bluuebunny/crossref_metadata_2025 huggingface dataset:
Predictive Value of Immunological Parameters in the Risk of Gestational Diabetes Mellitus: A Pilot Study
Authors: Fagninou Adnette , Nekoua Magloire Pandoua , Fiogbe Salomon Ezéchiel Mahougnon , Moutairou Kabirou , YESSOUFOU Akadiri
Published: November 2020

Background : Immunological and biochemical parameters are gaining more and more importance in the prognosis of diabetes and its complications. Here we assessed the predictive power of immunological parameters correlated with biochemical ones in gestational diabetes mellitus (GDM). Material and Methods : 217 pregnant women were screened for GDM between the 2 nd and the 3 rd trimester of gestation, based on IAGDP methods in this cross-sectional descriptive study. Immunological and biochemical parameters were determined using appropriate methods. Receiver operating characteristics (ROC) curve analyses were conducted to assess the optimal cutoff and value of immunological to biochemical parameter ratios for predicting GDM. Results : 11.90% of pregnant women were diagnosed GDM positive. Serum glucose levels, total cholesterol, LDL-cholesterol, triglycerides and total proteins were significantly increased while HDL-cholesterol decreased in women with GDM compared to controls. The levels of glycosylated hemoglobin and creatinine, as well as transaminase (AST and ALT) activities did not significantly differ between GDM and pregnant controls. Total leucocytes (white blood cell), lymphocyte and platelet numbers were significantly higher in women with GDM than in pregnant controls. We also found that the lymphocyte:HDL-C, monocyte:HDL-C and granulocyte:HDL-C ratios were significantly higher in women with GDM than in pregnant controls ( p = 0.001; p = 0.009 and p = 0.004 respectively). Women with a lymphocyte:HDL-C ratio greater than 3.66 had a 4-fold increased risk of developing GDM than those with lower ratios (odds ratio 4.00; 95% CI: 1.094 – 14.630; p =0.041). Conclusion : The lymphocyte:HDL-C, monocyte:HDL-C and granulocyte:HDL-C ratios may represent valuable makers, and the lymphocyte:HDL-C ratio in particular may have strong predictive power for GDM. This ratio can be easily assessed in patients.
Cultural Management Practices for Commercial Tigernut Production in Southern Ontario, Canada
Authors: Elford Evan , Todd Jim , White Peter , Riddle Rachel , O’Sullivan John , Van Acker Rene
Published: November 2020

To foster development of Ontario commercial tigernut (Cyperus esculentus var. sativus) production, this study was conducted to identify cultural management practices that increase tuber yields. The agronomic practices of field preparation (hilled vs. not hilled), regular irrigation vs. natural rainfall, varying rates of nitrogen (N) fertility, and early season weed management were evaluated. Irrigation had no significant impact on total fresh weight, dry weight, and marketable yield over 2 growing seasons. Similarly, yields from plants grown in hilled rows vs. flat beds over two seasons showed no significant differences. Tigernut yields did not show a response to increasing rates of N up to 150 kg·ha−1. A critical weed-free period of 3 weeks resulted in an 844% yield increase over the nonweeded control. Overall, the results indicate that in general, tigernut requires few inputs to produce a viable commercial yield under Ontario growing conditions.
What does it mean to be a principal? A policy researcher’s perspective on the last 30 years in Aotearoa New Zealand
Authors: Wylie Cathy
Published: November 2020

In this article I reflect on research relating to school leadership and the use of research to support school leadership over the last 30 years in Aotearoa New Zealand. The Tomorrow’s Schools reforms in 1989 wth its shift to school self-management saw more interest in understanding the size and nature of the principal role. More recently there has been interest among policymakers in using research to support effective school leadership, and revived attention to the place of school leadership in Aotearoa New Zealand’s education system.

This article is also intended to provide future Aotearoa New Zealand researchers into school leadership with some references they can use to chart how things change if new policy settings and supports for school leadership are introduced as a result of the Tomorrow’s Schools Independent Taskforce’s recommendations.
Diffusion from convection
Authors: Medenjak Marko , De Nardis Jacopo , Yoshimura Takato
Published: November 2020

We introduce non-trivial contributions to diffusion constants in generic many-body systems with Hamiltonian dynamics arising from quadratic fluctuations of ballistically propagating, i.e. convective, modes. Our result is obtained by expanding the current operator in terms of powers of local and quasi-local conserved quantities. We show that only the second-order terms in this expansion carry a finite contribution to diffusive spreading. Our formalism implies that whenever there are at least two coupled modes with degenerate group velocities the system behaves super-diffusively, in accordance with non-linear fluctuating hydrodynamics. Finally, we show that our expression saturates the exact diffusion constants in quantum and classical interacting integrable systems, providing a general framework to derive these expressions.
Desarrollo de las capacidades nanotecnológicas en las Instituciones de
Educación Superior en Antioquia-Colombia
Authors: Aguirre Echavarría Francisco Javier , López Gómez Maria Del socorro , Durango Yepes Carlos Mario
Published: November 2020

