bluuebunny/crossref_metadata_2025 huggingface dataset:
Konvergál-e a születéskor várható élettartam Európában?
Authors: Kovács Katalin
Published: June 2017

A tanulmány a születéskor várható élettartamok alakulására vonatkozó elméleti megközelítések közül az úgynevezett klub-elméleteket ismerteti részletesen. Empirikus vizsgálódásában az WHO Európai régiójában élő férfiak és nők születéskor várható élettartamának 1971 és a 2010-es eleje közötti alakulását elemzi. A várható élettartam fejlődését olyan országokban is tekintetbe veszi, ahol csak rövidebb időszakra nézve álltak adatok rendelkezésre. A várható élettartamok alakulása szerint az országokat trend-elemzés segítségével csoportosítja. A női várható  élettartamokat illetően az országok három csoportba voltak sorolhatóak. A nyugat-európai, a kelet-európai és a kelet-közép-európai országcsoportok azonban nem különültek el egymástól olyan élesen, hogy elkülönült kluboknak tekinthessük őket. A férfiak esetében azonban az idők folyamán legalább négy országcsoport (nyugat-európai, kelet-európai, balti és közép-kelet-európai) különült el. Az utóbbi országcsoporton belül  a legtöbb jel arra utal, hogy a Csehország, Lengyelország és Horvátország alkotta, valamint a Bulgáriát, Romániát, Magyarországot és Szlovákiát magában foglaló csoportok is elkülönülőben vannak egymástól.
Nemzetközi vándormozgalom és kezelése Dél-Koreában
Authors: Koudela Pál
Published: June 2017

Dél-Korea nemzetfelfogása rányomja bélyegét a migrációval kapcsolatos politikájára a diaszpórával, a munkaerő-bevándorlással és az integrációval kapcsolatban egyaránt. Az elmúlt évtizedek demográfiai változásaira, a csökkenő termékenységre, az elöregedő korszerkezetre és a zsugorodó népességre, s a mindezekből fakadó gazdasági problémákra a kormány aktívan reagál. A közelmúltban ez a nemzetgazdasági tervezésben és a multikulturális programokban is megmutatkozott, habár a változások a központosított adminisztráció által és gyorsan zajlanak, mégis egy nyitottabb társadalom irányába mutatnak. Továbbra is meghatározó a migrációs politika gazdasági érdekeknek való alárendelése, ám az emberi-jogi szempontok itt is egyre jobban érvényesülnek. A Koreai Köztársaság jelentős változáson megy keresztül, a bevándorlás és az országban élő külföldiek számának növekedése számottevő, így az ország a tágabb kelet-ázsiai térségben geopolitikai és migrációs értelemben is köztes helyet vívott ki magának.
As políticas sociais e a democratização da educação: novas fronteiras entre público e privado
Authors: Oliveira Dalila , Ferreira Elisa
Published: June 2017

Este artigo objetiva contribuir com o debate sobre política social, especificamente aquela que trata da educação, no contexto do capitalismo atual. Consideramos que as políticas públicas de educação no Brasil estão sendo empreendidas, particularmente após a segunda metade da década de 1990, sob um movimento articulado de expansão-focalização. As reformas empreendidas no Estado a na administração pública constituíram novas fronteiras entre o público e o privado na relação Estado e sociedade, de modo que a função pública tem-se caracterizado cada vez mais com um caráter normativo, regulador e avaliador. As políticas sociais de caráter universal têm cedido espaço às políticas de cunho compensatório. Nesse sentido, o Estado tem buscado parcerias com a sociedade civil para gerir os problemas sociais sob o argumento de que se trata de fenômenos de responsabilidade social. Dentre essas parcerias, existem aquelas que se desenvolvem por meio da oferta privada de serviços públicos, cuja forma de financiamento nos remete à tradicional prática do Estado brasileiro de preservação do capitalismo por meio do incentivo à sua reprodução e legitimação. Palavras-chave: políticas sociais; educação; reforma do Estado; reforma Educacional.
A educação no contexto da “nova gestão pública”
Authors: Scaff Elisângela
Published: June 2017

Este artigo propõe-se a discutir os princípios da “Nova gestão pública”, analisando seu impacto na política social brasileira, particularmente no que se refere à educação. Observa-se que essa tendência tem sido inserida na educação brasileira por meio não só da reforma administrativa do Estado, que se reflete em toda a sua política educacional, como também por meio de programas desenvolvidos a partir de acordos de cooperação internacional. Esses acordos vêm sendo ampliados na década de 1990, atingindo todas as regiões do país, inserindo nas escolas uma nova cultura organizacional, baseada na racionalidade técnica e no controle do trabalho escolar. Palavras-chave: cooperação internacional; gestão educacional; reforma educacional.
A etnomatemática, a matemática e a história na formação do professor de matemática
Authors: Fantinato Maria Cecília , Dias Ana Isabel , Rezende Wanderley
Published: June 2017

O artigo aborda o tema da formação do professor de matemática sob três enfoques diferentes e complementares. Inicia trazendo o potencial de uma formação na perspectiva Etnomatemática, que leva em conta os saberes dos educandos. Em seguida, são apresentados argumentos a favor de um estudo de história da matemática na formação do professor de matemática. Ao final, discutem-se quais tópicos da Matemática são indispensáveis na formação inicial do professor de matemática. Palavras-chave: formação de professores de matemática; etnomatemática; história da matemática.
Bullous aplasia cutis congenita: A report of two cases and brief review of the selected literature
Authors: Prcic Sonja , Matic Aleksandra , Jablanovic Sladjana , Matic Milan , Gajinov Zorica , Stasuk Natasa
Published: June 2017

