bluuebunny/crossref_metadata_2025 huggingface dataset:
Noise annoyance and risk of prevalent and incident atrial fibrillation–A sex-specific analysis
Authors: Hahad Omar , Beutel Manfred E. , Gilan Donya A. , Chalabi Julian , Schuster Alexander K. , Gianicolo Emilio , Lackner Karl J. , Lieb Klaus , Galle Peter R. , Wild Philipp S. , Daiber Andreas , Münzel Thomas
Published: December 2022

Background

While chronic exposure to high levels of noise was demonstrated to increase the risk of various cardiovascular diseases, the association between noise annoyance and risk of cardiovascular disease remains still inconsistent. Recently, we showed that noise annoyance is associated with prevalent atrial fibrillation in the general population. However, the association between noise annoyance and risk of incident atrial fibrillation as well as potential sex-differences remain still elusive.

Methods and results

15,010 subjects from a German population-based cohort were examined at baseline (2007 to 2012) and follow-up five years later (2012 to 2017) to investigative the association between noise annoyance due to multiple sources and prevalent and incident atrial fibrillation. After multivariable adjustment, the results from logistic regression analyses revealed overall consistent and positive associations between noise annoyance and prevalent and incident atrial fibrillation in men, whereas this association was weaker in women, in particular with respect to incident atrial fibrillation. For instance, industrial noise annoyance was associated with 21% (95% confidence interval (CI) 9–34%) and 18% (8–29%) higher odds of prevalent atrial fibrillation in men and women, respectively. In prospective analysis, this association remained stable in men (odds ratio (OR) 1.25, 1.07–1.44), while in women no association was observed (OR 1.03, 0.89–1.18).

Conclusions

The findings suggest that noise annoyance can increase the risk of incident atrial fibrillation in a large population-based cohort and that men may be more sensitive to the adverse effects of noise annoyance with regard to the risk of atrial fibrillation.
Association of the consumption of common drinks with early puberty in both sexes
Authors: Tsai Meng-Che , Lee Yungling Leo , Chen Yang Ching
Published: December 2022

Background

We examined the effect of sugar-sweetened beverages (SSB) and common drink intake on pubertal development in both sexes.

Methods

Data were retrieved from Taiwan Children Health Study, which involved detailed pubertal stage assessments of 2,819 schoolchildren aged 11 years in 2011–2012. Drawings of secondary sexual characteristics and self-reported age at menarche or voice breaking were used to assess pubertal stages. Dietary intake was assessed using a detailed semi-quantitative food frequency questionnaire. Generalized estimating equation modeling was applied to obtain odds ratios (ORs) and 95% confidence intervals (CIs) to represent the effects of each drink on early pubertal development outcomes.

Results

In boys, an one cup/day increment of a SSB was associated with earlier voice breaking (β = −0.12; 95% CI = −0.20, −0.04), whereas consuming yogurt (≥2 cups/day) was a protective factor against early puberty (OR = 0.78; 95% CI = 0.73, 0.83). In girls, SSB consumption was associated with increased risk of early puberty in a dose–response manner, and a similar protective effect of yogurt consumption and fermented probiotic drink (≥2 cups/day) against early puberty was observed (OR = 0.96; 95% CI = 0.94, 0.99). Furthermore, the intake of both total sugar and added sugar within SSBs increased risk of early puberty in girls but not in boys.

Conclusions

Sugar-sweetened beverages were associated with early puberty, and probiotic drinks appeared to mitigate this link. These findings indicate that the gut–brain axis could play a crucial role in sexual maturation.
Case report: Chronic lymphocytic leukemia/small lymphocytic lymphoma and monomorphic epitheliotropic intestinal T-cell lymphoma: A composite lymphoma
Authors: Zhang Bing , Zhang Yangyang , Li Quan , Jiang Qingjun , Chu Wei , Gong Haifeng , Li Ruyuan , Ji Hong
Published: December 2022

Background: Composite lymphomas involving B-cell and T-cell lymphomas is very rare.

Case presentation: We reported a 63-year-old gentleman with composite chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL). The patient was admitted to our hospital due to abdominal pain, and was diagnosed with CLL/SLL after bone marrow (BM) biopsy, BM aspiration, and flow cytometry. Two weeks later, he was diagnosed with MEITL based on pathological analysis after intestine excision. Next gene sequencing (NGS) findings identified two hotspot mutation sites (STAT5B and DNMT3A) closely related with the pathogenesis of CLL/SLL and MEILT. Additionally, BCOR mutation was only detected in the CLL/SLL area. The likely pathogenic mutations of CLL were SETD2, NOTCH1, SF3B1, and PTPN11, while the likely pathogenic mutations related with the MEILT were TET2 and ZRSR2. Mutations of GATA3, PLCG2, and FAT1 were identified in both CLL/SLL and MEITL areas, but the clinical significance was unknown. Finally, the patient died in the 12-month follow-up after surgery.

Conclusion: We report a rare case of composite CLL/SLL and MEITL that highlights the importance of careful inspection of hematologic neoplasms. We also present the results of NGS of different gene mutations in CLL and MEITL tissues.
An innovative pyroptosis-related long-noncoding-RNA signature predicts the prognosis of gastric cancer via affecting immune cell infiltration landscape
Authors: Xiong Siping , Jin Long , Zeng Chao , Ma Hongmei , Xie Linying , Liu Shuguang
Published: December 2022

Background: Gastric cancer (GC) is a worldwide popular malignant tumor. However, the survival rate of advanced GC remains low. Pyroptosis and long non-coding RNAs (lncRNAs) are important in cancer progression. Thus, we aimed to find out a pyroptosis-related lncRNAs (PRLs) signature and use it to build a practical risk model with the purpose to predict the prognosis of patients with GC.

