bluuebunny/crossref_metadata_2025 huggingface dataset:
FOR DONATION, ORGANISATION, AND NATION: Muhammadiyah’s Charity Stamp Program, 1941-1942
Authors: Zara Muhammad Yuanda
Published: October 2024

Studies on Muhammadiyah’s charitable works mostly discuss the charitable institutions Muhammadiyah founded, such as hospitals and orphanages, and neglect one-off fundraising activities. This study examines Muhammadiyah’s strategies in promoting ‘Muhammadiyah charity stamps’ to the Netherlands Indies people in 1941. This study shows that although stamps are only small postal items, Muhammadiyah paid great attention to promoting and selling these stamps. It ran a well-organised and national-scale campaign, mobilising its network of branches and groups throughout the Indies. Muhammadiyah used all available campaign media, such as magazines, newspapers, pamphlets, pictures, songs and meetings. To maximise promotion, Muhammadiyah emphasised that buying these charity stamps meant giving donations that Allah would reward, supporting Muhammadiyah’s movements, and helping the welfare of the indigenous people. These charity stamps helped Muhammadiyah raise enormous funds and strengthened its reputation at home and abroad as a social movement that cared for the less fortunate. This study elucidates the largest and most successful one-off charitable fundraising effort, but so far still forgotten in the historiography of Indonesian Islam, which was carried out by an indigenous Muslim socio-religious organisation during the colonial period, using previously overlooked primary documents dating from 1941-1942.[Studi mengenai kiprah Muhammadiyah di bidang amal umumnya membahas tentang institusi amal yang didirikannya, seperti rumah sakit dan panti asuhan. Kegiatan pengumpulan dana yang sifatnya sekali waktu saja banyak diabaikan. Kajian ini membahas strategi Muhammadiyah dalam mempromosikan ‘prangko amal Muhammadiyah’ kepada masyarakat Hindia Belanda pada tahun 1941. Kajian ini menunjukkan bahwa walaupun prangko hanya berupa benda pos kecil, Muhammadiyah memberikan perhatian yang luar biasa untuk mempromosikan dan menjual prangko ini. Organisasi ini menjalankan kampanye yang rapi dan berskala nasional, dengan menggerakkan jaringan cabang dan rantingnya di seluruh Hindia. Muhammadiyah menggunakan segala macam media kampanye yang tersedia, seperti majalah, surat kabar, pamflet, gambar, nyanyian, dan pertemuan-pertemuan. Untuk memaksimalkan promosi, Muhammadiyah menekankan bahwa membeli prangko amal ini berarti melakukan amal yang berpahala, menyokong gerakan sosial Muhammadiyah, dan membantu menyejahterakan masyarakat pribumi. Prangko amal ini membantu Muhammadiyah mengumpulkan dana yang sangat besar dan memperkuat reputasinya di dalam dan luar negeri sebagai gerakan sosial yang menaruh perhatian pada mereka yang kurang beruntung. Kajian ini menerangkan tentang usaha pengumpulan dana amal sekali-waktu yang terbesar dan tersukses, namun sejauh ini masih terlupakan dalam historiografi Islam Indonesia, yang dilakukan suatu organisasi sosial-keagamaan Muslim pribumi pada masa kolonial, dengan menggunakan dokumen-dokumen primer yang berasal dari tahun 1941-1942.]
TAFSIR HIKAYATI AS A RESISTANCE HERMENEUTICS: Hikayat Prang Sabi’s Contribution to Holy War Literature and Quranic Studies
Authors: Fadhli Fadhli , Ichwan Moch Nur , Machasin M.
Published: October 2024

This article will elaborate on the model of interpreting the Quran in Hikayat Prang Sabi. Guided by the text by Teungku Chiek Pante Kulu, the author analyses the data by Hans Georg Gadamer’s ideas about “Preunderstanding”, “Fusion of Horizons”, and “Historical Consciousness”. This research shows that Hikayat Prang Sabi has introduced a unique model of interpreting the Quran by adopting hikayat instruments in Acehnese culture. The author identifies this interpretation model in this research with Tafsir Hikayati. Tafsir Hikayati has contributed to constructing the Acehnese’s resistance to Dutch colonialism by bringing together two very influential spirits in Acehnese society: religion and culture. Through Tafsir Hikayati, Teungku Chiek Pante Kulu constructs a “Resistance Hermeneutics” by interpreting Islamic religious texts (the Quran) using the Acehnese cultural language (hikayat). Combining these two spirits has helped the Acehnese people accept and capture the message of resistance conveyed by Hikayat Prang Sabi so that it succeeded in awakening the spirit of ideological struggle against Dutch colonialism.[Artikel ini mengelaborasi model penafsiran Al-Quran dalam Hikayat Prang Sabi. Dengan berpedoman pada teks karya Teungku Chiek Pante Kulu, penulis menginterpretasi data dengan meminjam gagasan Hans Georg Gadamer tentang “Pra-Pemahaman”, “Perpaduan Horizon (cakrawala)”, dan “Kesadaran (keterpengaruhan) sejarah”. Penelitian ini menunjukkan bahwa Hikayat Prang Sabi telah memperkenalkan model penafsiran Al-Quran yang khas dengan mengadopsi intrumen hikayat dalam kebudayaan Aceh. Dalam penelitian ini, penulis mengidentifikasi model penafsiran tersebut dengan istilah Tafsir Hikayati. Tafsir Hikayati telah berkontribusi dalam mengkontruksi perlawanan orang Aceh terhadap kolonialisme Belanda dengan mempertemukan dua spirit yang sangat berpengaruh dalam masyarakat Aceh: agama dan budaya. Melalui Tafsir Hikayati, Teungku Chiek Pante Kulu mengonstruksi tafsir perlawanan (resistance hermeneutics) dengan melakukan interpretasi teks keagamaan Islam (Al-Quran) menggunakan bahasa kebudayaan (hikayat) yang berkembang di Aceh. Perpaduan dua spirit tersebut telah membantu orang Aceh dalam menerima dan menangkap pesan perlawanan yang disampaikan oleh Hikayat Prang Sabi sehingga berhasil membangkitkan semangat perjuangan ideologis dalam melawan penjajahan Belanda.]
Islamic Faith as A Source of Coping with Work Stress
Authors: Sentürk Faruk Kerem , Isikan Selin
Published: October 2024

