bluuebunny/crossref_metadata_2025 huggingface dataset:
Anti-proliferative activity of yerba mate (Ilex paraguariensis) aqueous extracts on human colorectal cancer cell lines
Authors: Jason Saleh Ali , Othman Leen , Elchoueiry Michel , Ghanem Rita , Bazzi Samer , El-Sabban Marwan , Abdel-Massih Roula M
Published: October 2021

Background: Yerba mate, a popular, tea-like beverage prepared from the dried leaves of Ilex paraguariensis, is widely consumed, and has several reported health benefits. Compared with other herbal teas, the effect of yerba mate on human cells in the context of cancer has not been extensively studied. The method of extraction of bioactive compounds from the yerba mate leaves plays an important role in its effect on cancer cells. Methods: In this study we assessed the viability, anti-proliferative, and apoptotic effect of the aqueous yerba mate extract, prepared using the same conditions employed for consumption, on different human colorectal cancer cell lines (Caco-2, HT-29, and HCT116) and on the non-tumorigenic human colon epithelial cell line (NCM460).Results: Cytotoxicity of aqueous yerba mate extract was studied and a dose-dependent decrease in viability was observed in all the tested cell lines. At 24 hrs., viability decreased to 19.7% with Caco-2 cells, 2.7% with HCT116, and 8.4% with HT-29 cells at a concentration of 4.8 mg/mL of yerba mate extract. The effect was less prominent on the NCM460 cell line where the viability of cells at the same concentration was 65.2%. Yerba mate extract also showed concentration-dependent anti-proliferative effects as determined by the WST-1 proliferation kit. IC50 values ranged between 0.22-0.69 mg/mL at 24 hr for cell lines tested. To study whether cell death was due to apoptosis, Caco-2 cells were stained with Annexin V-FITC assay and an increase in the percentage of late apoptotic Caco-2 cells was observed with yerba mate extract at 0.6-4.8 mg/mL. Cell cycle analysis using DNA content by flow cytometry showed an increase in the percentage of Caco-2 cells in the subG0/G1 phase and the G0/G1 phase after treatment with 2.4 mg/mL extract. Collectively, our data suggest that yerba mate aqueous extract exhibits an anti-proliferative effect on tested cell lines by inducing apoptosis.  Conclusions: Yerba mate aqueous extract exhibits a strong anti-proliferative activity against adenocarcinoma cell lines studied and constitutes a promising functional food adjuvant to anti-cancer therapy. Further work is needed to identify active components and mechanisms of action. Keywords: Aqueous extract, yerba mate, anti-proliferative activity, adenocarcinoma cell lines
Factors affecting reorientation of hydraulically induced fracture during fracturing with oriented perforations in shale gas reservoirs
Authors: Li Qingchao , Zhou Liang , Li Zhi-Min , Liu Zhen-Hua , Fang Yong , Zhao Lei , Han Ying
Published: October 2021

Hydraulic fracturing with oriented perforations is an effective technology for reservoir stimulation for gas development in shale reservoirs. However, fracture reorientation during fracturing operation can affect the fracture conductivity and hinder the effective production of shale gas. In the present work, a numerical simulation model for investigating fracture reorientation during fracturing with oriented perforations was established, and it was verified to be suitable for all investigations in this paper. Based on this, factors (such as injection rate and fluid viscosity) affecting both of initiation and reorientation of the hydraulically induced fractures were investigated. The investigation results show that the fluid viscosity has little effect on initiation pressure of hydraulically induced fracture during fracturing operation, and the initiation pressure is mainly affected by perforation azimuth, injection rate and the stress difference. Moreover, the investigation results also show that perforation azimuth and difference between two horizontal principle stresses are the two most important factors affecting fracture reorientation. Based on the investigation results, the optimization of fracturing design can be achieved by adjusting some controllable factors. However, the regret is that the research object herein is a single fracture, and the interaction between fractures during fracturing operation needs to be further explored.
Effect of Gaseous carburizing thermochemical treatment on tribological behavior of Ti–6Al–4V alloy
Authors: Kamel Fedaoui , Talhi Amar , Touhami Mohamed Zine
Published: October 2021

This study, concerns the improvement of the hardness and resistance to wear of the Ti-6Al-4V alloy surface by means of thermochemical treatment, for obtaining coatings on the Ti-6Al-4V alloy gives performance of resistance to wear phenomena. Three-thermochemical treatment time (2h, 4h, and 6h) was chosen for investigation of the effect of such treatment on this alloy. The hardness test under an indentation load of 50 gf with a Vickers pyramidal indenter revealed that the surface hardness is 335 Hv for the untreated samples. On the other hand the hardness reaches approximately 1500 Hv during gas cementation at 930 °C for variable times (2h, 4h, 6h) followed by quenching at 840 °C in an oil medium, which was accompanied by a significant improvement in wear resistance. The characterization of the modified surface layers was made by means of a microscopic analysis and by X-ray diffraction. The case-hardening made it possible to obtain a wear resistance greater than that of the alloy not treated, minimal loss of mass by dry friction and an improvement in roughness as well as a good coefficient of friction.
The effect of using polypropylene fibers on the durability and fire resistance of concrete
Authors: Suiffi Hassan , El Maliki Anas , Majid Fatima , Cherkaoui Omar
Published: October 2021

