bluuebunny/crossref_metadata_2025 huggingface dataset:
Mapping aquifer salinity gradients and effects of oil field produced water disposal using geophysical logs: Elk Hills, Buena Vista and Coles Levee Oil Fields, San Joaquin Valley, California
Authors: Gillespie Janice M. , Stephens Michael J. , Chang Will , Warden John G.
Published: March 2022

The effects of oil and gas production on adjacent groundwater quality are becoming a concern in many areas of the United States. As a result, it has become increasingly important to identify which aquifers require monitoring and protection. In this study, we map the extent of groundwater with less than 10,000 mg/L TDS both laterally and vertically near the Elk Hills, Buena Vista and Coles Levee Oil Fields in the San Joaquin Valley, California and note evidence of effects of produced water disposal on salinity within the Tulare aquifer. Subsurface maps showing the depth at which groundwater salinity is less than 10,000 mg/L (or Base 10K) in the Tulare aquifer are generated using geophysical logs and verified by comparison to water sample analyses. The depth to Base 10K ranges from 240 m (800 ft) in Elk Hills to 800 m (2650 ft) in the adjacent Buena Vista syncline and is 670 m (2,200 ft) deep in the Coles Levee area to the east. Log-calculated salinities show a relatively smooth increase with depth prior to disposal activities whereas salinities calculated from logs collected near and after disposal activities show a more variable salinity profile with depth. The effect of produced water injection is represented by log resistivity profiles that change from low resistivity at the base of the sand to higher resistivity near the top due to density differences between the saline produced water and the brackish groundwater within each sand. Continued post-disposal logging in new wells in the 18G disposal area on the south flank of Elk Hills shows that injected water has migrated approximately 1,200 m (4,000 ft) downdip (south) over a period of 20 years since the inception of disposal activity.
Aportación del Camino de Santiago al desarrollo local: características territoriales y repercusiones económicas en el tramo palentino
Authors: Hortelano Mínguez Luis Alfonso , Fernández Sangrador Lía
Published: March 2022

El Camino de Santiago Francés, a su paso por la provincia de Palencia, constituye un renovado recurso para el desarrollo local de los municipios inmersos en el itinerario tras la crisis financiera del 2008 y la celebración del Año Santo Jacobeo en 2010. A partir de estos antecedentes, el objetivo del artículo pretende analizar y comprobar cómo ha repercutido el Camino en los aspectos socioeconómicos por el territorio que atraviesa en la segunda década del nuevo milenio. La metodología utilizada se ha basado en la obtención de datos de fuentes primarias y secundarias, el trabajo de campo y la representación cartográfica de los indicadores temáticos a lo largo del sendero jacobeo. El Camino, en el tramo palentino, contribuye a la generación de riqueza local por el gasto de los peregrinos y de los turistas pero no de forma suficiente para frenar la pérdida de población y combatir el elevado grado de envejecimiento. De cara al futuro inmediato, tras la parálisis provocada en el Camino por la pandemia de la Covid-19 se abre un periodo de incertidumbre que repercutirá de forma negativa en el tejido de la oferta turística a pesar de la celebración del Año Santo Jacobeo 2021/2022.
The use of multimodal narratives to explore English language learners' identity construction and re-construction
Authors: Dégi Zsuzsanna
Published: March 2022

The present paper aims to provide an insight into English language learners’ beliefs, their ideal foreign language self and their language learner identity formation and transformation presented during the analysis of a set of visual and written narratives. The research involved 56 pupils who were asked to draw two portraits of themselves, one before being able to use English and one after, when they can already use the language. In order to better understand and interpret the drawings, students were also asked to provide a short, written description or explanation of their drawings. Results show that development in English as a foreign language comes with physical, professional, relational, experimental and psychological changes. Moreover, students’ answers suggest that they consider English language knowledge to be valuable and needed for understanding different applications, movies, TV-series, songs, books and other cultures. They believed that lack of English language knowledge excludes them from participating in such activities.
Analisis Fatwa DSN MUI Mengenai Pembiayaan Multijasa dengan Akad Ijarah pada BMT
Authors: Maulana Diky Faqih , Rozak Abdul
Published: March 2022

Kehadiran BMT membantu masyarakat kalangan menengah kebawah yang tidak terjangkau oleh perbankan. Salah satu pelayanan masyarakat yang ditawarkan BMT yakni pembiayaan ijarah multijasa. Lembaga Keuangan Syariah yang mengeluarkan pembiayaan multijasa dengan akad ijarah harus mengikuti ketentuan Fatwa DSN-MUI Nomor 09/DSN-MUI/IV/2000 tentang pembiayaan ijarah. Ditetapkannya fatwa tersebut, pasti berawal dari sebuah latar belakang dan alasan-alasan penting. Selain itu, proses ijtihad yang dilakukan oleh DSN-MUI dalam menetapkan fatwa di atas juga menarik untuk dikaji. Berangkat dari hal tersebut, perlu kiranya dilakukan kajian analisis terhadap fatwa Dewan Syariah Nasional Majelis Ulama Indonesia (DSN-MUI) Nomor 09/DSN-MUI/IV/2000 tentang ijarah dan dampaknya pada Baitul Maal Wattamwil (BMT). Penelitian ini merupakan penelitian kualitatif yang bersifat studi pustaka. Hasil penelitian menunjukkan bahwa fatwa DSN-MUI No.09/DSN-MUI/IV/2000 mengharuskan BMT menyediakan barang yang disewakan atau jasa yang dimiliki dan dilakukan oleh pihak BMT, bukan jasa yang dimiliki oleh pihak lain. Terkait objek akad, belum ada penegasan dalam Fatwa DSN No. 44/DSN-MUI/VII/2004 tentang Pembiayaan Multijasa maupun fatwa tentang ijarah. Karena menurut Al-Kasani, dalam persewaan tidak dapat diterapkan pada uang,  begitu pula ketentuan ijarah tidak mengatur secara jelas objeknya. Hal ini melahirkan perbedaan persepsi bagi BMT terkait objek ijarah dan rentan adanya pembiayaan dalam bentuk modal. Ketentuan ujrah dalam Fatwa disebutkan bahwa besarnya harus disepakati di awal dan dinyatakan dalam bentuk nominal bukan dalam bentuk prosentase, namun dalam praktiknya banyak BMT yang menerapkan ujrah dalam satuan prosentase. Kata Kunci: Fatwa DSN-MUI, Pembiayaan Ijarah Multijasa, BMT.
Obligasi Syariah di Indonesia Tinjauan Terhadap Jenis dan Penerapan Akad Serta Perlindungan Hukum Bagi Investor
Authors: Mena Amertha Nevada Della , Anwar Ahmad Syaifudin
Published: March 2022

