bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimenting With Frequency‐And‐Angular Sounding to Characterize Traveling Ionospheric Disturbances Using the LWA‐SV Radio Telescope and A DPS4D
Authors: Obenberger K. S. , Dao E. , Dowell J.D.
Published: February 2019

Here we present near vertical angle of arrival and Doppler observations using a Digisonde Portable Sounder 4D (DPS4D) as a transmitter and the Long Wavelength Array at Sevilleta (LWA‐SV) radio telescope as a receiver, over an 80‐km baseline. With 256 dual‐polarization dipole antennas, LWA‐SV provides unparalleled sensitivity and angular resolution to high frequency sounding measurements of traveling ionospheric disturbances (TIDs). We conducted a study over 3 days in March 2018 and detected several TIDs ranging from 10‐ to 45‐min periods. These medium scale TIDs were detected using an implementation of frequency‐and‐angular sounding (FAS), which was first described in Beley et al. (1995, https://doi.org/10.1029/95RS01992). FAS assumes an ionospheric mirror model and provides estimates of the wavelength, direction, and speed of TIDs using the measured angle of arrival and Doppler of a high frequency ionospheric reflection. We experiment with this method and show that LWA‐SV is capable of achieving observations that are unmatched in sensitivity and resolution, allowing for measurements limited primarily by the errors accumulated by the assumptions within different manifestations of the FAS algorithm.
Using Color Coherence Vectors to Evaluate the Performance of Hydrologic Data Assimilation
Authors: Moslehi Mahsa , de Barros Felipe P. J.
Published: February 2019

An inadequate characterization of hydrogeological properties can significantly decrease the trustworthiness of subsurface flow and transport model predictions. A variety of data assimilation methods have been proposed in order to estimate hydrogeological parameters from spatially scarce data by incorporating them into the governing physical models. In order to quantify the accuracy of the estimations, several metrics have been used such as Rank Histograms, root‐mean‐square error (RMSE), and Ensemble Spread. However, these commonly used metrics do not regard the spatial correlation of the aquifer's properties. This can cause permeability fields with very different spatial structures to have similar histograms or RMSE. In this paper, we propose an approach based on color coherence vectors (CCV) for evaluating the performance of these estimation methods. CCV is a histogram‐based technique for comparing images that incorporate spatial information. We represent estimated fields as digital three‐channel images and use CCV to compare and quantify the accuracy of estimations. The appealing feature of this technique is that it considers the spatial structure embedded in the estimated fields. The sensitivity of CCV to spatial information makes it a suitable metric for assessing the performance of data assimilation techniques. Under various factors, such as numbers of measurements and structural parameters of the log conductivity field, we compare the performance of CCV with the RMSE.
Comparison of Contemporary In Situ, Model, and Satellite Remote Sensing Soil Moisture With a Focus on Drought Monitoring
Authors: Ford Trent W. , Quiring Steven M.
Published: February 2019

Soil moisture is a key drought indicator; however, current in situ soil moisture infrastructure is inadequate for large‐scale drought monitoring. One initiative of the ongoing National Soil Moisture Network program is the development of a near real‐time drought monitoring product that integrates in situ, model, and satellite remote sensing data. Data integration from diverse sources requires large‐scale validation prior to integration. This study develops a framework for assessing the fidelity of in situ, model, and satellite soil moisture data sets. Here we evaluate data from over 100 in situ monitoring stations that are part of nine monitoring networks; North American Land Data Assimilation System Phase 2 and Climate Prediction Center land surface models; and Soil Moisture Active‐Passive, Soil Moisture and Ocean Salinity, and European Space Agency‐Climate Change Initiative (ESA‐CCI) satellite products. The results indicate the majority of in situ stations exhibit low error variance and are spatially representative; however, some networks and individual stations exhibit anomalously high error variance or are sited in a way that make them not spatially representative of a larger area. Overall, North American Land Data Assimilation System Phase 2 is the modeled product that consistently performed best, and Soil Moisture Active‐Passive L3 is the remotely sensed product that consistently performed the best. They were able to both capture in situ soil moisture variability and provide an accurate depiction of drought conditions. The methods and verification framework applied in this study can be used to evaluate any soil moisture data set in any region of the world.
Soil Moisture Data Sets Become Fertile Ground for Applications
Authors: Shrestha Rupesh , Boyer Alison
Published: February 2019

An integrated data platform harmonizes many disparate soil moisture data sets to better inform disaster response planners, climate scientists and meteorologists, farmers, and others.
A chemical approach for global protein knockdown from mice to non-human primates
Authors: Sun Xiuyun , Wang Jun , Yao Xia , Zheng Wen , Mao Yang , Lan Tianlong , Wang Liguo , Sun Yonghui , Zhang Xinyi , Zhao Qiuye , Zhao Jianguo , Xiao Rui-Ping , Zhang Xiuqin , Ji Guangju , Rao Yu
Published: February 2019

Although conventional genetic modification approaches for protein knockdown work very successfully due to the increasing use of CRISPR/Cas9, effective techniques for achieving protein depletion in adult animals, especially in large animals such as non-human primates, are lacking. Here, we report a chemical approach based on PROTACs technology that efficiently and quickly knocks down FKBP12 (12-kDa FK506-binding) protein globally in vivo. Both intraperitoneal and oral administration led to rapid, robust, and reversible FKBP12 degradation in mice. The efficiency and practicality of this method were successfully demonstrated in both large and small animals (mice, rats, Bama pigs, and rhesus monkeys). Furthermore, we showed this approach can also be applied to effectively knockdown other target proteins such as Bruton's tyrosine kinase (BTK). This chemical protein knockdown strategy provides a powerful research tool for gene function studies in animals, particularly in large animals, for which gene-targeted knockout strategies may remain unfeasible.
Dynamics of the Bloch point in an asymmetric permalloy disk
Authors: Im Mi-Young , Han Hee-Sung , Jung Min-Seung , Yu Young-Sang , Lee Sooseok , Yoon Seongsoo , Chao Weilun , Fischer Peter , Hong Jung-Il , Lee Ki-Suk
Published: February 2019

