bluuebunny/crossref_metadata_2025 huggingface dataset:
Perubahan Sosial Masyarakat di Desa Bona, Kecamatan Blahbatuh, Kabupaten Gianyar Pada Masa Pandemi Covid-19
Authors: Pidada Ida Bagus Astika , Mayuni Anak Agung Inten , Mileh I Nengah
Published: January 2022

Desa Bona terletak di Kecamatan Blahbatuh, Kabupaten Gianyar. Masyarakat desa ini hidup dari sektor pertanian yang memberikan manfaat cukup besar dan juga kerajinan lontar. Jenis-jenis kerajinan lontar yang diproduksi, seperti: tas, topi, dan lain-lain. Kerajinan lontar menjadi salah satu peluang yang cukup besar bagi masyarakat Desa Bona yang diminati oleh wisatawan asing. Hasil kerajinan ini dipasarkan di beberapa lokasi, seperti: Ubud, Nusa Dua, Kuta, Tabana, and sebagainya. Semenjak terjadinya pandemi covid-19 kerajinan lontar banyak mengalami penurunan dalam penjualan. Berdasarkan kasus ini, mahasiswa KKN Universitas Warmadewa dipandang perlu untuk melakukan pemberdayaan UMKM di desa ini. Hasil kerajinan lontar dipasarkan dan dirubah dengan sistem konvensional menjadi sistem online oleh mahasiswa dengan tujuan supaya produk industri rumah tangga lebih dikenal luas oleh masyarakat dan pendapatan meningkat. Selain itu, pelaksanaan KKN di desa ini mahasiswa berpartisipasi mencegah penyebaran pandemi covid-19 dengan membagikan masker gratis di tempat-tempat keramaian. Kemudian, mahasiswa melakukan kegiatan lapangan, seperti: bersih-bersih di areal pura dengan memberikan bantuan tong sampah dan serok sampah. Mahasiswa KKN Universitas Warmadewa melakukan aktifitas lainnya, seperti: sosialisasi pernikahan dini, lomba mewarnai, lomba poster, lomba busana adat serta membantu siswa belajar menggunakan aplikasi zoom dan google classroom. Kegiatan online KKN PPM di Desa Bona, Kecamatan Blahbatuh, Kabupaten Gianyar khususnya setiap program yang diberikan oleh mahasiswa mendapat sebuah apresiasi yang baik oleh masyarakat sehingga membuat kegiatan ini dapat berjalan lancar.
KAJIAN RESIKO GEMPA DENGAN PENDEKATAN METODE RAPID VISUAL SCREENING (RVS) FEMA 154 DAN 3D RESPONSE SPEKTRUM TERHADAP GEDUNG UNIVERSITAS WIJAYAKUSUMA PURWOKERTO
Authors: Novi Andhi Setyo Purwono  , Iwan Rustendi  , Roesly Sakban  , Ajeng Purba Kencana
Published: January 2022

Gempa merupakan salah satu yang terjadi akibat kejadian pergeseran tiba-tiba dari lapisan tanah di bawah permukaan bumi. Purwokerto sebagai kota Kabupaten Banyumas adalah kota yang saat ini berusaha berkembang seperti halnya kota-kota besar lainnya yang ada di Indonesia. Gedung perkuliahan merupakan fasilitas pelayanan umum dalam hal pendidikan terhadap masyarakat Sebagai gedung perkuliahan harus mampu memberikan kelayakan dan kenyamanan sehingga aktivitas di dalam dan luar gedung perkuliahan menjadi nyaman. Penelitian ini bertujuan meninjau kerentanan beberapa bangunan yang terdapat pada Universitas Wijayakusuma terhadap gempa bumi. Untuk mengetahui kelayakan bangunan tersebut pendekatan analisa yang dilakukan dengan menggunakan metode RVS yang terdapat pada FEMA 154, selain itu perhitungan pembebanan dilakukan dengan pemodelan SAP 2000 dengan metode 3D Response Spektrum. Hasil penelitian menunjukkan bahwa gedung bertingkat pada Universitas Wijayakusuma Purwokerto aman terhadap gempa apabila dikaji dengan metode RVS, sedangkan apabila dikaji dengan metode 3D response spectrum yang sesuai dengan SNI 1726-2019 gedung-gedung tersebut kurang aman untuk waktu getar alami fundamental, tetapi untuk pembebanan ketiga gedung tersebut aman.
ANALISIS KELAYAKAN EKONOMI PADA PEMBANGUNAN PERKANTORAN TOWER POROS MARITIM SURABAYA
Authors: Eka Nurus Sakinah  , I Nyoman Dita Pahang Putra  , Anna Rumintang
Published: January 2022

Meningkatnya penduduk dan berkembangnnya bisnis di Surabaya menjadikan perusahaan besar membutuhkan ruang untuk karyawannya. Menilai suatu karakteristik dari sebuah pembangunan proyek harus melakukan studi kelayakan. Salah satu studi kelayakan yang dilakukan adalah dengan melakukan analisis kelayakan ekonomi. Analisis ini dilakukan untuk memastikan bahwa proyek tersebut layak dilakukan secara aspek ekonomi. Tujuan penelitian ini untuk mengetahui seberapa besar keuntungan dan biaya yang didapatkan dan sejauh mana kelayakan ekonominnya. Proyek yang akan diteliti pada penelitian ini adalah perkantoran Tower Poros Maritim Surabaya. Kemudian kelayakan pada proyek pembangunan perkantoran ini didasarkan pada perhitungan Benefit Cost Ratio (BCR), Net Present Value (NPV), Internal Rate of Return (IRR), dan Return on Investment (ROI). Hasil analisis kelayakan ekonomi ini didapatkan nilai NPV positif sebesar Rp.32,995,643,307.00, nilai IRR sebesar 12.08%, ROI 15.76% dan BCR sebesar 3.2. Kemudian pengembalian investasi dihitung dengan aliran kas tahunan dengan jumlah tidak tetap didapatkan nilai jangka waktu 2 tahun 10 bulan 8 hari.
ANALISIS ALTERNATIF PERENCANAAN DIMENSI TEROWONGAN PENGELAK BENDUNGAN SIDAN
Authors: A. A. Ngr. Billy Narendra  , Cok Agung Yujana  , I Ketut Yasa Bagiarta  , Putu Aryastana
Published: January 2022

