bluuebunny/crossref_metadata_2025 huggingface dataset:
Optical Properties of Tensilely Strained Ge Nanomembranes
Authors: Paiella Roberto , Lagally Max G.
Published: June 2018

Group-IV semiconductors, which provide the leading materials platform of micro- electronics, are generally unsuitable for light emitting device applications because of their indirect- bandgap nature. This property currently limits the large-scale integration of electronic and photonic functionalities on Si chips. The introduction of tensile strain in Ge, which has the effect of lowering the direct conduction-band minimum relative to the indirect valleys, is a promising approach to address this challenge. Here we review recent work focused on the basic science and technology of mechanically stressed Ge nanomembranes, i.e., single-crystal sheets with thicknesses of a few tens of nanometers, which can sustain particularly large strain levels before the onset of plastic deformation. These nanomaterials have been employed to demonstrate large strain-enhanced photoluminescence, population inversion under optical pumping, and the formation of direct-bandgap Ge. Furthermore, Si-based photonic-crystal cavities have been developed that can be combined with these Ge nanomembranes without limiting their mechanical flexibility. These results highlight the potential of strained Ge as a CMOS-compatible laser material, and more in general the promise of nanomembrane strain engineering for novel device technologies.
Dose- and Time-Dependent Cytotoxicity of Layered Black Phosphorus in Fibroblastic Cells
Authors: Song Su-Jin , Shin Yong , Lee Hyun , Kim Bongju , Han Dong-Wook , Lim Dohyung
Published: June 2018

Black phosphorus (BP) is a monolayer/multilayer two-dimensional (2D) nanomaterial, which has recently emerged as one of the most attractive 2D nanomaterials due to its fascinating physicochemical and optoelectronical properties. Layered BP may have promising applications in biomedical fields, such as drug delivery, photodynamic/photothermal therapy and bioimaging, although its intrinsic toxicity has not been fully elucidated yet. In the present study, the cytotoxicological effects of layered BP on both cell metabolic activity and membrane integrity were investigated. Layered BPs were prepared using a modified ultrasonication-assisted solution method, and their physicochemical properties were characterized. The dose- and time-dependent cytotoxicity of layered BP was assessed against L-929 fibroblasts. Our findings indicate that the cytotoxicity of BPs is proportionally dependent on their concentration and exposure time, which is affected by the oxidative stress-mediated enzyme activity reduction and membrane disruption. On the other hand, layered BPs did not exhibit significant cytotoxicity at concentrations lower than 4 μg/mL. Therefore, it is suggested that layered BPs can be effectively utilized as therapeutic delivery carriers and imaging agents.
Facile Fabrication of Highly Active Magnetic Aminoclay Supported Palladium Nanoparticles for the Room Temperature Catalytic Reduction of Nitrophenol and Nitroanilines
Authors: Jia Lei , Zhang Wensheng , Xu Jun , Cao Jianliang , Xu Zhouqing , Wang Yan
Published: June 2018

Magnetically recyclable nanocatalysts with excellent performance are urgent need in heterogeneous catalysis, due to their magnetic nature, which allows for convenient and efficient separation with the help of an external magnetic field. In this research, we developed a simple and rapid method to fabricate a magnetic aminoclay (AC) based an AC@Fe3O4@Pd nanocatalyst by depositing palladium nanoparticles (Pd NPs) on the surface of the magnetic aminoclay nanocomposite. The microstructure and the magnetic properties of as-prepared AC@Fe3O4@Pd were tested using transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), and vibrating sample magnetometry (VSM) analyses. The resultant AC@Fe3O4@Pd nanocatalyst with the magnetic Fe-based inner shell, catalytically activate the outer noble metal shell, which when combined with ultrafine Pd NPs, synergistically enhanced the catalytic activity and recyclability in organocatalysis. As the aminoclay displayed good water dispersibility, the nanocatalyst indicated satisfactory catalytic performance in the reaction of reducing nitrophenol and nitroanilines to the corresponding aminobenzene derivatives. Meanwhile, the AC@Fe3O4@Pd nanocatalyst exhibited excellent reusability, while still maintaining good activity after several catalytic cycles.
Short-Term Exposure to High Sucrose Levels near Weaning Has a Similar Long-Lasting Effect on Hypertension as a Long-Term Exposure in Rats
Authors: Villegas-Romero Mariana , Castrejón-Téllez Vicente , Pérez-Torres Israel , Rubio-Ruiz María Esther , Carreón-Torres Elizabeth , Díaz-Díaz Eulises , Del Valle-Mondragón Leonardo , Guarner-Lans Verónica
Published: June 2018

