bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of Using the Multimedia Modality Principle to Teach Shakespearean Drama
Authors: Aljabr Fahad , Bani-Salameh Zakariya A.
Published: August 2023

The present study investigates the effect of the modality principle in multimedia learning during the teaching of drama at the English department at a Saudi university, the University of Ha’il. It compares explicitly the impact of using static pictures and narration concurrently with on-screen text for the control group with the impact of using pictures with narration only for the experimental group. A sample of 69 male English-majoring students was selected and divided into control and experimental groups. The aim was to determine which group performed better than the other with the hypothesis that audio-visual presentation of the selected content would enhance students’ knowledge retention and mental skills and would lead to better learning outcomes for the experimental group. A quasi-experimental design was adopted and ANCOVA test was used to observe variation in the scores of the two groups after studying Hamlet’s play. The results support the hypothesis. Students in the experimental group outperformed their counterparts in the control group. This was observed in the post-tests on the retention of knowledge and mental skills. The findings of this study provide additional evidence of the superiority of audio-visual presentation in a previously unstudied context related to the teaching of literary content.
Pictorial-Based Learning Model for Remote Vocabulary Learning: A Systematic Review
Authors: Hamsan Nurul Hanna , Tahir Mohd Haniff Mohd , Ing Benjamin Loh Hsien
Published: August 2023

This systematic review was conducted to provide inspiration on the development of a learning model for vocabulary learning via the use of pictorials, as well as the omissions and gaps in the synthesized literature on the topic, especially with regards to the use of such a model for remote learning. The significance of this particular study lies in the affirmation of whether this pictorial-based vocabulary learning model is a viable solution for the necessity of remote learning. There are a total of three research questions, which are (1) What are the benefits of developing a pictorial-based vocabulary model for learning vocabulary? (2) What are the challenges in the integration and application of digital technology for remote learning and learning enhancement? and (3) How effective is using pictorial elements in enhancing students’ learning of vocabulary? Two main databases – ResearchGate and Scopus – were explored for data collection. A total of 16 studies of relevance to the topic of investigation were retained for further analysis out of more than 50 studies after the strict process of removing duplicates and scrutinizing the abstracts for a suitable level of relevance. To account for the derivation of the various themes under this review, the method of a thematic analysis was preferred. The emerging themes being analyzed are: (1) The Development of a Pictorial-Based Learning Model for Vocabulary Learning (2) The Integration and Application of Digital Technology for Remote Learning and Learning Enhancement (3) The Effectiveness of Using Pictorial Elements on Enhancing Students’ Learning of Vocabulary.
The Analysis of Feasibility in EFL Textbook: A Contribution to Kurikulum Merdeka
Authors: Senowarsito  , Suwandi  , Musarokah Siti , Ardini Sukma Nur
Published: August 2023

The researchers would like to combine theories from Tomlinson and Buku Saku Tanya Jawab Kurikulum Merdeka that never been done previously by analyzing the feasibility features of a textbook entitled English for Junior High School Students: Pragmatics Based designed by the researchers themselves as an R & D product of the research. The study can make a valuable contribution to the field of education by providing insights into the development of a new textbook that focuses on pragmatics. It employed a descriptive qualitative research design with the designed textbook for seventh-grade students as the research object, then analyzed using two theories mentioned previously. Based on the findings, the textbook fulfills sixteen criteria proposed by Tomlinson. It can be utilized as a supplement to the study findings and as a learning tool in the classroom as well as this research contributes to Kurikulum Merdeka while also meeting the needs of teachers and students. The combination of viewing and presenting activities can enhance students’ comprehension of English as well as their speaking, listening, and idea-organizing abilities in the language. Both viewing and presenting must be seen in the English learning curriculum as crucial skills that complement one another and must be taught in an integrated way. The textbook is also equipped with audio and videos accessed via Android and iOS. Based on those findings, the textbook contributes to the latest curriculum that is Kurikulum Merdeka as a valuable supplementary textbook. Therefore, there are opportunities to conduct additional research on this topic.
Citizen Scholar Chapter 6: Social Media
Authors: Cohen Philip N.
Published: August 2023

This is a draft of chapter 6: Social Media, in the book, Citizen Scholar, under contract with Columbia University Press. I’m circulating it now for comment and criticism.
The Coming Malthusian Catastrophe: The Climate and Biodiversity Crises as Global Food Crisis.
Authors: Blaber Richard Michael
Published: August 2023

Thomas Malthus predicted that human population would always grow faster than food production, but the ‘Green Revolution’ of the 1960s appeared to disprove his thesis. Now anthropogenic climate change, with its adverse impacts on crop yields, the supply of water for irrigation, and the health and increased mortality of farm animals, is once again threatening to vindicate him, as human population grows from 8 billion now to an estimated 9.74 billion by 2050. Human-induced biodiversity loss is compounding this problem.
Capacidade de Trabalho
Authors:   508592151, Santos Mónica , Almeida Armando , Lopes Catarina
Published: August 2023

