bluuebunny/crossref_metadata_2025 huggingface dataset:
High-Performance Hydrogen Sulfide Gas Sensors Based on Conjugated Polymer Nanocomposites
Authors: Rashmi H S , Vishnumurthy K A , Kusanur Raviraj
Published: May 2024

In this study, we present the synthesis of a conjugated polymer through the oxidative polymerization method and the fabrication of nanocomposite thin-film sensors tailored for the detection of hydrogen sulfide (H2S) gas. Nanocomposite sensors have exhibited outstanding sensitivity, especially in response to 5 ppm of H2S gas. These sensors consistently demonstrated remarkable selectivity for the target gas at a 5 ppm concentration compared to other tested gases. Notably, the response time for these sensors was rapid, with values consistently ≤ 1 second, and the recovery times were notably shorter than those of pure polymer sensors. The highest sensitivity, reaching 1.22, was achieved by the 15% conjugated polymer nanocomposite (PCF) sensor, showcasing exceptional response-recovery characteristics. Furthermore, we calculated the limit of detection for the pure polymer and PCF nanocomposite sensors to be 9.8 ppm and 5.1 ppm, respectively. Our sensors also exhibited excellent repeatability, with consistent performance over 5 cycles when exposed to 2.5 ppm of gas at room temperature. This enhanced response-recovery behavior can be attributed to an increased number of active sites on the sensor's surface, resulting in faster gas adsorption and desorption processes. Consequently, these findings hold promise for the development of highly efficient hydrogen sulfide gas sensors.
Exploring Stress-Induced Mechanisms in Acne Pathogenesis
Authors: Siddiqui Ifrah , Rais Ubaid , Tahir Mehak
Published: May 2024

Background: Acne vulgaris affects millions worldwide, with psychological stress emerging as a significant contributor to its development. Stress influences acne via hormonal fluctuations, inflammation, immune modulation, altered skin barrier function, and lifestyle changes. Understanding these mechanisms is crucial for developing effective management strategies. This study aims to elucidate the role of stress in acne pathogenesis to inform more targeted interventions.Methods: A comprehensive search encompassing databases such as PubMed, MEDLINE, Google Scholar, open access / subscription-based journals, was conducted to retrieve relevant articles for the investigation of key mechanisms through which stress impacts acne development and exacerbation. Articles were searched without any date restrictions. Utilizing the criteria delineated in the methodology section, studies were systematically reviewed to elucidate the relationship between psychological stress and acne development and exacerbation. This study adheres to relevant PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-Analyses).Results: Our investigation revealed multiple key mechanisms through which stress impacts acne development and exacerbation. Hormonal fluctuations, including increases in cortisol and androgens, stimulate sebaceous gland activity, leading to excess sebum production. Inflammation, triggered by stress-induced cytokine release, exacerbates acne lesions. Stress also impairs skin barrier function, alters immune responses, and influences lifestyle factors such as diet, sleep, and skincare habits, all of which contribute to acne severity. Additionally, neuropeptides, oxidative stress, insulin resistance, altered skin pH, vascular changes, and changes in the skin microbiome play significant roles in stress-induced acne pathogenesis. These findings highlight the varied nature of stress-acne interactions and underscore the importance of addressing both physiological and psychological factors in acne management strategies.Conclusion: Our investigation reveals stress's varied impact on acne through hormonal fluctuations, inflammation, barrier function impairment, immune modulation, behavioral factors, psychological distress, neuropeptides, oxidative stress, insulin resistance, altered skin pH, vascular changes, lifestyle habits, and skin microbiome alterations. Addressing these mechanisms underscores the need for holistic acne management strategies integrating stress reduction techniques with conventional treatments. Understanding stress-acne interplay emphasizes the importance of comprehensive approaches to improve acne outcomes, recognizing the bidirectional relationship between physiological and psychological factors in acne pathogenesis and exacerbation.
Assessment of Three Fast Growing Populus Deltoides Species in Various Soil Profiles Under Nursery Conditions
Authors: Saleem Aamir , Jamshed Zeeshan , Farooq Mohammad Umar , Khan Nosheen , Anwar Fawad
Published: May 2024

Populus plants arefast-growing plants that exhibit strong adaptability and a short rotation period. Poplar enhanced the carbon stock, which ultimately helps in combating climate change and sustaining livelihoods. Pakistan has a shortage of firewood and timber. Thus, hybrid fast-growing plants are the only way to balance wood demand and supply in the country. Therefore, the objective of the present study was to evaluate and compare the growth patterns and carbon stocks of three Populus deltoides varieties in three soil media under nursery conditions. To achieve the study goals, three fast-growing hybrid species of Populus deltoides, Italian Populus (euramerciana), clone A-Y48, and local Populus were used. Three healthy plants of mothers aged one to two years were selected from the field area of the Rangeland Research Institute (RRI), NARC. The cuttings were planted in 90 pots after being filled with three different media, and plant growth was recorded after seven days for the number of leaves, height, diameter, and number of irrigations applied to each pot. Three-month data were collected and analyzed by using an RCBD design. After the trial, all the plants were exhausted, and soil samples were taken from the pots and brought to the RRI laboratory for the estimation of total biomass and carbon stocks. It was concluded that Clone AY-48 achieved the highest height among all the Populus deltoides varieties and stored more carbon stock in comparison to Italian and local poplar varieties. Farmyard manure had a positive influence on the height of the different Populus deltoides varieties. Clone AY-48 and Italian poplar plants are more suitable for rapidgrowth.
A Comprehensive Examination of UV-VIS Spectrophotometric Methods in Pharmaceutical Analysis Between 2015-2023
Authors: Eneş Duygu , Daştan Kerem , Kaplan Ozan , Çelebier Mustafa , Dogan Aysegul
Published: May 2024

Background:

Quality control is a system of validated procedures in which many
samples, including active pharmaceutical ingredients and final products, are analyzed using
standard or validated analytical methods.