Pasar modal adalah tempat yang mempertemukan pihak investor dan pihak perusahaan. obligasi Syariah menjadi salah satu instrument yang tersedia dalam pasar modal. Obligasi Syariah sebagai alternatif bagi investor untuk menginvestasikan dana selain dalam instrument saham dan juga reksa dana, namun patut untuk diperhatikan bahwa bagaimana pengaturan hukum terkait legitimasi obligasi Syariah tersebut, serta jenis akad yang dipergunakan dan bagaimana penerapannya serta yang paling esensial adalah bagaimana perlindungan hukum bagi investor yang telah memilih obligasi Syariah sebagai alternatif dalam berinvestasi. penelitian ini termasuk dalam penelitian normative, yang merujuk kepada peraturan perundangan dan juga literatur terkait. Dan hasil dari penelitian ini adalah Pengaturan mengenai prinsip-prinsip syariah pada obligasi syariah sudah diatur secara lengkap pada peraturan perundang-undangan di Indonesia, meliputi Undang-Undang No.8 Tahun 1995 Tentang Pasar Modal Syariah, Peraturan-peraturan yang dikeluarkan oleh Lembaga terkait serta fatwa DSN-MUI, akad yang dipergunakan dalam obligasi Syariah adalah akad mudharabah dan juga akad ijarah akan tetapi penggunaan  akad  ijārah  muntahiya  bi  al-tamlīk  dalam  Sukuk Ijarah menjadi persoalan karena aplikasi akad tersebut membuka peluang terjadi riba dalam bentuk yang sama dengan bai‟ al-„īnah. Perlindungan terhadap investor diatur dalam pasal 1 butir 7 dan 45 Undang-Undang 8 Tahun 1995 mengenai asas keterbukaan serta adanya jaminan dari MUI dan DSN sebagai legitimasi kebenaran secara syariat atas instrument investasi tersebut.Kata kunci ; Investor, Akad, obligasi Syariah
Penyelesaian Sengketa Dalam Akad Mudharabah Oleh Pihak Pengusaha (Mudharib)
Authors: Arisandy Samsul , Rosyda Farrah Syamala
Published: March 2022

AbstractThe problems with mudharabah financing can occur either in default or against the law. Dispute resolution can be pursued as a step to resolve the problem. this can be pursued by the Mudarib.The purpose of this research is to know for completion within mudharobah covenants and the steps taken by the mudharib whose mudharabah contract was problematic.The research method used is a normative method using data in the form of literature in the form of legislation, DSN-MUI fatwas, books and literature that support this research. The collected data was analyzed using analytical description method in order to answer the problem.There are 3 (three) dispute resolutions in the mudharabah contract through restructuring, non-litigation dispute resolution such as negotiation, mediation and arbitration and litigation dispute resolution through religious courts. For mudharib, the first step in dispute resolution is to apply for restructuring. Restructuring can be an easy means of solving financing problems.Keyword: Dispute Resolution, Mudharabah, Mudharib  AbstrakPermasalahan pada pembiayaan mudharabah bisa saja terjadi baik wanprestasi ataupun perbuatan melawan hukum. Penyelesaian sengketa dapat diupayakan sebagai langkah menyelesaikan permasalahan tersebut. hal ini dapat diupayakan oleh pihak Mudharib. Tujuan dari penelitian ini adalah untuk mengetahui penyelesaian dalam akad mudharobah dan langkah dilakukan oleh mudharib yang akad mudharabahnya bermasalah.Metode penelitian yang digunakan adalah metode normatif dengan menggunakan data-data berupa pustaka berupa peraturan perundang-undangan, fatwa DSN-MUI, buku-buku dan literatur yang mendukung dalam penelitian ini. Data yang terkumpul dianalisis menggunakan metode deskripsi analitis agar dapat menjawab permasalahan.Penyelesaian sengketa dalam akad mudharabah ada 3 (tiga) dapat melalui Restrukturisasi ulang, Penyelesaian sengketa non litigasi seperti negoisasi, mediasi dan arbitrasi serta Penyelesaian sengketa litigasi melalui pengadilan agama. Bagi mudharib, langkah awal dalam penyelesaian sengketa dapat mengajukian restrukturisasi ulang. Restrukturisasi ulang dapat menjadi sarana mudah dalam penyelesaian permasalahan pembiayaan.Kata kunci: Penyelesaian sengketa, mudharabah, mudharib
Entrevista com Simon J. Littlewood
Authors: Artese Fla , Cunningham Susan , Darendeliler Ali , Vaid Nikhilesh R. , Littlewood Simon J.
Published: March 2022

