bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of the electrophysiological mechanisms of anticonvulsant action of the original levetiracetam analog the compound GIZH-290
Authors: Voronina T. A. , Litvinova S. A. , Gladysheva N. A. , Yakovleva А. A.
Published: September 2021

The study used the method of cobalt epilepsy, which allows rats with long-term implanted electrodes in the cortical and subcortical structures of the brain to monitor the dynamics of the formation and migration of Epi-foci for a long time. It was found that in the control at the 1st stage of development of the Epi system, Epi activity is most pronounced in the electrocorticograms of the ipsilateral cortex, and at the 2nd, stable stage of development of the Epi system – in the contralateral cortex and subcortical structures. The compound GIZH-290 (the original structural analogue of levetiracetam) reduces the number of Epi discharges and their duration at the 2nd, stable stage of the development of the Epi system. The target structure of the GIZH – 290 compound was the hippocampus. The compound GIZH -290 selectively statistically significantly reduces both the number and duration of Epi – discharges only in the hippocampus and does not affect the foci of epileptic activity in the ipsi-and contralateral cortex and hypothalamus.
Axiological Aspects of Anthropological and Social Sources of Law Formation
Authors: ZHURAVSKA Olena
Published: September 2021

The article analyses some axiological aspects of anthropological and social sources of law formation through the analysis of the system, which includes social (legal) values and principles of law. It is emphasized that such division and delimitation are quite conditional, since principles provide for the requirement of guidance by values. Significant social idea that has become a legal value is reflected in the principle of law, and is governed by law. It has been proved that the legitimacy of positive law in a modern state-organized society, which is characterized by such phenomena as the rule of law and civil society, is directly related to the extent to which it reflects social values. The source of law becomes in demand if the proposed model of behaviour provides protection, provision, reproduction of socially recognized value that is important to society. The public significance of the behaviour model receives legal support, public perception and reproduction in the course of social practice. Over time, the most important legal values are transformed into the principles of law and are concretized in legal norms. Among the most expressive legal values that are clearly reflected in international and national law there is human dignity, freedom, justice and equality. Human dignity is the basic idea of humanism, which proclaims the protection of a person, his/her rights and freedoms; the satisfaction of his/her interests and needs. In the national legal system, this value is reflected in the Constitution, which recognizes a person, his/her life and health, honour and dignity as the highest social value. The Constitutional Court of Ukraine recognizes human dignity as a system-forming value and a source of human rights. Freedom includes the issue of potential and real ability of a person to be a subject of law, reflected in the form of such principles of law as general permission and special permission. Justice as a legal value is a special mechanism for maintaining the balance of legal values, a means of justifying and recognizing legal restrictions, a criterion for assessing legal phenomena and institutions. Equality in law is understood today as equality of opportunities and is reflected in the form of the following interrelated aspects: equality before the law; equality before the court; equality of rights, freedoms and responsibilities of a person and citizen.
Digitalization of Provision of Administrative Services in the Field of Construction
Authors: TUROVETS Yurii
Published: September 2021

In the article the author explores the main problems of digitalization of administrative services in the field of construction. It is indicated on the validity of the grounds for digitalization of administrative services. The author determines that administrative services in the field of construction are accompanied by a significant share of corruption risks. In the article, the author substantiates that the digitalization of administrative services in Ukraine, including in the field of construction, is an ongoing process that is undergoing significant changes. It is emphasized that during 2020 the national legislation underwent significant changes in the study area, but they did not bring the expected result due to several factors, including political. The author argues that the initiated changes in the functioning of the electronic system in construction will contribute to the legislative definition of the concept of a single state electronic system in construction, ensuring accessibility, convenience, transparency of administrative services in construction, openness, accessibility, reliability, relevance, completeness and security, information (data) of the electronic system, etc. The author argues that declaring equal status and legal force of information and documents will have real results only if such recognition is fully operational for all types of documents at the level of all types of administrative services, especially those with a relevant list of documents in the field of construction. The main factors hindering the development of digitalization of administrative services in the field of construction are substantiated (lack of political will in the issue of radical reform of the system of bodies in construction and urban planning; inertia of the system of administrative services in digitalization, etc.). The author argues that the advantages of using modern information technology in the provision of services in the field of construction are maximum transparency and reduction of corruption risks in construction. However, to implement the project of digitalization of the provision and receipt of administrative services, it is necessary to work more deeply on the regulatory framework in this direction and minimize the impact on human decision-making on the provision of administrative services.
STRUCTURAL ELEMENTS OF THE INTELLECTUAL INFRASTRUCTURE POTENTIAL TECHNOLOGICAL DEVELOPMENT
Authors: Миллер Александр Емельянович
Published: September 2021

В статье исследуются теоретические аспекты потенциала интеллектуальной инфраструктуры технологического развития промышленных предприятий. Раскрыты специфические признаки и обоснованы элементы потенциала интеллектуальной инфраструктуры технологического развития. Предложен универсальный метод оценивания потенциала интеллектуальной инфраструктуры технологического развития.

