bluuebunny/crossref_metadata_2025 huggingface dataset:
Observations on the language of the newly discovered Phrygian inscription from Gordion (G-12)
Authors: Oreshko Rostyslav
Published: January 2024

The article presents a detailed philological and linguistic commentary on the Phrygian (Mysian) inscription discovered in 2021 at Gordion (§§ 1-18). The final part (§ 19) offers observations on the ethnolinguistic and sociolinguistic background of the text which can be associated with the region of Pergamon in Mysia.
Voyelles nasales et voyelles nasalisées en lycien
Authors: Patri Sylvain
Published: January 2024

Resume

Les realisations des voyelles nasales ayant un statut de phoneme imposent certaines proprietes a leur entourage tout en connaissant des variations de leur degre de hauteur; par contraste, les voyelles nasalisees recoivent leur proprietes de leur entourage ne varient pas selon la hauteur. L’emergence de voyelles distinctivement nasales en lycien resulte d’un conditionnement pour partie segmental (co-articulation), pour partie syllabique (elimination des codas).
The Italian Bella Figura – a challenge for politeness theories
Authors: Held Gudrun
Published: January 2024

This paper examines the Italian folk concept of bella figura in the framework of politeness-theories and the various binary conceptions it provides for explaining the nature of human communication. BF is a culture-specific understanding of self-projection in everyday discourse: It is both, a cognitive concept concerning the “beautiful” embodiment of self, and a performative concept concerning the active “figuring out” of a bella figura in order to avoid its contrary, the brutta figura. Thus, the figura-concept represents a pragmatic principle for acting in line with socially accepted norms setting out a reference frame for judging social endeavours according to a culture-inherent value system. Accordingly, affinities can be assumed between the figura-concept and the sociopragmatic core notions ‘face’ and ‘politeness’. A comparison of the figura-concept with the respective first- and second-order conceptions of the two, reflects a cultural version of ‘impression management’ conceiving an image of self which coincides with Goffman’s, but not at all with Brown and Levinson’s face-concept. This makes it difficult to identify figura in relation to politeness. Connections and disconnections are discussed alongside the paradigmatic binary scales and the positive/negative value-attributes. Finally, the findings are verified by comparing the use of the respective expressions as evaluation tools.
Battista, Ludovico (2021). Hans Blumenberg e l’autodistruzione del cristianesimo.
La genesi del suo pensiero: da Agostino a Nietzsche. Viella, Roma.
Authors: López Forjas Manuel
Published: January 2024

El estudio que el profesor Battista ha publicado sobre Hans Blumenberg constituye
una novedad muy importante en los estudios de la filosofía contemporánea, tanto por su
sólida cimentación bibliográfica como por sus apreciaciones críticas que permiten trazar
un hilo conductor en la construcción del pensamiento del filósofo alemán.
Research on Human Resource Allocation Algorithm for Application Integration Feature Selection in the Internet of Things Environment
Authors: Yan Zhang
Published: January 2024

In the context of the Internet of Things, the existing human resource optimization allocation methods have problems such as time-consuming resource allocation, improper allocation, improper matching between tasks and resources, and unsatisfactory human resources. This paper proposes a new human resource allocation method based on the multi-objective method, that is, the use of comprehensive feature selection for resource allocation. The method first extracts human resource features to establish a database, then completes feature selection based on the comprehensive feature selection method, establishes the human resource allocation model, and allocates resources according to various factors and resource characteristics. Finally, the genetic algorithm is used to solve the human resource allocation model to achieve the optimal allocation of human resources. The experimental results show that the proposed method takes a shorter time to allocate human resources and a shorter time to execute tasks after the allocation is completed, which verifies the high scheduling efficiency and effectiveness of the proposed method.
“La isla en peso”. Espacio literario e intertextualidad en Wide Sargasso Sea, de Jean Rhys
Authors: Goenaga Conde Beatriz M.
Published: January 2024

The main objective of this article is aimed at assessing the functions of intertextuality in the construction of the Caribbean insular space in Wide Sargasso Sea, by the Dominican writer Jean Rhys. For this reason, it was analyzed the intertextual relations between Jane Eyre, by Charlotte Bronte and Wide Sargasso Sea, by Jean Rhys with emphasis on the island as an explicitly presented literary space. As a result, it was found that the main function of intertextuality in this text responds to the Calibanesque and demystifying intention of dismantling the archetypes in which the image of the other has been erected in the discourse of power. Likewise, the present analysis has made it possible to reveal the richness of the connotation granted in Wide Sargasso Sea to the island and its added meanings. This network of meanings reinforces its Caribbean cultural identity.
La fotografía en un contexto de cambio para el Caribe hispano insular
Authors: Rodríguez Puerto Kirenia
Published: January 2024

After the Second World War, the Caribbean art experienced profound transformations in their creative practices and modes of cultural understanding. The complex social and political realities in the islands of the Hispanic Caribbean led to a turning point in regional processes, a transformation of the art field, and rethinking of peripheral discourses. from the demonstrations, the topics of interest and the role of the artist in society. Photography, and especially that coming from peripheral spaces in the international logic of art, contributed the most rebellious icons of the moment. The cultural symbols of a new voice, which responds to an emancipatory and decolonizing thought, is expressed in the construction of a visual discourse of ethical and libertarian paradigms. The most innovative language of the time appealed to a background photographic base due to the relationship between immediacy and pregnancy of the image, or the inherent reproducibility that fosters a more effective communicative function.
Standardizing Medication Reconciliation in a Pediatric Emergency Department
Authors: Sheth Sarika , Bialostozky Mario , Hollenbach Kathy , Heitzman Lindsay , O’Crump Deven , Mishra Seema , Langley Gregory , Santiago Kristen , Saleh Fareed , Billman Glenn , Bryl Amy
Published: January 2024

BACKGROUND

Medication errors are common during transitions of care, such as discharge from the emergency department (ED) or urgent care (UC). The Joint Commission has identified medication reconciliation as a key safety practice. Our aim was to increase the percentage of patients with completed medication reconciliation at discharge from our pediatric ED and 4 UCs from 25% to 75% in 12 months.

