bluuebunny/crossref_metadata_2025 huggingface dataset:
COVID-19 vaccination literacy, attitude and hesitation towards vaccination and vaccination status of pregnant women
Authors: Kilici Aysegul , Akbulut Sahide
Published: February 2023

The study aims to determine COVID-19 vaccine literacy, attitude and hesitation towards the vaccine, and vaccination status of pregnant women in a rural region. This is a cross-sectional study. It was carried out between June 7 – 7 August 2022. 209 pregnant women were included in the study. The mean score of pregnant women was found to be COVID-19 vaccine literacy 2.5±0.4, attitude 3.1±0.8, and hesitation 7.7±6.6. It was found that 12.4% of the pregnant women had COVID-19 disease in their current pregnancy, and 7.2% of them had COVID-19 disease in the first trimester. It was determined that 34.4% of the pregnancy had a single dose, 30.2% had two doses, and most of them were BioNTech vaccines. Vaccine literacy was determined to be higher in pregnant women who are working, have social security, have a higher income than their expenses and have a master's degree. Those who are married, have social security, and have a female baby have a positive attitude for vaccines. There was a positive significant relationship between COVID-19 vaccine literacy and attitude, and a negative significant relationship between COVID-19 vaccine literacy and hesitancy. It was discovered that COVID-19 vaccine literacy is moderate, vaccination rates are low, and vaccination literacy influences vaccination attitudes and hesitation.
COVID-19-Related life-threatening complications: pneumothorax, pneumo mediastinum and subcutaneous emphysema
Authors: Kutlusoy Sevgi , Aydin Ahmet , Koca Erdinc
Published: February 2023

Complications of COVID-19-related pneumothorax, subcutaneous emphysema, and pneumomediastinum are frequently observed in moderate and severe pneumonia cases. The aim of this study is to determine the incidence and potential risk factors of life-threatening complications such as pneumothorax, pneumo-mediastinum, and subcutaneous emphysema that develop in patients received in the tertiary ICUs of our hospital, which serves as a pandemic hospital and to analyze their relationship with mortality. Patients' demographic characteristics, comorbid diseases, length of hospital stay, day and duration of thoracic tube placement, discharge status, and hospitalization laboratory findings were recorded, and the relationship of these parameters with mortality due to pneumothorax, subcutaneous emphysema, and pneumomediastinum were investigated. Of these patients, 33 had pneumothorax, 12 had pneumomediastinum, and 28 had subcutaneous emphysema. Male and female patients were equally represented, and mortality rates were similar. While the rate of pneumothorax in the study patients was 2.21 %, the rate of all life-threatening sequelae such as pneumothorax, pneumomediastinum, and subcutaneous emphysema was 4.7 %, with a high mortality rate (90 %) in 70 patients with these complications. Patients diagnosed with COVID-19 pneumonia should be constantly monitored for life-threatening complications such as pneumothorax, pneumomediastinum, and subcutaneous emphysema during their long-term follow-up.
Potential cytotoxic effects of borax alone and in combination with irinotecan on YKG1 glioblastoma cell-line
Authors: Yuksel Yasemin , Celik Sefa , Aslan Esra , Tosun Murat , Uysal Mukremin , Pektas Mehmet
Published: February 2023

Glioblastoma Multiforme (GBM), which is a common and primary brain tumor in adults, is an important cause of death worldwide as an aggressive and treatment-resistant cancer tumor. In this cell culture study, the apoptotic and anti-proliferative effects of borax and irinotecan at different doses, alone or in combination, were investigated in the YKG1 cell line. Cytotoxic activities were analyzed by MTT method and TUNEL staining after 24th and 48th hours of incubation with borax administered at doses of 1mg and 3mg per ml; irinotecan 50mM and 100mM. Both irinotecan and borax have been shown to induce apoptosis when used alone, and thus cause anti-proliferation. It was determined that these effects were potentiated by the combined application of the agents. In addition, it was determined that this effect in combined applications was more pronounced after 48 hours and at higher doses. In light of the data obtained, the combination of irinotecan with borax to increase the cytotoxic effect of irinotecan, which is used in many different cancer types, can be tried in further prospective studies.
The affecting factors and prevalence rate of sick building syndrome in healthcare workers
Authors: Karadag Muge , Ecin Seva , Turkkan Sinan , Aytemur Zeynep , Hacievliyagil Suleyman
Published: February 2023

Sick building syndrome (SBS) is defined as symptoms that occur while living or working in a certain building but disappear after moving away from the environment. In this study, we aimed to determine the effects of indoor air pollutants on the health of employees, the prevalence of SBS in healthcare workers at the university hospital, its relationship with environmental and personal factors and the respiratory system. A questionnaire was applied to 951 healthcare workers who agreed to participate in the study. Having at least one general, one mucosal and one skin symptom every week in the last 3 months was accepted as SBS. Temperature, CO and CO2 levels and relative humidity were measured in different areas of the hospital. The prevalence of SBS was 62.1%. There was a statistically significant relationship between SBS and having a chronic disease (p<0.0001), continuous drug use (p=0.005) and the evaluation of the environment as warm (p=0.042). Having a chronic disease (OR=0.426; 95% CI, 0.228–0.797), the environment often being too warm (OR 0.218; 95% CI, 0.084–0.567) or occasionally too bright (OR=0.300; 95% CI, 0.158–0571) and diagnosed by a doctor due to symptoms (OR=3.209; 95% CI, 1.529–6.731) was found to be significant in forward variable selection method and binary logistic regression analysis. In our study, a relationship was found between physical factors such as temperature, humidity and CO2 level of the environment and personal factors such as stress, chronic disease and SBS. SBS can be prevented by control at the source as well as by administrative and engineering interventions among the employees.
Can systemic immune inflammation index measured in the first trimester predict later occurring isolated oligohydramnios?
Authors: Dinc Kemal , Nayki Cenk
Published: February 2023

