bluuebunny/crossref_metadata_2025 huggingface dataset:
Training Needs Assessment of Health Care Professionals in Reproductive, Maternal and Newborn Health in a Low-Income Setting in Tanzania
Authors: Mbekenga Columba , Pallangyo Eunice , Mwansisya Tumbwene , Isangula Kahabi , Mwasha Loveluck , Orwa James , Mugerwa Micheal , Mantel Michaela , Subi Leonard , Mrema Secilia , Siso David , Selestine Edna , Temmerman Marleen , Edwards Grace
Published: December 2020

BackgroundHealthcare delivery globally and particularly in low-income setting is challenged by multiple, complex and dynamic problems. The reproductive, maternal and newborn health (RMNH) care is among the most affected areas resulting into high maternal and neonatal mortality and morbidity across the Sub Saharan region and Tanzania in particular. However, under-investment in adequate education and training of health care providers (HCPs) is reported worldwide and contributes to the critical shortages, and lack of adequate knowledge and skills among HCPs. The aim of this study was to assess the training needs among HCPs of RMNH care in selected health facilities of Mwanza, Tanzania. MethodsA cross-sectional descriptive and analytic survey using a self- administered questionnaire was conducted in 36 out of 80 health care facilities included in the Government of Canada and Aga Khan Foundation Canada funded Improving Access to Reproductive, Maternal and Newborn Health in Mwanza, Tanzania (IMPACT) project within the 8 Councils of Mwanza region in Tanzania. The training needs assessment (TNA) tool adapted from the Hennessy-Hicks’ Training Needs Assessment Questionnaire (TNAQ) instrument was used for data collection. The HCPs provided ratings on the importance of their task and their current performance of the task. The differences in scores were calculated to identify the greatest training needs. ResultsOut of 153 HCPs who responded to the TNA questionnaire, majority were registered (n=62) and enrolled (n=43) nurses. Ninety percent (n= 137) were from government-owned health facilities, mostly from hospitals 68 (45%). Training needs were high in 16 areas (out of 49) including cervical cancer screening and care; accessing research resources; basic and comprehensive emergency obstetric and newborn care; and sexual and gender-based violence. The overall perceived importance of the training needs was significantly associated with perceived performance of tasks related to RMNH services (Pearson Correlation (r) = .256; p <001).ConclusionsThe study highlights 16 (out of 49) training gaps as perceived by HCPs working in RMNH in Tanzania. The utilization of findings from the TNA has great potential to facilitate designing of effective trainings for local RMNH services delivery hence improve the overall quality of care.
Systemic Inflammatory Score Predicts Overall Survival In Patients With Cervical Cancer
Authors: Xu Mu , Wu Qibin , Cai Liangzhi , Sun Xiaoqi , Xie Xiaoyan , Sun Pengming
Published: December 2020

Background To evaluate the prognostic value of the systemic inflammatory score (SIS) in cervical cancer patients.Methods The optimal cutoff values for inflammatory biomarkers were calculated by X-tile software. The prognostic factors were investigated using univariate and multivariate Cox analyses. Time-dependent receiver operating characteristic (time-ROC) analysis and the concordance index (C-index) were used to compare the prognostic impact of factors. Results In total, 264 patients with cervical cancer were included in the study. The optimal cutoff value for lymphocyte-to-monocyte ratio (LMR) was 4.1. In multivariate analysis, FIGO stage, lymphovascular invasion, lymph node metastasis, preoperative serum albumin (Alb), and LMR were independent prognostic factors (P<0.05). Then, we combined preoperative Alb and LMR to establish the SIS. Multivariate analysis showed that the SIS was an independent factor that affected survival (P<0.05). When stratified by FIGO stage, significant differences in survival were also found for patients with different SISs (P<0.05). When the SIS and FIGO stage were combined, the time-ROC curve was superior to that of FIGO stage only. The C-index of the model combining the SIS and FIGO stage was 0.786 (95% CI 0.699-0.873), which was significantly higher than that of the model with FIGO stage only (0.676, 95% CI 0.570-0.782, P=0.0049).Conclusions The preoperative SIS is a simple and useful prognostic factor for postoperative survival in patients with cervical cancer. It might assist in the identification of high-risk patients among patients with the same FIGO stage.
Effect of Platelet Count on Prognostic Value in Patients with Chronic Heart Failure
Authors: Li Zhi , Jiao Zhenyu , Xie Yang , Li Yanbing
Published: December 2020

Background: The prognostic value of platelet count in chronic heart failure (CHF) is not clearly established. The present study aimed to assesse the independent prognostic value of platelet count in patients with CHF.Methods: From Januay 2016 to December 2019, 1162 patients with a discharge diagnosis of CHF were recorded in present study. The patients were divided into two groups according to the platelet count: low platelet count (LP, ≦140,000/μl) and high plate count (HP, >140,000/μl). The main outcomes were defined as all-cause death or cardiogenic rehospitalization within 3 years. Survival analysis and Cox proportional hazard models adjusted by an established risk score were performed. Results: During 3 years follow-up, the overall main outcomes including all-cause death (P=0.0475) and composite endpoint events of all-cause death or cardiogenic rehospitalization (P=0.0053) were higher in LP group than in those with HP group. After adjusting for other covariables, including gender, age, et al., low platelet count was related to increased the risk of main outcomes during 3 years follow-up (all-cause death, HR:1.151, 95%CI: 1.082-1.670, P=0.040; composite endpoint events, HR: 1.313, 95%CI: 1.152-1.964, P=0.016). Conclusions: Low platelet count was associated with risk for higher adverse outcome in patients with CHF.
An Oblique Cutting Based Mechanical Model For Insertion Torque of Dental Implant
Authors: Li Luli , Zhang Song , Li Quhao , Bian Cuirong , Zhang Airong
Published: December 2020

