bluuebunny/crossref_metadata_2025 huggingface dataset:
Trans-jugular intrahepatic portosystemic stent shunting benefits and limits
Authors: Sciarrone Salvatore Stefano , Fini Lucia , De Luca Luca
Published: December 2024

Trans-jugular intrahepatic portosystemic stent shunting (TIPSS) has been in use for many years with great results and many evolutions. The procedure essentially involves the insertion of a metal covert stent to create an Hepato-Hepatic portosystemic shunt. Over time, TIPSS has become the subject of many studies aimed at examining its clinical utility and evaluating the results of using TIPSS to manage complications related to portal hypertension. From the outset, this procedure has been met with hope and enthusiasm and give the chance to consider another possibility to treat the complications of portal hypertension without the use of surgery. Considering that TIPSS is an attractive alternative to shunt surgery because it does not require the use of general anesthesia or laparotomy, in fact this method is applicable to many patients with severe liver disease not suitable for it. TIPSS has been studied for the management of variceal bleeding, ascites, hepatic hydrothorax, hepatorenal syndrome, and other types of cirrhosis. However, some drawbacks of the TIPSS, such as shunt stenosis and hepatic encephalopathy, have also been reported in the literature. On the basis of the available evidence and the new epidemiological findings regarding liver disease, the following question may be posed: What is the place of TIPSS in current clinical practice?
Comparative study of clinical efficacy of laparoscopic proximal gastrectomy with double-channel anastomosis and tubular gastroesophageal anastomosis
Authors: Wang Mian , Zhang Li-Li , Wang Gang , Miao Yong-Chang , Zhang Tao , Qiu Lei , Fang Gui-Da , Lu Feng , Xu Da-Lai , Yu Peng
Published: December 2024

BACKGROUND

According to statistics, the incidence of proximal gastric cancer has gradually increased in recent years, posing a serious threat to human health. Tubular gastroesophageal anastomosis and double-channel anastomosis are two relatively mature anti-reflux procedures. A comparison of these two surgical procedures, tubular gastroesophageal anastomosis and double-channel anastomosis, has rarely been reported. Therefore, this study aimed to investigate the effects of these two reconstruction methods on the quality of life of patients with proximal gastric cancer after proximal gastrectomy.

AIM

To compare short-term clinical results of laparoscopic proximal gastrectomy with double-channel anastomosis vs tubular gastric anastomosis.

METHODS

Patients who underwent proximal gastrectomy at our hospital between January 2020 and January 2023 were enrolled in this retrospective cohort study. The patients were divided into an experimental group (double-channel anastomosis, 33 cases) and a control group (tubular gastric anastomosis, 30 cases). Baseline characteristics, surgical data, postoperative morbidities, and postoperative nutrition were recorded.

RESULTS

The differences in baseline data, surgical data, and postoperative complications (20.0% vs 21.2%) were not statistically significant between the two groups. There were no statistically significant differences in the levels of postoperative nutrition indicators between the two groups of patients during the preoperative period and at 3 months postoperatively. In addition, the levels of postoperative nutrition indicators in patients in the experimental group declined significantly less at 6 months and 12 months postoperatively compared with those of the control group (P < 0.05). At 12 months postoperatively, the difference in anastomotic reflux esophagitis between the two groups was statistically significant (P < 0.05) with the experimental group showing less reflux esophagitis.

CONCLUSION

Both double-channel anastomosis and tubular gastric anastomosis after proximal gastrectomy are safe and feasible. Double-channel anastomosis has a better anti-reflux effect and is more beneficial in improving the postoperative nutritional status.
Multiple jejunal diverticula with repeated gastrointestinal bleeding: A case report
Authors: Li Meng-Yun , Han Zhe , Wang Hao , Wang Yuan-Yuan , Zhao Zeng-Ren
Published: December 2024

BACKGROUND

Jejunal diverticula (JD) are rare clinical conditions that are typically incidentally detected and asymptomatic. When acute complications arise, surgical exploration may be necessary for accurate diagnosis and appropriate treatment. In this report, we present a case of multiple JD complicated by gastrointestinal bleeding and review the pathogenesis, diagnosis, and treatment of JD to increase clinician awareness of this condition.

CASE SUMMARY

A 70-year-old male patient with multiple JD presented with repeated massive gastrointestinal bleeding. The patient did not respond to symptomatic conservative treatment. Additional diagnostic investigations, including digestive endoscopy and abdominal angiography, did not reveal any relevant abnormalities. An exploratory laparotomy was subsequently performed, during which a segment of the bowel containing numerous diverticulum-like structures was surgically removed. Following successful discharge from the hospital, the patient did not experience any further episodes of gastrointestinal bleeding during subsequent follow-up.

CONCLUSION

Complications caused by JD are often difficult to diagnose, and surgical exploration is sometimes the most appropriate method.
Multimodal treatment combining neoadjuvant therapy, laparoscopic subtotal distal pancreatectomy and adjuvant therapy for pancreatic neck-body cancer: Case series
Authors: Li Jia , Wang Xi-Tao , Wang Yi , Chen Kang , Li Guo-Guang , Long Yan-Fei , Chen Mei-Fu , Peng Chuang , Liu Yi , Cheng Wei
Published: December 2024

BACKGROUND

Pancreatic cancer involving the pancreas neck and body often invades the retroperitoneal vessels, making its radical resection challenging. Multimodal treatment strategies, including neoadjuvant therapy, surgery, and postoperative adjuvant therapy, are contributing to a paradigm shift in the treatment of pancreatic cancer. This strategy is also promising in the treatment of pancreatic neck-body cancer.

AIM

To evaluate the feasibility and effectiveness of a multimodal strategy for the treatment of borderline/locally advanced pancreatic neck-body cancer.

METHODS

From January 2019 to December 2021, we reviewed the demographic characteristics, neoadjuvant and adjuvant treatment data, intraoperative and postoperative variables, and follow-up outcomes of patients who underwent multimodal treatment for pancreatic neck-body cancer in a prospectively collected database of our hospital. This investigation was reported in line with the Preferred Reporting of Case Series in Surgery criteria.