In order to study the effect of polypropylene fibers on the durability of cementitious composites, several experimental tests have been carried out in the laboratory. The composite was tested with different volume fractions of polypropylene fibers (0.05%, 0.10%, 0.30% and 0.50%). All the results relating to the indicators (porosity accessible to water εb, to the oxygen permeability Kapp.gas and diffusivity Dns) indicate that the addition of polypropylene fibers in a cement matrix represents only a small effect on durability. This panel of general sustainability indicators can be supplemented by indicators more specific to each degradation process identified or envisaged depending on the environmental conditions of the structure. However, the addition of the volume fraction of polypropylene fibers (0.50%) in a cementitious composite, increases fire resistance. Such behavior gives fiber composites interesting properties which favor their use in structures exposed to fire risks.
Mining Clinical Process from Hospital Information System: A Granular Computing Approach
Authors: Tsumoto Shusaku , Hirano Shoji , Kimura Tomohiro , Iwata Haruko
Published: October 2021

Data mining methods in medicine is a very important tool for developing automated decision support systems. However, since information granularity of disease codes used in hospital information system is coarser than that of real clinical definitions of diseases and their treatment, automated data curation is needed to extract knowledge useful for clinical decision making. This paper proposes automated construction of clinical process plan from nursing order histories and discharge summaries stored in hospital information system with curation of disease codes as follows. First, the system applies EM clustering to estimate subgrouping of a given disease code from clinical cases. Second, it decomposes the original datasets into datasets of subgroups by using granular homogenization. Thirdly, clinical pathway generation method is applied to the datasets. Fourthly, classification models of subgroups are constructed by using the analysis of discharge summaries to capture the meaning of each subgroup. Finally, the clinical pathway of a given disease code is output as the combination of the classifiers of subgroups and the the pathways of the corresponding subgroups. The proposed method was evaluated on the datasets extracted hospital information system in Shimane University Hosptial. The obtained results show that more plausible clinical pathways were obtained, compared with previously introduced methods.
CLINICAL AND MICROBIOLOGICAL SUBSTANTIATION OF TOPICAL APPLICATION OF SORPTION HYDROPHILIC/HYDROPHOBIC COMPOSITION BASED ON NANOSILICA IN THE TREATMENT OF PATIENTS WITH BURNS
Authors: Chornopyshchuk R.M. , Nagaichuk V.I. , Gerashchenko I.I. , Nazarchuk O.A. , Sidorenkov S.A. , Chepliaka O.M. , Sidorenko L.A.
Published: October 2021

Relevance.One of the promising methods of treatment of patients with burns is the local use of sorption agents with antimicrobial properties.

Objective: experimental study of antimicrobial properties and clinical evaluation of the effectiveness of local use of a new sorption composition based on nanosilica in the complex treatment of patients with burns.

Materials and methods. The suggested sorption nanocomposition included highly dispersed silicon dioxide, polymethylsiloxane, decamethoxine, metronidazole.

The experimental study involved the study of the antimicrobial properties of the sorption nanocomposition and antimicrobial agents which are part of it.

The clinical material consisted of the results of examination of 42 patients with IIab-III degree burns with an area of 10-30% of the body surface. Depending on the tactics of local treatment, patients were divided into 2 groups: after early necrectomy, xenodermoplasty, the wound surface of the patients in the main group (n = 20) was treated with a solution of decamethoxine in combination with the same sorption powder. Treatment in the comparison group (n = 22) was similar except the use of sorption drugs. The examination included visual inspection of the injured area in combination with microbiological monitoring of the wound contents on the 3rd,7th,14th day.

Results. The obtained results confirmed the sufficient antimicrobial potential of the studied sorption nanocomposition, the properties of which are not inferior to the existing antiseptics for museum and clinical strains of microorganisms and fungi.

Signs of a more favorable wound healing process of the patients in the main group were observed: faster wound cleaning, less inflammatory reactions and much shorter preparation of wounds for grafting.

Conclusions. The obtained results convincingly indicate the effectiveness of a multicomponent composite based on nanosilica with antimicrobial components in a comprehensive treatment of patients with burns.
MACHINE LEARNING ALGORITHMS IMPLEMENTATION IN THE HEALTHCARE SYSTEM AS A PROSPECTIVE AREA FOR SCIENCE, HEALTHCARE, AND BUSINESS
Authors: Vasylevkyi Valerii , Stepanov Ihor , Koval Roman , Soputnyak Mariya , Liutianska Nataliia , Sheyko Vladislav , Stavnychyy Taras
Published: October 2021

