bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of the share of wood filler and magnesite on the strength of composite
Authors: Sapunova Anastasiya , Titunin Andrey
Published: April 2024

Research in the field of creating new composite materials, including those based on magnesia binder and wood shavings – wood raw material - plays an important role in solving strategic tasks of construction complex development. Differences in the shape, size, and fractional composition of chips and wood shavings, which is used in the manufacture of the material-analogue (arbolite), determine the need to substantiate the composition of mixture main components. According the research, we obtained the relationship between the strength properties of wood-mineral composite (WMC) and the proportion of wood filler in the structure of the material. The study revealed relation of change in the compressive and bending strength indices of WMC with increasing mass content of wood shavings. It is recommended to maintain the ratio of wood shaving : magnesia binder at the level of 20 : 80, taking into account the intensity of strength properties change in the development of rational WMC composition.
Understanding the role of transmembrane 9 superfamily member 1 in bladder cancer pathogenesis
Authors: Gade Venkata Krishna Vamsi , Yadav Budhi Singh
Published: April 2024

In this editorial we comment on the article by Wei et al , published in the recent issue of the World Journal of Clinical Oncology . The authors investigated the role of Transmembrane 9 superfamily member 1 (TM9SF1) protein in bladder cancer (BC) carcinogenesis. Lentiviral vectors were used to achieve silencing or overexpression of TM9SF1 gene in three BC cell lines. These cell lines were then subject to cell counting kit 8, wound-healing assay, transwell assay, and flow cytometry. Proliferation, migration, and invasion of BC cells were increased in cell lines subjected to TM9SF1 overexpression. TM9SF1 silencing inhibited proliferation, migration and invasion of BC cells. The authors conclude that TM9SF1 may be an oncogene in bladder cancer pathogenesis.
Britanin – a beacon of hope against gastrointestinal tumors?
Authors: Kajdanek Agnieszka , Kołat Damian , Zhao Lin-Yong , Kciuk Mateusz , Pasieka Zbigniew , Kałuzińska-Kołat Żaneta
Published: April 2024

Britanin is a bioactive sesquiterpene lactone known for its potent anti-inflammatory and anti-oxidant properties. It also exhibits significant anti-tumor activity, suppressing tumor growth in vitro and in vivo . The current body of research on Britanin includes thirty papers predominantly related to neoplasms, the majority of which are gastrointestinal tumors that have not been summarized before. To drive academic debate, the present paper reviews the available research on Britanin in gastrointestinal tumors. It also outlines novel research directions using data not directly concerned with the digestive system, but which could be adopted in future gastrointestinal research. Britanin was found to counteract liver, colorectal, pancreatic, and gastric tumors, by regulating proliferation, apoptosis, autophagy, immune response, migration, and angiogenesis. As confirmed in pancreatic, gastric, and liver cancer, its most commonly noted molecular effects include nuclear factor kappa B and B-cell lymphoma 2 downregulation, as well as Bcl-2-associated X protein upregulation. Moreover, it has been found to induce the Akt kinase and Forkhead box O1 axis, activate the AMP-activated protein kinase pathway, elevate interleukin-2 and peroxisome proliferator-activated receptor-γ levels, reduce interleukin-10, as well as downregulate matrix metalloproteinase-9, Twist family bHLH transcription factor 1, and cyclooxygenase-2. It also inhibits Myc–HIF1α interaction and programmed death ligand 1 transcription by interrupting the Ras/ RAF/MEK/ERK pathway and mTOR/P70S6K/4EBP1 signaling. Future research should aim to unravel the link between Britanin and acetylcholinesterase, mast cells, osteolysis, and ischemia, as compelling data have been provided by studies outside the gastrointestinal context. Since the cytotoxicity of Britanin on noncancerous cells is significantly lower than that on tumor cells, while still being effective against the latter, further in-depth studies with the use of animal models are merited. The compound exhibits pleiotropic biological activity and offers considerable promise as an anti-cancer agent, which may address the current paucity of treatment options and high mortality rate among patients with gastrointestinal tumors.
Molecular targets and mechanisms of different aberrant alternative splicing in metastatic liver cancer
Authors: Geng De-Yi , Chen Qing-Shan , Chen Wan-Xian , Zhou Lin-Sa , Han Xiao-Sha , Xie Qi-Hu , Guo Geng-Hong , Chen Xue-Fen , Chen Jia-Sheng , Zhong Xiao-Ping
Published: April 2024

Metastasis remains a major challenge in the successful management of malignant diseases. The liver is a major site of metastatic disease and a leading cause of death from gastrointestinal malignancies such as colon, stomach, and pancreatic cancers, as well as melanoma, breast cancer, and sarcoma. As an important factor that influences the development of metastatic liver cancer, alternative splicing drives the diversity of RNA transcripts and protein subtypes, which may provide potential to broaden the target space. In particular, the dysfunction of splicing factors and abnormal expression of splicing variants are associated with the occurrence, progression, aggressiveness, and drug resistance of cancers caused by the selective splicing of specific genes. This review is the first to provide a detailed summary of the normal splicing process and alterations that occur during metastatic liver cancer. It will cover the role of alternative splicing in the mechanisms of metastatic liver cancer by examining splicing factor changes, abnormal splicing, and the contribution of hypoxia to these changes during metastasis.
Regulation of TMEM100 expression by epigenetic modification, effects on proliferation and invasion of esophageal squamous carcinoma
Authors: Xu Yue-Feng , Dang Yan , Kong Wei-Bo , Wang Han-Lin , Chen Xiu , Yao Long , Zhao Yuan , Zhang Ren-Quan
Published: April 2024

BACKGROUND

Esophageal squamous cell carcinoma (ESCC) is a prevalent malignancy with a high morbidity and mortality rate. TMEM100 has been shown to be suppressor gene in a variety of tumors, but there are no reports on the role of TMEM100 in esophageal cancer (EC).

