bluuebunny/crossref_metadata_2025 huggingface dataset:
Examining the Relationships Between Indoor Environmental Quality Parameters Pertaining to Light, Noise, Temperature, and Humidity and the Behavioral and Psychological Symptoms of People Living With Dementia: Scoping Review (Preprint)
Authors: Au-Yeung Wan-Tai M , Miller Lyndsey , Wu Chao-Yi , Beattie Zachary , Nunnerley Michael , Hanna Remonda , Gothard Sarah , Wild Katherine , Kaye Jeffrey
Published: August 2024

BACKGROUND

A common challenge for individuals caring for people with Alzheimer disease and related dementias is managing the behavioral and psychological symptoms of dementia (BPSD). Effective management of BPSD will increase the quality of life of people living with dementia, lessen caregivers’ burden, and lower health care cost.

OBJECTIVE

In this review, we seek to (1) examine how indoor environmental quality parameters pertaining to light, noise, temperature, and humidity are associated with BPSD and how controlling these parameters can help manage these symptoms and (2) identify the current state of knowledge in this area, current gaps in the research, and potential future directions.

METHODS

Searches were conducted in the CINAHL, Embase, MEDLINE, and PsycINFO databases for papers published from January 2007 to February 2024. We searched for studies examining the relationship between indoor environmental quality parameters pertaining to light, noise, temperature, and humidity and BPSD.

RESULTS

A total of 3123 papers were identified in the original search in October 2020. After an additional 2 searches and screening, 38 (0.69%) of the 5476 papers were included. Among the included papers, light was the most studied environmental factor (34/38, 89%), while there were fewer studies (from 5/38, 13% to 11/38, 29%) examining the relationships between other environmental factors and BPSD. Of the 38 studies, 8 (21%) examined multiple indoor environmental quality parameters. Subjective data were the only source of environmental assessments in 6 (16%) of the 38 studies. The findings regarding the relationship between agitation and light therapy are conflicted, while the studies that examined the relationship between BPSD and temperature or humidity are all observational. The results suggest that when the environmental factors are deemed overstimulating or understimulating for an individual with dementia, the behavioral symptoms tend to be exacerbated.

CONCLUSIONS

The findings of this scoping review may inform the design of long-term care units and older adult housing to support aging in place. More research is still needed to better understand the relationship between indoor environmental quality parameters and BPSD, and there is a need for more objective measurements of both the indoor environmental quality parameters and behavioral symptoms. One future direction is to incorporate objective sensing and advanced computational methods in real-time assessments to initiate just-in-time environmental interventions. Better management of BPSD will benefit patients, caregivers, and the health care system.
Social support and self-compassion: Their influence on work-family conflict among mothers employed as nurses
Authors: Putri Desthia Tasya Mahardhika , Hijrianti Udi Rosida , Syafitri Diany Ufieta
Published: August 2024

Nurses bear the responsibility of providing care to patients amidst demanding work schedules. For a mother working as a nurse, balancing roles in both profession and family becomes a priority; failure to achieve this balance may lead to conflict. This study investigates the predictive ability of social support and self-compassion on work-family conflict among nurse mothers. The study involved 143 nurse mothers recruited through accidental sampling methods. Instruments employed included the Multidimensional Scale of Perceived Social Support (MSPSS), self-compassion scale, and work-family conflict scale. Multiple linear regression analysis revealed that social support and self-compassion collectively predict work-family conflict among nurse mothers (R²= 0.130, F = 10.487, p= 0.00). The ability of social support and self-compassion to predict work-family conflict was 13%, with the remaining variance attributable to unexamined variables in this study. The implications of this study suggest that managing work-family conflict necessitates social support from family, supervisors, colleagues, and friends. Furthermore, enhancing self-compassion through self-kindness, acknowledging common humanity, and fostering mindfulness while reducing self-judgment, isolation, and over-identification could prove advantageous.
Identification of psychometric properties of acculturative stress scale for international students
Authors: Karyanta Nugraha Arif , Suryanto Suryanto , Matulessy Andik
Published: August 2024

Ensuring reliable measurement instruments is crucial for psychologists and practitioners. The Acculturative Stress Scale for International Students (ASSIS) is a widely used tool for assessing acculturative stress. An analysis of data from 100 international students in Indonesia demonstrated that the ASSIS met reliability standards, with AVE values between 0.50 and 0.63 and CR values between 0.73 and 0.91. The ASSIS also satisfied the criteria for content and construct validity. Additionally, the factorial validity of the ASSIS-1 CFA model met 5 out of 6 criteria, including RMSEA < 0.08, SRMR < 0.10, and NFI, CFI, and GFI values > 0.90, while the ASSIS-2 CFA model fulfilled all 6 criteria. Consequently, it can be concluded that the ASSIS is a valid and reliable tool for international students in the Indonesian cultural context.
A Comparison of Regions' Educational Gap and Depopulated Areas: Predicting Trends in Regional Population Characteristics through Topic Modeling of News from 2004 to 2023 and Time Series Analysis
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Hyoeun , Lee Eunhye , Choi Naya
Published: August 2024

