bluuebunny/crossref_metadata_2025 huggingface dataset:
Autophagic Dysfunction in Dementia: Scope for Development of Potential Remedies
Authors: Kumar Bhumika , Pandey Mukesh , Mishra Ashwini Kumar , Sharma Anjali , Fayaz Faizana , Pottoo Faheem Hyder
Published: December 2020

Dementia is a diverse category of chronic and progressive disorder, which is commonly
associated with a loss of memory, difficulty in judgment, impaired language, cognitive impairment,
and various other symptoms that affect a person’s daily routine life and social life. Dementia
affects about 50 million people around the globe. Dementia exists in varied forms and is associated
with various neurodegenerative disorders. Alzheimer's disease is the most common form, which accords
for about 60% of thecases. Abnormal agglomeration of proteins in the brain has been linked
to the pathogenesis of dementia. Autophagy is a necessary protein clearance mechanism, which is
dependent on lysosomes. It is a basic physiological process that performs the crucial function of
maintaining protein homeostasis within the cells. The autophagic dysfunction in dementia further
complicates the disease by hampering the degradation and removing abnormal pathogenic proteins.
In order to understand autophagic dysfunction, it is essential to know the genetics of autophagy as
well as the mutations This understanding at the genetic level helps definethe relationship between
dementia and autophagic dysfunction for developing the potential remedies for the treatment of dementia.
The Role of Nanoparticles as Nanocarriers for the Controlled Release of some Potential Existing Antiviral Drugs for SARS-CoV-2 Management: A Review
Authors: Ejeromedoghene Onome , Orege Joshua I. , Onwuka Justina U. , Adebule Philip A. , Ehianeta Teddy , Okonkwo Bright O. , Akinyeye Richard O.
Published: December 2020

Introduction:

The World Health Organization (WHO) has recently declared the outbreak
and spread of the new strain of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS--
CoV-2) a global pandemic. In this regard, a lot of scientific investigations and clinical trials on
some existing antiviral and antibiotic drugs have been ongoing to combat this menace.

Methods:

In the past, conventional drug therapy has shown irregular drug distribution, poor solubility,
and low permeability to target cells, organs, and tissues. However, Chloroquine, Hydroxychloroquine
Remdesivir, Lopinavir/Ritonavir, etc. have attracted several investigations in monotherapeutic
approaches and a combination of therapy have shown promising effects in reducing viral
loading in some SARS-CoV-2 infected patients. Nevertheless, the advent of nanomedicine has
triggered serious attention on drug-loaded nanoparticle as nanocarriers to deliver bioactive drug
molecules to target organs with increased circulation and controlled release. Therefore, the application
of nanoparticles as nanocarriers for the controlled release of antiviral drugs would improve the
ease of drug administration and care of patients admitted at various health care facilities worldwide.

Conclusion:

Owing to their small sizes, biocompatibility, and high encapsulation properties, nanoparticles
can be utilized as potential nanocarrier of antiviral drugs for the SARS-CoV-2 management
at a reduced cost with minimal side effect in the body system. In addition, some noticeable
concerns on the ongoing management of SARS-CoV-2 pandemic in developing nations have been
presented for concerted attention.
SARS-CoV-2: Origin, Pathogenesis and Therapeutic Interventions
Authors: Kundu Ipsita , Radharani NNV , Yadav Amit S , Patnaik Srinivas , Kundu Gopal C
Published: December 2020

:

In December 2019, a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly infected a large population in Wuhan city, Hubei province, China. Since then, it has been spread all over the world, causing a pandemic termed as Coronavirus Disease 2019 or COVID-19. It has infected over 32 million people and caused more than nine lakhs casualties worldwide to date. Till now, no specific drug or vaccine has been developed to prevent the spread of SARS-CoV-2. WHO has announced that maintaining personal hygiene and social distancing are the best available options against COVID-19. Various experimental and re-purposed drugs are being used as preventive and supportive therapy in different parts of the world. Comprehensive information about SARS-CoV-2 is required to develop therapeutic approaches for the prevention of COVID-19. In this article, we have comprehensively reviewed the origin, structure, and infection mechanism of SARS-CoV-2. We have also discussed the pathology of COVID-19, and various therapeutic interventions that are being used for drug development against COVID-19.
DETERMINANTS OF INTEREST IN USING TRAVEL VLOGS ON YOUTUBE AS A REFERENCE FOR TRAVELING
Authors:   Management and Business Program, Business School, Institut Pertanian Bogor, Rhendy Mamori Dore , Najib Mukhamad ,   Department of Management, Institut Pertanian Bogor, Maulana Agus ,   Business School, Institut Pertanian Bogor
Published: December 2020

This study aims to analyze the demographic characteristics, usage behavior, and things that have an impact on attracting viewers to watch and utilize travel vlogs on YouTube as a travel reference. respondents in this study 131 were selected based on criteria aged 18 years and over and had watched travel vlogs on youtube at least once in 3 months to find travel reference information. The analytical tool used in this study is the Structural Equation Model (SEM) using LISREL software. The results of this study are to find out things that affect interest in using travel vlogs on YouTube based on nine hypotheses. First, the popularity of the travel vlog variable does not affect the credibility of the perception variable. Variable perception of interest, attitude variables towards use have a significant effect. Second, the video characteristic variable influences the perception variable of credibility. Third, the video characteristic variable influences the perception of benefits. Fourth, the credibility perception variable influences perceived usefulness. Fifth, video characteristics influence attitudes towards use. Sixth, the credibility variable influences attitudes toward use. Seventh, perceived usefulness variables influence attitudes toward use. Eighth, the perception of video characteristics influences the use of interest. Ninth, Attitudes toward use affect the interest to use.
IMPROVED PERFORMANCE OF AGRICULTURAL EXTENSION AGENTS WITH INFRASTRUCTURAL FACILITIES AND TRAINING THROUGH JOB SATISFACTION
Authors:   Ministry of Agriculture, Agricultural Human Resources Extension and Development Agencies, Politeknik Pembangunan Pertanian Malang, Indonesia, Mumakinah Tri , Setiawan Margono ,   Faculty of Economics and Business, Universitas Brawijaya, Wirawan Irawanto Dodi ,   Faculty of Economics and Business, Universitas Brawijaya
Published: December 2020

