bluuebunny/crossref_metadata_2025 huggingface dataset:
Addressing Public Speaking Anxiety in Multicultural Counselling: The Use of Cognitive-Behavioural Therapy for International Students
Authors: Anwar Moh. Khoerul , Haq Muhammad Izzul , Salma Diafi , Wang Zhongjun
Published: August 2022

Abstract: Several studies have highlighted the importance of Cognitive Behavioural Therapy (CBT) in reducing public speaking anxiety. The studies also denote the increase of confidence by strengthening self-efficacy. This study explores previous studies that uncover the use of CBT in dealing with public anxiety to identify its potential as part of multicultural counseling for international students in higher education. International students have different academic and learning cultures, as well as social environments, affecting the development of certain anxiety in dealing with pressures to adapt to new environments. Therefore, it positions the investigation of CBT’s ability to reduce public speaking anxiety for international students as highly essential. This study contends that CBT is a useful technique to unpack irrational fear of speaking in public and promote self-efficacy, developing confidence and leading to good mental health. However, given the nature of targeted intervention are international students, multicultural counseling competencies are undoubtedly required for the therapy.
Abstrak: Beberapa penelitian telah menyoroti pentingnya Terapi Perilaku Kognitif (CBT) dalam mengurangi kecemasan berbicara di depan umum. Studi ini menunjukkan adanya peningkatan kepercayaan diri dengan memperkuat efikasi diri. Studi ini juga mengeksplorasi studi sebelumnya yang mengungkap penggunaan CBT dalam menangani kecemasan publik untuk mengidentifikasi potensinya sebagai bagian dari konseling multikultural untuk mahasiswa internasional di pendidikan tinggi. Mahasiswa internasional memiliki budaya akademik, pembelajaran, dan lingkungan sosial yang berbeda, yang semuanya memengaruhi perkembangan kecemasan tertentu dalam menghadapi tekanan untuk beradaptasi dengan lingkungan baru. Oleh karena itu, penelitian tentang CBT untuk mengurangi kecemasan berbicara di depan umum bagi mahasiswa internasional sangat penting. Studi ini berpendapat bahwa CBT adalah teknik yang berguna untuk membongkar ketakutan irasional berbicara di depan umum dan mempromosikan efikasi diri, mengembangkan kepercayaan diri dan mengarahkan kesehatan mental yang baik. Namun, mengingat sifat intervensi yang ditargetkan adalah siswa internasional, kompetensi konseling multikultural tidak diragukan lagi diperlukan dalam terapi.
Evaluation of Classical Guidance Programs During the Covid-19 Pandemic at Junior High School: Discrepancy Model
Authors: Nurrofifah Hani , Farozin Muh. , Mutiara Asfarina
Published: August 2022

Abstract: Guidance and counseling programs are designed to improve education. These programs continue to evolve, especially the classical guidance programs that require adaptation to the current Covid-19 pandemic education system. However, due to a lack of planning, the development and implementation of the classical guidance program in state junior high schools during the Covid-19 pandemic have not been optimal. Thus, this study identifies the performance of the classical guidance program at state junior high schools during the Covid-19 pandemic, using predetermined standards. This study used program evaluation standards and criteria from the Guidelines for Performance-Based Professional School Counselor Evaluation. The guidelines highlight that professional school counselors should carry out classical guidance services using effective learning strategies and classroom management techniques for all counselees based on their needs. These standards and criteria were then formulated into three components to determine the success of the classical guidance program, namely planning, implementing, and evaluating the classical guidance program. The analysis of the evaluation results showed that the classical guidance program during the Covid-19 had not met the standard.
Abstrak: Program bimbingan dan konseling dirancang untuk meningkatkan pendidikan. Program bimbingan dan konseling terus berkembang, terutama program bimbingan klasikal yang membutuhkan adaptasi dengan sistem pendidikan pada pandemi Covid-19. Meskipun demikian, perencanaan, pengembangan dan pelaksanaan program bimbingan klasikal di sekolah menengah pertama selama pandemi Covid-19 belum berjalan dengan optimal. Penelitian ini bertujuan mengidentifikasi kinerja program bimbingan klasikal di sekolah menengah pertama negeri selama pandemi Covid-19 menggunakan standar yang telah ditentukan. Standar dan kriteria evaluasi program yang digunakan adalah Guidelines Performance-Based Professional School Counselor Evaluation. Pedoman tersebut menyoroti bahwa konselor sekolah profesional harus melaksanakan layanan bimbingan klasikal dengan menggunakan strategi pembelajaran yang efektif dan teknik pengelolaan kelas untuk semua konseli berdasarkan kebutuhannya. Standar dan kriteria ini kemudian dirumuskan menjadi tiga komponen untuk menentukan keberhasilan program bimbingan klasikal, yaitu perencanaan, pelaksanaan, dan evaluasi program bimbingan klasikal. Analisis hasil evaluasi menunjukkan bahwa program bimbingan klasikal selama Covid-19 belum memenuhi standar.
La obligación política como obligación prudencial en el pensamiento filosófico político de Thomas Hobbes
Authors: Jaramillo Rojas Carlos Alberto
Published: August 2022