Methods: Univariate Cox regression analysis was used to identify PRLs linked to GC patient’s prognosis. Subsequently, to construct a PRLs signature, the least absolute shrinkage and selection operator regression, and multivariate Cox regression analysis were used. Kaplan–Meier analysis, principal component analysis, and receiver operating characteristic curve analysis were performed to assess our novel lncRNA signature. The correlation between risk signature and clinicopathological features was also examined. Finally, the relationship of pyroptosis and immune cells were evaluated through the CIBERSORT tool and single-sample lncRNA set enrichment analysis (ssGSEA).

Results: A PRLs signature comprising eight lncRNAs was discerned as a self-determining predictor of prognosis. GC patients were sub-divided into high-risk and low-risk groups via this risk-model. Stratified analysis of different clinical factors also displayed that the PRLs signature was a good prognosis factor. According to the risk score and clinical characteristics, a nomogram was established. Moreover, the difference between the groups is significance in immune cells and immune pathways.

Conclusion: This study established an effective prognostic signature consist of eight PRLs in GC, and constructed an efficient nomogram model. Further, the PRLs correlated with immune cells and immune pathways.
Exposure to Antibiotics and Neurodevelopmental Disorders: Could Probiotics Modulate the Gut–Brain Axis?
Authors: Diamanti Tamara , Prete Roberta , Battista Natalia , Corsetti Aldo , De Jaco Antonella
Published: December 2022

In order to develop properly, the brain requires the intricate interconnection of genetic factors and pre-and postnatal environmental events. The gut–brain axis has recently raised considerable interest for its involvement in regulating the development and functioning of the brain. Consequently, alterations in the gut microbiota composition, due to antibiotic administration, could favor the onset of neurodevelopmental disorders. Literature data suggest that the modulation of gut microbiota is often altered in individuals affected by neurodevelopmental disorders. It has been shown in animal studies that metabolites released by an imbalanced gut–brain axis, leads to alterations in brain function and deficits in social behavior. Here, we report the potential effects of antibiotic administration, before and after birth, in relation to the risk of developing neurodevelopmental disorders. We also review the potential role of probiotics in treating gastrointestinal disorders associated with gut dysbiosis after antibiotic administration, and their possible effect in ameliorating neurodevelopmental disorder symptoms.
Selenium and Its Compounds in the Treatment of Anxiety and Related Disorders: A Scoping Review of Translational and Clinical Research
Authors: Rajkumar Ravi Philip
Published: December 2022

Anxiety disorders are among the most common mental disorders worldwide and often respond incompletely to existing treatments. Selenium, a micronutrient that is a component of several biologically active selenoproteins, is also involved in several aspects of brain functioning and may exert antidepressant and anxiolytic effects through multiple pathways. The current paper is a scoping review of translational, observational, and interventional evidence on the potential role of selenium and its compounds in the management of anxiety and related disorders. Evidence from animal models suggests that this approach may be promising. Though evidence from observational studies in humans is inconsistent and affected by several confounding factors, the available evidence from randomized controlled trials suggests that selenium supplementation may be beneficial in the management of certain anxiety-related conditions, such as anxiety in medically ill patients, prevention of anxiety following exposure to traumatic stress, and obsessive-compulsive disorder. This paper provides a critical evaluation of the existing evidence base, including unanswered questions that could serve as the focus of further research, and outlines the potential benefits and risks associated with the use of selenium in anxiety disorders.
Assessing the Water Conservation Function Based on the InVEST Model: Taking Poyang Lake Region as an Example
Authors: Chen Qianru , Xu Xin , Wu Manyu , Wen Jiaming , Zou Jinlang
Published: December 2022

This paper analyzes the spatiotemporal patterns, water yield and water conservation function of different land use types in Poyang Lake Region, China, during 1990–2020 by using national land use, meteorological, soil, DEM data, etc., based on the InVEST model. The results showed that: (1) Cultivated land, forestland and water area were the main land use types in Poyang Lake Region during 1990–2020. Construction land and forestland were increasing, while grassland, unused land, cultivated land and water area were decreasing. (2) The increasing construction land was mainly derived from cultivated land. Mutual transfer existed between cultivated land and forestland, as well as between cultivated land and water area. (3) With a downward–upward–downward fluctuating trend, the average annual water yield of Poyang Lake Region was 16.17 × 109 m³, and the water conservation was 53.11 × 108 m³. The average water conservation capacity was 270.98 mm. The vegetation cover area with high water conservation value was mainly concentrated in the northwest of Jiujiang City and the northeast of Poyang County. (4) The average water conservation of different land use types during 1990–2020 was ranked as follows: water area > cultivated land > forestland > construction land > grassland > unused land. The water conservation capacity was ranked as follows: water area > grassland > forestland > cultivated land > construction land > unused land.
Factores endógenos y exógenos relacionado con el rendimiento académico de los estudiantes en una universidad pública peruana
Authors: Velasquez Bernal Libia Rocio , Fretel Quiroz Nicolás Magno , Lema Rivera Fabián Fabricio , Sánchez Ramos Blas Oscar , Fuentes Ahuanari Judith Lizet , Enriquez Medina Giancarlo Remigio
Published: December 2022