Adverse conditions during early developmental stages permanently modify the metabolic function of organisms through epigenetic changes. Exposure to high sugar diets during gestation and/or lactation affects susceptibility to metabolic syndrome or hypertension in adulthood. The effect of a high sugar diet for shorter time lapses remains unclear. Here we studied the effect of short-term sucrose ingestion near weaning (postnatal days 12 and 28) (STS) and its effect after long-term ingestion, for a period of seven months (LTS) in rats. Rats receiving sucrose for seven months develop metabolic syndrome (MS). The mechanisms underlying hypertension in this model and those that underlie the effects of short-term exposure have not been studied. We explore NO and endothelin-1 concentration, endothelial nitric oxide synthase (eNOS) expression, fatty acid participation and the involvement of oxidative stress (OS) after LTS and STS. Blood pressure increased to similar levels in adult rats that received sucrose during short- and long-term glucose exposure. The endothelin-1 concentration increased only in LTS rats. eNOS and SOD2 expression determined by Western blot and total antioxidant capacity were diminished in both groups. Saturated fatty acids and arachidonic acid were only decreased in LTS rats. In conclusion, a high-sugar diet during STS increases the hypertension predisposition in adulthood to as high a level as LTS, and the mechanisms involved have similarities (participation of OS and eNOS and SOD expression) and differences (fatty acids and arachidonic acid only participate in LTS and an elevated level of endothelin-1 was only found in LTS) in both conditions. Changes in the diet during short exposure times in early developmental stages have long-lasting effects in determining hypertension susceptibility.
Serum Magnesium after Kidney Transplantation: A Systematic Review
Authors: Garnier Anne-Sophie , Duveau Agnès , Planchais Martin , Subra Jean-François , Sayegh Johnny , Augusto Jean-François
Published: June 2018

Magnesium (Mg) status has recently drawn close attention in chronic kidney disease and in kidney transplant recipients. This review aims to evaluate the body of evidence linking hypomagnesemia to clinical consequences in these specific populations. After a brief summary of the main mechanisms involved in Mg regulation and of Mg status in end-stage renal disease, the review focuses on the relationship between hypomagnesemia and cardiovascular risk in kidney transplant recipients. A body of evidence in recent studies points to a negative impact of hypomagnesemia on post-transplant diabetes mellitus (PTDM) and cardiovascular risk, which currently represent the main threat for morbidity and mortality in kidney transplantation. Deleterious biological mechanisms induced by hypomagnesemia are also discussed. While data analysis enables us to conclude that hypomagnesemia is linked to the development of PTDM, studies prospectively evaluating the impact of hypomagnesemia correction after kidney transplantation are still lacking and needed.
Fetal Hepatic Response to Bovine Viral Diarrhea Virus Infection in Utero
Authors: Morarie-Kane Susan E. , Smirnova Natalia P. , Hansen Thomas R. , Mediger Jessica , Braun Lyle , Chase Christopher
Published: June 2018

Non-cytopathic bovine viral diarrhea virus (ncp BVDV) can cause persistent infection (PI) in animals infected in utero during early gestation. PI animals shed the virus for life and are the major source of the virus in herds. The mechanism responsible for BVDV immune tolerance in the PI fetus is unknown. We assessed the impact of BVDV infection on the fetal liver. Dams were inoculated with ncp BVDV at gestational day 75. Fetal liver samples were collected at necropsy, 7 and 14 days post-maternal-BVDV inoculation. BVDV antigen was not detected in the liver at gestational day 82 (7 days post-maternal inoculation). However, at 14 days post-maternal inoculation, BVDV was detected by immunohistochemistry in fetal Kupffer cells. Flow cytometry analysis showed a higher percentage of hepatic immune cells expressed MHC I and MHC II in BVDV-infected fetal liver (as compared to uninfected controls). Immunofluorescence was used to identify Kupffer cells, which were positive for BVDV antigen, near populations of CD3+ lymphocytes. The identification of BVDV in the fetal liver Kupffer cells at 14 days post inoculation is interesting in the context of establishment of tolerance in persistent infection. These data indicate the presence of a hepatic immune response to fetal infection.
DNA Barcoding to Confirm the Morphological Identification of the Coral Trees (Erythrina spp., Fabaceae) in the Ancient Gardens of Naples (Campania, Italy)
Authors: De Luca Adriana , Sibilio Giancarlo , De Luca Paolo , Del Guacchio Emanuele
Published: June 2018

The coral trees (genus Erythrina) have been fostering great interest among the botanists and gardeners of Naples, since their arrival in Europe in the second half of the 18th century. Numerous species were present in the royal and private botanical gardens of the region, but their number has decreased today. The purpose of this work was to verify which species occur nowadays in the public areas of Naples and associate them with the historical information about their introduction. The identification was carried out also by molecular methods, by means of sequencing nuclear and chloroplast DNA markers. The comparison of the sequences obtained for the specimens present in Naples with those present in the literature, together with a morphological examination, allowed us to identify with accuracy the species anciently introduced or nowadays cultivated in Naples.
Biological Activity of the Salvia officinalis L. (Lamiaceae) Essential Oil on Varroa destructor Infested Honeybees
Authors: Bendifallah Leila , Belguendouz Rachida , Hamoudi Latifa , Arab Karim
Published: June 2018

The present work is conducted as part of the development and the valorization of bioactive natural substances from Algerian medicinal and aromatic spontaneous plants, a clean alternative method in biological control. For this purpose, the bio-acaricidal activity of Salvia officinalis (sage)essential oil (EO)was evaluated against the Varroa destructor, a major threat to the honey bee Apis mellifera ssp. intermissa. The aerial parts of S. officinalis L., 1753 were collected from the Chrea mountainous area in Northern Algeria. They were subjected to hydro distillation by a Clevenger apparatus type to obtain the EO, and screened for bio-acaricidal activity against Varroa destructor by the method of strips impregnated with the mixture EO and twin according to three doses. Pre-treatment results revealed infestation rates in the experimental site ranging from 3.76% to 21.22%. This showed the heterogeneity of infestations in hives according to the density of bees. This constituted a difficulty in monitoring the population dynamics of this parasite. After treatment, a difference in the acaricidal effect of Sage essential oil is noticed. It gives a mortality rate of 6.09% by the dose D1: 5%, 2.32% by the dose D2: 15%, and a low mortality rate of 0.9% by the dose D3: 20%. The chemical treatment carried out by Bayvarol gives a result close to that of the essential oil of Sage (9.97%).These results point to the fact that Sage essential oil treatments have a significant effect and good biological activity with regard to harmful species.
Cellulose Aerogels: Synthesis, Applications, and Prospects
Authors: Long Lin-Yu , Weng Yun-Xuan , Wang Yu-Zhong
Published: June 2018

