bluuebunny/crossref_metadata_2025 huggingface dataset:
Behavioural Characteristics of Children with Developmental Disorder Risks
Authors: Lavrova M , Suleymanova E , Lvova O , Solominova A
Published: May 2020

The article is devoted to the study of the temperament and behaviour of children with developmental disorder risks. Early age is most significant in terms of early identifying deviant development markers for implementing effective programmes for early intervention. The article deals with the peculiarities of using the Infant Behaviour Questionnaire - Revised (IBQ-R) and its application in scientific research; the results of domestic and foreign research into temperament as a marker/predictor of deviant behaviour are presented. The paper describes the results of a pilot study of differences in behaviour in a sample of 49 children aged 5.6 months. The research involved two groups of test children, a reference group (typically developing children) and the children of developmental risk groups (which included prematurity, family risk of autism spectrum disorders (ASD)/attention deficit and hyperactivity disorder (ADHD), paediatric arterial ischemic stroke). The significant impact of developmental disorder risks on the Perceptual Sensitivity Scale (IBQ-R) as well as the effect of sexand risks on the Approach, Vocal Reactivity (IBQ-R) scale were discovered. There are suggestions that prematurity may have a negative impact on the development of temperament in children aged 6 months. However, in comparison with such factors as the genetic predisposition to atypical development or local brain damage due to paediatric arterial ischemic stroke, prematurity (excluding extremely premature) probably has less influence on the development of temperament and behavioural characteristics. There is a significant heterotypic continuity of individual differences in temperament indicators at an early age, which highlights the need for further research into the issue and the formation of large cohorts of children.
Keywords: deviant development markers, behaviour, IBQ-R questionnaire.
Machine Learning Technologies and Psychological Testing of Pre-School and Primary School-Aged Children in Diagnostics of Perinatal Affection of the Central Nervous System
Authors: Piyanzin A , Ashkinadze A , Akinina Z , Romanova O
Published: May 2020

The present study deals with computer-assisted learning technologies used for the analysis of psychological test results of children to diagnosis perinatal affection of the central nervous system. The mathematical models of logistic regression and gradient boosting give the best results within the accuracy of 81%.
Keywords: Machine learning, children, central nervous system, perinatal affection.
Association between Emotional Intelligence and Hemispheric Activity Asymmetry
Authors: Razumnikova O , Khoroshavtseva E , Yashanina A
Published: May 2020

The relations between the asymmetry of hemispheric activity using the EEG rhythms in resting and both trait emotional intelligence (EI-IPIP) and self-assessment of emotional reactivity on IAPS stimuli were studied in university students. The obtained EEG patterns of power asymmetry in both low-frequency and high-frequency indicate different variants of the hemispheric dominance in the anterior and posterior regions of the brain, depending not only on the valence of induced emotions, but also on selfassessment of perception or expression of emotional states. Total EI was associated with relatively greater left frontal activation on low frequency delta oscillations and on higher beta2 oscillations in posterior cortex. Using EEG mapping positive relations were found between the right hemispheric delta rhythm and emotional reactivity to negative emotive stimuli and between the left hemispheric delta and positive affect. Self-rating of positive to negative emotion during both EI and IAPS stimuli-induced affect testing was more pronounced in the relationships to asymmetry of hemispheric activity than separate traits EI.
Keywords: Emotional intelligence traits, self-assessment of emotional reactivity, EEG, hemispheric asymmetry, frequency bands
Socio-Biological Risk Factors for ADHD
Authors: Shevchenko I
Published: May 2020

The aim of this article was to show the relationships of socio-biological factors in the development of the child with ADHD with the degree of severity of the defect. As we tend to assume, both social and biological factors (together or separately) are not selective for the development of certain cognitive functions (for example, the early debut of the disease for the non-formation of control functions or pregnancy complications for the non-formation of auditory memory), and globally, in aggregate, influence the mental development of the child. The study allowed us to establish risk factors in which we can talk about the possibility of developing and aggravating ADHD, identify opportunities for its prevention and confirm the importance of early complex neuropsychological remediation in the treatment of the disease.
Keywords: ADHD, socio-biological characteristics of the development, ADHD risk factors.
Psychological Mechanisms of Cultural, Clinical and Individual Transformations of Mentalization
Authors: Sokolova E
Published: May 2020

The subject of theoretical revision is the impairment of social cognition, which is wellknown in the clinics of borderline personality disorders. Mentalization is understood as a form of social cognition, which allows to perceive, imagine and emotionally relate, make sense and causality of what’s happening in a subjective world – of self and another person. Mentalization supposes integration of contextual factors, material and physical aspects of situation and behavior, as well as inner subjective feelings, beliefs, goals and intentional states as representative motives for a given behavior. In the perspective of the cultural-historical theory and methodology by L.S. Vygotsky a new interpretation is offered for the clinical phenomena of mentalizationdeficit, an understanding is given for transformation of its structure and functions as a consequence of the person’s loss of interpsychic social connections and disintegration of intrapsychic organization of consciousness, impairment of its systemic structure, narrowing and simplification of cross-functional bonds and intrapsychic “mythology”. In the result of this double destruction of bonds, ontogenetically early and primitiveforms of mentalization are «splitting off», isolated and start holding a domineering position in psychic functioning. The process of mentalization regresses to its pre-categorical and cognitive-affective non-differentiated levels and structures (syncretic and complex organization), unfolding involuntarily and unconsciously, lacking meaningful coherence, symbolic mediation and focus for understanding thesubjective world – of self and the Other. The unconscious substitution of the psychic picture of the inner world with impulsive actions, hypochondriac and narcissistic fixations, autistic pseudo-mentalization and manipulation is lacking the meaningful and sanguineous dialogue with the Other. The loss of social connections (interpsychic communication), without being mediated by the addressed to the Other speech dialogue is interiorized into the inner “muteness” – the loss of not only understanding of others, but the interruption of meaningful inner and “worded” dialogue with the self, self-understanding.
Keywords: mentalization disorders, cultural-historical approach, structure-functional disorganization.
Narrativity Analysis in Alzheimer’s Disease
Authors: Thomas P , Billon R , Hazif-Thomas C
Published: May 2020