A Bloch point (BP) is a topological defect in a ferromagnet at which the local magnetization vanishes. With the difficulty of generating a stable BP in magnetic nanostructures, the intrinsic nature of a BP and its dynamic behaviour has not been verified experimentally. We report a realization of steady-state BPs embedded in deformed magnetic vortex cores in asymmetrically shaped Ni80Fe20 nanodisks. Time-resolved nanoscale magnetic X-ray imaging combined with micromagnetic simulation shows detailed dynamic character of BPs, revealing rigid and limited lateral movements under magnetic field pulses as well as its crucial role in vortex-core dynamics. Direct visualizations of magnetic structures disclose the unique dynamical feature of a BP as an atomic scale discrete spin texture and allude its influence on the neighbouring spin structures such as magnetic vortices.
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats
Authors: Goto Teppei , Hara Hiromasa , Sanbo Makoto , Masaki Hideki , Sato Hideyuki , Yamaguchi Tomoyuki , Hochi Shinichi , Kobayashi Toshihiro , Nakauchi Hiromitsu , Hirabayashi Masumi
Published: February 2019

Regeneration of human kidneys in animal models would help combat the severe shortage of donors in transplantation therapy. Previously, we demonstrated by interspecific blastocyst complementation between mouse and rats, generation of pluripotent stem cell (PSC)-derived functional pancreas, in apancreatic Pdx1 mutant mice. We, however, were unable to obtain rat PSC-derived kidneys in anephric Sall1 mutant mice, likely due to the poor contribution of rat PSCs to the mouse metanephric mesenchyme, a nephron progenitor. Here, conversely, we show that mouse PSCs can efficiently differentiate into the metanephric mesenchyme in rat, allowing the generation of mouse PSC-derived kidney in anephric Sall1 mutant rat. Glomerular epithelium and renal tubules in the kidneys are entirely composed of mouse PSC-derived cells expressing key functional markers. Importantly, the ureter-bladder junction is normally formed. These data provide proof-of-principle for interspecific blastocyst complementation as a viable approach for kidney generation.
Permanent porous hydrogen-bonded frameworks with two types of Brønsted acid sites for heterogeneous asymmetric catalysis
Authors: Gong Wei , Chu Dandan , Jiang Hong , Chen Xu , Cui Yong , Liu Yan
Published: February 2019

The search for porous materials with strong Brønsted acid sites for challenging reactions has long been of significant interest, but it remains a formidable synthetic challenge. Here we demonstrate a cage extension strategy to construct chiral permanent porous hydrogen-bonded frameworks with strong Brønsted acid groups for heterogeneous asymmetric catalysis. We report the synthesis of two octahedral coordination cages using enantiopure 4,4’,6,6’-tetra(benzoate) ligand of 1,1’-spirobiindane-7,7’-phosphoric acid and Ni4/Co4-p-tert-butylsulfonylcalix[4]arene clusters. Intercage hydrogen-bonds and hydrophobic interactions betweentert-butyl groups direct the hierarchical assembly of the cages into a permanent porous material. The chiral phosphoric acid-containing frameworks can be high efficient and recyclable heterogeneous Brønsted acid catalysts for asymmetric [3+2] coupling of indoles with quinone monoimine and Friedel-Crafts alkylations of indole with aryl aldimines. The afforded enantioselectivities (up to 99.9% ee) surpass those of the homogeneous counterparts and compare favorably with those of the most enantioselective homogeneous phosphoric acid catalysts reported to date.
Selection rules for all-optical magnetic recording in iron garnet
Authors: Stupakiewicz A. , Szerenos K. , Davydova M. D. , Zvezdin K. A. , Zvezdin A. K. , Kirilyuk A. , Kimel A. V.
Published: February 2019

Rapid growth of the area of ultrafast magnetism has allowed to achieve a substantial progress in all-optical magnetic recording with femtosecond laser pulses and triggered intense discussions about microscopic mechanisms responsible for this phenomenon. The typically used metallic medium nevertheless considerably limits the applications because of the unavoidable heat dissipation. In contrast, the recently demonstrated photo-magnetic recording in transparent dielectric garnet for all practical purposes is dissipation-free. This discovery raised question about selection rules, i.e. the optimal wavelength and the polarization of light, for such a recording. Here we report the computationally and experimentally identified workspace of parameters allowing photo-magnetic recording in Co-doped iron garnet using femtosecond laser pulses. The revealed selection rules indicate that the excitations responsible for the coupling of light to spins are d-d electron transitions in octahedral and tetrahedral Co-sublattices, respectively.
Hidden structural and chemical order controls lithium transport in cation-disordered oxides for rechargeable batteries
Authors: Ji Huiwen , Urban Alexander , Kitchaev Daniil A. , Kwon Deok-Hwang , Artrith Nongnuch , Ophus Colin , Huang Wenxuan , Cai Zijian , Shi Tan , Kim Jae Chul , Kim Haegyeom , Ceder Gerbrand
Published: February 2019