AIM

To investigate epigenetic regulation of TMEM100 expression in ESCC and the effect of TMEM100 on ESCC proliferation and invasion.

METHODS

Firstly, we found the expression of TMEM100 in EC through The Cancer Genome Atlas database. The correlation between TMEM100 gene expression and the survival of patients with EC was further confirmed through Kaplan-Meier analysis. We then added the demethylating agent 5-AZA to ESCC cell lines to explore the regulation of TMEM100 expression by epigenetic modification. To observe the effect of TMEM100 expression on tumor proliferation and invasion by overexpressing TMEM100. Finally, we performed gene set enrichment analysis using the Kyoto Encyclopaedia of Genes and Genomes Orthology-Based Annotation System database to look for pathways that might be affected by TMEM100 and verified the effect of TMEM100 expression on the mitogen-activated protein kinases (MAPK) pathway.

RESULTS

In the present study, by bioinformatic analysis we found that TMEM100 was lowly expressed in EC patients compared to normal subjects. Kaplan-meier survival analysis showed that low expression of TMEM100 was associated with poor prognosis in patients with EC. Then, we found that the demethylating agent 5-AZA resulted in increased expression of TMEM100 in ESCC cells [quantitative real-time PCR (qRT-PCR) and western blotting]. Subsequently, we confirmed that overexpression of TMEM100 leads to its increased expression in ESCC cells (qRT-PCR and western blotting). Overexpression of TMEM100 also inhibited proliferation, invasion and migration of ESCC cells (cell counting kit-8 and clone formation assays). Next, by enrichment analysis, we found that the gene set was significantly enriched in the MAPK signaling pathway. The involvement of TMEM100 in the regulation of MAPK signaling pathway in ESCC cell was subsequently verified by western blotting.

CONCLUSION

TMEM100 is a suppressor gene in ESCC, and its low expression may lead to aberrant activation of the MAPK pathway. Promoter methylation may play a key role in regulating TMEM100 expression.
Low-grade myofibrosarcoma of the maxillary sinus: Two case reports
Authors: Mydlak Anna , Ścibik Łukasz , Durzynska Monika , Zwoliński Jakub , Buchajska Karolina , Lenartowicz Olga , Kucharz Jakub
Published: April 2024

BACKGROUND

Low-grade myofibroblastic sarcoma (LGMS) is an extremely rare tumor characterized by the malignant proliferation of myofibroblasts. LGMS most commonly develops in adults, predominantly in males, in the head and neck region, oral cavity, especially on the tongue, mandible, and larynx. This article presents 2 cases of LGMS localized to the maxillary sinus and provides an overview of the available literature.

CASE SUMMARY

Two patients with LGMS located in the maxillary sinus underwent surgery at the Department of Head and Neck Surgery. Case 1: A 46-year-old patient was admitted to the clinic with suspected LGMS recurrence in the right maxillary sinus (rT4aN0M0), with symptoms of pain in the suborbital area, watering of the right eye, thick discharge from the right nostril, and augmented facial asymmetry. After open biopsy-confirmed LGMS, the patient underwent expanded maxillectomy of the right side with immediate palate reconstruction using a microvascular skin flap harvested surgically from the middle arm. The patient qualified for adjuvant radiotherapy for the postoperative bed, with an additional margin. Currently, the patient is under 1.5 years of observation with no evidence of disease. Case 2: A 45-year-old man was admitted to our clinic with facial asymmetry, strabismus, exophthalmos, and visual impairment in the right eye. Six months earlier, the patient had undergone partial jaw resection at another hospital for fibromatosis. A contrast-enhanced computed tomography scan revealed a tumor mass in the postoperative log after an earlier procedure. An open biopsy confirmed low-grade fibrosarcoma (rT4aN0M0). The patient qualified for an extended total right maxillectomy with orbital excision and right hemimandibulectomy with immediate microvascular reconstruction using an anterolateral thigh flap. The patient subsequently underwent adjuvant radiotherapy to the postoperative area. After 9 months, recurrence occurred in the right mandibular arch below the irradiated area. The lesion infiltrated the base of the skull, which warranted the withdrawal of radiotherapy and salvage surgery. The patient qualified for palliative chemotherapy with a regimen of doxorubicin + dacarbazine + cyclophosphamide and palliative radiotherapy for bone metastases. The patient died 26 months after surgical treatment. The cases have been assessed and compared with cases in the literature.

CONCLUSION

No specific diagnostic criteria or treatment strategies have been developed for LGMS. The treatment used for LGMS is the same as that used for sinonasal cancer radical tumor excision; adjuvant radiotherapy or chemoradiotherapy should also be considered. They have low malignant potential but are highly invasive, tend to recur, and metastasize to distant sites. Patients should undergo regular follow-up examinations to detect recurrence or metastasis at an early stage. Patients should be treated and observed at the highest referral centers.
A Study On The Factors Influencing Purchase Behaviour Of The Customers Towards Silk Sarees In Kancheepuram
Authors: Sivakavitha S. , Selvasundaram Dr. K.
Published: April 2024

