bluuebunny/crossref_metadata_2025 huggingface dataset:
Validation of the Inventory of Callous-Unemotional Traits Among a Portuguese Sample of Detained Juvenile Offenders
Authors: Pechorro Pedro , Ray James V. , Barroso Ricardo , Maroco João , Gonçalves Rui Abrunhosa
Published: October 2014

The main aim of the present study was to examine the psychometric properties of the Inventory of Callous-Unemotional Traits (ICU) among a sample of incarcerated male Portuguese juvenile offenders ( N = 221). Based on this sample, the Portuguese version of the ICU demonstrated promising psychometric properties, namely, in terms of factor structure, internal consistency, convergent validity, discriminant validity, and concurrent validity that generally justifies its use among this population. Statistically significant associations were found with conduct disorder, age of criminal onset, crime seriousness, physical violence use in committing crimes, alcohol use, cannabis use, and cocaine/heroin use.
Reflective practice in the library and information sector
Authors: Greenall Judith , Sen Barbara Anne
Published: October 2014

This study explores the use of reflection by library and information staff to support practice and continuing development. A questionnaire was sent to library and information mailing lists. A total of 424 responses were received, though the response rate varied for each question. Of 423 respondents 92% identified themselves as reflective practitioners, and 52% of 363 respondents engaged in reflective writing. A number of benefits and barriers were identified. It is concluded that reflective practice and reflective writing are valuable tools for library and information staff, particularly for professional development. Employers and professional bodies have a role in facilitating reflective practice.
Cholecystic adenocarcinoma and pancreatic insulinomas in a goat
Authors: Yau Wilson , Rissi Daniel R.
Published: October 2014

A 13-year-old female Boer goat with a history of chronic arthritis and recurrent episodes of recumbency, increased serum gamma-glutamyl transferase, and complete inability to stand was submitted for necropsy. Gross changes included the presence of a white, firm, smooth, 6 cm × 4 cm × 3 cm mass that diffusely expanded and partially effaced the gall bladder and infiltrated the adjacent hepatic parenchyma. On cut surface, the mass was pale yellow and had small, irregular, dark yellow areas. Scattered through the pancreas were 2 gray, well-demarcated, soft, homogeneous, 1 cm in diameter nodules that bulged out from the capsular surface. The right femoral head had a locally extensive area of cartilage erosion. Histological and immunohistochemical evaluation of the gall bladder and pancreatic nodules revealed a primary cholecystic adenocarcinoma and multifocal insulinomas, respectively. A metastatic focus from the gall bladder neoplasm was observed infiltrating the right adrenal gland medulla. The goat also had mild pulmonary infestation by Muellerius capillaris. Primary hepatobiliary and pancreatic neoplasia is rare in goats, and to the authors’ knowledge, neither cholecystic adenocarcinoma nor pancreatic insulinomas have been previously reported in this species.
Retrospective study of central nervous system lesions and association with Parelaphostrongylus species by histology and specific nested polymerase chain reaction in domestic camelids and wild ungulates
Authors: Dobey Carrie L. , Grunenwald Caroline , Newman Shelley J. , Muller Lisa , Gerhold Richard W.
Published: October 2014

Formalin-fixed, paraffin-embedded tissues from elk ( Cervus elaphus), goats, and camelids with case histories and lesions suggestive of Parelaphostrongylus tenuis were examined by histology to characterize lesions that could aid in definitively diagnosing P. tenuis infection. Additionally, sections of paraffin-embedded tissue were used in a nested polymerase chain reaction (nPCR) using Parelaphostrongylus-specific primers to determine how PCR results corresponded with histological findings. Histological changes in brain and spinal cord consisted of linear tracks of hemorrhage; tracks or perivascular accumulations of hemosiderin-laden macrophages; acute foci of axonal degeneration and/or linear glial scars; and perivascular, parenchymal, or meningeal accumulations of eosinophils and/or lymphocytes and plasma cells. Of the 43 samples with histologic lesions consistent with neural larval migrans, 19 were PCR positive; however, only 8 were confirmed Parelaphostrongylus by DNA sequencing. Additionally, 1 goat was identified with a protostrongylid that had a 97% identity to both Parelaphostrongylus odocoilei and a protostrongylid nematode from pampas deer ( Ozotoceros bezoarticus celer) from Argentina. None of the histologic lesions individually or in combination correlated statistically to positive molecular tests for the nematode. The results indicate that it is possible to extract Parelaphostrongylus DNA from formalin-fixed, paraffin-embedded tissue, but extended fixation presumably can cause DNA crosslinking. Nested PCR provides another diagnostic tool to identify the cause of neurologic disease in camelids and elk with histologic lesions consistent with neural larval migrans. Furthermore, potential novel protostrongylid DNA was detected from a goat with lesions consistent with P. tenuis infection, suggesting that other neurotropic Parelaphostrongylus species may occur locally.
Health Care Employee Perceptions of Patient-Centered Care
Authors: Balbale Salva Najib , Turcios Stephanie , LaVela Sherri L.
Published: October 2014

