bluuebunny/crossref_metadata_2025 huggingface dataset:
Polikistik Over Sendromuna Multidisipliner Yaklaşım
Authors: Elgün Tuğba
Published: March 2023

Polikistik over sendromu (PKOS), kadınların üreme fonksiyonlarını etkileyen, oligoovülasyon ve hiperandrojenizm ile karakterize, yüksek prevalansa (%5-10) sahip heterojen bir endokrin-metabolik disfonksiyondur. Etiyolojisi belirsizdir ve patofizyolojisinde ve uzun vadeli metabolik sonuçlarında (metabolik sendromun erken gelişimi, tip 2 diyabet ve kardiyovasküler hastalık gibi) insülin direnci (IR) ile yakından ilişkilidir. PKOS'un ne olduğunu daha iyi anlamak için PKOS'un nasıl tanımlandığını ve kategorize edildiğini bilmek önemlidir. PKOS ile benzerlik gösteren belirti ve semptomlara sahip; hiperprolaktinemi, klasik olmayan konjenital adrenal hiperplazi ve Cushing sendromu gibi spesifik bozukluklar, doğru bir PKOS teşhisi için ekarte edilmelidir. Klinik bulguların PKOS düşündürdüğü olgularda biyokimyasal testlerle ve ultrasonografik bulgularla desteklenebilir. Hastaların laboratuvar değerlendirmesinde hiperandrojenemi gözlenir. PKOS’da en sık görülen hiperandrojenizm bulgusu hirsutizmdir. Bu bulgulara ek olarak LH ve LH/FSH düzeylerinde artma gözlemlenebilir. Düzensiz adet dönemleri olan kadınların PKOS olma ihtimali yaklaşık %91'dir. Kronik anovülatuar infertilitenin en sık nedeni olan PKOS, diyabet, dislipidemi, kardiyovasküler hastalık ve endometriyal karsinoma gibi sağlık riskleri taşıması nedeniyle son zamanlarda bir halk sağlığı problemi olarak ön plana çıkmaktadır. PKOS’un teşhis zorlukları nedeniyle, birinci basamak sağlık hizmeti sağlayıcıları, jinekologlar ve endokrinoloğun birlikte değerlendirilmesi önerilebilir. PKOS’un yönetiminde multidisipliner yaklaşımın önemi ise her geçen gün artmaktadır.
Sitrülin Desteğinin Hastalıklar ile İlişkisi: Kanser ve Metabolik Hastalıklar
Authors: Akgül Işık Ayşe
Published: March 2023

Biyosentez ve metabolik yolu henüz tam olarak aydınlatılmamış ve insan metabolizmasında da önemli bir aminoasit/protein olan sitrülin, glutamin metabolizmasının son ürünü ve arginin metaboliti olarak bilinmektedir. Bilinen en zengin sitrülin kaynağı karpuzdur ve bu amino asidin kuraklık toleransında önemli bir role sahip olduğu düşünülmektedir. Sitrülinin metabolize edilmesine ilişkin yolaklar ile ilgili muhtemel bazı mekanizmalar açıklanmıştır ve bu yolaklar üzerinden metabolizmadaki önemi ve yeri anlaşılmaya çalışılmaktadır. Ancak son derece karmaşık olan ilişkiler yumağını açıklayabilmek için detaylı verilere ihtiyaç duyulmaktadır. Aynı zamanda destek ürünü olarak alınan sitrülinin hastalıklar üzerine etkisi de bulunmaktadır. Bu etkilerden en çok bilineni ise kanser ve metabolik hastalıklar üzerinedir. Redoks dengesizliği oksidatif bozukluklarla güçlü bir şekilde ilişkili olabileceğinden, diyet antioksidanları birçok insan hastalığını (kanser, ateroskleroz, inme, nörodejenerasyon ve diyabet) önlemede araçsal bir role sahiptir. Bununla ilgili olarak iNOS, üç NOS sınıfından biridir ve belirli kanser türlerinde bağışıklık tepkilerine katkıda bulunan en güçlü NO üreticisidir. Diyabetik hastalarda antioksidan ve hipolipidemik etkilerine ilişkin çalışmaların az olmasına rağmen, CIT ve karpuz ekstraktının diabetes mellitusta glisemik durumu ve inflamasyonu yararlı bir şekilde etkileyebileceği sonucuna varılmıştır.
Kanser Hastalığı ve Rehabilitasyonu
Authors: Çoban Fahriye , Binici Gülnaz
Published: March 2023

Kanser bir organ veya dokudaki hücrelerin düzensiz ve kontrolsüz olarak bölünüp çoğalması sonucu ile oluşan tümörlere denir. Genel anlamda ise kanser vücudumuzun çeşitli bölgelerindeki hücrelerin kontrolsüz çoğalması ile normalde olmayan bir oluşum meydana getirirler. Bu yeni ve ekstra hücreler durmadan bölünerek tümör adı verilen kitleleri oluşturmaktadır. Kanser, metastaz adı verilen bir süreçle vücuda yayılır. Kanser hücreleri orijinal konumlarından ayrılarak kan veya lenf sisteminden geçerek vücudun diğer bölgelerinde yeni tümörler oluştururlar. Kanser metastazları en yaygın olarak kemiklerde, karaciğerde veya akciğerlerde bulunur. Kanser tedavisinde genel olarak ve en yaygın kullanılan tedavi yöntemlerinden immünoterapi, radyoterapi, kemoterapi ve cerrahi tedavi uygulanmaktadır. Bu tedavilerin hastayı etkileyebilecek yan etkileri olmakla beraber koruyucu ve restoratif evresinde büyük öneme sahiptir. Kansere sahip bireylerde bağımsızlığı ve fonksiyonel kapasiteyi artırmak ve yaşam kalitesini iyileştirmek için kanser rehabilitasyonu da önemli bir yere sahiptir. Kanser Rehabilitasyonu hem sağlık bakımı maliyeti açısından hem de kansere yakalanma riskini azaltmaktadır. Birçok Kanser Rehabilitasyon programı, lenfödem, üst ekstremite fonksiyonel bozukluğu, yürüme ve denge disfonksiyonu gibi spesifik hasta ihtiyaçlarına yönelik hizmetler sunsa da, genel olarak fonksiyonel kapasiteyi artırma, büyük kas gruplarını kuvvetlendirme, ağrıyı azaltmak, esneklik ve dengeyi artırarak bağımsızlık seviyesini artırmaya yöneliktir.
Sağlık Kurumlarında Tıbbi Dokümantasyonun Önemi
Authors: Turaç İlkay Sevinç
Published: March 2023

