bluuebunny/crossref_metadata_2025 huggingface dataset:
TRADE AND INVESTMENT-LED GROWTH IN SOUTHERN AFRICAN DEVELOPMENT COMMUNITY (SADC)
Authors:   Botho University, Botswana, Mbulawa Strike
Published: July 2021

The growth in the gross domestic product (GDP) has been below zero within the Southern Africa Development Community (SADC) region in recent years. Some member states have consistently experienced negative growth rates for an extended period which has contributed to low growth for the region on average. The lack of consensus on the findings in literature requires further research work to be done to guide policymakers on the potential sources of growth. This study examines the contribution of trade and investment on growth in the context of SADC. It applies the autoregressive distributed lag (ARDL) model to test relationships in both short and long run using annual data for the period 1994 to 2019. Findings confirm the existence of the trade and investment-led growth hypothesis. There is a short run, long run, and joint causality from both explanatory variables to economic growth. Cointegration between growth, trade, and investment is confirmed. Specifically, an increase in investment spurs growth in both the short and long run. Investment expenditure seems to double the growth potential in the long run. Additionally, the study shows that an increase in trade openness retards growth which is consistent with the Prebisch-Singer hypothesis. Results suggest that policies that focus on the development and improvements in fixed investment, locally, help to drive the growth potential. The improvement of capitalization by manufacturing-oriented firms, as opposed to primary product-oriented firms, is ideal.
ECONOMIC EVALUATION OF PREVENTIVE HEALTHCARE: A COST BENEFIT ANALYSIS OF A PARENTING PROGRAM
Authors:   University of Ljubljana, Slovenia, Ponikvar Nina , Anderluh Marija ,   Department for Child Psychiatry of the Division for Paediatrics in Ljubljana, Slovenia, Kreslin Eva Strmljan ,   Mala ulica Family Centre, Slovenia, Marc Mojca ,   University of Ljubljana, Slovenia
Published: July 2021

The positive impact of parenting programs on the health and wellbeing of individuals and their immediate community has been confirmed in many studies. Often, and especially during the Covid-19 pandemics, prevention health programs are stalled due to other policy priorities. Costbenefit analysis (CBA) can be used for the economic evaluation of public health programs to support evidence-based health policies and allows the comparison of the monetized effects of programs across different societal domains. However, CBA requires a variety of data that are typically difficult to obtain. Using the Incredible Years (IY) parenting program case, we illustrate how CBA can be practically applied. For parenting programs, the positive effects arise exclusively in non-monetary form as benefits arising from avoiding adverse effects in society. We show how to monetize them by estimating the avoided costs of healthcare, educational, and other societal costs due to the program's implementation. At a 4% social discount rate, the economic net present value is positive and high, showing that the present value of the program's benefits exceeds the costs of the program by almost €800 thousand. The benefit-to-cost index of 5.6 confirms that every € invested in the program brings benefits of €5.6 in monetary terms. Cost-benefit analysis provides a convincing foundation for distributing public funds as it allows for a comparison of fieldrelated programs and programs from different fields. Consequently, they increase any public policy's effectiveness and efficiency, but especially preventive health policy.
To study the attitude on marital adjustment of selected respondents from Mehsana and Ahmadabad city
Authors: Vyas Jiju N. , Tiwari Neha , Chaudhari Neeta
Published: July 2021

The present study was conducted in Mehsana (urban and rural area) and Ahmadabad (urban and rural area) city. The sample size was 720 women and they were selected from both the cities. The women who were educated upto 12th standard, graduate and post graduate were randomly selected for the study. Purposive random sampling technique was used for selection of the sample. The research design for the present paper was two pronged approach. A descriptive survey with pre-tested, validated interview schedule was used to acquire the information needed to study the attitude on marital adjustment.
Food for therapy: Naturopathic dietetics approach !
Authors: Avinash Prachi
Published: July 2021

Food plays one of the most important roles in maintaining good health and managing diseases. Plant food constitutes a significant part of our diet providing various important nutrients required by body for adequate growth and development. The philosophy about therapeutic benefits of food, it being health promoting beyond its nutritional value has gained acceptance. It is a common practice to envisage that a person can eat whatever he/she feels like and as long as no direct bad after-effects are felt, the matter deserves no attention. But in reality, this is only a wrong notion and it beckons the beginning of a disease or disorder. Regularity, punctuality, thorough chewing, feeling of hunger and avoiding hurry, worry, tension and emotion while taking meal are very essential to derive maximum benefits and best utilization of nutrients from the food intake.With the many different types of diets and lifestyles based on both ideologies and allergies, a lot of nutritional choices are available to the consumers now-a-days. A naturopathic diet can be beneficial in preventing illness, improving metabolism and overall health. It works on principle of foods intheir natural state, i.e. foods free from artificial ingredients, chemical preservatives and additives. In modern times, because of advancement in technology, familial advices, natural/ synthetic products on sale, media spins, muddled messages, etc. the people are bound to get complicated and confusing cognizance regarding how to maintain health through diet and nutrition. It undeniably becomes perplexing when we have to decide what we should actually consume and what should we avoid. Thus, it was felt necessary to compile the knowledge of naturopathy and dietetics overlap through this paper, so as to provide an insight of naturopathic dietetics.
Role of alternate healthy eating index (AHEI) in communicating the quality of diet
Authors: Mohandas Krishna , Prema L.
Published: July 2021

