bluuebunny/crossref_metadata_2025 huggingface dataset:
Estrategias didácticas que utilizan los docentes de inglés para el uso y disfrute del aprendizaje en el inglés
Authors: Cock Martínez Juan Darío
Published: October 2023

Este artículo se deriva de una investigación denominada Estrategias didácticas que utilizan los docentes de inglés para el uso y disfrute del aprendizaje en el mismo. Parte de la necesidad de identificar las estrategias didácticas innovadoras para la enseñanza y aprendizaje del idioma. En la metodología se hizo una apuesta de investigación cualitativa desde la perspectiva de revisión documental, recurriendo a bases de datos especializadas como Redalyc, Dialnet, Scielo, Ebsco y Google académico. En relación con los resultados, se encuentra que hay una pérdida del vínculo de la motivación por el aprendizaje del inglés, porque el contexto escolar tiende a convertirse en el único lugar donde el niño puede construir y practicar una idea del inglés, la cual está vinculada a la experiencia de aula que no se trasversaliza con otros entornos sociales y por tanto la enseñanza y el aprendizaje del inglés, se ven limitados por las estrategias didácticas que se implementan en el contexto escolar.
La memoria del amor: procesos transactivos en parejas jóvenes que se comunican por WhatsApp
Authors: Arango Gallego Juan Mariano , Tejada Galeano Juan Pablo , Mejía Zapata Sandra
Published: October 2023

Objetivo: La investigación tuvo como fundamento principal comprender la influencia de la memoria transactiva en las relaciones de pareja mediadas por Whatsapp en los adultos jóvenes estudiantes de psicología de la Universidad Católica Luis Amigó sede Medellín. Método: Esta investigación tuvo una orientación cualitativa con enfoque fenomenológico, Como técnicas de recolección de información se emplearon rastreo bibliográfico y entrevista a profundidad, las cuales fueron codificadas posteriormente por medio del programa Atlas-Ti.9. Resultados: Una vez recolectada y analizada la información se procedió a triangular la información suministrada por los entrevistados a partir de la construcción de una matriz de principios asociacionistas y una matriz analítica. Conclusiones: a partir de los hallazgos se concluye que existe una relación entre los aspectos extensivos de la mente y las nociones mnésicas de una memoria transactiva alrededor de la construcción de los vínculos en torno del uso de la aplicación Whatsapp, demostrando que el uso de la tecnología ha cambiado de manera sustancial la forma como se constituyen las nociones biográficas en el desarrollo histórico de la pareja.
Cultura(s) e identidad(es): categorías para comprender el lugar del OTRO en la investigación del Trabajo Social
Authors: Pérez Álvarez Alexander
Published: October 2023

Este artículo tiene como propósito situar en términos epistemológicos y ontológicos una discusión que por momentos ha estado instrumentalizada en los debates actuales de la investigación en el Trabajo Social y en general en las ciencias sociales.  En ese sentido interroga y reflexiona ese lugar de la otredad desde tres lugares o perspectivas teórico-ético-políticas. El primero referido a una crítica que legitima la idea de la cultura e identidad en singular, una perspectiva dominocéntrica que homogeniza y exotiza la otredad y/o la constituye como esencia cultural. En segundo lugar, la cultura y la identidad asumidas como fragmentos en una mirada dicotómica arbitraria que separa y sustancializa las ideas de naturaleza y cultura. Y, por último, ubicamos una vertiente configuracionista y situacional desde la cual es posible comprender órdenes simbólicos en una perspectiva histórica donde se supere la mirada del otro como un simple individuo enajenado de los órdenes y estructuras de poder.
Mathematical, algorithmic and software support of synphase detection of radio signals in electronic communication networks with noises
Authors: Khvostivska Liliia , Khvostivskyi Mykola , Dunets Vasyl , Dediv Iryna
Published: October 2023

Mathematical (radio signal model as a periodically correlated stochastic process and synphase method of its processing) and algorithmic support for synphase detection of stochastic-periodic radio signals in electronic communication networks with noise by calculating new detection indicators in the form of correlation components, which ensure effective making a decision regarding the presence or the absence of a useful radio signal in obstacles of different power. For a more detailed assessment of the calculated indicators of radio signal detection in the form of correlation components, were used averaged estimates. Software for synphase detection of radio signals in electronic communication networks with a graphical user interface is implemented in the Matlab environment. The process of synphase detection of radio signals in electronic communication networks with noise was investigated and the effectiveness of the application of new detection indicators was ascertained.
Modeling of undeformed chip in power skiving gear cutting process
Authors: Andrii Slipchuk
Published: October 2023