Studying the behavior of female consumers has become crucial. Consumers reign as the pivotal force in markets. Kanchipuram Silk boasts a rich historical legacy dating back to the early era of South India under the Pallavas. As a temple city and former capital of various South Indian dynasties, the silk handloom industry has thrived here, supported by royal patronage, elevating weavers to a prominent position in the social hierarchy. Businesses cannot operate without consumers. The rising costs of raw materials, particularly zari, emerge as a significant production hurdle, accompanied by challenges like working capital issues, increased use of counterfeit zari, and low wages. In marketing, the primary concern is the escalating prices of finished goods due to input cost hikes, followed by the influx of silk fabrics containing fake zari, unfair trade practices such as selling non-Kanchipuram products under its brand name, intermediary misconduct, lack of advertising, and the availability of cheaper alternatives. Understanding consumer behavior delves into their purchasing patterns, considering their roles as users, payers, and buyers. People's desires for products and services have dramatically expanded, leading to shifting attitudes and behaviors that can be sensitive to price fluctuations. To establish a study framework, various paradigms of thought that have influenced the discipline of consumer behavior need to be considered.
Impact of the Corona Pandemic on Healthcare Professionals
Authors: Alotaibi Nawaf Masri Noor , al-Harbi Nawaf Saleh , Al-Moqati Mohammed Faihan , Al Shehri Fawaz Nasser Fawaz , Alsulami Ibrahim Dakhel , Alzahrani Zahra Gumaan , Ayaz Ghassan Abdulwahab , Allaf Sultan Tawfik , Alharbi Naif Saleh
Published: April 2024

The advent of the Corona pandemic has brought about significant changes in various sectors, with healthcare professionals bearing the brunt of the crisis. This essay examines the impact of the pandemic on healthcare professionals at the Master level. The study explores the challenges faced by healthcare professionals, including increased workloads, mental health struggles, and the risk of exposure to the virus. Additionally, the essay considers the measures taken by healthcare institutions to support their staff during these challenging times. The findings suggest that the pandemic has fundamentally altered the landscape of healthcare delivery and underscore the importance of prioritizing the well-being of healthcare professionals to ensure the sustainability of the healthcare system.
PERFORMANCE OF SHARI’A BANKING IN INDONESIA BEFORE AND DURING THE COVID 19 PANDEMIC: ISLAMICITY PERFORMANCE INDEX APPROACH
Authors: Masyitah As Sahara  , Charly Marlinda  , Sri Kurnia  , Rachmad Chartady
Published: April 2024

This research aims to determine the performance of Islamic banks using the Islamicity Performance Index approach before and during the Covid-19 pandemic. The method used in this research is a quantitative descriptive method. The object of this research is all sharia commercial banks in Indonesia. The data for this research comes from the financial reports of Islamic commercial banks for the period 2018 - 2021. The research results show that in the profit sharing ratio before and during the pandemic, only Bank Muamalat Indonesia received a fairly good title with a percentage below 30%. The results of the zakat performance ratio show that all banks still have a bad reputation in pandemic conditions and during the pandemic. For equitable distribution ratio, only Bank Jabar Banten Syariah received a fairly good title from qard and donations, and from the labor load of Bank Muamalat, Aceh Syariah and Bukopin Syariah which was able to survive with IPI standards, while in terms of net profit only Bank Mega Syariah was able to survived the pandemic with a percentage of more than 35%. For Islamic investment vs non-Islamic investment, the entire sample of Islamic commercial banks received a very good rating. And for Islamic income vs non-Islamic income, all banks in the sample received a very good title
AN ANALYSIS OF JARGONS USED BY RECEPTIONISTS IN FRONT OFFICE HOTELS AT LOMBOK
Authors: Siti Lathifah
Published: April 2024

This study aimed at identifying and describing the linguistic forms, the meanings and the functions of jargon used by receptionists of the front office department at Lombok Hotel. This study was conducted in qualitative method. The front office jargons were investigated in spoken and written forms. The subjects of this study were receptionists of the front office department at Lombok. The methods of data collection were observation, documentation and interview. This study found  jargon were used by receptionists in front office department. It was found that the jargon was in the form of noun phrases abbreviation, noun, clipping, affixation, borowing , acronym , preposition phrases , verb , adjective , and coinage . The meanings of jargon were identified by investigating technical meaning. Besides, this study found that there were two functions of the jargon, (1) providing a technical or specialist language to make communication more efficient and (2) encouraging group solidarity. This study concluded that jargon is a way toexpress the feeling of the community and also have their own specific language
OPTIMIZATION OF RETENTION POND IN FLOOD CONTROL EFFORTS IN PEKANBARU (URBAN FLOOD SYSTEM IMPROVEMENT PROJECT)
Authors: Erni Yulianti  , Eko Prasetyo
Published: April 2024

This research aims to optimize the function of retention ponds as part of the urban flood control improvement project in Pekanbaru. Evaluation was conducted on the capacity and efficiency of retention ponds, with a focus on spatial distribution, sustainability, and environmental impact. The findings of this study provide a foundation for formulating concrete and data-driven improvement recommendations. The spatial distribution of retention ponds is crucial in understanding their effectiveness in mitigating flood risks. Evaluation of the actual capacity of retention ponds provides an overview of their ability to accommodate excess rainwater, while efficiency identifies factors for enhancement and improvement. Improvement recommendations include increasing capacity, implementing advanced technology, and developing data-driven solutions. Involving stakeholders, including local government, research institutions, and the community, is a strategic step to ensure successful implementation. The application of sensors and geographic information systems (GIS) can enhance the effectiveness of retention pond operational management. Sustainability of solutions is realized through routine maintenance, performance monitoring, and multi-stakeholder collaboration. This research significantly contributes to urban flood management in Pekanbaru by providing concrete, data-driven recommendations for the retention pond system.
HUMAN RELATIONS AND THE USE OF NEW MEDIA TECHNOLOGY IN ORGANIZATIONAL COMMUNICATION AT PT. LANTERA SEJAHTERA INDONESIA
Authors: Barra P. Pradja  , Mirza Ronda  , Jamalullail
Published: April 2024

