bluuebunny/crossref_metadata_2025 huggingface dataset:
MAFIA HUKUM DALAM PERSPEKTIF KEBERLANGSUNGAN DAN PENEGAKAN HUKUM
Authors: Surohmat Surohmat
Published: September 2023

Abstrak Secara empiris praktik mafia hukum berhubungan dengan adanya campur tangan pihak lain terhadap proses perkara yang sedang ditangani atau diproses oleh lembaga-lembaga penegak hukum. Sementara itu secara teoritis, praktik mafia hukum sangat merugikan dan menggangu keberlangsungan hukum dan proses penegakan hukum, yang menimbulkan masalah yang berkaitan dengan akibat yang ditimbulkan dari adanya praktik mafia hukum, dan penanggulangan  dan pencegahan praktik mafia hukum. Tulisan ini bermaksud meneliti tentang dampak yang ditimbulkan oleh praktik mafia hukum serta bagaimana kebijakan penanggulangannya. Penelitian menggunakan metode penelitian hukum normatif dengan pendekatan konseptual dan analitis. Dari hasil penelitian, ditemukan bahwa dampak dari praktik mafia hukum adalah melemahnya tingkat kesadaran masyarakat dan penegak hukum terhadap hakikat, substansi, dan proses penegakan hukum. Adapun kebijakan yang ditempuh untuk memberantas mafia hukum adalah menumbuhkan kesadaran masyarakat akan hukum, termasuk aparat penegak hukum yang terikat pada kode etik penegakan hukum. Kata Kunci: Mafia Hukum, Penegakkan Hukum, dan Kebijakan Hukum. AbstractEmpirically, the practice of the legal mafia is related to the interference of other parties in the process of cases being handled or processed by law enforcement agencies. Meanwhile, theoretically, the practice of mafia law is very detrimental and disrupts the continuity of the law and the process of law enforcement, which creates problems related to the consequences of the practice of mafia law and the prevention of mafia law practice. This paper intends to examine the impact caused by legal mafia practices and how to overcome them. The research uses normative legal research methods with a conceptual and analytical approach. From the results of the research, it was found that the impact of legal mafia practices is the weakening of the level of awareness of the public and law enforcers regarding the nature, substance, and process of law enforcement. The policy pursued to eradicate the legal mafia is to raise public awareness of the law, including among law enforcement officers who are bound by the law enforcement code of ethics.Keywords: Legal Mafia, Law Enforcement, and Legal Policy.
KEBIJAKAN SERTA PERLINDUNGAN HUKUM DALAM URGENSI LEGALITAS BAGI INDUSTRI MIKRO DI KOTA BOGOR
Authors: Ardiansyah Dicky , Muharram Nidhar Irham , Utama Raja Satria , Fadilah Zahra Rahmah
Published: September 2023

AbstrakPertumbuhan sektor industri dan perdagangan memiliki peran penting dalam perkembangan di bidang ekonomi. Usaha mikro kecil dan menengah (UMKM) yang tumbuh di tengah masyarakat menunjukkan daya tahan yang lebih tinggi dan menjadi penyangga perekonomian suatu negara maupun daerah.  Legalitas usaha adalah lisensi yang harus dimiliki oleh semua pengusaha. Legalitas usaha ini berperan asistensi peraturan bagi para pedagang, oleh karena itu pengusaha harus memimpin legalitas usahanya. Surat izin ini bertujuan untuk menghamparkan peraturan legalitas dan urgensi legalitas usaha. Penelitian ini dilakukan secara kualitatif dengan menggunakan tata cara penentuan hukum normatif. Sumber bukti pada saat penulisan ini yaitu data sekunder dan penelitian perpustakaan, khususnya mengenai peraturan perundang-undangan di bidang perindustrian. Hasil pemeriksaan menunjukkan bahwa legitimasi bisnis sangat penting bagi pengusaha. Menurut Pasal 10 Undang-Undang Bisnis Nomor 3 Tahun 2014, setiap bidang kegiatan harus menyimpan izin kegiatan. Oleh karena itu legalitas usaha sangat penting bagi pengusaha, karena izin usaha ini bisa berperan sebagai penyokong hukum bagi pengusaha.Kata Kunci: Industri, UMKM, legalitas, izin, legitmasi, pengusaha. AbstractThe growth of the industrial and trade sectors has an important role in developments in the economic field. Micro, small and medium enterprises (MSMEs) that grow in the midst of society show higher resilience and become a pillar of the economy of a country or region. Business legality is a license that must be owned by all entrepreneurs. The legality of this business plays a regulatory role for traders, therefore entrepreneurs must lead the legality of their business. This permit aims to spread legality regulations and the urgency of business legality. This research was conducted qualitatively using normative legal determination procedures. Sources of evidence at the time of writing were secondary data and library research, particularly regarding laws and regulations in the industrial sector. The results of the examination show that business legitimacy is very important for entrepreneurs. According to Article 10 of the Business Law Number 3 of 2014, every field of activity must keep an activity permit. Therefore business legality is very important for entrepreneurs, because this business license can act as a legal support for entrepreneurs.Keywords : Industrial, MSMEs, legality, license, legitimacy, entrepreneur.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KELELAHAN KERJA DI DEPARTMENT AREA PRODUKSI MCD, PLANT M, PT “X” TAHUN 2017
Authors: Rahayu Ririn Puji , Effendi Luqman
Published: September 2023