Many alternative strategies, mainly faith-based, have been used to cope with stress. The main purpose of this research is to understand the stress experienced by managers and the role of the Islamic faith in the process of coping. A qualitative phenomenological design was used, and 19 managers in the Düzce Organized Industrial Zone in Turkey were reached by snowball sampling method. Face-to-face and online interviews were conducted using a semi-structured interview form. The data were subjected to content analysis and coded using a mixed method, resulting in 282 codes grouped into 30 categories and six themes (perception of stress, sources of stress, consequences of stress, coping, place of Islam in life, Islamic coping). The study shows that the participants perceive stress as a process that can spread to all areas of life. Meanwhile, religious belief influences how an individual perceives stress and its consequences. The perception of stress also determines what type of coping strategies will be preferred. The author further argues that Islamic teachings deal with coping with stress in a more holistic way, covering both psychological and physiological dimensions. In addition, time management discipline triggered by Islamic rituals, such as prayers and other forms of worship, has a positive stress-regulating effect.[Sudah banyak strategi alternatif yang telah digunakan untuk mengatasi stres, terutama yang berbasis agama. Tujuan utama penelitian ini adalah untuk memahami stres yang dialami oleh para manajer perusahaan dan peran ajaran Islam dalam proses penanggulangan stres. Dengan desain fenomenologis kualitatif, penelitian ini melibatkan 19 manajer di Kawasan Industri Terorganisasi Duzce di Turki, melalui snowball sampling. Wawancara tatap muka dan daring dilakukan dengan menggunakan panduan wawancara semi-terstruktur. Data yang diperoleh kemudian dikaji dengan analisis isi dan mixed-method, yang menghasilkan 282 kode yang dikelompokkan ke dalam 30 kategori dan enam tema (persepsi stres, sumber stres, konsekuensi stres, penanggulangan, posisi ajaran Islam, penanggulangan Islami). Studi ini menunjukkan bahwa para peserta menganggap stres sebagai suatu proses yang dapat menyebar ke semua bidang kehidupan. Sementara itu, keyakinan agama memengaruhi cara seorang individu memandang stres dengan segala konsekuensinya. Persepsi terhadap stres juga menentukan jenis strategi penanggulangan yang akan dipilih. Penulis juga berpendapat bahwa ajaran Islam menangani stres dengan cara yang lebih holistik, yang mencakup dimensi psikologis dan fisiologis. Selain itu, disiplin manajemen waktu yang dipicu oleh ritual-ritual Islam, seperti salat dan bentuk-bentuk ibadah lainnya, memiliki efek positif dalam mengatur stres.]
Penilaian Tingkat Kecemasan pada Lanjut Usia dengan Arthritis di Kota Banda Aceh
Authors: Fazillah Abrar , Nurhasanah Nurhasanah , Febriana Dara
Published: October 2024

Gangguan afektif komorbid seperti depresi, stress, kecemasan serta penggunaan obat-obatan pada lansia dengan arthritis rheumatoid dianggap menjadi faktor yang bisa mempengaruhi kecemasan pada lansia. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana tingkat kecemasan pada lanjut usia dengan arthritis di Kota Banda Aceh. Penelitian ini menggunakan desain deskriptif eksploratif dengan pendekatan cross-sectional study. Sampel dalam penelitian ini adalah lansia di Kecamatan Baiturrahman yang berjumlah 100 orang dan penelitian ini menggunakan Teknik Accidental Sampling. Instrumen yang digunakan Geriatric Anxiety Scale (GAS). Hasil menunjukkan bahwa terdapat 43 responden (43,0%) mengaku tidak pernah mengalami kecemasan, 32 responden (32,0%) dinyatakan mengalami kecemasan ringan, 8 responden (8,0%) memiliki tingkat kecemasan tingkat sedang dan 17 responden (17,0%) mengalami kecemasan berat yang diakibat dari arthritis yang dideritanya. Penelitian ini diharapkan mampu menjadi masukan bagi masyarakat luas. Kemudian untuk masyarakat lebih memahami dan memiliki wawasan untuk selalu menjaga pola makan, olahraga teratur, menjaga kalsium tetap terpenuhi selalu mengontrol kadar asam urat dalam tubuh dan juga memeriksa sesuatu yang tidak wajar apabila menyebabkan nyeri sendi ke pelayanan kesehatan terdekat. Sehingga dapat mencegah komplikasi yang nanti nya bisa saja terjadi.
Efficacy of nano urea in replacing conventional nitrogen application and its effect on fruit quality in strawberry
Authors: Shaifali  , Manish Bakshi  , Meenakshi Rana  , Nidhi Chauhan  , Jatinder Singh Dhaliwal  , Sreethu S  , Rajeev Kumar Gupta
Published: October 2024

In a study conducted on strawberry cv. Winter Dawn, the combined application of nano urea and Azotobacter was investigated for its impact on quality and biochemical attributes under protected cultivation. The findings revealed a noteworthy response of strawberry plants to foliar nano applications compared to conventional soil application of urea. Despite the lower nitrogen dosage associated with nanoparticle supplementation, strawberries with nanoparticles exhibited significant improvements in qualitative and biochemical parameters. These results underscore the potential of urea nanoparticles as a viable nitrogen source, advocating for alternative approaches to nitrogen fertilization. By fine-tuning the dosage ratio, this strategy shows promise in fostering a more environmentally friendly, sustainable and modern method for cultivating strawberries. The enhanced quality and biochemical attributes observed in strawberries treated with nano urea highlight the efficacy of this innovative approach in optimizing plant growth and productivity. Furthermore, the utilization of nano urea in combination with Azotobacter demonstrates synergistic effects, potentially enhancing nutrient uptake and utilization efficiency in plants. This holistic approach improves crop quality and reduces the environmental impact associated with traditional fertilization methods. In conclusion, the findings of this study support the adoption of urea nanoparticles as a valuable tool in strawberry cultivation, offering a pathway towards sustainable agricultural practices. Future research efforts should focus on optimizing application protocols and assessing long-term effects to fully exploit the potential of nano-based fertilizers for strawberry.
HPLC analysis and antimicrobial activity of Vitex altissima leaves extracts
Authors: Ajinza A  , Arun A Rauf  , Boby T Edwin
Published: October 2024

