bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table S1 from Rapamycin Prevents Surgery-Induced Immune Dysfunction in Patients with Bladder Cancer
Authors: Svatek Robert S. , Ji Niannian , de Leon Essel , Mukherjee Neelam Z. , Kabra Aashish , Hurez Vincent , Nicolas Marlo , Michalek Joel E. , Javors Martin , Wheeler Karen , Sharp Z. Dave , Livi Carolina B. , Shu Zhen-Ju , Henkes David , Curiel Tyler J.
Published: April 2023

Complication data for all patients
Figure S3 from Immune-Checkpoint Blockade Opposes CD8+ T-cell Suppression in Human and Murine Cancer
Authors: Pfannenstiel Lukas W. , Diaz-Montero C. Marcela , Tian Ye F. , Scharpf Joseph , Ko Jennifer S. , Gastman Brian R.
Published: April 2023

Supplementary Figure 3 . CD3+ CD8+ PD-1+ Tim-3+ and CD3+ CD8+ CD27- CD28- cells were sorted from SCCHN tissue. Purified cells were then used in an in vitro suppression assays with autologous T cells. Ratios indicate the number of suppressors to responders. Controls are using equivalent numbers of responder cells alone. Responders were labeled with CFSE. BrdU was added during the final 18 hours of culture. Indicated data are representative of at least three independent experiments. Error bars represent SD of replicate wells for each condition.
Figure S2 from Immune-Checkpoint Blockade Opposes CD8+ T-cell Suppression in Human and Murine Cancer
Authors: Pfannenstiel Lukas W. , Diaz-Montero C. Marcela , Tian Ye F. , Scharpf Joseph , Ko Jennifer S. , Gastman Brian R.
Published: April 2023

Supplementary Figure 2 A. Dissociated SCCHN tumor tissue was stained for the indicated antibodies. Displayed dot plots are gated on CD3+ CD8+ T cells. Arrow indicates the CD45RA/CCR7 plots derive from the indicated CD27/CD28- or PD-1+/Tim-3+ gate. B. Staining of freshly isolated mouse splenocytes or dissociated TC-1 tumor tissue. Middle dot plots are derived from CD3+ CD8+ gates drawn on left panels. Arrows indicate the PD-1+/Tim-3+ gated population (blue) that was overlaid on total CD3+ CD8+ cells comparing CD62L/CD44 expression
Table S1, Table S2, Figure S1, Figure S2, Figure S3, Figure S4 from Wnt3a/β-Catenin Signaling Conditions Differentiation of Partially Exhausted T-effector Cells in Human Cancers
Authors: Schinzari Valeria , Timperi Eleonora , Pecora Giulia , Palmucci Francesco , Gallerano Daniela , Grimaldi Alessio , Covino Daniela Angela , Guglielmo Nicola , Melandro Fabio , Manzi Emy , Sagnotta Andrea , Lancellotti Francesco , Sacco Luca , Chirletti Piero , Grazi Gian Luca , Rossi Massimo , Barnaba Vincenzo
Published: April 2023

Table S1. Characteristics of all enrolled patients (HCC=35, CRC=16), not previous treated with chemotherapy Table S2. List of all antibodies for FC analysis Figure S1: CD4 and CD8 T cells expressed high levels of PD1 in TUM district and showed mostly an effector memory phenotype in CRC Figure S2: Distribution of Wnt3a in serum, NTUM- or TUM-derived CM, and expression of Wnt3a/β-catenin axis in NTUM and TUM-infiltrating CD4 and CD8 T cells from CRC patients Figure S3: Analysis of Frizzled receptor 1 expression among CD4 and CD8 T cells in periphery, nontumor and tumor samples of HCC patients Figure S4: β-catenin+ tumor-infiltrating CD4 T cells in presence of anti-Wnt3a do not down-regulated TNF-α prduction
Supplementary Figure Legends from Concurrent PD-1 Blockade Negates the Effects of OX40 Agonist Antibody in Combination Immunotherapy through Inducing T-cell Apoptosis
Authors: Shrimali Rajeev K. , Ahmad Shamim , Verma Vivek , Zeng Peng , Ananth Sudha , Gaur Pankaj , Gittelman Rachel M. , Yusko Erik , Sanders Catherine , Robins Harlan , Hammond Scott A. , Janik John E. , Mkrtichyan Mikayel , Gupta Seema , Khleif Samir N.
Published: April 2023

Supplementary Figure Legends
Supplementary Fig. S1-S8 from LIN28/let-7/PD-L1 Pathway as a Target for Cancer Immunotherapy
Authors: Chen Yanlian , Xie Chen , Zheng Xiaohui , Nie Xin , Wang Zining , Liu Haiying , Zhao Yong
Published: April 2023

Figure S1.Inverse correlation between let-7e and PD-L1 expression. Figure S2.Let-7 suppresses PD-L1 expression. Figure S3.LIN28 mediates PD-L1 expression and does not directly promote PD-L1 transcription. Figure S4.C1632 suppresses PD-L1 expression in mouse cancer cells. Figure S5.C1632 suppresses PD-L1 expression and this inhibitory effect is rescued by LIN28 overexpression. Figure S6.LIN28 inhibitor suppresses cell growth in a variety of cancer cell lines. Figure S7.Depletion of PD-L1 by shRNA suppresses the proliferation of TUBO cancer cells. Figure S8.LIN28/let-7 axis regulates PD-L1 expression of THP-1 macrophages.
Table S1 from Response to Immune Checkpoint Inhibition in Two Patients with Alveolar Soft-Part Sarcoma
Authors: Lewin Jeremy , Davidson Scott , Anderson Nathaniel D. , Lau Beatrice Y. , Kelly Jacalyn , Tabori Uri , Salah Samer , Butler Marcus O. , Aung Kyaw L. , Shlien Adam , Dickson Brendan C. , Abdul Razak Albiruni R.
Published: April 2023

Patient Characteristics
Supplementary Figure Legends from Combination Therapy Using Ruxolitinib and Oncolytic HSV Renders Resistant MPNSTs Susceptible to Virotherapy
Authors: Ghonime Mohammed G. , Cassady Kevin A.
Published: April 2023

Supplementary Table 1: Nomenclature of oncolytic HSV-1 and their genetics; Supplementary Figure 1: RUX does not impair 67C-4 MPNST tumor cell growth; Supplementary Figure 2: Viral replication is integral to RUX/C134 anti-tumor effect.; Supplementary Figure 3: Combined RUX and C134 treatment effect on the infiltrating lymphocytes; Supplementary Figure 4: Virus treatment increases CD8 activation in the periphery (D3) and combination therapy maintains the activation (D5); Supplementary Figure 5: 67C-4 tumor cells express EphA2 and control peptide doesn't induce CD8 T cell activation.
Supplemental Figure Legends from IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells
Authors: Clancy-Thompson Eleanor , Ali Lestat , Bruck Patrick T. , Exley Mark A. , Blumberg Richard S. , Dranoff Glenn , Dougan Michael , Dougan Stephanie K.
Published: April 2023