The insertion torque of a dental implant is an important indicator for the primary stability of dental implants. Thus, the preoperative prediction for the insertion torque is crucial to improve the success rate of implantation surgery. In this present research, an alternative method for prediction of implant torque was proposed. First, the mechanical model for the insertion torque was established based on oblique cutting process. In the proposed mechanical model, three factors, including bone quality, implant geometry and surgical methods were considered by defined bone-quality coefficients, chip load and insertion speeds, respectively. Then, the defined bone-quality coefficients for cancellous bone with the computed tomography (CT) value of 235~245, 345~355 and 415~425 Hu were obtained by a series of insertion experiments of IS and ITI implants. Finally, the insertion experiments of DIO implants were carried out to verify the accuracy of developed model. The predicted insertion torques calculated by the mechanical model were compared with that acquired by insertion experiments, which were agreed match with the relative error less than 15%. This method reduces the time consumption on establishing the fitting equations for different implants and enhance the predicted accuracy by considering the effects of implants’ geometries and surgical methods.
Chemical Composition and Larvicidal Activities of Essential Oils of Medicinal Plants, Artemisia Sieberi and Tanacetum Balsamita Against Malaria Vector, Anopheles Stephensi
Authors: Kazempour Samad , Shayeghi Mansoreh , Abai Mohammad Reza , Vatandoost Hassan , Pirmohammadi Masoumeh
Published: December 2020

Background: The country is suffering from malaria disease. There are several chemical control of mosquito. Due to resistant of vectors to different pesticides, this research was conducted to measure the chemical components and larvicidal activities of two native plants, Artemisia sieberi and Tanacetum balsamita against Anopheles stephensi.Materials and methods: Two species of medicinal plants were collected from different localities in in Iran. The plant samples were dried in shaded place and Essential Oils (EO) dried over anhydrous sodium sulfate. The EOs was maintained in the dark sealed vials until conduction larvicidal tests. The maximum storing of EOs was two days. The larvicidal tests were carried out based on the guideline of WHO. Results: The values of LC50 and LC90 of EOs were 47.9 and 178.8 ppm for Artemisia sieberi. The figure of 26.2and 52.4 ppm was observed for Tanacetum balsamita.The chemical constituents of Tanacetum balsamita and Artemisia sieberi which showed the highest efficacy for larviciding. A total of 39 constituents were isolated from Tanacetum balsamita .The main constituents were Thujone (52.37%) and Carvone (26.84%). Totally 57 constituents were detected in Artemisia sieberi and the main components were : camphor (23.6%) , 2-Ethyl-3- methyl maleic anhydride (15. 193%) and, Bombykal (10.32%) , Ethylbutenol (10.74%) .Conclusion: New formulations of plants should be prepared and then evaluated under semi-filed and filed conditions in a malrious areas.
Locally-developed External Fixators as Definitive Treatment of Open Tibia Diaphyseal Fractures: A Clinical Prospective Study Conducted in Ivory Coast
Authors: Kouassi Kouamé Jean-Eric , Akobé Jean Régis , Kouassi Aya Adélaïde Natacha , Founkoué Loïc , Detrembleur Christine , Kodo Michel , Cornu Olivier
Published: December 2020

Background: This study sought to evaluate the effectiveness of locally-developed external fixators (LDEF) as definitive treatment for open tibia diaphyseal fractures (OTDF) in Ivory Coast.Methods: Gustilo I, II and IIIA OTDFs of patients admitted within 24 hours of injury were prospectively included and treated with a locally-developed external fixator. The rates of union, mal-union, septic complications, as well as the functional results were assessed, in addition to the LDEF construct’s integrity. Predictive factors of failure or poor results were assessed.Results: Overall, 40 OTDF patients were admitted within 24 hours of injury. Gustilo I, II and IIIA fractures were observed in three, 13, and 24 patients, respectively. Uneventful fracture healing was obtained in 29 cases, with an average union time of 8.47 months. Mal-union and non-union were registered in three and four cases, respectively. Pin-track infection (PTI) was observed in 13 cases, and deep infection in seven. Infection resolved in all patients except four, who developed chronic osteomyelitis. None of the non-unions were associated with an infection. The overall functional result was satisfactory in 32 patients. PTI was the only predictive factor for chronic infection. Biplanar frames, when compared to monoplanar constructs, were associated with a significantly improved functional outcome.Conclusion: In comparison with the results obtained in the same environment without a locally-developed external fixator, the provision of such a device improved significantly the OTDF management, as it provided better stability and superior fracture healing rates. PTI remains an essential problem but with, hopefully, limited negative consequences. Trial registration: This study protocol was registered in Pan African Clinical Trial Registry under N°PACTR202009854874448. Date of registration 28 September 2020 ‘retrospectively registered’. www.pactr.org.
The Value of 18F-FDG PET/CT in Diagnosing Pancreatic Lesions: Comparison With CA19-9, Enhanced CT or Enhanced MR
Authors: Huang Shengyun , Chong Huanhuan , Sun Xun , Wu Zhijian , Jia Qing , Zhang Yongxue , Lan Xiaoli
Published: December 2020

