bluuebunny/crossref_metadata_2025 huggingface dataset:
Blast Wave Simulator for Laminated Glass Panels Experimental Evaluation
Authors: Nawar Mahmoud T. , El-Zohairy Ayman , El-Sisi Alaa , Salim Hani , Aldoshan Abdelhakim A.
Published: July 2024

The study of blast loads on structures is important due to the potential of significant consequences in various scenarios. From terrorist attacks to industrial accidents, comprehending how structures respond to blast waves is critical for ensuring public safety and designing resilient structures. Studying these effects typically involves two main methods: free-field tests with live explosives and shock tube tests. Although shock tube testing offers certain advantages, both approaches are costly and demand significant space. This research aims to develop a cost-effective and straightforward technique for generating stress waves that closely replicate the progressive and spatial characteristics of free-field or shock tube blast waves. This method was designed to evaluate the dynamic response of laminated glass panels. The stress wave was generated by impacting a piston on the fluid inside a tube, which was connected to a fluid chamber. This setup produced impulsive loads that were distributed across a laminated glass test panel. Moreover, it was used to simulate the shock near filed explosions for a certain part of a structure. High-speed cameras were utilized to analyze the initial velocity of flying glass fragments. The apparatus successfully produced various blast waves and impulsive profiles for different drop weight heights. The initial velocities of randomly selected flying shards ranged from 3 m/s to 4 m/s.
Application of Thermal Spraying Technology in Concrete Surface Ceramic-Based Coating
Authors: Shi Yan , Wang Yupu , Lv Xingdong , Jiang Wenguang , Wu Cai
Published: July 2024

Enhancing the durability and extending the service life of concrete are crucial for promoting its sustainable development. Applying surface coatings is the primary technical method used to improve concrete durability. In this study, based on the plasma thermal spraying technology, a thermal-sprayed, ceramic-based coating was prepared on a concrete surface and evaluated using the drawing method, X-ray diffraction scanning electron microscopy with energy dispersive spectroscopy, X-ray computed tomography (X-CT), and frictional wear. Subsequently, performance tests were conducted. The test results showed that mullite powder was a suitable ceramic-based coating material. The coating had a good interfacial bonding ability with the concrete surface; moreover, the bonding site exhibited a chimeric state with an adhesion strength of 3.82 MPa. The wear rate of the coating material (0.02‰) is lower than that of the concrete matrix (0.06‰), resulting in improved surface wear resistance. SEM analysis reveals that the coating contains a considerable amount of amorphous or microcrystalline phases. The internal structure of the coating exhibits porous characteristics, with a total porosity of 10.35% and pore diameters predominantly ranging from 4 μm to 16 μm. At a distance of 80 μm from the coating site, the elements Al, O, and Si significantly contribute to the mullite components. The porous structures within the coating products are further verified using X-CT. This study offers a new possibility for ceramic coatings on hydraulic concrete.
The Study of Combination of Biodegradable Packaging and Biocoating with Lactic Acid Bacteria as a Green Alternative for Traditional Packaging in Gouda Cheese
Authors: Aleksandrovas Elvidas , Vasiliauskaitė Agnė , Milerienė Justina , Muizniece-Brasava Sandra , Ciprovica Inga , Songisepp Epp , Rud Ida , Axelsson Lars , Kasparavičienė Beatričė , Lutter Liis , Malakauskas Mindaugas , Šernienė Loreta
Published: July 2024

Biodegradable packaging, both alone and in combination with acid whey protein coatings, has been used to pack fresh Gouda cheese to improve preservation prior ripening or storage. This study involved three key components: (i) the selection of biodegradable packaging (BP), (ii) the development of a plain liquid acid whey protein concentrate, pectin-based edible coating (BP + Ch + Coating), and (iii) the incorporation of at least 6 log10 CFU (colony forming units) mL−1 Lacticaseibacillus paracasei (BP + Ch + Coating + Lp) and Lactobacillus helveticus (BP + Ch + Coating + Lh) strains. The created compositions were compared with cheese packed in conventional polyethylene (PE) packaging to evaluate their overall synergy effect in reducing microbiological spoilage and influencing chemical parameters in Gouda cheese during 45 days of ripening and cold storage. The evaluation included microbiological analysis (total LAB, Enterobacteriaceae spp., and fungi CFU) and quality assessment of pH, moisture content, water activity, texture, and colour (CEI system) during ripening and shelf life. Although biodegradable packaging (BP) alone did not protect the cheese effectively compared to conventional packaging (EVA/PE/EPC/PVDC), the combination of biodegradable packaging with a coating (BP + Ch + Coating) showed protective properties against Enterobacteriaceae spp. and mould, maintaining moisture, pH, and colour during ripening and storage. Incorporation of L. helveticus (BP + Ch + Coating + Lh) into the coating efficiently decreased the growth of fungi.
Synthesis and Characterization of Multifunctional Symmetrical Squaraine Dyes for Molecular Photovoltaics by Terminal Alkyl Chain Modifications
Authors: Mori Kota , Kurokawa Yuki , Pandey Shyam S.
Published: July 2024