METHODS

Key stakeholders included ED and UC physicians and nurses, informatics, and quality management. The baseline process for medication reconciliation was mapped and modified to create a standard process for nurses and physicians. An Ishikawa diagram was created to assess potential failures. Electronic health record interventions included adapting an inpatient workflow and using a clinical decision support tool. Educational interventions included just-in-time training, physician education via division meeting presentations, video tutorials, and physician-specific and group feedback using funnel plots. The secondary process measure was the proportion of patients discharged from the ED and UCs with completed home medication nursing review. We used statistical process control to analyze changes in measures over time.

RESULTS

In the UCs, home medication nursing review increased from 91% to 98% and medication reconciliation increased from 35% to 82% within 4 months. In the ED, home medication nursing review increased from 2% to 83% within 8 months and medication reconciliation increased from 26% to 64% within 18 months.

CONCLUSIONS

We successfully increased the proportion of UC and ED discharged patients with completed medication reconciliation.
Asociación entre Glucemia Inestable, Tiempo de Estancia y Mortalidad de Pacientes en Estado Críticos: Estudio de Cohorte
Authors: Neto Letícia Marques da Silva , Brinati Lídia Miranda , Toledo Luana Vieira , Januario Carla de Fatima , Teixeira Andreza de Oliveira , Andrade João Vitor , Salgado Patrícia de Oliveira
Published: January 2024

Introducción: El control y la evaluación de los niveles glucémicos de pacientes en estado críticos es un desafío y una competencia del equipo de enfermería. Por lo que, determinar las consecuencias de esta durante la hospitalización es clave para evidenciar la importancia del oportuno manejo.
Objetivo: Determinar la asociación entre la glucemia inestable (hiperglucemia e hipoglucemia), el resultado de la hospitalización y la duración de la estancia de los pacientes en una unidad de cuidados intensivos.
Metodología: Estudio de cohorte prospectivo realizado con 62 pacientes a conveniencia en estado crítico entre marzo y julio de 2017. Se recogieron muestras diarias de sangre para medir la glucemia. Se evaluó la asociación de la glucemia inestable con la duración de la estancia y el resultado de la hospitalización mediante ji al cuadrado de Pearson. El valor de p<0.05 fue considerado significativo.
Resultados: De las 62 personas participantes, 50 % eran hombres y 50 % mujeres. La edad media fue de 63.3 años (±21.4 años). La incidencia de glucemia inestable fue del 45.2 % y se asoció con una mayor duración de la estancia en la UCI (p<0.001) y una progresión a la muerte como resultado de la hospitalización (p=0.03).
Conclusión: Entre quienes participaron, la glucemia inestable se asoció con una mayor duración de la estancia más prolongada y con progresión hacia la muerte, lo que refuerza la importancia de la actuación de enfermería para prevenir su aparición.
Sentimentos da Mulher Frente a Gestação de Alto Risco
Authors: Nunes Maria Brena Lopes , Oliveira Talita Jácome de , Silva Júnior José Antonio da , Nascimento Ellany Gurgel Cosme do
Published: January 2024

Introdução: A gestação configura-se como um acontecimento único e memorável para a vida de uma mulher. A gravidez de alto risco é uma experiência estressante em razão dos riscos a que estão submetidos a mãe e o bebê e devido às mudanças que afetam negativamente o seu equilíbrio emocional.
Objetivo: Identificar os sentimentos vivenciados pela gestante frente à gravidez de alto risco.
Método: Descritivo e exploratório com abordagem qualitativa, com amostra por conveniência composta por mulheres com gestação de alto risco, selecionadas de acordo com a disponibilidade do serviço de internamento, até a saturação das entrevistas. A coleta dos dados foi realizada em um período de dois meses através de entrevistas guiadas por um roteiro. Os dados foram analisados por meio da técnica de análise de conteúdo segundo Minayo.
Resultados: Fizeram parte 37 mulheres. Os resultados foram oeganizados nas categorias: Como se deu o diagnóstico de alto risco; Sentimentos ao descobrir que a gestação é/era de risco; Sentimentos em relação ao apoio familiar acerca da gestação de alto risco. Os sentimentos relatados pelas gestantes e puérperas que conviveram com a gravidez de alto risco, deixam evidentes os impactos que este evento traz não somente na saúde física sobretudo para a emocional, deixando as gestantes fragilizadas.
Conclusão: Assim, o estudo nos permitiu perceber que os sentimentos vivenciados nesse processo podem interfir na vida dessas mulheres, e de forma negativa. Mas, que apesar dessa situação, estas expressam sentimentos ambíguos, pois mesmo com o risco gestacional, muitas mostram-se felizes pela dádiva de ser mãe.
Demandas clínicas e intervenções de enfermagem em consultas gerontológicas
Authors: Muniz Vinícius de Oliveira , Pereira Leal Marcos Vinícius , Do Espírito Santo Fátima Helena , Chaves Pedreira Larissa , Reis de Sousa Anderson
Published: January 2024