The method of cutting gear wheel by the Power skiving method is considered and the principle of creating non-deformed chip when cutting external spur gear is analyzed in detail in this paper. The task of this investigation is to develop an adequate model of chip formation and to analyze quantitative estimates of parameters of slices in Power skiving process. In order to solve this problem, complex system of grapho-analytical, mathematical and computer modeling of this process is developed. It takes into account its kinematics and reliably reproduces the regularities of cutting-forming processes. The grapho-analytical method developed by I. E. Hrytsai for worm tooth milling is used to model the parameters of the sections. The continuous movement of cutting and forming is presented in the form of successive discrete movements of the contour of the tooth, and its linear and angular positions relative to the processed gear wheel are easily described mathematically. This greatly simplifies the model and geometric constructions using existing CAD systems, unlike other known methods. In each position of the tooth, its contour in the front surface is combined with the contours of the teeth, which performed cutting in the previous positions both along the axial feed and on the helical line. The main condition for the accurate determination of the parameters of the cuts is the establishment of the shape and dimensions of the surface, which is formed in the process of steady cutting in each cavity of the gear wheel between the treated surfaces of the teeth and the raw surface of the workpiece for 1 revolution of the cutter. To investigate the parameters of the slices, the schematic arrangement of the gear wheel and the cutter is depicted and the process is divided into discrete states. The results of modeling according to the above mentioned parameters are given in the form of graphic dependencies: chip cross-sectional area, thickness depending on different axial feeds of the cutter and for different modules of the gear wheel. The dependence of the change in the geometric characteristics of the undeformed chip on the position of the cutter is obtained. In further research, it is possible to establish a number of other physical quantities and their interdependence during gear cutting using the Power skiving method.
Aplicación del enfoque 6D BIM en la evaluación y propuesta de rehabilitación energética en la infraestructura educativa pública
Authors: Sánchez-Ramón David , Costa-De los Reyes Claudia
Published: October 2023

INTRODUCTION. When approaching the design of a building, one of the primary objectives is to create an interior environment that promotes the health and comfort of its occupants. OBJECTIVE. The research seeks to evaluate through 6D BIM the energy performance of the prototype educational infrastructure built in Ecuador, in a case of the city of Loja, in order to know the comfort parameters, compare them with what is exposed by the normative bases and propose an energy rehabilitation proposal to improve comfort and reduce the energy consumption of the building. METHOD. The process is carried out through virtual test-tube simulation in Revit software and its simulation engine EnergyPlus to know its energy performance. Based on this, strategies to improve thermal and lighting comfort and air quality in the building are proposed and validated. RESULTS. The results show that the equipment does not comply with the comfort ranges according to the zone where it is located, with an interior temperature of 17.88°C, lighting levels of 3500 lumens, RH of 60% and 51 MWh/y of electricity consumption. DISCUSSION AND CONCLUSIONS. The proposed intervention has demonstrated significant improvements, including an increase in temperature by 6.18°C, a reduction of 2300 lumens in lighting, a 10% decrease in relative humidity (RH), and reduced electrical consumption to 42 MWh/a. These results consolidate this intervention as a highly replicable and energy efficient alternative for similar infrastructures.
Pengaruh Kecerdasan Intelektual Dan Kecerdasan Emosional Terhadap Kinerja Karyawan
Authors: Karambut Christien , Jacob Tateol Silangen Makapedua  , Daisy Iriany Erny Sundah  , Grace Joice Silvana Neltje Rumimper
Published: October 2023

One way to produce good employee performance is to have adequate intellectual intelligence. Employee performance is influenced by ability. Ability is not only about knowledge but also skills. Ability in the form of knowledge can be formed through education and experience, while skills are formed from exercises. One of the skills that employees can manage themselves is emotional intelligence. EmotOne way to produce good employee performance is to have adequate intellectual intelligence. Employee performance is influenced by ability. Ability is not only about knowledge but also skills. Ability in the form of knowledge can be formed through education and experience, while skills are formed from exercises. One of the skills that employees can manage themselves is emotional intelligence. Emotional intelligence can help someone in using their cognitive abilities (knowledge) according to their maximum potential. Emotional intelligence needs to be developed in order to have a positive impact on improving employee performance. The purpose of this study was to determine the effect of intellectual intelligence and emotional intelligence on employee performance either partially or simultaneously. The sample in this study were graduates of the Manado State Polytechnic Department of Business Administration which collected 114 respondent. The sampling technique used convenience sampling and data analysis with multiple regression using SPSS. The results showed that there was a significant influence between intellectual intelligence on employee performance and emotional intelligence on employee performance partially. In addition, intellectual intelligence and emotional intelligence simultaneously affect employee performanceional intelligence can help someone in using their cognitive abilities (knowledge) according to their maximum potential. Emotional intelligence needs to be developed in order to have a positive impact on improving employee performance. The purpose of this study was to determine the effect of intellectual intelligence and emotional intelligence on employee performance either partially or simultaneously. The sample in this study were graduates of the Manado State Polytechnic Department of Business Administration which collected 114 respondent. The sampling technique used convenience sampling and data analysis with multiple regression using SPSS. The results showed that there was a significant influence between intellectual intelligence on employee performance and emotional intelligence on employee performance partially. In addition, intellectual intelligence and emotional intelligence simultaneously affect employee performance
Strategi Pengelolaan BUMDes Amarta Dalam Penguatan Ekonomi Desa Pandowoharjo
Authors: Kurata Rahma Aulia  , Nur Ameliah Ispi  , Winda Irmayani
Published: October 2023

