bluuebunny/crossref_metadata_2025 huggingface dataset:
Risk factors, incidence and clinical aspects of sporotrichosis in dogs and cats in Campos dos Goytacazes, RJ
Authors: Félix Aline de Oliveira , Pereira Gabriela Martins , Almeida Adriana Jardim de , Araújo Lorena Costa , Araujo Giulia Del Giudice Figueiredo de , Vieira-da-Motta Olney
Published: May 2022

The sporotrichosis is an endemic disease with cosmopolitan distribution, caused by the fungi Sporothrix schenckiicomplex, which affects animals and humans. In Brazil, sporotrichosis is an emerging zoonosis, recently included in the National List of Compulsory Notification of diseases, injuries and events in public health issued by the Ministry of Health. The present study aimed to analyze clinical and epidemiological aspects of sporotrichosis in cats and dogs in the municipality of Campos dos Goytacazes, RJ. For this study, 805 animal patients with suspected lesions of sporotrichosis were included, i.e., 749 cats and 56 dogs, and they were attended at the Veterinary Hospital/Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF). The results showed that 76.37% of the cats were positive for sporotrichosis, with a higher proportion of males. Regarding the dogs, 41.07% were positive for the disease, and among these animals, 45.45% of the females and 34.78% of the males were positive for sporotrichosis. It was observed that 77.40% of the cats could roam freely in the peridomestic area and 72.20% were not neutered. The results showed that both cats and dogs that were not neutered and could roam freely in the peridomestic area were more susceptible to be affected by sporotrichosis.
Electrocardiographic findings in dogs with obstructive airway diseases
Authors: Silva Jaíne da , Gonçalves Bruna Pereira , Machado Eduarda de Oliveira Silva Lima , Paiva Bianca Affonso dos Santos , Carvalho Eduardo Butturini de , Santos Filho Mário dos
Published: May 2022

Cardiac rhythm disorders are diagnosed through electrocardiography, which is an important tool to investigate other systemic conditions that may be related to the cardiac conduction system. Cardiac regulation is controlled by the autonomic nervous system, and in dogs, it is mainly modulated by a parasympathetic action exerted by the vagus nerve, called vagal tone. Increased vagal tone can occur physiologically or pathologically, leading to the occurrence of bradyarrhythmias. However, some studies report that airway diseases can exacerbate this tone, together with the reduction of sympathetic pathway activities. This study aimed to analyze the cardiac rhythms in dogs presenting with electrocardiographic alterations related to respiratory diseases, in connection with the exacerbation of vagal tone. Medical records of animals whose diagnoses involved at least one respiratory condition and who underwent electrocardiographic assessment between March 2017 to March 2021 were compiled. Data obtained were compiled in Microsoft Excel®1 spreadsheets and evaluated using descriptive statistics through the BioEstat®2 software. Pearson’s correlation was used for quantitative data. A correlation between autonomic regulation and vagal exacerbation was observed in cases with obstructive airways diseases.
Neurological Complications in Systemic Inflammatory Diseases
Authors: Casanova Ignacio , Prada Alejandro , De Silanes Carlos López , Gonzaga Luis , Barrio Laura , Eimil Miriam , Oyanguren Beatriz , Alcántara Pilar , Saíz Miguel Ángel , Díaz Blanca , González Miriam , González Marta
Published: May 2022

Systemic inflammatory diseases could produce neurologic complications, and they are
frequently incorporated in the differential diagnosis of neurological symptoms. There are wellestablished
criteria to meet the diagnosis of neurologic manifestations of these systemic diseases.

Methods:

However, the range of clinical presentations varies in each condition, and the prevalence
of these complications differs between studies. Hence, in many cases, an etiological relationship is
not clearly defined.

Results and Conclusion:

For these reasons, it is challenging to make an accurate diagnosis. We analyzed
the spectrum of neurological manifestations in a cohort of patients with systemic lupus erythematosus,
rheumatoid arthritis, Behçet disease and sarcoidosis in order to improve our current
knowledge of these complications.
Cerebral Vasoreactivity in a Fabry Disease Patient
Authors: Siniscalchi Antonio , La Russa Antonella , Lochner Piergiorgio , Petrone Alfredo , Russo Bina
Published: May 2022

Background:

Fabry disease (FD) is a rare X-linked multisystem lysosomal storage disease
caused by partial or total deficiency of a-galactosidase A (GLA). A progressive involvement of the
kidneys, heart, and brain arteries has been reported. Using the transcranial color-coded duplex Doppler
(TCCD), we report the case of a Fabry disease (FD) patient with a reduction in the cerebrovascular
reactivity of the basilar artery (BA).

Methods:

A 46-year-old male asymptomatic FD patient underwent ultrasound intracranial investigation.

Case Report:

We report the case of a 46-year-old man affected by asymptomatic FD, who
presented to our observation for episodes of vertigo. Cerebral MRI and AngioMRI were found to be
normal. There was no postural hypotension observed. Otolaryngology and cardiac examinations revealed
no pathological condition. A TCCD showed normal cerebral vascular reactivity (CVR) in the
bilateral middle cerebral arteries (MCA), breath-holding index (BHI) was 1.3 in the right MCA (RMCA)
and 1.4 in left MCA (LMCA), and BHI in the basilar artery (BA) was reduced (BHI: 0,56).

Conclusion:

This case suggests an earlier alteration of CVR in the posterior cerebral circulation than
in the anterior cerebral circulation in an asymptomatic FD patient. This alteration of CVR may be an
earlier marker of FD diagnosis.
Celastrol Loaded PEGylated Nanographene Oxide for Highly Efficient Synergistic
Chemo/Photothermal Therapy
Authors: Liang Jianying , Song Xiaoxia , Zhu Rongrong , Guo Dandan , Dai Wei
Published: May 2022

Aim:

The main aim of this study is to improve the solubility, reduce side effects and increase the therapeutic
efficacy of CSL by using functionalized graphene oxide as a carrier, to fulfill chemo-photothermal therapy.