Due to its excellent performance, aerogel is considered to be an especially promising new material. Cellulose is a renewable and biodegradable natural polymer. Aerogel prepared using cellulose has the renewability, biocompatibility, and biodegradability of cellulose, while also having other advantages, such as low density, high porosity, and a large specific surface area. Thus, it can be applied for many purposes in the areas of adsorption and oil/water separation, thermal insulation, and biomedical applications, as well as many other fields. There are three types of cellulose aerogels: natural cellulose aerogels (nanocellulose aerogels and bacterial cellulose aerogels), regenerated cellulose aerogels, and aerogels made from cellulose derivatives. In this paper, more than 200 articles were reviewed to summarize the properties of these three types of cellulose aerogels, as well as the technologies used in their preparation, such as the sol–gel process and gel drying. In addition, the applications of different types of cellulose aerogels were also introduced.
Highly Efficient Flame Retardant Hybrid Composites Based on Calcium Alginate/Nano-Calcium Borate
Authors: Liu Zhenhui , Li Zichao , Zhao Xihui , Zhang Lei , Li Qun
Published: June 2018

Hybrid composites with low flammability based on renewable calcium alginate and nano-calcium borate were fabricated using an in situ method through a simple, eco-friendly vacuum drying process. The composites were characterized by X-ray diffractometry (XRD), Fourier transform infrared spectrum (FTIR), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The combustion behavior and flammability of the composites were assessed by using the limiting oxygen index (LOI) and cone calorimetry (CONE) tests. The composites showed excellent thermal stability and achieved nonflammability with an LOI higher than 60. Pyrolysis was investigated using pyrolysis–gas chromatography–mass spectrometry (Py-GC-MS) and the results showed that fewer sorts of cracking products were produced from the hybrid composites compared with the calcium alginate. A possible thermal degradation mechanism of composites was proposed based on the experimental data. The combined results indicate that the calcium borate had a nano-effect, accumulating more freely in the hybrid composites and contributing significantly to both the solid phase and gas phase, resulting in an efficient improvement in the flame retardancy of the composites. Our study provides a novel material with promising potentiality for flame retardant applications.
Utilizing Pansharpening Technique to Produce Sub-Pixel Resolution Thematic Map from Coarse Remote Sensing Image
Authors: Wang Peng , Wang Liguo , Wu Yiquan , Leung Henry
Published: June 2018

Super-resolution mapping (SRM) is a technique to obtain sub-pixel resolution thematic map (SRTM). Soft-then-hard SRM (STHSRM) is an important SRM algorithm due to its simple physical meaning. The soft classification errors may affect the SRTM derived by STHSRM. To overcome this problem, the maximum a posteriori probability (MAP) super-resolution then hard classification (MTC) algorithm has been proposed. However, the prior information of the original image is difficult to utilize in MTC. To solve this issue, a novel method based on pansharpening then hard classification (PTC) is proposed to improve SRTM. The pansharpening technique is applied to the original coarse image to obtain the improved resolution image by suppling more prior information. The SRTM is then derived from the improved resolution image by hard classification. Not only does PTC inherit the advantages of MTC that avoids soft classification errors, but it can also incorporate more prior information from the original image into the process. Experiments based on real remote sensing images show that the proposed method can produce higher mapping accuracy than the STHSRM and MTC. It is shown that the PTC has the percentage correctly classified (PCC) in the range from 89.62% to 95.92% for the experimental dataset.
Improved Hydrological Decision Support System for the Lower Mekong River Basin Using Satellite-Based Earth Observations
Authors: Mohammed Ibrahim Nourein , Bolten John D. , Srinivasan Raghavan , Lakshmi Venkat
Published: June 2018

Multiple satellite-based earth observations and traditional station data along with the Soil & Water Assessment Tool (SWAT) hydrologic model were employed to enhance the Lower Mekong River Basin region’s hydrological decision support system. A nearest neighbor approximation methodology was introduced to fill the Integrated Multi-satellite Retrieval for the Global Precipitation Measurement mission (IMERG) grid points from 2001 to 2014, together with the Tropical Rainfall Measurement Mission (TRMM) data points for continuous precipitation forcing for our hydrological decision support system. A software tool to access and format satellite-based earth observation systems of precipitation and minimum and maximum air temperatures was developed and is presented. Our results suggest that the model-simulated streamflow utilizing TRMM and IMERG forcing data was able to capture the variability of the observed streamflow patterns in the Lower Mekong better than model-simulated streamflow with in-situ precipitation station data. We also present satellite-based and in-situ precipitation adjustment maps that can serve to correct precipitation data for the Lower Mekong region for use in other applications. The inconsistency, scarcity, poor spatial representation, difficult access and incompleteness of the available in-situ precipitation data for the Mekong region make it imperative to adopt satellite-based earth observations to pursue hydrologic modeling.
Bidirectional Long Short-Term Memory Network for Vehicle Behavior Recognition
Authors: Zhu Jiasong , Sun Ke , Jia Sen , Lin Weidong , Hou Xianxu , Liu Bozhi , Qiu Guoping
Published: June 2018

