bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of Varied Lecture Methods in Islamic Learning at Madrasah Tsanawiyah Pasuruan, Indonesia
Authors: Ali Jafar , Fauji Imam
Published: March 2022

The purpose of this study was to determine the learning planning of Islamic religious education using the various lecture methods at Mts Darussalam and to determine the application of the various lecture methods in learning Islamic religious education and the inhibiting factors and solutions in learning Islamic religious education using various lecture methods. This research is a field research using a qualitative approach. The subjects of this study were the teaching teacher of the Qur'an and hadith, the teacher of fiqh lessons and one class IX student of MTs Darussalam. The method used in this research is observation, interviews and documentation. While the analysis and interpretation of the data used is data reduction, data presentation, and drawing conclusions. The results of this study indicate that the application of the various lecture methods has been carried out optimally. The lecture method chosen is the discussion lecture method. Question and answer groups, assignments as well as demonstration and experimental methods. The implementation of learning using this method starts from the opening to the closing activities that run conducive and well. The inhibiting factors are the time factor of the facilities and infrastructure, and the supporting media that must be needed in the application of the method. However, the solution to the inhibiting factor is to maximize time and complete the learning media infrastructure needed in the learning process.
Planetary Genealogy
Authors: Burkhardt Christoph
Published: March 2022

The detection of exoplanets and accretion disks around newborn stars has spawned new ideas and models of how our Solar System formed and evolved. Meteorites as probes of geologic deep time can provide ground truth to these models. In particular, stable isotope anomalies in meteorites have recently emerged as key tracers of material flow in the early Solar System, allowing cosmochemists to establish a “planetary isotopic genealogy”. Although not complete, this concept has substantially advanced our understanding of Solar System evolution, from the collapse of the Sun’s parental molecular cloud to the accretion of the planets.
Vibration characteristics analysis of face gear transmission system considering gyroscopic effect
Authors: Li Xiaozhen , Su Kuo , Li Tongjie , Zhang Liyong
Published: March 2022

To improve the dynamics of the face gear transmission system, a nonlinear dynamics model considering gyroscopic effects and including parameters such as time-varying meshing stiffness, meshing damping, tooth side clearance, support stiffness and damping is developed. The Runge-Kutta method was used to solve the nonlinear kinetic equations and analyze the accuracy and reasonableness of the model calculation results. The vibration displacement, vibration velocity and vibration acceleration along each direction of the face gear and straight cylindrical gear were analyzed, and the torsional vibration characteristics of the center of mass of the two gears were studied.
MARCAS E MODIFICAÇÕES CORPORAIS (BM) EM UMA REFLEXÃO SOBRE REIVINDICAÇÕES DE PODER E OBSOLESCÊNCIA DA MEMÓRIA HUMANA
Authors: Barreto de Souza Celestino Tayara
Published: March 2022

O presente artigo parte do interesse crescente observado nos últimos anos de pessoas em promoverem marcas de modificações em seus corpos em diversos aspectos, desde os mais externos, impactando na economia de capitais sociais e simbólicos, na reprodução de capitais raciais de desigualdades sociais e nos processos de reivindicação de poder pelo corpo até a crítica das ontologias do corpo. Em seguida, avança para a reflexão sobre como as sociedades marcadas pela cultura de modificações corporais podem estar antecipando diversificados processos de modificações corporais como um projeto de corpo modificado (Body Modification) com tecnologias corporais atualizadoras do corpo e definidoras, neste corpo, de componentes desejáveis bem como de componentes obsoletos, dos quais a memória humana.
TECNOPOLÍTICAS DO FAKE VÍRUS NA ECONOMIA SEXUAL DA MORTE
Authors: Oliveira Junior Ribamar José de
Published: March 2022

O copo de leite na mesa, a caixa de hidroxicloroquina na mão e o conteúdo impróprio na piada infantil, as lives transmitidas por Jair Bolsonaro durante o primeiro ano da pandemia da Covid-19 no Brasil parecem explorar a realidade e cosmetizar a necropolítica, sobretudo, na produção de verdade que busca a prerrogativa do poder. Através da analítica foucaultiana do discurso, foi possível notar nas transmissões de maio a setembro de 2020 como o modo lifestream pode construir o personagem político do mito por meio de ficções que parecem operar como terapia ideológica para determinados grupos. A supremacia branca, o panóptico ingerível do farmacopoder e a pornografia sutil aparecem como alguns dos eixos do capitalismo gore no Brasil que, no efeito de placebo, hasteia a bandeira nacional nos valores da família e no argumento da cristofobia.
“IBO AZUL” A TECEDURA DA SEDUÇÃO NO COTIDIANO DO CORPO, DO ESPAÇO E DA LINGUAGEM
Authors: Anjos Neto João Dantas dos , Soares Cardoso Beatriz
Published: March 2022

