bluuebunny/crossref_metadata_2025 huggingface dataset:
Specifying Soil Volumes to Meet the Water Needs of Mature Urban Street Trees and Trees in Containers
Authors: Lindsey Patricia , Bassuk Nina
Published: May 2022

The small volume of soil in a typical street tree pit or container often is not capable of supplying adequate water as the tree needs it. As a result, trees can experience severe limitations upon healthy growth and development. Current soil volume estimations fail to address three problems: 1) how to predict whole tree water use, especially for a wide range of prevailing climatic conditions, 2) now to tie this prediction to some easily measured tree parameter, and 3) how to incorporate both of the above into some simple yet accurate means of estimating soil volume. A weatherbased methodology for adequately sizing soil volumes is presented to address these concerns. This incorporates the findings of a recent study indicating that whole tree water loss can be reasonably predicted with knowledge of evaporation from a U.S. Weather Bureau Class A pan. A soil volume of 220 ft3 for a medium sized tree is then calculated. For use as a general estimate, 2ft3 of soil per 1ft2 of crown projection is recommended.
Nitrogen Fertilization of Hemlock Increases Susceptibility to Hemlock Woolly Adelgid
Authors: McClure Mark
Published: May 2022

Fertilizing eastern hemlock (Tsuga canadensis) with nitrogen stimulated population growth of the hemlock woolly adelgid (Adelges tsugae) in a forest plantation in Connecticut. Percent survival of nymphs and the number of eggs produced per adult of this adelgid were more than twice as high on fertilized hemlocks than on unfertilized ones. Fertilized hemlocks had five times more adelgids, had inferior color, and produced 25% less new growth than unfertilized trees after a single adelgid generation. These trends did not differ between hemlocks which had been fertilized 6 months prior to infestation by A. tsugae and those which were fertilized at the same time that trees were infested. Therefore nitrogen fertilization of hemlock neither increased host resistance to the adelgid nor repressed adelgid population growth following establishment. These results may be generally applicable to piercing and sucking insects which feed on trees and shrubs.
ИССЛЕДОВАНИЕ НАДЕЖНОСТИ ЦЕЛЬНОМЕТАЛЛИЧЕСКИХ ПОЛУВАГОНОВ
Authors: Р. Ю. Зарипов  , А. Д. Сулейменов  , Ж.Р. Каримова
Published: May 2022

Проведен анализ состояния инвентарного вагонного парка по построенным и списанным грузовым вагонам, а именно цельнометаллическим полувагонам. На основе статистических данных определено, что данный тип грузовых вагонов является самым многочисленным в составе инвентарного парка вагонов. Приведены результаты исследований показателей надежности для кузова полувагона с последующим анализом отказов по узлам и деталям, которые требуется усовершенствовать при проектировании вагона нового поколения для максимальной адаптации их к средствам механизации при погрузочно-разгрузочных работах. В качестве исходных данных для анализа параметров надежности приняты данные по распределению отказов в целом по несущей конструкции кузова При анализе надежности за основу взяли расчет безотказности, что оценивает работоспособность вагона с начального периода эксплуатации до первого деповского ремонта, или между отцепочными при условии полного восстановления неисправных или поврежденных узлов и деталей кузова вагона В ходе проведения исследований принят ряд рекомендаций, способствующих повышению надежности конструкции кузова полувагона. Для исследования надежности кузовов в целом и их частей, и элементов в частности, по полученным из эксплуатации материалам выведена и построена гистограмма параметра потока отказов от времени. Зависимость описывается по экспоненциальному закону и показывает снижение параметра потока отказов с ростом календарного срока использований после деповского ремонта.
DEVELOPMENT OF THE DESIGN OF A PEAKLESS ROTARY CUTTING TOOL
Authors: M. K. Ospantaev
Published: May 2022

Processing of external surfaces with turning tools is the most common in the total mass of tools, and occupies a special place in the technological process of manufacturing machine parts. The issues of increasing productivity, accuracy and reliability of the processing process have always been and remain relevant and effective for metalworking. The aim of the study is to improve the quality of processing of external cylindrical surfaces with the development of a new processing method and the design of a peakless turning through-hole cutter. The idea of the work is to develop a new design of a lathe cutter for finishing and a new processing method. The analysis of methods and methods of processing external cylindrical surfaces, parameters of the cut layer during cutting, geometry and designs of turning cutting tools, led to the development of a new metal-cutting tool - a peakless turning cutting tool for finishing. The new design improves cutting conditions and minimizes the impact of adverse factors accompanying the cutting process. Thus, a pass-through peakless cutter has one cutting edge, is simpler due to the absence of an auxiliary back surface and top, has less complexity of manufacturing and sharpening, and therefore requires less operating costs.
ТҮРЛІ КОНСТРУКЦИЯДАҒЫ СУМЕН САЛҚЫНДАТЫЛАТЫН ТЕСКІШ ҚҰРАЛБІЛІКТІН ҚАТТЫ КҮЙДЕГІ КОМПЬЮТЕРЛІК МОДЕЛЬДЕУДІ ТАЛДАУ
Authors: А.Ж. Касенов  , М.Ж. Тусупбекова  , Р.Б. Муканов
Published: May 2022