El propósito de este artículo establecer la relación entre los factores endógenos - exógenos y el rendimiento académico de los estudiantes de la Carrera de enfermería de la Universidad Nacional Amazónica de Madre de Dios en Perú. Metodología, el estudio se desarrolló bajo el diseño no experimental, la población muestral estuvo conformado por 160 estudiantes de la Carrera Profesional de Enfermería de la UNAMAD. Resultados, los factores endógenos-exógenos analizados guardan una relación estadística con el rendimiento académico de los estudiantes universitarios. Se concluye que los factores endógenos-exógenos determinan el rendimiento académico, por lo que es necesario realizar acciones preventivas mediante la intervención en las variables de características modificables a través de la formación educativa, elementos como las normas de la formación educativa universitaria, así como los elementos de actitud y todo lo relacionado a la pedagogía.
Plataformas educativas virtuales y el desarrollo profesional en Instituciones Educativas de un distrito de Lima-Perú
Authors: Soto Amasifuén Luz Roxana , Sanchez Sandoval Sara Pamela , Ramos Valderrama Delma Yesenia , Colque Ricce Oscar Alfredo , Menacho Vargas Isabel
Published: December 2022

La introducción de las plataformas virtuales en la educación, han generado grandes impactos en el desarrollo profesional de los docentes, ya que se han visto en la necesidad de adquirir nuevas metodologías y estrategias de enseñanza y aprendizaje adaptadas a los recursos digitales de las plataformas virtuales. El objetivo fue determinar la influencia de las plataformas educativas virtuales en el desarrollo profesional en Instituciones educativas de un distrito de Lima-Perú. El estudio básico, cuantitativo, correlacional, diseño no experimental-transeccional. La muestra fue censal, conformada por 91 docentes. De acuerdo a los resultados, las variables tienen una correlación positiva y significativa (Rho de Spearman = 0.667, p= ,0000< ,005). Asimismo, existe una relación positiva y significativa de las dimensiones tecnológicas y educativas, con el desarrollo profesional (Rho de Spearman = 0.648 y 0.638 respectivamente), concluyendo que las plataformas virtuales tienen una incidencia sobre la actualización y formación continua de los docentes.
Uso de los entornos virtuales para el fortalecimiento del pensamiento crítico
Authors: Gutiérrez Cárdenas María Cristina , Ledesma Pérez Fernando Eli , Cadenillas Albornoz Violeta , Aybar Huamani Justiniano
Published: December 2022

La implementación de la educación virtual debido a la pandemia que originó la enfermedad del COVID-19, determinó que los docentes dieran otra mirada a su desempeño profesional de cómo conseguir el desarrollo de competencias y capacidades al igual que en las clases presenciales. El objetivo de este estudio fue determinar la influencia del uso de los entornos virtuales para el fortalecimiento del pensamiento crítico. La metodología fue de enfoque cuantitativo, con diseño cuasi experimental, porque se aplicó un programa “Haciendo uso de los entornos virtuales en el área de Ciencias Sociales”, a 29 estudiantes en el Grupo control y 29 estudiantes del Grupo experimental, Los resultaros demostraron que, en el post test el rango promedio del grupo control fue de 17.09% y en grupo experimental 41.9 %. Concluyéndose que, el uso de los entornos virtuales influye significativamente en el pensamiento crítico de los estudiantes.
O princípio da simetria e a judicialização da matéria perante o supremo tribunal federal: experiência dos estados brasileiros na execução impositiva das emendas parlamentares individuais
Authors: Dias Audic Cavalcante Mota
Published: December 2022

O Princípio da Simetria busca harmonizar ao texto constitucional a criação das emendas impositivas ligadas à destinação do orçamento público estatal, diante da obediência material da hierarquia das normas do ordenamento jurídico. Aborda-se a atuação do Legislativo e do Executivo quanto à programação orçamentária até chegar a judicialização da matéria perante o Supremo Tribunal Federal, que busca equilibrar a atuação dos dois primeiros. Para subsidiar essa análise, foram consultados os portais eletrônicos das assembleias legislativas de todos os Estados brasileiros, bem como foi feita vasta pesquisa à jurisprudência do Supremo Tribunal Federal.
Avaliação de exposições museais: interações de turistas/visitantes com as exposições do Museu forte do presépio e do Museu de Arte Sacra, Belém, PA
Authors: Campos Raul Ivan Raiol de , Silva Lucas Oliveira da , Assis Giselle Castro de , Costa Isabel Monteiro da
Published: December 2022

As instituições museológicas transformaram sua perspectiva comunicativa, organizacional e avaliativa ao longo do tempo, atribuindo diretrizes voltadas ao público. Cientes disto, a avaliação de exposições se tornou uma importante ferramenta para identificar como sucede a interação do público no contexto das exposições. Portanto, este estudo teve como o objetivo avaliar a interação dos turistas/visitantes no Museu do Forte do Presépio (MFP) e no Museu de Arte Sacra (MAS), localizados no Centro Histórico de Belém – PA. A metodologia adotada se constitui de pesquisa bibliográfica, pesquisa documental e pesquisa de campo através de observação direta, utilizando o método Timing and Tracking de Yallowitz e Bronnekant (2009) e uso de formulário. Utilizou-se dados quantitativos relacionados aos tempos médios, número de paradas e indicadores de interação, que foram relacionados a conceitos qualitativos como Holding Power and Attracting Power (GOINS; GRIFFEHAGEN, 1957), e fadiga museal (ROBINSON, 1928) para avaliação das exposições. Constatou-se que na exposição permanente do MAS a média de paradas foi abaixo da metade do número mínimo a ser considerado em cada área da exposição, denotando um Holding Power regular. No MFP essa média de paradas foi acima do número mínimo, demonstrando um Holding Power bom. Quanto às interações dos turistas/visitantes com as exposições, em ambos os museus houve razoabilidade de Holding Power and Attracting Power. Conclui-se que a pesquisa com o Timing and Tracking contribuiu com dados essenciais para interação dos turistas/visitantes com exposições, e que o MAS e o MFP podem utilizar esses dados para fazer uma avaliação somativa a fim de melhorar a permanência e a interação dos visitantes com as areas onde essa interação não foi efetiva.
Impaired NK cell cytotoxicity in multiple myeloma caused by the homozygous A91V polymorphism in the perforin gene: a case report
Authors: Souza Bruna Maria Bereta de , Silva Marcos Vinícius da , Oliveira Leonardo Rodrigues de , Rodrigues-Júnior Virmondes , Vito Fernanda Bernadelli de , Moraes-Souza Hélio
Published: December 2022