Introdução: À medida que a população envelhece, a ascensão de fragilidades físicas, psicológicas, sociais e espirituais tornam-se mais evidentes, exigindo a expansão da atuação dos enfermeiros gerontólogos, em consultas de enfermagem. Objetivo: Identificar demandas clínicas atendidas e intervenções de enfermagem implementadas durante as consultas de enfermagem gerontológica. Método: Revisão integrativa de estudos originais realizada entre novembro de 2021 e julho de 2022, publicados nos últimos cinco anos em inglês, espanhol e português, nas bases: Scopus, MEDLINE/PubMed, BIREME/LILACS/BDENF/IBECS/BVS, SciELO e Google Scholar, pelos descritores: "Consultation Geriatric”, “Nursing Consultation”, “Office Nursing”, “Nursing Process”, “Aging”, “Gerontology” e “Geriatric Nursing”. Utilizou-se o Rating System for the Hierarchy of Evidence for Intervention para determinar o nível de evidência da amostra final. Editoriais, estudos de revisão e artigos duplicados foram excluídos. Resultado: Identificou-se dez artigos nas temáticas: Autocuidado; Enfermagem avançada; Síndrome do idoso frágil; Teleconsulta; Jogo de tabuleiro; eConsult; instrumento baseado no modelo de Roy não adaptativo; avaliação geriátrica abrangente; educação sexual e avaliação da administração e uso de medicamentos da NANDA-I, NOC e NIC. Conclusão: As demandas do âmbito clínico levantadas às consultas de enfermagem gerontológica são de origem neurocognitiva, neuromotora, hormonal, nutricional, socioemocional, psicológica e problemas fisiológicos associados e evidenciados por complicações. As intervenções no formato presencial e a distância são realizadas de forma isolada por certo agravamento, são guiadas por linguagens padronizadas de taxonomias e por teorias de Enfermagem, devido ao uso de ferramentas, escalas e instrumentos validados para uma avaliação sistemática do paciente.
“Nenhuma Pessoa Idosa Merece Passar por Isso”
Authors: Félix Rosas de Vasconcelos Emília Carolina , Pinheiro Costa e Silva Susanne , De Lima Maciel Maria Joycielle , Rodrigues de Lima Amanda Alana , Pereira Aprigio Silva Kelaine , Costa e Silva Mirella Maria
Published: January 2024

Introdução: A violência contra idosos é um fenômeno crescente, ocasionando prejuízos à saúde, com diferentes desfechos e consequências às vítimas.  A chance de idosas sofrerem-na no âmbito familiar supera a dos homens, sendo o gênero um fator de risco considerável.
Objetivo: Analisar a compreensão da violência contra pessoas idosas segundo mulheres gerontes.
Metodologia: Pesquisa descritiva com abordagem qualitativa desenvolvida com 22 idosas de uma comunidade no estado da Paraíba, Brasil, escolhidas por conveniência. Utilizou-se para coleta de dados entrevistas semiestruturadas, processadas pelo software Iramuteq, com posterior Análise de Conteúdo.
Resultados: Foram evidenciadas cinco classes: ciclo de violência; rede de apoio ao idoso vítima de violência; Vivência de situações violentas; violência financeira; e simbologia da violência na sociedade, as quais denotam compreensão da violência envolvendo os diferentes tipos. Apoiam-se nos fatores da vivência familiar, cultura e outros, consubstanciando o profissional de saúde como fundamental para o desfecho. O gênero influenciou no que concerne ao olhar lançado sobre a violência física e psicológica, bem como na relevância dada às equipes de saúde para identificação de ocorrências e prevenção de possíveis danos.
Conclusão: Os diversos tipos de violência contra a pessoa idosa foram reconhecidos, incluindo fatores individuais, comunitários e sociais no ciclo violento. Além disso, associaram o envelhecimento a maior suscetibilidade para sofrer violência, independente da tipologia. Destaca-se a potencialidade do serviço de saúde na assistência à pessoa idosa vítima de violência, elucidando casos e atuando precocemente para interrupção dos ciclos perpetrados, exigindo a necessidade constante de atualização profissional para lidar com situações detectadas.
Competências do enfermeiro no cuidado a pacientes com acidente vascular cerebral elegíveis à terapia trombolítica
Authors: Fochesatto Michele Marcon , Salbego Cléton , Ferreira Pacheco Tamiris , Bitencourt Toscani Greco Patrícia , Verza Bertelli Samuele , De Oliveira Tedesco Letícia Bibiana , Borges Leonardo
Published: January 2024

Introdução: O acidente vascular cerebral isquêmico tem como tratamento a terapia trombolítica, aplicada ainda na fase aguda, promovendo melhora importante nas sequelas acarretadas por este agravo. Considerando a complexidade da terapia trombolítica, torna-se necessário que os enfermeiros compreendam suas competências para auxiliar no cuidado.
Objetivo: Identificar evidências científicas acerca das competências do enfermeiro no cuidado a pacientes com acidente vascular cerebral elegíveis à terapia trombolítica.
Metodologia: Revisão integrativa composta por seis etapas em seis etapas (elaboração da questão, busca na literatura, coleta de dados, análise, discussão e apresentação da revisão), realizada nas bases de dados MEDLINE, LILACS, BDENF, IBECS, PubMed, Scopus, Web of Science, Embase e CINAHL. A busca foi realizada entre agosto e setembro de 2022 adotando como critérios de inclusão estudos primários; gratuitos, disponíveis eletronicamente na íntegra; nos idiomas inglês, português e espanhol. Foram obtidos inicialmente 2.830 estudos, os quais passaram por uma seleção, onde foram incluídos aqueles que atendiam os critérios previamente estabelecidos.
Resultados: Com base nos doze estudos incluídos nesta revisão identificaram-se competências voltadas à três atividades do cuidado: gestão do cuidado como trabalho em equipe, códigos, fluxos e protocolos, assistência ao paciente antes, durante e após a utilização da terapia trombolítica e educação em saúde para equipe, pacientes e familiares.
Conclusão: Os achados desta revisão puderam evidenciar as competências do enfermeiro no cuidado aos pacientes elegíveis a terapia trombolítica, as quais perpassam diferentes áreas de atuação do enfermeiro. Para este estudo prevaleceram as competências assistências, seguida por competências gerenciais.
The role of neophobia in a pioneer olfactory enrichment for amazons, macaws, and toucans
Authors: Hernández Carmen , Barja Isabel
Published: January 2024