Конструкцияның тозуын азайту мақсатында сумен салқындатылатын тескіш құралбіліктердің қолданыста бар екі конструкциясының талдауы қарастырылады. «КОМПАС-3D» автоматтандырылған жобалау жүйесін қолдана отырып компьютерлік модель құрастырылды жән температуралық талдау жүргізілді. CAD/CAE/CAM кешендерінің құрамындағы CAE бағдарламаларын қолдану тәжірибесіне сүйене отырып және CAE жүйелерін машина жасаудағы әртүрлі зерттеу және жобалау мәселелерін шешуде есептеу эксперименттерін жүргізудің заманауи құралы ретінде орналастырып, негізінде APM FEM қолданбалы кітапханасын қолдану. Қобалау процесі жіксіз құбырларды өндірудегі негізгі процестердің бірі болып табылады, ал көлденең бұрандалы илемдеу орнақтарының жұмысында қолданылатын тескіш құралбілік, өндірілетін гильзаның сапасына айтарлықтай әсер етеді. тескіш құралбіліктің тұрақтылық мәселесі, барлық қобалаушы орнақтарға тән. Қобалаушы орнақтардың істен шығуы олардың қобалау кезіндегі жұмысының агрессивті жағдайларына байланысты (жоғары температура әсерінен деформация ошағында болуы), ал легирленген болаттан жасалған жіксіз құбырларды өндіру процесі илемдеу жағдайын едәуір нашарлатады. Compass-3D бағдарламасында тескіш құралбілік конструкциясының жобалаумен 3D модельдеу арқылы өндірістегі тескіш құралбілікке талдау жасалады, соның нәтижесінде қызмет жасау мерзімі артты.
Herstellung von nanostrukturierten Magnesiumlegierungen durch ECAP-Prozess
Authors: Ryspaev T.A.
Published: May 2022

Um die nanostrukturierte Magnesiumlegierungen zu entwickeln wurde der ECAP-Prozess gewählt, der zurzeit intensiv erforscht wird. Das Potential dieses Umformverfahrens wurde anhand der zwei Magnesiumlegierungen AZ91 und AE42 demonstriert. So wurden nach 8 ECAP-Durchgängen eine mittlere Korngröße von 2 µm und 0,45 µm jeweils in AE42 und AZ91 erzielt. Dieser Unterschied zwischen den Korngrößen in AE42 und AZ91 bestätigt noch einmal den Einfluss der Ausscheidungen auf die Korngröße, da der Aluminiumgehalt in AZ91 etwa zweimal höher ist als in AE42, was auch fast die Hälfte der Ausscheidungen Mg17Al12 in AE42 bedeutet. Zusammenfassend lässt sich sagen, dass die ECAP-Verformung der industriellen Magnesiumlegierungen AZ91 und AE42 zur Ausbildung einer feinkörnigen Mikrostruktur führt. Deutlich ist zu sehen, dass die mittlere Korngröße der Legierung AZ91 nach jedem verwendeten ECAP-Durchgang kleiner ist als der Legierung AE42. Diese Untersuchungen bestätigen, wie auch die Ergebnisse der Strangpressen und Rundkneten dieser beiden Legierungen, dass neben den Effekten der Kornfeinung beim ECAP-Prozess auch das Vorhandensein der Ausscheidungen der zweiten Phasen einen großen Einfluss auf die Kornstruktur- bzw. Korngröße hat. Da der Aluminiumgehalt in Legierung AE42 etwa halb so groß ist wie in AZ91, was etwa die Hälfte der Ausscheidungen der Mg17Al12 in AE42 bedeutet, ist die ultrafeinkörnige Mikrostruktur in AZ91 durch die bei gleichen Überalterungsund Strangpressentemperaturen von 300 °C ausgeschiedenen Partikeln der β-Phase zu verdanken.
Effectiveness of Memory Model in Terms of Long Term Memory of Class IX Students
Authors: Dr. Jasmeet Kaur Tandon  , Dr. Sarita Sharma
Published: May 2022

Memory is the ability to remember past experiences, previously learned facts, skills, habits etc. it helps to retrieve the stored information in our brain whenever we need that particular part of information for our current activity. Without memorization the life is impossible and it is a known fact that people with good memory are more successful people. Thus memory plays an important role in day to day life of an individual. As we know that memory is the most important and fundamental aspect of teaching learning process. In the teaching learning process, the learners have to remember the information, knowledge and wisdom gathered by self and others. There is a definite purpose through which all this is stored in the brain. Memory is the process by which information is encoded, stored and retrieved. In today’s scenario we see that our whole examination system is based on memorization of facts, skills, experience etc. thus there is a need to find the way/ technique to improve the memory system and help us to learn meaningful language. Memory model can be one of the model by which Short term Memory and Long term Memory can be enhanced. Memorization helps to train the mind to focus and help students and teachers to obtain pre determined goals confirmed by the behavioral action of students.
Interaction with Paintings by Augmented Reality and High Resolution Visualization. A Real Case Exhibition
Authors: Viplav Khode  , Chinmay Deshkar  , Suyog Vyas  , Umang Mantri
Published: May 2022

In this paper, an interactive software system for the enjoyment of the artworks in an art exhibition environment is presented. By using Augmented Reality technology, mobile application and High Resolution visualization we provide the users with a visual augmentation of the paintings and a touch interaction technique to display digital contents for art promotion, allowing exhibition visitors to interact with digital contents in an intuitive and exciting manner. The exhibition here presented is the result of previous research over the use of new technologies (e.g. Augmented Reality) for artwork promotion. Descriptions of the hardware system component and software development details are presented, with particular focus over the application implementation. Furthermore, we outline a possible Multi- media AR Installation connected with a semantic network.
Application Software : Boon For Teaching and Learning
Authors: Dr. Jasmeet Kaur Tandon  , Dr. Sarita Sharma
Published: May 2022

