bluuebunny/crossref_metadata_2025 huggingface dataset:
Confidence is influenced by evidence accumulation time in dynamical decision models
Authors: Hellmann Sebastian , Zehetleitner Michael , Rausch Manuel
Published: November 2023

Confidence judgments are closely correlated with response times across a wide range of decision tasks. Sequential sampling models offer two competing explanations for the relationship between confidence and response time: According to some models, decision time directly influences confidence. Other models explain the correlation by linking subjective confidence computation to the decision process dynamics. In previous model comparisons, drift diffusion-based confidence models that do not explicitly consider decision time in the computation of confidence, provided superior model fits compared to race models that directly included decision time in the internal computation of confidence.In the present study, we present support for the assumption that confidence explicitly takes decision time and post-decisional accumulation time into account. We propose the dynamical visibility, time, and evidence (dynaViTE) model, an extension of the dynamical weighted evidence and visibility (dynWEV) model. DynaViTE assumes that confidence is not solely based on the final amount of accumulated evidence but explicitly includes time in the computation of confidence. Model comparisons using four previously published data sets with different perceptual decision tasks showed a good fit of dynaViTE, indicating that the relationship between confidence and response time is not only due to the close link in the accumulation process but also to an explicit inclusion of time in the computation of confidence.
Conceptualizing burnout from the perspective of parents of children with complex care needs
Authors: Patty Nathalie , van Meeteren Karen , Verdonk Minke , Ketelaar Marjolijn , Schuengel Carlo , Willemen Agnes M.
Published: November 2023

Abstract Objective: The purpose of this study was to investigate how parents of children with complex care needs conceptualize burnout from the perspective of parents themselves. Methods: We conducted semi-structured interviews with 38 parents, selected for maximal variation in parental, child, and family characteristics. Inductive thematic analysis was employed. Results: Burnout was conceptualized as encompassing three themes: having a reoccurring long-term nature, commencing with symptoms of stress progressing into exhaustion, and ending in a survival mode wherein parents worked hard to project an image of everything being well and under control (fighting) while distancing physically and emotionally from others and themselves (fleeing). Conclusion: Burnout involves specific aspects of caregiving and parenting, such as long-term responsibility for the child, which cannot be relinquished. Furthermore, burnout may also be ‘hidden’: not always showing to the outside world, which requires extra attention and vigilance among parent’s informal and formal networks. Awareness of the various interpretations of the term may foster constructive communication. Innovation: Focusing on parents' individual experiences has illuminated new aspects of burnout. By purposively sampling a variety of parents of children with complex care needs, a broader understanding of the meaning of the term ‘burnout’ from the perspective of parents was achieved.
Drivers of land use land cover change and intensity analysis of land transformation in the moist semi-deciduous forest zone of Ghana: Case of Bobiri Forest Reserve and its environs
Authors: Dembele Famoussa , Guuroh Regenald Tang , Ansah Padmore Boateng , Asare Da-Costa Boakye Mensah , Biney Ernest , Adu-Bredu Stephan
Published: November 2023

Understanding land cover transformation over time and space is crucial for comprehending ecological challenges, particularly in environmentally vulnerable areas. In Sub-Saharan Africa, the demand for fuel, food, and fibre is expected to significantly expand croplands, resulting in the degradation of natural ecosystems. This research presents a spatiotemporal analysis of land-cover change in the Bobiri forest and its surrounding areas in Ghana's moist semi-deciduous forest zone. The study’s main objectives were to identify the drivers of land-cover change, and to analyse the intensity of land transformation from 1986 to 2022 in the study area. The methodology used measured land-cover changes at different levels, including intervals, categories, and transitions. The findings indicate that the annual rate of land change was higher from 1986 to 2007 (1.64%) compared to the period from 2007 to 2022 (1.04%). Additionally, the analysis at the category level reveals that the increase in cropland and non-vegetated areas during both time intervals was higher than the uniform intensity. The analysis at the transition level suggests that most of the cropland gains originated from non-vegetated areas during both periods. There is also evidence of localized increases in closed forests, likely due to afforestation policies implemented by the Ghanaian government. However, overall, there has been a decline in closed forests over the entire timeframe, with an annual rate of change of -1.25%. This study contributes valuable data for enhancing our understanding of the scale and direction of land-cover change, which is essential for developing policies aimed at mitigating the impact on local livelihoods and the environment at national and sub-national levels.
Patterns of genetic diversity and structure of Eucalyptus grandis breeding population in Kenya: Implication for genetic improvement
Authors: Omondi Stephen
Published: November 2023

