bluuebunny/crossref_metadata_2025 huggingface dataset:
A Mixed Integer Linear Programming Formulation and Heuristics for Delay-Aware Neural Network Placement Problem in In-Network Learning
Authors: Hara Takanori
Published: April 2024

In-network learning (INL), which is one of the distributed machine learning (ML), enables both learning and inference over a network by deploying small models representing parts of the global neural network (NN) model on the network. The inference and learning speed of INL model depends on the computation and communication cost. Therefore, the small NN models should be properly deployed on the physical network to meet the service requirements. In other words, INL involves an NN placement problem to aim at minimizing the maximum end-to-end delay. In this paper, we formulate this NN placement problem as a mixed integer linear program (MILP) and develop a heuristic algorithm to overcome its computational complexity. Through the numerical experiments, the proposed MILP works well up to 400 physical nodes. However, the MILP cannot output the optimal solution in case of more than 400 physical nodes, due to the time limit or the out of memory. The proposed heuristic algorithm can provide the feasible solution with a shorter computation time against the physical network size at the sacrifice of the solution optimality, compared with the MILP.
Nanostructured nickel hydroxide Ni(OH) 2 for energy storage applications
Authors: Shinde Vijay L. , Pagare Pavan K. , Torane Appasaheb P.
Published: April 2024

The Ni(OH)2 nanosheets were grown on stainless steel substrates by single-step hydrothermal technique at different deposition times and their supercapacitive properties were investigated. Using a variety of characterization measures, the produced films' structural, morphological, chemical compositional, and electrochemical characteristics were examined. The X-ray diffraction data shows the rhombohedral structure of synthesized Ni(OH)2. The scanning electron microscopic (SEM) photographs of the prepared nickel hydroxide film shows a nanosheet-like structure. Brunauer-Emmett-Teller (BET) analyses shows that nanosheet-like structures have a big surface area for optimized sample of 16.015 m2g− 1 with a mesoporous network. An electrochemical supercapacitor properties of nickel hydroxide nanosheets demonstrates well performance as the electrode. They shows a specific capacitance of 109 F/g at a current density of 0.7 mA/cm2, furthermore excellent energy density and power density of 10.55 Wh/kg and 170 W/kg respectively. Additionally, they demonstrats good cycling stability for calculating cyclic voltammetry, with approximately 70.06% of the scan rate being 100 mV/s.
Glasidian; Polyester-based agglomerated stone made from waste glass and obsidian
Authors: ELÇİ Hakan , YEŞILOVA Çetin , Hacımustafaoğlu Ramazan , Özkan İlker
Published: April 2024

Glasidian is an agglomerated stone made by mixing obsidian and used industrial glass fragments with a polyester binder for cladding. This cladding material is created by connecting obsidian and industrial glass particles, which have extremely comparable material qualities, with polyester in a 1:1 ratio and forming a self-compacting a mixture. The colour and design of the agglomerated stone made from fine glass and obsidian aggregate are comparable to those of real stone cladding. It has lower density and porosity than natural stone. Galacidian is extremely resistant to abrasion and has adequate compressive and bending strengths. Its qualities make it suitable for usage as a cladding material in interiors. This study identified an alternate application for industrial waste glass, which has a very poor recycling rate across the country, and obsidian, which is currently underutilized as a raw material.
An Efficient Encoding Mechanism for Digital Microfluidic-based DNA Data Storage Systems
Authors: Pourasadollah Mostafa , Taajobian Maryam , Jahanian Ali
Published: April 2024

Digital data production speeds up dramatically every day, and the need to store extensive data rises consequently. Many storage media are used today, but only a few are capable of the required features in terms of high density, data duration, storage lifetime, and reliability. DNA-based digital data storage systems are one of the new and feature-rich media to store a massive amount of data in a very tiny volume with a strange lifetime. However, building dense and straightforward DNA storage comes with some challenges. Using manual methods to transfer and mix liquids containing DNA molecules makes this storage more error-prone. Moreover, the encoding method of digital data into DNA molecules is very crucial. This paper proposes a novel method for automatic and controllable DNA strand manipulation using a customized Digital Microfluidic Biochip (DMFB) corresponding to the CAD algorithm. Then, we offer a new approach to encoding the digital data into DNA molecules that helps error detection and correction in DNA storage while it brings efficient encoding density. Experimental results show that we can write 1.6 bits on each nucleotide with a 200-base strand which is a good density compared with other methods. In contrast, the encoding method is much simpler and easier to implement.
The effect of masonry buildings' geometrical characteristics on their vulnerability caused by tunneling- induced settlement
Authors: Kolivand Farshad , Daraei Ako
Published: April 2024

Tunnel construction in the urban area is often a challenge due to the presence of masonry buildings. The aim of this study is to investigate the effects of the geometric characteristics of masonry buildings, on the damage caused by tunneling using numerical simulations. The results show that the width of the building is a more important factor in controlling settlement and damage to the building than its length. The analysis of the building's deformation parameters shows that the differential settlements play a greater role in damage to building. Buildings with a width of less than 10 m suffer only minor damage due to small changes in differential settlement. For buildings with a width of more than 10 m and up to 35 m, the differential settlements increase considerably and cause structural damage. The analysis shows that as the width of the building increases, mainly due to a decrease in the stiffness of the foundation, the slope and angular distortion of the foundation increase and consequently the building damage increases. Buildings with a width of less than 10 m suffered only minor damage, while buildings with a width of more than 21 m suffered structural damage. Furthermore, the tilt of the building alone is not a good parameter for assessing building damage. The length of the building has no significant influence on building damage.
Evaluating Drug Interaction Risks: Nirmatrelvir & Ritonavir Combination (PAXLOVID®) with Concomitant Medications in Real-World Clinical Settings
Authors: Zatovkaňuková Petra , Veselý Dalibor , Slíva Jiří
Published: April 2024

