bluuebunny/crossref_metadata_2025 huggingface dataset:
Differential Gene Expression Associated with Altered Isoflavone and Fatty Acid Contents in Soybean Mutant Diversity Pool
Authors: Kim Dong-Gun , Lyu Jae-Il , Lim You-Jin , Kim Jung-Min , Hung Nguyen-Ngoc , Eom Seok-Hyun , Kim Sang-Hoon , Kim Jin-Baek , Bae Chang-Hyu , Kwon Soon-Jae
Published: May 2021

Soybean seeds are consumed worldwide owing to their nutritional value and health benefits. In this study we investigated the metabolic properties of 208 soybean mutant diversity pool (MDP) lines by measuring the isoflavone and fatty acid contents of the seed. The total isoflavone content (TIC) ranged from 0.88 mg/g to 7.12 mg/g and averaged 3.08 mg/g. The proportion of oleic acid among total fatty acids (TFA) ranged from 0.38% to 24.66% and averaged 11.02%. Based on the TIC and TFA among the 208 MDP lines, we selected six lines with altered isoflavone content and six lines with altered oleic acid content compared with those of the corresponding wild-types for measuring gene expression. Each of twelve genes from the isoflavone and fatty acid biosynthesis pathways were analyzed at three different seed developmental stages. Isoflavone biosynthetic genes, including CHI1A, IFS1, and IFS2, showed differences in stages and expression patterns among individuals and wild-types, whereas MaT7 showed consistently higher expression levels in three mutants with increased isoflavone content at stage 1. Expression patterns of the 12 fatty acid biosynthetic genes were classifiable into two groups that reflected the developmental stages of the seeds. The results will be useful for functional analysis of the regulatory genes involved in the isoflavone and fatty acid biosynthetic pathways in soybean.
Comparative Analysis of Re-Annotated Genes Provides Insight into Evolutionary Divergence and Expressions of Aquaporin Family in Pepper
Authors: Lee Yeon Mi , Chae Geun Young , Kim Min Kyung , Kim Seungill
Published: May 2021

Aquaporins (AQPs) are known to have a vital role in water transport in all living organisms including agriculturally important crops, but a comprehensive genomic study of AQPs in pepper has not been implemented. Here, we updated previous gene annotations and generated a total of 259 AQP genes from five plants, including pepper. Phylogenetic and motif analyses revealed that a large proportion of pepper AQP genes belong to the specific subgroup of tonoplast intrinsic protein (TIP) subfamily, TIP4. Chromosomal localization and estimated duplication times illustrated that genes in TIP4 formed a tandem array on the short arm of chromosome 1, resulting from pepper-specific expansion after its divergence with Solanaceae species. Transcriptome analyses under various abiotic stress conditions revealed that transport-, photosystem-, and thylakoid-related genes were generally enriched in expression clusters containing AQP genes in pepper. These results provide valuable genomic resources and insight into the evolutionary mechanism that generate genomic diversity of the AQP gene family in pepper.
Factors Involved on Tiger-Stripe Foliar Symptom Expression of Esca of Grapevine
Authors: Calzarano Francesco , Pagnani Giancarlo , Pisante Michele , Bellocci Mirella , Cillo Giuseppe , Metruccio Elisa Giorgia , Di Marco Stefano
Published: May 2021

Esca of grapevine causes yield losses correlated with incidence and severity symptom expression. Factors associated with leaf symptom mechanisms are yet to be fully clarified. Therefore, in 2019 and 2020, macro and microelement analyses and leaf reflectance measurements were carried out on leaves at different growth stages in a vineyard located in Abruzzo, central Italy. Surveys were carried out on leaves of both never leaf-symptomatic vines and different categories of diseased vine shoots. Never leaf-symptomatic and diseased vines were also treated with a fertilizer mixture that proved to be able to limit the symptom expression. Results showed that untreated asymptomatic diseased vines had high calcium contents for most of the vegetative season. On the contrary, treated asymptomatic diseased vines showed higher contents of calcium, magnesium, and sodium, at berries pea-sized, before the onset of symptoms. These vines had better physiological efficiency showing higher water index (WI), normalized difference vegetation index (NDVI), and green normalized difference vegetation index (GNDVI) values, compared to untreated asymptomatic vines, at fruit set. Results confirmed the strong response of the plant to symptom expression development and the possibility of limiting this response with calcium and magnesium applications carried out before the symptom onset.
Dehydroabietic Acid Is a Novel Survivin Inhibitor for Gastric Cancer
Authors: Kim Won-Jin , Kim Woong , Bae Jang-Mi , Gim Jungsoo , Kim Seok-Jun
Published: May 2021