Kekurangan pasokan air di Provinsi Bali menyebabkan adanya rencana pembangunan Bendungan Sidan. Bendungan ini direncanakan dengan inti tegak dan dilengkapi dengan terowongan pengelak yang berfungsi membelokkan aliran sungai pada saat konstruksi bendungan dan mengontrol air yang berlebih. Terowongan pengelak di Bedungan Sidan awalnya dirancang dengan bentuk tapal kuda. Tujuan dari perencanaan ini adalah untuk merencakan dimensi alternatif terowongan pengelak Bedungan Sidan dengan penampang berbentuk lingkaran. Hasil analisis mendapatkan diameter terowongan pengelak adalah 5 m, dengan debit rancangan kala ulang 25 tahun sebesar 265.54 m3/dt. Tebal dinding terowongan direncanakan setebal 0.5 m dengan bahan terbuat dari beton bertulang, dimana pada tulangan utama digunakan 3D25-500 dan pada tulangan bagi digunakan D25-500.
Efficacy of Thermoformable Vacuum Head Cushion on Set-up Accuracy in IMRT of Head & Neck and Brain Tumors
Authors: ÖZKAN Emine Elif , ÖZSEVEN Alper , KAYMAK Zümrüt Arda
Published: January 2022

Aim: An effective immobilization is warranted to minimize set up deviations while treating head & neck (HN) and brain tumors with intensity modulated radiotherapy (IMRT).
In this study we evaluated the effectiveness of thermoformable vacuum head cushion (TVHC) on immobilization of these patients via weekly electronic digital port films (EDPF).
Material and Method: Twenty patients treated with IMRT for HN and Brain tumors were enrolled in the study. Thermoplastic mask with additional standard plastic head rest (n:10) in Group A or TVHC supporting the head and neck region (n:10) in Group B were used for immobilization. Weekly EDPF images were obtained on the linear accelerator. Set-up displacements in latero-medial, anteroposterior and cranio-caudal directions in these images were compared with variation data of first treatment.
Results: When each group was analyzed in terms of deviations in all 3 directions, deviations calculated in anteroposterior and craniocaudal directions were significantly higher for TVHC group (p:0.039 and p:0.002 respectively). Deviations >4mm in all three directions were also analyzed and similarly, higher rates of >4mm deviations were recorded for TVHC group in anteroposterior and craniocaudal directions (p:0.023 and p:<0.001 respectively) which of both were also statistically significant.
Conclusion:
We found that TVHC utilization in HN and brain IMRT for immobilization leads to significantly higher set-up deviations so future investigations with larger patient populations and evaluating set up accuracy via more sensitive alignments are needed to suggest TVHC for utilization in daily clinical practice.
Polikistik Over Sendromu ve Ağırlık Yönetimi Arasındaki İlişkinin İncelenmesi
Authors: SARIYER Esra Tansu , AKSU Burcu Merve
Published: January 2022

Polikistik over sendromu (PKOS) üreme çağındaki kadınlarda en sık görülen endokrin metabolik bozukluklardan biri olup tanımlanması zor heterojen bir hastalıktır. Etiyolojisi tam olarak bilinmemektedir. Semptomları hiperandrojenizm, hirsutizm, akne, amenore, oligoamenoredir. Prevalansı %6,5-8 arasında değişmektedir. Polikistik over sendromu obezite, insülin direnci, diyabet ve dislipidemi gibi metabolik bozukluklarla ilişkilidir. Polikistik over sendromunda insülin direnci prevalansı %50-75 aralığında değişmekle beraber, bu bireylerde diyabet başlangıç yaşı sağlıklı bireylere göre 10 yaş daha erkendir. Obezite genellikle abdominal obezite olarak görülür ve PKOS’lu kadınların yaklaşık %50’sini etkilemektedir. İnsülin direnci ve abdominal obezite PKOS’ta metabolik bozukluk gelişme riskini arttırmaktadır. Polikistik over sendromlu bireylerde birincil tedavi yaklaşımı tıbbi beslenme tedavisi ve egzersizi içeren yaşam tarzı müdahalesidir. Polikistik over sendromu tanılı kadınların izokalorik beslenme planı uygulamalarına rağmen PKOS tanılı olmayan kadınlara göre yüksek beden kütle indeksi (BKİ) değerine sahip olmaları ile birlikte sağlıklı BKİ aralığındaki kadınlarda da vücut yağ yüzdesi değerlendirmesine göre obezite görülebilmektedir. Bu nedenle, tıbbi beslenme tedavisi yaklaşımlarının vücut ağırlığı kaybını hedefleyici olması gerekmektedir. Tıbbi beslenme tedavisi olarak; şeker ve rafine karbonhidratların tüketiminin sınırlandırılması, düşük glisemik indeksli besinlerin tüketilmesi, doymuş ve trans yağ alımının azaltılması ile birlikte D vitamini, krom, inositol ve omega-3 yağ asitlerinden zengin yeterli ve dengeli bir beslenme önerilmektedir. Günlük alınan enerjinin %55’inin karbonhidratlardan, %15’inin proteinlerden sağlanması ile birlikte yağ alımının %30 ile sınırlandırılması önerilmektedir. Polikistik over sendromunda vücut ağırlığı kaybı ve kaybedilen ağırlığın korunması zorlaşmaktadır. Bu nedenle tıbbi beslenme tedavisinde diyete uyumun değerlendirilmesi önemlidir. Bu çalışmada PKOS tanılı kadınlarda yaygın olarak görülen obezite ve komorbid hastalıklar ile vücut ağırlığı yönetimi ilişkisi incelenmesi amaçlanmıştır.
Endodontik Tıp: Sistemik Hastalıkların Pulpal ve Periapikal Dokular ile İlişkisi
Authors: OCAK Jülide , KEÇECİ Ayşe Diljin
Published: January 2022

