bluuebunny/crossref_metadata_2025 huggingface dataset:
Gnotobiotic system for selecting microorganisms with biocontrol potential against Fusarium oxysporum f. sp. physali
Authors: Garcia Diana , Dávila Lizeth Lorena , González Adriana , Caro Alejandro , Cotes Alba Marina
Published: April 2021

The cape gooseberry (Physalis peruviana) is a Solanaceae species with enormous economic importance in Colombia; it is the second most exported fruit, after bananas. Vascular wilt caused by Fusarium oxysporum f. sp. physali (Fox) is the most limiting factor of this crop, with losses of up to 80% of production. Biological control is a promising alternative for controlling this pathogen. Bacteria and fungi, originally isolated from potentially suppressive soils of cape gooseberry crops in Nariño, Colombia with different management (organic and conventional), were evaluated as biocontrol agents of Fox using a gnotobiotic model (seedlings cultured under axenic conditions with defined microbial strains). Of the 64 isolated microorganisms, 37.5% (15 bacteria and 9 fungi) were discarded because of toxicological risks and an unknow potential biological control. The remaining 62.5% of the microorganisms, 14 bacteria and 26 fungi, were evaluated to assess their potential as biological control agents against Fox. The gnotobiotic model system evaluated the protection and plant growth promotion characteristics. Response variables were used to group the microorganism using a principal component analysis (PCA), and five clusters were obtained. Cluster number four concentrated the 10 microorganisms (three bacteria and seven fungi) with the highest protection values against Fox, with a positive effect on growth. The isolates were identified as two Bacillus subtilis strains, Rhodococcus sp., Podospora setosa, Debaryomyces vindobonensis, Plectosphaerella plurivora, Acinetobacter rhizosphaerae, Umbelopsis sp. and two strains of Trichoderma koningiopsis. The gnobiotic system offered clear advantages for evaluating and selecting microorganisms with a biological control potential against Fusarium oxysporum f. sp. physalis.
Knowledge and perceptions about the reproductive system by pregnants: A qualitative study
Authors: Kammers Ingridy , Sperandio Fabiana , Sacomori Cinara , Moreira Gessica , Cardoso Fernando
Published: April 2021

Background: To know pregnant’s perceptions and a critical basis attributed to the body from the perspective of the reproductive system. Methods: This is a qualitative study. We used a semi-structured questionnaire with socioeconomic and gynecological-obstetric information, an A4 sheet for graphical representation of the reproductive system and pelvic floor and an interview, questioning the meanings of the reproductive system in the pregnancy context. Then, a qualitative analysis of the interviews was produced. Results: Five categories were identified: recognition began in adolescence, health-disease relationship, process of being pregnant, insight into sexuality, and lack of recognition of its importance in pregnancy. Conclusion: This perception had different meanings and roles in adolescence, changing with pregnancy, becoming a cradle of affection through self-care.
The development of group healing storytelling model in multicultural counselling services in Indonesian schools: Examination of disciplinary cases
Authors: Fatchurahman M. , Setiawan M. A. , Karyanti K.
Published: April 2021

Introduction. Discipline is a form of behaviour reflecting responsibility in a person and is essential to be applied to students. However, in reality, many students commit disciplinary violations at school. Therefore, social care teachers must provide innovative services to eliminate disciplinary violations. One such example is the narrative storytelling model presented in the form of healing stories, which can be applied to develop knowledge, feeling, social skills, and appreciation. Storytelling can play a very helpful role in counselling because stories reflect cultural laws, ethics, as well as in governing daily rules behaviour and guide decision-making.

Aim. The current research is aimed to demonstrate group healing storytelling model in multicultural counselling services in schools for disciplinary case management.

Methodology and research methods. This research methodology is based on the ADDIE (Analysis Design Development Implementation Evaluations) model. The participants of this study were 60 students at Muhammadiyah Palangkaraya Senior High School (Palangkaraya, Indonesia). The research instruments for the verification of group healing storytelling model in multicultural counselling services involved front group discussion (FGD), questionnaires, and Likert scale to examine student discipline data.

Results and scientific novelty. The present research provides group healing storytelling model based in multicultural counselling services by applying aspects of local culture in Indonesia, namely ‘Huma Betang' (local culture in central Kalimantan, Indonesia). The authors developed a narrative storytelling model consisting of objectives and intervention stages. The strengths and weaknesses of this model were analysed. Based on the data analysis, this model can be used to improve disciplinary behaviour. The results of statistical analysis show that disciplinary behaviour has increased after the provision of healing storytelling services.

Practical significance. Based on the research results, the authors recommend this model for disciplinary case handlers. This model is also effective to integrate the components of socio-cultural context in curriculum planning. The present model is easily to accept because it has the uniformity with the culture of counsellee. However, it is limited to a cultural context, so it will be complicated to implement it in a different cultural environment.
Indicios de pastoreo extensivo en el noroeste peninsular durante el dominio suevo
Authors: Pérez Rama Marta , Vaqueiro Rodríguez Marcos , Grandal-d'Anglade Aurora
Published: April 2021

