bluuebunny/crossref_metadata_2025 huggingface dataset:
Universidade e commodity: quando o mercado coloniza a educação superior
Authors: Trevisol Marcio Giusti , Fávero Altair , Mikolaiczik Daniê Regina
Published: February 2025

O estudo abordou a relação entre a expansão da educação superior no Brasil e a atuação do mercado educacional influenciado pela racionalidade neoliberal. O objetivo é apresentar uma análise subsidiada por um aporte teórico que permita explicar as contradições do avanço do mercado na educação superior, seus desafios e impasses a partir dessa racionalidade. Trata-se de um estudo de abordagem qualitativa, objetivo exploratório, com procedimento bibliográfico e documental, ancorado no método analítico-hermenêutico. Os resultados apontam que os ditames do mercado têm levado à precarização do ensino, da pesquisa e da extensão na educação superior. A universidade tornou-se uma mercadoria incorporada à racionalidade neoliberal baseada na maximização do lucro, da concorrência e da competitividade, o que compromete sua missão histórica em promover o conhecimento. Os dados indicam a urgência de repensar políticas de educação superior no Brasil, a fim de coibir a expansão de um ensino apenas com fim mercantil.
NADPH Oxidase: A Potential Therapeutic Target to Reduce Primary Sclerosis Cholangitis Following Liver Transplantation
Authors: Aliakbarian Mohsen , Ashrafzadeh Kiarash , Ferns Gordon A , Hadian Reyhaneh , Khodashahi Rozita , Arjmand Mohammad-Hassan
Published: February 2025

The molecular mechanisms and causes of primary sclerosis cholangitis (PSC)
post-liver transplantation are still unclear. PSC is a progressive cholestatic hepatobiliary
disease that happens in about 25% of patients post-liver transplantation and requires re--
transplantation. Nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase
or Nox) is a family of transmembrane proteins whose main function is producing reactive
oxygen species (ROS). ROS generation as a result of NADPH oxidase activity of
Kupffer cells and polymorphonuclear leukocytes has been implicated in the pathogenesis
of ischemia-reperfusion injuries after liver transplantation, and is related to intraand/
or extrahepatic non-anastomotic biliary stenosis or PSC. In addition, Nox-derived
ROS upregulates several molecular pathways to induce hepatocyte apoptosis and hepatic
stellate cell (HSC) activation to promote hepatobiliary fibrogenesis. Understanding
the multiple molecular aspects of Nox in the development of PSC post-transplantation
may help identify new drugs to prevent this disorder.
Advances in Targeting Neutrophil Extracellular Traps as a Promising
Approach for Breast Cancer Treatment
Authors: Mi Jiale , Guo Jiani , Kang Kang , Wang Shiqi , Huang Mingde
Published: February 2025

Neutrophils release neutrophil extracellular traps (NETs), a reticular structure mainly
composed of antimicrobial peptides, DNA, and histones. Neutrophil elastase (NE), matrix metalloproteinase-
9, and histone G are the key components of NETs critically involved in breast cancer
invasion and migration, which suggests an important role of NETs in tumorigenesis and metastasis.
Studies have reported that NETs significantly promote breast cancer invasion, intravascular
infiltration, and distant metastasis by inducing epithelial-mesenchymal transition (EMT),
remodeling the extracellular matrix, and modulating the immune microenvironment. Meanwhile,
NETs also function crucially in capturing circulating tumor cells, forming a pre-metastatic microenvironment,
and awakening dormant cancer cells. Notably, NETs are also closely associated
with chemotherapy and immunotherapy resistance in breast cancer. Therapeutic strategies targeting
NETs, including DNase I, PAD4 inhibitors, elastase inhibitors, and histone C inhibitors,
have been widely studied. These targeted therapies can effectively suppress the generation of
NETs, improve drug efficacy, and delay tumor metastasis. This review aimed to systematically
elucidate the mechanism of action of NETs in the progression and drug resistance of breast cancer
and explore potential targeted therapeutic strategies against NETs. These strategies could effectively
inhibit the generation of NETs, delay the progression of breast cancer, and improve
therapeutic efficacy. An in-depth study of the mechanism of action of NETs and the clinical significance
of their targeted interventions is expected to provide a new direction for breast cancer
treatment.
Biochanin-A: A Potential Candidate for the Treatment of Alzheimer’s Disease
Authors: Singh Niraj Kumar , Bhushan Bharat
Published: February 2025

Alzheimer's disease (AD), the most common form of dementia, is a multifactorial
neurological condition characterized by progressive loss of memory and learning, uncontrollable
movement, difficulty processing visual images, and impairment of reasoning and/or judgment
skills. Although the exact cause of AD is still unknown, recent evidence suggests that environmental,
lifestyle, and genetic factors are common contributors to the disease's progression. Pathophysiological
features of AD include amyloid beta (Aβ) accumulation, abnormal deposition of
neuritic plaques and neurofibrile tangles, cholinergic dysfunction, neuroinflammation, and oxidative
stress burden along with mitochondrial dysfunction. There are currently no pharmaceutical
methods or medications that can stop the progression of a disease. More attention is now
being paid to natural products, herbal medicines, and different bioactive phytoconstituents, particularly
flavonoids, as alternative therapies and useful resources for finding new drug candidates
for the treatment of AD-like symptoms. A dietary isoflavone, biochanin-A, which is isolated
from the leaves and stems of Trifolium pretense L. (family: Leguminosae), possesses remarkable
anti-inflammatory and antioxidant properties along with cognitive-enhancing effects.
Biochanin-A exhibits notable neuroprotective effects by reducing Aβ deposition, decreasing
apoptosis, and preventing the production of pro-inflammatory mediators, including TNF-α, IL-
1β, and NO. Various preclinical reports explore the pharmacological role of biochanin-A against
experimentally-induced AD and highlight that it can alter numerous signaling pathways, including
Nrf2, NF-κB, JNK, MAPK, and Bcl-2/Bax. The present review article summarizes the numerous
research studies that have evaluated the role of biochanin-A for dementia associated
with AD. As part of a comprehensive program, biochanin-A has very exceptional potential to
prevent and treat AD-related cognitive impairment. It is envisaged that these potential chemical
moieties can be employed in the drug discovery process to identify efficacious and safe therapy
for the treatments for AD-like manifestation.
Advances and Challenges in Traumatic Brain Injury from a Forensic Perspective
Authors: Zhao Shu-Quan , Shi Yan-Wei , Wang Xiao-Guang , Liu Ke , Zhao Hu
Published: February 2025