Endodontik enfeksiyonlar ile sistemik hastalıklar arasındaki çift yönlü ilişkiyi ele alan “Endodontik Tıp”, her geçen gün daha fazla önem kazanmaktadır. Sistemik hastalıklar endodontik enfeksiyonların patogenezini etkileyebilirken, endodontik enfeksiyonun da sistemik değişikliklere neden olabileceğini gösteren çok sayıda kanıt vardır. Diyabet, kardiyovasküler hastalıklar, renal ve romatoit hastalıklar ve hipoöstrojenemi gibi sistemik hastalıkların pulpa ve periodonsiyumda yarattıkları değişiklikler incelenmektedir. Bu değişiklikler, periapikal bölgede daha şiddetli bir kemik rezorpsiyonu ve enflamasyonun yanı sıra sistemik hastalığın ilerlemesi şeklinde de olabilir. 1800’lerden 1950’lere kadar oral enfeksiyonun sistemik hastalıkla direkt ilişkisini savunan fokal enfeksiyon teorisi nedeniyle diş ve tonsilla gibi organların uzaklaştırılması öneriliyordu. Bu durumun daha sonra kesin bir dil ile reddedilmesine karşın, yeni çalışmalar ışığında sistemik ve pulpal ilişkinin keskin sınırlarla ayrılamayacağı anlaşılmaktadır. Bu derlemenin amacı, sistemik hastalıklar ile endodontik enfeksiyon arasındaki çift taraflı ilişkiyi ortaya koyan literatürü analiz etmek ve bu bağlantıların sistemik sağlık durumu ile endodontik tedavi sonuçlarına nasıl etki edebileceğini belirlemektir.
Variations of Formation, Distribution and Communications of Median Nerve in Fetal Cadavers
Authors: ÖZTÜRK Kenan , CANDAN Büşra , DURSUN Ahmet , KASTAMONİ Yadigar , TUNALI Selçuk , ALBAY Soner
Published: January 2022

Objective: Variations of the median nerve (MN) are important for clinical and surgical approaches. In this study, it was aimed to determine the formation, distribution and communication of the MN in fetal cadavers.Material and Method: This study was carried out on 80 upper extremities obtained from 40 spontaneously aborted human fetuses (22 females, 18 males) aged between 18 and 40 weeks. Median, ulnar and musculocutaneous nerve (MSCN) and their branches were identified and distribution of their branches was determined. The distribution, formation and communications of the MN were examined. Results: In this study, it was seen that the MN was composed of three roots in the 6 (7.5%) of 80 upper limbs. It was also found that the MN innervated the flexor muscles of the arm in two extremities despite MSCN was present (2.5%). It has also been determined that the MN innervated the flexor muscles of the arm in one extremity where MSCN was absent (1.25%). In addition, communications between the MSCN and the MN was detected in 3 (3.75%) extremities. Finally, in our study, Martin-Gruber communication was found 3.75% while Marinacci communication was not determined. Conclusions: This study identified variations and communications of the MN by means of fetal cadaveric dissection. These variations will adversely affect the correct diagnosis and treatment planning in upper extremity injuries. Therefore, precise knowledge of the variations and communications of the MN will be useful for surgeons to avoid iatrogenic injuries during surgical interventions in this region.
Eritrosit Dağılım Genişliği ile Sabah Kan Basıncı Dalgalanması Arasındaki İlişki
Authors: BÜBER İpek , TÜRKÖZ Anıl , ADALI Mehmet Koray
Published: January 2022

Amaç : Eritrosit dağılım genişliği (EDG), kalp yetmezliği, koroner arter hastalığı ve akut miyokard enfarktüsü olan hastalarda olumsuz sonuçlarla ilişkilidir. Sabah kan basıncı dalgalanması (SKBD) fenomeni, sabahları kan basıncında (KB) belirgin bir artış olarak tanımlanır. Bu çalışmada, EDG ve SKBD arasındaki ilişkiyi araştırmayı amaçladık.Materyal ve Metod: Haziran 2019-Aralık 2019 tarihleri arasında ambulatuvar KB kaydı yapılan iki yüz seksen dokuz (289) hastanın verileri retrospektif olarak analiz edildi. Ambulatuar KB verileri ile SKBD hesaplanarak EDG ile ilişkisi araştırıldı. Bulgular: Eritrosit dağılım genişliği üst değerine göre (%16) SKBD değerleri karşılaştırıldı (sırasıyla %16'nın üzerinde ve %16'nın altında, (33.7±16.2; 28.1±11.5; p = 0.038*) her iki grup arasında istatistiksel olarak anlamlı bir fark mevcuttu. SKBD ile ilişkili parametreleri göstermek için yapılan çok değişkenli linear regresyon analizinde SKBD’nin EDG (p=0.03) ve ürik asit (p= 0.02) ile ilişkili olduğu bulundu.Sonuç: Çalışmamızda SKBD'nin EDG ile bağımsız olarak ilişkili olduğunu ve EDG %16'nın üzerinde olduğunda anlamlı olarak daha yüksek olduğunu gösterilmiştir. Yeni bir kardiyovasküler risk faktörü olan SKBD, olumsuz kardiyovasküler sonuçlarla bağlantılı olan EDG ile ilişkilidir. EDG’nin yüksek olması daha yüksek SKBD’yi gösterebilir. Ambulatuar KB değerlendirmelerinde sıklıkla ihmal ettiğimiz SKBD bir risk faktörü olarak değerlendirilmelidir ve tedavi konusunda hedef olup olmaması konusunda prospektif çalışmalara ihtiyaç vardır.
Lisansüstü Hemşirelik Öğrencilerinin Yenilikçi Özellikleri ile Araştırmaya Yönelik Farkındalıkları Arasındaki İlişki
Authors: KARAÇAY Pelin , YAZICI Özlem , KEBAPÇI Ayda
Published: January 2022

