bluuebunny/crossref_metadata_2025 huggingface dataset:
Liver ACSM3 deficiency mediates metabolic syndrome via a lauric acid-HNF4α-p38 MAPK axis
Authors: Xiao Xiao , Li Ruofei , Cui Bing , Lv Cheng , Zhang Yu , Zheng Jun , Hui Rutai , Wang Yibo
Published: January 2024

Metabolic syndrome combines major risk factors for cardiovascular disease, making deeper insight into its pathogenesis important. We here explore the mechanistic basis of metabolic syndrome by recruiting an essential patient cohort and performing extensive gene expression profiling. The mitochondrial fatty acid metabolism enzyme acyl-CoA synthetase medium-chain family member 3 (ACSM3) was identified to be significantly lower expressed in the peripheral blood of metabolic syndrome patients. In line, hepatic ACSM3 expression was decreased in mice with metabolic syndrome. Furthermore, Acsm3 knockout mice showed glucose and lipid metabolic abnormalities, and hepatic accumulation of the ACSM3 fatty acid substrate lauric acid. Acsm3 depletion markedly decreased mitochondrial function and stimulated signaling via the p38 MAPK pathway cascade. Consistently, Acsm3 knockout mouse exhibited abnormal mitochondrial morphology, decreased ATP contents, and enhanced ROS levels in their livers. Mechanistically, Acsm3 deficiency, and lauric acid accumulation activated nuclear receptor Hnf4α-p38 MAPK signaling. In line, the p38 inhibitor Adezmapimod effectively rescued the Acsm3 depletion phenotype. Together, these findings show that disease-associated loss of ACSM3 facilitates mitochondrial dysfunction via a lauric acid-HNF4a-p38 MAPK axis, suggesting a novel therapeutic vulnerability in systemic metabolic dysfunction.
Nasal bots carry relevant titers of CWD prions in naturally infected white-tailed deer
Authors: Soto Paulina , Bravo-Risi Francisca , Kramm Carlos , Gamez Nazaret , Benavente Rebeca , Bonilla Denise L , Reed J Hunter , Lockwood Mitch , Spraker Terry R , Nichols Tracy , Morales Rodrigo
Published: January 2024

Chronic wasting disease (CWD) is a prion disease affecting farmed and free-ranging cervids. CWD is rapidly expanding across North America and its mechanisms of transmission are not completely understood. Considering that cervids are commonly afflicted by nasal bot flies, we tested the potential of these parasites to transmit CWD. Parasites collected from naturally infected white-tailed deer were evaluated for their prion content using the protein misfolding cyclic amplification (PMCA) technology and bioassays. Here, we describe PMCA seeding activity in nasal bot larvae collected from naturally infected, nonclinical deer. These parasites efficiently infect CWD-susceptible mice in ways suggestive of high infectivity titers. To further mimic environmental transmission, bot larvae homogenates were mixed with soils, and plants were grown on them. We show that both soils and plants exposed to CWD-infected bot homogenates displayed seeding activity by PMCA. This is the first report describing prion infectivity in a naturally occurring deer parasite. Our data also demonstrate that CWD prions contained in nasal bots interact with environmental components and may be relevant for disease transmission.
BRD4 isoforms have distinct roles in tumour progression and metastasis in rhabdomyosarcoma
Authors: Das Dipanwita , Leung Jia Yu , Balamurugan Shivaranjani , Tergaonkar Vinay , Loh Amos Hong Pheng , Chiang Cheng-Ming , Taneja Reshma
Published: January 2024

BRD4, a bromodomain and extraterminal (BET) protein, is deregulated in multiple cancers and has emerged as a promising drug target. However, the function of the two main BRD4 isoforms (BRD4-L and BRD4-S) has not been analysed in parallel in most cancers. This complicates determining therapeutic efficacy of pan-BET inhibitors. In this study, using functional and transcriptomic analysis, we show that BRD-L and BRD4-S isoforms play distinct roles in fusion negative embryonal rhabdomyosarcoma. BRD4-L has an oncogenic role and inhibits myogenic differentiation, at least in part, by activating myostatin expression. Depletion of BRD4-L in vivo impairs tumour progression but does not impact metastasis. On the other hand, depletion of BRD4-S has no significant impact on tumour growth, but strikingly promotes metastasis in vivo. Interestingly, BRD4-S loss results in the enrichment of BRD4-L and RNA Polymerase II at integrin gene promoters resulting in their activation. In fusion positive alveolar rhabdomyosarcoma, BRD4-L is unrestricted in its oncogenic role, with no evident involvement of BRD4-S. Our work unveils isoform-specific functions of BRD4 in rhabdomyosarcoma.
A novel lateral flow immunochromatographic assay using a recombinant VP2 antigen for total antibody detection of canine parvovirus-2
Authors: Salmanli Ezgi , Tezcan Tugba , Karaoglu Taner
Published: January 2024

Expression of a recombinant VP2 antigen in E. coli and the process on a cLFA system for total antibody detection of canine parvovirus-2.
Evaluating Riboglow-FLIM probes for RNA sensing
Authors: Sarfraz Nadia , Shafik Luke K. , Stickelman Zachary R. , Shankar Uma , Moscoso Emilia , Braselmann Esther
Published: January 2024

