bluuebunny/crossref_metadata_2025 huggingface dataset:
A CASE OF UNEXPLAINED RENAL FAILURE IN A YOUNG CHILD
Authors: Goswami Himanish , Bora Mitul , Borkotoky Rekha Khaund , Das Tonmoy
Published: November 2024

Acute lymphoblastic leukemia (ALL) is a common pediatric malignancy, though its presentation with acute kidney injury
(AKI) and spontaneous tumor lysis syndrome (TLS) is rare and presents significant clinical challenges. We report the case
of a 10-year-old boy who presented with bilateral cervical lymphadenopathy, hypertension, and renal impairment. Initially treated conservatively
at a local hospital, his condition deteriorated, leading to referral to our center. On further evaluation, the patient exhibited decreased urine output,
weight loss, night sweats, and worsening renal function. Laboratory findings revealed AKI and hyperuricemia, raising suspicion of spontaneous
TLS. Subsequent diagnostic workup, including bone marrow aspiration, biopsy, and flow cytometry, confirmed ALL with aleukemic
features—characterized by the absence of circulating blasts in peripheral blood. The patient was managed with allopurinol, aggressive hydration,
and, following hematology consultation, chemotherapy initiation at an oncological center. This case highlights the challenges in diagnosing and
managing ALL with AKI and spontaneous TLS, emphasizing the importance of early recognition and multidisciplinary care to address rapidly
progressing metabolic disturbances.
Unusual Association: Dermatomyositis Diagnosis Tied to Rare Presence of TPO Autoantibodies
Authors: Roy Dr Pushpita , Banik Dr Dipaloke , Chowdhury Dr Minhaj Uddin Ahmad , Chowdhury Dr Utpal
Published: November 2024

The co-occurrence of autoimmune diseases is prevalent and largely documented. However, the simultaneous presence of dermatomyositis and autoimmune thyroid disorders remains comparably uncommon, despite both being autoimmune in nature. In this report, we present a case of a 60-year-old Bangladeshi American individual delineating clinical manifestations consistent with dermatomyositis, including Gottron's papules, the V-sign, Shawl sign, and skin abnormalities, noticeably hypopigmented areas on the scalp and face. Although muscle biopsy results in this patient did not align strictly with classical dermatomyositis, they illustrated a combination of necrotizing myopathy and dermatomyositis. Notably, laboratory findings conceded the presence of TPO autoantibodies, despite the absence of clinical signs or symptoms of hypothyroidism. This discovery recommends the possibility of an underlying autoimmune thyroid condition. Our case prompts consideration of whether a distinct subtype of dermatomyositis may be associated with autoimmune thyroid conditions, even in the absence of overt thyroid manifestations.
Relationship between Ultrasonographic Brain Findings and Outcomes of Perinatal Asphyxia
Authors: Ferdousi Tahmida , Akter Shaila , Tabassum Sadia , Nargis Nilima
Published: November 2024

Introduction: Perinatal asphyxia is one of the most common causes of neonatal morbidity and mortality in most countries of the world. Asphyxia (insufficient oxygen supply) can lead to severe hypoxic ischaemic organ damage in newborns followed by a fatal outcome or severe life-long pathologies. Ultrasound (US) has emerged as a powerful screening tool for the evaluation of a neonate with suspected perinatal asphyxia. Therefore, this study aimed to find a relationship between Ultrasonographic brain findings and immediate outcomes of perinatal asphyxia. Methods: This was a prospective analytical study carried out in the Special Care Baby Unit (SCBU), Department of Pediatrics, Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh from January 2018 to June 2018. In our study, we enrolled 200 newborn babies with perinatal asphyxia based on the selection criteria who were admitted to the special care baby unit within 24 hours. Results: The mean ± SD of age was 5.7±1.1 hours. Cranial sonographic findings show that 36.0% had cerebral oedema, 5.0% intraventricular bleeding, 3.0% showed focal cerebral infarction and 53.0% showed normal findings. Out of 164 patients who recovered from the illness, 98 patients had normal USG findings as opposed to 66 patients with abnormal USG. Among the expired cases, all (100%) had abnormal cranial USG findings. Conclusion: In our study, we found that there was a significant association between abnormal cranial USG findings and the immediate outcome of the asphyxiated newborn. The most common abnormality was cerebral oedema and IVH and it carried the highest mortality.
Ultrasonography (USG) Evaluation among Patients with Biliary Obstruction in a Tertiary Care Center
Authors: Muktadira Dr. , Rahman Dr. Meher Anges , Farjana Dr. Mir Naz , Islam Dr. Mahzabeen , Sharma Dr. NK
Published: November 2024

Background: Biliary obstruction is a blockage in the bile ducts that prevents bile from flowing from the liver to the small intestine. Objectives: This study aimed to assess the efficacy of ultrasonography (USG) among patients with a blockage in the bile ducts as known as biliary obstruction. Methods: This was a prospective observational study conducted at the Department of Radiology and Imaging at Sir Salimulliah Medical College Hospital, Dhaka, Bangladesh. This study included patients with clinical suspicion of biliary obstruction who underwent USG. Characteristics of the obstruction were evaluated for both benign and malignant lesions through USG. The findings were then correlated with ERCP, histopathology, or surgery to calculate the diagnostic performance of the former two modalities. Results: Out of 145 patients, 63 were in the malignant group and 82 were in the benign group. The sensitivity, specificity, and accuracy of detecting the nature of obstruction by USG were 33%, 84%, and 48.9%, respectively. The overall diagnostic accuracy of USG in predicting the site of obstruction was 64.3%. Hydatid Cyst and the Main Pancreatic Duct Stricture were the most accurate findings of USG. Conclusions: USG should be the initial screening modality of choice for predicting the level and nature of obstruction in patients with a clinical suspicion of obstructive jaundice.
Dengue Fever in Pregnant Women with a Favorable Outcome
Authors: D. Kalybekova K. , Abdimomunova B.T. , A. Akzholtoeva A. , Abinaya Iyngaran
Published: November 2024

