bluuebunny/crossref_metadata_2025 huggingface dataset:
Multi-scale and multi-modal imaging study of mantle xenoliths and petrological implications
Authors: Venier Marco , Ziberna Luca , Mancini Lucia , Kao Alexander P. , Bernardini Federico , Roncoroni Giacomo , Milani Sula , Youbi Nasrrddine , Majigsuren Yondon , De Min Angelo , Lenaz Davide
Published: July 2023

The accurate textural characterization of mantle xenoliths is one of the fundamental steps to understanding the main processes occurring in the upper mantle, such as sub-solidus recrystallization, magmatic crystallization, and metasomatism. Texture, composition, and mineralogy reflect the temperature, pressure, stress conditions, melting, and/or contamination events undergone before and during the entrapment in the host magma. For these reasons, characterizing the three-dimensional (3D) texture of silicate, oxide, sulfide, and glass phases has great importance in the study of mantle xenoliths. We performed a multi-scale and multi-modal 3D textural analysis based on X-ray computed microtomography (µ-CT) data of three mantle xenoliths from different geodynamic settings (i.e., mobile belt zone, pericraton, oceanic hotspot). The samples were selected to represent different, variably complex internal structures composed of grains of different phases, fractures, voids, and fluid inclusions of different sizes. We used an approach structured in increasing steps of spatial and contrast resolution, starting with in-house X-ray µ-CT imaging (spatial resolution from 30 µm down to 6.25 µm) and moving to high-resolution synchrotron X-ray µ-CT at the micrometer scale.

We performed a 3D characterization of mantle xenoliths, comparing the results with the analysis of conventional 2D images (thin sections) obtained by optical microscopy and simulating the random sectioning of several thin sections to estimate the probability of correct modal classification. The 3D models allow the extraction of textural information that cannot be quantified solely from thin sections: spinel layering, distribution of silicic glass, and related vesicles. Moreover, high-density volumes identified as sulfides were detected in two xenoliths, showing no relation with the spinel layering in one case and a preferential concentration along fractures in the other. Given the variety of textures and mineral assemblages of mantle xenoliths worldwide, the results are used to suggest experimental and analytical protocols for the characterization of these materials.
Three-dimensional sculpting of laser beams
Authors: Kree Tobias , Köhl Michael
Published: July 2023

We demonstrate three-dimensional sculpting of laser beams using two-dimensional holograms. Without relying on initial guesses of the analytic properties or the Fourier transform of the desired light field, we show that an improved numerical phase retrieval algorithm can produce continuous three-dimensional intensity distributions of arbitrary shapes. We benchmark our algorithm against optical bottle beams and double-helix beams and then show the extension to complex optical structures.
A Study on Cultural Contents of National Intangible Cultural Heritage tea manufacturing(Jeda, 製茶)
Authors:   Association for International Tea Culture, Yun Byung Hwa
Published: July 2023

Jeda(製茶) is a rational process for prolonged preservation by maximizing active ingredients of tea. The government designated Jeda(製茶) as the national intangible cultural heritage as of July 14th in 2016. This study suggests the enforcement measures of Jeda transmission. First, it is support measures through legislation on tea. Active support is necessary for Jeda masters designated by Ministry of Agriculture, Food and Rural Affairs as well as providing tea manufacturing transmission system based on 「Cultural Heritage Protection Act」, 「Act on the Preservation and Promotion of Intangible Cultural Properties」, 「Act on Tea Industry Development and Tea Culture Promotion」. Second, recreational·eduational·academic·regional·economic activities are necessary to reinforce the value of Jeda. Third, it is necessary to construct a transmission institution, reinforce the support of government and local government and provide outreach educational programs for Jeda activation as national intangible cultural heritage. Fourth, Jeda should be established based on a local culture. It is necessary to work on archiving, reinforce community self-sustaining power of intangible culture and establish recreational foundation for local residents. Furthermore, it takes comprehensive effort to enhance the efficiency of Jeda cultural contents, have a multiple complex function and develop creative cultural contents.
Homology Modeling of Alpha-Glucosidase from Candida albicans: Sequence Analysis and Structural Validation Studies in silico
Authors: Ur Rashid Haroon , Bolzani Vanderlan , Khan Khalid , Dutra Luiz Antonio , Ahmad Nasir , Wadood Abdul
Published: July 2023

The alpha-glucosidase enzyme of Candida albicans plays a vital role in the pathogenesis of candidiasis, a serious fatal disease in immune-compromised patients. The unavailability of the threedimensional crystallographic structure of this enzyme creates a hindrance in developing novel and potent inhibitors. Here, an attempt has been made to design a stable three-dimensional conformer of alpha-glucosidase through in silico analysis which may be helpful for the designing of effective drugs. For this purpose, the oligo-1-6-glucosidase enzyme is used as a template for homology modeling of the alpha-glucosidase structure by Molecular Operating Environment 2011-12 software. The generated model was validated through ERRAT and Ramachandran tools, whereas its stability was studied through the molecular dynamics simulation technique. The obtained results indicate that model of alpha-glucosidase has stable secondary and tertiary arrangements. This finding may spur new directions for the rational designing and development of new antifungal inhibitors. Nevertheless, additional experimental investigations and validation are needed to confirm the in silico results of this study.
Elektrolif Çekim Yönteminde Gerilim Miktarının Poliakrilonitril Nanoliflerinin Morfolojisine Etkisi
Authors: ŞİMŞEK GÜNDÜZ Gonca
Published: July 2023

