bluuebunny/crossref_metadata_2025 huggingface dataset:
Visual loss after long-haul flight
Authors: Abdul Ghani Nurliyana Ain , Mohd Abdullah Azlindarita Aisyah Binti , Abdul Hamid Shamsiah , Yuhana Muhamad Yazli , Ramli Norlina
Published: October 2020

Background:

Deep cerebral venous sinus thrombosis is a reversible yet potentially serious thromboembolic event. A number of reports suggest a relationship between long-haul flights and thromboembolic events, mainly deep venous thrombosis (DVT) and pulmonary embolism (PE). It is rarely reported to cause deep cerebral venous sinus thrombosis. We report a case of a bilateral papilledema after long-haul flight secondary to deep cerebral venous sinus thrombosis with subsequent complete recovery post corticosteroid and anticoagulant therapy.

Case:

A case of a 21-year-old woman with no known medical illness who presented with gradual painless bilateral visual loss is described. She had a history of travelling on a long-haul flight 3 weeks prior to presentation. Examination showed presence of bilateral papilloedema, no vitritis, choroiditis and retinitis. Blood investigations showed raised international normalised ratio (INR). Otherwise, workup for infectious causes of optic disc swelling, connective tissue disease screening were normal. Magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) of the brain showed loss of flow signal in the right transverse sinus and the left sigmoid sinus. Blood workup for preexisting hypercoagulable state was normal. She was diagnosed with deep cerebral venous sinus thrombosis and showed complete recovery with oral corticosteroid and anticoagulant therapy.

Conclusion:

Deep cerebral venous sinus thrombosis is a potentially serious consequence of long-haul flights. A high index of suspicion along with radiological techniques is needed for early detection and initiation of anticoagulation for this reversible condition.
Should we employ preoperative templating in hip hemiarthroplasty after femoral neck fracture? A nested case-control study
Authors: Pujol Oriol , Carrasco María G , Vicente Matías , Mimendia Iñaki , García Yaiza , Selga Jordi , Barro Víctor
Published: October 2020

Introduction:

Dislocation following hip hemiarthroplasty is a serious complication. It remains unclear if acetabular morphology is associated with a higher risk of dislocation. The aim of our study was to investigate whether there are differences in hip morphology radiological parameters between patients who have suffered a dislocation episode, and those who have not suffered a dislocation.

Material and methods:

Between January 2015 and December 2018, a nested case-control study was performed. From 707 patients who underwent hip hemiarthroplasty because of femoral neck fracture, 50 patients (50 hips) suffered an episode of dislocation. They were randomly matched with 94 patients (100 hips) without dislocation (ratio 1:2). Clinical data regarding demographics, medical comorbidities and surgical and radiological parameters were studied.

Results:

Statistically significantly smaller lateral centre-edge angle (LCEA) and femoral offset (FO) and greater Tönnis angle were found in the dislocation group. No differences in acetabular angle were seen. Neurological impairment prevalence was statistically significantly higher in patients who suffered a dislocation (60% vs. 44%, p = 0.011).

Conclusions:

The current study suggests that a smaller LCEA and FO, a greater TA, and neurological impairment could be related to a higher risk of hip hemiarthroplasty dislocation after femoral neck fracture in the elderly. We consider that preoperative templating could be helpful in identifying abnormal parameters and carefully planning surgery could lead to changes in treatment strategy, such as choosing a dual-mobility total hip arthroplasty.
Long peripheral catheters and midline catheters: Insights from a survey of vascular access specialists
Authors: Qin Kirby R , Pittiruti Mauro , Nataraja Ramesh M , Pacilli Maurizio
Published: October 2020

Background:

Peripheral intravenous access is no longer limited to the standard intravenous catheter (cannula). Devices varying in length, material and insertion technique, are increasingly accessible. There is substantial variability surrounding the nomenclature and use of these devices in the literature. We wished to understand the attitude of vascular access specialists towards the nomenclature and use of peripheral intravenous catheters (PIVCs), long peripheral catheters (LPCs) and midline catheters (MCs).

Methods:

A 15-question electronic survey was sent to members of the Association of Vascular Access (AVA) regarding the nomenclature and use of PIVCs, LPCs and MCs.

Results:

A total of 228 participants completed the survey. Approximately two-thirds of respondents use LPCs (65.8%) and MCs (71.9%) in their clinical practice. The most common indication for LPCs was difficult venous access (56.5%), while the most common indication for MCs was medium-term (1–4 weeks) intravenous therapy (62.7%). The majority of participants (57.9%) agreed with the following classification of peripheral intravenous devices: PIVCs: 2 to 6 cm in length, terminating distal to the axilla; LPCs: 6 to 15 cm in length, terminating distal to the axilla; MCs: 15–25 cm in length, terminating in the axilla. Participants suggested that the length of the catheter should be considered a general recommendation, as LPCs and MCs should be primarily differentiated by tip location.