Method:

Analytical methods used in analyzing active pharmaceutical ingredients or final products
in the pharmaceutical industry can be methods registered in pharmacopeias and developed
by the company itself. For this reason, published papers related to pharmaceutical analysis attract
analysts and researchers' attention. In this study, pharmaceutical analysis and bioanalysis
studies carried out between 2015 and 2023 were examined using Google Scholar, and the recent
trends were determined for pharmaceutical analysis. Among the published papers performing
conventional analytical techniques for pharmaceutical analysis, those applying UV-VIS spectrophotometry
method were selected to predict a future perspective in this study. In addition to
the data obtained, the current situation of the pharmaceutical industry was considered to correlate
with the obtained data for pharmaceutical analysis.

Results:

The results were presented with comparative tables and summarizing graphs. Interpreting
the results allowed us to determine the trends that pharmaceutical analysis studies will lead
in the future. This study can be helpful for researchers working on pharmaceutical analysis in
both the industry and academia to predict future trends in pharmaceutical analysis. As a result of
the literature research covering the dates 2015-2023, 56% of UV-VIS Spectrophotometric
methods are used on pharmaceutical dosage forms, 27% are bulk, 16% are pure, 2% are biological
materials, and 0.4% are herbal. Made from materials. Of these studies, 28% were conducted
in the 200-240 nm range, 27% were conducted in the 240-300 nm range, and only 44% were
conducted at >300 nm. Interpreting the results allowed us to determine the trends that pharmaceutical
analysis studies will lead in the future.

Conclusion:

This study can be helpful for researchers working on pharmaceutical analysis in
both the industry and academy side to predict future trends for pharmaceutical analysis.
Recent Nanosolutions Based on Green Propolis Presenting Useful Medical
Applications
Authors: Policarpo Tonelli Fernanda Maria , Policarpo Tonelli Flávia Cristina , Lourenço Vitória de Oliveira , Pinto Geicielly da Costa
Published: May 2024

Nanotechnology has the potential to offer elegant solutions to problems experienced
in the medical field, such as poor drug delivery efficiency and microbial resistance. In this sense,
it is interesting to associate nanomaterials with substances that also offer desirable properties to
favor human health. Green propolis is an example of a material that contains some of these useful
substances. The phenolic acids present in this type of propolis have already been proven to
present, for example, antimicrobial, immunostimulant, and antioxidant activities. In this minireview,
recent nano solutions, presented through manuscripts have been recently published
based on green propolis, receive attention due to their useful properties in the medical field.
Limitations to the clinical use of nanomaterials and the future prospects are also addressed.
Behavioral anhedonia in Major Depressive Disorder (MDD)
Authors: Wardani Ida Ayu Kusuma , Lesmana Cokorda Bagus Jaya
Published: May 2024

Introduction: Depression is a major public health problem, with existing pharmacological and non-pharmacological treatments not equally effective in all patients. The complex etiology and pathogenesis of depression pose a challenge that requires different approach strategies to effectively alleviate this mental symptom. Anhedonia, or loss of interest and pleasure in commonly enjoyed activities, is one of the main diagnostic criteria for depressive disorders in the psychiatric diagnostic systems of the Diagnostic Statistical Manual (DSM) and International Statistical Classification of Diseases (ICD). Major depressive disorder indicates a depressive condition that does not solely rely on reports of sad mood but the presence of anhedonia behavior. The review of these studies aims to determine changes in anhedonia behavior in depressive disorders. Methods: This research review was prepared using the literature review method by collecting valid scientific literature, namely Google Scholar, PubMed and Scientific Direct. Discussion: Anhedonia behavior is related to several factors, including social interaction is the most complex and ambiguous human environment. Hence the existence of rules that are fraught with misunderstandings. It requires complex examination to determine exactly what the rewarding components of social interaction are.
Treatment of blunt thoracic trauma in a Level 1 Trauma Center
Authors: ÁdÁm Bence , Szentkereszty Zsolt , Szentkereszty Zoltán , Vass Kitti Katalin , Urbán Ferenc
Published: May 2024