Çalışmada elektro lif çekim yönteminde farklı gerilim miktarlarında üretilen poliakrilonitril (PAN) nanoliflerinin morfolojik özelikleri incelenmiştir. Bu amaçla 14 kV, 20 kV ve 26 kV değerlerinde gerilim uygulanarak üretim yapılmıştır. Nanoliflerin çapları taramalı elektron mikroskobu (SEM) ile ölçülmüş, elde edilen çap değerlerinin istatistiki olarak karşılaştırılmasında SPSS programından yararlanılmıştır. 14 kV’ta üretilen nanoliflerin ortalama çapları 519-582 nm arasında değişirken bu değer 20kV’ta 511-566 nm ve 26 kV’ta 506-569 nm aralığında değişmiştir. Gerilim miktarı belli bir değere kadar arttırıldığında hem daha ince lifler elde edilmiş hem daha kolay çap kontrolü sağlanabilmiştir. Gerilim miktarının daha da artırılması ile boncuk oluşumunun ve boncuk büyüklüğünün arttığı görülmüştür. Ayrıca uygulanan gerilimin lif dizilimi ve lifler arası boşluğu etkilediği gözlenmiştir.
Efficient removal of perfluorinated compounds with the polyamide nanofiltration membrane and membrane fouling resistance analysis
Authors: Wu Yuyang
Published: July 2023

Perfluorinated compounds (PFCs) are significant pollutants known for their high toxicity and resistance to natural degradation, posing a severe threat to both the global environment and human health. In this study, a polyamide (PA) membrane with an intermediate layer structure of MXene-TiO2 (referred to as MXT-NFM) was utilized for the removal of PFCs. Experimental results confirm that MXT-NFM exhibited remarkable capacity in intercepting PFCs, accompanied by the high water flux. To gain insights into the mechanisms governing membrane fouling induced by PFCs, inorganic ions, and organics, a series of fouling tests were conducted using MXT-NFM under diverse conditions. Additionally, the XDLVO theory was employed to provide a theoretical perspective on the interactions occurring during the fouling process. The findings suggest that the MXene-TiO2 intermediate layer contributed to the exceptional hydrophilicity and rough surface properties, enabling multiple functionalities. These include alleviating membrane pore plugging, improving the physical configuration of the PA layer, and effectively mitigating fouling phenomena in coexisting systems during practical applications. Moreover, the particle size of pollutant colloids and the acid–base interaction were identified as decisive factors influencing the development of membrane fouling.
Molecular Mechanisms and Therapeutic Potential of Resolvins in
Cancer - Current Status and Perspectives
Authors: Tajbakhsh Amir , Yousefi Fatemeh , Farahani Najmeh , Savardashtaki Amir , Reiner Željko , Jamialahmadi Tannaz , Sahebkar Amirhossein
Published: July 2023

:

Resolvins are specialized pro-resolving mediators derived from omega-3 fatty
acids that can suppress several cancer-related molecular pathways, including important
activation of transcription parameters in the tumor cells and their microenvironment, inflammatory
cell infiltration, cytokines as well as chemokines. Recently, an association between
resolvins and an important anti-inflammatory process in apoptotic tumor cell clearance
(efferocytosis) was shown. The inflammation status or the oncogene activation increases
the risk of cancer development via triggering the transcriptional agents, including
nuclear factor kappa-light-chain-enhancer of activated B cells by generating the pro-inflammatory
lipid molecules and infiltrating the tumor cells along with the high level of
pro-inflammatory signaling. These events can cause an inflammatory microenvironment.
Resolvins might decrease the leukocyte influx into the inflamed tissues. It is widely accepted
that resolvins prohibit the development of debris-triggered cancer via increasing
the clearance of debris, especially by macrophage phagocytosis in tumors without any
side effects. Resolvins D2, D1, and E1 might suppress tumor-growing inflammation by
activation of macrophages clearance of cell debris in the tumor. Resolvin D5 can assist
patients with pain during treatment. However, the effects of resolvins as anti-inflammatory
mediators in cancers are not completely explained. Thus, based on the most recent
studies, we tried to summarize the most recent knowledge on resolvins in cancers.
An Insight on Skin Cancer About Different Targets With Update on
Clinical Trials and Investigational Drugs
Authors: Vishwas Suraj , Das Paul Swarnali , Singh Deepika
Published: July 2023

Cancer is a diverse disease caused by transcriptional changes involving genetic and epigenetic
features that influence a huge variety of genes and proteins. Skin cancer is a potentially fatal disease
that affects equally men and women globally and is characterized by many molecular changes. Despite
the availability of various improved approaches for detecting and treating skin cancer, it continues to be
the leading cause of death throughout society. This review highlights a general overview of skin cancer,
with an emphasis on epidemiology, types, risk factors, pathological and targeted facets, biomarkers and
molecular markers, immunotherapy, and clinical updates of investigational drugs associated with skin
cancer.

