bluuebunny/crossref_metadata_2025 huggingface dataset:
Antitumor properties of nuclear erythroid cells
Authors: Kozlov V. A. , Seledtsova G. V. , Dorzhieva A. B. , Ivanova I. P. , Seledtsov V. I.
Published: June 2022

Purpose. To study suppressor and/or cytotoxic activity of the nuclear erythroid cells (NEC) against tumor cells of various origins. Material and Methods. C57Bl/6 mice and P815, L1210, B16 and L929 tumor cells were used. “Phenylhydrazine” NECs were obtained from mice with induced hemolytic anemia. “Erythropoietin” NECs were isolated from the “phenylhydrazine spleen” and further cultured in the presence of erythropoietin. Another source of NEC was neonatal mouse spleen, human and mouse fetal liver cells, and mouse bone marrow cells cultured with erythropoietin. The cytostatic effect of NEC or their supernatants was recorded by reducing proliferation of P815, L1210, B16, LLC, L929 lines. Results. The presence of pronounced direct antitumor activity was found in both NEC and their culturing products in relation to cells of various tumor lines. The suppressor effect was not specifc. Conclusion. We know about the signifcant numerical predominance of NEC during the embryo development over all other hematopoietic cells and their high suppressive potential. Therefore, it can be assumed that erythroblasts are involved in process of creating antitumor protection of a fetus during this period of life.
Antitumor, toxicity and target gene expression evaluation of MiR-204-5p mimic application on melanoma b16-bearing mice
Authors: Lapkina E. Z. , Palkinа N. V. , Averchuk A. S. , Esimbekova A. R. , Ruksha T. G.
Published: June 2022

Objective. To evaluate anti-tumor, toxic effect of miR-204-5p mimic applicaton on melanoma B-16-bearing mice followed by miR-204-5p target gene expression estimation in melanoma tumor and distant organs. Material and Methods. C57Bl/6 melanoma B-16-bearing mice were used. The animals of the experimental group were intraperitoneally injected with a 5 nM miR-204-5p miRNA simulator (mimic) on the 8th, 10th, and 12th days after melanoma B-16 cell transplantation. Based on the results of bioinformatic analysis, miR-204-5p target genes BCL2 and SIRT1 expression levels were determined by quantitative real-time PCR. The toxic effect of miR-204-5p mimic was estimated by the evaluation of body weight, mass of the internal organs, and motor activity. Results. On the 13-14th days of the experiment, the motor activity of animals in the control groups decreased signifcantly compared to the group of animals treated by miR-204-5p. Target gene BCL2 showed increased expression in the lungs and kidneys and SIRT1 levels were increased in the lungs of miR-204-5p mimic treated animals (p˂0.05). Tumor mass tended to decrease in the animals treated by miR-204-5p mimic. Conclusion. Modulation of the level of miR-204-5p microRNA led to changes in the expression of SIRT1 and BCL2 in the lungs of animals, and changes in the expression of BCL2in the kidneys. MiR-204-5p mimic application did not have toxic effect on animals treated. Further studies are necessary to clarify miR-204-5p implication in melanoma cell proliferation regulation as well as it’s biodistibution in the tumor tissue.
Reconstruction of postoperative defects using carbon nanostructured implants with intramedullary osteosynthesis after extremity long bone resection for primary and metastatic tumors
Authors: Safin I. R. , Rodionova A. Yu. , Rukavishnikov D. V. , Khasanov R. Sh.
Published: June 2022

Background. Recent studies have shown that a combination of surgery with chemotherapy and radiotherapy can signifcantly improve survival in patients with primary and metastatic bone tumors. Reconstruction of bone defects after resection of long bones is critical for successful functional limb salvage. The choice of the reconstruction technique depends on the tumor location, tumor extension, presence of pathological fracture, and somatic status of the patient. Reconstruction of bone defects in cases with diaphyseal tumor location can pose a surgical challenge. For the reconstruction of diaphyseal bone defects, endoprostheses, alloimplants, and autologous bone grafts are used. To achieve stability of the affected segment of the limb, various options for osteosynthesis are used. Modern technological achievements provide the emergence of materials with characteristics close to those of human bone tissue, however, without the disadvantages inherent in allo- and autologous implants. The purpose of the study was to improve surgical treatment outcomes in patients with long tubular bone tumors. Material and Methods. For the reconstruction of postoperative long bone defects, we used carbon nanostructured implants (СNI) in combination with intramedullary osteosynthesis with a blocked pin. A total of 25 patients underwent surgery (including 9 patients with a pathological fracture), 24 of them had metastases. Results. There were no intraoperative and postoperative complications. All patients had a signifcant decrease in pain 1 month after surgery. At 3 months after surgery, functional outcomes were satisfactory. None of the patients had a local recurrence, instability of the operated limb segment, or a reaction of rejection of a carbon nanostructured implant. Conclusion. Reconstruction of postoperative defects with carbon nanostructured implants after resection of long tubular bones for metastatic cancer provides good functional results and satisfactory local control.
Value Co-Creation Approach to Management of Construction Project Stakeholders
Authors:   Faculty of Arts and Science, International University of Malaya-Wales (IUMW), Kuala Lumpur, MALAYSIA, Asiedu Richard , Iddris Faisal ,   Department of Management Studies, Akenten Appiah Menka University of Skills Training and Entrepreneurial Development, Kumasi, GHANA
Published: June 2022