Context. Alzheimer’s Disease (AD) is a neurodegenerative illness with frequency of occurrence increasing with old age. If memory impairment setting progressively in is here an element associated upfront, other neurocognitive troubles are also associated, for example, language impairment which can degenerate into aphasia. Aim of the study. To evaluate semantic and textual impairment in AD. Methods. Populationsstudied concerned 151 AD patients in consultation at Brest University Hospital. Certain sociodemographic data (sex, age, cultural levels) were collected as well as results from neuropsychological tests: (Folstein – MMSE; Dubois’s 5-word test; fluencies, Dubois’ s frontal test battery; Cornell’s scale for depression; Barbizet’s test, “The Lion’s tale”, for textual analysis. Demented patients were composed of 102 females and 49 males of average age 80.3 ± 6.91. All the tests, including the number of items memorized latterly in the Barbizet’s test are impaired all the more by Folstein’s test being altered. The formal fluency on demented patients is less impaired than the semantical lexical fluency test (scored respectively 5.74 ± 1. 09 versus 4.41 ± 2. 19;t= 5.60, p<0.01). The studied demented cohort shows more intrusions (n=36) than inversions in the delayed Lion’s tale, whether for items or for episodes in which they occur (n=19). The regressive PLS analysis shows that for the explanation of the overall scores to do with “The lion’s tale”, calculated later, only attainment of lexical fluency has any notable influence (Regression coefficient CR=0.224) or, more accessorily, the cultural level (CR=0.12). Conclusions. Attainment of category fluency and patient culture levels have effects on narrativity.
Keywords: Alzheimer’s Disease, semiotics, semantics, textuality
A Methodology for Developing Transprofessionalism in Engineers in the Conditions of Post-Industrial Society
Authors: Zeer E , Symanyuk E
Published: May 2020

The relevance of the problem under consideration is conditioned by the changes in socio-economic conditions and the socio-technological development of the Russian economy, which has significantly altered the world of professions in the post-industrial society: some professions are disappearing, some are transforming, and others are appearing. Along with the traditional concepts of ”profession” and ”specialism”, a new term has been recently established in the field of professional studies: ”transfession”, referring to a kind of labour activity realised based on synthesis and convergence of professional competences belonging to different specialist fields. The main professional characteristic of transfessions is transprofessionalism - the ability toperform a wide range of specialised activities. The identification of socio-humanitarian technologies for the development of this integral capacity of professionals in the system of continuous education determines the relevance of this study. The purpose of the article is to analyse and generalise the grounds and prerequisitesfor transprofessionalism as an integral quality of the subject of technical professions in a dynamically changing social and professional environment. The main methods in the study of this problem are theoretical and methodological analysis of the research subject and the research problem based on studying and logically generalising scientific research literature, as well as hypothetical-inductive and project methods. The description of the phenomenon of transprofessionalism was made relying on multidimensional, transdisciplinary, network and project approaches. The article presents the scientific definition of transprofessionalism, its meaningful content, as well as criteria of transprofessionalism manifestation in a dynamically changing social and professional environment. The relevance of the phenomenon of transprofessionalism is substantiated understood as requirements to the subject and its integral quality, which implies qualitatively new content and technological training for professionals in technical fields. In particular,it is stated that in the course of post-industrial society development the concept of “profession” loses its original meaning as a field of social division of labour, and transprofessionals capable of performing a wide range of professional activities become competitive and popular on the employment market. The article may be of interest to methodologists, researchers, teachers and those involved in continuing professional education.
Keywords: methodology, transprofessionalism, subject of technical professions, logical and semantic model and platform for the development of transprofessionalism, high humanitarian technologies.
MIDDLE EAST LINK OF TERRORIST THREATS FROM THE PERSPECTIVE OF PESANTREN IN INDONESIA: CASE STUDY IN THE AREA OF MALANG
Authors: Yumitro Gonda , Abdullahi Abdelsalam Elfatih , Farhana Mohamad Shukri Syaza
Published: May 2020

