bluuebunny/crossref_metadata_2025 huggingface dataset:
Information technologies in the education of contemporary China: reality and opportunities
Authors: Wei Sun
Published: July 2023

With the rapid development of modern information technologies, their integration into all areas of education is accelerating, which contributes to the penetration of innovations into the education space. The author emphasizes that the design of many educational technologies was focused on the goals of education and included a sufficient number of educational concepts and elements. However, if teachers blindly adhere to the traditional concept of “technology is only a tool”, then this creates a sense of superiority of their own status and a narrow understanding of the value of technology.

The author relies in his research on the latest achievements in the field of not only high technologies that are used in education, but also on psychological and social research on the impact of the latter both on education and on a person. The author proposes to perceive technologies in the context of a new culture, and shows possible ways of their more adequate use. Working with artificial technological objects is not only the acceptance of an artificial object, but also the adoption of a technical culture, which indicates a new cultural relationship between people and technology, and vice versa. On the basis of analyzing the phenomenon and essence of contemporary information technology, the author of this article tries to find out the problems existing in the application of contemporary information technology in education through a questionnaire survey, and reflects on the influence of technology on teachers and students in the education system.

The answers of the survey participants made it possible to present a picture of the use of information technologies in education as a holistic and complex process. The analysis of the results obtained, as well as everyday practical training in the skills of using high technologies, enabled the author to establish that the influence of information technologies on education is complex, this is a new stage in the development of education as a whole, which allows us to characterize the process of their use as a holistic system. The influence of technology has completely changed all structures and all participants in education. The results of the survey also made it possible to identify a number of problems that indicate shortcomings in the modern space of education, the didactic nature of learning in the sense of conveying and receiving information in new conditions (we are talking not only about digitalization as a process, but also about changes aimed at transforming teaching methodology).
Experts, expertise and philosophy
Authors: Zborovska Xenija
Published: July 2023

This article outlines the relevance and significance of the philosophical analysis of the essence of expertise by drawing upon existing Western contributions within the “philosophy of expertise” and offering author’s vision of this issue. Due to the postulation of the importance of expertise as a social phenomenon, the emphasis has been shifted from the expert himself to those actors who use his expertise.

The main part of the article is devoted to author’s concept of the three dimensions of expertise: ontic, deontic, and epistemological. The ontic dimension of expertise encompasses the phenomena of the objectual-sensory world that reflect the basis of an expert’s competence and involvement in a community of professionals. However, since expertise is a social activity rather than solely individual, alongside the ontic dimension of contextually verified competencies, there is a mandatory presence of a special responsibility on the expert’s behalf, leading to the discussion of the deontic dimension. As the epistemological dimension is one of the most debated in the context of the philosophy of expertise, its elucidation proves to be the most intricate and intriguing within this work. It raises questions regarding the dual nature of knowledge, the epistemic conditions of expertise quality, such as understanding (relevant terms, arguments, etc.), and the presence of propositional justification. This section concludes with an argument for the necessity of simultaneously considering all three dimensions when analyzing real-world expertise. Furthermore, by appealing to real social practices, the second part of the article attempts to demonstrate that the foundation of expertise analysis is deeply rooted in European civilization, starting from Socratic inquiries. Socrates began scrutinizing the epistemic value of ancient experts in light of the socio-political crisis of that time, including crises in the humanitarian sphere. Such a preliminary review of this issue should provoke a discussion, the expression of certain assessments and remarks, which will turn into a full-fledged professional discussion.
PLANING RENAL PUNCTURE IN MINI-PERCUTANEOUS NEPHROLITHOTOMY:A RADIOLOGICAL ANATOMYBASED INTERVENTION
Authors: Muhammad Izhar  , Riaz Ahmad Khan  , Anwar Hayat  , Qaiser Iqbal  , Shehzad ur Rehman  , Asif khan
Published: July 2023

Objectives: To determine the outcome of mini-PCNL in terms of stone clearance considering renal puncture through diff erent calyces under fl uoroscopy.Materials and Methods: This study was conducted in the Department of Urology Institute of Kidney Diseases , Peshawar from 1st Jan 2022 to 31st May 2022. Patients fulfi lling the study criteria having renal stone≥2cm were recruited for the study. All the patients having abnormal blood caogulopathy and abnormal anatomy were excluded from the study. The cystoscopy was performed fi rst by keeping the patient in the lithotomy position and the ureteric catheter was passed. The anatomy of kidney is fully visualized targeting the calyx with gradual descent technique under fl uoroscopic guidance. Renal access to pelvicalyceal (PVC) system achieved percutaneously under fl uoroscopic guidance by renal puncture through diff erent calyces after which which guide wire was passed. The percutaneous tract was made and dilated up to 17Fr by using single-step metalic dilator and a 12-Fr-sized nephroscope was used. The stones were broken into pieces using pneumatic lithoclast.Results: Mean stone size was 15.35+3.073. Mean hospital stay was 2.62+0.487. Ninety six(60%) were male patients while 64 (40%) were female patients. 71.9%(115) patients achieved stone clearance by intervention through middle calyx while 21.85% (35) and 7%(10) patients achieved full stone clearance through upper and lower calyx approach respectively.Conclusion: The approach to the pelvicalyceal system through proper planning of renal puncture under fl uoroscopic guidance turns signifi cantly good in case of middle calyceal approach in terms of stone clearance.
INTRA-ARTICULAR INJECTION OF CORTICOSTEROIDS MIXED WITH LOCAL ANAESTHETIC FOR INTERNAL DERANGEMENT OF TEMPOROMANDIBULAR JOINT (DISC DISPLACEMENT WITHOUT REDUCTION)
Authors: Akbar Zainab , Ahmad Waseem , Farhan Farha , Shah Zainab , Ullah Umer , Gul Khaula
Published: July 2023