Las condiciones edáficas de Galicia (NW de España), debido al sustrato ácido predominante, dificultan la conservación de los restos arqueozoológicos asociados a los asentamientos humanos. En estos casos, la búsqueda en zonas alternativas, como cuevas y trampas naturales en las zonas de pastoreo, puede aportar información sobre los recursos animales disponibles.Se presenta aquí un estudio de los restos de ganado vacuno doméstico encontrados en Cova da Tara o Tara da Triega (Serra do Courel, Lugo). Con una edad de alrededor de 1500 años, los huesos corresponderían con la época de la dominación sueva del Noroeste peninsular. Estos animales habrían llegado vivos a la cueva, de donde se deduce que deambulaban libremente en los alrededores, lo que señala un tipo de pastoreo extensivo. El desgaste dentario y el estudio de isótopos estables en el colágeno óseo reflejan una alimentación poco abrasiva, probablemente arbustiva, concordando con la de zonas de montaña. La talla media calculada para estos animales es pequeña, similar a la descrita para ganado vacuno prerromano.
El mundo de una mujer llamada Elba hace 9300 años
Authors: Vidal Romaní Juan Ramón , Grandal-d'Anglade Aurora , Vaqueiro Rodríguez Marcos
Published: April 2021

Elba, la que viene de las montañas, ha sido el nombre celta elegido para los restos de una joven a la que sorperendió la muerte viajando con 3 uros hace 9300 años en un camino de montaña entre Courel y Ancares (Galicia, España). El volumen 39 de CLXL presenta los datos morfológicos y cronológicos de la cueva donde se encontró a Elba. También se publica el estudio genético, isotópico y forense de sus restos y una reproducción de su cara y cabeza, ambas obtenidas utilizando las técnicas de restauración habituales en la ciencia forense.
Distribución de la precipitación y la evapotranspiración en territorio argentino de Cuenca del Plata
Authors: Hämmerly Rosana , Paoli Carlos Ubaldo , Duarte Oscar Carlos
Published: April 2021

La planificación y gestión del territorio necesitan un acabado conocimiento de la disponibilidad de los recursos naturales, y el agua es uno de los más importantes. La determinación precisa del balance de agua y el agua disponible para diferentes usos requiere de una red bastante densa de mediciones hidrometeorológicas. La precipitación (P) y la evapotranspiración potencial (ETP) son dos términos del balance hídrico de mayor interés en varias disciplinas, incluida la hidrología, la climatología y la agronomía. Las redes de estaciones meteorológicas proporcionan datos de P y ETP, que son comúnmente usadas para la interpolación. Este trabajo analiza la distribución espacial y temporal de P y ETP en el territorio argentino de Cuenca del Plata. El análisis abarca el período 1970-2010 cuyos datos fueron proporcionados por el Servicio Meteorológico Nacional (SMN), la Subsecretaría de Recursos Hídricos de la Nación (SSRH) y el Instituto Nacional de Tecnología Agropecuaria (INTA). El estudio se realizó tanto a escala anual como mensual. Los datos faltantes se estimaron utilizando métodos convencionales. La pluviometría estaba disponible para 94 estaciones, mientras que la ETP se estimó a partir de datos meteorológicos en 38 estaciones, utilizando el método de Penman-Monteith. Los resultados mostraron tendencias para la distribución espacial y temporal de P y ETP. La precipitación media anual osciló entre 499 mm y 2077 mm. La mayor parte del área estudiada de la cuenca del Plata en Argentina es de planicie o llanuras, donde P muestra una fuerte tendencia a aumentar de este a oeste; sin embargo, al oeste de las llanuras, en la región de los Andes, P aumenta con la altitud. El promedio anual de ETP osciló entre 899 mm y 1719 mm. Generalmente, la ETP disminuye a medida que P aumenta, incluso si no hay una superposición total de los valores máximos y mínimos de estas dos variables. Posteriormente, en la región de Chaco Seco ubicada al oeste de la planicie, la ETP se vuelve más alta que P. El análisis de la variabilidad temporal de la precipitación anual en el período 1970-2010 mostró una clara tendencia creciente desde 1970 hasta 2000, seguida de una modesta tendencia decreciente entre 2000 y 2010. La información obtenida en este trabajo es muy importante para la gestión de los recursos hídricos y la planificación en la asignación del recurso, el modelado hidrológico, la evaluación de la recarga y la programación del riego.
Tobacco Product Access Scenarios Influence Hypothetical Use Behaviors
Authors: White Augustus M. , Ossip Deborah J. , Snell L. Morgan , Li Dongmei , Hoetger Cosima , O'Connor Richard , Lester Rebecca C. , Croft Daniel , Underwood Megan , McIntosh Scott , Breland Alison , Schneller Liane , Cobb Caroline O. , Barnes Andrew J.
Published: April 2021

Objective: In this paper, we characterize how potential policies restricting access to tobacco products may impact use behaviors among adult, past 30-day, smokers and e-cigarette users. Methods: We conducted an online experiment with 820 smokers, e-cigarette users, and
dual users (April 27-June 8, 2020). We randomized participants to one of 4 hypothetical access scenarios: (1) tobacco retail stores open + pharmacies open (TOPO); (2) tobacco stores open but favorite brand unavailable + pharmacies open (TOPO-NFB); (3) tobacco stores closed + pharmacies open
(TCPO); and (4) tobacco stores closed + pharmacies closed (TCPC). Outcomes (measured on 0-100 visual analog scales) included the likelihood of quitting, reducing, switching brands or products, and finding another source of tobacco products. Seemingly unrelated regressions tested for associations
between access scenarios and prospective tobacco use behaviors. Results: Participants in the TCPO and TOPO-NFB scenarios were more likely to reduce use, switch brands/products, and find another source (ps < .001) than those in the TOPO scenario. Dual and flavored product users
were more likely to switch products (ps < .01). Conclusions: When tobacco retailers are closed, tobacco users may be more likely to quit and/or reduce use compared to when retailers are open. However, access restrictions could prompt users to switch tobacco brands/products
or sources.
Modeling the Population Health Impacts of Heated Tobacco Products in Japan
Authors: Camacho Oscar M. , Hill Andrew , Fiebelkorn Stacy , Jones Joshua D. , Prasad Krishna , Proctor Christopher , Murphy James
Published: April 2021

