bluuebunny/crossref_metadata_2025 huggingface dataset:
FLUOROQUINOLONE-BASED SHORT-COURSE CHEMOTHERAPY OF PULMONARY TB IN CHILDREN FROM NIDI OF MULTIDRUG RESISTANT TB: POTENTIALS FOR USE
Authors:   Central TB Research Institute, Moscow, Russia,N.I. Pirogov Russian National Research Medical University, Moscow, Russia, Gubkina M.F , Khokhlova Yu.Yu. ,   Central TB Research Institute, Moscow, Russia, Petrakova I.Yu. ,   Central TB Research Institute, Moscow, Russia, Sterlikova S.S. ,   Central TB Research Institute, Moscow, Russia, Yukhimenko N.V. ,   Central TB Research Institute, Moscow, Russia
Published: December 2023

Objective: to justify the potentials for use of fluoroquinolone-based short-course chemotherapy for the treatment of pulmonary TB in children from nidi of multi-drug resistant TB. Materials and methods. We carried out a cohort prospective study of 18 patients aged 2–5 years with newly diagnosed pulmonary TB with history of exposure to multidrug resistant TB in 2018–2020. The criteria for inclusion were as follows: local or small TB processes without bacterioexcretion, potential to form the initial combination containing at least four TB drugs including fluoroquinolones, use of TB drugs consideringpreserved drug susceptibility in the infection source. The criteria for exclusion: presence of diseases requiring long-term immunosuppressive therapy, administration of bedaquiline at any point of treatment. We used individualized chemotherapy regimens: 4 drugs in the intensive phase and 3 drugs in the continuation phase. The treatment course was 9–12 months. Results. All the patients completed treatment with effective outcomes, no relapse was detected one year later. Intoxication symptoms were removed after 3 months, positive X-ray dynamics was observed after 3 and 6 months in 66.7% of patients. Conclusion. We proved the effectiveness of fluoroquinolone-based short-course chemotherapy regimens in children with local or small forms of TB and history of exposure to multidrug resistant TB. The criteria for the total treatment duration (9 or 12 months) were the duration of the intensive phase and the duration of fluoroquinolone administration. If the intensive phase of treatment was less than 3 months or the administration of fluoroquinolones was less than 6 months, the total treatment duration was prolonged to 12 months.
THE EFFECTIVENESS OF ARTIFICIAL PNEUMOPERITONEUM BEFORE AND AFTER PNEUMONECTOMY IN PATIENTS WITH ADVANCED DESTRUCTIVE PULMONARY TB
Authors:   Central TB Research Institute, Moscow, Russia, Salikhov B.U. , Krasnikova E.V. ,   Central TB Research Institute, Moscow, Russia, Lepekha L.N. ,   Central TB Research Institute, Moscow, Russia, Tarasov R.V. ,   Central TB Research Institute, Moscow, Russia,   Moscow Medical University “Reaviz”, Moscow, Russia, Chitorelidze G.V. ,   Central TB Research Institute, Moscow, Russia, Donchenko D.V. ,   Central TB Research Institute, Moscow, Russia, Bagirov M.A. ,   Central TB Research Institute, Moscow, Russia,   Russian Medical Academy of Postgraduate Education, Moscow, Russia
Published: December 2023

Aim: to evaluate the effectiveness of artificial pneumoperitoneum (APP) in the pre-operative and post-operative period in patients, who underwent pneumonectomy due to advanced destructive pulmonary TB. Materials and methods. We studied 104 patients, who underwent pneumonectomy with anterior mediastinal plasty (AMP) due to advanceddestructive pulmonary TB. The patients were divided into two groups. The main group consisted of 34 patients enrolled prospectively, who underwent APP before and after pneumonectomy with AMP. The comparison group consisted of 70 patients enrolled retrospectively, who did not undergo APP before and after pneumonectomy with AMP. Treatment effectiveness was estimated based on the parameters of the early course and late course (after 2 months) of post-operative period and dynamic chest X-ray signs. We also performed morphological and bacteriological studies of resection samples to estimate TB activity and bacterioexcretion massivity. Results. The effectiveness of APP for prevention of mediastinal lung hernias (MLH) was 93.3%. The studies of resection samples from the main group patients revealed decreased incidence of lymphohematogenic or bronchogenic dissemination, as well as more pronounced organization of granulomas and small foci as compared to resection samples from the controls. The comparison of key spirometry parameters in the groups did not reveal significant differences. Conclusion. The use of APP before and after pneumonectomy with AMP is a safe and highly effective method for prevention of MLH. It also contributes to stabilization of TB process in the remaining lung.
MIDDLE EAR TUBERCULOSIS
Authors:   Astrakhan State Medical University, Astrakhan, Russia, Streltsova E.N. , Bainakova Yu.R. ,   Astrakhan State Medical University, Astrakhan, Russia, Myshlyakova I.G. ,   Regional Clinical TB Dispensary, Astrakhan, Russia
Published: December 2023

The article describes a clinical case of middle ear tuberculosis without affection of the lungs or other organs. The absence of prior TB or exposure to TB is rare and atypical for this clinical form of TB.
Pelatihan Perakitan Komputer Untuk Meningkatkan Keterampilan Bagi Santri di Ponpes Al Mutmainnah
Authors: Ardhana Valian Yoga Pudya , Mulyodiputro M. Dermawan
Published: December 2023

The role of computers in everyday life is increasingly important. Computers can be used as a tool for running a business and doing all office, industrial, construction and lecture tasks. Computers have many varieties of both types and types, ranging from standard types, medium to high-tech computers. With the large role of computers at this time, the Al Mutmainnah Islamic Boarding School in the Kediri sub-district, West Lombok Regency, collaborated with the community service team at Qamarul Huda Badaruddin University to provide computer assembly training to students. This training is intended to equip students to have special skills in computer assembly and later it is hoped that they will be able to open their own jobs from this computer assembly training. The material provided can be received, digested, and understood by the participants well. The large number of participants in proportion to the number of devotees made this training more conducive. The activity went smoothly, on time and as expected and the students were able to communicate well with the speakers and other students.
Meningkatkan Pemahaman dan Budaya Literasi Terhadap Informasi Publik: Pengaruh UU ITE dan Pemanfaatan Teknologi Informasi dalam Pendidikan
Authors: Hermanto Odang
Published: December 2023

