bluuebunny/crossref_metadata_2025 huggingface dataset:
Radiotherapy-related insufficiency fractures and bone mineral density: what is the connection?
Authors: Chatzimavridou-Grigoriadou Victoria , Barraclough Lisa H , Kochhar Rohit , Buckley Lucy , Alam Nooreen , Higham Claire E
Published: April 2023

Background

Radiotherapy-related insufficiency fractures (RRIFs) represent a common, burdensome consequence of pelvic radiotherapy. Their underlying mechanisms remain unclear, and data on the effect of osteoporosis are contradictory, with limited studies assessing bone mineral density (BMD) by dual-energy x-ray absorptiometry (DXA).

Methods

BMD by DXA (Hologic) scan and fracture risk following pelvic RRIF were retrospectively assessed in 39 patients (median age 68 years) at a tertiary cancer centre. Patient characteristics and treatment history are presented narratively; correlations were explored using univariate regression analyses.

Results

Additional cancer treatments included chemotherapy (n = 31), surgery (n = 20) and brachytherapy (n = 19). Median interval between initiation of radiotherapy and RRIF was 11 (7.5–20.8) and that between RRIF and DXA 3 was (1–6) months. Three patients had normal BMD, 16 had osteopenia and 16 osteoporosis, following World Health Organization classification. Four patients were <40 years at the time of DXA (all Z-scores > –2). Median 10-year risk for hip and major osteoporotic fracture was 3.1% (1.5–5.7) and 11.5% (7.1–13.8), respectively. Only 33.3% of patients had high fracture risk (hip fracture >4% and/or major osteoporotic >20%), and 31% fell above the intervention threshold per National Osteoporosis Guidelines Group (NOGG) guidance (2017). Higher BMD was predicted by lower pelvic radiotherapy dose (only in L3 and L4), concomitant chemotherapy and higher body mass index.

Conclusion

At the time of RRIF, most patients did not have osteoporosis, some had normal BMD and overall had low fracture risk. Whilst low BMD is a probable risk factor, it is unlikely to be the main mechanism underlying RRIFs, and further studies are required to understand the predictive value of BMD.
Cultures in periprosthetic joint infections, the imperfect gold standard?
Authors: Wouthuyzen-Bakker Marjan
Published: April 2023

Culture-negative periprosthetic joint infections (PJI) are commonly described in the literature.

By implementing a routine diagnostic workup and by optimizing tissue sampling and processing, the culture-negative rate can easily be reduced.

When faced with a culture-negative PJI, several serological and molecular techniques are available that may aid in finding the causative microorganism. Clinical clues may guide the treating physician towards more atypical and rare microorganisms.

A multidisciplinary team consisting of orthopaedic surgeons, microbiologists and infectious disease specialist are warranted in tailoring diagnostic testing and deciding on the surgical and antibiotic treatment approach.
Management of hypertension during lenvatinib for advanced thyroid cancer: a suggested diagnostic and therapeutic algorithm
Authors: Colombo Carla , Ceruti Daniele , De Leo Simone , Bilo Grzegorz , Trevisan Matteo , Giancola Noemi , Moneta Claudia , Parati Gianfranco , Persani Luca , Fugazzola Laura
Published: April 2023

Background

Hypertension (HTN) is the most frequent adverse event during treatment with lenvatinib (LEN), but data on its best management are limited.

Aim

The objective of this study was to assess incidence, features and best management of LEN-related HTN in a consecutive single tertiary-care centre cohort.

Methods

Twenty-nine patients were followed up for a mean time of 29.8 months (6–77 months).

Results

After a mean follow-up of 6.8 months, HTN was recorded in 76% of cases, as a de novo occurrence in half of them. HTN significantly correlated with LEN dose and was of grade 1, grade 2 and grade 3 in 5%, 50% and 45% of patients, respectively. The majority (77%) of patients with HTN developed proteinuria. There was no correlation between HTN and proteinuria or clinical features or best morphological response or any other adverse event (AE), with the exception of diarrhoea. Patients with or without pre-existing HTN or any other cardiovascular disease had a similar incidence of HTN during LEN, thus excluding the impact of this potential predisposing factor. After evaluation by a dedicated cardiologist, medical treatment was introduced in 21/22 patients (polytherapy in 20 of them). The most frequently used drugs were calcium channel blockers (CCBs) due to their effect on vasodilation. In case of poor control, CCBs were associated with one or more anti-hypertensive drug.

Conclusion

HTN is a frequent and early AE in patients on LEN treatment. We suggest a diagnostic and therapeutic algorithm to be applied in clinical practice to allow efficient HTN control and improve patient compliance, reducing LEN discontinuation.
Escape into Creativity: Thoughts on the Margins of a New Work about Vasyl Stefanyk
Authors: Solovka Liubov , Zhernokleiev Oleh
Published: April 2023

Reviews - Velykochyi, V., Monolatii, I., & Derkachova, O. (2022). (Un)Expected Stefanyk. Brustury: Discursus.
Iconic-Conventional Myth Synergy
Authors: Soletskyi Oleksandr
Published: April 2023