Vehicle behavior recognition is an attractive research field which is useful for many computer vision and intelligent traffic analysis tasks. This paper presents an all-in-one behavior recognition framework for moving vehicles based on the latest deep learning techniques. Unlike traditional traffic analysis methods which rely on low-resolution videos captured by road cameras, we capture 4K ( 3840 × 2178 ) traffic videos at a busy road intersection of a modern megacity by flying a unmanned aerial vehicle (UAV) during the rush hours. We then manually annotate locations and types of road vehicles. The proposed method consists of the following three steps: (1) vehicle detection and type recognition based on deep neural networks; (2) vehicle tracking by data association and vehicle trajectory modeling; (3) vehicle behavior recognition by nearest neighbor search and by bidirectional long short-term memory network, respectively. This paper also presents experimental results of the proposed framework in comparison with state-of-the-art approaches on the 4K testing traffic video, which demonstrated the effectiveness and superiority of the proposed method.
Detecting and Monitoring the Flavor of Tomato (Solanum lycopersicum) under the Impact of Postharvest Handlings by Physicochemical Parameters and Electronic Nose
Authors: Xu Sai , Sun Xiuxiu , Lu Huazhong , Yang Hui , Ruan Qingsong , Huang Hao , Chen Minglin
Published: June 2018

The objective of this study was to detect and monitor the flavor of tomatoes, as impacted by different postharvest handlings, including chilling storage (CS) and blanching treatment (BT). CS tomatoes were stored in a refrigerator at 5 °C and tested at storage day 0, 3, and 7. BT tomatoes were dipped in 50 or 100 °C water for 1 min, and tested immediately. The taste, mouth feel, and aroma of tomatoes were evaluated by testing the total soluble solid content (TSS), titratable acidity (TA), ratio of TSS and TA (TSS/TA), firmness, and electronic nose (E-nose) response to tomatoes. The experimental results showed that the CS can prevent taste and firmness loss to a certain extent, but the sensory results indicated that CS accelerated flavor loss due to the TSS/TA of CS tomatoes increasing slower than control. The taste and firmness of tomatoes were impacted slightly by 50 °C BT, and were significantly impacted by 100 °C BT. Based on physicochemical parameters, different postharvest handling treatments for tomatoes could not be classified except for the 100 °C BT treated tomatoes, which were significantly impacted in terms of taste and mouth feel. The E-nose is an efficient way to detect differences in postharvest handling treatments for tomatoes, and indicated significant aroma changes for CS and BT treated tomato fruit. The classification of tomatoes after different postharvest handling treatments, based on comprehensive flavor (physicochemical parameters and E-nose combined data), is better than that based on single physicochemical parameters or E-nose, and the comprehensive flavor of 100 °C BT tomatoes changed the most. Even so, the tomato flavor change during postharvest handlings is suggested to be detected and monitored by single E-nose data. The E-nose has also been proved as a feasible way to predict the TSS and firmness of tomato fruit rather than TA or TSS/TA, during the postharvest handing process.
Depletion-of-Battery Attack: Specificity, Modelling and Analysis
Authors: Shakhov Vladimir , Koo Insoo
Published: June 2018

The emerging Internet of Things (IoT) has great potential; however, the societal costs of the IoT can outweigh its benefits. To unlock IoT potential, there needs to be improvement in the security of IoT applications. There are several standardization initiatives for sensor networks, which eventually converge with the Internet of Things. As sensor-based applications are deployed, security emerges as an essential requirement. One of the critical issues of wireless sensor technology is limited sensor resources, including sensor batteries. This creates a vulnerability to battery-exhausting attacks. Rapid exhaustion of sensor battery power is not only explained by intrusions, but can also be due to random failure of embedded sensor protocols. Thus, most wireless sensor applications, without tools to defend against rash battery exhausting, would be unable to function during prescribed times. In this paper, we consider a special type of threat, in which the harm is malicious depletion of sensor battery power. In contrast to the traditional denial-of-service attack, quality of service under the considered attack is not necessarily degraded. Moreover, the quality of service can increase up to the moment of the sensor set crashes. We argue that this is a distinguishing type of attack. Hence, the application of a traditional defense mechanism against this threat is not always possible. Therefore, effective methods should be developed to counter the threat. We first discuss the feasibility of rash depletion of battery power. Next, we propose a model for evaluation of energy consumption when under attack. Finally, a technique to counter the attack is discussed.
A Non-Destructive and Direction-Insensitive Method Using a Strain Sensor and Two Single Axis Angle Sensors for Evaluating Corn Stalk Lodging Resistance
Authors: Guo Qingqian , Chen Ruipeng , Sun Xiaoquan , Jiang Min , Sun Haifeng , Wang Shun , Ma Liuzheng , Yang Yatao , Hu Jiandong
Published: June 2018

