bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparação de técnicas de prototipagem tradicional manual e sua importância para o design
Authors: Pereira Douglas , Lanutti Jamille , Paschoarelli Luis Carlos , Pinheiro Olympio
Published: March 2018

O Design é uma atividade muito ampla, que consiste em criar produtos, objetos que em seguida serão fabricados e comercializados. Dentro desse processo de criação existe uma etapa imprescindível que é a utilização de modelos e protótipos, que podem ser confeccionados nos mais diferentes tipos de técnicas e materiais. Assim esse trabalho tem como objetivo comparar diversas técnicas de prototipagem tradicional executadas manualmente, utilizando e classificando variadas técnicas e materiais, levando em consideração critérios como Custo, Tempo de execução e Nível de dificuldade, elegendo para isso um produto (embalagem) que servirá de exemplo a fim de gerar comparações entre os modelos desenvolvidos.
A abordagem de design e materiais no âmbito do PPGDesign/Univille
Authors: Aguiar Victor , Santos Adriane , Sobral João , Everli Marli
Published: March 2018

Este relato apresenta a estruturação dos conteúdos técnico-científicos associados à disciplina de Materiais e Processos de Fabricação no âmbito do Programa de Pós-Graduação em Design da Universidade da Região de Joinville (PPGDesign/Univille). Em virtude da natureza profissional do mestrado, a translação de conhecimentos de base científica e tecnológica em capacitação técnica, considerando a sua aplicabilidade, foi o norte da disciplina.
A borracha sintética de chinelos descartados no design de produtos
Authors: Forcato Marcelo , Dias Joner , Dalberto Anelise , Ortiz Guilherme
Published: March 2018

Este artigo apresenta resultados obtidos por projeto de pesquisa que objetivou investigar e desenvolver material proveniente de resíduos sólidos de borracha sintética de chinelos descartados além de sugerir aplicações em design de produto. Com a utilização deste resíduo em estado de pó, foram realizados testes com aglutinantes artificiais e vegetais que formaram alternativas de materiais que posteriormente foram submetidos a testes químicos e físicos. Como resultados, obtiveram-se três materiais experimentais que utilizam aglutinantes de baixo impacto ambiental. Neste artigo será apresentado um dos materiais obtidos bem como sugestão de aplicação no design de superfície.
Materiais e processos na indústria náutica
Authors: Schmidt Marco Aurélio , Everling Marli , Santos Adriane Shibata
Published: March 2018

A definição de materiais e processos no desenvolvimento de um produto pode direcionar o processo projetual a ser aplicado e, em alguns casos, promover a inovação. Considerando a indústria náutica brasileira, seu contexto e necessidades, este artigo apresenta o resultado de um projeto de mestrado que objetivou criar uma proposta de produto para ganho de eficiência operacional, aumento da produtividade e redução do desperdício. Como resultado foi elaborado um sistema de plataforma modular que comporta três modelos de embarcações e seus diferentes acessórios. Considerando requisitos do ecodesign, o resultado também apresentou o potencial de ganhos e redução de custos na cadeia produtiva, considerando a empresa, as pessoas e o meio ambiente.
Arte e técnica da marchetaria aplicada no design de mobiliário contemporâneo
Authors: Vieria Ardalla , Nejeliski Danieli , Rigo Fernanda
Published: March 2018

A produção de estampas, texturas e relevos por meio do design de superfície tem possibilitado a criação de projetos criativos e ousados, para diferentes segmentos da produção industrial, entre eles o setor moveleiro. A marchetaria é uma técnica de ornamentação de superfícies planas através da criação de desenhos com a aplicação de diferentes materiais, especialmente lâminas de madeira. O presente trabalho tem como objetivo a criação de um padrão de marchetaria a partir de um referencial conceitual e a posterior aplicação na superfície de um móvel. O conceito foi definido a partir da análise da constituição formal das Ruínas de São Miguel da Missões. O móvel desenvolvido foi uma mesa lateral, com a funcionalidade inspirada na estrutura das ruínas. A marchetaria foi feita a partir de módulos geométricos, nas cores vermelho, azul e madeira clara, sendo aplicada em uma das peças da mesa. Aliando uma técnica tradicional, de execução artesanal, com um referencial cultural, obteve-se como resultado um móvel de estilo contemporâneo. Por fim, foi produzido o protótipo do móvel.
Design, pedra, madeira e fibra natural
Authors: Pacheco Karla , Paixão-Barradas Susana , Pacheco Almir , Santos Patrícia Dos , Quirino Magnólia
Published: March 2018

O estudo apresenta uma experimentação com três matérias-primas naturais distintas: pedra, madeira e fibra no desenvolvimento de produtos voltados a ambientes comerciais com enfoque regional como hotéis e restaurantes. O projeto objetivou capacitar os discentes do Curso de Design da UFAM para a projetação de objetos decorativos através da tecnologia e da experiência profissional de quatro instituições de ensino e pesquisa do Brasil e da Europa. Foi utilizado o método qualitativo, com caráter descritivo, explicativo, exploratório e experimental, aplicando o levantamento bibliográfico, a observação in loco e análise de casos. Como resultados, foram gerados 13 (treze) protótipos com base nos estudos realizados.
Caracterização e definição de parâmetros de corte a laser em tubos de papelão
Authors: Piccoli Mariana , Pacheco Joyson , Brandi Leonardo
Published: March 2018

O objetivo deste trabalho foi identificar parâmetros técnicos de corte a laser em tubos de papelão, e caracterizar o material por meio de MEV e análise termogravimétrica ATG. Como resultados da caracterização, a temperatura de combustão indica que até os 210°C existe uma faixa de segurança na utilização dos tubos. A microscopia eletrônica de varredura mostrou as características morfológicas da superfície interna, externa, do miolo e da borda do tubo de papelão. Concluiu-se a viabilidade da aplicação da tecnologia de corte a laser no material, determinando-se a potência e velocidades adequadas para o corte mais eficiente em cada espessura. Após as pesquisas, demonstra-se que o tubo de papelão é um material passível de aplicação no design de produtos.
Real-time Parental Voice Recognition System For Persons Having Impaired Hearing
Authors: Yağanoğlu Mete , Köse Cemal
Published: March 2018