Novel far-red sensitive symmetric squaraine (SQ) dyes with terminal alkyl chain modifications were designed, synthesized, and characterized, aiming towards imparting multifunctionalities such as photosensitization, dye aggregation prevention, and source of electrolyte components. The dye sensitizer SQ-80 with alkyl chain terminal modifications consisting of 1-methylimidazolium iodide was designed and synthesized as a new dye sensitizer for DSSCs based on symmetric SQ-4 without any terminal modification used as reference. Upon adsorption on the mesoporous TiO2 surface, SQ-80 demonstrated reduced dye aggregation and stronger binding to the TiO2 surface, leading to enhanced durability of DSSCs. Apart from the most common photosensitization behavior, the newly designed dye demonstrated multifunctionalities such as aggregation prevention and electrolyte functionality, utilizing iodine-based redox electrolytes in the presence and absence of I2 and LiI additives. In the absence of LiI and I2, a mixture of SQ-77 with alkyl chain terminal modifications consisting of iodide and SQ-80 demonstrated a photoconversion efficiency of 1.54% under simulated solar irradiation, which was about six times higher compared with the reference dye SQ-4 (0.24%) (having no alkyl chain terminal modification).
A Comprehensive Review of Processing-in-Memory Architectures for Deep Neural Networks
Authors: Kaur Rupinder , Asad Arghavan , Mohammadi Farah
Published: July 2024

This comprehensive review explores the advancements in processing-in-memory (PIM) techniques and chiplet-based architectures for deep neural networks (DNNs). It addresses the challenges of monolithic chip architectures and highlights the benefits of chiplet-based designs in terms of scalability and flexibility. This review emphasizes dataflow-awareness, communication optimization, and thermal considerations in PIM-enabled manycore architectures. It discusses tailored dataflow requirements for different machine learning workloads and presents a heterogeneous PIM system for energy-efficient neural network training. Additionally, it explores thermally efficient dataflow-aware monolithic 3D (M3D) NoC architectures for accelerating CNN inferencing. Overall, this review provides valuable insights into the development and evaluation of chiplet and PIM architectures, emphasizing improved performance, energy efficiency, and inference accuracy in deep learning applications.
An Analysis of Protein Crystals Grown under Microgravity Conditions
Authors: Jackson Keegan , Hoff Rebecca , Wright Hannah , Wilkinson Ashley , Brewer Frances , Williams Amari , Whiteside Ben , Macbeth Mark R. , Wilson Anne M.
Published: July 2024

Microgravity has been shown to be an excellent tool for protein crystal formation. A retrospective analysis of all publicly available crystallization data, including many that have not yet been published, clearly demonstrates the value of the microgravity environment for producing superior protein crystals. The parameters in the database (the Butler Microgravity Protein Crystal Database, BμCDB) that were evaluated pertain to both crystal morphology and diffraction quality. Success metrics were determined as improvements in size, definition, uniformity, mosaicity, diffraction quality, resolution limits, and B factor. The proteins in the databases were evaluated by molecular weight, protein type, the number of subunits, space group, and Mattew’s Coefficient. Compared to ground experiments, crystals grown in a microgravity environment continue to show improvement across all metrics evaluated. General trends as well as numerical differences are included in the assessment of the BμCDB. The microgravity environment improves crystal formation across a spectrum of metrics and the datasets utilized for this investigation are excellent tools for this evaluation.
TRPS1 Expression Is Frequently Seen in a Subset of Cutaneous Mesenchymal Neoplasms and Tumors of Uncertain Differentiation: A Potential Diagnostic Pitfall
Authors: Kim Moon Joo , Liu Yi A. , Wang Yunyi , Ning Jing , Cho Woo Cheal
Published: July 2024

Although extensively studied in cutaneous epithelial neoplasms, the TRPS1 immunoreactivity in cutaneous mesenchymal neoplasms and tumors of uncertain differentiation (CMNTUDs), such as atypical fibroxanthoma (AFX), remains largely unexplored. We assessed TRPS1 immunoreactivity in 135 CMNTUDs, comprising 46 fibrohistiocytic/fibroblastic tumors, 28 vascular tumors, 24 peripheral nerve sheath tumors (PNSTs), 21 tumors of uncertain differentiation, and 16 smooth muscle tumors. Additionally, we included selected cases of melanoma with spindled cell morphology or desmoplastic features (n = 9) and sarcomatoid squamous cell carcinoma (SSCC) (n = 5) to compare TRPS1 expression patterns with those of AFX. TRPS1 expression was prevalent in dermatofibromas (24/24), leiomyomas (8/8), AFXs/pleomorphic dermal sarcoma (PDS) (20/21), dermatofibrosarcomas protuberans (14/22), and leiomyosarcomas (6/8). It was uncommon in angiosarcomas (3/20), Kaposi sarcomas (2/8), and neurofibromas (5/17) and absent in perineuriomas (0/2). AFXs/PDS exhibited the highest median H-score of 240, contrasting with minimal TRPS1 immunoreactivity in vascular neoplasms and PNSTs, with median H-scores consistently below 10. Significant differences in H-score were observed between AFXs/PDS and angiosarcomas (p < 0.001), melanomas (p < 0.001), and leiomyosarcomas (p = 0.029). However, no significant difference was found compared to SSCCs, suggesting limited discriminatory power of TRPS1 in this context. This study sheds light on TRPS1 expression patterns in a subset of CMNTUDs, extending beyond prior studies primarily focused on epithelial tumors, while underscoring potential pitfalls associated with TRPS1 immunohistochemistry.
A Comprehensive Multidisciplinary Approach to Diagnosing Chronic Inflammatory Bowel Diseases: Integration of Clinical, Endoscopic, and Imaging Modalities
Authors: Cicerone Clelia , D’Amico Ferdinando , Allocca Mariangela , Zilli Alessandra , Parigi Tommaso Lorenzo , Danese Silvio , Furfaro Federica
Published: July 2024

