bluuebunny/crossref_metadata_2025 huggingface dataset:
Inovasi Alat Ukur Kuat Jepit Penambat Rel Untuk Pengujian dan Perawatan Jalur Kereta Api
Authors: Saputra Afnan Zidan , Iqbal Muhammad , Prihatanto Rusman , Aghastya Adya
Published: August 2024

Railway fastening systems treatment and testing need assistance to save time and energy. The first railway fastening system clamping force measuring tools could measure the E-Clip fastening system. Excessive of the steel plate, the maximum height is 850 mm, and the weight reached 18 kg. The first-generation tools are designed to make mobility with the tools harder permanently. From this generation, railway fastening system clamping force measuring tools will be upgraded to more straightforward and more effective railway fastening system clamping force tools. The tools-making steps begin with the design process, which includes making all tool components, assembling them, and testing the tool's function at the Madiun Station emplacement. The tool testing results in the tool's function being according to the plan. The railway fastening system testing data supports it. The tools were also already capable of testing the E-Clip and DE-Clip railway fastening systems. 
ABSTRAK
Perawatan dan pengujian penambat memerlukan alat bantu untuk menghemat waktu dan tenaga. Alat ukur kuat jepit penambat rel kereta api generasi pertama digunakan untuk mengukur kuat jepit penambat E-Clip. Pelat besi yang berlebihan, tinggi maksimal alat 850 mm dan berat alat mencapai 18 kg. Alat generasi pertama didesain secara tetap membuat mobilisasi alat tidak mudah. Dari alat ukur kuat jepit penambat generasi pertama akan dilakukan inovasi agar alat ukur kuat jepit penambat mudah dan praktis. Tahapan pembuatan alat dimulai dengan proses desain, pembuatan semua komponen alat, perakitan dan uji fungsi alat yang dilakukan di emplasemen Stasiun Madiun. Dari hasil uji yang dilakukan terhadap alat didapatkan hasil bahwa fungsi alat telah sesuai dengan sesuai dengan rencana. Hal tersebut juga didukung oleh data hasil pengujian kuat jepit penambat. Alat juga telah mampu digunakan dalam pengujian penambat E-Clip dan DE-Clip.
The Effect of Using Podcast on Listening Achievement of the Eighth Grade Students of Junior High School
Authors: Dewayani Viandra Yashinta , Tasnim Zakiyah , Hudori Rizki Febri Andika
Published: August 2024

This study was conducted to identify the effect of using Podcast on listening achievement of the eighth grade students of Junior High School. Based on the preliminary study, it was known that the eighth grade students in one of the junior high school in Situbondo had never used Podcast as a medium of learning listening skill and the teacher often used audio from the internet to teach listening skill. This study applied quantitative method using quasi-experimental with post-test only design. The two classes at that school were chosen as participants for this research, one class belonged to experimental group and the other belong to control group. The students in experimental group were taught listening skill by using Podcast as a medium of learning, while the students belonged to control group were taught by listening to the teacher read the text. The data were analyzed by using Independent Sample t-test formula in SPSS. The results indicated that there was a significant effect of using Podcast on listening achievement of the eight grade students. It was proven that the significant value (2-tailed) was 0.001 and it was lower than 0.05.
Writing Assessment Methods Utilized by Senior High School English Teacher in Jember
Authors: Megawati Enny , Ariyanto Sugeng , Suharjito Bambang
Published: August 2024

This research was aimed at writing assessment methods utilized by senior high school English teacher in Jember. This research applied qualitative method with grade eleven of English teacher as the research participants. The data were analyzed using thematic analysis to know the assessment  methods employed by the senior high school English teacher. The result of this research shows that the teacher used process assessment and product assessment to assess students’ writing.
A hazai közlekedés- és szállításstatisztika történeti áttekintése – II. rész
Authors: Máténé Bella Klaudia , Lovászné Skach Edit
Published: August 2024

Tanulmányunkban ismertetjük, hogyan alakult az elmúlt száz évben az áru- és személyszállítás egyes módozatainak, valamint a postai szolgáltatásnak a teljesítménye és hogyan változott az egyes járművek állománya. A technikai fejlődés és a módszertani változások jelentősen befolyásolták a szállításstatisztika egyes területeinek mérését és publikálását. A Magyar statisztikai évkönyvek adatainak kigyűjtése és feldolgozása alapján kijelenthetjük, hogy a naturális mérőszámok képesek a hosszú távú tendenciák megragadására, és jól jellemzik az egyes korszakok közlekedéspolitikai döntéseit, valamint a gazdaság konjunktúraciklusait.
O uso da ferramenta ChatGPT no suporte à educação e à produção acadêmica
Authors: Celestino Marcelo Salvador , Valente Vânia Cristina Pires Nogueira
Published: August 2024

Este artigo visa identificar a aplicabilidade, os benefícios e as implicações do ChatGPT, uma ferramenta de Inteligência Artificial (IA), na área da educação e da pesquisa acadêmica. Foram realizados testes observacionais e uma revisão integrativa da literatura mais recente (2023). A literatura aponta que o ChatGPT pode ser aplicado em diversos contextos de ensino e de aprendizagem, estimulando o desenvolvimento autônomo dos alunos e auxiliando os docentes em suas práticas. Na área médica, a ferramenta contribui para a categorização de dados e melhora a comunicação com o paciente; na área odontológica, é sugerida a atualização do currículo para contemplar o uso de ferramentas de IA, embora ela possa produzir respostas diferentes para a mesma pergunta e indicar referências inexistentes. Apesar das falhas, consideramos o uso da ferramenta pertinente para o suporte às práticas de ensino, aprendizagem e produção científica, mas isso demanda uma discussão crítica e reflexiva entre alunos, professores e instituições, a fim de garantir a integridade acadêmica.
PNEUMONIA CASES AMONG TODDLERS BASED ON EXCLUSIVE BREASTFEEDING COVERAGE, UNDERNUTRITION STATUS, AND POPULATION DENSITY IN SIDOARJO REGENCY IN 2019, 2020, AND 2021
Authors: Wigunawanti Rezandra Anggita , Astutik Erni , Khan Rukhsana
Published: August 2024