Introduction/framework/objectives The concept itself is not exotic to Occupational Health and Safety professionals, nor does include very complex considerations that are not partially assimilated; however, not all of them will have delved into the subject, so the need arose to prepare a review that would address this. Methodology This is a Bibliographic Review, initiated through a survey carried out in January 2022, in the RCAAP database. Contents The concept of Ability to Work becomes increasingly relevant with the aging of the general population and the active population, due to the fact that retirement tends to be later, in most countries. The concept is broad, complex and multidimensional. Work Capacity is a product of resources versus the physical, mental and social demands of work. It reflects how well an employee is doing now and in the near future; it is the perception that they have of their current productive capacity, comparing it with the best that ever existed. Greater Work Capacity is associated with well-being, greater productivity and more quality of performance. To quantify, there is the Work Capacity Index, translated and validated for Portugal. Discussion and Conclusions Once in possession of concrete data that modulate Work Capacity, the professionals of the Occupational Health and Safety Teams are more likely to enhance their actions, in order to obtain healthier and safer work environments, making employees more satisfied and productive, generating better performance and higher profits for the employer. It would be interesting for some teams with ongoing projects on the subject to disclose the steps they have taken, so that the evidence produced helps professionals in this area. KEYWORDS: work capacity, work capacity index, safety at work, occupational health and occupational medicine.
Vigilância da Tuberculose nos Profissionais de Saúde como contributo na erradicação de uma Pandemia
Authors: Matos Sara , Duarte Ana , Almeida Maria , Gonçalves Inês , Miranda Mário , Abreu Miguel
Published: August 2023

Introduction/Framework Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Despite the available treatment, it’s an important driver of global morbidity and mortality. It reaches mainly the lungs but can reach any organ. The main route of infection is inhalation of aerosolized particles or contaminated micro-droplets. Global efforts for early diagnosis and adequate treatment have made it possible to remove Tuberculosis from the worldwide ten leading causes of death in 2019. The worldwide incidence is around ten million, probably underestimated. Tuberculosis represents an often-overlooked pandemic, which remains an important cause of death from an infectious disease whose, in contrast to other infections, incidence has recently risen as occupational disease. Methodology It’s a narrative review of the national and international guidelines about Tuberculosis in healthcare workers, with an adaptation to the Portuguese reality using estimations from countries with a similar disease incidence. Contents The World Health Organization argues that the benefit of screening and treating Latent Tuberculosis Infection outweighs the individual risks and therefore should be performed whenever possible. Following these guidelines, the Portuguese health council (Direção-Geral da Saúde) determined that health institutions, within the scope of health surveillance of their workers, must adopt procedures that allow for the early detection of Tuberculosis and Latent Tuberculosis Infection. Thus, the Occupational Medicine Services are responsible for assessing and manage the professional exposure to this biological agent. The End TB Strategy program aspires to the worldwide eradication of Tuberculosis by 2035, aiming to reduce Tuberculosis incidence and mortality by 80 and 95%, respectively, as well as universal access to proper treatment. Discussion and Conclusions The authors argue that the institutional contribution with the reinforcement of hospital infection control measures, the implementation of regular occupational Tuberculosis surveillance programs and the containment of the disease, through timely screening after unprotected exposure, are essentials measures for the achievement of the ambitious outlined goals. Regardless of their job model, these programs should be applied to all workers, contributing to the maintenance of their health, the main Occupational Medicine’s goal. Finally, the authors share ten common questions from daily basis clinical practice and present methodological suggestions. KEY-WORDS: Labor Health Surveillance; Healthcare workers; Prevention of Occupational Diseases; Screening; Tuberculosis; Latent Tuberculosis Infection.
Impacto Laboral da Perturbação Obsessivo-Compulsiva: Caso Clínico
Authors: Talambas Sofia , Amaral Maria , Vieira Ana , Rodrigues Miguel , Manzano Maria
Published: August 2023

Introduction Obsessive-Compulsive Disorder (OCD) is a common psychiatric pathology, classically considered chronic and debilitating because of the significant impact it can have on overall patient functionality, including at work. Its etiology is still unclear, and the clinical presentation is quite heterogeneous, manifesting itself through obsessions and/or compulsions that are associated with high levels of anxiety and time consumption. Case Report A 40-year-old female, working as an administrative assistant in a hospital, with a history of almost 20 years of obsessive doubt and verification rituals. Due to the worsening of symptoms, and their high impact on work capacity, she started a psychiatry follow-up. Then, according to the employee’s expectations and limitations, she was transferred to a different workstation, with less social interactions and different responsibilities. Subsequently, after both interventions, significant clinical improvement was shown. Discussion The close relationship between Occupational Medicine and Psychiatry, unequivocally contributes to manage mental illness in the workplace, either identifying reasonable adjustments to meet the needs of workers with mental illness, or attending the ones noticed during their regular activities. Conclusion It is essential to implement strategies for effective communication between both medical specialities, and aim to prevent occupational risks, by protecting and promoting healthy workplaces. Keywords: Obsessive Compulsive Disorder; Psychiatry, Occupational Health.
Autonomia no Trabalho
Authors:   508592151, Santos Mónica , Almeida Armando , Lopes Catarina
Published: August 2023