Background:

Celastrol (CSL), which is extracted from the traditional Chinese medicinal plant Tripterygium wilfordii,
has reported significant antitumor activity in vitro and in vivo cancer models. However, disadvantages with regard to
solubility, short plasma half-life and toxicity hinder its use in pharmaceutical application. Nanocarrier delivery system
could be employed to improve the biochemical and pharmacokinetic performance of CSL. Among numerous nanocarriers,
graphene oxide is one of the most promising nanocarriers due to its intrinsic physical and chemical properties and
good biocompatibility.

Objective:

Here, we employed a PEGylated reduced nanographene oxide CSL complex (nrGO-PEG/CSL) as a new
drug delivery system to achieve highly efficient synergistic chemo/photothermal therapy.

Methods:

A functionalized nrGO-PEG was synthesized and the loading capacity of CSL, photothermal effect and
release efficiency under different pH and NIR irradiation were measured in the first stage of work. In vitro and in vivo
anticancer effects of prepared nrGO-PEG/CSL complex were evaluated on 4T1 cells and 4T1 tumor-bearing mice,
respectively, with the association of NIR laser irradiation.

Results:

The functionalized nrGO-PEG exhibited excellent drug loading capacity of CSL (20.76 mg/mg GO) and
photothermal effect (~3.0 -fold increment over unreduced nGO-PEG). Loaded CSL could be efficiently released from
nrGO-PEG/CSL complex by NIR irradiation in vitro. In vivo study performed on 4T1 tumor-bearing mice proved that
nrGO-PEG/CSL with NIR laser irradiation shows superior anticancer effects.

Conclusion:

The experimental data demonstrated that the nrGO-PEG/CSL-mediated chemo/photothermal combination
therapy was more cytotoxic to cancer cells than only chemotherapy or photothermal treatment, reducing the occurrence
of tumor metastasis. Therefore, nrGO-PEG/CSL-mediated chemo/photothermal is expected to be a promising treatment
for synergistic cancer therapy.
A Generalized Review Of Human-Computer Interaction Using Electromyogram
Signals
Authors: Maity Sourav , Veer Karan
Published: May 2022

The primary use of human computer interaction is in smart home as well as in industry 4.0. Communication between computer and human can be benefitted by a spontaneous interchange of emotions. The objective of the work is to provide an idea regarding the process of identifying various emotions using facial electromyography signals through electrode placement method. Here one contemplated the facial electromyography on masticatory function assessment and emotional articulation monitoring. Furthermore, we have also presented the measurement of facial electromyography including selection of electrode, location of electrode and reduction of noise. Facial emotions have significant effect on cognitive process of the human brain such as doubt perception, ability to solve problems, learning capabilities, emotional interactions and memory which is beneficial while interacting with patients suffering from depression and stress. The patients are guided through their rehabilitation process by rehabilitation application while accustoming itself to patient’s emotional state or wellbeing, which results in high motivation as well as in a quicker. This review paper will motivate and inspire researchers and engineers for finding more suitable system for various applications.
An Infrared and Visible Image Fusion Approach of Self-calibrated
Residual Networks and Feature Embedding
Authors: Dai Jinpeng , Luo Zhongqiang , Li Chengjie
Published: May 2022

Background:

The fusion of infrared image and visible image has been a hot topic in the field of image fusion. In the process of image fusion, different methods of feature extraction and processing will directly affect the fusion performance.

Objectives:

Low resolution (small size) of high-level features will lead to the loss of spatial information. On the other side, the low-level features are not significant due to their insufficient filtering of background and noise.

Methods:

In order to solve the problem of insufficient feature utilization in existing methods, a new fusion approach (SC-Fuse) based on self-calibrated residual networks (SCNet) and feature embedding is proposed. The method improves the quality of image fusion from two aspects: feature extraction and feature processing.

Results:

First, self-calibrated modules are applied to the field of image fusion for the first time, which enlarged the receptive field to make feature maps contain more information. Second, we use ZCA (zero-phase component analysis) and l1-norm to process features, and propose a feature embedding operation to realize the complementarity of feature information at different levels.

Conclusion:

Finally, a suitable strategy is given to reconstruct the fused image. After ablation experiments and comparison with other representative algorithms, the results show the effectiveness and superiority of SC-Fuse.
Additive manufacturing of capacitive humidity sensors by screen printing for condition monitoring of FRP composites
Authors: Seifert Tobias , Martin Jörg , Seider Thomas , Wiemer Maik , Otto Thomas
Published: May 2022

Screen printing as a method of additive manufacturing applicable for the production of highly sensitive humidity sensors is presented. For this purpose, manufacturing, benchmarking and optimization of sensitive micro-composite dielectric paste systems suitable for screen printing are demonstrated. Furthermore, commercially available silver paste systems were rheologically and electrically characterized and benchmarked. Thereby bulk silver conductivities of up to 15 % were measured with average layer thicknesses in the range between 3 - 10 μm and an occurring surface roughness Ra between 0.7 - 3.7 μm. The printed sensors capacitance was measured along with the characterization of its humidity sensing capability. The capacitance of the printed sensors varied between 6.2 - 8.5 pF depending on the layer thickness of the micro-composite dielectric materials and increased up to 26 pF while detecting 90 % relative humidity. Differences between water molecule absorption and desorption are determined by the occurring hysteresis between the detection of increasing and decreasing humidity. Malfunctions of the sensors due to the arising cross contact between top and bottom electrode could be addressed by varying the layer thickness or selection of materials.
The Effects of Overweight and Obesity on Obstacle Crossing During Walking: Protocol for a Systematic Review
Authors: Chardon Matthias , Barbieri Fabio Augusto , Penedo Tiago , Santos Paulo Cezar Rocha , Vuillerme Nicolas
Published: May 2022

Background

Overweight and obesity are significant global health concerns that involve deficits in gait and balance that affect daily activities. Although much is reported about the effect of overweight and obesity on gait during unobstructed walking, not much is known about how overweight and obesity could impact gait under more challenging conditions, such as environments with obstacles.