Relevance. The current state of medicine is imperfect as in every other field. Some main discrete problems may be separated in diagnostics and disease management. Biomedical data operation difficulties are a serious limiting factor in solving crucial healthcare problems, represented in the statistically significant groups of diseases. Accumulation of life science data creates as possibilities as challenges to effectively utilize it in clinical practice. Machine learning-based tools are necessary for the generation of new insights and the discovery of new hidden patterns especially on big datasets. AI-based decisions may be successfully utilized for diagnosis of diseases, monitoring of general health, prediction of risks, treatment solutions, and biomedical knowledge generation. Objective. To analyze the potential of machine learning algorithms in healthcare on exact existing problems and make a forecast of their development in near future. Method. An analytical review of the literature on keywords from the scientometric databases Scopus, PubMed, Wiley. Search depth 7 years from 2013 to 2020. Results. Analyzing the current general state of the healthcare system we separated the most relevant problems linked to diagnostics, treatment, and systemic management: diagnostics errors, delayed diagnostics (including during emergencies), overdiagnosis, bureaucracy, communication issues, and "handoff" difficulties. We examined details of the convenient decision-making process in the clinical environment in order to define exact points which may be significantly improved by AI-based decisions, among them: diagnosis of diseases, monitoring of general health, prediction of risks, treatment solutions, and biomedical knowledge generation. We defined machine learning algorithms as a prospective tool for disease diagnostics and management, as well as for new utilizable insights generation and big data processing. Conclusion. Machine learning is a group of technologies that can become a cornerstone for dealing with various medical problems. But still, we have some problems to solve before the intense implementation of such tools in the healthcare system.
Report of the Board of Directors to the Congress of Colombia - March 2021
Authors: Carrasquilla Barrera Alberto , Soto Losada Carolina , Steiner Sampedro Roberto , Villamizar Villegas Mauricio , Taboada Arango Bibiana , Villar Gómez Leonardo
Published: October 2021

In compliance with Act of Congress 31/1992, Article 5, the Board of Directors of Banco de la República hereby submits to the Congress of the Republic of Colombia a detailed report on the measures that Banco de la República has taken in the emergency situation generated by Covid-19 and presents the macroeconomic results for 2020 and the outlook for 2021 for its consideration. Furthermore, the breakdown of the Foreign Reserves and their performance, the financial position of the Bank and its forecasts, and the Bank’s Cultural management are described.
Expression pattern of MRPS18 family genes in gliomas
Authors: Kovalevska L.M. , Malysheva T.A. , Kalman S.S. , Rozumenko A.V. , Verbova L.V. , Rozumenko V.D. , Kashuba E.V.
Published: October 2021

Summary. Aim: To assess expression patterns of MRPS18 family genes in glioblastoma tissues and glioma cell lines. Materials and Methods: Expression of MRPS18 family genes was analyzed by quantitative polymerase chain reaction in glioma cell lines and glioblastoma specimens. A bioinformatic analysis of the publicly available data on the expression of these genes was also provided. Results: The genes of MRPS18 family show different expression patterns in glioblastomas and glioma cell lines. The highest levels of expression were found for MRPS18-2 at mRNA and protein levels in both glioblastomas and glioma cell lines; the lowest — for MRPS18-1 at mRNA level. Conclusions: The elevated levels of relative expression of the MRPS18-2 gene are characteristic for glioma tumor tissues and cell lines.
ESR1 gene variants affect FSHR-depended risk of fibrocystic mastopathy in infertile women
Authors: Kornatska A.G. , Rossokha Z.I. , Fishchuk L.Ye. , Dubenko O.D. , Medvedieva N.L. , Flaksemberg М.А. , Chubei G.V. , Popova O.F. , Gorovenko N.G.
Published: October 2021

Summary. Background: The infertile women have an increased risk of developing benign and malignant tumors, in particular, breast cancer. Most studies have examined the role of gene variants in the risk of developing breast cancer, but there is little evidence of genetic risk factors for benign tumors. Aim: To assess the combined genetic risk of developing mastopathy in women with FSHR (rs6165, rs6166) and ESR1 (rs9340799, rs2234693) gene variants. Materials and Methods: The study included 87 infertile women (45 with concomitant fibrocystic mastopathy and 42 without mastopathy). Results: For rs9340799 and rs2234693 variants of the ESR1 gene, we did not find any significant differences in the distribution of genotypes in infertile women with or without mastopathy. In patients with mastopathy, there was a reliable increase in the frequency of 307Ala/Ala and 680Ser/Ser genotypes of FSHR gene (χ2 = 6.39, p = 0.012, OR = 4.49 (1.48–13.65)) as compared to patients without mastopathy. In the presence of 307Thr/Thr and 680Asn/Asn genotypes of the FSHR gene, a 4.88-fold reduction of mastopathy risk (χ2 = 8.06, p = 0.005, OR = 0.21(0.07–0.59)) was observed. The frequency of the FSHR and the ESR1 genotypes combinations — 307Thr/Thr+680Asn/Asn+351AG+397TC was significantly decreased in patients with mastopathy. Conclusions: Our study did not find an association of ESR1 gene variants with the risk of developing of mastopathy in infertile women although heterozygous variants of the ESR1 gene enhanced the “protective” effect of FSHR gene variants and reduced the risk of mastopathy.
The hydronyms of the Labau, Lämäδ and similar isoglosses in the Ural-Altaic and other languages
Authors:   Institute of History, Language and Literature, Shamil Nafikov
Published: October 2021

