bluuebunny/crossref_metadata_2025 huggingface dataset:
Efektivitas Technology-Enhanced Learning dalam Pembelajaran Interaktif Berbasis Kurikulum Merdeka di Kelas 5 SDN 01 Sukorejo Kab. Nganjuk
Authors: Jannah Latifatul , Nuriana Ervin
Published: February 2024

Peserta didik yang kurang aktif dalam pembelajaran di kelas dapat disebabkan beberapa faktor diantaranya yaitu faktor dari pendidik, media ajar yang digunakan ataupun materi yang dibawakan oleh pendidik. Oleh karenanya maka seorang pendidik perlu mengembangkan atau mencari cara agar pembelajaran lebih menghidupkan interaksi dari peserta didik. Hal yang dapat dilakukan yakni merancang fasilitas pembelajaran yang tepat agar peserta didik mendapatkan rangsangan untuk lebih tertarik untuk terlibah dalam pembelajaran sehingga akan memahami materi yang disampaikan oleh pendidik. Penguasaan teknologi juga merupakan hal yang penting dalam proses pembelajaran saat ini. Teknologi dapat dijadikan sebuah media pembelajaran yang menyenangkan untuk menarik minat peserta didik, karena media pembelajaran yang kurang menarik minat sulit untuk digunakan dalam memberikan pengalaman yang konkret kepada peserta didik. Penelitian yang dilakukan bertujuan untuk menganalisis dan mendeskripsikan efektivitas Technology-Enhanced Learning dalam pembelajaran interaktif berbasis kurikulum merdeka sesuai dengan kurikulum yang digunakan di sekolah tempat penelitian ini dilakukan. Penelitian ini menggunakan metode kualitatif dengan pendekatan deskriptif dari data- data yang sudah ditemui. Hasil dari pengumpulan data dan analisis temuan data didapatkan hasil bahwa efektivitas penggunaan Technology-Enhanced Learning dalam pembelajaran interaktif berbasis kurikulum merdeka pada siswa kelas 5 di SDN 01 Sukorejo Kab. Nganjuk terbukti sangat efektif dalam menghidupkan kelas, menunjang kondisi kelas yang menarik dan interaktif.
Pengembangan media monopoli cerpen untuk menganalisis unsur pembangun cerita pendek SMA Kelas XI
Authors: Magvira Ninin Choridatul , Utami Sri , Hermawan Agus
Published: February 2024

Abstrak: Tujuan dari penelitian ini adalah menghasilkan sebuah produk media pembelajaran. Media pembelajaran merupakan alat bantu yang digunakan dalam proses pembelajaran dengan tujuan merangsang pikiran peserta didik untuk mempermudah dalam penyampaian materi. Dalam penelitian ini, media yang dikembangkan berupa media Monopoli Cerpen yang terinspirasi dari permainan monopoli. Penelitian ini menggunakan model penelitian 4D yang dikembangkan oleh Thiagarajan dengan tahapan (1) pendefinisian, (2) perancangan, (3) pengembangan, dan (4) penyebaran. Teknik yang digunakan untuk pengumpulan data yaitu (1) observasi, (2) wawancara, dan (3) lembar angket. Uji validasi telah dilakukan oleh dua dosen, guru bahasa Indonesia, dan siswa SMA. Data yang diambil berupa data kuantitatif dan data kualitatif. Berdasarkan penelitian, hasil perolehan data kuantitatif dari ahli media sebesar 93%, ahli materi sebesar 98%, dari guru sebagai uji kepraktisan sebesar 96.50% dan dari siswa sebagai uji kemenarikan media sebesar 89%. Berdasarkan pemaparan dari aspek tersebut dapat disimpulkan bahwa media yang dikembangkan sangat layak dan dapat digunakan dalam proses pembelajaran.

Abstract: The purpose of this research is to produce a learning media product. Learning media is a tool used in the learning process with the aim of stimulating the minds of students to facilitate the delivery of material. In this study, the media developed was in the form of short story monopoly which was inspired by the monopoly game. This study uses a 4D research model developed by Thiagarajan with stages (1) definition, (2) design, (3) development, and (4) deployment. The techniques used for data collection are (1) observation, (2) interviews, and (3) questionnaires. The validation test has been carried out by two lecturers, an Indonesian language teacher, and a high school student. The data taken in the form of quantitative data and qualitative data. Based on the research, the results of obtaining quantitative data from media experts were 93%, material experts were 98%, from teachers as a practicality test of 96.50% and from students as a media attractiveness test of 89%. Based on the exposure of these aspects, it can be concluded that the media developed is very feasible and can be used in the learning process.
Nilai moral dalam cerita fantasi karya mahasiswa PGSD UNU Blitar: Kajian nilai pendidikan
Authors: Mu'alimah Isna Khuni , Nurmanita Tiara Sevi , Nisak Winda Khoirun , Niwangtika Widyarnes , Kurniasari Dwi
Published: February 2024

Abstrak:

Penelitian ini mengkaji cerita anak karya mahasiswa PGSD UNU Blitar yang bergenre fantasi dari segi nilai moral yang terkait dalam bidang pendidikan. Pendidikan merupakan wadah untuk melestarikan nilai-nilai moral salah satunya melalui cerita. Proses ini bertujuan untuk memberikan bekal kehidupan bagi siswa melalui proses pembudayaan dan pemberdayaan. Oleh karena itu sebagai seorang pendidik perlu memiliki kemampuan bersastra yang baik, salah satunnya adalah kemampuan menulis cerita. Metode penelitian menggunakan metode penelitian deskriptif kualitatif dimana data yang terkumpul berupa kata-kata. Data penelitian ini dikumpulkan menggunakan teknik baca, dan teknik catat. Sedangkan untuk teknik analisis data menggunakan teknik dialektik dan teknik analisis ini. Teknik dialektik digunakan dengan menghubungkan unsur-unsur yang ada dalam cerita fantasi karya mahasiswa dan mengintegrasikannya ke dalam satu kesatuan makna. Proses selanjutnya yakni membuat inferensi-inferensi yang dapat ditiru dan data sahih dengan memperhatikan konteks melalui analisis isi. Penelitian ini akan menghasilkan kajian mendalam nilai-nilai moral yang terkandung dalam cerita-cerita hasil karya mahasiswa.