The exploration of ethnomedicinal plants for phytochemical and pharmacological properties is crucial for developing novel therapeutics for chronic diseases. Vitex altissima, known as the Peacock chaste tree, is a significant member of the Verbenaceae family, is widely utilized in traditional medicine. This study investigates the phytochemical composition and antibacterial properties of V. altissima, a plant recognized for its medicinal use by various indigenous communities, including the Malayali tribes of Servarayan hills. The study involved extracting phytochemicals from the leaves of V. altissima using hexane, ethyl acetate and methanol through soxhlet extraction. The extracts were analyzed for secondary metabolites, including carbohydrates, proteins, amino acids, steroids, glycosides, alkaloids, tannins, phenolics, flavonoids, terpenoids, saponins, anthraquinones, oils and resins, diterpenes, phlobatannins and coumarins. Quantitative assessments of phenolic compounds, flavonoids and alkaloids were performed. Column chromatography was employed to fractionate the methanolic extract, resulting in 12 distinct fractions. These fractions were screened for antibacterial activity against E. coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Streptococcus mutans and Staphylococcus aureus using the agar well diffusion method. The minimal inhibitory concentration (MIC) was determined through a 2-fold serial dilution technique. High-performance liquid chromatography (HPLC) was utilized to identify the polyphenolic compounds responsible for antibacterial activity. Phytochemical screening revealed a diverse array of bioactive compounds in the extracts, with methanol extracts showing the highest total phenolic content (218 ± 7.21 mg GAE/g of extract) and significant antibacterial activity. The ethyl acetate extract exhibited the highest total flavonoid content (40.67 ± 6.65 mg QE/g of extract). Among the fractions, the column fraction from the chloroform-methanol gradient (VACF) demonstrated superior antimicrobial activity, particularly against S. mutans and P. aureginosa. The MIC values for VACF were 427 µg/mL for P. aeruginosa and 400 µg/mL for S. aureus, indicating potent antibacterial properties. HPLC analysis identified key polyphenolic compounds, including p-coumaric acid, ferulic acid and elagic acid, as the primary contributors to the antibacterial activity. The presence of these compounds aligns with the observed antimicrobial efficacy and highlights the potential of V. altissima extracts as a source of natural antibacterial agents.
Advancements in nanobiochar for environmental remediation: A comprehensive review
Authors: Rajarathinam Deepshikaa  , Mohan Prasanthrajan  , Christopher Sharmila Rahale  , Subramani Umesh Kanna  , Ramasamy Mahendiran  , Kalappan Thangamuthu Parthiban  , Vellingiri Geethalakshmi
Published: October 2024

This study delves into the diverse domain of biochar and its nano-variant, discussing their definitions, synthesis methods, properties and applications. Biochar, produced from various raw materials through different synthesis techniques, possesses unique characteristics that make it valuable for a wide range of uses. Nanobiochar, a new derivative, offers improved properties due to its nano-scale structure, enabling advanced applications. The study examines the physical and chemical attributes, surface area and pore structure of nanobiochar, along with methods for its functionalization and modifications. Synthesis techniques for nanobiochar are analyzed and compared with those for biochar and activated carbon. The versatility of nanobiochar is highlighted in its environmental, agricultural and energy applications, especially in water and soil purification, soil enhancement and energy storage. The environmental impact and safety considerations are also discussed, including eco-toxicity assessment, fate and transport in the environment and regulatory aspects. Additionally, the study addresses challenges, future perspectives, emerging trends and potential breakthroughs in nanobiochar research, emphasizing the need for ongoing exploration and innovation. In conclusion, nanobiochar shows great potential as a sustainable and versatile material with extensive applications, but it requires careful consideration of environmental and safety issues.
Русские катойконимы глазами носителей языка: конкуренция символических ценностей
Authors: Ахметова Мария Вячеславовна
Published: October 2024

В статье ставится вопрос, почему внутри локальных сообществ ведется полемика о вариантных названиях жителей (катойконимах) и в чем причины значимости той или иной аргументации участников дискуссий. Рассматриваемый материал лежит в поле языковых установок и идеологий; обыденных представлений носителей языка о языке и локальной идентичности. Выявляются принципы конструирования представлений о релевантных и нерелевантных катойконимах, актуализируемых в рамках дискурса нормативности, дискурса локальности и дискурса традиционности. Этим дискурсам соответствуют три престижных ресурса, или символических ценности (грамотность, локальная специфичность и привычность), которые для носителей языка определяют выбор того или иного варианта. Рассматриваются два кейса: дискуссии о релевантности/нерелевантности вариантных катойконимов в Старой Руссе и Тамбове; демонстрируется различное соотношение в этих дискуссиях указанных конкурирующих ценностей.
Universalizing the particulars: neoliberalizing English language teaching (ELT) through outcome-based education (OBE)
Authors: Memon Talha , Shah Waqar Ali
Published: October 2024