The Riboglow platform has a small molecule fluorescence lifetime imaging microscopy (FLIM) sensor. Distinct cellular environments, like two different cell lines, lead to quantifiable FLIM differences.
Photo-thermal waxgels with fast wax layer regeneration ability for anti-icing
Authors: Wang Xiang , Zhang Lingling , Zhao Yuehua , Ren Huili , Liu Yiming , Ju Jie , Yao Xi
Published: January 2024

Waxgels are known to slowly regenerate wax peels spontaneously. Here, black carbon composite enables the photo-thermal-accelerated regrowth of sacrificial wax peel on waxgel surfaces for an on-demand de-icing operation.
Comparative study of epitaxial growth and Ni/GaN Schottky device on patterned sapphire substrates
Authors: Liang Zhiwen , Zhang Neng , Wang Fengge , Xu Yanyan , Yang Xien , Liang Yisheng , Li Xin , Liu Zenghui , Lin Lizhang , Zhang Baijun
Published: January 2024

GaN epitaxial materials and Ni/Au SBDs were fabricated and discussed on different patterned sapphire substrates. The reverse bias leakage is sensitive to screw dislocations, and the screw dislocations tend to form γ-type pits on concave PSS.
Theoretical prediction of donor–acceptor type novel complexes with strong noble gas–boron covalent bond
Authors: Kuntar Subrahmanya Prasad , Ghosh Ayan , Ghanty Tapan K.
Published: January 2024

Noble gas donor–acceptor type complexes with Ng–B covalent bonding! First ever report on very strong noble gas-boron (NgBNM+; Ng = He–Rn; M = H, Cu, Ag, Au) complexes with shortest Ng–B bond length, predicted through quantum chemical calculations.
A model analysis of centimeter-long electron transport in cable bacteria
Authors: van der Veen Jasper R. , Valianti Stephanie , van der Zant Herre S. J. , Blanter Yaroslav M. , Meysman Filip J. R.
Published: January 2024

Model analysis suggests that the conduction mechanism in cable bacteria is markedly distinct from other known forms of long-range biological electron transport, such as in multi-heme cytochromes.
Log-Gaussian gamma processes for training Bayesian neural networks in Raman and CARS spectroscopies
Authors: Härkönen Teemu , Vartiainen Erik M. , Lensu Lasse , Moores Matthew T. , Roininen Lassi
Published: January 2024

We propose an approach utilizing gamma-distributed random variables, coupled with log-Gaussian modeling, to generate synthetic datasets suitable for training neural networks.
First-principles prediction of ferroelectric Janus Si2XY (X/Y = S/Se/Te, X ≠ Y) monolayers with negative Poisson's ratios
Authors: Zhu Yunlai , Qu Zihan , Zhang Jishun , Wang Xiaoteng , Jiang Shuo , Xu Zuyu , Yang Fei , Wu Zuheng , Dai Yuehua
Published: January 2024

The discovery of novel ferroelectric Janus Si2XY (X/Y = S/Se/Te, X ≠ Y) monolayers with negative Poisson's ratios presents exciting prospects for various applications in nanomechanical, nanoelectronic and optoelectronic devices.
Borataalkenes, boraalkenes, and the η2-B,C coordination mode in coordination chemistry and catalysis
Authors: Eaton Maxwell , Zhang Yuanzhe , Liu Shih-Yuan
Published: January 2024

This review summarizes the recent advances in the synthesis of transition metal borataalkene and boraalkene complexes, and the η2-B,C coordination mode in homogeneous catalysis.
Automated quantum chemistry for estimating nucleophilicity and electrophilicity with applications to retrosynthesis and covalent inhibitors
Authors: Ree Nicolai , Göller Andreas H. , Jensen Jan H.
Published: January 2024

Reactivity scales such as nucleophilicity and electrophilicity are valuable tools for determining chemical reactivity and selectivity.
Machine learning interatomic potentials for amorphous zeolitic imidazolate frameworks
Authors: Castel Nicolas , André Dune , Edwards Connor , Evans Jack D. , Coudert François-Xavier
Published: January 2024

Accurate microscopic models of amorphous metal–organic frameworks (MOFs) are difficult to create. Machine learning potentials based on data from ab initio molecular dynamics offer a novel way to achieve this goal.
Development of carboxymethyl cellulose–chitosan based antibacterial films incorporating a Persicaria minor Huds. essential oil nanoemulsion
Authors: How Yu-Hsuan , Lim Emily Min-Yan , Kong Ianne , Kee Phei-Er , Pui Liew-Phing
Published: January 2024

As plastic waste has continued to increase over the years, there is an appeal for environmental-friendly packaging containing bioactive components such as essential oil for food packaging.
Electroreductive upgradation of biomass into high-value chemicals and energy-intensive biofuels
Authors: Wang Keping , Li Zheng , Guo Zhenyan , Huang Jinshu , Liu Tengyu , Zhou Min , Hu Jinguang , Li Hu
Published: January 2024

Recent advances in electroreductive upgradation of biomass to high-value chemicals and energy-intensive biofuels via various transformation routes are showcased.
SliceChip: a benchtop fluidic platform for organotypic culture and serial assessment of human and rodent pancreatic slices
Authors: Alver Charles G. , Álvarez-Cubela Silvia , Altilio Isabella , Hutchison Emily , Warrner Emma , Viso Mariana E. , Vitale Giana , Oliver David , Pastori Ricardo L. , Dominguez-Bendala Juan , Agarwal Ashutosh
Published: January 2024