Objective

The aim of this study is to systematically review and synthesize the available data regarding the effects of overweight and obesity on obstacle crossing during walking.

Methods

This review will follow the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines. PubMed, Web of Science, Scopus, and SPORTDiscus will be systematically searched with no limitations on publication date. Only full-text English-language articles published in a peer-reviewed journal will be included. Included articles must have compared obstacle crossing during walking in individuals with overweight or obesity to individuals of normal body weight. A total of 2 independent reviewers will select the articles and extract the following 4 sets of data: (1) study characteristics, (2) sample description, (3) obstacle crossing task protocol, and (4) main results obtained. If a considerable number of homogeneous papers are included, a meta-analysis will be conducted. A preliminary search was conducted in November 2021.

Results

The results will include the article selection flowchart as well as tables and figures synthesizing the extracted data on the effects of overweight and obesity on obstacle crossing during walking. The preliminary search identified 73 original records, of which 5 articles met the inclusion criteria.

Conclusions

This review will present researchers and clinicians with an overview of published studies that have compared the performance of obstacle crossing for individuals with overweight and obesity to those of normal body weight. Gaining insight into the control strategies adopted by individuals with overweight and obesity is critical for safe and successful obstacle crossing in this population. We therefore believe that our findings could be useful for identifying people at risk of falls and developing and implementing fall prevention programs for individuals with overweight and obesity.

Trial Registration

PROSPERO CRD42021269949; https://tinyurl.com/3yrwccu4

International Registered Report Identifier (IRRID)

DERR1-10.2196/36234
Does the number of social media platforms used and the time spent on social media impact adolescents’ health-related quality of life (Preprint)
Authors: You Yueyue , Yang-Huang Junwen , Raat Hein , Van Grieken Amy
Published: May 2022

BACKGROUND

Social media use is increasing among children. The impact of social media use on children’s health-related quality of life (HRQoL) remains unclear.

OBJECTIVE

This study assessed the associations between the number of social media platforms used, the time spent on social media and HRQoL among children aged 13 years.

METHODS

Data of 3,397 children from the Generation R Study, a population-based cohort study in the Netherlands, were analyzed. Children reported the number of social media platforms used and the time spent on social media during weekdays and weekends separately. Children’s HRQoL was self-reported with the EQ-5D-Y. Multiple logistic and linear regression models were applied.

RESULTS

In this study, 73% of children used 3 or more social media platforms, and 38% and 58% of children used social media at least 2 hours per day during weekdays and weekends. Children using more social media platforms had a higher odds of reporting having some or a lot of problems on ‘having pain or discomfort’ and ‘feeling worried, sad or unhappy’ dimensions (all p-values < 0.05) and reported lower self-rated health (β =-3.81; 95% CI: -5.54, -2.09). Both on weekdays and weekends, children spent more time on social media were more likely to report having some or a lot of problems on ‘doing usual activities’, ‘having pain or discomfort’, ‘feeling worried, sad or unhappy’, and report lower self-rated health (all p-values < 0.05).

CONCLUSIONS

The findings indicate that using more social media platforms and spending more time on social media were significantly associated with lower HRQoL. We recommend future research to study the pathway between social media use and HRQoL among adolescents.

CLINICALTRIAL

NA
Correction: Access to Electronic Personal Health Records Among Patients With Multiple Chronic Conditions: A Secondary Data Analysis (Preprint)
Authors: Greenberg Alexandra J , Falisi Angela L , Finney Rutten Lila J , Chou Wen-Ying Sylvia , Patel Vaishali , Moser Richard P , Hesse Bradford W
Published: May 2022

UNSTRUCTURED

Correction: Access to Electronic Personal Health Records Among Patients With Multiple Chronic Conditions: A Secondary Data Analysis
Metaphorical Expressions with “Sweet” in English and “Ng?t” in Vietnamese
Authors: Thu Ho Trinh Quynh , Ha Nguyen Thi Thanh
Published: May 2022

On the foundation of Conceptual Metaphor Theory and the 4-step metaphor identification procedure by Pragglejaz Group, the paper discovers 87 metaphorical expressions containing the word “sweet” in English, equivalent to “ng?t” in Vietnamese through an investigation into four English and four Vietnamese novels composed in the 20th century. These gustatory expressions are found to be used to describe other senses, including olfaction, audition, vision, and tactition. Besides, the metaphorical expressions with “sweet” and “ng?t” are also employed to talk about emotion and manner. Despite several resemblances between English and Vietnamese metaphorical expressions containing the words “sweet” and “ng?t”, which are shed light upon by the universality of metaphors and human embodied experience, there are some differences in expressing the world via these two words between the two languages that are assigned to distinctive linguistic characteristics in each language.
Democracy Crisis: Decline of Rule of Law
Authors: Lane Jan-Erik
Published: May 2022

World Justice Project (WJP) measures the respect for rule of law globally. Its 2021 report establishes a decline compared with earlier years. For the US the ranking is really down. What does ìt all mean?
Using the (University Governance Screening Modified Card) to Evaluating the Level of Governance in Iraqi Universities: A Field Study at the Basra University
Authors: Allawi Al-Saad Prof. Dr. Muslim
Published: May 2022

