bluuebunny/crossref_metadata_2025 huggingface dataset:
Stigma processes, psychological distress, and attitudes toward seeking treatment among pedohebephilic people
Authors: Jahnke Sara , McPhail Ian V. , Antfolk Jan
Published: October 2024

While stigma theories predict that stigma relates to negative attitudes toward seeking help, previous studies found mixed results among pedohebephilic individuals. We tested whether different stigma processes (i.e., general anticipated stigma, anticipation of negative therapist behavior upon disclosure, and internalized stigma), psychological distress, previous treatment experiences, and knowledge about psychotherapy can clarify attitudes toward seeking professional psychological help for this population. We conducted a pre-registered, online survey of English-speaking pedohebephilic individuals (N = 283, 88% male). Expected links between variables of interest and attitudes toward seeking treatment were assessed via structural equation modeling. After modification, the final model showed acceptable fit to the data, χ2 = 2170.61, df = 1462, p < .001, CFI = .905, RMSEA = .04, [.04,.05]. Internalized stigma predicted more positive attitudes toward seeking treatment. Lower anticipation of negative therapist behavior upon disclosure and higher knowledge about psychotherapy were also significant predictors of positive attitudes toward seeking treatment. General anticipated stigma did not predict attitudes toward seeking treatment. Our results suggest a complex association between different stigma processes and treatment-seeking, which differs from associations found for mental illness stigma. Specificity in our understanding of the components of stigma and how they interact with attitudes toward seeking treatment is required to tailor clinical work as well as messages around treatment services.
CD70 is a potential prognostic marker and significantly regulates cellular function in diffuse large B-cell lymphoma
Authors: Liu Kang , Yang Qiuyue , Liu Ping , Zhu Kaibo , Zou Min , Zhu Qiang , Yi Ping , Fang Kun , Luo Zimian
Published: October 2024

Extensive research has demonstrated that dysregulation of costimulatory molecule expression plays a pivotal role in cancer biology. However, the impact of intratumoral CD70 on the initiation, progression, and immune response in diffuse large B-cell lymphoma (DLBCL) remains poorly understood. This study aims to elucidate the clinical significance of CD70 in DLBCL diagnosis and prognosis, as well as its relationship with the immune microenvironment. We first analyzed CD70 expression across various cancers, including DLBCL, using multiple online databases (TIMER, GEPIA, GENT2, TNMPlot, GSCA, and GEO). We then evaluated the clinical correlations and prognostic value of CD70 in DLBCL. Additionally, we investigated the functional role of CD70 in DLBCL cells. Genomic alterations of CD70 were analyzed using the cBioPortal online tool. Co-expression network analysis was performed to assess the biological functions associated with CD70. Furthermore, we utilized TIMER2.0 to examine the correlation between CD70 expression and immune cell infiltration. Our results revealed that CD70 expression was significantly upregulated in DLBCL tissues compared to matched normal tissues, and high CD70 expression was associated with poor clinical outcomes in DLBCL patients. In vitro experiments demonstrated that CD70 inhibition promotes apoptosis and induces G1 phase arrest in DLBCL cells. Genomic alteration analysis showed that patients with CD70 alterations exhibited worse overall survival compared to those without such alterations. Co-expression and functional enrichment analyses indicated that CD70 is functionally related to tumor necrosis factor receptor binding and the NF-κB signaling pathway. Moreover, we found that CD70 expression levels were negatively correlated with B cell and NK cell infiltration in DLBCL. In conclusion, this study suggests that CD70 is a potential diagnostic and therapeutic biomarker for DLBCL. Our findings provide valuable insights for the development of novel therapeutic strategies targeting CD70 in DLBCL treatment.
Can deep learning identify humans by automatically constructing a database with dental panoramic radiographs?
Authors: Choi Hye-Ran , Siadari Thomhert Suprapto , Ko Dong-Yub , Kim Jo-Eun , Huh Kyung-Hoe , Yi Won-Jin , Lee Sam-Sun , Heo Min-Suk
Published: October 2024

The aim of this study was to propose a novel method to identify individuals by recognizing dentition change, along with human identification process using deep learning. Recent and past images of adults aged 20–49 years with more than two dental panoramic radiographs (DPRs) were assumed as postmortem (PM) and antemortem (AM) images, respectively. The dataset contained 1,029 paired PM-AM DPRs from 2000 to 2020. After constructing a database of AM dentition, the degree of similarity was calculated and sorted in descending order. The matched rank of AM identical to an unknown PM was measured by extracting candidate groups (CGs). The percentage of rank was calculated as the success rate, and similarity scores were compared based on imaging time intervals. The matched AM images were ranked in the CG with success rates of 83.2%, 72.1%, and 59.4% in the imaging time interval for extracting the top 20.0%, 10.0%, and 5.0%, respectively. The success rates depended on sex, and were higher for women than for men: the success rates for the extraction of the top 20.0%, 10.0%, and 5.0% were 97.2%, 81.1%, and 66.5%, respectively, for women and 71.3%, 64.0%, and 52.0%, respectively, for men. The similarity score differed significantly between groups based on the imaging time interval of 17.7 years. This study showed outstanding performance of convolutional neural network using dental panoramic radiographs in effectively reducing the size of AM CG in identifying humans.
Navigating the cancer care continuum: A comparative study of Black and White breast cancer patients
Authors: Lee Min K. , Levine Naomi T-T. , Hayes Lisa R. , Shields Cleveland G. , Yih Yuehwern
Published: October 2024