Chronic inflammatory bowel diseases, such as Crohn’s disease and ulcerative colitis, present diagnostic challenges due to their complex and heterogeneous nature. While histology remains fundamental for accurate diagnosis, a multidisciplinary approach incorporating clinical, endoscopic, and imaging modalities is increasingly recognized as essential for comprehensive evaluation. This article delves into the importance of integrating various diagnostic techniques in the assessment of IBD. Colonoscopy and histology, with its ability to directly visualize the intestinal mucosa, play a central role in the diagnostic process. However, histological analysis alone may not suffice, necessitating the inclusion of advanced imaging techniques, such as magnetic resonance enterography (MRE), computed tomography enterography (CTE), and intestinal ultrasound (IUS). These techniques provide valuable insights into the disease’s extent, severity, and complications, and should be used in conjunction with biochemical parameters. These modalities complement traditional endoscopic and histological findings, offering a more holistic understanding of the disease process. A multidisciplinary approach that incorporates clinical, endoscopic, histological, serological, and imaging assessments enables clinicians to achieve a more accurate and timely diagnosis of IBD. Moreover, this integrated approach facilitates personalized treatment strategies tailored to individual patient needs, ultimately improving clinical outcomes and quality of life for those affected by chronic inflammatory bowel diseases.
Monitoring the Mineral Content of Plant Foods in Food Composition Databases
Authors: Jenkins Amanda , Murthy Diva , Rangan Anna
Published: July 2024

Declines in the mineral content of food have been reported in several countries. This study monitored reported changes in the mineral content of plant foods in Australian food composition databases between 1991 and 2022. Commonly consumed plant foods (n = 130), grouped as fruit, vegetables, legumes, grains, and nuts in raw unprocessed form, were matched between three reference databases from 1991, 2010, and 2022. Absolute and percentage differences in mineral content (iron, zinc, calcium, and magnesium) were calculated. During this 30-year period, 62 matched foods had updated mineral content. Iron content decreased significantly for fruit (48%) and vegetables (20%), although absolute differences were small (0.09–0.14 mg/100 g). Zinc content declined by 15% for fruit (absolute difference 0.03 mg/100 g), but no differences were observed for calcium and magnesium content. Potential reasons for any reported differences could not be explored using food composition data alone, due to biological, agricultural, and/or analytical factors. Nutritionally, these small differences are unlikely to have a major impact on the population’s nutritional status, although efforts to improve fruit and vegetable consumption are encouraged to meet recommendations.
Control of Helicopter Using Virtual Swashplate
Authors: Flores Jonathan , Salazar Sergio , Gonzalez-Hernandez Ivan , Rosales Yukio , Lozano Rogelio , Salazar Eduardo , Nicolas Benjamin
Published: July 2024

This article presents a virtual swashplate mechanism for a mini helicopter in classic configuration. The propeller bases are part of a passive mechanism driven by main rotor torque modulaton, this mechanism generates a synchronous and opposite change in the propellers angle of attack, then the thrust vector tilts. This approach proposes to control the 6 degrees of freedom of the aircraft using two rotors. The main rotor controls vertical displacement and uses torque modulation and swing-hinged propellers to generate pitch and roll moments and the horizontal displacement while the yaw moment is controlled by the tail rotor. The dynamic model is obtained using the Newton-Euler approach and robust control algorithms are proposed. Experimental results are presented to show the performance of the proposed virtual swashplate in real-time outdoor hover flights.
Influence of Processing Parameters on Laser-Assisted Reactive Sintering of a Mixture of Ni and Ti Powders
Authors: Le Sénéchal Naiara Vieira , da Silveira Pedro Henrique Poubel Mendonça , Rodrigues Patrícia Freitas , Gonçalves Danilo Abílio Corrêa , Dyer Silvelene Alessandra Silva , Teixeira Rodolfo da Silva , de Siqueira Rafael Humberto Mota , de Lima Milton Sergio Fernandes , Bayerlein Daniel Leal , Paula Andersan dos Santos
Published: July 2024

Additive manufacturing (AM) plays a crucial role in the development of NiTi alloys, enabling the creation of complex and customized structures while optimizing properties for various biomedical and industrial applications. The aim of this paper was to investigate the influence of laser scanning speed on laser-assisted reactive sintering of a mixture of No and Ti powders. The samples were sintered at two different beam speeds, 4 and 5 4 mm/s and their morphological and microstructural characteristics were investigated. Scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDX) and X-ray diffraction (XRD) analyses revealed the presence of intermetallic compounds rich in Ni and Ti for both scanning speeds; however, the scanning speed of 5 mm/s produced a microstructure with greater porosity, leading to a sintered body with poorer consolidation. Thus, employing a slower beam scanning of 4 mm/s seems to be a better alternative in the laser-assisted reactive sintering of NiTi alloys.
Repeated Mild Summer Drought in Crataegus monogyna Jacq. Provokes Compensation Growth in the Following Year
Authors: Mijnsbrugge Kristine Vander , Moreels Stefaan , Decorte Laura , Stessens Marie , Notivol Paino Eduardo
Published: July 2024