Background: Pancreatic cancer is one of the most fatal tumors in the world, which incidence and mortality have continued to rise in the past decade. The main challenge in clinical practice for patients with pancreatic cancer is to accurately distinguish malignant lesions from benign ones in early evaluation. This research aims to investigate the value of 18F-FDG PET/CT in diagnosing pancreatic lesions, and compare it with CA19-9, contrast-enhanced CT (CECT), and contrast-enhanced MRI (CEMR).Methods: Cases of patients with suspected pancreatic lesions examined between Jan 1st, 2011 and June 30th, 2017 were retrospectively analyzed. CA19-9, CECT and CEMR within 2 weeks of PET/CT were evaluated. We compared the diagnostic efficacy of PET/CT with CA19-9, CECT and CEMR as well as combined tests.Results: A total of 467 cases were examined in this study, including 293 males and 174 females, with an average age of 57.79 ± 12.68 y (16–95 y). Cases in the malignant group (n=248) had significantly higher SUVmax (7.34 ± 4.17 vs. 1.70 ± 2.68, P < 0.001) and CA19-9 (663.21 ± 531.98 vs. 87.80 ± 218.47, P < 0.001) than those in the benign group (n=219). The sensitivity, specificity and accuracy of PET/CT were 91.9%, 96.3% and 94.0% respectively. Those for CECT were 83.6%, 77.8%, 81.2% respectively; and 91.2%, 75.0%, 81.7% were for CEMR. PET/CT corrected 14.7% (28/191) CECT diagnoses and 12.2% (10/82) CEMR diagnoses. Although the diagnostic efficiency of CA19-9 was acceptable (80.0%, 69.0%, 74.9% respectively), the joint application of PET/CT and CA19-9 could significantly enhance the diagnostic efficiency compared with PET/CT alone (sen 97.4% vs. 90.5%, P =0.0003; spe 100.0% vs. 95.2%, P = 0.0047). Conclusions: PET/CT has sensitivity similar to CECT, CEMR and significantly higher specificity and accuracy, helping reduce false diagnoses of morphological images. Combining PET/CT with CA19-9 could enhance diagnostic efficiency.
Knowledge, attitudes, and practices towards COVID-19 pandemic among residents of Jharkhand state, India: An online survey
Authors: Rai Arpita , Nishant Nishant , Singh D , Kulkarni Nitin , Chaurasia Shailesh , Pathak L
Published: December 2020

Background: People's adherence to control measures is imperative in the fight against COVID-19. The present study was done to evaluate knowledge, attitudes, and practices towards COVID-19 among residents of Jharkhand and to assist government in deciding further course of action during the COVID-19 outbreak. Methods: This study was an online cross sectional survey. The link to the questionnaire was displayed on the official website of Rajendra Institute of Medical Sciences, Ranchi, Government of Jharkhand, National Health Mission, Jharkhand, official website of all districts under Jharkhand state administration, Integrated Disease Surveillance Programme and Information & Public Relations department. Participation of residents in the survey was also extensively propagated using mass media mainly local television networks, radio channel and newspapers. Results: A total of 4683 responses were received from all districts of Jharkhand. Majority of the participants were young adults (47.5%) and number of male participants was more than the females (81.4%). Mean correct knowledge score for participants of this study was 10.73+2.2 (maximum attainable score was 14) while mean practice score for the participants was 4.5+0.69 (maximum attainable score was 5). Knowledge score of the participants was significantly associated with their age, education status and economic class (p<0.05). The participants largely held an optimistic attitude and healthy practices towards COVID-19. Conclusions: Participants had positive attitude but were also logically worried and uncertain about near future. Adequate knowledge of participants was visible in the practices of residents. There was however a gap across age groups, gender, literacy and income levels which should be addressed in future campaigns.
Genome-scale metabolic modelling underscores the potential of Cutaneotrichosporon oleaginosus ATCC 20509 as a cell factory for biofuel production
Authors: Pham Nhung TT , Reijnders Maarten , Suarez-Diez Maria , Nijsse Bart , Springer Jan , Eggink Gerrit , Schaap Peter
Published: December 2020

Background: Cutaneotrichosporon oleaginosus ATCC 20509 is a fast growing oleaginous basidiomycete yeast that is able to grow in a wide range of low-cost carbon sources including crude glycerol, a byproduct of biodiesel production. When glycerol is used as a carbon source, this yeast can accumulate more than 50% lipids (w/w) with high concentrations of mono-unsaturated fatty acids.Results: To increase our understanding of this yeast and to provide a knowledge base for further industrial use, a FAIR re-annotated genome was used to build a genome-scale, constraint-based metabolic model containing 1553 reactions involving 1373 metabolites in 11 compartments. A new description of the biomass synthesis reaction was introduced to account for massive lipid accumulation in conditions with high carbon to nitrogen (C/N) ratio in the media. This condition-specific biomass objective function is shown to better predict conditions with high lipid accumulation using glucose, fructose, sucrose, xylose, and glycerol as sole carbon source.Conclusion: Contributing to the economic viability of biodiesel as renewable fuel, C. oleaginosus ATCC 20509 can effectively convert crude glycerol waste streams in lipids as a potential bioenergy source. Performance simulations are essential to identify optimal production conditions and to develop and fine tune a cost-effective production process. Our model suggests ATP-citrate lyase as a possible target to further improve lipid production.
Structural stigma and its impact on healthcare for consumers diagnosed with Borderline Personality Disorder: protocol for a scoping review
Authors: Klein Pauline , Fairweather-Schmidt A. Kate , Lawn Sharon , Stallman Helen , Cammell Paul
Published: December 2020