Conclusions:

The majority of vascular access specialists from AVA have incorporated LPCs and MCs into their repertoire of peripheral venous access tools. We envisage that their use will increase as the clinical community becomes more familiar with these devices.
Antioxidative and Metabolic Effects of Lactobacillus plantarum, Inulin, and Their Synbiotic on the Hypothalamus and Serum of Healthy Rats
Authors: Hosseinifard Elaheh-Sadat , Bavafa-Valenlia Khadijeh , Saghafi-Asl Maryam , Morshedi Mohammad
Published: October 2020

Nowadays, much attention has been paid to the link between gut microbiota and brain. The beneficial metabolic effects of probiotics and prebiotics in several diseases such as diabetes and obesity have been reported. However, studies bridging the association of gut microbiome with brain function in healthy states are rare. Therefore, it was hypothesized that the administration of Lactobacillus plantarum ( L plantarum) and inulin may affect serum and hypothalamic metabolic parameters as well as oxidative markers in healthy male rats. Daily L plantarum (107 CFU/mL) and inulin (5% of daily food weight) or their combination (synbiotic) was given to healthy rats. Then, serum and hypothalamic levels of leptin, insulin, and oxidative markers were measured. Administration of synbiotic for 8 weeks led to significant changes in serum levels of high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol, low-density lipoprotein/high-density lipoprotein ratio, triglyceride, and total cholesterol. The intake of synbiotic also resulted in a significantly reduced hypothalamic level of malondialdehyde and increased hypothalamic superoxide dismutase (SOD). Also, L plantarum could significantly increase hypothalamic SOD level. Furthermore, synbiotic administration insignificantly increased the hypothalamic and serum levels of insulin and leptin. These findings suggest that the synbiotic could significantly improve oxidative markers and lipid profile in healthy rats. Therefore, simultaneous intake of L plantarum and inulin appears to be more effective in the amelioration of metabolic and oxidative parameters.
Hardness, friction and wear characteristics of 3D-printed PLA polymer
Authors: Zhiani Hervan Sahar , Altınkaynak Atakan , Parlar Zeynep
Published: October 2020

The mechanical and tribological behaviors of the parts manufactured with 3D printing methods differ with variations in the manufacturing parameters. This paper aims to investigate the effect of the layer thickness and layer orientation parameters on the hardness, friction coefficient and wear properties of PLA samples printed by Fused Deposition Modelling (FDM) method. Samples were printed with three different layer thicknesses in two different build orientations. The hardness of the samples was tested by D-type shore hardness durometer and a pin-on-disc setup was used to measure the friction coefficient and wear rate of the samples. The analysis of the experimental results showed the distinctive effect of the layer orientation and layer thickness which further discussed in the paper.
Worlds apart or coproduction? Investigating the relationship between knowledge users and producers
Authors: Høydal Øyunn Syrstad
Published: October 2020

Based on interviews and survey data, this article examines the role of civil servants in the process of external evaluations. Traditionally the political–administrative system and the research sector have been seen as worlds apart, their differences hindering the use of evidence in policy, creating a need for knowledge brokering. However, there are perspectives taking the opposite position, recognizing the mutual influence of policy and research in the coproduction of knowledge. This study suggests that both perspectives are relevant and together could provide a better point of departure for understanding the production and use of evidence in policy.
Diagnostic evaluation and Bayesian Updating: Practical solutions to common problems
Authors: Befani Barbara
Published: October 2020

This article discusses several practical issues arising with the application of diagnostic principles to theory-based evaluation (e.g. with Process Tracing and Bayesian Updating). It is structured around three iterative application steps, focusing mostly on the third. While covering different ways evaluators fall victims to confirmation bias and conservatism, the article includes suggestions on which theories can be tested, what kind of empirical material can act as evidence and how to estimate the Bayes formula values/update confidence, including when working with ranges and qualitative confidence descriptors. The article tackles evidence packages (one of the most problematical practical issues), proposing ways to (a) set boundaries of single observations that can be considered independent and handled numerically; (b) handle evidence packages when numerical probability estimates are not available. Some concepts are exemplified using a policy influence process where an institution’s strategy has been influenced by a knowledge product by another organisation.
A telemedicine strategy to reduce waiting lists and time to specialist care: A retrospective cohort study
Authors: Pfeil Juliana N , Rados Dimitris V , Roman Rudi , Katz Natan , Nunes Luciana N , Vigo Álvaro , Harzheim Erno
Published: October 2020

Introduction

The demand for specialty care is rising worldwide. In the state of Rio Grande do Sul, Brazil, more than 150,000 people were waiting for specialist consultations in 2013. A telemedicine programme (RegulaSUS) developed referral protocols, audited waitlisted cases, authorised/prioritised referrals by risk and discuss deferred cases primary-care physician. This study assesses the effectiveness of RegulaSUS.

Methods

A retrospective cohort analysis with contemporaneous controls was performed from June 2014 to June 2016. Six medical specialties included in RegulaSUS (50,185 patients) were compared to 50,124 control patients waitlisted according to the usual routine (scheduled for specialty consultation at the next available date). The groups were matched (1:1) by semester and year of waitlisting and by the specialty demand-to-supply ratio. Primary outcomes were referral-to-consultation time and number of waitlisted patients.