Education in general and university education in particular play a pivotal role in educational field. Universities play a major role in societies in general, because they participate directly to generation of new knowledge, and because they educate and shape the young generation to be leaders, entrepreneurs, scientists, and professionals in all fields of knowledge. Therefore, it is necessary to be careful when adopting the university governance system in Iraqi universities, in a way that helps to use all the principles and requirements of university governance in the correct way when implementing. The (university governance screening card) is the most suitable for assessing the reality of university governance, and for revealing the details required by the implementation process the purpose of the research paper is to explore the actual reality of the level of governance implementation in the Iraqi University in comparison with the five dimensions of the university governance screening modified card. The University of Basra was chosen as a field of study. The community was identified with highly qualified and experienced teachers. For data collection purposes, a checklist consisting of a three-point scale was used. To measure the level of opinions of the sample members on each clause or dimension, the evaluation revealed that Basra University needed many procedures’ to build an integrated governance system.
La Medicina del Viajero en República Dominicana
Authors: Castillo Santana Esmailyn , De Jesús Arámboles Yocastia , Catoia Varela Margareth , Bautista Branagan Claudio E. , Lara Reyes Eudy M. , Dias da Costa Marcellus
Published: May 2022

Introducción: la especialidad Medicina del Viajero existe hace más de 40 años. Sin embargo, esta es prácticamente desconocida por los dominicanos a pesar de la gran cantidad de personas que viajan desde y hacia nuestro país.

Material y métodos: Con el objetivo de determinar el conocimiento de los dominicanos sobre la existencia de la Medicina del Viajero y sus actitudes en relación a esta, realizamos una encuesta virtual de 8 preguntas, de la cual participaron 2,584 dominicanos.

Resultados: a pesar de que más del 80 % de los encuestados sabían que para viajar a determinados países debían tomar ciertas vacunas, menos del 25 % había escuchado hablar de la especialidad Medicina del Viajero. Tras conocer la definición y objetivos de la especialidad más del 90 % de los participantes consideró importante realizar una consulta previa al viaje con un especialista.

Conclusión: el desconocimiento de la especialidad y la ausencia de este servicio en el sistema público de salud son las principales barreras para el acceso de los dominicanos a la consulta de Medicina del Viajero. Es necesario dar a conocer la especialidad, utilizando evidencia científica y tomando como ejemplo la difusión mundial de la COVID-19 a través de los viajeros, concienciar a la población de la importancia de la consulta pre y post viaje, así como la creación de este servicio en hospitales públicos.
Conocimientos, percepciones, necesidades y desafíos de los adolescentes dominicanos con Diabetes Mellitus Tipo 1
Authors: Moore de Peralta Arelis , Cepeda Jenny , Abreu Rodríguez Gabriela
Published: May 2022

Introducción: el descontrol metabólico en pacientes con diabetes tipo 1 (DMT1) puede provocar complicaciones severas y reducir la esperanza de vida. La transición a la adolescencia en jóvenes con DMT1 determina cambios importantes que pueden influenciar negativamente el control metabólico.

Propósito: determinar el nivel de conocimiento, las percepciones, las necesidades y los desafíos de los adolescentes dominicanos con DMT1.

Metodología: entrevistas telefónicas a adolescentes con DMT1, entre 14 y 18 años. El análisis incluyó la codificación con base al Modelo de Creencias de Salud, utilizando NVivo, a través de un abordaje deductivo e inductivo.

Resultados: participantes reportaron un alto nivel de susceptibilidad percibida de sufrir complicaciones y una percepción de severidad asociada a una enfermedad incurable que causa complicaciones severas. En los factores modificadores se destacan determinantes sociales como el nivel socioeconómico de la familia y, en las variables externas, el rol de las redes de apoyo en el manejo de la enfermedad.

Conclusiones: se requieren intervenciones culturalmente relevantes para mejorar el control metabólico y los aspectos psicosociales en los adolescentes dominicanos con DMT1, como sería una aplicación móvil para el automanejo; además, incorporar las perspectivas, las realidades contextuales y los conocimientos de los adolescentes en las estrategias de educación terapéutica sobre la DMT1 favorecería su impacto.
Incidencia de cardiopatías congénitas en pacientes ingresados en la unidad de Neonatología del Hospital Infantil Robert Reid Cabral, 2016-2018
Authors: Mancebo García Pablo , Soriano Nathalie , Lazala Leyni E. , Contreras Elizabeth , Haché Caran , Malagón Lissette
Published: May 2022

Introducción: las cardiopatías congénitas son alteraciones estructurales del corazón y/o grandes vasos que se desarrollan durante la embriogénesis, existe un aumento aparente de la incidencia de las cardiopatías congénitas (CC) en las investigaciones recientes, especialmente de las cardiopatías acianógenas, como la comunicación interventricular (CIV) e interauricular (CIA), así como en menor grado otras cardiopatías, como transposición de grandes vasos (TGV) y el síndrome de corazón izquierdo hipoplásico (SCIH).

Material y métodos: estudio observacional, descriptivo, transversal y retrospectivo sobre la incidencia de cardiopatías congénitas en pacientes ingresados en la Unidad de Neonatología del Hospital Infantil Robert Reid Cabral durante el período 2016-2018 (hasta la semana epidemiológica #38). La muestra fue de 76 pacientes (n=76).

Resultados: la incidencia de cardiopatías congénitas fue 4.97 %. El 59.2 % eran masculino. Mas de 65 % de pacientes procedían de la región este del país. La disnea representó más de 70 % de los motivos de consulta, seguida de cianosis. 35.5 % de las cardiopatías correspondieron a CIV, que fue la patología cardíaca congénita más frecuentemente presentada, seguida por CIA.