Introduction. Aplasia cutis congenita (ACC) is a rare condition characterized by the focal absence of skin, and sometimes other underlying structures at birth. It may occur as an isolated defect or associated with other anomalies and defects. Bullous ACC (BACC) is a clinical subtype of the condition with few cases reported in the literature. It presents as a bullous lesion at birth which gradually transforms into an atrophic scar covered by a thin epithelial membrane. It is considered as cutaneous sign of possible neural tube dysraphism. Some cases present with a dark hair around the lesion (the hair collar sign), which can be even more indicative of neural tube defect. However, cases of BACC reported till today are inconclusive regarding this connection. Case report. We report a two cases of BACC of the scalp, in one patient associated with hair collar sign without neural tube defects and the other with hemangioma and we give a brief review of the selected literature. Conclusion. Bullous or membranous aplasia cutis congenita is benign condition, but may represent as a cutaneous marker of occult neural tube defect. Recognising the condition is important in order to rule out associated anomalies.
Relation between resilience and cigarette/alcohol use in adolescents with mild intellectual disability
Authors: Pavlovic Miroslav , Zunic-Pavlovic Vesna , Glumbic Nenad
Published: June 2017

Background/Aim. Resilience is related to the substance use in adolescence. However, little is known about the nature of this relation in adolescents with intellectual disability (ID). The aim of this research was to determine the relation among three domains of resilience (sense of mastery, sense of relatedness and emotional reactivity) and the substance use (cigarettes, alcohol, and marijuana) in adolescents with ID. Methods. The sample consisted of 100 adolescents of both genders with mild ID and aged 13-20 years. The Resiliency Scales for Children and Adolescents were used to assess resilience. Results. In the adolescents with ID, resilience was significantly related to the use of cigarettes (?2 = 13.384; df = 3; p = 0.004), but not to the use of alcohol (?2 = 6.789; df =3; p > 0.05). Out of the three assessed domains of resilience, increased emotional reactivity was the only significant predictor of cigarette use. Conclusion. The obtained results suggest that emotional difficulties may increase the risk of cigarette use in adolescents with ID.
Translation to Serbian, cultural adaptation, reliability testing and validation of the questionnaire estimating the fear of injections
Authors: Aleksic Dejan , Milosavljevic Milos , Bukonjic Andriana , Milovanovic Jasmina , Protrka Zoran , Radonjic Vesela , Jankovic Slobodan , Stefanovic Srdjan
Published: June 2017

Background/Aim. The two-part questionnaire called Injection Phobia Scale (IPS)-Anxiety and IPS-Avoidance represents one of the most commonly used questionnaires for assessing the fear of injections. The aim of the present study was to translate and culturally adapt this questionnaire from English into Serbian as well as to assess reliability and validity of the translation. Methods. The translation and cultural adaptation of the IPS?Anxiety and IPS?Avoidance was performed in accordance with the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) guidelines. Reliability testing, factor analysis and validation of Serbian translation of IPS-Anxiety and IPS-Avoidance were carried out on a sample of 485 students of pharmacy, or medicine at the University of Kragujevac, Serbia. Results. Serbian translation of IPS-Anxiety and IPSAvoidance demonstrated high internal consistency with Cronbach?s alpha of 0.934 for IPS-Anxiety and 0.911 for IPS-Avoidance. Factor analysis of IPS-Anxiety showed that there are two domains, which we have called as Direct Experience (9 items) and Indirect Experience (9 items); factor analysis of IPS-Avoidance also pointed out on two domains referring to direct and indirect fear of injections. Female students scored higher on the scale showing more extensive injection phobia than male students. It is also interesting that students of pharmacy have higher level of injection phobia than students of medicine, and those students of the fifth year of study feel more fear of injections than students from the first four years. Conclusion. Serbian translation of IPS-Anxiety and IPS-Avoidance showed good psychometric properties on population consisted of students medicine and pharmacy.
La transparencia como objetivo del desarrollo sostenible. The Transparency as an objective the sustainable development
Authors: Gilli Juan José
Published: June 2017

El presente trabajo tiene por propósito precisar el significado de la transparencia en la gestión pública como una exigencia de carácter ético relacionada con la información que los agentes deben dar en el ámbito sus funciones, reconociendo al ciudadano como el dueño de la información que producen y guardan. La transparencia tiene un especial valor como herramienta para combatir la corrupción y, de esa forma, contribuir a la meta de lograr instituciones inclusivas y efectivas para el desarrollo sostenible como lo establece el objetivo 16 de la Agenda Global para el Desarrollo Sostenible. El desarrollo del trabajo precisará los conceptos de transparencia, de acceso a la información, y de gobierno abierto que, a partir del el uso de la tecnología de información y comunicación, abre los procesos del Gobierno y permite el acceso del público a la información. Se concluye que la transparencia en la gestión pública es ante todo una decisión política mediatizada por procedimientos que aseguren el acceso a la información para el control ciudadano y, de esaforma, dar sentido a los sistemas democráticos.