Corn stalk lodging is caused by different factors, including severe wind storms, stalk cannibalization, and stalk rots, and it leads to yield loss. Determining how to rapidly evaluate corn lodging resistance will assist scientists in the field of crop breeding to understand the contributing factors in managing the moisture, chemical fertilizer, and weather conditions for corn growing. This study proposes a non-destructive and direction-insensitive method, using a strain sensor and two single axis angle sensors to measure the corn stalk lodging resistance in the field. An equivalent force whose direction is perpendicular to the stalk is utilized to evaluate the corn lodging properties when a pull force is applied on the corn stalk. A novel measurement device is designed to obtain the equivalent force with the coefficient of variation (CV) of 4.85%. Five corn varieties with two different planting densities are arranged to conduct the experiment using the novel measurement device. The experimental results show that the maximum equivalent force could reach up to 44 N. A strong relationship with the square of the correlation coefficient of 0.88 was obtained between the maximum equivalent forces and the corn field’s stalk lodging rates. Moreover, the stalk lodging angles corresponding to the different pull forces over a measurement time of 20 s shift monotonically along the equivalent forces. Thus, the non-destructive and direction-insensitive method is an excellent tool for rapid analysis of stalk lodging resistance in corn, providing critical information on in-situ lodging dynamics.
Coupling of PZT Thin Films with Bimetallic Strip Heat Engines for Thermal Energy Harvesting
Authors: Boughaleb Jihane , Arnaud Arthur , Guiffard Benoit , Guyomar Daniel , Seveno Raynald , Monfray Stéphane , Skotnicki Thomas , Cottinet Pierre-Jean
Published: June 2018

A thermal energy harvester based on a double transduction mechanism and which converts thermal energy into electrical energy by means of piezoelectric membranes and bimetals, has previously been developed and widely presented in the literature In such a device, the thermo-mechanical conversion is ensured by a bimetal whereas the electro-mechanical conversion is generated by a piezoelectric ceramic. However, it has been shown that only 19% of the mechanical energy delivered by the bimetal during its snap is converted into electrical energy. To extract more energy from the bimetallic strip and to increase the transduction efficiency, a new way to couple piezoelectric materials with bimetals has thus been explored through direct deposition of piezoelectric layers on bimetals. This paper consequently presents an alternative way to harvest heat, based on piezoelectric bimetallic strip heat engines and presents a proof of concept of such a system. In this light, different PZT (Lead zirconate titanate) thin films were synthesized directly on aluminium foils and were attached to the bimetals using conductive epoxy. The fabrication process of each sample is presented herein as well as the experimental tests carried out on the devices. Throughout this study, different thicknesses of the piezoelectric layers and substrates were tested to determine the most powerful configuration. Finally, the study also gives some guidelines for future improvements of piezoelectric bimetals.
Accounting for Demography and Preferences: New Estimates of Residential Segregation with Minimum Segregation Measures
Authors: Timberlake Jeffrey M.
Published: June 2018

The index of dissimilarity (D) has historically been and continues to be a widely used quantitative measure of residential segregation. Conventional interpretations of D imply that normatively desirable residential patterns occur when ethnoracial compositions of lower-order geographic units (such as neighborhoods) match those of higher-order units (such as metropolitan areas). However, it is likely that average preferences for same-group contact in neighborhoods sometimes exceed group population shares in metropolitan areas. In such situations, there is mathematical tension between the capacity for group preferences for co-ethnic neighbors to be satisfied and the degree of residential segregation. In this article, I quantify this tension by calculating DΔ, or the difference between D and the minimum segregation measure D*, which returns the lower bound on segregation for a given average in-group preference level and ethnoracial share. Positive scores on DΔ indicate that a metropolitan area is more segregated than necessary to satisfy average group preferences, while negative scores indicate that observed residential patterns do not satisfy such preferences. I use data from the 2010 decennial census and 2006–2010 American Community Survey to analyze the associations between predictors of residential segregation and DΔ.
Mapping Satellite Inherent Optical Properties Index in Coastal Waters of the Yucatán Peninsula (Mexico)
Authors: Aguilar-Maldonado Jesús A. , Santamaría-Del-Ángel Eduardo , González-Silvera Adriana , Cervantes-Rosas Omar D. , Sebastiá-Frasquet María-Teresa
Published: June 2018

The Yucatán Peninsula hosts worldwide-known tourism destinations that concentrate most of the Mexico tourism activity. In this region, tourism has exponentially increased over the last years, including wildlife oriented tourism. Rapid tourism development, involving the consequent construction of hotels and tourist commodities, is associated with domestic sewage discharges from septic tanks. In this karstic environment, submarine groundwater discharges are very important and highly vulnerable to anthropogenic pollution. Nutrient loadings are linked to harmful algal blooms, which are an issue of concern to local and federal authorities due to their recurrence and socioeconomic and human health costs. In this study, we used satellite products from MODIS (Moderate Resolution Imaging Spectroradiometer) to calculate and map the satellite Inherent Optical Properties (IOP) Index. We worked with different scenarios considering both holiday and hydrological seasons. Our results showed that the satellite IOP Index allows one to build baseline information in a sustainable mid-term or long-term basis which is key for ecosystem-based management.
Evaluating Consistency in Environmental Policy Mixes through Policy, Stakeholder, and Contextual Interactions
Authors: Lieu Jenny , Spyridaki Niki Artemis , Alvarez-Tinoco Rocio , Van der Gaast Wytze , Tuerk Andreas , Van Vliet Oscar
Published: June 2018

