bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimization of the Protocol for Isolation of Exosome and Secretome of CACO-2 Colorectal Adenocarcinoma Cells from Conditioned Media for Subsequent Mass Spectrometric Analysis
Authors: Shushkova N.A. , Novikova S.E. , Farafonova T.E. , Zgoda V.G.
Published: April 2020

The conditioned media in which the tumor cells are cultured represents a model object for studying of secretome and proteomic composition of exosomes. This pool of proteins is of particular interest in terms of the search for potential markers of malignant diseases. The efficiency of the isolation of exosomes and secretome from the cell culture media largely determines the success of their analysis by the mass spectrometric method. In this paper, we have applied various approaches to isolate secretome and exosomes originated from Caco-2 colorectal adenocarcinoma cells. The combination of ultrafiltration and centrifugation provided a deep proteomic analysis of the secretome and exosomes obtained from the one initial volume of conditioned medium without the addition of fetal bovine serum. Applying tandem mass spectrometric analysis we have identified 436 secreted proteins. In exosomes, the characteristic proteins ALIX, CD63, syntenin, lactadherin (MFGE8) were identified. Using targeted mass spectrometry, the exosome markers CD82, CD9 and HSPA8 were determined at the levels of 0.08 ± 0.03 fmol/μg, 0.13 ± 0.03 fmol/μg and 2.6 ± 0.02 fmol/μg of total protein, respectively. Among the secreted proteins, there were many markers associated with tumor progression and metastasis, such as DAG1, PODXL, LRRN4, TGFBI, IL6ST, DSC1, DSG1, and NPC2.
Management of pre-eclampsia and its complications in the department of gynecology and obstetrics at Donka national hospital Conakry, Guinea
Authors: Boubacar Diallo Alpha , Bah Omou Hawa , Conté Ibrahima , Sow Ibrahima Sory , Bah Ibrahima Koussi , Touré Souleymane , Lamah Monique , Diallo Boubacar Poreko , Lapko Mamy Ernest , Keita Namory , Baldé Mamadou Djoulré
Published: April 2020

Background: Vascular-renal syndrome, also known as pre-eclampsia, is a condition specific to pregnancy, usually occurring in the last trimester of pregnancy. Pregnant women are sometimes at risk of unpredictable obstetrical complications such as: hemorrhage, kidney failure, HELLP syndrome, sometimes even brain damage requiring prompt care and multidisciplinary collaboration. Vascular-renal syndromes are the third leading cause of maternal death and also the world's leading cause of perinatal death. Objectives of this study were to analyse the management of vascular-renal syndromes. Calculate their frequency, describe the sociodemographic characteristics of patients, describe the clinical and biological signs of patients, evaluate the maternal-fetal prognosis.Methods: The study was conducted in the department of obstetrics and gynecology of Donka National Hospital. It was a prospective, descriptive, cross-sectional, 6-month study from March 1st to August 31st, 2015, of pregnant women with pre-eclampsia.Results: The study included 217 cases of pre-eclampsia out of a total of 3054 patients, i.e. a proportion of 7.10%. The proportion of pre-eclampsia was high in patients aged between 15 and 19 years, housewife, married, primary. The predisposing factors were primigestitis, obesity and twinkling. The clinic was dominated by headaches and visual disturbances. Severe preeclampsia in 78.49%, eclampsia in 21.65% or simple hypertension in 1.75%. Maternal and fetal complications were dominated by eclampsia 26.26%, PPH (2.63%), eclamptic coma (0.46%), acute fetal distress 27.19%, and fetal death in utero (11.40%). In order to improve maternal and fetal prognosis it is necessary to provide multidisciplinary care, which unfortunately is not always available in our context.Conclusions: Obstetric emergency is a frequent situation for which a better management would improve the maternal-fetal prognosis.
A comparative study of intravenous iron sucrose versus oral iron therapy in iron deficiency anemia during postpartum period
Authors: Khajotia Santosh , Meena Shubha , Naraniya Deepak
Published: April 2020

Background: Anemia is the commonest major contributing factor in maternal mortality and morbidity in developing countries and according to World Health Organization (WHO) criteria, it contributes to 20% of maternal deaths. Anemia in pregnancy defined as haemoglobin level <11 gm/dl (7.45 mmol/L) and haematocrit less than 33% (WHO). Aim of this study was to compare the efficacy of oral iron ferrous sulphate therapy with intravenous iron sucrose therapy in the treatment of iron deficiency anemia during postpartum period.Methods: This was a prospective randomized comparative clinical trial single center study conducted on 200 postpartum women aged >18 years (after normal delivery or LSCS) within 10 days of delivery with Hb level more or equal to 6 gm/dl but less than 10 gm/dl were included in the study. This was a one-year study conducted during 1st December 2018 to 30th November 2019.Results: There was a significant increase in the hemoglobin level in both the groups i.e. in IV iron group, from 8.26±1.03 gm/dl on day 1 to 11.62±0.94 gm/dl on day 45 as compared to oral iron group, from 8.24±1.09 gm/dl on day 1 to 11.07±1.14 gm/dl on day 45; and serum ferritin level from 41.69±40.45 ng/ml on day 1 to 77.34±41.60 ng/ml on day 45 in IV iron group as compared to the oral iron group from 22.20±8.82 ng/ml on day 1 to 31.72±9.72 ng/ml on day 45. So, there was a rapid increase in both hemoglobin and serum ferritin levels in IV iron group as compared to the oral iron group.Conclusions: Intravenous iron sucrose administration increases the hemoglobin level and serum ferritin more rapidly in compare to the oral intake of ferrous sulphate in women with iron deficiency anemia in postpartum women in our study.
Study of maternal and perinatal outcome in abruptio placentae
Authors: Patel Krupa , Bhatu Jaydeep , Patel Swati
Published: April 2020