Palabras claves: Transparencia; Desarrollo sostenible; Gobierno abierto.
Enfermería y el ejercicio de la investigación
Authors: Editorial Comité
Published: June 2017

El ejercicio profesional de Enfermería nos enfrenta a numerosas responsabilidades, largas horas de trabajo, gran número de pacientes a nuestro cargo, entornos de trabajo exigentes, sumado a nuestras propias responsabilidades familiares y sociales. Sin embargo, como comunidad profesional, tenemos la responsabilidad de desarrollar investigación científica. Al mencionar “investigación”, por lo general encontramos entusiasmo, pero al dividir el trabajo, como señala Clark (1), una respuesta común es “…no tengo tiempo suficiente…”. En este contexto, somos conscientes que todo ejercicio profesional requiere del respaldo del quehacer científico. Prueba de ello es que la mayoría de países de Latinoamérica cuentan con revistas de Enfermería. En el Perú, la publicación en revistas debería ser el punto de término ideal para toda producción intelectual realizada en los estudios de posgrado y de investigadores particulares; sin embargo, la realidad dista mucho de ello. Por lo tanto, el gran desafío que tenemos es reducir esta brecha y, para ello, empecemos por romper ciertos mitos.
Gisela Espinosa Damián y Ana Lau Jaiven, coords., Un fantasma recorre el siglo. Luchas feministas en México 1910-2010, México, Universidad Autónoma Metropolitana, Itaca, Conacyt, Ecosur, 2011, 546 p.
Authors: Rodríguez Bravo Roxana
Published: June 2017

El libro que se reseña a continuación es coordinado por Ana Lau Jaiven y Gisela Espinosa. Como el título indica, aborda las luchas feministas desde la Revolución mexicana de 1910.
Las complejas tramas de la educación escolar indígena en Brasil: discursos de interculturalidad y apropiaciones indígenas de la escuela
Authors: Paladino Mariana
Published: June 2017

El artículo presenta una discusión acerca de la interculturalidad en la educación escolar indígena en Brasil y analiza, a partir de tres ejemplos etnográficos, la complejidad de las representaciones y prácticas de los pueblos indígenas en relación con la institución escolar. Se pretende así cuestionar los discursos oficiales y las políticas indigenistas que aún se rigen por una visión esencializada de estos pueblos, sin respetar y atender sus demandas y realidades diferenciadas.
La educación intercultural y bilingüe (EIB) en México. ¿El camino hacia la construcción de una ciudadanía democrática?
Authors: Martínez Buenabad Elizabeth
Published: June 2017

El presente trabajo gira en torno a las políticas del lenguaje y educativas en México en distintos periodos, también a las reformas legales y jurídicas en aras de impartir mejores derechos y servicios a los ciudadanos. Sin embargo, a lo largo del documento revisaremos que estas medidas no serán suficientes si en verdad el Estado nacional pretende construir una sociedad intercultural e incluyente.
Crítica, desde la historia, a la reconstrucción lingüística diacrónica
Authors: De la Cruz Víctor
Published: June 2017

En este artículo el autor, desde la historia y la lógica, critica la reconstrucción lingüística fonológica de hipotéticas protolenguas. En el caso de las lenguas zapotecanas, la crítica parte de los errores cometidos por varios lingüistas en la reconstrucción del protozapoteco, en donde dos lingüistas en particular llegan a excesos especulativos para negar, mediante su hipótesis reconstructiva, la pre- sencia documentada de un fonema en las lenguas contemporáneas de la familia zapotecana.
DIREITOS HUMANOS: INTEGRAÇÃO E COMPLEMENTAÇÃO DOS DISPOSITIVOS NORMATIVOS DO DIREITO BRASILEIRO
Authors: Hasse Dorita Ziemann , Gouveia Tatiane Cristina
Published: June 2017

O presente trabalho tem como finalidade apresentar a importância da proteção dos direitos humanos tanto no âmbito interno, como no âmbito internacional; a evolução histórica dos direitos humanos, tendo como escopo fundamental o valor da dignidade pessoa humana como um dos princípios orientadores do ordenamento jurídico que contribuiu para o processo de internacionalização dos direitos humanos. Demonstrar a recepção dada aos direitos humanos pela Constituição Federal de 1988 no qual ensejou no processo de redemocratização do Brasil, rompendo a concepção de soberania estatal absoluta e reconhece a existência de limites ao poder do Estado. Busca-se também, analisar a interação entre o sistema jurídico interno e o direito internacional de direitos humanos juntamente com as inovações trazidas pela Emenda Constitucional n° 45 de 2004 que iniciou a chamada "Reforma do Poder Judiciário" objetivando esclarecer e produzir maior segurança jurídica, inserindo o § 3º, ao artigo 5º da Constituição da Constituição da República Federativa do Brasil.
AÇÕES AFIRMATIVAS E AS COTAS RACIAIS: SERÁ MESMO ESSE O CAMINHO?
Authors: Bertolazo Ivana Nobre , Ferreira Paulo Henrique de Campos Lopes
Published: June 2017

O presente trabalho tem por objetivo analisar em um caso concreto o Sistema de Cotas Raciais adotados no Brasil, sob o prisma do princípio da isonomia e da Dignidade da Pessoa Humana, demonstrando assim, o completo tratamento desigual criado por tal sistema, bem como a divisão do Brasil em raças. Será demonstrado ainda, a precariedade e a falta de fiscalização, bem como a omissão da Lei que regulamentou as Cotas Raciais, que tem como único critério a autodeclaração do candidato. Ainda, serão abordados todos os argumentos e fundamentos utilizados pelas partes no presente estudo de caso. Por fim, será discutido sobre a real eficácia do Sistema de Cotas Raciais, se realmente alcançando o fim para o qual foi criada.
TUNISIAN WOMEN, AT THE VANGUARD OF RESISTANCE
Authors: Oumhani Cécile
Published: June 2017

