bluuebunny/crossref_metadata_2025 huggingface dataset:
BIOPOLYMER-BASED FILM PREPARATION FOR POTENTIAL SMART FOOD PACKAGING MATERIAL APLLICATION
Authors: Barleany Dhena Ria , Sari D K , Lestari R S , Raharja Y , Gunawan A
Published: January 2024

Public interest in colorimetric films for food freshness monitoring has increased recently. In addition to extending the shelf life of packaged food products, packaging materials are also required to provide current information about the freshness of the food while ensuring food quality and safety. The current work aims to prepare smart biodegradable films based on biopolymer-containing color indicators to monitor the quality of Decapterus spp. The pH-sensing colorimetric film was developed from a chitosan biopolymer modified using polyvinyl alcohol (PVA) and glycerol, as well as methyl red, as an indicator of fish freshness. The effect of using PVA and stirring conditions (temperature and time) on film production was evaluated on its physical appearance, water vapor permeability, and mechanical properties. The results show that the use of PVA can increase the transparency of chitosan films. Incorporating PVA into the film results in brighter and clearer colors compared to films without PVA. The temperature used in the preparation of the film solution has an influence on the mechanical properties and the water vapor permeability. The increasing stirring temperature leads to the enhancement of Young's modulus and the barrier properties against water vapor and moisture, still concurrently impacting a decrease in the film's yield strength and strain. Additionally, the film also exhibits responsiveness to pH during fish spoilage, with a color change that occurs from pink to yellowish. This confirms that the pH-responsive film resulting from this research has great potential to be applied as a real-time indicator of fish freshness during storage.
TO THE MOON AND BACK: THE ADAPTATION OF MOON AS SYMBOL IN MOON KNIGHT'S COMIC TO TELEVISION SERIES ADAPTATION
Authors: Dimas Misbahul Munir  , Dian Leoni Andri  , Fadhilah Desy Handayani  , Gusti Faradila Indrayani  , Hadyan Rosyad  , Mariam Kusniah  , Tatik Apriliya  , Yanti Indah Suryani
Published: January 2024

Moon Knight is one of the best-selling series in Marvel Studios, and no studies discussed the moon's symbolism in the comic Moon Knight and the  TV series adaptations. This paper focuses on a shift in the meaning of the symbol from comics to TV series adaptations. In this research, the qualitative descriptive study is done to reveal whether the TV series adaptation of Moon Knight story faithfully reflects the moon symbolism in the comics. The research uses Hutcheon’s adaptation theory as background to analyze symbol adaptation, from the comic to TV series, and Eliade symbol theory to discuss the shift in the meaning of the symbols. The theory of Dissociative Identity Disorder from Kluft is used to analyze the three characters appear in the one body of the Moon Knight. Using Spradley's analysis method, we conclude that there are differences between the story from the Comic Moon Knight and its TV series adaptation. There were deficiencies that did not fully reflect the moon, and three symbols in the scene were unrelated to each other. The benefit of this research is to find out the significance of the differences in symbols in the adaptation of the Moon Knight series and to become reference material for future researchers who want to discuss the symbolization of the moon in the Moon Knight film.
NARRATIVE TECHNIQUE ANALYSIS OF SHERLOCK HOLMES AND AUGUSTE DUPIN IN A CROSSOVER FANFICTION PARACOSM
Authors: Rista Fathika Anggrela
Published: January 2024

Narrative technique refers to writers' methods and devices used to tell their stories. Understanding writers' processes and devices to convey their stories is crucial for analyzing and appreciating the arts. However, studying narrative techniques can be complex and requires close attention to detail. This study aims to explain what narrative techniques applied in the crossover fanfiction of Sherlock Holmes and Auguste Dupin to investigate how the narrative form generates impacts on losses and gains of the characterization of Sherlock Holmes and Auguste Dupin in references to their canons and to reveal why the characterization of Sherlock Holmes and Auguste Dupin in the crossover fanfiction are different from their canon. This research uses qualitative methods because the data are in the form of text taken from crossover fanfiction Paracosm (2016) by BiancaAparo. The data are analyzed using Gerald Genette’s narrative techniques. The result of this study showed that the dominant data of narrative techniques applied in Paracosm is narrative mood, which loses their characterization. Narrative mood relates to the position or position of the author, narrator, and characters in a story. That is why the narrative mood is mainly found along with the research objects, the main characters in this fanfiction, Sherlock Holmes and Auguste Dupin. It shows that the two characters have an impact, causing losses of their characteristic. Yet, that does not prevent any gain of the characteristic based on the characters in the original work. Thus, fanfiction can be different from the canon because it is written by different author with different biographical and social elements.
Advancements in Planetary Unstructured Equivalent Source Inversion and Current Circulation Modeling Technology for Earth's Magnetic Field
Authors: Zuo Boxin , Wang Lizhe , Hu Xiangyun , Cai Yi , Kass M. Andy
Published: January 2024

