bluuebunny/crossref_metadata_2025 huggingface dataset:
Sustainable Approaches to Boost Yield and Chemical Constituents of Aromatic
and Medicinal Plants by Application of Biostimulants
Authors: Shahrajabian Mohamad Hesam , Sun Wenli
Published: October 2022

Introduction:

Biostimulants consist of natural ingredients, metabolites of fermentation,
micro-organisms, algae or plant extracts, bacteria, mushrooms, humus substances, amino
acids, biomolecules, etc.

Methods:

In this study, all relevant English-language articles were collected. The literature was
reviewed using the keywords of biostimulant, medicinal plant, aromatic plant, natural products,
and pharmaceutical benefits from Google Scholar, Scopus, and PubMed databases.

Results:

The significant and promoting impact of biostimulants has been reported for different
medicinal and aromatic plants, such as salicylic acid for ajuga, artichoke, ajwain, basil, common
rue, common sage, common thyme, coneflower, coriander, dendrobium, desert Indian wheat,
dragonhead, fennel, fenugreek, feverfew, ginger, groundnut, guava, henna, Iranian soda, lavender,
lemon balm, lemongrass, Malabar spinach; seaweed extract on almond, bird,s eye chili; amino
acids on artemisia, broccoli, chamomile, beneficial bacteria on ashwagandha; humic acid on
black cumin, cannabis, chicory, garlic, gerbera, Hungarian vetch, Moldavian dragonhead, niger
plant; chitosan on dragon fruit, marigold, milk thistle, etc. The suggested mechanisms include the
stimulatory impacts on the activity of enzymes involved in different biosynthetic processes, the
hormone-like activity of biostimulant compounds and the improvement of nutrient uptake of
plants.

Conclusion:

The current manuscript gives many examples of the potential of biostimulants for
medicinal and aromatic plant production. However, further studies are needed to better understand
the effectiveness of different biostimulants and foliar applications in sustainable agriculture.
COVID-19 vaccine hesitancy and response to a simple educational intervention in patients attending an outpatient dialysis unit in Johannesburg, South Africa
Authors: Cassimjee Zaheera , Davies Malcolm , Dayal Chandni , Chiba Sheetal
Published: October 2022

Background: Patients living with kidney failure are at risk of severe COVID-19 disease. However, vaccination reduces transmission and severity of disease. The uptake of COVID-19 vaccination in South Africa remains poor, suggesting a requirement for novel recruitment strategies. We examined COVID-19 vaccine hesitancy in an urban dialysis population in Johannesburg, South Africa, and investigated the efficacy of an educational intervention on vaccination intention. Methods: One hundred and four participants were recruited from outpatient haemo- and peritoneal dialysis units at the Helen Joseph Hospital. Participants completed anonymous, self-administered questionnaires analysing their acceptance of and concerns regarding COVID-19 vaccination before and after dissemination of the South African Nephrology Society SARS-CoV-2 vaccine information brochure. Results: Seventy-two participants (69%) were unvaccinated against SARS-CoV-2; 23 (22%) indicated unwillingness to undergo vaccination. Vaccine side effects, safety and perceived risk of SARS-CoV-2 transmission by vaccination were important factors in hesitancy. A small proportion believed that COVID-19 was not a serious threat to personal health. News media was an important information source for vaccine-hesitant respondents; prior healthcare worker counselling reduced hesitancy (OR 0.175, 95% CI 0.039–0.784; P = 0.023). The information brochure reduced concerns about vaccine side effects (P = 0.028), increasing vaccination intention to 84%. In-centre vaccination was additionally identified as a strategy to reduce hesitancy (OR 0.053, 95% CI 0.012–0.221; P < 0.001). Conclusions: This first analysis in an urban dialysis population in South Africa highlights factors contributing to vaccine hesitancy. Simple educational interventions capitalising on trust in healthcare workers and improved vaccine accessibility may increase vaccine uptake. Keywords: COVID-19, vaccine hesitancy, dialysis
Vitamin D status and serum vitamin D binding protein levels in Nigerian children with nephrotic syndrome
Authors: Solarin Adaobi U , Adekunle Motunrayo O , Oladimeji Alaba B , Olutekunbi Olanike A , Lamina Moriam O , Oshomah-Bello Oluwatosin E , Adetola Olamide I , Animasahun Barakat A , Njokanma Olisaemedua F
Published: October 2022