In this digital era, it is crucial for society to possess a profound understanding of information literacy and the wise use of social media. This journal discusses how comprehension and cultural literacy regarding public information can be enhanced, considering the limitations imposed by the Information and Electronic Transactions Law (UU ITE) on social media. Furthermore, this journal also explores how information technology can be harnessed as a means to enhance education. In the current digital age, public information has become more accessible through social media and other online platforms. However, the presence of the Information and Electronic Transactions Law (UU ITE) gives rise to constraints on the use of social media. This paper deliberates efforts to amplify comprehension and cultural literacy concerning public information and examines how the utilization of information technology can support education in facing the constraints regulated by the UU ITE. With a focus on social media usage and the implications of the UU ITE, as well as the utilization of information technology in education, this research aims to identify endeavors to augment the understanding of accurate and relevant information amidst the complexity of digital information
Edukasi Peran Orang Tua Terhadap Anak Dalam Penggunaan Media Sosial Sebagai Bentuk Persiapan Menghadapi Revolusi Industri 5.0
Authors: Herman Sukrina , Badriyyah Azhar
Published: December 2023

Era of technological advancement, technical ideas can start from simple concepts and transform into large businesses that impact millions of people. This is different from the past when ideas only emerged in laboratories. Technological progress has infiltrated many aspects of human life, including education, sales, shopping, entertainment, and even media consumption. An illustrative example is the use of smartphones to access social networks, which can sometimes be challenging to control, especially among children today. The Community Service Program (PKM) aims to provide understanding, awareness, and education on the crucial role of parents in guiding children's use of social networks as preparation for the Industry 5.0 revolution. This initiative involves collaboration with village officials, community leaders, and digital experts. Using methods such as lectures, discussions, and Q&A sessions, the workshop utilizes presentations and video demonstrations to highlight AI threats. After the material presentation, interaction and prize distribution commend participation in the PKM. The research results indicate enthusiastic responses from the Kertajaya Village community, reflecting their willingness to actively monitor smartphone and social media usage in the future, especially concerning children. This reflects a promising step toward increased awareness and public education about the impact of technological advancements.
Sosialisasi Child Grooming : Cyber Crime yang Mengintai Anak-Anak di Era Digital
Authors: Hardianti Fitri , Kumorotomo Wahyudi , Setianto Widodo Agus
Published: December 2023

Indonesia is in second place in cyber crime cases in the world. According to Komnas Perempuan’s record, in 2022, online gender-based violence (KBGO) cases occupy the highest position in complains to Komnas Perempuan in the public domain, covering 69% of the total cases. Riau, as one of the provinces in Indonesia, is also not immune to cases of sexual crimes in cyber space.  A number of online media reported that Riau experienced an increase in cases of violence against children and women in 2021, this was an increase of 40 cases compared to 2020 .  One of the reasons is the lack of parental knowledge of sexual crimes. In addition, the public’s view of sex is still considered very taboo. With current technological developments, it is analogous to an “open gate” that everything can be easily accessed and all forms of cyber crime will easily stalk children, including child grooming. The purpose of this community service is to socialize to the community regarding the dangers of child grooming and provid solutions on how to overcome them. This community service will involve one partner, namely the Raudathul Athfal Alkausar school, Sialang Sakti Village, Dayun District, Siak Regency. The solution offered in this service is to provide counseling related to one type of sexual crime in the digital era called Grooming to both teachers and parents. One of the successes in this service can be seen from the understanding obtained by the teachers and also the guardians of the students. The output targets of this service will later be published in the nationally accredited journal and local electronic mass media.
Pelatihan Pemasaran Digital Dalam Upaya Meningkatkan Usaha UMKM Pada Makaroni Nampol By MTH Foods
Authors: Fitriani Rina , Widiyawati Widiyawati , Chodijah Siti , Satria Satria , Sulistyowati HS. , Hami Aidah
Published: December 2023

The era of Industrial Revolution 4.0 and Society 5.0 in various walks of life is also felt by MSMEs who are expected to be able to adopt digital in product marketing, both through social media and various marketplaces. It is also important for an entrepreneur to manage relationships with his customers, both loyal customers and acquiring new customers. Customer data generated from interactions on social media and marketplaces can be used for promotions and minimizing costs. There is a gap between technological developments and digital skills in society, especially Makaroni Nampol by MTH Foods as an MSME that has just started using technological devices, which is the background for service and supporting the Tri Dharma Lecturers. Service method with Training and Mentoring which aims to provide an entrepreneurial mindset, improve the skills of business actors more deeply, such as: online NIB (Business Permit Number) registration, Google My Business, creating accounts on social media, product photography techniques, copywriting and creating BMC ( Business Model Canvas). As a result of this activity, the owner of the Makaroni Nampol by MTH Foods business was very enthusiastic about participating in the training and mentoring, asked a lot of questions in an effort to improve digital marketing, and after attending the training he was able to create a business account on the social media WA, Instagram and TikTok.
Faktor Faktor Yang Mempengaruhi Pengelolaan Keuangan Mahasiswa Akuntansi
Authors: Indah Nur , Narung Merliana Solangia , Jonas Belasinta Nova , Abrantes Rivany Fabiola Nahak , Lian Yohanes Pemandi
Published: December 2023

Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh literasi keuangan, pengaruh financial self efficacy dan pengaruh kualitas pembelajaran keuangan terhadap mahasiswa dalam mengelola keuangan. Teori yang digunakan dalam penelitian ini adalah Theory of Planned Behavior. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian kuantitatif dengan metode desktriptif. Sampel dalam penelitian ini adalah mahasiswa semester 3 pada Program Studi Akuntansi Unwira. Teknik pemilihan sampel yang digunakan yaitu teknik purposive sampling Analisis yang digunakan dalam penelitian yaitu analisis deskriptif. Hasil menunjukan bahwa Semakin tinggi kualitas pembelajaran yang dipahami mahasiswa maka semakin baik pula perencanaan anggaran keuangan yang di susun mahasiswa tersebut.
Formulation d’un émulgel à base d’un mélange d’huile essentielle d’Ocimum gratissimum L. (Lamiaceae) et du gel d’Aloe vera (L.) Burm. F. (Asphodelaceae) contre les acnés vulgaires
Authors: Ganfon Habib , Assanhou Gabin , Dazoundo Steeve , Ohin Brice , Baba-Moussa Farid
Published: December 2023

Introduction : L’acné due à une production excessive de sébum associée ou non à une prolifération bactérienne est habituellement traitée avec des topiques. L’Aloe vera (AV) et l’Ocimum gratissimum (OG) sont deux plantes traditionnellement utilisées dans le traitement de l’acné. Ainsi, notre étude a consisté en des essais de formulation et d’évaluation de l’efficacité antibactérienne d’un émulgel combinant ces deux plantes.

Méthodologie : Les essais ont été faits à partir du gel d’AV à la proportion de 10% et 20% respectivement associée à l’huile essentielle (HE) d’OG à 5% et 10% permettant d’élaborer un émulgel à base de l’HE gélifiée avec du carbomère 980 à 1%. La stabilité de nos formulations a été évaluée par des tests pharmaco-techniques que sont la détermination des caractères organoleptiques, l’examen microscopique, le test de stérilité et la mesure de quelques paramètres physico-chimiques (conductivité, pH, viscosité et aptitude à l’étalement) et l’activité antibactérienne a été déterminée sur les germes du genre Staphylococcus.

Résultats : La formule à 10% d’AV et 5% d’OG a été retenue au regard de sa plus grande stabilité. Au plan organoleptique, elle présentait un aspect homogène, une uniformité de couleur, une bonne consistance et une odeur caractéristique de l’OG. Sa conductivité évaluée à 1935µS/cm a confirmé le sens de l’émulsion Huile/Eau. Quant à la viscosité, elle était de 344400 mPa.s suggérant une bonne aptitude de l’émulgel à l’étalement. Enfin le pH (7,38) indiquait une bonne compatibilité avec celui de la peau, confirmée par les tests d’irritabilité sur le lapin albinos (Indice d’irritabilité IIP ˂ 0.5). L’activité antibactérienne sur les germes du genre Staphylococcus méticillino-résistante a montré une bonne sensibilité à cette formulation avec des zones d’inhibition ayant des diamètres > 8mm.

Conclusion : Les résultats, concluant sur la stabilité et l’efficacité in vitro de l’émulgel à 5% d’HE d’OG, ouvrent la voie à la réalisation d’une étude clinique avant mise sur le marché.
Fabrication d’une crème à base de l’extrait hydro-éthanolique des feuilles de Terminalia glaucescens (combretaceae) et évaluation in vivo de l’activité antimycosique
Authors: Makeu Sokamté Olive , Foutse Yimta , Mandengue Christine , Djoko Ernest , Wouessidjewe Denis
Published: December 2023

Introduction : Les mycoses superficielles cutanées sont relativement fréquentes et la chimiorésistance aux antifongiques chimiques incite à rechercher de nouveaux médicaments. Terminalia glaucescens est une plante réputée en médecine traditionnelle comme active sur les micro-organismes pathogènes. Une crème à base d’un extrait de la plante a été fabriquée puis évaluée sur le plan clinique.

Méthodologie : Un extrait hydro-éthanolique a été préparé à partir des feuilles. Ensuite, une crème lipophile/hydrophile contenant 2,88 % de l’extrait a été préparée. Les contrôles de qualité physico- chimiques et pharmaco-techniques ont été réalisés à savoir : le sens de l’émulsion, l’homogénéité, la stabilité, la qualité microbiologique, la rhéologie et le dosage des polyphénols totaux. Enfin, sous la supervision d’une praticienne dermatologue, une évaluation clinique a été réalisée sur 83 volontaires dont : 10 pour l’évaluation de la tolérance et de l’acceptabilité de la crème, 4 cas de dermatophytie de la peau glabre, 68 cas de teignes tondantes et 1 cas de dartre.

Résultats : L’extrait hydro-éthanolique contient des polyphénols totaux à hauteur de 349,92 ± 0,002 mg EAG/g. La crème fabriquée (3 lots de 500 g et 2 lots de 1 kg) a présenté une tolérance cutanée satisfaisante. Les contrôles de qualité physico-chimiques et pharmaco-techniques habituels sont conformes. Le produit fini dénommé Makodermâ cream s’est avéré efficace pour le traitement des dermatophyties de la peau glabre (100 %), sur les teignes (75 %), mais pas sur le cas de dartre. La comparaison a été réalisée avec le Kétoconazole cream 2%, efficace sur la dermatophytie de la peau glabre (100 %) mais pas sur les teignes.

Conclusion : Dans les limites de notre étude, la crème de Terminalia glaucescens, Makodermâ cream, s’est avérée plus efficace que Kétoconazole cream 2% sur les teignes. Ces résultats permettent de positionner ce potentiel médicament traditionnel amélioré comme une alternative thérapeutique dans la prise en charge des teignes.
Elaboration d’un lait cosmétique antimicrobien naturel
Authors: Kéké Margery Claude-Charlène , Okou Obou Constantin , Kra Adou Koffi Mathieu
Published: December 2023

Introduction : Le présent travail est particulièrement orienté dans la formulation d’un lait antimicrobien à base de plante médicinale dans le but de valoriser celle-ci. Aussi de traiter des affections cutanées à partir de substances naturelles qui sont jugées moins agressives pour la peau.

