bluuebunny/crossref_metadata_2025 huggingface dataset:
Histomorphological studies on the testicular capsule of crossbred Large White Yorkshire boars (Sus scrofa domesticus)
Authors: Abhin Raj K. P. , Sreeranjini A. R. , Maya S. , Vasudevan V. N. , Sunilkumar N. S.
Published: August 2022

The present study was conducted on the testes of six healthy adult Large White Yorkshire pigs. Parenchyma of testes of adult boars was surrounded by a thick fibrous testicular capsule composed of inner tunica vasculosa, middle tunica albuginea, and outer visceral layer of tunica vaginalis. Tunica vasculosa was prominent and characterised by loose connective tissue contained numerous blood vessels. Tunica albuginea was composed of irregular connective tissues madeup of collagen, elastin and reticular fibres. Visceral layer of tunica vaginalis was found as outer thin layer of testicular capsule comprised of mesothelium and connective tissue layer. Connective tissue layer was blended with underlying connective tissues of tunica albuginea.
Radiographic evaluation of hoof affections in dairy cattle
Authors: Anees R. , Dinesh P.T. , Nithin C. J. , Sooryadas S. , Chandy George , David P. Vinu
Published: August 2022

The study was undertaken to identify radiographic changes of hoof affections in dairy cattle. Out of the 78 cases radiographed, 67 cases were found to have lesions. Lateral and dorsopalmar/ plantar views of the affected foot of selected animals under study was evaluated.Soft tissue mass at inter-digital space, alterations in bone density of third phalanx, deviation of third phalanx were the major radiographic lesions diagnosed followed by fracture of third phalanx, osteomyelitis, deviation of second phalanx, periosteal reactions on phalanges and soft tissue swelling at coronary region. No radiographic changes were present in 14.10 per cent of the cases. Keywords: Radiography, hoof, dairy cattle
Study on personal profile of members in biodiversity management committees of Kerala
Authors: Chithra S. , Jiji R.S. , Senthilkumar R. , George Anu , Radhika G.
Published: August 2022

This is a study of the personal profile of members in Biodiversity Management Committees (BMCs), functioning under selected local self-governments of Kerala. BMCs constitute the grass root level institutional machinery for decentralized biodiversity governance. Five BMCs each from six districts, two each from the northern, central, and southern zones were selected purposively based on key informant technique. The selection of districts was based on criteria viz. indigenous cattle population, documentary evidence on native livestock of conservation value and expert guidance by subject matter specialists. Data regarding personal attributes of two hundred and forty members, eight each from thirty selected BMCs, procured through e-surveys and telephonic interviews were analyzed statistically. Results indicated dismal representation of women (37.08 per cent) as well as youth (21.25 per cent) in the committees. Another significant finding was the prevalence of political/ social workers among BMC members (61.66 per cent).The representation of stakeholder communities including those of farming, livestock and fisheries was minimal (17.08 per cent), whereas there was absolute absence of traditional knowledge holders and practitioners of indigenous medicine. Graduates and postgraduates together constituted nearly half of the respondents. All the members reported a working experience of five years in BMCs. The findings regarding training exposure in biodiversity management among BMC members revealed that a vast majority received not more than one training (79.58 per cent). Only a few had attended two or three training programmes (16.25 per cent).The Awards/recognitions received by individual members in biodiversity management was minimal (0.42 per cent), whereas at organizational level, 43.33 per cent of BMCs received only one and 3.33 per cent received more than one awards.
Household waste reduction efficiency of Hermetia illucens larvae
Authors: Rekha A. , Davis Justin , Mathew Joseph , Deepak Mathew D. K. , Chacko Binoj
Published: August 2022

Waste management with limited resource input under minimum space is the need of the hour. Black Soldier Fly (BSF)/Hermetia illucens is a fly prevailing and flourishing in our tropical climatic condition and is a miracle insect since it can solve a multitude of global problems like waste management, animal feed production and energy production. This fly is highly reputed in converting low quality biomasses in to high protein, high energy larvae meal. In this study we are assessing the quantity of BSF larvae produced from food waste and the waste reduction efficiency of the BSF larvae. Four kilograms of food waste was kept in a modified bin with 6 replicates and the development of the larvae was through natural breeding. The study revealed that from the above said quantity, an average of 0.567kg of BSF larvae can be produced per bin and average waste reduction efficiency was 73.81%.
Virulence determinants of Malassezia pachydermatis isolated from cases of canine dermatitis
Authors: Gagana H. S. , Davis K. Justin , Kumar K Vinod , Vijayakumar K.
Published: August 2022

Malassezia is a commensal organism known to cause disease under favourable conditions, and has been isolated from many animals as well as human beings. Malassezia pachydermatis is the most common cause of yeast dermatitis in dogs and there are many determinants involved in the production of disease in the host. This study aims to deterimine the presence of virulent determinants of the organisms isolated from fifteen dogs with dermatitis that may be involved in the pathogenic mechanism of Malassezia. The virulence determinants of M. pachydermatis viz; adherence, cellular surface hydrophobicity and biofilm formation were investigated. All the isolates studied were shown to produce all the virulent factors investigated in vitro which can be compared to the biological system. Adherence of organism on polystyrene plates was evident in all the isolates and the values ranged from 0.14 to 63 per cent with five isolates showing high adherence values. Hydrophobicity was variable and ranged from 1.78 to 69.46 per cent by two phase system with seven isolates showing moderate property. All the isolates were shown to produce biofilm by crystal violet staining technique and the optical density values ranged from 0.075 to 0.56 at 620 nm. No significant correlation was observed between the three virulent determinants examined. The presence of three virulent determinants investigated warrants their consideration in further studies for assessing the pathogenicity of Malassezia dermatitis in dogs.
Histological and ultrastructural characterisation as minimal criteria for assessing the success of the decellularisation protocols for tissue engineering applications
Authors: Megha K. G. , Balakrishnan Nair Dhanush Krishna , Divya C. , Sajitha I. S. , Vasudevan V. N. , Umashankar P. R. , Devi S.S.
Published: August 2022

