bluuebunny/crossref_metadata_2025 huggingface dataset:
A qualitative study on stress, coping strategies and feasibility of music intervention among women with cancer receiving chemotherapy during COVID-19 pandemic in Vietnam
Authors: Nguyen Khanh T. , Vu Nhung T. H. , Tran Mai T. T. , Chan Carmen W. H.
Published: January 2023

Breast and gynaecological cancer (BGC) patients receiving chemotherapy may experience high levels of stress during the COVID-19 pandemic. Music interventions may be effective in lowering their stress levels. This study explored stressors, coping strategies, and the feasibility of music interventions among BGC patients in Vietnam. An exploratory qualitative study with individual face-to-face semi-structured interviews was conducted. A convenience sample of BGC patients receiving chemotherapy was recruited from the oncology centre of a public hospital in Vietnam. Twenty patients were interviewed with open-ended questions developed based on the transactional model of stress and coping to explore stress-causing factors and coping strategies and based on guidelines for music therapy practice to explore their music preferences and perceptions. Field notes and interview transcripts were analysed following the qualitative content analysis approach. Two stressor themes were identified: undesirable experiences during treatment and patients’ inability to fulfil their own roles and responsibilities. Our findings revealed a new coping strategy—self-realisation of responsibilities towards the family—that is not listed in the transactional model of stress and coping. Future psychological interventions for stress management among BGC patients should focus on raising the patients’ awareness of their values and responsibilities towards their families. Three categories of preferred music genres for stress reduction were identified: religious, softly melodic, and revolutionary music. The patients were aware of the positive effects of music and had different musical preferences. This study also explored the acceptance of music interventions and facilitators and barriers to implementing them among BGC patients in Vietnam. The findings suggest that before implementing music interventions, the musical preferences, religions, and beliefs of each individual should be considered to achieve desirable results. Music interventions for BGC patients receiving chemotherapy in Vietnam are feasible. Further intervention studies are needed to evaluate their effectiveness.
CT-radiomics and clinical risk scores for response and overall survival prognostication in TACE HCC patients
Authors: Bernatz Simon , Elenberger Oleg , Ackermann Jörg , Lenga Lukas , Martin Simon S. , Scholtz Jan-Erik , Koch Vitali , Grünewald Leon D. , Herrmann Yannis , Kinzler Maximilian N. , Stehle Angelika , Koch Ina , Zeuzem Stefan , Bankov Katrin , Doering Claudia , Reis Henning , Flinner Nadine , Schulze Falko , Wild Peter J. , Hammerstingl Renate , Eichler Katrin , Gruber-Rouh Tatjana , Vogl Thomas J. , dos Santos Daniel Pinto , Mahmoudi Scherwin
Published: January 2023

We aimed to identify hepatocellular carcinoma (HCC) patients who will respond to repetitive transarterial chemoembolization (TACE) to improve the treatment algorithm. Retrospectively, 61 patients (mean age, 65.3 years ± 10.0 [SD]; 49 men) with 94 HCC mRECIST target-lesions who had three consecutive TACE between 01/2012 and 01/2020 were included. Robust and non-redundant radiomics features were extracted from the 24 h post-embolization CT. Five different clinical TACE-scores were assessed. Seven different feature selection methods and machine learning models were used. Radiomics, clinical and combined models were built to predict response to TACE on a lesion-wise and patient-wise level as well as its impact on overall-survival prognostication. 29 target-lesions of 19 patients were evaluated in the test set. Response rates were 37.9% (11/29) on the lesion-level and 42.1% (8/19) on the patient-level. Radiomics top lesion-wise response prognostications was AUC 0.55–0.67. Clinical scores revealed top AUCs of 0.65–0.69. The best working model combined the radiomic feature LargeDependenceHighGrayLevelEmphasis and the clinical score mHAP_II_score_group with AUC = 0.70, accuracy = 0.72. We transferred this model on a patient-level to achieve AUC = 0.62, CI = 0.41–0.83. The two radiomics-clinical features revealed overall-survival prognostication of C-index = 0.67. In conclusion, a random forest model using the radiomic feature LargeDependenceHighGrayLevelEmphasis and the clinical mHAP-II-score-group seems promising for TACE response prognostication.
Photo-plasmonic effect as the hot electron generation mechanism
Authors: Akbari-Moghanjoughi M.
Published: January 2023

Based on the effective Schrödinger–Poisson model a new physical mechanism for resonant hot-electron generation at irradiated half-space metal–vacuum interface of electron gas with arbitrary degree of degeneracy is proposed. The energy dispersion of undamped plasmons in the coupled Hermitian Schrödinger–Poisson system reveals an exceptional point coinciding the minimum energy of plasmon conduction band. Existence of such exceptional behavior is a well-know character of damped oscillation which in this case refers to resonant wave–particle interactions analogous to the collisionless Landau damping effect. The damped Schrödinger–Poisson system is used to model the collective electron tunneling into the vacuum. The damped plasmon energy dispersion is shown to have a full-featured exceptional point structure with variety of interesting technological applications. In the band gap of the damped collective excitation,depending on the tunneling parameter value, there is a resonant energy orbital for which the wave-like growing of collective excitations cancels the damping of the single electron tunneling wavefunction. This important feature is solely due to dual-tone wave-particle oscillations, characteristics of the collective excitations in the quantum electron system leading to a resonant photo-plasmonic effect, as a collective analog of the well-known photo-electric effect. The few nanometer wavelengths high-energy collective photo-electrons emanating from the metallic surfaces can lead to a much higher efficiency of plasmonic solar cell devices, as compared to their semiconductor counterpart of electron–hole excitations at the Fermi energy level. The photo-plasmonic effect may also be used to study the quantum electron tunneling and electron spill-out at metallic surfaces. Current findings may help to design more efficient spasers by using the feature-rich plasmonic exceptional point structure.
Auxin supplementation under nitrogen limitation enhanced oleic acid and MUFA content in Eustigmatos calaminaris biomass with potential for biodiesel production
Authors: Krzemińska Izabela , Szymańska Marlena , Ciempiel Wioleta , Piasecka Agata
Published: January 2023