Blunt chest trauma has a significant high morbidity and mortality rate. In general, the treatment is conservative; in the case of hemothorax, pneumothorax, and hemopneumothorax chest tube drainage is often required. Immediate surgery is indicated in massive bleeding, tracheal and oesophageal injuries, and pericardial tamponade. Elective surgery should be performed in the case of retained hematoma, unresolved pneumothorax and flail chest. The first prioritized procedure is video-assisted thoracoscopy. The aim of this study is to analyze the treatment options and therapeutic results in reviewing 8,108 patients afflicted with blunt thoracic trauma. In over a three-year period 7,853 patients’ data were analyzed. Altogether 1,624 (20.68%) patients suffered severe injuries, such as sternal or rib fracture(s), pleural or lung injuries. In this group, a simple rib fracture (1-3) was diagnosed in 1,466 (90.27%), unilateral serial rib fracture (≥4) in 84 (5.17%), bilateral rib fracture in 16 (0.99%) and flail chest in 47 (2.89%) patients. In 11 (0.68%) cases, only parenchymal injuries without rib fracture were found. Altogether, 190 (11.70%) patients were afflicted with pneumothorax, hemothorax, or both, and only 86 (45.26%) of these cases required chest tube drainage. One immediate thoracotomy was needed to staunch massive bleeding and elective video-assisted thoracoscopy was performed in 6 cases. Lung contusion was diagnosed in 57 (3.51%) patients. The most frequent complication was pneumonia with a rate of 0.19% (15 patients). Empyema (3 patients), unresolved pneumothorax (1 patient), and retained hematoma (4 patients) occurred in 0.04%, 0.01% and 0.05% of the cases, respectively. Altogether, 13 (0.17%) patients succumbed at a mean age of 63.54±21.92 years. Three of these cases (23.08%) experienced multiple trauma and 12 (92.31%) suffered from concomitant chronic diseases. Patients with blunt chest trauma rarely required immediate operation. Overall, in the case of unresolved pneumothorax and retained hematoma, surgery is indicated, in which these cases video-assisted thoracoscopy is the first and primary option.
Arthroscopic treatment of femoral trochlear notch fracture caused by intra-articular dislocation of the patella
Authors: Wiegand Norbert , Bűcs Gábor , Patczai Balázs
Published: May 2024

This case report presents a traumatic intra-articular patellar dislocation – associated intercondylar fracture of the distal femur – and the consequent arthroscope assisted reduction and percutaneous screw fixation. To the best of our knowledge, this is the first case in which the arthroscope assisted operative reduction and percutaneous screw fixation of the fracture fragment has been demonstrated. Our patient was a 55-year-old female who was treated by the aforementioned method which concluded with excellent results.
PERBAIKAN KUALITAS PEMBELAJARAN BERBASIS IT-CANVA DI SEKOLAH TK AL IKHLAS MALANG
Authors: Nurwati Tri , Dhofir Moch , Wijono  , Unggul Wibawa  , Teguh Utomo  , Rini Nur Hasanah  , Hadi Suyono
Published: May 2024

TK AL-IKHLAS mempunyai program kegiatan nyata dalam rangka pengelolahan dan peningkatan kualitas lembaga. Rencana pengembangan TK AL-IKHLAS disusun dengan harapan program kegiatan lebih terencana dan terarah sesuai tujuan yang diharapkan, serta sesuai dengan manajemen sekolah. Salah satu hal yang dapat dilakukan adalah perbaikan manajemen sekolah melalui penggunaan aplikasi computer CANVA agar visi, misi, tujuan dan sasaran pendidikan pada TK Al Ikhlas Vila Gunung Buring dapat dicapai. Metode yang digunakan dalam pelaksanaan kegiatan pengabdian kepada masyarakat ini mencakup difusi ipteks yang dilanjutkan dengan penyuluhan/pelatihan.
Penentuan Batas Administrasi Desa Bangelan, Kecamatan Wonosari, Kabupaten Malang
Authors: Hasyim Abdul Wahid , Setyono Deni Agus , Sasongko Wisnu , Handoko Dwi , Anindya Salsabila , Raspati Gumiwang
Published: May 2024

Pengabdian Kepada Masyarakat dengan judul kegiatan ”Penentuan Batas Administrasi Desa Bangelan” bertujuan untuk memetakan batas-batas dari wilayah administrasi Desa Bangelan pada skala detail hingga tingkat RW. Adanya pemetaan tersebut diharapkan dapat bermanfaat sebagai sarana yang mendukung dalam pelaksanaan pembangunan desa, diantaranya terciptanya infografis skala detail, kondisi tertib administrasi, dasar dalam pengambilan kebijakan, dan peningkatan kualitas pelayanan publik. Metode yang digunakan dalam kegiatan ini adalah Participatory Rural Apprisial (PRA) dengan melakukan Focus Group Discussion (FGD) antara tim dan pihak desa. Kegiatan penentuan batas administrasi Desa Bangelan ini menghasilkan enam peta citra yang terdiri dari satu peta citra Desa Bangelan, empat peta citra Dusun, dan satu peta citra kawasan perkebunan. Peta citra bangelan yang sudah dibuat dapat dipublikasikan dan dipajang sebagai informasi baik bagi pemerintah maupun masyarakat. Selanjutnya dapat dilakukan sosialisasi kepada masyarakat terkait batas Desa Bangelan agar masyarakat paham terkait pentingnya batas desa.
A Tendency to Forget: Reparar (n)o Passado Para Resistir ao Esquecimento. Entrevista com a Artista Ângela Ferreira
Authors: Almeida Viviane , Macedo Lurdes , Zanete Renata Flaiban
Published: May 2024