There is a great demand of suitable biomaterials for tissue engineering applications in regenerative medicine. Decellularized extracellular matrix scaffolds derived from different organs and tissues have been successfully applied for human use as therapeutic agents in many tissue defects. The aim of the present study was to establish histological and ultrastructural characterisation as minimal criteria for assessing the suitability of decellularised bioscaffolds in tissue engineering applications. The study was performed on bovine omentum processed by a natural bovine bile based decellularisation protocol. Histological analysis and scanning electron microscopy examinations were performed and compared with an established decellularised bovine pericardial scaffold. Gross examination revealed that the decellularisation process did not alter the shape of the omentum. Histological examination confirmed the preservation of the collagenous fibres without any observable cell nuclei following decellularisation. Further, scanning electron microscopy examination demonstrated the arrangement and ultrastructure of collagen fibrils in the bioscaffolds. Our results suggest that histological and ultrastructural characterisation provide preliminary data on determining the biocompatibility of scaffolds before planning in vivo studies in tissue engineering applications.
Organoleptic evaluation of Ladakhi churpe enriched with apricot and spinach
Authors: Hussain Anwar , Yangchan Jigmet , Tundup Phuntsog , Spaldon Sonam , Dolkar Disket
Published: August 2022

Dried dairy products viz. churpe-balls and churpe-strips were developed with the incorporation of apricot powder into cottage cheese at different levels (05, 10, 15 and 20%) and spinach powder at levels 03, 06, 09 and 12 percent, respectively. The sensory attributes of the products were studied during the investigation. The appearance of balls first decreased, then increased and again decreased and that of strips first increased and then decreased. The supplementation resulted in significant (P < 0.05) decline in texture of both products. Flavor increased in balls and decreased in strips with the addition of supplements. Overall acceptability first got increased and then decreased with the increase in the level of supplementation of the products. The titratable acidity increased whereas pH decreased in both products upon the incorporation of additives. Storage studies done for 360 days reveal that except texture and titratable acidity, there were losses in all the parameters in both products with the advancement of storage. Except flavor in case of balls and overall acceptability and pH in case of strips, all the interaction effects of supplementation and storage were found to be statistically significant.
Resource use efficiency of milk production among different types of dairy farms in Kerala
Authors: George Sabin , Saseendran P. C. , Anil K. S. , Gleeja V. L. , Benjamin E. D. , Muhammad Aslam M. K. , Pramod S.
Published: August 2022

The present study analysed the resource use efficiency of milk production among different types of dairy farms in Kerala. The area of study and the respondents were selected using a stratified multi-stage random sampling technique. The farmers/farm households were categorized into small farms (1-2 cows), medium (3-10 cows), and large farms (more than ten cows). The relationship between inputs and milk production has been explored through the production function approach. Resource use efficiency was essentially a comparison between the Marginal Value Product (MVP) of an input with its price that gave direction on the use of that particular input in order to maximize profit. The results showed that in small farms, the MVPs of two inputs viz. roughages and labour was significantly less than unity, signifying overutilisation of these inputs. The MVP value of concentrate was significantly higher than unity, indicating their underutilisation in the milk production process. The MVP of concentrate was positive and significantly greater than unity in medium and large farms, also indicating their underutilisation.
Antibiofilm activity of berberine and capsaicin in combination with quinolones against Staphylococcus aureus from bovine mastitis
Authors: Mohan Arya , Nisha A. R. , Sujith S. , Suja Rani S. , Thomas Naicy
Published: August 2022

Antimicrobial resistance which causes failure of antibiotic therapy has become a serious global issue nowadays. Bacteria develop resistance towards an antibacterial agent via many mechanisms. Biofilm formation by bacteria poses severe threat to the treatment of infections. The combination of plant molecules with antibiotics can combat antimicrobial resistance. In the present study, antibiofilm activity of two plant molecules berberine and capsaicin was investigated against Staphylococcus aureus isolates from bovine mastitis cases. Antibiotic sensitivity testing revealed that berberine and capsaicin when combined with quinolones increased the diameter of zone of inhibition in a dose dependent manner. In vitro biofilm assay using congo red agar plate method revealed the antibiofilm activity of berberine and capsaicin in combination with quinolone antibiotics. The study concludes that the combination of phytoconstituents with antibiotics can alleviate resistance mechanisms in bacteria.
Phytochemical analysis and biosynthesis of silver nanoparticles from aqueous extract of seeds of Sesamum indicum
Authors: Keerthika V. , Nisha A. R. , Nair Suresh N , John Preethy , Ramnath V.
Published: August 2022

