bluuebunny/crossref_metadata_2025 huggingface dataset:
Signs of anomalous behavior of the ionosphere in 2003–2014 at F1-layer heights over Irkutsk
Authors: Kushnarenko Galina , Yakovleva Olga , Kuznetsova Galina
Published: June 2021

We have detected an anomalous electron density Ne increase in winter months in Irkutsk in some years of the period 2003–2014. This effect was manifested when we compared the experimental values obtained by the Irkutsk ionosonde with model calculations at F1-layer heights (120–200 km). Two anomalous time zones have been found. The first was observed in the period 2003–2006 near solar minimum. In this zone, 2003 is the year of maximum manifestation of the winter Ne increase over the entire research period. The second anomalous zone — 2012, 2013, 2014 — was detected during solar maximum. We have explored possible causes of the Ne change in winter at the F1-layer heights in all the years under study. We have found that the main factor causing the winter increase in Ne is significant geomagnetic disturbances in the above time periods.
Hidden Music in Early Elizabethan Tragedy
Authors: Duffin Ross W.
Published: June 2021

In modern times, scholars have widely regarded early Elizabethan tragedy, like Thomas Norton and Thomas Sackville’s Gorboduc (1561/62) and its successors at the Inns of Court, as verbose and unlyrical. Those criticisms may reflect an incomplete understanding of the original performance tradition, however. Like Senecan tragedies from this period, those plays include act-ending choruses, mostly in pentameter and in various stanza configurations. This study proposes that in the English tragedies, at least, those choruses were very likely sung, most probably to tunes from the emerging repertoire of metrical psalms. These findings would significantly affect the character of such plays and how they are perceived by scholars and audiences alike.
‘Et dat alapam vita’: A Stage Direction in the Chester 'Noah’s Flood'
Authors: Whiteford Peter
Published: June 2021

This note considers the role of one of the stage directions in the Chester cycle. The direction ‘et dat alapam vita’, found only in British Library MS Harley 2124, records the blow struck by Noah’s wife after her sons force her aboard the ark, and is typically discussed in the context of the misogynistic ‘humour’ found in other dramatic and non-dramatic texts of the period. In this note, I provide an alternative, typological reading of the stage direction.
Yasmin Arshad. Imagining Cleopatra: Performing Gender and Power in Early Modern England. London: Bloomsbury, 2019. Pp 337.
Authors: León Alfar Cristina
Published: June 2021

Review of Yasmin Arshad's Imagining Cleopatra: Performing Gender and Power in Early Modern England by Cristina León Alfar.
David Gunby, David Carnegie, and MacDonald P. Jackson, eds. The Works of John Webster, Vol. IV. Cambridge: Cambridge University Press, 2019. Pp 642.
Authors: Pérez Díez José
Published: June 2021

José A. Pérez Díez's review of The Works of John Webster, Vol. IV, edited by David Gunby, David Carnegie, and MacDonald P. Jackson.
Kirk Melnikoff and Roslyn Knutson eds. Christopher Marlowe, Theatrical Commerce, and the Book Trade. Cambridge: Cambridge University Press, 2018. Pp 313.
Authors: Maguire Laurie
Published: June 2021

Laurie Maguire's Review of Christopher Marlowe, Theatrical Commerce, and the Book Trade, edited by Kirk Melnikoff and Roslyn Knutson.
Andrew Bozio, Thinking Through Place on the Early Modern English Stage. Oxford: Oxford University Press, 2020. Pp 240.
Authors: Martin Randall
Published: June 2021

Review of Andrew Bozio's Thinking Through Place on the Early Modern English Stage by Randall Martin.
Lucy Munro. Shakespeare in the Theatre: The King’s Men. London: Bloomsbury, 2020. Pp 239.
Authors: Price Eoin
Published: June 2021

Review of Lucy Munro's Shakespeare in the Theatre: The King’s Men by Eoin Price.
LA RESPUESTA DEL SISTEMA PRESTACIONAL FRENTE AL RETO COVID-19.
Authors: Diaz Mordillo Maria Alexandra
Published: June 2021

Desde que en enero de 2020 se identificara un nuevo tipo de coronavirus denominado SARS-CoV-2, una serie de acontecimientos relacionados con la salud pública han marcado profundamente los principios de la realidad sanitaria, social, económica y jurídica a nivel mundial. Las medidas adoptadas en nuestro país para paliar los efectos de la pandemia han ocasionado un elevado coste económico y social. Estas medidas se han articulado jurídicamente en torno a la declaración del estado de alarma y a la publicación de una serie de Reales Decretos-leyes dirigidos a minimizar las consecuencias socioeconómicas de la pandemia. En materia de Seguridad Social, se ha utilizado la adaptación reglamentaria prevista en el artículo 42 del TRLGSS para acompasar el sistema de protección a una realidad marcada por el nuevo agente infeccioso. La prestación de incapacidad temporal se utiliza como instrumento de salud pública para hacer frente a estas nuevas situaciones, modificando la contingencia según el devenir temporal y la adaptación a las necesidades de determinados colectivos, sobre todo sanitarios y socio-sanitarios, por su alto nivel de incidencia. Mediante este estudio se sistematiza la normativa publicada hasta la fecha, ahondando en el momento temporal y la situación de necesidad protegible.
IMPACTOS DE LA COVID-19: LA BUSCA POR LA IGUALTAD DE GÉNERO COMO FACTOR NECESARIO PARA EL DESARROLLO SOSTENIBLE.
Authors: Christina Nahas Thereza
Published: June 2021