Despite improvements in early detection and therapeutic interventions, the mortality rate for Black breast cancer patients is still significantly higher than that of White breast cancer patients. This study seeks to understand differences in the patient experience that lead to this disparity. Semi-structured interviews were conducted to understand the breast cancer treatment process and patient experiences. This study collected health services and timeline data from medical records. Based on these two data sources, the patient’s journey in breast cancer treatment was mapped and a thematic analysis was conducted to identify challenges and barriers in the process. The cancer care continuum consists of four stages—diagnosis, surgery, chemotherapy/radiation, and follow-up care. The themes contributing to patient experiences and challenges were identified and compared in each stage for both Black and White patients. Both Black and White participants faced challenges related to financial constraints, treatment changes, lack of autonomy, and insufficient emotional support. However, Black participants additionally faced significant barriers in terms of cultural concordance, effective patient-provider communication, and delay in diagnosis. This study highlights the importance of incorporating effective provider-patient communication, navigation, and emotional support, especially for Black breast cancer patients throughout the cancer care continuum to address healthcare disparities.
Prevalence and determinants of prehospital delay among stroke patients in mainland China: A systematic review and meta-analysis of the study protocol
Authors: Deng Hui , Wang Xiangming , Yin Li , Li Xianzhi , Zhang Yuehui
Published: October 2024

Background

Prehospital delay is one of the most serious problems in the treatment of stroke patients. In China, although hospitals at all levels have promoted the construction of stroke centers, pre-hospital delays are still very common. As the primary cause of death and disability, stroke not only brings great harm to patients themselves, but also brings a heavy burden on social progress and economic development, it is important to understand the prevalence and determinants of prehospital delay among stroke patients. Therefore, this review aims to determine the pooled prevalence and determinants of prehospital delay in mainland China.

Methods

A systematic review of eligible articles will be conducted using preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines. A comprehensive literature search will be conducted in PubMed, Embase, Cochrane, web of science, China National Knowledge Infrastructure (CNKI), Wanfang, Weipu (VIP) and Chinese Biomedicine Iiterature databas (CBM) databases. The quality of the articles included in the review will be evaluated using the Newcastle-Ottawa Scale (NOS). The pooled prevalence of prehospital delay, and odds ratio and their 95% confidence intervals for relevant influencing factors, will be calculated using RevMan 5.3 software. The existence of heterogeneity among studies will be assessed by computing p-values of Higgins’s I2 test statistics and Cochran’s Q-statistics. Sensitivity analysis and subgroup analysis will be conducted based on study quality to investigate the possible sources of heterogeneity. Publication bias will be evaluated by funnel chart and by Egger’s regression test. This review protocol has been registered PROSPERO (CRD42023484580).

Discussion

By collecting and summarizing information on prehospital delay among stroke patients can be a step towards a better understanding of the prevalence of prehospital delay among stroke patients in mainland China and how the associated factors influence the prevalence of prehospital delay. Therefore, a rapid, accurate diagnosis Stroke, timely pre-hospital first aid, the treatment process forward, for the patient It has great significance. This summarized finding at the national level will provide new clues for intervention to reduce the rate of pre-hospital delay of stroke patients, and is expected to further improve the treatment effect of stroke patients.
S3260 An Interesting Case of Lymphocytic Esophagitis In Association With Pityriasis LichenoidesChronica and Rheumatoid Arthritis
Authors: Menon Raakhi , Abdul-Baki Kian , Aburayyan Kanana , Thaker Harshwardhan , Al-Saadi Yamam
Published: October 2024

Introduction:

Lymphocytic esophagitis (LyE) is a rare esophageal disorder of unknown etiology, characterized by dense peripapillary lymphocytes without neutrophils or eosinophils, and spongiosis. Patients typically present with symptoms such as dysphagia or chest pain. Here, we describe a notable case of lymphocytic esophagitis in a patient who presented with food impaction.

Case Description/Methods:

A 53-year-old woman with a history of pityriasis lichenoideschronica and rheumatoid arthritis reported chronic dysphagia and sought emergency care for food impaction. A subsequent upper endoscopy revealed a long submucosal tear in the upper esophagus during intubation (see Figure 1A), leading to the procedure's cessation. A follow-up upper endoscopy 9 weeks later, employing an ultra-slim scope, identified severe stenosis in the upper esophagus (see Figure 1B). Dilation was performed using a Savary dilator. Examination of the esophageal lining revealed edema, rings, and furrows. Proximal and distal esophageal biopsies were obtained, indicating a marked increase in intraepithelial lymphocytes, with an absence of eosinophils or neutrophils. The squamous epithelium exhibited evidence of spongiosis and necrotic keratinocytes, consistent with a diagnosis of lymphocytic esophagitis. The patient continued omeprazole 40 mg twice daily and started budesonide at 1 mg twice daily. A repeat upper endoscopy with esophageal biopsies demonstrated a significant improvement in lymphocytic infiltration (see Figure 2A-B).

Discussion:

LyE typically manifests in females during their 5th-6th decades, presenting a notable contrast to eosinophilic esophagitis (EOE), which predominantly affects males in their 2nd-3rd decades. However, the endoscopic appearance of LyE often mirrors that of EOE. Studies suggest potential associations between LyE and Crohn's disease in children, as well as primary esophageal dysmotility in adults. Notably, our patient has a history of rheumatoid arthritis, a correlation observed in 2 other cases in the literature. While limited literature exists on pityriasis lichenoideschronica with esophageal involvement, specifically presenting as LyE, this singular case underscores the interconnection of these 2 disease processes. These observations raise the possibility of an autoimmune etiology. There is no consensus on the lymphocyte count threshold for diagnosis, a challenge compounded by the rarity of the disease, leading to a lack of definitive guidelines for optimal management.

