia de educação em propriedade intelectual para crianças. Nossa pesquisa é descritiva do tipo relato de experiência e constituiu na elaboração de diferentes tipos de jogos lúdicos sobre inovação, com a ida às escolas para avaliar o aprendizado dos alunos sobre o tema desenvolvido. Com o resultado do pré-teste identificou-se que as maiorias das crianças desconhecem o assunto “Inovação” principalmente na escola pública, enquanto que na escola privada, foi possível perceber um grau de conhecimento prévio. Após a realização dos jogos e do pós-teste aplicado, foi observado a eficácia da atividade educativa, visto que as informações demostraram que a maioria dos alunos aprenderam um pouco mais sobre o assunto.
Nanomedicines for Therapy of Bladder Cancer
Authors: Song Cheeun , Jang Seung Ju , Jeon Woo Hyeok , Maeng Sejung , Tae Jong Hyun , Chang In Ho
Published: November 2022

Bladder cancer is one of most common malignant urinary tract tumor types, and transurethral resection of nonmuscle invasive bladder cancer followed by intravesical instillation of immunochemotherapy is the standard treatment approach to minimize recurrence and delay progression of bladder cancer. In general, conventional intravesical immunochemotherapy lacks selectivity for tumor tissues and the effect of drug is reduced with the excretion of urine leading to frequent administration and bladder irritation symptoms. Recently, nanomedicines which adhere to the bladder tumors for a long time, and continuously and efficiently release drug to bladder cancers may overcome all the above problems. Moreover, the advances in nanomedicine based targeted therapy have led to significant improvements in drug efficacy and precision of targeted drug delivery. This review shows the available nano-systems of targeted drug delivery to bladder cancer tissues.
Effect of the different infrared levels on some properties of sage leaves
Authors: Kayacan-Cakmakoglu Selma , Atik Ilker , Akman Perihan , Doymaz Ibrahim , Sagdıc Osman , Karasu Salih
Published: November 2022

This study aims to investigate the effect of different infrared powers (IP) (38 W, 50 W, 62 W, 74 W, and 88 W) on drying kinetics, total phenolic content (TPC) and individual phenolics, antioxidant activity (AA) and antibacterial activity, and color quality of sage leaves. IP level significantly affected (p<0.05) drying kinetics, bioactive contents, and color quality of sage leaves. Higher TPC and AA were obtained from the sample dried at 88 W. Rosmarinic acid, caffeic acid, gallic acid, and luteolin were found as major phenolic compounds, and their higher levels were obtained from the samples dried at an IP level of 88 W. All samples showed antibacterial activity on test pathogens. A higher correlation was observed between TPC, rosmarinic acid level, and antibacterial activity (P>0.80). This study suggested that sage leaves should be dried at 88 W regarding lower drying times and color changes, lower phenolic degradation, and higher antibacterial activity.
Oral Peroxisome Proliferator–Activated Receptor-α Agonist Enhances Corneal Nerve Regeneration in Patients With Type 2 Diabetes
Authors: Teo Calesta Hui Yi , Lin Molly Tzu-Yu , Lee Isabelle Xin Yu , Koh Siew-Kwan , Zhou Lei , Goh Dylan Shaoying , Choi Hyungwon , Koh Hiromi Wai Ling , Lam Amanda Yun Rui , Lim Paik Shia , Mehta Jodhbir S. , Kovalik Jean-Paul , Coffman Thomas M. , Tan Hong Chang , Liu Yu-Chi
Published: November 2022