Figure legends
Figure S2 from IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells
Authors: Clancy-Thompson Eleanor , Ali Lestat , Bruck Patrick T. , Exley Mark A. , Blumberg Richard S. , Dranoff Glenn , Dougan Michael , Dougan Stephanie K.
Published: April 2023

S2: IAP antagonist treatment skewsT-cell development toward the CD8 lineage in fetal thymic organ culture (FTOC).
Supplementary Data from Targeting Tissue Factor for Immunotherapy of Triple-Negative Breast Cancer Using a Second-Generation ICON
Authors: Hu Zhiwei , Shen Rulong , Campbell Amanda , McMichael Elizabeth , Yu Lianbo , Ramaswamy Bhuvaneswari , London Cheryl A. , Xu Tian , Carson William E.
Published: April 2023

S1. Tissue factor expression on TNBC and non-TNBC lines with BRCA1/2-wild type or mutation by flow cytometry assay. S2. TF expression is detected on the TNBC cancer cells and tumor vascular endothelial cells, but not on adjacent normal tissues, on TNBC CDX and PDX tumors. S3. Immunohistochemical (IHC) staining for TF and CD31 expression on paraffin-embedded whole TNBC tissues and tissue-microarray slides (TMA). S4. Schematic structures of tissue factor-targeting second-generation ICONs (murine and human L-ICON1s) and their binding activities to human and murine breast cancer cells. S5. Coagulation activities of L-ICON1 and ICON determined by Factor VII Human Chromogenic Activity Assay. S6. Generation of a murine breast cancer line 4T1 stably expressing luciferase (Luc) and green fluorescent protein (GFP) and an orthotopic mouse model of murine TNBC. Table S1. Coagulation activities (IU/ml, mean {plus minus} SD) of L-ICON1, ICON(WT) and ICON(K341A). S2. Protein concentrations of L-ICON1 and ICON in vitro in 4-day cell culture serum free medium of adenoviral vector-infected human TNBC MDA-MB231 line and in vivo in mouse plasma two days after last intratumoral injection of Ad vectors in an orthotopic SCID mouse model of human MDA-MB-231 tumor xenograft.
Figure S7 from Cripto-1 Plasmid DNA Vaccination Targets Metastasis and Cancer Stem Cells in Murine Mammary Carcinoma
Authors: Witt Kristina , Ligtenberg Maarten A. , Conti Laura , Lanzardo Stefania , Ruiu Roberto , Wallmann Tatjana , Tufvesson-Stiller Helena , Chambers Benedict J. , Rolny Charlotte , Lladser Alvaro , Lundqvist Andreas , Cavallo Federica , Kiessling Rolf
Published: April 2023

Cripto-1 expression on TUBO P3 cells.
Figure S4 from Cripto-1 Plasmid DNA Vaccination Targets Metastasis and Cancer Stem Cells in Murine Mammary Carcinoma
Authors: Witt Kristina , Ligtenberg Maarten A. , Conti Laura , Lanzardo Stefania , Ruiu Roberto , Wallmann Tatjana , Tufvesson-Stiller Helena , Chambers Benedict J. , Rolny Charlotte , Lladser Alvaro , Lundqvist Andreas , Cavallo Federica , Kiessling Rolf
Published: April 2023

Western blot analysis of Cripto-1 expression in BALB-neuT primary lesions.
Figure S3 from Cripto-1 Plasmid DNA Vaccination Targets Metastasis and Cancer Stem Cells in Murine Mammary Carcinoma
Authors: Witt Kristina , Ligtenberg Maarten A. , Conti Laura , Lanzardo Stefania , Ruiu Roberto , Wallmann Tatjana , Tufvesson-Stiller Helena , Chambers Benedict J. , Rolny Charlotte , Lladser Alvaro , Lundqvist Andreas , Cavallo Federica , Kiessling Rolf
Published: April 2023

Cytotoxicity of pre-activated NK cells against 4T1 cell line.
Figure S7 from High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model
Authors: Richman Sarah A. , Nunez-Cruz Selene , Moghimi Babak , Li Lucy Z. , Gershenson Zachary T. , Mourelatos Zissimos , Barrett David M. , Grupp Stephan A. , Milone Michael C.
Published: April 2023

Slides of brain tissue from 129X1/SvJ mice that received syngeneic CAR T cells expressing the E101K-CD28-CD3ï�º CAR were stained with anti-mouse CD3 by IHC. Left field, cerebellar parenchymal blood vessel, 20x. Right three panels, cerebellar regions with associated meninges.
Figure S5 from High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model
Authors: Richman Sarah A. , Nunez-Cruz Selene , Moghimi Babak , Li Lucy Z. , Gershenson Zachary T. , Mourelatos Zissimos , Barrett David M. , Grupp Stephan A. , Milone Michael C.
Published: April 2023

CD8 IHC on spinal cord from mice receiving indicated CAR T cells.
Supplementary Figure S6 from Interleukin 33 Signaling Restrains Sporadic Colon Cancer in an Interferon-γ–Dependent Manner
Authors: Eissmann Moritz F. , Dijkstra Christine , Wouters Merridee A. , Baloyan David , Mouradov Dmitri , Nguyen Paul M. , Davalos-Salas Mercedes , Putoczki Tracy L. , Sieber Oliver M. , Mariadason John M. , Ernst Matthias , Masson Frederick
Published: April 2023

Fig S6. St2-deficiency did not alter Treg frequency in untreated naïve colons.
Figure S3 from High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model
Authors: Richman Sarah A. , Nunez-Cruz Selene , Moghimi Babak , Li Lucy Z. , Gershenson Zachary T. , Mourelatos Zissimos , Barrett David M. , Grupp Stephan A. , Milone Michael C.
Published: April 2023

Rate of tumor growth by BLI through day 17 post-tumor injection depicted as slopes of the log-transformed total flux from mice in Figure 4. Time-points past day 17 were excluded from this analysis due to the significant loss of mice after this time point due to toxicity in the E101K group. Populations were compared using a one-way ANOVA with a threshold p value of < 0.05 and post-hoc analysis using Tukey's multiple comparisons test. NS=not significant.
Supplementary Figure S4 from Interleukin 33 Signaling Restrains Sporadic Colon Cancer in an Interferon-γ–Dependent Manner
Authors: Eissmann Moritz F. , Dijkstra Christine , Wouters Merridee A. , Baloyan David , Mouradov Dmitri , Nguyen Paul M. , Davalos-Salas Mercedes , Putoczki Tracy L. , Sieber Oliver M. , Mariadason John M. , Ernst Matthias , Masson Frederick
Published: April 2023

Fig S4. St2 is expressed by colon-derived mesenchymal cells.
Figure S1 from High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model
Authors: Richman Sarah A. , Nunez-Cruz Selene , Moghimi Babak , Li Lucy Z. , Gershenson Zachary T. , Mourelatos Zissimos , Barrett David M. , Grupp Stephan A. , Milone Michael C.
Published: April 2023