The research aims to find out whether there is any significant correlation between infrastructural facilities, training, and performance of agricultural extension agents, mediated by job satisfaction in the Agricultural Extension Office in Malang Raya. This research used a qualitative method. The data was collected using a questionnaire, and the technique used in taking the sample was saturation sampling. The sample comprised all agricultural extension agents who were also civil servants, who had working experience of a minimum of one year, and worked at the district-level agricultural extension office in Malang. The total respondents were 145 people. The data analysis was conducted using Partial Least Square (PLS) Method by employing the 3.0 SmartPLS program. The research results showed that all the hypotheses put forward were corroborated except the one dealing with infrastructural facilities. Infrastructural facilities did not have a significant effect on job satisfaction because their availability had not been considerably capitalized on in carrying out the agricultural extension. Besides, it was found that job satisfaction did not mediate the influence of infrastructure on the performance of the extension agents. Recommendations for research in the future on similar topics may use an additional comparison between the satisfaction of expert and skilled agricultural extension agents, and the research method may be developed using qualitative methods.
PSYCHOLOGICAL CONTRACTS, INNOVATIVE WORK BEHAVIOR, AND KNOWLEDGE SHARING INTENTION: THE ROLE OF WORK ENGAGEMENT AND JOB RESOURCES
Authors:   Department of Management, Universitas Airlangga, Indonesia, Sulistiawan Jovi , Andyani Damaresty ,   Department of Management, Universitas Airlangga, Indonesia
Published: December 2020

This study examines the relationship between the psychological contract and innovative work behavior. The psychological contract consists of two types, relational and transactional. We tested whether work engagement mediates the relationship between those two types of psychological contract and innovative work behavior and knowledge sharing intention. Besides, we also tested the moderating effect of job resources whether to strengthen or weakened the relationship between psychological contract and work engagement. Using transformational directorate employees as our respondents because they are demanded to work innovatively. We employed Partial Least Square to test the hypotheses. Our findings will be discussed in the results and discussion section and followed by the implication of this study. This study contributes to understanding how and when the types of psychological contracts lead to innovative work behavior and knowledge sharing intention through work engagement.
Analysis of Platelet Function from Thromboelastography Examination in Patients with Single and Multiple Antiplatelet Therapy after Percutaneous Coronary Intervention in Dr. Saiful Anwar Malang
Authors: Widito Sasmojo , Hendrawan Dadang , Irawan Dedy
Published: December 2020

Each year, approximately 3 million people with coronary heart disease worldwide undergo percutaneous coronary intervention (PCI). Dual antiplatelet therapy (DAPT) with aspirin and P2Y12 inhibitors became the primary therapy for 6-12 months after PCI. DAPT can be continued > 12 months at a high risk of thrombosis. About 9-10% of patients with dual antiplatelet therapy still experience ischemia. The platelet function examination by thromboelastography (TEG). This research is an analytic observational study using a cross-sectional method. This study was conducted in Saiful Anwar General Hospital. Patients were divided into two groups: (1) on-single antiplatelet therapy; (2) on-dual antiplatelet therapy. The outcome measured result of the platelet function test was divided into standard, low platelet function, and platelet hypercoagulability. An analysis of the differences between single or multiple antiplatelet administration and the platelet function results was performed. There were 52 research subjects, each group of single and multiple antiplatelet therapies as many as 26 people, most of the subjects were male (82.6%) with a mean age of 57. The results of this study showed that there was no significant difference in the results of platelet function examinations between single and multiple antiplatelet therapies after 12 months of dual antiplatelet therapy.
Tamaño óptimo de las empresas de transporte colectivo que operan en el Área Metropolitana de Mendoza (Argentina), 2005-2012
Authors: García Schilardi María Emilia
Published: December 2020

Este trabajo avanza en el conocimiento de la estructura productiva del servicio de transporte colectivo en el Área Metropolitana de Mendoza (Argentina) durante la etapa previa a un cambio estructural del sistema de movilidad. Para ello, se estudia la existencia de economías de escala a través de la estimación de una función de costos de tipo translog. Se usan datos de panel para las empresas operadoras del servicio mediante buses, en el período 2005-2012. El resultado de este estudio evidencia un mercado que opera en el tramo de producción con deseconomías de escala, donde los costos promedios son crecientes, por lo que se recomienda que el mismo opere a través de un mayor número de empresas de menor tamaño.
El impulso a la formación del personal técnico para la industria mexicana: las aportaciones de Gonzalo Robles y Manuel Bravo Jiménez, 1945-1960
Authors: García Vázquez Xóchitl Ninel
Published: December 2020

