bluuebunny/crossref_metadata_2025 huggingface dataset:
Compuestos bioactivos en quesos: biosíntesis, actividad biológica y contribución de las bacterias ácido lácticas
Authors: López-Mendoza Joel , Adriano-Anaya Lourdes , Gálvez-López Didiana , Vázquez-Ovando Alfredo
Published: March 2023

Introducción. A partir de 1990 se ha observado un incremento en la tasa de enfermedades asociadas con dietas poco saludables y estilos de vida sedentaria, cuya atención supone un reto para los sistemas de salud. Lo anterior, ha despertado el interés por los alimentos funcionales, es decir, aquellos que además de proporcionar macro y micronutrientes, aporten sustancias que poseen efecto fisiológico en el organismo, lo que se traduce en la mejora de la salud de quien lo ingiere. De manera genérica a estos compuestos se les conoce como bioactivos. Objetivo. Revisar las principales sustancias bioactivas reportadas en quesos, el papel de los microorganismos en la producción de las mismas y las rutas de biosíntesis de los principales compuestos. Desarrollo. La leche y sus derivados son productos alimenticios consumidos alrededor del mundo y presentan un incremento constante en su producción y consumo. Esta tendencia de mercado es debida a su sabor y aporte nutrimental. Uno de los derivados lácteos con mayor demanda en el mundo son los quesos. Son una fuente de sustancias como péptidos, ácidos grasos, vitaminas, bacteriocinas, ácidos orgánicos, ácido gamma aminobutírico, etc., todas con importante actividad biológica. Conclusión. La presencia, cantidad y disponibilidad de los compuestos bioactivos presentes en los quesos difiere, como resultado del tipo de leche empleada para su elaboración, el tipo de microorganismo empleado, ya sea como cultivo iniciador o secundario, así también como el proceso tecnológico empleado.
Condiciones del trabajo informal en seguridad privada: perspectivas desde el migrante nicaragüense
Authors: Mora Izaguirre Cynthia , Vargas Loáciga Carlos , Hernandez Murillo Jason , Rodríguez González José Isaac
Published: March 2023

Introducción: El presente estudio muestra las percepciones que tienen los llamados «Guachimanes» acerca de sus condiciones laborales de informalidad en el campo de la seguridad en Costa Rica. A pesar del cargo tan importante que desempeñan estas personas y de la alta percepción de inseguridad en el país, poco se conoce acerca de quiénes se encargan de la seguridad de los espacios físicos y mucho menos de cuáles son sus condiciones laborales.

Objetivo: El artículo explora las experiencias en las condiciones de trabajo informal en el campo de la seguridad privada del migrante nicaragüense, para poder así describir algunos temas claves desde sus propias vivencias de tal manera que se pueda evidenciar y reflexionar acerca del ambiente de trabajo además de carencias en sus derechos laborales.

Método y técnica: Este estudio es de carácter exploratorio y de naturaleza cualitativa. Los datos fueron compilados a través de un instrumento metodológico de entrevistas semiestructuradas en distintos barrios de la Gran Área Metropolitana (GAM), elegidos mediante un rastreo en el campo, se buscaba directamente barrios de clase media alta en los que estuvieran presentes las casetillas las cuales vienen a ser el lugar de trabajo de las personas encargadas de la seguridad de los espacios físicos.

[Continúa leyendo en el artículo]
Aproximaciones temáticas de los estudios ambientales sobre la actividad artesanal: argumentos para su estudio en México
Authors: Farfán Escalera Ricardo , Pérez-Ramírez Carlos Alberto , Romero Aguilar Mariana
Published: March 2023

Introducción: Las diferentes vertientes que puede tomar el estudio de la actividad artesanal y su relación con el medio natural han representado un importante reto debido a la diversidad de pensamientos expresados, lo que conlleva un esfuerzo heurístico para identificar elementos explicativos que tuviesen puntos de encuentro suficientes y permitieran establecer una clasificación pertinente.

Objetivo: La investigación tuvo como objetivo documentar las orientaciones temáticas que enmarcan los estudios ambientales de la actividad artesanal, esto mediante la revisión de distintas investigaciones que han abordado la relación entre artesanía y naturaleza.

Método: Para ello, se llevó a cabo un análisis crítico del acervo bibliográfico identificando las orientaciones temáticas. La indagación se realizó tras el estudio de artículos científicos publicados en revistas indizadas, durante el periodo 2007 a 2022 y disponibles en acceso abierto en idioma español, inglés y portugués; además se consideraron los siguientes criterios: tipo de investigación, objetivo de la contribución, enfoque metodológico, ámbito territorial, orientación temática y disciplinaria.

Resultados: Se identificaron cuatro grupos de aproximaciones temáticas: a) proceso de producción, acceso a materias primas, transformación y tecnologías; b) impacto de la producción sobre los recursos naturales; c) formas de organización social en el contexto local; d) comercialización y consumo en el mercado actual.

Conclusiones: Si bien es posible establecer una propuesta de clasificación de los estudios ambientales de las artesanías, se requiere una visión ampliada de la realidad que supere las perspectivas parcelarias, y se consideren los paradigmas propios de la complejidad como argumentos para su estudio en México.
La ciudadanía republicana como alternativa para el desarrollo democrático en el siglo XXI
Authors: Pérez-Verduzco Germán
Published: March 2023

Introducción: En el presente artículo de reflexión se plantea que, por sus características, el modelo de ciudadanía republicana es la mejor alternativa para promover la participación ciudadana en las democracias occidentales contemporáneas.

