bluuebunny/crossref_metadata_2025 huggingface dataset:
The association of sialic acid levels with nitric oxide and C-reactive protein in patients with diabetic foot ulcer / Diyabetik ayak ülseri olan hastalarda sialik asit düzeylerinin nitrik oksit ve C-reaktif protein ile ilişkisi
Authors: Keti Didem Barlak , Muhtaroğlu Sabahattin , Ünlühızarcı Kürşad , Çetin İhsan
Published: August 2016

Objective: The present study aimed to evaluate the association of serum sialic acid (SA) levels with nitric oxide (NO) and C-reactive protein (CRP) in patients with diabetic foot ulcer.

Methods: This study included total 56 type 2 diabetic patients (27 of them had diabetic foot ulcer and 29 without it) and 22 healthy volunteers. Serum SA, NO and CRP levels were measured with spectrophotometric and nephelometric methods respectively.

Results: Serum SA levels were higher in diabetic foot group than diabetes group (p<0.05). CRP and NO levels were found to be significantly higher in diabetic foot group compared to the diabetes (p<0.001 and p=0.002, respectively) and control groups (p<0.001, both). Although there was no correlation between SA and NO (p>0.05), serum SA levels were significantly correlated with CRP in diabetic foot group (p<0.001).

Conclusion: We suggest that SA could be related to acute phase response in patients with diabetic foot ulcer. Elevated serum SA and NO levels may be indicators of oxidative stress-induced vascular damage.
Effects of jinggangmycin on peroxidase and esterase isozymes and phytotoxin from Rhizoctonia solani AG-1 IA, the causal agent of rice sheath blight. Pirinç kabuğu yanığı nedeni Rhizoctonia solani AG-1 IA tarafından üretilen peroksidaz, esteraz izozimleri ve fitotoksinler üzerinde jinggangmycin etkisi
Authors: Yang Ying-Qing , Li Ming-Hai , Yang Mei , Shu Can-Wei , Li Xiang-Min , Lan Bo , Jian Yan-Li , Zhou Er-Xun
Published: August 2016

Objective: To explore the effects of jinggangmycin on the pathogenicity of rice sheath blight.

Methods: The effects of jinggangmycin on peroxidase and esterase isozymes from Rhizoctonia solani Kuhn AG-1 IA were compared using non-denaturing polyacrylamide gel electrophoresis (PAGE). Rs-toxins were obtained from the improved Richard medium amended with jinggangmycin at different concentrations. Subsequently, bioassays of Rs-toxin, including virulence to rice tissues, seedling wilting and inhibition to the seed germination were conducted.

Results: The results of PAGE showed that when the jinggangmycin concentration increased to 50 μg/mL, two of peroxidase isozyme bands became apparently weaker compared with the controls, indicating that jinggangmycin could considerably weaken the activity of the peroxidase isozyme. In addition, three extra bands of esterase isozyme were induced by jinggangmycin when the concentration increased to 50 μg/mL, indicating that jinggangmycin could affect the metabolism of esterase isozyme. The bioassays of Rs-toxin showed that jinggangmycin could weaken the virulence of Rs-toxin in rice tissues.

Conclusion: It was concluded that the control role of jinggangmycin in rice sheath blight might be due to the effects of jinggangmycin on the peroxidase and esterase isozymes and Rs-toxin virulence.
The role of syncytins in human reproduction and reproductive organ cancers
Authors: Soygur Bikem , Sati Leyla
Published: August 2016

Human life begins with sperm and oocyte fusion. After fertilization, various fusion events occur during human embryogenesis and morphogenesis. For example, the fusion of trophoblastic cells constitutes a key process for normal placental development. Fusion in the placenta is facilitated by syncytin 1 and syncytin 2. These syncytins arose from retroviral sequences that entered the primate genome 25 million and more than 40 million years ago respectively. About 8% of the human genome consists of similar human endogenous retroviral (HERVs) sequences. Many are inactive because of mutations or deletions. However, the role of the few that remain transcriptionally active has not been fully elucidated. Syncytin proteins maintain cell–cell fusogenic activity based onenvgene-mediated viral cell entry. In this review, we summarize how syncytins and their receptors are involved in fusion events during human reproduction. The significance of syncytins in tumorigenesis is also discussed.
Uterine flushing proteome of the tammar wallaby after reactivation from diapause
Authors: Martin Florine C , Ang Ching-Seng , Gardner David K , Renfree Marilyn B , Shaw Geoff
Published: August 2016

The marsupial tammar wallaby has the longest period of embryonic diapause of any mammal, up to 11 months, during which there is no cell division or blastocyst growth. Since the blastocyst in diapause is surrounded by acellular coats, the signals that maintain or terminate diapause involve factors that reside in uterine secretions. The nature of such factors remains to be resolved. In this study, uterine flushings (UFs) were used to assess changes in uterine secretions of tammars using liquid chromatography–mass spectrometry (LC–MS/MS) during diapause (day 0 and 3) and reactivation days (d) 4, 5, 6, 8, 9, 11 and 24 after removal of pouch young (RPY), which initiates embryonic development. This study supports earlier suggestions that the presence of specific factors stimulate reactivation, early embryonic growth and cell proliferation. A mitogen, hepatoma-derived growth factor and soluble epidermal growth factor receptors were observed from d3 until at least d11 RPY when these secreted proteins constituted 21% of the UF proteome. Binding of these factors to specific cellular receptors or growth factors may directly stimulate DNA synthesis and division in endometrial gland cells. Proteins involved in the p53/CDKN1A (p21) cell cycle inhibition pathway were also observed in the diapause samples. Progesterone and most of the oestrogen-regulated proteins were present in the UF after d3, which is concomitant with the start of blastocyst mitoses at d4. We propose that once the p21 inhibition of the cell cycle is lost, growth factors including HDGF and EGFR are responsible for reactivation of the diapausing blastocyst via the uterine secretions.
Nickel‐smelting fumes increased the expression of HIF‐1α through PI3K/ERK pathway in NIH/3T3 cells
Authors: Han Dan , Yang Yue , Zhang Lin , Wang Chao , Wang Yue , Tan Wen‐Qiao , Hu Xue‐Ying , Wu Yong‐Hui
Published: August 2016

Objective

The purpose of this study was to investigate the effects of Nickel (Ni)‐smelting fumes on oncogenic proteins in vivo and in vitro.