Results

The mean referral-to-consultation time was 584.8 days in the intervention group and 607.0 days in controls ( p<0.001). For specialties regulated by RegulaSUS, the mean referral-to-consultation time was 237.6 days for higher-risk patients. At the end of the observation, 26,708 control patients had been unlisted compared to 31,050 patients in the intervention group (reduction of 53.5% vs. 61.9%, respectively; p<0.001). The number of cancelled referrals was lower in the control group ( n=14,403; 28.7%) than in the intervention group ( n=16,387; 32.7%; p<0.001).

Discussion

Telemedicine support for primary care effectively decreased the time to specialty consultation, reduced the number of waitlisted patients and allowed sicker patients to reach a specialist faster.
Teledentistry: Increasing utilisation of oral-health services for children in rural areas
Authors: Surdu Simona , Langelier Margaret
Published: October 2020

Introduction

The objective of this study was to evaluate factors influencing utilisation of follow-up oral-health services in general dentistry clinics among children subsequent to a teledentistry consultation and treatment with a paediatric dental specialist.

Methods

Conducted in 2017, the study included 144 children living in rural upstate New York who experienced a teledentistry consultation in 2015–2016 at one of several local general dentistry clinics. A remotely located paediatric dental specialist provided consultation services in the teledentistry visit and treatment services in the specialty dental clinic. Associations between follow-up services at the general dentistry clinics and patients’ characteristics, specialty treatment recommendations, case-management services, timeliness of treatments and travel distances were evaluated.

Results

The study results indicated that most children completed a treatment plan (97.2%) at the specialty clinic and subsequently accessed follow-up oral-health services at one of the local general dentistry clinics (77.1%) where teledentistry services were provided. Children’s utilisation of follow-up services in general dentistry clinics was associated with a shorter time to specialty treatment ( p = 0.013) and fewer case-management contacts ( p = 0.004). Children who had a longer time to treatment initiation ( p < 0.001) or completion ( p = 0.043) required significantly more case-management services than other children.

Discussion

The study found that case severity and compliance with treatment were predictors of utilisation of oral-health services in general dentistry clinics. An additional finding was that case-management interventions were important in facilitating specialty dental care.
How adolescents understand their values: A qualitative study
Authors: Lewis-Smith Iona , Pass Laura , Reynolds Shirley
Published: October 2020

An important component of some psychological therapies is the use of clients’ values to motivate behaviour change. Values are understood to be developed during childhood and adolescence but there has been limited exploration of how young people experience values and their function across contexts. This study aimed to explore adolescents’ understanding of the concept of ‘values’ and to elicit their experiences of values. Semi-structured, individual interviews were conducted with 11 adolescents aged 12–17 years. Thematic analysis was used to identify themes. Young people were readily able to discuss the meaning of ‘values’ and their own personal values. Three main themes were identified: (1) what values are (in general, and specific to themselves), (2) where values come from (relationships, education, growing up), and (3) why values are important (prioritising/decision making, reflecting on values is helpful). The adolescents in this study demonstrated an in-depth understanding of the meaning, origins and functions of values. The results suggest young people may welcome and benefit from opportunities to discuss their values, including in therapy.
A randomized controlled trial of cognitive behavioral therapy compared with diabetes education for diabetic peripheral neuropathic pain
Authors: Higgins Diana M , Heapy Alicia A , Buta Eugenia , LaChappelle Kathryn M , Serowik Kristin L , Czlapinski Rebecca , Kerns Robert D
Published: October 2020

A randomized controlled trial compared cognitive behavioral therapy (CBT) and diabetes education (ED) as an adjunctive treatment for diabetic peripheral neuropathic pain (DPNP). We examined change from baseline to 12- and 36-week follow-up in overall pain intensity (NRS), neuropathic pain intensity/quality, pain interference, and mental health functioning, among others. Although CBT participants demonstrated improvement in pain intensity NRS, there were no between-condition differences at either follow-up. CBT reduced neuropathic pain intensity at 12-weeks more than ED. At 36-weeks, CBT was superior to ED for improving pain interference and mental health functioning. Results provide evidence of benefit of CBT for DPNP.

ClinicalTrials.gov Identifier: NCT00830011
Adverse event reporting in intervention research for young autistic children
Authors: Bottema-Beutel Kristen , Crowley Shannon , Sandbank Micheal , Woynaroski Tiffany G
Published: October 2020

Our team examined 150 reports on group-design, non-pharmacological interventions for young autistic children, to determine the prevalence of adverse event reporting. We found that only 11 studies mentioned adverse events; one indicated adverse events occurred, and an additional three indicated adverse effects occurred (i.e. adverse events that could be attributed to the intervention). We also coded reasons for participant withdrawal and found that of the 54 studies that reported reasons for withdrawal, 10 studies reported reasons that could be categorized as adverse events, 8 reported reasons that could be categorized as adverse effects, and an additional 12 studies reported reasons that were too vaguely described to determine adverse event status. We recommend that autism intervention researchers make concerted efforts to monitor, classify, and report adverse events so that practitioners, policy-makers, and families are better equipped to weigh potential benefits of interventions against potential harms.

