bluuebunny/crossref_metadata_2025 huggingface dataset:
Simulator Design Based on Production Automation Equipment Model
Authors:   Korean Industrial Technology Convergence Society, Lee Go-Eun
Published: July 2022

The recent development of ICT technology arising from the Fourth Industrial Revolution has resulted in the digitization of the production system, which is changing the paradigm of the manufacturing site and is being presented as a new concept of the digital twin. Manufacturing and production systems can be categorized into information technology and operation technology systems. Owing to the advent of digital twins, sophisticated and accurate models for the manufacturing lifecycle are necessitated. To evaluate a digital twin-based simulation model, we propose a design technology that can pre-examine the feasibility of the work procedure by applying a production automation equipment control simulator at the engineering stage.
High-Performance Liquid Chromatography (HPLC): A review
Authors: Abdu Hussen Ali
Published: July 2022

Today HPLC is widely applied for separations and purifications in a variety of areas including pharmaceuticals, biotechnology, environmental, polymer and food industries. It is accomplished by injection of a small amount of liquid sample into a moving stream of liquid (called the mobile phase) that passes through a column packed with particles of the stationary phase. The separation of a mixture into its components depends on different degrees of retention of each component in the column. HPLC is just one type of liquid chromatography, meaning the mobile phase is a liquid. Reversed-phase HPLC is the most common type of HPLC. The reversed-phase means the mobile phase is relatively polar, and the stationary phase is relatively non-polar. HPLC instrumentation includes a Solvent reservoir, pump, injector, column, detector, and integrator or acquisition and display system. The heart of the system is the column where separation occurs. The information that can be obtained using HPLC includes identification, quantification, and resolution of a compound. The major applications are in the area of Pharmaceuticals, food, research, manufacturing, forensics, and bio-monitoring of pollutants.
Synthesis and characterization of CdS/CeO2 Nanocomposite with improved visible-light photocatalytic degradation of methyl orange dye
Authors: Tigabu Bekele Mekonnen
Published: July 2022

Different types of photocatalysts in single and binary systems in different molar ratios were synthesized by the co-precipitation method. Crystal structure, surface area, morphology, bandgap energy, functional groups, and optical properties of the as-synthesized photocatalysts were characterized by using XRD, BET, SEM-EDX, UV/Vis, FTIR, and PL instruments, respectively. Photocatalytic activities of the single and binary composite were evaluated by using an aqueous solution of model pollutant MeO. Photocatalytic activities of binary CdS/CeO2 (1:1) nanocomposite were found to be higher than those of single counterparts. The degradation efficiencies of the binary system were found to be 53.73%. The reusability of the binary photocatalyst was tested and only about 33% decrement was observed after four successive runs. The degradation of MeO dye follows the pseudo-first-order kinetics for the entire as-synthesized nanocomposite. The results also suggest that in the CdS/CeO2 (1:1) composite the photoinduced electrons and holes can be effectively separated.
Descripción de rasgos léxicos de textos profesionales producidos por estudiantes de derecho y medicina
Authors: Meza Paulina , Lillo-Fuentes Fernando , González-Catalán Felipe
Published: July 2022

En el marco de una investigación exploratorio-descriptiva, nuestro objetivo es describir los rasgos léxicos de textos profesionales con fines académicos producidos por estudiantes de Derecho y Medicina. Para ello, analizamos el corpus TeProFAc, constituido por 123 textos de Derecho y Medicina. Los rasgos explorados fueron: terminologí­a, colocaciones, tiempos verbales, marcadores de subjetividad, siglas y abreviaturas. Entre los principales resultados, destacamos que algunas categorí­as permitieron establecer distinciones entre disciplinas, a saber, terminologí­a, siglas, abreviaturas y marcadores de subjetividad; mientras que las colocaciones ni el uso de tiempos verbales evidenciaron diferencias disciplinares. En conclusión, la naturaleza de cada disciplina se ve reflejada en los rasgos léxicos de los textos producidos por los estudiantes de Derecho y Medicina.
The incorporation of indigenous loanwords into spanish and english translations of a text by a 16th-century german traveller
Authors: Santana-Quintana M. Cristina
Published: July 2022

This essay is based on a description of indigenous words in the work of the German chronicler Ulrich Schmidel (1510-1579), one of the few German-language accounts of the conquest that refers to an early period of colonialism. First, we will compile an inventory of the indigenous words found in the selected text and investigate what kind of strategies and procedures are used, in order to then carry out a comparative case study on how these lexical indigenisms are introduced into the English and Spanish translations of the original German text. We will present the similarities or differences that can be found in the texts researched, and if possible we will make a case for the criteria used for the chosen terms, in other words, whether there is any notable trend when incorporating the loanwords into the chronicles, and whether they aid a better understanding of the process of contact between languages and cultures.
Más allá del naturalismo y las bellas enfermas. "El velo de la Purí­sima", de Adela Zamudio y "A caolha", de Júlia Lopes de Almeida y la representación de la enfermedad como metáfora crí­tica de la modernidad industrial en el entre siglos latinoamericano
Authors: Morales Pino Luz Ainaí­
Published: July 2022