The aim of our study is to determine whether the first trimester systemic immune inflammation index (SII) and other hematological markers can be useful as new markers of isolated oligohydramnios that may develop later. Two main groups were formed in this retrospective study. In the first group, 57 pregnant women with isolated oligohydramnios in their third trimester (between 28-40 weeks) were included. The control group consisted of 137 healthy pregnant women with a normal amniotic index (AFI) in the third trimester. First trimester and delivery hemogram values and newborn results of all pregnant women in both groups included in the study were noted for statistical comparison. Platelet (261.895+8.04), which is the hematological marker that best predicts IO in the first trimester, was found to be higher than the healthy group (244.390±4.79) (p=0.03). PLR was the best predictor of oligohydramnios in the third trimester. The PLR level was determined as 113,288, and the cut-off value was 64.91%, the upper limit was 95% CI, the specificity was 51.09%, the positive predictive value was 35.58%, and the negative predictive value was 77.78%. The platelet count in the first trimester and the progressive increase in the number of PLR in the third trimester are significantly related in the prediction of oligohydromnus. SII, NLR and PLR measured in the first trimester are useless in predicting isolated oligohydramnios that may develop in the future.
Correlation between COPD duration and abnormality in FEV1, FVC, and BODE index in 100 COPD patients
Authors: Patel Rushi , Gupta Parth , Agrawal Barkha , Patel Tushar , Chauhan Bhavikkumar , Gupta Anil
Published: February 2023

Background: Progression of any disease depends on several factors and one such factor is duration. To determine the progression of chronic obstructive pulmonary disease (COPD), post-bronchodilator forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), and BMI, Obstruction, Dyspnea, Exercise (BODE) index are considered. We have tried to find a correlation between these factors and the duration of disease; to check how these factors fare as the disease progresses.

Aims and Objectives: The aim of the study was to correlate COPD duration with post bronchodilator FEV1, FVC, and BODE index, respectively.

Materials and Methods: A hospital-based and cross-sectional study was conducted at department of respiratory medicine, GCS Medical College, Hospital, and Research Centre, Ahmedabad, Gujarat among COPD patients. Informed consent was obtained from each patient. We analyzed 100 patients of COPD diagnosed by symptoms, presence of risk factors, and spirometry. Detailed clinical history, physical examination, and necessary investigations were conducted in all patients.

Results: Out of which 71 were newly diagnosed cases while 29 were known cases of COPD. On correlating COPD duration with post-bronchodilator FEV1, FVC, and BODE index; we did not find any correlation between them.

Conclusion: We would like to recommend a similar study with a larger population size to arrive at some form of conclusion.
A cross-sectional study of awareness, knowledge, and attitude in pharmacoeconomics related to antibiotic usage in medical postgraduate students
Authors: Muppur Asha , L Sailaja , D Padmavathi , B Vasundra
Published: February 2023

Background: Pharmacoeconomics is one of the burgeoning branch of pharmacology. In the scenario of popping up of various numbers of pharmaceutical companies the prices of various drugs especially antibiotics is varied and this study will help to decrease the expenditure of antibiotics where ever possible.

Aim and Objectives: This study will create awareness in medical postgraduates about prices of antibiotics, which will decrease irrational financial burden on patients and decrease in incidence of antibiotic resistance and adverse effects.

Materials and Methods: The study design is cross-sectional, observational, and questionnaire-based. A preformed questionnaire containing 30 questions was given to 110 medical postgraduate students. Along with demographic data, their awareness, knowledge, and attitude on pharmacoeconomics related to antibiotic usage were analyzed using appropriate statistical tools.

Results: One hundred students were aware of term pharmacoeconomics (90.9%), out of which 58% learned from PG curriculum. Knowledge was considered good when the participants answered 50% of the questions related to terms about pharmacoeconomics. In this context, about 28 female students and 11 male students had good knowledge about pharmacoeconomics (P = 0.02). Students of clinical specialty were more knowledgeable than non-clinical department (P = 0.01). Knowledge about some popular antibiotics prices was questioned. Students were well aware of beta lactum antibiotic prices (60%) compared to other groups. Least awareness was with prices of antifungal drugs. About 63% of students were cost conscious while prescribing antibiotics. The frequency of prescribing an antibiotic suggested by medical representative was about 38%.

Conclusion: The medical postgraduates who participated in this study had a good awareness regarding definition of term pharmacoeconomics. However, knowledge in depth about pharmacoeconomics was hard up. Hence, we recommend to inculcate pharmacoeconomics in 2nd-year MBBS course as a part of pharmacology, where in the students are taught to calculate the expenditure of various treatments. Regular continuing medical education must be conducted to update about pharmacoeconomics related to antibiotic usage. This study will further decrease the cost of treatment in patients.
Evaluation of analgesic properties of Moringa Oleifera and Tinospora Cordifolia leaf extracts on Albino Wistar rats
Authors: Yeldandi Venkateshwarlu , G Sirish , Jillella Aditya , G Swetha , Kadiyala Venkata , A Naga
Published: February 2023

Background: Pain is an unpleasant sensation, that has limitations with available drugs in terms of effectiveness and safety. Plant-based drugs have gained great importance due to their analgesic, anti-inflammatory and anti-pyretic ability, and limited side effects.