In Leviathan, Thomas Hobbes’ best-known work, the obligation to obey the state assumes a rational or prudential character because of the philosophical and epistemological theories from which this thinker has conceived the human nature. Those principles are related to a mechanical vision of the world in which the obedience to the sovereign is explained only as a need to conserve the life motion.According to Hobbes’ view, transcendental values do not exist as a moral foundation like in Aristothelic-Tomist School, neither categorical imperative like in Kantian ethics; only the passions and the universal motion principle constitute the elements which make possible the logic of the political obligation in his theory.
Desempeño del almidón natural de plátano, en el control de propiedades físicas en un fluido de perforación polimérico a nivel de laboratorio
Authors: Aguirre-Mogollón Alexandra , Ortiz-Romero Juan David , Tovar-Moreno Jorge Andres
Published: August 2022

Los fluidos de perforación poliméricos son uno de los productos más utilizados en la industria del petróleo, sin embargo, los aditivos usados para este lodo como el PAC-L y PAC-R eleva el costo de formulación. Se busca evaluar el desempeño del almidón de plátano en el control de las propiedades físicas como reología, lubricidad y filtrado. Para esto se obtuvo almidón a partir de la síntesis de la cascara de plátano, se diseñó un fluido base con el objetivo de compararlo con otros 10 fluidos de perforación en los cuales se usó almidón de plátano como sustituyente de los aditivos PAC-L y PAC-R a diferentes concentraciones. Se realizaron pruebas de reología, lubricidad y filtrado. A partir de esto se determinó la concentración óptima de almidón que se debe usar para obtener un fluido de perforación semejante al lodo base de estudio. La concentración de almidón de plátano que mantiene propiedades con el fluido en estudio (Filtrado API, Viscosidad Plástica, Punto cedente, Geles y lubricidad) es del 5,5% de almidón de plátano. Esta concentración se escogió con las pruebas más relevantes entre las mencionadas anteriormente porque aseguran un adecuado rendimiento del fluido de perforación, que permite alcanzar buenas características reológicas y tixotrópicas con las cuales se evitan problemas operativos como la pérdida del lodo, daño de formación, pega de tubería, sobrecalentamiento en la sarta, entre otros. Estos resultados nos confirman que el almidón de plátano “macho” puede reemplazar el PAC-L, PAC-R y la goma Xantica, siendo viable técnicamente para el uso de este aditivo en operaciones en campo. Así mismo, puede llegar a ser viable económicamente; por esta razón se recomienda hacer un análisis financiero que ayude a confirmar todas las variables estudiadas en un proyecto de investigación y que así sea factible tanto a nivel técnico como económico.
Evaluation of Growth Indices and Nutritional Status in Children Hospitalized at the Pediatric Ward of Shahid Sadoughi Hospital in Yazd, Iran in 2020
Authors: Edalatkhah Rohollah , Karimi Mehran , Parand Maryam , Aflatonian Majid
Published: August 2022

Background: Malnutrition is one of the most important health issues especially in developing countries that can have adverse effects on physical and mental health of children, resulting in various infections. This study aims to evaluate the growth indices and nutritional status in children hospitalized at the pediatric ward of Shahid Sadoughi Hospital in Yazd, Iran in 2020.
Methods: In this cross-sectional and descriptive-analytical study, the anthropometric indices of 100 children older than 1 month hospitalized in the pediatric ward of Shahid Sadoughi Hospital in Yazd, Iran in 2020 were determined. Children's information, including age, sex, cause of hospitalization, and duration of hospitalization were extracted from the patients' medical files and recorded in a checklist. Nutritional status was assessed using weight-for-age, weight-for-height, and height-for-age criteria.
Results: The prevalence of malnutrition among the studied children was 40% (18% acute malnutrition and 22% chronic malnutrition). The prevalence of wasting, underweight, and stunting status were 28%, 27%, and 20%, respectively. There was no significant difference in the malnutrition frequency and also the malnutrition type based on sex, age, cause of hospitalization, and duration of hospitalization (P > 0.05); however, the type of malnutrition was significantly associated with age (P < 0.05).
Conclusion: Considering the high prevalence of malnutrition in this study and the fact that malnutrition can lead to infections and increase the chances of hospitalization, it is recommended that all hospitalized children be evaluated and treated for malnutrition using anthropometric criteria and nutritional classifications.
Incidence of Overweight and Its Predictors in Adults after 10 Years of Follow-up: Yazd Healthy Heart Project
Authors: Moghtaderi Fatemeh , Sarebanhassanabadi Mohammadtaghi , Hosseini Shabnam , Pakseresht Mohammadreza , Beiki Omid , Seyed Hosseini Seyed Mostafa , Namayandeh Seyedeh Mahdieh , Emami Mahmood , Salehi-Abargouei Amin
Published: August 2022

