bluuebunny/crossref_metadata_2025 huggingface dataset:
A Bibliometric Analysis of COVID-19 Research in Malaysia using Latent Dirichlet Allocation
Authors: Zamzuri Zamira Hasanah
Published: July 2021

Coronavirus COVID-19 shocking the whole world due to its highly contagious characteristics implicating not only public health, but also economy and social life. Since the effects are momentous, plenty of research have been conducted and still ongoing in order to study and to learn more about this virus and how it changing our daily life. In this paper, we explore 134 articles published in 2020 related to COVID-19 and narrowing the scope of study to Malaysia. An alternative route was taken by employing Latent Dirichlet Allocation (LDA) to identify underlying themes or topics in these publications. Two separate analyses were conducted, one is to the paper’s titles and another one to the journal’s names. The findings identified three topics for paper’s titles data are clinical study, impact of COVID-19 on various fields and Movement Control Order (MCO). The last topic shows the locality criterion in the studied papers as the term MCO was only used in Malaysia. For the journal’s names, three topics identified were medical study, public health also business and education. Two papers with the most number of citations are both in social sciences. Investigating the properties of these topics, we found that papers on clinical studies are the ones with more chance to be cited and published by reputable publishers. These findings may help researchers on planning and strategizing for future research on COVID-19 specifying on Malaysia cases.
Detection of Prostate Cancer in Patch-Level Gleason Grading using Deep Learning
Authors:   , Tan Wenhan , Breen David E.
Published: July 2021

With more than 1 million diagnoses reported each year, prostate caner becomes one of the most common cancers among males. Whole slide images are examined by pathologists and scored according to the Gleason grading system. In this thesis, a deep learning system focused on patch-level Gleason grading is presented. This system generates patch-level results first and predicts a mask image for each prostate cancer slide. Patch-level classification is done under a decision flow method and a normal multi-class neural network method. The decision flow iteratively filters out areas from benign to most severe using 4 separate models. The generated mask images contains regional information regarding cancer severity for each biopsy. Each predicted mask image is then aggregated into a prognostic grading group that determines clinical decision thresholds of treatments. This work achieves similar slide-level results compared to previous works and is able to predict additional mask images for clinical practice.
Rethinking the Narrative in Fe en Disfraz: Latin American Female Slave Stories from Violence to (Self)-Emancipation
Authors: McClanahan Joseph
Published: July 2021

As with her previous novels, Mayra Santos-Febres explore the often-complex (inter)connections between men and women in Fe en disfraz (2009). In this novel, she takes her readers on a historical exploration into Latin America’s Colonial slave past, intertwining this history with the 21st century. The novel revolves around two Caribbean historians, who are living and working in Chicago, María Fernanda Verdejo, known as Fe, and Martín Tirado and serve as guides on this journey linking the present-day to the past. Through an entanglement of stories, relationships, and historical reflections, Santos-Febres creates a distinctive narrative which helps the reader on this literary expedition. As such, this article addresses how the author’s narrative style combined with reverberations of a bleak period in Latin American history come together to re-contextualize the violent female slave narratives in order to focus on their emancipation, and ultimately, to reveal how the central character vocalizes her own desire to be emancipated from these echoes of the past.
The belated implementation of a long-awaited health system in Cyprus and the role of interest groups
Authors: Alexandrou Denise , Kantaris Marios , Theodorou Mamas
Published: July 2021

It is really a paradox that 60 years were required to establish a modern health system in Cyprus, despite the expressed positive attitude οf all political parties and most governments. This article investigates the planning and implementation of the National Health System (NHS) and its delay determinants, by employing qualitative research of published sources, audio material and 33 interviews with elite key informants. A major anti-reform alliance, consisting of private doctors, private hospitals and health insurance companies was identified, further supported by doctors of the “old” public system, whose benefits were threatened. Delay contributions additionally arose from media and patient groups, whilst the pharmaceutical sector imposed insignificant influence. Τhe prevailing political, economic and social environment, along with aspects of the proposed reform, fueled this anti-reform movement. However, climate in favour of the NHS implementation gradually developed, attributed to the power balance shift supportingthe Minister of Health and the government, mobilization of important actors/stakeholders, including the Federation of Patients' Organizations of Cyprus and the Media, and significant decrease in the influence of reform-resistant groups. The new dynamics created a supportive environment leading to the NHS launch on June 1st, 2019; thus Cyprus has ceased to be the last state of the European Union (EU) without a universal health coverage system. The process of introducing this new system in Cyprus is a prime example of resource and power redistribution amongst different interest groups and of the catalysts required to exit the orbit of an extremely “path-dependent” system, potentially inspiring future reformers.
History of Trypanosomosis in the One-Humped Camel and Development of its Treatment and Cure, with Special Reference to Sudan
Authors: Wilson R , Dioli Maurizio
Published: July 2021