Persons having impaired hearing do not live a comfortable life because
they can’t hear sounds when they are asleep or alone at home. In this study, a
parental voice recognition system was proposed for those people. Persons having
impaired hearing are informed by vibration about which one of their parents is
speaking. By this means, the person having impaired hearing real timely
perceives who is calling or who is speaking to him. The wearable device that we
developed can real timely perceive parental voice very easily, and transmits it
to person having impaired hearing, while he/she is asleep or at home. A
wearable device has been developed for persons having impaired hearing to use
easily at home environment. Our device is placed on user’s back, and just a ring-sized
vibration motor is attached to the finger of person. Our device consists of
Raspberry Pi, usb sound card, microphone, power supply and vibration motor.
First of all, the sound is received by a microphone, and sampling is made.
According to the Nyquist Theorem, 44100 samples are made per second.
Normalization during preprocessing phase, Mel Frequency Cepstral Coefficients
(MFCC) during feature extraction stage, k nearest neighbor (knn) during the
classification phase were used. Statistical or Z-score normalization was used
in the pre-processing phase. By means of normalization of the data, it is
ensured that each parameter in the training input set contributes equally to
the prediction of the model. MFCC is one of the feature extraction methods that
are frequently used in voice recognition applications. MFCC represents the
short-time power spectrum of the audio signal, and models the manner of
perception of human ear. Knn is an educational learning algorithm, and its aim
is to classify the existing learning data when a new sampling arrives. The
sound data received via microphone were estimated through preprocessing,
feature extraction and classification stages, and the person having impaired
hearing was informed through real time vibrations about to whom this voice
belongs. This study was tested on 2 deaf, 3 normal hearing persons. The ears of
normal hearing persons were covered with a earphone that gives out loud noise.
Persons having impaired hearing estimated their mothers’ voice by 76%, and
fathers’ voice by 81% accuracy in real-time tests. The success rate decreases
due to the noise of environment especially while watching tv.  In the tests performed while these persons
are asleep, a person having impaired hearing perceives his/her mother’s voice by
78%, and   father’s voice by 83%
accuracy. In this study it was aimed for persons having impaired hearing to
perceive their parents’ voice and accordingly have a more prosperous standard
of living.
Chemical Characterization and Biological Activity Evaluation of Essential Oils of Achillea Sipikorensis, an Endemic Plant from Turkey
Authors: Eruygur Nuraniye , Çevik Özge , Ataş Mehmet , Tekin Mehmet
Published: March 2018

The Achillea
L. (Asteraceae) are known all over the world and used widely by local people as
folk herbal medicine.  The species are
reported to have anti-inflammatory, antioxidant, diuretic, antispasmodic vs.
activities and have been used for the treatment of various ailments in Turkish
traditional medicine. This work it the first study on chemical composition and
biological activity of essential oil obtained from endemic plant- A. sipikorensis Hausskn. Et. Bornm
evaluated for their antiradical, antimicrobial and cytotoxic activities. GC/MS
analyses showed that cis- chrysanthenol (14.5%), 1, 8-cineol (10.9%),
caryophyllene oxide (8.5%), borneol (8.2%), and camphor (6.1%) were the major
constituents in the essential oil from aerial part of the plant. The essential
oil demonstrated good antioxidant, antimicrobial and cytotoxic activities.
Orman Ekolojisinde Odunsu Vejetasyonun Sınıflandırmasına Yönelik Bir Çalışma (Isparta-Yenişarbademli Örneği)
Authors: Kurt Esra Özge , Negiz Mehmet Güvenç
Published: March 2018

Bu çalışma Yenişarbademli
ormanlık alanlarında odunsu vejetasyonunun sınıflandırılması amacıyla
gerçekleştirilmiştir. Vejetasyon sınıflandırması, biyolojik çeşitliliği korumak
ve devamını sağlamak adına önemli bilgiler vermektedir. Çalışmada arazi envanteri
ile 20x20 metre boyutlarında 103 örnekleme alanı alınmıştır. Her örnekleme
alanında odunsu bitki türleri ve yetişme ortamı özellikleri envantere
kaydedilmiştir. Çalışmada vejetasyon gruplarını ayırabilmek amacıyla kümeleme
analizi ve iki yönlü gösterge analizi gerçekleştirilmiştir. Kümeleme analizi ve
iki yönlü gösterge analizi gerçekleştirilirken bitki türlerine ait var- yok
değerleri kullanılmıştır. Kümeleme analizi ile gösterge tür belirlenemediği
için ayrıca nitelikler arası ilişki analizi uygulanmıştır ve toplamda 6 farklı
analiz uygulanmıştır. Yapılan analizler sonucunda hangi grupların kullanacağına
karar vermek amacıyla kümeleme analizi ve iki yönlü gösterge analizi
sonuçlarına çoklu permütasyon testi (MRPP) analizi uygulanmıştır. MRPP
analizinin sonucuna göre iki yönlü gösterge analizinin beş göstergeli ikili
grup ayrımı üzerinden yorumların yapılmasının daha uygun olduğuna karar
verilmiştir.  Vejetasyon
sınıflandırmasına yönelik gerçekleştirilen birçok çalışmada da iki yönlü
gösterge analizinin etkili ve güncel bir yöntem olarak seçilmiş olması da elde
ettiğimiz bu sonucu doğrulamaktadır. İki yönlü gösterge analizinin 5 indikatör
ikili grup ayrımı sonucunda THYSAM, CIRARV, BERVUL, JUNOXY, EUPSPP türleri
ayrıcı türler olarak tespit edilmiş, ayrıca ikili ayrımın ilk grubunu 51,
ikinci grubunu 52 örnekleme alanı temsil etmiştir. Ayrıcı türler incelendiğinde
çalışma alanın yüksek kesimlerinde yer alan türler olduğu görülmektedir. Burada
ilk grupta bu türler pozitif göstergeler iken, ikinci grupta negatif gösterge
niteliğindedir. Dolayısıyla çalışmanın sonucu olarak; grup ayrımlarının
oluşmasında ve gösterge türlerinin tespit edilmesinde yükseltinin en önemli
değişken olduğunu söylemek mümkündür.
Numerical Analyses of the Effects of Fuel Load Variation on Combustion Performance of a Pellet Fuelled Boiler
Authors: Sungur Bilal , Topaloglu Bahattin
Published: March 2018