Introduction: Pneumonia is the leading infectious cause of death among children worldwide accounting for 14% of all under-five deaths. Sidoarjo Regency has the highest incidence of toddlers with pneumonia in East Java. Aims: This study aimed to map and analyze the distribution of pneumonia cases among toddlers in the Sidoarjo Regency based on the risk factors of exclusive breastfeeding coverage, lack of nutrition status, and population density. Methods: This research was a descriptive study using secondary data obtained from the Sidoarjo Regency Health Profile in 2019, 2020, and 2021. This study’s analysis unit included all 18 sub-districts in Sidoarjo Regency. Mapping was done using QGIS software version 3.10, “A Coruña.” Results: The findings showed that the Waru Sub-district was vulnerable to the incidence of pneumonia in toddlers because, apart from consistently having a high prevalence of cases over the last three years, it was also accompanied by high-risk factors, including low coverage of exclusive breastfeeding, high incidence of undernourished toddlers, and high population density. Conclusions: It can be concluded that intervention activities such as socializing and advocating programs of exclusive breastfeeding and balanced toddler nutrition with PMT and immunization are better prioritized in Waru Sub-district.
Pre-exposure Prophylaxis (PrEP) Acceptance among Men Who Have Sex with Men (MSM) and Transgender Women (TGW) in Malaysia: An Analysis from the Integrated Biological and Behavioural Surveillance (IBBS) Survey 2022
Authors: Mohamad Yadzir Zailatul Hani , Ramly Mazliza , Suleiman Anita
Published: August 2024

Background: The pre-emptive use of antiretroviral drugs, known as pre-exposure prophylaxis (PrEP), reduces the risk of contracting HIV if exposed to the virus. The aim of this study was to assess the acceptance of PrEP among MSM and TGW in Malaysia.
Methods: Respondent-driven sampling (RDS) method was used to conduct the IBBS survey between July and December 2022.
Results: Overall, 957 MSM and 504 TGW participated in the study. A total of 78.6% of MSM and 49.4% of TGW had heard about PrEP. A higher percentage of MSM (11.8%) reported using PrEP in the past 12 months, compared to 8.0% TGW. Among respondents, more MSM (57.6%) were interested in taking PrEP in the future than TGW (29.3%). Most respondents (72.5% MSM and 94.0% TGW) prefer condom over PrEP as HIV prevention.
Conclusion: In Malaysia, MSM and TGW still have a low level of acceptance for PrEP. Thus, more initiatives are needed to raise awareness about taking PrEP as a preventive measure.
Does Covid-19 pandemic influence the sustainability of health insurance membership among informal workers in Indonesia?
Authors: Aji Budi , Rachmatika Hasna Tri , Maharani Afrina , Intiasari Arih Diyaning , Anandari Dian , Malik Ahmad Azam
Published: August 2024

Background This study aims to find out the impact felt by informal sector workers due to the Covid-19 pandemic and their efforts to maintain the membership of the NHI program.
Methods This was qualitative research with a case study approach. Eight study participants had been selected for this study. All interviews then transcribing verbatim for further data analysis. The analysis was conducted by using thematic networks approach.
Results There were four themes emerged from the analysis. The themes covering issue about: i) the influence of the Covid-19 pandemic on the informal sector; ii) coping strategies for maintaining NHI premium payment; iii) the role of social capital for supporting informal workers during Covid-19 pandemic; and iv) policy recommendation for protecting the informal sector for maintaining NHI membership.
Conclusions This study highlights the strategic position of cooperatives in supporting their members from the burden of NHI premium payment. Government is needed to support the informal workers product so can improve the economic condition these such population.
Prevalence and Factors Associated with Neonatal Death among Neonates referred to Neonatal Intensive Care Unit from an Urban high-density community of Lusaka, Zambia
Authors: Napanje Chomba , Sampa Mutale , Makasa Musonda , Jacobs Choolwe
Published: August 2024

Background: The first month of life is the most vulnerable period of child survival. Globally the neonatal period accounted for nearly half (47 per cent) of all under-five deaths that occurred in 2022. Factors associated with neonatal death vary between environments and are essentially not well understood. This study aimed to investigate the prevalence and factors associated with neonatal death among neonates born at Kanyama first level hospital, located in an urban high-density community and referred to University Teaching Hospital (UTH)- Neonatal Intensive Care Unit (NICU).
Methods: A cross-sectional study was conducted in January and February 2023 through data extraction from registers and medical files on prevalence and factors associated with neonatal death. Pearson’s Chi square, fisher’s exact test and multiple logistic regression were conducted using the STATA version 14.2. 205 medical records were selected for the study using Cochrane (1963) formula to calculate a minimum sample size of 104.
Results: The study population comprised neonates born at Kanyama first level hospital in 2021 and 2022 of which 38.05% were female, 61.95% were male, 60% were born at full term and 40% were born at pre-term. Factors associated with neonatal death were labour complications (AOR: 3.46, p=0.039), conditions requiring special attention such as preeclampsia (AOR: 20.4, p=0.001), concerning Apgar score at one minute (AOR=4.50, p=0.014) and pre-term at birth (AOR=7.50, p<0.0001).
Conclusion: The prevalence of neonatal death was found to be high and the associated factors included; labour complications, condition requiring special attention, Apgar score at one minute and term at birth. Therefore, neonatal survival should be prioritized through pregnancy monitoring, quality antenatal and Emergency Obstetric and Neonatal Care (EmONC) training to improve response interventions in the event of complications.
Keywords: neonatal mortality, urban high-density community, factors associated, neonatal intensive care unit
Literature Review : Determinant of Latent Tuberculosis Infection (LTBI) in Developing Country
Authors: Radi Radi , Firdaus Dwiyan Maharani Mutiara
Published: August 2024