Given the importance of health care employees in the delivery of patient-centered care, understanding their unique perspectives is essential for quality improvement. The purpose of this study was to use photovoice to evaluate perceptions and experiences around patient-centered care among U.S. Veterans Affairs (VA) health care employees. We asked participants to take photographs of salient features in their environment related to patient-centered care. We used the photographs to facilitate dialogue during follow-up interviews. Twelve VA health care employees across two VA sites participated in the project. Although most participants felt satisfied with their work environment and experiences at the VA, they identified several areas for improvement. These included a need for more employee health and wellness initiatives and a need for enhanced opportunities for training and professional growth. Application of photovoice enabled us to learn about employees’ unique perspectives around patient-centered care while engaging them in an evaluation of care delivery.
Socio-Translational Collaboration in Qualitative Inquiry
Authors: Littig Beate , Pöchhacker Franz
Published: October 2014

In the face of long-standing neglect for issues of multilingualism in qualitative inquiry, this article proposes a novel collaborative approach to coping with translation issues in interviewing. Building on recent efforts at developing a better understanding of linguistic challenges to research methodology, the authors call for the systematic involvement of qualified interpreters and translators throughout the process of qualitative inquiry, and describe their role in all relevant stages of a research project, using expert interviews as a case in point. It is argued that such socio-translational collaboration can help ensure that social scientists engaging in qualitative inquiry will be “less lost in translation.”
Patient communication self-efficacy, self-reported illness symptoms, physician communication style and mental health and illness in hospital outpatients
Authors: Capone Vincenza
Published: October 2014

In this cross-sectional study, we investigated the associations between patient communication self-efficacy and self-reported symptoms in doctor–patient communication, as perceived by patients, and the mental health and illness of hospital outpatients. Using data from a sample of 74 outpatients ( mean age = 37.58 years, standard deviation = 12.54), a structural equation model was calculated. The results showed that communication self-efficacy and respectful behaviour were associated with mental health and illness. Furthermore, self-reported symptoms were correlated with mental illness. Gender and educational differences also occurred. The findings suggest that enhancing patients’ communication skills could benefit outpatients in general, but female and less educated patients in particular.
Review of Continuing Education and Published Literature Related to Women’s Health and Pharmacy
Authors: Moreau Cynthia , Wilson Debbie L.
Published: October 2014

Background: In 2004, the American Association of Colleges of Pharmacy and collaborating organizations created a framework for women’s health instruction as a guide for integrating women’s health into pharmacy curricula. This article expands on the findings of that project by identifying educational opportunities with a women’s health focus that are available for pharmacists. Objective: To review educational opportunities available to pharmacists related to women’s health and to review the pharmacist’s role in women’s health in the published literature. Methods: The continuing education requirements for each of the 50 states and the District of Columbia were reviewed, and a search of continuing education programs for pharmacists on women’s health was conducted. A review of published literature about pharmacy and women’s health was conducted. Results: One state had a continuing education requirement related to emergency contraception, and 62 continuing education programs were found to have a focus on women’s health. The literature review returned 331 articles describing the role of pharmacy in women’s health, of which 55 were included. Conclusions: Pharmacists across different practice settings have a role in women’s health care. There is much emphasis placed on the pharmacist’s role in relation to contraception but increased education in other topics is also important. National pharmaceutical organizations can promote women’s health education for pharmacists.
Growth hormone receptor signaling is dispensable for HSC function and aging
Authors: Stewart Morag H. , Gutierrez-Martinez Paula , Beerman Isabel , Garrison Brian , Gallagher Emily J. , LeRoith Derek , Rossi Derrick J.
Published: October 2014

Key Points

Ghr is specifically expressed on HSCs within the hematopoietic system and is dynamically regulated upon HSC aging and activation. Ghr is dispensable for HSC function.
Superimposed algorithms for the split equilibrium problems and fixed point problems
Authors: Zhu Li-Jun , Yao Zhangsong , Liou Yeong-Cheng , Yao Yonghong
Published: October 2014

The split common problems for finding the equilibrium points and fixed points have been studied. A parallel superimposed algorithm is introduced to solve this split common problem. Strong convergence theorems are shown with some analysis techniques.

MSC:49J30, 47H09, 65K10.
Risk of contralateral second primary breast cancer according to hormone receptor status in Germany
Authors: Rusner Carsten , Wolf Katharina , Bandemer-Greulich Ulrike , Engel Jutta , Stegmaier Christa , Holleczek Bernd , Schubert-Fritschle Gabriele , Tillack Anett , Stang Andreas
Published: October 2014

Introduction

Hormone receptor (HR) status has become an established target in treatment strategies of breast cancer. Population-based estimates of contralateral breast cancer (CBC) incidence by HR subtype in particular are limited. The aim of this study was to provide detailed data on CBC incidence for Germany.

Methods

Invasive breast cancer data were extracted on 49,804 women yielding 594 second primaries from the cancer registries of the Federal States of Brandenburg and Saarland and the area of Munich for the period from 1998 to 2007. Multiple imputation was used on missing values for HR status. We estimated standardized incidence ratios (SIRs) with 95% confidence intervals (95%CIs).