Methods

Ni fallout beside a Ni smelting furnace in a factory was sampled to study its toxic effect. The effects of Ni‐smelting fumes on the regulation of PI3K and ERK signaling pathways and the important downstream hypoxia inducible factor, HIF‐1α, were studied both in NIH/3T3 cells and in the lung tissue of rats. NIH/3T3 cell transformation induced by Ni‐smelting fumes was also observed.

Results

Ni‐smelting fumes activated PI3K, p‐AKT, p70S6K 1, and ERK proteins and increased HIF‐1α expression in a time‐and dose‐dependent manner. However, activation was suppressed when NIH / 3 T 3 cells were pretreated with PI 3 K / AKT or ERK inhibitors. Ni‐smelting fumes caused malignant transformation of NIH/3T3 cells.

Conclusions

Ni‐smelting fumes increased the expression of HIF‐1α through the PI3K/ERK pathway in NIH/ 3T3 cells and induced malignant transformation in these cells indicating that Ni‐smelting fumes may be a potential carcinogen in mammalian cells.
Investigation of rare chronic lipoid pneumonia associated with occupational exposure to paraffin aerosol
Authors: Han Chenghong , Liu Lihai , Du Shiping , Mei Jianhua , Huang Ling , Chen Min , Lei Yongliang , Qian Junwen , Luo Jianyong , Zhang Meibian
Published: August 2016

Objectives

Occupational exposure to paraffin is an infrequent cause of lipoid pneumonia (LP) and related data are scare. We investigated the possible relationship between three rare cases of chronic LP and occupational exposure to paraffin aerosol in an iron foundry.

Methods

The three cases of LP and their workplaces were investigated using data from field investigations, air monitoring, pulmonary radiological examinations, cell staining, and lung biopsies.

Results

The patients had long‐term occupational exposure to paraffin. X‐ray diffraction testing revealed that the raw material from the workshop was paraffin crystal. The air concentrations of paraffin aerosol in workplaces were significantly higher than outdoor background levels. Small diffuse and miliary shadows with unclear edges were observed throughout the whole lungs via radiography. Computed tomography revealed diffuse punctate nodules and a high density of stripe‐like shadows in both lungs (ground‐glass opacity in a lower lobe, and a masslike lesion and high translucent area near the bottom of the lung). Lipid‐laden macrophages were found in the sputum and bronchial lavage. A broadened alveolar septum and local focal fibrosis were also discovered via lung biopsy. The inflammatory reaction in the lung tissues appeared to resolve over time.

Conclusions

These three rare cases of chronic LP in workers during molding and repair processes were associated with occupational paraffin aerosol exposure. Therefore, primary prevention is essential for molding or repairing workers in the iron foundry, and a differential diagnosis of occupational chronic LP (vs. pneumoconiosis) should be considered when treating these workers.
Health Care Maintenance for the Pediatric Patient With Inflammatory Bowel Disease
Authors: DeFilippis Ersilia M. , Sockolow Robbyn , Barfield Elaine
Published: August 2016

Nearly one-quarter of patients with inflammatory bowel disease (IBD) are younger than 20 years of age at diagnosis. Furthermore, the incidence of IBD in children continues to increase. Nevertheless, variation in management exists within the care of patients with IBD with regards to disease screening and preventive care. A multidisciplinary approach that involves the general practitioner and pediatric gastroenterologist is needed to routinely monitor growth, bone health, vitamin and mineral deficiencies, vaccination status, and endoscopic surveillance. It is also important to monitor for extraintestinal manifestations of IBD that may affect the liver, joints, skin, and eyes. The purpose of this article is to provide an updated overview of comprehensive care for pediatric patients with IBD.
Stronger and More Vulnerable: A Balanced View of the Impacts of the NICU Experience on Parents
Authors: Janvier Annie , Lantos John , Aschner Judy , Barrington Keith , Batton Beau , Batton Daniel , Berg Siri Fuglem , Carter Brian , Campbell Deborah , Cohn Felicia , Lyerly Anne Drapkin , Ellsbury Dan , Fanaroff Avroy , Fanaroff Jonathan , Fanaroff Kristy , Gravel Sophie , Haward Marlyse , Kutzsche Stefan , Marlow Neil , Montello Martha , Maitre Nathalie , Morris Joshua T. , Paulsen Odd G. , Prentice Trisha , Spitzer Alan R.
Published: August 2016

For parents, the experience of having an infant in the NICU is often psychologically traumatic. No parent can be fully prepared for the extreme stress and range of emotions of caring for a critically ill newborn. As health care providers familiar with the NICU, we thought that we understood the impact of the NICU on parents. But we were not prepared to see the children in our own families as NICU patients. Here are some of the lessons our NICU experience has taught us. We offer these lessons in the hope of helping health professionals consider a balanced view of the NICU’s impact on families.
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Authors: Periódicos EDIPUCRS
Published: August 2016

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A revised and updated checklist of Monogononta rotifers from Argentina
Authors: Ferrando Noelia S. , Claps María C.
Published: August 2016