Dengue fever is a viral infectious disease, it manifests itself from mild to severe severity, in some cases to fatal outcomes. The number of cases of dengue fever has been increasing in recent years. The results of many studies have also shown adverse effects on pregnant infected women. This article describes the clinical course of Dengue fever in pregnant women, which occurred in moderate severity and without complications. Dengue fever in a pregnant woman manifested itself in the form of complaints of pain in the epigastric region, bleeding gums and petechial hemorrhages within 1 day. She had a high fever for 5 days before going to the hospital. Upon admission, her body temperature was 37 °C, blood pressure was 110/80 mmHg, pulse rate was 80 beats per minute, respiratory rate was 20 beats per minute. She had mild dehydration, normal breathing and heartbeat. The height of the bottom corresponds to the gestation period of 31 weeks, and the fetal heart rate was 144 beats per minute. Petechiae measuring at least 1-2 m in diameter were found around her face, forearms and both basal areas. In a laboratory study, the results showed changes in the number of platelets in the form of thrombocytopenia, leukocytopenia and in the biochemical analysis of blood by increasing the concentration of C-reactive protein and the detection of antibodies in serum during serological analysis. Although many studies have shown that Dengue during pregnancy increases the risk of preeclampsia, hemorrhagic dengue fever (HLD), fetal distress, premature birth, cesarean section and maternal mortality and intrauterine development delay and stillbirth consequences. This clinical case concludes with favorable outcomes. But the physiological effects of dengue fever during pregnancy (for both mother and child), depending on the trimester, as well as research and treatment methods require further study, especially in the region of endemic zones and India.
New Innovations in Seed Morphology, and Plant Physiology for Crop Protection
Authors: Bano Areeba , Fatima Meraj , Ismail Muhammad , Ullah Ghufran , Hussain Hafiz Muhammad , Shahjahan Muhammad , Saleem Muhammad , Shahid Sehar , Ahmad Sohail
Published: November 2024

The seed is a mainly reproductive unit of the spermatophyta and links the subsequent generations. Other essential seed activities include survival in arid, cold, or other adverse conditions and dispersal. There is a lot of variety in the internal and external architecture of seeds. OsMKP1, a mitogen-activated protein kinase phosphatase, is encoded by GSN1. Rice glume cells proliferate when GSN1 expression is suppressed, producing larger but fewer rice grains. The GSN1 directly interacts with OsMAPK6 and dephosphorylates it, rendering it inactive. Thus, precise regulation of OsMAPK6 activity via reversible phosphorylation is essential for regulating the rice grain size. Some genes also negatively control the grain width and weight by inhibiting cell proliferation. The embryo, which is made up of cotyledons, hypocotyl, and radicle; the endosperm, which feeds the growing embryo; and the seed coat, which envelops the embryo and the endosperm, are the three main parts of plant seeds, each of which has unique biological functions and outcome. The growing seed can benefit from the ability to predict when a sugar burst would arrive through the phloem, since this would allow the seed to quickly adapt to its storage product synthesis. However, there are still certain obstacles that prevent the use against a variety of insect species. The adoption of various formulation procedures that improve dsRNA persistence and cellular absorption in insects is expected to overcome these issues, which are mostly related to the varying RNAi sensitivity of oral RNAi in insects. The CRISPR/Cas system has become the most popular being shown to be useful for editing the genome of plants, its uses in plants have grown significantly in comparison to other technologies.
Environmental Impact and Sustainable Practices in Aquaculture: A Comprehensive Review
Authors: Arshad Sana , Arshad Saba , Afzal Sumaira , Tasleem Faisal
Published: November 2024

Aquaculture is the fastest-growing food production sector, now contributing more to global fish biomass than capture fisheries. While much of this expansion has occurred over the past 50 years, it has been accompanied by numerous environmental challenges, including aquatic pollution driven by urbanization, industrialisation, harbour dredging, sand filling, pesticide runoff from agricultural activities, and land-use conflicts between aquaculture, industry, and tourism. These environmental concerns have heightened the focus on sustainability, particularly in relation to ecological preservation. This review explores the various types of waste generated by industries, households, and other establishments that are discharged into aquatic ecosystems, examining their potential impacts on aquaculture. In addition, it evaluates mitigation strategies aimed at reducing or eliminating these environmental threats. Increasing attention has been placed on raising awareness of environmental issues and adopting sustainable practices to minimise aquaculture's ecological footprint. While environmental degradation was not viewed as a critical issue in the early stages of the industry's development, it has now become a central concern across academic, governmental, industrial, and market sectors.
A A TECNOLOGIA NO AUXÍLIO À EDUCAÇÃO DE PESSOAS COM AUTISMO: ANÁLISE INTEGRADA DA PRODUÇÃO CIENTÍFICA
Authors: Mainardes Cristiane
Published: November 2024