Purpose
This research article delves into the battle against the COVID-19 pandemic, focusing on the efficacy and safety of the combination of nirmatrelvir with ritonavir, found in the pharmaceutical product Paxlovid®. The study aims to analyze the potential interactions of commonly prescribed medicinal products with Paxlovid®, shedding light on its utilization in specific medical fields.
Methods
The analysis draws data from the registers of the Institute of Health Information and Statistics of the Czech Republic (IHIS CR) covering 4,078,065 patients diagnosed with COVID-19. The study focuses on 70 ATC groups, identified based on the most commonly prescribed substances and medical specialties. Pharmacological assessments were conducted using the Liverpool checker (LC) and the Summary of Product Characteristics (SPC) for Paxlovid®.
Results
The combination of nirmatrelvir and ritonavir in the treatment of COVID-19 significantly suppresses the progression to severe illness and reduces the viral load of SARS-CoV-2. An interim analysis showed a lower incidence of COVID-19-related hospitalization or death by day 28 in patients receiving the treatment compared to placebo (6.32% difference, p < 0.001).
Conclusion
The study highlights the promising efficacy of nirmatrelvir with ritonavir in early-stage COVID-19 treatment, emphasizing its potential to manage the disease effectively. Although concerns exist about potential drug interactions, particularly due to ritonavir's impact on cytochrome P450, these interactions are manageable. The analysis of concurrent therapies provides valuable insights into the rational use of Paxlovid® in clinical practice, contributing to ongoing efforts to find safe and effective treatments for COVID-19 amidst emerging variants of the virus.
Studies on the transport behavior of sodium nitrate (NaNO 3 ) and ammonium nitrate (NH 4 NO 3 ) in aqueous binary mixture of 2-Butoxyethanol using electrical conductivity at 298.15, 303.15, 308.15, and 313.15 K
Authors: Das Chanchal
Published: April 2024

Transport behavior of sodium nitrate (NaNO3) and ammonium nitrate (NH4NO3) in aqueous binary mixture of 2-butoxyethanol containing 0.20, 0.40 and 0.60 mass fraction of 2-butoxyethanol were studied using electrical conductivity at 298.15, 303.15, 308.15, and 313.15 K. For the analysis of experimental conductance data, the 1978 Fuoss conductance-concentration equation was used. The values of limiting molar conductance (), ionic association constant (KA) and the association diameter (R) were obtained from the analysis. The ionic contributions to the limiting molar conductances were also estimated. The calculated values of KA and R suggest a weak electrostatic ion solvent interaction for these two salts in aqueous binary mixture of 2-butoxyethanol. Besides, they exist as free ions in all the solvents compositions and temperature range covered in this study. Effect of temperature and solvent compositions on the values of association constants and single-ion conductivity of these electrolytes were discussed. The Walden products for the ions show noticeable deviations under varying temperature and solvent composition.
Hyaluronic acid combined with Centella asiatica extract improve skin barrier function and alleviate inflammatory damage via JAK/STAT3 signaling pathway
Authors: Shi Hong-yu , Liu Qiang , Du Shuai , Zhang Mei-xia , Li Qu-quan , Yang Zhen-bang , Lin Pei
Published: April 2024

Objective
Psoriasis, as a chronic inflammatory skin disease, has complex pathogenesis, stubborn condition and high recurrence rate. Centella asiatica (L.) Urban (CA) is one of the commonly used Chinese herbal medicines in dermatology, which has multiple pharmacological activities such as promoting wound healing, anti-cell proliferation and anti-inflammation. Hyaluronic acid (HA) has become an excellent moisturizing ingredient and is widely used in skin care products. This study aims to explore the effects and mechanism of HA combined with CA on skin inflammatory injury and provide experimental basis for the future application research of HA and CA in inflammatory skin diseases.
Methods
In this study, the skin barrier repair function and the mechanisms of HA combined with CA were evaluated. The expressions of inflammatory factors and barrier related factors were detected in LPS-induced HaCaT cells. The effects on the migration and angiogenesis ability were analyzed in VEGF- induced HUVECs.
Results
HA with different molecular weights increased the contents of GSH and SOD in LPS-induced HaCaT cells, eliminated free radicals, reduced the production of ROS, and inhibited cell oxidative stress. Among them, HA with molecular weight of 6100Da was the best, followed by 1220KDa HA. It was found that the molecular weight of 1220KDa HA effectively inhibited IFN-γ mRNA level, increase the content of AQP3 and FLG in cells. Mechanism research showed that HA inhibited inflammation was related to block the transduction of NF-κB and JAK/STAT3 pathways. Meanwhile, 1220KDa HA (2 mg/mL) combined with ethyl acetate of CA (CAE, 25 µg/mL) could effectively inhibit the expression of MMP-1 in LPS-induced HaCaT cells, increase the expression of skin barrier related proteins AQP3 and FLG, and reduce the secretion of IL-17. HA combined with CAE enhanced the inhibition of NF-κB and JAK/STAT3 pathways, improving the inhibitory effects of CAE on IFN-γ and IL-6. In addition, after the intervention of HA combined with CAE, the migration and the angiogenesis abilities of VEGF-induced HUVEC cells were decreased.
Conclusion
HA combined with CAE can reduce release of inflammatory factors and improve the function of skin barrier via the inhibition of NF-κB and JAK/STAT3 pathways, alleviating psoriasis like inflammatory damage.
Podoplanin depletion in tonsil-derived mesenchymal stem cells induces cellular senescence via regulation of the p16Ink4a/Rb pathway
Authors: Kim Ha Yeong , Kim Han Su
Published: April 2024