Due to their lipid accumulation potential, microalgae are widely studied in terms of their use in the production of biodiesel. The present study was focused on determination of changes in the biomass production, biochemical composition, accumulation and distribution of fatty acids in neutral lipids, glycolipids, phospholipids and biodiesel properties of soil microalga Eustigmatos calaminaris in response to various levels of nitrogen stress and indole-3-acetic acid supplementation. The highest growth rate, the highest lipid content and daily lipid productivity were noted at the nitrogen limitation up to 25% with IAA supplementation. The increase in NL was associated with nutrient stress. An increase in the level of GL and PL were recorded upon the reduction of the nitrogen content (25% N) and the addition of IAA. The gas chromatography/mass spectrometry analysis demonstrated that C16:0, C16:1, and C18:1 were the main fatty acids in E. calaminaris lipids. As shown by the lipidomic analysis, the IAA supplementation in the nitrogen limitation variants enhanced the content of TAGs in C18:1 and monounsaturated fatty acids. The current findings indicated a potential strategy to improve the fatty acid profile in neutral lipids and high potential of E. calaminaris for biodiesel applications.
Synthesis of superhydrophobic coatings based on silica nanostructure modified with organosilane compounds by sol–gel method for glass surfaces
Authors: Ghodrati Mohammad , Mousavi-Kamazani Mehdi , Bahrami Zohreh
Published: January 2023

In the present study, the superhydrophobic coating was synthesized by spherical silica nanostructures modified with organosilane compounds for glass surfaces. To optimize the conditions in terms of cost-effectiveness and create a super-hydrophobic coating with a high contact angle, the response surface method of the central composite design (CCD) model was performed for the StÖber method, and the contact angle was defined as the response surface for the model. Tetraethoxysilane (TEOS) was used as a precursor and poly(dimethylsiloxane) (PDMS) was used to modify the surface of a spherical silica nanostructure synthesized by a one-step sol–gel method using a base catalyst. The accuracy of the research was checked by the contact angle measurement test and an angle of 162° was obtained. XRD, FT-IR, EDS, SEM, DLS, and AFM analyzes were performed to investigate the synthesis of silica nanostructure. Chemical resistance was performed in acidic, neutral, and alkaline environments and the contact angles were 127°, 134°, and 90°, respectively, which indicates that the coating created on the surface glass has good chemical resistance in acidic and neutral environments.
Modeling and affinity maturation of an anti-CD20 nanobody: a comprehensive in-silico investigation
Authors: Poustforoosh Alireza , Faramarz Sanaz , Negahdaripour Manica , Hashemipour Hassan
Published: January 2023

B-cell Non-Hodgkin lymphomas are the malignancies of lymphocytes. CD20 is a membrane protein, which is highly expressed on the cell surface of the B-cells in NHL. Treatments using monoclonal antibodies (mAbs) have resulted in failure in some cases. Nanobodies (NBs), single-domain antibodies with low molecular weights and a high specificity in antigen recognition, could be practical alternatives for traditional mAbs with superior characteristics. To design an optimized NB as a candidate CD20 inhibitor with raised binding affinity to CD20, the structure of anti-CD20 NB was optimized to selectively target CD20. The 3D structure of the NB was constructed based on the optimal templates (6C5W and 5JQH), and the key residues were determined by applying a molecular docking study. After identifying the key residues, some mutations were introduced using a rational protocol to improve the binding affinity of the NB to CD20. The rational mutations were conducted using the experimental design (Taguchi method). Six residues (Ser27, Thr28, Phe29, Ile31, Asp99, and Asn100) were selected as the key residues, and five residues were targeted for rational mutation (Trp, Phe, His, Asp, and Tyr). Based on the mutations suggested by the experimental design, two optimized NB structures were constructed. NB2 showed a remarkable binding affinity to CD20 in docking studies with a binding energy of − 853 kcal/mol. The optimized NB was further evaluated using molecular dynamics simulation. The results revealed that CDR1 (complementarity determining regions1) and CDR3 are essential loops for recognizing the antigen. NB2 could be considered as a potential inhibitor of CD20, though experimental evaluations are needed to confirm it.
Antibody-drug conjugates in lung cancer: dawn of a new era?
Authors: Coleman Niamh , Yap Timothy A. , Heymach John V. , Meric-Bernstam Funda , Le Xiuning
Published: January 2023

Antibody-drug conjugates (ADCs) are one of fastest growing classes of oncology drugs in modern drug development. By harnessing the powers of both cytotoxic chemotherapy and targeted therapy, ADCs are unique in offering the potential to deliver highly potent cytotoxic agents to cancer cells which express a pre-defined cell surface target. In lung cancer, the treatment paradigm has shifted dramatically in recent years, and now ADCs are now joining the list as potential options for lung cancer patients. Since 2020, the first ADC for NSCLC patients has been FDA-approved (trastuzumab deruxtecan) and two ADCs have been granted FDA Breakthrough Therapy Designation, currently under evaluation (patritumab deruxtecan, telisotuzumab vedotin). Furthermore, several early-phase trials are assessing various novel ADCs, either as monotherapy or in combinations with advanced lung cancer, and more selective and potent ADCs are expected to become therapeutic options in clinic soon. In this review, we discuss the structure and mechanism of action of ADCs, including insights from pre-clinical work; we summarize the ADCs’ recent progress in lung cancer, describe toxicity profiles of ADCs, and explore strategies designed to enhance ADC potency and overcome resistance. In addition, we discuss novel ADC strategies of interest in lung cancer, including non-cytotoxic payloads, such as immunomodulatory and anti-apoptotic agents.
Effectiveness of gamified team competition as mHealth intervention for medical interns: a cluster micro-randomized trial
Authors: Wang Jitao , Fang Yu , Frank Elena , Walton Maureen A. , Burmeister Margit , Tewari Ambuj , Dempsey Walter , NeCamp Timothy , Sen Srijan , Wu Zhenke
Published: January 2023