Results

SIR estimates of CBC among women diagnosed with an invasive first primary breast cancer (FBC) of any HR subtype ranged from 1.0 to 1.5 in the three registries. Pooling three registries’ data, the SIR of HR-positive CBC was 0.7 (95%CI: 0.6 to 0.8) among women with HR-positive FBC. For those women with HR-negative FBC, the SIR of HR-negative CBC was 8.9 (95%CI: 7.1 to 11.1). Among women with FBC diagnosed before the age of 50 years, incidence of CBC was increased, especially for HR-negative FBC (SIR: 9.2; 95%CI: 7.1 to 11.9).

Conclusions

HR status of the first primary and age at first diagnosis is relevant for predicting risk of CBC. Particularly, patients with HR-negative FBC had elevated risks.
Benchmarking biofuels—a comparison of technical, economic and environmental indicators
Authors: Müller-Langer Franziska , Majer Stefan , O'Keeffe Sinéad
Published: October 2014

The global demand for energy, particularly for transport fuels, will continue to increase significantly in the future. In addition to other options, like increased technological efficiencies, traffic reduction or modal shift, biofuels are promoted to contribute strongly to the transport sector in the years to come. Biofuels are also promoted as part of the EU strategy for decarbonising the transport sector with the aim of reducing associated GHG emissions. This paper considers some of the most important biofuels. A selection of biofuel options (biodiesel, bioethanol, biomethane, hydrotreated vegetable oils and fats, lignocellulosic-based fuels) were characterised by their conversion technologies and stage of development. They were analysed, concerning technical (overall efficiency), economic (investments and biofuel production costs) and environmental aspects (GHG performance). Additionally, GHG mitigation costs were calculated with regard to the GHG-based biofuel quota.
Robustness of Partial Least-Squares Models to Change in Sample Temperature: I. A Comparison of Methods for Sucrose in Aqueous Solution
Authors: Acharya Umesh K. , Walsh Kerry B. , Subedi Phul P.
Published: October 2014

Sample temperature is well known to impact model performance for prediction of chemical attributes in high-moisture-content samples when using short-wave near infrared spectroscopy. A number of methods proposed to reduce this effect were compared in this study. A short-wave near infrared spectroscopy system operating in transflectance geometry was used to record spectra of sucrose solutions (mean = 4.16% and SD = 5.8% w/v) at different temperatures. Partial least-squares regression models were developed using spectra of sucrose solutions collected at 15°C and tested on spectra of an independent set of sucrose solutions at a sample temperature of 35°C. As sample temperature impacts the water peak, the performance of a model of sucrose content is perturbed, mainly through an increase in bias. Addition of a relatively small number of spectra of the same set of samples at different temperatures facilitated a model robust to temperature, but continued addition of samples at 15°C beyond the ratio of 1:125 overwhelmed the compensation effect, resulting in a model that was not robust to temperature. The use of orthogonal scatter correction (OSC), generalised least square weighting (GLSW), external parameter orthogonalisation (EPO) and repeatability file were considered. Of these methods, OSC corrected bias but impacted bias corrected root mean square error of prediction ( SEP) and r2, EPO performed better but still with some bias, GLSW gave the best r2 and SEP result but still with bias, while use of the repeatability file method gave the best overall result.
Near Infrared Hyperspectral Image Regression: On the Use of Prediction Maps as a Tool for Detecting Model Overfitting
Authors: Gowen Aoife , Burger James , Esquerre Carlos , Downey Gerry , O'Donnell Colm
Published: October 2014

Calibration models developed from hyperspectral imaging data may be applied at the pixel level to generate prediction maps that estimate the spatial distribution of components in a sample. Such prediction maps facilitate direct visual interpretation of model performance, and performance indicators can be extracted from them. These maps can be used as a tool to evaluate calibration models developed on hyperspectral imaging data. This paper presents a method for calibration model evaluation based on information obtained from prediction maps and demonstrates its usefulness for preventing overfitting. Partial least-squares regression was used for model calibration in this study, although in principle the proposed method may be used to evaluate other multivariate calibration methods, e.g. ridge regression and principal-components regression.
Near Infrared Spectroscopy Detection of Copper in Pig Manure and the Spectral Basis of the Analysis
Authors: Shen Xiuli , Yang Zengling , Huang Guangqun , Han Lujia
Published: October 2014

Conventional methods based on wet chemical analysis for investigating heavy metals in animal manure are relatively expensive and time-consuming. This study investigated the use of near infrared (NIR) spectroscopy to detect copper (Cu) in animal manure and then identified the spectral basis of the calibration. A total of 118 pig manure samples were collected from four provinces in China. Spectra were acquired in the range of 10,000 to 4000 cm−1 using a Fourier-transform near infrared spectrometry system. Results showed that the prediction of Cu concentration in pig manure by NIR spectroscopy is feasible ( r2 = 0.84, root mean square error of prediction= 198 mg kg−1, ratio of standard error to standard deviation = 2.4). Cu in pig manure can be detected by NIR spectroscopy because a high percentage of the Cu is complexed with CONH2 or CONHR functional groups of organic ligands such as protein, urea, amino acids and other amide compounds.
Review: Formulae for Absorption Spectroscopy Related to Idealised Cases
Authors: Dahm Donald J. , Dahm Kevin D.
Published: October 2014