Conclusión: observamos una incidencia global de cardiopatías congénitas de 4.97 % con predominio en sexo masculino. Los pacientes procedían de la región este en más de la mitad de los casos, y presentaron con mayor frecuencia disnea como motivo de consulta. La incidencia más elevada de cardiopatía congénita fue la CIV.
Atipicidad en el hipotiroidismo congénito: síndrome de Kocher-Debré-Semelaigne. Reporte de caso
Authors: Pérez Gesen Cecilia , Fernández Patty Bonna Viviana , Olivares Torres Ana , Carvajal Martinez Francisco , Pedroso Vila Raiza , Masot Rangel Antonio , Navarrete Cabrera Juliette
Published: May 2022

El síndrome de Kocher Debré Semelaigne (SKDS) se describe dentro de las formas clínicas atípicas asociadas al hipotiroidismo congénito (HC) severo, no tratado y de larga evolución, con manifestaciones de pseudohipertrofia muscular difusa y debilidad muscular predominantemente proximal, reversible al reemplazo con tiroxina. Es raro en países con programas de pesquisa neonatal.

Objetivo: reportar el caso de un niño con diagnóstico de HC por disembriogenesis (atireosis), que se mantuvo con mal control de la enfermedad durante el primer año de vida y manifestaciones miopáticas desde la etapa neonatal.

Resultados: se confirma el diagnóstico a través de estudios específicos, con evidencias de patrones miopáticos característicos. Se logra regresión clínica parcial a los nueve meses de mantener estabilidad de la TSH y las hormonas tiroideas (HT), coincidiendo con la normalización de la enzima de músculo creatinfosfoquinasa (CPK). A los 12 años de seguimiento, mantenía ligera hipertrofia de la musculatura de las extremidades superiores, dorsales y glúteos, a pesar de mantenerse eutiroideo.

Conclusiones: la presencia de hipertrofia muscular debe considerarse un dato clínico de sospecha de hipotiroidismo, aun con la implementación de los programas de pesquisa neonatal. Es posible la regresión parcial de la pseudohipertrofia muscular con el restablecimiento de la función tiroidea. Se debe tomar en cuenta en el diagnóstico diferencial de otras miopatías primarias.
DIAGNOSTIC EFFECTIVENESS OF A NEW METHOD FOR DETERMINING KIDNEY DAMAGE IN CHRONIC HEART FAILURE
Authors:   Belarusian Medical Academy of Post-Graduate Education, Zherko O.M.
Published: May 2022

Objectives. To evaluate diagnostic effectiveness of a complex ultrasound method for determining kidney damage in patients with chronic heart failure (CHF). Material and methods. In 2017-2021 on the basis of the Healthcare Institution «1st City Clinical Hospital» in Minsk, a clinical and instrumental study was performed on 203 patients aged 66 (59; 75) years, of which 111 (54.7%) were women and 92 (45.3%) men. Dynamic ultrasound investigation of the kidneys was carried out in 80 patients with CHF after ≥3 months. Inclusion criteria: sinus rhythm in patients; essential (primary) arterial hypertension; chronic ischemic heart disease; congestive heart failure; informed voluntary consent of the patient to participate in the study. Exclusion criteria: glomerular, tubulointerstitial kidney disease, obstructive uropathy, renal artery stenosis, congenital kidney diseases, history of renal malignancy. Results. The method for determining kidney damage in CHF is based on the concept of establishing a complex of ultrasound signs. It includes an assessment of the total volume of the kidneys, parenchymal thickness, end diastolic blood flow velocity, pulsation index, resistance index in segmental renal arteries, and characterizes kidney damage in patients with normal or slightly reduced glomerular filtration rate (GFR) (categories C1 - C2), chronic kidney disease (CKD) with categories of GFR C3A - C4 and CHF. Conclusions. The method has a high accuracy - 98.3%, which makes it possible to recommend its use when establishing CKD in patients with CHF.
PATRIOTS-DOCTORS OF VITEBSK STATE MEDICAL INSTITUTE DURING THE YEARS OF THE GREAT PATRIOTIC WAR
Authors:   Vitebsk State Order of Peoples' Friendship Medical University, Vasilenko N.I. , Kadushko R.V. ,   Vitebsk State Order of Peoples' Friendship Medical University, Myasoedov A.M. ,   Vitebsk State Order of Peoples' Friendship Medical University, Pogotsky A.K. ,   Vitebsk State Order of Peoples' Friendship Medical University
Published: May 2022

The given article on the example of the activities of the staff members of Vitebsk State Medical Institute during the years of the Great Patriotic War facilitates the formation of citizenship, patriotism, universal human values in the student youth, cultivates respect for the profession of medical workers who have made a huge contribution to the victory gained in the Great Patriotic War, shows their heroism and self-sacrifice. The role of VSMU museum in the education of student youth during their studying at the university is defined. Forms and methods of the work of public organizations (Trade Union, Veterans Council, Belarusian Republican Youth Union, Belarusian Union of Women) of the Educational Establishment «Vitebsk State Order of Peoples' Friendship Medical University» and those of student academic group tutors are revealed.
A extensão no curso de medicina como estratégia de formação para o Sistema Único de Saúde (SUS)
Authors: Lemos Marcio , Arcangelis Adriana , Arcangelis Flávio
Published: May 2022

