bluuebunny/crossref_metadata_2025 huggingface dataset:
Revealing the Photochemical Pathways of Nitrate in Water through First-Principles Simulations
Authors: Chan Kam-Tung , Berrens Margaret , Chen Zekun , McCurdy C. William , Anastasio Cort , Donadio Davide
Published: January 2025

Nitrate anion (NO3-) is a ubiquitous species in aqueous phases in the environment, including atmospheric particles, aerosol droplets, surface waters, and snow. The photolysis of nitrate is a 'renoxification' process, which converts \nitrate solvated in water or deposited on surfaces back into NOx to the atmosphere. Nitrate photolysis under environmental conditions can follow two channels: (1) NO2 and O-; (2) nitrite and O. Despite the well-studied macroscopic kinetics of the two channels, the microscopic picture of the photolysis still needs to be explored. Furthermore, previous experiments have shown that nitrate photolysis in aqueous solutions has a low quantum yield of ~1% leading to a solvation cage effect hypothesis. A previous theoretical study has indicated that the low quantum yield may be due to the direct spin-forbidden absorption of \nitrate to its triplet state. Here, we employ first-principles molecular dynamics simulations at the level of hybrid DFT with enhanced sampling to explore the two channels in an aqueous solution to unravel the atomistic and electronic structure details of the photolysis, as well as investigate the causes of its low quantum yield under a solvation environment. The direct spin-forbidden absorption to T1 state is viable through spin-orbit coupling and is ~15 times weaker than the spin-allowed absorption to S1 state. A solvation cage complex is identified as a metastable state that requires additional thermal energy to complete the dissociation of the N-O bond at the triplet state. This metastable state allows the photo fragments to recombine or deactivate through non-radiative processes. Our simulations also qualitatively explain the temperature dependence of the two channels observed in experiments based on the rearrangement of H-bonds. This work provides a novel molecular picture illustrating the significantly low quantum yield and temperature dependence of nitrate photolysis under environmental conditions and a starting point for future studies of environmental nitrate photochemistry.
Techno-economic Impact of Incineration-Based Waste to Energy Generation Technology in Bangladesh: A Short Review and A Case Study
Authors: Hossain Mohammad Masrur , Shahriar Tanvir , Inan Md. Navid , Habib M. Ahsan , Hasanuzzaman M. , Hossain Mohammad Mehran
Published: January 2025

This study evaluates the feasibility of a municipal solid waste incineration-based power generation system in Dhaka, Bangladesh, addressing critical issues of waste management and energy deficits driven by rapid urbanization. A 10 MW waste-to-energy facility operating at 22.5% efficiency was analyzed using key economic metrics, including Net Present Value (NPV), Payback Period, Internal Rate of Return (IRR), Modified Internal Rate of Return (MIRR), Levelized Cost of Energy (LCOE), and Levelized Cost of Waste (LCOW). The analysis reveals an NPV of $4.99 million, an IRR exceeding 10%, and a payback period of 11.06 years, indicating economic viability. Additionally, the plant is projected to reduce annual CO2 emissions by 0.045 million tons, contributing to environmental sustainability. The findings demonstrate that waste-to-energy technology offers a viable solution for mitigating urban waste challenges while enhancing energy security, providing a sustainable pathway for Dhaka’s development and a model for similar urban context.
Evaluating The Impact of Innovative Technologies on The Management of Tour Services
Authors: Kharkhalis T. , Bohatyryova G. , Morhulets O. , Ovdiiuk O. , Tebenko V.
Published: January 2025

Purpose: The study aims to examine the effect of advanced technologies on tour Service Management regarding organising excursions and the overall quality of tourism services.
Design/Methodology/Approach: This research formed part of a larger study that embraced the case study research design that adopted quantitative and qualitative data. Data collection involved questionnaires completed by 137 respondents representing the tourism business sector in four European countries: Italy, France, Germany, and Ukraine. Moreover, the 23 industry experts were interviewed using an in-depth interview technique that primarily offered qualitative information. Correlation regression analysis was used to study technology usage patterns, and content analysis was used to get thematic trends and challenges.
Research Limitation: The sample size selected is adequate for preliminary findings, but the results may not be very generalisable for other categories of businesses in the tourism industry. Findings: The study's findings established that using Virtual Reality (VR) and Artificial Intelligence (AI) significantly improved the quality of excursions. The use of IoT was also revealed to enhance the control of tourist traffic, increase the level of security, and better the utilisation of resources.
Practical Implication: The study's practical significance lies in developing recommendations to enhance excursion management efficiency, such as integrating VR-based interactive tours.
Social Implication: VR, AI, and IoT can make valuable contributions to the tourist experience and increase customer satisfaction.
Originality/ Value: This work contributes by elaborating on how excursion management can be enhanced through the application of advanced technologies, including but not limited to VR, AI, and IoT, with a particular focus on the challenges that may arise in small and medium-sized enterprises operating within the tourism sector.
Optimising Coke Oven Gas Consumption in Heat Recovery Coke Production
Authors: Mahato N. , Agarwal H. , Kumbhalkar M. A. , Sarje S. H. , Sakhlecha M. , Mohod S. K. , Kardekar N. B. , Jain J.
Published: January 2025