Background: The problem of TB in Indonesia is increasingly worrying considering that Indonesia is the second country with the most TB cases in the world. Serious efforts are needed to break the chain of TB transmission as early as possible by focusing on preventing risk factors for transmission. TB transmission often occurs within the family, the vulnerable group being infected with TB who live in the same house as TB sufferers. The study aims to know the determinants of latent TB infection in children under 15 years old and adults in developing countries.
Method: This study used the literature review method by collecting journals from Google Scholar, PubMed, and ScienceDirect. Data collection using keywords Risk Factors AND ILTB AND Developing Country. The results of the livelihood obtained a total of 125 articles which were then carefully selected so that 8 of the most relevant articles were obtained for article review.
Results: The research results show that the determinants of ILTB infection are individual factors in the form of history of BCG vaccination, gender, age, history of contact with TB patients, marital status, duration of work, and protozoan infection. The second factor is socioeconomic factors in the form of home ownership, poverty and employment. The third factor is behavior which includes the habit of sleeping in the same room, smoking, sharing needles, and keeping animals at home.
Conclusions: The determinants of ILTB infection are individual, behavioral and socioeconomic factors
Keywords: Latent TB, Risk Factor, Developing Country
Authors: Sudarmaji Arief , Margiwiyatno Agus , Siswantoro Siswantoro , Masrukhi Masrukhi , Wijaya Krissandi , Kuncoro Purwoko Hari , Ropiudin Ropiudin , Mustofa Asna , Sulistyo Susanto Budi , Arsil Poppy , Ritonga Abdul Mukhlis , Irawadi Irawadi
Published: August 2024

Kesediaan air yang tepat dan terukur merupakan aspek penting untuk pertumbuhan tanaman yang optimal. Perlu dilakukan pemantauan kelembaban tanah secara kontinyu sebagai dasar saat penyiraman. Makalah ini menyajikan rancangbangun sistem pengukuran kelembaban tanah dan pengujian sensor kelembaban tanah tipe kapasitif untuk memperoleh model kalibrasi pada beragam jenis tanah. Sistem pengukuran berbasiss mikrokontroler Arduino-Mega yang terdiri dari sensor kelembaban tanah, modul pewaktu, modul kartu memori, keypad, LCD, dan aktuator irigasi. Pada penelitian ini diujikan enam sensor kapasitif tanah (capacitive soil moisture) pada dua jenis tanah, yaitu tanah pasir, dan tanah organik. Tanah pasir berasal dari pesisir pantai di Desa Adipala Kabupaten Cilacap dan tanah organik berasal dari lahan kering di Desa Kedungrandu Kabupaten Banyumas. Proses kalibrasi didasarkan pada tegangan sensor kelembaban tanah kapasitif (V) dan nilai kadar air tanah (KA) yang ditentukan menggunakan metode Gravimetri. Model kalibrasi yang diperoleh untuk masing-masing tanah yaitu KA = 34.23 x V2  -182.84 x V + 249.45 (tanah pasir) dan KA = 2389 x V2 - 9252.6 x V + 9012.9 (tanah organik). Nilai kelembaban tanah, data waktu, dan status irigasi disimpan dalam kartu memori
Penguatan Peran Posyandu Lansia Melalui Case Study dan Alih Teknologi untuk Meningkatkan Derajat Kesehatan Lanjut Usia
Authors: . Saryono , . Heryanto , Sumeru Anas
Published: August 2024

Gangguan kesehatan pada lanjut usia umumnya terjadi akibat kemunduran fungsi organ. Kegagalan fungsi satu organ akan berdampak pada organ yang lain misalnya pada intake makanan yang menurun, aktivitas yang terbatas dan menurunnya imunitas sehingga semakin memperberat gangguan kesehatan. Peran posyandu lansia sangat diperlukan sebagai peran social untuk meningkatkan derajat kesehatan lansia. Tujuan pengabdian masyarakat ini adalah untuk meningkatkan pengetahuan dan ketrampilan kader kesehatan di desa Linggasari, Kembaran, Banyumas dalam upaya meningkatkan derajat kesehatan lansia. Metode pelaksanaan kegiatan dengan cara pendidikan kesehatan, pelatihan, pemberian bantuan paket alat deteksi tekanan darah dan pendampingan. Tahapan yang dilakukan dalam kegiatan ini adalah melakukan diskusi dan studi kasus untuk mengenali gangguan kesehatan yang sering pada lansia, tanda dan gejala, menyusun menu makanan sehat dengan food model dan alih teknologi praktik pengukuran tekanan darah dengan alat digital serta pendampingan. Hasil yang diperoleh menunjukkan bahwa kader mampu mengenali tanda dan gejala beberapa gangguan kesehatan yang sering muncul pada lansia, menyusun menu makanan sehat dan dapat melakukan pemeriksaan tekanan darah secara benar. Penguatan kader kesehatan dalam mengenali gangguan kesehatan pada lansia dapat dilakukan dengan model diskusi studi kasus dan praktik pengukuran tekanan darah.
Spiritual Emotional Freedom Technique (SEFT) untuk Menurunkan Tingkat Kecemasan pada Pasien Hipertensi
Authors: Anam Akhyarul , Upoyo Arif Setyo , Isworo Atyanti , Taufik Agis , Sari Yunita
Published: August 2024