Objectives: To determine the mean change in pain and mouth opening after intra-articular corticosteroid injection mixed with local anesthetic in patients of temporomandibular joint internalderangement (disc displacement without reduction).Materials and Methods: A Quasi-experimental study was conducted at the Oral and MaxillofacialSurgery Department, Armed Forces Institute of Dentistry (AFID), Rawalpindi; from February2016 to December 2019. Patients of either gender, aged between 16-70 years, presenting withdisc displacement without reduction were included in the study. Intra-articular injection of corticosteroids mixed with local anesthetic was administered into the aff ected joint. Pin using a Visualanalog scale (VAS) and maximum mouth opening (MMO)using a vernier caliper were measuredin every patient before and one week after the intra-articular injection. Data were entered in thestatistical package for social sciences (SPSS) version 22 for analysis.Results: A total of 107 patients were included in the study with a mean age of 30.5 ±6.92 years(range 17 to 42 years). The mean pre-injection VAS score for pain was 6.29±1.06 which decreasedsignifi cantly to 3.46±1.07at at one week following injection (p=<0.001) with a mean decreaseof 2.83±1.03. This improvement in VAS score with injection was signifi cant across all age, gender, educational and occupational groups. The mean pre-injection MMO was 28.76±4.20 whichincreased signifi cantly to 38.89±3.88at at one week following injection (p=<0.001) with a meanincrease of 10.0±3.33.
CONGENITAL UTERINE ANOMALIES OBSERVED IN PREGNANT FEMALES PRESENTING AT PUBLIC SECTOR GOVERNMENT MATERNITY HOSPITAL OF PESHAWAR, KHYBER PAKHTUNKHWA
Authors: Iftikhar Shazia , Naz Falak , Rehman Zainab , Deeba Farah , Bibi Saeeda , Haris Muhammad , Haris Sobia
Published: July 2023

Objectives: The objective of current study is to fi nd out the prevalence and types of the uterineanomalies in the pregnant patients in our population of Khyber Pakhtunkhwa.Materials and Methods: This was a descriptive study carried out in a public sector maternityhospital of Peshawar. A total of 834 pregnant ladies fulfi lling the inclusion criteria were admittedinthe hospital during the aforementioned time period for delivery. All patients were examinedpervaginum and also ultrasound examinations were performed. The normal anteverted positionoranomalous retroverted positions of uterus along with other anomalies like septate uterus andindented uterine fundus were recorded by ultrasonography.Results: Out of 834 cases 108 cases were delivered by cesarean section while 726 cases weredelivered by normal vaginal delivery. The number of uterine anomalies were recorded. It was foundthat out of 834 patients, there was one patient (0.11%) having septate uterus. There wasanothersingle case of indented uterine fundus (0.11%) which was discovered accidentally duringcesareansection. The indication for surgery was transverse lie of the fetus. Two out of 834 caseswere foundto be having retroverted uteri. They were found to be having retroverted uteri (0.23%)during theirroutine ultrasonographic examination.
Revisão sistemática integrativa da literatura sobre prática no modelo psicossocial no campo infantojuvenil e suas respectivas famílias no Brasil
Authors: Ferrari Andressa de França Alves , Menezes Christine Paula , Rego Vanessa Ribeiro
Published: July 2023

Objetivo: Aprofundamento dos estudos para a elucidação do cenário da Atenção Psicossocial infantojuvenil e suas famílias no Brasil. Metodologia: Foi realizado uma revisão integrativa sistemática da literatura indexada em uma revista com classificação igual ou superior a B2, segundo avaliação do WebQualis (2014), entre 2018 a 2022 nas bases de dados da Biblioteca Virtual em Saúde (BIREME) e SCIELO (Scientific Electronic Library Online). Os artigos publicados deveriam estar em língua portuguesa, na íntegra e disponibilizados online, para área da saúde e descrever práticas em atenção psicossocial infantojuvenil e suas famílias.  Resultados e Discussão: Verificou-se que todos os artigos trazem a necessidade de maior intersetorialidade nas práticas de atenção psicossocial, principalmente quando o público alvo são crianças, adolescentes e seus responsáveis. Bem como o modelo de atendimento prestado a essa população. Conclusão: Os resultados apontaram para uma preocupação maior no campo intersetorial e multiprofissional dado a complexidade do tema.  Frente ao exposto, é de importante relevância que o cuidado voltado para os familiares seja por meio do diálogo respeitando suas dimensões psicológica, social e espiritual, auxiliando para um cuidado humanizado.
Oleg Lazarenko’s Mosaic Color Painting: Features of Plastic Language
Authors:   Kharkiv State Academy of Design and Arts, Naydenko Viktoriia
Published: July 2023

