bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFICACY OF R.O.C.S. PRO MOISTURIZING TOOTHPASTE IN PATIENTS WITH XEROSTOMIA
OF VARIOUS ETIOLOGY
Authors: Akulovich Andrey , Buzova Ekaterina , Borovskaya Alexandra , Yakunina Larisa , Matelo Svetlana
Published: January 2023

Maintaining comfort in the oral mucosa and improving quality of life in patients with xerostomia (dry mouth) is an urgent necessity both for dental specialists, who constantly find this symptom in many patients, and for manufacturers and suppliers of oral hygiene products. Patients with dry mouth in addition to symptomatic
therapy with artificial saliva, need to optimize personal oral hygiene, because changes in saliva quality or amount will inevitably lead to deterioration in the oral tissues. Therefore, the development of affordable oral hygiene products which alleviate xerostomia manifestations is of great importance in improving the quality of life of patients with dry mouth.
This study presents the results of the examination of a number of clinical properties of R.O.C.S. PRO Moisturizing toothpaste for patients with xerostomia of different severity. According to pH-metry, after the use of this paste, there is a pronounced shift in the pH of saliva to alkaline, which is explained by the presence of a buffer system contained in the paste, able to neutralize the excess acidity of the oral fluid. An increase in the
salivation volume according to sialometry over the period of application of the paste (by an average of 0.6 ml) may be due to the presence of a mint salivary stimulating flavor in the composition of the paste. The obtained positive dynamic changes in metabolic processes in the oral fluid against the background of the use of the developed paste give grounds for its broad recommendation for normalizing the state of the oral mucosa and mineral metabolism of the enamel in patients with symptoms of xerostomia
Luteinizing hormone receptor expression in lymphoma is not affected by body weight, sex, immunophenotype, or tumor stage in gonadectomized dogs
Authors: Zwida Khawla , Vedus Alyssa , Kutzler Michelle
Published: January 2023

Purpose of this investigation was to determine if luteinizing hormone receptor (LHR) expressionin canine lymphoma was affected by body weight, sex, immunophenotype (B cell, T cell) or tumor stage.Formalin-fixed, paraffin-embedded lymphoma tissue samples from spayed and neutered dogs (n = 40),representing multiple breeds and mixed breeds, were subjected to routine immunohistochemicaltechniques using a polyclonal LHR antibody. Percentage of cells positive for LHR and the stainingintensity (scored 0 - 3) were determined at 400 x magnification. Data were expressed as mean ± standarddeviation and significance was defined as p < 0.05. Differences between sex and tumor phenotype, bodyweight and tumor stage were compared. All tumor samples had cells positive for LHR. However,percentage of cells expressing LHR and its immunostaining intensity varied among individuals. Therewere no significant differences in percentage of LHR positive cells or staining intensity within sex orimmunophenotype. Additionally, there was no significant association between percentage of LHRpositive cells or staining intensity within body weight or tumor stage. We concluded that increased risk oflymphoma in spayed and neutered dogs was not related to body weight, sex, immunophenotype or tumorstage. However, it is possible that risk of lymphoma may be related to increased LHR activationfollowing gonadectomy.
YAPAY ZEKÂ ALGORİTMALARI İLE DÖNÜŞEN DENETİM ARAÇLARI ÜZERİNE BİR DEĞERLENDİRME
Authors: EFE Ahmet , TUNÇBİLEK Merve
Published: January 2023

Yapay zekâ (YZ) uygulamalarıyla birlikte gelişen yenilikçi teknolojiler nedeniyle Sayıştay ve teftiş mekanizmaları dahil olmak üzere tüm iç ve dış denetim mesleğinin bir bütün olarak bir zorluk ile karşı karşıya olduğu söylenebilir. Bu zorlukların bir kısmı yeni fırsatlarla birlikte üstesinden gelinmesi gereken engelleri ve riskleri barındırabilmektedir. Veri analitiği araç ve tekniklerini denetim otomasyon yazılımlarıyla birlikte kullanmak dahil olmak üzere iç denetimde teknolojiden yararlanmada daha etkin ve verimli bir iş yapma ihtiyacı vardır. Büyük veri zorluğundan dolayı yavaş işleyen denetim, örneklemeye dayalı denetim planlamasına dayanan denetimin maliyet ve risklerinin artması denetim görevlerini hızlandırmak için otomasyonun gerekli olduğunun birer göstergeleridirler. Bu çalışma, YZ ile birlikte gelişen riskleri ve fırsatları dengeleyecek şekilde denetim süreçleri bağlamındaki otomasyon çözümlerini incelemektedir. Genel olarak piyasada kullanılan akıllı denetim uygulamaları ve özelde ise AuditMap.ai örneği üzerinden YZ tabanlı denetim otomasyon uygulamalarının denetçinin yerine geçerek değil, aslında insan merkezli denetim planlama, programlama, yürütme, test, raporlama ve izleme süreçlerine değer katarak denetim sürecine yardımcı olunduğu ortaya konulmaktadır.
Konsep Kelestarian dari Perspektif Islam Berbanding Pendekatan Moden dalam Melestarikan Negara
Authors: Hashim Saleh , Abdullah Amalina
Published: January 2023