No âmbito da “Escola de Verão em Comunicação e Cultura para o Desenvolvimento”, realizada na Universidade do Minho, em 2020, as investigadoras que conduziram esta entrevista trabalharam no projeto Cultures, Past & Present (2018–2022), mais concretamente no eixo que buscava compreender a história, a memória e as narrativas associadas aos museus de etnologia em Portugal e em Moçambique. O papel pioneiro de Margot Dias na introdução do filme etnográfico, nos estudos conduzidos junto aos macondes de Moçambique, emergiu naturalmente como um aspeto central da investigação, associado ao papel determinante de Jorge Dias na criação do Museu de Etnologia em Lisboa. Com o avanço da pesquisa, foi possível identificar duas investigadoras e artistas com obra significativa sobre as missões etnográficas do casal Dias, com ênfase no papel assumido por Margot, ainda que com abordagens bastante distintas: a antropóloga e cineasta Catarina Alves Costa, professora da Faculdade de Ciências Sociais e Humanas da Universidade Nova de Lisboa, e a artista plástica Ângela Ferreira, professora da Faculdade de Belas Artes da Universidade de Lisboa. O estudo exploratório sobre o percurso artístico de Ângela Ferreira logo evidenciou a necessidade de se chegar à fala com esta criadora. Foi neste contexto que se realizou a entrevista aqui publicada, a qual decorreu em dois momentos, a 12 e a 19 de novembro de 2020, mas que conserva a atualidade dos temas e das questões abordados. Aliás, estes temas e questões estão na ordem do dia, se tomarmos em consideração o recente impulso dado ao debate sobre reparações históricas, em Portugal, após o Presidente da República, Marcelo Rebelo de Sousa, se ter mostrado favorável a tais reparações às ex-colónias, durante um encontro com jornalistas estrangeiros a 23 de abril de 2024.
Linguistic landscape and power representation at gas stations
Authors: Wahyuni Sri , Kurniati Ai , Susilawati Dyah
Published: May 2024

Gas stations are hazardous, highly flammable public places. Thus, signs containing prohibitions, warnings, information, and road directions are needed to prevent catastrophes. This study aims to identify the linguistic system of the signs and describe the representation of power through the signs. The research site is gas stations in Semarang. This study uses observation methods in data collection by documenting, sorting, and classifying data using a national language, region, foreign, or both based on the linguistic system. Spolsky and Cooper's (1991) taxonomy of signs is used to classify the data. The categories are then examined further to reveal the embedded power relations. The results show that the linguistic landscape at the gas stations uses a monolingual system, Indonesian. This system demonstrates the gas station authorities' concern about prioritizing the state language in public spaces. Suggestions embedded in the signs do not explicitly represent power relations. However, they represent power by removing the subjects and objects on these signs. Texts of prohibitions and warnings should be created by involving more people so that the texts on the gas station LL can be more user-friendly.
Identification of Mora in Sokuon, Tan’on, and Chouon by Japanese language learners in Indonesia
Authors: Febriyanti Rike , Febri Camelia Vonita , Sudiargo Ary
Published: May 2024

Japanese is regarded as mora-timed, while Indonesian is syllable-timed because it provides equal weight and time for all syllables. Indonesian learners are struggling in differentiating one mora and two moras, and single consonant and double consonants. This study investigated Indonesian respondents’ ability to identify double consonants (sokuon), short vowels (tan’on) dan long vowels (chouon). 62 Indonesian respondents were involved as they were asked to listen carefully to a set of sounds containing the three distinctive sounds once and to write the sentence they heard. The result showed that 18% of 62 respondents fail to identify the short vowel (tan’on) because they omit certain sounds, change the word form inaccurately and put words in the inaccurate position when they write the sentence. In identifying double consonants (sokuon), 11% of 62 respondents failed because they inaccurately changed the word form when writing the sentence. In identifying long vowels (chouon), only 6% of 62 respondents failed because they added unnecessary sounds and changed the word form inaccurately. In conclusion, although Japanese and Indonesian languages are different in their rhythm classes, Indonesian learners’ ability to identify the distinctive sounds of the Japanese language is relatively high although listening to the material more than once.
Analysing the acoustic evidence of consonant productions among students at the university level
Authors: Nur'Aini Siti
Published: May 2024

Learners of English as a second language (L2) whose first language (L1) is Indonesian tend to struggle to produce aspirated consonants. This study investigates whether the difficulties came from the interference of the L1 for the production of these sounds: [k], [b], [d], [g] in the final positions, and [p] and [t] in the stressed syllable. This study involved two cohorts of English department university students with different levels of fluency in L2 speech production. The L2 learners were asked to pronounce 25 words from a textbook previously used to teach them. The L2 learners were exposed to a British English-speaking speech model, which became a benchmark for the L2 learners’ pronunciation by asking them to imitate the pronunciation. Annotation of data was conducted twice by a second annotator to ensure the objectivity of the scores given to the L2 learners which was analised using paired sample t-test. Findings suggest that the sounds with the lowest success rate of production were [p] in the stressed syllable, [k], and [g] in the final position. The production was unsuccessful because the L2 learners did not have phonological awareness of how the L2 consonant sounds were produced near-natively and were affected by their L1. The lack of awareness led to the failure to produce [p], [k], and [g] sounds because these sounds did not exist in their L1 and interference of the L1 was embed to the L2 speech production. The format analysis results using PRAAT indicate that there is an improvement in the participants’ pronunciation after exposure to the native speaker’s speech sound. The implication of this research is paramount for L2 learners and lecturers in highlighting the importance of targeted instruction and intervention to address the challenges in speech production. Contrasting the phonetic features of L1 and L2 sounds helped the learners to defer interference in their L2 speech production. This study encourages continuous assessment of L2 learners to ensure that they maintain the consistency of speech production to sound near-native.
Women’s empowerment: Staging power resistance in Oshin (2013)
Authors: Tisnawijaya Christy , Kurniati Geni
Published: May 2024