 

Abstract:  This research examines children's stories written by PGSD UNU Blitar students in the fantasy genre in terms of moral values ​​related to the field of education. Education is a forum for preserving moral values, one of which is through stories. This process aims to provide provisions for life for students through acculturation and empowerment processes. Therefore, as an educator, you need to have good literary skills, one of which is the ability to write stories. The research method uses a qualitative descriptive research method where the data collected is in the form of words. This research data was collected using reading techniques and note-taking techniques. Meanwhile, the data analysis technique uses dialectical techniques and this analysis technique. The dialectical technique is used by connecting the elements in the student's fantasy story and integrating them into a single meaning. The next process is to make replicable inferences and valid data by paying attention to context through content analysis. This research will produce an in-depth study of the moral values ​​contained in the stories created by students.
Din Kültürü ve Ahlak Bilgisi Öğretmen Adaylarının Akademik Öz-Yeterlik ve Üstbilişsel Farkındalıklarının İncelenmesi
Authors: Osmanoğlu Cemil , Ulu Mustafa
Published: February 2024

Bu araştırmanın temel amacı Din Kültürü ve Ahlak Bilgisi (DKAB) öğretmen adaylarının akademik öz-yeterlikleri ile üstbilişsel farkındalıkları arasındaki ilişkiyi incelemektir. İlişkisel tarama modeliyle yürütülen araştırmanın örneklemini dokuz farklı üniversitenin İlahiyat ya da İslami İlimler Fakültelerinde 2022-2023 yıllarında öğrenim görmekte olan öğrenciler arasından basit tesadüfi örneklem yoluyla seçilen 744 öğrenci oluşturmaktadır. Veri toplama aracı olarak Owen & Froman (1988) tarafından geliştirilen ve Ekici (2012) tarafından Türkçeye uyarlanan Akademik Öz-yeterlik Ölçeği ve Durdukoca & Arıbaş (2019) tarafından geliştirilen Üstbilişsel Farkındalık Ölçeği ile kişisel bilgi formu kullanılmıştır. Araştırma sonucunda katılımcıların Akademik Öz-yeterlik Ölçeği ortalamasının 2,82; Üstbilişsel Farkındalık Ölçeği ortalamasının ise 3,46 olduğu görülmüştür. Akademik Öz-yeterlik Ölçeği genel puanında erkeklerin ortalaması kadınların ortalamasından daha yüksek olduğu, buna karşın Üstbilişsel Farkındalık Ölçeği genel ortalamaları arasında cinsiyet bazında anlamlı bir farklılaşma olmadığı bulgulanmamıştır. Akademik öz-yeterlik ölçeği ile Üstbilişsel farkındalık ölçeği genel puanları arasında orta düzeyli pozitif bir ilişki olduğu belirlenmiştir. Yine her iki ölçeğin alt boyutları arasında da belirgin anlamlı ilişkiler tespit edilmiştir. Üstbilişsel farkındalığın akademik öz-yeterliği yordama gücünü belirmek amacıyla yapılan Regresyon analizi sonucuna göre Üstbilişsel farkındalıklar hem genel düzeyde hem de Kişisel farkındalık, Organizasyonel farkındalık ve Yargısal farkındalık faktörleri bağlamında akademik öz-yeterliği istatistiksel olarak anlamlı bir şekilde yordamaktadır.
Differentially Private Guarantees for Analytics and Machine Learning on Graphs: A Survey of Results
Authors: Mueller Tamara T. , Usynin Dmitrii , Paetzold Johannes C. , Braren Rickmer , Rueckert Daniel , Kaissis Georgios
Published: February 2024

We study the applications of differential privacy (DP) in the context of graph-structured data and discuss the formulations of DP applicable to the publication of graphs and their associated statistics as well as machine learning on graph-based data, including graph neural networks (GNNs). Interpreting DP guarantees in the context of graph-structured data can be challenging, as individual data points are interconnected (often non-linearly or sparsely). This connectivity complicates the computation of individual privacy loss in differentially private learning. The problem is exacerbated by an absence of a single, well-established formulation of DP in graph settings. This issue extends to the domain of GNNs, rendering private machine learning on graph-structured data a challenging task. A lack of prior systematisation work motivated us to study graph-based learning from a privacy perspective. In this work, we systematise different formulations of DP on graphs, discuss challenges and promising applications, including the GNN domain. We compare and separate works into graph analytics tasks and graph learning tasks with GNNs. We conclude our work with a discussion of open questions and potential directions for further research in this area.
Numerical Composition of Differential Privacy
Authors: Gopi Sivakanth , Lee Yin Tat , Wutschitz Lukas
Published: February 2024

We give a fast algorithm to optimally compose privacy guarantees of differentially private (DP) algorithms to arbitrary accuracy. Our method is based on the notion of \emph{privacy loss random variables} to quantify the privacy loss of DP algorithms.The running time and memory needed for our algorithm to approximate the privacy curve of a DP algorithm composed with itself $k$ times is $\tilde{O}(\sqrt{k})$. This improves over the best prior method by Koskela et al. (2021) which requires $\tilde{\Omega}(k^{1.5})$ running time. We demonstrate the utility of our algorithm by accurately computing the privacy loss of DP-SGD algorithm of Abadi et al. (2016) and showing that our algorithm speeds up the privacy computations by a few orders of magnitude compared to prior work, while maintaining similar accuracy.
8-Bit Affordances: Jun Chikuma’s Soundtrack toFaxanadu
Authors: Cook Karen M.
Published: February 2024

