bluuebunny/crossref_metadata_2025 huggingface dataset:
Patentometric Profile of Social Water
Authors: Carvalho Ramon Santos , Mendonça Valéria Melo , Silva Gilton José Ferreira da , Santos Mário Jorge Campos dos
Published: July 2020

There are regions of the planet that are affected by climatological conditions that cause water scarcity. Thus, innovative techniques have emerged with the purpose of mitigating the reflexes caused by the natural factor: drought. These innovations arise with the objective of capturing, storing and carrying out rainwater treatment for the population. These, called social water technologies, comprise products, techniques or replicable methodologies that are developed specifically to solve the problem of water shortages. The present work aims to analyze the profile of innovations generated by social water technologies through the LATIPAT, INPI and WIPO bases. To search for patents, keywords that were relevant to the research were used and combined with Boolean operators. 907 patents were identified, the largest concentration of deposits in China, justified by the fact that the country adopts development policies that invest in R&D, differentiating itself from other countries. Among the patents analyzed there is a higher concentration of deposits related to the area of ​​human needs and water treatment.
effectiveness of the Internal Control System as a regulatory element in Public Pension Expenses for Accountabilty
Authors: Costa Castro José , Nogueira Dr. Ricardo Jorge da Cunha Costa
Published: July 2020

This article used theorists to reinforce data on the effectiveness of the Internal Control System as an instrument that regulates public pension expenditure for Accountabilty. This topic allows the understanding of the importance of internal control as a practice that helps in the quality and results of an organization, because Accountability represents the obligation of accountability for the performance of a work from the responsibility of a delegated authority. How much and how the Internal Control System can assist the manager in decisions? The general objective is to analyze the effectiveness of the internal control system in order to serve pension institutions more effectively. The methodology was bibliographic, exploring magazines and websites, besides the Brazilian legislation; the data collection was carried out at the Public Servants Welfare Institute of the State of Rondônia (IPERON). It was possible to conclude that it is necessary for IPERON's Internal Control Sector to develop its activities according to its mission and vision so that qualitative results have priorities.
Social Media Marketing Communication
Authors: Tardin Matheus , Soncini Pelissari Anderson , Dazzi Braga Luiza
Published: July 2020

The objective of this work is to evaluate the effects of firm generated content (FGC) and user generated content (UGC) on brand equity (BE) and on the consumer's purchase intention. To achieve it, the research methodological approach was quantitative, cross-section survey type. Data collection was carried out by an online survey, and 322 valid responses were obtained. The proposed model was analyzed using the Structural Equation Modeling method (PLS-SEM). The results show that both the firm generated content and the user generated content influence brand equity. The content generated by the company, however, has a greater effect and has greater power to explain brand equity than the content generated by the users. On the other hand, the direct effects of FGC and UGC on the intention to buy are not significant when the effect of brand equity is considered. Therefore, this research contributes to the theoretical framework of marketing, specifically in the areas of relationship and digital marketing, by being one of the first to assess the joint effects of the content generated by the brand and by the consumer on brand equity and purchase intention.
ANALYSIS OF STRATEGIC COST MANAGEMENT ASSISTING IN DECISION MAKING
Authors: Barroso Yuri , Souza Junior Armando
Published: July 2020

This work presents a study on the cost formation process of a third-party service provider from the Federal Public Administration to draw a parallel with the strategic cost management using the absorption and variable costing methods. As a methodology, a qualitative-quantitative research strategy, of an applied nature, was used, through a case study in a company that provides cleaning, conservation, and sanitation services. Data on 13 types of inputs (the highest values) were analyzed over six months. The values were highlighted referring to the input data of the Bidding Notice that led to the contracting of the service provider company, the inputs consumed by the client, and the inputs purchased by the company. The results of the study indicate that the company bought twice as much (119%) than the amount foreseen in the notice on the analyzed period. Using the precepts of Strategic Cost Management, in parallel with the absorption and variable costing methods, it can be observed that in terms of making managerial decisions, the second (variable costing) forwards more critical information to the manager than the first ( absorption costing), resulting from the concern of complying with Brazilian tax legislation, without considering the inherent tax costs (not only) in the operational structure of the type of service object in this study.
Evaluation of the potential toxicity of haloperidol, clozapine and a new putative antipsychotic molecule, PT-31, in an alternative toxicity model, C. elegans
Authors: Bigolin Cassiana , Sant’Anna Oliveira Talitha Stella , Cé da Silva Laura , Ayres Tainara , Machado Menezes Júlia , Da Rocha Pitta Ivan , Feiffer Charão Mariele , Heemann Betti Andresa
Published: July 2020