The emergence of sustainability ideas aims to systematically tackle economic, social and environmental challenges that affect the people’s quality of life. Economic, social and environmental systems have been adversely affected by those who solely pursue personal gain in the long run but at the expense of the wellbeing of others. The idea of sustainability, drawn from the widely known Brundtland Report, states that a combination of environmental, social and economic pillars contribute to sustainability. However, the debate on the effectiveness of the theory continues as global populations are still affected by long-standing sustainability issues, such as global warming, persistent wealth inequality, poverty and food deprivation or hunger. This paper adds to the discussion on Islamic sustainability as an avenue emphasising the soft factor (i.e. human) that encompasses the soul, mind and intelligence (‘aql) in addressing sustainability problems. This Islamic perspective deines the roles of responsible human beings with the following principles, namely: i) fairness (‘adl); ii) expertise (ihsan); iii) the highest sense of human understanding (arham); and iv) not spreading mischief and moral corruption (fasad) in rebellion to God when managing national institutions. Based on these principles, human beings may manage a country fairly, implement expert management, take care of the welfare of others and do no harm in order to maintain sustainability of the country in the future. Keywords: Sustainability, Sustainable Development, Environment
Design and Development of Hybrid Spectrum Access Technique for CR-IoT Network
Authors: Singh Sandeep
Published: January 2023

The radio spectrum is an underutilized natural resource with significant untapped potential. The rapid proliferation of Internet of Things (IoT) devices is driving a dramatic increase in radio spectrum demand. These devices can utilize cognitive radio (CR) technology to access the bandwidth left unused by licensed spectrum users, also known as primary users (PUs), to meet end users spectrum requirements efficiently. However, because PUs are given priority, CR-enabled Internet of Things (CR-IoT) devices, also known as secondary users (SU), must frequently communicate with one another in an opportunistic manner or under stringent power constraints. This can complicate CR-IoT device communication, render it unstable, and restrict its throughput. This paper proposes a hybrid spectrum access algorithm that combines underlay and interweave spectrum access methods to address this issue. When a PU is detected, under the proposed scheme, CR-IoT devices utilize underlay spectrum access. In contrast, when no PU is detected, CR-IoT devices employ interweave spectrum access. In addition, a proposed iterative algorithm permits CR-IoT devices to adapt their sensing thresholds, and sensing time based on the Signal-to-Noise ratio (SNR) received from Pus to strike a balance between achievable throughput and fairness among PUs and CR-IoT devices in extremely noisy channel. Simulation results demonstrate that the throughput for CR-IoT devices increases by 28% in proposed scheme when compared to the conventional spectrum access schemes.
El surgimiento de la inteligencia estratégica en la Argentina: enfoques doctrinarios y percepción de amenazas durante la Guerra Fría
Authors: Poczynok Iván
Published: January 2023

El artículo analiza las transformaciones que experimentó la inteligencia estratégica argentina en la segunda mitad del siglo XX. El trabajo aborda el período comprendido entre el surgimiento de los primeros elementos de inteligencia estratégica en la década de 1940 y la recuperación de la democracia en 1983. El supuesto general que orienta estas reflexiones es que, al igual que en los países centrales, el desarrollo de esta actividad en la Argentina estuvo motorizado por los debates estratégicos asociados a la transformación de las formas de la guerra y los enfrentamientos militares en la primera mitad del siglo. La doctrina de defensa nacional, aprobada en 1948, fue la principal expresión institucional de esta mirada. Sin embargo, tras el derrocamiento de Perón en 1955, esta concepción fue reemplazada progresivamente por un enfoque doctrinario que colocó al sostenimiento del orden interno en la cima de las prioridades de la inteligencia nacional. El ascenso de la doctrina de seguridad nacional, apuntalada por la confluencia de intereses entre elites político-militares domésticas y potencias extranjeras, representó un punto de inflexión en la configuración profesional de la inteligencia argentina. Por un lado, porque orientó las prioridades de inteligencia del país hacia el “frente interno”, en función de una agenda estratégica supranacional. Por el otro, porque sentó las bases de un proceso de ideologización de los organismos de inteligencia que tuvo consecuencias dramáticas no solo para la historia nacional, sino también para la preservación de los intereses estratégicos del país.
PROTOTYPE ALAT DETEKSI KEBOCORAN GAS LPG MENGGUNAKAN NODEMCU ESP8266
Authors: Kusumah Indra Maulana Yusup , Ramdhani Dede Suarna , Yusmansyah Erfizal Fikri
Published: January 2023

Keterbatasan sumber daya alam mendorong manusia untuk menggunakan bahan bakar gas. Namun, bahan bakar gas ini memiliki efek negatif, yaitu seringnya terjadi kebakaran yang disebabkan oleh ledakan gas.
Kebakaran akibat ledakan gas LPG sering terjadi di rumah warga dan sering kali tidak dapat diantisipasi dengan baik. Oleh karena itu, diperlukan sebuah alat yang dapat mendeteksi kebocoran gas sehingga ledakan yang disebabkan oleh kebocoran tersebut dapat segera diantisipasi, mencegah kebakaran agar tidak meluas.
Alat pendeteksi kebocoran gas yang akan dibuat mampu mendeteksi kebocoran dan memberikan informasi jika terjadi kebocoran gas. Alat ini menggunakan sensor MQ-2, modul WiFi ESP8266, LCD, buzzer, kipas, dan sensor api sebagai notifikasi. Alat ini dapat mendeteksi kebocoran gas dan memberikan informasi kepada pemilik, sehingga kebakaran dapat diantisipasi sedini mungkin. Informasi yang dihasilkan oleh alat ini berupa bunyi alarm dan pesan yang dikirimkan melalui Telegram kepada pemilik saat kebocoran gas terdeteksi, sehingga kebakaran akibat ledakan gas dapat ditangani dengan cepat dan efektif.
Faktor Yang Mempengaruhi Produktifitas Kerja Pada Badan Usaha Milik Desa
Authors: Setiawan Muhammad Hengki
Published: January 2023

