bluuebunny/crossref_metadata_2025 huggingface dataset:
Ca2+/Calmodulin Complex Triggers CAMTA Transcriptional Machinery Under Stress in Plants: Signaling Cascade and Molecular Regulation
Authors: Iqbal Zahra , Shariq Iqbal Mohammed , Singh Surendra Pratap , Buaboocha Teerapong
Published: December 2020

Calcium (Ca2+) ion is a critical ubiquitous intracellular second messenger, acting as a lead currency for several distinct signal transduction pathways. Transient perturbations in free cytosolic Ca2+ ([Ca2+]cyt) concentrations are indispensable for the translation of signals into adaptive biological responses. The transient increase in [Ca2+]cyt levels is sensed by an array of Ca2+ sensor relay proteins such as calmodulin (CaM), eventually leading to conformational changes and activation of CaM. CaM, in a Ca2+-dependent manner, regulates several transcription factors (TFs) that are implicated in various molecular, physiological, and biochemical functions in cells. CAMTA (calmodulin-binding transcription activator) is one such member of the Ca2+-loaded CaM-dependent family of TFs. The present review focuses on Ca2+ as a second messenger, its interaction with CaM, and Ca2+/CaM-mediated CAMTA transcriptional regulation in plants. The review recapitulates the molecular and physiological functions of CAMTA in model plants and various crops, confirming its probable involvement in stress signaling pathways and overall plant development. Studying Ca2+/CaM-mediated CAMTA TF will help in answering key questions concerning signaling cascades and molecular regulation under stress conditions and plant growth, thus improving our knowledge for crop improvement.
Mitochondrial Fostering: The Mitochondrial Genome May Play a Role in Plant Orphan Gene Evolution
Authors: O’Conner Seth , Li Ling
Published: December 2020

Plant mitochondrial genomes exhibit unique evolutionary patterns. They have a high rearrangement but low mutation rate, and a large size. Based on massive mitochondrial DNA transfers to the nucleus as well as the mitochondrial unique evolutionary traits, we propose a “Mitochondrial Fostering” theory where the organelle genome plays an integral role in the arrival and development of orphan genes (genes with no homologs in other lineages). Two approaches were used to test this theory: (1) bioinformatic analysis of nuclear mitochondrial DNA (Numts: mitochondrial originating DNA that migrated to the nucleus) at the genome level, and (2) bioinformatic analysis of particular orphan sequences present in both the mitochondrial genome and the nuclear genome of Arabidopsis thaliana. One study example is given about one orphan sequence that codes for two unique orphan genes: one in the mitochondrial genome and another one in the nuclear genome. DNA alignments show regions of this A. thaliana orphan sequence exist scattered throughout other land plant mitochondrial genomes. This is consistent with the high recombination rates of mitochondrial genomes in land plants. This may also enable the creation of novel coding sequences within the orphan loci, which can then be transferred to the nuclear genome and become exposed to new evolutionary pressures. Our study also reveals a high correlation between the amount of mitochondrial DNA transferred to the nuclear genome and the number of orphan genes in land plants. All the data suggests the mitochondrial genome may play a role in nuclear orphan gene evolution in land plants.
Simultaneous CRISPR/Cas9 Editing of Three PPO Genes Reduces Fruit Flesh Browning in Solanum melongena L.
Authors: Maioli Alex , Gianoglio Silvia , Moglia Andrea , Acquadro Alberto , Valentino Danila , Milani Anna Maria , Prohens Jaime , Orzaez Diego , Granell Antonio , Lanteri Sergio , Comino Cinzia
Published: December 2020

Polyphenol oxidases (PPOs) catalyze the oxidization of polyphenols, which in turn causes the browning of the eggplant berry flesh after cutting. This has a negative impact on fruit quality for both industrial transformation and fresh consumption. Ten PPO genes (named SmelPPO1-10) were identified in eggplant thanks to the recent availability of a high-quality genome sequence. A CRISPR/Cas9-based mutagenesis approach was applied to knock-out three target PPO genes (SmelPPO4, SmelPPO5, and SmelPPO6), which showed high transcript levels in the fruit after cutting. An optimized transformation protocol for eggplant cotyledons was used to obtain plants in which Cas9 is directed to a conserved region shared by the three PPO genes. The successful editing of the SmelPPO4, SmelPPO5, and SmelPPO6 loci of in vitro regenerated plantlets was confirmed by Illumina deep sequencing of amplicons of the target sites. Besides, deep sequencing of amplicons of the potential off-target loci identified in silico proved the absence of detectable non-specific mutations. The induced mutations were stably inherited in the T1 and T2 progeny and were associated with a reduced PPO activity and browning of the berry flesh after cutting. Our results provide the first example of the use of the CRISPR/Cas9 system in eggplant for biotechnological applications and open the way to the development of eggplant genotypes with low flesh browning which maintain a high polyphenol content in the berries.
Beyond the Words: Comparing Interpersonal Engagement Between Maternal and Paternal Infant-Directed Speech Acts
Authors: Kokkinaki Theano , Vasdekis Vassilis G. S.
Published: December 2020