Schizophrenia is a disabling mental illness that affects approximately 1% of the world population. The treatment of this disorder is based on two generations of substances, typical antipsychotics, such as haloperidol, and atypical antipsychotics, such as clozapine, which can cause severe adverse effects. Therefore, the development of novel molecules that are safe and efficacious to treat the disease is crucial. PT-31 is a putative α2-adrenoceptor agonist effective against schizophrenia positive and cognitive symptoms in mice. C. elegans is an alternative model that has been successfully used to investigate the toxicity of a variety of substances. The present study aimed to evaluate the potential toxicity of the new molecule PT-31 and the antipsychotics haloperidol and clozapine in C. elegans. The evaluation was carried out based on toxicity endpoint tests, survival, developmental and behavioral assays. The antipsychotics haloperidol and clozapine decreased nematode survival by 30 and 40%, respectively, exposing the potential toxicity of these substances whereas PT-31 was safer based on this parameter. Similar results were obtained in the nematode developmental assay: haloperidol and clozapine significantly reduced nematode body length and area, whereas PT-31 preserved the normal development of the nematodes. The behavioral assessment was based on the frequency of body bends; none of the antipsychotics affected the locomotion rate of the nematodes, and PT-31 also did not compromise this parameter, demonstrating the safety of this new compound and reinforcing the recognized toxicity of antipsychotics.
Active Teaching-Learning Methodologies in an Undergraduate Course of Medicine with a Traditional Curriculum
Authors: Araújo Raul Angeli , Zanatta João Marcos de Menezes , André Julio Cesar , Lima Daniella Ladeia de , Brienze Sérgio Luís Aparecido , Santos Júnior Randolfo dos , Santos Loiane Letícia dos , Lima Alba Regina de Abreu
Published: July 2020

The current technological configuration added to the present social demands in health make it necessary to review the teaching-learning methodologies applied during the graduation of the medical professional. Those necessities are addressed by the National Curricular Guidelines, which preconize the adoption of methodologies that stimulate the student's autonomy and put the faculty in compliance with the current situation. To obtain a panorama about the medical students’ perception in a college of a inland city of the São Paulo state in relation to the Active Teaching-LearningMethodologies (ATLM) this cross-sectional, descriptive-exploratory, quantitative analysis was carried out where the participants were students of the Medical School of São José do Rio Preto - FAMERP in 2017. Through a mixed questionnaire, that is, with open and closed questions, data were collected necessary to reach the objective. A total of 364 students participated, of whom 70.9% agreed they would like to use ATLM more often. Regarding the role of the student: 80.7% agreed that ATLM stimulate the study; 73.3% agreed that group activities support learning; 44.2% disagreed that students are not prepared for ATLM due to lack of maturity and 51.1% agreed that they are unprepared to use ATLM for being accustomed to traditional teaching methods. Data show that, even though they do not attend classes with ATLM frequently, the students can be very interested in execute them. Emphasis is given to his intense perception of learning in these moments. The student profile that compares with the ATLM is the one that knows them, that is, those who have had contact with such methodologies want to use them more frequently. In addition, students consider that the teachers’ role should be that of a learning facilitator, who guides the studies so that the academic goals are achieved.
Advances in HealthCare teaching
Authors: Pinheiro Islla Ribeiro , Gondim Victor José Timbó , Martinez Maria Elisa Marciano , Reis Marcello Carvalho dos , Alexandria Auzuir Ripardo de
Published: July 2020

The objective in this article, the realization of a patent mapping on medical education, especially using simulators, since we know that in the teaching of medicine, the development of technical and motor skills in practice is essential, and historically, this training happens with the use of corpses, small animals and later monitoring procedures. With all the advent of technological innovation, financial, cultural and social changes demanded the emergence of new teaching technologies, and through this study, one of the utilities of the technological mapping of the activity can be confirmed through patent documents, which is to obtain the technological evolution of a given subject, in this case: use of models, including simulators in medical education. The temporal evolution of patent documents referring to medical education peaked from 2009 to 2018, and above all, it can be concluded that the latest technologies are models of simulators and there are indications from the United States in exporting this technology to Brazil. recent. From this mapping, it is possible to subsidize technological innovation strategies and assist in the promotion of policies and legislation aimed at stimulating national entrepreneurship and the generation of business opportunities.
ADHESIVE PROPERTIES OF BACTERIA UNDER THE INFLUENCE OF BIFIDOBACTERIUM BIFIDUM 1 AND LACTOBACILLUS REUTERI DSM 17938I CELL-FREE EXTRACTS
Authors: Knysh O.V. , Kolpak S.A. , Pogorila M.S. , Babych Ye.M.
Published: July 2020

Increasing in the adhesive potential of probiotic bacteria on the one hand and weakening the adhesive ability of the pathobionts on the other is a pathogenetically based approach in the fight against intestinal infectious diseases and intestinal dysbiosis. At present postbiotic products are considered as one of the most promising means of influencing the intestinal microbiota. The aim of the work was to study the effect of cell-free extracts containing derivatives of Bifidobacterium bifidum 1 and Lactobacillus reuteri DSM 17938 on the adhesive properties of probiotic (L. reuteri DSM 17938 and B. bifidum 1) and opportunistic bacteria (Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922). Four cell-free extracts were investigated: L – obtained from the L. reuteri disintegrate; ML – obtained from the L. reuteri culture, cultivated in its own disintegrate; B – obtained from the B. bifidum disintegrate; MB – obtained from the B. bifidum culture, cultivated in its own disintegrate. The effect of cell-free extracts on the adhesive properties of microorganisms was studied by using Brilis method. ML, MB, and B extracts were found to be able to significantly increase the adhesive potential of B. bifidum and L. reuteri. Under their influence adhesion index calculated for bifidobacteria increased by 41.1 % (ML), 41.5 % (MB) and 50.6 % (B), and the microorganism adhesion index calculated for lactobacilli increased by 30.77 % (ML), 44.45 % (MB) and 44.97 % (B). Both studied probiotic bacteria moved up from the category of «moderately adhesive» into the category of «strongly adhesive» with microorganism adhesion index > 4.0. Lactobacilli also became «strongly adhesive» under the influence of L extract, while microorganism adhesion index increased by 37.9 %. Among the studied extracts, only L extract caused a significant increase in the adhesion index of the S. aureus test culture. The other extracts caused minor changes in the adhesive potential of the test cultures. Under their influence, there was a tendency to increase or decrease the adhesive ability of bacteria. Under the influence of MB extract, the S. aureus test culture passed from the «strongly adhesive» category to the «moderately adhesive» category, and the E. coli test culture transferred from the «moderately adhesive» category to the «weakly adhesive» category. The data obtained are of great importance when developing new metabiotics based on the B. bifidum 1 and L reuteri DSM 17938 probiotic strains derivatives.
CHANGES IN EATING BEHAVIOUR OF YOUNG PEOPLE WITH DIFFERENT BODY WEIGHT
Authors: Kolinko L.M.
Published: July 2020