Amarta BUMDes located in Pandowoharjo Village, Sleman Regency. BUMDes Amarta Pandowoharjo Village was established on June 6 2016 and stipulated in Pandowoharjo Village Regulation Number 04 of 2016 concerning the Formation and Management of BUMDes. BUMDes Amarta has five business units and has collaborated with various partners including Bank BRI, Sampoerna, Indonesian Swimming Association and jeJamuran. The method used in this research is descriptive qualitative. Data collection techniques were carried out through participating observations. The results of the study show that the strategy used by BUMDes is able to strengthen the economy of Pandowoharjo Village by increasing the village's original income with a profit sharing system between the manager and the village, BUMDes provides 35% of the profits derived from several business results of the Amarta BUMDes unit for PADes.
Pengaruh Konten Review, Kualitas Produk, Dan Gaya Hidup Terhadap Minat Mahasiswa Menggunakan Fashion Produk Lokal
Authors: Dewa Dhana Berlyan Reksa , Warnaningtyas Hartirini , Istiqaroh Choirum Rindah
Published: October 2023

This study aims to examine and determine the effect of review content, product quality, and lifestyle on students' interest in using local products fashion. The population in this study were students of the Faculty of Economics, Merdeka Madiun University, users of local products fashion. The sample size in this study was 152 people. The method used in sampling is purposive sampling. The research instrument used a questionnaire. Data analysis techniques used the classical assumption test, multiple linear regression analysis, analysis of the coefficient of determination, and hypothesis testing using the t test and F test. The results showed that the content review variable partially had a significant effect on students' interest in using local products fashion, product quality variables partially has a significant effect on students' interest in using local products fashion, lifestyle variables partially have a significant effect on students' interest in using local products fashion, and simultaneously the review content variables, product quality, and lifestyle have a significant effect on students' interest in using local products fashion.
Novel tissue thickening around the notochord sheath found in deformed Japanese eel Anguilla japonica leptocephali
Authors: Okamura A , Yamada Y , Mikawa N , Horie N , Tsukamoto K
Published: October 2023

Even though reared leptocephalus larvae of the Japanese eel Anguilla japonica have a high incidence of notochord deformities (>60%), the cause is unknown. We performed histological examinations of the notochord and associated organs in reared larvae to better understand the process causing notochord deformation in eel larvae. In deformed larvae, unknown tissue thickening was discovered near the notochord sheath. Azan staining revealed that these tissue thickenings are most likely collagen fibers within fibrous connective tissue. This was almost identical to the connective tissue found in the primordium of the vertebral body around the notochord sheath in properly metamorphosing larvae. Furthermore, the amount of the thyroid hormone triiodothyronine (T3) was significantly higher in deformed larvae than in normal larvae, indicating that notochord deformity is probably linked to metamorphosis despite the immature stage of growth. We suggest that the aberrant growth of connective tissue surrounding the notochord sheath induced by incomplete metamorphosis causes deformities in eel larvae. The reason why deformed larvae have greater thyroid hormone levels is still unknown. It is important to assess how environmental and dietary factors affect the thyroid hormone levels of eel larvae raised in captivity.
Inhalation Administration of Leytragin to C57BL/6Y Mice in an ARDS Model Increases the Expression Level of SIRT1 Gene
Authors: Ogneva N. S. , Taboyakova L. A. , Alimkina O. V. , Petrova N. V.
Published: October 2023

This paper describes a technique for inhalation administration of Leutragin into the lungs of C57BL/6Y mice in a model of acute respiratory distress syndrome (ARDS). Inhalations were carried out using an OMRON COMP AIR NE-C24 Kids compression inhaler with a nozzle for simultaneous administration to several mice, developed at the Scientific Center of Biomedical Technologies of FMBA of Russia. Modeling of ARDS was carried out by sequential administration of α-galactosylceramide, inhaled at a dose of 1 μg/mouse, and, following 24 hours, a combination of E. coli lipopolysaccharide (LPS) at a dose of 300 μg/mouse. Thirty minutes after the administration of LPS, inhalation administration of the Leytragin drug was carried out to mice in the experimental group and normal saline in the control group. After inhalation, a biomaterial (lung tissue) was collected to evaluate the expression of the SIRT1 gene by RT- PCR as a marker of successful penetration of the drug into the lung tissue.
Technique for Measuring Electrical Activity of the Brain in Experiments on Laboratory Animals
Authors: Tropskaya N. S. , Razbitskaya O. V.
Published: October 2023

This article presents a technique for experimental EEG analysis, which includes construction of a frequency spectrum trend, determination of the spectral power of signals in standard frequency ranges, followed by normalization by the maximum value in all channels and in all frequency ranges. This technique can be used to carry out a comparative analysis of data in any time interval, to evaluate the dynamics of changes in each of the main EEG rhythms, to identify the presence of a fronto-occipital gradient and interhemispheric asymmetry, and to evaluate the values of the integral index, which reflects the ratio of high- and lowfrequency rhythms.
Pengembangan Media Kartu Domino Materi Persamaan dan Pertidaksamaan Linear Satu Variabel (PLSV) Kelas VII SMP
Authors: Nurhidayati Dwi , Khabibah Siti , Saâ€™adah Nihayatus
Published: October 2023