Introduction/framework/objectives Labor Autonomy can be related to well-being, increased performance and productivity of employees, translating into obvious gains for employers as well. Given these premises, areview was developed to better contextualize. Methodology This is a Bibliographic Review, initiated through a search carried out in January 2022, in the databases “CINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina and RCAAP”. Contents Individual autonomy can be defined as self-determination, possibility to execute objectives, with freedom to choose/plan and act according to values ​​and goals; that is, the possibility of choosing without interference and with respect from others in relation to the decisions taken. Thus, the individual easily considers that the entire process was valid and meaningful. However, such freedom (which is never absolute) implies responsibility. Autonomy at work is a more restricted concept than individual autonomy since there will always be some subordination to the market/institution. Even so, worker will be able to have the freedom to determine some items, but also being held responsible for doing so. There is Autonomy to the freedom in the exercise of functions and tasks (in a more restricted sense), as also the ability to decide and intervene in the work process, influencing the global organization, working conditions, including possible self-monitoring/self-assessment, in a broader sense. In the same institution, there may be different levels of individual and group autonomy. Real Autonomy implies a voluntary internal division of tasks; in turn, subordinated or contained autonomy is controlled, has limits and can even be associated with situations of exploitation. Discussion and Conclusions Most documents associate Autonomy with something positive in occupational terms; however, in reality, and also depending on the specific subtype and context, it can imply anxiety, more responsibility and worse working conditions. It may be up to the Occupational Health and Safety team to train employers, managers and workers, to make each institution evolve in the sense that all these parts benefit more. It would be relevant for some teams already with projects in this area to be able to disseminate their results and conclusions, according to the publication of scientific papers. Keywords: autonomy, occupational health and occupational medicine.
Carcinoma da Tiroide: Diagnóstico em exame de Saúde de Medicina do Trabalho e Aptidão ao Trabalho por Turnos
Authors: Saldanha Nuno , Pereira Raquel , Matos Pedro , Teófilo Vanessa , Ribeiro Carla , Pinho Paulo , Norton Pedro
Published: August 2023

Introduction Thyroid carcinomas include a wide spectrum of lesions. The well-differentiated subtype, 90% of all thyroid cancers, is associated with an excellent prognosis. Several risk factors are described. The most important environmental factor is exposure to ionizing radiation, although shift work is proposed as a prominent factor. The common clinical presentation of thyroid carcinoma is a thyroid nodule detected by the patient or imaging tests. Case Report This is a 25-year-old nurse who came to the occupational health service with complaints of enlarged cervical nodes. She denied prominent personal background. She had a palpable mass in the thyroid and right supraclavicular region and dysphonia with six to nine months of evolution. She underwent cervical ultrasound with biopsy that revealed papillary thyroid carcinoma with lymph node metastasis. She had surgery and radioactive iodine treatment. In occupational health, she was conditioned to shift work. Discussion Surgical removal and radioactive iodine treatment cures more than 90% of localized and well-differentiated thyroid carcinomas. Well-differentiated thyroid carcinoma with metastases is associated with a 90% ten-year survival if there is good iodine supply and the tumor goes into remission after treatment. A relationship between circadian cycle dysfunction and thyroid carcinoma is proposed, so it is important to decide the ability to work at night in the follow-up period of the disease. Conclusion The relevance of the case arises with the aim of alerting to the advantages of an Occupational Health service and its ability to provide a timely and rapid response to various pathologies of the working population with important health gains. This case also offers a rationale for the management and time of shift work avoidance in the post-diagnosis of thyroid carcinoma. Keywords: thyroid carcinoma; shift work; occupational medicine; occupational health.
Bissinose
Authors:   508592151, Santos Mónica , Almeida Armando , Lopes Catarina
Published: August 2023

Introduction / framework / objectives The interest in applying task rotation to mitigate some occupational risk factors has been mentioned for a long time but, in reality, most professionals working in Occupational Health teams do not have experience in the development of these schemes and, perhaps, may even not knowing that there are computer algorithms that could aim the whole process more scientifically. Methodology This is a Bibliographic Review, initiated through a search carried out in August 2021 in the databases “CINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina and RCAAP”. Contents Rotation is an administrative technique used with the objective of preventing Musculoskeletal Injuries; however, designing a rotation protocol can be complex in some circumstances. It can be defined as the change of tasks in a cyclic and regular way, in a previously stipulated order, in a certain interval. Advantages cover the Employee and/or Employer. Rotation can be decided by the hierarchical superior or by the employees themselves (with autonomy); in the latter case the acceptability is higher. Discussion and Conclusions Job rotation seems to be a good option in general work situations, as long as it is well considered; for more complex situations, computer programs/algorithms may be used to assist in the process. KEYWORDS: rotation, occupational health, occupational safety and occupational medicine.
Comprehensive Musicianship, A Practical Resource
Authors: Harlow Randall , Peyton Heather , Schwabe Jonathan , Swilley Daniel
Published: August 2023

This OER presents an integrated suite of learning resources developed for the core music theory and musicianship curriculum at the University of Northern Iowa School of Music. It provides a more comprehensive symbiosis of musicianship and music theory learning than can be found in existing textbooks, including engaging and progressive video demonstrations and interactive listening and vocal exercises that integrate musical knowledge with foundational musical skills. This OER affords the flexibility to shape core musicianship and music theory learning to meet the needs of changing School of Music demographics well into the future, a resource for innovative and inviting music programs accessible to all.
ТРАНСФОРМАЦІЙНІ ПРОЦЕСИ СИСТЕМИ СУДОЧИНСТВА В УКРАЇНСЬКИХ ЗЕМЛЯХ ПІСЛЯ СУДОВОЇ РЕФОРМИ 1864 РОКУ
Authors: Скоморовський В.Б. , Сендецький В.Р.
Published: August 2023