The article dwells on the problem of the iconic-conventional synergy of a myth. The myth is seen as a concept with a multifunctional status, blurred by identification attempts. Conceptual usage emphasizes its overlapping features that sport multifaceted practical typicality. As a system a myth embodies a worldview, a metaphysical form of a specifically structured narrative. Mythological consciousness includes specifically formed links between objects and phenomena, actions and cycles, all forming a system of iconic-conventional correlations. In this co-action the semantic core of a myth as a discourse is concentrated, its "symbolic matrix" is revealed, and the cognitive orientation and axiology are stated.
The Terror-Famine Trauma Through the Narrative of Novella "Holodomor" by Yevhen Hutsalo
Authors: Maftyn Natalia
Published: April 2023

One of the tasks of modern humanities, in particular Ukrainian one, is textualization of trauma as a memory that comes to life in “narratives of national identity”, since all the traumatic experience of previous generations, reflected on the mental map of Ukrainians, still remains not fully textualized, the whole situation is exacerbated by a new genocide, unleashed by Muscovy (Russia) against Ukraine. This article is devoted to the analysis of the novella “Holodomor” by Yevhen Hutsalo as a narrative of the collective trauma of the Holodomor, a terrible crime of the Moscow-Bolshevik dictatorship. The "trauma studies" methodology helps to research the narrative strategy, temporal-spacial modeling, ideological and literary sense of macro- and micro-images.

The work of Ye. Hutsalo was not written not by a direct eyewitness, yet it shows to way future generations inherit traumatic experience. The story's narrative focuses on the adherence to the historical and literary truths regarding the terrible "experiment" of the Moscow executioners and it is emphasized at the chronotope modeling level: " "tightness" of space horizontally - openness vertically; an exit from this locus of suffering is only through the grave. The author depicts the continent of the painful death of Ukrainian peasants, their struggle for life and for the salvation of their souls, the loss (or presence) of faith in the moral values that have been structuring their lives (the theocentric vertical) and all of that becomes a target of ruthless Moscow authorities who eagerly destroy everything, using food as a weapon.
Transitive Phenomena in the Grammatical System of the Language
Authors: Scherbii Natalia
Published: April 2023

The article deals with the complex issue of transitivity in the parts of the language system, their morphological and syntactic characteristics, and functional variability. It describes the preconditions for the conversion transition, and in particular the peculiar verbal character of the Ukrainian language. The article also characterizes certain typological variants of conversion, in particular, among the so-called hybrid parts of speech – adjectives, infinitives, verb-turned nouns, the grammatical properties of which border on several parts of the language. The hybrid parts of language reveal syncretism at the morphological and semantic-syntactic levels. Transitive phenomena in the parts of speech also include exclamations, in particular verbal sound-imitations which are subject to transformation into an onomatopoeic verb. The article drives to conclusion that transitive phenomena in language testify to profound internal changes in both the semantic structure and the form of the word, and consequently denote the development and changes in the language.

Practical material is taken from the national corpora of the Ukrainian and Polish languages. Using examples from modern fiction and non-fiction, we have held a study of the phenomena of interaction and conversion responsible for semantic changes in words and their structural and grammatical peculiarities.
Semantic Potential of Representatives of Doubt in Expressing Irreal States
Authors: Magas Nataliya
Published: April 2023

The research examines ways of expressing doubt as one of the communicative acts in correlation with the opposition of reality and irreality in the Ukrainian language. Nowadays the research of doubt and its representatives takes a peripheral place in works on modality, most often being observed in comparative works, regardless of the fact that the integral means of its representation are at the same time indicators of irreality at the lexical, syntactic and pragmatic levels. This is primarily explained by the semantic diffuseness and synsematicity of the expression of doubt in the Ukrainian language, which affects the difficulty of typologizing its representatives in the structure of the semantic category of irreality. Doubt as a syncretic emotional and evidential modus component, on the one hand, is an intellectual search impulse, that leads to the subject's verification of a certain extralinguistic situation depending on its correspondence to the real or irreal, which allows it to be considered in the plane of evidential semantics; on the other hand, the extensive ways of representing doubt and their aspectual characteristics point out its potential in expressing other irreal meanings in specific cases.
Zastosowanie wirtualnej rzeczywistości w leczeniu ran oparzeniowych
Authors: Spyrka Kinga , Brela Jakub , Bańkowska Karolina
Published: April 2023

Odczuwanie silnego bólu wśród pacjentów oparzonych w trakcie codziennej zmiany opatrunków stanowi powszechny problem, który jest minimalizowany za pomocą środków farmakologicznych. Rzeczywistość wirtualna może być wykorzystywana do odwracania uwagi pacjentów i zmniejszania bólu. W pracy omówiono wpływ wirtualnej rzeczywistości, jako dodatkowego narzędzia i zarazem środka niefarmakologicznego w występującym ostrym bólu u pacjentów oparzonych.
Rola aplikacji mobilnych w branży medycznej
Authors: Spyrka Kinga , Brela Jakub , Bańkowska Karolina
Published: April 2023

Streszczenie: Istnieje wiele aplikacji do monitorowania stanu zdrowia osób chorych przewlekle, które są pomocne w terapii cukrzycy, chorób serca czy otyłości. Wpływ technologii na zdrowie pacjentów jest coraz większy ze względu na nacisk w stosowaniu samokontroli i monitorowania swojego stanu zdrowia. Stosowanie aplikacji wpływa na jakość leczenia, świadomość choroby oraz stałą interakcje między pacjentem a personelem medycznym. Technologia cyfrowa stała się szczególnie ważna w dobie globalnej pandemii wirusa SARS-CoV-2. W niniejszej pracy omówiono rolę aplikacji mobilnej, jako narzędzia do szkoleń medycznych, nauki, diagnostyki medycznej oraz mobilnej komunikacji.
Neuroosteoartropatia Charcota – trudności w klasyfikacji stadium choroby i różnicowaniu problemów degradacji stawów stopy
Authors: Szkiler Elżbieta , Bitenc-Jasiejko Aleksandra , Mirosz Anna , Marglewska Monika , Kucharzewski Marek
Published: April 2023