Amaç: Bu araştırmanın amacı, lisansüstü öğrencilerinin yenilikçilik özellikleri ile araştırmaya yönelik farkındalık ve tutumları arasındaki ilişki ve etkileyen faktörlerin belirlenmesidir.Materyal Metot: Tanımlayıcı ve ilişki arayıcı tipteki araştırma, bir vakıf üniversitesinin Hemşirelik Lisansüstü Programında kayıtlı, araştırmaya katılmaya gönüllü 226 öğrenci ile yapıldı. Araştırmanın verileri; öğrencilerin sosyo-demografik ve lisansüstü eğitim sürecine ilişkin özellikleri, Bireysel Yenilikçilik Ölçeği (BYÖ) ile Hemşirelik Öğrencilerinin Araştırmaya, Gelişmelere Farkındalığı ve Tutumu Ölçeği (HÖAGFTÖ)’nin yer aldığı veri toplama formu ile Qualtrics üzerinden oluşturulan bağlantı ile elektronik ortamda toplandı. Verilerinin analizinde; tanımlayıcı istatistikler, Kruskal-Wallis testi, Mann-Whitney U testi, Bonferroni düzeltmeli Mann-Whitney U testi ve Spearman Rho Korelasyon Analizi kullanıldı.Bulgular: Lisansüstü öğrencilerinin HÖAGFTÖ toplam puanları ile BYÖ toplam puanları (r=0,428), fikir önderliği (r=0,390), risk alma alt boyutları (r=0,436) arasında pozitif yönde, değişime direnç alt boyutu puanları arasında ise negatif yönde (r=-0,274) istatistiksel olarak anlamlı farklılık saptandı(p<0,01). Kadınların, araştırma görevlisi/öğretim görevlisi olarak görev yapanların, bilimsel yayınları okuyanların, bilimsel yayınları üç ayda bir okuyanların ve kanıta dayalı bilgilere ulaşabildiğini düşünenlerin HÖAGFTÖ ve BYÖ puanları istatiksel olarak anlamlı düzeyde yüksek bulundu. Sonuç: Lisansüstü öğrencilerinin bireysel yenilikçilik özellikleri ile araştırma farkındalık ve tutumları arasında orta düzeyde bir ilişki vardır. Lisansüstü öğrencilerinin BYÖ ve HÖAGFTÖ puanlarını etkileyebilecek ve çalışmada ele alınmayan faktörlerin araştırılması önerilir.
Ankilozan Spondilit Ön Tanılı Hastalarda HLA-B27 Sıklığı
Authors: HEKİMLER ÖZTÜRK Kuyaş , ÖZBAŞ Halil , TEPEBAŞI Muhammet Yusuf , KOŞAR Pınar
Published: January 2022

Amaç: Ankilozan spondilitin (AS) oluşumunda genetik faktörlerin önemli olduğu kabul edilmiştir. Hastalığın patogenezinde rol alan en önemli genetik faktörlerden birinin insan lökosit antijen (HLA)-B27 olduğu bilinmektedir. Bu çalışmada AS ön tanılı hastalarda HLA-B27 sıklığının tespit edilmesi ve hastaların demografik ve laboratuvar bulguları ile HLA-B27 arasındaki ilişkinin karşılaştırılması amaçlandı.Materyal-Metod: AS ön tanılı 64’ü erkek, 91’i kadın olmak üzere toplam 155 hasta çalışmaya dahil edildi. Hastaların poliklinik takip dosyaları geriye dönük taranarak demografik özellikleri, genetik soyağacı bilgileri, laboratuvar bulguları ve HLA-B27 gen analizi sonuçları kaydedildi. Hastaların HLA-B27 analizleri Real-Time PCR yöntemi ile yapıldı.Bulgular: Elde edilen bulgulara göre çalışmaya alınan AS ön tanılı hastaların 31’inde (%20) HLA-B27’nin pozitif olduğu saptandı. Erkeklerde HLA-B27 pozitifliği daha yüksekti (p=0,010). Yaş ortalaması cinsiyetler arasında fark göstermedi (p>0,05). HLA-B27 pozitif olanların yaş ortalaması negatif olanlara kıyasla anlamlı derecede düşüktü (p=0,047). Serum CRP ve sedimentasyon seviyeleri HLA-B27 pozitifliğinde belirleyici değildi (p>0,05). HLA-B27 pozitif olan hastalarda aile öyküsü olanlar olmayanlara kıyasla daha fazlaydı (p=0,000). Sonuç: AS semptomlarını taşıyan hastalarda HLA-B27 pozitiflik oranı literatürden farklı olarak düşük bulundu. Bu farklılığın, AS ön tanılı hastaların çalışmaya dahil edilmesi, farklı hasta popülasyonu, klinik varyasyonlar, farklı etnik köken ve farklı genetik ve/veya çevresel faktörlerden kaynaklanmış olabileceğini düşünmekteyiz. Toplumumuzda AS hastalarında HLA-B27 frekansını daha net ortaya koyabilmek için kesin tanı almış daha geniş hasta popülasyonunda çalışmalara ihtiyaç vardır.
Outcomes with Additional Manual Lymphatic Drainage to Rehabilitation Protocol in Primary Total Knee Arthroplasty Patients: Preliminary Clinical Results
Authors: CİHAN Emine , ÜN YILDIRIM Necmiye , BİLGE Onur , BAKAR Yeşim , DORAL Mahmut
Published: January 2022

Objective: This study was carried out to evaluate the clinical outcomes such as pain, kinesiophobia and quality of life of additional manual lymph drainage (MLD) technique in the after total knee arthroplasty (TKA) surgery.Methods: Twenty-one TKA patients were randomly allocated to a control group (n:10) and MLD group (n:11). Both groups received routine postoperative rehabilitation. MLD group also received MLD in the first three days after surgery. Clinical assessment was undertaken on postoperative 3rd day and at 6th week. This included knee pain using Visual Analog Scale (VAS), kinesiophobia using Tampa Kinesiophobia Scale (TKS) and quality of life using Nottingham Health Profile (NHP).Results: VAS and TKS values of the MLD group on the 3rd day and at the 6th week were found to be significantly lower than the control group (p<0.05). The 6th week NHP values of the MLD group were found to be significantly lower than the control group (p<0.05). For all three values, within-group, and between-group according to processes the effect size of the MLD group is greater than the control group.Conclusion: The results of the present study demonstrated that addition of MLD application to the standard rehabilitation protocol of TKA positively affected the healing process and it also improved the quality of life by reducing postoperative kinesiophobia and pain level. Adding this special technique to the rehabilitation program in TKA surgeries will provide patient satisfaction and contribute positively to the improvement in clinical outcomes.
COVID-19 Awareness of the Optician Students
Authors: USTA Gülşah , BAŞER KOLCU Mukadder İnci , KARACA Umut
Published: January 2022