Conheci Simon Littlewood em Londres, durante o 8º IOC, em 2015. A Sociedade Britânica de Ortodontia estava sediando o Congresso Internacional da WFO, e Simon
palestrou sobre contenção, na programação científica do evento. A essa altura, eu tinha experiência suficiente na especialidade para reconhecer a importância e o valor do assunto. E, que surpresa encantadora, um orador talentoso discorrendo sobre esse tema bastante árido! A sua capacidade de envolver o público era admirável e eu deixei a sala de conferências com algumas informações que me marcaram, tanto sobre contenções quanto sobre palestras. Tive a oportunidade de ouvi-lo em outros congressos internacionais e de conhecê-lo melhor por meio da WFO e de amigos em comum. Simon é uma dessas pessoas de quem não é difícil tornar-se amigo. Sempre uma conversa agradável, com uma perspectiva entusiasmada da vida e da profissão, tudo misturado com um grande sorriso e um sotaque britânico encantador.
C expander: aplicação clínica baseada nas respostas dentoesqueléticas obtidas por avaliação tomográfica
Authors: Eto Luiz Fernando , Bicalho José Eymard , Oliveira Guilherme Augusto Melo de , Kim Seong-Hun
Published: March 2022

OBJETIVOS: O objetivo do presente trabalho é apresentar as etapas de confecção do aparelho C expander, um disjuntor original da Coreia do Sul (filosofia biocriativa) com
seis mini-implantes no palato, corpo de acrílico e parafuso expansor convencional, sem apoio em dentes, ilustrando com um caso clínico os efeitos dentários e esqueléticos
ocorridos em uma paciente adulta que apresentava mordida cruzada posterior unilateral e recessões gengivais nos dentes posteriores. MÉTODOS: Para avaliar as alterações dentárias ocorridas após o uso desse aparelho, foram utilizadas tomografias computadorizadas de feixe cônico antes e após o procedimento. RESULTADOS: Os resultados tomográficos mostraram um aumento no comprimento maxilar após a disjunção e uma ausência de inclinação dos molares superiores. CONCLUSÃO: o aparelho C expander é efetivo nas disjunções palatinas de pacientes adultos e não mostra efeitos colaterais nos dentes superiores posteriores, por não os utilizar como apoio para ancoragem do aparelho.
Decentralisation of Educational Management: Evidence from Ghanaian Basic Schools
Authors: Kyeremeh Alex , Kor Jacob Aaworb-nang Maabobr
Published: March 2022

Although touted as having impacts on educational outcomes in some countries not much attention has been given to evaluating the operations of the District Oversight Committees toward implementing decentralised education management functions at the basic level of education, on a national level. The study sought to evaluate the role of DOECs toward decentralization of school management at the basic level of Education and also identify existing challenges towards their operations. A mixed design was employed in this study. A multistage random sampling technique was used to select 408 public and private schools from 9 regions and interviews conducted with selected District directors and Headteachers from which schools are selected. It was found that the District Education Oversight Committees were sometimes involved in their roles toward Personnel management, Organization of Instruction, and in Planning and Structures. While it was found that DOECs were particularly active in supervision and monitoring in schools they were less active in some personnel management functions as the power and means to perform such functions remained centralised. Key challenges which affected the operations on the DEOCs were financial constraints, inadequate logistics for the operations, inadequacy and delay in supply of teaching and learning materials, delays in decisions on appointments, promotions and sanctions, political interferences, poor communication, and difficulty in monitoring and supervision of school. It was recommended that there a more improved form of devolution may be needed to address some lingering challenges observed after decade of practicing educational decentralization. Again, there should be a consistent supervision of school instructions at various levels of decentralization of educational management to ensure standard is maintained.
When concept-based language instruction meets cognitive linguistics: teaching English phrasal verbs with up and out
Authors: Qin Jie , Wu Zhangxin , Zhong Shuneng
Published: March 2022

The study investigates the efficacy of instructional practices informed by an integration of cognitive linguistics (CL) and concept-based language instruction (C-BLI) on EFL learners’ learning of polysemous English phrasal verbs. Such efficacy is also compared with that of a traditional instruction in which meanings of phrasal verbs are considered as unanalyzable and arbitrary and acquired through rote-learning. In an 8-week quasi-experiment with a pretest, immediate-posttest, delayed-posttest design, 93 intermediate-level Chinese university students were divided into a cognitive, a traditional, and a control group. The results suggested that the CL-C-BLI integrated instruction facilitated the learners’ memorization and recall of the phrasal verbs’ meanings, but it was not so effective in promoting their recognition and distinction of phrasal verbs’ meanings in sentential contexts as the traditional instruction did. This study contributes to the field by adding evidence of innovative instructional practices in ways that are both usage-inspired and grounded in developmental education.
Acacia arabica (Lam.) Willd. On osteoblastogenesis, osteoblast proliferation, osteoclastic activity, and bone calcium mineralization
Authors: Kakadia Nimisha , Vegad Kunjal , Kanaki Niranjan
Published: March 2022

Objectives

Since ancient times Acacia arabica (Lam.) Willd. (AA) consumed for the bone and muscle related disorder like the bone fracture, rheumatoid arthritis, and bone loss. To study the effects of the aqueous (AAA) and ethanolic extract (AAE) of AA on osteoblast proliferation and differentiation, osteoclastic activity and bone matrix mineralization using in vitro primary bone-marrow cultures.

Methods

Effect of AAA and AAE was estimated using four in vitro assays. Primary bone marrow cell culture, isolated from rat femur bone, was used for all the assays. Cell growth and viability were assessed by standard colorimetric assays like MTT assay. The differentiation of mesenchymal stem cells into osteoblastic lineage was evaluated by the measuring the levels of the osteoblast-specific marker, alkaline phosphatase. Antiosteoclastic action and matrix mineralization were measured using TRAP assay and Alizarin red-s staining assay, respectively.

