bluuebunny/crossref_metadata_2025 huggingface dataset:
Willis Covered Stent Implantation for Treating Radiation Internal Carotid Blowout Syndrome in Nasopharyngeal Carcinoma
Authors: Nie Fangfang , Wang Wu , Yi Peiqiang , Fan Xindong , Zhang Weitian , Yang Xiaojing , Li Zhen , Li Minghua , Hu Chaosu , Guo Xiaomao , Jie Fu
Published: August 2022

Purpose: The study of Willis covered stent implantation on life-threatening hemorrhage from Radiation Internal Carotid Blowout Syndrome (RICBS) in patients with Nasopharyngeal Cancer (NPC) was evaluated in our hospital. Materials and Methods: Five NPC patients (3 male and 2 female patients) received Willis covered stent implantation from April 2011 to March 2017, in which radiation induced hemorrhage occurred in Internal Carotid Artery (ICA) was included in this study. The median age in the patient cohort was 56 (47-63). All patients were previously treated with radiotherapy (4 received IMRT and 1receivedheavy-ion RT). The median time was four years before the ICA ruptures after irradiation. The RICBS involved the C2 segment of the ICA in three patients and C3 in two patients. Results: All five patients’ ICA bleeding stopped immediately after the operation of Willis covered stent implantation. Follow-up mean time is 10 months. One patient died of suffocation (nasal hematorrhea) 2 weeks after the operation, in which the skull base is involved from recurrent lesions and associated dysphagia. One patient had rehaemorrhagia a week after the operation. One patient died of other accident 15 months after the operation. No adverse effects such as stroke and ischemia were found in all five patients during the follow-up period. Conclusion: The Willis covered stent implantation can immediately stop the bleeding caused by RICBS to save lives immediately. It is an effective and practical method to treat RICBS in NPC patients or other head and neck cancers patients, especially for the radiation-induced vascular events
Two Adults with Rhinosinusitis Fungal Infection Post COVID-19 in A Lebanese Hospital: Case Report
Authors: Hamadeh Matina , Khatoun Amena , kreidly Zouheir , Bjaiji Mohammad , Farah Assi
Published: August 2022

Coronavirus disease 2019 (COVID-19) is a newly-emerging viral illness, affecting primarily the respiratory tract, that has been linked to the occurrence of severe opportunistic fungal and bacterial infections. The incidence of fungal infection increases in patients infected with COVID-19 due to the use of corticosteroids and the accompanying uncontrolled hyperglycemia. We report two cases of acute invasive fungal rhinosinusitis (AIFR): Mucormycosis and Aspergillosis (cases 1 and 2 respectively), diagnosed radiologically and histopathologically. Both cases were treated by a combination of medical treatment and surgical debridement. The first patient improved and was discharged home, while there was a delay in the operation for the second patient who passed away. It is important to raise efforts to adjust hyperglycemia and limit the excessive systematic use of steroids during COVID pandemic to reduce fungal infections.
Kentsel Dönüşümde Sıfır Atık Yönetimi
Authors: GÜLLÜ Gültekin
Published: August 2022

Kentsel dönüşüm atıkları, kentsel dönüşüm sürecinde daha çok yapıların yıkımı sonucunda oluşmaktadır. Bu çalışmada çevrenin daha iyi korunması ve kaynakların israf edilmemesi için inşaat ve yıkıntı atıklarının sıfır atık yönetimi yaklaşımına uygun olarak nasıl daha iyi yönetilebileceği ile ilgili bir yaklaşım sergilemektir. Sıfır atık yönetimi yaklaşımına uygun olarak inşaat ve yıkıntı atığı bileşenlerinin ayrı ayrı nasıl değerlendirilebileceği anlatılmaktadır. Ayrıca sıfır atık yönetimi yaklaşımına uygun olarak yaşam döngüsü içerisinde inşaat ve yıkıntı atığı bileşenlerinin süreçleri ayrı ayrı açıklanmaktadır.
Prevalence of Depression among Adolescents in Narok County Kenya
Authors: Antipas Hamisi , Mutisya Sabina , Ntaragwe Maria
Published: August 2022

Depression is one of the most prevalent common mental disorders globally. This condition is also known to be a risk factor for other conditions such as suicidality, drug use disorders and delinquency among others. Understanding the prevalence of depression is important in designing intervention strategies. The sample size included 16 public secondary schools with 396 participants. Simple random and stratified sampling techniques were used. Data were collected using standardized questionnaire for depression, the PHQ 9. Quantitative data was analyzed using descriptive statistics. The results showed that across all the different types of schools, most of the students had a low levels of depression. The highest number of students with low or moderate levels of depression were in mixed boarding schools followed by mixed day secondary schools. The study recommends provision of resources to help strengthen the school guidance and counseling departments. Strengthening the relationships between parents, learning institutions and adolescents through regular engagement
Evaluation of Factors Affecting Road Maintenance in Kenyan Counties Using the Ordinal Priority Approach
Authors: Bouraima Mouhamed Bayane , Qiu Yanjun , Kiprotich Kiptum Clement , Maraka Ndiema Kevin
Published: August 2022

Improving Kenya's complete road network has been used to alleviate poverty and achieve the Vision 2030 goals. Roads enhance all areas of social development, including demand for and access to information, health, and education, in addition to poverty alleviation. However, the majority of Kenyan highways are plagued by a variety of maintenance concerns. This study aims to rank counties according to critical severity based on factors affecting road maintenance using an Ordinal Priority Approach (OPA). Five challenges that could have an impact on road maintenance were looked at from the views of three decision-makers. The results of the study show that road materials are the least challenging aspect affecting road maintenance performance, while procurement practices are the most problematic. The studies also revealed that Nairobi County is most affected by these factors, whereas Nakuru County is least affected. In light of the findings, recommendations were made to assist both the government and the road sectors in dealing with these difficulties.
 