The food habits of global population has been evolving in such a way that makes unhealthy foods cheaper and widely available and healthy foods costly and less available. Being surrounded by such foods and living in an environment with lesser requirement for physical activity is the primary reason for the pandemic explosion in overweight and obesity. This study is an attempt to analyze the quality of diet with an aim to study the significance of Alternate Healthy Eating Index (AHEI) in predicting the quality of dietary intake. Methodology: The study was conducted in 66 respondents (44 females and 22 males) aged 18-65 years with BMI between 23 kg/m2 to 50 kg/m2. The respondent’s data were collected using a pretested standard questionnaire. The nutrient consumption was calculated from the 24 hour recall and the AHEI scores were derived from recall and food use frequency data. The data were analysed using SAS software. Results: The intake of Energy, protein, fat and carbohydrates were more than their requirement while intake of fibre was not meeting the requirement. The AHEI scores obtained ranged from 36 to 76 with a mean value of 55.6 ± 9.54. A positive linear association for AHEI with BMI (0.0362) and energy intake (0.13) was established through Pearson’s correlation while the association was negative with BMR (-0.14). Paired t test comparing AHEI against the difference between intake and requirement of macronutrients revealed that when the diet quality was good (as indicated by AHEI>51), the difference in intake exhibited a significant linear relationship with p values <0.001 while no relation was established when the diet quality was poor. Conclusion: AHEI encompasses all nutrients and food groups relevant to metabolic health and it can be used as a good tool to assess the quality of dietary habits of overweight and obese subjects.
Matriz Avaliativa do Vínculo Longitudinal na atenção primária em saúde: validação estatística em um território de saúde do Município do Rio de Janeiro, Brasil
Authors: Cunha Elenice Machado da , Vargens José Muniz da Costa , Marques Marcio Candeias , Andrade Gabriela Rieveres Borges de , O’Dwyer Gisele
Published: July 2021

Resumo: Consonante com o processo de institucionalização da avaliação da atenção primária no Brasil, foi desenvolvida a Matriz Avaliativa do Vínculo Longitudinal (MAVIL), instrumental avaliativo simples e conciso. A MAVIL estrutura-se a partir das três dimensões do conceito de vínculo longitudinal: Dimensão 1 - reconhecimento da unidade básica de saúde (UBS) como fonte regular de cuidados, Dimensão 2 - relação interpessoal profissional/paciente e Dimensão 3 - continuidade da Informação. Consiste em um conjunto estruturado de 12 critérios, 20 indicadores e respectivas questões e itens de verificação, submetido a várias etapas de validação. O presente artigo apresenta a validação estatística da aplicação MAVIL em duas UBS de um território de saúde a fim de respaldar as futuras aplicações e averiguar também a capacidade do instrumento para captar diferenças no perfil do vínculo longitudinal entre UBS. O método consistiu nas seguintes definições: desenho da amostra, escolha da métrica, análise descritiva dos dados e teste comparativo de médias, por meio da aplicação do teste de normalidade e de estatística não paramétrica. Como resultados: a amostra por estrato, junto à opção da soma dos pontos dos itens da MAVIL como métrica, possibilitou descrever o perfil do vínculo longitudinal para os três recortes: território e UBS A e B. Para verificar a capacidade da MAVIL em captar diferença no perfil de vínculo longitudinal, testou-se a hipótese da normalidade dos dados a partir do teste de Kolmogorov-Smirnov. Rejeitada a hipótese da normalidade, optou-se pelo teste não paramétrico de Wilcoxon para comparar as UBS. Para Dimensão 1 e Dimensão 2, constatou-se a semelhança de perfil, contudo, para Dimensão 3, houve diferença significativa, atestando a sensibilidade da MAVIL.
Insatisfação com o trabalho, aspectos psicossociais, satisfação pessoal e saúde mental de trabalhadores e trabalhadoras da saúde
Authors: Sousa Camila Carvalho de , Araújo Tânia Maria de , Lua Iracema , Gomes Mariana Rabelo , Freitas Kátia Santana
Published: July 2021

Resumo: O objetivo foi avaliar a relação da insatisfação no trabalho e ocorrência de transtornos mentais comuns (TMC), considerando os aspectos psicossociais do trabalho e a satisfação pessoal (SAP). Estudo transversal, em amostra de 3.084 trabalhadores/as de saúde de cinco municípios baianos. Empregou-se análise de modelagem de equações estruturais, estratificada por gênero. A insatisfação com o trabalho foi a variável de exposição principal. Os TMC, variável desfecho, foram avaliados pelo Self-Reporting Questionaire (SRQ-20). Satisfação pessoal, avaliada por questões do World Health Organization Quality of Life (WHOQOL), e os aspectos psicossociais estressores (AE) e protetores (AP), mensurados pelo Job Content Questionnaire (JCQ) e pela escala Effort-Reward Imbalance (ERI), foram tratadas como variáveis latentes. A insatisfação com o trabalho associou-se positivamente aos TMC, entre homens (0,160; IC95%: 0,024; 0,295) e mulheres (0,198; IC95%: 0,135; 0,260). Os AE associaram-se positivamente à insatisfação com o trabalho e aos TMC, enquanto os AP associaram-se negativamente a esses dois eventos, entre homens e mulheres. A insatisfação com o trabalho mediou o efeito dos aspectos psicossociais e da SAP na ocorrência de TMC. O modelo final apresentou bom ajuste nos grupos analisados. Elevada insatisfação, presença de aspectos psicossociais estressores, carência de aspectos protetores e insatisfação pessoal associaram-se aos TMC direta ou indiretamente. Os resultados reforçam a necessidade de ações voltadas à proteção da saúde mental no trabalho em saúde com o redesenho dos aspectos nocivos identificados e fortalecimento dos aspectos associados à menor ocorrência de TMC.
EVALUATION OF FALL RISK FACTORS PRESENT DURING INSTITUTIONALIZATION OF ELDERLY PEOPLE
Authors: Baixinho Cristina Rosa Soares Lavareda , Dixe Maria dos Anjos Coelho Rodrigues
Published: July 2021