La pandemia acentuó las disparidades de género. La discriminación por razón de género y la desigualdad se profundizaron con las restricciones y medidas de aislamiento social adoptadas por los diversos países, en todo el mundo, para intentar contener la expansión del contagio durante la pandemia de la COVID-19. Las brechas salariales y la desigualdad son una realidad globalizada, pero presentan índices distintos dependiendo del desarrollo económico social y cultural de cada país. Resulta necesario empoderar a las mujeres para extirpar la desigualdad, factor que permitirá el mayor crecimiento económico y un desarrollo social sostenible. La lucha por la igualdad de género se encuentra orientada por los organismos internacionales de naturaleza económica y social. Es preciso dar voz a las mujeres y acabar con el estigma que las aboca a someterse a las formas violentas de opresión moral y física. América Latina y Caribe son tradicionalmente regiones con los más altos índices de violencia contra la mujer. De persistir esta situación, en un momento en el que el movimiento global reclama unión y cooperación de todas las naciones, podrá conllevar un retroceso social para todas las naciones.
CRITICITÀ DELLA NORMATIVA IN TEMA DI ASSISTENZA SOCIALE PER GLI EXTRACOMUNITARI IN ITALIA.
Authors: Loria Salvatore
Published: June 2021

Attraverso l’esame della normativa, italiana e comunitaria, nonché delle pronunce giurisprudenziali delle diverse Corti, si tenta di individuare –anche se non in maniera esaustiva e definitiva– le criticità della stessa normativa in tema di assistenza sociale per gli extracomunitari presenti nel territorio italiano e proporre riforme che siano effettivamente in grado di incidere strutturalmente sull’attuale sistema di protezione sociale che attualmente esclude una parte della popolazione e, nello specifico, la popolazione straniera povera.
Personal data in artificial intelligence projects: main study elements.
Authors: Rodríguez Ayuso Juan Francisco
Published: June 2021

This research focuses on the impact of the new regulations on the protection of personal data in the scientific field of computer science, which is centered on the creation of programs and mechanisms that can display behaviors considered intelligent. In other words, the necessary respect for the fundamental right to data protection in those technological advances that, progressively, make machines think like human beings, determining what are the possible legal bases that can be found to legitimize all processing of personal data that occur in this new field.
Política, Poder y Género en las series de televisión europea Borgen (Dinamarca) y Le Baron Noir (Francia).
Authors: Cunha Isabel
Published: June 2021

Nesta exposição, analisa-se como a Política, o Poder e o Género são representados nas séries televisivas europeias Borgen (Dianamarca) e Le Baron Noir (França). Borgen foi exibida entre 2010 e 2013 e tem como protagonista principal, Birgitte Nyborg, uma candidata de um pequeno partido político que se torna, mais tarde, primeira-ministra dinamarquesa. Le Baron Noir é uma série francesa (2016- 2020) que tem como protagonistas principais Philipe Rickwaert e Amélie Dorendeu, militantes destacados do partido socialista francês e candaditos à presidência. As duas obras de fição focam a mediatização e a profissionalização da política; a complexidade da tomada de decisões; as contradições entre a realpolitik e a moral, bem como os desafios pessoais que se colocam aos atores políticos, nomeadamente às mulheres. O objetivo do artigo é identificar semelhanças e diferenças entre as duas séries nos aspetos ficcional, polítíco e na abordagem do exercício do poder em função do género. Com vista a contextualizar a análise, o estudo traça um breve histórico das obras de ficção televisiva exibidas em Portugal, com ênfase na política e nas questões de género. A metodologia utilizada é ensaística e fundamenta-se na análise das personagens e trajetórias das protagonistas femininas, a partir de categorias pré-definidas, com base em princípios da teoria da narratologia
La traducción como problema en la prensa virreinal. El caso del Semanario de Agricultura, Industria y Comercio (1802-1807).
Authors: Maggio Ramírez Matías
Published: June 2021

El análisis de las fuentes de información del Semanario de Agricultura, Industria y Comercio, que se publicó en Buenos Aires entre 1802 y 1807, permitió cuestionar la historiografía tradicional que le atribuyó a Juan Hipólito Vieytes, editor del periódico, el rol de traductor. El análisis comparativo de las fuentes demostró que las traducciones francesas que se reprodujeron en el periódico no se realizaron en Buenos Aires, sino que tenía como origen Madrid. La atribución de las traducciones puso en valor a los periódicos españoles de finales del siglo XVIII y principios del siglo XIX, para los lectores americanos, y permitió relacionar la prensa virreinal bonaerense con la práctica de lectura de los libros de lugares comunes.
Efficient Estimation of Network Games of Incomplete Information: Application to Large Online Social Networks
Authors: Chen Xi , van der Lans Ralf , Trusov Michael
Published: June 2021

This paper presents a structural discrete choice model with social influence for large-scale social networks. The model is based on an incomplete information game and permits individual-specific parameters of consumers. It is challenging to apply this type of models to real-life scenarios for two reasons: (1) The computation of the Bayesian–Nash equilibrium is highly demanding; and (2) the identification of social influence requires the use of excluded variables that are oftentimes unavailable. To address these challenges, we derive the unique equilibrium conditions of the game, which allow us to employ a stochastic Bayesian estimation procedure that is scalable to large social networks. To facilitate the identification, we utilize community-detection algorithms to divide the network into different groups that, in turn, can be used to construct excluded variables. We validate the proposed structural model with the login decisions of more than 25,000 users of an online social game. Importantly, this data set also contains promotions that were exogenously determined and targeted to only a subgroup of consumers. This information allows us to perform exogeneity tests to validate our identification strategy using community-detection algorithms. Finally, we demonstrate the managerial usefulness of the proposed methodology for improving the strategies of targeting influential consumers in large social networks.