Aim and Objectives: The aim of the study was to evaluate the analgesic effect of Moringa oleifera (drumstick tree) and Tinospora cordifolia (guduchi) leaf extracts in rats.

Materials and methods: This prospective study consists 54 healthy Albino Wistar rats of male sex having weights ranging from 150 to 250 g. Normal saline as control and Tramadol was used as standard. Rats were randomly divided into nine groups (n = 6 in each). Commercially available M. oleifera leaf extracts and T. cordifolia leaf extracts were purchased to check the analgesic effect. Analgesic effect was determined by hot plate method after initial dose and by Tail-immersion method after 15 days of interval.

Results: The reaction time of AMO and ATC with doses 100 mg/kg, 200 mg/kg, 400 mg/kg was 4.28, 4.41, 4.74, and 3.96, 4.12, 4.22 at 90 min, respectively. While, tramadol showed high reaction time at 90 (6.41) and 120 min (7.17). The maximum analgesic effect was found at 90 min by hot plate and tail immersion methods in tramadol group than AMO and AMT.

Conclusion: The aqueous leaf extract of M. oleifera and T. cordifolia has similar analgesic properties. The study drugs have not showed any behavioral or lethal adverse effects during the study.
Giant and potentially malignant bullae in a dog
Authors: Roque Caroline , Lima Bruno , Oliveira Guillermo , Nascimento Let
Published: February 2023

Primary lung neoplasms are represented by solid, solitary or multiple formations. Blisters are pulmonary emphysemas larger than 1cm, present complete destruction of lung tissue, resulting from dilation, destruction and coalescence of adjacent alveoli, filled with air, located in the subpleural space, surrounded by connective tissue septa, between the lung and the layer of the visceral pleura. Bullaes occupy more than 30% and surgical removal is recommended. The present clinical case reports a 14-year-old female dog, of mixed breed, with an increase in the coughs frequency, fatigue and exercise intolerance. A chest X-ray was taken, a large emphysematous cystic area was found, with thickened and irregular walls located in the left caudal pulmonary lobe, which measured 8cm x 7.5cm x 3cm, and rejected the bronchial branch corresponding to the left caudal pulmonary lobe, in addition to thickening of the bronchial walls, compatible with bronchopathy. The tomographic examination of the cavity showed an air content structure, oval to round in shape, with irregular thick hyperattenuating walls measuring approximately 0.4 cm in thickness, occupying more than 30% of the left hemithorax, and pulmonary lobectomy was chosen. Histopathology confirmed the diagnosis of bronchoalveolar adenocarcinoma, with the presence of sparse areas of necrosis and dystrophic calcification. Concluding that the tomographic exam is of great importance, because only through it, it is possible to evaluate if there is lymph node or pleural involvement or the presence of small metastasis foci. There is indication for surgery and histopathological examination of the piece for a definitive diagnosis.
Attitudes and barriers of pregnant women toward prenatal oral health care at antenatal centers of Mosul City, Iraq
Authors: Hashim Abdulrahman , Ayed Alaa , Aldeen Najwa , Ali Shahad
Published: February 2023

Objective: To evaluate pregnant women's attitudes on oral health and the obstacles to promoting it.
Methodology: This descriptive, cross-sectional study was carried out from 10th of September, 2022 to 20th of October, 2022. It included 155 pregnant ladies chosen using simple random sampling, and data were collected from 6 antenatal care centers in Mosul city. We used a structured interviewing questionnaire.
Results: Average age of women was 28 years and 54.8% agreed that maintaining good oral health during pregnancy affects the health of the fetus. More than 54% said their greatest obstacle to promoting good oral health during pregnancy was their fear that dental treatments will harm the fetus.
Conclusion: Most of the study participants had a good attitude toward improving pregnant women's oral health. However, they were afraid that dental treatments will harm their fetuses.
Epidemiology of leukemia among children in Nineveh Province, Iraq
Authors: Ibrahim Rian , Idrees Nada , Younis Nasir
Published: February 2023

Objective: To determine the prevalence of leukemia among children during 2018-2021 in Mosul city.
Methodology: This retrospective study was conducted on leukemia patients in Oncology Center at Ibn Al-Atheer Hospital from 10th January to 30th April 2022. Data were collected from patients’ records.
Results: Out of 153 patients, 99 (64.8%) were males and 54 (35.2%) females. The disease was found in children of school age more than in the rest of the ages and more males and those belonging to urban areas were affected. Acute lymphatic leukemia was commonest form found.
Conclusion: The prevalence of the disease is very high and is constantly increasing. The incidence of the disease in school-age children is relatively high.
Knowledge' assessment of insulin self-administration in diabetic patients at Diabetes Health Centers, Baghdad, Iraq
Authors: Salih Shakir , Badr Raheem , Jissir Saad
Published: February 2023

