bluuebunny/crossref_metadata_2025 huggingface dataset:
Mechanical properties of atherosclerotic plaques, caps and walls of arterial vessels: a mobile test bench experiments
Authors:   Saratov State University, Dol Aleksandr
Published: December 2023

Within the framework of this study, a methodology and a prototype of a test bench for conducting experiments on compression of biological tissue samples have been developed. The test bench for the implementation of the technique consists of high–precision scales (measuring accuracy up to 0.01 g, maximum weight - 5 kg), an electronic caliper (measuring accuracy up to 0.01 mm) with 3D-printer pads that are attached to grips, as well as video cameras. Thanks to such a mobile stand, it was possible to conduct a series of experiments (a total of 99 tests) to determine the Young's modulus of atherosclerotic plaques and areas of vascular walls removed from the body no later than a few hours. This made it possible to collect a database of the mechanical characteristics of the plaques as close as possible to the real properties. In addition, regression dependences were constructed between the Hounsfield numbers corresponding to dense atherosclerotic deposits discernible on a CT scan and the Young modules obtained during experiments. Such dependencies will further allow determining the mechanical properties of plaques in vivo based on computed tomography data. The technique was verified by mechanical experiments on the universal testing machine Instron 3342 and on a mobile test bench on samples of hard (with pronounced calcification) and soft plaques. 7 experiments were conducted for each type of samples. The results differed by no more than 4.3 % for soft plaques and no more than 9.5 % for hard plaques. To test the inter-expert reliability of the methodology, a number of experiments were conducted with the involvement of two independent participants. Each of the three mobile stand operators performed 5 tests on soft rubber samples. The study of inter-expert reliability allowed us to show the independence of the methodology from the skills and qualifications of the operator.
Obraz Małopolski Wschodniej na łamach „Gazety Gdańskiej” – dziennika Polaków w Wolnym Mieście Gdańsku
Authors: Semków Piotr
Published: December 2023

In 1919, the Free City of Danzig was estabilished, as quasi-state inhabited mostly by people identifying themselves as Germans. The Polish population in this area was a minority that quite vigorously manifested ties with Poland. The Polonia of Gdansk (called the Polish minority ) had a popular daily paper in Gdansk – “Gazeta Gdańska”, publishing, among other things, news from Poland. Mainly political issues and issues related to Polish-German relations prevailed. Eastern Lesser Poland was an area too remote for the magazine to devote much attention to it.
„Podejrzani, lecz niewinni”. Wybrane śledztwa przeciwko Polakom w Ukraińskiej Socjalistycznej Republice Radzieckiej w latach 1937–1938, zakończone uniewinnieniem
Authors: Olechowski Piotr
Published: December 2023

The article is devoted to a comparative analysis of three cases of investigations conducted against Soviet citizens of Polish nationality, residing in the area “beyond the Zbrucz”. Cases of people from three different districts of the then Ukrainian SSR (Kamenets-Podilskyi, Vinnytsia and Odessa), which ended in acquittal, were deliberately selected for the analysis. Such trials resulted in the regaining of freedom by the suspects in only 3% of cases (so they concerned about four thousand people). The text contains an analysis of the entire investigation procedure – from issuing a decision to detain the suspect, through his arrest, taking him to a place of detention, interrogating both the detainee and witnesses, to issuing and justifying the decision to end the investigation and release the suspect.
O Lwowie inaczej – refleksje wokół pracy Zoriany Czajkowskiej Literackie topografie Lwowa. Szkice komparatystyczne, Wydawnictwo Uniwersytetu Śląskiego, Katowice 2021, ss. 268
Authors: Michliński Rafał
Published: December 2023

The history of Lviv, especially in the twentieth century, has caused Poles, Ukrainians, and also Russians to speak of the city as “theirs”. The national changes that occurred in Lviv as a result of World War II: the forced exodus of Poles (and the perpetuation of the myth of the city as Semper Fidelis), the Sovietisation of the city, and the subsequent incorporation of the city into the independent Ukrainian state, were all reflected in the work of writers of all three nationalities. The purpose of this article is to discuss Zoriana Tchaikovska’s work Literary Topographies of Lviv. Comparative sketches.
Characteristics of Anorexia Prevention Programmes. A Systematic Review
Authors:   University of Warmia and Mazury in Olsztyn, Korsak Emilia
Published: December 2023

This study aimed to review the literature on anorexia prevention programmes targeting the general population and populations at risk and to describe the programmes selected for the review. Methods: The review was conducted under the PRISMA guidelines. The following digital databases were explored: PsychINFO, PubMed, ScienceDirect, Scopus, and Web of Science. 412 records, including 92 full-length research articles, were critically analysed. Fourteen studies that met all inclusion criteria were ultimately included in the analysis. Results: Most studies described prevention programmes for adolescents or young adults. The majority of the reviewed programmes targeted girls and young women. General and selective prevention programmes were the predominant types of interventions. The evaluated programmes differed considerably in content, modality, and duration. All of the reviewed studies have been published in the last 18 years. Conclusions: Further research is needed to develop anorexia prevention programmes that are more effective, deliver more lasting outcomes, and can be applied in various populations. Methods supporting the broad implementation of such programmes should also be identified.
Analysis of Relationships between the Personality Traits and Value Preferences in a Polish Early Adolescent Sample. Do Gender and Age Play a Role?
Authors:   Jan Kochanowski University of Kielce, Łubianka Beata , Filipiak Sara ,   Maria Curie-Skłodowska University in Lublin
Published: December 2023