The article is a study of the origin of Bashkir hydronyms with anlaut L-, (Labau, Lämäz, and a number of others). Against the background of extensive comparisons of similar ISSN (print)2664-5157 Turkic Studies Journal 2021, Volume 3, Number 364Гидроним Лабау, Ләмәз и подобные изоглоссы в урало-алтайских и других языках hydronyms and appellatives from the Turkic, Altaic, and other Eurasian languages. The author considers several versions of the said hydronyms viz possible origin from the Turkic, Altaic, Uralic or Euroasiatic languages at large. The stem and/or root of Bashkir hydronyms of the Lämäz type may be cognate with such hydronims as Laba in Poland > the Elbe in East Germany, -lej ‘a small river’ in the Volga Finnie languages and with a fair number of similar names of water objects in Europe, Asia and beyond. So, convergence with many of the same-root names of water bodies from several dozen languages and/or dialects is proposed. A large amount of material from the dialects and subdialects of the Bashkir language is involved. A conclusion is proposed about the very great antiquity of the hydronymy containing the anlaut L- in the bases of the LVC phonomorphological type. The answer to the question posed in the article’s title can hardly be definitive, as much further research is needed to clarify many points.
Review of the collective monograph
Authors:   L.N.Gumilyov Eurasian National University, Каirzhanov Аbay Каirzhanovich
Published: October 2021

Рецензируемая монография написана в рамках проекта МОН РК АР 05131798 «Сохранение и развитие этнического культурного наследия кыпчако-огузских народов в условиях современного Казахстана», посвященная истории, языку, этнокультуре кыпчакских и огузских народов Республики Казахстан. В этой книге дается квантитативная характеристика численности исследуемых народов в динамике исторических и современных переписей, на мой взгляд, удалось раскрыть исторические, культурные, общественно-политические причины и условия их миграции в Казахстан, среди которых отмечается насильственная депортация народов на территорию Казахстана в 1944 году во время Великой Отечественной войны. Авторы особое внимание уделяют социокультурным вопросам современных кыпчако-огузских народов, проблеме их расселения и описываются места их обитания, раскрываются вопросы этнической идентификации, созданию брачных союзов, вероисповеданию и занятости.
The Options and Limitations of the Brain Fingerprinting Lie Detection Method in the Criminal Proceeding
Authors: Budaházi Árpád , Fantoly Zsanett , Kakuszi Brigitta , Bitter István , Czobor Pál
Published: October 2021

The aim of this study is to introduce the new lie detection method of brain fingerprinting already introduced in the United States of America. According to some scholars, the method of a brain-focused instrumental credibility examination of testimonies still unknown in Hungary is highly reliable, establishing their concept on their belief that the human brain does not lie. First of all, we shall examine the possibilities lying in the measure, and second of all, we shall introduce the doubts causing the delay of its admission in Hungary.
Política Nacional de Saúde e a Educação Médica Brasileira
Authors: Kligerman Jacob
Published: October 2021

Conferência Magna proferida na Conferência Internacional sobre Educação Médica – Ano 2000 – Academia Nacional de Medicina – Rio de Janeiro – 25 a 28 de outubro de 2000.
Linfoma não-Hodgkin de Pequenas Células não-Clivadas, Tipo Burkitt com Apresentação Clínica de Hipercalcemia - Relato de Caso
Authors: Nogueira José Otho , Ribeiro Neto Carlos da Costa , Pinheiro Ronald Feitosa , Costa Eduardo Leite Vieira , Pontes Neto Octávio Marques
Published: October 2021

Neste artigo, os autores apresentam um caso de uma paciente de 60 anos que procurou um serviço de emergência com quadro de vômitos incoercíveis e que apresentava nos exames de urgência uma hipercalcemia de 19g/dL. Após estabilização do cálcio sérico com hidratação, corticóide e bifosfonatos, a elaboração diagnóstica revelou um linfoma de pequenas células não clivadas, tipo Burkitt, um linfoma não-Hodgkin que raramente tem sido associado a essa apresentação inicial. Os autores fazem, ainda, uma breve revisão da literatura sobre as neoplasias mais comumente associadas à hipercalcemia.
Tumor Neuroectodérmico Primitivo na Infância: Relato de 13 Casos e Revisão da Literatura
Authors: Costa Cecília M. L. , Rondinelli Patricia , Camargo Beatriz de
Published: October 2021

Proposta: A proposta desse estudo é a análise retrospectiva dos pacientes com diagnóstico de tumor neuroectodérmico primitivo (PNET), admitidos no Departamento de Pediatria do Hospital do Câncer no periodo de 1989 a 1996. Pacienttes e métodos: Todos os 13 pacientes portadores de PNET foram analisados retrospectivamente utilizando uma ficha para obtenção dos dados epidemiológicos clínicos, terapêuticos e seguimento de cada paciente. Resultados: A cirurgia foi a primeira abordagem terapêutica em 2 pacientes. Quimioterapia foi administrada em 12 pacientes e radioterapia em 2. Dos 13 pacientes 5 estão vivos em seguimento médio de 48 meses após o término do tratamento. Conclusão: A análise dos 13 pacientes com PNET e revisão da literatura demonstram a agressividade desse tumor. Devido a raridade dessa patologia, estudos multiinstitucionais, podem ter papel importante para análise de fatores prognósticos e consequente abordagem terapêutica.
News values as evaluation. Main naming practices in Violence Against Women news stories in contemporary Spanish newspapers: El País vs. El Mundo (2005-2010)
Authors: Santaemilia José
Published: October 2021