Purpose: This research aims to optimise natural gas consumption in heat recovery coke production by systematically investigating operational parameters and process modifications. The objectives are quantifying and reducing specific gas consumption while maintaining product quality standards and developing optimal operating parameters for manual charging operations.
Design/Methodology/Approach: The experimental design for optimising natural gas consumption in coke production focuses on systematically evaluating and improving energy efficiency while maintaining product quality. The experimental runs are randomised to minimise systematic bias, with each condition replicated three times to ensure statistical validity. Statistical analysis employs Analysis of Variance (ANOVA) to determine significant factors.
Findings: Reducing heating gas leakage significantly improved temperature regulation within the Coke plant. Rectification measures enhance temperature distribution and optimise fuel consumption in the heating process. Saving coke oven gas energy as heating gas energy is also helpful for reducing the specific heat consumption value of coke-making plants in an integrated type of steel industry.
Research Limitation: This research is focused on recovery type coke making plants in integrated type steel industries
Practical Implication: These findings demonstrate that optimising coke oven gas consumption improves the efficiency of coke-making operations and generates substantial benefits across the entire integrated steel manufacturing process.
Social Implication: The social implications demonstrate that energy optimisation in coke-making plants contributes significantly to sustainable community development and social progress.
Originality/Value: Saving coke oven gas energy as heating gas is also helpful for reducing the specific heat consumption value of coke making plants in an integrated type steel industry.
Volcanic eruption tremor from particle impacts and turbulence using conduit flow models
Authors: Coppess Katherine , Lam Fredric , Dunham Eric
Published: January 2025

The intensity of explosive volcanic eruptions is correlated with the amplitude of eruption tremor, a ubiquitously observed seismic signal during eruptions. Here we expand upon a recently introduced theoretical model that attributes eruption tremor to particle impacts and dynamic pressure changes in the turbulent flow above fragmentation (Gestrich et al., 2020). We replace their point source model with Rayleigh wave Green's functions with full Green's functions and account for depth variation of input fields using conduit flow models. The latter self-consistently capture covariation of input fields like particle velocity, particle volume fraction, and density. Body wave contributions become significant above 2-3 Hz, bringing the power spectral density (PSD) closer to observations. Conditions at the vent are not representative of flow throughout the tremor source region and using these values overestimates tremor amplitude. Particle size and its depth distribution alter the PSD and where dominant source contributions arise within the conduit. Solutions with decreasing mass eruption rate, representing a waning eruption, reveal a shift in the dominant tremor contribution from turbulence to particle impacts. Our work demonstrates the ability to integrate conduit flow modeling with volcano seismology studies of eruption tremor, providing an opportunity to link observations to eruptive processes.
Comprehensive Bioinformatics Evaluation of CTNNB1 as a Diagnostic, Therapeutic and Prognostic Biomarker in Liver Hepatocellular Carcinoma
Authors: Raza Syed Hussain , Akram Muhammad
Published: January 2025

Liver Hepatocellular Cancer (LIHC) is a fatal disease, that keeps rigorous to therapeutic approach. This study explores the expression and promoter methylation of CTNNB1 and survival analysis, to extricate its role in LIHC progression, prognosis, and therapeutic approaches. Employing UALCAN, the study examined upregulation in CTNNB1 expression in LIHC as compared to normal samples explained its role in LIHC progression. Further analysis, stratified by patient’s age, gender, race, and pathological stages, revealed upregulation across all variables. Analysis of promoter methylation level of CTNNB1 in LIHC revealed hypomethylation, acknowledging upregulation of expression. Moreover, survival analysis of CTNNB1 using a KM plotter demonstrated its prognostic significance, as CTNNB1 overexpression results in the worst overall survival (OS) and vice versa. Validation via GEPIA2 affirmed elevated expression level of CTNNB1 in LIHC, further establishing its correlation with unfavorable survival outcomes. Furthermore, pathway enrichment analysis utilizing the STRING and DAVID tool identified association with genes implicated in essential signaling processes such as the Wnt signaling pathway revealing its role in LIHC progression. Subsequently, Genetic mutation analysis performed using cBioPortal demonstrated a 10% mutation of CTNNB1 in LIHC, indicating that alteration in the gene has a critical role in the development of LIHC. In conclusion, this comprehensive analysis highlights the significance of CTNNB1 upregulation in LIHC progression and its capability as a prognostic biomarker, offering valuable insight for developing targeted therapeutic strategies.
Evaluation of the Effect of Open Fistula Removal in the Surgical Treatment of Anal Fistula
Authors: Cao Jianlong
Published: January 2025

Objective: To analyze the treatment effect of open fistulotomy on patients with anal fistula. Methods: A total of 42 patients with anal fistula who visited the hospital from March 2021 to March 2024 were selected as samples and grouped using a random number table. The observation group received open fistulotomy, while the control group received conventional treatment. The differences in efficacy, surgical indicators, inflammatory factors, pain scores, and complications were compared. Results: The cure rate of patients with anal fistula in the observation group was higher than that in the control group, and the infection rate and recurrence rate were lower than those in the control group (P < 0.05). The surgical operation time, wound healing time, and hospital stay in the observation group were shorter than those in the control group (P < 0.05). There was no significant difference in intraoperative blood loss between the observation group and the control group (P > 0.05). The interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-10 (IL-10), and visual analog scale (VAS) scores in the observation group were lower than those in the control group (P < 0.05). The complication rate of patients with anal fistula in the observation group was lower than that in the control group (P < 0.05). Conclusion: Open fistulotomy for the treatment of patients with anal fistula can reduce inflammatory reactions, optimize surgical indicators, reduce pain, and is safe and efficient.
Identification of Immune-Related Feature Genes in Ovarian Cancer Using Bioinformatics and Analysis of Immune Cell Infiltration
Authors: Cao Huilu , Fan Yidong , Zhang Xiaolin , Wang Jing , Huang Zheng , Pan Jiongzuo , Fan Shujuan , Tan Qian
Published: January 2025