Abstract
Hypertension is a state of increased blood pressure of more than 140/90 mmHg. Hypertension can be caused by individual anxiety and stress factors, and the state of hypertension can trigger anxiety in patients. Efforts that can be made to prevent and overcome anxiety in hypertension can be achieved with independent treatments or interventions such as Spiritual Emotional Freedom Tehnique (SEFT) spiritual therapy that is effective in maintaining blood pressure stability in the normal range. The purposed of this study was to determine of effectiveness health cadres and hypertension sufferers will increase their knowledge and skills on how to reduce anxiety through SEFT therapy. This program was carried out through health education through information transfer, discussion, demonstration, and ongoing assistance to cadres. Participants in this activity were 36 elderly Posyandu health cadres in Mersi Sub-District, Purwokerto Timur District.
Knowledge scores were measured before and after education. The mean value of the pre test was known to be 52.78 while the mean value of the post test was 83.33. The results of paired t test analysis revealed that the value of p = 0,000 showed that there were significant differences between the scores of health cadres' knowledge scores on the understanding of SEFT therapy to reduce anxiety in patients with hypertension between before and after education. SEFT complementary therapy training can effectively improve the knowledge and skills of health cadres and hypertension sufferers in reducing anxiety.
Peningkatan Pengetahuan Dan Keterampilan Kelompok Pedagang Tentang Evakuasi Korban Tenggelam di Belitung
Authors: Sukarna Raden Ade , Amiruddin Amiruddin , Ginanjar Sammy Lazuardi
Published: August 2024

Abstract
 
The increase in tourist visits to aquatic attractions will increase the risk of drowning. For traders in water tourism areas who have the ability to evacuate drowning victims. This activity aims to see if there is an increase in knowledge and skills of traders in the Tanjung Kelayang Beach tourist area after participating in the drowning evacuation training. This community service methods that use training and pre-experiment with the One Group Pretest-Posttest design with participants expected to be 30 traders on Tanjung Kelayang Beach. The activity was carried out in October 2020 and analyzed with a dependent t-test. The results of the evaluation of the activities showed an increase in knowledge (28%) and skills (40%) from before and after attending the training. Statistically there was a significant difference in the mean scores of the pre-test and post-test participants (p <0.005). The conclusion of this activity, effective training can increase the knowledge and skills of participants. Further recommendations need to be formed a special team that has a special post on the island as a tourist destination, because the merchant group is only on the beach.
 
Keywords: training, drowning evacuation, knowledge, skills
Pemberdayaan Karang Taruna dalam Mendukung Gerakan 3M Selama Pandemi Covid-19
Authors: Zaini Mad , Supriyadi Supriyadi , Pratama Koernia Nanda
Published: August 2024

Sasaran program pengabdian masyarakat ini adalah kelompok karang taruna di Kelurahan Kranjingan, Kabupaten Jember. Tujuan dari program ini adalah menambah pemahaman mengenai virus covid-19 serta upaya untuk meningkatkan peran aktif dari karang taruna. Permasalahan yang dihadapi oleh mitra adalah 1) rendahnya peran serta anggota karang taruna dalam pencegahan covid-19, 2) kurangnya kepatuhan masyarakat dalam menjalankan protokol kesehatan, 3) belum ada informasi yang diberikan kepada karang taruna dalam  pencegahan covid-19. Target dan luaran yang dihasilkan adalah 1) produk jasa berupa pengetahuan dan ketrampilan pencegahan covid-19, 2) tersedia buku sederhana pencegahan covid-19, 3) demonstrasi 3M. Metode yang digunakan untuk mencapai tujuan tersebut adalah 1) sosialisasi, 2) pendampingan, 3) demonstrasi gerakan 3M. Hasil dari kegiatan sosialisasi kepada mitra adalah kesepakatan untuk dilakukan penyuluhan dan praktik gerakan 3M pada karang taruna. Kegiatan pengbdian masyarakat ini diikuti oleh 20 karang taruna, dilakukan dengan memberikan pengetahuan dan ketrampilan tentang gerakan 3M kepada karang taruna sebagai upaya bersama dalam membantu masyarakat dalam menanggulangi penyebaran covid-19 khususnya di Kelurahan Kranjingan Kabupaten Jember.
Peer Group Education untuk Pencegahan Stroke Pada Kelompok Hipertensi di Desa Susukan Kecamatan Sumbang Kabupaten Banyumas
Authors: Setyo Arif , Sari Yunita , Ekowati Wahyu
Published: August 2024