This paper was accepted by Matthew Shum, marketing.
The problem with the UK's sweet tooth
Authors: O'Neill Maxwell
Published: June 2021

Maxwell O'Neill explores the value of a balanced diet
Supporting oral health through pregnancy
Authors: Reeves Juliette
Published: June 2021

Juliette Reeves explains the importance of periodontal health throughout pregnancy
Managing paediatric dental anxiety
Authors: Pahal Sabrina
Published: June 2021

Sabrina Pahal explores the role of dental nurses in delivery of inhalation sedation to paediatric patients
Embracing opportunities
Authors: Hylton Preetee
Published: June 2021

Preetee Hylton talks to Kirsty Herridge about her career
How to improve diversity in patient and public involvement
Authors: Golenya Rebecca , Chloros George D , Panteli Michalis , Giannoudis Peter V , Howard Anthony
Published: June 2021

Patient and public involvement involves ascertaining the opinions of and collaborating with patients and members of the public to holistically improve the quality of research. Patient and public involvement provides patients with a platform to use and share their lived experiences. This allows healthcare professionals to gain a deeper appreciation of the patient's perspective, which enables future research to be more patient centred and tailored to patients' requirements.

Patient and public involvement aims to broadly encapsulate the opinions of the public, so ensuring diversity is recommended. This article provides a practical framework to increase diversity and engage hard-to-reach demographics in patient and public involvement. It highlights some common barriers to participation and methods for overcoming this, describes sampling frameworks and provides examples of how these have been adopted in practice.
Ethical challenges faced when there is a mismatch between guidelines, patient autonomy and clinical practice
Authors: Hughes John , de Gray Lorraine
Published: June 2021

This editorial reviews the ethical day-to-day challenges faced by pain specialists when managing each patient's unique requirements, in light of guidelines, clinical practice and interpretation of evidence relating to the assessment and management of chronic pain.
Clinical evaluation after matrix-associated autologous chondrocyte transplantation
Authors: Binder Harald , Hoffman Lukas , Zak Lukas , Tiefenboeck Thomas , Aldrian Silke , Albrecht Christian
Published: June 2021

Aims

The aim of this retrospective study was to determine if there are differences in short-term clinical outcomes among four different types of matrix-associated autologous chondrocyte transplantation (MACT).

Methods

A total of 88 patients (mean age 34 years (SD 10.03), mean BMI 25 kg/m2(SD 3.51)) with full-thickness chondral lesions of the tibiofemoral joint who underwent MACT were included in this study. Clinical examinations were performed preoperatively and 24 months after transplantation. Clinical outcomes were evaluated using the International Knee Documentation Committee (IKDC) Subjective Knee Form, the Brittberg score, the Tegner Activity Scale, and the visual analogue scale (VAS) for pain. The Kruskal-Wallis test by ranks was used to compare the clinical scores of the different transplant types.

Results

The mean defect size of the tibiofemoral joint compartment was 4.28 cm2(SD 1.70). In total, 11 patients (12.6%) underwent transplantation with Chondro-Gide (matrix-associated autologous chondrocyte implantation (MACI)), 40 patients (46.0%) with Hyalograft C (HYAFF), 21 patients (24.1%) with Cartilage Regeneration System (CaReS), and 15 patients (17.2%) with NOVOCART 3D. The mean IKDC Subjective Knee Form score improved from 35.71 (SD 6.44) preoperatively to 75.26 (SD 18.36) after 24 months postoperatively in the Hyalograft group, from 35.94 (SD 10.29) to 71.57 (SD 16.31) in the Chondro-Gide (MACI) group, from 37.06 (SD 5.42) to 71.49 (SD 6.76) in the NOVOCART 3D group, and from 45.05 (SD 15.83) to 70.33 (SD 19.65) in the CaReS group. Similar improvements were observed in the VAS and Brittberg scores.

Conclusion

Two years postoperatively, there were no significant differences in terms of outcomes. Our data demonstrated that MACT, regardless of the implants used, resulted in good clinical improvement two years after transplantation for localized tibiofemoral defects. Cite this article: Bone Joint Res 2021;10(7):370–379.
The Colorectal Telephone Clinic: a new normal post-COVID-19?
Authors: Sagar A , Mai DVC , Rumy N , Al-Habsi R , Divya GS , Singh A
Published: June 2021

Introduction

In light of the COVID-19 recommendations from the Association of Coloproctology of Great Britain and Ireland, we aimed to study patient and clinician satisfaction with a newly established telephone (TP) colorectal clinic service in lieu of traditional face-to-face (FTF) appointments. Comparative outcomes included patient versus clinician satisfaction; patient versus clinician desire to continue TP clinics postpandemic; and views of Specialty Trainee 3+ (ST3+)/Specialty Associate Specialist (SAS) doctors versus consultants on TP compared with FTF appointments.