Purpose of the study: This article elaborates on the perspective of pesantren towards the Middle East link of the terrorist threat in Indonesia and their notion on the policies conducted by the Indonesian government, especially in the area of Malang.
Methodology: This research is qualitative research by in-depth interviews, literature reviews, and focus group discussion (FGD) collecting data methods. The objects of this research were several pesantren leaders from different backgrounds such as Al Irsyad, Hidayatullah, Muhammadiyah, the Muslim Brotherhood, Nahdatul Ulama (NU), and Salafi. The data were analyzed using Nvivo 12 Plus and discussed with various literature reviews to perform the finding.
Main Findings: The pesantren considers that increasing cooperation between state agencies and groups that are judged as having a link to sources for radical ideology in the Middle East would help minimize the problem of radicalism and the threat of terrorism in Indonesia, especially in the Malang area. Therefore, in assessing and deciding various policies on Islamic terrorism, the government needs to consider the Islamic discourse as not to be misled by public opinion.
Applications of this study: This study is helpful for the government to evaluate its policies to face the issues of terrorism by understanding the Middle East link of terrorism in Indonesia based on the perspective of pesantren. Moreover, ina terrorism study, this article can be a reference source to analyze the issues.
Novelty/Originality of this study: The growing terrorism in Indonesia is often associated with pesantren as these institutions are assumed to have the potency of supporting radicalism. Moreover, they have an ideological and network connection with the Islamic movements in the Middle East. On the other hand, pesantren is claimed to be a means of spreading peaceful Islam and is ready to cooperate with the government in handling the issue of terrorism in Indonesia.
The relationship between corporate governance and corporate social responsibility
Authors: Veres Edit
Published: May 2020

Corporate governance (CG) is a corporate governance system for large companies which includes policies and procedures for corporate social responsibility (CSR). The present study examines the relationships between CG and CSR, and analyzes the studies that separate or combine the explanation of the two concepts.CG can be interpreted as the relationship between governors and stakeholders. Angyal (2009) and Auer (2017) agree that the two phenomena coexist and are connected at several points. The goals of the two phenomena are intertwined, compliance with other important requirements (environmental, labor law) besides the primary corporate goal. CG is a system based on the sharing of power and roles between owners, management and boards (board, supervisory board). The roles of ownership, supervision, and control are separated. The division of power means that the boards keep the management under strict control and the owners can account for the boards (Tasi, 2012). According to Tasi (2012), responsible CG involves careful management; financial planning and implementation; control mechanisms for the operation of the company; company transparency and business ethicsissues; publicizing corporate information and corporate social responsibility policies and practices. Angyal (2009) sees that CG and CSR are intertwined “neither intersection, nor intersection, nor parallelism, but coexistence”. (Angel,2009: 14). It does not agree with the incompatibility of corporate governance or corporate governance and social responsibility, in practice the former two are more common. Corporate governance encompasses corporate social responsibility policies, procedures, and can be interpreted as the relationship between governors and stakeholders. The authors of the studies analyzed agree that the two phenomena coexist and are connected at several points. The goals of the two phenomena are intertwined with compliance with other important requirements (environmental, labor law) besides the primary corporate goal.

JEL Classification: G30; G39, M14
COVID-19 e os Danos Invisíveis: O Papel do Médico de Família
Authors: Gouveia Maria
Published: May 2020

N/a.
A Inovação Ambiental em Laticínios Sob o Olhar dos Gestores
Authors: Barbosa Bruna Borges de Castro , Pereira Michele Morais Oliveira , Antunes Luiz Guilherme Rodrigues , Antonialli Luiz Marcelo , Ferreira Michelle Cristina
Published: May 2020

O presente estudo teve como objetivo analisar a visão dos gestores de laticínios sobre a inovação ambiental nas respectivas indústrias. Os dados foram coletados por meio de entrevistas semiestruturadas e analisados por meio da análise de conteúdo. Identificou-se o conhecimento que esses gestores têm sobre o assunto, quais os planos e as ações voltados a esta forma de inovação, as barreiras encontradas nesse sentido e as estratégias de enfrentamento a essas barreiras quanto à inovação ambiental. As indústrias de laticínios avaliadas estão inovando ambientalmente, porém os gestores apresentaram pouco conhecimento sobre o assunto. Os gestores alegaram a necessidade de contratação de uma empresa especializada na área de gestão ambiental para execução de programas ambientais e serviços de supervisão, indicando dificuldades no que concerne ao conhecimento interno para esta forma de inovação.
Antecedentes e Consequentes do Valor Percebido em Usuários de Smartphone
Authors: Correia Lima Regina Cellis De Azevedo , Mainardes Emerson Wagner , Dovera Isabelle Menezes
Published: May 2020

O presente objetivou verificar a influência de atributos de motivações hedônica, utilitária e social no valor percebido de usuários de smartphones, bem como investigar o impacto do valor percebido no boca-a-boca positivo e na intenção de recompra de usuári, o de smartphones. Para tanto, propôs-se um modelo no qual o valor percebido é formado pelo prazer percebido, utilidade percebida, facilidade de uso percebida e norma subjetiva, sendo o valor percebido determinante no boca a boca positivo e da intenção de recompra. A amostra final válida foi constituída por 394 respondentes. Para a análise, foi utilizado o método de Modelagem de Equações Estruturais (MEE). Os resultados evidenciaram que smartphones que despertem o prazer e demonstrem a utilidade e facilidade de uso possivelmente serão percebidos como mais valiosos aos seus usuários. Ademais, evidenciou que a percepção de valor possivelmente conduzirá o consumidor a manter o relacionamento com a marca no futuro como também levar a compartilhar informações sobre essa experiência.
DOĞRUDAN YABANCI YATIRIMLARIN BARRO SEFALET ENDEKSİNE ETKİSİ: TÜRKİYE İÇİN SVAR ANALİZİ
Authors: ERGİN ÜNAL Ayşe
Published: May 2020