Tujuan Artikel: Penelitian ini bertujuan untuk mengetahui faktor yang memengaruhi produktivitas di BUMDes, Desa Panggung Lestari, Desa Panggungharjo, Kecamatan Sewon, Kabupaten Bantul.Metodologi: Metode penelitian ini adalah accidental sampling.Hasil: Hasil penelitian ini bisa digunakan untuk mengukur kriteria, penilaian keadilan kerja, motivasi produktivitas kerja
Deskripsi Review Kinerja Karyawan Pada Perusahaan Di Masa Pandemi Covid 19
Authors: Wai Florentina Ina
Published: January 2023

Tujuan–Pandemi covid 19 berpengaruh signifikan terhadap kinerja karyawan. Kinerja karyawan dipengaruhi oleh faktor internal seperti motivasi kerja, budaya kerja dan kompensasi. Situasi pandemi sebagai faktor eksternal juga berpengaruh terhadap kinerja, budaya kerja, motivasi kerja, kompensasi dan kesehatan mental karyawan. Artikel ini akan mendeskripsikan hubungan dan pengaruh antara kinerja karyawan dengan faktor- faktor tersebut. Desain/Metodologi/Pendekatan–Artikel ini menggunakan metode deskriptif review. Deskripsi ini menggunakan data dalam bentuk artikel ilmiah yang diambil dari perpustakaan digital seperti jurnal, ebooks, dan karya referensi lainnya secara daring. Kajian ini bersumber dari open knowledge maps dan academia.edu dengan kata kunci “kinerja karyawandan pandemi covid 19”. Kajian ini menemukan bahwa kinerja karyawan sangat dipengaruhi oleh pandemi covid 19. Faktor-faktor seperti budaya kerja, motivasi kerja, kompensasi dan kesehatan mental karyawan mengalami perubahan akibat pandemi covid 19. Hal ini berpengaruh kuat terhadap kinerja karyawan. Semakin tinggi budaya kerja, motivasi kerja, kompensasi dan kesehatan mental semakin tinggi pula kinerja karyawan. Semakin tinggi kemampuan teknis karyawan dan semakin baik fasilitas yang disediakan perusahaan berkaitan dengan covid 19 semakin tinggi pula kinerja karyawan di masa pandemi covid 19.Kata Kunci: Pandemi Covid 19, Kinerja, Budaya Kerja, Motivasi Kerja, Kompensasi, Kesehatan Mental
Pengaruh Harapan Kinerja terhadap Penilaian Kinerja sebagai Umpan Balik Karyawan melalui Teknologi Turnover Intention
Authors: Firmansyah Thoufiq Galih
Published: January 2023

Tujuan–Penelitian bertujuan untuk mengetahui pengaruh harapan kinerja karyawan terhadap penilaian kinerja yang dimediasi oleh teknologi turnover intention. Dengan mengetahui besarannya pengaruh dari variabel yang diteliti, diharapkan dapat memberikan rekomendasi yang baik untuk memberikan strategi dalam peningkatan penilaian kinerja karyawan. Metode–Penelitian ini menggunakan metode Accidental Sampling. Penelitian ini merupakan penelitian kuantitatif,dengan sampel dalam penelitian ini 72 karyawan. Teknik pengambilan data dilakukan dengan menggunakan kuesioner. Hasil–Penelitian ini menunjukkan bahwa terdapat pengaruh positif dan signifikan harapan kinerja karyawan terhadap turnover intention, harapan kinerja karyawan berpengaruh positif terhadap penilaian kinerja jaryawan, dan turnover intention berpengaruh positif signifikan terhadap penilaian kinerja karyawan. Kata kunci: Penilaian Kinerja Karyawan; Harapan Kinerja Karyawan; Teknologi Turnover Intention
Mapping Management of Innovation and Leadership in the Sustainability of an Organization; Bibliometric Analysis 2020-2022
Authors: Rahmawan Zudi , Destri Wulandari , Parjiyati  , Wulansari Rika , Yuhara Rr. Tisie , Muhamed Ariff
Published: January 2023

Purpose - ArticleThis paper presents and discusses the impact of an innovation implemented by leadership on the sustainability of an organization which is taken from mapping through biblometric analysis. In order to compete with other organizations, organizations must have innovation and be innovative in looking for new ideas or breakthroughs. In fact, there have been many studies related to management innovation. But here we are interested in examining how much researchers who conduct innovation management research directly related to leadership use bibliometric analysis through VOSViewer.

Design/methodology/approach - We use a bibliometric method and review related to Innovation and Leadership management. We obtained the data source for the bibliometrics through the Scopus database.

Findings and Discussion – The results of research with mapping using the keyword "Management Innovation" show two clusters. In the first cluster there are 2 interrelated elements, namely study and innovation which are closely related to the innovation itself. In the second cluster there is only Development related to innovation. Innovation Connectivity between clusters can be seen through the nodes. The bigger the node, the higher the frequency of occurrence.