Gastric cancer is a malignant tumor with a high incidence and mortality rate worldwide. Nevertheless, anticancer drugs that can be used for gastric cancer treatment are limited. Therefore, it is important to develop targeted anticancer drugs for the treatment of gastric cancer. Dehydroabietic acid (DAA) is a diterpene found in tree pine. Previous studies have demonstrated that DAA inhibits gastric cancer cell proliferation by inducing apoptosis. However, we did not know how DAA inhibits the proliferation of gastric cancer cells through apoptosis. In this study, we attempted to identify the genes that induce cell cycle arrest and cell death, as well as those which are altered by DAA treatment. DAA-regulated genes were screened using RNA-Seq and differentially expressed genes (DEGs) analysis in AGS cells. RNA-Seq analysis revealed that the expression of survivin, an apoptosis inhibitor, was significantly reduced by DAA treatment. We also confirmed that DAA decreased survivin expression by RT-PCR and Western blotting analysis. In addition, the ability of DAA to inhibit survivin was compared to that of YM-155, a known survivin inhibitor. DAA was found to have a stronger inhibitory effect in comparison with YM-155. DAA also caused an increase in cleaved caspase-3, an apoptosis-activating protein. In conclusion, DAA is a potential anticancer agent for gastric cancer that inhibits survivin expression.
Rice Sesquiterpene Plays Important Roles in Antixenosis against Brown Planthopper in Rice
Authors: Kamolsukyeunyong Wintai , Sukhaket Wissarut , Pitija Kitsada , Thorngkham Pornwalai , Mahatheeranont Sugunya , Toojinda Theerayut , Vanavichit Apichart
Published: May 2021

The rice sesquiterpene synthase II gene (OsSTPS2, LOC_Os04g27430), which is involved in the antixenosis defense mechanism of rice against brown planthopper (BPH) infestation, was identified in the BPH-resistant rice variety Rathu Heenati (RH). In contrast, the gene was not functional in the BPH-susceptible rice variety KDML105 (KD). Single-nucleotide polymorphisms (SNPs) in the promoter region and in exon 5 of the gene and a seven amino acid deletion in the deduced protein sequence are suggested as factors that negatively regulate the function of the gene. Sequence analysis of the promoter region and expression analysis of the OsSTPS2 gene in several rice genotypes revealed the correlation of SNPs of the ATHB-1, SBE1, and P-factor with the expression of the gene. Genomic and complementary DNA (cDNA) sequence analysis at exon 5 of the gene showed that the 21 bp deletion naturally occurred in several rice genotypes. The antixenosis of the BPH feeding preference (AFP) of rice varieties differed in the seven amino acid deletion lesion of the gene, suggesting that the seven amino acid deletion negatively controls the antixenosis mechanism during BPH infestation. Analysis of the plant volatile compounds released after BPH infestation suggested that E-β-farnesene (EBF) is the major product of the OsSTPS2 gene.
Production and Characterization of Sumac PlantCrystals: Influence of High-Pressure Homogenization on Antioxidant Activity of Sumac (Rhus coriaria L.)
Authors: Abraham Abraham M. , Quintero Camilo , Carrillo-Hormaza Luis , Osorio Edison , Keck Cornelia M.
Published: May 2021

Oxidative stress diseases are usually treated or prevented by using antioxidants from natural or artificial sources. However, as a sustainable source of phytochemicals, plants got a renewed interest in obtaining their active agents using green extraction technologies, i.e., sustainable extraction techniques that reduce energy consumption, use renewable sources and result in less post-extraction wastes. The high-pressure homogenization (HPH) technique was introduced into the food industry since it was invented in 1900 to homogenize milk and later to produce fruit juices with a longer shelf-life without preservatives. Recently, HPH was introduced as an eco-friendly method to nanomill plants for improved extraction efficacy without using organic solvents. In this study, sumac was used as an antioxidants-rich spice model to investigate the effects of HPH on its antioxidant capacity (AOC). Sumac was rendered into PlantCrystals by using HPH. Particle size characterization proved the presence of submicron-sized particles (about 750 nm). Thus, HPH was able to produce sumac PlantCrystals and increased the AOC of bulk sumac by more than 650% according to the ORAC (oxygen radical absorbance capacity) assay. The polyphenol and flavonoid contents showed higher values after HPH. Interestingly, the DPPH (1,1-diphenyl-2-picrylhydrazyl) assay also showed a well improved AOC (similar to ascorbic acid) after HPH. In fact, in this study, the PlantCrystal-technology was demonstrated to cause an efficient cell rupture of the sumac plant cells. This caused an efficient release of antioxidants and resulted in sumac PlantCrystals with a 6.5-fold higher antioxidant capacity when compared to non-processed sumac bulk material.
Improved NSGA-III with Second-Order Difference Random Strategy for Dynamic Multi-Objective Optimization
Authors: Zhang Haijuan , Wang Gai-Ge , Dong Junyu , Gandomi Amir H.
Published: May 2021

Most real-world problems that have two or three objectives are dynamic, and the environment of the problems may change as time goes on. For the purpose of solving dynamic multi-objective problems better, two proposed strategies (second-order difference strategy and random strategy) were incorporated with NSGA-III, namely SDNSGA-III. When the environment changes in SDNSGA-III, the second-order difference strategy and random strategy are first used to improve the individuals in the next generation population, then NSGA-III is employed to optimize the individuals to obtain optimal solutions. Our experiments were conducted with two primary objectives. The first was to test the values of the metrics mean inverted generational distance (MIGD), mean generational distance (MGD), and mean hyper volume (MHV) on the test functions (Fun1 to Fun6) via the proposed algorithm and the four state-of-the-art algorithms. The second aim was to compare the metrics’ value of NSGA-III with single strategy and SDNSGA-III, proving the efficiency of the two strategies in SDNSGA-III. The comparative data obtained from the experiments demonstrate that SDNSGA-III has good convergence and diversity compared with four other evolutionary algorithms. What is more, the efficiency of second-order difference strategy and random strategy was also analyzed in this paper.
Designing of an Advanced Compression Bioreactor with an Implementation of a Low-Cost Controlling System Connected to a Mobile Application
Authors: Dursun Gözde , Umer Muhammad , Markert Bernd , Stoffel Marcus
Published: May 2021