Este trabajo analiza las representaciones de la enfermedad y la deformidad femenina en las obras de dos escritoras del entre siglos, la boliviana Adela Zamudio y la brasileña Júlia Lopes de Almeida. El objetivo es ahondar en los usos distintivos de la metáfora patológica con relación al tratamiento de la enfermedad y, sobre todo, la enfermedad femenina, desde las matrices ideológicas y estéticas modernistas-decadentistas y naturalistas. Mientras el modernismo-decadentismo patriarcal se caracterizó por ensalzar y estetizar la enfermedad femenina hasta convertirla en un ideal estético; y mientras el naturalismo usó la enfermedad femenina para explicar las causas de la degeneración socio-nacional, Zamudio y Lopes de Almeida presentan en sus textos un tratamiento distinto de la enfermedad donde lo patológico y la deformidad no son ni marcas deterministas ni ideales estéticos o de singularidad, sino metáforas crí­ticas de una modernidad industrial que relega a la mujer a la marginalidad. Así­, reclaman el reconocimiento del trabajo femenino y el acceso de las mujeres a los medios de producción; al tiempo que crean las condiciones de posibilidad para una lectura interseccional y crí­tica de los arquetipos hegemónicos de lo femenino (el ideal de la mujer-madre-ángel del hogar), al mostrar que estos imperativos conductuales son privilegios de clase exclusivos a las mujeres de cierto grupo socio-racial.
EEG neurofeedback and isolation stressor. A systematic review
Authors: Gotner Kacper , Dornowski Marcin
Published: July 2022

Introduction. One of the factors increasing the body's response to a stressful situation is isolation. The feeling of loneliness in isolation can be caused by biological, psychological or medical factors. Material and methods: This paper is a review of publications issued in 2009–2021, the most up-to-date in terms of information on the topic of stress and its links with EEG neurofeedback. Results: 5 publications on stress caused by isolation and the reaction of the human body in a stressful situation were selected. The papers were selected based on the use of EEG neurofeedback in reducing the body's stress reactions to isolation. Conclusions: There is a lack of studies in the available literature describing the direct application of EEG neurofeedback in the reduction of stress caused by isolation despite demonstrating its potential in individual studies.
“Many women use contraceptives in secret”: a qualitative study of health provider perspectives regarding barriers and enablers to reproductive health and antenatal care services in rural Tanzania
Authors: Chelva Melinda , Chard Sidonie , Eberle Alexa , Lucchese Alexandra , Kaushal Sanchit , West Nicola , Marandu Prisca Dominic , Smith Graeme , Erwin Erica , Tillya Robert Philemon , Nswilla Anna , Yeates Karen
Published: July 2022

Background

Women in sub-Saharan Africa face numerous barriers to reproductive health and antenatal care (ANC) services. The objective of this study was to identify health provider perspectives regarding the barriers and enablers to reproductive health, ANC, and postnatal care (PNC) services in rural Tanzania.

Methods

A qualitative study was conducted in four districts of Tanzania and utilized key informant interviews (KIIs) and focus group discussions (FGDs). An interview guide was developed, focusing on individual and community-based factors (barriers and enablers) to accessing ANC and PNC services. Data were collected during December 2017 and May 2018 and analyzed using a thematic approach.

Results

Two major themes were identified as barriers to women accessing ANC and PNC services. First, factors related to women in the context of their family and community, for example (i) lack of autonomy in a patriarchal society, (ii) lack of knowledge and education regarding healthy pregnancy and pregnancy complications, (iii) lack of financial resources or control over financial resources, (iv) use of traditional birth attendants, (v) lack of male involvement, (vi) cultural beliefs as barriers to accessing family planning and ANC and PNC services. Second, factors present in the health system, for example (i) lack of infrastructure, equipment and health provider resources at health facilities, and (ii) lack of confidentiality and feelings of stigmatization when receiving health services. Reduced stigmatization against women with Human Immunodeficiency Virus (HIV) served as an enabler.

Conclusions

Overall, this study highlights the need to implement more initiatives in these rural districts to improve ANC and PNC services uptake. It also indicates the need to find strategies to improve male involvement and family support in the local context.
Upaya Mengembangkan Asesmen Keterampilan Pemecahan Masalah Pada Materi Ekosistem Berdasarkan Greenstein
Authors: Modok Sonya Getrida , Dwi Ari Budiretnani  , Mumun Nurmilawati  , Sulistiono
Published: July 2022

Kemampuan pemecahan masalah sangat diperlukan karena peserta didik dapat belajar memahami konsep-konsep dengan menggunakan masalah nyata pada konteks kehidupan sehari-hari. Tujuan penelitian adalah mengembangkan instrumen asesmen keterampilan pemecahan masalah berdasarkan Greenstein. Penelitian ini dengan metode pengembangan R&D (Researt and Development)  model Plomp. Instrumen menggunakan lembar validasi ahli. Penelitian dibatasi pada pengujian kelayakan instrumen. Analisis data dengan teknik persentase. Hasil penelitian menunjukkan instrumen asesmen keterampilan pemecahan masalah layak dengan hasil validasi ahli praktisi 86,2% “Sangat Valid”, ahli asesmen 93% “Sangat Valid” , ahli materi 85,8% “Sangat Valid”, dan ahli bahasa 83,2% “Cukup Valid”. Hasil uji validitas pada butir soal dengan kategori layak diperoleh 17 soal ‘‘Valid”. Hasil uji reliabilitas diperoleh hasil sebesar 0,752  “reliabilitas tinggi”.
Peran Iklim Organisasi Terhadap Perilaku Kerja Inovatif Dengan Perilaku Berbagi Pengetahuan Sebagai Mediasi (Studi Kasus Pada Industry Pariwisata)
Authors: Metha Aurum Zukhrufani Ainulisany  , Tulus Budi Sulistyo Radikun
Published: July 2022

