bluuebunny/crossref_metadata_2025 huggingface dataset:
The Experience of Primary Healthcare Nurses during the COVID-19 Pandemic in Lebanon
Authors: Zahwe Oussama , Farhat Ali , Karawni Mahdi
Published: January 2023

The 2019 coronavirus outbreak was a worldwide event, and nurses had little time to prepare before being flooded with high-acuity patients and navigating new care plans. Nurses working in primary care at Tyre Hospitals and Medical Centers were invited to take part in an extremely cross-sectional online survey via social media and professional organizations. The survey tool was composed of demographic, and questions on the nurses’ employment and work roles. A total of 196 participated in the study. Nearly half of respondents (n = 88; 44.9%) reported either increased hours of employment, threatened termination, or actual termination of employment. Just over half of respondents (59.7%) feel well supported in their clinical role by their employer. While most respondents felt that they had sufficient knowledge about COVID-19, they expressed worry about work-related risks to themselves and their family members. 65.8% of respondents perceived that the support provided in their workplace was better than before the pandemic. The present paper represents the first study of primary healthcare nurses’ experiences during the COVID-19 pandemic in Lebanon. The study findings revealed a concerning level of support for primary healthcare nursing employment based on the number of participants.
Defining categories of Fintechs: A Categorization Proposal Based on Literature and Empirical Data
Authors: Caciatori Jr. Itamir , Mussi Szabo Cherobim Ana Paula
Published: January 2023

Purpose – The analysis of the competitive impact of FinTechs requires the standardization of their categories to compare their products and services with the already delivered by incumbent banks. In this study, we address the problem of the multiplicity of FinTechs categories and provide a solution using content and cluster analysis.Theoretical framework – The literature about FinTechs. In our bibliographical research, we do not find works aiming to present a standard definition of categories of FinTechs. This type of work is almost nonexistent and categorization of FinTechs is defined as a “blurry issue”.Design/methodology/approach – In this study, we address the problem of the multiplicity of FinTechs categories and provide a solution using content analysis, cluster analysis, and the software Gephi.Findings – The result is a model comprised of nine FinTechs categories: Payments and Transfers; Exchange; Lending; Insurance; Investments; Advice; B2B; Digital Banks; and Others. We also elaborate a portfolio with 157 products and services offered by Brazilian incumbent banks, which allows the comparison between these two types of companies.Originality/value – The main contribution is the use of objective criteria and existing literature, as well as Gephi software, to build categories of FinTechs analysis, an emerging theme in financial market studies.
HEMODYNAMICS EFFECT OF BUPIVACAINE AND LEVOBUPIVACAINE IN PAEDIATRIC ABDOMINAL SURGERIES
Authors: Digraskar Vinod Devidasrao , Singh Prem Raj , Xess Sukriti , Jain Akansha , Kashikar Dnyanesh
Published: January 2023

Regional analgesia features a prime role within the multimodal analgesia approach for surgical pain management. currently each day it's common apply of using transverses abdominis plane block (TAP Block) with numerous sorts of native anaesthetics and adjuvants, as a multimodal pain relieving remedy used worldwide for intra and postoperative pain management in several surgeries. However, only a few studies are done wherever hemodyanamics effects when bupivacaine versus levobupivacaine have compared. Aim of this study to examine the consequences of bupivacaine vs levobupivacaine in patients undergoing lower abdominal surgeries and their effects on hemodynamics ( the blood pressure, HR, and SpO2). Method: A randomised double-blind management study conducted when approval from IEC Ref. code-92nd IIB Thesis / P4 . The study has fifty patients, with ASA I – II physical status, as well as each sex and 2-10 years cluster age and who set up for abdominal surgery notably lower abdominal . 25 patients set in every group and every which way allotted: cluster Bupiva and Levobupiva . All patients were well well-read regarding the procedure, drugs, and effects of drugs, and untoward complications. well-read written consent was taken from each patient before involving them within the study. primary objective is to examine the impact of those medicine on Blood pressure, HR, and SPO2 & Secondary objective was to check rescue physiological condition reduction within the surgical period. After the comparison between these 2 clusters, The mean SBP of group Bupiva was found below that of group Levobupiva . and located to be important at fifteen min, one hour, a pair of hr, and four hr and insignificant at baseline zero min, thirty min, half dozen hr (p=0.092), twelve hr, eighteen hr, and twenty four h.differences is insignificant in comparison the DBP at any purpose of your time from baseline to 24 hr. On comparing the center rate, variations were found insignificant from baseline (p = 0.897), 0 min (p = 0.651), 30 min (p = 0.096), 1hr (p = 0.192), 2 hr (p=0.390), four hour (p=0.525), half dozen hr (p=0.469), twelve hr (p=0.443), eighteen hr (p=0.288) to twenty four hr (p=0. 390) except at fifteen min (p=0.010) that was the mean pulse rate of cluster Bupiva is over that of group Levobupiva at one,5 min. On comparison the SPO2differences were insignificant at baseline (p = 0.620), 15 min (p = 0.108), thirty min (p=0.353), 1 hr (p = 0.789), 2 hr (p = 0.364), 4 hr (p = 0.292) and 6 hr (p = 0. 198) however important at 0 min (p = 0.002), 12hr (p = 0.012), 18hr (p = 0.002) and24 hr (p = 0.028) wherever the mean SPO2 of cluster Bupiva was abundant below the group Levobupiva. Stable hemodynamics for a extended period were provided by Levobupivacaine as compared to Bupivacaine.
DETERMINATION OF SEX FROM FOOTPRINT DIMENSIONS AMONG NUPE ETHNIC GROUP IN MINNA NIGER STATE
Authors: Alabi Ade Stephen , Aniyikaye Aishat , Odunnaike Opeyemi Olaoluwa , Adunmo Godwin Olawoyin
Published: January 2023