Neuroartropatia Charcota (CN) dotyka często pacjentów z cukrzycą ze współistniejącą neuropatią obwodową. Jest to szczególny typ zespołu stopy cukrzycowej, zwany stopą cukrzycową neuropatyczną. Charakteryzuje się znaczną i postępującą destrukcją stawów i kości. Ze względu na fakt, że pierwsze symptomy to niespecyficzny ból (często brak bólu) czy zaburzenia funkcjonalności stopy (najczęściej w obrębie śródstopia), CN jest nadal zbyt późno wykrywana. Z kolei wczesna diagnoza, prawidłowe leczenie zachowawcze polegające na ustabilizowaniu i odciążeniu (a w zaawansowanych stanach unieruchomieniu i bezwzględnym odciążeniu) mogą uchronić przed znaczną degradacją stopy, a nawet amputacją. Jak najszybsze wdrożenie leczenia pozwala tym samym na uniknięcie niepełnosprawności pacjenta, gdyż znaczna degradacja stawów może również prowadzić do poważnych problemów w lokomocji.
Medycyna Beduińska
Authors: Spyrka Kinga
Published: April 2023

Medycyna Beduińska kształtowała się przez stulecia, będąc pod wpływem wielu kultur i cywilizacji. Beduińska tradycyjna medycyna ludowa opiera się na przekonaniu, że wszystko, co dzieje się z człowiekiem, zarówno dobre, jak i złe, stanowi wolę Allaha. Według Beduina tak zdrowie, jak choroba są uwarunkowane od Allaha, z pomocą naturalnych i nadprzyrodzonych mocy stworzonych przez niego. W pracy omówiono współczesną medycynę beduińską, wierzenia, stosunek do lekarzy i zachodniej medycyny, opiekę zdrowotną oraz leczenie ran i chorób przez Beduinów.
Impact of immunotherapy on wound healing in patients with melanoma
Authors: Michalčová Simona , Gaweł Władysław , Paciorek Martin
Published: April 2023

Czerniak stanowi prawie 2% wszystkich diagnoz nowotworowych i jest jednym z pięciu najczęściej stawianych diagnoz nowotworowych. Zachorowalność na czerniaka wzrasta w krajach, gdzie występuje jasna karnacja, osiągając w ciągu ostatnich 50 lat nawet 320% w samych Stanach Zjednoczonych. Chociaż podstawą leczenia czerniaka nadal pozostaje zabieg chirurgiczny, coraz więcej pacjentów poddawanych jest immunoterapii, która znacznie zmniejsza wskaźnik śmiertelności. Do najczęściej stosowanych leków należą inhibitory BRAF/MEK, które są u prawie 50% pacjentów chorujących na czerniaka, natomiast inhibitory punktów kontrolnych są stosowane w celu przywrócenia równowagi immunologicznej dezaktywowanej przez promieniowanie UV. Oba te szlaki uczestniczą również w procesie gojenia się ran, dlatego niniejsze opracowanie przeglądowe skupia się na wpływie zastosowania tego typu leczenia na proces gojenia ran u pacjentów z czerniakiem.
Acute lymphoblastic leukemia in pediatric epigenetic approach
Authors: Pat Yeh Jose Ignacio , Poot Chable Pedro Emmanuel , Guzman Félix Abner Ismael , Sandoval Jurado Luis , Rojano-Mejía David , María Valeria Jiménez Báez
Published: April 2023

Introduction and objectives: Acute lymphoblastic leukemia (ALL) in pediatric patients is an issue that affects the quality of life of the patient and his family, so it is urgent to know the physiology, presentation, and functionality of the cell population that allows determining the more effective treatments. The objective is to review the evidence derived from cohort studies and clinical trials on ALL in pediatric patients. Method: A retrospective study carried out based on the search for cohort studies and clinical trials in the last 10 years in MEDLINE, EMBASE, and Cochrane Controlled Trials Register whose keywords [Acute and Lymphoblastic Leukemia], [epigenetical], [Drug Therapy], [Pediatric]. Results: 87 articles were found based on titles and abstracts, of which 16 focus on the age group and criteria of interest. Of the 10% of the known etiology, genetic alterations are more important. However, there are epigenetic modifications that are important for leukemia to occur, such as DNA methylation, histone modification, and regulation by non-coding RNAs. Discussion/conclusions: Acute lymphoblastic leukemia in a heterogeneous pathology and the study of its molecular biology is very useful to identify therapeutic targets and have greater effectiveness in treatment and increase disease-free survival with a longer-term than the current one. In each proposed treatment scheme, it is sought that there be greater effectiveness and less toxicity as in the AIEOP-BFM ALL or IDA-FLAG schemes.
Unilateral sternal muscle in an adult melanodermic cadaver
Authors: Aragão José Aderval , Felipe dos Santos Isaias , Leão e Silva Willian Moreira , Sant’Anna Aragão Iapunira Catarina , Sant’Anna Aragão Felipe Matheus , Andrade Pimentel João Victor , Ribeiro Guerra Danilo , Prado Reis Francisco
Published: April 2023