Penelitian ini bertujuan untuk menguji peran prediksi iklim organisasi dalam innovative work behavior (IWB) atau perilaku kerja inovatif selama masa pandemi COVID-19 dengan knowledge sharing behavior atau perilaku berbagi pengetahuan sebagai mediator antara keduanya. Variabel-variabel tersebut dipilih karena diasumsikan berpengaruh terhadap kelangsungan usaha di industri pariwisata selama masa pandemi. Metode penelitian ini yaitu berupa penelitian kuantitatif cross-sectional pada individu yang bekerja di industri pariwisata baik lembaga pemerintah maupun non pemerintah. Studi ini dilakukan pada sampel yang dipilih sebanyak 84 karyawan yang pekerjaannya berkaitan dengan pariwisata di seluruh negeri. Uji mediasi Macro Process Hayes dilakukan untuk menguji hipotesis. Hasil penelitian menunjukkan bahwa perilaku berbagi pengetahuan berperan signifikan sebagai mediator pada hubungan antara iklim organisasi dan perilaku kerja inovatif. Disarankan bahwa PBP diteliti tidak menjadi mediator antara iklim organisasi dan IWB karena kemungkinan ia dapat berdiri sendiri sebagai variabel prediktor. Pemeriksaan proses persepsi karyawan tentang iklim mereka dan dampaknya terhadap perilaku inovatif membutuhkan waktu yang relatif lebih lama
Peran Mediasi Recovery Experience dalam Hubungan antara Workplace Telepressure dan Work-Life Balance Pada Karyawan yang Tidak Memiliki Pasangan
Authors: Putri Komang Meydiana Hutama , Endang Parahyanti
Published: July 2022

Teknologi komunikasi saat ini menciptakan fenomena paradoks dimana angkatan kerja mengalami workplace telepressure. Angkatan kerja senantiasa merasakan tekanan dari ekspektasi untuk selalu terhubung dengan pekerjaan sehingga, ia tidak dapat mencapai pemulihan (recovery experience) yang dapat membantu untuk menghadapi tugas serta peran dalam bekerja dan kehidupan pribadi. Penelitian ini bertujuan untuk menguji peran mediasi dari dimensi-dimensi pemulihan dalam hubungan antara workplace telepressure dan work-life balance melalui metode regresi Hayes. Hasil menunjukkan tidak ditemukan peran mediasi yang signifikan dari dimensi-dimensi pemulihan dalam hubungan antara workplace telepressure dan work-life balance. Implikasi teoritis dari penelitian ini adalah terdapat faktor lain seperti power distance dan tipe aktivitas yang dapat mempengaruhi hubungan antar variabel dalam peneilitian. Implikasi praktis dari peneltiian ini adalah penting bagi pihak organisasi untuk menentukan batasan kapan pegawai diekspentasikan untuk bekerja dan beristirahat.
Peran Grit sebagai Moderator Hubungan Antara Ketidakamanan Kerja Dan Kepuasan Kerja Pada Karyawan Terdampak Kebijakan Covid-19
Authors: Auliya Andina Ramadhiyanti  , Alice Salendu
Published: July 2022

Pandemi Covid-19 menimbulkan perubahan dalam berbagai aspek kehidupan, termasuk juga berdampak pada perusahaan dan karyawan. Perusahaan menerapkan beberapa kebijakan sebagai upaya adaptasi terhadap perubahan yang dihadapi. Penelitian ini bertujuan untuk melihat peran grit sebagai moderator pada hubungan antara ketidakamanan kerja dan kepuasan kerja pada karyawan. Pendekatan penelitian ini adalah kuantitatif dengan desain cross sectional study, dilaksanakan dengan menyebarkan kuesioner secara daring menggunakan teknik non-probability sampling. Alat ukur yang digunakan telah melalui uji coba terlebih dahulu yaitu The Minessota Satisfaction Questionnaire (MSQ) short-form, Multidimensional Qualitative Job Insecurity Scale (MQJIS), dan short grit scale (Grit-S). Populasi penelitian ini adalah karyawan yang perusahaannya melakukan perubahan kebijakan akibat pandemi Covid-19. Analisis data yang dilakukan yakni uji korelasi dan uji moderasi menggunakan PROCESS Hayes Model 1. Data yang dalam analisis sebanyak 748 partisipan. Hasil analisis statistik menunjukkan efek interaksi antara ketidakamanan kerja dan grit terhadap kepuasan kerja signifikan (b = -0,02, 95% CI [-0,04, -0,01],   t=-3,09, p<0,05). Dengan demikian dapat disimpulkan bahwa grit berperan sebagai moderator dalam hubungan antara ketidakamanan kerja dan kepuasan kerja. Analisis lanjutan yang dilakukan mendapatkan bahwa grit dapat melemahkan pengaruh negatif dari ketidakamanan kerja terhadap kepuasan kerja ketika grit pada tingkat kategori sedang dan tinggi.
Effects of the tempering temperature on microstructure and mechanical properties of X70 dual phase steel
Authors: SAMI ZIDELMEL , Omar Allaoui
Published: July 2022

This study uses direct quenching (DQ) heat treatment at an intercritical annealing temperature (IAT) of 800 °C to form a martensite-ferrite dual phase microstructure of X70 steel. The effects of tempering temperatures ranging from 200 to 500 °C on tensile properties in a dual-phase X70 steel are investigated. Carbon diffusion and redistribution in the microstructure are influenced by tempering. It was discovered that the amount of carbides increases with the tempered temperature, resulting in depleted carbon in martensite. Conversely, increasing the tempered temperature causes a decrease in ultimate tensile strength and yield strength while increasing elongation.
Simultaneous improvement of corrosion and mechanical properties of AA 5083 aluminum alloy
Authors: Tayyaba Qanita , Butt Adnan Qayyum , Shahzad Muhammad , Ali Tahir
Published: July 2022

In this study, the effects of cold-rolling and annealing on the structural, electrochemical, and mechanical properties of AA5083 in a simulated seawater environment are investigated. The results demonstrated that annealing temperature significantly affects the alloy's mechanical and corrosion properties. According to potentiodynamic results, the rate of corrosion decreased after annealing. Compared to the cold-rolled sample, the heat treatment doubles the electrochemical impedance, indicating that the corrosion resistance of AA5083 alloy is suitable at 50°C annealing. Approximately twice as much ductility was added to the materials as compared to the as-received materials. Additionally, the mechanical testing revealed the Portevin-Le Chatelier (PLC) Effect Type B band, which reflected the smaller grain size.
Effect of copper-graphite composite electrode on material removal rate and surface roughness in MONEL 400 during electrical discharge machining
Authors: Hadi Mustafa , Ibrahim Abbas
Published: July 2022