Objective: To assess knowledge regarding insulin self-administration among diabetic patients in Baghdad City.
Methodology: This descriptive cross-sectional study included a sample of 90 patients with diabetes mellitus on insulin therapy attending clinic of outpatients at National Diabetes Center of Al-Mustansiriya University and Specialized Center for Endocrine Disorders and Diabetes in Al-Russafa Health Directorate. The data were collected from March 15 to April 30, 2021.
Results: The study’s participants had average information about diabetes, insulin and insulin self-administration. They got information from health personnel, personal experience, relatives, and internet. More than half of participants (53.3%) had normal level of knowledge about insulin self-administration.
Conclusion: This study showed differences in patients’ knowledge about insulin self-administration. Focusing on their knowledge's improvement is essential to enhance their practice. Health education must be provided by physicians through counselling patients at each follow up visit.
Selection of Prioritized Healthy Family Indicators, Using the Difficulty-Usefulness Pyramid (DUP)
Authors: Hardjito Koekoeh , Rahmaningtyas Indah , Nugroho Heru
Published: February 2023

Objective: This study aimed to select Healthy Family Indicators in order of priority, using the Difficulty-Usefulness Pyramid (DUP).
Methodology: This study involved families in Indonesia who were selected using the snowball sampling technique. Data on difficulty and usefulness were collected through filling out an online-questionnaire that included 12 indicators of a healthy family, then analyzed and presented in the form of a pyramid.
Results: The usefulness score tends to be homogeneous, with a mean score of 9.41 (very useful), while the difficulty score tends to be heterogeneous, with a mean score of -2.17 (easy). The most difficult indicator to achieve was “family members do not smoke.”
Conclusion: All indicators of a healthy family are felt to be very useful for families, with the highest level of difficulty in indicators of non-smoking behavior; while the 3 main priorities are non-smoking behavior, mental disorders treatment, and exclusive breastfeeding.
Problem of antibiotic resistance in urinary tract infection in ALdiwaniyah city, Iraq
Authors: Alqani Vian , Meizel Mudhfar , ALfuadi Anmar
Published: February 2023

Objective: To identify the most common UTI-causing bacteria in the study samples and to identify the most culture-sensitive antibiotics.
Methodology: The study was conducted at Adiwahiyah Teaching Hospital in Iraq's mid-Euphrates area from January 15, 2018 to September 2, 2019. The research included 400 Iraqi patients ages 2 to 85 with UTI symptoms.
Results: E. coli was sensitive to imipenem, meropenem, amikacin, and chloramphenicol. Klebsiella pneumoneae was sensitive to amikacin, imipenem, and meropenem. Enterobacter aerogenes was sensitive to imipenem, chloramphenicol, amikacin, and meropenem. Morganella morganii was sensitive to imipenem, meropenem, amikacin, and chloramphenicol. Trimethoprim-sulphamethoxazole, trimethoprim, tetracycline, and doxycycline were effective against Proteus mirabilis. Imipenem and meropenem were effective against Pantoea agglomerans. Amikacin, imipenem, and meropenem were effective against Providencia stuartii. Serratia marcescens was susceptible to trimethoprim-sulphamethoxazole, trimethoprim, amikacin, chloramphenicol, imipenem, and meropenem.
Conclusion: In the current study, in order of frequency, the most frequently isolated bacteria were E. coli, followed by Staph aureus. The study showed that the three best antibiotics for almost all isolated bacteria were imipenem, meropenem and amikacin with very minor exceptions.
Jordanian nurses' knowledge of Evidence-Based Practice
Authors: Saleh Ahmad
Published: February 2023

Objective: To evaluate Jordanian nurses’ knowledge about evidenced based practice.
Methodology: This cross-sectional included 120 Jordanian nurses from one private hospital in Amman, Jordan. Evidenced-based practice knowledge tool was used to gain data An informed consent was obtained from all nurses. Of the 120 nurses, 100 responded, resulting in a response rate of 83%.
Results: Out of 100 respondents, 75 (75%) nurses were female and average age of 26±2 years. The average score of knowledge regarding evidenced based practice was low at 1.2±1 out of 10.
Conclusion: Knowledge of nurses regarding evidenced based practice was low. An evaluation is needed, in order to improve knowledge and skills of nurses.
Assessment of nutritional habits among Mosul University Students regarding breakfast
Authors: Mohammad Fatema , Noori Lara , Younis Nasir
Published: February 2023

Objectives: To assess nutritional habits among Mosul University students regarding breakfast.
Methods: This descriptive study was conducted from the 1stoctuber of to the 1st of November 2022 and included 200 students aged between 18-26 years from the University of Mosul. Data were gathered by having students fill out a questionnaire in the classroom and doing an interview with them that included asking about their personal information.
Results: The findings reveal that breakfast was an important meal during the day and accounted for 55% with a benefit of 90%. Sixty-eight percent students were feeling active, energized, and focused when eating breakfast, 59% knew the disadvantages of not eating breakfast and 57.5% felt hungry during working hours because they didn′t eat breakfast. The study found that 75% students drank tea or coffee with breakfast, 61.5% ate dairy products, 55% ate bread and pastries, and 46.5% ate eggs at breakfast.
Conclusions: The study found that shortage of time, lack of appetite, and skipping of breakfast were the main reasons for not eating this meal.
The Effect of Dietary Protein Quality on Short-Term Satiety and Daily Energy Intake
Authors: Arslan Nurgul , Cakiroglu Funda , Yaprak Bulent
Published: February 2023