:

The skin cancer challenges are acknowledged throughout this study, and the potential application of
novel biomarkers of skin cancer formation, progression, metastasis, and prognosis is explored. Although
the mechanism of skin carcinogenesis is currently poorly understood, multiple articles have
shown that genetic and molecular changes are involved. Furthermore, several skin cancer risk factors
are now recognized, allowing for efficient skin cancer prevention. There have been considerable improvements
in the field of targeted treatment, and future research into additional targets will expand
patients’ therapeutic choices. In comparison to earlier articles on the same issue, this review focused on
molecular and genetic factors and examined various skin cancer-related factors in depth.
Self-assembling Peptides (SAPs) as Powerful Tools for the Preparation of Antimicrobial and Wound-Healing Nanostructures
Authors: Dimmito Marilisa Pia , Marinelli Lisa , Cacciatore Ivana , Valeri Anna Lucia , Rapino Alessandra , Di Stefano Antonio
Published: July 2023

:

Supramolecular self-assembly (SA) is a naturally occurring and free energy-driven process of molecules to produce nanostructured systems depending on the assembling environment. SA molecules have captivated the research attention since they possess singular physicochemical properties that are potentially useful to make the nanostructures quite suitable for biomedical applications, such as diagnostics, drug delivery, tissue engineering, and regenerative medicine. Due to their high biological activity and low toxicity, the self-assembly properties of peptides bid certain advantages as drugs and drug delivery platforms. Among the discovered self-assembling bioactive peptides (SAPs), antimicrobial peptides (AMPs) are widely distributed through plant and animal kingdoms and play a key role as an alternative strategy to fight infections bypassing conventional antimicrobial drugs, susceptible to antimicrobial resistance. Based on this evidence, in this review, we summarized the mechanism of the self-assembling of peptides, the main forces responsible for the SAPs formation, and the studies regarding their possible implication in infectious diseases as well as wound dressing materials.
1,3,4-Oxadiazoles as Anticancer Agents: A Review
Authors: Kumar Greesh , Kumar Rajnish , Mazumder Avijit , Salahuddin  , Kumar Upendra
Published: July 2023

Among the deadliest diseases, cancer is characterized by tumors or an increased number
of a specific type of cell because of uncontrolled divisions during mitosis. Researchers in the
current era concentrated on the development of highly selective anticancer medications due to the
substantial toxicities of conventional cytotoxic drugs. Several marketed drug molecules have provided
resistance against cancer through interaction with certain targets/growth factors/enzymes,
such as Telomerase, Histone Deacetylase (HDAC), Methionine Aminopeptidase (MetAP II),
Thymidylate Synthase (TS), Glycogen Synthase Kinase-3 (GSK), Epidermal Growth Factor
(EGF), Vascular Endothelial Growth Factor (VEGF), Focal Adhesion Kinase (FAK), STAT3,
Thymidine phosphorylase, and Alkaline phosphatase. The molecular structure of these drug molecules
contains various heterocyclic moieties that act as pharmacophores. Recently, 1,3,4-
oxadiazole (five-membered heterocyclic moiety) and its derivatives attracted researchers as these
have been reported with a wide range of pharmacological activities, including anti-cancer. 1,3,4-
oxadiazoles have exhibited anti-cancer potential via acting on any of the above targets. The presented
study highlights the synthesis of anti-cancer 1,3,4-oxadiazoles, their mechanism of interactions
with targets, along with structure-activity relationship concerning anti-cancer potential.
Pulsatilla saponin A Inhibits Proliferation and Induces Apoptosis in Diffuse Large Bcell
Lymphoma Cells through the JAK2/STAT3 Signaling Pathway
Authors: Liu Ning , Zhan Xinzhuo , Bai Jie , Yu Hui , Chen Xiaoli , Kong Xiangtu , Ni Haiwen
Published: July 2023

Objective:

This study aimed to investigate the performance of Pulsatilla saponin A (PsA) in diffuse large
B-cell lymphoma (DLBCL) cells.

Methods:

Proliferation, ELISA, apoptosis, cell cycle analysis, and assays were carried out to detect the growth and
apoptosis in DLBCL cells. Western blotting was used to identify the change in the protein.

Results:

In cell assays, PsA significantly inhibited the growth and apoptosis in DLBCL cells. The IL-10 and TNF-α of
OCI-LY10 and U2932 cells were reduced after 24 h PsA treatment. Bax, cleaved PARP, and cleaved Caspase-3 were
increased, while Bcl-2 and C-Myc decreased after PsA treatment. IL-10 may regulate the expression of C-Myc protein
in cells by activating the JAK2/STAT3 signaling pathway. PsA can inhibit the overexpression of p-JAK2 and p-
STAT3 signaling pathways induced by IL-10 stimulants. The proliferation and apoptosis induced by PsA were confirmed
in DLBCL cells.

Conclusion:

Our findings revealed that PsA may exert its antitumor effect by causing G1 arrest and apoptosis in
DLBCL cells. The mechanism of PsA regulating apoptosis in DLBCL cells is probably through the JAK2/STAT3
signaling pathway in vitro.
Analysis of MMSE Multiuser Detector in a Low-density Parity Check
Coded Large Scale MIMO OFDM
Authors: Shoukath Shefin , Haris P. Abdul
Published: July 2023

Background:

Large-scale MIMO OFDM technique satisfies the demands on performance
and the service quality preferred in wireless communication systems. Since numerous antenna terminals
have been incorporated in the base station, multiuser detection is crucial for retrieving the data
appropriately. Thus, the complexities of the detectors increase rapidly in large-scale MIMO OFDM
schemes.