This study presents a novel approach to modeling the Earth’s geomagnetic
field, which originates from electric currents approximately 2,900 km
beneath the surface, crucial for understanding planetary dynamics. We
introduce a method for inverting a planetary-scale equivalent
magnetization source and develop a 3-D equivalent electric current
circulation model from this source, enhancing understanding of these
deep currents. This research signifies the first use of unstructured
tetrahedral magnetization inversion technology for planet-scale magnetic
data interpretation and equivalent source model construction. Validated
through a synthetic case study, the method is applied to the
International Geomagnetic Reference Field (IGRF) and SWARM satellite
datasets, comprising 35,768 magnetic vectors from two orbital altitudes.
Employing various mesh configurations, we construct and compare detailed
current source models from these datasets. The effectiveness of our
equivalent current sources is confirmed by comparison with dynamo
research findings, demonstrating significant advancements in geomagnetic
field modeling, particularly in interpretability, and providing novel
insights into Earth’s magnetic phenomena.
Stable Middle Miocene seawater isotopes in the eastern North Atlantic Ocean
Authors: Hättig Katrin , Schouten Stefan , Louwye Stephen , Meer Marcel van der
Published: January 2024

The Middle Miocene is characterized by a long-term increase in the
oxygen isotopes of benthic foraminifera
(δO). However, it is unclear
to what extent this increase reflects changes in seawater isotopes or
deep water temperature. We present a high-resolution alkenone hydrogen
isotope (δH) record of the middle
Miocene from a core taken at the upper slope edge (about 409 m water
depth) of the Porcupine Basin continental margin in the eastern North
Atlantic Ocean, Site U1318 of the Integrated Ocean Drilling Program. The
δH values vary between -174 to
-200‰ with an average of -191 ±5‰, similar to modern open-ocean values.
Importantly, it does not show a long-term increase in surface seawater
isotopes (δH) during the Middle
Miocene Climate Transition. Indeed, when
δO is corrected for
subsurface temperature, the average bottom seawater oxygen isotopes of
0.9 ±0.2‰ also show no significant increase. When the latter record is
translated into hydrogen isotopes of bottom seawater using the modern
open-ocean waterline, it shows an average value of 5.8 ±1.5‰ similar to
the δH of 5.2 ±3.1‰ derived from
δH suggesting relatively small
difference between bottom and surface waters. Our results suggest a
stable global surface seawater isotope evolution during the Middle
Miocene, coupled with a long-term decrease in bottom water temperature.
Variation of molecular ions in the inner magnetosphere observed by the Arase satellite
Authors: Nagatani Akari , Miyoshi Yoshizumi , Asamura Kazushi , Kistler Lynn M. , Nakamura Satoko , Seki Kanako , Ogawa Yasunobu , Shinohara Iku
Published: January 2024

We analyzed time-of-flight (TOF) data from the Arase satellite to
investigate temporal variations of O2+, NO+, and N2+ at 19.2 keV/q in
the inner magnetosphere for 6.5 years from the solar declining to rising
phases. Molecular ion counts were estimated by subtracting the
background contamination of oxygen counts. While the number of clear
molecular events was small, the estimated molecular ion counts exhibited
good correlation with the solar wind dynamic pressure and SYM-H index.
Long-term variations of molecular ions were different from that of
oxygen ions. Additionally, we discuss the importance of the solar wind
dynamic pressure in causing the escape of molecular ions into the
magnetosphere through an increase in the convection electric field,
which causes different evolutions of oxygen ions and molecular ions.
Quantifying the Impact of Internal Variability on the CESM2 Control Algorithm for Stratospheric Aerosol Injection
Authors: Connolly Charlotte J , Prewett Emily M , Barnes Elizabeth A. , Hurrell James Wilson
Published: January 2024

Earth system models are a powerful tool to simulate the response to
hypothetical climate intervention strategies, such as stratospheric
aerosol injection (SAI). Recent simulations of SAI implement tools from
control theory, called “controllers”, to determine the quantity of
aerosol to inject into the stratosphere to reach or maintain specified
global temperature targets, such as limiting global warming to
1.5\textdegree C above pre-industrial temperatures. This
work explores how internal (unforced) climate variability can impact
controller-determined injection amounts using the Assessing Responses
and Impacts of Solar climate intervention on the Earth system with
Stratospheric Aerosol Injection (ARISE-SAI) simulations. Since the
ARISE-SAI controller determines injection amounts by comparing global
annual-mean surface temperature to predetermined temperature targets,
internal variability that impacts temperature can impact the total
injection amount as well. Using an offline version of the ARISE-SAI
controller and data from CESM2 earth system model simulations, we
quantify how internal climate variability and volcanic eruptions impact
injection amounts. While idealized, this approach allows for the
investigation of a large variety of climate states without additional
simulations and can be used to attribute controller sensitivities to
specific modes of internal variability.
DNA methylation-based assessment of cell composition in human pancreas and islets
Authors: Drawshy Zeina , Neiman Daniel , Fridlich Ori , Peretz Ayelet , Magenheim Judith , V Rozo Andrea , M Doliba Nicolai , A Stoffers Doris , H Kaestner Klaus , A Schatz Desmond , Wasserfall Clive , Campbell-Thompson Martha , Shapiro James , Kaplan Tommy , Shemer Ruth , Glaser Benjamin , Klochendler Agnes , Dor Yuval
Published: January 2024