Application software is a set of programs to carry out a specific task like word processor, spreadsheet, presentation tools, library management software, railway reservation, antivirus software, etc. Generally an application software can perform only one specific job and cannot be used for something else. For instance, a library management software cannot be used for railway reservation system or a word processing software is generally not used as a spreadsheet
Advanced Lane Detection System for the Driver Assistance
Authors: Manisha Anil Dere  , Sanket Bhashkarrao Yengle  , Kamlesh W. Kelwade
Published: May 2022

Modern methods especially take route detection as a pixel problem-intelligent separation, difficult to deal with the challenge of challenge conditions and speed. Inspired by human vision, the recognition of the potential strong occlusion and extremely light conditions are based primarily on context general and global knowledge. Encouraged by this comment, we propose a novel, a simple yet effective design aimed at fast-paced and challenging. Specifically, we treat the route finding process as line-based problem solving using world features. With the help of line-based selections, our design can significantly reduce calculation costs. Great use a welcoming place in the global arena, we can also tackle a challenging situations. Moreover, based on construction, we also suggest building loss clearly show the structure of the routes. Comprehensive testing for two-way detection-benchmark data sets indicate that our method can reach the state of artistic performance in both speed and accuracy.
E-Hospicare Management System
Authors: Apeksha Dhone  , Nikeeta A. Narnaware  , Monika Jeswani  , Kalyani Bokade
Published: May 2022

This project E-Hospicare system includes registration of patients, storing their details into the system, and also computerized billing in the pharmacy, and labs. The software has the facility to give a unique id for every patient and stores the clinical details of every patient and hospital tests done automatically. It includes a search facility to know the current status of each patient. User can search details of a patient using the id. The E-Hospicare system can be entered using a username and password. It is accessible either by an administrator or receptionist. Only they can add data into the database. The data can be retrieved easily. The interface is very user-friendly. The data are well protected for personal use and makes the data processing very fast.
Detection of Malicious Social Boats Using Learning Automata with URL Feature
Authors: Apurva Sawant  , Shweta Sonawane  , Kirti Yewale  , Trupti Salunke  , Prof. Priyanka C. Kinage
Published: May 2022

Bots have made an impact on a variety of social media platforms. Twitter has been hit particularly hard, with bots accounting for a sizable amount of its user base. These bots have been used for nefarious purposes like distributing fake information about politicians and increasing celebrities' perceived popularity. These bots have the ability to alter the outcomes of standard social media analysis. Malicious social bots have also been employed to spread incorrect information (for example, emailing fraudulent urls), which can have real-world effects. To detect such hostile behaviors, the suggested systems employ machine learning methods such as Naive Bayes and RF.
Smart Door with Biometric Face Recognition and Thermal Screening
Authors: Senthil Kumaran V  , Sivan Surendhar R  , Venkatesh Prasad V  , Bharath P  , Dr. G. Udhayakumar
Published: May 2022

Since the outbreak of covid-19 it has become truly challenging to recognize the individuals who visit us at our home, offices, educational instituitions are influenced by the infection or not during this COVID19 pandemic. To tackle this issue as of now, temperature gadgets are regularly used. But these gadgets are not non-contact. With the development of artificial intelligence and computer vision, face recognition has become a hot topic of pattern recognition. While recognizing any individual, the most important attribute is face. It serves as an individual identity of everyone and therefore face recognition helps in authenticating any person’s identity using his personal characteristics. The whole procedure for authenticating any face data is sub-divided into two phases, in the first phase, the face detection is done quickly except for those cases in which the object is placed quite far, followed by this the second phase is initiated in which the face is recognized as an individual. Then the whole process is repeated thereby helping in developing a face recognition model which is considered to be one of the most extremely deliberated biometric technology. Our projects presents a conceptual model for providing entry access to an individual after face recognition and thermal screening. We will interface an IR temperature sensor to detect the temperature of an individual along with face detection to grant entry access. The proposed conceptual model can be helpful at every individual house, hospital to detect the temperature of the in-pateint and at institutions.
The Movie Recommendation System using Content Based Filtering with TF-IDF¬¬-Vectorization and Levenshtein Distance
Authors: Omkar Kunde  , Omkar Gaikwad  , Prathamesh Kelgandre  , Rohan Damodhar  , Prof. Mrs. M. M. Swami
Published: May 2022

In this busy life people like to do things to make their mind calm and watching movies is one of the thing but due to large data of a movie exist in the world it is very difficult for the user to select a movie. They have to spend a lot of time in searching and selecting movie. This procedure is time consuming and difficult. So recommendation system make the things easy. Recommendation engines are trained to produce fast and accurate suggestions to users. This paper describes a movie recommendation system using content based filtering and data is processed using Term-frequency Inverse document frequency technique (TF-IDF) for vectorization. Cosine similarity method is used for similarity measure. The system is presented to the user through a web-hosted user-interface which offers a system architecture by considering the initial problem usually faced by recommendation systems, namely the cold start problem. The problem of lack of user preferences data is trying to be overcome by utilizing movies data. The raw data is processed using the TF-IDF algorithm and Vector Space Model to generate a data model. Then levenshtien distance with cosine similarity will improve the performance of existing system. Advantages of the system include efficient recommendations, correct suggestions. Future enhancements include user profiling, documentations and data acquirement through web scraping.
Solar Panel Tracker Using PIC Microcontroller 16F628A
Authors: Mr. Bhavesh Anant Chavan
Published: May 2022