SliceChip maintains perfusion, oxygenation, and bubble free operation for long term culture, imaging, assessment, and recovery of pancreatic slices.
Solid–gas synthesis of stable V3S4 nanoflakes: electrochemical characterization as a Li-ion battery anode
Authors: Madhuri Balla Rekha , Adigilli Harish Kumar , Karati Anirudha , Joardar Joydip , Vijay R. , Rao Tata Narasinga , Sahoo Ramkrishna
Published: January 2024

Low temperature synthesis of V3S4 nanoflakes using a unique gas–solid reaction route.
An aqueous rechargeable copper ammonium hybrid battery with good cycling performance
Authors: Yang Wenhui , Zhang Xikun , Shu Guangchang , Yu Haoxiang , Zhang Liyuan , Yan Lei , Shu Jie
Published: January 2024

This work assembles an aqueous rechargeable copper ammonium hybrid battery, which combines the merits of an NH4+-rich copper hexacyanoferrate (N-CuHCF) cathode and the high safety, high capacity, and abundant reserves of a Cu anode.
Copper nitrate-enabled ring expansion reaction of cyclopropanes: a direct approach to 3-cyano-isoxazoline N-oxides
Authors: Deng Yong , Yang Zhenkun , Li Yanze , Li Xinyao , Xu Bin
Published: January 2024

A novel copper nitrate-enabled ring expansion reaction of cyclopropanes with an unprecedented nitro and cyano group exchange process was reported, to afford pharmacologically interesting 3-cyano-isoxazoline N-oxides.
Sustainable artificial coral reef restoration using nanoclays and composite hydrogel microcapsules
Authors: Fahimizadeh Mohammad , Sukiato Febrianne , Chew Kok Lynn , Affendi Yang Amri , Pasbakhsh Pooria , Lee Tan Joash Ban , Raman R. K. Singh , Yuan Peng
Published: January 2024

Nanoclays, nanocomposite hydrogel microcapsules, and encapsulated bacteria can be considered as cement replacements for artificial coral reef development.
Synthesis of fine Na-type zeolite grains from coal fly ash and the assessment of the adsorption capability of lead ions from aqueous solutions
Authors: Ogata Fumihiko , Nagai Noriaki , Uematsu Yugo , Kobayashi Yuhei , Kitamura Nanako , Saenjum Chalermpong , Kawasaki Naohito
Published: January 2024

Fine Na-type zeolite grains (ZE) were prepared by dry milling treatment (D-ZE) or wet milling treatment (W-ZE).
Using spatial confinement to decipher polymorphism in the organic semiconductor p-DTS(FBTTh2)2
Authors: Marina Sara , Dyson Matthew , Rodríguez-Martínez Xabier , Reid Obadiah G. , Li Ruipeng , Rumbles Garry , Smilgies Detlef , Amassian Aram , Campoy-Quiles Mariano , Stingelin Natalie , Martín Jaime
Published: January 2024

Spatial confinement at the nanoscale is exploited to achieve specific polymorphs in the organic semiconductor p-DTS(FBTTh2)2. A new polymorph exhibiting higher charge-carrier mobility compared to previously reported crystal form is found.
Excellent comprehensive electrical properties in KNN-based ceramics via synergistic effects of structural flexibility and domain engineering
Authors: Li Hongjiang , Chen Ning , Xing Jie , Chen Hao , Tan Zhi , Mo Mingyue , Chen Qifan , Zhu Jianguo , Li Feng , Liu Zhenlong , Ouyang Weifeng , Zhu Huixiang
Published: January 2024

A large d33 value of 483 pC N−1 and a high TC of 302 °C can be simultaneously obtained in KNNT-BNZ-BFO/0.004 LiF ceramics. The prototype device of KNNT-BNZ-BFO/0.004 LiF buzzers is fabricated, and its SPL reaches 95–98 dB at 4–5 kHz.
Manganese dissolution in alkaline medium with and without concurrent oxygen evolution in LiMn2O4
Authors: Bisen Omeshwari Yadorao , Baumung Max , Tatzel Michael , Volkert Cynthia A. , Risch Marcel
Published: January 2024

Manganese oxides such as LiMn2O4 exhibit two distinct Mn dissolution processes; one independent of oxygen evolution and the other associated with it. Less Mn4+ before the onset of the OER lowers the Mn dissolution rate.
Black goes green: single-step solvent exchange for sol-gel synthesis of carbon spherogels as high-performance supercapacitor electrodes
Authors: Salihovic Miralem , Pameté Emmanuel , Arnold Stefanie , Sulejmani Irena , Bartschmid Theresa , Hüsing Nicola , Fritz-Popovski Gerhard , Dun Chaochao , Urban Jeffrey J. , Presser Volker , Elsaesser Michael S.
Published: January 2024

The novel synthesis of carbon spherogels in organic solvents enables energy and solvent savings and omits supercritical drying. In addition, the resulting carbon spherogels feature excellent capacitance for energy storage in a supercapacitor setup.
Multiple Range of Output Converter for Hazard Sensors with PV System
Authors: Aripriharta  , Firly Aprilia Putri Annisa , Omar Saodah , Wahyu Prasetyo Muchamad
Published: January 2024