This article explores the link between value co-creation, a project's success and satisfaction of the project's stakeholders. It also looks at how a project's success mediates the relationship between value co-creation and the stakeholder's satisfaction. A quantitative approach with an online questionnaire was used to collect data from a sample of 140 respondents in Ghana. Data were analysed using partial least square structural equation modelling (PLS-SEM). The results show that value co-creation positively and significantly relates to a project's success and stakeholder satisfaction. The findings also support that a project's success mediates the impact of value co-creation on the stakeholders' satisfaction. Based on these findings, we suggest that project managers be critical about the type of value co-creation strategy they will use to engage project stakeholders. This would apply when adopting the value co-creation approach to manage their projects while not sacrificing success. This study focused on the impact of value co-creation on a project's success and its stakeholder's satisfaction. The survey data were collected only to evaluate the overall effect of value-co-creation on the success and stakeholder's satisfaction of projects. The adoption and implementation of value co-creation in project management may enhance the definition of the project's scope, performance specifications and other criteria used to measure the success of a project, to meet the needs of stakeholders. By empirically presenting a project's success as a key mediator in shaping the effect of adopting value co-creation in project management on the stakeholder's satisfaction, this study laid a foundation for further theoretical explorations involving value co-creation in project management.
Application of Linear Scheduling in Water Canal Construction with a Comparison of Critical Path Method
Authors:   School of Civil Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, INDIA, Ramani Prasanna Venkatesan , Selvaraj Ponnambalam ,   School of Civil Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, INDIA, T. Shanmugapriya ,   School of Civil Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, INDIA, Gupta Anshul ,   School of Civil Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, INDIA
Published: June 2022

Critical path method (CPM) still remains the most commonly used scheduling technique, despite many studies confirming its shortcomings for scheduling repetitive construction projects. This research evaluated the case study of an alignment-based precast water canal erection project, which was originally planned with CPM and analysed the suitability of using linear scheduling method (LSM) for the same project. The case study project was scheduled using both CPM and LSM tools and the results were compared in terms of estimated total duration and resource cost. The results showed that LSM produced a saving of 10 days in total duration and 20.07% in estimated resource cost over CPM. LSM also proved to be the better tool in terms of other schedule attributes like resource assignment, levelling, visualisation, etc., for alignment-based projects. LSM can be highly efficient for scheduling different types of repetitive construction and offers benefits like better workflow and continuous resource usage.
Evaluation of Service Quality Gaps in Construction Professional Service Firms in Nigeria
Authors:   Department of Architecture, Olabisi Onabanjo University, Ibogun Campus, Ogun State, NIGERIA, Raphael Aluko Olusola , Samuel Omoniyi Sunday ,   Department of Architecture, Olabisi Onabanjo University, Ibogun Campus, Ogun State, NIGERIA, Dipeolu Adedotun Ayodele ,   Department of Architecture, Olabisi Onabanjo University, Ibogun Campus, Ogun State, NIGERIA
Published: June 2022

The study aims at evaluating and comparing service quality of consultancy firms who provide professional services in building projects in Nigeria. The article seeks to address the general perceptions of dissatisfaction with the quality of services in order to enhance performance of building projects and ensure competitiveness in the industry. A cross-sectional survey was conducted using a structured questionnaire as an instrument of data collection. The population of the study consisted of 488 representatives of public and private clients with a sample size of 385. Data were analysed using weighted mean and paired-sample t-test to determine the severity of differences in the expected service quality and perceived service quality. The result shows significant differences between the expected service quality and perceived service quality in structural engineering, mechanical/electrical engineering and quantity surveying services along all the dimensions of service quality. However, "Tangibles" dimension of architectural services had no positive differences in the service quality, but had differences in "Responsiveness", "Empathy", "Reliability" and "Assurance" dimensions. The results imply that professional service providers require fundamental improvement in their services to their clients. This study offers an opportunity for consultancy firms to evolve global best practices by creating and maintaining high service quality as a team.
Single-crystal X-ray diffraction of fluorapatite to 61 GPa
Authors: Rucks Melinda J. , Finkelstein Gregory J. , Zhang Dongzhou , Dera Przemyslaw K. , Duffy Thomas S.
Published: June 2022