“Ibo Azul” é o conto selecionado para apresentar uma reflexão referente a tecedura da sedução no cotidiano do corpo, do espaço e da linguagem, sendo esse o objetivo geral. Esses elementos serão analisados em trechos específicos do referido conto. Além da análise da linguagem e dos aspectos simbólicos presentes no enunciado, focalizaremos as significações metafóricas para as personagens dessa narrativa. Tem-se como objetivos específicos: contextualizar o conto antropologicamente; analisar o modo como a tecedura da sedução se configura na escrita literária de João Paulo; percorrer as trilhas do cotidiano do corpo, do espaço e da linguagem; apresentar o conteúdo teórico que serve de base para a reflexão proposta; interpretar os elementos simbólicos que se entrelaçam e se interpõem na narrativa. A partir das representações culturais utilizou-se métodos de análise centrada na antropologia da linguagem, partindo da metáfora como figura de linguagem, e da semiose literária; fazendo um recorte nas incursões pelo universo do corpo, do espaço e da linguagem.
FEMININO ANCESTRAL E SUA POTÊNCIA NO PARQUE NACIONAL SERRA DA CAPIVARA – PNSC
Authors: Justamand Michel , Alves Balbino Ana Cristina , F. de Oliveira Gabriel , José Rampaneli de Almeida Vitor , Caldeiras Ana , Rabello Gabriela
Published: March 2022

Este artigo é sobre as possibilidades da apreensão das mais diversas atividades femininas realizadas ancestralmente, registradas nas artes rupestres, em especial, as pinturas. Feitas dentro ou na região do entorno do Parque Nacional Serra da Capivara, no sudoeste do estado do Piauí, Brasil. A partir de trabalhos de campo realizados por equipe interdisciplinar, entre 2003 e 2018. Nessas investidas a campo se registraram cenas de parto, sexo, afazeres cotidianos entre outras ações, possivelmente, efetuadas por representações do feminino, nas rochas da região.
“CHORA, JORNALISTA”
Authors: Zago Luiz Felipe , Da Fonseca de Oliveira Matheus Henrique
Published: March 2022

Este artigo descreve e analisa as formas de crítica à imprensa e ataque à identidade profissional de jornalistas existentes em tweets de Jair Bolsonaro e seus três filhos, Carlos Bolsonaro, Eduardo Bolsonaro e Flávio Bolsonaro. O objetivo é descrever e analisar as críticas à imprensa e os ataques à identidade profissional de jornalistas publicadas nos seus respectivos perfis. Foram arquivadas 621 postagens feitas pelos políticos nos primeiros 15 dias de março de 2020, das quais 135 apresentaram conteúdos pertinentes ao recorte temático proposto. A análise aponta o protagonismo exercido pelas redes sociais digitais na mediação do debate público político. Resgata as relações que têm sido estabelecidas historicamente no Brasil entre o poder político e a imprensa, sobretudo no que toca à identidade profissional dos jornalistas. Reflete sobre a imprensa como instituição que historicamente ocupou o papel de Poder Moderador e supostamente garantidor da democracia. A partir da observação do conteúdo dos tweets arquivados, este trabalho identificou três finalidades principais nas publicações do clã: atacar a imprensa tradicional em geral, atacar veículos de comunicação específicos e atacar individualmente jornalistas. Constatou-se que o presidente e seus filhos tentam esvaziar a credibilidade da imprensa e atuam para fazer de seus perfis nas redes sociais os únicos meios fidedignos para informar a população sobre política.
EXPERIÊNCIA DO FEMININO FRENTE ÀS HOSTILIDADES DA CIDADE
Authors: Barros Erna
Published: March 2022

A proposta deste artigo se volta a uma leitura do graffiti enquanto fenômeno urbano em diálogo com a estrutura da cidade como espaço de disputas a partir de uma perspectiva de gênero, buscando contribuir para uma discussão sobre o transitar das mulheres pelo ambiente público “por sobre os ombros” de grafiteiras que ressignificam estes espaços, apoiadas na representação de entendimentos sobre uma cidade pensada e planejada segundo uma ideia de universalidade do humano, ou seja, uma perspectiva hegemônica do masculino em detrimento do feminino. O texto busca refletir sobre a experiência das grafiteiras na Grande Aracaju, a partir de relatos apreendidos durante saídas para grafitar, junto a suas práticas cotidianas. Nesse contexto questões como o medo da cidade e a hostilidade de gênero são analisadas como formas de experimentar a cidade, compartilhando assim algumas impressões dessas saídas, apresentando as falas de algumas interlocutoras junto às impressões da autora sobre os caminhos que percorremos na cidade.
UM LÉXICO DE FLUIDOS SÓLIDOS
Authors: Guedes Brigante (Tradutor) Gustavo
Published: March 2022

Em nossas discussões acerca do tema de fluidos sólidos, constantemente recorremos a palavras cotidianas, várias delas de derivação anciã e ricas em associação. Nós decidimos fazer uma lista de algumas das palavras que surgiram com maior frequência – exceto aquelas que já figuram como protagonistas das contribuições individuais – e distribuir entre nós a tarefa de escrever um tipo de mini-biografia para cada. O léxico resultante com 19 entradas, variando de ‘nuvem’ e ‘concreto’ para ‘onda’ e ‘madeira’, serve como uma conclusão para a coleção como um todo.