ABSTRACT Objectives: to describe the development and validation of the Scale of Practices of Evaluation of Fall Risk Factors during Institutionalization of Elderly People and to describe the practices of evaluation of communication of fall risks to institutionalized elderly people. Methods: methodological study, which allowed construction and determination of the psychometric properties of the Scale of Practices of Evaluation of Fall Risk Factors during Institutionalization of Elderly People, which was carried out in six long-term care institutions for elderly people, in 2018. Results: the scale showed satisfactory internal consistency, with a Cronbach’s alpha of 0.949. It was designed to have three dimensions: practices of evaluation of biophysiological risk factors; practices of communication and training; and practices of evaluation of risks related to elderly people’s putting on clothing and footwear. Conclusions: the risk factors that had their value recognized were related to mobility. There is not proper recognition of the importance of information about fall risk factors and communication between elderly people and health teams during institutionalization.
STROKE IN COVID-19 PATIENTS: A SCOPING REVIEW
Authors: Cruz Neto João , Feitosa Emanuel Messias Silva , Cunha Brenda Silva , Nascimento Maria Naiane Rolim , Félix Nuno Damácio de Carvalho
Published: July 2021

ABSTRACT Objective: to map the scientific production on patients infected by COVID-19 and the occurrence of stroke. Method: a scoping review, according to the framework proposed by the Joanna Briggs Institute, using the LILACS, MEDLINE, WoS, EMBASE, CINAHL and SCOPUS databases, from April to September 2020. The following keywords were used: coronavirus infections, stroke, nervous system diseases and inpatients, based on the Medical Subject Headings. Results: 24 studies that evidenced specific clinical symptoms of stroke such as dysarthria, facial paralysis, sensory deficit, headache, hemiparesis and ataxia in patients with COVID-19 were included. The association between stroke and COVID-19 was found by the following exams: C-reactive protein, D-dimer, computed tomography and, magnetic resonance, among others, as well as by care procedures focused on the findings in the exams, associated with three clinical outcomes, based on the brain ischemia zone affected and the time of viral manifestation of each patient. Conclusion: the specific clinical manifestations of patients who suffered a stroke after COVID-19 were mapped, as well as diagnostic procedures and therapies used, in addition to identifying neurological damage based on the clinical outcome of these patients.
Renal biopsy in children with IgA vasculitis
Authors: Kara Mehtap Akbalik , Kiliç Beltinge Demircioğlu , Büyükçelik Mithat , Balat Ayşe
Published: July 2021

Abstract Introduction Henoch-Schönlein purpura nephritis (HSN) is defined as Henoch-Schönlein purpura with kidney involvement, including hematuria and/or proteinuria. The aim of this study was to evaluate the data of HSN patients who underwent renal biopsy, and compare the main clinical and laboratory parameters that may affect renal biopsy findings, treatment protocols, and short- and long-term outcome of those patients. Methods Biopsies performed in 72 HSN patients between January 2007 to January 2017 were retrospectively evaluated. They were divided into two groups according to renal biopsy classification of the International Study of Kidney Disease in Children. Renal outcome, clinical and laboratory parameters, treatment protocols, and outcome were compared between groups. Short- and long-term follow-up of patients were evaluated. Results Of 72 patients, 47 were male (65.3%) and 44 (61.1%) were ≤10 years of age. Neutrophil-lymphocyte ratio was found higher in patients with scrotal involvement (p=0.042). Short-term unfavorable outcome was significantly higher in patients with scrotal involvement (p=0.038). Patients with hypertension and decreased creatinine clearance were found to have more unfavorable outcomes in long-term follow-up (p=0.029, p=0.040). Conclusion Cyclosporin-A and cyclophosphamide could be effective in steroid unresponsive HSN patients. Patients with scrotal involvement, decreased creatinine clearance, and hypertension should be closely monitored for sequelae of HSN.
Proposições do Banco Mundial para a política educacional brasileira (2016-2018)
Authors: Guerra Dhyovana , Figueiredo Ireni Marilene Zago
Published: July 2021

Resumo O presente artigo tem por objetivo discutir as proposições do Banco Mundial para a Política Educacional brasileira entre os anos 2016 e 2018. Para tanto, são discutidos excertos de quatro documentos emanados do Banco Mundial (2016, 2017a, 2017b, 2018), um Organismo Internacional que atua na concessão de empréstimos e oferece assessoria técnica aos países membros, assim como desempenha uma função expressiva na produção intelectual, por meio da elaboração de um conjunto de documentos que subsidiam a implementação das políticas educacionais. No estudo realizado constata-se a ênfase do Banco Mundial na reforma do Estado e da educação, cujo atendimento das necessidades educacionais básicas é considerado como uma das variáveis fundamentais para administrar os níveis de pobreza. Por meio da educação, que promoveria a aquisição de habilidades e competências durante a formação escolar, seria possível conseguir emprego e, consequentemente, obter renda para redução da pobreza. Ao que tudo indica, a educação, nos quatro documentos do Banco Mundial analisados, é concebida como elemento central para o alívio dos efeitos da pobreza e para promoção da equidade. A educação também é apontada como uma das responsáveis pela ineficiência dos gastos públicos no Brasil, o que tende a expressar um alinhamento ao projeto neoliberal de sociedade, a partir da década de 1990.
Construção de diagnósticos de enfermagem para pessoas com lesão medular em reabilitação
Authors: Clares Jorge Wilker Bezerra , Guedes Maria Vilaní Cavalcante , Freitas Maria Célia de
Published: July 2021