Autism spectrum disorders (ASD) affect a significant number of people who have communication and socialization difficulties, resulting in several obstacles in the learning process. The number of students with autism has constantly expanded and has become the most prevalent disability at school age. When observing the literature, it is possible to conclude that research that addresses the implications of technologies in the education of people with ASD requires further exploration. Therefore, the present work aims to identify the dimension of studies on the relationship between autism, education and technology. The methodology adopted was a bibliometric analysis, using the Proknow-C method (Knowledge Developmend Process-Constructivist), in the Scopus and Web of Science databases. Among the results obtained are the authors who published the most on the topic (Beth Malow, Sarah Parsosn, Paul Shattuck and Mary Wagner); the analysis of the most relevant journals (Journal of autism and developmental disorders and Autism) and the analysis of the co-occurrence of keywords that were autism and technology. As for future research, there is a need to propose bibliometric analyzes that bring more results that address the integration between themes.
Kto ma sprawczość? Foto-esej o wielkomiejskich smartfonach
Authors: Filiciak Mirosław , Starzec Paweł
Published: November 2024

The article is devoted to a critical analysis of the agency of technology through the example of smartphones. Starting from infrastructural studies and empirical material recording user practices, the authors show how smartphones, as central elements of contemporary communication networks, shape both intimate and social aspects of life. Photography here makes it possible to reveal the invisible—and sometimes simply deliberately concealed—connections between technology and everyday life. It thus acts as a research tool that attempts to overcome the limitations associated with the lack of transparency of the area under analysis. English translation will follow soon.
„Siedzę przed kompem”. Jak wygląda praca w cyfrowym kapitalizmie?
Authors: Wojtyna Miłosz
Published: November 2024

Autora interesują kanoniczne formy wizualne towarzyszące pracy w cyfrowym kapitalizmie – czyli porządku ekonomiczno-informacyjno-kognitywnym, którego podstawą są ekrany, informacje i uwaga. Analizuje on zatem, jak wygląda dziś praca tam, gdzie do jej wykonywania niezbędne są ekrany; jakie wymiary ma wizualna część pracy; jak pracę tę przedstawiają artyści i teksty kultury popularnej. W artykule omawia liberalizację estetyki środowiska pracy zdalnej jako miejsca, które nie przynależy do pracodawcy, fetyszyzację estetyki stanowiska pracy i przestrzeni biurowej w dyskursach marketingowych; symulowanie fizycznej obecności za pomocą efektów wizualnych; kompulsję wizualizacji w komunikacji służbowej; „Zoom fatigue” i zmęczenie pracownika korporacji; wizualne wymiary czekania. Omówienie tych zagadnień ilustruje przykładami z tekstów kultury.
Who Has the Agency? A Photoessay on Metropolitan Smartphones
Authors: Filiciak Mirosław , Starzec Paweł
Published: November 2024

The article is devoted to a critical analysis of the agency of technology through the example of smartphones. Starting from infrastructural studies and empirical material recording user practices, the authors show how smartphones, as central elements of contemporary communication networks, shape both intimate and social aspects of life. Photography here makes it possible to reveal the invisible—and sometimes simply deliberately concealed—connections between technology and everyday life. It thus acts as a research tool that attempts to overcome the limitations associated with the lack of transparency of the area under analysis. English translation will follow soon.
Ekologie rurociągów. Splątane losy światłowodów i terenów wiejskich
Authors: Statosielski Nicole
Published: November 2024

Polski przekład rozdziału z książki „Sustainable Media: Critical Approaches to Media and Environment autorstwa Nicole Starosielski pt. „Pipeline Ecologies. Rural Entanglements of Fiber-Optic Cables (pp. 38–55, Taylor and Francis Inc., https://doi.org/10.4324/9781315794877).
Digital Entanglements
Authors: Pijarski Krzysztof
Published: November 2024

Introduction to the thematic issue on digital entanglements. The point of departure is the project by Ben Joseph Andrews and Emma Roberts entitled Turbulence that renders the experience of jamais vu: “the sudden appearance of reality no longer being real.”
Awareness on Carbon Footprints Among Politeknik Sultan Haji Ahmad Shah Students
Authors: Abd Karim Ernie Kulian , Mokhtar Saiful Hazman , Syed Ahmad Sharifah Adawiah
Published: November 2024

In this study, we aimed to investigate the awareness and actions related to carbon footprints among Politeknik Sultan Haji Ahmad Shah (Polisas) students. As the world's greenhouse gas emissions continue to rise globally, it is critical to assess people's attitudes and actions in tackling this environmental challenge, especially those of the younger generation. In addition to evaluating the students' views about the impacts of carbon emissions, the study also studied the students' actions to reduce carbon emissions. The study attempted to measure the carbon footprint values of Polisas students based on their daily activities using the Polisas Carbon Footprint Calculator. Using data from their regular monthly activities, students may estimate their carbon footprint with the help of this simple application, which helps them gain a better awareness of their environmental effects. Important information about the attitudes and behaviours of 406 participating students regarding carbon emissions was obtained through the distribution of questionnaires to them. The respondents' data was analysed using the Statistical Package for the Social Sciences (SPSS), and the results showed an average high mean of 3.68 for attitudes towards carbon emissions and 3.60 for actions connected to lowering carbon emissions. It suggests a positive inclination among Polisas students towards environmental consciousness and sustainable practices. The findings further highlight the monthly carbon footprint of Polisas students, calculated at 3287.14 kg of CO2. To contextualize this data, the Polisas Carbon Footprint Calculator recommends planting an average of 104 plants per month, equivalent to four trees per day, to offset their carbon emissions. It gives students a tangible understanding of their carbon footprint and encourages them to actively participate in carbon offsetting initiatives actively, fostering a sense of responsibility for their environmental impact. In conclusion, this study contributes valuable insights into the awareness, attitudes, and practices of Polisas students regarding carbon footprints. The implications of this study extend to the development of targeted environmental education programs and initiatives to enhance student's understanding of their contributions to carbon emissions. Moreover, the findings underscore the potential for instituting campus-wide sustainability measures and encouraging students to actively engage in carbon offsetting activities, thereby fostering a more environmentally conscious and responsible student community at Politeknik Sultan Haji Ahmad Shah.
Unlocking Project Success: A Guide to Project Management Fundamentals
Authors: - Swetha Sistla
Published: November 2024

