bluuebunny/crossref_metadata_2025 huggingface dataset:
Đề xuất cấu trúc cây phát hiện xung đột trong tập luật của tường lửa
Authors: Duy Nhất Vũ , Mạnh Hùng Nguyễn
Published: May 2019

Tường lửa là một thiết bị bảo mật mạng, trong đó sử dụng tập luật để kiểm soát các gói tin đi qua thiết bị. Cấu hình các luật tường lửa là nhiệm vụ rất khó khăn ngay cả đối với các chuyên gia bảo mật, đặc biệt đối với các hệ thống mạng phức tạp. Sai sót trong quá trình cấu hình thiết bị sẽ tác động tới hai khía cạnh: (i) làm ảnh hưởng tới sự an toàn của hệ thống mạng cần được bảo vệ và (ii) làm suy giảm năng lực xử lý của thiết bị tường lửa. Bài báo này đề xuất cấu trúc cây phát hiện xung đột (CDT: Conflict Detection Tree) có khả năng phát hiện tất cả các loại xung đột trong một tập luật của tường lửa một cách hiệu quả. Tính chính xác và tính hiệu quả của cấu trúc CDT được giới thiệu và chứng minh chi tiết trong bài báo. Cấu trúc CDT được triển khai và kiểm chứng với dữ liệu thực tế, cho thấy tính khả dụng của nó. DOI: 10.32913/rd-ict.vol3.no40.478
Phương pháp cải tiến LSTM dựa trên đặc trưng thống kê trong phát hiện DGA botnet
Authors: Hiếu Mạc Đình , Vạn Tống Văn , Tùng Bùi Trọng , Đức Trần Quang , Giang Nguyễn Linh
Published: May 2019

Phần lớn botnet sử dụng cơ chế sinh tên miền tự động (DGA: Domain Generation Algorithms) để kết nối và nhận lệnh từ máy chủ điều khiển. Việc tìm ra dạng DGA botnet thực hiện qua xác định cách thức tạo sinh tên miền đặc trưng cho loại botnet đó dựa trên những phân tích đặc trưng tên miền thu thập từ các truy vấn DNS. Trong bài báo này chúng tôi đề xuất phương pháp phân tích tên miền và phát hiện DGA botnet dựa trên sự kết hợp mạng LSTM (Long Short-Term Memory) với các đặc trưng thống kê như độ dài, entropy, mức độ ý nghĩa của tên miền nhằm tăng khả năng khái quát hóa cho mạng LSTM. Phương pháp đề xuất được thử nghiệm và đánh giá trên bộ dữ liệu tên miền thu thập trong thực tế bao gồm một triệu tên miền Alexa và hơn 750 nghìn tên miền được sinh bởi 37 loại DGA botnet. Kết quả thử nghiệm đã chứng minh tính hiệu quả của phương pháp đề xuất trong cả hai trường hợp phân loại hai lớp và phân loại đa lớp, với giá trị macro-averaging F1-score cao hơn 5% và nhận biết thêm được 3 loại DGA so với phương pháp phát hiện DGA botnet dựa trên mạng LSTM truyền thống. DOI: 10.32913/rd-ict.vol3.no40.528
Giấu tin thuận nghịch sử dụng các thuộc tính của ngữ cảnh dự báo để loại bỏ bản đồ định vị
Authors: Sao Nguyễn Kim , Tuấn Đỗ Văn , Ất Phạm Văn
Published: May 2019

Bài báo trình bày một lược đồ giấu tin thuận nghịch mới sử dụng phương pháp dự báo hình thoi. Các điểm ảnh được chia thành hai tập hợp: tập chấm và tập chéo. Tập chéo được sử dụng làm ngữ cảnh dự báo cho mỗi điểm của tập chấm. Tập chấm được dùng để nhúng tin theo phương pháp mở rộng sai số dự báo. Hai đại lượng có tính chất bất biến đối với quá trình nhúng là phương sai địa phương và độ sâu của ngữ cảnh dự báo trong miền giá trị dữ liệu ảnh (»0; 255… đối với ảnh đa mức xám) được sử dụng để sắp xếp các điểm ảnh của tập chấm. Kết quả nhận được là các đoạn khả mở (chứa toàn các điểm có thể mở rộng như ở trên). Mỗi đoạn khả mở được định vị bởi hai số nguyên có độ dài 16 bít. Dùng tối đa 10 đoạn có thể đủ để bao gồm hầu hết các điểm khả mở, tương đương 320 bít bổ trợ. Nhờ vậy, phương pháp đề xuất có thể cải thiện khả năng nhúng cũng như chất lượng ảnh do không cần dùng bản đồ định vị như các phương pháp trước đó. DOI: 10.32913/rd-ict.vol3.no40.598
Dung lượng bảo mật của hệ thống MIMO cỡ rất lớn khi có thiết bị nghe lén thụ động
Authors: Giang Vũ Lê Quỳnh , Kiên Trương Trung
Published: May 2019

