bluuebunny/crossref_metadata_2025 huggingface dataset:
Not Led by the Nose: Volatiles from Undamaged Eucalyptus Hosts Do Not Influence Psyllid Orientation
Authors: Farnier Kevin , Davies Noel W. , Steinbauer Martin J.
Published: November 2018

Psyllids (Hemiptera: Psylloidea) are small sucking insects with high host plant specificity. Despite the primitive olfactory system of psyllids, some species have been suggested to rely on host plant volatiles (HPVs) for seasonal migration between summer deciduous hosts and winter coniferous hosts. Similarly, enhanced attraction of psyllid vectors has been observed as a result of the manipulation of host odors by plant pathogens. As yet, there are no studies of olfaction in psyllids that utilize evergreen eucalypt hosts. We investigated the behavioral responses of adults of four Eucalyptus-feeding psyllids—Ctenarytaina eucalypti, C. bipartita, Anoeconeossa bundoorensis and Glycaspis brimblecombei—to their respective HPVs in Y-tube olfactometer bioassays. We also used existing physiological data for C. eucalypti to investigate potential olfactory tuning that may modulate the preference for morphologically juvenile leaves over morphologically adult leaves. Although adult C. eucalypti were consistently repelled by HPVs from damaged host leaves, none of the species exhibited positive chemotaxis to HPVs from undamaged leaves. Surprisingly, G. brimblecombei was repelled by HPVs from undamaged host leaves. Our findings provide little support for a significant role of olfaction in host location by Eucalyptus-feeding psyllids. We propose a number of ecological hypotheses to explain these unexpected findings.
Climatic Niche Model for Overwintering Monarch Butterflies in a Topographically Complex Region of California
Authors: Fisher Ashley , Saniee Kiana , Van der Heide Charis , Griffiths Jessica , Meade Daniel , Villablanca Francis
Published: November 2018

We use climatic conditions that are associated with known monarch butterfly overwintering groves in California to build a Maxent model, and focus on the fine scale probability of overwintering grove occurrence in a topographically complex region of the state (Santa Barbara County). Grove locations are known from recent and historical surveys and a long-term citizen science database. The climatic niche model performs well, predicting that overwintering habitat is most likely to occur along the coast and at low elevations, as shown by empirical data. We then use climatic variables in conjunction with climate change scenarios to model the future location of overwintering habitat, and find a substantial shift in the predicted distribution. Under a plausible scenario, the probability of occurrence of overwintering habitat directly reflects elevation, with coastal regions having a reduced probability relative to today, and higher elevation sites increasing in probability. Under a more extreme scenario, high probability sites are only located along ridgelines and in mountaintop regions of the county. This predicted shift in distribution is likely to have management implications, as sites that currently lack monarchs may become critical to conservation in the future. Our results suggest that estimating the size of the western overwintering population in the future will be problematic, unless annual counts compensate for a shift in the distribution and a potential change in the number and location of occupied sites.
Barriers and Facilitators in Implementing Non-Face-to-Face Chronic Care Management in an Elderly Population with Diabetes: A Qualitative Study of Physician and Health System Perspectives
Authors: Bazzano Alessandra , Wharton M. , Monnette Alisha , Nauman Elizabeth , Price-Haywood Eboni , Glover Cathy , Dominick Patricia , Malone Peggy , Hu Gang , Shi Lizheng
Published: November 2018

The burden of illness related to diabetes and its complications is exceedingly high and growing globally. Systematic approaches to managing chronic care are needed to address the complex nature of the disease, taking into account health system structures. This study presents data collected from interviews with physicians, health system administrators, and other healthcare staff about chronic care management for elderly people with diabetes co-morbid with other chronic conditions in light of new programs intended to reduce barriers by incentivizing care encounters that take place through telephone and electronic communications (non-face-to-face care). Results indicate that health system personnel view non-face-to-face care as potentially providing value for patients and addressing systemic needs, yet challenging to implement in practice. Barriers and facilitators to this approach for managing diabetes and chronic care management for its complications are presented, with consideration to different types of health systems, and recommendations are provided for implementation.
Hamstrings and Quadriceps Muscles Function in Subjects with Prior ACL Reconstruction Surgery
Authors: Faxon Jamie L. , Sanni Adeola A. , McCully Kevin K.
Published: November 2018

Background: As the knee joint is a common site for injury among younger people, the purpose of this study was to measure the skeletal muscle endurance and strength on people with prior anterior cruciate ligament (ACL) knee reconstruction surgery. Method: Young healthy female subjects who reported having knee reconstruction surgery more than one-year prior were tested. The skeletal muscle endurance index (EI) of the hamstrings and quadriceps muscles was determined as the decline in the specific muscle acceleration in response to 2 Hz, 4 Hz, and 6 Hz electrical stimulation. Maximal isometric muscle strength (MVC) was measured in the hamstrings and quadriceps muscles. Results: The hamstrings muscles in the injured leg had less endurance than the non-injured leg at 6 Hz stimulation (55.5 ± 13.2% versus 78.0 ± 13.3%, p < 0.01). Muscle endurance was not reduced in the quadriceps muscles in the injured leg compared to the non-injured leg at 6 Hz stimulation (78.0 ± 13.3% versus 80.3 ± 10.0%, p = 0.45). There were no differences in MVC between the injured and non-injured legs for either the hamstrings (p = 0.20) or quadriceps muscles (p = 0.67). Conclusions: Muscle endurance was reduced in the hamstrings muscles at least one-year post injury, while hamstrings strength was recovered. Reduced hamstrings muscle endurance could be a result of lack of endurance training during rehabilitation. This may contribute to re-injury in the muscle, even in people who have recovered muscle strength.
Effect of Welding Current on Weld Formation, Microstructure, and Mechanical Properties in Resistance Spot Welding of CR590T/340Y Galvanized Dual Phase Steel
Authors: Zhang Xinge , Yao Fubin , Ren Zhenan , Yu Haiyan
Published: November 2018