RESULTS

A total of 11 patients with pancreatic neck-body cancer were included in this study, of whom 6 patients were borderline resectable and 5 were locally advanced. Through multidisciplinary team discussion, all patients received neoadjuvant therapy, of whom 8 (73%) patients achieved a partial response and 3 patients maintained stable disease. After multidisciplinary team reassessment, all patients underwent laparoscopic subtotal distal pancreatectomy and portal vein reconstruction and achieved R0 resection. Postoperatively, two patients (18%) developed ascites, and two patients (18%) developed pancreatic fistulae. The median length of stay of the patients was 11 days (range: 10-15 days). All patients received postoperative adjuvant therapy. During the follow-up, three patients experienced tumor recurrence, with a median disease-free survival time of 13.3 months and a median overall survival time of 20.5 months.

CONCLUSION

A multimodal treatment strategy combining neoadjuvant therapy, laparoscopic subtotal distal pancreatectomy, and adjuvant therapy is safe and feasible in patients with pancreatic neck-body cancer.
Effect of ligamentum teres uteri preservation in laparoscopic high hernia sac ligation in children with indirect inguinal hernia
Authors: Lin Xiao-Qiang , Li Hua-Fang , Lin Yan-Zhu , Chen Wen-You
Published: December 2024

BACKGROUND

Routinely separating the ligamentum teres uteri (LTU) intraoperatively remains an unresolved issue for female children undergoing surgery for indirect inguinal hernia (IIH).

AIM

To identify the effect of LTU preservation in laparoscopic high hernia sac ligation (LHSL) in children with IIH.

METHODS

The participants were 100 female children with unilateral IIH admitted from April 2022 to January 2024 to the Pediatric Surgery Department of Zhangzhou Municipal Hospital of Fujian Province. They were categorized based on LTU retention into the control group (n = 45 cases), which underwent LTU ligation intraoperatively, and the experimental group (55 cases), which had the LTU preserved intraoperatively. All children underwent LHSL.

RESULTS

This study comparatively analyzed the operation time, hospitalization time, blood loss, postoperative recurrence rate, and complications (repeated pain in the inguinal region, foreign body sensation in the inguinal region, bloody exudation at the inguinal incision, and incision infection), which were all comparable between the two groups.

CONCLUSION

The above results indicate that LTU preservation during LHSL exerts certain therapeutic benefits for children with IIH. LTU preservation does not increase hospitalization time, blood loss, postoperative recurrence rate, and complications, which is safe and feasible, compared with conventional LTU ligation. LHSL with LTU preservation should be performed if conditions permit, which is worth popularizing.
A Study of India’s Transition to Electric Mobility and Its Impact on
Associated Partners
Authors: Vashist Devendra , Malik Varun , Pandey Sachchidanand
Published: December 2024

The transition from internal combustion engine (ICE) industry to electric vehicle
(EV) industry has significant financial implications for both the automotive
industry, government, and associated partners. The shift to EVs could lead to
savings in foreign exchange reserves, the creation of new jobs, and a reduction
in greenhouse gas emissions. However, the transition could also result in job
losses in the automobile and its associated manufacturing industry. This study
aims to analyze the impact of this transition on different stakeholders in
India. The study takes into account the different financial aspects that
includes production, technology, government policy, skilling, employability, job
creation, and other associated aspects on Indian economy. For the projected
study different cases were considered with 2030 as the projected year with 30%
EVs. A modest attempt is made to analyze the impact on associated partners. The
findings of the study suggest that the transition to EVs could lead to reduced
imports, job creation in new emerging areas, reduction in emissions, and
enhanced technical and innovation capabilities in the EV sector if collaborative
efforts are there among three major stakeholders, i.e., government, automotive,
and petroleum industry.
GREEN TOURISM DEVELOPMENT SITUATION AND PROSPECTS IN IMERETI REGION
Authors: Khasaia Izolda , Demetradze Tamta
Published: December 2024

Izolda Khasaia
E-mail: izolda.khasaia@atsu.edu.ge
Associate Professor, Akaki Tsereteli State University
Kutaisi, Georgia
https://orcid.org/0000-0002-9689-4277
 
Tamta Demetradze
E-mail: tamta.demetradze@atsu.edu.ge
PhD candidate, Akaki Tsereteli State University
Kutaisi, Georgia
 
Abstract: Green tourism is the business of providing recreation and related services that are not harmful to the environment of a regional area. It promotes environmentally friendly and sustainable practices throughout the tourism value chain and minimizes the negative impacts of tourism on the environment.
The purpose of the presented research is to familiarize with the practice of green tourism development in the Imereti region and determine the existing challenges.
Research has shown that there are many examples in the business sector of combining sustainable practices and modern technologies in the tourism industry.
The paper includes examples of the current practice of green tourism included in the research of various successful businesses in the Imereti region of Georgia (hotel, hotel complex, wine tourism destinations (cellars), administration of protected areas of Imereti caves, cultural tourism facility), which emphasize various aspects of the principles of green tourism.
Small hotels are taking energy-saving measures, including reducing the frequency of towel changes and closing certain parts of the building during off-peak seasons to save energy. However, power outages are a problem because high voltage generators are not environmentally friendly. To solve this problem, there is a growing interest in alternative energy sources such as solar panels.
Small family-run wineries are an example of successful ecotourism through organic viticulture and low-intervention wine production, focused on protecting the environment through waste management. They also offer tourists authentic cuisine, local organic produce and accommodation in a green environment.
It is worth noting the initiative, which includes the strengthening of landslide-prone slopes by planting fruit trees, which naturally stabilizes the soil with roots and prevents environmental degradation.
Creating additional green areas for tourists to relax and enjoy nature is another practice adopted by the respondents. This is in line with the growing emphasis on sustainability and the environment.
The development of green tourism faces many interrelated challenges that require the joint efforts of the government, the private sector and civil society.
Despite the problems related to waste management, wastewater, financial etc. Developing practices and growing awareness among industry representatives indicate a good future for green tourism in Imereti.
Keywords: green tourism, sustainable development, waste management, environmental protection, wine cellars, Imereti
 