Tıbbi dokümantasyonlar hem hastaya hem de kuruma ait verilerin saklanması ve korunması hususunda sağlık kurumlarında önemli bir yer tutmaktadır. Etkin bir şekilde tutulan tıbbi kayıtlar hasta ve hasta yakınlarına kaliteli ve güvenli bir sağlık hizmet sunumu sağlarken aynı zamanda kurum profesyonelliğini de ortaya koymaktadır. Bir sağlık kurumunun verilen sağlık bakımını optimal düzeye getirmesi ve kaliteli sağlık hizmeti sunabilmesi için etkin bir tıbbi dokümantasyon sistemine ihtiyacı vardır. Bu çalışma, tıbbi dokümantasyonun sağlık kurumları içerisindeki önemini vurgulayarak daha kaliteli ve etkin sağlık hizmetlerine ulaşılması için neler yapılması gerektiğini araştırmak amacıyla tasarlanmıştır. Çalışmada tıbbi dokümantasyonun gelişim süreci anlatılmış, verilen eğitimler ile tutulması gereken tıbbi kayıtlar hakkında bilgi verilmiştir. Tıbbi dokümantasyonun elektronik ortamda düzenlenmesinin önemi ve elektronik tıbbi kayıt sistemi anlatılmış, sağlık kurumlarında kullanılan elektronik tıbbi kayıt sisteminin avantajlar ve dezavantajlarının neler olduğu tartışılmıştır. Literatür taraması sonucunda tıbbi dokümantasyonun hangi açılardan sağlık kurumlarını etkilediği ve daha etkin ve kaliteli sağlık hizmetleri alımı için neler yapılması gerektiği tartışılmıştır.
Çevre Sağlığı ve Tıbbi Atık Yönetimi
Authors: Işık Seda Sibel , Öztürk Çopur Ebru
Published: March 2023

Bir organizmayı etkileyen ortam ve koşulların tümüne çevre denmektedir. Tüm canlılar yaşamlarını sürdürebilmek için çevre ile etkileşim halindedir. Bu etkileşim çevre sağlığını ve atık yönetimini gündeme getirmektedir. Gelişen teknoloji, hızlı nüfus artışı, tüketim taleplerinin değişmesi ve tedavi edici sağlık hizmetlerindeki artış sağlık kurumlarında tıbbi atık yükünün artmasına sebep olmuştur. Sağlık kuruluşlarında oluşan atıklar evsel nitelikli atıklar, tıbbi atıklar, tehlikeli atıklar ve radyoaktif atıklar şeklinde sınıflandırılır. Bu tür atıklar bulaşıcı ajanlar, toksik kimyasallar ve ağır metaller ve radyoaktif maddeler içerebilir. Dolayısıyla tıbbi atıklar hem insan sağlığı hem de çevre sağlığı için tehlike oluşturmaktadır. Özellikle gelişmemiş ve gelişmekte olan ülkelerde tıbbı atık yönetiminin uygun mevzuat ve yöntemlerle sağlanması gereklidir.
The Public’s Response to the Health Communication Strategies to Prevent the Expansion of Covid 19 in Ethiopia, Focusing on Some Selected Zones of SNNPR
Authors: Tesfaye Alemayeu Degefa
Published: March 2023

Health communication is crucial for the creation of public awareness about the danger of a pandemic and safety measures. The study is situated in innovation diffusion and neutralization theories because these theories explain how new ideas spread in a society and how individuals normalize moral discomforts and avoid guilty feelings caused by a behavior against the acceptable norm in a society, respectively. Document and text analysis as well as in-depth interview were employed to collect the data. Documents were analyzed and health communication officers were interviewed. Thematic and textual analysis were employed for analysis. The analysis revealed that integrated media and inclusive and participatory communication were the communication strategies employed to alert the public about COVID 19. The public’s awareness about Coronavirus increased as a result of the communication. The public’s perception and scarcity of logistics were primary challenges. Moreover, the public became negligent in the prevention measures that should be taken due to their lifestyle, culture, and social influence as well as low economic status. As a result, they made themselves vulnerable to the risk of COVID 19. Since the public put themselves in risky situations, ardent and persuasive messages should be designed. Subsequently, the communication should consider changing beyond cognitive skills to bring behavior change. Keywords: COVID19, Coronavirus, Gamo Zone, Health Communication, Negligence, Ethiopia
THE PLACE OF WOMEN IN THE KINGDOM OF DAWRO, ETHIOPIA
Authors: Seid Ahmed
Published: March 2023