Background Structural stigma in health systems experienced by consumers diagnosed with Borderline Personality Disorder (BPD), is a widespread phenomenon that causes major health inequities and harm for this population. Structural stigma in this context relates to institutional policies, cultural norms and organizational practices that limits consumers’ access to health services, quality of care, and capacity to achieve optimal health and well-being. BPD is a serious mental illness with high morbidity and mortality, characterized by instability in interpersonal relationships, self-image, and emotional and behavioral deregulation, which stem from significant traumatic childhood/life events, and/or biological aetiologies. The objectives of this scoping review are to explore the international literature on structural stigma in healthcare systems specific to BPD, and to provide an overview of the impact of structural stigma on health services for BPD consumers, and their carers/families.Methods This scoping review will follow the Joanna Briggs Institute (JBI) scoping review guidelines. We will search the following electronic databases (from inception onwards): MEDLINE, CINAHL, PsycINFO, Scopus, Cochrane Library and JBI-Evidence databases. Grey literature will be identified through the Google search engine. We will include all types of literature in English, published and unpublished, including any study design, reviews, clinical practice guidelines, policy reports, and other documents. No restrictions on publication date of sources of evidence will be applied. International literature should examine structural stigma associated with BPD in any healthcare setting such as, outpatients, inpatients, primary health care, or community-based facilities. Two reviewers will independently screen all titles, abstracts and full-text citations. Quality appraisal of the included sources of evidence will be assessed using the Mixed Methods Appraisal Tool (MMAT) 2018 version. Data analysis will involve quantitative (e.g., frequencies) and qualitative (e.g., thematic analysis) methods. Discussion This review is anticipated to enhance both identification and understanding of those structures in health systems (i.e., institutional policies, cultural norms, and practices), that manifest and perpetuate stigma experienced by consumers with BPD, and their carers/families. The findings can be used to inform future research, policy and practice relating to stigma reduction strategies that can be adopted to improve the provision of BPD-responsive services and care for this population. Scoping review registration This scoping review protocol was submitted for registration within Open Science Framework on 11th June 2020. This review protocol can be viewed via the following link: DOI 10.17605/OSF.IO/NWSVD
On the Rivers in the Euro-Atlantic Sky
Authors: Thandlam Venugopal , Rutgersson Anna , Sahlee Erik
Published: December 2020

We study the spatiotemporal variability of Atmospheric Rivers (ARs) over Euro-Atlantic region using long-term reanalysis datasets. Winds, temperature and specific humidity at different pressure levels during 1979-2018 are used to study the water vapour transport integrated between 1000-300 hPa (IVT300) as a proxy to ARs. The intensity of ARs in the North Atlantic has been increasing in recent times (2009-2018) with large decadal variability and poleward shift (~5o towards the North) in landfall (1999-2018). Significant bias shown by different reanalysis products in IVT300 compared to ERA5 data is attributed to bias in specific humidity and winds. Different reanalysis datasets show similar spatial patterns of IVT300 in mapping ARs but has a bias of around 40-60 kgm-1s-1 compared to ERA5. The magnitude of winds and specific humidity in the lower atmosphere (below 750 hPa) dominates the total column water vapour and intensity of Ars in the north Atlantic. IVT300 in all reanalysis datasets in the North Atlantic show a standard deviation of 200 kgm-1s-1 which is around 60% of the IVT300 climatology (>300 kgm-1s-1). Though ARs have higher frequency of landfalling over Western Europe in winter half-year (WHY); the intensity of IVT300 in winter is 3% lower than the annual mean. On the other hand, lower frequency of ARs in summer half-year (SHY) shows 3% higher intensity than the annual mean. There is a significant impact of the North Atlantic Oscillation (NAO) and Scandinavian blocking on the location of landfall of ARs. Furthermore, there is a strong latitudinal dependence of the source of moisture flux in the open ocean, contributing to the formation and enhancing AR's strength.
Polygenic Risk Score is a Predictor of Adenomatous Polyps at Screening Colonoscopy
Authors: Northcutt Michael , Shi Zhuqing , Zijlstra Michael , Shah Ayush , Zheng Siqun , Yen Eugene , Khan Omar , Beig Mohammad Imran , Imas Polina , Vanderloo Adam , Ansari Obaid , Xu Jianfeng , Goldstein Jay
Published: December 2020

