bluuebunny/crossref_metadata_2025 huggingface dataset:
Phase Type Viewpoint Spectrum Sensing for Cognitive Radios
Authors: Amini Mohammadreza , Mirzavandi Asra
Published: August 2015

Spectrum sensing is one of the main functionalities of cognitive radios to find transmission opportunities without interfering primary users’ transmission. The more accurate and efficient the spectrum sensing is, the higher the throughput of secondary and primary networks is achieved. This paper presents adaptive spectrum sensing method based on phase type modelling that is computationally efficient for secondary users to conclude about the channel state (idle or busy) under collision constraint. The parameters of phase type model can be adjusted based on the desired operating point of the receiver sensor in its ROC curve. The presented approach can run a simple trade off between sensing time and the two error probabilities of the receiver sensor i.e. False alarm and Miss-detection, the trade off that cannot be easily achieved in other sensing method.
Structure, function, evolution, and application of bacterial Pnu-type vitamin transporters
Authors: Jaehme Michael , Slotboom Dirk Jan
Published: August 2015

Many bacteria can take up vitamins from the environment via specific transport machineries. Uptake is essential for organisms that lack complete vitamin biosynthesis pathways, but even in the presence of biosynthesis routes uptake is likely preferred, because it is energetically less costly. Pnu transporters represent a class of membrane transporters for a diverse set of B-type vitamins. They were identified 30 years ago and catalyze transport by the mechanism of facilitated diffusion, without direct coupling to ATP hydrolysis or transport of coupling ions. Instead, directionality is achieved by metabolic trapping, in which the vitamin substrate is converted into a derivative that cannot be transported, for instance by phosphorylation. The recent crystal structure of the nicotinamide riboside transporter PnuC has provided the first insights in substrate recognition and selectivity. Here, we will summarize the current knowledge about the function, structure, and evolution of Pnu transporters. Additionally, we will highlight their role for potential biotechnological and pharmaceutical applications.
Humorous communication, verbal aggressiveness, and father–son relational satisfaction
Authors: Neuendorf Kimberly A. , Rudd Jill E. , Palisin Paul , Pask Elizabeth B.
Published: August 2015

This study examines the role of humor orientation and reported humorous communication behaviors during father–son conflict in predicting relational satisfaction. In addition, the main effect and interaction effect (with humor orientation) of verbal aggressiveness on relational satisfaction is investigated. A survey of adult father–son pairs pinpoints an interesting network of findings linking general humor orientations, verbal aggressiveness, reported use of humorous messages during conflict, and relational satisfaction within the father–son relationship. Key findings include: Sons’ relational satisfaction is predicted by lower fathers’ verbal aggressiveness for those with fathers who report a very high humor orientation. On the other hand, fathers’ relational satisfaction is predicted by lower levels of sons’ humor orientation, and not by verbal aggressiveness. Further, sons’ relational satisfaction is negatively related to the reported use of
Multi-Objective Optimization of the Pasteurization Process of Pumpkin Cubes Packaged in Glass Jars
Authors: Lespinard Alejandro R. , Arballo Javier R. , Taus Francisco J. , Mascheroni Rodolfo H.
Published: August 2015

The influence of particle size (PZ) and processing temperature (PT) on quality attributes and processing time of pumpkin cubes packaged in glass jars were evaluated during their pasteurization. Second-order polynomial models were developed for the following responses: texture retention (TR), total colour change (TCC) and heating time (HT), using multiple linear regression for a range of operating conditions (20–30 mm and 85–100°C for PZ and PT, respectively). A combination of the polynomial models with the methodology of desirability function was used for optimization of the pumpkin pasteurization process. The obtained optimal conditions were 20 mm and 100°C for PZ and PT, respectively; in order to obtain TR of 82.21%, TCC of 7.54 and HT of 44.97 min. However, these optimal conditions change to 100°C and 21 mm and the responses obtained are TR of 73.60%, TCC of 7.52 and HT of 39.66 min, when the processing time is prioritized.
An Efficient Biological Treatment on Dairy Wastewater by Lactobacillus
plantarum: Mathematical Modeling and Process Parameters Optimization
Authors: Golalikhani Mahshid , Razavi Seyed Hadi
Published: August 2015

The ability of Lactobacillus
plantarum for biological treatment of dairy wastewater was investigated using a response surface method. The effects of three culture condition parameters of temperature (24.93–40.07°C), pH (4.3–6.7), and agitation rate (99.5–200.5 rpm) on the removal efficiency of sugar, total protein content (TPC), and chemical oxygen demand (COD) of the wastewater were studied. For each response parameter, a second-order polynomial model versus independent variables (p < 0.0001) was determined and statistically obtained with high coefficient of determination values (R
2 > 0.95). Numerical optimization defined the optimum treatment conditions for achieving the highest removal efficiency was temperature of 28°C, pH of 5.03, and agitation rate of 147.51 rpm. Under the optimum condition, the removal efficiency values for sugar, TPC, and COD were predicted to be 72.18%, 54.51%, and 78.99%, respectively.
Effects of long-term administration of aspartame on biochemical indices, lipid profile and redox status of cellular system of male rats
Authors: Adaramoye Oluwatosin A. , Akanni Olubukola O.
Published: August 2015

Background: Aspartame (N-L-α-aspartyl-L-phenylalanine-1-methyl ester) (ASP) is a synthetic sweetener used in foods and its safety remains controversial. The study was designed to investigate the effects of long-term administration of aspartame on redox status, lipid profile and biochemical indices in tissues of male Wistar rats.