Determination of personal identity is a basic and pivotal step in forensic investigations and medico legal practices. In anthropological cases, forensic identification is generally carried out through examination of the body or the remains for prints from the body. Thus, the footprint becomes an invaluable index of identification particularly when the whole body is very badly mutilated. This study was carried out to determine the relationship between footprint dimensions and sex among individuals of Nupe ethnic group of Niger State. Sample size of four hundred and twenty one (421) subjects, two hundred and eighty three (283) males and one hundred and thirty eight (138) females were used in this study. The footprints were gotten by placing the volunteers' foot on the ink pad and it was then transferred on anA4 paper, where the footprint dimensions were later measured with a meter rule. The results of this study show that sex differences were highly significant using toe lengths and breadth (P≤ 0.01) but the footprint indices shows no statistical significance. Footprint dimension is sexually dimorphic. Footprint dimensions can be used to determine sex in addition to or in absence of skeletons such as long bones and skull. It can be applied in forensics for medico legal cases, shoe designing, fashion design and industrial design to optimize products.
ASSOCIATION OF γ-GLUTAMYLTRANSFERASES (GGT) WITH AND WITHOUT HYPERTENSIVE RETINOPATHY IN NORTH INDIAN POPULATION
Authors: Nigam Bharti , Chaturvedi Ashutosh , Sharma Kanika
Published: January 2023

γ-Glutamyltransferase (GGT) has been extensively studied because it mediates the intracellular uptake of extracellular glutathione, a key component of the antioxidant mechanism. The most common modifiable risk factor for cardiovascular disease is hypertension, and has been found to be associated with serum GGT levels, especially in middle-aged and older adults. Serum GGT is involved in the pathogenesis of hypertension. A case-control study was conducted for 24 months with patients with pre-diagnosed hypertension in the ophthalmology department. Patients were classified into two groups, group 1 with 50 patients previously diagnosed hypertensive patients aged 40 years without hypertensive retinopathy and group 2 (100 patients) with had hypertensive retinopathy. Serum gamma-glutamyl- transferase was measured using the CORAL Colorimetric Assay Kit. Majority of patients were aged between 40 to 59 years and were females. SBP, DBP and MAP significantly increased in group 2 when compared with group 1. Majority of group 2 patients had GGT levels >40 U/l (89.0%), while the majority of group 1 had her GGT levels less than <40 U/L (62.0%).According to our study, GGT was significantly increased in patients with high blood pressure (SBPand DBP) and a family history of hypertension.
STUDY OF PAPILLOEDEMA AND ITS CAUSATIVE FACTORS IN A TERTIARY CARE HOSPITAL
Authors: Singh Luxmi , Nigam Bharti , Shahaan Syed , Saxena Naman
Published: January 2023

To study the etiology of papilloedema in north indian population. Our hospital based retrospective study enrolled 50 patients of papilloedema, who fullfilled our inclusion criteria. Demographic details, chief complains and detailed history was taken from all the patients. All the patients underwent blood pressure measurement by a mercury sphygmomanometer, Visual Acuity testing, Slitlamp Biomicroscopy, IOP measurement, Fundus examination. Fundus photographs were obtained using a fundus camera. Other investigations included B-scan, MRI, MRV, CT and required blood investigations were done wherever necessary. Although papilloedema occured in a vast variety of age group but maximum patients (32%) were from the age group of >18-31 years and males (64%) were more affected than females according to our study. 66% of the patients had good vision with papilloedema. In our study all the patients had bilateral papilloedema and 54% of patients were diagnosed with early papilloedema. Idiopathic Intracranial Hypertension was the main etiology for papilloedema. In this study we concluded IIH (a diagnosis of exclusion) as the most common underlying etiology for papilloedema.
A CLINICOHAEMATOLOGICAL PROFILE OF ADVERSE TRANSFUSION REACTIONS AND ITS ASSOCIATION WITH BLOOD COMPONENTS
Authors: Salmani Adil , Bhardwaj Aparna , Ahmed Saqib , Raturi Gaurav
Published: January 2023

Different blood components are associated with various types of adverse transfusion reactions and are linked to several factors including the number, rate and volume of transfusions. The given study was conducted to study the relationship between various transfusion reactions and its causative factors. This study was a prospective study of eighteen months on all patients who were recipient of a blood transfusion and blood components including various adverse reactions and events related to transfusion. These were correlated with tests for compatibility including general blood picture ,tests for haemolysis ,hematuria and haemoglobinuria, Coombs Test (Direct and Indirect), culture along with relevant clinical details of the patient. Out of a total of 31451 units of blood issued, 47 adverse transfusion reactions were noted with a maximum number in the age group of > 18 years (87.3%) with M: F being 1.6: 1 .0.24% of adverse transfusion reactions were by Packed red blood cell (PRBCs) transfusion and mostly were immediate transfusion with a mean volume of 100 ml and mean time of 20 minutes. Febrile Non Hemolytic Transfusion Reaction (FNHTR) was the commonest Adverse Transfusion Reaction (ATR)(0.128%) with 2 cases positive for Direct Coombs Test. A thorough serological and immunological examination and the addition of methods like buffy coat reduction and leucocyte filtration help in reducing the incidences of hemolytic transfusion reactions and transmitted infections and establishing a hemovigilance system help in the attainment of the goal of safe transfusion.
THERAPEUTIC USES OF BUTEA MONOSPERMA
Authors: Singh Kalpana , Srivastava Arvind Kumar
Published: January 2023