Traumatic brain injury (TBI) is one of the leading causes of death and disability. Animal
and clinical studies of TBI have greatly changed the clinical practice of TBI with the development
and application of new technologies. However, with the development of forensic science, legal issues
related to TBI continue to emerge, and it is still far from satisfactory that the practical application of
relevant research findings as legal evidence in court practice. This review discusses an overview of
the latest progress of TBI through neuropathological changes, secondary injury mechanisms, postmortem
neuroimaging, cognitive, emotional, and behavioral impairments, biomarkers, and the effects
of toxins and drugs on brain injury from a forensic perspective. Meanwhile, we highlight the
interpretability and limitations of findings on TBI in legal proceedings are ongoing challenges.
Cytokine Gene Variants as Risk Predictors and Prognostic Biomarkers for Cervix Cancer: A Revisit
Authors: Kushwah Atar Singh , Gupta Maneesh Kumar , Srivastava Kirti , Banerjee Monisha
Published: February 2025

Cervix cancer is the most frequent cancer among women worldwide. Chronic HPV infections
can lead to the induction of immune tolerance, where the immune system becomes less responsive
to the virus over time. This can allow the virus to persist and establish a long-term infection. Initially,
HPV modulates various components of the innate immune system, including interferon signaling
pathways. By interfering with innate immune responses, HPV can further dampen the host's ability
to mount an effective antiviral immune response. The genetic alterations in these cytokines contribute
to altered cytokine production, which may influence the severity of infection and cancer development.
Platinum-based chemo-radiotherapy is the only first-line treatment available for cervix
cancer. Chemoradioresistance with variable toxicity is the major challenge in clinical practices. Individual
genetic makeup determines their disease development and variable treatment response. Hence,
interindividual-based genetic biomarkers need to develop to better cancer prognosis. Biomarkers can
predict the risk of disease and help to take precautionary measures and delay the onset of the disease.
Previous studies reported that genetically altered IL-1RN, IL-1b, IL-6, and TNF-α associated with
cervix oncogenesis, and these could be a potential prognostic marker of cervix cancer.
Integrative Analysis of the Impact of Prenatal Depression on the Newborn Intestinal Microbiota
Authors: Taha Wafaa , Anachad Oumaima , Taouil Amine , Saadoune Chaimaa , Messal Mariame El , Bennis Faiza , Chegdani Fatima
Published: February 2025

Background:

More than 15% of women develop symptoms of depression during pregnancy,
which often affects the mental and physical development of the newborn by altering its intestinal
microbiota. Previous studies revealed that the gut microbiota plays a crucial role in the
maturation of systems involved in the gut-brain axis, including the gastrointestinal system, the immune
system, and the hypothalamic-pituitary-adrenal system axis.

Methods:

This study aims to explore the cross-talk between the prenatal depression process and
neonatal intestinal microbiota diversity. A total of 100 differentially expressed genes (DEGs) associated
with prenatal depression were collected from various scientific publications and databases.
Bioinformatics tools were used to analyze these DEGs. The STRING database. ToppGene database
and DICE were employed for this integrative analysis.

Results:

The network generated by the STRING database identified six pivotal genes: TNF, BDNF,
IL-6, NR3C1, IGF2, and POMC. These genes regulate response to endogenous hormones, particularly
cortisol secretion in newborns, as well as inhibiting serotonin secretion. Moreover, these
genes are linked to major depressive disorder and other mental diseases, contributing to maternal
and neonatal gut microbiota dysbiosis. Analysis using ToppGene and DICE’s further validated the
biological processes identified by String, including the regulation of cellular cortisol secretion,
metabolic processes, and serotonin inhibition.

Conclusion:

The bioinformatics tools employed in this study allowed us to identify pivotal genes
involved in prenatal depression, their associated signaling pathways, and their roles in modulating
maternal and neonatal gut microbiota.
Evaluating the Effectiveness of Laser Peripheral Iridotomy on Angle-closure Diseases: The Role of Spectral Domain Anterior Segment Optical Coherence Tomography (SD AS-OCT) in Indonesia Tertiary Eye Hospital
Authors: Rifada Maula , Ramdhani Rizki Fasa , Nadifa Iffa , Gustianty Elsa , Umbara Sonie , Prahasta Andika , Irfani Irawati , Knoch Andrew M. H. , Virgana Rova
Published: February 2025

Background

Laser Peripheral Iridotomy (LPI) is a management approach in primary angle-closure disease by eliminating the presence of a pupillary block. Spectral Domain Anterior Segment Optical Coherence Tomography (SD AS-OCT) can measure the anterior chamber parameters quantitatively.