Eucalyptus grandis is an important commercial plantation tree species providing raw materials for many industrial products. The species is widely cultivated in the tropics because of its wood quality and adaptability to wider climatic conditions, and is currently undergoing genetic improvement in Kenya for first growth and superior wood quality. Generally, tree breeding operations involve recurrent selection of genetically superior individuals, which potentially alters genetic diversity in the breeding populations. It is therefore essential to determine the genetic diversity of breeding populations to support improvement programmes. We evaluated the genetic diversity and structure of 250 individuals from five first generation breeding populations of E. grandis in Kenya using seventeen nuclear microsatellite markers. The microsatellite markers revealed an average polymorphic information content (PIC) of 0.826, confirming their suitability for discriminating the genotypes and populations. High genetic diversity was found within all the breeding populations. The number of alleles per population (Na), observed heterozygosity (Ho), expected heterozygosity (He), and Shannon’s information index (I) averaged at 6.9, 0.801, 0.821, and 1.662, respectively. The findings indicate that the breeding population has high levels of genetic variability offering possibilities to develop advanced generation breeding programmes for the species. Furthermore, lower fixation index (F) was detected in the seed trees (-0.101) than their offspring (0.121), suggesting selection against inbred individuals between seedling and adult stages. The genetic differentiation among the breeding populations was low and non-significant (Rst = 0.017; P = 0.117), indicating close genetic relationship among the germplasm used to establish the breeding populations. The studied breeding populations are viable for genetic improvement; however, new genetic infusions are recommended to expand the gene pool in the subsequent breeding generations.
Genomic prediction across generations in a Eucalyptus grandis breeding population
Authors: Rodríguez Raffo María Virginia , Dutour Joaquín , Cappa Eduardo Pablo , Quezada Marianella
Published: November 2023

Forest genetic breeding programs are intricate, long-term, and costly processes. To overcome these limitations, genomic selection emerges as an important tool to enable shorter cycles through early selection and to increase breeding value accuracies. Genomic selection is based on a predictive model derived from a training population (TP), integrating genotypic, phenotypic, and pedigree data to predict breeding values on selection candidates (SP) based on genomic information. As breeding generations advance, the relatedness between the TP and SP decreases, with the reduction of the prediction ability. The objective of this study is to optimize the TP for a Eucalyptus grandis breeding population across four consecutive generations (G1, G2, G3, and G4). A population of 66,221 individuals (from four generations) resulting from cross-breeding and open-pollination were measured for diameter at breast height (DBH) and total tree height (HT). Wood quality traits were determined for 16,068 trees and assessed using Near-Infrared Spectroscopy (NIRS). A total of 3,221 individuals from the four generations were genotyped using the EUCHIP60K or the Euc72k Axiom Eucalyptus Genotyping Array. We compared the prediction ability using all the previous generations in the TP as opposed to only including the previous generation. Single-step GBLUP (ssGBLUP) models were evaluated in three phenotypic traits: volume, pulp yield, and wood density. The inclusion of all the previous generations provides a higher predictive ability of 0.40 and 0.54 for volume and pulp yield, respectively, in the target generation G4. When only the previous generation G3 was used as a TP, no significant differences in predictive abilities were observed for volume, and there was a slight decrease in pulp yield. In contrast, for wood density, the predictive ability was highest (0.37) in the G4 when the model was training with only the G3, while including all preceding generations decreased to 0.33. Our results provide insight into the optimization of TP across generations, encouraging the implementation of genomic selection in the Eucalyptus breeding program.
Evaluation of clones of Eucalyptus planted in an experimental plot for Forest Landscape Restoration in Paraguay
Authors: Paez Tatton Fernando José , Quevedo Maria Laura , Gamarra Ruiz Diaz Lila Mabel , Perez de Molas Lidia Florencia , Silva Imas Haroldo Nicolas
Published: November 2023

The adoption of strategies involving the combination of Eucalyptus plantations with native species emerges as an effective alternative to mitigate the issues of deforestation, degradation, and fragmentation affecting native forests. Eucalyptus, in this context, presents itself as a species that offers a rapid economic return, making it an appealing resource for private landowners aiming to carry out land restoration processes. The aim of this study was to compare the growth in diameter at breast height, diameter at collar height, crown coverage area, and height of the Eucalyptus urophylla S.T. Blake × Eucalyptus grandis W. Hill (clone i144) and Eucalyptus urophylla S.T. Blake × Eucalyptus camaldulensis Dehnh. (Clone vm01) hybrids. The study was conducted in the district of Hernandarias, Alto Paraná Department, Paraguay. It was structured into 5 blocks and 2 treatments randomly distributed. Both treatments were selected for this study, with the first treatment consisting of a strip of eucalyptus for timber purposes, and the second treatment serving energy purposes. The design of each experimental unit comprised two major strips, one for conservation and the other for production. The focus of the study was on the second strip, which included 32 trees per experimental unit on treatment 1, and the second treatment, with 44 trees, covering an area of 1080 m2 per unit. The parameters evaluated for this study were as follows: diameter at collar height (DAC), total height (Ht), Diameter at breast height (DAP), and crown coverage area (ACP) over a 24-month plantation period. Statistically, no significant differences were found in the analyzed variables; on average, it was determined that the means were 1167.3 cm, 11 cm, 3.9 m2, 132.3 cm for Ht, DAP, ACP, and DAC, respectively.
Indicators of efficiency in operational crosses of Eucalyptus dunnii and hybrids in Montes del Plata: Current progress and challenges
Authors: Heberling Mónica , Pereira Silvia
Published: November 2023