The sternal muscle, also known as sternalis, rectussternal, parasternal or japonicus is a curious case of anatomical variation of the anterior chest wall. During a routine dissection, a muscle mass related to the sternum was found in the anterior wall of the right hemithorax in a melanodermic female cadaver. The literature, its incidence is mentioned to vary from 3.1 to 23.5%, and little is known about its function with divergences regarding its origin, insertion, innervation and vascularization. Clinically, some mastologists report that this finding is often confused with a tumor, making it difficult to distinguish between normal structures or lesions that symbolize cancer.
Marine flatworm Acanthozoon sp.-associated bacteria with antibiotic property from the Java Sea
Authors: Sabdono A. , Wijayanti D. P. , Subagiyo S.
Published: April 2023

Neglected invertebrates, marine flatworms, have attracted global research interest due to their biological and chemical potential properties. The marine flatworms (Turbellaria), Phylum Platyhelminthes, belong to the Polycladida group. There are about 3000 species of free-living flatworms that make a living by hunting and eating other animals. A marine flatworm Acanthozoon sp. was used in this study due to its abundant presence in the site location. Staphylococcus epidermidis is an opportunistic pathogenic bacterium that was previously considered a harmless skin disease bacterium. This species is now considered to be in the first rank among the causative agents of nosocomial infection, specifically in the form of infections of the urinary tract, respiratory tract, and surgical site wounds. The aims of this study were to explore the biological diversity of marine flatworm-associated bacteria with antipathogenic properties and to detect the presence of polyketide synthase (PKS) and nonribosomal peptide synthetase NRPS gene clusters through a molecular approach. Recent studies have shown that S. epidermidis undergoes functional changes in the pro-inflammatory peptide family so that it has functions in immune evasion and biofilm development. Therefore, the search for new antimicrobial compounds is urgently needed due to the limited choice of antibiotic use. In the preliminary screening by overlay test, 7 out of 17 (41.2%) isolates showed antibacterial activities. These isolates were reselected and their activity confirmed by using plug agar and disk-diffusion methods. The FA02, FA03, FA05, FA07, FA13, FA16, and FA17 isolates demonstrated their inhibitory activities consistently against the causative agent of nosocomial infection S. epidermidis. Based on the morphological and 16S rRNA partial sequencing analysis, these isolates were closely related to the genus Virgibacillus, Brevibacterium, Alcanivorax, and Vibrio. None of these seven antibacterial strains possesses PKS-I and PKS-II, except NRPS genes for Virgibacillus salarius strain FA02, V. salarius strain FA16, and V. salarius strain FA17. The results of this study showed that bacteria associated with marine flatworms have future potential as a source of promising natural products for the development of antibiotics.
Ornithogalum boucheanum (Asparagaceae) in Eastern Europe: Native and synanthropic range, habitat conditions and state of population
Authors: Shynder O. I. , Nehrash Y. M. , Mamchur T. V. , Kostruba T. M.
Published: April 2023

The geographical distribution, ecological and coenotic features of the place of growth and age structure of Ornithogalum boucheanum populations in Ukraine have been studied. In total, during the entire period of floristic research in Ukraine, 263 native sites of this species were recorded in 13 administrative regions (oblasts). Mostly these sites are concentrated in the Steppe zone, where the main part of the Eastern European fragment of the general natural range of O. boucheanum is represented. For other regions of Ukraine isolated reports of the species are known. It is noted that in addition to reduction in the number of natural habitats of O. boucheanum within the Forest-Steppe and in the southern part of Ukraine Polissya, a secondary adventive natural habitat of the species is formed, where it is part of the immigration group of foreign taxa. It was found that the natural habitats of O. boucheanum are characterized by a certain stenotopy, as the species needs some moisture and is more common in valley and balka landscapes most often in large river basins, which are not prone to drying out and can be favourable ecological corridors for long-distance migration. Favourable conditions for O. boucheanum habitats exist in floodplain and riparian forests, which have sufficient moisture, little competition from other species of grass and a sufficient amount of light in the spring. In addition, O. boucheanum can successfully master artificial and synanthropic groups of tree species, in particular being widespread in the Forest-Steppe and Steppe Robinia plantations. It was found that populations of O. boucheanum in Ukraine have different numbers: with an area of 4–6 hectares, in which there are tens and hundreds of thousands of individuals, to small populations on the northern border of distribution, in Kirovohrad and Kharkiv oblasts, which have a of young invasive character. It is possible that modern conditions have been favourable for the spread of O. boucheanum in the transition zone between the Forest-Steppe and Steppe, and that the process of forming new populations of O. boucheanum is taking place here.
Chemical Profile and Bioactivity of the Essential Oil of Teucrium Takoumitense: An Endemic Lamiaceae from Southeast Morocco
Authors: Elbouny H. , El-Guourrami O. , Ouahzizi B. , El Hachlafi N. , Bammou M. , Sellam K. , Alem C.
Published: April 2023