Objective: To identify immune-related feature genes in ovarian cancer through bioinformatics analysis and perform immune-related investigations, which hold significant value for the early diagnosis and prevention of ovarian cancer. Methods: Bioinformatics analysis was utilized to identify immune-related feature genes in ovarian cancer. The GSE18520 and GSE40595 datasets were downloaded from the Gene Expression Omnibus (GEO) database (https://www.ncbi.nlm.nih.gov/geo/) based on the gene expression comprehensive database, and the corresponding platform’s chip probe information was retrieved. GSE18520 served as the training set, and GSE40595 served as the validation set. A total of 2660 immune response genes (IRGs) were obtained from the ImmPort database (https://www.immport.org/home). Immune genes were screened and analyzed for feature genes using the “limma” package of R (4.2.1) software, and the results were visualized in a heat map. LASSO regression analysis and ssGSEA analysis were conducted to investigate the distribution of immune cell infiltration. Changes in regression coefficients of different genes in the model were also analyzed. Results: Five key genes—CLEC4M, DEFB1, LCN2, PTH2R, and LGALS2—were identified, and the correlation between these key genes and immune cells was analyzed. Conclusion: The findings indicate that CLEC4M, DEFB1, LCN2, PTH2R, and LGALS2 are significantly associated with various immune cell types, suggesting that these genes may regulate immune cell behavior and influence disease progression. This bioinformatics study provides a foundation for potential therapeutic targets in ovarian cancer; however, further clinical and experimental studies are required to validate the findings.
Observations On the Use of Personalized Composite Flaps in Postoperative Repair of Eyelid Tumour Excision
Authors: Li Kunling , Li Dan
Published: January 2025

Objective: To analyze the application effect of personalized composite flap technology in the postoperative repair of eyelid tumour excision. Methods: To retrospectively analyze the clinical data of 76 patients who underwent postoperative repair of eyelid tumour excision in the outpatient clinic of the Affiliated Hospital of Hebei University during May 2022–April 2024, and group them according to the method of repair. 38 patients who underwent local flap transfer repair were included in the control group, and the other 38 patients who underwent personalized composite flap repair were included in the observation group. Results: Eyelid defect repair in the patients of the observation group was significantly higher than that of the control group (78.95%) in the total effective rate of defect repair (97.37%), (P < 0.05); before repair, the difference between the two groups of patients in terms of eyelid fissure length difference and eyelid fissure height difference was insignificant (P > 0.05); after repair, the difference in the length of the eyelid fissure and eyelid fissure height difference of the patients of the two groups was significantly reduced, and the observation group was lower than that of the control group (P < 0.05); before repair, there was no statistically significant difference between the aesthetic function scores of the two groups (P > 0.05); after repair, the aesthetic function scores of the patients in the observation group were significantly higher than those of the control group, and the difference was statistically significant (P < 0.05); after the operation, the total incidence of complications such as ptosis, eyelid margin incision marks and suture disintegration in the observation group was significantly lower than those in the control group (26.32%), (P < 0.05). Conclusion: The application of personalized composite flap technique for postoperative repair of eyelid tumour excision is effective, which not only helps to reduce the difference in lid height and length and improve the appearance of the patients, but also greatly reduces the risk of complications such as ptosis, lid margin incision marks and suture disintegration, and is recommended to be widely used in the clinic.
IGF2BP1 in Mesenchymal GBM Immune Signalling Regulation via c-Myc
Authors: Wang Chen
Published: January 2025

Glioblastoma multiforme (GBM) is a highly aggressive and lethal brain tumor, with poor patient prognosis and median overall survival of only 10 months despite the current Stupp protocol treatment, due to its high aggressiveness and recurrence rate. This study investigated the role of the IGF2BP1 gene in mesenchymal glioblastoma multiforme (GBM), revealing that IGF2BP1 is upregulated in tumor tissues compared to adjacent normal tissues and positively correlates with MYC gene expression and poor patient prognosis. Immune infiltration analysis showed that IGF2BP1 is associated with specific immune cell populations, and GSVA analysis confirmed its positive correlation with the immune functions of most B cells and macrophages. The mechanism of IGF2BP1 regulating c-Myc expression in mesenchymal GBM and its subsequent impact on immune-related signalling pathways, thereby affecting the immune microenvironment of tumors and patient prognosis, provides new targets and ideas for future immunotherapy of mesenchymal GBM.
Efficacy of Melatonin in Neonatal Sepsis with Respiratory Distress: A Randomized Controlled Study
Authors: Hidayah Dwi , Nur Irfani Agita
Published: January 2025