Methods: Rats were assigned into four groups and given distilled water (control), aspartame at doses of 15 mg/kg (ASP 1), 35 mg/kg (ASP 2) and 70 mg/kg (ASP 3) daily by oral gavage for consecutive 9 weeks.

Results: Administration of ASP 2 and ASP 3 significantly increased the weight of liver and brain, and relative weight of liver of rats. Lipid peroxidation products significantly increased in the kidney, liver and brain of rats at all doses of ASP with concomitant depletion of antioxidant parameters, viz. glutathione-s-transferase, glutathione peroxidase, superoxide dismutase, catalase and reduced glutathione. Furthermore, ASP 2 and ASP 3 significantly increased the levels of gamma glutamyl transferase by 70% and 85%; alanine aminotransferase by 66% and 117%; aspartate aminotransferase by 21% and 48%; urea by 72% and 58% and conjugated bilirubin by 63% and 64%, respectively. Also, ASP 2 and ASP 3 significantly increased the levels of total cholesterol, triglycerides and low-density lipoprotein cholesterol in the rats. Histological findings showed that ASP 2 and ASP 3 caused cyto-architectural changes such as degeneration, monocytes infiltration and necrotic lesions in brain, kidney and liver of rats.

Conclusions: Aspartame may induce redox and lipid imbalance in rats via mechanism that involves oxidative stress and depletion of glutathione-dependent system.
Amelioration of chronic inflammation and oxidative stress indices in diabetic Wistar rats using methanol leaf extract of Bridelia micrantha (Hochst) Baill. (Euphorbiaceae)
Authors: Nwaehujor Chinaka O. , Udegbunam Rita I. , Ode Julius O. , Asuzu Onyeka V.
Published: August 2015

Background: Ethnopharmacological practitioners in Nigeria have used aqueous and ethanol extracts of Bridelia micrantha leaves to manage conditions associated with inflammation, and these include diabetes, chest pain, edema, arthritis and joint pains. This study aimed to evaluate the effects of methanol leaf extract of B. micrantha on chronic inflammation and oxidative stress which accompany diabetic conditions, in streptozotocin-induced diabetic Albino Wistar rats.

Methods: The dried leaves were extracted by percolation in 80% methanol:water for 72 h after which the mixture was filtered using Whatman No. 1 (11 μm) filter papers. Acute toxicity studies were done using Wistar rats and given orally up to a dose of 2,000 mg/kg. The animals were monitored for 48 h. The experimental design involved five (5) groups of six (6) albino Wistar diabetic rats each. Groups A, B and C rats received 100, 200 and 400 mg/kg B. micrantha respectively while groups D (negative control) and E (positive control) rats received 10 mL/kg normal saline and 200 mg/kg acetylsalicylic acid (ASA) respectively by gastric gavage for 7 days. Two sterilized cotton pellets (10 mg each) were implanted subcutaneously into both sides of the dorsal area of each diabetic rat in all the groups. Post cotton pellet implantation, rats in three groups (A, B and C) were treated with 100, 200 and 400 mg/kg B. micrantha extract, while those in two groups (D and E) were treated with acetyl salicylic acid (ASA 200 mg/kg) and normal saline (10 mL/kg) respectively by gastric gavage for 7 days. Serum obtained from the animals on Day 8 of the cotton pellet test were used for malondialdehyde (MDA), catalase, superoxide dismutase (SOD) and glutathione (GSH) assays.

Results: The administration of the leaf extract up to a dose of 2,000 mg/kg to rats produced absolutely no death or observable signs of toxicity in 48 h. The cotton pellet granuloma weights in 200 mg/kg (44.88±1.2 mg), 400 mg/kg (42.10±1.2 mg) B. micrantha extract treated groups and ASA at 200 mg/kg (43.25±1.8 mg) were significantly lower compared to weight of granuloma (85.50±3.2 mg) obtained in the group treated with normal saline. Serum malondialdehyde (MDA) level in the 200 mg/kg (3.32±0.72 nmol/mL) and 400 mg/kg (1.88±1.27 nmol/mL) B. micrantha extract treated groups were significantly (p<0.05) lower compared to MDA level (6.88±0.79 nmol/mL) in the serum of normal saline treated group. Treatment of diabetic rats with the B. micrantha extract also caused significant (p<0.05) elevation in serum catalase, SOD and GSH levels.

Conclusions: The study showed that B. micrantha methanol leaf extract significantly inhibited some chronic inflammation and oxidative stress parameters in diabetes mellitus.
Romanian Legal Structure of Agricultural Holdings in the Context of the Common Agricultural Policy 2014-2020
Authors: Bercean Radu Vlad
Published: August 2015

This Article "Legal structure of agricultural holdings romanian in the context of the common agricultural policy 2014-2020” falls within the field of agricultural research oriented structures, aiming to achieve a documentation of previous research, describe the existing situation and formulating its explanations.
Crimes Against the Carrying out of Justice in the Context of the Current Criminal Law
Authors: Sabau Georgeta Valeria , Cioia Pantilimon
Published: August 2015

The passing of the new codes was justified by the legislator by taking into account both the comparative law in the field, as well as the social and economic realities, the evolution of the doctrine and jurisprudence, the need for readjusting the punitive treatment within the normal limits, the simplification of the incriminatory texts and the need to avoid the overlapping of various criminal provisions.