JOURNAL/ajgast/04.03/00000434-202410001-03261/figure1/v/2025-02-20T041334Z/r/image-tiff
Fatigue analysis on flax-epoxy composites: insights and implications
Authors: Pagliaro Andrea , Cagnetta Lorenzo
Published: October 2024

This study investigates the performance of flax fiber and epoxy resin composites, focusing on fatigue testing, which is scarcely reported in the literature. Fatigue behavior is evaluated under full reverse bending loading conditions: R = −1. Apart of the definition of the classic S-N curve, the analysis deeply investigated the evolution of the hysteresis leaf generated during each cycle over the entire fatigue life. This approach allows evaluating interesting parameters such as the evolution of the loss factor and the apparent modulus over life, being these informations fundamental for practical application of natural-fiber composites in engineering applications.
Characterization of woven composite material under multiaxial loading regimes using FE-based stereocorrelation
Authors: Zaplatić Andrija , Tomičević Zvonimir , Hild François
Published: October 2024

In this paper, woven glass fiber composite samples were subjected to three different cyclic loading histories (i.e., tensile, shear and combined loading at 45° via the Modified Arcan Fixture. During the experiments, the samples were monitored by a stereovision system. Finite Element based stereocorrelation was used to measure the displacement and strain fields. The analysis of the experiments revealed different damage mechanisms. Furthermore, for the 45° experiment, the highest strain levels were reached, whereas for the tensile test, the highest stress levels were achieved.
Two significant moments in the history of Kaaps
Authors: van Rensburg Christo
Published: October 2024

Two matters are considered in this paper. (i) The identification of the first version of Kaaps, the progenitor of Afrikaans. The earliest version of Kaaps was recorded during the first period of the history of Afrikaans - the period prior to 1652. This period commences with the first visits to the Cape by Dutch mariners. The written records of Kaaps dating from that period are older than any other manifestation of forms in Afrikaans. Some of these early words are currently still in use among speakers of Kaaps, while others have been incorporated into Standard Afrikaans, or appear in dictionaries and the AWS (Afrikaanse Woordelys en Spelreels- Wordlist and Spelling rules for Afrikaans). Some even continue to survive in the spoken Afrikaans of a number of regional dialects. Reference is also made in this chapter to how Kaaps eventually developed and played an important role in the shaping of other varieties of Afrikaans. (ii) The circumstances leading to the incorporation of elements of other varieties into the core description of Afrikaans. In describing Afrikaans, language historians usually ask where particular words and constructions come from. But the question how is actually of greater value when investigating the development of Afrikaans. Ek (I) is a word in Kaaps which was, over time, absorbed into general use in Afrikaans. An analysis of how this process took place reveals that the "how" questions are of greater importance in the history of the language than the "when" and "where" questions. The true story of Afrikaans is a socio-historical one. Destigmatization, and the circumstances leading to changing norms, are evoked by the "how" questions.
The Conceptual Evolution in Linguistics: implications for the study of Kaaps
Authors: Dyers Charlyn
Published: October 2024

As an academic discipline, Linguistics - the scientific study of language - is associated with a range of concepts. Students of Linguistics are traditionally introduced to these concepts in their first year of study, and everything that follows builds on knowledge of these concepts. But language, as Blommaert (2011) notes, is the most visible sign of social change. Currently, much critical thinking is said to be philosophical outflows of a late or post-modern era, characterized by an intensification of three characteristics that have been part of human history for some time: globalization, migration and the dominant position of English, accompanied by the growth of new hybrid languages in urban spaces. In terms of the ongoing vitality of other languages and the influence of a number of dominant language ideologies (Weber and Horner 2012), these three characteristics have sparked discourses of endangerment, revitalization, commodification and carnivalisation (Duchene en Heller, 2007; Heller, 2010). At the same time, there has been a steady evolution in our understanding of many linguistic concepts, particularly those emanating from particular language ideologies and hierarchical political powers. This paper addresses this issue and its implications for the study and treatment of the colloquial variety of Afrikaans known as Kaaps. The contents of the paper have been slightly modified from the original Afrikaans version which appeared in Kaaps in Fokus.
Analisis Kinematik Dan Karakterisasi Massa Batuan Menggunakan Metode Kuantifikasi Geological Strength Index (GSI) Pada Lereng Tambang Batubara PT. Mifa Bersaudara
Authors: Wusqa Urwatul , Rezky Danu Mirza
Published: October 2024