El propósito de este artículo es explorar las capacidades
nanotecnológicas en los grupos de investigación de las Instituciones de
Educación Superior (IES) de Antioquia. La metodología de investigación
seguida es el estudio colectivo de casos, el método de análisis utilizado
fue el de análisis de contenido con la ayuda en la etapa inicial del
Atlas.ti. Como resultado de la investigación, se evidencia una capacidad
nanotecnológica regional embrionaria que avanza en una etapa temprana de
asimilación, donde aún no existe explotación del conocimiento; la
investigación está orientada a la comprensión de los fenómenos de la materia
a nivel nano, no en función de necesidades sociales o empresariales, es
decir, una capacidad exploratoria, los investigadores tienen formación
doctoral y los equipos especializados son de bajo nivel.El artículo se
divide en cinco secciones, incluyendo esta introducción. La segunda sección
define y clasifica las capacidades nanotecnológicas. La tercera sección
describe el diseño metodológico. La cuarta sección presenta los resultados,
y al final, la discusión y las conclusiones.
La automedicación y sus implicaciones en la salud y el bienestar: estudio
de caso, Unidad Hospitalaria Doce de Octubre
Authors: Alzate Cárdenas Martha del Socorro , Suárez Molina Sandra Margarita
Published: November 2020

El presente artículo muestra los resultados de la investigación “La
automedicación y sus implicaciones en la salud y el bienestar: estudio de
caso de la Unidad Hospitalaria Doce de Octubre, en Medellín Colombia”, la
cual tuvo como finalidad realizar un análisis de la automedicación a 156
pacientes adultos mayores entre 60 y 95 años, atendidos por urgencias, que
hacen parte del grupo de mayor riesgo en salud por automedicación. Los
resultados sugieren que la mayoría de las personas desconocen los riesgos de
la automedicación, no están sensibilizadas sobre las implicaciones para la
salud y, en términos generales, acuden a la farmacia para adquirir
medicamentos con el fin de mitigar los problemas de salud.
Fortalecimiento del autoconcepto en niños con discapacidad intelectual y
necesidades en salud
Authors: Ramírez Echavarría Carmen Olivia , Soto Suaza María Caterine
Published: November 2020

El presente artículo de reflexión académica surge a la luz de la
experiencia de la práctica social y se orienta hacia el fortalecimiento del
autoconcepto y la autoestima en niños, niñas y adolescentes con discapacidad
intelectual y necesidades en salud, como uno de los problemas con
significativa ocurrencia en el desarrollo de los procesos de enseñanza y
aprendizaje. En esta investigación se realizó una reflexión sobre la
evolución del concepto de discapacidad intelectual en los entornos
educativos y necesidades en salud por el cáncer. Finalmente, se sugiere una
serie de estrategias para abordar con éxito el acompañamiento a niños, niñas
y adolescentes para el abordaje de las dificultades en salud y en la
discapacidad intelectual. Concluyendo que la discapacidad es una cuestión de
derechos humanos y, por ello, se deben eliminar todos los factores que
atenten contra la promoción, el desarrollo, la educación y el autoconcepto
para con el mejoramiento de sus dificultades personales y/o
sociales.
En el corazón de Medellín: experiencias de un grupo de maestras en torno
a las habilidades sociales
Authors: Cuervo Duque Jennifer , David Higuita Norelia , Guarín Bonilla Yessica Julieth , Herrera Serna Tatiana Yulieth , Valencia Castañeda María Alejandra , Montenegro Velásquez Marcela
Published: November 2020

El presente artículo se basó en varias propuestas de intervención
psicosocial que buscaron fomentar las habilidades sociales de los niños,
niñas y jóvenes en diferentes centros de la ciudad de Medellín (Centro
Comunitario La Torre, Centro Infantil Clara María, Universidad de los niños
y Colegio Bethlemitas), los cuales se vinculan con el espacio de formación
denominado Práctica IV, en conjunto con la Universidad Católica Luis Amigó,
cuya población se visibiliza en diferentes entornos sociales centrada en un
acompañamiento psicosocial. De este modo, la metodología utilizada fue la
observación participante con intervención de algunas técnicas interactivas
(árbol de problema, mural de situaciones, fotolenguaje, entre otras). Lo que
permitió evidenciar que las habilidades sociales son parte fundamental de la
vida diaria del ser humano, cuyo proceso se desarrolla desde la edad
temprana y repercute en edades posteriores, ya sea en forma positiva o
negativa. Por ende, se resalta la importancia de fomentar el manejo de las
emociones, el trabajo cooperativo, la autoestima, la resolución de problemas
y las relaciones interpersonales en los sujetos que se encuentran en el
proceso de formación.
Etapas de formación de los semilleros de investigación para maestros de
lenguas
Authors: Regalado Chicaiza Jennifer Daniela , Vergara Julio Cindy , Abad José Vicente
Published: November 2020

Atendiendo a la importancia de la formación en investigación en los
programas de educación en Colombia, cabe destacar la contribución de los
semilleros de investigación a la formación de nuevos maestros
investigadores. Para aportar a este objetivo, se realizó el presente
artículo reflexivo que recoge las experiencias de las estudiantes
integrantes del semillero Formación de Maestros de Lenguas de la Universidad
Católica Luis Amigó, en conjunto con los resultados de las experiencias de
los estudiantes miembros de semilleros obtenidos en el proyecto “Génesis del
maestro investigador en los semilleros de investigación”. Este artículo
corresponde a una mirada crítica y reflexiva de la experiencia tanto en el
ámbito profesional como personal de los estudiantes como miembros de
semilleros de investigación bajo la guía del investigador principal. El
artículo se centra en dar a conocer las experiencias de los estudiantes en
las diferentes etapas que han vivenciado en su trayectoria formativa de
semillero, como también, anexo al proyecto de investigación, se presenta la
perspectiva de los graduados, para lo cual se recogieron comentarios de
antiguos estudiantes del semillero en mención que ya están en ejercicio de
su profesión. Para finalizar, se concluye que la participación en semilleros
abarca un profundo impacto en los procesos de construcción de identidad
profesional docente y personal y sus implicaciones para la vida
profesional.
La lúdica como mediadora del aprendizaje para el desarrollo integral de
los niños de la primera infancia
Authors: Acevedo Montiel Lizeth Tatiana , Gómez Valencia María Verónica , Ortega Arrieta Jojanis María , Valencia Restrepo María del Pilar , Villa Cardona Luisa Fernanda
Published: November 2020