Essay
La movilización de las mujeres palestinas: de los anales a la “Rebelión de las piedras”
Authors: López Alberto Benjamín
Published: June 2017

El movimiento asociativo de mujeres palestinas tuvo su origen a finales del siglo XIX. Desde su configuración, su principal propósito ha sido el empoderamiento de la mujer palestina y la lucha contra la colonización sionista. En el siguiente artículo recogeremos sus principales exponentes así como la evolución de sus actividades.
Nahui Olin: Una mirada lúcida
Authors: Luque Rocío
Published: June 2017

Resumen: Nahui Olin, una de las artistas más versátiles y más bellas del México de los años veinte, tras un periodo fecundo de producción poética y pictórica, sufrió una progresiva etapa de marginación, en la que acabó por ser tildada simplemente como “loca”. En este estudio, a través del análisis de la palabra “locura” en el sentido filosófico del término, observamos cómo Nahui compartió en efecto todos los aspectos de este fenómeno, mostrando en realidad, sobre todo en Óptica cerebral, una mirada acerca de la concepción de sí misma, de la condición femenina y de la creación intelectual, sumamente lúcida. Nahui Olin: A lucid gaze Abstract: Nahui Olin, one of the most versatile and beautiful artists of Mexico’s twenties, after a fruitful period of poetic and pictorial production, suffered a progressive stage of marginalization, in which she will be branded simply as “crazy”. In this study, through the analysis of the word “madness” in the philosophical sense, we see how Nahui indeed shared all aspects of this phenomenon, showing reality, especially in Óptica cerebral, a gaze about the conception of oneself, the status of women and intellectual creation, extremely lucid.
Entrevista a Rossana Campo
Authors: García Valdés Pablo
Published: June 2017

Entrevista a Rossana Campo
Editors’ Introduction
Authors: Jones Stefanie A , Laine Eero
Published: June 2017

This issue of Lateral examines the means by which performances happen at a variety of scales of cultural production and circulation, from the street to the living room to the border; from a cellphone to the theatrical stage to the art gallery; from public discourse in policy debates to the global circulation of performances of blackness, alterity, and power. Trends across these various means are thus particularly illuminating for the study of culture; performance can give us insight into aspects of culture more broadly and with great ability to account for differences and dynamics of power.
Response to Tanja Aho and Leland Tabares: Madness and Parainstitutionality
Authors: Melamed Jodi
Published: June 2017

Response to Tanja Aho and Leland Tabares on original essay by Jodi Melamed, "Proceduralism, Predisposing, Poesis: Forms of Institutionality," In the Making, published in Lateral 5.1.
Target Markets and Logistical Management
Authors: Weinberg Lindsay
Published: June 2017

Critical studies on logistics and supply chain management often focus on the transformations in the organization of labor that result from an emphasis on the circulation of commodities. However, target marketing and practices of leisure-time surveillance are not generally framed as part of the shift in capital’s emphasis on circulation. If part of logistical management is about the displacement of labor to the underdeveloped world, it is equally about monitoring circulation and demand in the overdeveloped. This paper argues that situating target marketing as a technology of logistical management emphasizes the importance of information in not only intensifying and maximizing the productivity of supply chains and reducing labor costs but also increasing the likelihood of a return on capitalist investment through the management of market choices. The paper begins by framing target marketing as part of the historical trajectory of the revolution in control described by James R. Beniger. I then demonstrate how target marketing provides valuable point-of-sale and point-of-interaction insights, and platform providers can wield this information to control prices and allocate advertisements as well as manage distribution and arbitrage the labor market. Rather than conceptualizing the production of user data as a form of labor in the context of target marketing, I argue that the labor theory of value is untenable for understanding the conditions of leisure-time surveillance and data aggregation. The category of labor is useful in that it highlights the exploitation of user data, but it tends to collapse distinctions between the workday and leisure-time in ways that mystify the differences in how capitalism exercises control over subjects. I then provide a close reading of an Amazon affiliated fulfillment center expose in order to examine precisely how the information produced during leisure-time surveillance intensifies the exploitation of fulfillment center labor. Target marketing is part of a larger apparatus that aggregates data for the purposes of assigning risk, differentiating prices, and managing supply chains and labor costs. It equally reinforces biases and discriminatory practices prevalent in financial institutions in order to maximize profit through the aggregation of data produced by users during seemingly innocuous acts of consumption and online attentiveness.
Osteoarthritis Management: Time to Change the Deck
Authors: Hunter David J.
Published: June 2017

This Viewpoint highlights the shortcomings of existing osteoarthritis (OA) clinical practices and emphasizes the opportunity that can come about by virtue of adherence to appropriate management. In an effort to emphasize optimism, there are huge missed opportunities with existing efficacious treatments and tremendous developments that are currently going on that will positively influence future care. How we respond to that opportunity will not only impact the individuals disabled by the disease but also make a massive difference to our society through reducing underemployment and health care waste.