Lay abstract

In this study, we looked at published research on interventions for young autistic children that did not involve administering medication. We were interested in determining how often studies reported on whether adverse events (i.e. physical or psychological distress to the participants) or adverse effects (i.e. adverse events that are thought to be caused by the intervention) had occurred. We found that of the 150 reports we examined, only 11 mentioned adverse events. One of these studies reported adverse events occurred, and three reported that adverse effects occurred. We also reviewed the studies to examine the reasons that were given to explain why any participants dropped out of the intervention (termed “withdrawal”), to determine if any of these reasons could be considered adverse events or adverse effects. Fifty-four studies described reasons for withdrawal, and 10 of these studies had reasons that could be categorized as an adverse event, 8 studies had reasons that could be categorized as an adverse effect, and an additional 12 studies had reasons that were too vaguely described to determine whether they were adverse events or not. We recommend that autism intervention researchers develop more systematic methods of looking for and reporting adverse events and effects, so that professionals and families can be better informed when choosing to enroll their autistic children in interventions.
Disciplining empathy: Differences in empathy with U.S. medical students by college major
Authors: Olsen Lauren D. , Gebremariam Hana
Published: October 2020

Citing their students’ low levels of empathy, medical educators have scrambled to implement curricula with the hopes of buffering against the corrosive effects of biomedical and clinical experiences in medical school. The assumption undergirding these studies by social scientists and medical educators alike is that immersion in biomedical education and clinical experience erodes students’ empathic capacities, and that exposure to humanities and social sciences content will amend these losses. But we do not know if this assumption is correct. In this project, we empirically assess this assumption by utilizing a unique data set constructed from student applicant and survey data from the American Medical College Application Service (AMCAS) and the Association of American Medical Colleges (AAMC). We test whether medical school students ( N = 8255) from the United States (U.S.) with different academic backgrounds represented by their college major have different levels of empathy, net of demographic control variables. We report two findings. First, we find that students who majored in humanities or interpretive social sciences disciplines have higher empathy scores than their peers who majored in the positivistic social sciences and STEM (science, technology, engineering, and mathematics) disciplines. Second, we find that the relationship between empathy and time in medical school is more nuanced than we would expect from the existing literature.
Numerical study of dynamic responses of reinforced concrete infilled frames subjected to progressive collapse
Authors: Yu Jun , Gan Yi-Ping , Liu Jun
Published: October 2020

Recently, the contribution of infill walls on progressive collapse resistance of reinforced concrete (RC) structures attracts a great many research attentions, but the research interests are mainly concentrated on the static resistance and the macro-modeling approaches, which require predefined one-dimensional load paths through two-dimensional walls. However, the load transfer paths in dynamic loading regime are still not fully understood. To this end, high-fidelity finite element (FE) models of multi-story RC infilled frames are built and validated through quasi-static experimental results. Then the FE models are used to investigate the dynamic responses of infilled frames under different single and double CRS as well as the effect of the number of stories on the load transfer paths of full-height infill walls (FHIW) and infill walls having opening (IWHO). The results indicate that the load paths along the infill walls in static and dynamic loading regimes are similar prior to the peak resistance but different in post-peak resistance for single infilled story frames. Such difference results from the loading distribution pattern, in which the static loading is typically represented by a concentrated load whereas the dynamic loading involves the uniformly distributed load. Moreover, increasing the number of infilled stories with FHIW, trans-story load paths due to composite effect always exist to enhance resistance and such paths are scenario-dependent. In comparison, the load paths for multi-story frames with IWHO are relatively scenario-independent with minor composite effect. Therefore, to generalize the macro-modeling, it is conservative to ignore the trans-story load paths.
Comparisons of design wind pressures on roof-mounted solar arrays between wind tunnel tests and codes and standards
Authors: Wang Jingxue , Yang Qingshan , Hui Yi
Published: October 2020

The current codes and standards concerning wind loads on roof-mounted solar panels are discussed and summarized. Wind pressures on flat- and slope-roof-mounted solar arrays obtained from wind tunnel tests are compared with the recommended design values in ASCE 7-16 and JIS C 8955: 2017. Different parameters, including building side ratio, aspect ratio and parapet height, are examined. Results show that the largest wind pressures on flat-roof-mounted solar panels of all zones in ASCE 7-16 tend to be 10% to 26% smaller than the experimental results when normalized tributary area An is larger than 103. Uplift wind forces on flat-roof-mounted solar panels in downstream regions obtained from experiments can be larger than the recommended values in JIS C 8955: 2017 for adverse wind, but downward force coefficients are basically smaller than those in JIS C 8955: 2017 for fair wind. 40% to 60% increase on the pressure equalization factor for slope-roof-mounted solar panels is suggested for the potential refinement of ASCE 7-16 based on this study. Meanwhile, proposed pressures of slope-roof-mounted solar panels in JIS C 8955: 2017 might be too conservative according of experimental results.
The impact of mechanical ventilation operation strategies on indoor CO2 concentration and air exchange rates in residential buildings
Authors: Pereira Pedro F. , Ramos Nuno M. M.
Published: October 2020