We describe a 58-year-old man diagnosed with IgG/Kappa multiple myeloma (International Staging System III) treated for eight years with polychemotherapy (VAD schee) and autologous peripheral hematopoietic stem cell transplantation. The patient studied was homozygous C272T polymorphism (PRF1272T/T) by analysis of perforin gene by direct sequencing. This SNP is considered pathogenic and leads to the substitution of the amino acid alanine for valine in codon 91 of the perforin protein. The cytotoxic lymphocytes (CLs) of the patient and of the healthy wild homozygous individual were evaluated for their cytotoxic capacity. Our results show that PRF1272T/T effector cells had significantly reduced ability to induce specific lysis of K562 cells. The NK cells of the patient had three times less intracellular perforin than observed in the wild-type individual. The gene expression of PRF1 and FAS did not differ between the individuals, however the expression of GZMB was approximately 2.5 times higher in the patient. It was also observed that the T-BET expression was approximately 1.7-fold higher and IFN-γ expression was 4.5-fold higher in the PRF1272T/T patient. In conclusion, functional analysis of the CLs of the patient revealed a significant decrease in their cytolytic capacity as well as the amount of perforin present in NK cell granules.
Efeitos colaterais da liraglutida em pessoas não diabéticas: uma revisão integrativa da literatura
Authors: Oliveira Alessandra Fernandes Machado de , Silva Glauciane Carvalho , Barros Neuza Biguinati de
Published: December 2022

Este estudo objetivou evidenciar os efeitos colaterais da Liraglutida em pessoas não diabéticas, bem como relacionar o medicamento como coadjuvante na redução da obesidade através da perda de peso. Trata-se de uma revisão integrativa da literatura, qualitativa, realizada nas bases de dados da Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Literatura Internacional em Ciências da Saúde (PUBMED), na Biblioteca Eletrônica Científica Online (Scielo) e Biblioteca Virtual em Saúde (BVS). Estas plataformas de pesquisas possibilitou a busca por estudos publicados no cenário nacional e internacional, a partir da inclusão de artigos científicos disponíveis na íntegra, em livre acesso, publicados no período entre 2016 a 2020, nos idiomas português, inglês e espanhol, bem como aqueles que, após leitura do título e resumo, abordem aspectos relacionados à temática do estudo. Foram encontrados 65 artigos nas bases de dados, excluídos 43 após a aplicação dos critérios de exclusão, selecionados 22 artigos para serem lidos na íntegra e, ao final, 9 estudos foram incluídos para serem analisados a fim de subsidiar a revisão de literatura. Pode-se verificar em todas as publicações consultadas que a Liraglutida tem uma atividade clínica importante e os efeitos colaterais manejáveis. Sendo, assim, pode ser considerada como uma alternativa terapêutica importante, que promove a perda de peso em pacientes com ou sem diabetes, reduzindo o risco de hipoglicemia e, consequentemente, proporcionando considerável melhora na qualidade de vida dos pacientes.
Dimensional database to support water resources decisions
Authors: Tercini João Rafael Bergamaschi , Junior Arisvaldo Vieira Mello
Published: December 2022

This paper aims to demonstrate that the dimensional database model has great potential for use in water resources due to its generalization in the input and output of data and facilitates the aggregation of data for information generation. In addition, the proposed model was applied to PostgreSQL software, which is a powerful and free database engine, as it does not generate license costs for its implementation and can be even implemented in small server environments, the model is capable of performing complex queries on huge databases (billions of data) with very fast response times, reaching speeds in excess of 300,000 processed data per second. As a consequence of being generic, high performing and its low cost, so, the same methodology was applied to the monitoring module of the PCJ Basin Decision Support System (SSDPCJ), which has the function of disseminating data from the telemetry monitoring stations and it can be replicated for other cases that need to store and disseminate information on water resources.
“Os reflexos da COVID -19 na saúde mental dos trabalhadores da enfermagem” Uma revisão integrativa de literatura
Authors: Santos Rafael de Carvalho dos , Silva Barbara Taís Costa , Oliveira Damires Nascimento de
Published: December 2022