Data dari ILO tahun 1998 menyebutkan hampir setiap tahun sebanyak 2 juta pekerja meninggal dunia karena kecelakaan kerja yang disebabkan oleh faktor kelelahan kerja. Penelitian tersebut menyatakan dari 58.115 sampel, 32,8% diantaranya atau sekitar 18.828 sampel menderita kelelahan. Penelitian ini bertujuan untuk meneliti faktor-faktor yang berhubungan dengan kelelahan kerja di Department Area Produksi MCD, Plant M, PT. “X”, Tahun  2017. penelitian ini menggunakan metode penelitian kuantitatif dengan desain studi cross sectional. Populasi dalam penelitian ini adalah seluruh pekerja di Department Area Produksi MCD, Plant M, PT ”X”. Jumlah responden sebanyak 109 orang diambil dengan teknik accidental sampling dan dianalisis dengan analisis univariat dan analisis bivariat.  Berdasarkan hasil analisis univariat, responden yang paling banyak mengalami kelelahan sedang (51,4%), berusia 23 tahun (10,1%), status normal(47,7%), tidak memiliki riwayat penyakit (72,5%), riwayat penyakit dengan gangguan pencernaan (14,7%), kebiasaan merokok (52,3%), <10 batang/hari (33,9%), bekerja secara shif (87,2%), terpapar ≥85 Dba (60,6%). Berdasarkan hasil analisis bivariat, terdapat variabel yang menunjukan adanya hubungan yang signifikan dengan kelelahan yaitu variabel kebiasaan merokok ( p=0,045, OR=2,4; CI95%=1,0-5,3 ), shift kerja ( p=0,005, OR=5,6; CI95%=1,6-19,6 ) dan kebisingan ( p=0,000, OR=5,1; CI95%=2,2-12,0 ). Sedangkan variabel yang tidak ada hubungan dengan kelelahan adalah usia, status gizi, dan riwayat penyakit.---Data from the ILO in 1998 states that almost 2 million workers die every year due to work accidents caused by work fatigue. The study stated that of 58,115 samples, 32.8% of them or around 18,828 samples suffered from fatigue. This study aims to examine the factors associated with work fatigue in the MCD Production Area Department, Plant M, PT. "X", 2017. This study uses quantitative research methods with cross sectional study design. The population in this study were all workers in the MCD Production Area Department, Plant M, PT "X". The number of respondents was 109 people taken by accidental sampling technique and analyzed by univariate analysis and bivariate analysis. Based on the results of univariate analysis, the respondents who experienced the most moderate fatigue (51.4%), aged 23 years (10.1%), normal status (47.7%), had no history of disease (72.5%), history diseases with digestive disorders (14.7%), smoking habits (52.3%), <10 cigarettes / day (33.9%), working as a shif (87.2%), exposed to ≥85 Dba (60.6%) %). Based on the results of bivariate analysis, there are variables that show a significant relationship with fatigue, namely the smoking habit variable (p = 0.045, OR = 2.4; CI95% = 1.0-5.3), work shift (p = 0.005, OR = 5.6; CI95% = 1.6-19.6) and noise (p = 0.000, OR = 5.1; CI95% = 2.2-12.0). While the variables that are not related to fatigue are age, nutritional status, and disease history.
Profil dan Beberapa Faktor yang Berhubungan dengan Hemostasis Pasien Diabetes Melitus Tipe 2 Tak Terkontrol
Authors: Ajin Mukhyarjon Muslim , Wahid Irza , Manaf Asman
Published: September 2023

Hiperkoagulasi merupakan salah satu faktor risiko terjadinya penyakit kardiovaskuler. Resistensi insulin dan hiperglikemia yang meningkat pada diabetes melitus tipe 2 (DMT2) tidak terkontrol, memainkan peran penting dalam patogenesis terjadinya hiperkoagulasi. Meskipun banyak studi telah dilakukan, namun penelitian pada subjek di Indonesia masih terbatas.  Penelitian ini bertujuan mengetahui profil dan faktor-faktor yang berhubungan dengan hemostasis pada pasien DMT2 tak terkontrol. Ini merupakan studi analitik observasional dengan rancangan potong lintang. Lima puluh pasien diabetes melitus (DM) tak terkontrol berpartisipasi pada penelitian ini. Variabel bebas meliputi umur, onset dan jenis kelamin, sedangkan variabel terikat adalah prothrombine time (PT), activated partial thromboplastin time (APTT), fibrinogen dan D-dimer. Data dianalisis menggunakan uji Chi-Square dan nilai p<0,05 dianggap bermakna. PT yang rendah tidak ditemukan pada penelitian ini sementara APTT yang rendah ditemukan pada 2% pasien. Hiperfibrinogenemia ditemukan pada 34% pasien dan D-dimer tinggi ditemukan pada 28% pasien. Terdapat hubungan hiperfibrinogenemia dengan onset DM namun tidak dengan umur dan jenis kelamin. D-dimer tinggi berhubungan dengan usia namun tidak dengan gender dan onset penyakit. Studi ini dapat disimpulkan bahwa hiperfibrinogenemia dan D-dimer tinggi sering ditemukan pada pasien DMT2 tidak terkontrol sehingga evaluasinya perlu dipertimbangkan terutama pada DMT2 yang disertai faktor-faktor risiko penyakit kardiovaskuler yang lain.
Efek Inhibitor Proteasom terhadap Histopatologi Arteri Koronaria pada Tikus Model Aterosklerosis
Authors: Ismawati Ismawati , Romus Ilhami , Utami Elfima Aditya
Published: September 2023

Penelitian sebelumnya menunjukkan peranan proteasom pada setiap tahap aterosklerosis yaitu tahap inisiasi, progresi dan komplikasi. Hal ini mendorong penelitian inhibitor proteasom sebagai terapi aterosklerosis dan bortezomib merupakan inhibitor proteasom yang pertama kali dikembangkan. Pada penelitian ini akan dianalisis efek pemberian inhibitor proteasom (bortezomib) terhadap pembentukan lesi aterosklerosis pada arteri koronaria tikus model aterosklerosis tahap progresi. Penelitian ini menggunakan 15 ekor tikus (Rattus novergicus) strain Wistar jantan yang dibagi menjadi 3 kelompok yaitu kelompok kontrol (I), kelompok aterosklerosis (II), dan kelompok aterosklerosis dengan pemberian bortezomib (III). Induksi aterosklerosis dilakukan dengan pemberian vitamin D3 (700.000 IU/kg) secara oral, dan dilanjutkan dengan diet aterogenik (kolesterol 2%, lemak kambing 5%, asam kolat 0,2 % dan diet standar 100%) selama 4 hari. Pemberian bortezomib dosis rendah (50 μg/kgBB) pada hari ke-1 dan ke-3 secara intraperitoneal. Penilaian lesi aterosklerosis dilakukan dengan sistem skoring. Hasil penelitian didapatkan skor lesi tertinggi pada kelompok model aterosklerosis dan adanya penurunan rerata skor lesi aterosklerosis pada kelompok aterosklerosis yang diberi bortezomib (0,70 vs 0,44, p<0,05). Disimpulkan bahwa pemberian bortezomib dapat menghambat pembentukkan lesi aterosklerosis pada tahap progresi.
Faktor-Faktor yang Memengaruhi Kepatuhan Peserta Mandiri Membayar Iuran BPJS di Kelurahan Benda Baru
Authors: Latifah Noor , Nabila Wafa , Fajrini Fini
Published: September 2023