Karakterisasi dilakukan untuk mempelajari dan mengelompokkan massa batuan berdasarkan keterdapatan struktur, pelapukan serta faktor lain yang dapat mempengaruhi kondisi massa batuan, Kondisi massa batuan terus berubah seiring berjalannya waktu dan pergerakan kemajuan penambangan. Oleh karena itu, Pembaruan data mengenai kekuatan massa batuan diperlukan sebagai adjusment parameter analsis kestabilan lereng guna memastikan rekomendasi geoteknik yang dikeluarkan sesuai dengan kondisi aktual di lapangan. Metode karakterisasi massa batuan yang digunakan adalah kuantifikasi GSI yang diperbarui oleh Sonmez dan Ulusay (1999), dengan menggunakan dua parameter yaitu struktur rating dan surface condition rating. Metode kuantifikasi GSI dipakai untuk mengurangi bias dari penentuan GSI secara kualitatif. Analisis kinematik dilakukan menggunakan proyeksi stereografis menggunakan software Dips untuk menentukan potensi longsoran apa yang mungkin terjadi sesuai hasil geotechnical mapping dilapangan. Dari sembilan lereng yang di mapping, teridentifikasi tiga jenis longsoran, yakni longsoran toppling, baji, dan bidang. Hasil pengelompokkan massa batuan terhadap sembilan lereng menunjukkan bahwa kelas massa batuan sebagian besar berada pada tingkat baik dan sedang. Hasil dari GSI akan digunakan sebagai parameter masukan kekuatan massa batuan pada saat analisis dengan output rekomendasi geometri lereng tambang sesuai dengan lokasi pengukuran. Penjelasan tentang pemilihan metode kuantifikasi GSI serta tahapan penentuan nilai GSI dan analisis kinematic dibahas lebih lanjut pada paper ini.
Analisis Perbandingan Transportasi Sedimen Menggunakan Metode Granulometri pada Sungai Damar Section Hulu dan Hilir Kabupaten Kendal
Authors: Wicitra Annisa Puspa , Taufiqi Khoirul , Rianawati Ranita Fitri , Jayanti Anita Galih Ringga
Published: October 2024

Granulometri merupakan analisis untuk mengidentifikasi ukuran butiran dan hubungannya dengan proses sedimentasi. Penelitian ini dilakukan di aliran Sungai Damar, Kabupaten Kendal, dengan dua titik lokasi pengambilan sampel, yaitu di hulu (Kecamatan Sukorejo) dan hilir (Kecamatan Weleri). Keterdapatan endapan sedimen material vulkanik, material batuan karbonat pada Formasi Kerek, dan aluvial yang terdapat di sepanjang aliran Sungai Damar menjadi cukup menarik untuk mengetahui  proses transportasi sedimen berdasarkan ukuran butiran yang tertransportasi. Metode yang digunakan adalah analisis granulometri cara grafis, untuk mendapatkan nilai sortasi, Skewness, dan Kurtosis. Hasil penelitian menunjukkan aliran Sungai Damar melalui beberapa formasi, seperti Formasi Kaligetas, Formasi Kerek, Formasi Damar, dan Endapan Aluvium. Dari hasil perhitungan didapatkan nilai sortasi kedua sampel dengan sortasi sangat baik, nilai Skewness kedua sampel termasuk ke dalam strongly coarse skewed, sedangkan dari hasil Kurtosis pada bagian hulu termasuk platykurtic, sedangkan bagian hilir termasuk very leptokurtic. Dari hasil transportasi tersebut menunjukkan adanya faktor kontrol lain, seperti kondisi geologi, geomorfologi, dan hidrodinamika mempengaruhi proses transportasi sedimen di Sungai Damar. Formasi geologi pada bagian hulu tingkat erosi lebih tahan daripada bagian hilir. Geomorfologi mencakup bentuklahan struktural berbukit terjal di hulu dan landai di hilir. Hidrodinamika dengan pola aliran dendritik dan cabang sungai pendek yang mempengaruhi transportasi sedimen di wilayah tersebut. Pada bagian hulu, dominan traksi karena kemiringan lereng yang curam, sedangkan dominan saltasi di hilir karena kemiringan lereng yang lebih landai.
Iran’s Asymmetric Interventionism: The Analysis of the Proxy Warfare Strategy Since 2011
Authors: Ahmadzada Kanan
Published: October 2024

The aim of this article is to examine and evaluate Iran’s indirect military intervention through the utilization of local non-state actors in the conflict zones of the Middle East. Particular attention was paid to the gray zone confrontation between Iran and the U.S.-led alliance after the outbreak of the Arab Spring in 2011. What are the characteristics of Iran’s proxy warfare (PW) dynamics, and to what extent has this strategy been effective in attaining its objectives? In this regard, PW theory has been chosen as the main theoretical framework, with its most recent advances in the literature. The paper argues that Iran’s adoption of PW strategy ultimately aims a) to reduce perceived threats originating from the U.S.-led alliance, b) deter potential military interventions on its soil, and c) render the U.S. presence in the Middle East burdensome with the ultimate aim of its withdrawal from the region over the long term. Moreover, it contends that although it comes at a cost and poses significant risks for Tehran, this strategy demonstrated effectiveness within the context of Iran’s prioritized principles. A primary contributing factor to Iran’s effective implementation of this strategy lies in its partnership style with its clients. Indeed, besides their strategic objectives, the main factor ensuring the resilience of the proxy alliance is the ideological affinity between the Iranian regime and the client forces.
A comprehensive survey of artificial intelligence adoption in European laboratory medicine: current utilization and prospects
Authors: Cadamuro Janne , Carobene Anna , Cabitza Federico , Debeljak Zeljko , De Bruyne Sander , van Doorn William , Johannes Elias , Frans Glynis , Özdemir Habib , Martin Perez Salomon , Rajdl Daniel , Tolios Alexander , Padoan Andrea
Published: October 2024

Background

As the healthcare sector evolves, Artificial Intelligence’s (AI’s) potential to enhance laboratory medicine is increasingly recognized. However, the adoption rates and attitudes towards AI across European laboratories have not been comprehensively analyzed. This study aims to fill this gap by surveying European laboratory professionals to assess their current use of AI, the digital infrastructure available, and their attitudes towards future implementations.