Diabetic corneal neuropathy (DCN) is a common complication of diabetes. However, there are very limited therapeutic options. We investigated the effects of a peroxisome proliferator–activated receptor-α (PPAR-α) agonist, fenofibrate, on 30 patients (60 eyes) with type 2 diabetes. On in vivo confocal microscopy evaluation, there was significant stimulation of corneal nerve regeneration and a reduction in nerve edema after 30 days of oral fenofibrate treatment, as evidenced by significant improvement in corneal nerve fiber density (CNFD) and corneal nerve fiber width, respectively. Corneal epithelial cell morphology also significantly improved in cell circularity. Upon clinical examination, fenofibrate significantly improved patients’ neuropathic ocular surface status by increasing tear breakup time along with a reduction of corneal and conjunctival punctate keratopathy. Tear substance P (SP) concentrations significantly increased after treatment, suggesting an amelioration of ocular surface neuroinflammation. The changes in tear SP concentrations was also significantly associated with improvement in CNFD. Quantitative proteomic analysis demonstrated that fenofibrate significantly upregulated and modulated the neurotrophin signaling pathway and linolenic acid, cholesterol, and fat metabolism. Complement cascades, neutrophil reactions, and platelet activation were also significantly suppressed. Our results showed that fenofibrate could potentially be a novel treatment for patients with DCN.
No difference in implant survival between 28-mm M2a RingLoc metal-on-metal and metal-on-polyethylene total hip arthroplasty: results from the Finnish Arthroplasty Register
Authors: Palomäki Antton , Hemmilä Matias , Matilainen Markus , Eskelinen Antti , Haapakoski Jaason , Puhto Ari-Pekka , Kettunen Jukka , Pamilo Konsta , Manninen Mikko , Vasara Anna , Mäkelä Keijo T
Published: November 2022

Background and purpose: Long-term outcome of small head (28 mm) metal-on-metal (MoM) total hip arthroplasty (THA) is available mainly for Metasul devices (Sulzer Medica, Winterthur, Switzerland). Biomet MoM THA was frequently used in Finland. Therefore, we assessed long-term survivorship of the M2a 28-mm RingLoc MoM THA (Biomet, Warsaw, IN, USA) and compared it with the metal-on-polyethylene (MoP) RingLoc THA from the same manufacturer.Patients and methods: We conducted a register study based on THAs from the Finnish Arthroplasty Register performed between January 1, 2000 and December 31, 2007. 290 28-mm head M2a MoM THAs and 1,647 28-mm head MoP THAs (reference group) were included. The endpoint was revision for any reason, or revision for aseptic loosening, osteolysis, liner wear, or metallosis as one group. Kaplan–Meier survival estimates were calculated, and revision risks were assessed using a Cox multiple regression model, both with 95% confidence intervals (CI).Results: No difference was found in the 15-year Kaplan–Meier survivorship between the 28-mm head M2a RingLoc MoM THA and the reference group for any reason for revision (87.7% [82.9–92.1] and 83.3% [81.0–85.3], respectively). The adjusted hazard ratio (HR) for any reason for revision for the MoM THA group compared with the reference group was at least equal or better (0.70 [0.48–1.02]). Both groups presented similar survival for revision for aseptic loosening of the cup, osteolysis, liner wear, or metallosis, at 96.2% (92.7–98.0) and 95.4% (93.9–96.5), respectively.Interpretation: In the long-term survival there was no difference between the M2a 28-mm RingLoc MoM THA and 28-mm MoP THA. Further follow-up regimens for M2a 28-mm RingLoc THA patients may be unnecessary, but long-term metal ion and radiological data is needed before any formal suggestions.
A comparison study on patient-reported outcome between obese and non-obese patients with central lumbar spinal stenosis undergoing surgical decompression: 14,984 patients in the National Swedish Quality Registry for Spine Surgery
Authors: Hareni Niyaz , Gudlaugsson Kari , Strömqvist Fredrik , Rosengren Björn E , Karlsson Magnus K
Published: November 2022

Background and purpose: Obesity has been associated with inferior outcomes after laminectomy due to central lumbar spinal stenosis (CLSS); we evaluated whether this occurs in surgery on national bases.Patients and methods: We retrieved pre- and 1-year postoperative data from the National Swedish Quality Registry for Spine Surgery regarding patients aged ≥ 50 with laminectomy due to CLSS in 2005–2018. 4,069 patients had normal weight, 7,044 were overweight, 3,377 had class I obesity, 577 class II obesity, and 94 class III obesity (“morbid obesity”). Patient-reported outcome included satisfaction after 1 year, leg pain (Numerical Rating Scale [NRS], rating 0–10), disability (Oswestry Disability Index [ODI], rating 0–100). Complications were also retrieved.Results: 1-year postoperatively, 69% of patient of normal weight, 67% who were overweight, and 62% with obesity (classes I–III aggregated) were satisfied (p < 0.001) and 62%, 60%, and 57% in obese groups I–III, respectively (p = 0.7). NRS leg pain improved in normal-weight patients by 3.5 (95% CI 3.4–3.6), overweight by 3.2 (CI 3.1–3.2), and obese by 2.6 (CI 2.5–2.7), and 2.8 (CI 2.7–2.9), 2.5 (CI 2.2–2.7), and 2.6 (CI 2.0–3.2) in obese classes I–III, respectively. ODI improved in normal weight by 19 (CI 19–20), overweight by 17 (CI 17–18), and obese by 14 (CI 13–15), and 16 (CI 15–17), 14 (CI 13–16), 14 (CI 11–18) in obese classes I–III, respectively. 8.1% of normal weight, 7.0% of overweight, and 8.1% of obese patients suffered complications (p = 0.04) and 8.1%, 7.0%, and 17% among obese classes I–III, respectively (p < 0.01).Conclusion: Most obese patients are satisfied after laminectomy due to CLSS, even if satisfaction rate is inferior compared with normal-weight patients. The morbidly obese have more complications than patients with lower BMI.
The Concept of Restorative Justice in Handling Crimes in the Criminal Justice System
Authors: Awaliah Nasution Nurul Putri , Hamdani Fathul , Fauzia Ana
Published: November 2022