Assessment of pancreas cell type composition is crucial to the understanding of the genesis of diabetes. Current approaches use immunodetection of protein markers, for example insulin as a marker of beta-cells. A major limitation of these methods is that protein content varies in physiological and pathological conditions, complicating the extrapolation to actual cell number. Here we demonstrate the use of cell type-specific DNA methylation markers for determining the fraction of specific cell types in human islet and pancreas specimens. We identified genomic loci that are uniquely demethylated in specific pancreatic cell types and applied targeted PCR to assess the methylation status of these loci in tissue samples, enabling inference of cell type composition. In islet preparations, normalization of insulin secretion to beta-cell DNA revealed similar beta-cell function in pre-T1D, T1D and T2D , which was significantly lower than in non-diabetic donors. In histological pancreas specimens from recent-onset T1D this assay showed beta-cell fraction within the normal range, suggesting a significant contribution of beta-cell dysfunction. In T2D pancreata we observed increased alpha-cell fraction and normal beta-cell fraction. Methylation-based analysis provides an accurate molecular alternative to immune detection of cell types in the human pancreas, with utility in the interpretation of insulin secretion assays and the assessment of pancreas cell composition in health and disease.
Evaluation of Cytological and Morphological Characteristics of S. aethiopicum Var “Anara Adazi” Found in Anambra State
Authors: CV Ilodibia
Published: January 2024

Solanum aethiopicum L. var “anara Adazi” is a yearly shrub in the family Solanaceae. It is produced for its edible fruits which are cooked and eaten as a vegetable. In our locality, S. aethiopicum var “anara Adazi” is both nutritionally and medicinally important. But its morphological and basic mitotic and meiotic chromosomal counts are yet to be evaluated. This study was carried out to investigate the mitotic and meiotic chromosome counts and the external features of S. aethiopicum with regards to cytological and morphological characteristics. Mitotic and meiotic cytological study was done using the root tip and flower buds squash techniques, respectively. Morphological study was done by optical observations and use of hand lens to magnify those parts which are quite tiny. The Cytological result revealed the plant to be diploid with mitotic counts of 2n=2x=24 and meiotic chromosome number as n=12. The morphological result revealed among others the habit of the plant to be a fairly woody annual in the temperate or perennial shrub in other regions, leaves are alternately arranged, pinnately veined, and a racemose flower. Cytological studies indicated that the plant’s degree of fertility and viability is high and could be employed in hybridization programme. The overall data are valuable for taxonomic characterization and identification of the plant species in the genus.
The Bath of the Deities: Considerations on the Sacred in a Hare Krishna Ritual
Authors: Oliveira Silva Victor Hugo
Published: January 2024

Starting from a reflection on the concept of the sacred, in this article I intend to address how a spiritual practice of Indian origin, the so-called bath of the Deities, can contribute to this debate. For this purpose, an ethnographic description of the event in question will be taken as an object, in order to provoke a debate with authors such as Emile Durkheim, Arnold Van Gennep and others who focus more specifically on Hinduism, such as Gavin Flood and Lúcio Valera.
Class Formation in Post 2018 Ethiopia; A Commentary
Authors: Tolera Megersa
Published: January 2024

This commentary aims to explore the dynamics of class formation in post-2018 Ethiopia, with a focus on the emergence of a new middle class, the opportunities and challenges it presents, and its implications for the country’s economic and social development. The study employs a qualitative approach, drawing on existing literature, policy documents, and interviews with experts in the field. The findings indicates that the emergence of a new middle class in post-2018 Ethiopia is a complex and multifaceted process, influenced by a range of political, economic, and social factors. While the growth of this class presents opportunities for economic growth and social mobility, it also exacerbates existing inequalities and poses challenges to social cohesion. The study concludes that a comprehensive and inclusive approach to economic and social development is necessary to address these challenges. This includes policies that address income inequality, promote regional unity, invest in education and job creation, and support vulnerable populations. The government must also engage in collaborative and inclusive policymaking to ensure that the benefits of economic growth are shared more equitably across society. Based on these findings, the study recommends that policymakers in Ethiopia take a holistic approach to class formation, recognizing the diverse and evolving nature of the country’s social and economic landscape. By doing so, they can promote greater stability and prosperity for all Ethiopians, and ensure that the benefits of economic growth are shared more equitably.
Eve or “Evolution”? : The Question of the Creation of Adam and Eve as the First Humans versus the Theory that Humankind “Evolved” (Self-Changed) Over Millions of Years
Authors: T Choice Eloise
Published: January 2024