(1) Background: Bioreactors mimic the natural environment of cells and tissues by providing a controlled micro-environment. However, their design is often expensive and complex. Herein, we have introduced the development of a low-cost compression bioreactor which enables the application of different mechanical stimulation regimes to in vitro tissue models and provides the information of applied stress and strain in real-time. (2) Methods: The compression bioreactor is designed using a mini-computer called Raspberry Pi, which is programmed to apply compressive deformation at various strains and frequencies, as well as to measure the force applied to the tissue constructs. Besides this, we have developed a mobile application connected to the bioreactor software to monitor, command, and control experiments via mobile devices. (3) Results: Cell viability results indicate that the newly designed compression bioreactor supports cell cultivation in a sterile environment without any contamination. The developed bioreactor software plots the experimental data of dynamic mechanical loading in a long-term manner, as well as stores them for further data processing. Following in vitro uniaxial compression conditioning of 3D in vitro cartilage models, chondrocyte cell migration was altered positively compared to static cultures. (4) Conclusion: The developed compression bioreactor can support the in vitro tissue model cultivation and monitor the experimental information with a low-cost controlling system and via mobile application. The highly customizable mold inside the cultivation chamber is a significant approach to solve the limited customization capability of the traditional bioreactors. Most importantly, the compression bioreactor prevents operator- and system-dependent variability between experiments by enabling a dynamic culture in a large volume for multiple numbers of in vitro tissue constructs.
A Framework in Calibration Process for Line Structured Light System Using Image Analysis
Authors: Luo Tianhong , Liu Suchwen , Wang Chenglin , Fu Qiang , Zheng Xunjia
Published: May 2021

Line structured light systems have been widely applied in the measurement of various fields. Calibration has been a hot research topic as a vitally important process of the line structured light system. The accurate calibration directly affects the measurement result of the line structured light system. However, the external environment factors, such as uneven illumination and uncertain light stripe width, can easily lead to an inaccurate extraction of light stripe center, which will affect the accuracy of the calibration. An image analysis-based framework in the calibration process was proposed for the line structure light system in this paper. A three-dimensional (3D) vision model of line structure light system was constructed. An image filtering model was established to equalize the uneven illumination of light stripe image. After segmenting the stripe image, an adaptive window was developed, and the width of the light stripe was estimated by sliding the window over the light stripe image. The light stripe center was calculated using the gray centroid method. The light plane was fitted based on the calibration points coordinates acquired by the camera system. In the measurement experiment of standard gauge block width, the maximum and minimum average deviations of 0.021 pixels and 0.008 pixels and the maximum and minimum absolute deviations of 0.023 pixels and 0.009 pixels could be obtained by using the proposed method, which implies the accuracy of the proposed method.
Association of the Yips and Musculoskeletal Problems in Highly Skilled Golfers: A Large Scale Epidemiological Study in Japan
Authors: Gon Yasufumi , Kabata Daijiro , Kawamura Sadahito , Mihara Masahito , Shintani Ayumi , Nakata Ken , Mochizuki Hideki
Published: May 2021

The yips are a set of conditions associated with intermittent motor disturbances that affect precision movement, especially in sports. Specifically, skilled golfers suffer from the yips, although its clinical characteristics and pathophysiology have not been well-studied. We surveyed skilled golfers to characterize their yips-related symptoms, to explore potential confounding factors associated with the yips. Golfers’ demographic information, golfing-career-related history, musculoskeletal status and manifestations of the yips are surveyed. Among the 1576 questionnaires distributed, 1457 (92%) responses were received, of which 39% of golfers had experienced the yips. The median age and golfing careers were 48 and 28 years, respectively. Golfers who had experienced the yips were older and had longer golfing careers and more frequent musculoskeletal problems than those without experience of the yips. The multivariate logistic regression analysis revealed that a longer golfing career and musculoskeletal problems were independent factors associated with yips experience. More severe musculoskeletal problems were associated with higher odds of experiencing the yips. A positive association between the yips and musculoskeletal problems was also observed. The yips have similar characteristics to task-specific movement disorders, with a detrimental effect caused by excessive repetition of a routine task. These findings support the notion that the yips are a type of task-specific dystonia.
Optical Forces on an Oscillating Dipole Near VO2 Phase Transition
Authors: Szilard Daniela , Abrantes Patrícia P. , Pinheiro Felipe A. , Rosa Felipe S. S. , Farina Carlos , Kort-Kamp Wilton J. M.
Published: May 2021