Along with the excess food consumption and the sedentary lifestyle, dysregulation of eating behaviour contributes much to the development of overweight and obesity and often becomes a component of pathogenesis in the number of diseases and conditions. The purpose of this study was to determine the characteristics of eating behaviour in young people with normal body weight, overweight and with obesity class I. The study included 96 individuals aged 18–25. There were evaluated anthropometric parameters and the body fat percentage by the circumference measuring. Based on the body mass index, all subjects were divided into 3 sex-balanced groups of 32 individuals in each: a group with body mass index ranging from 18,5 to 24,9 kg/m2, a group with increased body weight (body mass index from 25,00 to 29,99 kg/m2), and a group with obese class I individuals (body mass index from 30,00 to 34,99 kg/m2). A Dutch Eating behaviour Questionnaire and a 3-factor Stunkard, Three-factor Eating questionnaire - 18 were used to assess eating behaviour. The results were processed statistically. Results. According to the findings obtained by using the Dutch Eating behaviour Questionnaire, the restrictive type of eating disorders was more prevalent in male individuals with obesity class I and in female individuals of all groups. The external type was more pronounced in the men of all groups studied. According to the findings of Three-factor Eating questionnaire - 18, the cognitive restriction type was found as a dominant type of eating behavioural disorders. Between the indicators of eating disorder types according to the Dutch Eating behaviour Questionnaire and Three-factor Eating questionnaire - 18 and anthropometric indicators there has been found mainly positive correlation of high and medium strength in the individuals with normal weight, while the negative correlation of high and medium strength has been detected in the overweight and obese individuals of both sexes. The results obtained point out the need in individualized approach in modifications of the dietary pattern in young people, the importance of mandatory psychological correction, and their combining with other components of weight loss strategies.
S-ADEMETHIONINE EFFECT ON THE ACTIVITY OF FREE RADICAL OXIDATION PROCESSES AND ARGININE/CITRULLINE CYCLE WITH DOXORUBICIN-INDUCED LIVER INJURY
Authors: Maslova G.S. , Skrypnyk R.I. , Skrypnyk І.М.
Published: July 2020

Seeking for effective methods for doxorubicin-induced toxicity prevention is of great clinical importance. The aim of the study is to investigate the effect of S-ademethionine on the activity of free radical oxidation and antioxidant protection and arginine / citrulline cycle, and the relationship between the indicators during the modeled doxorubicin-induced liver injury in rats. Materials and methods. The series of study were performed on 30 white non-linear adult rats, 15 (50%) males, 15 (50%) females, weighing 160-220 g. The experimental animals were divided into 3 groups: I group (n=10) included rats (5 males and 5 females), which during 3 days were intraperitoneally administered with doxorubicin of 5 mg/kg/day to achieve cumulative dose of 15 mg/kg and 0.9% sodium chloride solution 1 ml; ІІ group (n=10) included rats (5 males and 5 females), which for 3 days were administered with doxorubicin in dosage similar to that in group I and S-ademethionine intraperitoneally in a dose of 100 mg/kg/day with a total dose of 300 mg/kg; ІІІ group (n=10) included rats (5 males and 5 females), which were injected intraperitoneally for 3 days with 0.9% sodium chloride 1 ml solution by 2 injections. Thiobarbituric acid reactants, arginine, catalase, arginase and ornithine decarboxylase activity were studied in the liver homogenate. Results. The rats of group I in the course of doxorubicin administration demonstrated the growth of the thiobarbituric acid reactants in 2.57 times (p=0.002) in the liver homogenate that was accompanied by 1.7-fold decreased arginase activity compared to the control group III. An inverse correlation was found between the content of thiobarbituric acid reactants and arginase activity in the liver homogenate of group I rats (r=-0.71; p=0.02). Coadministration of S-ademethionine and doxorubicin administration led to 1.4-fold increase in catalase activity in the liver homogenate of rats compared to the control (p=0.009) that reduced the severity of oxidative stress and prevented changes in the arginine/citrulline cycle. Conclusions: S-ademethionine combined with doxorubicin, reduces the activity of free radical oxidation by potentiating the production of antioxidant protective enzymes that prevent impairments in the arginine / citrulline cycle.
ON SOME MORPHOLOGICAL PROGNOSTIC CRITERIA FOR PROSTATE CANCER
Authors: Med V.V. , Babenko V.І. , Filenko B.M.
Published: July 2020