Este relato tem por objetivo descrever a experiência de um projeto de extensão desenvolvido pelo curso de medicina da Universidade Federal de Sergipe, campus Lagarto. As atividades de ensino-aprendizagem tiveram o intuito de levar os estudantes a analisar criticamente as políticas e práticas de saúde desenvolvidas no âmbito da comunidade e das instituições estatais de saúde, constituindo-se um espaço de experimentação de práticas inovadoras a partir da adoção de metodologias de ensino-aprendizagem centradas no aluno, conforme orientado pelas Diretrizes Curriculares Nacionais. A implementação do programa contemplou ações envolvendo análise de documentos oficiais (leis e portarias) sobre as mudanças do novo modelo de financiamento de custeio da Atenção Primária à Saúde, a criação de um espaço de discussão virtual com as equipes de saúde e a produção de materiais informativos (físicos e virtuais), como vídeos e cartilhas. A realização do projeto apoiado na experiência de integração ensino-serviço-comunidade contribuiu para o esclarecimento de gestores e trabalhadores da área sobre as mudanças em curso, bem como para o desenvolvimento, nos discentes envolvidos, de competências tecnológicas e críticas focadas na qualidade do cuidado e voltadas à melhoria das condições de vida e saúde das populações. Esses fatores são concebidos como os principais paradigmas científicos atuais no campo das políticas públicas em saúde para superação de modelos de ensino que se mostram cada vez mais incapazes de atender à amplitude das necessidades sociais de saúde.
SPECIFICS OF MILITARY-TECHNICAL POLICY OF MODERN RUSSIA
Authors:   Chelyabinsk State University, Stezhko V.V.
Published: May 2022

The specifics of the implementation of military-technical cooperation as one of the main directions of military-technical policy are shown. The analysis of the model of military-technical policy in the form of a system of interaction of its objects is given. The current state of military-technical policy is determined.
POTENCIAL ENERGÉTICO DO METANO ESTIMADO A PARTIR DOS RESÍDUOS ORGÂNICOS GERADOS NA CEASA DO MUNICÍPIO DE SÃO LUÍS, MA
Authors: Marte Clara da Penha , Campelo Lara Rosa Carvalho , De Jesus Welcky Breno da Silva , Lobato Maxwell Ferreira
Published: May 2022

O descarte incorreto de frações orgânicas em locais inadequados ocasiona impactos negativos ao meio ambiente, entre eles, a geração de gases de efeito estufa, como o metano, além de trazer prejuízos econômicos. Conhecendo as orientações da Política Nacional de Resíduos Sólidos por meio da Lei Federal n° 12.305/2010, visando a destinação adequada e o reaproveitamento dos resíduos orgânicos, faz-se necessário a reutilização desses resíduos via digestão anaeróbia. Com isso, o objetivo deste trabalho foi estimar o potencial de geração de energia através do processo de biodigestão dos resíduos orgânicos gerados na CEASA-MA, no município de São Luís. Os resultados obtidos, mostram que a geração de resíduos orgânicos em 2020 foi de 2.321,66 T, o que equivale a produção de 585,18m3 de CH4/dia. A análise mostrou que inicialmente será necessário o investimento de um valor maior, mas que a longo prazo a CEASA economizará cerca de R$339.426, 45/ano e não precisará ter altos gastos desnecessários, como o transporte dos resíduos até o Aterro Sanitário Titara, situado no município de Rosário-MA, corroborando a aplicabilidade de um aparelho biodigestor na Central.
Analysis of fatigue crack growth in polymers using the two-parametric approach
Authors: Sadananda K. , Iyyer Nagaraja , Vasudevan A.K. , Babu M. Nani , Phan Nam , Rahman A.
Published: May 2022

Considering that the correct quantification of fatigue damage involves
two load parameters, the available load ratio data on polymeric
materials are analyzed. It is shown that crack growth can be
characterized by two parameters, ΔK and K , without
the need for any crack closure concept. The crack growth rates, starting
from the threshold can be represented by the L-shaped curves in the ΔK-K
plane defining two limiting variables, ΔK* and K
*. Crack growth trajectory maps for various materials
are developed by plotting ΔK* versus K *, as a
function of crack growth rate. The trajectory defines the crack growth
resistance curve providing a measure of material resistance to
increasing crack tip driving forces.
Polysorbate identity and quantity dictates the extensional flow properties of protein-excipient solutions
Authors: Lauser Kathleen , Rueter Amy , Calabrese Michelle
Published: May 2022

While protein medications are promising for treatment of cancer and
autoimmune diseases, challenges persist in terms of development and
injection stability of high-concentration formulations. Here, the
extensional flow properties of protein-excipient solutions are examined
via dripping-onto-substrate (DoS) extensional rheology, using a model
ovalbumin protein (OVA) and biocompatible excipients polysorbate 20
(PS20) and 80 (PS80). Despite similar PS structures, differences in
extensional flow are observed based on PS identity in two regimes: at
moderate total solution concentrations where surface tension differences
drive changes in extensional flow behavior, and at small PS:OVA ratios,
which impacts the onset of weakly elastic behavior. Undesirable
elasticity is observed in ultra-concentrated formulations, independent
of PS identity; higher PS contents are required to observe these effects
than with analogous polymeric excipient solutions. These studies reveal
novel extensional flow behaviors in protein-excipient solutions, and
provide a straightforward methodology for assessing the extensional flow
stability of new protein-excipient formulations.
The American Brodsky: A Research Overview
Authors: BERLINA ALEXANDRA
Published: May 2022

A Russian-American poet and essayist, a Nobel laureate, Joseph Brodsky is hardly present on the map of American studies. The following overview attempts to provide materials for remedying this oversight. After all, though the overwhelming majority of Brodsky scholars are Slavists, valuable work on Brodsky in an American context has been done, and a substantial part of it has been published in English. After a short biographical excursion, the materials are assembled according to the following categories: “Brodsky in America,” “Brodsky and American Literature,” “Brodsky as an American Poet,” and “Brodsky's Self-Translations into English.” In 2016, twenty years after his death in New York, the time seems ripe for a reconsideration.
An Amateur “Sun Also Rises”
Authors: DAIKER DONALD A.
Published: May 2022