Fictional movies captivated the audience in many ways through their stories and audio-visual. The stories of fictional movies often reflect what happens to our society, and we savor the purification of the hero’s tragic flaw. One of which is power relations between males and females. This study explores women’s empowerment in Oshin the movie (2013). The narrative is about a seven-year-old girl called Oshin, who is made to work as a maid by her father due to the family’s poverty. At first, she is against her father’s idea of being separated from her family. She struggles to become a maid until she is accused of stealing and runs away. By watching her mother’s efforts as the household pillar, she finally realizes the importance of being an independent female. The movie shows power relations issues regarding filial duty and social stratification. Yet, with the help of Foucault’s theory of The Subject and Power (1982), power resistance is a more eloquent outcome to discuss. Thus, this study proposes the stages of power resistance and how the protagonist declares her resilience through traditional gender roles. Moreover, this study uses an interpretative method by scrutinizing each scene that shows power resistance; the discussion reveals that Oshin participates in staging power resistance for women’s economic empowerment, which subsequently contributes to her family’s economic development. This study concludes that financial independence and women’s empowerment are inextricably linked.
Ain’t no man: Female masculinity in Android game Legend of the PHOENIX
Authors: Adelia Silvy , Dirgantari Alfi , Hirano Shun , Wedawati Mamik , Ridha Firly , Koiri Much
Published: May 2024

This study performs content analysis on an Android game titled Legend of the Phoenix. Legend of the Phoenix, commonly known as LoP, is an otome (girl) game released by Modo Game in 2020. Like most otome games, Legend of the Phoenix revolves around the journey of a young woman who is given a second chance at life after her first ends tragically. The player takes the role of this young woman and has to complete various missions and storylines in order to complete the game. This study aims to find messages about gender presented in the game by analyzing its visual and narrative content. It focuses on identifying female masculinity in the special recruitment group of Female General or Heroine. The game characters being analyzed are the four Generals in Legend of the Phoenix—Hua Mulan, Mu Guiying, Liang Hongyu, and Qin Liangyu. They are examined in terms of role, abilities, and appearance and their relation to the concept of female masculinity introduced by Halberstam. The result shows that the Female General belongs to Femme Pretender type. It means that the characters of Hua Mulan, Mu Guiying, Liang Hongyu, and Qin Liangyu possess masculine traits (role and abilities) while also keeping their female appearance (physical and outfit).
Signs of nature in Bediuzzaman Said Nursi: A significant contribution to Islamic semiotics
Authors: Khalawi Hasan , Zarkasyi Hamid Fahmy , Rahardjo Mudjia
Published: May 2024

In the life circle, humans always produce, receive, and search for the meaning of signs. The meanings have ultimate value concerning Islamic worldview which then determines human salvation. Therefore, these issues are very important to research. The researchers worked in a deductive-inductive approach: a quasi-qualitative method characterized by the use of theories to be reconstructed after critical dialogues aimed at revealing the meanings of the natural signs based on an Islamic worldview and proposing a model of the Islamic theory of sign. The subject of this research is the books of Risale-i Nur as the representation of the Islamic worldview. Further, the techniques of the data collection are (1) preparing the domain (2) constituting the taxonomy of the data; (3) note-taking in the text of the Risale-i Nur. Furthermore, the latent content analysis was employed. The researchers categorized qualitative textual data into clusters of similar entities, or conceptual categories, to identify consistent patterns and relationships between themes. Finally, the researchers concluded that the meanings of the natural signs in the Risale-i Nur are the manifestation of the perfection of God’s Names. Moreover, the significant contribution of the Risale-i Nur to Islamic semiotics is revealed and proposed.
Intersectional identity of 13th-century Javanese women in the novel “Tutur Dedes”
Authors: Budiyanto Dwi , Kusmarwanti Kusmarwanti , Liliani Else , Sayuti Suminto A.
Published: May 2024