This paper introduces a method to analyse and explore consistency within policy mixes in order to support the policymaking cycle and applies it to energy and climate change policies in the United Kingdom (UK) biofuels policy context. The first part of the paper introduces a multi-level method to evaluate consistency within policy mixes implemented over a period of time. The first level explores consistency across policy design features in policy mixes. The second level evaluates how stakeholders, and their interactions with policy instruments and each other, can impact consistency within a given context. These interactions influence the implementation of policies and can lead to unintended outcomes that fail to meet the overarching goals. In the second part of the paper, we apply our method to the UK biofuels policy mix, to explore a sector that cuts across the policy areas of transportation, energy, land-use, air, and climate change. Our analysis demonstrates how, by overlooking complex interactions in the design and implementation of policies in the biofuels sector, policy mixes have conflicted with the development of a potential low-carbon technology.
Diffusion of Corporate Philanthropy in Social and Political Network Environments: Evidence from China
Authors: Wu Wenqing , Yu Kexin , Chu Chien-Chi , Zhou Jie , Xu Hong , Tsai Sang-Bing
Published: June 2018

Based on the strong influence social networks have on managerial decision-making, as an important aspect of the strategic decision of the company, it is necessary to study how corporate social responsibility (CSR) actions could be affected by social networks. An analysis of 1725 Chinese listed firms and 40,484 executives from 2010 to 2014 showed that corporate philanthropy behavior will diffuse in social networks; more concretely, the higher the degree of social network centrality, the higher the enterprise’s donation level. Furthermore, the results also show that the role of social network centrality on corporate donation levels can be moderated by political connections. This study offers empirical evidence for developing a theoretical framework of CSR interaction and communication relevant to social networks, and offers insights into corporate philanthropy behavior based on social networks.
Writing a Recipe for Teaching Sustainable Food Systems: Lessons from Three University Courses
Authors: Brekken Christy Anderson , Peterson Hikaru Hanawa , King Robert P. , Conner David
Published: June 2018

The sustainability of the food system is at the forefront of academic and policy discussions as we face the challenge of providing food security to a growing population amidst environmental uncertainty and depletion, social disruptions, and structural economic shocks and stresses. Crafting a sustainable and resilient food system requires us to go beyond disciplinary boundaries and broaden critical and creative thinking skills. Recent literature calls for examples of pedagogical transformations from food systems courses to identify successful practices and potential challenges. We offer a recipe for what to teach by framing systems thinking concepts, then discuss how to teach it with five learning activities: deductive case studies, experiential learning, reflective narrative learning, system dynamics simulations and scenarios, and inductive/open-ended case studies, implemented with collaborative group learning, inter/trans-disciplinarity, and instructor-modeled co-learning. Each learning activity is animated with concrete examples from our courses at Oregon State University, University of Minnesota, and University of Vermont, USA. We discuss opportunities and challenges implementing these strategies in light of student, instructor, and institutional expectations and constraints. But the challenge is worth the effort, because food system transformation requires active learners and systemic thinkers as engaged citizens, food system advocates, entrepreneurs, and policy makers.
Engineering of Botulinum Neurotoxins for Biomedical Applications
Authors: Webb Robert P.
Published: June 2018

Botulinum neurotoxins (BoNTs) have been used as therapeutic agents in the clinical treatment of a wide array of neuromuscular and autonomic neuronal transmission disorders. These toxins contain three functional domains that mediate highly specific neuronal cell binding, internalization and cytosolic delivery of proteolytic enzymes that cleave proteins integral to the exocytosis of neurotransmitters. The exceptional cellular specificity, potency and persistence within the neuron that make BoNTs such effective toxins, also make them attractive models for derivatives that have modified properties that could potentially expand their therapeutic repertoire. Advances in molecular biology techniques and rapid DNA synthesis have allowed a wide variety of novel BoNTs with alternative functions to be assessed as potential new classes of therapeutic drugs. This review examines how the BoNTs have been engineered in an effort to produce new classes of therapeutic molecules to address a wide array of disorders.
Integrating Field Experiments with Modeling to Evaluate the Freshwater Availability at Ungauged Sites: A Case Study of Pingtan Island (China)
Authors: Liu Xiaocong , Wang Zhonggen , Tang Yin , Wu Zehua , Guo Yuhan , Cheng Yashan
Published: June 2018

Predictions in ungauged basins (PUB) has been always a focus of hydrological research. The problem presented by ungauged basins is how to reasonably estimate water resource availability. To solve the issues of data scale, this study combines field experiments and hydrological models to estimate freshwater availability in a typical ungauged sea island located in southeastern China. The free parameters in the hydrological model were derived from the point-scale rainfall-runoff experiments rather than calibration using river discharge observations. The rainfall-runoff experiments were performed on six sites covering 11 land cover types. Model validation at a sub-catchment showed that the combined method could successfully reproduce monthly streamflow, with a Nash–Sutcliffe Efficiency of 0.82, correlation coefficient of 0.85, and flow volume error of 6.5%. The simulation results indicate high heterogeneity and distinct seasonal dynamics in freshwater availability across the entire island. This pioneering PUB study for Chinese islands could provide reference for planning and management of freshwater in a water shortage area.
Academic Activism in Tourism Studies: Critical Narratives from Four Researchers
Authors: Hales Rob , Dredge Dianne , Higgins-Desbiolles Freya , Jamal Tazim
Published: June 2018

