bluuebunny/crossref_metadata_2025 huggingface dataset:
Graphically-Defined Model Reactions are Extensible, Accurate, and Systematically Improvable
Authors: Zhao Qiyuan , Singla Veerupaksh , Hsu Hsuan-Hao , Savoie Brett
Published: February 2025

Achieving fast and accurate reaction prediction is central to a suite of chemical applications. Nevertheless, classic approaches based on templates or simple models are typically fast but with limited scope or accuracy, while the emerging machine learning-based models are limited in their transferability due to the lack of large reaction databases. Here, we address these limitations by formalizing the model reaction concept based on fixed-depth condensed reaction graphs that are shown to achieve a cost and accuracy balance that is applicable to many problems. The model reaction concept can be utilized to provide reliable predictions of activation energies and transition state geometries for a large range of organic reactions. In addition, using an alkane pyrolysis system as a benchmarking example, we show that the accuracy of the activation energy prediction can be further improved by adding correction terms based on the empirical Br{\o}nsted-Evans-Pokanyi (BEP) relationship. These successful applications demonstrate that the model reaction can serve as a general tool to reduce the cost associated with ab initio transition state searches.
Analysis of the Current State and Innovations in Professional Development and Teacher Training in Higher Education: The Case of Slovenia
Authors: Mezgec Maja
Published: February 2025

In higher education throughout Europe and internationally, greater importance has been ascribed to the quality of university teaching in recent decades. The quality of teaching is becoming integrated into the complex process of university quality assurance and higher education teacher training is becoming increasingly important. The aim of the present article is to examine the professional development of higher education teachers in Slovenia, particularly with regard to initial entry training and continuing training for educational work. Higher education teachers are active in both research and teaching. If doctoral studies equip future academics for research work, the question arises as to where and how higher education teachers acquire knowledge and develop competences and skills for work in the educational process and how educational training is embedded in the professional development of higher education teachers in Slovenia. The analysis shows that, within the current frameworks for career progression, higher education teachers have to prioritise research work, while lower priority is given to teaching achievements from the early stage of the academic career.
C60 fullerene improves the recovery of biomechanical parameters of muscle soleus contraction in rats after chronic alcoholization
Authors: Nozdrenko D. M. , Nan W. , Matvienko T. Yu. , Bogutska K. I. , Shevchuk T. Ya. , Berest V. P. , Prylutskyy Yu. I.
Published: February 2025

Background: Recovery of biomechanical parameters of contraction of muscles damaged by alcoholic myopathy is a rather complex and long-term process. Therefore, the search for effective therapeutic means for its acceleration is an extremely urgent task in biomedicine.

Aim of work: The effect of C60 fullerene aqueous solution (C60FAS) on the dynamics of skeletal muscle contraction in rats after 9 months of chronic alcoholization and 2 months after cessation of alcohol consumption was investigated.

Materials and Methods: When analyzing the miotic response using tensometry, such biomechanical parameters as the time of reduction of the muscle force response by 50% from the initial value, the values of the contraction force and the impulse of the muscle force were evaluated.

Results: It has been shown that animals orally administered alcohol and C60FAS (daily dose of 1 mg/kg) together (scheme II) during the experiment showed an increase in muscle force response by 40–45±2% compared with the group of alcoholized animals and by 12–15±1% compared with the group of rats administered C60FAS 1 h after alcohol ingestion (scheme I). The positive effect of C60FAS administration according to scheme II and scheme I was 34±2% and 10±1%, respectively, compared with the group of alcoholized animals in the case of recording the time of reduction of the muscle force response by 50% of the initial value. After 2 months of rehabilitation, the level of minimum muscle contraction force when using C60FAS in both schemes differed by about 15±1% compared to the group of alcoholized animals, and the time of reduction of the force response by 50% was not significantly recorded. Finally, the use of C60FAS revealed a significant increase in the magnitude of the muscle force impulse: up to 86±4% (scheme I) and almost to control values — 94±2% (scheme II).

Conclusions: The obtained results indicate the prospects of using C60FAS to restore the biomechanical parameters of skeletal muscle contraction during long-term development of alcoholic myopathy.
Life forms and shoot structure of the invasive species Geranium sibiricum l. (Geraniaceae) in two local populations in Ukraine
Authors: Kalista M.S. , Kovalenko O.A.
Published: February 2025

It was found out that the life form of the alien invasive plant species Geranium sibiricum is interpreted ambiguously in various literature sources, and in the description of underground organs (shoot and root systems), the statements of different authors are often even contradictory. Eighty individuals of G. sibiricum collected in 2019–2021 during field research in two local populations: in Pyriatyn town (Poltava Oblast) and Kyiv City (Kyiv Oblast) were revised by varying the type of growth form and shoot structures using the deep concept of the caudexes diversity and their differences from other structural formations. The basic life form and model of shoot formation of G. sibiricum, which is a biennial conode taproot monocarpic with monopodial branching type, were clarified. In the connection with the pronounced polyvariety of the species life form two more types of it were described in G. sibiricum individuals: caudex taproot oligocarpic and basiphys fibrousroot oligocarpic with sympodial type of branching. The structure of elementary inflorescences of G. sibiricum was analysed, the structure of its above-ground and underground shoot system, as well as the root system, was investigated. It was identified that G. sibiricum individuals in Pyriatyn town and Kyiv City populations differ in the length of the flowering shoot, the length of the internodes, and the level of branching, and they have different types of generative shoots according to their location in space. It was found that the diversity of the architectural structure of individuals of this invasive species, associated with different growth conditions, could probably be an adaptation to the specific environmental conditions of their populations and could be valuable for studying the introduction of invasive species and determining the developmental stages at which the management of their populations will be most effective.
Environmental plasticity of short-stemmed winter bread wheat (Triticum aestivum L.) cultivars and resistance to yellow leaf blotch (Pyrenophora tritici-repentis (Died.) Drechsler) and brown (leaf) rust (Puccinia recondita f. sp. tritici Rob. et Desm.)
Authors: Yarosh A.V. , Kucherenko Ye.Yu. , Riabchun V.K. , Kuzmyshyna N.V. , Solonechna O.V.
Published: February 2025