Objective:

This work is a solution to achieve an extensively high rate of data transmission, which will
help improve the capacity of the LS MIMO OFDM system.

Methods:

A unique detection approach of multiuser detection in LS MIMO OFDM model with channel
coding, like Low Density Parity Check Codes (LDPC), is suggested in this paper. The LDPCcoded
large-scale MIMO OFDM system has also been analysed in the study with users of around ten
at the transmitter and several antennas in the base station.

Results:

BER of the LDPC-coded LS MIMO OFDM exhibited a waterfall region for SNR greater
than 6dB as the study has been done with different decoding iterations. The BER performance
worsened with the increase in modulation symbols. The study has shown how the BER performance
has improved with respect to the increasing fading channels and subcarriers.

Conclusion:

The proposed system exhibited performance closer to the MIMO capacity with low
complexity MMSE detection. The multiuser detector of LDPC-coded LS MIMO OFDM has been
analysed by error rate in received bits (BER) with respect to different parameters, such as modulation
orders, iteration values, receiving antennas, and OFDM subcarriers.
A Review on Anti-leishmanial Activity of Terpenes and Chitosan as a Carrier for Nano-formulations
Authors: Goel Tanvi , Bansode Deepali
Published: July 2023

Leishmaniasis is one of the most devastating and fatal diseases in humans that has been
known to mankind and is caused by the parasite Leishmania. It is destructive since no vaccination is
available and existing medicines are proving ineffective because of resistance development.

:

A need for the discovery of newer drugs has emerged. The use of natural products for the prevention,
diagnosis, and cure of diseases has rapidly increased. Following the trend, research in the field
of natural products for treating leishmaniasis has also picked up. In the present review, the focus is
on terpenes as anti-leishmanial agents. Terpenes are the least studied natural products for the treatment
of the disease. The other part of the review covers the use of chitosan as an anti-leishmanial
agent and other formulations of chitosan as a carrier in nano-formulations.

:

From the survey, it was found that the essential oils containing terpenes are very effective. Moreover,
the chitosan-based nanocarriers showed potent anti-leishmanial activity. The combined use of
natural products and newer technologies for the delivery of drugs can eradicate various diseases.
Multienzyme Complex in Fatty Acid Biosynthesis
Authors: Prabhakaran Pranesha , Nazir Yusuf , Halim Hafiy , Abdul Hamid Aidil , Song Yuanda
Published: July 2023

Fatty acid biosynthesis is a fundamental process that occurs in all living
organisms and involves multiple reaction steps. Thus, a systematic transfer of the
intermediates between the different catalytic sites is highly required for the efficient
regulation of a pathway as well as for sustaining growth. Multienzyme complex, a
protein complex that comprises a group of interacting enzymes in a specific metabolic
pathway, has been identified to catalyze numerous metabolic pathways, including fatty
acid synthesis. The existence of a lipogenic multienzyme complex that involves protein
interaction between numerous enzymes that took part in fatty acid biosynthesis plays a
key fundamental role in channelling the intermediate substrates. Herein, the growing
evidence for the formation of multienzyme complexes in fatty acid synthesis and the
properties of the complex will be elucidated in this chapter.
THE SURGEON'S PERSPECTIVE ON PORTAL VEIN THROMBOSIS IN PATIENTS WITH LIVER CIRRHOSIS
Authors: Vasyliuk S.M. , Hudyvok V.I. , Labiak І.R. , Pavliuk N.M. , Atamaniuk V.M.
Published: July 2023

The article discusses the key aspects of the etiology, diagnosis, and treatment of portal vein thrombosis in patients with liver cirrhosis. The prevalence of portal vein thrombosis in individuals with liver cirrhosis ranges from 0.6 % to 26 %, with a higher incidence observed in those with decompensated cirrhosis. Symptoms of portal vein thrombosis are often nonspecific. Approximately one-third of patients with this condition experience no symptoms, and the detection of a thrombus is usually an incidental finding during computed tomography or ultrasound examinations.
Acute portal vein thrombosis is characterized by abdominal pain in the right upper quadrant, non-bloody diarrhea, or acute intestinal obstruction when there is symptomatic dilatation of the superior mesenteric vein. On the other hand, chronic portal vein thrombosis manifests through signs of portal hypertension, such as esophageal and gastric bleeding, deterioration of portal gastropathy, splenomegaly, pancytopenia, and significant ascites.
The first-line treatment for portal vein thrombosis involves the use of direct and indirect anticoagulants. However, their administration necessitates careful consideration of the risk of intraluminal bleeding, the severity of cirrhosis, and the potential benefits of portal vein recanalization. Mechanical thrombectomy can serve as an alternative to long-term anticoagulant therapy for portal vein thrombosis. In cases of portal vein thrombosis in patients with cirrhosis, after mechanical thrombectomy and thrombolysis, the placement of transjugular intrahepatic portosystemic shunt (TIPS) is often performed.
To conclude, portal vein thrombosis frequently occurs in patients with liver cirrhosis, and its appearance is challenging to predict due to its multifactorial nature. The preferred initial treatment for acute portal vein thrombosis, in the absence of intraluminal bleeding or intestinal ischemia, involves the use of direct and indirect anticoagulants. Minimally invasive surgical options, such as mechanical thrombectomy, chemical thrombolysis, and TIPS placement (with or without variceal embolization), are currently available. However, due to the heterogeneous nature of the existing data and the lack of randomized controlled trials, definitive recommendations regarding the optimal treatment strategy are not yet available.
Keywords: cirrhosis, coagulopathy, portal hypertension, portal vein thrombosis, anticoagulants.
The Future of Work and Teleworking: A Conceptual Study of Employee Preferences, Managerial Strategies, and RTO Mandates
Authors: Jacques Paul H. , Garger John , Mullen Angela , Petrarca Pietro
Published: July 2023