Apatite is a mineral of widespread importance in Earth and planetary science. Here we examine the behavior of a natural fluorapatite (FAp) crystal from Durango (Mexico) under compression to 61 GPa. Single-crystal X-ray diffraction experiments were carried out in a diamond-anvil cell using a synchrotron source. The apatite structure persists up to 32.4 GPa. Birch-Murnaghan equation of state parameters were fit to the pressure-volume data for fluorapatite for two cases: fixing V0 at its measured ambient value resulted in a bulk modulus, K0T, of 97.0(8) GPa and a pressure derivative of the bulk modulus, K0T′, of 3.3(1), while fixing V0 and K0T at its ambient value 90.5 GPa (derived from ultrasonically measured elastic constants) resulted in a K0T′ value of 4.1(1). At 35.6 GPa, fluorapatite transforms to a triclinic phase (P1, Z = 4), designated here as fluorapatite II (FAp-II). This phase persists up to at least 61 GPa. The major structural differences between FAp and FAp-II involve the buckling of the Ca polyhedra along the c-axis and changes in the number and coordination of the Ca sites. Our study extends the pressure range over which fluorapatite has been examined by more than a factor of three, providing new insights into its structural response to high-pressure conditions.
Fragmentation of Media Audience: from global village to global theater
Authors: Kirillina N. V.
Published: June 2022

The development of mass media and social networks has radically changed the consumption of content by the audience, which has in fact turned into relatively separated communities of users, i.e. subjects of communication processes. Users get and actively use the possibility to choose the format, the channel and the content based on their personal experience, psycho-emotional state, socio-cultural characteristics. However, the users choice is not always conscious, and besides that, the users self-identification and further choice of channel and content is often based on ‘friend-or-foe’ principle, which leads to an increase in social and political polarization in the process of media consumption. The paper is based on the analysis of Russian and foreign sources dedicated to the behaviour of the audience of modern media and to the processes associated with fragmentation and demassification of the media audience. As follows from the analysis of these sources and from the standpoint of a structural approach to the study of social systems, the fragmentation of the audience and the polarization of public opinion are conditioned, besides arising political barriers, by the peculiarities of the functioning of the modern media system, i.e. make part of its attributive characteristics.
Plain and easy language as a new trend of communication between the state and society
Authors: Katysheva L. V.
Published: June 2022

Analyzing the modern communication practices of authorities at different levels, as well as speeches and posts on social networks of a number of Russian officials, the author of points to noticeable changes in the style of communication between the state and society compared to previous periods. These changes seem to be caused by the need for the authorities to master the increasingly popular new media and communicate with an audience that, due to its training, cannot perceive information in an official style. The trigger of these changes, outlined since the advent of new means of communication and supported by the active spread of the Internet, was the situation of the coronavirus pandemic, which required the state to build crisis communications that require clarity of messages, speed of their delivery and appeal to the emotions of the audience. The noted changes can be considered a trend that will only intensify, including due to the growth in popularity of ‘plain and easy language’ observed in many European countries, which has become a response to the problem of low level of reader literacy. However, it will mainly be supported due to the active development of new formats of communication between the state and society, built on the basis of popular social networks among the audience, which can be considered the result of the so-called fifth communication revolution, which blurs the line between written and oral speech and leads to the emergence of new speech genres. State institutions willingly accept changes and express a desire to seek a new tone of voice in communication with citizens, as well as to learn relevant communication practices.
APPORT DE LA GEOMATIQUE ET DES STATISTIQUES SPATIALES POUR LA CARTOGRAPHIE ET LANALYSE DES DEPRESSIONS EN LIEN AVEC LES POTENTIELS GITES LARVAIRES DANS LE DISTRICT SANITAIRE DE COCODY-BINGERVILLE
Authors:   Centre Universitaire de Recherche et dApplicationenTeledetection (CURAT), Universite Felix HouphouetBoignydAbidjan., Kouame Ndri Felix , Krou Damien Kouame Adonis ,   Centre Universitaire de Recherche et dApplicationenTeledetection (CURAT), Universite Felix HouphouetBoignydAbidjan., Aya Nguessan Nicaise ,   Laboratoire de Zoologie et BiologieAnimale, Universite Felix HouphouetBoigny, Abidjan, Cote dIvoire., Valere Djagoua Eric ,   Centre Universitaire de Recherche et dApplicationenTeledetection (CURAT), Universite Felix HouphouetBoignydAbidjan., Celestin Hauhouot Asseypo ,   Institut de GeographieTropicale (IGT), Universite Felix HouphouetBoigny, Abidjan, Cote dIvoire.
Published: June 2022