Objective

To determine the difference in anterior biometric parameters before and after LPI using SD AS-OCT in primary angle closure disease.

Methods

This is an analytical observational study with a cross-sectional method. A total of 22 eyes were included and underwent LPI. The angle opening distance (AOD 500 and 750), trabecular iris space area (TISA 500 and 750), anterior chamber depth (ACD), anterior chamber width (ACW), anterior chamber area (ACA), and lens vault (LV) was measured using SD AS-OCT before and 1 week after LPI. Statistical tests were performed with paired t-test or Wilcoxon's alternative test.

Results

We conducted LPI in 22 eyes with primary angle closure disease (9 eyes Primary Angle Closure Suspect (PACS), 7 eyes Primary Angle Closure (PAC), and 6 eyes Primary Angle-Closure Glaucoma (PACG)). There was a significant decrease of intraocular pressure (p=0.001) and a significant increase of mean values for AOD500, AOD750, TISA500, and TISA750 (p=0.0001) before and 1-week after LPI. The anterior segment showed statistically significant change in ACD, ACW, and ACA before and after LPI (p=0.006, p=0.001, p=0.049; respectively). The changes of LV did not show any statistically significant difference (p=0.770).

Conclusion

There was a significant difference in anterior biometric parameters in angle closure disease. Laser Peripheral Iridotomy could widen the anterior chamber and the angle.
Leveraging Magnetic Nanoparticles for modern Oncology: Revolutionary Approaches to Colorectal Cancer Treatment and Future Advancements
Authors: Patil Chethan , Naik Prasiddhi , T Mallamma , Goudanavar Prakash
Published: February 2025

Magnetic nanoparticles (MNPs) represent a transformative advancement in the fight
against cancer. They offer an innovative method for diagnosing the condition, managing its symptoms,
and monitoring its progression in real-time. This paper explores the extraordinary potential of
MNPs to revolutionize cancer therapy through advanced imaging methods, magnetic hyperthermia,
and targeted drug delivery. Medical experts can now accurately target tumors using MNPs while
inflicting minimum damage to healthy cells. The future innovation of personalized magnetotheranostic
will involve MNPs by integrating real-time diagnostics with tailored treatment regimens
based on the molecular profile of each patient's malignancy. MNPs will transform cancer immunotherapy
through liquid biopsies for early cancer detection, gene therapy for resistant tumors, and
immune modulation. Drug resistance and tumor recurrence represent significant challenges in oncology;
nevertheless, MNPs, with breakthroughs such as biodegradable nanoparticle designs and enhancements
facilitated by artificial intelligence, provide considerable promise for addressing these
issues. Safer, more effective, and personalized cancer treatments are attainable, and this review illustrates
the unequivocal potential of MNPs as a versatile, patient-centric strategy. In the future, MNPs
may offer promise to cancer patients globally by enhancing survival rates and transforming cancer
treatment to be more precise, minimally invasive, and adaptable.
Sustainability in Smart Cities: A 5G Green Network Approach
Authors: Pradhan Devasis , Sahu Prasanna Kumar , Bruno Alessandro
Published: February 2025

The rapid urbanization and technological advancements of the 21st century
have propelled the evolution of smart cities, aiming to enhance efficiency, connectivity,
and overall quality of life. As cities strive to address environmental challenges, this
research investigates the integration of a 5G Green Network as a pivotal component of
smart city sustainability. The study explores the intersection of 5G technology and
environmentally conscious practices, aiming to understand their collective impact on
urban development. The literature review underscores the current landscape of smart
cities, sustainability, and the emergent role of 5G networks. Highlighting gaps in
existing research, the paper establishes the need for an in-depth examination of the
potential environmental benefits and challenges associated with deploying 5G
technology in smart city infrastructures. A conceptual framework is proposed,
delineating the key components of a 5G Green Network and its seamless integration
into smart city infrastructure. The methodology section outlines research design, data
collection methods, and analytical tools employed to assess the sustainability
implications of 5G technology. The paper examines the various facets of smart city
infrastructure and elaborates on how 5G Green Networks can positively impact energy
efficiency, reduce carbon emissions, and enhance overall sustainability. Drawing on
case studies and examples, the research presents successful instances of cities
implementing 5G Green Networks and analyzes the lessons learned. This research aims
to provide valuable insights for policymakers, urban planners, and technologists alike,
fostering a deeper understanding of the potential of 5G Green Networks in advancing
the sustainability agenda within the context of smart cities.
Health Terminology Standards: A Comparative Study for the Patient Complaint Translation System
Authors: Panchbhai Bhanudas Suresh , Pathak Varsha Makarand
Published: February 2025

When providing an acceptable diagnosis, health terminology helps with the
right usage of language to describe illnesses, ailments, and symptoms in patients. There
could be serious repercussions for the healthcare industry if this specification is
unclear. Uniformity in medical terminology becomes essential when discussing the
integration of automation and artificial intelligence into the scenario. The International
Standards Organization (ISO) states that terminologies should be formal groupings of
concepts that are linguistically unconnected, with a preferred name, suitable synonyms,
and links between the concepts clearly expressed for each concept. To assist decision
support systems, data sharing between health information systems, epidemiological
analysis, research to support health services research, administrative task management,
and other activities, standard terminology should be utilized in an electronic health
record (EHR). This study examines ten popular clinical terminologies, including
LOINC, NDC, and SNOMED Clinical Terms (SNOMED- CT), along with their
histories, purposes, kinds, and structures. They also consist of CDT, CPT, RxNorm,
HCPCS-Level II, and ICD-10, as well as ICD-10-CM, ICD-10-PCS, and ICD-10. Each
criterion's advantages and disadvantages will be considered in this investigation. A
comparative analysis is conducted by analyzing multiple terminologies to identify the
advantages and disadvantages of each one separately.
Nanoparticles for Advancing Cancer Metastases, Diagnosis, and Treatment: Current Progress and Prospective Avenues
Authors: Bhattacharya Sankha
Published: February 2025