During resistance spot welding, the welding current is the most important process parameter, which determines the welding heat input and then has a great influence on the welding quality. In present study, the CR590T/340YDP galvanized dual phase steel widely used as automobile material was carried out using resistance spot welding. The effect of welding current on the weld formation, microstructure, and mechanical properties was studied in detail. It was found that the quality of weld appearance decreased with the increase of welding current, and there was a Zn island on the weld surface. The microstructure of the whole resistance spot welded joint was inhomogeneity. The nugget zone consisted of coarse lath martensite and a little of ferrite with the columnar crystal morphology, and the microstructure of weld nugget became coarser when the welding current was higher. There was an optimum welding current value and the tensile strength reached the maximum. This investigation will provide the process guidance for automobile body production.
Thrombolysis Enhancing by Magnetic Manipulation of Fe3O4 Nanoparticles
Authors: Li Qian , Liu Xiaojun , Chang Ming , Lu Zhen
Published: November 2018

In this paper, an effective method of accelerating urokinase-administrated thrombolysis through a rotating magnetic field (RMF) of guided magnetic nanoparticles (NPs) in the presence of low-dose urokinase is proposed. The dispersed Fe3O4 NPs mixed with urokinase were injected into microfluidic channels occluded by thrombus prepared in vitro. These magnetic NPs aggregated into elongated clusters under a static magnetic field, and were then driven by the RMF. The rotation of Fe3O4 aggregates produced a vortex to enhance the diffusion of urokinase to the surface of the thrombus and accelerate its dissolution. A theoretical model based on convective diffusion was constructed to describe the thrombolysis mechanism. The thrombus lysis speed was determined according to the change of the thrombus dissolution length with time in the microfluidic channel. The experimental results showed that the thrombolysis speed with rotating magnetic NPs is significantly increased by nearly two times compared with using the same dose of pure urokinase. This means that the magnetically-controlled NPs approach provides a feasible way to achieve a high thrombolytic rate with low-dose urokinase in use.
Plasmonic Metasurface Absorber Based on Electro-Optic Substrate for Energy Harvesting
Authors: Muhammad Naseer , Fu Tao , Liu Qiang , Tang Xiaopin , Deng Zi-Lan , Ouyang Zhengbiao
Published: November 2018

A highly efficient and broad light absorber capable of wide-angle absorption in the visible and near infrared range is presented and numerically investigated for energy harvesting in a simple geometry. According to the calculated results, the proposed device has a peak absorption level of about 99.95%. The actual absorption efficiency is 76.35%, which is approaching that of complex multilayer absorbers with 88 layers working in the wavelength range of 300 nm to 2000 nm. The electro-optic material has the potential of shifting the absorption peak position, compensating fabrication errors and thus reducing the fabrication technique difficulties. Also, the high electro-optic tunability can be used for filters, infrared detection, and imaging applications. More directly, the proposed absorber can be potentially deployed in solar cells and solar thermals.
Ordering of Primary Carbonitrides in an Austenitic Steel Revealed by Transmission Electron Microscopy and Atom Probe Tomography
Authors: Ou Ping , Li Zhiming
Published: November 2018

We reveal for the first time an ordering phenomenon of a type of carbonitrides in a Super304H austenitic steel via the techniques of transmission electron microscopy and atom probe tomography. Solution-treated Super304H austenitic steel samples containing a few primary carbonitrides were aged at 923 K for 5000 h. The results show that the primary carbonitrides in the Super304H steel are non-stoichiometric compounds enriched in Nb and with a NaCl-type structure. The crystal structure of the Nb-rich carbonitrides is in a disordered state in the solution-treated steel, while in an ordered state in the aged steel. This observation suggests the occurrence of a disorder–order structural transition in the primary carbonitrides during long-term aging. We found that such a disorder–order structural transition is accompanied by carbon diffusion from the primary carbonitrides into the austenitic matrix. The ordering phenomenon is discussed based on the long-range ordering of structure vacancies in the non-metal lattice of the superstructure, providing new insights for the understanding of ordering in non-stoichiometric compounds.
Design of Shape Memory Alloy Coil Spring Actuator for Improving Performance in Cyclic Actuation
Authors: Koh Je-sung
Published: November 2018