Background: Abruptio placentae is very frequently seen in our population. Few studies have reported maternal and fetal morbidity and mortality associated with this condition. No work has been done on abruptio placentae in our setup. The data generated will help to improve maternal and fetal morbidity and mortality by planning prompt management of future cases of placental abruption. Objective of this study was to study possible etiological factors of abruptio placentae, analyse maternal outcome, perinatal outcome in the form of maternal morbidity and mortality and discuss possible preventive measures and future management optionMethods: The retrospective observational study it was included all cases presenting with ante partum haemorrhage during the study period. Subjects selected for the study were all cases diagnosed as having abruptio placentae. All other causes of APH like placenta previa and other extraplacental causes were excluded.Results: In the present study incidence of abruptio placentae is higher in 25-30 year that were 42.5% and more in 2nd gravida patient. PIH was accounting for 50%, most of the patients (95%) were anaemic at admission and majority of them required blood transfusion.one maternal mortality (2.5%) occurred, perinatal mortality was 75%.Conclusions: Abruptio placentae serious condition with manifestation of significant maternal and perinatal morbidity and mortality. Complications can be reduced by provisional antenatal care to every woman and with improvement in medical facilities, availability of blood transfusion, proper management of shock. With liberalization of caesarean section, the rate of maternal morbidity and mortality is gradually on the decline.
A comparative study of misoprostol oral versus vaginal route for induction of labour
Authors: DebBarma Apratim Mohan , Baidya Jahar Lal , Ray Debasis
Published: April 2020

Background: Induction of labour at term is a common obstetric intervention. Prostaglandin E2 has been the agent of choice for pre-induction of cervical ripening for several decades. In recent time, prostaglandin E1 analogue (misoprostol) is a preferred new agent for pre-induction cervical ripening and labour induction owing to inexpensive, stable in room temperature, administrable through several routes. The ideal dose, route, and frequency of administration of misoprostol are still under investigation.Methods: A double blind parallel group placebo control randomized clinical trial was done in the department of obstetrics and gynecology of Agartala Govt. Medical College among 130 pregnant women those required induction of labour. In this clinical trial, the women were allocated by lottery to receive oral misoprostol (25 μg) and vaginal placebo (same dosage) or vaginal misoprostol (25 μg) and oral placebo (same dosage. Both active and placebo drug (25 mcg) were repeated at 4 hours. interval till the parturient reached active labour (not exceeding 5 doses). Both primary (induction delivery interval) and secondary outcomes (failed induction, vaginal/caesarean delivery rate, maternal and foetal complications) were statistically analyzed.Results: The mean induction delivery interval (primary outcome) differences were insignificant among both groups (oral versus vaginal). Success rate of induction (56.9% versus 75.4%), mean dosage (misoprostol 90.5 mcg versus 96 mcg) requirement, maternal and foetal complications was indifferent among two groups. The rate of vaginal delivery (within 24 hours of induction) was significantly higher when misoprostol was used through vaginal route. Caesarean section rate trends to be higher when misoprostol was administered orally.Conclusions: Low dose of misoprostol (25 mcg) offer an additional statistically significant clinical advantage in successful vaginal delivery when used vaginally.
Comparative study of induced and spontaneous labour in nulliparous women using modified WHO partograph
Authors: Yadav Kamlesh , Ranga Monika , Nama Ankur
Published: April 2020

Background: Induced or spontaneous labour has implication on the eventual mode of delivery and neonatal outcome. The aim of study is to compare mean duration of labour andmaterno-foetal outcome of induced versus spontaneous labour among nulliparous women using modified WHO partograph.Methods: The study was conducted in nulliparous women coming at term in active phase of labour (with cervical dilatation at least 4 cm) either spontaneous or induced, both labouring women were monitored using modified WHO partograph. Outcomes measures include requirement of augmentation of labour with oxytocin, mean duration of labour, eventual mode of delivery and the materno foetal outcome.Results: A total 100 women were compared in each group. There was no difference in mean age group, BMI, gestational age. More women had spontaneous vaginal delivery among those with spontaneous labour (76% versus 58%) (p=0.033). The mean duration of second stage of labour was significantly more in induced labour (16.25 minutes) than in spontaneous labour (14.60 minutes) (p=0.0212). The mean Apgar scores were comparable in two groups. Induced labour is comparable to spontaneous labour regarding fetomaternal outcomes but with increased rate of caesarean deliveries.Conclusions: Study concluded from our study that in spontaneous group mean duration of labour was less than induced group and most of the patient delivered vaginally. In induced group rate of caesarean was higher and requirement of oxytocin for labour augmentation was also more than spontaneous group. Maternal complications were also found more in induced group than spontaneous group whereas neonatal outcome was similar in both the groups. We observed in our study that induced labour can be a safe procedure among nulliparous women if labour is partographically monitored by WHO modified partograph.
Study of post caesarean section wound infection and microbiological epidemiology in tertiary care centre, Western Rajasthan, India
Authors: Sahay Nehal , Jhakhar Rekha
Published: April 2020