The present study investigates the way infants express their emotions in relation to parental feelings between maternal and paternal questions and direct requests. We therefore compared interpersonal engagement accompanying parental questions and direct requests between infant–mother and infant–father interactions. We video-recorded spontaneous communication between 11 infant–mother and 11 infant–father dyads—from the 2nd to the 6th month—in their home. The main results of this study are summarized as follows: (a) there aresimilaritiesin the way preverbal infants use their affections in spontaneous interactions with their mothers and fathers to express signs of sensitivity in sharing knowledge through questions and direct requests; and (b) the developmental trajectories of face-to-face emotional coordination in the course of parental questions descend in a similar way for both parents across the age range of this study. Regarding the developmental trajectories of emotional non-coordination, there is evidence of a linear trend in terms of age difference between the parents’ gender with fathers showing the steeper slope. The results are discussed in relation to the theory of intersubjectivity.
What Influences Participation in Non-formal and Informal Modes of Continuous Vocational Education and Training? An Analysis of Individual and Institutional Influencing Factors
Authors: Lischewski Julia , Seeber Susan , Wuttke Eveline , Rosemann Therese
Published: December 2020

Participation in further education is a central success factor for economic growth and societal as well as individual development. This is especially true today because in most industrialized countries, labor markets and work processes are changing rapidly. Data on further education, however, show that not everybody participates and that different social groups participate to different degrees. Activities in continuous vocational education and training (CVET) are mainly differentiated as formal, non-formal and informal CVET, whereby further differences between offers of non-formal and informal CVET are seldom elaborated. Furthermore, reasons for participation or non-participation are often neglected. In this study, we therefore analyze and compare predictors for participation in both forms of CVET, namely, non-formal and informal. To learn more about the reasons for participation, we focus on the individual perspective of employees (invidual factors, job-related factors, and learning biography) and additionally integrate institutional characteristics (workplace and company-based characteristics). The results mainly show that non-formal CVET is still strongly influenced by institutional settings. In the case of informal CVET, on the other hand, the learning biography plays a central role.
Caught in the Crossfire: How Contradictory Information and Norms on Social Media Influence Young Women’s Intentions to Receive HPV Vaccination in the United States and China
Authors: Pan Shuya , Zhang Di , Zhang Jingwen
Published: December 2020

This study uses online survey data from the United States and China to examine how contradictory information and social norms regarding HPV vaccines obtained through social media are related to young women’s attitudes and intentions surrounding HPV vaccination. The results show that exposure to contradictory information on social media had a greater negative association with intentions to receive HPV vaccination among the United States participants than among the Chinese participants, while social norms supporting HPV vaccines had a stronger positive association with intentions to receive HPV vaccination among the Chinese participants than among the United States participants. These findings extend the literature on social media communication regarding HPV vaccination and contribute to our knowledge of cultural contexts that influence intentions to receive HPV vaccination.
Psychological Well-Being, Marital Satisfaction, and Parental Burnout in Iranian Parents: The Effect of Home Quarantine During COVID-19 Outbreaks
Authors: Mousavi Seyyedeh Fatemeh
Published: December 2020

Coronavirus disease 2019 (COVID-19), as an infectious disease, is now prevalent in many countries around the world, which has recently led many governments to home quarantine and impose penalties for violating quarantine. Concerns and stress caused by lockdown and social isolation led to personal and interactive reactions in some families, which are also culturally important to address. This study was administrated to study the psychological well-being and the effect of home quarantine on marital satisfaction (MS) and parental burnout (PB) from parenting responsibilities during the prevalence of COVID-19 in Iranian parents. A total of 213 parents (140 mothers and 73 fathers) voluntarily participated in the online survey in the period of February to mid-April 2020 and completed the 5-item index of the well-being of the World Health Organization (WHO-5), the Kansas Marital Satisfaction Scale (KMSS), and the Parental Burnout Assessment (PBA). The results showed that the effect of home quarantine on MS and PB was not significant in parents (p > 0.01). The interactive effect of home quarantine and gender was not significant on MS and PB (p > 0.01). In addition, the mothers significantly reported higher PB than the fathers, but the fathers had higher scores in MS and psychological well-being (p < 0.01). The effect of some demographic factors on the studied variables was also significant. Supportive resources in family-based culture may play an essential role to reduce the negative effects of stressful situations on family interactions.
Does Inconsistent Social Support Matter? The Effects of Social Support on Work Absorption Through Relaxation at Work
Authors: Xu Shan , Zhang Youxin , Zhang Bingran , Qing Tao , Jin Jiafei
Published: December 2020

Drawing upon the conservation of resources theory and social exchange theory, we examined the effects of family supportive supervisor behavior (FSSB) and family support (FS) on work absorption at the within- and between-person levels. A 10-day study of 91 workers using 710 observations was employed. At the within-person level, the results suggested that daily relaxation at work mediated the relationships between daily FS, daily shifts in FS, and daily work absorption. However, at the between-person level, the results revealed that chronic relaxation at work mediated the relation between the average level of FSSB/FS and chronic work absorption. We conclude that FSSB/FS plays a vital role in relaxation at work and work absorption at the within- and between-person levels.
Influence of Knowledge Management Practices on Entrepreneurial and Organizational Performance: A Mediated-Moderation Model
Authors: Li Cai , Ashraf Sheikh Farhan , Shahzad Fakhar , Bashir Iram , Murad Majid , Syed Nausheen , Riaz Madiha
Published: December 2020