Plants have been in use in medicine from time immemorial. Sesamum indicum, an ancient seed crop, has been widely used mainly for its oil. It is regarded as highly beneficial for its nutritive value and therapeutic effect. It is known to have anti-allergic, anti-inflammatory, anticancer, analgesic and many other pharmacological activities. In this study, seeds of S. indicum were subjected to aqueous extraction followed by evaluation for the presence of phytochemical constituents. The aqueous extract of seeds of S. indicum after phytochemical testing, was found to contain alkaloids, phenols, steroids, flavonoids, diterpenes, glycosides and tannins. Following this, silver nanoparticles were biosynthesised from the extract, where the phytochemicals acted as reducing and capping agents for the nanoparticles formed. The synthesised nanoparticles were characterised by using UV-visible spectroscopy, energy dispersive X-ray spectroscopy, field emission scanning electron microscopy and X-ray diffraction. The synthesis of nanoparticles from plant extract is gaining importance now-a-days owing to the effectual activity elicited by them when compared to activity of plant compounds alone.
Molecular characterisation of virulence genes in Staphylococcus aureus associated with clinical bovine mastitis
Authors: Easaw Anugraha Mercy , Vijayakumar K. , Davis K. Justin , Shyma V. H. , Surya S.
Published: August 2022

Staphylococcus aureus is the most frequently isolated pathogen from bovine mastitis including subclinical, clinical, and chronic infections. Virulence factors possessed by S. aureus aid in causing infection and inflammation by producing toxins and proteins, which are responsible for the pathogenesis of the disease. In the current study out of 51 animals presented with clinical mastitis, S. aureus was isolated from the milk of 18 animals. S. aureus was confirmed by genus and species level identification using polymerase chain reaction. Molecular characterization of selected virulence genes including thermonuclease (nuc) and Panton Valentine Leucocidin (PVL) was performed in all the S. aureus isolates. Presence of nuc gene was observed in all the isolates (100 %) of S. aureus. No isolates were found to be positive for the presence of PVL gene. Profiling the virulence genes is an important tool for epidemiological studies of mastitis, which can be employed for the prevention and control of the disease.
Effect of supplementation of biotin in total mixed ration of dairy cows on rumen fermentation characteristics by in vitro gas production technique
Authors: Rani K. Jasmine , Dildeep V. , Ally K. , Syam Mohan K. M. , Aravindakshan T. V. , Anil K. S.
Published: August 2022

An experiment was conducted to assess the effect of supplementation of biotin on rumen fermentation parameters and microbial biomass production by in vitro gas production technique. Biotin was supplemented to the substrate - total mixed ration (TMR) at various doses viz., T1-0 (control), T2-0.5, T3-1.0, T4-1.5 and T5-2.0 mg/kg DM. The in vitro true dry matter degradability, total gas production, metabolizable energy and microbial protein production were found be increased proportionally to the dose of biotin. However, the methane and volatile fatty acid production were not affected by biotin supplementation. Results revealed that the positive effects on in vitro ruminal fermentation were dose-dependent and biotin can be incorporated in the diet of dairy cows to improve nutrient digestibility and rumen biomass production.
Carcass characteristics and proximate composition of Mithun (Bos frontalis) carcass
Authors: Mondal S. K. , Das K. S. , Roy S. K. , Rajkhowa C.
Published: August 2022

In order to study the carcass characteristics, six mithun (Bos frontalis) of either sex were slaughtered and their body tissues were analysed for proximate principles in the present investigation. The physical carcass characteristics like the carcass length, weight, dressing percentage etc. were also determined. The data analysis revealed that the mean carcass length and weight were measured as 162.10±6.15 cm and 242.25±36.75 kg, respectively. The overall dressing percentage was found to be 60.65±1.68% in mithun, while the subcutaneous fat thickness was recorded to be 42.15±2.15 mm. The heaviest organ of the mithun carcass was observed to be the stomach (68.2±0.1 kg), the lightest was recorded to be the pancreas (0.45±0.10 kg). The nutrient composition of mithun meat was excellent with protein content of 18.74±1.25% and fat content of 0.48±0.03%. This study further recommended the need of a detailed study on the effect of mithun meat consumption on human health in future.
القياس المصلحي: دليل فقهي اعتبره الشرع
Authors: Al-Khal Samir
Published: August 2022

تسعى هذه الدراسة إلى مناقشة التوجه العام لأغلب الدراسات الأصولية التراثية في ارتباطها بقضايا العلة، من حيث انحصار مباحثها في الوصف الظاهر المنضبط، وإغفال شقها الثاني في علاقته بالحكمة ذات البعد المصلحي. تتبع الدراسة المنهج التحليلي الوصفي والذي قد أسفر عن فك الحدود الحادثة بين الدرس الأصولي والمقاصدي، من خلال إبراز صحة التعليل بالحكمة، والقياس بناء على المصلحة ذاتها، بغية فتح آفاق اجتهادية أكثر وأوسع للفقه الإسلامي، من أجل إيجاد حلول شرعية لما يلفظه الواقع الفردي والجماعي من وقائع متعددة ومعقدة في الوقت ذاته.
AN EXAMINATION OF FISCAL DECENTRALIZATION IN KAZAKHSTAN
Authors: AMAGOH Francis
Published: August 2022

Fiscal decentralization is said to offer a number of benefits for public sector governance, including economic growth, accountability, and responsiveness of government officials to local demands and needs. Increased autonomy over revenues and expenditures through separation of control over different tax bases between the central and regional government has the potential to promote the efficiency and accountability of local governance. Kazakhstan, been a unitary state has all revenues collection and allocation decisions made by the central government. Allocations to the regions are made based on certain criteria, such as size, demography, importance of the region to the national economy, etc. This means that regional and local governments have little incentives to devise means that would generate internal revenues. This can give local officials a convenient scapegoat for their shortcomings in providing public services, as they could easily pass the blame to the central government. The aim of this paper is to examine how granting more accountability and revenue-generating authority to Kazakhstan’s regions would improve public service delivery, and have an aggregate macroeconomic performance and growth for the country as a whole. The methodology is based on the use of secondary sources (such as government reports, policy documents, etc.). The paper contributes to the body of knowledge by cautioning that fiscal decentralization without accountability to the local populace limits the benefit of responsiveness to local needs, while highlighting the importance of local fiscal autonomy on fiscal performance, amongst others.
Fresh product e-tailer’s optimal fresh-keeping strategy under three scenarios
Authors: Huang Qiufang , Hu Yaqin ,   School of Management, University of Science and Technology of China, Hefei 230026, China
Published: August 2022