Project management is a vital discipline that ensures the successful execution of projects across various industries. This white paper delves into the core principles and methodologies that form the foundation of effective project management. It explores the project life cycle, from initiation to closing, and highlights essential tools and techniques such as Work Breakdown Structures (WBS), Gantt charts, and risk management strategies. Additionally, the paper examines traditional and agile methodologies, providing insights into their applications and benefits. By understanding these fundamentals, project managers can enhance their ability to deliver projects on time, within scope, and on budget, ultimately driving organizational success.
Implementing Scalable Image Processing Pipelines in Cloud Environments for Healthcare Imaging Applications
Authors: - Akshat Bhutiani
Published: November 2024

In order to support healthcare imaging applications, this paper investigates the use of scalable image processing pipelines in cloud environments. A growing number of MRIs, CT scans and X-Rays are producing high resolution images, which means that processing, storing and analyzing these images in real-time requires effective solutions. The study focusses on improving image processing algorithms to use machine learning and utilizing cloud-based infrastructure to build adaptable and affordable pipelines that can handle big datasets. This method seeks to enhance the precision of medical image diagnostics to enable better healthcare outcomes.
Optimizing Salesforce Data Model Design for ISV Partners
Authors: - Praveen Kotholliparambil Haridasan
Published: November 2024

Salesforce provides a powerful platform to Independent Software Vendors (ISVs) for building and deployment applications, but the design of the data model poses challenges considering the multitenant architecture. A comprehensive review of Salesforce design model for ISV partners is delineated in this article which focuses on key considerations like performance optimization, data normalization, object relationships, and security practices. The article also explores the differences between the usage of standard and custom objects. It also addresses the importance of indexing, and other strategies for maintaining data integrity. Field encryption, record-level security, and package compliance are also addressed in this article. Consideration of these principles by the ISV partners will enable them to build high-performance and scalable applications to meet the diverse needs of the customers while staying within Salesforce's platform limitations.
QARIŞDIRICI QURULUŞLU APARATLARDA İSTİLİKVERMƏ PROSESİNİN EFEKTİVLİYİNİN ARTIRILMASI
Authors: Qasım Məmmədov, Şahsuvar Əsədzadə Qasım Məmmədov, Şahsuvar Əsədzadə
Published: November 2024

Qarışdırıcı quruluşlu aparatlarda istilikvermə prosesinin effektivliyinin artırılması, sənaye proseslərinin optimallaşdırılmasında mühüm bir yer tutur. Bu aparatlar, əsasən kimya və neft-qaz sənayesində geniş istifadə olunur. Araşdırmalar göstərir ki, qarışdırıcının konstruksiyası, qarışdırma sürəti və istilik mübadiləsi sahəsi kimi faktorlar, enerji səmərəliliyini yüksəltməkdə əsas rol oynayır. Bu faktorların optimallaşdırılması yolu ilə istilikvermə prosesindəki enerji istifadəsini azaltmaq və beləliklə, ümumi istehsal xərclərini aşağı salmaq mümkündür. Nəticədə, bu yanaşma sənaye təsərrüfatında enerji mənbələrindən daha effektiv istifadə etməyə və ekoloji təsirin azaldılmasına kömək edir. Gələcək tədqiqatlar, bu sahədəki yenilikləri və texnoloji irəliləyişləri dəstəkləməyə davam etməlidir.
Qarışdırıcı quruluşlu aparatların istilikvermə prosesinin effektivliyini artırmaq üçün mühəndislər və tədqiqatçılar çoxşaxəli yanaşmalar tətbiq edirlər. Xüsusilə, qarışdırıcıların həndəsi ölçüləri və qarışdırma mexanizmlərinin optimallaşdırılması, istilik ötürmə səthlərinin böyüdülməsi və işləmə parametrlərinin dəqiqləşdirilməsi istilik effektivliyinin artırılmasında mühüm addımlar hesab olunur. Həmçinin, avtomatlaşdırılmış idarəetmə sistemləri və qabaqcıl sensor texnologiyalarının tətbiqi ilə enerji istifadəsi daha da optimallaşdırıla bilər.
Bu texnoloji irəliləyişlərin praktik tətbiqi, sənaye müəssisələrinin enerji istehlakını azaltmaqla yanaşı, iş proseslərinin səmərəliliyini artırmaqda əsas rol oynayır. Nəticədə, bu yeniliklər sənaye təsərrüfatında xərclərin optimallaşdırılmasına və çevrəyə olan təsirin minimuma endirilməsinə imkan verir. İstilikvermə prosesinin effektivliyinin artırılması ilə bağlı davamlı araşdırmalar və təkmilləşdirmələr, bu sahədəki texnoloji və operativ yeniliklərin mütəmadi olaraq tətbiq edilməsini təmin edir.
Açar Sözlər: qarışdırıcı quruluşlu aparatlar, istilikvermə prosesi, enerji effektivliyi, optimallaşdırma, sənaye tətbiqləri, enerji səmərəliliyi.
Legal Certainty for Providing Preferential Tariffs in the ASEAN-China Free Trade Area (ACFTA) Agreement Based on Operational Certification Procedures (OCP) in Tax Court Decisions
Authors: Susanto Harry , Ardiansyah Ardiansyah
Published: November 2024