Methods

We conducted a methodical survey during October 2023, distributed via EFLM mailing lists. The survey explored six key areas: general characteristics, digital equipment, access to health data, data management, AI advancements, and personal perspectives. We analyzed responses to quantify AI integration and identify barriers to its adoption.

Results

From 426 initial responses, 195 were considered after excluding incomplete and non-European entries. The findings revealed limited AI engagement, with significant gaps in necessary digital infrastructure and training. Only 25.6 % of laboratories reported ongoing AI projects. Major barriers included inadequate digital tools, restricted access to comprehensive data, and a lack of AI-related skills among personnel. Notably, a substantial interest in AI training was expressed, indicating a demand for educational initiatives.

Conclusions

Despite the recognized potential of AI to revolutionize laboratory medicine by enhancing diagnostic accuracy and efficiency, European laboratories face substantial challenges. This survey highlights a critical need for strategic investments in educational programs and infrastructure improvements to support AI integration in laboratory medicine across Europe. Future efforts should focus on enhancing data accessibility, upgrading technological tools, and expanding AI training and literacy among professionals. In response, our working group plans to develop and make available online training materials to meet this growing educational demand.
Causal inference with textual data: A quasi-experimental design assessing the association between author metadata and acceptance among ICLR submissions from 2017 to 2022
Authors: Chen Chang , Zhang Jiayao , Ye Ting , Roth Dan , Zhang Bo
Published: October 2024

Many recent studies have probed status bias in the peer-review process of academic journals and conferences. In this article, we investigated the association between author metadata and area chairs’ final decisions (Accept/Reject) using our compiled database of 5,313 borderline submissions to the International Conference on Learning Representations from 2017 to 2022 under a matched observational study framework. We carefully defined elements in a cause-and-effect analysis, including the treatment and its timing, pre-treatment variables, potential outcomes (POs) and causal null hypothesis of interest, all in the context of study units being textual data and under Neyman and Rubin’s PO framework. We found some weak evidence that author metadata was associated with articles’ final decisions. We also found that, under an additional stability assumption, borderline articles from high-ranking institutions (top-30% or top-20%) were less favored by area chairs compared to their matched counterparts. The results were consistent in two different matched designs (odds ratio = 0.82 [95% confidence interval (CI): 0.67 to 1.00] in a first design and 0.83 [95% CI: 0.64 to 1.07] in a strengthened design) and most pronounced in the subgroup of articles with low ratings. We discussed how to interpret these results in the context of multiple interactions between a study unit and different agents (reviewers and area chairs) in the peer-review system.
Mapping evolution and trends of cell membrane-coated nanoparticles: A bibliometric analysis and scoping review
Authors: Li Chong , Hu Jing , He Jing , He Chengqi
Published: October 2024

The limitations of traditional drug therapy have driven the creation and development of novel cell membrane-coated nanoparticle (CMNP) platforms. Since the introduction of the CMNP concept and method in 2011, an increasing number of studies focusing on this field have been widely conducted. Despite the growing body of literature, comprehensive bibliometric analysis in this field is still lacking. This study conducted a bibliometric analysis of CMNP-related publications sourced from the Web of Science Core Collection database, covering the period from January 1, 2011, to December 31, 2023. The analysis included co-authorships, co-citations, and co-occurrences of countries, institutions, authors, references, and keywords. Visualized tools such as Citespace, VOSviewer, and R Package Bibliometrix were employed to present the data. A total of 780 studies were included, with China contributing the highest number of publications (75.64%, n = 590). The number of annual publications increased consistently from 2011 to 2023, indicating a growing global interest in the CMNP field. Prof. Liangfang Zhang from the United States is recognized as the founder and leading figure in this area. The top three academic journals in this field, based on publication volume, are ACS Nano (32 publications, IF 2022 = 17.1), ACS Applied Materials Interfaces (32 publications, IF 2022 = 9.5), and Advanced Functional Materials (31 publications, IF 2022 = 19) among 185 scholarly journals. Reference and keyword analysis revealed that erythrocytes and macrophage membranes are significant research hotspots. The primary diseases targeted by CMNP research are cancer and pulmonary inflammation. In addition, CMNPs are frequently studied in conjunction with photothermal and photodynamic therapy. Furthermore, this study also summarized the timelines for various cell membrane coating methods and the three-step preparation process for CMNP. This comprehensive bibliometric analysis provides valuable insights to guide future research in the CMNP field, highlighting the importance of clinical application. Research on cell membrane-coated nanomaterials, particularly those related to cancer and pulmonary inflammation, is expected to remain a focal point. In addition, there is a need for the further development of other potential cell membrane-coated nanomaterials. This bibliometric analysis serves as a resource for researchers to quickly and comprehensively understand the current hotspots and emerging frontiers in this field.
ПРИМЕНЕНИЕ ТРАНСФОРМЕРА ДЛЯ КОДИРОВАНИЯ СОСТОЯНИЙ В ОБУЧЕНИИ С ПОДКРЕПЛЕНИЕМ
Authors: Д.А. КОЗЛОВ
Published: October 2024

Исследуется применение архитектуры трансформера для кодирования состояний в алгоритмах обучения с подкреплением. Представлен новый подход, который интегрирует трансформеры с существующими методами, такими как SAC (Soft Actor-Critic), для улучшения их производительности и обобщающей способности. Результаты экспериментальных исследований показывают, что предложенный подход может улучшить обучение в сложных задачах приобретения навыков передвижения в трёхмерном пространстве.