New synthetic drugs have many side effects on health as compared to the traditional herbs used in the past.The use of medicinal plants have been en established source for a relief from illness which can be traced back over five millennia. Antibiotics are one of the life saving weapons for humans but over the past few decades these health benefits are under threat as antibiotics have become less effective and also create toxic after effects affecting human life more. The well-known medicinal herb Butea monosperma is a moderately Sizeable deciduous tree and is widely dispersed in Asian hemispheres, Burma and Sri Lanka. From time to time it has been used in traditional medicinal practices. It has been mentioned in ayurveda for medicinal uses and mythological references, also The population's health care system continues to be heavily influenced by traditional medical practises, homoeopathy, and folklore. Rural and tribal people utilise the herb extensively to treat a variety of ailments. It is known in many languages apart from its botanical name. It is called Flame of forest, Dhak, Palash etc. It has been used to treat a variety of illnesses including cancer, diabetes, dysentery, fever, jaundice, diarrhoea, and jaundice, among others. A great variety of phytochemicals, primarily flavonoids, lactones, diterpenoids, phytosterols, etc., are present in the plant's aerial portion. The need for new antimicrobial compounds from alternative sources has arisen as a result of the development of drug resistance in human infections against routinely used antibiotics. Finding possible novel chemicals for therapeutic purposes requires screening medicinal plants for antibacterial and phytochemical properties .
MATERNAL HEALTH SITUATION IN UTTAR PRADESH, INDIA
Authors: Faridi Samrah Butool
Published: January 2023

Health of children and their mothers is a vital aspect of a society's longterm development. Unfortunately, around half of all mothers and over 10 million children die due to preventable causes. Data from a current National Family Health survey (NFHS) was utilized and compared with the previous data of the surveys conducted at national level. The maternal mortality ratio in India has decreased to 113 per 100,000 live births, according to a report released by the WHO. Only 51.6% women reported three or more ANC visits where anaemia is still found among 35.4% women. Although 88% of women delivered in a health facility whereas only 5 7.5 % mothers received postnatal care within two months. The Maternal Mortality Ratio (MMR) in Uttar Pradesh is remains high due to a lack of utilisation of available maternal and child health services, putting the health of mother and children at risk. Hence, to improve the health status, evidence-based policies with grass root level programme planning are required.
ANGIOKERATOMA: A RARE MANIFESTATION
Authors: Zehra Andleeb , Tandon Nishi , Chaudhary Reeta , Shukla Shivangi , Lal Nirupma
Published: January 2023

Angiokeratoma shows dilatation of capillaries in the upper dermis and it also shows some epidermal changes, like- hyperkeratosis, papillomatosis, and thickening of epidermis or acanthosis .Clinical presentation of angiokeratoma includes plaques over the skin of lower limbs, mostly on the buttocks or thigh. It is usually identified clinically but a definitive diagnosis is made only on histopathological examination.Adeeper biopsy of the lesion is empirically essential to make a concrete diagnosis as the characteristic changes seen in angiokeratoma, are limited to superficial dermis. Our case report has a 24 years old female presenting with unilateral, linear, bluish-black verrucous plaque on the back of left elbow.
TWO INTERESTING CASES OF FILARIASIS AT UNCOMMON SITES
Authors: Fatima Ambreen , Khanduri Sachin , Khan Zaara , Ansari Danish , Dhingra Vibhor , Jamal Hamza
Published: January 2023

Filariasis is a condition resulting from filarial parasites that affects both humans and animals.There are several hundreds of filarial parasites which have been mentioned in medical literature, out of which only eight species are known to cause natural infections in humans. Repeated episodes of inflammation and lymphedema cause lymphatic damage, persistent edema, and elephantiasis of the legs, arms, scrotum, vulva, and breasts. We have reported two cases of filariasis at unusual sites.
DELAYED PRESENTATION OF POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME IN POSTPARTUM PERIOD
Authors: Singh Kajal , Ahmad Ayesha , Gupta Uma , Nishad Suman
Published: January 2023

Posterior reversible encephalopathy syndrome (PRES) is an uncommon neurological entity which presents with diverse neurological symptoms ranging from headache, seizure, visual symptoms with altered consciousness and focal signs. The hallmark of this condition is its reversibility. The etiopathogenesis is attributed to vasogenic cerebral oedema seen in occipital and parietal lobes of brain. We hereby present this case of a multiparous lady presenting with altered sensorium postpartum. Characteristic findings on imaging helped us to form the diagnosis of PRES in this patient.
Bacterias y hongos utilizados en la biodegradación de hidrocarburos: Una Revisión de literatura y Análisis Bibliométrico.
Authors: Rabelo Florez Roger Alberto
Published: January 2023

