bluuebunny/crossref_metadata_2025 huggingface dataset:
EVALUASI KESESUAIAN LAHAN UNTUK PENGEMBANGAN TANAMAN PORANG (Amorphophallus oncophillus Prain.) DI KECAMATAN WONOSALAM KABUPATEN JOMBANG
Authors: Berbudi Rudini , Siswanto Siswanto , Mindari Wanti
Published: February 2023

Porang merupakan tanaman yang potensial untuk dikembangkan sebagai komoditi ekspor sebagai bahan makanan maupun bahan industri. Umbi porang mempunyai potensi yang sangat besar dalam bidang produksi, namun hal ini belum dikelola secara optimal. Penelitian ini bertujuan untuk mengkaji tingkat kesesuaian lahan di Kecamatan Wonosalam Kabupaten Jombang untuk pengembangan tanaman porang. Penelitian ini menggunakan metode survey yang dilaksanakan dengan teknik pengambilan dan analisa sampel tanah terpilih. Pengambilan sampel dilakukan berdasarkan overlay atau tumpang tindih peta penggunaan lahan, geologi, topografi, dan kelerengan di Kecamatan Wonosalam. Hasil Overlay diperoleh 11 SPL (Satuan Peta Lahan) yang memenuhi karakteristik tiap peta. Hasil penelitian menunjukkan bahwa lahan di wilayah penelitian memiliki kemiringan bervariatif paling rendah 11,3% dan paling tinggi 35%. Tekstur tanah di dominasi oleh tekstur halus dengan nilai tertinggi 62,13% liat pada LD3. Nilai pH masam (4,71 – 5,56). C-organik bervariasi sebesar 0,17 – 3,63%. Nilai KTK di wilayah penelitian yakni 17,99-33,15 Cmol/kg (+). LD1, LD3, KB1, KB2, KB3, KB4, HT1 mempunyai kelas lahan cukup sesuai untuk pengembangan tanaman porang dengan faktor pembatas curah hujan dan kemiringan lereng (S2 wa, e). LD2 mempunyai kelas lahan cukup sesuai dengan faktor pembatas curah hujan (S2 wa). HT2, HT3, HT4 tidak sesuai untuk pengembangan tanaman porang dengan faktor pembatas kemiringan lereng (S3 e). Faktor pembatas didominasi oleh Curah Hujan dan kemiringan lereng pada setiap SPL.
POTENSI PENGEMBANGAN PERKEBUNAN MANGGA BERBASIS ORGANIK DI DESA ORO-ORO OMBOKULON SEBAGAI STRATEGI ADAPTASI PERUBAHAN IKLIM
Authors: Suryandika Fadilla , Maroeto Maroeto , Purnamawati Iis , Windriyati Wiwin , Suryaminarsih Penta , Nugrahani Pangesti
Published: February 2023

Pengembangan perkebunan mangga berbasis organik di Desa Oro-Oro Ombokulon Kabupaten Pasuruan merupakan salah satu upaya yang dapat dilakukan untuk meningkatkan nilai jual mangga. Pengembangan perkebunan mangga organik sejalan dengan upaya mengurangi dampak perubahan iklim. Penelitian ini bertujuan untuk, 1) menganalisis faktor internal dan eksternal pengembangan kebun mangga berbasis organik 2) menyusun alternatif strategi pengembangan kebun mangga organik. Penelitian ini menggunakan pendekatan deskriptif, dengan menggunakan analisis Strengths, Weaknesses, Opportunities, dan Threats (SWOT). Hasil identifikasi faktor internal dan eksternal diperoleh beberapa faktor utama seperti: ketersediaan bahan baku pembuatan pupuk dan pestisida organik, kemauan dan keterampilan petani, keunikan varietas mangga, penurunan produktivitas pada masa transisi, produk organik memiliki nilai jual yang lebih tinggi, pupuk dan pestisida organik sebagai produk sampingan, dan ancaman munculnya pesaing. Berdasarkan analisis SWOT diperoleh kombinasi strategi SO, WO, ST, dan WT yang dapat digunakan untuk pengembangan perkebunan mangga berbasis organik. Beberapa strategi tersebut antara lain pengembangan produk pupuk dan pestisida organik berbasis bahan baku lokal, pengembangan agrowisata mangga organik, pengembangan keterampilan dan penguatan kelembagaan, pengembangan budidaya komoditas musiman yang dapat berdampingan dengan tanaman mangga, promosi dengan menonjolkan keunikan produk, mengajukan paten/hak kekayaan intelektual/lisensi organik atas produk, serta menjalin kerjasama dengan mitra.
Finland in the Mediterranean
Authors:   Tampere University, Melasuo Tuomo
Published: February 2023

