bluuebunny/crossref_metadata_2025 huggingface dataset:
Hedera helix (Wall Ivy) leaf ethanol extract shows cytotoxic and apoptotic effects in glioblastoma cells by generating reactive oxygen species
Authors: Yenigün Vildan Betül , Kocyigit Abdurrahim , Kanımdan Ebru , Durmus Ezgi , Koktasoglu Fatmanur
Published: December 2023

Aim: Glioblastoma, known for its aggressiveness, accounts for most malignant gliomas and the efficiency of its treatment is still not enough showing remarkably poor prognosis even though a complex treatment approach. Hedera helix is an evergreen plant mostly known for its effects on respiratory function, especially in chronic bronchial asthma, as well as its antimicrobial, anti-inflammatory, antioxidant, and potential antitumor properties, while its effect on glioblastoma cancer and the underlying mechanism has not been elucidated yet. The aim of this study was to examine the anti-cancer properties of Hedera helix (common ivy) in relation to its ability to induce cytotoxicity, apoptosis, and reactive oxygen species production in glioblastoma (U87) cells.
Material and Methods: The leaves’ ethanol, methanol, and water extracts were analyzed for phenol, flavonoid, and antioxidant levels through photometric methods. Then, different concentrations of ethanol extract were applied to U87 cells for 24 hours and analyzed for cytotoxic, apoptotic, and ROS-generating effects by measuring the luminometric intracellular ATP amount, Acridine Orange/Ethidium Bromide double staining, and DCFH-DA methods, respectively.
Results: Phenol, flavonoid, and antioxidant results of all three extracts show that ethanol was best for extraction. The results showed that Hedera helix ethanol extract had dose-dependent cytotoxic and apoptotic effects with increased intracellular ROS levels.
Conclusion: These results concluded that high doses of Hedera helix ethanolic extract may exhibit anti-cancer effects through pro-oxidant activity.
Thirty years in anesthesiology: A bibliometric analysis
Authors: Tümer Murat , Öztürk Talih , İzgi Murat , Yalçın Haydar
Published: December 2023

Background: The number of publications on anesthesiology continues to increase. Although there are studies conducted about this increase, they are insufficient to show the direction and structure of the changes. This study aimed to investigate the conceptual structure and thematic evolution in publications about anesthesiology over the last 30 years.
Methods: In this study we made a systematic reviews and bibliometric analyses of observational and Randomized Controlled Trial (RCT) studies. Bibliometric analysis was used to reveal thematic clusters by associating keywords and relationship patterns in three periods. Thematic clusters were revealed using a science mapping analysis based on co-word networks and strategic diagrams created according to centrality. Density values were used to determine the positions of the clusters. A total of 119,842 articles published between 1990 and 2022 in the anesthesiology category of the Web of Science (WOS) Core Collection were analyzed. Articles published before 1990 and/or not in the WOS Collection were excluded from the study.
Results: Seven thematic areas were identified over three time periods: Pain, Medications, Regional Anesthesia, Cardiovascular Anesthesia, Pediatric Anesthesia, Critical Care, and Airway Management. Over the years, motor themes have been shaped by new anesthetic agents and techniques. Pain and Regional Anesthesia have been the most researched topics. Patient Safety, Elderly Patients, and Palliative Care were the emerging themes in the last years. Critical Care thematic area moved to Mortality, Mechanical Ventilation, and COVID-19.
Conclusion: Pain is the most popular topic over the last 30 years. Increasing of themes like Patient Safety and Palliative Care in the last years may be related to the increasing quality management awareness and the older population. The fact that the COVID-19 thematic area has a large place in last period shows the effect of the pandemic in the field of anesthesiology.
The cytologic analysis of aqueous humor in eyes with uveitis
Authors: Özdamar Erol Yasemin , Kazancı Burcu , Kaya Pınar , Sabuncuoğlu Bizden , Bayrak Gözde , Karabacak Rukiye , Özdal Pınar
Published: December 2023

Purpose: The purpose of this study was to evaluate the cytologic analysis of aqueous humor (AH) of the eyes with Fuchs uveitis (FU) and idiopathic anterior uveitis (IAU).
Methods: AH of 25 uveitic eyes (12 FU and 13 IAU) were evaluated cytologically. The samples of the anterior chamber were taken before cataract surgery. Aqueous fluid samples were evaluated by applying a Giemsa stain.
Results: The 12 patients with FU and 13 patients with IAU were included in this study. In AH, the number of lymphocytes was similar in eyes with FU and IAU (the number of lymphocytes: min:1 and max:7). The acellular amorphous structures were detected in eyes with FU, and the same finding was not observed in the eyes with IAU. In addition, any pigmented cells or accumulation were not detected in any of the eyes.
Conclusion: The acellular amorphous structures were the remarkable finding of this study. It has been considered that amorphous structures in the AH of the eyes with FU could be related to chronic, low-grade anterior chamber inflammation and responsible for several complications of uveitis. FU is a uveitic entity with mysterious findings that await clarifications in its etiopathogenesis.
Management of social media as a Branding Tool by the Madrasah Aliyah Editorial Team
Authors: Ramadhani Khalilah , Setyowati Erna
Published: December 2023