Results

It indicates that AAA causes more increase in osteoblast differentiation and a reduction in osteoclast activity as compared to AAE. In osteoblast proliferation assay, AAA was found to promote more cell proliferation as compared to AAE. Higher concentrations of AAA significantly increased mineralization of bone-like matrix.

Conclusions

The extracts of AA have a significant positive influence on osteogenesis and they inhibit osteoclastogenesis. Hence, these extracts have the potential to be developed as a therapy for osteoporosis.
Evaluation of umbilical cord immune cells in pregnancies with autoimmune disorders and/or methylenetetrahydrofolate reductase polymorphisms
Authors: Sekkin Eser Miray , Ulutas Ugur Yesim , Tanacan Atakan , Gurbuz Hekimoglu Rumeysa , Cakar Ayse Nur , Beksac Mehmet Sinan
Published: March 2022

Objectives

To evaluate umbilical cord immune cells in pregnancies with autoimmune disorders (AID) and/or methylenetetrahydrofolate reductase (MTHFR) polymorphisms.

Methods

Umbilical cords were obtained from seven AID women without MTHFR polymorphisms, eight with AID and MTHFR polymorphisms, nine with MTHFR polymorphisms, and eight with neither. Umbilical cords were assessed immunohistologcally by anti-CD4, anti-CD8, anti-CD14, anti-CD19, anti-CD21, and anti-CD56 antibodies in six umbilical cord zones: 1) arterial wall 2) periarterial zone 3) venous wall 4) perivenous zone 5) intervascular zone, and 6) subamniotic zone.

Results

AIDs and MTHFR polymorphisms had an effect on the number and composition of CD4+ cells in the venous wall. The presence of a MTHFR polymorphism may affect the number and morphology of CD4+ cells in the subamniotic zone. CD8+ cell distribution is substantially influenced by the presence of maternal risk factors. The co-existence of AID with MTHFR polymorphism has a prominent effect on the number and morphology of CD14+ cells, especially in the arterial wall. CD19+ cells were only observed in the control group in the venous wall, perivenous zone, and intervascular zone. CD21+ cells were only observed in the arterial wall of the control group and the intervascular zone of the AID group with different morphologic features. The number and morphology of CD56+ cells is prominently affected by the presence of maternal risk factors.

Conclusions

Umbilical cord stem cell and immune cell composition may be affected by the presence of risk factors like MTHFR polymorphisms and/or AID.
Tort Common Law Future: Preventing Harm and Providing Redress to the Uncounted Injured
Authors: Bublick Ellen M.
Published: March 2022

How do courts root themselves in traditional tort principles and policies and also develop tort common law in ways that befit contemporary values? This essay argues that judges should weave classic tort aims of harm prevention and redress with contemporary norms of equality of persons, to provide a fuller accounting to people foreseeably risked and harmed by projects undertaken for financial gain. In essence, common law courts must re-ask the crucial question of who is a neighbor in a shrinking world in which risks and consequences can be traced somewhat farther. The article commends a few recent decisions that compel legal regard for a broader cohort of injured people and promote care for their wellbeing. It also encourages scholars to engage more deeply with the state court decisions that determine tort law’s reach.
Combining one and two photon polymerization for accelerated high performance (3 + 1)D photonic integration
Authors: Grabulosa Adrià , Moughames Johnny , Porte Xavier , Brunner Daniel
Published: March 2022

Dense and efficient circuits with component sizes approaching the physical limit is the hallmark of high performance integration. Ultimately, these features and their pursuit enabled the multi-decade lasting exponential increase of components on integrated electronic chips according to Moore’s law, which culminated with the high performance electronics we know today. However, current fabrication technology is mostly constrained to 2D lithography, and thermal energy dissipation induced by switching electronic signal lines presents a fundamental challenge for truly 3D electronic integration. Photonics reduces this problem, and 3D photonic integration is therefore a highly sought after technology that strongly gains in relevance due to the need for scalable application-specific integrated circuits for neural networks. Direct laser writing of a photoresin is a promising high-resolution and complementary metal-oxide-semiconductor (CMOS) compatible tool for 3D photonic integration. Here, we combine one and two-photon polymerization (TPP) for waveguide integration for the first time, dramatically accelerating the fabrication process and increasing optical confinement. 3D additive printing is based on femtosecond TPP, while blanket irradiation with a UV lamp induces one-photon polymerization (OPP) throughout the entire 3D chip. We locally and dynamically adjust writing conditions to implement (3 + 1)D flash-TPP: waveguide cores are printed with a small distance between neighboring writing voxels to ensure smooth interfaces, mechanical support structures are printed at maximal distance between the voxels to speed up the process. Finally, the entire chip’s passive volume not part of waveguide cores or mechanical support is polymerized in a single instance by UV blanket irradiation. This decouples fabrication time from the passive volume’s size. We succeed in printing vertical single-mode waveguides of 6 mm length that reach numerical apertures up to NA = 0.16. Noteworthy, we achieve exceptionally low −0.26 dB injection losses and very low propagation losses of −1.36 dB/mm at λ
0 = 660 nm, which is within one order of magnitude of standard integrated silicon photonics. Finally, the optical performance of our waveguides does not deteriorate for at least ∼3000 h after printing, and remains stable during ∼600 h of continuous operation with 0.25 mW injected light.
Biomarkers to target and silence stemness of breast cancer stem cell model: silencing MDR1 by siRNA
Authors: Yıldırım Gamze , Kars Meltem D. , Kars Gökhan , Kılıç Hamdi Ş.
Published: March 2022

Objectives

Aim of the study was to reveal new biomarker genes to target breast cancer stem-like cells (BCSC-like) and then sensitize BCSC-like cells to chemotherapy by silencing MDR1 gene found to be the most suitable target.