Bir ülkenin
makroekonomik performansının takip edilip incelenmesi, gerek ekonomi
politikalarının etkinliğini ölçme gerekse de ekonomik birimlerin yatırım
kararlarını etkilemesi açısından önem arz etmektedir. Bu çalışmanın amacı,
doğrudan yabancı yatırımların (DYY) enflasyon oranı, işsizlik oranı, faiz oranı
ve ekonomik büyüme oranı verileri ile hesaplanan Barro Sefalet Endeksi
üzerindeki etkisini Türkiye için incelemek ve analiz etmektir. Bu amaç
doğrultusunda 1985-2017 dönemi için Barro Sefalet Endeksi hesaplanmış olup, DYY
arasındaki ilişki SVAR modeli ile analiz edilmiştir. Analiz sonucunda, DYY’nin GSYİH
içindeki payı ile reel döviz kuru eş anlı şoklarının,  Barro Sefalet Endeksi’ni negatif yönde
etkilediği tespit edilmiştir.
AVM ATMOSFERİ UNSURLARININ ALIŞVERİŞ DEĞERİ VE TÜKETİCİLERİN ALIŞVERİŞ DAVRANIŞ BİÇİMLERİ ÜZERİNDEKİ ETKİSİ: ALIŞVERİŞ DEĞERİNİN ARACI ROLÜNÜN İNCELENMESİ
Authors: SAĞLAM Mehmet
Published: May 2020

Bu çalışmada, AVM atmosferi unsurlarının, hazcı ve
faydacı alışveriş değerleri üzerindeki etkisi ile alışveriş davranış
biçimlerinden plansız zaman geçirme, plansız alışveriş yapma ve müşteri olma
niyetleri üzerindeki etkisi, çoklu regresyon analizi ile incelenmeye
çalışılmıştır. Ayrıca, AVM atmosferinin alışveriş davranış biçimleri üzerindeki
etkisinde hazcı ve faydacı alışveriş değerlerinin aracı rolü hiyerarşik
regresyon analizi ile araştırılmıştır. Çalışma, online anket aracılığıyla ve
kolayda örnekleme ile 330 katılımcı üzerinde gerçekleştirilmiştir. Veri
analizinde SPSS 24 ve AMOS 21 programı kullanılmıştır. Analiz sonuçlarında AVM
atmosferi unsurlarından dizayn, sosyal ve ambiyans faktörlerinin hazcı değer
üzerinde pozitif, dizayn faktörünün faydacı değer üzerinde negatif, yerleşim ve
sosyal faktörlerin ise pozitif etkiye sahip olduğu, dizayn ve ambiyans faktörlerinin
plansız zaman geçirme üzerinde pozitif, sosyal ve ambiyans faktörlerinin
plansız alışveriş yapma ve müşteri olma niyeti üzerinde pozitif etkiye sahip
olduğu, sosyal faktörlerin plansız alışveriş yapma, ambiyans faktörlerinin ise
müşteri olma niyetinde daha fazla etkisi olduğu belirlenmiştir. Aracı etkiler
değerlendirildiğinde, AVM atmosferinin plansız zaman geçirme ve müşteri olma
niyeti üzerindeki etkisinde hazcı değerin kısmi aracı etkiye, plansız alışveriş
yapma üzerindeki etkisinde ise tam aracı etkiye sahip olduğu, faydacı değerin
ise sadece AVM atmosferinin müşteri olma niyeti üzerindeki etkisinde kısmi
aracı etkiye sahip olduğu sonucuna ulaşılmıştır.
SERMAYE-YOĞUN MAL İHRACATINDA REKABET GÜCÜNÜN BELİRLEYİCİLERİ: TÜRKİYE İÇİN YAPISAL KIRILMALI BİR ANALİZ
Authors: YANAR Rüstem , ÇELİK Hüseyin
Published: May 2020

Balassa (1965) tarafından ortaya konulan Açıklanmış Karşılaştırmalı Üstünlükler (RCA), uluslararası ticaret rekabet gücü analizlerinde yaygın olarak kullanılmaktadır. RCA, bir ülke veya bölgenin bir sektör için ya da ekonominin geneli için uluslararası rekabet gücüne sahip olup olmamasını araştırmaktadır. Ancak literatüre bakıldığında RCA ile elde edilen rekabet gücünü belirleyen faktörler pek incelenmemiştir. Bu çalışmanın amacı ise, açıklanmış karşılaştırmalı üstünlükler (RCA) ile elde edilen Türkiye’nin sermaye yoğun mallardaki rekabet gücünü etkileyen faktörleri zaman serileri analizi ile araştırmaktır. 1989-2017 dönemini kapsayan çalışmada Zivot ve Andrews (1992) yapısal kırılmalı birim kök testi, Gregory ve Hansen (1996) yapısal kırılmalı eşbütünleşme testi ve FMOLS katsayı tahmin yöntemi kullanılmıştır. Yapılan analizler sonucunda modele dâhil edilen makroekonomik göstergelerle sermaye yoğun malların rekabet gücü arasında uzun dönemli ilişki olduğu görülmüştür. Katsayı tahmin sonuçlarına göre GSYİH, döviz kuru ve doğrudan yabancı sermaye yatırımlarının sermaye yoğun malların uluslararası rekabet gücünü pozitif etkilediği fakat patentlerin negatif etkilediği sonucu elde edilmiştir.
The Scripps Dike and Its Implications for Mid‐Miocene Volcanism and Tectonics of the California Continental Borderland
Authors: Day James M.D. , Koppers Anthony A.P. , Mendenhall Brendon C. , Oller Brian
Published: May 2020

