bluuebunny/crossref_metadata_2025 huggingface dataset:
The 2017 ILAE classification of seizure types and the epilepsies: what do people with epilepsy and their caregivers need to know?
Authors: Brodie Martin J. , Zuberi Sameer M. , Scheffer Ingrid E. , Fisher Robert S.
Published: August 2019

The International League against Epilepsy (ILAE) published in the April 2017 edition of Epilepsia three companion articles on the classification of seizures and the epilepsies. These represent a long‐awaited update on the original 1981 and 1989 publications and provide a modern descriptive template. The new classification presents three levels of terminology, involving seizure types, epilepsy types, and syndromes. In this fourth paper, we present an interpretation of these new concepts for people with epilepsy and those who care for them, as well as for young medical doctors not specialized in epilepsy and nurses. Our goal in writing this paper is to ensure that everyone is speaking and understanding the same language, which is fundamental to the optimal management of people with epilepsy.
De novolate‐onset absence status epilepticus or late‐onset idiopathic generalized epilepsy? A case report and systematic review of the literature
Authors: Brigo Francesco , Tavernelli Veronica , Nardone Raffaele , Trinka Eugen
Published: August 2019

Aim. Idiopathic (genetic) generalized epilepsies (IGEs) are age‐related epileptic syndromes with typical age onset in childhood or adolescence. We report a patient withde novolate‐onset absence status epilepticus (ASE) occurring at the age of 64 years, with clinical and EEG features suggestive of late‐onset IGE. We also discuss the relationship betweende novolate‐onset ASE and late‐onset IGE, and provide a comprehensive and critical review of the available literature on late‐onset (i.e. onset ≥60 years) IGE.

Methods. MEDLINE (1966–2016 [23thApril]) was systematically searched in order to identify reports of patients with late‐onset IGE. Grey literature was also comprehensively searched.

Results. We identified nine patients with electroclinical features suggestive of late‐onset IGE. Median age at seizure onset was 71 years (range: 60–80), with a female prevalence (67%). A family history of epilepsy was reported in 67% of cases. All patients had generalized tonic‐clonic seizures, and 44% also had myoclonic seizures. Treatment and outcome were reported for six patients; all of whom reached seizure freedom under monotherapy with valproic acid (83%) or lamotrigine (17%) (range of follow‐up: 3 to 24 months).

Conclusion. Late‐onset IGE are entities with unknown prevalence and incidence, and should be differentiated on the basis of late‐onset reactivation of previous IGE. Late‐onset IGEs are probably unrecognized or misdiagnosed, based on a common misconception that all elderly individuals with first‐ever seizures have focal symptomatic epilepsy. Late‐onset IGE should be actively investigated by accurate history taking aimed at identifying seizures, which may have been unnoticed, and familial antecedents of epilepsy. In elderly patients presenting withde novolate‐onset ASE, a diagnosis of late‐onset IGE should be considered in the differential diagnosis, particularly in atypical cases (e.g. absence of triggering factors, coexistence of generalized tonic‐clonic or myoclonic seizures, and interictal generalized epileptiform discharges).
Chromosome 14q11.2‐q21.1 duplication: a rare cause of West syndrome
Authors: Çetin Özdem Ertürk , Yalçınkaya Cengiz , Karaman Birsen , Demirbilek Veysi , Tüysüz Beyhan
Published: August 2019

Proximal duplication of chromosome 14q, including the FOXG1 gene located on 14q12, is a rare condition characterised by developmental delay, dysmorphic craniofacial features, epilepsy, and severe speech delay. Here, we report a patient with West syndrome whose chromosome analysis revealed 14q11.2‐21.1 duplication. The patient was admitted due to infantile epileptic spasms at eight months of age, motor developmental delay, and dysmorphic features. Chromosome and array‐CGH analysis revealed de novo 14q11.2‐21.1 duplication, spanning ∼20 Mb (minimal interval chr14:20203610_40396835). The patient was followed up to 13 years of age, and at the last examination was shown to have severe speech delay, seizures, and continuous spike‐and‐wave activity on EEG. The possibility of this chromosomal abnormality should be kept in mind in patients with developmental delay, epilepsy, and hypsarrtyhmia, in the absence of any structural brain lesion or metabolic aetiology.
A case of perioral myoclonia with absences and its evolution in adulthood?
Authors: Surmelı Reyhan , Kurucu Hatice , Yalcın Ayse Destina , Yenı Seher Naz
Published: August 2019

The rare syndrome of perioral myoclonia with absences (POMA) is described as a specific type of idiopathic generalized epilepsy in which absence seizures are accompanied by prominent perioral myoclonus as a consistent symptom. We present a 52‐year‐old man who was referred to our department due to treatment‐resistant epilepsy. Typical seizures were described as rhythmic twitching of the lips which started at six years old, and his first convulsive seizure occurred at around 20 years old. Based on video‐EEG recordings, we present two distinct EEG patterns accompanied by slight differences in clinical manifestations, which appear to be atypical of POMA. Firstly, consciousness was preserved during seizures, with no manifestation of absences. Secondly, regarding the EEG features, in some of the seizures, the perioral motor symptoms were tonic rather than myoclonic. The defining features of POMA are discussed in relation to this case.
Epileptic ictal strabismus: a case report and review of the literature
Authors: Brigo Francesco , Alessandrini Franco , Ragnedda Giammario , Canu Piera , Tavernelli Veronica , Bratti Arianna , Nardone Raffaele
Published: August 2019