One of the goals of using learning media is to improve the quality of student learning and make the learning process more interesting. Domino card learning media is one of the game innovations that can be used in the classroom. This study aims to describe the level of feasibility of domino card learning media on the material of Linear Equations and Inequality One Variables by adapting the ADDIE development model. The data collection technique used is a questionnaire. Questionnaires are divided into two types, namely validation questionnaires and student response questionnaires. The validation stage of learning media products is carried out by material experts, media experts, and learning practitioners. While the student response questionnaire with small group test subjects by three students and field trials by all students of class VII B. The validation results from material experts obtained an average score of 3.17 with a percentage of 63.3% and the criteria "Good" . Learning media experts obtained an average score of 4.45 with a percentage of 89.1% and the criteria "Very Good". Learning practitioners obtained an average score of 4.17 with a percentage of 83.3% and the criteria "Very Good". The response of students in the small group trial which obtained a score of 4.83 with a percentage of 96% and the criteria "Very Good". The response of students in the field trial which obtained a value of 4.45 with a percentage of 89.2% and the criteria "Very Good". So, it can be concluded that the domino card learning media on the One Variable Linear Equation and Inequality material is said to be very well used as a learning medium in the mathematics learning process.
PENGEMBANGAN LEMBAR KERJA PESERTA DIDIK (LKPD) BERBASIS GROUP INVESTIGATION PADA MATERI PENCEMARAN LINGKUNGAN KELAS VII SMP
Authors: Baiq Afifatul Adiyani  , Nindha Ayu Berlianti
Published: October 2023

Tujuan penelitian ini adalah menghasilkan LKPD berbasis group investigation materi pencemaran lingkungan kelas VII SMP dan mengetahui kelayakan LKPD sebagai bahan ajar. Jenis penelitian pengembangan ini mengacu pada model pengembangan ADDIE yaitu: Analysis, Desain, Development, Implementation dan Evaluation. Akan tetapi pada penelitian ini dibatasi hanya sampai pada tahap ketiga yaitu tahap pengembangan (Development). Instrumen yang digunakan dalam penelitian ini adalah lembar validasi dan lembar kepraktisan yang berupa angket respon peserta didik. Lembar validasi digunkan untuk mengetahui kualitas LKPD yang dikembangkan, sedangkan lembar angket respon peserta didik digunakan untuk mengetahui seberapa besar respon peserta didik terhadap LKPD yang dikembangkan. Hasil penelitian ini adalah produk berupa LKPD berbasis group investigation materi pencemaran lingkungan kelas VII SMP. Dari hasil analisis instrument validasi LKPD, LKPD yang dikembangkan berkategori sangat valid dengan tingkat kevalidan 87, 41%. Tingkat kepraktisan LKPD yang diperoleh dari penilaian peserta didik sebesar 90, 98% dengan kategori sangat praktis. LKPD berbasis group investigation dalam penelitian ini layak di implmentasikan.

Kata Kunci: Lembar kerja peserta didik (LKPD), Group investigation, pencemaran lingkungan
The Influence of Teaching Methods in Classroom Learning Ecological Environment on Self-Regulation of Junior High School Students
Authors: YU Luo
Published: October 2023

The classroom learning environment is a comprehensive entity composed of interpersonal relationships, rules and regulations, class ethos, material conditions, etc., and is an important component of classroom teaching. This study aims to explore the influence of teaching methods based on the classroom learning environment on middle school students’ self-regulated learning. Convenient sampling was used for the questionnaire survey, with 276 middle school students in China’s A city as the research subjects. The research results showed that teaching methods have a significant impact on middle school students’ self-regulated learning; teaching methods have a significant impact on the classroom learning environment; the classroom learning environment has a significant impact on middle school students’ self-regulated learning; the classroom learning environment plays an important role in the relationship between teaching methods and middle school students’ self-regulated learning.
The Role of Marketing and Digital Marketing Capabilities: Entrepreneurial Orientation on the Marketing Performance of Public Enterprises
Authors: KRISNANTO Aditya Budi , SURACHMAN Surachman , ROFIATY Rofiaty , SUNARYO Sunaryo
Published: October 2023

Public enterprises and small and medium enterprises (SMEs) have similar goals in the eyes of the state. SMEs that get government or public bodies funding can make it a public enterprise. These enterprises in Indonesia face challenges due to limited resources, low market reach, and low marketing expertise. They must leverage their marketing capabilities effectively and adopt strategic approaches such as entrepreneurial orientation and digital marketing. This study explores digital marketing mediation and marketing capabilities in the relationship between entrepreneurial orientation and marketing performance in public enterprises. Survey techniques were used for this study, and data were obtained from 176 respondents who are entrepreneurs who use social media in their marketing activities. Data are processed and analysed using smartPLS. The results of this study show that entrepreneurial orientation significantly affects marketing capabilities, digital marketing and marketing performance in MSEs. Digital marketing and market capabilities have a direct positive influence on marketing performance. In addition, digital marketing and market capabilities mediate the relationship between entrepreneurial orientation and marketing performance. Marketing capabilities mediate the relationship between digital marketing and marketing performance.
N-Acetylcysteine Ameliorates 5-Fluorouracil‐Induced Ovarian Injury in Rats
Authors: AYAZOGLU DEMİR Elif , MENTESE Ahmet , KÜÇÜK Hatice , TÜRKMEN Nihal , DEMİR Selim , ALİYAZICIOĞLU Yüksel
Published: October 2023

Objective: Although 5-fluorouracil (5-FU) is one of the most commonly used chemotherapeutics worldwide, it has been shown that 5-FU administration can cause reproductive toxicity in recent years. N-acetylcysteine (NAC) is the precursor of glutathione, the most important endogenous antioxidant molecule and is known for its effective antioxidant and anti-inflammatory properties. Although NAC is one of the most studied antioxidant molecules, its curative effect against ovarian damage caused by 5-FU has not been demonstrated to date. It was therefore aimed to investigate whether NAC is therapeutic against 5-FU-induced ovotoxicity in this study for the first time.