Universities, once regarded as places for producing organic intellectuals and critical thinkers, now are targets of neoliberalism, where managerialist discourses and lexis are dominant in various forms. Students and teachers are transformed into entrepreneurs, consumers and customers through such discourse and lexis. As a neoliberal variant used in education today, outcome-based education (OBE) – focus of the present study – can be viewed as one such discursive attempt on the part of the universities with an aim to perpetuate neoliberal market rationality. Through in-depth semi-structured interviews with teachers at engineering universities in Pakistan, this study examines OBE-driven ELT pedagogy using Gramsci’s hegemony as a theoretical framework. We aimed to understand how OBE-based ELT tends to transform teachers’ subjectivities into neoliberal ‘selves’, the way it impacts pedagogy and learning of the English language, and how these subjectivities are resisted. It appears that OBE-based ELT circulates market logics in the ELT pedagogy and learning by viewing English language as a skill/commodity. Student learning and teachers’ pedagogical performance indicators are based on achievement of specific outcomes. Some teachers, however, argue that OBE-led ELT deprives them of their pedagogical experiences, freedom, and conceptualizations appropriate for their pedagogical approach. We therefore advocate de-centering and deconstructing neoliberal logics in pedagogy and suggest pedagogy of becoming, critical/dialogic language pedagogy and translanguaging as possible alternatives.
A qualitative study on perceptions of adolescents’ sexual and reproductive health education in Yogyakarta, Indonesia
Authors: Sikoki Bondan , Larastiti Ciptaningrat , Suriastini Ni Wayan , Pujiastuti Setyo
Published: October 2024

Introduction

Sexual and reproductive health (SRH) education in Yogyakarta, Indonesia, is contentious due to societal and religious taboos in the Javanese Muslim community and being misunderstood as a potential catalyst for the premarital sex of unmarried adolescents. The existing practice of SRH education cannot guarantee reliable information about adolescent sexuality. The research aims to understand the intergenerational perception of SRH education conducted at high schools, which has not been comprehensively researched. This qualitative study was conducted in 2016 to explore the perspectives of adults and adolescents regarding school-based SRH education. Focus group discussions and individual interviews were used for data collection, while data analysis was conducted using a feminist perspective.

Content

The study identified gaps in the delivery of SRH education among Javanese Muslim, Indonesia. SRH education had not adequately addressed how adults and adolescents perceived sexuality as taboo due to moral panic about premarital sex and societal expectations placed on girls to maintain their virginity. Peer counsellors, responsible for imparting SRH information and facilitating communication with adolescents, reproduced adult moral values toward their peers, leading to a reluctance among adolescents to share their issues. Consequently, SRH education failed to reach those experiencing unwanted pregnancy or a toxic intimate relationship.

Summary and Outlook

The results of the study indicate the need to challenge intergenerational perceptions regarding sexuality and gender expectations to promote a positive gender perspective within SRH education in Indonesia.
Reproductive physiology of Indian pangolin (Manis crassicaudata) in Pothwar Plateau, Pakistan
Authors: Mahmood Tariq , Bibi Asma , Shamas Shazia , Andleeb Shaista , Akrim Faraz , Khan Bushra Nisar , Qureshi Irfan Zia , Nadeem Muhammad Sajid , Kayani Amjad Rashid , Mushtaq Muhammad , Irshad Nausheen , Noreen Shumaila
Published: October 2024

The Indian pangolin (Manis crassicaudata) is an “endangered” mammal species that is restricted to four range countries of Asia. The ecology and breeding behavior of Indian pangolins is poorly understood due to a lack of scientific data. Due to heavy poaching and illegal killing, the species population has declined drastically in the last decade. Considering the fact that Indian pangolin has low reproductive output, it needs special conservation measures and authentic information about its breeding ecology. We estimated concentrations of three reproductive hormones from scats using ELISA kits in male and female pangolins inhabiting the Pothwar Plateau, Pakistan, to confirm its breeding pattern in its range. Testosterone levels were found elevated from May (0.59 ng/ml) until October (1.28 ng/ml). Oestradiol levels were raised from May (0.59 pg/ml) until December (2.64 pg/ml). Progesterone concentrations were relatively low from January until March but increased from April (4.85 pg/ml) through December (14.0 pg/ml) with highest concentrations (20.13 pg/ml) in September and October. Mean hormone (testosterone, oestradiol and progesterone) concentrations were elevated in winter compared to summer (p < 0.001). The current study is the first one to quantify hormonal levels in this species, and our findings establish the breeding pattern of Indian pangolin.
Protocolo. Cuarta sesión: Políticas y enfoques territoriales en la sociedad colombiana. Conferencistas: Luis Esteban Vallejo y Yuri Elizabeth Quintero
Authors: Ortega Chacón Orlando
Published: October 2024

Las universidades de la Orinoquía se han convertido progresivamente en una plataforma de desarrollo de la región. Sin embargo, es necesario continuar fortaleciendo las redes académicas que permitan el acceso a una “educación inclusiva y equitativa de calidad [que promueva] oportunidades de aprendizaje permanente para todos en América Latina y el Caribe”[1], éstas constituyen aportes para la comprensión de los problemas del territorio y sus oportunidades. Para tales efectos se busca la consolidación de la red de humanidades de la Orinoquía en la modalidad de Coloquio permanente de ciencias sociales y humanas como respuesta a la necesidad de la región y de la agenda 2030. El Coloquio Permanente de Ciencias Sociales y Humanas es un evento organizado por el Departamento de Humanidades y Formación Integral de la Universidad Santo Tomás seccional Villavicencio con el liderazgo del Grupo de investigación Humanidades digitales, formación y construcción de paz territorial (ÁBA). La presente versión es realizada en alianza con la Universidad de San Buenaventura Bogotá. Un evento dirigido a investigadores, docentes y toda la comunidad académica Nacional e internacional que busca lograr el intercambio de conocimiento y experiencias útiles a los temas propios de las Ciencias Sociales y Humanas, los proyectos de investigación y sus diferentes modalidades.
Use of [18F]FDG/PET to access the rosmarinic acid anti-inflammatory effect in a mouse sponge implant model
Authors: Gomes de Almeida Schirmer Brígida , Conceição Duarte Dornelas Isabela , De Avelar Ferreira Letícia , Reis Marques João Vitor , Duarte de Souza Mariana , Barcelos de Miranda Marina , Ribeiro Castro Pollyana , Michel Pereira Jousie , Da Silva Barcelos Luciola , Malamut Carlos
Published: October 2024