In Portugal, residential buildings commonly have their ventilation strategy changed after commissioning. This occurs due to the building managers' willingness to reduce shared costs with the electricity needed for fan operation. However, this option is not technically supported, and the effects of such a strategy on indoor air quality-related to human pollutants are yet to be quantified. CO2 was monitored in 15 bedrooms and air exchange rates were calculated for each room. The air exchange rate values ranged from 0.18 to 0.53 h−1 when mechanical extraction ventilation was off, and from 0.45 to 0.90 h−1 when mechanical extraction ventilation was on, which represents an average increase of 119%. With the current intermittent ventilation strategy, all rooms remain above 1500 ppm for a given percentage of time, and 12 rooms presenting CO2 concentrations above 2000 ppm. Simulations of theoretical CO2 concentrations, for a non-interrupted mechanical ventilation strategy show that no rooms would accumulate CO2 concentrations above 2000 ppm, and only 25% would present CO2 concentrations above 1500 ppm. Pearson correlations between the monitored CO2 and human and spatial factors identified two relevant parameters. Those parameters correspond to ratios between CO2 generation and floor area ([Formula: see text]), and airflow with CO2 generation ([Formula: see text]). The proposed ratios could be used as ways to optimise ventilation costs and indoor air quality.
Metaphors in moderation
Authors: Seering Joseph , Kaufman Geoff , Chancellor Stevie
Published: October 2020

Volunteer content moderators are essential to the social media ecosystem through the roles they play in managing and supporting online social spaces. Recent work has described moderation primarily as a functional process of actions that moderators take, such as making rules, removing content, and banning users. However, the nuanced ways in which volunteer moderators envision their roles within their communities remain understudied. Informed by insights gained from 79 interviews with volunteer moderators from three platforms, we present a conceptual map of the territory of social roles in volunteer moderation, which identifies five categories with 22 metaphorical variants that reveal moderators’ implicit values and the heuristics that help them make decisions. These metaphors more clearly enunciate the roles volunteer moderators play in the broader social media content moderation apparatus and can drive purposeful engagement with volunteer moderators to better support the ways they guide and shape their communities.
Being watched and being seen: Negotiating visibility in the NYC ride-hail circuit
Authors: Mosseri Sarah
Published: October 2020

App-based, ride-hail drivers are a highly visible workforce, yet previous research has generally understood their visibility primarily in terms of surveillance. Using data from an ethnographic study of the New York City (NYC) ride-hail circuit, this article explores how drivers experience and negotiate their visibility. Findings reveal that constant monitoring on ride-hail apps feels oppressive to drivers, and it requires them to engage in significant unpaid labor in the form of reputation auditing. Nevertheless, drivers also find ways to “caption” surveillance outputs and thus shape their meanings. They engage in three strategies—juxtaposing existing metrics, expanding the field of vision, and requiring others to bear witness—to clarify, contextualize, and reclaim their visibility. The ability to reconfigure meanings of visibility, and specifically to navigate between the experience of being watched and that of being seen, represents an underexplored avenue of agency within studies of work surveillance.
Returning to the digital world: Digital technology use and privacy management of women transitioning from incarceration
Authors: Seo Hyunjin , Britton Hannah , Ramaswamy Megha , Altschwager Darcey , Blomberg Mathew , Aromona Shola , Schuster Bernard , Booton Ellie , Ault Marilyn , Wickliffe Joi
Published: October 2020

Based on interviews with 75 women transitioning from incarceration, our research identifies technology access and skills barriers facing this population and their underlying concerns and motivations in navigating privacy online. Our results suggest precarious housing and financial situations, concerns about ex-partners, mental health issues, and lack of self-efficacy pose challenges for their access to and use of digital technologies and influence their online privacy perspectives. Many participants reported relying primarily on cellphones for various tasks including job applications. Closing public places including libraries amid the COVID-19 pandemic put them at an even greater disadvantage, as many of them depend on computers or Wi-Fi available in those places. Nothing-to-lose attitudes were salient among this group resulting in many not taking precautionary measures online or choosing to go offline. Our research highlights the importance of building academic-community partnerships to provide technology and privacy education tailored for this population’s particular needs and desires.
Outlining play and playful learning in Finland and Brazil: A content analysis of early childhood education policy documents
Authors: Kangas Jonna , Harju-Luukkainen Heidi , Brotherus Annu , Gearon Liam Francis , Kuusisto Arniika
Published: October 2020

Early childhood education and care is a current interest in many countries. Many international studies have highlighted the importance of high-quality early education environments where learning and play are integrated. Studies show that these types of learning environments have a positive impact on children’s future prospects and overall development. Critical curriculum steering documents from Finland and Brazil form the basis of this study and can similarly be shown to define the quality of these environments, as well as providing definitions of playful learning in these differing cultural contexts. A content analysis explores patterns of the cultural and pedagogical difference of definition. This descriptive comparison permitted similarities and differences between the countries with regard to play to emerge. In this article, the authors explore what these different cultural and pedagogical definitions of play and playful learning are and what they might mean. The article thus makes a methodological contribution to a broader discussion of comparative studies of national curricula in early childhood education with specific regard to children’s engagement, learning and development in and through play. The theoretical conclusions are, however, more tentative, but the authors suggest some innovative ways to conceptualise cultural and pedagogical differences in play by making an analogy with Wittgenstein’s analysis of games in his Philosophical Investigations.
From goods-dominant logic to service-dominant logic? Service, service capitalism and service socialism
Authors: Tadajewski Mark , Jones D. G. Brian
Published: October 2020