Background: Surgical site infection (SSI) following C-section is a common encountered problem and needs to be analysed. In this study we have determined the incidence, risk factors and common bacterial pathogens in surgical site infection (SSI) following C-section at a tertiary care centre.Methods: A hospital based prospective study conducted for a period of 6 months. Those women whose C-section was complicated by SSI within 5 days postoperatively were included in the study. Risk factors for SSI were identified and microbiological pattern was studied.Results: Out of 62 women whose C-section was complicated by SSI within 5 days post-operatively, during this study period post caesarian SSI incidence was 0.34%. In this study post C-section SSI found as high as 43.55%, in lower socio-economic status. Among all patients, un-booked were 62.90%, Referred patients were as high as 67.74%. SSI developed in 69.35% patients without preoperative antibiotic prophylaxis. C-section done in PROM in 64.50% and as an elective emergency 79.03%, blood transfusion needed in 59.68% and type of incision being transverse (Pfannenstiel) in 88.71%. Subcutaneous suture technique used in 75.81% and secondary healing occurred in 67.74%. Most common organism grown was CoNS (coagulase negative staphylococcus) 29.03% in SSI.Conclusions: To reduce SSI, the hospital infection control system and surgical site infection surveillance program has to be established. Knowing the prevalence and risk factors will help optimal precaution and standard surgical technique to reduce SSI, which causes increased hospital stay of patients.
Evaluation of swede score and reid score to improve the predictive value of colposcopy and its correlation with histology
Authors: Karya Urmila , Zehra Azme , Rani Anupam
Published: April 2020

Background: Cervical carcinoma is the second most common malignancy amongst women in India. It is regarded as a public health problem and a priority in cancer control programmes by the WHO. Colposcopy has proven to be very useful in identifying and guiding the biopsy of dysplastic lesion. To minimize inter-observer variation, colposcopic scoring system has been introduced.Methods: A prospective cross- sectional study including 250 women in whom the prevalence of different grades CIN was done. Co-relation of Pap (cytology) with colposcopy scoring system viz. Reid’s and Swede scores, has been made in this study. The two screening methods were compared and their statistical association with histological findings were analyzed.Results: Per speculum examination performed in 250 sexually active women with suspicious looking cervix, belonging to 25-60 years of age, with most common presenting complaints of pain abdomen (38.8%) followed by leucorrhoea, irregular cycles and Post coital bleed. Unhealthy cervix (49.2%) and persistent discharge (28%) were the most common indications for colposcopy. An assessment of both SWEDE score and Reid score as a function of histological findings was done, while Swede score of >5 showed slightly more sensitivity (100%) for diagnosing CIN1+ lesions, Reids score of >5 was more specific (100%) with a higher positive predictive value (100%) for diagnosing  CIN 1, 2, 3 and invasive cervical carcinoma. There was a marked positive association between Reid score and SWEDE score.Conclusions: The colposcopic scoring systems and histopathology showed significant compliance. Predictive accuracy of colposcopy increased with increasing severity of disease.
Comparative study of the efficacy of oral and intravenous maternal hydration in the management of third trimester oligohydramnios and it’s effect on maternal and foetal outcome
Authors: Khajotia Santosh , Naraniya Deepak , Meena Shubha
Published: April 2020

Background: Amniotic fluid is derived from maternal plasma in very early pregnancy by the 10th week of pregnancy. It forms an aquatic pond inside the amniotic cavity surrounding the fetus. It helps in fetal development. Aim of this study was to determine the impact of hydration therapy in patients complicated by oligohydramnios.Methods: This was a prospective randomized clinical trial conducted on 200 women.Results: Mean AFI in Group I was 4.47±0.90 cm before hydration therapy and 7.16±1.57 cm after hydration therapy with elevation by 60.18%, similarly mean AFI in Group II was 4.52±0.83 cm before hydration therapy and 7.48±1.56 cm after hydration therapy with elevation by 65.48%. However, on comparing the two groups elevations in mean AFI was found statistically insignificant (p >0.05).Conclusions: Oral hydration is non-invasive, low costing, does not exhaust the resource, convenient to the women with minimum side effects and can be done at home.
The efficacy of doppler indices in predicting the neontal outcome in term preeclamptic women with intrauterine growth restriction: an observational study in a tertiary care centre
Authors: Raj Krithika , R. Sheela S.
Published: April 2020

Background: Doppler flow velocimetry of the umbilical and fetal cerebral circulation is a non-invasive modality used to access the fetal well-being. Doppler is comparatively more specific and is potentially a useful tool in predicting adverse perinatal outcome in high risk cases. Objectives of this study were to evaluate the efficacy of Middle cerebral artery pulsatility index (MCA-PI), umbilical artery pulsatility index (UA-PI) and cerebroplacental ratio (CPR) doppler indices in assessment of fetal well-being. To document neonatal outcome in preeclamptic women with doppler changes.Methods: A retrospective observational study of term preeclamptic women with clinical IUGR admitting in labour room of RLJ Hospital from January 2019 to December 2019. All these women underwent Doppler study and were followed up till delivery.Results: A total 89 term preeclamptic women, 47.19% women had normal delivery, 52.81% lower segment caesarean section. 74.16 % delivered babies required NICU (neonatal ICU) care, 51.69 % babies had a longer duration of NICU care (more than 5 days). The perinatal complications like respiratory distress 8.99% low birth weight 39.33%, meconium stained 10.11%, still born 4.49% and perinatal asphyxia (6.06%). Women with abnormal MCA-PI 46.07% of cases, UA-PI in 40.45% and CPR 57.30%.Conclusions: It was observed that all three parameters CPR, MCA-PI and UA-PI when taken into account together are good utilities in predicting perinatal outcome.
Bakri postpartum balloon: an obstetrician’s armamentarium in managing post-partum haemorrhage
Authors: Sharma Arti , Bansal Neeta , Ramola Monika , Chaudhari Priyanka , Pant Suman , Panwar Neha
Published: April 2020

