ІНФОРМАЦІЙНО-ОРГАНІЗАЦІЙНЕ ЗАБЕЗПЕЧЕННЯ ФАРМАЦЕВТИЧНОЇ ДОПОМОГИ ХВОРИХ НА ЕПІЛЕПСІЮ
Authors: Гриньків Я. О. , Блавацька О. Б. , Лозинська М. О. 
Published: September 2015

<p><strong>INFORMATIONAL-ORGANIZATIONAL PROVIDING OF PHARMACEUTICAL CARE FOR PATIENTS WITH EPILEPSY</strong></p><p><strong>Y.O.Hrynkiv, O.B.Blavatska, M.O. Lozynska</strong></p><p>Danylo Galytskyj Lviv National Medical University, Lviv</p><p><strong>Summary:</strong> The analysis of information on antiepileptic medicines (AEM) in standardized clinical protocols of medical care for patients with epilepsy, State Medicinal Formulary (SMF) of Ukraine 6th and draft 7th editions and comparison of information about AEM in these sources with the State Register of Medicines. It was found that currently registered AEM arsenal (14 INN) is mentioned in the main text of these sources of information and standardized clinical protocols of primary, emergency, secondary and tertiary medical care for patients with epilepsy.</p><p><strong>Keywords:</strong> Antiepileptic Medicines (AEM), State Medicinal Formulary (SMF), State Register of Medicines (SRM).</p><p><strong>Introduction.</strong> About 50 million people worldwide have epilepsy, nearly 80% of them live in developing countries. Epilepsy responds the treatment about 70% of cases, yet about three fourths of affected people in developing countries do not get the treatment they need. Epilepsy and epileptic syndromes is one of the most widespread and socially significant diseases of the nervous system. The prevalence of epilepsy in the general population in most European countries is 80-230 cases per 100 thousand people. In Ukraine in average of 50-73 persons per 100 thousand suffer from it. According to majority epidemiological studies conducted in our country and abroad, today an increase of the part of epilepsy in the general structure of nervous system diseases from 0.5 to 0.8-1.2%.</p><p>The purpose of this study is to analyze standardized clinical protocols of medical care for patients with epilepsy (Ministry of Health of Ukraine order № 276 from 17.04.2014), State Formulary of Ukraine 6th edition (approved by the Ministry of Health of Ukraine order № 252 from 08.04.2014), draft of 7th edition of the State Formulary, and compare information about AEM in these sources with the State Register of medicines of Ukraine.</p><p><strong>Methods.</strong> To achieve the goals and objectives methods of information retrieval, comparative analysis, synthesis, system, target-oriented were used.</p><p><strong>Results and discussion</strong>. By the latest official data of Ministry of Health (2012) there are about 100,000 patients with epilepsy in Ukraine, but this figure taking into account the statistical average of global prevalence of the disease, most likely is understated. In connection with the providing of medical care for patients with epilepsy by neurologists and psychiatrists, respectively, due to the double coding and registration of clinical expertise and epidemiology, statistics data are fundamentally incorrect and need a new regulation.</p><p>According to the analyzed sources one can say that standardized clinical protocol of primary, emergency, secondary (specialized) and tertiary (highpecialized) medical care "Epilepsy in Adults" contains the largest number of AEM, which can be used, but not all of them are registered in Ukraine and exist in State Formulary. Eslikarbazepin (registered in Ukraine under the brand name "Eksaliyef" from July 2012.) is the only currently registered in Ukraine AEM not included in the list of medicines that can be purchased with state funds.</p><p>Almost all of these medicines are prescribed on the ordinary prescription forms F-1 and do not stand in the subject-quantifiable accounting (except phenobarbital: the F-3 form, SQA), which increases the physical availability of antiepileptic drugs.</p><p><strong>Conclusions.</strong> Arsenal of AEM currently registered in Ukraine generally corresponds with the standardized clinical protocol of primary, emergency, secondary (specialized) and tertiary (highspecialized) medical care for patients with epilepsy; adopted Clinical guideline on epilepsy and State Formulary 6th edition. 93% AEM, which are currently registered in Ukraine can be purchased by public funds, which gives patients the opportunity to receive adequate and appropriate treatment.</p>