Bảo mật ở lớp vật lý có thể kết hợp với các giải pháp bảo mật ở lớp trên để đảm bảo an ninh thông tin trong mạng thông tin vô tuyến. Các kết quả nghiên cứu trước đây đã chỉ ra rằng với điều kiện kênh truyền Rayleigh, việc sử dụng rất nhiều ăng-ten ở trạm gốc giúp hệ thống thông tin MIMO (Multiple-Input Multiple-Output) cỡ rất lớn tự được bảo mật trước thiết bị nghe lén thụ động. Tuy nhiên, bài báo này sau khi đề xuất các biểu thức dạng đóng cho dung lượng bảo mật cho hệ thống MIMO cỡ rất lớn trong điều kiện kênh truyền Rice có xem xét thành phần truyền tầm nhìn thẳng đã chứng minh được rằng thiết bị nghe lén thụ động có thể ảnh hưởng lớn đến dung lượng bảo mật của hệ thống. Các kết quả mô phỏng được cung cấp để kiểm chứng tính chính xác của các kết quả phân tích giải tích và để rút ra một số chỉ dẫn thiết kế quan trọng. DOI: 10.32913/rd-ict.vol3.no40.845
Caso 1/19: “E eu nunca fumei, doutor!”
Authors: Freitas Patrícia Luise Costa , Brandão Ana Carolina Rodrigues , Marins Leandro , Macedo Eduardo Felipe de Oliveira , Wagner Isabelle Ariane , Cubas Larissa , Fritzen Matheus , Pimentel Mariangela Pimentel , Steidle Leila John Marques
Published: May 2019

Caso relatado na Reunião de Discussão de Casos Clínicos do Hospital Universitário Prof. Polydoro Ernani de São Thiago, iniciada pelos Profs. Jorge Dias de Matos, Marisa Helena César Coral e Rosemeri Maurici da Silva, em julho de 2017. No dia 11 de abril de 2019, no bloco do curso de medicina, realizou-se a apresentação e discussão do caso cujo registro é apresentado a seguir: uma paciente de 54 anos vem à emergência com tosse, rinorréia e disfonia. Não é tabagista. Apesar da melhora dos sintomas com o tratamento, há imagem persistente no raio-x de tórax. Qual é o diagnóstico?
Effect of Corporate Social Responsibility and Good Corporate Governance on the Value of Company with Profitability as Moderating Variables
Authors: Yanto, S.E., Ak., M.Ak. Ery
Published: May 2019

This research aims to examine the influence of disclosure of corporate social responsibility and good corporate governance on the firm value to profitability as a moderating variable of manufactured companies listed on the Indonesia Stock Exchange for the period 2010-2012. This type of research is an association research using purposive sampling technique. The population in this study are the manufactured companies listed on Indonesia Stock Exchange during the years 2010-2012, as many as 91 companies as selected samples, thus, the total of observations in this study is composed of 273 companies that are analyzed using multiple linear regression with moderate regression analysis. The data used are from financial statements and sustainable report. Hypothesis testing using t test and F test. Research results showed that disclosure of corporate social responsibility and good corporate governance that is moderated affects firm value.
The Effect of Using Balanced Scorecard on Competitive Advantage and Its Impact on Firm Performance
Authors: Wati Lela Nurlaela , Triwiyono Gunawan
Published: May 2019

English Version

The paper is aimed to examine the effect of balanced scorecard on competitive advantage and its impact to firm performance. The samples of this research are companies that use balanced scorecard in DKI Jakarta as many as 50 companies. This research is uses primary data by giving questionnaires to corporate managers using balanced scorecard. We use Structural Equation Model with SmartPLS. The result of this research shows that there is positive effect between balanced scorecard to competitive advantage. Finding also shows that there is positive effect between balanced scorecard and competitive advantage to firm performance. The research also proves that there is positive effect between balanced scorecard to firm performance through competitive advantage. The findings of this study indicate that the better the application of balanced scorecard in the company will increase the competitive advantage and firm performance.
Dampak Earnings Management dalam Hubungan Kinerja dengan Cost of Debt (Studi Pada Perusahaan Manufaktur di Bursa Efek Indonesia)
Authors: Safiq Muhamad , Yustina Andi Ina , Muhaqiyah Aeniyatul
Published: May 2019

Penelitian ini bertujuan untuk menguji dampak earnings management dalam hubungan antara kinerja perusahaan dan cost of debt di Bursa Efek Indonesia (BEI). Dalam penelitian ini, kinerja perusahaan yang diproksi dengan rasio profitabilitas (return on equity), earnings management yang diukur dengan discretionary accrual, serta cost of debt diukur dengan rasio biaya bunga dibagi dengan rerata total utang. Sampel penelitian ini adalah perusahaan manufaktur yang terdapat di Bursa Efek Indonesia (BEI) tahun 2013 sampai dengan tahun 2015 yang diambil dengan menggunakan metode purposive sampling, menghasilkan 30 perusahaan manufaktur dan 90 observasi. Sehingga, data yang diperoleh berupa data panel. Selanjutnya, hasil observasi atau data yang diperoleh diproses dengan pengolah data Eviews. Hasil penelitian menunjukkan bahwa pertama, kinerja perusahaan berpengaruh negatif terhadap cost of debt; dan kedua, earnings management memoderasi (memperlemah) hubungan antara kinerja perusahaan dengan cost of debt. Untuk memperkuat hasil tersebut, penelitian selanjutnya dapat menambahkan jumlah perusahaan yang melalui periode yang digunakan dan industri yang berbeda.
Financial Ratio Analysis to Predict Financial Distress on Property and Real Estate Company listed in Indonesia Stock Exchange
Authors: Islami Imas Nurani , Rio William
Published: May 2019

This study aims to prove the ability of financial ratios in measuring financial distress. As is known that the start of the number of new companies that compete in order to achieve corporate goals, even more national companies that want to compete with foreign companies. On this basis, researchers attempt to prove the probability of occurring financial distress by using several financial ratios, especially large companies such as property and real estate firms. The financial ratios used in this study are current ratio, debt ratio, return on equity ratio, and capitalization ratio. With the type of research that is quantitative, the population that has been used in this study are property and real estate companies listed on the Indonesia Stock Exchange period 2012-2016. -. The sample obtained is a company that continuously publish its financial report within five years. According to the results of research that has been done, the ratio is able to measure the possibility of financial distress in property companies and real estate is the current ratio, debt ratio, and return on equity ratio. While the ratio is not able to measure the likelihood of occurrence of financial distress is capitalization ratio.
The Influence of Corporate Governance and Intellectual Capital towards Financial Distress (Empirical Study of Manufacturing Company in IDX for the Period of 2014-2016)
Authors: Fashhan Muhammad Rasil , Fitriana Vita Elisa
Published: May 2019