Received: 14 June 2022 | Revised: 26 July 2022 | Accepted: 16 August 2022
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
An MCGDM Technique for Weighted Average Interaction Aggregation Operator Under Interval-Valued Intuitionistic Fuzzy Hypersoft Set Environment
Authors: Zulqarnain Rana Muhammad , Siddique Imran
Published: August 2022

The intuitionistic fuzzy hypersoft set (IFHSS) is the most generalized form ofthe intuitionistic fuzzy soft set usedto resolve ambiguous and elusive data in the decision-making (DM) process, considering the parameters’ multi-sub-attributes. Aggregation operators (AOs) execute a dynamic role in assessing the two prospect sequences and eliminating anxieties from this perception. This paper prolongs the IFHSS to interval-valued IFHSS (IVIFHSS), which proficiently contracts with hesitant and unclear data. It is the most potent technique for incorporating insecure data into DM. The core impartial of this investigation is to develop the algebraic operational laws for IVIFHSS. Furthermore, using the interaction operational law, an interaction AO for IVIFHSS has been presented, such as interval-valued intuitionistic fuzzy hypersoft interactive weighted average (IVIFHSIWA) with its essential properties. Multi-criteria group decision-making (MCGDM) technique is vigorous for material selection (MS). However, conventional methods of MCGDM regularly provide inconsistent results. Based on the expected AOs, industrial enterprises propose a robust MCGDM MS method to meet this shortfall. The real-world application of the planned MCGDM method for cryogenic storing vessel MS is presented. The implication is that the designed model is more efficient and consistent in handling information based on IVIFHSS.
 
Received: 6 July 2022 | Revised: 9 August 2022 | Accepted: 16 August 2022
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
 
Data Availability Statement
Data sharing is not applicable to this article as no new data were created or analyzed in this study.
Teacher participatory decision-making in schools: A pre-requisite for democratic governance in Ghanaian second cycle educational institutions
Authors: Aboagye Gabriel Kwesi , Ahmed Hassana
Published: August 2022

Participatory decision-making in schools has been identified as a key tool for improving teachers* professional development. However, not much has been done in terms of scientific research to find out the nature, level and areas of teacher participation in making school decisions. Therefore, this study sought to establish the areas and ways of involving Senior High School teachers in decision-making in schools in the Mampong Municipality. The descriptive survey design was adopted for the study. The purposive and stratified sampling techniques were adopted to select the participants for the study. Questionnaires were used to collect data from 252 randomly selected professional teachers. It was observed from the study that teachers were always involved in curriculum and instructional activities and occasionally engaged in school operational activities and decisions that promoted school-community relationship. However, teachers were never involved in decision making on student admission and placement, staffing and financial matters. Teachers were involved in school decision-making through delegation, school meeting, school Board of Governors, and school committee systems. It is, therefore, recommended that the heads of schools should decentralise decision-making in their schools to allow greater teachers’ involvement in decision-making.
A Cross - Sectional Study on Menstrual Hygiene Knowledge and Practices among Adolescent Girls in Tribal Population in South India
Authors: Ramya S , Murugan M Durai , Dhanalakshmi S , Ganapathi K Chellavel , Gurukartick J
Published: August 2022

Background: World health Organisation defines adolescents as young people between 10 and 19 years of age. Around 16% of world’s population are adolescents. Transition period from childhood to adult life is termed as adolescents. It is an important and a very sensitive period in the human life cycle. Many developments like physical, mental and social development occur in this adolescent period. Knowledge about menstruation and its hygiene among adolescent girls is grossly inadequate. As a result, they suffer intense mental stress due to lack of proper guidance and support regarding proper menstrual hygiene practices. Methodology: The community-based study was conducted in Valavanthi Primary Health Centre, Salem, Tamil Nadu, India. The sample size was attained by multi-stage sampling. By simple random sampling, Salem District was chosen. The respective block, primary health center and sub-centers were chosen by lottery method. Results: 73.5% girls had good knowledge about menstruation. 96.3% girls knew about the sanitary material ideally used during menstruation. 42.3% knew about the frequency of changing pad per day as 4-6 times and 98.5% girls had good knowledge about disposal of pads. 54 % of the study participants had good menstrual hygiene practices. Menstrual hygiene practices were good in adolescent girls who lived in joint families. Conclusion & recommendations: Educational interventions can bring many changes for less discussed topics like menstruation. By social marketing (making low-cost sanitary pads available), better hygienic practices can be adopted. In the school curriculum, safe hygiene and sanitary practices should be included and better communication between adolescent girls and their teachers, mother. Adolescent girls to be encouraged to attend awareness program regularly conducted at Primary Health Centre and adolescent clinics.
Privatização da Eletrobrás e suas Inconstitucionalidades
Authors: Bercovici Gilberto
Published: August 2022