Currently one of the renewable energy sources that is growing rapidly used a source of electricity from solar energy. Solar energy is converted into electrical energy through solar cell technology or photovoltaic. The proposed system designed a DC to DC converter to supply multiple outputs from the source of PV with an input value of 17VDC located on rural side supply an information of the temperature and humidity of a soil at the hill area near to a river. The converter able to produce multiple output of voltage within the given range.
Enhancing Measurement Quality of Voltage Divider Circuit and ACS712 DC Current Sensor in PPNS Baruna 01 Crewboat Solar Power Plant
Authors: Santoso Mardi , Putra Zindhu Maulana Ahmad , Nugraha Anggara Trisna , Najudah Faiqotin , Firdiansyah Rahmania
Published: January 2024

This research explores the crucial role of precise measurement in enhancing solar power generation efficiency within the maritime context, with a specific focus on the solar power plant aboard the PPNS Baruna 01 Crewboat. It investigates the relationship between light intensity and solar cell voltage output, affirming the direct correlation between sunlight availability and voltage generation. Additionally, the study introduces the application of simple linear regression techniques to improve measurement accuracy, particularly in voltage divider circuits and ACS712 current sensors. Results demonstrate a substantial reduction in measurement errors, from 34.88% to 0.45% for voltage measurement and from 23.71% to 2.69% for current measurement. These advancements hold significant implications for the maritime industry, promoting the adoption of clean and renewable solar energy sources on vessels, potentially reducing reliance on fossil fuels, and contributing to environmental sustainability. Moreover, the research underscores the importance of data analysis in optimizing energy systems and provides a foundation for further developments in renewable energy technology and system optimization.
Analysis of Energy Consumption for Hollow Structure of 3D Printed Part Reinforced by Polymer Resin
Authors: Bintara Redyarsa Dharma , Andoko  , Suprayitno  , Aji Pradana Yanuar Rohmat , Lai Jiing-Yih , Maulana Fiki , Yahya Haydar
Published: January 2024

Manufacturing time and energy consumption are two important parameters to evaluate the manufacturing process. The main purpose of this study was to analyze the energy consumption and printing time of 3D printed part between hollow and without any hollow structure. The specimen models were designed according to ASTM D368-IV standards and printed using a 3D printer device. During the printing process, the wall thickness of specimen was varied into three different types, 0.4 mm; 0.8 mm and 0.12 mm. Furthermore, the cavity was filled by polymer resin as main material for strengthening the specimen. Time and energy consumption of manufacturing process was recorded. In addition, the strength of specimens was observed using universal tensile test machine. The results showed that the highest manufacturing speed was occurred on the specimen that had wall thickness of 0.4 mm. Besides that, its parameter had a lowest energy consumption than specimen that had wall thickness 0.12 mm. The wall thickness showed the significant parameter to reduce the energy consumption, printing speed and material usage..
The Analysis of the Impact of Building Openings Design Variations on Thermal Comfort and Airflow Velocity by using CFD Simulation
Authors: Hajji Apif M. , Febriyanto Muh. , Alfianto Imam
Published: January 2024

Thermal comfort is very important to support a building’s user productivity. This study was conducted to investigate thermal comfort and airflow velocity in the engineering laboratory building at the State University of Malang.Preliminary observations have shown that the average room air temperature was around 27 - 31°C, which caused the uncomfortable condition. Thermal comfort enhancement in this study is investigated by applying several variations and treatments to existing openings. By using descriptive quantitative and experimental methods, the analysis uses the Computational Fluid Dynamics (CFD) simulation method with the ANSYS Workbench 19.0 Program. The simulation was applied to seven rooms with various types of openings. Parameters used in the simulation process are: 1) room geometry data consisting of images, room area, and location of ventilation openings, and 2) measurement reference points such as airflow velocity and room temperature. The dimensions of the openings will be observed by varying the treatment in each room, namely by opening all the inlets in the room (S), opening the inlets on the air vents only (J), and opening the inlets on the windows only (V). Primary data in the form of room temperature, airflow velocity, relative humidity, and physical dimensions of buildings are obtained through direct observation. The simulation results show that the maximum airflow velocity of the rooms (0.34 m/s) is found in the largest dimension variation of the inlet area of the opening (13.15 m2). The lowest temperature is found in the rooms with the smallest dimension of inlet (28oC) with the value of room temperature in the range of 27.5oC – 30.2°C. The statistical analysis of one-way ANOVA shows that by using a significance level of 0.05, there is an effect of variations in the design of openings on the level of thermal comfort in each room.
Development of Autodesk-based Digital Teaching Materials as a Support for Basic Digital Engineering Learning in Vocational Schools
Authors: Nur Handayani Anik , Nur Fitrianti Nabila , Kusumawardana Arya , Elmunsyah Hakkun , Arai Kohei , Andrie Asmara Rosa
Published: January 2024