Positron emission tomography (PET) is one of the most sensitive and effective imaging techniques for detecting very low concentrations of specific radiotracers. It is suitable for analyzing biochemical, metabolic, physiological and functional information at the molecular level in vivo and non-invasively. PET using 2-deoxy-2[18F]-fluoro-D-glucose ([18F]FDG) can be used to identify sites of inflammation and other pathologies and to monitor the efficacy of treatment. This technique can be used to study the effect of rosmarinic acid (RA) in various preclinical models. RA is a natural compound with promising antioxidant and anti-inflammatory effects. Therefore, the aim of this study is to investigate the anti-inflammatory potential of RA and the efficacy of PET/[18F]FDG in localizing inflammation and assessing response to treatment. A sponge implant model in mice was used for this purpose. All experiments were performed with male BALB/c mice aged 6 to 9 weeks and weighing 18 to 22 g, with 5 animals per group (10 animals in total throughout the study). Methods: The mice were implanted with sponge-like polyurethane discs to induce local inflammation. The animals were divided into two experimental groups: those treated with a vehicle and those treated with RA. PET scans with [18F]FDG were performed to evaluate the inflammatory process. Results: The results obtained with [18F]FDG showed a decrease in inflammatory cell infiltrates in the sponge after treatment with RA. Conclusion: The use of [18F]FDG demonstrated its efficacy in quantitatively evaluating the inflammatory process in the mouse subcutaneous sponge model as well as the anti-inflammatory effect of RA.
Molecular Insights into the Potential Anticancer Property of a Diimine-Diazo Molecule: A Molecular Docking and Molecular Dynamics Simulations Perspective
Authors: Dilek Ömer , Dede Bülent , Karabacak Atay Çiğdem , Tilki Tahir
Published: October 2024

Cancer is a disease in which cells grow abnormally and uncontrollably and destroy body tissue, and it is one of the most important threats to human health. In this study, the interaction of a molecule containing imine and azo groups (DIDA) with tumor growth-related VEGFR2 (PDB ID: 2XIR) and EGFR (PDB ID: 1M17) proteins was investigated by molecular docking and molecular dynamics simulation methods. The molecular docking study revealed that the best binding occurred between DIDA-2XIR with a binding energy of -12.4 kcal/mol. Molecular dynamics simulation was used to verify the stability of the DIDA-2XIR complex. RMSD, RMSF, SASA, Rg parameters and number of hydrogen bonds obtained during molecular dynamics simulations showed that the DIDA-2XIR complex was stable at the molecular level. Our findings have made an important contribution to the understanding of the mechanism of interaction of the DIDA with VEGFR2 and support its availability as a potential VEGFR2 inhibitor.
„Polska” i mesjanizm w pismach s. Heleny Rafaeli Majewskiej CSA, wileńskiej apostołki Bożego miłosierdzia
Authors:   Uniwersytet Mikołaja Kopernika w Toruniu, Damazyn Michał
Published: October 2024

Helena Rafaela Majewska CSA (1902–1967) infiltrated the habitless congregation of the Sisters of Angels. Mystic; propagator of God’s mercy; penitent and collaborator of Fr. Michał Sopoćko – Vilnius confessor of Sister Faustyna Kowalska; continuator of her message. Majewska left a spiritual Diary from the years 1941–1943, in which a patriotic and messianic theme appears, the author will appear as an element of the message of mercy and the perspective of the fate of Poland revealed to her by God. The texts constitute their important sources, from which come the records of the Way of the Cross of the Polish Nation, where the mystic assigned the events of the subsequent World War II to the emergency station. The analysis of Majewska’s spiritual records is valuable both from the point of view of theological and historical sciences. In the first case, they reveal the obligation of patriotism in the formation and experience of religion in the early 20th century and during the Second Mandatory War. In the second one – revealing the elements of Polish messianism and allowing the use of interpretation of historical events at the time they occurred.
Zarządzanie bezpieczeństwem Muzeum Narodowego w Krakowie
Authors:   Uniwersytet Ekonomiczny w Krakowie, Jurek Krzysztof
Published: October 2024

When I think about a museum, many different threads come to mind, including memories from both my childhood and adult life. In the past, school trips were often organized to museums, where for the first time for many it was an opportunity to encounter a large amount of art and works gathered in one place. Although as a child it is difficult to evaluate and develop deeper reflections on the work you are learning, contact with exhibits from an early age teaches you proper respect for learning about them, emphasizing how important they are for everyone. The topic of museums is also often reflected in film art, where these places often become targets for thieves who plan in a sophisticated way over a long period of time to obtain a given exhibit. Often silently, bypassing all security measures, so that the museum only learns about this fact when the morning shift comes to work, and the works are already far outside the museum, and this security issue is the subject of this work.
Two approaches to the semantic decomposition of change of state verbs, how they differ, and why it matters
Authors: McNally Louise
Published: October 2024

In this paper, I contrast two broad decompositional approaches to verb semantics. One, especially associated with David Dowty, involves translating verbs using a set of precisely interpreted primitive predicates such as CAUSE and BECOME, in order to facilitate semantic generalizations such as patterns of entailment between sentences. Another, with multiple origins in both temporal semantics and theories of the syntax/semantics interface (including, notably, work by Pustejovsky and Piñón), involves developing a theory of the internal part structure of the eventualities that verbs and other expressions describe; I refer to this approach, following Pianesi and Varzi, as mereotopological. These two approaches to decomposition are not, strictly speaking, incompatible, and they have sometimes been combined; however, perhaps surprisingly, comparison of them has been unsystematic. I address this gap by describing more systematically how the approaches differ from each other, illustrating with differences in the insights they offer into specific aspects of the semantics of simple change of state verbs and unselected object resultatives. I especially aim to promote interest in the development of more sophisticated, cross-linguistically applicable theories of so-calledevent structure through appeal to a wider range of notions from mereotopology.
Numerical method for restoring the initial condition for the wave equation
Authors:   Azerbaijan State Oil and Industry University, Gamzaev Khanlar M.
Published: October 2024