Over the years, a wide variety of formulae have been developed to describe absorption and scatter of light from particles with idealised characteristics. Many of these have been found to be very useful in spectroscopy. The solutions that are mathematically exact are generally limited to light that is travelling in one direction (as in the Bouguer–Lambert law) or two directions (as in the Kubelka–Munk equation). Many of the equations are well known in a form quite different from that presented by those who developed them. The most successful of these mathematical treatments have tended to be presented in terms of absorption by, and scatter from, layers of material. In order to be applicable to real samples, the layer should be representative of the sample. These formulae allow one to predict or model the remission, transmission and/or absorption for a sample, given scattering and absorption coefficients that accurately represent the sample. The inverse problem—using spectral data to calculate absorption coefficients that accurately represent the material of which the sample is composed—is conceptually more complex for scattering samples, owing to the fact that the processes of absorption and scattering influence each other. To the extent that real samples can be represented as a series of plane parallel layers well separated by layers of air, a solution to this “inverse problem” has been realised for scattering samples, analogous to the use of Beer's law for clear solutions. This review summarises the relevant theory in a way that assumptions and limitations can be clearly understood, and misconceptions can be avoided.
Mandatory versus Discretionary Spending: The Status Quo Effect
Authors: Bowen T. Renee , Chen Ying , Eraslan Hülya
Published: October 2014

Do mandatory spending programs such as Medicare improve efficiency? We analyze a model with two parties allocating a fixed budget to a public good and private transfers each period over an infinite horizon. We compare two institutions that differ in whether public good spending is discretionary or mandatory. We model mandatory spending as an endogenous status quo since it is enacted by law and remains in effect until changed. Mandatory programs result in higher public good spending; furthermore, they ex ante Pareto dominate discretionary programs when parties are patient, persistence of power is low, and polarization is low. (JEL C78, E62, H41, H61)
Efficiency, Equality, and Labeling: An Experimental Investigation of Focal Points in Explicit Bargaining
Authors: Isoni Andrea , Poulsen Anders , Sugden Robert , Tsutsui Kei
Published: October 2014

We investigate Schelling's hypothesis that payoff-irrelevant labels (“cues”) can influence the outcomes of bargaining games with communication. In our experimental games, players negotiate over the division of a surplus by claiming valuable objects that have payoff-irrelevant spatial locations. Negotiation occurs in continuous time, constrained by a deadline. In some games, spatial cues are opposed to principles of equality or efficiency. We find a strong tendency for players to agree on efficient and minimally unequal payoff divisions, even if spatial cues suggest otherwise. But if there are two such divisions, cues are often used to select between them, inducing distributional effects. (JEL C78, D63, D83)
Efficient Entry in Competing Auctions
Authors: Albrecht James , Gautier Pieter A. , Vroman Susan
Published: October 2014

In this paper, we demonstrate the efficiency of seller entry in a model of competing auctions in which we allow for both buyer and seller heterogeneity. This generalizes existing efficiency results in the competitive search literature by simultaneously allowing for nonrival (many-on-one) meetings and private information. (JEL D44, D82)
Private Equity Premium Puzzle Revisited
Authors: Kartashova Katya
Published: October 2014

This paper revisits the results of Moskowitz and Vissing-Jørgensen (2002) on returns to entrepreneurial investments in the United States. Following the authors' methodology and new data from the Survey of Consumer Finances, I find that the “private equity premium puzzle” does not survive the period of high public equity returns in the 1990s. The difference between private and public equity returns is positive and large period-by-period between 1999 and 2007. Whereas in the 2008–2010 period, overlapping with the Great Recession, public and private equities performances are substantially closer. I validate these results in the aggregate data going back to the 1960s. (JEL G11, G12, L26)
The Effect of Mergers in Search Markets: Evidence from the Canadian Mortgage Industry
Authors: Allen Jason , Clark Robert , Houde Jean-François
Published: October 2014

We examine the relationship between concentration and price dispersion using variation induced by a merger in the Canadian mortgage market. Since interest rates are determined through a search and negotiation process, consolidation weakens consumers' bargaining positions. We use reduced-form techniques to estimate the mergers' distributional impact, and show that competition benefits only consumers at the bottom and middle of the transaction price distribution, and that mergers reduce the dispersion of prices. We illustrate that these effects can be explained by the presence of search frictions, and that the average effect of mergers on rates underestimates the increase in market power. (JEL G21, G34, K21, L13, L41)
Importance of Non-Invasive Study of Microcirculation in the Limb at Assessment Amputation Level in the Patients with Critical Ischemia (Review)
Authors: Петриевский  , Petrievskiy S. , Сорока  , Soroka V. , Нохрин  , Nokhrin S. , Рязанов  , Ryazanov A. , Белоусов  , Belousov E.
Published: October 2014