Objetivo: El propósito del texto es analizar las ventajas de la ciudadanía republicana respecto a otros modelos, así como explicar las razones por las que se le considera el enfoque más adecuado para el desarrollo teórico y práctico de la participación ciudadana.

Método: Para su elaboración, se recurrió al método de investigación documental. En cuanto a la estructura del artículo, primero, se presenta el debate entre las visiones de democracia representativa y democracia participativa; posteriormente, se examina la influencia de los paradigmas realista e idealista como corrientes filosóficas políticas que subyacen y sustentan las principales premisas de ambas perspectivas de democracia. Al final, se describen los modelos de ciudadanía liberal, comunitarista y republicana, así como sus implicaciones para la participación ciudadana.

Resultados: Del análisis realizado se concluye que el modelo de ciudadanía republicana permite superar la dicotomía representación-participación, además de brindar un cimiento más sólido y congruente tanto a la teoría como a la praxis del involucramiento ciudadano en los asuntos públicos.
Políticas de Comunicación y Género en Argentina. 28 años después de Beijing
Authors: Rodriguez Maria Florencia
Published: March 2023

Introducción: En 1995, en el marco de la IV Conferencia Mundial sobre la Mujer, representantes de gobiernos de todo el mundo acordaron la Plataforma de Acción de Beijing. Los medios de comunicación aparecen, por primera vez, como una de las esferas de especial preocupación para lograr la igualdad de género en el mundo.
Objetivo: Realizar un monitoreo crítico sobre las políticas de comunicación y género desarrolladas por el Estado argentino en torno al cumplimiento de los objetivos estratégicos planteados en el capítulo J: participación de las mujeres en la estructura laboral de los medios; y erradicación de contenido mediático sexista y estereotipado.
Método y técnicas: Se desarrolló una investigación documental con enfoque cualitativo y se utilizó la técnica del análisis de contenido. A partir de esto, especialmente para la elaboración de conclusiones y recomendaciones, se tomó como referencia una metodología para el análisis de género del fenómeno legal.
Resultados: La mayoría de las políticas impulsadas por el Estado argentino cumplen con el segundo objetivo estratégico de la Plataforma de Acción de Beijing. En el año 2021 se sancionó una ley de equidad de géneros en los medios que responde al primer objetivo estratégico, sin embargo, todavía no fue reglamentada.
Conclusiones: Existen desafíos pendientes en relación con posibles reformas en la normativa vigente sobre violencia contra las mujeres; las tensiones entre regulación y libertad de expresión; el acceso a la justicia en casos de violencia mediática; y la necesidad de avanzar en el cumplimiento del objetivo estratégico uno.
Impacts of human capital, the fourth industrial revolution, and institutional quality on unemployment: An rmpirical study at Asian countries
Authors: Tran Oanh , Le Trung Dao , Phan Thi Hang Nga , Huynh The Nguyen
Published: March 2023

By using the combination of several regression techniques on panel data, this study explores the influence of human capital, institutional quality, and the Fourth Industrial Revolution on unemployment rates in 46 Asian countries during the period from 2007 to 2020. According to the generalized method of moments (GMM), there are a total of 9 factors affecting the unemployment rate in the researched model, including high-tech exports, inflation, population, gross domestic product, government spending, foreign debt, foreign direct investment, human capital, and institutions. This result confirmed that high-tech development increases unemployment in Asia; however, the nexus between human capital and institutional situation with the unemployment rate is different based on the particular fields. Moreover, some policy implications also have been suggested to reduce unemployment in Asian countries in the context of the Fourth Industrial Revolution.
The role of emotional intelligence and cross-cultural adjustment on job performance of self-initiated expatriates with origins from Central Asian countries
Authors: Abdyrakhmanova Kaiyrkul , Poór József
Published: March 2023

The current empirical study observes the impact of Emotional Intelligence (EI) and Cross-Cultural Adjustment (CCA) on Job Performance (JP) particularly Task Performance (TP) and Contextual Performance (CP) of Self-Initiated Expatriates (SIE) located in Central-Eastern Europe countries. The PLS SEM technique was implemented to analyze the data from a survey of 314 self-initiated expatriates. The findings showed that Emotional Intelligence has strong impact on CCA and Task Performance. As to CCA it has an influence on contextual performance. Considering that there have been few empirical investigations on the influence of Emotional Intelligence and cross-cultural adjustment on job performance of self-initiated expatriates, the insights gained from current study will contribute to the body of knowledge in the field of expatriate research, particularly in the areas of international human resource management and cross-cultural management. The practical significance of the findings will be valuable to HR professionals and multinational companies, especially in the area of expatriate selection, recruitment, and intercultural training and development.
Cadeau de fiançailles byzantin d’une princesse normande ? (cod. Iviron 463 [Lambros 4583])
Authors: Egedi-Kovács Emese
Published: March 2023