J Orthop Sports Phys Ther 2017;47(6):370–372. doi:10.2519/jospt.2017.0605
The principles of measurement and testing to characterize material properties
Authors: Czichos Horst
Published: June 2017

This contribution describes the principles of measurement and testing, and a combined measurement testing methodology to characterize material properties.
Flow diversion of tandem cerebral aneurysms: a multi-institutional retrospective study
Authors: Awad Al-Wala , Moon Karam , Yoon Nam , Mazur Marcus D. , Kalani M. Yashar S. , Taussky Philipp , McDougall Cameron G. , Albuquerque Felipe C. , Park Min S.
Published: June 2017

OBJECTIVE

Flow diversion has proven to be an efficacious means of treating cerebral aneurysms that are refractory to other therapeutic means. Patients with tandem aneurysms treated with flow diversion have been included in larger, previously reported series; however, there are no dedicated reports on using this technique during a single session to treat this unique subset of patients. Therefore, the authors analyzed the outcomes of patients who had undergone single-session flow diversion for the treatment of tandem aneurysms.

METHODS

The authors conducted a retrospective review of flow diversion with the Pipeline embolization device (PED) for the treatment of tandem aneurysms in a single session at 2 participating medical centers: University of Utah, Salt Lake City, Utah, and Barrow Neurological Institute, Phoenix, Arizona. Patient demographic data, aneurysm characteristics, treatment strategy and results, complications, and follow-up data were collected from the medical record and analyzed.

RESULTS

Between January 2011 and December 2015, 17 patients (12 female, 5 male) with a total of 38 aneurysms (mean size 4.7 ± 2.7 mm, mean ± SD) were treated. Sixteen patients had aneurysms in the anterior circulation, and 1 patient had tandem aneurysms in the posterior circulation. Twelve patients underwent only placement of a PED, whereas 5 underwent adjunctive coil embolization of at least 1 aneurysm. One PED was used in each of 9 patients, and 2 PEDs were required in each of 8 patients. There were 2 intraprocedural complications; however, in both instances, the patients were asymptomatic at the last follow-up. The follow-up imaging studies were available for 15 patients at a mean of 7 months after treatment (216 days, range 0–540 days). The mean initial Raymond score after treatment was 2.7 ± 0.7, and the mean final score was 1.3 ± 0.7.

CONCLUSIONS

In this series, the use of flow diversion for the treatment of tandem cerebral aneurysms had an acceptable safety profile, indicating that it should be considered as an effective therapy for this complicated subset of patients. Further prospective studies must be performed before more definitive conclusions can be made.
Postprocedural, midterm, and long-term results of cerebral aneurysms treated with flow-diverter devices: 7-year experience at a single center
Authors: Briganti Francesco , Leone Giuseppe , Cirillo Luigi , de Divitiis Oreste , Solari Domenico , Cappabianca Paolo
Published: June 2017

OBJECTIVE

Flow diversion has emerged as a viable treatment option for selected intracranial aneurysms and recently has been gaining traction. The aim of this study was to evaluate the safety and effectiveness of flow-diverter devices (FDDs) over a long-term follow-up period.

METHODS

The authors retrospectively reviewed all cerebral aneurysm cases that had been admitted to the Division of Neurosurgery of the Università degli Studi di Napoli between November 2008 and November 2015 and treated with an FDD. The records of 60 patients (48 females and 12 males) harboring 69 cerebral aneurysms were analyzed. The study end points were angiographic evidence of complete aneurysm occlusion, recanalization rate, occlusion of the parent artery, and clinical and radiological evidence of brain ischemia. The occlusion rate was evaluated according to the O’Kelly-Marotta (OKM) Scale for flow diversion, based on the degree of filling (A, total filling; B, subtotal filling; C, entry remnant; D, no filling). Postprocedural, midterm, and long-term results were strictly analyzed.

RESULTS

Complete occlusion (OKM D) was achieved in 63 (91%) of 69 aneurysms, partial occlusion (OKM C) in 4 (6%), occlusion of the parent artery in 2 (3%). Intraprocedural technical complications occurred in 3 patients (5%). Postprocedural complications occurred in 6 patients (10%), without neurological deficits. At the 12-month follow-up, 3 patients (5%) experienced asymptomatic cerebral infarction. No further complications were observed at later follow-up evaluations (> 24 months). There were no reports of any delayed aneurysm rupture, subarachnoid or intraparenchymal hemorrhage, ischemic complications, or procedure- or device-related deaths.

CONCLUSIONS

Endovascular treatment with an FDD is a safe treatment for unruptured cerebral aneurysms, resulting in a high rate of occlusion. In the present study, the authors observed effective and stable aneurysm occlusion, even at the long-term follow-up. Data in this study also suggest that ischemic complications can occur at a later stage, particularly at 12–18 months. On the other hand, no other ischemic or hemorrhagic complications occurred beyond 24 months.
Use of the Pipeline embolization device in the treatment of iatrogenic intracranial vascular injuries: a bi-institutional experience
Authors: Griauzde Julius , Ravindra Vijay M. , Chaudhary Neeraj , Gemmete Joseph J. , Mazur Marcus D. , Roark Christopher D. , Couldwell William T. , Park Min S. , Taussky Philipp , Pandey Aditya S.
Published: June 2017

OBJECTIVE

Flow-diverting devices have been used for the treatment of complex intracranial vascular pathology with success, but the role of these devices in treating iatrogenic intracranial vascular injuries has yet to be clearly defined. Here, the authors report their bi-institutional experience with the use of the Pipeline embolization device (PED) for the treatment of iatrogenic intracranial vascular injuries.

METHODS

The authors reviewed a retrospective cohort of patients with iatrogenic injuries to the intracranial vasculature that were treated with the PED between 2012 and 2016. Data collection included demographic data, indications for treatment, number and sizes of PEDs used, and immediate and follow-up angiographic and clinical outcomes.