This article aimes to shed light on the rich, but rather enigmatic relationship between Finland and the Mediterranean world. These interactions have been approached since Antiquity, but this paper’s focus has been on 19th and 20th centuries and especially on the last three decades. About thirty years ago, when Finland was preparing itself to join the European Union, it also had to build up a real Mediterranean policy of its own. It was in the Corfu European Council in June 1994 when the then-president realised that the country needed such a policy. Thus, in 1995, when Finland joined the EU, it also participated in the Barcelona Euro-Mediterranean Conference and signed the Barcelona Declaration that established the Barcelona Process forming the structures for European Union cooperation with the southern and eastern Mediterranean countries. The participation into this structural process was felt important for Finland mainly for two reasons. Firstly, the country wanted to be a full and active member of the EU and thus contribute to every fi eld of activity that are important for the union. Secondly, we Finns realised that if we wanted the southern European countries to understand and to cooperate with our own ambitions in the northern part of Europe, we needed to show solidarity towards the aims and needs of our southern partners in the Mediterranean. All this resulted in Finland being surprisingly active in all Euro-Mediterranean cooperation environments. This concerned not only offi cial state activities, but also other public sectors as well as civil society actors and NGOs. These EuroMediterranean activities became so many and so multiform that we can deal only with a few of them here as examples.
State Aid Trends in Poland and Finland – Similarities and Differences
Authors:   SGH Warsaw School of Economics, Ambroziak Adam A.
Published: February 2023

State aid is one of the financial instruments available to EU member states for intervention in domestic markets. On the one hand its use is prohibited by Article 107(1) TFEU, but on the other hand there are many exemptions,including regional and horizontal state aid. Given the centralised system for State aid in the EU, one could expect that the volume and structure in terms of forms and purposes of public aid granted should be similar from one member state to the next. Considering the diversity among what are now 27 member states, both from the perspective of experience in managing the economy and the directions of its development, the objective of this article is to capture and evaluate the similarities and differences in the approach taken to State aid as an instrument of intervention in two relatively different countries – Poland and Finland. To this end the comparative analysis will not only cover Poland and Finland themselves but also their respective groups of countries – the Visegrád Group and Scandinavian members of the EU. The above analysis permits the conclusion that the structure of public aid relative to the main purposes of granting differs significantly between Poland and Finland, in favour of Finland, from the perspective of the achievement of the EU objectives associated with the successive economic strategies.
La identidad de género como objeto de prueba. Algunas reflexiones a propósito del caso SUP-JDC-304/2018 y acumulados
Authors: Delgado Nieves Marianela
Published: February 2023

La cuestión relativa a la identidad de género, en especial en aquellos casos en que difiere del sexo que le fue asignado a una persona al nacer, ha supuesto importantes debates en distintos campos. Uno de ellos es precisamente el del proceso judicial. Este texto tiene por objeto analizar el criterio adoptado por la Sala Superior del Tribunal Electoral de Poder Judicial de la Federación de limitar el objetivo de búsqueda de la verdad, en aras de proteger un conjunto de derechos fundamentales, en aquellos casos en que se controvierte la identidad de género de una persona. Sobre el particular, sostendré, por un lado, que no está justificado el sacrificio de tal objetivo, al menos a la luz de las consideraciones del tribunal y, por otro, que, incluso admitiendo que lo está, dicho criterio enfrenta importantes problemas en materia de prueba que hacen dudar sobre la necesidad de buscar una alternativa distinta.
Dynamics of Communal Violence in the Turkish-Kurdish Conflict
Authors: Borsuk Imren
Published: February 2023

Since the 2000s, Turkish-Kurdish communal violence has emerged as a new mode of confrontation in the recent history of Turkey’s Kurdish conflict. Based upon contentious politics literature, this article traces two causal dynamics that have enabled communal violence as a new challenge in the recent history of Turkey’s Kurdish conflict: racialization and countermobilization. While racialization has already been underlined in the literature on the Kurdish conflict, I will argue, however, that a new analytical mechanism that is somewhat neglected in the literature, countermobilization, plays a crucial role in the onset and diffusion of communal violence, especially during high-intensity electoral competitions.
Educación inclusiva “Modelo Cargando la Mochila Juntos”
Authors: Casquete-Tamayo Erolita , Caicedo-Arroyo Mariuxi , Sánchez-López José
Published: February 2023

La inclusión educativa en Ecuador viene presentando serios avances que impactan de lleno en la construcción de una sociedad democrática e igualitaria. En tal sentido, el presente proyecto buscó ampliar los horizontes de inclusión fomentando la interacción entre instituciones educativas comunes y especiales. El objetivo del proyecto fue que estudiantes de ambas modalidades compartan momentos formativos enriquecedores y que también resulte en aprendizaje, todo desde la perspectiva de la inclusión. Los resultados demostraron que los estudiantes se sintieron muy a gusto al compartir momentos gratos, sintiéndose incluidos y contenidos. Conocer como es el mecanismo de las escuelas especiales también fue otro fin que persigue la propuesta. Los resultados reflejaron que ambas modalidades se sintieron contenidas y obtuvieron mucho conocimiento uno respecto del otro y se logró una interacción amena contribuyendo al fortalecimiento de la inclusión educativa.
Activity of users of the web resource "Electronic Library of the National Academy of Sciences of Ukraine" during crisis events
Authors: Shynenko Mykola , Pinchuk Olga
Published: February 2023