Violence Against Women (VAW) is a very sensitive, and highly ideological, topic in the Spanish society, as well as in Western societies generally. In Spain, media accounts of VAW are very closely related to two quality newspapers, El País and El Mundo, providing a variety of naming practices for VAW, with differing ideological and evaluative implications. In this paper, I compare and contrast these two dailies in their use of the three main naming practices —violencia de género ‘gender-based violence’, violencia doméstica ‘domestic violence’ and violencia machista ‘male violence’— used in VAW news. To do so I resort to the news values approach proposed by Bednarek and Caple (2012, 2014, 2017), which involves paying attention to the combined insights from both Corpus Linguistics and Critical Discourse Analysis (cf. Baker et al. 2008, Partington et al. 2013).
Leadership in Information Technology: Leadership theories, perspectives and ethical dilemmas
Authors:   Kennesaw State University, Malcom Douglas
Published: October 2021

This paper will describe various leadership theories and how they were formed, current leadership perspectives for information technology (IT) and the impact they can have on an IT workforce due to negative impressions and conditions. It will then relate current ethical issues faced by Information Technology to the key driving forces behind IT today along with detailing the current ethical issues faced by IT Leadership. Finally it will recommend some future research to help IT Leadership navigate the ethical and leadership issues faced today and to prepare for the future issues that will appear as technology advances.
THEORY OF ACCOUNTING IN THE CONDITIONS OF FORMATION OF THE GLOBAL ECONOMY AND INFORMATIZATION OF SOCIETY
Authors:   Central Ukrainian National Technical University, Kononenko Lesya , Yurchenko Oksana ,   Central Ukrainian National Technical University, Gai Oleksandr ,   Central Ukrainian National Technical University
Published: October 2021

At the present stage, there is a discrepancy between the existing theoretical foundations of accounting to the requirements of the modern global economy and the informatization of society. The purpose of the article is to establish the compliance of the theoretical foundations of accounting with the requirements of the modern global economy and the processes of informatization of society. The research methodology is based on general scientific methods of cognition: historical, logical, systemic, induction, deduction, analysis, synthesis. Today, humanity is at the origins of the Fourth Industrial Revolution, which is based on the digital economy. The use of digital technologies in accounting today leads to an increase in its quality characteristics, to improve the quality and efficiency of the enterprise management process. The development and formation of the global economy primarily involve the existence of a single information base, which necessitates the consistency of terminology in different scientific segments of a single information space. Today, the economic sciences are characterized by significant uncertainty in terminology and unjustifiably using parallel terminology. This necessitates the provision of accounting theory with an appropriate terminology that would be consistent with other scientific segments. The universal terminology will strengthen the relationship of accounting with the functions of analysis, planning, control, etc. The accounting information system is a subsystem of a higher-level system and as a part of the whole is incomparably more significant than itself. At one time, prominent researchers of capitalism of the XIX century. K. Marx and M. Weber, each from different ideological positions, came to the unequivocal conclusion: the development of capitalism is impossible to imagine without adequate accounting. Just as the development of double-entry bookkeeping was conditioned by the development of capitalism, the existence and development of the global economy is impossible without transforming the theoretical foundations of accounting. The prospect of further research is the adaptation of the theoretical foundations of accounting to the use of digital technologies.
PRIORITIES FOR IMPROVING THE EFFICIENCY OF TAX CONTROL IN UKRAINE
Authors:   Zhytomyr Polytechnic State University, Aleksandrova Maryna , Dovgaliuk Vita ,   Zhytomyr Polytechnic State University
Published: October 2021

The article reveals the essence of tax control and establishes the relationship between taxpayers and regulatory authorities. The purpose of the article is to substantiate the theoretical provisions and develop practical recommendations for the development of tax control in Ukraine. The methodological basis is a set of general scientific principles, methods of scientific knowledge, methods and techniques used in the research process. The peculiarities of the formation of tax relations were revealed and the interest of both parties in the conflict-free existence of economic interests was established. Also considered tax control from the standpoint of the source of tax risks for each of the subjects of taxation, considered the features of the response of taxpayers to tax risks in the event of changes in tax control procedures. The analysis of the effectiveness and efficiency of tax inspections indicates that the receipt of accrued and agreed with taxpayers monetary liabilities is not complete, which negatively affects the amount of revenues to the revenue side of the budget and overspent resources of the state and taxpayers for such controls. The control and revision measures were carried out, which were carried out and aimed at identifying and working out the facts of violation of the current legislation related to legalization (laundering) of proceeds from crime and other offenses. As a result of the study, it was noted that the effective organization of tax control should help reduce the tax risks of the state and taxpayers, and, accordingly, by reducing tax offenses, and increase tax revenues to the state budget. The practical significance of the obtained results lies in the possibility of implementing conclusions and proposals on theoretical, organizational and methodological support for the development of tax control through the use of new digital technologies and other tools for monitoring the completeness of tax liability of taxpayers. The use of the results is possible in determining the further directions of development of tax control in the context of digitalization, in the development of methodological support for control measures during the implementation of all forms of tax control.
ROLE OF THE CREDIT CHANNEL IN THE MECHANISM OF MONETARY TRANSMISSION IN UKRAINE
Authors:   Banking University, Mishchenko Svitlana , Mishchenko Volodymyr ,   Banking University
Published: October 2021