Objectives The purposes of this study were to analyze the trends in regional education disparities as depicted in news articles over a 20-year period and predict regional population characteristics, comparing them with depopulated areas.
Methods A total of 14,263 news articled on regional education disparities from 2004 to 2023 were analyzed to discern reporting trends. Utilizing topic modeling, key terms and major topics were extracted from the articles. Time series analysis was employed to forecast population chracteristic for the top 15 depopulated regions.
Results First, the number of news articles on region educaional gap significantly increased in 2006 and 2010, followed by a decreasing trend from 2011 to 2019, but surged again from 2020 onwards. Relative lack of interest was observed in early childhood and elementary education. Second, 11 topics, along with 50 keywords identified in the articles, were categorized into two overarching themes; the realities of regional education disparities and strategies for addressing them. Third, populations in the top 15 depopulated regions highlighted in the articles are predicted to decline sharply over the next five years.
Conclusions This study structurally examined a long-term societal issue of regional education disparities over 20 years, providing foundational data for policy-making and practical implementation in the education sector by viewing education disparities from the perspective of population decline.
The Study on Korean language education practices in Vietnam: Focusing on the Practice of Korean Language Education in the Department of Korean Language at Hanoi Thang Long University
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Park Eun Jin , TRAN THI BICH PHUONG TRAN THI BICH PHUONG
Published: August 2024

Objectives The purpose of this study is to examine the practice aspects of Korean language education in Vietnam through cooperation and communication between domestic and foreign researchers. We sought to examine the aspects of Korean language education being conducted at Thang Long University, the first private university in Vietnam, and identify its implications for Korean language education. Rather than simply describing the aspects of Korean language education abroad from the perspective of others, researchers from both countries examine this together from a collaborative perspective to ultimately seek implications that can contribute to substantially improving the Korean language education scene at home and abroad.
Methods Rather than simply describing the aspects of Korean language education abroad from the perspective of others, researchers from the two countries examine this together from a collaborative perspective to ultimately seek implications that can contribute to substantially improving the Korean language education field at home and abroad.
Results As a result, the characteristics of the Korean language curriculum are that it mainly deals with the cultural capital that Korean language learners already have, and that it provides interpretation and translation classes as the highest level classes to foster global talent who can utilize both the learner's native language and the target language. The point is that it is aimed at . As a result of examining the actual aspects of textbooks and teaching and learning, focusing on , the highest level class held at Thang Long University, it was found that this is being achieved through a cooperative learning method that gradually completes translation through communication. We were able to discover, and through this, we were able to understand the aspect of respecting Korean language learners' voluntary learning will and capabilities even in the actual class.
Conclusions This aspect of Korean language education practice at Thang Long University in Vietnam provides various topics for discussion regarding the goal setting of Korean language education and action plans in teaching and learning, and suggests implications for the direction of realization of learner-centeredness in Korean language education.
A Comparative Study on the Teacher Qualification System in Korea and China
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, XIE HUI XIE HUI , TAI XUEMEI TAI XUEMEI , Kim Byungchan
Published: August 2024

Objectives This study aims to provide meaningful content that can be used as a reference for the development of educational specialization in the development of high school teachers' qualifications by presenting differences in structural, compositional, and technical dimensions and future development directions through a comparative study of the teacher qualification system between Korea and China for educational development.
Methods To this end, literature data on the teacher qualification system in Korea and China were collected as much as possible and conducted as a comparative research method. Through the analysis framework of multidimensional theory such as Cooper, the process of historical transformation with implementation organizations or institutions of the teacher qualification system in both countries, the benefits and acquisition process of the teacher qualification system, and the actual use in the educational field were analyzed.
Results As a result of the study, Korea has maintained the quality of education by relying on teacher training institutions such as the College of Education, the College of Education, the Graduate School of Education, and the completion of teaching courses, and has reformed the teacher qualification system earlier than in China. If Korea passes the appointment test, it becomes an educational official, but in China, the appointment test and the civil service test are completely separated. When it comes to cultivating teachers, Korea places importance on the ability and level of knowledge of teachers, and China places more importance on cultivating teachers' professional and ideological character.
Conclusions For educational development, it is necessary to raise interest in the training of learners to become teachers, introduce a teacher training curriculum suitable for national standards or regional units, and strengthen the expertise of teacher training institutions.
A study on the experiences of pre-service early childhood teachers who participated in major classes applying gamification
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Woo Young , Jung Hye Young
Published: August 2024

Objectives The purpose of this study was to analyze the meaning of experiences of pre-service early childhood teachers who participated in a major course incorporating gamification.
Methods Gamification was applied for one semester in the course “Early Childhood Education Curriculum,” a major subject for sophomores in the Department of Early Childhood Education at C College in Jeollanam-do. After each class, reflective journals written by eight pre-service early childhood teachers, who were the participants of the study, were analyzed. Additionally, individual interviews between the researcher and the participants were conducted to verify the validity of the journal contents, and these were analyzed to derive the meanings of their experiences.
Results The experience of the study participants was largely classified into two topics: ‘participating as a learner’ and ‘experiencing as a teacher’. In ‘participating as a learner’, the participants experienced ‘positive emotions’, ‘self-directed learning’, and ‘reestablishing relationships’. In ‘experiencing as a teacher’, they experienced ‘autonomy’, ‘understanding teaching methods’, and ‘deep understanding of play’.
Conclusions Participants in the study were able to understand various teaching methods and recognize the meaning and value of play as early childhood teachers through classes applying gamification.
Comparision of 11C-methionine and 11C-choline pet/ct for parathyroid visualization: a prospective study
Authors: Pogosian K. А. , Karonova T. L. , Ryzhkova D. V. , Yanevskaya L. G. , Boriskova M. E. , Zuykevich D. V. , Yudina O. V. , Tsoy U. A. , Grineva E. N.
Published: August 2024