JEL classification: Z320
Belgesel Sinema: Suha Arın Sinematografisi
Authors: Avlar Ali
Published: December 2024

Belgesel film, doğal yaşamın gerçekliği içerisinde var olmaktadır. Belgesel filmin senaryosunu hayatın kendisi oluşturmaktadır. Belgeselin belgeye dayalı olması nedeniyle içinde yaşadığımız zaman diliminde meydana gelen olaylar şu an için bir anlam ifade etmiyor olsa bile gelecek için bir belge niteliği taşıyabilir. Belgesel sinemacının ortaya koyduğu çalışmasının başarı olabilmesi için içinde yaşadığı topluma sırtını dönmemeli, içinde yaşadığı çevreyi tanımalı ve gözlemci bir ruha sahip olmalıdır. Her sanatın olduğu gibi belgesel sanatının da bir yaratıcısı ve amacı vardır. Belgesel sanatının yaratıcısı yönetmen amacı ise sanatın sunmuş olduğu kendine has özellikleri kullanarak insanları etkilemek ve ikna etmektir. Belgesel film, toplum yaşamının ve kültürel özelliklerinin belgelenmesini, aktarılmasını ve toplumsal bellek oluşturulmasını sağlamaktadır. Belgesel film yönetmeni aktarmak istediği gerçeği, gerçekliği bozmadan, sinemanın kazandırdığı olanaklardan faydalanarak etkili bir şekilde ortaya koymaya çalışır. Bu bağlamda Türkiye’de belgesel sinemanın önde gelen isimlerinden ve ilk belgesel film yönetmenlerinden biri olan Suha Arın’ın yönetmenliğini yapmış olduğu Safranbolu’da Zaman filminin analiz edilmesi önemlidir. Çalışmanın amacı Suha Arın’ın anlatı yapısını nasıl oluşturduğunu ortaya koymaktır. Bu nedenle çalışmada örneklem olarak seçilen Safranbolu’da Zaman filmi nitel araştırma yöntemiyle incelenmiş ve nitel veri analiz yöntemi olarak da betimsel analiz kullanılmıştır.
Optimizing precision farming: enhancing machine learning efficiency with robust regression techniques in high-dimensional data
Authors: Afouna Nour Hamad Abu , Ali Majid Khan Majahar
Published: December 2024

Smart precision farming leverages IoT, cloud computing, and big data to optimize agricultural productivity, lower costs, and promote sustainability through digitalization and intelligent methodologies. However, it faces challenges such as managing complex variables, addressing multicollinearity, handling outliers, ensuring model robustness, and enhancing accuracy, particularly with small to medium-sized datasets. To overcome these obstacles, reducing retraining time and resolving the complexity issue is essential for improving the machine learning algorithm’s performance, scalability, and efficiency, especially when dealing with large or high-dimensional datasets. In a recent study involving 435 drying parameters and 1,914 observations, two machine learning algorithms - Ridge and Lasso - were employed to analyze and compare the impact of two variable selection techniques, specifically the regularization methods Ridge and Lasso, before and after addressing heterogeneity in highly ranked variables (50, 100, 150, 200, 250, 300). Additionally, robust regression methods such as S, M, MM, M-Hampel, M-Huber, M-Tukey, MM-bisquare, MM-Hampel, and MM-Huber were applied. The results demonstrated that the robust methods, when applied to Ridge and Lasso, achieved the highest efficiency, with the smallest values for MAPE, MSE, SSE, and the highest R2 values, both before and after accounting for heterogeneity. As a result of the study, the best models are the Ridge model with the MM bisquares before heterogeneity, the Ridge model with the MM method after heterogeneity, and the Lasso model with the MM method before heterogeneity and the Lasso model with MM Hampel after heterogeneity.
You Will Recognize Her… About the Transformations of the Female Body in Cinema
Authors: Penner Regina V.
Published: December 2024

The study of female corporality in cinema is relevant in the context of the analysis of contemporary ideas about the body as a cultural and ideological construct. In the con-text of mass visual culture, the female body is often depicted stereotypically, emphasizing either sexualized or vulnerable aspects, which limits the depth of perception of corporality and female identity. The purpose of the article is to identify how cinematic images of the female body serve as a means of conveying cultural and social meanings, as well as to expose the illusory nature of ideas about the female body often created by screen culture. The study applies methods of socio-philosophical, cultural and feminist analysis, as well as the theory of visual media. Particular attention is paid to the concept of the “male gaze” and the fragmentation of corporality, which are used to identify and deconstruct stereotypical images in cinema. One of the key results of the work was the conclusion that the female corporality on screen is often depicted as a visually attractive shell, devoid of deep meaning and authenticity. Cinema represents the body as an object of the viewer's gaze, reinforcing ideological stereotypes and turning the body itself into an instrument of manipulation. The absence of an authentic body leads to a loss of subjectivity, which creates a need for new approaches to visualizing corporeality that can bring the viewer closer to an authentic experience.
PHRASEOLOGY OF KOMAZINI LOCAL SPEECH PATTERN
Authors:   Institut za hrvatski jezik i jezikoslovlje, VUKŠA NAHOD Perina , NAHOD Bruno
Published: December 2024

The present paper uses field research of phrasal corpus of Komazini (Neretva valley) local speech pattern to show the structural and conceptual analysis of phrases used. Special attention is focused on those concepts related to man (his appearance, nature, condition, attitude towards work, movements and interpersonal relations). In the introductory part, phonological features of the researched speech pattern are addressed.
THE PASSION OF CHRIST THEME BY I. A. NENADIĆ IN THE MONTENEGRIN BAROQUE LITERATURE
Authors:   Fakultet za crnogorski jezik i književnost – Cetinje, RADOMAN Aleksandar
Published: December 2024