Contribution of geomatics and spatial statistics for the mapping and analysis of depressions related to potential larvate locations in the health district of cocody-bingerville.The depressions or basins in the landscape constitute zones of water stagnation and present themselves as potential favorite zones for the female Anopheles mosquito to lay her eggs. This increases the vectorial capacity with the consequence of a risk of malaria attack for the population in the health district of Cocody-Bingerville. The objective of this study is to analyze the geostatistical distribution of depressions in order to contribute to vector control.Sheis based on geospatial and statistical analysis of depressions in said health district. Thus the integration and processing of AlosPalsar data of 12.5 m spatial resolution in a GIS and spatial autocorrelation techniques have been applied for the modeling of depression zones. The presence of local clusters was further assessed using Morans statistical index to assess the intensity of hot spots (High-High Cluster) and cold spots (Low-Low cluster).Local statistics from Moran I were used to perform cluster and value analysis in the spatial distribution of depressions in the landscape. It reveals a z-score of 56.91 and a Morans index of 0.07. These positive statistical values attest that the observed phenomenon is highly dependent on the topography, hence the groupings or clustering of the depressions.
CORRELATION OF BURNOUT DIMENSIONS AND SUBSTANCE USE AMONG TAIBAH UNIVERSITY MEDICAL STUDENTS IN AL-MADINAH AL-MUNAWARAH, SAUDI ARABIA
Authors:   Family Medicine Academy of Medina, Saudi Arabia., Mubarak Al Johani Afaf , Abdulqader Alrehaili Eyas ,   Faculty of Medicine, Taibah University, Saudi Arabia., Essam Khalil Faisal ,   Program of Family Medicine Postgraduate Studies, Saudi Arabia., Mubarak Aljohani Ohood ,   Pharmacy Department, King Faisal Specialist Hospital & Research Center, Saudi Arabia.
Published: June 2022

Objectives:To assess the level of burnout dimensions and investigate their correlation with substance abuse among undergraduate medical students at Taibah University in Al-Madinah Al-Munawarah, Saudi Arabia. Methods: This was an analytical study conducted at Taibah University, Al-Madinah, from January 2021 to July 2021. A self-administered questionnaire consisted of two sections. The first section identified the socio-demographic and personal characteristics of the participants. The second section presented the Maslach Burnout Inventory-Student Survey (MBI-SS). SPSS v26 was used for data analysis. Results:Of the 534 participants, 53.9% were females. The students mean (SD) age was 21.4 (1.59) years. Findings showed that 6% of the medical students had once used one or more types of substances, of which the majority (53.3%) used sleeping pills or sedatives. The average emotional exhaustion mean score of students in the survey population was 3.65 (1.46) out of 5. The students perceived emotional exhaustion scores were correlated significantly and positively with the total number of abused substances, p<0.050. The medical students total number of substance-used materials correlated significantly but negatively with their sense of personal study effectiveness, p<0.050. Students who had a positive history of substance use showed significantly higher cynicism (M=3.88) compared to students who had never abused substances (M=3.00) on average, p<0.001. Conclusion:Medical students at Taibah University demonstrated higher mean scores for emotional exhaustion and cynicism but a lower mean score for personal effectiveness. The students top burnout indicator was emotional exhaustion, followed by personal efficacy and cynicism.
PREVALANCE OF DIABETES IN CATARACT PATIENTS AT TERTIARY CARE CENTRE
Authors:   Associate Professor, Sri Devaraj Urs Medical College Kolar., B.R Usha , Patade Yugandhara ,   Junior Resident, Sri Devaraj Urs Medical College Kolar., Patel Aparna ,   Junior Resident, Sri Devaraj Urs Medical College Kolar., T.R Manjula ,   Professor and HOD, Sri Devaraj Urs Medical College Kolar.
Published: June 2022

Objective:To know the prevalence of diabetes in cataract patients. Methodology:A prospective observational study conducted in ophthalmology department. The total number of patients including males and females having cataract were included. The duration of the study was 6 months including all age groups. Torch light and slit lamp examinations were done. For all those patients who were not previously diagnosed as having diabetes, fasting blood glucose estimation was evaluated twice: once in the field using capillary blood and a second time at the base hospital using venous blood (glucose oxidase method). Patients were considered to be newly diagnosed subjects with diabetes if fasting bloodglucose level was 110 mg/dl or more on 2 occasions, as described previously. The lens opacity is classified based on lens opacity classification system (LOCS III) comparing with the standard photographs system. Conclusion:In our study 44.5% patients had diabetes with cataract.
THE COMPARATIVE STUDY OF USG AND MDCT IN THE EVALUATION OF PELVIC MASSES IN FEMALES
Authors:   Junior Resident, Department of Radiodiagnosis, Ravindra Nath Tagore Medical College, Udaipur., Rajoria Anupam , Kumar Kardam Narendra ,   Senior Professor, Department of Radiodiagnosis, Ravindra Nath Tagore Medical College, Udaipur., Gehlot Kushal ,   Professor, Department of Radiodiagnosis, Ravindra Nath Tagore Medical College, Udaipur., Kumar Ola Sandeep ,   Assistant Professor, Department of Radiodiagnosis, Ravindra Nath Tagore Medical College, Udaipur.
Published: June 2022