Objective: We evaluated the potential population health impact of launching heated tobacco products (HTP) in Japan. Method: We use a modeling approach to project the effects of HTP use in overall mortality up to 2100 and compare those projections against a baseline scenario
based on smoking rates pre-HTP launch, ie, smoking only. The model was informed using data from publicly available sources and the literature, including population size, yearly deaths, and smoking prevalence with the initial year of 2004, and births and migration from 2004 to 2065. Transitions
between products were estimated from cross-sectional population surveys in Japan. Result: In a worst-case scenario, population health gains would be seen with HTPs risk about 50% lower risk than smoking. Assuming equal risk for dual use and smoking, HTP risk would need to be at least
10% lower than smoking to achieve a population health benefit by 2100. Potential reduction in life-years lost with the introduction of HTPs was 13 million by 2100 compared with smoking only. Conclusions: In credible scenarios, substantial population harm reduction will follow the introduction
of HTPs in Japan.
COMPARATIVE ACTIVITY OF TOTAL POLYPHENOLS AND ANTIOXIDANT COMPOUNDS FROM UNCARIA TOMENTOSA ENHANCED WITH CITRIC ACID
Authors: Roque Borda Cesar Augusto , Katerine Aranda Medina Camila , Felismino Silveira Raiza , Ayleen Bustos Mac-Lean Priscilla , Vacaro de Souza Angela , Ferrari Putti Fernando , Festozo Vicente Eduardo
Published: April 2021

Uncaria tomentosa, a climbing vine notable for containing high concentrations of oxindole alkaloids and phenolic compounds, is commonly used in traditional medicine as an anti-inflammatory and antioxidant agent. Also, the citric acid is a food additive widely used for conservation, due to its low cost. In this way, this study aims to evaluate the content of phenolic compounds from Uncaria tomentosa and investigate its antioxidant activity when citric acid, at different concentrations, is added to the extract. For this purpose, a gradient of citric acid concentrations was established, and the antioxidant profile from a aqueous extracts of the plant leaves and bark was analyzed by Folin-Ciocalteu essay; inhibition of the free radical of 2,2-diphenyl-1-picrylhydrazyl (DPPH); ferric reducing antioxidant power (FRAP), and scavenging capacity of cationic free radicals of 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). The results showed a synergistic effect between citric acid and antioxidant compounds from Uncaria tomentosa, presenting highly statistical significance, the synergistic effect was more efficient in the bark than in the leaves.
Demonstration of the possibilities of reconstructive surgical interventions for closure of the exposed bones of the facial skeleton and cranial vault due to extensive defects of various etiologies
Authors:   Kuban State Medical University, Krasnodar, Russian Federation, Bogdanov S.B. ,   Ochapovsky Research Institute and Regional Hospital # 1, Krasnodar, Russian Federation, Zabunyan G.A. ,   Ochapovsky Research Institute and Regional Hospital # 1, Krasnodar, Russian Federation, Marchenko D.N. ,   Kuban State Medical University, Krasnodar, Russian Federation,   Ochapovsky Research Institute and Regional Hospital # 1, Krasnodar, Russian Federation, Blazhenko A.N. ,   Kuban State Medical University, Krasnodar, Russian Federation, Karakulev A.V. ,   Kuban State Medical University, Krasnodar, Russian Federation,   Ochapovsky Research Institute and Regional Hospital # 1, Krasnodar, Russian Federation, Aladyina V.A. ,   Kuban State Medical University, Krasnodar, Russian Federation
Published: April 2021

Introduction Surgical treatment of patients with tissue defects of the scalp and face is challenging for surgeons. It is an integral part of the social and labor rehabilitation of such patients. Exposure of the skull bones after extensive polyetiological resections creates a difficult task for reconstruction of complete or partial loss of soft tissues of the head. Autologous dermoplasty, simple in its technical implementation, is impractical on the bones of the facial and cerebral skull because insufficient vascularization of the wound bed creates a risk of early rejection of the graft. The aim of the study was development and evaluation of the effectiveness of the method of restoring the integrity of the skin of the head and face inh extensive defects with exposure of the bones of the skull. Materials and methods Аnalysis of the methods and results of reconstructive surgical treatment of three patients with extensive defects in the tissues of the scalp and face at the Research Institute of the Ochapovsky Regional Clinic Hospital No.1 in 2018-2020. Results The immediate result of surgical treatment was a complete restoration of the skin with the maximum possible preservation of underlying deep anatomical structures after a radical one-step removal of non-viable tissues, both soft and bony. Subjectively, the patients were satisfied. The aesthetic result obtained in all cases satisfied both the patients and the surgical team. Conclusion The treatment of extensive defects of the soft tissues of the face and bones of the skull is a doable task, provided certain conditions are met. Removal of the affected tissues with simultaneous plasty of the resulting wound defect with a autologous greater omentum and skin autografts allows one to simultaneously solve the problem of plastic closure of wound defects of such localization. When performing osteonecrectomy of the outer cortical plate of the skull to the bleeding layer, conditions are created for survival of a free skin autograft on the bone.
Evaluation of VDR and PAI allelic genes in patients with avascular necrosis of the femoral head
Authors:   Limited Liability Company ", Volkov E.E. ,   HuangDi Medical Center",   , Moscow, Russian Federation, Goloshchapov A.P. ,   Limited Liability Company "HuangDi Medical Center", Moscow, Russian Federation, Mustafin R.N. ,   Bashkir State Medical University, Ufa, Russian Federation, Nostaeva S.E. ,   Limited Liability Company "HuangDi Medical Center", Moscow, Russian Federation
Published: April 2021