Méthodologie : Pendant cette étude, l’extrait éthanolique 70 % de Terminalia catappa L. (Combretaceae) a été incorporé dans un lait. Le lait obtenu a été stable, homogène, onctueux et s’écoulait facilement. Ensuite, ce lait a été testé sur les affections cutanées (dermatoses).

Résultats : Les résultats ont révélé que ce lait antimicrobien avait une bonne activité antimicrobienne car son action a permis de traiter les différentes pathologies cutanées (dartre, teigne, acnés) avec une amélioration de la partie de la peau traitée des patients.

Conclusion : Ce lait peut être une source indéniable pour la mise au point des médicaments traditionnels améliorés (MTA) contre les dermatoses.

Mots clés :

Introduction : Le présent travail est particulièrement orienté dans la formulation d’un lait antimicrobien à base de plante médicinale dans le but de valoriser celle-ci. Aussi de traiter des affections cutanées à partir de substances naturelles qui sont jugées moins agressives pour la peau.

Méthodologie : Pendant cette étude, l’extrait éthanolique 70 % de Terminalia catappa L. (Combretaceae) a été incorporé dans un lait. Le lait obtenu a été stable, homogène, onctueux et s’écoulait facilement. Ensuite, ce lait a été testé sur les affections cutanées (dermatoses).

Résultats : Les résultats ont révélé que ce lait antimicrobien avait une bonne activité antimicrobienne car son action a permis de traiter les différentes pathologies cutanées (dartre, teigne, acnés) avec une amélioration de la partie de la peau traitée des patients.

Conclusion : Ce lait peut être une source indéniable pour la mise au point des médicaments traditionnels améliorés (MTA) contre les dermatoses.
Cadres éthique et réglementaire des essais cliniques des médicaments traditionnels à base de plantes
Authors: Sangho Aboubacar , Ouoba Kampadilemba , Sanogo Rokia , Semdé Rasmané
Published: December 2023

Le recours à la médecine traditionnelle ne cesse de croître dans le monde. C’est ainsi qu’en Afrique, les médicaments traditionnels à base de plantes (MTP) dont la qualité, l’efficacité et l’innocuité sont démontrées constituent une alternative crédible à l’accès aux soins de santé. Cette revue de la littérature visait à faire le point des cadres éthique et réglementaire des essais cliniques applicables aux MTP. Elle est basée sur des recherches dans Scopus, Science Direct et Medline à l’aide de mots clés en anglais se rapportant au sujet. La littérature scientifique indique que les cadres éthique et réglementaire existant sont le plus souvent édictés sous forme de recommandations dans le monde, qui doivent être transcrites dans les législations sous-régionales ou nationales pour jouir d’une force contraignante. En Afrique de l’Ouest en particulier, il n’existe pas de cadre harmonisé contraignant et la pratique des essais cliniques des MTP reste faible. Cependant, la législation européenne promet l’expérience d’usage traditionnel comme mesure d’exemption d’essais cliniques pour les médicaments à base de plantes à travers la Directive n°2004/24/CE. Il en est de même en Afrique pour les médicaments traditionnels des catégories 1 et 2. Mais pour l’approbation à grande échelle des médicaments traditionnels des catégories 3 et 4, les essais cliniques s’avèrent indispensables. Un financement domestique durable et une réglementation adaptée aux contextes socioculturels demeurent les défis majeurs de la mise en œuvre des essais cliniques des MTP en Afrique. Relever ces défis permettra d’améliorer fortement la production locale des phytomédicaments dans les pays africains.
Etude ethnobotanique et ethnopharmacologique des plantes à activité cicatrisante au Burkina Faso
Authors: Traoré Safiatou , Gasbeogo Geoffroy Wendpanga , Zimé-Diawara Hermine , Semdé Rasmané
Published: December 2023

Introduction : Les plaies constituent un problème de santé publique, particulièrement les plaies chroniques. Leur prise en charge représente un coût considérable du fait qu’elle exige une longue période de traitement et est coûteuse. Les populations à faible ou moyen revenu se tournent vers la phytothérapie en raison de son coût relativement abordable. Cette étude avait pour but d’approfondir et pérenniser les connaissances sur les plantes utilisées dans la prise en charge des plaies au Burkina Faso.

Matériels et méthodes : L’enquête s’est déroulée au Burkina Faso de Mars à Mai 2023. L’entretien était la technique d’enquête utilisée. Les personnes interrogées étaient les tradipraticiens de santé (TPS) ayant une expérience dans l’utilisation des plantes dans le traitement des plaies.

Résultats : Au total 112 TPS ont été enquêtés. Ils avaient un âge moyen de 58,71 ans. Les principales sources de savoir étaient la transmission familiale, l’initiation par un autre TPS et le don de la nature. Les plaies traitées étaient principalement causées par les accidents, les brûlures et les infections. Pour la prise en charge, 72 plantes appartenant à 29 familles ont été citées. Les plantes majoritaires étaient Lannea microcarpa Engl. Et K. Krause (Anacardiaceae), Khaya senegalensis (Desr) A. Juss. (Meliaceae), Tamarindus indica L. (Fabaceae), de Ximenia americana L. (Ximeniaceae)

Conclusion : L’enquête ethnobotanique a permis d’identifier 72 espèces de plantes appartenant à 29 familles. Les plantes les plus citées feront l’objet d’une évaluation in vitro de leur activité cicatrisante.
Contribution of research institutions to the development of the pharmaceutical industry: case of scientific works carried out at the faculty of pharmacy of Abidjan
Authors: Amoukou-N'guessan Anne-Cinthia , Alloukou-Boka Paule Mireille , Soro Tcherignimin Grâce , Koffi Kan Daniel , Aka Any-Grah Armelle Sandrine , Amari Antoine Serge
Published: December 2023

Introduction: Works produced within universities and research institutes aim to provide high innovative technological or sociocultural solutions to society's challenges. Pharmaceutical industrialization is a socio-health issue in Côte d'Ivoire. Indeed the pharmaceutical production, although essential, is still in its infancy. Our objective is to take stock of the works carried out on this activity within the faculty of Pharmacy in Côte d'Ivoire in order to assess the contribution of this unit of research to its boom.