Performance of the shape memory alloy (SMA) coil spring actuator in cyclic actuation as an artificial muscle is strongly related to the mechanical design of the coil geometry. This paper proposes a practical design method for improving the frequency and efficiency of the SMA coil spring actuator; by designing the SMA coil spring to have large index (coil diameter/wire diameter) and pitch angle (LIP), cooling characteristics can be improved (increasing the actuation frequency) and large deformation can be obtained. The LIP design process is based on the two-state static model that describes the displacement-force relationship of the SMA coil spring in two states—a fully austenite phase and a fully martensite phase. The design process gives accurate design parameters of the SMA coil spring actuator that satisfy the required stroke and force. The model of the fully martensite phase of the SMA coil that includes the stress-induced detwinning enables the use of maximum shear strain of the SMA. The design method reduces the mass of an SMA without changing the stroke and increase the power density and efficiency. The cyclic actuation experiments demonstrate that the LIP design doubles the maximum frequency of SMA coil actuator with one-sixth the mass of the non-LIP design.
Evaluating the Effect of Hydrophobic Nanosilica on the Viscoelasticity Property of Asphalt and Asphalt Mixture
Authors: Guo Wei , Guo Xuedong , Chang Mengyuan , Dai Wenting
Published: November 2018

Viscoelasticity property of bitumen is closely related to the service life of bituminous pavement. This paper evaluated the impact of one of the most efficient and widely used nanomaterials in various industries called hydrophobic nanosilica on the viscoelasticity property of bitumen and asphalt mixture. In this paper, three hydrophobic nanosilica modified bitumens and asphalt mixtures were researched by conventional physical properties test, SEM test, FTIR test, DSC test, DSR test, static creep test and dynamic creep test. The results showed that the introduction of hydrophobic nanosilica could strengthen the viscosity of asphalt more effectively and had better dispersion than hydrophilic nanosilica in asphalt. From conventional physical properties test and rheological performance test, hydrophobic nanosilica could weaken the temperature susceptibility of bitumen observably. From DSR test, hydrophobic nanosilica modified asphalt had a lower sensitivity and dependence on temperature and frequency than hydrophilic nanosilica modified asphalt. The Cole–Cole diagrams indicated that hydrophobic nanosilica exhibited good compatibility with asphalt compared with hydrophilic nanosilica. Newly formed chemical bonds were found in the hydrophobic nanosilica modified asphalt and its mixture with stone according to SEM test, FTIR test, and DSC test, which is the biggest difference from the modification mechanism of hydrophilic nanosilica modified asphalt. Through static and dynamic creep test, it found that the addition of hydrophobic nanosilica can significantly reduce the creep strain at the same temperature.
Common Fixed Points for Mappings under Contractive Conditions of (α,β,ψ)-Admissibility Type
Authors: Shatanawi Wasfi
Published: November 2018

In this paper, we introduce the notion of ( α , β , ψ ) -contraction for a pair of mappings ( S , T ) defined on a set X. We use our new notion to create and prove a common fixed point theorem for two mappings defined on a metric space ( X , d ) under a set of conditions. Furthermore, we employ our main result to get another new result. Our results are modifications of many existing results in the literature. An example is included in order to show the authenticity of our main result.
Scheduling and Planning in Service Systems with Goal Programming: Literature Review
Authors: Gür Şeyda , Eren Tamer
Published: November 2018

Background: People want to be able to evaluate different kinds of information in a good way. There are various methods that they develop in such situations. Among the optimization methods, the goal programming method is often used when there are multiple objectives that decision makers want to accomplish. Because scheduling and planning problems have multiple objectives that are desired to be achieved, the goal programming method helps the researcher in contradictory situations between these goals. Methods: This study includes, examines, and analyzes recent research on service scheduling and planning. In the literature, service scheduling and planning studies have been examined using goal programming method from past to today. Results: The studies are detailed according to the type of goal programming, according to scheduling types, the purpose used in the studies, and the methods integrated with the goal programming. There are 142 studies in Emerald, Science Direct, Jstor, Springer, Taylor and Francis, Google Scholar, etc. databases that are examined in detail. For readers, diversification has been made to facilitate the identification of these studies and a detailed overview has been presented. Conclusion: As a result of the study, studies with the goal programming in the literature have been seen. The readers’ perspectives for planning and scheduling are discussed.
Chitosan Oligosaccharides Improve Glucolipid Metabolism Disorder in Liver by Suppression of Obesity-Related Inflammation and Restoration of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ)
Authors: Bai Yibo , Zheng Junping , Yuan Xubing , Jiao Siming , Feng Cui , Du Yuguang , Liu Hongtao , Zheng Lanyan
Published: November 2018

Chitosan oligosaccharides (COS) display various biological activities. In this study, we aimed to explore the preventive effects of COS on glucolipid metabolism disorder using palmitic acid (PA)-induced HepG2 cells and high-fat diet (HFD)-fed C57BL/6J mice as experimental models in vitro and in vivo, respectively. The results showed that COS pretreatment for 12 h significantly ameliorated lipid accumulation in HepG2 cells exposed to PA for 24 h, accompanied by a reversing of the upregulated mRNA expression of proinflammatory cytokines (IL-6, MCP-1, TNF-α) and glucolipid metabolism-related regulators (SCD-1, ACC1, PCK1-α). In addition, COS treatment alleviated glucolipid metabolism disorder in mice fed with HFD for five months, including reduction in body weight and fasting glucose, restoration of intraperitoneal glucose tolerance, and suppression of overexpression of proinflammatory cytokines and glucolipid metabolism-related regulators. Furthermore, our study found that COS pretreatment significantly reversed the downregulation of PPARγ at transcriptional and translational levels in both PA-induced HepG2 cells and liver tissues of HFD-fed mice. In summary, the study suggests that COS can improve glucolipid metabolism disorder by suppressing inflammation and upregulating PPARγ expression. This indicates a novel application of COS in preventing and treating glucolipid metabolism-related diseases.
Role of Nanocomposite Support Stiffness on TFC Membrane Water Permeance
Authors: Idarraga-Mora Jaime A. , Childress Anthony S. , Friedel Parker S. , Ladner David A. , Rao Apparao , Husson Scott
Published: November 2018