In many patriarchate societies of Africa, women were highly dominated in every aspect of life. Even in our contemporary world, there are few public figures that traversed the male domination. In spite of such dominance, women have had a better socio-political and economic status in some medieval kingdoms like Dawro, and the role and wisdom of prominent women in such kingdoms needs further investigation. The oral history of Dawro explicitly reveals that women had almost equal status with men. They had the right to choose their own counterpart as well as hold public office by competing with men except the office of king which was an absolute power vested on men. On the other hand, there was a unique office for women to act as the head of the king’s treasury. Similarly, in Dawro indigenous religion, every clan have their own male deities and Mariaminto is a ‘female’ deity for women. This kind of gender equity emanated from the unique Dawro socio-political system. It was introduced at the beginning of the 16th century by a famous King Adeto Erashu and it was further developed and reshaped by the active involvement and advice of the famous Dawro Queen Bale during the reign of her son, King Erashu Hallalla. In the Dawro indigenous political system, women had an equal chance to compete for political office, except the office of kingship. There was also a separate office, Tomosogenne (king’s treasury officer) for women who spun cotton, Shalwua, the local currency and currency of other neighboring kingdoms. Hence many spinners under the leadership of Tomosogenne spun more cotton in order to boost the economic powers of various Dawro kings. It is reported that there were many female public officials in the Dawro political system including Genne Bale, Genne Shoshote and many others who worked more for the glory of the kingdom, while few of them added fuel for the decline and fall of the state. According to Dawro elders, the most prominent one was Genne Angelate Gabe, a female Worrabba (regional ruler) in Tocha. Above all her other pursuits, she was credited with separating her region from Dawro and finally peacefully surrendering it to the invading force of King Menelik (18891913) in the second half of nineteenth century. Keywords: Indigenous administration, women, Dawro, Ethiopia
Tinjauan Duplikasi Nomor Rekam Medis Di Puskesmas Kelurahan Jatinegara Kaum Kecamatan Pulogadung
Authors: Nindia Safitri Elsa , Viatningsih Wiwik , Yulia Noor , Happy Putra Daniel
Published: March 2023

Berdasarkan Permenkes No. 269 Tahun 2008 dijelaskan bahwa rekam medis merupakan berkas yang terdiri dari catatan dan dokumen mengenai identitas pasien, pemeriksaan, pengobatan, tindakan dan pelayanan lain yang telah diberikan kepada pasien. Nomor rekam medis berperan penting dalam membedakan rekam medis pasien yang satu dengan lainnya dan memudahkan pencarian rekam medis, apabila pasien kemudian dateng kembali berobat disarana pelayanan kesehatan serta untuk kesinambungan informasi dan mencegah terjadinya nomor rekam medis. Duplikasi penomoran rekam medis adalah perulangan, keadaan rangkap atau nomor rekam medis ganda yang dimana satu nomor rekam medis memiliki beberapa pasien. Penelitian ini dilaksanakan untuk melihat adanya duplikasi dalam penomoran rekam medis. Metode penelitian menggunakan metode deskriptif dengan pendekatan analisa kuantitatif dan kualitatif, informan dalam penelitian ini adalah kepala rekam medis, Hasil penelitian dapat disimpulkan bahwa di bulan Desember Tahun 2021 terdapat duplikasi nomor rekam medis sebanyak 17 (1,4%) dikarenakan kurangnya petugas dan beberapa pasien lupa membawa Kartu Indeks Berobat (KIB) pada waktu kunjungan. Duplikasi terjadi karena oleh beberapa faktor 5M yaitu manusia (man) dikarenakan kurangnya petugas dan beberapa pasien lupa membawa Kartu Indeks Berobat (KIB) pada waktu kunjungan
Hubungan Posisi Meneran Terhadap Kejadian Robekan Perineum Pada Ibu Bersalin Di Puskesmas Rawat Inap Tepian Buah Kabupaten Berau
Authors: Hajrah Hajrah , Masyita Gita , Risnawati Risnawati , Prasetyarini Asih
Published: March 2023

Latar Belakang : Robekan perineum terjadi pada hampir semua persalinan pertama dan tidak jarang pada persalinan berikutnya. Hampir dari 90% pada proses persalinan banyak yang mengalami robekan perineum. Robekan perineum pada persalinan biasanya terjadi di garis tengah dan dapat meluas apabila kepala janin lahir terlalu cepat. Kejadian robekan perineum diseluruh dunia terjadi 2,7 juta ibu bersalin mengalami robekan jalan lahir, angka ini diperkirakan akan meningkat 6,3 juta pada tahun 2050. Di provinsi Kalimantan Timur sebanyak 375 orang (73,5%) mengalami kejadian robekan perineum pada ibu bersalin. Persalinan dan kelahiran merupakan kejadian fisiologis yang normal dalam kehidupan. Posisi meneran pada saat persalinan sangat mempengaruhi terjadinya robekan perineum. Ada beberapa pengaturan posisi pada ibu bersalin seperti posisi litotomi, dorsal recumbent, miring, dan setengah duduk. Dalam persalinan, posisi meneran ini yang sering digunakan Tujuan : untuk mengetahui hubungan posisi meneran terhadap kejadian robekan perineum pada persalinan dipuskesmas rawat inap Tepian Buah. Metode : rancangan desain yang digunakan dalam penelitian ini adalah deskriptif analitik dengan pendekatan Cross Sectional. Metode pengambilan sampel dengan menggunakan metode nonprobability sampling dengan teknik purpossive sampling. Besar sampel yang memenuhi kriteria inklusi dan eksklusi sebanyak 59. Hasil : Sebanyak 29 orang (49,2%) menggunakan posisi meneran litotomi dan didapatkan kejadian robekan sebanyak 31 kejadian (52,5%). Hasil uji statistik Fischer Exact yaitu nilai P Value (0,001) < ? (0,05). Kesimpulan: Posisi meneran litotomi paling banyak digunakan di puskesmas rawat inap Tepian Buah dengan kejadian robekan sebanyak 31 kejadian. Terdapat hubungan antara posisi meneran terhadap kejadian robekan perineum pada ibu bersalin di puskesmas rawat inap Tepian Buah kabupaten Berau.
PELATIHAN PEMBUATAN PIZZA RUMAHAN SEBAGAI MATERI PEMBELAJARAN PAUD TK GUGUS CAHAYA JINGGA BINTAN UTARA
Authors: Amalia Eva , Saputra Eryd , Nuryanto Heri
Published: March 2023