У статті розкриваються  трансформаційні процеси системи судочинства на українських землях після Судової реформи 1864 року. Зазначається, що судова реформа була важливим елементом реформування загальноімперського законодавства середини ХІХ століття. Вона характеризувалася найбільшою послідовністю серед заявлених тогочасних перетворень загальноімперського законодавства. Її переваги доволі чітко проявилися на фоні судових порядків, що існували у дореформений період. Стверджується, що необхідність реформування судової системи стала об’єктивною потребою часу, адже на території країни існувало надзвичайно широке коло судових інстанцій, підсудність яких часто не була визначена, спостерігався різний порядок судочинства, що у підсумку негативно позначилося на процедурі звернення до суду задля захисту своїх прав та інтересів. Наголошується, що проголошені після судової реформи  демократичні принципи дали можливість запровадити новий суд, який мав всестановий характер, і був покликаний забезпечити належні гарантії справедливого і неупередженого судового розгляду. Такий принцип мали втілювати судові палати, які запроваджувалися по усі території країни.  Зауважується, що на території українських губерній у різний проміжок часу було створено Харківську, Одеську та Київську судові палати. У процесі заснування нових судових інституцій судові палати мали повноваження здійснювати різноманітні види діяльності. Значення судових палат неухильно зростало і поступово вони ставали суттєвим та ефективним елементом запровадження судових перетворень в країні. Палати проголошувалися апеляційною інстанцією стосовно рішень окружних судів, а також діяли як суд першої інстанції із визначених законом справ. Відзначено, що поряд із судовими палатами діяли мирові суди, які розглядали дрібні цивільні та кримінальні справи та окружні суди, до компетенції яких належали справи, що не відносились до сфери відання мирових суддів та компетенції судових палат. Найвищим судовим органом визначався Сенат. Зазначається, що трансформаційні процеси системи судочинства проходили не завжди злагоджено та зустрічали неабиякі труднощі. Це пов'язувалось насамперед з тим, що окремі території за своїм розвитком та складом були різними, а тому одночасне втілення норм судових статутів у межах цілої країни не видавались можливим. Поставало питання щодо фінансового та кадрового забезпечення реформи, яке на старті судових трансформацій вирішено не було. З огляду на це втілення норм судових статутів суттєво гальмувалося, що часто призводило до неузгодженості у діяльності членів судових установ, а також позначалося на ефективності функціонування судових інституцій.
ТЕОРЕТИЧНІ АСПЕКТИ ВИЗНАЧЕННЯ ЗМІСТУ ЮРИДИЧНОЇ ВІДПОВІДАЛЬНОСТІ В СИСТЕМІ ПРАВА
Authors: Дубовой А.С. , Загребельна Н.А.
Published: August 2023

У статті проведено всебічний теоретичний аналіз однієї з фундаментальних правових категорій «юридична відповідальність» як соціально-правової доктрини та правил поведінки в соціумі. Виділено та систематизовано сучасні наукові погляди та думки щодо цієї категорії з усіма її варіаціями. Виділено три основні підходи до визначення юридичної відповідальності: негативістський (відповідальність за факт вчинення протиправного діяння), позитивістський (всеохоплюючий в часі), цілісно-правовий (як загальний напрямок розвитку права). Доведено прямий зв’язок понять відповідальності з необережністю, умислом чи недбалістю правопорушника. Доведено, що інститут відповідальності є фундаментальним механізмом в правовій системі України.В статті з’ясовано, що будь-яка концепція в праві, так само як і концепція дуалізму при розгляді підходів до визначення юридичної відповідальності, має свої недоліки. Якщо розглядати її лише з одного боку (наприклад, з боку негативізму), то не будуть враховані основоположні виховні моменти поняття «відповідальності». Тобто буде забезпечено лише обов’язок дотримання загальноприйнятих суспільних норм. А він визначає лише мінімальні можливості юридичної відповідальності. Дотримання обов’язку не забезпечує повну правомірну поведінку в суспільстві та створює обсяг форм поведінки, яких необхідно дотримуватися. Тобто підкреслюється, що для реального застосування відповідальності треба не лише «створити» модель правомірної поведінки, а й законодавчо оформити цю модель в правових нормах, законах. Доводиться той факт, що саме узагальнення в правових нормах надає суспільним правилам правомірної поведінки юридичного змісту. Тобто підкреслено дієвість використання дуалістичної моделі при розгляді підходів до визначення юридичної відповідальності для сучасної державно-правової моделі України.Основною метою статті є узагальнення теоретичних напрацювань вітчизняних науковців у сфері теорії держави й права щодо питання правової природи категорії «юридична відповідальність», а також з’ясування йтипологізація основних наукових підходів та концепцій досліджуваної категорії права.
A Preliminary Bibliography of Polish Publications Concerning the Dead Sea Scrolls (from 1947 to the Spring of 2022)
Authors: Klukowski Michał
Published: August 2023