O presente texto trata da privatização da Eletrobrás e das várias inconstitucionalidades presentes na lei que autorizou a alienação do controle da empresa estatal. O artigo inicia analisando o papel da Eletrobrás no Regime Constitucional da Energia Elétrica. Com a aprovação da Lei nº 14.182/2021, são introduzidas alterações nas concessões da Eletrobrás que irão afetar as tarifas de energia elétrica. A lei propõe também a instituição de uma nova empresa estatal para manter a Eletronuclear e Itaipu Binacional sob controle da União. O modelo de privatização da Eletrobrás e suas inconstitucionalidades são detalhados e o artigo destaca os impactos negativos da privatização da Eletrobrás na gestão dos recursos hídricos brasileiros, finalizando com um panorama da atual destruição do Regime Constitucional da Energia Elétrica no Brasil.
The Effects of LEDs with different CCT values on growth characteristics of Triticum aestivum L. (wheat) and Hordeum vulgare L. (barley)
Authors: ŞAHİN Mustafa , KARAGÖZ KÜÇÜK Zehra , ELVEREN Müjgan , OSMA Etem , AKALTUN Yunus
Published: August 2022

Light Emitting Diode (LED)s are used extensively in almost everywhere in our daily life and they have different color temperatures such as Correlated Color Temperature (CCT) which is represented by ˚K (Kelvin). In this study, wheat (Triticum aestivum L.) and barley (Hordeum vulgare L.) were cultivated in laboratory environment under LED with different CCT values (2000, 3000, and 6000˚K). After cultivation, plant height and weight values, the quantity of chlorophyll and carotene, the amount of leakage of electrolyte and element absorption capacity from the soil, POX (Peroxidase) and SOD (Superoxide Dismutase) enzyme activities of cultivated plants were determined. Results were evaluated on Statistical Package for the Social Sciences Program (SPSS 22) and significant differences were obtained on plants which were grown at different color temperatures of light. It was concluded that measurements from plants which were grown under LED light with cold color temperatures (6000˚K) were more consistent than those of plants grown under other lights with different temperatures. It has been deduced that cold color temperatures are closer to the optimum light values required for a plant to grow faster.
Resveratrolün Metotreksat Uygulanan Ratlarda Total Oksidan-Antioksidan Durumuna ve DNA Hasarına Etkisi
Authors: VADİ Mehmet , COMBA Bahat
Published: August 2022

Bu çalışmada resveratrolün (RES) metotreksat (MTX) uygulanan ratlarda lökosit yüzdelerine, total oksidan (TOS)-antioksidan durumuna (TAS) ve DNA hasarına (8-OHdG) etkisi araştırıldı. Çalışmada kullanılan ratlar rastgele her biri 10 rattan oluşan 4 gruba ayrıldı. Gruplar, kontrol grubu, MTX grubu (20 mg/kg i.p., haftada 1 kez, iki hafta), RES grubu (40 mg/kg/gün oral, 14 gün) MTX+RES grubu (20 mg/kg i.p, haftada 1 kez, iki hafta ve 40 mg/kg/gün oral, 14 gün) olarak oluşturuldu. Deneme sonunda ratların kalplerinden kan örnekleri alındı, lökosit (nötrofil, eozinofil, bazofil, lenfosit, monosit) yüzdelerine klasik yöntemlerle, TOS, TAS, değerlerine kolorimetrik kitlerle, 8-OHdG seviyesine ELISA kiti ile bakıldı. MTX ve MTX+RES gruplarındaki nötrofil (p≤0.05) ve monosit (p≤0.01) yüzdeleri kontrol ve RES grubuna göre istatistiksel önemde daha düşük olduğu belirlendi. Ayrıca, MTX grubundaki, TOS ve OSI seviyelerinde anlamlı bir artış (p
Hydroxyl airglow observations for investigating atmospheric dynamics: results and challenges
Authors: Wüst Sabine , Bittner Michael , Espy Patrick J. , French W. John R. , Mulligan Frank J.
Published: August 2022

Abstract. Measurements of hydroxyl (OH*) airglow intensity are a straightforward and cost-efficient method which allows information to be derived about the climate and dynamics of the upper mesosphere / lower thermosphere (UMLT) on different spatiotemporal scales during darkness. Today, instrument components can be bought “off-the-shelf” and developments in detector technology allows operation without cooling or at least without liquid nitrogen cooling, which is difficult to automate. This makes instruments compact and suitable for automated operation. Here, we provide an overview of the scientific results regarding atmospheric dynamics and relying on long-term ground-based OH*-airglow measurements or airglow measurements using a network of ground-based instruments. It includes further results from global or nearly-global satellite-based OH*-airglow measurements. Additionally, the results from the very few available airborne case studies using OH*-airglow instruments are summarised. Scientific and technical challenges for the next few years are described.
Local moisture recycling across the globe
Authors: Theeuwen Jolanda , Staal Arie , Tuinenburg Obbe , Hamelers Bert , Dekker Stefan
Published: August 2022

Abstract. Changes in evaporation over land affect terrestrial precipitation via atmospheric moisture recycling and consequently freshwater availability. Although global moisture recycling at regional and continental scales are relatively well understood, the patterns and drivers of local moisture recycling remain unknown. For the first time, we calculate the local moisture recycling ratio (LMR), defined as the fraction of evaporated moisture that rains out within approximately 50 km from its source, and identify its drivers over land globally. We derive seasonal and annual LMR from multi-year (2008–2017) monthly averaged atmospheric moisture connections at a scale of 0.5° obtained from a Lagrangian atmospheric moisture tracking model. We find that, annually, on average 1.6 % of evaporated moisture returns as rainfall locally, but with large temporal and spatial variability, where LMR peaks in summer and over wet and mountainous regions. We identify wetness, orography, latitude, and convective available potential energy as drivers of LMR, indicating a crucial role for convection. Our results can be used to study impacts of evaporation changes on local precipitation, with widespread implications for, for example, regreening and water management.
QUADICA: water QUAlity, DIscharge and Catchment Attributes for large-sample studies in Germany
Authors: Ebeling Pia , Kumar Rohini , Lutz Stefanie R. , Nguyen Tam , Sarrazin Fanny , Weber Michael , Büttner Olaf , Attinger Sabine , Musolff Andreas
Published: August 2022