The development of modern vascular surgery is impossible without improvement of diagnostic methods of examination. The development of severe disorders of blood circulation in limbs, beyond compensation, ends up executing amputation. In the present review the authors considered one of the current problems of modern vascular surgery - high amputation in patients with critical ischemia of lower extremities, the truncation of the leg. According to the majority authors, the main reason for early purulent - necrotic complications in high amputation is the mistake of determining the level of amputation. This fact is accompanied by a sharp reduction in the duration and quality of life, which entails increasing social burden and increases economic costs of rehabilitation of patients. One of the possible solutions to this problem is to study the safety regulatory mechanisms resistive Department microcirculation (arterioles, precapillary sphincters and metarterioles). This article presents the available arsenal of vascular surgery: methods of diagnostics of the microcirculation. It is proved the critical role of non-invasive methods for measuring microcirculatory disorders in critical limb ischemia (CLI) when the doctors choose the level of amputation. It is a comprehensive assessment of blood circulation in tissues and tissue metabolism allows to giving an objective answer on the degree of ischemic damage to the tissue in occlusive diseases of arteries of lower extremities.
The Vegetative Status Correction in the Patients with Chronic Dyscirculatory Encephalopathy on the Sanatorium Rehabilitation Stage
Authors: Куликов  , Kulikov N. , Череващенко  , Cherevashchenko Lyubov , Череващенко  , Cherevashchenko I.
Published: October 2014

Among vascular brain diseases a special place in its importance takes chronic cerebrovascular pathology in the form of dyscirculatory encephalopathy. The most frequently affected cerebral structures with discirculatory encephalopathy are those parts of the brain that are largely responsible for shaping over segmental vegetative disorders, which are characteristic of clinics chronic cerebrovascular insufficiency. The purpose of this work is to develop a new modern high technology of sanatorium rehabilitation of the patients with circulatory encephalopathy on stage I and to correct autonomic imbalance. The authors observed 60 patients who were divided into 2 groups. The control group received radon baths, the patients from the main group in addition to radon baths received laser therapy paravertebrally C1-Th3, according to scanning technique. In all patients before and after treatment the state of the autonomic nervous system studied. It was found that the initial manifestations of vascular encephalopathy accompanied by autonomic imbalance with a predominance of sympathetic tone, activation and inhibition effects of ergotrop activities segmental systems, primarily due to the parasympathetic division. The results of this study demonstrate feasibility of incorporating laser therapy in complex radon baths for rehabilitation of patients with circulatory encephalopathy autonomic imbalance. The findings suggest that improving the functional state mechanisms vegetative maintenance activities, which help to eliminate the state of surge and flow of adaptive reactions in the body.
The Study in Vitro the Virulence Properties and Resistance to Antimycotic Drugs of Fungi Candida Isolated from Children with Acute Intestinal Infection
Authors: Гладких  , Gladkikh P. , Серегина  , Seregina N. , Хренов  , Khrenov P. , Честнова  , Chestnova Tatyana , Маслов  , Maslov M.
Published: October 2014

This article presents the results of the study the virulence properties and antibiotic resistance of fungi of the genus Candida isolated from children with acute intestinal infection. Currently, there is an increase in the frequency of fungal infections, and the problem of resistance to antimycotic drugs is more important. The authors investigated 100 isolates of fungi of the genus Candida and they studied their virulent properties and conducted an analysis of resistance to antimycotic drugs. The correlation of the strains had the following values: leading species is C. albicans – 78.6%, then followed C. kruzei, C. glabrata, C. tropicalis (10,6, 7,1 and 3,6% respectively). In most cases the species of fungi Candidaspp. were determined in the intestine in the composition of associations with other members of pathogenic and conditionally pathogenic microflora. The study of the virulence properties of mushrooms allowed to obtain the following data: the ability to filamentation was detected in 100% of tested strains C. albicans, C. krusei – 36% of strains, and the strains of C. glabrata and C. tropicalis has not shown the ability to filamentation. Analysis of antibioticogram of fungi demonstrates the following results: 100% of strains of C. krusei are resistant to fluconazole (this type of natural resistant to the drug), to voriconazole 14% of the strains, and to flucytosine, to amphotericin B 11% and 34%, respectively. Intermediate sensitivity to amphotericin B was observed in 11% of the isolates. The authors revealed the presence of strains of C. krusei associated with resistance (40%) and strains with cross-resistance to 11%. The increase in the minimum overwhelming concentration of antimycotics in strains of C. kruseiс and the associated cross-resistance is observed. 100% of strains of C. tropicalis, and C. glabrata are sensitive to all four drugs.
Ultrasonic and Laser Therapy in Treatment of the Plantar Warts
Authors: Шустов  , Shustov S. , Портнов  , Portnov V. , Корчажкина  , Korchazhkina N. , Котенко  , Kotenko K.
Published: October 2014