Background
Mesenchymal stem cells (MSCs) are widely used in the development of therapeutic tools in regenerative medicine. However, their quality decreases during in vitro expansion because of heterogeneity and acquired cellular senescence. We investigated the potential role of podoplanin (PDPN) in minimizing cellular senescence and maintaining the stemness of tonsil-derived MSCs (TMSCs).
Methods
TMSCs were isolated from human tonsil tissues using an enzymatic method, expanded, and divided into two groups: early-passaged TMSCs, which were cultured for 3–7 passages, and late-passaged TMSCs, which were passaged more than 15 times. The TMSCs were evaluated for cellular senescence and MSC characteristics, and PDPN-positive and -negative cells were identified by fluorescence-activated cell sorting. In addition, MSC features were assessed in siRNA-mediated PDPN-depleted TMSCs.
Results
TMSCs, when passaged more than 15 times and becoming senescent, exhibited reduced proliferative rates, telomere length, pluripotency marker (NANOG, OCT4, and SOX2) expression, and tri-lineage differentiation potential (adipogenesis, chondrogenesis, or osteogenesis) compared to cells passaged less than five times. Furthermore, PDPN protein levels significantly decreased in a passage-dependent manner. PDPN-positive cells maintained their stemness characteristics, such as MSC-specific surface antigen (CD14, CD34, CD45, CD73, CD90, and CD105) and pluripotency marker expression, and exhibited higher tri-lineage differentiation potential than PDPN-negative cells. SiRNA-mediated silencing of PDPN led to decreased cell-cycle progression, proliferation, and migration, indicating the significance of PDPN as a preliminary senescence-related factor. These reductions directly contributed to the induction of cellular senescence via p16Ink4a/Rb pathway activation.
Conclusion
PDPN may serve as a novel biomarker to mitigate cellular senescence in the clinical application of MSCs.
Exploring the Role of Key Gene PTTG1 in Clear Cell Renal Carcinoma Based on Bioinformatics Analysis and In-vitro Cell Experiments
Authors: Guan Li-hui , Wu Yu-dong
Published: April 2024

Background: This study aimed at exploring the expression characteristics and functional roles of PTTG1 in ccRCC by bioinformatics analysis and in-vitro experiments, as well as its potential to be a new type of therapeutic target.
Methods: TCGA-KIRC data and relevant information of the samples were obtained from UCSC Xena. Data of GSE66271, GSE168845 and GSE105261 were obtained from the GEO database. Differentially expressed genes were screened based on TCGA-KIRC and GSE168845 and the protein-protein interaction network was constructed. The risk regression model was constructed by Lasso regression and the key prognostic genes were obtained by combining immune infiltration and pathway enrichment analysis. Genes and proteins were quantified using RT-qPCR and western blot. MTT assay was used to detect the vitality of cells. Cell apoptosis and cell cycle were detected by flow cytometry. The comet assay was adopted to detect the damage degree of cell DNA.
Results: Six significant DDR-relevant prognostic genes (CCNA2, CDC45, CTLA4, FOXM1, PLK1, and PTTG1) were obtained. A risk model was constructed using Lasso regression, and it was verified in multiple data sets that the renal cell carcinoma group had a higher risk score and was mainly enriched in multiple T cell-related pathways. Immune infiltration results showed that CTLA4 was significantly positively correlated to T cells CD8. Besides, PTTG1 was negatively correlated to T cells CD4 memory resting, but remarkably positively correlated with both T cells CD8 and T cells regulatory. Compared with normal renal proximal tubular epithelial cells, the protein expression of PTTG1 was up-regulated at both mRNA and protein levels in ccRCC tissues. PTTG1could notably promote the proliferation of 786-O cells, and significantly inhibited apoptosis, cycle arrest and DNA damage of 786-O cells.
Conclusion: PTTG1 may play a carcinogenic role by promoting the proliferation of ccRCC cells and inhibiting apoptosis. PTTG1 is expected to become a potential diagnostic and prognostic biomarker as well as an immunotherapy target for ccRCC.
Rolling-crew concurrent vibration platform – vibration characteristics and motion of granular material in the horizontal plane
Authors: Poćwiardowski Wojciech
Published: April 2024

The paper presents the characteristics of the rolling-screw vibration system with two vibrators. Theoretical dependencies for this drive causing circumferential vibrations on the OXY plane and vertical vibrations on the OZ axis were discussed. The phenomenon of self-synchronization occurring in this system has been described. The dependence of the peripheral velocity of the material on the size of the throw was determined. The dynamics of the work of the rolling-screw vibration platform with two vibrators, working in a concurrent system, is influenced by the value of the force forcing the vibrations and the angle of inclination of the vibrators in relation to the horizontal. The obtained results will allow to undertake optimization studies of the operation of the vibrating platform and to find its further applications, which will allow for the full use of the potential of the rolling-screw vibrating device in the industry.
Identification of graphite with perfect rhombohedral stacking by electronic Raman scattering
Authors: Nemes-Incze Péter , Pálinkás András , Márity Krisztián , Kandrai Konrád , Tajkov Zoltán , Gmitra Martin , Vancsó Péter , Tapasztó Levente
Published: April 2024