This study aims to design and develop teaching materials for Basic Digital Engineering material in the Basics of Electronics Engineering Subject at the Mechatronics Department of SMKN 4 Malang. Obstacles in learning Basic Digital Engineering, lack of practicum facilities and learning resources, encourage the development of digital teaching materials as a structured solution. Autodesk Tinkercad platform is used to support offline practicum implementation. The purpose of using Autodesk-based learning to encourage students to collaborate and continue to carry out practicum independently outside the school environment. This research includes the development of job sheets consisting of teacher’s handbook and student’s handbook, covering basic logic gates, advanced logic gates, and introduction to microcontrollers. In addition, a guidebook was also developed to optimize the use of Autodesk Tinkercad. This research involves testing the feasibility of job sheets and guidebooks in learning Basic Digital Engineering Materials using the Autodesk Tinkercad platform. The results of this study can contribute to improving the quality of learning and conclude that the use of digital teaching materials with the support of Autodesk Tinkercad can increase student independence in Basic Digital Engineering Materials.
Development of Interactive Virtual Laboratory Media with Tinkercad Platform on Analog Electronics Material
Authors: Nur Handayani Anik , Sonia Nafista Salsabila , Kusumawardana Arya , Elmunsyah Hakkun , Arai Kohei , Andrie Asmara Rosa
Published: January 2024

The development of science and technology has experienced rapid progress which has a significant impact on people’s lives. One of the affected fields is education, where the utilization of science and technology can strengthen the learning process. In this context, the development of the right strategy and the use of supporting components are very effective. This research aims to analyze and develop the needs of teaching materials in the subject of Fundamentals of Electronic Engineering, focusing on Analog Electronics material. The method used is the development of teaching materials in the form of V-Lab-based jobsheets using the tinkercad website platform, as well as the preparation of guidebooks for teachers and students of Mechatronics Engineering in the subject of Basics of Electronics Engineering, especially on Analog Electronics material. Furthermore, the feasibility of V-Lab-based teaching materials using the Tinkercad website platform was tested. The results show that the use of the Tinkercad platform makes it easy to simulate electronic circuits without the need to install additional software. This platform helps students in better understanding the analog electronics material, as it can be accessed flexibly. Based on these findings, it can be concluded that the development of V-Lab-based teaching materials through the Tinkercad platform has great potential in improving the quality of analog electronics learning.
Influence of a magnetic field on the structure and electrical strength of polystyrene
Authors: Rustamova D. , Mayilov R. , Mehdiyeva A. , Mahmudova Z. , Bakhshaliyeva S.
Published: January 2024

The mechanism of action of the H field will be different depending on whether the polymer is in a molten form, or in the form of a solution under highly elastic conditions. The H-effect of spin-dependent reactions that, it can take place in a polymer as the main mechanism of the action of a magnetic field should be clearly felt. Our results confirm this. It is proved (by experiments) that the effect of a magnetic field on composites obtained by crystallization from a solution or a molten substance directly in a constant magnetic field can lead to the expected results.
Numerical and analytical method of calculation of dynamic strength of modernized air springs for high-speed electric trains
Authors: Khromova Galina , Makhamadalieva Malika
Published: January 2024

The article presents a new design of a pneumatic suspension device for the high-speed electric train “AFROSIAB”, Uzbekistan. The authors developed a numerical-analytical method for the calculation of dynamic strength of modernized pneumatic springs for high-speed electric trains; an algorithm and a program for the Mathcad 15 programming environment were built. The design given in the article is protected by the Patent of the Republic of Uzbekistan for invention No. IAP 04632 [1].
Renewable energy sources: global implementation experience
Authors: Nazarov Anton , Sulimin Vladimir , Shvedov Vladislav
Published: January 2024

The imperative transition towards renewable energy sources is a global challenge with diverse implementation experiences. This paper provides a comprehensive review of the worldwide deployment of renewable energies, examining case studies from different geographic and economic contexts to assess methods, outcomes, and lessons learned. It delves into the advancements in solar, wind, hydroelectric, and geothermal energy, showcasing innovative technologies and strategies that have significantly contributed to the energy mix. We analyze policy frameworks, investment patterns, and community engagement practices that have facilitated the adoption of renewables. Additionally, the paper explores the barriers to implementation, including economic, technical, and political challenges, and suggests pathways for overcoming these hurdles. Comparative analysis of the effectiveness of different renewable projects highlights the importance of tailored approaches that consider local conditions. The paper concludes with strategic recommendations for policymakers, industry stakeholders, and researchers to promote the global expansion of renewable energy sources, aiming for sustainability and energy security.
Energy-technological complex of Kalina cycle for seawater desalination
Authors: Prikhodko Yuri , Tarasova Tatyana , Bolkov Yaroslav
Published: January 2024

A scheme has been developed for the use of low-potential energy for heating water, including for the purpose of desalination of sea water. An assessment of the effectiveness of the Kalina cycle is given. It is proposed to use heated water in the water treatment cycle. This cycle can be implemented on geothermal sources near the ocean. Installations based on renewable energy sources fit into the country’s economy in an environmentally friendly way, and also increase energy security. Thus, the cycle is integrated into the seawater desalination system. However, there are some disadvantages to using geothermal energy. First, it is only available in certain parts of the world, since geologically active areas are required to access heat. In addition, installing the necessary equipment and infrastructure can be costly, making it difficult for some people to access this form of energy. Finally, the heat removal process can also lead to environmental degradation as it can harm sensitive ecosystems and water sources in the area.
Kyshtyrlinsk deposit clay properties research
Authors: Pavlova I.A. , Getman A.A. , Farafontova E.P.
Published: January 2024