Conclusion - The study can be concluded that Innovation Management and Leadership are very closely related. It has been proven that in the last 2 years there have also been many studies highlighting management innovation but most of them have researched management innovation in the education sector. In addition, Innovation Management also ranks first on the vosviuwers search page. The citations used for research also reach thousands in the article. Articles on innovation management also reach hundreds of articles published annually by various studies.
Organizational Changes; Bibliometric Analysis For 2016-2022
Authors: Noviana Tri , Sulistyawati Eni , Sagala Pinondang br , Romiyati
Published: January 2023

Purpose - This study aims to determine the changes that are taking place and to analyze Organization Change publication trends regarding the number of articles, the number of citations to a journal, the relevance of affiliation, the most authors, publishers and network clusters.This research is the first step to look at existing research and find research themes related to organizational change

Design/methodology/approach - This research uses the Bibliometric analysis method. The data was obtained through searching the Google Scholar (GS) database with the word Organization Change in the category Article title, Abstract, Keywords. Approximately 153 articles were obtained in the initial results with 569 citations (56.9 citations/year)

Findings and Discussion – The search results obtained 129 articles, the citation data also changed, with 367 citations and 52.43 citations/year, during the 2016-2022 period. From the results, 129 articles were refined and the citation data also changed to 367 citations and 52.43 citations each year. The results of the study show that the most cited authors are a. J Suwaryo HKK, and its most relevant affiliate is the University of Indonesia. b. Aslami and Rahman are the most authors, ejournal.unsrat.ac.id is the largest publisher c. words that often appear are organization change, change, organization, organizational change, and study.

Conclusion - Bibliometric mapping supports the scientific explanation between probability theory and evidence. Research on Organizational Change can be developed more broadly on themes that appear few and have not been widely included in research in the last seven years. Therefore, this research is expected to be a reference for further research
Measuring water flow rate for a fire hose using a wireless sensor network for smart fire fighting :
Authors: Brown Christopher U , Tam Wai Cheong , Vogl Gregory W
Published: January 2023

A wireless sensor network was created to measure water-flow rate in a fire hose. An integrated electronic piezoelectric (IEPE) accelerometer was chosen as the sensor to measure the flow rate based on the vibrations generated by water flowing through a fire hose. The improved flow apparatus, including the accelerometer, was lightweight, small, and easily attached and removed to any location along the fire hose, not obstructing the water s flow path. The wireless flow apparatus was used with realistic firefighting hose conditions (i.e., holding the hose nozzle, nozzle motion during simulated fire suppression, simulated hose dragging) to evaluate the upgraded apparatus function and determine the influence of the hose motion, accelerometer location, and nozzle spray on the dominant-frequency metric. While more research is needed, such as enhancing the robustness of the dominant frequency metric, the preliminary research and this update shows the potential of a smart fire hose for improved situational awareness during fire suppression.
Acolher o transcendente no hospital: concepções de voluntários que promovem apoio religioso-espiritual
Authors: Bernardi Franzini Maria Gabriela , Scorsolini-Comin Fabio , Fukumasu da Cunha Vivian
Published: January 2023

Este estudo objetivou conhecer as concepções de voluntários que prestam apoio religioso-espiritual em um Hospital Geral acerca das relações entre religiosidade/espiritualidade (R/E) e os processos de saúde-doença. Foram entrevistados 15 voluntários, a maioria cristã, com média de idade de 57,06 anose de 8,06 anos de atuação. Esses participantes compreendem que a dimensão da R/E possui relações diretas com os desfechos positivos em saúde. Esses desfechos não necessariamente correspondem à cura, mas à possibilidade de acolhimento em um momento de forte mobilização emocional, bem como de construção de inteligibilidades sobre a morte, o morrer e o luto. Apesar do serviço retratado ser sustentado na diversidade religiosa, foram observadas ações que são produzidas por e voltadas para, em sua maioria, adeptos de religiões cristãs. Recomenda-se que as religiões nãohegemônicas também possam estar efetivamente representadas, permitindo o acolhimento apacientes que professam diferentes religiões/religiosidades/espiritualidades1.
Espiritualidade/Religiosidade nos Cuidados Paliativos:
Authors: France Turan Salvador Sileide , Gomes Esperandio Mary Rute
Published: January 2023

A Organização Mundial de Saúde estabelece que o cuidado às pessoas que enfrentam doenças fatais, ou seja, em cuidados paliativos (CP) deve incluir a dimensão espiritual. Este estudo teve como objetivo evidenciar a percepção das equipes multidisciplinares sobre questões espirituais/religiosas na assistência paliativa. O método de pesquisa foi de natureza mista, transversal, caracterizado como descritivo e exploratório. A coleta de dados se deu através de um questionário semiestruturado, formado por 39 questões fechadas e uma aberta. Colaboraram no estudo 25 profissionais de equipes de CP. 94% consideram que a religiosidade coopera no tratamento e 76% percebem que pacientes gostariam de trazer as questões religiosas para o tratamento. Estes profissionais destacam a necessidade de receber formação para abordar as questões de E/R (96%) e entendem como importante a atuação de um cuidador espiritual na equipe para prover a assistência espiritual em caráter profissional. Esta lacuna na formação de profissionais da Saúde, aliada à necessidade de assistência espiritual de pessoas e familiares em CP, convoca a teologia a desenvolver uma reflexão teórica e prática que contribua com propostas consistentes de cuidado espiritual para aplicação no contexto dos Cuidados Paliativos.
Abordagens Narrativas em Espiritualidade e Saúde
Authors: Esperandio Mary Rute Gomes , Fernandes Marcio , Souza Waldir
Published: January 2023

Não se aplica.
Escrita infantil: junção e tradição discursiva
Authors: Lopes-Damasio Lúcia Regiane
Published: January 2023