The prevalence of hypertension in Indonesia is increasing every year. Based on the Basic Health Research (Riskesdas) in 2013 the prevalence of hypertension was 25.8%, while in the 2018 Riskesdas it increased to 34.1%. The results of the study stated that the prevalence of uncontrolled hypertension in Indonesia was high, which was more than 91%. Uncontrolled hypertension can cause stroke. The prevalence of stroke in Indonesia increases every year, based on Riskesdas in 2013 the prevalence of stroke was 7%0, while at Riskesdas in 2018 the prevalence of stroke was 10.9%0. The results of the survey of the hypertension group in Susukan Village, Sumbang Subdistrict showed that the majority of hypertension sufferers had low education (91.67%), low knowledge of hypertension (45.83%), uncontrolled blood pressure >140mmHg (83.33%), stroke prevention behavior was low (54.17%). Implementation methods include training on the introduction of hypertension, stroke risk and the benefits of Peer Group Education for stroke prevention, training on prevention of stroke in the hypertension group through a healthy lifestyle (diet, physical activity and stress management), training in early detection of stroke, training in blood pressure monitoring and style monitoring. life of hypertensive patients to prevent stroke. The results showed 90% of participants increased knowledge about hypertension as measured by HKLS, 90% of participants were able to explain a healthy diet in hypertension for stroke prevention, 100% of participants were able to explain physical activity or exercise in hypertension sufferers, 100% of participants were able to explain psychological stress management in hypertension. , 100% of the group were able to demonstrate blood pressure measurement, 100% of the group were able to fill out a healthy lifestyle monitoring sheet for patients with hypertension, 100% of the group were able to demonstrate early detection of stroke. Conclusion: Training increases the knowledge and skills of partners in stroke prevention effectively.
PELATIHAN CALON KADER POSYANDU REMAJA DI DESA KARANGSALAM KIDUL KEDUNGBANTENG BANYUMAS
Authors: Sari Hesti Permata , Sulistyaning Afina Rachma , Farida Farida
Published: August 2024

Adolescence is the second period of growth and development after toddlerhood. Teenagers are faced with nutritional problems that prevent them from optimally reaching their potential. Prevention can be done by early detection of nutritional problems by peers through Youth Posyandu. This activity aims to increase knowledge and attitudes related to nutrition and skills in measuring nutritional status in prospective Youth Posyandu cadres in Karangsalam Kidul, Kedungbanteng, Banyumas using nutrition education methods and training in measuring nutritional status. Data analysis used the dependent t-test. The result is an increase in the knowledge, attitudes, and skills of prospective Youth Posyandu cadres. This education and training are expected to create Youth Posyandu cadres who care about adolescent nutrition.
Edukasi PHBS melalui Pemberdayaan Santri di Pondok Pesantren Modern Daarul Abror Bangka
Authors: Chaerani Erni , Widyaastuti Eny Erlinda , Djuria Syafrina Arba'ani
Published: August 2024

Pembangunan kesehatan merupakan upaya yang dilaksanakan dengan tujuan untuk meningkatkan kesadaran, kemauan, dan kemampuan hidup sehat bagi setiap orang  termasuk  santri pondok pesantren agar terwujud derajat kesehatan yang setinggi tingginya. Perilaku hidup bersih dan sehat (PHBS) merupakan salah satu cara mencapai derajat kesehatan yang baik. Pondok Pesantren Modern Daarul Abror  merupakan  pesantren di Bangka Belitung yang terletak di Kecamatan Mendo Barat Kabupaten Bangka. Pengasuh dan pengurus pesantren telah berupaya menyediakan sarana dan memberikan pengetahuan pentingnya PHBS, tetapi para santri masih mengalami kesulitan dalam mengimplemetasikan nilai-nilai kesehatan karena kurangnya pengetahuan tentang dasar-dasar kesehatan dan PHBS sehingga kesadaran akan berperilaku hidup bersih dan sehat belum optimal. Edukasi PHBS dengan memberdayakan santri sebagai kader kesehatan merupakan kegiatan pengabdian kepada masyarakat (PkM) yang berupaya membelajarkan santri menjadi pemimpin dan role model dalam berperilaku hidup bersih dan sehat. Metode yang digunakan dalam PkM adalah metode partisipatoris. Metode dimaksud  tim pengabdi  turun langsung melakukan edukasi PHBS kepada kader kesehatan santri dalam bentuk pelatihan. Santri yang dilatih menjadi kader berjumlah 27 orang. Pengetahuan kader santri meningkat setelah diberi pelatihan,  rata-rata nilai pre test 74.63 dan  post test 83.33. Santri mendapat pengalaman menjadi fasilitator dalam memonitor pelaksanaan PHBS di pesantren. Solusi permasalahan PHBS di Pondok Pesantren Daarul Abror tidak lepas dari peran  pimpinan dan pembina santri.   Keberhasilan santri menjadi kader kesehatan karena dukungan pembina pesantren yang kooperatif    mendampingi santri dalam menjalankan perannya sebagai kader kesehatan. Memberdayakan santri  menjadi kader kesehatan dapat mempercepat tercipta pesantren yang sehat.
LASSO–MOGAT: a multi-omics graph attention framework for cancer classification
Authors: Alharbi Fadi , Vakanski Aleksandar , Elbashir Murtada K. , Mohammed Mohanad
Published: August 2024

The application of machine learning (ML) methods to analyze changes in gene expression patterns has recently emerged as a powerful approach in cancer research, enhancing our understanding of the molecular mechanisms underpinning cancer development and progression. Combining gene expression data with other types of omics data has been reported by numerous works to improve cancer classification outcomes. Despite these advances, effectively integrating high-dimensional multi-omics data and capturing the complex relationships across different biological layers remain challenging. This article introduces Least Absolute Shrinkage and Selection Operator–Multi-omics Gated Attention (LASSO–MOGAT), a novel graph-based deep learning framework that integrates messenger RNA, microRNA, and DNA methylation data to classify 31 cancer types. By utilizing differential expression analysis (DEG) with Linear Models for Microarray (LIMMA) and LASSO regression for feature selection and leveraging graph attention networks (GATs) to incorporate protein–protein interaction (PPI) networks, LASSO–MOGAT effectively captures intricate relationships within multi-omics data. Experimental validation using fivefold cross-validation demonstrates the method’s precision, reliability, and capacity to provide comprehensive insights into cancer molecular mechanisms. The computation of attention coefficients for the edges in the graph, facilitated by the proposed graph attention architecture based on PPIs, proved beneficial for identifying synergies in multi-omics data for cancer classification.
A trial helicopter survey of crane nesting on floodplains in the Gulf Plains Bioregion, north-western Queensland, and the first record of a three-egg clutch for the Australian Sarus Crane Grus antigone gillae
Authors:   Cairns Institute, James Cook University, P.O. Box 6811, Cairns QLD 4870, Australia, Nevard Timothy , Scrambler Elinor ,   International Crane Foundation, E11376 Shady Lane Road, Baraboo WI 53913, United States of America,   P.O. Box 1383, Atherton QLD 4883, Australia, Archibald George ,   International Crane Foundation, E11376 Shady Lane Road, Baraboo WI 53913, United States of America
Published: August 2024