Methodology: We’ve listed the theses and dissertations defended on the pharmaceutical production since the opening of the faculty, have described them and then we’ve analysed the results and recommendations of the authors of works.

Results: During this preliminary study, out of the 25 documents available, 18 (72.0%) of the works focused on the development of galenic and cosmetic formulations, including 08 (32.0%) based on natural substances, in terms of development and evaluation of formulation parameters; 04 (16,0%) focused on the difficulties of the industrial process and 03 (12.0%) on the political and regulatory aspects. The works on the regulation of the activity, which was more transversal, presented the legal,

 

institutional and political framework as harmonious, but highlighted other factors that need to be legislated.

Conclusion: The preponderance of works on technical aspects that take into account our local realities confirms the expected contribution of universities through basic and applied research. The regulation remains an essential point also to implementate and organize. State support and public-private partnerships are still needed for the pharmaceutical industrialization.
Evaluation de la qualité des disques d’Amoxicilline et d’Amoxicilline + Acide clavulanique utilisés au Burkina Faso
Authors: Nikiéma Ouéogo , Diallo Djibril , Goumbri Bertrand , Moné-Bassavé Bélinda , Belem Mohamed , Yaméogo B. Gérard Josias , Ouédraogo Abdoul Salam , Kabré Elie , Semdé Rasmané
Published: December 2023

Introduction : Les disques d’antibiotiques utilisés dans les laboratoires d’analyses médicales proviennent de plusieurs fabricants et fournisseurs et doivent répondre à des exigences strictes de qualité. Cette étude a été entreprise pour évaluer la qualité des disques d’Amoxicilline et d’Amoxicilline

+ acide clavulanique utilisés au Burkina Faso.

Matériel et méthodes : Une enquête sur l’utilisation des disques d’antibiotiques a été réalisée dans 20 laboratoires sites sentinelles de surveillance de la RAM. Des échantillons de disques d’Amoxicilline et d’Amoxicilline + acide clavulanique de quatre fabricants ont été collectés auprès de certains de ces laboratoires et de fournisseurs de disques d’antibiotiques. La qualité des disques d’Amoxicilline et des disques d’Amoxicilline + acide clavulanique a été évaluée en testant leur efficacité sur des souches d’Escherichia coli ATCC 25922 et Staphylococcus aureus ATCC 25923 et en dosant les antibiotiques par chromatographie liquide à haute performance.

Résultats : Escherichia coli ATCC 25922 et Staphylococcus aureus ATCC 25923 étaient résistantes à 30,0 % pour les disques d’Amoxicilline + acide clavulanique et 55,6 % pour les disques d’Amoxicilline testés. Par ailleurs, les essais de dosage de l’amoxicilline ont révélé que 22,2% et 45,5% respectivement des disques d’Amoxicilline et des disques d’Amoxicilline + acide clavulanique contrôlés étaient conformes aux spécifications de l’OMS. Aucun échantillon ne contenait une teneur en Acide clavulanique conforme à la spécification.

Conclusion : Cette étude révèle que la majorité des disques d’Amoxicilline et d’Amoxicilline + acide clavulanique contrôlés n’était pas conformes aux spécifications de qualité. Son extension à un nombre plus important d’antibiotiques permettra de mieux documenter la qualité des disques d’antibiotiques.
Japanese Noun Phrase on Twitter Trending Topic
Authors: Hermawan Gede Satya
Published: December 2023

This paper discussed a Japanese noun phrase as hashtag Twitter. The research was conducted by collecting data for 1 month in September 2022. The data is not limited to a single chunky noun phrase, but noun phrases as constituents are also discussed in this paper. The descriptive qualitative method will describe the meaning of the phrase, and syntax will be used to identify the structure. The results reflect the used noun phrased as a hashtag, created simply as structure, but complex as semantically. The single hashtag has a discourse meaning behind it. Other than that, founded a treatment spoken language as writing text, and the users naturally find the meaning behind of it. This kind of situation indicates a premature sign of spoken language can fully understand without syntax marker on it (the spoken language always pragmatically helped by gesture, expression, and intonation).
The Anaysis of Using Verbs in Descriptive Paragraph in Semester II STBA JIA in Academic Year 2022/2023
Authors: Surista Ade , Setiawan Wawan
Published: December 2023

This research aimed to describe how the student’s constructing sentences in their writing descriptive paragraph. The sample uses are the students of semester II class A, B and evening class with the total number of students are 41 students. The instrument uses in this research are test and interview. The researcher limits the sentences constructing are simple, compound and complex sentences. It assumed that the students are able to construct and use simple sentences, compound sentences and complex sentence in developing descriptive writing. The result show that from the first test, the average is 79. In the second test, from 41 students, there are 12 students do all correct sentences. There are 9 students made mistakes in simple sentence, with 10 mistakes. For compound sentence, there are 18 students who made 35 mistakes. and complex sentences, there are 18 students who made 41 mistakes.
Konsep Slot pada Kelas Kata yang Sama dalam Kalimat Sederhana Bahasa Inggris
Authors: Hadi Imron , Arvian Elsan
Published: December 2023