Settlement of criminal cases through restorative justice, focusing directly on perpetrators, victims, and the community in the process of resolving criminal cases, Formulation of the problem how the concept of restorative justice in criminal law reform and prospects for the formulation of restorative justice in criminal law reform, using normative research methods. Based on the results of the study, it can be concluded that the concept of restorative justice can become permanent legal politics in building the national criminal law system in the future. The draft Criminal Code has accommodated the principle of restorative justice participation as a method of resolving problems outside the court, so it is very possible if the concept of restorative justice is used as a criminal law reform in Indonesia in the future and the prospects for the formulation of restorative justice in criminal law reform have been adapted in Indonesian law by  the existence of regulations made by law enforcement, where the principle of restorative justice regulated in the internal provisions of case settlement from law enforcement and it is implemented sectoral and doesn’t use a criminal law policy theory approach, namely the renewal of criminal law through the formation of laws and restorative justice theory as a whole,  namely as the approach to the concept of restorative justice.  The response to a restorative justice settlement has received a positive appreciation from the community and law enforcement officials. It is suggested the need to accommodate the settlement of criminal cases through restorative justice against criminal acts in the Criminal Procedure Code and the Criminal Code that will come with certain conditions.  Such a process also needs to be applied at all stages of the examination, starting from the investigation, prosecution, and trial.
PATHOGENETIC ASPECTS OF THE FORMATION OF ANEMIA IN CHILDREN WITH CELIAC DISEASE
Authors:   Stavropol State Medical University, Stavropol, Stavropol Krai, Russia, Klimov L.Ya. , Zhetishev R.A. ,   Kabardino-Balkarian State University named after H.M. Berbekov (KBSU), Nalchik, Kabardino-Balkarian Republic, Russia, Ivenskaya T.A. ,   Stavropol State Medical University, Stavropol, Stavropol Krai, Russia,   Stavropol Krai Regional Specialized Clinical Infectious Diseases Hospital, Stavropol, Stavropol Krai, Russia, Kuryaninova V.A. ,   Stavropol State Medical University, Stavropol, Stavropol Krai, Russia,   Stavropol City Children's Clinical Hospital named after Professor G.K. Philippskiy, Stavropol, Stavropol Krai, Russia,   “My Medical Center,” LLC, Saint Peterburg, Russia, Dolbnya S.V. ,   Stavropol State Medical University, Stavropol, Stavropol Krai, Russia,   Stavropol Krai Regional Children's Clinical Hospital, Stavropol, Stavropol Krai, Russia,   Stavropol Krai Regional Clinical Perinatal Center No. 1, Stavropol, Stavropol Krai, Russia, Yagupova A.V. ,   Stavropol State Medical University, Stavropol, Stavropol Krai, Russia,   Stavropol City Children's Clinical Hospital named after Professor G.K. Philippskiy, Stavropol, Stavropol Krai, Russia, Kochneva L.D. ,   Stavropol State Medical University, Stavropol, Stavropol Krai, Russia,   Stavropol Krai Regional Children's Clinical Hospital, Stavropol, Stavropol Krai, Russia, Drozdova E.Yu. ,   Stavropol State Medical University, Stavropol, Stavropol Krai, Russia,   Stavropol City Children's Clinical Hospital named after Professor G.K. Philippskiy, Stavropol, Stavropol Krai, Russia, Stoyan M.V. ,   Stavropol State Medical University, Stavropol, Stavropol Krai, Russia,   Stavropol City Children's Clinical Hospital named after Professor G.K. Philippskiy, Stavropol, Stavropol Krai, Russia, Cherkasova E.A. ,   Stavropol State Medical University, Stavropol, Stavropol Krai, Russia,   Stavropol City Children's Clinical Hospital named after Professor G.K. Philippskiy, Stavropol, Stavropol Krai, Russia, Kashnikova S.N. ,   Stavropol State Medical University, Stavropol, Stavropol Krai, Russia, Dyatlova A.A. ,   Stavropol State Medical University, Stavropol, Stavropol Krai, Russia,   Russian Medical Academy for Continuous Professional Education, Moscow, Russia
Published: November 2022