Electrical Discharge Machining (EDM) is one of the non-traditional machining processes commonly used for machining of hard to cut metals. Monel 400 is a nickel based superalloy used in various applications. The composite electrode is developed and applied to enhance the machining process by reducing the time of the process and the cost of the electrode manufacturing. The presented work is aimed to study the effect of copper, graphite, and copper-graphite composite electrodes with different parameters on the Material Removal Rate and Surface Roughness of Monel 400. Influences of discharge current (Ip), pulse on time (Ton), and pulse off time (Toff) have been investigated. Based on the Taguchi method, experiments were analyzed using ANOVA through Minitab 20. The results have manifested that compared to copper and graphite electrodes, the copper-graphite electrode achieved better values of material removal rate and surface roughness. The lowest value of surface roughness is 3.1413 μm as a result of the added graphite reinforcement particles.
The application of failure method probability for analyzing in pit dump stability at West Block ‘X’ pit PT Berau Coal - East Kalimantan
Authors:   Politeknik Sinarmas Berau Coal, Adriansyah Yan , Saprana Rifqi Dwi ,   Faculty of Geological Engineering, Universitas Padjadjaran, Sophian Irvan ,   Faculty of Geological Engineering, Universitas Padjadjaran, Khoirullah Nur ,   Faculty of Geological Engineering, Universitas Padjadjaran
Published: July 2022

West Block 'X' pit is one of the coal mining locations operated by the Lati Mine Operation – PT Berau Coal. Administratively, the Lati Mine is located as part of Berau Regency – East Kalimantan. The study area is located at the north side of the concession, in a syncline fold structure zone. The disposal design in this area needs to special attention from slope stability aspect due it is located on the wing of a mega syncline with a certain slope and constituent of unconsolidated materials. The pit design needs to be stable. The purpose of this study is to determine the level of stability of the in-pit dump by analyzing the current in-pit dump stability based on the value of the safety factor (FS) and the probability of failure (PoF). The method used in this study is a probabilistic analysis of slope stability based on the Morgenstern-Price method to obtain the value of the safety factor and the probability of failure. The study results show that the slope is in the safe category (stable slope) in the range of PoF values 0 – 1%, marginal slope 1 – 12%, and unstable slope above 12%. Based on such as results, it is necessary to modify the slope geometry categorized as unstable to carry out mine operation safely underneath the toe of slope.
Growth and production of tea plant (Camellia sinensis (L.) O Kuntze) after pruning with bio-organomineral ameliorant
Authors:   Research Institute for Tea and Chincona, Gambung, Wulansari Restu , Athallah Faris Nur Fauzi ,   Research Institute for Tea and Chincona, Gambung, Pranoto Eko ,   Research Institute for Tea and Chincona, Gambung, Maryono Maryono ,   Research and Development Centre for Mineral and Coal Technology, Darmawan Didit Adi ,   Research and Development Centre for Mineral and Coal Technology, Supriyanto Budhy Agung ,   Research and Development Centre for Mineral and Coal Technology
Published: July 2022

Tea plant (Camellia sinensis (L.) O Kuntze) is one of the important plantation commodities that has long been cultivated in Indonesia. Mineral based ameliorant fertilization is one of the important factors to produce high productivity and maintenance of healthy plants. Ameliorant bio-organomineral (BIOM) is a fertilizer that utilizes mineral resources, potential microbes, and organic matter. This study aimed to determine the effect of BIOM's ameliorant on plant health and tea productivity after pruning. The Randomized Block Design (RBD) was accomplished by 8 treatments and three replications (100% conventional fertilizer, 100% BIOM, 80% single fertilizer + 100% BIOM, 80% conventional fertilizer + 80% BIOM, 80% conventional fertilizer + 60% BIOM, 60% conventional fertilizer + 100% BIOM, 60% conventional fertilizer + 80% BIOM, and 60% conventional fertilizer + 60% BIOM). The results showed that there was a significant effect of the combination of conventional fertilizer and BIOM ameliorant on shoot production and pekoe percentage, but not significantly different in tipping production, pekoe shoot ratio and banji shoots. The combination of 60% conventional fertilizer and 60% BIOM showed the highest total production of 31.81 kg/plot. Shoot production in the BIOM treatment was 17.36% higher than that of the conventional fertilizer application. The application of BIOM ameliorant was able to improve the plant health after pruning on the GMB 7 clone.
DFT computational study of pyridazine derivatives as corrosion inhibitors for mild steel in acidic media
Authors: Robert Oluwaseyi Ogede  , Nurudeen Abdulafeez Abdulrahman  , Dasola Airat Apata
Published: July 2022

The molecular structures of two Pyridazine derivative;5-phenyl-6-ethyl-pyridazine-3-thione (PEPT) and 5-phenyl-6-ethylpridazine-3-one (PEPO) were simulated for corrosion inhibition efficiency using quantum chemical calculations based on density functional theory (DFT) at the B3LYP/6-31G* basis set level in order to compare the relationship between their molecular structure,electronic structure and inhibition potential.The quantum chemical properties for inhibition efficiency such as EHOMO (energy of the highest occupied molecular orbital), ELUMO (energy of the lowest unoccupied molecular orbital), energy gap (ΔE), dipole moment (μ), global hardness (η), global softness (S), electronegativity (χ), electrophilicity (ω), nucleophilicity (ɛ), electrons transferred from inhibitors to metal surface (ΔN), and the energy change during electronic back-donation process (ΔE*) were calculated. The results show that 5-phenyl-6-ethyl-pyridazine-3-thione (PEPT) would have higher inhibition efficiency than 5-phenyl-6-ethylpridazine-3-one (PEPO) due to its relative EHOMO, ELUMO, ΔE, μ, η, S , ꭓ, ω, ΔN, and ∆E*.
Impact of Ethanolic Extract of Dissotis rotundifolia Leaves on Wistar Rat Erythrocyte Membrane
Authors: Ebizimor Wodu  , Abraham Sisien Eboh
Published: July 2022