Methods

We conducted a prospective service evaluation of patient and clinician satisfaction with colorectal surgery TP clinics between 1 June 2020 and 30 June 2020 in a British District General Hospital.

Results

Patients had higher satisfaction than clinicians with TP clinics: 91.5% versus 66.6% reported above-average experience [odds ratio (OR) = 5.35, 95% confidence interval (CI) 1.53 to 18.75, p = 0.01]. Clinicians had lower demand to continue TP clinics post-COVID-19 versus patients, with a trend towards significance (60% versus 82.9%, OR = 0.31, 95% CI 0.10 to 0.97, p = 0.08). ST3+/SAS doctors were more likely than consultants to find TP clinics inferior to FTF consultation for patient assessment (48.3% versus 23.7%, OR = 3.00, 95% CI 1.17 to 7.71, p = 0.03).

Conclusions

While clinicians may be concerned that patient assessment suffers, patient satisfaction with TP clinics is high. There should be a place for TP clinics post-COVID-19 but there must be a robust process for patient selection as well as adequate training for current and future generations of clinicians.
Variations in origin of the superior thyroid artery: an update for the head and neck surgeon
Authors: Shaw S , Maharaj K , Mirza T
Published: June 2021

Head and neck surgeons must have a thorough knowledge of head and neck vascular anatomy and its variations. This case report documents a variation in the superior thyroid artery encountered during a neck dissection and discusses the surrounding literature. A 55-year-old female with squamous cell carcinoma of the tongue underwent a partial glossectomy, right level I–IV neck dissection and reconstruction with a radial forearm free flap. During the procedure, an arterial branch was encountered arising 2–3cm caudal to the common carotid bifurcation. This variant branch was shown to represent the superior thyroid artery. On review of the literature, various classification systems of the superior thyroid artery origin have been described. Awareness of such anatomical variation is vital for the head and neck surgeon to avoid unexpected complication.
Graphene-supported tunable bidirectional terahertz metamaterials absorbers
Authors: Peng Jun , Leng Jin , Cao Duo , He Xiaoyong , Lin Fangting , Liu Feng
Published: June 2021

Based on asymmetric graphene ellipses, the tunable propagation characteristics of metamaterial absorber (MMA) have been investigated in the THz region. Two distinct absorption peaks of 84% and 90% are observed at 1.06 THz and 1.67 THz, respectively. Besides a high Q factor exceeding 20, the Fano resonance can also be modulated in a wide range (e.g., the frequency modulation depth reaches more than 43.8% if the Fermi energy level changes in the range of 0.2–1.0 eV). Additionally, a bidirectional THz MMA is achieved by replacing the metal substrate with a uniform graphene layer. If the terahertz wave is incident in the forward direction, the proposed graphene double stripe microstructure shows a typical MMA with its absorption reaching 88%. On the other hand, if the terahertz wave is incident in the reverse direction, the graphene double stripe microstructure behaves as a reflective modulator, and its amplitude and frequency MD will reach 60% and 85%. These results contribute to the design of tunable THz devices, such as filters, absorbers, and modulators.
Mueller matrix polarimetry and polar decomposition of articular cartilage imaged in reflectance
Authors: Huynh Ruby N. , Nehmetallah George , Raub Christopher B.
Published: June 2021

Articular cartilage birefringence relates to zonal architecture primarily of type II collagen, which has been assessed extensively in transmission, through thin tissue sections, to evaluate cartilage repair and degeneration. Mueller matrix imaging of articular cartilage in reflection is of potential utility for non-destructive imaging in clinical and research applications. Therefore, such an imaging system was constructed to measure laser reflectance signals, calibrated, and tested with optical standards. Polar decomposition was chosen as a method to extract fundamental optical parameters from the experimental Mueller matrices, with performance confirmed by simulations. Adult bovine articular cartilage from the patellofemoral groove was found to have ∼0.93 radians retardance, low diattenuation of ∼0.2, and moderately high depolarization of 0.66. Simulations showed that variation in depolarization drives inaccuracy of depolarization and retardance maps derived by polar decomposition. These results create a basis for further investigation of the clinical utility of polarized signals from knee tissue and suggest potential approaches for improving the accuracy of polar decomposition maps.
Wideband, large mode field and single vector mode transmission in a 37-cell hollow-core photonic bandgap fiber
Authors: You Yong , Guo Huiyi , Hao Yundong , Wang Zhi , Liu Yan-ge
Published: June 2021

Stable generation and propagation of ultrafast high-order mode beams has become an important research direction. A core diameter not more than 10 times the wavelength is regarded as the upper limit for single mode transmission. However, a high-power laser requires a core diameter 20 to 40 times the wavelength to achieve high-power and stable output, which exceeds the design limit of the traditional fiber. In this paper, a novel 37-cell hollow core photonic bandgap fiber (HC-PBF) that only supports pure TE01 mode over a bandwidth of 50 nm with the lowest loss of 0.127 dB/km is proposed. The HC-PBF has a core diameter of more than 40 μm. Single mode guidance is achieved by adjusting the lattice size in a particular of the cladding. The best single mode performance with a loss ratio as high as 150,000 between TE01 mode and other modes with minimum loss is obtained. The fiber also has low bend-loss and thus can be coiled to a small bend radius of 1 cm having 1.6 dB/km bend loss. The tunability of the single-mode window and the manufacturing feasibility of the proposed fiber are also discussed.
Incidence and predictors of mortality among children co-infected with tuberculosis and human immunodeficiency virus at public hospitals in Southern Ethiopia
Authors: Dawit Zinabu , Abebe Sintayehu , Dessu Samuel , Mesele Molalegn , Sahile Serekebirhan , Ajema Desalegn
Published: June 2021