Penelitian ini bertujuan untuk mengetahui alasan mengapa di antara slot-slot dalam kalimat sederhana bahasa Inggris ada yang memiliki hubungan dengan slot lain dan ada yang tidak memiliki hubungan. Metode yang digunakan dalam penelitian ini adalah metode kualitatif deskriptif dengan pendekatan analisis isi (Content Analysis). Penulis mengumpulkan data tentang kalimat sederhana yang berjenis transitif dalam cerita pendek The Queen of Spades and Other stories by Aleksandr Pushkin. Teknik yang dilakukan untuk mendapatkan data adalah sebagai berikut: (1) mencari kalimat sederhana yang transitif (2) Menghubungkan slot-slot dalam kalimat sederhana tersebut dan mencari slot-slot yang memiliki hubungan dan yang tidak memiliki hubungan (3) membuktikan data yang telah ditemukan dan menjelaskannya berdasarkan ilmu morfologi yang diambil dari teori Katamba (1993) dan ilmu syntaksis yang diambil dari teori Noel Burton. Dari analisis tersebut dapat disimpulkan bahwa dari 4 objek data, terdapat 4 data yang memiliki hubungan slot yang sama dalam bentuk open classes dan 1 dalam bentuk closed class .Penelitian ini dilakukan agar kita memahami proses terbentuknya kalimat sederhana bahasa Inggris dari peran interaksi antara morfologi dan syntaksis.
Impact Of Green Manuring Preceding To Rice Crop On Rice Yield And Cost Of Cultivation In Nizamabad District Of Telangana State
Authors:   Department of Crop Production, Krishi Vigyan Kendra, Rudrur (Nizamabad), India, Suresh M. , Kumar P. Vijay , Rajkumar B. V. , Swetha M. , Srilaxmi B. , Naveen Kumar S. , Balazzi R.V.T , Vijayalaxmi D. ,   Department of Horticulture, Krishi Vigyan Kendra, Rudrur (Nizamabad), Telangana, India,   Department of Agril. Extension, Krishi Vigyan Kendra, Rudrur (Nizamabad), Telangana, India,   Department of Agromet, Krishi Vigyan Kendra, Rudrur (Nizamabad), Telangana, India,   Krishi Vigyan Kendra, Rudrur (Nizamabad), Telangana, India,   Department of AICRP on Forage crops, Rajendra Nagar, PJTSAU, Hyderabad, India,   Department RARS, Palem, PJTSAU Hyderabad India
Published: December 2023

Field experiments were conducted at farmer’s fields on the application of green manure Dhaincha (Sesbania rostrata) as preceding crop to rice to improve yields with green manuring and also increase the status of soil physical and chemical properties, soil organic carbon and pH towards neutral. The performance of an entire system is evaluated by front-line demonstration under the control of Krishi Vigyan Kendra, Nizamabad (Rudrur) under field conditions at s farmer’s field. Sesbania seeds were sown @ 45-50 kg/ha. 5-6 weeks old green manuring crops were chopped into pieces and incorporated in the fields with a tractor drawn rotovator. With the incorporation of green manure crops, the average rice yield was increased by 8.36%. The demonstration was done on around 8 hectares covering 20 rice-cultivating farmers. During 2019-21 years with conventional practice, three years average no. of panicles per meter square was only 173 whereas it was 182 in the demonstration plot, similarly, the average grain yield was 6467 kg/ha and 7008 kg/ha in farmer’s practice and demonstration plots respectively. The average net return was only Rs.67,092 per hectare from farmer’s practice, whereas it with the incorporation of green manure crop before rice was Rs.82,310 in demonstration plots respectively. Similarly, the average cost to-benefit ratio was 2.24 in the conventional method and later it was noticed 2.69 in the demo plot. Hence, the farmers growing rice in the wetland ecosystem are advised to take up green manure followed by transplanted rice as a cropping pattern for sustainable yield and economic returns.
Genetic Variability And Correlation Studies For Growth, Yield And Quality In Strawberry (Fragaria Ananassa Duch.)
Authors: M.I Manivannan, , V Premalakshmi, , Mani, M. Theradi , L Allwin , C Ravindran,
Published: December 2023

The traits viz., fruit nutritional quality, yield, day neutral nature to be improved in strawberry and hence the present study was undertaken to identify the nature of variability present in the promising advanced strawberry genotypes and to detect the association among yield and yield component traits in strawberry (Fragaria × ananassa Duch.). Fourteen advanced genotypes were evaluated to study genetic variation and the relationship between yield and its components using a randomized complete block design during the year 2021. The results showed significant variance among genotypes of all traits. The phenotypic coefficient of variation (PCV) for all the characters was slightly higher than the genotypic coefficient of variation (GCV), which signified the presence of environmental influence to some degree in the phenotypic expression of characters. The leaf area index had the highest PCV (30.71) and GCV (30.82). The genetic advance was recorded maximum for fruit yield per plant (228.24), whereas genetic advance as a percent of mean was highest for leaf area index (63.05) followed by shelf life of fruits (61.95). The highest heritability (h2, 95.22) was coupled with higher genetic advance (228.24) estimated for fruit yield per plant, which indicated that the character is controlled by additive genes and therefore further improvement could be brought by selection. Being octoploid, the inheritance of traits is complex in strawberry and the identified heritable traits in the study would be helpful for strawberry improvement breeding programs. Fruit yield was significantly and positively associated with most of the characteristics except flowering duration, fruiting duration, and volume of fruit at both genotypic and phenotypic levels; therefore, these are important prerequisites to formulate a successful strawberry improvement program.
Effect Of Hardening On Germination And Seedling Characters Of Maize (Zea Mays L)
Authors:   Department of Agriculture, Kalasalingam School of Agriculture and Horticulture, Kalasalingam Academy of Research and Education, Krishnankoil-626126, Tamil Nadu, Indi, Selvarani K Selvarani K , Prabha V Vijay , M Jayanthi , Kumar I. J Isaac Prem ,   Department of Horticulture, Kalasalingam School of Agriculture and Horticulture, Kalasalingam Academy of Research and Education, Krishnankoil-626126, Tamil Nadu, India
Published: December 2023