We investigate optical forces on oscillating dipoles close to a phase change vanadium dioxide (VO2) film, which exhibits a metal-insulator transition around 340 K and low thermal hysteresis. This configuration emulates the interaction between an illuminated nanosphere and an interface and we employ a classical description to capture its important aspects. We consider both electric and magnetic dipoles for two different configurations, namely with the dipole moments parallel and perpendicular to the VO2 film. By using Bruggeman theory to describe the effective optical response of the material, we show that the thermal hysteresis present in the VO2 transition clearly shows up in the behavior of optical forces. In the near-field regime, the force on both dipoles can change from attractive to repulsive just by heating (or cooling) the film for a selected frequency range. We also verified that the optical forces are comparable to the Casimir-Polder force in a similar system, revealing the possibility of modulating or even changing the sign of the resultant force on an illuminated nano-object due to the presence of a thermochromic material. We hope that this work contributes to set the grounds for alternative approaches to control light-matter interactions using phase-change materials.
Urban Policies and Large Projects in Central City Areas: The Example of Madrid (Spain)
Authors: García Dolores Brandis
Published: May 2021

Since the late 20th century major, European cities have exhibited large projects driven by neoliberal urban planning policies whose aim is to enhance their position on the global market. By locating these projects in central city areas, they also heighten and reinforce their privileged situation within the city as a whole, thus contributing to deepening the centre–periphery rift. The starting point for this study is the significance and scope of large projects in metropolitan cities’ urban planning agendas since the final decade of the 20th century. The aim of this article is to demonstrate the correlation between the various opposing conservative and progressive urban policies, and the projects put forward, for the city of Madrid. A study of documentary sources and the strategies deployed by public and private agents are interpreted in the light of a process during which the city has had a succession of alternating governments defending opposing urban development models. This analysis allows us to conclude that the predominant large-scale projects proposed under conservative policies have contributed to deepening the centre–periphery rift appreciated in the city.
FATORES SOCIOAMBIENTAIS NA EPIDEMIOLOGIA DA ESQUISTOSSOMOSE NO OESTE DA BAHIA, BRASIL
Authors: Rodrigues Dayane Otero , Pereira Larissa Hellen dos Santos
Published: May 2021

A Região Nordeste do Brasil é uma área de grande prevalência da esquistossomose, com destaque ao estado da Bahia, que apresenta grande parte do seu território como área endêmica da doença. A esquistossomose é um grave problema de saúde pública, já que a patogênese da doença pode levar o paciente ao óbito e dentre os fatores ambientais relacionados à sua transmissão destaca-se a falta de saneamento básico, uma vez que os ovos do parasita são eliminados nas fezes dos humanos podendo contaminar os mananciais aquáticos. O município de Barreiras, situado no Oeste da Bahia, é carente em condições básicas de saúde, principalmente nas áreas rurais, aumentando as chances de contaminação pelo helminto. Objetivos: Analisar a relação entre os fatores socioambientais e casos de esquistossomose em moradores do município de Barreiras, Oeste da Bahia. Metodologia: Foram coletados dados dos fatores de risco socioambientais e clínicos de 98 fichas de notificação obrigatória da Vigilância Epidemiológica de Barreiras de casos confirmados de esquistossomose dos anos de 2015 e 2018. Os dados foram analisados baseando-se nos testes qui-quadrado e exato de Fisher para verificar a associação entre as variáveis, sendo que o estudo se iniciou após aprovação pelo Comitê de Ética em Pesquisa da Universidade Federal do Oeste da Bahia. Resultados e Conclusão: A prevalência de esquistossomose em Barreiras é baixa em relação a outras regiões do estado. A maioria dos casos de infectados no município foi de moradores da zona rural, sendo que encontramos associação entre as variáveis forma clínica e idade dos infectados. Os fatores ambientais como a ausência de condições sanitárias adequadas com possível contaminação ambiental do município com os ovos do parasita e a presença de rios, córregos e represas na região com a presença do caramujo do gênero Biomphalaria favorecem a contaminação dos moradores principalmente da zona rural, mas também da urbana, em bairros sem infraestrutura e saneamento básico.
LAUDO TÉCNICO PERICIAL SOBRE INTERVENÇÃO AMBIENTAL IRREGULAR EM ÁREAS DE PRESERVAÇÃO PERMANENTE DE ZONA URBANA, ESTUDO DE UM CASO CONCRETO
Authors: Sickert de Almeida Rocha Hugo Frederico , Pires Sampaio Cristiane
Published: May 2021

O presente trabalho oferece o laudo técnico pericial realizado para apurar uma intervenção ambiental irregular em área sob regime especial de proteção, sendo ela definida pela legislação brasileira como área de preservação permanente (APP). Como forma de ilustrar as diversas faces e minúcias do trabalho técnico pericial, foi escolhido um cenário que apresenta como característica básica a supressão de vegetação em APP; Foram definidas as metodologias, os recursos tecnológicos, as análises realizadas e as possíveis ações para mitigação, compensação ou recuperação dos impactos causados aos recursos ambientais. Por tratar-se de caso real, os nomes, coordenadas geográficas e outros dados passíveis de identificar os envolvidos diretos serão alterados por pseudônimos e dados fictícios. Vale a ressalva que todas as informações contidas em um laudo técnico pericial são de domínio púbico e sujeitos a pesquisa por quem quer que seja; o cuidado na omissão dos dados visa, tão somente, a não exposição da figura de outrem.
ESTUDO GRANULOMÉTRICO EM SISTEMA DE FILTRAÇÃO DIRETA PARA TRATAMENTO DE ÁGUA DE ABASTECIMENTO COM USO DE COAGULANTES ORGÂNICOS E INORGÂNICOS
Authors: PEREIRA EDILAINE REGINA , Ioshimura Renato Akira , Peruço Theodoro Joseane Debora , Bicudo Bruna Ricci , Janz Fellipe Jhordã Ladeia
Published: May 2021