Comparison of surface expression of CAR constructs used in these studies. T cells were transduced with indicated lentivirus at an MOI of 5. At day 8 of expansion, T cells were stained with anti-mouse antibody that recognizes the mouse scFv.
Supplementary figures legend from Disruption of IFN-I Signaling Promotes HER2/Neu Tumor Progression and Breast Cancer Stem Cells
Authors: Castiello Luciano , Sestili Paola , Schiavoni Giovanna , Dattilo Rosanna , Monque Domenica M. , Ciaffoni Fiorella , Iezzi Manuela , Lamolinara Alessia , Sistigu Antonella , Moschella Federica , Pacca Anna Maria , Macchia Daniele , Ferrantini Maria , Zeuner Ann , Biffoni Mauro , Proietti Enrico , Belardelli Filippo , Aricò Eleonora
Published: April 2023

Legends of supplementary figures
Supplementary Figure 1 from Disruption of IFN-I Signaling Promotes HER2/Neu Tumor Progression and Breast Cancer Stem Cells
Authors: Castiello Luciano , Sestili Paola , Schiavoni Giovanna , Dattilo Rosanna , Monque Domenica M. , Ciaffoni Fiorella , Iezzi Manuela , Lamolinara Alessia , Sistigu Antonella , Moschella Federica , Pacca Anna Maria , Macchia Daniele , Ferrantini Maria , Zeuner Ann , Biffoni Mauro , Proietti Enrico , Belardelli Filippo , Aricò Eleonora
Published: April 2023

Immunophenotypic characterization of lymphoid districts populations in WT or tumor-bearing Her2/neu transgenic mice, in the presence or absence of a functional IFN-I system
Table S4 from Allelic Polymorphisms of KIRs and HLAs Predict Favorable Responses to Tyrosine Kinase Inhibitors in CML
Authors: Ureshino Hiroshi , Shindo Takero , Kojima Hiroto , Kusunoki Yasushi , Miyazaki Yuki , Tanaka Hidenori , Saji Hiroh , Kawaguchi Atsushi , Kimura Shinya
Published: April 2023

Definitions and distribution of avidity between KIR3DL1 and HLA-B
Table S3 from Treatment-Related Adverse Events Predict Improved Clinical Outcome in NSCLC Patients on KEYNOTE-001 at a Single Center
Authors: Lisberg Aaron , Tucker D. Andrew , Goldman Jonathan W. , Wolf Brian , Carroll James , Hardy Ariana , Morris Karolyn , Linares Paulina , Adame Carlos , Spiegel Marshall L. , Wells Courtney , McKenzie Jordan , Ledezma Blanca , Mendenhall Melody , Abarca Phillip , Bornazyan Krikor , Hunt Jaime , Moghadam Nima , Chong Natalie , Nameth Danielle , Marx Caitlin , Madrigal John , Vangala Sitaram , Shaverdian Narek , Elashoff David , Garon Edward B.
Published: April 2023

Table S3: The occurrence of a treatment related AE (trAE) in the 97 patients treated at UCLA on the KEYNOTE-001 clinical trial, stratified by a history of thoracic radiation therapy (TRT) or prior radiation therapy to any location. P values computed via Fisher's exact test.
Supplementary Figure S7 from Stromal Fibroblasts Mediate Anti–PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma
Authors: Zhao Fei , Evans Kathy , Xiao Christine , DeVito Nicholas , Theivanthiran Balamayooran , Holtzhausen Alisha , Siska Peter J. , Blobe Gerard C. , Hanks Brent A.
Published: April 2023

Impact of delayed TGFbeta inhibition following anti-PD-1 escape.
Supplemental Figure 2 from Primary T Cells from Cutaneous T-cell Lymphoma Skin Explants Display an Exhausted Immune Checkpoint Profile
Authors: Querfeld Christiane , Leung Samantha , Myskowski Patricia L. , Curran Shane A. , Goldman Debra A. , Heller Glenn , Wu Xiwei , Kil Sung Hee , Sharma Sneh , Finn Kathleen J. , Horwitz Steven , Moskowitz Alison , Mehrara Babak , Rosen Steven T. , Halpern Allan C. , Young James W.
Published: April 2023

Sections show morphologic and immunohistochemical findings of MF lesion
Supplementary Figure S4 from Stromal Fibroblasts Mediate Anti–PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma
Authors: Zhao Fei , Evans Kathy , Xiao Christine , DeVito Nicholas , Theivanthiran Balamayooran , Holtzhausen Alisha , Siska Peter J. , Blobe Gerard C. , Hanks Brent A.
Published: April 2023

BRAF-PTEN/MAF cell line validation by Western blot. Impact of MAFs on melanoma gene expression based on qrt-PCR. TGFbeta blockade effect on TBR1 and TBRII gene expression based on qrt-PCR.
Supplementary Figure S1 from Stromal Fibroblasts Mediate Anti–PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma
Authors: Zhao Fei , Evans Kathy , Xiao Christine , DeVito Nicholas , Theivanthiran Balamayooran , Holtzhausen Alisha , Siska Peter J. , Blobe Gerard C. , Hanks Brent A.
Published: April 2023

TGFbeta inhibition augments the efficacy of anti-CTLA-4 antibody immunotherapy.
Supplementary Tables and Figures from Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs
Authors: Diamond Julie M. , Vanpouille-Box Claire , Spada Sheila , Rudqvist Nils-Petter , Chapman Jessica R. , Ueberheide Beatrix M. , Pilones Karsten A. , Sarfraz Yasmeen , Formenti Silvia C. , Demaria Sandra
Published: April 2023

Table S1, Table S2, Figure S1, Figure S2
LFQ-MS Proteomics Data from Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs
Authors: Diamond Julie M. , Vanpouille-Box Claire , Spada Sheila , Rudqvist Nils-Petter , Chapman Jessica R. , Ueberheide Beatrix M. , Pilones Karsten A. , Sarfraz Yasmeen , Formenti Silvia C. , Demaria Sandra
Published: April 2023

Proteomics profiles of UT-TEX and RT-TEX
Supplemental Figures and Tables from Radiotherapy and CTLA-4 Blockade Shape the TCR Repertoire of Tumor-Infiltrating T Cells
Authors: Rudqvist Nils-Petter , Pilones Karsten A. , Lhuillier Claire , Wennerberg Erik , Sidhom John-William , Emerson Ryan O. , Robins Harlan S. , Schneck Jonathan , Formenti Silvia C. , Demaria Sandra
Published: April 2023

Figure S1. Relative composition of TCRs in unsorted tumors within each treatment group. Figure S2. TCRβ CDR3 sequence distance among AH1-pentamer+/tetramer+CD8+ T cells. Table S1. Summary of TCR sequencing of whole 4T1 tumors. Table S2. Summary of TCR sequencing of AH1-pentamer+CD8+ T cells. Table S3. Abundance of AH1 clone signature (amino acid sequences) in CD4+ or CD8+ sorted T cells. Table S4. Three AH1 reactive T cell clones were shared between 4T1 tumors and AH1 peptide-vaccinated animals.
Supplementary Tables from Exosomes Released from Tumor-Associated Macrophages Transfer miRNAs That Induce a Treg/Th17 Cell Imbalance in Epithelial Ovarian Cancer
Authors: Zhou Jieru , Li Xiaoduan , Wu Xiaoli , Zhang Ting , Zhu Qinyi , Wang Xinjing , Wang Husheng , Wang Kai , Lin Yingying , Wang Xipeng
Published: April 2023