Abstract. Environmental data are the key to defining and addressing
water quality and quantity challenges at the catchment scale. Here, we present
the first large-sample water quality data set for 1386 German catchments
covering a large range of hydroclimatic, topographic, geologic, land use, and
anthropogenic settings. QUADICA (water QUAlity, DIscharge and Catchment
Attributes for large-sample studies in Germany) combines water quality with
water quantity data, meteorological and nutrient forcing data, and catchment
attributes. The data set comprises time series of riverine macronutrient
concentrations (species of nitrogen, phosphorus, and organic carbon) and
diffuse nitrogen forcing data (nitrogen surplus,
atmospheric deposition, and fixation) at the catchment scale. Time series are generally aggregated
to an annual basis; however, for 140 stations with long-term water quality
and quantity data (more than 20 years), we additionally present monthly
median discharge and nutrient concentrations, flow-normalized concentrations,
and corresponding mean fluxes as outputs from Weighted Regressions on Time,
Discharge, and Season (WRTDS). The catchment attributes include catchment
nutrient inputs from point and diffuse sources and characteristics from
topography, climate, land cover, lithology, and soils. This comprehensive,
freely available data collection with a large spatial and temporal coverage
can facilitate large-sample data-driven water quality assessments at the
catchment scale as well as mechanistic modeling studies. QUADICA is
available at https://doi.org/10.4211/hs.0ec5f43e43c349ff818a8d57699c0fe1 (Ebeling et al., 2022b) and https://doi.org/10.4211/hs.88254bd930d1466c85992a7dea6947a4 (Ebeling et al., 2022a).
The CoralHydro2k Database: a global, actively curated compilation of coral δ18O and Sr / Ca proxy records of tropical ocean hydrology and temperature for the Common Era
Authors: Walter Rachel M. , Sayani Hussein R. , Felis Thomas , Cobb Kim M. , Abram Nerilie J. , Arzey Ariella K. , Atwood Alyssa R. , Brenner Logan D. , Dassié Émilie P. , DeLong Kristine L. , Ellis Bethany , Fischer Matthew J. , Goodkin Nathalie F. , Hargreaves Jessica A. , Kilbourne K. Halimeda , Krawczyk Hedwig , McKay Nicholas P. , Murty Sujata A. , Ramos Riovie D. , Reed Emma V. , Samanta Dhrubajyoti , Sanchez Sara C. , Zinke Jens ,   the PAGES CoralHydro2k Project Members
Published: August 2022

Abstract. The response of the hydrological cycle to anthropogenic climate change, especially across the tropical oceans, remains poorly understood due to the scarcity of long instrumental temperature and hydrological records. Massive shallow-water corals are ideally suited to reconstructing past oceanic variability as they are widely distributed across the tropics, rapidly deposit calcium carbonate skeletons that continuously record ambient environmental conditions, and can be sampled at monthly to annual resolution. Most coral-based reconstructions utilize stable oxygen isotope composition (δ18O) that tracks the combined change in sea surface temperature (SST) and the oxygen isotopic composition of seawater (δ18Osw), a measure of hydrologic variability. Increasingly, coral δ18O time series are paired with time series of strontium-to-calcium ratios (Sr / Ca), a proxy for SST, from the same coral to quantify temperature and δ18Osw variability through time. To increase the utility of such reconstructions, we present the CoralHydro2k database: a compilation of published, peer-reviewed coral Sr / Ca and δ18O records from the Common Era. The database contains 54 paired Sr / Ca-δ18O records and 125 unpaired Sr / Ca or δ18O records, with 88 % of these records providing data coverage from 1800 CE to present. A quality-controlled set of metadata with standardized vocabulary and units accompanies each record, informing the use of the database. The CoralHydro2k database tracks large-scale temperature and hydrological variability. As such, it is well-suited for investigations of past climate variability, comparisons with climate model simulations including isotope-enabled models – and application in paleo-data assimilation projects.The CoralHydro2k database will be available on the NOAA National Center for Environmental Information’s Paleoclimate data service with serializations in MATLAB, R, Python, and LiPD.
Using Sentinel-1 radar amplitude time series to constrain the timings of individual landslides: a step towards understanding the controls on monsoon-triggered landsliding
Authors: Burrows Katy , Marc Odin , Remy Dominique
Published: August 2022

Abstract. Heavy-rainfall events in mountainous areas trigger destructive landslides, which pose a risk to people and infrastructure and significantly affect the landscape.
Landslide locations are commonly mapped using optical satellite imagery, but in some regions their timings are often poorly constrained due to persistent cloud cover. Physical and empirical models that provide insights into the processes behind the triggered landsliding require information on both the spatial extent and the timing of landslides. Here we demonstrate that Sentinel-1 synthetic aperture radar amplitude time series can be used to constrain landslide timing to within a few days and present four techniques to accomplish this based on time series of (i) the difference in amplitude between the landslide and its surroundings, (ii) the spatial variability in amplitude between pixels within the landslide, and (iii) geometric shadows and (iv) geometric bright spots cast within the landslide. We test these techniques on three inventories of landslides of known timing, covering various settings and triggers, and demonstrate that a method combining them allows 20 %–30 % of landslides to be timed with an accuracy of 80 %. Application of this method could provide an insight into landslide timings throughout
events such as the Indian summer monsoon, which triggers large numbers of landslides every year and has until now been limited to annual-scale analysis.
Spatial patterns of snow distribution in the sub-Arctic
Authors: Bennett Katrina E. , Miller Greta , Busey Robert , Chen Min , Lathrop Emma R. , Dann Julian B. , Nutt Mara , Crumley Ryan , Dillard Shannon L. , Dafflon Baptiste , Kumar Jitendra , Bolton W. Robert , Wilson Cathy J. , Iversen Colleen M. , Wullschleger Stan D.
Published: August 2022