A Covid-19, causada pelo coronavírus, é uma enfermidade altamente transmissível que desencadeia, de nível leve a grave em humanos, infecções respiratórias. Em 2020, foi decretada pandemia por conta da Covid-19, a qual, mesmo diante das ações de prevenção impostas pela Organização Mundial da Saúde (OMS) à população e do esquema vacinal surgido em 2021, gerou considerável número de casos e de óbitos, o que revolucionou não só a rotina nas instituições de saúde, mas impactou os enfermeiros, sendo os profissionais responsáveis pelos primeiros contatos e cuidados com os pacientes com suspeitas e vítimas da Covid-19. Nesse contexto, o presente trabalho, pautado na pesquisa bibliográfica, uma revisão integrativa de literatura construída com materiais científicos publicados de 2020 a 2022, tem como motivador o seguinte problema: quais danos a Covid-19 causa à saúde mental dos enfermeiros? Obteve-se, como resultado, que tamanho protagonismo dos enfermeiros frente à Covid-19 causa ansiedade, desânimo, estresse, medo e tristeza nos referidos profissionais. Concluiu-se, assim, que como consequência de tais sentimentos, lidar constantemente com a Covid-19 pode causar para os enfermeiros desde insônia até crises de ansiedade, depressão e transtorno de pânico.
Amêndoas de cacau (Theobroma cacao L.) submetidas a diferentes temperaturas e tempos de secagem no norte brasileiro
Authors: Araujo Myrella Katlhen da Cunha de , Silva Ramon Rene de Cristo , Silva Magnun Antonio Penariol da , Antunes Arlindo Modesto
Published: December 2022

Muitos agricultores da região amazônica utilizam a secagem natural, processo oneroso e que compromete a qualidade do produto. Portanto, o objetivo da presente pesquisa foi verificar as melhores condições de secagem artificial das sementes de cacau, em função de diferentes tempos (6, 12 e 18 horas) e temperaturas (30°, 45° e 55°C) a fim de obter amêndoas de melhor qualidade. Ainda, conhecer a energia necessária para execução dos diferentes métodos de secagem, considerando a potência, potência específica energética, quebra de peso e tempo de utilização do protótipo secador. O estudo foi realizado no laboratório da Universidade Federal Rural da Amazônia no Campus de Tomé- Açu/PA, com sementes obtidas na região. A secagem das sementes foi executada com protótipo secador considerando as temperaturas de (30°, 45° e 55°C), com uso de um termômetro eletrônico, tempos de secagem (6, 12 e 18 horas) e fluxo de ar de 45°. Além disso, utilizado o parâmetro teor de água nas sementes ideal a 8%. Por fim, verificada a energia e os custos para secagem das amêndoas. Logo, com tarifa de energia no município de Tomé-Açu/PA por 0,67 centavos, o custo de energia obtido foi de R$ 2,96; 5,92 e 8,88, respectivamente. A secagem artificial que obteve valores próximos a 8% foi (55°C/18 h), com média de 10,96% de água nas amêndoas. Mas outras alternativas podem ser utilizadas ao alterar temperatura e/ou fluxo de ar. Assim, o consumo específico de energia para (55°C/18h) foi de 7,2 %. Ademais, os dados coletados foram importantes para melhoria de condições pós-colheita do cacau.
YESEVÎLİK ŞEYHLERİNDEN SULTAN HUBBİ KISSASININ KAZAKİSTAN NÜSHASI
Authors: SHADKAM ZUBAİDA , SULTANBEK KUTLUGJON
Published: December 2022

Works written in Eastern Turkic in Central Asia are of great importance in the field of Islamic Turkic Literature. Some of these works were written in the type of doctrine and some of them were written in the type of legend. Hagiographies have been the subject of many researchers, especially in the fields of language, literature, theology and history, both in terms of language and content. The ṣūfī-poet Hodja Aḥmad al-Yasawī (d. 562/1166), who was the founder of the Yasawī tariqa (order), had an important place in the spread of Islam among the Central Asian Turks, who deeply affected the religious-mystical life of the society. He spread Islam in the Turkestan region with his educative and instructive poems in the style of wisdom, which he said in a way that the people and his followers could understand. By followers, the Yasawī order spread to Khorasan, Azerbaijan and Anatolia from the southwest of Turkestan through the Kipchak dervishes, first starting from the Transoxiana area. In Central Asia, there are many legends about Hodja Aḥmad al-Yasawī’s legends and miracles, and his followers and dervishes also have miracles. Although there are some differences between them, these religious, mystical characters still preserve themselves in the life and belief of the people of the region. One of them is the legend of Sultan Hubbi (Ḥubbī), the son of Süleyman Bakırgani, known as Ḥakīm Ātā, one of the first successors of Hodja Aḥmad al-Yasawī. The legends of Sultan Hubbi is mentioned in the studies of researchers such as N. Tosun, Ö. Kaya and Kazakhstani researchers S. Kondybai, F. Kamalova. Our research is based on the Chagatai manuscript of the Sultan Hubbi legend found in Kazakhstan. The life, miracles of Sultan Hubbi, the 3rd son of Ḥakīm Ātā Süleyman Bakırgani, who played an important role in the spread of the Yasawī order in Mangistau and according to some researchers, in Turkmensahra, with the underground mosque, valley and well of Sultan Hubbi in Mangistau. It is aimed to give information about the common rumours. In this direction, the methods of compiling, examining, translation and evaluation of scientific studies and articles published on the subject will be used. Our aim is to introduce the Almaty/Kazakhstan with the copy of the Kıssa-i Sultan Hubbi manuscript, which is one of the historical texts written in Eastern Turkic (Chagatai), which was not reached and unknown for a long time during the Soviet Union period, with the thought that it could contribute to the research of the Turkic world. Keywords: Hagiographies, Yasawīsm, Ḥakīm Ātā, Sultan Hubbi, Kazakhstan.
YAŞAYAN BEKTAŞİLİK BAĞLAMINDA AKSARAYLI ÂŞIK MEHMET ÇİL’DE HACI BEKTAŞ ALGISI
Authors: PEKER SELÇUK , JABLE ERGİN
Published: December 2022