RESUMO Objetivo: Construir enunciados de diagnósticos de enfermagem da Classificação Internacional para a Prática de Enfermagem (CIPE®) para a especialidade de reabilitação em lesão medular, com base no Modelo de Adaptação de Callista Roy. Método: Pesquisa descritiva desenvolvida em etapas sequenciadas de identificação e mapeamento cruzado de termos relevantes para o cuidado com a prioridade de saúde, construção e mapeamento cruzado de enunciados de diagnósticos de enfermagem, com base na CIPE®, e categorização dos diagnósticos segundo os modos adaptativos. Resultados: Foram elaborados 92 enunciados de diagnósticos de enfermagem, dos quais 66 foram classificados no Modo Fisiológico, 12 no Modo Papel Funcional, 10 no Modo Autoconceito e quatro no Modo Interdependência. Conclusão: Os diagnósticos de enfermagem elaborados retratam focos de atenção para o cuidado de enfermagem a pessoas com lesão medular em reabilitação, contribuindo para o direcionamento das ações da assistência de enfermagem de forma sistematizada, individualizada e resolutiva.
Use of recycled aggregates from civil construction in self-compacting mortar
Authors: Valle Fernanda Rodrigues Santos , Gonçalves Paulo Cesar , Ranieri Maria Gabriela A. , Melo Mirian de Lourdes Noronha Motta , Santos Valquíria Claret dos
Published: July 2021

abstract: The utilization of wastes from demolition in civil construction in self compacting concrete (SCM) has the potential to reduce both the environmental impact and financial cost. In this context, this article aims to verify the behavior of the incorporation of recycled aggregates of civil construction in the mix designs of self-compacting mortar (SCM) in replacing cement, presenting as an interesting alternative to natural raw materials. This study used the EMMA® software to optimize the choice of percentages of fine recycled aggregates when replacing cement. The proportions chosen were 0%, 5%, 15%, and 25%, through the analysis of the granular packing curve of the respective mix designs. The proportion of 0% has in its composition cement, metakaolin, sand, superplasticizer (SP) and water. The parameters obtained, through tests in the fresh state of the mini-slump and mini-funnel V, certified the samples as SCM. The compressive strength and flexural tensile strength tests in the hardened state demonstrated a reduction in mechanical properties of the material with cement replacement. It is concluded that the waste used brick and ceramic can be added in replacement to the cement in SCM without significant loss of properties in the fresh and hardened state.
The effect of social distancing due to the COVID-19 on adult and elderly exercises. Exercise and social distancing
Authors: Ritter Alexandre Luis
Published: July 2021

Objective: Social distancing due to COVID-19 pandemic could lead people to lower exercise engagement. The objective of this paper is to describe and compare the types of physical exercises participants were engaged, as well their frequency, duration, and intensity, in three different periods: 2019 (1), Jan/Feb 2020 (2), and during the social distancing period due to the COVID-19 pandemic (3). Methods: This is a cross-sectional study and its population was composed of adults and elderly from a public recreation center. The participants were invited by social media to answer a survey on Google Forms dealing with the characteristics of the physical exercises practiced in the three periods covered in this research. The survey was made available during October 2020. Results: Took part in this study 194 participants (63.49±14.14 years; 93.2% women). During period 1 the most practiced exercises was strength/aerobic class, twice/week, from 46 minutes to 1 hour/session, at intensity 6. During period 2, walking was the most mentioned, three times/week, from 31 to 45min/session, at intensity 7. During period 3, strength/aerobic class was the most frequent, three times/week, from 31 to 45min/session, at intensity 5. Conclusion: When compared to the period 1, there was a decrease (p <0.05) in the total time of exercise in periods 2 and 3, and there was also, in these last two periods, a decrease in the number (p <0.05) of participants who reached WHO guidelines of 150min/75min per week of exercise.
Creatividad y Enfoques de Aprendizaje en Estudiantes Universitarios
Authors: Freiberg Hoffmann Agustín , S Vigh Carlos , Fernández-Liporace Mercedes
Published: July 2021

Introducción: Mejorar el aprendizaje de los estudiantes y adaptarlo a las demandas del mercado laboral actual es un tema de gran interés planteado por distintos organismos internacionales. Se busca así que los alumnos alcancen un aprendizaje profundo de los contenidos académicos y que a su vez desarrollen su capacidad creativa para la resolución de problemas.

Objetivo: Analizar los enfoques de aprendizaje –Profundo y Superficial– y la creatividad –proceso creativo y personalidad creativa– en estudiantes universitarios según variables sociodemográficas y académicas.

Método: Se empleó un diseño no experimental y transversal. Se respondió a un objetivo de diferencias entre grupos y a otro explicativo. Participaron 301 estudiantes universitarios de Psicología (51%) e Ingeniería (49%).