Nesting ecology of the Australian Sarus Crane Grus antigone gillae is the least well known of the four global Sarus Crane populations. All confirmed breeding sites are in Queensland, concentrated on seasonally flooded wetlands in the Gulf Plains bioregion, where the Australian Sarus Crane is sympatric with the Brolga G. rubicunda. This article describes a trial helicopter survey of crane nesting in February 2017, carried out under the auspices of the International Crane Foundation and with the participation of the Normanton Land and Sea Rangers. We report the first record of a three-egg clutch for the Australian Sarus Crane. All Australian Sarus Crane nests were found in habitats with trees, whereas only Brolgas were found nesting in treeless tussock grassland and in saline habitats. Since the last nest survey in 1984, numbers of Estuarine Crocodiles Crocodylus porosus have grown to the point where foot surveys are no longer safe, and this study shows that helicopters could provide a useful alternative method for further surveys of crane nests in the Gulf Plains bioregion.
Treating Anxiety-Based Cognitive Distortions Pertaining to Somatic Perception for Better Chronic Pain Outcomes
Authors: Silva Marcelina Jasmine
Published: August 2024

Anxiety-based cognitive distortions pertaining to somatic perception (ABCD-SP) - primarily catastrophizing, fear avoidance and kinesiophobia- have been repeatedly linked to worsening chronic, non-cancer pain (CNCP) outcomes of increased disability, amplified pain, ineffective opioid use, and opioid misuse. Several studies have suggested that treating ABCD-SP can improve pain outcomes. Utilizing a narrative review of proposed mechanisms, published patient perspectives, and study correlates connecting these cognitive distortions with CNCP outcomes, a better practice approach to the delivery of standard clinical CNCP care can be deduced. These recommendations require relatively few resources to implement and have the potential to lead to more effective CNCP treatment on a large scale.
The Interlinking Metabolic Association between Type 2 Diabetes and Cancer: Molecular Mechanisms and Therapeutic Insights
Authors: Asiri Abutaleb , Al Qarni Ali Ahmed , Bakillah Ahmed
Published: August 2024

Type 2 Diabetes mellitus (T2DM) and cancer share common risk factors including obesity, in-flammation, hyperglycemia, and hyperinsulinemia. High insulin levels activate PI3K/Akt/mTOR signaling pathway promoting cancer cell growth, survival, proliferation, metastasis, and an-ti-apoptosis. The inhibition of PI3K/Akt/mTOR signaling pathway for cancer remains a promising therapy, however, the combination of therapeutic inhibitors may solve the resistance to such agents. Understanding the metabolic link between diabetes and cancer can assist in improving the therapeutic strategies used for the management of cancer patients with diabetes and vice versa. This review provides an overview of shared molecular mechanisms between diabetes and cancer as well as discusses established and emerging therapeutic anti-cancer agents targeting the PI3K/Akt/mTOR pathway in cancer management.
Glutamate Transporter 1 as a Novel Negative Regulator of Amyloid β
Authors: Sinha Priyanka , Turchyna Yuliia , Mitchell Shane , Sadek Michael , Armagan Gokce , Perrin Florian , Maesako Masato , Berezovska Oksana
Published: August 2024

Glutamate transporter-1 (GLT-1) dynamics are implicated in excitotoxicity and Alzheimer's disease (AD) progression. Early stages of AD are often marked by hyperactivity and increased epileptiform activity preceding cognitive decline. Previously, we identified a direct interaction between GLT-1 and Presenilin 1 (PS1) in the brain, highlighting GLT-1 as a promising target in AD research. This study reports the significance of this interaction and uncovers a novel role of GLT-1 in modulating amyloid-beta (Aβ) production. Overexpression of GLT-1 in cells reduces the levels of Aβ40 and Aβ42 by decreasing γ-secretase activity pertinent to APP processing and induces a more "open" PS1 conformation, resulting in decreased Aβ42/40 ratio. Inhibition of the GLT-1/PS1 interaction using cell-permeable peptides produced an opposing effect on Aβ, highlighting the pivotal role of this interaction in regulating Aβ levels. These findings emphasize the potential of targeting GLT-1/PS1 interaction as a novel therapeutic strategy for AD.
Bacterial and Viral Co-Infections in COVID-19 Patients: Etiology and Clinical Impact
Authors: Madzharova Iveta Rumenova , Trifonova Ivelina , Korsun Neli Stoyanova , Levterova Viktoria , Velikov Petar , Voleva Silvya , Ivanov Ivan , Ivanov Daniel , Yordanova Ralitsa , Tcherveniakova Tatiana , Angelova Svetla , Christova Iva
Published: August 2024