Energy sources are of two types renewable and non-renewable. ‘Renewable’ resources are those that recover their capacity in a time significant by human needs. Examples are sun light or wind power, when natural phenomenon that are the primary source of energy are going and not depleted by human demands. Now days, sometimes we complete our demand of electricity with the help of solar energy. This is done with the help of solar panels. By maintaining the solar panel always perpendicular to the incident sun rays we can receive maximum amount of energy. For this purpose, we have to set the tracker below the solar panel which always sets the panel orientation towards maximum intensity.
Impact of Occupational Stress on Job Satisfaction and Psychological Wellbeing
Authors: Dr. M. Dhanabhakyam  , Sarath. M
Published: May 2022

The teachers of self-finance colleges have the same responsibility while comparing with the aided and government college teachers but the environment is entirely different. They are not getting proper salary and denying PF, ESI and many other benefits also. These teachers community has been ignored by the management. So the occupational stress of self-finance college teachers is more while comparing with the other teachers. This study attempts to investigate the impact of occupational stress on psychological wellbeing and job satisfaction. The study also identifies the various factors influencing the occupational stress among teachers of self-finance colleges. Descriptive research design used for this study and data are collected through structured questionnaire.Simple random sampling method is used to select sample of 103 teachers from different self-financing colleges in Kozhikode district, Kerala. To measure the psychological well-being of teachers 18 items were used utilizing six components (Self-Acceptance, Positive Relations with Others, Autonomy, Environmental Mastery, Purpose in Life, and Personal Growth) developed by carol Ryﬀ. This study reveals that the occupational stress (work context, job content and organisational climate) has significant negative impact on job satisfaction and psychological wellbeing among teachers of self-finance colleges.
Utjecaj vjere na poimanje kvalitete života kod osoba s poremećajima živčanog sustava
Authors: Jeličić Ana , Grgić Tea
Published: May 2022

Cilj: Glavni cilj ovog istraživanja je utvrditi utjecaj vjere (i drugih dimenzija religioznosti) na subjektivnu procjenu opće kvali-tete života i ukupnog zadovoljstva kvalitetom života kod neuroloških pacijenata koji su po svojoj vjeroispovijesti kršćani.Metode: Šezdeset neuroloških pacijenata tijekom rehabilitacije u specijalnoj bolnici za medicinsku rehabilitaciju sudjelovalo je u istraživanju metodom anketnog upitnika. Korištena su tri upitnika: upitnik religioznosti, koji ima tri dimenzije, upitnik zado-voljstva kvalitetom života na sedam domena za odrasle (PWI) te upitnik koji sadrži jedno pitanje o zadovoljstvu kvalitetom života u cjelini. Rezultati: Duhovna dimenzija religioznosti ispitana je upotrebom osam čestica. Najveća razina utvrđena je kod čestice "Osje-ćam se vjernikom", a najmanja kod "Zbog svoje vjere spreman sam na odricanja i žrtvu". Najveća razina religioznosti utvrđena je kod obredne dimenzije, zatim kod duhovne, a najmanja kod dimenzije utjecaja vjere na ponašanje. Na temelju tri promatrane dimenzije religioznosti, zaključak je da kod ispitanih neuroloških pacijenata prevladava vrlo visoka razina religioznosti. Što se tiče zadovoljstva kvalitetom života na sedam domena, najzadovoljniji su odnosima s bližnjima, a najmanje su zadovoljni zdravljem. Zadovoljstvo kvalitetom života pokazalo se vrlo visokim kod oba mjerena upitnika. Testiranjem povezanosti religioznosti I (duhovne dimenzije) i zadovoljstva kvalitetom života na sedam domena te testiranjem povezanosti religioznosti I sa zadovoljstvom kvalitete života u cjelini, nije utvrđena povezanost. Testiranjem povezanosti između zadovoljstva životom na sedamdomena i zadovoljstva kvalitetom života u cjelini utvrđena je pozitivna, umjerena i statistički značajna povezanost.Zaključak: Na osnovu rezultata istraživanja zaključujemo da vjera može imati jedinstvenu ulogu u percepciji kvalitete života oboljelih te bi trebala postati dio standardne skrbi u liječenju pojedinca.
Prikaz slučaja kasnog tipa primarnog limfedema - od dijagnoze do uspješne terapije
Authors: Klarić Kukuz Ivana , Grančić Josipa , Poljičanin Ana , Marinović Ivanka , Aljinović Jure , Barić Žižić Ana , Pavlović Marta
Published: May 2022

We present a case report of a 46-year-old nurse with lower limb, late onset, second degree primary lymphedema diagnosed thirty years after symptoms onset. Lack of specialised lymphedema clinics, lymphedema specialists, lymphedema management guidelines and lymphedema registry are main causes for prolonged diagnosis in Croatia. Primary lymphedema treatment was con-ducted through 45-minutes sessions three times a week in total 7 sessions. Treatment sessions consisted of limb circumference mea-surements and manual lymph drainage followed by Partsch compression therapy protocol and education. Instructions for physical activity were made likewise. Significant volume reduction was successful despite long primary lymphedema duration. Changes in quality of life and physical activity were noted by self-administered questionnaires. Compression garment specialist made measures for flat knitted stockings compression class III. that are indicated for lymphedema and have important role in the maintenance phase of limb volume. Despite the fact that primary lymphedema is chronic condition, and it has been left untreated for over thirty years in our patient. With proper lymphedema therapy management and teamwork it is possible to achieve and maintain satisfying treatment results especially if you have motivated and properly educated patient.
The Relationship between Depression, Anxiety, Stress and Symptoms of Body Dysmorphic Disorder and Mediating Role of Self-Esteem in Cosmetic Surgery
Authors: Gajić Lena Dragana , Gajić Martina
Published: May 2022