Background: Obesity and overweight are important public health problems which are rapidly growing throughout the world. This study aims to provide 10-year incidence estimates of obesity and overweight in adults along with their risk factors in an Iranian adult population.
Methods: This cohort study was conducted within the framework of the Yazd Healthy Heart Project (YHHP) throughout phases from 2005-2006 to 2015-2016 among urban adult population. The participants comprised of 1000 males and 1000 females aged 20-74 years from urban areas of Yazd. Cox proportional hazards model was used to examine the potential risk factors for obesity and overweight.
Results: A total of 2000 participants aged 47.09 ± 16.97 years and body mass index (BMI) of 21.99 ± 2.21 kg/m2 were entered in this study at baseline. After 10 years of follow-up, the cumulative incidence of overweight for the entire population was 38.6% (41.6% in women and 36.8% in men). Furthermore, the 10-year cumulative incidence of obesity was 14.8% in the population (20.8% for women and 10.5% for men). Female participants showed a significantly higher incidence rate compared to males either for obesity or overweight. Regarding risk factors, there was a significant association between non-smoking (HR= 1.54, 95% CI: 1.06-2.25), socio-economic status (HR= 1.82, 95% CI: 1.13-2.94), and education (HR= 1.56, 95% CI: 1.14-2.13) with overweight (P < 0.05).
Conclusion: This study revealed the incidence rate of obesity and overweight is significantly high in adult population of Yazd, Iran especially in women. The most important predictors of overweight seem to be smoking, lower socio-economic status, and education.
The relationship of platelet to lymphocyte ratio with the presence and extent of coronary atherosclerosis detected by coronary computed tomography angiography
Authors: ÇAKIR Hakan , TOPRAK Cüneyt , KARAGOZ Ali , UYSAL Samet , HAVAN Nuri , KUZEYTEMİZ Mustafa , KAYMAZ Cihangir , DEMİR Mehmet
Published: August 2022

Objectives: Platelet-lymphocyte ratio (PLR) combines the predictive risk of platelet and lymphocyte counts into a single risk index. PLR has been studied as a predictive marker in a variety of cardiovascular diseases. However, our understanding of the link between PLR and coronary artery disease (CAD) remains limited. The present study aimed to evaluate the relationship between PLR and intensity of coronary atherosclerosis in patients with suspected CAD.
Methods: In this retrospective study, we included 221 patients undergoing dual-source 64-slice coronary computed tomography angiography (CCTA). Total and different types of leukocyte counts were measured with an automatic blood counter. Based on a modified version of the American Heart Association's categorisation, the coronary artery tree was divided into 16 segments. To assess the extent of coronary atherosclerosis, the number of affected coronary segments was counted. Coronary artery plaques were classified into three categories: (1) calcified plaque, (2) non-calcified plaque, and (3) mixed plaque.
Results: After multivariable backward stepwise regression analysis, PLR remained as an independent predictor for both the presence and extent of coronary atherosclerosis (OR=2.38, 95% CI: 1.27-4.47 and OR=1.66, 95% CI: 1.10-2.51, respectively). There was no significant relationship between PLR and plaque morphology.
Conclusions: Higher PLR was associated with the intensity of coronary atherosclerosis detected by CCTA. Further research is necessary to determine the optimal approach to using PLR in medical practice.
IMPROVING ENGLISH SPEAKING SKILLS THROUGH SMALL GROUP DISCUSSION
Authors: Susanti Lina , Mustofa Mutmainnah , Fatimatus Zahroh Fatimatus Zahroh
Published: August 2022

This research is aimed at inquiring the use of small group discussions in the improvement of speaking skills studied in classroom action research (CAR). The population of the research was the eighth-grade students of SMPN 2 Curug consist of thirty students. The researchers used one class as a control group. Based the result of this study, the researchers implemented the action in two cycles; every cycle consists of planning, acting, observing and reflecting. The first is planning, the researchers identified a problem. The second is acting, the researchers collected and analysed the data. The third is observing, in this stage the researchers developed a plan to make change and implemented these changes. This cycle reflects the components of action research. It is critical to consider the impact of the changes made when reflecting. The result of this research is the mean score of students on the speaking test before carrying out the Class Action Research (CAR) is 57,5 for pretest and post-test 64,7 in the first cycle, this is the student’s treatment. And in the second cycle 70,6 after using small group discussion. It means that the mean score of the post test is greater than the pre-test. Thus, this research that using small group discussion can improve students’ speaking ability for the eighth-year students of SMPN 2 Curug.
Diagnóstico energético en la Universidad Nacional de Santiago del Estero, Argentina
Authors: Giuliano Gabriela , Ortega Matías , Garzón Beatriz
Published: August 2022

Se exponen los resultados de un diagnóstico energético, realizado en la Facultad de Ciencias Exactas y Tecnologías de la Universidad Nacional de Santiago del Estero, Argentina. El objetivo es analizar los desempeños energéticos y realizar propuestas para una mayor eficiencia energética edilicia. La metodología consta de tres fases: 1) Relevamiento de datos, 2) Evaluación térmicoenergética y 3) Identificación y cálculo de medidas de mejoras de eficiencia energética de los edificios. El análisis evidencia un consumo eléctrico elevado, donde un 64% corresponde a refrescamiento de ambientes, el 22% a iluminación y 14% equipos varios. Posteriormente, se observa la disminución con la aplicación de un programa de sustentabilidad edilicia universitaria. A raíz de las mejoras propuestas, se concluye que el índice de eficiencia energética disminuye en un 17% en una primera etapa y se plantea que es posible llegar hasta un 38%, continuando con la implementación de mejoras mediante un plan de gestión integral para el ahorro y la eficiencia energética, con el fin de disminuir el impacto ambiental universitario.
Risk Factors of Syphilis and HIV/AIDS Coinfection
Authors: Yuindartanto Andre , Hidayati Afif Nurul , Indramaya Diah Mira , Listiawan M. Yulianto , Ervianti Evy , Damayanti Damayanti
Published: August 2022