Water limitations will pose significant challenges to forest ecosystems across Europe. To gain a deeper understanding of the potential impacts, we investigated the response of the common shrub Crataegus monogyna to two summer droughts, each followed by rewatering. The experimental design consisted of a common garden with potted saplings from a local Belgian (n = 48), a Swedish (n = 47), and a Spanish-Pyrenean provenance (n = 48). We quantified the effects on growth and leaf phenology, focusing on the legacies in the year following the droughts. Responses were influenced by the severity of the drought and by its timing. Most strikingly, height increment was enhanced by 24% (p = 0.046) in comparison to the controls in the year following the droughts in the group of plants that endured the two drought treatments, each time without developing visible stress symptoms. Only one such mild drought, whether early or late summer, did not lead to this response, suggesting stress memory acting as a growth promoter. A late summer drought that resulted in visible drought symptoms led to a reduced diameter increment in the year following the droughts, independent of the preceding treatment (severe, mild, or no drought), whereas this was not the case for a similar drought in early summer. Minor leaf phenological responses were detected in the year following the droughts. Finally, the non-local provenances did not respond in a deviating way to the droughts compared to the local provenance. Our findings contribute to the prediction of carbon sequestration in forests and other woody vegetations in the temperate regions of Europe.
An Index System for the Evaluation of the Effectiveness of Forest Ecological Product Value Realization in China
Authors: Xie Xiansheng , Chen Shaozhi , Zhao Rong
Published: July 2024

Forest Ecological Product Value Realization (FEPVR) is an important way for China to promote the transition and development of forestry and realize common prosperity. It is critical to assess the effectiveness of FEPVR rationally to obtain a comprehensive understanding of the progress of ecological civilization. Based on the Driver–Pressure–State–Impact–Response (DPSIR) model, in this study, we developed an evaluation index system for FEPVR effectiveness containing five subsystems and 37 indicators and assessed the effectiveness of FEPVR in China from 2011 to 2022 by using the linear weighted sum method, the coupling degree of coordination model, and Spearman’s correlation analysis. The results showed that the composite index increased from 0.1980 in 2011 to 0.6501 in 2022, with a general upward trend, but there is still great potential for improvement. The main contribution was from the Response subsystem. The year 2017 was an important turning point for FEPVR in China because its development started to speed up; the status of coupling coordination between different subsystems was gradually improving but was still at a low level. The relationship between all indicators was dominated by a non-significant correlation (52.4%), and the overall synergistic effect (27.8%) was greater than the trade-off effect (19.8%). This study provides a new perspective for evaluating the effectiveness of FEPVR and a decision-making reference for clarifying the direction of FEPVR optimization.
Spatial Distribution Patterns and Influencing Factors of Dominant Species in Plain Valley Forests of the Irtysh River Basin
Authors: Song Jihu , Xue Zhifang , Yang Bin , Liu Tong , Yuan Ye , Xu Ling , Zhang Zidong
Published: July 2024

The Irtysh River, which stretches for 633 km, is the second longest river in Xinjiang. The valley forests within its basin are unique forest resources that exhibit crucial ecological functions and form an integral part of China’s “Three North” Shelterbelt Forest Project. However, previous studies mainly focused on individual tributaries or main streams, lacking comprehensive research on the overall river and valley forest resources and their ecological functions. To address this research gap based on comprehensive investigations, this study analyzed the dominant species composition, spatial distribution patterns, and influencing factors of valley forests across various branches of the Irtysh River basin plain. The results revealed the presence of 10 local tree species in the area, with Populus laurifolia, Populus alba, Salix alba, and Betula pendula as the dominant species. However, seedling regeneration was relatively weak. P. laurifolia, P. alba, and S. alba were widely distributed across tributaries and main streams, whereas B. pendula was primarily found in the tributaries. The four dominant species exhibited distinct clustering patterns. The concentration intensity of these dominant species in the main stream of the Irtysh River basin was significantly higher than those in other tributaries, with P. laurifolia showing a lower concentration intensity across the entire basin than the other dominant species. Negative density dependence was the primary biological factor influencing species aggregation intensity, with significant positive effects on P. alba and S. alba and significant negative effects on B. pendula. Among the abiotic factors, elevation had a significant positive effect on the aggregation intensities of P. alba, S. alba, and B. pendula, indicating that these species tend to aggregate more densely at higher elevations. Conversely, slope had a significant negative impact on the aggregation intensities of P. laurifolia, P. alba, and S. alba, suggesting that increasing slope steepness leads to a decrease in the clustering of these species. Similarly, the distance from the river channel had a significant negative effect on the aggregation intensities of S. alba and B. pendula, implying that as the distance from the river increases, the clustering patterns of these species become less pronounced. This study aimed to detail the current state of valley forest resources and their ecological functions, thereby laying a foundation for their effective protection.
Remark: Evaluation of the Habitat and Potential of Taxus chinensis var. mairei in the Jiangnan Hilly Region
Authors: Bao Ruyi , Liu Jiufen , Liu Xiaohuang , Zhao Xiaofeng , Xia Xueqi , Wang Chao
Published: July 2024