Introduction: Nephrotic syndrome is a chronic relapsing condition associated with urinary loss of albumin and other proteins such as vitamin D binding protein (DBP). We determined vitamin D status and serum DBP levels in children with nephrotic syndrome and compared them to healthy controls. Methods: A cross-sectional study was performed over a six-month period in children less than 18 years of age. The children with nephrotic syndrome were categorised by disease status as either newly diagnosed, in remission, resistant to therapy, or in relapse. Vitamin D levels were regarded as sufficient if ≥75 nmol/L, insufficient if <75 nmol/L but ≥50 nmol/L, deficient if <50 nmol/L, and severely deficient if <25 nmol/L. Serum DBP was also measured. Results: Fifty-five children with nephrotic syndrome and 24 controls were included in the study. There was no significant difference between the median ages of the cases (72.0 months, interquartile range (IQR) 48.0–120.0 months) and the controls (84.0 months, IQR 39.0–129.0 months). Severe vitamin D deficiency, deficiency and insufficient levels were documented in 54.5%, 41.8% and 3.6% of cases, respectively, significantly lower than the controls (P = 0.003). Vitamin D levels were higher in children with nephrotic syndrome in remission than in those who were not (30.3 ± 15.2 nmol/L vs 19.6 ± 11.0 nmol/L, P = 0.004). In the groups who were in remission, newly diagnosed, relapsing, and resistant, the median vitamin D levels were 30.3 nmol/L, 20.1 nmol/L, 19.2 nmol/L and 9.4 nmol/L, respectively (P = 0.031). Conclusions: Hypovitaminosis D occurs frequently in Nigerian children with nephrotic syndrome as well as in apparently healthy controls. Routine supplementation of vitamin D should be considered in children with nephrotic syndrome irrespective of whether the disease is in remission or not, or whether it is steroid-sensitive or not. Keywords: nephrotic syndrome, vitamin D deficiency, vitamin D binding protein
South African Renal Registry Annual Report 2020
Authors: Davids M Razeen , Jardine Thabiet , Marais Nicola , Sebastian Sajith , Jacobs Julian
Published: October 2022

The ninth annual report of the South African Renal Registry summarises the December 2020 data on kidney replacement therapy (KRT) for patients with kidney failure in South Africa. The numbers of patients reported here are substantially lower than those recorded in the previous report. This is likely the result of several factors, including larger numbers of deaths from COVID-19 and other causes, delayed initiation of KRT due to the pandemic, and challenges with data submission to the registry during a period when personnel were overwhelmed with clinical responsibilities related to the pandemic. In December 2020, the number of patients who were being treated with chronic dialysis or transplantation stood at 8 734, a prevalence of 146 per million population (pmp). The prevalence of South Africans accessing treatment in the private healthcare sector was 729 pmp, whereas it was 44 pmp in the chronically under-resourced public sector, well below the rate reported for 1994.
Does opportunity to learn explain the math score gap between madrasah and non-madrasah students in Indonesia?
Authors: Umar Ahmad , Kusaeri Kusaeri , Ridho Ali , Yusuf Ahmad , Asyhar Ahmad Hanif
Published: October 2022

The opportunity to learn (OTL) is one of the important aspects of achieving the goal of the learning process. There have been three dimensions of OTL: instructional time (IT), content covered during instruction (CC), and quality of instruction (QI) mentioned in the literature and used as a framework in this article. This study aims to reveal the gap in math ability between madrasah and non-madrasah students in Indonesia and the contribution of the three OTL aspects toward math scores. This study employed a cross-sectional survey approach with self-report instruments. The data were obtained from a survey of participants in the New Students National Selection for Madrasah Aliyah Negeri (Islamic High-school managed by the ministry of religious affairs) in 2021. There were 8,258 participants, consisting of 4,842 students from madrasah and 3,416 from non-madrasah. This study used multilevel structural equation modeling (SEM) to analyze the data. The findings show that (a) there is a gap in math ability score between madrasah and non-madrasah students which is -27, with a mean math ability score of madrasah students being lower than non- madrasah students, and (b) the time invested in learning significantly affects the occurrence of gaps in math ability scores, while the scope of the materials and the quality of learning do not affect the occurrence of the gap in math ability scores. These findings suggest that it is important for the Ministry of Religious Affairs to consider the addition of mathematical lesson duration in madrasah while restructuring the allocation for Islamic lessons.
The effect of mother's burden on learning from home, maternal-efficacy, and maternal care practices on emotion and negative behavior of children aged 5-6 years
Authors: Rahmawati Devi , Hastuti Dwi , Simanjuntak Megawati
Published: October 2022

Mothers play a big role in every aspect of their children’s lives. During learning from home (LfH) period, children's negative behavior can also change and is influenced by maternal-efficacy, maternal burden, and parenting practices. The purpose of this study was to analyze differences in maternal burden and parenting practices before and during LfH and to analyze the effect of mothers' burden on learning from home, maternal-efficacy, and parenting practices on the negative behavior of children aged 5-6 years. This study used a cross-sectional and retrospective study design. This research was conducted in three kindergartens with an A accreditation status in Jagakarsa Village, Jagakarsa District, South Jakarta City, DKI Jakarta Province. The study involved 100 working mothers who were selected using non-probability sampling with a voluntary sampling technique. The results of the influence test showed that the mother's burden during LfH period had a significant negative effect on the mother's maternal efficacy, while the mother's maternal efficacy had a significant positive effect on negative parenting practices and negative child behavior. Based on the research results, the maternal-efficacy of parents was assumed to be not strong enough to prevent negative parenting practices carried out by parents during the Covid-19 pandemic. Furthermore, negative parenting practices by mothers had a significant positive effect on children's negative behavior.
Knowledge, attitudes, and behaviors of teachers and students toward sustainable development of Pili (Canarium ovatum)
Authors: Funa Aaron Aytona , Gabay Renz Alvin Emberga , Ibardaloza Rosel T. , Limjap Auxencia Alarcon
Published: October 2022