The article examines the work of the Kharkiv art school and a member of the art association Burime, artist and designer Oleg Lazarenko. The article highlights the problem of color, which was actively raised by the Impressionists, and was subsequently picked up and comprehended by avant-garde movements. The genesis of color painting as an artistic technique in the art of the twentieth century is traced. Attention is focused on the avant-garde traditions, in particular, collage, suprematism and op-art, which greatly influenced the formation of the artist’s pictorial manner — mosaic color painting. The circle of postmodern innovations is revealed, which can be traced in the author’s manner of painting. It was revealed that in his creative activity the artist uses several pictorial techniques, which can be classified as follows: “plein air painting”, “mosaic color painting”, “oil color painting”. In addition, the art history analysis of the works showed his potential as a color painter and demonstrated the artist’s ability to go beyond the framework of a two-dimensional canvas with the help of optical illusions, color transitions, and influence the psychological state of the viewer. The origins of the design component in the master’s painting, which originate from the time of study at the “Khudprom” (Kharkiv State Academy of Design and Fine Arts) and have a significant impact on the author’s writing technique. The connection of the artist’s pictorial language with the ancient artistic culture is traced, which is expressed through Lazarenko’s appeal to the Trypillian ornamentation and Ukrainian folk traditions. The author reveals the relationship between religious art and icon-painting reminiscences of the master, which are transmitted through mosaic and oil color painting and illuminated in sacramental images on canvas. An art history analysis of O. Lazarenko’s selected works, performed in the technique of mosaic and oil color painting, is carried out, and the peculiarities of their structural-compositional and figurative-meaningful solutions are revealed.
Abbreviating the Early Start Denver Model for community-based family-centered care
Authors: Vismara Laurie A. , Nyugen Lucy , McCormick Carolyn E. B.
Published: July 2023

Introduction

Parent-mediated approaches for young children with or with a higher likelihood of autism have gained traction, with mounting evidence of efficacy, but a research-to-gap practice exists, and community effectiveness remains to be firmly established.

Methods

Using a community-participatory framework, a total of 10 parent-child dyads received a five-day workshop and six follow-up sessions of ESDM parent coaching. Intervention was implemented across two phases with in-person and telehealth delivery.

Results

From pre to post intervention across both phases, parents improved in their fidelity of intervention implementation and children maid gains on proximal measures of social communication.

Discussion

Community delivery of an evidence-based parent-mediated interventions for toddlers on the autism spectrum is feasible and promising. Giving resource efficiencies associated with parent-mediated approaches, particularly when delivered through government-funded programs, findings bolster current efforts to promote earlier and more widespread community access to necessary interventions. Facilitators and barriers to supporting parent learning and behavior change via interactive strategies are discussed.
Functional characteristics and subjective disease perception in patients with COVID-19 two months after hospital discharge
Authors: Teraž Kaja , Šimunič Boštjan , Peskar Manca , Marusic Uros , Pišot Saša , Šlosar Luka , Gasparini Malden , Pišot Rado
Published: July 2023

Introduction

Although early inpatient and post-hospital rehabilitation is recognized as necessary, not all COVID-19 patients have access to rehabilitation. There are no published reports in the literature that investigate the outcomes of patients who do not receive rehabilitation after COVID-19. Our aim was to evaluate possible improvements in determinate functional and psychological parameters in COVID-19 patients two months after their hospital discharge.

Methods

On both time points various motor, cognitive, and clinical measurements such as body composition, tensiomyography, blood pressure, spirometry, grip strength test, Timed Up and Go test, gait speed, 30-second chair-stand test, and Montreal Cognitive Assessment, were performed. Additionally, questionnaires such as the SARC-CalF test, Edmonton frail scale, International Physical Activity questionnaire andThe Mediterranean Lifestyle index were conducted to assess lifestyle characteristics.

Results

A total of 39 patients (87.2% male; mean age of 59.1 ± 10.3 years), who were hospitalized due to COVID-19 at the Izola General Hospital (IGH), Slovenia between December 2020 and April 2021, were included. Patients were assessed at two time points (T1 and T2): T1 was taken after receiving a negative COVID-19 test and T2 was taken two months after T1. After two months of self-rehabilitation, we have detected a BMI increase (p < .001), fat free mass increase (p < .001), better Edmonton frail scale (p < .001), SARC-CalF score (p = .014) and MoCA score (p = .014). There were no detected changes in lifestyle habits nor in physical performance tests.

Discussion

It is already known that COVID-19 has long-term negative consequences regardless of the stage of the disease. Our findings support the notion that patients cannot fully regain all their functions within a two-month period without receiving structured or supervised rehabilitation. Therefore, it is crucial to offer patients comprehensive and structured rehabilitation that incorporates clinical, cognitive, and motor exercises.
Women representation in soil science: gender indicators in the University Program of Interdisciplinary Soil Studies
Authors: Hernández Jhoana , Rodríguez-Bustos Laura , Barreras Aylin , Caballero Lizeth , Lara Ilce , Guevara Mario , Lopera Ana , Vázquez-Lule Alma , Torres-Gómez Mariano , Prado Blanca
Published: July 2023

Introduction

In the world, 33% of soils are degraded, and 2.9 million people are affected by land degradation, with problems associated with food security, conflicts over natural resources, and migration with different impacts on men or women. To support sustainable soil management, it is necessary to include women’s contributions to soil Sciences; their achievements and academic performance still need to be represented. Women in Science represent 30% worldwide. In Mexico, only 24% of top academic positions are women. For commitment to soil Sciences for Sustainable Development Goals (SDGs), UNAM created the University Program for Interdisciplinary Soil Studies (PUEIS).