New field observations, petrology, geochemistry, and 40Ar/39Ar geochronology are reported for the Scripps Dike, which crops out at the coast north of La Jolla, California. The northeast–southwest-trending and laterally discontinuous dike has a basaltic–trachyandesite bulk composition, with an emplacement age of 13.89 ± 0.13 Ma. Modeling of the dike composition indicates that it formed from 0.5 to 1.5% partial melting of a primitive mantle-type source, metasomatized by slab fluids, predominantly in the garnet stability field. The composition of the dike, including relatively high MgO (6.6 wt.%) and Sr/Y (~105), makes it akin to magnesian andesites in Baja California, Mexico, termed “bajaites.” Field evidence indicates that the current exposure of the dike is close to the original stalling depth, it was probably associated with explosive volcanism, and the dike flowed laterally. After accounting for alteration, the dike has an initial 87Sr/86Sr composition of 0.70390, with limited evidence for crustal contamination, consistent with derivation from a slab-fluid-metasomatized mantle source. The composition of the dike places it broadly in the range of Miocene California Continental Borderland (hereafter referred to as Borderland) volcanic rocks studied previously. A comparison of ages of volcanic rocks occurring along the Borderland margin reveals an approximately age-progressive trend to the southeast. This represents an opposite sense to the apparent age-progressive trend for Miocene to Recent volcanic rocks north of the Western Transverse Ranges. Possible models to explain the compositions and age relationships of Miocene to Recent volcanic rocks of the Borderland region include southeasterly migration of volcanism in response to Rivera Triple Junction movement and slab window formation, or the presence of a weak “hotspot” that has been active since at least the Miocene. Identification of the process(es) responsible for Borderland volcanism is currently limited by dissection and northwestward movement of Borderland rocks in response to northwest–southeast shearing of the Pacific–North American plate boundary, and by the quality and quantity of reported age-dates and paleomagnetic information. The formation processes of volcanism in the Borderland have ramifications for palinspastic reconstruction of the margin, as well as for the thermal and magmatic evolution of western California in response to a change in plate motion in a subduction to transform setting. The Scripps Dike provides evidence that regions of the mantle beneath the California Continental Borderland were metasomatized by slab fluids in a manner similar to portions of mantle beneath central Baja California, Mexico.
Structure, Evolution, and Tectonic Significance of the Eastern Boundary of the Outer Continental Borderland
Authors: De Hoogh G.L. , Sorlien C.C. , Nicholson C. , Schindler C.S. , Francis R.D.
Published: May 2020

The Continental Borderland adjacent to southern California and northern Baja California is an exceptionally wide (240 km) region of ridges, islands, and bathymetric basins as deep as 2 km. This continental margin area includes the Nicolas terrane, a relatively intact outer terrane to the west characterized by the presence of Cretaceous and Paleogene forearc sedimentary rocks, and the adjacent Catalina terrane, a highly extended inner terrane to the east characterized by metamorphic basement rocks exhumed during early Miocene oblique rifting. To better understand this continental rifting process, we used regional grids of multichannel seismic reflection data, and stratigraphic information from industry wells and seafloor samples to investigate the nature and tectonic development of the boundary between the Outer Borderland forearc Nicolas terrane and the Inner Borderland denuded, exhumed Catalina terrane. These data show that this terrane boundary is largely defined by an angular unconformity that overlies and helps form an eastward termination or wedge-out of Outer Borderland forearc strata of earliest Miocene through Cretaceous age. These forearc sedimentary rocks were removed along the boundary primarily as a result of early-to-middle Miocene uplift and erosional truncation associated with exhumation of the Catalina basement. The boundary is not predominantly fault controlled. Along the northern part of the boundary, the East Santa Cruz Basin fault system, previously postulated to control the Nicolas–Catalina terrane boundary, is a predominantly east-dipping, Miocene oblique-normal fault system that has been reactivated with blind to partly blind oblique-reverse displacement. It does not align with the terrane boundary, and given its geometry, slip history, and the presence of Nicolas forearc sedimentary rocks on both sides of this fault system, it is unlikely to have had a major influence on terrane boundary development. South of San Nicolas Basin, there is no simple, through-going fault system, and where faults are present, they are often discontinuous segments that strike oblique to the boundary. This implies that major displacements associated with translation of the Outer Borderland were not localized to the eastern Outer Borderland boundary itself, but rather were likely distributed farther east within the evolving Inner Borderland rift.
Evolution of Pore Types and Petrophysical Properties Of Fault Rocks In Low‐Porosity Carbonates
Authors: Cilona A. , Solum J.G. , Lucca A. , Storti F. , Balsamo F. , Taberner C.
Published: May 2020

In carbonates, fault zone architecture, distribution of different types of fault rocks in fault cores (e.g., breccias, cataclasites), and the interplay between deformation and diagenesis must be considered to predict the flow properties of a fault zone. We present the results of an integrated structural and petrophysical study of two carbonate outcrops in central Italy, where faults are known to act as dynamic seals at depth, causing ≈70 m of hydraulic head drop in a karstified groundwater reservoir.

