bluuebunny/crossref_metadata_2025 huggingface dataset:
Expert Consensus on S-Etodolac in the Management of Osteoarthritis from an Indian Perspective
Authors: Prabhoo Ram , Naik Rajeev , Sauhta Ravi , K. Rao U. R. K. , Singh Amulya Kumar , Ramalingaiah A. , Gawhale Sangeet , Ajgaonkar Amit , Mukherjee Kiran Kumar , Kulkarni Sunil , Arumugam S. , Raja T. V. , Wade Roshan , Swami Onkar C. , Kulkarni Ketan
Published: July 2023

Osteoarthritis (OA) is the most frequent joint disease in India. The current treatment guidelines suggest nonsteroidal anti-inflammatory drugs (NSAIDs) for the management of OA based on the patient's risk profile. Etodolac, a preferential cyclooxygenase 2-selective, chiral NSAID, has a long and well-established record of being an effective therapy for acute musculoskeletal pain, OA, and rheumatoid arthritis. Studies have shown that the pharmacological properties of R and S-enantiomers of etodolac differ profoundly; S-Etodolac is responsible for the majority of the anti-inflammatory activity, whereas the R-form is almost inactive. The objective was to develop evidence-based practical consensus recommendations for the management of OA with chirally pure S-Etodolac in the Indian settings. Literature review was carried out from the PubMed Database to identify relevant articles between January 1980 and May 2022 using keywords such as “osteoarthritis,” “NSAIDs,” “Etodolac,” “chirality,” “S-Etodolac,” “consensus,” and “management.” Extensive literature review was done. Further, a committee of 13 orthopedic specialists from India with significant experience in managing patients with OA was constituted. The key areas of discussion were as follows: (i) Selection of medications; (ii) role and risk/benefit profile of etodolac versus other NSAIDs; (iii) patient subgroups who would benefit from S-Etodolac oral therapy; and (iv) S-Etodolac gel in the management of OA. Experts strongly recommended S-Etodolac therapy in OA patients at increased risk of NSAID-related gastrointestinal complications, cardiovascular risk, and renal impairment. The patient pool that would derive maximum benefit from a combination of S-Etodolac and paracetamol therapy includes: (i) OA patients with the acute phase of the disease with reactive synovial effusion or acute painful inflammatory arthritis; (ii) moderate pain; and (iii) acute exacerbation of OA. This article can guide medical practitioners in clinical decision-making while choosing an appropriate NSAID therapy for the management of OA.
PECULIARITIES OF THE MASTICATORY APPARATUS OF GUINEA PIGS (Cavia porcellus)
Authors: SPATARU Constantin , SPATARU Mihaela Claudia
Published: July 2023

Guinea pigs (Cavia porcellus) are rodents that feed on grassy plants, buds and sprouts, with cheek teeth having specialised abrasive surfaces for plant grinding. In analysing the prehension and trituration ways of guinea pigs, many differences concerning mandible conformation, the positioning of cheek teeth and the morphology of the masticatory muscles compared to other rodents were found. Masticatory muscles of guinea pigs are predominant compared to the mimetic muscles which are reduced. Compared to other rodents, in guinea pigs, inside the tendon thickness of the superficial part of the masseter muscle there are two rounded cartilaginous structures such as sesamoids. The dorsal one is larger, measuring about 3–4 mm in diameter having the role of reducing pressure on the tendon when it passes over the mandible ridge. The other is ventrally placed, about 2–3 mm in size and protects the tendon of the superficial part of the masseter muscle when it passes over the ventral tubercle of the mandible.
Estuarine flocculation dynamics of organic carbon and metals from boreal acid sulfate soils
Authors: Virtasalo Joonas J. , Österholm Peter , Asmala Eero
Published: July 2023

Abstract. Flocculation of riverine dissolved organic matter to the particulate form in estuaries is an important mechanism for capturing dissolved metals to
newly formed organic particles, regulating the metal transport from land to sea. The process is particularly relevant for rivers draining boreal
acid sulfate soils of western Finland, which are known to deliver large amounts of trace metals with detrimental environmental consequences for the
recipient estuaries in the eastern Gulf of Bothnia in the northern Baltic Sea. This is the first study to investigate dissolved metal (Al,
Fe, Mn, Co, and Cu) association with flocculating organic particles in the laboratory, by mixing of acidic metal-rich
water from acid-sulfate-soil-impacted rivers and particle-free artificial seawater. Water samples were collected in April 2021 from the Laihianjoki
and Sulvanjoki rivers in western Finland. Experiments with an in situ laser-diffraction-based particle size distribution sensor and a
multiparameter water quality sonde were run to continuously monitor the development of a suspended particle pool over the salinity gradient from 0
to 6, corresponding to the salinity range observed in these estuarine systems. Flocculator experiments with discrete salinity treatments were carried
out to investigate metal behaviour with the collection of flocculated material on glass fibre filters. Filtrate was analysed for coloured dissolved-organic-matter absorbance and fluorescence for the characterization of potential changes in the organic matter pool during the flocculation
process. Retentate on the filter was subjected to persulfate digestion of organic particles and metal oxyhydroxides (pH < 2.3), and the
digestion supernatants were analysed for metal concentrations. The laboratory experiments showed strong transfer of Al and Fe already
at a salinity of 0–2 to newly formed organically dominated flocs that were generally larger than 80 µm. Very strong coupling between the
decrease in humic fluorescence and the increase in organically bound Al demonstrated that Al transfer to the flocs was stronger than
that of Fe. The flocs in the suspended particle pool were complemented by a smaller population of Al- and Fe-oxyhydroxide-dominated flocculi (median size of 11 µm) after pH exceeded ca. 5.5. Cobalt and Mn transfer to the particle pool was
weak, although some transfer to Mn oxyhydroxides as well as Co association with the flocs took place. Up to 50 % of Cu was
found to be bound to humic substances in the flocs in the river waters, and this proportion did not significantly change during mixing with
seawater. The findings of this study demonstrate that salinity and pH are important independent but connected controls of the flocculation behaviour
of dissolved metals from boreal acid sulfate soils and the seaward transport and environmental consequences of the metals in the marine
environment.
Review article: Snow and ice avalanches in high mountain Asia – scientific, local and indigenous knowledge
Authors: Acharya Anushilan , Steiner Jakob F. , Walizada Khwaja Momin , Ali Salar , Zakir Zakir Hussain , Caiserman Arnaud , Watanabe Teiji
Published: July 2023