El trabajo pretende reconstruir las aportaciones de Gonzalo Robles y Manuel Bravo Jiménez en la formación y capacitación de personal técnico durante los años de 1945 a 1960, período que se ubica en el proceso conocido como el “milagro mexicano”, donde el crecimiento se fundamentó en el desarrollo industrial. La dinámica del proceso industrial encontró varios obstáculos, entre ellos, la falta de personal técnico y la capacitación continua del ya existente. Ante ello, Robles y Bravo emprendieron, desde el Departamento de Investigaciones Industriales del Banco de México, una serie de investigaciones y estrategias tanto para conocer la estructura del personal técnico ocupado como las recomendaciones a emprender en el corto y mediano plazo como parte de una planeación económica nacional.
Editorial
Authors: López Rivera Edwin
Published: December 2020

Los artículos que componen esta nueva edición de la revista tiempo&economía abordan distintos aspectos del mundo del trabajo, la historia de las ideas económicas, el rol de los economistas en la política pública, la estructura económica del sector transporte y la salud pública en distintos países latinoamericanos. Este número también incluye un artículo sobre la evolución reciente de la epidemia de COVID-19 en Colombia y una entrevista sobre algunos aspectos económicos y políticos relacionados con la producción y distribución de vacunas para hacer frente a esta pandemia que azotó al mundo en 2019.
Facebook-Based Social Marketing to Reduce Smoking in Australia’s First Nations Communities: An Analysis of Reach, Shares, and Likes
Authors: Hefler Marita , Kerrigan Vicki , Grunseit Anne , Freeman Becky , Kite James , Thomas David P
Published: December 2020

Background

Facebook is widely used by Australia’s First Nations people and has significant potential to promote health. However, evidence-based guidelines for its use in health promotion are lacking. Smoking prevalence among Australia’s First Nations people is nearly 3 times higher than other Australians. Locally designed programs in Aboriginal Community Controlled Health Services (ACCHOs) to reduce smoking often use Facebook.

Objective

This study reports on an analysis of the reach and engagement of Facebook posts with smoking prevention and cessation messages posted by ACCHOs in the Northern Territory, Australia.

Methods

Each service posted tobacco control content at least weekly for approximately 6 months. Posts were coded for the following variables: service posted, tailored First Nations Australian content, local or nonlocally produced content, video or nonvideo, communication technique, and emotional appeal. The overall reach, shares, and reactions were calculated.

Results

Compared with posts developed by the health services, posts with content created by other sources had greater reach (adjusted incident rate ratio [IRR] 1.92, 95% CI 1.03-3.59). Similarly, reactions to posts (IRR 1.89, 95% CI 1.40-2.56) and shared posts (IRR 2.17, 95% CI 1.31-3.61) with content created by other sources also had more reactions, after controlling for reach, as did posts with local First Nations content compared with posts with no First Nations content (IRR 1.71, 95% CI 1.21-2.34).

Conclusions

Facebook posts with nonlocally produced content can be an important component of a social media campaign run by local health organizations. With the exception of nonlocally produced content, we did not find a definitive set of characteristics that were clearly associated with reach, shares, and reactions. Beyond reach, shares, and likes, further research is needed to understand the extent that social media content can influence health behavior.
Facebook-Based Social Marketing to Reduce Smoking in Australia’s First Nations Communities: An Analysis of Reach, Shares, and Likes (Preprint)
Authors: Hefler Marita , Kerrigan Vicki , Grunseit Anne , Freeman Becky , Kite James , Thomas David P
Published: December 2020

BACKGROUND

Facebook is widely used by Australia’s First Nations people and has significant potential to promote health. However, evidence-based guidelines for its use in health promotion are lacking. Smoking prevalence among Australia’s First Nations people is nearly 3 times higher than other Australians. Locally designed programs in Aboriginal Community Controlled Health Services (ACCHOs) to reduce smoking often use Facebook.

OBJECTIVE

This study reports on an analysis of the reach and engagement of Facebook posts with smoking prevention and cessation messages posted by ACCHOs in the Northern Territory, Australia.

METHODS

Each service posted tobacco control content at least weekly for approximately 6 months. Posts were coded for the following variables: service posted, tailored First Nations Australian content, local or nonlocally produced content, video or nonvideo, communication technique, and emotional appeal. The overall reach, shares, and reactions were calculated.

RESULTS

Compared with posts developed by the health services, posts with content created by other sources had greater reach (adjusted incident rate ratio [IRR] 1.92, 95% CI 1.03-3.59). Similarly, reactions to posts (IRR 1.89, 95% CI 1.40-2.56) and shared posts (IRR 2.17, 95% CI 1.31-3.61) with content created by other sources also had more reactions, after controlling for reach, as did posts with local First Nations content compared with posts with no First Nations content (IRR 1.71, 95% CI 1.21-2.34).

CONCLUSIONS

Facebook posts with nonlocally produced content can be an important component of a social media campaign run by local health organizations. With the exception of nonlocally produced content, we did not find a definitive set of characteristics that were clearly associated with reach, shares, and reactions. Beyond reach, shares, and likes, further research is needed to understand the extent that social media content can influence health behavior.
Editorial
Authors: Hall-Lew Lauren
Published: December 2020

Welcome to the second issue of Volume 6 of Lifespans & Styles: Undergraduate Papers in Sociolinguistics. I am sorry to say that this is the antepenultimate issue of the journal. We aim to publish Spring and Autumn issues of Volume 7, after which we will cease publication for the foreseeable future. Any potential author who wishes to make a submission for Volume 7 is invited to do so prior to the 1st of March 2021. After that, all submissions should be made instead to The Journal of the Undergraduate Linguistics Association of Britain, or any other journal that might be suitable for the topic of the paper. Any questions can be directed to me by email at the address below.
Exemplifying the Language Change of Jennifer Lopez
Authors: Bauernfeind Lea
Published: December 2020