Background: Neonatal sepsis is a significant condition worldwide, contributing to high morbidity and mortality, especially in developing countries such as Indonesia. Neonatal sepsis can rapidly progress to respiratory distress. Melatonin, an effective antioxidant and free radical scavenger, may be an adjuvant therapy. This study aimed to evaluate the efficacy of melatonin in neonatal sepsis with respiratory distress.
Subjects and Method: A double-blind randomized controlled study was conducted on 42 neonatal sepsis with respiratory distress diagnosed with clinical and laboratory criteria. The subjects were randomly allocated into treatment and control groups, receiving a single dose of oral melatonin 20 mg and a placebo, respectively. The dependent variables were improvement of suplementation in oxygenation and ventilator, outcome, and hospital length of stay. The independent variables was suplementation melatonin The oxygen supplementation and ventilation support were measured at baseline and 72 hours after therapy. We analyzed all data with SPSS 25 using independent t test and determined the significance level at p < 0.050.             
Results: Seven of the 21 subjects in the treatment group experienced decreased oxygen supplemen­tation and ventilation support, which was statistically significant (p = 0.009). While the outcome for both groups was the same proportion, it was statistically not significant (p = 1.000).
Conclusion: Melatonin administration significantly decreased oxygen supplementation and ventilation support.
Pengembangan Desain Antarmuka Sistem Informasi Keuangan Kas RT Berbasis Mobile dengan Metode Design Thinking
Authors: Ari Putra Wibowo Ari Putra Wibowo , Arief Soma Dharmawan  , Muhammad Faizal Kurniawan  , Devi Sugianti  , Risqiati
Published: January 2025

Penelitian ini bertujuan untuk mengembangkan desain antarmuka sistem informasi keuangan Kas RT berbasis mobile dengan menggunakan metode design thinking dimana objek pada penelitian ini adalah RT 06 Kelurahan Kuripan Yosoreko Kecamatan Pekalongan Selatan Kota Pekalongan. RT 06 merupakan salah satu RT yang sudah memanfaatkan teknologi informasi untuk pencatatan dan pelaporan uang Kas Warga. Untuk saat ini sistem informasi yang digunakan pada RT 06 Kelurahan Yosorejo adalah sistem informasi berbasis website dengan beberapa akun pengguna pengurus RT meliputi Ketua RT, Bendahara, Sekretaris dan warga. Metode design thingking digunakan karena dapat digunakan untuk mengeksplorasi berbagai macam kemungkinan yang menitikberatkan pengguna sebagai aktor utama. Adapun tahapan yang dilakukan pada penelitian ini antara lain  empathize, define, ideate, prototype dan testing. Hasil penelitian menunjukkan pengembangan desain antarmuka sistem informasi keuangan Kas RT berbasis mobile ini dapat diterima dan bisa digunakan sebagai solusi bagi pengguna. Sesuai dengan pengujian yang dilakukan dengan usability testing, dari beberapa responden yang telah dipilih dapat menyelesaikan semua skenario pengujian pada desain antaramuka baru
Analisis Sentimen Masyarakat Indonesia Terhadap Kebijakan Program Tapera Menggunakan Brand24
Authors: Rohmania Dyah Ratna , Rohmad Abidin
Published: January 2025

Penelitian ini menganalisis sentimen masyarakat Indonesia terhadap kebijakan program Tabungan Perumahan Rakyat (Tapera) dengan menggunakan metode netnografi dan alat analisis Brand24. Metode penelitian yang digunakan adalah deskriptif kualitatif dengan pendekatan netnografi, yang mengkaji data dari berbagai platform media sosial, blog, video, forum, berita, dan website. Data dikumpulkan dari periode 14 Mei 2024 hingga 13 Juni 2024, dan dianalisis untuk mengidentifikasi sentimen positif, negatif, dan netral terhadap kebijakan Tapera. Hasil penelitian menunjukkan dominasi media sosial sebagai sumber utama opini publik, diikuti oleh TikTok dan video. Analisis ini memberikan gambaran yang komprehensif mengenai tanggapan masyarakat terhadap kebijakan Tapera, yang dapat menjadi dasar dalam pengambilan keputusan dan perumusan strategi kebijakan yang lebih efektif.
Artificial Intelligence dan Filsafat Ilmu: Bagaimana Filsafat Memandang Kecerdasan Buatan Sebagai Ilmu Pengetahuan
Authors: Arditya Prayogi  , Riki Nasrullah
Published: January 2025

Kecerdasan buatan atau artificial intelligence ialah suatu konsep penanaman pengetahuan pada mesin untuk dapat melakukan kegiatan atau aktifitas seperti manusia lakukan, yang dengan ditanamkannya kecerdasan buatan tersebut, memiliki tujuan untuk membantu manusia dalam menyelesaikan segala hal yang tidak dapat dilakukan oleh manusia. Pemahaman ini kemudian memunculkan pertanyaan apakah kecerdasan buatan kemudian menjadi bagian dari ilmu pengetahuan itu sendiri. Artikel ini disusun dengan pendekatan kualitatif berbasis studi pustaka dengan dibantu metode analisis isi. Dari hasil telaah didapatkan gambaran bahwa kecerdasan buatan masuk ke dalam pemahaman intermediary domain yang secara prinsip berjalan serta menjadi bagian dari ilmu pengetahuan baik teoretis sekaligus empiris. Hal ini menjadikan kecerdasan buatan tidak hanya memiliki implikasi filosofis terhadap status epistemologis, namun juga secara aksiologis dan juga ontologis yang menjadi bagian dari filsafat ilmu. Tidak hanya itu, kecerdasan buatan juga meniscayakan adanya konsekuensi praktis yang dengannya kecerdasan buatan menjadi bagian dari ilmu pengetahuan itu sendiri.
Museum Guide Application Menggunakan Augmented Reality Berbasis Android
Authors: Eko Agustinus Eko Setiawan , Dinda Rahmadanty  , Ratnasari  , Dwi Yana Ayu Andini
Published: January 2025