Abstract. The cryosphere in high mountain Asia (HMA) not only sustains the livelihoods of people residing downstream through its capacity to store water but also holds the potential for hazards. One of these hazards, avalanches, so far remains inadequately studied, as the complex relationship between climate and potential triggers is poorly understood due to lack of long-term observations, inaccessibility, severe weather conditions, and financial and logistical constraints. In this study, the available literature was reviewed covering the period from the late 20th century to June 2022 to identify research and societal gaps and propose future directions of research and mitigation strategies. Beyond scientific literature, technical reports, newspapers, social media and other local sources were consulted to compile a comprehensive, open-access and version-controlled database of avalanche events and their associated impacts. Over 681 avalanches with more than 3131 human fatalities were identified in eight countries of the region. Afghanistan has the highest recorded avalanche fatalities (1057), followed by India (952) and Nepal (508). Additionally, 564 people lost their lives while climbing peaks above 4500 m a.s.l., one-third of which were staff employed as guides or porters. This makes it a less deadly hazard than in the less populated European Alps, for example, but with a considerably larger number of people affected who did not voluntarily expose themselves to avalanche risk. Although fatalities are significant, and local long-term impacts of
avalanches may be considerable, so far, limited holistic adaptation or
mitigation measures exist in the region. These measures generally rely on
local and indigenous knowledge adapted to modern technologies. Considering
the high impact avalanches have in the region, we suggest to further develop adaptation measures including hazard zonation maps based on datasets of historic events and modelling efforts. This should, however, happen acknowledging the already existing knowledge in the region and in close coordination with communities, local government and civil society stakeholders. More research studies should also be attempted to understand the trends and drivers of avalanches in the region.
Situation Epidemio-Clinique De La Dermatose Nodulaire Contagieuse Bovine Dans Le District De Mananjary
Authors: RAKOTOVAO-RAVAHATRA Zafindrasoa Domoina , Rakotovao-Ravahatra Joely Nirina , Randrianarison Joseph Adrien , Rakotovao Andriamiadana Luc
Published: July 2023

La dermatose nodulaire contagieuse représente un problème majeur de la santé des bovins à Madagascar. La présente étude a pour objectif de décrire la situation épidemio-clinique de la dermatose nodulaire contagieuse bovine dans le district de Mananjary. Il s’agit d’une étude descriptive et transversale a été réalisée du mois d’octobre 2015 au mois de février 2016 dans le district de Mananjary. En termes de résultats, la prévalence globale de la dermatose nodulaire contagieuse est de 20,96%. L’étude des facteurs de risque montre que la persistance de ces maladies est significativement liée à la race, au sexe et à l’état d’embonpoint. En conclusion, la dermatose nodulaire des bovins reste encore une menace pour le bétail dans notre pays. Le diagnostic étiologique précis et les traitements efficaces à long terme sont indispensables pour pouvoir les maitriser et les éradiquer.
Microdebrider Intracapsular Tonsillectomy: A Narrative Review
Authors: Kurudamannil Reuel Abraham , Shah Arafat Anis , Baqri Maryam Irshad , Hussaini Syeda Nida , Bakour Maen Ali
Published: July 2023

Introduction: Microdebrider intracapsular tonsillectomy is a relatively recent surgical procedure used to treat various tonsil and adenoid disorders. Unlike traditional tonsillectomies, which involve the complete removal of the tonsils, this technique uses high-speed rotation to remove only the diseased tissue, allowing for more precise removal while preserving the surrounding healthy tissue. This procedure has gained popularity in recent years due to its ability to reduce postoperative pain and allow for a quicker return to regular eating habits, especially in children with tonsillitis and sleep apnea. In this review, we aim to explore the efficacy, safety, and limitations of microdebrider intracapsular surgery in the management of otolaryngologic conditions.Methods: A preliminary search was conducted on several databases to identify relevant articles on tonsillectomy. The study focused on keywords such as "microdebrider", "Coblation tonsillectomy", "intracapsular tonsillectomy", “conventional tonsillectomy” and "minimally invasive tonsillectomy" and included patients with recurrent and/or chronic tonsillitis and patients with tonsillar hypertrophy with symptoms of obstructive sleep troubles such as persistent snoring. Conclusion: Microdebrider Intracapsular tonsillectomy is a surgical procedure used for various conditions related to the tonsils, with less tissue removed than traditional tonsillectomy. It causes less pain, has a shorter recovery time, and has fewer complications. However, there is a small risk of tonsil regrowth and the need for an additional procedure. The decision on which method to use depends on the patient's medical history and the surgeon's recommendation, and it is essential to understand potential complications and seek medical attention promptly if needed.
The Growth And Yield Of Sweet Corn With Dolomite Application On Ultisol In Limau Manis
Authors: Thi Hong Tho Nguyen , Agustian Agustian , Hermansah Hermansah
Published: July 2023