The current paper aims to analyze the offenses against the justice process, which have come to know new nuances in the current penal configuration, being distinctively specified in Title IV of the Penal Code‟s Special Part; the syntagm “Crimes hindering justice” has been replaced with “Crimes against the carrying out of justice”, since these crimes have not always effectively prevented justice from being carried out; sometimes they only posed a threat to the justice process. The changes regarding these offenses were justified by the legislator by invoking the need to ensure the legality, impartiality, independence and unwavering nature when carrying out the justice process, new incriminations being brought up and other criminal acts being rethought, which were already criminalized by the previous legislation.
Influence of Thin-Wall Structure on Stress Distribution of Curvic Couplings
Authors: Yuan Shuxia , Zhang Youyun , Zhu Yongsheng
Published: August 2015

The objective of this paper is to investigate the influence of transition structure between curvic teeth and disk on stress distribution of curvic couplings, and provide data to help improving the design of curvic couplings. In this work, the three-dimensional finite element method was used, and Augmented Lagrange Algorithm was adopted to the contact algorithm during the analysis. According to the results of this paper, designing thin-wall structure reasonably can avoid detaching of contact interface at external diameter during preload process; reduce stress fluctuation of curvic teeth caused by circumferential bolts structure; and balance stress difference of each contact pair caused by different disk quality under the action of the centrifugal force.
Investigation on Influence of Speed on Rolling Resistance of Belt Conveyor Based on Viscoelastic Properties
Authors: Lu Yan , Lin Fu-Yan , Wang Yu-Chao
Published: August 2015

Since indentation rolling resistance accounts for the major part of total resistance of belt conveyor, it is important to compute it using a proper method, during the design and application study of the belt conveyor. Firstly, an approximate formula for computing the indentation rolling resistance is offered. In this formula, a one-dimensional Winkler foundation and a three-parameter viscoelastic Maxwell solid model of the belt backing material are used to determine the resistance to motion of a conveyor belt over idlers. The velocity of belt is an important operating parameter in the working conditions of the belt conveyor. What’s more, a set of experimental apparatus, which can measure the value of indentation rolling resistance is designed. Author obtains a series of measured data under the different belt speeds with the help of experimental apparatus. Finally, a computation example, that is provided for a typical rubber compound backing material, shows the comparison between the measured and the theoretical results, which offers the influence of speed on the rolling resistance.
Analysis of Mixed Mode I/II/III Fracture in Foam Core Sandwich Structures Using Imposed Displacement Split Cantilever Beams
Authors: Rizov V.
Published: August 2015

Static fracture in foam core sandwich structures under mixed mode I/II/III loading conditions was studied theoretically. In order to generate such loading conditions, a thread guide was used to impose in- plane displacements of the lower crack arm of a sandwich Split Cantilever Beam (SCB). The upper crack arm was loaded by a transverse force. A three-dimensional finite element model of the imposed displacement sandwich SCB configuration was developed. The fracture was studied applying the concepts of linear-elastic fracture mechanics. The strain energy release rate mode components distribution along the crack front was analyzed using the virtual crack closure technique. The influence of the imposed displacement magnitude and the crack length on the fracture was evaluated. The effect of the sandwich core material on the mixed-mode I/II/III fracture was studied. For this purpose, finite element simulations were carried-out assuming that the core is made by different rigid cellular foams. It was found that the strain energy release rate decreases when the foam density increases.
Behaviour of Bi-Adhesive in Double-Strap Joint with Embedded Patch Subjected to Bending
Authors: Temiz Şemsettin , Adin Hamit , Sülü Ismail Yasin
Published: August 2015

In this study, behaviour of bi-adhesive used in the repair of damaged parts was analyzed, using the finite element method. In a double-strap joint with an embedded patch, patch is embedded into the adherents for structural requirements. In addition, to increase the strength of the joint, two adhesives are used to bond the adherents. This approach reduces stress concentration at the overlap ends, increases the load capacity and delays the failure. These effects give rise to higher joint strength. For this purpose, a stiff adhesive, FM73 produced by Cytec Fiberite, was applied in the middle portion of the overlap, while a softer adhesive, SBT9244 from 3M, was applied towards the edges, prone to stress concentrations. Non-linear finite element analyses were carried out to predict the failure loads, to assist with the geometric design and to identify effective ratios of sizes to maximize joint strength.
Apocalyptic Kingship, Harmony and Political Expediency: the Challenges and Paradoxes of Andrew Marvell’s “First Anniversary”
Authors: Jajtner Tomáš
Published: August 2015

The following paper deals with the interpretation of one of the major “Cromwellian” poems of Andrew Marvell (1621-1678), “The First Anniversary of the Government under His Highness the Lord Protector”, 1655. The poem is first set in the context of Marvell’s poetry and his public career in the period between 1637 and 1660. The article then identifies and analyses three main themes of “The First Anniversary”: the notion of a new aeon starting with Cromwell’s rule and the apocalyptical imagery related to his Protectorate, the concept of his power and authority between liberty and tyranny, and the relation between the harmony established by Cromwell and classical Pythagorean harmonious lore. The author argues that the imagery Marvell uses to describe the nature of the regime (especially the concept of Cromwell’s “no-kingship”) shows a deeply paradoxical structure, which uncovers the frailty and insecurity of Cromwell’s dictatorship as well as the circular logic of its justification. In that sense, the poem can be read as a vivid manifestation of the dilemmas and tensions of this period.
“A Poetics of Disruption”: Farida Karodia’s A Shattering of Silence and the Exiled Writer’s Dihiliz Position
Authors: Alonso-Breto Isabel
Published: August 2015