Structure plays a vital role in determining materials properties. In lithium ion cathode materials, the crystal structure defines the dimensionality and connectivity of interstitial sites, thus determining lithium ion diffusion kinetics. In most conventional cathode materials that are well-ordered, the average structure as seen in diffraction dictates the lithium ion diffusion pathways. Here, we show that this is not the case in a class of recently discovered high-capacity lithium-excess rocksalts. An average structure picture is no longer satisfactory to understand the performance of such disordered materials. Cation short-range order, hidden in diffraction, is not only ubiquitous in these long-range disordered materials, but fully controls the local and macroscopic environments for lithium ion transport. Our discovery identifies a crucial property that has previously been overlooked and provides guidelines for designing and engineering cation-disordered cathode materials.
Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathy
Authors: Fichtman Boris , Zagairy Fadia , Biran Nitzan , Barsheshet Yiftah , Chervinsky Elena , Ben Neriah Ziva , Shaag Avraham , Assa Michael , Elpeleg Orly , Harel Amnon , Spiegel Ronen
Published: February 2019

Nuclear envelopathies comprise a heterogeneous group of diseases caused by mutations in genes encoding nuclear envelope proteins. Mutations affecting lamina-associated polypeptide 1 (LAP1) result in two discrete phenotypes of muscular dystrophy and progressive dystonia with cerebellar atrophy. We report 7 patients presenting at birth with severe progressive neurological impairment, bilateral cataract, growth retardation and early lethality. All the patients are homozygous for a nonsense mutation in the TOR1AIP1 gene resulting in the loss of both protein isoforms LAP1B and LAP1C. Patient-derived fibroblasts exhibit changes in nuclear envelope morphology and large nuclear-spanning channels containing trapped cytoplasmic organelles. Decreased and inefficient cellular motility is also observed in these fibroblasts. Our study describes the complete absence of both major human LAP1 isoforms, underscoring their crucial role in early development and organogenesis. LAP1-associated defects may thus comprise a broad clinical spectrum depending on the availability of both isoforms in the nuclear envelope throughout life.
Highly emissive excitons with reduced exchange energy in thermally activated delayed fluorescent molecules
Authors: Pershin Anton , Hall David , Lemaur Vincent , Sancho-Garcia Juan-Carlos , Muccioli Luca , Zysman-Colman Eli , Beljonne David , Olivier Yoann
Published: February 2019

Unlike conventional thermally activated delayed fluorescence chromophores, boron-centered azatriangulene-like molecules combine a small excited-state singlet-triplet energy gap with high oscillator strengths and minor reorganization energies. Here, using highly correlated quantum-chemical calculations, we report this is driven by short-range reorganization of the electron density taking place upon electronic excitation of these multi-resonant structures. Based on this finding, we design a series of π-extended boron- and nitrogen-doped nanographenes as promising candidates for efficient thermally activated delayed fluorescence emitters with concomitantly decreased singlet-triplet energy gaps, improved oscillator strengths and core rigidity compared to previously reported structures, permitting both emission color purity and tunability across the visible spectrum.
Author Correction: True equilibrium measurement of transcription factor-DNA binding affinities using automated polarization microscopy
Authors: Jung Christophe , Bandilla Peter , von Reutern Marc , Schnepf Max , Rieder Susanne , Unnerstall Ulrich , Gaul Ulrike
Published: February 2019

In the original version of this Article, equation three contained a sign error whereby the term RT was added when it should have been subtracted. This has now been corrected in the PDF and HTML versions of the Article.
Intrinsic valley Hall transport in atomically thin MoS2
Authors: Wu Zefei , Zhou Benjamin T. , Cai Xiangbin , Cheung Patrick , Liu Gui-Bin , Huang Meizhen , Lin Jiangxiazi , Han Tianyi , An Liheng , Wang Yuanwei , Xu Shuigang , Long Gen , Cheng Chun , Law Kam Tuen , Zhang Fan , Wang Ning
Published: February 2019

Electrons hopping in two-dimensional honeycomb lattices possess a valley degree of freedom in addition to charge and spin. In the absence of inversion symmetry, these systems were predicted to exhibit opposite Hall effects for electrons from different valleys. Such valley Hall effects have been achieved only by extrinsic means, such as substrate coupling, dual gating, and light illuminating. Here we report the first observation of intrinsic valley Hall transport without any extrinsic symmetry breaking in the non-centrosymmetric monolayer and trilayer MoS2, evidenced by considerable nonlocal resistance that scales cubically with local resistance. Such a hallmark survives even at room temperature with a valley diffusion length at micron scale. By contrast, no valley Hall signal is observed in the centrosymmetric bilayer MoS2. Our work elucidates the topological origin of valley Hall effects and marks a significant step towards the purely electrical control of valley degree of freedom in topological valleytronics.
First-principles-based prediction of yield strength in the RhIrPdPtNiCu high-entropy alloy
Authors: Yin Binglun , Curtin William A.
Published: February 2019