Ictal strabismus, sometimes associated with epileptic nystagmus, is an extremely rare epileptic phenomenon, suggestive of cortical involvement in monocular eye movement control. We describe a patient with ictal disconjugate contraversive horizontal eye deviation of cortical origin as the main clinical feature of a focal seizure. A 17‐year‐old, previously healthy woman had a seizure characterized by initial rightward conjugate eye deviation, followed by convergent strabismus due to adduction of the right eye towards the nose without conjugate left eye abduction (esotropia), forced leftward head deviation with impaired awareness, and subsequent evolution into a bilateral tonic‐clonic seizure. Postictal and interictal neurological status were unremarkable; more specifically, neuro‐ophthalmological examination revealed no nystagmus or altered eye motility. Ictal EEG showed a rhythmic theta activity over the right posterior temporal region, involving fronto‐central regions when strabismus appeared. MRI showed cortical dysplasia in the right temporal lobe. Due to the low spatial resolution of scalp EEG, we could not identify with precision the symptomatogenic zone underlying ictal strabismus. However, the concomitant appearance of rhythmic theta activity over the right fronto‐central region and the leftward head version with MRI perfusion sequences, showing cerebral blood flow increase in the right frontal eye field area, suggest involvement of the right frontal lobe. [Published with video sequence onwww.epilepticdisorders.com].
Biallelic loss‐of‐function UBA5 mutations in a patient with intractable West syndrome and profound failure to thrive
Authors: Daida Atsuro , Hamano Shin‐ichiro , Ikemoto Satoru , Matsuura Ryuki , Nakashima Mitsuko , Matsumoto Naomichi , Kato Mitsuhiro
Published: August 2019

Mutation of the gene encoding ubiquitin‐like modifier‐activating enzyme 5 (UBA5) causes autosomal recessive early‐onset epileptic encephalopathy. UBA5 acts as an E1‐activating enzyme in the ubiquitin‐fold modifier 1 pathway, which is important for unfolded protein elimination and regulation of apoptosis, and has been linked to human diseases. We identified biallelic mutations in UBA5 in a Japanese boy with intractable West syndrome, profound failure to thrive, and severe cerebral and cerebellar atrophy. The boy presented with epileptic spasms and hypsarrhythmia at the age of three months. He was diagnosed with West syndrome, however, treatments with adrenocorticotropic hormone and several antiepileptic drugs were ineffective. MRI findings were initially normal, but subsequently showed a progression of cerebellar and cerebral atrophy. By the age of seven years, he had not achieved any developmental milestones; he had daily epileptic spasms and tonic seizures and profound failure to thrive. Gene analysis revealed novel compound heterozygous mutations in UBA5; a microdeletion encompassing the entire UBA5 gene and a putative disease‐causing missense mutation in the catalytic domain. These biallelic variants may have caused loss of function, accounting for the observed clinical symptoms. Intractable infantile epileptic spasms, failure to thrive, and severe neurological impairment may be characteristic of patients with UBA5 mutations.
Lacosamide for SCN2A‐related intractable neonatal and infantile seizures
Authors: Hadar Flor‐Hirsch , Eli Heyman , Ayelet Livneh , Orit Reish , Nathan Watemberg , Ita Litmanovits , Anat Ben Sason Lilli , Dorit Lev , Tally Lerman Sagie , Haim Bassan
Published: August 2019

Voltage‐gated sodium channel alpha subunit 2 (SCN2A) gene mutations are associated with neonatal seizures and a wide range of epilepsy syndromes. Previous reports suggest that traditional sodium channel blockers (SCBs) such as phenytoin, carbamazepine, and lamotrigine have a beneficial effect on SCN2A‐related neonatal seizures, as they counteract the gain‐of‐function effect of mutated Nav1.2 channels. Additionally, SCBs are beneficial against other sodium and potassium channel‐related neonatal seizures. There are, however, few reports describing the effect of the new SCB lacosamide against neonatal and infantile epileptic seizures. We report herein two neonates with intractable neonatal seizures with SCN2A pathogenic missense variants. Both infants showed temporary seizure relief following IV administrations of phenytoin, but were resistant to a combination of antiepileptic drugs, while complete seizure control was achieved following lacosamide administration. We suggest that SCBs, e.g. phenytoin, should be introduced early for refractory neonatal seizures of non‐lesional and presumably genetic origin. If any beneficial response to a SCB is noted, this should prompt an initiation of additional SCBs. New clinical trials will provide data on the efficacy and safety of the new SCB lacosamide for genetic neonatal seizures and perhaps neonatal seizures in general.
Why the TimeToStop trial failed to recruit: a survey on antiepileptic drug withdrawal after paediatric epilepsy surgery
Authors: Lamberink Herm J. , Geleijns Karin , Otte Willem M. , Arzimanoglou Alexis , Helen Cross J. , Korff Christian M. , Ramantani Georgia , Braun Kees P.J. ,   on behalf of the TimeToStop trial group
Published: August 2019

Aims. Following the results of the multicentre European retrospective “TimeToStop” cohort study, we initiated a randomised trial to determine cognitive benefits of early postoperative antiepileptic drug withdrawal. Unfortunately, the trial failed to recruit and was terminated, as almost all parents preferred early drug withdrawal. The objectives of the current survey were to obtain insight into current practices regarding drug withdrawal after paediatric epilepsy surgery among epileptologists, and better understand the reasons for difficulties in recruitment.

Methods. A survey was sent to three international epilepsy surgery networks, questioning drug withdrawal policies. Forty‐seven (19%) surveys were returned.