This paper presents an analysis of the personality traits and value preferences of Polish early adolescent students. Participants were 775 adolescents between 12-14 years (53% girls; Mage= 13.01; SD= 0.81), who completed two surveys: Picture-Based Personality Survey for Children and PictureBased Value Survey for Children. Fourteen-year-old adolescents preferred more Power values and less Tradition and Conformity values than 12- and 13-year-olds. They were also less open to experience and conscientious than their younger counterparts. 14-year-old girls had a stronger preference for Power and Achievement values and a weaker preference for Conformity values than 12-year-old girls. 14-year-old boys preferred more Traditional values than 12-year-old boys. Both 14-year-old girls and boys were less conscientious than the younger adolescents. A regression analysis with an interaction effect indicated that each age group had different relationships between gender and personality traits and their interactions with the particular value categories. The results are discussed in the context of possible practical rearing influence aimed at supporting young] preferred values and personality development in the context of education.
Reception of the Works by the Provencal Troubadours in E. Pound’s Poem The Cantos
Authors:   Perm State University, Bratukhina Liudmila V.
Published: December 2023

The article examines one of the parts of E. Pound's poem "The Cantos", which most fully reflected the American author's almost professional interest in the epoch and the works of the troubadours of Provence. The text of Canto VI traces various aspects of the reception of the culture of the Provençal poets: references to their works, including in the original language and in the form of stylizations; information from the legendary biographies of the most famous troubadours; images of historical figures of the epoch. The special role of the image of Eleanor of Aquitaine, the connecting mention of Provencal culture in Pound's text, is emphasized. Individual images and poetic texts of the troubadours are considered in the context of their correlation with Dante's "Divine Comedy". Attention is also paid to the images of ancient mythology and literature, compared in the text of Canto VI with the plots of the Provencal courtly love. The conclusion is made about the ambivalence of the understanding of love revealed by Pound through the reception of the troubadours' works.
Female Voice in German Fantasy for Teenagers “Tintentriologie” by Cornelia Funke
Authors:   Saratov State Conservatory named after L.V. Sobinov, Ivanova Elizaveta A.
Published: December 2023

The “Tintentrilogie” by Cornelia Funke is meant for teenagers, but includes subjects interesting also for an adult, such as the role of women in the society. Funke uses a traditional quasi-medieval fantasy world to address the problem of women in patriarchal society and in epic fantasy. This world is a creation of one of the characters, which makes it evident that the problem of misogyny still exists in the modern days too. The female characters of Funke deny such attitude toward them and play crucial roles in the plot.
“The Overlap of Myth and History”: Scottish Identity through Walter Scott to James Robertson in the Testament of Hideon Mack
Authors:   Perm State University, Lapina Evgeniia V.
Published: December 2023

The aim of this paper is to look at the works of Walter Scott and James Robertson through the lens of Scottish identity representation, and study Scott´s influence on The Testament of Gideon Mack by Robertson. The work takes a postcolonial approach to conceptualizing national identity. Scott´s influence on Robertson´s novel can be traced at different levels. Gérard Genette´s theory of transtextuality is used to discover all types of literary dialogue between the two authors. The analysis of The Testament of Gideon Mack is performed with the purpose of identifying the echoes and connections with Scott, on the one hand, and Robertson´s original techniques of portraying Scottish identity, on the other.
From Homer to Virgil: Interpretations of Achilles’s Image in Ascient Literature
Authors:   Perm State University, Manzhula Oksana V.
Published: December 2023

In the article it is made an attempt to analyze the variants of Achilles' image interpretation in the Ancient Greek and Roman literature. The author considers a number of works based on the plot of the Trojan War. The author notes the features typical for the given literary epoch, tendencies of representation of an ideal of heroism and courage embodied in the image of an ancient Greek hero, their importance and influence on the conception of the work is revealed. The author considers the tendencies of the image of the ancient hero depending on the requirements of the epoch.
Polyvariance of the Exegetic Hypotheses of Clement of Alexandria
Authors:   Perm State University, Bratukhin Aleksandr Yu.
Published: December 2023

Clement of Alexandria often offers several meanings for this or that number, fact, biblical verse. Two approaches can be distinguished in the presentation by this author of various options for understanding texts. In the first case, he gives several true, from his point of view, interpretations, in the second case, several probable interpretations. In the first case, apparently, we are dealing with a presentation by him of the previous oral tradition. In the second case, we have the contribution of Clement himself to this tradition, his own, author's interpretations, introduced by the words τάχα μέν, τάχα δὲ καί, ἤδη δὲ καί κτλ or optative.
Metaphorization of the Identity Crisis oa an Emigrant in Andreï Makine’s Novel “The Life of an Unknowm Man”
Authors:   Lomonosov Moscow State University, Teplyakova Anastasia B.
Published: December 2023