Objective To evaluate the informative value of the carrier status for allelic variations that determine the sensitivity of tissues to calcitriol (VDR) and are involved in familial thrombophilia and hypofibrinolysis (PAI-1) as molecular genetic markers of avascular necrosis of the femoral head (AVNFH). Material and methods A clinical and laboratory study of 300 AVNFH patients, residents of European Russia, was carried out. A comparative analysis of the alleles and genotypes frequency distribution of polymorphisms rs11568820 and rs1544410 of the VDR gene, as well as rs1799889 of the PAI‑1 gene in AVNFH patients was performed. Results AVNFH patients showed a significant increase in the frequencies of the G/G genotype (P = 3.0E‑9) and the G allele (P = 0.05) of the rs11568820 VDR polymorphism (P = 2.10E-08) as compared to controls. The frequency of the A/A genotype of the rs1544410 VDR locus in AVNFH individuals was higher than that in controls (P = 0.05). Discussion Carriers of the genotype G / G A-3731G (Cdx2) of the VDR gene were shown to have a 2.1-fold increased risk of developing AVNFH; carriers of the G allele appeared to have a 2.3-fold increased risk of AVNFH. The findings showed that the carriership of the 5G allele of the polymorphic locus PAI-1 -675 4G > 5G (rs1799889) is detected 1.4 times more often in AVNFH patients than in individuals from the population sample. The risk of developing the pathology is increased 2 times with the carriership of the 5G/5G genotype of this polymorphic locus. Conclusion Carriers of genotypes G/G rs11568820 VDR (allele G), A/A rs1544410 VDR and 5G/5G (allele 5G) at the polymorphic locus rs1799889 PAI-1 have an increased risk of developing AVNFH. This allows the use of the molecular genetic markers in the early diagnosis of AVNFH in individuals who are at greater risk for the disease.
Oportunidades y retos para potenciar el liderazgo femenino en la región CID
Authors: Martínez André
Published: April 2021

El liderazgo femenino, entendido como la participación de las mujeres en la toma de decisiones económicas, se ha venido incrementando levemente en los últimos años, tanto a nivel mundial como en la región latinoamericana. No obstante, aún existe una brecha de liderazgo considerable con respecto a los hombres. Por ejemplo, en la región CID, las mujeres apenas ocupan menos de una cuarta parte de los puestos de gerencia principal en las empresas (22.4%) y tan solo en un 35% de las firmas, las mujeres participan en las juntas directivas. Evidencia empírica, usando técnicas econométricas, hallada en la región sugiere que la probabilidad de que las mujeres dirijan empresas se relaciona positivamente con la presencia de mujeres entre los propietarios, y negativamente con las firmas sean grandes o se dediquen a actividades en el subsector de metales, maquinaria y equipos. Utilizando el método de descomposición de Oaxaca-Blinder, se encuentra que para los países CID, existe una brecha total de 30% en la productividad de las firmas dirigidas por las mujeres con relación a las gerenciadas por hombres, lo cual está asociado a una menor participación de capital extranjero, menor gasto en seguridad, menor formalización desde el inicio de las operaciones de la firma, menor inversión en capital humano (capacitación), y menor edad de las empresas.
Prognostic Significance of Clinical Profile, Biochemical Markers with Special Reference to Serum Lactate Dehydrogenase (LDH) Level in Sepsis and Its Correlation with Survival of the Patient
Authors: Narayanan Pradeep , Ambedkar Narendran , Senthaizhselvan Prakash , Augustine Sabu
Published: April 2021

BACKGROUND Sepsis is a potentially life threatening medical emergency. It should be diagnosed at the earliest and treated effectively to prevent mortality. Therefore, there is a need for parameters which are simple, reliable and cost effective which help in predicting the prognosis and help in managing the patient with sepsis more efficaciously. METHODS A total of seventy patients, 42 male and 28 female patients, over a period of one year, who fulfilled the inclusion and exclusion criteria was included in the study. In this study various clinical variables and biochemical markers including serum lactate dehydrogenase (LDH) were compared among survivor and non–survivor groups and analysed. RESULTS In this study out of 70 patients, 36 patients [51.4 %] expired. Various clinical variables and biochemical markers including serum LDH [on day 1 & day 3], were compared among survivor and non–survivor groups and analysed. Pulse rate, mean arterial pressure (MAP), total leucocyte count, renal function test (RFT), liver function test (LFT), day 3 LDH levels and requirement of ventilator support showed statistically significant difference among the survivor and non-survivor groups. CONCLUSIONS Despite the recent medical advances, sepsis is a multiorgan disease with significant mortality. Hence, we need simple and effective parameters which are essential in assessing the prognosis and in guiding the treatment protocols. This study focused on simple clinical and biochemical parameters with special reference to LDH, which helped us in predicting the mortality. KEYWORDS Markers, Serum LDH, Sepsis, Survival
Magnetic Resonance Imaging in the Evaluation and Characterisation of Sellar and Juxtasellar Lesions
Authors: B Kaushal , H.M Chandrashekar , C.S Shobhalakshmi , K.R Vijakumar
Published: April 2021