The literary work of Ivan Antun Nenadić (1723-1784) has still not been fully published, but it can be argued that his more important published works have received adequate literary-historical reception. Given the various designations present in the literature and the genre and style of his poetics, the issue of his poetic background in the paper entitled The Passion of Christ Theme by I. A. Nenadić in the Montenegrin Baroque Literature reveal late Baroque period writing characteristics, implying that the author used transformed genres of medieval poetics, giving them a new form at both, formal and internal level. The author of the study specifically addresses the issue of echo motif in Nenadić’s most important work, a devout tragedy The Passion of Christ Theme, which resulted in findings that point to the relationship towards the wider context of the function and motif of echo in the neighbouring, Dubrovnik and Dalmatian area, as well as to the characteristics of Nenadić’s use of this rhetorical prop. These considerations confirm the unquestionable Nenadić’s belonging to the Baroque style and poetics.
POETIC POSTULATES OF MIDDLE AND YOUNGER GENERATION OF MONTENEGRIN POSTMODERN LYRICISTS
Authors:   Zavod za školstvo Crne Gore, VUČINIĆ-GUJIĆ Anka
Published: December 2024

In this paper, the author notes that ambiguity and numerous contradictions within the postmodern poetics have provided poets with continuous openness to reviewing the reality which can be interpreted only through signs. By avoiding solid canon, except when it comes to aesthetic principles, while accepting the tendencies that have marked the European literature of the postmodern, Montenegrin postmodern lyricists have made significant progress in comparison with their predecessors in terms of inter-textuality, citations and well-blended mythical forms. Invariant units of poetry of middle and young generation of Montenegrin postmodern poets are: avoidance of solid metric organization and rhymes, wondrous poetic images generated through frequent use of metaphors and symbols, with mainly present pessimistic and melanc-holy tone.
BETWEEN FICTION AND REALITY: CHARACTER OF CHRISTOPHER COLUMBUS IN CROATIAN DRAMA
Authors:   Filozofski fakultet u Splitu, ARMANDA ŠUNDOV Lucijana
Published: December 2024

Relying on Nikola Batušić’s text from the Third Program of Croatian Radio from 1993 entitled Three Croatian dramatic Columbuses, the author of this paper attempts to interpret four Croatian dramatic texts whose main character is researcher Christopher Columbus. The works analyzed include a dialogue poem by Junije Palmotić written around 1630 under the name of Kolombo, a drama by Miroslav Krleža from 1918 under the name Kristofor Kolumbo and a drama by Nedjeljko Fabrio from 1968 under the name of Admiral Kristof Kolumbo. Subsequently, Slobodan Šnajder wrote a short drama Dijalektički Anticolumbus which refers directly to Krleža. Analyzing the dramas, the author reveals the way in which the character of Columbus is presented in Croatian literature and reveals symbols that are attached to his character by Croatian writers from the older to the newer literature.
PERFIL EPIDEMIOLÓGICO DE CÂNCER EM CONCEIÇÃO DO COITÉ–BA/BRASIL
Authors: M. Côrtes Lorenna , P. De Oliveira Rosemeire , Hilberto de Oliveira José , De O. C. Neto Antonio , Rodrigues Elielson
Published: December 2024

Introdução: De acordo com a Organização Mundial de Saúde (OMS), até o ano de 2030 em todo o mundo, 27 milhões de pessoas serão acometidas com o Câncer. Segundo o INCA, o Brasil deve registrar mais de 700 mil casos de câncer por ano entre 2024 e 2025. Para a Bahia, o número anual é de 38.840, que totalizam mais 116 mil ocorrências. O câncer é uma doença grave, representa um grande desafio para a saúde pública. Este trabalho pretendeu-se analisar o perfil epidemiológico dos residentes do municipio baiano de Conceição do Coité-Ba/Brasil. Método: Trata-se de um estudo descritivo e retrospectivo com uma abordagem qualiquantitativa. Os dados foram coletados na plataforma DATASUS entre 2013 a 2024. Resultados: O estudo mostrou que as neoplasias mais frequentes em Conceição do Coité-BA, seguem os mesmos padrões de todo o país, contudo as frequencias de pele, útero e tireóide carecem de estudos mais detalhados. Conclusão: que a pesar dos tipos de cânceres com maior incidência estão conforme o esperado, as frequencias de pele podem ser reflexo da principal atividade do municipio que é a cultura do sisal e dever ser melhor investigada. A partir do conhecimento do perfil epidemiológico, sugere-se as autoridades sanitárias realizem políticas públicas de prevenção, diagnóstico e tratamento na regiao do sisal.
SEMIOTICS OF THE POLITICAL ADVERTISEMENT DISCOURSE ANALYSIS IN TRANSLATION
Authors:   Georgian International University Tbilisi, Georgia, Topuria Ekaterine
Published: December 2024

Discourse analysis and the theory of Translation provide a framework for critically analyzing advertisements beyond their surface meanings, revealing the complex ways in which they communicate ideas, values, and desires to audiences. By examining the language, ideology, narrative structures, audience reception, and discursive strategies of advertisements, discourse analysts can uncover deeper insights into their social, cultural, and political significance via the translated text. Dialogue in communication and media studies can be a valuable tool for examining texts of advertisements in English form Georgian and visa versa and understanding the ways in which they construct meaning, persuade audiences, and reflect cultural norms. One of the discourse analysis types involves analyzing the language used in advertisements, as well as the signs and symbols employed. This includes examining the choice of words, slogans, and visual elements such as images, colors, and logos. Semiotics, the study of signs and symbols, helps in understanding how meaning is created and communicated through these elements. This in its way helps to define the concrete means of ironical or paradox forms of expressing politicians in political slogans.
Surface texturing for tribomechanical performance optimisation of epoxy composites reinforced with chemically activated carbon
Authors:   Faculty of Engineering, University of Port Harcourt, Nigeria, Akuwueke Leonard Maduabuchi , Ossia Chinwuba Victor ,   Faculty of Engineering, University of Port Harcourt, Nigeria, Nwosu Harold Ugochukwu ,   Faculty of Engineering, University of Port Harcourt, Nigeria
Published: December 2024