This study aims to test and find empirical evidence on the effects of corporate governance and intellectual capital on financial distress. In this study, the data sample used are manufacturing companies that publish their financial reporting in rupiah currency and listed in Indonesia Stock Exchange. Data collection method using purposive sampling and collected 249 samples from 2014-2016. The method of analysis used in this study is multiple regression analysis. The results of this study indicate that corporate governance does not have a significant effect on the financial distress of the company. While the relationship between intellectual capital and financial distress of the company showed a significant positive effect.
ANALISIS KEMAMPUAN AWAL LITERASI SAINS PADA MAHASISWA TINGKAT PERTAMA TERHADAP KONSEP BIOLOGI DASAR
Authors: Wibowo Agung
Published: May 2019

Penelitian bertujuan mendeskripsikan kemampuan awal literasi sains pada mahasiswa tingkat awal. Pengukuran kemampuan literasi sains yang disusun mengacu pada kompetensi Problem Solving dan Decision Making. Penelitian ini termasuk penelitian deskriptif kuantitatif. Penelitian dilakukan pada 15 mahasiswa jurusan S1 Pendidikan Biologi Institut Teknologi dan Sains Nahdlatul Ulama (ITSNU) Pasuruan. Instrumen penelitian menggunakan soal uraian berdasarkan skala literasi yang dikembangkan oleh Bybee (1997). Data hasil penelitian dikumpulkan dari hasil penskoran jawaban mahasiswa terhadap masalah yang diajukan secara tertulis. Hasil penelitian menunjukkan kemampuan literasi sains mahasiswa terhadap konsep biologi dasar untuk kedua kompetensi didominasi kategori nominal dengan rentang persentase 62%- 80%, sebagian kecil pada kategori fungsional sebesar 13% - 34 %. Pada kategori konseptual berada pada rentang 4% - 7% dan multidimensional sebesar 0%. Hasil yang diperoleh sesuai dengan penelitian sebelumnya yang menyatakan bahwa kemampuan literasi sains sebagian besar berada pada tingkatan rendah.
MANIPULATIVE DISCOURSE IN GEORGE ORWEL’S ANIMAL FARM
Authors: Basuki Edi Pujo
Published: May 2019

Animal Farm has been called George Orwell’s most ferocious propaganda (Voorhees, 1961 quoted in Jasim, M. H. and Aziz, Fatimah H). This novel is a satire referring to a communist regime persistently utilizing the kind of hypocritical propaganda merely for the purpose of keeping its totalitarian regime in power.. Animal Farm demonstrates more of such manipulative discourse, and this will be the focus of the study. The contribution of this study is that understanding manipulative discourse and its strategies gives a view of manipulative mechanism and thereby help people recognizing any hegemony form by those in power. The framework of the study applied Cognitive Pragmatics for Manipulative Discourse and Relevance Theory. The result of the study describes the characters that represent manipulative discourse as well as the types of the employed strategies (both global and local, both linguistic and non-linguistic ones). Manipulative discourses employed in the novel are produced or reproduced for two main general purposes. Firstly, the political discourses produced by Old Major is to convince all the animals of the necessity to fight against the human being for the freedom of the animals. The ideology exercised by the animals is anti-human ideology. Secondly, the manipulative discourses produced and reproduced by the pigs are to exercise their domination over the rest of the animals. The ideology of the pigs’ racism is exercised to gain more power, more privilege, and more access to the farm resources.
Investigation of Tribological Properties of Two-Component Bidisperse Epoxy-Polyester Composite Materials for Its Use in the Friction Units of Means of Sea Transport
Authors: Buketov Andriy , Brailo Mykola , Yakushchenko Serhii , Sapronov Oleksandr , Vynar Vasyl , Bezbakh Оleh , Negrutsa Roman
Published: May 2019

The tribological properties of complex polymeric materials, which include epoxy and polyester resins, two hardeners and two microdispersed fillers: mica-muscovite, copper (II) oxide, were investigated in the work. The results of the testing of specimens at dry friction and in the lubricant were analyzed. It is proved, that the antifriction properties of the composite depend on its composition, formation technology and testing conditions. It has been experimentally determined, that the material which was tested in the lubricating environment – Im = 0.25–0.30 mg/km, f = 0.03–0.04, differs with the improved indexes of wear rate and friction coefficient. As a result of the analysis of investigated microsurfaces studied by optical and electron microscopy, the phase heterogeneity of the composite material system was identified. It contributes to the reduction of the running-in distance of the specimen, and indicates the uniform distribution of the filler particles on the surface, has been found. The elemental composition of the compound was determined, which indicates the direct involvement of fillers in the process of friction. A change in the ratio of atoms on the specimen surface before and after the test was found. The results of the study of the surface in the phase contrast mode correlate with the results of the data obtained by electron microscopy.
Accelerating Convergence of Fluid Dynamics Simulations with Convolutional Neural Networks
Authors: Hajgató Gergely , Gyires-Tóth Bálint , Paál György
Published: May 2019