Various beliefs and practices of the Bektashi order, which was founded by the followers of Hacı Bektaş-i Veli, one of the leaders of Turkish mysticism, are still alive in some Turkmen settlements in Anatolia. Gaziemir village of Aksaray, where Bektashism continues to exist as a way of life, is one of them. The village is close to Hacı Bektaş-i district of Nevşehir, to Yūnus Emre Tomb, and to the village and tomb of Taptuk (Emre) in Ortakoy district of Aksaray, which accounts for the vitality of the belief and practice regarding the three great mystics in the village. Gaziemir village is 100 kilometres to the Hacı Bektaş-i Veli Complex, 87 kilometres to the Yūnus Emre Tomb, and 50 kilometres to the Taptuk Emre Tomb. The residents of Gaziemir village visit the Hacı Bektaş-i Veli Tomb in their daily lives for various reasons such as having a child and making vows, and regularly participate in the annual Hacı Bektaş-i Veli Commemoration Festival. Âşık Mehmet Çil, who was born into the Alevi-Bektashi culture in the village of Gaziemir, served regularly as baba (a religious title granted to the helper of the spiritual leader dede in Alevism) for a long time, and represented dede, who came to the village once a year. Mehmet Çil, who spent most of his life in his village dealing with animal husbandry and farming, apart from some short leaves for military service and business purposes, is one of the strongest representatives of Bektashism, regarding the culture he was born into and the duty he assumed in this culture. This study aimed to make evaluations about Bektashism in the example of Gaziemir village and to determine the effect of the concrete existence of Hacı Bektaş-i Veli Complex on the continuity of living Bektashism. The method used in this study is field research based on natural observation, and text-centred analyses were carried out on Mehmet Çil’s poems related to the subject. The result of the study revealed that the cultural vitality in the village and the concrete existence of Hacı Bektaş-i Veli Complex contributed significantly to the continuity of the belief. Keywords: Hacı Bektaş-i Veli, Alevism-Bektashism, Aksaray, Âşık Tradition, Mehmet Çil.
KASAP ESNAFINA DAİR FARSÇA YAZILAN ÜÇ FÜTÜVVETNÂME
Authors: DOĞAN TURAY ESRA , BAYLAN ZİVAR HÜSEYNLİ
Published: December 2022

Among the Persian futuwwatnāmes, which started with the Ṣafavid period and are described as Persian Cevânmerd, there are also epistles belonging to butchers. The writing of these works began in the Great Khorasan basin during the Seljuk period. These works are considered as the main sources of the 13th century Anatolian Akhism. In Persian futuwwatnāmes, this profession is attributed to Prophet Ibrahim. The master of the profession Hazrat (Excellency) Ali were counted, and as the hero of the profession, Reyli Cevânmerd-i Kassâb, based on Hazrat Ali and considered one of the close men of Muhammed Hanafiyya (d.81), was accepted. The first of the Futuwwatnāme written in Persian belongs to Molla Hüseyin Vaizi Kâşifi Sabzevari (d.1504), who is the owner of the famous work called Ravzatü'şŞüheda. and in the section titled " Fasl der Beyân-i Gabze-i Kârd, Sâtur, Kârdmâl ve Tir ". The other treatise, named Futuwwatnāme-i Kassâb, is in the manuscript magazine numbered 8898 in the Iranian Parliament Library. It is stated that it belongs to Molla Muhammed Bagir Majlis (d.1699) and was written during the Ṣafavid period. The third and last treatise is among the manuscripts of the Iranian Sipahsalar Madrasa Library, with the name of Der Beyan-i Kar-i Kassâban ve Sellahân. Its author is unknown. The inscription record is 1879. In these three works, similar issues related to butchery were discussed and the basic principles of the profession were determined. Detailed information is given about the butchers' chefs. The secret of the sacrifice of Prophet Ibrahim's son Ismail has been emphasized, the masters of the profession have been introduced, and the verses and hadiths of the profession have been mentioned. The decency and manners of the butcher shopkeepers were listed, and the moral rules of butchers were dictated in the form of questions and answers. This article draws attention to the similarities between the introduction and translation of the Persian Futuwwatnāmes on the butchery profession and the futuwwatnāmes in two languages. He emphasizes that these works are the continuation of each other and that they should be read and known together. Keywords: Persian Futuwwatnāmes, Butcher Craftsman, History of Akhi Order, Muhammed Baghir, Molla Huseyin Kashifî, Safavids.
PÎR-İ PEHLEVÂNÂN MAHMÛD-I PÎRYÂR-I VELÎ, HAYATI, MENKIBELERİ VE ESERLERİ
Authors: MUKADDEM ALİ RIZA
Published: December 2022

Evliya Çelebi, in the description of wrestlers in his famous Seyahatname, mentions that their master is “Hazrat-i Mahmūd-i Pīryār-i Valī”, although he fails to provide further details, mentioning only that he is “Hazrat-i Hamza’s kamar-basteh.” Even he wants to mention where her grave is, but probably he could not reach this information so leaves the place blank in the relevant line. There is a lack of significant information about this character in Turkish modern studies, even sometimes it is possible to find wrong information, however, there is much written about him both in historical and hagiographic sources and in studies conducted outside of Turkey. In the present article, the life, legendary sagas and works of Pahlavan Mahmūd-i Pīryār-i/Pūryā-yi Valī, who lived in the 13th-14th centuries and is still known as the master of traditional wrestling athletes, have discussed and the current discussion on these issues have evaluated. In the results, it was determined that Pahlavan Mahmūd was born in the Khiva of Khwārazm in the middle of the 13th century and died in the same city in the first quarter of the 14th century. In addition, it has been revealed that the claims that his grave was found in the city of Khoy in Azerbaijan are unfounded. In the article, the nickname "Pīryār-i/Pūryā-yi Valī", which is an integral part of the name of Pahlavan Mahmūd and is often used instead of his name, has been examined in detail and based on the oldest sources, and different views on this subject have been discussed. While some sources emphasize that this name is a nickname, some sources insist on the thesis that in reality this name was the name of Pahlavan Mahmūd’s father and was used as the name and nickname of his son Mahmūd over time. This issue still remains a mystery! Keywords: Mahmūd-i Pīryār-i Valī, Pūryā-ı Valī, Wrestling Lodges, Wrestling, Malamatiyya, Sufism, Persian Literature, Khwārazm.
HZ. ALİ MUSHAFLARI: NİSPET AÇISINDAN İNCELENMESİ
Authors: CANKURT FATİH
Published: December 2022