Objectives: The objectives of the study were to examine the relationship between symptoms of body dysmorphic disorder (body image) and depression, anxiety, and stress as well as the mediating role of self-esteem in explaining this relationship in people undergoing cosmetic surgery. Methods: The following measurement instruments were used: (a) Sociodemographic variables; (b) The scale of depression, anxiety, and stress (DASS); (c) The Rosenberg Self-Esteem Scale (RSS); Appearance Anxiety Inventory; (AAI). Results: The results of the Pearson correlation coefficient showed that depression, anxiety, and stress were associated with the symptoms of Body dysmorphic disorder, and depression was the most significant. The results of hierarchical regression analysis, as well as mediation analysis, showed that self-esteem has a mediating role in the relationship between depression, anxiety, stress, and symptoms of Body dysmorphic disorder. Conclusions: This research opens new directions for research in the areas of depression, anxiety, stress, self-esteem, and body image in people who have undergone cosmetic surgery. It is also necessary to provide various psychoeducation programmes for the development of healthy ways of dealing with daily and life stressors, as well as support from psychotherapists whether it is anxiety, stress, depression, preoccupation with body image, or self-esteem.
Variables clínicas en el diagnóstico y tratamiento del cáncer de próstata avanzado hormono sensible
Authors: Zonana-Farca Elias , Ramírez-Pérez Erick Alejandro
Published: May 2022

En los últimos años han surgido informes de los novedosos estudios de imagen para aumentar la sensibilidad para detectar enfermedad metastásica temprana y por lo mismo, el reconocimiento de subgrupos biológicos de hombres en el escenario del cáncer de próstata avanzado recién diagnosticado en relación al manejo del tumor primario para mejorar la supervivencia general de estos pacientes considerados a tener enfermedad sistémica y con solo tratamiento de supresión androgénica, fatal a corto o mediano plazo.
Tiempo al PSA nadir como un factor de respuesta en pacientes con CPRC metastásico tratados con abiraterona
Authors: Sánchez-Martínez Néstor , Bautista-Vidal Carlos , Morales-Jiménez Pedro , García Galisteo Emilio
Published: May 2022

Objetivo: Objetivar si el tiempo a conseguir un PSA nadir se relaciona con retraso en la progresión de la enfermedad.
 
Material y métodos: Estudio retrospectivo de 36 pacientes tratados con acetato de abiraterona en nuestro centro entre enero de 2014 y mayo de 2018 en fase de resistencia a la castración (CPRC) M1. Evaluamos los niveles de PSA al inicio del tratamiento, después de 4, 8 y 12 semanas, así como en los periodos sucesivos según nuestro protocolo. La respuesta de PSA se define como una disminución de ≥30% desde el inicio del tratamiento y la progresión de PSA como un aumento de ≥25% desde el inicio. Se considera progresión que suponga retirada de tratamiento aquella que asocie al menos dos de los siguientes criterios: progresión de PSA, progresión clínica y progresión radiológica. Hemos realizado un análisis de regresión lineal para las variables PSA al diagnóstico, PSA nadir, tiempo al nadir, PSA doubling time y descenso de al menos un 30% del nadir.
 
Resultados: En nuestra serie, el tiempo al nadir en la regresión lineal se asocia de manera positiva con la progresión, obteniendo mejores supervivencias libres de progresión cuando se consigue un PSA nadir a más largo plazo (p<0.018); de manera que por cada mes de retraso en alcanzar el nadir se espera una progresión 0.8 meses más tardía.
 
Conclusiones: En nuestra serie alcanzar un PSA nadir más tardíamente se relaciona con una mejora en la supervivencia libre de progresión
Checkpoint inhibition: the current treatment of renal cell carcinoma
Authors: García-Robledo Juan Esteban , García-Perdomo Herney Andrés
Published: May 2022

Immune surveillance is one of the most important hallmarks of cancer. In the last decade many advancements in cancer treatment have been developed, much of them are related to the use of the immune system. Renal Cell Carcinoma is the most frequent type of kidney cancer followed by urothelial carcinoma. For years, treatment of Renal Cell Carcinoma has been conflictive as these tumors do not respond well to chemotherapy and have shown to be susceptible to immunotherapies as interferon and interleukin 2. The discovery of the immune checkpoints and their possible roles in cancer treatment led to the synthesis of novel drugs that can target and inhibit the interaction of certain molecules that are important for immunologic homeostasis. In this concise review, we summarize the evidence related with immune checkpoint inhibition for the treatment of renal cell carcinoma, especially for metastatic renal cell carcinoma.
Manejo de la lesión rectal durante la prostatectomía radical: Nuestra experiencia y revisión de la literatura
Authors: Sánchez-Llopis Anna , Blanco-Silvestre Marc , Abad-Carratalá Guillem , Martínez-Meneu Pedro , Monsonís-Usó Rosa , Barrios-Arnau Laura , Ponce-Blasco Paula , Garau-Perelló Carmen , Di Capua-Sacoto Carlos , Rodrigo-Aliaga Miguel
Published: May 2022

Objetivo: Evaluar la incidencia, los posibles factores de riesgo y el manejo de la lesión rectal durante la prostatectomía radical.
Diseño, metodología o aproximación: La lesión rectal es una complicación poco frecuente pero potencialmente grave de la prostatectomía radical (PR). La evidencia actual es limitada debido a que la mayoría de los estudios se basan en series relativamente pequeñas.
Se revisaron de manera retrospectiva un total de 147 prostatectomías radicales laparoscópicas de enero de 2017 a abril de 2021. Se encontraron 4 pacientes con lesión rectal durante el procedimiento.
 