The ASEAN-China Free Trade Area (ACFTA) is an agreement made by the member countries of ASEAN and the People's Republic of China with the aim of promoting a stable and harmonious economy through the free flow of goods. ACFTA also supports the idea that barriers to international trade, both tariff and non-tariff, should be reduced or even eliminated, which is known as preferential tariffs. The countries involved in the ACFTA agreement agree that the Rules of Origin (ROO) provisions are necessary to obtain preferential tariffs. ROO establishes three criteria: Origin Criteria, Consignment Criteria, and Procedural Criteria. (Procedural Criteria).
The Procedural Criteria are regulated in the Operational Certification Procedures (OCP) in Appendix 1 of Attachment A of Annex 1 ROO. The OCP contains regulations regarding the time for submitting a Certificate of Origin (SKA) in order to obtain a preferential rate. There are parties that think about the implementation of OCP ACFTA in Indonesia, that further regulations on OCP cannot be made without an agreement from both sides to do so. Research conducted using a normative legal approach with data collection methods through literature study, concluded that there are still differences in the application of Operational Certification Procedures (OCP) in the imposition of preferential rates by customs officers and Tax Court judges in the region in resolving disputes regarding preferential tariff. Therefore, adjustments are needed in the legal products regarding the implementation of preferential tariff imposition, as well as an enhancement of legal understanding and reasoning in the Tax Court to provide legal certainty, justice, and benefits for all stakeholders.
Keywords: ACFTA, Preferntial Tariff, OCP.
LEGAL LIABILITY FOR UNAUTHORIZED MINING CRIMES (CASE STUDY OF BANDUNG HIGH COURT DECISION NUMBER 91/PID.SUS/2023/PT BDG)
Authors: Hamid Irwan Abdul , Sapari Papang
Published: November 2024

This research aims to examine how regulations concerning Mining Permits for People (Izin Pertambangan Rakyat/IPR) are viewed from a legislative perspective and to analyze the legal considerations of judges when imposing criminal sentences on perpetrators of illegal mining based on Bandung High Court Decision Number 91/Pid.Sus/2023/PT BDG. The research methodology used is normative juridical research, which involves the analysis of secondary data or literature.
The findings of this research are as follows: First, permits for mining activities in People’s Mining Areas (Wilayah Pertambangan Rakyat/WPR) with limited area and investment are known as People’s Mining Permits (IPR). Law No. 03 of 2020, which amends Law No. 04 of 2009 on Mineral and Coal Mining, and Government Regulation No. 25 of 2024, which amends Government Regulation No. 96 of 2021 on the Implementation of Mineral and Coal Mining Business Activities, include provisions on People’s Mining, as well as procedures and requirements for obtaining a People’s Mining Permit. Criminal sanctions and further penalties apply to those engaging in mining activities without authorization. Article 158 and Article 164 of Law No. 03 of 2020 concerning the Amendment to Law No. 04 of 2009 on Mineral and Coal Mining contain these provisions.
Second, the appeal was based on the fact that the panel of judges at the first level failed to carefully analyze the objections and misinterpreted the indictment articles based on the defense notes and evidence presented by the defendants. Article 158 of Law No. 03 of 2020, in conjunction with Article 55 Paragraph (1) of the Indonesian Penal Code, was a significant consideration for the judges in evaluating the first alternative indictment. According to the judges, this indictment was appropriate and accurate. Concerning the second indictment, Article 107(a) of Law No. 39 of 2014 on Plantations, in conjunction with Article 55 Paragraph (1) of the Penal Code, the High Court Judge stated that the Cibadak District Court Decision Number 365/Pid.Sus/2022/PN Cbd was not entirely accurate. The author argues that in interpreting and establishing Article 158 of Law No. 3 of 2020, which amends Law No. 4 of 2009 on Mineral and Coal Mining, the Public Prosecutor’s demands and the content of the indictment were incorrect.
A comprehensive review on analytical validation methods of cenobamate and upadacitinib
Authors: Yamarthi Venkateswara Rao
Published: November 2024