Objective: The aim of this study was to determine optician students’ level of COVID-19 awareness and their attitude toward the use of personal protective equipment. Material – Method: A cross-sectional study was conducted with a research population that consisted of Isparta University of Applied Sciences, Technical Sciences Vocational School, Department of Opticians students, who voluntarily participated in the study (n = 76). The questionnaire contained three parts (35 questions): demographic data (5 questions), awareness of COVID-19 (15 questions), and the transmission and prevention of COVID-19 infections at the workplace (15 questions). Results: A total of 76 students, 67.1% of whom were women, were included in the survey. In the COVID-19 awareness part of the survey, 82.9% of the respondents reported that they knew about COVID-19, and 19.7% of them defined that this infection did not cause conjunctivitis. Regarding frames, 44.7% of the respondents stated that they would avoid frame fitting during the pandemic, and 96.1% plan to disinfect them after they have been tried on by customers. Conclusion: The level of knowledge and awareness about this disease should not be compromised. The scope of our study revealed both that there is no training on this subject and the need for that training.
A PROMETHEE II-BELIEFapproach for multi-criteria decision-making problems with incomplete information
Authors:   OLID Research Laboratory, University of Sfax, Higher Institute of Industrial Management of Sfax, Road of Tunis km 10.5, Technopole of Sfax  BP 1164, Sfax 3021, Tunisia, Frikha Hela Moalla , Frikha Ahmed ,   OLID Research Laboratory, University of Sfax, Higher Institute of Industrial Management of Sfax, Road of Tunis km 10.5, Technopole of Sfax  BP 1164, Sfax 3021, Tunisia
Published: January 2022

Multi-criteria decision aid methods consider decision problems in which many alternatives are evaluated on several criteria. These methods are used to deal with perfect information. However, in practice, it is obvious that this information requirement is too strict. In fact, the imperfect data provided by more or less reliable decision makers usually affect decision results, since any decision is closely linked to the quality and availability of information. In this paper, a PROMETHEE II-BELIEF approach is proposed to help multi-criteria decisions based on incomplete information. This approach solves problems with incomplete decision matrix and unknown weights within PROMETHEE II method. On the basis of belief function theory, our approach first determines the distributions of belief masses based on PROMETHEE II’s net flows, and then calculates weights. Subsequently, it aggregates the distribution masses associated with each criterion using Murphy’s modified combination rule in order to infer a global belief structure. The final alternative ranking is obtained via pignistic probability transformation. A case study of a real-world application concerning the location of a treatment center of waste from healthcare activities with infectious risk in the center of Tunisia is studied to illustrate the detailed process of the PROMETHEE II-BELIEF approach. Keywords: multiple criteria aid, incomplete information, PROMETHEE II method, belief function theory.
CORRELATION BETWEEN URIC ACID LEVEL WITH BODY MASS INDEX AND HEMATOLOGY PARAMETERS AMONG HYPERURICEMIA PATIENTS
Authors: Fitriani Ulfa , Zulkarnain Zuraida , Wijayanti Enggar
Published: January 2022

Hyperuricemia has became the public health issue worldwide. Hematology parameters abnormality is considered to be one of the factors relating the disease such as hyperuricemia. Current study suggest that body mass index (BMI) related to uric acid (UA) levels. The aim of the study was to examine the association between uric acid levels and hematological parameters and BMI among hyperuricemia patients. This was cross sectional study with 50 hyperuricemia patients in Hortus Medicus clinic. Results demonstrate that of the participants, 54% were women but the mean of UA levels was higher in the men (8,41 + 0,80 mg/dL) than in women (7,38 + 0,97 mg/dL). In BMI classified, the mean BMI for men was normoweight, and the women was overweight. The mean of hematology parameters in both of sex were normal range. No significant association were testified between uric acid levels and hemoglobin, hematocrit, erythrocyte, trombocyt, leukocyte and BMI. This study indicate that uric acid has no apparent association with hematology parameters and BMI
Evaluation of a Musculoskeletal Ultrasound Workshop in the Family Medicine Clerkship
Authors: Ferderber Megan L. , Vann Kaitlyn , Tzaras Athanasios , Hadadi Noam , Gilbird Rebecca M.
Published: January 2022

Background and Objectives: The family medicine (FM) clerkship is appropriate for incorporating musculoskeletal ultrasound (MSKUS) education, as many outpatient visits in primary care occur for musculoskeletal (MSK) concerns. Despite rising popularity of point-of-care imaging in primary care, ultrasound (US) training in medical education is limited due to lack of resources and time. The purpose of this study is to evaluate the effects of an MSKUS workshop in the FM clerkship through student self-evaluations.
Methods: Seventy-five medical students enrolled in the FM clerkship during the 2019-2020 academic year participated in hands-on MSKUS workshops staffed by faculty, residents, and a fellow. Workshops coincided with FM residency didactic teaching, allowing for protected time to host US training. Of workshop participants, 98.6% completed both pre- and postworkshop evaluations assessing confidence and acceptability of the workshop (rated on a 0-10 Likert scale, where higher scores represent more confidence or greater benefit, respectively).
Results: Students noted increased confidence with use of ultrasound, recognition of MSK structures, and performance of landmark-guided procedures (preworkshop 2.6±1.6; postworkshop 7.4±1.1). Students endorsed high levels of agreement in the benefit of the workshop to their education (9.4±1.3) and MSK understanding (9.4±1.2).
Conclusions: This study demonstrates the benefit of an MSKUS workshop as part of the FM clerkship and addresses previously identified challenges to providing US education. Results suggest a short-term benefit from an MSKUS workshop in confidence in MSKUS knowledge and satisfaction with the curriculum.
Roles of Academic Writers in a Department: Benefits, Structures, and Funding
Authors: Weidner Amanda , Elwood Samantha , Thacker Erin E. , Furst Wendy , Partington Leigh , Asif Irfan M. , Zazove Philip , Johnson Theodore M. , Okuyemi Kola , Gilchrist Valerie
Published: January 2022

Background and Objectives: Despite the prevalence of published opinions about the use of professional academic writers to help disseminate the results of clinical research, particularly opinions about the use of ghost writers, very little information has been published on the possible roles for professional writers within academic medical departments or the mechanisms by which these departments can hire and compensate such writers. To begin addressing this lack of information, the Association of Departments of Family Medicine hosted an online discussion and a subsequent webinar in which we obtained input from three departments of family medicine in the United States regarding their use of academic writers. This discussion revealed three basic models by which academic writers have benefitted these departments: (1) grant writing support, (2) research and academic support for clinical faculty, and (3) departmental communication support. Drawing on specific examples from these institutions, the purpose of this paper is to describe the key support activities, advantages, disadvantages, and funding opportunities for each model for other departments to consider and adapt.
Trombocitopenia inmune primaria: reporte de casos no respondedores al tratamiento
Authors: F B Cabrera , I Gutiérrez Magaldi , P Lucero , V Bressan , M L Salvano , F Gazzoni
Published: January 2022