This conceptual paper examines how personality, mediated by cognitive processes as described by Ajzen’s (1991) Theory of Planned Behavior (TPB), influences employees’ attitudes toward tele-working. Research suggests that superior outcomes and attitudes associate with teleworking, but such research is one-dimensional because nomological relationships that associate attitudes and teleworking do not include cognitive components that research has long demonstrated predict atti-tudes. The current study constructs a richer, more predictive model that uses the TPB to explore, in greater depth, how employees’ attitudes associate with teleworking from home versus working in an office. The study uses a five-factor model to assess how individuals view teleworking based on traits that best classify personalities, offering managers greater understanding of the forces that shape employees’ work preferences.
The CEO as Monopolist
Authors: Mulligan Robert F.
Published: July 2023

CEOs can extract extraordinarily high income from the firms they manage because of their monopoly power. This derives both from a general preference for hiring proven CEOs who have already served at other firms, as well as from the tendency of new CEOs to reorganize the firms they lead. Firms’ status quo bias unnaturally delimits the pool of CEO applicants and increases the monopoly power of incumbent CEOs. New CEOs who install their own top management teams generally reorganize the firm to optimize the application of their own abilities and those of their new team. However, CEOs can also reorganize to maximize their monopoly power. Conceptualizing CEOs as potential monopolists integrates insights from the principal/agent, upper echelon, efficiency wage, and x-inefficiency literatures. This paper develops the consequences of monopolistic CEOs who potentially receive efficiency wages that may exceed their marginal revenue product. If CEO income is sufficiently high, their labor-supply curves bend backwards, something far less likely for other employees. A backward-bending labor-supply curve can result in CEOs receiving even greater income as they deliver even lower levels of executive leadership.
Students’ Mental Models For Molecule Shapes Concepts: A Multiple-Repesentation Perspective
Authors: Siregar Erlina Azmi , Wiyarsi Antuni
Published: July 2023

This research aims to explores the mental model of high school students on the concept of molecular shape from the aspects multiple representation. This research used explorative survey with qualitative approach involving 20 participants selected using the purposive sampling. The data analysis carried out in this study was iterative content analysis to determine a consistent pattern in the participants' answers. The results of this study are as follows there are 33% of students with the target mental model (MMT) category from the symbolic representation aspect on the concept of writing electronic configurations, writing Lewis structures and determining the number of PEB and PEI, 5% of students with the target mental model (MMT) category from the submicroscopic representation aspect on the concept of VSPER theory while on the concept of compound polarity from the macroscopic representation aspect, 35% of students. This is due to the large number of students who have mixed mental model (MMC) and alternative mental model (MMA) categories. In addition, there were 2 students who had an unexplored mental model (MMTT). The low mental model of students is due to the low understanding of students towards multiple representation on the concept of molecular shapes.
Implementation of Teledermatology for Veterans in the United States
Authors: Oh Dennis
Published: July 2023

Conflicts of Interest

None declared.
A Survey on the Application of Game Teaching Method in English Teaching of Primary School: A Case Study of a Primary School in Our Local City
Authors: Ruisi Wang
Published: July 2023

The game based teaching method is specifically aimed at assisting English teaching, communicating in English, and widely used in English classrooms or extracurricular activities. Compared with Chinese, primary school students lack a certain language environment for English learning and do not have a true understanding of English learning. Therefore, English teachers should use games to mobilize students’ enthusiasm for learning, and follow the basic principle of “happy teaching” to adapt to students’ development. However, there are still many problems with game teaching methods in English teaching. This thesis wants to explore the current situation of the application of games in English teaching and research its countermeasures, so that more front-line teachers can benefit from it.This study is based on Piaget’s cognitive development theory and happiness education theory. By using the methods of questionnaire survey and interview, this paper delves into the current application status, existing problems, and cause analysis of game teaching methods in primary school English classrooms. And the study summarized the shortcomings of current primary school English teachers in the application of classroom game teaching methods.It is found that the main problems are: in ordinary classes, the use of game-based teaching methods is still relatively limited; students’ game goals are unclear and cannot be applied to practice; the class is chaotic; and all students cannot participate in the game.The study suggests that the teacher enrich the theoretical knowledge of game teaching methods and strengthen their application. Schools can provide training for teachers at appropriate times, or regularly order publications or books related to games. Teachers can also learn more from successful game application cases to improve the application ability of game teaching methods. For the student group, research suggests that students clarify the purpose of games and enable them to understand the true intention of the teacher in using games in the classroom. Secondly, it is necessary to strengthen students’ classroom discipline.Through in-depth exploration of the practice of game teaching methods in primary school English classrooms, it has reference value for primary school English teachers to correctly and effectively implement game teaching methods, and has profound significance for better implementing game teaching methods in primary school English classrooms.
Incorporating Complexity Theory in Collaborative Educational Programs
Authors:   Sacred Heart University, Chen Ximeng
Published: July 2023