Introducción: El uso de los hidrocarburos y sus derivados, han generado un problema de contaminación ambiental. Los estudios más actuales sugieren una solución a esta situación, basada en la degradación microbiológica o biotransformación, usando cultivos microbianos axénico. Objetivo: Desarrollar un mapeo sistemático de la literatura científica sobre las investigaciones, acerca de las bacterias y hongos en la biodegradación de Hidrocarburos. Metodología: Se realizó la exploración, clasificación, verificación y estudio de los documentos con las respectivas directrices de indagación en relación al propósito de esta investigación. Los documentos obtenidos de WoS y Scopus se fusionaron y se eliminaron las réplicas, para esto se utilizó el software R studio. Posteriormente, se desarrolló un estudio de origen, referente teórico, estudio bibliométrico y de redes sobre bacterias y hongos en la biodegradación de Hidrocarburos. Resultados: La búsqueda arrojó un total de 424 registros. Se logró evidenciar que la temática ha tenido un aumento significativo a través de los años, principalmente a partir del año 2015, teniendo un incremento del 51.9% y con una tasa de aumento anual del 10.41%. El país con mayor producción científica es China con 67 publicaciones. Según los documentos científicos revisados hasta el 2021, este es el primer estudio de revisión sistémico sobre BHBH, que ha utilizado la aplicación R studio para analizar la productividad bibliográfica en este tema. Conclusión: Algunos de las bacterias nativos que biodegradan hidrocarburos son Gordonia, Brevibacterium, Dietzia, Burkholderia, Pseudomonas aeruginosa. Para hongos son Aspergillus, Penicillium, Fusarium. Para levaduras son Candida, Yarrowia y Pichia.
FORMATION OF THE ANTHROPOMETRICAL STATUS DURINFG PHYSICAL DEVELOPMENT PHASE
Authors: Fedorchuk S. M. , Kupchak R. M.
Published: January 2023

In this work we’ve defined one-measured statistical analyses of antropometrical parameters of men and women (age of 7-18 y. old). These data were defined on basis of growth and differentiation of the most informative of metrical signs including physical development. In order to determine the most informative metrical parameters belonging to people while growth phase, 10 examples of absolute size, body mass and 3 indexes have been examined among people who live in Western region of Ukraine.Together with public health services, for purposes of preventive supervision 360 male and female persons aged 7-18 years have been examined (i.e. students of secondary school). Anthropometrical parameters were determined according to the accepted medical anthropology’ methodology: trunk length, shoulders’ breadth, pelvis breadth, longitudinal head diameter, the most diametrical head diameter; head, armlet, thigh and shin circumference; body mass. Indexes were figured out according to trunk length(IRLT), shoulders’ breadth(IRBS) and pelvis. These parameters formed %(percentage) of correlation between corresponding proportions and height.Analysis of indications system which marks the anthropometrical status is enough to be able to determine (by means of the factorial criterion of sex) the index of relative trunk length at the age of 7, 13, 14, 15, 17, 18 years (Р<0,01 – 0,001). This analysis also helped to prove the comparison of all total indexes while second childhood phase (Р>0,05) and to determine the importance of sex trend in antroph-amorphous status formation at the age periods of 13-16 and 17-18 years: according to the index of pelvis breadth – 12, 13 years (Р<0,05),14, 15 years (Р<0,001) and index of the relative shoulders’ breadth - 15, 17, 18 years (Р<0,01 – 0,001).While adolescence, particularly at the age of 16 in female, more rapid body growth in height in comparison with trunk length is registered. It causes the decrease in IRLT indexes from 30,0% while childhood up to 27,5% at the age period of 13-18 years. On the contrary, IRBS index increases from 21,0% (childhood) to 22,0% (adolescence) and up to 23,5% (teenagers) in maleand from 20,6% to 21,3%and 22,5% in female persons in accordance with growth impairment.On the basis ofanthropometrical parameters’ indexes in male and female persons and taking into consideration their annual age appliance while growth phase, charts of the most veritable metrical parameters have been formed.
SUICIDE WITH SIMULATED GUNSHOT WOUNDS
Authors: Danyliuk Mykhailo , Zozulia Vitalii , Siukaiev V. , Ghanskiy Oleksandr , Lesyk Volodymyr
Published: January 2023

Given a case of suicide using a device for slaughtering cattle, limitirovanie gunshot damage to the skull. Despite versent the many facets of the problem of firearm injuries, its execution is judicial-medical examination continuesto be one of the most difficult.An integrated approach to the examination of gunshot injuries to the additional medical and forensic studies and a series of experimental shots is optimal for the objective of addressing issues relating to distance from which the shot was made.
FORENSIC-MEDICAL ESTIMATION OF THE NON-LETHAL TRAUMATIC BRAIN INJURY OF VICTIMS, WHO WERE TREATED IN MEDICAL INSTITUTIONS
Authors: Pletenetska Alina
Published: January 2023

Considering the high prevalence of traumatic brain injury in forensic practice, the article presents data from forensic examinations of victims in such cases, the main defects of doctors neurologists at diagnosis “traumatic brain injury” was described, that can help forensic experts in correct evaluation of traumatic brain injury.
WORK OPTIMIZATION OF INTER-DISTRICT OFFICES IN STRUCTURE OF CHERNIGIV REGIONAL BUREAU OF FORENSIC MEDICAL EXAMINATION
Authors: Potapenko Ihor
Published: January 2023

In this article we adduce the results at structure reforming of the interdistrict offices “Chernigiv Regional Bureau of Forensic Medical Examination”, which was due to the lack of specialists, lack of funding, imperfect material and technical basis and are aimed at improving the quality of forensic medical service of Chernigiv region. The indicated reformation does not conflict the project ‘of perspective plan of forming territorial communities of the Chernigiv area and “Methodology of forming solvent territorial communities” which was ratified on the session of the Chernigiv regional council at 19.06.2015. The main result of these reforms has become the increased efficiency of all divisions “Chernigiv Regional Bureau of Forensic Medical Examination“.
AS VÍSCERAS DA UNIVERSIDADE CONTEMPORÂNEA
Authors: Ferreira da Silva Camila , De Macedo Lopes Rodrigo
Published: January 2023