INTRODUCTION: Primary hyperparathyroidism (PHPT) is a common endocrine disorder. Minimal invasive parathyroidectomy (PTX) is favorable surgical approach in PHPT treatment. Its success is highly dependent on accurate preoperative localization of all causative parathyroid adenomas. Despite the fact that wide range of visualization methods are applied in PHPT diagnostics, PHPT persistence occurs. Therefore, the search for additional visualizing tools of parathyroid adenomas remains relevant. Recently, positron emission tomography/computed tomography (PET/CT) has been used in order to improve PHPT diagnostics. OBJECTIVE: To evaluate the diagnostic effectiveness of PET/CT with 11C-methionine and 11C-choline in patients with PHPT based on the intensity of both tracers uptake in parathyroid adenomas. MATERIALS AND METHODS: The data of 26 patients diagnosed with PHPT was analyzed. PET/CT with 11C-choline was performed in 14 patients, with 11C-methionine — in 10 patients, with two radiopharmaceuticals — in two patients. All patients underwent PTX. Histological examination’s results were compared with the results of PET/CT. Using the software, the standardized uptake value of radiopharmaceuticals in histologically verified parathyroid adenomas/hyperplasias and in the trapezius muscle was obtained, then tumor-to-background ratios (TBR) of 11C-methionine and 11C-choline were calculated.Statistics: Software STATISTICA 10 was used in statistical analysis.RESULTS: 11C-choline TBR median was of 2.3 (1.6; 3.2), median of 11C-methionine TBR showed slightly higher values — 2.5 (1.9; 3,6). However, no significant difference was found between the two radiopharmaceuticals’ uptake in parathyroid adenomas.DISCUSSION: The scientific impact of current study is determined by the diagnostic effectiveness comparison between PET/CT with 11C-methionine and 11C-choline, which is based on the accumulation intensity of both radiopharmaceuticals in parathyroid adenomas.CONCLUSION: The intensity of accumulation of 11C-methionine and 11C-choline by hyperfunctioning parathyroid tissue does not differ significantly. Thus both tracers might be successfully applied for topic diagnosis of parathyroid adenomas in patients with PHPT.
‘Paper Body’: Bureaucratic and Legal Dimensions of the Newborn Patient’s Trajectory Within Neonatal Care
Authors: Novkunskaya Anastasia , Minakov Artemiy , Klepikova Anna
Published: August 2024

This article explores the bureaucratic, legal and economic dimensions of the neonatal care. Drawing analytically on the neo-Weberian approach in the sociology of professions [Freidson 2001] and the anthropology of bureaucracy in medicine [Berg 1996; Berg & Bowker 1997], we propose to analyse the medical documents and the practices of its composition as both a constitutive element of medical practice and as organisational infrastructure that ensures the coordination of different professional groups and their interactions with patients. Specifically, we define this part of the work of doctors, nursing staff and health care managers in the context of neonatal resuscitation care as a process of creating and modifying a 'paper body' for their patients, i.e. all the document flow that accompanies the processes of treating and routing the patient. Empirically, the study relies on qualitative data collected within ‘the Birth of the Patient’ project: diaries of included observations of a neonatal intensive care physician, ethnographic observations by social researchers, focus groups with neonatal intensive care unit staff and interviews with medical professionals and healthcare managers. As a result of this data analysis, we find that the documentary history of the newborn patient is shaped by multiple negotiations between different medical professionals and representatives of different health care institutions. In some cases, the patient's 'paper body' turns out to be a major determinant of his or her future trajectory of (de)hospitalisation. We also find that the formation of such a documentary biography of a newborn patient does not directly correlate with his or her clinical condition, but reflects the complex system of distribution of material and non-material resources that constitute the newborn care service and in some cases goes beyond it.
AS ESTRATÉGIAS DE ENSINO NO CONTEXTO PÓS-PANDEMIA: UM OLHAR SOBRE O CICLO DE ALFABETIZAÇÃO
Authors: Costa Maria da Conceição , Alves Maria de Jesus , Leite Simone Cavalcanti Moreira
Published: August 2024

Diante do cenário vivenciado pelo mundo com a propagação da Covid-19 e os desafios que os professores vêm enfrentando em salas de aula brasileiras, desde a utilização do ensino remoto às demandas postas pelo contexto pós-pandemia, esse artigo aponta reflexões que objetivam discutir acerca da seguinte problemática: como as estratégias de ensino estão sendo repensadas no Ciclo de Alfabetização no contexto pós-pandemia, na perspectiva de um ensino articulado às demandas dos novos cenários epistemológicos e educacionais? A metodologia deste trabalho está fundamentada na pesquisa qualitativa, através de uma revisão bibliográfica que aciona autores que discutem a alfabetização, as mudanças epistemológicas no contexto pós-pandemia e seus impactos no ensino escolar, especificamente, nas estratégias de ensino aplicáveis ao Ciclo de Alfabetização, além de buscas em meio eletrônico, no Google Acadêmico, contemplando artigos que abordam a temática com foco no Ciclo de Alfabetização e amparo nas bases legais que normatizam a alfabetização no contexto brasileiro. As discussões abordadas apontam para a necessidade de reorganização de ações pedagógicas em função das incertezas postas no século XXI, de forma que as estratégias de ensino no Ciclo de Alfabetização estejam articuladas a uma formação de base inclusiva, democrática e pedagogicamente comprometida com a preparação de seres humanos críticos, que tenham acesso a relações cooperativas em seus processos de aprendizagem. Além de uma reorganização pedagógica, o contexto pós-pandemia exige investimentos de ordem técnica e financeira atrelados a políticas públicas voltadas ao planejamento de estratégias de recuperação da aprendizagem dos alunos, um trabalho que requer investimentos pedagógicos, sem desconsiderar as condições de trabalho docente e as desigualdades do entorno socioeconômico dos alunos e suas famílias.
LITERACIA MIDIÁTICA E COMBATE A FAKE NEWS: UM ESTUDO DE CASO COM O PÚBLICO DA TERCEIRA IDADE
Authors: Fernandes Carla Montuori Montuori , Oliveira Luiz Ademir de , Farnese Pedro Augusto , Augusto Luciana Janizello
Published: August 2024