Introduction: Some protein structures in the structure of foods are known to provide long-lasting satiety. Depending on the food source, this period of satiety can be shortened or lengthened. It has been reported that in diets for treating obesity in which long-term satiety is a goal, animal-derived proteins can help people feel fuller for longer. This study aimed to examine the effects on satiety markers after breakfast of consuming breakfast foods prepared with different protein sources.
Materials and Methods: The study included 40 participants but concluded with 39 participants. Sixteen males and 23 females participated in the research. The participants in the study were randomly assigned to begin the investigation. After 12 hours of fasting, the study participants were offered two breakfasts on separate days. Two distinct breakfasts consisting of foods of animal origin and foods of vegetable origin were served.
Results: The breakfasts had similar calories, protein, fat, carbohydrates, and fiber. Before and after breakfast, a VAS scale with seven satiety markers was created and applied. The scale was applied 0 minutes before breakfast, 30 minutes, 60 minutes, 120 minutes, and 180 minutes after breakfast. After breakfast, it was observed that the satiety markers of animal origin had a longer duration and higher scores than those of plant origin.
Conclusion: In cases where energy restriction is necessary, it has been determined that increasing the protein quality in the foods consumed can provide long-term satiety regardless of the amount consumed.
The Relationship of Endocan to Disease Severity in Psoriasis: Effect of Endocan on VGEF, CXCL12 and NGF Levels
Authors: Yurekli Ugur , Akkus Muhammet
Published: February 2023

Introduction: Psoriasis is a chronic disease accompanied by angiogenesis and inflammation, significantly affecting patients' quality of life. Its pathophysiology has not been fully elucidated. Endocan, VEGF, CXCL12, and NGF are molecules involved in inflammation and angiogenesis. There is a restricted size of studies investigating the relationship of these molecules with psoriasis. The study aims to determine the levels of endocan, VGEF, CXCL12, and NGF in psoriasis patients, identify the relationship of these parameters with illness intensity and define the correlation between serum endocan level and VGEF, CXCL12, and NGF.
Materials and Methods: In this study, endocan, VGEF, CXCL12, and NGF levels were determined in the serum of 100 healthy persons and 94 psoriasis patients using the ELISA method and compared with the control group. Illness violence was grouped with the Psoriasis Area and Severity Index (PASI); Endocan, VGEF, CXCL12, and NGF levels were compared according to disease severity. Correlation analysis was performed between endocan and VGEF, CXCL12, and NGF in psoriasis.
Results: Endocan, VGEF, CXCL12, and NGF levels were high in psoriasis. It was determined that as the severity of the disease increased, the serum levels of these parameters increased. A moderate positive correlation was found between Endocan and CXCL12 and NGF.
Conclusion: Serum Endocan and NGF levels increase with disease severity; Endocan and NGF can be used as target molecules in psoriasis treatment.
Comparison of Midterm and Long-Term Effects of Cord Protection Methods on Left Ventricular Function in Mitral Valve Replacement Surgery
Authors: Arslanoglu Yavuz , Deniz Hayati , Ustunsoy Hasim
Published: February 2023

Introduction: Our study aimed to determine the effects of cord protection methods applied in Mitral valve replacement (MVR) surgery on left ventricular function.
Materials and Methods: MVR surgery was performed on 634 patients using either single or combined procedures. Of these patients, 358 (56.5%) underwent conventional MVR surgery, 121 (19.1%) underwent total chordal protection, and 155 (24.4%) underwent posterior chordal preservation. All patients were evaluated as class 3 and 4 according to the New York functional classification (NYHA). Left ventricular diastolic end-diameter (SVDSD), left ventricular systolic end-diameter (SVSSD), end-diastolic volume (EDV), end-systolic volume (ESV), and ejection fraction (EF) were compared between groups.
Results: The degree of valve insufficiency was 3 and 4 in patients with mitral insufficiency. The mortality risk for patients undergoing conventional surgical operations was 4.257 times higher (OR:4.25; 95%CI:1.22-14.76). The study showed positive effects of chordal protection on the clinical status and echocardiographic parameters of undergoing MVR surgery (p<0.01).
Conclusion: We believe cord protection methods positively affect left ventricular function after MVR. In particular, total chordal protection will positively affect left ventricular function.
MICROESTRUTURA, DENSIFICAÇÃO E MICRODUREZA DE PASTILHAS DE HIDRÓXIAPATITA OBTIDA A PARTIR DE ESCAMA DE PEIXE PRENSADAS E SINTERIZADAS
Authors: Botão Camila Alves Pelicarto da Silva , Júnior Eustáquio de Souza Baêta , Aguilar Marilza Sampaio , Moura Francisco José , Aguilera Letícia dos Santos , De Campos José Brant
Published: February 2023