This research aims to examine social media management as a way of branding at Madrasah Aliyah Negeri (MAN) Batu City by a special team called the Editorial Team, which is made up of public relations professionals. This study took a qualitative approach and conducted case study research. Data was gathered using interviews, observation, documentation techniques, and data analysis techniques applied in three steps: data condensation, data presentation, and conclusion. The data obtained is checked for the validity of the data using the triangulation technique. The findings show that MAN Batu City's branding is professionally carried out by the Editorial Team using social media, with due regard for the selection of publication techniques, targeting, and situation determination, as well as the time of publication during branding implementation. Branding is carried out ideally through the Editorial Team's orderly coordination of information management in partnership with online media to support suitable facilities and operate following their respective tasks.
Analisis kadar PM10 dan CO serta keluhan pernapasan pada petugas operasional terminal peti kemas PT PELINDO Belawan tahun 2023
Authors: Ramadhani Adinda Nur , Santi Devi Nuraini
Published: December 2023

Air pollution and respiratory symptoms among operational staff at container terminal of PT. PELINDO Belawan might be caused by emission of PM₁₀ and CO from operational container trucks. This research aims to assess PM₁₀ and CO levels, also to investigate respiratory symptoms among operational staff at container terminal of PT. PELINDO Belawan. This is an observational research with cross-sectional design study. From a population of 699 individuals, 88 samples were obtained using purposive sampling technique. Air quality data was collected through direct measurements at three different locations, while respiratory symptoms data was gathered through staff interviews. PM₁₀ level at the container terminal had exceeded the standard limit, with the highest concentration recorded at the entrance gate, reaching 193 µg/Nm³. Whereas, CO level remained within the acceptable range. Trucks flow observation over a week revealed that the highest flow occurred on Tuesday, with 3,037 trucks, while the lowest flow was on Sunday, with a total of 223 trucks. Among the 88 respondents, 40 individuals (45.5%) experienced respiratory symptoms, with the most common complaint, reported by 25 individuals (65%), being runny or congested nose. Most respiratory symptoms occurred at unpredictable times, as reported by 35 individuals (39.8%). Container terminal of PT. PELINDO Belawan is recommended to enforce mask usage while working and respiratory health check-ups regularly for the operational staff to monitor respiratory health of the operational staff, as well as planting trees to mitigate pollutant levels in the air.
A STRATEGIC APPROACH TO PERSONNEL MANAGEMENT OF ENTERPRISES
Authors:   National University «Lviv Polytechnic», Drymalovska Khrystyna
Published: December 2023

The company's activities, regardless of ownership, size, or other specific features, are carried out by the management in accordance with the overall development strategy. The development and implementation of an enterprise's overall development strategy are based on the identification and effective interaction of certain components. One of the most important components should be the personnel component. The human resources component of a business entity's strategy involves management's participation in reviewing proposals related to the implementation of measures to ensure effective personnel management in order to meet their primary and secondary requirements. Therefore, ensuring an effective human resources management system requires monitoring trends in the use of new models for the selection, development, motivation, and development of the enterprise's managed system. From now on, under the influence of the current business environment (challenges of the COVID-19 pandemic, military events), the issue of transforming the field of human resources management arises. Addressing this issue requires research and evaluation of a strategic approach to human resource management. The article highlights the essence of a strategic approach to human resources management. The main purpose of the study is to determine and substantiate the basic principles of the formation and implementation of a strategic approach to human resources management in today's conditions. As a result, the following tasks have been set: to characterize the personnel management system; to describe the main stages of ensuring a socially oriented mechanism of the personnel management system; to highlight the main advantages of effective personnel management; and to propose a definition of the essence of a strategic approach to personnel management. The article schematically presents the advantages of effective personnel management as a valuable capital. The reasons for actualizing the application of a strategic approach to personnel management are indicated. The main components of the formation and implementation of a human resource management strategy are indicated.
MEDICAL MARKETING: TRANSFORMATION OF PATIENT COMMUNICATION CHANNELS UNDER THE INFLUENCE OF THE COVID-19 PANDEMIC
Authors:   Sumy State University, Letunovska Nataliia , Ziabina Yevheniia ,   Sumy State University, Malyk Rostyslav ,   Sumy State University
Published: December 2023

The article raises the issue of transformational processes in medicine that took place under the influence of the coronavirus pandemic in 2020–2022. Today, the issue of the growing expectations of patients regarding the quality of medical services provided by healthcare institutions in Ukraine is topical. To improve the quality of services medical institutions offer, the authors propose marketing strategies and methods as essential components of competition in the medical market. The essence and central aspects of the use of offline and online marketing tools in the field of medicine were studied. The process of marketing activities by healthcare institutions is analyzed in detail. The list of marketing tools that have become the most in-demand on the market and which, under the influence of destabilizing factors, can equalize the effectiveness of their use to meet the needs of medical institutions and the interests of patients of these institutions is defined. In the article, medical marketing is considered an approach that allows forecasting the demand for medical services, expanding the range of services in response to changes occurring in the market under the influence of the pandemic and other destabilizing factors, and implementing appropriate marketing strategies. The main marketing elements in the need of medical services are market research, segmentation of the target audience, planning and implementation of marketing strategies, analysis of results, and adjustment of strategy. It is emphasized that the promotion of medical services can be carried out through various channels of interaction with patients: mass media, outdoor advertising and advertising in transport, television advertising, social networks, messengers, etc. The sales funnel in the medical services field has certain features compared to other services, which must be paid attention to when planning a strategy for promoting a medical product. Taking into account the transformational processes in the market, it makes it possible for medical institutions to attract more customers than competitors and increase their revenue, increasing their profitability.
BUSINESS RELOCATION IN THE CONDITIONS OF WAR
Authors:   V.N. Karazin Kharkiv National University, Mangushev Dmitry , Budris Tetyana ,   V.N. Karazin Kharkiv National University, Kalinichenko Vladyslav ,   V.N. Karazin Kharkiv National University
Published: December 2023