In the context of variability of common pathogens of foliar diseases of winter bread wheat, evolvement of virulent and aggressive races, and periodic droughts, which with climate changes increasingly occur in the territory of Ukraine, prerequisites for in-depth research into adaptability of plant varieties and selection of the best gene pool for breeding arise. The paper presents results on the environmental plasticity of short-stemmed winter bread wheat cultivars, which were differentiated by resistance to yellow leaf blotch and brown (leaf) rust. New sources of high and stable group resistance to pathogenes of these diseases were identified: cv. 'Versiia odeska' (UKR) and cv. 'Mescal' (FRA). By genotypic effect (εi) and regression coefficient (Ri) for yield, the following genotypes showing the highest genetic potential for adaptability (sum of ranks = 2) to stressful conditions of cultivation in the eastern forest-steppe of Ukraine and yielding by 16% more than the check cultivar were identified among the short-stemmed cultivars under investigation: cv. 'Pokrovska' (εi = 1.92; Ri = 0.60) (UKR), cv. 'Versiia odeska' (εi = 1.21; Ri = 0.77) (UKR), cv. 'MIP Vidznaka' (εi = 1.05; Ri = 0.82) (UKR), cv. 'Mescal' (εi = 0.98; Ri = 0.65) (FRA), and cv. 'SY Wolf' (εi = 0.94; Ri = 0.69) (USA). It was found that the genotypic effect for yield ranged from -1.71 to 1.92 in the short-stemmed cultivars, and the regression coefficient - from 0.60 to 1.45, which largely affected the environmental plasticity: the sum of ranks for this parameter varied from 2 to 6. The percentage of accessions with high genotypic effects was 33.3%; the percentage of accessions with consistently stable yields was 41.7%. It was revealed that in short-stemmed winter bread wheat, resistance to brown rust and yellow leaf blotch was significantly negatively correlated with the sum of ranks of the genotypic effect and regression coefficient for yield (r = -0.65, P < 0.01 and r = - 0.58, P<0.01, respectively). The selected sources of high group resistance to Pyrenophora tritici-repentis (Died.) Drechsler) and brown (leaf) rust (Puccinia recondita f. sp. tritici Rob. et Desm., with high yield potential and stability, are valuable starting materials for the breeding of new, highly promising winter bread wheat cultivars, which will be adaptable to stressful conditions of cultivation in the eastern forest-steppe of Ukraine.
Safety Production Management During the Construction and Operation Phases of Thermal Power Enterprises
Authors: Liu Xu
Published: February 2025

In the energy industry landscape, thermal power generation stands as a critical energy supply method, and the safety of its construction and operation is paramount. Currently, all stages of the life cycle of construction projects have garnered widespread attention. Among these, the infrastructure construction and operation phases of thermal power generation enterprises pose numerous issues worthy of in-depth study in terms of safety production management. This article starts by examining safety production management during these two phases, analyzing characteristics such as management models, legal bases, and responsible entities. It explores the reasons behind these characteristics and elaborates on key management priorities, providing a comprehensive and insightful reference for safety production management in thermal power generation enterprises.
Research on the Interactive Design of Smart Home Interface for the Elderly Based on QFD and HCI
Authors: Wang Kun , Liu Xuan , Li Kexiang , Xiong Zhuang , Li Bingzhe
Published: February 2025

In an aging society, the interface design of smart home products is crucial to the quality of life of the elderly. This paper combines Quality Function Deployment (QFD) and Human-Computer Interaction (HCI) theories, taking smart washing machines as an example, to explore new paths for the interface design of smart home products for the elderly. An interdisciplinary approach is adopted to construct a design process centered on elderly users, introduce the Kano model to classify requirements, realize the mapping and sorting of requirements to design parameters, and adopt the PUGH model for comprehensive evaluation. This study provides practical and theoretical support for the interface design of smart home products for the elderly.
Ставлення вчителів до використання військово-прикладних вправ на уроках фізичної культури
Authors: Leus Stepan
Published: February 2025