Inherent in the Creation (“Intelligent Design”) versus the Theory of Evolution (“natural selection”) War, is the scientific belief in the millennia-long “evolution” of humankind, versus the Christian belief in the creation of the Biblical Adam and Eve circa 7,700 B.C. This paper proposes that there is no such thing as an “evolution” of Earth’s life forms, with “evolution” being defined as self-adaptations over time to specific environments with physical modifications. Over the course of millions of years, God created then, re-designed all Earth’s life forms in successive stages, which accounts for the non-linear progression of said forms and particularly of humanoids. Integrating Mitochondria DNA and archaeological evidence with Judeo-Christian, Muslim and extra-Biblical texts, shows that after God created then re-designed pre-Adamic humans, He created the Biblical Adam and Eve circa 9,700 years ago during the Mesolithic Period as prototypes for present-day man. Moreover, archaeological evidence, plus Judeo-Christian and extra-Biblical texts, suggest that Eve and Adam co-existed with Homo sapiens during the Mesolithic/ Neolithic Periods.
Impact of Dietary Choices on Immune System Functionality
Authors: BAR* Hassan
Published: January 2024

In our daily lives, we are invariably exposed to a diverse spectrum of bacteria, some posing potential hazards. The human immune system, an extraordinary assemblage of interconnected organs and cells, serves as our defense against these harmful bacteria, viruses, and various diseases. A critical function of the immune system is to combat harmful entities such as viruses, germs, and parasites. Essential to the optimal functioning of the immune system is the consumption of a diet rich in both macroand micronutrients. Embracing a healthy lifestyle, which includes increasing the intake of water, essential minerals (notably magnesium and zinc), micronutrients, herbs, and foods rich in vitamins C, D, and E, is fundamental to maintaining health and preventing infections. This article conducts a thorough analysis of common foods renowned for their immune-enhancing properties. It highlights the vital role of a nutritious, balanced diet in promoting effective immune function and discusses the impact of dietary habits on immunological responses. The article provides an in-depth examination of numerous popular foods, scrutinized for their ability to strengthen the immune system. This category encompasses foods derived from animals, as well as fruits, vegetables, and whole grains. We explore various food groups, focusing on the nutrients and bioactive compounds they contain, and how these contribute to immune system support. Particular emphasis is placed on the consumption of foods like milk, eggs, fruits, leafy greens, and spices such as turmeric, garlic, and onion, all rich in beneficial compounds. These compounds have the potential to activate and inhibit immune cells, as well as to interfere with various biological pathways, thereby enhancing immune responses and defense mechanisms. The development of this article involved an extensive search and critical review of relevant literature, primarily sourced from online resources, ensuring a comprehensive and scientifically grounded exploration of diet's role in bolstering the immune system.
Comprehensive Insights into ModRNA Vaccines: Persistent PP-Spike Recombinant Protein, Hyperimmune/Inflammatory Reactions, Thrombotic Vasculopathy, Chronic Organ Complications and Excess Deaths
Authors: Castrillo R* Palacios
Published: January 2024

A recent study revealed a persistent presence of the PP-Spike recombinant protein in 50% of individuals who received ModRNA injections, contrasting with unvaccinated controls, whether SARSCoV-2 infected or not, up to 187 days post-injection. The implications of these findings are discussed in the context of PP-Spike recombinant protein-induced hyperimmune/ inflammatory reactions and thrombotic vasculitis as mechanisms to elucidate the serious side effects, long-term organ complications, and excess deaths observed after administering Covid ModRNA products. These results underscore the urgent need for a comprehensive reassessment of the risk-benefit profile of ModRNA injections, including an immediate halt in their use for any person, and a renewed emphasis on understanding and addressing their long-term effects on human health.
Service-Based Medical Platform for Personal Health Monitoring
Authors: AI* Petrenko
Published: January 2024

Previous developments of medical mobile applications usually were monolithic ones, designed for a fixed HW infrastructure. The whole application has to be developed and deployed in one piece and the entire tier has to be retested and redeployed when something is changed. Hundreds of applications for smart phones with various operating systems have been created by different providers. We are mostly the first who start to investigate advantages of service-oriented architecture in mobile medicine. This paper is a generalization of the author's publications on the possible usage of the service-oriented computing paradigm (SOC) for building a medical services platform which allows unifying the development of applications for patients, doctors and the central server by orchestrating and composing web services from a common cloud repository. Due to this approach the created applications can be adapted to the particular patient, his disease and the plan of his treatment at home.
Protein Adsorption from Aqueous Solution by Supports
Authors: Sadraei Razieh
Published: January 2024

Enzymes are the biocatalysts of the living world, but their properties render them also exploitable in many applications that range from industrial catalysis to therapeutics, including synthetic and pharmaceutical chemistry, wastewater bioremediation, fabrication of high performance biosensors, among others. The use of enzymes, however, is limited by their recovery since this aspect plays a significant role in the evaluation of the cost of the biocatalytic processes, therefore several methods have been proposed for their immobilization on stable supports. This study investigates the possibility of using different phases of nano-alumina for enzyme capture and reuse.
The Ergonomics as a Facilitator for the Inclusion of Disabled Workers in Institutional Spaces
Authors: Borges Paraizo Claudia
Published: January 2024

Mentioned in the preface of the Convention on the Rights of Persons with Disabilities, we have understood and taken the concept of “disability” as an evolving concept as a result from the interaction between people with disabilities and attitudinal and environmental barriers that prevent them from exercising their autonomy in full.
Next Generation Sequencing: A Step toward Unraveling of Biosynthetic Pathways in Plants
Authors: Awasthi Praveen
Published: January 2024