The Teucrium genus is an important source of essential oil-bearing plants. The essential oils of this genus are endowed with important phytochemical diversity, exert widespread biological properties, and have several uses in traditional medicine. Teucrium takoumitense is an endemic aromatic and medicinal plant, grown in a very limited area in southeastern Morocco. To the best of our knowledge, there is no published report on the phytochemical or biological studies of Teucrium takoumitense essential oil (EO) harvested from the Errachidia region in Southeast Morocco. GC/MS analysis, total phenolic compounds, antioxidant, anti-inflammatory, and antibacterial tests on the EO of this plant were carried out in this study. The results of GC/MS analysis showed that β-ocimene (10.12%), δ-bisabolene (8.35%), linalool (8.16%), β-eudesmol (8.05%), and δ-cadinene (7.89%) are the major compounds in the EO. Important antioxidant activity (IC50 DPPH = 2.4 mg/mL, IC50 ABTS = 1.58 mg/mL, IC50 FRAP = 0.71 mg/mL, and TAC value = 230.72 AAE mg/g EO) and potent anti-inflammatory effect evaluated by phenol induced inflammation in rat ears were induced by the volatile oil. Moreover, the volatile oil induced antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. In conclusion, Teucrium takoumitense EO was found to be rich in volatile compounds and exert antioxidant, anti-inflammatory, and antibacterial properties. More studies are recommended to be evaluated on the extracts of this plant and conservation interventions need to be carried out to maintain its sustainability.
The Fana' Concept of Abu Yazid al-Busthomi and Imam Junaid al-Baghdadi (Comparative Study)
Authors: Nurkholis Ahmad , Haqq Muhammad Valiyyul
Published: April 2023

The concept of fana is a concept that developed in the third and fourth centuries hijriyah. A concept of fusion (trance) which later became an experience desired by many Sufism retainers. A Sufistic experience that must be passed and deliver Sufis at the top of the world of Sufism. with the experience that each Sufi feels so that many bring up various differences between one and another, then it also becomes a phenomenon for the fuqoha'. Abu Yazid al-Busthomi and Imam Junaid al-Baghdadi were one of the pioneers of the concept of Fana’. With a distinctly different background, between Sufi philosophy and Sunni. So the author takes the initiative and aims to combine the views between the two by examining a character who is balanced against and a character who has many adherents to this day, in order to get a good understanding and similarities or differences in the concept of Fana’'. This research uses library research, by means of qualitative analysis. As well as using primary and secondary sources. The results of this study are the concept of Fana’ must be together with the concept of Baqo’, awareness of a person's individuality has disappeared even though his physical form is still there. And to reach the peak of Fana’, the Salikin must leave the nature, character and personality as humans.
Etyka seksualna, małżeństwo i rodzina jako zniewolenie czy ostoja prawdziwej wolności? Analiza obrony małżeństwa i rodziny w pismach Gilberta Keitha Chestertona
Authors: Laskowska Ewa
Published: April 2023

Rewolucja kulturowa postępuje przez dzieje, niosąc wyzwolenie uciemiężonemu człowiekowi. Po oswobodzeniu go z ucisku klasy społecznej głosi ona wyzwolenie ze sztywnych norm kulturowych, etyki seksualnej, nierozerwalnego małżeństwa, trudności, jakie powoduje posiadanie rodziny, a nawet uwolnienie człowieka z okowów własnej, określonej płci. Czy jednak rzeczywiście jest to wyzwolenie? Zdaniem Gilberta Keitha Chestertona, który był świadkiem początków przemian społecznych, jakie następowały już na przełomie XIX i XX wieku, rewolucja obyczajowa może prowadzić do bardziej wyrafinowanej formy zniewolenia – zniewolenia umysłu. Artykuł przedstawia obronę etyki seksualnej, małżeństwa i rodziny proponowaną przez Chestertona, starając się odpowiedzieć na pytania, czy głos tego pisarza może być aktualny i intrygujący również współcześnie oraz czy może on ubogacić obecne spory nowym punktem widzenia.W odniesieniu do potrzeby wyzwalania się od norm pisarz odwraca perspektywę, ukazując, iż to nie katolicka etyka seksualna, nierozerwalność małżeństwa i rodzina są okowami zniewalającymi człowieka, lecz ciągłe zmiany, swoboda seksualna oraz rozwody – to one prowadzą bowiem do osłabienia ludzkiej woli i intelektualnego zniewolenia. Prawdziwa wolność ukryta jest natomiast, w sposób nieoczywisty i paradoksalny, właśnie w  przestrzeganiu etyki seksualnej, trwałym małżeństwie i rodzinie, które nie tylko stanowią chrześcijańskie ideały, ale są wyjątkowo racjonalne.
'Shaping Things': Design Fiction as a catalyst for design in design and technology education
Authors: IRVING-BELL DAWNE , McLain Matt , Wooff David
Published: April 2023

Inspired originally by the work of Bruce Sterling, this paper presents narrative accounts from experienced design and technology teachers who were introduced to the notion of “design fiction” during their teacher education programmes.
While training to teach as part of their subject study, pre-service teachers were introduced to the concept of design fiction. During their training they were encouraged to embrace the notion and use it as a catalyst to effect innovative pedagogical approaches in their teaching of design and technology. Specifically, to explore the advantages of using this concept as a tool not only on the effectual delivery of design, but in order to support the creation of a high quality conceptual outcome, where learning is concerned with innovation and the development of skill, rather than to produce a fully functional working model or artefact.
What Do Teachers Say about Young Children’s ICT Skills? An Investigation of Three Kindergartens in China
Authors: Yang Tian , Gunn Cathy
Published: April 2023