A new antiepileptic medication called cenobamate was just licenced to treat adult partial-onset seizures. By specifically focusing on the persistent sodium current, its special method of action lowers neuronal excitability and the spread of seizures. Cenobamate has been shown to be safe and effective in clinical trials, resulting in notable decreases in the frequency of seizures and enhancements in the patient's quality of life. Patients with uncontrollably occurring seizures may find it to be a desirable option due to its excellent pharmacokinetic profile and few medication interactions. This study examines the possible advantages and disadvantages of cenobamate use in the treatment of epilepsy and summarises the available data in favour of it. A Janus kinase (JAK) inhibitor called The medication upadacitinib is authorised Regarding the management of moderate- to-severe adult inflammatory arthritis (RA). Upadacitinib reduces inflammation and joint injury by inhibiting pro-inflammatory cytokine signalling by blocking JAK enzymes. Its side effects are tolerable and its safety profile is typically acceptable. This review looks at the data that is currently available to support the use of Upadacitinib in the therapy of RA, emphasising its safety, effectiveness, and potential as a treatment alternative for patients who don't respond well to traditional medications.
„A tanítás értékek vonzó módon történő felajánlása” – interjú Szabó László Tamás professzor úrral
Authors: Fekete Dorottya , Szűcs Tímea , Kiss Dávid , Papp Hunor , Ceglédi Tímea
Published: November 2024

Prof. dr. Szabó László Tamás, a rejtett tanterv metafora meghonosítója új alapokra helyezte az iskoláról való gondolkodást. A tanárképzésben betöltött szerepe miatt tanítványai gyakran a tanárok tanárának nevezik. Hazai és nemzetközi konferencia-előadások és publikációk sora fűződik nevéhez.
A következő interjúban azokról az életeseményekről, hatásokról kérdezzük, amelyek meghatározták tudományos karrierjét, és amelyek összefonódtak a hazai neveléstudományok történetével is. Az interjú a CHERD-Hungary Oktatáskutató Gyakornoki Programhoz kapcsolódó „Átkapcsolás, ahol a neveléstudományi kutató generációk találkoznak” című podcastsorozat1 negyedik beszélgetésének szerkesztett változata.
A sorozat három kutatógeneráció találkozását teszi lehetővé, akik az iskola, az oktatás és a nevelés kérdéseiről beszélgetnek. A felvételekre meghívtuk a neveléstudományok jelentős hazai letéteményeseit, olyan mestereket, akiktől sokat tanultunk.
Vendégünk továbbá egy-egy volt doktorhallgatójuk, aki jelenleg is aktív kutatómunkát folytat. Őket kérdezi egy-egy tanár szakos gyakornok hallgató a legfiatalabb kutatógeneráció képviseletében.
Az interjú során elhangzott kérdések a gyakornokprogram tagjai, a szervezők és kérdezők közös gondolkodása nyomán fogalmazódtak meg. A következőkben prof. dr. Szabó László Tamást a fiatal kutatógeneráció tagja, Fekete Dorottya, valamint professzor úr tanítványa, dr. Szűcs Tímea kérdezi.
Controllability of Impulsive Damped Fractional Order Systems Involving State Dependent Delay
Authors: G. Arthi , M. Vaanmathi
Published: November 2024

In this article, the concept of controllability on fractional order impulsive systems involving state dependent delay and damping behavior is analysed by utilizing Caputo fractional derivative. The main motivation is to derive the sufficient conditions for the controllability of the considered systems. Based on the Laplace transform and inverse Laplace transform, the solution of fractional-order dynamical systems are obtained. The results are established by utilizing basic ideas of fractional calculus, Mittag-Leffler function and Banach fixed point theorem. Finally, an application is provided to illustrate the derived result.
The Roles of Deep Eutectic Solvents in Batteries for Sustainable Energy Storage
Authors: M R RAMESH
Published: November 2024

The escalating demand for sustainable and efficient energy storage solutions has catalyzed the exploration of advanced materials and technologies in battery systems. Deep Eutectic Solvents (DES), a novel class of ionic liquids, have emerged as promising candidates due to their unique physicochemical properties, including low volatility, high thermal stability, and tunable solvation capabilities. This paper investigates the roles of DES in enhancing the performance and sustainability of batteries, particularly focusing on lithium-ion and sodium-ion technologies. DES-based electrolytes offer significant advantages, such as improved ionic conductivity and enhanced electrochemical stability, which are critical for the longevity and efficiency of battery systems. Furthermore, the eco-friendly nature of DES, derived from biodegradable and non-toxic components, aligns with the overarching goal of developing green and sustainable energy storage solutions. This study synthesizes recent advancements in DES research, evaluates their practical applications in current battery technologies, and discusses future directions for integrating DES in next-generation energy storage systems. The findings underscore the potential of DES to revolutionize battery technology, contributing to a sustainable energy future through enhanced battery performance and reduced environmental impact.
An overview of pathogenesis of metabolic dysfunction-associated steatotic liver disease
Authors: Habib Shahid , Johnson Andrew
Published: November 2024