This research was conducted to see the influence of Human Relations and the Use of New Media Technology in Organizational communication at PT. Lantera Sejahtera Indonesia. The research method used a census method with a population of 65 people. Data collection techniques using questionnaires and questionnaires consisting of 82 questions divided into 3 parts, namely human relations, the use of new media and organizational communication. Data analysis in this study used the SEM method. Hypothesis testing shows that human relations have a significant effect on organizational communication. This indicates that good human relations will contribute well to organizational communication. The use of new media in organizations has a significant effect on organizational communication. Furthermore, from the results of the hypothesis test, it can be seen that human relations and the use of new media together can affect organizational communication at PT Lantera Sejahtera Indonesia. From the results of this study, researchers provide several suggestions to improve organizational communication at PT Lantera Sejahtera Indonesia to be able to improve human relations for the better so that organizational communication becomes better. Furthermore, the use of new media can increase the effectiveness of communication built at PT. Lantera Sejahtera Indonesia
THE IMPACT OF COMPANY CHARACTERISTICS TO INCREASE COMPANY VALUE WITH CORPORATE RISK MANAGEMENT AS MEDIATION IN COMPANIES LISTED ON THE IDX IN 2016-2020
Authors: Sarsiti  , Juni Trisnowati  , Erni Widiastuti
Published: April 2024

The research objectives are based on the research of Bohnert, A., et al., 2023 and Nguyen, Lan, et al. 2021, namely to examine the impact of size and leverage on firm value with enterprise risk management (ERM) as mediation. The sample technique used is purposive sampling, and the data used is secondary data from annual financial report data listed on the Indonesia Stock Exchange from 2016-2020, totaling 15 property and real estate industry sectors. Path analysis and the Sobel test are used in the data analysis technique. The findings indicated that: (1) firm size has a negative and insignificant impact on ERM; (2) leverage has a positive and insignificant impact on ERM; (3) firm value is positively but insignificantly impacted by company size and leverage; and (4) ERM has a negative and insignificant impact on firm value. (5) The impact of firm size and leverage on firm value is not mediated by ERM
POLITICAL CONFLICT AND COMPROMISE IN THE JOB CREATION BILL DISCUSSION
Authors: M. Masad Masrur
Published: April 2024

Regulatory reform by amending various provisions in dozens of laws into a single Omnibus Law on Job Creation has been rejected because it is considered to eliminate protection for workers/labourers, and expand the dominance of employers. The wave of rejection continues to strengthen, raising questions about the process of political communication, conflict and negotiation, and political compromise between political forces in the DPR (Parliamentary Institutions). With a constructiveist paradigm and case study method, and supported by several theories from political science, political communication, negotiation theory, conflict theory, as well as several concepts regarding political compromise, the results showed that political communication in the discussion of the Job Creation Bill took place systematically by placing the authority of political parties as decision makers. Political conflict occurs due to inflexible negotiations. Political negotiations carried out through a principle-based negotiations approach, although it can accelerate the discussion process, is unable to guarantee the effectiveness of political compromise. The Job Creation Bill comes as an orthodox legal product and was declared unconstitutional by the Constitutional Court. Four things that become the findings of this research are (1) the dynamics of political communication are strongly influenced by the presidential-multiparty political system that produces majoritarian power, so that it has consequences for political alignments; (2) political conflicts that arise due to polarisation of political support have presented inflexible political communication, (3) principle-based political negotiations are pragmatically able to accelerate discussions but do not guarantee resistance/rejection by the public; and (4) political compromise through the stages of strategy development, relationship management, and decision making, cannot be a form of agreement that can accommodate all parties
Frequency and risk factors of cigarette smoking among male medical students of Bacha Khan Medical College, Mardan
Authors: Hanfi Hanifullah , Ahmad Abdul Qadeer , Ahmad Waqas , Masroof Usama , Khan Dawood , Khan Shahkar Ali , Rehman Abdur , Suleman Muhammad
Published: April 2024

Tobacco consumption is a major global health issue that contributes significantly to morbidity and mortality rates. The World Health Organization (WHO) estimates that over five million deaths occur each year due to tobacco use, projected to rise to 8 million by 2030. Furthermore, current research reveals that 47% of males and 12% of females worldwide smoke. Of particular concern is cigarette and tobacco use among medical students, given their role in crafting public health policy and guiding society's tobacco prevention measures. Studies show that smoking rates among medical students in developing countries are between 16-21%, with multi-country surveys in countries like Malaysia, India, Pakistan, Nepal and Bangladesh indicating rates between 6.7% and 17.8%. For example, a study conducted on medical students in Damascus University Faculty of Medicine revealed a 10.9% prevalence of cigarette smoking, 23.5% for water pipe, and 7.3% for both, with higher rates reported among final-year students. Likewise, a study of Rawalpindi Medical College students found that 24% had smoked at least once, with greater prevalence among hostellites rather than day scholar students.
Estado nutricional, nivel socioeconómico y riesgo de enfermedad crónica no trasmisible en adultos
Authors: Nariño Ilva , Bruce Gauciry , Paredes Yorman , Figueroa Johana , Peña Rosalyn
Published: April 2024