2. This file contains supplemental table S1-S5. It shows univariate/multivariable analysis of OS in EOC patients, the absolute counts of Treg/Th17 cells in flow cytometric analysis, and the proportion of cytokines from Tregs/Th17 cells in flow cytometric analysis.
Figure 6S from Combination Therapy for Treating Advanced Drug-Resistant Acute Lymphoblastic Leukemia
Authors: Vicioso Yorleny , Gram Hermann , Beck Rose , Asthana Abhishek , Zhang Keman , Wong Derek P. , Letterio John , Parameswaran Reshmi
Published: April 2023

Supp. Fig. 6 EW-7197 treatment increases VAY736 induced NK cell mediated ADCC of ALL cells in vivo A, Percentages of CD16+ NK cells in bone marrow and spleen of mice from Figure.6C-E. B, Normalized weight in grams (spleen weight/mouse weight) and representative images of spleens from control and treated mice on day 42 from PT-4 transplanted mice treated as indicated from Figure.6FÃ,Â­H. Data are shown as mean {plus minus} SD of n=4-6 mice/ group. ** p<0.01;*** p<0.001;Ã�Â¾ **** p<0.0001 compared to controls by two-tailed Student t test. Experiments done with 3 technical replicates. E, Scheme showing VAY736 induced NK cell mediated ADCC of B-ALL cells, TGF-beta mediated inhibition of CD16 and ADCC, inhibition of TGF-beta receptor 1 on NK cells using EW-7197 enhances NK cell mediated ADCC.
Figure 5S from Combination Therapy for Treating Advanced Drug-Resistant Acute Lymphoblastic Leukemia
Authors: Vicioso Yorleny , Gram Hermann , Beck Rose , Asthana Abhishek , Zhang Keman , Wong Derek P. , Letterio John , Parameswaran Reshmi
Published: April 2023

Supp. Fig. 5 EW-7197 treatment increases VAY736 induced NK cell mediated ADCC of ALL cells in vivo A, Mouse TGF-beta Elisa using serum from PBS or ALL (PT-3) i.v. injected mice on day 35. B, Normalized weight (spleen weight/mouse weight) and representative images of spleens from control (PBS) and treated mice groups on day 35 from PT-3 transplanted mice treated as indicated from Figure.6C-E. Data are shown as mean {plus minus} SD of n=4-6 mice/ group. ** p<0.01;*** p<0.001;Ã�Â¾ **** p<0.0001 compared to controls by two-tailed Student t test. Experiments done with 3 technical replicates.
Figure 4S from Combination Therapy for Treating Advanced Drug-Resistant Acute Lymphoblastic Leukemia
Authors: Vicioso Yorleny , Gram Hermann , Beck Rose , Asthana Abhishek , Zhang Keman , Wong Derek P. , Letterio John , Parameswaran Reshmi
Published: April 2023

Supp. Fig. 4 Detection of NK cells in vivo A, Representative Dot plots of gated live cells based on FSCÃ,Â­A and SSCÃ,Â­A and CD19+CD10+ cells in the bone marrow and spleen of NSG mice treated with PBS (left) or 2x106 PTÃ,Â­3 ALL cells (right) on day 31. B, Normalized weight in grams (spleen weight/mouse weight) and picture of spleen from mice treatment groups from Figure 4AÃ,Â­C. C, Percentages CD56+CD3Ã,Â­ NK cells in bone marrow and spleen of NK alone and NK + VAY736 treated mice at day 31. Experiments done with 3 technical replicates.
Supplementary Table 1 from A Gene Signature Predicting Natural Killer Cell Infiltration and Improved Survival in Melanoma Patients
Authors: Cursons Joseph , Souza-Fonseca-Guimaraes Fernando , Foroutan Momeneh , Anderson Ashley , Hollande Frédéric , Hediyeh-Zadeh Soroor , Behren Andreas , Huntington Nicholas D. , Davis Melissa J.
Published: April 2023

Official gene symbols (HGNC) for our 20 NK signature genes and a subset of the results leading to their inclusion during curation, in particular bulk RNA-seq differential expression results and comparison to T cells for single-cell RNA-seq data from Tirosh et al (2016). For further details please refer to the Materials and Methods. LM22: CIBERSORT LM22 lists; LM7: Tosolini et al LM7 list.
Supplementary Figures 1-9 and Table 2 from A Gene Signature Predicting Natural Killer Cell Infiltration and Improved Survival in Melanoma Patients
Authors: Cursons Joseph , Souza-Fonseca-Guimaraes Fernando , Foroutan Momeneh , Anderson Ashley , Hollande Frédéric , Hediyeh-Zadeh Soroor , Behren Andreas , Huntington Nicholas D. , Davis Melissa J.
Published: April 2023

Supplementary Figures 1-9, & Supplementary Table 2.
Supplementary Figures 6-7 from A High-Avidity T-cell Receptor Redirects Natural Killer T-cell Specificity and Outcompetes the Endogenous Invariant T-cell Receptor
Authors: Landoni Elisa , Smith Christof C. , Fucá Giovanni , Chen Yuhui , Sun Chuang , Vincent Benjamin G. , Metelitsa Leonid S. , Dotti Gianpietro , Savoldo Barbara
Published: April 2023

Supplementary Figures and legends for Figures S6-S7
Supplementary Figures 1-5 from A High-Avidity T-cell Receptor Redirects Natural Killer T-cell Specificity and Outcompetes the Endogenous Invariant T-cell Receptor
Authors: Landoni Elisa , Smith Christof C. , Fucá Giovanni , Chen Yuhui , Sun Chuang , Vincent Benjamin G. , Metelitsa Leonid S. , Dotti Gianpietro , Savoldo Barbara
Published: April 2023

Supplementary figures and legends for Figures S1-S5
Supplementary Materials and Methods from Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor Models
Authors: Xiong Huizhong , Mittman Stephanie , Rodriguez Ryan , Pacheco-Sanchez Patricia , Moskalenko Marina , Yang Yagai , Elstrott Justin , Ritter Alex T. , Müller Sören , Nickles Dorothee , Arenzana Teresita L. , Capietto Aude-Hélène , Delamarre Lélia , Modrusan Zora , Rutz Sascha , Mellman Ira , Cubas Rafael
Published: April 2023

Additional material and methods
Table S5 from The Tumor Immune Microenvironment Drives a Prognostic Relevance That Correlates with Bladder Cancer Subtypes
Authors: Pfannstiel Carolin , Strissel Pamela L. , Chiappinelli Katherine B. , Sikic Danijel , Wach Sven , Wirtz Ralph M. , Wullweber Adrian , Taubert Helge , Breyer Johannes , Otto Wolfgang , Worst Thomas , Burger Maximilian , Wullich Bernd , Bolenz Christian , Fuhrich Nicole , Geppert Carol I. , Weyerer Veronika , Stoehr Robert , Bertz Simone , Keck Bastian , Erlmeier Franziska , Erben Philipp , Hartmann Arndt , Strick Reiner , Eckstein Markus
Published: April 2023