The urgent call by UNESCO to scale up interventions for the achievement of sustainable development goals motivated this study to assess the level and association of teachers' (n =107) and students' (n = 342) knowledge, attitudes, and behaviors (KAB) regarding education for sustainable development, focusing on Pili (Canarium ovatum). This is a subset of a larger project that involves Pili to contextualize learning and instructional materials. The researchers used a descriptive cross-sectional survey approach and distributed a questionnaire through Google Forms. KAB levels were categorized into poor, moderate, and high using descriptive data analysis and determined their association with one another using Pearson's Chi-square. The findings indicate that, although the associations among the KAB of teachers are distinct from those of the students, they both perceived that possessing favorable knowledge and attitudes are insufficient to generate positive behaviors. Thus, efforts to increase teachers' and students' motivation and involvement and to help them carry out favorable behaviors toward sustainable development are imperative. Given this, identifying the barriers to converting knowledge and attitudes into behaviors and considering the factors that involve the association of KAB in promoting sustainable development, particularly in education, are recommended.
The importance of learner-centered approach in vocabulary development
Authors: Mamatkulova Nilufar Fayzullakulovna , Fayzulla kizi Mamatkulova Nodira
Published: October 2022

This research article discusses opportunities to develop lexical competencies in learning English with the students of higher education institutions specialized in language based on a learner-centered approach. Pedagogical experiment was conducted at three higher education institutions in Uzbekistan: Jizzakh State Pedagogical Institute, Termez State University, Uzbekistan State University of World Languages with the 1st and 2nd year of the bachelor's degree. 463 students from the three higher education institutions participated in experiment. At the first point the study used a questionnaire developed by the author to collect information about the approaches of students in the process of language learning at universities in Uzbekistan. The survey helped to determine the extent to which students in all groups developed autonomous, independent learning skills and the formation of self-critical assessment skills. The averages collected through the survey were analyzed using inferential statistical methods. Students in the experimental group used lesson plans developed by the author during the academic year. According to the results of the study, the statistical analysis showed that the experimental work carried out to determine the level of effectiveness of the experiment was effective.
Focused classroom meeting model of teaching for enhancing students’ achievement motivation
Authors: Purwanto Edy , Sunawan Sunawan
Published: October 2022

There have been different models of achievement motivation models proposed in the literature. This article aims to examine the effectiveness of the Focused Classroom Meeting Model of Teaching (FCMMT) which is based on the Trisula Model of Achievement Motivation in English as a foreign language setting. The effectiveness of FCMMT was examined through experimental research with randomized pre-test post-test control group design. The subjects consisted of 40 students of 11th Grade who were randomly selected from a senior high school. They were, then, randomly assigned into two different groups, namely experimental and control groups. The experimental group received FCMMT of teaching model intervention, while the control group was given classroom management intervention by applying the experimental design of the control group pre-test multiple post-tests. Both experimental and control groups received teaching intervention for 12 sessions (90 minutes per session; twice per week). The achievement motivation scale used was adapted from the Motivated Strategies for Learning Questionnaire (MSLQ). The result of the experiment showed that FCMMT was effective in enhancing students’ achievement motivation. This study provides an alternative new model empirically found effective for increasing student achievement motivation, namely task value, self-efficacy, and goal orientation.
Profile of Students’ Science Process Skills on Conventional Biotechnology Material
Authors: Astika E. , Surtikanti H. K. , Kusnadi K. , Putra N. S.
Published: October 2022

The study aimed to find out students’ science process skill profile in grade XII. The research was conducted at SMAN 1 Tanah Putih Tanjung Melawan, Riau. The study was conducted by providing tests to students consisting of 10 questions on the scope of conventional biotechnology materials. This test used to measure students' science process skills, namely the ability to observe, communicate, interpret, propose hypotheses, apply concepts, ask questions, predict, use tools/materials, plan experiments, and classify. The research sample consisted of 70 students. The reliability value of the instrument was 0.948 of high category. It was obtained that the science process skill of students was categorized as medium with a percentage of 39.3%. The percentage of observing, communicating, interpreting, formulating hypotheses, applying concepts, asking questions, predicting, using tools/materials, planning experiments, and classifying abilities were 43.2%, 35.4%, 39.3%, 28.2%, 26.8%, 36.8%, 46.4%, 49.6%, 37.1%, and 50%, respectively. Some of the science process skill aspects showed a low category, namely in the aspects of formulating hypotheses and applying concepts. Other aspects showed medium category and almost all aspects were below 50%. The teacher’s role was very decisive as the main actor in improving students’ science process skills.
COVID-19 and arrhythmias - is there a relationship?
Authors: Akhmedov V. A. , Livzan M. A. , Gaus O. V.
Published: October 2022

COVID-19 infection is associated with many different systemic complications. Among these, cardiovascular system complications are particularly important as these are associated with significant mortality. There are many different subgroups of cardiovascular complications, with arrhythmias being one of them. Arrhythmias are especially important as there are a substantial percentage of patients who have arrhythmia after a COVID-19 infection, and these patients are seen with an increased mortality rate. Arrhythmias in COVID-19 patients are associated with inflammation, electrolyte abnormalities, hypoxia, myocardial ischemia, cytokines, pro-arrhythmic or QT-prolonging medications, and underlying heart conditions such as severe congestive heart failure, inherited arrhythmia syndromes, or congenital heart conditions. In addition, arrhythmias and cardiac arrests are most prevalent in the critically ill intensive care unit COVID-19 patient population. This review of PubMed/MedLine articled presents an overview of the association between COVID-19 and arrhythmias by detailing possible pathophysiological mechanisms, existing knowledge of pro-arrhythmic factors, and results from studies in adult COVID-19 populations.
Microtubules as a target of antitumor drugs
Authors: Dodokhova M. A. , Kotieva I. M. , Safronenko A. V. , Shlyk S. V. , Drobotya N. V. , Shpakovsky D. B.
Published: October 2022