Methods: Rats were first exposed to a single dose of 5-FU (100 mg/kg) and then treated with NAC (10 and 20 mg/kg) for three days. The oxidative stress, inflammation and apoptosis markers in ovarian tissues were also determined using spectrophotometric methods. Ovarian tissues were also evaluated histologically.

Results: It was revealed that the levels of oxidative stress, inflammation and apoptosis biomarkers in ovarian tissue increased by 5-FU administration (p
Radiographic Evaluation of the Effect of Vitamin D3 Supplementation on Regeneration of Calvarial Bone Defects in Rats
Authors: VARLIHAN Gülce Nil , AĞRALI Ömer Birkan , YILDIRIM Hatice Selin , DEMİRCİ DELİPINAR Sibel , KURU Leyla , ÖZTÜRK ÖZENER Hafize
Published: October 2023

Aim: The present study was aimed to evaluate radiographically the effect of orally administered vitamin D3 on guided bone regeneration in calvarial critical size defects (CSD) in rats.

Methods: Two calvarial CSD were created in 12 male Sprague-Dawley rats. One of the defects was left empty (E defect), while the other one was treated with deproteinized bovine bone graft and collagen-based resorbable membrane (GM-filled defect). Following surgical intervention, rats were randomly assigned into two groups; the control group was administered distilled water, and the test group was treated with 2 µg /kg vitamin D3 by gavage once a day for 8 weeks. Radiological images were obtained from rats on 4th and 8th weeks. The area fraction of newly formed osteoid was determined using Image Fiji Analysis Software.

Results: The percentages of area fraction in the GM-filled defects were statistically higher than the E defects in both study groups at 4th and 8th weeks (p
A New Perspective on the Evaluation of Comorbidity Indices on Survival in Non-Small Cell Lung Cancer
Authors: BAKIR KAYI Alev , MÜSELLİM Benan
Published: October 2023

Objective: Mortality studies are interpreted by considering comorbid diseases related to the main disease. Existence, number, and type of comorbid diseases can have an important effect on prognosis. There are various comorbidity indices to include the effects of comorbid diseases in the model. With a new perspective, we aimed to emphasize the importance of evaluating the combination of comorbid diseases in cancer survival.

Methods: Retrospective cohort, data were collected from cases with Non-Small Cell Lung Cancer treated in Department of Chest Diseases. Initially, the effects of their comorbid diseases on the duration of survival were calculated with univariate analysis, then examined according to number of comorbidities, lastly their specific combinations' Hazar Ratio were calculated with Cox multivariate analysis. The most used comorbid indices in the literature were also included.

Results: Out of 247 non-small cell lung cancer (NSCLC) cases analysis, 220 (89%) were men. Median duration of follow-up was 277 days, at the end of the follow-up 197 cases had died. HR of two comorbid diseases in cases was 1.80, but 59.52 for the combination of “diabetes and interstitial lung disease” and 3.76 for “diabetes and previously cancer”. Existing comorbid indices had no significant effect on survival time (p:0.684; 0.101; 0.273; 0.567, respectively).

Conclusion: We have offered a new perspective which takes into comorbid diseases related to main disease and specially their combinations when the risk is estimated in survival research. Accurate assessments of the list of comorbid diseases related to main disease hold significant importance in advancing this field.
A Aproximação entre Economia Pós-Keynesiana e Economia Ecológica: apreciação crítica e considerações sobre o financiamento verde
Authors: Bispo Santos Luiz Henrique , Caixeta Andrade Daniel
Published: October 2023

Existem tentativas recentes de aproximação entre economia ecológica e economia pós-keynesiana, cujos esforços de síntese se dão num contexto de entrelaçamento de crises econômicas, sociais, políticas e ecológicas. A partir desta integração vem se consolidando uma nova disciplina chamada de macroeconomia ecológica pós-keynesiana. Este artigo procura recuperar este esforço de síntese a partir da análise dos núcleos duros da economia pós-keynesiana e economia ecológica. Em seguida, o artigo destaca a importância do financiamento verde, tema relativamente pouco explorado, principalmente por parte dos economistas ecológicos. A contribuição apresentada é a de argumentar que a aproximação entre a economia ecológica e a economia pós-keynesiana permite uma melhor compreensão e enquadramento do financiamento enquanto categoria analítica essencial para uma transição ecológica. Por fim, evidencia-se, ainda, o avanço do financiamento às atividades ambientalmente degradantes, a despeito dos alertas sobre a crise ecológica.
RANCANG BANGUN ALAT PENGERING SARANG BURUNG WALET MENGUNAKAN ARDUINO VIA SENSOR DAN TIMER
Authors: Korino Korino , Nopriadi Nopriadi
Published: October 2023