Distribution of stromal tumor infiltrating lymphocytes in analyzed cohorts and subgroups.
Table S3 from Cancer-Associated Fibroblasts Promote Immunosuppression by Inducing ROS-Generating Monocytic MDSCs in Lung Squamous Cell Carcinoma
Authors: Xiang Handan , Ramil Carlo P. , Hai Josephine , Zhang Chunsheng , Wang Huijun , Watkins Amanda A. , Afshar Roshi , Georgiev Peter , Sze Marc A. , Song Xuelei S. , Curran Patrick J. , Cheng Mangeng , Miller J. Richard , Sun Dongyu , Loboda Andrey , Jia Yanlin , Moy Lily Y. , Chi An , Brandish Philip E.
Published: April 2023

Supplementary table 3
Table S1 from The Tumor Immune Microenvironment Drives a Prognostic Relevance That Correlates with Bladder Cancer Subtypes
Authors: Pfannstiel Carolin , Strissel Pamela L. , Chiappinelli Katherine B. , Sikic Danijel , Wach Sven , Wirtz Ralph M. , Wullweber Adrian , Taubert Helge , Breyer Johannes , Otto Wolfgang , Worst Thomas , Burger Maximilian , Wullich Bernd , Bolenz Christian , Fuhrich Nicole , Geppert Carol I. , Weyerer Veronika , Stoehr Robert , Bertz Simone , Keck Bastian , Erlmeier Franziska , Erben Philipp , Hartmann Arndt , Strick Reiner , Eckstein Markus
Published: April 2023

Clinico-pathological features of analyzed cohorts and subgroups.
Supplementary Figure S1-S7 from The Tumor Immune Microenvironment Drives a Prognostic Relevance That Correlates with Bladder Cancer Subtypes
Authors: Pfannstiel Carolin , Strissel Pamela L. , Chiappinelli Katherine B. , Sikic Danijel , Wach Sven , Wirtz Ralph M. , Wullweber Adrian , Taubert Helge , Breyer Johannes , Otto Wolfgang , Worst Thomas , Burger Maximilian , Wullich Bernd , Bolenz Christian , Fuhrich Nicole , Geppert Carol I. , Weyerer Veronika , Stoehr Robert , Bertz Simone , Keck Bastian , Erlmeier Franziska , Erben Philipp , Hartmann Arndt , Strick Reiner , Eckstein Markus
Published: April 2023

Figure S1. Selected images of different sTILs amounts, illustration of applied scoring method and images of IHC stainings. Figure S2. TLS in MIBC Figure S3. Subtyping of the CCC-EMN cohort and the TCGA-Cohort according to the MDACC-subtyping gene signature Figure S4. TCGA-Basal tumors (n=142). CIBERSORT and Mutational Burden. Figure S5. TCGA Luminal tumors (n=243). CIBERSORT and Mutational Burden. Figure S6. Distribution of tumor mutational burden (TMB; based on total single nucleotide variants) and neoantigens among different cut-offs of stromal TILs. Figure S7. TCGA - Antigen presenting cell signature (AGPS) and combined adjuvant platinum-containing chemotherapy cohort.
Table S1 from Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
Authors: Zhao Qingchuan , Laverdure Jean-Philippe , Lanoix Joël , Durette Chantal , Côté Caroline , Bonneil Éric , Laumont Céline M. , Gendron Patrick , Vincent Krystel , Courcelles Mathieu , Lemieux Sébastien , Millar Douglas G. , Ohashi Pamela S. , Thibault Pierre , Perreault Claude
Published: April 2023

Table S1
Supplementary Figures from Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
Authors: Zhao Qingchuan , Laverdure Jean-Philippe , Lanoix Joël , Durette Chantal , Côté Caroline , Bonneil Éric , Laumont Céline M. , Gendron Patrick , Vincent Krystel , Courcelles Mathieu , Lemieux Sébastien , Millar Douglas G. , Ohashi Pamela S. , Thibault Pierre , Perreault Claude
Published: April 2023

Supplementary figures and legends
Supplementary Table 5. from Accumulation of Circulating CCR7+ Natural Killer Cells Marks Melanoma Evolution and Reveals a CCL19-Dependent Metastatic Pathway
Authors: Cristiani Costanza Maria , Turdo Alice , Ventura Valeria , Apuzzo Tiziana , Capone Mariaelena , Madonna Gabriele , Mallardo Domenico , Garofalo Cinzia , Giovannone Emilia Dora , Grimaldi Antonio M. , Tallerico Rossana , Marcenaro Emanuela , Pesce Silvia , Del Zotto Genny , Agosti Valter , Costanzo Francesco Saverio , Gulletta Elio , Rizzo Aroldo , Moretta Alessandro , Karre Klas , Ascierto Paolo A. , Todaro Matilde , Carbone Ennio
Published: April 2023

Univariate analysis sera cytokines from melanoma patients.
Supplementary Table 4. from Accumulation of Circulating CCR7+ Natural Killer Cells Marks Melanoma Evolution and Reveals a CCL19-Dependent Metastatic Pathway
Authors: Cristiani Costanza Maria , Turdo Alice , Ventura Valeria , Apuzzo Tiziana , Capone Mariaelena , Madonna Gabriele , Mallardo Domenico , Garofalo Cinzia , Giovannone Emilia Dora , Grimaldi Antonio M. , Tallerico Rossana , Marcenaro Emanuela , Pesce Silvia , Del Zotto Genny , Agosti Valter , Costanzo Francesco Saverio , Gulletta Elio , Rizzo Aroldo , Moretta Alessandro , Karre Klas , Ascierto Paolo A. , Todaro Matilde , Carbone Ennio
Published: April 2023

Univariate analysis of biomarkers identified by OPLS-DA.
Supplementary Table 1. from Accumulation of Circulating CCR7+ Natural Killer Cells Marks Melanoma Evolution and Reveals a CCL19-Dependent Metastatic Pathway
Authors: Cristiani Costanza Maria , Turdo Alice , Ventura Valeria , Apuzzo Tiziana , Capone Mariaelena , Madonna Gabriele , Mallardo Domenico , Garofalo Cinzia , Giovannone Emilia Dora , Grimaldi Antonio M. , Tallerico Rossana , Marcenaro Emanuela , Pesce Silvia , Del Zotto Genny , Agosti Valter , Costanzo Francesco Saverio , Gulletta Elio , Rizzo Aroldo , Moretta Alessandro , Karre Klas , Ascierto Paolo A. , Todaro Matilde , Carbone Ennio
Published: April 2023

Primary melanoma cell lines
Figure S3 from Human CD4+ T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain
Authors: Longino Natalie V. , Yang Junbao , Iyer Jayasri G. , Ibrani Dafina , Chow I-Ting , Laing Kerry J. , Campbell Victoria L. , Paulson Kelly G. , Kulikauskas Rima M. , Church Candice D. , James Eddie A. , Nghiem Paul , Kwok William W. , Koelle David M.
Published: April 2023