We provide here a checklist of species of Monogononta rotifers from lentic and lotic environments in Argentina, 25 years after the initial catalogue compiled by Susana B. José de Paggi. This new inventory now includes the reports on rotifers documented in 93 studies produced after 1990. The majority of the investigations were carried out in three of the 24 Argentine provinces. In addition, the presence of 13 species in samples from three water bodies within Buenos Aires province are now cited here for the first time in Argentina. In this updated checklist, a total of 351 species are catalogued, the majority being representatives of the Lecanidae, Brachionidae, and Lepadellidae.
O processo de comunicação na Telenfermagem: revisão integrativa
Authors: Barbosa Ingrid de Almeida , Silva Karen Cristina da Conceição Dias da , Silva Vladimir Araújo da , Silva Maria Júlia Paes da
Published: August 2016

RESUMO Objetivo: identificar as evidências científicas sobre o processo de comunicação na Telenfermagem e analisá-las. Método: revisão integrativa, realizada em março de 2014. A estratégia de busca, estruturada com os descritores "telenfermagem" e "comunicação", foi implementada nas bases de dados Medline, Bireme, Cinahl, Scopus, Web of Science, Scielo e Cochrane. Resultados: ao serem aplicados critérios de inclusão e exclusão, selecionaram-se 10 estudos. Os principais desafios ponderados foram: a condição clínica dos pacientes, a possibilidade de que comunicação inadequada gere erros de conduta, a ausência de referências visuais em interações sem recurso de vídeo, e dificuldade de compreensão do não verbal. Conclusão: a distância impõe barreiras comunicativas em todos os elementos: emissor, receptor e mensagem; e em ambas as maneiras de transmissão, verbal e não verbal. A principal dificuldade é compreender o não verbal. Para cuidar adequadamente neste contexto, o enfermeiro deve receber formação específica, para que desenvolva competências e habilidades comunicacionais.
AVOCADO SEEDLINGS MULTIPLE STEMS PRODUCTION
Authors: PAIXÃO MARCUS VINICIUS SANDOVAL , LOPES JOSÉ CARLOS , SCHMILDT EDILSON ROMAIS , ALEXANDRE RODRIGO SOBREIRA , MENEGHELLI CAROLINE MERLO
Published: August 2016

ABSTRACT This study aimed to evaluate the potential of multi-stems in avocado seeds according to their mass as well as the adventitious rooting of multi-stem budding with or without the use of auxin. The research was carried out at the Vegetation House of Federal Institute of Espírito Santo, Campus Santa Teresa -ES, with seeds of different masses: <60 g, 61 to 80 g, 81 to 100 g and >100 g, in which each experimental unit was made of five seeds, distributed within five repetitions, under a completely randomized design. The seeds were put to germinate and the percentage number of emergence and multiple stems were evaluated. After 150 days, the following evaluations were carried out: survival of rooted cuttings; number of leaves; stem diameter; root length; root volume; root and shoot fresh mass; root and shoot dry mass; shoot height; absolute growth and shoot growth rate; shoot dry weight/root dry mass ratio; shoot height/stem diameter ratio; shoot height/root length and Dickson's quality index ratio. Avocado seeds with mass over 100 g and between 81-100 g presented higher percentage of multiple stems. Rods over 20 cm that were not treated with IBA (indole-3-butyric acid) resulted on avocado plants of better quality. The use of IBA (2000 mg L-1) does not affect the rooting and growth of avocado's multi-stem plants.
Healthy gestational weight gain prevalence and associated risk factors: A population-based study in the far South of Brazil
Authors: MARMITT Luana Patricia , GONÇALVES Carla Vitola , CESAR Juraci Almeida
Published: August 2016

ABSTRACT Objective To measure and identify the factors associated with healthy weight gain during pregnancy in the municipality of Rio Grande, Rio Grande do Sul, Brazil. Methods This was a population-based, cross-sectional study that included all parturient women from the municipality who gave birth at its maternity hospitals in 2013. Information was collected by interview with the mothers in the first 48 hours following parturition and from the prenatal care cards. Healthy weight gain was evaluated according to the Institute of Medicine guidelines. Data analysis used Poisson regression with robust variance using previous hierarchical model. Results Among the 1,784 pregnant participants, 89% attended at least six prenatal care visits, and 32% had healthy weight gain during pregnancy. Higher education level and fewer children resulted in a higher prevalence ratio for healthy weight gain (p=0.003 and p=0.029, respectively). Underweight women at conception had a higher proportion of healthy weight gain (p<0.001). Despite extensive coverage, prenatal care did not affect healthy weight gain during pregnancy (p=0.104). Conclusion The low proportion of women with healthy gestational weight gain suggests a need of better prenatal care services. Women who are overweight, have lower education levels, and had had multiple pregnancies at conception need special attention.
Estado nutricional em vitamina A de puérperas adolescentes e adultas assistidas em maternidade pública
Authors: GURGEL Cristiane Santos Sânzio , OLIVEIRA Priscila Gomes de , ASSUNÇÃO Débora Gabriela Fernandes , DAMETTO Juliana Fernandes dos Santos , DIMENSTEIN Roberto
Published: August 2016