The manuscript Iviron 463 contains the Greek version of the Barlaam and Joasaph Romance. Apart from the beautiful miniatures in the codex, it is also special because of a complete, heretofore not transcribed Old French translation running through the margin of the manuscript. The uncommon bilingual manuscript is of significant importance not only from the perspective of Old French philology but also from the perspective of linguistic and literary interactions between cultures. This paper examines the circumstances of the creation of the manuscript and the questions related to the commissioner in more detail.
ANALISIS SPASIAL DAN TEMPORAL TERHADAP ALTERNATIF STRATEGI PENGELOLAAN PERIKANAN IKAN KEMBUNG DI PERAIRAN SELAT SUNDA
Authors: Kuswoyo Agus Heri , Mualim Rahmat
Published: March 2023

Tujuan dari penelitian ini adalah memetakan distribusi sebaran spasial dan temporal kegiatan perikanan terkait pertumbuhan populasi ikan dan strategi pengelolaannya. Terkait hal ini, Rastrelliger, terpilih sebagai spesies yang ditangkap di wilayah pengelolaan perikanan yang dikenal memiliki nilai ekonomi tinggi meskipun sebagai bycatch. Untuk Dalam menentukan strategi pengelolaan spesies ini, pemetaan merupakan langkah penting pertama dari kegiatan yang harus dilakukan. Pada bulan Januari sampai dengan Maret 2016 dilakukan Penelitian ini di Tempat Pendaratan Ikan (PPP) Labuan, Lempasing, dan Kota Agung dengan melakukan survey yang dilakukan melalui wawancara, purposive sampling dan stratified random sampling untuk sampel ikan. Hasil penelitian ini menegaskanadanya tumpang tindih wilayah penangkapan ikan,berdasarkan irisan satu fishing ground dengan penangkapan nelayan yang berbeda wilayah penangkapan yaitu di perairan Pulau Legundi, Belimbing, dan Kilauan. Korelasi antara bobot panjang Rastrelliger memilikipola alometrik negatif dalam pertumbuhan, ikan dewasa Rastrelliger kanagurta dengan ukuran kelas 18,03–22,09 cm (jantan) dan 19,10–19,52 (betina) dengan ukuran tangkapan pertama (Lc) menggunakan purse seineadalah 15,66 cm dan 18,67 cm (Lc<Lm artinya ikan tidak bertelur saat ditangkap). Alternatif strategi pengelolaan yang tepat adalah penutupan penangkapan disaat musim penangkapan untuk memberikan kesempatan bagi ikan untuk memijah.
Collaborative Problem-Solving in Mathematics: A Systematic Literature Review
Authors: Fatmanissa Namirah , Yuli Eko Siswono Tatag , Lukito Agung , Budi Rahaju Endah , Ismail Ismail
Published: March 2023

This study aims to explore the definition, task characteristics, and themes in studies of CPS in mathematics. An SLR was conducted on articles from 2002-2022 using Scopus database. The thematic analysis identified five themes of studies: Technology, Discourse analysis, Social Skills, Mathematical thinking, and Students‘ achievement. Research gaps and potential future studies within each theme were explored.
The crystallization of thin Sb2Te films with vacuum annealing and an electron beam
Authors: Yushkov Anton A. , Kolosov Vladimir Yu.
Published: March 2023

Thin Sb2Te films with a thickness gradient were studied via transmission electron microscopy. The processes of forced crystallization were examined with thermal annealing and an electron beam. The crystallization’s general tendencies, including competitive nucleation and growth crystallization, were revealed. As the thickness of the sample increases, the size of the crystals growing in the film enlarges. As the temperature increases, the number of crystals in the film grows. Crystallization under the action of an electron beam occurs mainly by nucleation mechanism.
The Role of Early Literacy Skills in Beginning to Read in Turkish: Longitudinal Findings from First Graders
Authors: KARGIN Tevhide , GÜLDENOĞLU Birkan , GENGEÇ Hilal
Published: March 2023

The aim of this longitudinal study is to investigate the effects of early literacy skills on beginning to read in a transparent orthography, viz. Turkish. In line with this aim, a total of eighty-four participants were followed from preschool to the end of the first grade and the extent to which participants' early literacy skills in the preschool period predict their future reading performances was examined. All the data gathered in the study were collected individually at one-year intervals. The participants’ early literacy skills were tested by the "Test of Early Literacy (TEL)", reading comprehension skills was obtained with a text containing 162 words and 10 multiple choice questions, reading fluency performances were calculated with the formula of correct number of words per minute. Data were computed through correlation analysis, and hierarchical regression analysis. Results suggest that regarding phonological awareness, early literacy sub-skills, especially those contributing to or serving oral comprehension had positive effects on reading fluency and reading comprehension at the end of the first grade. Valuable conclusions have been drawn from this finding about the role of phonological awareness, and its contribution to reading in an agglutinative orthography such as Turkish. Obtained results are discussed in relation to the literature.
TABLE-seq for strand-specific RNA sequencing v1
Authors: zhang Yanjun
Published: March 2023

This protocol utilizes the Tn5, a widely used transposase, to perform single-strand DNA sequencing. Tn5 can tagment single-strand DNA and ligate transposon cargo to the 3’ end. We developed a tagmentation-based and ligation-enabled single-strand DNA sequencing method called TABLE-seq. The method below is an example to use TABLE-seq to conduct strand-specific RNA sequencing.
ACTION Biomarker Study v1
Authors: A. Hagenbeek Fiona
Published: March 2023