Methods

This research evaluates women’s representation through gender indicators in the PUEIS and SNI datasets and discusses their implications for the gender gap in the soil Science community from Mexico. The data was collected with an online semi-structured survey and the gender indicators selected were related to participation, gender gap, sexism, equal opportunities, exclusion, and academic performance.

Results

The results show that in the PUEIS, 54% of members identify themselves as women and 46% as men. The gender gap shows equality in the total number of members. However, low-rank jobs, such as lecturers and lab technicians are women dominated, and the top-ranked positions as a full professor, associate professor, and research scientist are equal. One result to consider for the PUEIS members is that the younger generation, as is the older generation, is dominated by men. This could indicate a setback in intermediate generations’ progress toward achieving gender equality. In the case of SNI members, there is a gender gap problem; of members with a Ph.D. degree, only 38% are women, and the elite group of scientists with a Ph.D. at the top position is represented only by 24% of females.

Discussion

This work constitutes the first gender exercise for analyzing women’s participation in the soil Sciences in Mexico. From our perspective, it is not about competition in scientific careers between women and men; however, it is essential to recognize that gender inequalities are related to income, professional development, and science funding inequalities, and these disparities impact women more than men.
“Exposing force”: the COVID-19 pandemic and women's sport in Ireland during 2020–2021
Authors: Crosson Seán , Ní Chumhaill Maedhbh
Published: July 2023

Introduction

An analysis of how the pandemic served to highlight neglected weaknesses and inequalities with regard to the structures and supports available to facilitate women's sport in Ireland.

Methods

A survey conducted in the summer of 2021 with 194 female athletes across the island of Ireland. These athletes were engaged with the sports of camogie, Ladies Gaelic football, hockey, and rugby, and each responded to a 28-question survey.

Results

Our findings indicate that the experiences of female athletes during the COVID-19 pandemic raise serious questions regarding equality in sport across gender lines. Concerns expressed by the surveyed athletes, especially in relation to access to facilities, inadequate sponsorship, and funding reveal salient aspects of the experiences of Irish female athletes during the pandemic, and its role as an “exposing force” of inequalities within Irish sport.

Conclusion

The COVID-19 pandemic in Ireland has been a challenging and revealing period with regard to sport in Ireland, acting as an “exposing force” of the existing inequitable structures for both the support and coverage of women's sport. Such challenging periods can also offer opportunities to learn, progress and improve and already in the past year there is evidence of positive developments for women's sport in Ireland, developments that we contend were expedited due to the impact of the COVID-19 pandemic in Ireland.
European Society of Organ Transplantation (ESOT) Consensus Statement on Prehabilitation for Solid Organ Transplantation Candidates
Authors: Annema Coby , De Smet Stefan , Castle Ellen M. , Overloop Yasna , Klaase Joost M. , Janaudis-Ferreira Tania , Mathur Sunita , Kouidi Evangelia , Perez Saez Maria Jose , Matthys Christophe , Dobbels Fabienne , Ferrari Pisana , Gołębiewska Justyna , Mrzljak Anna , Girman Peter , Perch Michael , Lopez-Lopez Victor , White Colin , Koval Dmytro , Greenwood Sharlene , Monbaliu Diethard
Published: July 2023

There is increasingly growing evidence and awareness that prehabilitation in waitlisted solid organ transplant candidates may benefit clinical transplant outcomes and improve the patient’s overall health and quality of life. Lifestyle changes, consisting of physical training, dietary management, and psychosocial interventions, aim to optimize the patient’s physical and mental health before undergoing surgery, so as to enhance their ability to overcome procedure-associated stress, reduce complications, and accelerate post-operative recovery. Clinical data are promising but few, and evidence-based recommendations are scarce. To address the need for clinical guidelines, The European Society of Organ Transplantation (ESOT) convened a dedicated Working Group “Prehabilitation in Solid Organ Transplant Candidates,” comprising experts in physical exercise, nutrition and psychosocial interventions, to review the literature on prehabilitation in this population, and develop recommendations. These were discussed and voted upon during the Consensus Conference in Prague, 13–15 November 2022. A high degree of consensus existed amongst all stakeholders including transplant recipients and their representatives. Ten recommendations were formulated that are a balanced representation of current published evidence and real-world practice. The findings and recommendations of the Working Group on Prehabilitation for solid organ transplant candidates are presented in this article.
RNA 3D Structure Prediction: Progress and Perspective
Authors: Wang Xunxun , Yu Shixiong , Lou En , Tan Ya-Lan , Tan Zhi-Jie
Published: July 2023

Ribonucleic acid (RNA) molecules play vital roles in numerous important biological functions such as catalysis and gene regulation. The functions of RNAs are strongly coupled to their structures or proper structure changes, and RNA structure prediction has been paid much attention in the last two decades. Some computational models have been developed to predict RNA three-dimensional (3D) structures in silico, and these models are generally composed of predicting RNA 3D structure ensemble, evaluating near-native RNAs from the structure ensemble, and refining the identified RNAs. In this review, we will make a comprehensive overview of the recent advances in RNA 3D structure modeling, including structure ensemble prediction, evaluation, and refinement. Finally, we will emphasize some insights and perspectives in modeling RNA 3D structures.
Synthesis and Biological Evaluation of Resveratrol Methoxy Derivatives
Authors: Fragopoulou Elizabeth , Gkotsi Katerina , Petsini Filio , Gioti Katerina , Kalampaliki Amalia D. , Lambrinidis George , Kostakis Ioannis K. , Tenta Roxane
Published: July 2023