Background

Tuberculosis and human immune deficiency virus co-infections remained the most common cause of child mortality for the last ten years. Globally, 1.2 million cases of tuberculosis occurred in patients living with HIV/AIDS, of which 1.0 million cases occurred in children. The public health impact of tuberculosis and human immune deficiency virus co-infection among children is high in developing countries and Sub-Saharan Africa accompanied three fourth of the global burden. However, there are limited studies that assess the incidence and predictors of mortality among tuberculosis and human immune deficiency virus co-infected children in Ethiopia.

Methods

A facility-based retrospective cohort study was conducted at Public hospitals in Southern Ethiopia with a total of 286 randomly selected records of ART enrolled children from 1st January 2009 to 31stDecember 2018. Data were entered into Epi Data version 3.1 and exported to STATA version 14 for analysis. Bivariate and multivariable Cox proportional hazards model was fitted to identify the predictors of mortality. Variables that had a p-value<0.05 at 95%CI in the multivariable cox proportional hazard model were considered as statistically significant.

Results

A total of 274 tuberculosis and human immunodeficiency virus co-infected children’s records were reviewed. The incidence of mortality among tuberculosis and human immunodeficiency virus co-infected children was 17.15 per 100 children. The overall incidence density rate of mortality was 2.97(95%CI: 2.2, 3.9) per 100 child year of observation and being anemic (AHR: 2.6; 95%CI: 1.28, 5.21), not initiating isoniazid prophylaxis therapy (AHR: 2.8; 95%CI: 1.44, 5.48), developing extrapulmonary tuberculosis (AHR: 5.7; 95%CI: 2.67, 12.56) and non-adherence (AHR: 5.2; 95%CI: 2.19, 12.39) were independent predictors of mortality.

Conclusion

Mortality rate was high among TB/HIV co-infected children at the public hospitals in Southern Ethiopia. Extra-pulmonary tuberculosis, anemia, non-adherence, and isoniazid preventive therapy use were statistically significant predictors of mortality among TB/HIV co-infected children. Therefore, extra pulmonary tuberculosis, and anemia should be closely monitored to increase their adherence as well as they should be provided with isoniazid preventive therapy.
Evaluating the association between COVID-19 and psychiatric presentations, suicidal ideation in an emergency department
Authors: McDowell Michal J. , Fry Carrie E. , Nisavic Mladen , Grossman Mila , Masaki Charles , Sorg Emily , Bird Suzanne , Smith Felicia , Beach Scott R.
Published: June 2021

Objective

To estimate the association between COVID-19 and Emergency Department (ED) psychiatric presentations, including suicidal ideation.

Methods

Using an interrupted time series design, we analyzed psychiatric presentations using electronic health record data in an academic medical center ED between 2018 and 2020. We used regression models to assess the association between the onset of the COVID-19 outbreak and certain psychiatric presentations. The period February 26–March 6, 2020 was used to define patterns in psychiatric presentations before and after the coronavirus outbreak.

Results

We found a 36.2% decrease (unadjusted) in ED psychiatric consults following the coronavirus outbreak, as compared to the previous year. After accounting for underlying trends, our results estimate significant differential change associated with suicidal ideation and substance use disorder (SUD) presentations following the outbreak. Specifically, we noted a significant differential increase in presentations with suicidal ideation six weeks after the outbreak (36.4 percentage points change; 95% CI: 5.3, 67.6). For presentations with SUD, we found a differential increase in the COVID-19 time series relative to the comparison time series at all post-outbreak time points and this differential increase was significant three weeks (32.8 percentage points; 95% CI: 4.0, 61.6) following the outbreak. Our results estimate no differential changes significant at thePvalue < 0.05 level associated with affective disorder or psychotic disorder presentations in the COVID-19 time series relative to the comparator time series.

Conclusions

The COVID-19 outbreak in Boston was associated with significant differential increases in ED presentations with suicidal ideation and SUD.
Temporal determinants of tumour response to neoadjuvant rectal radiotherapy
Authors: Koo Kendrick , Ward Rachel , Smith Ryan L. , Ruben Jeremy , Carne Peter W. G. , Elsaleh Hany
Published: June 2021

Introduction

In locally advanced rectal cancer, longer delay to surgery after neoadjuvant radiotherapy increases the likelihood of histopathological tumour response. Chronomodulated radiotherapy in rectal cancer has recently been reported as a factor increasing tumour response to neoadjuvant treatment in patients having earlier surgery, with patients receiving a larger proportion of afternoon treatments showing improved response. This paper aims to replicate this work by exploring the impact of these two temporal factors, independently and in combination, on histopathological tumour response in rectal cancer patients.