Bearing in mind Edwidge Danticat’s ideas about writing being a dangerous affair, this paper reflects on authorial matters regarding Farida Karodia’s A Shattering of Silence (1993). Like other novels set in times of conflict, A Shattering of Silence can be seen to deploy what the researcher chooses to call a “poetics of disruption”. This is a poetics heavily at the service of politics, intended to disrupt and destabilise the blunt binaries lying at the heart of any armed conflict. In this sense, the main character in the story, Faith, embodies a poetics of disruption in so much as she problematises the binary dimension of the political situation in the Mozambique of the period, being a white woman who sympathises with the anti-colonial struggle. This article claims that, reproducing the dynamics of the poetics of disruption in a process which can be said to replicate that of her character, Farida Karodia herself makes the most of her strategic location in a liminal terrain across nations. Her position as an exilic author can be defined as dihiliz, that is, as a threshold vantage point which enables her to be both inside and outside the situation she reflects about. Karodia’s liminality is here more pointed than is usually the case with the exilic writer, since she chooses to write about Mozambique, in many senses close to her country of origin yet not her birth-place.
Hedging in Political Discourse: Evidence from the Speeches of King Abdullah II of Jordan
Authors: Rabab’ah Ghaleb , Abu Rumman Ronza
Published: August 2015

This paper reports on the findings of a study that aimed to identify the linguistic items which act as hedges in the speeches of King Abdullah II of Jordan, as well as to examine the pragmatic functions of these devices. Twenty-five political speeches of King Abdullah II, randomly selected from the official website of King Abdullah (see Appendix), were analyzed adopting Salager-Meyer’s (1994) taxonomy. The study revealed that the most frequently used hedging device in King Abdullah’s speech is modal auxiliaries, and the most frequently used hedging device subcategory is the modal auxiliary “can”. The findings suggest that these hedging devices fulfil several pragmatic functions. These findings contribute to understanding that speaking a second language (Arabic, in the case of King Abdullah II) neither affects the types of hedging devices nor the functions these devices perform. Moreover, contrary to scientific discourse (e.g., medicine), the research concludes that political discourse as a non-scientific genre resorts to hedging devices to express indirectness, politeness, lack of commitment and probability.
The “biological chamber” method – use of autologous platelet-rich plasma (PRP) in the treatment of poorly healing lower-leg ulcers of venous origin
Authors: Waniczek Dariusz , Mikusek Wojciech , Kamiński Tomasz , Wesecki Mariusz , Lorenc Zbigniew , Cieślik-Bielecka Agata
Published: August 2015

Wound healing is a complex pathophysiological process, in which platelets play a crucial role. Platelet alpha-granules release growth factors to the wound bed; the factors are necessary in the healing process. In chronic wounds, such as poorly healing lower-leg ulcers of venous origin, there is decreased activity of multiple growth factors, so the concept of exogenous delivery of such factors seems a logical strategy. Platelet-rich plasma therapy in patients with lower-leg ulcers of venous origin combined with conventional treatment methods (previously ineffective in these patients) seems, based on our observation, an important adjunct leading to recovery.

The aim of the study was to present an original method of autologous platelet-rich plasma application through the creation of a sort of “biological chamber” containing a concentrate of growth factors.

Material and methods. The described therapy was implemented in 10 patients, who had been ineffectively treated for more than one year in the outpatient setting. Patients with exacerbation of inflammatory process, signs of wound infection and ankle brachial pressure index < 0.8 were excluded from the study. After the application of platelet-rich plasma, further treatment was continued with the use of moist therapy and compression therapy according to a uniform regimen.

Results. Complete healing was achieved within 4-10 weeks from the beginning of the product administration in all patients.

Conclusion. The presented method seems technically simple, effective and relatively inexpensive
Problems concerning patients’ qualification for surgical procedures allowing for evaluation of the condition of axillary fossa lymph nodes in the radical treatment of breast cancer
Authors: Nowikiewicz Tomasz , Śrutek Ewa , Zegarski Wojciech
Published: August 2015

The presence of metastases in the lymph nodes of the axillary fossa is the most important prognostic factor in patients with breast cancer. The surgical treatment option required for evaluation of the condition of the axillary lymph nodes depends on the results of a preoperative physical examination of the patients.

The aim of the study was to evaluate the correctness of breast cancer patients’ qualification to surgical procedures allowing for evaluation of the condition of the axillary lymph nodes.

Material and methods. A retrospective analysis of a group of 963 patients with a diagnosed malignancy of the breast, treated surgically in the period from 01 Jan 2011 to 29 Feb 2012. Depending on the result of evaluation of the axillary lymph node clinical condition, the patients underwent sentinel lymph node biopsy or elective axillary lymphadenectomy.

Results. In 27.4% of patients subjected to excision of the sentinel lymph node, metastatic lesions were found in the lymph nodes removed during the procedure. In most cases (98.1%) that concerned the lymph nodes of the lower part of the axilla. In 17.4% of patients, metastases were located also in the middle or upper part (9%). In the group of patients primarily qualified to lymphadenectomy, the metastatic lesions in the axillary lymph nodes were diagnosed in 67.2% of patients. They were most commonly located in the lower part of the axillary fossa (in 96.7% of cases), and in 68.8% of patients in the middle or upper part (35.8%).