Topic. Military-applied exercises have not been widely implemented in the physical education of schoolchildren. However, geopolitical changes that have taken place in Ukraine were not taken into account. Today, there is an urgent need to prepare schoolchildren for the future defense of Ukraine through military-applied exercises. Aim and Methods of the Study. The aim of the research was to explore the possibilities of using military-historical methods in the physical education of students. A total of 2,119 respondents from 21 regions of Ukraine were surveyed, including teachers of physical education, Ukrainian history, and defense studies. MS Excel was used for the mathematical processing of the results. Results of the Study and Key Conclusions. More than 70 % of teachers support the inclusion of military-applied exercises in physical education lessons, with the highest level of support among teachers of the subject Defense of Ukraine. Under wartime conditions, the relevance of such exercises remains high, and experts agree that the development of these skills should begin at an earlier age. Military-historical reconstruction received considerable attention from teachers due to its complexity and cost. However, they believe that incorporating its elements can motivate students (55,0 %), foster patriotism (78,2 %), better prepare youth for service (69,3 %), and enhance their ability to defend Ukraine (47,7 %). Overall, 71,3 % of respondents support the introduction of military-applied exercises in physical education lessons, while 55,3 % consider them particularly beneficial for students in grades 10–11. More than 80 % of interviewees highlighted the need to update the educational content of Physical Education, Defense of Ukraine, and Ukrainian History courses in accordance with the realities of modern warfare. Therefore, military-historical reconstruction has the potential to serve as an innovative method of physical and patriotic education for students, provided its implementation is optimized. However, this requires the development of a clear methodological framework.
Біоімпедансний аналіз показників компонентів складу тіла жінок 35–45 років
Authors: Rymar Olha
Published: February 2025

Topicality. Analysis of anthropometric and metabolic parameters in women aged 35–45 is highly relevant due to the increasing prevalence of metabolic disorders, cardiovascular diseases, and obesity. It is crucial to assess body composition, including levels of fat and muscle mass, visceral fat as a marker of metabolic risk, and basal metabolic rate. Studying these parameters allows for the development of effective individualized approaches to the prevention and correction of body mass-related disorders, and also promotes the formation of a healthy lifestyle. The Research Aim is to investigate bioimpedance parameters of body composition components in women aged 35–45. Material and Methods. A review of literature, bioimpedance analysis using the TANITA BC-730, and statistical analysis. Research Results.The study found that most women (60 %) had optimal body fat levels, while 22 % had elevated levels, 14 % were obese, and 4 % were underfat. Visceral adiposity was increased in 36 % of participants. Despite adequate hydration in most cases (88 %), 20 % exhibited signs of dehydration. Muscle mass was within normal limits for all participants. However, basal metabolic rate showed significant variability, with 46 % of women displaying lower than expected values. Body composition analysis revealed that 30 % had a normal body type, 28 % were overweight, and 4 % were obese.Conclusions. The study revealed that most women aged 35–45 had normal anthropometric and metabolic parameters. However, 26 % were overweight, 4 % had grade I obesity, and 36% exhibited elevated levels of visceral fat, indicating a need for lifestyle modifications.
INCLUSION OF SUSTAINABLE DEVELOPMENT CONTENT IN ENGLISH TEXTBOOKS OF SECONDARY LEVEL: AN ANALYTICAL STUDY
Authors: Kumar Sarvesh , Arora Santosh
Published: February 2025

Sustainable development is crucial to the solution of the interrelated threats of the 21st century-a triple threat of environmental, social, and economic. Learning about sustainability is important to each learner, and textbooks act as a critical source of learning for this purpose. The representations of the SD concepts in the English NCERT textbooks for Grades IX (Beehive) and X (First Flight) were explored with the objective of evaluating their appropriateness to the ESD framework. Using a qualitative content analysis approach, this study examines the textbooks of secondary level of English subject in terms of environmental, social, and economic perspectives on sustainability. Literary works, poems, and narrative prose are analysed to evaluate the implicit and explicit inclusion of SD themes like climate change, conservation, gender equality, and economic equity. The effectiveness of associated exercises and activities in promoting critical thinking and action-oriented learning is also reviewed. The findings reveal that SD themes are present but are predominantly implicit, with a greater emphasis on environmental aspects compared to social and economic dimensions. Pedagogical opportunities to connect textual content with practical sustainability issues are often underutilized. Exercises and activities encourage reflective thinking but rarely draw direct links to global challenges such as climate change or poverty alleviation.
Primer Design of Sumatran Striped Rabbit (Nesolagus netscheri Schlegel, 1880) using Primer-BLAST and AliView Program
Authors: Aurora Dhea Apriano , Novarino Wilson , Tjong Djong Hon , Dahelmi Dahelmi , Syaifullah Syaifullah , Setiawan Arum , Roesma Dewi Imelda
Published: February 2025

The Sumatran striped rabbit (Nesolagus netscheri) lacks specific primers to amplify the chytochrome oxidase 1 (CO1) gene and the chytochrome b (cytb) gene, at present. Therefore, it is important to design primers to amplify the CO1 gene and cytb gene in N. netscheri. The aim of this study is to compare the primer design methods used, namely Primer-BLAST and AliView programs, to design specific primers for the chytochrome oxidase 1 (CO1) and chytochrome b (cytb) genes in N. netscheri. This research was conducted using the descriptive method with molecular observation. In this study, CO1 gene primers, namely [(forward: 5' TGTATGATATGGGGGAGGGC 3'), (reverse: 5' TGGTCCGTCCTTATTACAGCG 3')] and cytochrome b (cytb) gene primers, namely [(forward: CCAGCTCCATCCAATATCTC, (reverse: 5' GTTAGGGTTAGAAGGTCTGC 3')] and showed that primer design using the AliView program produced specific primers in the genus Nesolagus. The conclusion of this study is that primers designed using the AliView program are more specific than those designed using Primer-BLAST.
PÍTON NO ZOOBOTÂNICO DE BRUSQUE: UM CASO CLÍNICO DE ESTOMATITE INFECTOCONTAGIOSA
Authors: Silvestre Acampa , Pedroso Karolyne Kasmirczak , Müller Gabrielle do Amaral e Silva
Published: February 2025