Resveratrol, a naturally occurring stilbene, exhibits numerous beneficial health effects. Various studies have demonstrated its diverse biological actions, including anti-oxidant, anti-inflammatory, and anti-platelet properties, thereby supporting its potential for cardio protection, neuroprotection, and anti-cancer activity. However, a significant limitation of resveratrol is its weak bioavailability. To overcome this challenge, multiple research groups have investigated the synthesis of new resveratrol derivatives to enhance bioavailability and pharmacological activities. Nevertheless, there are limited data on the effects of resveratrol derivatives on platelet function. Therefore, the objective of this study was to synthesize resveratrol methoxy derivatives and evaluate their anti-platelet and anti-proliferative activity. Platelet-rich plasma (PRP) obtained from healthy volunteers was utilized to assess the derivatives’ ability to inhibit platelet aggregation induced by platelet activating factor (PAF), adenosine diphosphate (ADP), and thrombin receptor activating peptide (TRAP). Additionally, the derivatives’ anti-tumor activity was evaluated against the proliferation of PC-3 and HCT116 cells. The results revealed that some methoxy derivatives of resveratrol exhibited comparable or even superior anti-platelet activity compared to the original compound. The most potent derivative was the 4′-methoxy derivative, which demonstrated approximately 2.5 orders of magnitude higher anti-platelet activity against TRAP-induced platelet aggregation, indicating its potential as an anti-platelet agent. Concerning in silico studies, the 4′-methyl group of 4′-methoxy derivative is oriented similarly to the fluorophenyl–pyridyl group of Vorapaxar, buried in a hydrophobic cavity. In terms of their anti-tumor activity, 3-MRESV exhibited the highest potency in PC-3 cells, while 3,4′-DMRESV and TMRESV showed the greatest efficacy in HCT116 cells. In conclusion, methoxy derivatives of resveratrol possess similar or improved anti-platelet and anti-cancer effects, thereby holding potential as bioactive compounds in various pathological conditions.
A Systematic Review on Biomass Treatment Using Microwave-Assisted Pyrolysis under PRISMA Guidelines
Authors: Syed Neyha Rubab , Zhang Bo , Mwenya Stephen , Aldeen Awsan Shujaa
Published: July 2023

Biomass as a renewable energy resource is a major topic on a global scale. Several types of biomass heat treatment methods have been introduced to obtain useful byproducts via pyrolysis. Microwaves are a practical replacement for conventional stoves and ovens to perform pyrolysis of biomass. Their rapid heating rate and user-friendliness make them a good choice for the pyrolysis process over conventional methods. The current study reviewed research articles that used microwaves for the pyrolysis process on different types of biomass. This study primarily provides comprehensive details about the pyrolysis process, especially microwave-assisted pyrolysis (MAP) and its feasibility for treating biomass. A systematic literature review, according to the PRISMA guidelines, was performed to find research articles on biomass treatment using MAP technology. We analyzed various research studies (n = 32), retrieved from different databases, that used MAP for pyrolysis on various types of biomass, and we achieved good results. The main goal of this study was to examine the usefulness of the MAP technique, comparing its effects on distinguished types of biomass. We found MAP’s effective parameters, namely, temperature, concentration of microwave absorber, moisture percentage of starting material and flow rate, microwave power and residence time of the initial sweep gas that control the pyrolysis process, and effect quality of byproducts. The catalytic agent in MAP pyrolysis was found to be useful for treating biomass, and that it has great potential to increase (nearly double) the production yield. Although MAP could not be used for all types of materials due to some challenges, it produced good results compared to conventional heating (pyrolysis) methods. We concluded that MAP is an effective method for reducing pyrolysis reaction time and improving the quality of value-added products. Also, MAP eliminates the shredding requirement for biomass and improves heating quality. Therefore, it is a viable method for reducing pyrolysis processing costs and should be applied on a larger scale than lab scale for commercialization.
Participation of Oxidative Stress in the Activity of Compounds Isolated from Eleutherine plicata Herb
Authors: Gomes Antônio Rafael Quadros , Cruz Jorddy Neves , Castro Ana Laura Gadelha , Cordovil Brigido Heliton Patrick , Varela Everton Luiz Pompeu , Vale Valdicley Vieira , Carneiro Liliane Almeida , Ferreira Gleison Gonçalves , Percario Sandro , Dolabela Maria Fâni
Published: July 2023

From Eleutherine plicata, naphthoquinones, isoeleutherine, and eleutherol were isolated, and previous studies have reported the antioxidant activity of these metabolites. The present work evaluated the role of oxidative changes in mice infected with Plasmodium berghei and treated with E. plicata extract, fraction, and isolated compounds, as well as to verify possible oxidative changes induced by these treatments. E. plicata extracts were prepared from powder from the bulbs, which were submitted to maceration with ethanol, yielding the extract (EEEp), which was fractionated under reflux, and the dichloromethane fraction (FDMEp) was submitted for further fractionation, leading to the isolation of isoeleutherine, eleutherine, and eleutherol. The antimalarial activity was examined using the suppressive test, evaluating the following parameters of oxidative stress: trolox equivalent antioxidant capacity (TEAC), thiobarbituric acid reactive substances (TBARS), and reduced glutathione (GSH). Furthermore, the molecular docking of naphthoquinones, eleutherol, eleutherine, and isoeleutherine interactions with antioxidant defense enzymes was investigated, which was favorable for the formation of the receptor–ligand complex, according to the re-rank score values. Eleutherine and isoeleutherine are the ones with the lowest binding energy for catalase (CAT), glutathione reductase (GR), and glutathione peroxidase (GPx1), showing themselves as possible targets of these molecules in the involvement of redox balance. Data from the present study showed that treatments with E. plicata stimulated an increase in antioxidant capacity and a reduction in oxidative stress in mice infected with P. berghei, with naphthoquinones being responsible for reducing oxidative changes and disease severity.
Fourier Transform Mid-Infrared Spectroscopy (FT-MIR) as a Method of Identifying Contaminants in Sugar Beet Production Process—Case Studies
Authors: Gruska Radosław Michał , Kunicka-Styczyńska Alina , Jaśkiewicz Andrzej , Baryga Andrzej , Brzeziński Stanisław , Świącik Beata
Published: July 2023