Badan Penyelenggara Jaminan Sosial (BPJS) merupakan badan penyelenggara yang kepesertaannya bersifat wajib sebagaimana tertuang dalam UU No.40 Tahun 2004. Di wilayah Banten, Kota Tangerang Selatan menduduki peringkat ke-2 sebagai wilayah dengan peserta BPJS terbanyak memiliki tunggakan dalam pembayaran BPJS di mana Kecamatan Pamulang memiliki jumlah tunggakan tertinggi yaitu 32.484 jiwa dan Kelurahan Benda Baru memiliki jumlah tunggakan tertinggi sebesar 4.586 jiwa. Iuran sangat berpengaruh terhadap kelancaran berjalannya BPJS Kesehatan agar tidak terjadi defisit. Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang Memengaruhi kepatuhan peserta mandiri dalam membayar iuran BPJS di Kelurahan Benda Baru. Penelitian dilakukan di Kelurahan Benda Baru, Kecamatan Pamulang Kota Tangerang Selatan pada bulan Juli-Agustus Tahun 2019. Sampel yang diambil adalah peserta BPJS mandiri sebanyak 102 orang. Desain penelitian menggunakan cross sectional dengan  teknik pengambilan data purposive sampling. Analisis dilakukan dengan uji univariat dan bivariat dengan uji chi-square. Ada hubungan antara pengetahuan dengan kepatuhan peserta mandiri dalam membayar iuran BPJS (p-value = 0,000). Perlu adanya sosialisasi secara rutin dari petugas BPJS Kesehatan mengenai informasi pembayaran iuran tepat waktu.
Persepsi Pasien Dalam Implementasi Pelayanan Kesehatan Pada Masa Pandemik COVID-19 di Wilayah Kota Bekasi Tahun 2020
Authors: Puspita Nadya Rahma , Mustakim Mustakim
Published: September 2023

Masa pandemik telah terjadi beberapa bulan dan memberikan dampak psikologis masyarakat, seperti timbul rasa panik dan cemas, dikarenakan kurangnya gambaran umum masyarakat tentang penjelasan mengenai COVID-19 dan bagaimana implementasi pelayanan kesehatan dalam menyikapi COVID-19. Tujuan penelitian dilakukan untuk mengetahui gambaran persepsi pasien terhadap implementasi pelayanan kesehatan selama masa pandemik COVID-19 di wilayah Kota Bekasi. Studi penelitian menggunakan desain studi cross sectional yang bertujuan untuk mengetahui gambaran persepsi kepuasan pasien terhadap implementasi pelayanan kesehatan selama masa pandemik COVID-19 di wilayah Kota Bekasi. Purposive sampling dipilih sebagai teknik pengambilan sampel dengan kriteria yaitu pasien yang berobat/berkunjung ke fasilitas pelayanan kesehatan pada bulan Maret sampai bulan Juni tahun 2020, fasilitas pelayanan kesehatan yang dikunjungi berada di wilayah Kota Bekasi, dan pasien bersedia menjadi responden dalam penelitian. Sampel dalam penelitian ini sebanyak 107 sampel. Hasil dari penelitian menunjukkan 52,3% memiliki persepsi bahwa penerapan pengendalian teknis sudah sesuai, 56,1% memiliki persepsi bahwa penerapan pengendalian administratif sudah sesuai, dan 52,3% memiliki persepsi bahwa penerapan Alat Pelindung Diri (APD) di pelayanan kesehatan wilayah Kota Bekasi sudah sesuai. Dengan demikian dapat dinyatakan bahwa pelayanan kesehatan di Kota Bekasi telah mengimplementasikan pelayanan kesehatan dengan program pencegahan dan pengendalian infeksi yang sesuai selama masa pandemik COVID-19.
Gambaran Radiologi Foto Toraks Pasien TB Paru Resistan Obat dengan dan Tanpa DM Tipe 2 di Rumah Sakit Islam Jakarta Sukapura
Authors: Fachri Muhammad , Fauzi Reza Ahmad , Akaputra Risky
Published: September 2023

Diabetes Mellitus (DM) merupakan faktor risiko perkembangan TB aktif. DM adalah penyakit tidak menular yang bersifat kronis dan akan melemahkan sistem kekebalan tubuh, penderitanya memiliki kemungkinan 3 kali lebih tinggi untuk menderita TB aktif. Tujuan penelitian ini adalah mengkaji gambaran radiologi foto toraks pasien TB paru resistan obat disertai DM tipe 2 dibandingkan dengan pasien TB paru resisten obat tanpa DM tipe 2 di RSIJ Sukapura periode September 2018 – September 2019. Penelitian ini adalah penelitian deskriptif komparatif dengan rancangan penelitian cross sectional (potong lintang). Teknik pengambilan sampel adalah total sampling serta menggunakan data sekunder. Jumlah sampel sebanyak 9 pasien, 5 pasien perempuan dan 4 pasien laki-laki. 4 pasien dengan DM dan 5 pasien bukan DM. Infiltrat adalah gambaran yang banyak ditemukan pada pasien DM dan bukan DM. Pada pasien DM kavitas dan fibrosis merupakan gambaran yang sering ditemukan setelah infiltrat. Pada pasien bukan DM nodul merupakan gambaran yang sering ditemukan setelah infiltrat. Pada penelitian ini menunjukkan hasil tidak terdapat perbedaan yang signifikan antara pasien DM maupun bukan DM.
Gambaran Kualitas Tidur pada Lansia dan Faktor-Faktor yang Mempengaruhinya di Kecamatan Kayangan, Kabupaten Lombok Utara, Nusa Tenggara Barat
Authors: Hasibuan Robiah Khairani , Hasna Jullinar Aulia
Published: September 2023