This paper discusses the role played by the mechanical stiffness of porous nanocomposite supports on thin-film composite (TFC) membrane water permeance. Helically coiled and multiwall carbon nanotubes (CNTs) were studied as additives in the nanocomposite supports. Mechanical stiffness was evaluated using tensile tests and penetration tests. While a low loading of CNTs caused macrovoids that decreased the structural integrity, adding higher loads of CNTs compensated for this effect, and this resulted in a net increase in structural stiffness. It was found that the Young’s modulus of the nanocomposite supports increased by 30% upon addition of CNTs at 2 wt %. Results were similar for both types of CNTs. An empirical model for porous composite materials described the Young’s modulus results. The nanocomposite supports were subsequently used to create TFC membranes. TFC membranes with stiffer supports were more effective at preventing declines in water permeance during compression. These findings support the idea that increasing the mechanical stiffness of TFC membrane nanocomposite supports is an effective strategy for enhancing water production in desalination operations.
Intensified LOHC-Dehydrogenation Using Multi-Stage Microstructures and Pd-Based Membranes
Authors: Wunsch Alexander , Mohr Marijan , Pfeifer Peter
Published: November 2018

Liquid organic hydrogen carriers (LOHC) are able to store hydrogen stably and safely in liquid form. The carrier can be loaded or unloaded with hydrogen via catalytic reactions. However, the release reaction brings certain challenges. In addition to an enormous heat requirement, the released hydrogen is contaminated by traces of evaporated LOHC and by-products. Micro process engineering offers a promising approach to meet these challenges. In this paper, a micro-structured multi-stage reactor concept with an intermediate separation of hydrogen is presented for the application of perhydro-dibenzyltoluene dehydrogenation. Each reactor stage consists of a micro-structured radial flow reactor designed for multi-phase flow of LOHC and released hydrogen. The hydrogen is separated from the reactors’ gas phase effluent via PdAg-membranes, which are integrated into a micro-structured environment. Separate experiments were carried out to describe the kinetics of the reaction and the separation ability of the membrane. A model was developed, which was fed with these data to demonstrate the influence of intermediate separation on the efficiency of LOHC dehydrogenation.
Influence of Passivation Layers on Positive Gate Bias-Stress Stability of Amorphous InGaZnO Thin-Film Transistors
Authors: Zhou Yan , Dong Chengyuan
Published: November 2018

Passivation (PV) layers could effectively improve the positive gate bias-stress (PGBS) stability of amorphous InGaZnO (a-IGZO) thin-film transistors (TFTs), whereas the related physical mechanism remains unclear. In this study, SiO2 or Al2O3 films with different thicknesses were used to passivate the a-IGZO TFTs, making the devices more stable during PGBS tests. With the increase in PV layer thickness, the PGBS stability of a-IGZO TFTs improved due to the stronger barrier effect of the PV layers. When the PV layer thickness was larger than the characteristic length, nearly no threshold voltage shift occurred, indicating that the ambient atmosphere effect rather than the charge trapping dominated the PGBS instability of a-IGZO TFTs in this study. The SiO2 PV layers showed a better improvement effect than the Al2O3 because the former had a smaller characteristic length (~5 nm) than that of the Al2O3 PV layers (~10 nm).
Method of Calculating the Inductance Value of MEMS Suspended Inductors with Silicon Substrates
Authors: Li Yiyuan , Li Jianhua , Xu Lixin
Published: November 2018

Microelectromechanical system (MEMS) suspended inductors have excellent radio-frequency (RF) performance. The inductance value is one of the main features that characterizes the performance of inductors. It is important to consider the influence of the substrate and the suspension height in calculating the inductance value accurately. In this paper, a method is proposed to calculate the inductance value of the MEMS suspended inductor wire with a silicon substrate, as the wire is the basic component of the inductor coil. Then the method is extended to the suspended inductors consisting of a single turn coil. The calculation results obtained by this proposed method were verified by finite-element analysis (HFSS) and they were found to agree well with the results of the HFSS simulation.
Editorial for Special Issue on Flexible Electronics: Fabrication and Ubiquitous Integration
Authors: Martinez Ramses V.
Published: November 2018

Based on the premise “anything thin is flexible”, the field of flexible electronics has been fueled from the ever-evolving advances in thin-film materials and devices. [...]
Calibration of a Constitutive Model from Tension and Nanoindentation for Lead-Free Solder
Authors: Long Xu , Zhang Xiaodi , Tang Wenbin , Wang Shaobin , Feng Yihui , Chang Chao
Published: November 2018