Background: Post-partum haemorrhage (PPH), an obstetric emergency that can complicate vaginal or cesarean deliveries and associated with serious complications. Guidelines for the management of PPH involve a stepwise escalation of pharmacological and eventual surgical approaches. In women who do not respond to uterotonics or medical treatment, a variety of procedures, such as arterial embolization, surgical ligation of the uterine arteries or obstetric hysterectomy, may be used. The Bakri balloon is an intrauterine device indicated to reduce or control PPH temporarily when conservative treatment is warranted. Here, we are presenting case series of primary atonic PPH and which were managed by Bakri Balloon Tamponade (BBT).Methods: This case series included five women with PPH managed by Bakri balloon as a conservative therapeutic option.Results: All five women were in age group between 23 years to 34 years. The causes of PPH were uterine atony, retained placenta and central placenta previa. The Bakri balloon was successful in controlling hemorrhage in all women (five of five) who did not respond to medical uterotonic treatment.Conclusions: Bakri balloon is a simple, easy to use and effective method for conservative management of acute PPH. This device reduces bleeding, shortens the hospital stay and avoids the need for more aggressive procedures.
Study of demography and clinical profile of ectopic pregnancies in a tertiary level hospital in Uttarakhand: a five year review
Authors: Nimonkar Shweta , Chaudhari Priyanka , Saxena Namrata , Gupta Vineeta , Tandon Archna , Singh Parul
Published: April 2020

Background: Ectopic pregnancy is a condition when a fertilized ovum is implanted outside the uterine cavity. Life threatening risk of rupture of ectopic pregnancy remains one of the important causes of maternal mortality in India. The aim of study is to analyse the clinical profile, associated risk factors, complications, treatment outcomes to improve maternal mortality and morbidity associated with ectopic pregnancy.Methods: It is a retrospective study conducted at Shri Guru Ram Rai Institute of Medical and Health Sciences from January 2015 to January 2020. A total of 182 patients diagnosed of Ectopic Pregnancy were analysed for clinical profile, risk factors, serology, ultrasound findings, complications, treatment offered and outcome.Results: During the study period of 5 years there were total 182 patients who were diagnosed of ectopic pregnancy showing the incidence of ectopic pregnancy in our hospital 1.4% of total number of deliveries. Majority of patients were in the age group of 25 to 30 years (43.95%). Mostly multiparous women (80.1%) had ectopic pregnancy. Majority of patients (56.1%) had no associated risk factors for ectopic pregnancy. Main presenting complain was abdominal pain in 58.8% of patients. Majority of patients (63.2%) had surgery as primary care which indicates delay in diagnosis and arrival at hospital especially in hilly region of Uttarakhand.Conclusions: Ectopic pregnancies need to be diagnosed timely to decrease maternal morbidities and mortalities.  Clinical signs and symptoms with serology (Serum beta hCG) and radiological findings helps to optimize treatment for potentially life-threatening condition.
Vulval carcinoma at the site of recent Bartholin gland excision: a rare case report
Authors: Kalpana B. , Balamurugan S. G. , Panda Soumya Ranjan
Published: April 2020

Around 2-7% of all vulvar cancers are represented by primary carcinomas of Bartholin gland. Here we are presenting such a rare case of carcinoma of Bartholin gland. 45/F P2L2 presented in our OPD with non-healing lesion in vulva for 2 months. She had history of Bartholin’s cyst excision (elsewhere), 2 months back (the exact time since when she is having the non-healing lesion in vulva). Diagnostic biopsy revealed it to be vulval squamous cell carcinoma. She was given two cycles of Neo adjuvant chemotherapy (Inj. Paclitaxel and Carboplatin). In view of better response to the treatment patient was planned for surgery. Patient underwent wide local excision with bilateral inguinofemoral lymphadenectomy. Although the majority of vulvar lesions are benign, especially in women younger than 50 years of age, any solid mass should be carefully evaluated for malignancy. Preferably biopsy of Bartholin gland should be considered if the patient is more than 40 years of age and should be mandatory in a menopausal woman.
Unruptured unilateral twin ectopic pregnancy: a rare case report
Authors: Gaur Nayanika , Goyal Piyush K. , Jha Manish
Published: April 2020

Unilateral twin ectopic pregnancy is a rare entity with an incidence of 1 in 125,000 pregnancies. This is a case of a 26-year-old primigravida with a spontaneous unilateral twin ectopic gestation, diagnosed on transvaginal ultrasound, treated laparoscopically by doing unilateral salpingectomy and confirmed with histopathology. The doubt for ectopic pregnancy was raised when the serum β-HCG level was constantly >1500 mIU/ml and serum progesterone level was <5 pg/ml and no intrauterine pregnancy was seen. On a follow-up scan, twin gestational sac was noted in right adnexa along with a large haemorrhagic cyst in the right ovary. On post-surgery follow-up, patient was found to have had complete recovery. This case report discusses the incidence and rarity, yet possibility of twin ectopic gestations, the need for early diagnosis and its management.
A rare case of perforating intrauterine contraceptive device
Authors: Singh Sarita , . Saima , . Jagriti , Dewan Rupali
Published: April 2020