Taxus chinensis var. mairei is an endangered tree species endemic to China; it has important ornamental, timber, and medicinal value. In this work, based on a MaxEnt model, the Jiangnan hilly region was used as the study area, and geographic, climatic, soil, and vegetation data were synthesized to simulate the present area of suitable habitat for T. chinensis; the key environmental factors that constrain its habitat expansion were also explored. Additionally, the potential future distribution of this species under different climate-change scenarios was predicted. The results showed that the six variables making the highest contribution to T. chinensis habitat suitability were the precipitation of the warmest quarter (14.2%), precipitation seasonality variation coefficient (9.1%), aspect (8.2%), altitude (8%), maximum temperature of the warmest month (7.4%), and base saturation (6.6%). Ideal areas have middle elevations, northeastern or northwestern slopes, warmest quarterly precipitation of 508.3–629.2 mm, maximum temperature in the warmest month of 34.6–35.9 °C, and relatively moist soil. The current area of suitable habitat is 6.09 × 105 km2, of which the area of high suitability is 7.56 × 104 km2; this is mainly concentrated in the southwestern part of Hunan, the southwestern part of Jiangxi Province, and the northern part of Zhejiang. Under the SSP2-4.5 climate scenario, the area of high habitat suitability increases; under both the SSP1-2.6 and SSP5-8.5 climate scenarios, the suitable habitat area expands similarly. The direction of the center-of-mass migration of T. chinensis under different climate scenarios is somewhat different from that caused by the uncertainty of human activities and climate warming. This paper clarifies the distribution of suitable habitat and future potential for T. chinensis in the Jiangnan hilly region, providing a theoretical basis for habitat management of this species.
Cenostigma pluviosum Tree Stem Growth and Carbon Storage in a Subtropical Urban Environment: A Case Study in Sao Paulo City
Authors: Rodrigues-Leite Julia , Duarte Denise , Moser-Reischl Astrid , Rötzer Thomas
Published: July 2024

Our aim is to contribute to understanding the role of subtropical trees on carbon storage and CO2 removal in the city of Sao Paulo/Brazil, besides highlighting the surrounding environment implications to sibipiruna trees (Cenostigma pluviosum)’s performance. The case study was conducted with three trees, one planted on a sidewalk in Pinheiros neighborhood, a highly sealed area, and two in a green area, the Ibirapuera Park. To define the stem basal area growth and its pattern, local measurements were taken over a year and a segmented linear regression model was adjusted. The stem growth dependency on microclimate was tested by a Spearman Correlation. The trees’ active stem growth presented a similar pattern. The soil volumetric water content and soil temperatures were the variables with more impact. The total mean radial stem growth for the IBIRA1 and IBIRA2 trees was 1.2 mm year−1 and 3 mm year−1, while at PIN1 it was 1.3 mm year−1. The total biomass increment in IBIRA1 and IBIRA2 was 4.2 kg C year−1 and 12.8 kg C year−1, while in PIN it was 4.9 kg C year−1 and the removal was 15.3 C year−1, 47.1 kg CO2 year−1 and 17.9 kg CO2 year−1, respectively. The results indicated that the land cover difference implies a significant interference with the promotion of carbon fixation and CO2 removal, demonstrating that planting urban trees in soils with better water storage conditions is more efficient.
From Proliferation to Protection: Immunohistochemical Profiling of Cardiomyocytes and Immune Cells in Molly Fish Hearts
Authors: Zaccone Giacomo , Mokhtar Doaa M. , Alesci Alessio , Capillo Gioele , Albano Marco , Hussein Manal T. , Aragona Marialuisa , Germanà Antonino , Lauriano Eugenia R. , Sayed Ramy K. A.
Published: July 2024

Unlike adult mammalian cardiomyocytes, cardiomyocytes in teleosts display high proliferative capacity throughout adulthood. This study aimed to identify the immunohistochemical profiles of cardiomyocytes and immune cells in the hearts of Molly fish by assessing the immunolabelling expression of key proteins involved in cell proliferation, differentiation, and tissue protection. The cardiac anatomy of Molly fish includes the atrium, ventricle, and bulbus arteriosus. The expression of SOX9, NF-κB, myostatin, and S100 proteins in myocardial cells indicates the proliferative features of the heart in Molly fish. The bulbus arteriosus is characterized by collagenous chambers and smooth muscle cells that express Ach and iba1. The atrium of Molly fish serves as a storage unit for rodlet cells and immune cells. Rodlet cells displayed immunoreactivity to NF-κB, iba1, Olig2, Ach, and S100 proteins, suggesting their roles in the immune response within the heart. Furthermore, telocytes (TCs) have emerged as a significant component of the atrium of Molly fish, expressing Ach, CD68, S100 protein, and iba1. These expressions indicate the involvement of TCs in multiple signaling pathways that contribute to heart architecture. This study delineates the intricate relationship between cardiomyocytes and innate immune cells in Molly fish.
Comprehensive Amelioration of Metabolic Dysfunction through Administration of Lactiplantibacillus plantarum APsulloc 331261 (GTB1™) in High-Fat-Diet-Fed Mice
Authors: Kim Bobae , Lee Yuri , Lee Chungho , Jung Eun Sung , Kang Hyeji , Holzapfel Wilhelm H.
Published: July 2024