This publication presents a preliminary bibliography of material on the Dead Sea Scrolls for the years 1947–2022 (spring), which includes only Polish authors’ works which were published. The bibliography has been divided into four parts. The first part gives a list of recent Polish bibliographies, the second one contains monographs and collective works, the third one comprises book chapters and articles appearing in collective works, and the fourth part – papers published in periodicals. The entire work is preceded by a list of abbreviations.
Dylematy automatycznego podejmowania decyzji w postępowaniu administracyjnym – uwagi na tle art. 14 § 1b Kodeksu postępowania administracyjnego
Authors: Wilbrandt-Gotowicz Martyna
Published: August 2023

Problematyka automatycznego podejmowania decyzji administracyjnych wywołuje wiele wąt­pliwości związanych z regulacją podstaw prawnych takich rozstrzygnięć oraz zapewnieniem odpowiednich gwarancji procesowych stronom. W doktrynie brak jest zgodnych ocen co do interpretacji treści art. 14 § 1b Kodeksu postępowania administracyjnego przewidującego możliwość załatwiania spraw z wykorzystaniem pisma generowanego automatycznie. W opracowaniu, przy zastosowaniu metody dogmatycznej dokonano analizy i oceny tej regulacji pod kątem możliwości wydawania decyzji automatycznie przy użyciu sztucznej in­teligencji oraz ich wpływu na pozycję prawną jednostki. Przedstawiono również postulaty dotyczące regulacji trybu algorytmicznego podejmowania decyzji jako odrębnego trybu postępowania jurysdykcyjnego.
SOIL CHEMISTRY, PHYTOCHEMISTRY, AND GC-MS PROFILES OF MORINGA LEAVES (Moringa oleifera ) AS AN ANTIFATIGUE CANDIDATE FROM GEOTHERMAL, COASTAL, AND URBAN AREAS IN ACEH BESAR DISTRICT AND BANDA ACEH MUNICIPALITY, INDONESIA
Authors: Candra Aditya , Fahrimal Yudha , Yusni  , Azwar  , Dilla Santi Tahara
Published: August 2023

Soil chemical components from different locations produce different macro-micro nutrients, phytochemicals compounds, and biological activities of the plant. This study aims to see whether soil chemistry from three different areas namely coastal, geothermal, and urban areas affect the phytochemical components and chemical compounds contained in Moringa (Moringa oleifera) leaves Soil chemical analysis showed that the coastal area had the highest macro-micro nutrients and the best phytochemical and chemical compounds of moringa leaves than those of the other two locations. The moringa leaves phytochemical compounds of the coastal area consisting of alkaloids, saponins, flavonoids, steroids, and phenolics. The GC-MS profile of moringa leaves from the coastal area contained 28 compounds, a geothermal area of 27 compounds, and an urban area of 24 compounds. Of all these chemical compounds, there are six similarities with the highest order namely Linolenic acid, 9,12,15- octadecatrienoic acid, Ethyl ester, Vitamin E hexadecanoic acid, Phytol, and neophytadiene. In conclusion, Moringa leaf from the coastal area has the highest concentration of soil chemical components, phytochemicals, and a number of compounds.
THE ROLE OF PLANT EXTRACTS IN THE REPAIR OF Rattus Norvegicus MANDIBULAR ALVEOLAR BONE IN A PERIODONTITIS MODEL
Authors: C. Lestari  , E. Darwin  , D. P. Putra  , N. Suharti  , B. A. Gani
Published: August 2023

The evaluated herbs plants (α-Mangostin, usnic acid, Piper betle L, and Daemonorops draco) have potency in the alveolar bone repair of mandibular on the periodontitis modeling. Its herbs were evaluated with the flavonoid and phenolic, and ionic values identified by a multi-tester meter. Mol-inspiration software was used to calculate the miLogP value of -mangostin and usnic acid. The evaluation of alveolar bone repair is based on H and E staining profiles of osteoblasts and osteoclasts. The α-Mangostin and Piper beetle L had higher total flavonoid and phenolic concentrations than usnic acid and Daemonorops draco. Based on the miLogP value, usnic acid has better absorption than α-mangostin. The ionic amounts of dissolved Oxygen, conductivity, and total dissolved solids have correlated with osteoblast and osteoclast expression in the bone repair process. The herbs extract can increase the stimulation to produce osteoclast and stability in 7 and 14 days. The ionic values, flavonoids, and phenolic totals of herbs affect the mandibular alveolar bone repair, which is marked to increase the new bone formation (osteoblast) and bone resorption (osteoclast).
SYNTHESIS AND CHARACTERIZATION OF A NEW GRADE(NP-K) FERTILIZER FORTIFIED WITH HEPTAMICRONUTRIENT MATRIX FOR SUPERIOR PLANT GROWTH
Authors: Rao G. N. V. Mohan , Venugopal N. V. S.
Published: August 2023

An evolving approach to agricultural innovations and effective farming practices are key issues of modern agriculture. New-graded fertilizers have an important role in the present agricultural yield advances. Without the application of fertilizers, the soil would be exhausted and it affects the growth of plants. Micro-nutrients are essential for various plant growth and development processes such as protein synthesis, fruiting, flowering etc. Herein we describe a new N-P-K fertilizer fortified with seven micronutrient matrixes. The author synthesized a 100% water soluble 14-14-14 graded fertilizer with seven micronutrients (14-14-14-with 0.5% Zinc, Manganese, Iron, magnesium, & copper, 0.2% Molybdenum & Boron). The proposed fertilizer was analyzed by using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). The higher chloride content in either soil or fertilizer leads to less crop yield. The proposed fertilizer chloride content is less than the existing different grades of fertilizers available in the market. The physical properties such as percentage of moisture, pH, conductivity, and critical relative humidity were determined and these properties showed better results as compared to other graded fertilizers.
SYNTHESIS, In-vitro CYTOTOXICITY AND IN SILICO INVESTIGATIONS OF QUINAZOLINONE INTEGRATED CHALCONES: AS NOVEL POTENTIAL DUAL-TARGETING ANTICANCER AGENTS TO TREAT LUNG CANCER AND COLORECTAL CANCER
Authors: Arora P. K. , S. Kumar  , Bansal S. K. , Sharma P. C.
Published: August 2023