'CIS' epitope is restricted to HLA-DRB1*0401.
Table S3 from Phase II Trial of Ipilimumab with Stereotactic Radiation Therapy for Metastatic Disease: Outcomes, Toxicities, and Low-Dose Radiation–Related Abscopal Responses
Authors: Welsh James W. , Tang Chad , de Groot Patricia , Naing Aung , Hess Kenneth R. , Heymach John V. , Papadimitrakopoulou Vassiliki A. , Cushman Taylor R. , Subbiah Vivek , Chang Joe Y. , Simon George R. , Ramapriyan Rishab , Barsoumian Hampartsoum B. , Menon Hari , Cortez Maria Angelica , Massarelli Erminia , Nguyen Quynh , Sharma Padmanee , Allison James P. , Diab Adi , Verma Vivek , Raju Uma , Shaaban Sherif G. , Dadu Ramona , Cabanillas Maria E. , Wang Kelvin , Anderson Clark , Gomez Daniel R. , Hahn Stephen , Komaki Ritsuko , Hong David S.
Published: April 2023

Hepatic lesions measured at baseline for patients with evaluable imaging
Table S1 from Phase II Trial of Ipilimumab with Stereotactic Radiation Therapy for Metastatic Disease: Outcomes, Toxicities, and Low-Dose Radiation–Related Abscopal Responses
Authors: Welsh James W. , Tang Chad , de Groot Patricia , Naing Aung , Hess Kenneth R. , Heymach John V. , Papadimitrakopoulou Vassiliki A. , Cushman Taylor R. , Subbiah Vivek , Chang Joe Y. , Simon George R. , Ramapriyan Rishab , Barsoumian Hampartsoum B. , Menon Hari , Cortez Maria Angelica , Massarelli Erminia , Nguyen Quynh , Sharma Padmanee , Allison James P. , Diab Adi , Verma Vivek , Raju Uma , Shaaban Sherif G. , Dadu Ramona , Cabanillas Maria E. , Wang Kelvin , Anderson Clark , Gomez Daniel R. , Hahn Stephen , Komaki Ritsuko , Hong David S.
Published: April 2023

Patient characteristics
Supplementary Figure Legends from Activation of CD8+ T Cells Contributes to Antitumor Effects of CDK4/6 Inhibitors plus MEK Inhibitors
Authors: Teh Jessica L.F. , Erkes Dan A. , Cheng Phil F. , Tiago Manoela , Wilski Nicole A. , Field Conroy O. , Chervoneva Inna , Levesque Mitch P. , Xu Xiaowei , Dummer Reinhard , Aplin Andrew E.
Published: April 2023

Supplementary Figure Legends
Supplementary Table 2 from CAMK1D Triggers Immune Resistance of Human Tumor Cells Refractory to Anti–PD-L1 Treatment
Authors: Volpin Valentina , Michels Tillmann , Sorrentino Antonio , Menevse Ayse N. , Knoll Gertrud , Ditz Madlen , Milenkovic Vladimir M. , Chen Chih-Yeh , Rathinasamy Anchana , Griewank Klaus , Boutros Michael , Haferkamp Sebastian , Berneburg Mark , Wetzel Christian H. , Seckinger Anja , Hose Dirk , Goldschmidt Hartmut , Ehrenschwender Martin , Witzens-Harig Mathias , Szoor Arpad , Vereb Gyorgy , Khandelwal Nisit , Beckhove Philipp
Published: April 2023

Supplementary Table 2
Supplementary Figures from Metabolome of Pancreatic Juice Delineates Distinct Clinical Profiles of Pancreatic Cancer and Reveals a Link between Glucose Metabolism and PD-1+ Cells
Authors: Cortese Nina , Capretti Giovanni , Barbagallo Marialuisa , Rigamonti Alessandra , Takis Panteleimon G. , Castino Giovanni F. , Vignali Debora , Maggi Giulia , Gavazzi Francesca , Ridolfi Cristina , Nappo Gennaro , Donisi Greta , Erreni Marco , Avigni Roberta , Rahal Daoud , Spaggiari Paola , Roncalli Massimo , Cappello Paola , Novelli Francesco , Monti Paolo , Zerbi Alessandro , Allavena Paola , Mantovani Alberto , Marchesi Federica
Published: April 2023

Supplementary Figures
Figure S6 from Mammary Tumor Cells with High Metastatic Potential Are Hypersensitive to Macrophage-Derived HGF
Authors: Kitamura Takanori , Kato Yu , Brownlie Demi , Soong Daniel Y.H. , Sugano Gaël , Kippen Nicolle , Li Jiufeng , Doughty-Shenton Dahlia , Carragher Neil , Pollard Jeffrey W.
Published: April 2023

Detection and depletion of NK cells in mice with metastatic tumors.
Supplementary Video from Cross-dressing of CD8α+ Dendritic Cells with Antigens from Live Mouse Tumor Cells Is a Major Mechanism of Cross-priming
Authors: Das Mohapatra Alok , Tirrell Isaac , Bénéchet Alexandre P. , Pattnayak Shashmita , Khanna Kamal M. , Srivastava Pramod K.
Published: April 2023

Video
Figure S2 from Mammary Tumor Cells with High Metastatic Potential Are Hypersensitive to Macrophage-Derived HGF
Authors: Kitamura Takanori , Kato Yu , Brownlie Demi , Soong Daniel Y.H. , Sugano Gaël , Kippen Nicolle , Li Jiufeng , Doughty-Shenton Dahlia , Carragher Neil , Pollard Jeffrey W.
Published: April 2023

Correlation between candidate gene expression and metastasis-free survival of breast cancer patients.
Supplementary Data from CD39 Identifies the CD4+ Tumor-Specific T-cell Population in Human Cancer
Authors: Kortekaas Kim E. , Santegoets Saskia J. , Sturm Gregor , Ehsan Ilina , van Egmond Sylvia L. , Finotello Francesca , Trajanoski Zlatko , Welters Marij J.P. , van Poelgeest Mariette I.E. , van der Burg Sjoerd H.
Published: April 2023

Supplementary data
Supplementary Tables from Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF
Authors: Di Tacchio Mariangela , Macas Jadranka , Weissenberger Jakob , Sommer Kathleen , Bähr Oliver , Steinbach Joachim P. , Senft Christian , Seifert Volker , Glas Martin , Herrlinger Ulrich , Krex Dietmar , Meinhardt Matthias , Weyerbrock Astrid , Timmer Marco , Goldbrunner Roland , Deckert Martina , Scheel Andreas H. , Büttner Reinhard , Grauer Oliver M. , Schittenhelm Jens , Tabatabai Ghazaleh , Harter Patrick N. , Günther Stefan , Devraj Kavi , Plate Karl H. , Reiss Yvonne
Published: April 2023