The beneficial effects of probiotics for the improvement of metabolic disorders have been studied intensively; however, these effects are evident in a probiotic strain-specific and disease-specific manner. Thus, it is still essential to evaluate the efficacy of each strain against a target disease. Here, we present an anti-obese and anti-diabetic probiotic strain, Lactiplantibacillus plantarum APsulloc331261 (GTB1™), which was isolated from green tea and tested for safety previously. In high-fat-diet-induced obese mice, GTB1™ exerted multiple beneficial effects, including significant reductions in adiposity, glucose intolerance, and dyslipidemia, which were further supported by improvements in levels of circulating hormones and adipokines. Lipid metabolism in adipose tissues was restored through the activation of PPAR/PGC1α signaling by GTB1™ treatment, which was facilitated by intestinal microbiota composition changes and short-chain fatty acid production. Our findings provide evidence to suggest that GTB1™ is a potential candidate for probiotic supplementation for comprehensive improvement in metabolic disorders.
Development and Validation of a High-Performance Liquid Chromatography Diode Array Detector Method to Measure Seven Neonicotinoids in Wheat
Authors: Seccia Serenella , Albrizio Stefania , Morelli Elena , Dini Irene
Published: July 2024

Neonicotinoids (NEOs), used as insecticides against aphids, whiteflies, lepidopterans, and beetles, have numerous detrimental impacts on human health, including chronic illnesses, cancer, infertility, and birth anomalies. Monitoring the residues in food products is necessary to guarantee public health and ecological balance. The present work validated a new method to measure seven neonicotinoid insecticides (acetamiprid ACT, clothianidin CLT, dinotefuran DNT, imidacloprid IMD, nitenpyram NTP, thiacloprid TCP, and thiamethoxan THT) in wheat. The analytical procedure was based on simple and fast wheat sample cleanup using solid-phase extraction (SPE) to remove interferents and enrich the NEOs, alongside the NEOs’ separation and quantification by reverse-phase chromatography coupled with a diode array detector (DAD). The validation process was validated using the accuracy profile strategy, a straightforward decision tool based on the measure of the total error (bias plus standard deviation) of the method. Our results proved that, in the future, at least 95% of the results obtained with the proposed method would fall within the ±15% acceptance limits. The test’s cost-effectiveness, rapidity, and simplicity suggest its use for determining the levels of acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, and thiamethoxam in routine analyses of wheat.
Intelligent Food Packaging: Quaternary Ammonium Chitosan/Gelatin Blended Films Enriched with Blueberry Anthocyanin-Derived Cyanidin for Shrimp and Milk Freshness Monitoring
Authors: Chen Dan , Lv Jialiang , Wang Ao , Yong Huimin , Liu Jun
Published: July 2024

Blueberry anthocyanin-derived cyanidin (BAC) was used to prepare a series of responsive food freshness packaging films by compounding it with quaternary chitosan (QC) and gelatin (G). The fundamental properties, pH sensitivity, and functional attributes of the films were examined. The BAC solutions exhibited notable variations in color (from red to pink to violet) under different pH conditions. The incorporation of BAC resulted in improved UV–vis shielding capabilities but compromised the mechanical strength of the films (with tensile strength values from 85.02 to 44.89 MPa, elongation at break from 13.08% to 3.6%, and water vapor transmission rates from 5.24 × 10−9 to 7.80 × 10−9 g m−1 s−1 Pa−1). The QC-G-BAC films, containing 5–15 wt% BAC, exhibited noticeable color changes in acidic/ammonia environments within a short timeframe, easily discernible to the naked eye. Furthermore, the inclusion of BAC significantly enhanced the antioxidant and antimicrobial properties of the films. The addition of 5–15 wt% BAC to QC-G-BAC films could be employed for assessing the freshness of fresh shrimp (from red to dark red) and pasteurized milk (from red to dark earthy yellow). Among them, the total color difference (ΔE) of QC-G-BAC5 film was significantly correlated with the pH, acidity, and total colony count of pasteurized milk (R = 0.846, −0.930, −0.908, respectively). This new concept in smart packaging offers a straightforward and user-friendly freshness indicator.
Video and Audio Deepfake Datasets and Open Issues in Deepfake Technology: Being Ahead of the Curve
Authors: Akhtar Zahid , Pendyala Thanvi Lahari , Athmakuri Virinchi Sai
Published: July 2024

The revolutionary breakthroughs in Machine Learning (ML) and Artificial Intelligence (AI) are extensively being harnessed across a diverse range of domains, e.g., forensic science, healthcare, virtual assistants, cybersecurity, and robotics. On the flip side, they can also be exploited for negative purposes, like producing authentic-looking fake news that propagates misinformation and diminishes public trust. Deepfakes pertain to audio or visual multimedia contents that have been artificially synthesized or digitally modified through the application of deep neural networks. Deepfakes can be employed for benign purposes (e.g., refinement of face pictures for optimal magazine cover quality) or malicious intentions (e.g., superimposing faces onto explicit image/video to harm individuals producing fake audio recordings of public figures making inflammatory statements to damage their reputation). With mobile devices and user-friendly audio and visual editing tools at hand, even non-experts can effortlessly craft intricate deepfakes and digitally altered audio and facial features. This presents challenges to contemporary computer forensic tools and human examiners, including common individuals and digital forensic investigators. There is a perpetual battle between attackers armed with deepfake generators and defenders utilizing deepfake detectors. This paper first comprehensively reviews existing image, video, and audio deepfake databases with the aim of propelling next-generation deepfake detectors for enhanced accuracy, generalization, robustness, and explainability. Then, the paper delves deeply into open challenges and potential avenues for research in the audio and video deepfake generation and mitigation field. The aspiration for this article is to complement prior studies and assist newcomers, researchers, engineers, and practitioners in gaining a deeper understanding and in the development of innovative deepfake technologies.
Application of Fractional-Order Multi-Wing Chaotic System to Weak Signal Detection
Authors: Mao Hongcun , Feng Yuling , Wang Xiaoqian , Gao Chao , Yao Zhihai
Published: July 2024