The article explores theoretical aspects of the potential of the intellectual infrastructure of technological development of industrial enterprises. Specific features are disclosed and elements of potential of intellectual infrastructure of technological development are justified. Universal method of assessment of potential of intellectual infrastructure of technological development is proposed.
THE PROBLEM OF REDUCING THE PAYMENT FOR THE SERVICES OF A REPRESENTATIVE
Authors: Ряполов Никита Александрович , Рубцова Наталья Васильевна
Published: September 2021

В статье освещена проблема оплаты услуг представителя. Рассмотрена позиция Верховного суда РФ, а также мнение адвокатского сообщества. Представлены точки зрения действующих адвокатов и иных авторов, изучающих данную проблематику. По их мнению, сложившуюся ситуацию не стоит замалчивать, а продолжить активно обсуждать.

The article highlights the problem of paying for the services of a representative. The article considers the position of the Supreme Court of the Russian Federation, as well as the opinion of the legal community. The points of view of current lawyers and other authors studying this problem are presented. In their opinion, the current situation should not be hushed up, but continue to be actively discussed.
BUILDING AN INNOVATIVE OPEN EDUCATION ECOSYSTEM OF A MODERN UNIVERSITY
Authors: Хмелева Галина Анатольевна
Published: September 2021

В статье обоснована необходимость формирования открытой инновационной образовательной экосистемы как парадигмы современного конкурентного университета. Ключевое значение для такой системы имеют гибкие образовательные стандарты, сокращение количества проверок вузов, проверяемых показателей, технологическое оснащение, цифровые компетенции преподавателей.

The article substantiates the need for the formation of an open innovative educational ecosystem as a paradigm of a modern competitive university. Of key importance for such a system are flexible educational standards, a reduction in the number of inspections of universities, verifiable indicators, technological equipment, and digital competencies of teachers.
Glacial erratics on the Arctic Ocean margin of North Greenland: implications for an extensive ice-shelf
Authors: Dawes P. R.
Published: September 2021

Glacial erratics of high-grade metamorphic and plutonic rocks occur on the northern coast of Peary Land on the edge of the Arctic Ocean. Crystalline terrain is not exposed in Peary Land; sample sites are 250 km distant from the present-day Inland Ice which covers the nearest potential source - the Greenland shield. The dominant till clasts are locally derived from a northern ice-cap that coalesced during the late Wiscon- sinian glacial maximum with the Inland Ice at about 82°30'N.
Recent Quaternary mapping by the Geological Survey of Greenland failed to locate crystalline erratics in northernmost Peary Land; consequently prominence is given to early observations. The present paper describes a collection of erratics made in 1969. Conveyance mechanisms, viz. ice-cap regime (glacier or ice-shelf) contra drifting ice (icebergs or sea ice) are discussed and possible transportation paths are sum­marised.
Based on rock type and mineralogy, the Greenland shield is the most likely source of the erratics and derivation from an expansion of the Inland Ice around eastern Peary Land the most logical glacial model. However, such a provenance contravenes with the presently available on-shore data which indicate an eastwards Weichselian ice flow along the coast. Instead of invoking a rather complicated glacial history for Peary Land, involving different land ice regimes, an alternative glacial model based on an extensive Greenland - Ellesmere Island ice-shelf is outlined.
Effect of induced ripples on the electronic properties of graphene monolayer: Simulation study
Authors: Ahmad Mohammad S , Talla Jamal A
Published: September 2021

The effect of tensile stress on the electronic properties of pristine graphene mono-sheet was investigated. We applied different stress factors in order to investigate the mechanical and electronic properties of graphene monolayer. As a consequence of the applied tensile stress, different patterns of ripples were created. Whereas, different rippling levels were significantly tuned the electronic properties of the graphene monolayer. For instance, the band gap of graphene monolayer dramatically increased with increasing the tensile stress factor. Moreover, the combined effect of applying tensile stress as well as bending the sheet significantly modified the band gap. However, applying more tensile stress induced a reverse behavior. We highly believe that, controlling local curvatures of graphene monolayer opens up opportunities for strain assisted tuning of local electronic structure such as band gap engineered devices.
Adapting Pedagogy to Cultural Context
Authors: Jukes Matthew C. H. , Sitabkhan Yasmin , Tibenda Jovina J.
Published: September 2021

This paper argues that many pedagogical reform efforts falter because they fail to consider the cultural context of teacher and student behavior. Little guidance exists on how to adapt teaching practices to be compatible with culturally influenced behaviors and beliefs. We present evidence from three studies conducted as part of a large basic education program in Tanzania showing that some teaching activities are less effective or not well implemented because of culturally influenced behaviors in the classroom, namely children’s lack of confidence to speak up in class; a commitment to togetherness, fairness, and cooperation; avoidance of embarrassment; and age-graded authority. We propose ways teaching activities can be adapted to take these behaviors into account while still adhering to fundamental principles of effective learning, including student participation in their own learning, teaching at the right level, and monitoring students as a basis for adjusting instruction. Such adaptations may be made most effective by engaging teachers in co-creation of teaching activities.
Sensory Attributes of Jackfruit beyond Meat Sandwich Filling
Authors: Uruakpa Florence Ojiugo , Nanayakkara Ruchithri , Pavel Lauren , Robinett Tessa
Published: September 2021