The goal of ACTION project (Aggression in Children: Unraveling gene-environment interplay to inform Treatment and InterventiON strategies) was to identify precursors, features, and consequences of childhood aggression using epidemiological and omics-driven studies. A considerable effort within ACTION was the collection of new omics data in children with low and high aggressive behavior. To this end, the ACTION project included large-scale collection of biological samples in children from the Netherlands Twin Register (NTR), a twin cohort from the general population, and a cohort of children referred for psychiatric treatment (LUMC-Curium). Together these cohorts comprise the ACTION Biomarker Study. This documentation describes the study design and data collection for the ACTION Biomarker Study.
Effects of Intellectual and Social Alignment on Organizational Agility: A Configurational Theory Approach
Authors: Hu Hao ,   Jiangsu University of Science and Technology, Wang Nianxin ,   Jiangsu University of Science and Technology, Liang Huigang ,   University of Memphis
Published: March 2023

Literature has shown that business-information technology (IT) alignment can exert both positive and negative influences on organizational agility, giving rise to the IT alignment-agility paradox. To better understand this paradox at a more granular level, we conceptualize the sensing and responding dimensions of organizational agility as two independent constructs and suggest a nonlinear analytical approach. Based on configurational and contextual perspectives, this study investigates how intellectual and social alignment and organizational and environmental elements combine into multiple configurations to affect sensing and responding capabilities. Fuzzy-set qualitative comparative analysis (fsQCA) is used to analyze the survey data from 135 dyads of business and IT executives from the Chinese shipbuilding industry. Results show that different equifinal pathways can be used to achieve high sensing and responding capabilities, in which intellectual and social alignment play heterogeneous roles depending on the specific contexts. This study extends the ITenabled agility literature by deepening our understanding of the effects of multidimensional IT alignment on multidimensional organizational agility and providing new insights into the IT alignment-agility paradox.
Seasonal Variations of Seismic Travel-Time Changes in Binchuan, Southwestern China, Inferred from Large Volume Air-Gun Source Array Data
Authors: Luan Yi , Yang Hongfeng , Wang Baoshan , Yang Wei , Wang Weitao , Yang Jun , Li Xiaobin , Ran Jiangjun
Published: March 2023

Active sources, especially air-gun sources in the water reservoir, have proven to be powerful tools for detecting regional scale velocity changes. However, the water level change affects the repeatability of the air-gun waveform and, thus, affects the stability of the detection of the velocity changes. This article explores how to make full use of the air-gun signals excited at different water levels from analyzing three years of air-gun data recorded by 20 stations deployed from ∼50 m to ∼25 km from the source. At the same time, by utilizing the poroelastic model, we quantify both vertical and horizontal distances affected by the water level change. More important, supported by the strain data from one borehole strainmeter station, the influence mechanisms of the seasonal variation derived from the three years of air-gun data are also discussed. Results indicate the water level affects the main frequency of the air gun and has a strong influence on the coda wave. When the water level of the reservoir changes abruptly, the dominant effect on the derived delay time change is from the water level change. In this case, the deconvolution method can hardly eliminate the influence of the abrupt water level change. However, when the reservoir's water level changes gently, the delay time varies accordingly rather than inversely with the water level. Other reasons affect the material properties and, thus, influence the derived delay time. The modeled vertical component of poroelastic strain caused by the reservoir water level change is 1×10−7. The observed strain (4×10−7) from the strainmeter is likely associated with thermoelastic strain induced by temperature change. Our results show that although the long-term air-gun signal is affected by water level, there is still much information about changes in the subsurface that is worth mining.
Pyseistr: A Python Package for Structural Denoising and Interpolation of Multichannel Seismic Data
Authors: Chen Yangkang , Savvaidis Alexandros , Fomel Sergey , Chen Yunfeng , Saad Omar M. , Oboué Yapo Abolé Serge Innocent , Zhang Quan , Chen Wei
Published: March 2023

New sensing techniques like the nodal geophones and distributed acoustic sensing enable a spatial sampling ratio that was unprecedentedly high in earthquake seismology. The much higher sampling of seismic wavefields that is close to the level in exploration seismology calls for a unified processing approach for multichannel seismic data regardless of the research interest, for example, oil and gas oriented or earthquake-study oriented. Here, we present the first Python package for multichannel seismic data that benefits both communities, that is, exploration and earthquake seismology, called Pyseistr. The Pyseistr is a Python package that is designed to make full use of the structural patterns in multichannel seismic data to facilitate the data processing. The Pyseistr package currently includes several fundamental functions like slope estimation, structural mean and median filtering, and structural reconstruction of missing data. The Pyseistr package is continuously developed to include more functions that benefit both exploration and earthquake communities.
Seismic Monitoring of Novaya Zemlya: Progress, Challenges, and Prospects
Authors: Kværna Tormod , Dando Ben David Edward , Gibbons Steven John
Published: March 2023

