bluuebunny/crossref_metadata_2025 huggingface dataset:
POKAZATELI METABOLIZMA I IMMUNNYY STATUS U DETEY S RAZLIChNYMI SOSTOYaNIYaMI GLOTOChNOY MINDALINY
Authors: Ponomareva Lyudmila Ivanovna , Alekseeva Yu A , Vinogradov A F
Published: June 2024

Children's health formation substantially depends on the status of the lymphoepithelial pharyngeal ring, the components of which are constituents of the uniform immune system, by developing the body's immunological resistance. The study used a number of metabolic and immunological parameters to assess a risk for a decreased health status in 210 children (115 boys and 95 girls) aged 4 to 10 years with various conditions of the pharyngeal tonsil. The increased and high levels of a skin automicroflora (SAMF) test were noted in children at risk for the development of chronic adenoiditis, which is suggestive of a diminished systemic immunological responsiveness. The levels of calcium and magnesium in the expired air condensate and the SAMF test may be used as markers of a decreased health status in children with pharyngeal tonsil pathology and as an additional risk factor for development of chronic adenoiditis.
Osobennosti deyatel'nosti i normativnaya baza dnevnogo statsionara
Authors: Kalininskaya Aleftina Aleksandrovna , Dzugaev A K , Stukalov A F , Guseva S L
Published: June 2024

The paper describes an organizational model of a day hospital (DH) that operates as a structural subdivision on the basis of a therapeutic-and-prophylactic institution. The authors present the structure of DH and its provision with medical staff. The paper analyzes these issues by age, gender, and reasons for patients' hospitalization to DH, provides a comparative analysis of medium-term stay at DH and round-the-clock hospital, and gives the results of treatment. Particular emphasis is placed on a physician's work quota setting and a load on a DH physician has been calculated.
Use of air-plasma flow during high amputations in patients with obliterating diseases of lower limb arteries
Authors: Shulutko A M , Osmanov Emkhan Gadzhikhanovich , Skopintsev V B , Antropova N V , Dzhamalov D M , Shulutko A M , Osmanov E G , Skopintsev V B , Antropova N V , Dzhamalov D M
Published: June 2024

The authors analyze the results of treatment in 249 patients with obliterating diseases of lower limb arteries, who underwent hip or upper-third leg amputation due to progressive humid gangrene in 2006 to 2009. In the study group (n = 112), low-power air-plasma flow (APF) was used in various modes at surgery. The Plazon apparatus is a source of plasma power. APF in the cut-coagulation mode was employed in all the patients during major surgical techniques (division of muscle masses and fascia, coagulation of minor vessels, treatment of nerve trunks). Before stump formation, an operation wound was additionally treated with cooled APF in NO-therapy mode. Comparison with a control group (n = 137) that had undergone traditional amputations revealed a significant reduction in the volume of intraoperative blood loss, the incidence of wound complications by 1.8 times, accelerated relief of fever and postoperative pain syndrome, and some clinical improvement, including the length of hospital stay.
Issledovanie toksichnosti i allergiziruyushchikh svoystv sbora dlya lecheniya pielonefrita
Authors: Krendal' Feliks Petrovich , Pronchenko G E , Rendyuk T D
Published: June 2024

The paper gives data of a study of the toxicity of herbal species for the treatment of pyelonephritis.
Lokal'naya gipotermiya v kompleksnom lechenii ostrogo destruktivnogo pankreatita
Authors: Korol'kov Aleksandr Yur'evich , Klimov A E , Morozova A B
Published: June 2024

The authors have developed a fundamentally new design of a pancreatic hypothermia device.
In 2007-2008, a drain was inserted for local hypothermia in 32 patients with pancreonecrosis.
The results of blood biochemical tests and pancreatic ultrasound studies are analyzed in these patients. These results are compared with data on patients undergoing laparoscopy or laparotomy without setting a drain for local hypothermia. It is concluded that local hypothermia is a rather effective technique and may be used in multimodality treatment for acute destructive pancreatitis.
Efectos del ejercicio aeróbico sobre los componentes del síndrome metabólico en adultos mayores con diabetes mellitus tipo 2: revisión sistemática y metaanálisis
Authors: Miranda-Tueros Mercedes , Ramirez-Peña Joshua , Cabanillas-Lazo Miguel , Paz-Ibarra José Luis , Pinedo-Torres Isabel
Published: June 2024

Objectives. To determine the effects of aerobic exercise on the components of the metabolic syndrome in older diabetic patients. Materials and methods: We used the PubMed/Medline, Scopus, Cochrane library, Web of Science databases and the Google Scholar search engine. Randomized controlled trials ( RCTs ) were selected according to the inclusion criteria. Two review authors independently determined whether studies met the inclusion criteria, extracted data and used the Cochrane risk of bias (ROB 2.0) tool. Quantitative analyzes were performed in R V. 4.0.5 using random effects. Results. The searches identified 8697 studies, of which 7 RCTs were included in the qualitative synthesis. Most studies were assessed to have high or low ROB in at least three domains. The meta-analysis showed that aerobic exercise was effective in improving glucose levels (standardized mean difference [SMD]: -1.04; 95% confidence interval [CI]: -1.27, -0.81), systolic blood pressure ([SMD]: -0.79; [CI]: -1.02; -0.56), diastolic blood pressure ([SMD]: -0.75; [CI]: -0.98; -0.52), glycosylated hemoglobin ([SMD]: -0.57, [CI]: -0.77, -0.37), HDL ([SMD]:0.35, [CI]: 0,15 ; 0.55), triglycerides ([SMD]: -0.26; [CI]: -0.47; -0.06). No significant adverse effects were  reported. Conclusions. Aerobic exercise was shown to have a significant improvement in the components of the metabolic syndrome in diabetic older adults and no significant adverse effects were reported. However, we recommend more RCTs with a longer intervention time to establish the impact on symptoms and complications.
Budget impact of upadacitinib in patients with moderate to severe rheumatoid arthritis in Argentina
Authors: Espínola Natalia , Secco Anastasia , Balan Dario , Kanevsky Diego , Calvi Guido , Morisset Pierre , Bardach Ariel , Augustovski Federico
Published: June 2024