It is challenging to evaluate constitutive behaviour by using conventional uniaxial tests for materials with limited sizes, considering the miniaturization trend of integrated circuits in electronic devices. An instrumented nanoindentation approach is appealing to obtain local properties as the function of penetration depth. In this paper, both conventional tensile and nanoindentation experiments are performed on samples of a lead-free Sn–3.0Ag–0.5Cu (SAC305) solder alloy. In order to align the material behaviour, thermal treatments were performed at different temperatures and durations for all specimens, for both tensile experiments and nanoindentation experiments. Based on the self-similarity of the used Berkovich indenter, a power-law model is adopted to describe the stress–strain relationship by means of analytical dimensionless analysis on the applied load-penetration depth responses from nanoindentation experiments. In light of the significant difference of applied strain rates in the tensile and nanoindentation experiments, two “rate factors” are proposed by multiplying the representative stress and stress exponent in the adopted analytical model, and the corresponding values are determined for the best predictions of nanoindentation responses in the form of an applied load–indentation depth relationship. Eventually, good agreement is achieved when comparing the stress–strain responses measured from tensile experiments and estimated from the applied load–indentation depth responses of nanoindentation experiments. The rate factors ψ σ and ψ n are calibrated to be about 0.52 and 0.10, respectively, which facilitate the conversion of constitutive behaviour from nanoindentation experiments for material sample with a limited size.
Lead–Antimony Sulfosalts from Tuscany (Italy). XXIV. Crystal Structure of Thallium-Bearing Chovanite, TlPb26(Sb,As)31S72O, from the Monte Arsiccio Mine, Apuan Alps
Authors: Biagioni Cristian , Moëlo Yves , Perchiazzi Natale , Demitri Nicola , Lepore Giovanni Orazio
Published: November 2018

A thallium-bearing variety of the lead–antimony oxysulfosalt chovanite from the Monte Arsiccio mine (Apuan Alps, Tuscany, Italy) has been reexamined. It occurs as thin, ribbon-like crystals, black in color, up to 5 mm in length in vugs of dolomite ± baryte ± quartz veins embedded in the metadolostone of the Sant’Olga level. Associated minerals are rouxelite, robinsonite, sphalerite, valentinite, baryte, dolomite, quartz, and Ba-rich K-feldspar. Chemical analysis pointed to contents of Tl up to 0.86 apfu, corresponding to the ideal chemical formula TlPb26(Sb,As)31S72O. The structural role of thallium has been investigated using single-crystal X-ray diffraction using synchrotron radiation (λ = 0.59040 Å). Thallium-rich chovanite is monoclinic, space group P21/c, with unit-cell parameters a = 34.280(3), b = 8.2430(7), c = 48.457(4) Å, β = 106.290(4)°, and V = 13143(2) Å3. The crystal structure was refined to a final R1 = 0.083 for 12,052 reflections with Fo > 4σ(Fo) and 1210 refined parameters. The general features of thallium-rich chovanite agree with those of chovanite. Thallium is present as Tl+; it is disordered among two mixed (Pb/Tl) positions, with a Tl/Pb atomic ratio below 1, that precludes this compound to be a new species.
Six New Phragmalin Limonoids from the Stems of Chukrasia tabularis A. Juss
Authors: Wang Yan-Cui , Kong Fan-Dong , Wang Hao , Mei Wen-Li , Liu Shou-Bai , Zhao You-Xing , Dai Hao-Fu
Published: November 2018

Six new phragmalin limonoids, named moluccensin Z1 (1), moluccensin Z2 (2), carapanolide Y (3), tabulalin N (4), chukvelutilide A1 (5), and velutinasin J (6), as well as two known compounds, chukvelutilide A (7) and velutinasin D (8) were isolated from the stems of Chukrasia tabularis A. Juss. The structures of the new compounds 1–6 were confirmed by spectroscopic methods, including IR and HRESIMS, as well as 1D and 2D NMR, and by comparisons with the data of known analogues. All compounds were tested for α-glucosidase and acetylcholinesterase inhibitory activities. However, none of the compounds was active against α-glucosidase and acetylcholinesterase in vitro.
In-Situ Preparation of CdTe Quantum Dots Capped with a β-Cyclodextrin-Epichlorohydrin Polymer: Polymer Influence on the Nanocrystal’s Optical Properties
Authors: Martin-Trasanco Rudy , Esparza-Ponce Hilda E. , Ortiz Pedro D. , Oyarzun Diego P. , Zuñiga Cesar , Montero-Cabrera Maria E. , Tundidor-Camba Alain , Pizarro Guadalupe del C. , Arratia-Pérez Ramiro
Published: November 2018

β-Cyclodextrin (βCD), the less water soluble of the cyclodextrins, has been used as a capping agent in the preparation of semiconductor nanocrystals or quantum dots (QDs). Nevertheless, no reports have been found in the use of the highly water-soluble polymer of this, prepared by the crosslinking of the βCD units with epichlorohydrin in basic medium (βCDP). This polymer, besides to overcome the low solubility of the βCD, increases the inclusion constant of the guest; two parameters that deserve its use as capping agent, instead of the native cyclodextrin. In the present manuscript, we afforded the in-situ aqueous preparation of cadmium telluride (CdTe) QDs capped with βCDP. The polymer influence on the photoluminescent properties of the nanocrystals was analyzed. The βCDP controls the nanocrystals growth during the Oswald ripening stage. Consequently, the CdTe capped βCDP QDs showed lower Stokes-shift values, higher photoluminescent efficiency, and narrower size distribution than for nanocrystals obtained in the absence of polymer. Transmission electron microscopy (TEM) micrographs and energy dispersive X-ray spectroscopy (EDS) analysis revealed the composition and crystallinity of the CdTe QDs. This βCDP capped CdTe QDs is a potential scaffold for the supramolecular modification of QDs surface.
Long Non-Coding RNA Modulation of VEGF-A during Hypoxia
Authors: Nieminen Tiina , Scott Tristan A. , Lin Feng-Mao , Chen Zhen , Yla-Herttuala Seppo , Morris Kevin V.
Published: November 2018