Program Pengabdian Masyarakat melalui kegiatan pelatihan pembuatan pizza  ini memberikan alternatif pembelajaran terhadap permasalahan yang dihadapi oleh pendidik yakni guru-guru PAUD  / TK Gugus Cahaya Jingga Kecamatan Bintan Utara, Kabupaten Bintan untuk melaksanakan kegiatan atau proses belajar mengajar kepada anak didik  secara interaktif dan  dapat lebih berkreasi dalam proses belajar dan mengajar secara atraktif .  Kegiatan Pengabdian kepada Masyarakat ini  bertujuan  agar dapat  memahami cara pembuatan pizza namun dengan kreasi rasa varian yang asli Indonesia dengan  bahan-bahan yang mudah diperoleh serta tidak mahal sehingga dapat menambah pengetahuan dan meningkatkan nilai jual serta dapat dijadikan bahan ajar kepada kelompok belajar sesama gugus di Kabupaten Bintan.   Metode pengabdian masyarakat meliputi  Sosialisasi Materi dan Referensi Pembelajaran disampaikan  dalam bentuk pemaparan dan tanya jawab kepada peserta dan pemaparan bahan melalui power point presentasi yang memuat referensi terkait  pengertian, asal usul, kreasi dan inovasi pizza   dan  peserta pelatihan kemudian dibekali pengetahuan tentang seluk beluk pizza dan proses pembuatannya secara demonstrasi yang nantinya kemudia dipraktekan di masing-masing kelompok. Berdasarkan evaluasi pelaksanaan dan hasil kegiatan dapat diidentifikasi faktor pendukung dan penghambat dalam melaksanakan program pengabdian pada masyarakat ini.   Pelatihan pembuatan pizza ini sangat membantu bagi pendidik yang ingin memberikan suatu variasi dalam pembelajaran praktek karena cukup mudah dilakukan.
SOSIALISASI PENDIDIKAN KEPARIWISATAAN KEPADA GURU-GURU PENDIDIKAN ANAK USIA DINI (PAUD) GUGUS JAHAYA JINGGA KAB. BINTAN
Authors: Supardi  , Haufi Sukmamedian  , Syailendra Reza Irwansyah Rezeki
Published: March 2023

The phenomenon of tourism has existed since the existence of human travel from one place to another and its development is in accordance with the socio-cultural community itself. Since then there have also been human needs that must be met during the journey, in addition to the motivation that drives humans to fulfill their needs. With the increase in human civilization, the urge to travel is getting stronger and the needs to be fulfilled are increasingly complex. The motivations and motives for traveling from time to time are of different levels, according to the development and socio-cultural, economic and environmental level of the community itself. The motivations and motives of people's journeys in prehistoric times are different from the motivations and motives of people's journeys in modern times. The way of travel and the facilities used by the community are still simple when compared to more advanced societies.
PEMANFAATAN SIPUT GONGGONG SEBAGAI BAHAN BAKU OLAHAN SOSIS SEBAGAI MAKANAN KHAS KOTA BATAM
Authors: Mulyadi Tirta , Suci Permata Sari
Published: March 2023

The gonggong snail is one of the marine biota whose distribution is abundant in Indonesia, especially Batam City. The utilization rate of gonggong snails in Batam City has not been maximized due to the lack of public knowledge to process gonggong snails into processed products that have higher economic value. This research was conducted to develop the use of gonggong snails as a new processed product in the food sector that can be used as a business opportunity. Researchers use gonggong snails as raw material for making sausages. This is done to increase the potential of gonggong snails and can become one of the typical foods of Batam City. This type of research is using a pre-experimental design with a one shot case study method. Using two comparison samples of gonggong snail meat and chicken meat as much as (100%: 0%) and (50%: 50%). Data collection techniques using hedonic quality test and hedonic test with research instruments using a questionnaire. The number of panelists as many as 20 people consisting of 5 trained panelists and 15 moderately trained panelists. The data obtained will be analyzed by the Mann Whitney test. The results of the Mann Whitney test showed that there was no significant difference in the taste, color and texture of the gonggong snail sausage, while in scent there was a significant difference. The results of the hedonic test showed that the panelists preferred the taste and scent of the gonggong snail sausage with formulation B (50%:50%), the color that the panelists preferred was the gonggong snail sausage with formulation A (100%:0%), while for the texture of the sausage The panelists Gonggong snails liked both formulations A (100%:0%) and B (50%:50%).
STRATEGI PENGEMBANGAN DESA WISATA EKOLOGIS DI DESA JEMPANANG DI PETANG KABUPATEN BADUNG BALI
Authors: Kiskenda Dewa , Nyoman Agus trimandala
Published: March 2023