Swallow's nest is a material that provides great benefits, especially in relation to health and also as a profitable export/import commodity. However, it is not surprising that the swallow's nest business requires a lot of capital and swallow's nest products must be of high quality. Therefore, in swallow nest processing there are several important stages such as cleaning, shaping, drying and packing. From the above process, it is clear that the scale is a measure of water content which also affects the selling price, so a swallow hatcher is needed. The drying process greatly affects the quality of the swallow product/nest. If the swallow nest is too dry, there is a decrease in the weight of the material which can be dangerous. If it is too moist, mould will form and there may also be dirt. At this stage, drying is still done manually with the help of a fan. The fan is turned on for an hour, but sometimes the workers forget to turn off the fan, causing the swallow's nest to dry too much, which also results in a waste of electricity. The design of this dryer uses a sensor to turn on the lights and a timer to determine the time needed. With this tool can help workers in managing swallow nest dryers. The existence of this tool also helps businesses to be able to dry swallow nests automatically.

 

Keywords: Dryer, Sensor, Timer, and Arduino
Chimaeribacter arupi a new member of the Yersineacea family has the characteristics of a human pathogen
Authors: Riediger Matthias , Hoffmann Katharina , Isberner Riekje , Dreyer Annika , Tersteegen Aljoscha , Marquardt Pauline , Kaasch Achim J. , Zautner Andreas E.
Published: October 2023

Chimaeribacter arupi (heterotypic synonym: “Nissabacter archeti”) is a facultative anaerobic, newly described Gram-negative rod and belongs to the Yersineacea family. Here, we report the case of a 19-month-old female infant patient who presented to the emergency unit with somnolence and fever. C. arupi was isolated from a positive blood culture, taken via an implanted Broviac catheter, proving a bloodstream infection by the pathogen. The objective of this study was to utilize whole genome sequencing to assess the genes encoding potential virulence associated factors, which may play a role in host tropism, tissue invasion and the subsequent stages in the pathogenesis of a bloodstream infection with C. arupi. The genome of the isolate was completely sequenced employing Illumina MiSeq and Nanopore MinION sequencing and the presumptive virulence associated factors and antimicrobial resistance genes were investigated in more detail. Additionally, we performed metabolic profiling and susceptibility testing by microdilution. The presence of predicted TcfC-like α-Pili suggests that C. arupi is highly adapted to humans as a host. It utilizes flagellar and type IV pili-mediated motility, as well as a number of γ1-pili and a σ-pilus, which may be used to facilitate biofilm formation and adherence to host epithelia. Additionally, long polar fimbriae may aid in tissue invasion. The bacterium possesses antioxidant factors, which may enable temporary survival in phagolysosomes, and a capsule that potentially provides protection from phagocytosis. It may acquire iron ions from erythrocytes through the type 6 secretion system and hemolysins. Furthermore, the isolate exhibits beta-lactamase-mediated penicillin and aminopenicillin resistance. Based on the analysis of the whole genome, we conclude that C. arupi possesses virulence factors associated with tissue invasion and may thus be a potential opportunistic pathogen of bloodstream infections.
Cardiovascular sex-differences: insights via physiology-based modeling and potential for noninvasive sensing via ballistocardiography
Authors: Zaid Mohamed , Sala Lorenzo , Despins Laurel , Heise David , Popescu Mihail , Skubic Marjorie , Ahmad Salman , Emter Craig A. , Huxley Virginia H. , Guidoboni Giovanna
Published: October 2023

In this study, anatomical and functional differences between men and women in their cardiovascular systems and how these differences manifest in blood circulation are theoretically and experimentally investigated. A validated mathematical model of the cardiovascular system is used as a virtual laboratory to simulate and compare multiple scenarios where parameters associated with sex differences are varied. Cardiovascular model parameters related with women’s faster heart rate, stronger ventricular contractility, and smaller blood vessels are used as inputs to quantify the impact (i) on the distribution of blood volume through the cardiovascular system, (ii) on the cardiovascular indexes describing the coupling between ventricles and arteries, and (iii) on the ballistocardiogram (BCG) signal. The model-predicted outputs are found to be consistent with published clinical data. Model simulations suggest that the balance between the contractile function of the left ventricle and the load opposed by the arterial circulation attains similar levels in females and males, but is achieved through different combinations of factors. Additionally, we examine the potential of using the BCG waveform, which is directly related to cardiovascular volumes, as a noninvasive method for monitoring cardiovascular function. Our findings provide valuable insights into the underlying mechanisms of cardiovascular sex differences and may help facilitate the development of effective noninvasive cardiovascular monitoring methods for early diagnosis and prevention of cardiovascular disease in both women and men.
The impact of bilateral brachial-ankle pulse wave velocity difference on cardiovascular disease and all-cause mortality
Authors: Zheng Mengyi , Zhang Xinyuan , Zhao Quanhui , Chen Shuohua , Guo Xinying , Wang Chi , Jonas Jost B. , Wu Shouling , Guo Caixia
Published: October 2023

Background

This study aims to investigate the association between an elevated bilateral pulse wave velocity difference (BPWVD) and cardiovascular diseases (CVDs) and all-cause mortality.