Results. For polytherapy, withdrawal was started at a median of three and six months by the TimeToStop collaborators and other paediatric epileptologists, respectively. Withdrawal was completed at a median of 12 and 20 months, respectively. For monotherapy, tapering was initiated at five and 11 months in these two groups, and ended at a median of seven and 12 months, respectively. Most TimeToStop collaborators believed that it was not justified to wait 12 months after surgery before reducing AEDs, regardless of the number of AEDs taken.

Conclusion. Current AED policies in Europe have changed as a consequence of the retrospective TimeToStop results, and this accounts for why recruitment in a randomised trial was not feasible.
West syndrome, developmental and epileptic encephalopathy, and severe CNS disorder associated with WWOX mutations
Authors: Shaukat Qudsia , Hertecant Jozef , El‐Hattab Ayman W. , Ali Bassam R. , Suleiman Jehan
Published: August 2019

Aims. Mutations in the WWOX gene have been reported in a number of patients with various neurological disorders including spino‐cerebellar ataxia, intellectual disability, epilepsy, and epileptic encephalopathy. We aimed to study the clinical, electrographic, and imaging features of two new cases with WWOX mutations and compare them to previously reported cases with WWOX mutations.

Methods. We assessed two unrelated children from two consanguineous families who had severe neurological disorder including early‐onset spastic quadriplegia, profound developmental delay, epilepsy, and West syndrome.

Results. Based on whole‐exome sequencing, we identified homozygous null mutations in WWOX in both children, and further addressed the genotype‐phenotype correlation. In addition, we provide a detailed review of the previously reported cases of WWOX‐related neurological disorders and compare them to the children in this report.

Conclusions. The findings in this report expand the clinical phenotype associated with WWOX mutations and confirm a well characterised severe central nervous system disorder in association with biallelic null mutations in WWOX. This syndrome consists of profound psychomotor delay, early‐onset spastic quadriplegia, and refractory epilepsy including epileptic encephalopathy, acquired microcephaly, and growth restriction. This can be associated with progressive brain atrophy, suggestive of neurodegeneration. Identification of this phenotype by clinicians may help with early diagnosis and appropriate genetic counselling.
Cortical surface intracranial electrodes identify clinically relevant seizures missed on scalp EEG after traumatic intracranial hemorrhage
Authors: Marcellino Chris R. , Lapalme‐Remis Samuel , Rabinstein Alejandro A. , Van Gompel Jamie J. , Worrell Gregory A. , Payne Eric T. , Hocker Sara
Published: August 2019

Seizures and other electrophysiological disturbances are an under‐recognized cause of coma, focal deficits, and prolonged encephalopathy following subdural hematoma evacuation. In these patients, it is possible that seizures remain unrecognized on scalp EEG. It has been shown that a high burden of seizures and other electrophysiological disturbances exist following surgical evacuation and underlie the encephalopathy commonly seen in this patient population, predisposing them to medical complications and confounding estimates of prognosis. As part of a research protocol, we are performing intraoperative placement of cortical surface (non‐parenchyma penetrating) intracranial EEG on patients who present after trauma and require emergent decompressive hemicraniectomy.

In this case report of a patient with high‐velocity traumatic epidural, subdural, and subarachnoid hemorrhages, we identified frequent non‐convulsive seizures or seizure‐like SIRPIDs with intracranial cortical surface monitoring that were not identified on simultaneous scalp EEG. Stimulation consistently triggered these electrographic seizures in addition to rhythmic lateralized periodic discharges. His mental status improved rapidly after resolution of these electrographic seizures shortly after increasing antiseizure medications, suggesting that they may have been contributing to his encephalopathy. More research is needed to determine the frequency of this phenomenon and determine whether treatment of such seizures improves patient outcomes.
Yerleşim Yerlerine Göre Anne Baba Tutumlarının Okul Öncesi Çocukların Sosyal Becerilerine Etkisi
Authors: TEMEL Dudugül , TÜRKOĞLU Bengü
Published: August 2019

Bu araştırma, köy ve kentte yaşayan, anasınıfına devam eden
çocukların anne baba tutumlarının ve bazı değişkenlerin sosyal becerilerinde
farklılık yaratıp yaratmadığının belirlenmesi amacıyla yapılmıştır. Araştırma
Konya ili Kadınhanı ilçesine bağlı köylerde, anasınıfına devam eden 140 köy
çocuğu ile Konya ili Karatay ilçesinde anasınıfına devam eden 180 çocuk olmak
üzere toplam 320 çocuk üzerinde yürütülmüştür. Araştırmada çocukların sosyal
becerilerini belirlemek amacıyla “Sosyal Becerileri Değerlendirme Ölçeği”,
çocuklar ve aileleri ile ilgili bazı bilgileri elde etmek amacıyla araştırmacı
tarafından hazırlanan “Kişisel Bilgi Formu” ve anne baba tutumunu belirlemek
amacıyla “Anne- Babalık Stilleri ve Boyutları Ölçeği” kullanılmıştır. Araştırma
sonucunda; anne baba tutumlarından demokratik anne tutumunun, çocukların
cinsiyetinin, anne eğitim düzeyinin ve kardeş sayısının kent merkezindeki
çocukların sosyal becerileri üzerinde anlamlı bir farklılığa yol açtığı tespit
edilmiştir. Anne baba tutumlarından demokratik baba tutumunun, otoriter anne
-baba tutumunun, izin verici anne- baba tutumunun, çocukların yaşının,
anne–baba yaşının, anne-baba mesleğinin, baba eğitim düzeyinin çocukların
sosyal becerileri üzerinde anlamlı bir farklılığa yol açmadığı saptanmıştır.
Anne baba tutumlarından demokratik anne-baba tutumunun, otoriter anne–baba
tutumunun, izin verici baba tutumunun köy merkezinde bulunan çocukların sosyal
becerilerinde anlamlı bir farklılığa neden olduğu tespit edilmiştir. İzin
verici anne tutumunun, çocukların yaşının, cinsiyetinin, anne-baba yaşının,
anne–baba eğitim durumunun, anne–baba mesleğinin ve kardeş sayısının çocukların
sosyal becerileri üzerinde anlamlı bir farklılığa neden olmadığı görülmüştür.
Çocukların Medya Okuryazarlık Düzeylerinin ve Kullanım Alışkanlıklarının Demografik Değişkenler Açısından İncelenmesi
Authors: ASLAN Alper , TURGUT Yiğit Emrah , GOKSU İdris , AKTI ASLAN Seda
Published: August 2019