Este estudo é o resultado de sistematizações teóricas e práticas sobre a extensão universitária voltada para pessoas idosas com foco na educação midiática, com vistas ao enfrentamento de contextos que envolvem a circulação de fake news. Um estudo de caso realizado a partir das ações do projeto Literamidia +50, uma parceria do IF Sudeste MG e Universidade Paulista, apontou caminhos analíticos que podem auxiliar na definição de estratégias de Literacia Midiática capazes de auxiliar na conscientização sobre os riscos que o ambiente virtual impõe aos cidadãos. A amostra compreendeu 17 integrantes (alunos), que frequentaram o curso durante o período de julho a dezembro de 2021 e aceitaram participar da pesquisa, assinando o Termo de Consentimento Livre e Esclarecido, após aprovação da pesquisa no Comitê de Ética em Pesquisa (CEP) da Universidade Paulista (UNIP). Os resultados revelaram que a literacia representa um caminho promissor no sentido de oportunizar ao idoso o acesso mais seguro e consciente da informação, que recebe e compartilha nas mídias digitais.
Os desafios do estado da Bahia para atender a volumosa demanda da educação de jovens e adultos
Authors: Borges Moacir Freitas , Cunha Maria Couto
Published: August 2024

Este trabalho teve como objetivo verificar a demanda potencial da Educação de Jovens e Adultos (EJA) na Bahia, iniciando pelo cenário nacional. Constitui um recorte de estudos em realização na linha de Política e Gestão da Educação do Programa de Pós-Graduação em Educação da Faculdade de Educação da Universidade Federal da Bahia. Em termos metodológicos, o estudo se valeu da pesquisa quantitativa utilizando dados estatísticos do Instituto Brasileiro de Geografia e Estatística (IBGE), para as informações demográficas, do Portal do Tribunal Superior Eleitoral (TSE) para os dados sobre grau de instrução da população de 16 anos e mais apta a votar em 2022, além dos dados do Ministério da Educação (MEC) e do Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira (INEP), sobre a oferta das matrículas desta modalidade de educação, além de análise qualitativa valendo-se da pesquisa bibliográfica. Como principais resultados, conclui-se pela existência de um grande contingente da população jovem e adulta sem ter o acesso garantido pela legislação a seu direito à educação, seja no ensino fundamental, seja no ensino médio, que somado com os analfabetos chegam à casa de mais de seis milhões de cidadãos baianos em 2022. Esta demanda, portanto, está a desafiar as políticas públicas no contexto brasileiro, diante da débil oferta de matrículas sob a responsabilidade dos sistemas de ensino, em especial, na Bahia, demanda esta que permanece acumulada nas últimas décadas e que deve se constituir em prioridade na elaboração dos futuros planos educacionais.
Política e gestão das creches da rede municipal de educação de Salvador-BA
Authors: Tigre Diana Martins
Published: August 2024

A educação é um direito de todos, devendo ser garantida em todos os níveis, sendo a educação infantil (EI), sua primeira etapa. Contudo, a EI parece ainda não ser prioridade em nosso país pois sua oferta só é obrigatória a partir dos 4 anos. Nesse cenário, as crianças de 0 a 3 anos carecem de vivenciar a educação nas creches, o que aponta a necessidade de compromisso para sua urgente implantação e expansão. Outro desafio que parece atrelado a EI é o modelo de gestão adotado pela rede. Desse modo, este artigo apresenta um recorte de um estudo de âmbito maior sobre a política e a gestão das creches da Secretaria Municipal de Educação (SMED) de Salvador- Bahia, realizado em 2023. Trata-se de uma pesquisa qualitativa do tipo documental na qual avaliamos as informações disponibilizadas pela SMED em sua rede oficial que versam sobre sua organização e infraestrutura. Verifica-se a função de cada setor, a relação entre eles e sua gestão, assim como a infraestrutura disponibilizada. Analisamos os dados encontrados frente ao posto na literatura, refletindo sobre a EI e apontando a necessidade dela como pauta da agenda das políticas de educação. Destarte, cabe as políticas educacionais abarcar de forma ampla e inclusiva a EI, uma vez que ela é um direito de todas as crianças desde o seu nascimento. Logo, se faz consoante às políticas de educação garantirem a sua oferta e expansão em nosso município a fim de atender as crianças de 0 a 3 anos.
Uso de óleo de cannabis no tratamento de sequela de cinomose: relato de caso
Authors:   , Prado Ana Blandina Cintra de Almeida
Published: August 2024

O presente estudo tem como objetivo apresentar o relato clínico da cadela sem raça definida, portadora de sequela neurológica de cinomose, e os resultados benéficos provenientes do uso do óleo de Cannabis utilizado em seu tratamento. A terapia proposta foi complementar, visto que, juntamente ao óleo de cannabis full spectrum foram mantidos o uso do fenobarbital e brometo de potássio. Medicações essas que tiveram as dosagens reduzidas após o início do uso do óleo. Foram notórias e significativas as evoluções do animal posteriormente ao início do tratamento com fitocanabinoides derivados da Cannabissativa, que possibilitou o cessar daadministração de alguns medicamentos e a diminuição da dose de outros, além da promoção do bem estar da cadela Sabrina, a qual apresentou melhora em todos os sinais clínicos que apresentava.
Uso da ozonioterapia para cicatrização de ferida em caprino: relato de caso
Authors:   , Dias Bianca Guaré , Nogueira Júlia Kocks
Published: August 2024