La trombocitopenia inmune primaria (PTI) es una patología rara caracterizada por trombocitopenia aisladade origen autoinmune, con un recuento <100 x109 plaquetas/l no asociado a una patología reconocible, quecursa con un aumento del riesgo de hemorragia. No existe ninguna prueba confirmatoria definitiva paraestablecer su diagnóstico, que se realiza fundamentalmente por exclusión. Existe un pequeño porcentaje depacientes que no responden al tratamiento convencional. Se denomina PTI refractaria a la trombocitopeniasevera que persiste luego de realizada la esplenectomía, mientras que los pacientes que cumplen criteriosde PTI severa pero que no han sido esplenectomizados se consideran “no respondedores” a los fármacosutilizados hasta ese momento. Se presentan tres casos clínicos de PTI severa, persistente y crónica, norespondedores al tratamiento, con el objetivo de señalar la importancia de una concienzuda pesquisadiagnóstica y el desarrollo de una eficaz combinación de tratamientos para el manejo de esta complejapatología.
A bacterium-like particle vaccine displaying Zika virus prM-E induces systemic immune responses in mice
Authors: Jin Hongli , Bai Yujie , Wang Jianzhong , Jiao Cui , Liu Di , Zhang Mengyao , Li Entao , Huang Pei , Gong Zhiyuan , Song Yumeng , Xu Shengnan , Feng Na , Zhao Yongkun , Wang Tiecheng , Li Na , Gao Yuwei , Yang Songtao , Zhang Haili , Li Yuanyuan , Xia Xianzhu , Wang Hualei
Published: January 2022

The emergence of Zika virus (ZIKV) infection, which is unexpectedly
associated with congenital defects, has prompted the development of safe
and effective vaccines. The gram-positive enhancer matrix-protein anchor
(GEM-PA) display system has emerged as a versatile and highly effective
platform for delivering target proteins for vaccines. In this article,
we developed a bacterium-like particle vaccine ZI-△-PA-GEM based on the
GEM-PA system. The fusion protein ZI-△-PA, which contains the prM-E-△
protein of ZIKV (with a stem-transmembrane region deletion) and the
protein anchor PA3, was expressed. The fusion protein was successfully
displayed on the GEM surface, forming ZI-△-PA-GEM. Moreover, when BALB/c
mice were immunized intramuscularly with ZI-△-PA-GEM combined with 201
VG and poly(I:C) adjuvants, durable ZIKV-specific IgG and protective
neutralizing antibody responses were induced. Potent B cell/DC
activation was also be stimulated early after immunization. Remarkably,
splenocyte proliferation, the secretion of multiple cytokines, T/B cell
activation and central memory T cell responses were elicited. These data
indicate that ZI-△-PA-GEM is a promising bacterium-like particle vaccine
candidate for ZIKV.
LEFT FREE WALL-SIDED MAHAIM TYPE FIBER AND AV NODAL REENTRY TACHYCARDIA -- UNUSUAL BUT NOT IMPOSSIBLE COMBINATION
Authors: Stoyanov Мilko , Shalganov Tchavdar
Published: January 2022

A 52-year-old patient with previous catheter ablation of AV nodal
reentrant tachycardia (AVNRT) had a redo procedure for reported
recurrence. During the study AVNRT was not inducible, but a previously
unrecognized left-sided Mahaim type accessory pathway was diagnosed and
ablated successfully.
Computational Envision of Structural, Electronic, Mechanical and Thermoelectric Properties of PdXSn (X=Zr, Hf) half Heusler compounds
Authors: Rani Bindu , Wani Aadil , Sharopov Utkir , Kaur Kulwinder , Dhiman Shobhna
Published: January 2022

Half heusler compounds have gained attention due to their excellent
properties and good thermal stability. In this paper, using first
principle calculation and Boltzmann transport equation, we have
investigated structural, electronic, mechanical and thermoelectric
properties of PdXSn (X=Zr,Hf) half Heusler materials. These materials
are indirect band gap semiconductors with band gap of 0.52 (0.44) for
PdZrSn (PdHfSn). Calculations of elastic and phonon characteristics show
that both materials are mechanically and dynamically stable. At 300K the
magnitude of lattice thermal conductivity observed for PdZrSn is 15.16
W/mK and 9.53 W/mK for PdHfSn. The highest ZT value for PdZrSn and
PdHfSn is 0.32 and 0.4 respectively.
Reksc, M. (2019). Wyobrazenia zbiorowe spoleczenstw bylej Jugoslawii w XXI wieku. Perspektywa politologiczna, Lodz: Wydawnictwo Uniwersytetu Lódzkiego
Authors: Baraniak Karolina
Published: January 2022

nema
From “Porta Fossiensis” to Fossae exploring the roman road system in the Glac Study Area east of Sirmium
Authors: Dimitrijevic Milijan , Whitehouse John
Published: January 2022

As part of a comprehensive archaeological survey of the area around the site
of Glac, near ancient Sirmium, a detailed examination has been undertaken of
the location of the via militaris from Sirmium to Bassianae in light of
previous studies and new field surveys. In locating the road, the questions
of the findspot of two Roman milestones, the location of the eastern gate of
the city of Sirmium, the nature of road way stations including mutationes,
and the likely location of the way station at Fossae mentioned in the
Bordeaux Itinerary and Ravenna Cosmology have been considered. The
implications of the road construction on the patterns of rural settlement
and economy in the Glac Study Area are highlighted.
Expression of Kv4.2 and Kv4.3 potassium channels in human umbilical veins from normal, diabetic and hypertensive pregnancies
Authors: Djokic Vladimir , Gostimirovic Milos , Rajkovic Jovana , Rakocevic Jelena , Labudovic-Borovic Milica , Jankovic Svetlana , Stanisic Jelena , Kostic Milan , Djuric Milos , Gojkovic-Bukarica Ljiljana
Published: January 2022