Food safety has received considerable attention in recent years. Methods for rapid identification of a variety contaminants in both the final product and the manufacturing process are constantly developing. This study used Fourier Transform Mid-Infrared Spectroscopy (FT-MIR) spectroscopy to identify various contaminants endangering white sugar production. It was demonstrated that inorganic compounds (calcium carbonate—CaCO3), plastic contaminants (polypropylene), and oily contaminants (compressor sealing and lubrication lubricant) can be identified with a high degree of precision. FT-MIR spectroscopy was proved to be a useful technique for detecting sugar contaminants rapidly and precisely even without the application of a sophisticated spectra analysis. Commercial databases of reference spectra usage significantly simplify and facilitate the application of this method.
Online hate and the contentious case of stirring up hatred offences
Authors: Gordon Benito Iñigo
Published: July 2023

In 2016, as requested, the UK Government submitted written evidence to the Home Affairs Committee's inquiry into hate crime and its consequences. Among all the offences listed as part of what was called a robust legal framework to combat online hate, there was one set of offences surprisingly missing. The stirring up hatred offences (ss. 18-23 and 29B-29G of the Public Order Act 1986), at least comparable to those envisaged in Article 510 of the Spanish Criminal Code (that is, punishable hate speech), were laid incomprehensibly out of play. Hence, this research study first aims to determine whether this decision is understandable. Then, we will focus on some legal hotspots concerning those offences to visualise better how they operate in practice. Finally, by way of conclusion, a comparative endeavour will be made with the Spanish legal system, bringing to the forefront the conflict points already dealt with.
The important accounting graduates skills for the Libyan job market: perceptions of academics and professionals
Authors: Abdalla Rezgalla
Published: July 2023

The purpose of this study is twofold. First, it aims to explore the important accounting graduate skills namely accounting technical skills, computer accounting skills, and general skills for the Libyan job market. Second, it aimed to investigate whether the opinions of academics and professionals are different regarding accounting technical skills, computer accounting skills, and general skills. The study used 100 questionnaires received from academics and professionals and used descriptive statistics, one sample t-test and independent samples t-test to test the hypothesis of the study. The findings showed that the selected accounting graduates’ skills particularly accounting technical skills, computer accounting skills, and general skills are important for the Libyan job market. Also, the results revealed no differences between the perceptions of academics and professionals regarding the important accounting graduate skills in the Libya job market.
Depresión e ideación suicida en estudiantes preparatorianos
Authors: Quevedo Martha , Salado Marisol
Published: July 2023

The objective of this study was to identify the levels of depression and suicidal thinking existing in the students of the Preparatory Academic Unit No. 13 of the UAGro. Jorge Bustos Aldama of Zihuatanejo, Gro. Mexico, to identify students who are at risk of committing suicide and to be able to channel them for proper care. A quantitative, descriptive and cross-sectional approach was followed, a Google form was applied that included the instruments: the Beck Depression Inventory II and the IS PATH WARM Scale. The population consisted of 407 students through a non-probabilistic sampling. Regarding the results; 51% of the students did not present any level of depression; while 18% of them presented levels of severe depression. Likewise, 55% of those examined showed medium or high suicidal risk and 9% presented very high suicidal risk, requiring hospitalization to preserve their lives and 40% of the participants showed low suicidal risk. This means that the mental health problems that young people present are worrisome and require that educational institutions, health institutions and the three levels of government have to implement actions for their attention and prevention.
Pengaruh Aktivitas Fisik Dan Kualitas Tidur Terhadap Prestasi Akademik Peserta Didik Fakultas Kedokteran UKRIDA Angkatan 2019
Authors: Botoor Maria Caecaelia , Susilowati Rina Priastini , Josephine Jodie
Published: July 2023