Resenha da obra "The Good University: what universities actually do and why it’s time for radical change", da socióloga australiana Raewyn Connell, publicada em 2019 em Londres pela Editora Zed Books Ltd.
Mutatsionnyye osnovy formirovaniya ustoychivosti k meropenemu u Pseudomonas aeruginosa
Authors: Чеботарь И. В. , Бочарова Ю. А. , Чаплин А. В. , Савинова Т. А. , Василиадис Ю. А. , Маянский Н. А.
Published: January 2023

Rezistentnyye k karbapenemam shtammy Pseudomonas aeruginosa rastsenivayut v kachestve kriticheski opasnykh patogenov pervogo urovnya prioriteta. Rasshifrovka mekhanizmov formirovaniya ustoychivosti k karbapenemam yavlyayetsya aktual'noy zadachey sovremennoy meditsinskoy nauki. Tsel'yu raboty bylo opisat' raznoobraziye i zakrepleniye mutatsiy, assotsiirovannykh s formirovaniyem karbapenemrezistentnosti v protsesse adaptatsii P. aeruginosa k povyshayushchimsya kontsentratsiyam meropenema. Ob"yektami issledovaniya byli izolyaty P. aeruginosa, poluchennyye pri roste referentnogo shtamma P. aeruginosa ATCC 27853 v gradiyente vozrastayushchikh kontsentratsiy meropenema. Otsenku chuvstvitel'nosti izolyatov k meropenemu vypolnyali pri pomoshchi ye-testov (epsilometricheskiy metod) s meropenemom i pri pomoshchi metoda dilyutsii antibiotika v agare. Genomy izolyatov byli sekvenirovany na polnogenomnom sekvenatore MGISEQ-2000. Poluchennyye rezul'taty pokazali, chto formirovaniye vysokikh urovney rezistentnosti k meropenemu u P. aeruginosa v eksperimente proiskhodit v korotkiye sroki (6 sutok). Evolyutsiya rezistentnosti sopryazhena s protsessom klonirovaniya, pri kotorom proiskhodit vozniknoveniye mnozhestva klonov s razlichnymi genotipami. Osnovoy klonirovaniya yavlyayetsya mutagenez, v kotoryy vovlecheny 11 genov, vklyuchaya oprD, pbuE, nalD, nalC, spoT, mlaA, mexD, mexR, oprM, mraY, pbp3. Chast' obrazovavshikhsya klonov, nezavisimo ot urovnya ikh rezistentnosti k meropenemu, ne poluchayut progressivnogo razvitiya i vytesnyayutsya boleye uspeshnymi klonami.
Effektivnost' favipiravira i molnupiravira protiv novykh variantov SARS-CoV-2 v organizme in vitro i in vivo
Authors: Синявин А. Э. , Руссу Л. И. , Васина Д. В. , Шидловская Е. В. , Кузнецова Н. А. , Гущин В. А. , Гинцбург А. Л.
Published: January 2023

Pandemiya zabolevaniy COVID-19 ostayetsya ser'yeznoy problemoy obshchestvennogo zdravookhraneniya, kotoraya privodit k sotnyam millionov sluchayev zabolevaniya i millionov letal'nykh iskhodov. Po vsemu miru aktivno idut razrabotki i issledovaniya osobykh ingibitorov SARS-CoV-2 dlya lecheniya dannoy infektsii. Takiye preparaty, kak favipiravir i molnupiravir, proyavlyayutsya isklyuchitel'noy protivovirusnoy aktivnost'yu v otnoshenii SARS-CoV-2, uzhe lechashchikhsya u patsiyentov. Odnako imeyutsya ogranichennyye dannyye ob ikh effektivnosti, osobenno v otnoshenii novykh geneticheskikh variantov vozbuditelya COVID-19. Tsel'yu issledovaniya bylo izucheniye modeley protivovirusnogo effekta preparatov s ispol'zovaniyem eksperimental'noy infektsii SARS-CoV-2 na kul'ture kletok Vero E6 in vitro i zhivotnykh modelyakh s ispol'zovaniyem amerikanskikh khomyachkov. Ustanovleno, chto molnupiravir imeyet vyrazhennoye ingibiruyushcheye deystviye v otnoshenii razlichnykh variantov virusa SARS-CoV-2 so znacheniyami IC50 ot 16,51 do 7,88 mkM in vitro i tyazhelyy infektsionnyy titr virusa legkikh zhivotnykh na ~1,5 Log10 in vivo, v to vremya kak favipiravir proyavlyayet boleye nizkuyu aktivnost' i vyrazhennuyu toksichnost'. Polucheniye rezul'tatov primeneniya tselevykh issledovaniy v primenenii podbora dozirovok i kratnosti.
Antropologia: um desafio para a educação e o desenvolvimento humano
Authors: Wulf Christoph
Published: January 2023