One of the main goals of a tree breeding program is to increase forest productivity, adaptation and profitability of forest plantations. Eucalyptus dunnii is a main species used for pulp production in Uruguay. Montes del Plata (MdP) is one of the largest forest companies in Uruguay and has been focused on the development, testing and deployment of E. dunnii clones to establish commercial plantations in Uruguay. This poster refers to the generation of control-pollinated families, as the starting point of MdP clonal strategy. Control pollination (CP) is a tool in genetic breeding programs that enables to recombine selected genotypes with desired traits to maximize gain in the medium to long term. The selection trait for pulpwood objective is tons of cellulose per tree (ADt); consequently, growth, frost tolerance, health, and wood properties are relevant for parent selection. Ongoing work shows a fruitfully performance of E. dunnii. In the south-east region of Uruguay the species have one flowering period per year, with an average flowering time occurring between the last fortnight of February and the first half of May. Developed protocols for pollen harvesting and methods for crossing are used. The survival of pollinated flowers resulting in fruits has shown to vary with parental species. Average survival rates are 20 to 35%. The main loss of crop happens during the first 4 months after pollinating, weighting —in average— a loss of 40% of the pollinated flowers. The species fruit crop occurs one year after CP. The number of seed per fruit varies with the parental species. E. dunnii × E. dunnii crosses yield in average 6.4 seeds per fruit. However, we have seen a reduction in seeds per fruit in hybrid crosses, where E. dunnii is pollinated with another species, mostly E. globulus, E. grandis and E. dorrigoensis. Seed crops are sawn in the nursery and start an individual clonal selection based on rooting protocols. Clones that fulfill the rooting constraints go to field trials. This is presented in another poster proposal. Main challenges for the future are to maintain a wide genetic diversity in the breeding population, early flowering, and continuous improvement on CP techniques.
Classifying health issues in Eucalyptus miniclonal gardens in Uruguay
Authors: Martínez Gonzalo , Hirigoyen Andrés , Alonso Raquel , Tiscornia Susana , Lupo Sandra
Published: November 2023

Clonal propagation is extensively used in the Eucalyptus pulp industry in Uruguay. Mother plants are maintained in clonal minigardens and they constitute the source of cuttings that are harvested continuously and sent to shaded greenhouses for rooting. Environmental conditions within the minigarden are optimized for plant growth, but such conditions can also promote the emergence of pests and diseases which can affect the mother plants and impair cutting production. However, comprehensive studies on health status within minigardens are scarce in the country. We carried out a seasonal survey on three clonal minigardens along the country to check for epidemiological patterns connected to the time of the year, the conditions within the clonal garden and the genetic material in propagation. We visited each minigarden at least once per season during 2019 and the beginning of 2020. During each visit, we inspected all the mother plants along three transects (two on the edges and one in the centre of the minigarden). We counted the number of plants with symptoms of disease and of insect attacks, and collected samples of affected plants for further identification in the laboratory, if necessary. We looked for a way to classify nurseries and species all together, according to the incidence of the different health issues surveyed. Thus, the dataset obtained from the surveys was assessed under different classification algorithms based on machine learning: neural networks, discriminant analysis models, classification regression tree, support vector machine, and random forest. We observed attack by arthropods such as mites, whiteflies, scales and aphids and caterpillars. We also recorded powdery mildew and disease symptoms such as dead plants and dry shoots. The different materials assessed during the survey belonged to E. grandis, E. dunnii, and E. grandis × E. globulus hybrids. The most common symptoms observed in all the minigardens and throughout the entire survey period were powdery mildew and damage from mites. The support vector machine model performed best, being able to classify the dataset with an accuracy of 76%. We discuss the relevance of these findings within the context of miniclonal garden health management.
Identification of cold stress-responsive microRNAs and mRNA in Eucalyptus grandis
Authors: Farias Joaquina , Basile Patricia , Giorello Facundo M.
Published: November 2023