Methods

Drug resistance associated genes were screened by cDNA microarray to unveil biomarker genes in drug resistance breast cancer model cells. Drug resistance was then reversed by silencing MDR1 gene in BCSC-like cells. The effect of silencing was monitored by real-time cell proliferation analysis. Differential expressions of MDR1, ALDH1A3, EGFR and BAG4 genes were identified by real-time PCR. P-glycoprotein (P-gp) expression level and its activity were investigated by Western blot and flow cytometry measurements, respectively.

Results

16 new biomarker genes were identified upon gene expression analysis by cDNA microarray. MDR1 gene was selected as the most potent target gene and silencing of it caused down-regulation of MDR1, ALDH1A3, EGFR, BAG4 expression and P-glycoprotein activity and expression in BCSC-like cells. At the end, silenced BCSC-like cells were found to be more responsive to paclitaxel therapy.

Conclusions

In conclusion, siMDR1 silencing is an effective way to reverse multidrug resistance and malignancy. New biomarker genes revealed in this study require to be investigated to target stemness of BC.
'Tue Gutes und rede darüber?' Die Internetauftritte österreichischer Genossenschaftsbanken
Authors: Dietl Katharina , Pernsteiner Helmut
Published: March 2022

Raiffeisenbanken in Österreich leisten durch ihre duale Zielsetzung einen wertvollen Beitrag für ihre Gemeinden. So verfolgen die Banken nicht nur das Ziel der finanziellen Performance, sondern betreiben auch Mitglieder- und Regionalförderung. Da dieser Förderauftrag von jeder Genossenschaft individuell interpretiert wird, ist eine transparente Berichterstattung notwendig, sodass die Stakeholder die Bemühungen der Banken nachvollziehen können. Entsprechend wurde im Rahmen dieses Papers ermittelt, inwieweit österreichische Raiffeisenbanken Auskünfte über ihr Handeln auf den eigenen Websites für die Öffentlichkeit bekannt geben. Die Homepages aller 349 Institute wurden im Hinblick auf deren Auskünfte zu Geschichte, aktuelle Veröffentlichungen, Presse bzw. Newsletter, Vorteile für Mitglieder, Unternehmensphilosophie, Informationen über Sponsoring und Nachhaltigkeit sowie konkrete Einzelprojekte untersucht. Die indexierten Ergebnisse wurden in Bezug zu Unternehmensgröße und Qualifikation der Geschäftsleitung gesetzt; so konnte eine positive Korrelation zwischen der Bilanzsumme beziehungsweise der Qualifikation der Geschäftsleitung und der Auskunftsbereitschaft der jeweiligen Institute erkannt werden.
THE COMPETENCY-BASED TRAINING & ASSESSMENT, AND IMPROVEMENT OF TECHNICAL COMPETENCIES AND CHANGES IN PEDAGOGICAL BEHAVIOR
Authors: Khan Saba , Ahmed Rizwan Raheem , Streimikiene Dalia , Streimikis Justas , Jatoi Munsif Ali
Published: March 2022

This research aims to analyze the improvement of technical competencies and changes in pedagogical behavior on competency-based training and assessment. We developed a modified conceptual model with the help of previous literature. We examined the impact of competency-based training & assessment on traditional teaching methodologies, practical teaching strategies, technical knowledge, and pedagogical & technical components as outcome variables. We also incorporated behavior & psychological aspects of teachers as mediators in our modified conceptual model and examined the mediation between exogenous and endogenous variables. We have collected the data of 458 respondents using a modified structured questionnaire from public and private teachers of Sindh technical and vocational institutions online from different regions of Sindh, Pakistan. For the data analyses, we employed SEM-based multivariate techniques. The findings exhibit that the direct relationship between competency-based training & assessment (independent variable) has a significant and positive influence on traditional teaching methodologies, practical teaching strategies, technical knowledge, and pedagogical & technical components as outcome variables. Similarly, the findings further concluded that behavior & psychological aspects are potent mediators between competency-based training & assessment and traditional teaching methodologies, teaching-learning abilities, practical teaching strategies, technical knowledge, and pedagogical & technical components as outcome variables. Hence, the behavior & psychological aspects of teachers is a vital factor that accelerates the impact of competency-based training & assessment on the dependent variables. The outcomes of this research are imperative theoretical and practical implications, which may guide the direction of future researchers and policymakers of vocational training and education.
Effects of dabrafenib and erlotinib combination treatment on anaplastic thyroid carcinoma
Authors: Choi Yeon-Sook , Kwon Hyemi , You Mi-Hyeon , Kim Tae Yong , Kim Won Bae , Shong Young Kee , Jeon Min Ji , Kim Won Gu
Published: March 2022