Background: Syphilis infection and HIV are major health problems worldwide. Both of these diseases can be transmitted through sexual contact, so often a person suffers from both diseases at the same time. Purpose: To describe the risk factors of syphilis and HIV/AIDS coinfection in the Infectious Disease Intermediate Treatment Unit (UPIPI) inpatient and outpatient ward of Dr. Soetomo General Academic Hospital in 2019. Methods: The study design used in this study is a retrospective descriptive study aimed at evaluating sexual and non-sexual factors that cause syphilis and HIV coinfection. The research population was patients in the inpatient and outpatient rooms of UPIPI RSUD Dr. Soetomo Surabaya for the January-December 2019 period. The sampling technique was sourced from secondary data, namely medical record data from the inpatient and outpatient rooms of UPIPI RSUD Dr. Soetomo Surabaya for the period January-December 2019. The data in this study were obtained from medical records and patient biodata. Result: Based on the calculation results, it is known that age group (P=0.022>0.05), and gender (P=0.024>0.05) had no effect on the risk of syphilis and HIV coinfection, while marital status (P=0.048<0.05), sexual orientation (P=0.048<0.05), transmission model (P=0.044<0.05), and type of work (P=0.046<0.05fected the risk of syphilis and HIV coinfection. Conclusion: People with HIV/AIDS are expected to be active in participating in programs that are needed by patients, such as antiretroviral (ARV) therapy assistance programs and counseling that will prolong the quality of life in various aspects of life, both physical, psychological and social aspects.
Dermoscopic Examination in Malassezia folliculitis
Authors: Ahmad Zahruddin , Ervianti Evy
Published: August 2022

Background: Malassezia folliculitis (MF) is the most common fungal folliculitis, and it is caused by yeast of the genus Malassezia. MF may be difficult to be distinguished clinically from acne and other types of folliculitis, causing misdiagnosis and improper treatment. Dermoscopy has been very useful to support the diagnosis of several types of folliculitis, including MF. Purpose: To know the role of dermoscopic examination in MF. Review: The diagnosis of MF can be identified by usual clinical presentation with direct microscopy and culture of the specimen, Wood's light examination, histopathological examination, and rapid efficacy of oral antifungal treatments. Several studies reported that dermoscopy provides a deeper level of the image that links the clinical morphology and the underlying histopathology. Some dermoscopic patterns are observed consistently with certain diseases, including MF, so these could be used for establishing their diagnosis. The dermoscopic features of MF seem to correlate with the current understanding of its etiopathogenesis. Conclusion: Dermoscopic examination in MF will reveal dermoscopic patterns including folliculocentric papule and pustules with surrounding erythema, dirty white perilesional scales, coiled/looped hairs with perifollicular erythema and scaling, hypopigmentation of involved hair follicles, and dotted vessels.
Clinical and Cure Profile of Tinea Capitis Patients
Authors: Noviannisa Farah Ayu , Astari Linda , Alimsardjono Lindawati
Published: August 2022

Background: Tinea capitis (TC) is a superficial mycoses infection of hair follicles and hair shaft caused by dermatophytes of the genus Trichophyton and Microsporum. Tinea capitis can cause hair loss and scales with varying degrees of inflammatory response. The incidence varies depending on geographical location and factors that affect the incidence rate. It is important to know the incidence also the clinical and cure profile of tinea capitis to provide benefits in the prevention, diagnosis, and treatment. Purpose: To evaluate the clinical and cure profile of TC patients at the Dermatology and Venereology Outpatient Clinic of Dr. Soetomo General Academic Hospital Surabaya from January 2019 to January 2020. Methods: A retrospective descriptive study based on medical records with a total sampling technique. Result: Of the 10 TC patients, who were the research subjects, TC predominantly affected males and at 5–11 years age group. The highest risk factor was a history of contact with cats. Scales were the most common clinical feature. Microsporum canis was the most common causative species, ectothrix arthrospores was revealed during the direct microscopic examination, Wood lamp's fluorescence was mostly yellow-green, and cigarette-shaped hair was the most common dermoscopic finding. Eighty percent of subjects were diagnosed with gray patch type. Conclusion: The diagnosis of TC was established based on the patient's history, clinical examination, and supporting examination.
Hand Eczema in Nurses in COVID-19 Treatment Room: Frequency of Handwashing, Hand Sanitizer, Moisturizer, and Duration of Latex Gloves Use
Authors: Rosmarwati Ervina , Widhiati Suci , Novriana Dita Eka , Rahma Alfina , Kariosentono Harijono , Irawanto Muhammad Eko , Kusumawardani Arie , Ellistasari Endra Yustin , Oktavriana Triasari
Published: August 2022

Background: The COVID-19 pandemic causes health workers to use level 2 and level 3 personal protective equipment. Hand washing and the use of latex gloves are important in limiting the spread of COVID-19, but they can potentially induce hand eczema and skin pH disturbance if used too frequently. Purpose: Determine the correlation between the frequency of handwashing and duration of using hand sanitizer and moisturizer as well as skin pH level on the incidence of hand eczema in nurses in the COVID-19 treatment room at RSUD Dr. Moewardi Surakarta. Methods: This cross-sectional study was conducted in the COVID-19 treatment room at RSUD Dr. Moewardi Surakarta with 90 nurses as subjects. A validated questionnaire carried out the frequency of handwashing, hand sanitizer, moisturizer, duration of using latex gloves, and hand eczema complaints. The subject’s pH assessment was conducted after 4-5 hours in the COVID-19 treatment room. Data were analyzed bivariately with a Spearman rank correlation test. Result: There was a significant correlation with the incidence of hand eczema with the frequency of handwashing with soap (r=0.305 and p=0.003) and the duration of using latex gloves (r=0.328 and p=0.002) with a weak category correlation (r=0.200-0.399). The frequency of using hand sanitizer, moisturizer, and skin pH did not correlate with the incidence of hand eczema. Conclusion: Frequency of handwashing and the duration of using latex gloves correlated with the incidence of hand eczema, meanwhile frequency of using hand sanitizer, using moisturizer, and skin pH didn’t correlate with the incidence of hand eczema.
The Antimicrobial Activity of Red Palm (Cyrtostachys renda) In Leaf Ethanolic Extract Against Staphylococcus aureus
Authors: Danah Lamanilao  , Christine Grace Encenzo  , Pacot Kent Adriane , Noraima Baraacal  , Elaizah Mapuro  , Apple John Lumingkit  , Jessie Andre Legarta  , Zoe Christina Louise Tungal
Published: August 2022