This paper investigates American singer and actress Jennifer Lopez’s use of the sociolinguistic variables (ing), PRICE, and TRAP through a longitudinal study of readily available interviews over the course of 16 years. The study is an example of the same speaker of English showing lifespan change in one variable (TRAP), and age-grading in two others ((ing) and PRICE). The findings show that different variables can pattern differently, and that social context plays an important role in these linguistic developments.
Ciudad flâneuse: el andar entre la literatura y el arte acción
Authors: Cortés Fernández Orly C.
Published: December 2020

La imagen del flâneur surge a partir de paradigmas masculinos del siglo XIX. Es el concepto de un hombre burgués que recorre la ciudad libremente obteniendo placer y ejerciendo agencia con el andar. Esta definición sigue siendo considerada cuando se estudia la flânerie en las urbes del siglo XXI. No es tal el caso de la mujer urbana, ya que el papel de lo femenino se encuentra tradicionalmente adscrito al espacio privado, siendo la esfera pública considerada como un territorio esencialmente masculino. Es necesario estudiar las diferentes representaciones de las urbes para comprender cómo se proyecta el concepto de flâneuse, la mujer urbana que recorre la ciudad. A partir de un análisis comparatista, se busca mostrar cómo las representaciones artísticas y literarias —tal como la novela El huésped de Guadalupe Nettel y la pieza de arte acción Glorieta de los Insurgentes de Katnira Bello— son fundamentales para la configuración de la figura de la flâneuse en la Ciudad de México.
Apuntes para la etnohistoria Guane - Informe No. 1: La exogamia
Authors: Lucena Salmoral Manuel
Published: December 2020

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Sufijos despectivos en Inga
Authors: Levinsohn Stephen H.
Published: December 2020

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La cultura negra del Litoral Ecuatoriano y Colombiano: un modelo de adaptación étnica
Authors: Whitten Norman E. , De Friedemann Nina S.
Published: December 2020

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La fotografía como una técnica de la antropología visual
Authors: Duncan Ronald J. , Duncan Gloria S.
Published: December 2020

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Situación del Bogotá Chibcha
Authors: Broadbent Sylvia M.
Published: December 2020

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Mapping demographic processes: traditional and modern
Authors: Bazhukova N.V. , Balina T.A. , Chekmeneva L.Y.
Published: December 2020

Traditional and modern methods of mapping social and demographic processes are given in the article. The authors revealed the technique of multivariate analysis of the geodemographic situation, its territorial features, on the basis of which the typology of the Russian Federation constituent entities is carried out. Selecting five types of the country’s regions by similar signs of the geodemographic situation is justified; graphical models for the regions which are the most prominent examples of each type are presented. An integrated map reflecting the typology of the regions was created. The achievements and traditions of Perm State University Geography faculty’s cartographic school are particularly highlighted. The authors point out the necessity of using a variety of mapping and modeling methods. Not only mapping single quantitative demographic indicators is important but transition to a system of qualitative characteristics and indicators to create a geodemographic situation. Complex cartographic models will help to identify the local peculiarities of the development of geodemographic processes, show them in dynamics, reveal causal relationships, and justify regional socio-demographic policy as well.
Rescate y difusión del patrimonio cultural de Nandayure y Liberia por medio de la producción de dos largometrajes documentales
Authors: Castillo Valverde José Pablo
Published: December 2020

La riqueza histórica-cultural y en recursos naturales de las comunidades de Guanacaste ha convertido a esta provincia en sitio ideal para la producción documental educativa. El desarrollo de la promoción en redes sociales y dispositivos inteligentes ha hecho que dicho tipo de audiovisual tenga salida en las mismas comunidades. La inversión en promocionar tales producciones por medio de las redes permite que los habitantes de esa región puedan disfrutar de su propia cultura y sus orígenes al ver retratada su cotidianidad e historia en estos mismos audiovisuales. Por una parte, esta inversión debe ser parte de las estrategias de extensión de las universidades estatales que poseen oficinas dedicadas a la producción audiovisual educativa. Por otra parte, resulta también importante que el documental se convierta en una ventana para que dichas tradiciones sean vistas fuera de Costa Rica. Existen diferentes rutas para ello; pero una muy importante corresponde a las inscripciones y participaciones en concursos y festivales internacionales de cine. Un acercamiento de dicho tipo de productos y experiencias de trabajo que engloban los elementos mencionados, son los documentales de la UNED, «Las Tierras de la Princesa Nandayure» y «Una Fiesta en Liberia».
Puntos de encuentro entre el enfoque pedagógico de Paulo Freire y la Educación en Derechos Humanos
Authors: Núñez Méndez Allyson
Published: December 2020

La propuesta pedagógica de Paulo Freire genera los elementos tanto para una educación dirigida al cambio social como hacia el enfoque de la Educación en Derechos Humanos.  Este ensayo se propone como objetivos, primero, profundizar en los elementos que incluye el enfoque de Educación en Derechos Humanos; segundo, exponer los principales conceptos de la pedagogía de Paulo Freire y, tercero, demostrar que el enfoque de la Educación en Derechos Humanos es una de las formas más concretas de vinculación entre las tendencias en educación y la pedagogía de Paulo Freire. La Educación en Derechos Humanos se dirige a hacer de la persona un sujeto de derecho, con una gran capacidad de cuestionamiento crítico de la sociedad, que logra convertirse en un agente de cambio social, comprometido en el cumplimiento de los derechos humanos. Para lograr este camino, es necesario un docente que eduque para la crítica y para el cambio, por medio del diálogo.  La metodología empleada para la elaboración de este documento consistió en una revisión y un análisis profundo de los textos sobre el tema. Se concluyó que ambos enfoques educativos tienen coincidencias fundamentales sobre la esencia de la educación y el hecho educativo.
JOGANDO O JOGO TEATRAL NO LIVRO DO DIRETOR
Authors: Faria Alessandra Ancona de
Published: December 2020