This work investigates a fractional-order multi-wing chaotic system for detecting weak signals. The influence of the order of fractional calculus on chaotic systems’ dynamical behavior is examined using phase diagrams, bifurcation diagrams, and SE complexity diagrams. Then, the principles and methods for determining the frequencies and amplitudes of weak signals are examined utilizing fractional-order multi-wing chaotic systems. The findings indicate that the lowest order at which this kind of fractional-order multi-wing chaotic system appears chaotic is 2.625 at a=4, b=8, and c=1, and that this value decreases as the driving force increases. The four-wing and double-wing change dynamics phenomenon will manifest in a fractional-order chaotic system when the order exceeds the lowest order. This phenomenon can be utilized to detect weak signal amplitudes and frequencies because the system parameters control it. A detection array is built to determine the amplitude using the noise-resistant properties of both four-wing and double-wing chaotic states. Deep learning images are then used to identify the change in the array’s wing count, which can be used to determine the test signal’s amplitude. When frequencies detection is required, the MUSIC method estimates the frequencies using chaotic synchronization to transform the weak signal’s frequencies to the synchronization error’s frequencies. This solution adds to the contact between fractional-order calculus and chaos theory. It offers suggestions for practically implementing the chaotic weak signal detection theory in conjunction with deep learning.
On the Making of IXPE
Authors: Weisskopf Martin C. , Ramsey Brian
Published: July 2024

Drs. Weisskopf and Ramsey were the original Principal and Deputy Principal Investigators of the Imaging X-ray Polarimetry Explorer (IXPE). They outline the path to the development of IXPE and discuss the technical and programmatic history that led up to the mission, a partnership between the Italian Space Agency and NASA, and the first fully dedicated to imaging X-ray polarimetry in the 2–8 keV band. An admittedly biased, as seen through the eyes of the original and Deputy Principal Investigators, technical overview of the development of the historical and critical scientific instrumentation is provided. The outstanding, and often paradigm-shifting results are presented in the papers following this one.
Experimental Optimization of Natural Gas Injection Timing in a Dual-Fuel Marine Engine to Minimize GHG Emissions
Authors: De Simio Luigi , Marchitto Luca , Iannaccone Sabato , Pennino Vincenzo , Altieri Nunzio
Published: July 2024

Phased injection of natural gas into internal combustion marine engines is a promising solution for optimizing performance and reducing harmful emissions, particularly unburned methane, a potent greenhouse gas. This innovative practice distinguishes itself from continuous injection because it allows for more precise control of the combustion process with only a slight increase in system complexity. By synchronizing the injection of natural gas with the intake and exhaust valve opening and closing times while also considering the gas path in the manifolds, methane release into the atmosphere is significantly reduced, making a substantial contribution to efforts to address climate change. Moreover, phased injection improves the efficiency of marine engines, resulting in reduced overall fuel consumption, lower fuel costs, and increased ship autonomy. This technology was tested on a single-cylinder, large-bore, four-stroke research engine designed for marine applications, operating in dual-fuel mode with diesel and natural gas. Performance was compared with that of the conventional continuous feeding method. Evaluation of the effect on equivalent CO2 emissions indicates a potential reduction of up to approximately 20%. This reduction effectively brings greenhouse gas emissions below those of the diesel baseline case, especially when injection control is combined with supercharging control to optimize the air–fuel ratio. In this context, the boost pressure in DF was reduced from 3 to 1.5 bar compared with the FD case.
Exploring the Experience of Patients Who Received Mechanical Ventilation Support during Their Intensive Care Unit Stay
Authors: Zeadnih Ruba , Aljarrah Imad , Al-Qaaneh Ayman M. , Atout Maha
Published: July 2024

Objective: The objective of this study is to explore the experiences of patients who received mechanical ventilation (MV) support during their intensive care unit (ICU) stay in Jordan. Methods: A phenomenological hermeneutic approach was conducted, informed by the philosophy of Martin Heidegger. Fifteen patients participated in interviews regarding their experiences during their time in the critical care unit of three public hospitals in Jordan. Interpretive Phenomenological Analysis (IPA) was used to analyse the data. Findings: The findings of the current study indicated that patients who received MV support during their ICU stays experienced both physical and psychological suffering. A pattern of shared experiences among intensive care patients was identified. Five main themes captured the patients’ experiences: (1) feeling powerless, (2) being unable to recognise time, (3) feeling dead, (4) experiencing physical pain, and (5) having future concerns. Conclusion: The current study found that mechanically ventilated ICU patients suffer both physically and psychologically. Nurses should use specific strategies to relieve discomfort in addition to pain treatment. This is especially essential for non-verbal patients, whose actions may resemble those of their clinicians in pain.
Effects of Lymphaticovenous Anastomosis on Quality of Life, Body Image, and Spiritual Health in Lymphedema Patients: A Prospective Cohort Study
Authors: Peng Shu-Hui , Huang Ching-Ya , Shih Chun-Ming , Tsai Pei-Yu , Yang Johnson Chia-Shen , Hsieh Ching-Hua
Published: July 2024