Gangguan Tidur merupakan suatu kumpulan kondisi yang dicirikan dengan gangguan dalam jumlah, kualitas atau waktu tidur pada seorang individu. Seorang lansia akan membutuhkan waktu lebih lama untuk masuk tidur (berbaring lama di tempat tidur sebelum tertidur) dan mempunyai lebih sedikit atau lebih pendek waktu tidur nyenyaknya. Tujuan penelitian ini adalah diketahuinya prevalensi dan faktor-faktor yang mempengaruhi gangguan tidur. Penelitian ini adalah penelitian deskriptif analitik dengan pendekatan Cross-Sectional. Pengambilan sampel dilakukan dengan menggunakan teknik consecutive sampling. Instrumen yang digunakan adalah Pittsburgh Sleep Quality Index (PSQI). Analisis dilakukan dengan chi-square. Berdasarkan uji chi-square diketahui terdapat korelasi antara status merokok (p=0,034, OR=1,974, 95%CI=1,048±3,721) dan tingkat kecemasan (p=0,013, OR=0,482, 95%CI=0,270±0,859) dengan kejadian Gangguan Tidur. Penelitian tidak dapat membuktikan adanya korelasi antara jenis kelamin, usia, tingkat pendidikan, status pekerjaan, penghasilan perbulan, konsumsi kopi, konsumsi alkohol, tekanan darah, indeks massa tubuh, gula darah puasa, kolesterol dan asam urat dengan kejadian Gangguan Tidur.
Hubungan Personal Hygiene dengan Kejadian Penyakit Dermatitis di Wilayah Kerja Puskesmas Poris Gaga Lama Tahun 2021
Authors: Ernyasih Ernyasih , Sari Juju Permata , Fauziah Munaya , Andriyani Andriyani , Lusida Nurmalia , Herdiansyah Dadang
Published: September 2023

Berbagai macam penyakit kulit saat ini masih menjadi masalah kesehatan masyarakat di dunia, termasuk Indonesia. Penyakit dermatitis termasuk 5 penyakit terbanyak di Puskesmas Kota Tangerang pada tahun 2016 sebesar 5,44%. Penyakit Dermatitis di Puskesmas Poris Gaga Lama pada tahun 2020 berada di peringkat ke-enam dengan jumlah penderita sebanyak 950 orang. Penelitian ini bertujuan untuk mengetahui hubungan personal hygiene dengan kejadian penyakit dermatitis di wilayah kerja Puskesmas Poris Gaga Lama tahun 2021. Penelitian ini menggunakan desain studi case control dan pengambilan sampel menggunakan teknik Purposive Sampling pada 72 jumlah responden. Analisis yang digunakan adalah analisis univariat menggunakan uji proporsi dan bivariat dengan menggunakan uji chi square. Hasil penelitian menunjukkan ada hubungan dengan kejadian penyakit dermatitis yaitu tingkat pendidikan (p value=0,004 dan OR=0,204), kebersihan kulit (p value=0,026 dan OR=4,522), dan kebersihan pakaian (p value=0,038 dan OR=0,280). Perlu adanya sosialisasi atau penyuluhan mengenai pentingnya menjaga PHBS serta adanya kesadaran dari masyarakat untuk selalu menjaga kebersihan diri serta lingkungan agar tidak terjadi penyakit dermatitis.
MITIGASI PENGURANGAN RISIKO BENCANA BANJIR DI DESA CIPAYUNG KEC. MEGAMENDUNG. KAB. BOGOR MENGGUNAKAN TEKNOLOGI INTERNET OF THINGS (IoT)
Authors: Muhendra Rifki , Solihin Solihin
Published: September 2023

Sungai ci Esek merupakan sungai yang terletak di desa Cipayung kecamatan Megamendung Kabupaten Bogor yang memiliki arus yang besar terutama ketika hujan. Beberapa bagian desa dan desa lainnya yang berada di sekitar desa Cipayung merupakan daerah terdampak banjir. Pada kegiatan pengabdian masysrakat ini tim dari Universitas Bhayangkara Jakarta Raya telah berhasil mengembangkan system monitoring potensi banjir sebagai salah satu langkah mitigasi bencana daerah di kabupaten bogor. System ini terdiri dari perangkat sensor yang dapat mengukur ketinggian permukaan sungai dan curah hujan dimana data-data fisik ini dikirimkan ke Internet. Akses data potensi banjir ini dapat dilakukan secara real time dan jarak jauh menggunakan perangkat mobile dan computer internet. System ini juga telah diuji dilapangan dengan pemasangan perangkat sensor di pinggir sungai ci Esek dimana rata-rata data yang dikumpulkan setiap hari sebesar 1429. Persentasi kehilangan data adalah 0,75%. Ini membuktikan system dapat digunakan sebagai salah satu upaya preventive dalam menghadapi potensi banjir di Kabupaten Bogor.
Quantifying the Influences of Land Use and Rainfall Dynamics on Probable Flood Hazard Zoning
Authors: Nabi Rehman  , Zada Umar , Kashif Haleem
Published: September 2023

Flooding is Pakistan's most common natural hazard, and it is exacerbated by increased rainfall and urbanization. Khyber Pakhtunkhwa (KPK), Pakistan flood-prone zones were determined by superimposing six flood parameters in an ArcGIS environment: elevation, slope, rainfall accumulation, land cover, soil geometry, and gap/buffer from water channel. Cellular automata based on artificial neural network (CA-ANN) along QGIS plugin module of Land Use Change Simulations (MOLUSCE) was used for predicting year 2050 land use, with a kappa value of 0.83. The results indicated that of the 75775 km2 land area covered by this research region, 3.37% (2553.62 km2) falls in extremely high risk, 18.44% (13972.91 km2) falls in high risk, 11.26% (8532.27 km2) falls in moderate risk, 0.51% (386.45 km2) falls in low risk, and just 66.42% (50329.76 km2) falls in very low risk areas. In KPK, like in any other place, a multi-criteria flood risk-vulnerability assessment is consequently necessary for preparation and post-hazard planning. Without a doubt, the outcomes reported here are crucial for flood risk assessments and hazard management decision-making.