The trends in the acceptability of contraceptives is globally shifting from permanent sterilisation to long acting reversible contraceptive (LARC). With the increasing use of IUCD, the knowledge of its common and rare complications has become pertinent. One of them is cervical perforation in which strings are mostly visible and hence it can be easily missed. Here we present a rare case of cervical perforation which was timely detected before it could have caused more damage. A patient complaining of IUCD associated pain should undergo thorough examination and a probability of perforation should be kept in differential diagnosis despite string visibility. A clinician has to be more vigilant about this rare complication to prevent damage to cervix and avoid unwanted pregnancy.
A rare presentation of invasive mole with an arterio-venous malformation: a case report
Authors: Dhillon Atmajit Singh , Pathak Vartika
Published: April 2020

Gestational trophoblastic disease comprises of various pathologies with hydatid form mole bring a common etiology. Emergency admissions of patients of gestational trophoblastic disease is very rare. Here we present a case report of an emergency admission of patient with hydatidiform mole and severe bleeding and then was managed for the same during the course of hospital stay.
They Treat. But Do They Actually Know? Evaluation of Knowledge Status about Management Guidelines of Avulsed Tooth among General Dental Practitioners of Agra – Mathura Region – A Cross-sectional Survey
Authors: Sahu Niketa , Gupta Sonal , Khanduja Ritu , Gupta Suneel Kumar , Mann Sneha , Devi Toijam Khema
Published: April 2020

Background: Avulsion is the most commonly occurring traumatic dental injury due to increased violence, road traffic accidents and partaking of children in contact sports and disregard to wear injury prevention devices. Replantation is the treatment of choice which is a very technique sensitive procedure and success depends on multiple factors. Aim: To evaluate knowledge status about the management guidelines of avulsed tooth among the general dental practitioners of Agra-Mathura region. Methodology: A questionnaire based cross-sectional survey was conducted among 184 general dental practitioners of Agra-Mathura region who were divided on the basis of educational qualification and practising experience. Statistical analysis was done. Chi square test was used for inter and intra group comparison. Results: There was presence of low knowledge level among the general dental practitioners. Significant difference was seen in the knowledge level among dentists based on educational qualification and practising experience in terms of handling of tooth after avulsion, socket preparation, splinting time period. Conclusion: Highly educated and more experience dentists had comparatively better knowledge still they lack information at multiple points. Current study indicates there is need to improve and update knowledge of dental practitioners on the management of avulsed tooth.
Comparison of Lip Print and Finger Print in Sex Determination of Salem Population
Authors: P. Suryagopan , Ramesh Maya , B. Sekar , Jacob Mathew , Arun Rajathi , Priyadharshini Indra
Published: April 2020

Background: In the field of forensic sciences, Practitioners face major problems in personal identification of humans. Lip prints and finger prints can serve as a significant tool for such identification and gender determination as they are unique and distinguishable to each individual. Aim: This study was aimed to evaluate the comparison of lip print and finger print pattern in Salem population for sex determination. Methods: This study comprises 200 lip prints (100 females and 100 males) which were randomly selected among Salem population with age ranging from 15 to 30 years and were collected with lip stick with the help of a cellophane tape on a white sheet, the same people were asked to press the cleaned fingers of right hand over ink-stained pad and the impression of inked finger was then transferred to the same white paper. Lip prints and Finger prints were examined with magnifying hand lens for pattern distribution - classified, recorded and analyzed. Results: Our study proved that the prevalent lip print in the males and females were Type III and type I respectively. The most prevalent finger print in the male was whorls Type and in female it was Loop type. There is statistically significant association between of these two parameters (p value=0.001) and thus these combinations can be implicated in detection of individuals. Conclusion: The use of lip and finger print patterns has been suggested to be consistent and reliable to suspect a fault. Correlation of these two parameters has significant association and thus the result of the present study can provide an additional tool in forensic science for gender determination.
A Customized Impression Technique for Highly Placed Mal-Aligned Implant for a Hybrid Over Denture Patient: A Case Report
Authors: Singhal Mukesh Kumar , Dandriyal Ramakant , Mendiratta Monal , Gangwar Sakshi
Published: April 2020

A hybrid implant denture is a fixed prosthesis over a metal framework and engaged by screws into the implant abutments. The anterior and posterior part of a mandibular hybrid denture is rigid on implants. Implant supported hybrid prosthesis provide satisfactory results on the mastication, esthetics and phonetics. This article describes a customized impression technique for highly mal aligned placed implants for hybrid implant denture. The total of five implants was present in the mandibular arch. Author advocates surveying of mal aligned implant analogue cast. The current technique depicts a customized resin impression tray with open border at two sites that concomitant at highly mal aligned implant position (canine region). Technique also uses the hard elastic chain for splinting of impression analogue. Final impression is recorded with single putty wash technique with polyvinyl siloxane elastomeric material. Although, technique is quite clinical sensitive. Asserting over this technique, it eliminates the use of transmucosal or multi unit abutments. This advocated technique is also economical for both clinician and patient. Impression was quite satisfactory.
Microplastic in the Arctic and Russian Far East Coastal Ground
Authors: Blinovskaya Ya.Yu. , Kulikova O.A. , Mazlova E.A. , Gavrilo M.V.
Published: April 2020

The first steps have been taken to study microplastics in the beach areas of the Arctic seas and the southern part of the Far East. Researches have shown that the average concentration in the areas studied is about 1 particle per kilogram of beach ground which is significantly lower than in other regions of the world. However due to the difficult access and irregular nature of the work an objective situation cannot be presented yet.
Problems of Ecology and Forest Protection in the Irkutsk Region
Authors: Rusetskaya G.D. , Baldanova L.P.
Published: April 2020