File with supporting methods and tables
Supplementary Figure 2 from Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF
Authors: Di Tacchio Mariangela , Macas Jadranka , Weissenberger Jakob , Sommer Kathleen , Bähr Oliver , Steinbach Joachim P. , Senft Christian , Seifert Volker , Glas Martin , Herrlinger Ulrich , Krex Dietmar , Meinhardt Matthias , Weyerbrock Astrid , Timmer Marco , Goldbrunner Roland , Deckert Martina , Scheel Andreas H. , Büttner Reinhard , Grauer Oliver M. , Schittenhelm Jens , Tabatabai Ghazaleh , Harter Patrick N. , Günther Stefan , Devraj Kavi , Plate Karl H. , Reiss Yvonne
Published: April 2023

Supplementary Figure 2 illustrates PD-L1 expression in the GL261 glioma model
Supplementary Figure 1 from Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF
Authors: Di Tacchio Mariangela , Macas Jadranka , Weissenberger Jakob , Sommer Kathleen , Bähr Oliver , Steinbach Joachim P. , Senft Christian , Seifert Volker , Glas Martin , Herrlinger Ulrich , Krex Dietmar , Meinhardt Matthias , Weyerbrock Astrid , Timmer Marco , Goldbrunner Roland , Deckert Martina , Scheel Andreas H. , Büttner Reinhard , Grauer Oliver M. , Schittenhelm Jens , Tabatabai Ghazaleh , Harter Patrick N. , Günther Stefan , Devraj Kavi , Plate Karl H. , Reiss Yvonne
Published: April 2023

Supplementary Figure 1 showing PD-L1 expression in human GBM
Movie Legends from Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF
Authors: Di Tacchio Mariangela , Macas Jadranka , Weissenberger Jakob , Sommer Kathleen , Bähr Oliver , Steinbach Joachim P. , Senft Christian , Seifert Volker , Glas Martin , Herrlinger Ulrich , Krex Dietmar , Meinhardt Matthias , Weyerbrock Astrid , Timmer Marco , Goldbrunner Roland , Deckert Martina , Scheel Andreas H. , Büttner Reinhard , Grauer Oliver M. , Schittenhelm Jens , Tabatabai Ghazaleh , Harter Patrick N. , Günther Stefan , Devraj Kavi , Plate Karl H. , Reiss Yvonne
Published: April 2023

Legends for movies 1-4
Movie 4 from Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF
Authors: Di Tacchio Mariangela , Macas Jadranka , Weissenberger Jakob , Sommer Kathleen , Bähr Oliver , Steinbach Joachim P. , Senft Christian , Seifert Volker , Glas Martin , Herrlinger Ulrich , Krex Dietmar , Meinhardt Matthias , Weyerbrock Astrid , Timmer Marco , Goldbrunner Roland , Deckert Martina , Scheel Andreas H. , Büttner Reinhard , Grauer Oliver M. , Schittenhelm Jens , Tabatabai Ghazaleh , Harter Patrick N. , Günther Stefan , Devraj Kavi , Plate Karl H. , Reiss Yvonne
Published: April 2023

Aflibercept/AMG386 combined with anti-PD-1 therapy improves the vasculature as evidenced by desmin staining (CollagenIV, red; desmin, green)
Supplementary Figures 2-4 from Mediators of Inflammation-Driven Expansion, Trafficking, and Function of Tumor-Infiltrating MDSCs
Authors: Tannenbaum Charles S. , Rayman Patricia A. , Pavicic Paul G. , Kim Jin Sub , Wei Wei , Polefko Alexandra , Wallace Wesley , Rini Brian I. , Morris-Stiff Gareth , Allende Daniela S. , Hamilton Thomas , Finke James H. , Diaz-Montero C. Marcela
Published: April 2023

Supplementary Figures 2-4
Supplementary Data from Systemic Interferon-γ Increases MHC Class I Expression and T-cell Infiltration in Cold Tumors: Results of a Phase 0 Clinical Trial
Authors: Zhang Shihong , Kohli Karan , Black R. Graeme , Yao Lu , Spadinger Sydney M. , He Qianchuan , Pillarisetty Venu G. , Cranmer Lee D. , Van Tine Brian A. , Yee Cassian , Pierce Robert H. , Riddell Stanley R. , Jones Robin L. , Pollack Seth M.
Published: April 2023

Supplementary Tables 1-3 and Supplementary Tables 1-6
Supplementary Figures from Immunologic Profiling of Mutational and Transcriptional Subgroups in Pediatric and Adult High-Grade Gliomas
Authors: Bockmayr Michael , Klauschen Frederick , Maire Cecile L. , Rutkowski Stefan , Westphal Manfred , Lamszus Katrin , Schüller Ulrich , Mohme Malte
Published: April 2023

Supplementary Figures 1-4
Supplementary Data File S2 from Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy
Authors: Montfort Anne , Bertrand Florie , Rochotte Julia , Gilhodes Julia , Filleron Thomas , Milhès Jean , Dufau Carine , Imbert Caroline , Riond Joëlle , Tosolini Marie , Clarke Christopher J. , Dufour Florent , Constantinescu Andrei A. , Junior Nilton De França , Garcia Virginie , Record Michel , Cordelier Pierre , Brousset Pierre , Rochaix Philippe , Silvente-Poirot Sandrine , Therville Nicole , Andrieu-Abadie Nathalie , Levade Thierry , Hannun Yusuf A. , Benoist Hervé , Meyer Nicolas , Micheau Olivier , Colacios Céline , Ségui Bruno
Published: April 2023

Gating Strategies
Supplementary Table S1 from ASC Modulates CTL Cytotoxicity and Transplant Outcome Independent of the Inflammasome
Authors: Cheong Melody , Gartlan Kate H. , Lee Jason S. , Tey Siok-Keen , Zhang Ping , Kuns Rachel D. , Andoniou Christopher E. , Martins Jose Paulo , Chang Karshing , Sutton Vivien R. , Kelly Greg , Varelias Antiopi , Vuckovic Slavica , Markey Kate A. , Boyle Glen M. , Smyth Mark J. , Engwerda Christian R. , MacDonald Kelli P.A. , Trapani Joseph A. , Degli-Esposti Mariapia A. , Koyama Motoko , Hill Geoffrey R.
Published: April 2023

Supplementary Table S1 (related to Fig. 4A): (A) Ingenuity Pathway Analysis derived from the uncorrected dataset displaying top canonical signaling pathways involving differentially regulated genes in recipients as described in Fig.4A. (B) 10 selected immunologically relevant genes identified as differentially regulated in mice transplanted with B6.WT or B6.ASC-/- grafts.
Supplementary Figure S1 from ASC Modulates CTL Cytotoxicity and Transplant Outcome Independent of the Inflammasome
Authors: Cheong Melody , Gartlan Kate H. , Lee Jason S. , Tey Siok-Keen , Zhang Ping , Kuns Rachel D. , Andoniou Christopher E. , Martins Jose Paulo , Chang Karshing , Sutton Vivien R. , Kelly Greg , Varelias Antiopi , Vuckovic Slavica , Markey Kate A. , Boyle Glen M. , Smyth Mark J. , Engwerda Christian R. , MacDonald Kelli P.A. , Trapani Joseph A. , Degli-Esposti Mariapia A. , Koyama Motoko , Hill Geoffrey R.
Published: April 2023