Penelitian ini mengembangkan aplikasi pemandu museum menggunakan teknologi Augmented Reality (AR) berbasis Android, dengan fokus pada Museum Ketransmigrasian Lampung. Tujuan dari penelitian ini adalah untuk meningkatkan pengalaman edukatif pengunjung dan menarik lebih banyak wisatawan dengan menyajikan informasi koleksi museum secara interaktif dan visual. Metode penelitian yang digunakan adalah pendekatan kualitatif dan kuantitatif, serta model Multimedia Development Life Cycle (MDLC) yang terdiri dari tahap konsep, desain, pengumpulan bahan, perakitan, pengujian, dan distribusi. Hasil penelitian menunjukkan bahwa aplikasi ini berhasil meningkatkan daya tarik dan keterlibatan pengunjung, serta memberikan akses informasi yang lebih mudah mengenai koleksi museum. Pengujian menunjukkan bahwa marker dapat terdeteksi dengan baik dalam jarak 8 hingga 50 cm, serta tetap dapat dikenali meskipun terhalang hingga 50%. Diharapkan aplikasi ini dapat menjadi solusi praktis dalam penyampaian informasi di museum, serta meningkatkan minat masyarakat terhadap warisan budaya
Pengujian Sistem Informasi Pendaftaran Job Fair di Institut Widya Pratama dengan teknik Equivalence Partitioning
Authors: Maulana Mohammad Reza , Muhammad Faizal Kurniawan  , Wahyu Setianto
Published: January 2025

Institut Widya Pratama (IWIMA) terus berupaya dalam mencetak lulusan yang berkualitas. Untuk memberikan kesempatan yang lebih baik untuk lulusan IWIMA rutin mengadakan kegiatan job fair untuk mempertemukan calon pencari kerja dan perusahaan. Salah satu masalah yang muncul dalam pelaksanaan kegiatan ini adalah proses pendaftaran dan pendataan calon pencari kerja. Dari mengatasi permasalahan tersebut, IWIMA mengembangkan sistem informasi pendaftaran job fair bagi calon pelamar kerja. Untuk memastikan sistem informasi dapat digunakan dengan baik dan lancar diperlukan proses pengujian sistem. Salah satu teknik yang dapat digunakan untuk menguji sistem adalah equivalence partitioning. Teknik ini akan memastikan bahwa antara input dan output telah sesuai dengan perancangan aplikasi dengan menerapkan skenario-skenario pengujian. Tahapan penelitian ini diantaranya adalah pembuatan desain pengujian, proses pengujian dan pencatatannya serta evaluasi hasil pengujian. Tahap awal penelitian yaitu pembuatan desain dilakukan dengan menghasilkan usecase pengujian, paramater uji, partisi uji, data uji dan test case pengujian. Selanjutnya, dari hasil pengujian sistem yang telah dilakukan sebanyak tujuh test case, didapatkan hasil bahwa sistem informasi dapat berjalan dengan baik sesuai yang diharapkan. Meskipun demikian, dari hasil evaluasi yang sudah dianalisis, sistem informasi direkomendasikan untuk ditingkatkan kualitasnya. Saran tersebut dapat digunakan sebagai acuan pengembangan selanjutnya.
Gender specificity of the space of war in the novel “Dotsia” by Tamara Horikha Zernia
Authors: Tiutiun Viktoriia
Published: January 2025

The relevance of this study is due to the need for a detailed research of women's war novels in modern literature that artistically comprehend the events of the Russia-Ukraine war and represent them from the perspective of women's experience. The emphasis on women's literature is important, as studies on war fiction written by men remain largely represented in terms of numbers. The study of the chronotope in military literature is relevant considering its participation in shaping the image of the military world view. Of particular interest to us is the topic of the correlation between space and gender in women's war fiction, which has been addressed by foreign researchers but is not sufficiently developed in Ukrainian literary studies. The purpose of the article is to research the specifics of the representation of peaceful and military artistic space, its gender semantics in a female war novel. The study is carried out in the theoretical coordinates of feminist studies with the use of chronotopic and hermeneutic analysis. The object of the study is the novel “Dotsia” (“Daughter”) by Tamara Horikha Zernia. The subject of the study is the gender specificity of the chronotope.
As a result of the study, the main spatial modes of war in the novel were analysed. Outlined was the chronotope of the occupation, which is characterised by the suspension of time, the devastation of space and the heterogeneity of the war's impact on individual locus. It is revealed that the front in the novel is a “hyperspace” without a centre and clear boundaries. It is proved that the writer refuses to form the opposition of front and home, and the crimes of war take place in traditionally feminine locus, which destroys the myth of women’s space as “safe”. The analysis of the image of Dotsia and other characters in the novel proves that women become involved participants in the war.
The scientific novelty lies in the study of space in Tamara Horikha Zernia’s novel from the perspective of feminist studies, which made it possible to trace the writer's vision of peaceful and wartime space, its feminine and masculine semantic, and to outline the specifics of the occupation chronotope.
Ways of nominating the enemy in media texts
Ukrainian and Polish documentary films and Ukrainian feature films and mass media
Authors: Rosinska Olena
Published: January 2025