Celiac disease (CD) is characterized by the formation of an anemic syndrome whose etiopathogenesis if of a multifactorial origin. The main types of anemias in children with celiac disease are iron deficiency anemia (IDA) and anemia of inflammation, also called anemia of chronic disease (ACD). This bibliographical review presents current information on the iron metabolism, morphological changes in the epithelium of the intestinal mucosa in celiac disease leading to the development of iron deficiency, pathogenesis of ACD formation in celiac disease, as well as the diagnosis of IDA and ACD in celiac disease.
THORACOSCOPY IN THE TREATMENT OF THORACOABDOMINAL DUPLICATION OF THE DIGESTIVE TRACT IN AN INFANT
Authors:   Irkutsk Oblast Regional Children's Clinical Hospital, Irkutsk, Russia, Kozlov Yu.A. ,   Irkutsk State Medical Academy of Postgraduate Education, Branch of the Russian Medical Academy for Continuous Professional Education, Irkutsk, Russia,   Irkutsk State Medical University, Irkutsk, Russia, Poloyan S.S. ,   Irkutsk Oblast Regional Children's Clinical Hospital, Irkutsk, Russia,   Irkutsk State Medical University, Irkutsk, Russia, Kovalkov K.A. ,   Kuzbass Kemerovo Oblast Regional Children's Clinical Hospital named after Yu.A. Atamanov, Kemerovo, Russia, Ochirov Ch.B. ,   Kuzbass Kemerovo Oblast Regional Children's Clinical Hospital named after Yu.A. Atamanov, Kemerovo, Russia, Kapuller V.M. ,   Hadassah - Hebrew University Medical Center, Jerusalem, Israel, Narkevich A.N. ,   Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky, Krasnoyarsk, Krasnoyarsk Krai, Russia, Cheremnov V.S. ,   Irkutsk City Ivano-Matreninskaya Children's Clinical Hospital, Irkutsk, Russia
Published: November 2022

Digestive duplications are rare anomalies that can be found anywhere in the gastrointestinal tract. The purpose of this research was to demonstrate the experience of successful treatment of a combined (thoracoabdominal) type of duplication in an infant, in which the abdominal part of the duplication penetrated the diaphragm and had an intrathoracic continuation. In a newborn female patient with an antenatal diagnosis of thoracoabdominal duplication of the digestive tract, the laparotomy and removal of the abdominal portion of the duplication were performed shortly after birth. The tubular segment located in the chest was ligated at the level of the diaphragm with the purpose of removing it in the long-term period after the abdominal procedure. At the age of 3 months, the thoracoscopy and removal of the tubular form of duplication located parallel to the normally formed esophagus were performed. The postoperative period proceeded without complications. The patient was then sent home remaining asymptomatic for 6 months following the surgical intervention. The thoracoabdominal duplication of the digestive tract is a complex surgical problem. The main goal of treatment is to completely remove the duplicated organ. The study demonstrates the possibilities of minimally invasive surgery in the treatment of this pathology.
CLINICAL CASE OF SUCCESSFUL TREATMENT OF ESOPHAGEAL PERFORATION IN A 1.5 YEARS OLD PEDIATRIC PATIENT WITH POST-BURN STENOSIS
Authors:   Siberian State Medical University (SSMU), Tomsk, Russia, Bocharov R.V. , Pogorelko V.G. ,   Siberian State Medical University (SSMU), Tomsk, Russia, Kolomiytseva M.A. ,   Siberian State Medical University (SSMU), Tomsk, Russia
Published: November 2022