 

Tradução de “A Solid Fluid Lexicon”, publicado originalmente em SAGE Journals, DOI: https://doi.org/10.1177/02632764211030976, 2021, em inglês, se enquadra nos termos do licenciamento gratuito, sem necessidade de autorização formal, previsto pela Creative Commons. A licença, sob a sigla CC BY-NC 4.0 (“Creative Commons by noncomercial use” - https://creativecommons.org/licenses/by-nc/4.0/), abrange artigos “abertos” da SAGE Journals e contempla apenas traduções cujas finalidades não sejam comerciais, desde que a fonte e licença sejam explicitadas no documento traduzido. Traduzido por Gustavo Guedes Brigante, Doutorando em Ciências Sociais (UFRN) e Mestre em Ciências Sociais (PUC/SP).
Assessment of the Impact of the Covid-19 Pandemic on the Incomes and Adaptation of the Population of the Region To It: Statistical Approach
Authors: Kremlev N. D. , Drozdova I. A.
Published: March 2022

The aimof the study is to determine the impact of the COVID-19 pandemic and the self-isolation regime announced in Russia on the incomes of the population. The relevance of the study is connected with the problems of reflecting the pandemic, searching for patterns and its interrelations with incomes, health, living conditions of the population. The emergence of coronavirus disease (March 2020), quickly spread to all regions of the country, in 2021 the fourth record wave of morbidity and mortality of the population was recorded.The research methodsare the theory and methodology of income of the population used by the Federal State Statistics Service, corresponding to international norms and standards, including the system of national accounts. To determine the directions of the impact of the COVID-19 pandemic on the incomes of the population of the region, the method of analytical groupings (stochastically deterministic relationships), as well as the method of comparing parallel series, the index method and interregional data evaluation analysis were used.The resultsof the study: the use of a statistical approach to assess and determine the impact of the COVID-19 pandemic on the real incomes of the population allowed us to determine the features of the spread of the disease in the regions of the Ural Federal District. The conclusion is made: the spread of COVID-19 in 2020-2021 did not have a significant impact on the real monetary incomes of the population in the regions of the Ural Federal District, despite the increase in the morbidity of people. The population quickly adapted to the pandemic, many enterprises were operating normally, and the state took prompt measures to reduce tensions and support the population and the health system in the country. The oppositely directed factors of the impact of the pandemic, leading to negative and positive consequences of real incomes of the population, have been identified. The level and degree of influence of the morbidity of the population on the income of the population are determined.Conclusion: the use of a statistical approach makes it possible to improve the quality of information, to determine the positive and negative factors of the COVID-19 pandemic’s impact on incomes and the level of adaptation of the region’s population to it. The adaptation of the population to the coronavirus will continue for several more years and longer, and the waves of the disease will decrease as medicines are created. The study makes it possible to assess not only the main directions of influence on the real monetary incomes of the population, but also the quality of decisions made by management structures.
Enhanced Bioavailability and Higher Uptake of Brain-Targeted Surface
Engineered Delivery System of Naringenin developed as a Therapeutic for
Autism Spectrum Disorder
Authors: Kuhad Anurag , Bhandari Ranjana , Paliwal Jyoti K
Published: March 2022

Background:

Neuroinflammation resulting from oxidative and nitrosative stress is associated
with various neurological disorders and involves the generation of pro-inflammatory cytokines and
microglial activation. Dietary phytochemicals are safer and more valuable adjunct neurotherapeutic
agents which can be added to the therapeutic regimen. These compounds provide neuroprotection by
the modulation of various signaling pathways.

Introduction:

Naringenin (NGN) is a phytochemical having low oral bioavailability because of poor
solubility, and adding to this limitation is enhanced efflux by P-glycoprotein transporters in neuroinflammatory
diseases.

Methods:

Hence, as a solution for these limitations, naringenin encapsulated poly-lactic-co-glycolic
acid (PLGA) nanocarriers were developed using the nanoprecipitation technique and coated with 1%
glutathione (GSH) and 1% Tween 80 to enhance brain delivery.

Results:

Coated and uncoated NGN-PLGA nanoparticles (NGN-PLGA-NPs) were spherical, monodispersed,
stable, and non-toxic, with a particle size of less than 200 nm. They had negative zeta-potential
values, 80% entrapment efficiency, and sustained drug release of 81.8% (uncoated), 80.13%, and
78.43% (coated) in 24 hours. FT-IR, DSC, PXRD, and NMR confirmed the drug encapsulation and
coating over nanoparticles. In-vivo brain uptake showed greater fluorescence intensity of the coated
nanoparticles in the brain than uncoated nanoparticles. In addition, there was a 2.33-fold increase in
bioavailability after coating compared to naringenin suspension and enhanced brain uptake.

Conclusion:

Present studies indicate sustained and targeted brain delivery of naringenin via the ligandcoated
delivery system by inhibiting enhanced P-glycoprotein (P-gp) efflux occurring in autism spectrum
disorders due to neuroinflammation.
Look Into My Onco-forest - Review of Plant Natural Products with
Anticancer Activity
Authors: Michalak Izabela , Püsküllüoğlu Mirosława
Published: March 2022