Medicinal plants have been shown to affect the stability of the erythrocyte membrane. Dissotis rotundifolia leaves have been used in Nigeria to treat certain diseased conditions not minding the effect on the erythrocyte membrane. The aimed of this work is to investigate the impact ethanolic extract of Dissotis rotundifolia leaves have on wistar rat erythrocyte membrane. Twenty-five adult wistar albino rats were randomly distributed into five groups administered 0 (control), 50, 100, 150 and 200 mg/100 g body weight. Erythrocytes osmotic fragility was determined by measuring the release of haemoglobin from blood added to tubes containing serially diluted phosphate buffered saline (PBS, pH 7.4). The results of mean corpuscular fragility (MCF) showed non-significant (p > 0.05) decrease for 50 and 100 mg/100 g body weight doses, while 150 and 200 mg/100 g body weight doses showed non-significant (p > 0.05) increase. The erythrocytes were stabilized by 50, 100 and 150 mg/100 g body weight, while 200 mg/100 g body weight destabilized the erythrocyte membrane. Also, 200 mg/100 g body weight dose showed significant (p ≤ 0.05) increase in malondialdehyde (MDA) levels. At relatively high doses, Dissotis rotundifolia may induce oxidative stress causing significant levels of MDA production resulting in alteration of the chemical and structural composition of the membrane. In conclusion Dissotis rotundifolia at low doses may be useful in maintaining the erythrocyte by stabilizing the membrane, whereas high doses destabilize the membrane and compromise membrane integrity.
Assessment of co-infection of typhoid and malaria in patients attending F.M.C Umuahia Abia state
Authors: Joy Nkeiruka Dike-Ndudim  , Francisca Ibe Cajethan  , Chizaram Winners Ndubueze
Published: July 2022

Malaria and typhoid fever are major public health problems in tropical and subtropical countries. People in endemic areas are at risk of contracting both infections concurrently. This study was aimed at assessing malaria and co-infection of typhoid fever among patients. A cross-sectional study was conducted on 256 patients suspected for malaria and typhoid fever from March to August 2017 at Federal Medical Centre Umuahia Abia State. Blood samples were collected for blood film preparation and widal test. The prevalence of malaria was 78.90% (n = 202). Among these age groups, (11 – 15), (16 – 20), (21 – 25) and (26 – 30) years were mostly infected. The seroprevalence of typhoid fever was found high and poor hand washing habit were associated with typhoid fever infection. Further studies should be done on malaria and typhoid fever co-infection in different seasons and different study areas.
Opening and closing in morphological image processing
Authors: Sunil Bhutada  , Nakerakanti Yashwanth  , Puppala Dheeraj  , Kethavath Shekar
Published: July 2022

Morphological Image Processing is a useful tool in digital image processing because it can rigorously quantify many features of the geometrical structure of a way that is consistent with human intuition and perception. Morphological processing may remove noise and clutter from images, as well as alter them according to the size and shape of the items of interest. Linear Image Processing is sometimes used instead of Morphological Image Processing since it changes the underlying geometric form of an image, although Morphological Image Processing does not lose the image's information.
Implementasi Metode Double Exponential Smoothing pada Prediksi Jumlah Penjualan Kain Pantai
Authors: Dorestin Nacita Agnes , YS Wawan Laksito , Vulandari Retno Tri
Published: July 2022

Y2K Batik is an SME (Small and Medium Enterprise) engaged in batik. Y2K Batik produces and sells beach wear with various motifs. One of the important things in business is inventory of merchandise, inventory of merchandise is a factor in determining the success of a trading company to achieve its goals, because the goods sold affect the level of income to increase company profits. With these considerations, it is necessary to analyze the production of beach wear for the availability of merchandise in fulfilling customer orders. Based on the above background, the scope of the problem in this study is master data collection obtained from records of selling beach batik cloth periodically from time to time. By utilizing the existing data and applying certain methods, a sales forecasting prediction can be made using the Double exponential Smoothing method. From the results of calculations and testing of forecasting data on the Mandala Motif Beach Fabric variable with the most optimal value using = 0.9 of 2127 with an error value of 19.46% and an accuracy rate of 80.54% (Good). The Canting Motif Beach Wear variable with the most optimal value using = 0.9 of 3174 with an error value of 3.61% and an accuracy rate of 96.39% (Very Good). Double Exponential Smoothing is the most widely used method to determine the trend equation of the second smoothing data through a smoothing process. The programming language uses Microsoft Visual Studio 2013 and the DBMS uses Microsoft SQL Server 2012. The purpose of this research is to create a system that can simplify the process of analyzing the production of beach wear in order to meet the availability of goods ordered by customers.
Investigation of Shared Leadership Behaviours of School Principals According to Teachers' Perception
Authors: BİLGİVAR Orkun Osman , YALÇIN Elif
Published: July 2022