Within thirteenth-century Javanese tradition in Southeast Asia, women are frequently marginalized. Women who had significant influence were often omitted from historical records, such as Ken Dedes. Her tale is exclusively documented in the book of Pararaton. Dedes is seen as a significant woman who bore the ruling dynasty in Java. Modern Indonesian literature depict Dedes in different ways, offering varied interpretations of her character. This study seeks to analyze the intersectional identity of Ken Dedes in the novel Tutur Dedes: Doa Kutukan by Amalia Yunus (2022) because of the intricate nature of her identity. The data consist of narrative elements such as tale sequences, characters, settings, themes, and other literary devices sourced from data repositories relevant to the research issue. The data were collected using reading and note-taking methods. Additionally, it was qualitatively analyzed via the lens of Kimberle Crenshaw's (1989) intersectionality approach. The results indicate that Dedes is shaped by various intersecting identities: education for an educated identity, biological physique for beauty and sexuality, high social status for respectability and knowledge access, religion for personal integrity, gender for the role of a mother, and political position for influence and network power. Each component category interacts to shape, reinforce, and internalize Dedes' identity and self as an educated woman in the thirteenth century, who wields significant influence and can overcome the oppression she faces. This study emphasises the importance of viewing women's identities as a cohesive whole rather than in fragmented elements. Javanese women were well educated and engaged in many facets of society in the thirteenth century.
Biotechnology Innovation in Do-It-Yourself (DIY) Gene Editing: A Call for a New Regulatory Framework
Authors: Stasi Alessandro , Thongpravati Onnida
Published: May 2024

The expansion of do-it-yourself (DIY) gene editing, facilitated by Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology, has catalyzed a significant shift in scientific research and biotechnology innovation. This movement is propelled by a community-driven approach that challenges the traditional confines of scientific exploration, allowing amateur scientists to perform sophisticated biological experiments. While this democratization fosters inclusivity and accelerates innovation, it simultaneously introduces significant biosecurity risks. The possibility of unregulated gene editing leading to the unintentional creation of harmful organisms or the deliberate engineering of pathogens underscores the need for a new regulatory framework. This paper explores the implications of DIY biology within the context of public health, environmental safety, and biosecurity, highlighting the urgency for adaptive policies that balance scientific freedom with security. It proposes integrating community-driven regulatory practices with formal oversight mechanisms by examining biosecurity implications, ethical considerations, and the potential for misuse. Additionally, the role of decentralized autonomous organizations (DAOs) is explored as a novel approach to transforming governance within the domain of DIY gene editing, particularly in the context of CRISPR research.
Exploring User Experiences of the Mom2B mHealth Research App During the Perinatal Period: Qualitative Study
Authors: Bilal Ayesha-Mae , Pagoni Konstantina , Iliadis Stavros I , Papadopoulos Fotios C , Skalkidou Alkistis , Öster Caisa
Published: May 2024

Background

Perinatal depression affects a significant number of women during pregnancy and after birth, and early identification is imperative for timely interventions and improved prognosis. Mobile apps offer the potential to overcome barriers to health care provision and facilitate clinical research. However, little is known about users’ perceptions and acceptability of these apps, particularly digital phenotyping and ecological momentary assessment apps, a relatively novel category of apps and approach to data collection. Understanding user’s concerns and the challenges they experience using the app will facilitate adoption and continued engagement.

Objective

This qualitative study explores the experiences and attitudes of users of the Mom2B mobile health (mHealth) research app (Uppsala University) during the perinatal period. In particular, we aimed to determine the acceptability of the app and any concerns about providing data through a mobile app.

Methods

Semistructured focus group interviews were conducted digitally in Swedish with 13 groups and a total of 41 participants. Participants had been active users of the Mom2B app for at least 6 weeks and included pregnant and postpartum women, both with and without depression symptomatology apparent in their last screening test. Interviews were recorded, transcribed verbatim, translated to English, and evaluated using inductive thematic analysis.

Results

Four themes were elicited: acceptability of sharing data, motivators and incentives, barriers to task completion, and user experience. Participants also gave suggestions for the improvement of features and user experience.

Conclusions

The study findings suggest that app-based digital phenotyping is a feasible and acceptable method of conducting research and health care delivery among perinatal women. The Mom2B app was perceived as an efficient and practical tool that facilitates engagement in research as well as allows users to monitor their well-being and receive general and personalized information related to the perinatal period. However, this study also highlights the importance of trustworthiness, accessibility, and prompt technical issue resolution in the development of future research apps in cooperation with end users. The study contributes to the growing body of literature on the usability and acceptability of mobile apps for research and ecological momentary assessment and underscores the need for continued research in this area.
Long-term impedance dynamics of cochlear implant electrodes in children
Authors: Zaitsev A.V. , Berezniuk V.V. , Berezniuk I.V. , Chornokur O.A.
Published: May 2024

Background. Nowadays in Ukraine, there are about 3 thousand cochlear implant users, and their number is constantly increasing. The internal part of the implant remains in the cochlea throughout the patient’s life, but current data on the state of the electrodes in the long-term period are contradictory. The purpose was to study the impedance dynamics of cochlear implant electrodes during 5 years after surgery in children. Materials and methods. A retrospective study of 58 children with deafness after cochlear implantation was conducted. The changes in the interelectrode impedance and the relationship between them in the different parts of the electrode were evaluated and analyzed 1, 2, 3, and 5 years after the start of electrical stimulation. Results. At 1 year after the connection of the speech processor, an increase in the impedance was recorded in the basal part of the electrode (9–12 channels) relative to the medial and apical part of the cochlea. Over the next year, according to the electric field telemetry data, a significant (p < 0.05) downward trend was noted in the resistance in the basal part of the implant (9–12 electrodes). Within 2–5 years, a gradual decrease in the impedance in the medial and apical parts of the electrode occurred without statistically significant differences. In 29.3 % of cases, there was a tendency to a gradual increase in the impedance on 11–12 electrodes within 3–5 years after surgery. In another 8 patients (13.8 %), a critical increase in the impedance (> 15 kilohm) was detected on one of the contacts in the basal part of the electrode, which required their disconnection or correcting the settings of the speech processor. Conclusions. Regular monitoring of electrode impedance and electrical stimulation levels is recommended, especially during the first 2 years of implant use. This is necessary to improve the performance of the implant, to determine the most comfortable levels and thresholds of volume more accurately, which will improve the sound perception in children after cochlear implantation.
Role of interleukin-17 in juvenile idiopathic arthritis
Authors: Karimdzhanov I.A. , Madaminova M.Sh.
Published: May 2024