In the direct sales model, the e-tailers sell fresh products to consumers in the online market and promise consumers a full-refund policy without return. Consumers are always concerned the products’ freshness level before purchasing online fresh products. Third-party logistics (3PL) providers will be motivated to exert a fresh-keeping effort to keep the fresh product at the optimum level when offering consumers or e-tailers fresh-keeping services. Considering the fresh-keeping service provided by 3PL providers, to alleviate consumers’ concerns about the freshness level and encourage them to purchase fresh products, some e-tailers will purchase fresh-keeping services from 3PL providers and offer them to consumers for free. However, some e-tailers have stopped offering the free service; they have offered consumers the opportunity to purchase fresh-keeping services. To explore an e-tailer’s optimal fresh-keeping strategy, we consider a market consisting of an e-tailer and a 3PL provider. Three alternative scenarios are discussed, scenario N: no fresh-keeping service; scenario C: some consumers voluntarily purchase fresh-keeping services; and scenario S: the e-tailer offers a complementary fresh-keeping service. We find that introducing a fresh-keeping service increases the retail price in scenario C when the coefficient of fresh-keeping cost is high and the unit fresh-keeping service fee is low, but that decreases in scenario S when the unit fresh-keeping service fee is low. Comparing the e-tailer’s equilibrium profits, we find that introducing a fresh-keeping service does not necessarily benefit the e-tailer. The coefficients of fresh-keeping costs and unit fresh-keeping service fees play a critical role in selecting the fresh-keeping strategy. Meanwhile, the 3PL provider is biased; specifically, the 3PL provider’s fresh-keeping effort is related to that of the policyholder.
Pengaruh Kepemimpinan Kepala Madrasah Dan Kompetensi Guru Terhadap Kinerja Guru Madrasah Tsanawiyah Darunnajah Kecamatan Cilawu Kabupaten Garut
Authors: Jaelani Ahmad
Published: August 2022

Tujuan penulisan artikel ini adalah untuk mengetahui pengaruh kepemimpinan kepala madrasah dan kompetensi guru terhadap kinerja guru MTs Darunnajah Kecamatan Cilawu Kabupaten Garut. Metode penelitian yang digunakan dalam penelitian ini adalah metode deskriptif analisis dengan teknik survey, wawancara, observasi dan studi dukumentasi. Sedangkan teknik analisis data yang digunakan untuk menjawab hipotesis penelitian ini adalah statistik dengan model analisis jalur (path analysis). Adapun populasi dan sekaligus menjadi responden dalam penelitian ini adalah seluruh guru mata pelajaran MTs. Darunnajah Kecamatan Cilawu Kabupaten Garut sebanyak 42 orang, karena tidak dilakukan pengambilan sampel. Hasil pengujian hipotesis utama dalam penelitian ini dapat disimpulkan bahwa kepemimpinan kepala madrasah (X1) dan kompetensi guru (X2) berpengaruh positif dan signifikan terhadap kinerja guru (Y). Artikel ini memiliki kesimpulan bahwa untuk meningkatkan kinerja guru secara maksimal dapat dilakukan dengan meningkatkan kompetensi guru dan melaksanakan fungsi kepemimpinan kepala madrasah dengan optimal.
Manajemen Kelas Dalam Meningkatkan Proses Pembelajaran Di Madrasah
Authors: Hidayat Wahyu , Jahari Jaja , Nurul Shyfa Chika
Published: August 2022

Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan manajemen kelas dalam meningkatkan proses pembelajaran di madrasah (penelitian di MTs Informatika Mifthaul Huda Bandung). Metode yang digunakan dalam penelitian ini adalah metode deskriptif – kualitatif. Teknik yang digunakan dalam pengumpulan data adalah observasi, wawancara dan studi dokumentasi. Analisis data dilakukan dengan reduksi data dan penyajian data. Di MTs Informatika Miftahul Huda Bandung, peneliti menemukan bahwa guru dan manajer kelas memiliki peran utama didalamnya untuk mewujudkan kelas yang efektif. Berdasarkan hasil penelitian, manajemen kelas dalam meningkatkan proses pembelajaran di MTs Informatika Miftahul Huda Bandung, yaitu: (1) latar alamiah MTs Informatika Miftahul Huda Bandung, (2) perencanaan manajemen kelas, (3) pelaksanaan manajemen kelas, (4) evaluasi manajemen kelas, (5) usaha peningkatan proses pembelajaran, (6) faktor penunjang dan penghambat manajemen kelas dalam meningkatkan proses pembelajaran, dan (7) hasil manajemen kelas dalam meningkatkan proses pembelajaran di MTs Informatika Miftahul Huda Bandung.