Rhombohedral graphite (RG) shows strong correlations in its topological flat band and is pivotal for exploring emergent, correlated electronic phenomena. One key advantage is the enhancement of electronic interactions with the increase in the number of rhombohedrally stacked graphene layers. Increasing thickness also leads to an exponential increase in the number of stacking faults, necessitating a precise method to identify flawless rhombohedral stacking. Overcoming this challenge is difficult because the established technique for stacking sequence identification, based on the Raman 2D peak, fails in thick RG samples. We demonstrate that the strong layer dependence of the band structure can be harnessed to identify RG without stacking faults, or alternatively, to detect their presence. For thicknesses ranging from 3 to 12 layers, we show that each perfect RG structure presents distinctive peak positions in electronic Raman scattering (ERS). This measurement can be carried out using a conventional confocal Raman spectrometer at room temperature, using visible excitation wavelengths. Consequently, this overcomes the identification challenge by providing a simple and fast optical measurement technique, thereby helping to establish RG as a platform for studying strong correlations in one of the simplest crystals possible.
CLANet: A Contrastive Learning based Attention Network for Image Forgery Detection
Authors: Guo Ying , Jin Yangqi Jin Yangqi , Tian Chang , Liu Jie
Published: April 2024

Digital image forgery poses a potential security threat to various industries and has attracted widespread attention. Most deep learning-based models for image forgery detection depend on edge artifacts or residual compression traces. These models utilize the adaptability of convolutional neural networks to automatically extract forgery features. However, certain forgery techniques can accurately mimic the features of natural images or alter specific features to mask forgery, thereby making it difficult for the model to accurately detect tampered images. This paper introduces a wider and deeper architecture with dual-stream and multi-scales, and subsequently builds a contrastive learning-based algorithm for detecting image forgery. The algorithm fully utilizes low-level?s details and high-level semantics by a multi-scale attention module, as well as pixel-domain contents and frequency-domain edges by a dual-stream fusion module, to obtain a more comprehensive feature representation. Each image is devoted to learning a more discriminative feature representation via contrastive learning, which is achieved by minimizing the distance between forgery samples and maximizing the distance between forgery and non-forgery samples. Furthermore, this paper proposes a novel approach to addressing overfitting during model training by incorporating a constraint function into the loss function.
Interpolation for neural network operators activated with a generalized logistic-type function
Authors: Uyan Hande , Aslan Abdullah Ozan , Karateke Seda , Büyükyazıcı İbrahim
Published: April 2024

This paper defines a family of neural network interpolation operators. The first derivative of generalized logistic-type functions is considered as an density function. Using the first-order uniform approximation theorem for continuous functions defined on the finite intervals, the interpolation properties of these operators are presented. A Kantorovich-type variant of the operators Fna,ε is also introduced. The approximation of Kantorovich-type operators in LP spaces with 1 ≤ p ≤ ∞ is studied. Further, different combinations of the parameters of our generalized logistic-type activation function θs,a are examined to see which parameter values might give us a more efficient activation function. By choosing suitable parameters for the operator Fna,ε and the Kantorovich variant of the operator Fna,ε, the approximation of various function examples is studied.
Abordajes interdisciplinarios de experiencias sobre violencia social, pandemia y adolescencia
Authors:   Universidad Católica Luis Amigó, Viveros Chavarría Edison Francisco
Published: April 2024

Esta compilación hace parte de la Colección Individuo, Familia y Sociedad. Lleva por título Abordajes interdisciplinarios de experiencias sobre violencia social, pandemia y adolescencia y no es monotemática. Aquí se divulgan escritos de estudiantes, graduados y docentes de la Facultad de Ciencias Sociales, Salud y Bienestar de la Universidad Católica Luis Amigó, textos que son el efecto de procesos deliberativos llevados a cabo en ambientes para la interacción intelectual y también son consecuencia de diversas estrategias que buscaban estimular la escritura. En ese sentido, el lector hallará una diversidad de perspectivas propias de las Ciencias Sociales, textos diversos, múltiples, pero sin la inflexibilidad de la unidad rígida.
LAWFUL DEFENSE VS. NECESSARY SELF-DEFENSE: ANALYSIS OF INNOVATIONS IN THE NEW CRIMINAL CODE OF UKRAINE PROJECT
Authors: Mykhailichenko Tetiana O. , Zabuha Yuliia Yu.
Published: April 2024

Today, the process of building our state continues, which is also accompanied by the approximation of Ukrainian criminal legislation to the European one. In particular, the draft of the new Criminal Code of Ukraine is currently being discussed. The article analyzed the provisions of the draft of the new Criminal Code of Ukraine, devoted to the individual's right to protection. The authors laid numerous innovations in the provisions on necessary defense (legitimate defense). Therefore, the purpose of this article is to identify the advantages and disadvantages of the provisions of Art. 2.9.2 «Legitimate defense» in the draft of the new Criminal Code of Ukraine, as well as the provision of proposals to eliminate the identified problems. Arguments are presented regarding the expediency of changing the title of the article, expanding and clarifying special types of legal protection, in particular, in cases of protection against: 1) illegal encroachment of a person who used a weapon, a dangerous object or another object that has the properties of a weapon or a dangerous object, 2) an illegal invasion of housing or other property or 3) rape. At the same time, it was emphasized the need for correct use of terms within the entire Draft and the need to follow a unified approach to formulating grounds for legitimate defense.
Treatment of Infertility through the Qur'an: Shifting the Function of al-Syifa' from Spiritual Disease Treatment to Physical Medicine
Authors: Ichwan Mohammad Nor , Rohmah Nihayatur
Published: April 2024