The risk of a fatal outcome was 41% in unvaccinated patients (p = 0.713), which increased by 2.66% with co-infection with two pathogens (p = 0.342) and by 26% with three pathogens (p = 0.005). Additionally, 50% of ICU patients had a triple infection, compared with only 1.3% in the inpatient unit (p = 0.0029). The risk of death and/or ICU admission was 12 times higher (p = 0.042) with an additional pathogen and increased by 95% (p = 0.003) with a third concomitant pathogen. Regular multiplex testing is important for prompt treatment and targeted antibiotic use.
A Step Forward in Enhancing the Health-Promoting Properties of Whole Tomatoes as a Global Functional Food to Lower the Impact of Non-Communicable Diseases
Authors: Natali Pier Giorgio , Piantelli Mauro , Sottini Alessandra , Eufemi Margherita , Banfi Cristina , Imberti Luisa
Published: August 2024

Nutritional interventions facilitating the consumption of available, affordable, and environment-compatible health-promoting functional foods (FF) are a promising strategy for controlling non-communicable diseases (NCDs) responsible for decreasing health expectancy. Given that the complex of tomato micronutrients produces healthier outcomes than lycopene, its major antioxidant component, we have devised a new controlled berry processing to improve its health-supporting properties. The newly generated whole tomato food supplement (WTFS), enriched by 2% olive wastewater polyphenols, contains a complex of healthy nutrients with converging biologic activities superior to those provided by tomato commodities. WTFS equals the antioxidant activity of N-acetyl-cysteine and interferes with multiple inflammation-eliciting and sustaining metabolic pathways. WTFS inhibits prostate experimental tumors, and improves benign prostate hypertrophy-associated symptoms. No side effects have been so far reported for dietary supplementation with WTFS compared to the culinary use of tomatoes. Although WTFS may be susceptible to further improvements and clinical scrutiny, its composition embodies the features of an advanced FF to ease adherence to dietary regimens, i.e. the Mediterranean diet, aimed at contrasting the low-grade inflammation. Ongoing investigations suggest new areas of potential translational use of WTFS, as a basis for developing more targeted FF interceptive or preventive of NCDs.
Open-Source Indoor Horizontal Grow Structure Designs
Authors: Qian Jun-yu , Pearce Joshua M.
Published: August 2024

Agrivoltaic agrotunnels are currently designed for high density grow walls that are not amenable to bush berries or root crops. Commercial grow bins provide deeper substrates for produce with more root systems but have high costs per unit growing area. To overcome the economic limitations of grow bins, this study applies the distributed manufacturing open-source design paradigm to develop four designs for low-cost open source structures. The designs target root vegetables and bush fruit specifically to be adopted by remote communities with limited or no outdoor growing environment to offset the market price for imported fresh produce. The indoor growing designs provide the necessary structure for supporting grow light and grow bins and enabled the transplanted berry plants to flower and produced fruits. They provide a comparable amount (110L) or more of grow volume from 106 to 192 L. The water reservoir volume for the commercial system (62 L) and grow area (0.5 m³) is surpassed by all new designs that range from 64 to 192 L and 0.51 to 0.76 m³, respectively. These superior properties are possible with material costs for all four designs that save more than 90% of the economic cost of the commercial systems.
Application of Pyroligneous Acid as a Plant Growth Stimulant can Improve the Nutritional Value of Soybean Seed
Authors: Noel Randi , Schueller Michael J. , Guthrie James , Ferrieri Richard A
Published: August 2024

Farmers today are using biochemical treatments to improve their crop yields. Commercialized organic biostimulants exist in the form of pyroligneous acid generated by burning agricultural waste products. During the 2023 growing season we demonstrated that soil treatment with a commercial pyroligneous acid product, Coriphol™, manufactured by Corigin Solutions, Inc., stimulated plant growth and significantly improved yield with an optimal treatment dose of 2 gal./acre. In the present work we examined the effect of this treatment on soybean nutritional content using seed harvested from the 2023 season. Total mean seed protein content for untreated control plants was 32.26 ± 0.49% of dry mass and increased 10.8% to 35.64 ± 0.64% with treatment. This increase resulted in a net reduction in total free amino acid content although levels of the es-sential dietary amino acid, lysine, were boosted 6-fold. Total lipid content was unaffected by treatment with mean levels of 21.61 ± 0.70% of dry mass noted. Treatment, however, reduced saturated fatty acid content by roughly 40% while reducing the polyunsaturated content of linoleic acid in favor of the monounsaturated fatty acid, oleic acid. Finally, Coriphol™ treatment did not impact seed content of eight essential micronutrients including Na, Mg, K, Ca, Fe, Ni, Cu and Mo, but did significantly boost Zn and Mn levels. Altogether, these results demonstrate that soil treat-ment with the growth stimulant Coriphol™ has the potential to improve the dietary nutritional value of soybean.
A Strategy of Weak-Connected Grid Search for Noise Filtering and Density Grid-Based Data Clustering
Authors: Truong Nang Toan , Nguyen Sy Dzung , Choi Seung-Bok
Published: August 2024

One of the efficient data mining tools is density-based clustering, including the density grid-based clustering. However, a common drawback always existing in clusters made by the density grid-based method is the existence of weakly connected grids deriving mainly from noise. Appearing such an unwanted connection with a high frequency reduces the accuracy of the obtained cluster data space (CDS) and its application efficiency. Here, we present an essential improvement to overcome this problem. First, we describe a concept of the weak-connected grid cell (WCG) and present a fuzzy-type approximation to depict the density-based distribution of data points at grid nodes. Then, we propose a strategy of searching WCG for density grid-based clustering (SWCG-DGB) to set up a CDS, filter noise, and tune the created CDS. A buffer is deployed during this phase to collect border points and filter noise, which improves the computational time significantly, especially for noisy datasets. Results from numerical surveys reflected the compared efficiency of this method in clustering validity, including the accuracy of the number of clusters.
Imaging the Raf–MEK–ERK Signaling Cascade in Living Cells
Authors: Shin Young-Chul , Cho Minkyung , Hwang Jung Me , Myung Kyungjae , Kweon Hee-Seok , Seong Hyun-A , Lee Zee-Won , Lee Kyung-Bok
Published: August 2024