"The gate of science" Hazrat Ali is one of the people who have an important place in the history of Islam in many ways. The name of Hazrat Ali, who was from the family of the Prophet and was one of the leading scholars and scribes of revelation, has been included in many discussions. In addition to the fact that he should have the priority in the office of the head of state (caliphate), he has even been the subject of false claims that prophecy is his right, especially given by Shia sources. One of the current issues about Hazrat Ali throughout history is the mushafs attributed to him. It is generally accepted that Ali wrote a mushaf that belonged to him. As a result of this acceptance, there are mushafs claimed to have been written by Hazrat Ali in many Islamic cities today. While some of these are complete mushafs, others contain some parts of the Qur’ān as a piece of mushaf. Whether these mushafs belong to Hazrat Ali is one of the problems that are of interest to Muslims and therefore need to be investigated. In accordance with the assumption that it is a mushaf belonging to Hazrat Ali, introductory information about this mushaf is given in some sources. In this study, which is prepared on the basis of the information given about Hazrat Ali's mushaf, TMSK 2, TMSK 29 and TİEM 458 mushafs, along with the San'a copy attributed to Hazrat Ali, are examined in terms of attribution to him. In the study, first of all, technical and introductory information about the mushafs, which are important because each of them was written in early periods, is given. In the second part, it has been determined what kind of information is given about the mushaf written by Hazrat Ali in the sources and which features are included. In the last part, considering these features, four mushafs were examined and it was tried to determine whether the mushafs comply with the mentioned features. On this occasion, the issue of attributing the mushafs to Hazrat Ali has been tried to be clarified and the question marks on the subject have been resolved. As the details are stated in the content of the study, as a result of this research, it has been concluded that there is no harmony between these historically important mushafs and the features mentioned about the mushaf written by Hazrat Ali, and it is not possible for these mushafs to belong to Hazrat Ali. Keywords: The Qur’ān, Qur’ān Recitation, Mushaf, Hazrat Ali, Shia.
MALTEPE BAŞIBÜYÜK KÖYÜ DAVER BABA/KERİME NİNE TEKKESİ
Authors: MADEN FAHRİ , KAYA SERKAN , ÖZYOL ERDAL , GÜREL HASAN BASRİ
Published: December 2022

The Khorasan erens, the gazi dervishes and the Alp erens played important colonial roles in the Turkification and Islamization of Anatolia. Among the struggles of the Ottoman Principality in Byzantium, these gazi dervishes settled in the Kartal-Goztepe region and took on the role of spectators. Daver Baba Lodge was established and operated in Basıbuyuk village in Kartal-Maltepe region. There is no information about lodge’s activities at that time. It is said that Daver Baba built this unit in the 18th century. In 1826, during the closure and demolition of the Istanbul lodge on the banning of Bektashi, the destruction of the Daver Baba Lodge was also discussed. Daver Baba Lodge, which had been destroyed and closed for a long time, was revived by Kerime Nine in the second half of the 19th century. The 1871 tombstone, which is missing today, states that he was a saint. There is no information about lodge’s activities after its reopening. It is known that he is one of the supporters of the National Struggle. In 1925, due to the closure of all tekke, zāwiyah and tombs, Daver Baba Lodge’s activities came to an end, and the tekke property passed to the waqf (religious endowment) administration. Meanwhile, the lodge land, which was in the possession of Fatma Melahat Güllüzade, was put up for sale in 1933 with an advertisement published in the newspaper Aksam. Sükrü Gulluoglu, who bought the lodge properties, tried to protect the remaining relics from the lodge. In the meantime, the headship of the dervish lodge was conferred on Ekrem Halifebaba from Adana. However, the lodge building, which resisted the destruction of time until recent years, disappeared completely in the early 1990s. Today, the remains of the Ayazma, the fountain and the foundation walls of the Daver Baba Lodge are left behind. In addition, there are no traces left from the present, and the old tombstones have been lost. There is only a newly inscribed marble tombstone indicating that Daver Baba, Kerime Hatun and the martyrs were found there. We do not have archive records related to Daver Baba Lodge. The information available is more based on the observations made by Reshat Ekrem Kocu in the 1960s. In this study, the history of Daver Baba Lodge is considered within the framework of the researches carried out so far with the information given by Kocu and the archive records related to Basıbuyuk village where the tekke was established. Keywords: Istanbul, Maltepe, Basıbuyuk, Bektashism, Daver Baba, Kerime Nine, Adanali Ekrem Halifebaba.
TUNCELİ EMEK GAZETESİNE KONU OLAN ALEVİLİK VE HABERLERİN ELEŞTİREL SÖYLEM ANALİZİ
Authors: ŞENOL ŞENGÜL
Published: December 2022