Plant science is largely driven by DNA sequence data, which has been fundamentally changed in last decade due to the development and emergence of next-generation sequencing (NGS) technologies. NGS has played a vital role in the advancement of plant genomics, which has opened the opportunities for genetic improvement of crop plants and identification of biosynthetic pathways of important pharmaceutical biomolecules (tanshinones, forskolin, artemisinin etc.).
Segmentation of Electrocardiograms as an Example of Experimental Curves Processing Using Variable Resolution
Authors: Kalmykov Vladimir
Published: January 2024

A new segmentation method of signals on the example of electrocardiograms is proposed. Unlike other known methods, for example, the canny method, a priori data on interference and / or a signal (image) is not used. Segmentation of signals and halftone images distorted by interference is one of the oldest problems in computer vision. But human vision solves this task almost independently of our consciousness. It was discovered for visual neurons, that sizes of receptive fields' excitatory zones change during visual act, which eventually mean dynamical changes in visual system's resolution i.e. coarse-to-fine phenomenon in living organism. We assumed that "coarse-to-fine" phenomenon, i.e. several different resolutions, is used in human vision to segment images. A "coarse-to-fine" algorithm for segmentation of experimental graphs was developed. The main difference of algorithm mentioned above from others is that decision is made taking into account all partial solutions for all resolutions being used. This ensures stability of final global solution. The algorithm verification results are presented. It is expected that the method can naturally be expanded to segmentation of halftone images.
Importance of Artificial Intelligence & Biophotonic Techniques in Point of Care Diagnostocs of Hiv/Aids
Authors: Dubey Anubha
Published: January 2024

Bio photonics is a branch of science dealing with the interaction of light in biological substances such as tissues and cells at scales ranging from microns to the nano-level. This quality of biophotonics leads to understand hidden knowledge of cell-cell interaction, cell-tissue interaction and so-on. It needs to be more explore in HIV/AIDS for treatment and diagnosis. Artificial Intelligence based predictive models help to develop such chips which are cost effective, ready to use and require less time for diagnosis. These photonics based methods also need to develop therapeutics for HIV.
The Use Case of Artificial Intelligence in Improving Health
Authors: Dubey Anubha
Published: January 2024

Artificial intelligence (AI) is areas of computer sciences that emphasizes the creation of intelligent machines that work and react like humans. There are some of the activities computers with artificial intelligence can do i.e. Speech recognition, Learning, Planning, Problem solving, Perception, Ability to manipulate and move objects.
Productive Performance, Caeca Microbial Population and Immune-Modulatory Activity of Broiler Chicks Fed Different Levels Sida Acuta Leaf Extract in Replacement of Antibiotics
Authors: MD Shittu
Published: January 2024

The aim of the present study was to examine the productive performance, caeca microbial population and immune-modulatory activity of broiler chicks fed different levels Sida acuta leaf extract (SAL) in replacement of antibiotics. A total of 375 one-day old broiler chicks (Ross 307) were allotted to five treatments with five replicates consisting of 15 birds each in a completely randomized design. The experiment lasted for 56 days during which feed and water were given ad libitum. Basal diet was formulated to meet the nutrient requirements for birds according to NRC (1994) and all other management practices were strictly observed. Birds in treatment 1 (T1) were fed basal diet with 0 % administration of ciprofloxacin, T2 were fed a basal diet plus administration of 0.2ml of ciprofloxacin/liter of water while T3, T4 and T5 were fed Sida acuta leaf extract (SAL) at 20ml, 40ml and 60 ml per liter of water to replace ciprofloxacin as antibiotics. Result obtained revealed that weight gain, average daily weight gain (ADWG) and feed: gain ratio were significantly (P˂0.05) influenced among the treatments. Highest mortality was recorded in T1 (15.1 %) followed by T2 (10.0 %) none were recorded in the other treatments (P˂0.05). Average daily feed and water intake were not significantly (P˃0.05) different among the treatments. Antibody titres against Newcastle and Gumbro disease were significantly (P˂0.05) different among the treatments. Birds fed SAL had the highest values of antibodies making them resistant against diseases. Similarly, caecal microbial population revealed that E.coli population decreases in T3, T4 and T5 as the level of SAL increases among the treatments. However, lactobacilli populations were highest in T3, T4 and T5, intermediate in T2 and lowest in T1 ((P˂0.05). It was concluded that SAL is loaded with several bioactive compounds can be used to bridge the gap between food safety and livestock production and its oral administration at 20 ml/ liter of water had no deleterious effect on the performance and health status of broiler chicks.
Inter Carbon Distance from Nearest Atom Reveal Presence of Various Functional Units in Proteins
Authors: Rajasekaran Ekambaram
Published: January 2024