Resultado de pesquisas realizadas na Universidade Estadual Paulista (Unesp), da graduação à pós-graduação, esta obra apresenta, de forma leve e objetiva, um modo de olhar para a escrita infantil, capaz demonstrar a riqueza com que essa escrita se apresenta a quem se dispõe a vê-la sem as lentes da gramática projetada para a escrita padrão. Para reconhecer as relações entre mecanismos de junção e tradições de textos, a abordagem teórico-metodológica aqui propõe a conjugação de aspectos linguísticos e discursivos. Nesse espaço, os mecanismos de junção deixam de ser tomados exclusivamente como categorias linguísticas e ganham estatuto de rastros da circulação do sujeito por sua imagem da escrita. Esses rastros permitem o reconhecimento, no material escrito, da movimentação do sujeito para a construção dos sentidos na textualização. Nesta obra, a riqueza com que a escrita infantil se mostra ao leitor deixará clara a importância da investigação proposta, não unicamente para a compreensão do caráter heterogêneo da/dessa escrita, mas também para futuras proposições que favoreçam o seu ensino.
The environmental fate of metals from zinc and lead mining area in surface water (Przemsza River, southern Poland)
Authors: Pierri Dorota , Rutkowski Marcin
Published: January 2023

The chemical composition of surface waters of the Przemsza River flowing through Upper Silesia (in southern Poland) is strongly affected by Zn and Pb ore, and less by Carboniferous hard coal deposits. The chemical type of surface water is Ca-HCO3. In the waters, three groups of metals and metalloids were found that directly interfere with the mineralization of the deposit. Although genetically related to the same deposit, each group exhibits a different fate in the environment. A typical deposit association is Pb-Zn-Ag-As-Sb-Hg. The first group of metals in surface waters is consistent with the typical association of the ore Zn-Pb-Cd-(Tl), the second includes Ag-Sb-Hg, and the third includes the additives in the zinc and lead ore Co-Ni-Mo-Mn:[(Ca↔Na)+(HCO3↔Cl)]+[(Zn-Pb-Cd-(Tl))+(Ag-Sb-Hg)+Co-Ni-Mo-Mn)].Depending on the pH-Eh conditions, metals and metalloids precipitate out of the solution or sorb on solid particles. The concentrations of individual groups of metals are interdependent but show different environmental fates along the river course. The natural process of the enrichment of surface waters with Zn-Pb-Cd-(Tl) is by water circulation in a rock matrix naturally rich in the metals and draining groundwaters by the river. Under oxidizing and slightly alkaline conditions, Ag-Sb-Hg incorporated into the soluted chemical compounds, may, when the physicochemical parameters of the waters change, be adsorbed and/or precipitated. The presence and ratio of concentrations of Co-Ni-Mo-Mn with respect to zinc are almost identical, differing only in concentration.
Transport parameters of selected neonicotinoids in different aquifer materials using batch sorption tests
Authors: Pietrzak Damian , Kania Jarosław , Kmiecik Ewa
Published: January 2023

Contamination of surface and groundwater by neonicotinoids is a global problem and requires comprehensive action by individual countries in order to identify in detail the processes affecting the transport of these pesticides, their properties, and their harmfulness to the environment. The aim of this study was to assess the transport (expressed by sorption parameters) of selected neonicotinoids in the aquatic environment, using batch tests. Tests were carried out for acetamiprid individually and a mixture of five neonicotinoids (acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam), for three different aquifer materials and quartz sand. Based on the obtained values of the sorption parameters, the greatest sorption of neonicotinoids was observed on soil with the highest content of organic matter and clay minerals content, while no sorption of these pesticides was observed on quartz sand. In addition, it was noticed that individual neonicotinoids undergo sorption to a different degree — thiacloprid was the most sorbed (R-value in the range 3.13–26.03), while thiamethoxam was the least (R-value in the range 1.89–8.41).
Preliminary studies of photolysis and TiO2-montomorillonite-immobilised photocatalysis processes for the degradation of organic pollutants in water treatment
Authors: Pamuła Justyna , Karnas Magdalena , Styszko Katarzyna
Published: January 2023

Organic compounds are the most diverse group of contaminants. The largest anthropogenic source of these contaminants in water is municipal and industrial wastewater. One of the indicators of surface water pollution is biological oxygen demand (BOD). Purifying water from organic micropollutants is a serious challenge and requires the development of newer and more effective methods. The removal of such contaminants is most effective only in advanced oxidation processes (AOP), which include UV photolysis and photocatalysis. The presented results are from preliminary research to evaluate the effectiveness of water treatment by ultraviolet (UV) photolysis and photocatalysis. Treatment efficiency was evaluated on the basis of changes in the BOD index before and after the advanced oxidation process of raw water. The values of the BOD5 index determined in accordance with PN-EN 25813:1997. The exposure time of the samples was a maximum of 60 minutes. The tested material was water samples taken from the Rudawa River, which is one of the drinking water sources for Krakow. The initial BOD5 value (expressed as concentration of O2) for all samples was about 8 mg/L but it has decreased to over 2 mg/L due to AOP processes. This means that after an hour, more than 75% of organic compounds present in the raw water were removed. For photocatalysis (TiO2-MMT), the exposure time of the samples was a maximum of 35 minutes. Water samples taken from the Rudawa River were also used as test material. The initial BOD5 value for all samples was about 9 mg/L but it has decreased to about 4 mg/L due to the photocatalysis process. This means that after 35 minutes, 55% of the organic compounds present in the raw water were removed.
A new agglutinated foraminiferal species (Arenoturrispirillina waskowskae sp. nov.) from the Danian of Contessa, Italy
Authors: Hikmahtiar Syouma , Kaminski Michael A.
Published: January 2023

This paper describes a new Paleogene deep-water agglutinated foraminifera from the Contessa Highway Section, Umbria-Marche Basin, Italy. The new species Arenoturrispirillina waskowskae is characterised by its predominently high trochospiral coiling, which distinguishes it from the genus Glomospira. The new species is also found in the Polish Carpathians.
Emotional Appetite Questionnaire: psychometric properties in Brazilian adult samples before and after the COVID-19 pandemic onset
Authors: Martins Bianca G. , Vanini Nadine V. , Campos Lucas A. , Campos Juliana ADB
Published: January 2023

Background

Appetite represents a desire of a person to eat specific food in order to reach satisfaction and pleasure states. This desire may be associated with the experience of negative or positive emotions (emotional appetite). Emotional appetite can influence eating behavior, and its investigation is relevant to avoid possible damage to health resulting from a disordered eating.