The ideal temperature is necessary for the maize crop to provide the highest harvest yield. Environmental stress elements such as abiotic and biotic stress factors are expected to intensify and become more widespread as a result of climate change. Drought, temperature, and salinity are the key factors affecting maize output globally. Various management practices may help in contributing tolerance to the plants against adverse environmental impact, and seed hardening is one among them. The experiment was conducted in the laboratory of Seed science and Technology, Department of Agriculture, Kalasalingam School of Agriculture and Horticulture, Krishnankoil, Tamil Nadu to study the effect of various hardening treatments in maize seeds. Maize seeds were hardened with the following chemicals at varying concentrations for 12 hours viz., T0 – Control, T1 – Distilled water, T2 – Boric acid (0.5%), T3 – Boric acid (1.0%), T4 – Boric acid (1.5%), T5 – KNO3 (0.5%), T6 – KNO3 (1.0%), T7 – KNO3 (1.5%), T8 – KH2PO4 (0.5%), T9 – KH2PO4 (1.0%) and T10 – KH2PO4 (1.5%). Significant differences were found between control and hardening treatments. Maximum germination percentage, shoot, and root length, seedling length, fresh and dry weight of the seedling vigor index were observed for the seeds treated with 1.5% KNO3. This experiment also showed the positive influence of KH2PO4 (1.5%) in various seedling characters followed by 1.5% KNO3. This study might help to improve the seedling character with the help of seed-hardening treatments to withstand adverse abiotic stress situations
Concurrent Infection of Dengue and Malaria: An Unusual Case Report
Authors: Baftahul Khairi Andri , Liansyah Sihite Perdana , Azalia Rauzia
Published: December 2023

Plasmodium knowlesi is one of the most common causes of Malaria in humans. Although several reported cases of dengue and Malaria occur together, only a few cases have been reported in Southeast Asia, including Indonesia. This study aims to provide additional insight into the epidemiology and clinical aspects of Plasmodium knowlesi (P. knowlesi) malaria infection and dengue fever that occur concurrently in Southeast Asia, particularly Indonesia. A 36-year-old male patient with a history of travel to the mountainous area of Lhoknga and a fever for five days sought treatment at the emergency department of Meuraxa Hospital. During 11 days of treatment, the patient underwent a routine haematology examination every 24 hours. The average platelet count during the first eight days was around 50,000, with an increase after anti-malarial treatment on the eighth day and marked clinical improvement. The patient was discharged on day 10 with no signs of bleeding or hemolysis during treatment. Diagnosis involved blood smears and hematologic examination, confirming dengue fever with P. knowlesi malaria infection. These findings emphasize the importance of thorough history taking, physical examination, and supporting investigations to diagnose these two conditions together. The results of this study may provide critical support for case management involving malaria infection and dengue fever, with a focus on platelet monitoring as an indicator of response to treatment in the Southeast Asian region.
Pertanggungjawaban Pelaku Tindak Pidana Kekerasan dengan Tenaga Bersama yang Mengakibatkan Luka pada Korban
Authors: Hidayat Alian Hadi , Hapsari Recca Ayu
Published: December 2023

Permasalahan masalah dalam penelitian ini yakni bagaimana pertanggungjawaban pelaku tindak pidana kekerasan dengan tenaga bersama yang mengakibatkan luka pada korban dan bagaimana pertimbangan hakim dalam meumutus perkara pidana kekerasaan dengan tenaga bersama yang mengakibatkan luka pada korban pada Putusan Nomor 59/Pid.B/2022/PN Tjk. Pendekatan yang dilakukan dalam penelitian ini adalah secara yuridis normatif dan empiris. Bentuk pertanggungjawaban pelaku tindak pidana kekerasan dengan tenaga bersama yang mengakibatkan luka pada korban Jaksa penuntut umum mengajukan dakwaan Pasal 170 ayat 2 ke 1 kuhpidana dengan pidana penjara selama 2 (dua) tahun dan 6 (enam) bulan dinilai sesuai dikarenakan jaksa penuntut umum melihat Terdakwa selama masa penahanan berprilaku baik, koperatif dan mengakui kesalahannya serta Terdakwa tidak akan mengulangi perbuatan kekerasan dengan tenaga bersama yang mengakibatkan luka pada korban. Selain itu korban tidak mengajukan tuntutan lebih terhadap tuntutan yang diajukan oleh Penuntut Umum kepada Terdakwa. Pertimbangan Hakim secara Yuridis dapat dilihat di dalam persidangan bahwa Penuntut Umum menghadirkan saksi-saksi yang menjelaskan kejadian perkara, barang bukti yang digunakan oleh Terdakwa, surat hasil visum et repertum dan keterangan Terdakwa sendiri yang telah membenarkan telah terjadi peristiwa tindak pidana kekerasan dengan tenaga bersama yang mengkibatkan luka pada korban.  Selain itu pertimbangan Hakim secara Non Yuridis bahwa Hakim berpendapat perbuatan yang dilakukan oleh Terdakwa dengan keadaan yang memberatkan yakni perbuatan Terdakwa meresahkan masyarakat. Sedangkan keadaan yang meringankan yakni Terdakwa bersikap sopan dalam persidangan, Terdakwa menyesali perbuatannya; Terdakwa belum pernah dihukum
KEEFEKTIFAN PELAKSANAAN PROGRAM UPAYA KHUSUS KOMODITAS JAGUNG DI KABUPATEN KETAPANG
Authors: Heristi Veny , Sudrajat Jajat , Gafur Sutarman
Published: December 2023