In the dynamic realm of cancer research, this chapter explores the
transformative potential of nanoparticles in advancing the diagnosis and treatment of
metastatic cancer. Addressing the multifaceted challenges posed by metastasis, we
delve into the current progress and future prospects of leveraging nanotechnology. The
introductory section illuminates the complexity of metastatic cancer, emphasizing its
significance in cancer-related mortality and introducing nanoparticles as revolutionary
tools. Bridging the organic-inorganic spectrum, we navigate the diverse formulations of
nanoparticles, emphasizing surface precision in design. The chapter unfolds to reveal
precision therapeutics, controlled drug delivery systems, and the integration of imaging
technologies using theranostic nanoparticles. A comprehensive exploration of liquid
biopsy, exosomes, and targeted therapy paints a holistic picture of nanoparticle
applications in battling metastatic cancer. The narrative further probes into the hurdles
of metastasis, the biological barriers, and the strategic use of active and passive
targeting in nanoparticle design. The climax introduces theranostic nanoparticles as
microscopic warriors orchestrating a dual attack on diagnosis and treatment. The
concluding section envisions a future where nanoparticles redefine cancer care,
offering personalized therapies, early detection, and dynamic interventions.
Biomaterials for Bone Tumor: Present and Future Trends in Control and Treatment Strategy
Authors: Patil Saurav , Mukherjee Dhrubojyoti , Bhattacharya Sankha
Published: February 2025

Tumors associated with the osseous system have been a major challenge in
recent decades. There is a tremendous attempt to design and develop biomaterials that
inherit the capabilities to regenerate osteocytes in bone defects induced by surgical
resection and elimination of the residual tumor cells. A biomaterial-based scaffold
should mimic the normal bone tissue during the restoration of bone defects in regard to
hierarchical structure, chemical composition, and biomechanical properties. However,
a considerable number of biomaterials have been developed for bone tissue targeting
with osteogenic, osteoinductive, and osteoconductive properties. Bone tissue-related
research has progressed towards combinatorial therapy such as photothermal therapy,
chemotherapy, and magnetic therapy in orientation with biomaterials which will
elevate the efficacy of bone tumor therapy. New combinatorial approaches with bioimaging and efficient tumor eradication exhibit significant potential for the synergistic
treatment of osteosarcoma. Currently, in the arena of bone tissue engineering, the focus
is on the incorporation of antitumor and pro-bone forming drugs into scaffold matrix
using modified techniques in biomaterials. With the help of these techniques, a
therapeutic material could be unloaded onto a target site precisely which can help in
enhancing the therapeutic outcome and stop the potentially harmful effects on healthy
cells. Multifunctional biomaterials have been proposed for the treatment of bone tumor
cells with a better understanding of biomaterial design and development. To fabricate a
biomaterial-based scaffold more precisely, powerful tools like 3D printing technology
have evolved in the recent past, which can guide the development of scaffolds that
imitate the structural and functional composition of bone which could be helpful in the
treatment of bone tumours and promote osteogenesis. There is a need for the
development of effective targeted drug delivery in corroboration with profound binding
with a suitable biomaterial that can effectively treat bone tumors without any adverse
effect on human physiology. Future research should be in line with combining various
therapies for improved bone tumor treatment and precise control of antineoplastic
drug-oriented treatment oriented with stimuli-responsive systems.
The crime prevention quadrant plan in Chile
Authors: Moreno-Herrera Patricio
Published: February 2025

This study employed the Viable System Model (VSM) to visualize the operational dynamics of a Chilean police station implementing the Crime Prevention Quadrant Plan. It also analyzed crime prevention strategies implemented in Latin America. The findings suggest that the synergies derived from the interconnected systems within a Chilean police station contribute to its viability within the ever-evolving police environment. However, the study also discusses certain limitations of VSM in assessing interpersonal interactions within complex organizations. This necessitates further research into more holistic and integrated approaches to address these limitations. The implications of this research for the Carabineros' organizational policies highlight the critical role of human resources and their intangible capabilities in determining the success or failure of strategies such as the Quadrant Plan.
A Literature Review on Damon Galgut and His Works
Authors: Huang Liping , Hu Zhongqing
Published: February 2025

Damon Galgut is an important representative of contemporary South African literature. Over the past 20 years (2003-2023), scholars both internationally and domestically have conducted extensive research on his works from multiple perspectives, covering aspects such as socio-historical contexts, narrative techniques, and identity. These studies have revealed the multi-dimensional value of Galgut’s works. While international research started relatively late but developed rapidly, focusing on his insights into South Africa’s post-apartheid society and his unique narrative style, domestic research has gradually emerged in recent years, mainly concentrating on his narrative features and thematic ideas. Overall, despite the diverse perspectives, there is still room for further exploration. Future research could further explore the uniqueness and ideological depth of Galgut’s creations and attempt comparative studies with other literary masters to enrich the research horizon of South African literature.
Implicaciones del cuidado de nietos en contextos críticos vulnerables sobre la salud de las abuelas
Authors: Bastidas Erazo Ana Maria
Published: February 2025