This study aims to identify the influence of knowledge management practices on the entrepreneurial and organizational performance with the mediating effect of dynamic capabilities and moderating role of opportunity recognition. Data were gathered from 486 entrepreneurs and applied a structural equation model to test the hypotheses. We found that knowledge management practices have a positive and significant influence on dynamic capabilities, as well as have a significant impact on entrepreneurial and organizational performance. Moreover, results indicated that dynamic capabilities partially mediate in the relationship between knowledge management practices on entrepreneurial and organizational performance. Furthermore, the relationship between knowledge management practices with entrepreneurial and organizational performance strengthening by opportunity recognition. Further, implications and limitations were discussed in the paper.
Shaping Behaviors Through Institutional Support in British Higher Educational Institutions: Focusing on Employees for Sustainable Technological Change
Authors: Zhao Fuqiang , Ahmed Fawad , Iqbal Muhammad Khalid , Mughal Muhammad Farhan , Qin Yuan Jian , Faraz Naveed Ahmad , Hunt Victor James
Published: December 2020

Technology permeates all walks of life. It has emerged as a global facilitator to improve learning and training, alleviating the temporal and spatial limitations of traditional learning systems. It is imperative to identify enablers or inhibitors of technology adoption by employees for sustainable change in education management systems. Using the theoretical lens of organizational support theory, this paper studies effect of institutional support on education management information systems (EMIS) use along with two individual traits of self-efficacy and innovative behavior of academic employees in British higher educational institutions. Data for this cross-sectional study were collected through a questionnaire completed by 591 academic employees of 23 universities from 10 cities in the United Kingdom. Partial Least Square structural equation modeling was used to analyze data with smartPLS 3.2.9 software. Results indicate that institutional support promotes self-efficacy and innovative behavior that help develop positive employee perceptions. The model explains a 52.9% variance in intention to use. Post-hoc mediation analysis shows that innovativeness and self-efficacy mediate between institutional support and employee technology adoption behavior. As opposed to student samples in past studies on educational technology, this study adds to the literature by focusing on academic employees.
Psychometric Evaluation of the Czech Version of Group Cohesiveness Scale (GCS) in a Clinical Sample: A Two-Dimensional Model
Authors: Klocek Adam , Řiháček Tomáš , Cígler Hynek
Published: December 2020

The Group Cohesiveness Scale (GCS, 7 items) measures patient-rated group cohesiveness. The English version of the scale has demonstrated good psychometric properties. This study describes the validation of the Czech version of the GCS. A total of 369 patients participated in the study. Unlike the original study, the ordinal confirmatory factor analysis (CFA) supported a two-dimensional solution (RMSEA = 0.075; TLI = 0.986). The analysis demonstrated the existence of two moderately to highly associated (r = 0.79) domains of group cohesiveness—affective and behavioral. The two-dimensional model was invariant across genders, age, education, and time (retest after 6 weeks) up to factor means level. Internal consistency reached satisfactory values for both domains (affective, ω = 0.86; behavioral, ω = 0.81). In terms of convergent validity, only weak association was found between the GCS domains and the group working alliance measured by the Group Outcome Rating Scale (GSRS). This is the first revision of the factor structure of the GCS in the European context. The scale showed that the Czech version of the GCS is a valid and reliable brief tool for measuring both aspects of group cohesiveness.
Sentence Context Differentially Modulates Contributions of Fundamental Frequency Contours to Word Recognition in Chinese-Speaking Children With and Without Dyslexia
Authors: Zhang Linjun , Li Yu , Zhou Hong , Zhang Yang , Shu Hua
Published: December 2020

Previous work has shown that children with dyslexia are impaired in speech recognition in adverse listening conditions. Our study further examined how semantic context and fundamental frequency (F0) contours contribute to word recognition against interfering speech in dyslexic and non-dyslexic children. Thirty-two children with dyslexia and 35 chronological-age-matched control children were tested on the recognition of words in normal sentences versus wordlist sentences with natural versus flatF0contours against single-talker interference. The dyslexic children had overall poorer recognition performance than non-dyslexic children. Furthermore, semantic context differentially modulated the effect ofF0contours on the recognition performances of the two groups. Specifically, compared with flatF0contours, naturalF0contours increased the recognition accuracy of dyslexic children less than non-dyslexic children in the wordlist condition. By contrast, naturalF0contours increased the recognition accuracy of both groups to a similar extent in the sentence condition. These results indicate that access to semantic context improves the effect of naturalF0contours on word recognition in adverse listening conditions by dyslexic children who are more impaired in the use of naturalF0contours during isolated and unrelated word recognition. Our findings have practical implications for communication with dyslexic children when listening conditions are unfavorable.
Spatial Mental Transformation Skills Discriminate Fitness to Drive in Young and Old Adults
Authors: Tinella Luigi , Lopez Antonella , Caffò Alessandro Oronzo , Grattagliano Ignazio , Bosco Andrea
Published: December 2020