In the heyday of Nintendo’s 8-bit era in the 1980s, the limitations and affordances of the console’s audio capabilities led composers and programmers to new heights of creativity. Jun Chikuma (竹間 淳 or 竹間 ジュン) was one such composer who developed new compositional strategies, techniques, languages, and styles for this new medium. Her work often appears on “hidden gems of video game music” lists, but it has yet to be discussed in scholarly literature. Nor hasFaxanadu(1987), itself considered by many an underrated classic. For this game, Chikuma created an unusually lengthy score comprising numerous distinct tracks, remarkably structured in modified arch form. Expanding on KC Collins’s (".fn_cite_year($collins_2007).
Out of the Blue
Authors: Ovenden Philippa
Published: February 2024

The Old Hall Manuscript (OH, c. 1413–1419) is the largest and most complete surviving witness to English music of the early fifteenth century. The extraordinary notational complexity encountered in OH has led to doubt being cast on the performability of some of the repertory copied within this manuscript (Bent 1969, 172). Adopting an approach that places historical theory (Dygon 2006)
Bearing capacity and the settlement of foundation on biomodified coastal soil
Authors: Shamshad Alam  , Anhar Yousuf Wani
Published: February 2024

Construction of the foundation on the marine the soil deposit is susceptible to excessive settlement and the construction of foundation is difficult. Although, the most common practice is to construct the raft foundation in these regions even for the low-rise building, excessive settlement can be observed in several building. So, in the present study, laboratory investigations have been done on the marine soil by modifying it with two different type of biopolymer such as Guar gum and Xanthan gum. The geotechnical properties of the soil modified with 1% and 1.5% biopolymer has been evaluated and the obtained properties has been used for settlement analysis. During the settlement analysis, the foundation soil model has been created as layered soil because the top layer has been replaced by biomodified soil. Several combi-nations have been created by varying the thickness of modified soil layer and the type and percentage of modifying agent. The settlement analysis has been performed in the settle 3D software and the biopolymer modification of soil has been found effective in controlling the foundation settlement.
A novel Colorcult hemoculture in early diagnosis of blood stream infection: A boon in meagre resources
Authors: Cinthujah Balachander  , Priya Sundararajan  , Vasanth Selvaraj Kailaiselvi  , Poongodi Santhana kumarasamy
Published: February 2024

Blood stream infections (BSIs) account for major cause of morbidity and mortality. Conventional hemoculture methods are time consuming, with poor sensitivity and high risk of contamination. Automated blood culture systems are highly sensitive but are overpriced. Hence, it is not suitable for resource poor settings. In this background, this study was done to analyze the sensitivity of novel non automated chemical sensor-based blood culture and to compare the time to detection of both conventional and colorimetric method of blood culture. Blood specimens were collected from 50 study participants, admitted with suspected sepsis, inoculated into the colorcult & conventional culture media and processed as per CLSI guidelines. Culture positive by both conventional and colorcult method was six (12%). Most of the study isolates were Gram negative bacteria (83.4%). The isolates were detected at the earliest within 96 hours by colorcult, whereas by conventional method only three (50 %) were detected within 96 hours and another three (50%) after seven days only. Owing to the escalation in BSIs associated morbidity and mortality, early diagnosis by a simple, cost effective, highly sensitive and specific method is an absolute necessity in resource poor settings. The performance of colorcult is superior to conventional method but cost effective than automated methods and can be used as an alternative method in the diagnosis of BSIs.
Pembacaan Semiotika pada Antologi Puisi Bulan yang Melayari Aksara Karya Ika Permata Hati Melalui Perspektif Riffaterre
Authors: Abror Muchlas , Pramesthi Sekar Arum Ayuning
Published: February 2024

Penelitian ini dilatarbelakangi adanya kesulitan dalam pemaknaan lambang-lambang pada puisi karena menyebabkan ketidaklangsungan ekspresi. Tujuan penelitian ini, untuk menemukan matriks, model, varian, dan hipogram pada puisi. Untuk sampai pada tujuan tersebut, peneliti menggunakan objek material tiga puisi yang berjudul Pulang, Haruku, dan Secangkir Kopi yang ada pada antologi Bulan Yang Melayari Aksara karya Ika Permata Hati. Sementara semiotika Riffaterre digunakan sebagai objek formal dengan alasan semiotika menjadikan lambang sebagai objek kajiannya. Dalam pengumpulan data digunakan metode baca, simak, diserta dengan teknik catat dan metode hermeneutika digunakan untuk menganalisis matriks, model, varian, dan hipogram pada ketiga puisi tersebut.  Hasil penelitian dari ketiga puisi tersebut ditemukan matriks yaitu tentang kerinduan, varian di ketiganya tentang kenangan yang menyakitkan, sementara cinta yang tidak berujung bahagia, kegagalan menghapus cinta yang menyakitkan, tempat baru yang tidak membebaskan menjadi varian dari ketiga puisi tersebut dan Pulau Bali menjadi hipogram dari ketiganya.
Evaluation of a Novel Battery-Operated Tumbler Device for Use in the Detection of Mouse Pathogens for Rodent Health Monitoring
Authors: Sidhu Harmaneek K , Perkins Cheryl L , Henderson Ken S , Hibl Brianne M , Nouer Simonne S , Tolley Elizabeth A , Hamilton David J
Published: February 2024