Cancer is a multistage process that numerous modalities including systemic treatment can treat. About half of the molecules that have been approved in the last few decades count for plant derivatives. This review presents the application of tree/shrub-derived biologically active compounds as anticancer agents. Different parts of trees/shrubs - wood, bark, branches, roots, leaves, needles, fruits, flowers, etc. - contain a wide variety of primary and secondary metabolites that demonstrate anticancer properties. Special attention was paid to phenolics (phenolic acids and polyphenols, including flavonoids and non-flavonoids (tannins, lignans, stilbenes)), essential oils, and their main constituents such as terpenes/terpenoids, phytosterols, alkaloids, and many others. The anticancer properties of these compounds are mainly attributed to their strong antioxidant prop-erties. In vitro experiments on various cancer cell lines revealed a cytotoxic effect of tree-derived extracts. Mechanisms of anticancer action of the extracts are also listed. Examples of drugs that successfully underwent clinical trials with well-established positions in the guidelines created by oncological societies are provided. The review also focuses on directions for the future in the devel-opment of anticancer agents derived from trees/shrubs. Applying biologically active compounds de-rived from trees and shrubs as anticancer agents continuously seems promising in treating systemic cancer.
Computational Modeling on Binding Interactions of Cyclodextrin s with the Human Multidrug Resistance P-glycoprotein Toward Efficient Drug-delivery System Applications
Authors: González-Durruthy Michael , Concu Riccardo , Dias Soeiro Cordeiro Maria Natália , Osmari Vendrame Laura F. , Ortiz Martins Mirkos , Zanella Ivana , Ruso Juan Manuel
Published: March 2022

Background:

Herein, molecular docking approaches and DFT ab initio simulations were combined for the first time, to study the key interactions of cyclodextrins (CDs: α-CD, β-CD, and γ-CD) family with potential pharmacological relevance and the multidrug resistance P-gp protein toward efficient drug-delivery applications. The treatment of neurological disorders and cancer therapy where the multiple drug-resistance phenomenon mediated by the P-gp protein constitutes the fundamental cause of unsuccessful therapies.

Objective:

To understand more about the CD docking mechanism and the P-gp.

Methods:

In order to achieve the main goal, the computational docking process was used. The observed docking-mechanism of the CDs on the P-gp was fundamentally based on hybrid backbone/side-chain hydrophobic interactions,and also hybrid electrostatic/side-chain interactions of the CD-ligands' OH-motifs with acceptor and donor characteristics, which might theoretically cause local perturbations in the TMD/P-gp inter-residues network, influencing ligand extrusion through the blood-brain barrier. P-gp residues were conformationally favored. Despite the structural differences, all the cyclodextrins exhibit very close Gibbs free binding energy values (or affinity) by the P-gp binding site (transmembrane domains - TMDs).

Results:

The obtained theoretical docking-mechanism of the CDs on the P-gp was fundamentally based on hybrid backbone/side-chain hydrophobic interactions, and also hybrid electrostatic/side-chain interactions of the OH-motifs of the CD-ligands with acceptor and donor properties which theoretically could induce allosteric local-perturbations in the TMDs-inter-residues network of P-gp modulating to the CD-ligand extrusion from the blood-brain-barrier (or cancer cells).

Conclusion:

Finally, these theoretical results open new horizons for evaluating new nanotherapeutic drugs with potential pharmacological relevance for efficient drug-delivery applications and precision nanomedicine.
Supported Ionic Liquids and their Applications in Organic Transformations
Authors: Singh Pradeep Pratap , Ambika
Published: March 2022

Ionic liquids are one of the greener solvents which have emerged as a replacement for toxic and harmful volatile organic solvents. In the past decade, the concept of supported ionic liquids (SILs) has attracted the attention of the scientific community due to their unique chemical and phys-ical properties. SILs can be synthesized by coating a thin layer of IL film onto/into the surface of solid support. They can be classified as supported IL phase catalyst, solid catalyst with IL and sup-ported IL catalysis. SILs demonstrated the combined properties of both heterogeneous and homoge-neous catalysts. These ILs offer several advantages such as enhanced stability, reusability, recovera-bility, easy product isolation, absence of IL leaching, as compared to conventional solvents. In this review, various aspects of SILs, classification, method of preparation and their applications in var-ious organic transformations such as cross-coupling reactions, oxidation, reduction, synthesis of dif-ferent heterocyclic compounds, biocatalytic reactions etc., have been discussed.
A Molecular Insight into Pyrazole Congeners as Antimicrobial, Anticancer,
and Antimalarial Agents
Authors: Karati Dipanjan , Mahadik Kakasaheb Ramoo , Trivedi Piyush , Kumar Dileep
Published: March 2022

Background:

Pyrazole is a bioactive heterocyclic congener with numerous biological and
pharmacological functionalities. Due to their multiple prospective applications, developing innovative
and novel pyrazoles and analogs, revealing revolutionary methods for synthesizing this nucleus,
investigating diverse potencies of that heterocycle, and exploring possible pyrazole applications are
becoming increasingly relevant.

Objectives:

Pyrazole scaffolds have been proven successful as antimicrobial, anticancer, and antimalarial
therapeutics against multiple targets like DNA gyrase, topoisomerase IV, Hsp90, and several
kinase enzymes. For this variability in the biotic zone, their moiety has gained the attention of many
scientists interested in researching chemical and pharmacological profiles.

Results:

The review covers pyrazole scaffolds with a variety of biological functions and attempts to
connect the structure-activity relationship. Multiple pyrazole analogs have been produced as lead
compounds, and their activities have been evaluated.