Kata kunci : Pendidikan, Kelas, Pembelajaran
AMELOBLASTOMA CONVENCIONAL: RELATO DE CASO CLÍNICO
Authors: Alves Nara Cybele Gomes , Lopes Liana Falcão , Miura Mavylla Carvalho , Fernandes Victoria Maria Custódio , Freire Filho Francisco Wagner Vasconcelos
Published: August 2022

Introdução: O ameloblastoma é uma neoplasia benigna de origem epitelial odontogênica, que possui crescimento lento, porém bastante agressivo, com altas taxas de recidiva. Pode causar grandes mutilações após os tratamentos, tendo assim maiores implicações clínicas. É dividido atualmente em três tipos, o convencional, o unicístico e o periférico. Sendo o convencional o mais frequente entre eles, chegando a 86% dos casos. Objetivo: Relatar um caso clínico de ameloblastoma convencional tratado por ressecção cirúrgica que apresentou recidiva após 2 anos. Métodos: Relato de acompanhamento de 4 anos do caso clínico. Resultados e Discussão: Paciente F.N.C., sexo masculino, 32 anos, normossistêmico, compareceu ao atendimento em 2019 com a queixa principal “inchaço na mandíbula”. No exame clínico, observou-se um aumento de volume na região de corpo e ramo da mandíbula do lado esquerdo, com sintomatologia dolorosa e tempo de evolução de 5 anos. No exame radiográfico, observou-se extensa lesão radiolúcida, multiloculada, com margens festonadas e aspecto de bolha de sabão, com expansão da cortical basilar e alveolar. Em 2020 foi realizado tratamento por meio de ressecção cirúrgica em bloco com remoção do corpo e ramo mandibular do lado esquerdo com margem de segurança e instalação de uma placa de reconstrução de titânio articulando o côndilo mandibular esquerdo e a região da protuberância mentual. Durante acompanhamento de 2 anos pós-cirúrgico apresentou em exame radiográfico lesão radiolúcida multiloculada semelhante a aspecto de recidiva do ameloblastoma. Conclusões: A escolha do tratamento do ameloblastoma ainda é controversa, e mostra a necessidade em elucidar melhor sobre os fatores responsáveis pela patogênese dessa lesão. Diante disso, é muito importante analisar detalhadamente cada caso. Porém, apesar do tratamento radical consistir em uma cirurgia muito mutiladora, muitos estudos comprovam que a ressecção em bloco com osteotomia periférica com margem de segurança diminui a taxa de recorrência.
L-PRF COMO ADJUVANTE NO TRATAMENTO DE OSTEONECROSE
Authors: Pinheiro Pedro Augusto Lopes , Melo Harysson Costa , Barreto Raíssa Soares , Vieira Luiz Victor Marques , Albuquerque Assis Filipe Medeiros
Published: August 2022

INTRODUÇÃO: A osteonecrose dos maxilares associada ao uso de drogas anti-reabsortivas, é uma séria complicação caracterizada pela presença de osso necrótico exposto na região maxilofacial, de difícil manejo pelo profissional. A mandíbula apresenta maior acometimento, devido a sua menor vascularização, quando comparada à maxila. Sob esse viés, uma proposta alternativa de tratamento que vem apresentando bons resultados em pesquisas recentes é a Fibrina Rica em Plaquetas e Leucócitos (L-PRF). OBJETIVO: O objetivo do presente trabalho é revisar a literatura a fim de avaliar a efetividade do uso do L-PRF como adjuvante no tratamento da osteonecrose, bem como mostrar seus potenciais benefícios. MÉTODOS: Para a elaboração do presente trabalho, foi realizada uma busca na base de dados “Pubmed” utilizados as palavras chaves “l-prf”; “osteonecrose”; “odontologia”. A pesquisa resultou em 12 artigos, onde destes 6 artigos foram selecionados após a leitura crítica de títulos e resumos. Foram incluídos três relatos de caso e três revisões de literatura. CONCLUSÃO: Após a leitura dos artigos foi observado que o tratamento cirúrgico com o uso de Fibrina Rica em Plaquetas e Leucócitos possibilita uma recuperação menos dolorosa e desconfortável ao paciente, entretanto ainda são necessários novos estudos para fomentar a consolidação da técnica para tratamento da osteonecrose dos maxilares.
PROJETO GAPE COMO AUXÍLIO NO TRATAMENTO E NA REABILITAÇÃO DE PACIENTES ONCOLÓGICOS SUBMETIDOS À RADIOTERAPIA DE CABEÇA E DE PESCOÇO: UM RELATO DE EXPERIÊNCIA DE 6 ANOS
Authors: Felix Giselle Araujo , De Carvalho Anny Caroliny Moraes , Vieira Luiz Victor Marques , Albuquerque Assis Filipe Medeiros
Published: August 2022

Introdução: A radioterapia é uma forma de tratamento antineoplásico servindo de forma curativa ou paliativa para melhorar a qualidade de vida do paciente oncológico, buscando erradicar a lesão por meio do uso controlado de radiação, podendo ser feito de forma isolada ou em associação à quimioterapia e/ou à cirurgia. Diante disso, os pacientes oncológicos tratados com a radioterapia são constantemente susceptíveis a vários efeitos secundários que incluem principalmente xerostomia, mucosite e osteorradionecrose. Para evitar isso, o tratamento odontológico deve ser realizado de forma preventiva, a fim de eliminar e de estabilizar as condições que desencadeiem possíveis infecções locais e/ou sistêmicas. Objetivo: O objetivo do presente trabalho é descrever um relato de experiência de 6 anos do projeto GAPE (Grupo de Atendimento a Pacientes Especiais), acerca do tratamento odontológico dos pacientes oncológicos submetidos à radioterapia. Relato de experiência: O grupo de atendimento a pacientes com necessidades especiais (GAPE), criado no ano de 2016, possui seus atendimentos realizados na Clínica Odontológica da Unifor, com atendimento médio de 130 pacientes/ano. Dentre esses, cerca de 40% apresentam neoplasia e fazem tratamento com radioterapia. Para o tratamento de adequação bucal desses pacientes, além do tratamento odontológico realizado, manobras específicas são utilizadas com a finalidade de minimizar e de melhorar as condições que, potencialmente, podem prejudicar o paciente, como as mucosites, a osteorradionecrose e as infecções secundárias. Para isso, tratamentos com o uso da laserterapia de baixa intensidade, o uso de saliva artificial e o uso do PRF (plasma rico em fibrina) são tratamentos comumente realizados com a finalidade de melhorar tais questões, dando assim, uma melhor qualidade de vida aos pacientes durante e após o seu tratamento. Conclusão: Os pacientes oncológicos, requerem uma série de cuidados especializados para melhorar a condição bucal e favorecer o tratamento. Os cuidados odontológicos são de suma importância pois favorecem uma melhor qualidade de vida aos pacientes durante o tratamento. Além disso, esses métodos de tratamento adicionais são importantes para evitar e tratar as principais condições oriundas da radioterapia e da neoplasia presente.
Pharmacokinetics of ibuprofen: comparison of the fixed combination of ibuprofen plus caffeine with ibuprofen lysinate or ibuprofen acid. Results of two single-dose studies (randomised, single centre, crossover, open-label)
Authors: Weiser Thomas
Published: August 2022