Background: Single nucleotide polymorphism (SNP)-based polygenic risk scoring is predictive of colorectal cancer (CRC) risk. However, few studies have investigated the association of genetic risk score (GRS) with detection of adenomatous polyps at screening colonoscopy. Methods: We randomly selected 1,769 Caucasian subjects who underwent screening colonoscopy from the Genomic Health Initiative (GHI), a biobank of NorthShore University HealthSystem. Outcomes from initial screening colonoscopy were recorded. Twenty-two CRC risk-associated SNPs were obtained from the Affymetrix™ SNP array and used to calculate an odds ratio (OR)-weighted and population-standardized GRS. Subjects with GRS of <0.5, 0.5-1.5, and >1.5 were categorized as low, average and elevated risk.Results: Among 1,769 subjects, 520 (29%) had 1 or more adenomatous polyps. GRS was significantly higher in subjects with adenomatous polyps than those without; mean (95% confidence interval) was 1.02 (1.00-1.05) and 0.97 (0.95-0.99), respectively, p<0.001. The association remained significant after adjusting for age, gender, body mass index, and family history, p<0.001. The detection rate of adenomatous polyps was 10.8%, 29.0% and 39.7% in subjects with low, average and elevated GRS, respectively, p-trend <0.001. Higher GRS was also associated with early age diagnosis of adenomatous polyps, p<0.001. In contrast, positive family history was not associated with risk and age of adenomatous polyps.Conclusions: GRS was significantly associated with adenomatous polyps in subjects undergoing screening colonoscopy. This result may help in stratifying average risk patients and facilitating personalized colonoscopy screening strategies.
A selection pressure landscape for 870 human polygenic traits
Authors: Song Weichen , Pan Weihao , Qian Wei , Wang Weidi , Yu Shunying , Zhao Min , Lin Guan Ning
Published: December 2020

Characterizing the natural selection of complex traits is essential for understanding human evolution and biological or pathological mechanisms. To fulfill this requirement, we leveraged Genome-wide summary statistics for 870 polygenic traits and quantified the selection pressure of different forms and time scales on them in European ancestry. We found that 88% of traits underwent polygenic adaptation in the past 2000 years. At the present time and Neolithic period, selection pressure showed profound alteration. Traits related to pigmentation, impedance, and nutrition intake exhibited strong selection signals across different time scales. Our result provided an overview of selection pressure on various human polygenic traits, which served as a foundation for further populational and medical genetic studies.
Preliminary Results of Tocilizumab and Interferon α-2β Treatment of SARS-CoV-2.
Authors: Fleming M PhD Richard M , Fleming NRP BA BS Matthew R
Published: December 2020

Seven patients receiving Hydroxychloroquine (HCQ) and Zinc (Zn) for CoVid-19 with PCR positive results were admitted to hospital after failing to improve. Following NCT04349410 protocol and failure to improve with elevated interleukin-6 and ferritin levels, patient’s treatment were changed following measurement of Corona Virus Pneumonia (CVP). Follow up measurements of CVP confirmed improvement with combined intravenous Tocilizumab, Interferon α-2β nebulizer, Atrovent nebulizer and SQ heparin treatment
THE RELATIONSHIP BETWEEN KNOWLEDGE MANAGEMENT PROCESS ON INFORMATION AND COMMUNICATION TECHNOLOGY DIMENSIONS AND THE CONTRIBUTION OF COMPETITIVE ADVANTAGE IN PROFESSORS OF PHYSICAL EDUCATION FACULTIES
Authors: Kalashi Maziyar , Azizi Bisotoon , Bakhshalipour Vahid , Sareshkeh Siavash Khodaparast
Published: December 2020

Today, attention is paid to the importance and special position of information and communication technology (ICT) with the rapid growth of technology that has affected all aspects of organizations in some way and it is one of the components of modern societies. The purpose of this study was to examine the effect of the knowledge management process on ICT dimensions and the contribution of competitive advantage in professors of physical education and sport sciences faculties in Islamic Azad University Branches. This study was an applied and descriptive-correlation research. The population of this study was 86 professors. The collected data were analyzed by K-S tests and Pearson and Spearman Correlation Coefficient. The results showed that 59.30 % of subjects had doctorate or were PhD students, 40.70 % of them had a Master’s degree, 63.66 % of them were men, and 36.04 % of them were women. The results also showed that there was a significant relationship between the knowledge management process with ICT (0.710), the knowledge management process and the contribution of competitive advantage (0.619), and the contribution of competitive advantage with ICT (0.612). The use of ICT enables educational organizations to benefit from their intellectual advantages. It is suggested, that physical education and sport sciences faculties pay special attention to the promotion of their employees’ knowledge, more use of information technology, and the creation of a culture that is full of competition for success in their organizational mission.
ROLE AND IMPORTANCE OF THE PLAYING SPACE IN PSYCHIC DEVELOPMENT OF A PRE-SCHOOL CHILD
Authors: Bondar Oksana
Published: December 2020