Carbon plays an important role bio-molecular structure and function. Carbon distribution is responsible for bio-molecular association. This carbon distribution in proteins has been part of our activities in the last 15 years. It has been carried out from sequence to structure level. It required hydrogen atom added to the structure for analysis and all. Here the similar observations from carbon coordinates obtained from X-ray structure are reported. The carbon distance from nearest carbon is focus of this work. The distance is computed for a set of carbon atoms present in a particular spherical dia. The distances are grouped based on its values which are ranging from 2.1 to 3.1with group interval of 0.1. This distance distributed over different groups are analysed for presence of active site, order, disorder, carbon-rich and poor-carbon regions. The results are able to locate these sites as well as identify amino acids that need to be mutated for stability and function. The results are in agreement with other predictions obtained from sequence and all atom analysis. This distance distribution analysis gives guidance on how important the carbon distribution in these biological systems and to deal further with liveable material in the future to come globally or universally
Proteomics Loans in Kinetoplastids during the Last Decade
Authors: Duschak Vilma Gladys
Published: January 2024

Kinetoplastida are flagellated protists characterized by the presence of an organelle called kinetoplast. This characteristic feature is an unusual large DNA- containing granule located within the single mitochondrion, associated with the basal body of the cell’s flagellum. It contains many copies of the mitochondrial genome. These organisms are commonly referred to as “kinetoplastids”. This group comprises parasites responsible for serious diseases in humans as well as other animals. Among kinetoplastids, the family of Trypanosomatids, is notable as it includes some organisms which are exclusively parasitic such as Trypanosoma and Leishmania.
Effect of Dietary Inclusion Levels of Moringa Olerifera Oil on the Growth Performance and Nutrient Retention of Broiler Starter Chicks
Authors: OCP Agubosi
Published: January 2024

An experiment was carried out to examine the effect of dietary inclusion of Moringa oleifera oil (MOO) on the growth performance and nutrient retention of broiler chicks. A total of 180-day- old broiler chicks (Arbor acre) of mixed sex were randomly allotted into six dietary treatments of 30 birds per treatment; each treatment was further divided into 3 replicates consisting of 10 birds each in a completely randomized design. Basal diet was formulated to meet the nutritional requirements of broiler chicks, feed and clean water were given ad libitum throughout the experiment which lasted for 28 days. Birds in treatment 1 (T1) were fed basal diet with Oxytetracycline at 1.5g/kg feed while birds in T2, T3, T4, T5 and T6 were fed basal diet mixed with MOO at 0.1, 0.2, 0.3, 0.4 and 0.5 mL/kg feed respectively. Results on gas chromatography- mass spectrometry (GC-MS) revealed the presence of 17 bioactive compounds which accounted for 70.72 %. The major compounds identified in MOO are: β-caryphyllene (19.02 %), β-myrcene (16.08 %), carvenone (10.11 %) and α-cubebene (7.11 %) respectively. Data on average daily weight gain, average daily feed intake and feed conversion ratio were not significantly (P˂0.05) different among the treatments. Highest mortality was recorded among birds in T1 (0.33 %) followed by T2 (0.01 %) none was recorded in the other treatments (P˂0.05). Results on nutrient retention (dry matter, crude protein, crude fiber, ether extracts and nitrogen free extracts) were influenced by the dietary inclusion of MOO. It can be concluded that MOO could be fed to broilers up to 0.5 mL per kg feed without causing any negative effect on the performance of birds.
Heteroclite and Turgid-Atypical Adenomatous Hyperplasia Lung
Authors: Bajaj Anubha
Published: January 2024

Atypical adenomatous hyperplasia emerges as a miniature, localized proliferation of atypical pneumocytes which layer intact alveolar spaces. Atypical adenomatous hyperplasia is contemplated as a precursor lesion to invasive pulmonary adenocarcinoma.
The Collocating Receptacle-Collecting Duct Carcinoma
Authors: Bajaj Anubha
Published: January 2024

Collecting duct carcinoma configures as an exceptionally discerned renal cell carcinoma contributing to < 1% of renal neoplasms and depicts an aggressive clinical course. Tumefaction is confined to renal medulla and is posited to arise from principal cells of distal collecting ducts of Bellini. Collecting duct carcinoma is additionally designated as Bellini duct carcinoma or carcinoma of collecting ducts of Bellini. Therapeutic response to immunotherapy and chemotherapy is minimalistic. Prognostic outcomes are extremely adverse.
Scientific Evidence for the Cosmetic Skin and Hair Benefits of Hemp-derived Cannabinoids: A Review
Authors: GL* Smith
Published: January 2024

Cannabinoids derived from hemp, known as phytocannabinoids, are a group of approximately 120 bioactive compounds found in the Cannabis sativa plant. They have gained increasing attention in recent years, emerging as promising ingredients in the cosmetics industry due to their proven therapeutic and cosmetic benefits for skin and hair. It is worth noting that they do not produce psychoactive effects associated with tetrahydrocannabinol (THC). This paper summarizes the available published in vitro, in vivo and human studies on cosmetic benefits of cannabinoids for hair and skin. Several of the mechanisms of action of cannabinoids are novel and entirely different from all other cosmetic ingredients because they interact with specific receptors in the hair and skin cells to turn “on” or “off” cellular processes. In addition, there are issues related to the formulation, legal requirements and regulatory considerations associated with incorporating cannabinoids into cosmetics formulations as discussed.
Relevance of Informal Arts Education on Formal Visual Arts Education in Southeast Nigeria
Authors: CI Ibenegbu
Published: January 2024