A presente pesquisa teve como objetivo comparar o desempenho do coagulante natural extraído da semente da Moringa oleifera com o desempenho do coagulante químico Sulfato de Alumínio no tratamento de água, e verificar a melhor granulometria da areia utilizada no processo de filtração direta. Para tal, foram realizados ensaios no equipamento Jar-Test seguido de filtração descendente direta. A concentração para ambos os coagulantes foi de 300 mg.L-1. Para a filtração foram utilizadas três granulometrias distintas: G1 (até 0,425 mm), G2 (0,425 a 0,850 mm) e G3 (0,850 a 1,70 mm). Os parâmetros analisados foram: pH, cor aparente, turbidez e condutividade elétrica. Os valores de pH, apesar da discreta variação, permaneceram dentro do padrão exigido pela Portaria n05 da Consolidação. A condutividade elétrica sofreu um aumento para ambos os coagulantes devido a presença de sais e proteínas (no caso da Moringa oleifera), e íons de alumínio (no caso do Sulfato de alumínio) na água tratada. Após o processo de filtração a eficiência de remoção de cor aparente dos coagulantes aumentou significativamente, tendo a granulometria G3 apresentado o melhor resultado para o coagulante orgânico (98%) e G2 apresentado melhor resultado para o coagulante inorgânico (96%). O tratamento utilizando o extrato da semente de Moringa oleifera associado à filtração com granulometria G3 (0,850 a 1,70 mm) foi a associação que obteve os resultados mais satisfatórios, comprovando a eficiência do coagulante orgânico associado ao processo de filtração no tratamento de água.
Mental reactions of doctors against the background of the SARS-CoV-2 pandemic (message 2)
Authors: Kinkulkina Marina Arkadievna , Gardanova Zhanna Robertovna , Novikov Vladimir Vladimirovich , Khritinin Dmitriy Fedorovich , Novikova Anna Mikhaylovna , Khritinin Aleksandr Dmitrievich
Published: May 2021

This article continues the review of the complex of mental reactions of doctors against the background of the SARS-CoV-2 pandemic (from anosognosia to severe anxiety and depressive disorders) described in message 1. Significant correlations were found between a number of indicators of experimental psychological research methods and the data from the questionnaire developed by us, which allows speaking about the influence of strategies for coping with stress behavior in doctors of various profiles on the quality of life and their mental responses.
HUMAN UNCONSCIOUS PROCESSES AS A FACTOR OF FORMATION OF THE OUTSIDE WORLD AND SOCIAL INTERACTIONS
Authors: Shylina N.
Published: May 2021

The article is devoted to the problem of the formation of personality in the modern information society and the influence of the unconscious person on the surrounding world. The author analyzes the psychoanalytic approach to the consideration of the personality by Z. Freud. The author also considers the conflict between the principle of pleasure and the principle of rationality and its influence on the interaction of personality and society. The author characterizes the psychoanalytic approach  of J.  Frankl.  The problem  of the mutual influence  of personality and society, namely the processes of interiorization and exteriorization, is revealed. The theory of E. Neumann about the influence of the unconscious on the functioning of consciousness is described in the article.E.  Edinger’s scientific work is also analyzed by the author. Parallels between the alchemical processes  of the unconscious person and their  reflection in the behavior and activities of the individual were made. The author analyzes also the modern view on the problem of person and reality in quantum mechanics. In this context, A. Puzikov’s approach is considered. The problem of objective and subjective realities has been raised. The concept of proto-reality is revealed in the article. The influence of the choice of personality from the endless options on the formation of actual reality is explained in the article.
TYPES OF INDIVIDUAL MEN EROTIC CODE
Authors: Sedykh K. , Zozul T.
Published: May 2021

The article is devoted to the current definition and justification of the men’s individual erotic code typology. Significant expansion and development of psychologists’ professional activity necessitate creating of generalized classification of individuals and married couples’ behavioral erotic types. The study of sexual- psychological characteristics of behavioral patterns of men in erotic relationships is very important in this regard.The new material on the topic under study is generalized. Erotic imagination functions and erotic images impact the process of forming a fixed erotic Image of a sexual partner in men are determined. The impact of early life experience (imprinting) influenced on the individual erotic code formation is described.Attention is concentrated on analysis of the phenomenon individual men erotic code. The types of men individual erotic code, based on the concept of archetypes (K. G. Jung, D. S. Bolen) study are defined. Types of individual erotic code were named after the ancient Greek gods: Zeus, Apollo, Hermes, Ares, Hephaestus, Dionysus, Hades. The attention is focused on the deep analysis of  individual women erotic code stages realization, such as, the genesis of erotic impulse, the tempting process, the sexual act behavior, the pregnancy, the caring of posterity.
THE SPECIFICITY OF VALUE ORIENTATIONS OF STUDENTS IN TECHNICAL PROFILE COLLEGES
Authors: Verbova Yu.
Published: May 2021