Treatment of deep chemical burns of the esophagus in children remains an urgent problem. The formation of pronounced cicatricial strictures leads to a significant narrowing of the esophagus, the inability to eat, and a violation of the trophic status. The main method of treatment of victims with cicatricial narrowing is bougienage of the esophagus. A special device - bougie - is inserted either “blindly” or along a thread, or along a metal conductor string. However, when performing this manipulation, there is a high probability of traumatic injury up to rupture of the esophageal wall. In the presented clinical case observation, a 1.5 y/o pediatric patient received treatment for esophageal stricture by dilatation. After performing blind forced bougienage without anesthesia and endoscopic support, there were signs of increasing acute respiratory failure. Plain radiography of the chest organs visualized the picture of pneumohydrothorax on the right. The tactics of conservative therapy of this complication was chosen, which led to a positive outcome of the treatment. Therefore, bougienage of esophageal strictures after chemical burns can be safely performed using a guide wire under general anesthesia and endoscopic control in infants.
INTESTINAL FATTY ACID-BINDING PROTEIN AS A MARKER FOR THE SMALL INTESTINE CONDITION IN CHILDREN WITH AUTISM
Authors:   Voronezh State Medical University named after N.N. Burdenko, Voronezh, Russia, Zvyagin A.A. , Bavykina I.A. ,   Voronezh State Medical University named after N.N. Burdenko, Voronezh, Russia, Vecherkin V.A. ,   Voronezh State Medical University named after N.N. Burdenko, Voronezh, Russia, Shishkina V.V. ,   Voronezh State Medical University named after N.N. Burdenko, Voronezh, Russia
Published: November 2022

The diagnostic value of intestinal fatty acid-binding protein (I-FABP) as a potential marker for small intestinal mucosal integrity has been studied in recent years. This cytoplasmic protein in enterocytes transports fatty acids to the site of lipid synthesis in the endoplasmic reticulum from the apical membrane of the enterocyte. The purpose of the research was to evaluate the level of I-FABP in children with autism spectrum disorders (ASD) depending on the adherence to a gluten-free diet (GFD) and comped to the healthy peers. Research materials and methods: a single-center, prospective, observational, continuous, controlled study of 230 children aged 3 to 15 y/o was conducted in 2019 - 2020. Group 1 included 36 children with ASD who had been on fasting for more than 6 months: 23 (64%) boys/13 (36%) girls. 49 patients with ASD without dietary restrictions made up the Group 2: 35 (71%) boys/14 (29%) girls. The [control] Group 3 included 145 apparently healthy children: 83 (57.3%) boys/62 (42.7%) girls. The patients’ median age in Group 1 was 6.5 [4.0; 8.0] y/o, 6.0 [4.0; 7.0] y/o in G2, and 8.0 [6.0; 11.0] y/o in G3, with the differences being statistically significant (p=0.0001). I-FABP was determined in blood serum by enzyme-linked immunosorbent assay using “Human Casomorphin” and “Human I-FABP” reagent kits (ELISA Kit by “Hycult Biotech, Inc.” Netherlands, with the determination error = 3.2%, 100% method sensitivity, 85% specificity). Results: the median level of I-FABP in blood serum in children with ASD on GFD was statistically significantly (5.6 times) lower compared to children who did not comply with GFD (107.4 [92.70; 197.20] pg/ml and 601 [295.7; 715.3] pg/ml) and 5.1 times lower than the level in the control group (107.4 [92.70; 197.20] pg/ml and 543.80 [388.0; 750.0] pg/ml) (p<0.001). There were no statistically significant differences in I-FABP levels between children in the control group and patients with ASD who did not use diet therapy (p=0.369). There was no statistically significant correlation found - in all groups - between the level of I-FABP and the patients’ age. Conclusion: the obtained results confirm the hypothesis of increased intestinal permeability in children with autism, which may be pathogenetically significant for some patients with ASD, and this must be taken into account in a personalized approach to prescribing the diet therapy. The GFD for children with ASD helps reducing the damage to the small intestine if are having gluten sensitivity.
CLINICAL CASE OF A SEPTIC FORM OF YERSINIOSIS
Authors:   Pirogov Russian National Research Medical University, Moscow, Russia, Egorova N.Yu. , Molochkova O.V. ,   Pirogov Russian National Research Medical University, Moscow, Russia, Shamsheva O.V. ,   Pirogov Russian National Research Medical University, Moscow, Russia, Kompaniets Yu.V. ,   Morozov Children’s City Clinical Hospital, Moscow, Russia, Antsukh A.V. ,   Morozov Children’s City Clinical Hospital, Moscow, Russia
Published: November 2022