Bu çalışmada, öğretmenlerin algılarına göre okul müdürlerinin paylaşılan liderlik davranışlarının çok boyutlu olarak incelenmesi amaçlanmıştır. Araştırma, nicel ve nitel yöntemlerin bir arada kullanıldığı bir karma yöntem araştırmasıdır. Araştırmada karma araştırma desenlerinden sıralı açımlayıcı desen kullanılmıştır. Nicel araştırma süreci 430 öğretmen ile yürütülmüş ve elde edilen veriler t testi, Anova ve post hoc testleri ile analiz edilmiştir. Nicel veri analizinin sonucunda öğretmen algılarına göre, okul müdürlerinin paylaşılan liderlik davranışlarının düşük düzeyde olduğu; öğretmenlerin cinsiyet ve kıdem değişkenlerinin anlamlı bir farklılık oluşturduğu görülmüştür. Nitel araştırma sürecinde aynı örneklem içinden gönüllü olarak seçilen 20 öğretmen ile paylaşılan liderlik kavramı ve okul müdürlerinin paylaşılan liderlik davranışları bağlamında görüşmeler yapılmış ve elde edilen veriler içerik analizi tekniğinden yararlanarak çözümlenmiştir. Nitel bulgular neticesinde; öğretmenlerin paylaşılan liderlik kavramını, “Yönetim Becerileri”, “Bireysel Farklılıklara Saygı”, “Takım Çalışması ve Dayanışma”, “Motivasyon” ve “Yenilikçilik” olmak üzere beş farklı tema başlığında tanımladığı tespit edilmiştir. Karma araştırma sonucunda elde edilen nicel ve nitel bulgular birleştirildiğinde; öğretmenlerin algılarına göre okul müdürlerinin paylaşılan liderlik davranışlarının düşük olduğu ve okul müdürlerinin paylaşılan liderlik için tanımlanan ilgili beş tema bağlamında davranışlarına dikkat etmeleri durumunda, öğretmen algılarına göre okul müdürlerinin paylaşılan liderlik davranış düzeylerinin yükseleceği sonucuna ulaşılmıştır. Okullarda paylaşılan liderliği ortaya çıkaracak bir örgütsel yapının ve işleyişin hayata geçirilmesi ve okulun tüm paydaşlarını paylaşılan liderlik yaklaşımı doğrultusunda bilgilendirecek çeşitli hizmet içi eğitim seminerlerinin verilmesi önerilmiştir.
An Evaluation on Science Teachers’ Scientific Reasoning Skills
Authors: KOCAGÜL Merve , ÜNAL ÇOBAN Gül
Published: July 2022

Bu çalışmada fen bilimleri öğretmenlerinin, sorgulama sürecinde kullanılan zihinsel beceriler olarak akıl yürütme becerilerini kullanabilme ve bu becerilerin öğretimine yönelik öz yeterlik algılarının durumunu değerlendirmek amaçlanmıştır. Katılımcılar olarak, İzmir iline bağlı merkez ilçelerin resmi ortaokullarında görev yapmakta olan 93 fen bilimleri öğretmeninin belirlenmesinde elverişli örnekleme kullanılmıştır. Çalışma kesitsel tarama türündedir. Katılımcıların akıl yürütme becerilerini kullanabilme yeteneklerini belirleme amacıyla “Fen Bilimleri Öğretmenleri ve Öğretmen Adaylarına Yönelik Akıl Yürütme Becerileri Testi (FBÖAYBT)” ve bu becerilerin öğretimine yönelik öz yeterlik algılarını belirleme amacıyla “Akıl Yürütme Becerileri Öğretimine Yönelik Öz yeterlik Algısı Ölçeği (AYBÖ)” veri toplama aracı olarak kullanılmıştır. Çalışmanın sonunda, fen bilimleri öğretmenlerinin akıl yürütme becerilerini kullanma yeteneği bağlamında ortalamanın üzerinde bir başarıya sahip oldukları bulunmuştur. Detaylı analizler öğretmenlerin en fazla analojik akıl yürütme, en az ise nedensel akıl yürütmede başarılı olduklarını ortaya çıkarmıştır. Bununla birlikte, FBÖAYBT’de yer alan tüm sorulara yalnızca tek bir öğretmen tarafından doğru cevap verilmesi dikkat çekicidir. Akıl yürütme becerileri öğretimine yönelik öz yeterlik algıları bağlamında, öğretmenlerin AYBÖ’nün hem geneli hem alt boyutlarında yüksek öz yeterlik algılarına sahip oldukları bulunmuştur. Detaylı analizler, öğretmenlerin akıl yürütme becerilerine dayalı öğrenme ortamı tasarlamayla ilgili maddelerde en yüksek; akıl yürütme becerileri öğretim yollarıyla ilgili maddelerde en düşük öz yeterlik algısı puanlarına sahip olduklarını göstermiştir.
Eğitsel Sonuç Beklentisi Ölçeği: Lise Öğrencileri Örnekleminde Bir Ölçek Geliştirme Çalışması
Authors: ŞEKER Gürcan , ÇAPRİ Burhan
Published: July 2022

Bu çalışmanın amacı lise öğrencilerinin, aldıkları ya da alacakları eğitimden, kariyer gelişimleri, kariyer karar süreçleri ve akademik/mesleki hedeflerine yönelik sonuç beklentilerini ölçmeyi hedefleyen bir ‘Eğitsel Sonuç Beklentisi Ölçeği’ nin geliştirilmesidir. Araştırmanın verileri açıklayıcı ve doğrulayıcı faktör analizi için iki aşamada ve 9-10-11 ve 12. sınıf düzeylerinde öğrenim gören iki farklı çalışma grubundan elde edilmiştir. Açıklayıcı faktör analizi sonucunda elde edilen iki faktör ve 11 maddeden oluşan bir yapının, doğrulayıcı faktör analizi verileri ile doğrulandığını görülmüştür. Araştırmanın geçerlik çalışmaları kapsamında ayrıca benzer ölçek geçerliği çalışması yapılmış ve çalışma sonucunda elde edilen katsayıların kabul edilebilir sınırlar içerisinde olduğu ortaya konulmuştur. Ölçeğin güvenirlik çalışması kapsamında hesaplanan Cronbach Alfa iç tutarlık katsayılarının .81 ile .87 arasında olduğu görülürken, test-tekrar-test güvenirlik katsayılarının ise .65 ile .79 arasında olduğu görülmüştür. Eğitsel sonuç beklentisi ölçeğinin geliştirilmesine yönelik yapılan çalışma ve analizlerden elde edilen tüm bulgular, lise öğrencilerine yönelik geliştirilen, iki faktör ve 11 maddeden oluşan ölçeğin geçerli ve güvenilir olduğunu ortaya koymaktadır.
Experiences of Classroom Teachers on Mathematics Teaching in the Process of Distance Education
Authors: ERGEN Yusuf , ÖZIŞIK Esranur , BÜLBÜL Yunus
Published: July 2022