The monitoring of the use of the web resource "Electronic Library of the National Academy of Sciences of Ukraine" is aimed at providing informational and methodological support by means of the Google Analytics service in order to track the processes of visiting and using electronic resources, as well as to increase the efficiency of the development, improvement and maintenance of the electronic library site. A comparative analysis of the use of library resources for the period from March 1-May 31, 2022 to September 1-November 30, 2022 during the full-scale Russian invasion of Ukraine was performed. Also, to identify trends in changes in the activity of users of the web resource, a comparative analysis of the use of library resources was performed for the period: 2021. - 2022. The monitoring of the use of the website of the electronic library of the National Academy of Sciences of Ukraine is carried out according to the following indicators: overview of visitors, demographics of visitors, behavior of visitors on the website of the electronic library, technologies for visiting the site, mobile devices used, traffic, information of the statistical module. For scientists, post-graduate students, heads of scientific institutions of the National Academy of Sciences of Ukraine and specialists in the field of librarianship.
SISTEM INFORMASI GEOGRAFIS PEMETAAN KAWASAN RAWAN KEBAKARAN MENGGUNAKAN METODE SEQUENTIAL PATTERN MINING
Authors: Melia Revi , Mutiah Nurul , Rahmayuda Syahru
Published: February 2023

Land and forest fires occur every year in Indonesia, where the cause is human negligence or intentional related to forest deforestation. Land and forest fires, of course, can cause economic, health, social and cultural, ecological and environmental damage. One indicator that is useful as a determinant of the occurrence of land fires is hot spots. To manage hotspot data, data mining can be done, namely by using the sequential pattern mining method to obtain hotspot sequence patterns that will be used as indicators of land fires. In overcoming these problems, a Geographic Information System (GIS) was designed to map the areas prone to land fires in Kubu Raya Regency. The results of this study are maps of the distribution of land fire-prone areas and the pattern of occurrence of hotspots calculated using the sequential pattern mining method which is expected to assist relevant agencies in carrying out mitigation and prevention efforts for land fires, so as to produce the right decisions for handling land fires in the District. Kingdom Fortress. Based on the results of functionality testing using the black box testing method, the SIGPKRK application (Geographical Information System for Mapping Fire Prone Areas) that was built can run and is in accordance with the functions that have been designed. As for the results of testing the system interface using a questionnaire through the Google form which was filled in by 30 respondents, the SIGPKRK application obtained a percentage result of 85.9% which was included in the "Very Good" category.
In vitro and in silico optimization of oral taxane therapy
Authors:   , van Eijk Maarten
Published: February 2023

The taxanes, paclitaxel, docetaxel, and cabazitaxel, are essential in the treatment of various solid tumors. Oral formulations of these compounds are being developed, which can provide a more patient-friendly and cost-effective alternative to the common intravenous route of administration. This thesis describes several projects that were undertaken to optimize the treatment with these oral formulations. In the first chapters, we provide an overview of solid tumor types in which enzymes, that normally play a role in breaking down the taxanes in the liver and intestines, are present. We also show that these enzymes are a mechanism by which breast cancer cells become less sensitive to treatment with docetaxel, and that this may be overcome by adding specific enzyme inhibitors, like ritonavir, to treatment with docetaxel. In the second chapter, we demonstrate how mathematical models, that describe the behavior and the effect of oral taxanes in the body, can be used in their development. With these models, we were able to exclude genetic differences as a source for large variation in oral docetaxel plasma concentrations between patients. Additionally, we show that these models can be used to capture the effect of formulations on plasma concentrations of paclitaxel, and to predict a safe starting dose for first-in-human studies with oral cabazitaxel based on data from mice. The third chapter addresses how the administration route and schedule may affect treatment efficacy and toxicity. We conclude that a weekly docetaxel schedule reduces bone marrow toxicity compared to a three-weekly schedule. Moreover, an oral formulation optimizes exposure to docetaxel which may improve treatment efficacy. Taken together, these research efforts fill relevant knowledge gaps for the development of oral taxanes, which may ultimately lead to optimized treatment of patients with these formulations.
The Basic Study on the Development of Action Learning-Based Korean Similar Grammar Teacher Education Program
Authors:   The Korean Society of Culture and Convergence, Son Joohee
Published: February 2023

The purpose of this paper is to provide basic data necessary to develop a teacher education program to strengthen similar grammar capabilities of Korean language teachers of less than 5 years by applying Action Learning techniques. To achieve this purpose, the core competencies of similar grammar teachers were presented, and the suitability of behavioral learning and behavioral learning procedures were derived to set the direction of development of the program. Based on the development direction, a draft of a teacher education program in the area of similar grammar was prepared, and the final draft was confirmed through expert review. The procedure of Action Learning was constructed in four stages, and similar grammar teacher education programs and examples were presented. In addition, for the completeness of this study, the implementation of the program proposal and the applicability of other areas other than grammar were proposed as follow-up studies.
A Study on the Meaning of Spring in Gobong's Han-si
Authors:   The Korean Society of Culture and Convergence, Kim Jinwook
Published: February 2023