Acinar adenocarcinoma of varying degrees of differentiation is considered the most common histological form of prostate cancer. The major diagnostic criterion to be considered when choosing a method of treatment for prostate cancer is the morphological atypism of the glands, which is reflected in the Gleason grading scale, as well as the degree of expression of immunohistochemical markers, one of which is alpha-methylacyl-CoA racemase. However, the dependence of the expression of p504S on the degree of tumour grading by the Gleason grading system is not fully understood to date. The paper was aimed at establishing a relationship between the degree of differentiation of prostatic adenocarcinoma according to the Gleason grading scale and the degree of expression of the p504s IGC marker. Biopsy material obtained from 37 patients with prostate cancer was examined. According to the Gleason grading scale, the material was divided into three groups: 1-4 scores for the first group, 5-7 scores for the second group and 8-10 scores for the third group. IGC studies on determination of the p504s antigen expression were performed using monoclonal anti-AMACR/P504s. The analysis of the relationship between the degree of differentiation of the prostatic adenocarcinoma according to the Gleason scoring and the degree of expression of p504s IGC marker revealed a clear pattern and demonstrated a strong correlation (r=0,69) between these morphological characteristics of the tumour. The revealed pattern indicates the specificity of this marker in malignant tumour processes in the prostate gland, which is consistent with other studies, and enables to make more accurate differentiation of the tumour staging according to the Gleason grading scale. To a certain extent, this provides a basis for the selection of adequate methods of the treatment and for the improvement of prognostic criteria.
MORPHOLOGY OF GLANDULAR AREA OF HARD PALATE MUCOSA IN INTACT ALBINO RATS
Authors: Khilinich Ye.S. , Davydenko V.Yu.
Published: July 2020

Some reports state that the morphology, histochemistry and innervation of mucous membrane in rats are quite similar to that in humans. Most experimental studies on the impact of certain factors on the human body involve laboratory animals, rats in particular. In our previous experimental studies we used rats to study the effect of acrylic monomer on salivary glands in order to further extrapolate data to the morphological features of minor salivary glands of rats and humans. This study was aimed at investigating morphology of glandular area of the hard palate mucosa of intact albino rats with subsequent extrapolation of the results obtained to human body. The experimental studies were conducted on adult Wistar rats aged 1 to 1.5 years. The light microscopy (slight magnification) of transverse sections of the hard palate mucosa samples of albino rats revealed the mucous membrane and well-developed submucous layer with numerous minor salivary glands within its structure. The findings confirm the similarity between the structure of minor salivary glands of rats and humans that supports the rational choice of experimental animals for subsequent extrapolation of the resulting data.
TREATMENT OF DEGENERATIVE CHANGES IN THE EPITHELIUM OF THE OCULAR SURFACE WITH "DRY EYE" SYNDROME
Authors: Voskresenskaya L.K. , Ryadnova V.V. , Maksimuk O.Yu. , Steblovska I.S. , Voskresenskaya A.V.
Published: July 2020

According to recent studies, the prevalence of dry eye syndrome makes up 14% of cases in patients under the age of 50 years and 65-75% in patients over 50 years of age. Risk factors for the development of dry eye syndrome include aging, stress, side effect of frequent instillations of eye preparations, exposure to radiant energy, and diabetes mellitus. Therefore, the purpose of this study is to investigate the possibility of using “Delargin”, an antioxidant medicine, in the treatment of dry eye syndrome. 50 patients (100 eyes) aged 30-70 years were examined at the Department of Ophthalmology and then divided into three groups depending on the treatment used. Group 1 included 10 patients (20 eyes), who were prescribed to instil Oksial eye drops. Group 2 included 10 patients (20 eyes), who received basic therapy by instilling a solution of sodium salt of hyaluronic acid 0.0015 g / ml. Group 3 involved 20 patients (40 eyes), who instilled Delargin and hyaluronic acid. Monitoring the effectiveness of the treatment was carried out using the following methods: to assess basal tear production, a Schirmer 1 test was performed using the Ophthalic Test diagnostic bands (India); a Norn test was performed to control the stability of the tear membrane. Fluorescence test (staining of the cornea with 1% sodium fluorescein solution) was applied to detect corneal defects; Lipcof test was used to assess the degree of lid-parallel fold formation of the bulbar conjunctiva relative to the costal margin of the lower eyelid. As a result of the treatment, the patients of the Group 1 demonstrated that the Norn test scores increased to some extent from 6.8 ± 0.1 s up to 7.5 ± 0.1 s; in the patients of the Group 2 following the treatment, it was 8.5 ± 0.2 s and in the Group 3, the Norn test values were 11.2 ± 0.2 s (P<0.05). The frequency of blinking movements decreased significantly and approached the normal. It has been found out that the therapy of dry eye syndrome that includes the antioxidant Delargin, can significantly promotes normalizing of parameters typical for this process.
ROLE OF INDIVIDUAL HYGIENE IN TREATMENT OF PATIENTS WITH DENTURE-RELATED STOMATITIS
Authors: Bublii T.D. , Dubovaya L.I.
Published: July 2020