RESUMO Objetivo Avaliar o estado nutricional em vitamina A de puérperas adolescentes e adultas em relação à ingestão alimentar, retinol no soro e colostro e o suprimento desta vitamina para o recém-nascido. Métodos Estudo transversal, incluindo 136 puérperas, sendo 68 adolescentes e 68 adultas, atendidas em uma maternidade pública. A ingestão dietética de vitamina A foi estimada por um questionário de frequência do consumo alimentar. Foram coletados sangue e colostro em condição de jejum para análise dos níveis de retinol. As amostras foram analisadas por cromatografia líquida de alta eficiência. A estimativa da ingestão de vitamina A pelo recém-nascido foi calculada pelo volume ingerido de leite e a média da concentração de retinol no colostro materno. Resultados A estimativa de consumo foi 681,2±535 µgRAE/dia, para as adolescentes, e 891,8±831,5 µgRAE/dia, para as adultas (p>0,05). As médias de retinol sérico foram 40,6±9,7 µg/dL, no grupo das adolescentes, e 44,9±10,9 µg/dL, no das adultas (p<0,05). No colostro, as adolescentes apresentaram concentração de retinol de 83,1±26,5 µg/dL e as adultas de 81,8±29,8 µg/dL (p>0,05). O volume médio ingerido pelos lactentes provenientes de puérperas adolescentes foi de 435,1+140,7 µgRAE/dia e de 409,7+150,8 µgRAE/dia pelos recém-nascidos das adultas. Na análise individual, 42,6% (n=29) das adolescentes e 52,9% (n=36) das mães adultas não supriram adequadamente a recomendação diária do lactente. Conclusão As adolescentes apresentaram ingestão inadequada de vitamina A. Ambos os grupos apresentaram percentuais de inadequação no soro e colostro e, consequentemente, no fornecimento da vitamina A aos recém-nascidos.
Impacto da suplementação com ácidos graxos ômega-3 nas subfrações da lipoproteína de alta densidade de indivíduos tabagistas
Authors: PAPPIANI Caroline , DAMASCENO Nágila Raquel Teixeira
Published: August 2016

RESUMO Objetivo Avaliar o efeito da suplementação com ômega-3 nas subfrações das lipoproteínas de alta densidade em indivíduos tabagistas. Métodos Ensaio clínico, randomizado, duplo-cego. Foi selecionada uma amostra com 33 tabagistas, de ambos os sexos, com idade entre 30 e 60 anos, suplementados com ômega-3 (n=17) ou placebo (ácidos graxos ômega-6, n=16) por dois meses. As subfrações das lipoproteínas de alta densidade foram analisadas pelo sistema Lipoprint. Os testes estatísticos foram realizados com o auxílio do programa Statistical Package for the Social Sciences, versão 20.0. Resultados A média de idade foi 49 anos, com predominância da raça branca. Após a intervenção, o grupo ômega-3 modificou positivamente o perfil lipídico e as subfrações das lipoproteínas de alta densidade dos tabagistas. Nos modelos de regressão linear testados, o percentual de ácido docosahexaenoico plasmático apresentou associações negativas com o percentual das lipoproteínas de alta densidade-pequena. Conclusão A suplementação com ômega-3 está associada a uma alteração favorável na distribuição das subfrações das lipoproteínas de alta densidade, aumentando as lipoproteínas de alta densidade-grande e diminuindo as lipoproteínas de alta densidade-pequena. Isso reforça a importância do ômega-3 na saúde cardiovascular de indivíduos tabagistas.
Excesso de peso e ambiente de trabalho no setor público municipal
Authors: FREITAS Patrícia Pinheiro de , ASSUNÇÃO Ada Ávila , BASSI Iara Barreto , LOPES Aline Cristine Souza
Published: August 2016

RESUMO Objetivo: Identificar se características sociodemográficas, hábitos alimentares, situação de saúde e condições de trabalho estão relacionadas ao excesso de peso em servidores e empregados públicos municipais. Métodos: Inquérito epidemiológico eletrônico (online) com servidores do município de Belo Horizonte, Minas Gerais, de setembro a dezembro de 2009. Investigaram-se informações sociodemográficas, de saúde, hábitos relacionados à alimentação e nutrição e informações sobre condições e ambiente de trabalho. Foi realizada análise de Regressão de Poisson (p<0,05), ajustada por sexo, idade e tempo do funcionário na função. Resultados: Um total de 44,4% dos participantes (n=4.893) apresentou sobrepeso, que prevaleceu em mulheres (p<0,001) e pessoas com maior mediana de idade (p<0,001), com filhos (p<0,001), casadas ou em união estável (p=0,002), e com menor nível educacional (p<0,001) e status ocupacional (p<0,001), determinados pelo International Socio-Economic Index. A regressão de Poisson encontrou associação entre sobrepeso e auto-relato de diabetes mellitus (RP=1,15; IC95%=1,03-1,27), hipercolesterolemia (RP=1,24; IC95%=1,15-1,32), hipertensão arterial (RP=1,47; IC95%=1,37-1,58), autoavaliação de saúde (RP=1,20; IC95%=1,12-1,29), cozinhar habitualmente (RP=1,11; IC95%CI=1,04-1,20), consumir carne com gordura aparente (RP=1,16; IC95%=1,08-1,24), e frequentemente não pausar durante o trabalho (RP=1,10; IC95%=1,03-1,18). Conclusão: A relação entre ambiente de trabalho e excesso de peso, evidenciada pela associação com a privação de pausa no trabalho, denota a necessidade de medidas preventivas específicas que considerem as características do ambiente de trabalho.
Influência de intervenções educativas em perfis antropométricos, clínicos e bioquímicos e na percepção de saúde e doença de portadores de hipertensão arterial no contexto da Saúde da Família
Authors: EINLOFT Ariadne Barbosa do Nascimento , SILVA Luciana Saraiva da , MACHADO Juliana Costa , COTTA Rosângela Minardi Mitre
Published: August 2016