En el presente artículo se abordará el principio de la lúdica como uno
de los ejes centrales de la educación preescolar, siendo este principio
fundamental para el aprendizaje y el desarrollo integral de los niños y
niñas en la primera infancia. Para sustentar el mencionado principio, este
artículo se basará en las experiencias significativas de la Práctica IV de
intervención psico-social, adscrita a la Licenciatura en Educación Infantil
de la Universidad Católica Luis Amigó, realizada en dos agencias de
diferentes contextos sociales; por tal motivo se contrastan ambos contextos
y se evidencia la implementación de la lúdica como mediador pedagógico en
los entornos sociales y cómo esta puede afectar o favorecer el desarrollo y
el aprendizaje de los niños y niñas.
Calidad a sangre fría
Authors: Flórez González Daniela
Published: November 2020

En el diario acontecer se van encontrando bellas posibilidades para interactuar, lo que permite, entre otras, una rica y fructífera conversación que facilita, en muchos casos, un buen y cálido proceso de aprendizaje. El vínculo puede convertirse en un punto de partida para seguir avanzando hacia la consolidación de una grata y responsable relación interpersonal; empero, es oportuno anotar que la interacción no alude solo a lo que sucede entre individuos, sino además a lo que necesariamente ocurre dentro de una organización o de un sistema, incluso social.
Assessment of the level of local budget financial decentralization: Case of Ukraine
Authors: Dekhtyar Nadiya , Valaskova Katarina , Deyneka Olga , Pihul Nataliya
Published: November 2020

Further improvement of financial relations at the local level and the development of local budgets take place in the context of financial decentralization. This implies strengthening the role of local governments in attracting necessary financial resources to ensure socio-economic development of territories. The purpose of this paper is to identify the impact of decentralization on the state of local budgets and to develop a scientific and methodological approach to assessing the level of financial decentralization of local budgets using the example of Ukraine for 2010–2019. The developed methodology consists of six successive stages. A comparative analysis of the dynamics of indicators of local budget execution in Ukraine in terms of revenues, expenditures and transfers using an integrated index obtained through taxonomic analysis is conducted. As a result of evaluating the effectiveness of the basic principles of financial decentralization, the expediency of calculating the integrated index of local budget financial decentralization is substantiated. This index is formed using intermediate indicators of autonomy to cover expenses and generate income both on the basis of own sources and taking into account the received state transfers for the implementation of their own and delegated powers of local governments. The implementation of the proposed method allow one to assess the levels of financial decentralization of local budgets to establish the degree of financial autonomy and financial self-sufficiency of the territories. The results obtained should be considered when determining the effectiveness of financial support for local budgets in the process of socio-economic development of regions.
Design and analysis of actuator system of electromagnetic shell with high-overload resistances
Authors: Zheng Haoxin , Liu Hongbin , Liu Peiyao
Published: November 2020

The components of an electromagnetic shell system should be able to sustain the impact of high-strength instantaneous acceleration when the system is launched. The dynamic characteristics of high overload present significant challenges in the component (electronic and mechanical) design and part assembly of a steering gear system. This paper proposes a new design strategy for the servo system of a high-overload electromagnetic projectile. First, according to the special environment index parameters of a high-overload electromagnetic shell steering system, a new anti-overload deceleration mechanism that combines a triangular thread lead screw, a shift fork, and the entire anti-high-overload mechanical structure is proposed. The transient dynamic vibration characteristics of the entire high overload are analyzed. Based on the integrated module method for complex mechanical and electrical equipment, a mathematical model of the full closed-loop electromagnetic shell actuator system is established, and its dynamic characteristics are analyzed. Finally, a prototype of the high-overload electromagnetic projectile steering system is manufactured. By testing the maximum rudder deflection angle and the frequency and step responses of the system, the dynamic characteristics of the new high-overload electromagnetic shell actuator system are verified. This study provides a new method for designing high-overload electromagnetic shell steering gears.
Monthly runoff prediction using modified CEEMD-based weighted integrated model
Authors: Yan Xinqing , Chang Yuan , Yang Yang , Liu Xuemei
Published: November 2020

Due to the nonlinear characteristics of runoff data and the poor performance of the single prediction model, a weighted integrated modified complementary ensemble empirical mode decomposition (MCEEMD)-based model was proposed to predict the monthly runoff of three hydrological stations in the lower reaches of the Yellow River. In this model, particle swarm optimization (PSO) was used to optimize the parameters of support vector regression (SVR), back propagation neural network (BP), long short-term memory neural network (LSTM) that constitute it. The weight coefficients and frequency terms decomposed by MCEEMD were used to obtain the final prediction results. Results indicated that this model performs better than other models, with the Nash–Sutcliffe efficiency (NSE) reaching above 0.92, qualification rate (QR) reaching above 75% and all error indicators being minimal. In addition, considering the influence of extreme weather and climate anomalies, the integrated model combined the atmospheric circulation anomalies factors and the results can still be improved. It can be verified that this weighted integrated model can be used for the stable and accurate predication of medium- and long-term runoff.
Establishment and verification of the prediction model of soil wetting pattern size in vertical moistube irrigation
Authors: Fan Yanwei , Yang Zhiwei , Wei Hujun
Published: November 2020