Analgesics containing readily soluble ibuprofen (e.g. as the lysinate) were developed with the aim of ensuring a more rapid relief of pain than ibuprofen acid through faster absorption in the gastrointestinal tract. Since the degree of gastric filling can have a significant influence on absorption, two studies investigated the pharmacokinetics of ibuprofen lysinate and ibuprofen acid (combined with caffeine) on an empty (fasted) stomach and after a standard breakfast. The absorption of ibuprofen as the lysinate was only faster when taken on an empty stomach; after a standard breakfast, the time to peak plasma levels with ibuprofen acid (with caffeine) was actually shorter than for ibuprofen lysinate. Since analgesics are usually not taken on an empty stomach, this reduces the alleged advantages of ibuprofen lysinate.
Sacroiliac luxations in cats: Surgery or conservative treatment?
Authors: Yurtal Ziya , Altuğ Muhammed Enes , İşler Cafer Tayer , Deveci Mehmet Zeki Yılmaz , Alakuş İbrahim , Kırgız Ömer , Alakuş Halil , Kaya Ufuk
Published: August 2022

Sacroiliac luxations constitute an important part of hip fractures. In the treatment phase, a choice should be made between surgical and conservative treatment. Which treatment option will yield more effective results depends on many variable factors. In the present study, some of these factors were mentioned and their effects on treatment and outcomes were evaluated. A total of 61 cats, 26 female and 35 male, of various breeds and ages, were included in the study. The mean age of the cats included in the study was 16 months. The mean weight of the cats was 2.87 kg. Cases were categorized as ages, ≤6, 7-12, and ≥13 months of age. In addition, the success criteria of etiological causes, luxation type, and concomitant traumas on decision and outcomes were evaluated. Conservative treatment was preferred more in all age groups and success rates were higher than those of surgery. Conservative treatment was preferred in both genders, and the recovery rate was higher in males than that in females. Regardless of the cause of the trauma, more conservative treatment was preferred, and the rate of good recovery was higher in high-rise falls. Even if there was traumatic injury in addition to sacroiliac luxation, conservative treatment was preferred and the rate of good recovery was higher in cases without concomitant traumatic injury. As a result; age, gender, luxation type and concomitant traumatic injury were not statistically significant on treatment choice. However, good recovery was statistically significant in cases without concomitant traumatic injury.
具有雙重功能之強制抽血──評憲法法庭111年憲判字第1號判決
Authors: 林明鏘 林明鏘
Published: August 2022

」
肇事駕駛人強制受檢法制的體系解釋與憲法審查──憲法法庭111年憲判字第1號判決淺釋
Authors: 李建良 李建良
Published: August 2022

」
The role of non-HDL cholesterol and atherogenic indices in predicting poor glycemic control among type 2 diabetic patients in Basrah, Iraq
Authors: Al-Asadi Jasim N , Al-Naama Lamia M
Published: August 2022

Background: Dyslipidaemia is frequently associated with type 2 diabetes mellitus and it is the major contributor to cardiovascular diseases among type 2 diabetic patients. Despite the fact that several researches have proven the association between glycemic control and dylipidemia in type 2 diabetic patients, the results are rather varied.

Objectives: The aim of the study is to investigate the clinical relevance of lipid profile as predictive biochemical model for glycemic control in type 2 diabetic patients.

Methods: A cross-sectional study including 329 type 2 diabetic patients was done in Al-Sadr Teaching Hospital, Basrah, Iraq. Brief history, clinical examination, and investigations including fasting plasma glucose, lipid profile, and glycosylated hemoglobin were done. HbA1c >7% was considered as poor glycemic control. Receiver operator characteristics (ROC) analysis and logistic regression analysis were used to evaluate the association between lipid profile and HbA1c level.

Results: Out of 329 diabetic patients, 278 (84.5%) showed poor glycemic control. The univariate analysis showed a significant association between lipid parameters and poor glycemic control. ROC and logistic regression analyses found that TC/HDL (OR: 4.94; 95% CI: 2.35–10.41; P < 0.001) and LDL/HDL (OR: 4.63; 95% CI: 1.96–10.98; P < 0.001) were the only significant independent predictors of glycemic control, while non-HDL cholesterol was a weak predictor of glycemic control despite its significant association (P = 0.02).