Key words:  natural disasters; floods; remote sensing; geographic information system, multi-criteria evaluation; weighted overlay.
Medicinal Mushroom, Ganoderma Lucidum, Improves Painful Symptoms in Patients with Restless Legs Syndrome
Authors: Bugnicourt Jean-Marc
Published: September 2023

Restless legs syndrome (RLS) is a prevalent sensorimotor sleep disorder that worsens quality of life. All the currently available drug treatments for RLS have limitations. Extracts of the mushroom Ganoderma lucidum (GL) have shown several beneficial biological effects in neurodegenerative diseases. The objective of the present study was to evaluate the effect of a 2-month course of GL extract on the intensity of painful RLS symptoms.
Early Infantile Krabbe Disease Due To a Novel Compound Heterozygous Mutation in a Tunisian Family
Authors: Ketata Imen , Ellouz Emna
Published: September 2023

Krabbe disease is a rare lysosomal storage illness caused by a mutation in the Galc gene. It characterized by severe neurological and metabolic disorders. The early infantile form is the most common. Regardless of the non-specific signs, diagnosis could be challenging. Over time, novel gene variants are uncovered.
Perspektif Hak Asasi Manusia dalam Pemenuhan Atas Jaminan Hari Tua
Authors: Larasati Try Anggie , Setiawan Dian Bakti , Alsyam Alsyam
Published: September 2023

Old-Age Security (JHT) is an employment social security program that has the objective of providing cash benefits through a lump sum payment when participants enter retirement age, pass away, or experience permanent total disability. Where this mechanism is the embodiment of the mandate of Article 28H Paragraph (3) of the 1945 Constitution. However, the practice of implementing JHT has experienced several problems, for example changing implementing regulations in a short time, which raises two problems: First, regarding the dynamics of JHT arrangements in Indonesia, and the perspective of Human Rights in the implementation of JHT. This study uses a normative juridical method with library data collection techniques. This study concludes that the regulatory changes that have occurred in the regulations surrounding JHT are the government's efforts to adapt regulations to developments so that workers can enjoy JHT, but the government is not optimal in disseminating regulations to JHT beneficiaries. Meanwhile, from a human rights perspective, it can be concluded that the government is already present in realizing the fulfillment of the right to social security through JHT, which is through a legal umbrella in the form of Government Regulations and Ministerial Regulations. It's just that changing legal products in a short time is the main obstacle that has resulted in JHT not running optimally, so that workers have not been able to fully enjoy the fulfillment of their rights to JHT. Therefore, this study concludes that the government needs to create permanent regulations that do not require changes in a short time to fulfill JHT rights as a form of legal certainty.
Cytomorphological findings in drug defaulters of tuberculous lymphadenitis
Authors: Kumari Aarti , Ahuja Sana , Bajaj Sachin , Zaheer Sufian , Chaitanya Vinod , Agarwal Yatish , Gupta Ratan , Ranga Sunil
Published: September 2023

Objectives:

Tuberculosis (TB) is an important health problem specially in the developing countries. Although effective chemotherapy is available, compliance of patient is a major challenge. The aim of this study was to describe cytomorphological features of drug defaulters on lymph node on fine-needle aspiration cytology (FNAC) and compare it with newly diagnosed cases.

Material and Methods:

A cross-sectional study was done for a period of 18 months, in which all patients having tuberculous lymphadenitis were included after taking detailed history regarding previous anti-TB drug intake. Cytomorphological findings in drug defaulters were evaluated and compared with newly diagnosed cases.

Results:

There were a total of 150 cases with 120 newly diagnosed and 30 drug defaulters. Splintered epithelioid cell granuloma was seen in 40% of drug defaulters, while it was absent in case of newly diagnosed cases (P < 0.0001). Well-formed epithelioid cell granuloma was most commonly seen in newly diagnosed cases (65.83%) followed by poorly formed granuloma (26.67%). Another significant finding was distribution of eosinophils which were significantly high in case of drug defaulters (56.67%) (P < 0.0001).

Conclusion:

Cytomorphological findings can help in identification of the drug defaulters on FNAC and thus plan further line of treatment.
Surgical Audit of Operated Patients in a Tertiary Care Hospital in Karachi, Pakistan
Authors: Akhtar Huma , Ahmed Hajrah Hilal , Irshad Kanwal , Jamaluddin Muhammad
Published: September 2023

Objectives

To audit operated patients in emergency and electively from 1st January 2018 to 31st December 2019 in all three surgical departments to know the outcome of the patients at a tertiary care hospital in Karachi, Pakistan.

Material and Methods

A retrospective study conducted in all three Abbasi Shaheed Hospital surgical units from 1st January 2018 to 31st December 2019. In this study total of 5079 patients were included who were admitted through the emergency and surgical outpatient department. They were operated in emergency and elective theaters in all three surgical departments of Abbasi Shaheed Hospital. Data was collected on pre-designed performa from emergency and elective theater, wards, High-dependency unit and Intensive care unit maintained registers by staff.

Results

A total of 5079 cases were operated during January 2018 to December 2019. Among all the age ranges 1282 belongs to the age range of 21-30 years. Amongst which 59.6% were males. The most common diagnosis made in elective patients was chronic calculous cholecystitis (25.8%) and an abscess in emergency (39.4%). The most common procedure performed in elective surgeries was combined laparoscopic and open cholecystectomy (26.8%) and incision and drainage in the emergency (39.4%). Elective surgeries were mainly performed by Associate Professors (28.7). While, emergency surgeries were mainly performed by post-graduate trainees (70.2%). Surgical unit II has performed most surgeries (39.5%). Elective procedure constitutes about (51.60%). Total 19 patients expired out of 350 patients who were shifted or admitted in surgical ICU and 12 patients expired in all three wards.