The role of various viral and bacterial pathogens in vascular damage and the development of vasculitis is known. Yersiniosis is one of such infectious diseases that is associated with the damage of various organs and systems. Authors report the clinical case of a septic form of yersiniosis in a 16 y/o male patient with the development of generalized vasculitis with thrombus formation and organ disturbances of microcirculation. Based on the epidemiological history (the patient has visited Nepal), clinical and laboratory examination (severe intoxication, prolonged febrile fever with chills, flushing of the face and neck, conjunctivitis, scleritis, maculopapular rash with petechial elements, increased dyspnea, tachypnea, hypoxemia as a manifestation of edematous syndrome in the lungs and the development of hydrothorax, hypotension, oliguria and azotemia as a manifestation of toxic kidney, meningism; neutrophilia with a stab shift, thrombocytopenia, increased CRP, urea, creatinine, cytolysis syndrome, hypoproteinemia, hypoalbuminemia, hypoprothrombinemia, increased D-dimer levels , a decrease in the levels of protein C and S, an increase in the level of protein in the cerebrospinal fluid against the background of reactive pleocytosis; echo signs of thrombophlebitis of the left leg, X-ray picture of edematous-interstitial changes in both lungs, bilateral hydrothorax); serological study (increase in antibody titer to Y. enterocolitica in RPHA) diagnosed with yersiniosis, septic form, complicated by septic shock, DIC, acute respiratory distress syndrome, bilateral hydrothorax, III degree respiratory failure, acute kidney injury, thrombophlebitis superficial veins of the left leg, posterior tibial vein.
GUT-LIVER AXIS IN OVERNUTRITION AND MALNUTRITION IN CHILDREN
Authors:   Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russia, Kornienko E.A.
Published: November 2022

Non-alcoholic fatty liver disease (NAFLD), which is the most common liver disease in adults, is now becoming increasingly common in children as well. It is usually associated with obesity and is considered as a hepatic manifestation of the metabolic syndrome. Studies of the intestinal microbiota (IMB) and its metabolites have confirmed the association of the development of NAFLD with intestinal dysbiosis, increased permeability of the intestinal barrier, endotoxemia, and chronic inflammation, which formed the basis of the concept of the gut-liver axis. But in recent years there has been evidence linking malnourished liver steatosis (kwashiorkor and micronutrient deficiencies) with impaired IMB. Changes in the spectrum of intestinal metabolites, the ratio of primary and secondary bile acids, an increase in the permeability of the intestinal barrier, oxidation products turned out to be similar in obesity and malnutrition, which made it possible to put forward a general strategy for the prevention and treatment of NAFLD with undernutrition and overnutrition, which is based on a combination of dietary correction and exposure on the microbiota with pro- and prebiotics.
Adaptation Finance: Risks and Opportunities for Aotearoa New Zealand
Authors:   Auckland University of Technology, Hall David
Published: November 2022

Methodology: This report was developed through the co-design process of Mōhio’s Climate Innovation Lab, a fixed-term initiative which works with stakeholders to envision financial instruments to mobilise capital for climate-aligned projects and activities. A working paper was prepared through international market scanning and a review of primary and secondary literature on climate adaptation. This working paper became the basis for a workshop with local experts and stakeholders to test the viability of potential instruments in light of Aotearoa New Zealand’s unique cultural, biophysical and regulatory context. The workshop included participants from finance services, insurance, institutional investment, academia and local and central government observers. These insights were reincorporated into this final concept paper. Mōhio would like to thank the workshop participants for their time and expertise.
White Feminism and Carceral Industries: Strange Bedfellows or Partners in Crime and Criminology?
Authors: DesLandes Ann , Longbottom Marlene , McKinnon Crystal , Porter Amanda
Published: November 2022