Abstract. The spatial distribution of snow plays a vital role in sub-Arctic and Arctic climate, hydrology, and ecology due to its fundamental influence on the water balance, thermal regimes, vegetation, and carbon flux. However, the spatial distribution of snow is not well understood, and therefore, it is not well modeled, which can lead to substantial uncertainties in snow cover representations. To capture key hydro-ecological controls on snow spatial distribution, we carried out intensive field studies over multiple years for two small (2017–2019; ∼ 2.5 km2) sub-Arctic study sites located on the Seward Peninsula of Alaska. Using an intensive suite of field observations (> 22 000 data points), we developed simple models of the spatial distribution of snow water equivalent (SWE) using factors such as topographic characteristics, vegetation characteristics based on greenness (normalized different vegetation index, NDVI), and a simple metric for approximating winds. The most successful model was random forest, using both study sites and all years, which was able to accurately capture the complexity and variability of snow characteristics across the sites. Approximately 86 % of the SWE distribution could be accounted for, on average, by the random forest model at the study sites. Factors that impacted year-to-year snow distribution included NDVI, elevation, and a metric to represent coarse microtopography (topographic position index, TPI), while slope, wind, and fine microtopography factors were less important. The characterization of the SWE spatial distribution patterns will be used to validate and improve snow distribution modeling in the Department of Energy's Earth system model and for improved understanding of hydrology, topography, and vegetation dynamics in the sub-Arctic and Arctic regions of the globe.
„Legal regulations on utilization of the Piska Forest over the centuries”
Authors: GIŻEJEWSKI GRACJAN
Published: August 2022

Na przestrzeni lat Puszcza Piska nie pozostawała zupełnie bezludna i bezużyteczna. Ryby w licznych jeziorach, zwierzyna, pszczoły przyciągały nowych osadników. Przywilej na wolne rybołóstwo, myślistwo i bartnictwo osadzie przed krzyżackim zamkiem Johannisburg (Pisz) został nadany przez komtura bałgijskiego i wójta natangijskiego Ulricha Frickego 10 listopada 1367 roku. W niniejszej pracy scharakteryzowane zostały pozostałe regulacje prawne odnoszące się do wymienionych w tym przywileju form eksploatacji Puszczy Piskiej do 1945 roku. Ponadto zawiera ona opis konsekwencji wprowadzanych regulacji na życie mieszkańców tego kompleksu leśnego, oraz informacje m.in. o sprzętach używanych podczas połowów, administracji rybackiej i leśnej, czy dodatkowych obowiązkach mieszkańców dziczy podczas polowań.
Clinic and Radiographic Evaluation of Cemento-osseous Dysplasia: Case Series
Authors: BAĞCI Nuray , ÜÇOK Özlem , PEKER İlkay
Published: August 2022

Aim: Cemento-osseous dysplasia (COD) is usually asymptomatic and slowly progressive benign fibro-osseous lesion characterized by the replacement of normal bone with fibrous tissue. The aim of this presentation is to evaluate the clinical and radiographical findings of six COD cases that were detected incidentally during radiographic examination.

Case Report: Six female patients who four (%66) of them with different dental complaints and two (%33) of them for routine control examination of the previously diagnosed COD with a mean age of 38 applied to our clinic. It was learned that the patients did not have any systemic disorders in their medical anamnesis. There is not any finding on extraoral examination. In intraoral examination, teeth associated with COD lesions were vital as a result of the electric pulp test, and there is no other finding related to the lesion. In the radiography examination, different sizes radiolucent, mixed, and radiopaque lesions were detected in the mandible on control panoramic radiographs. The lesions were examined in detail with cone-beam computed tomography. Local thinning and resorption were observed in the buccal and lingual cortical bone in the relevant region. Histopathological examination revealed that the lesions were definitively diagnosed as SOD in four patients. Based on clinical, radiographic, and histopathological examinations, three (%50) of the lesions were diagnosed as periapical COD and the others (%50) were diagnosed with fluoride COD. All patients were followed up periodically for six months.

Conclusion: The findings of this case series showed that all lesions examined were clinically asymptomatic and mixed on radiography. Due to insufficient vascular support of the bone in the COD area, there is a risk of infection and osteomyelitis may occur. Therefore, dentists should be aware of the clinical and radiographic features of COD in clinical practice and follow the patients periodically.
Investigation of the Effect of Different Content of Mouthwashes on Rezin CAD / CAM Blocks
Authors: ERSÖZ Bilge , AYDIN Numan , KARAOĞLANOĞLU Serpil
Published: August 2022

Aim: Using of mouthwashes has become more popular recently as a result of the studies on reducing the transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The aim of this study is to examine the effect of different content mouthwashes on the color changes.