Conclusion

We have a higher number of elective surgeries as compared to the emergency surgeries. Consultants have performed most of the elective surgeries. Emergency surgeries mostly by residents and senior registrars. We have zero mortalities in our elective surgeries in comparison with emergency surgeries. We call attention to conduct continuous audits at our hospitals and all levels of health care and demand from higher authorized personnels to incorporate audit awareness in our teaching. Along with it, a proper database should be installed with updated records maintenance to improve the lack of health care.
Empty Nose Syndrome with Unilateral Ethmoidal Mucopyocoele – An Extremely Rare Presentation
Authors: Rizvi Sama , Kalra Rishita , Pathak Vivek Kumar , Nayak Pradeepti
Published: September 2023

Introduction

Empty nose syndrome (ENS) is a poorly understood and rare iatrogenic disorder resulting from the destruction of normal nasal tissue. ENS is a recognized complication after turbinate excision. These patients suffer from endonasal crusting and dryness and a paradoxical sensation of nasal obstruction. These complications of ENS predispose these patients to recurrent sino-nasal infections.

Case report

Here we have reported the case of a 20-year-old female with right-sided nasal obstruction and headache. On diagnostic nasal endoscopy (DNE), the right nasal cavity was devoid of all anatomical landmarks. A hidden ethmoidal mucopyocoele was identified on radiological evaluation . This was drained surgically. Patient’s symptoms improved drastically postoperatively.

Conclusion

Despite the fact that occurrence of rhino-sinusitis is common in patients of ENS, a mucocoele or mucopyocoele has never been reported previously. To the best of our knowledge, this is the first ever reported case of ENS with ethmoidal mucopyocoele in a young, immuno-competent patient.
Long-term Plasmapheresis for Cholestatic Pruritus
Authors: Sanson Erik , Richard Luke J , German Margarita N , Rose William N
Published: September 2023

Cholestatic pruritus is commonly associated with many hepatobiliary disorders and can be typically controlled with conventional treatment. Therapeutic plasma exchange (TPE) has shown success in improving untreatable cholestatic pruritus with great success. We report on the use of TPE to alleviate debilitating pruritus in one patient with a two-year history of chronic pruritus refractory to conventional treatment. The patient presented with an acute onset of diffuse pruritus that did not fully respond to first or second-line treatments, including bile acid sequestrants. Pruritus significantly affected her quality of life, interfering with daily activity, causing insomnia and weight loss. Due to the severity of her symptoms, biweekly TPE with 5% albumin infusions were initially trialed. Patient found symptoms to be much improved until about the fifth day after each TPE. TPEs were scheduled twice per week alternating with once per week. TPE appeared to be an effective treatment for this patient with chronic cholestatic pruritus. For our patient, TPE seemed to provide relief for about 3-5 days after each TPE.
Zero-Field Splitting Parameters within Exact Two-Component Theory and Modern Density Functional Theory Using Seminumerical Integration
Authors: Bruder Florian , Franzke Yannick J. , Holzer Christof , Weigend Florian
Published: September 2023

An efficient implementation of zero-field splitting parameters based on the work of Schmitt et al. [J. Chem. Phys. 134, 194113 (2011)] is presented. Seminumerical integration techniques are used for the two-electron spin–dipole contribution and the response equations of the spin–orbit perturbation. The original formulation is further generalized. First, it is extended to meta-generalized gradient approximations (meta-GGAs) and local hybrid functionals. For these functional classes, the response of the paramagnetic current density is considered in the coupled-perturbed Kohn–Sham (CPKS) equations for the spin–orbit perturbation term. Second, the spin–orbit perturbation is formulated within the relativistic exact two-component (X2C) theory and the screened nuclear spin–orbit (SNSO) approximation. Accuracy of the implementation is demonstrated for transition-metal and diatomic main-group compounds. The efficiency is assessed for Mn and Mo complexes. Here, it is found that coarse integration grids for the seminumerical schemes lead to drastic speedups while introducing clearly negligible errors. Additionally, the SNSO approximation substantially reduces the computational demands and leads to very similar results as the spin–orbit mean field (SOMF) ansatz.
What is the nature of the uranium(III)-arene bond?
Authors: Roy Chowdhury Sabyasachi , A. P. Goodwin Conrad , Vlaisavljevich Bess
Published: September 2023

Complexes of the form [U(η 6 − arene)(BH 4 ) 3 ] where arene = C 6 H 6 ; C 6 H 5 Me; C 6 H 3 -1,3,5-R 3 (R = Et, iPr, tBu, Ph); C 6 Me 6 ; and triphenylene (C 6 H 4 ) 3 were investigated towards an understanding of the nature of the uranium-arene interaction. Density functional theory (DFT) shows the in- teraction energy reflects the interplay between higher energy electron rich π-systems which drive electrostatic contributions, and lower energy electron poor π-systems which give rise to larger or- bital contributions. The interaction is weak in all cases, which is consistent with the picture that emerges from a topological analysis of the electron density where metrics indicative of covalency show limited dependence on the nature of the ligand – the interaction is predominantly electro- static in nature. Complete active space natural orbital analyses reveal low occupancy U-arene π-bonding interactions dominate in all cases, while δ -bonding interactions are only found with high-symmetry and electron-rich C 6 Me 6 . Finally, both DFT and multireference calculations on a reduced congener, [U(C 6 Me 6 )(BH 4 ) 3 ] − – formally U(II), suggest the electronic structure (S = 1 or 2), and hence metal oxidation state, of such a species cannot be deduced from structural features such as arene distortion. Instead, we show the structure strongly depends upon the spin-state of the complex but that in both spin-states it is best described as U(III) and an arene-centred radical.
Optimizing Silver Nanowire Synthesis for Direct Ink Writing Applications: A Parametric Study
Authors: Cirit Elif Sümeyye , Akyuz Seda Aygul , Can Volkan , Canbek Ozdil Zeliha Cansu
Published: September 2023