The inverse problem of restoring the initial condition for the time derivative for the one-dimensional wave equation is considered. As an additional condition, the solution of the wave equation at a finite time is given. First, the discretization of the derivative with respect to the spatial variable is carried out and the initial problem is reduced to a differential-difference problem with respect to functions depending on the time variable. To solve the resulting differential-difference problem, a special representation is proposed, with the help of which the problem splits into two independent differentialdifference problems. As a result, an explicit formula is obtained for determining the approximate value of the desired function for each discrete value of a spatial variable. The finite difference method is used for the numerical solution of the obtained differentialdifference problems. The presented results of numerical experiments conducted for model problems demonstrate the effectiveness of the proposed computational algorithm.
Saz kedisi (Felis chaus S.) habitat uygunluk modellemesi ve haritalaması
Authors: Acarer Ahmet
Published: October 2024

Yaban hayatı yönetim planlarının oluşturulması için örtü, besin, su ve mekân gibi habitat faktörleri öncelik oluşturmaktadır. Dolayısıyla nesli tehlike altına girme potansiyeline sahip yaban hayvan türlerinin habitat tercihinde rol oynayan ana faktörlerin ortaya koyulması, koruma ve yönetim planlarına altlık oluşturmaktadır. Bu nedenle Türkiye’deki nesli asgari endişe altındaki (LC) Saz kedisinin (Felis chaus Schreber, 1777) habitat uygunluk modellemesi ve haritalaması amaçlanmıştır. Bu amaçla Saz kedisi türüne ait 81 var verisi yaban hayatı habitat uygunluk modellemelerinde sıkça tercih edilen Maksimum Entropi (MaxEnt) yöntemiyle analiz edilmiştir. Model sonuçlarına göre modelin eğitim veri seti ROC:0.976, test veri seti ROC:0.969 olmasıyla “oldukça iyi” model kategorisinde yer almaktadır. Modele katkı sağlayan değişkenlerin yıllık sıcaklık aralığı, yükselti, arazi yüzey şekil indeksi, engebelilik, yıllık ortalama sıcaklık ve yıllık yağış miktarı olduğu tespit edilmiştir. Modele katkı sağlayan değişken değer sonuçlarına göre Saz kedisinin sayısal ve model tabanlı habitat uygunluk haritalaması ortaya koyulmuştur. Haritalama sonuçları Türkiye genelinde Saz kedisinin göl ve delta olan bölgelerde yoğunlaştığını ortaya koymuştur. Sonuç olarak; yapılan bu haritalama Saz kedisi için yapılacak planlama ve koruma çalışmalarına katkı sağlayacak niteliktedir.
Susam bitkisinin çimlenme ve fide gelişimi üzerine kurşun klorür’ün (PbCl2) etkisi
Authors: Gedik Osman , Kıllı Fatih , Körük Nurdan Gül
Published: October 2024

Susam (Sesamum indicum L.), endüstri bitkileri arasında çok önemli bir yere sahiptir. Bu çalışmada susam tohumlarına, çevre kirleticilerden biri olan kurşun (PbCl2) ağır metal vericisinin farklı dozları uygulanarak çimlenme ve fide gelişim özellikleri incelenmiştir. İki farklı susam çeşidi (Kepsut-99 ve Hatipoğlu) ve 0 mg L-1 (Kontrol), 5 mg L-1, 10 mg L-1, 20 mg L-1, 40 mg L-1, 80 mg L-1, 160 mg L-1, 320 mg L-1 olmak üzere 8 farklı PbCl2 dozu uygulanmıştır. Hazırlanan petri kaplarının tabanları çift katlı filtre kâğıdı ile kaplanmış ve her petri kabına kendi dozundan 10 ml konsantrasyon sıvısı eklenmiştir. Her petri kabına 50 adet tohum ekilmiş olup petri kapları parafilm ile kapatılarak inkübatöre yerleştirilmiştir. Daha sonra 24 oC sıcaklıkta 12 saat karanlık ve 12 saat aydınlık olacak şekilde programlanan inkübatöre petri kapları yerleştirilmiştir. Çalışmadaki ölçümler denemenin kurulumundan on dört gün sonra alınmıştır. Buna göre; çimlenme oranı bakımından susam çeşitleri arasında fark görülmezken radikula yaş ve kuru ağırlık, plumula kuru ağırlık ve fide kuru ağırlık dışındaki incelenen tüm özelliklerde Hatipoğlu çeşidi daha yüksek değerlere sahip olmuştur. Dozlar açısından incelendiğinde PbCl2 konsantrasyonlarının artışına bağlı olarak incelenen özelliklerin değerlerinde azalma görülmüştür. Çeşit x doz interaksiyonu bakımından incelenen parametrelerin bakıldığında çeşitlerin PbCl2 dozlarına olan toleransları farklılık göstermiştir.
Türkiye’de orman yangınlarına müdahale sürecinde yaban hayatına yönelik ilk yardım yönetimi hakkında güncel değerlendirme
Authors: Yalçın Sefa , Urker Okan
Published: October 2024