The present study focuses on the synthesis of some 2-methoxyphenylquinazolin-4-one incorporated chalcone hybrids to evaluate their cytotoxic potential by MTT assay, and their affinity to bind with T790M mutated epidermal growth factor receptor (EGFR; protein data bank Id: 5Y9T) and G12D mutated Kirsten rat sarcoma (K-RAS; protein data bank Id:4EPT) by molecular docking (auto dock-4) by employing validated docking parameters. Against the lung cancer cells (A549), except C7 (IC50: 48.22 g/ml), the other title compounds exhibited more cytotoxicity (IC50 16.88g/ml to 33.98g/ml) than the erlotinib (reference). Against the colorectal cancer cells, the compound C4 (IC50: 9.74 g/ml) exhibited more cytotoxicity than the reference (IC50: 16.13 g/ml). For the normal cell lines (Vero), the compound C1 (IC50 27.88g/ml) is less toxic to normal cells, than the reference. The title compounds can be a boon for the development of smart anticancer drugs with dual target virtue
In-silico STUDIES OF UNIQUE SCHIFF BASE OF BENZIMIDAZOLE DERIVATIVES AS ANTICANCER AGENTS
Authors: Jyoti  , Ghosh N. S. , I. Rani  , S. Mujwar  , B.K. Dey
Published: August 2023

Accumulating synthetic pesticides in the living system has brought about several critical alerts from researchers as it interferes with the essential processes in the body. Metal oxide nanoparticles possess suitable properties including band gap and have played an important role in the photocatalytic degradation of toxic chemicals in wastewater and the environment under natural solar radiation. This research aims at the photocatalytic degradation of Type II Pyrethroid Pesticide (Lambda-cyhalothrin) in wastewater and agricultural runoff using Zinc Oxide Nanoparticles. The synthesized ZnO Nanoparticle (NP) was ascertained by characterization using XRD for material crystallinity and crystallite size, SEM, and particle size analysis for surface morphology and size. The EDAX spectra confirmed the presence of Zinc elements and showed that the synthesized zinc oxide nanoparticles were pure. The degradation experiment was conducted under natural solar irradiation. The initial and final/equilibrium concentration of Lambda-cyhalothrin residue were determined using High-performance liquid chromatography (HPLC) followed by computation of degradation capacity. Photocatalytic degradation of LCY was successful following the application of Zinc oxide NPs as nanocatalysts with an efficiency of about 87% as compared to the control. The synthesized Nanoparticle was found to degrade a large percentage of Lambda-cyhalothrin residue in wastewater. Exploiting its application in the remediation of pesticides in agricultural runoff may be crucial at this point.
EXPERIMENTAL STUDY OF THE EFFECT OF SURFACTANTS AND WATER-CEMENT RATIO ON ABRASION RESISTANCE OF HYDRAULIC CONCRETES
Authors: Moldamuratov Zh. N. , Ussenkulov Zh. A. , Yeskermessov Zh. E. , Shanshabayev N. A. , Bapanova Zh. Zh. , Nogaibekova M. T. , Joldassov S. K.
Published: August 2023

The effect of surfactants and water-cement ratio on the abrasion resistance of hydraulic concrete are presented. A series of laboratory tests and field surveys of hydraulic structures were carried out to determine the effect of various factors on the wear resistance of hydraulic concrete to abrasive effects. The basic studies of abrasion of mortar and concretes were carried out at the Portland cement of the Shymkent plant without active mineral and filler additives with activity in 28 days 462 kg/cm2 , a specific surface area of 2740 cm2 /g. In addition, Portland cement from the Karaganda plant was used, with an activity of 28 days 431 kg/cm2 , and a specific surface area of 3450 cm2 /g. The presence of dependencies of the abrasion of concrete on several factors was established: water-cement ratio and strength, the type of filler, the fineness of cement grinding, the age of the samples, the use of surfactant additives, and the method of laying
STABILITY INDICATING METHOD DEVELOPMENT OF RPUPLC, VALIDATION OF SIMULTANEOUS QUANTITATION OF BUPIVACAINE and MELOXICAM IN PURE AND FORMULATION
Authors: Rani J. David Blessing , Deepti C. Asha
Published: August 2023