Objetivo: relacionar el estado nutricional y el nivel socioeconómico con el riesgo de presentar una enfermedad crónica no transmisible (ECNT) los adultos de la comunidad de Belén de Mérida-Venezuela. Metodología: investigación de campo, corte transversal, correlacional y con un diseño analítico. De la población representada por 300 personas, a través del muestreo probabilístico aleatorio simple, se obtuvo una muestra de 45 individuos mayores de 20 años. Se utilizaron varios instrumentos: la Encuesta socioeconómica y nutricional aplicada por Barriga; el Índice de masa corporal (IMC) y el diámetro cintura/género de la Organización Mundial de la Salud (OMS) y el método de estratificación social Graffar. Se aplicó estadística descriptiva e inferencial. Resultados: predominó el género femenino (53,2%), el rango de edad estuvo entre 25 y 44 años con un 24,4% para las mujeres. El IMC por género reportó un mínimo de 18 kg/m2 y un máximo de 32 kg/m2, donde el 50% de los datos centrales en el género femenino y masculino están en un 23,1 kg/m2 y 23,7 kg/m2 con un estado nutricional normal. El 55,56% se ubicó en el estrato socioeconómico IV. El 71,11% presentó un riesgo bajo de padecer alguna ECNT. Conclusiones: no hubo asociación entre el estado nutricional ni el nivel socioeconómico con el riesgo de presentar ECNT.
Formación docente: experiencias y percepciones de un grupo de profesores universitarios
Authors: Rodríguez Ana , Sánchez Eduardo
Published: April 2024

Introducción: la formación a nivel pedagógico representa un elemento fundamental del proceso educativo. Objetivo: indagar acerca de la formación docente desde las experiencias y percepciones de un grupo de profesores universitarios. Metodología: estudio cuantitativo de diseño no experimental, con un nivel descriptivo. La población fue muestral y estuvo constituida por 8 profesores del Departamento de Estadísticas de Salud del Núcleo Universitario "Dr. Rafael Gallegos Ortiz" de la Universidad de Los Andes. El instrumento aplicado fue una entrevista semiestructurada. Resultados: el 62,5% de los participantes eran de sexo femenino y entre 30 y 40 años de edad. El 87,5% manifestó poseer una carga horaria entre 20 a 40 horas semana; 62,5% refirió que su dedicación era tiempo completo y el 100% indicó no poseer experiencia docente al momento de ingresar a la universidad ni tampoco formación docente (62,5%). Con relación a las experiencias y percepciones sobre la formación, estas permitieron inferir que la concreción de la educación como parte de la vida, así como, el desempeño en el ejercicio y la capacitación docente, los ha conllevado a actualizar y mejorar sus capacidades didácticas y métodos de enseñanza después de ingresar a la universidad. Conclusión: la mayoría de los participantes del estudio, no poseían formación docente al momento de ingresar a la universidad, pero la praxis y el interés contribuyó a aumentar sus competencias.
Caso clínico quirúrgico: Laparotomía exploratoria
Authors: Carrillo Nathalie , Vega María
Published: April 2024

La Laparotomía exploratoria es la apertura del abdomen que permite evaluar los órganos y tejidos contenidos en el mismo, con la intención de diagnosticar una patología que no ha sido posible identificar a través de otros medios de estudio, por lo que, el personal de Enfermería debe desarrollar destrezas en el momento de desenvolverse en el área quirúrgica, tomando en cuenta que su función no solo va direccionada a la instrumentación de la cirugía, sino al proceso perioperatorio que se encuentra atravesando el paciente, con el fin de brindar cuidados oportunos para evitar las posibles complicaciones que se pueden presentar y que disminuyan el tiempo quirúrgico, fomentando así la recuperación eficaz. Conocer la técnica quirúrgica que se va a llevar a cabo facilita la etapa intraoperatoria, fundamental en la revisión del presente caso, cuyo objetivo fue aplicar el procedimiento quirúrgico de la Laparotomía exploratoria permitiendo así orientar acciones adecuadas al momento de ser parte del equipo encargado, y que durante el aprendizaje alcanzado en el Diplomado Básico en Instrumentación Quirúrgica que dicta la Universidad de Los Andes, se pudo construir con pensamiento crítico y conciencia quirúrgica.
Caso clínico quirúrgico: Tumor de colon sigmoide con tratamiento quirúrgico de colostomía en asa del sigmoide
Authors: Peña Mariana , Vega María
Published: April 2024

El objetivo del presente artículo es describir y explicar la técnica quirúrgica en Enfermería del caso clínico de un paciente masculino, con diagnóstico médico de tumor de colon sigmoide, a quien se le realizó tratamiento quirúrgico de colostomía en asa del sigmoides, realizado en el Instituto Autónomo Hospital Universitario de Los Andes (IAHULA) de Mérida-Venezuela, como requisito del Diplomado Básico en Instrumentación Quirúrgica.
Entre el "país vegetal" y el "país mineral". La identidad de los Estados Unidos de Venezuela en las exposiciones internacionales de 1901 a 1930
Authors: Cherini Serenella
Published: April 2024

A través del lente de una historia social del diseño y la cultura material, el siguiente artículo expone cómo Venezuela, al participar en siete exposiciones internacionales de 1901 a 1930, buscó representarse como una nación articulada desde el siglo anterior con el capitalismo, pretendiendo lucir organizada. y consciente del valor de su pasado y de sus recursos presentes, dispuesta a modernizarse al transitar entre su vieja fórmula de «brazos y capitales» como país exportador de alimentos y productos primarios y el inicio de su nuevo «capitalismo rentístico» como país exportador de petróleo
Reseña: Telegrama Federal de la Dirección General de Correos en Caracas a la Inspectoría Técnica Postal de Tovar (Mérida), 1938
Authors: Rojas Amarilis
Published: April 2024