Introducción. Los cambios socioeconómicos actuales han llevado a un aumento en la responsabilidad de las abuelas en el cuidado de sus nietos, lo que puede tener un impacto negativo en su salud. Objetivo. Describir las implicaciones del cuidado de nietos en contextos críticos vulnerables sobre la salud de las abuelas de Cali, Colombia (comunas 13 y 14). Método. Utilizando una metodología etnográfica enfocada, durante 9 meses participaron 11 abuelas cuidadoras de nietos de 0 a 6 años. De manera paralela a la recolección de información mediante la observación participante se llevó a cabo entrevistas semiestructuradas y diario de campo. Resultados. Los hallazgos revelan cuatro temas culturales que influyen en la vida diaria de estas abuelas: la historia personal de la abuela, el trabajo doméstico no remunerado, el contexto familiar agresivo y el impacto de las responsabilidades en la salud de la abuela. Conclusión: El cuidado de los nietos en entornos críticos o vulnerables emerge como un determinante social crucial para la salud de las abuelas. La pobreza, la inseguridad y la violencia han traspasado las fronteras del hogar, dejando a las abuelas expuestas a tensiones adicionales. La pérdida de su derecho a participar en las decisiones del hogar puede llevarlas a sentirse marginadas. Es fundamental que  enfermería aborde esta problemática mediante la formulación de planes de mejora específicos, como programas de educación para padres. De esta manera, se pueden implementar estrategias efectivas para apoyar la salud y el bienestar de las abuelas cuidadoras en estos entornos desafiantes
Estructura metodológica de tesis de licenciatura en enfermería en dos instituciones educativas
Authors: Arvizu-Vieyra Naomi Maciel , Alonso-Trujillo Javier , Alonso-Ricardez Abraham
Published: February 2025

Introducción. La Estructura Metodológica (EM) de las tesis desarrolladas con enfoque cuantitativo, es definida como la integración coherente del diseño de investigación, tipo y cantidad de variables, mediciones, tamaño muestral, técnica de muestreo aplicado y plan de análisis estadístico, con la finalidad de dar respuesta a una pregunta de investigación que permita aceptar o rechazar una hipótesis lógicamente planteada. Objetivo. Comparar la EM aplicada en tesis de Enfermería con enfoque cuantitativo realizadas en la FESI y en la ENEO, de la UNAM durante el periodo 2017 a 2019. Metodología. Se realizó un estudio bibliométrico descriptivo, transversal y comparativo. La variable aleatoria se denominó EM mientras que la variable fija se denominó Institución Educativa (FESI y ENEO). Población. Conjunto de estudiantes de la carrera de Enfermería de la FESI y de la ENEO que realizaron tesis. Unidad de análisis. Tesis que se encuentran en resguardo en formato digital y de acceso libre en la Plataforma TESIUNAM de donde se extrajeron 52 para su lectura y análisis. Resultados. De manera general, en ambas instituciones la EM de las tesis puede considerarse similar. Sin embargo, existe mayor diversidad en la ENEO, asi como tesis de mayor complejidad. Conclusión. Las estructuras metodológicas de las tesis en la FESI son frecuentemente básicas a muy básicas. Se observa una tendencia al desarrollo de tesis con estructuras metodológicas complejas a muy complejas, básicamente por la utilización de diseños cuasi-experimentales y experimentales, análisis multivariados, muestreos probabilísticos, tamaños de muestras grandes y planes estadísticos coherentes en la ENEO.
Comentarios sobre la elección de ministros y magistrados por votación ciudadana en México 2025
Authors: Villalobos López José Antonio
Published: February 2025

La Suprema Corte de Justicia de la Nación se contrapuso constantemente a las leyes impulsadas por la Cuarta Transformación, como respuesta ésta impulsó reformas al Poder Judicial de la Federación, que fueron aprobadas en el Congreso de la Unión y publicadas en el Diario Oficial de la Federación el 15 de septiembre de 2024. El objetivo de este ensayo es analizar la elección de los ministros, magistrados y jueces de distrito, a través de votación popular de la ciudadanía; utilizándose una metodología cualitativa, con un enfoque basado en la hermenéutica jurídica. Hasta 2022, el Poder Judicial de la Federación estaba encabezado por 1,671 elementos (11 ministros de la Corte; 7 magistrados del Tribunal Electoral, 910 colegiados, 6 del Consejo de la Judicatura; 737 jueces de distrito). La Corte y sus seguidores declaraban que sus resoluciones jurisdiccionales son tomadas imparcialmente, aunque siempre conllevaron cuestiones ideológicas, políticas y económicas.
Legal reasoning under dialogic and procedural turns
Authors: Encinas Duarte Gabriel Alejandro
Published: February 2025

This article zeroes in on the traits of legal reasoning under the innovations associated with dialogical constitutionalism and procedural turns in adjudication. A critical reconstruction of concepts is followed upon two different crossed oppositions for each development: First, regarding the proposals associated with the dialogical turn, stock is taken of “power” and “voice”-related justifications, as well as formal and informal venues for deliberation. Second, the discussion of a procedural turn in legal reasoning is structured upon the distinction of “system” and “case”-based reasoning, as well as “exclusionary” and “merits-based” reasons. As a result, an explanatory priority is accorded to standards of review which incorporate reasons stemming from deliberative procedures, reinforcing the possibility of democratic control by those subject to decisions. This article is mainly analytical and reconstructive, integrating diverse debates under a common frame. Its main innovation is the proposal of a novel matrix of criteria to compare the diversity of debates related to a dialogic and a procedural turn, within legal reasoning itself. Finally, the different innovations are meant less as an alternative, and more as a supplement to the substantive discussion implied in democratic decision-making.
La época de la democracia, la época del populismo
Authors: Atria Fernando
Published: February 2025