Türkiye'deki orman yangınlarının artışıyla birlikte, yaban hayatının korunması için acil yardım yönetimi giderek daha kritik bir hale gelmektedir. Bu araştırmada, Türkiye'de 2017 ile 2022 yılları arasında gerçekleşen orman yangınları ve bu yangınlar esnasında yaban hayatına yönelik ilk yardım uygulamalarıyla ilgili haberler, raporlar, makaleler ve diğer yazılı kaynaklar literatür taraması yapılarak analiz edilmiştir. Ayrıca, söz konusu dönemde etkin rol alan yaban hayatı veteriner hekimleri, belediyelere bağlı itfaiye personeli ve orman işletme müdürlüklerinin yangına ilk müdahale ekiplerinden uzmanlarla yüz yüze veya çevrimiçi görüşmeler gerçekleştirilerek bilgi toplanmıştır. Araştırmanın sonucunda, Doğa Koruma Milli Parklar Genel Müdürlüğü ile Orman Genel Müdürlüğü’nün ana koordinasyonunda Türk Veteriner Hekimler Birliği, Belediyeler ve ilgili STK’lar ile farklı paydaşlara yönelik koordineli bir şekilde düzenli teorik ve pratik eğitimler verildiği takdirde yangından zarar görmüş olan canlıların hayatta kalma şansının yükseleceği tespit edilmiştir. Bu araştırma, orman yangınlarının ormana bağımlı yaşamı sürdüren yaban hayatı üzerindeki olumsuz etkilerini en aza indirgemek için daha etkili ilk yardım yönetim stratejilerinin kurulma aşamalarına işaret ederken, bu sürecin doğru biçimde uygulanmasının önemini de vurgulamaktadır.
Makine öğrenmesi yöntemleri ile hisse senedi fiyat tahmini: kâğıt firması örneği
Authors: Bardak Selahattin , Ersen Nadir , Polat Kinyas , Akyüz Kadri Cemil
Published: October 2024

Bir finansal formül kullanarak hisse senedi fiyatlarını tahmin etmek zordur. Hisse senetleri fiyatları, siyasi gelişmeler, küresel ekonomi, beklenmedik olaylar, piyasa anormallikleri ve ilgili şirketlerin özellikleri gibi çok sayıda faktörden etkilenir. Hisse senedi fiyatlarına ilişkin daha doğru tahminler yapmak için bilgisayar biliminin gelişmesiyle birlikte birçok bilgisayar bilimi yöntemi kullanılmaktadır. Bu çalışmada, Kartonsan şirketinin hisse senedi fiyatını tahmin etmek için doğrusal regresyon (LR) algoritmaları, rastgele orman (RF), gradyan güçlendirme makinesi (GBM) ve yapay sinir ağları (YSA) gibi makine öğrenmesi teknikleri kullanılmıştır. Daha sonra kullanılan algoritmaların sonuçları karşılaştırılmıştır. Hisse senedi fiyatı tahmini için ilk olarak BIST (Borsa İstanbul)’te işlem gören Kartonsan firmasının 2011-2022 yılları arasındaki üçer aylık finansal çizelgeler kullanılarak firmaya ait finansal oran hesaplanmıştır ve bu oranlar girdi olarak kullanılmıştır. Çıktı olarak kullanılan firmanın hisse senedi fiyatlarının ise üçer aylık ortalamaları alınmıştır. GBM ve RF algoritmaları başarılı tahmin sonuçlarına sahip olmasına rağmen GBM algoritması en başarılı sonucu vermiştir. RF algoritmasının ise LR ve YSA’ya göre daha iyi performans gösterdiği bulunmuştur. YSA’nın hisse senedi fiyat tahmininde en kötü performansa sahip teknik olduğu belirlenmiştir.
Evaluation of computer aided design (CAD) systems and their usage efficiency in Türkiye furniture industry
Authors: Erdinler Emine Seda , Koç K. Hüseyin
Published: October 2024

Computer-aided design (CAD), briefly refers to the utilization of computers to ensure quality and efficiency in design. CAD systems developed in the 1960s in the United States and their consequent application in all developed countries was discussed, focusing on making these systems more effective in the industry and evaluating their implementation conditions in the Turkish furniture sector. Accordingly, the objective of this current research is to summarize the effectiveness of CAD systems in the 2000s while evaluating current applications and their future impacts. In the 2000s, CAD systems required significant labor, hardware, and software support. In the current globalized world, CAD systems have become even more user-friendly with the support of artificial intelligence (AI), alongside more effective applications. The research employed face-to-face survey methods, focusing on large-scale furniture enterprises in the Marmara region. The results were evaluated using SPSS software and reliability tests. In the 2000s, approximately 25% of Turkish furniture enterprises expected CAD systems to shorten the design process, improve product quality, and enhance demand and order fulfilment times. Evaluations of today's enterprises indicate that these expectations remain. Many furniture enterprises in Türkiye utilize integrated software with CAD systems in handling orders. Approximately 46% of Turkish furniture enterprises report efficient use of these programs, while the remaining 54% cite a lack of trained personnel as the reason for inefficient use. CAD applications have contributed to the development of Turkish furniture enterprises. With CAD applications, the order process has decreased by 57 %, and production has increased by 34%. This research aims to provide insights into the current state and future potential of CAD systems in the sector by examining the developments and transformations over the past two decades.
Türkiye Periploca (Periplocoideae: Apocynaceae) taksonlarının morfolojik ve korolojik özellikleri
Authors: Güven Seher , Sarıkaya Eyüp
Published: October 2024