RESULTS

Four patients with a mean age of 47.5 years (range 18–63 years) underwent PED placement for iatrogenic vessel injuries. In 3 patients, the intracranial internal carotid artery (ICA) was injured during transnasal tumor resection. In 1 patient, a basilar apex injury occurred during endoscopic third ventriculostomy. Three patients had a pseudoaneurysm as a result of vessel injury, and 1 patient had frank ICA laceration and extravasation. All 3 pseudoaneurysms were successfully treated with PED deployment. The ICA laceration was refractory to PED placement, and the vessel was subsequently occluded endovascularly. All 4 patients had a good clinical outcome (modified Rankin Scale score of 0 or 1).

CONCLUSIONS

The use of the PED is feasible in the management of iatrogenic pseudoaneurysms of the intracranial vasculature. In cases of frank vessel perforation, an alternative strategy such as covered stent placement should be considered. Endovascular or surgical vessel occlusion remains the definitive treatment in cases of refractory hemorrhage.
Prolapse of the Pipeline embolization device in aneurysms: incidence, management, and outcomes
Authors: Srinivasan Visish M. , Carlson Andrew P. , Mokin Maxim , Cherian Jacob , Chen Stephen R. , Puri Ajit , Kan Peter
Published: June 2017

OBJECTIVE

The Pipeline embolization device (PED) is frequently used in the treatment of anterior circulation aneurysms, especially around the carotid siphon, with generally excellent results. However, the PED has its own unique technical challenges, including the occurrence of device foreshortening or migration leading to prolapse into the aneurysm. The authors sought to determine the incidence of this phenomenon, the rescue strategies, and outcomes.

METHODS

Four institutional databases of neuroendovascular procedures were reviewed for cases of intracranial aneurysms treated with PEDs. Patient and aneurysm data as well as angiographic imaging were reviewed for all cases involving device prolapse into the aneurysm.

RESULTS

A total of 413 intracranial aneurysms were treated with PEDs during the study period, by 5 neurointerventionalists. Large and giant aneurysms (≥ 2 cm) accounted for 32 of these aneurysms. Among these 32 PEDs, prolapse into the aneurysm occurred in 3 patients, with 1 of these PEDs successfully rescued and the other 2 left in situ. No patients suffered any severe complications. The 2 patients in whom the PEDs were left in situ remained on antiplatelet therapy.

CONCLUSIONS

The PED may foreshorten or migrate during or after deployment, leading to prolapse into the aneurysm. This phenomenon appears to be associated with large and giant aneurysms, vessel tortuosity, short landing zones, and use of balloon angioplasty. Future study and follow-up is needed to further evaluate this phenomenon, but some of the observations and techniques described in this paper may help to prevent or salvage prolapsed devices.
Pipeline embolization device for recurrence of previously treated aneurysms
Authors: Dornbos David , Karras Constantine L. , Wenger Nicole , Priddy Blake , Youssef Patrick , Nimjee Shahid M. , Powers Ciarán J.
Published: June 2017

OBJECTIVE

The utilization of the Pipeline embolization device (PED) has increased significantly since its inception and original approval for use in large, broad-necked aneurysms of the internal carotid artery. While microsurgical clipping and advances in endovascular techniques have improved overall efficacy in achieving complete occlusion, recurrences still occur, and the best modality for retreatment remains controversial. Despite its efficacy in this setting, the role of PED utilization in the setting of recurrent aneurysms has not yet been well defined. This study was designed to assess the safety and efficacy of PED in the recurrence of previously treated aneurysms.

METHODS

The authors reviewed a total of 13 cases in which patients underwent secondary placement of a PED for aneurysm recurrence following prior treatment with another modality. The PEDs were used to treat aneurysm recurrence or residual following endovascular coiling in 7 cases, flow diversion in 2, and microsurgical clipping in 4. The mean time between initial treatment and retreatment with a PED was 28.1 months, 12 months, and 88.7 months, respectively. Clinical outcomes, including complications and modified Rankin Scale (mRS) scores, and angiographic evidence of complete occlusion were tabulated for each treatment group.

RESULTS

All PEDs were successfully placed without periprocedural complications. The rate of complete occlusion was 80% at 6 months after PED placement and 100% at 12 months in these patients who underwent PED placement following failed endovascular coiling; there were no adverse clinical sequelae at a mean follow-up of 26.1 months. In the 2 cases in which PEDs were placed for treatment of residual aneurysms following prior flow diversion, 1 patient demonstrated asymptomatic vessel occlusion at 6 months, and the other exhibited complete aneurysm occlusion at 12 months. In patients with aneurysm recurrence following prior microsurgical clipping, the rate of complete occlusion was 100% at 6 and 12 months, with no adverse sequelae noted at a mean clinical follow-up of 27.7 months.