This is the first new edition of Hemingway's The Sun Also Rises since its publication in 1926. A visually attractive and readable volume, it includes useful material such as early drafts of the novel and the discarded opening chapter that Hemingway cut at the urging of F. Scott Fitzgerald. What is disappointing is what is missing, notably a statement of editorial principles, as well as footnotes elucidating dated references and now-obscure allusions. Unfortunately, this “new” Sun has been edited, not by scholars, not by the professionals whom Hemingway admired, but by amateurs—family members who have not bothered to keep current with Hemingway scholarship and criticism. Not only are “Works Cited” and “Suggestions for Further Reading” lacking; so is any recognition in editor Seán Hemingway's “Introduction” that new and persuasive readings of Sun have emerged in the last quarter century.
Mailer Unbound
Authors: BROER LAWRENCE R.
Published: May 2022

According to Fitzgerald, “There never was a good biography of a good novelist. There couldn't be. He is too many people if he's any good” (qtd. in Wilson, The Crack-Up 177). Yet it would be hard to imagine a better told writer's life than J. Michael Lennon's Norman Mailer (2013). When Mailer directed his friend and longtime scholar of his work to feel free to put in everything, Lennon did just that—at least everything relating to Mailer's work as psycho-autobiography. We knew Mailer's work was intensely personal, but now we know the unique nature of Mailer's fictional self-revelations; they are a continuous working out of complex psychological oppositions at the heart of what Lennon aptly calls Mailer's “double life.” Lennon's Mailer reads like one of Mailer's own absorbing journalistic books. It will prove invaluable to readers hoping better to understand and to evaluate the author's place in American literature.
A Forgotten Writer: Alice Beal Parsons and “Cross Purposes”
Authors: HOLMES SARAH C.
Published: May 2022

This essay recovers a socialist and feminist writer previously overlooked by literary scholars. An author of five novels and numerous short stories, Alice Beal Parsons published for both mainstream and progressive audiences. Of particular note is her membership in the Communist Labor Party and her renunciation of a bourgeois identity. The archival discovery “Cross Purposes” is a good representation of her commitment to radicalism. Most likely composed in the 1920s or 1930s, the short story is a unique examination of a wealthy woman's role in the oppression of the women who work for her. Included with a full transcription of the story is a bibliography of Parsons's major work.
Too Much of a Good Thing Is Wonderful: At Long Last, Cather's Letters
Authors: LINDEMANN MARILEE
Published: May 2022

This review essay explores the profound scholarly significance of the publication of The Selected Letters of Willa Cather, a nearly 700-page collection scrupulously edited by Andrew Jewell and Janis Stout (Knopf, 2013). The volume contains 566 full-text transcriptions selected from the 3,000 Cather letters now known to exist and makes them accessible in print for the first time. Cather's will, executed in 1943, forbade not only publication of her letters but even direct quotation from them, so biographers and critics for decades engaged in a kind of shadowboxing as they sought to convey Cather's thoughts and feelings through the awkward constraint of paraphrase. Now that the testamentary restrictions have been lifted and this volume is available, scholars and fans can hear Cather's epistolary voice without traveling to archives. An extraordinary contribution to Cather studies, the Selected Letters offers much to anyone interested in twentieth-century American literature, women writers, or LGBT/queer studies.
Perancangan Sistem Monitoring Dan Kontrolling Suhu Dan Kadar Gas Ammonia Pada Kandang Ayam Berbasis Mikrokontroller NodeMCU
Authors: Bilal Muhammad , Umar U
Published: May 2022

Ayam broiler merupakan jenis ayam pedaging yang dimana sebagai penghasil daging ayam dengan konversi pakan yang rendah, yang menjadikan ayam jenis ini dijadikan sebagai lahan bisnis yang bagus dan menjanjikan. Walaupun ayam broiler merupakan salah satu lahan bisnis yang bagus dan diharapkan akan tetapi, di peternakan Indonesia, terutama di kandang-kandang perumahan masih memiliki beberapa masalah. Salah satunya adalah bau kandang yang menyengat hal ini karena tidak adanya suhu dan kadar gas amonia pada kandang ayam. Bau kandang yang menyengat oleh naiknya kadar gas amonia karena pengaruh suhu yang tidak ideal, yang dimana hal ini dapat mempengaruhi kinerja hewan ternak dari proses pertumbuhan hingga proses. Jika suatu kandang ternak tidak ada pada kondisi berkala maka pada suhu dan gas amonia pada kandang ayam dapat mengakibatkan kematian bagi hewan ternak. Berdasarkan permasalahan tersebut penulis merancang sistem pemantauan dan pengendalian suhu dan kadar gas amonia pada kandang ayam berbasis mikrokontroller NodeMcu. Alat yang dibuat ini menggunakan beberapa komponen yaitu NodeMCU ESP8266 sebagai mikrokontroller, untuk sensor dan aktuator menggunakan DHT11, MQ135, LCD 16x2, Relay 2 channel, DC Fans, dan platform Antares. Hasil pembacaan dari sensor DHT11 dan MQ135 ini akan dimonitoring dan dikirim ke database Antares dan hasil outputnya akan ditampilkan melalui LCD 16x2, secara bersamaan mikrokontroller Node MCU akan mengirimkan perintah ke relay untuk menghidupkan DC fans. DC fans akan bekerja jika sensor suhu dan ammonia membaca nilai lebih dari atau sama dengan 30 ℃ dan 20 ppm (part per million), dan DC fans akan berhenti bekerja jika sensor membaca di bawah dari 30 ℃ dan 20 ppm.
Sistem Pemantauan dan Pengendalian Penggunaan Air Menggunakan Aplikasi Telegram Berbasis IoT
Authors: Rohmah Ratnasari Nur , Budiman Aris , Rohman Vebri Latiefudin
Published: May 2022