The field of education has witnessed an increasing trend of inter-organizational and inter-departmental collaborations and forming of networks. Collaborative educational programs have been implemented in a variety of ways. This paper proposes to understand and study collaborative educational programs through the lens of complexity theory and to utilize nonlinear research methods. This paper also proposes to connect the dots in the literature among complexity theory, collaborative educational programs, program evaluation, and alternative nonlinear research methods.
Experimental Study on Compressive Strength of Magnesium Oxychloride Cement Mortar Using Stone Crushed Powder by Varying Molar Ratio
Authors: Marupakula Pavan Kumar , Rachamalla Sai Kiran
Published: July 2023

Abstract: One of the major consumers of natural resources and a significant contributor to CO2 emissions is the construction sector. The manufacture of cement and building materials was found to be the source of the highest greenhouse gas emissions. In order to lessen the damaging effects of the building industry on the environment, this paper seeks to determine whether magnesium oxychloride cement (MOC) may be used as a mortar substitute for regular Portland cement. A thorough review of the literature, an experimental investigation, and an internal structure analysis based on the ideal molar ratio are all part of the research technique. In this study, MOC cement with powdered stone is experimentally investigated utilizing various molar ratios with phases 3 and 5. In the first set of results usage of unheated magnesium oxide powder, SEM image shown some amount of MgO left inactive and compressive strength depicted lower values. Eventually, a modification was implemented in order to boost compressive strength. In order to improve the reaction or gel formation that would boost the compressive strength, the MgO powder was heated and added to the cement. Different molar ratios produced various compressive strength values in the mortar cubes. Two ideal molar ratios are chosen from each phase, SEM and EDXA are used to analyse the micro structure. The MgO6 octahedral crystal structures of Phases 3 and 5 are visible in the SEM pictures as double and tripple ribbons of shared edges with water molecules and chloride anions. The percentage of elemental weight in the specimens is displayed by EDXA.
Pelatihan Penerapan Wafer Pakan Untuk Meningkatkan Produktivitas Kambing Pada Pondok Pesantren Madinatul Ilmi Di Gresik
Authors: Retnani Yuli , Rahayu Iman , Risyahadi Sazli Tutur , Taryati
Published: July 2023

Madinatul Ilmi Surowati Islamic Boarding School has mission to make its students successful preachers who have livestock businesses. Santri were also given facilities for raising goats and cows and were sent to school at SMK Muhammadiyah 5 Gresik in the Ruminant Livestock Department. However, the feed used tends to be expensive to achieve the desired quality and has not optimized local sources of feed ingredients. This can be caused by knowledge of feed raw materials and feed processing processes that are deemed inadequate to make feed. For this reason, the IPB lecturer team held community service with training methods on feed insights and innovative feeding practices, namely feed wafers. Evaluation is done by asking questions before and after the training so that the indicators of success are more measurable. The results show that there is an increase in the number of students who understand forage feed and feed wafers. After the training, the number of students who already understand the technique of giving feed wafers increased from only 5% before the training to 60%. After training. In addition, it is shown by the number of participants being motivated to explore various local feed ingredients to be used as ruminant feed.
PELATIHAN DIGITAL MARKETING BAGI WIRAUSAHA BARU KOTA CIMAHI BANDUNG
Authors: Afifah  , Fitri Adona  , Ruzita Sumiati  , Yuhefizar
Published: July 2023

Pemasaran digital merupakan metode pemasaran produk atau jasa menggunakan teknologi informasi. Metode ini diyakini dapat memperluas pangsa pasar, meningkatkan awareness dan meningkatkan penjualan. Oleh sebab itu pemahaman dan keterampilan memasarkan secara digital dilatihkan pada 20 (dua puluh) Usaha Mikro Kecil Menengah (UMKM) yang tergabung dalam Wirausaha Baru Kota Cimahi. Pelatihan ini diberikan dengan metode tatap muka dan online. Pelatihan tatap muka dilaksanakan di Cimahi Techopark sedangkan pelatihan online melalui aplikasi zoom. Materi pelatihan yang bersifat teori meliputi: pemahaman tentang pemasaran konvensional dan digital; teknik bahasa iklan yang menarik. Materi lain yang diberikan adalah keterampilan memanfaatkan media social dan website sebagai media pemasaran digital, materi ini bersifat praktek. Dari kegiatan pelatihan yang dilakukan, peserta sudah dapat pemahaman pentingnya pemasaran digital bagi peningkatan kinerja usaha mereka dan peserta juga sudah mengetahui bagaimana membuat iklan dengan bahasa yang tepat dan menarik. Hasil lainnya adalah peserta sudah mengetahui bagaimana memanfaatkan social media sebagai sarana media pemasaran digital dan salah satu peserta dibuatkan website percontohan.
Surgical outcome of “Neurogenic claudication and walking limitation” due to degenerative Lumbar spinal canal stenosis
Authors: Rasheed Handern M. , Ali Amanj H. , Mohammed Nashaddin A.
Published: July 2023

Objectives: This study aimed to evaluate the efficacy of surgical decompression of the lumbar spinal canal, a procedure involving the removal of ligamentum and other degenerated elements causing pressure on the thecal sac, nerve roots, and neurovascular structures. The procedure is considered essential for patients experiencing neurogenic claudication, low back pain, lower limb pain and paresthesia, and decreased walking performance, to effectively decompress the lumbar canal.