This work presents a parametric study for optimizing the synthesis of silver nanowires (AgNWs) using a polyol method for conductive ink applications. The effects of various parameters, including reaction time, reaction temperature, and the type of metal halide employed during synthesis, on the properties of the AgNWs are systematically investigated. The kinetics of AgNW formation are analyzed by temporal UV-Vis spectroscopy and TEM. To elaborate on the complexity of the metal halide employed during the production of silver nanowires, we have conducted various sets of experiments revealing the role of the metal in classical polyol synthesis. We have demonstrated that even though the stoichiometric ratio of Ag+/Cl- is kept constant, the type of halide source is directly related to the formation of high-yield silver nanowires. The optimized synthesis conditions are found to result in AgNWs with high aspect ratios to prepare a conductive ink with desired viscoelastic properties for direct writing applications. The AgNW ink prepared with a 4 wt.% PEO mixture can automatically level itself at the specified frequency, while the 5 wt.% solution requires an external force to spread out. The frequency sweep experiments revealed that both mixtures have a crossover point where their behavior changes. The crossover point for the 4 wt.% mixture is approximately 12 rad/s, whereas for the 5 wt.% mixture, it is 2.5 rad/s. As a result, the 5 wt.% mixture takes longer to spread out than the 4 wt.% mixture.
RISK FINANCING TECHNIQUES AND SAFETY CULTURE OF ROAD CONSTRUCTION COMPANIES IN EKITI STATE, NIGERIA.
Authors: Oluwaleye Taiwo Olarinre , ADULOJU Sunday Adekunle
Published: September 2023

This study explores the effects of risk financing techniques on the safety culture among selected road construction companies in Ado-Ekiti, Nigeria. The study engaged a descriptive survey research design. The population of the study comprises all twenty-eight (28) indigenous road construction companies in Ekiti State out of which seven road construction companies were purposively chosen for the study. A total of 130 copies of a structured questionnaire were dispersed among the respondents to gather data for this study, out of which 118 which represent a 90.6% response rate was found useful for analysis. Descriptive and inferential statistics were used for data analysis. The regression results from the structural equation model revealed that Risk retention has a significant influence on the safety culture with estimates .143(P= .015< .05) while the risk transfer technique recorded an estimate -.002(P=.987>.05) indicating a negative insignificant relationship with the safety culture of road construction companies in Ekiti State, Nigeria. Finally, this study confirms that risk financing techniques hold a negative significant joint influence on the safety culture of road construction companies in the metropolis of Ado, Ekiti State based on reported estimates -.591and (P =***< .05). Therefore, the researcher recommends that road contractors should be meticulous about the appropriate risk financing techniques that will aid safety culture.
EVALUATING TURNAROUND STRATEGIES AND ORGANIZATIONAL PERFORMANCE IN A SMALL BUSINESS–A STUDY OF EKO SUPPORT SERVICE LIMITED.
Authors: AJEMUNIGBOHUN Sunday Stephen
Published: September 2023

Numerous associations today experience authoritative decay sooner or later in their life cycles as a result of both outside and inside factors. Much of the time, associations face decline when they neglect to perceive and adjust to outer and interior tensions that compromise the association's presence. The reaction to such circumstances is quite often a significant amount of work to "turn the organization around". This study seeks to examine the effects of turnaround strategies on organizational performance of Eko Support Service Limited. The researcher used a structured questionnaire to collect data. The population of the study was 400 and a sample of 200 respondents was obtained via the Taro Yamane formula. The data collected were analyzed using descriptive statistics such as simple percentages and the relationship between the variables of the model was tested using linear regression analysis. The study found that there is a positive and significant effect of diversification strategy on market share (R2 = 0.127, at p<0.05) and the F-Value yielded 9.335. The result of hypothesis 2 also indicates a positive significant effect of retrenchment strategy on profitability (R2 = 0.388, at p<0.05) and F-Value yielded 60.793 and lastly, top management re-organization strategy has a significant effect on organizational efficiency (R2 = 0.116, at p<0.05) and F-Value yielded 13.034. The study, therefore, concludes top-level management have significant roles to play indecision-making and conceptual skill regarding turnaround strategies and their applicability. The study recommends that top management re-organization in terms of structure, people, leadership, and organizational culture should be given priority in times of distress as this has proven to be a measure to improve organization efficiency.
Algorithm contest of motor imagery BCI in the World Robot Contest 2022: A survey
Authors: An Jiayu , Chen Xinru , Wu Dongrui
Published: September 2023

From August 19 to 21, 2022, the BCI Controlled Robot Contest finals in the World Robot Contest 2022 were held in Beijing, China. Fifteen teams participated in the finals in the Algorithm Contest of Motor Imagery BCI. This paper introduces the algorithms in the motor imagery (MI) classification area, describes the competition content and set, and summarizes the algorithms and results of the top five teams in the finals.

First, the MI paradigm and the overview of the existing motor imagery brain–computer interface classification algorithms are introduced, followed by the introduction of the algorithms of the top five teams in the final step by step, including electroencephalography channel selection, data length selection, data preprocessing, data augmentation, classification network, training, and testing settings. Finally, the highlights and results of each algorithm are discussed.
Visita de Estado de D. Manuel II a França (1909): o discurso da Ilustração Portuguesa
Authors: Sousa Jorge Pedro , Guimaraes-Guedes Denise
Published: September 2023

O rei português, Manuel II, visitou, oficialmente, França, entre 27 de novembro e 2 de dezembro de 1909. Esta pesquisa analisa a narrativa iconográfica – contando com o correspondente texto verbal – que a revista ilustrada semanal Ilustração Portuguesa, de Portugal, construiu do acontecimento. Utiliza-se uma metodologia qualiquantitativa. A componente qualitativa baseia-se numa abordagem hermenêutica e heurística ao discurso, com os objetivos de identificar as estruturas de linguagem iconoverbal e narrativas em jogo e de desvelar os enquadramentos propostos ao leitor, tendo em consideração o que se conhece sobre o contexto histórico da época e a noticiabilidade do acontecimento. A componente quantitativa baseia-se numa análise de conteúdo com categorias definidas a priori. Concluiu-se que a cobertura jornalística ofereceu uma leitura fílmica e testemunhal da evolução do acontecimento, valorizou a imagem do soberano português, recebido com honras numa república, e sustentou, assim, simbolicamente, o statu quo, beneficiando a monarquia portuguesa.
A formação histórica e territorial da Rádio Educadora Rio Doce em Governador Valadares-MG (1950-1960)
Authors: Genovez Patrícia Falco , Alves Denise Rodrigues
Published: September 2023