Sudan has one of the largest populations of domestic animals in Africa. One-humped camel (Camelus dromedarius) numbers were estimated at 4.5 million in 2009. Once used extensively for military transport they are still used in the transport role by spatially mobile pastoralist households and are a major source of milk and meat for these people. Trypanosomosis, due to Trypanosoma evansi, generally known as ‘surra’ but as ‘gufar’ in Sudan was first identified in camels in the country in 1902 and is the main cause of disease although T. vivax infections have recently been discovered in parts of Sudan. This protozoan disease is the most important health problem in camels, causing high morbidity and huge production losses. The causal organism, unlike most other trypanosomes, is not transmitted cyclically with tsetse (genus Glossina) flies as the vector but mechanically by biting flies mainly family Tabanidae but also by others of the Muscidae. Identification of the parasite in camel blood was initially by simple microscopic techniques but biotechnology and molecular methods now enable infection to be diagnosed at an earlier stage and with more accuracy. Prophylactic and curative treatments of trypanosomosis are notoriously complicated and uncertain with the situation in camels being exacerbated because of its peculiar physiology. Many trypanocides have been developed over time but the parasite often develops resistance to these drugs. Some drugs are successful, for some time, as both prophylactics and cures but are often accompanied by undesirable side effects. Other drugs used on conventional domestic stock are ineffective in camels or have lower efficacy. Research on diagnosis and treatment of trypanosomosis is continuing but the disease continues to cause production losses to the detriment of national and household incomes and food security.
Reflextherapy in Healthcare – Reflection on Audit Result and Employment of Therapy
Authors: Berry Gunnel
Published: July 2021

An article was published in 20141 reporting on an audit of the Membership of the Association of Chartered Physiotherapists in Reflextherapy (ACPIRT). This article reflects on the outcome of the audit in the context of a treatment tool in physiotherapy and allied health professions in the United Kingdom and abroad. Background: ACPIRT was established in 1992 by Christine Jones, physiotherapist, and associated colleagues to provide a clinical interest group for physiotherapists and allied health professionals practising reflextherapy (RT), a manual therapy applied to the feet (or hands) similar and akin to reflexology. The audit was carried out in 2009 to establish a professional profile of members and to document their clinical experiences in using RT in healthcare. Methodology: 161 ACPIRT members were sent a postal questionnaire (including a stamped return envelope) regarding their experience using RT treating patients in the NHS and/or in private practice. One hundred (62%) members responded. A pilot study was carried out prior to the main enquiry including 14 ACPIRT committee members. Their results were included in the final audit result. Aims: i) To describe members’ demographics, work environments and opinions of the value of RT in healthcare. ii) To describe the historical background and development of RT to become an accepted therapeutic intervention by the Chartered Society of Physiotherapy. Results: Sixty-eight respondents (68%) considered RT ‘very good’, ‘good’ and ‘as good as’ orthodox physiotherapy. Fifty-eight respondents (58%) thought RT had a 25% placebo effect. No one considered RT to have a 100% placebo effect. Overwhelmingly, 95 respondents (95%) reported ‘relaxation’, ‘reduced stress’ and ‘reduced pain’ as main benefits of the treatment. A few respondents reported ‘increased fertility’, ‘improved bowel function’ and ‘reduced appetite’. Comments were made on the future of RT and recommendation for a Foundation Course. The results showed a mature, highly experienced professional membership with a female gender bias.
Assessment of mental health status among adolescent school children in Karnataka
Authors: Srividya J  , Patel Apoorva E , Kumar D R Sunil , Suresh V C
Published: July 2021

India has the largest population of adolescents in the world (1/5th of world’s adolescents)with4-33% prevalence of mental health disorders. The present study was conducted to assess the mental health status of adolescent school going children in Karnataka.

A cross sectional study was conducted among 375 adolescent school going children aged 10-15 years in a private school in Karnataka (June-August 2019). Students were interviewed by pretested questionnaire after obtaining informed assent from the school administrators and primary care givers. The questionnaire included 4 different domains viz., Educational, Physical health, Emotional and Social factors. Scores ranged between 0 – 41 and interpreted as higher the scores better the mental health status of student. Data was analyzed using SPSS software version 24.

Out of 375 participants, 48.8% were girls and 51.2% were boys with mean age of 12.7 yrs. Overall 12.5% students had abnormal mental health status, which was more among girls (15.4%) compared to boys (9.9%) and it was statistically significant (p < 0.021). Of 4 domains, physical health factor was most affected (17.3%), followed by educational factor (15%). Gender-wise, educational domain was most affected among boys (17.7%, p = 0.034) and physical health domain among girls (20.2%, p<0.001), which was statistically significant.

This study shows that abnormal mental health status is prevalent among adolescents and more among girls. Of the 4 domains, Physical health was most affected. This problem needs addressal with well defined school-based intervention programs.
Three dimensional technique of imaging in orthodontics: A review
Authors: Sheoran Lalita , Ul Sadiq Nasir , Hussain Farhan , S Gupta Akshun , Tousif Ulla Syed , Manzoor Zahid
Published: July 2021

The process of deploying the two dimensional data in to the three dimensional format is three dimensional imaging. Now a days three dimensional imaging is developing as an emerging factor in the field of dentistry. Three dimensional imaging is useful in the field of orthodontics, to view the anatomy along with the morphology of the bone for desired tooth movement, it is useful in the field of prosthodontics to check or verify the bone morphology, exact height and width of the bone for the process placing implant, three dimensional imaging is quite useful in the field of endodontics along with oral surgery to view the anatomy of the root curvature, to confirm the presence of accessory canals to confirm the bony architectural defect in oral surgical procedures. So in present days three dimensional imaging plays an important role in diagnosis as well as treatment planning in the field of dentistry.
Modified TPA appliance for severely proclined central incisors
Authors: Dhingra Richa , Azam Aftab , Chauhan Ashish , Tandon Ragni , Mathur Pranshu
Published: July 2021

The esthetic appearance of teeth forms a part of an overall picture, interacting closely with facial esthetics. The patient’s esthetic expectations were successfully met through a comprehensive approach of severe proclination by tipping the maxillary central incisors. Here, we are showing a novel approach to bring about uncontrolled tipping to decrease the inclination of severely proclined teeth.
Nuevos registros de Aphodiinae (Coleoptera, Scarabaeidae) en Colombia
Authors: Clavijo-Bustos Julián , Bacca Tito , Canal Nelson A.
Published: July 2021