CONCLUSIONS

The treatment of recurrent aneurysms with the PED following previous endovascular coiling, flow diversion, or microsurgical clipping is associated with a high rate of complete occlusion and minimal morbidity.
Endovascular management of fusiform aneurysms in the posterior circulation: the era of flow diversion
Authors: Awad Ahmed J. , Mascitelli Justin R. , Haroun Reham R. , De Leacy Reade A. , Fifi Johanna T. , Mocco J
Published: June 2017

Fusiform aneurysms are uncommon compared with their saccular counterparts, yet they remain very challenging to treat and are associated with high rates of rebleeding and morbidity. Lack of a true aneurysm neck renders simple clip reconstruction or coil embolization usually impossible, and more advanced techniques are required, including bypass, stent-assisted coiling, and, more recently, flow diversion. In this article, the authors review posterior circulation fusiform aneurysms, including pathogenesis, natural history, and endovascular treatment, including the role of flow diversion. In addition, the authors propose an algorithm for treatment based on their practice.
Pipeline flow diversion of ruptured blister aneurysms of the supraclinoid carotid artery using a single-device strategy
Authors: Ryan Robert W. , Khan Amir S. , Barco Rebecca , Choulakian Armen
Published: June 2017

OBJECTIVE

Ruptured blister aneurysms remain challenging lesions for treatment due to their broad, shallow anatomy and thin, fragile wall. Historical challenges with both open microsurgical approaches and intrasaccular endovascular approaches have led to increased use of flow diversion for management of these aneurysms. However, the optimum paradigm, including timing of treatment, use of dual antiplatelet therapy, and number of flow-diverter devices to use remains unknown. The authors describe their experience with ruptured blister aneurysms treated with flow diversion at their institution, and discuss rates of rebleeding and number of devices used.

METHODS

All patients presenting with subarachnoid hemorrhage from a ruptured blister aneurysm and treated with Pipeline flow diversion were identified. Patient demographic data, clinical status and course, need for external ventricular drain (EVD), timing of treatment, and angiographic details and follow-up were recorded.

RESULTS

There were 13 patients identified (11 women and 2 men), and 4 had multiple aneurysms. Two aneurysms were treated on initial angiography, with average time to treatment of 3.1 days for the remainder, after discussion with the family and institution of dual antiplatelet therapy. Device placement was technically successful in all patients, with 2 patients receiving 2 devices and the remainder receiving 1 device. There was 1 intraoperative complication, of a wire perforation causing intracerebral hemorrhage requiring decompressive craniectomy. Three patients had required EVD placement for management of hydrocephalus. There was no rebleeding from the target lesion; however, one patient had worsening intraventricular hemorrhage and another had rupture of an unrecognized additional aneurysm, and both died. Of the other 11 patients, 10 made a good recovery, with 1 remaining in a vegetative state. Nine underwent follow-up angiography, with 5 achieving complete occlusion, 2 with reduced aneurysm size, and 2 requiring retreatment for aneurysm persistence or enlargement. There were no episodes of delayed rupture.

CONCLUSIONS

Pipeline flow diversion is a technically feasible and effective treatment for ruptured blister aneurysms, particularly in good-grade patients without hydrocephalus. Patients with a worse grade on presentation and requiring EVDs may have higher risk for bleeding complications and poor outcome. There was no rebleeding from the target lesion with use of a single device in this series.
Bifunctional Enzyme JMJD6 Contributes to Multiple Disease Pathogenesis: New Twist on the Old Story
Authors: Vangimalla Shiva Shankar , Ganesan Murali , Kharbanda Kusum K. , Osna Natalia A.
Published: June 2017

Jumonji domain-containing protein 6 (JMJD6) is a non-heme Fe(II) 2-oxoglutarate (2OG)-dependent oxygenase with arginine demethylase and lysyl hydroxylase activities. Its initial discovery as a dispensable phosphatidylserine receptor (PSR) in the cell membrane of macrophages for phagocytosis was squashed by newer studies which revealed its nuclear localization and bifunctional enzymatic activity. Though its interaction with several nuclear and cytoplasmic target proteins has been demonstrated, the exact mechanisms and clinical significance of these various biologic interplays are not yet well established. Recent investigations have shed the light on the multiple pathways by which JMJD6 can regulate cell proliferation and cause tumorigenesis. Clinically, JMJD6 has been associated with more aggressive and metastatic disease, poorer prognosis, and lower overall survival rates—particularly in lung colon and oral cancers. JMJD6 is a novel biomarker for predicting future disease outcomes and is a target for new therapeutic treatments in future studies. Aberrant expression and dysregulation of JMJD6 are implicated in various other processes such as impaired T-cell proliferation and maturation, inoculation, and virulence of foot-and-mouth disease virus (FMDV), and impaired methylation of innate immunity factor. This article reviews the association of JMJD6 with various pathological processes—particularly, its role in tumorigenesis and virological interactions.
Anti-Skin-Aging Activity of a Standardized Extract from Panax ginseng Leaves In Vitro and In Human Volunteer
Authors: Shin Seoungwoo , Lee Jung-A , Son Dahee , Park Deokhoon , Jung Eunsun
Published: June 2017

Ginseng leaves contain high saponin composition and content, but are used less often than the root part. To develop a use for the leaves that exploits their properties, we studied ginseng leaves as the raw material of anti-aging cosmetics. This study highlights an assessment of the cellular factivity and clinical efficacy of ginseng leaf extract, providing necessary information relevant to the development of new cosmetic products. Panax ginseng leaf purified extracts (PGLE) were shown to have high contents of Rb3 and Rb2. Rb3, the major chemical components of PGLE, promoted collagen synthesis though the activation of transforming growth factor-β (TGF-β) in human skin fibroblast cells. In addition, the possibility of PGLE as an anti-skin-aging agent has also been clinically validated. Our analysis of the crow’s feet wrinkle showed that there was a decrease in the depth of deep furrows in the region of interest (RI) treated with PGLE lotion over an eight-week period. Based on these results, we suggest the possibility that PGLE, having high levels of Rb3, be considered as an attractive, wrinkle-reducing candidate for topical application.
Comparative Energy Performance Analysis of Six Primary Photovoltaic Technologies in Madrid (Spain)
Authors: Adrada Guerra Teodoro , Amador Guerra Julio , Orfao Tabernero Beatriz , De la Cruz García Guillermo
Published: June 2017