O presente artigo pretende discutir o papel ocupado pelo sistema de jogos teatrais proposto por Viola Spolin, analisando de maneira detalhada o livro O jogo teatral no livro do diretor (SPOLIN, 1999), com a intenção de observar como esta publicação pode contribuir para o professor que trabalha com grupos de alunos da escola formal. O livro será analisado, estabelecendo-se um paralelo com as situações vivenciadas por um grupo de teatro, denominado “Pé Sujo”, em experimento proposto por mim como parte de minha pesquisa de mestrado no ano de 2002, na ECA/USP.
O EXERCÍCIO COMO CONSTRUÇÃO EDUCATIVA
Authors: Tancrede Onira de Ávila Pinheiro
Published: December 2020

A partir da relação Spolin – Piaget, o artigo relaciona o pensamento de Jean Piaget e a prática dos jogos improvisacionais de Viola Spolin ([1963]) no desenvolvimento do pensamento intuitivo num exemplo de prática escolar.
Os JOGOS TEATRAIS DE VIOLA SPOLIN COMO POSSIBILIDADE DE CONTAR HISTÓRIAS COM/NO CORPO PARA PROFESSORES
Authors: Duarte Valquíria
Published: December 2020

O presente artigo aborda a contação de histórias e suas possíveis relações com os jogos teatrais de Viola Spolin, tendo como eixo central a experiência que obtive por meio de oficinas de contação de histórias que ministrei e foram ofertadas para professores da Rede Municipal de Educação, em Goiânia, nos anos de 2017 e 2018.
UM JOGO ENTRE CAPOEIRA ANGOLA E ANTROPOLOGIA TEATRAL
Authors: Silva Renata de Lima , Falcão José Luiz Cirqueira
Published: December 2020

A Antropologia Teatral, um campo de estudo da presença física e mental do ser humano em situação de representação, conforme definição de Eugenio Barba, analisa um conjunto de princípios que dilatam a presença. Nesse artigo, esse campo, consolidado no teatro, é explorado como possibilidade de interpretação da prática da capoeira angola, uma manifestação cultural criada por africanos e seus descendentes no Brasil. Em uma provocação lúdica, com a utilização de uma personagem ficcional, construímos um jogo analítico com o propósito de extrapolar as noções de pré-expressividade e energia para além do corpo, levando em conta elementos da cultura, especialmente, da cultura negra.
[ID 33327] UMA ÚNICA OBSERVAÇÃO DA PRESSÃO PLANTAR REPRESENTA A MARCHA DE CRIANÇAS EM DIFERENTES DIAS?
Authors: De Medeiros Figueiredo Mariane , Silvelo Franco Pedro , Fraga Moro Cristiane , Souza da Rocha Emmanuel , Sosa Machado Alvaro , Pivetta Carpes Felipe
Published: December 2020

Objetivo: Determinar a variabilidade, a repetibilidade e as assimetrias da pressão plantar na marcha de crianças avaliadas em diferentes dias. Metodologia: Participaram deste estudo 12 crianças voluntárias (6 meninos) com idade média de 10,0±2,0 anos. Elas caminharam descalças em velocidade preferida ao longo de um trajeto de 9 m. A avaliação da marcha foi repetida em 4 dias não consecutivos de uma semana e a pressão plantar foi monitorada em cada um dos dias através de um baropodômetro. Os dados de pressão plantar foram comparados entre as pisadas em cada dia e entre os diferentes dias, considerando a pressão média e o pico de pressão para cada um dos pés. O índice de assimetria foi quantificado e comparado entre os dias. Resultados: As crianças tiveram um padrão consistente para pressão média e pico de pressão plantar. Os índices de assimetria observados foram similares entre os diferentes dias avaliados. Conclusão: A pressão média e o pico de pressão apresentaram valores consistentes em diferentes dias em que crianças são avaliadas, o que inclui similar assimetrias nos diferentes dias.
[ID 40779] RELAÇÃO ENTRE A HIPERTENSÃO ARTERIAL E A DOENÇA RENAL EM PORTADORES DE DIABETES TIPO 1
Authors: Ramos Alberto José Santos , Azevedo Erle Guimarães , Torres Maria Roseneide dos Santos , Oliveira Lucian Batista de , Macêdo Larissa Mirella Araújo de , Silva Diego Arley Gomes da , Coelho Andrea Lopes
Published: December 2020

Objetivo: Avaliar a associação entre a hipertensão arterial sistêmica (HAS) e a doença renal do diabetes (DRD) e a correlação dessas com outras complicações crônicas do diabetes, em portadores de diabetes mellitus tipo 1 (DM1), atendidos em ambulatório especializado. Metodologia: Estudo observacional, transversal e descritivo envolvendo pacientes com diagnóstico de DM1 bem estabelecido, atendidos em hospital universitário da Cidade de Campina Grande - PB. Foram avaliados dados sobre o tempo de doença e a idade atual, exames laboratoriais para avaliações glicêmica e lipídica e a presença de complicações crônicas. Resultados: A amostra foi de 346 pacientes, com média de idade de 23,0 ± 10,85 anos e o tempo médio de doença de 11,1 ± 7,27 anos. Constatou-se uma associação significativa (p < 0,001) entre as variáveis HAS e DRD (OR = 24,58) e de ambas com a retinopatia e a neuropatia diabética. Por meio das médias de hemoglobina glicada A1c, observou-se melhores níveis glicêmicos nos pacientes com HAS em comparação aos não hipertensos (p = 0,032) e naqueles com DRD em relação ao grupo sem acometimento renal (p = 0,042). Conclusão: A associação entre a HAS e a DRD em pacientes com DM1 mostrou-se bem estabelecida, reforçando a importância do rastreio de complicações e de satisfatórios controles glicêmicos e pressóricos para diminuir a morbimortalidade.
[ID 46404] INTERNAÇÕES POR DOENÇAS RELACIONADAS AO SANEAMENTO AMBIENTAL INADEQUADO (DRSAI) E O ACESSO AO SANEAMENTO AMBIENTAL EM MUNICÍPIOS DO SUL FLUMINENSE, 2010 - 2017
Authors: Paiva Roberta Fernanda da Paz de Souza
Published: December 2020