Jackfruit is used as a meat substitute by some consumers but reports on its use are scanty. Jackfruit is becoming popular among meat lovers who want non-soy-based meat alternative. Thus, this study aims to 1) discover a healthy and affordable option to meat and 2) assess if consumers candifferentiate between pulled pork and jackfruit in a sandwich. Three types of sandwiches were prepared (i.e., jackfruit-in-water; pork tenderloin; jackfruit-inbrine). Sensory analysis using 300 untrained panelists was conducted to examine selected quality attributes (flavor, texture, aroma) and identify the meat-based sample. Panelists scored the sandwiches on a scale of 1-3 with 1 being most favored. The mean scores were calculated as follows: pork = 1.54), jackfruit in brine = 2.16), and Jackfruit in water = 2.18. Statistical analysis (2 tailed T-test) found a significant difference (p = 0.003) in flavor between thepork sandwich (score = 1.6) and those of jackfruit in brine (score = 2.17) and water (score = 2.17). There was a significant difference (p = 0.05) in the texture of pork sandwich (score = 1.6) and jackfruit sandwich in brine (score = 2.0) and water (score = 2.3). Most tasters thought the jackfruit was a meat product although the meat product was ultimately favored. Participants did not know that the sandwiches had a meat substitute. Jackfruit could be a desirable meat substitute for consumers who are looking for low-fat meat alternative rich in antioxidants to add to meals.
IoT Based Image Processing Filters
Authors: Abbas Noor , Shujaa Mohamed Ibrahim , Zghair Entithaar Mhwes
Published: September 2021

Internet of things (IoT) becomes the backbone of the advanced countries and it has a real contribute to exchange the traditional style or way of practical life, even personal life into smart style, with (IoT) technology the life become more and more easy and professional. internet of things achieves various applications coordinate with sensors and standard protocols to apply what is called machine -to- machine connection (M2M), in this paper we will talk more about the concept of (M2M), the main component of internet of things and finally the common protocols that is used in network, in addition to that this work present an IOT operation with processing system using camera for capturing image and Xilinx system generator(XSG)models for designing  image processing algorithms and the result of  the processing is an image with black and white for edge detection and Thresholding models  and gray color image for gray enhancement model.
Survey on CNN based super resolution methods
Authors: Kazem Rafaa Amen , Suad Jamila H. , Abdulbaqi Huda Abdulaali
Published: September 2021

Super Resolution is a field of image analysis that focuses on boosting the resolution of photographs and movies without compromising detail or visual appeal, instead enhancing both. Multiple (many input images and one output image) or single (one input and one output) stages are used to convert low-resolution photos to high-resolution photos. The study examines super-resolution methods based on a convolutional neural network (CNN) for super-resolution mapping at the sub-pixel level, as well as its primary characteristics and limitations for noisy or medical images.
CEVİZ (Junglas regia L.) YETİŞTİRİCİLİĞİNDE CBS TEKNİKLERİ KULLANILARAK MEKÂNSAL KARAR DESTEK SİSTEMİ (MKDS) GELİŞTİRİLMESİNDE ÇATAK-VAN (TÜRKİYE) ÖRNEĞİ
Authors: KANDİLLİ Mehmet , KAZANKAYA Ahmet , DOĞAN Adnan
Published: September 2021

This study was carried out to determine the areas where walnut (Junglas regia L.), which is grown in different ecological conditions of the world and Anatolia and provides significant added value to the economy of the region and the country, can be grown within the borders of Çatak (Van) district by using GIS. Within the scope of the study, certain data sets were created by taking into account the factors affecting the cultivation of walnuts, previous studies and expert opinions in determining the optimum areas where walnuts can grow in Çatak district. These data sets were combined with the necessary elements in the raster thematic maps and climatic vector maps (E00 maps with the e-high curve) and then they transferred into the database. All the obtained data were compared with each other by using GIS software and the areas where walnut could grow were determined. Due to the topographic structure of Çatak district, it has been concluded that walnut can be grown in valleys, slopes and floors where the altitude and slope are relatively low, but it will not be suitable for cultivation in mountainous areas. Thanks to this study, it will be used both in revealing the agricultural potential of different areas where walnut orchards can be established in Çatak (Van-Turkey) district and it will be also used in managing information based on locations.
Staphylococcus epidermidis biofilms: Functional molecules; relation to virulence and the host immune response
Authors: Abdul Fatima , Raheem Ihsan , Abdulrazaq Raghad , T. Subhi Hanan
Published: September 2021