O artigo versa sobre a formação histórica e territorial do primeiro veículo de radiodifusão sonora de Governador Valadares-MG, a Rádio Educadora Rio Doce, entre 1950 e 1960. Trata-se de um estudo interdisciplinar – por contemplar uma abordagem territorial da Geografia da Comunicação – e inédito, considerando-se que não há estudos sobre a rádio e toda a sua documentação encontra-se dispersa. Optou-se por uma pesquisa qualitativa, guiada pela História Oral. A abordagem narrativa foi adotada para a análise com o intuito de refletir a respeito dos sujeitos envolvidos no surgimento e consolidação da rádio e de suas interações na constituição de uma territorialização efetiva da Rádio Educadora Rio Doce. Como resultado, compreendeu-se que os participantes consolidaram uma narrativa da emissora articulada ao ideal de progresso e de modernidade, mobilizando a população local em vários contextos, tornando-se uma referência na defesa dos interesses da cidade, apesar da censura, perseguição de alguns radialistas e de ter sido fechada em uma ocasião, por razões políticas locais.
Um modelo híbrido de comunicação institucional? O caso de Lençóis Paulista-SP
Authors: Bazo Junior Rafael , Pieranti Octavio Penna
Published: September 2023

Apesar de a Constituição Federal de 1988 prever três sistemas de radiodifusão autônomos e complementares – o público, o privado e estatal – e de existirem regras específicas para serviços que poderiam ser identificados com esses sistemas, surgiram, em diversos municípios, modelos híbridos. O objetivo deste artigo é oferecer uma abordagem histórica da comunicação institucional de governo, em Lençóis Paulista, São Paulo, pela Rádio Difusora, localizando-a em um contexto de hibridismo dos sistemas de radiodifusão, a partir de uma análise bibliográfica e documental. São apresentados os vínculos históricos da emissora com o poder público e os programas institucionais por ela produzidos e transmitidos, visto que é contratada pelos poderes Executivo e Legislativo locais, bem como são apontadas algumas fragilidades desse formato. Questiona-se se a emissora pode realizar um jornalismo crítico, ancorado na fiscalização do Poder Público, se ele é um dos financiadores diretos da programação.
Discussão sobre as características descolonizadoras da folkcomunicação: comunicar e conhecer na Feira Central de Campina Grande (PB)
Authors: Silva Freire Ermaela Cícera
Published: September 2023

As práticas culturais e comunicacionais das populações marginalizadas continuam coexistindo com as inovações tecnológicas próprias da globalização, isso demonstra a capacidade de resistência e ressignificação cultural dos agentes da cultura popular. O objetivo desse trabalho é discutir as características folkcomunicacionais e descolonizadoras no universo da Feira Central de Campina Grande (PB). Metodologicamente, realizamos uma pesquisa bibliográfica, a partir do arcabouço teórico a seguir: Kilomba (2008), Beltrão (2014), Marques de Melo (2008 e 2010), Santos e Meneses (2013), Santos  (2019) e  Mignolo (2016). Concluimos que a utilização desse caminho teórico auxilia na compreensão dos fenômenos sociais, culturais e comunicacionais e ainda evidenciam a força da tradição popular expressa nas narrativas, nos saberes, nas vivências e nos processos de sociabilidade próprios da cultura popular ou subalterna. Foi possível ainda observarmos algumas narrativas folkcomunicacionais e por sua vez contra hegemônicas que permeiam a Feira Central de Campina Grande (PB), dessa forma percebemos que a descolonização epistêmica é uma alternativa para as investigações científicas da comunicação popular.
PENGARUH TEMPERATUR ROASTING BIJI KOPI TERHADAP KANDUNGAN KAFEIN MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS
Authors: Nur rizky Andri , Muarif Agam , Bahri Syamsul , Sylvia Novi , Kurniawan Eddy , Fibarzi Wiza Ulfa
Published: September 2023

Proses Roasting adalah proses pembentukan rasa dan aroma pada biji kopi. Apabila biji kopi memiliki keseragaman dalam ukuran, specific grafity, tekstur, kadar air dan struktur kimia, maka proses penyangraian akan relatif lebih mudah untuk dikendalikan. Penelitian ini dilakukan untuk memberikan informasi kepada masyarakat tentang kadar kafein dalam kopi yang diroasting dengan variasi temperatur tertentu. Rancangan penelitian yang digunakan adalah Rancangan Acak Lengkap (RAL) Faktorial dengan perlakuan variasi temperatur dan Jenis biji kopi, temperatur roasting terdiri dari suhu 195°C, 205°C, dan 215°C sedangkan biji kopi terdiri dari biji kopi jenis Arabika dan Robusta yang diambil dari kecamatan Timang gajah kabupaten Bener meriah provinsi Aceh. Hasil analisis sidik ragam (ANOVA) menunjukkan bahwa variasi temperatur dan jenis biji kopi berpengaruh sangat nyata terhadap kadar air dan kadar kafein. Perlakuan roasting biji kopi Arabika pada temperatur tertinggi yaitu 2150C Menghasilkan kadar kafein sebesar 15,43788 ppm dan kadar air sebesar 1,42%, sedangkan untuk temperatur terendah yaitu 1950C menghasilkan kadar kafein sebesar 12,07424 ppm dan kadar air sebesar 2,59 %. dan Perlakuan roasting biji kopi Robusta pada temperatur tertinggi yaitu 2150C Menghasilkan kadar kafein sebesar 22,92273 ppm dan kadar air sebesar 3,9 % sedangkan untuk temperatur terendah yaitu 1950C menghasilkan kadar kafein sebesar 18,24091 ppm dan kadar air sebesar 6,58%. Semakin tinggi temperatur maka semakin gelap warna kopi hasil roasting. Pengujian kadar kafein dalam kopi dilakukan dengan metode Spektrofotometri UV-Vis pada panjang gelombang 275 nm. Berdasarkan uji organoleptik kopi Arabika yang paling disukai panelis adalah kopi yang diroasting pada suhu 205˚C, sedangkan kopi Robusta yang paling disukai oleh panelis adalah kopi yang diroasting pada suhu 205°C.Kata kunci:Biji kopi Arabika, Biji kopi Robusta, Roasting, Temperatur, Uv - Vis