Introduction: Pelvic masses in females of all ages are a routine gynaecological issue for which healthcare is sought, and in a populous country like India, these masses form a significant part of the disease burden. The evaluation of the female pelvis is a radiological necessity and a challenge. The foremost aim for any imaging modality in this scenario is to rule out malignancy in the mass, and further to characterise and define the mass so as to guide appropriate management of the patient. Of the wide range of imaging modalities available, ultrasonography and computed tomography are commonly available and extensively used for the evaluation of the varied female pelvic masses. We studied the ultrasonography and multi detector computed tomography findings and their usefulness in the diagnosis and characterization of various pelvic masses in females. Methodology: It was a prospective observational study, ranging over the duration of one and a half years,of 100 female patients fulfilling inclusion criteria, who underwent ultrasonography and multidetector computed tomography scanning in the Department of Radiodiagnosis at RNT medical college, Udaipur. Pelvic masses were evaluated for origin, size, margins, composition, vascularity, ascites, lymphadenopathy and other features to characterise as benign or malignant. Final diagnosis was by histopathological correlation. Results: The most common age group belonged to 35-45 years group (22%) followed by 55-65 years group (21%). Mean age for benign masses was 35.84 years and for malignant masses was 51.64 years. Ovarian origin was the commonest followed by uterine origin. Features like solid areas, ill-defined margins, lymphadenopathy and ascites favoured malignancy. Most common pathologies were adenocarcinoma ovary, carcinoma cervix, benign ovarian cysts and uterine fibroids. Conclusion: Ultrasonography is often the first imaging study performed in patients with symptoms related to the pelvis. Results indicated higher diagnostic capability of CT as a problem-solving tool. Overall diagnostic accuracy of CT was higher than USG in characterising both benign and malignant pelvic masses.
TWINS - AN ALTERNATIVE OPTIMAL TOUR PLANS GENERATION METHOD TO TRAVELING SALESMAN PROBLEMS
Authors:   Associate Professor, Department of Mathematics, St. Johns College, Palayamkottai-627002, Affiliated to Manonmaniam Sundaranar University, Tirunelveli-627012, Tamil Nadu, India., Murugesan R.
Published: June 2022

A traveling salesman problem (TSP) is an assignment problem (AP) with extra conditions, in which the aim is to find the best possible way of visiting all the planned cities only once and returning back to the opening point that minimize the travel distance (or time or cost) on the whole. In the modern world, TSP occupies a major role. The eminent method used to solve the TSPs is the Hungarian method. In this research article, we have identified and established a list of TSPs which are having alternative optimal tour plans (OTPs). For the identified TSPs, the alternative OTPs are generated by applying the proposed TWINS method. The main aim of developing alternative OTPs by the management is to have the best possible decision out of the available alternative solutions. Solution alternatives also can make it easier to make use of these options in the future during disaster situations. The alternatives identified become a base for subsequent analysis by the management and eventually the decision itself.
THE ROLE OF TRANSCRANIAL ULTRASOUND IN THE EVALUATION OF HYPOXIC ISCHEMIC ENCEPHALOPATHY
Authors:   Junior Resident, Department of Radiodiagnosis, RNT Medical College, Udaipur., Sharma Manoj , Kumar Kardam Narendra ,   Senior Professor, Department of Radiodiagnosis, RNT Medical College, Udaipur., Babu Gehlot Kushal ,   Professor, Department of Radiodiagnosis, RNT Medical College, Udaipur., Gupta Shruti ,   Junior Resident, Department of Radiodiagnosis, RNT Medical College, Udaipur.
Published: June 2022

Introduction: Hypoxic ischemic encephalopathy is a clinical term used to describe an abnormal neurobehavioral state that consists of a decreased level of consciousness with abnormalities in neuromotor tone. Any neonate, regardless of birth weight, size, or gestational age, who has a greater than average chance of morbidity or mortality, due to fetal, maternal or placental anomalies or an otherwise compromised pregnancy especially within the first 28 days of life is categorized as high-risk neonate. Cranial ultrasonography plays an important role in the diagnosis of significant lesions in infants presenting with hypoxic ischemic encephalopathy (HIE) and seizures and assessing severity, neurodevelopment outcome and neurological prognosis of these high-risk infants. In the neonate, many sutures and fontanelles are still open and these can be used as acoustic windows to look into the brain. Methodology: This was a hospital based descriptive observational study of 100 preterm and term babies with suspected brain injuries who were referred for cranial USG examination to the Radiodiagnosis Department of R.N.T. Medical College, Udaipur with hypoxic ischemic encephalopathy over a period of 18 months from June 2020 to November 2021. Results:The most common affected age group was 32-37weeks (51%). The abnormalities found on neurosonogram were germinal matrix hemorrhage, periventricular leucomalacia, cystic PVL, cerebral edema and ventriculomegaly. The most common abnormality was germinal matrix hemorrhage (17%) and subependymal hemorrhage (41%) was most common type. Isolated ventriculomegaly (53.8%) was more common than ventriculomegaly with hemorrhage (46.2%). Conclusion: Neurosonogram remains the accurate, rapid imaging modality of choice for detecting brain injuries in preterm infant. This technique is both sensitive and specific for detecting germinal matrix hemorrhage and periventricular leucomalacia. It is a useful modality to perform frequent follow-up scans. The advantages of neurosonogram are that it is easy to operate, non invasive, accurate, has lack of ionizing radiation, bed side availability for unstable infants, rapid diagnosis, wide availability, cost effectiveness and repeatability.
ANATOMIE DE LOREILLE INTERNE : LES CANAUX SEMI-CIRCULAIRE DAPRES UNE MODELISATION TRIDIMENTIONNELLE
Authors: Nakkabi Ismail , Ridal Mohammed , Benmansour Najib , Nadour Karim , El Boukhari Ali , Noureddine El Amine El Alami Mohammed
Published: June 2022