The main causes of drying out and loss of forest stands in the Irkutsk region are identified, the dynamics of losses of forest territories over a tenyear period from 2007 to 2017 is presented. It was revealed that the main causes affecting the state of forest plantations are fires, diseases of woody plants, in particular coniferous bacteriosis (bacterial dropsy of Siberian cedar pine (Pinus sibirica)) and dendrophage insects (Siberian cocoonworm (Dendrolimus superans Butler)). Suggestions have been made to improve the organization and conduct of forest protection and forestry activities.
Methodological Basis for Assessing the Level of Environmental Safety of Water Ecosystems in the Republic of Crimea
Authors: Volkova N.E. , Zakharov R.Yu.
Published: April 2020

A methodological approach to assessing the level of environmental safety of the water ecosystems of the Republic of Crimea is presented. Using the proposed methodology to assess the sustainability of the functioning of water ecosystems in the future will allow to rank river natural and technical systems on the level of environmental safety of their functioning, highlight the most vulnerable components of the water ecosystem and the main causes of increasing the likelihood of damage to both the water facility itself and its water users.
Nivel de conocimientos sobre anticoncepcion de emergencia en medicos generales que ejercen en Cartagena, Colombia
Authors: Monterrosa Castro Alvaro
Published: April 2020

La anticoncepción de emergencia es una importante estrategia de regulación de la fertilidad, para utilizar cuando se han tenido coitos sin protección y prevenir tanto el embarazo indeseado como el subsiguiente aborto en condiciones de riesgo. La anticoncepción de emergencia no es en definitiva un método abortivo. Para generar la expansión de la anticoncepción de emergencia hacia el acceso global, como sugiere el Consorcio sobre Anticoncepción de Emergencia, debe el cuerpo profesional de atención en salud sexual y reproductiva, especialmente el médico general, poseer claros y sólidos conocimientos, los cuales deben ser coherentes con su comprometimiento comunitario.Los resultados al evaluar 175 médicos generales escogidos al azar y que ejercen en la ciudad de Cartagena, Colombia, señalan que es regular el conocimiento concreto sobre anticoncepción de emergencia, muy por debajo de lo que debiese exigirse, y permiten inferir que no existe un suficiente y verdadero compromiso con su prescripción y divulgación. Es necesario adelantar amplias y masivas actividades y estrategias de educación médica continua, las cuales el mismo grupo investigado señaló estar interesado en recibir.
Diagnóstico prenatal de hepatoblastoma congénito: reporte de un caso
Authors: Luque Luz Stella , Pinzón Walter E. , Sarmiento Andrés
Published: April 2020

Presentamos un caso de diagnóstico prenatal de hepatoblastoma congénito. Se presentan los aspectos más relevantes acerca del diagnóstico ultrasonográfico de esta rara patología maligna. Se comentan aspectos relacionados con el diagnóstico diferencial, manejo obstétrico, pronóstico y seguimiento neonatal.
Factores asociados al papilomavirus humano en mujeres Mexicanas
Authors: González-Losa María del R. , Polanco-Marín Gerardo , Puerto-Solís Marylin , Murguía-Mesina Pedro
Published: April 2020

El objetivo de este estudio es determinar las variables epidemiológicas asociadas a la infección por papilomavirus humano en un grupo de mujeres mexicanas. En un estudio prospectivo, transversal y comparativo, se estudiaron 470 mujeres que acudieron para valoración citológica y colposcópica; previo al examen ginecológico se les realizó una entrevista en la cual se consignó la ficha de identidad, historia reproductiva, anticonceptiva, sexual, tabaquismo pasivo y activo. El diagnóstico de papilomavirus se realizó por citología y colposcopia. Las mujeres infectadas fueron más jóvenes y tuvieron menos embarazos y partos que las mujeres sanas. En el análisis multivariado la edad de las pacientes y la edad del primer embarazo resultaron ser factores protectores contra la infección. A diferencia de otras investigaciones, este estudio no encontró ninguna asociación entre la infección con papilomavirus y la conducta sexual.
КОЛЧЕДАННЫЕ МЕСТОРОЖДЕНИЯ ЭНСИМАТИЧЕСКИХ ОСТРОВНЫХ ДУГ КАЗАХСТАНА НА ПРИМЕРЕ МЕСТОРОЖДЕНИЯ АБЫЗ
Authors: Мазуров Алексей Карпович , Рудмин Максим Андреевич , Байболова Шынар Жуматаевна , Кряжева Татьяна Владимировна
Published: April 2020

Актуальность исследования определяется необходимостью освещения новых данных по формированию колчеданного оруденения (Au-Cu-Pb-Ag) в энсиматическихостровных дугах поздней стадии развития.Проведенные исследования показали, что перспективы энсиматическихостровных дуг полностью не исчерпаны. Цель: изучить петрологические, геохимические особенности пород и вещественный состав руд для уточнения прогнозно-поисковых критериев при прогнозировании и поисках колчеданного оруденения в энсиматическихостроводужныхгеологических образованиях. Методы исследования включали изучение состава горных пород и рудс использованием классического минералогического, петрографического и минераграфическогоанализов и сканирующей электронной микроскопии.Химический состав пород определялся с помощью силикатного анализа. Данные химического анализа были пересчитаны по кислородному методу Т. Барта для определения привноса и выноса химических элементов. Результаты.Колчеданные месторождения Казахстана в основном формировались в островодужной геодинамической обстановке. Островодужныепалеосистемы Казахстана подразделяются на энсиматические и энсиалические. С энсиалическимиостровными дугами связано формирование Рудноалтайского полиметаллического пояса. Месторождение Абыз связано с формированием энсиматической островной дуги поздней стадии развития.Островодужное основание заложено на океанической коре и представлено преимущественно осадочными породами: вулканомиктовыми и полимиктовыми песчаниками, конгломератами и алевролитами.Породы, слагающиеместорождение,подверглись интенсивному гидротермально-метасоматическому изменению, выразившемуся в пропилитизации и березитизации. В результате метасоматических процессов на месторождении было сформировано 13 рудных тел. Морфология рудных тел довольно сложная, формы линзовидные, линзовидно-пластовые. Основными минералами массивных колчеданных руд являются: халькопирит, пирит, сфалерит, галенит, блеклые руды, теллуриды (альтаит, раклиджит) и включения золота. Содержание серебра в золоте достигает 12,5%.
ПРИНЦИПЫ УСТОЙЧИВОГО РАЗВИТИЯ ГОРНОТЕХНИЧЕСКИХ СИСТЕМ В ПЕРЕХОДНЫЕ ПЕРИОДЫ
Authors: Бурмистров Константин Владимирович , Осинцев Никита Анатольевич
Published: April 2020