The effects of surface texturing on the tribomechanical properties of epoxy composites reinforced with chemically activated carbon were studied. Activated carbon produced from palm kernel (PKSAC) and coconut shells (CSAC) were composed in three concentrations (XCSAC): 100 vol. % CSAC + 0 vol. % PKSAC, 50 vol. % CSAC + 50 vol. % PKSAC and 0 vol. % CSAC + 100 vol. % PKSAC, three particle sizes (XPS): 60, 105 and 150 μm, three reinforcement amounts (XRW): 4, 6 and 8 wt. %, and used to fabricate cylindrical discs of Ø 50 × 6 mm height with four surface texture geometries. The epoxy/activated carbon composites were experimentally evaluated for tribomechanical performance using Box-Behnken design. Multivariate second-order polynomial models approximated the influence of XCSAC, XPS and XRW on the tribomechanical properties. The aim was to use the property response to determine the effect of texturing on the tribomechanical properties of composites for automobile applications. The maximum tensile strength value was the highest for the untextured surface, followed in descending order by circular, triangular and rectangular surface texture. The maximum compressive strength value was the highest for the untextured surfaces, followed in descending order by triangular, circular and rectangular surface texture. The maximum wear rate value was the highest for the untextured surfaces, followed in descending order by rectangular, circular and triangular surface texture, while the maximum coefficient of friction value was the highest for the circular surface texture, followed in descending order by triangular and rectangular surface texture and untextured surfaces. Texturing surfaces were found to reduce the composites' mechanical properties while decreasing the wear rate and increasing the coefficient of friction.
Assessing the Prognostic Utility of the HALP Score in Breast Cancer and Its Association with Axillary Lymph Node Involvement
Authors: Soomro Rufina
Published: December 2024

Background: The Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score has recently gained fame as a novel prognostic marker for predicting clinical outcomes in different cancers. Data regarding its applicability in breast cancer is rare. This study aimed to evaluate the prognostic utility of the HALP score in breast cancer, specifically its correlation with clinicopathological features and its effectiveness in predicting axillary lymph node involvement.

Methods: This cross-sectional study was performed in the Breast Surgery Unit, Liaquat National Hospital, Pakistan during Jan-Sep 2023. HALP score was calculated in patients who planned to undergo surgery for breast cancer. Included in the study were 180 patients who underwent surgical treatment for breast cancer. HALP values were obtained by taking the product of hemoglobin, albumin, and lymphocytes and dividing it by the platelet count. The Area Under the Curve (AUC) was calculated to determine the predictive ability of the HALP score. The young index was computed. Two groups were formed using the threshold value and compared using the Chi-square of the Fisher exact test.

Results: 180 patients were studied with a median age of 53.5 (IQR=22-85) years. Lymph node involvement was seen in 32.2% of patients. Median HALP score was 5.7 (IQR=4-7.2). The receiver operative characteristic curve showed an AUC of 0.544 (p=0.338). Youden index showed 5.95 to be the cut-off value. 53.3% of patients had a HALP score of <5.95. None of the patients’ features were found to be significantly different between those with HALP scores of <5.95 and ≥5.95.

Conclusion: The study did not find a link between the HALP score and the clinicopathological characteristics of breast cancer. However, younger patients and those with positive lymph nodes tend to have higher HALP scores.
Leveraging AI and BDA for enhanced supply chain visibility and resilience in the US: a systematic literature review
Authors: Fesobi Bolatito Omojibola , Ogungbeje Olusola , Fesobi Moyosoreoluwa Abiose
Published: December 2024

The advancements in technology over the past quarter-century have yielded significant transformations in supply chain management, alongside several other sectors. The utilization of Artificial Intelligence (AI) and Big Data Analytics (BDA) has the capacity to greatly enhance the resilience of supply networks and enable more efficient management of resources within the supply chain. The advancements in AI and BDA have brought about significant transformations in the operational practices related to supply chain resilience, making them the forefront of these innovations.  It is vital to elucidate the correlation between AI, BDA and supply chain resilience in order to comprehend the manner in which these transformations manifest themselves within this domain. The integration of AI and BDA technologies into supply chain management has emerged as a crucial avenue for enhancing efficiency, agility, and responsiveness in modern business operations. The objective of this study is to explore the benefits of AI and BDA in boosting supply chain resilience and visibility many. The researchers employed the Kitchenham guidelines to conduct a systematic literature review. The investigation is carried out utilizing online scholarly database systems, yielding a total of 207 initial publications, which are further narrowed down to 30 published studies spanning the period from 2013 to 2023. The research paper could be of interest to pertinent players in the business sector due to its provision of a comprehensive examination of the potential benefits associated with AI and BDA in the context of supply chain resilience and visibility.
Değişen ve Gelişen Dünya: Yapay Zeka ve Metaverse Evreninde Sağlık Hizmetleri
Authors: Çelik Bekleviç Arzum , Sağır Demet
Published: December 2024