Penelitian ini mendisain sebuah alat untuk pengendalian dan pemantauan penggunaan air berbasis Internet of things. Alat yang didisain terdiri dari komponen dasar: sensor, pewaktu real time (rtc), relay, solenoid, LCD 16x2 dan NodeMCU. Alat akan membaca penggunaan air dengan sensor aliran air yang hasilnya akan di tampilkan di LCD 16x2. Selain ditampilkan, hasil dikirim ke aplikasi telegram pada telepon genggam. Fungsi pengendali penggunaan air dilakukan dengan mengendalikan buka/tutup kran air. Sebagai pelengkap,alat juga dilengkapi kendali otomatis yang akan menutup keran pada level tertentu. Hasil pengujian alat menunjukkan, monitoring dan pengendalian kran air melalui telepon genggam telah berjalan seperti yang dirancang. Sedangkan hasil dari kalibrasi Sensor Water Flow dibandingkan dengan gelas ukur mperlihatkan eror rata-rata errornya 1,9%. Dan hasil dari pengujian Sensor Water Level untuk kendali otomatis memperlihatkan kesalahan relatif rata-rata sebesar 10,3%.
Perancangan Chatbot Islami untuk Aplikasi ChatAja
Authors: Pratama Nanda Yusuf Nur , Al Irsyadi Fatah Yasin
Published: May 2022

ChatAja adalah platform komunikasi karya anak bangsa yang dibuat untuk melengkapi gaya hidup digital dengan menyediakan layanan pesan instant, pesan suara, dan panggilan video gratis. ChatAja dirilis ke publik pada bulan februari 2020 dan dapat diinstall di ponsel android maupun iphone. Seperti kebanyakan aplikasi pesan instant ChatAja juga memiliki fitur chatbot. Chatbot adalah program komputer yang diprogram untuk dapat membalas pesan pengguna secara otomatis dan natural. Ada banyak chatbot yang telah dibuat oleh tim ChatAja dengan berbagai kegunaan untuk membantu penggunanya. Karena merupakan aplikasi yang tergolong baru ChatAja memerlukan banyak inovasi agar dapat diterima oleh masyarakat. Oleh karena itu untuk menyambut datangnya bulan suci ramadhan ChatAja ingin membuat sebuah chatbot yang dapat membantu penggunanya dalam menjalankan ibadah di bulan suci ramadhan. Penelitian ini bertujuan untuk mengembangkan sebuah chatbot sebagai media promosi aplikasi ChatAja dan juga untuk membantu penggunanya memeriahkan bulan suci ramadhan. Chatbot ini dirancang dengan menggunakan bahasa pemrograman javascript dengan framework Node JS untuk chatbot,  bahasa pemrograman Ruby dengan framework Ruby on Rails untuk web admin dari chatbot dan Postgree SQL sebagai sistem manajemen basis data. Pengembangan chatbot ini menggunakan metode waterfall dengan tahapan analisis kebutuhan, perancangan sistem, pembuatan sistem, pengujian sistem, implementasi dan perawatan sistem. Dalam pengembangannya chatbot memiliki 4 fitur utama yaitu adzan checker, onde day one ayat, kuis ramadhan dan reminder. Berdasarkan hasil pengujian blackbox dan UAT dapat disimpulkan bahwa sistem berjalan dengan normal serta memperoleh hasil rata-rata persentase dari responden sebesar 84,4%. Dari pengujian tersebut dapat disimpulkan bahwa sistem dapat digunakan sebagai media promosi aplikasi ChatAja Messanger.
Monitoring dan Controlling Kadar Ph pada Air Kolam Ikan dengan Menggunakan Aplikasi Blynk Berbasis Esp Node Mcu
Authors: Jeprianto Riki , Rohmah Ratnasari Nur
Published: May 2022

Sebagian besar masyarakat Indonesia sangat suka mengkonsumsi berbagai macam jenis ikan karena sangat mudah sekali ditemukan di Indonesia dan banyak pula petani yang membudidayakannya, mulai dari ikan lele, nila, kakap dan sebagainya. Cara budidaya ikan pun terbilang mudah, namun ada kalanya petani harus sedikit usaha untuk memantau kualitas air baik itu keasaman (pH), tingkat kekeruhan dalam kolam dan suhu air kolam secara manual menggunakan alat ukur. Pengisian kolam dan pengurasan kolam pun dilakukan dengan menghidupkan pompa terlebih dahulu sehingga kurang efektif. Penulis ingin mengembangkan peralatan yang dapat digunakan untuk mempermudah petani dalam memonitoring kualitas air, kendali dan mengisi dan menguras kolam berbasis Internet Of Things dengan memanfaatkan aplikasi Blynk. Sistem ini dibuat menggunakan ESP Node MCU sebagai microcontroller, Sensor pH, Sensor Turbidity dan Sensor Suhu. Komponen pendukung lainnya adalah adaptor, water pump, relay dua channel dan selang air. Hasil pembacaan akan ditampilkan pada aplikasi Blynk yang nantinya dapat memberikan perintah sesua dengan tombol yang tersedia. Keadaan kolam secara real time dapat diketahui petani dengan mudah, mampu memberikan kontrol sederhana melalui kontrol aplikasi Blynk.