Objectives

To adapt the Emotional Appetite Questionnaire (EMAQ) to the Portuguese language; to assess the validity and reliability of the data; and to assess emotional appetite in three samples of adults collected before and after the outbreak of the COVID-19 pandemic.

Methods

This is a cross-sectional study with non-probabilistic convenience sampling. The Portuguese version of the EMAQ was presented after translation, back-translation, and content analysis. Two studies were conducted, the first before and the second after the pandemic onset. Three samples were formed (2019: Sample 1 (age = 19.7 ± 1.5 years) n = 323; 2020: Sample 2 (age = 21.3 ± 1.8 years) n = 1,011; and Sample 3 (age = 28.9 ± 3.1 years) n = 909). An exploratory strategy with parallel analysis was performed. The analyses were conducted in FACTOR and R (lavaan and semTools packages) software. After determining the best-fit model for the data, emotional appetite was examined considering decrease, non-alteration, and increase in appetite in the face of positive and negative emotions/situations. The profile of emotional appetite was determined using a circumplex model.

Results

The two-factor model described by the valence of emotions/situations fitted the samples (Comparative Fit Indexminimum-maximum = 0.95–0.98; Tucker-Lewis Index = 0.94–0.98; Root Mean Square Error of Approximation = 0.03–0.08; αord = 0.78–0.88). Increases in appetite were more frequent for positive emotions/situations (52.0–57.5%), and both decreases (35.4–44.5%) and increases (50.0–56.2%) in appetite were observed for negative emotions/situations. Emotions with negative valence and activation were more relevant to appetite reduction, while a significant increase in appetite was observed with anxiety (negative valence and positive activation).

Conclusion

Different emotions and situations may influence appetite in people, and such an investigation may be useful in preparing eating protocols.
Next-generation sequencing shows the genomic features of ovarian clear cell cancer and compares the genetic architectures of high-grade serous ovarian cancer and clear cell carcinoma in ovarian and endometrial tissues
Authors: Gan Meifu , Tai Zaixian , Yu Yijian , Zhang Chao , Xu Juan
Published: January 2023

Ovarian clear cell carcinoma (OCCC) is a special histological type of epithelial ovarian cancer (EOC) that is not derived from epithelial cells of the ovarian or fallopian tube as the most common type of ovarian cancer, high-grade serous ovarian carcinoma (HGSOC), but is closely related to endometriosis and similar to endometrial clear cell carcinoma (ECCC) at morphologic and phenotypic features. However, limited data was shown in OCCC genomic features and compared with that in OCCC, HGSOC and ECCC. Herein, we utilized next-generation sequencing analysis of a panel of 1,021 genes to profile the mutational alterations in 34 OCCC and compared them to those from HGSOC (402 cases) and ECCC (30 cases). In result, the ARID1A and PIK3CA are high-frequency mutations of OCCC. Clonal architectures showed that all the mutations of genes occur in the later stage in the OCCC progress, whereas KRAS mutation is the earlier event compared with mutation of ARID1A or PIK3CA, which usually occurs in a group of ARID1A or PIK3CA mutations. The mutation frequency of main driver genes is similar between OCCC and ECCC, while TP53 is the main mutation in HGSOC and ECCC. Shared mutational signatures between OCCC and ECCC tissues with commonly observed a C>T change indicated a common carcinogens-exposed between these two carcinomas, but HGSOC and ECCC have common and distinct mutational signatures across cohorts respectively. In addition, we identified some novel CNV gains in NF1, ASXL1, TCF7L2, CREBBP and LRP1B and loss in ATM, FANCM, RB1 and FLT in OCCC. Our study offered a new perspective for OCCC tumorigenesis from two organs, the ovary and uterus, at genomic architectures and revealed novel CNV events for helping to provide theoretical support for OCCC treatment.
Detection of fungicide resistance to fludioxonil and tebuconazole in Fusarium pseudograminearum, the causal agent of Fusarium crown rot in wheat
Authors: Zhang Na , Xu Yiying , Zhang Qi , Zhao Le , Zhu Yanan , Wu Yanhui , Li Zhen , Yang Wenxiang
Published: January 2023

Fusarium crown rot (FCR) on wheat is a soil-borne disease that affects the yield and quality of the produce. In 2020, 297 Fusarium pseudograminearum isolates were isolated from diseased FCR wheat samples from eight regional areas across Hebei Province in China. Baseline sensitivity of F. pseudograminearum to fludioxonil (0.0613 ± 0.0347 μg/mL) and tebuconazole (0.2328 ± 0.0840 μg/mL) were constructed based on the in vitro tests of 71 and 83 isolates, respectively. The resistance index analysis showed no resistance isolate to fludioxonil but two low-resistance isolates to tebuconazole in 2020. There was an increased frequency of resistant isolates from 2021 to 2022 based on the baseline sensitivity for tebuconazole. There was no cross-resistance between fludioxonil and tebuconazole. This study provides a significant theoretical and practical basis for monitoring the resistance of F. pseudograminearum to fungicides, especially the control of FCR.
Comprehensive profile and contrastive analysis of circular RNA expression in cervical squamous carcinoma and adenocarcinoma
Authors: Luo Hongxue , Zhu Yi , Wang Jiaqi , Wang Yue , Wei Lihui
Published: January 2023

Background

Numerous studies have shown circular RNA (circRNA) dysregulation is associated with the pathogenesis of cervical cancer,particularly in individual carcinoma variants. The aim of this study is to investigate and contrastively analyze the expression pattern of circRNAs in cervical squamous carcinoma and adenocarcinoma mediated by human papillomavirus type 16 (HPV-16).