The role and function of long non-coding RNAs (lncRNAs) in modulating gene expression is becoming apparent. Vascular endothelial growth factor A (VEGF-A) is a key regulator of blood vessel formation and maintenance making it a promising therapeutic target for activation in ischemic diseases. In this study, we uncover a functional role for two antisense VEGF-A lncRNAs, RP1-261G23.7 and EST AV731492, in transcriptional regulation of VEGF-A during hypoxia. We find here that both lncRNAs are polyadenylated, concordantly upregulated with VEGF-A, localize to the VEGF-A promoter and upstream elements in a hypoxia dependent manner either as a single-stranded RNA or DNA bound RNA, and are associated with enhancer marks H3K27ac and H3K9ac. Collectively, these data suggest that VEGF-A antisense lncRNAs, RP1-261G23.7 and EST AV731492, function as VEGF-A promoter enhancer-like elements, possibly by acting as a local scaffolding for proteins and also small RNAs to tether.
The Effect of an Encapsulated Nutrient Mixture on Food Intake and Satiety: A Double-Blind Randomized Cross-Over Proof of Concept Study
Authors: Alleleyn Annick M. E. , Van Avesaat Mark , Ripken Dina , Bleiel Sinéad B. , Keszthelyi Daniel , Wilms Ellen , Troost Freddy J. , Hendriks Henk F. J. , Masclee Adrian A. M.
Published: November 2018

Activation of the intestinal brake by infusing nutrients into the distal small intestine with catheters inhibits food intake and enhances satiety. Encapsulation of macronutrients, which protects against digestion in the proximal gastrointestinal tract, can be a non-invasive alternative to activate this brake. In this study, we investigate the effect of oral ingestion of an encapsulated casein and sucrose mixture (active) targeting the distal small intestine versus a control product designed to be released in the stomach on food intake, satiety, and plasma glucose concentrations. Fifty-nine volunteers received the active and control product on two separate test days. Food intake was determined during an ad libitum meal 90 min after ingestion of the test product. Visual analogue scale scores for satiety and blood samples for glucose analysis were collected at regular intervals. Ingestion of the active product decreased food intake compared to the control product (655 kcal compared with 699 kcal, respectively, p < 0.05). The area under the curve (AUC) for hunger was decreased (p < 0.05) and AUC for satiety was increased (p < 0.01) after ingestion of the active product compared to the control product. Ingestion of an encapsulated protein-carbohydrate mixture resulted in inhibition of food intake compared to a non-encapsulated control product.
Does Village Chicken-Keeping Contribute to Young Children’s Diets and Growth? A Longitudinal Observational Study in Rural Tanzania
Authors: De Bruyn Julia , Thomson Peter C. , Darnton-Hill Ian , Bagnol Brigitte , Maulaga Wende , Alders Robyn G.
Published: November 2018

There is substantial current interest in linkages between livestock-keeping and human nutrition in resource-poor settings. These may include benefits of improved diet quality, through animal-source food consumption and nutritious food purchases using livestock-derived income, and hazards of infectious disease or environmental enteric dysfunction associated with exposure to livestock feces. Particular concerns center on free-roaming chickens, given their proximity to children in rural settings, but findings to date have been inconclusive. This longitudinal study of 503 households with a child under 24 months at enrolment was conducted in villages of Manyoni District, Tanzania between May 2014, and May 2016. Questionnaires encompassed demographic characteristics, assets, livestock ownership, chicken housing practices, maternal education, water and sanitation, and dietary diversity. Twice-monthly household visits provided information on chicken numbers, breastfeeding and child diarrhea, and anthropometry was collected six-monthly. Multivariable mixed model analyses evaluated associations between demographic, socioeconomic and livestock-associated variables and (a) maternal and child diets, (b) children’s height-for-age and (c) children’s diarrhea frequency. Alongside modest contributions of chicken-keeping to some improved dietary outcomes, this study importantly (and of substantial practical significance if confirmed) found no indication of a heightened risk of stunting or greater frequency of diarrhea being associated with chicken-keeping or the practice of keeping chickens within human dwellings overnight.
Feedback-Based Treatments for Eating Disorders and Related Symptoms: A Systematic Review of the Literature
Authors: Imperatori Claudio , Mancini Miranda , Della Marca Giacomo , Valenti Enrico Maria , Farina Benedetto
Published: November 2018

The effectiveness of biofeedback and neurofeedback has been investigated in a range of psychiatric disorders. However, to date, there are few studies on the clinical usefulness of feedback-based techniques for eating disorders (EDs) and EDs-related symptoms (e.g., food craving). A systematic search of PubMed, Scopus and PsychINFO identified 162 articles. Among these, thirteen studies exploring the therapeutic use of biofeedback and neurofeedback in EDs or EDs-related symptoms were included. Biofeedback and neurofeedback were implemented respectively in five and eight of all reviewed articles. No studies incorporated different feedback modalities or both biofeedback and neurofeedback. The considered studies provide preliminary data of the usefulness of feedback-based techniques in the treatment of several dysfunctional eating behaviors (e.g., food craving, rumination). Although no significant effect has been reported for other important EDs-related symptoms (i.e., body image disturbance), feedback-based techniques are also associated with significant modifications of both sympathetic reaction to food-related stimuli and brain activity in several regions of the reward system (e.g., insula). Taken together the results of the present review suggest that feedback-based treatments may be useful in the treatment of several dysfunctional eating behaviors operating both on top-down and bottom-up individual coping strategies. Methodological and clinical issues are also discussed.
Within-Day Amino Acid Intakes and Nitrogen Balance in Male Collegiate Swimmers during the General Preparation Phase
Authors: Matsuda Takeshi , Kato Hiroyuki , Suzuki Haruka , Mizugaki Ami , Ezaki Takahiko , Ogita Futoshi
Published: November 2018