In the research process it has been determined, that the full-value development of a pre-school child takes place at the expanse of high-quality organization and effective use of the playing space. It has been outlined, that high-quality organization of the playing space favors the harmonic combination of psychic, physical and spiritual development of a child. The conducted theoretical analysis allowed to separate four main components that must be taken into account in the process of organizing the high-quality playing space of pre-school children, namely: content, material, organizational and personal. It has been noted, that a structural model of the qualitatively organized playing space of a pre-school child is based on acknowledgement of the child-centered orientation priority. It has been proved, that the agreed combination of four components of the playing space provides psychological safety of a pre-school child and favors the high level development of its cooperation in the process of interaction with others. It has been revealed, that the content of realized playing actions, material filling of the playing space, its dynamics and mobility, inclusion of all children in the active playing activity need essentially other approaches. There have been fixed contradictions between necessary and real ideas of teachers as to the organization quality of the playing space for pre-school children.
The problem of quality organization of the playing space for pre-school children gains special importance under conditions of modern society that dictates new rules and requirements to the development of a successful person. The formation of the high level ability to understand own possibilities, to reveal initiative and comprehensively realize themselves in pre-school children provides the presence and interconnection of all structural components of the playing space.
Datum ranking and analysis of factors affecting tire wear
Authors:   Saint-Petersburg Mining University, ABDULAEV El’dar Kamil’evich
Published: December 2020

Relevance of the work. The operational efficiency and technical condition of mining vehicles to a large extent depend on the service life and performance characteristics of tires. The most important technological process that determines the effectiveness of field development is the transportation of rock mass. The share of motor transport costs in the total cost and production by open method at Russian mining enterprises is significant, and reaches 70% as the depth of open pits (cuts) increases. At the same time, the actual productivity of mining trucks is much lower than their technical and technological capabilities, and this difference is up to 2.5 times or more for various brands of vehicles, including imported ones. Today, both consumers and manufacturers of large tires are interested in the most efficient tire production management. Purpose of the work: consideration of the main factors affecting tyre life, as well as datum ranking of these factors to determine the degree of significance of each factor. Methodology of research. The systematic approach was used including datum ranking method, some analytical, computational methods and generalization. Results. The ranking was carried out by three independent groups of experts on a number of proposed factors. The main factors in each group were identified and the degree of agreement between the opinions of the interviewed specialists was evaluated. The general opinion of various expert groups on the significance and ranking of factors affecting the integrity of giant tires is confirmed. Conclusions. Datum ranking and analysis of factors affecting the wear of giant tires of mining dump trucks significantly affect the optimization of machine operation and, with appropriate adjustments, can give a positive economic effect.
Demantoid from the Telyansky Klyuch deposit (Middle Urals) – is the place of the first discovery in the Urals
Authors:   LLC “Berezovskiy rudnik”, KROPANTSEV Sergey Yur’evich
Published: December 2020

The relevance of the work is due to the need to study the Ural gems, including those discovered in the Urals. This is important not only from a scientific point of view, but for the history of science and the development of geological tourism in our region as well. Purpose of the work: study of the chemical composition of demantoid from the Telyansky Klyuch deposit, which is the site of the first find of this gem in the Urals. Research methodology. Demantoid (green jewelry andradite) was washed by the author in the Telyansky Klyuch gold placer; the quantitative analysis of the chemical composition of garnet was performed using the JXA-733 X-ray electron probe microanalyzer. Results. A historical study of the sites of finds of demantoids in the Middle Urals was carried out. It was established that precious garnet was found not in placers of the Bobrovka river located south of Nizhny Tagil, but in the gold placer of the Telyansky Klyuch to the north of Nizhny Tagil. Microprobe analysis of individual demantoid crystals showed that garnets with different green color saturation according to the main components are andradites with average contents: CaO – 33,18%; Fe2 O3 – 30,74%; SiO2 – 35,02% (for 6 analyzes). The feature of the chemical composition of Telyansky demantoids is the absence or insignificant amount of aluminum impurity in them – not more than 0.02% Al2 O3 , which is practically at the level of microprobe analysis sensitivity for this element. The amount of chromium varies from 0.02% Cr2 O3 in a light green demantoid to 0.5–0.74% Cr2 O3 in green and bright green andradites. Conclusions. The place of the first find of low-impurity and chromium-containing andradites in the Urals with the name of “diamantoite” (proposed by N. G. Nordenskiöld ) is the Telyansky Klyuch gold deposit on the East Tagil dunite-harzburgite massif in the Middle Urals
Development of criteria for determining the color saturation of gemstones
Authors:   Ufa State Petroleum Technological University, ZUBOV Roman Nikolaevich
Published: December 2020

The urgency of the problem is conditioned by spectral methods development providing objectivity and accuracy of gemstones color grading. The purpose of the work: working-out the criteria which allows to determine gemstones saturation based on physicsmathematics patterns and spectral data. Methodology of the research: studying of colored gemstones transmittance spectra, discovery of the regularities and development of physics-mathematics methods for the color saturation grading. Results. The absolute and relative criteria for gemstone saturation grading was suggested as ratio of difference between light transmittance to squared difference between wavelengths at the area of basic chromophore element. Experimental data and allochromatic gemstones saturation calculation examples were presented considering spectral sensitivity of human eye. Summary. Gemstones absorption and transmittance spectra research allows to define tone and saturation gemstone color features. To improve tone and saturation definition accuracy, it is necessary to select standard hue of gemstones for wavelengths scale graduating along with spectral sensitivity of human eye.
Improvement of the mining technology in the diatomite mine, Algeria
Authors:   Peoples’ Friendship University of Russia (RUDN University), LAMAMRA Abdessattar , EREMENKO Vitaliy Andreevich ,   Peoples’ Friendship University of Russia (RUDN University), NEGURITSA Dmitriy Leonidovich ,   Sergo Ordzhonikidze Russian State Geological Prospecting University
Published: December 2020