In this article, we examine the existing policy and academic literature on punitive responses to gender-based and family violence, focusing, in particular, on women’s police stations. Specialist women’s police stations have been a feature of policing in Argentina, Brazil, and other South American as well as Central American countries since the late 1980s. They are considered to be a phenomenon of ‘the global South’, having also been set up in some African and Asian countries including Sierra Leone and India. In this article, we critique research on women’s police stations as well as the public discourse within which women’s police stations are being proposed as a solution to domestic violence – looking at questions of research design, methodology, empiricism, ethics, and criminological claims to knowledge or ‘truth’. We reflect on the significant dangers posed by the potential transfer of women’s police stations to the Australian context, especially for sovereign Indigenous women and girls. Finally, we critique what we see as deep-seated contradictions and anomalies inherent in ‘southern theory’ and white feminist carceralism.
Tatalaksana Anestesi pada Pasien dengan Perdarahan Epidural dan Infeksi COVID-19
Authors:   Faculty of Medicine Anesthesiology and Intensive Care Universitas Pelita Harapan Tangerang Indonesia, Widiastuti Monika , Ahmad Halimi Radian ,   Faculty of Medicine Anesthesiology and Intensive Care Universitas Padjadjaran Bandung, Indonesia, Rudi Prihatno M. Mukhlis ,   Faculty of Medicine Anesthesiology and Intensive Care Universitas Jenderal Soedirman, Purwokerto Indonesia, Hamzah Hamzah ,   Faculty of Medicine Anesthesiology and Intensive Care Universitas Airlangga Surabaya Indonesia
Published: November 2022

Cedera otak traumatik (COT) masih menjadi masalah kesehatan utama di seluruh dunia. Meskipun terjadi penurunan angka kejadian COT saat pandemi COVID-19 karena mobilisasi yang dibatasi, namun karena keterbatasan akses ke fasilitas kesehatan, penanganan COT menjadi terlambat. Penanganan pasien COT dengan infeksi COVID-19 berbeda karena adanya protokol dan pertimbangan yang harus dilakukan untuk keselamatan tenaga medis dan kelancaran penanganan pasien. Laporan kasus ini mengenai laki-laki berusia 41 tahun datang dengan penurunan kesadaran pasca kecelakaan kendaraan bermotor 24 jam sebelum masuk rumah sakit (RS). Pasien merupakan rujukan dari RS lain dengan cedera kepala berat. Dari hasil Computed Tomography (CT) scan kepala didapatkan epidural hematoma (EDH) akut frontal kiri – frontal kanan parasagital yang menekan lobus frontal kiri – lobus frontal kanan parasagital dengan midline shift sejauh ± 1.35 cm. Hasil pemeriksaan screening menunjukan hasil swab PCR positif. Pasien awalnya akan dirujuk ke RS rujukan COVID-19 namun tidak berhasil mendapatkan rujukan. Perdarahan epidural merupakan kondisi yang mengancam nyawa sehingga tindakan harus segera dilakukan. Pasien menjalani operasi emergensi kraniotomi evakuasi EDH dalam anestesi umum dengan protokol COVID-19. Penanganan anestesi dengan memperhatikan COVID-19 dan implikasinya pada pasien, neuroanestesi, dengan tetap menerapkan protokol COVID-19
Manajemen Anestesi pada Kraniotomi Pengangkatan Tumor High Grade Astrocytoma pada Pasien dengan Penyakit Ginjal Kronis
Authors:   Faculty of Medicine Anesthesiology and Intensive Care Universitas Udayana Bali Indonesia, J. Sutawan IB Krisna , Pramana Suarjaya I Putu , Victorya Katipana Madyline ,   Faculty of Medicine Anesthesiology and Intensive Care Universitas Udayana Bali Indonesia
Published: November 2022