Gamification, the application of gaming elements to increase enjoyment and engagement, has the potential to improve the effectiveness of digital health interventions, while the effectiveness of competition gamification components remains poorly understood on residency. To address this gap, we evaluate the effect of smartphone-based gamified team competition intervention on daily step count and sleep duration via a micro-randomized trial on medical interns. Our aim is to assess potential improvements in the factors (namely step count and sleep) that may help interns cope with stress and improve well-being. In 1779 interns, team competition intervention significantly increases the mean daily step count by 105.8 steps (SE 35.8, p = 0.03) relative to the no competition arm, while does not significantly affect the mean daily sleep minutes (p = 0.76). Moderator analyses indicate that the causal effects of competition on daily step count and sleep minutes decreased by 14.5 steps (SE 10.2, p = 0.16) and 1.9 minutes (SE 0.6, p = 0.003) for each additional week-in-study, respectively. Intra-institutional competition negatively moderates the causal effect of competition upon daily step count by −90.3 steps (SE 86.5, p = 0.30). Our results show that gamified team competition delivered via mobile app significantly increases daily physical activity which suggests that team competition can function as a mobile health intervention tool to increase short-term physical activity levels for medical interns. Future improvements in strategies of forming competition opponents and introducing occasional competition breaks may improve the overall effectiveness.
DNA uptake from a laboratory environment drives unexpected adaptation of a thermophile to a minor medium component
Authors: Zeldes Benjamin , Poehlein Anja , Jain Surbhi , Baum Christoph , Daniel Rolf , Müller Volker , Basen Mirko
Published: January 2023

DNA uptake is widespread among microorganisms and considered a strategy for rapid adaptation to new conditions. While both DNA uptake and adaptation are referred to in the context of natural environments, they are often studied in laboratories under defined conditions. For example, a strain of the thermophile Thermoanaerobacter kivui had been adapted to growth on high concentrations of carbon monoxide (CO). Unusual phenotypes of the CO-adapted strain prompted us to examine it more closely, revealing a horizontal gene transfer (HGT) event from another thermophile, Thermoanaerobacter sp. strain X514, being cultured in the same laboratory. The transferred genes conferred on T. kivui the ability to utilize trehalose, a trace component of the yeast-extract added to the media during CO-adaptation. This same HGT event simultaneously deleted a native operon for thiamine biosynthesis, which likely explains why the CO-adapted strain grows poorly without added vitamins. Attempts to replicate this HGT by providing T. kivui with genomic DNA from Thermoanaerobacter sp. strain X514 revealed that it is easily reproducible in the lab. This subtle form of “genome contamination” is difficult to detect, since the genome remains predominantly T. kivui, and no living cells from the original contamination remain. Unexpected HGT between two microorganisms as well as simultaneous adaptation to several conditions may occur often and unrecognized in laboratory environments, requiring caution and careful monitoring of phenotype and genotype of microorganisms that are naturally-competent for DNA uptake.
A chiral sensing platform based on a multi-substituted ferrocene–cuprous ion complex for the discrimination of electroactive amino acid isomers
Authors: Wen Tai , Li Junyao , Cai Wenrong , Yang Baozhu , Kong Yong , Yin Zheng-Zhi
Published: January 2023

An electrochemical chiral sensing platform based on a multi-substituted ferrocene–Cu+ complex is constructed for the discrimination of electroactive amino acid isomers.
An inner filter effect-based fluorescent aptasensor for sensitive detection of kanamycin in complex samples using gold nanoparticles and graphene oxide quantum dots
Authors: Li Mengyan , Huang Ruoying , Liao Xiaofei , Zhou Zidan , Zou Li , Liu Bing
Published: January 2023

A label-free fluorescent aptasensor for kanamycin detection was developed based on the efficient IFE of AuNPs on GOQDs.
A metalloporphyrin and hydantoin functionalized nanozyme with synergistically enhanced bacterial inhibition
Authors: Li Yanhong , Wang Quanbo , Qu Xinyan , Zhang Qiang , Zhang Xiaomei
Published: January 2023

An elaborate design of multimodal antibacterial agents has been revealed to be a promising strategy to address bacterial resistance, originating from the abuse of antibiotics.
Endoplasmic reticulum-targeted NIR-II phototherapy combined with inflammatory vascular suppression elicits a synergistic effect against TNBC
Authors: Wan Guoyun , Chen Xuheng , Chen Jiayu , Gou Ruiling , Wang Haijiao , Liu Shuhao , Zhang Mingyang , Chen Hongli , Wang Dan , Zhang Qiqing
Published: January 2023

A multifunctional nanoplatform for the holistic treatment on TNBC by combining endoplasmic reticulum-targeted NIR-II phototherapy and inflammatory vascular suppression.
The additional nitrogen atom breaks the uranyl structure: a combined photoelectron spectroscopy and theoretical study of NUO2−
Authors: Hong Jing , Han Changcai , Fei Zejie , Tang Yuanyuan , Liu Yancheng , Xu Hong-Guang , Wang Mingqing , Liu Hongtao , Xiong Xiao-Gen , Dong Changwu
Published: January 2023