In the conditions of martial law, relocation is one of the main ways to ensure business continuity. In order to help domestic businesses move their economic activities to relatively safer territories, the Enterprise Relocation Program was developed, which provides for the provision of informational, logistical, and financial support. The article reveals the essence of relocation and its main types. The dynamics of domestic business relocation within the country, the structure of relocated business by relocation regions and industries are analyzed. It was established that the size and industry significantly influence the relocation of enterprises. Full relocation is characteristic mainly for small enterprises, while medium and large ones can usually carry out only a partial relocation. Thus, large enterprises, in particular, heavy industry, need access to sources of raw materials, large production areas, transportation of very large and complex equipment. State relocation support programs should focus on such enterprises. It is estimated how quickly relocated enterprises manage to resume their economic activity. Among those enterprises that have resumed their activities, trade enterprises and enterprises of the processing industry predominate, which together make up 71% of all relocated. Using the example of the IT sector, the factors that influence relocation and the reasons that limit it are analyzed in more detail. Relocation of enterprises is accompanied by a number of risks, including the high and often unpredictable actual amount of relocation costs, organizational and technical complexity of relocation, especially of property, limited opportunities to export all necessary assets, difficulties with areas for locating production; the likely high cost of renting production premises at the new location and with the selection of qualified personnel at the new location after the move, therefore it is especially important to retain the key composition of employees, ensuring their relocation to the new location and providing comfortable living and working conditions; loss of counterparties, suppliers of raw materials, etc., the need to find new ones, which requires additional financial costs and some time, which can lead to the failure of the enterprise.
PRINCIPLES OF FORMING A MARKETING STRATEGY IN THE PROCESS OF MANAGEMENT A TOURISM ENTERPRISE
Authors:   Ivan Franko National University of Lviv, Mandiuk Nazarii , Bilous Sofiia ,   Ivan Franko National University of Lviv
Published: December 2023

The article considers the specifics of developing a marketing strategy as a means of ensuring sustainable economic development of a tourism enterprise. The principles of marketing strategy formation are presented. The problem of proper formation of the marketing strategy is raised, which requires setting appropriate goals and objectives, the implementation of which in specific market conditions will lead to the achievement of the general corporate goals. Attention is drawn to the importance of harmonizing the interests of three stakeholders - the tourism enterprise, consumers and the public. Thus, when building an effective marketing strategy, a tourism company should rely on its own goals, available resource potential, the specifics of the tourism market, consumer needs and public interests. Great importance is attached to setting marketing goals of a tourism enterprise as a mandatory element of marketing management. Attention is drawn to the subordinate position of marketing goals in relation to the general goals of a tourism enterprise, which are the means of achieving them. The goals that form the basis of the marketing strategy relate to two aspects of the enterprise, namely products and markets, and also include the goals of product policy, pricing policy, distribution policy and communication policy. The specifics of forming a marketing strategy are considered, taking into account the product-market matrix of a tourism enterprise. The essence and importance of the marketing strategy, as well as its components, are revealed. An important role is assigned to market segmentation, identification of target markets, positioning of the tourism product, determination of competitive advantages of the tourism enterprise. The principles and requirements for the formation of a marketing strategy of a tourism enterprise are considered, compliance with which should ensure the effective implementation of marketing functions and tasks. Attention is drawn to the complexity and multifacetedness of the process of developing a marketing strategy, which requires taking into account the general goals of a tourism enterprise, the state of the external marketing environment, the capabilities of the enterprise, and the degree of risk.
TALENT MANAGEMENT AS A FACTOR INCREASING THE LEVEL OF ORGANIZATION DEVELOPMENT
Authors:   Taras Shevchenko National University of Kyiv, Narodovska Julia , Poltoratska Alona ,   Taras Shevchenko National University of Kyiv
Published: December 2023

The paper examines the essential characteristics of "talent management" as a factor in increasing the level of development of modern organizations. Essential characteristics and main approaches to defining the talent management category are analyzed. Features of the talent management system in modern organizations have been formed. The characteristics of the application of talent management in practice are given. The main mechanisms, methods and approaches to talent management at the enterprise are considered. The study showed that when working with talents, it is necessary to pay attention to the following characteristics: ambitions, which reflect the readiness of the employee to occupy management positions and perform critical roles; the desire to grow and develop; the opportunity to improve skills, knowledge, skills, experience and other essential characteristics; involvement, which shows the desire and ability of the employee to participate in the development of the enterprise and the achievement of the set goals. Scientific approaches to defining the essence of the "talent management" category have been studied. Features of the formation of the enterprise's talent management system are proposed. The characteristics of the application of talent management in practice are given. The main stages of talent management were analyzed and systematized: attraction, development, own management and evaluation of the effectiveness of the talent management system in companies. Scientific approaches to defining the concept of "talent management" have been studied. The main obstacles to introducing the talent management system in modern organizations have been identified. Talented employees are considered a factor in increasing the level of the company's development. The need to attract talent to increase competitiveness in modern international and national markets has been demonstrated. It is noted what influence talents have on the success of the enterprise. The experience of talent retention in the world's leading organizations is given, and an analysis of the talent management system and its impact on the organization is given using advanced analysis and research resources. The practice of attracting talent among the world's leading companies is highlighted.
ASSESSMENT OF THE EFFICIENCY OF LOGISTICS ACTIVITIES OF AN INDUSTRIAL ENTERPRISE
Authors:   Ukrainian State University оf Science аnd Technologies, Semenova Tetіana , Alieksieienko Mykyta ,   Ukrainian State University оf Science аnd Technologies
Published: December 2023