Background/Aim. A substantial line of evidence indicates that Kv4.2 and Kv4.3 channels are the major components of rapid transient-outward potassium currents (A-type cur-rents). It is speculated that those currents may be involved in the maintenance of the membrane potential, as well as in the regulation of propagation and frequency of action potentials. However, very little is known about the presence and function of A-type currents in human vascular smooth muscles such as the human umbilical vein (HUV). Bearing in mind its crucial role in the proper fetal oxygenation, the aim of the study was to determine whether Kv4.2 and Kv4.3 potassium channels are present in HUV smooth muscle and to investigate potential alterations of their expression during maternal pathological conditions such as gestational diabetes mellitus (GDM) and pregnancy-induced hypertension (PIH). Methods. Healthy, diabetic, and hypertensive pregnancies were subjects of this investigation. Each group consisted of 6 HUV samples obtained from 6 normal pregnancies, 6 pregnancies with GDM, and 6 with PIH. After pharmacology analysis, immunohistochemistry (IH) and Western blot were performed. Results. IH revealed similar expression patterns of both, Kv4.2 and Kv4.3 subunits in HUV smooth muscle in all groups of patients. Results obtained by Western blot were in agreement with IH staining. The expression of Kv4.2 and Kv4.3 subunits were not significantly different between the groups. Conclusion. Collective-ly, this is the first study that demonstrated the presence of Kv4.2 and Kv4.3 potassium channels in the HUV smooth muscle and their preservation during GDM and PIH pregnancies. These channels are most likely major components of rapid A-type currents that may be relevant for maternal-fetus blood flow and hence fetal development. In addition, they may represent sensors for detecting hemodynamic and/or metabolic changes in the local environment.
Combined orthodontic and surgical open bite correction:
Authors: Arnett G. William , Trevisiol Lorenzo , Grendene Elisabetta , McLaughlin Richard P. , D'Agostino Antonio
Published: January 2022

Objectives:

To examine the stability of combined surgical and orthodontic bite correction with emphasis on open-bite closure. All study patients were treated with strict and consistent orthodontic and surgical protocols.

Materials and Methods:

Study inclusion required all patients to have anterior open bites, maxillary accentuated curve of Spee, 36-month minimum follow-up, and no temporomandibular joint pathology. Thirty patients met the inclusion/exclusion criteria. Importantly, segmental upper arch orthodontic preparation (performed by EG) was used. Surgery consisted of a multisegment Le Fort I (MSLFI) combined with a bilateral sagittal osteotomies (BSSO). Surgery was performed (by ADA and LT) at the Department of Dentistry and Maxillofacial Surgery of the University of Verona, Italy.

Results:

The long-term open bite and overjet relapse were not statistically significant. The mean transverse relapse of the upper and lower molars was statistically significant. Of great importance, the upper and lower arch widths narrowed together, maintaining intercuspation of the posterior dentition which prevented anterior open bites from developing.

Conclusions:

This study revealed stability of three-dimensional occlusal correction including anterior open bite. Stable open bite closure was achieved by using rigid protocols for orthodontic preparation, surgical techniques, surgical follow-up, and orthodontic finishing.
Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study
Authors: Martin Susan , Sorokin Elena P. , Thomas E. Louise , Sattar Naveed , Cule Madeleine , Bell Jimmy D. , Yaghootkar Hanieh
Published: January 2022

OBJECTIVE

Fat content and volume of liver and pancreas are associated with risk of diabetes in observational studies; whether these associations are causal is unknown. We conducted a Mendelian randomization (MR) study to examine causality of such associations.

RESEARCH DESIGN AND METHODS

We used genetic variants associated (P < 5 × 10−8) with the exposures (liver and pancreas volume and fat content) using MRI scans of UK Biobank participants (n = 32,859). We obtained summary-level data for risk of type 1 (9,358 cases) and type 2 (55,005 cases) diabetes from the largest available genome-wide association studies. We performed inverse-variance weighted MR as main analysis and several sensitivity analyses to assess pleiotropy and to exclude variants with potential pleiotropic effects.

RESULTS

Observationally, liver fat and volume were associated with type 2 diabetes (odds ratio per 1 SD higher exposure 2.16 [2.02, 2.31] and 2.11 [1.96, 2.27], respectively). Pancreatic fat was associated with type 2 diabetes (1.42 [1.34, 1.51]) but not type 1 diabetes, and pancreas volume was negatively associated with type 1 diabetes (0.42 [0.36, 0.48]) and type 2 diabetes (0.73 [0.68, 0.78]). MR analysis provided evidence only for a causal role of liver fat and pancreas volume in risk of type 2 diabetes (1.27 [1.08, 1.49] or 27% increased risk and 0.76 [0.62, 0.94] or 24% decreased risk per 1SD, respectively) and no causal associations with type 1 diabetes.

CONCLUSIONS

Our findings assist in understanding the causal role of ectopic fat in the liver and pancreas and of organ volume in the pathophysiology of type 1 and type 2 diabetes.
The Noble and Often Nobel Role Played by Insulin-Focused Research in Modern Medicine
Authors: Harrison Victor S. , Khan Mahfuzul H. , Chamberlain Christine E. , Harlan David M.
Published: January 2022

Since diabetes was first described over 3,000 years ago, clinicians and scientists alike have sought ever improving treatments en route to a cure. As we approach the 100th anniversary of insulin’s first therapeutic use, this article will recount the glorious history associated with research surrounding insulin’s isolation, purification, cloning, and subsequent modification. The discovery path we will relate tells the story of many relentless and passionate investigators pursuing ground-breaking research. The fruits of their labor include several Nobel Prizes, new technology, and, more importantly, ever improving treatments for one of humankind’s greatest medical scourges.
STEAM Oriented Science Learning Management During The COVID-19 Pandemic
Authors: Priyantini Mimin Vera Dwi , Sumardjoko Bambang , Widyasari Choiriyah , Hidayati Yulia Maftuhah
Published: January 2022