A ozonioterapia vem ganhando cada vez mais espaço como tratamento integrativo na Medicina Veterinária e se demonstra eficaz devido aos seus efeitos bactericidas de amplo espectro, que auxilia na limpeza e desinfecção de feridas infectadas. O presente trabalho tem como objetivo relatar o caso de um mini cabrito, macho, com 6 meses de idade, que apresentou lesão no flanco direito causada pela mordida de um cão e após um longo período de tratamento optou-se pela integração da ozonioterapia na forma de solução fisiológica ozonizada, óleo de girassol ozonizado e gás ozonizado no método Cupping. O tratamento revelou-se efetivo, sendo possível observar melhora rápida e redução total de toda a extensão da ferida, além de ser um tratamento de fácil aplicação que não gera incômodo para o paciente.
Hermafroditismo canino: relato de caso
Authors:   , Fernandes Isabelle
Published: August 2024

O hermafroditismo representa uma raridade em termos de condições de desenvolvimento do sistema reprodutivo na medicina veterinária, com sua causa ainda não totalmente compreendida, podendo ser de origem congênita ou genética. Animais afetados por essa condição exibem traços fenotípicos que não correspondem aos de seus tecidos gonadais. Este estudo descreve o caso de um cão Pinscher de dois anos que, apesar de mostrar sinais de estro, possuía genitália externa feminina e um pênis localizado no canal vaginal. Avaliações ultrassonográficas revelaram a presença de testículos, útero e ovários. Foram realizados procedimentos de laparotomia exploratória, orquiectomia e penectomia. Levando em conta os achados fenotípicos, ultrassonográficos e histológicos, determinou-se que o cão era um pseudohermafrodita masculino. A complexidade deste caso sublinha a necessidade de mais estudos para melhor entender as origens e implicações do hermafroditismo em animais, contribuindo assim para melhorar as práticas de diagnóstico e tratamento.
Hipoadrenocorticismo em cães: revisão bibliográfica
Authors:   , Souza Luiza Mendes de
Published: August 2024

O hipoadrenocorticismo é uma endocrinopatia definida como a deficiência na produção de glicocorticoides e/ou mineralocorticoides. É pouco comum em cães ou aparentemente subdiagnosticada, tendo causas primárias, secundárias e iatrogênica. Os sinais clínicos são pouco específicos e de grande variabilidade, podendo o paciente apresentar somente quadros esporádicos de hiporexia, vômitos e diarreia ou até mesmo choque hipovolêmico e óbito. O diagnóstico é baseado nos dados de anamnese, sinais clínicos, exames laboratoriais e de imagem, sendo o teste de estimulação com ACTH (hormônio adrenocorticotrófico) o teste hormonal de escolha para o diagnóstico da doença. O tratamento baseia-se na reposição hormonal exógena, com base na necessidade do paciente. Dessa forma, o objetivo desta revisão é alertar os clínicos sobre a importância desta doença, quando suspeitar e como realizar um diagnóstico preciso, assim como, diferenciar de outras enfermidades que possuem sintomatologia semelhante.
Avaliação neuro-histológica em ratos expostos ao colorante azafilona
Authors:   , Alves Mônica Rodrigues
Published: August 2024

A utilização de corantes na alimentação animal é comum na indústria de alimentos processados e a segurança desses aditivos é uma preocupação devido aos potenciais efeitos adversos. Como alternativa aos corantes sintéticos comerciais, corantes naturais estão sendo estudadas a partir de fontes como plantas, frutas e fungos. A azafilona, colorante vermelho oriundo do fungo Talaromyces mostra bom potencial como alternativa por demonstrar baixa citotoxicidade em testes in vitro. A avaliação da histologia neurológica em ratos expostos ao corante foi analisada nesse estudo. Para isso, 48 ratos Wistar, machos e fêmeas, foram divididos e expostos a diferentes doses da azafilona (250, 500 e 1000 mg/kg) durante 90 dias, comparados a um grupo controle. Após esse período, os ratos foram eutanasiados, e em seguida o tecido cerebelar foi coletado, fixado e corado em lâminas histológicas. Análise visual foi realizada em todas as lâminas, para verificação de alterações estruturais. Além disso, 5 campos corticais de cada lâmina foram avaliados quanto à quantidade de células de Purkinje. A exposição de ratos ao colorante azafilona resultou em uma diminuição significativa no número de células de Purkinje no cerebelo acompanhada por alterações morfológicas degenerativas como achatamento celular e desorganização da camada. Diante disso, sugere-se que a azafilona induz alterações neurológicas, ou seja, tem efeitos adversos sobre o sistema nervoso central, especialmente nas células cerebelares. Entretanto, vale ressaltar que, para colorir alimentos e outros produtos pet, baixas concentrações de corantes são utilizadas, e mesmo a menor concentração estudada aqui (250 mg/kg de animal) ainda é uma concentração elevada se pensarmos na necessidade para colorir soluções e alimentos.
Técnicas complementares empregadas na reabilitação de ovino com hipoxia neonatal: relato de caso
Authors:   , Santos Roberta Rodrigues Pires
Published: August 2024