Al-Qur’an, besides proclaiming itself as a guide for the man (huda li al-nas), also serves as a cure or healer (shifa') against all kinds of diseases, especially spiritual conditions. In the Community of Therapy Sky Line Two With Prayer, the Qur'an serves as a medium of infertility treatment. Infertility occurs when a husband and wife do not have children, even though they are sexually active. Besides being caused by medical factors, infertility is also caused by non-medical factors, such as genie or magic disorders. This article aims to elaborate and, at the same time, prove the success of infertility treatment through the medium of Qur'anic verses carried out by Therapy Sky Line Two With Prayer. Methodologically, this article uses field research whose primary sources are obtained through observation, structured interviews, and documentation. The collected data was then analyzed using a phenomenological approach. The findings of this article show that the Qur'an can not only cure spiritual diseases but can also be used as a medium to treat infertility. This article also found that the verses of the Qur'an recited to people with infertility can make their hearts calm, more pleased with His decrees, and also more grateful for the blessings He has given. This attitude is a fundamental thing that is needed for those who have not been blessed with offspring. Hence, they feel confident that chanting the verses of the Qur'an can stimulate people with infertility and make them pregnant and have the desired offspring.
Current Directions of Methodological Support for Teachers in the Implementation of Online Learning for Schoolchildren
Authors: Sartakov Igor' , Slaveninova Natal'ya , Chikova Ol'ga
Published: April 2024

The authors analyzed scientific and methodological publications on the methods of organizing online learning to identify the current directions in methodological support. These directions included the tools that provide digital communication, multimedia presentation, exchange of methodological materials, video hosting sites, and online tests. A survey of 58 teachers from the Novosibirsk and Sverdlovsk regions revealed their ideas about methodological support for online teaching. The research showed almost no correlation between the responses and the respondents’ gender, age, profile training, teaching experience, online teaching experience, etc. The respondents needed methodological support in mastering multifunctional communication tools, e.g., Microsoft Teams or Discord; the forms of presentation of multimedia graphic content as charts, infographics, intelligence maps, etc.; cloud services for the exchange of methodological materials; special forms to create online tests, e.g., Google Forms, WEBanketa, Menti.com. Most teachers demonstrated a good understanding of the procedure for using materials downloaded from video hosting sites as part of online lessons. The results of the study are relevant for Russian schools and determine the directions of additional training for teachers as providers of digital academic environment.
Evaluation of the Properties of Fiber-Reinforced Pervious Concrete Pavement Incorporating Glass Powder and Kaolin
Authors: Awolusi Temitope , Aluko Oluwaseun , Oguntayo Daniel , Ajayi Precious , Tohme Christelle , Azab Marc
Published: April 2024

Introduction

Pervious concrete has been significantly helpful in water quality control and preventing surface runoff through easy infiltration and percolation of water. A developing country such as Nigeria is prone to flooding, and promoting pervious concrete will significantly mitigate this problem. However, structural issues are associated with pervious concrete, such as weak bonds and durability concerns due to the infiltration of deleterious materials.

Methods

The study incorporates glass powder, kaolin and sisal fiber to improve the performance of pervious concrete. Glass powder and Kaolin were incorporated as supplementary cementitious materials at 0, 10, and 20% and sisal fiber-reinforced at 0, 1, and 2%. The pervious concrete mixtures at 28 days were subjected to water absorption, permeable voids, and compressive and split tensile strengths.

Results

The results indicate that the fiber-reinforced pervious concrete with glass powder and Kaolin met the strength requirements. However, the strength resulting from incorporating Kaolin is much higher; hence, Kaolin is preferable in times of strength in fiber-reinforced pervious concrete. Nonetheless, an equal 10%-10% combined use of kaolin and glass powder and 1% sisal fiber proves an alternative to obtaining strength values within ACI specification.

Conclusion

These research findings will enhance the performance of pervious concrete, an eco-friendly and responsible approach to managing rainwater.
The Strategic Effort to Ensure Successful Breastfeeding Practice in the Workplace: An Indonesian Expert Opinion
Authors: Basrowi Ray Wagiu , Darus Febriansyah , Partiwi I Gusti Ayu Nyoman , Sutanto Luciana B. , Sulistomo Astrid , Soemarko Dewi Sumaryani , Wasito Erika , Sundjaya Tonny , Pratiwi Dessy
Published: April 2024

Background

Breastfeeding has benefits for both the child and the mother. However, breastfeeding can be a challenge for working mothers due to inadequate time and space for expressing breastmilk, employer perceptions of reduced productivity, regulations prohibiting children in the workplace, and the lack of childcare close to the workplace.

Methodology

The experts from different backgrounds were invited to provide their views on this matter. This report summarizes the discussion of multidisciplinary experts on the recommendations about breastfeeding practices for mothers and the workplace.

Results

Improving education and knowledge, implementing a lactation promotion model, seeking information, and making plans and arrangements are recommended for successful breastfeeding practices.