The existence of informal arts education Centers has raised a lot of controversy in arts education and practice in Nigeria. Often people do not regard the products of these informal arts Centers as artists. They regard them as artisans even though most of them are being trained by formal artists and are being imbibed by their artistic traditions. It is, therefore, pertinent to investigate these informal arts Centers and assess their existence and their influence on formal arts Centers. This study was, therefore, designed to explore the assessment of informal arts education and its influence on formal art education in southeast Nigeria. The research questions were on the: educational relevance of informal arts education on formal art education, the influence of arts education on formal art education and on whether informal and formal art education can co-exist. I used a questionnaire to elicit information from the respondents. The findings revealed that the existence of informal arts education is relevant to formal art education, informal arts education influences formal art education and informal arts education can co-exist with formal art education. The paper recommended that the Ministries of Education should encourage and ensure that the formal art schools and informal arts Centers co-exist.
Cytoarchitecture of Cerebellar Cortex: Fractal Analysis as a Method for Quantitative Studies
Authors: N Maryenko
Published: January 2024

In this study we aimed to assess the possibility of fractal analysis utilization for the quantitative studies of cytoarchitecture in neuromorphology, namely in the studies of cerebellar cortex. We have chosen box counting method for fractal analysis. As an object of study we have chosen granule cell layer of cerebellar cortex. To estimate the informativeness of fractal analysis in the studies of cytoarchitecture and to assess the impact of the influencing factors (cell size, cell density or cell number, and pattern of cell distribution) we created artificial models of granule cells composition in the cerebellar cortex. We submit a proposition to consider the cell clusters and their assemblages as a whole entity. The cytoarchitecture as a whole entity exhibits some fractal properties: self-similarity of different scales, irregularity of the spatial configuration. Fractal dimension is the measure of space filling degree, so the fractal dimension measured in cellular groups characterizes space filling degree of cell assemblages. We revealed that the space filling degree depends on cell size, cell density (cell number) and pattern of cell distribution and clusterization. Increase in cell size or/and cell density (cell number) results in the increase in Fractal dimension values. Fractal dimension values are higher when cells are distributed evenly than when cells form the clusters. While the size and density (relative number) of cells can be estimated using traditional morphometric methods, the pattern of cell arrangement is mainly qualitative, and the fractal analysis allows to quantitatively and comprehensively assessing the cytoarchitecture of brain cortex.
A Note on Status and Breeding Biology of Birds-of-Paradise (Aves: Paradisaeidae)
Authors: A* Kabir
Published: January 2024

Based on the extraordinary plumage colours and courtship display, the birds-of-paradise are most significant bird in the world. To know its breeding biology fully, these birds can be study bird to everybody. After reviewing many write-ups, it was possible to mention its status and remarkable breeding biology. Noted, 27 species of these birds were in the order Passeriformes and family Paradisaeidae. Most of the birds were showed polygamous, and only two were (crinkle-collared manucode, Manucodia chalybatus, halmahera paradise-crow/Silky-crow, Lycocorax pyrrhopterus) monogamous. Observation suggested 15 genera of this bird group. Based on the information, 22 species were found least concerned (81.48%), near threatened 4 (14.81%), and vulnerable 1 (3.70%). Habitat loss, limited range, and for bright plumage of male birds, some species are showing their risky life in nature.
Daily Water Surplus Variability between the Mediterranean, Semi-Arid and Arid Climates
Authors: Y Aviad
Published: January 2024

Water surplus in a water balance is the fraction of precipitation which does not evaporate and not stored in the soil and includes both surface runoff and deep percolation. The annual course of the distribution of days with water surplus was estimated by a simple water balance model, which combines daily rainfall data, pan evaporation and soil water properties. The model was run using available published daily rainfall series and pan evaporation from ten Israel Meteorological Service stations, representing various climatic regions of Israel and using 21 different soil depths to simulate different root zone depths. The calculated daily water surplus series enable to evaluate the probability and amount of water surplus on each day of the year. The model output can be used in various hydrological models and be applied to other regions with similar conditions, without any special adjustment and may serve as an important tool for planners. This information is crucial for evaluation of the timing of occurrence of geomorphological and hydrological processes which depend on water surplus in various seasons. The annual aggregation of the water balance components provides a general view of the hydrological conditions of the different stations. The probabilistic representation of the results enables a comparison among stations with different rainfall regimes and soil types.
Polycystic Ovarian Syndrome - Its Ayurvedic Correlations and Management
Authors: S Singh
Published: January 2024

Polycystic ovarian syndrome is a systemic metabolic and endocrine disorder. The main causes of oligo/amenorrhea, hirsutism, obesity, and enlarged ovaries with numerous tiny cysts and thick tunica, which results in anovulation, are hyperinsulinemia and hyperandrogenemia. A few disorders in the Yoni Vyapad, Artava Dushti and Jatiharini group in Ayurveda resemble this entity in some ways, but Pushpaghni Jatiharini as described by Acharya Kashyap has a striking resemblance. According to Ayurveda, PCOS can be managed with Samshodhana Chikitsa and lifestyle modification. It can be prevented by adhering to Dincharya and Ritucharya, using Pathya Aahara, Vihara, and Aushadha, as well as by avoiding Apathya Aahara, Vihara, Prajnaparadha, Mandagni, and overindulging in sweets. And other etiological elements like Kaphavardhaka Aahar, absence of love and others. Therefore, lowering Kapha, adjusting insulin, eliminating obstructions, and using Aushadha, Aahara and Vihara can aid in the prevention and treatment of PCOS.
Indian Medicine Can Improve Quality of Life in Breast Cancer Patients: Case Studies
Authors: TK Sur
Published: January 2024