An easy, accurate, and precise RP-UPLC was established and also validated for simultaneous quantitation of Bupivacaine and Meloxicam in the formulation as well as in pure form. An acceptable separation of Bupivacaine and Meloxicam was shown by the developed technique Bupivacaine and Meloxicam retention times were 1.359 min. and 3.687 min. correspondingly. From regression equations, LOQ and LOD were obtained and observed to be 0.2ppm and 0.6ppm - Bupivacaine, 0.06 and 0.0 I 8ppm - Meloxicam, respectively. Stability studies of the injectable dosage form under forced degradation conditions of acid, alkali, peroxide, thermal, hydrolysis, and ultraviolet rays showed that the technique was particular without interferences from any type of possible contaminations that might form over the shelf life. The newly established RP-UPLC technique was stability indicating, accurate, rapid, and sensitive, for active pharmaceutical ingredients and pharmaceutical dosage forms
The Effect of Occupational Health and Safety Education on Hazelnut Agriculture Workers' Knowledge Levels Related to Physical and Ergonomic Hazards
Authors: TİRYAKİ Oğuzhan , ÇAN Gamze , TOPBAŞ Murat , BEYHUN Nazım Ercüment
Published: August 2023

Objective: The study aimed at identifying dangers and risks encountered by hazelnut farm workers and exploring the effect of occupational health and safety training about hazelnut farming upon the workers’ knowledge level.

Materials and Methods: In this research, which was conducted as an intervention study, the pre-test post-test single-group research pattern was used. Training and brochures were given to 60 hazelnut agriculture employees selected using a random sampling method after the pretest. The change in the current knowledge score was examined statistically with the last test application two weeks later.

Results: 53.3% of the participants were male and their average age was 43.0±14.4 years. 60.0% of the participants stated that they had accidents while they were engaged in hazelnut farming and 71.7% of them did not have any training about occupational health and safety previously. Participants’ score of knowledge about physical dangers and risks as to occupational health and safety was 62.7±17.8 before the training while it significantly increased to 79.3±16.3 after the training. It was seen that after the training held; having a previous training, having high educational status, having no accidents previously and being at a young age affected post-test scores significantly.

Conclusion: In the study, it was explored that hazelnut farming workers in Trabzon Province lacked knowledge about physical and ergonomic risks in relation to occupational health and safety. For the trainings of the workers; universities, provincial and district directorates of agriculture and agriculture cooperatives can be used.
Molecular Study of Human Mammary Tumor Virus in Iraqi Women with Breast Cancer
Authors: Mohsin Tamarah y. , Al-Faham Mohammed A. , Al-Hadithi Waleed K. , Pogo Peatriz G.
Published: August 2023

Background: Earlier reports related the presence of Mouse Mammary Tumor Virus -like gene sequences to human breast carcinoma. Mouse Mammary Tumor Virus -like gene is a retrovirus, namely, a virus containing reverse transcriptase which transcript its RNA to DNA in a process that enables genetic material from the retrovirus to become a part of the genes of an infected cell permanently. The virus that found in women was designated as Human Mammary Tumor Virus by the authors, who have investigated the presence of Human Mammary Tumor Virus sequences in a many human breast tissues and in many countries.
Objectives: Detect HMTV genome in Iraqi women of breast cancer.
Patients and Methods: Formalin Fixed, Paraffin Embedded Tissues were collected from 50-breast cancer women with their age range (23-82 years) compared to 5 normal breast tissues as a control group.  DNA was extracted from and by Nested PCR, using specific primers for amplifying Envelop gene for HMTV were taken in Jovac Center in Amman/Jordan.
Results: There were no detected signals for HMTV in study cases.
Conclusions: The absence of HMTV DNA in breast tissues cancers needs a large sample size to correlate HMTV with breast carcinoma.
Oxidative Stress and Some Liver Functions Parameters in Patients with Symptomatic Cholelithiasis
Authors: Ridha Nibrass M. , Taher Mohammed A.
Published: August 2023

Background : Gallstone disease is one of a common surgical problem and one of the most common gastrointestinal diseases throughout the world but its pathogenesis remains unclear. Many theories have been put forward to explain the mechanism of stone formation. The living organism has enzymatic and non-enzymatic antioxidant systems neutralizing the harmful effects of the endogenous oxygen free radicals products. Under certain conditions, the oxidative or anti-oxidative balance shifts towards the oxidative status as a result of increase in oxygen free radicals and/or impairment in antioxidant mechanism.
Objective :To evaluate the oxidative stress markers (total antioxidants capacity and malondialdehyde) and some liver functions parameters (aspartate aminotransefrerase , alanin aminotranseferase , alkaline phosphatase , total serum bilirubin )in serum of patients with gallstone disease and in control group.
Patients & Methods : The study group included 75 patient with gallstone disease and 33 age- and sex-matched healthy volunteers as control group. Antioxidative status of serum was evaluated by measuring total antioxidant capacity . serum: malondialdehde , aspartate aminotranseferase , alanine aminotransferase , alkaline phosphatase, and total bilirubin, were all measured in serum of patients with gallstones and controls.
Results : There was a significant increase(P<0.05) in serum: malondialdehyde, alkaline phosphatase , alanin aminotranseferase ,aspartate aminotransefrerase , total serum bilirubin levels in  patients with symtomatic gallstones compared to healthy controls. The study also showed  that there was  a significant decrease in serum total antioxidant capasity (P<0.05) in the patients compared to control group .
Conclusion : The present study results indicated that  patients with gallstones may have been exposed to oxidative stress . change in liver functions parameters  was also seen in serum of patients compared to controls . these findings  may provides insights and helps in understanding the various biochemical alterations undergoing in the gallbladder  responsible for stone formation and would be helpful in developing strategies for the treatment and prevention of gallstones.
Redes que cuentan. Revisión sistemática sobre el bienestar subjetivo y el apoyo social percibido en la adolescencia
Authors: Laino Noelia
Published: August 2023