Актуальность исследования. Функционирование горнодобывающих предприятий в современных условиях характеризуется активным воздействием факторов внешней и внутренней среды. В условиях нестабильной внешней среды, при переходе от одного этапа разработки к другому, подсистемы горнодобывающих предприятий должны подчиняться цели обеспечения устойчивого функционирования предприятия – обеспечению выходных потоков с заданными параметрами. В этот период изменяется устойчивость горнотехнической системы, что оказывает влияние на состояние экономической и социальной подсистем горнодобывающих предприятий, а также на состояние окружающей среды, вызванное изменениями в параметрах технологии и технологических процессах. Это требует разработки новых подходов и принципов управления работой горнодобывающих предприятий, основанных на согласовании экономических целей с целями в области экологии и социального развития.  Цель: разработка концепции устойчивого развития горнотехнических систем в переходные периоды разработки месторождений на основе систематизации существующих принципов устойчивого развития в горнодобывающей отрасли. Объекты: горнодобывающее предприятие, горнотехническая система, система вскрытия карьера. Методы: обзор научной литературы, структурно функциональный анализ, системный анализ. Результаты. Обоснована ключевая роль системы вскрытия в структуре горнотехнической системы для обеспечения целей устойчивого развития горнодобывающих предприятий. Выполнена систематизация принципов устойчивого функционирования и развития горнодобывающих предприятий и его систем с выделением четырех групп принципов: общесистемные принципы управления, принципы развития горнодобывающих предприятий, принципы развития горнотехнической системы, принципы развития подсистем горнотехнической системы. В основу предлагаемой системы принципов положена идея последовательного преобразования подсистем горнотехнической системы на всех этапах проектирования и эксплуатации, учитывающая экономические, социальные и экологические аспекты с целью обеспечения заданных параметров функционирования горнодобывающих предприятий. Предложена концепция устойчивого развития горнотехнической системы в переходные периоды разработки. Использование предлагаемого подхода в период перехода от открытых горных работ к открыто-подземному способу разработки позволяет улучшить экономические, экологические и социальные показатели функционирования систем горнодобывающих предприятий.
As convenções jornalísticas e a verbo-visualidade do jornal impresso entre tensionamentos
Authors: Pereira Jácome Phellipy , Souza Leal Bruno
Published: April 2020

Neste artigo, discutimos a verbo-visualidade do jornal impresso, tendo como foco principal o papel comunicativo das convenções jornalísticas. Essa discussão se ancora numa noção ampliada de texto, buscando perceber seus aspectos configurantes e pragmáticos. As convenções se apresentam como um ponto de articulação entre padrões sedimentados de um fazer jornalístico, intimamente ligados às dinâmicas culturais e comunicacionais que situam produtos e processos historicamente, e os modos como cada mídia informativa emerge na regular singularidade de uma edição peculiar. Nessa perspectiva, a ideia de identidade de uma dada mídia informativa e mesmo das notícias que ela reporta adquire novos contornos, revelando uma qualidade fortemente performativa e em constante negociação.
STRATEGI ACADEMIC SELF-MANAGEMENT SISWA DALAM MENYELESAIKAN SEKOLAH SELAMA 2 (DUA) TAHUN DENGAN SISTEM KREDIT SEMESTER (SKS) (STUDI PADA SISWA KELAS XI SMA)
Authors: Reksiana  , Kamalia Ade
Published: April 2020

Penelitian ini disandarkan pada permasalahan terkait manajemen diri peserta didik yang kurang terorganisir, bermotivasi rendah, serta permasalahan minat belajar. Tujuan penelitian ini yaitu untuk menggambarkan keadaan yang sebenarnya tentang objek yang diteliti secara sistematis, aktual, akurat dan mendalam terkait fakta-fakta tentang strategi academic self-management siswa dalam belajar untuk menyelesaikan studi selama 2 (dua) tahun dalam program sistem kredit semester (SKS). Metode yang digunakan dalam penelitian ini adalah kualitatif dengan jenis analisis deskriptif. Teknik pengumpulan data yang digunakan berupa observasi partisipatif, wawancara dan dokumentasi. Sedangkan teknik analisis data menggunakan model Miles dan Huberman. Hasil penelitian menunjukkan bahwa self-talk (berbicara dengan diri sendiri) merupakan salah satu aspek yang paling berkontibusi dalam memberikan motivasi kepada siswa. Aspek lain yang juga berkontribusi dalam memotivasi siswa seperti adalah pemilihan metode belajar sesuai dengan gaya belajar, penggunaan waktu berdasarkan skala prioritas, deadline, kerumitan tugas, lingkungan fisik dan sosial serta kemampuan peserta didik dalam mengevaluasi diri untuk tujuan pembelajaran.
PENGEMBANGAN RENCANA PELAKSANAAN PEMBELAJARAN (RPP) TEMATIK BERBASIS KARAKTER
Authors: Hanum Fathia Fairuza , Suprayekti Suprayekti
Published: April 2020