BACKGROUND The sellar and juxtasellar region is a complex area where varied pathologies can occur. Differentiation among various pathologies may not always be easy, since many of these lesions mimic pituitary adenomas on clinical presentation, endocrinologic and radiologic examinations. The study intends to describe the imaging characteristics of the spectrum of pathological conditions affecting these regions using magnetic resonance imaging (MRI). METHODS The main source of data for the study were patients from hospitals attached to Bangalore Medical College and Research Institute, Bengaluru viz. Victoria Hospital, Bowring and Lady Curzon Hospital and Vani Vilas Hospital. Patients with suspected sellar and juxtasellar pathology on clinical examination referred to the Department of Radiodiagnosis from November 2017 to May 2019 underwent MRI study using Siemens 1.5-T Magnetom Avanto MR system. Magnetic resonance imaging was done in all patients according to the pituitary protocol. RESULTS Among the 50 patients, there were 16 males and 34 females. Most of the patients were in the third to fifth decade of life. The various abnormalities on MRI included neoplastic (68 %), malformative (8 %), vascular (6 %), granulomatous, infectious and inflammatory (18 %) lesions. Pituitary adenomas (46 %) were the most common lesions in sellar and juxtasellar regions, followed by tuberculosis (10 %), craniopharyngioma (8 %), Rathke's cleft cyst (6 %), meningioma (6 %), internal carotid artery (ICA) aneurysm (4 %), epidermoid (2 %) and miscellaneous lesions. CONCLUSIONS MR imaging characteristics were sufficiently distinct to allow various sellar and juxtasellar pathologies to be differentiated from each other. The spectrum of MRI findings were related to neoplastic, malformative, infectious, inflammatory, granulomatous and vascular causes. Our study observed that MRI with appropriate imaging protocols is the essential imaging modality in evaluation of sellar and juxtasellar lesions. KEYWORDS Pituitary, Sellar, Juxtasellar, Magnetic Resonance Imaging
Residual and Direct Contact Toxicities of Crude Extracts and Essential Oils from Acorus calamus L. (Acoraceae) Rhizomes against Cassava Red Mites (Acari: Tetranychidae)
Authors: Janlaor Kitiya , Auamcharoen Wanida
Published: April 2021

Tetranychus truncatus Ehara (Acari: Tetranychidae) is a serious economic pest of many plants in Thailand and other countries. The use of plant extracts is an alternative to conventional synthetic pesticides for controlling mite pests. This study was conducted to evaluate the residual and direct contact toxicities of crude extracts and essential oils obtained from Acorus calamus L. (Acoraceae) rhizomes against T. truncatus eggs and adult females under laboratory conditions. Residual toxicity was assayed by applying compounds on leaf discs and then releasing adult female mites on the discs; direct contact toxicity was assayed by spraying the compounds on eggs and adult females. In residual assays, a 10% (v/v) concentration of essential oils extracted from fresh A. calamus rhizomes caused 73.8% mortality of T. truncatus adults, while treatment with oils from dried rhizomes caused 91.8% mortality of adults. In direct-contact toxicity assays, essential oils from fresh rhizomes reduced egg hatch by 96.3% at 5% (v/v) concentration and 100.0% at 10%. Oils extracted from dried rhizomes reduced egg hatch by 28.8% at 5% and 91.8% at 10%. The respective median lethal concentrations (LC50s) were 2.18% and 5.91%, based on cumulative mortality at 7 d after treatment. Methylene chloride extracts from fresh and dried rhizomes (individual extraction method) caused a cumulative adult mite mortality of 100% and 91.4% at 5% (v/v) concentration, with LC50s of 1.31% and 2.52%. Based upon our results, essential oils and methylene chloride extracts from A. calamus rhizomes appear as suitable botanical acaricides for further development for the management of T. truncatus.
Association of rs3135500 and rs3135499 Polymorphisms in the MicroRNAbinding Site of Nucleotide-binding Oligomerization Domain 2 (NOD2) Gene with Susceptibility to Rheumatoid Arthritis
Authors: Ehtesham Naeim , Alani Behrang , Mortazavi Deniz , Azhdari Sara , Kenarangi Taiebe , Esmaeilzadeh Emran , Pakzad Bahram
Published: April 2021

The nucleotide-binding oligomerization domain 2 (NOD2) is the key regulator of inflammatory responses and has been involved in the pathogenesis of rheumatoid arthritis (RA). Laboratory and in silico evaluations have demonstrated that some polymorphisms in 3ˊUTR of NOD2 gene could influence the secondary structure of this region and similarly thermodynamic features of hybridization site and finally deregulate the expression of NOD2. In the current study, for the first time, we evaluated the possible association between single nucleotide polymorphisms (SNPs) rs3135500 and rs3135499 in the NOD2 gene with RA risk in the Iranian population. One hundred and fifteen patients with RA and 120 healthy subjects were recruited in this case-control study. Genotyping of rs3135500 and rs3135499 polymorphisms were accomplished using the real‑time polymerase chain reaction high resolution melting (HRM) method. We found a substantial association of AA and AG genotypes in rs3135500 with the risk of RA (AA vs GG; OR=5.547; 95%CI [2.564-11.999]; p<0.001 and AG vs GG; OR=2.179; 95%CI [1.145-4.147]; p=0.017). Moreover, in the patient group, there was a significant relationship between the increased concentration of erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) with rs3135500 (A allele) (p<0.05). However, there were no important associations between rs3135499 with the risk of RA (p>0.05). However, we found a noteworthy association of the C allele in rs3135499 with an increased level of CRP in patients (p>0.05). Our findings propose a considerable association between NOD2 polymorphisms with increased risk of RA and disease activity.
Distribution of Myeloid and Plasmacytoid Dendritic Cell Subpopulations in Peripheral Blood of Hyperprolactinemic Women
Authors: Raeesi Nejad Fatemeh , Mohammadi Mohammad Mahdi , Sanjari Mojgan , Malkpour Afshar Reza , Jafari Elham
Published: April 2021