As escamas de peixe podem ser utilizadas para a obtenção de Hidróxiapatitas (HAp) por rotas químicas simples, mostrando o seu potencial como biomaterial de interesse nas indústrias farmaucêtica, cosmética e biomédica. Estudos in vitro com HAp produzida por escamas de Tilápia, Aruanã e Pirarucu tem apresentado bons resultados de biocompatibilidade. Muito desenvolvimento ainda pode ser feito na utilização de HAp, e a caracterização estrutural e microestrutural é importante conhecer propriedades de amostras para sua aplicação. Este trabalho visa buscar uma condição que promova maior densificação e microdureza, comparando pastilhas produzidas com HAp obtidas de escamas de Pirarucu em duas condições, sem tratamento térmico e com tratamento térmico anterior à sinterização. Foram realizadas análises através de Microscopia Eletrônica de Varredura para verificar a morfologia dos pós e das pastilhas sinterizadas, Difração de Raios-X para ver se houve mudança de fases na sinterização. Medidas de densidade e densificação das pastilhas foram realizadas pelo método de Arquimedes e a microdureza Vickers foi utilizada para verificar a dureza das pastilhas produzidas. Os resultados mostram que a pastilha de HAp sem tratamento térmico apresentou maior densificação, menor porosidade e maior microdureza e não foi verificada composição de fases distintas entre as amostras.
ACOLHE APS: CAPACITANDO AGENTES COMUNITÁRIOS EM SAÚDE MENTAL NO MUNICÍPIO DE IGUATU-CE
Authors: Dos Santos Jomábia Cristina Gonçalves , Araújo Denise da Silva , Alencar Frederico Santos , Vieira Camilla Araújo Lopes
Published: February 2023

O presente trabalho apresenta a experiência de elaboração e facilitação da ação de extensão no formato de curso, intitulado Acolhe APS, vinculado ao Projeto de Extensão denominado Laboratório de Clínica Sujeito e Políticas Públicas (CLIPSUS) e ao Programa de Pós-Graduação Profissional em Psicologia e Políticas Públicas da Universidade Federal do Ceará – PPGPPPP, campus Sobral. O objetivo do Acolhe APS foi desenvolver um curso de capacitação profissional sobre o uso de tecnologias leves em saúde e promoção da saúde mental para Agentes Comunitários de Saúde do Município de Iguatu, Ceará. O conteúdo do curso foi formulado a partir de quatro grupos focais previamente efetivados com 26 agentes comunitários, entre agosto e setembro de 2021. Com carga horária de 20h/a, o curso foi dividido em um encontro presencial e duas atividades assíncronas, realizadas durante o mês de maio de 2022. Se inscreveram para a capacitação, 103 ACS, destes, 71 participaram do encontro presencial. O conteúdo programático teve entre suas temáticas: Políticas de Saúde Mental na Atenção Primária à Saúde (APS), Promoção em Saúde Mental e Tecnologias leves em saúde. Dentre as reflexões elencadas durante a capacitação destacaram-se: o desmonte da política de saúde mental e suas repercussões no cuidado ofertado pelos profissionais da APS, estratégias de trabalho coletivas para promover saúde mental, e a saúde mental dos trabalhadores da atenção primária na pandemia Covid19. Através de uma metodologia dialógica, os participantes puderam trocar experiências sobre as possibilidades de cuidado em saúde mental na APS. Ao final, 66 participantes cumpriram a carga horária mínima exigida do curso, e foram certificados, avaliando positivamente a capacitação. Dentre as sugestões de melhorias para o Acolhe APS, os ACS indicaram que o mesmo fosse realizado com as demais categorias profissionais, e com um número maior de encontros presenciais.
Tradisionalisasi Pondok Pesantren Modern Al-Falah Dago Kota Bandung
Authors: Komala Ela , Supriadi Yusep
Published: February 2023

Perkembangan modernisasi, telah banyak membawa perubahan-perubahan dalam dunia pendidikan, termasuk pesantren sebagai lembaga pendidikan Islam. Karena modernisasi, pesantren tradisional kemudian banyak melakukan pembaruan menjadi pesantren modern, ada juga yang bertahan. Untuk menelusuri tradisionalisasi di Pondok Pesantren Modern Al-Falah, peneliti mengunakan metode penelitian pendekatan analisis deskriptif kualitatif. Teknik pengumpulan data dilakukan dengan observasi, wawancara dan studi kepustakaan serta dokumentasi. Hasil penelitian menunjukkan bahwa sistem pendidikan Pondok Pesantren Al-Falah  merupakan kombinasi antara unsur tradisionalisme dan modernisasi. Perubahan sistem pendidikan pondok pesantren salafiyah di satu sisi merupakan proses linear, artinya berbagai sistem pendidikan telah diperbarui sebagai respon terhadap modernisasi. Namun di sisi lain  tetap memegang tradisi lama pesantren tradisional (sebagai warisan masa lalu yang telah mengakar dalam diri pesantren). Maka, pada hakikatnya perubahan yang terjadi pada sistem pendidikan pondok pesantren tersebut merupakan proses perubahan menuju terciptanya pendidikan integral.
Artificial Intelligence in Communication with Music Fans: An Example from South Korea
Authors: Polak Marija , Kolić Stanić Matilda , Togonal Marijana
Published: February 2023

According to Kotler, Kartajaya, and Setiawan, there are five components of marketing 5.0: it is data-driven, predictive, contextual, augmented, and agile. This paper uses the case study method to investigate the presence of the 5.0 marketing components in promotional strategies employed by the South Korean popular music industry. The paper explores promotional strategies used by the BTS music group in particular. The group uses the 5.0 marketing method in its promotional strategies, especially in communication with the fans, and such communication thus enters the field of public relations. The case study analysis also indicates the use of data-driven marketing and predictive analytics, which are achieved using artificial intelligence. Additionally, elements of contextual marketing were used to improve the consumer experience, and augmented marketing was utilized to facilitate business, especially for front office staff. Finally, the analysis of BTS's promotional strategies shows a focus on innovation and flexibility, which are elements of agile marketing.
Leadership in an Ageing Society and the Brain: Applying Neuroscience to Leadership
Authors: Debelak Katja , Penger Sandra , Grah Barbara
Published: February 2023