Objetivos. Analizar el impacto presupuestario de upadacitinib (UPA) 15 mg + metotrexato (MTX) para el tratamiento de la artritis reumatoide (AR) moderada a  grave en pacientes con respuesta inadecuada a los fármacos antirreumáticos modificadores de la enfermedad convencionales (RI-DMARc) desde la  perspectiva de la seguridad social y los sectores de  salud privados en Argentina. Materiales y métodos. Se  desarrolló un modelo de análisis de impacto  presupuestario para una cohorte hipotética de 100,000  adultos con cobertura de seguro de salud que fueron  diagnosticados con AR en un horizonte de tiempo de 5  años. Los parámetros del modelo se obtuvieron a través de una revisión de la literatura y se validaron con expertos locales. Los costos se expresan en dólares  estadounidenses (USD) para el 2024. Resultados. La  introducción de UPA 15 mg + MTX para el tratamiento  de AR moderada a grave y RI-DMARc resultó en un costo incremental mínimo, con un costo acumulado total a cinco años de USD 1.855 para la seguridad social y USD 1.812 para el sector privado de salud, lo que representa aproximadamente el 2% del presupuesto total. El costo de adquisición de UPA fue la variable más influyente en  el análisis de sensibilidad. Conclusiones. La introducción de UPA 15 mg + MTX para el tratamiento de AR genera un incremento de costos marginal para el sistema de salud en Argentina, lo cual es especialmente importante en contextos de presupuestos limitados. Proporcionar estimaciones basadas en la evidencia es una herramienta valiosa para ayudar a tomar decisiones informadas sobre la asignación eficiente de recursos en salud.
Genes resistentes a carbapenémicos y colistina aislados en Musca domestica proveniente de un basural cercano a un hospital de Lima
Authors: Alarcón-Calle Miguel A. , Osorio-Guevara Víctor L. , Salas-Asencios Ramsés , Yareta José , Marcos-Carbajal Pool , Rodrigo-Rojas María E.
Published: June 2024

The objective was to determine the presence of genes resistant to carbapenems and plasmid resistance to colistin (mcr-1) in bacteria isolated from Musca domestica in a garbage dump near a hospital in Lima-Peru. Isolation of carbapenemase-producing bacteria was performed in CHROMagar mSuperCARBATM medium and colistin resistance profiling was performed by colistin discs elution method. Detection of blaKPC, blaNDM, blaIMP, blaOXA-48, blaVIM y mcr-1 genes was performed by conventional PCR. Antimicrobial susceptibility profile assessment was performed on the MicroScan automated system. Carbapenemase-producing bacteria were 31/38 and bacteria that were  resistant to colistin were 26/38 with an MIC ≥ 4 μg/mL. Finally, 7 bacterial strains with carbapenem resistance genes (OXA-48 and KPC) and one bacterial strain with plasmid resistance to colistin (mcr-1) were identified.
Adaptación y análisis psicométrico del cuestionario de ansiedad generalizada (GAD-7) al Quechua Collao en Perú
Authors: Cjuno Julio , Villegas-Mejía Raúl Alexis , Coronado-Fernández Jovita
Published: June 2024

Objetivos. Adaptar del inglés al contexto cultural y lingüístico del Quechua Collao y analizar las propiedades psicométricas del Cuestionario de Ansiedad Generalizada de 7 ítems (GAD-7) en Puno, Perú. Material y métodos. El GAD-7 en su versión original fue traducido a la variedad del quechua Collao y se analizaron sus propiedades psicométricas, los participantes fueron bilingües (español y quechua) mayores de 18 años y de ambos sexos. Se evaluó el  análisis factorial exploratorio (AFE) empleando el análisis paralelo, el análisis factorial confirmatorio (AFC)  y los índices de bondad de ajuste; asimismo se analizó la fiabilidad mediante el alfa clásico y Omega de Mc  Donald. Resultados. Los jueces y participantes del grupo focal realizaron la adaptación cultural y lingüística del GAD-7 al Quechua Collao; el AFE reportó la presencia de un único factor (KMO=0,88, p=0,01); mientras que el AFC confirmó adecuados ajustes en el modelo unifactorial (CFI=0,994; TLI=0,991; SRMR=0,027; RMSEA=0,092), una buena confiabilidad (α=0,896; ω=0,894) y además fue invariante en grupos de edad, sexo, estado civil y grado de instrucción. Conclusiones. El cuestionario presentó validez para un modelo unidimensional del GAD-7 adaptado al Quechua Collao, así como una óptima confiabilidad e invarianza por los grupos evaluados. Su uso podría beneficiar la investigación y atención de la ansiedad.
Detection of SARS-CoV-2 variants in hospital wastewater in Peru, 2022
Authors: Marcos-Carbajal Pool , Yareta-Yareta José , Otiniano-Trujillo Miguel , Galarza- Pérez Marco , Espinoza-Culupu Abraham , Ramirez-Melgar Jorge L. , Chambi-Quispe Mario , Luque-Chipana Néstor Alejandro , Gutiérrez Ajalcriña Rosmery , Sucñer Cruz Víctor , López Chegne Segundo Nicolas , Santillán Ruiz Diana , Segura Chavez Luis Felipe , Sias Garay Cinthia Esther , Salazar Granara Alberto , Tsukayama Cisneros Pablo , Tapia Paniagua Silvana Teresa , González-Domenech Carmen María
Published: June 2024