RESUMO Objetivo: Analisar a influência de intervenções educativas nos perfis antropométricos, clínicos e bioquímicos, bem como na percepção de saúde e doença de portadores de hipertensão arterial sistêmica no contexto da Estratégia de Saúde da Família. Métodos: Estudo longitudinal, de intervenção e comparativo, realizado com portadores de hipertensão arterial sistêmica cadastrados e acompanhados pela Estratégia de Saúde da Família do município de Porto Firme, Minas Gerais, Brasil. Realizaram-se intervenções educativas, com duração de 12 meses, nas unidades de Estratégia de Saúde da Família e durante visitas domiciliárias. Analisaram-se dados socioeconômicos, hábitos de vida, cuidados de saúde, nível de apreensão e conhecimento sobre a hipertensão arterial sistêmica, percepção de saúde e doença, além das variáveis antropométricas, bioquímicas e clínicas, antes e após as intervenções. Resultados: Ainda que de forma discreta, foi possível perceber melhorias nas avaliações clínicas, bioquímicas e antropométricas. As variáveis índice de massa corporal (p=0,001), circunferência da cintura (p<0,001), glicose (p=0,011), colesterol total (p<0,001), lipoproteínas de alta densidade colesterol (p<0,001) e triglicerídeos (p=0,019) apresentaram diferenças estatisticamente significativas antes e após as intervenções. Os entrevistados mostraram incorporação de novos conhecimentos ao significado da hipertensão arterial sistêmica e a percepção de saúde e doença relacionou-se de forma mais importante com aspectos subjetivos da experiência vivencial e com a qualidade de vida em detrimento das questões biológicas e médicas. Conclusão: As intervenções educativas demonstraram importante potencial no enfrentamento da hipertensão arterial sistêmica ao promoverem alterações positivas nos perfis analisados; contudo, seu efeito tem forte relação com a continuidade das ações.
Combined effects of resistance training and carbohydrate-restrictive or conventional diets on weight loss, blood variables and endothelium function
Authors: MEIRELLES Claudia Mello , GOMES Paulo Sergio Chagas
Published: August 2016

ABSTRACT Objective: To compare the effects of either a carbohydrate-restrictive diets or a conventional hypoenergetic diet combined with resistance training. Methods: Twenty-one overweight and obese adults participated in an eight-week program consisting of progressive resistance training combined with carbohydrate-restrictive diets (initially set at <30 g carbohydrate; n=12) or conventional hypoenergetic diet (30% energetic restriction; carbohydrate/protein/lipid: 51/18/31% of total energy consumption; n=9). It was hypothesized that the carbohydrate-restrictive diets would induce greater weight loss but that both diets would elicit similar effects on selected health markers. Body mass, and body composition, blood variables and flow-mediated brachial artery dilation (flow-mediated brachial artery dilation; by ultrasound) were used to assess changes due to the interventions. Results: Significant within-group reductions in body mass (-5.4±3.5%; p=0.001 versus -3.7±3.0%; p=0.015) and body fat (body fat; -10.2±7.0%; p=0.005 versus -9.6±8.8%; p=0.017) were identified for carbohydrate-restrictive diets and conventional hypoenergetic diet, respectively, but there were no significant differences between groups as the result of the interventions. Fat free mass, blood variables and flow-mediated brachial artery dilation did not significantly change, except for the total cholesterol/high-density lipoprotein ratio, which was reduced 10.4±16.9% in carbohydrate-restrictive diets (p=0.037) and 0.5±11.3% in conventional hypoenergetic diet (p=0.398). Conclusion: Carbohydrate-restrictive diets associated with resistance training was as effective as conventional hypoenergetic diet in decreasing body mass and body fat, as well as maintaining fat free mass, blood variables and flow-mediated brachial artery dilation, however it was more effective at lowering the total cholesterol/low density lipoprotein ratio.
Counseling and oral splint for conservative treatment of temporomandibular dysfunction: preliminary study
Authors: MARTINS Ana Paula Varela Brown , AQUINO Luana Maria Martins de , MELOTO Carolina Beraldo , BARBOSA Célia Marisa Rizzatti
Published: August 2016

Abstract Introduction Temporoamndiular Disorders (TMD) involve the masticatory muscles, temporomandibular joint (TMJ) or both. The most common symptom is pain, which is usually located in the muscles of mastication, pre-auricular region, and / or ATM, especially during mandibular function. The main treatment for TMD is related to pain relief. Objective The purpose of this case report was to evaluate the reduction of pain symptoms using Visual Analogue Scale (VAS) of patients with TMD treated with counseling and use of occlusal splint (OS). Material and method 16 subjects had participated in this study, that was composed by 4 appointment with 7-day interval between each (CEP FOP / Unicamp – 137/2009). In the first, an examiner used the Research Diagnostic Criteria for Temporomandibular Disorders (RDC / TMD) to diagnose each patient and delivered a VAS to register the intensity of daily pain. In the second, counseling, molding of both dental arcs to fabricate the OS and the delivery of new VAS were performed. In the third, there was the installation and adjustment of the OS and the delivery of another scale, and in the last, possible adjustments on the OS were done. Data were analyzed by ANOVA two way and Tukey post-test at 5% significance level. Result There was significant difference when comparing the intensity of pain of individuals after installation of splint with the baseline data and after counseling (p = 0.05). Conclusion According to the result of this study, the treatment of TMD associating counseling occlusal splint is effective in reducing pain intensity.
PINGA-FOGO COM CHICO XAVIER: DO ETHOS À SEMÂNTICA GLOBAL DO DISCURSO ESPÍRITA KARDECISTA
Authors: Silva Tamiris Vianna da , Brunelli Anna Flora
Published: August 2016

Resumo Considerando as reflexões desenvolvidas por Maingueneau (2001, 2005, 2006, 2008) sobre a noção de ethos discursivo, analisa-se, neste trabalho, o ethos do médium Francisco Cândido Xavier na obra Pinga-Fogo com Chico Xavier, com o intuito de contribuir com os estudos sobre o discurso espírita kardecista, um dos discursos religiosos que há no Brasil. Para tanto, observa-se especialmente o léxico de ocorrências relativas ao ethos pré-discursivo, ao ethos dito e ao ethos mostrado, o que permite identificar não só o perfil do fiador do discurso, mas também a cena de enunciação em que esse fiador emerge. Por fim, demonstra-se como o ethos do médium está vinculado à semântica global do discurso espírita kardecista.
LE DISCOURS POLITIQUE DE DILMA ROUSSEFF ET LES FANTOMES DE LULA: ETUDE SUR L'INTERSUBJECTIVITE DANS LA POLITIQUE
Authors: Castro Fábio Fonseca de
Published: August 2016