The purpose of this paper is to understand … When I read Gobong's poems, the first thought that comes to my mind is, “Why did Gobong sing so many spring songs?” As such, the temporal background of Gobong's poetry is biased toward spring. Spring was a special time for Kobong. The purpose of this discussion is to consider how spring was special to Gobong. Before the full-scale discussion, I looked at how Gobong thought of poetry. This is because Kobong's perception of poetry is reflected in his works. By examining Gobong's perception of poetry and how it was embodied in actual works, we discussed what spring meant to Gobong. How one perceives spring is inevitably influenced by the inherent properties of spring. Even if you are not a philosopher, everyone recognizes spring as the beginning of the season and the beginning of life. The reason why Gobong desperately wanted this attribute of spring was related to himself who was weak. Gobong always hoped for life in life, and poeticized it. This is one of the great characteristics of Gobong's poetry world.
Effects of Perceived Positive Parenting Attitudes on University Students' Interpersonal Harmony and Psychological Well-being: Mediating Effect of Self-esteem Stability
Authors:   The Korean Society of Culture and Convergence, Park Gyeonghee , Lim Sujin
Published: February 2023

The purpose of this study was to investigate the effect of positive parenting attitudes perceived by university students on interpersonal harmony and psychological well-being, and to examine whether self-esteem stability plays a mediating role. To this end, 250 university students in K province were administered parental parenting attitudes, interpersonal harmony, psychological well-being, and self-esteem stability scales, and the final 239 data were analyzed. For the collected data, SPSS Win 22.0 and AMOS 22.0 were used for correlation analysis, the fit of the measurement model and the structural model was verified, and the mediating effect of the final model was analyzed. As a result of the study, first, the perceived positive parenting attitude showed a significant effect on the interpersonal harmony and psychological well-being of university students. It was found that the more positive the parenting attitude, the higher the interpersonal harmony and psychological well-being. Second, in the relationship between perceived parenting attitude, interpersonal harmony, and psychological well-being, self-esteem stability showed a partial mediating effect. Through the results of this study, it was confirmed that parenting attitude is a variable that predicts interpersonal harmony, psychological well-being, and self-esteem stability of university students. Finally, the results of this study were discussed and suggested.
Analysis of Korean Wordplay Culture
Authors:   The Korean Society of Culture and Convergence, Kim Mihyoung
Published: February 2023

The purpose of this paper is to understand the Korean Wordplay Culture. A certain culture in a society typically exists with a phenomenological characteristic and foundational mentality. In order to analyze the wordplay culture, this paper first discloses phenomena of wordplay, notes systematic characteristics that enable such phenomena, and describes psychology of enjoying such culture. Various types of Korean wordplay include shortening syllable, lengthening syllable, modifying word composition, modifying phoneme, modifying syllable, repeating same sound, inverting syllable, homonym, making parody, using English pronunciation, modifying passage component, antithetical arrangement, talking at cross purposes, and acrostic poem. Main features of distinct relationship between wordplay and Korean language are easy communication post modification through superb readability, unconstrained composition through segmental characteristic, flexible formation of meaning through motivation, and new ideas for modifying shape due to easier separation and combination of strokes. A survey of 100 college students on the question of when they use wordplay showed that respondents use wordplay for convenience, humor, and change of mood. Wordplay as an alternative for verbal violence is another notable response.
Analysis of the Relationship Between Stress, Self-efficacy, and Self-esteem on the Career Maturity of University Students Using GSCA-SEM
Authors:   The Korean Society of Culture and Convergence, Lee Donguk
Published: February 2023

The purpose of this study is to confirm the relationship between stress, self-efficacy, and self-esteem and the mediating effect of self-esteem on career maturity in university students. 1,365 university students in the 14th(2020) of the ｢Youth Panel｣ conducted by the Korea Employment Information Service were selected as research subjects. The data of this study were analyzed through a structural equation model using SPSS 26.0 and GSCA Pro 1.1.8. First, university students' stress had a negative effect on self-esteem, but had no significant effect on career maturity. Second, self-efficacy had a significant positive effect on self- esteem and career maturity. Third, stress had a negative effect on career maturity with self-esteem as a fully mediating effect. Self-efficacy had a positive effect on career maturity with self-esteem as a partial mediating effect. The results of this study can be used as basic data for the development of a career support model to promote and strengthen the career maturity of university students.
MZ Generation's Perception of University Evaluation: Focusing on the Difference Between Generations
Authors:   The Korean Society of Culture and Convergence, Shin Hayoung , Cho Sungbum
Published: February 2023

The purpose of this study is to analyze the awareness about unverisyt of MZ generation (millennials and Z generation) comparing the other generatios, For this study, questions related to awareness, perception, and demand for university evaluation were independently developed, and 1,458 people were randomly sampled across all generations from their 10s to 90s, and a survey was conducted. The MZ generation group of 859 (58.9%) revealed a statistically significant difference in awareness level from other generations regarding the publicity, reliability, and accountability of the university. Through the results of this study, the direction of improvement of the university evaluation system and the plan to raise awareness were suggested.; based on the perception about the university evaluation system and university evaluation elements of MZ generation; as direct stakeholders and beneficiaries as students and graduates.
A Study of English Dialogue Activity Based on Flipped Learning
Authors:   The Korean Society of Culture and Convergence, Yoon Heejeong
Published: February 2023