A estomatite é uma afecção da mucosa oral comumente causada por bactérias gram-negativas presentes na microbiota oral e de todo o trato digestivo e tem como principal sintoma a perda de apetite e hipe
Capítulo 11 - AS CONTRIBUIÇÕES DA LEITURA DIGITAL DE CRÔNICAS DE RUBEM BRAGA POR MEIO DAS FUNCIONALIDADES DA FERRAMENTA PADLET PARA O ENSINO FUNDAMENTAL II
Authors: Bittencourt Camila da Silva , Oliveira Maria Madalena Fernandes Caetano Poleto
Published: February 2025

Esta pesquisa propõe investigar e refletir sobre as contribuições da leitura digital de crônicas de Rubem Braga por meio das funcionalidades da ferramenta Padlet para o ensino fundamental II. O Padlet é uma ferramenta on-line que permite a criação de um mural ou quadro virtual dinâmico e interativo para registrar, guardar e partilhar conteúdos multimídia, funcionando como uma folha de papel, onde se pode inserir qualquer tipo de conteúdo (texto, imagens, vídeo, hiperlinks), juntamente com outras pessoas. Acredita-se que essas funcionalidades trabalhadas de maneira estratégica favorecem a prática de leitura de textos literários como as crônicas e, por conseguinte, uma melhora no processo ensino-aprendizagem. Nesse sentido, optou-se por fazer uma investigação por meio de uma pesquisa de natureza qualitativa participante. Pretende-se propor uma sequência de atividades (sequências didáticas) voltadas à leitura digital de crônicas de Rubem Braga que abordam aspectos sociais do cotidiano a partir das funcionalidades da referida ferramenta com o objetivo de incentivar a leitura, o pensamento crítico e a produção textual. As crônicas serão extraídas através do site “Portal da Crônica Brasileira”, que reúne 1011 crônicas do autor capixaba. Posteriormente, será realizada a produção e publicação de um ebook para que outros usuários possam ter acesso e utilizar os resultados da pesquisa, corroborando para que a leitura de crônicas seja mais interessante e agradável por dialogar com a realidade dos estudantes do século XXI que, inegavelmente, vivem em uma era de expansão da tecnologia digital. Além disso, outros usuários terão acesso às possibilidades de trabalhar a leitura, o pensamento crítico e a escrita a partir do gênero crônica e do autor Rubem Braga. Como aporte teórico sobre a relação da tecnologia digital como instrumento para se ensinar na escola serão usados como base os estudos de Marcuschi (2008), que retrata sobre a multiplicação dos gêneros, Moran (2012) que traz importantes considerações acerca da educação na era digital e Silva e Lima (2018) que sugerem as possibilidades da ferramenta padlet para a leitura digital.
Capítulo 05 - COMO VENHO APRENDENDO A ENSINAR ARTES VISUAIS: a experiência do Colégio Lyceu de Goiânia
Authors: Assis Henrique Lima
Published: February 2025

Esta narrativa partilha experiências singulares do processo de aprender a ensinar Artes Visuais vivido por mim, o autor. Apoiada nos princípios filosóficos e metodológicos das narrativas (Barthes, 2009; Bosi, 2003; Souza, 2006), foi tecida tramando aspectos importantes de uma experiência artística/educativa experenciada na educação básica, que também colaborou com o processo de transformação do professor que sou, ou melhor, que estou, visto que esse processo formativo e transformativo é inacabável. A narrativa aqui exposta tornou-se complexa porque acolheu, em sua tessitura, as implicações de ser reflexiva e poética, buscando a compreensão do cotidiano das aulas vividas com as/os estudantes do Ensino Médio, do Colégio de Ensino em Período Integral (CEPI) Lyceu de Goiânia, em sua multiplicidade e simultaneidade de sentidos e significados. Inspirados no Projeto de Trabalho (Hernández, 2000) denominado Expedições fotográficas: conhecendo a art déco a partir do Colégio Lyceu de Goiânia, as/os estudantes que optaram por cursar a disciplina eletiva de Arte ampliaram seus saberes e fazeres fotográficos, bem como entenderam melhor os movimentos Art Déco e Colonial que, política e estrategicamente, foram escolhidos para desenhar a escola ondem estudavam.
Capítulo 08 - VISÃO HISTÓRICA RESUMIDA SOBRE A ORIGEM DOS INDÍGENAS NO BRASIL
Authors: Silva Maria José Dias P.
Published: February 2025

Breve resumo sobre a origem dos povos indígenas no Brasil, apontando para a ocupação das Américas, deslocamentos de povos ao longo das eras, origens e descobertas antropológicas.
The use of ChatGPT in addressing Algebra anxiety and promoting confidence
Authors: Etcuban Jonathan Olores
Published: February 2025