Removable orthodontic appliances can be among the causes of microbial irritation in the oral cavity. The aim of the present study was to assess the oral hygiene status of patients with denture-related stomatitis. We carried out comprehensive dental checkup of 17 patients aged 51 to 69 years with denture-related stomatitis was performed. A bacterioscopic laboratory examination was performed for all patients. The denture hygiene index by E. Ambjörnsen has been determined. Denture-related stomatitis of the patients examined was manifested by various clinical signs. The species composition of the oral microflora when wearing removable dentures deviated from normal values. The Candida fungi were revealed in 13 (76.47%) cases; actinomycetes were recorded in 7 (42.2%) cases. We found that 82.35% of the patients with manifestations of denture-related stomatitis did not follow adequate oral hygienic. The study has shown that 3 (17.64%) cases were assessed as having satisfactory hygienic status. Poor denture hygiene (HI = 2.66) was observed in 5 (29.41%) of the cases. The unsatisfactory hygienic status of the dentures was recorded in 9 (52.94%) of cases and averaged 2.2. 15 (88.23%) patients were unaware of the importance of proper denture cleaning and did not use the hygiene algorithm in full. 3 (17.76%) patients did not did not remove dentures at nights, all the patients did not have a special double-sided brush. Only 5 (29.41%) of the respondents used dental elixirs fro mouth rinsing on regular basis. The results have demonstrated the importance of regular adequate care of dentures and strict adhering to an individual hygiene algorithm in full in order to prevent the occurrence of inflammatory processes in the oral cavity. The prevention is a key approach in the prophylaxis of side effects, which might be caused by dental appliances.
CLARIFICATION OF DIAGNOSTIC CRITERIA FOR SYSTEMIC LUPUS ERYTHEMATOSUS
Authors: Abrahamovych U. O. , Abrahamovych O. O. , Nadashkevych O. N. , Svintsitsky A. S. , Synenkyi O. V.
Published: July 2020

The diagnostic criteria for systemic lupus erythematosus were first proposed in 1971 by the American College of Rheumatology. Though they have been revised several times (in 1982 and 1997), but, according to the information in the literary sources and our own clinical experience, the diagnosis may often be obvious, but the number of criteria is not sufficient and vice versa. This study aimed at improving diagnostic criteria for systemic lupus erythematosus (SLE). Materials and methods. 370 subjects (331 women, 89.46%, and 39 men, 10.54%, whose mean age was 41.24 ± 0.63 years) with confirmed diagnosis of systemic lupus erythematosus made up the main group. The comparison group included 234 patients (150 women, 64.10%, and 84 men, 35.90%), whose mean age was 48.82 ± 0.85 years) diagnosed to have rheumatic diseases (rheumatoid arthritis, psoriatic arthropathy). Through the period of 2010 – 2018 all the participants were subjected to comprehensive clinical laboratory and instrumental examination of all their organs and systems before starting the treatment. The obtained data were analyzed by MS Excel and SPSS by contingency tables with the calculation of diagnostic and prognostic values ​​(the relationship was considered to be significant if the absolute value of association coefficient exceeded 0.5 or the absolute value of the contingency coefficient exceeded 0.3) and Receiver Operating Characteristic-analysis. Results. The statistical analysis allowed us to identify 14 criteria comprising 18 manifestations that indicated systemic lupus erythematosus with confirmed highest sensitivity, specificity and accuracy. They include butterfly rash, photosensitivity, serous inflammation (pericarditis, pleuritis), joint pain, muscle pain, fever, alopecia, Raynaud syndrome, livedo reticularis, nervous system impairment (cramps, psychosis), thrombocytopenia, kidney damage (proteinuria, cylindruria), anti-dsDNA antibodies, antinuclear antibodies. These criteria are highly predictive; the combination of arthralgias and the presence of anti-dsDNA antibodies allows to predict the diagnosis of systemic lupus erythematosus in patients with an almost 100% certainty. To be diagnosed with systemic lupus erythematosus, patient has to meet at least three of the 14 proposed diagnostic criteria that would occur simultaneously or one after another in any period. Conclusion. We have clarified diagnostic criteria for systemic lupus erythematosus by identifying 14 criteria as follows: butterfly rash, photosensitivity, serous inflammation (pericarditis, pleuritis), joint pain, muscle pain, fever, alopecia, Raynaud syndrome, neurological disorders (cramps, psychosis), livedo reticularis, thrombocytopenia, kidney damage (proteinuria, cylindruria), anti-dsDNA antibodies, and antinuclear antibodies.
EARLY HIP REPLACEMENT IN PATIENTS WITH FEMORAL NECK FRACTURES
Authors: Nasirli J. A.
Published: July 2020

The aim of the study was to improve the surgical treatment outcomes for hip fracture by optimizing the methods of preoperative preparation for endoprosthesis, choosing the method of endoprosthesis and postoperative management of elderly and senile patients.