The architecture of these fault zones is very well exposed, allowing for detailed mapping of the along-strike and across-strike distribution and continuity of fault cores and associated fault rocks over a distance of ≈8 km. More than 150 samples, comprising several fault architectural elements and carbonate host rocks, were collected in transects orthogonal to the fault zones. Fault rock porosity and permeability were measured on 1-inch plugs and then linked to characteristic microstructures and fault rock textures. The results of this integration consisted of ranges of porosity and permeability for each type of fault rock.

A trend of increasing comminution and decreasing pore size is evident from the outer toward the inner portions of fault cores. Three types of breccias (crackle, mosaic, and chaotic) and various types of cataclasites were identified. Crackle breccias show the highest plug permeabilities (up to hundredss of mD), whereas the ultracataclasites have the lowest plug permeability (down to 0.01 mD, which is roughly equivalent to unfractured host rock). These data reveal the interplay between various fault rocks and host rock permeability and the development of permeability anisotropy of fault zones in carbonates.
A comparative analysis of methods for mapping groundwater pollution hazard: application to the Gallocanta Hydrogeologic Unit (Spain)
Authors: Orellana Macías José María , Perles Roselló María Jesús
Published: May 2020

Anthropogenic activities are the main sources of groundwater pollution. In order to prevent groundwater degradation and to apply suitable mitigation measures, hazard maps are a useful instrument for decision makers. The ultimate goal of the research is to analyse the effectiveness of several groundwater hazard indexes at the Gallocanta Lagoon Basin. To do so, the Hazard Index, the Danger of Contamination Index and the Pollutant Origin and its Surcharge Hydraulically method were applied and compare, and the potentialities and weaknesses of the resulting maps have been analysed. Accurate hazard maps were obtained and, based on their methodological approach, significant differences were found in relation to the rating process, the inventory of the sources, and the treatment of quantity and likelihood. In the light of the results, the indexes tended to undervalue the hazard level of agricultural activities, which were the main sources of pollution of the study area. Therefore, due to the characteristic land uses of the study area, typical of the Mediterranean context, some proposals to improve the indexes have been suggested.
Measles Outbreak Amplified in a Pediatric Ward: Lyantonde District, Uganda, August 2017
Authors: Biribawa Claire , Atuhairwe Joselyn Annet , Bulage Lilian , Okethwangu Denis Othuba , Kwesiga Benon , Ario Alex Riolexus , Zhu Bao-Ping
Published: May 2020

Background: Measles is a highly infectious viral disease. In August 2017, Lyantonde District, Uganda reported a measles outbreak to Uganda Ministry of Health. We investigated the outbreak to assess the scope, factors facilitating transmission, and recommend control measures.Methods: We defined a probable case as sudden onset of fever and generalized rash in a resident of Lyantonde, Lwengo, or Rakai Districts from 1 June-30 September 2017, plus ≥1 of the following: coryza, conjunctivitis, or cough. A confirmed case was a probable case with serum positivity of measles-specific IgM. We conducted a neighborhood- and age-matched case-control study to identified exposure factors, and used conditional logistic regression to analyze the data. We estimated vaccine effectiveness and vaccination coverage.Results: We identified 81 cases (75 probable, 6 confirmed); 4 patients (4.9%) died. In the case-control study, 47% of case-patients and 2.3% of controls were hospitalized at Lyantonde Hospital pediatric department for non-measles conditions 7-21 days before case-patient’s onset (ORadj=34, 95%CI: 5.1-225). Estimated vaccine effectiveness was 95% (95%CI: 75-99%) and vaccination coverage was 76% (95%CI: 68-82%). During the outbreak, an “isolation” ward was established inside the general pediatric ward where there was mixing of both measles and non-measles patients. Conclusions: This outbreak was amplified by nosocomial transmission and facilitated by low vaccination coverage. We recommended moving the isolation ward outside of the building, supplemental vaccination, and vaccinating pediatric patients during measles outbreaks.
Professional support during the postpartum period: Primiparous mothers’ views on professional services and their expectations, and barriers to utilizing professional help.
Authors: Nan Yiping , Zhang Jingjun , Nisar Anum , Huo Lanting , Yang Lei , Yin Juan , Wang Duolao , Rahman Atif , Gao Yan , Li Xiaomei
Published: May 2020