Relevance of the work. After the recent drop in oil prices, which is Algeria’s main income, Algeria has been forced to increase production in the mining sector. Purpose of the work. Algeria seeks to increase the production of the Diatomite Deposit in the sig mine west of Algeria, but the geological conditions and geotechnics of rocks whose resistance to them is weak, are among the most important problems that hinder the increase in production. The currently used room-and-pillar development system does not meet the mining conditions of the development of the Diatomite Deposit, the conduct of preparatory and cleaning works is constantly accompanied by collapses of roof rocks. Results. To ensure an increase in productivity to 100 thousand tons of Diatomite per year and above, it is necessary to reequip the mine with a change in the technology of the method of its production. Conclusions. The introduction of a longwall development system with a mechanized treatment complex, which is widely used in the coal industry, will significantly help to increase Diatomite production, ensure the safety of underground mining operations and increase the resource efficiency of the field.
Prospects for the implementation of the state information system for waste management (using the Tyumen region as an example)
Authors:   LLC ʺMNP ʺGeodataʺ, PETROV Yuriy Vladimirovich , PROSKURIN Grigoriy Aleksandrovich ,   LLC ʺMNP ʺGeodataʺ
Published: December 2020

Relevance of work. One of the main state tasks is the organization of balanced management of production and consumption waste. An effective tool for integrated management in this area is the implementation of the state information system. The research results will contribute to the development of regional environmental monitoring based on modern digital technologies. Purpose of the work: to study the current prospects for the implementation of the state information system for the management of production and consumption waste in the region (Tyumen region without autonomous okrugs). Methods of research. The collection and systematization of information on the organization in the region of the management of production and consumption waste, including existing technologies for remote environmental monitoring, have been completed. A spatial digital model of the regional waste management is formed, on the basis of which the proposed solutions for the state information system have been tested. Statistical and geoinformation methods of study were used. Results. The system for managing waste from production and consumption, which has been formed in the Tyumen Region, as well as information support for government bodies for making managerial decisions, does not correspond to modern challenges and existing potential. Existing issues in the way of a comprehensive state information representation of the industry are considered. Conditions and prospects for the implementation of the state information system at the regional level are systematized. Conclusions. Using the Tyumen region as an example, the prospects for introducing a state system for the management of production and consumption waste were determined, and managerial measures in this direction were outlined.
The dynamic Nash bargaining solution for 2-stage cost sharing game
Authors:   St. Petersburg State University, Li Yin
Published: December 2020

The problem of constructing the Dynamic Nash Bargaining Solution in a 2-stage game is studied. In each stage, a minimum cost spanning tree game is played, all players select strategy profiles to construct graphs in the stage game. At the second stage, players may change the graph using strategy profiles with transition probabilities, which decided by players in the first stage. The players' cooperative behavior is considered. As solution the Dynamic Nash Bargaining Solution is proposed. A theorem is proved to allow the Dynamic Nash Bargaining Solution to be time-consistent.
Optimal pricing structure in a maintenance contract: a game theory approach
Authors:   Federal Rural University of Pernambuco, Santos Henrique P. Z. , Guedes Bruno N. ,   Federal University of Pernambuco, Cristino Claudio T. ,   Federal Rural University of Pernambuco
Published: December 2020

This essay presents a novel look at Murthy and Asgharizadeh's study (Murthy & Asgharizadeh, 1998). The authors developed a decision problem applied to maintenance outsourcing involving two decision-makers (players). If a consumer buys a product, then outsources the maintenance actions to a maintenance agent (agent) who offers two maintenance options; a maintenance contract that holds a penalty clause which is activated if the agent's time to repair is higher than a specified time, and services on-demand. The model yields equilibrium strategies based on the subgame-perfect Nash equilibrium. The agent defines the optimal pricing structure for the maintenance options considering the equipment's useful life while the consumer maximizes their expected payoff by choosing one maintenance option. Our contribution to this research branches in three ways. First, once the model deals with random variables, it represents a stochastic optimization problem. We propose a different approach to estimate this penalty time by using the Monte Carlo method. The second contribution is to present a formal definition of this decision problem as a game, emphasizing the game theory's components. Finally, we reinterpret the players' equilibrium strategies.
Synthesis of Pyridine Clubbed 2,5-Disubstituted-1,3,4-Oxadiazole Derivatives Shows Potent Antimicrobial Activity
Authors: Katiyar Pratima , Singh Manjul Pratap
Published: December 2020

In the present study, a series of 2,5-disubstituted-1,3,4 oxadiazole analogues retaining pyridine
moiety were synthesized (4a-j) by reacting various substituted aromatic acids and isonicotinohydrazide
by using POCl3 as a cycling agent. The structure elucidation of all the synthesized compounds
was done by chromatographic data and spectral data analysis. The synthesized compounds were evaluated
for their in-vitro antimicrobial activity against various strains of ESKAPE pathogens. Antibacterial
activity was performed against Bacillus subtilis, Escherichia coli, Staphylococcus aureus and
Pseudomonas aeruginosa, while antifungal activity was assayed against Candida albicans and Aspergillus
spp. The result of in-vitro antimicrobial studies of all the synthesized compounds revealed that
compound 4d and 4f exhibited promising activity against selected microbial strains equally compared
to Cefixime and Econazole used as reference drugs.
Recent Patents on Electrochemical Machining of Shaped Holes
Authors: Li Zhaolong , Cao Bingren
Published: December 2020

Background:

Electrochemical Machining (ECM) can machine most conductive materials
and is not limited by physical properties of materials such as strength, hardness and toughness. However,
the process of ECM is unstable as the structure of tool electrode, electrolyte composition and the
machining device of ECM will affect machining accuracy and stability of shaped holes. Therefore, people
pay more and more attention to the development trend of ECM of shaped holes.