Conclusions. Biopsy of the sentinel lymph node in patients with clinically advanced breast cancer is an effective and safe method of evaluation of the condition of the axillary fossa lymph nodes. A high rate of false positive results concerning the clinical stage of the disease requires changing the rules of patients’ qualification to elective axillary lymphadenectomy.
Conservative surgery for pancreatic neck transection
Authors: Dahiya Divya , Singh Rana Surinder , Kaman Lileswar , Behera Arunanshu
Published: August 2015

Pancreas is the fourth solid organ injured in blunt abdominal trauma. Isolated pancreatic injury is present in less than 1% of patients. As it is associated with high morbidity and mortality, management is controversial.

Isolated pancreatic trauma cases with pancreatic neck transection following blunt abdominal trauma were analyzed. All these patients were treated with immediate surgery involving lesser sac drainage and feeding jejunostomy only.

Authors conclude that lesser sac drainage can be used as an alternative to distal pancreatectomy or pancreaticojejunostomy or pancreaticogastrostomy.
Endoscopic esophageal self-expanding stent implantation WallFlex™ (boston scientific) in the management of a gastrocutaneous fistula, as a complication of sleeve bariatric gastrectomy
Authors: Janczak Dariusz , Pawłowski Wiktor , Ziomek Agnieszka , Dorobisz Tadeusz , Janczak Dawid , Janus Werner , Chabowski Mariusz
Published: August 2015

The study presented a case of a gastrocutaneous fistula, as a result of bariatric sleeve gastrectomy. The discussion considered the main pathogenesis, etiology, diagnostics and endoscopic treatment using the implantation of covered esophageal stents. Special attention was placed upon the multifactorial origin of this life-threatening clinical condition, typical for bariatric surgery
Therapeutic approach in monosymptomatic nasal obstruction
Authors: Enache Raluca , Sarafoleanu Dorin
Published: August 2015

The term monosymptomatic nasal obstruction does not refer to the isolated nasal obstruction, but to a nasal pathology in which nasal obstruction is the predominant symptom. Four nasal structures may be involved in the isolated monosymptomatic nasal obstruction: the inferior nasal turbinates, the nasal septum or the nasal valve. Since the phenomenon of nasal obstruction can be due to various diseases, correct assessment of the patient is very important. Correctly performed anamnesis and clinical and paraclinical evaluations can help determine the definite diagnosis and choose the therapeutic strategy indicated in each individual case.

In this review the authors present the proper therapeutic approach for each type of monosymtpomatic nasal obstruction, emphasizing the need of a preoperatory detailed and correct investigation and diagnosis.
The role of PLUNC proteins in the etiopathogeny of chronic rhinosinusitis
Authors: Manea Claudiu , Sarafoleanu Codrut , Iosif Cristina , Patrascu Elena
Published: August 2015

BACKGROUND. Innate immunity represents the first way of protection against different pathogenic agents. Recently, it has been a permanent interest regarding an innate immune molecule, that is known as palate, lung, nasal epithelial clone (PLUNC). PLUNC is a specific result found in the airways, of approximately 25 kDa, whose encoding is realized by adjacent genes located within a region of 300 kb in chromosome 20; these proteins must be detected predominantly in the superior respiratory tract.

MATERIAL AND METHODS. We performed a prospective clinical study on 34 patients with chronic rhinosinusitis and 10 controls, in order to investigate the expression of this protein in nasal tissue of patients affected by chronic rhinosinusitis. We tested the correlation between the existence of this disease and PLUNC proteins positivity.

RESULTS. 100% of controls have a+++ rated PLUNC proteins positivity, while cases have a lower percentage of positivity. There were no differences statistically significant between patients with CRSwNP and those with CRSsNP.

CONCLUSION. As a response to different irritating agents (bacteria, viruses, chemical factors), nasal mucosa will react by producing PLUNC proteins. PLUNC proteins have a defensive role in the upper airways mucosa.
The importance of computerized dynamic posturography in vestibular rehabilitation of patients with unilateral peripheral vestibular deficiency
Authors: Ulmeanu Anamaria Andreia , Didilescu Andreea , Enache Raluca , Musat Gabriela , Sarafoleanu Codrut
Published: August 2015

OBJECTIVE. To evaluate the importance of computerized dynamic posturography in vestibular rehabilitation of patients with unilateral peripheral vestibular deficiency syndrome.

MATERIAL AND METHODS. The study was conducted on a group of 30 patients (33-78 years; mean age (± SD) = 55.8 ± 12.12) diagnosed with unilateral peripheral vestibular deficiency syndrome, which benefited from VR on a posturography platform. Assessment of the patients was made using the Sensory Organization Test before and after eight sessions of rehabilitation. We analyzed the results obtained with eyes open (EO) and eyes closed (EC) on static and foam platform. The following variables were evaluated: Romberg coefficient, statokinesigram (SKG), maximum amplitude of the degree of deviation in anterior/posterior and medial/lateral planes, SKG and the time interval of the game rehabilitation program.