The photoelectron image and photoelectron spectrum of NUO2− at 310 nm and optimized geometries for different electronic states.
Direct analysis at temporal and molecular level of deactivating coke species formed on zeolite catalysts with diverse pore topologies
Authors: Hita Idoia , Mohamed Hend Omar , Attada Yerrayya , Zambrano Naydu , Zhang Wen , Ramírez Adrian , Castaño Pedro
Published: January 2023

The mechanistic understanding of coke formation on zeolites is elusive, and we have developed a method to directly analyze the coke species through high-res mass spectrometry.
Low volume expansion hierarchical porous sulfur-doped Fe2O3@C with high-rate capability for superior lithium storage
Authors: Chen Jiatao , Zhu Kongjun , Rao Yu , Liang Penghua , Zhang Jie , Zheng Hongjuan , Shi Feng , Yan Kang , Wang Jing , Liu Jinsong
Published: January 2023

Super fine Fe2O3 nanoparticles are confined inside the carbon shell and S-doping enables MOF-derived S0.15–Fe2O3@C nano-spindles to exhibit high-rate capability and low volume.
RE-doped (RE = La, Ce and Er) Ni2P porous nanostructures as promising electrocatalysts for hydrogen evolution reaction
Authors: Wang Qin , Liu Jinxing , Yan Xiaochen , Li Tong , Li Jian , Wang Yufei , Yan Long , Cao Longsheng
Published: January 2023

It was found that Er-doped Ni2P porous nanostructures displayed excellent HER performance.
Optimization of oxygen evolution activity by tuning e*g band broadening in nickel oxyhydroxide
Authors: Zhong Haoyin , Wang Xiaopeng , Sun Guangxin , Tang Yaxin , Tan Shengdong , He Qian , Zhang Jun , Xiong Ting , Diao Caozheng , Yu Zhigen , Xi Shibo , Lee Wee Siang Vincent , Xue Junmin
Published: January 2023

In Ni(OH)2, a greater extent of band (3d electron states with egsymmetry) broadening can facilitate electron transfer from the electrocatalyst to the external circuit, leading to higher OER catalytic performance.
Purple tea: chemical characterization and evaluation as inhibitor of pancreatic lipase and fat digestion in mice
Authors: da Silva Tamires Barlati Vieira , Dias Maria Inês , Pereira Carla , Mandim Filipa , Ivanov Marija , Soković Marina , Ferreira Isabel C. F. R. , Barros Lillian , Seixas Flávio Augusto Vicente , Bracht Adelar , Peralta Rosane Marina
Published: January 2023

Inhibition of triglyceride absorption by purple tea suggests antiobesity activity and is likely to occur by two different mechanisms.
Effect of gas temperature on composition concentration measurements by laser-induced breakdown spectroscopy
Authors: Zhu Zhifeng , Wang Xiaoyu , Wu Tengfei , Li Zhongshan , Gao Ercong , Gao Qiang , Li Bo
Published: January 2023

Laser-induced Breakdown Spectroscopy (LIBS) is widely applied to the quantitative measurement of gas composition concentrations.
Microneedle-based transdermal detection and sensing devices
Authors: Wang Junxia , Lu Ziyi , Cai Ruisi , Zheng Hanqi , Yu Jicheng , Zhang Yuqi , Gu Zhen
Published: January 2023

This review summarizes state-of-the-art microneedle-based detection and sensing systems, highlighting the objective significance, sensing principles, systematic construction, and validation models of these microneedles.
Producing natural-colored super-powerful antibacterial cotton with plasma-assisted fiber surface modification: a green and effective cotton process for medical and healthcare applications
Authors: Li Zhonghua , Zhang Yanyun , Xia Weibang , Tang Yijun , Li Qing
Published: January 2023

A green and effective cotton process from herbal plant of F. Artemisiae argyi as a source of natural dye and bio-agent.
Nanotechnology-based diagnostics and therapeutics in acute lymphoblastic leukemia: a systematic review of preclinical studies
Authors: Khademi Reyhane , Mohammadi Zahra , Khademi Rahele , Saghazadeh Amene , Rezaei Nima
Published: January 2023

Nanotechnology and ALL.
Comparison of carbon dots prepared from collagen peptides using conventional hydrothermal and microwave methods
Authors: Xu Chengzhi , Kang Jizhen , Zhao Yanqiu , Zhu Lian , Zhang Juntao , Wei Benmei , Wang Haibo
Published: January 2023

Differences between CDs prepared by microwave reaction and conventional hydrothermal methods were systematically compared to guide the optimization of the reaction parameters of biomass-derived CDs.
Fly ash electrodes fabricated by an acid-assisted subcritical water extraction method for supercapacitor applications
Authors: Lie Jenni , Shuwanto Hardy , Abdullah Hairus , Ismadji Suryadi , Warmadewanthi I. D. A. A. , Soetaredjo Felycia Edi
Published: January 2023

Fly ash waste was treated by acidic subcritical water extraction (SWE) treatment for producing supercapacitor materials.
Synthesis process and adsorption performance of temperature-sensitive ion-imprinted porous microspheres (ReO4−-TIIM) for the selective separation of ReO4−
Authors: Niu Fangfang , Xu Wan , Wu Gang , Lu Siyuan , Ou Xiaojian , Chen Zhenbin , Zhao Xinyu , Sun Yuan , Song Yuanjun , Zhang Peng
Published: January 2023

The adsorption–desorption process of imprinted microspheres is controlled by changing the temperature conditions of the external environment.
Theoretical determination of superior high-temperature thermoelectricity in an n-type doped 2H-ZrI2 monolayer
Authors: Wen Jia , Peng Jie , Zhang Bokai , Wang Zhi-Yong
Published: January 2023