Este artículo discute la relación entre la teoría democrática y las instituciones que pretenden realizarla. Dada la relación entre ambas, en toda explicación de las instituciones democráticas es posible leer, a pesar de sus autores incluso, una teoría de la democracia y viceversa. Este punto es ilustrado por una comprensión “realista” de la democracia, usando como ejemplo la defendida por Hans Kelsen en su Esencia y valor de la democracia. La crítica “populista” a la democracia realmente existente tiene una inesperada continuidad con una teoría realista como esa. La pregunta entonces discutida es si esa continuidad muestra algo acerca de la imposibilidad de la democracia en nuestra época, que sería por eso la época del populismo.
Aldose Reductase Inhibition, Molecular Docking, and Density Functional Theory Studies of Dinaphthodiospyrol H from Diospyros kaki (Japanese Persimmon)
Authors: Rauf Abdur , Naz Saima , Ahmad Zubair , Rashid Umer , Marryum  , Ayub Khurshid , Aetizaz Muhammad , Soonmin Ho , Muhammad Naveed , ur-Rehman Mujeeb , Alsanie Walaa F. , Alamri Abdulhakeem S.
Published: February 2025

This study explores the aldose reductase (AR) inhibitory potential of dinaphthodiospyrol H, a compound isolated from Diospyros kaki (Japanese persimmon). Aldose reductase plays a crucial role in the polyol pathway, a key factor in the progression of diabetic complications such as neuropathy and retinopathy. The isolated compound demonstrated the maximum AR inhibitory effect followed by the tested extract such as 87.34% and 49.09%, respectively. The AR inhibitory effect was supported by molecular docking studies highlighting its strong binding affinity to the AR active site. Complementary Density Functional Theory (DFT) analysis further elucidated the compound’s electronic properties, confirming its stability and effectiveness as an AR inhibitor. Docking studies carried out on the 3D crystallographic structure of Aldose Reductase; ALR2 (PDB ID = 2FZB) showed significant hydrophilic interactions with amino acid residues Ala299, Leu301, Ser302 and hydrophobic interactions with the Trp219. The findings suggest that dinaphthodiospyrol-H holds significant promise as a lead compound for developing novel therapeutic agents targeting diabetic complications through AR inhibition.
Integrated Pothole Detection and Damage Assessment Model for Road Analysis
Authors: Jain Riya
Published: February 2025

Potholes and unmaintained pavements lead to dis- rupted transportation that becomes unsafe and more costly to
maintain. Repairing damage takes these prices up, delays traffic, and brings about a higher accident risk for the so-called most
vulnerable road users, such as cyclists and motorcycle riders. They also affect travel and logistics, thus the dire need for
monitoring and timely remedies. The usual manual techniques such as the surface distress index have been used in road damage
assessment. However, it is limited with respect to human endeavor and time and scalability. They include automated
techniques for analyzing the road surface. Examples of successful methods adopted are the K-Nearest Neighbours (KNN)[21]
coupled with the Gray Level Co-occurrence Matrix (GLCM)[20] to detect and classify road defects. Likewise, Support Vector
Machines (SVMs) have been used effectively in classifying potholes, using partial differential equations for image segmentation.
However, although these methods may work well, they have limitations, such as being very dependent on the datasets and being
sensitive to the lighting conditions during capture. Recent advances in deep learning, such as the family of models of You
Only Look Once (YOLO)[12], have provided good opportunities to improve these pothole detection systems concerning speed and
accuracy. This work aims to continue by improving the process of pothole detection and segmentation for greater efficiency,
wider applicability to the detection of potholes, and more accurate damage assessments. This ultimately facilitates effective
repairs and maintenance processes.
Enhanced hybrid classification model algorithm for medical dataset analysis
Authors: Kumar N. , T. Christopher
Published: February 2025

The medical industry generates a significant volume of data that requires effective machine learning models to make accurate predictions for public healthcare. Current Machine Learning (ML) techniques have limitations in feature extraction and classifier accuracy. In this paper using diabetes dataset classification, to address these issues, propose a novel algorithm that enhances Hybrid Classification Model approach by integrating advanced methods tailored for high-dimensional medical data. To handle Missing Values (MV) and outliers, a hybrid imputation approach that combines K-Nearest Neighbor (KNN) and Multivariate Imputation by Chained Equations (MICE) is initially used to preprocess the datasets. Feature extraction (FE) is performed using Deep Feature Extraction techniques, including Convolutional Neural Networks (CNNs) and Autoencoders, followed by Feature Fusion to create a comprehensive feature set. For Feature Selection (FS), introduce an Advanced Ensemble Feature Selection method employing Genetic Algorithm-Based Feature Selection (GAFS), Multi-Objective Evolutionary Algorithm (MOEA), and Relief-Based Methods to identify the most relevant features. Finally, classification is achieved through a Hybrid Classification Model incorporating Ensemble of Classifier with Stacked Generalization (Stacking), Boosting, Bagging and Neural Network (NN) Enhancements with attention mechanisms (AM) and Transfer Learning (TL). This integrated approach enhances the robustness and accuracy of medical data classification. Comparing the suggested approach with current methods, the experimental outcomes show a considerable improvement in accuracy (A), sensitivity (S), specificity (SP), and reduced execution time (ET).
Integrated insect pest management of tropical forest insect pests: an eco-friendly approach
Authors:   ICFRE-Rain Forest Research Institute, Jorhat (Assam) – 785010 (India), Kulkarni Nitin
Published: February 2025