A Hipóxia Neonatal é a privação de oxigênio que leva a lesão no sistema nervoso central, é causada por diversos problemas gestacionais com mais recorrência em partos distócicos. O presente relato de caso vem demostrar técnicas complementares como acupuntura, laserterapia, entre outras, que foram utilizadas para amenizar sequelas da hipóxia em ovino neonato, com tetraparesia, não ambulatória, tendo como causas sequelas de hipoxia cerebral. Observou-se benefício das técnicas empregadas com a melhora dos parâmetros neurológicos e ausência de efeitos colaterais durante e após os procedimentos.
Employee Ratings and Reviews Data from Glassdoor
Authors: Zhou Mi , Li Yaxuan , Qiao Zhilei , Shi Bowen
Published: August 2024

This paper presents the employee ratings and reviews data from Glassdoor and the R codes used to collect, clean, and organize the data. We collect three types of information for each Glassdoor review: review metrics, content, and reviewer information. We also calculate some commonly used textual metrics, such as sentiment, readability, the number of uncertainty words, etc. The datasets include necessary identifiers that can connect to other financial data sources. All the variables and metrics are provided at the review level, which enables researchers to aggregate the data from different levels and angles. As a demonstrative example, we use a simple word list to measure how often employees mention COVID-19 in review comments. The R codes provided as an RStudio project are self-contained and can also be modified and applied to other data sources of interest.
UJI EFEKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L.) PADA TIKUS JANTAN GALUR WISTAR
Authors: Norhikami Norhikami , Fadhilah Arini
Published: August 2024

Inflamasi adalah respon imun tubuh yang bekerja terhadap rangsangan fisik, kimia, maupun zat berbahaya atau mikrobiologi. Obat antiinflamasi golongan NSAID (Nonsteroidal Anti-Inflammatory Drugs) atau golongan steroid umumnya mempunyai banyak efek samping. Daun kelor (Moringa oleifera L.) adalah tanaman tropis yang bisa dijadikan referensi alternatif dalam menurunkan peradangan. Penelitian ini bertujuan untuk menguji efektivitas antiinflamasi daun kelor pada tikus jantan galur Wistar yang diinjeksi subplantar dengan karagenin 1%. Lima kelompok perlakuan masing-masing 5 ekor tikus jantan galur Wistar dengan bobot antara 150-250 gram. Kelompok I Na-CMC 0,5% (kontrol negatif) digunakan sebagai pembanding dan pembawa untuk pembuatan larutan kontrol positif dan larutan ekstrak uji, kelompok II natrium diklofenak 15 mg/KgBB (kontrol positif), dan sebagai kelompok perlakuan yaitu kelompok III, IV, dan V diberi ekstrak etanol daun kelor (EEDK) dosis 25, 50, dan 100 mg/KgBB. Pengamatan dilakukan selama 6 jam dari jam ke-0, 1, 2, 3, 4, 5, dan 6 dengan mengukur tebal udema kaki tikus dengan jangka sorong digital, kemudian dihitung rata-rata ± SD (mm). Data dianalisis dengan SPSS uji statistik ANOVA dan uji lanjut LSD. Ekstrak etanol daun kelor (EEDK) dosis 25, 50, dan 100 mg/KgBB mempunyai aktivitas antiinflamasi dalam menurunkan udema kaki tikus. Dosis 100 mg/KgBB mempunyai aktivitas penurunan inflamasi paling baik dan rata-rata penurunan inflamasinya pada jam ke-1 hingga ke-6 menunjukkan  nonsignifikan (p > 0,05) dengan tebal udem paling rendah pada jam ke-6 yaitu 4,82±0,10 mm sebanding dengan kontrol positif (4,81±0,17 mm). Ekstrak etanol daun kelor disimpulkan memiliki efektivitas antiinflamasi dalam menurunkan peradangan pada udema kaki tikus.
EVALUASI DRUG RELATED PROBLEM (DRPs) PADA PASIEN DEMAM TIFOID DI INSTALASI RAWAT INAP RSU ISLAM KLATEN PERIODE NOVEMBER 2021-OKTOBER 2022
Authors: Marisya Affifah Putri Nabilla , Fortuna Tista Ayu , Yudianti Mendra Ni Nyoman
Published: August 2024

Demam tifoid adalah suatu penyakit yang disebabkan oleh infeksi organisme Salmonella typhi. Ketidaktepatan pemberian terapi pada pasien dapat meningkatkan resiko kejadian Drug Related Problems (DRPs). Tingginya kejadian (DRPs) dapat mempengaruhi keberhasilan terapi pada pasien, sehingga penelitian ini sangat penting untuk dilakukan. Tujuan penelitian ini adalah untuk mengetahui bagaimana tingkat kejadian DRPs yang meliputi kategori efek samping, interaksi pengobatan, dosis terlalu rendah serta dosis terlalu tinggi pada pasien demam tifoid di instalasi rawat inap periode November 2021-Oktober 2022. Penelitian ini merupakan penelitian non-eksperimental dengan pengambilan data secara retrospektif, dimana peneliti akan mengevaluasi pengobatan demam tifoid yang didapatkan oleh pasien. Pengambilan sampel dilakukan dengan teknik total sampling berdasarkan kriteria inklusi pasien meliputi usia lebih dari 18 tahun, pasien demam tifoid dengan atau tanpa penyakit penyerta dan pasien dengan rekam medis yang lengkap. Kiteria eksklusi meliputi pasien dengan data rekam medis yang tidak terbaca dan pasien dengan penyakit penyerta infeksi. Berdasarkan hasil penelitian terhadap 67 pasien, sebanyak 36 pasien (53,73%) mengalami DRPs dan 31 pasien (46,27%) tidak mengalami DRPs. Antibiotik yang paling banyak digunakan adalah levofloksasin 67 pasien (100%), kemudian diikuti dengan ampisilin 3 pasien (4,48%) serta sefiksim 3 pasien (4,48%). Penggunaaan terapi suportif yang paling banyak diberikan adalah parasetamol 67 pasien (100%). Jumlah DRPs yang terjadi sebanyak 65 kasus dengan rincian kategori dosis terlalu rendah 13 kasus (20%), dosis terlalu tinggi 2 kasus (3,08%), efek samping 14 kasus (21,54%), dan interaksi obat 36 kasus (55,38%).
EVALUASI DRUG RELATED PROBLEMS PADA PASIEN INFEKSI SALURAN KEMIH RAWAT INAP DI RUMAH SAKIT DAERAH SURAKARTA TAHUN 2022
Authors: Rachim Hanessa Febriani Farisca , Nugraheni Ambar Yunita
Published: August 2024