The search for alternatives to live animal sentinels in rodent health monitoring programs is fundamental to the 3Rs (Reduction, Replacement, and Refinement) of animal research. We evaluated the efficacy of a novel battery-operated tumbler device that rotates soiled bedding in direct contact with sample media against the use of exhaust sample media and soiled bedding sentinel (SBS) mice. Four rodent racks were used, each with 3 test cages: a cage with a tumbler device that rotated for 10 min twice a week (TUM10), a cage with a tumbler device that rotated for 60 min twice a week (TUM60), and a cage housing 2 female Crl:CD1(ICR) mice. Every 2 wk, each test cage received soiled bedding collected from all cages on each respective rack. In addition to soiled bedding, the tumbler device contained various sample collection media: a contact Reemay filter (3 mo-cRF) that remained in the tumbler for the duration of the study, a contact Reemay filter (1 mo-cRF) that was replaced monthly, adhesive swabs (AS) that were added at every biweekly cage change, and an exhaust Reemay filter located at the exhaust outlet of the cage. All analyses were performed by direct PCR for both sample media in the animal-free methods, and fecal pellet, body swab, and oral swabs were collected from sentinel mice. Out of 16 total pathogens detected, assessment of 1 mo-cRF from both TUM10 and TUM60 cages detected 84% and 79% of pathogens, respectively, while SBS samples detected only 47% of pathogens. AS in TUM60 and TUM10 cages detected the fewest pathogens (24% and 13%, respectively). These results indicate that the novel tumbler device is an effective and reliable tool for rodent health monitoring programs and a suitable replacement for live animal sentinels. In this study, 1 mo-cRF in TUM10 cages detected the highest number of pathogens.
Frascos de cristal, plátanos y moscas: género, emociones y prácticas de la genética de Drosophila
Authors: Velasco Martín Marta
Published: February 2024

Los plátanos y los tarros de cristal fueron y son componentes de la cultura material de la genética de Drosophila, como lo fueron y son también las moscas que crecían en su interior. Estos objetos son objetos híbridos —materiales, sensoriales y emocionales—, que circularon entre el campo y el laboratorio, entre las aulas, puestos de investigación y cocinas de las casas de quienes se dedicaron a los estudios de la herencia y la evolución. Circularon también a través del tiempo y del espacio geográfico al formar parte del conocimiento colectivo de la comunidad de genetistas de Drosophila, de sus recuerdos y de los de sus hijas e hijos. A través de la combinación de fuentes escritas, académicas e institucionales y de otras que son orales, subjetivas y emocionales, cobran vida y con ellos las actividades y prácticas de quienes los utilizaban, casi siempre mujeres. Al evocarlos, aparecen también normas como las de género, que rodeaban a las personas en el momento de la experiencia y juicios de valor que elaboraron, y se elaboraron, sobre los objetos, sus usos y las identidades de quienes los emplearon. Este artículo pretende así, estudiando prácticas y objetos de una disciplina como la genética de Drosophila, contribuir a la construcción de una historia de la genética más inclusiva, a la historia de las mujeres científicas y a los estudios sobre el papel de las emociones, el cuerpo y la memoria en la construcción de conocimiento histórico y científico.
Transforming wild rabbits’ overpopulation problem into a local biotic resource of Lemnos island
Authors: Gialeli Maria , Vasios Georgios , Zaragkali Flora , Roumelioti Aikaterini , Tsiota Georgia , Koufos Georgios , Tapazidou Polyxeni , Kakaroglou Ioannis , Antoniadis Ioannis , Troumbis Andreas
Published: February 2024

For more than 20 years, the European Wild Rabbit (WR) (Oryctolagus Cuniculus) is considered a pest in Lemnos island, Greece, due to significant crop damage. Authorities took insufficient actions to control WR overpopulation, resulting only in managing its effect on crop losses with farmers’ compensation. The current study aims to redefine the WR problem in Lemnos by transforming the WR population to a local commodity, where hunting could supply the local market (restaurants and butcheries) with WR products. Semi-structured qualitative interviews from local stakeholders were analyzed using content analysis, to identify their priorities on the WR problem. Additionally, relative local press articles (2016–2021) were recorded and analyzed qualitatively. Furthermore, European and National legal framework was studied to understand the implementation of hunting and selling procedures of WR in local markets. The main events’ timeline of the WR overpopulation problem was identified and the stakeholders’ key points were combined to create a viable solution. These highlights include the affected areas of interest, hunting processes, and local interest in the supply and demand of WR consumption. The national legislation on hunting and selling of WR at the local market was identified, and its activation is proposed for turning the WR into a sustainable product of local gastronomy.
The present research and the APC were funded by EPAnEk-NRSF 2014-2020; Operational Program “Competitiveness, Entrepreneurship and Innovation, Call 111 “Support of Regional Excellence” in the context of the implementation of the program: AGRICA II: AGrifood Research and Innovation Network of ExCellence of the Aegean, which is co-financed by the European Regional Development Fund (ERDF), MIS code: 5046750.
Sensitive method for the simultaneous detection of ten azole contaminants in water samples by SPE-LC-MS/MS
Authors: Tenea Anda , Iancu Vasile , Chiriac Florentina , Pirvu Florinela , Serban Gabriel , Cojocaru Victor , Vasile Gabriela
Published: February 2024

A new analytical method was developed for the determination of azole contaminants from environmental samples (surface water, drinking water, wastewater) by solid phase extraction (SPE) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) quantification. The separation of the compounds was achieved using a Zorbax Eclipse XDB C18 chromatographic column (2.1 x 100 mm, 3.5 μm). The quantification limits varied in the range of 3.6 ng/L (ipconazole) to 8.4 ng/L (climbazole), for wastewater samples, 1.44 ng/L ÷ 3.36 ng/L for surface water samples, and 0.72 ng/L and 1.68 ng /L in drinking water, respectively. The values of the recovery percentage and the precision data obtained after applying the extraction procedure for all compounds indicated values in accordance with LC methods.
INDICADORES NA ASSISTÊNCIA CIRÚRGICA DE UM HOSPITAL UNIVERSITÁRIO
Authors: Chourabi Lizandra Flores , Souza Vinícius Rodrigues de , Silva Luciana  Gomes da , Costa Sarah Menezes , Balonecker Alexmália Fiorini da Costa , Da Silva Figueira Silvia Helena , Pereira Matias Evany , Lopes Lima Dayse Kelly
Published: February 2024