Domestic
and industrial energy requirements since the beginning of industrial revolution
have been largely met by fossil fuels. This leads to a continuous increase in
the Earth's atmosphere of carbon dioxide and other harmful components. Also
fossil energy resources decreasing day by day and scientists have turned to new
research. In this context alternative energy sources have an important role to
reduce dependence on fossil fuels. One of the alternative energy sources is
biomass and pellet fuel is one of them. In this study, combustion
characteristics of pellet fuel in a model smoke tube boiler at different
loading conditions were investigated numerically. As a Computational Fluid
Dynamic (CFD) program FLUENT package program was used. Calculations were
performed at two dimensional conditions. According to various loading
conditions, temperature and stream function contours, velocity vectors, exhaust
gas temperatures and efficiencies were investigated and results were discussed.
An Assessment of Shallow Groundwater Wells In An Agricultural And Coastal Area In Göksu Delta, Turkey
Authors: GÜNER Esra Deniz , TEKİN Senem , SEÇKİN Galip
Published: March 2018

The Göksu
Delta of Turkey is an alluvial delta with intense agricultural activity and has
great ecological and economic significance. Water samples were collected
monthly from 24 wells in the study area, and 13 water quality parameters were
examined. The objective of the study was also to determination the water
quality in wells of the Göksu Delta and assess levels of salinisation in the
region. Piper diagrams and the Geographic Information Systems (GIS) was used to
generate ionic ratios to evaluate water quality in the study area in an
efficient  manner. Overall, the
groundwater examined has medium levels of salinity and low sodium content.  The ncrease in groundwater salinity and
amounts of Na+ and Cl- are indicators of saltwater
intrusion. Rock dissolution and ion exchange were also found to play an active
role in the region. All of these factors affect the sustainability of the
freshwater aquifers and lower their quality for wildlife species.
Sapwood Area Related to Tree Size, Tree Age, and Leaf Area Index in Cedrus libani
Authors: Güney Aylin
Published: March 2018

Sapwood
includes the water conducting part of the stem which transports water and
minerals from roots to leaves. Studies using sap flow gauges have to determine
the area of the sapwood in order to scale measured sap flow densities to the
tree or stand level. The aim of this study was to investigate the relationship
between sapwood area at breast height and other tree parameters which are easy
to measure of the montane Mediterranean conifer Cedrus libani, including a total number of 92 study trees of
different size and age. The study was conducted at four different stands
situated between 1000 and 2000 m altitude in the Elmalı Cedar Research Forest
of Antalya, SW-Turkey. Sapwood area of the sample trees was determined by
extracting two tree cores from opposite directions of the stem using an
increment borer and by visually assessing the wet part of the core. Parameters
measured besides sapwood area were diameter at breast height, stem radius
without bark, sapwood depth, tree basal area, tree height, tree age, and projected
crown area. Furthermore, at each stand, leaf area index (LAI) was determined
using hemispherical photographs of the forest canopy. The most significant
relationship was found between stem radius without bark and sapwood area (R2:
0.94) followed by tree basal area and sapwood area (R2: 0.90).
Although it was the second best predictor, tree basal area should be used to
estimate sapwood area when estimating stand transpiration since it can be
measured faster and without giving damage to the tree. Mean sapwood area and mean
site-specific LAI showed a significant positive correlation. The findings of
this study can be used in ecophysiological studies when transpiration rates of C. libani are measured using sap flow
gauges.
Infrared and NMR Spectral Analyses and Computational Studies of 2-amino-3-methylbenzoic acid
Authors: Yıldırım Muhammet Hakkı
Published: March 2018

Detailed infrared spectrum in gas phase, NMR spectra analyses and theoretical studies of 2-amino-3-methylbenzoic acid were performed with DFT/B3LYP/6-311G+(2d,p) level of method in Gaussian 09W. Ground state molecular geometries of monomeric and dimeric structures were calculated in vacuum and compared to the experimental XRD results. Potential energy surface graphics of the proton transfer and torsional tautomerism process were obtained. Also, HOMA aromaticity chancing graphics were drowned in mentioned process. The IR band assignments and the decompositions of potential energy for each band were done using theoretical calculations. 1H and 13C NMR chemical shifts analyses were performed by using GIAO NMR calculations with SCRF solvent model.
Changes in Quality Parameters of Deep Fat Fried Carrot Slices Under The Effect of Ultrasound Assisted Pre-Drying Process
Authors: Karacabey Erkan , Turan Merve Seçil
Published: March 2018

Oil absorption is
partially associated to the initial moisture content of frying material, thus
controlling the moisture level could result in decreased oil absorption during
frying with accompanying changes in other physical properties. As a result, in
the current study, in order to figure out the changes in moisture and oil
contents of fried carrot slices, the effects of process parameters of
ultrasound assisted pre-drying was examined. Additionally texture and color
preferences were studied. Any reduction in oil absorption was achieved by
U/S-predrying, whereas it was observed that there was an increase in brightness
(L*) value of carrot slices as well as generally a decrease in a* values
compared to the control group. Effect of temperature was found to be
significant over a* and L* values for all power levels. Additionally, no
statistically significant change was observed for the textural properties with
applied ultrasound power levels.
Investigation In Electrical And Thermal Efficiency Of An Active Cooling Photovoltaic Thermal (Pv/T) Solar System With Taguchi Method
Authors: Ömeroğlu Gökhan
Published: March 2018