The article presents an analysis of the novel “The Life of an Unknown Man” by Andreï Makine from the metaphorical perspective of the identity crisis of an emigrant. Conceptual metaphors that reveal stereotypical ideas of emigration, motherland and the identity of an emigrant are specified in structural metaphors that create new concepts. These concepts implement a transition from the the positive image of Russia to a negative one as well as a total change of an emigrant’s idea of herself. The initial ontological metaphorical representation of an emigrant makes transition from a geographical concept to a time concept.
Intertext in E. Pound’s Poem The Cantos: Literary Sources in the Images of the Other World
Authors:   Perm State University, Bratukhina Liudmila V.
Published: December 2023

The article examines a fragment of Canto XVI from The Cantos in the aspect of intertectuality. The author of the article examines the mention in the work of E. Pound of personalities – D. Alighieri, Blessed Augustine W. Blake – whose works are somehow connected with the theme of the afterlife. The borrowing of images and ideas from their works is analyzed, along with Virgil's "Aeneid", allusions to the VI book of which are also contained in the lines under study. The influence of these works on the general concept of the afterlife in Pound's poem is noted, as well as the opposition of the traditional hierarchical system of the other world, reflected in Dante's work, and Blake's pre-romantic fantasy connecting the images of Hell and Paradise.
The Literary Features of Pat Barker’s Novel “The Silence of the Girls”
Authors:   Perm State University, Manzhula Oksana V.
Published: December 2023

The article attempts to analyse the literary features of the novel “The Silence of the Girls” by English writer Pat Barker as an "anti-Iliad". The author considers which works form the basis of the plot of Barker's novel. The features that oppose the novel to the "Iliad" and Euripides' tragedy "The Trojans" are noted.
The Patristic Pre-Eternal Council in the Literature of the XIII–XXI centuries
Authors:   Perm State University, Bratukhin Aleksandr Yu.
Published: December 2023

The article discusses three options for understanding the term “ Council” by the Church Fathers and secular poets who echoed them. Maximus the Confessor, John of Damascus, Thomas Aquinas, Dante, G. R. Derzhavin conceived this “Council” as an eternal plan for the creation and salvation of the world. Athanasius the Great and Milton spoke of the Son’s consent to atone for Adam's sin. Filaret of Moscow interprets the “Eternal Council” as a meeting of the Persons of the Trinity. Attention is focused on the word game κατὰ τὴν βουλὴν… πρὸ καταβολῆς κόσμου “according to the Council… before the creation of the world” from the Epistle to the Ephesians, which is hinted at by Eusebius of Caesarea, and it is noted that the use of the phrase “Eternal Council” is typical for the authors of Greek culture.
What Contemporaries Wrote to the Editorial Board: Factor of Public Initiative During the Years of Perestroika (Based on Perm Newspapers)
Authors:   Perm State University, Ekhlakova A. R.
Published: December 2023

The letters in the media largely refl ected the interest of citizens in the current social and political life. A striking example is the topic of initiatives responding to the challenges of modernity and the reaction to the «perestroika» project. Basing on the analysis of archival materials of the editorial offi ces of two major Perm periodicals – “Vechernyaya Perm” (“Evening Perm”) and “Molodaya Gvardia” (“Youth Guard”) — the letters of citizens devoted to the ongoing changes were studied. Initially, in the mid-1980s most of the addressees tried to consider the current situation and evaluate it, and as well they suggested their projects for «restructuring» the state and changing legislation. In fact, a lot of letters contained references not just to the program, but also to the word ‘perestroika’ itself. The authors assessed the process of restructuring in various aspects of life: from political processes to communal life. In their letters to the editorial offi ces of the Perm media, the addressees presented themselves, described problems and initiatives, used argumentation techniques, formulated their requests, while perestroika served not only as a context, but also as a tool for promoting initiatives.
VOOPIK Arkhangelsk Regional Branch Establishment and the Solovetsky MuseumReserve Organization: Historical Parallels
Authors:   Northern (Arctic) Federal University named after M.V. Lomonosov, Mazilova E. A. ,   Arkhangelsk Lore Museum
Published: December 2023

The time of establishment of the VOOPIIK regional branch in Arkhangelsk region coincides with an active discussion of the problem of preserving the historical and cultural heritage of the Solovetsky Archipelago. In 1967, a museum-reserve was established on the islands as an attempt to museumify and preserve architectural monuments. In parallel, conservation and restoration works were being carried out, which over time started to be funded at the expense of the VOOPIIK organization. Discussions around the Solovetsky monuments continued in the society, the tourist fl ow to the islands was increasing. It is no coincidence that the same people were active participants in the “Solovetsky question” and the regional branch of the VOOPIIK. What additional tools did membership in the mass movement for the protection of monuments provide for the promotion of their initiatives? What is the role of the VOOPIIK in the preservation and development of the territory of the Solovetsky Archipelago?
Patient and Surgeon’s Concerns with Post-Mastectomy Nipple Reconstruction: An Alternative to Traditional Nipple Reconstruction
Authors:   MedSurgPI LLC, 3700 Lark Farm Road, Franklinton, NC 27525, USA, Klein Gerald L. , Morgan Roger ,   MedSurgPI LLC, 3700 Lark Farm Road, Franklinton, NC 27525, USA, Heim William ,   BioAesthetics Corporation, 6 Davis Drive, Research Triangle Park, NC 27709, USA, Pashos Nicholas ,   BioAesthetics Corporation, 6 Davis Drive, Research Triangle Park, NC 27709, USA
Published: December 2023