Bu araştırmada ortaokul düzeyindeki çocukların medya kullanım alışkanlıklarının ve çeşitli değişkenlere göre medya okuryazarlık düzeylerinin ortaya çıkarılması amaçlanmaktadır. Nedensel-karşılaştırma yöntemi ile gerçekleştirilen bu çalışmanın örneklemini Türkiye’nin 7 coğrafi bölgesinden seçilen 1500 çocuk oluşturmaktadır. Araştırma verileri 2017 yılında toplanmıştır. Araştırmada her üç çocuktan ikisinin mobil internet kullandığı, günlük 1-2 saat televizyon izlediği ve internet kullandığı belirlenmiştir. Çocuklar arasında televizyon izlemek en popüler etkinlik iken bunu her iki çocuktan birisinin gerçekleştirdiği müzik dinleme, sosyal ağları, cep telefonlarını ve interneti kullanma etkinliklerinin takip ettiği tespit edilmiştir. Çocukların demografik özelliklerine göre, cinsiyet açısından erkekler çocukların kadınlara; coğrafi bölgeler açısından Güneydoğu bölgesinde yaşayanlar çocukların diğer bölgedekilere kıyasla medya okuryazarlık düzeylerinin anlamlı olarak düşük olduğu tespit edilmiştir. Ayrıca çocukların sınıf düzeyleri arttıkça medya okuryazarlık düzeylerinin de genel olarak arttığı belirlenmiştir. Çocukların medya kullanım alışkanlıklarına göre, mobil internet kullanmayan çocukların mobil internet kullananlara, günde 1-2 saat televizyon izleyen çocuklarında 7-8 saat televizyon izleyenlere kıyasla medya okuryazarlık düzeylerinin anlamlı olarak yüksek olduğu ortaya çıkmıştır.
Demultiplexing Nanopore reads with LAST v4
Authors: A Eccles David
Published: August 2019

This protocol is for a semi-manual method for read demultiplexing, as used after my presentation Sequencing DNA with Linux Cores and Nanopores to work out the number of reads captured by different barcodes. Input: reads as a FASTQ file, barcode sequences as a FASTA file Output: reads split into single FASTQ files per target [barcode] Note: barcode / adapter sequences are not trimmed by this protocol
DEMoNS protocol for measurement and analysis of eye movements v1
Authors: Nij Bijvank Jenny
Published: August 2019

For questions, send an email to info.demonsprotocol@gmail.com The complete protocol and instructions on measurement and analysis of eye movements with the DEMoNS protocol. Quantitative saccadic testing is a non-invasive method of evaluating the neural networks involved in the control of eye movements.The DeMONS protocol isa standardized and reproducible protocol for infrared oculography measurements of eye movements and analysis, which can be applied for various diseases in a multicenter setting. In the accompanying manuscript in PLoS ONE, descriptive and reproducibility values are listed of all parameters. Download the file Demons_all_files forthe whole protocol including the matlabfiles, or download files seperately in the 'Steps' tab
RUSSIAN FEDERATION IN THE CONDITIONS OF MULTIPOLAR TRANSIT
Authors: Kondratenko O. Yu
Published: August 2019

The state of formation of a new system of world order and international relations is outlined. It was found out that there is a transition from post-bipolar to multi-polar world order. At the moment, the world is in a state of transit or transitive order, since the old world-system, which took shape after the end of the Cold War, went back to the past, while the new paradigm of the world order is the subject of uncertainty. The new world order, whose outline is more and more clearly distinguished by a distortion, is to be understood rather as a global mess that is a hallmark of the present stage of globalization. Under these circumstances, large, medium and small states are trying to find their place in the future of a multipolar world, which, according to the forecasts of most experts, will be multipolar. The United States is gradually moving away from its role as a world leader trying to focus ondomestic issues. Among the new centers of power are traditionally China, which is increasingly expanding its influence by expanding its economic presence in different regions through investments in industrial and infrastructure projects. The Russian Federation is compelled to seek a compromise from the West in the sense of recognizing its Russian sphere of strategic interests at the regional and partly global level in order to affirm the status of one of the centers of influence comparable in its power with the USA and China. A major geostrategic task for Russia is the return of the world to the realities of the twentieth century, or during the rhetoric of classical realism, which prevailed such categories as "zones of influence", "buffer zones", "balance of power", "balance of interests". It has been found that the resources available in Russia do not serve as a full-fledged geopolitical basis for designing global influence. That is why the Russian Federation has resorted to aggression and destabilization of the transitive world order in order to support controlled chaos in different directions.
Las voces gallegas incorporadas al DRAE: de 1992 a 2001
Authors: Campos Souto Mar , Pérez Pascual José Ignacio
Published: August 2019

Las voces gallegas incorporadas al DRAE: de 1992 a 2001.
Efficiency of midsize enterprises in the free-trade-zone in Barranquilla – Colombia
Authors: Fontalvo Hererra Tomás José , Morelos Gómez José , Olivos Aarón Saúl
Published: August 2019