This research is motivated by the importance of experimentation in science learning which cannot be done directly in online learning during the pandemic. The application of STEAM is one solution to problems that arise in the management of science learning in elementary schools during the pandemic. The subjects of this study were 20 grade 6 students in an elementary school in Surakarta. The method used in this study was descriptive qualitative with a case study design. The recruited informants consisted of students and their parents. The techniques used in this research are interviews, observation and documentation. Data analysis using data collection techniques, data reduction, presentation of power and drawing conclusions. The data validity technique is technique triangulation and source triangulation. The results of this study indicate that (1) the application of online learning changes the way students learn (2) In online learning experiments cannot be done directly (3) During the pandemic, teachers are required to innovate in the teaching and learning process (4) The STEAM approach can provide a meaningful experience for students (5) STEAM can encourage student development for the better. The implications of this research are: First, more and more teachers are implementing the STEAM approach in the teaching and learning process as an alternative so that students can learn optimally. Both parents are willing to take the time to observe and assist their daughter's online learning process. This study describes the application of the STEAM approach in online learning during a pandemic
O FENÔMENO DA REPETIÇÃO EM UMA ENTREVISTA ORAL TELEVISIVA DA ESFERA JORNALÍSTICA
Authors: Rocha Max Silva da , Costa Daniela Carla Silva , Cavalcante Sandra Araújo Lima
Published: January 2022

Este estudo, inserido na Análise da Conversação, versa sobre o fenômeno da repetição e como ele atua no texto conversacional, mais especificamente, na tessitura do gênero entrevista oral televisiva. O objetivo deste trabalho é realizar uma análise sobre o modo como a repetição contribui com a textualidade no citado gênero e como ela se apresenta durante as trocas comunicativas entre entrevistador e entrevistado. A partir das análises qualitativas, percebemos que a repetição foi uma categoria decisiva para a continuidade da conversação por meio do gênero entrevista. Por meio dessa categoria, os interlocutores conversaram e suscitaram diferentes efeitos de sentido, os quais reverberaram nuances que se estabelecem no campo da polêmica. Provavelmente, sem o uso da repetição, essas trocas comunicativas não teriam os mesmos efeitos, razão por que assumimos a importância desse dispositivo textual e discursivo para o texto conversacional, neste caso, para a entrevista oral televisiva da esfera jornalística.
A ORGANIZAÇÃO LINGUÍSTICO-DISCURSIVA DOS ARTIGOS DE OPINIÃO COMO REDAÇÃO DE VESTIBULAR QUE ALCANÇAM BOAS NOTAS
Authors: Striquer Marilúcia dos Santos Domingos , Ribeiro Leandro
Published: January 2022

Este trabalho tem como objetivo compreender como as redações que alcançaram a maior nota em um concurso de vestibular organizaram a escrita do artigo de opinião solicitado como redação. Foram analisados quatro exemplares produzidos em um vestibular de 2020, tendo como categoria as definições e os elementos regulares característicos do gênero textual. Os resultados demonstraram que as maiores e mais frequentes dificuldades presentes nas redações investigadas estão relacionadas à articulação de recursos linguístico-gramaticais, o que afetou a coerência semântica dos textos, e o emprego de estratégias que se relacionam à redação do ENEM, não ao artigo de opinião, acarretando penalizações que impossibilitaram os textos de alcançarem a nota máxima.
PELATIHAN PENGGUNAAN SOFTWARE PENILAIAN KESEHATAN HUTAN DI KTH LESTARI INDAH LABUHAN MARINGGAI LAMPUNG TIMUR
Authors: Safe'i Rahmat , Aristoteles  , Mulkhan Unang , Pratama Rizky , Ajijah Lis Nur , Syahiib A. Nizam , Selvira  , Nabila Annisa Putri , Damayanti Risna
Published: January 2022

Pentingnya pengetahuan perihal kesehatan hutan yaitu diperlukan untuk mengetahui gangguan yang terjadi, sehingga perlu dilakukan pemantauan kesehatan hutan secara berkala. Pemantauan kesehatan hutan adalah salah satu cara untuk menjamin kelestarian hutan salah satunya hutan mangrove. Pengabdian ini bertujuan untuk meningkatkan pemahaman anggota Kelompok Tani Hutan (KTH) Lestari Indah mengenai penggunaan Sistem Informasi Penilaian Kesehatan Hutan (SIPUT). Sasaran pengabdian ini adalah anggota KTH Lestari Indah. Tingkat pemahaman peserta perlu diketahui sehingga dilakukannya evaluasi melalui dua tahap yaitu evaluasi awal (pre-test) dan evaluasi akhir (post-test) dengan cara pemberian kuesioner. Hasil perhitungan menunjukkan bahwa terjadi peningkatan pemahaman peserta tentang penggunaan software penilaian kesehatan hutan yaitu dengan rerata nilai pre-test dan post-test masing-masing sebesar 61,125% dan 80,125%. Persentase kenaikan pengetahuan peserta dari hasil pre-test dan post-test adalah 19%. Oleh karena itu, penggunaan software SIPUT merupakan media yang tepat untuk mempermudah penilaian kondisi kesehatan hutan mangrove.
Development of interactive learning media of automotive lighter vehicle maintenance machine in SMK N 1 Padang
Authors: Putra Meiyaldi Eka , Maksum Hasan
Published: January 2022

Learning Media for Automotive Vehicle Engine Maintenance still uses a simple medium consisting of whiteboards and worksheets, which encourages less effective learning to develop more interactive media and supports students to more easily understand the basic concepts of Automotive Light Vehicle Engine Maintenance lessons. This development research aims to develop interactive learning media that is packaged interactively in the subject of Automotive Light Vehicle Engine Maintenance. This research method is R&D with One Group Pretest-Posttest design. The procedure of this research was carried out in the stages of defining, designing and developing. The subjects of this study were 28 students from SMK N 1 Padang in class XI OTO A. The data collected in this study consisted of primary data obtained directly from respondents in the format obtained. This research instrument consisted of a questionnaire of validity, practicality and effectiveness. The research data collected was analyzed using t test analysis. The results obtained from this research and development are as follows: (1) the validity of interactive learning media is stated to be very valid from didactic, construction and technical requirements with an average score of 94.16%. (2) The practicality of interactive learning media is stated to be very practical based on teacher responses with an average score of 95%, based on student responses also expressed very practical with an average score of 91.17%. (3) The effectiveness of interactive learning media can be seen from student learning outcomes before and after using the media. This is evidenced by the significant differences in the use of interactive learning media obtained from student learning outcomes. Improved student learning outcomes are changed by the students' completeness value of KKM with an average value of 86.61, which means students are complete in learning.