The article presents the analysis of language units to denote an enemy used in media content of different genres: official media reports, documentaries and feature films. The relevance of the study is determined by the urgent need to study the peculiarities of linguistic film discourses in the media in general and cinema as a special type of media content. The subject of the research is the linguistic forms of naming the enemy in Ukrainian documentary and feature films during the period of the full-scale invasion and the use of similar forms in media texts to determine the peculiarities of the correlation between different media genres. The researcher set the goal of describing the linguistic forms used to name the enemy and to trace their correlation in various media genres. The following methods were used to achieve this goal: content analysis, comparative analysis, semantic analysis, context analysis.

The results of the study prove that the words with the attribute of hate speech that contain an intention of humiliation, disrespect, etc., are a special linguistic strategy which becomes leading for media during the period of the armed confrontation. Similarity in narratives and nominations proves the formation of a common speech discourse for the media content different in nature. Among the most widely-spread denominations one can determine: “rusnia”, “katsap / katsapnia”, “rusсists”, “moskals”, “orks”, “nechyst”, the use of such notions as “Russian world”, “liberators” marked by propaganda and used ironically and derogatorily also draw attention.

Such denominations are a manifestation of the language of enmity, which is usually perceived as an undesirable manifestation of mental intolerance, however, in times of war, the formation of a whole layer of such denominations appears as a manifestation of resistance, ideological opposition to the enemy, a psychological mechanism of its dehumanization against the background of a heightened perception of one’s identity in the face of a threat.
OVERCOMING SPEECH BARRIERS AT UNIVERSITY FOREIGN LANGUAGE CLASSES
Authors: Durdas Alla , Furmanchuk Nataliia , Bondar Anna , Samar Olena
Published: January 2025

This article focuses on the importance of developing speaking skills at foreign language classes at university, as the ability to communicate in English is one of the essential requirements for success in various careers both nationally and internationally. However, while speaking a foreign language university students face challenges like hesitation, limited vocabulary, anxiety and lack of real-world practice. Traditional methods often struggle to address these issues due to large classes, limited interaction and time constraints. Teaching speaking is particularly demanding, requiring focus on pronunciation, grammar and fluency, along with overcoming shyness, low confidence and fear of judgment. To overcome these barriers, teachers should use innovative methods and technologies. Techniques like communicative language teaching, task-based learning, immersion, and digital tools help students build confidence and fluency. Activities like role-playing and digital storytelling make language use more natural and reduce anxiety. The article highlights the importance of adapting teaching methods to students’ needs, focusing on real-world application of a foreign language like professional communication. Practical strategies include regular practice, engaging with native content, cultural exploration and learning from mistakes. By creating supportive and interactive environments, teachers can help students to become confident speakers, preparing them for successful work and realization in a globalized world.
FEATURES OF ADULT EDUCATION CENTERS IN ENGLAND
Authors: Fedchyshyna Anastasiia
Published: January 2025

The article reveals the peculiarities of adult education centers in one of the countries of the United Kingdom of Great Britain and Northern Ireland – England, which are based at universities, colleges, charitable organizations, etc. The peculiarities of adult education centers in England were determined and analyzed according to certain structural characteristics: axiological orientation, organizational, methodical and information-content provision of the adult education process. It is noted that the main goals of the institutions that provide non-formal adult education in England are the creation of opportunities for obtaining knowledge, skills, qualifications and retraining; promotion of employment and psychological well-being of the adult population; overcoming the main barriers in the employment process; development of digital skills, provision of an inclusive environment and others. It is noted that education providers in England offer a wide selection of forms of adult education, which contribute to the development of professional and personal skills, career growth; provide continuous professional development, acquisition of practical experience and flexible training. It was determined that among the priority areas of adult education in England there are civic education, futures of education, second higher education, technical and vocational education, liberal adult education, professional education, education policy and others.
Pseudo-static analysis of tunnel face stability using the Mohr-Coulomb strength criterion
Authors: Saada Zied , Garnier Denis , Maghous Samir
Published: January 2025

The paper addresses the stability analysis of a circular tunnel face driven by a pressurized
shield by means of the limit analysis kinematic approach implemented in the context of
the Mohr-Coulomb strength condition. Emphasis is given to the assessment of the effects
of seismic loading on the value of face support pressure that is required to prevent failure.
The approach relies upon the pseudo-static method to model the destabilizing effects
induced by the inertial forces associated with the passage of seismic waves in the ground.
Rigorous limit analysis solutions for the limit face supporting pressure are derived from
the analytical implementation of 3D and 2D failure mechanisms specifically devised for
dealing with such a stability analysis problem. Indeed, original analytical expressions are
provided and allow the evaluation of the pressure stabilizing the tunnel face. The accuracy
of the approach predictions is assessed by comparison with available experimental and
analytical results as well as with 2D finite element solutions. The influence of some relevant
problem parameters in the context of tunnel face stability analysis is finally investigated,
thus providing some preliminary guidelines for practical use in tunnel engineering.
Covid Diary Birgit Birnbacher
Authors: Birnbacher Birgit
Published: January 2025