Introdução: Os indicadores são, ferramentas essenciais em diversas áreas, incluindo a saúde e a gestão de serviços de atendimento A utilização de indicadores no centro cirúrgico é primordial, por ser considerada um setor extremamente complexo que abrange o trabalho de equipes multiprofissionais que necessitam estar em sintonia em relação aos inúmeros processos e sub processos que são exigidos na produção de cirurgias. Objetivo: Compreender as percepções dos gestores acerca da utilização de indicadores na assistência cirúrgica em um hospital universitário. Métodos: Estudo descritivo e exploratório, de abordagem qualitativa, realizado com 05 gestores do centro cirúrgico de um hospital universitário. Os dados coletados no período de agosto e setembro de 2023, por meio de entrevistas individuais semiestruturadas foram analisados e submetidos à análise temática de Minayo. Resultados: Dos resultados emergiram três categorias: percepção de gestores sobre o uso de indicadores para avaliação do processo cirúrgico; a fragilidade da educação permanente no uso dos indicadores e a suspensão de cirurgias como indicador de qualidade da assistência cirúrgica. Conclusão: A análise demonstra a importância dos sistemas de indicadores no centro cirúrgico e sua relação direta com o cuidado do paciente, a necessidade de capacitação para a utilização dos indicadores e a falta de sua implementação relacionada com a suspensão de cirurgias, acarretada pela falta de gerenciamento de recursos materiais.
Narrative Self-Transcendence: Decreased Regret and Increased Acceptance Over Late Midlife
Authors: Reischer Hollen N. , Couch Nathan , Wright Mya N. , Duarte Andrew J. , McAdams Dan P.
Published: February 2024

Introduction: Self-transcendence—connectedness within and beyond the self—is a complex phenomenon theorized to increase with age, but evidence is mixed. This longitudinal study is the first to investigate changes in self-transcendence across late midlife using life story narratives. Method: We tracked self-reported and narrative identity self-transcendence scores of 163 participants as they aged from M=56.4 (SD=0.95) to M=64.5 (SD=0.94). Participants were 64.4% women, 35.6% men; 55.2% White, 42.9% Black, 1.8% interracial/other; median income was $75,000–$100,000; median education was college graduate. Results: Self-transcendence narrative themes of closure and self-actualization increased significantly over time, especially between ages 60–65, but self-reported self-transcendence did not change. These trends were not uniform; race by gender groups exhibited distinct trajectories over time.Discussion: Late midlife is seen as ushering in opportunities for increased self-transcendence, especially acceptance of oneself and one’s life. We found some of the strongest empirical evidence of this phenomenon to date. On average, U.S. Black and White adults narrated their life stories with less regret and more satisfaction with self across late midlife. Findings demonstrate the utility of leveraging first-person narrative identity methods to collect and analyze data about rich, complex personality constructs and highlight positive changes associated with late midlife.
How Do People Perceive Immigrants? Relating Perceptions to Numbers
Authors: Sidler Petra , Knotz Carlo Michael , Ruedin Didier
Published: February 2024

How does the general public perceive immigrants, whom do they think of when thinking about ‘immigrants’, and to what extent are these perceptions related to the actual composition of immigrant populations? We use three representative online surveys in the United States, South Africa, and Switzerland (total N=2,778) to extend existing work on the perception of immigrants in terms of geographic coverage and individual characteristics. We also relate these responses to official statistics on immigration and integration patterns. In all three countries, there are significant discrepancies between perceptions of immigrants and their real proportion in the population and characteristics. Although we observe clear country differences, there is a striking pattern of people associating ‘immigrants’ with ‘asylum seekers’ in all three countries. We consider two possible explanations for the differences between perceptions and facts: the representativeness heuristic and the affect heuristic. In contrast to previous research, we find only partial support for the representativeness heuristic, whereas the results are consistent with the affect heuristic. We conclude that images of ‘immigrants’ are largely shaped by pre-existing attitudes.
Neue Reaktortechnologien, strategische Deglobalisierung und "Tech Wars": Kontraproduktive Folgen für das nukleare Nonproliferations- und Verifikationsregime?
Authors: Rotte Ralph
Published: February 2024

Given the variously stated „renaissance of nuclear power“, including a number of potential newcomers to the civilian use of nuclear energy, this paper addresses implications of a propagation of nuclear facilities and new reactor technologies for the nuclear nonproliferation and verification regimes. A special focus is on small modular reactors (SMRs) which, despite technological and economic doubts, are currently under development in various countries. Quantitative and qualitative problems in international verification of SMRs are enhanced by the political framework of international great power competition, especially among the U.S., China and Russia with their respective allies, the subsequent global technological and economic conflicts, and the structural, mainly financial weaknesses of the IAEA. This leads to the nuclear technological and energy economic dynamics resulting in potentially serious risks for the stability of the nuclear nonproliferation regime.
Who is on Twitter (“X”)? Identifying demographic of Twitter users
Authors: Mosleh Mohsen , Rand David Gertler
Published: February 2024