RESULTS. The statistical analysis of the data revealed a strong correlation (p<0.05) for the studied parameters, especially when the test was performed with the eyes closed on foam platform. The analysis of the Romberg coefficient did not show statistically significant results (p>0.05) and the measured values were outside the range of normality even at the end of the rehabilitation program. SKG and the time interval reference of the game showed significant improvement of the parameters (p<0.05); at the end of the rehabilitation sessions, 93.33% of the patients showed full recovery of their deficit.

CONCLUSION. Computerized dynamic posturography has a particularly important role in the evaluation, monitoring and rehabilitation of the patients with peripheral vestibular deficiency.
Transnasal endoscopy – Evaluation and treatment method for patients with sinus lift and dental implants indications
Authors: Vereanu Anca Delia , Savu Manuela Andra , Patrascu Elena , Sarafoleanu Codrut
Published: August 2015

BACKGORUND. Sinus floor elevation, also known as sinus lift, is the surgical procedure meant to elevate the maxillary floor in order to increase the height of the alveolar bone. This will allow the oral surgeon specialist to insert the desired implants, the ground of dental reconstruction. As the procedure involves the maxillary sinus and its Schneiderian membrane the main concern is to have a healthy maxillary sinus prior to implantation and to the maxillary augmentation.

OBJECTIVE. The aim of our study was to identify the patients with abnormal CT scan and refer them to an ENT evaluation, in order to identify and treat any sinusal pathology that can lead to a poor outcome of the sinus-lift intervention.

MATERIAL AND METHODS. Our prospective study included 15 patients selected from a group of 79 adults, candidates for dental implantation with sinus augmentation. These patients had abnormal sinus CT scan in terms of mucosal hypertrophy, cysts or fungal material. Transnasal diameatic sinusoscopy was performed for all the patients, assessing the aspect of the sinus cavity and the mucosa. The following abnormal aspects were found in our group: 5 patients with cysts, 2 patients with fungus ball and 4 with mucosal hypertrophy. 4 patients had normal maxillary mucosa despite the CT scan appearance.

RESULTS. All the patients with abnormal aspects at sinusoscopy (11 patients) were operated on before sinus lift procedure - antrostomy, cyst removal, fungus ball removal. 4 patients showed normal aspect of the sinus mucosa despite the CT scan donations, meaning a 26.66% error rate in appreciating the real changes of the maxillary mucosa on the CT scan.

CONCLUSION. Endoscopic assessment of the maxillary sinus is mandatory in patients with changes of the CT scan. This allows a proper examination of the sinus mucosa and can predict the outcomes of the sinus lift procedures. It is mandatory to cure the inflammation or infection of the maxillary sinus prior to implant procedure in order to be able to increase the success rate, as it can lead to failures of the implant procedure.
Precession of a Planet with the Multiple Scales Lindstedt–Poincare Technique
Authors: Pakdemirli Mehmet
Published: August 2015

The recently developed multiple scales Lindstedt–Poincare (MSLP) technique is successfully applied to a mathematical model of planet motion. The equation is originally developed to precisely understand the orbital motion of the planet Mercury around the Sun and the precession of the orbit due to the relativistic effects. The quadratic nonlinear equation is solved by the classical Lindstedt–Poincare method (LP) and then by the newly developed multiple scales Lindstedt–Poincare method (MSLP). Both approximate solutions are contrasted with the numerical simulations. When the relativistic effects are small, all three solutions coincide with each other. When the perturbation effects are increased, the MSLP solutions agree better with the numerical solutions than the LP solutions. The precession of the perihelion of the planet is calculated and compared for the approximate solutions.
A mononuclear cobalt(III) 3-(2-pyridyl)-5-phenyl-1,2,4-triazolato complex: hydrothermal synthesis, crystal structure, thermostability, and DFT calculations
Authors: Liu Huaixian , Sun Lin , Zhou Huiliang , Cen Peipei , Jin Xiaoyong , Liu Xiangyu , Hu Qilin
Published: August 2015

Starting with 1H
-3-phenyl-5-(pyridin-2-yl)-1,2,4-triazole (1-Hppt), a Co(III) complex, [Co(ppt)3] (1), has been synthesized by reaction with CoF3 under hydrothermal conditions and characterized by its infrared spectrum and elemental analysis. The structure was determined by single-crystal and powder X-ray diffraction. Density functional theory (DFT) was employed to determine the optimized geometry and preferred conformation of the free ligand. A supramolecular network is formed via π–π stacking interactions. The conformation and geometry of the ligands correspond with the calculated results.
RasGRF1 regulates the hypothalamic–pituitary–adrenal axis specifically in early-adolescent female mice
Authors: Uzturk Belkis Gizem , Jin Shan-xue , Rubin Beverly , Bartolome Christopher , Feig Larry A
Published: August 2015

Dysregulation of the hypothalamic–pituitary–adrenal (HPA) axis has been implicated in the induction and prolongation of a variety of psychiatric disorders. As such, much effort has been made to understand the molecular mechanisms involved in its control. However, the vast majority of the studies on the HPA axis have used adult animals, and among these the majority has used males. Here we show that in knockout mice lacking the guanine nucleotide exchange factor, RasGRF1, habituation to 30 min/day of restraint stress is markedly accelerated, such that these mice do not display elevated corticosterone levels or enhanced locomotion after 7 days of stress exposure, like WT mice do. Strikingly, this phenotype is present in early-adolescent female RasGRF1 knockout mice, but not in their early-adolescent male, mid-adolescent female, adult female or adult male counterparts. Moreover, not only is there a clear response to restraint stress in early-adolescent female RasGRF1 knockout mice, their response after one, three and five exposures is magnified approximately threefold compared to WT mice. These findings imply that distinct mechanisms exist to regulate the HPA axis in early-adolescent females that involves RasGRF1. A full understanding of how RasGRF1 controls the HPA axis response to stress may be required to design effective strategies to combat stress-associated psychiatric disorders initiated in young females.
KIF1-binding protein interacts with KIF3A in haploid male germ cells
Authors: Lehti Mari S , Kotaja Noora , Sironen Anu
Published: August 2015