In this investigation, the efficiency of midsize companies in the free-trade-zones of Barranquilla was analyzed. For this, a model supported by Data Envelopment Analysis structure (DEA) was proposed which required a rational analysis to define input and output variables in order to measure and test the efficiency of 63 companies under study in 2016 and 2017. The Chamber of Commerce of Barranquilla with which an empirical analysis was performed to measure the efficiency of the sector provided primary information. The research showed that from 2016-2017 the percentage of efficient enterprises improved from 11.11% to 17.46% while 6.34% of companies maintain their efficiency, 42.85% showed improvements and 50. 79% of companies decreased their efficiency.
ENFOQUES TERRITORIALISTA, SISTÊMICO E INTERDISCIPLINAR COMO REFERÊNCIA EM EXPERIÊNCIAS DE ASSOCIATIVISMO TERRITORIAL
Authors: Buhr Gladis Maria Bazzani , Dallabrida Valdir Roque
Published: August 2019

Na perspectiva da sustentabilidade, entende-se que uma estratégia de desenvolvimento territorial precisa atender a três critérios: conceber o território como referência, contemplar uma abordagem sistêmica e atender aos pressupostos da interdisciplinaridade. Propôs-se identificar enfoques teóricos sobre desenvolvimento que melhor contemplem esses critérios, com o fim de avaliar suas possíveis contribuições para o avanço da prática de experiências de associativismo territorial. Optou-se pelos enfoques sobre agroecologia, sistemas agroflorestais e agroalimentares, ecofeminismo, ecomarxismo e economia circular, como mais adequados para orientar tais experiências. Utilizou-se a pesquisa bibliográfica e informações documentais in loco, tomando o caso da Associação Nova Concórdia (ANC) no Oeste Catarinense como campo de observação e análise. No caso da ANC, verificou-se que a iniciativa já abarca algumas características de parte desses enfoques, no entanto, precisa avançar.
Environmental Standardization in the System of Technical Regulation
Authors: Danilov-Danilyan V.I. , Rosenthal O.M.
Published: August 2019

The main sources of environmental hazards at various stages of the product life cycle are described, and ways are offered to remedy the current situation by: creating uniform rules for ensuring the environmental safety of products, taking into account its specific characteristics; the development of standards, the technical requirements of which would protect the environment from the harmful effects of products at all stages of its life cycle; the formation of a new category of standardization – regional standards that ensure the environmental safety of technical regulation, taking into account the particularities of the regions.
Working Together in Learning Analytics Towards the Co-Creation of Value
Authors: Dollinger Mollie , Liu Danny , Arthars Natasha , Lodge Jason
Published: August 2019

The value of technology lies not only with the service or functionality of the tool, but also with its subsequent value to the people who use it. New learning analytics (LA) software and platforms for capturing data and improving student learning are frequently introduced; however, they suffer from issues of adoption and continued usage by stakeholders. Scholars have previously suggested that it is not enough to introduce stakeholders (e.g., teachers and students) to LA technologies; they must also be a part of the LA creation and design process. In this paper, we will continue the ongoing work to clarify and compare different approaches of human-centred design through an overview of participatory frameworks in LA (co-design, co-creation). We will also present a case study using an LA tool used and developed within several Australian universities that was utilized over six years as an example of how LA designers can co-create dynamic platforms with teachers. Implications of participatory design frameworks in LA will also be presented through a discussion of the costs, challenges, and benefits of adopting human-centred design.
Getting Prepared to Be Prepared: How Interpersonal Skills Aid Fieldwork in Challenging Contexts
Authors: Alberti Carla , Jenne Nicole
Published: August 2019

This article deals with fieldwork in challenging research contexts that make preparation for field research particularly difficult. Challenging contexts include generally insecure places, politicized contexts, and unknown settings. Drawing on our experience in the field, we discuss four challenges that are common across these contexts: access, positionality, researcher well-being, and research design and data collection. Bringing together insights from fieldwork with urban elites and in the countryside, this paper describes problems that occurred in both settings and identifies a set of interpersonal skills that helped the authors to tackle the challenges of the field and seize the opportunities it offered. This article posits that recognizing the importance of certain interpersonal skills, namely: openness, empathy, humility, and flexibility, precedes the identification of practical tools. Interpersonal skills, instead, focus on a general attitude that underlies researchers’ capacity to make informed choices about specific courses of actions, preparing fieldworkers to be prepared to confront problems once they arise.
REMOVAL OF DIVALENT CADMIUM IONS FROM AQUEOUS SOLUTION USING LANTANA CAMARA LEAVES BIOCARBON
Authors: Starlin Shyla S. , Mohan Kumar R. , Singanan M.
Published: August 2019

The objective of this study is to investigate the removal of divalent cadmium ions from an aqueous solution using Lantana camara leaves biocarbon (LCBC). Batch experiments are conducted to test the effects of various parameters such as pH, initial metal ion concentration, amount of biocarbon, and contact time on the cadmium removal process at room temperature, which allows establishing as the optimum conditions a pH value of 4.0 and 2.5g/100 mL of biocarbon dose at the equilibrium time of 180 min. The maximum percentage removal of cadmium is 93.30%. Langmuir and Freundlich adsorption isotherms are used to verify the adsorption parameters, and the experimental data is well fitted to the Langmuir model. Analysis of the biosorption kinetics shows that the pseudo-second-order model is well fitted for Cd (II) ions removal. The correlation coefficient (r2) for the second-order model is 0.9848. The results reveal LCBC as an efficient, low cost, and harmless to environment adsorbent for the removal of Cd (II) ions in the biosorption process.
Incidence of Yahoo-Plus activities among in-school adolescents in Delta State, Nigeria
Authors: Adebayo David Obafemi , Julius Elizabeth , Fasasi Lukman
Published: August 2019