In this study, an attempt was made to optimize the default parameters in various experiments to improve the performance and heat transfer properties of the flat plate solar collector using the Taguchi method. An experimental investigation was carried out using air as working fluid at certain speeds (3.3, 3.9 & 4.5 m/s) on a PV/T collector. In this study, experiments were conducted to investigate the effects of heat transfer characteristics on performance, and the results are evaluated, since the above parameters have a great effect on the performance and heat transfer properties of the flat plate solar collector. Test Design for experiments were the Taguchi L36 Orthogonal Array Design. Experiments were carried out using the results of the outlet temperature of the air, the electrical and thermal efficiency of the collector, and the design of experiments by Taguchi method. The results showed that the selected parameters in this study had a significant effect on the selected responses and the verification results showed a significant improvement in the performance characteristics of the flat plate solar collector. The obtained results were analyzed in the ANSYS fluent program.
FORMULASI KODE ETIK PENDIDIK DALAM PERSPEKTIF PENDIDIKAN ISLAM
Authors: Farhan Moh.
Published: March 2018

Being  Educator  is an honour profession in Islam. It is an essensial factor in the education system. Thus a dignity  and an authority of this profession have to be maintained by the educators. The way to keep the honour of this profession can be done by conducting  ethical codes as a guidence to conduct activities as the educators.In a modern era, an educator ethic has been formulated. However, it shows unoptimal to keep the educators’ dignity. Thus, a solution is needed to solve the problem. Part of the solution  from Islamic education scholars during Islamic education hystory is the genuin thinking of those scholars. They have formulated the educator’s ethics codes. From their thinking and ideas, there are three ethic codes that can be understood: The First:  related to the obligation to have a good intention as the educator by improving a quality of  “taqwa” to Allah SWT because teaching is a worship. The second:  the educators have to keep their  profession by improving the personality with a good character (Akhlak). The third,  keep improving the educators’ competences and professionalism.
IMPLEMENTASI MANAJEMEN SUMBER DAYA MANUSIA DI MAN YOGYAKARTA III
Authors: Sholihah Hidayatus
Published: March 2018

This study is aimed at revealing the functions of human resource management in MAN  Yogyakarta III (State Islamic Senior High School) that includes human resource planning, recruitment, selection and placement, training and development, performance appraisal, compensation,   health program,  teacher  and employee relation  and the effectiveness of  human resource  management.This study is a qualitative research. The subjects of this study are the principal, teachers, employees and students of MAN Yogyakarta III. The data were collected through participant observation, semi-structured interview and documentation. The technique employed to measure the data validity was triangulation. The research instrument was the researcher herself. The data were analyzed using interactive model consisting of three phases:  data reduction, data display, and verification.The findings show that MAN Yogyakarta III (1) arranges  human resource  planning based on the vision, however, it is not effective because madrasah has no right to plan; (2) recruits competent teachers and employees effectively through  news paper; (3) sets four types of effective selection: administration selection, academic selection, interview and micro teaching and positions the teachers and employees based on their academic qualification and competences; (4) implements effective   training  and  development  programs   in  accordance  with  the  teachers` and employees` needs such as sharing ideas and knowledge, comparative study, internal presentation,  evaluation and coordination; (5) appraises performance by checking the administration of teaching and supervision but the  implementation of performance appraisal is not effective. (6) gives the effective compensation for the teachers and employees  in accordance with their   status; (7) undertakes effective health programs by creating clean and healthy school  environment; (9) organizes some programs to establish  effective relationship between the teachers and  employees.
UPAYA MENINGKATKAN HASIL BELAJAR PENDIDIKAN AGAMA ISLAM (PAI) MENGGUNAKAN METODE HYPNOTEACHING BAGI SISWA KELAS VII C SMPN 1 LIMBANGAN KABUPATEN KENDAL TAHUN 2016/2017
Authors: As’ari Kasan
Published: March 2018

This study aims to find out what should be done to improve the learning outcomes of Islamic Teaching subject matters (PAI) by using hypnoteaching method for students of grade VII C of State Junior High School 1 Limbangan Kendal in 2016/2017 ineven semester.This research is a classroom action research that aims to improve the learning result of PAI in the classroom. The subject of the study were students of class VII C who had the lowest learning result.This research was conducted in three cycles. Each cycle used a model or research design Kemmis and Taggart which is consisting of four components namely planning, acting, observing, and reflecting. Data completion technique used test learning result technique, where there are two tests result of learning. Those are pre-test and post-test. The test in this research used formative test in the form of objective test, the test question manifested in multiple-choice form. Data analysis technique by comparing average result of learning test before and after action is done.The results of this research showed that hypnoteaching method can improve PAI learning result with indicators, there is enhancement on the average PAI learning result from pre-test by 70.06 increased to 73.91 in cycle I, increased again to 76.79 in cycle II and increased again to 78.94 in cycle III. KKM achievement also increased from precycles of 36.36% to 60.61% incycle I, increased again to 72.73% incycle II and increased again to 81.82% during cycle III. From the result, there has been a significant improvement in the result of cycle III, so hypnoteaching method can be standardized into a model to improve the results of learning PAI with the following actions: 1. Affirmation by saying yells that involved the body movement and emotion, 2. Visualization by presenting something in the shadow alongside the members' body movement, 3. Reciprocation by peer tutoring in a group, 4. Invitation the students to be grateful for the knowledge Allah has given.
POLA PENYIMPANGAN MUSLIM TERHADAP AJARAN AGAMANYA ( Perspektif Pendidikan Islam)
Authors: Sholeh Muhammad Muhtar Arifin
Published: March 2018