The area of sweet corn in Indonesia has been increasing due to the demand for this product in the country's market. The absence of fertile soil for the growth of sweet corn is one of the frequent issues encountered during cultivation. Therefore, it needs to implement the necessary procedures to enhance the nutrient in the soil. This study aimed to determine how sweet corn will grow and yield on Ultisol in Limau Manis using dolomite. This study was conducted at the greenhouse at Andalas University from July to November 2022. Lime was not added to the first treatment V1, and dolomite was added to the second treatment V2 at a rate of 6.25 tons/ha. The period of growth for the corn in V2 was shorter than in V1, with the reproductive stage earlier in treatment V2 focusing on fruit development. Compared to the treatment without lime, adding dolomite produced good outcomes regarding fruit weight at harvest, seed weight, stem weight, and corn root weight. The time of silk appearance in the V1 treatment was around 65 days after sowing, and in the V2 treatment was around 64 days after sowing. The yields were greater for the lime treatment (6.82 tons/ha) than for the control (6.31 tons/ha), but there was no statistically significant difference between the two treatments. Adding lime increased the soil's pH, helped the corn grow well, and obtained a yield better than the soil without lime added.
The Influence Of Sociocultural Factors On Stunting Incidents (Qualitative Studies In Rural)
Authors: Hastuti Lidia
Published: July 2023

Introduction: The problem of stunting that occurs in childhood has an impact on morbidity, mortality, impaired physical growth, impaired mental and cognitive development, and affects motor development. The disturbances that occur tend to be irreversible. The direct causes of stunting include inadequate nutritional intake and infectious diseases. Indirectly stunting can be caused by factors such as family food security, parenting style, inadequate health and environmental health services, education, poverty, and socio-culture. The research aims to determine the influence of social, economic, and cultural factors on the incidence of stunting in Bange village. Method: Qualitative study with a phenomenological approach, with a total of 9 participants. Collecting data by conducting in-depth interviews, testing the validity and reliability of the research was carried out using the triangulation method, and analyzing data using thematic analysis. Result: This study found several factors causing stunting, namely the use of contraception is not optimal, the spacing of pregnancies is too close, pregnancy at a young age, implementation of a clean and healthy lifestyle that is less than optimal, lack of nutritional supplements in pregnant women and babies and lack of knowledge of mothers about food nutrition during pregnancy and after the child is born. Social factors and community habits are related to the incidence of stunting, namely family economic factors, family parenting patterns that are not optimal, young marriages, young pregnancies, and spacing of pregnancies that are too close, and parenting patterns in the family. There was no specific culture/culture that was suspected of being the direct cause of stunting in toddlers.Keywords: social factors, rural, stunting
Changes in tra catfish flesh meat (Pangasianodon hypophthalmus) during refrigerator storage and the lipid properties of flesh meat
Authors: MINH Thuy Le Thi , Do QUYNH Nguyen , NGUYEN Muoi
Published: July 2023

In this study, the lipid properties of tra catfish flesh meat (Pangasianodon hypophthalmus) during refrigerator storage as well as the properties of oil extracted from tra catfish flesh meat were investigated. The quality of the samples was maintained, with lipid content and peroxide value falling within the acceptable range after 15 days of storage. The yield of oil extracted using isopropanol:hexane at a ratio of 2:3 was higher (56.2%) than that extracted using ethanol:hexane at a different ratio. Isopropanol:hexane (2:3) also showed the highest L* (lightness/brightness) value (33.35) and the lowest b* (yellowness/blueness) value (7.35). The polyunsaturated fatty acid levels as well as the omega 3 and 6 fatty acid levels of oil were highest in this solvent at a ratio of 2:3. Thus, tra catfish flesh meat could be used as a material for lipid extraction.
Unlocking the Potential: Exploring Interoperability Challenges and Solutions in Digital Health Ecosystems
Authors: KOTSIOPOULOS Dr Ioannis , BERLER Dr Alexander
Published: July 2023

Digital health has the potential to revolutionize and democratise healthcare delivery in ways that could not be imagined a few years ago, bringing humanity closer to the vision of universal health coverage. At the same time though, healthcare systems across the globe are facing unprecedented challenges due to the ageing population, the lack of adequate resources and emerging public health risks such as the recent pandemic. Among the many com- peting priorities, healthcare leaders need to accelerate dig- ital transformation and ensure that patients and clinicians will soon be able to harness the benefits of the new tech- nologies. One of biggest challenge remains the lack of inter- operability between systems. National and EU wide initia- tives have the potential to unlock some of the obstacles, however significant risks lie ahead. To address the interop- erability problem in Greece, significant work has been done for the development of the Greek National eHealth Inter- operability Framework (NeHIF) which could be the basis for the implementation of the Greek Digital Transformation Programme. The creation of a digital ecosystem of certified vendors could accelerate the implementation of this pro- gram and minimise the relevant risks.
Emergency Lower Segment Cesarean Section with Pre-Eclampsia With Antepartum Haemorrhage (Abruptio Placenta): A Case Report
Authors: Ambule Kalyani
Published: July 2023