Dünya çapında sağlık hizmetlerine olan ihtiyacın artması; nüfus artışı, salgın hastalıklar, savaşlar ve doğal afetlerin bir sonucudur. Hastalıkların değişen doğası ve artan hasta sayısı, hastanelerdeki iş gücünün etkin kullanımını engellemektedir. Yeterli sağlık personelinin bulunmaması, verimli kaynak kullanımına duyulan ihtiyaç ve bireylerin birçok hizmete konfor alanlarından çıkmadan erişme isteği, tıpta yapay zekâ (AI) ve metaverse kullanımını bir zorunluluk haline getirmiştir. Ülkemizde ve tüm dünya ülkelerinde hastalar ilk olarak birinci basamak sağlık hizmeti sunulan merkezlere başvurmaktadırlar. Burada ön tanısı konulan hastalara ya bir tedavi planı oluşturulur ya da bir üst basamağa sevki planlanır. Yoğun hasta talebi bu kurumlarda veri artışına neden olarak verilerin saklanması ve güvenliği gibi hususlarda sıkıntılara neden olmaktadır. Bu nedenle sıklıkla yapay zekâ uygulamalarından yararlanılmakta ve hasta kayıtları sanal depolarda korunmaya çalışılmaktadır. Böylece amaç hastanın verilerine daha kolay ulaşılmasını sağlamaktır. Bu bağlamda tüm dünya ülkelerine bakıldığında hastaların ihtiyaçlarına istinaden, yapay zekâ uygulamaları ve metaverse evreninde sağlık hizmetlerini kolaylaştırıcı çeşitli modellemeler yapılmıştır. Özellikle onkolojik hastalıkları tanılama, kanser tedavilerinin oluşturulması, üç boyutlu görseller ile kullanılarak cerrahi işlemler öncesinde planlama yapılması ve anatomik kesitlerin çıkarılması gibi uygulamalar bu modellemelere örnek olarak verilebilir. Mevcut uygulamaların yeni bir sağlık kültürü oluşturup oluşturamayacağı, birinci basamak sağlık hizmetlerinin bu teknolojilerle verilip verilemeyeceği, doğru teşhis ve tedavi seçeneklerinin sağlanıp sağlanamayacağı, bu teknolojilerin sağlık sistemine entegrasyonunun yararları ve dezavantajlarının neler olduğu gibi sorular akla gelmektedir. Bu derleme, yapay zekâ uygulamalarını ve meta veri tabanını tanımlamayı ve çeşitli uygulamaların sağlık sistemi üzerindeki etkilerini değerlendirmeyi amaçlamaktadır.
Evaluasi kualitas Evaluasi Kualitas Aplikasi Digital Korlantas Polri guna Mendukung Tugas Kepolisian dalam Rangka Penguatan Pelayanan Publik
Authors: Raslin Harvin
Published: December 2024

Transformasi menuju Polri Presisi merupakan program prioritas utama Kapolri Jenderal Polisi Drs. Listyo Sigit Prabowo, M.Si. untuk memodernisasi sarana dan prasarana pelayanan publik guna memudahkan akses pelayanan masyarakat. Salahsatunya Korps Lalu Lintas (Korlantas) Polri telah meluncurkan layanan aplikasi digital, yakni SIM Nasional Presisi (SINAR), pembayaran pajak kendaraan di Samsat Digital Nasional (SIGNAL), Electronic Traffic Law Enforcement (ETLE), dan Integrated Road Safety Management (IRSMS) untuk pemantauan kecelakaan Lalu Lintas. Penelitian ini bertujuan mengevaluasi aplikasi digital Korlantas Polri (SINAR, SIGNAL, ETLE, dan IRSMS) agar memenuhi standar aplikasi Polri yang diamanatkan Master Plan Teknologi Informasi dan Komunikasi Polri sesuai Keputusan Kapolri Nomor 704/V/2018 serta sejauhmana mampu memberikan pelayanan cepat, mudah, dan transparan juga melindungi data pribadi pengguna. Metode penelitian menggunakan pendekatan kualitatif dan kuantitatif dengan pengumpulan data melalui wawancara, observasi, dan kuesioner. Hasil penelitian menunjukkan aplikasi digital Korlantas Polri telah berkembang, tetapi perlu perbaikan. Hosting aplikasi di data center swasta, integrasi belum optimal, proses pengolahan data kurang efisien, dan tata kelola keamanan masih perlu diperbaiki merupakan beberapa aspek yang perlu ditindaklanjuti. Secara kuantitatif, aplikasi digital Korlantas Polri dinilai bermanfaat oleh masyarakat, tetapi sebagian besar tidak sepenuhnya mengenal fitur-fitur seperti SINAR, SIGNAL, dan ETLE. Sehingga perlunya sosialisasi yang lebih luas terlihat dari segi kualitatif. Untuk Fitur layanan IRSMS dinilai sangat efektif dalam memberikan pelayanan masyarakat. Secara keseluruhan, evaluasi ini memberikan wawasan penting untuk meningkatkan kualitas aplikasi digital Korlantas Polri agar lebih mendukung tugas kepolisian dalam memberikan pelayanan masyarakat.
Radiation Diagnosis of the Right Kidney Calyx Diverticulum Complicated by Urolithiasis (clinical case report)
Authors: Pavlov Evgeny N. , Diomidova Valentina N. , Prosyannikov Mikhail Yu. , Voitko Dmitry A.
Published: December 2024

Renal calyx diverticulum is a cystic cavity located within the kidney, lined with transitional epithelium from the inside and communicating with the calyx or with the renal pelvis through a narrow neck. Renal calyx diverticulum is a congenital pathology of the kidney, diagnosed mainly by ultrasound, computer or magnetic resonance imaging of the abdominal organs, kidneys and the retroperitoneal space. The purpose of this work was to demonstrate a case from the clinical practice of primary radiation diagnosis and differentiation of diverticulum of the right kidney calyx complicated by urolithiasis in a young woman of reproductive age. Subsequently, a successful surgical excision of the kidney calyx diverticulum was performed. The presented clinical example confirms that the use of modern methods of radiation diagnostics (ultrasound, native and intravenous contrast computed tomography) and implementation of a diagnostic algorithm for suspected diverticula of the renal calyx against the background of urolithiasis made it possible to avoid errors and contributed to the successful recuperation of the patient.
Lipid peroxidation and thiol/disulfide homeostasis in cattle with trichophytosis
Authors: Bölükbaşı Lale , Merhan Oğuz
Published: December 2024