Background: Primiparous mothers who lack of experience and knowledge of child caring, are usually overwhelmed by multifarious stressors and challenges. Although professional support is needed for primiparas, there is a gap between the necessary high-quality services and the currently provided poor services. This study aimed to explore Chinese primiparous mothers’ views on professional services, identify barriers to utilizing professional support, and further understand mothers’ expectations of and preferences for the delivery of professional services.Method: A descriptive phenomenological study design was utilized in this study, and semi-structured interviews were conducted with 28 primiparous mothers who had given birth in the first year period before the interview and were selected from two community health centres in Xi’an city, Shaanxi Province, Northwest China. Each conversational interview lasted between 20 and 86 minutes. Colaizzi’s seven-step phenomenological approach was used to analyse the data.Results: Three major themes were identified: (a) dissatisfaction with current professional services for postpartum mothers, (b) likelihood of health care professional help-seeking behaviour, (c) highlighting the demands for new health care services. The related seven sub-themes included being disappointed with current hospital services; distrusting services provided by community health centres, private institutes and commercial online platforms; preferring not seeking help from professionals as their first choice; hesitating to express their inner discourse to professionals; following confinement requirement and family burden prevents mothers from seeking professional help; experiencing urgent needs for new baby-care-related services; and determining the importance of mothers’ needs. The necessity of professional support in the first month after childbirth was strongly emphasized by the participants. Online professional guidance and support were perceived as the best way to receive services in this study.Conclusion: The results of this descriptive phenomenological study suggested that the current maternal and child health care services were insufficient and could not meet primiparous mothers’ need. The results also indicated that identifying barriers and providing services focused on mothers’ needs may be an effective strategy to enhance primiparous mothers’ well-being, and further suggested that feasibility, convenience, and the cultural adaptability of health care services should be considered during the delivery of postpartum interventions.
Relationship between Internet addiction and sleep disturbance in high school students: a cross-sectional study
Authors: Tokiya Mikiko , Itani Osamu , Otsuka Yuichiro , Kaneita Yoshitaka
Published: May 2020

Background: The increase in the number of Internet users has increased Internet dependence worldwide. In adolescents, this dependence interferes with sleep, which is important for the development of psychophysiological capabilities. However, few large-scale surveys have descriptively examined the relationship between Internet addiction (IA) and sleep disturbance using standardized questionnaires. We conducted this study to determine the relationship between sleep disturbance in adolescents and IA based on the categories of the Young Diagnostic Questionnaire (YDQ) through a complete survey of one prefecture in Japan.Methods: In 2016, a self-report questionnaire was used to survey high school students (n=10,405, age range: 15–16 years) in all 54 day-boarding high schools in the selected prefecture. We defined “sleep disturbance” by scores greater than 5.5 points on the Japanese version of the Pittsburgh Sleep Quality Index. IA was evaluated using the YDQ: “IA,” when five of the eight YDQ items were present; “at-risk,” when three or four YDQ items were reported; and “non-IA,” when two or less YDQ items were positive. Multiple logistic regression analysis was undertaken with sleep disturbance as the dependent variable, IA as the explanatory variable, and adjustments for eight items.Results: High YDQ scores were associated with high prevalence rates of sleep disturbance in boys and girls. These findings persisted after controlling for other factors in the multiple regression model.Conclusions: Among Japanese adolescents, there was a significant independent relationship between IA and sleep disturbances.
Nursing and midwifery students’ experiences and perception of their clinical learning environment in Malawi: A mixed method study
Authors: Mbakaya Balwani Chingatichifwe , Kalembo Fatch Welcome , Zgambo Maggie , Konyani Alice , Lungu Florence , Tveit Bodil , Kaasen Anne , Simango Modesta , Bvumbwe Thokozani
Published: May 2020

Background The clinical learning environment is an important part of the nursing and midwifery training as it helps students to integrate theory into clinical practice. However, not all clinical learning environments foster positive learning. The aim of this study was to assess the experiences and perception of the clinical learning environment by nursing and midwifery students of in Malawi.Methods A mixed-methods approach was used to collect data from nursing and midwifery students. Quantitative data were collected using a Clinical Learning Environment Inventory, while focus group discussions were used to collect qualitative data. The interview guide had questions about clinical learning, supervision, assessment, communication and resources. The Clinical Learning Environment Inventory has six subscales of satisfaction, involvement, individualisation, innovation, task orientation and personalisation. Quantitative data were analysed by independent t-test and multivariate linear regression and qualitative data were thematically analysed. Results A total of 126 participants completed the questionnaire and 30 students participated in the focus group discussions. Satisfaction subscale had the highest mean score (M = 26.93, SD = 4.82) while individualisation had the lowest mean score (M = 18.01, SD =3.50). Multiple linear regression analysis showed a statistically significant association between satisfaction with clinical learning environment and personalization (β = 0.50, p = < 0.001), and task orientation (β =0.16 p= < 0.05). Teaching and learning resources, hostile environment, poor relationship with a qualified staff, absence of clinical supervisors, and lack of resources were some of the challenges faced by students in their clinical learning environment.Conclusion Although satisfaction with clinical learning environment had the highest scores, nursing and midwifery students encountered multifaceted challenges such as lack of resources, poor relationship with staff and a lack of support from clinical teachers that impacted negatively on their clinical learning experiences. Training institutions and hospitals need to work together to find a means of providing resources to students during clinical placement.
Factors associated with refractory autoimmune necrotizing myopathy with anti-signal recognition particle antibodies
Authors: Zhao Yawen , Zhang Wei , Liu Yilin , Wang Zhaoxia , Yuan Yun
Published: May 2020