Dabrafenib is a BRAF kinase inhibitor approved for treatment of BRAF-mutated anaplastic thyroid carcinoma (ATC) in combination with trametinib. Erlotinib is a tyrosine kinase inhibitor of EGF receptor (EGFR). We evaluated effects of dabrafenib and erlotinib combination treatment on ATC cells in vitro and in vivo. Cell proliferation, colony formation, apoptosis, and migration of ATC cells harboring a BRAF mutation (BHT101, 8505C, and SW1736) were evaluated after treatment with dabrafenib in combination with erlotinib or trametinib. The changes in activation of mitogen extracellular kinase (MEK) and extracellular signal-related kinase (ERK) signaling were also evaluated by Western blot analysis. Effects of these combinations were also evaluated using an in vivo xenograft model. First, we detected EGFR activation in dabrafenib-resistant SW1736 cells using a phospho-receptor tyrosine kinase array. A dabrafenib and erlotinib combination synergistically inhibited cell proliferation, colony formation, and migration, with an induction of apoptotic cell death in all three ATC cells, compared with dabrafenib or erlotinib alone. This synergistic effect was comparable with a dabrafenib and trametinib combination. The dabrafenib and erlotinib combination effectively inhibited phosphorylated (p)-MEK, p-ERK, and p-EGFR expressions compared with dabrafenib or erlotinib alone, while the dabrafenib and trametinib combination only inhibited p-MEK and p-ERK expressions. The dabrafenib with erlotinib or trametinib combinations also significantly suppressed tumor growth and induced apoptosis in a BHT101 xenograft model. The dabrafenib and erlotinib combination could be a potential novel treatment regimen to overcome drug resistance to dabrafenib alone in patients with BRAF-mutated ATC.
Do cypermethrin and fenvalerate disturb the function of the bovine cervix in vitro?
Authors: Wrobel Michal Hubert , Mlynarczuk Jaroslaw , Kowalik Magdalena Karolina
Published: March 2022

This study aimed to investigate the effect of pyrethroid insecticides on the regulation of bovine cervical function. Cervical cells or strips obtained from cows during the periovulation period were treated with cypermethrin and fenvalerate (0.1–10 ng/mL). None of the pyrethroids exerted a cytotoxic effect, whereas only fenvalerate increased the cervical contraction force and mRNA expression of receptor of oxytocin and prostaglandin (PG) synthases. Both pyrethroids inhibited PG secretion and decreased the amount of diacylglycerol, which is the second messenger involved in oxytocin signal transmission, and fenvalerate decreased the myosin light-chain kinase level. These findings indicate that fenvalerate induces greater disruption of cervical function than cypermethrin.
Conocimientos sobre clasificación de residuos hospitalarios en profesionales de enfermería que trabajan en diferentes IPSs de Cartagena
Authors: Orgulloso Bautista Claudia Alejandra , Salas Taborda Hillary
Published: March 2022

Objetivo: Determinar el conocimiento sobre la clasificación de residuos hospitalarios en profesionales de enfermería que trabajan en diferentes IPS de Cartagena, 2021. Materiales y Métodos: Se diseñó un estudio cuantitativo, descriptivo y de corte transversal con una población de profesionales de enfermería que se encontraban laborando en IPS en la ciudad de Cartagena, la muestra fue de 124 individuos a través de un muestreo de bola de nieve, a los que se les aplicó una encuesta estructurada virtual (dividida en dos partes); se realizó un análisis estadístico univariado y bivariado. Resultados: La población estuvo conformada en su mayoría por mujeres en un 90,3% (112), mayores de 36 años un 33,9% (42) y de los estratos 1 y 2 un 59,7% (74). En cuanto a los aspectos laborales el 38,7% (48) son de hospitalización, un 66,9% (83) de instituciones privadas y tienen entre seis a diez años de experiencia un 33,9% (42). Además, de acuerdo con la evaluación de los conocimientos sobre la clasificación de los residuos, se observó que un 58,9% (73) de los profesionales de enfermería tienen un conocimiento regular y presentaron asociación estadísticamente significativa únicamente con la variable sexo (p=0,004) y tipo de institución (p=0,049). Conclusiones: Los profesionales de enfermería presentaron en su mayoría conocimientos regulares en la clasificación de los residuos hospitalarios, en especial los de sexo femenino, con edades entre 31 a 36 años, de estratos 3 y 4, residencia urbana, área de laboratorio, institución privada y tener más de 10 años de experiencia.
Discusión epistemológica sobre los modelos económicos de equilibrio general y agentes heterogéneos
Authors: Barrientos Apumayta Enrique Agapito
Published: March 2022

Este artículo presenta un estudio epistemológico de los fenómenos económicos basados en los modelos EGDE (Equilibrio General Dinámico y Estocástico) y la NEC (Nueva Economía Clásica). También, destaca el impacto y la crítica a los presupuestos teóricos de la predicción en los modelos EGDE, además de sus alcances y limites en materia de política económica realizada por los bancos centrales. Discutimos problemas epistemológicos de los modelos EGDE. Mostramos críticamente los modelos RANK (Modelos de Agentes Representativos Neokeynesianos), HANK (Modelos de Agentes Heterogéneos Neokeynesianos) y TANK (Modelos con Dos Agentes Neokeynesianos), como posibles alternativas para la aplicación en temas macroeconómicos. Nuestro principal análisis está basado en los modelos HANK, como posible herramienta cuantitativa de los MBA (Modelos Basados en Agentes). Así, pretendemos enfatizar la tarea de nuestra crítica para abrir el campo de análisis a los sistemas complejos en ciencias sociales y otros debates epistémicos.
Classification of suspensions over cartesian products of orientation-reversing diffeomorphisms of a circle
Authors: Zinina Svetlana Kh. , Pochinka Pavel I.
Published: March 2022