The article is devoted to the actual issues of evaluating the efficiency of logistics activities of an industrial enterprise. The main methodical approaches for assessing the efficiency of logistics activities of enterprises in modern conditions are presented and characterized. Usage of an improved methodology is proposed and substantiated for assessing the efficiency and reliability of logistics activity. The methodology for evaluating efficiency and reliability is based on the analysis of the structure of logistics costs in relation to profit. Profit is calculated by allocating them according to the articles of the financial results report: general production costs, administrative costs and sales costs. Logistics costs include costs for logistics administration and material flow management as part of administrative costs. Logistics costs include warehouse costs, transportation costs, and loading/unloading costs as part of sales costs. Logistics costs include supply costs, production logistics costs and service costs as part of general production costs. The methodology takes into account the peculiarities, influencing factors and other factors of the industrial enterprise. It is proposed to use indicators for a comprehensive assessment of the efficiency of the logistics system by its elements (supply, production, transportation, storage, marketing). The complex indicator is calculated for the efficiency of the logistics activity of the enterprise according to the formula of the geometric mean. The integral indicator of the efficiency of the logistics activity of the enterprise is calculated as the geometric mean of the integrated indicator of the efficiency of the logistics activity over the years of research. It is expedient to assess the reliability of the enterprise's logistics activities for each group of indicators using the coefficient of variation. The higher the rate of variation, the less reliable a particular logistics system is. An assessment of the efficiency and reliability of logistics activities at a specific industrial enterprise was carried out using the proposed methodology.
THE CURRENT STATE AND PRIORITY DIRECTIONS OF THE RECOVERY OF THE BANKING SECTOR OF UKRAINE IN THE POST-WAR PERIOD
Authors:   Vinnytsia Trade and Economic Institute of the State Trade and Economic University, Movchan Diana , Abdullaieva Anastasiia ,   Vinnytsia Trade and Economic Institute of the State Trade and Economic University
Published: December 2023

In recent years, the banking system of Ukraine has been operating and developing under extremely difficult circumstances. On the one hand, the banking market of Ukraine needs to develop and keep up with world trends in order to meet the conditions of joining the EU, and on the other hand, to face the challenges of today and support the national market in the conditions of active hostilities on the territory of Ukraine. With the beginning of a full-scale invasion, the Central Bank of Ukraine faced a number of important tasks: maintaining the economy and the population in a balanced state, conducting an effective monetary policy, the stability of the monetary unit in wartime conditions, and getting rid of banks with a Russian share in their capital. In view of recent years, a characteristic feature of the banking system of Ukraine is the fluctuation of its main financial indicators. In order to carry out an analysis, to identify critical problems and directions for their solution, it is first necessary to consider the current state of the banking system of Ukraine and the main reasons for the impact on changes. It is necessary not to forget the importance of analysis in dynamics, the causes of fluctuations and the effectiveness of already implemented actions. The purpose of the study is to analyze the current state of the banking system of Ukraine, to diagnose the causes of changes in the dynamics of the main indicators and to identify directions for the recovery of the banking sector of Ukraine in the post-war period. The article is devoted to the current state and priority areas of recovery of the banking sector of Ukraine in the post-war period. The article examines the dynamics of the number of banks in Ukraine and their structural divisions over the past 5 years, indicating the factors influencing the changes. The dynamics of assets and liabilities of the banking sector of Ukraine for the period 2019–2023 were considered and the main reasons for the changes were identified. The credit portfolio of the banking sector of Ukraine was analyzed. The dynamics of changes in the profitability of assets and capital of Ukrainian banks over the past 5 years were studied. The article outlined the current state of the banking sector of Ukraine for the period 2019–2023 based on the conducted research. The article highlights the priority areas of recovery of the banking sector of Ukraine in the post-war period. Appropriate conclusions were drawn from the conducted research. The following methods were used in the article: analysis, comparison, comparison, systematization, synthesis, description of facts and influencing factors.
DEVELOPMENT OF THE FINANCIAL MARKET OF UKRAINE
Authors:   Lviv Polytechnic National University, Moroz Nataliia
Published: December 2023

The article examines trends and prospects for the development of the financial market of Ukraine. Banks have a significant share of the assets of the entire market and play a significant role in it. State ownership in the banking sector prevails. Credit risk remains the determining factor among other types of risks; however, the recovery of the economy will gradually reduce credit risks. Over the past five years, the number of insurers, pawnbrokers and credit unions has more than doubled. The most numerous participants in the financial market are financial companies. The NBU softens the monetary policy, maintaining its ability to influence the behavior of economic agents, and strengthens the requirements for financial institutions, bringing them closer to European standards. Recommendations are given for financial institutions: compliance with prudential requirements of the regulator, timely reporting, revival of lending with improvement of credit risk management, improvement of compliance management, perfecting of cyber protection systems and improvement of business models.
THE ESSENCE AND CLASSIFICATION OF INCOME OF THE AGRICULTURAL ENTERPRISE
Authors:   Dnipro State Agrarian and Economic University, Zaluzhnya Alyona
Published: December 2023