Ecotourism Jempanang D'alas is trying to encourage the number of tourist visits. However, tourist visits are still considered not optimal. This study discusses existing conditions and examines strengths and weaknesses as well as opportunities and threats to formulate strategies and programs for the development of Jempanang D'alas Ecotourism in Belok Sidan Village optimally and maintain its sustainability. This study uses a quantitative and qualitative approach. Data collection was carried out by observation, in-depth interviews with (1) Belok Sidan Village Head, Petang Subdistrict (2) Jempanang D'alas ecotourism manager (3) local traditional leaders. Then an analysis was carried out using the SWOT method. Based on the SWOT analysis, alternative strategies that can be applied to the development of Ecotourism in Japan D'alas were obtained, namely (1) strategies for creating quality ecotourism products, (2) strategies for increasing promotion through the application of information technology, (3) strategies for developing human resource competencies and ( 4) marketing strategy for ecotourism products for tourists who stay in villas and tourist attractions in Belok Sidan Village and its surroundings.
Smart Walk: A Smart Stick for the Visually Impaired
Authors: Luthuli Musawenkosi Blessing , Malele Vusumuzi , Owolawi Pius Adewale
Published: March 2023

It is estimated that globally, 285 million people in the world are visually impaired, while 39 million are completely blind. Visual impairment may cause difficulties for people to do their daily activities. There is a need for innovative, ambient, or active assisted living (IAAL) solution(s) to be designed, developed, and deployed for the visually impaired individuals. This paper presents a design of a smart stick for visually impaired individuals as an IAAL solution. The smart stick comprises ultrasonic sensors to detect objects and obstacles, a camera to capture the objects, a GPS module for location update and navigation, and a Raspberry Pi 3B+ which acts as a central unit for the whole system. The smart stick was tested in different environments and backgrounds. The image classification and object detection accuracy of the smart stick system was within the range of 59 per cent to 89 per cent (minimum and maximum range). The smart stick helped the visually impaired individuals to manage walking around their environment. The proposed system will improve the life of visually impaired people since it managed to accurately identify and detect objects with a 89 per cent accuracy level at a one meter distance.
Sinema Eserlerinde Tasarım Kimlik İlişkisi: Yüzüklerin Efendisi Örneği
Authors: Ardatürk Ahmet Şadi
Published: March 2023

Bilme eylemi noktasında belki de en çok kullanılan duyunun görme duyusu olduğu ifade edilebilir. Görsel olanla kurulan ilgi bu bilme eylemini içermektedir. Görsel olan ister bir gösterge, temsil ister bir sanat yapıtı olsun bireyle, izleyiciyle direkt bağlamlar oluşturur.

Görsel bir sanat olan sinema içerisinde; mekân, karakter, kurgu, kıyafet, nesne vb. farklı tasarım noktaları barındıran bir organizasyon bütünlüğü sunar. Bu noktada tasarım öğeleri sinema eserinin gerçekliği oluşturan parametrelerine dönüşür.

Bu çalışma tam olarak bu parametrelerden bir tanesi olan nesneyle kimlik ilişkisine odaklanmaktadır. Sinema eseri içerisinde kullanılan tasarlanmış nesnelerin salt olarak bir nesne olmaktan ötesini barındırdıkları fikri bu çalışmayı imkânlı kılmıştır. Eser sahibinin söylemek istediği bazı söylemlerin nesneler üzerinden anlamlandığı anlar tartışmanın konusunu oluşturmaktadır. Bu söylemler gösterge bilimsel analizle irdelenmiştir.

Bu bağlamda ilgili düşüncenin araştırılması için John Ronald Reuel Tolkien’in Yüzüklerin Efendisi serisi çalışmanın temel araştırma alanını oluşturmakta, bu alan içerisinde özellikle kimlik ve karakterle ilişki kuran aynı zamanda beden ve kurguyla uzamlar oluşturan öğeler olarak savaş enstrümanları temel nesneler olarak ele alınmıştır.

Çalışmanın strüktürü; ilgili enstrümanların fonksiyonel, ergonomik, estetik vb. gibi tasarımsal ve sanatsal özelliklerinin kimlik ve karakterle bağdaştırılması aynı zamanda eser içerisindeki söylemlerinin keşfedilmesiyle oluşmaktadır. Sinema ve tasarım ara kesitinde var olan çalışma üretimle temsili, nesneyle kimliği, formla karakteri, olguyla hikâyeyi vb. buluşturan noktalara temas etmektedir. Sonuçta ilgili yapıtlarda var olan tasarlanmış nesnelerin birer kimlik anlatı aracı olduğu, hikâyede var olan bazı kaideleri doldurduğu ortaya konulmuş, sinema ve sinematografik anlatım içerisinde tasarım nesnesinin yeri ve pozisyonu keşfedilmeye çalışılmış, ürün-kimlik bağlamları oluşturulmuştur.
Genetic Diversity Analysis of Avena sterilis L. Germplasm by Microsatellite Markers
Authors: KAYA ALTOP Emine
Published: March 2023

Avena sterilis is an important grassy weed that causes a problem in wheat cultivation areas, and intensive herbicides are used to control it. Genetic diversity study is important to have information how on the effect weed species of the environmental factors and herbicides. The high level of genetic diversity within the species is a guarantee for adaptation to changing environmental conditions. This study was conducted based on complaints of the loss of effectiveness during the chemical control. Analyses were carried out on 27 selected populations collected from wheat cultivation areas in Turkey's Middle Black Sea region. Seventy-seven alleles from microsatellite loci were detected, and the average number of alleles per locus was determined as five using 17 microsatellite primers. The average gene diversity (GD) and polymorphism information content (PIC) values were 0.894 and 0.732, respectively. According to the UPGMA dendrogram generated using Average Linkage, the populations were clustered into two main groups. A high degree of diversity was found among the studied steril oat genotypes, and it is seen that there is no geographical isolation. It is understood that this situation primarily provides adaptation to those geographical areas by transporting weed seeds from other provinces in various ways. According to these findings, issues such as crop rotation, cultural control methods, encouraging the use of certified seeds, and the use of herbicides with different mechanisms of action can be listed among the measures that can be taken to control the high genetic diversity, which is an indicator of herbicide resistance.
Making Union Membership the Default Option in Canada: Would It Be Supported and Effective?
Authors: Harcourt Mark , Gall Gregor , Wilson Margaret
Published: March 2023