This paper introduces class G containing Cartesian products of orientation-changing rough transformations of the circle and studies their dynamics. As it is known from the paper of A. G. Maier non-wandering set of orientation-changing diffeomorphism of the circle consists of 2q periodic points, where q is some natural number. So Cartesian products of two such diffeomorphisms has 4q1q2 periodic points where q1 corresponds to the first transformation and q2 corresponds to the second one. The authors describe all possible types of the set of periodic points, which contains 2q1q2 saddle points, q1q2 sinks, and q1q2 sources; 4 points from mentioned 4q1q2 periodic ones are fixed, and the remaining 4q1q2−4 points have period 2. In the theory of smooth dynamical systems, a very useful result is that, given a diffeomorphism f of a manifold, one can construct a flow on a manifold with dimension one greater; this flow is called the suspension over f. The authors introduce the concept of suspension over diffeomorphisms of class G, describe all possible types of suspension orbits and the number of these orbits. Besides that, the authors prove a theorem on the topology of the manifold on which the suspension is given. Namely, the carrier manifold of the flows under consideration is homeomorphic to the closed 3-manifold T2×[0,1]/φ, where φ:T2→T2. The main result of the paper says that suspensions over diffeomorphisms of the class G are topologically equivalent if and only if corresponding diffeomorphisms are topologically conjugate. The idea of the proof is to show that the topological equivalence of the suspensions ϕt and ϕ′t implies the topological conjugacy of ϕ and ϕ′.
DISCOUNT GOODS CONSUMPTION IN ISLAMIC ECONOMICS PERSPECTIVE
Authors: Armina Sheema Haseena
Published: March 2022

This study aims to analyze discount goods consumption in the view of the Islamic economics perspective. The consumers are attracted to this a lot because of low prices and the scarce bid product however this is impressed a waste of money for consumption and purchase something. This research is a qualitative descriptive with primary data supported by the interview with the purposive method. The informants are female students of the university. The findings of this research are nothing wrong with the discount goods but this tend to make many consumers purchase more product which the orientation of consumption not only about spending money and purchasing a product for personal pleasure but it supposed to spread welfare and happiness through ZISWAF as a tool for charity. The implication of this research that people should be wise to fulfill the needs neither the wants if it is necessary.
MUSLIM COMMUNITY IN GERMANY: CURRENT CHALLENGES AND OPPORTUNITIES
Authors: Meirison Meirison , Yusna Darni
Published: March 2022

A recent study showed that the number of Muslims had increased significantly in Germany since 2015. Many of them still face challenges in terms of employment and training. Religion may be a secondary cause of these challenges, "but it does not hinder integration in general." "We will do that," was the most famous phrase of German Chancellor Angela Merkel, in 2015, referring to her that her country is capable and ready to receive a large number of refugees, when Germany opened its doors to them and received about one million people, most of them from the Middle East, especially Syria. The author conducted a literature study by quoting from various sources as well as using a descriptive and comparative analysis approach, after about six years, the number of Muslims in Germany has become much larger, and the demographic structure has become less homogeneous, according to a recent official study, conducted by the Federal Office for Migration and Refugees (PAMF) at the request of the Islam Conference in Germany and the Federal Ministry of the Interior. However, the growing number of Muslims in Germany came under pressure as their numbers grew. Sometimes due to hatred and incitement from outside and within Germany itself. Cultural differences, especially religion, have become a catalyst for the emergence of such hatred. The number of Muslims continues to increase in line with the increasing efforts in cultural assimilation and the ongoing adjustment of the social environment that has changed the situation, which is expected to be better than the previous situation.
Keefektivan Bahan Ajar Mata Kuliah Statistika Matematika Berbasis Pemecahan Masalah Serta Bernuansa Islami
Authors: Utami Nita Putri
Published: March 2022

Kondisi perkuliahan berhubungan dengan kompetensi dosen, media perkuliahan, sarana dan prasarana perkuliahan. Bahan ajar merupakan salah satu media perkuliahan yang sangat menentukan keberhasilan perkuliahan. sebagai seorang dosen sebaiknya menfasilitasi mahasiswa sedemikian hingga menjadi menarik dalam perkuliahan. Akantetapi kenyataannya dilapangan, masih rendahnya daya tarik mahasiswa dalam perkuliahan. Statistika Matematika  adalah salah satu matakuliah yang sangat penting, artinya  sangat banyak digunakan pada saat telah menjadi guru dan membantu dalam  pembuatan tugas akhir.  Oleh karena itu, seharusnya dosen menfasilitasi dengan memberikan suatu bahan ajar yang berisikan  masalah-masalah matematika yang bernuansa islami. Jadi rumusan masalah pada penelitian ini bagaimana proses dan hasil pengembangan     Bahan Ajar Mata Kuliah Statistika Matematika  Berbasis Pemecahan     Masalah Serta Bernuansa Islami yang valid
KEMAMPUAN PEMAHAMAN KONSEP MATEMATIS MODEL RECIPROCAL TEACHING (RT) DAN MODEL AIR AUDITORY INTELLECTUALY REPETITION (AIR)
Authors: Susanto Andi
Published: March 2022

The purpose of this research was to determine the ability to understand the mathematical concepts of students taught by reciprocal teaching models with an intellectually repetition model in SMP N 6 Kota Solok. This type of research is a quasy experiment with a randomized control group only design. Test instruments the ability to understand mathematical concepts. Based on the test result obtained the average ability to understand the mathematical concepts of students by reciprocal teaching model 81,66 by auditory intellectually repetition model 77,75 and ordinary learning 73,91. Hypothesis testing indicated that the ability to understand the mathematical concepts of students by reciprocal teaching model and the auditory intellectually repetition model were higher than the ordinary learning model. Beside it, it was also concluded that there were difference in the ability to understand mathematical concepts with reciprocal teaching model and auditory intellectually repetition model.
PENINGKATAN HASIL BELAJAR MATEMATIKA SISWA SMA MELALUI PENERAPAN STRATEGI LEARNING TOURNAMENT
Authors: Rabiati Rabiati , Mardika Fitria
Published: March 2022