Introduction: Despite sensory enrichment being critical for ensuring the well-being of captive wild animals, smells are not being included in enrichment protocols for birds. For this group, neophobia can be a problem when it comes to implementing new enrichment devices. Objective: Here, we aim to explore how participation in an olfactory enrichment and latency times varied between bird taxonomic groups (Amazona spp. / Ara spp. / Ramphastos spp.). Methods: For this, we exposed 257 birds to a scent enrichment, and we register which individuals engaged with it and the time they took to interact with it. Results: We discovered that toucan’s participation in the enrichment was significantly higher compared to amazons and macaws. Furthermore, latency time to interact with the enrichment was significantly higher in amazons. Our findings could suggest that toucans are neophilic species which could benefit from higher exploration rates. Amazons on the contrary seem to be particularly neophobic, possibly because of their less opportunistic feeding habits compared to toucans and their higher vulnerability to be preyed compared to macaws. Conclusion: These results point out that olfactory enrichment is appealing for toucans while a more natural design using smells inside familiar objects could be more successful for psittacids.
Significance of teff (Eragrostis tef (Zucc.) Trotter) as a new fodder crop for Bulgaria
Authors: Cholakova A. , Zhelyazkova Ts. , Gerdzhikova M.
Published: January 2024

Abstract. This review article aims to summarize global studies relating to the distribution, biological characteristics, productivity and cultivation technology for grain and green mass from teff (Eragrostis tef). Teff has the shortest vegetation period among cereals, good adaptability to varied environmental conditions and high drought resistance. In the world, it is gaining popularity as a healthy grain food, especially suitable for people suffering from celiac disease, due to the lack of gluten in the grain and a good source of omega fatty acids, vitamins and minerals. Teff is the crop with the shortest vegetation among the cereals – it ripens for 50 to 90 days. It can successfully be sown as a second crop following early cereals. As fodder, it has good nutritional value compared to some basic fodder crops. It is used as food for ruminants and horses, compared to the quality of well-maintained natural grasslands. Straw is preferred more than that of the basic annual cereal crops in ratios as coarse fodder. Its application in industry is also feasible. Resistance against diseases and enemies, as well as the ability to choke weeds, makes it an economically efficient and ecological crop. While studies on teff in Bulgaria are limited, they indicate successful cultivation in the arid conditions of Southern Dobrudzha. This crop, unknown to our producers, could be included in the structure of field crops and take up areas that are not suitable for the traditionally grown cereal plants – wheat, barley, maize. For this purpose, it is necessary to study the impact of the climate at a local level on the development and productivity of teff. It is necessary to pay serious attention when choosing the production technology, in order to use the potential for the production of green mass and grain, and a possible choice for impact is the optimization of the seeding rate and fertilization.
Effect of physical form of starter feed on nutrient digestibility of dairy calves
Authors: Ganchev G.
Published: January 2024

Abstract. The present experiment aimed to compare the effect of the physical form of a starter for dairy replacement calves on some rumen fermentation parameters. Nine male calves 4 days old and averaging 41.3 kg (SD = 3.6) were divided into three groups. The calves were housed in individual hutches bedded with straw. The calves were weaned at the age of 56 days of age and remained in the experiment until they reached 70 days. Three different physical forms of starter feeds were tested: 1) Ground starter – starter in meal form with coarsely ground maize (GS); 2) Pelleted starter (PS); and 3) Textured starter – a mixture of whole maize grain plus pelleted protein concentrate (TS). The ingredients and chemical composition of the three starter feeds were similar. The calves from all groups received 4 L of whole milk until 56 days of age. The liquid feed was provided twice daily from 4 to 35 days of age, and once daily from 36 to 56 days. From 35 days of age, calves were offered a free choice of alfalfa hay. OM digestibility was lower in calves that received ground starter compared to calves fed pelleted starter and textured starter. Apparent total tract digestibility of CP was the lowest in calves fed GS compared to those receiving PS and TS (P <0.05). No statistically significant difference in CP digestibility was observed between PS and TS-fed calves. EE digestibility was significantly lower in calves that received GS compared to those that received PS (P <0.05), but not different from EE digestibility in calves fed TS. The highest EE digestibility was that in PS-fed calves. CF digestibility was the highest in calves that received PS and the lowest in those fed GS, with significant differences (P <0.05). There was no significant difference in NFE digestibility among tested physical forms of starter feeds.
Analysis of energy consumption parameters in wheat harvesting using grain harvesters
Authors: Tihanov G.
Published: January 2024