En este estudio se presentan los resultados de un monitoreo de los escarabajos Aphodiinae (Coleoptera: Scarabaeidae) realizado con una trampa luminosa Pennsylvania-Minnesota con luz UV en el Centro Universitario Regional del Norte de la Universidad del Tolima en Armero Guayabal, Tolima, Colombia. Se recolectaron 21 especies/morfoespecies, cinco de ellas son nuevos registros en Colombia: Ataeniopsis regulus (Balthasar, 1947), Euparia mirabilis (Balthasar, 1945), Euparixia isthmia Gordon & McCleve, 2003, Lomanoxoides nigrolineatus (Hinton, 1938) y Saprositellus santaritae Stebnicka, 2003. Se obtuvieron registros adicionales en el país de estas especies a partir de la revisión de colecciones entomológicas colombianas. Estos nuevos registros aumentan la riqueza de Aphodiinae en el país a 61 especies y 25 géneros.
An Image of God for the Future of Europe
Authors: Duque João Manuel
Published: July 2021

The article intends to explore the possible impact of the image of God originated in Judaism and Christianity on some elements of the configuration of Europe, in an essentially cultural perspective, although with also political effects. It is not intended to assess this impact only within Christian or Jewish communities, that is, in relation to the believers of these religious traditions. It is intended to extend this impact to European society, as such, since the effect of this image of God can also refer to non-believers, especially in the way they interpret their daily lives and their social structures. It is not, therefore, about the recovery of a theocratic system, but about the possibility of effects of the reference to God, as if God did not exist.
The Relationship between Theology and Law on the Basis of the Encyclical Pacem in terris of John XXIII
Authors: Grzenkowitz Mikołaj
Published: July 2021

The above research permits one to draw legal and theological conclusions. The first sub-point, presenting the legal value and social-political context of the papal teaching, permits the creation of a foundation for the following theological considerations. The second subpoint permits for the separation of the theology of the encyclical and its meaning for the whole document. The last sub-point reveals in what way the legal and theological elements intersect in the encyclical’s text and what consequences this has for ecclesiology and the methodology of research at the intersection of theology and law. This article presented many mutual points of reference for theology and law and emphasized their methodological and substantive autonomy. The encyclical Pacem in terris of John XXIII is a creative proposal for the cooperation between theology and law, in which the Pope follows the principle of efficacy, which is the desire that the catalogue created by him is not only theoretical but also actually used. His teaching focuses on the theme of peace, which seems to assume the meaning that has already placed on justice, and the Pope seems to make it the centre of all international relations. That, in turn, allows to distinguish peace as a clearly legal category and so decisive for the just character of law itself. Because of the connection between peace, God’s order and Christ’s mission, there is a perfect intersection between temporal matters regulated by law and supernatural ones, which are the subject of theology. There exist two alternative models of the unity of humankind: the natural and the ecclesial. They have a complementary character as the two paths leading to a common goal and take the form of attaining the commonly desired peace on earth and the unification of humanity in Christ, who is peace himself. The Pope uses legal language, which has characteristics manifesting the openness of theology to law and vice-versa. Among them are cognitive realism, universal concepts, universal themes, social efficacy, legal naturalism, and mutual inspiration.
Avaliação da ingestão de antioxidantes em doentes renais crônicos em hemodiálise com e sem o diagnóstico de diabetes mellitus
Authors: Luzzi Maria Teresa Knaut , Teixeira Jociane De Lima , Schiessel Dalton Luiz , Cavagnari Mariana Abe Vicente , Franco Silvana , Castilho Aline Jabur , Mazur Caryna Eurich
Published: July 2021

Introdução: Na doença renal crônica (DRC) os rins que não conseguem realizar suas funções, e pode estar associada ao diabetes mellitus (DM). Os antioxidantes diminuem o estresse oxidativo e processo inflamatório, podendo melhorar o prognóstico da DRC, com isso a avaliação da ingestão de antioxidantes é recomendada. Objetivo: Avaliar a ingestão de antioxidantes por uma amostra de pacientes com DRC em hemodiálise com e sem diagnóstico de DM. Métodos: Estudo retrospectivo realizado com 38 pacientes com DRC com e sem diagnóstico de DM. Foram coletados dados dietéticos com recordatório alimentar de 24 horas, foram analisados os valores de vitaminas A, D, E, C e minerais: ferro, magnésio, manganês e zinco, selênio. As análises foram de realizadas por meio dos testes T de Student e Mann-Whitney para verificar se havia diferença de consumo de antioxidantes entre os pacientes. Resultados: A média de idade da amostra foi 49,0±7,6 anos. A maioria era do sexo masculino (63,2%) e 47,4% possuíam diabetes. Pouco mais da metade da amostra (52,6%) possuía o diagnóstico de DRC a mais de 36 meses. A vitamina C diferiu quando comparados os pacientes com e sem diabetes (p<0,05). Nas demais avaliações o consumo de nutrientes antioxidantes não houve diferença entre os pacientes dos dois grupos estudados (p>0,05). Conclusão: Foi possível observar que o consumo das vitaminas A, D e E estava abaixo da recomendação, apenas a vitamina C estava em níveis adequados na maioria dos pacientes avaliados, porém havia divergência do consumo dessa entre os pacientes com e sem DM.
Ações educativas na estratégia saúde da família: tecendo a experiência com grupo de idoso
Authors: Melo de Sousa Francisco Willian , Moreno Amaral Hiara Rose , Vasconcelos Sobrinho Natasha , Carlos Rosa Benedita Shirley , Da Silva Lima Carlos Eduardo , Carvalho Araújo Moreira Andréa
Published: July 2021