The purpose of this paper is to look into the effects of flipped learning with English dialogue activity for EFL English speaking proficiency, and self-efficacy. For this study, 40 college students were chosen as the participants and asked to participate in creating dialogue and practicing the dialogue in the form of group activity. It was implemented for 12 weeks. In order to measure the students’ speaking proficiency, pre and post speaking tests were performed before and after dialogue activity based on flipped learning. In addition, questionnaires of self-efficacy were conducted for data collection. The following results have been showed in this study; first, this study showed that there was significant improvement in students’ speaking evaluation. Especially, there was the greatest improvement in fluency. Second, there was positive change in the self-efficacy. Theses imply that dialogue activity based on flipped learning had a positive effect on improving students' speaking achievement, and self-efficacy.
A Study on the Analysis of DISC Behavior Types of National Leaders
Authors:   The Korean Society of Culture and Convergence, Lee Yeonjoo , Song Youngsun
Published: February 2023

This study was conducted to improve the understanding of leaders' leadership in the future by analyzing the behavioral types of the three leaders (Moon Jae In, Kim Jong-un, and Trump), who were the main figures in the period closest to the peace regime on the Korean Peninsula. DISC behavioral type diagnostic tools were used to analyze the characteristics and leadership types of the three leaders. The expert Delphi technique was used as an analysis unit for the language of the three leaders and observable daily behavior. As a result of the analysis, President Moon Jae In was analyzed as an investigator who was careful with the SC type and solved the problem based on principles. Chairman Kim Jong-un was judged to be a delicate but decisive type as an SD type. Trump emphasized behavior and speed as type D, and was analyzed in detail as a result-oriented type. Based on the analysis results, the prediction of similar types of leaders in the future is as follows. First, a leader of a similar type to President Moon Jae In (SC type) forms a complementary partnership with a leader of the same type as Trump (D type). In addition, Moon Jae In and Kim Jong-un share internal motives and community values when the same S-type leader meets. Second, leaders with type D like Kim Jong-un (SD) and Trump (D) have something in common in the speed and way of pursuing goals, but leaders with S like Kim Jong-un tend to value promises and trust very much when pursuing goals. A leader of the same type as Kim Jong-un can take his own steps when he cannot trust his opponent.
Research Trends on Students on Academic Probation through Keyword Network Analysis: Focusing on Domestic Academia Journals Published from 2012-2022
Authors:   The Korean Society of Culture and Convergence, Lee Jeeyoung
Published: February 2023

The purpose of this paper is to examine the trends of academic probation research through keyword network analysis, and to suggest the direction of academic probation research in the future. The key words were selected using Textom program, and the 1-mode network matrix was constructed and visualized. The analysis results are as follows. 1)The papers were published in 96 journals in five research over a 10-year period. 2)Research on academic probation is mainly focused on ‘program development and analysis’, ‘participation in programs of academic warnings’, ‘experience of academic warnings’, and ‘the impact of academic warnings on college life. 3)In the first period, many studies were conducted to identify the characteristics, status, and cause of academic warnings. In the second period, research on the process of overcoming academic warnings and counseling experiences was conducted, and in the third period, the most research was conducted on the development and evaluation of support programs for academic warnings.
Local Culinary Travel Pattern Development Model in Lerep Tourism Village
Authors: Wibowo Setiawan , Muchlis Nur Farah Fajriaty , Yahya Muhammad
Published: February 2023

This article aimed to findout  a model for developing local culinary tourism patterns in the culinary tourism market segment and local food production in Lerep Village, Semarang Regency, especially Ungaran Barat sub-district using the Storynomics Tourism approach. The method used in this research was descriptive qualitative. The data  had been taken from literatur study, observation and  interviews with Lerep Village Government employees.

It's finding showed thatthe development of culinary tourism activities in the Lerep Tourism Village use a model of developing local culinary tourism patterns based on local wisdom which is transformed into local menus created by the Lerep community.

It was concluded that the modeling of local culinary travel patterns provides an insight for tourism actors and prospective tourists to determine travel activities, especially the local culinary world which has strong regional cultural characteristics.

 

 

Keywords : Culinary, Local, Travel, Storynomic, Model
Planning and Mapping of Lunjen Village, Buntu Batu District, Enrekang Regency
Authors: Rahmayanti Firda , Rahman Farid Asfari , J Regina Shintya Dewi , Munajat Mas Dadang Enjat , Novianti Evi
Published: February 2023

This study aims to determine tourist attractions and design a mapping model for the distribution of tourist attractions and amenities in Lunjen Village, Enrekang Regency by making a map of tourist attractions and amenities in Lunjen Village. This research model is applied whose goal is that the results can be implemented. Data was collected through direct observation in the field accompanied by unstructured interviews and documentation.The result of the research is a map of the distribution of tourist attractions and amenities in Lunjen Village using ArcGIS 10.8, which is used as a media aid for tourists in obtaining information about tourist attractions in Lunjen Village, Enrekang Regency. The conclusion in this study is the distribution of tourist attractions by using ArcGIS 10.8 can make it easier to see tourist attractions and amenities in Lunjen Village in the form of a map.
Sistem Geographic Information Web-Based Tourist Attractions Blog in Tomohon City
Authors: Kondoj Telly Hetty Isje , Solang Jeannlly Adri , Rattu Frans Victor
Published: February 2023