Résumé L'article analyse l'ensemble discursif de la première année de communication publique de Dilma Rousseff en tant que présidente du Brésil (2011) cherchant à comprendre comment a été produit l'agencement entre la nouvelle présidente et l'ancien, Lula, en tant que procès discursif de construction et validation d'un pouvoir. En d'autres termes, comment fut construite la persona politique de Dilma tout en agençant celle de Lula ? Nous travaillons ce processus en termes de médiation intersubjective, essayant de comprendre cet ensemble composite d'agentivités, dont Lula, le PT et les causes de la gauche brésilienne apparaissent avec plus ou moins de clarté selon le contexte donné et selon la nécessité et la possibilité de mettre en évidence cette nouvelle persona politique. Pour ce faire, nous observons cet espace d'interstices, cette dimension pré-discursive, intersubjective, dans laquelle s'est produit ce phénomène que Derrida comprend comme l'indécidable et qui caractérise la dimension présymbolique et pré-compréhensive du processus social.
O EFEITO SUJEITO-DISCENTE E O EFEITO SUJEITO-DOCENTE NO DISCURSO DO DADEB: BREVE ANÁLISE DISCURSIVA SOB A PERSPECTIVA DA SUSTENTABILIDADE
Authors: Santos Janete Silva dos , Gonçalves Sheila de Carvalho Pereira , Andrade Karyleilla dos Santos
Published: August 2016

Resumo Este artigo, apoiando-se em pressupostos teórico-metodológicos da Análise do Discurso de linha francesa, analisa certos efeitos do discurso que apela à reconfiguração identitária de sujeitos no âmbito educacional, focando especificamente o Ensino Médio e mobilizando, nesse contexto, discursos de sustentabilidade, conforme Hargreaves e Fink. O corpus da investigação constitui-se de excertos do documento Direito à aprendizagem e ao desenvolvimento na educação básica (DADEB), produzido pelo Ministério da Educação (MEC). Os resultados da reflexão apontam o esforço, mediante estratégia discursiva, de apagamento dos conflitos que inevitavelmente perpassam a reconfiguração identitária projetada no referido documento, visto que, ao propor um novo perfil para o sujeito-discente, não deixa de instaurar a necessidade de reconfiguração do perfil do sujeito-docente, silenciando, porém, os entraves para essa desejada reconstrução identitária.
Analysis of the Psychometric Properties of a Parental Alienation Scale
Authors: Gomide Paula Inez Cunha , Camargo Everline Bedin , Fernandes Marcia Gonzales
Published: August 2016

Abstract The development of forensic evaluation scales is fundamental. This study's purpose was to explore the psychometric properties of a parental alienation scale. Forensic technicians completed 193 scales concerning parents involved in a lawsuit: 48 families with at least one parent indicated as the alienator (group A) and 48 families with no parental alienation claim (group B). The scale consisted of five categories and 69 items: denying access to the child; derogatory comparisons; emotional manipulation; behavior of parent and child during assessment. The results show Cronbach's alpha = .965 and split-half = .745; KMO = .884 and Bartlett's sphericity test ( p < .001). Concurrent criterion validity applied to data showed that the scale is able to distinguish between the alienator and target parent. The results showed significant and consistent standards in the instrument's psychometric characteristics.
Validity Evidence for the Turnover and Attachment Motives Survey (TAMS) in a Brazilian Sample
Authors: Oliveira Manoela Ziebell de , Beria Francielle Machado , Gomes William Barbosa
Published: August 2016

Abstract Staff turnover has become a growing concern of organizational research, yelding many predictive models worldwide. One promising model is the Turnover and Attachment Motives Survey (TAMS). This study aimed to adapt and validate the TAMS to the Brazilian organizational context, and ensure that the universality claim of the theory remains true. Participants were 523 Brazilian professionals occupying a range of positions in diverse companies. Their ages ranged between 24 and 54 years (M = 34.2, SD = 7.17), and they were predominantly men (57.7%). Results provided evidence of internal consistency, convergent, divergent, and predictive validity, advocating on behalf of TAMS as a tool for more adequately understanding and managing turnover intention and its antecedents among employees. Despite being a promising measure, we suggest the necessity for further investigation and improvement, in future studies, of some of TAMS' subscales, such as normative and constituent forces.
A oferta da terapia fonoaudiológica em locais de assistência a indivíduos com Transtornos do Espectro do Autista (TEA)
Authors: Defense-Netrval Danielle Azarias , Fernandes Fernanda Dreux Miranda
Published: August 2016

RESUMO Os Transtornos do Espectro Autista (TEA) têm sido grande preocupação em saúde pública devido ao aumento de sua prevalência e isto traz à tona, a discussão sobre a assistência prestada assim como dos acompanhamentos terapêuticos necessários. Dentre estes acompanhamentos, se destaca a terapia fonoaudiológica. Este estudo buscou caracterizar a oferta desse serviço nos diversos locais de assistência a essa população no município de São Paulo e para isso, elaborou-se um questionário. Participaram do estudo 25 locais com um total de 854 indivíduos com TEA assistidos. Observou-se que apenas 64% dos locais oferecem o acompanhamento fonoaudiológico e que o número dos indivíduos com indicação para esse acompanhamento está aquém do esperado. Conclui-se que há necessidade de gerenciamento no serviço fonoaudiológico oferecido a esta população.
Aspectos da fluência em tarefa de narrativa oral na síndrome del22q11.2
Authors: Santos Amanda Oliveira , Rossi Natalia Freitas , Tandel Maria da Conceição Faria Freitas , Richieri-Costa Antonio , Giacheti Célia Maria
Published: August 2016