This study aims to analyse the articles and news on Alevism in Tunceli Emek Newspaper. In the study, news and articles about Alevism published in Tunceli Emek Newspaper between 1 January 2020 and 31 December 2020 were classified. The news items were analysed in terms of the subject and distribution of the news, the type of expression, the language of individuals and institutions, Alevi hearths (ocak), the discourses of the mothers and grandfathers (murshid, pīr and guide) who are the representatives of the hearths, and the representation of beliefs in the local press and the importance of these representations in terms of keeping cultural memory alive. It was analysed whether these news items reflect Alevism's cultural heritage and tradition. The extent to which these news items contribute to democracy and social development was also analysed. As a result of the study, the survival of Alevism in Tunceli, its transmission to new generations, the place of rituals and its importance in social communication and the transformations it has undergone today were emphasised. The articles about Alevism and news about Alevis in Tunceli Emek Newspaper, as well as the extent to which Alevi values are represented, were evaluated adopting Teun A. Van Dijk's critical discourse analysis method. Keywords: Alevism, Tunceli, Alevi Belief, Tunceli Emek Newspaper, Hearths.
AHİLİKTE DEĞERLER EĞİTİMİ VE BİR DEĞER OLARAK NASİHAT
Authors: SAYAN YUNUS EMRE
Published: December 2022

Akhism, highly influential in Islamic and Anatolian societies between 13th and 19th centuries is a professional, commercial, economic, cultural, social, moral and educational organization whose influence in this process exceeds the boundaries of time and space. It consists of highly moral and well-behaved people, each of its members interacting with each other, providing both material and spiritual guidance to its members, and aiming at the perfect human being. On the basis of its acceptance and strong influence for ages the role of its construction with a spirit and understanding inspired by Islamic sources is very great. It is very important scientifically in terms of dealing with Akhism in a way that sheds light on the present, to make sense of it by examining it, evaluate it, and to benefit from the results of a successful experience in the past. Considering that education is an activity of introducing ideal cultural elements to future generations, the introduction of institutions that affect the culture of society in history to today's people is also among the duties of education. In Akhism, educational values, both verbal and behavioral, have been inherited from the past to the present within the framework of the master-assistant master relationship. The aim of this study is to determine the prominent values in Akhism and to reveal the importance of advice value. In this context, the values in the Akhi organization and the value of “advice”, which stands out from these values, were investigated. At the same time, the role of the concept of advice in adding value to individuals and societies has been tried to be determined, although its value has weakened today. The study has been designed with a qualitative research design and the main Islamic sources have been examined in accordance with the document analysis method in the research. Based on the richness of meaning of the concept of advice, the aspect of advice that educates a person, guides, shapes life and makes it valuable and how it builds a lifestyle has been examined. In this study, according to the 5N+ 2K (What, why, where, how, when and who, to whom) technique, the use of advice and teaching methods in the Akhism have been tried to be determined. It is assessed that the results obtained from the richness of meaning of the advice, which has been determined to have an important place in theA khism, will shed light on today's educators and values education. Keywords: Religious Education, Akhism, Values, Advice, Advice in Akhism.
KUR’AN’IN KAVRAMLARA KATTIĞI MANA DERİNLİĞİ ÜZERİNE: ‘FETÂ’ ÖRNEĞİ
Authors: ÇONKOR BURHAN
Published: December 2022

The Qur'ān, in the concepts it uses and the provisions it brings, taking into account the norms of the society in which it was revealed, conveyed its messages to humanity through them. By interfering with the events that developed in a period of twenty-three years, the understanding of life envisaged by Islam was gradually placed in the minds. The Qur'ān was downloaded in Arabic and used the concepts of the Arab society to which it was addressed. However, the Qur'ān uses some concepts, especially the words, Allah, Rab, etc. are used to place in minds the equivalent of religion, not the life style of the polytheistic society. Therefore, some concepts have undergone a process of change with the use of the Qur'ān and these meanings have settled in the minds over time. The concept of fetā, which expresses the young character with certain characteristics in the Arabs of the Jahiliyya period, has also changed with the use of the Qur'ān, negative features of the pre-Islamic period are excluded from this concept. Due to the change that the concept of fetā went through and its effect on social life, it also took on an institutional structure under the name of futuwwa in the post-prophecy period. In short, there are important differences between pre-Islamic and post-Islamic meanings and the messages that are intended to be given when fetā is said. In addition, the Qur'ān has added a new dimension to the concept by using this concept about distinguished people such as prophets. In our study, the concept of fetā has been examined in detail and its usage in pre-Islamic and Qur'ān has been compared. Based on the character traits of the fetā expressions in the Qur'ān and the personalities mentioned by these expressions, the change and breadth in the concept have been tried to be determined. In addition, it is understood that the use of this concept in the Qur'ān was in the second half of the Makkan period and in the time period close to the Hijra. In this direction, with the use of the related concept, it was emphasized which messages were given through the addressees of that day. Since it expresses youth in the most general sense, the concept of fetā was mentioned in the studies carried out in line with the Qur'ān and the main theme of youth, and it was also mentioned in studies on futuwwa. In our study, related studies were also used from time to time. However, in this article, in addition to the determination of the meanings of fetā and its derivatives, it has been tried to reveal the meanings meant by their use in the Qur'ān and their messages to the period in which they descended in context. We hope that our study will contribute to a better understanding of the meaning content of the related concept and the messages given by the Qur'ān by using this concept. Keywords: Qur'ān, Exegesis, Fetā, Makkī, Futuwwa.