Conclusion: LDL/HDL and TC/HDL ratios reveal promising indicators for predicting glycemic control in type 2 diabetic patients.
Gemcitabine and cisplatin in inoperable, loco-regionally advanced and metastatic gallbladder cancer: A study from Northern India cancer institute
Authors: Talwar Vineet , Raina Shubhra , Goel Varun , C. Doval Dinesh
Published: August 2022

Aims: The primary objective of this study was to determine the response rates of the gemcitabine and cisplatin combination chemotherapy in treatment naive patients with inoperable gall bladder cancer. The secondary objectives were to evaluate the toxicity, progression free survival (PFS), and overall survival.
Materials and Methods: Treatment naive patients with histologically proven inoperable gallbladder cancer treated with gemcitabine and cisplatin chemotherapy between March 2010 and December 2014 were included in this retrospective study. The dose of gemcitabine and cisplatin was 1 g/m2 on day 1 and 8, and 75 mg/m2 on day 1, in a 21-day cycle respectively. Computed tomography scan was used for response assessment.
Results: There were 32 men and 59 women with a median age of 52 years (range 30–67 years). Of the 91 patients, 9 (9.9%) patients achieved a complete response and 41 (45.1%) patients achieved a partial response for an overall response rate of 55%. The median number of chemotherapy cycles administered were 6 (range 1–9). The median progression free survival (PFS) was 5.4 months [95% confidence interval (CI) 3.9–7.9 months], with one year survival rate of 34.1%. Common toxicity criteria grade 3 or 4 anemia was seen in 4 (4.4%) and 2 (2.2%) patients respectively. Grade 3 neutropenia and thrombocytopenia was observed in 10 (10.9%) and 9 (9.9%) patients respectively.
Conclusion: The combination of gemcitabine and cisplatin is active in advanced gallbladder carcinoma with mild toxicity.
Russian South Asia Policy: From Estrangement to Pragmatism
Authors: Almas Haider Naqvi  , Assistant Professor Dr. Syed Qandil Abbas
Published: August 2022

This paper is an attempt to analyse the Soviet and Post-Soviet Russian policy responses towards the South Asia particularly India and Pakistan contextualising how the systemic pressures stimulated from balance of power and intervened by domestic factors specifically ideology and leaders’ images played important role in policy formulation and execution. Majority explanations of Soviet-Russian South Asian policy do not offer analysis of inside-out interactions. Incorporation of domestic factors in analysis would provide better explanation of Soviet-Russian policy and the key developments in South Asia. Soft-positivist methodology with qualitative and quantitative methods are employed to analyse data from primary and secondary sources. The paper categorises four distinct phases of Russian South Asia policy responses; Estrangement (1947-1953), Engagement (1954-1971), Indo-Centrality (1971-1991), Pragmatism (1991-2022) stimulated by systemic and intervened by domestic factors. Balancing and competition with the United States (US) and China primarily motivates Soviet Union to shape policy but ideology, leaders’ perceptions and images also influenced.
COVID-19 in Iran
Authors: Boushehri Elham , Abedini Samireh , Yousefi Pooneh , Hassaniazad Mehdi , Aghamolaei Teamur
Published: August 2022

Background: Today, people all over the world are suffering from COVID-19 pandemic. Certainly, exploring the characteristics of the corona virus and making an effective vaccine are important efforts in preventing and controlling the disease. At the same time, it is necessary to conduct studies to identify high-risk groups and protect them against disease. Method: This study's research population was 281 people with fever, coughing, and respiratory disorder admitted to an educational hospital affiliated with the Hormozgan University of Medical Sciences in the south of Iran. If RT-PCR test was positive, the patients were considered infected. Infected patients were hospitalized if they had impaired respiratory function. The main kinds of lifestyle information collected from patients were: physical activity data, emotional or spiritual status, tobacco/opium/alcohol use status, sleep, and nutritional data, comorbidity disease data. Multivariable OR (95% CI) regression tests were applied to detect the relation between some important lifestyle variables with the probability of infection by coronaviruses and hospitalization due to respiratory disorder findings. Results: it was identified that 22 from 28 covariates had significant associations with the risk of infection and hospitalization.
A case report of a heart mass
Authors: Moghadam Manijeh Yousefi , Namdar Reza Beheshti , Zadeh Hamid Movahed , Rahimi Zahra , Ghodsi Majid
Published: August 2022

Introduction: Certain cardiac tumors are asymptomatic and are detected by chance after autopsy. The clinical signs and symptoms of cardiac tumors vary greatly and are determined mainly by the tumor's location and size rather than its histology. Cardiac masses have a broad differential diagnosis, and it is critical to differentiate between neoplastic and non-neoplastic cardiac masses and benign and malignant neoplasms. Surgery is advised in situations of heart failure symptoms, treatment-resistant ventricular arrhythmias, or blockage of the heart's inlet or outlet pathways. Presentation: In this research, a 60-year-old man presented to the hospital with complaints of shortness of breath, and after an echocardiogram and CT scan, he was diagnosed with a right atrial tumor, which required surgery. Conclusion: The patient was sent to the oncology unit for additional treatment after surgery, excision of the mass, and analysis of the pathology sample.
Synthesis, preliminary anticonvulsant and toxicity screening of substituted 3-(Dimethyl/Diethylamino)-{1-[4-methyl-2-substitutedphenyl-2,5-dihydro-1,5-benzothiazepin-3-yl]}propan-1-one
Authors: Chaudhari V. K. , Pathak D. , Hussain Z.
Published: August 2022