Methods

The expression of circRNAs in cervical squamous carcinoma (SCC), adenocarcinoma (ADC) and adenosquamous carcinoma (ASC) tissues, together with the adjacent normal tissues (ANT), was profiled by high-throughput RNA sequencing (RNA-seq). Bioinformatics analysis and quantitative real time polymerase chain reaction (qRT-PCR) validation of the sequencing data were performed. A network of circRNA-miRNA (microRNA)-mRNA was then constructed according to predicted targets and function of candidate circRNAs.

Results

A total of 11,685 annotated circRNAs were identified in six cervical samples. There were 42 up-regulated and 98 down-regulated circRNAs. 215 circRNAs were up-regulated in SCC but down-regulated circRNAs in ADC, while 50 circRNAs displayed the opposite trend. Function enrichment analysis based on different expressions of circRNAs found that the most enriched pathway in all the three pathologic variants of cervical cancer was the “ubiquitin mediated proteolysis” pathway. Eight key candidate circRNAs derived from this pathway were further validated, and we noticed that several target miRNAs of candidate circRNAs could target the source genes. Based on this we constructed a related competing endogenous RNA (ceRNA) network.

Conclusion

Through a comprehensive interpretation of differentially expressed circRNAs in different pathologic variants of cervical cancer, this study provides new insights into the process of tumor differentiation mediated by HPV. Our results may help to complement the molecular typing and stem cell theory of cervical cancer.
Development of Android-Based Learning as Interactive Learning Media in Reaction Rate Material on XI Class SMA Student
Authors: Silaban Ramlan , Alexander Irving Josafat , Panggabean Freddy Tua Musa , Simanjuntak Hendra , Nababan Julianshe Lydia , Sitorus Marham
Published: January 2023

This aims of this study are to: (1) find out whether android-based interactive learning media that developed have met the feasibility standards based on the android-based integrated BSNP, (2) find out whether student learning outcomes taught using android-based interactive learning media that have been developed higher than the Minimum Completeness Criteria (KKM) score on the reaction rate material. This research is a Research and Development with the ADDIE (Analysis, Design, Development, Implementation and Evaluation) model which was carried out in the odd semester of the 2021/2022 academic year at SMAN 12 Medan. At the implementation stage, a one-group pre-test post-test design was used, with sampling using a cluster random sampling technique consisting of one XI science class at SMAN 12 Medan. The results of the validation of the android-based media obtained for the feasibility of the contents is 3.75; display feasibility is 3.83; language feasibility is 4, and graphic feasibility is 3.83. Overall, android-based learning media obtained a feasibility level of 3.85, with a very feasible category. Furthermore, android-based learning media on the reaction rate material is implemented in the learning process. The KKM scores and the students' average post-test scores were 78 and 85.6, respectively. The data obtained were analyzed using the right-hand t-test. The result of data analysis is that tcount is in the significant area, tcount > ttable = 4.146 > 1.711. So that Ha is accepted and H0 is rejected, it can be concluded that the learning outcomes of students who are taught using Android-based interactive learning media are higher than the KKM value.
Cartografía de áreas cubiertas por Acacia dealbata en imágenes multiespectrales invernales y estivales captadas por dron en la comarca de Verín (Ourense, Galicia, España)
Authors: Vázquez de la Cueva Antonio , Aulló Maestro Isabel , Montes Pita Fernando
Published: January 2023

Acacia dealbata es una planta invasora que se expande favorecida por perturbaciones. El objetivo de este trabajo ha sido cartografiar las áreas ocupadas por A. dealbata mediante el análisis de imágenes multiespectrales y RGB y comparar el comportamiento de las imágenes obtenidas durante la floración invernal y las obtenidas en verano. Las imágenes fueron adquiridas mediante un dron DJI Matrice 210 en tres lugares localizados en la comarca de Verín. La identificación de los píxeles ocupados por la Acacia se llevó a cabo mediante la aplicación basada en ajustes de máxima entropía MaxEnt. La verdad terreno (puntos de presencia conocida) se basó en la fotointerpretación de ortomosaicos RGB invernales mientras que las variables predictoras fueron las reflectancias en las bandas del espectro visible e infrarrojo y un índice de vegetación. El Área Bajo la Curva (AUC) en los análisis ROC (Receiver Operating Characteristic) de los modelos MaxEnt para las tres zonas de estudio presentó valores entre 0.80 y 0.86 para las imágenes invernales y entre 0.83 y 0.90 para las estivales, indicando una alta especificidad y sensibilidad. Estos valores, y también los derivados de las matrices de confusión, ponen de manifiesto la aplicabilidad del procedimiento para el seguimiento de la distribución de flora invasora como la Acacia. Los resultados muestran el mejor comportamiento de las imágenes estivales frente a las invernales en la cartografía detallada de áreas ocupadas por A. dealbata.
Developing a discipline-specific corpus and high-frequency word list for science and engineering students in graduate school
Authors: Uehara Suwako , Haraki Hibiya , McLean Stuart
Published: January 2023