A climate of neoliberalism challenges the work of scholars whose research focuses on societal well-being through embedded community research and critical analysis of public policy, planning, and industry practices, what we call academic activism. This article draws on the autoethnographic insights and critical narratives of four tourism scholars to describe and analyze in a systematic manner the experiences of these researchers each engaged in what they consider to be academic activism. Our aim is to bring into focus and raise as matters of concern the future of tourism research in the neoliberal university and the need for greater critical and reflexive engagement by researchers in their positionality and agency. Although the contexts in which we work and our experiences differ greatly, the article identifies common themes, challenges, and opportunities within our approaches to research and action. Four emergent themes arose through the narrative analysis that helped to structure insights and findings: experiential journeys that shaped our current academic positionality and philosophical approaches to research and practice; a preference for embedded situated methodologies; a reflexive understanding of our political positioning; and a critical situated approach to understanding the external influences upon our research and strivings to contribute to the public good. The article raises challenging questions on the meaning of tourism research and the "public good" in the neoliberal university, and what being an academic activist entails in this context.
IMPACT OF HUMAN CAPITAL DEVELOPMENT ON PRODUCTIVITY GROWTH IN EU MEMBER STATES
Authors: Mačiulytė-Šniukienė Alma , Matuzevičiūtė Kristina
Published: June 2018

In this research, we investigate the impact of human capital on labour productivity in European Union member states using panel data analysis. Results of the paper are estimated using the Pooled ordinary least squares (OLS) and Fixed effects model (FEM). The results show that human capital is positively significant in improving the growth of labour productivity in the EU. Our estimates also suggest that the impact occurs after three times lags in case of education expenditure.
The Impact of Environment on the Stellar Mass–Halo Mass Relation
Authors: Golden-Marx Jesse B. , Miller Christopher J.
Published: June 2018

A large variance exists in the amplitude of the stellar mass–halo mass (SMHM) relation for group- and cluster-size halos. Using a sample of 254 clusters, we show that the magnitude gap between the brightest central galaxy (BCG) and its second or fourth brightest neighbor accounts for a significant portion of this variance. We find that at fixed halo mass, galaxy clusters with a larger magnitude gap have a higher BCG stellar mass. This relationship is also observed in semi-analytic representations of low-redshift galaxy clusters in simulations. This SMHM–magnitude gap stratification likely results from BCG growth via hierarchical mergers and may link the assembly of the halo with the growth of the BCG. Using a Bayesian model, we quantify the importance of the magnitude gap in the SMHM relation using a multiplicative stretch factor, which we find to be significantly non-zero. The inclusion of the magnitude gap in the SMHM relation results in a large reduction in the inferred intrinsic scatter in the BCG stellar mass at fixed halo mass. We discuss the ramifications of this result in the context of galaxy formation models of centrals in group- and cluster-size halos.
Upregulation of Twist2 in Non-Muscle Invasive Urothelial Carcinoma of the Bladder Correlate with Response to Treatment and Progression
Authors: Wishahi Mohamed , Khalil Heba , Badawy Mohamed H. , Elkholy Amr , Eseily Khaled , Anis Shady , Eldahshan Samir , Kamel Noura , Romeih Mahmoud
Published: June 2018

BACKGROUND: Twist2 is a transcription factor and an epithelial-to-mesenchymal transition that plays an important role in cell polarity, cell adhesion, and has a role in tumour invasion and metastases.AIM: In this study, we examined the expression of Twist2 in non-muscle invasive bladder carcinoma (NMIBC) and correlated the expression with response to treatment and tumour progression.METHODS: Data of 305 patients with NMIBC of Ta, T1 were retrieved from hospitals archives. Twist2 expression was examined in tissue samples by immunohistochemistry at initial diagnosis and final follow-up, normal control was 10 normal urothelium, 10 patients with muscle-invasive bladder cancer (MIBC) were a positive control. Treatment of NMIBC was implemented according to the European Association of Urology guidelines on NMIBC. The descriptive statistical analysis included means, standard deviation, p-value; Univariate and multivariate Cox regression analyses.RESULTS: Twist2 expression score was identified as negative, low (1-15%); medium (15-40%); and high (40-100%). Patients who had low or low medium scores at the initial diagnosis had a good response and a favourable prognosis. Expression of a high score of Twist2 in patients having high-grade T1 tumours showed non-responsiveness to repeated courses of intravesical bacillus Calmette Guerin (BCG) therapy and was upstaged to MIBC.CONCLUSION: Twist2 expression in tissue samples of NMIBC would indicate the tumour response to therapy, upgrading and upstaging in the follow up after intravesical BCG therapy.
Liver Protective Effects of Renin-Angiotensin System Inhibition Have No Survival Benefits in Hepatocellular Carcinoma Induced By Repetitive Administration of Diethylnitrosamine in Mice
Authors: Saber Sameh , Mahmoud Amr , Helal Noha , El-Ahwany Eman , Abdelghany Rasha
Published: June 2018