Steatotic liver disease (SLD) has been known for a long time, but our understanding of this disease has remained poor until the past decade. Despite extensive research, our ability to comprehend the etiopathogenesis and natural course of SLD is far from the desired level of comprehension. This is required to develop a universally effective novel therapeutic agent. This review aims to concisely elaborate the conceptual approach and advancement in the understanding of global disease burden and etiopathogenic process, identifying the gaps and the pathophysiologic mechanism behind developing novel therapeutic agents. We searched two major databases, PubMed and Google Scholar, to identify publications related to the abovementioned topics. All publications, including original papers, reviews, and commentaries, were reviewed. Findings: Metabolic dysfunction-associated steatotic liver disease (MASLD) is not limited to obese individuals, rather, it may develop in any individual independent of weight. Visceral adiposity is strongly associated with MASLD and subsequent risks of cirrhosis, hepatocellular carcinoma, and cardiovascular disease. MASLD is associated with diabetes mellitus independent of underlying pathogenic mechanisms, and there is a bidirectional connection between MASLD and diabetes mellitus, making the situation quite challenging. Not all patients with MASLD exhibit atherogenic dyslipidemia and thus do not have a higher risk of cardiovascular disease. The overlap of these metabolic risk factors is not straightforward. There is a differential contribution of these risk factors based on age, gender, race, ethnicity, alcohol consumption, and microbiota composition. Poor dietary habits and lifestyle directly affect the microbiota, modulators, and mediators, thereby affecting the final biochemical processes leading to steatosis, steatohepatitis, fibrosis, and oncogenesis. In conclusion, MASLD is a complex and pathogenically heterogeneous disease with significant interpatient variation in the natural course and outcome. Understanding the precise mechanism of variability is the key gap and a limiting factor in the development of a novel therapeutic agent.
Melampaui Antropocentrism: Ekoteologi dan Etika Lingkungan dalam Dialog, Sebuah Pendekatan Interdisipliner Untuk Keberlanjutan dan Keadilan Ekologis
Authors: Sumule Linus
Published: November 2024

The current ecological issue has become a global challenge, one of the triggers of the current ecological issue is the human understanding that considers itself superior and anthropocentric. Responding to these fundamental problems needs to be addressed for the future sustainability of the earth. Interdisciplinary theology is present as an approach that bridges one or more disciplines to direct global issues that are being wrestled with. This research uses descriptive qualitative methods, collection and development of information through literature studies to answer the problem formulation being studied. The description contains ecological problems and interdisciplinary dialogues between eco-theology and environmental ethics to direct anthropocentric attitudes as the root of ecological problems. This research aims to provide new breakthroughs towards sustainability and ecological justice. The results of the study show that interdisciplinary theology provides a relevant and profound foundation for facing ecological challenges and shifting the human paradigm as a ruler of nature towards a wise and sustainable attitude.
Inkarnasi Allah sebagai Mahkota Sejati Ciptaan dalam Teologi Maximus the Confessor
Authors: Pranoto Minggus Minarto
Published: November 2024

Tulisan ini bertujuan untuk mengeksplorasi konsep inkarnasi Kristus sebagai mahkota sejati ciptaan dengan membangun argumentasinya didasarkan pada pengajaran Maximus tentang dyothelitism. Metode yang dipakai dalam artikel ini melalui studi literatur atau pustaka dengan menjelaskan pokok-pokok pemikiran teologi Maximus tentang relasi dua kehendak Yesus Kristus dalam beberapa karya tulisannya. Dyothelitism berbicara mengenai kesatuan kehendak Ilahi dan manusiawi secara harmonis di dalam diri Yesus Kristus. Kehendak manusiawi-Nya ditundukkan kepada kehendak Ilahi menjadikan inkarnasi Yesus Kristus ke dalam ciptaan sebagai mahkota sejati ciptaan. Ia contoh bagi ciptaan lainnya bagaimana seharusnya berelasi dan berpusat kepada Allah. Yesus Kristus menjadi perantara relasi kembali antara Allah dan ciptaan. Keselamatan dinyatakan melalui karya inkarnasi tersebut.
El control de constitucionalidad del estado de alarma. ¿Una oportunidad para desarrollar un correcta teoría general de los derechos fundamentales?
Authors: De la Quadra Tomás
Published: November 2024

El presente artículo tiene como propósito enunciar las líneas principales de una teoría general de los derechos fundamentales adecuada a nuestro texto constitucional y examinar los resultados que se habrían derivado de su aplicación si se hubiese utilizado para determinar la constitucionalidad de los confinamientos generales establecidos en el Real Decreto 463/2020, de 14 de marzo, que declaró el estado de alarma. Para ello examina críticamente la teoría general de los derechos fundamentales que subyace a la STC 148/2021 y que se funda en el principio de la intensidad de las restricciones y propone una teoría general alternativa que, se subraya, el propio Tribunal Constitucional habría utilizado en alguna jurisprudencia posterior a 2021 como la referida a la constitucionalidad de la vacunación recogida en la STC 38/2023, de 20 de abril.
Pengaruh Penerapan Metode Pembelajaran Ceramah dan Tanya Jawab Terhadap Aktivitas Belajar Siswa Jurusan Perkantoran di SMK Negeri 1 Ampana Kota
Authors: Rifai Moh. , Panigoro Meyko , Mahmud Melizubaida , Hasiru Roy , Ardiansyah Ardiansyah , Kasim Mamang
Published: November 2024

This research aims to investigate the Influence of Implementing the Lecture and Question-Answer Learning Methods on the Learning Activities of Office Administration Department Students at SMK Negeri 1 Ampana Kota. This research uses a quantitative approach alongside a descriptive-verification research method. The research data is primary data obtained through the distribution of questionnaires to the students of the Office Administration Department at SMK Negeri 1 Ampana Kota. The samples consist of 64 respondents, all students of the Office Administration Department at SMK Negeri 1 Ampana Kota. The data analysis technique used in this research is multiple linear regression and the SPSS program. The research results indicate that the lecture learning method's variable simultaneously influences the learning activities by 41.7%, with a positive regression coefficient. Similarly, the question-answer learning method variable influences learning activities by 26.8%, with a positive regression coefficient. The lecture and question-answer methods significantly influence the student learning activities, with a significance value 0.000. The partial test results demonstrate that lecture and question-answer methods positively influence student learning activities. The coefficient of determination, R Square, is 0.363 or 36.3%, indicating that both independent variables can explain the dependent variable (Icarfumgayitics). Other variables influence the remaining 63.7%.
Pengaruh Pengelolaan Dana Desa Terhadap Kesejahteraan Masyarakat Desa Tamboo Kecamatan Tilongkabila Kabupaten Bone Bolango
Authors: Buge Maulina Apriani , Bumulo Frahmawati , Mahmud Melizubaida , Hafid Radia , Sudirman Sudirman , Halid Risca Marsanti
Published: November 2024