Resultados: Del total de pacientes con lesión rectal durante el procedimiento existía extensión extraprostática en la RM precirugía en el 50% de los pacientes. Ninguno tenía antecedentes de RT previa. Se realizó cierre primario mediante dos capas de sutura en todos los casos. En un caso (25%) se realizó colostomía intraoperatoria. Uno de los cuatro pacientes (25%) desarrolló una fístula rectal con peritonitis secundaria por la que tuvo que ser reintervenido. El tiempo en dieta absoluta varió desde 0 días a 2 días y el tiempo de antibioterapia difirió en todos los pacientes.
 
Discusión: La lesión rectal ocurre en el 0.1-1.8% de pacientes sometidos a prostatectomía radical e incrementa de manera significativa la morbilidad del procedimiento. La mayoría de las lesiones rectales se producen durante las maniobras de disección del plano entre las vesículas seminales, la próstata y el recto. Para su detección se recomienda realizar un tacto rectal y insuflar aire por el recto intraoperatoriamente. Los factores de riesgo para su aparición son la RT previa, un tumor avanzado y una baja experiencia del cirujano en el procedimiento. La interposición de tejido en los defectos rectales sigue generando controversia. A pesar del cierre primario existe riesgo de fístula rectal, sobre todo en los casos de defectos mayores de 2 cm, RT previa o infiltración tumoral del recto.
 
Conclusiones: La lesión rectal es una complicación rara pero grave que puede complicar el postoperatorio de la prostatectomía radical.
IL-6 could regulate Th17/Treg cells to restore the local microenvironment of endometriosis
Authors: Jiang Jianfa , Feng Qing , He Sili
Published: May 2022

Introduction

In this study, we studied anti-IL-6 antibodies to treat endometriosis (EMS) by balancing Th17/Treg cells, providing a new basis for EMS research and treatment.

Material and methods

The rat EMS model was constructed to study the effect of anti-IL-6 on EMS. HE staining was performed to observe the lesions of the endometrium in rats. We have used anti-IL-6 to treat EMS rats. Then ELISA was used to measure the inflammatory factors IL-6, TGF-β and hormone estrogen levels in the rat serum. qRT-PCR and Western blot were used to measure estrogen receptor protein and apoptosis protein levels. Th17/Treg and CD163+/CD86+ ratios were determined by flow cytometry. CD34+ and CD163+ were measured by immunohistochemistry. TUNEL was performed to detect apoptosis in EMS lesions.

Results

The elevated levels of IL-6, TGF-β and estrogen in EMS rats indicated successful modeling. The ratio of Th17/Treg was imbalanced and raised. The ratio of Th17/Treg in anti-IL-6 rats recovered. The expression of FOXP3 in anti-IL-6 rats increased, and ROR-γt expression was suppressed. Anti-IL-6 could increase the apoptosis of the cells in the lesion. The size of the lesion was reduced. The expression of VEGF in the microenvironment of the lesions of EMS rats decreased.

Conclusions

IL-6 regulated Th17/Treg cells to restore the local microenvironment of EMS. Anti-IL-6 could regulate the immune microenvironment of EMS rats to alleviate the progression of EMS disease.
manifiesto a favor del cambio
Authors: El Editor
Published: May 2022

No hay resúmenes disponibles.
ECA Estudios Centroamericanos, Vol. 51, No. 573-574, 1996: 553-568.
Julio-agosto
Authors: El Editor
Published: May 2022

No hay resúmenes disponibles.

ECA Estudios Centroamericanos, Vol. 51, No. 573-574, 1996: 667-674.
Informe del Grupo Conjunto para la investigación de grupos armados ilegales con motivación política en El Salvador (29 de junio de 1994)
Authors: El Editor
Published: May 2022

No hay resúmenes disponibles.

ECA Estudios Centroamericanos, Vol. 51, No. 573-574, 1996: 675-708.
Propuestas de bienestar ¿con Estado de bienestar?
Authors: Ibisate Francisco Javier
Published: May 2022

El neoliberalismo, uno de los tantos "neos" de fines de siglo, proclama entre sus objetivos la consecución del bienestar social. Empero, ¿es posible conseguirlo, primero, sin un Estado de bienestar, y segundo, en una sociedad insolidaria, no estructurada para el bienestar? El autor contesta a las dos preguntas, echando una mirada al desarrollo histórico del Estado de bienestar y a su contraposición con el esquema neoliberal, su antípoda.