Tidur merupakan perilaku aktif yang dilakukan manusia secara terus-menerus dimana kualitas tidur menjadi tolak ukur seseorang dapat menikmati tidur dan mempertahankan kestabilan tubuhnya. Aktivitas fisik yang dilakukan secara konsisten dan rutin dapat memberi pengaruh yang besar tehadap keadaan fisik seseorang. Prestasi akademik adalah hasil belajar seorang peserta didik yang merupakan bagian terpenting dalam pendidikan. Penelitian ini menggunakan metode studi deskriptif kuantitatif, cross- sectional dengan mengambil data melalui kuesioner. Penelitian menunjukan peserta didik Angkatan 2019 memiliki kualitas tidur yang baik dan melakukan aktivitas fisik yang cukup. Dimana aktivitas fisik berpengaruh secara signifikan terhadap tingkat prestasi akademik dari mahasiswa Fakultas Kedokteran Ukrida Angkatan 2019. Berdasarkan uji parsial dengan nilai signifikansi 0,406 (>0,05) yang menunjukkan adanya pengaruh antara aktivitas fisik terhadap prestasi akademik. Berdasarkan uji parsial dengan nilai signifikansi 0,220 (>0,05) yang menunjukkan adanya pengaruh antara kualitas tidur terhadap prestasi akademik. Uji F merupakan pengujian terhadap koefisien regresi secara bersama-sama dengan membandingkan p-value dengan tingkat signifikansi tertentu.
Interferon Gamma sebagai Deteksi Awal Infeksi yang Disebabkan oleh Toxoplasma gondii
Authors: Monica Puspa Sari
Published: July 2023

Diagnosis dini infeksi Toxoplasma gondii penting untuk efektifitas pengobatan. Obat yang tersedia tidak dapat membunuh bradizoit yang terkandung dalam kista, obat tersebut hanya dapat membunuh pada stadium takizoit. Semakin cepat infeksi T.gondii terdeteksi maka semakin besar kemungkinan infeksi dapat dihentikan dan keberhasilan pengobatan tercapai. Saat ini tes serologi berbasis antibodi menjadi metode diagnostik yang paling sering digunakan untuk mendeteksi T. gondii. Namun, tes serologi diketahui memiliki beberapa keterbatasan. Berdasarkan penelitian terakhir, Interferon-gamma release assay (IGRA) yang merupakan pemeriksaan berbasis sel T diperkenalkan sebagai uji in vitro untuk mendeteksi infeksi T. gondii. Baik infeksi akut dan kronis bisa dideteksi dengan IGRA,  IGRA dapat mendeteksi infeksi pada hari ke 3, sementara serum IgM dan IgG terdeteksi pada hari ke 9 dan 13 pasca infeksi. IGRA secara akurat dapat membedakan individu yang terinfeksi dan yang tidak terinfeksi dengan menunjukkan aktivasi limfosit yang kuat setelah distimulasi secara in vitro oleh antigen T. gondii, bahkan pada hari pertama kehidupan. IGRA adalah suatu metode tes yang mudah dan murah untuk mengukur sel mediasi  imunitas terhadap T. gondii. Oleh karena itu, IGRA memiliki potensi untuk menjadi alat diagnostik deteksi dini untuk infeksi T.gondii.
Efektivitas Kompres Jahe pada Lanjut Usia Penderita Nyeri Osteoarthritis
Authors: Rumiati Flora , Meistika Gabriel , Heriyanto Heriyanto , William William
Published: July 2023

Kartilago pada lutut kaki semakin lama akan semakin menipis seiring dengan bertambahnya usia dan bertambahnya beban pada tumpuan kaki. Kartilago pada lutut disebut dengan meniscus yang berguna untuk melindungi tulang yang ada disekitarnya agar tidak saling bergesekan ketika bergerak. Ketika meniscus menipis dan saling bergesekan akan menimbulkan rasa nyeri dan bunyi krepitasi saat berjalan. Nyeri merupakan suatu keadaan yang tidak nyaman karena terjadi rangsangan fisik yang disalurkan ke otak diikuti dengan reaksi fisik hingga emosional. Osteoarhtritis merupakan penyakit sendi yang menyebabkan penurunan gerak sendi akibat adanya rasa nyeri. Gangguan sendi ini paling sering terjadi pada lutut. Terapi kompres jahe hangat akan membuat pembuluh darah melebar atau terbuka dan sirkulasi darah menjadi lancar. Metode pembuatan literature ini berupa pendekatan deskriptif yang mencari berbagai jurnal atau artikel penelitian dengan memiliki tema penelitian yang sama. Didapatkan hasil dengan 10 jurnal, dengan pembahasan yang sama. Dimana dalam beberapa jurnal mendapatkan hasil yang terbukti efektif. Dapat disimpulkan bahwa kompres jahe hangat efektif untuk mengurangi nyeri pada osteoarthritis.
Yılsonu Harcama Artışı (Aralık Ateşi) Bağlamında Bütçe Harcamaları Üzerine Tartışma
Authors: BEKTAŞ Nur Belkıs
Published: July 2023