Methods: Two different resin-based CAD/CAM materials (Vita Enamic and Brilliant Crios)

were used in the study (n=32). 64 samples were prepared by taking 2 × 7 × 12 mm sized sections from CAD/CAM blocks (n=32). After the samples were kept in artificial saliva at 37° C for 24 hours, initial color measurements were made with a spectrophotometer device (VITA Easy shade V, Germany). Then the samples were kept in 3 different mouthwashes containing Cetylpyridinium chloride (Oral-B), Povidone iodine (Batiqon) and Chlorhexidine (Kloroben) twice a day for 1 minute (n=8). Color measurement of the samples was repeated on the 7th, 14th and 30th days. Color change values (ΔE00) were evaluated by one-way analysis of variance (ANOVA) and Tukey test (p0.05).

Conclusion: At the end of the 30th day, color change was observed below the noticeable threshold value (ΔE00>0.8) in the hybrid ceramic CAD/CAM block samples (Vita Enamic) . In composite-reinforced CAD/CAM samples (Brilliant Crios), only Povidone-iodine-containing mouthwash produced color change above the noticeable threshold value (ΔE00>0.8), while Chlorhexidine and Cetylpyridinium chloride did not produce a noticeable change.
VIOLÊNCIA OBSTÉTRICA: UMA PRÁTICA AINDA VIVENCIADA NO PROCESSO DE PARTURIÇÃO?
Authors: Dalla Costa Lediana , Dias da Silva Rafaela , Roll Jadieli Simoni , Gonçalves Trevisan Marcela , Tuani Teixeira Géssica , Cavalheiri Jolana Cristina , Rodrigues Perondi Alessandro
Published: August 2022

Objetivo: identificar a prática da violência obstétrica vivenciada por puérperas no processo da parturição. Método: trata-se de um estudo quantitativo, exploratório-descritivo, realizada nas Unidades de Atenção Primária à Saúde de um município do Sudoeste Paranaense. A coleta de dados ocorreu entre os meses de maio a julho de 2019 por meio de questionário fechado, a amostragem foi por conveniência. O instrumento foi aplicado para puérperas com 45 dias pós-parto durante visita domiciliar, os dados foram submetidos à análise estatística descritiva através do programa Statistical Package for the Social Sciences versão 25.0. Resultados: a amostra comtemplou 157 puérperas. Observou-se que 52,9% realizaram cesariana, visto que a sua autonomia não foi preservada pois preferiam o parto normal com 74,5%. Acerca dos atos de violência obstétrica, identificou-se em maior predomínio o corte do cordão umbilical (81,5%), contato com bebê adiado (64,2%) e toques vaginais (41,4%). Conclusão: conclui-se que ainda a atos violentos nos atendimentos realizados na assistência as parturientes. Desta forma, vale salientar a importância do empoderamento feminino e a adesão as boas práticas obstétricas.
Auto-Rotating Perceptrons
Authors: Saromo Daniel , Villota Elizabeth , Villanueva Edwin
Published: August 2022

This paper proposes an improved design of the perceptron unit to mitigate the vanishing gradient problem. This nuisance appears when training deep multilayer perceptron networks with bounded activation functions. The new neuron design, named auto-rotating perceptron (ARP), has a mechanism to ensure that the node always operates in the dynamic region of the activation function, by avoiding saturation of the perceptron. The proposed method does not change the inference structure learned at each neuron. We test the effect of using ARP units in some network architectures which use the sigmoid activation function. The results support our hypothesis that neural networks with ARP units can achieve better learning performance than equivalent models with classic perceptrons.
Building Bridges: Implementing Redundancy Analysis by means of a Neural Network
Authors: Yanez Fernando
Published: August 2022

When analyzing data, there are situations where it is convenient to divide the analyzed variables into two subsets: a X block, of range p, that plays an independent or predictor role and a Y block, of range q, whose role is dependent, each of them containing the measurements of n individuals. However, knowing a priori which one is independent and which one is dependent is not trivial. The Redundancy Analysis was developed by van den Wollenberg (1977) as a particular case of CCA (Hotelling, 1936). Given two standarized data sets X (orthogonalizable) and Y, it consists in determining a set of orthonormal redundant components wi (i = 1, ..., min(p,q)) such that the squared correlation of each of the redundant variables Xwi with all the Y variates (Eq. 1) is maximized subject to unitary variance of the redundant variable. Thus, the Redundancy Index (RI) of X over Y, proposed by Stewart and Love (1968), is maximized (Eq. 2). Such index is an asymmetrical measurement for the amount of explanation one set has over the other. By comparing Rx and Ry, it can be determined which set of variables is explanatory and which one is the response.
Green synthesis and Characterization of Zinc Nanoparticles using Herbal plant Extracts with their Influence on some Bacterial Infection
Authors: Kadhem Salman Sumod Abdul , M. Taki Malaa , J. Hadi Suhad , Mansour. Jasim Adnan
Published: August 2022

The nanoparticles of ZnO biosynthesis have distinctive features. many researchers have noted it cute to research in diverse research disciplines due to modern medical applications. different NPS have been estimated for their potential usage in which zinc oxide (ZnO) nps have confirmed to be a viable replacement for treating environmental pollutants, due to their excellent capacity to absorbed rays of UV. The purchase seeds of Trigonella foenum-graecum, clove buds, and leaves of the Salvia officinalis plant from the local market and extracted by hot plate methods. the purpose of the current study was the green synthesis of ZnO nanoparticles (NPS) from the different above extracts followed by a comprehensive characterization and assessment of their biological potential. no-NPS synthesized as such was subjected to characterization employment standard techniques such as particle size and tem. highly stable crystalline NPS with sizes between 32.6 and 142.7 nm were obtained from different plants. These Nps revealed a wide range of biological applications showing antioxidant, moderate α-amylase inhibitors, antibacterial and cytotoxic powers. in addition to the percentage of s. epidermidis and k. pneumonia isolated from human and children was recorded mean (40 and 60.4 %) respectively. The highest antibacterial activity (17±0.10 mm and 18±0.09) was shown by seed salvia Officinalis-mediated ZnO NPS against k and s. epidermidis respectively. on the other aspect the result obtained from using silymarin and the mediated zinc nanoparticles showed limited zone inhibition (15 ± 0.09, 15 ± 0.15, and 8 ± 0.02, 8 ± 0.02) respectively. Among all of the NPS synthesized and used, the effect of seed extract-mediated NPS was found to be most promising for future applications.
Estimation of Nine Organic Volatile Impurities in Bulk Dapagliflozin propandiol hydrate and Dosage forms from different sources using a new developed HS-GC-FID method
Authors: Ismail Ali , Haroun Mohammad , Alahmad Youssef
Published: August 2022