Information and communication technology (ICT) has become a ubiquitous component of many people’s daily lives. While some kindergartens have begun to pay attention to young children’s ICT skills, little is known about how teachers perceive this shift and in what ways they are emphasising these skills in kindergartens. Such research is particularly uncommon in China. This study explored how teachers perceive the significance of children’s ICT skills and how they taught these skills in kindergartens in China. By interviewing fifteen teachers in three kindergartens in Nanjing, this study found that participants generally considered ICT skills to be an important capability for children although they had various interpretations of their definition. Additionally, it was found that participants had different perceptions of how children could learn ICT skills in kindergartens. The analysis suggested that a clearer and shared definition of ICT skills should be provided by policymakers.
Coding and mathematics: How did coding and collaboration facilitate thinking?
Authors: Calder Nigel , Rhodes Kate
Published: April 2023

This paper reports on teachers’ perceptions of their students’ learning as part of a project examining the learning that took place when the students used ScratchMaths in their classroom programme. The project used design-based methodology, which incorporated video-recorded classroom excerpts, teacher interviews and teacher analysis and review of their practice. The teachers identified the students’ problem solving, use of unplugged activities and collaborating using explicit mathematical and coding language as ways to facilitate thinking. They also recognised that their own practice evolved into a more faciliatory role, while their understanding of coding processes grew through learning beside, and through, their students.
Powerful partnership: An exploration of the benefits of school and industry partnerships for STEM Education
Authors: Pattison Nicholas Peter
Published: April 2023

This article is based on the findings from a Master of Education dissertation, which explored the partnership between a junior school (Year 7–10) in New Zealand and VineLife Limited—a technology company based in Auckland. In this partnership, the students completed a design sprint, including a series of activities that required them to apply design thinking to a specific problem: investigating how to best use a sensor to scan trees within a forest for diseases. This article explores the benefits of such school–industry partnerships and shares insights gained from the research, including the benefits of exploring authentic problems, engaging with external audiences and encouraging student agency and critical thinking. Assertions are made about the need for a person to liaise between the school and industry to best enable Science, Technology, Engineering and Mathematics (STEM) based learning in schools.
Using emerging technology to draw learning across the curriculum
Authors: MacCallum Kathryn , Rimmer Tynneale , Le Comte Lee
Published: April 2023

To drive the wider adoption of STEM in schools, researchers have promoted the benefits of teaching STEM subjects integrated across the curriculum. This integration can support more authentic learning where learning is framed in real-world application or driven through problem/project-based learning. The integration of digital technologies (DT), where the learning moves away from consumption to creation, provides for further application of learning where the development of artefacts can situated within other subjects. This integration, however, raises new challenges for effective teaching and learning, and while new technologies and approaches can support this practice, this is still evolving. In this study we explore how one high school has integrated the creation of digital artefacts situated, in the DT class, with learning in the Māori Performing Arts class. The study explores how mixed reality (MR) combined with design thinking approaches, provide new opportunities to integrate learning and support engagement in STEM. Drawing on a participatory action research methodology, this article explores the experiences and perceptions of three teachers as they adopt MR to engage and teach students drawing on critical DT skills.
Chickenpox
Authors: Editorial Article
Published: April 2023

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Zagraniczne stosunki ekonomiczne pomiędzy Unią Europejską i Iranem a sankcje i bezpieczeństwo energetyczne
Authors: Obara Norbert
Published: April 2023

The article provides an analysis economical and political relationship between Islamic Republic of Iran and European Union and its members countries, particularly Greece, Italy and Spain in the context of politics of energy safety. Prior to the adoption of heavy economic sanctions the EU led a double track politics towards Iran: “carrot and stick method”. The main thesis is that sanction on Iran hurts more this country then EU but in some cases: Greece, Italy, Spain could have problems with new energy partners. Iran before sanctions was one of the main European suppliers of oil and natural gas but not for all EU, only for few countries. There are lists of main exporters and importers Iranians oil and natural gas in EU and the world. Additionally a list of EU sanctions on Iran has been attached. Additionally article presents roots of piece of Middle Eastern enemy history relationships between Great Britain, USA and Iran.
Polityka bezpieczeństwa jako narzędzie polityki Chińskiej Republiki Ludowej
Authors: Gierszewska Wioleta
Published: April 2023

The purpose of this article is to explore ‚Security’ as a policy tool in the Republic of China. Defense policy of the ‚Middle Kingdom’ [China] is an inseparable element of China’s foreign policy. Increased spending on militarization raises questions about the intentions of China’s foreign policy. It is worth noting that the ‚Middle Kingdom’ belongs to the group of world powers military, but China’s foreign policy largely determines its political and military force in the world and in the macro-region of the state of China. The limited communications and lack of mutual understanding of reality between Beijing and the United States cause unreasonable security concerns. On the basis of the content analyzed herein, one can conclude that the ‚Middle Kingdom’ strives to to become a superpower while increasing its army. The ambition for further militarization stems from a desire to gain greater prestige in the international arena and to ensure internal security and economic development.
Некоторые особенности экономического развития села в Восточной Галиции в 20–30-х годах хх века
Authors:   Akademia Wojsk Lądowych im. Hetmana Piotra Sahajdacznego we Lwowie, Выздрык Виталий
Published: April 2023