The search for new antitumor and antimetastatic therapy targets is a priority task for interdisciplinary research in medical chemistry, experimental pharmacology and pathological physiology. One of the promising scopes of research in this direction is to study the possibility of modifying the polymerization process of tubulin, the main structural component of the microtubules in the cellular cytoskeleton. Various options for influencing microtubules can be used to repurpose already known and develop new antitumor drugs.
Сlinical portrait of the ambulatory patient with diabetes 2 types
Authors: Kudryashov E. A. , Skibitsky V. V. , Zabolotskikh T. B. , Kudryashova Y. A.
Published: October 2022

Objective: estimate the clinical status, a metabolic profile and carried-out cardiotropic, hypoglycemic therapy at outpatients with diabetes 2 types in real clinical practice.

Material and metods: the outpatient records of 81 patients of both sexes (average age 63.7 + 1.3 years, men 33 (40.7%) with type 2 diabetes mellitus, who are under dispensary observation in one of the polyclinics of Krasnodar, were analyzed. All patients had some clinical (“experience” of diabetes, body mass index) parameters, blood pressure level, laboratory indicators (fasting glycemia, glycated hemoglobin, total cholesterol, high and low density lipoproteins, triglycerides and medication (antihypertensive, lipid-corrective, antithrombotic, hypoglycemic) therapy evaluated.

Results: among patients with type 2 diabetes mellitus, women predominated, most of the patients had obesity of the 1st degree. In 27.2% there was no documented concomitant cardiac pathology, the rest had arterial hypertension and coronary artery disease. Antihypertensive therapy included from 2 to 5 drugs, including all patients receiving ACE inhibitors or sartans, which in 2/3 of cases were combined with amlodipine and in equal quantities with diuretics and beta-blockers. Only 8.5% of patients reached the target level of blood pressure. Lipid-lowering therapy in more than 90% of patients included statins in inadequately low doses, which led to the failure to achieve the target level of low-density lipoproteins in 95% of patients. Antithrombotic therapy was taken by more than 90% of patients, but in a quarter of them without documented indications. One in four outpatients with type 2 diabetes mellitus is diagnosed with nonvalvular atrial fibrillation. Only 71.4% of patients received direct oral anticoagulants. Among the means of hypoglycemic therapy, oral drugs (metformin, sulfonylurea derivatives) or their combination with insulin prevailed.

Conclusion: in most of the patients examined with type 2 diabetes, the main goals of cardiotropic and hypoglycemic therapy were not achieved. To improve the prognosis and quality of life of such patients, it is necessary to conduct comprehensive adequate treatment based on modern recommendations.
The gender features of the compound body composition in people of middle age with arterial hypertension
Authors: Gorban V. V. , Manto V. S. , Gorban E. V.
Published: October 2022

Objective: to study the parameters of the compound body composition in middle-aged people with arterial hypertension (AH) to determine the targets for prevention and treatment.

Materials and methods: 37 men and 58 women with AH aged 45 to 59 years were examined. Questioning, anthropometry with determination of waist circumference (WC), body mass index (BMI), study of compound body composition by bioimpedancemetry, as well as measurement of blood pressure (BP) were carried out.

Results: overweight and obesity were found in 87,3% of middle-aged people with AH. In both sexes, there was a direct correlation of visceral fat (VF) with age, BMI, WC and also with diastolic BP.

Conclusion: detection of hypertension, increased BMI, VF is necessary for diagnosing metabolic imbalance in middle-aged people in order to further conduct non-drug and preventive therapy, as well as reduce the development of possible complications.
Factors Associated With Intention and Use of e–Mental Health by Mental Health Counselors in General Practices: Web-Based Survey
Authors: De Veirman Ann E M , Thewissen Viviane , Spruijt Matthijs G , Bolman Catherine A W
Published: October 2022

Background

Mental health care counselors have a high intention to use e–mental health (EMH), whereas actual use is limited. Facilitating future use requires insight into underlying factors as well as eligibility criteria that mental health care counselors use in their decision to apply EMH.

Objective

The aim of this study was to unfold the intention and underlying reasons for mental health counselors to use EMH and to unveil the criteria they use to estimate patient eligibility for EMH. The theoretical framework was based on the reasoned action approach model, the Unified Theory of Acceptance and Use of Technology, and the Measurement Instrument for Determinants of Innovation model.

Methods

To empirically validate our theoretical model, a web-based survey was conducted among mental health care counselors (n=132). To unveil the eligibility criteria, participants were asked to rank their reasons for considering EMH suitable or unsuitable for a patient.

Results

The mean intention to use EMH was positive (mean 4.04, SD 0.64). The mean use of EMH before the COVID-19 pandemic was 38% (mean 0.38, SD 0.22), and it was 49% (mean 0.49, SD 0.25) during the pandemic. In total, 57% of the patient population was considered eligible for EMH. Usefulness and benefits (β=.440; P<.001), Task perception (β=.306; P=.001), and Accessibility (β=.140; P=.02) explained the intention to use EMH (F3,131=54.151; P<.001; R2=0.559). In turn, intention explained patient eligibility (F1,130=34.716; P<.001; R2=0.211), whereas intention and patient eligibility explained EMH use (F2,129=41.047; P<.001; R2=0.389). Patient eligibility partially mediated the relationship between intention to use EMH and EMH use, with a larger direct effect (c′=0.116; P<.001) than indirect effect (c=0.065, 95% CI 0.035-0.099; P<.001). Mental health counselors assessed patients’ eligibility for EMH mainly through the availability of computers and the internet and patient motivation.