Vargo and Lusch (V&L) have claimed that there was a movement from a goods-dominant logic to service-dominant logic in marketing. We problematise this narrative via attention to multiple strands of service discourse from the late 19th to mid-20th century. Our focus begins with the promotion of service in the economics literature. A close reading of a publication important to V&L’s account reveals the politics associated with the rise of service discourse. This is elided in their work. Our genealogy subsequently engages with the publications of A. F. Sheldon. His views are unpacked and links to the Rotary Club explicated. The evidence indicates that service discourse was relational in orientation and ethically driven, with the intertwined themes in Sheldon and Rotary’s publications generalised into an emergent ‘theory of society’ that had applicability around the world. We term this discursive formation ‘service capitalism’. This perspective was contested by a ‘counter manoeuvre’ labelled ‘service socialism’. Service socialism differed fundamentally from Sheldon’s axiology, Rotary’s service capitalism or the midpoint view detailed by Edward Filene due to its focus on the deleterious impact of the profit motive, the significance of ‘use value’, the reorientation from ownership to access-based consumption and attention to human welfare and economic security. Service socialism, we conclude, generates insights that require engagement today.
A comparison of machine learning algorithms for assessment of delamination in fiber-reinforced polymer composite beams
Authors: He Mengyue , Wang Yishou , Ram Ramakrishnan Karthik , Zhang Zhifang
Published: October 2020

Structural health monitoring techniques based on vibration parameters have been used to assess the internal delamination damage of fiber-reinforced polymer composites. Recently, machine learning algorithms have been adopted to solve the inverse problem of predicting delamination parameters of the delamination from natural frequency shifts. In this article, a delamination detection methodology is proposed based on the changes in multiple modes of frequencies to assess the interface, location, and size of delamination in fiber-reinforced polymer composites. Three types of machine learning algorithms including back propagation neural network, extreme learning machine, and support vector machine algorithm were adopted as inverse algorithms for assessment of the delamination parameters, with a special focus on the interface prediction. A theoretical model of fiber-reinforced polymer beam with delamination under vibration was constructed to learn how the frequencies are affected by the delaminations (“forward problem”) and to generate a database of “frequency shifts versus delamination parameters” to be used in machine learning algorithms for delamination prediction (“inverse problem”). Multiple carbon/epoxy fiber-reinforced polymer beam specimens were manufactured and measured by a laser scanning Doppler vibrometer to extract the modal frequencies. Numerical and experimental verification results have shown that support vector machine has the best prediction performance among the three machine learning algorithms, with high prediction accuracy and only requiring a small number of samples. For predicting the interface of delamination which is a discrete variable, support vector machine classification has observed better prediction accuracy and requiring less running time than regression. This study is one of the first to prove the applicability of support vector machine for structural health monitoring of delamination damage in fiber-reinforced polymer composites and has the potential to improve the prediction capability of machine learning algorithms. Another significant outcome of the study is that the interface of delamination has been predicted accurately with support vector machine.
Using the future to transform the design logic of schooling: Consensus statements from an expert panel
Authors: McGrath Jason , Fischetti John
Published: October 2020

We propose a framework of 29 Future School Elements that can be used to consider future models of schooling which we have organised across three pillars of pedagogy, policy and structure. We seek to position the framework within a futures approach to policy making that allows for greater diversity by providing a design logic that can be contextualised, is more pluralistic and can be shaped by a greater number of voices. The findings from our modified Delphi study involved an expert panel who examined the counterfactual research question ‘What if compulsory schooling was a 21st-century invention?’ Consensus statements were formed by the expert panel by rating items based on impact and equity. We explore ways in which utilising a foresight approach can provide a means to reshape future models of schooling in a meaningful and contemporary way that takes account of some of the challenges and forces that have prevented change.
Access to Care as a Barrier to Mammography for Black Women
Authors: Aleshire Mollie E. , Adegboyega Adebola , Escontrías Omar A. , Edward Jean , Hatcher Jennifer
Published: October 2020

Racial disparities in breast cancer screening, morbidity, and mortality persist for Black women. This study examines Black women’s mammography beliefs and experiences with specific focus on barriers to mammography access in an urban city in the South East, United States. This retrospective, qualitative study used Penchansky and Thomas’ conceptualization of health care access as the framework for the data analysis. In-depth, semistructured interviews were conducted with 39 Black women. Structural and personal factors continue to create barriers to mammography among Black women. Barriers to mammography were identified for each of the Penchansky and Thomas five dimensions of access to care: accessibility, affordability, availability, accommodation, and acceptability. Clinical practice strategies to increase mammography screening in Black women must be multifactorial, patient-centered, and culturally congruent. Policy development must address the structural barriers to mammography screening through expansion of health insurance coverage and increased accessibility to health care.
Influence of orthopedic support structure and construction on compression and behavior during stress relaxation
Authors: Mikucioniene D , Muraliene L
Published: October 2020