Covid Diary Birgit Birnbacher
Covid Diary Christian Mähr
Authors: Mähr Christian
Published: January 2025

Covid Diary Christian Mähr
Covic Diary Thomas Stangl
Authors: Stangl Thomas
Published: January 2025

Covic Diary Thomas Stangl
List of translators
Authors: Platje Johannes (Joost)
Published: January 2025

List of translators
Covid Diary Michael Stavaric
Authors: Stavaric Michael
Published: January 2025

Covid Diary Michael Stavaric
The impact of China’s foreign trade on their Actual-Open Emissions of CO2 in the years 2000–2020 in the context of EU energy policy
Authors: FORTUŃSKI Bartosz
Published: January 2025

Aim:  This article aims to analyze the impact of China’s trade with 78 major trading partners on Actual-Open Emission of CO2 (EAO) from 2000 to 2020 in light of the European Union's (EU) goal to reduce CO2 emissions by 20% by 2020 compared to 1990 levels.
Research Methods: The research is based on the Actual-Open Emission of CO2 model and employs the circular flow model to assess the influence of China's foreign trade on CO2 emissions during the years 2000–2020.
Findings: The study revealed that China’s foreign trade significantly influenced its CO2 emissions in all years analyzed, with positive contributions to EAO due to a trade surplus (exports exceeding imports). As the world’s largest exporter and the second-largest importer, China’s trade activity resulted in substantial CO2 emissions. Four key indicators were identified as influencing the difference between Official-Close Emission of CO2 (EOC) and EAO: China’s GDP, the percentage of exported GDP, the percentage of imported GDP, and EOC levels. These findings highlight the significant role of trade in China’s CO2 emissions, which is critical in the context of EU initiatives like “Fit for 55.”
JEL: F18, Q54, Q56,
KALAPANI, LIPULEKH, LIMPIYADHURA DISPUTE AND CHALLENGES IN INDIA-NEPAL RELATIONS
Authors: Kumar Pardeep , Kumar Navin
Published: January 2025

Geographical location, socio-cultural environment, economic interdependence, have had a great influence in determining the relations between India and Nepal. In fact, there are very few countries in the world that are so closely intertwined with each other as India and Nepal. A clear depiction of person to person relations is seen in India-Nepal relations. The open border of both countries has further enriched this closeness. India is an important and large ally of Nepal. India has the most trade partners with Nepal and also has the highest foreign investment etc. However, sometimes border disputes between the two become serious issues. The recent border dispute is related to the Kalapani region, which has affected relations between the two countries because both present historical evidence in their favor. The current border dispute has seriously impacted both the countries, which were considered to have an open border and served as a model for the world. China is increasing its role in the India-Nepal border dispute. Therefore, in this research paper, we will describe how India and Nepal can resolve this border dispute, considering their historical relations. India and Nepal can resolve their border dispute in a formal and friendly manner. What changes will the resolution of this border dispute bring to the relations between the two countries and what is the importance of this border dispute in India’s foreign policy?
CHINA’S INFLUENCE IN NEPAL: INDIA’S CONCERN
Authors: Kumar Pardeep , Kumar Navin
Published: January 2025

China’s strategic cooperation with India’s neighbours in South Asia, particularly Nepal, has been a matter of concern for us. Nepal’s geographical position has both advantages and disadvantages. It is like a sandwich between two giants: China to the north and India to the south, and both of these forces are opposed to each other. Nepal keeps playing the game by bowing to the pressure of both. Observing them interact, Nepal is also increasing its capabilities. However, in recent years, China has adopted a strong diplomatic relationship with other South Asian countries besides India by providing economic and technical assistance. These states are playing the ‘China card’ by receiving such assistance from India. China wants to eliminate India’s traditional influence over these countries, but India has always believed that if its security is taken care of, then it has some tension with Nepal for its own security reasons. This is also because the relations between China and Nepal have become closer in recent years. Strategic relations between India and Nepal are in place, but due to the history and geography of both, Nepal’s dependence on India has started decreasing. Now it has become a permanent fact that China is putting pressure not only on Nepal but also on other countries in South Asia. These developments are harmful for India: not only are its close agreements with Nepal being affected, but India’s security is also being comprised due to the entry of outsiders in South Asia. Therefore, in this research paper, we will describe how Nepal has affected India’s foreign policy due to the influence of China and how the deepening relations between Nepal and China have distanced Nepal from India. What challenges can India face from these relations and is it also posing a threat to India’s security?
AI in enhancing cultural sensitivity
Authors: Mariyono Dwi , Abror Mufidul
Published: January 2025

This study investigates the role of Artificial Intelligence (AI) in promoting multicultural sensitivity and inclusivity in education. Using the PRISMA framework, 71 primary articles were analyzed from ERIC, ProQuest, Scopus, and Web of Science. Findings indicate that AI-based instructional media outperform conventional methods in improving cultural representation and reducing implicit biases. However, challenges such as algorithmic bias and unequal access persist, underscoring the need for ethical frameworks and culturally responsive pedagogies. This research highlights AI's potential to foster adaptive learning environments, enhance engagement, and address educational inequalities. Recommendations emphasize the importance of ethical AI implementation to support equitable and inclusive practices in multicultural education.
Bioactivity of Nelumbo nucifera extract on sperm recovery due to 2-methoxyethanol exposure: In vivo and in silico study
Authors: Syaputra Angella Ananda , Setiyowati Putri Ayu Ika , Musyarofah Badriatul , Kasanah Yunita Ainul , Rahmawati Amelia Kartika Reza , Qotrunnada Helga Syasya
Published: January 2025