A novel technique to accelerate optimization-driven aerodynamic shape design is presented in the paper. The methodology of optimization-driven design is based on the automated evaluation of many similar shapes which are generated according to the output of an optimization algorithm. The vast amount of numerical simulations makes this process slow but the resource-intensive simulation part can be changed to so-called surrogate models or metamodels. However, there isn’t any guarantee of this solution’s accuracy.The motivation of this work was to develop an acceleration method to speedup optimization sessions without losing accuracy. Accordingly, the numerical simulation is kept in the pipeline but it is initialized with a velocity field that is close to the expected solution. This velocity field is generated by a predictive initializer that is based on a convolutional deep neural network. The network has to be trained before using it for initializing numerical simulations; the data generation, the training and the testing of the network are described in the paper as well.The performance of predictive initializing is presented through a test problem based on a deformable u-bend geometry. It has been found that the speedup in the convergence speed of the numerical simulation depends on the resolution of the predictive initializer and on the handling of velocities in the near-wall cells. A speedup of 13 % was achieved on a test set of 500 geometries that were not seen by the initializer before.
PHYSICO-CHEMICAL BASES OF ELECTROLYTIC SYNTHESIS OF CARBON NANOMATERIALS FROM MOLTEN SALTS. Part 1
Authors: Novoselova Inessa , Kuleshov Serhii
Published: May 2019

An analysis of the decomposition potentials of lithium, sodium, potassium, calcium, barium, and magnesium carbonates with different versions of cathode products (elemental carbon, carbon monoxide, metal and carbide) in the range of 300-1900 K showed that for K2CO3 deposition of alkali metal on the cathode is most energetically profitable process at all temperatures. For Na2CO3 it is possible to obtain carbon at T < 1000 K. With temperature increase, the predominant process is the reduction of alkali metal. For Li2CO3, CaCO3, BaCO3, MgCO3 at T < 950 °C carbon deposition will be more advantageous, at higher temperatures reduction up to CO will be more advantageous. The decomposition of CO2 flows at more positive potentials compared with carbonate systems. However, low activity of CO2 in carbonate-containing melts will prevent the significant contribution of this reaction to the electrode process. Thermodynamic calculations of the dependence of the carbon deposition potentials from carbonate anion on the acidity of the melt (concentration of oxide ions) show the possibility of displacing this potential up to 0.8 V by changing the acid-base properties of the melt. On the basis of the analysis of binary phase diagrams, Me–C and MeC–C, criteria for selecting the cathode material for generation of the tubular structure of graphite are established. The diagrams should contain: (1) – solid solutions of C–Me at a temperature of 700–900 °C and sufficient solubility of carbon (up to ~ 1 at.%) in the metal should be observed; (2) – after saturation of the solid solution with carbon, the precipitation (precipitation) of graphite from the metal should occur without the formation of intermediate carbide phases; (3) – in the case of the formation of carbides, the diffusion of carbon in the solid solution С–Ме and in the carbide phase MeС should flow with high speed and quickly reach the concentration of carbon saturation for graphite deposition.
MATERIALS BASED ON TITANIUM AND MANGANESE OXIDES FOR SELECTIVE RECOVERY OF LITHIUM FROM WATER SOURCES
Authors: Dzyazko Yuliya , Chaban Mariya , Bystryk Olga
Published: May 2019

Due to the ever-increasing production of electronic portable devices, including gadgets, lithium recovery is used to produce lithium-ion batteries. Lithium is electrochemically active, has the highest value of oxidation-reducing potential and the highest specific heat capacity among solid materials, making it a key element in the modern revolution of electric vehicles. The crust contains about 0.007% lithium, which is not in its pure form, but its insignificant concentrations are found in virtually all volcanic rocks and in the waters of mineral springs, sea water, and oceans. There are more than 20 minerals that contain lithium, but only few of them have content that is sufficient for commercial interest. A promising area is the processing of brines that are formed after desalination of seawater and mine waters. It is environmentally friendly and cost-effective. Since the concentration of lithium in such resources is low, sorption methods are advantageous compared to other. In this article materials that are widely studied in order to produce lithium-selective adsorbents are described. Most amphoteric oxides and hydroxides are amphoteric ion exchanges having both cation exchange and anion exchange properties. Such materials are of scientific interest in connection with the study of fission fragments behavior, release of radioactive isotopes, decontamination of sewage and concentration of microquantities of elements. The synthesis of such ion exchangers as amphoteric oxides and hydroxides is fairly simple and their cost per unit of capacity in most cases is much lower than the cost of organic resins. The combination of the material formed on the basis of hydrated titanium dioxide with known lithium manganese spinels allows to obtain a strong ion-exchange material for the selective extraction of lithium ions.
Penggabungan Metode MEC dan AHP dalam Penentuan Bantuan Rumah Tidak Layak Huni
Authors: Kuswandhie Rakhmad , Primadasa Yogi
Published: May 2019

Rumah tidak layak huni murapakan kondisi yang tidak ideal dimana bangunan tersebut tidak memenuhi persyaratan untuk dihuni. Kenyataannya rumah tidak layak huni sangat berhubungan dengan pemukiaman kumuh karena pada dasarnya didaerah permukiman kumuh tergambar kemiskinan masyarakat. Program Rehabilitasi atau bedah rumah tidak layak huni merupakan program yang diterapkan Pemerintah Kota Lubuklinggau untuk upaya meningkatkan rumah warga yang tidak layak huni yang ada di Kota Lubuklinggau menjadi layak huni. Permasalahan yang sering terjadi adalah proses penyeleksiaan masih bersifat subjektif, yang mana penyeleksian dilakukan dengan presepsi dari masing-masing anggota Dinas Sosial, belum juga mengingat banyaknya calon penerima yang akan menerima bantuan rehabilitasi rumah yang akan diseleksi dalam daerah tersebut, sehingga penyeleksi sangat merasa kesulitan dalam mengadakan penyeleksian bantuan ini. Dari permasalahan tersebut  Sistem Pendukung Keputusan merupakan alternatif untuk membantu Pemerintah Kota dalam penyeleksian penerimaan bantuan bedah rumah tidak layak huni. Dari data kandidat penerima bantuan beda rumah tidak layak huni  yang sudah di kumpulkan oleh Dinas Sosial ini akan di seleksi ulang di tambah kriteria-kriteria yang menjadi pendukung. Kriteria-kriteria seperti penghasilan,dinding rumah, lantai, jenis rumah, luas bangunan dan atap rumah ini digunakan untuk mendukung penelitian ini. Metode yang digunakan dalam penelitian ini dibantu dengan menggunakan penggabungan metode MEC dan AHP. Metode MEC digunakan untuk menentukan kriteria yang berpengaruh seperti  penghasilan, dinding rumah, lantai, jenis rumah, luas bangunan dan atap rumah. Metode AHP digunakan untuk menentukan bobot masing-masing kriteria.
Perancangan Arsitektur Sistem Digital Signage secara Terpusat pada Negara Berkembang
Authors: Yasirandi Rahmat , Rakhmatsyah Andrian , Alifudin Ridhwan
Published: May 2019