Conclusions

To stimulate the use of EMH, intention and patient eligibility need to be influenced. Intention, in turn, can be enhanced by addressing the perceived usefulness and benefits of EMH, perceived accessibility, and task perception. Access to a computer and patients’ motivation to use EMH are important in facilitating patient eligibility. To cause an impact with EMH in general practice, mental health counselors need to be convinced of the benefits of EMH and transfer this enthusiasm to the patient. It is recommended to involve mental health counselors in the development of EMH to increase the (perceived) added value and use.
A Living Database of HIV Implementation Research (LIVE Project): Protocol for Rapid Living Reviews
Authors: Eshun-Wilson Ingrid , Ford Nathan , Le Tourneau Noelle , Baral Stefan , Schwartz Sheree , Kemp Christopher , Geng Elvin
Published: October 2022

Background

HIV implementation research evolves rapidly and is often complex and poorly characterized, which makes the synthesis of data on HIV implementation strategies inherently difficult. This is further compromised by prolonged data abstraction processes due to variable interventions, outcomes, and context, and delays in the publication of review findings; this can all result in outdated and irrelevant systematic reviews.

Objective

The LIVE project (A Living Database of HIV Implementation Research) aims to overcome these challenges by applying an implementation science lens to the conduct of rapid living systematic reviews and meta-analyses to inform HIV service delivery priorities and guideline development.

Methods

The LIVE project will generate a series of living systematic reviews exploring implementation strategies for improving HIV cascade outcomes (HIV infection, HIV diagnosis, linkage and retention in HIV care, viral suppression, and mortality). We will search Embase and MEDLINE as well databases specific to review questions for studies conducted after 2004 using predefined search terms to identify studies conducted in any age group or setting, and using implementation strategies that target policy makers, society, health organizations, health workers, and beneficiaries of care and their families. Both randomized controlled trials and observational studies will be included to ensure reviews include pragmatic data. In addition to assessments of methodological quality, features of the implementation strategies, relevance for implementation, and evidence quality will be determined using recognized frameworks. After initial publication, knowledge gaps will be identified, and review questions and search strategies revised to address ongoing critical areas of inquiry. Updated searches will be conducted every 6 months, with subsequent ongoing screening, data abstraction, and revision of meta-analyses.

Results

As of July 2022, five reviews are at various stages of development within the LIVE project. Three systematic reviews are underway and living review processes are in development for two reviews with estimated completion over the next 12 months.

Conclusions

This project and resulting systematic reviews will provide critical insights for HIV service delivery to inform international guideline development.

International Registered Report Identifier (IRRID)

DERR1-10.2196/37070
The Limitations of User-and Human-Centered Design in an eHealth Context and How to Move Beyond Them
Authors: van Velsen Lex , Ludden Geke , Grünloh Christiane
Published: October 2022

Human-centered design (HCD) is widely regarded as the best design approach for creating eHealth innovations that align with end users’ needs, wishes, and context and has the potential to impact health care. However, critical reflections on applying HCD within the context of eHealth are lacking. Applying a critical eye to the use of HCD approaches within eHealth, we present and discuss 9 limitations that the current practices of HCD in eHealth innovation often carry. The limitations identified range from limited reach and bias to narrow contextual and temporal focus. Design teams should carefully consider if, how, and when they should involve end users and other stakeholders in the design process and how they can combine their insights with existing knowledge and design skills. Finally, we discuss how a more critical perspective on using HCD in eHealth innovation can move the field forward and offer 3 directions of inspiration to improve our design practices: value-sensitive design, citizen science, and more-than-human design. Although value-sensitive design approaches offer a solution to some of the biased or limited views of traditional HCD approaches, combining a citizen science approach with design inspiration and imagining new futures could widen our view on eHealth innovation. Finally, a more-than-human design approach will allow eHealth solutions to care for both people and the environment. These directions can be seen as starting points that invite and support the field of eHealth innovation to do better and to try and develop more inclusive, fair, and valuable eHealth innovations that will have an impact on health and care.
Mobile Apps for the Management of Gastrointestinal Diseases: Systematic Search and Evaluation Within App Stores
Authors: Messner Eva-Maria , Sturm Niklas , Terhorst Yannik , Sander Lasse B , Schultchen Dana , Portenhauser Alexandra , Schmidbaur Simone , Stach Michael , Klaus Jochen , Baumeister Harald , Walter Benjamin M
Published: October 2022

Background

Gastrointestinal diseases are associated with substantial cost in health care. In times of the COVID-19 pandemic and further digitalization of gastrointestinal tract health care, mobile health apps could complement routine health care. Many gastrointestinal health care apps are already available in the app stores, but the quality, data protection, and reliability often remain unclear.

Objective

This systematic review aimed to evaluate the quality characteristics as well as the privacy and security measures of mobile health apps for the management of gastrointestinal diseases.

Methods

A web crawler systematically searched for mobile health apps with a focus on gastrointestinal diseases. The identified mobile health apps were evaluated using the Mobile Application Rating Scale (MARS). Furthermore, app characteristics, data protection, and security measures were collected. Classic user star rating was correlated with overall mobile health app quality.