Medicinal plants are a rich source of secondary metabolites and been utilized since time immemorial as powerful drugs in traditional or alternative healthcare systems. In the light of this marvel, Cyrtostachys renda (Red Palm) is known to possess phytochemicals such as flavonoids, tannins, and steroids. Previous phytochemical studies on Cyrtostachys renda has revealed, the presence of steroids, tannins and flavonoids but none have tested its antimicrobial capabilities. In this study, the researchers used the red palm tree (Cyrtostachys renda) leaves extract as a viable antimicrobial concoction against Staphylococcus aureus. The determination of the Minimum Inhibitory Concentration (MIC) as well as the Zone of Inhibition (ZI) was highlighted in this study for the researchers to assess the overall capability of the Red Palm leaf ethanolic extract as a viable antimicrobial concoction. Apart from the Red Palm ethanolic extract, the researchers had used the ampicillin vial as their positive control and distilled water as their negative control in order to have a point of comparison and synthesis. This study utilized a post test experimental design with three treatments and three repetitions following a complete randomized design format (CRD) to ensure the validity and integrity of the experimental process. Results had shown that Red Palm (Cyrtostachys renda) showed potential viability as an antimicrobial extract as there was a notable presence of Minimum Inhibitory Concentration of (30 mm) using a 30 ml solution and a Zone of Inhibition with a mean of 9.33 mm. The researchers recommend to venture out different species of Palm for comparison of its potential antimicrobial viability.
Pendampingan Penyusunan Company Profile dan Proposal Usulan Insentif Kemenparekraf UMKM Mas Wied Sukoharjo
Authors:   Universitas Veteran Bangun Nusantara, Sari Maria Puspita , Komariah Ainur ,   Universitas Veteran Bangun Nusantara, Prasetyo Rian ,   Universitas Veteran Bangun Nusantara, L Mathilda Sri ,   Universitas Veteran Bangun Nusantara
Published: August 2022

UMKM adalah ujung tanduk dari perekonomian masyarakat. Masa pandemi Covid-19 yang sudah berlangsung lebih dari 1,5 tahun berdampak terhadap pelaku UMKM. Salah satu UMKM yang terdampak Covid-19 adalah Keripik Usus Mas Wied. Sehubungan dengan hal tersebut maka Tim pengabdian masyarakat Progran Studi Teknik Industri melaksanakan kegiatan pengabdian masyarakat di UKM Keripik Usus Mas Wied yang berlokasi di Kecamatan Bulu, Kabupaten Sukoharjo. Tujuan dari kegiatan pengabdian kepada masyarakat ini adalah untuk (1) memberikan pendampingan penyusunan company profile mitra yang merupakan persyaratan wajib dalam pengajuan bantuan insentif Kemenparekraf (2) memberikan pendampingan dalam menyusun proposal bantuan insentif Kemenparekraf. Dalam mencapai tujuan tersebut telah dilakukan beberapa tahapan kegiatan sejak bulan Juni sampai dengan Juli 2021, yaitu dengan diselenggarakannya serangkaian kegiatan pendampingan penyusunan company profile serta penyusunan proposal bantuan Kemenparekraf. Dokumen- dokumen yang diperlukan dalam menyusun company profile dan dalam menyusun proposal semuanya dirinci dan dikumpulkan.
COVID-19 Vaccine Hesitancy Among Parents of Children Under Five Years in the United States
Authors: Fisher Celia B. , Bragard Elise , Jaber Rimah , Gray Aaliyah
Published: August 2022

On 17 June 2022, the U.S. FDA authorized the Pfizer-BioNTech and Moderna COVID-19 (SARS-CoV-2) vaccines for emergency use in children ages 6 months – 4 years. Seroprevalence has increased during the current Omicron variant wave for children under 5 years and the burden of hospitalization for this age group is similar or exceeds other pediatric vaccine preventable diseases. Research following the October 2021 approval of vaccines for children 5 – 11 indicates high prevalence of parental vaccine hesitancy and low uptake, underscoring the urgency of understanding attitudes and beliefs driving parental COVID-19 vaccine rejection and acceptance for younger children. One month prior to FDA approval, in the present study 411 U.S. female guardians of children 1 – 4 years from diverse racial/ethnic, economic, and geographic backgrounds participated in a mixed method online survey assessing determinants of COVID-19 pediatric vaccine hesitancy. Only 31.3% of parents intended to vaccinate their child, 22.6% were unsure, and 46.2% intended not to vaccinate. Logistic regression indicated significant barriers to vaccination uptake including: Concerns about immediate and long-term vaccination side effects for young children, the rushed nature of FDA approval and distrust in government and pharmaceutical companies, lack of community and family support for pediatric vaccination, conflicting media messaging, and lower socioeconomic status. Vaccine-resistant and unsure parents were also more likely to believe children were not susceptible to infection and that the vaccine no longer worked against new variants. Findings underscore the need for improved public health messaging and transparency regarding vaccine development and approval, the importance of community outreach, and increased pediatrician attention to parental concerns to better improve COVID vaccine uptake for young children.
Integration of Nanometer-range Label-to-label Distances and their Distributions into Modelling Approaches
Authors: Jeschke Gunnar
Published: August 2022