Forests in India contribute one of the principal natural resources even with mere coverage of 21.71% or 7,13,789 sq km (ISFR, 2021) of the total geographical area. Vegetation also varies from tropical evergreen in Andaman and Nicobar Islands to dry Alpine forests high up in the Himalayas. Insect pests, which form an integral part of the existing ecosystem, are also the major biological determinants influencing development and destruction of forest and its forest products from seeds in stands to timber in depots, besides medicinal plants as minor forest produce. Unlike agriculture, longer gestation period crops, make it difficult to make frequent assessments of the revenue losses caused by forest insect pests in a vast and diverse country like India. However, as per an estimate in 1950s, forestry insect pests cost Rs.53.70 million (10% of the total revenue, which was 537 million at that time).

The tropical forests are found between Tropic of Cancer (23.5°N latitude) and the Tropic of Capricorn (23.5°S latitude). They occupy 10% of the total land mass of the world above sea level. Tropical forest cover approximately is about 1,700 million hectares of geographical area (FAO, 1993), under the political barriers of more than 90 countries of North America, Central America, South America, Caribbean, Central Africa, East Africa, West Africa, Southeast Asia including India, under the tropical region (Redublo, 2016). Most of these are the biodiversity hotspots with similarly diverse entomofauna, as high as 30 million living species, which includes beneficial and insect pest fauna.

Insects have their essential roles in forest ecosystem processes, such as facilitating removal of weakened trees, decomposition of dead or decaying trees, nutrient cycling, biodiversity maintenance, and forest regeneration and succession. However, their population outbreak is a major biotic disturbance (FAO, 2007; Sambaraju et al., 2024). Insect pests infesting forest trees at various stages, viz., inflorescence, fruits, seeds on standing trees and storage (Kulkarni and Joshi, 1998), seedlings in forest nurseries (Thakur, 2000), plantations and natural forests (Kulkarni, 2014) in India have earlier been compiled. With global perspective, Wylie and Speight (2012) have compiled an excellent book describing a number of insect species.

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BRUTA AVENTURA EM VERSOS OU ANA CRISTINA CESAR À LUZ DOS SPOTS:
Authors: Cintra Elaine Cristina , Pontes Brenda
Published: February 2025

O presente artigo tem como objetivo observar e discutir as relações entre o documentário Bruta aventura em versos, de Letícia Simões (2011), e a poesia e crítica de Ana Cristina Cesar, buscando interpretar como se relacionam as múltiplas vozes presentes no documentário com a voz de Cesar. Para tratar da poeta, o documentário apresenta interpretações sobre a poesia de Cesar, desenvolvidas por amigos próximos à poeta e por seus leitores, e a própria biografia da autora torna-se objeto da discussão, o que faz o documentário transitar entre os espaços da ficção e da biografia – processo que também ocorre em sua poesia, a qual recorre a recursos da autobiografia, como a sua fortuna crítica discutiu em vários trabalhos. Para esse estudo, inicialmente pontuamos alguns dos aspectos do gênero documentário, o que nos auxiliou na discussão da construção da persona crítica, além da persona poética presentes em Cesar, ambas evocadas no filme. Nossas referências teóricas são estudos que tratam do gênero documentário, como Bill Nichols (2005), e de estudos sobre a autobiografia na literatura, como Lejeune (2008), Achcar (1994) e Arfuch (2010). Mais especificamente, para tratar de Cesar e sua escrita, temos como respaldo autores como Carlos Eduardo Souza (2009) e Flora Süssekind (2004), entre outros.
EM BUSCA DA TRADIÇÃO PERDIDA
Authors: De Lima Marcelo , Barros Patricia Marcondes de
Published: February 2025

O objetivo deste trabalho é analisar o romance distópico Soumission (2015), do escritor francês Michel Houellebecq, sob perspectiva política, considerando a trajetória do protagonista François, que testemunha uma profunda transformação da França – de laico a religioso – com a eleição de seu primeiro presidente muçulmano, num pleito imaginado em 2022. O artigo sustenta que o romance, que dialoga com a literatura distópica contemporânea, revela uma sensação de esgotamento diante do liberalismo secular e evidencia um sentimento de nostalgia quanto a valores ditos tradicionais, selecionados na longa trajetória da cultura da Europa ocidental, relacionados à religião e ao patriarcado, que ironicamente se coadunam com o projeto de poder representado no livro pelo governo mulçulmano, conforme a visão do narrador. Neste texto, interpretamos o romance à luz do conceito de retrotopia do sociólogo Zygmunt Bauman (2017), para quem existe, hoje em dia, um sentimento difuso de retorno ao passado como mecanismo de defesa frente a um mundo em constante transformação e conflito. O artigo é dividido em três segmentos: no primeiro, fazemos um breve contexto das tensões políticas da França atual; no segundo, fornecemos uma visão geral de obras de Houellebecq que dialogam com essas tensões; na parte final, analisamos o romance Soumission utilizando o conceito de retrotopia de Bauman.
A FILOSOFIA DO PROGRESSO E O DEVIR DA HISTÓRIA:
Authors: Pereira João Batista
Published: February 2025