Results

The overall quality of the mobile health apps (N=109) was moderate (mean 2.90, SD 0.52; on a scale ranging from 1 to 5). The quality of the subscales ranged from low (mean 1.89, SD 0.66) to good (mean 4.08, SD 0.57). The security of data transfer was ensured only by 11 (10.1%) mobile health apps. None of the mobile health apps had an evidence base. The user star rating did not correlate with the MARS overall score or with the individual subdimensions of the MARS (all P>.05).

Conclusions

Mobile health apps might have a positive impact on diagnosis, therapy, and patient guidance in gastroenterology in the future. We conclude that, to date, data security and proof of efficacy are not yet given in currently available mobile health apps.
Динаміка біохімічних маркерів рабдоміолізу при політравмі
Authors: Krishtafor D.A. , Klygunenko O.M. , Kravets O.V. , Yekhalov V.V. , Stanin D.M.
Published: October 2022

Актуальність. Травматичні ушкодження нерідко призводять до рабдоміолізу — руйнування м’язової тканини, що призводить до витоку внутрішньоклітинного вмісту міоцитів у кровоток. Окрім краш-синдрому, причинами травматичного рабдоміолізу можуть бути пряме пошкодження м’язів при масивних травмах кісток та м’яких тканин, м’язова гіпоксія на тлі краш-синдрому, синдрому системної запальної відповіді або гіповолемічного шоку, а також синдром позиційного стискання при тривалих операціях, агресивна та тривала ретракція м’яких тканин під час операцій, множинні та складні оперативні втручання та тривале використання турнікетів. Найбільш значущими біохімічними маркерами рабдоміолізу є креатинкіназа та міоглобін. Метою нашого дослідження було провести аналіз динаміки біохімічних маркерів рабдоміолізу у постраждалих із мирною та бойовою політравмою. Матеріали та методи. Обстежений 121 постраждалий із політравмою. Досліджувалися потреба в стимуляції діурезу та замісній нирковій терапії, рівні сечовини та креатиніну крові, рівні загальної креатинкінази (КК), КК-МВ та міоглобіну сироватки крові. Результати. Рівень загальної КК понад 5000 Од/л при надходженні корелював із летальністю. У постраждалих, які вижили, рівень загальної КК починав знижуватися через 24 години після травми та на 14-ту добу перевищував норму усього у 2 рази. У постраждалих, які померли, рівні КК залишалися на вихідному рівні або підвищувалися. Рівні КК-МВ не показали вірогідного зв’язку з летальністю, але у постраждалих із тяжкими бойовими травмами кінцівок, перенесеною масивною трансфузією та потребою в замісній нирковій терапії спостерігалося тривале та стійке підвищення цього показника. Вихідний рівень міоглобіну не мав кореляції з летальністю в подальшому, але в пацієнтів, які вижили, рівні сироваткового міоглобіну швидко знижувалися, тоді як у померлих залишалися на сталому рівні або підвищувалися повторно після деякого зниження. Рівні маркерів рабдоміолізу мали чіткий зв’язок із показниками функції нирок та потребою в стимуляції діурезу та/або замісній нирковій терапії, причому у КК та КК-МВ цей зв’язок формувався вже через 6 годин після надходження постраждалого до стаціонару, а в міоглобіну — із 3-ї доби. Склад поповнення травматичної крововтрати також впливав на показники маркерів рабдоміолізу. Об’єм введених у першу добу штучних колоїдів, СЗП та еритроцитів був прямо пов’язаний із рівнями КК, КК-МВ та міоглобіну на усіх етапах дослідження. Висновки. Таким чином, політравма з масивною крововтратою супроводжується рабдоміолізом, вираженість якого залежить від тяжкості травми, та є предиктором гострого пошкодження нирок та летальності. Відсутність зниження рівнів КК та міоглобіну на тлі інтенсивної терапії є несприятливим прогностичним критерієм. У постраждалих із тяжкою політравмою рівні КК, КК-МВ та міоглобіну доцільно досліджувати в динаміці.
Ураження внутрішніх органів при інтоксикації ціанистими сполуками
Authors: Tkachishin V.S.
Published: October 2022

Синильна кислота є слабкою кислотою, водні розчини якої мають невиражений запах гіркого мигдалю. Похідні синильної кислоти мають назву ціанідів (ціанистий калій, ціанистий натрій). В умовах виробництва отруєння синильною кислотою і її сполуками можливе внаслідок вдихання її парів. Рідше вони потрапляють в організм через шкіру й шлунково-кишковий тракт. Токсичність синильної кислоти пояснюється спорідненістю її молекули з тривалентним залізом тканинного дихального ферменту цитохромоксидази. Ціанисті сполуки блокують його, позбавляючи можливості реагувати з киснем, у результаті чого виникає кисневе голодування тканин — тканинна гіпоксія. Найбільш страждає від гіпоксії центральна нервова система, зокрема зони, розміщені близько до дихального центру. Розрізняють гостре й хронічне отруєння ціанистими сполуками. Потерпілого необхідно вивести на чисте повітря. Необхідно швидко зняти забруднений одяг і розпочати надання медикаментозної допомоги. Медикаментозне лікування хворих з гострою інтоксикацією, викликаною ціанистими сполуками, базується на трьох основних принципах: 1) утворення так званого бар’єра в крові за допомогою внутрішньовенного введення метиленового синього, а також шляхом вдихання амілнітриту; 2) нейтралізація отрути шляхом введення великої кількості глюкози, яка сприяє утворенню нешкідливих сполук — ціангідриду й тіосульфату натрію; 3) вплив на окисні процеси в тканинах, для чого негайно починають проводити вдихання карбогену. У профілактиці отруєнь велике значення мають герметизація апаратури й устаткування, застосування місцевої витяжної вентиляції, механізація виробничих процесів, ретельний періодичний контроль за станом повітря в робочих приміщеннях. За необхідності роботи в контакті з парами синильної кислоти і її сполук обов’язковим є носіння протигаза.
Circular Economy Policy of Shrimp Waste as an Effort to Implement Green Economy
Authors: Suning Suning , Walujo Djoko Adi , Rohmadiani Linda Dwi , Prihono Prihono
Published: October 2022