El presente documento es una muestra de la importancia de la información escrita en Venezuela en la primera mitad del siglo XX. Además, ayuda a entender la evolución de los medios de comunicación en el contexto venezolano en momentos definitorios para el país. El mismo es un telegrama que cuenta con el membrete institucional característico de la época y hace referencia a la organización federal del momento. Igualmente, permite observar cómo se establecía un número de palabras escritas para la redacción del contenido del mismo.
Imaginación e imaginarios geográficos en los trópicos. Naturaleza y cultura en la visión del paisaje en los jesuitas del siglo XVIII
Authors: Cuevas Luis
Published: April 2024

La experiencia tropical que comunican los textos de los jesuitas en los espacios misioneros se resuelve en el campo de lo que es posible normar, describir y expresar mediante diversos lenguajes. La emoción ante los paisajes tropicales también se contiene en texto esos, y se coloca a camino entre la retórica y la percepción del primer encuentro en los espacios interiores. Estas experiencias del viaje al interior del Continente instituyen un imaginario geográfico de América, donde la naturaleza y el paisaje comportan un lugar central en la espacialización de los saberes durante la segunda expansión de la racionalidad occidental en el siglo XVIII. En tal sentido, esta investigación se propone examinar en algunos textos, los discursos y la coexistencia de acercamiento estético y pragmático que suponen formas de valoración del paisaje americano, cuyos registros, permiten comprender la construcción de las imágenes y las diversas formas de valoración paratáctica y liminar de los paisajes interiores indianos
María Teresa Boulton y Olga Santeliz Cordero (Compiladoras). Arístides Rojas, un Multifacético artesano de la Historia. Abediciones, Fundación John Boulton, Vollmer Foundation INC, H.L. Boulton & Cia, S.A., 2023, 111pp
Authors: Hernández María
Published: April 2024

El libro que reseñamos en estas líneas es una iniciativa de la Fundación John Boulton con el patrocinio de otras instituciones y que tiene como tema central el estudio de Arístides Rojas, un personaje del siglo XIX venezolano, que a luz del siglo XXI es considerado un Multifacético artesano de la Historia, como reza en el título de esta publicación.
Contaminación por macrobasura marina en la barra de Hong Sound, Bluefields, Costa Caribe Sur de Nicaragua
Authors: Ebanks Mongalo Billy Francis , Moody Garth Shanely Nadisha , Rivas Suazo Enoc Geremías , Siu Estrada Eduardo Alexander , Flores-Pacheco Juan Asdrúbal
Published: April 2024

La contaminación por basura marina es un problema creciente, vinculado al aumento poblacional y al consumo de productos envasados y deficiente gestión de residuos, amenazando la biodiversidad y los servicios ambientales en ecosistemas costeros. El objetivo de este estudio fue evaluar el estado de contaminación por macrobasura en la playa de la barra de Hong Sound de la laguna Bluefields, Costa Caribe Sur de Nicaragua. La investigación es descriptiva de corte transversal con enfoque cuantitativo, desarrollándose muestreo por conveniencia. El 21 de julio del año 2022, se realizó un muestreo en 1025 m2 de playa, la basura marina fue clasificada según las características físicas en: plásticos (botellas plásticas, bolsas plásticas, poroplast y plásticos duros), caucho, vidrios, tela, madera procesada y metal, posteriormente serían pesados utilizando una balanza de reloj con unidad de medida en kilogramos. Se registró un total de 18.058 kg de basura marina, con densidad de 0.0176 kg/m2, en su mayoría plástico, con peso de 13.191 kg, ocupando el 73.1% de toda la basura. Los tipos de basuras encontrados fueron plásticos, vidrio y caucho, los cuales son arrastrados por acción del viento, corrientes o por personas que visitan la playa, esta dispersión es causada por mal manejo de residuos sólidos en asentamientos humanos. En la zona de estudio, la mayor contaminación es por plásticos, siendo necesario desarrollar estrategias para reducción de contaminación de playas por basura marina y de esa manera disminuir los riesgos ambientales a la biodiversidad existente en la zona de estudio.
Gestión del conocimiento estudiantil en los paradigmas psico pedagógicos contemporáneos
Authors: Giusto-Largaespada Mauro A.
Published: April 2024

El objetivo de la investigación documental fue analizar los avances de la gestión del conocimiento aplicada a la producción intelectual estudiantil a nivel de grado universitario, desde los distintos paradigmas psicoeducativos contemporáneos. Esta caracterizó y contrapuso la concepción de conocimiento y aprendizaje, producción y gestión del conocimiento y las estrategias de divulgación de los resultados, aplicados a la producción intelectual estudiantil a nivel de grado. Los paradigmas educativos analizados fueron: tradicional, conductista, constructivista, sociocrítico y humanista. Se concluyó que, para adecuar la educación superior a la sociedad del conocimiento, es obligatorio adecuar las prácticas pedagógicas y la gestión universitaria. La gestión del conocimiento estudiantil es un instrumento útil para el incremento de la calidad en la educación superior, ya que significa un recurso para el desarrollo científico, económico, social y cultural. No obstante, para su institucionalización se requiere la renovación paradigmática de los miembros de la academia a nivel institucional, local y global.
Cotton (Gossypium hirsutum) Response to Plant Protection Products using Different Spray Nozzles
Authors: Jordan David
Published: April 2024