The article provides a comprehensive analysis of the functioning of the credit channel of the monetary transmission mechanism in Ukraine in 2005–2020, defines its role, the main tasks and features of its use in the system of modern monetary regulation of the economy. It has been substantiated that the main task of managing the credit channel of the transmission mechanism is to increase the efficiency of monetary regulation by transferring monetary impulses from the central bank to the real sector of the economy in order to ensure economic growth. Criteria are determined, basic indicators are proposed and methods for assessing the effectiveness of the functioning of the credit channel of monetary transmission are improved. As a result of calculations, it was proved that in 2005–2020 in Ukraine, the credit channel of the monetary transmission mechanism had a positive effect on the growth rate of the monetary aggregate M3 and the growth rate of the real gross domestic product, while the increase in government bond yields and the share of non-performing loans had a negative impact on lending activity and the rate of lending to the economy. The main reasons for the low efficiency of using the credit channel were the deterioration of the financial condition of enterprises and households, a decrease in their creditworthiness, low demand for investment resources, a high proportion of non-performing loans, significant volumes of government bonds issued by the government and high credit risks, which made it difficult for the central bank to adopt effective decisions and constrained economic growth. The main directions of improving the management and increasing the efficiency of the functioning of the credit channel of monetary transmission in Ukraine on the basis of improving the credit and investment climate, improving the methodology for assessing credit risks, increasing the efficiency of monetary regulation and the implementation by the central bank of a monetary policy adequate to economic conditions have been identified. The forecast parameters and conditions for the effective functioning of the credit channel of the monetary transmission mechanism in Ukraine in the medium and long term are proposed.
PRICE STRATEGY OF FEA SUBJECTS IN UKRAINE: FEATURES OF FORMATION AND DEVELOPMENT PROSPECTS
Authors:   Lviv Politechnic National University, Chyrkova Yuliia , Kvasnytsia Vira ,   Lviv Politechnic National University
Published: October 2021

The purpose of the article is to study pricing strategies and develop measures to improve the pricing strategy of foreign economic activity on enterprises. Pricing strategy is one of the most important components of the entire enterprise management system, which can affect the main performance indicators of the enterprise. It is a plan for the formation and management of prices in order to remain competitive in the market and achieve the goals and objectives. The implementation of an effective pricing strategy is due to the need to make important pricing decisions in the long run that have an impact on the enterprise. The pricing strategy with a foreign economic orientation becomes especially decisive. In the context of export-import operations, it is important for Ukrainian enterprises, as subjects of foreign economic activity, to plan activities for the long term in order to remain competitive in the foreign market. Foreign economic activity of the enterprise creates the preconditions for its sustainable economic development through the expansion of its activities in international markets and the formation of new sources of income production resources, technologies and modern organization of production. Today in the field of pricing there are many problems that reduce both the efficiency of the economy and the effectiveness of pricing policy enterprises in particular. This necessitates a new approach to formation of the company’s pricing policy and formation of its pricing strategy. The following methods are used in the article: analysis and synthesis, generalization, coefficient and graphical method, comparison method and systematization methods. The result of the study is the formation of ways to solve existing problems in Ukrainian enterprises through introducing the price discounts accumulative system and implementing a combined strategy for the formation of export prices to increase efficiency of the enterprise foreign economic activity. The practical significance of the work lies in the developed measures to address the problems of pricing strategy, which were identified at the enterprises of Ukraine, engaged in foreign economic activity.
Creativity, Innovation and Promotion Variables as Determinants of Culinary Bussiness Success in OKU Regency
Authors: Sari Yunita , - Munajat , Permatasari Fifian
Published: October 2021

The objective of this research was to examine the effects of creativity, innovation, and promotion variables as determinants of culinary business success in the Ogan Komering Ulu (OKU) regency. The research design was survey research with a quantitative approach. The population of this research consisted of culinary businesses in the OKU regency. The analytical method used was multiple regression. The conclusion of this research showed that creativity, innovation, and promotion variables had significant effects on the success of the culinary business in the OKU regency. This research focused on creativity, innovation, and promotion as independent variables and business success as the dependent variable
INFORMATION TECHNOLOGIES IN ACCOUNTING AND RELATED SECURITY RISKS
Authors: Chekh Nataliia , Konoplina Olena , Mizik Yuliya
Published: October 2021