Background; 1,5-benzothiazepine moiety is a very important pharmacophore bioactive compound that exhibits different biological activities. By the literature review the basic structure requirements for anticonvulsant activity contains molecular weight less than 500, Oil/water distribution coefficient is less than 5, Hydrogen bond donors more than 5 and Hydrogen bond acceptor more than 10. Aim of study: Aim of the study is to synthesize a novel series of 1,5-benzothiazepine nucleus containing Mannich bases which retained anticonvulsant biological activities with less toxic effect. Materials & methods: We synthesized successfully various substituted 3-(Dimethyl/Diethylamino)-{1-[4-Methyl-2 substitutedphenyl-2,5-dihydro-1,5 benzothiazepin-3-yl]}propan-1-one (6a-6t). Completion of chemical reaction was monitored by thin layer chromatography on silica gel G coated plates and final compounds were purified by recrystallisation with methanol. The chemical structure of synthesized compounds confirmed by chromatographi, electro analytical and physiochemical analysis. Results & discussion: All the novel synthesized compounds screened by anticonvulsant activity by maximum electroshock induced seizure against Phenytoin as standard. All the synthesized compounds showed significant anticonvulsant activity. The most potent significant compound was found 3-(Dimethylamino)-{1-[3-chlorophenyl-4-methyl-2, 5-dihydro-1,5-benzothiazepin-3-yl]}propan-1-one (6e). Further, preliminary safety profile of most potent significant compound 6e was evaluated by acute oral toxicity and neurotoxicity testing.
Antifungal activity of eugenol and clove leaf essential oil (Syzygium aromaticum L.) against clinical isolates of candida species
Authors: Murtiastutik Dwi , Citrashanty Irmadita , Endraswari Pepy Dwi , Widyowati Retno , Ervianti Evy , Sawitri Sawitri , Rahmadewi Rahmadewi , Harningtyas Citra Dwi
Published: August 2022

Candida species are causative microorganisms of oropharyngeal, vulvovaginal, and skin infections. Clove (Syzygium aromaticum L.) and eugenol oil have considerable antifungal activity against human pathogenic fungi, including Candida species. The anticandidal action of the studied oils is significantly dependent on the concentration of eugenol and further main and minor constituents of the oils with well-known antifungal effects must have additional and synergistic activities. This study was conducted to compare the antifungal activity of clove leaf essential oil (Syzygium aromaticum L.) and eugenol to determine the role of the content other than eugenol in clove leaf essential oil as an antifungal against Candida species isolates from HIV-AIDS patients. Methods: This study is an in vitro test using the disk diffusion method to determine the zone of inhibition of clove leaf essential oil (Syzygium aromaticum L.) concentrations of 5%, 10%, and 15% as well as eugenol which was equivalent to the concentration of eugenol in clove leaf essential oil at concentrations of 5%, 10% and 15% in 40 isolates of Candida species.
Project scheduling based on resource leveling using fuzzy ranking and genetic algorithm
Authors: Sadegheih Ahmad , Nazari Alireza , Tehrani Reza
Published: August 2022

Project planning and scheduling is often addressed in the paradigm of combined and fuzzy optimization, which is largely owing to the inherent features of the combination and the ensuing uncertainty in determining the variables, none more significant than the timetables and deadlines of activities. As such, the purpose of the current study is to present a novel metaheuristic model for the aforementioned problem by applying fuzzy ranking and genetic algorithm on the resource leveling indicator. This method will be case-studied on fuzzy numbers needed to express uncertain variables in the real world. Project planning and scheduling using resource leveling and the fuzzy approach is of paramount significance to the industry, as it has shown to greatly ensure the proper and effective use of resources. This research seeks to propose a new model for project scheduling in which the uncertainty of the timetable of the activities and resource levelling are examined at the same time. To generate the initial population in the genetic algorithm, parallel fuzzy prioritization method is used to optimally level the resources, while fuzzy theory is further employed to model the uncertainty of the duration of activities.
Assessing the efficacy of parenteral iron therapy in treating pregnancy anemia of mild to moderate severity
Authors: Patil Poonam Atul , Joshi Padmaja Satyen
Published: August 2022

Background: Anemia is a clinical condition characterized by the decreased number of red blood cells or their capacity to carry oxygen needed for physiological functions. Hemoglobin (Hb) value less than 2 standard deviations, less than the median value for healthy subjects matched for pregnancy status, smoking, altitude, gender, and age. Anemia is commonly seen in pregnancy where intravenous iron has proven to be highly effective as a treatment even in cases where oral iron seems ineffective. Aim: The present study was conducted to assess the efficacy of parenteral iron therapy in treating pregnancy anemia of mild to moderate severity. Materials and methods: The present study included 120 pregnant females having confirmed diagnoses of iron deficiency anemia. All the included subjects were given 100mg Mebendazole in a dose twice daily as an anti-helminthic therapy for 3 days duration. Also, during the therapy, folic acid was given to all the subjects. Stool examination for cyst and ova, urine culture, microscopy, and routine urine examination, Renal function test (RFT) was done for all the subjects. Results: The results of the present study showed that significant changes were seen in various hematologic parameters from baseline to follow-up.
Face recognition based banking system using machine learning
Authors: Mohanraj K. C. , Ramya S. , Sandhiya R.
Published: August 2022

The main ideal of this design is to recognize human face and extracting corresponding bank details to bank account users. It helps people to know about their regular transactions and it saves more time in banks. Face is the pivotal part of the human body that uniquely identifies a person. Using the face characteristics as biometric, the face recognition system can be enforced. The most demanding task in all banks is facing unwanted crowds for simple conditions. In traditional banking system, the bank users are called out by the bank employee commemorative wise to know the details of bank users. By enter the name or account number of the user they come to know about the full details of corresponding user. It takes further time for both users and workers. This model integrates a camera that captures an input image, an algorithm for detecting face from an input image, encoding and identifying the face, delivering the banking details directly to the bank users.