Supplementary Figure S1: GVHD survival of lethally-irradiated (day 0, 1000cGy split dose) B6.WT, B6.ASC-/- or B6.NLRP3-/- recipients transplanted with BALB/c BM (5x106) and T cells (5x106). The non-GVHD control group received TCD BM cells (5x106) only. Results combined from 2 independent experiments (n = 20 per T cell-replete group, n = 8 for TCD BM group). ****P < 0.0001; B6.NLRP3-/- vs. B6.WT. Results are presented as means {plus minus} SEM.
Supplementary Table 4 from T Cells Expressing Receptor Recombination/Revision Machinery Are Detected in the Tumor Microenvironment and Expanded in Genomically Over-unstable Models
Authors: Morello Gaia , Cancila Valeria , La Rosa Massimo , Germano Giovanni , Lecis Daniele , Amodio Vito , Zanardi Federica , Iannelli Fabio , Greco Daniele , La Paglia Laura , Fiannaca Antonino , Urso Alfonso M. , Graziano Giulia , Ferrari Francesco , Pupa Serenella M. , Sangaletti Sabina , Chiodoni Claudia , Pruneri Giancarlo , Bardelli Alberto , Colombo Mario P. , Tripodo Claudio
Published: April 2023

Supplementary Table 4
Supplementary Figures 1-12 from MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions
Authors: Gkountidi Anastasia O. , Garnier Laure , Dubrot Juan , Angelillo Julien , Harlé Guillaume , Brighouse Dale , Wrobel Ludovic J. , Pick Robert , Scheiermann Christoph , Swartz Melody A. , Hugues Stéphanie
Published: April 2023

Supplementary Figures and Legends
Supplementary Tables from Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer
Authors: Emmons Tiffany R. , Giridharan Thejaswini , Singel Kelly L. , Khan ANM Nazmul H. , Ricciuti Jason , Howard Kaitlyn , Silva-Del Toro Stephanie L. , Debreceni Ivy L. , Aarts Cathelijn E.M. , Brouwer Mieke C. , Suzuki Sora , Kuijpers Taco W. , Jongerius Ilse , Allen Lee-Ann H. , Ferreira Viviana P. , Schubart Anna , Sellner Holger , Eder Jörg , Holland Steven M. , Ram Sanjay , Lederer James A. , Eng Kevin H. , Moysich Kirsten B. , Odunsi Kunle , Yaffe Michael B. , Zsiros Emese , Segal Brahm H.
Published: April 2023

Supplementary Tables 1-2
Supplementary Figure S2 from Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer
Authors: Emmons Tiffany R. , Giridharan Thejaswini , Singel Kelly L. , Khan ANM Nazmul H. , Ricciuti Jason , Howard Kaitlyn , Silva-Del Toro Stephanie L. , Debreceni Ivy L. , Aarts Cathelijn E.M. , Brouwer Mieke C. , Suzuki Sora , Kuijpers Taco W. , Jongerius Ilse , Allen Lee-Ann H. , Ferreira Viviana P. , Schubart Anna , Sellner Holger , Eder Jörg , Holland Steven M. , Ram Sanjay , Lederer James A. , Eng Kevin H. , Moysich Kirsten B. , Odunsi Kunle , Yaffe Michael B. , Zsiros Emese , Segal Brahm H.
Published: April 2023

Supplementary Figure S2: OC ascites fluid exposure increases neutrophil lifespan, increases the proportion of low-density neutrophils, increases LOX-1 expression, and induces neutrophil nuclear hypersegmentation
Supplementary Table S1 from Impact of TCR Diversity on the Development of Transplanted or Chemically Induced Tumors
Authors: Schreiber Karin , Karrison Theodore G. , Wolf Steven P. , Kiyotani Kazuma , Steiner Madeline , Littmann Eric R. , Pamer Eric G. , Kammertoens Thomas , Schreiber Hans , Leisegang Matthias
Published: April 2023

Supplementary Table S1
Supplementary Data from Impact of TCR Diversity on the Development of Transplanted or Chemically Induced Tumors
Authors: Schreiber Karin , Karrison Theodore G. , Wolf Steven P. , Kiyotani Kazuma , Steiner Madeline , Littmann Eric R. , Pamer Eric G. , Kammertoens Thomas , Schreiber Hans , Leisegang Matthias
Published: April 2023

Supplementary information containing Supplementary Methods, Supplementary References, Supplementary Figure 1, and Supplementary Figure 2.
Supplementary Figure Legends from CD4+ T-cell Immunity in the Peripheral Blood Correlates with Response to Anti-PD-1 Therapy
Authors: Kagamu Hiroshi , Kitano Shigehisa , Yamaguchi Ou , Yoshimura Kenichi , Horimoto Katsuhisa , Kitazawa Masashi , Fukui Kazuhiko , Shiono Ayako , Mouri Atsuhito , Nishihara Fuyumi , Miura Yu , Hashimoto Kosuke , Murayama Yoshitake , Kaira Kyoichi , Kobayashi Kunihiko
Published: April 2023

Supplementary Figure Legends
Figure S3 from Single-Cell Immune Competency Signatures Associate with Survival in Phase II GVAX and CRS-207 Randomized Studies in Patients with Metastatic Pancreatic Cancer
Authors: Nair Nitya , Chen Shih-Yu , Lemmens Ed , Chang Serena , Le Dung T. , Jaffee Elizabeth M. , Murphy Aimee , Whiting Chan , Müller Thomas , Brockstedt Dirk G.
Published: April 2023

Manual gating verification of immune cell subsets associated with clinical outcome at baseline, 7-and 10- weeks post treatment in the phase 2a training set
Supplementary Data from Prognostic Integrated Image-Based Immune and Molecular Profiling in Early-Stage Endometrial Cancer
Authors: Horeweg Nanda , de Bruyn Marco , Nout Remi A. , Stelloo Ellen , Kedzierska Katarzyna , León-Castillo Alicia , Plat Annechien , Mertz Kirsten D. , Osse Michelle , Jürgenliemk-Schulz Ina M. , Lutgens Ludy C.H.W. , Jobsen Jan J. , van der Steen-Banasik Elzbieta M. , Smit Vincent T. , Creutzberg Carien L. , Bosse Tjalling , Nijman Hans W. , Koelzer Viktor H. , Church David N.
Published: April 2023

Supplementary Tables 1-14 and Supplementary Figures 1-4
Supplementary Figures and Tables from IL6 Induces an IL22+ CD8+ T-cell Subset with Potent Antitumor Function
Authors: St. Paul Michael , Saibil Samuel D. , Lien Scott C. , Han SeongJun , Sayad Azin , Mulder David T. , Garcia-Batres Carlos R. , Elford Alisha R. , Israni-Winger Kavita , Robert-Tissot Céline , Zon Michael , Katz Sarah Rachel , Shaw Patricia A. , Clarke Blaise A. , Bernardini Marcus Q. , Nguyen Linh T. , Haibe-Kains Benjamin , Pugh Trevor J. , Ohashi Pamela S.
Published: April 2023

Supplemental Figures 1-9 and Supplementary Tables 1-3