MicroRNAs (miRNAs) are a class of non-coding endogenous small RNAs that play a crucial role in plant growth, development, morphogenesis, signal transduction, and stress response. miRNAs negatively regulate gene expression at post-transcriptional level, causing translational repression or/and transcript degradation. The role of miRNAs in understanding gene expression reprogramming under different stress types has been pointed out. Low temperature is an important factor limiting the growth and distribution of plants. Under cold stress, plants attempt to maintain homeostasis and acquire cold acclimation, which involves extensive gene expression and metabolism reprogramming. Particularly, cold stress limits the distribution and productivity of Eucalyptus plantations, significantly affecting the survival and yield of seedlings. Despite the consensus on the relevance of miRNAs in regulating gene expression in plants and Eucalyptus's huge importance for the forest industry worldwide, information on miRNAs in Eucalyptus is still very scarce. In this work, we studied the miRNA and mRNA response to cold stress in E. grandis, one of Uruguay's most widely planted Eucalyptus species. Since seedlings are more susceptible to chilling injury, we subjected 3 different genotypes of seedlings to a cold shock followed by a 12-hour recovery phase at 25°C, analyzing a total of 4 treatments (G1: control, G2: 12 hours at 4°C, G3: 24 hours at 4°C, and G4: 24 hours at 4°C + 12 hours at 25°C). Cold treatment was evaluated measuring the electrolyte leakage. The membrane's damage was verified at 12 hours at 4°C, increasing the parameter at 24 hours. The membrane was partially recovered after 12 hours at 25°C, decreasing the electrolyte leakage. Transcriptome analysis showed an increase in the expression of genes belonging to the AP2|ERF family, including the DREB1|CBF genes —a group of genes that control the activation of protection mechanisms under cold stress. Within down-regulated genes, GO terms related to photosynthesis were enriched. Several conserved and new microRNAs were identified, but only a minority changed their expression with cold treatment, among them, the miR828. This microRNA was down-regulated after the cold treatment, which, according to several studies, induces the expression of anthocyanins. Anthocyanin levels are known to increase under different conditions, including cold stress. These results provided data on gene silencing mechanisms in E. grandis and allowed characterizing the response to cold mediated by small RNAs. This data could be potentially used by selection and improvement programs seeking to select clones more tolerant to cold stress.
Ethnomathematics: Utilization and Introduction of Geometry Buildings Using Janur (Coconut Leaf)
Authors: Saputri Dwina Rahayu , Br Ginting Siti Salamah
Published: November 2023

One area of mathematics that requires a good understanding and depiction of abstract concepts is geometry.  Therefore it is necessary to apply realistic learning.  One type of realistic learning is ethnomathematics.  Ethnomathematics is a bridge between mathematics and culture by linking culture and students' everyday experiences.  Traditional crafts that can be lifted are creations from coconut leaves (janur) which can be formed into various kinds of craft creations that contain geometric shapes.  The type of research used in this research is descriptive qualitative research.  Data collection was used through literature and interviews. The results of the research show that creations from coconut leaves (janur) can be geometric shapes that can be used as ethnomathematics objects.  These forms include (1) coins that can be made into hexagons, (2) kerises that have elements of equilateral triangles, right triangles, and parallelograms, (3) diamond bricks that have elements of square geometry lengths and blocks, (4) balls (balans) which have square and cube geometry elements, (5) sinta diamonds which have rhombus geometry elements and rhombus upright prisms. Other geometric elements contained in the janur creations are congruence, angles, and symmetry.

Keywords: ethnomathematics, geometry, coconut leaves.
Yeyunostomía laparoscópica
Authors: Haro Camila , Muniz Nicolás , Mansilla Sofía , Vanerio Madelón , Canessa César
Published: November 2023

La yeyunostomía implica el abocamiento del yeyuno a la piel y se utiliza como vía de nutrición enteral en pacientes con imposibilidad de alimentarse por vía oral; en quienes la gastrostomía no es una opción adecuada. La misma puede realizarse por vía mínimamente invasiva, como percutánea y laparoscópica

 

Ver el video en YouTube

https://youtu.be/QfqX0A62alg?si=RiJBkd0Bz2ueG7Cs
What Has Changed Za Eti Paru Desyatkov Let (‘Over These Two Couples of Decades’) in the Agreement
Authors: Marinova Elena V.
Published: November 2023

The research conducted on Russian written texts studies the phenomenon of the mass use of the plural form of attributes in the case of their agreement with the word form para as part of a quantitative-nominal turn with the meaning of an indefinite quantity. This meaning of the word para is realized when combined with dependent words denoting time periods. The author notes the most frequent constructions with various prepositional-nominals forms of the noun para, in which there are fluctuations in the choice of the grammatical number of the attribute. The research material is media and literary texts in Russian. The sources of the research are the National Corpus of the Russian Language and the electronic media bank Integrum (Media Archive service). The reasons for the speaker's preferential choice of the plural form (za eti paru let) instead of the normative singular are primarily linguistic. The effect of the tendency to semantic agreement and the analogy with the type of agreement implemented in the case of semantically similar turns neskol’ko dney, dva-tri dnya that require an attribute in a plural form belong to them. Extralinguistic factors are also important, and one of them is the reproduction of an error in a text repeatedly reprinted in various media. The study also examines the choice of the numerical form of the predicate with the subject para dney (let, etc.), which, as in the case of the attributes, varies. The author interprets the detected anomalies in the form of unexpressed grammatical markers of gender and case, which are clearly not of a singular nature, as a process of lexicalization of a turn with the word para ‘a few’.
On the Poem by Boris Slutsky “They shot Van’ka, the platoon commander…”. Problems of Understanding
Authors: Shapiro Nadezhda A.
Published: November 2023