Le present travail sinteresse a lanatomie de loreille interne et particulierement celle des canaux semi-circulaires. Il sagit dune etude combinant des moyens dimagerie de haute resolution (TDM de rochers) a des outils informatiques simples et disponibles gratuitement sur internet. Cecia rendu possible la visualisation et letude precise de certains parametres anatomiques. Nous avons obtenu des resultats graphiques et numeriques. les resultats graphiques, permettant de voir le rendu en 3D de ces structures,peuvent avoir plusieurs applications pratiques, notamment a des fins pedagogiques. Les resultats numeriques demontrent quil y a une variabilite inter individuelle pouvant expliquer la reponse de chacun a des test diagnostiques et therapeutiques de vertige.
EVALUATION AND QUANTITATIVE ANALYSIS OF BIOACTIVE COMPOUNDS FROM CHAETOCEROUS CALCITRANS AGAINST HUMAN PATHOGENS
Authors:   Professor, Department of Biomedical, Sri Shakthi Institute of Engineering and Technology., Mercy Bai Dooslin , Kousik Saravana S. ,   Research Scholor, Department of Biomedical, Sri Shakthi Institute of Engineering anfd Technology.
Published: June 2022

The distribution of secondary metabolites and pharmacologically dynamic complexes from marine microalgae has increased in the previous decade. The antibacterial metabolites lessons in the current search were taught by Chaetoceroscalcitrans. Methods :Chaetoceroscalcitrans(green algae) was chosen as the subject of the existing secondary metabolites study. The properties of pH, temperature, and salinity were tested to see if they aided in the growth of microalgae. Dissimilar solvent extracts of Chaetoceroscalcitrans were tested for antibacterial activity against Vibrio cholerae ,Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Salmonella sp.,Proteus sp., Streptococcus pyrogens, Staphylococcus aureus, Bacillus megaterium, and Bacillus subtilis. Result : The uppermost cell growth was detected during the 9th day of incubation when the medium was adjusted with pH of 9.0 in 30 ppt of salinity at 25C. Butanol + Isopropanol(1:1) crude extract of Chaetoceroscalcitrans had the largest zone of inhibition (13.4 mm) against Salmonella of all the solvents tested. . For the crude extract of Chaetoceroscalcitrans, GC-MS analysis revealed the presence of unique chemical compounds such as 3, 3, 5-Trimethylheptane (M.W. 142.2) and n-Hexadecane (M.W.226.2), respectively. Conclusion:These results show that the Butanol + Isopropanol (1:1) extract of Chaetoceroscalcitranshas significant antimicrobial activity and thus has great potential as a solvent for extracting bioactive compounds from natural sources for biomedical and pharmaceutical applications.
THE EFFECT OF CONCENTRATION AND DURATION OF SOAKING ONION EXTRACT OF BATAK (ALLIUM CHINENSE G. DON) ON THE QUALITY OF LAMB MEAT
Authors:   Faculty of Science and Technology, University of Pembangunan Panca Budi, Medan, Indonesia., Asmaq Nur , Wibowo Fachrina ,   Faculty of Science and Technology, University of Pembangunan Panca Budi, Medan, Indonesia.
Published: June 2022

This study aims to determine the effect of the concentration of Batak onion extract (A. chinense G. Don) and storage time on the quality, quality and concentration of the best Batak onion extract in lamb. The samples used in this study were Batak onions (A. chinense G. Don) and lamb. This study used an experimental method with a factorial completely randomized design with a 4 x 4 x 2 pattern. Factor A was the concentration of Batak onion extract (BOE), namely A0: without treatment, A1: 10%, A2: 20% and A3: 30%, while factor B is the length of immersion, namely B0: 0 hours, B1: 1 hour, B2: 2 hours and B3: 3 hours. Parameters observed in this study were water content, pH value, cooking loss and total bacterial colonies of lamb. The results obtained in this study showed that the analysis of variance for each variable was very significantly different (P<0.01) so it was continued using the Duncan Multiple Ranges Test (DMRT) further test. Further test results showed a significant interaction (P<0.05) between Batak onion extract and soaking time on the observed parameters. The best values â€‹â€‹of water content, pH and total colony were in treatment A2B1 with a value of 76.92%, 6.9 and A2B1 6 x 103 CFU/g, while the best cooking loss value was in treatment A3B2 with a value of 48.4%.
A cross-impact analysis of the bank payment card market parameters and non-financial sectors’ indicators in the Ukrainian economy
Authors: Mints Aleksey , Kolodiziev Oleh , Krupka Mykhailo , Vyshyvana Bohdana , Yastrubetska Lesya
Published: June 2022