A two-dimensional 2H-ZrI2 monolayer is identified as a high-performance n-type thermoelectric material in the high-temperature regime for its favorable thermal conductivity and ultrahigh power factor.
Impact of nanopillars on phonon dispersion and thermal conductivity of silicon membranes
Authors: Anufriev Roman , Ohori Daisuke , Wu Yunhui , Yanagisawa Ryoto , Jalabert Laurent , Samukawa Seiji , Nomura Masahiro
Published: January 2023

Silicon nanopillars are shown to produce local resonances in phonon dispersion but have negligible impact on the thermal conductivity of silicon membranes.
Super-adsorbent microspheres based on a triallyl isocyanurate–maleic anhydride copolymer for the removal of organic pollutants from water
Authors: Xu Can , Shu Hongyi , Chen Chuxuan , Qi Xi , Zhou Pengfei , Ma Yuhong , Zhao Changwen , Yang Wantai
Published: January 2023

Cationic nanoporous microspheres were designed for the removal of diclofenac sodium, and they showed a rapid adsorption rate (reached equilibrium within 30 min), a high equilibrium adsorption capacity (1421 mg g−1), and excellent recyclability.
Correction: Atomic-scale detection of individual lead clusters confined in Linde Type A zeolites
Authors: Fatermans Jarmo , Romolini Giacomo , Altantzis Thomas , Hofkens Johan , Roeffaers Maarten B. J. , Bals Sara , Van Aert Sandra
Published: January 2023

Correction for ‘Atomic-scale detection of individual lead clusters confined in linde type A zeolites’ by Jarmo Fatermans et al., Nanoscale, 2022, 14, 9323–9330, https://doi.org/10.1039/D2NR01819E.
Methylene blue sensitized photo Fenton-like reaction for rapid RAFT polymerization in aqueous solution
Authors: Fan Jiangtao , Li Cuiting , Guo Xie , Deng Yuanming
Published: January 2023

Rapid aqueous RAFT polymerization of acrylamides (DMA, NAM) with good oxygen tolerance initiated by ˙OH generated from methylene blue (MB) activated decomposition of H2O2under red light irradiation is presented.
Interface engineering and heterometal-doped FeOOH/Ga-Ni3S2nanosheet arrays for efficient electrocatalytic oxygen evolution
Authors: Wang Rui , Yang Yang , Xu Xiaocheng , Chen Sijie , Trukhanov Alex , Wang Ruiying , Shao Lianyi , Lu Xia , Pan Hui , Sun Zhipeng
Published: January 2023

The exploration of highly efficient and stable non-noble metal electrocatalysts for oxygen evolution reaction (OER) is a crucial challenge.
Cesium manganese halide perovskite-analogue nanocrystals with highly efficient energy conversion for flexible multifunctional fibers
Authors: Duan Xiuqiang , Nie Kun , Wang Xuyi , Cheng Chi-An , Zhou Ranran , Hu Ziyao , Yan Junbao , Mei Lefu , Ma Xiaoxue , Yao Songjun , Wang Luoxin , Wang Hua
Published: January 2023

Pb2+-doped Cs2Mn(Cl/Br)4·2H2O PA NCs exhibit excellent luminescence properties and stability, and can be used in fibers and other uses.
Coupling oxygen vacancy gradient distribution and flexoelectric effects for enhanced photovoltaic performance in bismuth ferrite films
Authors: Sun Zehao , Wei Jie , Li Yunpeng , Liu Zhiting , Xiahou Minchuan , Chen Guogang , Zhao Lin , Cheng Zhenxiang
Published: January 2023

Coupling oxygen vacancy gradient distribution and flexoelectricity for the enhancement of ferroelectric photovoltaic effects.
Insight into TLR4 receptor inhibitory activity via QSAR for the treatment of Mycoplasma pneumonia disease
Authors: Zhu Zemin , Rahman Ziaur , Aamir Muhammad , Shah Syed Zahid Ali , Hamid Sattar , Bilawal Akhunzada , Li Sihong , Ishfaq Muhammad
Published: January 2023

Mycoplasma pneumoniae (MP) is one of the most common pathogenic organisms causing upper and lower respiratory tract infections, lung injury, and even death in young children.
Catalytic ozonation of sulfamethoxazole using low-cost natural silicate ore supported Fe2O3: influencing factors, reaction mechanisms and degradation pathways
Authors: Luo Lisha , Sun Zhiyu , Chen Yuxi , Zhang Hui , Sun Yinkun , Lu Dongwei , Ma Jun
Published: January 2023

FeSO was prepared using an impregnation method, and showed remarkable ozonation catalytic activity for the degradation of sulfamethoxazole, which followed ˙OH production mechanism.
Chemical bonding and dynamic structural fluxionality of a boron-based Al2B8 binary cluster: the robustness of a doubly 6π/6σ aromatic [B8]2− molecular wheel
Authors: Yue Rong-Xin , Gao Shu-Juan , Han Peng-Fei , Zhai Hua-Jin
Published: January 2023

Boron-based Al2B8 cluster assumes a sandwich structure. The Al2 unit floats above and below a boron wheel, featuring intriguing dynamic fluxionality.
Circularly polarised luminescence from excimer emission of anthracene derivatives complexed with γ-cyclodextrin in the solid state
Authors: Kakimoto Yuna , Ikemura Ryoya , Imai Yoshitane , Tohnai Norimitsu , Yamazaki Shoko , Nakata Eiji , Takashima Hiroshi
Published: January 2023