The article is devoted to analysis of a poem written by Boris Slutsky. Boris Abramovich Slutsky (1919–1986), Russian poet and a veteran of the Great Patriotic War, is an important figure in the Russian poetry of the second half of the 20th century. The article examines the poem “They shot Van’ka, the platoon commander…” that was not published until the late 80s. While very simple in form, the poem leaves a great deal of room for interpretation of its content. The author intentionally chooses a restrained tone and avoids judgmental vocabulary that could reveal his attitude towards the depicted events. The article attempts to expose the author’s standpoint by means of stylistic analysis (the poem incudes words and phrases from a wide range of stylistic registers: from obsolete words and bureaucratic formulas to colloquial and vernacular expressions, sometimes even deliberately violating grammatical rules) and by examining the text’s important syntactic features. It is argued that Slutsky’s military background is very important for analysis of his poems. During the war he was a secretary at a division prosecution office, later an investigator. Reflection of this experience that the author himself calls “painful and sordid” can be found in his verses.
ОСОБЛИВОСТІ МАРКЕТИНГОВОГО УПРАВЛІННЯ В ТУРИСТИЧНОМУ БІЗНЕСІ
Authors: КАТКОВА Тетяна , МАТЮХ Сергій
Published: November 2023

Сучасні умови господарювання вимагають нових підходів не тільки у плануванні асортименту послуг, але й у формуванні нових підходів до підвищення ефективності діяльності туристичних організацій на основі технологій маркетингу. Доведено, що актуальним має стати формування тенденції до сприйняття маркетингу саме як інструмент управління. Такий підхід дозволить своєчасно виявляти зміну у факторах впливу на діяльність, створювати ефективні комунікації з клієнтами, посилювати конкурентні позиції на ринку.

Метою дослідження є визначення особливостей здійснення маркетингового управління в туристичному бізнесі в сучасних умовах та виявлення факторів впливу на його формування. 

З’ясовано, що роботу туристичної фірми на ринку можна розглядати у кількох аспектах: як роботу державних структур, об'єднань, асоціацій щодо просування свого національного туристичного продукту та залучення туристів; як роботу туроператора з вивчення попиту на створення конкурентоспроможного пакету послуг та забезпечення його збуту; як роботу з продажу туристичних послуг із забезпечення успішної реалізації турів.

За результатами проведеного аналізу обґрунтовано основні напрями роботи маркетингових відділів туристичної організації. У зв’язку з цим досліджено їх специфіку та коло функціональних обов’язків. Зазначено, що при плануванні маркетингових заходів та при розподілі функціональних обов’язків відділу (департаменту) маркетингу слід враховувати тенденції розвитку туризму в Україні.
Postdocs in Russia: Peculiarities of Employment and Incentives
Authors: Skachkova L. S. , Malichenko I. P. , Yakovleva E. A.
Published: November 2023

The article presents the results of the author’s research aimed at identifying the peculiarities of employment of postdocs, a relatively new labor category for the Russian academic labor market. Due to several difficulties associated with forming a sample of postdocs (difficulty in identifying key persons responsible for the development of postdoctoral programs; direct, but not always justified, refusals to provide data, difficulties in identifying potential respondents due to their occupation of various scientific positions in Russian universities), the “snowball” method was used. As a result, the empirical basis of the study was formed based on the results of an online survey of 44 postdocs. As part of the study, tasks related to compiling a socio-economic portrait of a postdoc based on economic, socio-demographic characteristics and indicators of research efficiency, identifying the characteristics of the employment and placement experience of postdocs, objective factors and individual motives for making decisions in the field of choosing postdoctoral programs were solved, as well as diagnostics of tools and channels for young researchers to search for vacancies. The authors distinguish between types of academic mobility (educational and labor) and consider postdoctoral studies as a promising form of external labor academic mobility aimed at attracting and retaining high-potential young researchers planning a long-term career in the academic labor market.

Shifting the emphasis from the inbreeding model of university development (internal labor mobility) to the model of external labor academic mobility of young specialists allows those universities that can effectively manage the flow of academic human capital to receive additional socio-economic preferences and return on investment. There are very few similar empirical studies that analyze the features of the development of postdoctoral institutions in Russia and abroad and are based on quantitative and qualitative data from surveys of direct participants in external labor academic mobility – postdocs, which determines the scientific novelty and practical value of the proposed results.
Demokratie, Hegemonie, Ethik – Ein radikaldemokratischer Versuch zur politischen Philosophie von Martin Luther King, Jr.
Authors: Roske Richard , Weiß David
Published: November 2023

Während Martin Luther King, Jr. als Ikone der Civil Rights-Bewegung in den 1960er Jahren bekannt ist, werden seine Predigten, politischen Reden und Schriften erst in den vergangenen Jahren vermehrt auch als politiktheoretisch fruchtbare Ressource, etwa für demokratietheoretische Debatten, wahrgenommen. In diesem Essay soll sich Kings ‚Demokratietheorie‘ aus radikaldemokratischer Perspektive angenähert werden. Dabei wird deutlich, wie King einen geweiteten Demokratiebegriff vertrat, Demokratisierung außerdem als wesentlich diskursives und ‚identitätspolitisch‘ fokussiertes Projekt verstand. In seinen Reflexionen über die Rolle von Emotionen in der politischen Praxis lassen sich Parallelen zum Begriff einer (radikal-)demokratischen Ethik ziehen. Dieser spezifisch radikaldemokratische Leseversuch kann – trotz der dezidiert theologischen Fundierung Kings politischen Denkens, welche sich nicht vollständig mit postfundamentalistischen Ansätzen versöhnen lässt – sowohl zu einer weiteren demokratietheoretischen Systematisierung von Kings politischer Philosophie beitragen als auch produktive Anknüpfungspunkte für die demokratietheoretische Debatte ausweisen.
Integrative analysis of histone acetyltransferase KAT2A in human cancer
Authors: Li Hua , Li Chun , Yang Lu-Zong , Liu Ji
Published: November 2023