RESUMO Objetivo Investigar os aspectos da fluência em tarefa de narrativa oral na síndrome del22q11.2 e comparar com indivíduos com desenvolvimento típico de linguagem. Método Participaram deste estudo 15 indivíduos com diagnóstico da síndrome del22q11.2, de ambos os gêneros, com idade cronológica de sete a 17 anos, que foram comparados a 15 indivíduos com desenvolvimento típico de linguagem, semelhantes quanto ao gênero e à idade cronológica. A narrativa oral foi eliciada com o livro Frog Where Are You?, e os aspectos da fluência foram analisados quanto ao tipo e frequência de disfluência (comum e gaga) e velocidade de fala. Foram analisados também o número e a duração das pausas. Os achados foram analisados estatisticamente. Resultados O grupo com a síndrome del22q11.2 apresentou média superior em relação ao grupo sem a síndrome, para a porcentagem de disfluências comuns, principalmente hesitação e revisão. O grupo com a síndrome também apresentou média superior para disfluências gagas, sendo a pausa a disfluência mais frequente. Quanto à velocidade de fala, o grupo com a síndrome apresentou média inferior para o número de palavras e sílabas por minuto. Assim sendo, conclui-se que os indivíduos com a síndrome del22q11.2 apresentaram mais dificuldades para narrar do que os seus pares. Conclusão Os aspectos da fluência investigados foram semelhantes entre os grupo com a síndrome del22q11.2 e com desenvolvimento típico de linguagem quanto à presença de hesitação, revisão e pausa na narrativa oral, porém distinto quanto à frequência dessas disfluências, que foi superior para os indivíduos com a síndrome.
Evaluation in health: participatory methodology and involvement of municipal managers
Authors: Almeida Cristiane Andrea Locatelli de , Tanaka Oswaldo Yoshimi
Published: August 2016

ABSTRACT OBJECTIVE To analyze scopes and limits of the use of participatory methodology of evaluation with municipal health managers and administrators. METHODS Qualitative research with health policymakers and managers of the Comissão Intergestores Regional (CIR – Regional Interagency Commission) of a health region of the state of Sao Paulo in Brazil. Representatives from seven member cities participated in seven workshops facilitated by the researchers, with the aim of assessing a specific problem of the care line, which would be used as a tracer of the system integrality. The analysis of the collected empirical material was based on the hermeneutic-dialectic methodology and aimed at the evaluation of the applied participatory methodology, according to its capacity of promoting a process of assessment capable to be used as a support for municipal management. RESULTS With the participatory approach of evaluation, we were able to promote in-depth discussions with the group, especially related to the construction of integral care and to the inclusion of the user’s perspective in decision-making, linked to the search for solution to concrete problems of managers. By joint exploration, the possibility of using data from electronic information systems was opened, as well as information coming directly from the users of the services, to enhance discussions and negotiations between partners. The participants were disbelievers of the replication potential of this type of evaluation without the direct monitoring of the academy, given the difficulty of organizing the process in everyday life, already taken by emergency and political issues. CONCLUSIONS Evaluations of programs and services carried out within the Regional Interagency Commission, starting from the local interest and facilitating the involvement of its members by the use of participatory methodologies, can contribute to the construction of integral care. To the extent that the act of evaluating stay invested with greater significance to the local actors, its involvement with the evaluations at the federal level can also be stimulated.
Contribution of education, occupation and cognitively stimulating activities to the formation of cognitive reserve
Authors: Baldivia Beatriz , Andrade Vivian Maria , Bueno Orlando Francisco Amodeo
Published: August 2016

Abstract The cognitive reserve (CR) concept posits that there is individual variability in processing task demands and coping with neurodegenerative diseases. This variability can be attributed to the protective effects derived from continuous cognitive stimulation throughout life, including formal education, engagement in cognitively stimulating activities and occupation. These can result in protection against age-related cognitive decline and reduce the risk of developing Alzheimer's disease. The aim of this review is to summarize the main features of CR formation and to discuss the challenges in carrying out CR research in developing countries.
Effects of functional physical activity on the maintenance of motor function in Alzheimer's disease
Authors: Fajersztajn Laís , Cordeiro Renata Cereda , Andreoni Solange , Garcia Jacqueline Takayanagi
Published: August 2016

Abstract It is widely known that older adults, even frail individuals, can improve their physical function using appropriately targeted exercise. Nevertheless, older adults with Alzheimer's disease (AD) have been excluded from the majority of studies on exercise. The functional-task physical activity program is based on activities of daily living, and may be suited for elderly people with AD because it focuses on the maintenance and stimulation of preserved abilities. In addition, session costs are substantially reduced by adopting a group approach. Furthermore, the group approach may improve the social interaction of the demented patient. Objectives: To determine whether a functional-task physical activity program in groups can maintain motor function in elderly with AD. Methods: 10 elderly diagnosed with mild or moderate AD were assigned into one of two groups: subjects with and without intervention. The intervention consisted of a 12-week function-task physical activity program in groups. Measurements: activities of daily living (Katz and Lawton & Brody questionnaires), mobility (Timed Up and Go Test, Timed Up and Go manual Test and Timed Up and Go Cognitive Test), cognition (Mini-Mental State Examination), behavioral disturbances (Neuropsychiatric Inventory I-brief) and functional balance (Berg Balance Scale). Results: A statistically significant difference between the two groups was found regarding the functional balance mean change measured by Berg scale score (p=0.046). A significant improvement of 1.60 points (95%CI[0.22;2.98]) was observed in the intervention group on this scale, while the non-intervention group showed -0.40 points (95%CI[-1.78;0.98], no change). Conclusions: It is possible to treat mild and moderate Alzheimer's patients using a group approach. The functional task physical activity program was efficient in functional balance improvement and also appeared to prevent mobility decline.
Diagnostic disclosure in Alzheimer's disease: A review
Authors: Raicher Irina , Caramelli Paulo
Published: August 2016