Banyak hal yang mendukung para stakeholder di Negara maju lebih beralih ke sistem digital signage untuk urusan signage, salah satu yang paling berperan adalah efisiensi. Efisiensi manajemen konten dan pendistribusian konten adalah salah satu yang utama yang dimunculkan. Dengan penyesuaian kebutuhan dan sumber daya, Negara berkembang juga dapat mengimplementasikan dan merasakan dampak manfaat dari sistem ini. Penelitian ini bertujuan untuk memberikan rancangan arsitektur sistem digital signage secara terpusat yang tepat untuk Negara berkembang. Dengan harapan bahwa sistem yang dikembangkan memiliki kemampuan layanan dan memiliki tujuan yang tetap sesuai dari sistem digital signage itu sendiri. Terbukti dengan hasil evaluasi terhadap sistem yang dibangun dapat membuktikan hipotesa H0 dan hipotesa H1. Menyatakan bahwa sistem yang dibangun tetap memiliki kemampuan skalabilitas dan performasi yang baik, dengan dapat dilihatnya hasil RTT di setiap DS Client bernilai 0,09 detik ketika jumlah DS Client mencapai 20 unit. Begitu juga pada hasil throughput di setiap DS client bernilai 5.9 Mbps ketika jumlah DS Client mencapai 20 unit. Dimana dengan nilai 5.9 Mbps tersebut, telah memenuhi kebutuhan minimum bandwith untuk memberikan layanan distribusi konten berupa video hingga 1080p.
Unsteady Flow Structures within a Turbine Rim Seal Cavity in the Presence of Purge Flow—An Experimental and Computational Unsteady Aerodynamics Investigation
Authors: Camci Cengiz , Averbach Michael , Town Jason
Published: May 2019

Flow within the space between the rotor and stator of a turbine disk, and an area referred to as the rim seal cavity, develops azimuthal velocity component from the rotor disk. The fluid within develops unsteady structures that move at a fraction of the rotor speed. A test is designed to measure the number of unsteady structures and the rotational speed at which they are moving in the rim seal cavity of an experimental research rig. Data manipulation was developed to extract the speed, and the numbers of structures present using two fast-response aerodynamic probes measuring static pressure on the surface of the nozzle guide vane (NGV)-side rim seal cavity. A computational study is done to compare measured results to a transient unsteady Reynolds-averaged Navier–Stokes (URANS). The computational simulation consists of eight vanes and ten blades, carefully picked to reduce the error caused by blade vane pitch mismatch and to allow for the structures to develop correctly, and the rim seal cavity to measure the speed and number of the structures. The experimental results found 15 structures moving at 77.5% of the rotor speed, and the computational study suggested 14.5 structures are moving at 81.7% rotor speed. The agreement represents the first known test of its kind in a large-scale turbine test rig and the first known “good” agreement between computational and experimental work.
Controlling Nuclear NF-κB Dynamics by β-TrCP—Insights from a Computational Model
Authors: Benary Uwe , Wolf Jana
Published: May 2019

The canonical nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway regulates central processes in mammalian cells and plays a fundamental role in the regulation of inflammation and immunity. Aberrant regulation of the activation of the transcription factor NF-κB is associated with severe diseases such as inflammatory bowel disease and arthritis. In the canonical pathway, the inhibitor IκB suppresses NF-κB’s transcriptional activity. NF-κB becomes active upon the degradation of IκB, a process that is, in turn, regulated by the β-transducin repeat-containing protein (β-TrCP). β-TrCP has therefore been proposed as a promising pharmacological target in the development of novel therapeutic approaches to control NF-κB’s activity in diseases. This study explores the extent to which β-TrCP affects the dynamics of nuclear NF-κB using a computational model of canonical NF-κB signaling. The analysis predicts that β-TrCP influences the steady-state concentration of nuclear NF-κB, as well as changes characteristic dynamic properties of nuclear NF-κB, such as fold-change and the duration of its response to pathway stimulation. The results suggest that the modulation of β-TrCP has a high potential to regulate the transcriptional activity of NF-κB.
Heterologous Immunity between Adenoviruses and Hepatitis C Virus (HCV): Recombinant Adenovirus Vaccine Vectors Containing Antigens from Unrelated Pathogens Induce Cross-Reactive Immunity Against HCV Antigens
Authors: Agrawal Babita , Gupta Nancy , Vedi Satish , Singh Shakti , Li Wen , Garg Saurabh , Li Jie , Kumar Rakesh
Published: May 2019