Methods

A retrospective review of all patients with rectal adenocarcinoma who received long course (≥24 fractions) neoadjuvant radiotherapy with or without chemotherapy at a tertiary referral centre was conducted. Delay to surgery and radiotherapy treatment time were correlated to clinicopathologic characteristics with a particular focus on tumour regression grade. A review of the literature and meta-analysis were also conducted to ascertain the impact of time to surgery from preoperative radiotherapy on tumour regression.

Results

From a cohort of 367 patients, 197 patients met the inclusion criteria. Complete pathologic response (AJCC regression grade 0) was seen in 46 (23%) patients with a further 44 patients (22%) having at most small groups of residual cells (AJCC regression grade 1). Median time to surgery was 63 days, and no statistically significant difference was seen in tumour regression between patients having early or late surgery. There was a non-significant trend towards a larger proportion of morning treatments in patients with grade 0 or 1 regression (p = 0.077). There was no difference in tumour regression when composite groups of the two temporal variables were analysed. Visualisation of data from 39 reviewed papers (describing 27379 patients) demonstrated a plateau of response to neoadjuvant radiotherapy after approximately 60 days, and a meta-analysis found improved complete pathologic response in patients having later surgery.

Conclusions

There was no observed benefit of chronomodulated radiotherapy in our cohort of rectal cancer patients. Review of the literature and meta-analysis confirms the benefit of delayed surgery, with a plateau in complete response rates at approximately 60-days between completion of radiotherapy and surgery. In our cohort, time to surgery for the majority of our patients lay along this plateau and this may be a more dominant factor in determining response to neoadjuvant therapy, obscuring any effects of chronomodulation on tumour response. We would recommend surgery be performed between 8 and 11 weeks after completion of neoadjuvant radiotherapy in patients with locally advanced rectal cancer.
Le sultanat d’Oman : un territoire d’exception pour l’étude de la tectonique des plaques et la géomorphologie.
Authors: Salomon Jean-Noël
Published: June 2021

La pointe Nord-est de la plaque arabique et plus précisément le Sultanat d’Oman s’avère être un territoire d’exception pour comprendre les questions géologiques et géomorphologiques qui se posent aux scientifiques. Que ce soient les problèmes de la tectonique des plaques, des orogenèses (lithologie, structure, tectonique) ou des morphologies de surface (érosion fluviale, éolienne, littorale, karstogenèse, etc.) les parcours dans les montagnes d’Oman, ses canyons ou ses déserts se révèlent très instructifs. Parmi les intérêts principaux on soulignera la présence du plus vaste plancher océanique exondé au monde (site de Sémail), l’incision en canyons des terrains soulevés, un important karst méconnu et des déserts exceptionnels. Ces circonstances particulières ont également fait d’Oman un lieu de gisement miniers de métaux rares et hydrocarbures à la base d’une occupation humaine très ancienne et, avec le tourisme, de sa richesse actuelle.
Moderations in performance, immunity, tissue architecture, and vaccine viability induced by water magnetization in broiler farms
Authors: Soliman Essam S. , Hamad Rania T. , Hassan Rania A.
Published: June 2021

Background and Aim: Water magnetization contributes to increased molecular ionization and fluidity, which improves biological activities. This study tests the influence of magnetic water on the viability of the Newcastle vaccine and the survival of Escherichia coli and Salmonella Typhimurium, as well as the influence of magnetic water in face of water impurities' challenges on performance, immunity, and tissue architecture in broiler chickens.

Materials and Methods: An in vitro 96-micro-well plate minimal inhibitory concentration was utilized to test the influence of water, saline, and magnetic water on Newcastle vaccine viability and E. coli O157:H7 and S. Typhimurium survival. The 245 experimental 1-day-old female Ross® 308 broilers used in this study were divided into seven groups of 35 birds each. Broilers were provided with magnetic drinking water (13,200 gausses) for 6 h daily from the 5th day and were challenged on days 14, 21, 28, and 35 using sodium chloride (700 mg/L), calcium sulfate (80 mg/L), lead acetate (500 mg/L), yeast extract 5% (5 mg/L), diazinon (2.5 mL/L), and E. coli O157:H7 (1.6 × 109 CFU/mL). A total of 2040 samples (96 diluent-Newcastle virus vaccine mixes, 96 microbial-magnetic water mixes, 231 sera, 231 intestinal swabs, and 1386 organ samples) were collected.

Results: An in vitro trial revealed highly significant (p<0.01) declines of 94.13%, 84.53%, and 10.31% in the Newcastle vaccine titer in water, saline, and magnetic water, respectively, and 54.91% and 39.89% in E. coli O157:H7 and S. Typhimurium survival, respectively, after 4 h. In all challenged groups, broilers exhibited highly significant (p<0.01) increases in performance, carcass/organs weight, immunoglobulin G, immunoglobulin M, and Lactobacillus counts; significant improvement in tissue architecture and biochemical parameters; and highly significant (p<0.01) reductions in cortisol, superoxide dismutase, and total bacterial and Enterobacteriaceae counts.