Conclusion:

The combination of pyrazole with other pharmacophores in a molecule might lead to
novel potent therapeutic medicines, which could aid in the development of potent lead compounds.
A Review of Bayesian Networks Applications for Electrical Systems
Authors: Hamza Zerrouki
Published: March 2022

The development in the field of electrical energy has been growing increasingly due to
the need for this energy in daily life. The reliability and safety of electrical power systems and
equipment represent complex problems that are difficult to solve by conventional methods such as
Fuzzy Logic and Artificial Neural Networks. Bayesian network is recently used to overcome some
limitations in conventional methods. This paper represents a bibliographic review about the use of
Bayesian networks in the field of electric systems. This paper seeks to answer the following questions:
(i) What are the areas of interest? (ii) What are the most active countries in this field?? (iii)
Who are the most participating authors in this field? (iv) which year witnessed the largest number of
publications? (v) What is the most widespread field related to this research? (vi) What is the most
used system in terms of application? This field witnesses a slight increase in the number of publications
in the last two decades (1999–2021), with a note of a sharp increase in publishing in the last
two years. It is observed that reliability assessment and fault diagnosis are the most common fields.
Furthermore, it is found that China and USA are the active countries in this field. Electric Power and
Energy Systems Journal and IEEE Transactions on Power Systems Journal are the lead source documents,
and most of the documents used electric power systems as an application. This paper will
help researchers to know the versability features of BN and to identify the gaps in the use of BN in
electric domains.
Adaptation of an In-Person Internship to a Virtual Format for Public Health Undergraduates (Preprint)
Authors: Kernan William D , Basch Corey H
Published: March 2022

UNSTRUCTURED

The disruption of traditional, in-person learning due to the COVID-19 pandemic necessitated the rapid development and use of revised and novel learning opportunities using a variety of remote instructional methodologies. This viewpoint describes the process used by an undergraduate Public Health program to transition a traditional, in-person, semester-long, 480-hour internship to a virtual-only learning experience guided by the existing student learning outcomes. Working closely with public health professionals at existing internship agencies, alumni from the program, student interns, and program faculty developed a modified virtual internship composed of 6 components. The development of this modified virtual internship model was guided by previous research on the components of successful internships and the elements of high-impact learning practices.
Second wave of COVID-19 in India could be predicted with genomic surveillance of SARS-CoV-2 variants coupled with epidemiological data: A tool for future (Preprint)
Authors: Kumar Ashutosh , Asghar Adil , Dwivedi Prakhar , Kumar Gopichand , Narayan Ravi K. , Jha Rakesh K. , Parashar Rakesh , Sahni Chetan , Pandey Sada N.
Published: March 2022

UNSTRUCTURED

India has witnessed a devastating second wave of COVID-19, which peaked during the last week of April and the second week of May, 2021. We aimed to understand whether the arrival of second wave was predictable and whether it was driven by the existing SARS-CoV-2 strains or any of the emerging variants. We analyzed the monthly distribution of the genomic sequence data for SARS-CoV-2 from India and correlated that with the epidemiological data for new cases and deaths, for the corresponding period of the second wave. Our analysis shows that the first indications of arrival of the second wave were observable by January, 2021, and by March, 2021 it was clearly predictable. B.1.617 lineage variants drove the wave, particularly B.1.617.2 (a.k.a. delta variant). We propose that genomic surveillance of the SARS-CoV-2 variants augmented with epidemiological data can be a promising tool for predicting future COVID-19 waves.
Trajectories of Uremic Symptom Severity and Kidney Function in Patients with Chronic Kidney Disease
Authors: Wulczyn Kendra E. , Zhao Sophia H. , Rhee Eugene P. , Kalim Sahir , Shafi Tariq
Published: March 2022

Background and objectives

Uremic symptoms, including fatigue, anorexia, pruritus, nausea, paresthesia, and pain, are attributed to the accumulation of organic waste products normally cleared by the kidneys, but whether kidney function is the primary driver of changes in symptom severity over time is not known. The goal of our study was to evaluate the association between eGFR and uremic symptom severity score in patients with CKD.

Design, setting, participants, and measurements

We identified 3685 participants with CKD not on dialysis in the prospective, observational Chronic Renal Insufficiency Cohort (CRIC) Study with baseline assessment of eGFR and uremic symptom severity. Symptoms were assessed by separate questions on the Kidney Disease Quality of Life-36 instrument (zero- to 100-point scale). The longitudinal association between eGFR and uremic symptom severity score was examined with multivariable adjusted linear mixed-effects models with random intercepts and random slopes.

Results

The mean±SD eGFR at baseline was 44±15 ml/min per 1.73 m2, and participants had a median of six (interquartile range 3–11) simultaneous assessments of eGFR and uremic symptoms over the duration of follow-up. The most prevalent symptoms at baseline were pain (57%), fatigue (52%), paresthesia (45%), and pruritus (42%). In adjusted models, a decrease in eGFR of 5 ml/min per 1.73 m2 was associated with a worsening of the symptom severity score by two points or less for each uremic symptom (P<0.01; zero- to 100-point scale). The association between eGFR and uremic symptom severity score was nonlinear. When starting from a lower initial eGFR, a 5 ml/min per 1.73 m2 decrease in eGFR was associated with a greater magnitude of uremic symptom worsening.