Resultados: Se registraron diferencias significativas en los enfoques profundo y superficial: el primero a favor de las mujeres, y el segundo favorable a los varones. En relación con la creatividad, se observó una diferencia significativa en la personalidad creativa a favor de los varones, y del proceso creativo a favor de los estudiantes de Psicología. Por otra parte, el rendimiento académico fue explicado negativamente por el enfoque superficial (β=-.276) y positivamente por el proceso creativo (β=.185).

Conclusiones: Para mejorar el rendimiento académico se necesita aplicar estrategias de enseñanza y evaluación que desestimulen el aprendizaje superficial y promuevan el proceso creativo en los estudiantes. Los cambios en las prácticas educativas deberán, además, enfocarse en mejorar el aprendizaje profundo y la creatividad para ajustar el perfil profesional de habilidades de los egresados al requerido actualmente por el ámbito laboral
Cine y nación: negociación, construcción y representación identitaria en Colombia
Authors:   Universidad de Antioquia, Puerta Domínguez Simón
Published: July 2021

Este libro busca develar las mediaciones a partir de las cuales las imágenes cinematográficas son producidas y entran a participar en la generación de percepciones sobre la identidad nacional, al relacionar los implicados en la industria y las narrativas que son llevadas a la pantalla con los procesos históricos, económicos, políticos y socioculturales que han sucedido en Colombia durante todo el siglo xx, que es el siglo que ha sido registrado por el cine. De igual modo, una profundización en la legislación y en las lógicas a partir de las cuales las obras son legitimadas o rechazadas por el mismo ente institucional, las distribuidoras y exhibidoras privadas, y el mismo público, son una preocupación imperativa del análisis, para determinar cómo se van moldeando los discursos fílmicos y qué papeles se van adjudicando a las obras a lo largo de este proceso, interminable, de discusión acerca de la afinidad colectiva de la nación. El cine se plantea entonces como un escenario a partir del cual se hace posible la indagación sobre la identidad nacional, al ser los procesos creativos de las obras y los productos que se prestan al consumo simbólico del cuestionamiento identitario, proyectos imbricados en lógicas e intereses que se superponen en la imagen final, develando las negociaciones y posturas que la heterogeneidad que constituye la comunidad nacional postula como legítimos y representativos de Colombia y sus ciudadanos.
Application of the in silico approach in the study of critical genes predicting chemotherapeutic response to oxaliplatin in treatment of prostate cancer (literature reviev)
Authors: Loginova M. V. , Pavlov V. N. , Gilyazova I. R.
Published: July 2021

Prostate cancer is the leading cause of death among men. Existing prognostic factors make it possible to differentiate the degree of malignancy of tumors with high metastatic potential. Currently, the treatment of high-grade tumors is carried out with hormonal therapy, to which taxanes are added, when the malignant neoplasm becomes resistant to castration. Studies with other anti-cancer agents did not take into account the genetic background of the tumors, and most of the trials showed low response rates. The article describes an in silico approach for screening drug candidates that can be used as an alternative to taxanes. Researched 86 genes that distinguish between high and low grade tumors, and identified several genes that correlated with chemosensitivity. As an example, a set of six genes has been proposed the expression levels of which can predict cell sensitivity to oxaliplatin. The study demonstrates the relevance of an approach to the treatment of high-grade prostate cancer and new biomarkers for predicting clinical tumor response.
Complications of robot-assisted and laparoscopic partial nephrectomy
Authors: Rakul S. A. , Pozdnyakov K. V. , Eloev R. A.
Published: July 2021

Objective: to analyze complications after laparoscopic and robotic-assisted partial nephrectomy.

Materials and methods. In our study was included 246 cases. Intra- and postoperative complications were studied after nephron-sparring surgery. The laparoscopic approach was used in 68 (27.3 %) cases, the robot-assisted - in 178 (71.5 %) cases. Intraoperative complications were assessed according to the Rosenthal classification, postoperative complications - according to the Clavien-Dindo classification.

Results. The overall incidence of intraoperative complications was 12.6 %. The most frequent intraoperative complication was bleeding that did not require blood transfusion (grade I) - 5.69 % (laparoscopic approach - in 3 (4.41 %) cases, robot-assisted approach - in 11 (6,18 %) cases). Bleeding requiring blood transfusion and injuries of internal organs, which were restored intraoperatively (grade II), were recorded in laparoscopic and robot-assisted approaches in 4.41 % and 2.25 % of cases, respectively. Complications leading to the loss of organ (nephrectomy, splenectomy) were observed in 2.94 % and 4.49 % of cases, respectively. Intraoperative deaths (grade IV) were not registered.

The incidence of postoperative complications was 18.29 %. Minor complications (Clavien-Dindo ≤II) were detected in 16 (6.5 %) patients (laparoscopic approach - 7.35 %, robot-assisted approach - 6.18 %). Serious complications (Clavien-Dindo ≥III) were detected in 29 (11.79 %) cases (with laparoscopic approach - 14.71 %, robot-assisted - 10.67 %). In the group of tumors with the RENAL index 4-6, the incidence of postoperative complications was 14.7 % with the laparoscopic approach, and 7.1 % with the robot-assisted approach; in the RENAL 7-9 group - 21.9 % and 13.0 %, respectively. In the group of tumors of high complexity (RENAL 10-12), only the robot-assisted approach was used, the incidence of postoperative complications was 22.0 %.