Joint diseases is a pressing problem of pediatrics. Juvenile idiopathic arthritis is a common chronic systemic inflammatory disease of the joints in children; its etiological factors remain completely unknown. The disease can affect children of any age and is characterized by a long progressive course, leading to the development of contractures and functional failure, and thereby disability. According to the authors of the article, the content of the interleukin-17 in the blood serum of children with juvenile idiopathic arthritis depends on the duration of the disease, as well as its severity.
Intellectual functionality of speech in children of older preschool age with logopathology
Authors: Bielova O.B.
Published: May 2024

Background. The purpose of this study is to identify the current state of intellectual functioning, which affects the speech readiness to study at school, of older preschool children with logopathology. The study included 607 older preschool children (5–6 years old), 250 with normotypical psychophysical development and 357 with speech disorders (dyslalia, stuttering, rhinolalia, dysarthria). Materials and methods. To evaluate the intellectual functioning of older preschool children with logopathology, methods were developed aimed at studying visual-motor coordination, auditory-verbal memory, verbal-spatial representation, verbal-logical thinking, verbal attention. Results. The results of the experimental study give a clear idea that there are significant differences in the formation of intellectual functionality between children with logopathology and those with normotypical psychophysical development. Older preschool children with speech disorders had low ability to copy graphic images, violations of independent control and planning their own activities, problems with the consistent reproduction of words, the volume of memorization, the strength of retention of stimuli, the speed and accuracy of reproduction of speech information, the difficulties understanding spatial relations in the addressed and own speech; verbal and logical skills are formed heterogeneously. Some preschoolers with logopatho­logy can classify objects by features, generalize them, understand the figurative meaning of words and the content of texts. Others experience certain difficulties and make many mistakes; their verbal attention is not sufficiently developed, which prevents children from perceiving educational material. Conclusions. Accordingly, low indicators of visual-motor coordination, auditory-verbal memory, verbal-spatial representation, verbal-logical thinking, verbal attention in older preschool children with speech disorders indicate insufficiently formed intellectual functionality. This will affect their speaking readiness and learning the curriculum at school.
Markers associated with the development of osteoporosis in children with juvenile idiopathic arthritis
Authors: Makoviichuk O.A.
Published: May 2024

Background. The purpose of the study was to investigate the association between bone mineralization le­vel in children with juvenile idiopathic arthritis (JIA) and various exogenous and endogenous factors. Materials and ­me­thods. The study group consisted of 162 children diagnosed with JIA. Medical history, clinical features, and treatment of JIA were studied. Disease activity was evaluated using the Juvenile Arthritis Disease Activity Score (JADAS-27), health status — with the Childhood Health Assessment Questionnaire (CHAQ). Complete blood count with erythrocyte sedimentation rate, biochemical analysis (C-reactive protein, total and ionized calcium) were performed, and instrumental methods (ultrasound densitometry, X-ray and ultrasound examination of joints) were used. Serum levels of osteocalcin, 25-hydroxyvitamin D (25(OH)D), and parathyroid hormone were evaluated using an enzyme-linked immunosorbent assay on an ER500 analyzer (Sinnowa, China). Results. According to our study, osteoporosis was observed in 19 patients (11 girls and 8 boys) out of 162 children with JIA, accounting for 11.7 %. It was significantly more frequent in patients with polyarthritis (73.7 %) compared to those with oligoarthritis (26.3 %) (p < 0.05). Conclusions. Osteoporosis can develop in children with JIA who do not receive systemic glucocorticoid therapy. The main markers associated with osteoporosis in children with JIA include non-infectious disease onset trigger, cervical joint involvement at disease onset, involvement of more than 3 joint groups at onset, gait disturbances, high JADAS-27 and CHAQ scores, signs of systemic inflammatory process, including elevated erythrocyte sedimentation rate.
Modern approaches to the training of pediatricians and assessment of their professional competences: domestic and American experience
Authors: Beketova H.V. , Volosovets O.P. , Horiacheva I.P. , Soldatova O.V. , Saltanova S.D.
Published: May 2024