Objetiva contribuir para a análise da relação entre antropologia, educação e desenvolvimento humano e aborda amplos panoramas do conceito de antropologia histórico-cultural. A antropologia inclui quatro paradigmas: o processo de hominização, o filosófico, o histórico e o cultural. Tais paradigmas correspondem a duas tendências contraditórias de desenvolvimento na globalização atual: uma é direcionada à uniformização, enquanto a outra se volta aos limites desse desenvolvimento e acentua as condições de diversidade cultural. Há uma dupla historicidade e culturalidade na antropologia que surge da historicidade e culturalidade das diferentes perspectivas de pesquisadores antropológicos e do caráter históricocultural dos conteúdos e dos temas de pesquisa. A relação entre pesquisa de uma única disciplina, interdisciplinar e transdisciplinar é uma questão fundamental na antropologia. Enquanto há muitas abordagens possíveis, a interdisciplinaridade e a transdisciplinaridade, como formas de organização, são particularmente adequadas para a pesquisa no campo da antropologia.
O uso do celular por estudantes na escola: motivos e desdobramentos
Authors: Nagumo Estevon , Teles Lucio
Published: January 2023

A sociedade contemporânea vivencia a era da conexão, mobilidade e ubiquidade na comunicação humana, desencadeando novas formas de interação e colaboração em redes e ambientes on-line . Neste contexto, há uma disseminação crescente e acelerada do uso de aparelhos móveis, e inevitavelmente esse uso começa a ocorrer com mais frequência na escola. O objetivo desta pesquisa foi compreender os motivos e desdobramentos do uso dos aparelhos celulares pelos estudantes na escola. A metodologia utilizada foi a Teoria Fundamentada (Glaser; Strauss, 1999) e os dados foram obtidos por meio de interações no Twitter, questionário e entrevistas on-line com estudantes que estivessem acessando a internet na escola por meio de um aparelho móvel. Com base nos dados coletados, foram elaboradas quatro categorias explanatórias do uso do celular na escola por estudantes: regras, uso didático, motivação e consequências. A partir da análise dos dados, nota-se que, em geral, as escolas tendem a proibir o uso, contudo, os estudantes costumam transgredir, utilizando seus celulares em virtude do tempo livre na escola ou do tédio nas aulas. Além disso, relata-se o uso com a finalidade de acesso às redes sociais, de distração e de pesquisa de conteúdo relacionado às disciplinas. Neste cenário, indica-se que a escola compreenda as questões sociais e culturais relativas à cibercultura dos jovens e perceba o fenômeno como uma oportunidade de aproximação e aprendizagem mútua.
Narrativas autobiográficas de surdos ou de pessoas com deficiência visual: análise de identidades e de representações
Authors: Müller Janete , Mianes Felipe
Published: January 2023

Articulado aos estudos culturais em educação, objetiva analisar os processos identitários e as representações de sujeitos surdos ou com deficiência visual, problematizando relatos escolares em narrativas autobiográficas. Assim, investigam-se oito obras que circulam no mercado editorial, percorrendo diferentes espaços e tempos, de modo a conferir um panorama sobre as experiências de in/exclusão de “sujeitos considerados diferentes” nas escolas comuns, sobretudo no ensino fundamental. No diálogo com teorizações sobre narrativas de si, identidades e representações, a análise do material empírico possibilita observar a dificuldade em acessar e garantir uma educação inclusiva a sujeitos surdos ou com deficiência visual. Narrando e resistindo a representações pejorativas, esses sujeitos tensionam processos de normalização, autoafirmam suas posições identitárias em grupos minoritários e reivindicam o direito à diferença. Uma inclusão não excludente permite a acolhida ao diferente e a “sensação de inclusão”, potencializando suas possibilidades de aprendizagem.
Contribuições ao debate sobre gestão democrática da educação: foco em legislações municipais sul-rio-grandenses
Authors: Esquinsani Rosimar
Published: January 2023

Intenta contribuir ao debate sobre gestão democrática do ensino público mediante o mapeamento de legislações municipais sobre o tema, focalizando o provimento do cargo de gestor escolar e tendo como lócus de pesquisa as redes municipais dos 12 municípios mais populosos do Rio Grande do Sul. No mapeamento e exame dessas legislações municipais, a pesquisa contribui para o debate em duas vertentes: a) necessidade contextual e premente da existência de legislações que regulamentem a questão da gestão democrática pois, b) no silêncio da lei, há um possível emparelhamento desse conceito ao mecanismo/ação da eleição de diretores/gestores. Adotando metodologia analítico-reconstrutiva, a investigação baseia-se em análise documental e no estabelecimento de categorias-chave que auxiliam na problematização dos achados da pesquisa. Conclui que o avanço democrático conquistado pelos municípios foco da análise ratifica a necessária regulamentação da gestão democrática, a fim de evitar que um dos mecanismos ou ações desta – a eleição de diretores – represente a integralidade do conceito.
Rodas de pesquisa e formação em educação especial: as trajetórias de estudantes com deficiência
Authors: Haas Clarissa , Pantaleão Edson , Orlando Rosimeire , Baptista Claudio
Published: January 2023

Objetiva discutir as trajetórias dos estudantes com deficiência por meio da produção acadêmica da educação especial e da documentação oral proveniente de uma ação de investigação e formação a qual envolve três grupos de pesquisa, de três universidades federais brasileiras distintas, que investigam essa área. A abordagem do estudo é de natureza qualitativa, sendo que as análises foram organizadas em três eixos temáticos tratados como dimensões emergentes de reflexão para a análise da política de educação especial na atualidade: 1) trajetória escolar do sujeito com deficiência e a relação com o espaço institucional; 2) sujeitos que desafiam a inclusão escolar – estudantes com deficiência mental/intelectual e jovens e adultos com deficiência; 3) trajetórias de interpretação da política de educação especial nos cotidianos. O estudo identifica como desafio central da política da educação especial na perspectiva da educação inclusiva a promoção da inclusão escolar como uma ação de autogestão dos cotidianos que requer o planejamento e o investimento persistente ao longo do tempo, favorecendo a construção das trajetórias escolares dos estudantes com deficiência e conciliando a necessidade de propor uma configuração coletiva capaz de acolher o aluno em sua individualidade e integralidade, independentemente de sua faixa etária ou tipologia de deficiência.
Educação ambiental crítica para a conservação da biodiversidade da fauna silvestre: uma ação participativa junto ao Projeto Flor da Idade, Flor da Cidade (Itirapina-São Paulo)
Authors: Da Silva Nathália , Ruffino Paulo Henrique
Published: January 2023