Este estudo visou relatar as atividades de educação em saúde realizadas com um grupo de idosos no âmbito da Estratégia Saúde da Família. Relato de experiência referente às ações extensionistas desenvolvidas por discentes de Enfermagem da Universidade Estadual Vale do Acaraú, em uma Unidade Básica de Saúde, localizada em Sobral, Ceará, no período de outubro a novembro de 2019. Para coleta das informações utilizou-se como métodos: a observação participante e os registros das ações educativas em um diário de bordo. Posteriormente, realizou-se a análise das informações através da sistematização e agrupamento das ideias de maneira crítico-reflexiva junto à literatura. Ao todo, realizaram-se oito encontros com os idosos, nos quais desenvolveu-se intervenções educativas, por meio de oficinas, envolvendo os temas seguintes: avaliação cognitiva, relaxamento, musicoterapia, atividade física, alimentação saudável, hipertensão arterial sistêmica, diabetes mellitus, uso racional de medicamentos e direitos do idoso. Evidenciou-se que os participantes se sentiram mais confiantes para o autocuidado e reconheceram a importância de atitudes saudáveis para manutenção da qualidade de vida. A experiência proporcionou aos acadêmicos a aproximação da realidade na perspectiva da abordagem e condução de grupo de idosos, bem como corroborou para produção dos saberes para além do ambiente da sala de aula.
Estimulação transcraniana por corrente contínua uma nova possibilidade terapêutica para o tratamento da fibromialgia: uma revisão de literatura
Authors: De Souza Alessandra Hubner , Rodrigues Juliana Da Silveira , Dos Santos Vinicius Souza , Antunes Flavia Tasmim Techera
Published: July 2021

O presente estudo teve como objetivo avaliar o uso da estimulação transcraniana por corrente contínua (ETCC) como uma nova possibilidade terapêutica para pacientes com fibromialgia, através de uma revisão de literatura. A partir de uma busca eletrônica nas bases de dados Pubmed, LILACS, SciELO e  ScienceDirect, no período de2008 a2018, foram encontrados 48 artigos. Logo, selecionaram-se 9 estudos de acordo com os critérios: estimulação transcraniana por corrente contínua em córtex dorsolateral pré-frontal (CDLPF), córtex motor primário (M1), pesquisa em humanos, ensaios clínicos e estudo cruzado. Estes foram agrupados em três grupos: benefícios clínicos, efeitos adversos e contra-indicações. Os resultados obtidos nesta revisão demonstraram que o principal benefício clínico da ETCC foi à diminuição da dor após a estimulação sobre o córtex motor primário, além disso, percebe-se que o aumento do número de sessões de ETCC está relacionado com efeito duradouro do tratamento. Os efeitos colaterais mais relatados foram coceira, vermelhidão e formigamento no local da aplicação. As contra indicações do uso desta técnica são implantes metálicos na cabeça, histórico recente de neurocirurgia, distúrbios psiquiátricos graves, gravidez e lactação, entre outros. Esta revisão poderá levar a um melhor direcionamento dos resultados relacionados ao alívio da dor, podendo surgir assim uma nova possibilidade terapêutica para os FM.
O acesso à informação em saúde bucal nos portais eletrônicos: o empoderamento do usuário nos municípios
Authors: Nascimento Carolina Carvalho Menez Pinto , Moimaz Suzely Adas Saliba , Saliba Tânia Adas , Saliba Nemre Adas
Published: July 2021

Objetivo: Avaliar o acesso à informação em Saúde Bucal (SB) através da funcionalidade de alguns sites municipais, no que tange à acessibilidade/usabilidade dos sítios; às informações em SB disponibilizadas aos usuários; ao Controle Social sobre a administração; e à interatividade e participação do usuário.Material e Método: Trata-se de um estudo de casos múltiplos, de caráter descritivo-exploratório, tomando os portais dos 26 municípios do estado de São Paulo pertencentes ao Departamento Regional de Saúde XIII (DRS XIII), região administrativa da Secretaria Estadual de Saúde.Resultados: Os resultados mostraram que a maioria dos sítios avaliados apresentaram Índices de Funcionalidade (IF) insatisfatórios. A média do IF dos municípios foi 12,24 e o desvio padrão 3,61, mínimo de 7 - Santa Rita do Passa Quatro e o máximo de 24 – Ribeirão Preto. A funcionalidade de cada dimensão, ofereceu certa confiança em termos de interatividade e participação, entretanto o mesmo não ocorreu para as demais categorias.Conclusão: Conclui-se, que há a necessidade do Estado, de adequar-se não somente às leis vigentes, mas também às demandas da sociedade, modernizando a sua estrutura interna para que os sítios sejam efetivamente interativos e transparentes.
A system architecture for ensuring interoperability in a South African national electronic health record system
Authors: Tsegaye Tamir , Flowerday Stephen
Published: July 2021

ountries such as South Africa have attempted to leverage eHealth by digitising patients' medical records with the aim of improving the delivery of healthcare. This involves the use of an electronic health record (EHR) which is a longitudinal electronic record of a patient's information. The EHR includes all the patient's encounters that have been made with different health facilities. In the national context, the EHR is also known as a national EHR, which enables the sharing of patient information between points of care. However, a lack of interoperability exists between many South African health information systems making communication between these disparate systems impossible. As a result, the sharing of patient information is inhibited and the benefit of improving healthcare delivery cannot be realised. This paper proposes a system architecture for addressing interoperability challenges and indicates how interoperability can be ensured in a national EHR system. The proposed system architecture is differentiated from other national EHR system architectures found in the literature in order to emphasise its novelty. Secondary data obtained from a systematic literature review was analysed using content analysis, resulting in 9482 tags which informed the development of the proposed system architecture.
The Continuum of Information Systems Project Success: Reflecting on the Correlation between Project Success Dimensions
Authors: Joseph Nazeer , Marnewick Carl
Published: July 2021