Host immune responses play an important role in the outcome of infection with hepatitis C virus (HCV). They can lead to viral clearance and a positive outcome, or progression and severity of chronic disease. Extensive research in the past >25 years into understanding the immune responses against HCV have still resulted in many unanswered questions implicating a role for unknown factors and events. In our earlier studies, we made a surprising discovery that peptides derived from structural and non-structural proteins of HCV have substantial amino acid sequence homologies with various proteins of adenoviruses and that immunizing mice with a non-replicating, non-recombinant adenovirus vector leads to induction of a robust cross-reactive cellular and humoral response against various HCV antigens. In this work, we further demonstrate antibody cross-reactivity between Ad and HCV in vivo. We also extend this observation to show that recombinant adenoviruses containing antigens from unrelated pathogens also possess the ability to induce cross-reactive immune responses against HCV antigens along with the induction of transgene antigen-specific immunity. This cross-reactive immunity can (a) accommodate the making of dual-pathogen vaccines, (b) play an important role in the natural course of HCV infection and (c) provide a plausible answer to many unexplained questions regarding immunity to HCV.
Regulation of Ribosomal Proteins on Viral Infection
Authors: Li Shuo
Published: May 2019

Ribosomal proteins (RPs), in conjunction with rRNA, are major components of ribosomes involved in the cellular process of protein biosynthesis, known as “translation”. The viruses, as the small infectious pathogens with limited genomes, must recruit a variety of host factors to survive and propagate, including RPs. At present, more and more information is available on the functional relationship between RPs and virus infection. This review focuses on advancements in my own understanding of critical roles of RPs in the life cycle of viruses. Various RPs interact with viral mRNA and proteins to participate in viral protein biosynthesis and regulate the replication and infection of virus in host cells. Most interactions are essential for viral translation and replication, which promote viral infection and accumulation, whereas the minority represents the defense signaling of host cells by activating immune pathway against virus. RPs provide a new platform for antiviral therapy development, however, at present, antiviral therapeutics with RPs involving in virus infection as targets is limited, and exploring antiviral strategy based on RPs will be the guides for further study.
Hematological Malignancy-Derived Small Extracellular Vesicles and Tumor Microenvironment: The Art of Turning Foes into Friends
Authors: Gargiulo Ernesto , Paggetti Jerome , Moussay Etienne
Published: May 2019

Small extracellular vesicles (small EVs) are commonly released by all cells, and are found in all body fluids. They are implicated in cell to cell short- and long-distance communication through the transfer of genetic material and proteins, as well as interactions between target cell membrane receptors and ligands anchored on small EV membrane. Beyond their canonical functions in healthy tissues, small EVs are strategically used by tumors to communicate with the cellular microenvironment and to establish a proper niche which would ultimately allow cancer cell proliferation, escape from the immune surveillance, and metastasis formation. In this review, we highlight the effects of hematological malignancy-derived small EVs on immune and stromal cells in the tumor microenvironment.
Gas Sensing with Nanoplasmonic Thin Films Composed of Nanoparticles (Au, Ag) Dispersed in a CuO Matrix
Authors: Proença Manuela , Rodrigues Marco S. , Borges Joel , Vaz Filipe
Published: May 2019

Magnetron sputtered nanocomposite thin films composed of monometallic Au and Ag, and bimetallic Au-Ag nanoparticles, dispersed in a CuO matrix, were prepared, characterized, and tested, which aimed to find suitable nano-plasmonic platforms capable of detecting the presence of gas molecules. The Localized Surface Plasmon Resonance phenomenon, LSPR, induced by the morphological changes of the nanoparticles (size, shape, and distribution), and promoted by the thermal annealing of the films, was used to tailor the sensitivity to the gas molecules. Results showed that the monometallic films, Au:CuO and Ag:CuO, present LSPR bands at ~719 and ~393 nm, respectively, while the bimetallic Au-Ag:CuO film has two LSPR bands, which suggests the presence of two noble metal phases. Through transmittance-LSPR measurements, the bimetallic films revealed to have the highest sensitivity to the refractive index changes, as well as high signal-to-noise ratios, respond consistently to the presence of a test gas.
Cavitation Erosion and Sliding Wear Mechanisms of AlTiN and TiAlN Films Deposited on Stainless Steel Substrate
Authors: Szala Mirosław , Walczak Mariusz , Pasierbiewicz Kamil , Kamiński Mariusz
Published: May 2019

The resistance to cavitation erosion and sliding wear of stainless steel grade AISI 304 can be improved by using physical vapor deposited (PVD) coatings. The aim of this study was to investigate the cavitation erosion and sliding wear mechanisms of magnetron-sputtered AlTiN and TiAlN films deposited with different contents of chemical elements onto a stainless steel SS304 substrate. The surface morphology and structure of samples were examined by optical profilometry, light optical microscopy (LOM) and scanning electron microscopy (SEM-EDS). Mechanical properties (hardness, elastic modulus) were tested using a nanoindentation tester. Adhesion of the deposited coatings was determined by the scratch test and Rockwell adhesion tests. Cavitation erosion tests were performed according to ASTM G32 (vibratory apparatus) in compliance with the stationary specimen procedure. Sliding wear tests were conducted with the use of a nano-tribo tester, i.e., ball-on-disc apparatus. Results demonstrate that the cavitation erosion mechanism of the TiAlN and AlTiN coatings rely on embrittlement, which can be attributed to fatigue processes causing film rupture and internal decohesion in flake spallation, and thus leading to coating detachment and substrate exposition. At moderate loads, the sliding wear of thin films takes the form of grooving, micro-scratching, micro-ploughing and smearing of the columnar grain top hills. Compared to the SS reference sample, the PVD films exhibit superior resistance to sliding wear and cavitation erosion.
Surface Plasmon Resonance (SPR) to Magneto-Optic SPR
Authors: Rizal Conrad , Belotelov Vladimir , Ignatyeva Daria , Zvezdin Anatoly K. , Pisana Simone
Published: May 2019