Literature on driving research suggests a relationship between cognition and driving performance in older and younger drivers. There is little research on adults and driving, despite them being the largest age cohort behind the wheel. Among the cognitive domains, visuospatial abilities are expected to be highly predictive of driving skills and driving fitness. The relationship between specific spatial mental transformation skills (i.e., object and self-based ones) and driving performance has not yet been examined. The present study aimed to investigate the relationship between overall cognitive functioning, self and object-based spatial mental transformation skills, and driving performance in a sample of younger and older adult drivers. Participants were comprised of one hundred younger and 83 older adult Italian drivers. Participants completed a computerized driving test assessing traffic stress resilience, visual and motor reaction time, and the ability to obtain an overview of the traffic scenario (DT, vRT, mRT, and ATAV respectively in the Shufried®-Vienna Test System–DRIVESC). The Mental Rotation Test (MRT) and the Object Perspective Taking Test (OPT) were administered in order to assess object-based and self-based spatial mental transformation skills. The Montreal Cognitive Assessment Test (MoCA) was administered control for global cognitive functioning. The effects of education and gender were also controlled in the analysis. The results of the present study suggested that: (1) The effect of age, favoring younger participants, was found in DT, vRT, mRT, and ATAVT tests. (2) The effect of global cognitive functioning was found in DT and ATAV tests. (3) The effect of the spatial mental transformation tests was found in DT, vRT (MRT only), and ATAVT (OPT only) tests. Taken together, these results suggest the specific contribution of spatial mental transformation skills in the execution of complex behaviors connected to the fitness to drive. Prospectively, the results of the present study relating spatial mental transformation skills and driving processes may be a valuable source of knowledge for researchers dealing with the relationship between cognitive resources and navigation aids.
Influencing Factors and Machine Learning-Based Prediction of Side Effects in Psychotherapy
Authors: Yao Lijun , Zhao Xudong , Xu Zhiwei , Chen Yang , Liu Liang , Feng Qiang , Chen Fazhan
Published: December 2020

Background: Side effects in psychotherapy are a common phenomenon, but due to insufficient understanding of the relevant predictors of side effects in psychotherapy, many psychotherapists or clinicians fail to identify and manage these side effects. The purpose of this study was to predict whether clients or patients would experience side effects in psychotherapy by machine learning and to analyze the related influencing factors.

Methods: A self-compiled “Psychotherapy Side Effects Questionnaire (PSEQ)” was delivered online by a WeChat official account. Three hundred and seventy participants were included in the cross-sectional analysis. Psychotherapy outcomes were classified as participants with side effects and without side effects. A number of features were selected to distinguish participants with different psychotherapy outcomes. Six machine learning-based algorithms were then chosen and trained by our dataset to build outcome prediction classifiers.

Results: Our study showed that: (1) the most common side effects were negative emotions in psychotherapy, such as anxiety, tension, sadness, and anger, etc. (24.6%, 91/370); (2) the mental state of the psychotherapist, as perceived by the participant during psychotherapy, was the most relevant feature to predict whether clients would experience side effects in psychotherapy; (3) a Random Forest-based machine learning classifier offered the best prediction performance of the psychotherapy outcomes, with an F1-score of 0.797 and an AUC value of 0.804. These numbers indicate a high prediction performance, which allowed our approach to be used in practice.

Conclusions: Our Random Forest-based machine learning classifier could accurately predict the possible outcome of a client in psychotherapy. Our study sheds light on the influencing factors of the side effects of psychotherapy and could help psychotherapists better predict the outcomes of psychotherapy.
Psychometric Evaluation of the Swedish Version of the Prolonged Grief Disorder-13 (PG-13) in a Bereaved Mixed Trauma Sample
Authors: Sveen Josefin , Bondjers Kristina , Heinsoo Julia , Arnberg Filip K.
Published: December 2020

Background: This study aimed to examine the psychometric properties of the Swedish PG-13 in a bereaved trauma exposed sample. A second aim was to examine the latent structure of prolonged grief using the PG-13.

Methods: The participants were adults (n = 123) taking part in an ongoing longitudinal study regarding the effects of potentially traumatic events. Participants had experienced a potentially traumatic event in the past 5 years and had reported a death of a significant other either as their primary traumatic event or in addition to another traumatic event. Assessment included self-report of prolonged grief, posttraumatic stress, and general psychological distress. Clinical interviews were used to assess depression, posttraumatic stress disorder, and disability level. The psychometric properties of the Swedish PG-13 were examined through reliability tests and assessment of associations with symptoms of posttraumatic stress, depression, general psychological distress, and disability level. Principal component analysis (PCA) and confirmatory factor analyses (CFA) were used to assess the latent structure.

Results: The internal consistency (Cronbach's α = 0.86) and test-retest (r = 0.86) reliability were good. PCA suggested a three-factor model as descriptive of the latent structure of the instrument. Therefore, the CFA used this model, as well as two models suggested in the literature. The three-factor model had the best fit to data. Support of concurrent validity of PG-13 was shown by moderate positive associations with measures of posttraumatic stress, depression, and general psychological distress.