Information systems (IS) project success has been a perennial bane of many researchers. Although there are short, medium and long-term dimensions to success, the reality is that they are inseparably linked. Time plays a significant role as a stakeholder, such as a project manager who has short-term interests. In contrast, a business executive has long-term interests for the organisation as a whole. Project success is arguably a continuum where each dimension plays a role in realising long-term benefits for the organisation. This research investigates IS projects specifically to understand the argued correlation between short, medium and long-term project success dimensions. A total of 612 valid responses were collected through an online questionnaire. Quantitative analysis through PLS-SEM was conducted to reveal the correlation between success dimensions. The overall implication is that short-term IS project success does not directly correlate with long-term IS project success. However, there is a clear correlation between the time phases of IS project success. This research shows medium-term success mediates the relationship and correlation of short and long-term success. While literature acknowledges the relationship literature, this research confirms this notion and proves a significant correlation between each IS project success dimension over time.
An Analysis of the Attitudes of Family Physicians Towards the COVID-19 Vaccine
Authors: BULCA ACAR Aysima , NUR EKE Remziye , ÖZEN Mehmet
Published: July 2021

Objective: Attitudes of family medicine physicians towards the COVID-19 vaccines will be effective in vaccination rates in the community. Therefore, in this study, we aimed to reveal the opinions of family medicine physicians on the COVID-19 vaccines.

Materials and Methods: The data collection forms prepared for this cross-sectional study were converted into an online questionnaire form and sent to the physicians working as family medicine physicians in different provinces of Turkey between December 2020 - January 2021 via e-mails (GoogleGroups) and communication groups (Facebook, WhatsApp, etc.). The responses of 494 family medicine physicians in Turkey, who were accessible through this method and volunteered to participate in the study, were recorded to be analysed.

Results: The opinion towards which the participants in our study had the highest positive attitude was related to the necessity to provide everyone with the COVID-19 vaccine’, while the most obvious negative attitude was related to the view that the efficacy of the vaccine has not yet been tested sufficiently.

Conclusions: Although a significant majority of family medicine physicians have a positive attitude towards the need for administering the COVID-19 vaccine, more than half have expressed a negative or indecisive attitude towards relying on the statements made about the vaccine and its efficacy, which is said to have been adequately tested. For the desired levels can be reached in terms of vaccination rates, public needs to be informed more on the safety and efficacy of the vaccine.
A Computer-Assisted Diagnosis Tool for Classifying COVID-19 based on Chest X-Ray Images
Authors: YAĞIN Fatma Hilal , GÜLDOĞAN Emek , UCUZAL Hasan , ÇOLAK Cemil
Published: July 2021

Objective: Since COVID-19 is a worldwide pandemic, COVID-19 detection using a convolutional neural network (CNN) has been an extraordinary research technique. In the reported studies, many models that can predict COVID-19 based on deep learning methods using various medical images have been created; however, clinical decision support systems have been limited. The aim of this study is to develop a successful deep learning model based on X-ray images and a computer-assisted, fast, free and web-based diagnostic tool for accurate detection of COVID-19.

Method: In this study a 15-layer CNN model was used to detect COVID-19 using X-ray images, which outperformed many previously published CNN models in terms of classification. The model performance is evaluated according to Accuracy, Matthews Correlation Coefficient (MCC), F1 Score, Specificity, Sensitivity (Recall), Youden’s Index, Precision (Positive Predictive Value: PPV), Negative Predictive Value (NPV), and Confusion Matrix (Classification matrix). In the second phase of the study, the computer-aided diagnostic tool for COVID-19 disease was developed using Python Flask library, JavaScript and Html codes.

Results: The model to diagnose COVID-19 has an average accuracy of 98.68 % in the training set and 96.98 % in the testing set. Among the evaluation metrics, the minimum value is 93.4 % for MCC and Youden’s index, and the maximum value is 97.8 for sensitivity and NPV. A higher sensitivity value means a lower false negative (FN) value, and a low FN value is an encouraging outcome for COVID-19 cases. This conclusion is crucial because minimizing the overlooked cases of COVID-19 (false negatives) is one of the main goals of this research.

Conclusion: In this period when COVID-19 is spreading rapidly around the world, it is thought that the free and web-based COVID-19 X-Ray clinical decision support tool can be a very effective and fast diagnostic tool. The computer-aided system can assist physicians and radiologists in making clinical decisions about the disease, as well as provide support in diagnosis, follow-up, and prognosis. The developed computer-assisted diagnosis tool can be publicly accessed at http://biostatapps.inonu.edu.tr/CSYX/.
Élettartam-kockázat Csehországban és Magyarországon
Authors: Gogola Ján , Vékás Péter
Published: July 2021