Tumor supratentorial merupakan tumor otak yang paling sering dijumpai baik itu berasal dari sel otak primer maupun metastasis dari keganasan yang lain. Selain status neurologis, riwayat penyakit penyerta juga penting untuk menjadi pertimbangan tersendiri dalam tatalaksana anestesi. Pasien laki-laki usia 60 tahun, datang dengan keluhan utama telapak tangan kanan yang gemetar disetai dengan rasa kesemutan dan berbicara pelo sejak kurang lebih satu minggu. Dari pemeriksaan fisik dan penunjang didapatkan pasien dengan gangguan ginjal yang ditegakkan sebagai penyakit ginjal kronis yang disebabkan oleh sumbatan akibat infeksi pada ginjal. Selain itu, dari pemeriksaan fisik didapatkan pemeriksaan neurologis dalam batas normal, refleks fisiologis dalam batas normal, refleks patologis tidak ada, pada pemeriksaan nervus kranialis didapatkan nervus VII dekstra supranuklear dan XII dekstra supranuklear. Dari hasil magnetic resonance imaging (MRI) didapatkan gambaran Primary Malignant Brain Tumor suspek. High grade astrocytoma. Pasien lalu dilakukan operasi pengangkatan tumor dengan anestesi umum menggunakan kombinasi propofol dan dexmedetomidine sebagai agen anestesinya, sedangkan agen diuresis yang digunakan adalah larutan NaCl 3% untuk retraktor otak. Operasi berjalan selama 3 jam, dan paska operasi dilakukan ekstubasi dan pasien dirawat di ruang perawatan intensif. Prinsip tatalaksana neuroanestesi diterapkan dan pertimbangan agen anestesi yang disesuaikan dengan kondisi pasien dengan penyakit ginjal kronis harus diperhatikan pada pasien ini. Evaluasi preoperasi yang baik, komunikasi dan koordinasi yang baik antara tim bedah dan anestesi sangat diperlukan untuk kelancaran pembedahan kraniotomi.
Manajemen Anestesi untuk Evakuasi Perdarahan Subdural Pasien Cedera Otak Traumatik dengan Gagal Ginjal Kronis
Authors:   Faculty of Medicine Anesthesiology and Intensive Care Universitas Sriwijaya Palembang Indonesia, Dewi Maharani Nurmala , Prihatno MM Rudi ,   Faculty of Medicine Anesthesiology and Intensive Care Universitas Jenderal Soedirman, Purwokerto Indonesia, Fuadi Iwan ,   Faculty of Medicine Anesthesiology and Intensive Care Universitas Padjadjaran Bandung, Indonesia, Hamzah Hamzah ,   Faculty of Medicine Anesthesiology and Intensive Care Universitas Airlangga Surabaya Indonesia
Published: November 2022

Pengelolaan anestesi pada kasus subdural hematom disertai penyakit ginjal kronis dengan riwayat hemodialisis memberikan permasalahan bagi ahli anestesi Perubahan hemodinamik perioperatif serta perubahan farmakodinamik dan farmakokinetik obat membuat manajemen perioperatif dan pemilihan regimen anestesi serta cairan harus dipertimbangkan intraoperatif terhadap efek penurunan fungsi ekskresi ginjal pada pasien penyakit gagal ginjal kronik dengan riwayat hemodialisa. Pasien laki-laki, 56 tahun dibawa ke instalasi gawat darurat mengalami penurunan kesadaran setelah kecelakaan lalu lintas sejak 1 hari yang lalu. Pasien dengan riwayat penyakit gagal ginjal kronis serta rutin hemodialisis tiap seminggu sekali. Pada pemeriksaan CT Scan kepala didapatkan hematom subdural di regio temporoparietal sinistra. Pasien preoperatif dilakukan hemodialisa tanpa menggunakan heparin. Diputuskan untuk dilakukan kraniotomi evakuasi dengan induksi anestesi dengan propofol 1 mg/kgbb, fentanyl 2 µgr /kgbb, lidokain 1 mg/kgbb dan rocuronium 0.5 mg/kgbb. Pasien diintubasi dengan ETT 7,5 dilanjutkan rumatan anestesi dengan propofol 50 µgr /kgbb/menit, fentanyl 2 µgr/kg/jam dan rocuronium 5 µgr/kg/menit. Monitoring standar elektrokardiografi, SpO2, dan arteri line. Setelah operasi pasien dirawat diruang intensif selama 3 hari. Pasien post operatif diberikan sedasi analgetik dengan dexmedetomidine 0,2- 0,7 µgr /kg/jam
Local Characterisation and Detection of Woven Fabric Texture Based on a Sparse Dictionary
Authors: Wu Ying , Wang Ren , Lou Lin , Wang Lali , Wang Jun
Published: November 2022

To achieve enhanced accuracy of fabric representation and defect detection, an innovative approach using a sparse dictionary with small patches was used for fabric texture characterisation. The effectiveness of the algorithm proposed was tested through comprehensive characterisation by studying eight weave patterns: plain, twill, weft satin, warp satin, basket, honeycomb, compound twill, and diamond twill and detecting fabric defects. Firstly, the main parameters such as dictionary size, patch size, and cardinality T were optimised, and then 40 defect-free fabric samples were characterised by the algorithm proposed. Subsequently, the impact of the weave pattern was investigated based on the representation result and texture structure. Finally, defective fabrics were detected. The algorithm proposed is an alternative simple and scalable method to characterise fabric texture and detect textile defects in a single step without extracting features or prior information.