To solve the difficulty of observing the soil wetting pattern of vertical moistube irrigation, the HYDRUS-2D software is used to simulate wetting pattern data under different conditions. Based on the analysis of Origin 9.0 and summarizing the law of simulation data, an empirical model for predicting wetting pattern size is constructed, with the reliability of the model verified by experimental data. The results show that the power function is used to fit the relationship between the size of wetting pattern and irrigation time. The power function exponent has small changes in three directions (vertical upward, horizontal, and vertical downward) of the moistube. Further analysis shows that the power function coefficient is in accordance with the power function relationship with soil-saturated hydraulic conductivity, the steady permeability of the moistube, and the difference between soil-saturated moisture content and initial moisture content. The average absolute error of statistical indicators of the built model is between 0.30 and 1.42 cm, the root mean square error is between 0.42 and 1.65 cm, and the Nash–Sutcliffe efficiency coefficient is not less than 0.93. The model has a good prediction effect and can provide a scientific basis for the design, operation, and management of the moistube irrigation engineering.
FermatS: A Novel Numerical Representation for Protein Sequence Comparison and DNA-binding Protein Identification
Authors: Zhang Yanping , Gao Ya , Ni Jianwei , Chen Pengcheng , Wang Xiaosheng
Published: November 2020

Aims:

Based on protein sequence information, a simple and effective method was used
to analyze protein sequence similarity and predict DNA-binding protein.

Background:

It is absolutely necessary that we generate computational methods of low complexity
to accurate infer protein structure, function, and evolution in the rapidly growing number of
molecular biology data available.

Objective:

It is important to generate novel computational algorithms for analyzing and comparing
protein sequences with the rapidly growing number of molecular biology data available.

Method:

Based on global and local position representation with the curves of Fermat spiral and
normalized moments of inertia of the curve of Fermat spiral, respectively, moreover, composition
of 20 amino acids to get the numerical characteristics of protein sequences.

Results:

It has been applied to analyze the similarity/dissimilarity of nine ND5 proteins, the
analysis results are consistent with the biological evolution theory. Furthermore, we employ the
Logistic regression with 5-fold cross-validation to establish the prediction of DNA-binding
proteins model, which outperformed the DNAbinder, iDNA-prot, DNA-prot and gDNA-prot by
0.0069-0.609 in terms of F-measure, 0.293-0.898 in terms of MCC in unbalanced dataset.

Conclusion:

These results show that our method, namely FermatS, is effective to compare,
recognition and prediction the protein sequences.
Anti-Cancer and Anti-Bacterial Effects of Terfezia boudieri-Derived Silver Nanoparticles
Authors: Yaghoubi Hashem , Izadpanah Amin , Nedaei Shahla , Akbari Hossein , Mikaeiliagah Elmira , Mostany Ricardo , Chandrasekar Bysani , Alt Eckhard , Izadpanah Reza
Published: November 2020

Background:

The use of nanoparticles has markedly increased in biomedical sciences.
The silver nanoparticles (AgNPs) have been investigated for their applicability to deliver
chemotherapeutic/antibacterial agents to treat cancer or infections disease. However, the existing
chemical and physical methods of synthesizing AgNPs are considered inefficient, expensive and toxic.

Methods:

Natural products have emerged as viable candidates for nanoparticle production,
including the use of Terfezia boudieri (T. boudieri), a member of the edible truffle family.
Accordingly, our goal was to synthesize AgNPs using an aqueous extract of T. boudieri (green
synthesized AgNPs). Since certain infectious agents are linked to cancer, we investigated their
potential as anti-cancer and antibacterial agents.

Results:

The synthesis of AgNPs was confirmed by the presence of an absorption peak at 450nm
by spectroscopy. The physico-chemical properties of green synthesized AgNPs were analyzed by
UV-Vis, FT-IR, XRD, SEM, and TEM. In addition, their potential to inhibit cancer cell
(proliferation and the growth of infectious bacteria were investigated.

Conclusion:

The size of nanoparticles ranged between 20-30nm. They exerted significant
cytotoxicity and bactericidal effects in a concentration and time-dependent manner compared to T.
boudieri extract alone. Interestingly, the synthesis of smaller AgNPs was correlated with longer
synthesis time and enhanced cytotoxic and bactericidal properties.
Anti-Ulcerogenic and Cytoprotective Effects of Saharian (Sidr) Honey from Algeria
Authors: Djebli Noureddine , Mustafa Mohammad Rais , Keskin Merve , Kolayli Sevgi
Published: November 2020

Aim and Objective:

This study aimed at investigating the gastro-protective effects of Algerian Sahara (Sidr) honey
from Apis mellifera intermissa against HCl/Ethanol-induced gastric ulcers in rats

Material and Methods:

Total phenolic content, antioxidant activity and phenolic compounds were determined. Than, Three
groups of rats (control, HCl/ Ethanol induced ulcer, and orally administered honey) were used for the determination of gastro
protective effect of Sidr honey.

Results:

Total phenolic content, total flavonoid content, and DPPH activity of the honey sample
were determined as 47.35±3.35 mg GAE/100 g, 2.13±0.17 mg QE/100 g, and 229.24±0.02
mg/mL, respectively. Oral pretreatment of rats with honey (1.2 g/Kg body weight orally at an
interval of 2 days) protected gastric mucosa against HCl/Ethanol-induced damage by decreasing
ulcer score, the volume and acidity of gastric juice and increasing pH.