Income inequality has risen in Canada with the decline in union density and, thus, in union influence. Both trends have occasioned various proposals to reform federal and provincial labour relations systems, especially those aspects concerning certification. However, most proposals have been based on minor modifications to the Wagner Model of exclusive, majoritarian representation. To realize the full potential of these reform proposals, including, importantly, the likes of ‘broad-based bargaining,’ we contend that union membership should be the default option for new workers. Such a change would enable these proposals to increase absolute and relative levels of union membership, thereby providing the organizing resources (financial, human) required for much higher levels of union influence. In this study, we show that those living in Canada generally support union membership by default and would not opt out afterwards. We believe this popular support justifies making union membership automatic for new workers.

Abstract

Union density has declined in Canada and, with it, wage inequality has risen, occasioning various proposals to reform the certification systems operating provincially and federally. However, such proposals are ordinarily based on only minor changes to the Wagner Model. We contend that to realize the full potential of these proposals, union membership by default is required to increase union membership levels. In this study, we show that those living in Canada generally support union membership as the default option and would not opt out afterwards. We believe this popular support justifies more comprehensive study of the proposal to make union membership automatic for new workers.
Territoire, frontières et mixité sociale : le cas de la Fonderie
Authors: Many Holly Figaro , Leone Virginie
Published: March 2023

Le quartier Fonderie de Mulhouse a la particularité d’être un « quartier prioritaire de la politique de la ville » (QPV) accueillant une faculté. Cependant, il ne déroge pas à la règle du cloisonnement entre les différentes populations le fréquentant. La mise en oeuvre de dispositifs de soutien scolaire et des cours de FLI (français langue d’intégration), au sein même de cette faculté, a changé les représentations, tant chez les habitants du quartier que chez les étudiants et le personnel universitaire. Cette étude à valeur heuristique propose de comprendre les mécanismes et les enjeux liés à la territorialité, les frontières et la mixité sociale à travers des actions socioéducatives sur le quartier Fonderie.
Advancing Radical Food Geographies Praxis through Participatory Film
Authors: Levkoe Charles Z. , Lowitt Kristen , Furlotte Sarah , Sayers Dean
Published: March 2023

The academic field of geography is deeply embedded within capitalist and settler colonial logics and has played a major role in suppressing and concealing Indigenous histories along with rights claims, cultures, and practices. While geography’s origins are deeply problematic, over the past decades, many scholars and practitioners have offered counter theoretical and practical perspectives and approaches. Radical food geographies praxis is one such example that is rooted in engaged and socially relevant theory, practice, and reflection. In this article, we present reflections from our experience with radical food geographies research praxis through a collaborative food sovereignty, action-oriented project co-developed and co-led by two settler academics, a documentary filmmaker, and the Chief of Batchewana First Nation. From 2018-2022, we embarked on an effort to share stories of Batchewana First Nation’s historical and current fishing practices, culture, and governance through the co-creation of a feature length documentary film titled, Lake Superior Our Helper: Stories from Batchewanaung Anishinabek Fisheries (https://www.batchewanaungfish.ca). To write this paper, we engaged in a process of collective autoethnography that involved documenting our individual reflections on the project and then bringing these perspectives into dialogue. Emerging from this process, we share our insights for an engaged research praxis, focusing on meaningful and authentic relationships and partnership building, participatory film as a tool for collaborative research, and radical food geographies. We present these insights with the aim of improving our own individual and collaborative practice and to share our learnings with other scholars, activists, and community practitioners engaged in similar partnership-based and praxis-oriented geographic research.
Internationalization Policies and Strategies in Ireland and Brazil: a comparative study
Authors: Ramos Rosane Karl
Published: March 2023

This study presents and compares the internationalization in education process in Ireland and Brazil in terms of macro-level (policies), and micro-level (strategies and practices). The main research questions are: (a) how is the internationalization process presented in official/government publications? (b) what are the main strategies used towards its implementation? This is a qualitative study based on non-comprehensive scoping review on documents, such as policies, recommendations and guidelines, and at the strategic level (micro level), reports, journal articles and student guides. The analysis was oriented by two perspectives:  hegemonic and counter-hegemonic (Abba & Corsetti, 2016). Amongst the findings, it can be inferred that both countries follow the hegemonic perspective, with significant emphasis on the economic implications and benefits of internationalization.
“Por que o seu ‘caderninho’ está cheio de escritas?”
Authors: Silva Anna Líssia da , Haddad Lenira
Published: March 2023

Este artigo está inserido no contexto de uma tese de doutorado, cujo objetivo foi mapear a produção de pesquisas com crianças acerca de seus dizeres sobre questões relacionadas ao campo das diferenças. Na tese foram mapeados 323 os trabalhos dentro do campo das diferenças realizados em contextos de Educação Infantil. Dentre eles, foram selecionados 14 trabalhos que se denominaram pesquisas com crianças. Neste artigo, são analisadas as discursividades das pesquisadoras sobre pesquisas com crianças, metodologias e questões éticas que envolvem a participação das crianças. Também são destacadas as múltiplas formas e gestos de estar presente nas pesquisas que as crianças empreenderam em um movimento de ativo e criativo. A contribuição das produções analisadas indica que as pesquisas que abrem espaço para uma participação ativa das crianças, com a construção de espaços mais democráticos e sensíveis às vozes infantis, produzem saberes que possibilitam repensar os modos de produzir conhecimento sobre a vida das crianças e suas formas de ser e estar no mundo.