Bu araştırmada, uzaktan eğitim sürecinde sınıf öğretmenlerinin matematik öğretimine ilişkin deneyimlerinin belirlenmesi amaçlanmıştır. Nitel araştırma yöntemlerinden fenomenoloji deseninde yürütülen araştırmanın katılımcıları, amaçlı örnekleme yöntemlerinden ölçüt örnekleme yöntemi ile belirlenen 20 sınıf öğretmeninden oluşmaktadır. Araştırmanın verileri, yarı yapılandırılmış görüşme formu aracılığı ile toplanmış ve içerik analizi yöntemi ile analiz edilmiştir. Araştırmada, sınıf öğretmenlerinin uzaktan yürütülen matematik öğretimi sürecinde, ders planının aşamalarına uymadıkları, ölçme ve değerlendirme etkinliklerini sonuç odaklı gerçekleştirdikleri ve öğrencilerin matematik ödevlerini kendi kendilerine yaptıklarından emin olmadıkları sonuçlarına ulaşılmıştır. Bunun yanında, derse devamı ve motivasyonu artırmak için veli ile iletişim kurma, dersi eğlenceli şekilde sürdürme ve oyunlaştırma gibi faaliyetler yaptıkları da belirlenmiştir. Ayrıca, sınıf öğretmenlerinin uzaktan yürütülen matematik derslerini somutlaştıramama ve materyalleri etkili kullanamama gibi problemler yaşadıkları, uzaktan eğitim nedeniyle bazı matematik kazanımlarını anlatmakta zorlandıkları, web araçlarını yeterince kullanamadıkları da araştırmanın sonuçları arasındadır. Araştırmada sınıf öğretmenleri, devam sorunu yaşayan öğrencilerin büyük çoğunluğunun tablet, bilgisayar ve internete ulaşma problemi yaşadıklarını da belirtmişlerdir
Mapping the thickness of sea ice in the Arctic as an example of using data from a ship-based television complex for operational hydrometeorological support of maritime activities
Authors: Afanasyeva E. V. , Serovetnikov S. S. , Alekseeva T. A. , Grishin E. A. , Solodovnik A. A. , Filippov N. A.
Published: July 2022

Sea ice charts produced by the ice services of the world are among the most widely used sources of information about sea ice conditions in the Arctic. The absolute majority of sea ice charts are based on visual expert analysis of satellite imagery accompanied by auxiliary data including ground information from coastal stations and ships navigating the Northern Sea Route (NSR). Ground measurements of sea ice thickness are necessary for validating the results of satellite imagery interpretation. Shipboard observations are highly valuable because, unlike coastal stations, the ships provide information about sea ice cover straight on the navigational routes, not in the coastal areas of land-fast ice, where the thickness values are not fully representative of the ice in the open sea. However, the current system of shipboard observations used by commercial fleets often does not meet the reliability requirements due to the human factor involved in the process of data collection. In the early 2000s, the Arctic and Antarctic Research Institute (AARI) suggested a new methodology for shipboard ice thickness measurement. A ship-based television complex (STC) was developed in order to exclude the human factor and standardize observations. The inaccuracy value was estimated as 3.8 % of the real thickness. By 2018, STC had been upgraded to a new ship-based television meteorological complex (STMC) allowing continuous automatic measurement of ice thickness and many other related hydrometeorological parameters during the entire voyage. The automatic and autonomous operation of the new equipment allows placing it on board the ship without the need for an ice specialist to be permanently present. It means that STMC can be used by commercial fleets, which constantly increase the number of Arc7 ice class vessels they use. For economic reasons, reinforced ice class vessels, whose number is growing, represent the only available infrastructure suitable for the deployment of distributed network providing operational hydrometeorological monitoring on the NSR. A comparison of STC data with AARI ice charts has revealed that real-time transmission of STC data from ships to the ice service office could increase the accuracy of ice charts and, as a consequence, the quality of the entire system of hydrometeorological informational support of maritime activities in the Arctic.
Homoeopathic Medicines of Virginian Witch Hazel: Dosage Forms and Standardisation
Authors: Teryoshina N. S. , Lyakina M. N. , Naumova O. A.
Published: July 2022

According to the authors’ analysis of regulatory documents for homoeopathic medicines of Virginian witch hazel (Hamamelis virginiana L.), there is a need to transform quality assessment approaches and to unify analytical procedures for identification and assay tests.

The aim of the study was to determine approaches to identification and assay of homoeopathic mother tinctures of Virginian witch hazel leaves and bark and medicinal products based on the tinctures.

Materials and methods: in order to select quality evaluation procedures, the authors analysed scientific literature, Russian and foreign pharmacopoeias and regulatory documentation regarding homoeopathic medicines of Witch hazel. The authors performed practical evaluation of the selected procedures based on thin-layer chromatography, spectrophotometry, qualitative reactions, and titrimetry, using samples of homoeopathic mother tinctures of Witch hazel leaves and bark, as well as corresponding homoeopathic medicinal products in various dosage forms.

Results: the authors proposed identification and assay procedures for the studied active pharmaceutical ingredients (APIs) and homoeopathic medicinal products and prepared the drafts of pharmacopoeial monographs Hamamelis virginiana e foliis (Hamamelis, Folium) homoeopathic mother tincture and Hamamelis virginiana (Hamamelis) homoeopathic mother tincture. The unified procedures were included in the draft monographs for homoeopathic medicinal products Hamamelis, homoeopathic drops; Hamamelis D1, homoeopathic ointment; Hamamelis, folium D1, homoeopathic ointment; Hamamelis virginiana e foliis D1, rectal homoeopathic suppositories.