Labelling techniques such as electron paramagnetic resonance spectroscopy and single-molecule fluorescence resonance energy transfer, allow access to distances in the range of tens of angstroms, corresponding to the size of proteins and small to medium-sized protein complexes. Such measurements do not require long-range ordering and are therefore applicable to systems with partial disorder. Data from spin-label-based measurements can be processed into distance distributions that provide information about the extent of such disorder. Using such information in modelling presents several challenges, including a small number of restraints, the influence of the label itself on the measured distance and distribution width, and balancing the fitting quality of the long-range restraints with the fitting quality of other restraint subsets. Starting with general considerations about integrative and hybrid structural modelling, this review provides an overview of recent approaches to these problems and identifies where further progress is needed.
Instantaneous Frequency Estimation of FM Signals under Gaussian and Symmetric α-Stable Noise: Deep Learning versus Time-Frequency Analysis
Authors: Razzaq Huda Saleem , Hussain Zahir M.
Published: August 2022

Deep Learning (DL) and Machine Learning (ML) are widely used in many fields, but rarely used in Frequency Estimation (FE) and Slope Estimation (SE) of signals. Frequency and slope estimation for Frequency-Modulated (FM) and single-tone sinusoidal signals are essential in various applications, such as wireless communications, sonar, and radar measurements. In this work, artificial neural network (ANN) and convolutional neural network (CNN) are used in frequency and slope estimation for FM signals under Additive White Gaussian Noise (AWGN) and Additive Symmetric alpha Stable Noise (SαSN). SαS distributions are impulsive noise disturbances found in many communication environments like marine systems; their distribution lacks a closed-form Probability Density Function (PDF), except for specific cases, and infinite second-order statistic, hence Geometric SNR (GSNR) is used in this work to determine the impulsiveness of noise in a mixture of Gaussian and SαS noise processes. ANN is a machine learning classifier, designed with few layers for reducing FE and SE complexity while getting higher accuracy as compared with classical techniques. CNN is a deep learning classifier, designed with many layers for FE and SE, and proved to be more accurate than ANN when dealing with big data and finding optimal features. Simulation results show that SαS noise can be much more harmful for FE and SE of FM signals than Gaussian noise. DL and ML can significantly reduce FE complexity, memory cost, and power consumption, which is important in many systems such as some Internet of Things (IoT) sensor applications. After training DCNN for frequency and slope estimation of LFM signals, the performance of DCNN (in terms of accuracy) can give acceptable results at very low signal-to-noise ratios where TFD fails, giving more than 20dB difference in the GSNR working range.
A Treatment Paradigm Shift: Targeted Radionuclide Therapies for Metastatic Castrate Resistant Prostate Cancer
Authors: Parent Ephraim , Kase Adam M.
Published: August 2022

The recent approval of 177Lu PSMA-617 (Pluvicto®) by the United States Food and Drug Administration (FDA) is the culmination of decades of work in advancing the field of targeted radionuclide therapy for metastatic prostate cancer. 177Lu PSMA-617, along with the bone specific radiotherapeutic agent, 223RaCl2, are now commonly used in routine clinical care as a tertiary line of therapy for men with metastatic castrate resistant prostate cancer and for osseus metastatic disease respectively. While these radiopharmaceuticals are changing how metastatic prostate cancer is classified and treated, there is relatively little guidance to the practitioner and patient as to how best utilize these therapies, especially in conjunction with other more well-established regimens including hormonal, immunologic, and chemotherapeutic agents. This review article will go into detail about the mechanism and effectiveness of these radiopharmaceuticals and less well known classes of targeted radionuclide radiopharmaceuticals including alpha emitting prostate specific membrane antigen (PSMA) -, gastrin-releasing peptide receptor (GRPR) -, and somatostatin targeted radionuclide therapeutics. Additionally, a thorough discussion of the clinical approach of these agents is included and required futures studies.
Palmitic Acid Impedes Extravillous Trophoblast Activity by Increasing MRP1 Expression and Function
Authors: Ashar Yunali , Teng Qiuxu , Wurpel John N. D. , Chen Zhe-Sheng , Reznik Sandra E
Published: August 2022