Application of dicamba to dicamba-tolerant cotton (Gossypium hirsutism L.) cultivars (Xtend Cotton, Bayer Crop Science, Research Triangle Park, NC) requires use of nozzles that deliver large spray droplets to avoid off-site movement through particle drift onto susceptible crops and other plants including endangered species. Twenty trials over a three-year period were conducted to determine if nozzles required to deliver dicamba plus glyphosate would be equally effective in delivering other pesticides including the herbicide glufosinate, the plant growth regulator mepiquat chloride, the insecticide bifenthrin plus dichrotophos and co-application of ethephon plus thidiazuron plus tribufos for removal of cotton foliage to improve harvest efficiency. Agrichemicals were applied using: a) Air Induction (AI) nozzles for agrichemicals except dicamba plus glyphosate b) Turbo Teejet Induction (TTI) nozzles for all agrichemicals c) TTI nozzles for glufosinate and dicamba plus glyphosate and AI nozzles for other agrichemicals. Applications were made in 145 L/ha at 152 kPa at a ground speed of 5 km/h. Cotton height at the end of the season, node above first fruiting branch, nodes above cracked boll, node of uppermost boll, total nodes, lint yield, and cotton fiber quality were similar regardless of nozzles used to deliver agrichemcials. Control of a complex of broadleaf signal grass (Urochloa platyphylla L.), goosegrass [Eleusine indica (L.) Gaert.], and large crabgrass (Digitaria sanguinalis L.) and Palmer amaranth (Amaranthus palmeri Watts.) was slightly lower when glufosinate was applied with TTI nozzles rather than AI nozzles. However, control of these weeds was similar regardless of nozzle selection when dicamba plus glyphosate was applied after glufosinate. These results suggest that growers can use nozzles that limit off-site movement through particle drift of agrichemicals throughout the cropping cycle with no major adverse effect on weed control and cotton growth and yield.
The Social Economic Contributions of NIPSCO (Northern Indiana Public Service Company) to Northwestern Indiana: A Brief Economic Report Analysis
Authors: Lin Tin-Chun
Published: April 2024

This brief economic report analysis highlights that NIPSCO is an important economic driver in Northwestern Indiana due to their high investments, including purchases of goods and services, and employing a highly skilled labor force. NIPSCO’s significant capital investments develops a modern and reliable energy generation and distribution infrastructure, and hence in turn supports the region’s economic development. In addition, both GDP and employment multipliers for NIPSCO demonstrate that due to the energy industry in Northwestern Indiana, NIPSCO creates more additional GDP and jobs in other industries in the region. In short, this brief economic report analysis shows that NIPSCO makes significant social economic contributions to the region’s economy in Northwestern Indiana.
Estado do conhecimento: investigação e reflexão a respeito da implementação de tecnologias digitais educacionais nos processos formativos das escolas públicas brasileiras
Authors: Bandiera Eliara Maria , Busatta Camila Aguilar
Published: April 2024

Abordar questões como a eficácia pedagógica das ferramentas digitais, a equidade no acesso às tecnologias e a necessidade de desenvolver habilidades digitais entre os alunos, é de extrema importância, por esse motivo este estudo visa fornecer insights valiosos para informar práticas educacionais eficazes e promover a aprendizagem efetiva dos estudantes na era digital. O “Estado do Conhecimento”, de caráter bibliográfico, apresenta a intencionalidade em realizar uma investigação, análise e reflexão acerca da inserção de tecnologias digitais no contexto escolar e de que forma essas mídias podem auxiliar no processo de ensino e aprendizagem, contribuindo de forma mais efetiva para o desenvolvimento de habilidades e competências por parte dos estudantes. A pesquisa discorre sobre a importância da formação inicial e a formação continuada dos professores da educação básica, para que possam desenvolver seus planejamentos de aula de forma atrativa e engajadora, utilizando métodos distintos e novas maneiras de ensinar, considerando a infraestrutura e a realidade das escolas públicas brasileiras. A investigação ocorreu no período entre outubro de 2022 a janeiro de 2023, utilizando como fonte de pesquisa o Portal de Teses e Dissertações da CAPES, a partir de descritores específicos correlacionados com a temática pesquisada, considerando os últimos 10 anos de trabalhos publicados na área de tecnologias, aprendizagem e formação de professores. No decurso das investigações e análises, percebe-se que ainda há insuficiência nas formações docentes, principalmente para com a inclusão das tecnologias digitais em sala de aula. Outro ponto de reflexão que merece atenção, são as melhorias basilares e imprescindíveis nas condições estruturais das escolas públicas brasileiras, tendo em conta, inúmeros problemas e desafios na infraestrutura, para a inserção de novas tecnologias nos ambientes educacionais.
A Twist in the Plot - Systems Thinking and Building Models for Analyzing Literary Artwork
Authors: Ben Moshe Zarfati Sheli
Published: April 2024

Models are being used extensively for practicing and understanding scientific, engineering and mathematical subjects, but are rarely used as art analyzing tools, particularly, in learning environments. Contrarily, using art to explain mathematical ideas is not unprecedented. Strogatz (1988), for example, built a model based on Romeo and Juliet’s love story and used it to explain the idea of differential mathematics, and system dynamics. Artwork, specially written and plastic classics, is a fixed form of art. We frame them and put them in a gallery, or a book (digital or physical). We don’t try to “fix” them or optimize their functioning, we analyze them to find meaning, intention, and patterns. In this article, we aim to show how, by building models combined with simple mathematical representations and analogies, it is possible to understand literary texts, from the prism of system and complexity theories, which emphasize the dynamic, non-linear, and non-reductionist aspects of the observed. We’ll demonstrate how modeling processes of three cultural assets, allow active correspondence with the original textual art, by treating them as systemic objects with interactions and dynamics. They will be analyzed while raising questions about the significance of modeling as a cognitive learning process.
Systems Thinking in Cybersecurity; Ending with the Beginning in Mind.
Authors: Collins Michael
Published: April 2024