Methods

This study included a total of 38,356 participants. A multivariable Cox proportional hazards regression was used to assess the association between high BPWVD and the increased risk of CVDs and all-cause mortality by calculating hazard ratios (HRs) with 95% confidence intervals.

Results

A total of 1,213 cases of CVDs were identified over a mean duration of 6.19 years, including 886 cases of cerebral infarction (CI), 105 cases of intracerebral hemorrhage (ICH), and 222 cases of myocardial infarction (MI), along with 1,182 cases of all-cause mortality. The median BPWVD was 42 cm/s (19–80 cm/s). After adjusting for all confounders and baseline brachial-ankle PWV (baPWV), our analysis revealed a significant correlation between a higher risk of CVDs, MI, and all-cause mortality with an increase in BPWVD per standard deviation. HRs (95% confidence interval) were found to be 1.06 (1.01–1.11), 1.11 (1.02–1.21), and 1.07 (1.04–1.10), respectively. Among the participants with higher baPWV on the left side, the HRs (95% confidence interval) were 1.08 (1.02–1.14) for CVDs, 1.27 (1.10–1.46) for incident ICH, 1.16 (1.00–1.24) for incident MI, and 1.10 (1.07–1.15) for all-cause mortality, for per standard deviation increase in BPWVD.

Conclusions

Our findings reveal a significant correlation between elevated BPWVD and the risks of developing CVDs and all-cause mortality. This highlights the importance of thoroughly evaluating BPWVD as a means of detecting individuals at risk for CVDs and mortality.
Closed-chest robotic repair of mitral prolapse. Surgical technique and early results
Authors: Sandoval Elena , Morales-Rey Ignacio , Bartolozzi Luis , Pereda Daniel
Published: October 2023

Background

Robotic mitral repair is generally performed with four intercostal trocars and a minithoracotomy. We describe our technique and results with a totally-thoracoscopic closed chest approach using a 12 mm valveless trocar as “working port”, without a minithoracotomy. We compared our results with this technique with a control group of robotic mitral repairs performed earlier with a minithoracotomy.

Methods

Review of all patients with degenerative mitral valve disease who underwent robotic mitral valve repair surgery since December 2019 (n = 110). Patients with concomitant procedures (n = 8) were excluded. The remaining 102 patients were divided in two groups, depending on the approach used, minithoracotomy (n = 63) and totally thoracoscopic (n = 39).

Results

There were no significant differences between groups regarding preoperative characteristics. All procedures were completed robotically as planned, and repair rate was 100%. The minithoracotomy group showed a higher percentage of leaflet resections (17.9% vs. 38.7%; p = 0.03). All surgical times were significatively reduced in the totally thoracoscopic group: Cardiopulmonary bypass (97 vs. 115 min, p = 0.0008), ischemic time (67 vs. 80 min, p = 0.0013) and total surgical time (185 vs. 225 min; p < 0.00001). There were no differences in ICU length of stay (1 day, p = 0.07) but hospital length of stay was shorter in the totally thoracoscopic group (4 days; p = 0.0001). Postoperative complications were similar between groups. MR at discharge was mild or less in all cases.

Conclusions

Robotic mitral repair for degenerative disease can be safely performed as a closed-chest procedure, using a 12 mm trocar as “working port” and avoiding the need for a minithoracotomy. This approach does not seem to negatively affect the quality of the procedure by any measure, providing similar excellent clinical outcomes and repair rate. All surgical times were shorter in the closed-chest group.
Hypercontractile cardiac phenotype in mice overexpressing the regulatory subunit PR72 of protein phosphatase 2A
Authors: Herting Julius R. , König Jule H. , Hadova Katarina , Heinick Alexander , Müller Frank U. , Pauls Paul , Seidl Matthias D. , Soppa Carolina , Kirchhefer Uwe
Published: October 2023

Background

The activity, localization, and substrate specificity of the protein phosphatase 2A (PP2A) heterotrimer are controlled by various regulatory B subunits. PR72 belongs to the B'' gene family and has been shown to be upregulated in human heart failure. However, little is known about the functions of PR72 in the myocardium.

Methods

To address this issue, we generated a transgenic mouse model with heart-specific overexpression of PP2A-PR72. Biochemical and physiological methods were used to determine contractility, Ca2+ cycling parameters, and protein phosphorylation.

Results

A 2.5-fold increase in PR72 expression resulted in moderate cardiac hypertrophy. Maximal ventricular pressure was increased in catheterized transgenic mice (TG) compared to wild-type (WT) littermates. This was accompanied by an increased shortening of sarcomere length and faster relaxation at the single-cell level in TG. In parallel with these findings, the peak amplitude of Ca2+ transients was increased, and the decay in intracellular Ca2+ levels was shortened in TG compared to WT. The changes in Ca2+ cycling in TG were also evident from an increase in the full duration and width at half maximum of Ca2+ sparks. Consistent with the contractile data, phosphorylation of phospholamban at threonine-17 was higher in TG hearts. The lower expression of the Na+/Ca2+ exchanger may also contribute to the hypercontractile state in transgenic myocardium.