This research employed a quantitative approach. The data were collected through observation, questionnaires, and documentation. The populations in this research were all Community welfare of Tamboo Village, Tilongkabila Subdistrict, Bone Bolango Regency, while the samples were 40 Community. The anaysis method employed Simple Linear Regression. The results indicated that the assignment method village fund management positive influence on the Community welfare of Tamboo Village, Tilongkabila Subdistrict, Bone Bolango Regency. From the calculation of the coefficient of determination, it indicated an R-square of 0,413, which meant that 41,3% of the variabiliti of community Welfare in Tamboo Village, Tilongkabila Subdistrict, Bone Bolango Regency is addressed by Village Fund Management Of the other hand, the remaining 58,7% is influenced by other variables not examined in the research.
Pengaruh Kedisiplinan Guru Terhadap Pendidikan Karakter Siswa Kelas XI di SMA Negeri 1 Tapa
Authors: Sefira Riska , Mahmud Melizubaida , Maruwae Abdurahim , Panigoro Meyko , Sudirman Sudirman , Gani Imam Prawiranegara
Published: November 2024

This research aims to observe the influence of teacher discipline on the character education of XI grade students at SMA Negeri 1 Tapa. This research uses a quantitative approach with a descrpyive method. The data in this research are primary data that is obtained by distributing quetionnaires to XI grade students at SMA Negeri 1 Tapa. The sample size is 65 respondents, consisting of all XI grade students. The data in this research are analyzed by using a simple linear regression alongside with the utilization of IBM SPSS 21.0 software. The results of this research show a positive and significant influence of teacher discipline on the character education of XI grade students at SMA Negeri 1 Tapa. The partial results indicate that the teacher discipline variable has a positive influence on the students character education, with an R Square determination coefficient value of 0.311 or 31,1%, which means that the independent variable could explain the dependent variable (Character education). In comparison, the remaining 69,9% is influenced by other variables that are not analyzed in this research.
Pengaruh Transparansi Dan Akuntabilitas Terhadap Pengelolaan Anggaran Dana Desa di Desa Piloliyanga Kecamatan Tilamuta Kabupaten Boalemo
Authors: Sulila Kevin , Hafid Radia , Sudirman Sudirman , Hasiru Roy , Taroreh Johni , Dama Maya Novrita
Published: November 2024

The aim of this research is to find out how much influence the aim of this research is to find out the effect of transparency and accountability on village fund budget management in Piloliyanga Village, Tilamuta District, Boalemo Regency. This research uses a quantitative approach with the method used in this research being a quantitative method. In this research the population was 1,101 heads of families, because the number of subjects was more than 100 people, the researcher took a sample of 50 heads of families.. Data collection techniques used in the research These are interviews, questionnaires, documentation and data analysis techniques in this research using multiple regression The research results show that there is a positive influence of transparency and accountability on village budget management in Piloliyanga Village, Tilamuta District, Boalemo Regency, which is positive and significant. The positive sign means that the better the value of the transparency and accountability variables, the better the budget management will be. village in Piloliyanga Village, Tilamuta District, Boalemo Regency, if there is a change in transparency and accountability there will be changes in the management of the village fund budget in Piloliyanga Village, Tilamuta District, Boalemo Regency in the same direction. The magnitude of the influence of transparency and accountability together on village fund budget management in Piloliyanga Village, Tilamuta District, South Boalemo Regency is 0.992 or 99.2% and the remaining 0.8% is determined by other factors outside the model which were not studied.
Analisis Kebiasaan cara belajar siswa berprestasi pada mata Pelajaran IPS Terpadu Kelas VII di SMP Negeri 2 Boalaang Mongondow Utara.
Authors: Hase Hase , Hafid Radia , Koniyo Rierind , Mahmud Melizubaida , Ardiansyah Ardiansyah , Polamolo Cristian , Dama Maya Novrita
Published: November 2024

This research aims to describe (1) the learning habits of high-achieving students in Integrated Social Science subject for Class VII of SMP Negeri 2 Bolaang Mongondow Utara, and (2) the factors influencing the learning habits of high- achieving students. The research method employs qualitative research, and utilizes observation, interviews, and documentation as data collection methods. The subjects of this research include one key informant and four supporting informants, consisting of the school principal of SMP Negeri 2 Bolaang Mongondow Utara, teachers of Integrated Social Science subject, and Class VII B students.  The results indicate that: (1) students have various learning habits; they are highly active during lessons, particularly enjoying reading and writing activities. They take notes when the teacher explains, prefer listening to the teacher, and actively participate in answering questions. High-achieving students effectively manage their study time. (2) Factors influencing students learning habits include physiological factor, where students' health conditions upon arriving at school affect their learning habits. Meanwhile, it also includes psychological factor en which can impact learning habits and social environment factor motivation