Male fertility relies on the production of functional spermatozoa. Spermatogenesis is a complex differentiation process that is characterized by meiosis and dramatic morphogenesis of haploid cells. Spermatogenesis involves active changes in the microtubular network to support meiotic divisions, cell polarization, the reshaping of the nucleus, and the formation of a flagellum. Previously, we have demonstrated that a microtubule-based anterograde transport motor protein KIF3A is required for the sperm tail formation and nuclear shaping during spermatogenesis. In this study, we show that KIF3A interacts with a KIF1-binding protein (KBP) in the mouse testis. We have characterized the expression and localization pattern of KBP during spermatogenesis and localized both KIF3A and KBP in the cytoplasm of round spermatids and manchette of elongating spermatids. Interestingly, KBP localized also in the late chromatoid body (CB) of elongating spermatids, whose function involves intracellular movement and association with the microtubular network. Altogether our results suggest a role for KBP in spermatid elongation and in the function of the late CB.
High-Resolution Global Analysis of the Influences of Bas1 and Ino4 Transcription Factors on Meiotic DNA Break Distributions in Saccharomyces cerevisiae
Authors: Zhu Xuan , Keeney Scott
Published: August 2015

Meiotic recombination initiates with DNA double-strand breaks (DSBs) made by Spo11. In Saccharomyces cerevisiae, many DSBs occur in “hotspots” coinciding with nucleosome-depleted gene promoters. Transcription factors (TFs) stimulate DSB formation in some hotspots, but TF roles are complex and variable between locations. Until now, available data for TF effects on global DSB patterns were of low spatial resolution and confined to a single TF. Here, we examine at high resolution the contributions of two TFs to genome-wide DSB distributions: Bas1, which was known to regulate DSB activity at some loci, and Ino4, for which some binding sites were known to be within strong DSB hotspots. We examined fine-scale DSB distributions in TF mutant strains by deep sequencing oligonucleotides that remain covalently bound to Spo11 as a byproduct of DSB formation, mapped Bas1 and Ino4 binding sites in meiotic cells, evaluated chromatin structure around DSB hotspots, and measured changes in global messenger RNA levels. Our findings show that binding of these TFs has essentially no predictive power for DSB hotspot activity and definitively support the hypothesis that TF control of DSB numbers is context dependent and frequently indirect. TFs often affected the fine-scale distributions of DSBs within hotspots, and when seen, these effects paralleled effects on local chromatin structure. In contrast, changes in DSB frequencies in hotspots did not correlate with quantitative measures of chromatin accessibility, histone H3 lysine 4 trimethylation, or transcript levels. We also ruled out hotspot competition as a major source of indirect TF effects on DSB distributions. Thus, counter to prevailing models, roles of these TFs on DSB hotspot strength cannot be simply explained via chromatin “openness,” histone modification, or compensatory interactions between adjacent hotspots.
Comportamento violento entre usuários de crack
Authors: Botti Nadja Cristiane Lappann , Machado Jacqueline Simone de Almeida
Published: August 2015

Considerando a relevância do uso abusivo de crack na atualidade brasileira e sua relação com a violência, este estudo propõe-se a analisar a associação entre comportamento violento —delitivo, auto e hetero
agressivo— entre os usuários de crack e variáveis sociodemográficas e de uso de drogas. Realizado estudo quantitativo, transversal, com amostra de conveniência, com 72 homens usuários de crack em tratamento nas Comunidades Terapêuticas de seis cidades da região Oeste
do Estado de Minas Gerais (Brasil). Os dados foram analisados estatisticamente no Statistical Package for
the Social Sciences Versão 17.0, utilizando-se teste qui-quadrado para verificação de diferenças estatisticamente
significantes. Os resultados apontam associação do tráfico com número de pedras consumidas e de tratamentos realizados; de prisão ou detenção com baixa escolaridade,
ser solteiro e idade de início do uso de droga ilícita; de tentativa de suicídio com o tempo máximo de
abstinência e de heteroagressão com idade de início do uso de droga ilícita e frequência diária do uso de crack. O uso de crack pode contribuir para o desenvolvimento de comportamento violento —delitivo, auto e heteroagressivo.
Uso de ácidos grasos en la prevención de úlceras por presión y de extremidad inferior
Authors: Restrepo Juan
Published: August 2015

Objetivo: Analizar la literatura científica acerca del uso y la efectividad de los ácidos grasos hiperoxigenados y las actuaciones de los profesionales de enfermería en la prevención y tratamiento de úlceras por presión y heridas crónicas.