ChatGPT was a learning revolution known as an online program for learning Algebra; it changed what we knew about the teaching medium and molded the learning platform into a more engaging way of teaching. This research determines the use of ChatGPT in addressing math anxiety and promoting the confidence of college students enrolled in algebra at a Philippine state university. Using a purposive sampling technique the descriptive correlational method was utilized by employing a three-part questionnaire to 320 selected students using purposive sampling. The gathered quantitative data were treated using frequency, mean, standard deviation, and Chi-square test of independence. The study revealed that most respondents are enrolled in the College of Arts and Sciences, aged 22 to 23, female, and full-time first-year students who agreed that ChatGPT addressed Algebra anxiety and promoted Algebra confidence, resulting in a very good score on the Algebra performance test. Also, it reveals that students' Algebra performance is significantly related to the college to which they belong and the respondents’ ages. Furthermore, the study shows that the students’ Algebra performance correlates with using ChatGPT to promote Algebra confidence. Using ChatGPT in algebra instruction has shown promising results in raising student confidence, and it suggests including ChatGPT in algebra instructional materials. The researcher suggests integrating ChatGPT into the algebra course materials to promote more diverse and practical learning settings.
AVANÇOS NA ESCOLHA DO MÉTODO DE IMAGEM CARDIOVASCULAR NA INFLAMAÇÃO E ATEROSCLEROSE
Authors:   Instituto do Coração do HCFMUSP. São Paulo, SP, Brasil, Liberato Gabriela ,   Hospital Sírio-Libanês. São Paulo, SP, Brasi, B. Sobral-Alves Juliana ,   Instituto do Coração do HCFMUSP. São Paulo, SP, Brasil,   Hospital Vila Nova Star, Rede Dor. São Paulo, SP, Brasil., M. Fuzissima Bruno ,   Instituto do Coração do HCFMUSP. São Paulo, SP, Brasil, M. Pinto Ibraim ,   Instituto Dante Pazzanese de Cardiologia. São Paulo, SP, Brasil., Vieira Marcelo ,   Instituto do Coração do HCFMUSP. São Paulo, SP, Brasil,   Hospital Albert Einstein. São Paulo, SP, Brasi, E. Rochitte Carlos ,   Instituto do Coração do HCFMUSP. São Paulo, SP, Brasil,   Hcor, Hospital do Coração. São Paulo, SP, Brasi
Published: February 2025

As doenças cardiovasculares, especialmente a doença arterial coronariana crônica (DAC), são a principal causa de mortalidade tanto globalmente quanto no Brasil. Os avanços na imagem cardíaca, envolvendo a ecocardiografia, a tomografia computadorizada (TC) e a ressonância magnética (RM), têm desempenhado um papel significativo na melhoria do diagnóstico precoce, da estratificação de risco e da compreensão de biomarcadores em aterosclerose. O ecocardiograma, um exame não invasivo, acessível e de baixo custo, é tradicionalmente usado para avaliar a função cardíaca, mas também desempenha um papel crucial na detecção e acompanhamento das complicações da aterosclerose e da doença arterial coronariana. A TC se destaca pela resolução temporal e espacial, fornecendo uma avaliação precisa das artérias coronárias, enquanto a RM oferece excelente diferenciação tecidual, mas ainda é limitada para a avaliação coronariana. A tomografia do coração já é validada e incorporada em recomendações internacionais quanto à avaliação de aterosclerose calcificada pelo escore de cálcio coronariano e à avaliação do grau de estenose pela angiotomografia de coronárias (ATCC). No entanto, eventos de síndrome coronariana aguda frequentemente estão relacionados a placas não obstrutivas, e a ATCC também é capaz de analisar características de alto risco de placas ateroscleróticas, oferecendo uma alternativa não invasiva aos procedimentos de imagem intracoronária, como IVUS e FFR. As novas fronteiras de avaliação em aterosclerose são a estimativa de volume de ateroma (carga de placa) e a avaliação do tecido adiposo epicárdico (TAE), sendo o Índice de Atenuação da Gordura (FAI) um dos métodos propostos para sua quantificação. No entanto, a padronização e aplicabilidade desses métodos somente serão viáveis com a integração da inteligência artificial (IA) na análise e pós-processamento de imagens. Esta revisão destaca o cenário em evolução da imagem cardiovascular e seu potencial para guiar a prevenção e o tratamento da doença arterial coronariana e da aterosclerose
Co-redenção Mariana
Authors: Terra João E. Martins
Published: February 2025

A Mariologia tem tomado inegavelmente um notável incremento nos dois últimos séculos. Nós vivemos numa era mariana. Em nenhuma época os estudos mariológicos polarizaram tão intensamente as atenções dos teólogos e dos fiéis em geral como em nossos dias. As teologias patrística e escolástica consideraram de preferência os privilégios pessoais e a excelsa dignidade de Maria Santíssima: Maternidade divina, Conceição imaculada, Assunção corpórea aos céus... Hoje as considerações dos teólogos se voltam para as operações e atribuições de Maria em relação aos homens...
Liquid Metal Embrittlement Elimination in RSW of Galvannealed AHSS DP980
Authors:   American Welding Society, ABDELMOTAGALY, ABDELRAHMAN , SCHNEIDERMAN BENJAMIN , YU ZHENZHEN , HU JIANXUN , CHIHPIN CHUANG ANDREW
Published: February 2025