Staphylococcus epidermidis is the most significant nosocomial pathogen related to people with vulnerable frameworks such as malignant growth patients, neonates, and foreign body embedded materials such as heart valves. A few virulence factors in S. epidermidis can cause host damage in comparison to Staphylococcus aureus. In spite of that, the key roles of S. epidermidis virulency rely on biofilm formation, bacterial biofilm is essential for the pathogenesis by encouraging microorganisms to consist shape networks of assurance rather than free planktonic cells, hence resistance to antibacterial agents, and medically uninsured problems by colonizing medical indwelling, making the disease long span, and difficult to treat. The National Institute of Health (NIH) reported 65-80% of bacterial illnesses are biofilm formed, thus making numerous passing wellbeing additional costs. Therefore, the biofilms establishing on the susceptible hosts' tissues demonstrate; preventing antibiotics efficient treatment, protecting against host defense mechanisms, and announce the bacteria virulence determinants manifesting.
Evaluation of Health and Environmental Safety in Food and Water Production Factories in Duhok Governorate
Authors: Abdulrahman Masood , Bebo Kherailah
Published: September 2021

Lack of adequate occupational safety and health strategies is a reason that workplace accidents in food and water production industries remain high, making this sector one of the riskiest operations worldwide. The research was carried out to examine the degree of implementing the health, occupational and environmental safety measures in the selected factories to assess health and safety level and to measurement the noise levels in these industries. A cross-sectional survey was conducted by utilizing structured pre-tested questionnaire and noise level measured at four places: selling, administrative, machine and passage industry places. The study revealed the absence of health and safety policy, and the absence of safety and training departments. The suitable measures in place to combat harmful dust generated by motor traffic were present in 23.3%, and the system with deal with the spillage was current in 43.3% of factories. Wastes segregation was found in 3.3%. Exhaust dilution ventilation system was seen in 83.3% of these factories. Personal protection equipment was not provided to all workers exposed to dust, fumes, or gases. Only 3.3% of factory staffs were aware of fire prevention and safety measures. The sound level at the machine place was above average (above 85 decibels) in all factories.
Miteigentum an Grundstücken und einfache Gesellschaft
Authors: Roth Nicole
Published: September 2021

Although there is agreement that a pro rata entitlement is permissible in the simple partnership, the necessary interaction of Art. 646 ff. ZGB on co-ownership law and Art. 530 ff. OR on the law of the simple partnership is dealt with only rudimentarily. This is the point at which the work picks up, in that the two institutes of co-ownership and simple partnership are examined individually as well as in relation to their coordination possibilities in the case of real estate. The fundamental discussion of the legal institutions of co-ownership and simple partnership yields further insights of practical relevance. Thus, the delimitation difficulties between co-ownership and joint ownership as a result of simple partnership are also presented, general indications for the structuring of an agreed co-ownership arrangement are provided, and the concerns raised in the doctrine regarding pro rata entitlement in simple partnership are discussed.
Weather dependence of medical rehabilitation efficiency in patients with ischemic heart disease on the resort of the South Coast of Crimea
Authors: Ivaschenko A. S. , Ezhov V. V. , Yezhova L. V. , Yanovskiy T. S. , Mizin V. I. , Yarosh A. M. , Grigoriev P. E. , Pyankov A. F.
Published: September 2021

The aim of this work is to assess the influence of the climatic and weather characteristics of the South Coast of Crimea (SCC) on the effectiveness of health resort medical rehabilitation (MR) of patients with ischemic heart disease (IHD).

Materials and methods. A study was carried out in a group of 276 patients with IHD. The influence of climatic and weather characteristics of the SCC were assessed using the methods developed by the «ARI n.a. I.M. Sechenov» - modified clinical index on weather pathogenicity (CIPP-M) and MR assessment according to the criteria of the» International classification of functioning, disabilities and health» (ICF).

Results. Regression equations for the dynamics of the ICF b2401, b280, b4301 and b440 domains on the values of air temperature (AT-M), atmospheric pressure variability (APV), air temperature variability (ATV-M) wind speed (WS-M) and total CIPP-M have been developed, which allow to reliably form a rehabilitation prognosis for patients with IHD for all terms of health resort treatment in the SCC.

Conclusions. The use of modernized clinical indices of weather pathogenicity allows one to adequately assess and predict the effect of weather dynamics and form a rehabilitation prognosis for patients with IHD.
ADVANCE research 20 years later
Authors: Kobalava Zh. D. , Kolesnik E. L.
Published: September 2021

Observational and interventional studies have shown that intensive blood pressure control may benefit in patients with diabetes. The Action in Diabetes and Vascular Disease: Preterax and Diarnicron MR Controlled Evaluation (ADVANCE) international randomized, controlled, clinical trial was launched in 2001. According to the results of the study, the risk of major micro- and macrovascular events (primary endpoint) significantly decreased by 9%, while the risks of cardiovascular death and death from any cause decreased by 18% and 14%, respectively. There was a decrease in the risks of microvascular complications – any renal event, the appearance or worsening of nephropathy and the appearance of microalbuminuria by 21%, 18% and 21%, respectively. The results of the antihypertensive part of the ADVANCE study supplemented the expanding evidence base and served as the basis for changing clinical guidelines for the management of patients with hypertension and diabetes. According to the updated joint guidelines of the European Society of 

Cardiology / European Association for the Study of Diabetes (ESC/EASD), the target systolic / diastolic blood pressure levels should be 130/80 mmHg, with some exceptions, and the fixed combination of the RAAS blocker with a diuretic or calcium antagonist is suggested as first-line therapy.