Conclusion

The aspects of the lactation promotion model can be the key to successful breastfeeding for working mothers.
Pengaruh Konsentrasi Ecoenzyme dan Pupuk NPK pada Pertumbuhan dan Pembungaan Tanaman Begonia Lilin (Begonia Semperflorens)
Authors: Nadeak Nathalia Ully , Setiawan adi , Sitawati Sitawati
Published: April 2024

Begonia lilin merupakan salah satu tanaman hias yang diperjualbelikan dan banyak diminati masyarakat karena memiliki keindahan pada bunganya dan dapat berbunga sepanjang tahun. Penggunaan pupuk NPK yang berlebihan dapat mengganggu pertumbuhan tanaman sehingga dengan diberikan ecoenzyme yang berasal dari limbah organik dapat mengurangi penggunaan pupuk NPK. Tujuan penelitian ini adalah untuk mempelajari interaksi antara konsentrasi ecoenzyme dan pupuk NPK pada pertumbuhan dan pembungaan tanaman begonia lilin (Begonia semperflorens). Penelitian ini dilakukan pada bulan Februari hingga April 2023 berlokasi di VNT Garden, Desa Sidomulyo, Kota Batu, Jawa Timur. Penelitian ini menggunakan percobaan faktorial dengan Rancangan Acak Kelompok (RAK) yang terdiri dari dua faktor yakni, konsentrasi ecoenzyme yang terdiri dari empat taraf, yaitu 0 ml.l-1, 15 ml.l-1, 30 ml.l-1 dan 45 ml.l-1. Faktor kedua yaitu konsentrasi pupuk NPK yang terdiri dari tiga taraf yaitu 4 g.l-1, 6 g.l-1 dan 8 g.l-1. Data yang diperoleh dianalisis menggunakan Analysis of Variance (ANOVA) pada taraf 5% dan apabila berpengaruh nyata dilakukan uji lanjut Beda Nyata Jujur (BNJ) pada taraf 5%. Hasil penelitian menunjukan bahwa pemberian ecoenzyme 45 ml.l-1 dengan NPK 4 g.l-1 berinteraksi meningkatkan pertumbuhan dan pembungaan tanaman begonia lilin seperti panjang tanaman, jumlah daun, luas daun, jumlah cabang, lebar kanopi, indeks klorofil, bobot segar total tanaman, jumlah cluster bunga, jumlah bunga per cluster, dan menurunkan rasio jumlah daun dan jumlah bunga dibandingkan 0 ml.l-1 ecoenzyme dan pupuk NPK 8 g.l-1 (efisiensi 50%). Namun, pemberian ecoenzyme 45 ml.l-1 dengan NPK 4 g.l-1 memperlambat waktu muncul bunga dibandingkan kontrol.
Kepemimpinan Jawa Arek di Desa Hulurejo dalam Perspektif Kewirausahaan Politik
Authors:   FISIP Universitas Brawijaya , Indonesia, Sadewa Bayu , Sobari Wawan , Haboddin Muhtar
Published: April 2024

Penelitian studi kasus kausalitas ini bertujuan untuk mengeksplorasi bagaimana praktik kewirausahaan politik dengan mempertimbangkan variabel kebudayaan dalam menjalankan strategi sebagai seorang usahawan politik dimana studi ini belum banyak didiskusikan dalam riset akademis. Kewirausahaan politik menurut pandangan Petridou (2016) dibagi menjadi empat aspek utama, yakni Who, How, Where dan Impact. Berbeda dengan teori yang digunakan, penelitian ini berusaha untuk menjelaskan aspek how dari sisi kebudayaan. Dua indikator penting yang dimuat dari aspek how adalah interaksi antar aktor dan strategi seorang usahawan politik akan dielaborasikan dengan kebudayaan jawa arek. Kebudayaan Jawa Arek yang dikenal dengan karakter lugas, blak-blakan, hingga bondho nekat akan mewarnai terhadap bagaimana kepemimpinan Kepala Desa Hulurejo yang menjadi subjek penelitian. Penelitian ini menunjukkan bahwa filosofi jawa arek yang diimplementasikan dalam strategi kewirausahaan politik kepala desa mampu untuk menjadi solusi terkait dengan berbagai permasalahan yang ada di masyarakat, hal ini didasarkan pada pola komunikasi yang cair dan mampu mengakomodasi kepentingan masyarakat. Hasil penelitian ini juga menunjukkan bahwa dalam praktik kewirausahaan ini juga mengandung dua cabang utama kewirausahaan politik yakni ekonomi politik dalam hal relokasi sumber daya dan perubahan kebijakan. Fenomena penyaluran BLTDD pandemi mendukung pernyataan Petridou (2016) tentang imbalan beberapa jenis keuntungan politik dalam proses relokasi sumber daya.
The Effectiveness of Performance of E-Office System in Tanzania's Public Institutions
Authors:   The University of Dodoma, Tanzania,, Kanyengele Abdallah Sophia , A. Kopoka Peter
Published: April 2024