Conclusions

The prevalence of uremic symptoms in CKD is high, with significant variability in patient symptom change over time. Declines in eGFR were associated with worsening of uremic symptom severity, but the magnitude of these changes is small and of uncertain clinical significance.
ВЫСОКИЕ АМБИЦИИ НИЗКИХ ОРБИТ
Authors: Петрова С.
Published: March 2022

16 февраля состоялась ежегодная конференция #SpaceCom Digital Russia 2022. Эксперты в области спутниковых коммуникаций обсудили перспективы трансформации отрасли спутниковой связи, динамику ее развития, а также глобальные тренды на стыке телекома и инфокоммуникаций. Специалисты разошлись в оценках ряда технологических решений, систем и резонансных проектов, за развитием которых с интересом наблюдают представители не только спутниковой индустрии.
THE DYNAMIC CAUSAL RELATIONSHIP BETWEEN OIL PRICE AND ECONOMIC GROWTH IN OIL-IMPORTING SSA COUNTRIES: A MULTIVARIATE MODEL
Authors: Akinsola Motunrayo O. , Odhiambo Nicholas M.
Published: March 2022

This study examines the causal relationship between oil price and economic growth in 14 oil-importing countries in sub-Saharan Africa during the period 1990 to 2018. The countries are further divided into two groups, namely seven low-income countries (LICs) and seven middle-income countries (MICs) in order to test whether the causality between oil price and economic growth depends on the countries’ income levels. Unlike previous studies that used a bivariate model, this study employs a multivariate Granger-causality model, which incorporates oil consumption and real exchange rate as intermittent variables in a bivariate setting between oil price and economic growth. The study employs panel cointegration and the panel Granger-causality tests to examine this linkage. The results of the study show that in the short run, there is a bidirectional causality between oil price and economic growth for the entire dataset, and both for the LICs and MICs. However, in the long run, there is a bidirectional causal relationship between oil price and economic growth for the entire dataset and MICs, but a unidirectional causality from economic growth to oil price for the LICs. Overall, the study found a feedback relationship between oil price and economic growth to be predominant.
THE PANDEMIC WAVES’ IMPACT ON ROMANIAN E-MARKET: A NON-LINEAR REGRESSION MODEL
Authors: Boldea Costin Radu , Boldea Bogdan Ion
Published: March 2022

The SARS-COV2 pandemic had a strong impact on the Romanian and European e-Market, manifested by the explosive increase in online sales, especially at the beginning of the two waves of epidemic, in spring and autumn. Using a statistical regressive analysis of monthly change in the volume of online sales in Romania, we propose a non-linear regression model of growth of this commercial sector that take into account the economic and socials effects of the three pandemic waves in 2020-2021, combining logistic equations of growth with attenuated quasi-periodical variations of market. The model allows a prediction of the overall behavior of online buyers for 2021 and 2022, similar to last year, but with annual growth peaks slightly less pronounced than in 2020.
Inhibiting Effect of Natural Plant Leaves Extract Used as Green Corrosion Inhibitor for Mild Steel in Acidic Media
Authors: Ade Suraj B.
Published: March 2022

Abstract: Inhibition of corrosion of mild steel in hydrochloric acid by natural plant leaves extract of of Bahunia Varigata (Aapta), Azadirachta Indica (Neem), Pongamia Pinnata (Karanj), Santalum Album (Sandal Wood) and Astonia Scholaris (Saptparni) has studied using weight loss measurement. It was, found that the leaves extract act as a good corrosion inhibitor for mild steel in all concentrations of the extract. The inhibition action depends on the concentration of the leaves extract in the acid solution. Results for weight loss measurements indicate that inhibition efficiency increase with increasing inhibitor concentration. Extract of natural plants is one of the most important metallic corrosion inhibitors. They are readily available, nontoxic, environmentally friendly, biodegradable, highly efficient, and renewable. Several organic compounds with heteroatom such as N, O, S and P present in the plant extracts are, adsorbed directly onto the metals surface through polar atoms and thereby forming the protective layer. Plants represent a class of interesting source of compounds currently being, explored for use in metal corrosion protection in most systems, as possible replacement of toxic synthetic inhibitors. This paper discusses the different types of natural green plant leaves extract inhibitors for corrosion control of mild steel in acid medium. Keywords: Corrosion, Inhibition, carbon steel, Weight loss and natural plant leaves extract.
KONSEP SIMBOL KEBUDAYAAN: SEJARAH MANUSIA BERAGAMA DAN BERBUDAYA
Authors: Sinta Dewi Ning Ratna
Published: March 2022

Humans as God's most perfect creatures create their own culture and preserve it from generation to generation. Culture is part of the journey of human life. Based on history, culture or culture is something that cannot be separated from human life. Culture is the result of human creativity. Culture exists because of humans and humans develop a variety of cultures according to their needs and desires. Culture develops according to the human environment. Apart from being social creatures, humans also interact with fellow humans according to their habits and habits which in the end become a culture that is always carried out. Culture is a product of human creation. In other words, culture exists because humans created it and humans can live in the midst of the culture they created. Culture will continue to live when humans become residents and culture has enormous uses for all aspects of human life. Culture, which is a universal phenomenon, where every human being in the world has a culture, even though the shape (symbol) and style, of the culture that is owned varies from various tribes, nations, and races. In the end, the culture that humans have shows their similarities in accordance with human nature and every culture has a place and society is a place for that culture.
Análisis de la motivación extrínseca y la retroalimentación afectiva en la interacción profesor-alumno
Authors: García Corona Valeria , Ruiz Carrillo Edgardo , Cruz González José Luis , Gómez Aguirre Cristina
Published: March 2022