Methods: A retrospective analysis was conducted on patients who underwent surgical decompression at Shar hospital between 2018 and 2020. A total of 57 eligible patients were followed up to assess the outcomes related to neurogenic claudication and walking ability after 12-24 months postoperatively.

Results: The postoperative results for neurogenic claudication and walking ability were found to be satisfactory in nearly three-quarters of the cases. The duration of symptoms significantly influenced the results, while factors such as gender, body mass index, smoking history, the number of stenosed levels operated, and the type of stenosis did not show significant impact.

Conclusion: Surgical decompression for degenerative lumbar canal stenosis is a relatively low-risk procedure with a very high rate of postoperative patient satisfaction regarding neurogenic claudication and improved walking distance. These positive outcomes are particularly evident when the procedure is performed promptly, by an experienced surgeon, and with appropriate patient selection.
II Colóquio de Gênero e Literatura na Amazônia: reafirmando e construindo saberes plurais e epistemologias decoloniais
Authors: de Barros Ataide Luciana , Ferreira Santos Edimara , Negreiros Alves Alice Margarida
Published: July 2023

Este livro apresenta artigos de pesquisadoras/pesquisadores de várias instituições nacionais e internacionais que apresentaram as suas pesquisas na segunda edição do Colóquio "Gênero e Literatura na Amazônia: Reafirmando Saberes Plurais e Epistemologias Decoloniais". O interesse desta edição foi discutir e pluralizar temáticas como Gênero, Feminismo e Literatura na perspectiva de materializar/concretizar os diálogos entre os saberes produzidos nas universidades e nas escolas; e os saberes dos movimentos sociais, ribeirinhos, negras/negros, periféricas/periféricos, quilombolas, indígenas e LGBTQIAP+. A intenção foi termos um espaço de diálogo com multivozes que compõem o nosso país, na construção efetiva da produção do conhecimento que visa a reforçar as lutas pelas emancipações coletivas sociais.
ATTACHING NOSE TO THE PLACE OF PROSTRATION
Authors: Binti Tajul Ashikin Nur Najihah Aula
Published: July 2023

The government has implemented health protocols to limit the spread of Covid-19, including wearing masks. However, problems arise when wearing a mask while praying. According to the Ḥanbalī school of thought, this prayer is invalid. On the other hand, according to the ulemas of the al-Syafi'ī school, prayers are still valid even if a mask is covered the nose. The author is interested in examining the opinions and methods of these two schools with a comparative legal approach. The authors found that most ulemas of Ḥanbalī schools stated that the nose is a part of the body that must be attached to the place of prostration in prayer. The ulemas of the al-Syafi'i school state that only the forehead must touch the place of prostration, while the nose is only a suggestion. The ulemas of both schools use linguistic (lughawiyyah) and causation (ta‘līl) methods, but the results are different. It happens because of differences in the editorial hadith used as a source of law. The author concludes that the ulemas of these two schools have such tendencies about different editors' hadiths choosing.
PRAYER BEHIND THE IMAM OF DIFFERENT MAZHAB
Authors: Bin Ahmad Khadri Anas Naufal
Published: July 2023

Imam al-Qaffāl (d. 417 H), who lived in the 5th century Hijriyyah, stated that prayers behind imams of different madhabs are valid because the benchmark is the legal requirements for prayers according to the imam. Whereas Ibn Ḥajar al-Haytamī (d. 974 H), who lived in the 10th century Hijriyyah, stated that it was invalid if the imam did something that caused the prayer invalid according to the makmum. The author examines these two opinions with a comparative approach from the perspective of fiqh al-ikhtilāf. The concept is the difference as diversity or difference as opposition. It has revealed that these two opinions must be moderate. On the one side, the makmum must be careful of imams who are much more proud of their personal or group opinions. On the other side, they must be kind to the imam. It has to consider that the differences cannot to eliminated, so the authors conclude that the best solution is to moderate between the imam's perspective and the makmum's. Thus, differences of opinion become a blessing for the people.
Questioning the presence of anal symptoms in patients applying to the family medicine outpatient clinic
Authors: ELAGÖZ Tuğba , ÖZBAY Fatih , COŞAR ÇOBANLAR Esra , KURAL ATAK Rukiye , VATANSEVER BALCAN Merve , ELBİ Hüseyin , OZCAN Fatih
Published: July 2023

Introduction: Patients usually hide anal region diseases due to the sensitivity of the anal area. Questioning and successfully managing anal region disease symptoms in primary care will prevent late diagnosis of underlying diseases. This study aims to investigate the presence of anal symptoms in patients admitted to family medicine outpatient clinics for any reason.

Methods: Our research is a descriptive study. A questionnaire form was created by scanning the literature, was applied by 5 different research assistants to patients aged 18 and over who applied to the family medicine outpatient clinic. It is aimed to reach the maximum number of individuals with the improbable sample.