Background: : In lower segment caesarean section, the infant is extracted by a trans-peritoneal technique, which involves making an incision in the lower section. Unless otherwise noted, it is the only procedure used in modern obstetrics. In infected cases, the procedure using an extra peritoneal route to the lower segment is no longer necessary. High blood pressure is a potentially serious consequence of pregnancy. Antepartum hemorrhage is defined as bleeding from or into the vaginal tract that occurs between 24 weeks and the birth of the baby. Placenta praevia and placental abruption are the two most common causes of APH. Case history: A 27 year old female with obstetric score G2P1L1, 29.6 weeks gestational age with previous full term normal delivery came to Acharya Vinoba Bhave Rural Hospital Sawangi Meghe Wardha on date 29th November 2021 with complaints of bleeding per vagina and pain in abdomen. Patient had been advised to get admitted in OBGY unit and investigated with ultrasonography, Doppler and bed rest. Vital monitoring indicated afebrile, pulse was 94bpm, blood pressure 140/90 mmHg at the time of admission. Interventions: Patient had been immediately managed with vitals/ fetal heart rate/non-stress test monitoring, kept nil by mouth, Foley’s catherization, part preparation, 2 units PRC reserved. IV fluids were started with 1gm Ceftriaxone antibiotics, 40mg Pantoprazole, 12mg injection Dexamethasone IV STAT. The aim of this treatment is to safeguard mother’s as well as baby’s life. Outcome: Over this period of treatment, a male baby weighing 1.2kg was delivered with emergency LSCS on 29th of November 2021, after which baby was transferred to NICU for further needs. Placenta was extracted with intact membrane. Discussion: Patient’s condition was under controlled as per her vitals monitoring, she was afebrile, and blood pressure was 110/70mmHg. Patient’s response was quite better to the treatment.
The Principle of Energy Solidarity in European Union Law
Authors: Borges Taveira Luís Felipe , Campos de Carvalho Daniel
Published: July 2023

The Principle of Energy Solidarity in European Union Law: Nord Stream 2 as a Common Thread

Changes in the European natural gas market that were planned to enable the installation of the Nord Stream 2 gas pipeline are wrapped in a regulatory dome. Gazprom, a Russian state-owned company, is concerned with demonstrating that the project is compatible with European integration. The legal debate expands when it becomes clear that political, regulatory and legal institutions, such as the Court of Justice of the European Union, use the principle of energy solidarity to justify European action in this market and its application at the national level. The general hypothesis to be answered is: does the principle of energy solidarity satisfy the European pretensions about the gas pipeline? Through a documental and bibliographical research, the supranational norms and jurisprudence on the gas market will be adopted as a starting point; later on, an analysis of the judicial decisions on the extension of the competence of the European norms and a theoretical assessment of the principle of energy solidarity will be conducted.
Colonial Legacy of Pakistan and Genesis of a New Constitution
Authors: Akhtar Zia
Published: July 2023

Colonial Legacy of Pakistan and Genesis of a New Constitution: Legitimacy of Power, Land Ownership and the Enlightenment

The state of Pakistan came into being in 1947 after inheriting the laws of the British colonial rule based on a framework that has allowed the land-owning stakeholders to compete for influence and power. The constitution of the country has been reconfigured to suit its rulers, including the military in power and the largest constituency is the land-owning class which maintains its presence in all the elected assemblies that have formed the legislature in Pakistan. The ideological underpinning and the electoral system have been inherited from the British rulers and with it the zamindari system also which provides the landed gentry its power base. The issue is to what extent is the feudal system tilted towards maintaining the status quo that gives those in the land-owning class their privileged status. The power of the nobility known locally as the jagirdars command a mystical allegiance drawn from their privileges of birthright. This article defines the colonial legacy that has permeated the constitutional framework through laws instituted by British rule which persists in the corridors of the legal and political hierarchy. The argument presented is that Pakistan has to sever its colonial inheritance and emerge as a redefined state by adopting the intellectual preamble of the French Enlightenment that will bring about a revised system that can also be sustained in the light of dispensation based on a social contract.
The Quality and Constitutionality of Enabling Provisions in Legislation in St. Kitts and Nevis
Authors: Saurie Slack Michelle Jan
Published: July 2023

The Quality and Constitutionality of Enabling Provisions in Legislation in St. Kitts and Nevis

Notwithstanding historical arguments surrounding the constitutionality of the delegation of legislative power, the practice is now an accepted feature of the legislative process in St. Kitts and Nevis to the extent that it is more likely than not that laws are passed which include provisions enabling ministers or other senior public officials to make subsidiary legislation. The Eastern Caribbean Supreme Court has considered the question of the constitutionality of the delegation of legislative power and has ruled that the practice is ‘not unconstitutional per se’. The critical question is, what makes it constitutional or not and what is necessary to ensure that the making of subsidiary legislation is within the bounds of the Constitution. Stated otherwise, what is necessary to ensure an effective enabling clause?