Aims The aim of this paper is to determine what women who undergo reconstructive surgery after mastectomy (due to breast cancer) are seeking. It also answers the question, how plastic surgeons are attempting to fill this need. Methods A survey was undertaken of 84 plastic surgeons and 70 of their patients who underwent recent mastectomy and reconstruction surgery. All the material was deidentified before analysis. Results The majority of the women wanted their breasts and nipples to be natural and have the same appearance (or sometimes to be more attractive) or similar appearance. Conclusion Women undergoing this type of surgery frequently develop a decreased quality-of-life (QoL) which also affects their feeling of femininity, sexuality, and psychological well-being. The post-surgery time period and the additional necessary treatments are extremely stressful events. The importance of their breast post-operative aesthetics correlated with their self-esteem and body image. It is important for plastic surgeons to take these factors into consideration, when planning their reconstructive surgery
Emergency Department Diagnosis and Management of Superior Vena Cava Syndrome Secondary to Hodgkin’s Lymphoma: Case Report and Limited Literature Review of Emergency Department Management
Authors:   Department of Emergency Medicine, University of South Alabama, 307 N University Blvd, Mobile, AL 36688, USA, Henning Paul R. , Mellick Larry B. ,   Department of Emergency Medicine, University of South Alabama, 307 N University Blvd, Mobile, AL 36688, USA
Published: December 2023

Superior vena cava (SVC) syndrome refers to the obstruction of blood through the SVC with limited case reports and literature reviews of its presentation and management. Here we discuss a 26-year-old male who presented with progressive chest pain and shortness of breath for 5-weeks. The exam showed facial and neck plethora and distension of the veins in the neck and chest wall. This case discusses SVC syndrome due to external compression by Hodgkin’s Lymphoma. The diagnostic approach and the clinical management of superior vena syndrome are reviewed.
Thyrotoxic Periodic Paralysis after Surgery: A Case Report and Literature Review
Authors:   Department of Emergency Medicine, Jessa Hospital Hasselt, Hasselt, Belgium and Faculty of Medicine, University of Leuven, Leuven, Belgium, Wouters Cécile , Willems Melvin ,   Department of Emergency Medicine, Jessa Hospital Hasselt, Hasselt, Belgium, Mullens Annelies ,   Department of Endocrinology, Jessa Hospital Hasselt, Hasselt, Belgium, Meersman Agnes ,   Department of Emergency Medicine, Jessa Hospital Hasselt, Hasselt, Belgium
Published: December 2023

Thyrotoxic periodic paralysis (TPP) is a rare but potentially life-threatening muscle disease in a thyrotoxic patient. Due to the lack of knowledge, the diagnosis is easily missed. Diagnosis of TPP is made by documentation of hypokalemia and hyperthyroidism in acute generalized muscle weakness. Hypokalemia is caused by an intracellular shift of potassium because of an increased Na-K-ATPase pump activity and the inhibition of the inward rectifying potassium (Kir) channels. The initial treatment aims to treat potentially life-threatening cardiac arrhythmias caused by severe hypokalemia. This can be done with potassium substitution and nonselective beta-blockers, being aware of the potential of rebound hyperkaliemia. Definitive treatment consists of avoiding triggers and correcting the hyperthyroid state with antithyroid drugs, radioactive iodine, or thyroidectomy. Once patients are, permanently euthyroid complete remission of the paralytic attacks usually occurs. We present a case of a 37-year-old male with diffuse muscle weakness after surgery. A new diagnosis of thyrotoxic periodic paralysis was made in the emergency department. This review summarizes the epidemiology, clinical manifestations, pathogenesis, diagnostics, and treatment of TPP.
Erratum: Induced Pluripotent Stem Cells—Derived Stem Cells: A Promising Tool for Disease Modeling
Authors:   Department of Neurology, Henry Ford Hospital, Detroit 48202, MI, USA, Parasar Parveen
Published: December 2023

Unfortunately, there was an error in the original version of this article. The authors wish to delete the following sentence in the conclusion section: For example, in neurological rare metabolic disease, XALD, there is no genotype phenotype correction and due to inaccessibility of tissue samples, research presents caveats in discovery of biomarkers. This statement has been now corrected. The publisher and the author would like to apologise for any inconvenience caused to the readers. The change does not affect the scientific results. The corrected manuscript is updated and the original will remain online on the article webpage.
A Variant of Miller-Fisher Syndrome: A Case Report
Authors:   West Virginia United (WVU) Health System, Wheeling Hospital, Wheeling, WV 26003, USA, Campbel Emily F. , Ramesh Ramya ,   West Virginia United (WVU) Health System, Wheeling Hospital, Wheeling, WV 26003, USA, Malic Angelina ,   Medical University of Gdańsk, Gdańsk 80-210, Poland, Machani Sathyanarayana ,   West Virginia United (WVU) Health System, Wheeling Hospital, Wheeling, WV 26003, USA
Published: December 2023