El objetivo del presente estudio fue identificar y analizar cuáles son las categorías de retroalimentación afectiva que se presentan con mayor incidencia y la interpretación de contenido de las mismas, y si esto se refleja en la motivación extrínseca del alumno de medicina, es decir, en su participación activa dentro la clase. Se videograbó a un grupo de medicina, se transcribió y codificó la clase con base en el instrumento de categorías motivacionales, obteniendo frecuencias y porcentajes de cada una de ellas. También, se realizó un análisis del discurso, seleccionando los discursos más relevantes de algunas de las categorías para su análisis. Se encontró que la retroalimentación afectiva que el profesor ofrece fomenta la participación del alumno; la apreciación, el reconocimiento y el ánimo que el profesor da sobre la respuesta del alumno, hace que éste participe, impulsándolo a contestar correctamente las preguntas abiertas o directas que el profesor ha formulado.
Análisis factorial de la Escala de Bienestar Psicológico de Ryff en una muestra de universitarios mexicanos
Authors: Osorio Guzmán Maricela , Prado Romero Carlos
Published: March 2022

Antecedentes: Ryff concibió el bienestar psicológico desde claves eudaimónicas, construyendo para su medida las Psychological Well-Being Scales (PWBS) que incluyen seis dimensiones. Esta escala, se ha usado en países, muestras etarias, idiomas y versiones en cuanto a la cantidad de ítems diferentes; por lo que su validez ha sido puesta a prueba debido a que las soluciones factoriales varían considerablemente. El objetivo fue analizar la validez factorial de los principales modelos teóricos del bienestar propuestos en la literatura, para determinar cuál de ellos presenta los niveles de ajuste más satisfactorios en población mexicana universitaria. Método. Se aplicó el PWBS a 1400 estudiantes de 10 licenciaturas de la Universidad Nacional Autónoma de México. Se probaron los modelos mediante un análisis factorial confirmatorio, se calculó la fiabilidad total y por áreas a partir de alfa de Cronbach y omega. Resultados: Se encontraron dos estructuras de ajuste factorial satisfactorias, una de 4 factores (17 reactivos) y otra de 6 factores (20 ítems); con índices generales de fiabilidad adecuados, e índices por áreas que van de 0.642 a 0.604 y 0.442 a 0.754 respectivamente. Conclusiones: Se proponen dos versiones válidas de la escala de bienestar para evaluar el constructo en universitarios mexicanos.
Discordant population structure within rhizobium divided genomes and between rhizobia and legume hosts in their native range
Authors: Riley Alex , Grillo Michael , Epstein Brendan , Tiffin Peter , Heath Katy
Published: March 2022

Symbiosis often occurs between partners with distinct life history
characteristics and dispersal mechanisms. Bacterial symbionts often have
genomes comprised of multiple replicons with distinct rates of evolution
and horizontal transmission. Such differences might drive differences in
population genetic structure between hosts and symbionts and among the
elements of the divided genomes of bacterial symbionts. These
differences might, in turn, shape the evolution of symbiotic
interactions and bacterial evolution. Here we use whole genome
resequencing of a hierarchically-structured sample of 191 strains of
Ensifer meliloti collected from 21 locations in the native range to
characterize population structure of this bacterial symbiont and its
host plant Medicago truncatula. E. meliloti genomes showed high local
(within-site) variation and little isolation by distance. This was
particularly true for the two symbiosis elements pSymA and pSymB, which
have population structures that are similar to each other, but distinct
from both the bacterial chromosome and the host plant. The differences
in population structure may result from differences in mobility or
selection driving bacterial adaptation to life in the soil versus in
association with plants. Discordant population structure between hosts
and symbionts indicates that geographically and genetically distinct
host populations in different parts of the range might interact with
genetically similar symbionts, potentially minimizing the potential for
local specialization.
A Process Model for Improving Sleep through Clinical Dohsa Hou: The Subjective Experiences of Patients with Cerebral Palsy
Authors: S Harada
Published: March 2022

People with cerebral palsy often have sleep disorders, such as difficulty falling asleep or waking up often during the night, due to their physical disabilities. The main method of treatment for this is medication. While the efficacy of pharmacotherapy has been acknowledged, it is also necessary to consider issues that have been raised in recent years concerning the side effects of sleeping pills as well as the importance of non-pharmacological approaches. This study discusses a non-pharmacological technique called Dohsa Hou or Movement Therapy in English. Dohsa Hou has for many years helped people with cerebral palsy to foster movement control and improve physical disability. There have also been reports of sleep improvement in people with cerebral palsy in recent years. In the present study, several people with cerebral palsy were chosen and interviewed about their experiences of improving their physical disabilities and sleep disorders through Dohsa Hou. The participants had to recall their experiences of practicing the therapy. The collected data were analysed using the Trajectory Equifinality Model. The results of the analysis suggested the improvement of chronic tension in the ankle, hip joint, and upper body regions as important physical experiences that lead to improved sleep in people with cerebral palsy. In addition to acquiring control to relax the body, it also showed that the acquisition of an appropriate gravitropic posture played an important role in improving the above-mentioned areas of chronic tension.
Modelling and improving the vapour deposition efficiency of a novel PVD-based galvanising process
Authors:   , Carlos James P.
Published: March 2022