This article highlights how it is necessary to include measures within enabling clauses that circumscribe the exercise of delegated legislative power and require parliamentary oversight of the making of subsidiary legislation. By so doing, the quality of enabling clauses in St. Kitts and Nevis legislation can be greatly improved.
Full Issue
Authors: Journal system
Published: July 2023

abstract
Studies of beta-cardiotoxin from king cobra venom on rat cardiac functions: Effect on isolated single cardiomyocyte
Authors:   , Lertwanakarn Tuchakorn
Published: July 2023

Beta-cardiotoxin (ß-CTX), a novel protein isolated from the King cobra (Ophiophagus hannah) venom has previously been proposed as a beta-blocker candidate. However, cellular mechanisms of ß-CTX on cardiomyocyte is unknown. This study aimed to evaluate the impact of ß-CTX on isolated rat cardiomyocyte function and the cardiac myofibrillar activity, and to explore involvement of ß-adrenergic receptor (ß-AR) signaling pathway. ß-CTX was isolated and purified using two-step chromatographic method and confirmed by N-terminal sequencer. The function of ß-CTX on cardiomyocyte was compared to propranolol in 3 conditions, basal state, with isoproterenol (ISO), and with forskolin (FSK). ß-CTX exhibited more potency than propranolol to suppress the myocyte contraction without altering calcium transient. However, ß-CTX prolonged the calcium decaying resulted in negative lusitropy. Although cardiac functions were blunted by ß-CTX in the presence of either ISO or FSK, the phosphorylation of the downstream ß-AR signaling sites were not affected. The compound was further tested on the cardiac myofibrillar ATPase activity and the kinetics. ß-CTX suppressed the maximal ATPase activity without changing Ca2+-sensitivity of the myofibril. In conclusion, the mechanism of ß-CTX on cardiomyocyte was not mediated through classical ß-AR pathway but directly suppress the actomyosin ATPase activity, depress the myofilament kinetics, and hence, reduce the cardiomyocyte functions.
Labour Emigration and Income Inequality Effects in Sending Countries: Evidence from Nigeria
Authors: Oyegoke Ebunoluwa O.
Published: July 2023

Labour emigration is considered an alternative source of income and earnings in developing countries, particularly, those with large populations and high unemployment rates. This paper empirically investigates the relationship between income inequality and labour emigration, and the effects of labour emigration on income inequality in the source country using Nigeria as evidence. Annual time series on income inequality (Gini coefficient), remittance inflow, net migration rate and others are variables used for the model covering the span of 41 years (1980-2021) Correlation Matrix and the Ordinary Least Square (OLS) models are employed to estimate the model. The findings reveal that the correlation relationship between labour emigration and income inequality in sending country (Nigeria) is a very weak positive one (0.39). While the OLS shows an insignificant positive relationship. This implies that a direct significant link between income inequality and labour emigration at the macro level was not established. Therefore, labour mobility should not be restricted, but rather restructured to maximise the full benefits at the macro level in Nigeria.
,,Columna lui Traian”. O pagină din istoria presei românești
Authors:   Facultatea de Istorie, Universitatea din București, Gudin Cristina
Published: July 2023

„Trajan's Column”, the magazine founded by Bogdan Petriceicu Hașdeu in 1870, has been contributing to improving the cultural level of its readers for almost a decade. The profile of the magazine has changed over time, after only a few years the political articles giving way to cultural controversies with Titu Maiorescu and his protégés promoted in „Literary Conversations”. However, beyond the dispute with the Junimists, politicians and the monarchy, the magazine has constantly promoted folk creations and cultured literature. Special attention was paid to history and linguistics as „Trajan's Column” became a cultural and scientific journal. Many pages have been dedicated to historical studies, etymological analysis, document editing. There is no lack of articles with medical and economic content, or information about the scientific projects of Romanian and foreign historians and linguists. At the same time, the readers were informed about the new editorials, as well as the quality of the most recent specialized works, which are the subject of competent reviews. „Trajan's Column” was a reference magazine in the Romanian publishing landscape in the modern era, cultivating the interest of contemporaries for the historical past, but also for literary creations.
Finanțarea, promovarea și valorificarea științifică a revistei „Arhivele Olteniei” (1922–1946
Authors:   Institutul de Cercetări Socio-Umane „C.S. Nicolăescu-Plopşor”  din Craiova, al Academiei Române, Mitu Maria Narcisa
Published: July 2023