High-entropy alloys are random alloys with five or more components, often near equi-composition, that often exhibit excellent mechanical properties. Guiding the design of new materials across the wide composition space requires an ability to compute necessary underlying material parameters via ab initio methods. Here, density functional theory is used to compute the elemental misfit volumes, alloy lattice constant, elastic constants, and stable stacking fault energy in the fcc noble metal RhIrPdPtNiCu. These properties are then used in a recent theory for the temperature and strain-rate dependent yield strength. The parameter-free prediction of 583 MPa is in excellent agreement with the measured value of 527 MPa. This quantitative connection between alloy composition and yield strength, without any experimental input, motivates this general density functional theory-based methodological path for exploring new potential high-strength high-entropy alloys, in this and other alloy classes, with the chemical accuracy of first-principles methods.
Identification of the molecular relationship between intravenous leiomyomatosis and uterine myoma using RNA sequencing
Authors: Zhang Xu , Wu Liangcai , Xu Rongjian , Zhu Chengpei , Ma Guotao , Zhang Chaoji , Liu Xingrong , Zhao Haitao , Miao Qi
Published: February 2019

The purpose of this study was to explore the potential relationship between intravenous leiomyomatosis (IVL) and uterine myoma (UM) at the molecular level. RNA-sequencing was performed on IVL tumours, UM tumours, and adjacent normal uterine muscle. We compared the gene expression levels between IVL and normal uterine muscle, UM and normal uterine muscle, to identify differentially expressed genes (DEGs). Then we used Gene Ontology Enrichment Analysis to determine the functions of the DEGs and performed specimen cluster analysis. We obtained 98 DEGs between IVL and adjacent normal uterine muscle, and 61 DEGs between UM and adjacent normal uterine muscle. Functional enrichment of both IVL and UM DEGs showed that they are associated with hormone stimulus, extracellular matrix, and cell adhesion. Unsupervised clustering analysis showed that IVL and UM could not be separated completely. Among these dysregulated genes, we found that HOXA13 showed a distinct dysregulated status between IVL and UM. HOXA13 may therefore serves as a biomarker to distinguish IVL and UM. Our results showed that IVL and UM may have similar dysregulated gene networks. They may be closely related, and HOXA13 may serves as a biomarker to distinguish between IVL and UM.
Pharmacokinetic-Pharmacodynamic Modeling for Coptisine Challenge of Inflammation in LPS-Stimulated Rats
Authors: Hu Yingfan , Wang Li , Xiang Li , Wu Jiasi , Huang Wen’ge , Xu Chensi , Meng Xianli , Wang Ping
Published: February 2019

Pro-inflammatory factors are important indicators for assessing inflammation severity and drug efficacy. Coptisine has been reported to inhibit LPS-induced TNF-α and NO production. In this study, we aim to build a pharmacokinetic-pharmacodynamic model to quantify the coptisine time course and potency of its anti-inflammatory effect in LPS-stimulated rats. The plasma and lung coptisine concentrations, plasma and lung TNF-α concentrations, plasma NO concentration, and lung iNOS expression were measured in LPS-stimulated rats after intravenous injection of three coptisine doses. The coptisine disposition kinetics were described by a two-compartment model. The coptisine distribution process from the plasma to the lung was described by first-order dynamics. The dynamics of plasma TNF-α generation and elimination followed zero-order kinetics and the Michaelis-Menten equation. A first-order kinetic model described the TNF-α diffusion process from the plasma to the lung. A precursor-pool indirect response model was used to describe the iNOS and NO generation induced by TNF-α. The inhibition rates of TNF-α production by coptisine (54.73%, 26.49%, and 13.25%) calculated from the simulation model were close to the decline rates of the plasma TNF-α AUC (57.27%, 40.33%, and 24.98%, respectively). Coptisine suppressed plasma TNF-α generation in a linear manner, resulting in a cascading reduction of iNOS and NO. The early term TNF-α response to stimulation is a key factor in the subsequent inflammatory cascade. In conclusion, this comprehensive PK-PD model provided a rational explanation for the interlocking relationship among TNF-α, iNOS and NO production triggered by LPS and a quantitative evaluation method for inhibition of TNF-α production by coptisine.
SIX1 represses senescence and promotes SOX2-mediated cellular plasticity during tumorigenesis
Authors: De Lope Cristina , Martín-Alonso Samara , Auzmendi-Iriarte Jaione , Escudero Carmen , Mulet Isabel , Larrasa-Alonso Javier , López-Antona Irene , Matheu Ander , Palmero Ignacio
Published: February 2019

Six1 is a developmental transcriptional regulator frequently overexpressed in human tumors. Recent results show that SIX1 also acts as a repressor of cell senescence, an antiproliferative response with a key role in tumor suppression, among other physiological and pathological settings. Here, we set to study the impact of SIX1 gain of function in transformation and tumorigenesis of fibroblasts, in connection with senescence. Using transcriptomic, histological, and functional analyses in murine tumors and cells of fibroblast origin, we show that SIX1 has a strong pro-tumorigenic action in this model, linked to the repression of a senescence-related gene signature and the induction of an undifferentiated phenotype mediated, at least in part, by the regulation of the stemness factor Sox2. Moreover, functional analyses with human glioma cell lines also show that SIX1 controls SOX2 expression, senescence and self-renewal in this model. Collectively, our results support a general link of SIX1 with senescence and SOX2-mediated cell plasticity in tumors.
A statistical tool for comparing seasonal ILI surveillance data
Authors: Ferland René , Froda Sorana
Published: February 2019

In this paper, we consider the yearly influenza epidemic, as reflected in the seasonal surveillance data compiled by the CDC (Center for Disease Control and Prevention, USA) and we explore a new methodology for comparing specific features of these data. In particular, we focus on the ten HHS (Health and Human Services) regions, and how the incidence data evolves in these regions. In order to perform the comparisons, we consider the relative distribution of weekly new cases over one season and replace the crude data with predicted values. These predictions are obtained after fitting a negative binomial regression model that controls for important covariates. The prediction is computed on a ‘generic’ set of covariate values that takes into account the relative size (population wise) of the regions to be compared. The main results are presented in graphical form, that quickly emphasizes relevant features of the seasonal data and facilitates the comparisons.
Immunotherapeutic advances in gastrointestinal malignancies
Authors: Rao Devika , Parakrama Ruwan , Augustine Titto , Liu Qiang , Goel Sanjay , Maitra Radhashree
Published: February 2019