The article deals with the agrarian policy of the Polish government of the interwar period, which was intended to reform the agricultural system to increase productivity of agricultural production, the development of commodity-money relations and the activation of cooperative movement. The governmental policy has led to the formation of a land market, creating conditions for the origin of independent farms of different types and sizes, which were based on a private property of land. The main component of the agricultural policy of the government was colonization, which was intended to strengthen the eastern borders of the Second Polish Republic by creating economies of the colonists. They have become a social and political support for the government on the “Eastern lands.” This state policy influenced hostilely on millions of the local Ukrainian population. In despite the understanding of a significant number of Polish politicians and scientists such activities harm to the interests of the state, during the interwar period colonization of the land remained the main direction of agricultural policy. The Polish government has openly ignored the problems of the Ukrainian village, which led to a tangle of economic, national and social troubles that impacted on the Polish-Ukrainian aggravation of interethnic relations.
К вопросу о комплектации первых частей Галицкой армии
Authors: Шуминская Наталия
Published: April 2023

The following article focuses on the investigation of how the first Galician Army parts were formed, starting from November 1st protest to the adoption of military duty law. The article reflects research of how the army was formed by reorganizing of Ukrainian troops of the former Austrian army, and mobilization of volunteers. Based on the literature review (i.e. magazine articles, advertisements, messages, reports) the nature of protest, troop mobilization and military formation in various regions of eastern Ukraine is shown. The article describes the role of local officers and activists in creation of first Ukrainian divisions as well as issues associated with location and time of army creation.
Boris Buden, Strefa przejścia. O końcu postkomunizmu, Wydawnictwo Krytyki Politycznej, Warszawa 2012, ss. 188.
Authors: Wojtas Jarosław
Published: April 2023

Zone of transition: on the end of post-communism
Holoprosencephaly in Patau Syndrome
Authors: Schlosser Amanda de Souza , Costa Giovani José Coury , Silva Henrique Salmazo da , Mello Juan Luca Menezes de , Gomes Lucy de Oliveira , Onoyama Marina Michalski Oliveira , Costa Tatiana Martins Coury
Published: April 2023

ABSTRACT Objective: To evaluate radiological (gestational and perinatal) and neonatal signs of patients with Patau syndrome and semilobar holoprosencephaly, as well as to report the association of both pathologies. Case description: This case report is about a female infant, born at term with trisomy of the chromosome 13 and semilobar holoprosencephaly, with thalamic fusion and a single cerebral ventricle, in addition to several other changes that worsened the patient's prognosis. Comments: Chromosome 13 trisomy is a genetic alteration that leads to the symptoms that determines Patau syndrome. In this syndrome, cardiovascular, urogenital, central nervous system, facial structure and intellectual impairment are common, in addition to problems in limb formation, such as decreased humerus and femur length, polydactyly, hypotelorism and low ear implantation. It is estimated, however, that holoprosencephaly is present in only 24 to 45% of the patients with trisomy 13.
MEASUREMENTS OF SINUOUS WAVES ON MECHANICALLY FORCED RADIALLY EXPANDING FREE PLANAR LIQUID SHEETS USING CHROMATIC CONFOCAL MEASUREMENTS
Authors: Gyurkovich Alexander , Mehring Carsten
Published: April 2023

The chromatic confocal measurement technique is used to investigate the dynamics of radially expanding free liquid sheets generated by liquid jet impingement onto the flat end of a harmonically excited cylinder. Measurements of the sinuous-mode capillary waves are compared to experimental
results reported by Bremond et al. (2007) and analytical solutions from two inviscid linear theories: The "aerodynamic (wave-growth)" theory by Bremond et al. (2007), which considers the interaction between the liquid film and the surrounding gas phase, and the linear theory by Tirumkudulu and Paramati (2013) which neglects the gas phase surrounding the liquid sheet but predicts growth of
forced sinuous disturbances due to higher-order inertia terms associated with the thinning of the radially
expanding sheet (“thinning” theory). For liquid Weber numbers Wed based on impinging jet velocity and jet diameter which are larger than 800 and aerodynamically stable forcing conditions, agreement with "thinning" theory is found in terms of radial positions of nodes and anti-nodes of the
sheet disturbance envelope as well as growth of envelope maxima and minima. However, absolute amplitude values are significantly overpredicted in this case. For all other investigated operating conditions where instability due to film thinning is expected to dominate film dynamics (according to "thinning theory"), no such instability was observed experimentally. For most investigated cases,
"aerodynamic wave-growth" theory agreed better with the experimentally observed film behavior. The importance of the naturally most-amplified aerodynamic mode was considered but could not be quantified as part of the present investigation.
Geotecnologias aplicadas em estudos epidemiológicos sobre os casos de covid-19: revisão narrativa
Authors: Conceição da Silva Janiel , Pereira de Jesus Costa Ana Cristina , Gomes Nogueira Ferreira Adriana , Miranda Bezerra Janaína , Maia Pascoal Lívia , Stabnow Santos Floriacy , Santos Neto Marcelino
Published: April 2023