Conclusion:

These results were confirmed by the histological assessment, which demonstrated a
significant gastro-protective activity of Saharian (Sidr) honey against HCl/Ethanol-induced
stomach ulcer. Plasma tumor necrosis factor-α, IL-6 and PGE2 were also measured. Sahara honey
significantly decreased the plasma TNF-α, PGE2, and IL-6 concentrations.
Synthesis, Characterization and Applications of Spinel Cobaltite Nanomaterials
Authors: Patel Ashok R. , Sereda Grigoriy , Banerjee Subhash
Published: November 2020

Recently, spinel structures (AB2O4) Nanoparticles (NPs) having binary and ternary mixtures
of metal oxides have been established as promising redox catalysts. Due to the presence of two mixed
valence metal cations, transport of electrons takes place easily between multiple transition-metal cations
with relatively low energy of activation. Among these, spinel cobaltite (MCo2O4) is very attractive
due to its low cost, non-toxicity, higher stability, higher electronic conductivity and electrochemical
property. To date, MCo2O4 has been used in the fabrication of supercapacitors, electrodes for oxygen
evolution reaction, and electrochemical sensors for glucose. A variety of MCo2O4materials have been
synthesized, characterized, and utilized in the fabrication of super capacitors, electrodes for oxygen
evolution reaction, and electrochemical sensors for glucose. The progress in the field of the spinel
MCo2O4 materials opens the door to novel and efficient applications in the nanoscience and nanotechnology,
and elctrochemistry.
A Review of Research Progress on Agathis dammara and its Application Prospects for Cardiovascular Diseases and Fatty Liver Disease
Authors: Wang Anyi , Yue Shanshan , Peng Ankang , Qi Rong
Published: November 2020

:

Cardiovascular diseases and fatty liver disease have become the leading causes of death in
modern society. However, the currently existing drugs do not solve all issues related to these diseases;
thus, it is expected that more potential drugs for clinical use will be developed. Undeniably, natural
products have attracted increasing attention. It is of great significance to identify effective active
monomer components for drug discovery and disease prevention. As a pure natural product, Agathis
dammara (AD) has antioxidant, hypolipidemic, hypoglycemic, antitumor, and anti-inflammatory activities.
However, at present, there are few reports regarding the effects of AD on chronic inflammatory
cardiovascular diseases, such as aneurysm, atherosclerosis, myocardial ischemia-reperfusion injury,
and cardiac hypertrophy and liver diseases such as fatty liver disease. AD and products derived from it
have a very broad application prospect for cardiovascular diseases and fatty liver disease.
Inflammation-based Scores are Associated with the Prognosis of Patients with Aneurysmal Subarachnoid Hemorrhage After Neuro-intervention
Authors: Yi Ho Jun , Lee Dong Hoon , Sung Jae Hoon
Published: November 2020

Objective:

Prognostic significance of inflammatory response has been reported in various
diseases. The objective of this study was to analyze the association between inflammation-
based scores and the prognosis of patients who underwent neuro-intervention for aneurysmal
subarachnoid hemorrhage (SAH).

Methods:

Inflammation-based scores such as neutrophil to lymphocyte ratio (NLR), lymphocyte to
monocyte ratio (LMR), and monocyte to high-density lipoprotein cholesterol (HDL-C) ratio
(MHR) were analyzed for aneurysmal SAH patients who underwent endovascular intervention. Unfavorable
functional outcome was defined as a modified Rankin Scale (mRS) score of 3-6. Receiver
operating characteristic (ROC) curve analysis was performed to identify cut-off values of inflammation-
based scores for predicting unfavorable functional outcome. Logistic regression analyses
were performed to explore the relationship between inflammation-based scores and the prognosis
of patients.

Results:

A total of 498 patients were enrolled. Optimal cutoff values of inflammation-based scores
of NLR, LMR, and MHR for unfavorable functional outcome were 5.7, 4.2, and 1.5, respectively
(p < 0.001, < 0.001, and 0.004, respectively). In multivariate analysis, NLR value ≥ 5.7 (odds ratio
[OR] 1.92, 95% CI 1.42–3.42; P = 0.008), LMR value < 4.2 (OR 1.74, 95% CI 1.48–2.98; P =
0.018), and MHR value ≥ 1.5 (OR 1.44, 95% CI 1.22–2.82; P = 0.040) were independently associated
with unfavorable functional outcome.

Conclusion:

Inflammation based scores were associated with functional outcome after endovascular
intervention for aneurysmal SAH. Higher NLR and MHR with lower LMR could predict unfavorable
outcomes of aneurysmal SAH patients who underwent endovascular intervention.
Molecular Processes Exploited as Drug Targets for Cancer Chemotherapy
Authors: Gupta Satya P. , Sharma Anjana , Patil Vaishali M.
Published: November 2020

Cancer is an uncontrolled malignant tumor growth taking place in any tissue of the body and attains
complex diversity which makes it difficult for oncologists to choose therapeutics. The changes leading to
formation of cancerous cells occur due to a series of molecular events. Now scientists are trying to understand the
various molecular processes that are involved in the growth of cancers. This article presents a brief account of
epigenetics with reference to DNA methylation and histone modification as an important contributor to the
formation of cancer cells. Drug targeting the epigenetic regulators has been considered for various types of
cancer. The enzymes in DNA methylation and histone modification, FDA approved clinical drugs along with the
challenges associated with the development of anti-cancer target based therapeutics are summarized.
Fournier’s Gangrene Due to Salmonella Typhimurium in a Healthy Male: A Rare Aberrant Infection
Authors: Gupta Varsha , Singhal Lipika , Pal Kritika , Bhushan Mani , Sharma Rajeev , Chander Jagdish
Published: November 2020

Introduction:

Human Salmonella infections have been classically distinguised into diseases caused by typhoidal
and non-typhoidal salmonella (NTS). Typhiodal salmonella includes S. enterica serovars Typhi and Paratyphi that cause the
systemic disease but are restricted to human infections, while NTS consists mainly of other serovars that predominantly
cause self-limiting gastroenteritis in humans. Localisation of foci with persisting infection occurs due to dissemination of the
bacteria throughout the body and can cause a variety of rare clinical syndromes at aberrant sites. Fournier’s gangrene, a rapidly progressive, often fatal, necrotizing fasciitis of the external genitalia and perineum due to Salmonella Typhimurium, is a
rare manifestation and has never been reported.