Conclusion. Partial nephrectomy for kidney tumors is an effective and safe surgical technique. The incidence of complications when using the laparoscopic approach is higher than when using the robot-assisted technique in groups of tumors of simple and medium complexity. For tumors of high complexity, robot-assisted approach is a priority. The largest number of serious complications is observed with partial nephrectomy with complex tumors.
Markers of bladder cancer: their role and prognostic significance (literature review)
Authors: Belyakova L. I. , Shevchenko A. N. , Sagakyants A. B. , Filatova E. V.
Published: July 2021

This review article is devoted to the main problems of early diagnostic and prognosis of non-muscle-invasive bladder cancer, which accounts for 75 % of all newly detected cases of bladder cancer according to statistics. Chromosomal disorders that have been detected in urothelial cells can lead to the development of non-muscle-invasive bladder cancer. The review highlights the main problems of existing diagnostic systems for bladder cancer, their disadvantage and limitations of use in practice. Special attention is given to tumor stem cells, which are actively involved in the development of relapses of malignant neoplasms, and, also play an important role in the development of chemo - and radioresistance of tumor cells. Their significance in the diagnosis, detection of disease recurrence and the possibility of using the data obtained to adjustment therapeutic methods of treatment in oncology is one of the main tasks in cancer pathology.
Pharmacoeconomic aspects of the therapy for moderate and severe psoriatic arthritis
Authors: Rudakova A. V. , Tolkacheva D. G. , Sokolova V. D.
Published: July 2021

Objective: to perform cost-effectiveness analysis of the treatment for adult patients with psoriatic arthritis (PsA) with a Russian interleukin- 17А inhibitor netakimab in comparison with other biologic disease-modifying antirheumatic drugs (bDMARDs) and targeted synthetic disease-modifying antirheumatic drugs (tsDMARDs) and to evaluate the influence of the inclusion of netakimab in the therapy for PsA on the budget of the Russian healthcare system.

Material and methods. The evaluation of cost-effectiveness was performed from the position of the Russian healthcare system for patients with moderate and severe PsA. The evaluation was performed based on the results of the network meta-analysis of the randomized clinical studies. The criterion of clinical effectiveness included the changes in the condition of the joints by the criteria of the American College of Rheumatology (ACR20, ACR50, and ACR70) and changes in skin symptoms by the index of the prevalence and severity of psoriasis (PASI 75 and PASI 90) with a recalculation into quality-adjusted life-year (QALY). The time horizon of the cost-effectiveness analysis was 2 years. The calculation was based on the registered prices and VAT. If there was an original drug and a biosimilar registered on the pharmaceutical market, the calculation was based on the median of the registered prices. The budget impact analysis of the influence of netakimab inclusion in the therapy for patients with PsA was performed considering the structure of the prescription of bDMARDs and tsDMARDs that was determined in the pharmaco-epidemiological study conducted in the Russian Federation in 2020. The analysis was performed for patients that received medication by the scheme of reimbursement. The time horizon of the study was 3 years old.

Results. In the base-case analysis, the cost-effectiveness ratio for netakimab was 1.210 mln rub/QALY (by 66.2–88.5% lower than in cases when comparison drugs were used). The budget impact analysis showed that the inclusion of netakimab in the therapy for PsA could reduce the costs by 376.60 mln rub (21.1%). Considering budget saving, the number of additional patients that can be treated will increase by 26.7% within 3 years.

Conclusion. Netakimab is characterized by higher cost-effectiveness in comparison with other bDMARDs (adalimumab, golimumab, guselkumab, ixekizumab, infliximab, secukinumab, ustekinumab, certolizumab pegol, etanercept) and tsDMARDs (apremilast, tofacitinib) prescribed in the Russian Federation for patients with PsA. The inclusion of netakimab in the therapy for PsA will reduce the financial burden on the healthcare system.
Systematic computer analysis of published literature on nutritional support for vaccination
Authors: Chuchalin A. G. , Torshin I. Yu. , Gromova O. A.
Published: July 2021

A range of 6700 publications from the PubMed database on the association of micronutrient supply and results of antibacterial and antiviral vaccination was reviewed by the method of topologic and metric analysis. This method allows for a selection of features (i.e. key words) by their informativity, the establishment of the most informative that provide the basis for “synthetic” features and algorithms, or the classification of the reviewed text by the relevance to the subject of the study. The results of fundamental studies showed that folates, vitamins A, D, and B12 are the regulators of mitosis of T and B-lymphocytes that exert the functions of the acquired immunity. Such microelements as zinc, iron, selenium, manganese, and omega-3 polyunsaturated fatty acid support the functioning of T and B-lymphocytes (energy metabolism, intracellular signal transmission, and transcription). Clinical studies showed that the support of vaccination with the specified micronutrients not only increases the titre of the respective antibodies to viral and bacterial pathogens but can also prevent unfavorable effects from vaccination. The administration of micronutrients before and after vaccination will contribute to a decrease in the mortality rate and severity of the pathology development (in case of disease). A systematic analysis allowed the authors to determine the perspectives of the proposed measures for an increase in the effectiveness and safety of vaccines, including COVID-19. Additional micronutrient supply contributes to an increase in the effectiveness and safety of vaccination. The application of specialized vitamin and mineral complexes during vaccination is economically feasible and reduces the vaccination risks for patients with polyhypoavitaminoses.
Developing Software of Global Optimization Method Based on Grey Wolf Optimizer
Authors: Panteleev A.V. , Belyakov I.A.
Published: July 2021