This paper presents the data on efficiency of ultrasonic therapy with Interferon and laser therapy in treatment of patients with vulgar warts. The authors studied the effectiveness of the ultrasonic and laser therapy in treatment of patients with clinical manifestations of papilloma virus infection. The examination involved 32 patients aged from 16 to 65. The duration of the disease varied from 2 months to 3 years. After ultrasonic and laser therapy it was established the normalization of laboratory indices. Relapses were absent in 32 patients. Adverse side effects didn’t register during the investigation. The use of ultrasonic and laser therapy allows to carry out highly effective therapies in treatment of patients with human papilloma virus disorders, and to decrease the risk of relapse of infection.
Laser and Ultrasound Therapy in the Treatment of Rosacea
Authors: Орлова  , Orlova E. , Круглова  , Kruglova L. , Котенко  , Kotenko K.
Published: October 2014

The data on efficiency of the combined application of pulse laser and ultrasonic therapy in the treatment of patients with rosacea are presented. It is shown that this method has high efficiency concerning all clinical symptoms of a disease, especially, positive effect on a vascular component rosacea.
Changing Spatial Structure in the Rocky Mountain Regional System
Authors: Elliott Harold M.
Published: October 2014

Using cardinal neighbor analysis, where each place in a region is linked with its nearest larger neighbor, it has been found that between 1940 and 1980 the linkage structure defining the Denver, Colorado, regional system changed at a rate of 11.5 percent per decade. Within the five-state area constituting the Denver system, Wyoming exhibited the greatest amount of structural change (14.9%) while Utah exhibited the least (7.7%). Observed change rates can be explained by the size of a subject place relative to its nearest larger neighbor and the presence or absence of intervening large places. Spatial change is thus related to prior spatial structure.
Suburban Commercial Development in the Shadow of Downtown Sacramento
Authors: Hardwick Susan Wiley
Published: October 2014

Sacramento, like most other metropolitan areas today, has its share of historic suburbs. Immediately west of the city, the suburban region of East Yolo has been isolated from Sacramento's downtown for over a century and continues to lie in the shadow of the central city's shopping district. East Yolo's commercial patterns reflect a cycle of optimism, then pessimism, as great expectations were followed by great disappointments. Early land developers' promises of a "Parisian style suburb" have, in fact, resulted in a blue-collar district of small homes on small lots. During the freeway era, new transportation routes bypassed the area's economic development. This suburban region is once again optimistic as developers envision elaborate marina projects, replacing former blighted commercial landscapes. Business inventories for critical years during the boom and bust cycles illustrate the above processes of commercial change in suburban Sacramento.
Church of the East from Ancient Times through World War I
Authors: Smith Gary Neil , Grivetti Louis Evan
Published: October 2014

The Church of the East is a Christian diophysite sect whose emergence in the Middle East can be understood in the light of theological controversy and geopolitical circumstances in early Christian times. Isolation of the Church of the East enabled it to play an important role in the preservation of classical learning. Church of the East missionaries helped spread Christianity to China and India. Geopolitical and ethnic conflict in the twentieth century has led to new Church of the East (now sometimes referred to as "Assyrian" Christian) locational patterns in the Middle East and significant migration to other parts of the world, including California.
The Growth of the Mexican Wine Industry
Authors: Crowley William K.
Published: October 2014

Mexico's wine history reaches more than four and a half centuries into the past, but because of Spanish restrictions wine production suffered during much of the colonial period. The disinterest in wine resulting from these restrictions continued until the 1970s when a worldwide revolution in winemaking and viticulture reached Mexico. Modern viticultural methods, improved grape varieties, and high technology winemaking equipment and practices were introduced. New areas were planted to wine grapes, older districts expanded their plantings, and new wineries were constructed. Although the amounts of wine made still are quite modest, winemaking is spread among a surprisingly large number of vineyard regions in the northern two-thirds of the country. The greatest efforts are concentrated in Baja California, which produces 70 percent of Mexico's table wine, even though it is the most distant vineyard district from the country's dominant market in Mexico City. Despite great relative growth in volume and quality in the late 1970s and early 1980s, the Mexican wine industry faces considerable barriers to further growth and improvements.
DNA Ligase-Based Strategy for Quantifying Heterogeneous DNA Methylation without Sequencing
Authors: Wee Eugene J H , Rauf Sakandar , Shiddiky Muhammad J A , Dobrovic Alexander , Trau Matt
Published: October 2014

BACKGROUND

DNA methylation is a potential source of disease biomarkers. Typically, methylation levels are measured at individual cytosine/guanine (CpG) sites or over a short region of interest. However, regions of interest often show heterogeneous methylation comprising multiple patterns of methylation (epialleles) on individual DNA strands. Heterogeneous methylation is largely ignored because digital methods are required to deconvolute these usually complex patterns of epialleles. Currently, only single-molecule approaches, such as next generation sequencing (NGS), can provide detailed epiallele information. Because NGS is not yet feasible for routine practice, we developed a single-molecule–like approach, named for epiallele quantification (EpiQ).

METHODS

EpiQ uses DNA ligases and the enhanced thermal instability of short (≤19 bases) mismatched DNA probes for the relative quantification of epialleles. The assay was developed using fluorescent detection on a gel and then adapted for electrochemical detection on a microfabricated device. NGS was used to validate the analytical accuracy of EpiQ.