The main goal of the activity of any enterprise is to obtain the maximum profit, which cannot be realized without obtaining the necessary level of income. The income of the enterprise, regardless of the field of activity, form of ownership and other factors, is of exceptional importance not only for a separate subject of entrepreneurial activity, but also for the economy as a whole. The article examines the main approach to determining the income of an enterprise in the legal framework and modern scientific sources, identifies its shortcomings, and proposes clarification of the definition. we believe that it is advisable to supplement the definition in the legal framework with a clarification – without taking into account the factor of unprofitability of the enterprise. As for the income of the agricultural enterprise, it is necessary to point out its main features. The first feature of the formation of the income of an agricultural enterprise is that it includes not only directly the income from the sale of agricultural products, but also the results of the assessment of the initial value of biological assets and the growth of their fair value. The second feature is that the amount of income of an agricultural enterprise is influenced by the seasonality factor, especially in the field of crop production. The third feature of the formation of income of agricultural enterprises is that it is often recognized before the sale of agricultural products directly after their production. As a fourth feature, it should be pointed out that agricultural products, in respect of which income is recognized, may be transferred to the category of expenses in subsequent reporting periods. Classification characteristics of income are summarized and the dynamics of incomes of agricultural enterprises in different sections are analyzed. A clear and logical structure of income classification makes it possible to organize an effective system of their accounting. The study of the peculiarities of the formation of incomes of agricultural enterprises provides grounds for the conclusion of the need for further research and improvement of the process of formation of incomes of enterprises with a seasonal nature of production. In particular, in the accounting of the income of agricultural enterprises, it is necessary to take into account the time factor caused by the peculiarities of seasonal production, when applying the principle of accrual and correspondence of income and expenses.
СУЧАСНІ ПОГЛЯДИ НА ВИНИКНЕННЯ СИНДРОМУ ЕМОЦІЙНОГО ВИГОРАННЯ В МЕДИЧНИХ ПРАЦІВНИКІВ: ОГЛЯД ЛІТЕРАТУРИ
Authors: Голованова І. А. , Хорош М. В. , Ляхова Н. О. , Бєлікова І. В. , Краснова О. І. , Подвін А. М. , Sakhniuk Sybina Oleksandrivna
Published: December 2023

Анотація. Актуальність. Специфіка професії медичного працівника вимагає високої психічної стійкості, відповідальності за життя і здоров'я людей, здатності працювати в екстремальних умовах, постійного емоційного напруження. Ці чинники можуть призвести до психічного виснаження, втрати працездатності та виникнення синдрому емоційного вигорання, тому розгляд факторів, що зумовлюють формування цього явища, є актуальним. Мета і завдання. Вивчити та проаналізувати особливості виникнення та прояву синдрому емоційного вигорання. Матеріали та методи. Методи: бібліосемантичний та історичний. Матеріали: опрацьовано 140 вітчизняних та зарубіжних літературних джерел та електронних ресурсів. Результати дослідження. Наразі немає чіткого розуміння сутності синдрому «вигорання», який відзначається як складне багатокомпонентне явище, що включає понад 100 симптомів. Численні публікації присвячені факторам ризику його виникнення, можна виділити три групи змінних, які мають певний вплив на розвиток цього синдрому в професіях «людина-особа»: особистісні, рольові та корпоративні (професійно-організаційні). У результаті аналізу літератури слід зазначити, що на сьогодні виділяють декілька моделей його розвитку. − однофакторна модель, яка визначає емоційне вигорання як стан фізичного, емоційного та психічного виснаження. − двофакторна модель, у якій вигорання складається з виснаження і деперсоналізації. − трифакторна модель, вигорання складається з емоційного виснаження, деперсоналізації, зниження особистих досягнень; − чотирифакторна модель, вигорання складається з емоційного виснаження, деперсоналізації професійної діяльності, деперсоналізації суб’єктів професійної діяльності, зниження особистих досягнень. Висновки. Синдром емоційного вигорання характеризується сукупністю факторів психічної, соматичної та соціальної сфер життя. Дослідження, присвячені цій проблемі, представлені в літературі досить широко, але на сьогодні відсутні певні клініко-психологічні та медичні технології, спрямовані на профілактику цього синдрому.
ХРОНІЧНИЙ КАЛЬЦІФІКУЮЧИЙ ТЕНДИНІТ РОТАТОРНОЇ МАНЖЕТИ ПЛЕЧОВОГО СУГЛОБА: УДАРНО-ХВИЛЬОВА ТЕРАПІЯ ЯК МЕТОД ВИБОРУ В АМБУЛАТОРНИХ УМОВАХ
Authors: Худецький Ігор Юліанович , Бучинський Олексій Сергійович
Published: December 2023