Objective:

In order to increase machining accuracy and machining stability of ECM of shaped holes,
ECM method has been constantly improved.

Methods:

This paper reviews various representative patents and papers on ECM of shaped holes at
home and abroad.

Results:

By summarizing a large number of patents and papers about ECM of shaped holes, this paper
analyzes the structure of tool electrode, electrolyte composition and the machining device of ECM, and
the development trend of ECM of shaped holes is also discussed.

Conclusion:

The optimization of the technological equipment and process of ECM of shaped holes is
beneficial to improve the machining accuracy and the machining stability of shaped holes. More interrelated
patents on ECM of shaped holes will be invented later.
Design of Interactive Multimedia Learning Vocabulary for Students Communication Disorder and Deafness During the Covid-19 Pandemic
Authors: Jayanegara I Nyoman , Setiawan I Nyoman Anom Fajaraditya , Putri Gusti Agung Meirany
Published: December 2020

The development of technology is very helpful in teaching and learning in general. However, these developments can also be used for students with disabilities, especially those who have communication disorders and deafness. But in reality, teachers are still limited in managing the development of teaching materials even though school facilities are sufficient to do that. This is very reasonable considering the limitations of educators who must specifically focus on trends in the development of technology-based education. The interactive method is one alternative solution, especially the role of multimedia technology in learning media. At the school for students with disabilities in Denpasar, SLB B Sidakarya for the category of communication disorder and deafness requires the media to follow these developments. In the initial design stage, taking vocabulary content for grade 1 students, by gathering various data needs, especially from the users, namely teachers and students. The data then becomes the basis for designing interactive multimedia vocabulary learning, which is the basic development of several subjects. The media will have a positive impact, especially increasing student interest in school, with files that are relatively lightweight and processed in design research, expected to be easier for students to learn. This media can also be a medium to help when students study at home, especially the Covid-19 pandemic period, certainly helped by collaboration between the school and design practitioners. In addition to vocabulary, it is also expected to be able to motivate development in other media to assist persons with disabilities in learning, especially in pandemic situations.
Education Budget Politics: Is It Pro-Disabilities? Case of Yogyakarta Municipality, Indonesia
Authors: Rahmat Al Fauzi , Purnomo Eko Priyo , Mutiarin Dyah , Malawani Ajree Ducol
Published: December 2020

This article aims to examine the education budget policy allocated for inclusive education programs, wherein providing a budget is highlights. In this context, Yogyakarta City government is submit because of its embracement unto inclusive budget post for education. This paper used a qualitative approach with document-analysis method to analyze the inclusive education budgets from 2017 to 2019. The research findings are; first, the budget allocation for inclusive education is considering to be minimal when compared to other program budget posts. In 2017, budget allocation was only 1.02%, in 2018 amounted to 1.05%, and in 2019 1.19% of six programs set out in the educational development program objectives. Second, a critical review of the budget and realization of 2017 to 2019 inclusive education program has found to be not optimal absorbed as desired achievement targets. Even so, the evaluation of budget absorption includes in the high category on performance appraisal. Third, the number of inclusive schools and the percentage of teachers according to qualifications from 2017 to 2019 has been increasing. Fourth, the budget for the education development program in 2017 to 2019 has declined. Nevertheless, more importantly, the budget heading for inclusive management education in 2017 and 2019 has increased. Therefore, this has proven that the Yogyakarta City government has committed to realize inclusive education and deserves to establish as a region that cares about inclusive education.
Мощность излучения сильноточной вакуумной дуги, стабилизированной аксиальным магнитным полем, в видимой и ультрафиолетовой областях спектра
Authors: Баринов Ю.А. , Забелло К.К. , Логачёв А.А. , Полуянова И.Н. , Шерстнев Е.В. , Школьник С.М.
Published: December 2020

A silicon photodiode, was used to measure the power emitted by a vacuum arc in the ultraviolet and visible spectral regions. The measurements were carried out with the high-current vacuum arc stabilized by an axial magnetic field in regimes with developed anode activity. The power of radiation coming out of the arc through the side surface was measured. The results show that when analyzing the energy balance of a high-current vacuum arc, radiation must be taken into account.
AlSb/InAs-гетероструктуры для СВЧ-транзисторов
Authors: Суханов М.А. , Бакаров А.К. , Журавлёв К.С.
Published: December 2020

The paper describes the features of the MBE growth process of AlSb / InAs heterostructures with a high-mobility two-dimensional electron gas for UHF transistors with ultra-low power consumption. The main stages of manufacturing transistors based on AlSb / InAs heterostructures are outlined. The drain and transfer characteristics of transistors are presented and discussed.