The high incidence of mutations and the crucial roles of KAT2A in cancer development have received increased attention. Nevertheless, a systematic comparison of the heterogeneity and dynamics across different cancer types has not been conducted. Hence, a deep analysis using public databases was performed to clarify the contributions of KAT2A and its correlation with tumorigenesis. The raw data regarding KAT2A expression in cancer patients and healthy controls were obtained from The Cancer Genome Atlas (TCGA). Sexually dimorphic manner, genomic alterations, and expression pattern of KAT2A, as well as the association of the KAT2A with survival, were retrieved from UALCAN, cBioportal, and TISIDB databases. Additionally, the Protein-Protein Interaction (PPI) analysis was conducted using the STRING database. The human protein atlas was used to obtain the staining results of protein levels in cancer and normal samples. The correlation between KAT2A and its potential target drugs was determined using TISIDB and HISTome2. Compared to the normal tissues, CHOL and TGCT tumors presented significantly high KAT2A expression, which was positively correlated with BLCA, BRCA, CESC, CHOL, COAD, ESCA, HNSC, KICH, KIRP, LIHC, LUAD, LUSC, READ, STAD, and THCA. However, no significant difference was detected between normal and tumor tissues for the sex difference pattern of KAT2A expression. The PPI analysis indicated that TADA3, CCDC101, TRRAP, SUPT3H, MYC, TADA2A, and USP22 levels were positively correlated with KAT2A expression, while TADA2B and ATXN7 were negatively correlated. A positive link of KAT2A with cancer isotypes and significant connections of the KAT2A expression to poor overall and disease-free survival were also observed. Further validation was conducted using immunohistochemistry (IHC) staining, qPCR, and Western blot. Some potential HAT inhibitory drugs of KAT2A were also determined, but more work and clinical trials are required before their application.
Cardiac Arrhythmia multiclass classification using optimized FLS-based 3D-CNN
Authors: Pashikanti Rajesh , Patil C.Y. , Shinde Amita
Published: November 2023

Arrhythmia is the medical term for any irregularities in the normal functioning of the heart. Due to their ease of use and non-invasive nature, electrocardiograms (ECGs) are frequently used to identify heart problems. Analyzing a huge number of ECG data manually by medical professionals uses excessive medical resources. Consequently, identifying ECG characteristics based on machine learning has become increasingly popular. However, these conventional methods have some limitations, including the need for manual feature recognition, complex models, and lengthy training periods. This research offers a unique hybrid POA-F3DCNN method for arrhythmia classification that combines the Pelican Optimisation algorithm with fuzzy-based 3D-CNN (F3DCNN) to alleviate the shortcomings of the existing methods. The POA is applied to hyper-tune the parameters of 3DCNN and determine the ideal parameters of the Gaussian Membership Functions used for FLSs. The experimental results were obtained by testing the performance of five and thirteen categories of arrhythmia classification, respectively, on UCI-arrhythmia and the MIT-BIH Arrhythmia datasets. Standard measures such as F1-score, Precision, Accuracy, Specificity, and Recall enabled the classification results to be expressed appropriately. The outcomes of the novel framework achieved testing average accuracies after ten-fold cross-validation are 98.96 % on the MIT-BIH dataset and 99.4% on the UCI arrhythmia datasets compared to state-of-the-art approaches.
BVMHA: Text classification model with variable multihead hybrid attention based on BERT
Authors: Peng Bo , Zhang Tao , Han Kundong , Zhang Zhe , Ma Yuquan , Ma Mengnan
Published: November 2023

Text classification is an important tasks in natural language processing. Multilayer attention networks have achieved excellent performance in text classification tasks, but they also face challenges such as high temporal and spatial complexity levels and low-rank bottleneck problems. This paper incorporates spatial attention into a neural network architecture that utilizes fewer encoder layers. The proposed model aims to enhance the spatial information of semantic features while addressing the high temporal and spatial demands of traditional multilayer attention networks. This approach utilizes spatial attention to selectively weigh the relevance of the spatial locations in the input feature maps, thereby enabling the model to focus on the most informative regions while ignoring the less important regions. By incorporating spatial attention into a shallower encoder network, the proposed model achieves improved performance on spatially oriented tasks while reducing the computational overhead associated with deeper attention-based models. To alleviate the low-rank bottleneck problem of multihead attention, this paper proposes a variable multihead attention mechanism, which changes the number of attention heads in a layer-by-layer manner with the encoder, achieving a balance between expression power and computational efficiency. We use two Chinese text classification datasets and an English sentiment classification dataset to verify the effectiveness of the proposed model.
Effective history and efficient integration for conversational machine reading comprehension
Authors: Zhang Yu , Shen Bo , Zhang Jinglin , Zhang Zhiyuan
Published: November 2023