The 9-substituted anthracene derivative forms a spatially restricted dimer in the cavity of γ-cyclodextrin and exhibits circularly polarised luminescence with gCPL = +1.3 × 10−3 in the solid state.
Remarkable solar thermochemical CO2 splitting performances based on Ce- and Al-doped SrMnO3 perovskites
Authors: Gao Ke , Liu Xianglei , Wang Qi , Jiang Zhixing , Tian Cheng , Sun Nan , Xuan Yimin
Published: January 2023

In the solar thermochemical CO2 splitting process, a remarkable CO yield (799.34 μmol g−1) at 1350/1100 °C is reported based on proposed Sr0.6Ce0.4Mn0.8Al0.2O3.
Continuous flow hydrogenolysis of 5-hydroxymethylfurfural into 2,5-dimethylfuran over alumina-supported nickel–iron alloy catalysts
Authors: Kalong Munsuree , Srifa Atthapon , Ratchahat Sakhon , Koo-amornpattana Wanida , Poo-arporn Yingyot , Limphirat Wanwisa , Khemthong Pongtanawat , Assabumrungrat Suttichai , Tomishige Keiichi , Kawi Sibudjing
Published: January 2023

Continuous hydrogenolysis of 5-hydroxymethylfurfural to 2,5-dimethylfuran is successfully developed and demonstrated using alumina-supported nickel–iron alloy catalysts with in situ observation of the structural transformation.
Modulation of double-network hydrogels via seeding calcium carbonate microparticles for the engineering of ultrasensitive wearable sensors
Authors: Zhang Xiaohui , Geng Huimin , Zhang Xunhui , Liu Yaqing , Hao Jingcheng , Cui Jiwei
Published: January 2023

Stretchable and tough double-network hydrogels mediated by CaCO3 microparticles can be used to monitor human motions and mild pain signals at the wound site.
Conducting gels for wearable bioelectronic devices
Authors: Inal Sahika
Published: January 2023

Sahika Inal discusses the development of conducting gels for wearable bioelectronic devices over the past couple of years and compiles some of the most recent and relevant research published in Journal of Materials Chemistry B in this Editor’s choice collection.
The unexpected mechanism of transformation from conventional room-temperature phosphorescence to TADF-type organic afterglow triggered by simple chemical modification
Authors: Wu Minjian , Li Jiuyang , Huang Ju , Wang Xuepu , Wang Guangming , Chen Xiuzheng , Li Xun , Chen Xuefeng , Ding Shuhui , Zhang Hefeng , Zhang Kaka
Published: January 2023

This study presents the mechanism of transformation of afterglow induced by specific chemical reactions. Consequently, highly efficient red TADF-type afterglow materials that counteract with the energy gap law have been achieved.
Manganese and selenium co-doped CeO2@Co3O4 porous core–shell nanospheres for enhanced oxygen evolution reactions
Authors: Huang Xianggang , Wang Xin , Zhang Mengling , Jiang Qilei , Qin Zheng , Liu Yingxin , Hou Yan , Cao Xueqin , Gu Hongwei
Published: January 2023

MnSe–CeO2@Co3O4 synthesised by a one-pot multi-step method, followed by calcination and selenization treatments, exhibits superior electrocatalytic activity and stability.
Correction: A butterfly shaped organic heterojunction photocatalyst for effective photocatalytic CO2 reduction
Authors: Hayat Asif , Sohail Muhammad , Taha T. A. , Alenad Asma M. , Irfan Ahmad , Shaishta Naghma , Hayat Ashiq , Mane Sunil Kumar Baburao , Khan Wasim Ullah
Published: January 2023

Correction for ‘A butterfly shaped organic heterojunction photocatalyst for effective photocatalytic CO2 reduction’ by Asif Hayat et al., CrystEngComm, 2021, 23, 4963–4974, https://doi.org/10.1039/D1CE00405K.
Impact of nanoparticles on amyloid β-induced Alzheimer’s disease, tuberculosis, leprosy and cancer: a systematic review
Authors: Chakraborty Ayon , Mohapatra Saswati Soumya , Barik Subhashree , Roy Ipsita , Gupta Bhavika , Biswas Ashis
Published: January 2023

Nanotechnology is an interdisciplinary domain of science, technology and engineering that deals with nano-sized materials/particles. Usually, the size of nanoparticles lies between 1 and 100 nm. Due to their small size and large surface area-to-volume ratio, nanoparticles exhibit high reactivity, greater stability and adsorption capacity. These important physicochemical properties attract scientific community to utilize them in biomedical field. Various types of nanoparticles (inorganic and organic) have broad applications in medical field ranging from imaging to gene therapy. These are also effective drug carriers. In recent times, nanoparticles are utilized to circumvent different treatment limitations. For example, the ability of nanoparticles to cross the blood−brain barrier and having a certain degree of specificity towards amyloid deposits makes themselves important candidates for the treatment of Alzheimer’s disease. Furthermore, nanotechnology has been used extensively to overcome several pertinent issues like drug-resistance phenomenon, side effects of conventional drugs and targeted drug delivery issue in leprosy, tuberculosis and cancer. Thus, in this review, the application of different nanoparticles for the treatment of these four important diseases (Alzheimer’s disease, tuberculosis, leprosy and cancer) as well as for the effective delivery of drugs used in these diseases has been presented systematically. Although nanoformulations have many advantages over traditional therapeutics for treating these diseases, nanotoxicity is a major concern that has been discussed subsequently. Lastly, we have presented the promising future prospective of nanoparticles as alternative therapeutics. In that section, we have discussed about the futuristic approach(es) that could provide promising candidate(s) for the treatment of these four diseases.
Healing From Home: Examination of an Online Mindfulness-Based Tinnitus Stress Reduction Course During the 2020 COVID Pandemic
Authors: Gans Jennifer J. , Holst Jennifer , Holmes Corrie , Hudock Daniel
Published: January 2023

Purpose:

The purpose of this study was to assess the effectiveness of an Internet delivered Mindfulness Based Tinnitus Stress Reduction (i-MBTSR) program during the COVID-19 pandemic. Tinnitus, often a chronic condition, is experienced by 15% of the population. For those with severe, bothersome tinnitus, quality of life is reduced and the treatment options are limited. We evaluated an approach intended to decrease tinnitus-related distress.