The observational ADVANCE-ON study, which enrolled 8494 patients out of 11 140 patients randomized to the ADVANCE study, found a memory effect, or ‘inheritance’, in which intensive blood pressure control during the study had a beneficial effect on various outcomes after its termination. These findings highlight the importance of achieving and maintaining optimal blood pressure control to reduce the risk of micro- and macrovascular complications.
The influence of geomagnetic and seismic parameters on mortality from cardiovascular pathologies in the Shamakhi Region of the Republic of Azerbaijan
Authors: Afandieva L. G.
Published: September 2021

Aim. Study of the dependence of mortality from CVD on helio-seismic indicators in the Shamakhi region of the Republic of Azerbaijan.

Materials and methods. 352 case histories of patients who died in 2013 from various diseases were reviewed. The relationship was established between the number of deaths, their causes, distribution by sex and age with the magnitude of earthquakes, the depth of the epicenter and seismological activity by months. The data obtained were statistically processed using the Statistica 12.0 for Windows software package (Statsoft Inc., USA). To establish correlations, Pearson Chi-Square Tests was calculated, the results were considered reliable at p <0.05.

Results. Statistically significant (p <0.001) more deaths were observed at the age of 80-89 years in men, and at the age of 70-79 years in women. Also, the relationship between mortality and the depth of the seismic process and the magnitude of the earthquake was established, in particular, the greatest number of deaths was observed at a depth of the seismic process <10 km and with a magnitude of 1.1-2.0 ml. In all months, the number of deaths was higher with a magnitude of 1.1-2.0 Ml. Statistically significant (p <0.005) was the fact that the nosology of the studied diseases was dependent on the age of the patients. Thus, a greater number of deaths in all age groups accounted for heart failure. A statistically significant (p <0.005) dependence of the depth of the seismic process on the month of death of patients was established, in particular, for all months, deaths coincided with the depth of the process less than 10 km. At the age of 40-70 years, a significantly greater number of deaths were from heart failure in men, and from 70 years and above in women.

Conclusion. Thus, there is a close correlation between geomagnetic changes and mortality from CVD, which is realized in the form of an increase in the frequency of cases and deaths, and the number of these cases increases with the age of patients and changes in the magnitude and depth of the earthquake.
Jesus Shall Reign? An Examination of Christian Mission to the Akan Palace
Authors: Opuni-Frimpong Kwabena
Published: September 2021

The Gospel and African Culture interface has remained an ongoing dialogue due to the fact of inherent tensions. The genuineness of the conversion of the traditional leadership institution that welcomed the Western missionaries has remained in doubt in some missionary established churches. The conversion challenges of the traditional leaders have resulted from ancestors and ancestorial related functions that traditional leaders performed. The churches over the years created mission fields and chaplaincies with trained personnel and resources to address conversion challenges of specific and unique communities. While the creation of mission fields and appointments of chaplains have made significant responses to the conversion challenges of the people involved, the conversion challenges that traditional leaders have constantly requested for support from the churches have not been fully addressed. The study is an examination of the requests of some traditional leaders for Christian missions to be extended to the Palace and responses made so far by some of the missionary established churches. The study adopts a qualitative approach with an examination of relevant available materials and interviews. The study points to the fact that the conversion of the Palace and its functionaries must be considered as a major ministry and mission field of the church with trained ministers and resources for the specialized mission field. The study moreover calls for deeper research into matters of ancestors and ancestorial related rites that have remained as areas of tension between the church and the conversion of the Palace functionaries.

Keywords: Palace, Christian Mission, Traditional Leadership, Chaplaincy, Conversion
Integrated therapy as a tool to help fight asymptomatic COVID-19: A case report
Authors: Tiwari Subodh , Sharma Shruti , Verma Anita
Published: September 2021

COVID-19 is a rapidly changing and evolving situation and is extremely challenging to the humankind since it is highly infectious. Around 80% of the COVID-19 patients are asymptomatic but still need special care so that they don’t develop any further serious complications in due course of infection. The aim of present case study was to assess the effect of integrated therapy of yoga and Ayurveda on vital parameters of a COVID-19 positive asymptomatic patient. He was found to be COVID-19 positive with ORF CT value of 29.85. He remained asymptomatic throughout the course of disease. Vital parameters such as body temperature, oxygen saturation, and heart rate remained optimal throughout the course of infection. This was probably due to physical activity such as walking, yoga and Ayurvedic medications which helped in building of immunity. This further prevented progression of the disease to moderate/severe stage and there were no unanticipated events. The patient was rechecked after 8 days and was found to be COVID-19 negative. This implies that Yoga and Ayurveda treatment is effective in controlling symptoms of COVID-19 and prevention of disease progression.
Early toxicities of ultrahypofractionated stereotactic body radiotherapy for intermediate risk localized prostate cancer using cone-beam computed tomography and real-time three-dimensional transperineal ultrasound monitoring
Authors: Lee Eric Ka-Chai , Leung Ronnie Wing-Kin , Luk Hollis Siu-Leung , Wo Barry Bar-Wai
Published: September 2021