This study aims at determining the conditions and characteristics of shrimp waste, the economic value of the potential for shrimp waste, as well as the policy direction for implementing the Circular Economy of Shrimp Waste as a Green Economy Alternative in the Bulak Banteng Kenjeran Coastal Area, Surabaya City. The research method used is descriptive qualitative and quantitative with the process hierarchy analysis technique (AHP). The data collection method was carried out by distributing questionnaires and in-depth interviews with selected respondents. The results showed that the characteristics of shrimp waste in the form of shrimp heads and shells were still not used for economic value activities, and people dumped them in gutters around homes and at sea. The priority policy directions that can be applied to the Circular Economy of Shrimp Waste as an Alternative to a Green Economy are; 1) providing innovation and technology for economic-based shrimp waste processing with a total CR (consistency ratio) value of 1.878; 2) to improve environmental health by not disposing of shrimp waste around the house, the total value of CR is 1.127; and, 3) the government provides a shrimp processing industry for fishermen with a total CR value of 0.094. Each policy priority can be carried out in synergy so that shrimp waste can be handled properly.
Experimental Study on Solar Air Heating
Authors: Chaichan Miqdam T , Ali Ali J. , Abass Khaleel I.
Published: October 2022

تم تصميم وتصنيع وفحص عمل نوع جديد من مسخنات الهواء الشمسية في اجواء مدينة بغداد- العراق. يتكون مسخن الهواء من جزئين رئيسين. الجزء الافقي ملأ برايش الحديد سوداء اللون بينما ثبتت خمسة انابيب مملوءة بمادة الشمع البرافينيي متغيرة الطور في الجزء العمودي. ثبتت مروحة عند فتحة خروج الهواء. تمت دراسة حالتين: عندما يتحرك الهواء بفعل الحمل الطبيعي والحالة الثانية عندما يتحرك بفعل الحمل القسري.اثبت مسخن الهواء المدروس كفاءته اذ انه سخن الهواء المار خلاله الى درجات حرارة عالية. بينت النتائج ان تحريك الهواء بسرع منخفضة يجعل درجات الحرارة والطاقات المخزونة و الكفاءات للحالتين المدروستين تتقارب. ان شدة الاشعاع الشمسي لمدينة بغداد مناسبه جدا لاستخدام مسخنات الهواء الشمسية والتي من شأنها ان تقلل استهلاك الكهرباء والوقود الاحفوري.
Physical and Morphological Properties of Hard- Soft Ferrite Functionally Graded Materials
Authors: Chyad Fadhi , Jabur Akram , Abed Sabreen
Published: October 2022

Functionally graded materials (FGMs), with ceramic –ceramic constituents are fabricated using powder technology techniques. In this work three different sets of FGMs samples were designed in to 3 layers, 5 layers and 7 layers. The ceramic constituents were represented by hard ferrite (Barium ferrite) and soft ferrite (lithium ferrite). All samples sintered at constant temperature at 1100oC for 2 hrs. and characterized by FESEM. Some physical properties were measured for fabricated FGMs include apparent density, bulk density, porosity, shrinkage and hardness. The results indicated that the density increase with the increase the number of layer. Lateral shrinkage is one of the important parameter for estimating the quality of component gradation in an FGM structure. The Vickers hardness show higher value at FGM7, Finally the FESEM images showed a gradation in microstructure within the system from plate- like structure for the hard ferrite to spherical structure for the soft ferrite.
Editorial: Participatory Evaluation and Impact Assessment in Citizen Science
Authors:   ZSI - Centre for Social Innovation, Mayer Katja , Schürz Stefanie , Kieslinger Barbara , Schaefer Teresa
Published: October 2022

Editorial to the fteval Journal's special issue #54
Evaluating citizen science initiatives through a citizen science-based approach
Authors:   Knowledge and Innovation, D'Andrea Luciano , Kalpazidou Schmidt Evanthia , Bužan Elena , Vidal Merino Mariana , Dall Elke , Colonnello Claudia , Graversen Ebbe Krogh , Cerri Jacopo , Iacolina Laura , Feudo Fabio
Published: October 2022