Cancer is an important global issue with increasing incidence and mortality, placing a substantial burden on the healthcare system. Colorectal cancer is the third most common cancer diagnosed among men and women in US. It is estimated that in 2018 there will be 319,160 new diagnosis and 160,820 deaths related to cancer of the digestive system including both genders in the United States alone. Considering limited success of chemotherapy, radiotherapy, and surgery in treatment of these cancer patients, new therapeutic avenues are under constant investigation. Therapy options have consistently moved away from typical cytotoxic chemotherapy where patients with a given type and stage of the disease were treated similarly, to an individualized approach where a tumor is defined by its specific tissue characteristics /epigenetic profile, protein expression and genetic mutations. This review takes a deeper look at the immune-biological aspects of cancers in the gastrointestinal tract (entire digestive tract extending from esophagus/stomach to rectum, including pancreatico-biliary apparatus) and discusses the different treatment modalities that are available or being developed to target the immune system for better disease outcome.
Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters
Authors: Wei Yong , Xiong Zi Jian , Li Jun , Zou Chunxia , Cairo Christopher W. , Klassen John S. , Privé Gilbert G.
Published: February 2019

EPDR1, a member of the ependymin-related protein family, is a relatively uncharacterized protein found in the lysosomes and secretomes of most vertebrates. Despite having roles in human disease and health, the molecular functions of EPDR1 remain unknown. Here, we present crystal structures of human EPDR1 and reveal that the protein adopts a fold previously seen only in bacterial proteins related to the LolA lipoprotein transporter. EPDR1 forms a homodimer with an overall shape resembling a half-shell with two non-overlapping hydrophobic grooves on the flat side of the hemisphere. EPDR1 can interact with membranes that contain negatively charged lipids, including BMP and GM1, and we suggest that EPDR1 may function as a lysosomal activator protein or a lipid transporter. A phylogenetic analysis reveals that the fold is more widely distributed than previously suspected, with representatives identified in all branches of cellular life.
Development of highly selective potentiometric thorium(iv) ion-selective electrode: exploration supported with optical and DFT analysis
Authors: Kumar R. Selva , Kumar S. K. Ashok , Vijayakrishna Kari , Sivaramakrishna Akella , Rao C. V. S. Brahmmananda , Sivaraman N. , Sahoo Suban K.
Published: February 2019

A new liquid membrane based on PVC composed of L as neutral ion carrier, NaTPB as lipophilic salt dissolved in DOP as plasticizer was developed for selective determination of Th4+.
DNA aptamer assemblies as fibroblast growth factor mimics and their application in stem cell culture
Authors: Ueki Ryosuke , Atsuta Saki , Ueki Ayaka , Hoshiyama Junya , Li Jingyue , Hayashi Yohei , Sando Shinsuke
Published: February 2019

A 76-mer single-stranded DNA acts as functional mimic of basic fibroblast growth factor (bFGF), one of the essential factors for stem cell culture.
The atomic structure of a MgCo2O4 nanoparticle for a positive electrode of a Mg rechargeable battery
Authors: Kitamura Naoto , Tanabe Yuhei , Ishida Naoya , Idemoto Yasushi
Published: February 2019

The atomic structure of a spinel-type MgCo2O4 nanoparticle was investigated by the reverse Monte Carlo modelling using X-ray and neutron total scattering data.
In situ synthesis of photoluminescence-quenching nanopaper for rapid and robust detection of pathogens and proteins
Authors: Liu Yucheng , Mao Guobin , Wang Wang , Tian Songbai , Ji Xinghu , Liu Meng , He Zhike
Published: February 2019

In this work, the electron transfer protein cytochrome c is innovatively embedded into cellulose paper to prepare photoluminescence-quenching nanopaper with a highly-efficient quenching ability, rapid reaction time and long-term storage.
Anthranilamide (aam)-substituted arylboranes in direct carbon–carbon bond-forming reactions
Authors: Kamio Shintaro , Kageyuki Ikuo , Osaka Itaru , Yoshida Hiroto
Published: February 2019

Pd-Catalyzed cross-coupling and Rh-catalyzed 1,4-addition with Ar-B(aam) become feasible without the need for prior acidic deprotection
Co(ii)-cluster-based metal–organic frameworks as efficient heterogeneous catalysts for selective oxidation of arylalkanes
Authors: Fan Yanru , Li Xiao , Gao Kuan , Liu Yu , Meng Xiangru , Wu Jie , Hou Hongwei
Published: February 2019

Three Co-cluster-based metal–organic frameworks were designed and their catalytic activities for the selective oxidation of arylalkanes were explored.
Change of the kinetics of inclusion in cucurbit[7]uril upon hydrogenation and methylation of palmatine
Authors: Miskolczy Zsombor , Megyesi Mónika , Toke Orsolya , Biczók László
Published: February 2019

The negative activation entropy of tetrahydropalmatine inclusion makes the entry into cucurbit[7]uril significantly slower than in the case of dehydrocorydaline.
P-NIPAM in water–acetone mixtures: experiments and simulations
Authors: Pérez-Ramírez H. A. , Haro-Pérez C. , Vázquez-Contreras E. , Klapp J. , Bautista-Carbajal G. , Odriozola G.
Published: February 2019