Muslims in Indonesia and all over the world have the guidance regarding moral, which is clearly mentioned in the Quran and Sunnah (the prophet tradition). They have the written value, which is directly or indirectly used as a guidance. Nevertheless, the reality shows that those great values are not always done and realized in the real life of society. Religious and cultural teaching is only as a cognitive consumption (as knowledge), no realization, so that affective and psychomotor aspects are ignored.Behaviour of society which is far from the believed values will deviate from religious teaching. The paper discusses the problems of why Muslims deviate from their religious teaching, and of what factors which affect the deviation.The deviation done by Muslims are as follows; they do not understand their religious teaching, do not pray, do not fast in Ramadhan month, do not pay zakat, do not wear Islamic cloth. The factors affecting deviation of religious teaching are personality factor (laziness, no interest, no action), economy factor (poverty, work hard, money oriented), academic (knowledge) factor (no study, no understanding), and environmental factor (relation to family, neighbour, friends, and society).
PEMAKNAAN MIN AL-DHULUMAT ILA AL-NUR DALAM USAHA TRANSFORMATIF LEMBAGA PENDIDIKAN ISLAM
Authors: Muslim Moh.
Published: March 2018

The effort to develop an Islamic educational institution can not only be built on the concept of Aqliyah theory, but also based on the concept of God revelation. One of the explicit messages of God revelation is the phrase min adhulumatilaannur (from the darkness to the lightness). Implicitly, this phrase implies a transformation process from dhulumat (darkness) to an-nur (lightness). The process of transformation needs to be elaborated intact and holistic, how to interpret it; which will be formulated into the implementative formulation of the phrase.The phrase min al dhulumat ila an-nur conceptually there are three dimensional meaning that includes: 1). Textual, textual meaning of min al-dhulumatilaannur is from the darkness to the lightness, 2). Contextual, contextual meaning of min al-dhulumatilaannur; there are some interpretations from the interpreter whose essence is changing from disbelief to the faith, from apostasy to the faith, from ignorance to knowledge, and 3). Reconceptualization, there is a relevance of the concept min al-dhulumatilaannur with the management of education,that related to the transformation process that must be done to accept a change.Actualization of transformation can be done on some basic elements of education, i.e., students, teachers, headmasters/ managers, supervisors, employees and parents.
TERJEMAHAN AL-HURÛF AL-MUQATHTHA‘AH VERSI INKAR AL-SUNNAH: Telaah Kritis Al-Qur`an dan Terjemah Versi Tadabbur
Authors: Hasan Moh. Abdul Kholiq , Hidayat Syamsul
Published: March 2018

Abstrak:  Penelitian ini mengkritisi al-Hurûf al-Muqaththa‘ah dalam buku al-Qur’an dan Terjemah Versi Tadabbur. Penelitian ini merupakan penelitian semantik kualitatif berbasis kepustakaan, dengan menggunakan metode deskriptif dan content analysis. Hasil penelitian menunjukkan bahwa Minardi Mursyid menggunakan tiga pendekatan dalam menerjemahkan al-Hurûf al-Muqaththa‘ah. Pertama, pendekatan fonetik Arab berupa bunyi dasar suara yang terdapat pada al-Hurûf al-Muqaththa‘ah. Kedua, pendekatan tematik dengan cara mengumpulan ayat-ayat lain yang ada kaitannya dengan al-Hurûf al-Muqaththa‘ah yang diterjemahkan. Ketiga, pendekatan matematik dengan memakai rumusan angka 19 temuan Rasyâd Khalîfah. Penulis menyimpulkan bahwa dari ketiga pendekatan tersebut terdapat deviasi kaidah penafsiran dan bahasa Arab.

 Abstract: Translation of al-Hurûf al-Muqaththa‘ah of Inkar al-Sunnah Version: a Critical Study of Minardi Mursyid’s al-Qur`an dan Terjemah Versi Tadabbur . This study aims to criticize translation of al-Huruf al-Muqathttha'ah in Al-Qur’an dan Terjemah Versi Tadabbur. This research is text-based using semantic qualitative approach. This study reveals that Minardi Mursyid used three approaches in translating al-Huruf al-Muqaththa‘ah. The first approach was Arabic phonetic considering through basic sounds of al-Huruf al-Muqaththa‘ah. The second approach was thematic by collecting other verses related to the translation of al-Huruf al-Muqaththa‘ah. The third approach was mathematic using phenomenon of number 19 found by Rasyad Khalifah. The author affirms that the three above mentioned approaches had deviated from the principles of Quran exegeses and Arabic language.
 
Kata Kunci: Minardi, Inkar al-Sunah, al-Qur’an, al-Hurûf al-Muqaththa‘ah
INTERAKSI MUSLIM DAN KRISTIANI DALAM IKATAN KEKERABATAN DI SUMATERA UTARA
Authors: Irwansyah Irwansyah
Published: March 2018

Abstrak: Asumsi dasar yang dibangun pada penelitian ini adalah, hubungan muslim dan kristiani di Sumatera Utara berlangsung dalam berbagai domain dimana interaksinya bisa terjadi secara harmonis dan bisa pula disharmonis. Berpijak pada asumsi tersebut, permasalahan pada penelitian ini ditegaskan dalam pertanyaan “bagaimana hubungan muslim-kristiani di Sumatera Utara dalam ikatan kekerabatan?”. Penelitian dilakukan dengan menggunakan pendekatan Sosiologi Agama. Hasil penelitian menunjukkan bahwa hubungan muslim dan kristiani di Sumatera Utara pada domain kekerabatan berlangsung harmonis ketika keduanya mengalami interaksi yang berkesinambungan; melebur dalam berbagai aktivitas sosial; saling menghormati dan melahirkan kesadaran saling membutuhkan satu sama lain. Sementara hubungan disharmonis terjadi ditandai dengan sikap saling mencurigai, persaingan satu sama lain serta lahirnya konflik-konflik yang tersembunyi (hidden conflict).