Method:

This study examined the data collected for an online i-MBTSR course using a retrospective design. The intervention included an 8-week self-paced i-MBTSR course, including didactic information about mindfulness and tinnitus, as well as meditation practices. Outcome measures included the Tinnitus Functional Index (TFI) and Perceived Stress Scale (PSS), which were measured at four time periods. These time points included pretreatment, midtreatment at 3 weeks, immediately posttreatment, and at 6-month follow-up.

Results:

Forty-three participants completed the intervention. The mean preintervention tinnitus severity rating was 59.96 (“severe tinnitus”) as measured by the TFI. Mean TFI scores dropped to 44.16 (
p
< .001) at midtreatment and to 34.23 (
p
= .001) at posttreatment. Repeated-measures analysis of variance and multivariate analysis of variance tests were conducted to determine changes in the two scales at the four time periods. There were significant differences in perceived stress and tinnitus self-function found in all measures and submeasures between the pre-, mid-, and posttreatment time points with the exception of the TFI Auditory subtest. These gains remained significant for those who completed the 6-month follow-up.

Conclusions:

The i-MBTSR course appears to be a viable and effective treatment modality. A shorter 3-week course may be effective. Case-control studies to more systematically investigate the effectiveness of i-MBTSR for tinnitus are required.
Self-Reported Communication Attitudes of Children With Childhood Apraxia of Speech: An Exploratory Study
Authors: Keller Sydney , Maas Edwin
Published: January 2023

Purpose:

Much of the research literature on childhood apraxia of speech (CAS) has focused on understanding, diagnosing, and treating the impairment, rather than examining its functional effect on children's daily lives. This study focuses on the Personal Factors component of the World Health Organization International Classification of Functioning, Disability and Health–Children and Youth Version Framework. Specifically, the purpose was to examine the self-reported communication attitudes of children with CAS.

Method:

Two validated communication attitude questionnaires were administered to 12 children with CAS enrolled in an intensive speech-focused intervention (age range: 4–10 years old). Children's scores were compared to the questionnaires' typically developing norms. Descriptive analyses explored relationships between communication attitude and CAS severity, caregiver perceptions of communicative participation, frustration ratings during therapy, and change in communication attitude over a brief time.

Results:

Older (ages 6–10 years) but not younger (ages 4–5;11 [years;months]) children with CAS were more likely to have negative attitudes about their speech. No clear relationships were observed between communication attitudes and caregiver perceptions of communicative participation; small positive relationships were observed between communication attitude and frustration during therapy. For the younger children, there was also a relationship with CAS severity. For most children, no change in communication attitude was observed over a brief period, though one child appeared to develop more negative and one appeared to develop more positive attitudes.

Conclusions:

These initial findings suggest that older children with CAS may be at greater risk for negative communication attitudes than their peers without CAS. The findings also highlight the need to include more child self-report measures in research. Further implications for CAS assessment and intervention are discussed.

Supplemental Material:

https://doi.org/10.23641/asha.21834432
The Role of Naturalistic Developmental Behavioral Interventions in Early Intervention for Autistic Toddlers: An Observational Study
Authors: Lee Jordan , Sone Bailey , Rooney Tara , Roberts Megan Y.
Published: January 2023

Purpose:

Naturalistic developmental behavioral interventions (NDBIs) have demonstrated initial promise in facilitating social communication development for autistic toddlers, but their highly structured protocols may be a barrier toward their use by early intervention (EI) providers who must individualize intervention according to family-centered principles. This study aimed to characterize the extent to which EI speech-language pathologists (SLPs) use NDBI strategies, and the range of skills and behaviors addressed during their EI sessions, to contextualize the role of NDBIs within the scope of needs of families with autistic children in EI.

Method:

This observational study included 25 families with an autistic toddler and their EI SLP. One home-based session was recorded for each family, and an observational measure was used to describe SLPs' NDBI strategy use. Qualitative content analyses were also used to characterize the strategies SLPs recommended to families, and the child skills and behaviors they discussed.

Results:

SLPs did not implement NDBI strategies with high quality, but they implemented developmental NDBI strategies with significantly higher quality than behavioral NDBI strategies. SLPs discussed many strategies and skills across disciplines within the session.

Conclusions:

SLPs may require further training to implement NDBI strategies, but given the breadth and depth of skills addressed during sessions, researchers should investigate and report on the impact of NDBIs on a wider range of communication skills and developmental domains. This will facilitate clinical decision making and make these interventions better aligned with family-centered EI principles.

Supplemental Material:

https://doi.org/10.23641/asha.21834480
Embedding Executive Function Training Into Early Literacy Instruction for Dual Language Learners: A Pilot Study
Authors: Goodrich J. Marc , Peng Peng , Bohaty Janet , Leiva Sergio , Thayer Lauren
Published: January 2023

Purpose:

Early literacy skills are key indicators of future reading development for young dual language learners (DLLs). Additionally, emerging evidence indicates that young children's executive function (EF) skills are uniquely associated with elementary school reading outcomes (Ribner et al., 2017). Therefore, the purpose of this pilot study was to evaluate the potential for embedding strategies to support EF development within evidence-based early language and literacy instruction for young DLLs.