Producing a Web-based Information System blog with data visualization containing information on the location of tourist objects that are presented to the public as a promotion of Tomohon tourism based on a Web Blog According to Gween Solomon, lynne Lynne, Web 2.0 Guide for educators (Jakarta: Ptindex index) Blog stands for weblog. a weblog is a type of website developed and managed by individuals using online software or a very user-friendly hosted platform, with room to write. Blogs feature instant online publications and invite the public to read and provide feedback as comments with the existence of a web blog created on blogger.com containing 10 tomohon attractions, it is hoped that it l make it easier for people to determine trips witwithatravele tomohon area which has more than 90 natural, cultural and artificial attractions. The blog content created includes 10 superior tourist attractions that are still operating well and relatively close to the city center of Tomohon and a Google Maps link to allow readers to find location points to be able to reach the most important attractions. This blog can be accessed with electronic devices such as (mobile phones and laptops) that have an internet network.
The Application of the Use of Indonesian Language in Promoting Tourist Destinations to Archipelago Tourists in North Toraja Regency
Authors: Ab Ernawati , Bahri Syamsul , AB St. Aminah , Darmayasa Darmayasa
Published: February 2023

Indonesian language should be encouraged through tourism promotion, especially in the tourism sector, to describe the form of tourism promotion and implementation. Bahasa Indonesia, as a domestic tourism promotion, also describes the role of Bahasa Indonesia as tourism communication to develop and internationalise Bahasa Indonesia in the Department of Tourism and Cultural of North Toraja Regency. This research aims to describe the tourism promotion form in the Department of Tourism and Cultural of North Toraja Regency. Data collection techniques with in-depth interviews through the Snowball Sampling technique for the stakeholder included the private management of tourism attractions, tour guide, and visitors at tourist destination areas. The conclusion of this research is the promotional language to use in the Department of Tourism and Cultural of North Toraja Regency through two options of language: Bahasa Indonesia and English language, but also uses a traditional or local vocabulary which is often used for tourist attraction and describe the local language.
KULUNIGIY 5 SETTLEMENT: THE HISTORY OF ARCHAEOLOGICAL RESEARCH AND NEW DISCOVERIES
Authors:   Surgut State University, Surgut, Russian Federation, VIZGALOV GEORGY , FROLOV IVAN , NIKULIN MIKHAIL ,   «Severnajaarheologija-1», Nefteyugansk, Russian Federation
Published: February 2023

Kulunigiy 5 settlement is a multi-layered monument located in the Middle Ob region, near the village of Ugut in the Surgut district of KhMAO-Yugra. The uniqueness of the monument is due to the large number and high concentration of archaeological structures on a relatively small area. Archaeological structures within the boundaries of the territory of the settlement differ in shape, size and cultural and chronological belonging. The earliest cultural layers of the monument can be attributed to the Mesolithic era, and the latest - the Middle Ages. Objective: systematization of data on the history of the archaeological study of the settlement Kulunigiy 5 and introduction to a wide scientific circulation of the main results of the discoveries of 1996-2021. Research materials: Reporting and project documentation from the branch archive of the scientific and production association «Northern Archeology-1» of Nefteyuganskand the latest scientific publications on the research topic. Results and novelty of the research: The data on the history of the archaeological study of the Kulunigy 5 settlement and their main results for the period 1996-2021 are systematized and introduced into wide scientific circulation, prospects and main directions of archaeological research are outlined on the basis of data obtained during field work.
Evaluation of 3-dimensional rotational venography for the diagnosis of non-thrombotic iliac venous lesion
Authors: Xu Yingjiang , Wu Jian , Cheng Yongjia , Chen Gang , Han Xinqiang , Sheng Yuguo , Wu Xuejun , Wang Wenming
Published: February 2023

Background

The purpose of this study was to determine the technical feasibility and safety of 3D rotational venography (3D-RV) in the diagnosis of non-thrombotic iliac vein lesions compared with traditional 2D-digital subtraction angiography (2-DSA).

Methods

The general epidemiological data (including age, gender), clinical manifestations (including major symptom, affected extremity, CEAP classification, comorbidity, stenosis rate), and intra-operative findings (iliac vein indentation position, collateral circulation, procedure time, X-rays dose, contrast agent dosage) of 61 NIVL patients who were assessed by 3D-RV and traditional 2-DSA between October 2018 to October 2022 were obtained and analyzed.

Results

A total of 61 consecutive patients with symptomatic NIVL from our institution were enrolled in this study. With the aggravation of iliac vein stenosis, the proportion of indicators such as contralateral formation and iliac vein compression indentation reflecting the severity of compression under 3D-RV reconstruction increased significantly. Also, significant differences were observed between the 3D-RV and 2-DSA groups concerning procedure time (10.56 ± 0.09 s vs. 12.59 ± 0.37 s; p < 0.01), X-ray dose (41.25 ± 0.21 mGy vs. 81.59 ± 1.69 mGy; p < 0.01) and contrast agent dosage (21.48 ± 0.24 mL vs. 33.69 ± 0.72 mL; p < 0.01). Contralateral iliac vein imaging (p = 0.002), pelvic collateral vein imaging (p = 0.03), and external iliac vein indentation (p = 0.001) were found to influence the severity of iliac vein compression.