Liquid metal embrittlement (LME) is a longstanding problem for resistance spot welding (RSW) of Zn-coated automotive sheet steels, especially third generation advanced high-strength steels (AHSSs). This work designed a multi-principal element alloy (MPEA), considered a high entropy alloy (HEA), that preferentially absorbs Zn during RSW and forms a single solid solution phase. The MPEA composition was designed using a highthroughput multi-physics-based analysis, which down-selected the FeMnNiCoZn system as favorable to present a single face-centered cubic (FCC) phase over a broad dilution composition space with the substrate. Comparing the welds made with MPEA foils to control welds without the MPEA, optical microscopy revealed no visible LME cracks in MPEA welds, whereas Zn-lined cracks with a length of 5–100 μm populated the control welds. Energydispersive spectroscopy demonstrated the MPEAlimited Zn penetration distance into the AHSS grain boundaries to less than 10 μm. Kinetic simulations also predicted the MPEA would retain Zn as a solid solution and limit its penetration into the AHSS substrate. Site-specific synchrotron diffraction confirmed a single FCC phase in the MPEA and an unaffected ferrite/martensite microstructure in the adjacent DP980 AHSS substrate. Furthermore, tensile-shear tests showed average improvements of 21% in peak load and 80% in fracture energy in welds employing MPEA foils when welded with the same current and schedule.
Assessment of iron profile in dialysis patients receiving erythropoietin in bowen university teaching hospital, Ogbomoso, Nigeria
Authors: Kikelomo Olayemi Oyeleke  , Etuvie Favour Akomolafe  , Busayo Kayode Akomolafe  , Olawale Sunday Animasaun  , Sulaiman A Nassar
Published: February 2025

Background: Chronic kidney disease (CKD). Also referred to as chronic kidney failure, is the existence of renal impairment or an estimated glomerular filtration rate (eGFR) that is less than 60 mL/min/1.73 m², sustained for three months. At this time, CKD prevalence has increasingly become a global public health concern leading to failure of kidney, cardiovascular disease, and early mortality. The earliest complication observed among CKD patients is anemia, which is largely a result of relatively insufficient erythropoietin (EPO) production that results from compromised renal function. The utilization of iron indices markers is essential for Evaluating iron status is essential in managing both iron deficiency and anemia in individuals with CKD Objective: This study assessed the iron profile among renal dialysis patients attending Bowen University Teaching Hospital (BUTH) Ogbomoso, Nigeria.

Materials and methods: A prospective analytical case-control study and a hospital-based study conducted from March 2024 to October 2024 in BUTH Ogbomoso, Oyo State, Nigeria in this study, 60 older CKD patients in various stages on dialysis attending the nephrology dialysis center of Bowen University Teaching Hospitals in Ogbomoso Oyo state, Nigeria were enrolled into the study. Blood samples were collected from each participant into plain bottles, samples were used for iron indices, the Colorimetry method was used for serum total iron, transferrin, total iron binding capacity (TIBC), and ELISA technique was used for ferritin, while Transferrin saturation (Tsat) was calculated.

Results: Dialysis patients on rHuEPO had significantly higher serum ferritin, Transferrin, TIBC, Tsat, and Total iron when compared with non-rHuEPO (p<0.05), with mean±SD of 259.00±17.76 ng/ml, 219.57±15.74mg/dl, 300.82±21.96µmol/l, 37.00±5.30%, and 108.80±13.8 respectively. non-rHuEPO subjects had significantly low serum ferritin, Transferrin, TIBC, Tsat, and Total iron when compared with rHuEPO (p<0.05), with mean±SD of 207.63±25.68 ng/ml, 197.70±13.85mg/dl, 278.75±19.53µmol/l, 23.47±2.30%, and 64.80±5.45µmol/l respectively. Total iron correlated positively with % TSAT while Transferrin and Ferritin correlated positively with TIBC (p<0.05).

Conclusions: The study revealed a significantly increased serum level of Total iron, transferrin saturation, TIBC, and Ferritin in subjects treated with rHuEPO compared to non-RHuEPO patients.
Green Accounting Disclosure and Its Effect on Financial Performance of Mining Company
Authors: Destiana Rizka , Simorangkir Bella Rizky Anggraini
Published: February 2025

This research examines the influence of environmental costs, environmental performance, and environmental disclosure on financial performance in the mining industry. The population in this study comprises all mining companies listed on the Indonesia Stock Exchange during the period 2018-2022. By using a purposive sampling method, 15 companies meet the criteria with a total of 175 data sets. Quantitative data analysis was employed in this study using time-series data. Data collection method utilized in this research was a documentation method. The analytical tool in this study is the multiple regression analysis. In this study, data is processed by using the SPSS program. The primary contribution of this research is to underscore the importance of effective environmental management within the context of the mining industry. The research findings indicate that environmental costs have a negative influence on financial performance, while environmental performance and environmental disclosure have a positive influence on financial performance.
Supply Chain Management Efficiency Measurement Using Value Stream Mapping Method to Reduce Production Waste PT Tirta Investama
Authors: Permata Nia Sastra , Suroso Muhammad Suryo Panotogomo Abi
Published: February 2025