The study was based on the analysis of the treatment outcomes of 339 patients with femoral neck fractures, aged 50-85 years for 2000-2019. 206 patients underwent endoprosthetic surgery without cement fixation; in 133 cases bone cement was used. 151 (44.8%) patients had total hip replacement with Deriuh and Zimmer implants performed within 1 to 2 days. 66 (19.5%) patients underwent surgery within 5 days, and the remaining 120 (35.5%) patients underwent endoprosthetic surgery within 8-10 days. When diagnosis has been made, the patient should undergo endoprosthetic surgery as early as possible. Preoperative preparation of this group of patients, in addition to standard procedure, also included the dopplerography, densitometry, and biochemical blood tests to determine the level of calcium. Summing up these diagnostic parameters, the severity of osteoporosis was determined that in turn allowed clinicians to choose the optimal tactics for hip replacement. The average duration of the operation was about 1 hour. In the postoperative period, patients were monitored in the intensive care unit for a day. A day after the operation, the patient can move relatively freely in bed. He can be allowed to sit down if he can. It is necessary to perform deep breathing exercises. Movements in the knee joint can be started from the first day. Next day, depending on the general condition, the patient can be allowed to sit on a chair near the bed or even walk with crutches. Before getting patients on their feet on the 2-3 day after the operation, dopplerography is performed. Walking with crutches lasts 2-3 days, but patients should not avoid the load on the operated limb; after this period the patient should walk with a stick, and in a few days without a stick. Walking with additional support is recommended for up to 10 days. The average period of inpatient treatment of this group of patients was up to 12 days. 151 patients, who had endoprosthetic surgery performed on within 5 days, had no hypostatic complications, thrombosis and thromboembolism; 3 patients were found to have cardiovascular insufficiency and one patient had bedsores. In 188 patients who had hip replacement performed on in 5 days and over since the fracture, the percentage of complications was as follows: hypostatic complications thrombosis and thromboembolism was found in 3 cases, heart failure – in 4 cases, bedsores – in 7 cases. Hip replacement in femoral neck fractures in the elderly and senile age should requires as early intervention as it possible thus, providing the main prevention of hypostatic complications and early rehabilitation of patients.
EVALUATION OF HORMONAL ASPECTS BY CERVICAL INSUFFICIENCY IN WOMEN WITH HISTORY OF INFERTILITY
Authors: Perkhulyn O.M.
Published: July 2020

Introduction. Today, the frequency of infertility is increasing worldwide. Infertility, associated with anovulation, is especially challenging for the medical correction especially. The leading aspect of this problem is hormonal disorders in the body of a woman. The aim of this study was to assess the level of estradiol and progesterone in the blood serum of pregnant women with cervical insufficiency and infertility associated with anovulation in the history. Materials and methods. The main group included 30 pregnant women with the II trimester of pregnancy, who had cervical insufficiency and infertility associated with anovulation in the past medical history. They got pregnant after assisted reproductive technologies. The control group included 30 pregnant women without cervical insufficiency and with physiological gestation. Estradiol and progesterone levels in blood serum were determined at 20-22 and 30-32 weeks of gestation. Results. The average age of the women in the basic group was statistically higher relative to the control one – 31.30±1.16 and 27.30±0.92 years, respectively (p=0.02). There was no difference in the number of pregnancies in women between both groups. In the main group, 73.33% of the persons were primagravida, 10.00 % of patients had two pregnancies, and 16.67 % - three pregnancies. 56.67 % of the women in the control group were primagravida, 26.67 % had two pregnancies, 16.66 % - three pregnancies. Although primaparas predominated in both groups, the number of such women was in 1.47 times higher in the main group (93.33 %) than in control (63.33 % of patients; χ2=6.28, p=0.01); 6.67 % and 26.67 % women had two labors respectively and 10.00 % of healthy patients - three labors. The concentration of estradiol at the 20-22 and 30-32 weeks of pregnancy in women of the main group almost corresponded to physiological parameters. However, the progesterone level in women with cervical insufficiency and a history of infertility was by 13.44 % lower than in healthy pregnant women at 20-22 weeks, and by 17.02% at 30-32 weeks (p=0.003). Conclusions. In pregnant women with cervical insufficiency and infertility associated with anovulation, the level of estradiol in the II and III trimesters of gestation mainly corresponds to the level of physiological pregnancy. However, they have the decrease in progesterone concentration in the III trimester of pregnancy relative to healthy pregnant women (p<0.003).
The impact of the IPA cross-border co-operation Hungary - Croatia 2007 – 2013 programme - infrastructure, tourism and human capital
Authors: Ravlić Sanela , Glavaš Jerko , Šimunić Mislav
Published: July 2020

The main purpose of the paper is to move towards quantification and clear distinction of invested IPA funds in the CBC area of Hungary and Croatia 2007. - 2013. Objective of the paper is to provide an insight into the real impact of allocated financial resources to the extent that
was not examined so far at the level of institutions (lead beneficiary and project partners) and target group members. The main research questions is what is the impact that implemented projects in IPA CBC HU –
CRO had in terms of different types of institutions, types of activities (educational or infrastructure), beneficiaries in local communities and regional development? The research was conducted in April/May 2018. The questionnaire consisted of 41 variables. Interview was the corrective method. Data analysis was conducted using SPSS v23. Total of 102 respondents participated, representing 358 institutions that implemented projects in the cross-border area. Data were first analysed using descriptive statistics, then compared by using t-test and
ANOVA Chi-square test was performed to determine the likelihood of correlation between variables. Paper shows obtained results on personal,
organisational and regional level. The outcome confirms the difference between human capital in institutions that implement projects and high dependence of EU funds in entire region. Beneficiaries are more aware of
impact that lifelong learning activities can have on their labour market competitiveness. Investment in sustainable environment, tourism, development of economic cooperation, infrastructure and common human capacities will have a significant impact in the region.
Artificial neural networks in modelling seasonal tourism demand - case study of Croatia
Authors: Gregorić Maja , Baldigara Tea
Published: July 2020