As a part of impurity profiling, we aimed in this work to determine the content of organic volatile impurities (OVIs), commonly known as residual solvents (RSs), in different sources of dapagliflozin propandiol monohydrate as raw materials and marketed film-coated tablets. For that, a novel HS-GC-FID method has been developed and validated for determination of methanol, ethanol, ether, acetonitrile, dichloromethane, n-hexane, ethyl acetate, tetrahydrofuran and toluene. Dimethyl sulfoxide DMSO was used us diluent. The separation was achieved on Agilent DB-624 (30m, 0.530mm, 3.0µm) column and nitrogen as carrier gas with a total run time of 20 minutes. Solvents peaks indicate high resolution. Correlation factor R2 was estimated for each solvent and values ranged from 0.9990 to 0.9995. Estimation of limit of detection of these nine solvents showed that developed method was more sensitive than published method. The percentage recoveries calculated and the values ranged from 100.2% to 111.54%. The methods has been found to be simple, very sensitive, rugged, reliable and reproducible for the quantitation of these solvents in different sample of dapagliflozin raw materials and marketed tablets. Ethanol (class 3) and n-hexane (class 2) were detected in unacceptable level in some marketed samples.
Giant gastric trichobezoar: Case report
Authors:   Departament of Surgery, University Hospital General San Martín of La Plata, Buenos Aires, Argentina., Hernández N Daniel Velasco , Horiuchi Héctor R ,   Departament of Surgery, University Hospital General San Martín of La Plata, Buenos Aires, Argentina., Battista Santiago B De ,   Departament of Surgery, University Hospital General San Martín of La Plata, Buenos Aires, Argentina., Rivaletto Lucas A ,   Departament of Surgery, University Hospital General San Martín of La Plata, Buenos Aires, Argentina., Sabbatini Matías ,   Departament of Surgery, University Hospital General San Martín of La Plata, Buenos Aires, Argentina.
Published: August 2022

A trichobezoar is a rarely encountered mass of hair, wool, and similar material in the stomach and intestine of some patients with trichotillomania and trichophagia. The accumulated hair within the stomach and intestine is resistant to digestion, which occasionally presents as trichobezoar-induced bowel or gastric outlet obstruction. Trichobezoars are more common in paediatric age than adults, with up to 90% occurring in girls [1-3]. This report aims to describe the case of a young woman with an obstructive trichobezoar of the stomach and duodenum.
Clinicopathologic correlates of tumor deposits, lymph node harvest, lymph node metastasis, and lymph node ratio in colorectal cancer: The importance of mucinous tumor histology
Authors:   Pathology Department, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey., Gozde Kir , R Girgin Burcin ,   Pathology Department, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey., Tuce Soylemez ,   Pathology Department, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey., Gurhan Bas ,   Department of General Surgery, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey., Ilkay Tosun ,   Pathology Department, Umraniye Training and Research Hospital, Istanbul, Turkey., C Olgun Zeynep ,   Pathology Department, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey., Sema Gundogdu ,   Istanbul Medeniyet University School of Medicine, Istanbul, Turkey., Aman Gapbarov ,   Department of General Surgery, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey., Orhan Alimoglu ,   Department of General Surgery, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey.
Published: August 2022

Introduction: The presence of tumor deposits (TDs), number of harvested lymph nodes (LNs), LN metastasis, and LN ratio (LNR) are well-known prognostic factors in colorectal carcinoma. Materials and methods: The relationship between clinicopathologic parameters and the presence of TDs, number of harvested LNs, LN metastasis, and LNR was investigated in 278 consecutive patients who underwent surgery for colorectal adenocarcinoma. Results: Multivariate logistic regression analysis revealed that mucinous tumor histology and lymphovascular invasion (LVI) were independent risk factors for the presence of TD (p=0.016 and p=0.003, respectively). Age, tumor localization, and pT stage were statistically significant parameters affecting harvested LN number (p=0.002, p=0.007, and p=0.028, respectively). Only LVI was an independent risk factor for LN metastasis (p=0.001), whereas advanced age, mucinous tumor histology, and LVI were independent risk factors for higher LNR (p=0.033, p=0.042, and p=0.001, respectively). Conclusions: Our results revealed that mucinous tumor histology was an independent risk factor for the presence of TDs and higher LNR. In addition, LVI - which is a well-known prognostic factor- was also an independent risk factor for the presence of TD and higher LNR. Older age was found to be an independent risk factor for higher LNR. We found that the number of harvested lymph nodes was increased when the patients were younger, the tumor was located on the right colon, and the pT stage was advanced. These results have to be proven in larger cohorts with follow-up data. Keywords: colorectal cancer; mucinous tumor histology; tumor deposit; lymph node ratio; lymph node metastasis.
Role of NRAS upregulation as diagnostic marker in cholangiocarcinoma
Authors:   Department of Anesthesiology, Southeast University, Zhongda Hospital, Nanjing, China., Kang Zheng , Feifei Guo ,   Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Affiliated to Nanjing University Medical School, Nanjing, China.
Published: August 2022