Актуальність. Кальцифікуючий тендиніт ротаторної манжети плеча (КТ РМП) характеризується великою популяційною поширеністю і впродовж місяців може залишатись резистентним до консервативного лікування. Одним з перспективних напрямків є екстракорпоральна ударно-хвильова терапія, яка сьогодні посідає визначне місце у системі надання допомоги пацієнтам з больовими синдромами опорно-рухового апарату. Матеріали та методи. Здійснено аналітичний огляд літературних джерел у базі даних PubMed. Результати. КТ РМП діагностується у 10–42% населення, передусім жінок у віці 20-50 років, і є однією з головних причин хронічного болю у плечі. Розвиток КТ РМП проходить кілька клініко-патогенетичних стадій: прекальцифікації, кальцинізації та репарації. КТ РМП добре діагностується рентгенографічним або ультразвуковим дослідженням. Запропоновано ряд лікувальних тактик без доказів переваги якоїсь конкретної з них. Обґрунтовано застосування екстракорпоральної ударно-хвильової терапії (ЕУХТ) у пацієнтів з важкими та стійкими симптомами КТ РМП. Встановлено, що ЕУХТ може значно зменшити болі, поліпшити функцію плечового суглоба і якість життя, зменшити розміри кальцифікації порівняно з консервативними методами лікування. Ряд систематичних оглядів та мета-аналізів показав, що ЕУХТ значно покращувала показники за шкалою Constant–Murley та інтенсивність болю у порівнянні з іншими методами та/або плацебо. Показано, що високоенергетичний протокол ЕУХТ має переваги перед низькоінтенсивним. Висновки. Кальцифікуючий тендиніт ротаторної манжети плеча (КТ РМП) слід визнати актуальною патологією опорно-рухового апарата. Аналіз даних літератури свідчить про високу ефективність екстракорпоральної ударно-хвильової терапії (ЕУХТ) при данії патології та необхідність впровадження цього методу в протоколи лікування в амбулаторних умовах.
СУЧАСНИЙ ПОГЛЯД НА ХРОНІЧНИЙ НЕСПЕЦИФІЧНИЙ М’ЯЗОВИЙ БІЛЬ У СПИНІ
Authors: Чоповський Дмитро Петрович
Published: December 2023

Мета – ретельне вивчення та аналіз факторів розвитку хронічного неспецифічного болю у спині, а також методів його діагностики та ефективного впровадження фізичної терапії. Методи дослідження. Для досягнення цілей був проведений теоретичний аналіз, що включав у себе узагальнення, синтез, порівняння та аналіз наявних результатів дослідження у сучасній науковій та методичній літературі. Результати дослідження. За результатами спостережень та огляду науково-методичної літератури хронічний неспецифічний м’язовий біль (ХНБС) у спині є складною і розповсюдженою проблемою здоров’я, що суттєво впливає на якість життя багатьох людей. Хронічний неспецифічний м’язовий біль у спині представляє собою тривалий або регулярний дискомфорт, що виникає в м’язах спини та може існувати без конкретної ідентифікованої патології чи основного захворювання, яке може пояснити цей біль. Цей стан може викликати неприємні відчуття, м’язову напругу та обмежити можливість фізичної активності, маючи значний вплив на якість життя пацієнта. Психосоціальні фактори відіграють суттєву роль у впливі на функціональність особи, якість її життя і обмежують її щоденну активність, що може сприяти зниженню продуктивності та частим періодам тимчасової непрацездатності. Ці фактори також впливають на результати фізіотерапевтичного втручання та мають значення для прогнозу у даного контингенту. Незважаючи на велику кількість досліджень у даній галузі, багато аспектів цієї проблеми залишаються недостатньо вивченими та неоднозначними. Наукова стаття присвячена огляду сучасних досліджень щодо хронічного неспецифічного м’язового болю у спині. В ній розглядаються питання патогенезу, факторів ризику, методів діагностики та доступних стратегій фізичної терапії. Проаналізовані результати останніх наукових досліджень сприяють поглибленню нашого розуміння механізмів виникнення болю та сприяють розробці більш продуктивних методів лікування. Окрім того, розглядаються психосоціальні аспекти впливу на розвиток хронічного неспецифічного м’язового болю у спині. Висновки. Аналіз наукової та науково-методичної літератури підтверджує, що біль у спині є поширеною проблемою, який значно впливає на якість життя хворих. Аналіз досліджень свідчить, що відновлення забезпечується завдяки правильно організованій і ефективній терапії.
САНІТАРНО-ГІГІЄНІЧНА ОЦІНКА ВЛАШТУВАННЯ «СОЛЯНИХ КІМНАТ»
Authors: Маненко Алек Костянтинович , Шипелик Юрій Петрович , Гущук Ігор Віталійович , Ткаченко Галина Михайлівна , Касіян Ольга Петрівна , Данилишин Надія Іванівна , Закаляк Наталія Романівна , Сидурко Мирослава Мирославівна , Козова Надія Ярославівна , Головацька Жанна Євгенівна
Published: December 2023