Dendritic cells (DCs) play key roles in regulating the immune response using the specialized function of processing and presenting antigens. Prolactin (PRL), a hormone produced by the pituitary gland, participates in DC maturation and function. The present study was aimed to determine the frequencies of peripheral blood DC subpopulations of myeloid DC (MDC) and plasmacytoid DC (PDC) in hyperprolactinemic (HPRL) women compared to normal healthy volunteers. This study was conducted on 70 women, including 35 HPRL patients and 35 matched healthy controls, whose PRL serum levels were in the normal range (lower than 25 ng/mL). Serum thyroid-stimulating hormone (TSH) levels were measured in both groups as an indicator of normal thyroid function. The electrochemiluminescence immunoassay method was applied to measure the serum levels of TSH and PRL. The frequencies of MDC and PDC in the peripheral blood samples of both groups were determined by flow cytometry. The mean serum PRL levels in the HPRL patients and healthy individuals were 46.41±21.96 and 13.75±11.19, respectively (p<0.0001); however TSH levels in both groups were similar and within the normal range (0.4–4.5 mIU/mL) (p=0.2). The frequencies of both MDC and PDC subpopulations in the peripheral blood of HPRL patients were significantly lower than they were in the healthy controls. However, the ratio of MDCs/PDCs in HPRL patients was not significantly different between the two groups (p=0.8). Our study revealed that an increased level of serum PRL may lead to a reduction in the number of MDC and PDC subpopulations. These results could help clarify the complex relationship between the immune system and the neuroendocrine axis and may be of potential use in understanding the pathogenesis of endocrine and immune disorders.
Relationship between Breast Cancer and Cardiac Myxoma
Authors: Alizadehasl Azin , Rahbar Zohreh
Published: April 2021

The article's abstract is not available.
Medication Reconciliation and Drug–Drug Interactions: An Old Process with a New Approach
Authors: Ala Shahram , Tonkaboni Sufia , Bazi Aliyeh , Salehifar Ebrahim
Published: April 2021

Background: The occurrence of drug–drug interactions (DDIs) and insufficient attention to medication reconciliation is one of the important challenges of pharmacotherapy in hospitalized patients. The aim of this study was to determine the extent of drug–drug interactions in patients based on medication reconciliation strategy.
Methods: This descriptive cross-sectional study was performed for six months in patients admitted to Imam Reza Hospital in Amol, North of Iran. The data were obtained by using a medication reconciliation tool through a random sampling of patients admitted in Hospital wards from May 2014 until October 2014. A total of 200 patients were enrolled in the study. All patients had a history of medication use before admission. The drug interactions have been checked according to Drug Interaction Facts between newly prescribed drug and medication patient using before admission. The number and frequency of data were summarized by SPSS21 statistical software.
Results: Major and Moderate DDIs were found in 7.5% and 64% of prescriptions. The most frequent DDIs were seen in those who were taking psychiatric drugs (33%) and cardiovascular drugs (30%). Most DDIs occurred among women over 60 years of age. The most frequently occurring DDIs was pharmacokinetics interaction between clopidogrel and atorvastatin (n=9). Other frequent interactions were between ceftriaxone and heparin (n=8) and metoprolol and insulin (n=3).
Conclusion: This study showed a high rate of drug interactions and especially confirms the importance of medication reconciliation in providing a comprehensive drug history and exploring drug interactions.
Perception of the Space of Bondage in the Poetic Works by A.I. Solzhenitsyn
Authors: Glukhova Nadezhda I.
Published: April 2021

The article examines the psychological situations in which A.I. Solzhenitsyn puts the lyric character of the poem “Dorozhenka” and poems in order to reflect the degree of his freedom and lack of freedom in the surrounding space. The perception of places of captivity is conveyed by the author not only through images of a prison cell, a prisoner transport vehicle, a prisoner train car, a barrack, a labor camp zone, but also through a generalization – the territory of the country surrounded by barbed wire. The space of enslavement appears in the form of concentric circles: the character himself is in the center, the next circle is a prison cell or a barrack, further is the GULAG zone and all of Russia, which is thought of as a large labor camp. The lack of freedom becomes the inner state of the lyric character, but at the same time it is aimed at achieving freedom of the spirit. According to Solzhenitsyn’s views, one can feel psychologically free only in the labor camp, having lost everything that is dear in ordinary life, and therefore losing fear, because, being out of prison, a person is crushed by suspicion and Stalin’s ideology, he is constantly under the threat of arrest.
V. Ya. Bryusov and N.Ya Bryusova on the Pages of the Weekly «Music»
Authors: Gevorkyan Armen V.
Published: April 2021

At the end of November 1910 a new musical weekly «Music» was founded, the editor-publisher of which was V.V. Derzhanovsky. He allotted a significant place on the pages of the publication to the creativity of Russian Symbolists: there were published announcements and reviews of the Symbolists published in the publishing houses «Scorpio», “Musaget”, “Grif”, their poetic texts. Of particular interest to the publisher of “Music” was the literary work of V.Ya. Bryusov, as well as the activities of his closest circle, in particular, the poet’s sister, N. Ya. Bryusova.
Ethnocultural Competence Development in Teaching the English Language to Kalmyk High School Students
Authors: Basanova Tatiana V.
Published: April 2021