Justificativa e objetivos: a aplicação de geotecnologias é importante no auxílio do desenvolvimento de estudos epidemiológicos que visam identificar e distribuir eventos de saúde em populações e territórios específicos, além de verificar os fatores que influenciam na ocorrência desses eventos, com vistas à aplicação das evidências nas estratégias de planejamento e controle de doenças, como na pandemia de covid-19. Assim, o estudo objetivou apresentar as evidências científicas que vêm sendo produzidas sobre as geotecnologias aplicadas em estudos epidemiológicos sobre os casos de covid-19. Métodos: trata-se de uma revisão narrativa da literatura (RNL) de cunho descritivo. Para nortear o estudo, foi elaborada a seguinte pergunta de pesquisa: o que tem sido produzido sobre as geotecnologias aplicadas em estudos epidemiológicos sobre os casos de covid-19? A busca foi realizada em outubro de 2021, com emprego dos descritores Geographic Information Systems AND Covid-19 OR SARS-CoV-2 AND Epidemiology AND Spatial Analysis na Biblioteca Virtual de Saúde, Scopus, Web of Science, Portal CAPES. De forma complementar, foi realizada busca por boletins epidemiológicos e cartilhas no site do Ministério da Saúde do Brasil. Resultados: foram selecionadas 19 fontes de informação que se enquadravam nos objetivos para construção da discussão, sendo elencadas três categorias de análise: Aplicação das geotecnologias; Gestão da informação; Desafios dos estudos epidemiológicos que utilizam dados secundários. Conclusão: evidenciou-se o uso das geotecnologias em estudos epidemiológicos sobre a covid-19 na identificação de áreas de risco para a disseminação da infecção.
Bibliometric analysis of empirical studies on consumer behavior in the context of seven economic theories
Authors: Saglam Mehmet , Celik Zubeyir , Yigenoglu Kaan
Published: April 2023

Purpose- There is a research gap in which the most commonly used economic theories in consumer behavior literature are discussed, but conceptual themes are examined together with these theories. For this reason, this study aims to reveal the co-authorships, co-characteristics, co-economic theories, co-other theories, co-constructs, and co-keywords involved in the studies in the field of consumer behavior under seven economic theories.
Methodology- This study provides a bibliometric analysis of seven economic theories used in consumer behavior research published in Scopus, ESCI and/or SSCI and other indexes (eg EBSCO, ProQuest) between 2015 and 2021. For this purpose, 52 studies were selected through Google Scholar and analyzed with the VOSviewer program.
Findings- The study's findings determined that the number of consumer behavior research based on economic theories was higher in 2020–2021. The authors of the study were not co-authors of any other study. The vast majority of the studies were quantitative, and most of the studies were conducted in China and India. In addition to these results, it has been found that Impulsive Buying and Conspicuous Consumption are the theories used most in consumer behavior research. Also, a construct used in a study title based on any economic theory among the seven economic theories was not used in any working title based on any other economic theory. Finally, impulse buying, hedonic value, and Instagram were co-keywords for some studies based on Impulse Buying (Purchasing) Theory (IBT) or Conspicuous Consumption Theory (CCT).
Conclusion- In the discussion part, the study's contributions were included; and the study's limitations and suggestions for future research were given.

Keywords: Consumer behaviors, bibliometric analysis, seven economic theories, empirical studies, VOSviewer Program
JEL Codes: D11, M30, M31
Pointless labor, bullshit jobs, and organizational absurdity: new directions for institutional theory
Authors: Nikitina Daria
Published: April 2023

This essay is dedicated to the synthesis of two strands in the field of organizational studies, those of institutional theory and the study of meaningless labor. Institutional theory was one of the first to turn its attention to the inconsistent and ineffective actions performed within the organization, offering a conceptual apparatus for their analysis. Such phenomena, according to the institutional point of view, actually performed a certain function, allowing organizations to match the requirements of their institutional environment. However, over time, corporate reality became increasingly filled with labor which seemed meaningless and useless even to those who participate in it. Hence, institutionalism lost its explanatory power. Formed almost in parallel, the study of meaningless labor has analyzed these trends in the spread of stupidity, bullshit, and absurdity in modern organizations on alternative theoretical grounds. In this paper, I describe aspects that institutional theory can borrow from the study of meaningless labor, that is, the attention to personal dissatisfaction and the intentional organizational avoidance of any institutional rules.
Anthony Giddens and civilizational analysis: modernity between reflexivity and culture
Authors: Braslavskiy Ruslan
Published: April 2023

Based on the critical reconstruction of the diagnosis of modernity by A. Giddens, the article traces the logic of the transition from the institutional to the civilizational approach in the sociological discourse of “modernity”. The analysis focuses on the problem of the relationship between culture and reflexivity. In Giddens’ theory of radical modernity, reflexivity is opposed to culture, which is identified with tradition. According to the theory of multiple modernities that are genetically related to the sociological paradigm of civilizational analysis, tradition and reflexivity are correlated as two aspects of culture characterized by aspirations, on the one hand, to the reproduction of interpretive foundations that set a general context of meaning, and, on the other, to trans-contextual breakthroughs that open up new horizons of meaning. Both tendencies are in irreparable tension between themselves and are mediated in the capacity of culture to rationalization, during which the self-articulation of culture turns into its self-problematization. The combination of rationality with reflexivity leads to cultural innovation and interpretative shifts and, at least, potentially to new cultural crystallizations, allowing higher levels of self-problematization (J. P. Arnason). In different cultural and historical patterns, the ability to rationalize receives an uneven and specific development. Modernity is a “distinct civilization” (S. N. Eisenstadt), in which the tendencies of culture towards self-articulation in conflicting directions and towards self-problematization reach a level unprecedented in human history, giving rise to multiple configurations of social life intertwined with relatively autonomous dynamics of power and wealth. Although Giddens did not make a “civilizational turn” in his work, his institutional analysis of modernity closed with his formulating the problem of conjugation of culture and power, which is key for the civilizational approach in sociology. However, the same problematic also marked the limit of understanding modernity in Giddens’ theory; he recognized the incomprehensibility of the social world in which reflexivity was institutionalized. His further path was a one of utopian modeling and political implementation of the future post-modern world, rather than a one of scientific analysis of modernity.