The purpose of this paper is to design an artificial neural network in the attempt to define the data generating process of the number of German tourist arrivals in Croatia considering the strong seasonal character of empirical data. The presence of seasonal unit roots in tourism demand determinants is analysed using the approach developed by Hylleberg, Engle, Granger and Yoo – Hegy test. The study is based on seasonality analysis and Artificial Neural Networks approach in building
a model which intend to describe the behaviour of the German tourist flows to Croatia. Different neural network architectures were trained and tested, and after the modelling phase, the forecasting accuracy and model performances were analysed. Model performance and forecasting accuracy evaluation was tested using the mean absolute percentage error.
Based on the augmented HEGY test procedure it can be concluded the German tourist arrivals to the Republic of Croatia have nonstationary behaviour associated with the zero frequency and seasonal frequency. Taking this into consideration, in the

analysis of the phenomenon it is necessary to consider its seasonal character. Given the importance of the tourism for Croatian economic development, the research results could be useful, for both, researchers
and practitioners, in the process of planning and routing the future Croatian hotel industry development and improvement of business performances.
Profitability
performance under capital structure and other company characteristics
Authors: Karanović Goran , Štambuk Ana , Jagodić Davor
Published: July 2020

The main objective of this paper is to explore how capital structure and
other financial characteristics of companies influence Croatian hotel industry performance. This study’s key goal is to analyze the debt-equity structure of hotel industry and to demonstrate its correlation with financial performance. The high significance and impact
of hotel industry on the economy in Croatia was main reason why authors
opted to investigate it. This study was carried out using panel data methodology on a sample of 19 Croatian hotel companies listed on the Zagreb Stock Exchange during the period of 2003-2017. Return on assets and return on equity were used as performance proxies and dependent variables. Twelve variables as capital structure measures and other company characteristics – cash ratio, current liquidity ratio, structure
ratio, debt ratio, debt factor (in years), equity to non-current assets, total assets turnover, current assets turnover, accounts receivables, activity ratio, return on revenue and crises during the 2009-2015 period – were used as independent variables. The findings suggest that cash ratio, structure ratio, debt factor (in years), equity
to non-current assets, total assets turnover, activity ratio, accounts receivables, return on revenue and crises in the 2009-2015 period are related to the financial performance of the Croatian hotel industry. Although profitability performance theory and influence of capital structure and other company characteristic on it is widely studied in financial literature, there are not many studies examining the hotel industry, especially in Croatia. Finally, this study should provide managers with additional insights in making optimal financial decisions.
Utjecaj poreza na dobit na kretanje izravnih stranih ulaganja u zemljama članicama Europske
unije
Authors: Banović Igor , Blažić Helena , Drezgić Saša
Published: July 2020

Većina raspoloživog kapitala nalazi se u posjedu pravnih osoba, odnosno poduzeća (najčešće multinacionalnih kompanija) sklonih ulaganju u širenje vlastitog poslovanja, što ne donosi samo dodatno uvećanje profita poduzeća, već indirektno utječe i na povećanje zaposlenosti, rast gospodarstva, razvoj domaćeg financijskog tržišta te općeniti napredak države. Zato države širom svijeta aktivno utječu na formiranje povoljnog poslovnog okruženja koje će imati učinak na povećan priliv izravnih stranih ulaganja (Foreign Direct Investments – FDI). Cilj ovog rada je utvrditi utjecaj oporezivanja dobiti na privlačenje izravnih stranih ulaganja u zemljama članicama Europske unije. Statička panel analiza provedena je za razdoblje od 1998. do 2017. godine na 28 zemalja članica u cjelini, te posebno na starim članicama (EU 15) i novim članicama (EU13). Uz različite kontrolne varijable, kao nezavisna varijabla analizirane su različite stope poreza na dobit – zakonska (službena, nominalna) stopa poreza na dobit i efektivne (prosječna i granična) porezne stope u cilju ispitivanja stvarnog poreznog opterećenja trgovačkih društava i njihovog utjecaja na kretanje izravnih stranih ulaganja. Zaključeno je kako porez na dobit značajno utječe na kretanje izravnih stranih ulaganja trgovačkih društava u novim zemljama članicama
Europske unije (koje karakterizira niže porezno opterećenje), ali ne kao primarni čimbenik, pri čemu se ističe društveni proizvod. U tom kontekstu najveći utjecaj ima efektivna prosječna porezna stopa.
Mišljenje proizvođača ekoloških prehrambenih proizvoda o mogućnostima razvoja ekološke poljoprivrede
u Hrvatskoj
Authors: Šugar Tina , Brščić Kristina , Kocković Zaborski Tanja
Published: July 2020