Conclusion

3D-RV can display dynamic stereo image information of NIVL, augmenting the information obtained from traditional 2-DSA. Contralateral iliac vein imaging, pelvic collateral vein imaging, and external iliac vein indentation can be used to evaluate the severity of iliac vein compression to some extent.
Applying game-based learning to a primary school class in computer science terminology learning
Authors: Kaldarova Bolganay , Omarov Bakhytzhan , Zhaidakbayeva Lyazzat , Tursynbayev Abay , Beissenova Gulbakhram , Kurmanbayev Bolat , Anarbayev Almas
Published: February 2023

Introduction

Game-based learning is an innovative technique that utilizes the educational potential of videogames in general, and serious games in particular, to enhance training processes and make it simpler for users to attain motivated learning.

Methods

In this study, we propose game based learning for primary school students in computer science terminology learning. Primary school students often engage in game-based learning. Academic accomplishment motivation consequences have been researched extensively. The purpose of this research was to see how successful Game-Based Learnings are in motivating primary school kids to attain academic success. Fifty primary school students in two focus groups participated in the experiment during 10 weeks to test the involvement of game based learning to pupils.

Results

There are two kind of measurements were applied in identifying benefits of game based learning. First, one is the questionnaire that students answered to questions in three categories as Impression, Usability, and User Interface. Second part of measurement is downloading and uploading of hometasks, and their academic performance. Approximately 90% of the students found the game based learning to be beneficial in their studies and remembering computer science terminologies. The children were satisfied with its functionality and ease of use.

Discussion

The results can be useful for educators, instructional and game designers, and researchers from implementation, design and research perspectives.
Experimental study on condensation and acoustic characteristics of steam underwater injection
Authors: Li Yong , Li Hui , Zhang Yonghao , Li Dongyang , Tan Sichao
Published: February 2023

Introduction: Bubbling deaeration is widely applied in marine steam power system, and direct contact condensation (DCC) of steam injected into water under low sub-cooled water is the thermodynamic foundation of this technology. The deaeration process involves complex thermal and hydraulic behaviors, such as violent turbulence, interfacial mass transfer, and multiphase flow etc., which induce significant pressure fluctuation and radiated noise. In this paper, the two-phase flow regimes and acoustic characteristics of DCC of steam injected into water were studied for sub-cooled temperature ranging from 3℃ to 17℃.

Methods: Using high-speed camera to capture the dynamic plume shape, four typical plumes are found: external chug with encapsulating bubble, oscillating bubble jet, conical and cylindrical jet and cap jet; The underwater acoustic signal is measured synchronously, and the acoustic spectrum is obtained by Fast Fourier transform (FFT).

Results and Discussion: Combined with the plume image, the component sources of the acoustic signal are analyzed. It is found that the first dominant frequency and the second dominant frequency of the acoustic are caused by the evolution of the jet main steam zone and the downstream large steam column respectively; By analyzing the influence of injection parameters on acoustic signal, it is found that steam flow and sub-cooled temperatures have a great influence on acoustic root mean square value and spectrum characteristics. With the decrease of sub-cooled temperature, the main frequency of injection noise signal gradually moves to low frequency. Low frequency noise dominates the radiated noise when the flow field approaches the saturation temperature.
The numerical study on the sensitivity of different auto-conversion parameterization to CCN concentration
Authors: Li Yi , Liu Xiaoli , Yuan Chaoyu
Published: February 2023

The auto-conversion from cloud droplet to raindrop is a process whereby rain drops formed by collision-coalescence of cloud droplets. As an essential link connecting aerosol-cloud interaction, it significantly influences the changes in cloud morphology and precipitation. In order to explore the sensitivity of auto-conversion schemes to cloud condensation nuclei (CCN) concentration, using the auto-conversion scheme in the Thompson scheme (TH-AU) and Milbrandt-Yau scheme (MY-AU), we set four groups of CCN concentrations to simulate a strong convection process in Ningxia region of China. The results show that: The sensitivity of different auto-conversion schemes to changes in CCN concentrations varies significantly, and the aerosol-induced changes in precipitation and convection strongly depend on the auto-conversion scheme. With the increase of CCN concentration, the mixing ratio of cloud droplets increases, and the particle size decreases, resulting in a decrease in the auto-conversion intensity for the two schemes, which makes more supercooled water participate in the ice phase process. Compared with the TH-AU, the MY-AU has lower auto-conversion intensity at the same CCN concentration, the proportion of supercooled cloud droplets participating in the ice phase process is higher than that in the TH-AU, which leads to the raindrop mixing ratio of 4000–6000 m in MY-AU is lower than that in TH-AU at the same CCN concentration, and the mixing ratio of ice phase particles in MY-AU scheme is higher in the convective mature stage, especially snow and graupel particles, and the graupel particle generation height of MY-AU is lower than that of TH-AU. In terms of dynamic structure, with the increase of CCN concentration, more cloud droplets are activated and frozen which makes the enhancement of updraft mainly occur in the upper layer in both schemes, but the stronger gravitational drag caused by graupel particles in MY-AU may enhance the downdraft in the middle and lower layers, which makes the convection of MY-AU decay early at higher CCN concentration. In addition, changes in microphysical processes also lead to differences in cumulative precipitation and accumulated ground graupel-fall of the two schemes. The cumulative precipitation and the accumulated ground graupel-fall of the MY-AU decrease strongly with the increase of CCN concentration because the warm rain process of MY-AU is strongly inhibited. Compared with MY-AU, the warm rain process of TH-AU is not significantly inhibited, which leads to the cumulative precipitation and the accumulated ground graupel-fall of the TH-AU scheme increases when the CCN concentration is 50–200 cm−3 and slightly decreases when the CCN concentration is 200–10000 cm−3.
Comprehensive genomic profiling of upper tract urothelial carcinoma and urothelial carcinoma of the bladder identifies distinct molecular characterizations with potential implications for targeted therapy & immunotherapy
Authors: Tang Qi , Zuo Wei , Wan Chong , Xiong Shengwei , Xu Chunru , Yuan Changwei , Sun Qiangqiang , Zhou Liqun , Li Xuesong
Published: February 2023