The task of conversational machine reading comprehension (CMRC) is an extension of single-turn machine reading comprehension to multi-turn settings, to relflect the conversational way in which people seek information. The correlations between multiple rounds of questions mean that the conversation history is critical to solving the CMRC task. However, existing CMRC models ignore the interference that arises from using excessive historical information to answer the current question when incorporating the dialogue history into the current question. In this paper, an effective Question Selection Module (QSM) is designed to select most relevant historical dialogues when answering the current question through question coupling and coarse-to-fine matching. In addition, most existing approaches perform memory inference by stacked RNNs at context word level, without considering semantic information flowing in the direction of conversation flow. In view of this problem, we implement sequential recurrent reasoning at the turn level of the dialogue, where the turn information contains all the filtered historical semantics for the current step. We conduct experiments on two benchmark datasets, QuAC and CoQA, released by Stanford University. The results confirm that our model satisfactorily captures the valid history and performs recurrent reasoning, and our model achieves an F1-score of 83.0% on CoQA dataset and 67.8% on QuAC dataset, outperforming the best alternative model by 4.6% on CoQA and 2.7% on QuAC.
Simulation system of intelligent photovoltaic grid-connected inverter considering fuzzy PI control
Authors: Yang Huailei
Published: November 2023

The grid connected inverter is the core component of the photovoltaic grid connected power generation system, which mainly converts the direct current of the photovoltaic matrix into alternating current that meets the grid connected requirements, playing a key role in the efficient and stable operation of the photovoltaic grid connected power generation system.This paper uses fuzzy PI control model which to improve the performance of intelligent photovoltaic grid-connected inverter to simulate the intelligent photovoltaic inverter system, using mathematical analysis and reasoning methods for model analysis,adopts two-stage three-phase LCL grid-connected inverter, establishes mathematical models in two-phase synchronous rotating and two-phase static coordinate systems, and adopts an active damping strategy based on grid-connected current. Based on existing research and empirical analysis,aiming at the disadvantage of poor dynamic response of repetitive control, an improved repetitive control strategy is adopted, and the controller is analyzed from two aspects of stability and dynamic performance, and the simulation model of photovoltaic grid-connected power generation system is built. Use experimental analysis method to verify the effectiveness of the model in this article,The experimental results show that the simulation system of intelligent photovoltaic grid-connected inverter considering fuzzy PI control proposed in this paper has certain effects.
Unsupervised domain adaptation with local structure preservation for colon histopathological image classification
Authors: Li Ping , Ni Zhiwei , Zhu Xuhui , Song Juan , Liu Wentao
Published: November 2023

The histopathological image classification method, based on deep learning, can be used to assist pathologists in cancer recognition in colon histopathology. The popularization of automatic and accurate histopathological image classification methods in this way is of great significance. However, smaller medical institutions with limited medical resources may lack colon histopathology image training sets with reliable labeled information; thus they may be unable to meet the needs of deep learning for many labeled training samples. Therefore, in this paper, the colon histopathological image set with rich label information from a certain medical institution is taken as the source domain; the colon histopathological image set from a smaller medical institution with limited medical resources is taken as the target domain. Considering the potential differences between histopathological images obtained by different institutions, this paper proposes a classification learning framework, namely unsupervised domain adaptation with local structure preservation for colon histopathological image classification, which can learn an adaptive classifier by performing distribution alignment and preserving intra-domain local structure to predict the labels of the colon histopathological images from institutions with lower medical resources. Extensive experiments demonstrate that the proposed framework shows significant improvement in accuracy and specificity of colon histopathological images without reliable labeled information compared to models without unsupervised domain adaptation. Specifically, in an affiliated hospital in Fuyang City, Anhui Province, the classification accuracy of benign and malignant colon histopathological images reaches 96.21%. The results of comparative experiments also show promising classification performance of our method in comparison with other unsupervised domain adaptation methods.
Designing a territorialized work system as the making of a milieu
Authors: Robert Jeanne-Martine , Béguin Pascal
Published: November 2023

BACKGROUND: A huge amount of ergonomic research has been carried out in companies. However, territory is now becoming a new frontier for decision-making during design. OBJECTIVE: This article aims to examine how territorial scale impacts the design process of a work system. METHODS: Two types of methods were used. First, we analyzed and defined what constitutes a territorialized work system. On this basis we conducted a design project for the re-conception of a territorialized work system with the linden tree. RESULTS: It is argued that a “territorialized work system” is not limited to its productive dimensions; it engages in a “making of a milieu” which consists of matching the work system with a range of dimensions that make life possible within the territory. CONCLUSION: The territorial aspect of running a design project thus relates to three dimensions: the systemic dimension of the system to be designed, the organization of the design project itself, and the nature of the object to be designed: the possibility of making a milieu, i.e. of being able to live in the territory.
Contribution Of Islamic Law To Legal Development In Indonesia
Authors: Damayanti Aula
Published: November 2023