This article discusses the development of software that allows to simulate the algorithm of the “Grey Wolf Optimizer” method. This algorithm belongs to the class of metaheuristic algorithms that allow finding a global extremum on a set of admissible solutions. This algorithm is being the most efficiently used in a situation where the cost function is specified in the form of a black box. The algorithm belongs to both bioinspired algorithms and to the class of algorithms of Particle Swarm Optimization. To analyze the efficiency of the algorithm, software was created that allows to vary the parameters of the method. The article contains examples of the program’s work on various test functions. The purpose of the program is to collect and analyze statistical results, making possible to evaluate the final result. The program provides to build graphs that make it possible to make a more thorough assessment of the results obtained. The program has a step-by-step function that allows one to analyze the specifics and features of the algorithm. Analysis of statistical data provides more detailed selection of the parameters of the algorithm.
Comparing Digital Library Job Requirements and Digital Library Course Curriculum: An Indian Perspective
Authors: Kumari Nisha , Mishra Shesh
Published: July 2021

The main purpose of the study is to compare the digital library job requirements and the curriculum offered in Indian LIS departments. Data were obtained from two sources: 180 job advertisements obtained through online job sites and course outlines obtained from the websites of 21 universities. The content analysis method was followed in the research for data analysis. The findings indicate that employers demand good communication skills and ability of working on digital library software, handling library management software, knowledge of basic computer skills, programming and markup languages. Job ads also indicate that a bachelors’ and masters’ degree programme in library and information science are the minimum essential requirements for employing digital library professionals. The study also found that there is no separate digital library programme offered whereas digital library course contents are integrated into BLIS & MLIS programmes. The digital library topics such as training students in using library management software, digital library software and content management systems; creating databases using MySql; website designing are offered at both bachelor’s and master’s degree levels. This paper compares what is demanded in the job market and what is offered by LIS departments and found that the curriculum does not fully address the needs of the job market, as certain topics such as troubleshooting and problem solving skills were seen missing from the Indian LIS curricula.
Altmetrics Linked Scholarly Information from Dimensions.ai Datasets for the Top 100 LIS Articles
Authors: Vysakh C. , Rajendra Babu H.
Published: July 2021

This paper examines the presence of Library and Information Science articles in social media platforms by considering the top 100 highly socially cited articles from the Dimensions database. The study examines the association between major metrics. Data were collected from Dimensions.ai, Altmetrics.com, WoS, Google Scholar, and analyzed. The findings suggest that all the 100 LIS articles have got at least one mention from nine different social media platforms with increased attention from Mendeley and Twitter. The article “Objectivity and realms of explanation in academic journal articles concerning sex/gender: a comparison of Gender studies and the other social sciences” authored by Therese Soderlund et al., has been the top socially cited article in Dimensions with an altmetricss attention score of 684. The study found a weak positive correlation between social media citation with major citations from Web of Science (r=0.19), Google Scholar(r=0.18) and Dimensions(r=0.19). This is the first of its kind study to measure the social media attention of LIS articles based on the Dimensions dataset and the result gives more insights to LIS authors for evaluating the societal impact of their research using altmetricss indicators.
Why Do My Squiggles Look Funny? A Gallery of Compromised Seismic Signals
Authors: Ringler Adam T. , Mason David B. , Laske Gabi , Storm Tyler , Templeton Mary
Published: July 2021

Seismic instruments are highly sensitive and capable of recording a large range of different Earth signals. The high sensitivity of these instruments also makes them prone to various failures. Although many failures are very obvious, such as a dead channel, there are other more subtle failures that easily go unnoticed by both network operators and data users. This work documents several different types of failure modes in which the instrument is no longer faithfully recording ground-motion data. Although some of these failure modes make the data completely unusable, there are also a number of failures in which the data can still be used for certain applications. Of course, the ideal situation is to identify as soon as possible when data become compromised and to have the network operator fix the station. However, knowing how the data became compromised can also help data users to identify if the data can still be used for their particular application. This work in no way attempts to exhaustively document recording failures but rather to communicate examples and equip the reader with ways of identifying failure modes.
“Passando a boiada”
Authors: Ribeiro Camila Belizário , Almeida Maria Clotilde
Published: July 2021

O presente artigo tem como objetivo discutir alguns aspectos dialógicos e interdiscursivos percebidos em textos publicados como resposta ao discurso proferido pelo Ministro do Meio Ambiente Ricardo Salles, em 22 de abril de 2020. Para tanto, optamos pela abordagem qualitativa, à luz do paradigma de Análise do Discurso. Considerando o grande número de publicações de gêneros variados, resultantes da grande polêmica gerada pelo referido discurso, selecionamos três textos dos gêneros Nota de Posicionamento, Anúncio e Charge, visando exemplificar esta diversidade. Nossa discussão possui como base teórica os conceitos de Subjetividade, Dialogismo, Polifonia, Interdiscurso e Heterogeneidade (AUTHIER-REVUZ, 2004, 2011; BAKHTIN, 1990, 2003; BRANDÃO, 2015; ORLANDI, 2003). Uma vez que dois dos textos escolhidos para este corpus consistem em textos multimodais, também nos apoiamos nas noções de Multimodalidade e Retórica (Almeida, 2016, 2019; Tseronis; Forceville, 2017). Como resultado deste trabalho, foi possível, observar alguns aspectos do processo dialógico entre os textos selecionados e o discurso-fonte, assim como o papel do interdiscurso e da memória discursiva no processo interacional. Ademais, tendo em vista o caráter multimodal dos gêneros Charge e Anúncio, assim como a própria natureza metafórica, neste contexto, da expressão “passar a boiada”, recorremos ao debate de alguns mecanismos retóricos e argumentativos, a exemplo da heterogeneidade mostrada, do texto idiomático figurativo à luz da teoria da metáfora conceitual.
dimensão social na poesia de Ferreira Gullar e na de Tarso de Melo
Authors: Neto Henrique Duarte
Published: July 2021