Physical vapour deposition (PVD) is being developed by Tata Steel as a continuous coating process for a steel substrate. Typically, the process is undertaken in low to medium vacuum conditions (0.001-0.1 Pa) to reduce contamination of the Zinc vapour and minimise impedance to the vapour flow towards the substrate. This project centers around using computational models developed in OpenFOAM and ANSYS Fluent, to simulate PVD coating process with the aim of finding and optimising process parameters to enhance deposition yield. The lid-driven cavity benchmark model showed that the software packages mentioned, produced matching results to each other and against the benchmark data. Another benchmark, a vacuum interrupter model, was used to validate OpenFOAM’s DsmcFoam, which is a stochastic particle-based Direct Simulation Monte Carlo (DSMC) model. It allowed modelling of low pressure (high Knudsen number) flows and results showed similar deposition trends to the benchmark data. The inlet profile models focused on the coating uniformity and vapour distribution width. The models showed that an array of nozzles and slits produced wider deposition distribution when compared to a wide slit profile and, generally, nozzles produced a more uniform deposition distribution across the substrate when compared to slits. Additionally, for a specific inlet to substrate distance, nozzle spacing needs to be configured accordingly to ensure uniform deposition. For a gap of 20 mm, a nozzle spacing of either 6 and 10 mm; and for a 10 mm gap a spacing of 6 mm is suggested. Finally, the inlet to substrate models predicted coating yields of over 99% at low vacuum conditions (1-10 Pa). Generally, pressure is inversely proportional to the yield and in terms of reducing waste coating material, 10 Pa vacuum pressure is recommended. Moreover, the accretion model showed that coating chamber pressure is inversely proportional to the velocity of the vapour exiting the nozzle if the pressure of the vapour distribution box is kept constant. Importantly, the combination of these two models allowed the PVD coating process to be simulated through the transition to the continuum Knudsen regime.
Gestión y medición del capital intelectual (activos intangibles) en las organizaciones
Authors: Aduna Lira Enrique
Published: March 2022

El presente estudio se centra en la comprensión y medición del capital intelectual (CI), término que es alusivo a los activos intangibles en el campo de la gestión de las organizaciones. Involucra la descomposición de sus diferentes dimensiones que la integran, como son el capital humano, el capital estructural y el capital relacional. El tema se desarrolla con un abordaje de análisis cualitativo, basado en investigación documental de diversas fuentes consultadas, identificando las dimensiones, componentes y variables específicas que deben de ser contempladas en el contenido de un modelo de medición del CI (intangibles).

Los resultados que arroja este trabajo no solo son la comprensión de todo un marco teórico de referencia sobre el tema en cuestión y sus mecanismos de medición, que justifican la importancia y contribución que tienen esta clase de bienes intangibles en los impactos concretos que se pueden lograr, sino también se proponen en los resultados del estudio una serie de modelos o conceptualizaciones nuevas para la gestión y desarrollo del CI en las organizaciones. Estas propuestas buscan ser una aportación a la aplicación práctica del tema, pero que con sus respectivos alcances, como se mencionan en las conclusiones del trabajo, pueden llegar a convertirse en una aplicación automatizada (software) que facilite su medición cotidiana.
Extensor Pollicis Brevis Transfer to Extensor Pollicis Longus for Delay Spontaneous Ruptures: A Case Series and Functional Outcomes at One Year Follow Up
Authors: G Kastanis , P Kapsetakis , C Chaniotakis , I Stavrakakis , A Pantouvaki
Published: March 2022

Introduction: When Extensor Pollicis Longus (EPL) spontaneously ruptures, two major risk factors are present: rheumatoid arthritis and distal radius fracture. The gold standard treatment is the transfer of Extensor Indicis Proprius (EIP) to restore the functionality of the thumb. Utilization of Extensor Pollicis Brevis (EPB) was used initially, in patients with rheumatoid arthritis. The aim of this study is to ascertain if the EPB transfer technique is the most competent and efficient surgical method for rupture of EPL, analyzing functional outcomes, complications and final patient`s satisfaction. Material & Methods: Eighteen patients (14 female and 4 men) with an average age of 43 years old were introduced in this study. All cases reported no history of trauma. From the derived clinical history, 8 cases suffered from rheumatoid arthritis, 4 patients reported initial corticosteroid injection in radial side of wrist, one case was revised surgery and in rest cases the etiology was unknown. Radiographic investigation was normal in all cases, while magnetic resonance studies detect EPL ruptures. All patients were operated in a mean time of 3, 4 weeks (ranging from 2 to 6 weeks) after the diagnosis and in all cases the tendon applied was the EPB. After surgery all patients followed the same rehabilitation program. Results: The mean follow-up was 20,5 months (range from 15 months to 36 months). None of patients missed the last re-examination. Results were evaluated according to complications, range of motion of the thumb (elevation deficit, opposition distance, difference flexion-extension deficit), Quick Dash Score, EQ-5D-5L, and satisfaction of the patients. No intra-or extra-operative complications or re-ruptures were noted. At the final follow up the mean range of elevation deficit was0,7(from 0,5 to 1,5), opposition distance was 0,8(range from 0,5 to 1,8) and difference flexion-extension deficit was 1,6˚ (from 0˚ to 5˚). The Quick Dash score was 1.38 (varied from 0.0- 6.8) and the EQ-5D-5L was 92. Finally, the majority of patients appeared to be very satisfied (66,7%) or satisfied (27,8%). Conclusion: Extensor Pollicis Longus tendon spontaneously ruptures due to specific factors. Restore of thumb functionality is achieved only with tendon transfer technique and the use of Extensor Indicis Proprius tendon has been described as the gold standard. Extensor Pollicis Brevis tendon transfer is an alternative technique with significant advantages which preserves good functionality of the thumb and excellent patient satisfaction.