BACKGROUND: Preclinical studies have demonstrated that renin-angiotensin system (RAS) signalling has strong tumour-promoting effects and RAS inhibition was associated with improvement in the overall survival in some cancer types including hepatocellular carcinoma (HCC).OBJECTIVE: We aimed to investigate the effect of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin-II-receptor blockers (ARBs) on the survival of mice with diethylnitrosamine (DEN) induced HCC.METHODS: HCC was induced by weekly i.p. administration of DEN. Mice were treated with sorafenib (SO) (30 mg/kg), perindopril (PE) (1 mg/kg), fosinopril (FO) (2 mg/kg), losartan (LO) (10 mg/kg), PE (1 mg/kg) + SO (30 mg/kg), FO (2 mg/kg) + SO (30 mg/kg), or LO (10 mg/kg) + SO (30 mg/kg). Survival analysis was done using the Kaplan-Meier method, and the log-rank test was used for assessing the significance of difference between groups.RESULTS: The administration of PE, FO and LO as monotherapy or as combined with SO resulted in marked improvement in the liver histologic picture with no impact on overall survival of mice.CONCLUSION: Interfering the RAS either through the inhibition of ACE or the blockade of angiotensin II type 1 (AT1) receptors has similar effects on the liver of DEN-induced HCC mice and is not associated with longer survival due to detrimental effects of DEN on other organs. Hence, repetitive administration of DEN in such models of HCC is not suitable for mortality assessment studies.
Obstetric Outcome in Pregnant Patients with Low Level of Pregnancy-Associated Plasma Protein A in First Trimester
Authors: Livrinova Vesna , Petrov Igor , Samardziski Igor , Jovanovska Viktorija , Simeonova-Krstevska Slagjana , Todorovska Irena , Atanasova-Boshku Aleksandra , Gjorgjievska Milena
Published: June 2018

BACKGROUND: Pregnancy-associated plasma protein A (PAPP-A), is a protease which releases Insulin-like growth factor. The role of this factor is stimulation of cell mitosis, differentiation and trophoblastic invasion of deciduas. Identification of patients with low PAPP-A (under 0.4 MoM in the first trimester has an influence on birth weight, attenuation of fetal growth, preeclampsia, birth and fetal demise.AIM: The main issue in the study is evaluating an influence of PAPP-A, calculated in the first trimester on the unfavourable outcome of pregnancy.MATERIAL AND METHODS: Seventy pregnant women with singleton pregnancy underwent first-trimester biochemical screening. The target group were women with PAPP-A below 0.4 MoM, and in control group, PAPP-A were оver 0.4 MoM. There was an assessment of the influence on the mode of delivery, gestational week, the presence of intrauterine growth restriction, preeclampsia, temporary birth, intrauterine fetal demise and newborn condition.RESULTS: In target group, consisted of 35 patients, 16 were delivered at term. From 28 to 37 g.w.- were 7 patient, 22-28 g.w.- 4 and 8 patients were under the 22 g.w (all with fetal demise) there were 19 pretemporary deliveries - 9 with Cesarean Section (SC). In the target group: 5 newborn wеre with IUGR, 6 women had preeclampsia, 1 had placental abruption. In control group were 35 patients: 28 delivered at term, 9 with SC, 26 vaginal deliveries; with IUGR were 4 newborns. Two newborns were hypertrophic.CONCLUSION: There is a significant difference in unfavourable outcome in the cases with PAPP-A under 0.4 Mom, particular in the group, with a PAPP-A value under 0.2 MoM. The patients delivered with SC with the main indications in utero hypoxia, growth restriction and elevated blood pressure had PAPP-A between 0.3-0.4 MoM. The patients with intrauterine fetal death and placental abruption in the most of the cases have PAPP-A value under 0.2 MoM. There is a need to be aware in these pregnancies to achieve the preventions of adverse outcome, to decrease perinatal morbidity and mortality.
Cave-dwelling pholcid spiders (Araneae, Pholcidae): a review
Authors: Huber Bernhard A.
Published: June 2018

Pholcidae are ubiquitous spiders in tropical and subtropical caves around the globe, yet very little is known about cave-dwelling pholcids beyond what is provided in taxonomic descriptions and faunistic papers. This paper provides a review based on a literature survey and unpublished information, while pointing out potential biases and promising future projects. A total of 473 native (i.e. non-introduced) species of Pholcidae have been collected in about 1000 caves. The large majority of cave-dwelling pholcids are not troglomorphic; a list of 86 troglomorphic species is provided, including 21 eyeless species and 21 species with strongly reduced eyes. Most troglomorphic pholcids are representatives of only two genera:AnopsicusChamberlin & Ivie, 1938 andMetagoniaSimon, 1893. Mexico is by far the richest country in terms of troglomorphic pholcids, followed by several islands and mainland SE Asia. The apparent dominance of Mexico may partly be due to collectors’ and taxonomists’ biases. Most caves harbor only one pholcid species, but 91 caves harbor two and more species (up to five species). Most troglomorphic pholcids belong to two subfamilies (Modisiminae, Pholcinae), very few belong to Smeringopinae and Arteminae, none to Ninetinae. This is in agreement with the recent finding that within Pholcidae, microhabitat changes in general are concentrated in Modisiminae and Pholcinae.
Two new species of the genus Dryopomorphus Hinton, 1936 from China (Coleoptera, Elmidae)
Authors: Bian Dongju , Dong Xue , Peng Yunfei
Published: June 2018

Two new species of the genusDryopomorphusHinton, 1936 are described from China:Dryopomorphusheinerisp. n.andD.ruiliensissp. n.Habitus photographs and detailed line drawings of the male genitalia are provided.