RESULTS

In this proof of principle study, EpiQ detected with 90%–95% specificity each of the 8 possible epialleles for a 3-CpG cluster at the promoter region of the CDKN2B (p15) tumor suppressor gene. EpiQ successfully profiled heterogeneous methylation patterns in clinically derived samples, and the results were cross-validated with NGS.

CONCLUSIONS

EpiQ is a potential alternative tool for characterizing heterogeneous methylation, thus facilitating its use as a biomarker. EpiQ was developed on a gel-based assay but can also easily be adapted for miniaturized chip-based platforms.
Modern antiquity: An introduction to Athenian metropolitan modernity
Authors: Giannakopoulou Georgia
Published: October 2014

This essay discusses the ways in which an idealized image of classical Athens contributed towards the formation of a city in which the coexistence between the ancient and the modern, old and new convey a unique urban experience. This ‘modern antiquity’, or the socially constructed and aesthetically perceived image of the city’s past as exclusively classical was promoted by a number of different actors, from German classicists who never visited Greece, English and French travellers, to Greek governments and communities of city dwellers. The essay focuses on the role of the latter two categories in the building of modern Athens and explores three spheres where the emphasis on antiquity redefined the city’s past and hindered its modernization, namely royal decrees, local and national governmental obstructions to an organized city plan, and the various perceptions of the city’s concrete apartment buildings.
Vitalization and spectacle in Thanassis Rentzis’s Bio-Graphia and Corpus
Authors: Vassiliou Konstantinos
Published: October 2014

Thanassis Rentzis’s work offers an investigation into the nature of the cinematic medium and the constellations of industry, spectacle and subjectivity, most explicitly demonstrated in two films he made in the 1970s, Bio-Graphia (1975) and Corpus (1979). Largely influenced by collage and pre-cinematic techniques, these are the most essayistic of Rentzis’s films and they set out to trace human sensibilities that were central to the rise of audio-visual culture. Their main themes concern the fragmentation of representation in modernity, and correspondingly, a mutual constitution of the audio-visual with interactions throughout social life. The article will argue that the films do not insist on spectacle as a negation of life, but on a vitalist approach of audio-visuality whereby the dissemination of images relies on physiological and perceptual modes of spectatorship.
‘Fight Together/Write Together’: Street art as documentation of affect in times of unrest in Athens
Authors: Chiotis Theodoros
Published: October 2014

This visual essay attempts to map how evolving feelings of unrest have been captured in slogans and street art painted on the walls of Athens over the past few years. Slogans and street art demarcate alternative spatialities and alternative subjectivities within the city limits. In effect, slogans and street art function as signs of a community struggling to articulate itself in the face of political stagnation; ontology, politics and art thus become intimately entwined. Street art and graffiti are collective gestures of desire, movement and flux coming from a loosely defined collective of artists and amateurs making use of their artistry to create works which comment, disrupt and create alternative ways of building communities and subjectivities.
A shifting landscape: Contemporary Greek dance and conditions of crisis
Authors: Panagiotara Betina , Tsintziloni Steriani
Published: October 2014

This article introduces a framework for discussing contemporary dance’s potential for critical intervention within the context of the current socio-economic crisis in Europe, focusing on examples from Greece. In particular, it explores how the use of history in recent works proposes new engagements and relationships between past and present, inviting a reconsideration of the past while making possible the envisaging and articulation of emergent narratives, identities and social formations. It also examines the use of collaborative practices for choreographing, which depart from hierarchical dance processes that have been dominant in Greece and thus challenge the prevailing perception of danse d’auteur while exploring different modes of production. The significance of these practices lies in their questioning of previously established modes of working but also in their potential function as models of broader social practices. The works in question are analysed not as artefacts alone but as artistic practices that operate, act and interact within the social, the political and the aesthetic. It is argued that under conditions of socio-political crisis, the established social order is renegotiated and that these works, through the practices with which they engage, are significant in the reconstitution of the social. Thus, they propose a way of reclaiming the social dimension and potential of the arts in a period when their role is disputed.
The militant subject as tragic hero in Dimitris Nollas’s fiction
Authors: Petsa Vasiliki
Published: October 2014

This article focuses on the militant subjects in Dimitris Nollas’s fiction and considers them as tragic heroes that occupy liminal positions. Political violence, as a contested tactical option of militancy, posits pressing dilemmas and generates intricate explorations of morality and agency. After sketching a brief theoretical framework in order to assess recent theories of the tragic, I focus on the novella To Pempto Genos / The Fifth Age (Nollas, 1988) and the novel O Anthropos pou Xehastike / The Man in Limbo (Nollas, 1995) in terms of conflictual memory frames and ethical stances. Although they present similarities on the thematic level, a close reading of the texts elucidates the different approaches taken towards the militant past from the present standpoint and, consequently, the divergent implications for the future.
Lyrical stresses of heavy metal and rap
Authors: Geliebter David , Ziegler Ari J. , Mandery Evan
Published: October 2014