Abstract: Muslim Christian Interaction within Kinship Tie in Sumatra Utara. The basic assumption of this study is that there has been a muslim and christian relations in North Sumatra in various domains, the interactions of which may occur in harmony, but also disharmony. Based on these assumption, the problem of this study is to answer the extent to which the muslim-christian relations occur in North Sumatra. Specifically, it traces the Muslims and Christians relations with regard to kinship. The study was conducted by using the socio-religious approach. The results of this study showed that the Muslim and Christian relations in North Sumatra, in the kinship domain run in harmony when both experienced continuous interaction, immerse themselves in various social activities, mutual respect and raise awareness of reciprocal relationship. While the disharmonious relationship occurred emanated from mutual suspicion, competition with one another and the hidden conflict.

Kata Kunci: Muslim, Kristiani, Sumatera Utara, interaksi agama-agama
POLA KERUKUNAN ANTAR UMAT BERAGAMA DALAM PERSPEKTIF FORUM KERUKUNAN UMAT BERAGAMA (FKUB) SUMATERA UTARA
Authors: Manshuruddin Manshuruddin
Published: March 2018

Abstrak: Penelitian ini bertujuan untuk memahami dinamika pola kerukunan umat beragama (religious harmony) FKUB di Sumatera Utara. Untuk mengungkap hal itu, penelitian ini menggunakan pendekatan phenomenologic-interpretif, dengan meng-gunakan teknik pengumpulan data pada FGD (Focus Group Discussion). Penelitian ini mengajukan beberapa temuan. Pertama, idealita kerukunan yang dibangun oleh FKUB Sumut berpijak pada pola kerukunan non-pluralisme agama, yang berarti bahwa truth claim pada masing-masing agama tidak bisa disamakan karena memiliki landasan teologis yang berbeda. Namun dalam konteks sosial, kebenaran teologis tersebut tidak boleh dipaksakan kepada orang lain, dan setiap individu beragama harus mampu bekerjasama untuk kepentingan bermasyarakat, berbangsa dan bernegara. Kedua, dalam penerapannya, FKUB Sumatera Utara melakukan dialog teologis, interaksi sosial, advokasi dan regulasi serta dialog interaktif.

Abstract: The Pattern of Religious Harmony in the Perspective of Religious Harmony Forum of Sumatera Utara. This study aims to analyze the dynamics of the harmony of the FKUB (Religious Harmony Forum in North Sumatra). This study uses a phenomenologic-interpretive approach, using data collection techniques in FGD (Focus Group Discussion). This research finds that: First, the ideal of harmony established by FKUB of North Sumatra is based on the pattern of religious non-pluralism harmony, in a sense that the claim of truth in each religion can not beequated because it has a different theological foundation. But in the social context, such theological truths should not be imposed on others, and every religious individual must be able to work together for the benefit of society, nation and state. Second, in its application, FKUB of North Sumatra conducts theological dialogue, social interaction, advocacy and regulation and interactive dialogue.

Keywords: agama-agama, kerukunan, pluralisme, FKUB, Sumatera Utara
Синтез и антибактериальная активность 3,6-диарил-7H-[1,2,4]триазоло[3,4-b][1,3,4]тиадиазинов
Authors: Ирадян Мелкон Арпиарович , Ирадян Н. С. , Минасян Н. С. , Пароникян Р. В. , Степанян Г. М.
Published: March 2018

Взаимодействием 4-амино-5-(2-алкоксифенил)-4H-[1,2,4]триазол-3-тиолов с замещенными фенацилбромидами синтезированы 6-(2’-алкоксифенил)-3-арил-7H-[1,2,4]триазоло[3,4-b][1,3,4]тиадиазины. На основании данных биологических испытаний выявлена взаимосвязь между химической структурой и антибактериальной активностью в ряду указанных триазолотиадиазинов.
Тропоксин — новое средство для лечения мигрени
Authors: Ганьшина Т. С. , Горбунов А. А. , Гнездилова А. В. , Турилова А. И. , Косточка Л. М. , Пятин Б. М. , Авдюнина Н. И. , Грушевская Л. Н. , Мирзоян Рубен Симонович
Published: March 2018

Разработано новое противомигреневое средство — тропоксин (3-(3,4,5-триметоксибензоилоксиимино)-8-метил-8-азабицикло[3,2,1]октана гидрохлорид), которое предупреждает или значительно ослабляет констрикторные реакции мозговых сосудов, вызванные серотонином (5-HT) или агонистом 5-HT2B/2C-рецепторов — мета-хлорфенилпиперазином (m-CPP) у животных интактных и в условиях ишемического поражения мозга. Препарат проявляет аффинность к 5-HT2 типа рецепторам мозга и оказывает антиагрегационное действие. Он не обладает выраженными нейротропными свойствами и не изменяет реакции артериального давления на норадреналин, ацетилхолин и гистамин. Пилотное клиническое исследование тропоксина свидетельствует о его высокой эффективности при межприступном лечении частых и тяжелых приступов мигрени.
Результаты экспериментального изучения иммунотропного действия полипренолов, выделенных из Alcea nudiflora
Authors: Сыров В. Н. , Вайс Е. В. , Хидырова Н. К. , Рахматова М. Д. , Шахидоятов Р. Х. , Хушбактова З. А.
Published: March 2018

Рассмотрен способ выделения полипренолов из Alcea nudiflora и их иммунотропное действие. Показано, что при введении полипренолов из Alcea nudiflora мышам одновременно с иммунизацией их эритроцитами барана наблюдается заметное стимулирование процесса первичного антителообразования, проявляющееся увеличением в селезенке количества антителообразующих клеток. Кроме того, отмечено увеличение клеточности центральных и периферических органов иммунитета, содержания эритроцитов и лейкоцитов в крови. Иммуностимулирующее действие полипренолов из Alcea nudiflora проявляется не только у нормальных животных, но и животных с вторичными иммунодефицитными состояниями, развивающимися при остром токсическом гепатите и облучении их в сублетальной дозе. По своей активности в проведенных экспериментах полипренолы из Alcea nudiflora не уступали известному иммуностимулирующему средству иммуналу.
Опиоидные κ-Рецепторы как молекулярная мишень для создания нового поколения обезболивающих лекарственных средств
Authors: Гречко Олеся Юрьевна , Спасов Александр Алексеевич , Штарёва Дарья Михайловна
Published: March 2018