Japanese graduate school students in the field of science and engineering need to read academic research in their second language (L2), and such tasks can be challenging. Studies showed a strong (0.78) correlation between vocabulary size and reading comprehension (McLean et al., 2020), and providing high-frequency word lists could enhance comprehension. In this work-in-progress, 1.35 million tokens of professor-recommended reading materials were used to investigate a method to create a vocabulary list that would benefit science majors in graduate school, the procedures to create a corpus and a high-frequency word list efficiently, and the steps required to create a cleaner corpus. This paper outlines a systematic literature-informed method that includes input from professors in the field, the combined use of tailored script in MATLAB and AntCont (Anthony, 2022) generated corpus and high-frequency words efficiently, and repeated comparison of original PDFs and the matching text files, then adding MATLAB script to deal with specific issues created by a cleaner text. This proposed method can be applied in other contexts to enhance the generation of high-frequency word lists.
A commentary on four papers in the second language vocabulary learning strand for the JALT Vocabulary SIG
Authors: Yamashita Junko
Published: January 2023

In this commentary, the following four papers have been reviewed and discussed: Vocabulary Learning Outside of the Classroom: Institutional Use of a Spaced Repetition Vocabulary Learning App (Mueller & Hays, 2022), Developing a Discipline-Specific Corpus and High-Frequency Word List for Science and Engineering Students in the Graduate School (Uehara et al., 2022), Rasch-based Instrument Validations for an Augmented Reality Vocabulary Acquisition Experiment (Dabrowski, 2022), and Orthographic Processing of Proper Names: A Proposal to Investigate the Orthographic Cue for Second Language Readers (Klassen, 2022).
Trends in Outpatient Visits and Hospital and Intensive Care Unit Admissions of Adults With COVID-19 in an Integrated US Health Care System, March 2020 to January 2022
Authors: Myers Laura C. , Ng Kevin , Plimier Colleen , Daly Kathleen A. , Kipnis Patricia , Liu Vincent X.
Published: January 2023

This cohort study of patients at a single integrated health system examines trends in COVID-19–related treatment location and mortality.
Rechallenge After Oxaliplatin-Induced Hypersensitivity Reactions
Authors: Rassy Elie , Le Roy Florence , Smolenschi Cristina , Valéry Marine , Boige Valérie , Ducreux Michel , Boilève Alice
Published: January 2023

This cohort study assesses the outcome of oxaliplatin desensitization for patients with gastrointestinal cancers who experienced hypersensitivity reactions after oxaliplatin infusion.
Association of Polygenic Risk Scores for Hearing Difficulty in Older Adults With Hearing Loss in Mid-Childhood and Midlife
Authors: Wang Jing , Lange Katherine , Sung Valerie , Morgan Angela , Saffery Richard , Wake Melissa
Published: January 2023

Importance

Although more than 200 genes have been associated with monogenic congenital hearing loss, the polygenic contribution to hearing decline across the life course remains largely unknown.

Objective

To examine the association of polygenic risk scores (PRSs) for self-reported hearing difficulty among adults (40-69 years) with measured hearing and speech reception abilities in mid-childhood and early midlife.

Design, Setting, and Participants

This was a population-based cross-sectional study nested within the Longitudinal Study of Australian Children that included 1608 children and 1642 adults. Pure tone audiometry, speech reception threshold against noise, and genetic data were evaluated. Linear and logistic regressions of PRSs were conducted for hearing outcomes. Study analysis was performed from March 1 to 31, 2022.

Main Outcomes and Measures

Genotypes were generated from saliva or blood using global single-nucleotide polymorphisms array and PRSs derived from published genome-wide association studies of self-reported hearing difficulty (PRS1) and hearing aid use (PRS2). Hearing outcomes were continuous using the high Fletcher index (mean hearing threshold, 1, 2, and 4 kHz) and speech reception threshold (SRT); and dichotomized for bilateral hearing loss of more than 15 dB HL and abnormal SRT.

Results

Included in the study were 1608 children (mean [SD] age, 11.5 [0.5] years; 812 [50.5%] male children; 1365 [84.9%] European and 243[15.1%] non-European) and 1642 adults (mean [SD] age, 43.7 [5.1] years; 1442 [87.8%] female adults; 1430 [87.1%] European and 212 [12.9%] non-European individuals). In adults, both PRS1 and PRS2 were associated with hearing thresholds. For each SD increment in PRS1 and PRS2, hearing thresholds were 0.4 (95% CI, 0-0.8) decibel hearing level (dB HL) and 0.9 (95% CI, 0.5-1.2) dB HL higher on the high Fletcher index, respectively. Each SD increment in PRS increased the odds of adult hearing loss of more than 15 dB HL by 10% to 30% (OR for PRS1, 1.1; 95% CI, 1.0-1.3; OR for PRS2, 1.3; 95% CI, 1.1-1.5). Similar but attenuated patterns were noted in children (OR for PRS1, 1.1; 95% CI, 0.8-1.2; OR for PRS2, 1.2; 95% CI, 1.0-1.5). Both PRSs showed minimal evidence of associations with speech reception thresholds or abnormal SRT in children or adults.

Conclusions and Relevance

This population-based cross-sectional study of PRSs for self-reported hearing difficulty among adults found an association with hearing ability in mid-childhood. This adds to the evidence that age-related hearing loss begins as early as the first decade of life and that polygenic inheritance may play a role together with other environmental risk factors.