Despite the increasing complexity of the digital landscape and the rise in cyber-attacks,systems thinking has not been widely utilized in cybersecurity. This research paper employs a SystemsLiterature Review to examine the current state of knowledge regarding the use of systems thinking incybersecurity and identifies several issues, including the lack of consistency in defining "systemsthinking”, narrow use cases, and a lack of empirical evidence supporting the reviewed methods. Differentresearchers and practitioners may have varying interpretations of this concept, leading to confusion and alack of standardizedapproaches. This inconsistency hampers the development of a cohesive frameworkfor applying systems thinking in cybersecurity. To address these challenges, future research should focuson developing a common understanding and definition of systems thinking in the context of cybersecurity.This will facilitate communication and collaboration among researchers and practitioners, leading to moreconsistent and effective approaches. Additionally, there is a need for empirical studies that rigorouslyevaluate the impact of applying systems thinking in cybersecurity. These studies should assess theeffectiveness of different methodologies and frameworks in real-world scenarios, providingevidence-based insights into their benefits and limitations. In conclusion, while the application of systemsthinking in cybersecurity holds promise, there are challenges that need to be addressed. Resolving thesechallenges is crucial for advancing the field and establishing a solid foundation for the application ofsystems thinking in cybersecurity.
Temporal evolution of nitrate in Meoqui-Delicias aquifer in Chihuahua, Mexico
Authors: Espino Valdés María Socorro , Villalobos Gutiérrez Miriam Nayeli , Gutiérrez Mélida , Silva Hidalgo Humberto , Pinales Munguía Adán
Published: April 2024

The continued input of nitrate (NO3) into groundwater is a global problem, mainly associated to excess fertilizer and improper disposal of human and livestock waste. Nitrate accumulation in oxic aquifers of semiarid areas makes these zones especially susceptible to pollution. Nitrate in Meoqui-Delicias aquifer, located in an important irrigation district in Chihuahua, Mexico, was quantified in 2021 in 63 drinking water wells.  Samples collected were analyzed in laboratory and results were compared to 2003 and 2006 data available for those wells. Nitrate values varied from 0.7 to 23.2 mg/L and 22 % of the wells contained NO3 above drinking water guidelines (10 mg NO3-N/L). A low to moderate nitrate pollution index (NPI) and a slight NO3-N variation with time was observed for most wells. Values of NO3-N/Cl < 1.0 support an anthropogenic origin of nitrate. No association was found between NO3-N and well depth. The most susceptible areas to nitrate contamination were identified as those areas with high NO3-N and increasing concentration with time. The lack of a pattern of contamination suggested leakage of manure leachate at a few points as the most likely contamination source. The consistently high NO3-N content (>10 mg/L) in three deep wells constitutes a serious concern. 

DOI: https://doi.org/10.54167/tch.v18i1.1415
Uusien teosten julkaisusta keskiajalla
Authors: Niskanen Samu
Published: April 2024

Ainakin niin kauan kuin ihmiskunta on kyennyt tarinoimaan kirjoittamalla, sillä on ollut tarve kartoittaa muinaisuutta. Tällainen harrastuneisuus on kantanut nykypäiviin saakka. Olenhan itsekin uhrannut parhaat vuoteni sen palveluksessa. Menneisyyttä tutkies- samme haemme vastauksia kysymyksiin, jotka askarruttavat omassa ajassamme. Siksi historian aarreaitta ei ole päässyt tyhjentymään eikä niin voi koskaan tapahtuakaan. Koska menneisyydestä löytyy vastaus syvälliseen identiteettikysymykseen mistä tulemme, historia säilyy alati ajankohtaisena.
Kosmopoliitti kylpyläkaupungissa
Authors: Kekäläinen Markku
Published: April 2024

Ivan Turgenev kuvaa romaanissa Savua, (1867, suom. Matti Lehmonen, 1981) illan huvitusten alkamista Baden-Badenissa. Ohjelmiston kansainvälisyys heijasti kosmopoliittista kuulijakuntaa. Lounaissaksalaiseen kylpyläkaupunkiin tungeksi 1800-luvun puolivälissä aristokraatteja – sekä aitoja että omatekoisia – taiteilijoita, älykköjä, vallankumouksellisia, tyhjäntoimittajia, uhkapelureita, puolimaailman naisia Euroopan kaikilta kulmilta, myös Venäjältä. Puoliksi ranskalaistuneet pietarilaiset ja moskovalaiset saattoivat kaupungin vapaamielisessä ilmapirissä purkaa kotimaansa poliittisia turhautumia.
Paluu maatalouden vallankumouksen juurille
Authors: Laine Kirsi
Published: April 2024

Arvio teoksesta: Mats Morell: Agrar revolution. Jordbruksproduktionen i Uppsala och Västmanlands län 1750–1920. Uppsala Studies in Economic History 121, Uppsala universitet 2022. 467 s. ISBN 978-91-513-1451-8. Sähköinen julkaisu: urn:nbn:se:uu:diva-470482
Akateemikko, professori Päiviö Tommila (1931–2022)
Authors: Lähteenmäki Maria
Published: April 2024

Juhani Päiviö Tommila syntyi Eero ja Salli Tommilan esikoisena 4.8.1931.