One of the causes of male infertility is influenced by the compound 2-Methoxyethanol (2-ME) that can increase Reactive Oxygen Species (ROS), which affect sperm quality. This study aims to analyze the effects of various doses of Nelumbo nucifera extract on sperm quality in mice. Methods: Male ddy mice were divided into six equal groups. The negative control group was given aquades for 28 days, the positive control group was injected with 0.05 ml of 2-ME for 7 days, compare control group was injected with 0,05 ml 2-ME and clomiphene citrate 50 mg for 21 days. The treatment groups were injected with 0.05 ml of 2-ME for 7 days followed by injection different doses of N. nucifera extract, namely 50 mg/kg body weight (BW), 150 mg/kg BW, and 450 mg/kg BW for 21 days. At the end of the experiment, the mice were sacrificed, and sperm suspensions were collected from the epididymis to measure morphology, concentration, and motility. In silico testing was performed by preparing ligands and the GSK3b protein receptor using PyMOL, and then tested to determine the binding energy using PyRx. Results: The administration of N. Nucifera extract can significantly improve sperm morphology, concentration, and motility (p<0.05). The dose of 450 mg/kg BW has a pronounced protective effect. Quercetin is the compound of N. nucifera extract with the highest inhibition of non-receptor protein kinase and the most significant antioxidant effect. N. nucifera extract can improve the decline in sperm quality caused by exposure to 2-Methoxyethanol.
Effect of different speed and time of centrifugations on decontamination of Leptospira spp. cultures from rat’s kidney
Authors: Budi Prasetyo  , Arif Mulyanto  , Kusnanto Mukti Wibowo  , Kurniawan  , Farida Dwi Handayani
Published: January 2025

The centrifugal force in the centrifuge is able to change the surface properties of bacterial cells and the inner structure, including DNA, so that it can damage bacterial cells. The pathogenic bacterium Leptospira spp is a zoonosis that lives in the kidneys of rats as a natural reservoir, but breeding it is still a challenge because it can be contaminated with other bacteria. Decontamination methods are needed to obtain clean and pure Leptospira spp cultures for further examination and epidemiology. This study aims to obtain an appropriate decontamination method for the sustainability of Leptospira spp cultures in the laboratory using a combination of centrifugation speeds. Leptospira spp cultures were obtained from leptospirosis endemic areas in Central Java Province, Demak Regency, Gebang Village and Tridonorejo as many as 13 Leptospira spp cultures contaminated with cocci, coma, and filaments. Cultures were observed at 20x magnification under a dark field microscope at 8 weeks old. Contaminated cultures were centrifuged at 3000, 6000, and 8000 rpm for 5 and 10 minutes, then recultured into new media. The media used in this study were EMJH + STAFF and V5FU media. The results showed that rat kidney cultures showed 7 and 6 positives from the Gebang and Tridonorejo areas. Data on the results of bacterial decontamination obtained at a speed of 3000 rpm for 5 minutes has a greater percentage than the speed of 6000 and 8000 rpm with a result of 30.8%. This is in the process of purifying Leptospira spp using centrifugation proven to remove contaminant bacteria such as cocci, coma, and filaments. This is because centrifugation speed is able to change the nature of the surface structure and interior of bacterial cells, including DNA, so that it can damage bacterial cells.
Performance Analysis for RC6 and PRESENT Encryption Algorithms in Cloud Environment
Authors: S. Salman Doaa , H. Ali Huda
Published: January 2025

Organizations and individuals increasingly rely on cloud services for data storage and transmission, and the need for robust and efficient encryption algorithms is more critical than ever. This paper rigorously examines the performance and NIST compliance of two lightweight encryption algorithms, RC6 and PRESENT, within cloud computing contexts. The paper assesses the algorithms' performance metrics, such as encryption time, decryption time, space-time, memory used, CPU consumption, avalanche effect, entropy, and energy consumption, in addition to their security features. Also, utilizing fifteen NIST SP 800-22 cryptographic tests to ensure secure and efficient practices, including recent security analyses to assess the two algorithms' behavior, both algorithms present a distinct array of compromises between effectiveness and protection.
The results function as a strong regulator for the decision-making process in cloud security, offering advantages to both professionals in the field and experts in cryptography, it shows RC6 outperforms PRESENT in encryption (5.334s vs. 6.937s), decryption (6.035s vs. 6.191s), and space-time efficiency (1189 bytes/s vs. 41 bytes/s). While PRESENT uses less memory after encryption (41.27 MB vs. 67.63 MB), RC6 has slightly lower CPU consumption (4.50% vs. 4.90% for encryption) and higher energy efficiency (0.901J vs. 0.956J). Deep analysis is implemented to balance security and efficiency, and after implementing the two algorithms to encrypt the same file the result of the analysis was, that RC6 stands out as a particularly strong contender. It offers robust security features and is more efficient in terms of computational time, resource utilization, and energy consumption. PRESENT, while secure, tends to consume more resources and takes longer for encryption and decryption. However, its simpler design might offer some advantages in certain scenarios, though this comes with trade-offs in performance and resource efficiency.