Az élettartam-kockázat a vártnál hosszabb élettartamokból fakadó pénzügyi kockázat, mely a nyugdíjrendszereket és az életjáradékokat értékesítő biztosítókat érinti legsúlyosabban. Ezért a jövőbeli halandósági ráták előrejelzése ezen szereplők számára alapvető jelentőségű. Elemzésünkben a magasabb, 65-95 éves életkorokra fókuszálunk, mivel a nyugdíjjal kapcsolatos alkalmazásokat tartjuk szem előtt, amelyekben a hosszú távú pénzáramok bizonytalansága elsősorban az ezen életkorokhoz tartozó halandósági ráták alakulásából fakad.A Human Mortality Database (HMD) adatbázisból Csehország és Magyarország halálozási és kitettségi adatsorait használjuk fel, és megmutatjuk, hogy a jelenlegi tendenciák folytatása esetén a szolgáltatással meghatározott nyugdíjtervek kötelezettségeinek értéke Magyarországon 3,77, Csehországban pedig 4,66 százalékkal fog emelkedni, amennyiben a klasszikus periódus (statikus) halandósági tábla helyett kohorsz (dinamikus) táblát használunk.
A COVID-19 járvány hatásai a magyar biztosítási piacra
Authors: Kelemen Kitti
Published: July 2021

A hazánkban 2020 márciusában megjelent, kínai eredetű koronavírus következményeként kialakult helyzet a gazdaság összes szereplőjére hatással van, és ez alól a biztosítók sem képeznek kivételt. Írásunk célja a biztosítótársaságok üzletmenetét érintő legfontosabb problémák feltárása és az ezekre alkalmazott megoldások bemutatása, ezzel átfogó képet nyújtva a hazai biztosítási piaci gyakorlatról. Kutatást végeztünk a magyar biztosítók szakértőinek körében egy általunk összeállított kérdéssor mentén, amelyet minden esetben kétkörös virtuális beszélgetés követett egy-két hónapnyi eltéréssel, amelynek során a koronavírus várt és tapasztalt hatásait, valamint a kezdeti sokk utáni alkalmazkodás ütemét mértük fel. Törekedtünk minden lényegesnek vélt kérdéskört érinteni a biztosítási operációtól kezdve a szerződésállomány változásán keresztül az értékesítésre, termékekre és riportálásra gyakorolt hatásokig. Cikkünk elsősorban a 2020. május és július közötti felmérés során megismert információkra támaszkodik.
A kötelező gépjármű-felelősségbiztosítás személyi sérüléses kárainak vizsgálata
Authors: Hollósné Marosi Judit
Published: July 2021

Az MNB által létrehozott és működtetett, a hazai kötelező gépjármű-felelősségbiztosítás (kgfb) részletes szerződés- és káradatait tartalmazó Központi Kgfb Tételes Adatbázis (röviden KKTA) adataiból készült az elemzés. A vizsgálat célja annak megállapítása, hogy a károkozó járművek és üzembentartóik főbb adatai, továbbá a káresemény helyszíne milyen összefüggést mutatnak a személyi sérüléssel járó káresemények gyakoriságával és a keletkezett kár nagyságával. A KKTA rendszer adatai alapján vizsgált személyi sérüléses károk kárfelhasználása jelentősen eltér a hazai és a külföldön keletkezett károk között. Ez az összehasonlítás több mutató alapján is átlagosan másfélszeres kárfelhasználást jelent a külföldön keletkezett károk esetében. Nagy az egyes károkra történő kárfelhasználások terjedelme, minden évben előfordulnak néhány ezer forintos, ugyanakkor több száz milliós károk is. Az egyes járműtípusok kárgyakorisága jelentős eltérést mutat, és ebből a szempontból a fiatalok is kockázatosabb közösséget alkotnak.
A pénzbőség nem feltétlenül generál kiugró inflációt rövid távon : Interjú Wieder Gergővel
Authors: Lambert Gábor
Published: July 2021

Wieder Gergő a KPMG szenior menedzsere, a Budapesti Corvinus Egyetemen végzett okleveles közgazdász, a Pénzügyminisztériumnál bejegyzett adószakértő, illetve regisztrált kockázatkezelő. A mesterdiplomája megszerzése óta a pénzügyi, befektetési szektorral foglalkozik. A KPMG pénzügyi szektorral foglalkozó területéhez 2008-ban csatlakozott, 2015 óta a kockázatkezelésre és a területét érintő szabályozásokra fókuszál. Rendszeresen publikál, ad interjút a pénzügyi szektort érintő szabályozási, kockázatkezelési témákban.
Breeding of medicinal and essential oil crops in VILAR: achievements and prospects
Authors: Korotkikh I. N. , Baleev D. N. , Morozov A. I. , Mizina P. G. , Sidelnikov N. I.
Published: July 2021

This review discusses the main methods of breeding material development, the current state, problems and prospects for medicinal and essential oil plants breeding. The relevance of this area has especially increased due to the sanctions, the resulting shortage of medicinal plants and their low quality, which does not meet the requirements of the pharmaceutical industry. To produce a stable plant raw material base, it is necessary to actively develop a breeding process to create new highly productive varieties of medicinal plants resistant to biotic and abiotic environments. In breeding with the use of modern molecular biological methods, related species and generic complexes of the All-Russian Research Institute of Medicinal and Aromatic Plants (VILAR) collection can be involved, where there is extensive original genetic material of medicinal, essential oil, rare and endangered species. In the breeding of medicinal and essential oil crops, traditional methods of individual and individual-family selection, polyploidy, chemical mutagenesis and a combination of methods to obtain original breeding material are still promising. VILAR has created more than 90 varieties of medicinal and essential oil crops, most of which have been approved for use throughout the Russian Federation.
Geografia hotelarstwa [The Geography of the Hotel Industry], Andrzej Kowalczyk, Wydawnictwo Uniwersytetu Łódzkiego, Łódź 2000, ss. 429
Authors: Liszewski Stanisław
Published: July 2021