Abstract. The paper analyses the energy consumption parameters of three grain harvesters for harvesting wheat. It has been found from the studies that the nominal throughput of the two harvester models K1 and K2 is very close, 7.88 kg/s on average, while for the third harvester K3 it is 9.33 kg/s or 16% higher than the two harvesters. In addition, the direct energy consumption of the observed three harvester models has been established, which averaged 312.57 MJ/t. The consumption of diesel fuel for the harvest of 1 ton of wheat with the harvesters has been determined, and the average consumption was 7.46 kg/t. The average total energy consumption of the three grain harvesters has been determined (1.19 GJ/t), ranging from 1.15 GJ/t to 1.24 GJ/t. From the obtained results, it can be seen that the lowest result has been obtained with harvester K3, since it has the largest working width of the header and the unloading of the grain hopper takes place while moving.
Growth response of soybean (Glycine max L.) varieties in biochar-amended typical alfisol in Lafia, Nasarawa State, Nigeria
Authors: Mshelmbula B.P. , Hussaini H.A. , Kana H.A. , Akinyosoye S.T.
Published: January 2024

Abstract. In Lafia, Nasarawa State, a study was conducted to assess the growth response of Soybean (Glycine max) genotypes cultivated with Rice Husk Biochar. Two genotypes, T.G.S 1448 and T.G.S 1449, provided by the State's Nasarawa Agricultural Development Program (NADP), were used. The experiment was conducted using three replicates in a Complete Randomized Block Design (CRBD). Four levels of rice husk Biochar were used in the treatments: 0, 60, 120, and 180 g/pot. The TGS1448 genotype, when subjected to the 180g biochar treatment (B180g), had the highest number of leaves (70.33), significantly more than the control which had the fewest leaves (56.00), and the other treatments. The variety TGS1449 exposed to biochar treatment B180g had the maximum plant height (59.33cm), which was substantially higher than the control (50.60) and the other treatments. The same pattern was seen in the TGS1448 variety when it was subjected to the biochar treatment B180g. After 9 weeks, plants with 180g biochar-amended soil produced 11 seeds per plant, whereas control plants did not produce pods or seeds. The study concluded that the addition of biochar to the soil significantly enhanced plant growth in the growth-restricted alfisol.
Using latent class analysis to identify different clinical profiles according to food addiction symptoms in obesity with and without binge eating disorder
Authors: Aloi Matteo , Liuzza Marco Tullio , Rania Marianna , Carbone Elvira Anna , de Filippis Renato , Gearhardt Ashley Nicole , Segura-Garcia Cristina
Published: January 2024

Background and aims

Existing research suggests that food addiction (FA) is associated with binge eating disorder (BED) and obesity, but the clinical significance of this relationship remains unclear. This study aims to investigate the different clinical profiles of FA symptoms among patients who have obesity with/without BED using latent class analysis (LCA).

Methods

307 patients (n = 152 obesity and BED, n = 155 obesity without BED) completed a battery of self-report measures investigating eating psychopathology, depression, emotional dysregulation, alexithymia, schema domains, and FA. LCA and ANOVAs were conducted to identify profiles according to FA symptoms and examine differences between classes.

Results

LCA identified five meaningful classes labeled as the “non-addicted” (40.4%), the “attempters” (20.2%), the “interpersonal problems” (7.2%), the “high-functioning addicted” (19.5%) and the “fully addicted” (12.7%) classes. Patients with BED and obesity appeared overrepresented in the “high-functioning addicted” and “fully addicted” classes; conversely, patients with obesity without BED were most frequently included in the “non-addicted” class. The most significant differences between the “high-functioning addicted” and “fully addicted” classes versus the “non-addicted” class regarded heightened severity of eating and general psychopathology.

Discussion and conclusions

The results bring to light distinct clinical profiles based on FA symptoms. Notably, the "high-functioning addicted" class is particularly intriguing as its members demonstrate physical symptoms of FA (i.e., tolerance and withdrawal) and psychological ones (i.e., craving and consequences) but are not as functionally impaired as the “fully addicted” class. Identifying different profiles according to FA symptoms holds potential value in providing tailored and timely interventions.
Comparison of the risk of pain in the lumbar spine in people performing office work and physical work
Authors:   Institute of Health Sciences, Medical College, University of Rzeszów, Rzeszów, Poland, Pop Teresa , Pokrywka Joanna ,   Activ, Gabinet rehabilitacji, Boguchwała, Poland, Skrzęta Małgorzata ,   Institute of Physical Culture Sciences, Medical College, University of Rzeszów, Rzeszów, Poland, Szczygielska Dorota ,   Institute of Health Sciences, Medical College, University of Rzeszów, Rzeszów, Poland, Rusek Wojciech ,   Rehabilitation Centre Rehamed-Center Sp. z o.o, Tajęcina, Poland, Adamczyk Marzena ,   Rehabilitation Centre Rehamed-Center Sp. z o.o, Tajęcina, Poland, Baran Rafał ,   Institute of Health Sciences, Medical College, University of Rzeszów, Rzeszów, Poland, Baran Joanna ,   Institute of Health Sciences, Medical College, University of Rzeszów, Rzeszów, Poland
Published: January 2024