Background: Cholangiocarcinoma (CCA) is the second leading primary liver cancer. Lacking of accurate diagnostic markers in response to chemotherapeutic treatment in CCA is one of the significant challenges in CCA personalized therapy. Protein-coding gene Neuroblastoma RAS viral oncogene homolog (NRAS) is one of the most reported mutations and overexpressed genes in CCA. The correlation between the mRNA expression level of NRAS and CCA tumorigenesis is still not detailed discussed. Thus, we evaluated the diagnostic and prognostic values of NRAS in CCA. Method: We downloaded transcriptional expression profiles from the Cancer Genome Atlas for pan-cancer analysis and further study between CCA and normal tissues. NRAS protein expression data were acquired from the Human Protein Atlas database. We employed the receiver operating characteristic (ROC) curve to assess the potential value of NRAS as a diagnostic marker. Kaplan-Meier method was performed to testify the NRAS on overall survival (OS). The STRING database was used to construct the protein-protein interaction networks. We also conducted functional enrichment analyses with the "Cluster Profiler" R package. Results: Overexpression of NRAS mRNA was observed in various cancers in pan-cancer analysis, including CCA patients. Our further study showed that both mRNA and protein expression of NRAS was hugely increased in CCA tissue compared to adjacent normal tissue. The upregulated expression of NRAS was associated with the tumor metastasis stage. ROC curve analysis indicated that with a cutoff level of 4.39, the sensitivity, specificity, and accuracy for NRAS differentiate CCA from pericarcinomatous tissue were 0.972, 0.999, and 0.999, respectively. Kaplan-Meier survival analysis indicated that overexpression of NRAS doesn't affect the OS of CCA patients. Function enrichment analyses proposed some co-expressed genes of NRAS in CCA. Conclusion: Overexpressed NRAS is strongly correlated with tumorigenesis of CCA. The present study suggests that NRAS can be potentially used as a diagnostic biomarker of CCA oncogenes. Keywords: cholangiocarcinoma; NRAS; diagnostic biomarker; tumorigenesis; metastatic stage.
Efficacité, innocuité et tolérance de l'association fixe d'ibuprofène (400 mg) plus caféine (100 mg) par rapport à l'ibuprofène, la caféine et un placebo dans la douleur aiguë
Authors: Weiser Thomas
Published: August 2022

L'association de l'ibuprofène à la caféine présente-t-elle des avantages par rapport à l'ibuprofène seul dans le traitement de la douleur aiguë ? Une étude randomisée, contrôlée contre placebo, en double aveugle a comparé l'efficacité, l'innocuité et la tolérance d'une association d'ibuprofène + caféine avec celles des substances seules ou un placebo dans la douleur aiguë, modérée à sévère. L'association était supérieure à tous les autres traitements en termes de réduction de la douleur pendant 8 heures, de délai d'action, de taux de répondants et de prise d'un antalgique de secours ; l'innocuité et la tolérance ont été démontrées. En conséquence, l'association d'ibuprofène et de caféine est une option thérapeutique supérieure à l'ibuprofène seul pour le traitement de la douleur aiguë.
Efficacia, sicurezza e tollerabilità della combinazione a dose fissa ibuprofene (400 mg) più caffeina (100 mg) rispetto a ibuprofene, caffeina e placebo per il dolore acuto
Authors: Weiser Thomas
Published: August 2022

La combinazione dell'ibuprofene con la caffeina offre dei vantaggi rispetto al solo ibuprofene nel trattamento del dolore acuto? Uno studio randomizzato, in doppio cieco, contro placebo ha confrontato l'efficacia, la sicurezza e la tollerabilità della combinazione ibuprofene più caffeina con quelle di ciascuna delle due sostanze presa singolarmente e di un placebo nel trattamento del dolore acuto da moderato a grave. La combinazione si è dimostrata superiore rispetto a tutti gli altri trattamenti in termini di sollievo dal dolore nell'arco di 8 ore, insorgenza dell'azione, tasso di responder e necessità di assumere un analgesico di soccorso aggiuntivo; sono state dimostrate anche sicurezza e tollerabilità della combinazione. Pertanto la combinazione ibuprofene più caffeina è un'opzione terapeutica superiore rispetto al solo ibuprofene per il trattamento del dolore acuto.
Effekt, säkerhet och tolerabilitet för den fasta kombinationen ibuprofen (400 mg) och koffein (100 mg) jämfört med ibuprofen, koffein och placebo vid akut smärta
Authors: Weiser Thomas
Published: August 2022

Är det fördelaktigt att kombinera ibuprofen med koffein, jämfört med enbart ibuprofen, vid behandling av akut smärta? En randomiserad, placebokontrollerad, dubbelblindad studie jämförde kombinationen ibuprofen + koffein med de enskilda substanserna eller placebo avseende effekt, säkerhet och tolerabilitet vid akut, måttlig och svår smärta. Kombinationen var överlägsen alla andra behandlingar vad gällde smärtlindring i 8 timmar, hur snabb verkan var, svarsfrekvens och intag av analgetikum som vidbehovsmedicinering; säkerhet och tolerabilitet påvisades. Sålunda är ibuprofen i kombination med koffein ett överlägset behandlingsalternativ jämfört med enbart ibuprofen vid behandling av akut smärta.