Keefektifan program Upsus yang menjadi agenda nasional masih memerlukan pengujian di berbagai tempat. Penelitian ini bertujuan untuk menganalisis keefektifan pelaksanaan program Upsus dalam pengembangan komoditas jagung di Kecamatan Sungai Melayu Rayak Kabupaten Ketapang dan menganalisis  produktivitas usahatani  peserta sebelum dan sesudah program. Studi kasus ini menerapkan metode survey dengan mewawancarai 40 petani dari empat desa yang mengikuti program. Hasil penelitian menunjukkan bahwa proses pelaksanaan siklus program dan pemanfaatan bantuan yang sudah tercapai cukup baik. Indikator keberhasilan lainnya dilihat dari sosialisasi yang dapat menjangkau kebanyakan petani, peningkatan luas tanam, dan adanya peningkatan produktivitas. Adapun kelemahannya dilihat dari kurang tepatnya waktu pelaksanaan program yang berdampak pada jadwal tanam.
PENGARUH PEMUPUKAN FOSFAT DAN KALIUM TERHADAP PERTUMBUHAN DAN HASIL GABAH PADI HITAM DI SAWAH TADAH HUJAN
Authors: Heny Kurnia Nyemas , Sasli Iwan , Wasian Wasian
Published: December 2023

Padi (Oriza sativa.L) beras hitam merupakan salah satu varietas lokal yang memiliki kandungan antosianin tinggi terletak pada lapisan perikarp yang memiliki fungsi nutrisi yang bermanfaat bagi kesehatan. Gabah padi beras hitam banyak yang kosong/hampa karena kurang maksimalnya pemupukan, terutama pemupukan kalium dan fosfat. Pemanfaatan tanah aluvial untuk budidaya padi beras hitam dapat dilakukan dengan pemupukan yang berimbang. Penelitian ini bertujuan untuk mengetahui pengaruh pemupukan fosfat dan kalium terhadap pertumbuhan dan produksi gabah padi beras hitam pada tanah aluvial. Penelitian menggunakan model Rancangan Acak Lengkap (RAL) dengan dua faktor yaitu faktor pupuk KCl terdiri dari empat taraf yakni k0 tanpa perlakukan,k1=20 g/petak, k2=40 g/petak, k3=60g/petak dan faktor kedua adalah fosfat terdiri dari empat taraf yaitu p0 tanpa perlakukan,p1=20 g/petak, p2=40 g/petak, p3=60g/petak. Masing-masing perlakuan diulang sebanyak tiga kali sehingga terdapat 48 satuan petak percobaan. Hasil penelitian menunjukkan bahwa terjadi interaksi antar pelakuan terhadap berat 1000 butir gabah sedangkan pemberian pupuk kalium berpengaruh nyata terhadap jumlah anakan produktif, gabah kering panen, gabah kering giling dan berat 1000 butir gabah dan pemberian pupuk fosfat hanya berpengaruh nyata terhadap jumlah anakan produktif dengan dosis yang dianjurkan sebanyak 40g/petak karena memberikan hasil yang lebih tinggi dibandingkan dengan yang lain yaitu sebesar 17,95 anakan produktif.
DETERMINASI DAYA SAING AGROINDUSTRI LIDAH BUAYA DI KOTA PONTIANAK
Authors: Desita Jumiar Alfath , K. Daryanto Heny , M. Baga Lukman
Published: December 2023

Penelitian ini bertujuan mengidentifikasi faktor-faktor penentu daya saing agroindustri lidah buaya dan menetapkan prioritas strategi peningkatan daya saing agroindustri lidah buaya di Kota Pontianak. Penelitian dilakukan di Kota Pontianak sebagai salah satu sentra produksi lidah buaya di Indonesia. Data primer dikumpulkan dari pengolah lidah buaya dan pakar dengan melakukan wawancara dan pengisian kuesioner, sedangkan data sekunder bersumber dari BPS, Kementerian Perindustrian, Dinas Pertanian, dan Aloe Vera Center. Untuk menjawab tujuan penelitian digunakan metode Proses Hirarki Analitik (PHA), dengan pendekatan teori dayasaing Diamond Porter. Data PHA diperoleh dari 2 orang pakar yang mengisi kuesioner berupa penilaian komparasi berpasangan, selanjutnya data diolah menggunakan Expert Choice. Hasil penelitian menunjukkan bahwa faktor-faktor penentu dayasaing agroindustri lidah buaya dengan bobot tertinggi adalah kondisi permintaan (0.420) dan kondisi sumberdaya (0.300). Prioritas strategi yang dapat dilakukan adalah memproduksi produk sesuai dengan kualitas permintaan pasar lokal, nasional, dan internasional (0.196), dan menciptakan inovasi produk untuk semua segmen permintaan (0.190). Aktor yang berperan langsung dalam upaya peningkatan dayasaing agroindustri lidah buaya di Kota Pontianak adalah pihak swasta yakni pengusaha dan petani lidah buaya (0.634). Agar peningkatan dayasaing agroindustri lidah buaya di Kota Pontianak dapat tercapai, diperlukan perbaikan-perbaikan berupa kualitas dan jenis produk, design kemasan, dan segmen pasar, dengan cara pemerintah daerah secara aktif memberikan pembinaan dan pelatihan kepada pengolah lidah buaya dan turut serta mendukung terbentuk kelembagaan atau koperasi lidah buaya di Kota Pontianak
Tanggap Kedaruratan Tersedak Anak Dan Penatalaksanaan Pada Keluarga Di Kelurahan Balocci Baru Kec. Balocci Kab. Pangkep
Authors: Salaman Alhidayat Nurun , Esti Handayani Dwi , Halimah Nur , Samsir Samsir , Alamsyah Alamsyah , Hasbullah Hasbullah , Sulasri Sulasri , Botutihe Fauziah
Published: December 2023

Choking is a condition where the upper airway is blocked by food or other objects which causes breathing problems. The method used in this Community Service Activity (PKM) starts from the initial survey, problem formulation, pre test, activity implementation and post test. The results of the activity showed that there was a significant increase in the level of knowledge of parents in providing first aid for choking events in children. The results of the presentation showed that 63% experienced a good increase in knowledge and 37% experienced a moderate increase. It is hoped that this community service activity will help the community, especially parents who have school-age children who are prone to choking, can provide first aid to prevent disability or death