Purpose: Image-guided radiotherapy (IGRT) is central to the safe and effective delivery of ultrahypofractionated (UF) stereotactic body radiotherapy (SBRT) for localized prostate cancer. However, the optimal IGRT modality remains uncertain. We aim to study the safety of performing UF-SBRT using cone-beam computed tomography (CBCT) and real-time transperineal ultrasound (TPUS) monitoring. Materials and Methods: We retrospectively review the medical records of 26 patients who had received UF-SBRT for intermediate risk localized prostate cancer in our institution from October 2018 to December 2020. All patients were treated with SBRT without fiducial marker and received 35–40 Gy to the clinical target volume in 5 fractions over 2–5 weeks. CBCT was used to correct for interfraction displacement while intrafraction displacement of the prostate gland was monitored using Elekta Clarity Autoscan TPUS with 4 mm isotropic warning level. All patients also received neoadjuvant and concurrent androgen deprivation therapy for a total of 6 months. The primary endpoints were incidence of acute toxicities and patient reported urinary toxicities in terms of the International Prostate Symptom Score: before (IPSS1), at the completion of (IPSS2), and at 3–6 months (IPSS3) after SBRT. Results: All men were treated and followed up for at least 3 months after SBRT. Patients experienced transient worsening of their urinary symptoms at the end of SBRT but they usually recovered in 3–6 months afterwards. The median IPSS1, IPSS2, and IPSS3 were 12, 12.5, and 8, respectively. One patient developed grade 3 rectal bleeding which was related to underlying hemorrhoid. No other grade 3–4 acute toxicity was observed. Conclusion: It appears safe to deliver UF-SBRT without fiducial marker for prostate cancer patients using CBCT and non-invasive hybrid imaging modalities for positioning and tracking. Longer follow-up is necessary to monitor the treatment efficacy and long-term toxicities.
ecoTeka, Urban Forestry Data Management
Authors: Aloui Mathias , Duhamel Gaëtan , Frédout Manon , Rovellotti Olivier
Published: September 2021

It is now well known that a healthy urban ecosystem is a crucial element to healthier citizens (Astell-Burt and Feng 2019), better air (Ning et al. 2016) and water quality (Livesley et al. 2016), and overall, to a more resilient urban environment (Huff et al. 2020). With ecoTeka, an open-source platform for tree management, we leverage the power of OpenStreetMap (Mooney 2015), Mappilary, and open data to allow decision makers to improve their urban forestry practices. To have the most comprehensive data about the ecosystems, we plan use all available sources from satellite imagery to LIDAR (light detection and ranging) and compute them with the DeepForest (Weinstein et al. 2020) learning algorithm. We also teamed with the French government to build an open standard for tree data to improve the interoperability of the system. Finally, we calculate a Shannon-Wiener diversity index (used by ecologists to estimate species diversity by their relative abundance in a habitat) to inform the decision making of urban ecosystems.
Morphology and molecular study of three new Cordycipitoid fungi and its related species collected from Jilin Province, northeast China
Authors: Hu Jia-Jun , Zhao Gui-Ping , Tuo Yong-Lan , Dai Dan , Guo Di-Zhe , Rao Gu , Qi Zheng-Xiang , Zhang Zhen-Hao , Li Yu , Zhang Bo
Published: September 2021

Cordyceps species are notable medicinal fungi in China, which are pathogenic on insects and exhibit high biodiversity in tropical and subtropical regions. Recently, three new Cordyceps species, Cordyceps changchunensis and Cordyceps jingyuetanensis growing on pupae of Lepidoptera and Cordyceps changbaiensis growing on larvae of Lepidoptera, were found in Jilin Province, China and are described, based on morphological and ecological characteristics. These three new species are similar to the Cordyceps militaris group, but are distinctly distinguishable from the known species. Cordyceps changchunensis, characterised by its small and light yellow to orange stromata which is occasionally forked, covered with white mycelium at the base of stipe, globose to ovoid perithecia, is macroscopically similar to Cordyceps militaris. Cordyceps changbaiensis is clearly discriminated from other Cordyceps species by its white to orange and branched stromata, clavate to cylindrical fertile apical portion, immersed and globose to ovoid perithecia. Moreover, unbranched, clavate and orange to light red stromata, almond-shaped to ovoid and immersed perithecia separate Cordyceps jingyuetanensis from other Cordyceps species. nrITS, nrLSU and EF-1α sequences were undertaken and phylogenetic trees, based on Maximum Likelihood and Bayesian Inference analysis showed that the three new species clustered with Cordyceps militaris, but formed individual clades, as well as confirmed the results of our morphological study.
Ageing in Place? The Community-Based Integrated Care System in Japan
Authors: Costantini Hiroko
Published: September 2021