In Oltenia, both within modern times and the interwar period, Craiova has distinguished as the most significant historical, economic and cultural centre. Culturally, „Arhivele Olteniei” enlists as „one of the most valuable” publications of the time diverting from the other prints by its encyclopaedic profile. Begins in 1922, at the initiative of doctor Charles Laugier as head and an editorial board made up of teachers and specialists: Stefan Ciuceanu (Craiova), T. G. Bulat (Ramnicu Valcea), Al. Barcacila (Tr. Severin), C. D. Fortunescu- the editorial secretary, as a quarterly publication and the forthcoming year as bimonthly issue. Dr. Laugier reports that the idea of editing this kind of journal is earlier, but he hesitated a lot mainly due to financial difficulties which publications faced overall, but particularly the scientific ones at that time. Although the threat of closing the publisher for material causes frequently hovered over the journal, it managed to emerge and to be valued for two decades. Ion Bianu appreciated ”Arhivele Oltenei” journal as „an invaluable treasure” for current and future historians.
Un francez cu suflet de oltean: Charles Laugier. Însemnări despre activitatea medicală, culturală și publicistică
Authors:   Institutul de Cercetări Socio-Umane „C.S. Nicolăescu-Plopşor”  din Craiova, al Academiei Române, Mitu Narcisa Maria , Ilin Grozoiu Loredana Maria ,   Institutul de Cercetări Socio-Umane „C.S. Nicolăescu-Plopşor”  din Craiova, al Academiei Române
Published: July 2023

The mission which we undertook on the occasion of celebrating a century since the publication of the first issue of the "Arhivele Olteniei" magazine, is to bring to the audience's attention the actions, the deeds of a great lover of Craiova culture from the beginning of the 20th century. In this article we will praise the personality and activity of Dr. Charles Hyppolite Laugier, founder of the publication "Arhivele Olteniei", who showed tenacity and a spirit of organization and enthusiasm in his approach to the medical, cultural and scientific field of Oltenia.
ALEXANDRU BĂRCĂCILĂ ȘI REVISTA „ARHIVELE OLTENIEIˮ
Authors:   Direcției Județene Mehedinți a Arhivelor Naționale, Rățoi Tudor
Published: July 2023

Alexandru Bărcăcilă (March 31, 1876, Bughea de Sus, Muscel - February 6, 1970, Bucharest) - one of the great personalities of Oltenia, archaeologist, professor and founder of cultural institutions, had close ties with the magazine Arhivele Olteniei. He created the magazine together with Dr Ch. Laugier, C.D. Fortunescu, Șt. Ciuceanu and others and supported it during 1922-1943, when it was printed. As a member of its board, he promoted the magazine in Mehedinți, and as a scholar he published numerous articles, studies and reading notes on subjects beyond his specialty - classical archeology and Latinism - but also more recent history documents related to the area where he lived and worked. Many of these concerned: the Romanian revolution of 1821 and its leader, Tudor Vladimirescu, as well his friend, Nicolae Zoican, villages and estates of Mehedinți (e.g., Nadanova, Studina), Roman and Romanian antiquities of Hațeg, funerary and religious monuments of Drobeta, its thermal baths, archeological artifacts from the Iron Gates area, the medieval life in Turnu Severin, the correspondence of Bishop Calinic of Râmnicu, travel notes from Gorj county, the cultural life of Turnu Severin and the intellectual movement Casa Luminii, the biography of I.G. Bibicescu and the library he founded. Also, indirectly, Al. Bărcăcilă made himself present in the magazine Arhivele Olteniei through a rich series of reviews of his scientific works, all published by C.D. Fortunescu. In short, Bărcăcilă was given the recognition he deserved by the magazine Arhivele Olteniei as a true scholar and historian.
Documente privind activitatea cultural-ştiinţifică a profesorului Ilie Constantinescu, colaborator al revistei „Arhivele Olteniei”
Authors:   Serviciul Județean Olt al Arhivelor Naționale, Preda Dana Iulia
Published: July 2023

Born in a humble family of peasants from Diosti village, Country Romanaţi (today Country Dolj), Ilie Constantinescu, romanian language and history professor at Ioniţă Asan High School from Caracal, between years 1906 and 1938 , was one of the biggest collector of ethnographical and archaeological material, historical documents and coins of our country. He also activated in scientifical field, being contributor of Arhivele Olteniei review at the beginnings of this publication, during the years 1923-1924, writting papers about the history of his birthplace Dioşti and about the cultural movement in Caracal from year 1923. In this paper, we will present several documents from years 1908-1933, stored in the documentary collection of Ioniţă Asan Lyceum from National Archives – Country Service Olt, which reflect the constant preoccupation of professor Ilie Constantinescu with gathering up important archeological and historical materials: old church icons and clothes, coins from roman perioade, a roman sarcophagus-covering from stone. Also, we are presenting documents concerning the foundation and the activity of the cultural and scientific society of Ioniţă Asan High School’s students called “Olteanul Voinic”, society founded in year 1913, due to professor Ilie Constantinescu’s labours.
Elements of the relations between Petru Cercel and the Romanian orthodox church
Authors:   Academia Oamenilor de Știință din Româna (AOSR), Vergatti Radu Ștefan
Published: July 2023