Conclusions: the developed procedures are compatible with the principle of holistic, end-to-end standardisation, as they make it possible to carry out identification tests and assays using the same class of biologically active compounds throughout the whole range of homoeopathic medicines from APIs to finished products. The authors proposed the methodology for assessing homoeopathic medicinal products’ quality, taking into account the degree of dilution of the homoeopathic tinctures used.
Endocrine Disorders Associated with Medicinal Products: Approaches to Preclinical Safety Assessment
Authors: Kryshen K. L. , Faustova N. M. , Makarova M. N. , Makarov V. G.
Published: July 2022

The endocrine system coordinates almost all organs and other systems in vertebrates. In particular, it regulates such important biological functions as metabolism, development, reproduction, and behaviour. To date, a significant amount of information has accumulated on endocrine disorders associated with chemical compounds (endocrine disruptors) used in various fields of human activity. The aim of this study was to evaluate the possibility of preclinical risk assessment for the endocrine function disorders attributable to new medicinal products. Endocrine disruptors are associated with a wide range of adverse events, including developmental problems arising from functional abnormalities of the endocrine system. Endocrine disorders caused by endocrine-disrupting chemicals are characterised by a long latency period between exposure and manifestation of a dysfunction; a nonlinear dose–response relationship; and a linear correlation of damage severity to exposure timing and duration. The chemicals influence the endocrine system through multiple mechanisms, the main of which being the interaction with cellular receptors sensitive to certain hormones and the influence on gene expression, intracellular signalling, and hormone transport, etc. This paper discusses the possibility of using hormone levels as indicators of endocrine disruption and presents the literature and authors’ own data on normal levels of relevant hormones in the blood of animals. An analysis of animal blood hormone levels in preclinical programmes will provide an opportunity to evaluate potential iatrogenic risks.
Влияние этилметилгидроксипиридина сукцината на миогенез in vitro
Authors: Абаленихина Юлия Владимировна , Порошина Мария Олеговна , Рябков Александр Николаевич , Щулькин Алексей Владимирович , Якушева Елена Николаевна
Published: July 2022

В исследовании на клетках линии C2C12 оценивали влияние этилметилгидроксипиридина сукцината (ЭМГПС) на процесс миогенеза. ЭМГПС в концентрации 10 мкМ в течение 7 дней инкубации стимулировал процесс миогенной дифференцировки миобластов С2С12, что проявлялось морфологическими изменениями клеток, а также повышением уровня α-актина, миозина, транскрипционных факторов MyoD (Myogenic determination gene number 1), миогенина, оцененного методом вестерн-блот, в среднем на 71,2 %, p ≤ 0,01. Действие ЭМГПС было сопоставимо с эффектом изолированного сукцината, что свидетельствует о том, что, скорее всего, именно эта часть в его молекуле стимулирует миогенез. Индукция миогенеза в культуре клеток под действием ЭМГПС не связана с изменением уровня транскрипционных факторов HIF 1α (фактор, индуцируемый гипоксией) и PXR (прегнан Х рецептор).
Сравнение эффективности бисопролола и небиволола у пациентов с пароксизмальной фибрилляцией предсердий
Authors: Трегубов Виталий Германович , Шубитидзе Иосиф Зурабович , Еремина Марина Александровна , Трегубова Анна Витальевна
Published: July 2022

Цель исследования состояла в определении и сравнении влияния бисопролола и небиволола на функциональное состояние 60 пациентов с пароксизмальной фибрилляцией предсердий на фоне гипертонической болезни II – III стадий и/или ишемической болезни сердца. Оба препарата в составе комбинированной терапии сопоставимо подавляли аритмию и контролировали артериальную гипертензию. Вместе с тем, небиволол положительно влиял на регуляторно-адаптивный статус, в большей степени повышал толерантность к физической нагрузке и улучшал качество жизни. У пациентов с пароксизмальной фибрилляцией предсердий на фоне гипертонической болезни II – III стадий и/или ишемической болезни сердца в составе комбинированной терапии применение небиволола может быть предпочтительнее, из-за более выраженного положительного влияния на состояние больных, в сравнении с бисопрололом.
Влияние соединений, содержащих 4-гидрокси-3,5-ди-трет-бутилфенильную группировку, на активность митохондриальных ферментов и содержание тау-белка в гиппокампе крыс на экспериментальной модели болезни Альцгеймера
Authors: Поздняков Дмитрий Игоревич , Зацепина Елена Евгеньевна , Арльт Аркадий Вальтерович
Published: July 2022

Изучено влияние шести новых соединений, содержащих 4-гидрокси-3,5-ди-трет-бутилфенильную группировку, на активность аконитазы, цитратсинтазы и α-кетоглутаратдегидрогеназы, а также на концентрацию тау-белка в гиппокампе крыс-самцов линии Вистар в условиях β-амилоид-индуцированной болезни Альцгеймера. В ходе исследования установлено, что применение изучаемых соединений способствовало восстановлению активности анализируемых ферментов в среднем на 84,6 % (p < 0,05), а также снижению содержания тау-белка в ткани гиппокампа, по сравнению с животными без фармакологической поддержки, на 48,9 – 65,6 % (p < 0,05). Следует отметить, что содержание тау-протеина у крыс, получавших исследуемые соединения под шифрами FL1, FL2, FC1, FC2, Pyrm1 и Pyrm2, было меньше, чем у животных, которым вводили L-карнитин, на 29,2 – 52,3 % (p < 0,05). Полученные данные свидетельствуют об актуальности дальнейшего изучения исследуемых соединений, содержащих 4-гидр- окси-3,5-ди-трет-бутилфенильную группировку, как анти-тау нейропротекторных средств, повышающих клеточный метаболизм в условиях патологии.