Developing ethnocultural competence by teaching a foreign language is considered to be a contribution to ethnic identity development that is the aim of ethnic socialization process. The present article describes the content of the English language teaching in the process of ethnocultural competence development. Thematic and procedural aspects are distinguished. Each one has a complex nature and contributes to profound considering ethnic related information by Kalmyk students at high school.
Regional Component in Teaching Russian as a Foreign Language (Republic Sakha (Yakutia))
Authors: Kirillina Kristina P.
Published: April 2021

The regional component in teaching foreigners the Russian language is becoming increasingly important in the modern educational space. The article presents the methodology of teaching foreign students from China and South Korea to Russian phonetics using vargan, the national instrument of the Yakutia. The methodological basis of the study includes comparison, observation, study and summary of personal experience in a foreign audience. The indicated methods made it possible to prove the musical instrument vargan has a wide potential in teaching the phonetics of foreign students in the Russian language classes. It removes language difficulties, corrects the production of sounds, promotes the development of musical ear and motivation to learn the Russian language, relieve fatigue, and overcome the intercultural barrier. During the analysis of the main phonetic difficulties of students from China and South Korea, similar and distinctive features of the sound system of the native and Russian languages were highlighted, a system of training exercises was proposed that would interest students in pronunciation, practicing and correcting specific unpronounceable Russian sounds. Prospects for the study are the further use of the harbor in the classroom with students from countries such as Japan, Vietnam, India, Italy, Hungary, France, which have a similar musical instrument.
“To Interpret the Appearance of Peter from the Laws the Idea Development…” – the Reflections about Peter the Great in A. I. Herzen’s Publicism
Authors: Kruglikova Olga S.
Published: April 2021

Herzen’s historiosophical concept in general and his attitude to the transformations of the first Russian emperor in particular were largely determined by the specifics of the Russian public dialogue in the second third of the 19th century. A.I. Herzen’s understanding of the historical role of Peter the Great changed in the course of the evolution of his historiosophical concept. From the admiration for the monarch’s transformative energy and the commitment for the Europe’s ideal through the humanistic criticism of absolutism and the skepticism towards European values, Herzen came to recognize Peter’s activities as a catalyst of social discontent and ferment, which in the future will lead Russia to a revolution of a special type, different from the bourgeois revolutions of the European model.
Znaczenie definicji biedy w wyznaczaniu granicy ubóstwa
Authors: Chmielewski Piotr
Published: April 2021

Artykuł ten ma na celu zaprezentowanie klasycznych sposobów wyznaczania granicy ubóstwa oraz porównanie ich z szerszymi koncepcjami wielowymiarowego zagadnienia, którym jest bieda i wykluczenie społeczne. Wybór konkretnej definicji oraz sposobu pojmowania ubóstwa ma fundamentalne znaczenie dla procesu eradykacji zjawiska biedy oraz przekłada się na praktyczne działania implikowane przez politykę rozwojową. Niemniej jednak dominujące obecnie sposoby wyznaczania granicy ubóstwa podchodzą do tego zagadnienia w sposób zbyt redukcjonistyczny. Autor artykułu stara się wskazać alternatywne podejścia do koncepcji dobrobytu i rozwoju, które mogą wywrzeć pozytywny wpływ na strategie walki z ubóstwem.
CARMEN GROUP EM ODETE INVENTA O MAR – UM EXPERIMENTO: REFLEXÕES A PARTIR DE UM PROCESSO TEATRAL ON-LINE
Authors: Gonçalves Michelle Bocchi , Costa Shéurily Santos da
Published: April 2021

O presente texto busca refletir sobre o processo criativo para Odete inventa o mar – Um experimento, espetáculo do Carmen Group, realizado em meio a pandemia de Covid-19. O trabalho, que parte do texto homônimo, de autoria de Sônia Machado de Azevedo, foi selecionado para o Das Janelas Festival de Teatro On-Line, promovido pelo curso de Teatro da FURB – Universidade Regional de Blumenau, que aconteceu em novembro de 2020. Entre os aspectos abordados no artigo, destaca-se a busca pela compreensão do que é fazer teatro no universo on-line, especialmente no que se refere ao funcionamento discursivo de processos cênicos que implicam corpo e presença na esfera virtual.
POLÍTICA DE TAMBORES: TRANSVERSALIDADES QUE MOVIMENTAM UM COLETIVO DE CRIAÇÃO EM MEIO À PANDEMIA DE COVID-19
Authors: Garlet Francieli Regina , Cardonetti Vivien Kelling , Mossi Cristian Poletti , Oliveira Marilda Oliveira de
Published: April 2021

Apresentam-se, neste ensaio, indagações e experimentações em forma de escritas e leituras com imagens de um coletivo de criação que se dedica há algum tempo a produzir academicamente com os campos da educação, da arte e da filosofia. Opera-se com os conceitos de percussão e de política de tambores, empreendidos por Basbaum (2017), com a noção de coletivo, abordada por Escóssia (2009) e Escóssia e Kastrup (2005), bem como com a noção de encontro, proposta por Deleuze e Parnet (1998). Do ponto de vista metodológico, aposta-se na noção de transversalidade (GUATTARI, 2004), agenciada por quatro pares de mãos, em revezamento. Buscam-se novas sonoridades, harmonias e melodias na produção científica, em meio a um território traçado entre leituras e escritas com imagens que, na composição deste ensaio, é atravessado também por sons e ruídos de um cotidiano acionado pelo confinamento físico provocado pela pandemia de Covid-19.
NA SEARA DA PANDEMIA: PROCESSOS DE CRIAÇÃO QUE GERMINARAM E FRUTIFICARAM NO DECORRER DO ENSINO REMOTO
Authors: Born Patriciane , Pinheiro Jéssica , Rhoden Sandra
Published: April 2021