Results: 64.8% of the 165 participants included in the study are female, and 35.2% are male, with a mean age of 35,69 ± 14,53 (Min:18, Max:75). Anal symptoms were detected in 46 patients (27.9%) after questioning. The most frequently reported symptoms were constipation with a rate of 14.5% (n=24), rectal pain at a rate of 7.9% (n=13), rectal bleeding at a rate of 7.3% (n=12), rectal swelling at a rate of 5.5% (n=9) and rectal itching at a rate of 3.6% (n=6). 81.8% of these patients reported that they could share with their doctor when they have symptoms of moderate severity and above. 86.1% (n=142) said they would accept digital rectal examinations if necessary.

Conclusion: It is crucial to determine the prevalence of anal symptoms in the general population. Although these symptoms affect the quality of life by causing severe pain and discomfort, they are rarely shared by patients. Routine questioning and examination of anal area symptoms enable more effective disease management. The majority of cases can be diagnosed after examination in primary care. Therefore, the first step is essential for the early diagnosis and treatment of these diseases.

Keywords: Rectal Disease, Family Medicine, Digital Rectal Examination
Coordenador pedagógico no processo de acompanhar, aprender e se (trans)formar junto ao aluno com deficiência
Authors: Nascimento Franc-Lane Sousa Carvalho do , Morais Joelson de Sousa , Carvalho Filha Francidalma Soares Sousa
Published: July 2023

No presente artigo pretendemos como objetivo: compreender os processos de (trans)formação do coordenador pedagógico no acompanhamento do aluno com deficiência no contexto da educação especial e inclusiva. Trata-se de um estudo com abordagem de pesquisa qualitativa, utilizando-se os métodos dedutivo-indutivo, e como instrumentos de investigação: a observação participante e o questionário semiestruturado. De acordo com os resultados, as reflexões evidenciam que os Coordenadores Pedagógicos sentem dificuldades por falta de formação continuada para eles e os professores; não sabem como desenvolver estratégias metodológicas e didáticas que ajudem na aprendizagem dos alunos; falta apoio por parte da Secretaria Municipal de Educação, família e da escola para o acompanhamento dos alunos deficientes que possa favorecer no desenvolvimento social, afetivo e cognitivo. Além disso, as reflexões do estudo demonstram que para essas profissionais, a inclusão nos contextos educacionais e formativos contribui com a inserção, permanência e desenvolvimento social e educacional das pessoas com deficiência.
processo de colaboração entre família e escola como possibilidade de formação humana de estudantes em espaço escolar
Authors: Marques Eliana Sousa Alencar , Pessoa Jean Carlos de Sousa
Published: July 2023

O presente artigo tem como objetivo discutir como se articulam as relações entre família e escola e como essas instituições podem ajudar no processo de reprodução social, a fim de colaborar com a educação para formação humana. A pesquisa, do tipo bibliográfica, é apoiada nas ideias de Lukács, sobre complexos sociais, e em pesquisas que se dedicam à problemática família e escola. A discussão reflete, de forma mais ampla, que, respeitando suas especificidades, família e escola atuam como complexos sociais responsáveis pela formação dos seres humanos e que, portanto, precisam assumir relação de colaboração quando se trata dos processos educativos escolares. Entretanto, nem sempre isso acontece. Tradicionalmente essa relação tem sido marcada por tensões e omissões. Os resultados desta pesquisa apontam que, assumindo a colaboração, família e escola dialogam e atuam conjuntamente, respeitando seus limites e possibilidades no desenvolvimento de ações que medeiam a formação humana.
Jogos digitais como objetos da comunicação
Authors: Madeira da Silva Soraya , Jorge de Lucena Lucas Ricardo
Published: July 2023

O objetivo deste trabalho é aproximar os game studies e a comunicação, a partir de reflexões sobre os jogos digitais como objetos de pesquisa, discorrendo sobre a análise de jogos e seu caráter comunicacional. Ao aproximar as duas áreas, compreendemos o jogo digital como um artefato técnico indissociável do indivíduo e também como um objeto comunicacional dotado de particularidades específicas, com impacto na cultura e na sociedade. Através de uma pesquisa bibliográfica de natureza exploratória, concluímos que videogames podem se beneficiar de sua proximidade com a comunicação para uma elaboração epistemológica, teórica e metodológica distinta, contribuindo para fortalecer as pesquisas na comunicação e nos game studies no Brasil.
Videoaulas segundo a Teoria Histórico-Cultural
Authors: Gonçalves Josiane Peres , Barbosa Leandro Piccini
Published: July 2023

A Teoria Histórico-Cultural de Vigotski apresenta diversos conceitos importantes e que contribui para a aprendizagem humana. Neste estudo bibliográfico, o objetivo é analisar e relacionar os conceitos de mediação, signo e linguagem, funções psicológicas superiores e zona de desenvolvimento proximal (ZDP) com as videoaulas, as quais podem ser utilizadas como recurso metodológico no contexto educativo. Inicialmente apresenta-se cada um dos quatro conceitos mencionados, para em seguida relacioná-los com as videoaulas. Evidencia-se que o uso das tecnologias na escola, mais especificamente das videoaulas, é entendido como formas de mediação e de linguagem diferenciada, que contribui para ampliar as funções psicológicas superiores e a ZDP dos alunos.