Petru Cercel (1583-1585), Prince of Wallachia, was a complex personality. Educated as a guarantor prince at the Sublime Porte where he had spent his entire childhood and the first part of his youth, he then travelled through most of Western Europe, in his Odyssey of obtaining the throne inherited from his father. Through his direct contact with France, and with the Italian States, he became a man of the Western Renaissance. He spoke 12 foreign languages fluently. He wrote poems with an Orthodox character. Among them, there is one published by Gr. Tocilescu, translated by Al. Ciorănescu, which was printed in Venice in 1586. He transposes these values in Wallachia, after he ascends to the throne. During his short rule, of less than two years, he radically changes the aspect of the Princely Court in Târgovişte. He builds a palace and a church with a cross-in-square layout, which is rare for the classical Wallachian architecture, he repairs and renovates and makes offerings to other monasteries and churches – the Metropolitan in Târgovişte, the Episcopal Church erected by Neagoe Basarab in Curtea de Argeş, the churches in Botuşari, Glavaciocul, Mislea, but also the St. Nicholas Church in Şcheii Braşovului. Thus, he placed himself on a higher level than his contemporaries. Due to the permanent fight for power and the pecuniary competition promoted by the circles of power within the Ottoman Empire, Petru Cercel perished in a tragical manner. He had a short existence, albeit an absolutely remarkable one, eulogistically remarked at the level of the most important powers of the era in Western Europe.
Terminologia frazeologică din domeniul vestimentației masculine
Authors:   Universitatea din București, Facultatea de Litere, TIRON RAREȘ
Published: July 2023

The phraseological terminology of the contemporary menswear is taken as the material of the present research. This article lists about 300 phraseological units in the field of men’s clothing analyzing some of their constant aspects such as etimology, penetration into Romanian, degree of determinologization, some situations of variation or phraseological synonymy, and occasionally, some stylistic remarks. The stake of this article is to briefly illustrate how a massive wave of loans assimilated in a short period of time can partially alter the code of a specialized language.
Correlation Between Acupuncture Point LI-18 and PC-1 Sensitivity and Front Hoof Surface Temperature in Horses Using Infrared Thermography
Authors: Dai Shu , Shiau Deng-Shan , Zilberschtein Jose
Published: July 2023

The objective of this study was to determine whether acupuncture point sensitivity to palpation at LI-18 and PC-1

acupoints in horses was correlated with a difference in surface temperature between front hooves measured by highresolution

infrared camera. Client-owned horses (n=41) presenting for traditional Chinese veterinary medicine (TCVM)

exams for a variety of medical issues were recruited for convenience sampling. After 20 minutes of stall rest, bilateral

front hoof thermography was performed in a designated stall. This was followed by bilateral acupoint scan (APS), where

the outcome was considered positive (APS+) when an acupoint palpation, performed with an acupuncture needle guide

tube (28 gauge, 2 inch), elicited a flinch response, or negative (APS-) when the palpation equaled no reaction. Based on the APS results, horses were grouped into 1) bilateral APS- outcome (bi-APS-) or 2) unilateral APS+ outcome (uni-APS+). Within each of the 2 groups mean temperature difference between front hoof surfaces was compared. The results showed that the bi-APS- group thermographic readings were not significantly different (p=0.551) between front hooves; however,

the hoof temperatures were significantly different from each other in the uni-APS+ group (p=0.039). Study findings suggest that a horse’s APS sensitivity at LI-18 and/or PC-1 are correlated with thermographic imaging temperature of the front hooves. Further investigation and confirmation of these findings is needed along with further studies associating this temperature difference with hoof disorders for diagnostic investigations.
"He Grows Kind": Reimagining Community in Shakespeare's The Merchant of Venice
Authors: Huh Joanna
Published: July 2023

abstract: This essay takes up the question of community in William Shakespeare's The Merchant of Venice (ca. 1600) to explore alternative models that challenge the violently homogenizing and xenophobic society of Christian Venice. Through Antonio and Shylock's bond-of-flesh, the play invites audiences to witness the genesis and development of a new mode of interrelationality, evoked by the melancholic condition, propelled by desire for violence, and ensured through risking death. Drawing from Georges Bataille's "law," which insists that human beings are only united to each other through rents and wounds, this article details the way that The Merchant of Venice mobilizes an imaginative possibility whereby damage and vulnerability constitute communion. Contrasting such communion with Venetian sociality, this essay identifies the paradox that sociality—premised as it is on the protection of integral, bounded selves and undergirded by the ideology of possessive individualism—disallows the union for which sacrificial communion strives. Unexpectedly, the destruction and self-abnegation expressed by both Antonio and Shylock catalyze a costly and crucial rethinking of community, one that privileges risk and loss over the rational self-preservation essential to the Christian republican view of community.
Die demographische Situation in der Tschechischen Republik
Authors: Andrle Alois
Published: July 2023

Die politischen und ökonomischen Probleme der Tschechischen Republik erregen die volle Aufmerksamkeit der Politiker, Ökonomen wie auch der breiteren Öffentlichkeit. Im Hintergrund bleibt bisher die demographische Situation des Staates, die in den Ergebnissen der Volks‑, Häuser- und Wohnungszählung im März 1991 dokumentiert wurde. Dabei sind jedoch die Beziehungen aller erwähnten Phänomene historisch so eng, daß es trotz der nicht existierenden offiziellen tschechischen Bevölkerungspolitik zweckmäßig erscheint, sich mit ihnen zu befassen.Der Beitrag befaßt sich mit den wichtigsten Fragen der Bevölkerungsentwicklung in der Tschechischen Republik, die nicht nur für die Gegenwart charakteristisch sind, sondern auch die Bedingungen der weiteren Entwicklung beeinflussen, und das sicherlich bis zum Ende dieses Jahrhunderts und im Prinzip auch für die nachfolgenden Jahrzehnte.
ESTIMATION OF EXTREME WAVE CONDITIONS IN THE SOUTHERN NHA TRANG BAY AREA
Authors: Mau Le Dinh
Published: July 2023