Анотація. Актуальність. Перед фахівцями Міністерства розвитку громад, територій та інфраструктури України, Міністерства охорони здоров’я України, Міністерства захисту довкілля та природних ресурсів України, експертами ДП «Укрдержбудекспертиза» і його обласних філій та іншими організаціями у зв’язку з повною відсутністю нормативно-технічної документації для влаштування «соляних кімнат» постає актуальна необхідність вирішення проблеми розроблення санітарно-гігієнічних та епідеміологічних вимог на підґрунті нормативів ISO, GMP, GLP для проєктів «соляних кімнат»галоаерозольної терапії, які на теперішній час відсутні. Всі проєктні організації розробляють замість проєктів лише калькуляцію цін на влаштування «соляних кімнат», а всі ДБН, ДСП ігнорують факт їх влаштування (будівництва). Тому, починати слід з закладання підвалин культури проєктування шляхом внесення доповнень у державні будівельні норми та санітарні правила. Матеріали та методи. Об’єктом дослідження є матеріали влаштування більш як 300 «соляних кімнат» в Україні, Європі, Китаї, Катарі, В’єтнамі, тощо, які надано ТзОВ «ВЕДІС» ЛТД (м. Луцьк), яке займається будівництвом «соляних кімнат», з пропозиціями щодо оцінки лікувальних факторів галоаерозольної терапії. Шлях насичення повітря «соляних кімнат» а відповідно організму пацієнтів викокодисперсним аерозолем NaCl рекомендується за допомогою галогенератора та допоміжних факторів. Результати дослідження. Гігієнічна і санітарно-епідеміологічна оцінка матеріалів влаштування «соляних кімнат» виявила недоліки, яких не повинно було б бути, якби в діючих ДБН та СанПіН були затверджені санітарно-гігієнічні та екологічні вимоги з врахуванням міжнародних стандартів. На виявлені недоліки були розроблені пропозиції щодо розроблення проєктів «соляних кімнат» галоаерозольної терапії, що сприятиме поліпшенню їх влаштування та експлуатації.
Cross gain modulation in quantum dot semiconductor optical amplifiers under the influence of the Probe
Authors: Flayyih Ahmed , Seyedeh Hamideh Kazemi  , Al-Khursan Amin
Published: December 2023

The Pulse effect on the  cross-gain modulation (XGM) in the quantum dot (QD) semiconductor optical amplifiers (SOAs) is investigated using the combining of the SOA power with the QD rate equations system. The QDs structure  includes  three regions: ground state (GS), excited state (ES) and wetting layer (WL). Thus, a set of rate equations for pump and probe signals is introduced for both steady-state and small-signal power values, which are solved numerically. The pulse shape was included in the analysis, for pump and probe signals.  The theoretical results showed a good agreement with the experimental results. It was found that decreasing pulse width of pump/probe ratio is efficient to increase XGM efficiency and bandwidth.
Gen Z: Obstacles, Ease and Strategies for Implementing the Values of the Quran at Islamic State University
Authors: Rahmah Rafiqah Dwi , Ratnasari Dwi , Mujahid Mujahid
Published: December 2023

Nowadays, the productive age is dominated by Generation Z, which is an all-digital generation. Practicing the teachings of Islam in modern times with its ease is a problem for Generation Z. The discussion of this study reveals the obstacles, conveniences and strategies that Gen Z does in carrying out religious teachings. The discussion in this study reveals the obstacles, conveniences and strategies that Gen Z does in carrying out religious teachings. Therefore, the researcher made this study to find out the understanding of the religious values of generation Z and how to maintain the religious values of generation Z in the Qur'anic approach. The research method used is qualitative research which is critically described. Then using data collection techniques through semi-structured interview sessions while still making question guidelines. This research is a case study conducted on students of the Faculty of Science and Technology Physics Study Program at UIN Sunan Kalijaga Yogyakarta. The interviewees consisted of two Physics Study Program students. The data analysis technique in this study uses triangulation techniques so that the results of this study are richer with scientific treasures in it. The results of this study indicate that Generation Z's understanding of religious values is Iman, Islam, Ihsan, Taqwa and Tawakal. Then the way generation Z maintains its religious values by making commitments to themselves, choosing good friendships, maximizing existing resources as a medium to remind themselves, understanding how the world of social media works and managing emotions well. The efforts made in facing various obstacles, conveniences and strategies are a form of self-serving to Allah by making the Qur'an as a guide to life.
Hubungan Antara Lama Menstruasi Dengan Kadar Hemoglobin Pada Mahasiswi Fakultas Kedokteran Universitas Muslim Indonesia Angkatan 2016
Authors: Dahlia Dahliah , Dewi Citra , Rasfayanah Rasfayanah , Yusriani Yusriani
Published: December 2023

Hemoglobin merupakan komponen penting dalam darah. Jika darah kekurangan hemoglobin atau jumlah hemoglobin dalam darah kurang dari jumlah normalnya, maka tubuh akan mengalami anemia.Tujuan daripenelitian ini adalah untuk menentukan hubungan antara lama menstruasi dengan kadar hemoglobin pada mahasiswi. Penelitian ini merupakan penelitian analitik deskriptif, pendekatan cross-sectional, menggunakan teknik Total Sampling. Sampel berjumlah 99 orang di Fakultas Kedokteran UMI. Pengumpulan data dilakukan dengan menggunakan kuisioner dan mengukur hemoglobin responden. Analisa data menggunakan uji spearman. Jumlah sampel sebanyak 99 mahasiswi, terdapat 49 mahasiswi (49,5%) yang mengalami lama menstruasi normal dengan kadar hemoglobin yang normal (≥12), terdapat 38 mahasiswi (38,4%) yang mengalami lama menstruasi normal dengan kadar hemoglobin rendah (<12), terdapat 3 mahasiswi (3,0%) yang mengalami hipermenorea atau lama menstruasi tidak normal dengan kadar hemoglobin normal (≥12), dan terdapat 9 mahasiswi (9,1%) yang mengalami menstruasi tidak normal (hipermenorea) dengan kadar hemoglobin rendah (<12), serta tidak ada mahasiswi yang mengalami hipomenorea. Berdasarkan hasil analisis uji hubungan diperoleh nilai p = 0,042 (lebih kecil dari nilai α = 0,05). Kesimpulan yang dapat diambil adalah terdapat adanya hubungan yang bermakna antara antara lama menstruasi dengan kadar hemoglobin pada mahasiswi Fakultas Kedokteran UMI angkatan 2016
PENGARUH BENTUK SEDIAAN EKSTRAK GONAD LANDAK LAUT (Diadema setosum) SEBAGAI PENYEMBUH LUKA BAKAR PADA KELINCI (Oryctolagus cuniculus)
Authors: Karmilah Karmilah , Badia Esti
Published: December 2023