Conclusions: The Swedish PG-13 demonstrated good psychometric properties, and its use in research and practice to assess prolonged grief was supported. The factor analyses provided stronger support for models with two or three factors, as compared with a unidimensional model of prolonged grief, with the three-factor model having the best fit.
Impacts of Stressful Life Events and Traumatic Experiences on Onset of Obsessive-Compulsive Disorder
Authors: Murayama Keitaro , Nakao Tomohiro , Ohno Aikana , Tsuruta Sae , Tomiyama Hirofumi , Hasuzawa Suguru , Mizobe Taro , Kato Kenta , Kanba Shigenobu
Published: December 2020

Not a few patients with obsessive-compulsive disorder (OCD) have experienced events that affected the onset. The onset of OCD is not limited to the original meaning of trauma; rather, traumatic experiences such as unexpected exposure to contaminants or various stressful life events often cause the onset of OCD. It would be useful to understand the experiences surrounding the onset, including stressful life events and traumatic experiences, for comprehension of the pathophysiology of OCD. In the present study, we investigated the onset conditions of 281 patients with OCD and compared clinical characteristics among groups with or without stressful life events including traumatic experiences. As a result, 172 (61.2%) participants had experienced various stressful life events, and 98 (34%) participants had had traumatic experiences before the onset. Furthermore, the participants who had had stressful life events showed more contamination/fear symptoms compared with those without such life events. Meanwhile, the patients who had had specific traumatic experiences showed a tendency toward hoarding obsessions. To comprehend the pathophysiology of OCD, it is important to understand the stressful life events that precede its onset.
Self-Harm, Suicidal Ideation, and Suicide Attempts in Chinese Adolescents Involved in Different Sub-types of Bullying: A Cross-Sectional Study
Authors: Peng Chang , Hu Wenzhu , Yuan Shanshan , Xiang Jingjing , Kang Chun , Wang Mengni , Rong Fajuan , Huang Yunxiang , Yu Yizhen
Published: December 2020

Background: Bullying tends to peak during adolescence, and it is an important risk factor of self-harm and suicide. However, research on the specific effect of different sub-types of bullying is limited.

Objective: The purpose of this study is to examine the associations between four common forms of bullying (verbal, physical, relational, and cyber) and self-harm, suicidal ideation (SI), and suicide attempts (SA).

Method: This was a cross-sectional study of a sample including 4,241 Chinese students (55.8% boys) aged 11 to 18 years. Bullying involvement, self-harm, SI, and SA were measured via The Juvenile Campus Violence Questionnaire (JCVQ). The association was examined through multinomial logistic regression analysis, adjusted for demographic characteristics and psychological distress.

Results: Bullying victimization and perpetration were reported by 18.0 and 10.7% of participants. The prevalence of self-harm, SI, and SA were 11.8, 11.8, and 7.1%, respectively. Relational bullying victimization and perpetration were significantly associated with SI only, SI plus self-harm, and SA. Physical bullying victimization and perpetration were risk factors of self-harm only and SA. Verbal victimization was significantly associated with SI only. Cyber perpetration was a risk factor of SA.

Conclusions: The findings highlight the different effects of sub-types of bullying on self-harm and suicidal risk. Anti-bullying intervention and suicide prevention efforts should be prior to adolescents who are involved in physical and relational bullying.
Interaction Between Smoking and Internet Gaming Disorder on Spontaneous Brain Activity
Authors: Qiu Xianxin , Han Xu , Wang Yao , Ding Weina , Sun Yawen , Zhou Yan , Lei Hao , Lin Fuchun
Published: December 2020

Converging lines of evidence indicates that smoking and internet gaming disorder (IGD) affect spontaneous brain activity, respectively. However, little is known about whether these two factors work together on the human brain. In this study, we investigated the interaction between smoking and IGD on local spontaneous brain activity using amplitude of low-frequency fluctuation (ALFF) based on resting-state fMRI (rs-fMRI). Forty-six cigarette smokers, 38 IGD individuals, 34 participants with both IGD and cigarette smoking (IGD-Smoking), and 60 healthy individuals involved in the study. Voxel-wise analysis of covariance of ALFF revealed that there were significant interactions between IGD by smoking in the right medial pre-frontal cortex (MPFC)/ventral striatum, bilateral cerebellar, and visual-related regions as well as the left temporal gyrus. In the right MPFC/ventral striatum and left temporal gyrus, ALFF in smoking group was significantly higher than healthy group while there were no significant ALFF differences between IGD-Smoking group and IGD group. While in the bilateral cerebellar and visual-related regions, ALFF in the smoking group was significantly lower than healthy group while ALFF in IGD-Smoking group did not show significant difference with IGD group. In addition, in the smoking group, ALFF of the right MPFC/ventral striatum was associated positively with anxiety and depression scores while the ALFF value in the smoking group had a trend toward negative correlation with SDS scores in the bilateral cerebellar and visual-related regions. The ALFF value in the smoking group was associated positively with anxiety score in the left temporal gyrus. These findings indicate that smoking and IGD interacted with each other in the human brain. Our results, in terms of spontaneous brain activity, may imply the fact that IGD people are more tended to get smoking. Moreover, it is possible to predict that smokers may be more easily to get internet addiction than healthy people.
The Effect of Subjective Perception of Work in Relation to Occupational and Demographic Factors on the Mental Health of Polish Nurses
Authors: Kowalczuk Krystyna , Krajewska-Kułak Elżbieta , Sobolewski Marek
Published: December 2020