The article is aimed to reveal the specificity of colleges technical profile student’s value orientations. Theoretical analysis of modern scientific researches of value orientation’s role in the college student’s professional becoming are presented. The results of empirical research of value-motivational types, terminal and instrumental values of college students are analyzed. the prevailing value orientations of the technical profile college students are the focus on improving material well-being, achievement of social status and recognition, achievement in various spheres of life and manifestation of autonomy are described. The role of instrumental values of freedom, sense of life, self-esteem, creativity, self-discipline and authority in student’s learning activity are represented.
DEVELOPMENT AND APPLICATION OF SYSTEMIC FAMILY THERAPY - AN ASSESSMENT OF THE SITUATION IN THE EXPIRING SECOND DECADE OF THE 21ST CENTURY AND THE CHALLENGE OF A GENDER-SENSITIVE NEW ORIENTATION
Authors: Velasquez-Montiel S.
Published: May 2021

It is always helpful to take a closer look at the development in order to understand the situation. Therefore, we would like to give a short outline of the development of the systemic therapy, which resulted from the general system theory, at this point, whereby no claim to completeness exists. The general systems theory is based on different scientific methods that initially emerged independently.The considerations of the biologist Ludwig von Bertalanffy can be mentioned as general basics, as well as the concept of cybernetics developed by Norbert Wiener and W. Ross Ashby. These approaches were further developed by the action-theoretical system theory according to Parsons and the introduction of the term «organization» by Luhmann. The aim of general systems theory is to enable more accurate predictions of system behaviour.
DYNAMICS OF ADOLESCENT’S FROM INFORMAL UNIONS MEANING SPHERE INDICATORS IN THE TRAINING PROCESS
Authors: Lavrinenko V.
Published: May 2021

The article analyzes the features of value-meaning sphere development program participants meaning sphere dynamics indicators. The role of subcultures in modern society, directions of scientific research in the field of adolescents meaning sphere formation in informal associations current scientific research are presented.

The adolescent’s from informal unions value-meaning consciousness in the context of their communicative experience in subcultures integration development program purpose and content are described. The meaning orientations, meaning sphere structural and content characteristics and the severity of the meaning crisis of adolescents who took part in the approbation of the program dynamics indicators are analyzed.

The program approbation results proved its effectiveness by increasing the meaningfulness of adolescent’s from informal unions life, their reflexivity, quantitative characteristics of the meanings system while reducing the meaning of life crisis and negativism manifestations.
GENDER DIFFERENCES IN READINESS FOR MARRIAGE OF HIGH SCHOOL PUPILS
Authors: Тykhonenko N.
Published: May 2021

The article is devoted to the analysis of gender differences in readiness for marriage of high school pupils. It systematizes the factors of psychological readiness of young men and women for family life in today’s conditions. Adolescence, as a time of individual’s vital self-determination, is characterized by the experience of various social roles and activities. Psychological readiness for family life includes a stable positive motivation to start a family, the development of personal qualities of the family man, the ability to empathically understand the partner, constructive and self-affirming behavior in marriage.

Theoretical analysis of the peculiarities of personality formation in adolescence, the specifics of readiness for marriage and family-role expectations of senior school age pupils; methodical bases and methods of research are described. The results of an empirical study of gender differences in marriage readiness of high school pupils, their focus on understanding, emotional attraction and authority in marriage are analyzed.

It was found that girls are characterized by a strong motivational willingness to start a family, more focused on understanding with a partner and emotional involvement in the relationship. They are clearly aware of the specifics of family responsibilities, their own role in family life, the specifics of the organization of married life. Instead, for boys, the process of exercising authority and taking a dominant position in communication is more important. Girls consider the most important to be the achievement of a common point of view, acceptance from a partner, demonstration to him of acceptance of his position. In the success of family interaction, they pay special attention to emotional interaction and intimacy, manifestations of love and support.

The boys, on the other hand, strive to realize their authority and dominance in family relations, expect the woman to submit to their position and views, without giving a special role to issues of understanding and emotional inclusion. They have no intrinsic motivational need to start a family. Young people think little about the relationship between family roles, the organization of family life and building a system of support for family life.
SPIRITUAL AND MORAL ASPECTS OF PROFESSIONAL SOCIALIZATION OF PSYCHOLOGY STUDENTS
Authors: Koniaieva L.
Published: May 2021

The article highlights the actual problem of spiritual and moral aspects of professional socialization of modern student youth, and in particular psychology students. The concepts of professional socialization, morality, spirituality are analyzed. The materialistic and religious points of view in understanding spirituality are considered.

It was found that student youth is in the most intensive phase of socialization, which is associated with studying at a higher educational institution, and the important factors of professional socialization of students are the motivation and moral orientation of the individual, professional worldview, the values of professional activities of specialists and the system of value orientations. A theoretical analysis of the literature has shown that value orientations are a spiritual phenomenon, the essential basis of a person, a mechanism for self-organization of her spiritual world, and a person's moral self-determination is closely related to the level of his spiritual development. The connection of universal human moral values with personal and professional is the driving force behind the development of a specialist, and the conscious development of value orientations in students and the purposeful formation of spiritual and moral values in them are necessary for their successful professional socialization.