The permanent seismic stations of the European Arctic maintain a detection threshold of around magnitude 2 for events on and around Novaya Zemlya. Events above magnitude 3 are clearly observed by multiple stations at regional and far-regional distances and, with improved travel-time models, can be located with high accuracy. The monitoring capability for smaller magnitude events is dominated by the small aperture seismic arrays ARCES and SPITS. We review the properties of Novaya Zemlya seismic signals on key stations and discuss how empirical signal processing may enhance detection and interpretation of future events in the region. We present a joint probabilistic location for 21 low-magnitude events between 1986 and 2020 in which the joint probability distribution for all events simultaneously exploits both constraints on earlier events from stations no longer in operation and constraints on newer events from more recently deployed stations. Advances in signal processing, enhanced exploitation of archive data, new permanent stations, and comparative multiple event analysis will all contribute both to a more robust and sensitive detection capability and higher confidence in signal interpretation.
The genetics of human severe pediatric gastroensophageal reflux disease
Authors:   , Hu Fen Ze , Ehrlich Garth D
Published: March 2023

We recognized that severe pediatric gastroesophageal reflux disease (GERD) is familial and follows an autosomal dominant pattern of inheritance. GER is the retrograde movement of stomach contents into the esophagus, and is a major etiological factor in respiratory diseases, and disorders of the ears, nose, and throat. Severe GERD affects approximately 2% of children, but it is currently under diagnosed. A subject population for mapping was obtained through the auspices of the Pediatric/Adolescent Gastroesophageal Reflux Association from which a group of multiplex families was ascertained. A genome-wide scan performed at a resolution of 8 centiMorgans (cM) identified a 16 cM GERD locus on chromosome 13q with a multifamily LOD > 4. Analyses of additional meioses, fine mapping studies, and the human genome sequence were used to reduce the locus to 6 megabases and increase the multifamily LOD > 7. A multi-pronged strategy including candidate gene analyses, high throughput DNA sequencing, and SNP-based association studies, was employed to positionally clone the GERD gene. Two candidate genes were excluded, one by locus refinement and one by sequence analysis. Bulk DNA sequence analyses were performed on the DNAs of five affecteds and one unaffected for all exons for all genes, hypothetical genes, and ESTs within the locus. We also sequenced the proximal 5[prime] region from several of these genes. This resulted in the generation of 3.6 million base pairs of sequence from which we identified 163 novel SNPs and INDELS (insertions/deletions). Interfamilial-genic-consistency and phasing studies ruled out all of these mutations as being causative. A subset of these SNPs was used for a pair of association studies in which we: (1) examined a series of cases and controls; and (2) performed transmission disequilibrium testing. Data from these studies pointed to two possible areas within the GERD I locus, however, at the resolution at which we performed the scan it is likely that the critical region was missed. A plan is presented for future studies in which a high density SNP scan would be performed across the entire locus to identify the causative gene using Illumina's SNP technology and the preliminary human HapMap data.
Regulation of axon collateral branch morphogenesis by septin GTPases
Authors:   , Hu Jianli , Spiliotis Elias T , Gallo Gianluca
Published: March 2023

Development of a functional nervous system requires the formation of correct innervation patterns, which are largely shaped by the axon collateral branching. Axon collateral branches are formed from actin-rich protrusions termed filopodia. Maturation of axon collateral branches requires the unbundling, fragmentation and entry of axonal microtubules into filopodia. During this process, the actin and microtubule cytoskeleton undergo dramatic remodeling and require coordination between actin and microtubules. However, the mechanisms involved remain elusive. Septin GTPases are a family of multifunctional proteins that associate with actin, microtubules and cell membranes. In this thesis, I show that septin 6 (SEPT6) and 7 (SEPT7) are essential for axon collateral branching. In embryonic sensory neurons (chicken dorsal root ganglia), SEPT6 localizes to axonal F-actin patches that serve as precursors to filopodia. In contrast, SEPT7 localizes to the base of axonal shaft filopodia. Both SEPT6 and SEPT7 accumulate at sites of incipient filopodia, but only SEPT6 affects the rate of filopodia formation. Quantitative analysis of actin dynamics revealed that SEPT6 increases the frequency with which filopodia emerge from F-actin patches, but does not affect the formation of F-actin patches and their lifespan. Although SEPT7 has no role in the protrusive activity of F-actin patches, it is essential for microtubule presence in nascent filopodia. Absence of the microtubule-bundling and stabilizing protein MAP1 B from SEPT7 sites and the splaying of microtubules in SEPT7 over-expressing axons indicate that SEPT7 might mediate the unbundling and targeting of microtubules into the nascent filopodia and thus, their maturation to axon collateral branches. Based on these data, I propose a two-step mechanism for the morphogenesis of axon collateral branches. First, SEPT6 triggers the conversion of F-actin patches to axonal filopodia, and second, SEPT7 facilitates the entry of axonal microtubules into the nascent filopodia, and thus the maturation of axon collateral branches. Because septin stabilization with the small molecule compound forchlorfenuron (FCF) triggers the proliferation of axon collateral branches, septins might be an ideal therapeutic target for the regeneration of neuronal branches after spinal cord injury.
Cognitive Abilities Related to Reading and Writing Skills in Chinese Third-grade Children
Authors: Ou Jieping , Sambai Ami , Pei Hong , Uno Akira , Yoneda Hiroki
Published: March 2023