Introduction: Nursing is considered one of the most stressful professions in the world. The high emotional burden associated with excessive workload in qualitative and quantitative terms, exposure to existing and emerging infectious diseases, daily confrontation with the suffering of individuals and their families and low social support leads to the development of numerous stress reactions among nurses, resulting in the development of anxiety, insomnia, social dysfunction and depression. Indeed, somatic and mental stress-related disease rates are higher among nurses than in the general population.

Aim: To determine the impact of subjective work characteristics on the mental health of nurses in relation to demographic and occupational factors.

Material and method: The research was carried out among 558 nurses working in hospitals in Podlaskie Voivodeship, and used the Subjective Work Evaluation Questionnaire (SWEQ) and Goldberg's GHQ-28 Questionnaire.

Results: As measured by SWEQ, and as self-assessed by means of the GHQ-28 questionnaire, overall stress negatively affects the nurses' health (R2 = 18.7%). Among the partial measures of the SWEQ questionnaire, work overload had strong and the lack of rewards, social relations and lack of support had weak negative effect on the overall mental health assessment of nurses (R2 = 19.2%). The responsibility measure was an exception that had a positive impact on the nurses' well-being. Among occupational and demographic factors, only higher education in relation to secondary education in interactions with the overall stress measure and unpleasant work conditions had a positive effect on the overall mental health self-assessment of nurses (R2 = 20.7%).

Conclusions: The results of our study provide a clear message to the hospital management that improving the work organization and atmosphere of nurses by reducing perceived work overload and increasing the responsibility of nurses can have a positive impact on their mental health. Encouraging nurses to improve their education can result not only in an obvious improvement in staff qualifications, but also in better resistance to stressors in the workplace and, consequently, in better staff well-being. Both measures can have a positive impact on the quality of care provided by nurses and on reducing staff turnover.
Factors Associated With Involuntary Psychiatric Hospitalization of Youths in China Based on a Nationally Representative Sample
Authors: Geng Feng , Jiang Feng , Conrad Rachel , Liu Tingfang , Liu Yuanli , Liu Huanzhong , Tang Yi-lang
Published: December 2020

Objective: This nationally representative sample investigates demographic, diagnostic and clinical features associated with both voluntary and involuntary psychiatric hospitalization among children and adolescents psychiatrically hospitalized in China.

Method: As part of an official national survey, 41 provincial tertiary psychiatric hospitals in China were selected. Data from 196 children and adolescents who were discharged from these psychiatric hospitals from March 19 to 31, 2019 were retrieved and analyzed.

Results: 1. Psychotic symptoms, depressive symptoms and self-injury/suicide were the most common reasons of admission. Girls were significantly likely to be admitted due to depressive symptoms, whereas boys were more likely to be admitted due to aggressive behaviors. 2. The overall rate of involuntary admission was 32.1% (N = 63). Compared to patients who were admitted voluntarily, those who were admitted involuntarily had lower GAF scores on admission, were older, were more likely to present with psychotic symptoms, manic symptoms or aggressive behavior as primary reason for admission, were less likely to present with depressive symptoms, had a significantly longer length of stay, were more likely to be diagnosed with schizophrenia and were less likely to be diagnosed as depressive disorder. 3. A logistic regression showed that depressive symptom as primary reason for admission was significantly associated with voluntary admission (OR = 0.159, p < 0.001), along with two other factors: age (p < 0.01) and a lower GAF score at admission (p < 0.001) were significantly associated with involuntary admission.

Conclusion: The rate of involuntary psychiatric hospitalization among children and adolescents is higher in China than in other regions. Developing more specific and more operational criteria to guide involuntary psychiatric admission for child and adolescent patients is of urgency and great importance to ensure appropriate treatment of these patients and protect their rights.
Motion Planning and Iterative Learning Control of a Modular Soft Robotic Snake
Authors: Luo Ming , Wan Zhenyu , Sun Yinan , Skorina Erik H. , Tao Weijia , Chen Fuchen , Gopalka Lakshay , Yang Hao , Onal Cagdas D.
Published: December 2020