Two hundred and ten college students were played either a rap or heavy metal version of a song and surveyed to determine lyrical recollection and comprehension of the song’s themes. Students who heard the heavy metal version paid less attention to the song’s themes and had worse lyrical recollection. This data strengthens the argument that heavy metal music has a lesser lyrical stress than rap. Consequently, a ‘gangsta’ heavy metal song is less likely to be repeated, taken to heart and acted upon than a gangsta rap song. This finding offers important support for a non-race-based theory explaining the disproportionality between criticism of gangsta heavy metal music and gangsta rap music.
‘Oil complex’ and social responsibility theory of the media: Shaping Nigeria’s environmental discourse with social media
Authors: Uzoechi Nwagbara
Published: October 2014

The aim of this article is to explore how social media can be used to effectively bring behavioural change and rational opinion about ‘oil complex’ in Nigeria’s Niger delta region for a more sustainable future. Second, this article argues that social media can also be used as a medium to shape public opinion, pluralistic views and policy agenda about challenges posed by ‘oil complex’. This process resonates with the social responsibility function of the media. While mainstream or traditional media perceptibly steer clear of reporting issues that highly challenge corporate interests, which have strong links with these media outlets, social media can be a platform for critical and balanced reportage of social and environmental issues for diversity of views to be aired. The media’s role in this sense will help manage problems associated with ‘oil complex’ for a more sustainable future in the region.
Mobile phone users from low socio-economic strata in Asia: The moderating roles of age and gender
Authors: Maity Moutusy
Published: October 2014

This article investigates the continued usage of mobile telecommunication services (voice services and short messaging services (SMS)) among users from low socio-economic groups in Asia, and also examines the moderating effects of demographic variables age and gender on the intention to continue using these services. We investigate the phenomenon of information obtained using voice-based services and non-voice-based services by users from low socio-economic groups. This investigation brings together the Technology Acceptance Model (TAM) framework, and the information search paradigm to suggest a model for continued use of mobile phones. Data collected from individual telecommunication users across five South East Asian countries are analysed through structural equation modelling (SEM) to test the hypotheses. Findings demonstrate that for voice services, perceived ease of use (PEU) significantly affects intention in younger users (and not older users), while usefulness is a stronger predictor of intention for older users. For users of voice services and SMS, PEU significantly affects intention in males only, while subjective norm significantly affects intention only in females. From a public policy perspective, a greater emphasis may be placed on disseminating information about the benefits of mobile telecommunication among potential mobile phone users through groups that influence user behaviour.
Actualistic Zooarchaeology in Central Western Argentina in Cave and Open Air Contexts
Authors: Otaola Clara
Published: October 2014

Many cultural and natural processes form the archaeological record. Taphonomy, the study of the transition of organic matter from living contexts (the biosphere) to geological contexts (the lithosphere), aids in understanding how agents and processes affect skeletal remains in the archaeological record. In this paper the results of an actualistic taphonomic study on deposition of bones in open-air and cave contexts in the high elevation Andes Mountains are presented. Results indicate that within the first three months after deposition many bones are displaced or removed from sites and that the agents that act in each context are different. Horizontal displacement of bones from their deposited locations is limited in the cave context but is dominant in the open air site. Carnivores appear to be responsible for moving bones in open-air contexts, and rodents appear to displace bones vertically in the cave context. Such naturalistic experiments are important in particular areas of the world in which local taphonomic processes vary.
Secret Chambers: The Insider Story of Cells and Complex Life
Authors: Pazhoohi Farid
Published: October 2014

Review of Secret Chambers: The Insider Story of Cells and Complex Life. Martin Brasier. 2012. Oxford University Press, UK. Pp. 320 with 15 black and white illustrations and 8 pages of color plates. £16.99 (hardcover). ISBN 9780199644001.
Hematopoietic stem cell transplantation completely reversed colitis but not arthritis in IL-10Rα deficiency
Authors: Kim Vy H.D. , Brager Rae , Upton Julia , Ngan Bo , Newell Andrea , Roifman Maian , Muise Aleixo M. , Benseler Susanne M. , Grunebaum Eyal , Roifman Chaim M.
Published: October 2014

Mutations in IL-10R1, IL-10R2, and IL-10 have been identified in infants with severe colitis. The only possible hope for cure in these conditions is a hematopoietic stem cell transplantation (HSCT). We report here on a patient with IL-10R1 deficiency who suffered severe colitis and arthritis. She received a HSCT from a matched unrelated donor and her post-transplant course was uneventful. She has fully engrafted and her immune reconstitution was complete and robust. Although signs of colitis were completely resolved, arthritis was not reversed by HSCT. She continues to have joint swelling in the knees and inflammatory changes in the wrists. In conclusion, HSCT seems to have reversed colitis, but was insufficient to improve arthritis and possibly other autoimmune manifestations.

Statement of novelty: This report describes a successful HSCT in severe infantile colitis caused by mutations in IL-10R1. Yet, the arthritis remains active, suggesting that conditions such as severe rheumatic disorders in childhood may not be reversed by replacement of the hematopoietic system.