Backgrounds

Despite the genomic landscape of urothelial carcinomas (UC) patients, especially those with UC of bladder (UCB), has been comprehensively delineated and associated with pathogenetic mechanisms and treatment preferences, the genomic characterization of upper tract UC (UTUC) has yet to be fully elucidated.

Materials and methods

A total of 131 Chinese UTUC (74 renal pelvis & 57 ureter) and 118 UCB patients were enrolled in the present study, and targeted next-generation sequencing (NGS) of 618 cancer-associated genes were conducted to exhibit the profile of somatic and germline alterations. The COSMIC database, including 30 mutational signatures, were utilized to evaluate the mutational spectrums. Moreover, TCGA-UCB, MSKCC-UCB, and MSKCC-UTUC datasets were retrieved for preforming genomic alterations (GAs) comparison analysis between Western and Chinese UC patients.

Results

In our cohort, 93.98% and 56.63% of UC patients were identified with oncogenic and actionable somatic alterations, respectively. Meanwhile, 11.24% of Chinese UC patients (of 14.50% and 7.63% of UTUC and UCB cases, respectively) were identified to harbor a total of 32 pathogenic/likely-pathogenic germline variants in 22 genes, with DNA damage repair (DDR)-associated BRCA1 (1.20%) and CHEK2 (1.20%) being the most prevalent. Chinese UTUC and UCB patients possessed distinct somatic genomic characteristics, especially with significantly different prevalence in KMT2D/C/A, GNAQ, ERCC2, RB1, and PPM1D. In addition, we also found notable differences in the prevalence of ELF3, TP53, PMS2, and FAT4 between renal pelvis and ureter carcinomas. Moreover, 22.90% and 33.90% of UTUC and UCB patients, respectively, had at least one deleterious/likely deleterious alteration in DDR related genes/pathways. Subsequently, mutational signature analysis revealed that UC patients with mutational signature 22, irrespective of UTUC or UCB, consistently had the markedly higher level of tumor mutational burden (TMB), which was proved to be positively correlated with the objective complete/partial response rate in the IMvigor210 cohort. By comparison, Chinese and Western UTUC patients also differed regrading GAs in oncogenic-related genes/pathways, especially in TP53, RTK/RAS, and PI3K pathways; besides, more alterations in WNT pathway but less TP53, RTK/RAS, HIPPO, and PI3K pathways were identified in Chinese UCB.

Discussions

The in-depth analysis of genomic mutational landscapes revealed distinct pathogenetic mechanisms between Chinese UTUC and UCB, and specific genomic characterizations could identify high risk population of UTUC/UCB and provided information regarding the selection of alternative therapeutic regimens.
Immunotherapy in cervical cancer: From the view of scientometric analysis and clinical trials
Authors: Xing Yang , Yasinjan Feroza , Du Yajie , Geng Huayue , Zhang Ying , He Minghua , Guo Rui , Yang Lei , Cui Jiayue , Mu Dongmei , Liu Ziling , Wang Hong
Published: February 2023

Background

Cervical cancer is the fourth most cancer and the fourth leading cause of cancer-related deaths in women worldwide. Current treatment for patients with advanced cervical cancer is limited. And in the urgent demand for novel effective therapies both as the first and the second line treatment for these patients, immunotherapy is developing fast and has made some achievements.

Methods

This study incorporated 1,255 topic-related articles and reviews from 1999 to 2022 in the Web of Science Core Collection (WoSCC). The WoS platform, Citespace, and VOS viewer provided the annual distribution of publications and citations, the analysis of researching countries and institutions, references, keywords (co-occurrence analysis, burst analysis, and timeline view analysis), and researching authors, respectively. For clinical trials, 720 trials and 114 trials from ClinicalTrials.gov and ICTRP were retrieved, respectively. And 296 trials were finally incorporated into the analysis.

Results

The scientometric analysis showed that the study of immunotherapies in cervical cancer developed fast in recent years. Most publications were from the United States, followed by China. Seven of the top 10 co-cited references belong to clinical trials, and five of them were published in recent five years. There are lots of clinical trials us specific treatment patterns, some of which have represented excellent effects.

Conclusions

Both the scientometric analysis of the 1,255 publications and the analysis of clinical trials showed that the field of immunotherapies in cervical cancer developed so fast in recent years. It was found that a lot of clinical trials using various immunotherapies (mainly vaccine therapy, adoptive cell therapy, immune checkpoint blockade, and antibody-drug conjugate) for advanced cervical cancer are currently ongoing or have represented considerable effect. Centered in immunotherapies, immune checkpoint blockades have represented great efficacy and huge potential, especially combined with other therapies such as chemotherapy, targeted therapy, and other immunotherapies.