The paper is devoted to study technological properties of low-melting clay. Research methods of clay properties that affect the technology of ceramic brick production are presented. The clay sample under study is an acid clay of montmorillonite mineral composition, medium plastic, with a low content of coarse inclusions and refers to low-disperse raw materials. A clay sample contains a low content of water-soluble salts, a low content of carbonate inclusions, and a low content (less than 1%) of coarse-grained inclusions. The clay is medium-drying, medium-sensitive to drying, non-sintering; after firing, it has high mechanical strength. Based on this clay, it is possible to produce common and face bricks with a strength of more than 10 MPa when using the plastic method of molding and firing in the range of 850–1050°C. Obtaining clinker brick requires refinement of the production technology by introducing sintering additives, since at this stage of project products are obtained with lower strength and high water absorption.
Competence “Engineering design” – a platform for developing the skills of designing an object of capital construction
Authors: Agaev T.G. , Chumanov A.A. , Silin V.E. , Koshkarov A.A. , Volodin A.M.
Published: January 2024

The construction industry is undergoing a change in approaches to the design of capital construction projects due to the preparation of consolidated digital models in the course of designing and working with the information placed therein. This requires updating the content and changing the format of training students in the fields of study and specialties related to the design of capital construction projects and their engineering systems. Based on the comparison of the current format of training engineering students to the format of professional activities of engineers involved in the design of capital construction projects, it is shown that today’s training system does not fully take into account the specifics of team work of engineers of various profiles in the course of project development. The necessity of using methods of cross-discipline team training is substantiated. It is proposed to use the best practices in competence R94 “Engineering Design” of the WorldSkills Russia “Young Professionals” national championship as a methodological basis for organizing such training format.
Assessment of effectiveness of implementation of BIM technology in the system of an organization management on the example of an energy efficiency formula
Authors: Pridvizhkin Stanislav , Ilyushin Artyom
Published: January 2024

This article examines the degree of study of the methodological foundations of BIM technology. A generalization of the BIM technology features for the main stages of the life cycle is given. The aspects of information modeling (BIM) technology implementation are considered. One of the possible methods for evaluating the decision effectiveness in the process of introducing BIM technology is proposed using the energy efficiency formula as an example.
Esg - company rating as a pass to a smart city
Authors: Medvedeva Elizaveta , Shklyaeva Victoria , Shalneva Maria
Published: January 2024

This article discusses the results of the study reflecting the mechanism of evaluation of companies to enter the system of Smart Cities, based on a generalized indicator of ESG-rating, which will identify companies that comply with the principles of sustainable development and their entry into the system of Smart Cities will lead to accelerated development of the entire system.
Prerequisites for developing the computer vision system for drowning detection
Authors: Kozlov Eduard , Gibadullin Ruslan
Published: January 2024

The problem of drowning is one of the most serious issues in terms of human life and health safety. Drowning victims often fall victim to accidental circumstances or unintentional actions, and the number of such incidents is significant. Thousands of drownings occur worldwide every year, resulting in a significant loss of lives, both among adults and children. This article focuses on exploring the prerequisites and developing a computer vision system for drowning detection. Drowning is a serious problem that poses substantial social, economic, and medical consequences for human life and health. The article discusses key computer vision technologies, image processing algorithms, and object recognition methods.
Development of an information system for determining the opinion of citizens based on analysis of information on social networks and mass media
Authors: Nikolaeva D.R. , Nikolenko T.A. , Sidorov D.
Published: January 2024

Currently, most of the modern society is concentrated in large and medium-sized cities. This gives residents more opportunities for self-realization, professional development, socialization, as well as a greater number of options for spending their personal time, which undoubtedly affects the satisfaction of a person living in an urban environment. To prevent a decline in the development of the city, constant monitoring of the state of the urban environment is necessary, since the population is constantly in direct contact with it. The number of the city's population and the satisfaction of living in it is one of the most important components of the indicator of the development of all sectors of the city. Assessment of the mood of the population is most often done through personal interviews with citizens. The purpose of the survey is to get an opinion about the general situation in the city or about certain areas, events, news. To automate this process, it was decided to create an information system for collecting citizens' opinions on certain events in social networks and mass media, which greatly simplifies the process of assessing the mood of citizens.
Application of information modelling technologies to avoid typical mistakes in the design of constructive solutions
Authors: Serbin S. , Fomin N. , Seregina N.
Published: January 2024

The use of information modelling technologies is spreading more and more in the construction industry. A large number of construction projects with budget financing require state expertise. The potential for automating the verification of structural solutions for design documentation has not been fully disclosed to date. The authors of the article analyzed the comments of the expert of the constructive department of the state expertise over the past 2 years and identified a list of the most common ones. Based on this, proposals were formulated for the formation of digital information models of the structural solutions in order to automate the processes of checking design solutions and avoid similar mistakes in the future.
Comprehensive integration of the interaction of ecology, science and education in the context of the scientific and technological revolution and the formation of a sustainable society
Authors: Zinchenko Viktor , Abasov Mir Faraj Ali , Polishchuk Oleksandr , Polishchuk Olena , Levkulych Vasyl , Lazarovych Mykola , Tryma Kateryna
Published: January 2024