В обзоре кратко описаны основные особенности строения и функций каппа-опиоидного рецептора, приведена характеристика его агонистов и перспектива их использования в медицине. Из всех подтипов опиоидных рецепторов именно κ-рецепторы являются наиболее привлекательными для создания новых препаратов с минимальным количеством нежелательных эффектов. Опиоидный κ-рецептор — представитель суперсемейства метаботропных G-белок сопряженных рецепторов. Опиоидные κ-рецепторы широко представлены как в ЦНС, так и на периферии. Они вовлечены в многочисленные физиологические процессы, включая анальгезию, регуляцию нейроэндокринной секреции, водного баланса, питьевого и пищевого поведения, вегетативных функций, механизмов обучения, памяти. На сегодняшний день имеется информация о существовании 3 подтипов κ-опиоидных рецепторов, но изученной является лишь молекулярная характеристика первого подтипа (κ1).
Особенности определения стерильности различных групп твердых лекарственных препаратов для парентерального применения
Authors: Гунар Ольга Викторовна , Сахно Надежда Геннадьевна , Рощина Марина Владимировна
Published: March 2018

Представлен информационно-аналитический обзор, посвященный методам определения стерильности твердых лекарственных форм препаратов. Проведен анализ действующей нормативной документации, регламентирующей качество парентеральных лекарственных средств (ЛС), описаны основные ограничения метода испытания по данному показателю. Определена вероятность обнаружения микроорганизмов в зависимости от доли контаминированных единиц в серии и количества образца для анализа. Представлены результаты анализа данных Государственного реестра ЛС о номенклатуре препаратов в твердой лекарственной форме и области их применения. Описаны особенности испытания отдельных фармакологических групп препаратов.
Выбор оптимальных параметров разделения аминокислот в тонком слое сорбента
Authors: Тринеева Ольга Валерьевна , Сливкин Алексей Иванович , Сафонова Елена Федоровна
Published: March 2018

Показана возможность теоретического подхода к выбору оптимальных условий разделения некоторых аминокислот в тонком слое сорбента, т.е. возможность прогнозирования значения величин Rf по уравнениям линейных зависимостей при известном значении полярности элюента. При совместном определении для достижения оптимальных величин Rf и наилучшего разделения следует работать в интервале от 5,13 до 5,69 единиц полярности системы. На основе установленных закономерностей, приведенных в работе, могут быть разработаны различные методики, которые в зависимости от целей анализа и предполагаемого состава аминокислот найдут применение в контроле качества как моно-, так и комбинированных аминокислотных препаратов, витаминных комплексов четвертого поколения, а также для разделения и идентификации свободных аминокислот, присутствующих в лекарственном растительном сырье и фитопрепаратах.
Влияние молярного замещения на подвижность макромолекул гидроксиэтилкрахмалов в растворе
Authors: Моисеев Сергей Владимирович , Кузьмина Наталия Егеньевна , Крылов Владислав Игоревич , Яшкир Вадим Анатольевич , Меркулов Вадим Анатольевич
Published: March 2018

С целью изучения влияния молярного замещения гидроксиэтилкрахмалов на подвижность макромолекул в растворе методом диффузионно-упорядоченной ЯМР-спектроскопии (1H-DOSY) измерены средние коэффициенты самодиффузии гидроксиэтилкрахмалов с различной степенью модификации амилопектина. Показано, что молярное замещение гидроксиэтилкрахмалов оказывает обратный эффект на подвижность макромолекул по сравнению с ветвлением полимерной цепи. Установлена неоднотипность стандартных образцов и лекарственных субстанций гидроксиэтилкрахмалов по значениям молярного замещения. Показано, что включение дополнительного параметра – молярного замещения в регрессионное уравнение позволяет повысить точность определения молекулярной массы гидроксиэтилкрахмалов транспортными методами аналитической химии.
Получение, токсичность и противовоспалительная активность комплексных соединений производных урацила с полифункциональными кислотами
Authors: Зимин Юрий Степанович , Борисова Наталья Сергеевна , Тимербаева Гузель Рамилевна , Гимадиева Альфия Раисовна , Мустафин Ахат Газизьянович
Published: March 2018

Показано, что производные урацила (6-метилурацил, 5-гидрокси-6-метилурацил) образуют с полифункциональными кислотами (цитрусовым пектином, окисленной фракцией цитрусового пектина и 5-аминосалициловой кислотой) достаточно устойчивые комплексные соединения состава 1:1, т.е. на 1 карбоксильную группу полифункциональной кислоты приходится 1 молекула урацила. На основании полученных результатов разработаны методики синтеза названных комплексов и изучена их токсичность и противовоспалительная активность. Установлено, что комплексные соединения 6-метилурацила с окисленной фракцией цитрусового пектина и 5-гидрокси-6-метилурацила с 5-аминосалициловой кислотой обладают малой токсичностью и повышенной противовоспалительной активностью.
Химико-фармакологическое изучение растительных сборов, улучшающих когнитивно-мнестические функции
Authors: Шилова Инесса Владимировна , Суслов Н. И. , Отмахов В. И. , Зибарева Л. Н. , Самылина И. А. , Мазин Е. В. , Петрова Е. В. , Бабушкина М. С. , Ковалева Т. Ю. , Кускова И. С. , Крапивин А. В.
Published: March 2018