Case:

A 22-year-old male, apparently healthy patient with no relevant past medical history presented to surgical emergency
with chief complaints of swelling of bilateral scrotal area. Infective etiology was considered and a diagnosis of fournier’s
gangrene was made. Pure growth of Salmonella Typhimurium was obtained after repeated subculture and was identified biochemically and on serotyping, as Salmonella enterica serotype Typhimurium using specific antisera.

Conclusion:

In our case report, we describe a case of fournier’s gangrene due to Salmonella Typhimurium in an otherwise
healthy male to highlight the unusual presentation of Non typhoidal salmonellae at an aberrant site. We also emphasize the
importance of using selective media like Selenite F broth for isolation of Salmonella Typhimurium from a pus sample.
Psychological and Mental Health Issues During the SARS-CoV-2 Global Pandemic: A Critical Analysis
Authors: Khan Tahmeena , Azad Iqbal , Lawrence Alfred J.
Published: November 2020

Introduction:

With the outbreak of the SARS-CoV-2 in Wuhan, China in December,
2019, presently over 200 countries have been facing gruesome health effects of the deadly virus,
with cases and casualties on the rise. So far, no concrete medicinal drug or vaccine has been developed
to check the lethal viral infection, henceforth authorities have emphasized on practicing social
distancing and imposed strict lockdowns forcing people to confine in their homes.

Material and Methods:

This review was aimed to analyze the effects on mental health and well being
during the pandemic. The studies cited in the review were sourced from journals, books and digital
media reports. The research papers indexed in databases such as PUBMED, SCOPUS, INDEX
COPERNICUS, CHEMICAL AND BIOLOGICAL ABSTRACTS, MEDLINE, EMBASE, EBSCO,
DOAJ and THOMSON REUTERS were reviewed and have been included in the review.

Results:

The coronavirus mayhem has not only posed a threat to human health, but also jolted different
aspects of society, including mental and psychological health. Loss of freedom, boredom,
fear and angst are some of the mild psychological effects, whereas a rise in domestic violence and
suicidal tendencies is the more serious consequence reported from different parts of the world during
the lockdown period.

Conclusion:

This article is a comprehensive analysis of the effects on mental and psychological
well being during this critical time. Strategic measures to be adopted by individuals and administration
to cope up with the situation are also suggested as it should be an immediate priority to address
the overall distress caused by the pandemic in public.
Optimization of Production Activated Carbon for Removal of Pharmaceuticals Waste Using Taguchi Method and Grey Relational Analysis
Authors: Jatmiko Tri
Published: November 2020

The development of the pharmaceutical industry has led to increased environmental pollution by pharmaceutical waste. This encourages efforts to develop effective and inexpensive pharmaceutical waste management. One effort to handle pharmaceutical waste is to use activated carbon. In the manufacture of activated carbon there are several factors that affect the quality and performance of activated carbon produced. This research seeks to determine the optimum factors in making activated carbon and study its performance in adsorbing pharmaceutical waste. Multi-response analysis based on the Taguchi Grey relational analysis method is used to determine the optimum conditions. The most influential factors in the production of activated carbon, respectively, are pyrolysis temperature (800°C), ratio of precursors and activating agents (1:1), residence time (150 minutes) and finally the type of activator (KOH).
O protagonismo do banal e a performance nas bandas desenhadas documentais
Authors: Muanis Felipe
Published: November 2020

Este trabalho visa analisar estratégias da banda desenhada norte-americana dos anos 1960, em especial produzida por Robert Crumb e Harvey Pekar e rever a sua influência nos quadrinhos documentais contemporâneos, nos quais a autorreferencialidade e a banalidade se evidenciam como caraterísticas da banda desenhada moderna. A proposta é dialogar com a teoria da performance de Paula Sibilia, com a presença do homem comum nas mídias e, por fim, com os conceitos de “virada demótica” de Graeme Turner e de “democratainment” de John Hartley.
Televisualidade e a realidade dos média
Authors: Velhinho Ana
Published: November 2020

A viragem para o século XXI consolida a construção de uma televisualidade, trazida pela naturalização da presença dos meios de comunicação de massas no nosso quotidiano. A fronteira entre o que se pode ver, registar e partilhar no plano público da visualidade é tão ténue quanto controversa, apesar de convocar o cidadão comum para contribuir ativamente para o fluxo de mensagens e imagens que alimentam a rede global e fazem circular uma realidade extra-ecrã, sujeita a um conjunto de filtros e discursos, com acesso e difusão em tempo real. Quando se assiste ao emergir, no seio da ficção, de géneros reality, que operam uma comutação de códigos dirigidos ao consumo e ao espetáculo que caraterizam a hiperrealidade em que vivemos, rapidamente o voyeurismo e a violência passam a integrar os padrões de sociabilidade atuais, pautados pelo imediatismo e superficialidade preconizados pelos média. Estes regimes escópicos produzem no espetador uma relação dual com as imagens, que volatiza o seu papel e autoridade no plano da representação e da vida.
A corporeidade na contemporaneidade: algumas reflexões sobre o discurso publicitário
Authors: Santos Cristina
Published: November 2020