Conclusion

Our results suggest that PP2A-PR72 plays an important role in regulating cardiac contractile function and Ca2+ cycling, indicating that the upregulation of PR72 in heart failure is an attempt to compensate functionally.
Development of Fe2O3/YSZ ceramic plates for cryogenic operation of resistive-protected gaseous detectors
Authors: Olano-Vegas L. , Pardo I. , Leardini S. , Morales M. , Carreira A. R. , Corral R. M. , González-Díaz D. , Tesi A. , Moleri L. , Azevedo C. D. R. , Carramate L. , Guitián F.
Published: October 2023

We present a ceramic material based on hematite (Fe2O3) and zirconia stabilized with yttria at 8% molar (YSZ), that exhibits stable electrical properties with transported charge and that can be tuned to the resistivities necessary to induce spark-quenching in gaseous detectors (ρ = 109-1012 Ω⋅cm), from room temperature down to the liquid-vapor coexistence point of nitrogen (77 K). It, thus, allows covering the operating temperatures of most immediate interest to gaseous instrumentation. The ceramics have been produced in a region of mass concentrations far from what has been usually explored in literature: optimal characteristics are achieved for Fe2O3 concentrations of 75%wt (LAr boiling temperature), 35%wt (LXe boiling temperature), and 100%wt (room temperature). The nine-orders-of-magnitude enhancement observed for the electrical conductivity of the mixed phases relative to that of pure Fe2O3 is startling, however it can be qualitatively understood based on existing literature. Plates of 4 cm × 4 cm have been manufactured and, prior to this work, operated in-detector at the LXe boiling point (165 K), demonstrating spark-free operation. Illustrative results obtained for the first time on a spark-protected amplification structure (RP-WELL) at around the LAr boiling point (90 K) are now presented, too.
Effect of electronic health records on doctor-patient relationship in Arabian gulf countries: a systematic review
Authors: Tabche Celine , Raheem Mays , Alolaqi Arwa , Rawaf Salman
Published: October 2023

Background

The electronic health record (EHR) has been widely implemented internationally as a tool to improve health and healthcare delivery. However, EHR implementation has been comparatively slow amongst hospitals in the Arabian Gulf countries. This gradual uptake may be linked to prevailing opinions amongst medical practitioners. Until now, no systematic review has been conducted to identify the impact of EHRs on doctor-patient relationships and attitudes in the Arabian Gulf countries.

Objective

To understand the impact of EHR use on patient-doctor relationships and communication in the Arabian Gulf countries.

Design

A systematic review of English language publications was performed using PRISMA chart guidelines between 1990 and 2023.

Methods

Electronic database search (Ovid MEDLINE, Global Health, HMIC, EMRIM, and PsycINFO) and reference searching restricted to the six Arabian Gulf countries only. MeSH terms and keywords related to electronic health records, doctor-patient communication, and relationship were used. Newcastle-Ottawa Scale (NOS) quality assessment was performed.

Results

18 studies fulfilled the criteria to be included in the systematic review. They were published between 1992 and 2023. Overall, a positive impact of EHR uptake was reported within the Gulf countries studied. This included improvement in the quality and performance of physicians, as well as improved accuracy in monitoring patient health. On the other hand, a notable negative impact was a general perception of physician attention shifted away from the patients themselves and towards data entry tasks (e.g., details of the patients and their education at the time of the consultation).

Conclusion

The implementation of EHR systems is beneficial for effective care delivery by doctors in Gulf countries despite some patients' perception of decreased attention. The use of EHR assists doctors with recording patient details, including medication and treatment procedures, as well as their outcomes. Based on this study, the authors conclude that widespread EHR implementation is highly recommended, yet specific training should be provided, and the subsequent effect on adoption rates by all users must be evaluated (particularly physicians). The COVID-19 Pandemic showed the great value of EHR in accessing information and consulting patients remotely.
On the intriguing subject of the low amplitudes of magnetic anomalies at the Powell Basin
Authors: Catalán M. , Negrete-Aranda R. , Martos Y. M. , Neumann F. , Santamaría A. , Fuentes K.
Published: October 2023

The Powell Basin is a small oceanic basin bounded by continental blocks that fragmented during break up of Antarctica from South America. This basin bounds the South Orkney Microcontinent to the east, the South Scotia Ridge to the north, and the Antarctic Peninsula to the west. The timing of its opening is poorly constrained due to the low amplitude of the oceanic spreading magnetic anomalies which hampers their identification and interpretation causing large uncertainties in proposed ages that range from the Late Eocene to Early Miocene. This basin has been extensively studied using a variety of geophysical methods including seismic, gravity and magnetics surveys intended to unveil the tectonic domains, the particularities of its magnetic anomalies and the understanding of the thermal regime in this area. Here, we show new magnetic and heat flow data integrated with other geophysical data from international databases (multichannel seismic data, bathymetry and free-air gravity), to analyze the thermal structure of the lithosphere of Powell Basin and the upper mantle dynamics as well as to discuss the probable causes of the abnormally small amplitudes of its magnetic anomalies. Our results show that the low magnetic anomaly amplitudes are not widespread but concentrate in the eastern and southwestern part of the basin. We propose that these small amplitudes result from the thermal dependency of magnetic rocks caused by an asthenospheric branch flow that penetrates the Powell Basin through the northern area.