The present study was evaluated the QoL of breast cancer patients who were taking Body Revival, an Indian polyherbal medicine. A case study was conducted among 5 breast cancer patients, who were voluntarily treated with Body Revival for ≥6 months. The average age of 5 breast cancer patients was 48.6 yrs (range 35-64 yrs), out of them 3 suffered in Stage II and 2 in Stage IV with metastasis. 3 patients undergo surgery, 4 under chemotherapy treatment and 1 did not received any chemotherapy or surgery. All of them used Body Revival (average 13.2 months). A structured and validated interview schedule was used to gather data from cancer patients. The QOL of all the patient symptoms was significantly improved (p<0.001) with Body Revival supplementation. It improved both the psychological and physical domains of day-to-day life, either by attenuating the adverse events of regular treatments for cancer or by enhancing vital energy in the body. Conclusions: With Body Revival supplements with routine medical care improve their day to day life. To strengthen the present findings, more research is required.
Diet for Different Age Group Children in Ayurveda
Authors: HK Singhal
Published: January 2024

Diet i.e., Ahara is the one of the base of living being. Complexion, happiness, voice, life, talent, satisfaction, power, intelligence all etc. depended upon Ahara. In Ayurveda Ahara is base of life. Ahara is the best of all medicines and is considered one among the three sub-pillars of human life as per Ayurveda (Trayo-Upasthamba). Ayurveda emphasizes on nutrition of children for maintenance of health. It has classified children on the basis of diet into 3 categories viz. Ksheerapa (from birth to 1 year)- who take predominantly breast milk, Ksheerannada (from age 1-2 year)- who take both breast milk and food and the Annada (above 2 years of age)- who take food similar to an adult. Food is necessity of life because food provides energy as well as nutrition. Health depends solely on the food human intake. Health, Strength & life depends on Agni. But Agni is also constantly replenished from the nutrition. So, to maintain Samagni eating balanced foods are essential. Toddlers & Pre-schoolers need adequate intake to achieve full growth and developmental potential. Various life style disorders and numerous diseases occur due to faulty dietary habits which may be prevented by proper Ahara and eating habits.
Water as Discussed by Charaka, the Father of Indian Medicine
Authors: DK Goswami
Published: January 2024

Water, the unavoidable substance for each and every object of the nature, has been counted as sacred and respectable since time immemorial. Water is needed for making the soil fertile, growth of the plants, drinking for the animals and humans, external cleaning purposes of the human, animal etc., cleaning of the dress , utensil etc. of the human beings etc. If observed, it is seen that, water is used in huge quantity by the human itself. In each step a man needs water. Summarily to say, for a man it is almost impossible to live without water even for a hour. Hence it is occupying an important place in the literatures also. Many descriptions are available in the Indian literatures showing the importance of water. Water, along with its usefulness also may cause some sufferings to the human beings, animals etc. A good number of diseases are identified by the researchers that are transported by water when it becomes contaminated. Difference in the qualities of water according to different source is also an important point to be noted. Extensive study and research are already conducted and continuing in different levels to know more about the mysterious nature’s gift “water”. The present scientific society is aware about the latest knowledge on water. But astonishingly there are some interesting facts and concepts about water in the classics of ancient Indian health science, Charaka Samhita, Susruta Samhita, Ashtanga Sangraha, Ashtanga Hridaya etc. which should be apprised to the modern scientists and researchers. Hence, considering as the need of time, a study on the descriptions on water in one among the Ayurvedic classics, Charaka Samhita, which is considered to be the oldest is conducted.
Efficacy of Virechana Karma in Psoriasis (Ek Kushta) – A Case Study
Authors: S Singh
Published: January 2024

Psoriasis is a common autoimmune disease of the skin and joints that is chronic and recurrent. On the physical, emotional, and psychological wellbeing of the affected patients, it may have a profoundly detrimental effect. By alleviating symptoms, modern medicine has significantly improved the treatment of psoriasis. Finding the best course of action for some patients can be challenging since they do not respond to treatment or the treatment loses its initial efficacy. Modern medications also come with long-term negative effects of their own. Ayurveda classify the condition as Ek kushta, a Vata-Kapha predominant Kushta. Here, a traditional Ayurvedic regimen was attempted to treat a 41-year-old male with long-standing moderate to severe erythrodermic psoriasis who had previously received systemic therapy in modern medicine without receiving an adequate response. Samshodhana coupled with Samshamana medications are the cornerstones of treatment for all varieties of Kushta, hence in this study, Virechana was administered first, followed by 30 days of Samshamana medicine. At the conclusion of treatment, a skin lesion assessment was performed.