Diante das diversas ameaças que vêm comprometendo a biodiversidade, são de suma importância ações de educação ambiental (EA) que sejam voltadas para a conservação. Nesse contexto, a presente pesquisa foi desenvolvida no Projeto Flor da Idade, Flor da Cidade (PFIFC), cujo funcionamento se dá na Estação Experimental Itirapina, interior do estado de São Paulo. A pesquisa baseia-se numa perspectiva de EA crítica e tem como objetivo identificar as concepções dos jovens do projeto socioambiental em relação à conservação da fauna silvestre, de maneira a promover ações ambientais proativas de conservação a partir de práticas educativas e do desenvolvimento de material educativo pelos próprios  participantes. Todos os 29 jovens do projeto tinham entre 13 e 17 anos e, de 2014 a 2015, participaram dos 14 encontros, nos quais diferentes temas foram abordados por meio de apresentações interativas, materiais didáticos dinâmicos, visita à exposição “Bicho: quem te viu, quem te vê” e saídas de campo nas áreas protegidas. Assim, de acordo com a metodologia qualitativa, realizou-se o levantamento das concepções desses jovens sobre o tema mediante um questionário e, considerando a análise dos dados, concluiu-se que a maioria dos jovens compreendeu os conceitos acerca dos temas e mostrou uma maior preocupação com a conservação da fauna, apresentando uma mudança de atitude por meio de produção e divulgação de materiais relativos à preservação da biodiversidade local.
Consequences of an Analysis Using Biblical Analogies for Automated Vehicle Control Design
Authors: NÉMETH Balázs
Published: January 2023

The paper proposes an analysis of learning-based approaches for automated vehicle control systems from an ethical viewpoint. An analysis using analogies between selected biblical texts and operation concepts of learning-based approaches is per-formed. Thus, analogies for supervised, unsupervised, and reinforcement learning-based approaches are created. Through the analogies, the root of the automatic control design problems, i.e. forming objective functions, on a theological level is explored. The analysis leads to three consequences, which are related to the difficulty of forming control objective, the difficulty of considering human objectives in control, and the necessity of viewing systems in all their complexity. The paper proposes the application of the consequences in an illustrative route selection vehicle control example. A multi-layer control concept involving the consequences of the analysis is proposed, with which some ethical challenges of the selected control problem can be handled.
Karacs Teréz pedagógiája. Vallástanítás a miskolci Felsőbb Leánynevelő Intézet-ben
Authors: BÁTORINÉ MISÁK Marianna
Published: January 2023

Pedagogy of Teréz Karacs. Teréz Karacs was one of the remarkable pioneers of her age in national female edu-cation, with a unique working ability, steadiness, and power. The Trans-Tisza Re-formed Diocese, specifically the congregation of Miskolc, can also be very thankful to her. The pedagogy of Karacs was not just up to date but beyond her age. She opened the doors of her finishing school under such harsh circumstances and in an age in which others closed their institutions. Inviting the magistracy of the congre-gation, she received many promises for the unperturbed functioning of her school; however, the lack of finances meant a permanent struggle in the maintenance of the girls’ school. She also gave in her notice many times because of the unrealized prom-ises. Teréz Karacs trained hundreds of girls in her consistent, thorough, and practi-cal pedagogic method and prepared them for life. She did all her work with such a conviction that her efforts are not purposeless, serving and advancing her country, nation, and church. The upper finishing school of Miskolc put a great effort in the education of re-ligion, which principally meant the shaping of a virtuous life, the inner piety in the century of rationalism and liberalism. Besides various subjects, religious education and nurture played an important part in the education of the girls in her institute. These tendencies also bore the marks of everyday life of the ecclesiastic life of the country. In spite of the fact that religious education appeared from the first lesson of the beginners, she did not mention it in her work Some Words on the Education of Girls. Negligence or slight of religious education would not even befit the careful work of Teréz Karacs, who meant to educate trustful and cultured women.
A „Lélek által való nemesedés” szolgálata. Református kollégiumok küldetése a tehetségek támogatásában
Authors: FEHÉR Ágota
Published: January 2023

Service of “Nobility through the Spirit”. The Mission of Reformed Colleges to Support Talent. In the community of Reformed institutions, children’s growth is accompanied by educators whose mission is a call from God, in the spirit of which they seek to convey the word of the Bible to children. The main message of nurturing talent is to help all students become aware of the abilities they have received from God personally. Reformed colleges play a special role in this and build on significant historical traditions, and see nurturing talent as a process of complex personal development. The aim of the present study is to examine the mission of Reformed colleges in relation to talent development by highlighting two examples: the role of the Reformed College in Sárospatak and of that in Pécs in supporting talent. The sources used were school bulletins and yearbooks.
Dealing with Guilt in Pastoral Care
Authors: KISS Jenő
Published: January 2023