The profession of a psychologist requires increased attention to the moral side of the functions performed, since his professional activity is directly related to interaction with people, influence on their inner world. Therefore, the ethics of his work is based on universal human moral values. In the professional activity of a psychologist, the main ones are the ideals of the free and all-round development of the personality and its respect, the rapprochement of people and a pronounced orientation towards the value of another person. Therefore, spiritual and moral development is a priority in the process of professional socialization of psychology students, during which special attention should be paid to the formation of the moral self-concept of personality, virtues, empathy, self-esteem and the assimilation of moral values of the professional activity of psychologists, taking into account their ethical code.
Популізм і вибори в контексті глобалізаційних змін
Authors: Кіянка І. , Левицька Н.
Published: May 2021

Акцентовано увагу на особливостях популізму та виборах у контексті глобалізаційних процесів. Звернено увагу на феномен популізму та популістських ідеологій у  соціально-політичному житті багатьох країн світу. Зазначено, що на відміну від традиційних ідеологічних систем, популізм залежить від особливостей різних національних політичних культур, конкретної сукупності обставин соціально-економічного та політичного життя певної країни. Проведено аналіз виборів та виборчих кампаній, які використовують популістські гасла щодо отримання влади та вплив глобалізаційних процесів на сучасне політичне життя.
Нова стратегія національної безпеки України: реальна оцінка викликам і загрозам
Authors: Хаварівська Г.
Published: May 2021

Розкрито передумови прийняття Стратегії національної безпеки України. Проведено порівняльний аналіз із аналогічними попередніми документами. Проаналізовано основні виклики та загрози національній безпеці в умовах сьогодення, серед яких зміни клімату, російська агресія проти України, загострення геополітичного суперництва, поширення коронавірусної хвороби та інші безпекові загрози. Розглянуто основні пріоритетні напрямки розвитку системи безпеки та оборони згідно із Стратегією.
Медичний сектор: орієнтованість на пацієнта як отримувача медичних послуг
Authors: Барзилович А.
Published: May 2021

Зазначено, що реалії сьогодення вказують на те, що підвищення показників здоров’я населення можливо досягнути, якщо приділяти належну увагу пацієнту. Зауважено, що лікар і пацієнт є основними суб’єктами надання та отримання медичних послуг. Доведено, що основною сутністю їх взаємовідносин стає надання та отримання медичної допомоги, а також задоволення цільових потреб як надавача, так і споживача медичних послуг. Вказано, що орієнтованість медичного сектора на пацієнта як основного отримувача медичних послуг – це важливий показник оцінки якості роботи медичних закладів, а задоволеність пацієнта роботою медичного сектора є показником рівня її якості. Проведено аналіз задоволеності пацієнтами медичними послугами. Проаналізовано основні засади і принципи системи надання медичних послуг пацієнту.
Готовність закладів охорони здоров’я України до автономізації
Authors: Іщенко Г. , Юристовська Н.
Published: May 2021

Розглянуто рівень готовності та спроможності організаторів охорони здоров’я та працівників закладів охорони здоров’я різних рівнів надання медичної допомоги до проведення автономізації закладів охорони здоров’я. Доведено низький рівень готовності та спроможності організаторів охорони здоров’я та працівників закладів охорони здоров’я різних рівнів надання медичної допомоги до проведення автономізації закладів охорони здоров’я. Визначено, що цей рівень готовності організаторів охорони здоров’я та працівників фінансово-економічних служб не дозволить ефективно провести автономізацію закладів охорони здоров’я.
Paulo Freire y su legado político pedagógico en la sistematización de experiencias emancipatorias
Authors: Ruiz Muñoz María Mercedes
Published: May 2021

En este trabajo se presenta la recuperación del pensamiento freireano a la luz de la reconstrucción de experiencias a partir de la voz de los sujetos. La marca de Paulo Freire en el campo de la investigación educativa juega de manera significativa en la producción del conocimiento y en los saberes que emergen de los procesos de constitución de sujetos. La mirada analítica de la imbricación de lo político y lo pedagógico opera como una lógica de intelección para analizar los procesos educativos que se dan más allá de la escuela y al interior de la misma. De acuerdo con Paulo Freire, no se puede aludir a lo educativo sin lo político y a lo político sin lo educativo. En este sentido, la sistematización de experiencias opera bajo estos registros y otorga un sentido particular a la narrativa de los sujetos.
Paulo Freire y los aportes anticoloniales de Frantz Fanon, Albert Memmi y Amílcar Cabral
Authors: Fernández Moujan Inés
Published: May 2021

En este artículo analizo la dimensión de “lo político” en la pedagogía freireana. Para ello focalizo en los aportes teóricos de tres intelectuales anticoloniales: Frantz Fanon, Albert Memmi y Amílcar Cabral. Las narrativas políticas de estos tres pensadores influyeron de manera preponderante en la escritura de Paulo Freire. Sitúo mi análisis en el período del exilio de Paulo Freire (1964-1982), momento en el cual tiene una producción intelectual prolífica, al mismo tiempo que participa activamente en los debates y revoluciones de los pueblos latinoamericanos, caribeños y africanos. Me interesa destacar en este escrito las influencias políticas de los pensamientos de estos intelectuales en la teoría freireana. Respecto a Fanon, me centro en el aspecto político epistémico y racial, es decir las categorías que le provee a Freire referidas a la “conciencia dual”, “lo racial” y la “descolonización”; en relación a Memmi, presento el problema de la “deshumanización” del colonizadx; en cuanto a Amílcar Cabral, refiero a su posición anticolonial y a su idea de “descolonización de las mentes” y “resistencia cultural”. Estas categorías le permitieron a Freire reformular sus presupuestos iniciales sobre la liberación y proponer una pedagogía “con” los oprimidos.
Isolation and Toxin Typing of Clostridium Perfringens From Sheep, Goats, and Cattle in Fars Province, Iran
Authors: Hayati Masoumeh , Shamseddini Mehrdad , Tahamtan Yahya , Sadeghzadeh Safar , Manavian Mohsen , Nikoo Davood
Published: May 2021