ECA Estudios Centroamericanos, Vol. 51, No.576, 1996: 865-887.
verdad detrás de la reconciliación
Authors: Duffy Helen
Published: May 2022

No hay resúmenes disponibles.
ECA Estudios Centroamericanos, Vol. 51, No. 576, 1996: 936-943.
Development and Evaluation of E-Learning Module in 3D Homes Designing
Authors: Art R. Napoles Michael
Published: May 2022

The primary purpose of this research is to develop an e-learning module for 3D Home Designing and assess the value of the instructional materials to the student's user. The pandemic forces our educational system to change to remote instruction, and the construction of the electronic module is crucial because there are no existing materials that focus primarily on 3D home design. Fifty (50) students enrolled in CAD courses tested the E-learning program. The mean and standard deviation were calculated using descriptive quantitative statistics in this investigation. The content of the e-learning program was evaluated using a survey questionnaire. In addition, the questionnaire requested input on the e-module. Following that, adjustments were made. The E-module is a helpful instrument in teaching 3D Homes Designing that encourages self-directed learning and direct application of knowledge.
Sikap Siswa Terhadap Pembelajaran Berbasis Online dilihat dari Berbagai Variabel
Authors: Cahyani Ariyani , Made Novi Suryanti Ni , Sukardi Sukardi
Published: May 2022

Penelitian ini dilatar belakangi oleh perubahan yang terjadi pada proses pembelajaran karena pandemi covid-19.  Perubahan yang terjadi adalah pembelajaran  dilakukan secara online. Penelitian ini merupakan penelitian kuantitatif yang bertujuan untuk mengetahui perbedaan sikap siswa terhadap pembelajaran berbasis online  dari  berbagai variabel (jenis kelamin, usia dan kelas). Subjek penelitian adalah seluruh Siswa-siswi  IPS di SMA Negeri 1 Gunungsari. Data dikumpulkan dengan membagikan questioner dengan bantuan google form. Analisis data  dilakukan menggunakan statistik deskriptif dan komparatif. Hasil penelitian menunjukkan bahwa: ada perbedaan sikap siswa teradap  pembelajaran  berbasis online pada masa pandemi covid-19 dari berbagai variabel (jenis kelamin, usia, kelas). Siswa perempuan, usia 16 tahun dan kelas X memiliki persepsi yang lebih baik terhadap pembelajaran berbasis online. Implikasinya adalah pembelajaran berbasis online perlu memperhatikan perbedaan variable-variabel tersebut dalam implementasinya.
Exploring the Relationship between Project Selection and Approval Criteria and Infrastructure Sustainability
Authors: Nana-Addy Edward , Musonda Innocent
Published: May 2022

This research aimed at compiling project selection criteria and modelling a robust criterion for infrastructure project selection and approval to enhance sustainability. The decision to select and approve sustainable infrastructure project for development must base on a robust criterion. To handle this properly, first, decision-makers must adopt a robust criterion that aid infrastructure sustainability. The study employed a systematic literature review, methodology and thematic analysis procedure to identify infrastructure project selection and approval criteria from literature. A total of 34 project selection criteria were identified and grouped into five categories. Besides, four approval requirements and four sustainable indicators have been discussed. To avoid any ambiguous and unclear questions in the criterion, 40 professionals were selected purposively for the pilot survey. Descriptive and inferential statistical analyses were employed, and findings were used to improve the criteria. The quantitative phase of the study was conducted on 320 stakeholders who were either project selectors, approvers, advisors, or designers responsible for government projects. S.E.M. were adopted for the analysis and testing of the hypothesis. Moreover, the study has proposed a structure model that integrates identified criteria and indicators to enhance infrastructure selection and approval. Continuous professional development training is vital for all stakeholders to understand and adopt the proposed project selection and approval criteria model to improve infrastructure sustainability performance and to enhance project selection and approval practices. And it was also included in the design brief as a deliverable factor. This outcome serves as preliminary and exploratory research to aid further study on the project selection and approval criteria model for infrastructure sustainability.]
The Comparison between the Studies of Corsani and Oberparleiter On the Subject of Risks and Functions within the Company
Authors: Carmine Boniello
Published: May 2022

The paper stems from the intent to deepen the contributions that two great scholars have given to two very important themes of business economics: the theme of business risks and that of business functions. In this paper, after highlighting the contributions of the two scholars on the issues covered by this paper, we will compare their studies highlighting the differences.
The Concept of the Causes and Effects of Risk in Some Italian and Foreign Scholars of the Twentieth Century
Authors: Carmine Boniello
Published: May 2022

In this paper we will examine the theme of risk and the causes related to it. We will highlight the studies conducted on these issues by various Italian and foreign scholars: each of them studied the concept of risk and the causes related to it from a different perspective. Finally, we will highlight that only the studies conducted by Corsani have succeeded in bringing true innovation to the concept of risk and related causes.
Experimental Analysis of Surface Defects in Electric Arc Welding Joints with Coated Electrode by Penetrant Test on Different Thicknesses
Authors: Berthé Chaka , Traoré Moussa Magara , Ouattara Tieba
Published: May 2022

Welding is considered today as the standard joining operation in steel construction. Its purpose is to ensure the continuity of the material to be assembled, the quality of which depends on the proper functioning of the welding technique. Penetrant testing is a non-destructive test that consists of implementing investigative techniques to judge "without destruction" the state of the weld joint. The final objective of this work is to develop an opinion on the suitability of the welding joint of different thicknesses. Thus, metal specimens of different thicknesses were inspected. The results obtained show that, for small thicknesses, the defects are minimal and increase considerably, proportionally with an increase in the thickness of the welded parts. This analysis can be a way to facilitate the location of surface defects in order to reduce defects during welding operations.
Business risk is a crucial node for the success of the business: Corsani's point of view
Authors: Carmine Boniello
Published: May 2022