Introduction: Pain in the area of the lumbar spine has become a serious problem not only in medicine, but also in society. Lack of knowledge and errors resulting from improper load during professional work lead to the formation of microtraumas, and thus permanent changes in the structure of the spine. The aim of the study was to assess the incidence of pain in the lumbar spine in people performing office work and physical work. Material and methods: The study included 70 people of both sexes in the age groups below 18, 18–25, 26–31, and over 40. The respondents were divided into two groups: manual workers – 39 people and office workers – 31 people. The study used a self-authored questionnaire, a standardized Oswestry questionnaire and the VAS pain scale. Results: Pain in the lumbar spine is more common in people who work physically at work. Treatment, after the diagnosis was made, was started by 20 subjects (87.0%). They were all physically working respondents and 62.5% of people working in a sitting position (p=0.011). The impact of pain on functioning in everyday life was assessed in ten aspects using the Oswestry questionnaire. No differences were found between the influence of pain on the size of the limitations of the two groups (p>0.05). The greatest limitations of the respondents were found in terms of the intensity of the pain experienced and changes in its intensity, as well as in the performance of lifting and sitting activities. Conclusions: Regardless of the nature of the work performed, most professionally active people experience pain in the lumbar spine, but it occurs more often in people who work physically. For people who perform manual work, the frequency of pain is defined as “sporadic”, while among office workers, pain occurs more often – several times a month.
Zastosowanie progresywnej relaksacji Jacobsona w leczeniu zaburzeń psychiatrycznych
Authors:   Zakład Fizjoterapii, Wydział Nauk o Zdrowiu, Gdański Uniwersytet Medyczny, Polska, Kodzik Aneta , Siek Bartłomiej ,   Zakład Historii i Filozofii Nauk Medycznych, Wydział Nauk o Zdrowiu, Gdański Uniwersytet Medyczny, Polska, Gworys Kamila ,   Klinika Rehabilitacji Medycznej, Wydział Nauk o Zdrowiu, Uniwersytet Medyczny w Łodzi, Polska, Szamotulska Jolanta ,   Zakład Fizjoterapii, Wydział Nauk o Zdrowiu, Gdański Uniwersytet Medyczny, Polska, Hansdorfer-Korzon Rita ,   Zakład Fizjoterapii, Wydział Nauk o Zdrowiu, Gdański Uniwersytet Medyczny, Polska, Zwoliński Tomasz ,   Klinika Rehabilitacji, Wydział Nauk o Zdrowiu, Gdański Uniwersytet Medyczny, Polska
Published: January 2024

Introduction: The goal of the article is to present the state of tests and discussion concerning the use of Jacobson’s progressive muscle relaxation (PMR) in psychiatric patients. It is assumed that adding PMR into the process of treating this group of patients is a reasonable therapeutic procedure. Material and methods: An analysis of literature indexed in databases of Scopus and Medline in the years 2001–2021 was performed. Included were articles presenting results of clinical tests and casuistic works. The subject terms and original key words were used as the search criteria. Results: Based on previously carried out literature examination, the conclusion was reached that the use of PMR is a reasonable therapeutic procedure aiding the treatment process and relapse prevention in psychiatric patients. Conclusions: PMR: decreases the levels of anxiety, stress, improves the quality of sleep and reduces symptoms of depression; it can be implemented as a complementary treatment to reduce the fear levels in hospitalized psychiatric patient; furthermore it has significant use in secondary prevention during the treatment process of patients with schizophrenia.
Prognostic significance of catestatin in patients with primary hypertension and type 2 diabetes mellitus
Authors: Pankova Olena , Korzh Oleksii
Published: January 2024

The aim of this study was to determine predictors of cardiovascular complications of arterial hypertension (AH) and type 2 diabetes mellitus (T2DM) and investigate the prognostic potential of catestatin (CST) and relaxin-2 (RLN-2) in this patient population.
Materials and methods. The research was performed in accordance with all ethical principles of the Declaration of Helsinki. All study participants signed a written informed consent. This study involved 106 patients with primary hypertension and 30 healthy volunteers. 55 hypertensive patients had comorbid T2DM. Plasma CST and RLN-2 levels were measured by an enzyme-linked immunosorbent assay. Major adverse cardiovascular events (MACE) were collected during 12-month follow-up via telephone interviews at visits in months 3, 6, 9, and 12. The end points of this study were acute myocardial infarction, ischemic stroke, acute heart failure and cardiac death. Statistical data analysis was performed using the SPSS 25.0 statistical software.
Results. 13 end-points were registered in patients with AH during the 12-month follow-up period, but the difference in frequency of MACE occurrence between patients with AH and T2DM and hypertensive patients without T2DM was insignificant (p=0.181). The Cox proportional hazard model indicated CST (p=0.01), but not RLN-2 (p=0.20), as an independent predictor of MACE in hypertensive patients. Age (p=0.01), AH duration (p=0.03), presence of T2DM (p=0.03), HOMA-IR index (p=0.02), insulin (p=0.02) and uric acid levels (p=0.02) were also established as independent factors of end-points occurrence.
Conclusions. CST is an independent factor for predicting cardiovascular complications of AH, which allows us to consider it as a prognostic biomarker in patients with AH, especially hypertensive patients with comorbidity T2DM
Effects of non-steroidal anti-inflammatory agents on systemic hemostasis during the most acute period of cold injury in rats
Authors: Shtrygol’ Sergiy , Taran Andrii , Yudkevych Tetiana , Lytkin Dmytro , Lebedinets Iryna , Chuykova Polina , Koiro Olga
Published: January 2024

Non-steroidal anti-inflammatory drugs (NSAIDs) have recently been considered promising agents for the prevention and treatment of cold injuries. The results of previous studies demonstrate a distinct frigoprotective effect of diclofenac sodium and etoricoxib.

The aim of the study: to assess the impact of diclofenac sodium and etoricoxib, as the most effective frigoprotectors among NSAIDs, on coagulation indicators during the most acute phase of cold injuries using an acute model of general cooling in rats.