PT Tirta Investama is a prominent Indonesian enterprise specialising in mineral water under the Aqua brand. This study aims to ascertain the nature of its waste using Value Stream Mapping methodology to assess supply chain management. A comparison of the current and future state maps shows how the Value Stream Mapping (VSM) method for measuring Supply Chain Management (SCM) has enhanced efficiency at PT Tirta Investama. The State Map showed that VA accounted for 40% of process time, and NVA accounted for 3,780 seconds. 60% of the process.By contrast, the Future State Map demonstrates a big increase in value-added activities (VA), which now account for 75% of total process time. Non-value-added activities (NVA) have dropped significantly to 25%.
An Evaluation of Supplier Selection for Pneumatic System Components in Maintenance Management Utilizing the Analytical Hierarchy Process in a Paper Packaging Manufacturing
Authors: Ramadhania Sherin , Suroso Muhammad Suryo Panotogomo Abi , Permata Nia Sastra
Published: February 2025

To ensure the continuity of the production process, it is essential for the company to focus on maintenance management, particularly in selecting high-quality pneumatic system components with a long lifespan. This study aims to determine the criteria and weights for choosing suppliers of these components in a paper packaging manufacturing. The supplier alternatives evaluated are PT. SMCAI, PT. FI, and PT. RMW, using the Analytical Hierarchy Process (AHP). The analysis of the four criteria reveals the following weights: cost (0.46), quality (0.23), service (0.16), and delivery (0.15). Based on these evaluations, PT. SMCAI ranks highest with a weight of 0.41, followed by PT. FI at 0.40, and PT. RMW with the lowest weight of 0.19. These results guide the company in selecting the most suitable supplier to maintain smooth production operations.
Can Organizational Culture Moderate the Relationship between Motivation and Auditor Performance in Public Accounting Firms in Indonesia?
Authors: Jannah Izzatul
Published: February 2025

A good quality audit is certainly the result of a good audit performance. Therefore, it is important to know the factors that influence auditor performance. This research examines whether auditor motivation can affect their audit performance and whether organizational culture can moderate auditor motivation toward their audit performance. This research uses a quantitative method with data sources in the form of questionnaire results from 196 auditors of Public Accounting Firms in Indonesia. The data in this research were processed using the PLS-SEM model with the help of SmartPLS 4 software. The research's results indicate that motivation significantly positively affects auditor performance, and organizational culture can moderate the relationship between motivation and auditor performance.
Prediction of Financial Distress in Companies on The Indonesian Stock Exchange
Authors: Sinarti Sinarti , Nurfitriadi Ayu
Published: February 2025

This research aims to determine the potential profit and cash flow by using the Altman Z-Score prediction model in predicting financial distress in manufacturing companies listed on the Indonesia Stock Exchange. Using the purposive sampling method, 98 manufacturing companies were obtained that were listed on the Indonesia Stock Exchange in the 2015-2019 period. The results of research on the sample show that profits and cash flow using the Altman Z-Score prediction model can predict financial distress in manufacturing companies listed on the Indonesia Stock Exchange in the 2015-2019 period.
The Relationship Between Morphology, Morphogenesis and Morphotectonics Potential for Flood Disasters in the Karanggayam Area, Kebumen Regency, Indonesia
Authors: Retongga Nofrohu , Razi Muhammad Haikal
Published: February 2025

The Regional Disaster Management Agency (BPBD) of Kebumen Regency recorded that from 2011 to 2020 there were 1,335 disaster events, 154 (11.5%) of which were flood disasters. There were eight flood disasters in Karanggayam District were 8 incidents. This research method consists of four stages: literature study, field observation and mapping, analysis of morphology, morphogenesis, and morphotectonics, and analysis of the relationship between morphology, morphogenesis, morphotectonics, and flood potential. The potential for flood disasters is related to the morphological aspects, morphogenesis, and morphotectonics as controlling factors for flood disasters in the research area. Based on the potential for flood disasters in the research area, it is necessary to carry out non-structural mitigation in the research area. Appropriate nonstructural mitigation of flood disasters based on field facts, such as installing an early warning system for flood disasters, having evacuation routes and signs pointing to evacuation routes, socializing flood disasters, and installing warning boards in areas prone to flood disasters to minimize the risk of flood disasters in the Karanggayam area.
Web-Based Village CCTV Information System to Support Smart City in Yogyakarta
Authors: Prabowo Hanang , Wahyuningrum Dwi , Dewi Alfiani Oktavia , Apriyanti Dessy , Srinarbito Adhiyatma
Published: February 2025

Smart cities and safe cities were modern city concepts based on information technology that had been implemented in many major cities in the world. The smart city includes information and communication technology-based city development with good infrastructure integration. One example of smart city implementation was the installation of Village CCTV in Yogyakarta City. For optimal CCTV operation, an integration system between various parties was required. In that context, the Website was used as a management tool that combined various aspects. This Website was developed using PHP MySQL as a database, JavaScript and PHP programming languages for logic and functionality, HTML as a website structure, and display design using Bootstrap. This research used qualitative methods and produced a Village CCTV Website, which had the main objective of providing information about Village CCTV efficiently and effectively in managing CCTV management. Users could quickly and accurately access information related to CCTV Village. Thus, this Website became an important tool in improving security, comfort, and surveillance in the village.
A Holographic Dual Explanation of Fractal Inflation and Dark Matter
Authors: zhou changzheng , zhou ZIQING
Published: February 2025