Palavras-chave: Pesquisa com crianças. Participação infantil. Crianças pequenas.
Uma proposta de protocolo para intervenções breves em psicologia clínica
Authors: Freire Klessyo do Espirito Santo , Ribeiro Cortez Cardozo Barata de Almeida Hessel Betriz
Published: March 2023

Este estudo teve como objetivo apresentar a construção um protocolo voltado à intervenções breves no campo da psicologia clínica, visto a ausência do desenvolvimento até o momento de protocolos e/ou modelos de formulação de caso clínico nesta modalidade de atendimento. Apesar disso, as evidência em psicologia clínica apontam que o processo de atendimento psicólogico necessita ser responsivo e deve se adaptar às necessidades e demandas do paciente, necessitando de uma formulação de caso clínico. Para tanto, apresentou um protocolo de intervenções breves para psicoterapia breve, aconselhamento psicológico e plantão psicológico. Para a construção do protocolo, obteve-se como base a atuação de um projeto de extensão voltado a atendimentos breves, realizado em uma universidade pública federal em Salvador desde 2020. A construção do instrumento beaseou-se paradigmas contemporâneos em psicologia clínica, o modelo dos fatores comuns e a psicoterapia baseada em processos. A partir disso, foram construídos 11 itens a serem preenchidos pelo psicólogo no começo do atendimento psicológico. Entretanto, entende-se que o protocolo não deve ser aplicado como um modelo rígido, mas sim deve ser ajustado de acordo com as especificidades de cada paciente, preservando a estrutura singular de cada processo de atendimento psicológico. Como limitações, foi delimitada a ausência de realização de pesquisas empíricas que busquem avaliar a eficácia desse protocolo, o que é recomendado para investigações futuras.
Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects
Authors: Chen Holly Y , Swaroop Manju , Papal Samantha , Mondal Anupam K , Song Hyun Beom , Campello Laura , Tawa Gregory J , Regent Florian , Shimada Hiroko , Nagashima Kunio , de Val Natalia , Jacobson Samuel G , Zheng Wei , Swaroop Anand
Published: March 2023

Ciliopathies manifest from sensory abnormalities to syndromic disorders with multi-organ pathologies, with retinal degeneration a highly penetrant phenotype. Photoreceptor cell death is a major cause of incurable blindness in retinal ciliopathies. To identify drug candidates to maintain photoreceptor survival, we performed an unbiased, high-throughput screening of over 6000 bioactive small molecules using retinal organoids differentiated from induced pluripotent stem cells (iPSC) of rd16 mouse, which is a model of Leber congenital amaurosis (LCA) type 10 caused by mutations in the cilia-centrosomal gene CEP290. We identified five non-toxic positive hits, including the lead molecule reserpine, which maintained photoreceptor development and survival in rd16 organoids. Reserpine also improved photoreceptors in retinal organoids derived from induced pluripotent stem cells of LCA10 patients and in rd16 mouse retina in vivo. Reserpine-treated patient organoids revealed modulation of signaling pathways related to cell survival/death, metabolism, and proteostasis. Further investigation uncovered dysregulation of autophagy associated with compromised primary cilium biogenesis in patient organoids and rd16 mouse retina. Reserpine partially restored the balance between autophagy and the ubiquitin-proteasome system at least in part by increasing the cargo adaptor p62, resulting in improved primary cilium assembly. Our study identifies effective drug candidates in preclinical studies of CEP290 retinal ciliopathies through cross-species drug discovery using iPSC-derived organoids, highlights the impact of proteostasis in the pathogenesis of ciliopathies, and provides new insights for treatments of retinal neurodegeneration.
Functional and pharmacological analyses of visual habituation learning in larval zebrafish
Authors: Lamiré Laurie Anne , Haesemeyer Martin , Engert Florian , Granato Michael , Randlett Owen
Published: March 2023

Habituation allows animals to learn to ignore persistent but inconsequential stimuli. Despite being the most basic form of learning, a consensus model on the underlying mechanisms has yet to emerge. To probe relevant mechanisms, we took advantage of a visual habituation paradigm in larval zebrafish, where larvae reduce their reactions to abrupt global dimming (a dark flash). We used Ca2+ imaging during repeated dark flashes and identified 12 functional classes of neurons that differ based on their rate of adaptation, stimulus response shape, and anatomical location. While most classes of neurons depressed their responses to repeated stimuli, we identified populations that did not adapt or that potentiated their response. These neurons were distributed across brain areas, consistent with a distributed learning process. Using a small-molecule screening approach, we confirmed that habituation manifests from multiple distinct molecular mechanisms, and we have implicated molecular pathways in habituation, including melatonin, oestrogen, and GABA signalling. However, by combining anatomical analyses and pharmacological manipulations with Ca2+ imaging, we failed to identify a simple relationship between pharmacology, altered activity patterns, and habituation behaviour. Collectively, our work indicates that habituation occurs via a complex and distributed plasticity processes that cannot be captured by a simple model. Therefore, untangling the mechanisms of habituation will likely require dedicated approaches aimed at sub-component mechanisms underlying this multidimensional learning process.
Biographical Introduction and Summary of Contents
Authors: Aspaas Per Pippin
Published: March 2023

