THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors
Authors: Alexander Stephen P H , Christopoulos Arthur , Davenport Anthony P , Kelly Eamonn , Mathie Alistair , Peters John A , Veale Emma L , Armstrong Jane F , Faccenda Elena , Harding Simon D , Pawson Adam J , Southan Christopher , Davies Jamie A , Abbracchio Maria Pia , Alexander Wayne , Al‐hosaini Khaled , Bäck Magnus , Barnes Nicholas M. , Bathgate Ross , Beaulieu Jean‐Martin , Bernstein Kenneth E. , Bettler Bernhard , Birdsall Nigel J.M. , Blaho Victoria , Boulay Francois , Bousquet Corinne , Bräuner‐Osborne Hans , Burnstock Geoffrey , Caló Girolamo , Castaño Justo P. , Catt Kevin J. , Ceruti Stefania , Chazot Paul , Chiang Nan , Chini Bice , Chun Jerold , Cianciulli Antonia , Civelli Olivier , Clapp Lucie H. , Couture Réjean , Csaba Zsolt , Dahlgren Claes , Dent Gordon , Singh Khuraijam Dhanachandra , Douglas Steven D. , Dournaud Pascal , Eguchi Satoru , Escher Emanuel , Filardo Edward J. , Fong Tung , Fumagalli Marta , Gainetdinov Raul R , Gasparo Marc de , Gerard Craig , Gershengorn Marvin , Gobeil Fernand , Goodfriend Theodore L. , Goudet Cyril , Gregory Karen J. , Gundlach Andrew L. , Hamann Jörg , Hanson Julien , Hauger Richard L. , Hay Debbie L. , Heinemann Akos , Hollenberg Morley D. , Holliday Nicholas D. , Horiuchi Mastgugu , Hoyer Daniel , Hunyady László , Husain Ahsan , IJzerman Adriaan P. , Inagami Tadashi , Jacobson Kenneth A. , Jensen Robert T. , Jockers Ralf , Jonnalagadda Deepa , Karnik Sadashiva , Kaupmann Klemens , Kemp Jacqueline , Kennedy Charles , Kihara Yasuyuki , Kitazawa Takio , Kozielewicz Pawel , Kreienkamp Hans‐Jürgen , Kukkonen Jyrki P. , Langenhan Tobias , Leach Katie , Lecca Davide , Lee John D. , Leeman Susan E. , Leprince Jérôme , Li Xaria X. , Williams Tom Lloyd , Lolait Stephen J. , Lupp Amelie , Macrae Robyn , Maguire Janet , Mazella Jean , McArdle Craig A. , Melmed Shlomo , Michel Martin C. , Miller Laurence J. , Mitolo Vincenzo , Mouillac Bernard , Müller Christa E. , Murphy Philip , Nahon Jean‐Louis , Ngo Tony , Norel Xavier , Nyimanu Duuamene , O’Carroll Anne‐Marie , Offermanns Stefan , Panaro Maria Antonietta , Parmentier Marc , Pertwee Roger G. , Pin Jean‐Philippe , Prossnitz Eric R. , Quinn Mark , Ramachandran Rithwik , Ray Manisha , Reinscheid Rainer K. , Rondard Philippe , Rovati G. Enrico , Ruzza Chiara , Sanger Gareth J. , Schöneberg Torsten , Schulte Gunnar , Schulz Stefan , Segaloff Deborah L. , Serhan Charles N. , Stoddart Leigh A. , Sugimoto Yukihiko , Summers Roger , Tan Valerie P. , Thal David , Thomas Walter (Wally) , Timmermans Pieter B. M. W. M. , Tirupula Kalyan , Tulipano Giovanni , Unal Hamiyet , Unger Thomas , Valant Celine , Vanderheyden Patrick , Vaudry David , Vaudry Hubert , Vilardaga Jean‐Pierre , Walker Christopher S. , Wang Ji Ming , Ward Donald T. , Wester Hans‐Jürgen , Willars Gary B , Woodruff Trent M. , Yao Chengcan , Ye Richard D. 
Published: September 2021

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found athttp://onlinelibrary.wiley.com/doi/bph.15538. G protein‐coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.