Based on Fractal Holographic Emergent String Theory (FHEST), this studyproposes, for the first time, a unified model of inflation and dark matter within theframework of fractal spacetime. Through fractal AdS/CFT duality, the slow-rollparameters of the inflaton field are modulated by the fractal dimension dH, withcorrections that can explain the anomalies of the low-multipole moments in theCMB power spectrum. The mass spectrum of bound states of fractal D-branes alsoaligns with dark matter observations. Numerical fits indicate that, when the fractalparameter dH ∈ [1.2, 1.6], the theoretical predictions are consistent with Lyman-αforest data and the mass distribution of the Milky Way’s halo. Further predictedobservables, such as the fractal gravitational wave spectrum and jet anisotropicsignals, provide experimental pathways for verification.
Temporal Nonlocality: A Reexamination of Causality and Time Symmetry
Authors: zhou changzheng , zhou ZIQING
Published: February 2025

Temporal nonlocality is a novel and promising concept that offers new perspectives onfundamental problems in quantum field theory, quantum gravity, and cosmology. Tradi?tional quantum field theory typically assumes locality, meaning that the evolution of afield depends solely on the state at the current spacetime point. However, introducingtemporal nonlocality extends this framework, allowing the evolution of fields to dependnot only on the present moment but also on the past and future. This nonlocalitychallenges the traditional definition of classical causality and provides new physical andphilosophical interpretations of time symmetry. In certain physical phenomena, such asquantum gravity, early-universe dynamics in cosmology, memory effects in nonequilib?rium quantum systems, and delayed-choice experiments, temporal nonlocality may beindispensable.This paper explores the specific applications of temporal nonlocality in quantum fieldtheory, particularly implications for causality and time symmetry. We argue that tem?poral nonlocality is not merely an extension of the traditional physical framework buta profound reexamination of the essence of time and the foundations of causality. Byintroducing a framework for temporal nonlocality, we redefine causality and offer a newphysical realization of time symmetry. work will focus on further refining the temporalnonlocality framework, incorporating additional physical constraints, and exploring itsapplications to other problems, such higher-dimensional compactifications.—Temporal nonlocality is a cutting-edge concept in physics that challenges fundamentalassumptions about causality and time symmetry in traditional physics. In classical andconventional quantum field theory,ality is generally assumed to be unidirectional: thepast determines the present and future, while the future cannot influence the past. How?ever, as research into quantum gravity and cosmology deepens, this traditional view hasbeen. Temporallocality introduces a new form of causal correlation, allowing interactionsbetween the past, present, and future that are no longer confined to the unidirectionalarrow of time.The primary objective of this study is to explore the specific applications of temporalnonlocality in quantum field theory and analyze its philosophical implications for causalityand time symmetry. Our contributions include:11. Proposing a mathematical framework for temporal nonlocality and applying it tospecific physical phenomena;2. Redefining causality in light of Wheeler-Feynman absorber theory;3. Investigating the applications of temporal nonlocality in delayed-choice experi?ments, quantum gravity, and cosmology, while providing new theoretical interpre?tations.
Multilevel Explanation of Time Travel and the Grandfather Paradox: The Relationship Between Dynamically Rigid Fractal Spacetime Manifolds and Wormholes
Authors: zhou changzheng , zhou ZIQING
Published: February 2025

his paper explores the feasibility of time travel within the framework of worm?holes and its resolution of the grandfather paradox, based on the Dynamically RigidFractal Spacetime Manifold (DR-FSTM) theory, combined with quantum gravityand multiverse models. By introducing fractal geometry and non-equilibrium space?time topology analysis, the essential nature of wormholes as inter-level spacetimeconnectors is demonstrated. The study reveals that the behavior of time travelersis constrained by the fractal hierarchical structure, with their causal influence lim?ited to newly generated spacetime branches, thereby mathematically circumventingclassical paradoxes. Numerical simulations further support the stability conditionsof multilevel spacetime networks.
The Hijacker's Guide to biological systems: Manipulation by self‐defecting or foreign agents
Authors: Shmeleva Evghenia , Levin Michael
Published: February 2025

Biological systems employ hierarchical regulatory networks to maintain structure and function at multiple scales, from molecules to whole organisms. This manuscript draws on evidence from various fields such as immunology, developmental biology, neuroscience and evolutionary ecology to examine how foreign agents (for instance, pathogens, parasites, trophoblasts) and self defecting agents (such as cancer cells) override these networks and exploit the host’s plasticity and regulatory flexibility, reshaping system morphology, function and behaviour. By breaching physical and informational barriers, mimicking host signals, and altering immune defences, intruders take advantage of multiscale information processing, propagating their influence across levels, from local bioelectric states to higher-order endocrine and neural circuits. Through these mechanisms, intruders disrupt homeostatic setpoints, creating periods of heightened plasticity that enable system reprogramming resulting in redirection of metabolic flows and overriding of neural, immune and endocrine signalling. These manipulation strategies rely on conserved mechanisms, transforming stable structures into flexible substrates for rearrangement, remodelling host tissues and creating niches that favour their survival. Understanding these routes of exploitation clarifies core biological principles of self-organisation and identity maintenance. Mapping how intruders induce plasticity and modify host form and function informs therapeutic strategies aimed at restoring normal tissue states, while also opening potential new paths for regenerative medicine and tissue engineering.