Metodología: Se llevó a cabo una revisión bibliográfica de la literatura en las principales bases de datos de las ciencias de la salud y las ciencias sociales (MEDLINE-PUBMED, CINHAL, WEB of SCIENCE, LILACS, SOCIOLOGOCAL ABSTRACTS, CUIDEN, EMBASE, PSYCOINFO e ISI WEB of KNOWLEDGE). Se hizo una revisión analítica de los artículos seleccionados utilizando un protocolo para extraer los datos.

Resultados: Del total de artículos encontrados, 14 reportaron los resultados de ensayos clínicos o estudios cualitativos. Los autores señalaron los beneficios de la utilización de los ácidos grasos hiperoxigenados en la prevención y tratamiento de las úlceras por presión y heridas crónicas.

Conclusiones: En los estudios analizados se identificaron principalmente asuntos sobre la prevención, el tratamiento y el cuidado de enfermería en personas con úlceras crónicas y agudas. Como estrategia
de intervención, se reportó la efectividad de los ácidos grasos hiperoxigenados, lo que permite sugerir el uso protocolizado en el ámbito institucional, bajo la consideración de un plan de cuidados estructurado con la metodología científica del Proceso de Atención de Enfermería.
Notificação da violência intrafamiliar contra crianças e adolescentes por profissionais de saúde no Brasil
Authors: Silva Priscila Arruda da , Lunardi Valéria Lerch , Ribeiro Juliane Portella , Oliveira Adriane M Netto , Vasquez Tânia Cristina Schäfer
Published: August 2015

O presente estudo tem por objetivo analisar as produções científicas acerca da violência intrafamiliar contra crianças e adolescentes notificadas por profissionais de saúde. Trata-se de uma revisão da literatura realizada a partir de artigos, legislações, manuais do Ministério da Saúde, teses, dissertações e livros. Apoiando-se em Foucault, reconhece-
se a notificação como uma manifestação de poder e resistência dos profissionais de saúde e, em especial, das enfermeiras, a um problema tão comum em nossa sociedade, causador de grande impacto social, político e econômico, e com alto potencial
de comprometimento para a saúde e qualidade de vida das vítimas. As questões examinadas neste estudo podem subsidiar a reflexão dos profissionais sobre sua prática, buscando o enfrentamento da violência de forma a prevenir que o ciclo
se reproduza na família.
Cuidados de enfermagem ao paciente no perioperatório de cortico-amigdalohipocampectomía
Authors: Koerich Cintia , Santos Fabiana Cristine dos , Santos José Luís Guedes dos , Erdmann Alacoque Lorenzini , Pauli Carla , Marinho Monique Mendes
Published: August 2015

Este artigo teve como objetivo construir e apresentar um plano de cuidados pré e pós-operatórios para pacientes submetidos à cirurgia de cortico-amígdalo-hipocampectomia
(ahc) para ser implementado em uma unidade de internação cirúrgica de um Hospital Universitário do Sul do Brasil. Trata-se de um relato de experiência desenvolvida durante o Estágio Supervisionado de Enfermagem por graduandos de enfermagem. Construiu-se um plano com 26 cuidados de enfermagem para pacientes submetidos à cirurgia de ahc, que foi validado por profissionais experts da área. Realizaram-se encontros expositivos e dialogados com a equipe de enfermagem para esclarecer e desmistificar a epilepsia, suas diferentes apresentações de crises e possibilidades de tratamento, bem como apresentar o plano de cuidados elaborado. Essa experiência contribuiu com a formação profissional dos estudantes, assim como forneceu
subsídios para a implementação da sistematização da assistência de enfermagem a este paciente específico, considerando o cuidado sistematizado uma ferramenta fundamental no trabalho do enfermeiro.
Reconstruyendo el significado de calidad de vida de los cuidadores en el cuidado: una metasíntesis
Authors: Carreño Moreno Sonia Patricia , Chaparro Diaz Lorena
Published: August 2015

Las enfermedades crónicas no transmisibles afectan la calidad de vida de las personas que las padecen y de sus cuidadores familiares. Se ha demostrado que se cambian los estilos de vida, aparece el dolor y las limitaciones, se altera la socialización y surgen sentimientos de pérdida y muerte. Se requiere por esto hacer una revisión sistemática del conocimiento generado para construir teóricamente
el concepto de calidad de vida de los cuidadores familiares.

Objetivo: Realizar una integración interpretativa a partir de la evidencia científica del fenómeno de calidad de vida de cuidadores de personas con enfermedad crónica.

Método: Metasíntesis de 24 artículos publicados de investigaciones científicas del fenómeno de calidad de vida de cuidadores de personas con enfermedad crónica, de bases de datos electrónicas reconocidas en enfermería y salud a partir del método de Sandelowski y Barroso (2006).

Resultados: Emergió un planteamiento hipotético denominado Reconstruyendo el significado de calidad de vida de los cuidadores en el cuidado que se sustenta en tres momentos  para el significado de calidad de vida: vivir en desasosiego,
vivir para la calidad de vida del otro y construir la propia calidad de vida.

Conclusiones: La reconceptualización de la calidad de vida de los cuidadores genera en el cuidador una forma diferente de percibir su experiencia, la cual está condicionada por los asuntos morales que están asociados a la labor de ser cuidador y las opciones de desarrollo humano con el significado espiritual emergente. La construcción del significado de calidad de vida para el cuidador se da a través de la experiencia de cuidado, edificándose en el ejercicio de su rol de cuidador, el cual responde a factores estrechamente relacionados con lo moral y evoluciona tomando un significado espiritual.