Twitter (currently known as “X”) has become a prominent platform for public discourse and opinion sharing. However, it is unclear how representative Twitter users are of the broader U.S. population. Here, we analyze a unique large dataset of roughly 300 million minimally politically active Twitter users to infer demographic characteristics including gender, age, political affiliation, and location. We compared these inferred demographics to the U.S. census data. Results indicate that Twitter users are disproportionately younger, more Democratic, and more male compared to the general population. Additionally, Twitter users overrepresent individuals from the South and West census regions. Our results have important implications for researchers, marketers, policymakers and others seeking to understand trends and activity on Twitter, and how they relate to the general US population.
Communicative activity in teaching professionally oriented English: a methodological aspect
Authors: Sagiyeva A.T.
Published: February 2024

New conditions determine new requirements to the quality of specialists’ training for professional activity. It is necessary to emphasize the important role of communicative activity development in professional-personal direction. The purpose of this article ― to systematize the results obtained in the framework of pedagogical research conducted on the basis of Aktobe Regional University named after K. Zhubanov, with the 3 rd year students of the specialty “5B010200 ― “Pedagogy and Methods of Primary Education”” with the Kazakh language of training. Scientific importance is designated by means of allocation of theoretical and conceptual device, practical importance consists in the chosen and tested complex of diagnostics, and techniques on communicative activity. The methodology of research is based on activity (A. N. Leontiev, V. A. Slastenin, etc.) and acmeological (N. V. Kuzmina, etc.) approaches, review-analytical and diagnostic research methods. The main results of the study were the systematization of the identified components of communicative activity, methods and techniques for teaching foreign language to students of non-linguistic specialties. The value is the cultural enrichment of the student on the basis of competently selected teaching material. The practical value of the results of the work is based on methodological recommendations to university faculty working in this area.
MVDet: Encrypted malware traffic detection via multi-view analysis
Authors: Cui Susu , Han Xueying , Dong Cong , Li Yun , Liu Song , Lu Zhigang , Liu Yuling
Published: February 2024

Detecting encrypted malware traffic promptly to halt the further propagation of an attack is critical. Currently, machine learning becomes a key technique for extracting encrypted malware traffic patterns. However, due to the dynamic nature of network environments and the frequent updates of malware, current methods face the challenges of detecting unknown malware traffic in open-world environment. To address the issue, we introduce MVDet, a novel method that employs machine learning to mine the behavioral features of malware traffic based on multi-view analysis. Unlike traditional methods, MVDet innovatively characterizes the behavioral features of malware traffic at 4-tuple flows from four views: statistical view, DNS view, TLS view, and business view, which is a more stable feature representation capable of handling complex network environments and malware updates. Additionally, we achieve a short-time behavioral features construction, significantly reducing the time cost for feature extraction and malware detection. As a result, we can detect malware behavior at an early stage promptly. Our evaluation demonstrates that MVDet can detect a wide variety of known malware traffic and exhibits efficient and robust detection in both open-world and unknown malware scenarios. MVDet outperforms state-of-the-art methods in closed-world known malware detection, open-world known malware detection, and open-world unknown malware detection.
Relevance of tumor markers for prognosis and predicting therapy response in non-small cell lung cancer patients: A CEPAC-TDM biomarker substudy
Authors: Geiger Kimberly , Joerger Markus , Roessler Max , Hettwer Karina , Ritter Christoph , Simon Kirsten , Uhlig Steffen , Holdenrieder Stefan
Published: February 2024

BACKGROUND:

Protein tumor markers are released in high amounts into the blood in advanced non-small cell lung cancer (NSCLC).

OBJECTIVE:

To investigate the relevance of serum tumor markers (STM) for prognosis, prediction and monitoring of therapy response in NSCLC patients receiving chemotherapy.

METHODS:

In a biomarker substudy of a prospective, multicentric clinical trial (CEPAC-TDM) on 261 advanced NSCLC patients, CYFRA 21-1, CEA, SCC, NSE, ProGRP, CA125, CA15-3 and HE4 were assessed in serial serum samples and correlated with radiological response after two cycles of chemotherapy and overall (OS) and progression-free survival (PFS).

RESULTS:

While pretherapeutic STM levels at staging did not discriminate between progressive and non-progressive patients, CYFRA 21-1, CA125, NSE and SCC at time of staging did, and yielded AUCs of 0.75, 0.70, 0.69 and 0.67 in ROC curves, respectively. High pretherapeutic CA15-3 and CA125 as well as high CYFRA 21-1, SCC, CA125 and CA15-3 levels at staging were prognostic for shorter PFS and OS –also when clinical variables were added to the models.

CONCLUSIONS:

STM at the time of first radiological staging and pretherapeutic CA15-3, CA125 are predictive for first-line treatment response and highly prognostic in patients with advanced NSCLC.
La primer gran crisis de semiconductores del siglo XXI
Authors: Martínez Gómez Clara Iliana , Sánchez Gaspariano Luis Abraham
Published: February 2024

La actual crisis de semiconductores no es un fenómeno nuevo, han existido ya otras crisis en el pasado;sin embargo, la que se encuentra en curso tiene elementos inusitados que la hacen única ensu tipo y de gran complejidad. Existe la idea generalizada que el principal factor que derivó en estasituación crítica ha sido la pandemia de la Covid-19, no obstante, este es sólo uno de otros tantos quese han concatenado para exacerbar este fenómeno, cuyas repercusiones económicas han puesto demanifiesto la dependencia de la sociedad actual hacia la tecnología.
MINI FÁBRICAS: LAS LEVADURAS Y SU IMPORTANCIA EN LAS FERMENTACIONES INDUSTRIALES
Authors: Mendoza García Etzael  Alexis , Barrientos Gamez Elda Dilena Barrientos Gamez
Published: February 2024