Academics representing many different fields, including geography, have become interested in hotel services as a result of their recent dynamic development. Hotels are the object of analysis in both the geography of tourism, the geography of services and urban geography. The complex character of the phenomenon raises the question of whether the geography of hotel services should become an independent study area.
The Impact of Covid-19 on Livelihoods and Food Security
Authors: Thompson, John Thompson, John , Ndung’u Njuguna , Albacete Miguel , Suleri Abid Q. , Zahid Junaid , Aftab Rubab
Published: July 2021

Studies of livelihoods and food systems since the start of the global pandemic in 2020 have shown a consistent pattern: the primary risks to food and livelihood security are at the household level. Covid-19 is having a major impact on households’ production and access to quality, nutritious food, due to losses of income, combined with increasing food prices, and restrictions to movements of people, inputs and products. The studies included in this Research for Policy and Practice Report and supported by the Covid-19 Responses for Equity (CORE) Programme span several continents and are coordinated by leading research organisations with a detailed understanding of local food system dynamics and associated equity and livelihood issues in their regions: (1) the impact of the Covid-19 pandemic on livelihoods in sub-Saharan Africa; (2) supporting small and medium enterprises, food security, and evolving social protection mechanisms to deal with Covid-19 in Pakistan; and (3) impact of Covid-19 on family farming and food security in Latin America: evidence-based public policy responses.
ЗНАЧЕНИЕ МИКРОЭЛЕМЕНТОВ В ПИТАНИИ СТУДЕНТОВ
Authors:   Оренбургский государственный университет, Берестова А.В. , Баранова О.В. ,   Оренбургский государственный университет, Попов В.П. ,   Оренбургский государственный университет, Кван О.В. ,   Оренбургский государственный университет
Published: July 2021

Развитие и функционирование молодого здорового организма невозможно без микроэлементов. Недостаток или избыток их в рационе питания может привести к возникновению различных заболеваний, снижению работы центральной нервной системы, что может отразиться на умственной и физической деятельности студента. При исследовании студенческих рационов важно не только выявить поступление каких микроэлементов не соответствует нормам, но и должным образом скорректировать питание в отношении качественного и количественного состава атомовитов. В связи с этим более рациональным и правильным решением данной проблемы являются меры, направленные не только на лечение, но и на профилактику заболеваний. Для осуществления этих мер необходимо регулярно проводить беседы о пользе правильного питания, соблюдения режима питания, чтобы каждый молодой человек осознавал, что его здоровье во многом зависит от него самого.
ВОЗРАСТ-ОБУСЛОВЛЕННОЕ ИЗМЕНЕНИЕ МИКРОЭЛЕМЕНТНОГО ПРОФИЛЯ ЛИМФОУЗЛОВ С УЧЕТОМ ИХ ЛОКАЛИЗАЦИИ
Authors:   Новосибирский государственный университет, Горчаков В.Н. , Колмогоров Ю.П. ,   Научно-исследовательский институт клинической и экспериментальной лимфологии – филиал ИЦиГ СО РАН, Горчакова О.В. ,   Научно-исследовательский институт клинической и экспериментальной лимфологии – филиал ИЦиГ СО РАН
Published: July 2021

Исследовано содержание микроэлементов в регионарных лимфоузлах с учетом локализации и возраста при помощи рентгенфлюоресцентного анализа с использованием синхротронного излучения. Микроэлементный профиль лимфоузлов носит регион-зависимый характер, отражая своеобразие лимфатического региона. Различия в содержании микроэлементов определяют микроэлементный профиль каждого из регионарных лимфоузлов. Брыжеечный лимфоузел имеет максимальное содержание Cu, Se, среднее – Fe, Zn, минимальное – Mn. Трахеобронхиальный лимфоузел характеризуется наименьшим содержанием Fe, Cu, Zn, средним – Mn, Se. Паховый лимфоузел отличает максимальное содержание Mn, Fe, Zn, среднее – Cu, минимальное – Se. При старении меняется микроэлементый профиль лимфоузлов, демонстрируя уменьшение содержания большинства микроэлементов при увеличении Mn. Формируется качественно новый микроэлементный профиль каждого из лимфоузлов при старении, отражая снижение дренажной и иммунной функции лимфоузлов. С возрастом в паховом лимфоузле имеют место относительно высокие показатели содержания Mn, Fe, Zn и наименьшее – для Cu и Se. Брыжеечный лимфоузел отличает высокое значение концентрации Se, среднее – Cu, Zn и низкое Mn, Fe. Трахеобронхиальный лимфоузел характеризуется низким значением содержания Zn, средним – Mn, Fe, Se и высоким – Cu. Полученные резуль-таты доказывают регионарную специфику микроэлементного содержания лимфоузлов в зависимости от региона и возраста.
АЛЬФА-АКТИВНОСТЬ ЭЭГ И СОСТОЯНИЕ ЭЛЕМЕНТНОГО БАЛАНСА В ОРГАНИЗМЕ ПОДРОСТКОВ
Authors:   КФУ имени В.И. Вернадского, Медицинская академия им. С.И. Георгиевского, Евстафьева Е.В. , Залата О.А. ,   КФУ имени В.И. Вернадского, Медицинская академия им. С.И. Георгиевского, Зинченко С.А. ,   КФУ имени В.И. Вернадского, Медицинская академия им. С.И. Георгиевского, Евстафьева И.А. ,   КФУ имени В.И. Вернадского, Медицинская академия им. С.И. Георгиевского, Трибрат А.Г. ,   КФУ имени В.И. Вернадского, Медицинская академия им. С.И. Георгиевского
Published: July 2021