In Ukraine, card payment systems develop at a rate similar to that of modern digital payment instruments in most European countries. The purpose of the paper is to establish interdependence and explain the nature of changing situations in the market of bank payment cards (BPC) taking into account the dynamics of economic development parameters in non-financial sectors of the Ukrainian economy. The methodology of the study includes graphic methods analyzing the dynamics of economic development indicators and a method for analyzing the cause-and-effect relationship between the studied parameters considered with different lags. Results showed that the most significant parameters for the development of the payment card infrastructure were the level of provision with POS terminals and the share of non-cash transactions. Their correlation with the economic development indicators reached 0.97. Up to the stage when the volume of non-cash payments by cards reached 5% of GDP, the impact of the BPC market on the change in the level of economic development had been insignificant according to the general idea. The development of the economy up to that point stimulated the development of the BPC market. Subsequently, the BPC market that was already sufficiently developed became one of the drivers aimed at the development of non-financial sectors of the Ukrainian economy after overcoming the 5% GDP level.
Assessment of the relationship between inequality, income and economic growth in the regions of Kazakhstan
Authors: Turkebayeva Karina , Bekturganova Makpal , Sabden Orazaly , Dauliyeva Galiya , Kenzhegulova Gaukhar
Published: June 2022

This paper aims to analyze various indicators to explain the impact of inequality and income on economic growth at the regional level of Kazakhstan. The data collected from the Bureau of National Statistics from 1995 to 2020 examined the impact of country, interregional, and market inequality indices and real income/wage on the GRP of different regions. Applying the methods such as analysis of unique statistical data covering 16 regions of Kazakhstan and log-linear multivariate regression analysis, which was carried out using the STATA software package, evidence was provided on the influence of interregional, country inequality, and income on economic growth. The analysis showed the differential impact of inequality and income. It was found at the first stage that the gap between interregional inequality and country inequality is insignificant. It was identified at the second stage that in models with real incomes, an increase in income has a negative impact on the development of the economy of Kazakhstan. All the models obtained are consistent and have (although not very high) significant explanatory power and confirm the relationship between inequality and economic growth. The findings can help policymakers, regionalists, economists, and governmental bodies understand the importance of income inequality and which areas can contribute to the formation of effective regional policy.
AcknowledgmentsThe study was carried out within the framework of program targeted IRN OR11465433 funding by the Science Committee of the Ministry of Education and Science of the Republic of Kazakhstan “Development of the concept and mechanisms of balanced territorial development of the economy and society of Kazakhstan”.
Antalya Community Center Fine Arts Branch Activities
Authors: TOSİK DİNÇ Fadime
Published: June 2022

Mustafa Kemal Atatürk, who was based on the public since the years of the War of Independence, formed the new state he founded in behalf of public, for the interests of public and made the revolutions accordingly.However, after the closure of the Free Republican Party in 1930, the national tour and the Menemen incident led him to see that the revolutions were not adopted by the people and that the clash between the intellectuals and the people continued since the Ottoman Empire, so he had the community centers established on February 19,1932 to explain, make the revolutions adopt and eliminate the intellectal-public clash.The establishment of 9 branches within the community center was also agreed to grow citizens who combine national and universal values in the community centers. These branches were ranked according to the degree of importance given in the instruction and the Fine Arts Branch took its place as the second branch after, Language, Literature and History Branch.Atatürk had this branch established to develop art in these lands which didn’t develop for years, to create interest in art in the public and to protect those who are talented. The Antalya Community Center took its place in the second group among the opened community houses and was opened on June 24, 1932 with its 9 branches. In this article, the music and painting activities of the Antalya Community Center Fine Arts Branch were wanted to be revealed.In the preparation of the study, Republic Archive, Republican People's Party activity reports and brochures, Turkish Mediterranean Magazine issues published by Antalya Community Center, local newspapers and studies were used and the identified works were evaluated by using the document review model, one of the qualitative research methods.
The Teachings of Jihad in The Involvement of Samaniyah Tarekate in The War of Menteng 1819: A Historical Analysis
Authors: Prayogi Arditya , Subhi M. Rifa’i , Shilla Rhischa Assabet
Published: June 2022

Sufism is often accused of causing the decline of Islam because its teachings are full of fatalism, occultism, escapism, and irrationalism. Adherents of the trek are also often regarded as an exclusive, selfish, and asocial community. But in fact, the existence of Sufism can go hand in hand with the teachings of jihad, which is one of the teachings with values that are contrary to the assumption of the importance of Sufism. This article aims to reveal that the trek's practice in its history moved the spirit of struggle. This article was written using historical methods such as heuristics, criticism, interpretation, and historiography. It can be concluded in this article that the teachings of jihad can be well applied to tarekat adherents, especially to the Samaniyah order in the Menteng war incident. The involvement of the Samaniyah orders in the Menteng war proved that Sufism, apart from being identical to the spiritual dimension, could also move into the social size. The teachings of jihad introduced by Abd Shomad al-Palimbani, as well as his students' involvement, became the key to the participation of the Samaniyah order in the Menteng war of 1819, which led to the victory of the Palembang side over the Dutch in the Menteng war of 1819.
ARGUING FOR THE “DESTRUCTION” OF THE A PRIORI. THE PROMPTS FROM HUSSERLIAN PHENOMENOLOGY
Authors:   University of Patras, Department of Mathematics, LIVADAS STATHIS
Published: June 2022