Com o presente artigo pretende-se refletir sobre a importância que a corporeidade tem na atualidade. Paralelamente, procura-se perceber qual o impacto que a emergente valorização do corpo belo e jovem, como propriedades características de uma imagem corporal que reflete os cânones estéticos vigentes, terá no discurso publicitário e qual o contributo que a publicidade poderá ter nessa estilização imagética prevalecente. Para o efeito, efetuou-se uma revisão da literatura, a qual permitiu detetar a particular preponderância da beleza corporal em contextos juvenis e femininos, dado o peculiar enfoque que a aparência assume para a juventude, com especial destaque junto das raparigas.
As potencialidades do estudo da imagem fotográfica na antropologia visual
Authors: Caldeira Sofia
Published: November 2020

Numa sociedade cada vez mais visual, torna-se compreensível que disciplinas como a antropologia tenham começado a manifestar um crescente interesse nas questões da visibilidade. Embora esta preocupação não seja exatamente recente, o problema de “O que fazer com a imagem?” tem sido fonte de constantes inquietações. Durante décadas, a antropologia visual continuou confinada a práticas tradicionalistas e limitativas, que viam as tecnologias visuais como meras ferramentas de pesquisa ou como modo de apresentar os seus estudos. Apesar disso, recentemente, abandonando a teimosia metodológica que limitava o estudo antropológico ao método malinowskiano, o estudo de imagens de variadas proveniências tem emergido como um campo válido para a imersão etnográfica, com o potencial de revelar processos percetuais, históricos e socioculturais.Das infindáveis formas de produção imagética, centro-me neste ensaio nas potencialidades trazidas pela análise da imagem fotográfica vernacular. Tal como a própria análise imagética, necessariamente multidisciplinar e multimetodológica, também este ensaio vive do cruzamento de textos e pontos de vista, vindos de várias disciplinas.O ensaio procura apontar algumas das potencialidades trazidas pelo uso de corpus imagéticos fotográficos, enfatizando as afinidades já existentes entre a atividade fotográfica e etnográfica. Do seu aparente caráter apodítico à sua visão necessariamente subjetiva, passando pela sua capacidade performativa – a fotografia tem o potencial de fornecer ao antropólogo material precioso para compreender, de modo não-intrusivo e da perspetiva do sujeito estudado, as mais variadas dinâmicas sociais.
Potencialidades da metodologia photovoice na intervenção com pessoas idosas institucionalizadas
Authors: Chaves Rosalinda
Published: November 2020

O envelhecimento tem sido assumido como vitória e desafio mundial, destacando-se como fenómeno contemporâneo de enorme pertinência. As instituições têm uma enorme responsabilidade na garantia do bem-estar e dignidade dos idosos, para que elas próprias não se tornem numa ameaça. É de enorme importância continuar a apostar-se num melhor entendimento dos fatores associados à realidade da institucionalização e continuar a fomentar a implementação de boas práticas neste género de cuidados, para que melhor se promova o bem-estar destas pessoas. Empregues em diversos campos do saber, as metodologias visuais têm vindo a afirmar- se como vias credíveis e legítimas de exploração da realidade social e cultural, estando o recurso a tecnologias e a linguagens artísticas a ser cada vez mais utilizado, nomeadamente com idosos. O Photovoice, metodologia de fotografia participativa desenvolvida e ampliada por Wang e Burris (1997), é um processo através do qual as pessoas identificam, representam e impulsionam a sua comunidade. Este artigo almeja refletir sobre o Photovoice enquanto forma de intervenção e pesquisa pelo bem-estar de idosos institucionalizados. Englobará uma análise do conceito na velhice, integrando- se a reflexão sobre a vantagem da utilização desta metodologia com tais populações.
Aspetos da afirmação da cultura visual em Portugal: o papel de António Ferro. Da Ilustração Portuguesa ao arquivo fotográfico do SPN
Authors: Baptista Paulo
Published: November 2020

Durante a década de 1920 e o início da de 1930 a cultura visual portuguesa sofreu uma profunda transformação, percetível nos magazines ilustrados de grande circulação. Um dos primeiros traços dessa mudança terá sido o da renovação da Ilustração Portuguesa, em 1921, com um novo diretor, António Ferro, apoiado pelo jornalista e consultor Leitão de Barros. Traziam um programa visual modernizado que viria a ter continuidade noutros magazines ilustrados e em particular, desde 1927, no Notícias Ilustrado, com um figurino visual cosmopolita, em linha com os magazines ilustrados internacionais.Foi Ferro que, em Portugal, se aventurou primeiro num género de jornalismo com recurso exaustivo à imagem, quer com imagens sugeridas pela sua escrita quer com o uso da fotografia, muitas vezes só com legenda, como sucedeu frequentemente no Notícias Ilustrado.Porventura o ponto mais alto do jornalismo “visual” de António Ferro terá sido a longa entrevista a Salazar, publicada no Diário de Notícias em 1932. O virtuosismo com que António Ferro soube ligar a escrita e a fotografia na construção de uma imagem para a figura praticamente “invisível” de Salazar, como sugeriu José Gil, ficou bem demonstrado, sendo inculcada num imaginário coletivo que, apesar de todas as mudanças políticas e dos anos volvidos, ainda subsiste, prova da força de uma propaganda visual assaz eficaz. Seria Ferro, já como diretor do Secretariado de Propaganda Nacional, em 1933 e, na sequência lógica desse percurso, a criar logo um arquivo fotográfico nesse departamento estatal, serviço que daria apoio à máquina de divulgação visual do regime até ao seu declínio.
Impressões de um passado incógnito. Dos vestígios da memória pessoal à memória histórica entre o século XIX e o século XX em Portugal
Authors: Velhinho Ana , Marques Cardoso Inês
Published: November 2020