Conclusion: Magnetic water could maintain vaccine viability and vaccination efficiency, reduce microbial survival, and minimize the negative influence of all induced challenges.
Rethinking adult learning and education as global citizenship education: A conceptual model with implications for policy, practice and further research
Authors: Milana Marcella , Tarozzi Massimiliano
Published: June 2021

This article provides a conceptual analysis of the two domains of global citizenship education and adult education and learning, along with their similarities and differences. It begins by unpacking the ambiguous and contested concept of global citizenship education and proposing a critical vision of it, within a global social justice framework. Against this backdrop, the article argues for re-conceptualizing adult education and learning as global citizenship education, instead of considering the latter to be one of the key issues of the former. Their structural link is grounded in their common epistemological nature. The domains are interlocked to the extent that both (1) promote active citizenship skills, (2) strive towards equality and social justice on a global level and (3) adopt a values-based approach and promote transformative learning. In conclusion, an original ‘Four-dimensions approach to adult education and learning as global citizenship education’ conceptual model is advanced potentially to inform policymakers, practitioners and researchers. The model is made up of four basic components of adult education and learning as global citizenship education, namely: aims and scope (what for), contents and skills (what), processes and pedagogies (how), actors and learning environments (who).
O EFEITO DA TEMPESTIVIDADE CONTÁBIL NO GERENCIAMENTO DE RESULTADOS DE EMPRESAS BRASILEIRAS LISTADAS NA B3
Authors: Salgado Nayara de Nazaré Brasil , Souza Paulo Vitor Souza de
Published: June 2021

Objetivo: A tempestividade contábil consiste na disponibilidade da informação para os usuários atempo de poder influenciá-los em suas decisões. O objetivo deste artigo consiste em verificar o efeitoda tempestividade dos relatórios financeiros no gerenciamento de resultados de empresas brasileirasde capital aberto listadas na B3, utilizando três proxies para tempestividade: defasagem na publicação,perda do prazo da divulgação e a republicação.Método: A amostra é constituída por 172 empresas, no período compreendido entre 2010 e 2018. Avariável dependente representa o gerenciamento de resultados e foi mensurada pelo modelo de JonesModificado por Dechow, Sloan e Sweeney (1995). A variável independente representa a tempestividadee variáveis de controle foram incluídas, sendo elas: tamanho da empresa, empresas auditadas porBig Four, endividamento, governança corporativa, fluxo de caixa operacional e prejuízo do período.Utilizou-se regressões com dados em painel.Resultados: Os resultados fornecidos pelos seis modelos apontam que a tempestividade possui relaçãopositiva e significativa com o gerenciamento de resultados, isto é, as empresas que demoram e, atémesmo, que perdem o prazo de publicação de seus relatórios financeiros sinalizam maior gerenciamentode resultados. Os achados também denotam que empresas que republicam, de maneira espontâneaou obrigatória, tendem a um maior gerenciamento de resultados.Contribuições: Uma das principais contribuições da pesquisa consiste em evidenciar que atempestividade dos relatórios financeiros pode sinalizar práticas oportunistas da gestão por meiodo uso de gerenciamento de resultados, interferindo assim, no processo de tomada de decisões dosusuários da informação contábil.
A organização das mulheres camponesas no assentamento Juncal em Naviraí/MS
Authors: Silva Michely Cinquini Freire da , Fabrini João Edmilson
Published: June 2021

As mulheres camponesas do assentamento Juncal, em Naviraí/MS, criaram a Amaju (associação de mulheres do assentamento Juncal). Na Amaju, as mulheres elaboram uma variedade de produtos (pães, doces, biscoitos, artesanatos, dentre outros). Os produtos são comercializados no mercado local e institucional, o que contribui para geração de renda e autonomia das mulheres associadas. As mulheres desenvolvem também produção para autoconsumo vinculada ao trabalho reprodutivo. Embora organizadas a partir de uma base econômica, a Amaju se constitui num importante canal de participação das mulheres com desdobramento nas relações de gênero, política, etc.
Prólogo
Authors: Coudannes Mariela
Published: July 2021

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Design and Application of a Modified EWMA Control Chart for Monitoring Process Mean
Authors: Supharakonsakun Yadpirun , Areepong Yupaporn
Published: June 2021

The modified exponentially weighted moving average (modified EWMA) control chart is an improvement on the performance of the standard EWMA control chart for detecting small and abrupt shifts in the process mean. In this study, the effect of varying the constant and exponential smoothing parameters for detecting shifts in the mean of an autoregressive process with exogenous variables (ARX(p,r)) with a trend and exponentially distributed white noise on the standard and modified EWMA control chart was investigated. The performances of the two control charts were compared via their average run lengths (ARLs) computed by using explicit formulas and the numerical integrated equation (NIE) technique. A comparative study of the two ARL methods on the modified and traditional EWMA control charts shows that the modified schemes had better detection ability at all levels of shift size. Finally, two examples using real datasets on gold and silver prices are given to illustrate the applicability of the proposed procedure. Our findings advocate that the modified EWMA chart is excellent for monitoring ARX(p,r) processes with exponentially distributed white noise
La representación de la mujer migrante musulmana en la prensa italiana
Authors: Giardina Francesca , Marquez-Lepe Esther
Published: June 2021