En el presente trabajo se muestra un panorama acerca de las levaduras, desde como antiguamente fueron descubiertas gracias a un momento azaroso y como en la actualidad se han convertido en especies de interés en el ámbito biotecnológico, siendo utilizadas en amplios procesos industriales, desde la fabricación de alimentos y bebidas, hasta como su uso se ha innovado hasta ser utilizadas en la formación de biodiesel, biorremediación y el ámbito farmacéutico.
UNA VISTA DE SOSLAYO A LA Helicobacter pylori
Authors: Olivares Hernández Jesús Aldahir
Published: February 2024

La Helicobacter pylori (H. pylori) es una bacteria gram tipo flagelada, microaerofílica y espiralada, considerada la causa principal de gastritis crónica y atrófica, de úlcera péptica, así como de linfoma gástrico y carcinoma gástrico. Su importancia se debe a que causa infecciones en el aparato digestivo, a su vez mayoritariamente es responsable de daños a nivel de la mucosa gástrica ya que esta bacteria, al soportar el ph del ácido gástrico, genera una malformación adaptativa de la mucosa para su inserción y mortalidad de supervivencia de la misma, ocasionando diferentes atrofias y úlceras en la pared estomacal del ser humano en el proceso de adaptarse al entorno gástrico. Afecta a la población en general, sin importar género o edad, se cree que es adquirida durante la infancia y los síntomas se presentan más adelante. En 1982 fue descubierta por los científicos Warren y Marshall, encontrando que está bacteria daña la pared de la mucosa gastroduodenal, generando una infección que si no se es tratada a tiempo puede generar cambios irreversibles en la homeostasis del sistema digestivo. Es por ello, que una intervención oportuna en su diagnóstico con las diferentes técnicas y pruebas existententes para su detección, además de saber cómo se propaga (vías de transmisión), podría evitar cierto tipo de afecciones o patologías que acompañan a esta infección que son perjudiciales para el organismo, así mismo saber la importancia de que no es una bacteria que se debe tomar a la ligera y conlleva a un tratamiento con especiales fármacos.
Automoción eléctrica en México
Authors: Sánchez Gaspariano Luis Abraham , Martínez Gómez Clara Iliana
Published: February 2024

La movilidad urbana experimenta uno de los mayores cambios sociales, tecnológicos y económicos de una generación, motivado por tres fuerzas disruptivas: los vehículos eléctricos, los servicios de movilidad bajo demanda, y los vehículos conectados y autónomos. En este trabajo se discute la primera de esas tres fuerzas, la electrificación vehicular, enfocándonos en las perspectivas y retos que enfrenta la automoción eléctrica en México. Cabe señalar que al momento de la redacción de éste artículo, el gobierno del estado de Puebla presentó el plan para el despliegue de cargadores de vehículos eléctricos en dicha entidad federativa con la intención de posicionar a Puebla como un Hub de electromovilidad de referencia internacional. Por otro lado, al igual que en el caso de los vehículos autónomos, el marco jurídico sobre el cual se establezcan las regulaciones en materia de autos eléctricos debe ser adecuado para impulsar el uso de esta tecnología. Esta adecuación abarca tanto a las leyes establecidas en materia energética como las nuevas iniciativas de ley derivadas del uso de la automoción eléctrica, así como a las normas oficiales que atienden temas relacionados con electromovilidad y seguridad vehicular. Finalmente, la transición hacia la electromovilidad en nuestro país requiere la implementación de una política pública integral que contemple: el marco jurídico adecuado para impulsar y regular el uso de las nuevas tecnologías; apoyar a los potenciales consumidores de vehículos híbridos y eléctricos con incentivos fiscales y no fiscales; y promover el crecimiento de la red de estaciones de recarga.
Hormonas Esteroideas Sexuales: Moléculas Moderadoras de la Infección Bacteriana
Authors: Ramírez-Paz-y-Puente Gerardo A. , Vázquez-Cruz Candelario , Sánchez-Alonso Patricia , Negrete-Abascal Erasmo
Published: February 2024

El desarrollo de cualquier organismo es un evento jerárquico y secuencial que ocurre a través de la comunicación celular. Estos procesos de comunicación en eucariontes se llevan a cabo por medio de moléculas diversas, incluidas las hormonas. Las hormonas esteroideas participan en el desarrollo de los vertebrados, para controlar los rasgos distintivos de género, y que con ello pueda ocurrir la reproducción. Los andrógenos, estrógenos y progestágenos son fundamentales en el desarrollo del nuevo ser vivo, porque marcan a las diferentes células, de la madre gestante y del producto. Estas hormonas al ser mensajeros de flujos metabólicos son percibidas por los receptores celulares del vertebrado en desarrollo, aunque también pueden ser detectadas por algunos microorganismos circundantes que forman parte del microbioma. Así, estos microorganismos reconocen: i) el momento de desarrollo del hospedero, ii) el vigor o la debilidad del hospedador y iii) los sistemas de defensa contra las infecciones incluyendo la formación de biopelícula. La comunidad microbiana percibe la fortaleza del sistema inmune, por medio de la concentración de hormonas, y se mantiene contenida en las biopelículas o se dispersa a otros tejidos al detectar un sistema inmune débil, dañando al hospedero. Los cambios en la concentración de hormonas también provocan cambios en concentraciones de moléculas como glucosa y aminoácidos, que modifican el crecimiento microbiano, dificultando más el control de una infección. Comprender la importancia de las hormonas en la susceptibilidad a las infecciones es intrincado y desafiante; en este texto se muestra un panorama del tema.
VEJEZ Y REDES SOCIALES: EL AUGE DE LAS COMUNIDADES VIRTUALES
Authors: González Rodríguez Diana
Published: February 2024