O presente artigo tem como ponto de partida a investigação sobre a árvore genealógica de uma das autoras, impulsionada pelos relatos na primeira pessoa transmitidos por uma tia-avó. Tal transferência rica, embora difusa, de indícios de um passado que remonta ao início do século XX em Portugal, constituiu uma oportunidade para estender a recolha a outros antepassados a partir de variados tipos de arquivo. A esta memória oral, que exterioriza as emoções e factos numa mescla pessoal e afetivamente modelada, justapõem-se os registos materiais, visuais e documentais. Nestes incluem-se objetos nostálgicos, fotografias de família e registos paroquiais de batismos, casamentos e óbitos, provenientes de diversos arquivos distritais. O resgate de memórias dispersas, que até à data permaneceram na penumbra entre gerações, trouxe à tona eventos enigmáticos e significativos em Portugal. Tais como a migração e radicação em meados do século XIX de várias famílias espanholas de Badajoz na Amareleja, ou o terramoto de Benavente de 1909 presenciado pelos bisavós paternos de uma das autoras, documentado pelo fotógrafo Joshua Benoliel, fornecendo uma visão humanista e intimista sobre a catástrofe. Da reconstituição histórica, manifesta na teia de ligações entre fotografias e textos, motivada por imagens mentais que começam a recuperar a sua forma sugerida pelas pistas e achados coletados, esboçam-se narrativas simultâneas alicerçadas em evidências genealógicas, cronológicas e geográficas. Nesta oscilação entre a esfera pessoal e coletiva, alicerçada em metodologias do domínio da História e dos Estudos Visuais, procura-se refletir sobre as possibilidades de tangibilização da memória, as migrações entre diferentes locais e o que permanece de referência emocional do local de origem, como são transferidas entre gerações as memórias pessoais, como reconstituir memórias esparsas e como a partir de memórias pessoais é possível enquadrar uma memória coletiva.
Preservando a Memória das Pedras
Authors: Aluai Sampaio Hugo , M. S. Bettencourt Ana , Santos-Estévez Manuel , Moreira José , Cachetas Henrique , Barbosa Aléssia
Published: November 2020

Para as comunidades do passado o mundo “físico” seria entendido como cheio de propriedades significantes. No seguimento dos trabalhos de Ingold (2000), Bradley (2000, 2009), ou Scarre (2009), o que hoje vemos como material inerte seria considerada “viva”. Essa será a presente perspetiva de abordagem. Certos afloramentos naturais estão associados a lendas ou crenças muitas vezes ligadas a criaturas mágicas ou estranhas “habitando” no seu interior ou “vivendo” entre eles o que, em muitos casos, converge na determinação de um lugar com denominação. Tal como as pessoas, os afloramentos podem ser vistos como entidades que podem e fazem a diferença, atuando como agentes que corporizam significados e histórias (Tilley, 2002, 2004), consequentemente passados ao longo de gerações.Durante a Pré-História alguns afloramentos foram gravados com motivos; outros, pela sua forma peculiar ou estranha, formaram parte de mitos históricos e de folclore. Em ambos os casos os afloramentos funcionaram como contentores de memória.Pretende-se focar a importância da fotogrametria e do registo tridimensional deste tipo de património cultural (frequentemente em risco de destruição), mostrando o potencial desta ferramenta na inventariação e no estudo deste tipo de lugares de memória.Muitos casos de estudo apresentados foram objeto de análise em diferentes projetos, desenvolvidos de acordo com metodologias da Arqueologia e Antropologia Cultural aplicadas ao Noroeste da Ibéria.Este tipo de trabalho é fundamental tendo em conta a interpretação e o entendimento do papel dos afloramentos para as sociedades humanas e o seu contributo para a construção das paisagens pré-históricas e presentes.
Memórias de um militar e prisioneiro em Goa (1961-62)
Authors: Macedo Ana
Published: November 2020

Um militar de carreira, nos inícios de 1961, parte de Castelo Branco para Goa (Pangim) em cumprimento de uma comissão de serviço de dois anos como capitão de cavalaria. O objetivo da comissão em que se integra é o de mobilizar o Paquistão para a defesa dos territórios portugueses na Índia, reivindicados pela União Indiana desde 1950.Estas memórias são fruto da análise das dezenas de cartas que escreve ao pai durante o exercício da sua missão, bem como do diário que redige ao longo dos 5 meses em que é prisioneiro de guerra após a rendição das tropas portuguesas. Estamos certos de constituírem um contributo fiel e invulgar para a reconstituição do papel português em Goa após 450 anos de colonização.Sem as distorções que a distância temporal normalmente acarreta, os registos feitos diretamente pelo próprio permitiram-nos o acesso espontâneo aos hábitos e modos de vida goeses bem como à capacidade de adaptação do português e respetivas manifestações de interculturalidade. Permitiram-nos ainda aceder ao relato pormenorizado da vida quotidiana e dos sentimentos dos prisioneiros de guerra portugueses em Goa durante os meses de cativeiro.Perante o incumprimento das ordens de Salazar dirigidas ao governador Vassalo e Silva nos momentos que antecederam a invasão do território português na Índia – “Soldados vitoriosos ou mortos” – os ex-prisioneiros, regressados a Lisboa em maio de 1962, não foram, naturalmente ovacionados.