U posljednjih nekoliko godina zabilježen je trend rasta površina pod ekološkom proizvodnjom u Hrvatskoj. Razvoj ekološke poljoprivredne proizvodnje sve je više potican kao model proizvodnje koji je od presudne važnosti za očuvanje najvažnijih prirodnih resursa u proizvodnji hrane, u Hrvatskoj i Europi. Cilj rada bio je utvrditi mišljenja ekoloških proizvođača o ograničenjima i mogućnostima razvoja ekološke poljoprivrede u Hrvatskoj. U članku su predstavljeni rezultati istraživanja provedenog na manifestaciji “Pazi što jedeš” održanoj u Puli 2015. godine. Sudionici su bili izlagači na sajmu, proizvođači ekoloških prehrambenih proizvoda iz Hrvatske. U istraživanju je sudjelovao 41 proizvođač ekoloških proizvoda. Glavni rezultati studije odnose se na opće informacije o proizvodnji ekološke hrane, vrstama proizvodnje i načinu distribucije. Također, dobiveno je mišljenje proizvođača o najčešćim problemima koji se javljaju u ekološkoj proizvodnji hrane. Rezultati mogu poslužiti kao informativna podloga o stajalištima proizvođača o problemima proizvodnje ekološke hrane kao i za kreiranje budućih aktivnosti u cilju jačanja ekološke proizvodnje u Hrvatskoj te kao podloga za kreiranje budućih istraživanja.
The influence of entrepreneurship in youth unemployment in transition and MENA countries
Authors: Sulejman Rejhan
Published: July 2020

Even though young people do not have enough work experience and skills, there is no doubt that they are an important source of the economic growth. However, the integration of young individuals to the labor market faces difficulties because of the missing experience, so one of the tools used to integrate them easily in the market has been entrepreneurship. In the last decade the concept ‘entrepreneurship’ and ‘entrepreneur’ have become very popular especially among youth. Studies show that young people are becoming interested in start-up businesses because they think about what they can do for themselves instead of what
the government can do for them. The aim of this paper is to identify the relationship of entrepreneurship with youth unemployment in transition and Middle East and North Africa (MENA) countries for the period 2008 – 2016. An econometric analysis of panel data for the 33 countries is executed in Stata 12, to identify whether entrepreneurship can be used as a tool to decrease youth unemployment. There is no universal method to measure entrepreneurship, so data collected from different countries can bring incorrect results. In order to avoid incorrectness and misleading results we use TEA (total-early stage entrepreneurial activity) for entrepreneurship, from the Global Entrepreneurship Monitor, which uses the same methodology for data collection in every country. This study proves the theories from the literature review stating that young people have ambitions and are interested in starting their own business.
What is the
relationship between FDI and economic growth? Evidence from EU15 countries
Authors: Bilas Vlatka
Published: July 2020

The aim of the paper is to examine the relationship between foreign direct investment (FDI) and economic growth in EU15 countries over the period 2002-2018. EU15 makes a group of countries which entered the EU prior to the biggest enlargement in 2004, namely latest in 1995 (Austria, Belgium, Denmark, Finland, France, Germany, Greece, Ireland, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and United Kingdom). Paper findings contribute to the existing literature on the impact of FDI on economic growth. It employs different unit root tests, panel cointegration test (ARDL model) and Granger causality. Estimated panel ARDL model found some evidence that there are long-run equilibrium
between LogGDP, LogFDI and LogFDIP series. The rate of adjustment back to equilibrium is between 4.43% and 5.95%. The long-run coefficients are
all positive, but not all of them are statistically significant. In case of LogFDIP series long-run coefficients are statistically significant, varying between 0.1226 and 0.4398. These coefficients indicate that 1% increase in LogFDIP (logarithm of FDI to GDP) increases
LogGDP between 0.1226% and 0.4398%. Results of Dumitrescu-Hurlin panel causality test indicated that there is only unidirectional causal relationship from GDP growth rate to FDI growth rate, and from GDP growth rate to LogFDIP. Conclusively, there is only a weak evidence that
FDI had statistically significant impact on the GDP in EU15 countries.
Implementation of UAV Communication Channel Using Airborne Wide-Band Low-Element Antenna Arrays
Authors: Korovin K. , Kuzmin S.
Published: July 2020

In this paper, we consider the the possibility of constructing a long-range communication link using a broadband low-element cylindrical antenna array based on Vivaldi antennas in 10 GHz band. A comparative analysis of the choice of emitters, optimization of the system according to the ratio of the number of elements and gain, and the assessment of overall characteristics are carried out. It is shown that the use of low-element cylindrical array allows one to obtain a compact antenna system with a gain of 13–16 dB, which allows one to construct a long-range communication channel.
Characteristics and Parameters of Land Mobile Service Units Necessary for EMC Analysis in Shared Frequency Bands: Analytical Survey
Authors: Antipin B. , Vinogradov E.
Published: July 2020

The analysis of frequency bands allocated among radio services in the Table of frequency allocations reveals that every band is utilized by several different radio services. The sharing of frequency bands by radio services requires that electromagnetic compatibility of the radio electronic equipment belonging to these services shouldbe ensured. Currently there is a rapid development of land mobile radio communication systems. There are concidered the basic parameters of radio transmitters and radio receivers belonging to ATP systems, which are necessary for the electromagnetic compatibility analyzing of such systems between themselves and with other systems sharing a certain frequency band. We can observe ways of using some characteristics.