Today, the business environment has become extremely dynamic due to rapid changes in information technology due to competition and the desire for efficiency. Designed to meet a wide range of economic requirements, new technologies offer flexibility, economies of scale, mobility and greater accuracy. The field of accounting is subject to this new era of change. The era of the Internet of Everything (IoE) is reshaping the profession of accountant according to the current needs of organizations. Artificial intelligence and process automation take on redundant and repetitive tasks performed by professionals, creating space for more complex activities such as analysis and business consulting. The article considers the main modern information technologies and the possibilities of their use in accounting. With the use of information technology, more opportunities have opened up in the field of accounting. The purpose of the article is to analyze the use of modern information technology in accounting, to study the features of their implementation and related risks for the company. Technological determinants of the development of the organization of accounting are: the spread of mobile communications; improving the provision of Internet access services; software development; conversion of smartphones, tablets into integrated devices, their active use in the workplace of accounting staff.The main advantages of such technologies as cloud computing platforms, big data, data mining and mobile technologies are identified. The main threats associated with the use of these technologies have also been identified. It is determined that new technologies, as well as the need for real-time reporting make changes in the profession of accountant. Novice accountants may lack the knowledge to efficiently obtain and process large amounts of data. This is due to the fact that the existing curricula of accounting faculties in Ukraine are not sufficiently focused on new technologies, such as cloud computing, Big Data or data mining. As a result, it can be difficult for accountants to secure confidential information using the latest technology.
How Does the COVID-19 Pandemic Affect Transport-Related Diesel Consumption in the U.S.?
Authors: Wu Xinyi , Zhou Yan , Lu Zifeng , He Xin
Published: October 2021

Understanding how energy usage reacts to the COVID-19 pandemic is essential to making strategic policy decisions. This study aims to quantify the pandemic’s influences on diesel consumption and explore the potential causes of the differences across regions. We found various levels of reduction in diesel consumption at the state level during the pandemic in the U.S. Many factors, including COVID-19 cases and commodities being moved, are associated with these reductions. In particular, at the state level, more truck/train shipping of minerals, coal, and forest products associates with fewer truck activities and greater decreases in diesel consumption.
Google Workspace as a b-learning platform. Analysis of the perceptions of the Degrees in Communication
Authors:   Centro Universitario San Isidoro, España, Martín-Herrera Inmaculada , Micaletto-Belda Juan Pablo ,   Centro Universitario San Isidoro, España, Polo Serrano David ,   Centro Universitario San Isidoro, España
Published: October 2021

This article has investigated the perceptions about the educational use of the Google Workspace (formerly Google Suite) of a group of 131 students who are studying Communication Sciences and Digital Communication degrees at a University Center in the province of Seville, Spain. The main objective of the research was to collect and analyse the educational experience and the competences developed by these students with this software suite in university education. To do so, a descriptive research was designed based on a quantitative and qualitative analysis using an online questionnaire. The results showed that these university students value favourably the interface and services provided by this platform, especially Meet, Documents, Gmail, Classroom and Presentations. However, they perceive that other applications, such as Keep, Jamboard or Tasks, are not very useful. In short, blended learning models proposed by Google Workplace have proven useful in the university field, and that students have adapted adequately to the new learning environment.
Design and validation of an electronic teaching case on critical thinking
Authors:   Universidad Nacional Autónoma de México, Morales Bautista María Luisa , Díaz Barriga Arceo Frida ,   Universidad Nacional Autónoma de México
Published: October 2021

Based on the teaching case methodology, a case was designed and validated in an electronic format (e-case), about critical thinking in relation to violence in the teenage couples. The design considers a situation-problem in the form of narrative, exposed to the high school students, who through a series of questions and activities proceed to the analysis, take a position and propose solutions. The e-case was carried out on HTML5 using WIX.com, and contains the following entries: introduction, characters, story, questions, activities, evaluation and contact. This article reports the techno-pedagogical design and the validation by experts and with the target population. The results were favorable and coincident regarding the content, didactic treatment and design of the website. Likewise, guidelines are provided for the design of an e-case and validation model for those who wish to get involved in this strategy.
Lectura del paisaje urbano de la Colonia Americana de Guadalajara
Authors:   Universidad de Guadalajara, Torres López Yolanda
Published: October 2021

Así como un libro está compuesto de un conjunto de palabras y oraciones que intentan decir algo con sentido, las edificaciones son textos compuestos de un lenguaje arquitectónico cuyo significado va más allá de la imagen, pues involucran un uso y una disposición. El propósito de esta discusión es hacer una reconstrucción semiótica del barrio como un conjunto de obras arquitectónicas que conforman un paisaje urbano: espacios de integración y espacios de tránsito. El presente estudio se realiza desde la antropología cultural, por lo que es importante aclarar que no parte exclusivamente del urbanismo y la arquitectura. El paisaje urbano está integrado por edificaciones, manzanas, calles, avenidas, parques y plazas. Este stock edilicio conforma un texto. La selección del corpus de estudio en este caso no está determinada por las divisiones administrativas de los barrios o colonias, sino que toma como referentes hitos, espacios y funciones de la ciudad que marcan límites y lugares de destacada significación cultural ya sea por su tradición o valor patrimonial o porque constituyen espacios de prácticas sociales significativas.
Educación para la paz. Una mirada hacia el modelo para Jalisco
Authors:   Universidad de Guadalajara, Preciado Rodríguez Teresa Magnolia
Published: October 2021