In this study, we analysed the cognitive abilities that predict reading and writing attainment in the Chinese language for Mandarin-speaking children. A total of 140 Chinese third-graders studying in Ningbo, Zhejiang were evaluated for their visual cognition including visual perception and memory, naming speed, vocabulary knowledge, phonological skills, nonverbal intelligence, and abilities to read and write. The results of multiple regression analyses revealed that word and nonword reading accuracy were predicted to a significant degree by visual memory and phonological awareness, respectively. Naming speed significantly contributed to the reading speeds regarding words, nonwords, and paragraphs. Our results also showed that the scores in word and nonword reading predicted the scores of writing as well. Visual memory and phonological awareness are essential for reading Chinese accurately, while naming speed is an important factor for Chinese reading fluency. The present results have implications regarding the design of useful tasks that screen poor readers of Chinese.
The perception of special education teachers towards the involvement of audiologist in special education school
Authors: Yasin Mohd Hanafi Mohd , Tahar Mohd Mokhtar , Mohamad Suziyani , Rasilah Nurul Ezza Aleyza Binti , Azirun Rabaishah
Published: March 2023

Audiologists is an individual that has close connection with deaf and hearing impairment students. This research is done to study the perception of the special education teachers on the involvement of audiologists in special education school. In this research, quantitative data which is questionnaire is used as the research instrument. The data obtained were analyzed using Microsoft Excel XLstat. The total of 165 teachers that are included in this research through snow-balling sampling. Results shown that 149 (90.8 percent) of the teachers agreed that the role of audiologists is vital to improve the special education quality in Malaysia. In general, the teachers have high comprehency toward the common function of the audiologists but a very worrying understanding on their specific role. It is proven when special education teachers are unsure about whether audiologists only work in hospitals (56 teachers (33.9 percent)), involved in balance problems (65 teachers (39.4 percent)) and vestibular problems (88 teachers (53.3 percent)). The research shown that having an audiologist helps to reduce the impact of hearing loss for the deaf students when 152 (83.8 percent) special education teachers agreed that the involvement of audiologists in the education system benefits many teachers and students thus prepares a better and more condusive environment for them.
Key-Specific Structure in Mozart's Music: A Peek into his Creative Process?
Authors: Rom Uri B. , Rosset Saharon
Published: March 2023

Theories of tonal music take for granted that all keys of the same mode (i.e., all major and all minor keys) are employed by composers in essentially the same way; however, newer analytical and cognitive research challenges this view by pointing to aspects of transpositional nonequivalence among the keys. The present study offers possibly the first systematic, data-driven investigation of correlations between the choice of absolute key and structure across a composer's body of works. By performing an extensive corpus-based analysis of music by Wolfgang Amadé Mozart (1756–91), we derive 55 prototypes, subsuming phenomena from three independent domains: dynamic-rhetoric gestures that launch orchestral works, digressions to the parallel minor in sonata-allegro movements, and the occurrences of a particular six-note motive across Mozart's complete oeuvre. Ten prototypes display a significant association with a specific key after correction for multiple comparisons, amounting to a statistically significant total. Investigation of key-related musical structure offers fresh insight into Mozart's compositional decisions and the relation between schemata and their instantiations in his works, at the same time suggesting a revised perspective on traditional key characteristics. Mozart's perfect pitch offers one possible explanation for the role of key-related structure in his works; however, we also contemplate other possible explanations.
Commentary on "A Computational Approach to the Detection and Prediction of (Ir)Regularity in Children's Folk Songs"
Authors: Cancino-Chacon Carlos Eduardo
Published: March 2023

This commentary on "A Computational Approach to the Detection and Prediction of (Ir)Regularity in Children's Folk Songs" by Mihelač, Povoh, and Wiggins reflects on the use of methods of (statistical) expectation to analyze musical structure and regularity, including potential biases of such methods, and provides some perspectives on leveraging information theoretic models of musical expectation to design cognitively plausible computational listeners of music.
Left bundle branch block – dilated cardiomyopathy – heart failure: common links in the closed pathogenetic chain
Authors: Rimskaya E. M. , Mironova N. A. , Sokolov S. F. , Golitsyn S. P.
Published: March 2023

This review summarizes the available information on the epidemiology and prognosis of patients with left bundle branch block (LBBB), morphological alterations of the myocardium both resulting in and ensuing LBBB, cardiac biomechanics in LBBB, and possibilities of its correction.
The role of growth differentiation factor-15 in assessing the prognosis of patients after uncomplicated myocardial infarction
Authors: Galyavich A. S. , Sabirzyanova A. A. , Baleeva L. V. , Galeeva Z. M.
Published: March 2023

Aim    To study the role of growth differentiation factor 15 (GDF-15) in the long-term prognosis for patients after uncomplicated myocardial infarction (MI).Material and methods    This study included 118 MI patients aged <70 years with and without ST-segment elevation on electrocardiogram (ECG). All patients underwent an examination that included ECG, echocardiography, Holter ECG monitoring, routine laboratory tests, and tests for plasma N-terminal pro-brain natriuretic peptide (NT-proBNT) and GDF-15. GDF-15 was measured by ELISA. The dynamics of patients was evaluated by interviews at 1, 3, 6, and 12 months. The endpoints were cardiovascular death and hospitalization for recurrent MI and/or unstable angina. Results    Median concentration of GDF-15 in MI patients was 2.07 (1.55; 2.73) ng/ml. No significant dependence was found between GDF-15 concentration and age and gender, MI localization, smoking, body weight index, total cholesterol, and low-density lipoprotein cholesterol. During 12-month follow-up, 22.8 % of patients were hospitalized for unstable angina or recurrent MI. In 89.6 % of all cases of recurrent events, GDF-15 was ≥2.07 ng/ml. For patients with GDF-15 in the upper quartile, the time dependence of recurrent MI was logarithmic. High concentrations of NT-proBNP in MI patients were also associated with increased risk of cardiovascular death and recurrent cardiovascular events [RR, 3.3 (95 % CI, 1.87–5.96), р=0.046].Conclusion    A combination of GDF-15 and NT-proBNP at high concentrations significantly reflects an adverse prognosis for patients with uncomplicated MI within 12 months [RR, 5.4 (95 % CI, 3.4–8.5), р=0.004].
La resolución alternativa de conflictos en el sector de los derechos de los pasajeros aéreos
Authors: Agüero Ortíz Alicia
Published: March 2023