“What makes a great leader?” This question has been on the minds of scientists, philosophers, professionals, and others around the globe for centuries. Many theories and models have been proposed to answer the question, but none has fully captured leadership as a dynamic and constantly evolving attitude. In the last 20 years, technological advancements have helped neuroscientists understand the human brain better. With the help of ground-breaking insights in neuroscience, the leadership enigma has a convincing answer rooted in a specific and very tangible source: the brain. This paper aims to increase awareness around the impact of the brain on leadership behaviour in an aging society by presenting secondary research of available scientific theory. In particular, this paper aims to provide an overview and assess the brain-based leadership models and recent approaches to highlight the possible ways to boost the leadership brain and enhance performance. The paper also points out the ethical issues arising from brain enhancement in leadership and leaders' awareness of the possible broad social consequences that neuro leadership might bring.
A Case Study of Investor R&D Evaluation using Game Theory
Authors: Georgiou Andreas
Published: February 2023

This paper aims to identify an optimal investment strategy in cases of high-intensity R&D private micro entities. A game theory matrix is constructed using publicly available empirical data extracted from the financial statements of an R&D-intensive private micro-entity. The game theory matrix attempts to estimate the effect of the discretionary managerial choice to capitalise or expense the development cost of internally generated intangible assets; investors' risk appetite could be affected by the capitalisation signalling. The investment strategies are classified based on their risk into three categories. High risk is represented by equity. Medium risk is represented by long-term debt, and low risk is represented by short-term debt. The game theory matrix results indicate that in similar situations, the dominant strategy is the medium-risk approach through long-term debt. This strategy must be confirmed by solving more game theory matrices based on similar R&D-intensive firms. However, it is an easily constructed advisory indicator for retail investors considering investing in unaudited small private entities. They could use it to identify an optimal investment strategy when uncertain of the genuine intangible asset prospects signaled via development cost capitalization.
Impact of Additive Manufacturing on the Strategic Alignment of Business Processes in the Logistics Industry in Europe
Authors: Dalaqmeh Nadia , Irsa Wolfram
Published: February 2023

The logistics industry in Europe is under constant scrutiny due to the impact of digitalizing business processes and the globalization of competing markets, especially China and the USA. Therefore, the constant optimization of corporate legacy processes and, subsequently, the reduction of logistics costs play a crucial role. The constant development of innovative solutions keeps the technological edge to stay ahead of the global competition. 3D printing technology, or additive manufacturing, represents a possibility for creating innovative complex geometries, which cannot be realized with conventional subtractive manufacturing processes. Furthermore, additive manufacturing contributes to process optimization and lower logistics costs. With the appropriate strategy, the application of additive manufacturing increases customer satisfaction with new opportunities for expansion into leading business areas with higher margins. The research of the paper examines expert statements in two balanced scorecard strategies, which include (1) corresponding key performance indicators for measurement of target achievement, (2) measurement of the realization of the defined targets, and (3) possible customer applications for 3D printing technologies. These suggestions serve as a point of reference for various organizations in the logistics industry. In addition, additive manufacturing coincides with the advances in Industry 4.0 to achieve optimal results. As the industry continues to develop further, the European logistics industry has all prerequisites to prevail in a competitive global market.
Application of Digital Images and Corresponding Image Retrieval Paradigm
Authors: Ivasic-Kos Marina
Published: February 2023

We live in a world where digital images are constantly generated during our daily activities, whether private or business. They play an important role in our private life, showing important moments, people, places, or events and keeping their memory. Images are unavoidable in business, especially in digital marketing, web sales, social networks, medicine, security, and education. In general, images contribute to a better understanding of the message, increase the attractiveness of textual content, provide a better user experience, and can convey emotion quickly. The key advantage of the image is that very often, even a cursory glance at the image is enough to convey a message and arouse emotion and interest. But with the increase in digital image numbers, storage, organization, and retrieval problems arise. The paper describes the importance of images in different areas of application and different image retrieval paradigms that include text-based, content-based, and combined approaches. Also, the most popular image search tools and cloud storage services are compared and discussed. The conclusion comments on the applicability of existing approaches to image searches in different application domains and highlights the advantages and disadvantages of each of the approaches.
The Role of 5G and IoT in Smart Cities
Authors: Car Tomislav , Pilepić Stifanich Ljubica , Kovačić Nataša
Published: February 2023

Smart cities, one of the key application areas of 5G and IoT technologies, have at their core the goal of improving quality of life, creating collaborative solutions, and addressing resource constraints. Examples of some of the many services integrated into the network of a typical smart city are related to smart health, smart transportation, smart buildings, smart hotels, smart industry, smart universities, etc. The new era of wireless mobile telecommunication technology and the IoT ecosystem is driving the opportunities for smart cities to not only solve existing problems but also create new services and functionalities that are out of the box and invisible to the end user. The main objective of this paper is to explore the role of 5G and IoT in smart cities. The market environment, key business developments, and trends related to the key smart cities’ enablers, IoT and 5G, are presented. An in-depth literature review followed by a discussion is substantiated with synthesised research findings on the current development, 5G coverage, use and deployment of IoT in smart cities, and forecasting the evolution of its application in smart cities.
The Role of Social Responsibility in Company Strategy
Authors: Barić Andrija
Published: February 2023