Este trabajo analiza, desde una perspectiva de género, las representaciones que transmite la prensa italiana sobre las mujeres migrantes musulmanas. Una imagen que condiciona la manera en que la sociedad percibe a este grupo de población. Para ello se propone un análisis cualitativo de las noticias de tres periódicos italianos de tirada nacional: La Repubblica, Il Resto del Carlino, Corriere della Sera. Indagamos en el tipo de representaciones discursivas (temáticas e imágenes) que se hace sobre estas mujeres desde 2001 a 2018, así como en los contextos de producción (autoría, encuadre y temporalidad) de las noticias en las que aparecen. El análisis de la información nos muestra como la imagen de las mujeres migrantes musulmanas sigue construyéndose desde una mirada cosificada, patriarcal y etnocéntrica, asociada a estereotipos justificados en las ideas de sospecha, sumisión y opresión.
Multi-layer agility: a proposed concept of business agility in organizational behavior perspective
Authors: Saputra Nopriadi , Chumaidah Endang , Aryanto Riza
Published: June 2021

Turbulence in the business environment imposed large companies or market leaders to become more agile in doing business. Developing business agility can be implemented in many levels of business organization. This paper proposes a multi-layer perspective of business agility construct by examining construct validity through structural equation modelling. Based on organizational behavior theory, this paper proposes combining construct from three different perspectives of business agility: strategic agility from an organizational perspective, leadership agility from a group perspective, and learning agility from an individual perspective. The paper involved 477 supervisors and managers of Indonesian oil palm plantations as respondents. The data was analyzed by using Lisrel version 9.30. The result explains that the second-order construct is the best-fit construct for defining multi-layer agility as a measurement model.
Technology adoption on online learning during Covid-19 pandemic: implementation of technology acceptance model (TAM)
Authors: Utami Tri Lestari Wahyuning
Published: June 2021

Individual behavior in technology adoption can be predicted by perception and belief. Implementing TAM, this study aims to analyze the behavioral teaching staff in using Google Apps for online learning. This study examined the effect of perceived usefulness, perceived ease of use, and user training and support on behavioral intention to use technology. We analyzed 108 samples using SPSS Process Model 4 and Model 15 to examine the mediation effect and moderated mediation effect. Our results show that perceived usefulness is confirmed to mediate the perceived ease of use behavioral intention to use technology. However, moderated mediation effect is not supported. This study contributed to advance the empirical evidence on the implications of TAM in analyzing technology adoption.
Correlation between wrist circumference with blood pressure and creatinine level among elderly
Authors: Murbawani Etisa Adi , Noer Etika Ratna , Probosari Enny
Published: June 2021

Background: Hypertension is a highly prevalent health problem which incidence is greatest among the elderly. Hypertension may increase creatinine level and leads to other health problems like diabetes mellitus, kidney damage, and cardiovascular disease. Wrist circumference is a simple anthropometric measurement that can be used to identify hypertension and increasing level of serum creatinine.Objectives: To analyze the correlation of wrist circumference with blood pressure and creatinine level among the elderly.Materials and Methods: This was a cross-sectional study with a purposive sampling method. Subjects of this study were 84 women aged 60 years old or above at Unit Rehabilitasi Sosial Pucang Gading Semarang. The independent variable of this study was wrist circumference, and the dependent variables were systolic blood pressure, diastolic blood pressure, and creatinine level. The result was analyzed using the Spearman-rho test.Results: The participants of this research were 49% women aged 60-65 years old, with an average age was 65.5 years old. The prevalence of hypertension was 61.9%. Most hypertension incidence in this research was caused by high systolic blood pressure (50%), and the rest was caused by high diastolic blood pressure (3.9%) and both (46.1%). The level of creatinine was normal with an average level was 0.75 mg/dL. There was no correlation of wrist circumference with systolic blood pressure systolic (r=0.15; p=0.19), diastolic blood pressure (r=0.1; p=0.38), and creatinine serum (r=0.18; p=0.09) among elderly.Conclusions: There was no correlation of wrist circumference with blood pressure and creatinine level among the elderly.
Application of the general message of balanced nutrition during the pandemic coronavirus disease 2019 (COVID-19) in Mataram City
Authors: Wadhani Luh Putu Prema , Ratnaningsih Nani
Published: June 2021

Background: Coronavirus Disease 2019 (COVID-19) in 2020 became the limelight worldwide, including in Indonesia. Infection caused by this virus can be prevented by social distancing, physical distancing, and a healthy lifestyle. Maintaining nutritional intake by implementing balanced nutrition guidelines is very important to enhance the immune system.Objectives: This study aimed to determine the description of the application of balanced nutrition guidelines during the COVID-19 pandemic in the community in Mataram City.Materials and Methods: This research was a descriptive study with a survey approach, and the data taken were cross-sectional. This research was conducted in May-June 2020 in the community in the Mataram City taken by purposive sampling with inclusion criteria, namely women and men of productive age, domiciled in the city of Mataram, married status, and at least elementary school education. Respondents in this study were 460 respondents who were calculated using the Slovin formula. Data on the application of balanced nutrition guidelines were obtained using a questionnaire. Data from the results of this research were analyzed using descriptive methods.Results: There are as many as >90% of the community has implemented a general message of balanced nutrition in addition to the fifth message. As many as 89.9% of respondents did not apply the fifth general message of balanced nutrition in limiting consumption of sweet, salty, and fatty foods. The majority of applications >50% of general messages of balanced nutrition were applied by respondents aged 21-29 years, female, high education and work status. Conclusions: The application of the general message of balanced nutrition during the epidemic COVID-19 in Mataram City was implemented optimally, but this application was not carried out in the fifth message in limiting consumption of sweet, salty, and fatty foods.