The fifteenth volume in the series presents a monograph by the famous meteorologist and astronomer Anders (in Latin: Andreas) Celsius (1701–1744), founder of the Centigrade temperature scale known as °C. From a young age, Celsius collected observations of the aurora borealis from Swedish territories. He participated in the editing of the Acta Literaria Sveciæ, the journal of the Royal Swedish Society of Learning and Sciences in Uppsala, in which a substantial number of observations were published. The journal articles in question were often quite short, with the aurora often inserted in lists of meteorological observations with little space for descriptions. By contrast, Celsius’ monograph contains a ten pages long historical intro­duction discussing the periodicity of the phenomenon, arguing that one should differentiate between minor and major aurorae: only the latter were visible on the European Continent and British Isles. There follows a 48-page chronological account of 316 observations made in Sweden, including Finland, during the period from 1716 to 1732. A network of observers established by the Uppsala society provided the basis for this impressive display of Swedish science. Celsius himself had made 67 of the 316 observations; the rest had been reported by sixteen other amateur and professional practitioners of science. The introduction, written by neo-Latinist and historian of science Per Pippin Aspaas, contains biographical information on each of the various observers as well as extracts of Celsius’ text in English translation.
Dataset construction method of cross-lingual summarization based on filtering and text augmentation
Authors: Pan Hangyu , Xi Yaoyi , Wang Ling , Nan Yu , Su Zhizhong , Cao Rong
Published: March 2023

Existing cross-lingual summarization (CLS) datasets consist of inconsistent sample quality and low scale. To address these problems, we propose a method that jointly supervises quality and scale to build CLS datasets. In terms of quality supervision, the method adopts a multi-strategy filtering algorithm to remove low-quality samples of monolingual summarization (MS) from the perspectives of character and semantics, thereby improving the quality of the MS dataset. In terms of scale supervision, the method adopts a text augmentation algorithm based on the pretrained model to increase the size of CLS datasets with quality assurance. This method was used to build an English-Chinese CLS dataset and evaluate it with a reasonable data quality evaluation framework. The evaluation results show that the dataset is of good quality and large size. These outcomes show that the proposed method may comprehensively improve quality and scale, thereby resulting in a high-quality and large-scale CLS dataset at a lower cost.
Automatic design and optimization of educational space for autistic children based on deep neural network and affordance theory
Authors: Chu Linya , Li Wen
Published: March 2023

In recent years, the incidence of autistic children has shown rapid growth worldwide. The rapid development of education and rehabilitation institutions for autistic children is of great significance to the rehabilitation of this group. However, the research on indoor space environments and functional facilities for autistic children in China is still in its infancy. Reasonably and effectively, zoning the education and rehabilitation space for autistic children can promote better communication and learning between autistic children and rehabilitation therapists and effectively promote the rehabilitation progress of autistic children. However, the existing education and rehabilitation space for autistic children has some problems, such as unscientific indoor partition, indoor space layouts mainly relying on manual work, heavy workload and low efficiency. Therefore, it is of great research value and practical significance to explore the intuitive design and optimization of the education and rehabilitation space layout for autistic children. This study first evaluates and optimizes the educational space for autistic children based on the affordability theory. Then, this study proposes a layout recommendation algorithm based on deep learning, which is used to improve the layout efficiency of the education and rehabilitation space for autistic children and realize real-time online layout. The scene information is digitized in binary code. The segmentation and layout network models are constructed through bidirectional long short-term memory (LSTM) to discover the long segment pre-segmentation of house type and obtain the layout results. The word embedding algorithm is used to abstract the cross features between each vector segment, and the dimension of the feature matrix is reduced to improve the speed and accuracy of the layout scheme recommendation. The experimental results show that our method can learn the design rules from the data set and has achieved better results than the existing methods. This study provides an adequate theoretical basis and design reference for the research of residential education space for autistic children.
Day and night camera trap videos are effective for identifying individual wild Asian elephants
Authors: Montero-De La Torre Sasha , Jacobson Sarah L. , Chodorow Martin , Yindee Marnoch , Plotnik Joshua M.
Published: March 2023

Regular monitoring of wild animal populations through the collection of behavioral and demographic data is critical for the conservation of endangered species. Identifying individual Asian elephants (Elephas maximus), for example, can contribute to our understanding of their social dynamics and foraging behavior, as well as to human-elephant conflict mitigation strategies that account for the behavior of specific individuals involved in the conflict. Wild elephants can be distinguished using a variety of different morphological traits—e.g., variations in ear and tail morphology, body scars and tumors, and tusk presence, shape, and length—with previous studies identifying elephants via direct observation or photographs taken from vehicles. When elephants live in dense forests like in Thailand, remote sensing photography can be a productive approach to capturing anatomical and behavioral information about local elephant populations. While camera trapping has been used previously to identify elephants, here we present a detailed methodology for systematic, experimenter differentiation of individual elephants using data captured from remote sensing video camera traps. In this study, we used day and night video footage collected remotely in the Salakpra Wildlife Sanctuary in Thailand and identified 24 morphological characteristics that can be used to recognize individual elephants. A total of 34 camera traps were installed within the sanctuary as well as crop fields along its periphery, and 107 Asian elephants were identified: 72 adults, 11 sub-adults, 20 juveniles, and four infants. We predicted that camera traps would provide enough information such that classified morphological traits would aid in reliably identifying the adult individuals with a low probability of misidentification. The results indicated that there were low probabilities of misidentification between adult elephants in the population using camera traps, similar to probabilities obtained by other researchers using handheld cameras. This study suggests that the use of day and night video camera trapping can be an important tool for the long-term monitoring of wild Asian elephant behavior, especially in habitats where direct observations may be difficult.