This work was focused on changes of the compression generated by knitted orthopedic supports during the stress relaxation in order to find in which period of the stress relaxation the most significant part of the compression is lost. The influence of knitted structure, elastomeric inlay-yarn insertion density and shape/orientation of the rigid element fixed on the fabric on the compression and its changes under the stress relaxation was also investigated in this study. 11 different knitted structures and constructions were used in this research. It was found that the higher density of elastomeric inlay-yarn insertion into the knitted structure is not only responsible for higher compression generation, but also makes compression degradation during the time slower. In addition, the higher pre-tension of the elastomeric inlay-yarn leads to the faster relaxation process. Moreover, the shape and orientation of the rigid element can significantly affect the compression generation, however behavior of all variants during the stress relaxation is very similar. Evaluation of the tensile force after at least 120-300 s of the stress relaxation has to be used in design algorithm of very different compression products and applied in estimation of the compression at different manufacturing stages of the product.
Radiotherapy Dose and Induction Chemotherapy Cycles Are Associated With Prognosis and Toxicity Risk: A Retrospective Study of 227 Patients With Unresectable Stage III Non-Small-Cell Lung Cancer
Authors: Chen Liyao , Hou Yu , Xia Yaoxiong , Chang Li , Diao Xianmin , Wang Li , Li Lan , Long Qing , Liu Ying , Liu Yan , Li Wenhui
Published: October 2020

Objective:

Concurrent chemoradiation (cCHRT) has been confirmed as the standard treatment for local advanced non-small-cell lung cancer (NSCLC). This study is to assess the appropriate timing of radiotherapy and cycles of induction chemotherapy for those patients.

Methods:

227 inoperable stage III NSCLC patients were selected, we analyzed the potential prognostic factors and the influence of induction chemotherapy was evaluated.

Results:

The median survival time was 20.7 months; only 25 patients chose chemotherapy alone (11.0%), 137 patients underwent sequential chemoradiation (sCHRT, 60.4%), and 65 patients received cCHRT (28.6%). Multivariate analyses showed radiation therapy (P = 0.001), the Eastern Cooperative Oncology Group (ECOG) score (P = 0.000) and the lymph node stage (P = 0.001) were independent prognostic factors. cCHRT was not found to be superior (P = 0.330). We selected patients received 60-66 Gy and found the cCHRT groups achieved a relatively better outcome, with a median Overall Survival (OS) of 25.2 months vs 20.1 months in the sCHRT group (P = 0.019). We also found cycles of induction chemotherapy did not compromise survival; however, ≥3 cycles resulted in more grade 3-4 hematology toxicities, with a proportion of 18/99 compared with 53/103 among patients who underwent ≤3 cycles. In addition, higher grade hematology toxicities and poor ECOG were also the most common reasons for abandoning cCHRT.

Conclusions:

For inoperable stage III NSCLC, cCHRT showed its superiority only when the radiotherapy dose was 60-66 Gy. Cycles of induction chemotherapy did not interfere with survival; however, ≥3 cycles resulted in more grade 3-4 hematology toxicities, leading to the cessation of cCHRT.
Oncogenic Long Noncoding RNA DARS-AS1 in Childhood Acute Myeloid Leukemia by Binding to microRNA-425
Authors: Dou Binghua , Jiang Zhu , Chen Xiaoguang , Wang Chunmei , Wu Jing , An Jindou , Sheng Guangyao
Published: October 2020

Objective:

Acute myeloid leukemia (AML) represents a hematological cancer. The aim of the investigation was to probe the regulatory relevance of long non-coding RNA (lncRNA) aspartyl-tRNA synthetase anti-sense 1 (DARS-AS1)/microRNA-425 (miR-425)/transforming growth factor-beta 1 (TGFB1) to the development of AML.

Methods:

The DARS-AS1 expression in bone marrow tissues was first analyzed in healthy subjects and AML patients. Subsequently, AML cell lines with DARS-AS1 knockdown were constructed, followed by cell proliferation and apoptosis assays. Afterward, downstream miRNA of DARS-AS1 and target mRNA of the miRNA were analyzed by bioinformatics, and their binding relationships were verified. Functional rescue experiments were then implemented. Finally, activation of the Smad2/3 signaling in MV4-11 and BF-24 cells were detected by western blot.

Results:

DARS-AS1 was overexpressed in bone marrow tissues of AML patients and cells, and DARS-AS1 knockdown suppressed the proliferation of AML cells and induced apoptosis. DARS-AS1 bound to and negatively correlated with miR-425. Further results suggested that TGFB1 might be a target gene of miR-425 and could promote Smad2/3 phosphorylation and nuclear translocation. Finally, DARS-AS1 depletion could diminish the tumor volume in vivo.