Este ensaio se configura como um relato de experiências em torno das metodologias utilizadas pelas professoras da área de Artes Visuais da FUNDARTE em tempos de pandemia. Produzido sob a forma de fragmentos, apresentamos o Curso de Iniciação às Artes e o Curso Básico de Artes Visuais com seus respectivos módulos, descrevendo a maneira que cada docente enfrentou os desafios propostos pelo ensino remoto para dar continuidade aos processos de criação dos alunos em contextos diversificados. Apresentado como escrita coletiva, o texto constitui-se de escolhas individuais em torno da metáfora do plantio, apoiando-se em referenciais teóricos diversos. Por questões éticas, a voz dos alunos será identificada por pseudônimos relacionados à figura de linguagem que permeia a escrita.
CORPO-EXPERIMENTAÇÕES: A COMPOSIÇÃO DE PRÁTICAS CORPORAIS NA EDUCAÇÃO INFANTIL EM MEIO AO DISTANCIAMENTO SOCIAL
Authors: Raymundo Diewerson do Nascimento , Pacheco Eduardo Guedes
Published: April 2021

Este artigo propõe-se a revisitar algumas práticas corporais desenvolvidas entre 2019 e 2020 com crianças entre 3 e 5 anos de uma escola privada de Educação Infantil de Viamão/RS.  Pelo viés da Arte-Educação em diálogo constante com a Pedagogia e a Filosofia, provocou-se um modo de problematizar, pensar e criar corporalmente mobilizado por obras de artes visuais, por grafismos indígenas, por sonoridades e gestualidades. A cartografia foi a metodologia utilizada a partir das colaborações de Gilles Deleuze e Félix Guattari, Eduardo Passos e Virgínia Kastrup. As corpo-experimentações criadas colaboraram para proposição de práticas pedagógicas mais desafiadoras às crianças mesmo durante o distanciamento social e ensino remoto.
Efficacité d’un traitement intravaginal à base de progestérone chez des vaches croisées  Bos indicus  x  Bos taurus
Authors: Kouamo Justin , Iliassou Iliassou , Hayatou Souley , Ngu Ngwa Victor , Teitsa Zangue Camille
Published: April 2021

L’étude a eu pour objectif d’évaluer l’efficacité d’un traitement combiné à base de progestérone intravaginale sur l’induction de l’oestrus de femelles croisées au Cameroun. Un total de 116 vaches Goudali (Bos indicus) x Charolaises (Bos taurus) ayant mis bas au moins une fois, sans antécédent pathologique, avec une note d’état corporel supérieure à 2, ont été sélectionnées dans des élevages du département de la Vina (arrondissement de Nyambaka). Elles ont été rassemblées dans un ranch et réparties en lots de 10 animaux. Le protocole d’induction et de synchronisation des chaleurs a consisté en la pose d’un dispositif intravaginal à base de progestérone (Prid Delta) pendant huit à neuf jours. Vingt-quatre heures avant son retrait, une injection de cinq millilitres de prostaglandine F2alpha (Dinoprost, Enzaprost) a été administrée. Au moment du retrait, 500 UI de gonadotropine chorionique équine ont été injectées. Cinquante-six heures après le retrait, l’insémination a été effectuée à heure fixe avec de la semence de taureaux Gyr et Brahman. Les taux d’induction de l’oestrus et de synchronisation, de rétention du dispositif intravaginal, de gravidité en première insémination, de fécondité, et d’avortement ont été respectivement de 100 %, 100 %, 56,0 %, 51,7 %, et 4,3 % (en % des vaches traitées). Le Prid Delta s’est révélé efficace pour l’induction des chaleurs et l’obtention de gravidités chez les vaches Goudali x Charolaises.
THE VARIANT ANATOMY OF THE CELIAC TRUNK AND ITS BRANCHES IN ADULT MEN AND WOMEN WITH VARIOUS BODY SHAPE
Authors: Gayvoronsky Ivan V. , Bykov Petr M. , Gayvoronskaya Mariya G. , Sinenchenko Georgy I. , Semenova Anastasia A.
Published: April 2021

In connection with the rapid development of endovascular surgery and the increasing number of minimally invasive surgeries there is a need for a detailed study of variants of the architectonic and topographic and anatomical characteristics of extraorganic blood vessels. The purpose of the study was to study the variant anatomy of the celiac trunk and its branches in adult men and women with different shapes of body. The analysis of 2300 computer tomograms of the abdominal aorta and its unpaired branches of adult men and women in age 25-75 years with a different body type was made. According to the value of the Pinier index, were dedicated asthenic, normosthenic and hypersthenic forms of the physique. It is established that the cases of a typical classic variant of celiac trunk trifurcation in men is observed only in 35% of cases, and in women – in 41.2%, with an atypical variant of its division was observed significantly more often (in 65 and 58,8%, respectively). It is shown that regardless of gender and the shape of the body at Pinier index in all studied groups, the incidence of typical branching of the celiac trunk varies from 32.1 to 49.4%, and the frequency of atypical variant is an average of 62.1%. Among atypical variants of division of the celiac trunk quadrifurcation occurs more often. Thus, the frequency of most of the variants of the celiac trunk showed significant differences depending on gender and body type. Knowledge of variant anatomy of the celiac trunk will be may significantly increase the quality of preoperative diagnosis in surgery on the celiac trunk and its branches, and exclude iatrogenic damage of these vessels.