This paper presents the distribution features of calculated maximum significant wave height in the Southern Nha Trang bay area corresponding to maximum wind speed of 50 years return periods.  Wind data from 1976 to 2006 were taken from Nha Trang Meteorological Station. Weibull  distrihution function was used to estimate maximum wind speed for different return periods.  Dolphin and SWAN models were used to estimate wave characteristics in the offshore and nearshore regions, respectively. The studied results show that maximum wind speeds for 50 years return period were 27, 22, 15 and 17 m/s in NE, E, SE and S directions, respectively. The areas of Southern Tre Island including Nha Trang Port, Mieu, Mot, Tam and Mun islands were strongest  affected by wave action from E and S directions with significant wave height of 2 - 4 m, and lesser affected by wave action from NE and SE directions with significant wave height  of 2 m. The area  between Mun Island to Noi and Ngoai Islands, and the coastline from Dong Ba to Cam Ranh  Headlands were strongest affected by wave action from E and NE directions with significant wave height of 4 - 7 m, and lesser affected by wave action from SE and S directions with significant wave height of 2 - 3 m. Maximum wind field blown from SW direction (V = 19 m/s) was generated a relatively strong wave field in the studv area, especialy in the area around Mun and Mot Islands  with significant wave height range from  1.5 to 2.0 m. In general, for maximum wind speed of 50 years return period the southern area of Nha Trang bay was strongest affected by wave action from  E and NE directions.
Thông tin khoa học:
Authors: Thanh Tran Duc
Published: July 2023

Hội nghị khoa học Thái Bình Dương giữa kỳ lần thứ 11
Changes in inflammatory responses and autophagy during apheresis platelet preservation and its correlation with platelet transfusion refractoriness in patients with acute lymphoblastic leukemia
Authors: Li Ying , Song Zhiqun , Sun Xiaohong , Tang Juanjuan , Zhou Xiaoyu
Published: July 2023

Acute lymphoblastic leukemia (ALL) is a common hematopoietic malignancy, and platelet transfusion plays a crucial role in its treatment. This study aimed to investigate the changes in inflammatory response and autophagy during the preservation of apheresis platelets (AP) and their correlation with platelet transfusion refractoriness (PTR) in ALL. ALL patients were included, and APs were categorized based on the preservation period (day 0, day 1, days 2-3, and days 4-5). The activation factors procaspase-activating compound 1 (PAC-1) and P-selectin (CD62P), AP aggregation function, inflammation levels (interleukin 1 beta [IL-1β], interleukin 6 [IL-6], tumor necrosis factor alpha [TNF-α] and NOD-like receptor thermal protein domain associated protein 3 [NLRP3]), and autophagy-related genes (p62) during AP preservation were assessed. Following co-culturing APs with peripheral blood mononuclear cells (PBMCs), specific activation markers were studied to observe APs influence on immune cells activation. The effectiveness of platelet transfusion was assessed, and risk factors for PTR were analyzed. As the storage duration of AP increased, the activation factors, coagulation factor activity, inflammation levels, and the activation of immune cells in AP increased, while fibrinogen levels and AP aggregation function decreased. The expression levels of autophagy-related genes (the autophagy marker light chain 3B gene [LC3B], and Beclin 1 gene) decreased with prolongation preservation. The effective rate of AP transfusion in ALL patients was 68.21%. AP preservation time, IL-6, p62, and Beclin 1 were identified as independent risk factors affecting PTR in ALL patients. In conclusion, during AP preservation, inflammation, autophagy, and activation of immune cells were observed to increase. AP preservation time, IL-6, p62, and Beclin 1 were independent risk factors for PTR.
Лечебная физическая культура при сколиозе
Authors: Бекетова И.В. , Проскурина Е.Ф.
Published: July 2023

В статье рассматриваются роль и особенности лечебной физической культуры для людей, имеющих сколиоз.
Experiences of professional nurses regarding shortage of resources at a tertiary hospital in Gauteng Province, South Africa: qualitative study
Authors: Jiyane Makoasha Philistus , Khunou Sisinyana Hannah
Published: July 2023

Background: Shortage of resources in hospitals is a global problem with South Africa not being excluded. These leads to a situation where most health care workers especially professional nurses (PNs)  leave the health institutions to private hospitals or abroad for better opportunities. The study explored and described professional nurses’ experiences regarding shortage of resources at a tertiary hospital in Gauteng Province.
Methods: Qualitative, explorative, descriptive design was used on a sample of 16 professional nurses (PNs), who have worked for two or more years in selected units. Unstructured individual conversations with a grand tour question were used. Tesch’s method was employed to analyze data.
Results: The study revealed both negative and positive experiences regarding the deficiency of resources. PNs experienced the following: The study revealed four themes: 1) Experiences pertaining to lack of material resources; 2)Negative impact of a shortage of resources on patients; 3) Experiences on inadequate number of nurses and support staff; 4) Dealing with a shortage of resources
Conclusions: Appropriate measures should be put in place to ensure that resources are adequate at this tertiary hospital. Medical machinery should be audited monthly and a daily checklist used to document available stock. Appropriate recruitment and retention policies must be implemented by the Human Resource Department to ensure that vacant posts are filled timeously and reduce high staff turnover. Perceptions of patients could be explored related to the unavailability of medicine in healthcare facilities