This report describes the case of a patient who presented to the hospital with weakness, neuropathy, ataxia, and diplopia who was found to meet the criteria for Miller-Fisher syndrome but had symptoms, physical exam findings, and lab results inconsistent with typical Miller-Fisher syndrome and suggestive of a potential variant who experienced only a partial response to typical Guillain-Barré syndrome treatment.
Mental Health of Audiologists and Speech Language Pathologists in India during COVID-19: A Survey
Authors:   Jan Sewa Hospital, Dr. S S Tantia Medical College Hospital and Research Center, Sri Ganganagar, Rajasthan 335002, India and Faculty of Medical Sciences, Tanita University, Sri Ganganagar, Rajasthan 335002, India, Sanju Himanshu K. , Lohani Ankit K. ,   All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110608, India, Kumar Mahesh ,   Jan Sewa Hospital, Dr. S S Tantia Medical College Hospital and Research Center, Sri Ganganagar, Rajasthan 335002, India and Faculty of Medical Sciences, Tanita University, Sri Ganganagar, Rajasthan 335002, India
Published: December 2023

Introduction The World Health Organization (WHO) declared coronavirus disease-2019 (COVID-19), the most current coronavirus epidemic, a global pandemic on March 11, 2020. Healthcare personnel were significantly impacted by social isolation regulations and the pandemic. The purpose of the present study was to assess the impact of the COVID-19 pandemic on speech-language pathologists’ and audiologists’ mental health in India. Methods In order to meet the objectives of the current study, the General Health Questionnaire (GHQ-12) was utilized as a screening tool for psychological problems faced by Indian audiologists and speech-language pathologists. The poll gathered replies from 153 audiologists and speech-language pathologists working in India. Results The results of the current study showed that 51.80% of audiologists and speech-language pathologists experienced stress. Between 10 and 15% of audiologists and speech-language pathologists, have trouble focusing, making decisions, and dealing with challenges. Fifteen to twenty-five percent (15-25%) of professionals struggle to contribute meaningfully beyond obstacles are unable to engage in daily activities, lose confidence, and feel unworthy. Conclusion According to the findings of the current study, 30-50% of audiologists and speech-language pathologists in India experienced poor mental health during the COVID-19 outbreak. The current study showed how crucial it was to provide psychological assistance and treatment for the workforce of audiologists and speech-language pathologists throughout subsequent COVID-19 pandemic waves.
Rotational Thromboelastometry: Enhancing Hemostasis Monitoring in Anesthesia
Authors:   Tawam Hospital, Tawam, Abu Dhabi, UAE, Modi Girishkumar , Kumar Vijay ,   Tawam Hospital, Tawam, Abu Dhabi, UAE, Munagala Nagaraju ,   Tawam Hospital, Tawam, Abu Dhabi, UAE
Published: December 2023

Rotational thromboelastometry (ROTEM) is a viscoelastic point-of-care coagulation test that measures the dynamics of clot formation and lysis in whole blood samples. A cylindrical shaft that oscillates while passing through a tiny amount of blood is used in the procedure. Blood exerts increasing pressure on the shaft as it thickens into a clot. We can track the strength of the forming clot over time by measuring this resistance. ROTEM® can provide valuable information about the coagulation status of patients who are at risk of bleeding or thrombosis in various peri-operative settings, such as trauma, obstetrics, cardiac surgery, liver transplantation, and major orthopedic and vascular surgeries. In addition, it can aid in the diagnosis and treatment of peri-operative coagulopathy, reduce unneeded transfusions, and enhance patient outcomes.
Immunofluorescence on Fresh Frozen Kidney Tissue - Validation of Antibodies v2
Authors: Brewer Maya , Zhu Yuantee , Clothier Kelly , Spraggins Jeff , De Caestecker Mark
Published: December 2023

We describe the procedure for immunofluorescence on human kidney tissue embedded in carboxymethylcellulose or low melting point gelatin, and the subsequent validation criteria used for the antibodies based on their colocalization and/or localization with other segment specific antibodies. We describe: a) primary antibody detection by indirect immunofluorescence using species-specific fluorescently conjugated secondary antibodies with minimal cross reactivity to other species antibodies being tested; b) antibody detection using commercially available or in-house fluorescently conjugated primary antibodies; c) our protocol for detecting biotinylated antibodies and lectins using streptavidin or neutravidin conjugated fluorophores after blocking endogenous biotins; and d) a sequential staining protocol that allows co-labeling of unconjugated and conjugated antibodies from the same species that minimizes binding of the secondary antibody to the fluorescently conjugated primary antibody. Finally, after image acquisition and image analysis using QuPath, we describe the steps we take to initially assess antibody staining (including evaluation of fluorescently conjugated primary antibodies, and steps that are taken if initial staining is negative), and the subsequent validation criteria we use for primary antibodies that show appropriate staining (i.e.: correct cellular segments, subcellular localization, kidney region etc.) that is based on co-localization with other antibodies, cell markers, and/or structures in the human kidney.
DoTA-seq V3 v1
Authors: not provided freeman.lan
Published: December 2023