O objetivo principal deste artigo é o de pensar de que forma há a ressonância da vida social brasileira na poesia de Ferreira Gullar (2001) e na de Tarso de Melo (2017), especificamente nas obras: Dentro da noite veloz, do primeiro, e Íntimo desabrigo, do segundo. Também se expõe a hipótese interpretativa de que em ambos surge uma espécie de “neorrealismo”, mas muito mais agudo e desenvolvido em Ferreira Gullar, com sua sede pelo referencial, pela realidade em toda a sua crueza. Por fim, conclui-se que ambos os poetas retratam de maneira contundente o contexto social brasileiro, com grande vigor expressivo e gerando poemas que tendem a permanecer não só enquanto retrato de uma época, mas, nos melhores casos, como produções artísticas de alto valor estético.
obra de…
Authors: Duarte Miguel de Ávila
Published: July 2021

Tomando como ponto de partida o poema-livro Odisseia Vácuo do performer, artista plástico e poeta contemporâneo Renato Negrão, o presente artigo pretende discutir questões relativas ao cânone artístico-literário, as possíveis relações entre a apropriação como procedimento de escrita e de criação e a apropriação cultural no contexto da diáspora africana e, por fim, como tais questões interferem nos próprios atos de nomeação. Para tanto, são construídos uma série de diálogos: com a epopeia fundadora de Homero; com o modernismo antropofágico; com a literatura de apropriação contemporânea estadunidense; com as propostas de Wölfflin e Valéry de histórias da arte e da literatura “sem nomes”; com o enredamento do primitivismo vanguardista e da invenção da colagem no primeiro cubismo; com a crítica contemporânea da apropriação cultural.
“A máquina do mundo” em 3D: Drummond, leitor de W.H. Auden / “A máquina do mundo” in 3D: Drummond, reader of W.H. Auden
Authors: Almeida Cleber Ranieri Ribas de
Published: July 2021

Resumo: O poema “A Máquina do Mundo” de Carlos Drummond de Andrade é interpretado pela crítica, no que diz respeito ao uso de intertextos, como um poema marcado pelo diálogo subliminar com a Divina Comédia de Dante Alighieri e com Os Lusíadas de Luís de Camões. Em contraposição a esta reiterada interpretação do poema, tentaremos demonstrar a hipótese segundo a qual o cenário de “A Máquina do Mundo” foi construído e imaginado a partir de uma releitura do cenário do poema “As I Walked Out One Evening”, do poeta inglês Wystan Hugh Auden. Drummond fez uma adaptação cenográfica do poema de W.H. Auden. As semelhanças entre os cenários são evidentes no uso dos seguintes expedientes: (a) o cenário de abertura do poema de Auden (no qual um andarilho caminha por uma estrada ou rua e se depara com uma visão maquinal e epifânica) é reutilizado por Drummond; (b) a atmosfera sombria e quase noturna da hora das Vésperas, acompanhada do badalar dos sinos da igreja ou do toque dos relógios, é comum em ambos os poemas; (c) a estrutura dialogal das máquinas que falam e desvelam mistérios é comum aos dois textos; (d) a narrativa escatológica do desfecho dos poemas é, também, muito similar. Concluímos que a semelhança entre os cenários dos dois poemas torna evidente as diferenças entre a perspectiva cristã do poema de W.H. Auden e a perspectiva absurdista do poema de Drummond.Palavras-Chave: A máquina do mundo; Carlos Drummond de Andrade; W.H. Auden; As I Walked Out One Evening.Abstract: Critics interpret the poem “A Máquina do Mundo,” by Carlos Drummond de Andrade, in regard to its use of intertextuality, as a poem marked by a subliminal dialogue with Dante Alighieri’s Divine Comedy and with Luís de Camões’s Os Lusíadas. In contrast to this repeated interpretation of the poem, I will try to demonstrate the hypothesis that the scenario of “A Máquina do Mundo” was built and imagined from a re-reading of the scenario of the poem “As I Walked Out One Evening,” by Wystan Hugh Auden. Drummond made a scenographic adaptation of the poem by W. H. Auden. The similarities between the scenarios are evident by use of the following devices: (a) the opening setting of Auden’s poem (in which a wanderer walks along a street and is faced with a mechanical and epiphanic vision) is reused by Drummond; (b) the dark and almost nocturnal atmosphere of Vespers, accompanied by the ringing of church bells or the chiming of clocks, is common to both poems; (c) the dialogical structure of the machines that speak and reveal mysteries is common to both texts; (d) the eschatological narrative at the denouement of the poems is also very similar. I conclude that the similarity between the scenarios of the two poems makes evident the differences between the Christian perspective of W.H. Auden’s poem and the absurdist perspective of Drummond’s poem.Keywords: A máquina do mundo; Carlos Drummond de Andrade; W.H. Auden; As I Walked Out One Evening.