In this editorial, a brief background of the surface plasmon resonance (SPR) principle is discussed, followed by several aspects of magneto-optic SPR (MOSPR) and sensing schemes from the viewpoint of fundamental studies and potential technological applications. New sensitivity metrics are introduced that would allow researchers to compare the performance of SPR and MOSPR-based sensors. Merits of MOSPR over SPR based sensors and challenges faced by MOSPR sensors in terms of their practical use and portability are also considered. The editorial ends with potential new configurations and future prospects. This work is considered highly significant to device engineers, graduate and undergraduate students, and researchers of all levels involved in developing new classes of bio-devices for sensing, imaging, environmental monitoring, toxic gas detection, and surveying applications to name a few.
Floating Zone Growth of Sr Substituted Han Purple: Ba0.9Sr0.1CuSi2O6
Authors: Puphal Pascal , Allenspach Stephan , Rüegg Christian , Pomjakushina Ekaterina
Published: May 2019

We present a route to grow single crystals of Ba 0.9 Sr 0.1 CuSi 2 O 6 suitable for inelastic neutron studies via the floating zone technique. Neutron single crystal diffraction was utilized to check their bulk quality and orientation. Finally, the high quality of the grown crystals was proven by X-ray diffraction and magnetic susceptibility.
MODIS-Based Investigation of Flood Areas in Southern Cambodia from 2002–2013
Authors: Vichet Nguon , Kawamura Kensuke , Trong Dung Phan , On Nguyen Van , Gong Zhe , Lim Jihyun , Khom Sok , Bunly Chhun
Published: May 2019

In Cambodia and the Vietnamese Mekong Delta, floods commonly occur during the rainy season, and a better understanding of their spatio-temporal distribution is important for both disaster prevention and the improvement of agricultural production. This study investigated spatio-temporal flood inundation and land cover change from 2002 to 2013 in the southern part of Cambodia using Terra satellite on-board Moderate Resolution Imaging Spectroradiometer (MODIS) images. The algorithm for flood inundation detection, WFFI (Wavelet-based Filter for detecting spatio-temporal changes in Flood Inundation) was used, and the parameters were modified to fit the present study. The estimated inundation areas were validated using eight Landsat images. In a comparison between the original and modified WFFIs, the modified WFFI (70–96%) exhibited better accuracy than the original WFFI (30–70%). Overall, the temporal change in the flood inundation area presented a decreasing trend, and a link to the in-situ observed water level showed a decreasing trend during the rainy season. Furthermore, the estimated flood inundation exhibited a significant delay since 2008. Based on the yearly land cover MODIS product, the permanent water body and wetland areas decreased, whereas the cropland areas increased. This was as a result of increased agricultural productivity. However, water shortage was the major obstacle to increasing agricultural productivity, and it also had a negative impact on aquatic ecology, such as fish spawning grounds.
Quantum Mechanical and Optical Analogies in Surface Gravity Water Waves
Authors: Rozenman Georgi Gary , Fu Shenhe , Arie Ady , Shemer Lev
Published: May 2019

We present the theoretical models and review the most recent results of a class of experiments in the field of surface gravity waves. These experiments serve as demonstration of an analogy to a broad variety of phenomena in optics and quantum mechanics. In particular, experiments involving Airy water-wave packets were carried out. The Airy wave packets have attracted tremendous attention in optics and quantum mechanics owing to their unique properties, spanning from an ability to propagate along parabolic trajectories without spreading, and to accumulating a phase that scales with the cubic power of time. Non-dispersive Cosine-Gauss wave packets and self-similar Hermite-Gauss wave packets, also well known in the field of optics and quantum mechanics, were recently studied using surface gravity waves as well. These wave packets demonstrated self-healing properties in water wave pulses as well, preserving their width despite being dispersive. Finally, this new approach also allows to observe diffractive focusing from a temporal slit with finite width.
Indigenous Reflections on Identity, Trauma, and Healing: Navigating Belonging and Power
Authors: Urrieta Luis
Published: May 2019

Indigenous people are survivors of what some scholars have called the nexus of bio–psycho–social–cultural–spiritual intergenerational trauma. The effects of these multi-plex traumas brought on by European colonialism(s) reverberate into the present and affect Indigenous peoples at various scales, from local interpersonal relations to larger macro scales of geo-regional displacement. Indigenous peoples, however, have also survived the traumas of displacement, genocide, racism, surveillance, and incarceration by sustaining systems of ancestral and contemporary healing practices that contribute to individual and collective survivance. In this essay, I explore intergenerational rememberings of Indigenous identity, trauma, and healing based on personal, family, and community memory. Through rememberings, I seek to deconstruct the Western constructs of identity and trauma, arguing that these conceptions create trappings based on the exclusions of membership that support power hierarchies that perpetuate the dehumanization of Native peoples. By exposing these trappings, I will engage in my own decolonizing healing process by reclaiming, reconnecting, rewriting and rerighting histories. Finally, through an I/We Indigenous philosophy of belonging, I will argue that emotion can be an important saber (knowing) to help understand Indigenous identities as connected, collective, and ancestral ways of knowing and being that re/humanize Indigenous collective relational understandings.
Archeological Heritage in the Area of the Jewish Ghetto in Rome: Surveying and Reading Among Archetypes and Memories of the Past
Authors: Cennamo Gerardo Maria
Published: May 2019