Devlet bütçeleri genellikle bir yıllık süre ile sınırlıdır. Bütçenin yıllık olma ilkesi bağlamında kamu kurumları kendilerine tahsis edilen ödenekleri ancak mali yıl içinde harcayabilirler. Devlet bütçesi olarak hazırlanan merkezi yönetim bütçesinin gerçekleşmesinde yılın her ayına eşit dağıtılmış bir ‟ödenek harcamasının” olmadığı, özellikle ödeneklerin harcanmasında yılın son aylarına diğer aylara göre daha fazla yüklenildiği yerli ve yabancı literatürdeki çeşitli çalışmalarda ortaya konmuştur. Özellikle uluslararası çalışmalarda yılın son aylarına doğru gerçekleşen harcamaların etkin olmayan harcama profili oluşturduğu ifade edilmiş, bu durumun ortadan kaldırılması yönünde öneriler ortaya atılmış hatta ödeneklerin ertesi yıla devri gibi öneriler de getirilmiştir. Bu çalışmada ise aralık ateşi konusu Türkiye açısından ele alınmış ve Türkiye’deki bütçe ödeneklerinin hareketi harcama türü -cari, yatırım, transfer- temelinde incelenerek gerçekleşen durumun olağan mı? yoksa olağanüstü bir durum mu? olduğu üzerine bir tartışma yapılmıştır. Sonuç olarak bütçe teorisi ve ihale mevzuatı yönüyle aralık ateşi durumunun Türkiye’de özellikle yatırım harcamaları açısından olağan bir durum olduğu, gelecek yıla ödenek devri önerisinin ise Türkiye için genel bir uygulama olarak geçerli olamayacağı ancak karşılığı nakit bulunan ödeneklerde ve bütçe fazlasının verildiği dönemlerde bu önerinin geçerli olabileceği kanaati oluşmuştur.
LEVERAGING STRATEGIC MANEUVERABILITY TO AUGMENT BUSINESS MODEL INNOVATION FOR COMPETITIVE ADVANTAGE DURING ENVIRONMENTAL TURBULENCE
Authors: Mariam Shahida Mariam , Khawaja Kausar Fiaz Khawaja , Khan Hafiz Ghufran Ali Khan
Published: July 2023

ABSTRACT
 
Purpose: Ensuring that businesses thrive in turbulent environments is as challenging as navigating the proverbial stormy waters. Drawing upon attention-based and action-based views of firms’ dynamic capabilities, we examined whether firms with high strategic maneuverability can gain a competitive advantage in turbulent environments by adopting business model innovation.
The spiritual dimension of personality and its role in mental health
Authors:   Psychiatry Department, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania, Nirestean Aurel , Lukacs Emese ,   Psychiatry Clinic II,  “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania, Buicu Gabriela ,   Psychiatry Department, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania, Bilca Monica ,   Psychiatry Clinic II,  “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania, Pokorny Vasile ,   Brancovenesti Psychiatry Hospital, Brasov, Romania
Published: July 2023

The concept of mental health is a global concept and is complementary to psychiatry. That is also because psychiatry disorder is often a deformed and caricatured image of mental health. Both mental health and psychiatric disorders implies physical body, psychism, as well as spiritual dimension of personality. Both of them interfere with individual and collective biography, with community traditions and customs, as well as with cultural, religious, and moral values. In the mental health and personality approaches the dimensional perspective plays a major role. According to this perspective, personality dimensions favor those spiritual experiences that enhance the coping abilities, self-determination, and are representing a way of cultivating those virtues which protect the mental health and allow the human being to respect also those things and events which don't depend of it.
Depression screening at the primary care level – A cost-efficient intervention
Authors:   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Nica Raluca Ileana , Pirlog Mihail Cristian ,   Department of Psychiatry, University of Medicine and Pharmacy of Craiova, Romania
Published: July 2023

Over 350 million people worldwide suffer from depression, and it is one of the leading causes of disability across the globe (1, 2, 3, 4, 5). In Europe, approximately 21 million people are affected by depression out of a population of 446 million people. Depression places a burden not only on individuals but also on the society due to its impact on health, social and economic systems. Depression accounts for 1% of the GDP of Europe (8), and amounted to approximately 118 billion euros, which translates to approximately EUR 253 per inhabitant (8). Given the magnitude of the burden of depression, there is a need for efforts to be directed at early identification to improve recovery and enhance treatment outcomes and ideally, to prevent depressive symptoms from developing into a clinical depressive episode. Depression is considered as a common mental health disorder (CMHD) given its high prevalence and many people presenting with depressive symptoms often seek care from their primary care physician or general practitioner first, making the general practitioner an ideal gatekeeper for screening and detection and management of depression (6, 7, 26). Screening for depression at the primary care level can have a significant impact on early recognition and treatment, prevention of the development of more severe forms of depression, better adherence to treatment of chronic conditions, enhancement of recovery outcomes and consequently on the associated costs. According to the studies, despite the high prevalence of depression and the fact that many people experiencing depressive symptoms first come into contact with the health system through their primary care physicians, depression is in fact only identified in 30-50% of instances by primary care professionals (27,34). Early intervention is key as previous research shows that 20% of people who committed suicide visited a primary care physician in the month preceding the suicide (12, 35). The purpose of this review is to search based on the existing studies what are the recommendations regarding depression screening at the primary care level. At present, at the international level based on the existing studies is not a uniform opinion about recommending the screening at the primary care level for depression and about the criteria to be met for the depression screening at the primary care level that could lead to a cost-efficient intervention. It is still incipient the research regarding the efficiency of this intervention and the conditions in which it becomes cost-efficient.
An 81-year-old woman with nocturnal hallucinations due to Charles Bonnet syndrome
Authors:   “Prof. Dr. Alexandru Obregia” Psychiatric Hospital, Bucharest, Romania, Sopu Andreea
Published: July 2023

The presence of nocturnal hallucinations can be indicative of several underlying causes, one of which is represented by Charles Bonnet syndrome (CBS), a pathology characterized by the occurrence of nighttime hallucinations in the absence of visual stimuli. This condition predominantly affects elderly patients, with an average age range between 75 and 85 years old. However, this pathology is often underdiagnosed due to the lack of interdisciplinary cooperation and knowledge regarding this syndrome. The present article aims to highlight a case study of a patient who has been experiencing distressing nocturnal hallucinations for approximately 2 years. The patient was eventually diagnosed with visual impairments as the underlying cause of the hallucinations.