Risk Theory can be defined as the discipline of science actuarial which studies the deviations of the results of a company with respect to the expected values. In this work we will first highlight the view that Corsani had regarding the theory of risk and then focus on risk factors in the strict sense and the transfer of risk.
Analysis of the Relationship between the Risk Management Strategies and Customers Satisfaction in the Golf Clubs in Nairobi City and Kiambu Counties
Authors: Mwangi Paul Nderitu , Maranga Vincent , Miricho Moses
Published: May 2022

The study sought to investigate the relationship between risk management strategies and customer satisfaction in the golf clubs in Nairobi City and Kiambu Counties, Kenya. A total of 17 golf clubs’ captains and 271 golfers/customers were targeted for this study. The crosssectional descriptive survey was adopted where semi-structured questionnaires, an interview schedule and secondary sources were used for data collection. The study established a statistically significant relationship between the risk management strategies and customer satisfaction with p=0.008
Business Risk Assessment and Measurement Tools: A Risk That the Company Must Manage for the Success of the Business
Authors: Carmine Boniello
Published: May 2022

Every company in its ordinary activity can run into multiple dangers that can evolve in an unfavorable direction to the company and compromise its development and economic stability with often irreversible consequences. In practice, it involves a complex of risks that could potentially affect the entire social and environmental context if not recognized and overcome. Risks can threaten a business's growth and existence. For this reason, in recent years, increasing attention has been paid to risk management in order to achieve corporate objectives. In the work we assessment center on risk assessment and assessment aims to attribute a value to the dimensions that risk the risk: the severity and frequency.
Cauchy an Innovative Mathematician: the Fundamentals of Infinitesimal Calculus, the Theorem of Finite Increments and the Functions of an "Imaginary" Variable
Authors: Carmine Boniello
Published: May 2022

Calculus is the founding branch of mathematical analysis that studies the "local behavior" of a function through the notions of continuity and limit, used in almost all fields of mathematics and physics and science in general. In the article we wanted to highlight through Cauchy the objectives of infinitesimal analysis expand and include complex analysis. In the second part of the work we concentrated on the finite increment theorem. It is one of the classical theorems of Mathematical Analysis, whose importance is justified by the fact that Lagrange's theorem turns out to be a trivial consequence. Finally, we will highlight its contribution to the functions of an imaginary variable: it is a contribution of fundamental importance for mathematics scholars of all times.
Finite Element Modelling of Rotors, Without Considering the Shear Effects
Authors: Ouattara Tieba , Traore Moussa Magara , Berthe Chaka
Published: May 2022

The proposed rotor model is based on the finite elements of a Timoshenko beam, whose support is rigid and fixed. It takes into account the geometric asymmetry of the discs and/or the shaft, while neglecting the shear effect. The equations of motion obtained include time-varying parametric terms that can lead to lateral dynamic instability. The influence of the combined rotational and translational movements of the support is analyzed by the Campbell diagram and the rotor stability map. Critical speeds according to modes have been identified.
Moderating Roles of Consumer Innovativeness in the Effect of Innovation Attributes on Brand Equity and Intention to Use: A Study in PT KAI Logistics
Authors: Prasetyanta Nindya Putra , Suryandari Retno Tanding
Published: May 2022

The present study aimed to find out the relationship between innovation attributes, consumer innovativeness, brand equity and intention to use KAI Logistics service, one subsidiary of PT KAI. The data were taken from 208 micro, small, and medium-scale businesses in Solo and Yogyakarta between May and July 2021, and analyzed using SmartPLS. This study found that innovation attributes significantly affected brand equity and intention to use. The result showed that consumer innovativeness and brand equity significantly affected the intention to use. Lastly, the study found that consumer innovativeness significantly moderated the effect of innovation attributes on brand equity and the intention to use railway Logistics services. This study provided KAI Logistic with feedbacks regarding policies and strategies to compete amid the covid-19 pandemic.
Public Debt Sustainability Assessment for Tunisia: Was the Stochastic Approach Powerful to Show Covid-19 Shock Impact?
Authors: Khalladi Hela Ben Hassine
Published: May 2022

To assess to which extent public debt in Tunisia is sustainable in the medium term, we apply a stochastic debt sustainability analysis, developped by Celasun, Debrun and Ostry in 2006. In contrast with the conventional debt sustainability analysis (DSA), this methodology explicitly takes into account the uncertainty characterizing the emerging markets, i.e the risks stemming from the interaction of the endogenous fiscal and macroeconomic shocks.
Investor-state Dispute under International Investment Law
Authors: Kopti Ala’a
Published: May 2022

Since the last century international investment law has been developing along with the increasing number of international investment agreements such as bilateral investment treaties aiming at efficient protection for foreign direct investment. The idea to introduce comprehensive protection for foreign direct investment appeared with the States started to perceive that foreign direct investment is a must for the prosperity of economic development of the countries. Since the international investment regime has emerged it started to become universal and uniform in the international economy. The establishment of the International Centre for Settlement of Investment Disputes was a crucial step for the protection of foreign direct investment in the international investment regime. The investor-state dispute settlement system has been developing through innovations introduced by parties of the international investment regime. However, Investor-State arbitration has remained as one of the most efficient mechanisms in the investor-state dispute settlement system throughout the years.