This paper, part of a larger project of the Faculty of Should it be 00186Engineering of the International Telematic University UNINETTUNO (PRIN2010PEA4H8, Research Plan of National Interest, co-financed by the Italian Ministry for University Research), aims to provide documentation on the historical and archeological relevance of the Jewish Ghetto area in Rome, which is a site with numerous extraordinary features and memory traces of the past. The methodology adopted was mainly based on surveying activity—urban, architectural, and archeological—as well as the subsequent comparison of data obtained, investigating, and cataloging this tangible historical heritage and its relations with the archaeological heritage using the instruments of representation and surveying. Additionally, a different approach aimed at identifying a link between the subjective narration of the historical city and its objective description through the integration of digital methods of the cataloging and management of cultural heritage is applied.
Decomposing Income-Related Inequalities in Self-Reported Depression and Self-Rated Health Among Married Immigrants in South Korea
Authors: Hong Jihyung , Lee Jaehee
Published: May 2019

Health inequalities among immigrant minorities have been under-researched in South Korea. This study, therefore, measured the extent of income-related inequalities in self-reported depression and self-rated health (SRH) among married immigrants in South Korea and decomposed them into sociodemographic determinants using data from the 2015 National Survey of Multicultural Families (n = 15,231). The mean age of this sample was 37.8 years (SD = 10.8) and the mean duration of residence was 10.1 years (SD = 7.4). Eighty-five percent were female, and of these, 86.5% were from low/middle-income countries. Of these married immigrants, 34.6% reported experiences of depressive symptoms in the past year, and 9.5% reported their current health to be poor or very poor (weighted). The results also indicated substantial pro-rich health inequalities with the Erreygers concentration index of −0.1298 for self-reported depression and that of −0.1231 for poor SRH. Socioeconomic positions, reflected in income, subjective social status, and employment status, alongside satisfaction with a spouse, appeared to have much greater contributions to the overall inequality than demographics and type of migration. These findings suggest that social welfare policies and programmes can play important roles in reducing health inequalities that are ‘avoidable and unnecessary’ among married immigrants in South Korea.
Gain Adaptation in Sliding Mode Control Using Model Predictive Control and Disturbance Compensation with Application to Actuators
Authors: Haus Benedikt , Mercorelli Paolo , Aschemann Harald
Published: May 2019

In this contribution, a gain adaptation for sliding mode control (SMC) is proposed that uses both linear model predictive control (LMPC) and an estimator-based disturbance compensation. Its application is demonstrated with an electromagnetic actuator. The SMC is based on a second-order model of the electric actuator, a direct current (DC) drive, where the current dynamics and the dynamics of the motor angular velocity are addressed. The error dynamics of the SMC are stabilized by a moving horizon MPC and a Kalman filter (KF) that estimates a lumped disturbance variable. In the application under consideration, this lumped disturbance variable accounts for nonlinear friction as well as model uncertainty. Simulation results point out the benefits regarding a reduction of chattering and a high control accuracy.
Responsive ParaCEST Contrast Agents
Authors: Tóth Éva , Bonnet Célia S.
Published: May 2019

This article aimed at reviewing the advances on the development of paramagnetic complexes used as chemical exchange saturation transfer agents in magnetic resonance imaging. This relatively new type of contrast opens new avenues in the development of MRI probes for molecular imaging, and coordination chemistry lies at the center of such advances. Strategies to detect important biomarkers such as pH, cations, anions, metabolites, enzyme, and O2 were described. The current challenges, limitations, and opportunities in this field of research were discussed.
Case Study: A Practical Application of an Aerosol Treatment in a Commercial Mill
Authors: Scheff Deanna S. , Brabec Daniel , Campbell James F. , Arthur Frank H.
Published: May 2019

In recent years, there has been an increasing interest and need for alternatives to structural fumigations, and one alternative that has been used across the industry is aerosol insecticides. Previous tests inside a pilot-scale mill demonstrated that aerosol particle size, delivery method, and the spatial configuration of the mill all influenced effectiveness. However, there is no research conducted inside large commercial facilities. The objective of this research was to evaluate a pyrethrin-plus-methoprene aerosol application inside a commercial mill on adult Tribolium confusum Jacquelin duVal, confused flour beetle, directly exposed to the aerosol and residual effects on larvae. Additionally, five aerodynamic particle sizer spectrometers were placed in the facility and recorded instantaneous spray concentration and estimated aerosol deposition. Adult T. confusum exposed nearest to the aerosol application points had the highest percentage of affected adults (>60%). The aerosol also had vertical movement when released at the top of a three-story open room; instantaneous concentrations were recorded on the ground floor. The aerosol residual was highly effective after 6-weeks post aerosol exposure, as 80% of the bioassays did not have any adult emergence from exposed larvae. This research demonstrates a practical use of aerosol insecticides and their potential to be an effective alternative to structural fumigations.
Examination and Modification of Multi-Factor Model in Explaining Stock Excess Return with Hybrid Approach in Empirical Study of Chinese Stock Market
Authors: Huang Jian , Liu Huazhang
Published: May 2019

To search significant variables which can illustrate the abnormal return of stock price, this research is generally based on the Fama-French five-factor model to develop a multi-factor model. We evaluated the existing factors in the empirical study of Chinese stock market and examined for new factors to extend the model by OLS and ridge regression model. With data from 2007 to 2018, the regression analysis was conducted on 1097 stocks separately in the market with computer simulation based on Python. Moreover, we conducted research on factor cyclical pattern via chi-square test and developed a corresponding trading strategy with trend analysis. For the results, we found that except market risk premium, each industry corresponds differently to the rest of six risk factors. The factor cyclical pattern can be used to predict the direction of seven risk factors and a simple moving average approach based on the relationships between risk factors and each industry was conducted in back-test which suggested that SMB (size premium), CMA (investment growth premium), CRMHL (momentum premium), and AMLH (asset turnover premium) can gain positive return.