Conventional biochemical methods for studying cellular signaling cascades have relied on destructive cell disruption. In contrast, live cell imaging of fluorescent-tagged transfected proteins offers a non-invasive approach to understanding signal transduction events. One strategy involves monitoring the phosphorylation-dependent shuttling of a fluorescent-labeled kinase between the nucleus and cytoplasm using nuclear localization, export signals, or both. This paper introduces a simple method to visualize intracellular signal transduction in live cells by exploring the translocation properties of PKC from the cytoplasm to the membrane. We fused bait protein to PKC, allowing the bait (RFP-labeled) and target (GFP-labeled) proteins to co-translocate from the cytoplasm to the membrane. However, in non-interacting protein pairs, only the bait protein was translocated to the plasma membrane. To verify our approach, we examined the Raf–MEK–ERK signaling cascade (ERK pathway) and directly observed the Raf1/MEK2 interaction. We also identified ternary complexes containing the KSR1 scaffold protein. Additionally, the MEK/ERK interaction was dependent on the exogenous expression of KSR1.
Enhancing Multilingual Table-to-Text Generation with QA Blueprints: Overcoming Challenges in Low-Resource Languages
Authors: Soni Arpita
Published: August 2024

Limiting training data in low-resource languages is a barrier to Natural Language Processing (NLP). Regardless, languages with thousands of users worldwide require improved NLP capabilities. The Table-to-Text task—typically develops natural language descriptions using data tables, tests model reasoning abilities—although it is especially tough in multi-language settings. System output frequently lack credit to their underlying data. Intermediate planning strategies—which include Question-Answer (QA) blueprints—improving summarization tasks by presenting related QA pair prior to verbalization. Therefore, this study analyses whether QA blueprints improve multilingual Table-to-Text output attribution. An enlarged multilingual dataset, encompassing African languages, contains QA blueprints that were produced and filtered heuristically. This dataset is used to fine-tune sequence-to-sequence model (transformers)—both with and without blueprints. Two configurations are evaluated—English reference blueprints with language target verbalization and modified blueprints. These results show that English-only models benefit from blueprints, whereas multi language models cannot. Errors in machine-translating blueprints provide challenges, as do models that rely on their generated blueprints.
The Role of Bioelectrical Patterns in Regulative Morphogenesis: An Evolutionary Simulation and Validation in Planarian Regeneration
Authors: Hansali Sammy , Pio-Lopez Léo , LaPalme Jennifer V. , Levin Michael
Published: August 2024

Endogenous bioelectrical patterns are an important regulator of anatomical pattern during embryogenesis, regeneration, and cancer. While there are three known classes of instructive bioelectric patterns: directly encoding, indirectly encoding, and binary trigger, it is not known how these design principles could be exploited by evolution and what their relative advantages might be. To better understand the evolutionary role of bioelectricity in anatomical homeostasis, we developed a neural cellular automaton (NCA). We used evolutionary algorithms to optimize these models to achieve reliable morphogenetic patterns driven by the different ways in which tissues can interpret their bioelectrical pattern for downstream anatomical outcomes. We found that: (1) All three types of bioelectrical codes allow the reaching of target morphologies; (2) Resetting of the bioelectrical pattern and the change in duration of the binary trigger alter morphogenesis; (3) Direct pattern organisms show an emergent robustness to changes in initial anatomical configurations; (4) Indirect pattern organisms show an emergent robustness to bioelectrical perturbation; (5) Direct and indirect pattern organisms show an emergent generalizability competency to new (rotated) bioelectrical patterns; (6) Direct pattern organisms show an emergent repatterning competency in post-developmental-phase. Because our simulation was fundamentally a homeostatic system seeking to achieve specific goals in anatomical state space, we sought to understand the role of anxiolytics that reduced concern over the distance to those goals. We simulated selective serotonin reuptake inhibitors, which diminished ability of artificial embryos to correctly interpret bioelectric patterns due to an altered organismal reward machinery, leading to higher variance of developmental outcomes, global morphological degradation, and induced in some organisms anatomical bistability. These computational findings were validated by data collected from in vivo experiments in SSRI exposure in planarian flatworm regeneration.
Evaluation of Solid Phase Joining Using Friction Stir Welding Technique between Aluminum 6061 and
Polymer-Based Composites
Authors: ALI NOUMAN , Abadeen Zain ul , Qureshi Yumna
Published: August 2024

Solid-phase joining is a technique used to fuse two materials by applying heat and pressure, causing plastic deformation without reaching the melting point. This method is applicable for similar and dissimilar materials, including metals, polymers, and ceramics, without the need for filler material. Among the various methods, Friction Stir Welding (FSW) is preferred for joining dissimilar materials due to its solid-state process, which enhances mechanical properties, metallurgical compatibility, and reduces distortion. FSW is particularly effective for materials with significant differences in melting points. The current project focuses on assessing the strength and mechanical properties of FSW joints between aluminum and polymer-based composites. FSW was selected for its ability to produce fine-grained, strong welds free from fusion-related defects such as porosity and cracks. Applications in sectors like automotive, aerospace, and shipbuilding are explored, with impact, hardness, and tensile tests conducted to evaluate joint performance. This comprehensive study includes literature review, fabrication, testing, and tool design to ensure a thorough understanding of dissimilar joint properties.