The aim of this study was to determine thiol/disulfide homeostasis in cattle with trichophytosis and to determine the changes in malondialdehyde (MDA), catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px=GPx) levels due to the disease. 15 cattle with trichophytosis and 15 healthy cattle in the control group constituted the material of the study. Blood samples were taken from the jugular vein of the animals in tubes with and without anticoagulant. MDA, CAT, SOD, total thiol, native thiol analyses were performed in serum and GSH-Px analyses were performed in plasma. It was determined that total thiol, native thiol and native thiol/total thiol levels among biochemical parameters in cattle with trichophytosis decreased statistically significantly. It was determined that disulfide/native thiol and disulfide/total thiol levels increased statistically compared to the control group. Although the disulfide level increased compared to the control group, it was not statistically significant. In addition, it was determined that MDA level increased compared to the control group, CAT, SOD and GSH-Px levels decreased statistically significantly compared to the control group. In conclusion, the findings obtained from the study showed that trichophytosis causes oxidative stress in cattle, and the use of oxidative stress markers, especially thiol/disulfide homeostasis markers, would contribute to the pathogenesis of trichophytosis.
Determination of Oxidative Stress and Sialic Acid Levels in Cattle Infected with Hydatid Cyst
Authors: Doğan Merve , Bozukluhan Kadir
Published: December 2024

The aim of the study was to determine oxidative stress and sialic acid levels in cattle with hydatid cysts. In the study, 15 hydatid cyst infected and 15 healthy cattle were used. Total sialic acid (TSA), lipid-bound sialic acid (LBSA), protein-bound sialic acid (PBSA), nitric oxide (NO) and malondialdehyde (MDA) levels were determined colorimetrically in the animals. It was determined that TSA, LBSA, NO, and MDA levels were increased in the cattle with hydatid cysts compared to the control group, while PBSA level increased but was statistically insignificant. In conclusion, it was concluded that oxidative stress occurs in the cattle infected with hydatid cyst and TSA can be used as an indicator in the diagnosis of the disease.
HORASAN’IN COĞRAFİ SINIRLARINI BELİRLEME VE HARİTALANDIRMA: ORTAÇAĞ’DA BİR BÖLGENİN SINIRLARINI ÇİZEBİLMENİN İMKANLARI VE SINIRLILIKLARI
Authors: Arifoğlu Yunus
Published: December 2024

Coğrafya gerek fiziki yapısı ve gerekse iklim koşulları dolayısıyla üzerinde barındırdığı insanı ve dolayısıyla toplumu biçimlendiren en önemli unsurların başında gelmektedir. İbn Haldun’un coğrafyanın tarih üzerinde etkisine dair teorisi aşikardır. Modern tarihçilerden Frye, klan, aşiret, kabile askeri ve diğer toplumsal örgütlemelerin coğrafyaya göre şekillendiğini ifade etmektedir. Tarih bir mekan üzerinde seyrettiğinden dolayı tarihsel coğrafya çalışmaları da bu minvalde önem kazanmaktadır. Horasan bölgesinin Ortaçağ’daki coğrafi sınırlarını belirlemek ve münasebette bulunduğu komşu bölgelerini tespit etmek, önemini anlamayı kolaylaştırmaktadır. Horasan’ın sınırları etrafında yer alan bölgeler baz alınarak kabaca belirlenebilir. Nitekim şimdiye kadar yapılan sınır tasnifleri de buna binaen oluşturulmuştur. Ancak bu tasniflerde sınırların net olarak nerede başlayıp nerede bittiği de belli değildir. Bu ihtiyaca cevaben yapılan bu çalışmada, Horasan’ın sınırları hem daha net hâle gelecek hem de bu minvalde bölgenin bir haritası hazırlanacaktır. Horasan’ın sınırları ve yerleşim birimlerinin yanı sıra çevresinde yer alan bölgelerin de haritaları yapılarak bölgenin konumu daha iyi şekilde ortaya çıkarılacaktır.
TEK PARTİ DÖNEMİ’NDE İZMİR’DE CUMHURİYET HALK PARTİSİ: MÜFETTİŞLİK RAPORLARI ÜZERİNDEN YENİ BİR DEĞERLENDİRME (1936-1937)
Authors: Selçuk Fatih
Published: December 2024

Osmanlı Devleti’nden Türkiye Cumhuriyeti’ne uzanan tarihsel seyirde daima önemli bir şehir olarak bilinen İzmir, bu önemini Cumhuriyet döneminde de sürdürmüştür. Cumhuriyet’in sembol şehirlerinden olan İzmir gerek nüfusu gerekse diğer özellikleri bakımından Türkiye’nin diğer illerine nazaran farklı bir yerde durmakta, çoğunlukla İstanbul’un ardından gelmektedir. Bu durumda, Tek Parti Dönemi siyasetinde İzmir ayrı bir öneme sahip olmuştur. İzmir’in bu özelliği, 1930 yılında Atatürk’ün inisiyatifi ile girişilen Serbest Cumhuriyet Fırkası (SCF) tecrübesinde de açık bir şekilde görülmüştür. Cumhuriyet Halk Partisi (CHP), ilk defa bu tecrübe ile taşradaki gücünün ne denli zayıf ve kırılgan olduğunu fark etmiş ve bundan sonraki süreç bu zayıflığa karşı düşünülen çareler ekseninde ilerlemiştir. Mevcut literatür, genel olarak CHP’nin 1930’lardan 1940’lara giden tek partili süreçte taşradaki zayıflığının büyük oranda sürdüğüne işaret etmektedir. İzmir üzerine daha önce yapılan çalışmalarda ise bu tür bir hipotez öne sürülmemiştir. Bu makalede, 1936 ve 1937 yıllarında CHP’li iki Milletvekili ve Parti Müfettişi tarafından İzmir’deki CHP teşkilatları hakkında hazırlanan raporlar üzerinden, CHP’nin taşradaki konumuna İzmir penceresinden bakılmaktadır. Makalede İzmir üzerinden elde edilen bulgular, CHP’nin taşrada genel olarak zayıf, etkisiz, denetimsiz ve büyük oranda devletin himayesi altında bulunan bir siyasi parti özelliği gösterdiği şeklindedir. Bu bakımdan makale, tek parti döneminde CHP’nin totaliter veya otoriter bir tek parti olduğu yönündeki tezlerin partinin teşkilat olarak İzmir’de arz ettiği manzara üzerinden tartışmaya açılabileceğini öne sürmektedir.
INTERVIEW: ON ENVIRONMENTAL HISTORY WITH ALAN MIKHAIL
Authors: Avcı Dilara
Published: December 2024