Snake robotics is an important research topic with a wide range of applications, including inspection in confined spaces, search-and-rescue, and disaster response. Snake robots are well-suited to these applications because of their versatility and adaptability to unstructured and constrained environments. In this paper, we introduce a soft pneumatic robotic snake that can imitate the capabilities of biological snakes, its soft body can provide flexibility and adaptability to the environment. This paper combines soft mobile robot modeling, proprioceptive feedback control, and motion planning to pave the way for functional soft robotic snake autonomy. We propose a pressure-operated soft robotic snake with a high degree of modularity that makes use of customized embedded flexible curvature sensing. On this platform, we introduce the use of iterative learning control using feedback from the on-board curvature sensors to enable the snake to automatically correct its gait for superior locomotion. We also present a motion planning and trajectory tracking algorithm using an adaptive bounding box, which allows for efficient motion planning that still takes into account the kinematic state of the soft robotic snake. We test this algorithm experimentally, and demonstrate its performance in obstacle avoidance scenarios.
Cancer Persisters: How Playing Dead Helps Cancer Cells Survive Treatment
Authors: Karki Prashant , Orman Mehmet A.
Published: December 2020

Cells may occasionally have errors in their DNA, called mutations, which may lead to various diseases. Cancer cells are mutated cells that have lost their ability to control their growth. These cells divide rapidly and can spread to other parts of the body. Scientists take advantage of this trait of cancer cells to try to design various therapies to kill only cells that are dividing very quickly. But what would happen if cancer cells grew slowly or just stopped growing? Well, recent evidence shows that such cancer cells do exist. These cells, also referred to as cancer persisters, are generally non-growing cells that cannot be easily eliminated by traditional cancer therapies. In this article, we will describe what cancer persisters are and why we should make a significant effort to study them.
Origins of Relative Age Effects in Youth Football—A Nationwide Analysis
Authors: Romann Michael , Rüeger Eva , Hintermann Mirjam , Kern Raphael , Faude Oliver
Published: December 2020

Introduction: Relative age effects (RAEs) refer to the overrepresentation of players born earlier in the selection year compared to late-born players within the same age category. To date, the origins and mechanisms of RAEs are still unclear. To evaluate the development of RAEs in terms of age group and selection level, we analyzed data of all registered child and adolescent football players in Switzerland.

Methods: Age category, selection level, and birthdate from all licensed 101,991 Swiss child and youth football players assigned to a specific team [9,149 girls (9.0%) and 92,842 boys (91.0%); age range: 4.6–19.6 years] were analyzed. Additionally, out of 1,128 clubs, 54 clubs provided their documented waiting lists (1,224 players). Birthdate distributions were split by age category, sex, and birth quarter (Q1 = January to March, Q4 = October to December). RAEs were calculated using odds ratios (Q1 vs. Q4) with 95% confidence intervals (95% CI).

Results: We found small RAEs among U8 players (OR 1.44 [95% CI 1.31, 1.59]) and U10 (OR 1.24 [95% CI 1.16, 1.32]). The RAE was negligible in all other age categories, independent of gender. In children's football, 5,584 (71.3%) teams performed selections. In teams without selection, there were no obvious RAEs. However, teams with selections for the same age category showed small RAEs with an overrepresentation of Q1 athletes in the first team (OR = 1.29 [95% CI 1.24, 1.35]) and inverse RAEs with an underrepresentation of Q1 athletes in the last team (OR = 0.85 [95% CI 0.82, 0.89]). Only small RAEs were observed on the waiting lists for the U8 (OR = 1.48 [1.13, 1.95]).

Discussion and Conclusion: RAEs have a small, but consistent effect on participation in Swiss children's football at the grassroots level. Contrary to expectations, no inverse RAEs were found on the waiting lists. Nonetheless, first time coach selections seem to be the origin of RAEs. To protect young athletes from discrimination, RAE biases should be analyzed and eliminated at all stages of sport participation, selection, and dropout situations. Modifications to the organizational structure of sport and athlete development systems are recommended to prevent RAE-related discrimination in youth sports.
Case Report: A Malignant Liver and Thoracic Solitary Fibrous Tumor: A 10-Year Journey From the Brain to the Liver and the Spine
Authors: Mao Min , Zhou Lei , Huang Chaojun , Yan Xudong , Hu Shuo , Yin Huabin , Zhao Qinghua , Song Dianwen
Published: December 2020

Solitary fibrous tumors are rare neoplasms that originate from mesenchymal tissues and have been found to occur in any site, including the spine and liver. Although most of solitary fibrous tumors have benign features, only 10–20% are malignant and prone to metastasis. No previous reports have described the malignant and metastatic Solitary fibrous tumor arising in both of the liver and thoracic vertebrae. In this article, we present the case of a 60-year-old woman who underwent gross total resection of a meningeal tumor in 2007. She presented 10 years later with a thoracic vertebral mass that caused relentless pain and a lesion in the right lobe of liver. She underwent marginal excision of the T3 tumor with T2-4 pedicular screw fixation in March 2017, then right hemi-hepatectomy was performed to remove the liver lesion in June 2017. Both of the lesions were confirmed to be a metastatic and malignant tumor after surgery. The literature lacks randomized controlled trials and large studies that define the natural history of malignant solitary fibrous tumors and recommendations of precise management plan for the disease. However, the best choice for treatment is gross total resection, which probably provide the optimal treatment to achieve long-term disease-free survival.
Investigating Sentinel 2 Multispectral Imagery Efficiency in Describing Spectral Response of Vineyards Covered with Plastic Sheets
Authors: Borgogno-Mondino Enrico , de Palma Laura , Novello Vittorino
Published: December 2020