Hablar de los retos de la educación en México puede significar varias líneas, sin embargo, nos referiremos a lo señalado por el artículo 3º de la Constitución Federal, que reconoce como derecho fundamental el acceso a la educación, la cual deberá entre otras características fomentar la cultura de paz. La Ley de Educación del Estado de Jalisco, reformada recientemente pretende hacer efectiva esta garantía al señalar en su artículo 13 entre sus fines “Formar a los educandos en la cultura de la paz, en este sentido, el objetivo de este trabajo es identificar los modelos y alcances educativos que permitirán incorporar esta visión de cultura de paz en la educación que se imparta en Jalisco. Para este trabajo nos enfocaremos en Jalisco, siendo uno de los estados con peor porcentaje de jóvenes realizando estudios, este estudió se enfocará en el análisis del modelo educativo que la entidad propone. Este trabajo tiene como objetivo comparar el trabajo que al día de hoy se realiza, en comparación a los modelos que son utilizados en el mundo y otros estados.
Study of polysynaptic reflex excitability and somatosensory evoked potentials in patients with myofascial pain syndrome
Authors: Safiullina A. A. , Safiullina G. I. , Yakupov R. A.
Published: October 2021

Introduction. Myofascial pain syndrome (MFPS) is one of the most common pathologies of the musculoskeletal system that causes chronic pain. This type of pain reaches its peak in middle-aged people; women get sick 2,5 times more often than men. The disease leads to significant disability; it is not only a medical but also a social problem. Atthe same time, a number of authors still note the low clinical efficacy of the applied therapy regimens. In this situation there is in demand the further study of the MFPS pathogenesis, in particular, the clinical and electroneurophysiological characteristics of this pathology, in order to search for new, including pathogenetically proved, treatment methods.

The aim of the research was to study the relationship between the indicators of the blinking reflex and somatosensory evoked potentials in patients with active and latent forms of MFPS.

Materials and methods. In order to study the neurophysiological aspects of MFPS, a comprehensive clinical and electroneurophysiological examination was carried out in 92 patients of working age, including 78 women and 14 men, whose average age was 48,1±9,3) years, suffering from MFPS of the scapular area. The patients were subdivided into subgroups depending on the prevalence and severity of pain manifestations: the first subgroup — with an active form (58 people, 63 %), the second subgroup — with a latent form of MFPS (34 people, 37 %). The control group was formed from conditionally healthy volunteers in the amount of 35 people, comparable to the main group by age and sex.

Results. The comparing of the study results, taking into account polysynaptic reflex excitability and the data of somatosensory evoked potentials, revealed the significant positive correlations of the indicators. The obtained results allowed to assess the excitability of spinal cord motor neurons as well as suprasegmental structures in MFPS, involved in the implementation of pain syndrome.

Conclusion. The use of clinical electroneurophysiology methods makes it possible to assess the functional state of the CNS structures involved in the analysis of nociceptive afferentation. In the active form of MFPS, an increase in the excitability of stem and thalamic structures was mainly determined, which could potentially indicate the activation of adaptive processes on the one hand, and on the other hand, the predisposition of neuronal networks to a state of arousal. In the latent form of MFPS, a multidirectional change in reflex excitability was observed.
Rencana Kebijakan dan Program Pembangunan Hortikultura Lahan Kering untuk Provinsi Sumatera Utara: Sudah Tepatkah?
Authors: Juhandi Dany , Purba Ardian Elonard
Published: October 2021

Konsumsi buah-buahan dan sayuran meningkatkan permintaan komoditas hortikultura tetapi pertambahan produksi komoditas hortikultura lebih kecil dibandingkan dengan pertambahan permintaannya, sehingga perlu dilakukan impor untuk memenuhi kebutuhan konsumsi tersebut. Pemerintah pada tahun 2019 merencanakan komoditas hortikultura untuk setiap provinsi di Indonesia. Tujuan penelitian ini yaitu menganalisis komoditas hortikultura unggulan lahan kering di Provinsi Sumatera Utara, menganalisis spesialisasi dan lokalisasi komoditas hortikultura lahan kering di Sumatera Utara, dan membandingkan komoditas hortikultura prioritas lahan kering di Provinsi Sumatera Utara. Data sekunder yang digunakan dalam penelitian ini mulai dari tahun 2017 – 2019. Analisis data yang digunakan yaitu Location Quotient (LQ), Spesialization Quotient (SQ) dan Localization Quotient (LoQ). Hasil penelitian menunjukkan komoditas hortikultura unggulan lahan kering didominasi oleh bawang merah, cabai, mangga, durian, pepaya, dan lengkuas di Kabupaten Tapanuli Utara, Toba Samosir, dan Dairi. Ada beberapa komoditas hortikultura lahan kering memiliki keunggulan komparatif dan produksinya tidak terlokalisasi seperti komoditas mangga, durian dan cabai di Kabupaten Batu Bara dan Labuhan Batu Selatan, sehingga lima puluh persen komoditas hortikultura lahan kering menjadi komoditas prioritas.