The lower critical solution temperature (LCST) of poly-N-isopropylacrylamide (p-NIPAM) diminishes when a small volume of acetone is added to the aqueous polymer solution, and then increases for further additions, producing a minimum at a certain acetone concentration.
Kinetics of the reactions of NO3 radical with alkanes
Authors: Zhou Li , Ravishankara A. R. , Brown Steven S. , Zarzana Kyle J. , Idir Mahmoud , Daële Véronique , Mellouki Abdelwahid
Published: February 2019

The rate coefficients for the reactions of NO3 radicals with methane (CH4), ethane (C2H6), propane (C3H8), n-butane (n-C4H10), iso-butane (iso-C4H10), 2,3-dimethylbutane (C6H14), cyclopentane (C5H10) and cyclohexane (C6H12) at atmosphere pressure (1000 ± 5 hPa) and room temperature (298 ± 1.5 K) were measured using an absolute method.
Geometry and energetics of CO adsorption on hydroxylated UiO-66
Authors: Driscoll Darren M. , Troya Diego , Usov Pavel M. , Maynes Andrew J. , Morris Amanda J. , Morris John R.
Published: February 2019

Fundamental studies of CO adsorption on UiO-66 reveal adsorption occurs through interactions with the μ3-OH groups and once bound, CO binds through both the C- and O-end of the molecule.
Effects of a strong π-accepting ancillary ligand on the water oxidation activity of weakly coupled binuclear ruthenium catalysts
Authors: Matias Tiago A. , Rein Francisca N. , Rocha Reginaldo C. , Formiga André Luiz Barboza , Toma Henrique E. , Araki Koiti
Published: February 2019

A less positive RuIV/VO redox potential and lower water oxidation activity accounted for based on the spin density and oxyl character of [RuVO]3+ species.
Waterborne reduced graphene oxide dispersed bio-polyesteramide nanocomposites: an approach towards eco-friendly anticorrosive coatings
Authors: Irfan Mohd , Bhat Shahidul Islam , Ahmad Sharif
Published: February 2019

RGO dispersed waterborne soy polyester amide nanocomposites were formulated utilizing a solventless VOC free green approach for use as low cost anticorrosive coatings.
Ligand dechelation effect on a [Co(tpy)2]2+ scaffold towards electro-catalytic proton and water reduction
Authors: Majee Karunamay , Padhi Sumanta Kumar
Published: February 2019

This study presents the synthesis of the 4-(2,6-di(pyridin-2-yl)pyridin-4-yl)quinoline (4Ql-tpy) ligand and H2 evolution by corresponding cobalt complex, i.e. [Co(4Ql-tpy)2]Cl2.
Functionalizing benzothiadiazole with non-conjugating ester groups as side chains in a donor–acceptor polymer improves solar cell performance
Authors: Ratha Radhakrishna , Afroz Mohammad Adil , Gupta Ritesh Kant , Iyer Parameswar Krishnan
Published: February 2019

Side chain ester substitution on donor–acceptor based conjugated polymers used as solar harvesters in a bulk-heterojunction (BHJ) polymer solar cell (PSC) can improve harvesting properties, phase separation in the active layer and PSC performance.
In situgrowth and activation of an amorphous MoSxcatalyst on Co-containing metal–organic framework nanosheets for highly efficient dye-sensitized H2evolution
Authors: Liu Xiangyu , Min Shixiong , Xue Yuan , Tian Lei , Lei Yonggang , Wang Fang
Published: February 2019

In situgrown amorphous MoSxon Co-containing MOF nanosheets could efficiently catalyze visible light H2evolution in an ErB-sensitized system.
Optimized synthesis of Zr(iv) metal organic frameworks (MOFs-808) for efficient hydrogen storage
Authors: Xu Jiong , Liu Jin , Li Zhen , Wang Xianbiao , Xu Yongfei , Chen Saisai , Wang Zhuo
Published: February 2019

The optimized MOF-808 exhibited relatively high chemical stability and excellent hydrogen storage properties at different temperatures.
Phosphatase-mimicking activity of a unique penta-nuclear zinc(ii) complex with a reduced Schiff base ligand: assessment of its ability to sense nitroaromatics
Authors: Karmakar Mainak , Basak Tanmoy , Chattopadhyay Shouvik
Published: February 2019

A penta-nuclear zinc(ii) complex has been synthesized and characterized. The complex has shown good phosphatase-mimicking activity, which has been evaluated spectrophotometrically. The complex also behaves as a sensor for the detection of nitroaromatics via turn-off fluorescence response.
Highly oriented GeSe thin film: self-assembly growth via the sandwiching post-annealing treatment and its solar cell performance
Authors: Chen Binwen , Ruan Yurong , Li Jianmin , Wang Weihuang , Liu Xinlian , Cai Huiling , Yao Liquan , Zhang Jian-Min , Chen Shuiyuan , Chen Guilin
Published: February 2019

A highly (100) oriented GeSe thin film was deposited by evaporation and novel sandwiching post-annealing, achieving a device with a high VOC.
Spatiotemporal control over the host–guest characteristics of a stimulus-triggerable trifunctional polymer assembly
Authors: Khomein Piyachai , Dutta Kingshuk , Gnanasekaran Karthikeyan , Gianneschi Nathan C. , Thayumanavan S.
Published: February 2019