Objetive. To identify the presence of the SARS-CoV-2 virus in wastewater from hospitals in Peru. Materials and methods. Water samples were collected from the effluents of nine hospitals in Peru during March and September 2022. SARS-CoV-2 was identified by using Illumina sequencing. Variant, lineage and clade assignments were carried out using the Illumina and Nextclado tools. We verified whether the SARS-CoV-2 variants obtained from wastewater were similar to those reported by the National Institute of Health of Peru from patients during the same period and region. Results. Eighteen of the 20 hospital wastewater samples (90%) provided sequences of sufficient quality to be classified as the Omicron variant according to the WHO classification. Among them, six (30%) were assigned by Nextclade to clades 21K lineage BA.1.1 (n=1), 21L lineage BA.2 (n=2), and 22B lineages BA.5.1 (n=2) and BA .5.5 (n=1). Conclusions. SARS-CoV-2 variants were found in hospital wastewater samples and were similar to those reported by the surveillance system in patients during the same weeks and geographic areas. Wastewater monitoring could provide information on the environmental and temporal variation of viruses such as SARS-CoV-2.
Consenso internacional sobre nomenclatura en equinococosis: traducción y adaptación al español
Authors: Naidich Ariel , Elissondo María Celina , Vizcaychipi Katherina , Sienra Guzman , Ali Viterman , Gavidia Cesar M. , Guisantes Jorge
Published: June 2024

Echinococcosis has been known since the time of Hippocrates. Since then, terms and definitions have been coined or adapted in different languages to refer to multiple aspects related to this zoonosis. It is important to promote a good understanding in reading and writing at the level of scientific, academic information, for general knowledge and mass dissemination. During the 27th World Echinococcosis Congress, a working group was established for this purpose. The result was a consensus with  recommendations applicable to science and communication between professionals, published in 2020 in English. On the recommendation of some members of the WHO Informal Working Group on Echinococcosis (WHO-IWGE), a working group composed of experts on echinococcosis from Argentina, Bolivia, Chile, Spain, Paraguay, Peru and Uruguay was convened to prepare a proposal of terminology in Spanish. The result of this consensus is to propose a unified nomenclature of progressive application, which serves as a basis for consultation and reference.
Enhancing Salient Object Detection with Supervised Learning and Multi-prior Integration
Authors: Dhara Gayathri , Kumar Ravi Kant
Published: June 2024

Salient Object Detection (SOD) can mimic the human vision system by using algorithms that simulate the way how the eye detects and processes visual information. It focuses mainly on the visually distinctive parts of an image, similar to how the human brain processes visual information. The approach proposed in this study is an ensemble approach that incorporates classification algorithm, foreground connectivity and prior calculations. It involves a series of preprocessing, feature generation, selection, training, and prediction using random forest to identify and extract salient objects in an image as a first step. Next, an object proposals map is created for the foreground object. Subsequently, a fusion map is generated using boundary, global, and local contrast priors. In the feature generation step, different edge filters are implemented as the saliency score at edges will be high; additionally, with the use of Gabor’s filter the texture-based features are calculated. The Boruta feature selection algorithm is then used to identify the most appropriate and discriminative features, which helps to reduce the computational time required for feature selection. Ultimately, the initial map obtained from the random forest, along with the fusion saliency maps based on foreground connectivity and prior calculations, is merged to produce a saliency map. This map is then refined using post-processing techniques to acquire the final saliency map. The approach we propose surpasses the performance of 17 cutting-edge techniques across three benchmark datasets, showcasing superior results in terms of precision, recall, and f-measure. The proposed method performs well even on the DUT-OMRON dataset, known for its multiple salient objects and complex backgrounds, achieving a Mean Absolute Error (MAE) value of 0.113. The method also demonstrates high recall values (0.862, 0.923, 0.849 for ECSSD, MSRA-B and DUT-OMRON datasets, respectively) across all datasets, further establishing its suitability for salient object detection.
Teleorthodontics: Navigating skepticism and uncertainity
Authors: Wadhawan Richa , Kumar Shubham , Mathur Shivangi , Soni Stuti , Santosh Gandla Karthik , Parambil Anshif Thavalam , Parihar Shubham , Chacko Amal
Published: June 2024

Teleorthodontics, a subset of teledentistry, involves the use of digital communication technologies to provide remote orthodontic care. This approach enables orthodontists to diagnose, monitor and manage patients’ treatment without the need of in person visits. The concept has garnered traction due to advancements in telecommunication technologies, increasing accessibility to smart phones, and the need for remote healthcare services. Despite skepticism, there are several advantages of including tele- orthodontics in the clinical orthodontic practice. This article reviews the strength and weaknesses of this emerging healthcare communication system and its impact on orthodontics, which is set to transform the future of our clinical practice.
Evaluation of mechanical properties of nanoparticle-coated orthodontic brackets and wires
Authors: Swaroop M V Kirthi Sanjay , S M Laxmikanth , Talwar Ashita , M Sameena Begum , Riyaz Khadeer , Raghavendra S R
Published: June 2024

Any reduction in friction between the orthodontic wire and the bracket can speed up tooth movement in the sliding technique and result in improved 3-D control. The purpose of this study was to investigate frictional forces caused by covering orthodontic wires and brackets with silver oxide nanoparticles (AgO).