Normal function of placental extravillous trophoblasts (EVTs), which are responsible for uteroplacental vascular remodeling, is critical for adequate delivery of oxygen and nutrients to the developing fetus and normal fetal programming. Proliferation and invasion of spiral arteries by EVTs depends upon adequate levels of folate. Multidrug resistance-associated protein 1 (MRP1), which is an efflux transporter, is known to remove folate from these cells. We hypothesized that palmitic acid increases MRP1-mediated folate removal from EVTs, thereby interfering with EVTs’ role in early placental vascular remodeling. HTR-8/SVneo and Swan-71 cells, first trimester human EVTs, were grown in the absence or presence of 0.5 mM and 0.7 mM palmitic acid, respectively, for 72 h. Palmitic acid increased ABCC1 gene expression and MRP1 protein expression in both cell lines. The rate of folate efflux from the cells into the media increased with a decrease in migration and invasion functions in the cultured cells. Treatment with N-acetyl cysteine (NAC) prevented the palmitic acid mediated upregulation of MRP1 and restored invasion and migration in the EVTs. Finally, in an ABCC1 knockout subline of Swan-71 cells, there was a significant increase in invasion and migration functions. The novel finding in this study that palmitic acid increases MRP1-mediated folate efflux provides a missing link that helps to explain how maternal consumption of saturated fatty acids compromises the in-utero environment.
Waste Plastic Direct Extrusion Hangprinter
Authors: Petsiuk Aliaksei , Lavu Bharath , Dick Rachel , Pearce Joshua M.
Published: August 2022

As the additive manufacturing industry grows, it is compounding the global plastic waste problem. Distributed recycling and additive manufacturing (DRAM) offers an economic solution to this challenge, but it has been relegated to either small-volume 3D printers (limiting waste recycling throughput) or expensive industrial machines (limiting accessibility and lateral scaling). To overcome these challenges, this paper provides proof-of-concept for a novel open-source hybrid 3D printer that combines a low-cost hanging printer design with a compression screw-based end-effector that allows direct extrusion of recycled plastic waste in large expandable printing volumes. Mechanical testing of the resultant prints from 100% waste plastic, however, showed that combining challenges of non-uniform feedstocks and a heavy printhead for a hangprinter reduced the strength of the parts compared to fused filament fabrication. The preliminary results are technologically promising, however, and provide opportunities to improve on the open source design to help process the volumes of waste plastic needed for DRAM to address the negative environmental impacts of global plastic use.
A Weakly Supervised Tissue-level Approach for Histological Differentiation of Gastric Adenocarcinomas
Authors: Hyeon Dong-Woo , Kim Dongmin , Ryu Wi-Sun , Sung Samuel Hanjoo , Bhattacharjee Subrata , Kim Cho-Hee , Cho Nam-Hun , Moon Damin , Lee Doo-Hee , Kim Hyunki , Shin Hyeong-Chan , Lee Won-Ae , Cho Min-Sun , Choi Heung-Kook , Kang Haeyoun
Published: August 2022

Histologically poor differentiation is associated with lymph node metastasis. Thus, pathological evaluation of biopsy specimens is crucial when treating stomach cancers. Deep learning of WSIs is challenging because the images are enormous. Given the computing limitations, patch-level supervised learning methods have been proposed. However, valuable information is lost when dividing WSIs into smaller patches. Another drawback is the need for pixel-level annotation by a pathologist. It is acceptable to differentiate, i.e., grade, gastric cancer at the holistic tissue level (i.e., under low magnification). We developed a weakly supervised learning technique for tissue-level gastric adenocarcinoma histological differentiation (well-to-moderately or poorly differentiated) and applied global reasoning to tissue-level features. The tissue-level AUROCs of the histological differentiation classifiers were 0.953, 0.969, and 0.943, respectively when data from five hospitals were subjected to threefold cross-validation. Comparison of the Grad-CAM heatmaps of the trained classifier and the pathologists’ annotations confirmed that our weakly supervised model exhibited performed well.
Maritime Policy: Marine Toll to Ensure Availability Of Coconut Trunk Supply Chain On Morotai Island
Authors: Karjono Karjono , Kusumawati Evyana Diah , Rahmadhani Rahmadhani
Published: August 2022

The development of the trunk industry in Indonesia is currently growing from year to year along with the increasing population, technological advances, industry, and science. The furniture industry in the current era is increasing over time because this industrial sector provides unique and creative interior designs and artistic values that offer comfort to support various activities. With the development of the furniture industry, the demand for wood has also increased, which has led to increasingly fierce competition in the wood industry. Morotai Island Regency is located at the northernmost tip of North Maluku Province, bordering the Pacific Ocean. Its area is 4,301 km2. Accessibility there is complex, and development growth is still minimal. This area includes underdeveloped, remote, outermost, and border areas (3TP). To achieve the welfare of the people in Morotai Island, the Marine Toll Road is a solution offered to reduce the price disparity for coconut trunks from Morotai, which must pass through Tobelo Regency and then be sent to Java.
Analysis Of Restriction Rules Of Gross Tonnage Fishing Ship On The Sunda Sea Coast
Authors: Umar Hasdinar
Published: August 2022

The Sunda Strait has a significant enough fishery potential in Indonesia. Fish catches from the Sunda Strait are landed in Pandeglang Regency, one of which is at the Labuan Coastal Fishing Port. The types of fish that are targeted for catching are mackerel and tuna. The high selling price of fish causes fishing operations to continue to be improved. Fishing operations that continue to increase can lead to a scarcity of fishery resources. Therefore, it is necessary to study the rate of fish resource utilization to determine their status. This study aimed to evaluate the rate of exploitation of tuna in the Sunda Strait based on fish catch data on 30 GT vessels and analyze it using policies issued by the Indonesian government. In this study, a simple linear regression method was used. Result of analysis, in 2025, the fish stock is only 21,682 ton, while the number of fish taken is 66,497 ton, which means that in 2025 there will be no more fish because the fish stock has run out and cannot meet the number of fish that needs to be taken.
Analysis Of Wave Height To Ship Motion With Displacement Of 7,597 Tons By Finite Element Method
Authors: Hamzah Hamzah
Published: August 2022