The positional effect of stimuli-responsive units in tri-component copolymer vesicles is studied to explore variations in the host–guest properties of the assembly.
Catalysts for gasification: a review
Authors: Arnold R. A. , Hill J. M.
Published: February 2019

Gasification catalysts, either intrinsic to the feed or added, are discussed as to their advantages, disadvantages, and interactions.
Fabrication of surface renewable carbon microelectrode arrays and their application in heavy metal ion sensing
Authors: Jin Yan , Mao Minmin , Ge Yuqing , Huang Shanluo , Ju Jiaqi , Jin Qinghui , Offenhäusser Andreas , Zhao Jianlong
Published: February 2019

In this paper, surface renewable carbon microelectrode arrays (MEAs) were developed using microfabrication technology and were successfully applied in heavy metal ion sensing.
Conformation-induced separation of 3-chloropropene from 1-chloropropane through nanoporous monolayer graphenes
Authors: Xu Yinxiang , Zhang Yujia , Wang Steven , Xu Junbo , Yang Chao
Published: February 2019

Conformation-induced separation shows that C3H5 twisting to the pore preferred cis-conformation with a lower energy penalty than C3H7 can cross the nanopore.
Tailored high cycling performance in a solid polymer electrolyte with perovskite-type Li0.33La0.557TiO3 nanofibers for all-solid-state lithium ion batteries
Authors: He Kang-Qiang , Zha Jun-Wei , Du Peng , Cheng Samson Ho-Sum , Liu Chen , Dang Zhi-Min , Li Robert K. Y.
Published: February 2019

Solid polymer electrolytes (SPEs) have drawn considerable attention owing to their reliable safety performance, electrochemical stability and exceptional flexibility.
Substituent dependence on the spin crossover behaviour of mononuclear Fe(ii) complexes with asymmetric tridentate ligands
Authors: Saiki Ryo , Miyamoto Haruka , Sagayama Hajime , Kumai Reiji , Newton Graham N. , Shiga Takuya , Oshio Hiroki
Published: February 2019

Three mononuclear iron(ii) complexes with novel asymmetric tridentate ligands were synthesized and their structures and magnetic properties were studied. The ligand substituents were found to affect the supramolecular packing and spin-crossover properties of the complexes.
Thermochromism of bromotellurates(iv): experimental insights
Authors: Shayapov Vladimir R. , Usoltsev Andrey N. , Adonin Sergey A. , Sokolov Maxim N. , Samsonenko Denis G. , Fedin Vladimir P.
Published: February 2019

Thermally induced changes in optical properties (thermochromism) in an extended series of 16 bromotellurate(iv) complexes were investigated; regularities valid for this class of compounds were established.
Sand/carbon composites as low-cost lithium storage materials with superior electrochemical performance
Authors: Wang Yangfeng , Zhou Luoting , Liang Chu , Zhang Jun , Huang Hui , Gan Yongping , Xia Yang , Tao Xinyong , Zhang Wenkui
Published: February 2019

This work has developed a facile method to prepare anode materials for LIBs from natural sand and low-cost polymers.
α,β-Unsaturated butenolides in an organocatalytic doubly annulative cascade for the preparation of 3,4-dihydrocoumarins
Authors: Kowalczyk-Dworak Dorota , Albrecht Łukasz
Published: February 2019

An organocatalytic doubly annulative cascade utilizing α,β-unsaturated butenolides and imines (derived from salicyl aldehydes and α-amino-γ-lactones) as starting materials is described.
Correction: Transfection efficiencies of α-tocopherylated cationic gemini lipids with hydroxyethyl bearing headgroups under high serum conditions
Authors: Maiti Bappa , Kamra Mohini , Karande Anjali A. , Bhattacharya Santanu
Published: February 2019

Correction for ‘Transfection efficiencies of α-tocopherylated cationic gemini lipids with hydroxyethyl bearing headgroups under high serum conditions’ by Bappa Maiti et al., Org. Biomol. Chem., 2018, 16, 1983–1993.
Performing linear convergence for distributed constrained optimisation over time‐varying directed unbalanced networks
Authors: Lü Qingguo , Li Huaqing , Wang Zheng , Han Qi , Ge Wei
Published: February 2019

The problem of distributed constrained optimisation over a network of agents, where the goal is to cooperatively minimise the sum of all local convex objective functions is studied. Each agent in the network possesses only its private local convex objective function and is constrained to a coupling equality constraint and its local inequality constraint. Moreover, the authors particularly focus on the scenario where each agent is only allowed to interact with their in‐neighbours over a series of time‐varying directed unbalanced networks. To collectively address the optimisation problem, a novel distributed primal‐dual push‐DIGing (integrated push‐sum strategy with distributed inexact gradient tracking method) algorithm (termed as DPD‐PD) in which agents employ uncoordinated step‐sizes is proposed. Unlike other methods, DPD‐PD allows not only the mixing matrices are column‐stochastic, but also the step‐sizes are uncoordinated. An important feature of DPD‐PD is handling distributed constrained optimisation problems in the case of time‐varying directed unbalanced networks. When objective functions are strongly convex and smooth, the authors demonstrate that DPD‐PD converges linearly to the optimal solution given that the uncoordinated step‐sizes are smaller than an upper bound. Explicit convergence rate is also conducted. Preliminary results on some numerical experiments validate the theoretical findings.
Position‐heading quadrotor control using LPV techniques
Authors: Trapiello Carlos , Puig Vicenç , Morcego Bernardo
Published: February 2019