The protection of vineyards with overhead plastic covers is a technique largely applied in table grape growing. As with other crops, remote sensing of vegetation spectral reflectance is a useful tool for improving management even for table grape viticulture. The remote sensing of the spectral signals emitted by vegetation of covered vineyards is currently an open field of investigation, given the intrinsic nature of plastic sheets that can have a strong impact on the reflection from the underlying vegetation. Baring these premises in mind, the aim of the present work was to run preliminary tests on table grape vineyards covered with polyethylene sheets, using Copernicus Sentinel 2 (Level 2A product) free optical data, and compare their spectral response with that of similar uncovered vineyards to assess if a reliable spectral signal is detectable through the plastic cover. Vine phenology, air temperature and shoot growth, were monitored during the 2016 growing cycle. Twenty-four Copernicus Sentinel 2 (S2, Level 2A product) images were used to investigate if, in spite of plastic sheets, vine phenology can be similarly described with and without plastic covers. For this purpose, time series of S2 at-the-ground reflectance calibrated bands and correspondent normalized difference vegetation index (NDVI), modified soil-adjusted vegetation index, version two (MSAVI2) and normalized difference water index (NDWI) spectral indices were obtained and analyzed, comparing the responses of two covered vineyards with different plastic sheets in respect of two uncovered ones. Results demonstrated that no significant limitation (for both bands and spectral indices) was introduced by plastic sheets while monitoring spectral behavior of covered vineyards.
Comparison of Deep Learning Models and Various Text Pre-Processing Techniques for the Toxic Comments Classification
Authors: Maslej-Krešňáková Viera , Sarnovský Martin , Butka Peter , Machová Kristína
Published: December 2020

The emergence of anti-social behaviour in online environments presents a serious issue in today’s society. Automatic detection and identification of such behaviour are becoming increasingly important. Modern machine learning and natural language processing methods can provide effective tools to detect different types of anti-social behaviour from the pieces of text. In this work, we present a comparison of various deep learning models used to identify the toxic comments in the Internet discussions. Our main goal was to explore the effect of the data preparation on the model performance. As we worked with the assumption that the use of traditional pre-processing methods may lead to the loss of characteristic traits, specific for toxic content, we compared several popular deep learning and transformer language models. We aimed to analyze the influence of different pre-processing techniques and text representations including standard TF-IDF, pre-trained word embeddings and also explored currently popular transformer models. Experiments were performed on the dataset from the Kaggle Toxic Comment Classification competition, and the best performing model was compared with the similar approaches using standard metrics used in data analysis.
Intensity Measure Based on a Smooth Inelastic Peak Period for a More Effective Incremental Dynamic Analysis
Authors: Vielma Juan Carlos , Porcu Maria Cristina , López Nelson
Published: December 2020

The Incremental Dynamic Analysis (IDA) assesses the global collapse capacity of a structure by plotting its maximum inelastic response, obtained through a non-linear time-history analysis, versus the scaled intensity of different input earthquakes. The seismic intensity is often measured through the spectral acceleration at the fundamental elastic period. However, this can produce highly variable results. An alternative method is presented in this paper that relies on the elongated period, calculated either from the Fourier spectrum of the acceleration at a target building point (inelastic peak period) or from a smooth Fourier spectrum (inelastic smooth peak period). By referring to a reference reinforced concrete building and to a set of 10 spectrum-consistent earthquakes, the paper presents the results of a wide investigation. First, the variation in the elongated period as a function of the seismic intensity is discussed. Then, the effectiveness of the proposed method is assessed by comparing the IDA curves to those obtained through the elastic period or through approximate values of the elongated period given in the literature. The results show that the alternative IDA procedure generates curves with less-dispersed collapse thresholds. A statistical analysis shows significant improvements in the results when the inelastic smooth peak period is adopted.
Performance Analysis of Multi-Spindle Drilling of Al2024 with TiN and TiCN Coated Drills Using Experimental and Artificial Neural Networks Technique
Authors: Aamir Muhammad , Tolouei-Rad Majid , Vafadar Ana , Raja Muhammad Nouman Amjad , Giasin Khaled
Published: December 2020

Multi-spindle drilling simultaneously produces multiple holes to save time and increase productivity. The assessment of hole quality is important in any drilling process and is influenced by characteristics of the cutting tool, drilling parameters and machine capacity. This study investigates the drilling performance of uncoated carbide, and coated carbide (TiN and TiCN) drills when machining Al2024 aluminium alloy. Thrust force and characteristics of hole quality, such as the presence of burrs and surface roughness, were evaluated. The results show that the uncoated carbide drills performed better than the TiN and TiCN coated tools at low spindle speeds, while TiCN coated drills produced better hole quality at higher spindle speeds. The TiN coated drills gave the highest thrust force and poorest hole quality when compared with the uncoated carbide and TiCN coated carbide drills. Additionally, a multi-layer perceptron neural network model was developed, which could be useful for industries and manufacturing engineers for predicting the surface roughness in multi-hole simultaneous drilling processes.