Установлено, что отвары растительных сборов, содержащих траву лабазника вязолистного, побеги черники обыкновенной и зеленые листья бадана толстолистного, улучшают когнитивно-мнестические функции, нормализуя условно-рефлекторную деятельность и показатели ориентировочно-исследовательского поведения животных после гипоксического воздействия. Отвар сбора II, содержащего превалирующее количество лабазника, в дозе 5 мл/кг проявляет наибольшую активность. Количественное содержание флавоноидов в пересчёте на рутин в отварах сборов I и II составляет (0,22 ± 0,007) и (0,36 ± 0,011) мг/мл соответственно. В золе сбора II и его отвара, проявляющего выраженную активность, обнаружено 22 элемента, включая 15 эссенциальных или условно эссенциальных. В сборе II преимущественно содержатся K, Ca, Na, Mg, Si, P, Fe и Mn, а в отваре доминируют Ca, Mg, K, Na, P, Si, Mn и Zn. Примечательным является накопление в отваре в высокой концентрации B, P, Mg и Mo.
Сравнительное исследование химического состава настоек гомеопатических матричных подснежника Воронова (Galanthus woronowii Losinsk.) и подснежника белоснежного (Galanthus nivalis L.) методом газовой хроматографии с масс-селективным детекторо
Authors: Боков Дмитрий Олегович , Самылина Ирина Александровна
Published: March 2018

Проведено сравнительное исследование химического состава настоек гомеопатических матричных (НГМ) 2 видов подснежника — подснежника Воронова (Galanthus woronowii Losinsk.) и подснежника белоснежного (Galanthus nivalis L.) — методом газовой хроматографии с масс-селективным детектированием (ГХ-МС). В НГМ подснежника Воронова идентифицировано 13 соединений, в НГМ подснежника белоснежного — 42 соединения. Общими компонентами 2 настоек стали этил-α-D-глюкопиранозид, этил-α-D-рибозид, этиловый эфир линолевой кислоты и 2,3-дигидро-3,5-дигидрокси-6-метил-4H-пиран-4-он. Определены основные маркерные соединения (галантамин и ликорин), по содержанию которых предусмотрена стандартизация гомеопатических лекарственных средств.
Критерии взаимозаменяемости медицинских препаратов левофлоксацина в Российской Федерации
Authors: Кочеровец В. И. , Бунятян Наталья Дмитриевна , Олефир Ю. В. , Аляутдин Р. Н. , Романов Б. К. , Прокофьев А. Б.
Published: March 2018

Целью настоящего исследования являлся поиск информативных критериев нормативного регулирования процедуры определения взаимозаменяемости медицинских лекарственных препаратов (ЛП) левофлоксацина системного действия, зарегистрированных в Российской Федерации. Проведено сравнительное изучение химико-фармацевтических характеристик вспомогательных веществ 26 коммерческих препаратов левофлоксацина (таблетки, покрытые пленочной оболочкой для приема внутрь), а также проанализирована их номенклатура и инструкции по медицинскому применению. Показано, что имеются значительные различия в составе таблеток левофлоксацина, представленные на рынке Российской Федерации. Установлено, что разработка и внедрение информативных критериев нормативного регулирования процедуры определения взаимозаменяемости медицинских ЛП левофлоксацина должны способствовать проведению экспертизы качества ЛС при определении взаимозаменяемости ЛП для медицинского применения.
Применение фотогенерированного йода для определения натрия тиосульфата в инъекционном растворе
Authors: Турусова Елена Васильевна , Насакин Олег Евгеньевич , Лыщиков Анатолий Николаевич
Published: March 2018

Предложена методика ускоренного определения натрия тиосульфата в инъекционном растворе, основанная на титровании действующего вещества фотогенерируемым йодом. Титрант получали в результате облучения поглотительного раствора, содержащего йодид калия, ацетатный буферный раствор и эозин, в течение 1 – 2 мин. Нижний предел определения натрия тиосульфата составляет 0,20 мкг по силе тока и 0,32 мкг по времени генерации йода в поглотительной ячейке при ошибке, не превышающей 3,0 %. Применение данного способа определения натрия тиосульфата позволяет снизить время единичного определения.
Синтез и противомикробная активность 3-арил- и 3-арилметил-циклопента[c]пиразолов и циклопента[d]изоксазолов
Authors: Пантюхин Алексей Александрович , Михайловский Александр Георгиевич , Одегова Татьяна Фёдоровна , Першина Наталья Николаевна
Published: March 2018

Ацилированием 1-пиперидиноциклопентена хлорангидридами ароматических и арилуксусных кислот синтезированы соответствующие 1,3-дикетоны. Полученные дикетоны реагируют с гидразингидратом с образованием 3-арил- и 3-арилметил-циклопента[c]пиразолов и с гидроксиламином с образованием циклопента[d]изоксазолов. Дикетоны и полученные из них гетероциклические соединения проявили слабую ингибирующую активность в отношении Staphylococcus aureus и Escherichia coli. Самым активным оказался исходный дикетон, содержащий нитрогруппу в пара-положении, обладающий минимально ингибирующей концентрацией 125 мкг/мл.
Этиловый эфир N-фенилацетил-глицил-L-пролина метаболизируется до цикло-L-пролилглицина, проявляя сходный спектр нейропсихотропной активности
Authors: Гудашева Татьяна Александровна , Колясникова Ксения Николаевна , Кузнецова Елена Александровна , Литвинова Светлана Александровна , Золотов Николай Николаевич , Воронина Татьяна Александровна , Островская Рита Ушеровна , Середенин Сергей Борисович
Published: March 2018

Ранее сконструированный в качестве пептидного прообраза пирацетама цикло-L-пролилглицин (ЦПГ) обнаружен нами в мозге крыс в качестве эндогенного соединения, обладающего свойствами ноотропа и анксиолитика. В настоящей работе синтезирован этиловый эфир N-фенилацетилглицил-L-пролина (ГЗК-111). Показано, что ГЗК-111 метаболизируется до ЦПГ и проявляет ноотропную, анксиолитическую и антигипоксическую виды активности, характерные для ЦПГ, в дозах 0,1 – 1,5 мг/кг внутрибрюшинно. Эффекты ГЗК-111, как и ЦПГ, стереоселективны. Активны только L-энантиомеры. ГЗК-111 рассматривается как пролекарство, стимулирующее когнитивные функции, с анксиолитическим компонентом действия.