Taking into account the modern ecological problems accumulated by mankind since the times of antiquity, the article draws attention to the peculiarities of the worldview, and its change, and defines the peculiarities of the philosophy of ecology in the society of sustainable development. In the process of research, the essence and significance of the philosophy of ecology as a direction of philosophical research that forms the basis of worldview orientations was clarified, and by resorting to praxeology, it was possible to reveal the potential opportunities of education in the ecological thinking of the future self. The features of the socio-anthropological awareness of the need for the concept of sustainable development are considered and the philosophy of ecology is in the process of environmentalization of public consciousness. For a better understanding of the need for environmental awareness in society, an important role was played by international concepts and regulatory legal acts, which are the basis of the research and writing of the article itself. They became one of the reasons for the rethinking of the self-based on the ecological tasks in the society of sustainable development. In this context, special attention is paid to education, a social institution, one of the main tasks of which is the formation of the future self by instilling value orientations and the awareness that a person is a part of nature, which at the same time is his home. However, any changes cannot occur without a change in the consciousness of the Self, and in this case, the leading role is given to the philosophy of ecology as a part of philosophical knowledge whose task is to form an ecological worldview.
Soil gamasina mites (Acari: Gamasina) as components of biocenoses under arid conditions
Authors: Khydyrov Peyzulla
Published: January 2024

The results of research conducted in the period 2002–2004 and 2019–2022 on the study of the ecology of gamasid mites living on biocenoses of cotton, wheat and melons in the northern regions of Turkmenistan are presented. In particular, 10 species of gamasid mites were identified in the listed biocenoses, including 3 new species for the fauna of the country. According to the selectivity of ecological niches, the discovered mites are classified as eurybionts and geophyllobionts. The importance of predatory gamasid mites in biocenoses is shown in regulating the number of herbivorous mites. Some insects and nematodes, the role of gamasid mites as the main component in the biocenosis, which ensures the functioning of the predator-prey relationship, is proved. Laboratory observations revealed the specificity of the choice of prey by predatory mites in the species B. tarsalis, Ph. plumifer and N. bicaudus. The specifics of the choice of prey by the tick Ph. plumifer in the laboratory in the optimum temperature range of +20 – +25°C and a humidity degree of 40-65%. They actively bred on tea rose leaves when C. pulcher was used as a mite victim. The results of observations under a stereomicroscope on the study of the ethological characteristics of the predatory mite N. bicaudus during its attack on its prey in the leaves of an apple tree are also presented. Researches have revealed the specificity of the choice of the herbivorous mite Siteroptes tameri by the predatory mite N. bicaudus as a prey. The active role of the latter in the spread of spores of the fungus N. gossypii has also been proven. Field observations revealed that predatory mites G. aculeifer, B. tarsalis and N. bicaudus feed on herbivorous mites in biocenoses. For predators, specific types of prey have been established, related to spider mites, acaroid and eriophyid mites. The role of gamasid mites in establishing the ecological balance of herbivorous mites in biocenoses has been proved.
Effect of external air temperature on buildings and structures and monuments
Authors: Nabiyev Mominjon , Salimov Orif , Khotamov Asadulla , Akhmedov Tolqin , Nasriddinov Khasan , Abdurakhmanov Ulugbek , Raximov Rasuljon , Khalimov Abbosbek , Abobakirov Azizbek
Published: January 2024

The article provides information about external factors affecting the migration of residential and public buildings and architectural monuments.
Wind farms in agro industry: stabilization of turbine blade operation during wind gusts
Authors: Osintsev Konstantin , Mamazhonov Abdulaziz , Sobol’kin Sergey
Published: January 2024

This article is dedicated to the topic of wind farms in the context of agro-industry, with a particular focus on stabilizing the operation of wind turbine blades during gusts of wind. The article analyzes various approaches to blade control in case of sudden changes in wind speed, including the use of advanced control algorithms and the integration of backup power supply systems. The results of the study indicate that advanced control algorithms can significantly improve the stability of wind turbine operation in wind gusts, reducing the need for emergency shutdowns and backup power supply, making wind energy a more competitive source of renewable energy. The article highlights the importance of further research and innovation in wind turbine technology, particularly in the areas of blade control and backup power supply, to ensure a reliable and sustainable source of clean energy in the future.
The impact assessment of automated drip infusion control using weighing scale and pinch method on subjects
Authors: Agustine Lanny , Astarini Made Indra Ayu , Manungkalit Maria , Amadeus Jose , Pranjoto Hartono
Published: January 2024