Engaging in inhuman ritual activities for wealth creation, popularly known as Yahoo-Plus, is at unimaginable levels in Nigerian societies, particularly in Delta state now. There are widespread incidences of missing female university undergraduates and other girls of school age. It is quite disheartening that the younger generations are caught in the evil and mindless acts of killing for money rituals. This study examined the incidence of Yahoo-Plus activities among in-school adolescents in Delta State, Nigeria. The study was a quantitative type and descriptive survey design was adopted. A total of 800 in-school adolescents at both secondary and tertiary institutional levels were purposively selected as samples for the study. An inventory entitled â€˜Incidence of Yahoo-Plus Activities Inventoryâ€™ was designed to collect data. The results revealed that students at both secondary and tertiary institutions attested that Yahoo-Plus activities were prevalent due to youngstersâ€™ desire to get rich quickly, rather than waiting or toiling. Keywords: Incidence, Yahoo-Plus, in-school, adolescents, Delta state, Nigeria
Influence of motivations for social media use on cyberbullying behaviours among undergraduates in Malaysian public universities
Authors: Adebayo David Obafemi , Ninggal Mohd Tajudin , Bolu-Steve Foluke Nike
Published: August 2019

In modern times, social media platforms have become veritable tools of communication and interaction amongst young adults in the university environment as well as the larger society. However, the platform has continued to cause serious psychological and emotional trauma to users through cyberbullying activities. This study examined the influence of motivations for social media use on cyberbullying behaviours (CBB) among undergraduates in Malaysian public universities. It was a quantitative type and it adopted survey design. A total sample of 400 undergraduates were purposively selected from Universiti Teknologi Malaysia. Self-designed questionnaire entitled Motivation for social media use and CBB was used for data collection. Data were analysed using Structural Equation Modelling Partial Least Squares 3. The findings revealed that undergraduates were more socially motivated for social media activities than for academic motives; thus, the reason for experiences of cyberbullying. Also, there was a significant relationship between motivations for social media use and CBB.

Keywords: Motivation, social media use, cyberbullying behaviours, public universities.
Caminhar e desvelar paisagens
Authors: Cabral Arthur Simões Caetano , Bartalini Vladimir
Published: August 2019

Muito mais do que extensão do território que se abrange com um lance de vista, a paisagem é presença que se revela pelo caminhar. E não se revela cabalmente ou por completo, não só porque a todo visível corresponde um invisível, mas também porque a completude transformaria a paisagem em mero objeto destituído de horizontes, ou seja, de possibilidades e de mistério. Assume-se aqui que a riqueza de sentidos da paisagem não se limita à sua excepcionalidade, mas é extensiva às situações banais, e que o desvelamento poético é o modo de trazer a paisagem à presença sem destruir o seu segredo. Para dar tratos ao assunto, o presente artigo toma por referências reflexões tanto de pensadores (alguns dos quais pensadores da paisagem) quanto de poetas, e apóia-se no conto O recado do morro, de Guimarães Rosa, para elaborar a relação entre a paisagem, o caminhar e a revelação poética.
O controle da paisagem urbana - “rolêzinho”
Authors: Sousa Rafael Lopes de , Gomes Álvaro Cardoso , Dias Luiz Antonio
Published: August 2019

Neste artigo analisamos paisagens em transição e momentos de rupturas, que se evidenciam nas intervenções e questionamentos que os jovens da periferia trazem à tona, a fim de encaminhar propostas e rediscutir a agenda urbana da contemporaneidade. A análise decorre da problematização do caráter simbólico ou estratégico que o “rolêzinho” e sua trilha sonora – o “funk ostentação” – desempenham como alternativa de cultura e lazer para os jovens periféricos. Considerando tal perspectiva investigamos o incômodo que o aparecimento cênico dos “rolêzinhos” despertou nos centros iluminados da cidade e o paradoxal fascínio que sua trilha sonora – o “funk ostentação” – despertou na classe média.
A construção de espaços provisórios na literatura latino-americana
Authors: Godoy José Roberto Araújo de
Published: August 2019

Este artigo procura investigar a construção de espacialidades como procedimento artístico, buscando inter-relações entre literatura e urbanismo. O objetivo principal é entender como determinados territórios passam a operar segundo regras próprias, e como suas peculiaridades espaciais, notadamente seu caráter provisório, se refletem em narrativas ficcionais. Determinadas “ilhas urbanas” nas cidades latino-americanas são nosso campo de investigação, em especial o bairro de Flores, em Buenos Aires, e o campus da UnB, durante o regime civil-militar brasileiro, no final dos anos 1960 e no começo dos anos 1970. Áreas que serão relatadas pelo escritor argentino César Aira e o romancista brasileiro Milton Hatoum.
A representação da realidade periférica em Letras de Liberdade
Authors: Brandileone Ana Paula Franco Nobile , Santos Caroline Helena dos
Published: August 2019