Periploca cinsi Türkiye’de P. gracilis ve P. graeca taksonları ile temsil edilmektedir. Mevcut araştırmada bu iki taksonun morfolojik özelliklerinin yeniden değerlendirilmesi ve korolojik özelliklerinin güncellenmesi amaçlanmıştır. Morfolojik incelemeler, türlerin doğal yayılış alanlarından yeni toplanan ve ulusal/uluslararası herbaryumlarda muhafaza edilen örnekler üzerinden gerçekleştirilmiştir. Ayrıca, incelenen taksonların detaylı morfolojik fotoğraflarını içeren genişletilmiş betimleri ve Türkiye’deki güncel yayılış haritaları oluşturulmuştur. Sarılıcı çalı formunda olan her iki Periploca taksonundan, P. gracilis ince yapılı gövdesi, küçük yaprakları (10–50 mm), beyaz ya da yeşilimsi sarı ve tüysüz korollası, ipliksi ve uçta iki parçalı korona segmentleri, akut ya da yatay olarak ayrılmış uçları serbest ve 50–115 mm uzunluktaki folikülleri ile karakterize edilirken, P. graeca nispeten daha gelişmiş gövde, yaprak (30–155 mm) ve meyvelere (60–170 mm), mor menekşe renginde ve üst yüzeyi kenarlar boyunca ince uzun yumuşak tüylü (villous) korollaya, ipliksi ve parçalanmamış korona segmentlerine, akut olarak ayrılmış ve uçtan hafifçe birleşmiş foliküllere sahiptir. Türkiye’de P. gracilis taksonunun 7, P. graeca taksonunun ise 91 lokalitede yayılış gösterdiği belirlenmiştir. Bu çalışma ile Türkiye’de yayılış gösteren Periploca taksonlarının morfolojik betimlerine önemli bir katkı sağlanmış ve ülkedeki dağılımları güncellenmiştir.
Orman Fakültesi öğrencilerinin iş sağlığı ve güvenliği konusunda farkındalıklarının analizi (Düzce Üniversitesi)
Authors: Çil Muhammet , Gedik Tarık
Published: October 2024

Bu çalışmada, Düzce Üniversitesi Orman Fakültesi bölümlerinde eğitim gören lisans öğrencilerinin iş sağlığı ve güvenliği (İSG) konularındaki farkındalıklarının belirlenmesi amaçlanmıştır. Bu kapsamda Orman Fakültesi bünyesinde dört farklı bölümde eğitim gören 661 lisans öğrencisi, çalışmanın evrenini oluşturmuştur. %95 güven düzeyi ve %10 hata payına göre 88 lisans öğrencisine ulaşılabilmiştir. Çalışma kapsamında geliştirilen anket formu, katılımcı öğrencilere yüz yüze yöntemle uygulanmıştır. Çalışmada, cinsiyet, yaş, bölüm, barınma şekli ve ailenin gelir durumu gibi demografik faktörler ile katılımcı öğrencilerin İSG konularındaki farkındalıkları analiz edilmiştir. Çalışma sonucunda, katılımcı öğrencilerin eğitim hayatları boyunca acil durum eylem planı ve risk analizi gibi eğitimleri alması gerektikleri ve aldıkları ya da alacakları İSG eğitimlerinin iş hayatında onlara katkılar sağlayacağı belirlenmiştir.
In the Shadow of Crisis: Social and Political Transformations of Covid-19
Authors: Üstün Kutay
Published: October 2024

The Covid-19 pandemic has impacted our country in many ways, much like it has affected the rest of the world. This study focuses on examining the effects of the pandemic on individuals. It delves into the experiences of participants during the outbreak, the societal and political implications of implemented policies, and the policies aimed at curbing the spread of Covid-19. The study conducted through a survey involving 375 students from Ardahan University reveals the negative effects of the pandemic on individuals. Situations of distancing, avoidance, and maintaining social distance during the outbreak have triggered feelings of helplessness, fear, and anxiety among individuals. Additionally, policy measures such as social isolation have led to significant changes in individuals' lifestyles. Factors such as remote work, online education, temporary closure of businesses, and the inability to participate in social activities have had negative effects on individuals. The Covid-19 pandemic has created an atmosphere of uncertainty and fear, undermining the trust among people, and profoundly affecting societal order. As the perceived threat of the pandemic diminishes, support for implemented policies has also decreased. This study contributes to our comprehensive understanding of the societal and political transformations brought about by Covid-19.
Hydrogen therapy from the initiation to its practical applications
Authors: Ohta Sh.
Published: October 2024

Molecular hydrogen (H2) has emerged as a therapeutic and prophylactic agent devoid of adverse effects. H2 demonstrates multifaceted functionality across diverse cell types and organs, attributable to its interaction with oxidized hemes as a fundamental molecular mechanism. Given the abundance of various heme types both intracellularly and extracellularly, the broad-ranging effects of H2 are comprehensible. Subsequent Pathways are mediated by end-or modified- products of lipid peroxide followed by free radical chain reactions. Notably, H2 confers benefits not only to patients afflicted with diseases but also to individuals seeking to enhance health and wellness. The mission of hydrogen medicine encompasses addressing unresolved medical challenges, including cerebral infarction, post-cardiac arrest syndrome, advanced cancer, metabolic syndrome, and dementia. Transitioning from animal experiments to clinical studies is imperative to confront these formidable diseases effectively.
Mitochondrial dysfunction in patients with respiratory diseases
Authors: Mishlanov V. Ju. , Chuchalin A. G. , Chereshnev V. A.
Published: October 2024

The aim of this scientific literature review was to find new solutions to urgent problems of treating respiratory diseases and reducing the associated temporary loss of ability to work and disability. The article presents the results of the analysis of 62 scientific papers published over 23 years (2001 – 2023) on mitochondrial dysfunction (MD), new methods of its diagnosis, and ways of its correction in respiratory diseases. Disorder of the energy function of mitochondria has been identified as an urgent scientific problem of respiratory medicine. It is noted that new methods of pathogenetic therapy for common and currently difficult-to-treat diseases are being developed to solve this problem. The key section of the review is devoted to the results of studies of mitochondrial dysfunction in patients with asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and pulmonary hypertension.

Conclusion. The article assesses MD diagnostic methods that are potentially applicable in real clinical practice. The results of studying the electric potential of the inner mitochondrial membrane, accumulation of active forms of oxygen, production of adenosine triphosphate in blood cells, alveocytes and epithelium of the respiratory tract, as well as bronchial smooth muscle cells, endothelium and vascular smooth muscle cells in the pulmonary artery system, determination of mitochondrial DNA in biological environments are compared. Proposed methods for the correction of MD syndrome in the clinical picture of respiratory diseases are briefly covered.