В условиях химического загрязнения среды изменяется баланс между химическими элементами (ХЭ), играющими важную роль в протекании нервных процессов. С целью определения значимости 28 ХЭ в обусловливании базового ритма электроэнцефалограммы (ЭЭГ) обследованы 119 городских подростков 12–14 лет. Химические элементы определяли в пробах волос рентгено-флуоресцентной спекторофотометрией; ЭЭГ регистрировали при трех функциональных пробах в 10 отведениях. По результатам корреляционного анализа определяли нейротропность ХЭ с учетом силы и значимости корреляционных связей содержания ХЭ со спектральной мощностью альфа-ритма. Нейротропность ХЭ была более выражена для токсичных тяжелых металлов при их содержании в пределах условной нормы, в то время как дефицитное содержание эссенциальных ХЭ было значимо главным образом при пробе «открывание глаз».
ЗДОРОВЬЕ ДЕТСКОГО НАСЕЛЕНИЯ, ПРОЖИВАЮЩЕГО В ЗОНЕ ДЕЙСТВИЯ КРУПНОГО МЕДЕПЛАВИЛЬНОГО КОМБИНАТА
Authors:   Областная детская клиническая больница, Киреева Г.Н. , Жуковская Е.В. ,   НМИЦ детской гематологии, онкологии и иммунологии им. Д. Рогачева
Published: July 2021

Проживание на территории с избыточным уровнем химических элементов может сказываться на различных функциях организма на протяжении всей жизни человека. Целью настоявшего исследования была оценка здоровья детского населения г. Карабаша, и контаминации организма обследуемых детей токсичными и условно токсичными химическими элементами. В 2014 г. проведено клиническое обследование 114 детей от 12 до 14 лет, проживающих на территории Челябинской области в г. Карабаше, и исследованы пробы волос на содержание макро- и микроэлементов. Аналитические исследования выполнены в испытательной лаборатории АНО «Центр биотической медицины» методами атомной эмиссионной спектрометрии с индукционно связанной аргоновой плазмой (ИСП-АЭС) и другими. Выявлены отклонения сердечно-сосудистой и нервной систем, высокая частота коморбидных заболеваний. Мальчики в большей степени имеют избыток As, Cd, Tl, а девочки – избыток Pb. Содержание в волосах испытуемых из г. Карабаша As и Pb выше по сравнению не только с показателями детей из других населенных пунктов, но и с рекомендуемыми среднероссийскими значениями.
ВЛИЯНИЕ ГЛУТАТИОН-СОДЕРЖАЩИХ ДИНИТРОЗИЛЬНЫХ КОМПЛЕКСОВ ЖЕЛЕЗА НА ОКИСЛИТЕЛЬНЫЙ МЕТАБОЛИЗМ КРОВИ КРЫС
Authors:   Приволжский исследовательский медицинский университет, Мартусевич А.К. , Соловьева А.Г. ,   Приволжский исследовательский медицинский университет, Ковалева Л.К. ,   Приволжский исследовательский медицинский университет
Published: July 2021

Изучали влияние динитрозильных комплексов железа (ДНКЖ) с глутатионовыми лигандами на параметры окислительного метаболизма крови крыс. Сопоставляли интенсивность липопероксидации, антиоксидантную активность и уровень малонового диальдегида в плазме крови крыс, получавших курс внутрибрюшинных инъекций физиологического раствора и раствора ДНКЖ (0,15; 0,30; 0,45 и 0,60 мМ). Показано наличие у ДНКЖ антиоксидантного эффекта, причем его выраженность демонстрирует нелинейную зависимость от их дозы с оптимумом в диапазоне 0,3–0,45 мМ.
Tratamento Farmacológico da Síndrome de Abstinência Alcoólica
Authors: Teixeira Joana
Published: July 2021

Introdução: Quando os consumidores excessivos crónicos de álcool, particularmente os indivíduos com o diagnóstico de perturbação de uso de álcool, suspendem abruptamente o consumo de bebidas alcoólicas, pode surgir um quadro clínico denominado síndrome de abstinência alcoólica. Nestes casos, é necessário muitas vezes instituir tratamento farmacológico para aliviar os sintomas e prevenir as complicações da abstinência. O tratamento farmacológico da síndrome de abstinência alcoólica é utilizado em unidades especializadas no tratamento de perturbação de uso de álcool, mas também pode ser necessário em serviços médico-cirúrgicos, quando esta síndrome se manifesta em doentes com perturbação de uso de álcool internados por patologias orgânicas.Métodos: Revisão de guidelines disponíveis na literatura sobre tratamento da síndrome de abstinência alcoólica com o objetivo de determinar qual o tratamento farmacológico recomendado.Resultados: Foram analisadas as quatro guidelines sobre tratamento farmacológico da síndrome de abstinência alcoólica (National Institute for Health and Care Excellence, American Society of Addiction Medicine, World Federation of Societies of Biological Psychiatry e American Psychiatric Association), em relação às suas recomendações e evidência da eficácia dos fármacos para tratamento da síndrome de abstinência alcoólica. Esta análise foi ainda complementada pela consulta das guidelines de Maudsley.Discussão: As guidelines analisadas recomendam, como tratamento de primeira linha, o uso de benzodiazepinas. A associação de anticonvulsivantes, agonistas adrenérgicos alfa-2, betabloqueantes e antipsicóticos com benzodiazepinas está recomendada para controlo sintomático em quadros de privação mais exuberantes. É recomendado administrar tiamina para profilaxia da encefalopatia de Wernicke-Korsakoff a todos os doentes. Caso existam desequilíbrios hidroelectrolíticos, estes deverão ser corrigidos.Conclusão: É fundamental manter um nível elevado de suspeita para o eventual aparecimento da síndrome de abstinência alcoólica em todos os contextos clínicos. Nesses casos, importa saber intervir precocemente.