Apesar da diversidade que caracteriza a narrativa brasileira contemporânea, há três linhas de força dominantes: a presentificação, o retorno ao trágico e a violência. O caráter realista de grande parte dessa produção se revela como possibilidade não apenas de representação estética, mas também de intervenção ética e política no mundo real, principalmente quando se trata da realidade periférica. Nesse contexto, este artigo tem por objetivo investigar, sob a luz dos estudos de Patrocínio (2013), Schollammer (2011), Resende (2008), Foucault (1999), Michaud (1989), entre outros estudiosos, como se dá a representação da realidade marginal no conto “Lembranças ao vento”, de Márcio Marcelo do Nascimento Sena, inserido na antologia organizada por Fernando Bonassi (2000), Letras de Liberdade.
(Re)existência nas ruas
Authors: Baldini Lauro José Siqueira , Ortolano Ana Elisa Volpato
Published: August 2019

Tendo como referencial teórico-analítico a Análise do Discurso Materialista, este artigo se volta para as disputas de sentidos que envolvem a presença/permanência da população de rua na cidade de Campinas. Recortamos como corpus textos institucionais do Serviço de Saúde Dr. Cândido Ferreira, falas e músicas do programa “Destilado da Rua” e do documentário “Devolvam nosso Microfone”, um artigo do Jornal Brasileiro de Psiquiatria, um panfleto da prefeitura de Campinas e a contravenção de vadiagem do Código Penal Brasileiro. O que a singularidade do nosso objeto deu a ver é uma articulação incontornável entre dois objetos paradoxais: a loucura e a pobreza. Essas são duas discursividades com genealogias específicas que se articulam e se atravessam na produção histórica de mecanismos institucionais de controle dos corpos-sentidos na/da cidade.
Marcas da resistência nos muros da Universidade
Authors: Araujo Érica Daniela de
Published: August 2019

Neste artigo, analisamos, a partir da perspectiva teórica da Análise de Discurso, o funcionamento discursivo em duas pichações inscritas nos muros da Universidade Federal de Uberlândia, campus Santa Mônica. Buscamos compreender os possíveis efeitos de sentidos por elas produzidos, considerando sua constituição, formulação e circulação (Cf. ORLANDI, 2005b). Em nossa análise, essas pichações, escrituras da luta pelo pertencimento em uma sociedade de segregações e de exclusões, se marcam como formas de resistência ao já significado pelo discurso urbano (Cf. ORLANDI, 2004), dado que as posições-sujeito aqui analisadas questionam as evidências, jogam com o equívoco e expõem o não-dito.
Um site como ferramenta de identificação de uma agenda pública em uma pequena cidade
Authors: Prado Magaly Parreira do , Alexandri Adrian
Published: August 2019

Sem meios de comunicação locais estruturados, como uma cidade pode ser informada sobre seus principais problemas? O desafio em criar uma plataforma digital jornalística para Gonçalves (Minas Gerais), passa pela estratégia de engajar seus moradores no uso das ferramentas no intuito de discutir e apontar soluções relativas as principais questões identificadas por eles. Em uma pesquisa com dez lideranças da região – à luz de conceitos de agenda pública, engajamento e laços sociais – discutiu-se como se dá a comunicação e quais são os temas prioritários para a cidade. A partir dos resultados, de que modo a prática do jornalismo hiperlocal pode dar visibilidade a um futuro agendamento e o consequente envolvimento nos debates para melhoria daquilo que é mais urgente?
A escrita subversiva de “n. d. a.”
Authors: Gonçalves João Batista Costa , Amaral Marcos Roberto dos Santos
Published: August 2019

A escrita compreendida conforme deriva estrutural que dissemina sentidos através do deslocamento de relações entre fontes e marcas escriturais configura uma problematização de concepções logocêntricas do ato de escrever e sua legibilidade, as quais se fundamentam, sobretudo, em noções de representação, identidade, autoria e tessitura textual canônica. Nesse sentido, problematizaremos, neste artigo, como a escrita de “n. d. a.”, de Arnaldo Antunes, estrutura-se por relações de sentido que dispensam imperativos de criação que rastreiem uma fonte produtora e um sentido estável, por meio da assunção de imagens do realismo grotesco (BAKHTIN, 1987). Para tanto, fundamentamo-nos em Derrida (1972), especificamente, quando trata da questão da escritura como marca em deriva e da relação dessa questão com a da assinatura; e Bakhtin (1987), quando trata do princípio material e corporal da cultura cômica popular. Enfim, pretendemos indicar que as relações escriturais desconstrutoras características das poesias de “n. d. a.” tecem-se pelo descentramento de práticas de produção discursiva pautadas em relações de sentido reduzidas à identificação de intenção autoral a um texto e à organização de formas discursivas referenciais e objetivas.
“PL do agrotóxico”
Authors: Resende Sheilla Maria
Published: August 2019

A propósito das discussões sobre o Projeto de Lei n. 6.299/2002, o “PL do agrotóxico”, que dispõe acerca da comercialização e uso de agroquímicos nas lavouras, pretendemos lançar luz sobre a ideia de que o lastro que garante o efeito de descrição do real nos discursos do agronegócio encontra-se na rede de memórias de um passado colonial latifundiário-escravocrata recente sobre e sob a qual significamos. A língua, de acordo com a perspectiva teóricometodológica com a qual trabalhamos, a análise do discurso materialista, é opaca, e dissimula em sua materialidade sintática conflitos, tensões e heterogeneidades. Ao debruçar-nos sobre asanálises feitas de alguns recortes discursivos a respeito das discussões sobre o PL, veremos que o agronegócio fala “por si”, ao mesmo tempo em que a agricultura familiar é “falada sobre”. Perceberemos, ainda, que o pequeno agricultor, produtor de alimentos, não de commodities, resiste em silêncio. Silêncio latente nos discursos fundados sob uma pretensa “lógica” de máxima eficiência dos territórios. Discursos que circulam e são significados sob um efeito de evidência conferido graças não somente a uma memória de posse violenta dos nossos territórios, mas também à interdição de outros sentidos para a relação homem-terra.
Impact of DNA purification method and primer selection on 16S rRNA gene metabarcoding on wine
Authors: Cerutti Francesco , Cravero Diego , Costantini Antonella , Pulcini Laura , Modesto Paola , Acutis Pier Luigi , Vaudano Enrico , Peletto Simone
Published: August 2019