Social responsibility is an irreplaceable concept in the modern global economic network. As the concept of social responsibility "matured" in business and science, an increasing number of investors have recognized the benefits of conducting socially and environmentally conscious business and are encouraging the management and other stakeholder groups to implement socially responsible activities to achieve strategic goals. Strategic implementation of socially responsible activities opens up the space for creating a market position that competitors can hardly reach. They would have to successfully imitate the whole spectrum, not just a single socially responsible activity. This paper aims to discuss the relationship between the implementation of social responsibility and company strategy in light of previous research. Sustainable competitive advantage and a positive business result stem from a quality strategy adhered to by all organizational levels in the company. A good link between corporate strategy and the concept of social responsibility is a prerequisite for achieving long-term business sustainability in the global economic network. Based on the above, social responsibility is considered an important strategic element.
Extreme Waves Conditions at the Entrance of Constanta Port
Authors:   National Institute for Marine Research and Development “Grigore Antipa”, 300 Mamaia Blvd, 900581, Constanta, Romania, Vlăsceanu Elena , Omer Ichinur ,   Faculty of Civil Engineering,” Ovidius” University of Constanta, 22 B Unirii Street, RO-900524, Constanta, Romania, Niculescu Dragoș ,   National Institute for Marine Research and Development “Grigore Antipa”, 300 Mamaia Blvd, 900581, Constanta, Romania, Marin Dragoș ,   National Institute for Marine Research and Development “Grigore Antipa”, 300 Mamaia Blvd, 900581, Constanta, Romania, Mateescu Răzvan ,   1. National Institute for Marine Research and Development “Grigore Antipa”, 300 Mamaia Blvd, 900581, Constanta, Romania 3. Department of Mechanical Engineering, Faculty of Engineering, “Dunarea de Jos” University of Galati, 47 Domneasca Street, 800008 Galati, Romania, Rusu Liliana ,   Department of Mechanical Engineering, Faculty of Engineering, “Dunarea de Jos” University of Galati, 47 Domneasca Street, 800008 Galati, Romania
Published: February 2023

The aim of this study is to obtain the extreme wave propagation at the entrance of Constanta maritime port area, as well as the impacts on port operations. The wave propagation modeling took into account the bathymetry of the harbor in the area of interest, updated port extensions layout, measurements and digitized bathymetric maps. For the selected offshore waves directions, considered for the harbor entrance area, the incident waves of maximum impact and the peak period values corresponding to the extreme heights of the significant wave at different return periods were calculated. For this study it was used a mild-slope wave propagation numerical model. The model provided quantitative evaluation of the vulnerability induced by the wave agitation on the port developing areas and an overview on hydrodynamic conditions which are the basis for various shelter facilities developments in Constanta Harbor, in extreme events circumstances.
Assessment of the Geomorphological and Sedimentological Changes in Mamaia Sector after the Implementation of the Coastal Protection Measures
Authors:   National Institute for Marine Research and Development “Grigore Antipa”, 300 Mamaia Blvd, 900581, Constanta, Romania, Marin Dragoș , Petrișoaia Silică ,   National Institute for Marine Research and Development “Grigore Antipa”, 300 Mamaia Blvd, 900581, Constanta, Romania, Spînu Alina ,   National Institute for Marine Research and Development “Grigore Antipa”, 300 Mamaia Blvd, 900581, Constanta, Romania, Mateescu Răzvan ,   National Institute for Marine Research and Development “Grigore Antipa”, 300 Mamaia Blvd, 900581, Constanta, Romania, Diaconeasa Dănuț ,   National Institute for Marine Research and Development “Grigore Antipa”, 300 Mamaia Blvd, 900581, Constanta, Romania, Vespremeanu Emil ,   University of Bucharest, Faculty of Geography, 1 Nicolae Bălcescu Blvd, 010041, Bucharest, Romania
Published: February 2023

"The paper analyses the changes in the beach sector of Mamaia resort from a geomorphological and sedimentological point of view in the context of coastal protection works carried out in 2014-2015 and 2021 (measures to reduce wave energy, beach protection with structures to stabilize the sand and beach nourishment). The Mamaia sector, with a length of about 12 km, is geomorphologically constituted mainly by sandy barrier of Lake Siutghiol representing a transition unit between the northern unit (deltaic and lagoon shore) and the southern unit (small pocket rocks-beaches in front, separated by small coastal sandbars). From an economic point of view, the sector is important for coastal tourism both in terms of the number of tourists and the existing of infrastructure generating significant revenues. Since the 1950s, the sector has been severely affected by the construction of the dikes of the Midia Port in the north, which have affected the longitudinal transport of sediments and accentuated the erosion of the submerged and backshore beach. To counteract the effects of erosion, a longitudinal and transversal coastal protection system was built between 1960 and 1990, which proved to be ineffective in the long term. The data collected in the field (topographic profiles of the backshore, shoreline, sediment samples) before and after the recent coastal protection works were processed using a dedicated software (ArcGIS 10.x and Gradistat v8) and represented in the form of maps and graphics. The spatial analysis highlighted the modification of the coastal system components, the trends of the beach evolution in longitudinal and transversal profile and the changes in the structure and distribution of sediments determined by the impact of the coastal protection works."