This article explores the application of the transformer architecture for encoding states in reinforcement learning algorithms. A new approach is presented, which integrates transformers with existing methods, such as Soft Actor-Critic (SAC), to enhance their performance and generalization ability. The results of experimental studies show that the proposed approach can improve learning in complex tasks of acquiring movement skills in a three-dimensional space.
МОДЕЛЬ ОПТИЧЕСКОГО КОММУТАТОРА C ЧАСТОТНО-ВРЕМЕННЫМ РАЗДЕЛЕНИЕМ СИГНАЛОВ И ДЕЦЕНТРАЛИЗОВАННЫМ УПРАВЛЕНИЕМ
Authors: К.А. ВЫТОВТОВ , Е.А. БАРАБАНОВА , М.Г. ИВАНОВ , Г.К. ВЫТОВТОВ
Published: October 2024

Предложена принципиально новая модель оптического коммутатора с децентрализованным управлением. Преимуществами предлагаемого коммутатора являются отсутствие оптоэлектронного преобразования информационного сигнала и возможность построения масштабируемых схем малой сложности. Схема коммутатора включает в себя следующие основные элементы: электрически управляемые ключи на основе ниобата лития, фильтры Брэгга, оптические вентили, фокусирующие системы, управляющую линзовую систему, локальную систему формирования управляющих сигналов. Проведённый расчёт оптических устройств коммутатора показал возможность его реализации и функционирования в диапазонах 1310-1460 нм для передачи управляющих сигналов и 1550 нм - для информационного сигнала, обеспечивающего взаимодействие устройств центров обработки данных.

A fundamentally new model of an optical switch with decentralized control is proposed. The advantages of the proposed switch are the absence of optoelectronic conversion of the information signal and the possibility of constructing scalable circuits of low complexity. The switch circuit includes the following main elements: electrically controlled switch elements based on lithium niobate, Bragg filters, optical valves, focusing systems, a control lens system, and a local system for generating control signals. The calculation of the optical devices of the switch shows the possibility of its implementation and operation in the range of 1310-1460 nm for transmitting control signals and 1550 nm for the information signal to ensure interaction between data center devices.
СЕЙСМИЧЕСКИЙ И ГИДРОГЕОЛОГИЧЕСКИЙ МОНИТОРИНГ ПАРАМЕТРОВ МАССОВОГО ВЗРЫВА В ЛЕБЕДИНСКОМ КАРЬЕРЕ КУРСКОЙ МАГНИТНОЙ АНОМАЛИИ
Authors: Э.М. ГОРБУНОВА , С.М. ПЕТУХОВА , А.Г. ИВАНОВ
Published: October 2024

Представлен анализ результатов сейсмической и гидрогеологической регистрации массового взрыва, проведенного 22.09.2021 г. в Лебединском карьере Курской магнитной аномалии. При взрыве четырех групп блоков определены значения максимальной скорости смещения грунта в пяти пунктах наблюдений, расположенных на эпицентральных расстояниях 1.7 - 4.9 км, и амплитуды гидрогеологических откликов обводненной надрудной толщи в двух наблюдательных скважинах. Основные параметры взрывов, оказавшие наибольшее сейсмическое воздействие на массив, использованы для расчета максимальной скорости колебаний в волне по установленной ранее зависимости. Расхождения между зарегистрированными и расчетными параметрами отмечены в ближней зоне взрыва первой группы блоков, разрабатываемых в рудно-кристаллическом массиве на приведенных расстояниях 106- 198 м/кг1/3. При осуществлении взрывов в осадочных отложениях на приведенных расстояниях 405 - 512 м/кг1/3 прослежено отличие в формировании волнового поля. Полученные данные могут быть привлечены для контроля технологии буровзрывных работ.

The authors analyze seismic and hydrogeological data recorded after a large-scale blast on 22 September 2021 in Lebedinsky open pit mine, Kursk Magnetic Anomaly. In blasting of four groups of blocks, the maximum values of PPV are determined at five observation points arranged at the epicentral distances of 1.7-4.9 km, as well as the amplitudes of the hydrogeological response are assessed in two observation wells in overlying rock mass. The main parameters of the blast-induced seismic effect are used to calculate maximum PPV from the earlier found relation. The divergence of the recorded and theoretical data is observed in the near field of the blast in the first group of blocks, at the reduced distances of 106-198 m/kg1/3. In blasting in sedimentary rocks at the reduced distances of 405-512 m/kg1/3, the difference in the wavefield is observed. The research findings can be used in drilling-and-blasting control.
ДЕФОРМИРОВАНИЕ СКАЛЬНЫХ ВСКРЫШНЫХ ПОРОД НА ДАМБАХ И ОТВАЛАХ ПРИ ЭКСПЛУАТАЦИИ ГОРНОТРАНСПОРТНОГО ОБОРУДОВАНИЯ
Authors: В.А. БАБЕЛЛО , М.В. ЛИЗУНКИН
Published: October 2024

Установлены параметры сжимаемости скальных пород нарушенного сложения для прогноза осадки горнотранспортного оборудования и устойчивости дамбы. Экспериментальные исследования проведены на крупногабаритном стенде штамповым методом при различных значениях плотности скальной вскрышной породы и нормального давления. Представлен способ оценки деформируемости скальных вскрышных пород с помощью пластины и геодезической рейки. Полученные результаты использовались для оценки возможности прохождения горнотранспортного оборудования при возведении дамбы и расчета ее устойчивости.