Penguatan Pendidikan Karakter (PPK) merupakan kebijakan pendidikan yang bertujuan untuk mengimplementasikan nilai religiusitas, nasionalisme, kemandirian, gotong royong, dan integritas. Agar dapat terimplementasi di dalam pembelajaran diperlukan pengembangan Rencana Pelaksanaan Pembelajaran (RPP) yang terintegrasi dengan nilai-nilai tersebut. Tujuan penelitian ini adalah untuk menghasilkan prototipe produk RPP tematik yang dikhususkan untuk siswa kelas 2 SD. Penelitian ini dilakukan dengan metode Research & Development (R&D) yang disederhanakan. Penelitian dilaksanakan dari Bulan Juni sampai Oktober 2019, bertempat di SD Muhammadiyah 24 Jakarta Timur. Validasi produk dilakukan oleh ahli dan kelompok kecil. Hasil penelitian secara umum menunjukkan bahwa kualitas prototipe yang dihasilkan berdasarkan validasi dari ahli desain pembelajaran dan ahli materi adalah sebesar 76% dan 98%. Sedangkan berdasarkan hasil ujicoba skala kecil kualitas yang didapatkan adalah 90%. Hasil tersebut menunjukkan bahwa produk prototipe RPP tematik yang dikembangkan dapat diterapkan dalam proses pembelajaran pada siswa kelas 2 SD sehingga dapat memberikan dampak pengiring yang akan menghasilkan karakter yang sesuai dengan PPK. Dan sebaiknya ada penelitian lanjutan yang akan mengembangkan produk ini menjadi lebih sempurna.
Program Kemitraan Universitas bagi Pengurus Kelompok Tani Sumber Rejeki III untuk Mengelola Administrasi Keuangan Syariah
Authors: Widyanto R Arri , Sunarni Sunarni , Triyanto Andi
Published: April 2020

Sumber Rejeki III Farmers Group is an organization that accommodates farmers in Turen, Kradenan Village. Currently there are 45 active members of farmer groups, all of whom are from Turen. The management of the average main job is farmers who are on average 48 years old. The level of education of the management of high school and equivalent farmer groups. The level of mastery of computer operations 0% of all managers. The problem that occurs in this farmer group is that there are no administrators who can operate the computer, so the administration has not been well organized. All documents are written manually using separate books and note papers. Especially in making reports of Lembaga Keuangan Mikro(LKM)  that must be reported every month to farmer groups, they must collect from many records and not infrequently there are records that are scattered or lost which cause reports especially financial statements to be invalid. The objectives of this partnership program are: (a) Giving skills to operate computers, especially office application programs for farmer group administrators. (b) Giving skills in making invitations automatically using a mail merge facility. (c). Improve ability in recording and making financial reports. The methods used: (a) the preparation stage, (b) the implementation stage, (c) the evaluation phase and (d) preparing the report. The results of this activity, the average level of mastery of computer utilization for administrative activities are as follows: Mastering (0.78%) and Self-mastering (0.22%), Output of PKU is increasing the ability of partners to use computer applications for administration to 70% of the original target of 50%. In addition, savings and loan activities for these farmer groups' LKM use the sharia accounting system
Peningkatan Efisiensi Kerja Guru Melalui Pembuatan Aplikasi Rapor Berbasis Komputer
Authors: Widodo Romy Budhi , Subianto Mochamad , Imelda Grace
Published: April 2020

The domain of the activity is technology for the society whereas the focus is practical computer science for the society. The background of our activity is based on the needs of YPK junior high school in Malang city, Indonesia. The school need to develop computer-based school report card and also daily grade card for teachers. The method for software/application development is spiral model which consist of the cycle of system identification, risk analysis, and enhancement of the prototype to be an operational prototype. Evaluation of the product was based on the Computer System Usability Questionnaire (CSUQ) from IBM. The CSUQ using 5 scale of Likert scale contains three categories: 1) system usefulness (SYSUSE), 2) information quality (INFOQUAL), and 3) interface quality (INTERQUAL). The mean rank’s result in order from the greatest to the lowest is SYSUSE, INTERQUAL, and INFOQUAL, respectively. It was reported that SYSUSE category was superior to INFOQUAL (U = 3369.5, p = 0.0005). Overall, the user satisfaction score is 78.4%, which is in the “worthy” category
Pemberdayaan Usaha Mikro Kecil Aksesoris Aquarium Desa Tamanharjo Singosari Kabupaten Malang
Authors: Lutviana Rizky , Kurniawati Maris
Published: April 2020

This community service program aimed at empowering H-Fish aquarium Assesories small business to become independent and developed. A business may be considered as developed if it meets criteria such as increasing revenue, increasing product variation, efficient production, good packaging, and good management system that meets standard. In order to achieve that goal, the researcher gave sequencial trainings including training in operating and maintenance the machine production, training in packaging product and label design, training business management that meets standard and training in product variation. Besides, the researcher also helped to improve product marketing including renovating production side and building showroom to display the product to attract potential buyers. The results of this community service were increasing revenue since the product variation is increasing and the packaging was also improved to be more attractive. H-Fish Aquarium Assesories developed well because of efficient production, good business management, and wider marketing.