The main objective of this study was to examine the effectiveness of the performance of the e-office system in Tanzania's Public Institutions at the President's Office of Public Service Management and Good Governance (POPSMGG). Specifically, the study determined the extent to which the e-office system is used at PO PSMGG, assessed the impact of using the e-office system at PO PSMGG, and examined the challenges faced in using the e-office system at PO PSMGG. The study adopted a cross-sectional research design. A total of 132 participants participated in this study, equal to an 86.8% response rate. The Resource-Based View theory guided the study. The study employed questionnaires and interview methods to collect data. The findings revealed that the majority of respondents, 58%, said they use e-office daily. The study results indicated that most respondents, 90%, agreed that the e-office system improves customer service. The findings revealed that most of the respondents, 71% disagreed with the statement that the lack of adequate ICT infrastructure affects the POPSMGG to use the e-office system. Also, the study revealed that most of the respondents, 59% disagreed with the statement that the most significant barrier to using the e-office system is a lack of willingness to use the system. Generally, the overall results regarding the challenges experienced when using the e-office system showed that most respondents indicated issues such as unreliable power supply, security concerns, and technology dependency. The study recommends that the government integrate the e-office system with other government systems to facilitate data and information sharing.
The Solutions in Health Analytics for Rural Equity Across the Northwest (SHARE-NW) Dashboard for Health Equity in Rural Public Health: Usability Evaluation
Authors: Heitkemper Elizabeth , Hulse Scott , Bekemeier Betty , Schultz Melinda , Whitman Greg , Turner Anne M
Published: April 2024

Background

Given the dearth of resources to support rural public health practice, the solutions in health analytics for rural equity across the northwest dashboard (SHAREdash) was created to support rural county public health departments in northwestern United States with accessible and relevant data to identify and address health disparities in their jurisdictions. To ensure the development of useful dashboards, assessment of usability should occur at multiple stages throughout the system development life cycle. SHAREdash was refined via user-centered design methods, and upon completion, it is critical to evaluate the usability of SHAREdash.

Objective

This study aims to evaluate the usability of SHAREdash based on the system development lifecycle stage 3 evaluation goals of efficiency, satisfaction, and validity.

Methods

Public health professionals from rural health departments from Washington, Idaho, Oregon, and Alaska were enrolled in the usability study from January to April 2022. The web-based evaluation consisted of 2 think-aloud tasks and a semistructured qualitative interview. Think-aloud tasks assessed efficiency and effectiveness, and the interview investigated satisfaction and overall usability. Verbatim transcripts from the tasks and interviews were analyzed using directed content analysis.

Results

Of the 9 participants, all were female and most worked at a local health department (7/9, 78%). A mean of 10.1 (SD 1.4) clicks for task 1 (could be completed in 7 clicks) and 11.4 (SD 2.0) clicks for task 2 (could be completed in 9 clicks) were recorded. For both tasks, most participants required no prompting—89% (n=8) participants for task 1 and 67% (n=6) participants for task 2, respectively. For effectiveness, all participants were able to complete each task accurately and comprehensively. Overall, the participants were highly satisfied with the dashboard with everyone remarking on the utility of using it to support their work, particularly to compare their jurisdiction to others. Finally, half of the participants stated that the ability to share the graphs from the dashboard would be “extremely useful” for their work. The only aspect of the dashboard cited as problematic is the amount of missing data that was present, which was a constraint of the data available about rural jurisdictions.

Conclusions

Think-aloud tasks showed that the SHAREdash allows users to complete tasks efficiently. Overall, participants reported being very satisfied with the dashboard and provided multiple ways they planned to use it to support their work. The main usability issue identified was the lack of available data indicating the importance of addressing the ongoing issues of missing and fragmented public health data, particularly for rural communities.
Endocrine dysfunction in the pathogenesis of combat surgical trauma and post-traumatic stress disorder (scientific review)
Authors: Usenko O.Yu. , Khomenko I.P. , Kovalenko A.E. , Nehoduiko V.V. , Misyura K.V. , Zabronsky A.V.
Published: April 2024

The modern hostilities have created the unique challenges for medical, surgical and rehabilitation assistance to people liable for military service who have sustained injuries in the battle conditions. The experience of providing medical care for participants of modern military operations has shown that endocrine dysfunction is a leading pathogenetic link that affects the human body in combat surgical trauma and post-traumatic stress disorders. The main pathogenetic mechanism of trauma and post-traumatic stress disorders is associated with dysfunction of the hypothalamic-pituitary-adrenal axis. Hormones such as cortisol, dehydroepiandrosterone, adrenaline and noradrenaline are involved in the neuroendocrine mechanisms of stress development. These hormones regulate and control the stress response, reflecting the stages of its course and the adaptive capacities of the organism. Dysfunction of the hypothalamic-pituitary-thyroid axis has a significant importance in the regulation of both acute and chronic stress accompanied by the clinical development of various thyroid disorders such as hyperthyroidism, Graves’ disease, autoimmune thyroidopathies and nodular transformation. Therefore, the practical significance lies in the clinical studying the key indicators of pituitary-adrenal and pituitary-thyroid function, monitoring the function of the adrenal glands and the thyroid. Correction of these disorders, the treatment and rehabilitation of patients with combat-related traumatic injuries should be carried out with specialized endocrinological assistance. This approach will be relevant for military medicine in Ukraine in the following years.
Effect of use Organic Fertilizer on Yield component yield and quality of Hatri 10, Hatri 475 rice on Chau Phu a Giang, Vietnam
Authors: Nguyen Phuoc Trong , Bui Hieu Chi , Nguyen Ngoc Thanh Le , Nguyen Lang Thi
Published: April 2024