A higher protein intake is recommended for athletes compared to healthy non-exercising individuals. Additionally, the distribution and quality (i.e., leucine content) of the proteins consumed throughout the day should be optimized. This study aimed to determine the nitrogen balance and distribution of protein and amino acid intakes in competitive swimmers during the general preparation phase. Thirteen swimmers (age: 19.7 ± 1.0 years; VO2max: 63.9 ± 3.7 mL·kg−1·min−1, mean ± standard deviation) participated in a five-day experimental training period. Nutrient intakes were assessed using dietary records. Nitrogen balance was calculated from the daily protein intake and urinary nitrogen excretion. The intake amounts of amino acids and protein at seven eating occasions were determined. The average and population-safe intakes for zero nitrogen balance were estimated at 1.43 and 1.92 g·kg−1·day−1, respectively. The intake amounts of protein and leucine at breakfast, lunch, and dinner satisfied current guidelines for the maximization of muscle protein synthesis, but not in the other four occasions. The population-safe protein intake level in competitive swimmers was in the upper range (i.e., 1.2–2.0 g·kg−1·day−1) of the current recommendations for athletes. The protein intake distribution and quality throughout the day may be suboptimal for the maximization of the skeletal muscle adaptive response to training.
Anionic Long-Circulating Quantum Dots for Long-Term Intravital Vascular Imaging
Authors: Wang Haolu , Yang Haotian , Xu Zhi Ping , Liu Xin , Roberts Michael S. , Liang Xiaowen
Published: November 2018

A major impediment to the long-term in vivo vascular imaging is a lack of suitable probes and contrast agents. Our developed mercaptosuccinic acid (MSA) capped cadmium telluride/cadmium sulfide (CdTe/CdS) ultrasmall quantum dots (QDs) have high fluorescent quantum yield, long fluorescence lifetime and long half-life in blood, allowing high resolution long-term intravital vascular imaging. In this study, we showed that these QDs can be used to visualize the in vivo the vasculature in normal and cancerous livers in mice using multiphoton microscopy (MPM) coupled with fluorescence lifetime imaging (FLIM), with cellular resolution (~1 µm) up to 36 h after intravenous injection. Compared to highly regulated and controlled sinusoids in normal liver tissue, disordered, tortuous, and immature neovessels were observed in tumors. The utilized imaging methods have great potential as emerging tools in diagnosis and monitoring of treatment response in cancer.
Hylomorphism Extended: Dynamical Forms and Minds
Authors: Duch Włodzisław
Published: November 2018

Physical objects are compounds of matter and form, as stated by Aristotle in his hylomorphism theory. The concept of “form” in this theory refers to physical structures or organizational structures. However, mental processes are not of this kind, they do not change physical arrangement of neurons, but change their states. To cover all natural processes hylomorphism should acknowledge differences between three kinds of forms: Form as physical structure, form as function resulting from organization and interactions between constituent parts, and dynamical form as state transitions that change functions of structures without changing their physical organization. Dynamical forms, patterns of energy activation that change the flow of information without changing the structure of matter, are the key to understand minds of rational animals.
Philosophia Naturalis Rediviva: Natural Philosophy for the Twenty-First Century
Authors: MacLennan Bruce J.
Published: November 2018

A revitalized practice of natural philosophy can help people to live a better life and promote a flourishing ecosystem. Such a philosophy is natural in two senses. First, it is natural by seeking to understand the whole of nature, including mental phenomena. Thus, a comprehensive natural philosophy should address the phenomena of sentience by embracing first- and second-person methods of investigation. Moreover, to expand our understanding of the world, natural philosophy should embrace a full panoply of explanations, similar to Aristotle’s four causes. Second, such a philosophy is natural by being grounded in human nature, taking full account of human capacities and limitations. Future natural philosophers should also make use of all human capacities, including emotion and intuition, as well as reason and perception, to investigate nature. Finally, since the majority of our brain’s activities are unconscious, natural philosophy should explore the unconscious mind with the aim of deepening our relation with the rest of nature and of enhancing well-being.
Isothermal Crystallization and Rheology Properties of Isotactic Polypropylene/Bacterial Cellulose Composite
Authors: Wang Bo , Lin Fu-hua , Li Xiang-yang , Zhang Zhong-wei , Xue Xiao-rong , Liu Si-xiao , Ji Xu-ran , Yu Qian , Yuan Zheng-qiu , Chen Xin-de , Luo Jun
Published: November 2018