Compressibility of disturbed-structure strong rocks is determined for predicting land subsidence and stability during operation of transport machines. The plate-bearing tests are carried out on a large bench tester at different normal pressures and different densities of strong overburden rocks. The method to estimate deformability of strong overburden rocks using a plate and a station rod is described. The results were used to assess passability of transport machines during damming and for the damp stability calculation.
МАССОПЕРЕНОС ПРИ ФИЛЬТРАЦИОННОМ ВОСХОДЯЩЕМ ДВИЖЕНИИ ВОДНЫХ РАСТВОРОВ В ОТХОДАХ ОБОГАЩЕНИЯ
Authors: А.Г. МИХАЙЛОВ , И.И. ВАШЛАЕВ , Е.Н. МЕРКУЛОВА , Н.Ф. УСМАНОВА , А.Е. ЗУЕВ
Published: October 2024

Представлены результаты экспериментальных исследований по восходящему фильтрационному массопереносу водным раствором согласно природному механизму движения растворов к поверхности с испарением воды в атмосферу. Полезные компоненты, осаждаясь из растворов, формируют зоны концентрации на испарительном барьере. Эксперимент имитирует полный цикл процессов для материала хвостов флотационного обогащения полиметаллических руд: скважинная подача растворов с поверхности в донную часть техногенного массива; распределение растворов в массиве; капиллярный подъем на поверхность; осаждение и концентрация солей полезных компонентов на испарительном барьере. Исследования позволяют оценить технологическую применимость нового подхода и получить некоторые параметры массопереноса.

The article describes the experiment on the upward percolating mass transfer by water solution according to the natural mechanism of movement of solutions toward ground surface with water evaporation in atmosphere. Useful components settle out from the solutions and concentrate on the evaporation barrier. The experiment simulates a complete cycle of processes for flotation tailings of complex ore: feed of solutions in boreholes from surface to bottom of a tailings body; spreading of the solutions in the tailings body; capillary ascent to the surface; settling out and concentration of useful salts on the evaporation barrier. The usability of this approach and some parameters of the mass transfer process can be found from the relevant research.
Enhancing Supply Chain Synchronisation in the Fast Moving Consumer Goods Industry
Authors: Mzavanadze Neringa , Tolocka Eligijus
Published: October 2024

In 2021–2022, a decade’s worth of disruptions battered material supply chains, establishing them as a permanent factor. COVID-19 caused labour shortages, rising fertiliser costs altered farming, Europe faced energy crises, USA-China tensions grew, and the Ukraine-Russia war escalated. Extreme weather and policy shifts worsened global supply chains, leading to bare shelves and crippled businesses. Just-in-time delivery failed, and traditional supply chains no longer ensure business continuity. This article aims to prove the inefficiencies of traditional supply chains and offer an approach to creating an end-to-end model with better visibility, service, and cost control for Fast-Moving Consumer Goods (FMCG) manufacturing plants. During the research phase, 12 European Pet food production plants were visited, analysing their supply chains via People/Systems/Process lenses. Risks, synchronisation needs, system requirements and training gaps were identified. Preliminary research findings are presented in this article.
Are the criminal procedure constraints experienced by a person properly evaluated during the imposition of a penalty?
Authors: Krušinskas Vidas , Valickas Liutauras
Published: October 2024

The article examines the challenges of ensuring proper protection of human rights, that occur due to criminal procedure constraints, also their evaluation during the implementation of criminal liability (imposition of a penalty). The aim of the study is to thoroughly analyse the evaluation of challenges of ensuring the protection of human rights, caused by the criminal procedure constraints during the implementation of criminal liability. Consequently, various sources of information were examined, including the current legislation, case law, legal doctrine and statistical data. As a result, it was concluded that the realization of the right to criminal proceedings within a reasonable time and the imposition of coercive measures, particularly – of detention, are the most significant aspects of the subject matter. Therefore, person’s right to criminal proceedings within a reasonable time is the most important feature of criminal procedure that is evaluated by the court when implementing criminal liability, while considering not only the factual length of proceedings, but also various other circumstances, consequently, if this right has been violated, the imposed penalty should be reduced or suspended. Meanwhile, the coercive measures imposed during the criminal proceedings are not evaluated as much – detention is the only measure that is taken into account when imposing penalty. The analysis of statistical data has revealed positive trends towards rapid criminal proceedings and rarer detention of suspects. Finally, the conducted survey of law practitioners and theorists revealed that, according to their opinion, the importance of the subject matter is exceptionally significant and it is often desired to change or improve the existing legislation or case law in order to evaluate the constraints of human rights that are experienced by a person during the criminal proceedings more carefully.
A TRANSISTOR CONVERTER WITH LOAD IMPEDANCE MATCHING OF INDUCTION HEATING EQUIPMENT WITH TWO/THREE FREQUENCY OUTPUT CURRENT
Authors:   Institute of Electrodynamics National Academy of Sciences of Ukraine, Beresteiskyi Ave., 56, Kyiv, 03057, Ukraine, Yurchenko O.M. , Gurin V.K. ,   Institute of Electrodynamics National Academy of Sciences of Ukraine, Beresteiskyi Ave., 56, Kyiv, 03057, Ukraine, Tverdokhlib Yu.O. ,   Institute of Electrodynamics National Academy of Sciences of Ukraine, Beresteiskyi Ave., 56, Kyiv, 03057, Ukraine
Published: October 2024