Materials and Methods: The experiment was carried out using 41 outbreed male rats weighing 310±10 g. Cold injury was induced by acute general cooling (exposure to –18 °C for 2 hours). Diclofenac sodium (7 mg/kg) and etoricoxib (5 mg/kg) were administered intragastrically 30 minutes before the onset of cold exposure. Rectal temperature was measured before and after cold exposure. Immediately after exposure, plasma was used to determine prothrombin time (PT), thrombin time (TT), activated partial thromboplastin time (APTT), fibrinogen levels, and in blood serum – the residual amount of prothrombin, thrombin, fibrinogen, as well as D-dimer using species-specific immunoenzymatic analysis kits.

Results: Etoricoxib and especially diclofenac sodium significantly reduced the degree of hypothermia (rectal temperature decreased by 1.3 % and 1.9 %, respectively, compared to a 5.4 % decrease in the control group, p < 0.05). In the acute phase of cold injury in the untreated control group, there was a significant increase in D-dimer (by 2.7 times) and fibrinogen content (by 1.9 times) in blood serum, alongside a 21.7 % increase in thrombin time, indicating a heightened risk of thrombus formation and DIC syndrome development. The other coagulation indicators did not show significant changes. Both diclofenac sodium and etoricoxib significantly reduced elevated D-dimer and serum fibrinogen, normalizing thrombin time and indicating an antithrombotic effect. There was no significant difference in the effect of both NSAIDs on blood coagulation status.

Conclusions: The acute phase of cold injury demonstrates a dangerous shift in blood coagulation towards thrombus formation and DIC syndrome development. Prophylactic use of diclofenac sodium and, to a lesser extent, etoricoxib displays an anti-hypothermic effect, reducing the risk of thrombosis and DIC syndrome. This proves the expediency of using these NSAIDs for acute cold injury
Conducting biological tests in the development of self-emulsifying drug delivery systems with simvastatin
Authors: Bodnar Liubov , Lytkin Dmytro , Polovko Nataliia
Published: January 2024

The aim of the study was to compare the hypolipidemic activity of the developed self-emulsifying drug delivery systems with simvastatin with reference samples of the substance and the finished drug product of industrial production.
Materials and methods. The substance of simvastatin (India, s. DK40-2005021, 99.09 %, introduced into the composition of self-emulsifying compositions based on castor oil (Ukraine), polyethylene glycol 40 hydrogenated castor oil (India), Tween 80 (Ukraine), glycerol monostearate (Gustav Heess GmbH, Germany) or polyethylene glycol 100 stearate (ERCA, Italy). Reference samples were Simvastatin-Sandoz (Salutas Pharma, Germany, series LX5161) and simvastatin in pure form.
The experimental animals were Syrian hamsters aged 2 months. Hyperlipidemia was modeled by means of an alimentary load. To assess the state of lipid metabolism in animals, the content of triacylglycerols, total cholesterol, low-density lipoprotein and high-density lipoprotein in the blood serum was determined by colorimetric enzymatic methods using the appropriate standard reagent kits "Triacylglycerols F" HP022.02, "Cholesterol F" HP026.02, "Cholesterol-LDL F" HP026.05 and "Cholesterol-HDL F" HP026.04 (LLC SPE "Filicit-Diagnostics", Ukraine) on a semi-automatic biochemical analyzer MapLab Plus (BSI, Italy).
Results. The reference samples had similar dose-dependent efficacy parameters. At the same time, the test samples, also having similar dose-dependent effects, in absolute terms at the maximum concentration reduced the amount of low-density lipoprotein and total cholesterol more effectively than the reference samples. When using the test samples in their average concentration, the level of triglycerols was significantly reduced, which is rather a concomitant effect of simvastatin.
Conclusions. The improvement of the overall efficacy of simvastatin when it is introduced into self-emulsifying drug delivery systems has been proved, which is associated with the modification of pharmacokinetic parameters by improving the solubility of the substance in the aqueous environment of the gastrointestinal tract
Intensity of endoplasmic reticulum stress, autophagy, and apoptosis in the cerebral cortex of rats with chronic ethanol consumption under the influence of the complex compound of germanium with nicotinic acid
Authors: Nizhenkovska Iryna , Kuznetsova Olena , Narokha Violetta
Published: January 2024

The aim of the research – to determine the level of BAX, caspase-3, GRP78, IRE1 and Beclin-1 in the cerebral cortex of rats with chronic ethanol consumption and under conditions of exposure to the germanium complex with nicotinic acid (MIGU-1).
Materials and methods. Female rats had free access to 20 % C2H5OH as the only source of fluid for 110 days. Starting from the 90th day, the animals were injected with MIGU-1 (10 mg/kg/day, IP). The expression level of BAX, caspase-3, GRP78, IRE1 and Beclin-1 in the tissue was determined by Western blot analysis.
Results. In rats with chronic ethanol consumption, the level of BAX-dimer increased by 2.06 times (p˂0.001). The introduction of MIGU-1 caused a decrease in the level of BAX-dimer by 1.42 times (p˂0.05). In rats with chronic ethanol consumption, the level of caspase-3 increased by 2.12 times (p˂0.05), cleaved caspase-3 increased by 6.37 times (p˂0.05). When MIGU-1 was administered, the level of caspase-3 decreased by 1.73 times (p˂0.05). Under the conditions of MIGU-1 administration, protein bands of cleaved caspase-3 were reduced to an undetectable level. In rats with chronic ethanol consumption, the level of GRP78 increased by 1.72 times (p˂0.05). After administration of MIGU-1, no changes in the level of GRP78 were recorded. Long-term ethanol consumption increased the levels of IRE1 by 1.74 times (p˂0.05) and p-IRE1 by 2.7 times (p˂0.001). In the presence of MIGU-1, the levels of IRE1 and p-IRE1 did not change. Under the conditions of chronic ethanol consumption, an increase in the levels of Beclin-1 by 2.33 times (p˂0.001) and p-Beclin-1 by 4.69 times (p˂0.001) was observed. Administration of MIGU-1 did not affect the level of Beclin-1, while the level of p-Beclin-1 decreased by 3.09 times (p˂0.001).
Conclusions. Long-term ethanol consumption triggers metabolic changes in the cerebral cortex, resulting in ER stress, UPR activation, autophagy, and apoptosis. Administration of MIGU-1 alleviates ER stress by selectively inhibiting specific branches of apoptosis through effects on Beclin-1 levels, suggesting an effect of MIGU-1 on neuronal survival under chronic ethanol consumption
Exploring perceptions of students on safety and security from selected south African historically disadvantaged institutions
Authors: Lekganyane John Kgatla , Maluleke Witness , Barkhuizen Jaco
Published: January 2024