Le développement de systèmes de soins intégrés à base communautaire est en cours au Japon. Ces systèmes visent à aider les personnes âgées à continuer à vivre dans des zones où elles ont l’habitude de vivre. Ce document explique l’approche visée en combinant l’intégration de plusieurs parties prenantes, notamment les systèmes de santé et de soins ainsi que les soignants bénévoles et informels, et en mettant l’accent sur la communauté. Étant donné la complexité d’un tel système, il est important d’établir des priorités locales en fonction des besoins et des capacités existantes, ce qui entraîne des variations dans la manière dont ces systèmes sont développés. L’analyse du système permet d’identifier les principaux fondements sociaux et culturels. En effet, si le rôle des aidants familiaux reste central dans le système, il est possible d’envisager d’apporter également un soutien à ces aidants afin de mettre en place un système de soins intégrés à base communautaire plus efficace et plus résistant.
Uniform stability of the relativistic Cucker-Smale model and its application to a mean-field limit
Authors: Ahn Hyunjin , Ha Seung-Yeal , Kim Jeongho
Published: September 2021

We present a uniform(-in-time) stability of the relativistic Cucker-Smale (RCS) model in a suitable framework and study its application to a uniform mean-field limit which lifts earlier classical results for the CS model in a relativistic setting. For this, we first provide a sufficient framework for an exponential flocking for the RCS model in terms of the diameters of state observables, coupling strength and communication weight function, and then we use the obtained exponential flocking estimate to derive a uniform \begin{document}$ \ell_{q,p} $\end{document}-stability of the RCS model under appropriate conditions on initial data and system parameters. As an application of the derived uniform \begin{document}$ \ell_{q,p} $\end{document}-stability estimate, we show that a uniform mean-field limit of the RCS model can be made for some admissible class of solutions uniformly in time. This justifies a formal derivation of the kinetic RCS equation [18] in a rigorous setting.
Partial regularity result for non-autonomous elliptic systems with general growth
Authors: Isernia Teresa , Leone Chiara , Verde Anna
Published: September 2021

In this paper we prove a partial Hölder regularity result for weak solutions \begin{document}$ u:\Omega\to \mathbb{R}^N $\end{document}, \begin{document}$ N\geq 2 $\end{document}, to non-autonomous elliptic systems with general growth of the type:

   \begin{document}$ \begin{equation*} -{\rm{div}} a(x, u, Du) = b(x, u, Du) \quad \;{\rm{ in }}\; \Omega. \end{equation*} $\end{document}

The crucial point is that the operator \begin{document}$ a $\end{document} satisfies very weak regularity properties and a general growth, while the inhomogeneity \begin{document}$ b $\end{document} has a controllable growth.
Politicizing Muslim Mental Health Toward a Decolonial Framework
Authors: Younis Tarek
Published: September 2021

There is a growing recognition that mental illness should be taken more seriously within Muslim communities. In this are emerging trends to Islamicise psychology or psychologise Islam, whereby the former attempts to adapt contemporary psychological practices for Muslims, while the latter endeavours to indigenise and establish a psychology rooted firmly in Islamic traditions. Yet a large body of interdisciplinary works has argued that Muslims are uniquely positioned vis-à-vis Nation-States across the Global North. There is thus a need to underscore the significance of the political which underpins the relationship between ‘Muslim’ and ‘mental health’. The political will be explored by addressing three paradigms and their particular relationship to Muslim mental health: neoliberalism, nationalism and securitisation. I argue that Muslim mental health, irrespective of approach or discipline, is unique in its ability to serve power and ensure Muslims remain productive, loyal and low-risk citizens of the Nation-State. Emerging Muslim mental health models may succeed in their stated objective—alleviate suffering or raise God consciousness—but they do not address the political dimension underlying mental health practice itself. I argue that a movement towards decolonising mental health must remain in constant dialectical resistance with dominant ideological paradigms and be rooted in an interdisciplinary praxis established upon the Islamic paradigm of trusteeship (waqf). This ensures suffering is neither commodified nor compartmentalised outside of the wider Western Muslim experience.
Modification of the Schrödinger equation from Bohr’s theory
Authors: Kohiyama Noboru
Published: September 2021

The mass-energy equation ε = mc2 is obtained from Bohr’s theory. The Schrödinger equation (SE) is modified using this equation. In the hydrogenlike atom, the modified SE is solved for consistency with the eigenvalues of electron’s
energy derived from the Dirac equation. Based on the consistency of their eigenvalues, the microwave emission (e.g., 21 cm radio wave) by the hydrogen atom is expressed.
Einstein’s special relativity violates the constancy of the velocity c of light under one-way conditions and thus contradicts the behavior of electromagnetic radiation
Authors: Ziefle Reiner Georg
Published: September 2021