Bacterial cellulose (BC) is a new kind of cellulose with great potential in enhancing preparation of isotactic Polypropylene (iPP) composites, which have been found with excellent performance. However, the interface compatibility between BC and iPP is poor. In this study, iPP/BC composites were prepared by solution mixing. Esterification modified BC (CO) and Maleic anhydride grafted polypropylene (MAPP) added as a compatibilizer was both used to improve the interfacial compatibility of the iPP/BC composites. The rheology and isothermal crystallization behavior of the composites was tested and discussed. The result shows that the complex viscosity and storage modulus of the composite significantly increase in the rule iPP, iPP/BC2, iPP/CO2, and M-iPP/BC3, which indicates that the compatibility of the composite increases as this rule. According to the isothermal crystallization kinetics result, the crystal growth mode of iPP was not affected by the addition of BC and the interfacial compatibility. The spherulite growth rate of the iPP/BC composite increases with increasing crystallization temperature. Especially, the value decreases as the same rule with the complex viscosity and storage modulus of the composite at the same isothermal crystallization temperature. These results suggest that the interface compatibility of iPP/BC composites is greatly improved and the interface compatibility of the M-iPP/BC3 is better than the iPP/CO2.
Application of Laser-Induced Fluorescence in Functional Studies of Photosynthetic Biofilms
Authors: Marques da Silva Jorge , Borissovitch Utkin Andrei
Published: November 2018

Biofilms are a ubiquitous form of life for microorganisms. Photosynthetic biofilms such as microphytobenthos (MPB) and biological soil crusts (BSC) play a relevant ecological role in aquatic and terrestrial ecosystems, respectively. On the other hand, photosynthetic epilithic biofilms (PEB) are major players in the microbial-induced decay of stone structures of cultural heritage. The use of fluorescence techniques, namely, pulse-amplitude-modulated fluorometry, was crucial to understanding the photophysiology of these microbial communities, since they made it possible to measure biofilms’ photosynthetic activity without disturbing their delicate spatial organization within sediments or soils. The use of laser-induced fluorescence (LIF) added further technical advantages, enabling measurements to be made at a considerable distance from the samples, and under daylight. In this Perspective, we present state-of-the-art LIF techniques, show examples of the application of LIF to MPB and present exploratory results of LIF application to BSC, as well as to PEB colonizing stone structures of cultural heritage. Thereafter, we discuss the perspectives of LIF utilization in environmental research and monitoring, in cultural heritage conservation and assessment, and in biotechnological applications of photosynthetic biofilms.
Alternative Approach to Current EU BAT Recommendation for Coal-Fired Power Plant Flue Gas Desulfurization Wastewater Treatment
Authors: Bogacki Jan , Marcinowski Piotr , Majewski Maciej , Zawadzki Jarosław , Sivakumar Sridhar
Published: November 2018

Fossil fuel combustion is a serious environmental problem. Significant quantities of flue gasses and wastewater, requiring further treatment, are produced. This article compares three wet flue gas desulfurization (FGD) wastewater treatment methods: coagulation with precipitation using iron(III) ions—recommended by the European Union as the best available technique (BAT)—and two alternative advanced oxidation processes (Fe2+/H2O2 and Fe0/H2O2). Both oxidation processes that were used met the technical FGD wastewater treatment requirements of the BAT. The best treatment effects, expressed as pollutants’ removal, were obtained for the Fe2+/H2O2 process for 150/300 mg/L reagent doses. It allows effective removal of boron up to 212 mg/L and heavy metals up to below the detection limit <0.010 mg/L for Pb and <0.005 mg/L for Cu. Therefore, the Fe2+/H2O2 process could be an option for FGD wastewater treatment as an alternative to the BAT recommended iron(III)-based coagulation with precipitation. Additionally, an analysis of variance was applied to check the significance of the two independent variables and their interactions. Statistical analysis confirmed high efficiency and applicability of treatment process.
Fault Detection in Wastewater Treatment Systems Using Multiparametric Programming
Authors: Che Mid Ernie , Dua Vivek
Published: November 2018

In this work, a methodology for fault detection in wastewater treatment systems, based on parameter estimation, using multiparametric programming is presented. The main idea is to detect faults by estimating model parameters, and monitoring the changes in residuals of model parameters. In the proposed methodology, a nonlinear dynamic model of wastewater treatment was discretized to algebraic equations using Euler’s method. A parameter estimation problem was then formulated and transformed into a square system of parametric nonlinear algebraic equations by writing the optimality conditions. The parametric nonlinear algebraic equations were then solved symbolically to obtain the concentration of substrate in the inflow, S c i n , inhibition coefficient, K i , and specific growth rate, μ o , as an explicit function of state variables (concentration of biomass, X ; concentration of organic matter, S c ; concentration of dissolved oxygen, S o ; and volume, V ). The estimated model parameter values were compared with values from the normal operation. If the residual of model parameters exceeds a certain threshold value, a fault is detected. The application demonstrates the viability of the approach, and highlights its ability to detect faults in wastewater treatment systems by providing quick and accurate parameter estimates using the evaluation of explicit parametric functions.
Karl Rahner and the Elusive Search for Christian Unity
Authors: Dart Eric S.
Published: November 2018

Despite his prominence within the landscape of theology, Karl Rahner is largely absent in ecumenical discourse. This is surprising considering the concern he shows for both the church’s unity and ecumenism throughout his writings. Rahner’s understanding of unity and diversity and their relationship to one another has the potential to provide important resources for the contemporary ecumenical movement and the goal of visible unity. This article examines Karl Rahner’s theological understanding of ecumenism and the relationship of ecumenism to the realities of unity and diversity. This article explicates Rahner’s theologies of symbol and unity as prerequisites for understanding and developing the relationship between unity and diversity. The unity of the Church is fundamentally a symbolic reality in the process of “becoming”.