Abstract Although growing, the literature on research into attitudes of general and specialized physicians towards disclosing the diagnosis of dementia and Alzheimer's disease (AD), or the current practice on AD disclosure, remains limited. Moreover, information is also scarce on what caregivers, or indeed patients themselves, wish to know with regard to their diagnosis. The goal of the present article was to present a review of the current available literature on the topic of truth telling in dementia, especially in AD. The studies discussed in this review were mainly conducted in Europe, particularly in the United Kingdom, as well as the United States. Disclosure of AD diagnosis is not a common practice among physicians. In the clinical context, the discussion on diagnosis disclosure can be valuable for improving the care of AD patients and their families.
Clinical conditions and memory complaints in outpatient elderly
Authors: Magaldi Regina Miksian , Busse Alexandre Leopold , Coelho Venceslau Antonio , Apolinário Daniel , Lopes Leonardo da Costa , Satomi Erika , Kasai Juliana Yumi Tison , Jacob Filho Wilson
Published: August 2016

Abstract Memory complaints are common in elderly, and may be associated with many clinical problems. Objective: To identify clinical conditions and possible factors related to memory complaints in elderly outpatients presenting at a tertiary unit. Methods: Patients with memory complaints and normal cognitive screening tests were submitted to clinical and laboratorial testing. Radiological evaluation was performed as needed for diagnosis. Results: One hundred and seventy-seven subjects were initially evaluated, 12 were excluded because of poor and inconsistent memory complaints. Of the remainder, seventeen had criteria for dementia diagnosis. Ninety-two (55.4%) had one or more comorbid conditions possibly related to their complaints. Major depression was present in 26.0%. Sixteen patients (9.6%) had vitamin B12 deficiency, 8 were in use of inappropriate medications, and 7 (4.2%) had hypothyroidism. Other conditions diagnosed were: generalized anxiety disorder, obstructive sleep apnea syndrome, hyperparathyroidism, normal pressure hydrocephalus. Three patients had severe hearing loss (in 22 with hearing complaints); one had severe visual impairment (in 22 with visual complaints). Conclusions: Comprehensive evaluation was able to identify treatable conditions possibly related to memory complaints.
Isolation and preliminary evaluation of Mulva Neglecta mucilage: a novel tablet binder
Authors: Rahim Haroon , Sadiq Abdul , Khan Shahzeb , Chishti Kamran Ahmad , Amin Fazli , Khan Mir Azam , Abbas Sudhair
Published: August 2016

ABSTRACT The aim of this study was to evaluate binding potential of Mulva neglecta mucilage (MNM) with subsequent comparison to PVP K30. Eight batches of Diclofenac sodium tablets were prepared by wet granulation technique keeping different concentrations (4, 6, 8 & 10% w/w) of Mulva neglecta mucilage (extracted from leaves of Mulva neglecta) and PVP K30 as standard binder. The granules of formulated batches showed bulk density (g/mL) 0.49 ± 0.00 to 0.57 ± 0.00, tapped density (g/mL) 0.59 ± 0.01 to 0.70 ± 0.01, Carr's index 09.27 ± 0.95 to 19.65 ± 0.59, Hausner's ratio 1.12 ± 0.00 to 1.24 ± 0.01 and angle of repose 30.37 ± 2.90 °C to 36.86 ± 0.94 °C. Tablets were compressed to hardness 7.50 to 7.95 kg/cm2. The tablets showed 0.39 ± 0.02 to 0.39 ± 0.01% friability and 7:20 to 14:00 min disintegration time. Granules and post-compression evaluation revealed that parameters assessed were all found to be within the pharmacopoeial limits. The results (hardness, disintegration and dissolution) proved that Mulva neglecta mucilage has better binding capacity for preparation of uncoated tablet dosage form as compared to PVP K30. Among all the formulations, MN-1 to MN-4 showed slow release as compared to PV-1 to PV-4 and thereby Mulva neglecta mucilage exhibited satisfactory drug release phenomenon tablets of diclofenac sodium.
A ATUAÇÃO DO SUPREMO TRIBUNAL FEDERAL NA CRISE DA POLÍTICA DOS ESTADOS NA PRIMEIRA REPÚBLICA (1908-1911): UMA ANÁLISE A PARTIR DO PERIÓDICO JURÍDICO O DIREITO
Authors: Sato Leonardo Seiichi Sasada , Gonçalves Priscila Petereit de Paola
Published: August 2016

Resumo O objetivo do artigo é verificar a atuação do STF, entre os anos de 1908 e 1911, frente a dois dos principais temas políticos debatidos à época: dualidades eleitorais e pedidos de intervenções federais. Utilizou-se como fonte o periódico jurídico O Direito, que representou um dos principais meios de divulgação das atividades e da jurisprudência do Poder Judiciário na Primeira República. A partir de três episódios políticos documentados no periódico (Bahia em 1908, Manaus em 1910, e Rio de Janeiro em 1911), buscou-se compreender os limites da atuação do STF frente à crise da política dos estados na Primeira República.
O CÓDIGO ADMINISTRATIVO DO ESTADO NOVO: A DISTRIBUIÇÃO JURÍDICA DO PODER POLÍTICO NA DITADURA
Authors: Guandalini Jr. Walter , Codato Adriano
Published: August 2016

Resumo O artigo discute as duas versões do Decreto-Lei 1.202/39 e suas alterações durante o Estado Novo (através do Decreto-Lei 5.511/43 e do Decreto-Lei 7.518/45). Analisamos os diferentes formatos da disposição jurídica que definiu tanto os poderes formais das oligarquias estaduais depois da Revolução de 1930, quanto a agenda político-burocrática dos Departamentos Administrativos dos estados. Trata-se de avaliar a capacidade legal desses aparelhos para formular políticas e tomar decisões, precondição para entender seu poder de agenda. A análise dessa legislação permite compreender como a divisão do trabalho político e burocrático operava no Estado ditatorial, as conexões entre os seus centros de poder e a distribuição do poder pelas oligarquias.