Objetivo: Buscou-se no estudo conhecer o perfil das doenças relacionadas ao saneamento ambiental inadequado nos municípios da Região Imediata Volta Redonda-Barra Mansa/RJ, no período de 2010 a 2017. Metodologia: Trata-se de um estudo descritivo, a partir de dados secundários para a população dos oito municípios que compõem a região, predominantemente industrial e que apresenta problemas de poluição hídrica e atmosférica. Resultados: Foi identificado um total de 5.496 internações por DRSAI. No município de Barra do Piraí foram identificadas: maior incidência das internações (63,1%), maior taxa média de internação (450,3/100.000 habitantes/ano), maior proporção de internações em relação ao total de internações no município (6,4%) e maior proporção de gastos (58% do total do grupo com as DRSAI). Na Região, a maioria dos casos de DRSAI foi de diarreia (64,6%), sendo a faixa etária mais acometida a de 0 a 4 anos (41,4%). Conclusão: Existem desigualdades entre os municípios em relação à cobertura por serviços de saneamento básico, afetando suas taxas médias de internação. O perfil indica que as internações e os gastos com as DRSAI se distribuem de maneira desigual entre os municípios analisados.
[ID 49743] AVALIAÇÃO DO COMPORTAMENTO DE RISCO PARA TRANSTORNOS ALIMENTARES E DISTÚRBIOS DE IMAGEM CORPORAL EM ESTUDANTES UNIVERSITÁRIAS
Authors: Nascimento de Melo Michelle Cristine , Ferreira de Oliveira Sara , Vasconcelos Leitão Moreira Patrícia , Lira Formiga Cavalcanti de Lima Rafaela
Published: December 2020

Objetivo: Avaliar a prevalência do comportamento de risco para transtornos alimentares e distúrbios de imagem corporal em estudantes universitárias do Curso de Nutrição da UFPB, bem como descrever o perfil socioeconômico e os hábitos gerais de vida das estudantes, verificando as possíveis associações entre essas variáveis e averiguar a associação entre os comportamentos de risco para transtornos alimentares e os distúrbios de imagem corporal entre as universitárias. Metodologia: Trata-se de um estudo tipo transversal. Foram utilizados os instrumentos Eating Attitudes Test (EAT-26) e o Body Shape Questionnaire (BSQ). Os dados foram analisados com o auxílio do programa SPSS, adotando-se o nível de significância de 5% (p
[ID 50412] PERFIL DA DISPENSAÇÃO DE MEDICAMENTOS CONTROLADOS PELO SISTEMA ÚNICO DE SAÚDE DE BOA VISTA DO INCRA – RS
Authors: Martins Prediger Jéssica , Morgan da Silva Bruna , De Souza Claudino Thiago , Woutheres Bortolotto Josiane , Bonfanti Azzolin Gabriela , Kessler Nunes Deuschle Viviane Cecilia
Published: December 2020

Objetivos: Avaliar quais os medicamentos controlados foram dispensados com maior frequência no Município de Boa Vista do Incra – RS. Metodologia: Trata-se de um estudo descritivo de caráter quantitativo de análise documental do banco de dados de dispensação da farmácia do município, nos meses de agosto e setembro de 2019. Resultados: Ao analisar as prescrições do referido período, verificou-se maior frequência de prescrição de quatro medicamentos: alprazolam (12,7%), citalopram (12,4%), amitripilina (13,7%) e sertralina (7,4%). Os dados encontrados demonstram maior frequência de prescrição de medicamentos psicoativos, corroborando dados de estudos acerca do assunto. Conclusões: Os dados revelaram uma elevada dispensação de medicamentos controlados, tendo em vista o número de habitantes no município estudado. Esses medicamentos apresentam a capacidade de provocar reações adversas, destacando-se a importância da atuação do profissional farmacêutico na promoção do uso racional de medicamentos, de forma a reduzir os riscos causados por essa classe medicamentosa.
Capture method affects survival estimates and subsequent interpretation of ecological covariates for a long-lived cervid
Authors: Brackel Katherine , Michel Eric , Gullikson Bailey , Jenks Jonathan , Jensen William
Published: December 2020