Este artigo visa a refletir sobre a influência do mito na elaboração do ensaio “O narrador. Considerações sobre a obra de Nikolai Leskov”, de Walter Benjamin, no qual o declínio dos relatos orais é atribuído ao advento da modernidade. Conjecturamos que essa afirmação tem antecedentes míticos, relacionados a dois pressupostos: aos princípios materialistas, conforme foi indicado por Michael Löwy (2020), e à Lebensphilosophie, condicionada ao que foi preconizado por Ludwig Klages (1929). Em grande medida, essas duas perspectivas foram motivadas pela idealização do passado de sociedades pré-industriais, recurso que se revelou como um caminho para Benjamin questionar a filosofia do progresso, que instava à dissolução da vida comunitária e à decadência das relações sociais. Sugerimos que a reverência ao passado foi ao encontro do mito, notadamente, nos períodos em que Benjamin esteve autoexilado em Ibiza, nos anos 1930, como indicado em pesquisas realizadas por Vicente Valero (2017). Em nossas conclusões pudemos identificar que, na insólita ilha espanhola, as casas primordiais, os rudimentares meios de produção e os modelos de vida dos seus habitantes endossaram uma utopia profana na leitura benjaminiana, que cultivou a expectativa de irromper um devir que interviesse na história, afiançado na esperança da ação humana transformar a realidade.
Liberdade de expressão e “filtragem” de conteúdos na Política do Audiovisual:
Authors: Rodrigues Raimilan , Tassigny Monica
Published: February 2025

O tema do artigo situa-se no campo das investigações das tensões entre a concretização do direito à liberdade de expressão artística e a realização das políticas públicas. Foi realizado estudo de caso a respeito de medida realizada em 2019 pelo presidente da república Jair Bolsonaro, que ao anunciar filtro sobre conteúdo das obras artísticas, suspendeu chamada pública de projetos em curso na ANCINE. O objetivo do estudo foi avaliar o conteúdo da decisão governamental que pretendeu implementar o “filtro” anunciado sobre a política do audiovisual; e, como objetivo específico, analisar a atuação das instituições envolvidas no conflito e paradigmas teóricos para casos futuros. Adotou-se como metodologia estudo de caso, pesquisa documental e bibliográfica a partir do estudo da ANCINE ocorrido em 2019. Os resultados obtidos foram os de que, a despeito da instituição incumbida da última palavra não haver chegado a um paradigma para decisões futuras, houve efetiva atuação das instituições no jogo democrático, ao lado da deficiência do órgão incumbido do papel de fiscal da lei. O filtro anunciado não restou implementado no caso analisado. As discussões das instituições estruturaram-ainda se sob padrões tradicionais a respeito da discricionariedade nas políticas públicas.
Cartografia de pesquisas sobre divulgação científica
Authors: Lopes Cristovão Vera Lúcia
Published: February 2025

A divulgação científica como constitutiva dos letramentos acadêmico-científicos (LAC) e sua relevância para acionar a relação da ciência com a sociedade são pressupostos para este trabalho de pesquisa. Meu objetivo foi mapear estudos sobre divulgação científica no campo dos estudos de letramentos acadêmico-científicos, da escrita acadêmica e/ou de gêneros textuais/discursivos para perscrutar se a pesquisa em DC tem constituído esse campo. Por meio de uma metapesquisa, vinte e nove dossiês foram examinados, levando-nos ao resultado de doze pesquisas identificadas e cinco inserções teóricas nos ensaios introdutórios/editoriais. Nesses dezessete textos, identifiquei elementos como objeto de análise, construto teórico, categorias de análise e se há reflexão ou discussão relacionada aos LAC. Na síntese dos resultados, procurei chamar a atenção para esse último elemento, ou seja, a presença ou ausência dessa reflexão, na defesa de que a DC constitui e contribui para LAC. A maioria dos trabalhos identificados se voltou para a análise de exemplares de textos de diferentes gêneros de DC, sendo que alguns justificam tal foco para instrumentalizar o ensino (de leitura e de escrita por meio de gêneros) com referências sobre sua composição devido à sua urgência e à sua relevância para a relação ciência, educação e sociedade.
NO ENQUANTO DA AÇÃO
Authors: Simões Itamar Wagner Schiavo
Published: February 2025

O texto apresenta uma reflexão sobre a ação física como fabulação criadora em interlocução entre teoria e prática. A ação física é investigada em experimentações com estímulos e em diálogo com o conceito de obra de arte como bloco de sensações. Esse é o ponto de partida para pensar a ação enquanto fabulação, circunstância qualificada como uma vidência, em que estados afetivos se tornam matéria expressiva. Ao analisar o processo criativo, enfoco as conexões sensoriais e o fluxo orgânico que emerge em uma sítio-ação de experiência, tempo-espaço de produção de singularidades. Esta, por sua vez, é refletida na perspectiva da fabricação de lembranças pelo si-outro afetado pelas potências de realidade, nos regimes do novo possível.
O FOMENTO É PARA TODOS?
Authors: Trotta Rosyane
Published: February 2025

O artigo se origina de pesquisa sobre o teatro de grupo na cidade de São Paulo que tem como critério a gestão coletiva dos modos de produção e criação. Na presente abordagem, toma-se a questão da formação de público segundo os estudos (Camargo Costa, Pupo e Romeo, entre outros) que se dedicaram à análise dos resultados da política cultural vigente de 2002 a 2012. Busca-se compreender que tipo de teatro e de pedagogia teatral emergiu com a Lei de Fomento e foi estrangulado com adulteração de sua aplicação.