This article argues against the concept of a priori and essence as they have been traditionally thematized in the course of the old metaphysical-idealist tradition. Specifically, I argue against the existence of an ontological a priori, often endowed with metaphysical-platonic connotations, by attempting to “relocate” it in the subjective sphere and thus reduce it to the being and modes of being of a transcendental subjectivity. To do so, I will be appealing to a phenomenological, Husserlian approach, while pointing to a possible connection with the Kantian views on the matter and also taking into account certain views in the secondary literature. Since a substantial part of my position is associated with the notion of a constituting, transcendental subjectivity further reducible to the origin of inner temporality, I intend to show that the objectivity constraints put in this way on the conception of the transcendental a priori may ultimately lead to a “destruction” of its traditional ontological sense. Given that in transcendental phenomenology the concept of a priori “appears” both in the constituting and the constituted level, I aim to show that it is precisely in this context that the a priori cannot rid itself of the vestiges of factuality brought in by means of the very constitutive, subjective processes implying ipso facto the question of the role of the constituting origin of temporality.
VASILI SESEMAN’S TRANSCENDENTAL THEORY OF KNOWLEDGE: BETWEEN PHENOMENOLOGY AND NEO-KANTIANISM
Authors:   Russian State University for the Humanities, SHIYAN ANNA
Published: June 2022

The article considers the theory of cognition of the Russian and Soviet philosopher Vasily Seseman (1884-1963) in its relation to the main philosophical orientations in early 20th-century: phenomenology, neokantianism, and intuitionism. Seseman’s theory of cognition is interesting today because, following the tradition of neo-Kantianism, it largely shares the principles and methods of phenomenology, poses epistemological problems that were not explicitly formulated by Edmund Husserl, and offers solutions that are relevant today. The article highlights a common thematic field combining phenomenology, neo-Kantianism, and intuitionism. This field is set by the initial subject-object cognitive attitude, the desire to identify the conditions for the possibility of cognition, the recognition of the presence of a non-linguistic level of knowledge. Moving in this unified theoretical cognitive context of the early twentieth century, Seseman offers his own solution to the following problems: defining the subject of cognition, developing the method of intuition in general and in relation to the contemplation of essence, distinguishing between objective and non-objective attitudes and using this distinction to describe different types of cognition, thematizing the irrational in cognition, and understanding the judgment and its role in the final formation of cognition. Seseman believes that the cognition of reality is preceded by the perception of its objects. He diverges from the Neo-Kantians, who claim that the objects of cognition are formed only in judgment, and holds a position than Husserl, according to whom we perceive the world around us already objectively. However, unlike Husserl, Seseman does not recognize the cognitive nature of perception and argues that knowledge begins with a reflexive fixation of the object of cognition. The cognition of an individual object is embodied in a judgment in which the relation of the object to its environment is fixed and the object is defined as a unique combination of universal properties. Finally, it is shown that the solution of epistemological questions inevitably leads Seseman to ontological issues.
WITTGENSTEIN’S DISAPPEARING IDEALISM
Authors:   National Research University Higher School of Economics, ROGONYAN GARRIS
Published: June 2022

The article examines some well-known attempts to consider Ludwig Wittgenstein’s Philosophical Investigations in the context of transcendental idealism. The main purpose of these attempts is to protect Wittgenstein’s later philosophy from the relativistic interpretation of such concepts a “language games” and “forms of life.” Thus, Bernard Williams, noting the ambiguity of the pronoun “we” in Philosophical Investigations, believes that such a “we” has a transcendental rather than empirical character. This approach allows Williams to argue that there is no meaningful alternative to the general perspective on the world that is embodied in this “we.” However, the main disadvantage of this approach is that Williams views such a “we” in much the same way as a conceptual schema. However, as many authors point out, this idea does not find its confirmation in the later works of Wittgenstein. Jonathan Lear, in turn, suggests that we should consider such a non-empirical “we” as a special kind of “mindedness.” Such a mindedness could be considered as analogous to a Kant’s analytical principle of apperception. Lear believes that it is this principle that gives meaningful unity to human behaviour and makes possible any communication with other people. Following Williams and trying to correct the shortcomings of his position, Lear proposes to consider the ambiguous status of “we” in Philosophical Investigations as an argument in favour of the “disappearance” of the transcendental “we,” and with it the disappearance of the threat of relativism. John McDowell, however, agreeing with the need to get rid Wittgenstein's philosophy of relativistic interpretations, critically assesses the idea of using transcendental idealism for this purpose. Instead, McDowell proposes to return to Hegel’s thesis about the unboundedness of the conceptual, which makes it unnecessary to appeal to the transcendental justification of harmony between reason and the world. The article, therefore, also examines McDowell’s arguments against attributing to Wittgenstein any versions of transcendental idealism.