Penelitian ini merupakan penelitian tindakan kelas (PTK) yang bertujuan untuk meningkatkan hasil belajar matematika siswa dengan menggunakan strategi pembelajaran aktif learning tournament.  Target penelitian ini adalah siswa kelas X pada SMAN 10 Pekanbaru. PTK dilaksanakan dalam 3 siklus yang mana setiap siklusnya terdiri atas tahapan perencanaan, tindakan/observasi, dan refleksi. Instrumen yang digunakan adalah instrument tes formatif yang bertujuan untuk mengukur kemampuan pemahaman konsep matematika pada pokok bahasan logaritma. Tes formatif diberikan pada setiap akhir siklus. Berdasarkan analisis data secara deskriptif kuantitatif diperoleh hasil penelitian berupa peningkatan hasil belajar matematika siswa pada setiap siklusnya. Hasil akhir penelitian menunjukkan bahwa penerapan strategi pembelajaran aktif learning tournament dapat meningkatkan hasil belajar siswa dengan persentase pada siklus I sebesar 67,50 % , siklus II sebesar 75,00 % dan siklus III sebesar 80,00 %.
PENERAPAN MODEL PEMBELAJARAN ADVANCE ORGANIZER TERHADAP KEMAMPUAN BERPIKIR KRITIS MATEMATIS SISWA
Authors: Sujana Asep , Meika Ika , Tiaraswati Tiaraswati
Published: March 2022

Penelitian ini dilatar belakangi oleh rendahnya kemampuan berpikir kritis matematis siswa dalam pembelajaran matematika. Tujuan penelitian ini yaitu untuk mengetahui perbedaan kemampuan berpikir kritis matematis antara siswa yang memperoleh model pembelajaran Advance Organizer dibandingkan dengan siswa yang memperoleh pembelajaran biasa. Penelitian ini dilakukan terhadap siswa kelas XI SMA Mathla’ul Anwar Menes kabupaten Pandeglang, Provinsi Banten. Metode yang digunakan dalam penelitian ini adalah metode Quasi Eksperimental yang berdesain The Nonequivalent Pretest-Posttest Control Group Design. Teknik pengambilan sampel dalam penelitian ini menggunakan teknik Purposive Sampling yaitu kelas XI IIS 1 sebanyak 35 siswa sebagai kelas eksperimen yang mendapatkan pembelajaran matematika dengan model pembelajaran Advance Organizer dan kelas XI IIS 2 sebanyak 35 siswa sebagai kelas kontrol yang memperoleh pembelajaran biasa. Berdasarkan analisis data dan pengujian hipotesis bahwa terdapat perbedaan kemampuan berpikir kritis matematis antara siswa yang memperoleh model pembelajaran Advance Organizer dibandingkan dengan siswa yang memperoleh pembelajaran biasa.
STRATEGI KEPEMIMPINAN ABAD 21: VISIONER, KREATIF, INOVATIF, DAN CERDAS EMOSI
Authors: Isnaini Lailatul
Published: March 2022

The idea of 21st Century leadership goes from the view that leaders must recognize precisely and fully both about themselves and about the conditions and aspirations of the people they lead, the development and the strategic environmental problems encountered in various fields, especially in the field they do, as well as the paradigm And the organizational and management systems in which it plays a role. The leader's responsibility is to provide solutions wisely and precisely on the problems and challenges facing his time, which is done with the people he leads. Organizational leaders occupy a central position in the effort to promote their institutions. Therefore, one of the things that a leader must have is creativity and innovation of his organization, an effort to make positive new breakthroughs that make the organization better, more advanced and ready to face the 21st century. In addition to having a vision and intelligent Intelligently, leaders are also required to have other intelligence in the face of the complexity of the current problems are increasingly difficult to overcome, namely emotional intelligence (EI).
MANAJEMEN SARANA DAN PRASARANA UNTUK MENINGKATKAN MUTU PENDIDIKAN
Authors: Sukatin Sukatin
Published: March 2022

Improving the quality of education is a demand that must be met by every madrasa and schools in the era of globalization. Management of facilities and infrastructure is very important, because with the management of existing facilities and infrastructure in educational institutions will be maintained and their use clear. Management of the planning process, organizing, leadership and control of the efforts of members of the organization by using all organizational resources to achieve the stated goals. Management is a skill to move and control others to achieve predetermined goals. Educational facilities for all equipment, ingredient, and furniture that is directly used in the education process at school. Educational infrastructure is related to all basic equipment that indirectly supports the implementation of the learning process in schools. The emphasis on this understanding is on its nature, the means are direct and the infrastructure is not direct in supporting the learning process. The Head of Madrasah and also representatives of the Facilities and Infrastructure sector have done a good planning, but still there are things that have not been maximized from the plan, in terms of organization, mobilization has been done but in madrasas still less administration staff, and supervision has also been carried out well, while the obstacles faced are lack of infrastructure, lack of maintenance of facilities and infrastructure, funding and planning issues have not been maximized and lack of administrative staff. All managers of educational institutions should pay serious and monitored attention to the management of educational facilities and infrastructure, because educational facilities and means is one of the determining factors for the formation of an effective and efficient quality of education.
MODEL KEPEMIMPINAN DI PONDOK PESANTREN
Authors: Remiswal Remiswal , Hasbi Firqi , Diani Yola Putri
Published: March 2022

Leadership plays an important role in an organization or institution. Leadership does not only play a role in directing and organizing the potential of organizational members through mutually formulated goals. However, leadership also plays a key role in regulating the rhythm of organizational movements, including Islamic boarding schools. The Islamic boarding school is an Islamic educational institution led by a kyai. As an organization, the level of success of education in Islamic boarding schools is very much influenced by the model and style of the leader. The results of the analysis of this study answered that the leadership model of Islamic boarding schools currently has a leadership model that tends to have individual-collective characteristics. It is known that the implementation of leadership in pesantren is still guided by individual kyai. Meanwhile, in another aspect, the Islamic boarding school is under the auspices of a foundation so that collective leadership collaboration is needed.