Method:

Sixty-nine preschool DLLs were randomly assigned to one of three treatment groups: a business-as-usual control group (BAU), a group that received early literacy instruction only (EL group), and a group that received early literacy instruction with embedded EF strategies (EL + EF group). The intervention focused on improving children's early literacy skills, including letter–name knowledge, phonological awareness, and oral language. Children completed assessments of early literacy and EF immediately before and after the intervention.

Results:

The EL and EL + EF groups significantly outperformed the BAU control group for two early literacy outcomes, and effects of evidence-based early literacy instruction were strongest for children with poor EF skills. Results indicated that there were no significant differences between the EL + EF and EL groups.

Conclusions:

This pilot study indicated that there was no significant benefit to adding supports for EF skills within evidence-based early literacy instruction. Additional research is needed with larger samples to replicate observed effects.

Supplemental Material:

https://doi.org/10.23641/asha.21834465
A 1.0 fJ energy/bit single‐ended 1 kb 6T SRAM implemented using 40 nm CMOS process
Authors: Wang Chua‐Chin , Sangalang Ralph Gerard B. , Tseng I‐Ting , Chiu Yi‐Jen , Lin Yu‐Cheng , Jose Oliver Lexter July A.
Published: January 2023

An ultra‐low‐energy SRAM composed of single‐ended cells is demonstrated on silicon in this investigation. More specifically, the supply voltages of cells are gated by wordline (WL) enable, and the voltage mode select (VMS) signals select one of the corresponding supply voltages. A lower voltage is selected to maintain stored bit state when cells are not accessed, lowering the standby power. And when selecting a cell (i.e. WL is enabled) to perform the read or write (R/W) operations, the normal supply voltage is used. A 1‐kb SRAM prototype based on the single‐ended cells with built‐in self‐test (BIST) and power‐delay production (PDP) reduction circuits was realised on silicon using 40‐nm CMOS technology. Theoretical derivations and simulations of all‐PVT‐corner variations are also disclosed to justify low energy performance. Physical measurements of six prototypes on silicon shows that the energy per bit is 1.0 fJ at the 10 MHz system clock.
A PVT resilient true‐time delay cell
Authors: Yarahmadi Ahmad , Jannesari Abumoslem
Published: January 2023

A true‐time delay (TTD) cell in TSMC 0.18 μm CMOS technology for 1–5 GHz applications is presented. Process variations, ageing effects, field variations, and other non‐idealities have some impacts on the TTD cell's devices. One of the vulnerable specifications of TTD cells is their delay variation. While the TTD cell works in a delay line, the cell must have a constant and robust delay in the frequency band. For this matter, the body bias technique is presented and applied to the inductor‐less TTD cell. With this technique, the threshold voltage can be manipulated intentionally. So, any variation in this voltage can be compensated with the body biasing of transistors. The simulation results show the TTD cell's robust performance against non‐idealities, while delay variation improves more than 3× times in the frequency band of interest. This TTD cell provides a 50.95 pS delay with only 2% variation, while S11 and S22 parameters are lower than −10 dB in the 1–5 GHz frequency band. IIP3 of the TTD cell is about 2.7 dBm, and the power consumption is 20.5 mW.
Context‐aware target classification with hybrid Gaussian process prediction for cooperative vehicle safety systems
Authors: Valiente Rodolfo , Raftari Arash , Mahjoub Hossein Nourkhiz , Razzaghpour Mahdi , Mahmud Syed K. , Fallah Yaser P.
Published: January 2023

Vehicle‐to‐Everything (V2X) communication has been proposed as a potential solution to improve the robustness and safety of autonomous vehicles by improving coordination and removing the barrier of non‐line‐of‐sight sensing. Cooperative Vehicle Safety (CVS) applications are tightly dependent on the reliability of the underneath data system, which can suffer from loss of information due to the inherent issues of their different components, such as sensors' failures or the poor performance of V2X technologies under dense communication channel load. Particularly, information loss affects the target classification module and, subsequently, the safety application performance. To enable reliable and robust CVS systems that mitigate the effect of information loss, a Context‐Aware Target Classification (CA‐TC) module coupled with a hybrid learning‐based predictive modeling technique for CVS systems is proposed. The CA‐TC consists of two modules: a Context‐Aware Map (CAM), and a Hybrid Gaussian Process (HGP) prediction system. Consequently, the vehicle safety applications use the information from the CA‐TC, making them more robust and reliable. The CAM leverages vehicles' path history, road geometry, tracking, and prediction; and the HGP is utilized to provide accurate vehicles' trajectory predictions to compensate for data loss (due to communication congestion) or sensor measurements' inaccuracies. Based on offline real‐world data, a finite bank of driver models that represent the joint dynamics of the vehicle and the drivers' behavior is learned. Offline training and online model updates are combined with on‐the‐fly forecasting to account for new possible driver behaviors. Finally, the framework is validated using simulation and realistic driving scenarios to confirm its potential in enhancing the robustness and reliability of CVS systems.
Mutual information‐based constant‐modulus waveform design for multiple‐input‐multiple‐output radar in spectrally crowded environment
Authors: Wang Xuyang , Tang Bo , Li Da , Wu Wenjun
Published: January 2023

This study considers designing constant‐modulus waveforms for multiple‐input‐multiple‐output radar in spectrally crowded environment. The mutual information is used as the waveform design metric. A constant‐modulus constraint is imposed on the waveforms to improve the hardware efficiency. To enhance the spectral compatibility of the transmit waveforms, a precise control on the interference energy produced on each reserved bandwidth is considered. To tackle the multi‐spectrally constrained waveform design problem, a minorisation‐maximisation based method is developed, and a quadratic function to minorise the objective function is derived. Then an alternating direction method of multipliers is used to tackle the quadratically constrained quadratic programming problem at each iteration. The effectiveness of the presented algorithm is demonstrated via simulation results.