El siguiente artículo presenta una revisión bibliográfica en torno a los constructos bienestar subjetivo y apoyo social percibido. La búsqueda se realizó en Google Scholar y se consideró que los mismos fuesen trabajos presentados en revistas de prestigio académico. Además, se pesquisaron algunas investigaciones que establecían relaciones entre dichos conceptos en la adolescencia. El trabajo se realizó en el marco de una propuesta evaluativa para la materia Psicología de la Salud, cuyo eje se centra en el abordaje de conceptos propios de la Psicología Positiva. En este sentido, resulta de interés señalar que dicha rama de la psicología propone el estudio de aquellos factores que promueven y potencia el funcionamiento psicológico óptimo. Se contrastaron definiciones conceptuales en torno al bienestar subjetivo y apoyo social percibido, reseñando posibles instrumentos de medición psicométrica para ambos conceptos. Por último, se observó una dificultad para encontrar artículos que relacionaran ambos constructos en torno a dicha población, planteando algunas preguntas al respecto de la adecuación de los instrumentos.
Plato in East Asia?
Authors: Kim Hyun Jin , Horesh Niv
Published: August 2023

Shadi Bartsch in her recent publication Plato goes to China (2023) has argued that Plato and the Greek classics have had an out-sized impact on Chinese politics and intelligentsia. This article, while sympathetic to her approach, argues that there is little evidence that Plato and the Greek Classics have exerted any direct influence on Chinese politics. Rather it argues that what influence Plato has had on China is actually indirect via a pre-war national socialist Japanese filter. In pre-World War II Japan Plato was fetishized as the ancient source of western socialist and communist thinking. Radical extremists such as Kita Ikki and Kanokogi Kazunobu created a new ideology that mingled aspects of Platonism with socialism and Japanese nationalism. They hoped thereby to create a modern-day Platonic utopia for the East Asian races (and for the Japanese in particular). This article examines how this modern-day “version” of Platonism with “Asian” characteristics impacted on pre-war Japan and modern East Asia as a whole.
The Path to Democracy: A Critical Evaluation of the Impact of Region on the Democratic Process in the Western Balkans
Authors: Kashami Ilda , Curi Arjan
Published: August 2023

Purpose: The present research is placed within the strand of studies on the quality of democracy and state-building in the Western Balkans (WB). We aim to explore the impact that both variables have on each other and on fostering democratic values in the specific given region. Methods: The method implied for the present work is desk research based on cohort studies or the path of Democratic evolution of the region. Data results, scored by MAXQDA software for desk and cohort-comparative research, comparing the World Government Index (WGI), the Bertelsmann Stiftung Index (BTI), and Freedom House reports for trends and predictions for the WB in a 30-year continuum and democratic transition, from 1992-2022. Results: Descriptive statistics revealed a linear distribution of both variables in all the 6WB countries (M=1.33; Mtot=36.33; SD=22.017) meaning the same probability of partial democratic scores in all the Region’s countries. Pearson correlation data revealed that there is a relation between the two variables (rw=.642; p<0.05). Regressive analysis revealed a good variability and Rsquare=.612 indicating that both variables encountered of a total of 95% of the total variance and stability. Linear regression also revealed a good influence between the 6WB region and their democratic status, confirming our primary assumption (R=.642; Sig2. p=0.63<0.05). Conclusions: One of the detrimental addresses of the present work is related to the conceptions of “Democracy”, “Geolocalisation”, “Rule of Law” and “Political Stability” and their impact on the policy effectiveness of the WB. In the end, the authors recommend a broad technical review of the Region’s Democratic Values and evolution achievements in the light of adherence to the European Union Value market.
Can Artificial Intelligence help a clinical laboratory to draw useful information from limited data sets? Application to mixed connective tissue disease
Authors: Bertin Daniel , Bongrand Pierre , Bardin Nathalie
Published: August 2023

Diagnosis is a key step of patient management. During decades, refined decision algorithms and numerical scores based on conventional statistical methods were elaborated to ensure optimal reliability. Recently, a number of machine learning tools were developed and applied to process more and more extensive data sets, including up to millions of items and yielding sophisticated classification models. While this approach met with impressive efficiency in some cases, practical limitations stem from the high number of parameters that may be required by a model, resulting in increased cost and delay of decision making. Also, information relative to the specificity of local recruitment may be lost, hampering any simplification of universal models. Here, we explored the capacity of currently available artificial intelligence tools to classify patients found in a single health center on the basis of a limited number of parameters. As a model, the discrimination between systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD) on the basis of thirteen biological parameters was studied with eight widely used classifiers (including logistic regression, support vector machine, nearest neighbor classifier, random forests and neural networks). A retrospective study including 44 patients (34 SLE, 10 MCTD) was conducted in Marseilles hospital organization. The best area under ROC curve yielded on test sets with classifiers using all 13 parameters was 0.83 ± 0.03 standard error and 0.86 ± 0.02 SE with 5 selected parameters. It is concluded that classification efficiency may be significantly improved by a knowledge-based selection of discriminating parameters.