: In this study, 30 brackets (0.022 × 0.028” slot) and 30 arch wires (0.019 × 0.025” SS wires) were taken and split into 3 groups. The first group included uncoated arch wires and brackets. The second group included uncoated arch wires and coated brackets. The third group included coated arch wires and coated brackets. These brackets were further examined under Scanning electron microscopy to evaluate the AgO nanoparticle coating and its thickness. These brackets and wires were then subjected to a friction test with the help of a UNIVERSAL TESTING MACHINE. Frictional forces were statistically analysed using One-way ANOVA test followed by Tukey’s HSD Post hoc Analysis.

: Coating with AgO nanoparticles significantly influenced frictional force values (P < 0.0001). The first group showed 0.8690 ± 0.1512 N (control).

The second group showed 0.4815 ± 0.0840 N. The third group showed 0.2010 ± 0.0445 N. This mean difference in the Frictional force between 3 groups was statistically significant.

: AgO nanoparticles may be a unique way to dramatically reduce friction during tooth movement because of their beneficial impacts on lowering frictional forces.
Understanding, acceptance and compliance of patients towards orthodontic treatment: Questionnaire survey on ongoing cases
Authors: Bhutada Payal Brijlal , Maroore Pravinkumar , Kangane Suresh , Nakhate Trupti Shankar , Nair Swathilekshmi
Published: June 2024

To assess the understanding, acceptance and compliance of patient undergoing fixed orthodontic treatment.

A self-designed closed-ended questionnaire of 15 questions, addressing understanding, acceptance and compliance of patient were distributed to 400 adult patients undergoing fixed orthodontic treatment at MIDSR Dental College, India. Cross-sectional questionnaire survey was conducted. Before participation in the study consent was taken from every patient. The descriptive statistics was used for evaluation of obtained data.

A total of 400 participants responded to the survey. The results shows that patient’s understanding about necessity of treatment, its duration, and treatment plan for fixed orthodontic treatment was 62.2%. The acceptance rate for treatment selection by orthodontist, for wearing retainer and to convince friends or relatives for fixed orthodontic treatment was 53.52% and theywere happy with the treatment. While 69.5% patients were having good compliance for brushing teeth twice daily by using orthodontic toothbrush, for using mouthwash and for modifying diet with the fixed orthodontic treatment.

Although many of patients were found to have good understanding of orthodontic therapy but acceptance towards orthodontic treatment and orthodontic treatment protocols was average. Orthodontist still need to work on this aspect to increase the acceptance of treatment among patients. The Compliance of patients was satisfactory as they strictly adhere to dietary restrictions maintained good oral hygiene by using special cleaning aids. The study concludes that the orthodontists need to take an active role in increasing orthodontics-related patient behaviours by improving patient education
Rapid maxillary expansion appliance in correction of unilateral skeletal crossbite in an adult female patient: A case review
Authors: Kumar Sanjay , Kedia Neel Bharat
Published: June 2024

The case was treated with bonded rapid palatal appliance successfully in adult female from Nepal. The occlusion and her smile have improved satisfactorily. The other associated sign and symptoms such as recurrent rhinitis and breathing problem also improves after this treatment. Few clinical problems that arose during the treatment were successfully addressed as well. At the end of the treatment, patient was very happy and satisfied. Though her age was not in favour of application of RME treatment, but careful examination of diagnostic aids helped us in arriving at correct treatment planning and her treatment with RME.
Anterior open bite correction in adults through MEAW technique: A case report
Authors: Nazeer Anfiya , Paul Sam , Chacko Prince , Peter Varun
Published: June 2024

Anterior open bite malocclusion presents a challenging issue in orthodontic treatment. This difficulty arises from the distinct occlusal planes of the maxillary and mandibular dentitions. Unlike the overlap observed in normal occlusion, the open bite is characterized by the anterior divergence of these planes. This is a case report of a 25-year-old female patient with an anterior open bite successfully treated with the MEAW technique. There is an overall improvement in the patient's facial profile and occlusion post-treatment.
A inclusão da pessoa com deficiência através de concurso público: análise dos concursos realizados pelo Tribunal de Justiça da Paraíba nos anos de 2008 e 2012
Authors: De Paiva Medeiros de Oliveira Flávia , Forte de Negreiros Deodato Felipe Augusto , Yamaoka Mariz Maia Pitanga Lua
Published: June 2024

O presente artigo tem, por finalidade, a análise dos critérios para ascensão na carreira profissional dos aprovados nas vagas reservadas para deficientes nos últimos concursos públicos para servidores do Tribunal de Justiça da Paraíba, realizados em 2008 e 2012, e a progressão funcional em igualdade de oportunidades. Considerando as ações afirmativas, examina-se a política de reserva de quotas para deficientes em concurso públicos e a imposição constitucional como instrumento de inclusão, de acordo com os princípios da igualdade e da dignidade da pessoa humana, previstos na Constituição Federal de 1988, na Convenção Internacional sobre Direitos da Pessoa com Deficiência e Estatuto da Pessoa com Deficiência. Através de pesquisa bibliográfica, e análise documental e exploratória, levantaram-se dados dos últimos concursos (2008 e 2012), para analisar os critérios adotados nos respectivos editais, a lotação e a promoção na carreira laborativa dos servidores deficientes, examinando a articulação da proteção jurídica das pessoas com deficiência com o princípio geral de igualdade. Nesse contexto, verifica-se que as ações afirmativas direcionadas à pessoa com deficiência vem se consolidando ao longo do tempo, haja vista que muitas conquistas foram alcançadas, mas resta comprovada que a concretização dessas  medidas está ligada à compreensão de seus destinatários e dos superiores imediatos, responsáveis por avaliá-los e por promover um ambiente de trabalho produtivo e adaptado às deficiências apresentadas pelo subordinado. Assim, firma-se a necessidade imperiosa de uma cultura que respeite as diferenças, como baluarte do valor maior da dignidade da pessoa humana, meta perene da Constituição de 1988.
Avaliação da Funcionalidade de Pacientes Amputados: Comparação Entre os Níveis Transfemoral e Transtibial
Authors: Lize Sayuri , Weber Letícia , Bonetti Leandro Viçosa , Saccani Raquel
Published: June 2024