Citizen Science (CS) has gained increased recognition over the last two decades. This turn is occurring in strong connection with the profound transformations that have affected science over the last few decades, leading towards a new social model of science characterised by greater openness to society regarding research content actors involved, research processes, and expected societal and economic impact. CS is at the centre of this complex change dynamics as a tool that strongly sustains the shift towards the “open social model” of science supporting a new approach to the science-society relationship. However CS is rarely evaluated for its long-term structural effects on science and the science-society relationship. This article addresses this topic, having as a point of departure the ongoing EC-funded Step Change project, aimed at promoting five Citizen Science Initiatives (CSIs) in different research fields (health, energy, and environment). Under the project, an Evaluation Framework has been developed, shaping the evaluation process as a citizen science project by adopting a developmental and participatory approach. The Evaluation Framework is organised into two different but intertwined levels, one focused on the evaluation of the individual CSI (analytical level) and a second aimed at identifying recurrent patterns of obstacles, facilitating factors, or a mix of them (neutral situations) across the CSIs (cross-cutting level). While the analytical level is intended as a service to better implement the CSIs, the cross-cutting level is intended as a research process to generate new knowledge on how CS could serve as a tool for a better anchorage of science into society.
The “payback“ of citizen science: A participatory evaluation and impact assessment model for social innovation projects
Authors:   Münster University of Applied Sciences, Münster School of Business, Uude Katrin , Kurzhals Kerstin , Wesbuer Annika
Published: October 2022

Citizen science projects for social innovation present solutions to society’s complex challenges (da Silva et al. 2019). However, evaluating their impact is challenging (Bornmann 2012); an integrative impact-assessment framework considering all innovation process steps and impact dimensions while accounting for all participants’ perspectives does not yet exist (Smit and Hessels 2021). One frequently used framework to evaluate impact beyond the academic sector is the Payback Framework proposed by Buxton and Hanney (1996). In its current specification, this framework does not apply to participatory projects due to its unilateral scientific perspective. This study applied the theory adaptation approach (Jaakkola 2020) to extend the Payback Framework’s scope by informing it with the lens of another conceptual approach, namely the Service-Dominant logic. The study aimed to adapt the Payback Framework for citizen science projects, creating a Citizen Science Payback Framework. The new framework was created by adding the degree of external participation as a third component. The new component captures citizen participation and thus indicates the involvement of citizens in the evaluation process.
¿El fin del outsourcing en México? Características de la nueva legislación y perspectivas de futuro
Authors: Brito Laredo Janette , Carrillo Viveros Jorge , Gomis Hernández Redi , Hualde Alfaro Alfredo
Published: October 2022

Objetivo: analizar la subcontratación laboral en la reforma a la Ley Federal del Trabajo de México, aprobada en abril de 2021, compararla con la de 2012 y reflexionar sobre sus probables efectos en la dinámica laboral. Metodología: se compararon las dos últimas reformas para determinar qué se modificó y qué permanece en relación con la subcontratación laboral. Se revisaron los debates políticos y la dinámica cuantitativa en años recientes. Resultados: en algunos puntos los cambios son significativos; en otros, permanecen las normas anteriores. El giro más importante de la reforma atañe a los mecanismos de garantía para el cumplimiento de la norma. Limitaciones: el poco tiempo transcurrido desde la promulgación de la nueva reforma constituye la principal limitación para el análisis de sus consecuencias. Valor: el análisis y las conclusiones son un aporte novedoso a la discusión académica sobre los efectos de los giros políticos en los fenómenos sociales. Conclusiones: la reforma sobre la subcontratación presenta al mismo tiempo rupturas con la normatividad anterior y continuidad. Las consecuencias preliminares son inciertas. Hay indicios para pensar que la subcontratación laboral disminuirá de forma sustantiva, pero no la precarización.
President Joko Widodo's Leadership Style Model in Controlling Covid-19
Authors: Fahlevy Muhammad Reza , Noor Muhammad , Gunawan I Ketut , Mahfin Amera
Published: October 2022

During the current COVID-19 pandemic, many state leaders must make decisions quickly. Quick decision-making also has a positive impact on society and the country. Leadership style greatly influences a president in managing a pandemic. As head of state, the President can use his executive power to solve problems, especially pressing ones. This study aims to examine the model of the President's leadership style in dealing with the COVID-19 pandemic in Indonesia. In addition, this model will be the basis for forming a particular program that focuses on developing leadership competencies and being an evaluation in urgent situations. This type of research is qualitative. The data used in this study is a literature study that focuses on using secondary data in the form of forty news media articles taken from March 2, 2020, to October 2020. The analysis of news media data was managed using Nvivo 12 Plus software through coding and cross-tabulation analysis. The results of this study are the model of President Joko Widodo's leadership style, applying various leadership styles in controlling the COVID-19 pandemic in Indonesia. This study concludes that the leadership style is inefficient in handling the COVID-19 pandemic, even though President Joko Widodo has directly taken over the handling of the crisis.
The Special Autonomy Funds are not for Poverty Alleviation: A lesson from Aceh's Way
Authors: Ikhsan  , Hajad Vellayati , Marefanda Nodi , Saputra Akmal , Herizal
Published: October 2022

This article is about the Allocation of the Special Autonomy Fund's efforts to combat poverty in Aceh. The Special Autonomy Fund began in 2008 and will continue until 2027, with the goal of achieving the highest level of peace in Aceh. Data is derived from interviews and supporting documents from the Bappeda Aceh and the Indonesian Ministry of Finance, as well as a quantitative method based on case studies. Following that, data is analyzed through the methods of display, reduction, and data analysis. The findings indicate that the Aceh Special Autonomy Fund is unable to significantly reduce poverty levels in Aceh. The key point is that the Special Autonomy Fund is not pro-poor budgeting and is failing to address the poverty problem in Aceh.