This work presents a solution to the position‐heading control problem of a small quadrotor. The main idea of this study is to exploit the advantages of the linear parameter varying (LPV) control approach together with a feedback linearisation approach for designing a cascade control structure without the need to perform simplifications with respect to the reference dynamic model used in the literature. The use of a LPV representation of the attitude subsystem allows to consider it as independent of the position one, allowing the use of a cascade control structure. For the inner attitude control loop, the proposed quasi‐LPV–linear‐quadratic regulator (LQR) controller and proportional–integral observer (PIO) are solved in an optimal manner by solving a set of linear matrix inequalities (LMIs). While for the outer position control loop, a feedback linearisation approach is developed before designing the corresponding controller and PIO also minimising the LQR problem by means of LMIs. Furthermore, another outer loop, interchangeable with the position one, such that controls the velocities in the body frame is proposed. This velocities controller is also solved in an optimal manner using a combination of feedback linearisation and LPV techniques. The proposed solutions are applied to an AscTec Hummingbird unmanned aerial vehicle in simulation.
Two‐voltage hierarchical model predictive control for a single‐phase cascaded H‐bridge rectifier
Authors: Qi Chen , Chen Xiyou , Su Lijuan , Lang Zhengying
Published: February 2019

The finite‐control‐set model predictive control (FCS‐MPC) method is promising for cascaded H‐bridge (CHB) rectifiers. However, three issues arise in the traditional FCS‐MPC method: heavy computational burden, low steady‐state performance, and time‐consuming tuning work of weighting factor. Although some modified FCS‐MPC methods have been proposed for CHB rectifiers, there is an open task to solve all aforementioned issues simultaneously. Here, a novel FCS‐MPC method has been proposed for a single‐phase CHB rectifier. In proposed method, the computational burden is reduced from exponential time to linear time. The steady‐state performance is improved by selecting an optimal combination of two output voltages along with their duty cycles. The weighting factor is eliminated by using a hierarchical control structure. The proposed method has been tested and evaluated against three existing FCS‐MPC methods on a single‐phase three‐cell CHB rectifier.
Emphasis on switch selection and its switching loss comparison for on‐board electric vehicle charger
Authors: Srivastava Manaswi , Tomar Pavan Singh , Verma Arun Kumar
Published: February 2019

A DC/DC converter plays a vital role in on‐board electric vehicle (EV) charger. Among the many converter topologies, the phase‐shifted full‐bridge DC/DC converter (PSFBDC) is widely used. For improved efficiency, PSFBDC is embedded with passive auxiliary networks resulting in several unique configurations for achieving soft‐switching in entire load range. The architecture of the chosen DC/DC converter configuration should comply with the society of automotive engineers (SAE) standards. Although, the conduction loss of the converter can be minimised by choosing a proper topology configuration and proper switching of the configuration, the selection of appropriate for PSFBDC plays an important role in enhancing the overall efficiency. An optimistic method for the selection of switch configuration satisfying the reduced power loss and cost‐effective aspects is presented. For demonstrating the proposed method, a 1 kW 100 kHz system with commercially available switches IRFP460, IXFN64N60P, and IPP65R045C7 is chosen and the obtained results are presented.
Cutoff periods of magnetoacoustic waves in the solar atmosphere
Authors: Kraśkiewicz J. , Murawski K. , Musielak Z. E.
Published: February 2019

We perform numerical simulations of magnetoacoustic waves (MAWs) in the solar atmosphere, which is gravitationally stratified and structured by either vertical or horizontal uniform magnetic fields. These waves are excited by a monochromatic driver that operates in the photosphere. We show that the gradients of the atmospheric parameters lead to filtering of the waves through the solar atmosphere and to variations of the dominant wave period with height. We use these variations to determine a local cutoff period, which shows a good agreement with the previously obtained analytical and numerical results in an isothermal solar atmosphere. In our numerical simulations, the propagation of MAWs in a more realistic model of the solar atmosphere is considered, and the obtained results demonstrate that the waves with periods higher than a local cutoff wave period are strongly reflected and become evanescent with height, while the waves with shorter wave periods are propagating, and may even reach the solar corona. Some of the evanescent waves may also tunnel and reach the atmospheric heights that would not be otherwise accessible to them. An important result of our study is excitation of chromospheric oscillations with periods equal to the period that is comparable to the observed solar chromospheric oscillations. Implications of our theoretical predictions are discussed.
The BEBOP radial-velocity survey for circumbinary planets
Authors: Martin David V. , Triaud Amaury H. M. J. , Udry Stéphane , Marmier Maxime , Maxted Pierre F. L. , Cameron Andrew Collier , Hellier Coel , Pepe Francesco , Pollacco Don , Ségransan Damien , West Richard
Published: February 2019

We introduce the BEBOP radial velocity survey for circumbinary planets. We initiated this survey using the CORALIE spectrograph on the SwissEulerTelescope at La Silla, Chile. An intensive four-year observation campaign commenced in 2013, targeting 47 single-lined eclipsing binaries drawn from the EBLM survey for low mass eclipsing binaries. Our specific use of binaries with faint M dwarf companions avoids spectral contamination, providing observing conditions akin to single stars. By combining new BEBOP observations with existing ones from the EBLM programme, we report on the results of 1519 radial velocity measurements over timespans as long as eight years. For the best targets we are sensitive to planets down to 0.1MJup, and our median sensitivity is 0.4MJup. In this initial survey we do not detect any planetary mass companions. Nonetheless, we present the first constraints on the abundance of circumbinary companions, as a function of mass and period. A comparison of our results toKepler’s detections indicates a dispersion of planetary orbital inclinations less than ~10°.