Objetivo: O objetivo deste estudo foi avaliar a funcionalidade de pacientes amputados analisando as diferenças entre os níveis transtibial e transfemoral e a interferência da idade. Métodos: Trata-se de um estudo observacional, analítico, de caráter comparativo e abordagem transversal, com amostra de 24 indivíduos adultos e idosos de ambos os sexos, sendo seis amputados do nível transtibial e 18 amputados do nível transfemoral unilaterais. Foram utilizados os seguintes instrumentos: questionário de identificação criado pelas pesquisadoras para caracterização da amostra, Amputee Mobility Predictor (AMP), Medida de Independência Funcional (MIF), Timed up and Go (TUG) e o Índice de Capacidade Locomotora (LCI). Foi utilizada estatística descritiva, teste t independente e o teste de Correlação de Pearson.  O nível de significância adotado foi p? 0,05 Resultados: O grupo transtibial apresentou melhor nível funcional do que o grupo transfemoral, sendo significativo para o instrumento AMP (p= 0,03). Além disso, verificou-se que quanto maior a idade, menor a funcionalidade dos pacientes. Conclusões: Este estudo constatou que o nível da amputação interfere na funcionalidade, assim como a idade. Ainda, a AMP foi o melhor preditor para o resultado da mobilidade.
Concurrence des sanctions répressives dans la fonction publique: réflexions sur son admissibilité et ses limites
Authors: Trochez Fernández Carlos
Published: June 2024

La iniciación simultánea de actuaciones disciplinarias y penales contra servidores públicos y la incidencia del principio non bis in idem sobre esta concurrencia se revela como un tema de discusión permanente desde la consolidación del derecho disciplinario como subsistema jurídico autóno­mo. La aprehensión de dicho principio en la doctrina publicista y penal, así como en la jurisprudencia, tanto en Francia como en Colombia, se inscribe en una inadmisibilidad unánime, lo cual deja espacio a la aplicación original de otros principios con el objetivo de aminorar la gravedad de la concurren­cia de sanciones disciplinarias y penales. El presente artículo constituye un estudio de derecho comparado entre los ordenamientos jurídicos de Francia y Colombia, que pone de relieve los principales retos de la acumulación de actuaciones y ofrece elementos de reflexión para reforzar las garantías de los procesos punitivos contra servidores públicos.
¿Cómo probar la culpabilidad para exigir responsabilidades a los servidores públicos?
Authors: Rivero Ortega Ricardo
Published: June 2024

La exigencia de responsabilidades a los servidores públicos debería respetar las garantías propias del Estado de derecho. Contra la manipulación política de los procesos y también frente a la impunidad, una correcta aplicación de las reglas probatorias favorecería la seguridad jurídica y la confianza en la rendición de cuentas. El presente artículo examina cómo la prueba de cono­cimiento del carácter ilícito de las conductas de servidores públicos puede lograrse a través advertencias desatendidas, señales de alarma insertas en los procedimientos administrativos.
La transparencia como instrumento de control ciudadano sobre las funciones administrativas ejercidas por particulares en Cataluña
Authors: González-Juliana Álvaro
Published: June 2024

El artículo estudia la aplicación de la ley catalana de transparencia, acce­so a la información pública y buen gobierno a las entidades privadas que ejercen funciones públicas o potestades administrativas, prestan servicios públicos o perciben fondos públicos para funcionar o para llevar a cabo sus actividades por cualquier título jurídico. Se analiza la obligación que tienen estas entidades de suministrar a la administración responsable la información directamente relacionada con la actividad pública que desarrollan a la luz de la doctrina emanada por la Comisión de Garantía del Derecho de Acceso a la Información Pública de Cataluña (GAIP).
Las relaciones entre la nulidad y prescripción en la potestad sancionadora
Authors: Méndez Vásquez Diego Enrique
Published: June 2024

Este trabajo analiza los posibles escenarios y relaciones que pueden ocurrir cuando la prescripción y nulidad se presentan, casi de manera conjunta, en el ejercicio de la potestad sancionadora de la Administración pública. En concreto, se estudia la prescripción como límite para la validez de la san­ción administrativa, como consecuencia de la invalidez del procedimiento sancionador, y, su impacto en la validez de la fiscalización administrativa.
Delimitación competencial de las regiones administrativas y de planificación en Colombia. Especial énfasis en la región central o RAP-E
Authors: Sanjuanelo Ortiz José Rafael
Published: June 2024