Aim: The high-throughput sequencing methods have revolutionized the study of the microbiota in different matrices including those of the grapevine production chain. DNA extraction is a crucial step in the sample processing. In this study, we compared different DNA purification methods and two primer sets for 16S rRNA gene metabarcoding to evaluate the best protocol to explore the wine microbiota by metabarcoding.Methods and results: We collected a wine from Barbera grapes after malolactic fermentation previously inoculated by Oenococcus oeni starter. The same sample was used to evaluate the best performing protocol to study the wine microbiota. DNA was purified using nine different methods and then amplified for the 16S rRNA gene with two primer sets (according to Illumina or Earth Microbiome Project protocols). The obtained amplicons were then sequenced in a single sequencing session on an Illumina MiSeq. We evaluated the best protocol considering DNA concentration and purity, alpha (Observed species) and beta diversity from metabarcoding analysis.The sequencing generated 36,031,756 reads in total. Although no statistically significant difference was observed between purification methods or primer sets, better results were obtained with phenol-chloroform DNA purification combined to Earth Microbiome Project primers.Metabarcoding was able to highlight the domination of the inoculum, O. oeni, representing the main species of the analyzed wine microbiota.Conclusion: Our data show that, for the tested wine, metabarcoding output is more influenced by the primer set than by the DNA purification method. Moreover, the metabarcoding detected that O. oeni represents the main species, evidencing the domination of the inoculum done with lyophilized commercial preparation of this species. Other lactic acid bacteria are present at a much lower abundance.Significance and impact of the study: This is the first report applying the 16S rRNA gene metabarcoding to study the microbiota of wine. For this reason, the evaluation of alternative methods for DNA processing is essential for future research using this innovative methodology.
PEMETAAN DAERAH RAWAN LONGSOR LAHAN DI KECAMATAN DAU, KABUPATEN MALANG DENGAN MENGGUNAKAN PENDEKATAN GEOMORFOLOG
Authors: Meviana Ika , Sari Ulfi Andrian
Published: August 2019

Bencana longsor lahan merupakan salah satu bencana alam geologi yang dapat menimbulkan korban jiwa dan kerugian material yang sangat besar, seperti terjadinya pendangkalan, terganggunya jalur lalu lintas, rusaknya lahan pertanian, permukiman, jembatan, saluran irigasi dan prasarana fisik lainnya. Longsor lahan menjadi bencana dengan kejadian terbanyak selama 2016 di wilayah Kabupaten Malang. Berdasarkan pengamatan lapangan Kecamatan Dau merupakan salah satu wilayah yang termasuk dalam rawan bencana longsor lahan. Penelitian tentang longsor di Dau belum banyak dilakukan sehingga dibutuhkan lebih banyak penelitian. Penelitian dimaksudkan agar masyarakat dapat memanfaatkan hasil penelitian tersebut untuk lebih memahami konsep longsor dan mitigasi bencana khususnya longsor, sehingga dampak negatif dari bencana tersebt dapat dihindari. Penelitian ini merupakan penelitian survei dengan observasi dan pengukuran di lapangan. Metode yang dipakai dalam penentuan tingkat daerah rawan longsor lahan di daerah Kecamatan Dau dengan cara kualitatif (menafsirkan kondisi geologi, geomorfologi, dan curah hujan dengan data primer maupun sekunder) dan cara kuantitatif (pengharkatan). Hasil penelitian Wilayah Kecamatan Dau yang memiliki potensi bahaya longsor lahan pada tingkat sangat rawan adalah Desa Kucur, Petungsewu dan Selorejo dengan prosentase luas 25.41%.
FAKTOR-FAKTOR YANG MEMPENGARUHI PENGAMBILAN KEPUTUSAN BERMIGRASI MASYARAKAT MADURA KE KELURAHAN BURING KECAMATAN KEDUNG KANDANG KOTA MALANG TAHUN 2017
Authors: Tyas Ratri Ning , Triwahyudianto Triwahyudianto
Published: August 2019

Tujuan penelitian ini adalah untuk mengetahui lebih dalam alasan migran Madura bermigrasi ke Kelurahan Buring Kota Malang dengan melihat dari faktor pendorong dan penarik.Teknik pengumpulan data menggunakan observasi, wawancara dan data dokumentasi. Analisis data menggunakan model analisis kualitatif untuk keabsahan temuan menggunakan triangulasi. Temuan penelitian bahwa sejarah migran bisa sampai di Buring karena di Madura lahannya panas dan kurang subur sehingga. Ada  6 faktor pendorong yang menyebabkan Madura bermigrasi ke Kota Malang yaitu: kendala pengolahan lahan pertanian, kondisi ekonomi, pendidikan rendah, sarana dan prasarana pendidikan yang kurang memadai, tidak cocok dengan budaya daerah asal,  lapangan pekerjaan terbatas. Terdapat 4 faktor penarik dari daerah tujuan yang menarik masyarakat Madura untuk melakukan migrasi yaitu: mendapat pekerjaan yang lebih baik, sarana kenyamanan, kesempatan membuka lapangan pekerjaan, aktivitas kota besar. Dalam pengambilan  keputusan yang dilakukan migran ada 3 yaitu keputusan diri sendiri, keputusan orang lain dan keputusan keluarga inti.