In the article, issues related to the effective training of students/pediatricians and assessment of their competencies are discussed, taking into account the specifics of pediatric care in modern conditions. Nowadays, pediatricians are using a number of innovative technologies and provide daily assistance to a larger number of patients than before, with much less time spent on professional communication. To a certain extent, this reduces the desire of pediatricians to take care of children, because under such conditions, the art of communicating with a patient and his fa­mily members is lost. The article provides recommendations on the experience of American educational institutions regarding the effective elimination of communication problems between students/ pediatric residents and a patient, members of his family, and colleagues. It describes methods that help learn the principles of cultural and effective professional communication in order to improve understanding of the psychology of a child and his family members in the context of the family medicine. Further, information is provided regarding the key approaches to the formation of the main components of professionalism in pediatric practice at the undergraduate and postgraduate stages of the training of pediatricians, collegiality, resolving issues of conflict of interests in the context of cooperation with representatives of the pharmaceutical industry.
A Study of the Condition of Dalit in Contemporary Bangladesh
Authors: Gong Xvyue
Published: May 2024

Dalit are one of the important minorities in Bangladesh and have a significant impact on community relations within the country. Historically, they have suffered from a long history of unequal social discrimination. In order to escape stigmatization and improve their social status, Dalit in Bangladesh have been engaged in a series of human rights struggles in recent times. However, Dalit in Bangladesh continue to face unfair experiences to this day. Based on the existing literature, this paper presents the current situation of Dalit in Bangladesh and the initiatives taken by various sections of the society to improve the situation of Dalit.
Effects of Social Media on Branding ——The Rise of Creative Advertising Marketing
Authors: Li Anyi
Published: May 2024

In the Web2.0 era, social media has developed into the most compelling area in the global media industry and brought online users a fresher experience and more creative network communication application models. Both its social impact and economic development have become the new engine and growth point of the media industry. More and more brands and companies put their advertising budgets on social media advertising, because social media advertising is not only affordable but also able to accurately target the consumer group. The Internet word of mouth formed by social media is reshaping the relationship between brands and consumers. At the same time, the way audiences receive and disseminate information has undergone tremendous changes, and advertising creative communication is also facing huge challenges. This article will analyze the development process and trends of social media from the perspective of its core technology and communication characteristics, and then explore the social-psychological impact and cultural value of social media brought to brand communication.
Research on Copyright Recognition of Content Generated by Artificial Intelligence
Authors: Gao Jinyang
Published: May 2024

With the rapid development of artificial intelligence technology, artificial intelligence has developed into "expressive artificial intelligence", artificial intelligence-generated content (AIGC) is more and more widely used in various fields. However, there are still some disputes and confusion about the copyright ownership of these machine-generated content. This paper first introduces the basic concepts and characteristics of artificial intelligence-generated content under the current background. Secondly, this paper discusses the positioning of AIGC in the copyright law and the difficulties in protecting the rights and interests through the different views and legislative practices on the copyright recognition of artificial intelligent-generated content in the world. Finally, in view of the current disputes, such as "creative requirements" and "human participation", this paper puts forward the possible ways to solve this problem in the future, including improving the copyright law to clarify the right ownership and responsibility of AIGC, learning from foreign experience, and establishing the copyright ownership system of AIGC, etc., which provides a useful reference for the formulation and practice of relevant laws and regulations.
INNOVATORINNEN. Begleitforschung des Programms 2022 - 2023
Authors: Régent Verena , Ecker Brigitte
Published: May 2024

Bei dieser Studie handelt es sich um die Begleitforschung des im Jahr 2022 gestarteten INNOVATORINNEN-Programms. Die Begleitforschung umfasste zwei ganze Leadership-Durchgänge (Februar bis Dezember 2022 und Februar bis Dezember 2023) im Rahmen von „Modul 1“, sowie den Aufbau des INNOVATORINNEN Clubs (ab Herbst 2022) im Rahmen von „Modul 2“1. Zentrale Erkenntnisse *) Der Fokus auf einer individuellen inhaltlichen Gestaltungsmission machte das Leadership-Programm für die Zielgruppe besonders attraktiv und unterscheidet es von klassischen Frauenförderungsprogrammen. *) Die Gestaltungsmissionen konnten durch die Leadership-Durchgänge mit mehr Klarheit, Selbstbewusstsein, Motivation und Know-How konkretisiert und weiterentwickelt werden. *) Das Leadership-Programm wirkt dadurch auch auf den Ausbau von Innovationskompetenzen, Kontakten, der Umsetzung der individuellen Vorhaben und Initiierung (gemeinsamer) Projekte. *) Bisher ungedeckte Kompetenzbedarfe zeigten sich ausschließlich im Bereich der Risikobereitschaft – alle anderen abgefragten Kompetenzen wurden als gut abgedeckt befunden. *) Die Heterogenität der Teilnehmerinnen in den INNOVATORINNEN Leadership-Durchgängen stellte aus deren Sicht einen großen Mehrwert dar. *) Die Vernetzung mit der Peer Group und das herausragende Engagement des Programmmanagements bieten ein wichtiges Alleinstellungsmerkmal der Leadership-Durchgänge. *) Auch die Formate des INNOVATORINNEN Clubs wurden in jeder Hinsicht überwiegend positiv bewertet; als künftige Schwerpunkte wurden Vernetzungs- und Projektplattformen sowie Mentoring-Aktivitäten angeregt. *) Mit Blick auf die Unterstützung vonseiten der FFG wurde der Wunsch nach themenoffenen, interdisziplinären und nicht-klassischen F&I-Fördermöglichkeiten zum Ausdruck gebracht.