This study starts from the current experiential reality of the family, described by sociologist Peter V. Zima as follows: The family, as a victim of society as an alienating structure, becomes itself an alienating structure, which makes it impossible to establish intimate and supportive relationships between family members and the future of the family.
The family therefore fails to fulfil its original role of being a place of embeddedness and a resource for society. It is also hampered by transgressions while hindering the search for fairness towards each other. Pastoral care can help families to recognize the essence of guilt and then seek effective resources of help. The paper, therefore, highlights the fundamental relational nature of human existence and the existential nature of guilt through philosophical, theological, and biblical anthropology (1). It then highlights the importance of the notion of existential guilt in contextual perspectives, therapy, and pastoral care (2). Finally, following a theological interpretation of the concept of guilt, it identifies in four points the areas in which the use of the concept of existential guilt in pastoral care is helpful (3).
Spiritualitás a vallásfenomenológia és pasztorálpszichológia horizontján/ 2
Authors: KOVÁCS Szabolcs
Published: January 2023

Spirituality at the Horizon of Religious Phenomenology and Pastoral Psychology/ 2. We are living in a designer world, where not only the circumstances but our gods will be created consciously. We hunger for a god. Choosing an inadequate god, a god too small to transcend our limitations and who, therefore, can neither save nor transform us drives us to keep hunting. This study outlines the phenomenology of Christian spirituality, religious practice and highlights their working field. We find correlation between spirituality and spiritual well-being and happiness, factors that contribute to a positive personal development. We are condemned to meaning. There is a universal impulse to endow our joys and sorrows with meaning. Christian spirituality is a condition for us to reframe and understand our life perspectives and reach the “Courage to Be” (Tillich).
Analysis Of Student's Learning Activity And Creative Thinking In Face-To-Face Learning Limited In The Transition Period
Authors: Mahmudah  , Ghina Amaliatul Khasanah  , Makherus Sholeh
Published: January 2023

The purpose of this research is to determine the activeness of students' learning and creative thinking of students while face-to-face learning is limited to the transition period in thematic subjects of grade VI elementary school. The form of research used is qualitative. The subjects in this study were homeroom teachers and students of class VI Darul Hijrah, Kelumpang Hilir District, Kotabaru Regency, totaling 20 students, for the 2021/2022 school year. The respondents that the researchers succeeded in getting were as many as 20 populations. Data collection techniques used are question and answer and direct observation. The results of the study stated that 75% of student learning activities were in the good category, namely students were able to achieve the parameters of student learning activity. Meanwhile, students' creative thinking skills at the time of face-to-face learning were limited to 68% in the good category, and were able to achieve the parameters of creative thinking abilities

 

ABSTRAK:
Structures of the covariance matrix: An overview
Authors: Janiszewska Malwina
Published: January 2023

In this paper, some multivariate and double multivariate modelling approaches are presented. Moreover, this article provides an overview of the modelling of the structure of the covariance matrix. Furthermore, some methods of covariance structure identification are given.
The Use of Cybernetic Systems Based on Artificial Intelligence as Support for the Decision-Making Process in the Military Field
Authors: Popa Eugen Valeriu
Published: January 2023

In the future, at the strategic, operational, and tactical levels of warfare, replacing human will and human decision with autonomous Artificial Intelligence (AI) weapon systems becomes every day a high possible scenario. These systems are already in use and have the ability to successfully deal with threats faster than humans. Countering AI weapon systems will represent a great challenge in a future war. Both military and commercial robots will in the future incorporate “artificial intelligence” (AI) that could make them capable of performing tasks and missions on their own. In the military context, this gives rise to a debate as to whether such robots should be allowed to carry out missions, especially if there is a possibility that any human life may be in the line of fire. Thus, it can be stated that unconventional knowledge will be required for successfully defeat of such a weapon system.
Inhibitory test of turmeric leaves extract (Curcuma Longa. L) against the growth of Streptococcus mutans bacterial growth in vitro
Authors: DOHUDE Gostry Aldica , RUSDY Hendry , HANAFIAH Olivia Avriyanti , JOHAL Preetypal Kaur
Published: January 2023

Streptococcus mutans is a bacterium that plays an essential role in forming dental caries. Odontogenic infection is an oral cavity infection that can develop from dental caries if not appropriately treated. Caries treatment can be done with the use of antimicrobial agents. The increasing resistance to antimicrobial drugs has made herbal medicines the choice because they are more effective and less harmful. The community uses turmeric leaves as a cooking spice and treatment for stomach aches in children. Turmeric leaf extract contains flavonoids, tannin, and phenolic antimicrobial active compounds. This research aims to find out if turmeric leaf extract inhibits the growth of the Streptococcus mutans. This study uses a post-test-only control condition approach in a laboratory setting. The concentration of turmeric leaf extract tested was 10%, 15%, and 20% with the positive control (Chlorhexidine 0,2% mouthwash) and negative control (DMSO) with five repetitions. Antibacterial effectiveness test using Kirby-Bauer disc diffusion method. The data analysis using ANOVA showed a p-value of 0.00 on inhibition, which indicates that turmeric leaf extract can suppress the development of Streptococcus mutans. The average inhibition zone obtained was 8.7 mm at a concentration of 10%, at a concentration of 15% at 9.5 mm, and at a concentration of 20% at 8.54 mm. This research concludes that turmeric leaf extract can inhibit the proliferation of Streptococcus mutans bacteria KEYWORDS: Turmeric Leaf, Streptococcus mutans, Antibacterial