El presente escrito aborda las competencias de las regiones administrativas y de planificación o RAP, que son creadas por los departamentos y también por el Distrito Capital. Particularmente, se persigue determinar cuál es el límite que tienen las aludidas entidades territoriales para establecer las fun­ciones que les corresponde a las RAP. Asimismo, el artículo revisa el aporte que en materia de descentralización territorial se da con la creación de las regiones administrativas y de planificación, teniendo en cuenta que el margen que tienen las entidades territoriales para definir sus competencias suele ser asociado a un mayor nivel de descentralización.
Relational social capital and women entrepreneurs’ performance: The role of women entrepreneurs' satisfaction and innovation mindset
Authors: Bchini Belgacem
Published: June 2024

This research aims to study the impact of relational social capital on the performance of women entrepreneurs, taking into account innovation mindset as a mediating variable and women's satisfaction as a moderating variable. After interviewing 260 Tunisian women entrepreneurs, the researcher was able to validate the hypotheses using the MACRO PROCESS. Our findings can be summarized as follows: relational social capital has a positive and significant effect on women entrepreneurs' performance and innovation mindset. In turn, innovation mindset has a positive and significant effect on the performance of women entrepreneurs. The direct effect and the indirect effect of social capital on innovation mindset are moderated by women entrepreneurs' satisfaction. After discussing the results found, this research concludes with a presentation of the implications, both theoretical and managerial.
Keywords: Entrepreneurship; innovation mindset; women; relational social capital.
Enfoque diferencial: otros caminos pedagógicos para fortalecer la educación contable desde aproximaciones a la interculturalidad
Authors: Gómez Fajardo Rosa Mercedes , López Alegría Fabián Alfonso , Comunidad Indígena de Puracé
Published: June 2024

Este documento se constituye en una reflexión acerca del enfoque diferencial y la interculturalidad como herramientas que posibiliten el encuentro de otros caminos pedagógicos para fortalecer la educación contable. Metodológicamente, es un trabajo de carácter descriptivo-participativo, por el cual las comunidades son actores estratégicos de este proceso. Es una apuesta que lleva a abordajes desde el acercamiento a los territorios y el entretejido de saberes con comunidades rurales, a fin de comprender lógicas económicas otras y contribuir en alguna medida al fortalecimiento organizativo y al desarrollo local. Se evidencia desde esta propuesta que es posible trascender barreras, con miras a fomentar hilares epistémicos, entre las comunidades y la academia, que posibilitan la configuración de dinámicas de fortalecimiento identitario y del ejercicio de su autonomía, así como el enriquecimiento de la disciplina contable.
Articulación y planeación: lineamientos de gestión para el Observatorio de los ODS de Antioquia
Authors: Ceballos Betancur Wilfer Arley , Suescún Espinal Juan Felipe , Ocampo Suárez Héctor Mario , Gómez Jaramillo Sebastián , Vásquez Echavarría Gladis Helena , Reyes Gamboa Adriana , Torres Ramírez Juan José
Published: June 2024

En este trabajo se analizan y caracterizan los supuestos, lineamientos y lógicas institucionales en materia de programas sociales, que reflejan diferentes modelos de desarrollo en Argentina, a través de dos gobiernos consecutivos. Para ello, se concentra en “Argentina Trabaja” - Programa de Ingreso Social con Trabajo (AT-PRIST), creado en la gestión del Frente para la Victoria y que experimentó modificaciones con el gobierno de la Alianza Cambiemos, hasta transformarse en “Hacemos Futuro”. Estos programas se enmarcan en modelos de desarrollo que muestran la tendencia del abordaje de la cuestión social entre el 2009 y el 2018, pasando del modelo de inclusión social al modelo ceocrático en el neoliberalismo tardío. La metodología aplicada en este estudio es cualitativa y tiene una perspectiva diacrónica. El corpus teórico ha sido conformado por normativas, documentos oficiales, peticiones de información al MDSN, observación participante y entrevistas semiestructuradas.
Sostenibilidad sociocultural del turismo en un territorio del Caribe colombiano: un estudio empírico
Authors: Vargas-Leira Freddy de Jesús , Nadal Tersa Jordi
Published: June 2024

Este artículo se elabora con el propósito de evaluar el grado de sostenibilidad, desde la perspectiva sociocultural, con el que se lleva a cabo la actividad turística en un territorio costero del Caribe colombiano, así como con el fin de comparar su comportamiento frente al de otros destinos turísticos. Se empleó el método de estudio de casos, con enfoque metodológico cualitativo, y con base en la aplicación de encuestas y consulta de fuentes secundarias se implementaron doce indicadores para evaluar la sostenibilidad sociocultural del turismo. Los hallazgos permitieron identificar similitudes en materia de igualdad de género y discrepancias significativas en cuanto a la penetración, accesibilidad y satisfacción de los residentes con el turismo. El trabajo concluyó identificando la necesidad de realizar estas mediciones de manera periódica por medio de una estrategia de seguimiento y monitoreo, lo que maximizaría su relevancia y fortalecería los procesos de planificación y gestión del turismo en el ámbito local.
Apoyo desde la universidad a emprendedores en zonas de posconflicto: estudio de caso
Authors: Barón Chivara Jesús Alexis , Cote Daza Sandra Patricia , Mora González Edison Javier , Garau Vadell Joan Baptista
Published: June 2024