Students from distinct regions and even abroad flock to campuses of Higher Education Institutions (HEIs) to broaden their knowledge in diverse fields of study. These institutions offer a wide array of academic, social and sports-related programs. However, safety remains a major concern for students worldwide. The increasing number of cases of victimization on and around campuses, including at the Historically Disadvantaged Institutions (HDIs), has necessitated the serious consideration of students' safety. This study aims to explore students' perceptions of safety, as it focuses on Two (02) South African HDIs, specifically focusing at Universities of Limpopo (UL) and Venda (UNIVEN) of South Africa. This study adopted the qualitative approach, employing the case study design, with the aid of exploratory objectives. About Twenty (20) participants were selected using the non-probability: Purposive sampling to take part in semi-structured, face-to-face interviews. The collected data were analysed using the inductive Thematic Content Analysis (TCA) with inductive reasoning.

The findings discovered that inadequate lighting in certain areas of the campus, insufficient Closed-Circuit Television (CCTV) in some student residences, the absence of police patrols around the campus, and the unavailability of emergency phones to contact security officials are factors that contribute to the feeling of insecurity in both on-campus and off-campus housing. The study also found that students are hesitant to travel alone at night, regardless of whether they are living on-campus or off-campus. Not surprisingly, the study found that students who reside off-campus are more afraid of sexual violence than those who reside in on-campus housing. With respect to recommendations, it is advised that it is necessary to install CCTVs in all leased off-campus accommodations as well as the on-campus residences to keep students secure. For students living off-campus, there should be enough transportation to help their movement to and from their respective homes. In addition, it is recommended that police patrols be visually evident on the campus as well as near off-campus accommodations where many students reside
Mechanical properties of the bone-implant systems in conditions of the stable functional osteosynthesis
Authors:   Bashkir State Medical University of the Ministry of Health of the Russian Federation, Minasov Timur , Skryabin Vladimir ,   Occupational Health Hospital No. 9 named after M.A. Tverie, Sotin Alexander ,   Perm National Research Polytechnic University, Minasov Iskander ,   Bashkir State Medical University of the Ministry of Health of the Russian Federation, Saubanov Radmir , Fayzullin Ayaz , Vakhitov-Kovalevich Ruslan
Published: January 2024

Fractures of the diaphysis of leg bones make up 45% of all long bone fractures, they are one the most common injuries to the bones of the limb segments, the treatment of which is accompanied by a large number of complications, therefore the problem of improving the treatment of patients with this injury is still relevant for present traumatology and orthopedics. The use of compression distraction systems, intramedullary and extramedullary osteosynthesis systems allows a stable functional osteosynthesis and eliminates the need for additional gypsum immobilization of a segment or limb in the postoperative period. Biomechanical relations in the bone-implant system in conditions of a stable functional osteosynthesis constitute an important factor allowing to objectify the mode of motion rehabilitation in the early postoperative period. This work studies the results of the comparative bench tests of groups of cadaver tibia in experimental injuries of type 42 A 1.1. (according to the Association for Study of Internal Fixation (AO/ASIF)) synthesized with different types of implants, such as Fixion expanding system of fixation, external fixation devices, Limited Contact Dynamic Compression Plate (LC-DCP) and blocked intramedullary osteosynthesis system (BIOS)). Each system was axially compressed using INSTRON 1185. Resistance to axial compression has been analyzed. It is noted that all these types of fixations increase the strength of the systems in the range of 22–81% compared to the intact specimens. Intraosseous fixation systems demonstrated the highest strength, which has the most optimal biomechanical relations in the bone-implant system, allowing to objectify the regime of motion rehabilitation.
Caracterización de los sistemas de producción de ovinos de pelo en Baja California, México
Authors: Lara Rivera Ana Laura , Parra-Bracamonte Gaspar Manuel , Flores-Garibay Rodrigo , Vazquez-Armijo José , Martínez-González Juan , Magaña-Monforte Juan G. , Moreno-Medina Victor
Published: January 2024

El presente estudio describe las principales características de los sistemas de producción de ovinos de pelo en el Estado de Baja California, México. La información relacionada con el sistema de producción ovina se recopiló mediante encuestas aplicadas a ovinocultores tomando en consideración diversos aspectos de manejo general como son el tipo de sistema de producción, selección de sementales, prácticas de alimentación y crianza. Se realizó un análisis de componentes principales para evaluar y encontrar las mejores variables definitorias. Los resultados sugieren que existe un área de oportunidad para el sistema de producción de ovinos de pelo en Baja California. Asimismo, variables específicas permiten una mejor estratificación de los sistemas de producción. Se destacan algunas limitaciones que deben ser resueltas para impulsar el desarrollo de la producción de carne de ovino de pelo en el noroeste del país.