Background: Clostridium perfringens is an important anaerobic bacterium found in the intestine of some livestock. It is concerned with the etiology of some diseases including enterotoxaemia. Various diseases are caused by different types of C. perfringens. Nonetheless, there is no published research on molecular typing and distribution of this pathogenic microorganism in Fars province. Objectives: Accordingly, our study focused on the isolation and toxin typing of C. perfringens from sheep, cattle, and goats in different parts of Fars province by the culture and the polymerase chain reaction (PCR) method. Materials and Methods: Approximately 459 fecal samples were collected and cultured on defined media for the isolation of C. perfringens. The confirmed isolates were genotyped by the PCR method using specific primers. Results: C. perfringens was isolated from 30.93% of the total samples. The results of toxin typing showed a total of 76 (54%), 13 (9%), 30 (21%), and 23 (16%) isolates as types A, B, C, and D, respectively. Conclusion: Our results indicated that C. perfringens type A was the most common type in sheep, cattle, and goats while the lowest number of isolates belonged to type B. Finally, the isolation of C. perfringens and toxin typing increase our knowledge of the epidemiology of these diseases and can help in the vaccine industry and better controlling related diseases.
Inhibitory Effect of Different Types of Fermented Milk on Candida albicans
Authors: Azizkhania Maryam , Sarisb Per Erik Joakim , Baniasadic Mehdi
Published: May 2021

Background: Candida albicans (C. albicans) is known as an opportunistic fungal pathogen, and although it is a normal flora of the gastrointestinal tract, it has the ability to colonize every human tissue, causing serious and invasive infections. Objective: This study focused on the antifungal activity of the produced yogurts and kefirs from cow, camel, sheep, and goat milk against C. albicans during the storage period at 4 º C. Materials and Methods: The pH, titratable acidity, the content of some organic acids, and anti-Candida activity of yogurt and kefir samples were evaluated based on the aim of the study. Results: The titratable acidity of the samples significantly increased after the fermentation, along with pH reductions. The concentration of lactic and pyruvic acids increased during the fermentation while citric, uric, and hippuric acid content demonstrated a decrease. The results revealed that kefir samples had a stronger anti-Candida effect compared to yogurt samples. On the first day of the storage period, the growth inhibitory effect of sheep milk kefir was 90.20%, followed by camel kefir (78.37%), goat kefir (74.52%), cow kefir (73.23%), sheep yogurt (48.56%), camel yogurt (37.51%), cow yogurt (34.42%), and goat yogurt (30.32%). Eventually, the inhibition rate of sheep milk kefir reached 96.50% after 20 days of storage. Conclusion: It seems that kefir may be used as a nutraceutical and functional food against C.albicans infections.
Acute Pancreatitis Caused by COVID-19 in a Child: A Case Report
Authors: Gholami Mehri , Arjmand Reza
Published: May 2021

Coronavirus disease 2019 (COVID-19) occurs in children as well as adults and it is mainly associated with symptoms of respiratory and gastrointestinal infections. The patient was a 13-year-old child who had no symptoms of a respiratory infection and complained of abdominal pain and vomiting. A COVID-19 polymerase chain reaction (PCR) test was requested, which was positive. Based on laboratory test results indicating high serum amylase and lipase levels and imaging findings, acute pancreatitis was diagnosed, and after supportive treatment, the patient was discharged in good general condition. During the SARS-CoV-2 pandemic, children who refer to medical centers with gastrointestinal symptoms and pancreatitis should be checked for COVID-19.
Madelung Deformity: Surgical Correction with Radial Dome Osteotomy
Authors: M. Corain , M. Giardini , A. Bissoli , G. Palazzolo , G. Bevilacqua , Zanotti Filippo
Published: May 2021

Madelung deformity is a rare wrist malformation caused by a growth disturbance of the palmar and ulnar part of the distal radial physis.
The aim of this study is to evaluate the outcome of radial dome osteotomy in patients affected by Madelung deformity. The endpoint of this operation is to improve the orientation of the articular surface of the radius, so as to support to the carpal bones.
Between 2017 and 2019, in our clinic, 4patients were treated using this technique. Post-operative pain was evaluated using the NRS. Functional outcomes were assessed through evaluation of ROM, grip strength via Jamar dynamometer and using DASH questionnaire. The aesthetic defects were estimated using a section of the Michigan Hand Outcome Questionnaire. Correction of deformities was evaluated on post-operative RX using McCarrol Criteria. Were also analyzed the accuracy and tolerance of the plates used.