Con la firma del Acuerdo de Paz en Colombia en el 2016, las oportunidades de emprendimiento en las zonas de posconflicto se incrementaron. Sin embargo, los emprendedores en estos lugares carecen de habilidades y conocimientos que puedan hacer que sus ideas de negocio sean competitivas. Se expone un modelo de beneficio mutuo entre la universidad y los emprendedores de ocho departamentos de Colombia como estudio de caso. La metodología utilizada fue la investigación acción participativa, y se realizó en tres etapas: diagnóstico, programación y evaluación. La importancia de la investigación radica en su aporte al conocimiento sobre el rol que pueden tener las universidades en el desarrollo de emprendimientos en zonas de posconflicto. En los resultados se evidencia el acompañamiento a 116 emprendimientos a necesidades específicas de diseño de marca, diseño de empaques y procesos turísticos, entre otros.
Children Discontinue Studies Due to Homelessness and Negligence, or Fall into Substance Abuse
Authors: programme CLARISSA
Published: June 2024

The CLARISSA Nepal Action Research Group discussed in this report is located in a UNESCO world heritage site, in one of the Durbar Squares in Kathmandu Valley. The location was selected as a cluster for CLARISSA processes due to its density of street-connected children and child street vendors. These children are highly mobile, and the nature of the neighbourhood is diverse. The involvement of children in child labour, such as children working in small-scale khaja ghars and Adult Entertainment Sector venues, can be directly seen in this area, making it an important location for CLARISSA Action Research. This Action Research Group focused on two topics: children discontinuing their studies due to homelessness and negligence, and children falling into substance abuse.
People-driven Solutions: An Introduction to Facilitating Deep Participation for Systemic Change Through Systemic Action Research Programming
Authors: Hillier Lucy
Published: June 2024

CLARISSA evidence builds upon an existing body of evidence (Burns, 2014; Howard et al., 2021) around deeply participatory processes, where children and adults are given significant decision-making power, and supported to collect data, analyse, and take action in order to shift system dynamics to improve their lives. Critical factors within a process of whole systems change are facilitating child- and people-driven evidence generation; participatory learning and action processes around underlying system dynamics and how they drive a problem; and a high level of collective ownership by participants. These critical factors can be enabled through a facilitation approach, inclusive participation, collective problem-solving, and by giving more decision-making power to children and adult stakeholders by considering them as agents of change. The purpose of this resource is to introduce development and humanitarian organisations and their teams to a programme approach and methodology which can enable deeply participatory, learning- and action-oriented, whole systems change. It is written with the understanding that while most development and humanitarian organisations and programmes are not set up to ‘do research’, this does not mean that they cannot start to use the principles of a Systemic Action Research approach to enhance their work. This resource can help demystify the perception that robust, participatory, child- and people-led Action Research is more difficult or not possible; only relevant for monitoring, evaluation and learning teams; or that the methods are too technical for most practitioners or local participants.
The Effect of the Life and Technology-Based Learning Model on Students' Environmental Perception
Authors: Boz Kömü Vildan , Görgülü Arı Asli
Published: June 2024

This study aims to measure the effects of teaching conducted with the Life and Technology-Based Ecology Learning Model on students' environmental perception. The research was conducted with 30 undergraduate science education
students who are enrolled in a state university faculty of education. A quasi-experimental design with a pretest-posttest control group, which is a quantitative research method, was used in the research. The "Environmental Perception Scale" developed by Çakmak (2020) was utilized as the data collection tool to find out whether there were significant differences between groups before and after the application for both the treatment and control groups. The implementation of the learning model lasted for 14 weeks. The research was carried out within the extent of the Sustainable Ecology course developed and proposed by the researchers. During the application process, life-and-technology-based experiments and applications are conducted with the treatment group students as well as the conventional teaching. The results of the study suggest that the post-test scores of the Environmental Perception Scale demonstrated a significant advantage for the treatment group. It was concluded that teaching conducted with the Life and Technology-Based Ecology Learning Model was more effective than traditional instruction regarding students' environmental perception acquisition. For future studies, it may be recommended to apply the Life and Technology-Based Ecology Learning Model to different age groups to investigate its effectiveness at various developmental stages.
Mucormicose rinocerebral: relato de caso em paciente imunocompetente
Authors: Souza Raquel Custódio , Muniz Camila Rêgo , Feitosa Priscilla  Mariana Freitas Aguiar , Hirth Carlos Eduardo , Silva Viviane Carvalho da , Nunes André Alencar Araripe
Published: June 2024

Apresentação do Caso: Masculino, 62 anos, agropecuarista, foi admitido com cefaleia frontal, pulsátil e diária. Tomografia de Crânio (TC) sugerindo sinusopatia esfenoidal inflamatória aguda associada a fungo. Realizado tratamento clínico em serviço de origem, não especificado, com melhora parcial. Retorno da cefaleia associada a diplopia e estrabismo convergente de olho esquerdo. Nova TC com formação expansiva sólida infiltrativa na base do crânio preenchendo esfenoide esquerdo com destruição da parede, obliterando recesso esfenoetmoidal ipsilateral e captação do contraste. Realizada cirurgia transesfenoidal, mediante hipótese de cordoma. Anatomopatológico: colonização fúngica, suspeita de mucormicose. Após investigação sorológica e de comorbidades, concluiu imunocompetência. Tratado com Anfotericina B e Micafugina. Segue em acompanhamento, sem sinais de recidiva da infecção. Discussão: A mucormicose rinocerebral é uma infecção fúngica invasiva, rara e grave. Apresenta-se com comprometimento de seios paranasais, comumente maxilar, raramente acometendo esfenoide, seio cavernoso, órbitas e cavidade craniana. Incomum nos imunocompetentes. Os sinais e sintomas são febre, edema periorbital ou facial, diminuição da acuidade visual, oftalmoplegia e cefaleia. Considerações finais: Mucormicose rinocerebral é incomum em indivíduos sem comprometimento imunológico. Entretanto, esse caso demonstra a necessidade de suspeição diagnóstica para detecção precoce e tratamento imediato devido à elevada mortalidade. A associação entre terapêutica cirúrgica e clínica é decisiva para o prognóstico.
Recent advanced lipid-based nanomedicines for overcoming cancer resistance
Authors: Dechbumroong Piroonrat , Hu Runjing , Keaswejjareansuk Wisawat , Namdee Katawut , Liang Xing-Jie
Published: June 2024