There are a wealth of studies on photovoltaic cell technologies, however their performance in different climatic or geographies over an extended period is not completely established. The objective of this paper is to add to this area of study with an analysis of the principle photovoltaic technologies: monocrystalline silicon (mc-Si), polycrystalline silicon (pc-Si), tandem structure of amorphous silicon and microcrystalline silicon (a-Si/µc-Si tandem), cadmium telluride/cadmium sulfide (CdTe/CdS), copper-indium diselenide (CIS) and monocrystalline silicon with double contact back technology (mc-dc-Si), in the climatic conditions particular to the middle latitude urban environment of Madrid (Spain). To carry out this study six photovoltaic subsystems of peak power 1 kWp approximately have been installed for each selected technology on the roof of the Escuela Técnica Superior de Ingeniería y Diseño Industrial (ETSIDI) of the Universidad Politécnica de Madrid (UPM) in Spain. Each subsystem has an inverter of the same model and power for its connection to the internal electricity network of the university. This paper analyzes the energy performance of the six subsystems, calculating the reference production rates and losses, from February 2013 to December 2015. The result of the study is the extensive capture of data and detailed analysis of real time energy yields and performance ratios of key technologies resulting with patterns in line with those of other regions with comparable climatic conditions.
Socioeconomic Disparity in Later-Year Group Trajectories of Depressive Symptoms: Role of Health and Social Engagement Change
Authors: Lee Hyunjoo , Park Sojung , Kwon Eunsun , Cho Joonyoung
Published: June 2017

This study explored heterogeneous change patterns of South Korean older adults’ depressive symptoms by poverty status, focusing on health status and social engagement changes. We used data from four waves (2006–2012) of the Korean Longitudinal Study of Aging (KLoSA). Our sample contained 2461 poor and 1668 non-poor individuals. All were 65 years old or older at baseline. We used latent class growth analysis to identify trajectory groups’ depressive symptoms. Multinomial logistic regression was used to examine how a range of changes in health conditions and social engagement was associated with trajectories among poor and non-poor participants. Among the poor, five heterogeneous trajectories with clear patterns were identified: high-to-moderate, stable-high, slightly-increasing, steeply-increasing, and stable-low. Among non-poor, high-to-moderate, steeply-increasing, and stable-low groups were found. A decrease in health conditions was the most vulnerable subgroup’s (steeply-increasing) primary risk factor. Poor older adults who reduced participation in, or decreased contact with, social networks were likely to belong to the steeply-increasing group. Our study provides impetus for organizational and/or environmental support systems to facilitate social engagement among poor older adults. Future research should examine whether the significance of social engagement among poor elders applies in less-developed and developed countries.
A Multiple Ant Colony Optimization Algorithm for Indoor Room Optimal Spatial Allocation
Authors: Yang Lina , Sun Xu , Zhu Axing , Chi Tianhe
Published: June 2017

Indoor room optimal allocation is of great importance in geographic information science (GIS) applications because it can generate effective indoor spatial patterns that improve human behavior and efficiency. However, few research concerning indoor room optimal allocation has been reported. Using an office building as an example, this paper presents an integrative approach for indoor room optimal allocation, which includes an indoor room allocation optimization model, indoor connective map design, and a multiple ant colony optimization (MACO) algorithm. The mathematical optimization model is a minimized model that integrates three types of area-weighted costs while considering the minimal requirements of each department to be allocated. The indoor connective map, which is an essential data input, is abstracted by all floor plan space partitions and connectivity between every two adjacent floors. A MACO algorithm coupled with three strategies, namely, (1) heuristic information, (2) two-colony rules, and (3) local search, is effective in achieving a feasible solution of satisfactory quality within a reasonable computation time. A case study was conducted to validate the proposed approach. The results show that the MACO algorithm with these three strategies outperforms other types of ant colony optimization (ACO), Genetic Algorithm (GA), and particle swarm optimization (PSO) algorithms in quality and stability, which demonstrates that the proposed approach is an effective technique for generating optimal indoor room spatial patterns.
Crystallization of Jarosite with Variable Al3+ Content: The Transition to Alunite
Authors: Jones Franca
Published: June 2017

This study focused on the formation of the jarosite-alunite solid solution at relatively low temperature, 90 °C. It was found that the transition from jarosite to alunite results in significant changes in the powder X-ray diffraction pattern, the infrared spectrum and thermal behavior when the degree of substitution reached ≥50%. The initial Al/(Al + Fe) in solution, however, required to achieve these substitution levels in the solid is ≥90%. The morphology shows that the faceted jarosite form goes through an intergrown transition to a spherical morphology of pure alunite. This morphology has not been previously observed for alunite and most likely reflects the formation temperature. Rietveld analysis shows that the a lattice parameter obeys Vegard’s Rule while the c lattice parameter behavior is more complex. Empirical modelling of the incorporation of Fe into alunite supports the general trends found in the X-ray diffraction data for the behaviour of the a-axis with Al/Fe content. The dehydration of the Al3+ ion could be a significant contribution to the activation energy barrier to alunite formation as found for other minerals. Finally, dynamic light scattering showed that the nucleation behavior for jarosite and Fe-containing alunite are significantly different. Alunite appears to nucleate continuously rather than in a single nucleation event.