Tras casi cinco años de espera, el pasado 17 de marzo de 2022 se publicó la Orden TMA/201/2022 por la que se aprueba el procedimiento de resolución alternativa de conflictos derivados de la vulneración de los Reglamentos de la Unión Europea en materia de protección de los usuarios del transporte aéreo del Ministerio de Transportes, Movilidad y Agenda Urbana. En este trabajo analizaremos los aspectos más relevantes del nuevo procedimiento cuya gestión asumirá la AESA, los procedimientos de ADR alternativos existentes, así como aquellos disponibles para reclamaciones no incluidas en el ámbito de aplicación de este procedimiento. Asimismo, compararemos el nuevo procedimiento con los existentes en otros Estados miembros.
La doctrina del TJUE sobre el inicio del plazo de prescripción de la acción de restitución de los gastos hipotecarios: influencia del derecho alemán y efectos en el derecho español
Authors: Marin López Manuel Jesús
Published: March 2023

El TJUE ha dictado cuatro sentencias sobre el inicio del plazo de prescripción de la acción de restitución de cantidades derivado de la nulidad de una cláusula abusiva (SSTJUE de 9 de julio de 2020, 16 de julio de 2020, 22 de abril de 2021 y 10 de junio de 2021). Pero pronto tendrá que pronunciarse de nuevo sobre el particular, cuando tenga que resolver las tres cuestiones prejudiciales planteadas, en relación con la restitución de los gastos hipotecarios, por el Tribunal Supremo, la AP de Barcelona y el JPI nº 20 de Barcelona. Este trabajo analiza con detalle la doctrina del TJUE sobre el dies a quo de la acción de restitución, la influencia que en la misma ha tenido la jurisprudencia alemana, la respuesta que el TJUE dará a las preguntas formuladas en las tres cuestiones prejudiciales, y el modo en que esta doctrina del TJUE ha de afectar al derecho español.
Comentario a la nueva STS (367/2022 de 4 de mayo) en materia de créditos revolving ¿Ha habido cambio de doctrina?
Authors: Reinhart Schuller Robert
Published: March 2023

La nueva sentencia del TS en materia de créditos revolving ha dado pie a múltiples interpretaciones. Las diferencias interpretativas sobre esta sentencia han sido tan relevantes, que el TS ha tenido que hacer uso de una nota informativa para aclarar el asunto. En este comentario, se analizará el caso concreto, así como también se intentará poner de relieve los puntos más controvertidos del caso. De este modo, se pretende aclarar el status quo de los créditos revolving tras la nueva STS.
Relationship between the Position of the Mandibular Third Molar with Different Vertical Skeletal Dimensions on the Panoramic Images in Patients Referred to Isfahan (Khorasgan) University Dental School
Authors: Eskandari Fatemeh , Esnaashari Nasim , Ghaffari Roshanak , Mousavizadeh Mobarakeh Seyedeh Leila
Published: March 2023

Introduction: Due to the increased prevalence of third molar impaction and the complications and existence of disagreements regarding the predicting factors for the impaction of this tooth, the aim of this study was to evaluate the relationship between the position of the mandibular third molar with different vertical skeletal dimensions on the panoramic images.Materials & Methods: This cross sectional study was carried out on lateral cephalogram and orthopantomogram records of 130 orthodontic patients visiting to Isfahan (Khorasgan) University Dental School. Age range of the sample was 20-35 years. Various facial forms were determined with mandibular plane angle (SN-GoGn), jarabak index and Y-axis; S-GN– Frankfort plane. Beta angle; which is the angle between intersecting long axis of mandibular second molar and mandibular third molar was measured to determine the angle of eruption of mandibular third molar. Eruption pattern was classified as per Pell & Gregory and winter’s system. The data were analyzed by Chi-square test (p value < 0.05).Results: There was a significant difference in the frequency distribution of growth pattern on the left side of the jaw (p value = 0.048). There was no significant difference in the frequency distribution of the eruption pattern in the right side of the jaw (p value = 0.11). There was no significant difference in the frequency distribution of eruption surface in the right face between different facial forms (p value = 0.49) But on the left side of the jaw there was a significant difference between the three facial forms (p value = 0.049). Frequency distribution of mandibular third molar impaction was significantly different between the three facial forms (p value = 0.03). There was no significant difference between the three facial forms in terms of frequency of eruption angle in the right side of the jaw (p value = 0.25) and also in the left side of the jaw (p value = 0.15).Conclusion: The incidence of impaction was significantly more in patients with long face than in other two groups. The prevalence of surface and pattern of third molar eruption in only one side of jaw was significantly different between the three facial forms. There was no significant difference between the frequency of angle of eruption and facial skeletal types in both jaws.
Effects of Oral Liquid Medicaments in Children on Shear Bond Strength of Resin Composite in Primary Teeth
Authors: Fotoohi Ashin Sara , Toodeshkchooie Davoud Ghasemi , Barekatain Mehrdad
Published: March 2023