Alan Mikhail is the author of five books and editor of another. His work has helped to establish the field of Middle East environmental history, positioned the Ottoman Empire at the center of global early modern history, and creatively scrutinized the place of the archive in the making of past and present. He is currently working on the intertwined histories of Islam and colonial America.
IS1600 Eğik Makas Yağ Tankı Sirkülasyon Pompası Destek Sacı Isıl Analizi ve Yanıt Yüzey Yöntemi ile Optimizasyonu
Authors: Öğüçlü Özer , Yıldırım Çağatay Yeldar
Published: December 2024

Bu çalışmada, IS1600 Eğik Makasın yağ tankı sirkülasyon pompası destek sacının ısıl ve statik koşullarının parametrik optimizasyonu incelenmiştir. Bu desteğin üç boyutlu katı modeli Sonlu Eleman Analizi için ANSYS’e yüklenmiştir. AYMAS Geri Dönüşüm Makineleri tarafından üretilen Eğik Makas’ın yağ tankı sirkülasyon pompası destek sacının, sıcaklık, ısı taşınımı ve kuvvet değerleri kullanılarak Von-Mises Gerilmesi ve Toplam Şekil Değiştirmesini hesaplamak üzere ANSYS’te modeli geliştirilmiştir. Sıcaklık ve kuvvet değerleri bu parametrik optimizasyonun giriş parametreleri olarak belirlenirken, von-Mises Gerilmesi ve Toplam Şekil Değiştirmesi çıktı sonuçları olarak belirlenmiştir. Bu değişkenler kullanılarak Yanıt Yüzeyi Yöntemi ile ANSYS üzerinden çoklu optimizasyon gerçekleştirilmiştir. Sıcaklık değerleri; düşük sıcaklıkların sebep olduğu yüksek viskoziteyi önlemek için 35˚C ile uygun çalışma koşullarını sağlamak için eğik makasın çalışmasının durduğu sıcaklık olan 55˚C ile sınırlandırılmıştır. Bu analizde yağ tankı soğutma sisteminin en az kullanımı hedeflenmiştir. Hasara sebep olmamak için destek sacı malzemesi olan AISI 316 çelik malzemesinin akma mukavemeti sınırı geçilmemiştir. Kuvvet değerleri yağ tankının boş ve dolu ağırlığına göre sınırlandırılmıştır. Motor ve pompanın toplam ağırlığı olan 45 kg, yağ tankının doluluk oranına göre değişip en fazla 48 kg değerine ulaşmaktadır. Sirkülasyon pompasındaki hidrolik yağ miktarının sebep olduğu en yüksek ağırlık hedef olarak belirlenmiştir. Bu çalışma sonucunda en uygun sıcaklık ve kuvvet değerleri bulunmaktadır. Bu değerler en yüksek hidrolik yağ ağırlığı ve en düşük sıcaklığa ulaşmak adına 35,006 ˚C ve 473,5 N olarak saptanmıştır.
A Review on the Antidiabetic Potential of Saffron in the Treatment of Type 2 Diabetes Mellitus and Its Research Methodologies
Authors: Sazlı Nil , Karataş Deniz
Published: December 2024

This study is a review of the antidiabetic potential of the Saffron plant in the treatment of Type 2 Diabetes and research methodologies. The experimental design of this project study aimed to obtain crocin from the saffron plant. Crocin is considered a potential natural drug agent thanks to its high antioxidant and antidiabetic properties. However, in order to obtain the highest yield of crocin in obtaining this natural agent, it is very important to ensure optimization by selecting the right extraction techniques, phenolic content, antioxidant and antidiabetic analyses. In this project, it was aimed to apply extraction techniques under appropriate conditions to obtain crocin from the Crocus sativus plant, also known as saffron. In addition, an experimental design was created to apply HPLC to obtain high purity of crocin, TPC analysis to determine total phenolic content, ORAC and DPPH analyses to determine antioxidant capacity, and α-Amylase Inhibition Test and α-Glucosidase Inhibition Test techniques to determine antidiabetic potential. Once the desired results are achieved, experimental studies will be initiated to develop crocin into a natural market drug.
RELIGIOSITY AMONG BOSNIAN YOUTH – ATTITUDES TOWARDS ISLAM AND PRACTICAL WORSHIPPING OF IT
Authors: Delić Haris
Published: December 2024

Interest in individuals’ religious beliefs has a long tradition in philosophy, sociology and psychology and attempts are made to understand the spiritual and physical in humans. This quantitative study investigates the religiosity of young people, primary and secondary school students, in Bosnia and Herzegovina (henceforth BH) and their practical manifestation of religious activities. The results indicate that the Bosnian primary and high school students are not largely religious and their religiosity is not largely expressed in their practical performance of religious duties, such as praying, reading a Holy book and visiting a mosque. Moreover, the research points out that young people in BH are quite religious when it comes to external exposure to religion and a little less when it comes to the practical implementation of religious regulations that are mandatory in Islam. Friday prayer for men is a religious obligation that is taken more seriously and performed than other daily prayers that are also obligatory. This research contributes to a clearer insight into the practical religiosity of young people in BiH and helps in understanding the priorities for improving and increasing the religiosity of young people. Also, this work can serve as a basis for other more comprehensive research in this field.