This protocol describes the process of DoTA-seq generating a single cell sequencing library from a cell suspension. This workflow can be performed in two days, with the PCR step happening overnight. Before beginning this workflow make sure to have: 1. The necessary microfluidics devices prepared and ready to go 2. The multiplex DoTA-seq target primers validated to work together without generating large molecular weight primer dimers. Please read the publication for further details.
The Effect of Gamified and Blended Modules on English as a Foreign Language Learners’ Language Skills
Authors: GÜZEL Serhat , YILMAZ Cevdet
Published: December 2023

Gamification is among the trendiest topics in the context of English language teaching. Despite numerous studies on the impact of gamified language learning, further research is essential to comprehend its dynamics across diverse contexts. Therefore, this study aimed to explore high school language learners’ certain language skills after seven weeks of gamified and blended language learning experience. A mixed-method research design was employed to understand the impact of gamified content on learners’ reading, vocabulary, grammar, and writing skills. Students’ reading, vocabulary, and grammar skills were measured with proficiency tests administered before and after the intervention whereas their writing competence was investigated through grading their written assignments. In addition, learners’ opinions regarding the experience were collected to relate the statistical findings to qualitative data. As a result, it was found that the gamified learning experience improved language learners’ language skills and learner opinions explained these outcomes adequately.
On the Existence of Phonon Coherent States in Nanomaterials
Authors:   Peter the Great Saint-Petersburg Polytechnic University, Russia, Orlenko E.V. , Orlenko F.E. ,   Peter the Great Saint-Petersburg Polytechnic University, Russia
Published: December 2023

In our work we describe the energy transfer by thermal excitations with accounting a coherence in nanosized systems during heat removal. A general formalism of thermal conductivity by second quantization method is proposed with an account of both the usual phonon model of heat transfer and the formation of coherent Schrödinger states of the oscillator system. An exact general form of solution for a time-dependent problem with arbitrary initial conditions is analytically developed. It is shown that at certain ratios of constants characterizing the interaction of phonons with the electronic subsystem a heat flow does not decay with time in the crystal.
Issues of Psychological and Pedagogical Support of Professional Self-Determination of Minors with Deviant Behavior in the Works of Russian Psychologists
Authors: Smolenkova V.A. , Shpagina E.M.
Published: December 2023

The problem of professional self-determination of the personality of adolescents with deviant, including illegal behavior, is of interest to psychologists and educators, since it is the choice of profession and successful consolidation in professional activity that is an alternative to the criminal career of adolescents experiencing difficulties of socialization. The task of psychological and pedagogical support at this age is to consolidate a teenager’s interest in professional choice, to help comprehend the meaning of work in a life context. Psychological and pedagogical work with this category has its own characteristics. The article provides an analytical review of the theoretical foundations of psychological and pedagogical support of professional self-determination of adolescents prone to deviant, including illegal behavior.
Subjective Well-Being of Young People from Among Orphans in the Conditions of Transition to Independent Life
Authors: Oslon V.N. , Odintsova M.A. , Semya G.V. , Zaitsev G.O. , Kolesnikova U.V.
Published: December 2023

The article presents the results of a comparative study of the subjective well-being (hereinafter — SB) of students and graduates of various forms of life arrangement of orphans: an organization for orphans (hereinafter — o\o), a substitute family. As well as those who were returned after an unsuccessful family arrangement to an organization for orphans. It is shown that graduates, regardless of the group, in the conditions of transition to an independent life, the level of SB decreases, and the number of recorded stresses increases. The most frustrated group are graduates of substitute families. They are, in the terminology of A. Adler, are experiencing the “trauma of overthrow from the throne”. The most satisfied with life compared to others before graduation in independent life do not cope with difficulties, especially young men. Graduates of orphanages are the most prepared for independent life. If before graduation they rated their SB significantly lower compared to foster children, then in the post-international period they took leading positions among others. In the conditions of o\o, the students from the group of those returned from the family felt significantly less prosperous compared to others. In independent life, they have new opportunities, the level of self-esteem, satisfaction with security and relationships with relatives and friends increases. The article provides recommendations for post-international support of graduates.
Complicaciones en pacientes con catéter de hemodiálisis según sitio de inserción en hospital de referencia
Authors: Caballero-Torres Marlene Elizabeth , Alvarenga-Tanii Amy Fabiola , Ocampos-Mamani Cinthia Carolina , Zaputovich-Filippi Juan José , Cáceres-Santacruz Sandra Manuela
Published: December 2023