Infeksi saluran kemih merupakan penyakit adanya mikroorganisme didalam urin yang berpotensi menyerang saluran kemih. Prevalensi ISK menurut Departemen Kesehatan Republik Indonesia tahun 2014 terdapat sekitar 180.000 kasus per tahun. Terapi ISK paling utama adalah antibiotik dan seringkali disertai terapi suportif. Penggunaan terapi memungkinkan terjadinya drug related problems yang menyebabkan kegagalan pengobatan sehingga perlu dievaluasi untuk dapat meningkatkan ketepatan dalam penggunaan terapi. Penelitian ini bertujuan untuk mengetahui tingkat kejadian drug related problems meliputi masalah obat terkait indikasi (indikasi tanpa obat dan obat tanpa indikasi); efektivitas terapi (ketidaktepatan penggunaan obat dan kontraindikasi), dosis (dosis kurang dan dosis lebih) dan interaksi obat pada pasien ISK rawat inap di RSUD Dr. Moewardi Tahun 2022. Jenis penelitian ini adalah non eksperimental dan dianalisis secara deskriptif. Teknik pengambilan sampel dengan metode purposive sampling, dengan kriteria inklusi yaitu pasien anak maupun dewasa yang menjalani rawat inap dengan diagnosa ISK atau sistitis, pasien tanpa diagnosa infeksi lain, pasien memperoleh minimal 2 obat, memiliki data rekam medik lengkap meliputi nomor rekam medik, identitas pasien (nama, jenis kelamin, usia, dan berat badan (untuk anak)), diagnosis, gejala, data karakteristik obat (nama obat, dosis, frekuensi, rute dan tanggal pemberian), dan hasil laboratorium (jika ada). Data dianalisis berdasarkan pedoman IAUI (2020), Kulkarni (2019), BNF (2021), BNFC (2019), MIMS (2023), Drug Interaction Checker (drugs.com), dan Stockley Drug Interaction Handbook (2008). Hasil penelitian dari 97 pasien infeksi saluran kemih di RSUD Dr. Moewardi Tahun 2022 menunjukkan bahwa jumlah angka kejadian drug related problems indikasi tanpa obat (8,25%), obat tanpa indikasi (23,71%), ketidaktepatan penggunaan obat (3,09%), kontraindikasi (5,15%), dosis kurang (22,68%), dosis lebih (29,90%), interaksi obat (78,35%).
GAMBARAN TERAPI ANTIHIPERTENSI PADA PASIEN RAWAT JALAN DI RST. DR. ASMIR SALATIGA
Authors: Putri Nanda Ariyanto , Oktianti Dian
Published: August 2024

Peningkatan tekanan darah sistolik dan tekanan darah diastolik ≥140 mmHg/ ≥90 mmHg setelah dua kali pengukuran secara terpisah dapat disebut sebagai hipertensi. Pengobatan hipertensi tunggal dan hipertensi disertai diabetes mellitus memerlukan perhatian khusus. Penelitian ini bertujuan untuk mengetahui gambaran obat antihipertensi yang digunakan pada pasien rawat jalan yang menderita hipertensi tunggal serta hipertensi dan diabetes mellitus (DM) tipe 2. Penelitian deskriptif dengan pengambilan data rekam medis secara retrospektif. Kriteria inklusi penelitian ini adalah pasien hipertensi rawat jalan usia 26-65 tahun pada bulan Mei-Juni tahun 2023, sedangkan kriteria eksklusi adalah data rekam medis yang tidak lengkap. Data diambil secara purpossive sampling, dan diperoleh 60 rekam medis yang memenuhi kriteria. Sebanyak 53,33% penderita hipertensi tunggal adalah perempuan dan 53,33% hipertensi dengan DM tipe 2 diderita oleh laki-laki, serta banyak dialami pada usia 56-65 tahun. Pada pasien hipertensi tunggal menggunakan 1 obat (16,67%), 2 obat (70%) dan 3 obat (13,33%). Pasien hipertensi dengan DM tipe 2 menggunakan 1 obat (46,66%), 2 obat (36,67%) dan 3 obat (16,67%). Obat yang digunakan pada kedua kelompok adalah golongan diuretik, CCB, ARB dan beta-blocker. Penggunaan obat antihipertensi pada pasien hipertensi tunggal yang paling banyak yaitu 2 obat CCB + ARB (70%) dan untuk hipertensi dengan DM tipe 2 paling banyak menggunakan 1 obat yaitu ARB (33,33%).
Program Merdeka Belajar Kampus Merdeka Untuk Meningkatkan Micro-Skill Lulusan
Authors: Arifin Agus , Puspitorini Puput , Santosa Cecep Anwar H.F. , Ruhiat Yayat
Published: August 2024