El presente trabajo expone las implicaciones del uso de las Tecnologías de la Información y Comunicación (TIC) en la vejez, dado que estas herramientas son de gran importancia para promover la autonomía en la realización de diferentes actividades cotidianas. Sin embargo, se observa la tendencia a crear brechas en el acceso, aprendizaje y percepción de los medios digitales, a medida que las personas envejecen, atravesado por los estereotipos y las condiciones de rezago que viven las personas de 55 años en adelante en México (McCabe, Montes de Oca, Vivaldo-Martínez, Alhena, Arroyo, Aparicio, Avalos, Garay y Rivera, 2022). Todo ello, manifestado en medio de la pandemia por COVID-19, reflejando relaciones de desigualdad en la vejez, pero también maneras de conectar y solidarizar a través de las comunidades virtuales en Facebook u otras redes de comunicación en el espacio digital, interactuando desde los comentarios, hasta las reacciones, para acompañarse mutuamente. A modo de conclusiones, el impacto del confinamiento en las personas mayores dio lugar a ejercer el derecho a la información y el acceso a la tecnología, para garantizar una vida plena con la variedad de oportunidades que ofrece la virtualidad como las formas de convivencia híbrida, entre lo presencial y lo digital, haciendo consciencia de los peligros que implica este entorno.
¿QUÉ HAY DE NUEVO? TERAPIAS EMERGENTES PARA EL TRATAMIENTO DE DIABETES MELLITUS
Authors: D.L.S-Corone José Daniel , Belchez-Rodriguez Jorge Rodolfo , Calderon-Quiroz Diana
Published: February 2024

La diabetes mellitus tipo 2 es una enfermedad caracterizada por la resistencia a la insulina, su falta de generación, o ambas. Esta enfermedad afecta el metabolismo de quienes la padecen y pueden presentarse complicaciones si no es controlada.La etiología u origen de la enfermedad se atribuye al mal funcionamiento del control de glucemia en sangre por parte del páncreas, además de que se ha demostrado la relación entre algunos genes y el desarrollo potencial de diabetes.  Actualmente existen terapias que mejoran la calidad de vida, en México una de las más empleadas es la inyección de insulina. Otras alternativas incluyen la modificación de la dieta de los pacientes y el consumo de algunos fitocompuestos con propiedades terapéuticas. Las terapias emergentes descritas incluyen: el reemplazo de células beta pancreáticas, inhibidores del cotransportador SGLT2, células madre, y la terapia genética. Así mismo se describe la importancia de los conocimientos computacionales en la predicción de la diabetes mellitus tipo 2.
EFECTOS EN LA SALUD POR CONTAMINACIÓN DE METALES PESADOS EN LA COMIDA RÁPIDA
Authors: Espinoza de Luna Martin Salvador , Ramirez Sanchez Karen
Published: February 2024

Esta revisión bibliográfica tiene como objetivo dar a conocer el contenido de diferentes tiposde comida rápida y los efectos adversos en la salud por consumo excesivo de la misma, así comoevaluar diversas enfermedades provocadas por este consumo y los efectos provocados debidoa los altos niveles tóxicos contenidos en estos alimentos procesados. La investigación se realizópara dar a conocer el contenido de metales pesados en la comida rápida, ya que son alimentosque la población consume con mucha frecuencia y puede ser dañino para la salud, por lo quealertar sobre los efectos que tiene un consumo excesivo de esta comida es importante para laprevención de enfermedades. La metodología se basó en una revisión de artículos relacionadosal tema en el cual se recabo información para el desarrollo del presente trabajo. Se establecióuna búsqueda con los temas de interés y con relación al tema a desarrollar, ya que el tema esextenso, es decir, engloba el sector de producción hasta la comercialización de estos. Con estainvestigación podemos concluir que principalmente la comida rápida como lo son hamburguesas,hot dogs, pizza y alitas, son los alimentos que frecuentemente causan efectos nocivos parala salud humana, puesto que son los que tienen un contenido alto en metales pesados; por ello esrelevante sustituirlos por alimentos más saludables, con el mismo contenido proteico y valornutricional, como lo es una ensalada, atún, verduras hervidas y consumir productos que esténlibres de conservadores para evitar las posibles enfermedades.
VACUNAS CON VESÍCULAS DE MEMBRANA EXTERNA: ¿EL FUTURO DE LAS VACUNAS?
Authors: Díaz-Hernández Pablo
Published: February 2024

Prevenir la propagación de una enfermedad, sea por patógenos virales o bacterianos, implicabrindar protección a miles de millones de personas y los factores subsecuentes duranteel proceso. La vacunación, es sin duda, la manera más efectiva de lograr esto. Muchos paísespriorizan la realización de campañas de vacunación procurando el bienestar en salud públicade sus habitantes. El desarrollo de vacunas se ha situado en 6 tipos principales, cuya respuestaes efectiva para muchas enfermedades, sin embargo, algunas demostraron tener limitantespara determinadas condiciones clínicas. Por ello, la identificación de nuevos candidatos paradesarrollar vacunas ha captado la atención de muchos grupos de investigación. De acuerdo conla respuesta inmune humoral y celular inducida por una vacuna, es que se mide su efectividadcontra una enfermedad. Las Microvesículas (MVs) son vesículas de tamaño nanométrico quese secretan al espacio extracelular, cuyo contenido se conforma de carbohidratos, proteínas,lípidos, ácidos nucleicos (ADN y ARN) y otros metabolitos. Dicha conformación puede utilizarsecomo un vehículo que transporte para antígenos y moléculas inmunogénicas directamente a lascélulas diana. Ya se ha desarrollado una vacuna para la bacteria multirresistente Neisseria gonorrhoeaeutilizando vesículas de membrana externa (OMVs), cuya respuesta inmune fue prometedora.En esta revisión, se estudiará la participación de las microvesículas secretadas porbacterias Gram-positivas y Gram-negativas de distintos aislados, procesos de patogenicidad enlos que participan, utilidad en el transporte de moléculas inmunogénicas y su efectividad comocomponentes vacunales contra bacterias multirresistentes.