Introduction: Due to the prevalence of the use of oral liquid medications in children with chronic diseases (asthma, heart problems, seizures and kidney problems) and also in children with transient diseases (influenza, colds, tonsillitis, ear infections, sinusitis and seasonal allergy) and due to the fact that several studies have shown that children’s' common medications affect topography and enamel structure, and composite bonding is dependent on enamel structure, the aim of this study was to investigate the effect of oral liquid medications used in children on composite bond strength to primary canine dental enamel.Materials & Methods: In this experimental-laboratory study, 90 teeth were divided into 9 groups, 8 drug groups and 1 control group (artificial saliva). Each group of 10 teeth was immersed 3 times a day for 1 minute in 10 ml of the desired drug. After 7 days and after 14 days, 5 teeth from each group were bonded with composite and their shear bond strengths were measured. Data were analyzed by one-way ANOVA, paired T-test and Pearson correlation coefficient tests. (α = 0.05).Results: In all groups, in comparison with the control group, the mean bond strength was not significantly different in the first and second weeks (p value > 0.05). Also, there was no significant difference between the mean composite shear bond strengths in each of the nine groups in the first and second weeks (p value > 0.05). Pearson correlation coefficient showed that there was no significant relationship between PH value with shear bond strength of composite in first weeks (p value = 0.53) and second (p value = 0.83).Conclusion: Based on this study, short-term use (up to 14 days) of medications did not significantly change the shear bond strength of the composite to enamel.
Evaluation of Oral Health- Related Quality of Life after Implant Treatment versus Root Canal Treatment
Authors: Momeni Golnoush , Rafiei Ehsan , Ranjbarian Parisa , Babaei Sajad
Published: March 2023

Introduction: Preserving the natural tooth by endodontic treatment or tooth extraction and implantation is an important dilemma that requires careful evaluation of the factors that affect the final treatment and patients' quality of life. The aim of this study was to evaluate the quality of life related to oral health after single tooth implant treatment in comparison with endodontic treatment.Materials & Methods: This study is a cross-sectional analytical study to evaluate the quality of life of 80 patients referred to Isfahan Azad Dental School in 1399-1400 in two groups (endo and implant) whose anterior teeth have been endodontically treated and had also a history of anterior single tooth implant with functional crown in a recent year, with using Oral health-related quality of life questionnaire (OHIP-12). The collected data were analyzed using Shapiro-Wilk test and independent T-test with an error level of 0.05% (p value < 0.05).Results: Mean patient's oral health-related quality of life after single tooth implant and after endodontic treatment was respectively 16.95 and 16.83 and all the studied parameters were shown to be above average. There was no significant difference between the type of treatment and patient's oral health-related quality of life (p value = 0.885). There was a significant difference between patient's gender and oral health-related quality of life in implant treatment (p value = 0.036).Conclusion: The oral health-related quality of life after single tooth implant treatment was comparable to endodontic treatment in patients and it was higher than average in both treatments.
Immunohistochemical Expression of Alpha Smooth Muscle Actin Positive Myofibroblast and Laminin 5 gamma 2 in Squamous Cell Carcinoma and Verrucous Carcinoma of the Oral Cavity
Authors: Mardani Homeyra , Rashnavadi Bahareh , Moghadam Noshin Afshar
Published: March 2023

Introduction: Squamous cell carcinoma is the most common type of oral cancer that shows certain tissue changes. Laminin-5γ2 is a protein that plays a central role in migration of the neoplastic cells during tumor invasion. Expression of this protein in cells and stroma adjacent to tumor can confirm the cellular invasion. The aim of this study was to evaluate stroma in verrucous carcinoma and squamous cell carcinoma of the mouth using two markers α SMA and laminin 5 gamma 2.Materials & Methods: In this retrospective descriptive-analytical study, 60 samples were selected with the diagnosis of squamous cell carcinoma and verrucous oral carcinoma. Then, two markers of α SMA and laminin 5 gamma 2 were examined in epithelium and mesenchymal stroma by immunohistochemistry. The vasculature was used as a positive immunoreactivity control for alpha-smooth muscle and the normal mucosa was used to control the positive immunoreactivity of laminin 5 gamma 2. The results were analyzed using Chi-square and Spearman correlation tests (α = 0.05).Results: Out of 31 SCC samples, 80.6% showed laminin 5 gamma 2 and 90.3% showed alpha smooth and out of 9 samples of varocus carcinoma, 66.7% showed laminin 5 gamma 2 and 77.8% showed alpha smooth actin. The higher the positive percentage of laminin, the higher the percentage of positive α SMA.Conclusion: Expression of alpha smooth muscle actin and lamminin 5 gamma 2 was significantly higher in oral squamous cell carcinoma and there exists a correlation between expression of alpha smooth muscle actin and the increase in myofibroblasts takes place during the carcinogenesis process.