Introducción: Más de dos millones de personas en el mundo reciben tratamiento sustitutivo renal; la infección sanguínea representa una amenaza significativa, siendo la segunda causa de muerte en estos pacientes. La tasa de supervivencia depende en gran medida del tipo de acceso vascular utilizado. Objetivo: Determinar las complicaciones en pacientes con catéter de hemodiálisis en relación al sitio de inserción. Materiales y Métodos: Estudio de cohorte prospectivo, analítico, con medición de la frecuencia de complicaciones de pacientes con catéter de hemodiálisis a nivel yugular y femoral. Las variables se obtuvieron de los expedientes clínicos de pacientes internados ≥18 años. Resultados: Se incluyeron 203 pacientes, 66,01% masculinos; una edad media de 52 ± 15 años. 123 pacientes portaban catéter yugular y 80 pacientes, femoral. La curación se realizó cada 3 ± 5 días. La duración media de catéteres antes de signos de infección fue 4 ± 4 semanas en femorales y 9 ± 12 semanas en yugulares. Las bacterias gram positivas predominaron en los hemocultivos; aquellos con acceso femoral presentaron bacteriemia en mayor porcentaje. El cultivo de punta de catéter presentó una baja sensibilidad. Pacientes con catéter femoral presentaron mayor frecuencia de complicaciones. De las complicaciones infecciosas, la más frecuente fue el choque séptico en los portadores de catéteres femorales 57,50% vs los yugulares 4,88%. Otros: endocarditis, 7,32% en yugulares vs 2,50% en femorales; y finalmente la espondilodiscitis, con un 7,50% en femorales. La mortalidad fue mayor en aquellos con catéter femoral, 35% vs 8,94% en yugulares. Conclusión: Se ha evidenciado que el catéter femoral presenta mayor incidencia de complicaciones como choque séptico y bacteriemia, directamente relacionado con mayor tasa de mortalidad.
COMPARATIVE ASSESSMENT OF CYTOTOXICITY AND ACCUMULATION OF LITHIUM AND BORON IN SKIN MELANOMA CELLS IN VITRO
Authors: Kasatova A.I. , Taskaeva Yu.S. , Razumov I.A. , Taskaev S.Yu. , Bgatova N.P.
Published: December 2023

Boron neutron capture therapy (BNCT) is a binary radiation therapy modality based on the high capability of the non-radioactive isotope 10B to absorb thermal neutrons. The use of alternative isotope 6Li for lithium neutron capture therapy (LiNCT) may be a promising area in the treatment of oncological diseases, but at present the data on the possibilities of lithium accumulation in tumor cells are limited to some sporadic studies.
TUMOR GROWTH ADHESION
Authors: Bocharova O.A. , Karpova R.V. , Bocharov E.V. , Aksenov A.A. , Kucheryanu V.G.
Published: December 2023

The concept that the key mechanism of the tumor process is the disruption of adhesive interactions is based on the participation of local, general and central mechanisms.
Prevalence, patterns of clinical presentation, and the outcome of treatment of diabetes mellitus among paediatric patients in a tertiary care facility
Authors: Ashibogwu Ezinneamaka Maureen , Edeh Gabriel Chidera , Ekwebene Onyeka Chukwudalu , Obiekwe Sochima Johnmark , Chiekezie Chinonuju Franklin , Iheakanwa Oluchi , Abalihe Uchenna Onyedika , Anisiobi Promise Ugochukwu
Published: December 2023

Background: Diabetes mellitus is a multi-systemic disease condition characterized by elevated blood glucose level which can be due to relative or absolute deficiency of insulin secretion or action or a combination of both in humans including paediatric patients which disproves the thought that it is a disease of adults alone.
Methods: The study was a retrospective descriptive cross-sectional full population study that involved getting the total population of 7880 paediatric patients that presented to the hospital facility within 3-years (from January 2019-December 2021) and from the total population getting the patients diagnosed with diabetes mellitus. A well-structured proforma was used to collect the relevant data needed from the case files of the patients. Statistical data analysis was done with SPSS version 25.
Results: The study showed that out of 7880 paediatric patients that presented to the facility, 20 of them were diagnosed and treated for diabetes mellitus giving a prevalence of 0.25 per 100 patients. The paediatric patients diagnosed with diabetes mellitus were aged 8-18years; 11 females and 9 males. This study showed that about 75.0% of the paediatric patients with DM fully recovered following treatment and was subsequently discharged; however about 95% of these patients were lost to follow-up.
Conclusions: Adequate measures needs to be put in place to ensure that the management of these patients are highly optimal and does not constitute much financial burden to the caregivers, in order to improve compliance to treatment and hence reducing morbidity and mortality associated with the condition.
Effectiveness of sustained maximal inspiration along with transcutaneous electrical nerve stimulation in patients with malignant pleural effusion with intercostal drainage tube: a randomized controlled trial
Authors: Gunjal Sambhaji B. , Jain Vandana
Published: December 2023

Background: Malignant pleural effusion (MPE) is one of the most common causes of an exudative pleural effusion. It is the most common cause of a unilateral massive pleural effusion. Most MPE s are secondary to metastases to the pleura, most often from lung or breast cancer.  Medical management includes aspiration of fluid with the insertion of a chest tube, which may be necessary to relieve dyspnea. Hypoventilation does occur in certain areas of the lungs because of pain and muscle guarding after intercostal drainage tube (ICD) tube placements in pleural effusion. Therefore, it is important to emphasize pain management and expansion of affected areas of the lungs and chest wall. SMI is the basic maneuver of incentive spirometry and is mainly given to prevent atelectasis and lung collapse in postoperative patients. TENS is a method of producing an electro-analgesic effect and is effective in providing post-operative pain control.
Methods: The study design of the study was a randomized controlled trial. A total of 44 participants with a diagnosis of MPE with an intercostal drainage tube were included in this study. The study duration was 5 years with an intervention period of 2 weeks and the outcome measures were pulmonary functions and intercostal pain severity using the NRS Scale.
Results: There was a significant improvement in pulmonary functions in the control group and a highly significant improvement in pulmonary functions in the experimental group after 2 weeks of interventions and pain severity (NRS) was significantly reduced in the experimental group only (p<0.001)
Conclusions: This study concluded that sustained maximal inspiration (SMI) along with TENS significantly improves pulmonary functions and reduces pain at the site of ICD in patients with MPE.
Study of correlation between blood haemoglobin levels and blood groups in the age group 18-25 years
Authors: Pardeshi Amita
Published: December 2023