This paper presents a schematic solution of a transistor converter for induction heating equipment featuring two/three-frequency output current. The proposed solution enables discrete adjustment of the input voltage of the inverter within the converter, facilitating alignment with the load impedance of the induction heating equipment through the sequential modulation of currents at different frequencies. Detailed descriptions of the operational modes of the DC/DC converter are provided, highlighting its unique characteristic of operating semiconductor elements in an almost static mode with minimal dynamic losses. This innovative approach not only enhances energy efficiency but also elevates electromagnetic compatibility in converters designed for induction heating equipment with two/three-frequency output currents. References 10, figures 4.
Czy z obozu da się wyjść? KZ-syndrom, trauma oraz problem postpamięci na przykładzie powojennych relacji KL Auschwitz
Authors: Gardias Magdalena
Published: October 2024

The article focuses on the problem of KZ-syndrome and the way it was formulated in the post-war texts of former prisoners of concentration camp Auschwitz, which were published or still not, from archives located, among others in Oświęcim, Terezin, Prague or Lublin. The article was concern only on Czech and Polish texts, which I currently deal with. The side aspect of the work is the problem of trauma and of post-memory, difficult past inherited from former prisoners of the KL Auschwitz by the second and next generations. This article is a review, and main purpose is to discover the value of these texts still enclosed in the archival space and also see for special status of authors of these texts.
Лексичні і лексико-стилістичні помилки польськомовних студентів в українській мові
Authors: Баранівська Оксана
Published: October 2024

The aim of the study is to analyse lexical and lexical-stylistic mistakes in Ukrainian among Polish-speaking students of the Jagiellonian University who are learning Ukrainian as a foreign language. The lexical mistakes observed in both spoken and written Ukrainian can be divided into the following groups: 1) mistakes occuring only in the speech of Polish-speaking students (interlingual homonyms and their incorrect (invented) equivalents due to the influence of the mother tongue); 2) mistakes that can be noticed not only in the speech of foreigners, but mainly in the speech of Ukrainian native speakers. These mistakes are most often caused by linguistic interference. This refers to the difficulty in choosing the right word from a number of synonyms. This group of mistakes can also include examples of pleonasms and paronyms, and, less frequently, tautologies
Dynamically adaptive materials
Authors: Kang Sung Hoon
Published: October 2024

Materials experience various environmental changes during use. However, materials used for engineering applications tend to have fixed properties. The lack of adaptability increases costs, weight, and environmental impacts for structural applications because of material selection for the worst-case scenario. Similarly, the lack of adaptability limits the performance of functional materials that are used, such as with camouflage, wetting ability, and adhesion properties, because as-synthesized materials are optimized for a specific operation environment. Biological organisms address this challenge by dynamically changing the characteristics of materials based on their environment. It will be desirable for next-generation synthetic materials to adopt the capability to adapt to dynamically changing operating environments. In this issue, recent efforts to develop dynamically adaptive materials for different environmental conditions and stimuli will be introduced for a broad materials community. Then, the current challenges and future research opportunities will be discussed, followed by potential scientific and societal impacts of dynamically adaptive materials.

Graphical abstract
Women of reproductive age endogenous intoxication level assessment after surgical treatment of endometriosis
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Dyndar O.A. , Dymarska O.Z. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: October 2024

Endometriosis develops and progresses under conditions of initial endogenous intoxication (EI) and negative changes in the body's reactivity. Surgical treatment is accompanied by tissue destruction at the site of trauma, aseptic inflammation, pathological protein catabolism, and massive cell death, which may lead to the development of a syndrome of mutual aggravation. Aim - to determine the level of EI in women of reproductive age with endometriomas, depending on the surgical treatment method. Materials and methods. A laparoscopic surgical treatment was performed on 120 reproductive-aged patients with ovarian endometriomas. The Group I consisted of 60 women who underwent bipolar coagulation (BPC) of the ovarian medullary layer, while the Group II included 60 women who received BPC of both the medullary and cortical layers. The EI level was assessed postoperatively based on the clinical course during the postoperative period, general blood test indicators, and biochemical markers of tissue destruction products (TDP). Results. In the postoperative period, patients in the Group I showed lower levels of TDP such as medium-mass molecules (MMM280, MMM254), acid-soluble fractions of nucleic acids (ASFNA), malondialdehydes of thiobarbituric acid (TBA), and a 2.2 times higher endotoxic index (ETI) than women in the Group II. Conclusions. After laparoscopic surgery with BPC of the ovarian medullary layer, the EI level showed less significant manifestations, as confirmed by a 1.3-fold decrease in MMM280, MMM254, and ASFNA levels, a 1.2-fold decrease in TBA levels, and a 2.2-fold increase in ETI levels. The most sensitive and early markers of tissue destruction in reproductive-aged women with endometriomas after laparoscopic surgery with BPC are ASFNA and TBA. Among patients who underwent laparoscopic surgery with BPC of the medullary layer, leukocytosis was 1.3 times less common, the number of patients with elevated C-reactive protein levels was 1.2 times lower, and the rehabilitation period was reduced by 1.2 times compared to patients who received BPC of both the medullary and cortical layers of the ovary. The study was conducted in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the local ethics committee of the participating institution. Informed consent was obtained from all patients. The authors declare no conflict of interest.