Seakeeping is the ship's ability to stay afloat on the waves. The ship's maneuverability is greatly influenced by external factors related to the state of the sea and the waters in which the ship sails. Calculating seakeeping with various variations of depth, current, and wave height is needed for ship safety when sailing in the calculation of seakeeping using linear strip theory to calculate the response of heaving and pitching movements while roll damping theory for rolling movements. In this study, the ship's motion is calculated using the Finite element method software Hydrodynamic Diffraction and Hydrodynamic Time Response. For variations in wave height and water depth, referring to the conditions of Indonesian waters, from the reference, variations in wave height of 3 m, and 5 m (based on sea state WMO). In contrast, the current variation uses a current with a speed of 10 knots and a current depth of 10 T, 15 T, and 20 T. Based on the data obtained in data processing, it can be seen that the high value of the wave frequency obtained at 90 and 270 degrees wave direction is relatively high. The value of the roll spectrum in the direction of 0 and 270 degrees is large and can cause rolling on the ship. In the direction of 0 and 270 degrees, the wave resistance can be reduced by the ship.
Analysis Of Policy Has Been Established By The Minister On Opening The Export Of Lobster Seed In Indonesia
Authors: Kyaw Aung Ye , Jalil Jalil
Published: August 2022

Seakeeping is the ship's ability to stay afloat on the waves. The ship's maneuverability is greatly influenced by external factors related to the state of the sea and the waters in which the ship sails. Calculating seakeeping with various variations of depth, current, and wave height is needed for ship safety when sailing in the calculation of seakeeping using linear strip theory to calculate the response of heaving and pitching movements while roll damping theory for rolling movements. In this study, the ship's motion is calculated using the Finite element method software Hydrodynamic Diffraction and Hydrodynamic Time Response. For variations in wave height and water depth, referring to the conditions of Indonesian waters, from the reference, variations in wave height of 3 m, and 5 m (based on sea state WMO). In contrast, the current variation uses a current with a speed of 10 knots and a current depth of 10 T, 15 T, and 20 T. Based on the data obtained in data processing, it can be seen that the high value of the wave frequency obtained at 90 and 270 degrees wave direction is relatively high. The value of the roll spectrum in the direction of 0 and 270 degrees is large and can cause rolling on the ship. In the direction of 0 and 270 degrees, the wave resistance can be reduced by th Lobsters are animals that enter into crustaceans that have problematic skin. Adult lobsters can generally be found on a stretch of sand with coral spots with a depth of between 5-100 meters. This condition will cause a low number of young lobsters in the waters. This research was conducted with a case study regarding the policy of opening lobster seed export, which aims to find out how the policy is to open the export of lobster seed. The data obtained is done by reviewing the literature on the internet. Based on the analysis, the export profit of lobster seeds has continued to increase every month since it was again allowed by the government in May 2020. Based on data from the Central Statistics Agency (BPS), lobster seeds began to be re-exported in June 2020 at 32 kilograms, costing the US $ 112,990. The government can help with training and outreach on lobster cultivation. The government can offer Lobster a partnership package to help people start a freshwater crayfish business.
EL RÉGIMEN JURÍDICO DE LAS EMPRESAS DE INTERMEDIACIÓN TURÍSTICA EN CHILE
Authors:   Universidad Católica de Temuco, Martínez Montenegro Isnel ,   Universidad de las Américas
Published: August 2022

The doctrinal and comparative foundation of the legal regime of tourism intermediation companies in Chile can contribute to achieving an improvement in the functioning of tourist economic activity. In the same way, an updated bibliographic support will be achieved with the required scientific level, from the legal perspective and will serve as a consultation tool for the analysis and resolution of problems that are presented to the specialists and legal operators who participate in these processes of marketing of this industry. At the same time, it aims to carry out an approach on the legal regime of tourism intermediation companies and their different modalities, legal, cognitive and regulatory problems that arise according to their different classifications and operation. On the other hand, it must be considered that many of the scientific advances have a direct impact on this economic activity, so that finally, for the commercialization of the national tourism product, a plurality of subjects usually intervene in this heterogeneous market that they are sources of numerous Legal conflicts and their analysis are largely the achievement of this study.
REPRESENTACIONES SOCIALES DEL DESEMPLEO DE HABITANTES DE DIVERSOS CONTEXTOS CULTURALES Y DIFERENTES GRUPOS POBLACIONALES
Authors:   Universidad de Guadalajara, Torres López Teresa Margarita , Parra Osorio Liliana , Munguía Cortés Jazmín Aranzazú , de la Cruz Villarreal Antonio de Jesús , Mosquera Navarro Rodolfo ,   Universidad Libre,   Universidad San Buenaventura
Published: August 2022

Objective: To compare the social representations content of unemployment of inhabitants of diverse cultural contexts and different population groups. Methodology: 690 people (356 women and 334 men) participated, selected by purposeful sampling. The free listing technique was applied to them; the data was analyzed by the thematic content analysis. Results: The categories were found: economic components, personal and social effects, negative emotions and coping with unemployment. All the participants show coincidences in representing unemployment with a global vision, as an unemployed time, without money, that generates poverty, negative emotions, personal and social effects, most included proposals for individual coping and few social coping. Conclusion: Differences were found by age groups and by place of origin. Highlighting the population perspective allows access to their world of meanings and generates bases to establish proposals for individual, institutional and social intervention.