Background: Anemia is worldwide health problem. Medical students come from different geographical regions, socio-economic status and cultural backgrounds. Pernicious anemia occurred more frequently in A blood group males and females. This study was undertaken to find out correlation of hemoglobin with blood group in medical students.
Methods: A total of 150 healthy students were finally recruited for the study consisted of 79 males and 71 females. In this study, blood group was determined using glass slide method while hemoglobin concentration was estimated using Sahli’s method.
Results: Blood group O+ was the most common, followed by B+ blood group in our study. In this study 132 healthy students tested Rh+, whereas the remaining 18 tested Rh-.  In this study, students with hemoglobin concentration less than 10 gm/dl were taken as anemic. Total 40 students are anemic, out of 40, 28 females were anemic whereas only 12 males were found to be anemic. 36 students with Hb less than 10 gm/dl were Rh positive and 4 students Rh negative.
Conclusions: In this study, students with blood group B are more prone to anemia followed by blood group O; A and least is with blood group AB.
Role of height of an individual and low lying pubic tubercle as risk factors of inguinal hernia: case controlled study
Authors: Bhandary Disha , Amin Rachan , Shetty Ranjith
Published: December 2023

Background: Hernia is defined as abnormal protrusion of whole or a part of a viscus through the wall that contains it. Among all external abdominal hernias, inguinal hernia is one most typically encountered. Many factors are responsible for the formation of hernia. We intended to study the risk of inguinal hernia in low lying pubic tubercle.
Methods: The study was conducted on patients in AJIMS, India. It is a case-control study with 80 cases and 80 control meeting inclusion criteria, in all patients, following parameters SS line, ST line, height, weight was recorded and evaluated.
Results: The average SS value for case which was much above the average in control.ST value was higher case group than control group, and p<0.0001 which was significant. when it comes to the mean of (SS/ST ratio)/height was higher in the case group than control group. Results developed show majority of the subjects with a low-lying pubic tubercle were inguinal hernia patients.
Conclusions: Based on my study, interspinal distance (SS line) and pubo-spinal distance (ST line) are more in cases compared to control. Configuration of bony pelvis seems to be a major contributing factor in determining the risk of development of inguinal hernia as evidenced by the variations in ST length. This low-lying pubic tubercle is very important before selecting the patient for any surgical correction. So, the proper demonstration of anatomy of inguinal region is very important before selecting the surgical technique.
Knowledge, attitude and practices of pregnant women for antenatal care during COVID-19 pandemic
Authors: Singh Ajay K. , Goel Promila K. , Kaur Sukhmanpreet , Goel Vishal K.
Published: December 2023

Background: The antenatal care had suffered across the globe during COVID-19 pandemic. This study was undertaken to elicit knowledge, attitude and practices adopted by pregnant women for antenatal care during the pandemic.
Methods: A cross-sectional survey was undertaken (N=126) at a purposively selected community health center Nalagarh of Solan district in north India. Self-administered pilot tested standardized questionnaire was employed.
Results: 46 percent of women were in age group of 21-25 years and had secondary level of education. 60 percent were primigravida. 47 percent of pregnant women significantly undertook antenatal care from civil hospital and 33 percent availed these services from the public health facility of the level of Primary Health Centre or Community Health Centre, χ2 (1, N=126) =7.7, p=0.02. All pregnant women had taken complete antenatal care for four times and as per schedule. Only one tested positive for the disease COVID-19. Majority of the pregnant women studied were asymptomatic. The participants had the knowledge about symptoms of disease and COVID-19 appropriate behavior. About 25 percent also had difficulty in approaching the public health sector due to lack of accessible transportation. 18 and 33 percent of pregnant women suffered from stress and anxiety respectively. All undertook iron and folic acid along with tetanus prophylaxis. 21 and 18 percent practiced wearing of face mask and frequent hand washing with soap respectively.
Conclusions: COVID pandemic did not hinder antenatal care adopted by pregnant women. Lockdown and isolation were important perceived worrisome aspects of the disease.
Inguinal plasty and appendectomy as treatment for Amyand's hernia: case report and literature review
Authors: Blaz Zavala Rogelio A. , Uribe Elizabeth Martinez , Flores Garcia Alba E. , Calderon Uriel Cruz , Elizondo César Reyes
Published: December 2023

Amyand's hernia is described as the presence of the caecal appendix within the hernial sac of an incarcerated inguinal hernia. It was reported as an incidental finding in 1% of cases and with evidence of appendicitis in 0.1% of cases. The approach involves performing appendectomy and inguinal repair in the same surgical time, depending on the clinical scenario and the surgeon's decisions. We presented the case of a 76-year-old male patient with a diagnosis of Amyand's right inguinal hernia diagnosed during trans-operative right inguinal plasty.