Background: Autoimmune necrotizing myopathy with anti-signal recognition particle antibodies (ANM-SRP) is regarded as refractory myositis, whereby some patients respond poorly to conventional immunosuppression and require B cell depletion treatment. This study aimed to evaluate factors associated with refractory ANM-SRP.Results: Clinical and pathological data from 48 patients with ANM-SRP were collected. We followed up clinical symptoms and image changes over 12 months. Univariate and multivariate analyses were undertaken to determine the associations between variables of interest and poor response to therapy. Refractory ANM-SRP appeared in 32.5% of patients who showed no or minimal improvement after 12 months of steroid therapy. The clinical risk factors for refractory patients were being male (OR, 19.57; P<0.001), severe muscle weakness (OR, 7.51; P<0.001) and concurrent interstitial lung disease (OR, 39.70; P<0.001). The imaging refractory-related factor was the fatty infiltration rate of thigh muscles over 3 months (P=0.022) and the pathological factor associated with refractory ANM-SRP was the high expression of B cell activating factor receptor (BAFF-R) in muscle (P=0.036).Conclusion: Being male, severe muscle weakness, concurrent interstitial lung disease, quick development of muscle fatty infiltration and more BAFF-R and B lymphocyte infiltration in muscle indicate a poor response to immunosuppressive therapy in patients with ANM-SRP.
Correlation between bone turnover and metabolic markers with age and gender: a cross-sectional study of hospital information system data
Authors: Ju Shao , Zhou Shaosong , Qu Yuan , liang bibo , Yu Qing-Hong , Wu Jing
Published: May 2020

Background: Bone turnover and metabolic indicators are related to age and gender. Age and gender should be matched in subjects in disease control research of bone turnover and metabolism, but strict matching of gender and age increases the difficulty and cost of the research. Therefore, the aim of this study was to solve the question of whether it is necessary to strictly match age and gender in clinical research in bone metabolism.METHODS: Patient data were extracted from the HIS of ZhuJiang Hospital, Southern Medical University. From these data, a cross-sectional study was conducted. Data relating to seven bone turnover and metabolic indicators from 1036 patients between January 2018 and October 2019 were analyzed. A total of 156 patients aged under 20 were identified and analyzed separately. RESULTS: P1NP, β-CTx and 25(OH)D were significant different in individuals younger than 20 years of age. ALP was significantly higher in those under 20 years of age and lower at age 20-39 compared with other age groups. The concentrations of Ca and P were different among the groups aged 0-19, 20-39, and 40-59 years of age groups but exhibited no difference above 60 years of age. PTH expression was not dependent on age. P1NP, β-CTx and PTH concentrations were not significantly different between the genders within the same age group. ALP was significantly different between genders within the age range 20-59 years. Ca and 25(OH)D were significantly different between the genders for those older than 60. Serum P was significantly different in the two genders for those aged 40-79. CONCLUSION: P1NP and β-CTx were highly correlated with age. If these two indictors require analysis in a case control study, the patients and controls should be strictly matched by age under 20 years. The demarcation point for ALP was 40 years of age. Ca and P were strongly recommended strict matching according to age in disease research. The difference in P1NP, β-CTx, 25(OH)D and ALP between genders depends on age differences.
miR-454 suppresses the proliferation and invasion of ovarian cancer by targeting E2F6
Authors: An Yunhe , Zhang Jun , Tian Yanjie , Li Baoming , Cheng Xiaoyan , Zhang Xiaoli , Zhao Fangqi
Published: May 2020

Background The aberrant expression of microRNA-454 (miR-454) has been confirmed to be involved in the development of cancers. However, the functional role of miR-454 in the progression of ovarian cancer remains unclear. Methods The expression of miR-454 in ovarian cancer cells and serum of ovarian cancer patients was detected by RT-PCR. CCK8, colony formation, transwell, and flow cytometry assays were conducted to assess the effects of miR-454 on ovarian cancer cell proliferation, migration, invasion, and apoptosis, respectively. Dual-luciferase reporter assay was used to confirm the targeting relationship between miR-454 and E2F6. The expression pattern of E2F6 in ovarian cancer tissues was detected using immunohistochemistry (IHC) assay. The relative expression of related proteins was examined using western blot analysis. Results miR-454 was markedly down-regulated by hypoxia in ovarian cancer cells. Compared with normal samples, the expression of miR-454 was up-regulated in the serum of ovarian cancer patients, and correlated with the clinicopathological stages of ovarian cancer. Next, we found that miR-454 overexpression inhibited the proliferation, migration and invasion of OVCAR3 and SKOV3 cells, as well as promoted apoptosis. In addition, the Akt/mTOR and Wnt/β-catenin signaling pathway were inhibited by miR-454 in ovarian cancer cells. Mechanically, bioinformatic analysis and dual-luciferase reporter assay confirmed that E2F6 was a direct target of miR-454 and negatively regulated by miR-454 in ovarian cancer cells. Moreover, IHC analysis showed that E2F6 was highly expressed in ovarian cancer tissues. Finally, we found that the increasing cell proliferation and migration triggered by E2F6 overexpression were abolished by miR-454 overexpression. Conclusion Taken together, these results highlight the role of miR-454 as a tumor suppressor in ovarian cancer cells by targeting E2F6, indicating that miR-454 may be a potential diagnostic biomarker and therapeutic target for ovarian cancer.