Understanding what variables affect ungulate neonate survival is
imperative to successful conservation and management of the species.
Predation is commonly cited as a cause-specific source of mortality and
ecological covariates often influence neonate survival. However,
variation in survival estimates related to capture methodology has been
documented with opportunistically captured neonates generally displaying
greater survival than those captured via aid of vaginal implant
transmitters (VITs), likely because of increased left truncation
observed in the opportunistically captured datasets. Our goal was to
assess if 3- and 6-month survival estimates varied by capture method
while simultaneously assessing if capture method affected model
selection and interpretation of ecological covariates for white-tailed
deer neonates captured from three study sites in North Dakota and South
Dakota, USA. We found survival varied by capture method for 3-month
neonate survival with opportunistically captured neonates displaying up
to 26% greater survival than their counterparts captured via VITs;
however, this relationship was not present for 6-month survival. We also
found model selection and subsequent interpretation of ecological
covariates varied when analyzing datasets comprised of neonates captured
via VITs, neonates captured opportunistically, and all neonates combined
regardless of capture method. When interpreting results from our VIT
only analysis for 3-month survival, we found survival varied by three
time intervals and was lowest in the first two weeks of life. Capture
method did not affect 6-month survival which was most influenced by
total precipitation occurring during 3 – 8 weeks of a neonate’s life
and percent canopy cover found at a neonate’s capture site. Our results
support previous research that capture method must be accounted for when
deriving survival estimates for ungulate neonates as it can impact
derived estimates and subsequent interpretation of results.
Naucni rad i rod - sinhrone i dijahrone perspektive
Authors: Prelic Mladena , Tomasevic Milan
Published: December 2020

nema
Fragments of autobiography: The concept of “flickering compassion” in Portraits of Women by Ksenija Atanasijevic
Authors: Basic Ivana
Published: December 2020

In our discussion we will explore how Ksenija Atanasijevic, while writing
about the poets and philosophers of ancient Greece, but also about Saint
Teresa of Avila and George Sand, expressed her own understanding of the
importance of women's scientific and artistic creativity, and also their
emancipation. By choice of women she will write about, as well as emphasis
on certain qualities of their personalities and their work, and the
philosophical concepts she supported, Ksenija Atanasijevic simultaneously
created her implicit imaginary philosophical "I" in Portraits of Women.
Therefore, the most precise genre definition of Portraits of Women would be
fragments of flickering compassion towards the personalities she is
describing, and compassion can be defined as a key characteristic of her
entire oeuvre and life - empathy was the basis of Ksenija Atanasijevic's
ethical philosophy and her social, pacifist and feminist engagement and at
the same time it was in her opinion the most important value of human life.
With this choice, Ksenija Atanasijevic also anticipated the stance of
contemporary feminism on the necessity of creating a female canon for
shaping a women's personal and creative identity.
Czechoslovak Republic and the formation of ethnographic science during the “First Republic” (1918-1938): Part II
Authors: Válka Miroslav
Published: December 2020

Our target is to assess how the Czech and the Slovak ethnography developed in
the period of the First Czechoslovak Republic (1918-1938), whether it
displayed international connotations, and to what extent it responded to the
common European development of this discipline. Research contacts between
Slavic ethnographers and geographers influenced one of the ethnographic
research lines in Czechoslovakia, and the evidence for this are the
application of Jovan Cvijic?s Anthropogeographic School and the application
of cultural and geographical research line in interwar Czechoslovakia?s
science. Between the world wars, Czechoslovak ethnographers paid attention
to Slovakia and to Carpathian Ruthenia, where forms of traditional folk
culture still actively lived on. Ethnography in the interwar Czechoslovakia
can be considered to be an important part of evolving European ethnology.
Unfortunately, this advancement was interrupted by political development
after World War II.
Ncor2/PPARα-dependent upregulation of MCUb in the type 2 diabetic heart impacts cardiac metabolic flexibility and function
Authors: Admin Ada , Cividini Federico , Scott Brian T , Suarez Jorge , Casteel Darren E. , Heinz Sven , Dai Anzhi , Diemer Tanja , Suarez Jorge A , Benner Christopher W , Ghassemian Majid , Dillmann Wolfgang H
Published: December 2020

The
contribution of altered mitochondrial Ca2+ handling to metabolic and
functional defects in type 2 diabetic (T2D) mouse hearts is not well
understood. Here, we show that the T2D heart is metabolically inflexible and
almost exclusively dependent on mitochondrial fatty acid oxidation as a
consequence of mitochondrial calcium uniporter complex (MCUC) inhibitory
subunit MCUb overexpression. Using a recombinant endonuclease-deficient Cas9
(dCas9)-based gene promoter pull-down approach coupled with mass spectrometry
we found that MCUb is upregulated in the T2D heart due to loss of glucose
homeostasis regulator nuclear receptor co-repressor 2 (Ncor2) repression, and
ChIP assays identified PPARα as a mediator of MCUb gene expression in T2D cardiomyocytes.
Upregulation of MCUb limits mitochondrial matrix Ca2+ uptake and impairs
mitochondrial energy production via glucose oxidation, by depressing Pyruvate
Dehydrogenase Complex (PDC) activity. Gene therapy displacement of endogenous
MCUb with a dominant-negative MCUb transgene (MCUbW246R/V251E) in vivo rescued T2D cardiomyocytes from
metabolic inflexibility, and stimulated cardiac contractile function and adrenergic
responsiveness by enhancing phospholamban (PLN) phosphorylation via Protein
Kinase A (PKA). We conclude that MCUb represents one newly-discovered molecular
effector at the interface of metabolism and cardiac function, and its repression
improves the outcome of the chronically-stressed diabetic heart.
Comments on dating and the periodization of the use of the burial ground in Domasław-Chrzanów, Wrocław district
Authors: Gediga Bogusław
Published: December 2020