The present study aimed to determine the effect of different organic and inorganic source of fertilizers on growth and performance of rice. The experiment was conducted at locations: Chau Phu A Giang province with two varieties of improved rice with HATRI 10 and HATRI 475. Each experiment has seven treatments. Treatments included a combination of organic and inorganic nutrients at seven rates (F1: 80-40-40+ organic manures 10 t ha-1; F2: 60-40-40+ organic manures 10 t ha-1; F3: 40+40+40+ organic manures 10 t ha-1; F4: 20-40-40+ organic manures 10 t ha-1. F5: only organic manures 12 t ha-1; F6: control no dose of NPK; F7: farmers used: 120-40-60+ organic manures 12 t ha-1). The experiment is arranged on the farmer's field, a split-plot in a randomized complete block design with three replications. Treatments produced significant results for plant height. Panicle length and grain yield but thousands of grains weight was not significant. Result showed that application of half of recommended 60-40-40 + organic manures 10 t ha-1 produced significantly higher value for grain yield and good for quality improve variety.
NUEVOS REGISTROS DISTRIBUCIONALES DE ANFIBIOS Y REPTILES EN EL ESTADO DE OAXACA, MÉXICO
Authors: García-Padilla Elí , Villalobos Juárez Ivan , Bautista-Bautista Leonel , Méndez Celestino , Torres-Barragán Carlos Augusto , Tomás-López Cristian , López-Jiménez Bartolomé , Martínez-Cruz José Manuel , Sosa-Reyes Martín
Published: April 2024

Documentamos formalmente nuevos registros de distribución dignos de mención para la entidad de Oaxaca en el sur de México, incluidas las ranas arborícolas Charadrahyla chaneque, Sarcohyla labeculata, S. hazelae, S. celata y Triprion spinosus. La serpiente falsa ojo de gato Tantalophis discolor, la serpiente cordelilla Imantodes gemmistratus, la serpiente de coral Micrurus elegans y las víboras Agkistrodon bilineatus, Cerrophidion petlalcalensis, Ophryacus undulatus y Porthidum dunni. Algunos registros representan el redescubrimiento de la especie en varias décadas.
NOTES ON THE DIET OF THE GROUD SNAKES Pliocercus euryzonus AND Urotheca guentheri (SQUAMATA: DIPSADIDAE) FROM COSTA RICA
Authors: Abarca Alvarado Juan Gabriel , Varela-Soto Donald , Gómez-Campos Claudia , O’Donnell Matthew , Guimaraes Sales Naiara
Published: April 2024

We report observations of the diet of two species of terrestrial snakes: Pliocercus euryzonus was observed feeding on an egg mass, probably from of Agalychnis callidryas, while Urotheca guentheri was observed feeding on the snake Ninia maculata. These dietary items had not been reported for these snakes, so they represent an important contribution to the natural history of these two species.
The Virulence Genes of Sensitive Strain Pseudomonas aeruginosa Causing Nosocomial Outbreaks
Authors: Rosli Nabila Farina , Abdul-Aziz Aziyah , Adnan Ariza , Mohd. Nawi Siti Farah Alwani
Published: April 2024

Pseudomonas aeruginosa is an opportunistic pathogen which is commonly associated with healthcare associated infection. They possess multiple pathogenic factors which play a role in causing invasive infections such as surgical site infection, pneumonia, and blood stream infection. There were two hospital outbreaks caused by sensitive strains P. aeruginosa between 2016 and 2017 involving 17 patients. The outbreak investigation by Pulsed Field Gel Electrophoresis (PFGE) revealed seven clonally related P. aeruginosa strains (A-G). This study aims to determine the virulence factors acquired by the P. aeruginosa isolates and describe the clinical outcome of the patients. Seventeen P. aeruginosa isolates from the stocked collection were retrieved for six virulence genes, namely ToxA, ExoS, LasI, LasB, OprI, and OprL by PCR. Ten out of 17 of the P. aeruginosa isolates were able to revive. The ExoS, LasI, LasB, OprI, and OprL genes, respectively, were detected in all isolates, while ToxA gene was detected in six isolates which belonged to clone A (one isolate) and clone C (five isolates). The isolate from clone A caused pneumonia and isolates from clone C caused surgical site infections which led to disseminated infections and death. The presence of multiple virulence genes in these P. aeruginosa isolates may have contributed to the invasiveness, and the outcome of the infection. More studies with a larger number of patients will give a better insight regarding the actual role of these genes in different clinical manifestations caused by sensitive strain P. aeruginosa.
Influence of Object Physical Properties Instability on Edge Current Method Sensitivity
Authors: Vlasov K.V. , Bobrov A.L.
Published: April 2024

The article contains results of a study of the eddy current transducer signal parameters from artificial defects against the background of the influence of stray parameters simulated on specially manufactured samples exposed to various external influences. The authors studied the added voltage change of eddy current prob depending on factors affecting the electromagnetic properties of steels. The results of the study were the determination of optimal excitation parameters and threshold values for discrimination levels of phase, amplitude and dynamic parameters when detuning from stray factors. The authors modeled stray parameters of eddy current testing in the form of temperature effects, effects of chemical reagents and plastic deformation of the surface layer. The researchers assessed the distribution of the temperature field, the time of chemical reactions and the composition of the reagents, as well as the geometric parameters of the deformable surface layer of the samples and their effect on eddy current prob added voltage. For the research, artificial defects were made in the form of thin cuts with an opening width of 0.2 mm, located in the stray parameter zone. The geometric dimensions of artificial defects were determined by the requirements for the amplitude of the transducer signals, which should not exceed the change in amplitude under the influence of a stray parameter on the time base, relative to the zero-value installed in the sample area not subject to the influence of external factors. The obtained results of the hodograph analysis when scanning with a clamp-on eddy current transducer made it possible to propose recommendations for detuning from stray parameters of various nature. This was done in order to increase the detectability of defects on objects with significant heterogeneity of the surface structure in the eddy current testing zones.