Background: Lymphedema is a debilitating condition that significantly affects quality of life due to its chronic nature and visible symptoms. Lymphaticovenous anastomosis (LVA) has emerged as a promising surgical intervention, yet its effects on body image and spiritual health alongside physical symptoms have not been thoroughly examined. This study evaluates the efficacy of LVA in improving symptoms, quality of life (QOL), body image, and spiritual well-being in lymphedema patients. Methods: A prospective cohort study was conducted at Kaohsiung Chang Gung Memorial Hospital, Taiwan, involving 44 patients with lymphedema undergoing LVA surgery. Evaluations were made pre-surgery, one month post-surgery, and six months post-surgery using the 36-Item Short Form Health Survey (SF-36), Multidimensional Body–Self Relations Questionnaire-Appearance Scales (MBSRQ-AS), and a spiritual health scale. Statistical analysis was performed using one-way repeated measures ANOVA. Results: Significant improvements were observed in lymphedema symptoms and QOL measures at six months post-operation. SF-36 results showed enhanced scores in nearly all domains, particularly in physical functioning and role-physical. The appearance orientation scores from the MBSRQ-AS significantly increased, indicating improved perceptions in some dimensions of body image. Conclusions: LVA surgery significantly enhances physical and psychological outcomes in patients with lymphedema, with marked improvements in symptoms, QOL, and body image perceptions. The findings suggest that while LVA is effective in addressing the physical and psychological aspects of lymphedema, it does not impact spiritual dimensions. This underscores the need for holistic approaches in the management of lymphedema to address all facets of patient well-being.
New Evidence of Traditional Japanese Dyeing Techniques: A Spectroscopic Investigation
Authors: Geminiani Ludovico , Campione Francesco Paolo , Corti Cristina , Luraschi Moira , Recchia Sandro , Rampazzi Laura
Published: July 2024

The Japanese textile tradition is renowned for its intricate designs achieved through a variety of dyeing techniques, including kasuri, shibori, and paste-resist dyeing. These techniques are often combined within a single textile, resulting in exceptionally elaborate creations. Our paper delves into the technical aspects and complexities of these methods, highlighting the dynamic interplay between tradition and innovation in Japanese textile production. Our scientific endeavour focused on some textiles dating between the 19th and 20th centuries and belonging to the Montgomery Collection of Japanese folk art. Employing non-invasive techniques such as visible reflectance spectroscopy and ER-FTIR spectroscopy, we uncovered key insights into the materials and methods utilized in the creation of these textiles. Our analysis revealed a diverse array of pigments and dyes, including plant-derived, inorganic, and synthetic variants. These findings illuminate the cultural syncretism between traditional Japanese practices and the adoption of new materials from the West, underscoring the dynamic nature of textile production in Japan. Furthermore, ER-FTIR spectroscopy elucidated the predominant use of cotton as the primary fibre in the textiles, aligning with historical records of Japan’s role as a major producer of cotton yarn. Analysis of white areas within the textiles revealed evidence of resist-paste dyeing techniques, particularly tsutsugaki and katazome, through the absence of dye penetration and the characteristic appearance of white lines. Confirmation of indigo dyeing techniques (aizome) was achieved through ER-FTIR spectroscopy, providing reliable identification of indigo and Prussian blue in various shades of blue present in the textiles. Additionally, the detection of Western-derived dyeing method (utsushi-yūzen) and free-hand painting (kaki-e), offers insights into the diversity of dyeing practices employed by Japanese artisans. The presence of proteinaceous materials and synthetic dyes observed in some textiles has implications for conservation practices, suggesting the need for tailored approaches to ensure the preservation of these culturally significant artifacts. Overall, these scientific results shed new light on the materials, techniques, and cultural contexts underlying Japanese textile production, advancing our understanding of this rich artistic heritage and informing future research endeavours in textile science and conservation.
The Study of Pigments in Cultural Heritage: A Review Using Machine Learning
Authors: Harth Astrid
Published: July 2024

In this review, topic modeling—an unsupervised machine learning tool—is employed to analyze research on pigments in cultural heritage published from 1999–2023. The review answers the following question: What are topics and time trends in the past three decades in the analytical study of pigments within cultural heritage (CH) assets? In total, 932 articles are reviewed, ten topics are identified and time trends in the share of these topics are revealed. Each topic is discussed in-depth to elucidate the community, purpose and tools involved in the topic. The time trend analysis shows that dominant topics over time include T1 (the spectroscopic and microscopic study of the stratigraphy of painted CH assets) and T5 (X-ray based techniques for CH, conservation science and archaeometry). However, both topics have experienced a decrease in attention in favor of other topics that more than doubled their topic share, enabled by new technologies and methods for imaging spectroscopy and imaging processing. These topics include T6 (spectral imaging techniques for chemical mapping of painting surfaces) and T10 (the technical study of the pigments and painting methods of historical and contemporary artists). Implications for the field are discussed in conclusion.