The increasing prevalence of cancer drug resistance not only critically limits the efficiency of traditional therapies but also causes relapses or recurrences of cancer. Consequently, there remains an urgent need to address the intricate landscape of drug resistance beyond traditional cancer therapies. Recently, nanotechnology has played an important role in the field of various drug delivery systems for the treatment of cancer, especially therapy-resistant cancer. Among advanced nanomedicine technologies, lipid-based nanomaterials have emerged as effective drug carriers for cancer treatment, significantly improving therapeutic effects. Due to their biocompatibility, simplicity of preparation, and potential for functionalization, lipid-based nanomaterials are considered powerful competitors for resistant cancer. In this review, an overview of lipid-based nanomaterials for addressing cancer resistance is discussed. We summarize the recent progress in overcoming drug resistance in cancer by these lipid-based nanomaterials, and highlight their potential in future applications to reverse cancer resistance.
Structural damage identification method based on Swin Transformer and continuous wavelet transform
Authors: Xin Jingzhou , Tao Guangjiong , Tang Qizhi , Zou Fei , Xiang Chenglong
Published: June 2024

The accuracy improvement of deep learning-based damage identification methods has always been pursued. To this end, this study proposes a novel damage identification method using Swin Transformer and continuous wavelet transform (CWT). Specifically, the original structural vibration data is first transferred to a time-frequency diagram by CWT, thereby capturing the characteristic information of structural damage. Secondly, the Swin Transformer is applied to learn the two-dimensional time-frequency diagram layer by layer and extract the damage information, by which the damage identification is achieved. Then, the identification accuracy of the proposed method is analyzed under various sample lengths and different levels of environmental noise to validate the robustness of this approach. Finally, the practicality of this method is verified through laboratory test. The results show the proposed method can effectively recognize the damage and achieve excellent accuracy even under noise interference. Its accuracy reaches 99.6% and 99.0% under single damage and multiple damage scenarios, respectively.
LAW AND ETHICAL PARADIGMS IN THE DISCOURSE ON WESTERN PHILOSOPHY AND ISLAMIC PHILOSOPHY
Authors: S Citra Widyasari , Mukarramah Mukarramah , Iskandar Iskandar , Nawangsari Rahma Pramudya
Published: June 2024

There are differences in the approach to law and ethics in Western philosophy compared to law and ethics in Islamic philosophy. Western philosophy itself is divided into several schools, including natural law philosophy, legal realism or positivistic philosophy, historical philosophy of law, sociological philosophy of law, and utilitarianism. These schools have different views on the position of law and ethics. In the discourse of Islamic philosophy, Law and Ethics or Morality are seen as interrelated principles. While Western philosophy is divided into several schools and dichotomizes between Law and Ethics, in Islamic philosophy they are integrated into the view that law and ethics are a unity and represent the spirit of Islamic teachings. This research aims to explain the role of law and ethics in Western philosophical schools. This research will explain how Western philosophical thought relates to law and ethics, and how the integration of law and ethics occurs in the context of Islamic philosophy. This research is a type of literature review or bibliographic study. The method applied in this research is descriptive analysis using a comparative approach. In the issue of Law and ethics, Western philosophical schools are divided into two views: those that unite law and those that separate law and ethics. The view that unites law and ethics includes natural law philosophy and historical philosophy of law. The view that separates law and ethics includes legal realism, positivism, social jurisprudence, and utilitarianism. Meanwhile, in the context of Islamic philosophy, the relationship between law and ethics is considered an integrated dimension in human life that cannot be separated.
Penilaian Tingkat Kesehatan BUMN Ditinjau dari Rasio Keuangan (Studi Pada PT Telkom Indonesia Tbk)
Authors: Zikri Illahi  , Anindya Khoirina Noor , Mellisa Fitri Andriyani Muzakir  , Tri Lestari Wahyuning Utami  , Arief Darmawan
Published: June 2024

Penelitian ini bertujuan untuk menilai tingkat kesehatan Badan Usaha Milik Negara (BUMN) berdasarkan pada Surat Keputusan Menteri BUMN Nomor: KEP-100/MBU/2002. Penelitian ini menggunakan pendekatan kualitatif deskriptif naratif dengan menggunakan data sekunder berupa laporan keuangan yang diterbitkan oleh PT Telkom Indonesia Tbk dalam kurun waktu 5 tahun (2017 – 2021). Terdapat 4 rasio keuangan utama yang digunakan yaitu profitabilitas, likuiditas, aktivitas dan solvabilitas. Untuk mengukur keempat variabel tersebut maka digunakan 8 proksi (indikator) yaitu Return on Equity (ROE), Return on Investment (ROI), Cash Ratio, Current Ratio, Collection Period, Perputaran Persediaan, Total Aset terhadap Total Aset Turnover (TATO), dan Total Modal Sendiri (TMS) terhadap Total Aset.  Rata-rata skor dari perhitungan 8 indikator tersebut adalah 89,14 dimana dalam kategori penilaian tingkat kesehatan adalah AA yang artinya perusahaan mendapatkan predikat “Sehat”.