A novel approach in infusion flow control technology under development is based on liquid weight and pinch valve control to stop and control the flow for better management. The main part of this device consists of a load cell, a microcontroller, and a pinch valve. In this method, a pinch valve controls the rate of infusion drops as prescribed to the patient, so that nurses do not have to keep on checking the infusion flow rate. The device detects the infusion flow from the measured liquid weight, which is mathematically converted to volume. A pinch valve, via a pinch-release method, controls the amount of fluid via the pinch duration. In this study, the effective duration of valve opening and the sensations of the fluid flow by the patients are also studied. The study, which involves fourteen healthy subjects, shows that a valve opening of a maximum of 70 ms is still considered comfortable. Some subjects indicate discomfort with pinch opening longer than 70ms. A valve opening of less than 70ms shows no significant impact on the increase of outflow volume with a pinch-release period of 3000ms. The increase in outflow volume is quite linear concerning the pinch valve opening period. With this method, the prescription is more accurate and will lessen the impact of medical waste for better environmental impact..
Distribution model, depositional environment and facies of coal in the AE field, Kutai Kartanegara area, East Kalimantan
Authors: Sutedjo Taufiq Erlangga , Pambudi Setyo , Listyani R.A.T. , Sugarbo Oky
Published: January 2024

The AE field is a planned coal mining area in Kutai Kartanegara, East Kalimantan. A preliminary analysis of coal and non-coal lithology conditions, which act as constituents of the AE Field, must be carried out to determine the next step in the mining business. The physical properties of several coal seams in the AE Field are different, so characterization is necessary. The purpose of this study is to characterize coal and non-coal lithology in the study area, while the aim is to determine the facies analysis and depositional environment of coal. The research method used is surface and subsurface mapping (drilling). The results showed that the AE Field has four coal seams, namely seams-1, 2, 3, 4A, and 4B, which dip to the northeast. The coal formed in the lower delta plain transitional depositional environment, in the swamp, crevasse splay, channel, levee, and inter-distributary bay facies.
Fast fashion revolution: Unveiling the path to sustainable style in the era of fast fashion
Authors: Anisah Tiara Nur , Andika Andika , Wahyudi Danang , Harnaji Bimo
Published: January 2024

The Fast fashion industry trend has proliferated due to its fast production and affordable prices. However, its negative impact on the climate and environment is significant. Previous research has revealed that Fast Fashion contributes to high greenhouse gas emissions, excessive water usage, water pollution, and the generation of non-biodegradable textile waste. All of these factors harm environmental sustainability. Additionally, the mass production model of Fast Fashion also encourages excessive consumption, creates non-biodegradable textile waste, and increases pressure on natural resources. This study aims to examine the relationship between fashion orientation (FO) and Fast fashion purchase intention (FFPI), as well as their impact on Fast fashion purchasing behavior (FFPB). This research also explores the influence of sustainable clothing consumption attitudes (SCCA) as a moderating factor. Data were collected from 214 respondents through the nonprobability snowball sampling method. The analysis was conducted using the PLS-SEM method. The study's results indicate that FO significantly influences FFPI and strongly correlates with FFPB. Moreover, SCCA moderates the relationship between FFPI and FFPB. These findings imply that to address the negative impact of Fast Fashion on climate change and the environment, changes in FO and FFPI and an increase in SCCA are needed. Education and consumer awareness regarding the negative impacts of Fast Fashion, promotion and support for sustainable clothing brands and products, and implementing policies that encourage more sustainable production and consumption practices are essential steps that can be taken.
Development of digital livestock monitoring in Sambilawang Village, Serang, Banten
Authors: Kikitamara Sesaria , Mujahidah Izzahtul , Rizky Permata Nur Miftahul
Published: January 2024

The stockbreeders in Sambilawang Village face challenges in managing their livestock using traditional methods, resulting in inefficiencies and potential income losses. This study aims to develop a mobile application-based monitoring system to enhance livestock management for stockbreeders in Sambilawang Village while fostering collaboration with potential investors. The proposed system is designed to offer an interactive digital platform that enables stockbreeders to monitor livestock growth, health, and condition efficiently. Notifications will be implemented to inform both stockbreeders and investors about key events such as readiness for sale, breeding, or milking, simplifying the process of buying and selling livestock. The implementation of the digital monitoring platform significantly improves the management of livestock in Sambilawang Village. Stockbreeders can now maintain accurate records and provide timely updates to potential investors, enhancing their income and facilitating collaboration with buyers. The application also streamlines the livestock sales process, reducing disruptions in meat distribution. In conclusion, the development of this mobile application-based monitoring system represents a crucial step in addressing the challenges faced by stockbreeders in Sambilawang Village. By promoting efficient livestock management and fostering collaboration with investors, this solution has the potential to stabilize the stockbreeding profession and benefit the entire community.
Key determinant of visitors' environmentally responsible behavior at Mlarangan Asri Beach Kulon Progo Regency, Indonesia
Authors: Hasanah Erni Ummi , MZ Yumarlin , Lantarsih Retno , Ardi Iwan Aminto , Wahyudi Danang , Andika  , Luthfiana Della Nanda
Published: January 2024

The sustainability of tourist attractions can be enhanced through Environmentally Responsible Behavior (ERB). This study aims to identify key factors that encourage visitor to ERB at Mlarangan Asri Beach and to explore the mechanisms of their impact. We surveyed 157 visitors at Mlarangan Asri Beach in Kulon Progo. Our findings, based on structural equation modeling, indicate that personality traits significantly and positively affect both environmentally responsible behavior and visitor satisfaction. However, visitor satisfaction does not influence environmentally responsible behavior, nor does it mediate the impact of personality traits on ERB. The study reveals that the primary determinant of ERB at Mlarangan Asri Beach is personality traits, comprising five indicators: neuroticism, agreeableness, conscientiousness, openness to experience, and extraversion.