Conclusion:

All in all, we highlighted here that DARS-AS1 enhanced the expression of TGFB1 through binding to miR-425 to modulate AML progression via the Smad2/3 pathway, which might perform as a therapeutic target for AML.
COVID-19 Wounds: Unusual Lower Extremity Bullae
Authors: Zinder Roman , Andrews Carolyn , Cristallo Jessica , Flattau Anna
Published: October 2020

As the COVID-19 pandemic emerged, skin manifestations have been reported as part of this disease’s multisystem manifestations. While a rash similar to chilblains in acral distribution has been the most commonly reported complication, we noted a pattern of more severe lower extremity skin complications, specifically large bullae, in a series of COVID-19 patients.
The Effect of Mindfulness-Based Stress Reduction Group Counseling on Psychological and Inflammatory Responses of the Women With Breast Cancer
Authors: Mirmahmoodi Motahareh , Mangalian Parvin , Ahmadi Atefeh , Dehghan Mahlagha
Published: October 2020

Introduction: Breast cancer is common among women and reduces their quality of life. The current study aimed to investigate the effectiveness of mindfulness-based stress reduction group counseling in alleviating psychological responses such as anxiety, depression, stress, and regulating laboratory tests including cortisol and C-reactive protein (CRP) in women with breast cancer. Methods: This randomized clinical trial was conducted based on convenience sampling. Participants were divided into 2 groups (control and intervention groups) with block randomization. The intervention group received mindfulness-based stress reduction group counseling during 8 weeks. The participants completed the Beck anxiety inventory, Beck-II depression inventory, and perceived stress scale before and after the intervention and their blood samples were taken to check their cortisol and CRP. Results: After the intervention, the MBSR group had significantly lower anxiety compared with the control group ( P < .001). No significant difference was found between the 2 groups in the reduction of perceived stress and depression ( P < .05). In addition, no significant difference was found between the 2 groups in CRP and cortisol levels after the intervention ( P > .05). Conclusion: The present study showed the effectiveness of mindfulness-based cognitive therapy in improving anxiety rather than the stress, depression, and inflammatory laboratory factors such as cortisol and CRP in women with breast cancer. Therefore, the psychological symptoms of these patients can be improved at different stages of treatment by providing this type of training.
The Effect of Yoga Interventions on Cancer-Related Fatigue and Quality of Life for Women with Breast Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: O’Neill Meagan , Samaroo Dominic , Lopez Christian , Tomlinson George , Santa Mina Daniel , Sabiston Catherine , Culos-Reed Nicole , Alibhai Shabbir M. H.
Published: October 2020

Background:

Women with breast cancer (BC) are living longer with debilitating side effects such as cancer-related fatigue (CRF) that affect overall well-being. Yoga promotes health, well-being and may be beneficial in reducing CRF. Although there have been previous systematic reviews and meta-analyses, the effects of yoga on CRF and quality of life (QOL) remain unclear, particularly in comparison with other types of physical activity (PA). Our objective is to carry out a systematic review and meta-analysis of the effects of yoga on CRF and QOL in women with BC.

Methods:

Electronic databases were searched (MEDLINE, Embase Classic+Embase and EMB Reviews, Cochrane Central CT) from inception to May 2018. Randomized controlled trials were included if they were full text, in English, included a yoga intervention, a comparator (including non-PA usual care or alternate PA intervention), and reported on CRF or QOL. Effects of yoga were pooled using standardized mean difference (SMD) via a random effects model.

Results:

Of the 2468 records retrieved, 24 trials were included; 18 studies compared yoga to a non-PA comparator and 6 to a PA comparator. Yoga demonstrated statistically significant improvements in CRF over non-PA (SMD −0.30 [−0.51; −0.08]) but not PA (SMD −0.17 [−0.50; 0.17]) comparators. Additionally, yoga demonstrated statistically significant improvements in QOL over non-PA (SMD −0.27 [−0.46; −0.07]) but not PA (SMD 0.04 [−0.22; +0.31]) comparators.

Discussion:

This meta-analysis found that yoga provides small to medium improvements in CRF and QOL compared to non-PA, but not in comparison to other PA interventions.
Alterations of Resting EEG in Hallucinating and Nonhallucinating Schizophrenia Patients
Authors: Arora Madhav , Knott Verner J. , Labelle Alain , Fisher Derek J.
Published: October 2020

Auditory hallucinations (AHs) are a common symptom of schizophrenia and contribute significantly to disease burden. Research on schizophrenia and AHs is limited and fails to adequately address the effect of AHs on resting EEG in patients with schizophrenia. This study assessed changes in frequency bands (delta, theta, alpha, beta) of resting EEG taken from hallucinating patients (n = 12), nonhallucinating patients (n = 11), and healthy controls (n = 12). Delta and theta activity were unaffected by AHs but differed between patients with schizophrenia and healthy controls. Alpha activity was affected by AHs: nonhallucinators had more alpha activity than hallucinators and healthy controls. Additionally, beta activity was inversely related to trait measures of AHs. These findings contribute to the literature of resting eyes closed EEG recordings of schizophrenia and AHs, and indicate the role of delta, theta, alpha, and beta as markers for schizophrenia and auditory hallucinations.