Merdeka Belajar—Free Campus (MBKM) is a major step towards transforming Indonesia's higher education system. MBKM adopts the idea of independent learning, provides curriculum flexibility, allows students to participate in learning outside the study program, and encourages close collaboration between universities, the business world and the world of work. So that MBKM becomes an effective forum for students to develop hard skills, soft skills and micro-skills. This research design uses a quantitative with correlational design to measure the relationship between variables. Population and Sample: 87 students in the Serang Regency, Tangerang Regency and Tangerang City, Banten Province, Indonesia. R-Square: The R-square value for Micro-Skills is 0.205 and for Curriculum Development is 0.217, indicating the moderate ability of the model in explaining data variability. Lower Adjusted R-square values (Micro-Skills: 0.166, Curriculum Development: 0.189) indicate model adjustment for the number of predictor variables. F-square: The effect size of the exogenous latent variable on the endogenous latent variable shows a significant contribution of Academic Culture to Curriculum Development (f-square: 0.221), while other relationships are less significant. Path Coefficient: A statistically significant relationship was only found between Academic Culture and Curriculum Development (P = 0.019). Other relationships, such as Social Culture and Ethnocentrism with Micro-Skills or Curriculum Development, did not show statistical significance. MBKM gives students the opportunity to improve social skills, self-management abilities, and the ability to adapt to the work environment. Graduates can develop micro-skills thanks to curriculum flexibility and collaboration with industry. Universities can improve MBKM by focusing on learning relevant to industry demands and field experiences such as internships or practical projects.
New crops in the region of Vojvodina (Serbia) as "Rays of hope"
Authors: Lukić Tamara , Đečan Bojan , Bubalo Živković Milka , Bjelajac Dajana
Published: August 2024

The paper discusses phenomena in the rural area of the Vojvodina Region, which are recognized as opportunities that contribute to the balancing of regional development. The selection of phenomena is the result of clues about them found in the media. Through field observations and communication with the local population, knowledge about phenomena has been enriched. The task of the paper is to highlight the emergence of new, but also the renewal of old agricultural cultures that can be called new rural potentials. The importance of the work is to draw scientific attention to these "rays of hope", as the interlocutors called them during the research, and to highlight the need for continued monitoring because they can change certain natural and social characteristics of the Vojvodina Region.
Evaluation of the recreation attractiveness of the Banská Štiavnica water reservoirs
Authors: Petráš Ján
Published: August 2024

Most of the water reservoirs in Banská Štiavnica and its surroundings were built for mining, which was a major economic force in this area for centuries. While in the past these reservoirs, called tajchs were used precisely for mining purposes, nowadays, with the almost extinct mining activity, they have found a new application, primarily in the field of recreation. However, not all tajchs are equally attractive to visitors. The subject of interest in our contribution was therefore the evaluation of the recreation attractiveness of the Banská Štiavnica water reservoirs from the point of view of tourism. The evaluation was created using the valorization method, based on the materials obtained through bibliographic, field and questionnaire research. The results of the evaluation can be used in the development of tourism in localities of water reservoirs, since their attractiveness is directly related to the development of tourism.
Behavioral insights into reusable bag adoption: Evaluating the effectiveness of the theory of planned behavior in Lahore
Authors: Atif Rao Muhammad , Ahmed Faraz , Khan Muhammad , Amir-ud-Din Rafi
Published: August 2024

Reusable bags have been introduced as an alternative to single-use plastic bags (SUPB). While beneficial, this alternative is economically and environmentally viable only if utilized multiple times. This study aims to identify the determinants influencing the use of reusable bags (RB) over single-use plastic bags (SUPB) within the framework of ecological impact reduction, employing the Theory of Planned Behavior (TPB). The focus is on understanding how attitudes (AT), subjective norms (SN), and perceived behavioral control (PBC) collectively guide consumers towards adopting reusable bags as a pro-environmental choice. The focus is on understanding how attitudes (AT), subjective norms (SN), and perceived behavioral control (PBC) collectively guide consumers towards the adoption of reusable bags as a pro-environmental choice. Data were collected through a survey administered to 814 consumers in Lahore, employing both regression analysis and Structural Equation Modeling (SEM) to assess the impact of AT, SN, and PBC on reusable bag consumption (RBC). The TPB framework underpins the hypothesis that these three psychological factors significantly influence the decision to use RBs. Both regression and SEM analyses demonstrated that AT, SN, and PBC positively affect RBC, with significant estimates indicating the strength of each predictor. Specifically, PBC emerged as the strongest predictor of RBC (PBC2, β = 0.533, p < 0.001), highlighting the paramount importance of control perceptions in influencing bag use. This was followed by AT (β = 0.211, p < 0.001) and SN (β = 0.173, p < 0.001), confirming the hypothesized positive relationships. The congruence of findings from both analytical approaches underlines the robustness of these techniques in validating the TPB within the context of sustainable consumer behaviors. The investigation corroborates the TPB’s applicability in predicting RBC, with a clear hierarchy of influence among the model’s constructs. PBC’s prominence underscores the necessity of enhancing consumers’ control over using RBs to foster sustainable consumption patterns. Practical implications include the development of policies and marketing strategies that target the identified determinants, especially emphasizing the critical role of PBC, to promote broader adoption of RBs and contribute to significant reductions in plastic waste.