Sistem hukum yang dipergunakan di Indonesia adalah sistem hukum civil law, yaitu sistem hukum kodifikasi atau tertulis. Kontribusi hukum islam di indonesia dilakukan pembangunan, pembinaan dan penerapan hukum Islam sebagai hukum positip dalam rangka usaha pembangunan dan pembinaan hukum nasional. Peranan Hukum Islam dalam Pembangunan Hukum di Indonesia adanya watak dinamis hukum Islam harus dikembangkan untuk menunjang perkembangan hukum nasional di alam pembangunan hukum di Indonesia ini. perlu memberikan batasan atas ruang lingkup daerah kehidupan yang dijangkau oleh hukum Islam dalam rangka pembinaan hukum nasional. Pembatasan bidang penggarapan hukum Islam ini harus ditindak lanjuti oleh para ahli hukum Islam. Penggarapan hukum Islam ini dilakukan dengan upaya merumuskan prinsip-prinsip pengambilan keputusan hukum Islam yang lebih mencerminkan kebutuhan masa kini disertai dengan perimbangan-pertimbangan kemanusiaan secara proporsional. Pada masa kemerdekaan Indonesia, hukum Islam, hukum Barat dan hukum adat sama-sama menjadi bahan bagi pembangunan unifikasi hukum nasional.
Professional ethics of judges in court
Authors: Fahira Meida Anggi , Fahmi Syawaludin Nur A.
Published: November 2023

The discourse of thought departs from the reality of law enforcers (especially judges) who ignore moral values. Even though professional actors (judges) already have a professional code of ethics as a moral standard, it has not had a positive impact, especially not being able to change society's negative image of faces. One way to uphold the rule of law is by maintaining ethics, professionalism, and discipline. The code of ethics for the profession of judges in principle contains moral values that underlie professional personality, namely freedom, justice, and honesty.
Imbalance of Rights and Obligations of Husband and Wife in the Family
Authors: Apriana Dian , Silvia Nanda
Published: November 2023

Marriage is a worship and complement of religion, marriage is also one of the scopes of discussions on Family Law. Marriage is the sunnah of the Prophet SAW. Marriage is a human right given by Allah SWT. To create a family that is sakinah mawadah, warohmah besides that the purpose of marriage is to continue the offspring, and to carry out its biological integrity. In the Department of Family Law, marriage is discussed in detail in order to create a marriage according to the Shari'a of Allah SWT. This article is entitled The Need for Rights and Obligations of Husband and Wife in the Family. This paper aims to find out what are the rights and obligations of a husband and wife in a household. In writing it uses research methods by collecting data from journals related to this discussion.
Family Achievements That Are Sakinah, Mawaddah, Warahmah
Authors: Sukmawati Berlia , Khadafi Mu’ammar
Published: November 2023

There are many things about the sakinah, mawaddah, and warohmah families, but how do people recognize and apply these concepts, namely to the sakinah, mawaddah, and warohmah families that many married couples dream of the purpose of this research is to use qualitative research methods to find out the application of the sakinah mawaddah warahmah family concept and what factors influence the creation of a sakinah mawaddah warahmah family. This research uses a type of qualitative research, and the type of research is descriptive research. The results of the study show that the sakinah mawaddah warahmah family is formed on the basis of mutual understanding between men and women in marital relations, multiplying offspring, and developing human life on the ground of love and compassion. This will create peace, peace between the two. Basically, according to the Islamic view, the factor that aims to achieve a good family life is to create a peaceful and peaceful family environment.
Online Implementation of Marriage Management Information System (SIMKAH) to Improve Service Quality
Authors: Aditya Aditya , Adi Wardana Wahyu Satya
Published: November 2023

This Scientific Writing contains the application of an online Marriage Management Information System (SIMKAH) to improve service quality. The research method used in this paper is normative legal research, which uses secondary or library data. The results of this study indicate that the application of a web-based online Marriage Management Information System (SIMKAH) at KUA is a form of modernizing marriage registration which is usually done manually in the KUA sub-district in serving the community. However, it is still not optimal because servers and networks often experience interruptions, which affect application speed. The implementation of the urgency system is an effort to support the implementation of government programs in maximizing IT-based services to the community and assisting KUA officers in the fields of marriage registration, marriage registration, marriage examinations, same marriages, and reconciliation. The quality of the information generated from the system is relevant to the needs and the output is complete and can be directly felt by users of the system and the community as recipients of the information, in this case, the procedure for recording which is usually done in writing by the administrator, can be typed into the SIMKAH program and operated by the administrator. itself so that the shape of the NB, N, and NA models can be printed/printed, and is more effective than writing. However, not all KUA apply SIMKAH optimally. As for the application of SIMKAH, it has followed the Instructions of the Director General of Islamic Community Guidance Number DJ.II/369 of 2013 concerning implementing the Marriage Management Information System (SIMKAH) at the Sub-District KUA.