On Earth, we always measure the constant velocity c of electromagnetic radiation. Einstein assumed the velocity c of light to be constant in all inertial frames and developed his theory of special relativity by considering a light beam that moves back and forth, whereby
he derived transformations between the coordinates of two reference frames: A moving reference frame represented by the coordinate system k and the coordinate system k that is at rest with respect to k. However, by applying Einstein’s theory of relativity, with its
postulates of relativistic time dilation and length contraction, to electromagnetic radiation that moves only in one direction, either in the direction of or in the opposite direction to a moving inertial frame, it is demonstrated that the constancy of the velocity c of light is not
compatible with Einstein’s theory of special relativity. It becomes obvious that Einstein’s relativistic physics must be an unrealistic theory, and consequently, we need an alternative, nonrelativistic, explanation of the constancy of the velocity c of electromagnetic radiation
measured on Earth, and for the special and general “relativistic” phenomena.
Could the sheep-goat effect be the manifestation of attentional-phase dependent mind-matter modulation?
Authors: Piao Daqing
Published: September 2021

The sheep-goat effect of psi cannot be explained without considering mind of specific states. This work speculates mind-matter interaction, as was inferred by many including Erwin Schrödinger, for entertaining an analytically flavored “phenomenological” interpretation of the sheep-goat effect. A fundamental construct of this theory is the operation of mind-matter events in a spatial-temporal-attentional domain, which relaxes to the spatial-temporal domain wherein purely objective events are registered, when the effect of attention vanishes. Attention is quantitated as a nonuniformly interspaced discrete index that depends solely on the number of viable neurons that function in a coherent state for a purpose of the mind. A spatial-attentional “information” domain is assumed to be operable by hinging it with the spatial-temporal “energy” domain along the spatial dimension to form a so-called vivo-dynamic complex. Operations of an event function with respect to the attentional dimension are assigned to assimilate those with respect to the temporal dimension. Domain operators are introduced to specify the domain of temporal or attentional attribution as needed to assess an event and identify the outcome of domain-coupling on the registration of an event. Time-dependent Schrodinger’s equation is then, imperatively, treated as a lower-dimensional case of a higher-dimensional mind-matter-event equation elaborated in the spatial-temporal-attentional complex. The resulted mind-matter-event function defined in the vivo-dynamic complex relaxes to an objective-event function in the spatial-temporal domain at either zeroing of the attention or vanishing of the first-order derivative of the function with respect to the attentional index. The mind-matter-event equation leads to simple traveling-wave-type solutions that are formed by combining the temporal presentation and attentional perception. The auto or cross interaction of the mind-matter event functions then creates “information-energy” coupling terms presumed to be amenable to instrument probing in the spatial-temporal domain as is the objective-event term. The domain-coupling when modulated by the phase difference between the temporal and attentional dimensions is seen to enhance or inhibit the deviation of the event registration in the spatial-temporal domain from its baseline probability. The outcome is thus akin to the sheep-goat effect. The phase-dependency of the event-coupling also elicits why it may be difficult to replicate psi. Such a theoretical manipulation offers novel insights to phenomena that manifest mind-matter interaction.
Pythagorean numbers and the calculation of the masses of the elementary particles
Authors: Arneth Borros
Published: September 2021

We attempt here to calculate the particle masses for all known elementary particles starting from the Rydberg equation and from the Sommerfeld fine structure constant. Remarkably, this is possible. Next, we try to explain why this is possible and what the meaning of the approach seems
to be. Thereby, we find some interesting connections. In addition, we realize that there are two different kinds of mass-charge binding energies in an elementary particle: The internal mass-charge binding energy and the external mass-charge binding energy. These two kinds of mass-charge binding
energies can explain the higher masses of the highly charged brother particles in some of the heavier particle triplets (such as the charmed sigma particles).
Law of physics 20th century scientists overlooked. VI. Cosmic-scale conservation of energy
Authors: Ranzan Conrad
Published: September 2021

The explanation of energy conservation on the cosmic scale requires an understanding of two sets of processes. (1) The set of processes by which electromagnetic energy, the energy of photons in the free state or in the confined state, is gained or is diminished. (2) The set of processes
by which the vacuum, i.e., aether, is generated or is lost—processes by which it emerges/expands and by which it suffers contraction and vanishment. At the heart of the explanation is a straightforward definition of energy at the fundamental level: Any process in which there is a quantitative
change in the units of aether (the discretized medium that permeates all space) constitutes, in and of itself, a manifestation of energy. The workings of the long-overlooked mechanism are revealed. Cosmic-scale energy conservation is maintained by balancing the relevant processes of two distinct
realms—the physical and the subphysical. The physical realm achieves balance by means of a harmony between processes of photon energy gain and energy loss. The subphysical realm achieves balance through the harmony between aether emergence and aether consumption/vanishment. Needless
to say, the implications for cosmology are profound.
Possible Planck-scale physical production mechanisms and consequences of negative energies—Initial formulation
Authors: Bevelacqua J. J.
Published: September 2021

Negative energies within the scope of quantum field theories are often attributed to processes that include loops and vacuum bubbles. The negative energy solutions are a byproduct of virtual particles that have no impact in normal spacetime. However, this paper postulates that virtual
particles can produce physical effects at the Planck-scale.