The paper contains the comments of an archaeologist on the results of dating the Bronze and early Iron Age burial ground in Domasław, Wrocław district by the 14C method. Most of the dates obtained correlate well with previous archaeological dating to the Bronze and early Iron Age. There are, however, a few exceptions (namely, the stylistic characteristics of grave inventories) in which the established typological classification contrasts with the radiocarbon dates determined for these features and situates them much earlier, largely during the period of the Tumulus cultures in Polish territory in the II period of the Bronze Age in the periodization by O. Montelius/J. Kostrzewski and BC and BD in the southern periodization system. Similarly, several other assemblages from the youngest phase of the use of the burial ground from the HC period obtained much older dates.
En nordområdepolitikk om alt – eller ingenting?
Authors: Pedersen Torbjørn , Skagestad Odd Gunnar
Published: December 2020

I denne studien ser vi nærmere på hva som har skjedd med det som en gang var et utenriks- og sikkerhetspolitisk fokus, rettet mot våre umiddelbare nærområder i nord. Vi spør: I hvilken grad er dagens nordområdepolitikk egnet til å ivareta aktuelle sikkerhetspolitiske utfordringer i våre nordlige nærområder? Svaret denne gjennomgangen gir, er nedslående. Over flere år er norsk nordområdepolitikk blitt så utvannet og strukket at den i dag omhandler nær sagt alt. Dagens nordområdepolitikk er ispedd vel så mye regional- og næringspolitikk som utenriks- og sikkerhetspolitikk. Satsingen er i beste fall redusert til en slags samordningspolitikk, men uten entydige mål. Konfrontert med en rekke tunge sikkerhetspolitiske utfordringer i nord kan norske myndigheter fort oppleve at en altomfattende strategi bare blir en distraksjon. For en nordområdemelding om alt er gjerne også en nordområdemelding om ingenting.
Abstract in EnglishA Norwegian High North Policy about Everything – or Nothing?This study examines what happened to Norway’s nordområdepolitikk, or High North policy, erstwhile a targeted effort to address foreign and security policy challenges in Norway’s immediate neighboring northern areas. It finds that the current High North policy, after rounds of extensive revision, has become less suited to cope with Norway’s pressing security challenges in the said areas. Over the years, the Norwegian High North policy has become so diluted and all-including that it encompasses virtually anything and everything with a northern dimension, including regional development and industrial policies, to the neglect of foreign and security policy considerations. The High North initiatives have, at best, gradually transformed into a broad policy coordination effort, but without clear or prioritized policy objectives. Faced with a number of weighty security challenges in its immediate neighboring northern areas, Norway is currently guided by a policy that has metamorphosed into a distraction. A High North white paper about everything resembles a white paper about nothing.
Utforskende dialoger om to ungdomsromaner
Authors: Hennig Åsmund
Published: December 2020

Artikkelens formål er å undersøke hvordan elever initierer og utvikler sekvenser av utforskende dialog i elevstyrte litterære samtaler om to ungdomsromaner fra fritidskulturen. Bakgrunn for artikkelen er blant annet et ønske om bedre å forstå hvordan antatt interesse for og innlevelse i selvvalgte fritidstekster påvirker substansen i elevers litterære samtaler. Artikkelens empiriske grunnlag er analyser av lydopptak av litterære samtaler gjennomført av to grupper av elever på niende trinn, som del av en treårig studie av omfattende bruk av litterære samtaler på ungdomstrinnet. Det teoretiske grunnlaget består av transaksjonsteori (Jeffrey D. Wilhelm), teori om litterære samtaler og utforskende dialog (Harvey Daniels, Nancy Steineke, Neil Mercer, Douglas Barnes). Analysens sentrale funn er at utforskende dialoger her i hovedsak initieres av elevenes interesse for og innlevelse i de fiktive personenes mimetiske komponent og utvikles gjennom utveksling av perspektiver som også berører de fiktive personenes tematiske komponent. Elevenes skolering i litterære samtaler framstår også som en sentral medvirkende faktor.
English abstract
Exploratory talk about YA-fiction
The purpose of the article is to investigate how students initiate and develop sequences of exploratory talk in student-led literature circles about YA-fiction. The article seeks better understanding of how perceived interest in self-selected leisure texts affects the substance of students’ literature circles. The empirical basis for the article is analysis of audio recordings of literature circles conducted by two groups of students in grade 9, as part of a three-year study of extensive use of literature circles at secondary school. The theoretical basis consists of transaction theory (Jeffrey D. Wilhelm), theory of literature circles and exploratory talk (Harvey Daniels, Nancy Steineke, Neil Mercer, Douglas Barnes). The central findings of the analysis are that exploratory talk is mainly initiated by the pupils’ interest and immersion in the mimetic component of the fictional characters and is developed through the exchange of perspectives that also touch on the thematic component of the characters. Students’ education in literature circles also appears to be a key contributing factor.
The Impact of Good Corporate Governance Implementation on Firm Value
Authors: Ekasari Juendiny Chrisna , Kus Noegroho Yefta Andi
Published: December 2020

Many banking companies that offer shares on the Indonesia Stock Exchange, so it is very important for banking companies to pay attention to the value of their companies. This study aims to analyze the effect of the implementation of Good Corporate Governance on firm value through the existence of profitability. This study used a quantitative approach and secondary data collection, by testing the causal relationship of measurable research variables, namely examining the effect of GCG on firm value and profitability and positioning the profitability variable as an intervening variable. This study found that the direct relationship between GCG and profitability to firm value has an influence. Whereas, the results of this study also indicate the ineffective use of the proxied profitability of Return on Equity (ROE) as an intervening variable in the effect of GCG on firm value. This means that in banking companies listed on the IDX for the 2017-2019 period, GCG does not have an indirect effect on company value through profitability. Based on the results, if bank management pays more attention to the application of the principles of good governance (GCG), it will have an impact on increasing firm value.