Luka bakar adalah suatu bentuk kerusakan atau kehilangan jaringan yang disebabkan oleh kontak dengan sumber panas seperti api, air panas, bahan kimia, listrik dan radiasi. Gonad landak laut mengandung senyawa protein tinggi, flavanoid, triterpenoid, steroid, saponin, dan alkaloid mampu mencegah infeksi, antiinflamasi, dan membantu regenerasi sel baru. Tujuan penelitian ini adalah untuk mengetahui pengaruh bentuk sediaan topikal ekstrak gonad landak laut 4% memberikan efek penyembuhan luka bakar yang baik berdasarkan penyembuhan luka hingga 100%. Bahan yang digunakan dalam penelitian ini yaitu sediaan salep, krim dan gel yang mengandung ekstrak gonad bulu babi 4%, etil klorida, alkohol. Penelitian ini menggunakan metode eksperimental yang terdiri dari 8 kelompok perlakuan yaitu, 3 kelompok perlakuan sediaan salep, krim dan gel, 3 kelompok sediaan tanpa ekstrak (placebo) dan 2 kelompok kontrol. Masing-masing kelompok dilakukan 3 kali pengulangan (replikasi perlakuan). Hasil uji statistik Kolmogorov-Smirnov diperoleh nilai p>0.05 (0.2) yang berarti data terdistribusi normal. Hasil pengujian ANOVA p<0.05 (0.000) menunjukkan semua perlakuan memberikan efek yang berbeda signifikan. Berdasarkan uji BNT, menunjukan ekstrak gonad landak laut 4% yang dibuat dalam bentuk sediaan salep dan gel lebih baik dalam menyembuhkan luka bakar dibanding dengan sediaan krim. Hasil uji deskriptif, sediaan salep dan gel memberikan efek yang lebih cepat dalam penyembuhan luka bakar yaitu 27 hari, sedangkan sediaan krim 30 hari. Berdasarkan hasil tersebut, ketiga sediaan salep, gel dan krim dapat menyembuhkan luka bakar hingga 100% selama 27-30 hari, namun bentuk sediaan gel lebih baik memberikan efek luka bakar. Dari hasil penelitian, disarankan pada penelitian selanjutnya, untuk melakukan standarisasi bahan baku (zat aktif) dengan harapan efek yang diberikan lebih efektif.
Sumber Koping Pada Ibu yang Mengalami Baby Blues Syndrome di RS. Elim Rantepao
Authors: Tulak Lulu Alang , Yusriani Yusriani , Idris Fairus prihatin
Published: December 2023

Baby blues syndrome tergolong gangguan psikologis ringan yang kadang dialami oleh ibu postpartum. Untuk mengatasi baby blues syndrome, ibu dapat mengadopsi mekanisme koping. Penelitian ini bertujuan untuk mengetahui mekanisme koping pada ibu yang mengalami baby blues syndrome di Rumah Sakit Elim Rantepao. Jenis penelitian ini adalah penelitian kualitatif dengan pendekatan deskriptif. Partisipan terdiri dari 5 informan utama yaitu ibu yang mengalami baby blues syndrome, 3 partisipan pendukung (keluarga), dan 1 partisipan kunci (bidan yang merawat). Hasil penelitian yang didapatkan menunjukkan bahwa cara ibu menanggulangi stress amat bergantung pada sumber yang tersedia, seperti dukungan keluarga yang dijadikan ibu sebagai sumber koping yang terbesar, selain itu keyakinan spiritual, dukungan sosial, keseimbangan energy dan materi, juga dijadikan Ibu sebagai sumber kopingnya. Namun ada hal yang berbeda yang didapatkan, yaitu adanya belief atau kepercayaan dimana ibu melakukan ritual atau mempercayai mitos untuk mendapatkan ketenangan. Seperti mempercayai bahwa meminum air yang didoakan akan memberikan ketenangan pada Ibu, ada juga yang dimandikan sambil didoakan yang dipercaya dapat membuang aura-aura buruk serta memberikan ketenangan pada Ibu, kemudian ada juga kepercayaan yang dilakukan dengan cara meletakkan tumbuhan putri malu di bawah bantal anak agar anak tidak merepotkan ibu, dan ibu bisa lebih tenang beristirahat. Untuk itu dalam menghadapi baby blues syndrome, sangat diperlukan dukungan dari sumber koping agar kondisi ibu tidak berlanjut pada gangguan yang lebih berat.