bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Fig. S4 from SHP and Sin3A expression are essential for adamantyl-substituted retinoid-related molecule–mediated nuclear factor-κB activation, c-Fos/c-Jun expression, and cellular apoptosis
Authors: Farhana Lulu , Dawson Marcia I. , Xu Liping , Dannenberg Jan-Hermen , Fontana Joseph A.
Published: April 2023

Supplementary Fig. S4 from SHP and Sin3A expression are essential for adamantyl-substituted retinoid-related molecule–mediated nuclear factor-κB activation, c-Fos/c-Jun expression, and cellular apoptosis
Supplementary Fig. S3 from SHP and Sin3A expression are essential for adamantyl-substituted retinoid-related molecule–mediated nuclear factor-κB activation, c-Fos/c-Jun expression, and cellular apoptosis
Authors: Farhana Lulu , Dawson Marcia I. , Xu Liping , Dannenberg Jan-Hermen , Fontana Joseph A.
Published: April 2023

Supplementary Fig. S3 from SHP and Sin3A expression are essential for adamantyl-substituted retinoid-related molecule–mediated nuclear factor-κB activation, c-Fos/c-Jun expression, and cellular apoptosis
Supplementary Fig. S1 from A selective small-molecule nuclear factor-κB inhibitor from a high-throughput cell-based assay for “activator protein-1 hits”
Authors: Kang Moon-Il , Henrich Curtis J. , Bokesch Heidi R. , Gustafson Kirk R. , McMahon James B. , Baker Alyson R. , Young Matthew R. , Colburn Nancy H.
Published: April 2023

Supplementary Fig. S1 from A selective small-molecule nuclear factor-κB inhibitor from a high-throughput cell-based assay for “activator protein-1 hits”
Supplementary Methods and References from Aflibercept Exerts Antivascular Effects and Enhances Levels of Anthracycline Chemotherapy In vivo in Human Acute Myeloid Leukemia Models
Authors: Lal Deepika , Park Jennifer A. , Demock Kellie , Marinaro Joseph , Perez Amanda M. , Lin Mei-Hui , Tian Lili , Mashtare Terry J. , Murphy Michael , Prey Joshua , Wetzler Meir , Fetterly Gerald J. , Wang Eunice S.
Published: April 2023

Supplementary Methods and References from Aflibercept Exerts Antivascular Effects and Enhances Levels of Anthracycline Chemotherapy In vivo in Human Acute Myeloid Leukemia Models
Supplementary Figure Legends from Aflibercept Exerts Antivascular Effects and Enhances Levels of Anthracycline Chemotherapy In vivo in Human Acute Myeloid Leukemia Models
Authors: Lal Deepika , Park Jennifer A. , Demock Kellie , Marinaro Joseph , Perez Amanda M. , Lin Mei-Hui , Tian Lili , Mashtare Terry J. , Murphy Michael , Prey Joshua , Wetzler Meir , Fetterly Gerald J. , Wang Eunice S.
Published: April 2023

Supplementary Figure Legends from Aflibercept Exerts Antivascular Effects and Enhances Levels of Anthracycline Chemotherapy In vivo in Human Acute Myeloid Leukemia Models
Supplementary Figure 1 from Nanaomycin A Selectively Inhibits DNMT3B and Reactivates Silenced Tumor Suppressor Genes in Human Cancer Cells
Authors: Kuck Dirk , Caulfield Thomas , Lyko Frank , Medina-Franco Jose L.
Published: April 2023

Supplementary Figure 1 from Nanaomycin A Selectively Inhibits DNMT3B and Reactivates Silenced Tumor Suppressor Genes in Human Cancer Cells
Supplementary Data from An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance
Authors: Mitra Doyel , Brumlik Michael J. , Okamgba Stella U. , Zhu Yun , Duplessis Tamika T. , Parvani Jenny G. , Lesko Samuel M. , Brogi Edi , Jones Frank E.
Published: April 2023

Supplementary Data from An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance
Supplementary Table 1 from Phase II Trial to Evaluate Gemcitabine and Etoposide for Locally Advanced or Metastatic Pancreatic Cancer
Authors: Melnik Marianne K. , Webb Craig P. , Richardson Patrick J. , Luttenton Charles R. , Campbell Alan D. , Monroe Thomas J. , O'Rourke Timothy J. , Yost Kathleen J. , Szczepanek Connie M. , Bassett Michelle R. , Truszkowski Kimberly J. , Stein Phyllis , Van Brocklin Matthew W. , Davis Alan T. , Bedolla Gabriela , Vande Woude George F. , Koo Han-Mo
Published: April 2023

Supplementary Table 1 from Phase II Trial to Evaluate Gemcitabine and Etoposide for Locally Advanced or Metastatic Pancreatic Cancer
Supplementary Fig. S5 from Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity
Authors: Valli Claudia , Paroni Gabriela , Di Francesco Angela Maria , Riccardi Riccardo , Tavecchio Michele , Erba Eugenio , Boldetti Andrea , Gianni' Maurizio , Fratelli Maddalena , Pisano Claudio , Merlini Lucio , Antoccia Antonio , Cenciarelli Chiara , Terao Mineko , Garattini Enrico
Published: April 2023

Supplementary Fig. S5 from Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity
Supplementary Tables 1-6 from BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
Authors: Carboni Joan M. , Wittman Mark , Yang Zheng , Lee Francis , Greer Ann , Hurlburt Warren , Hillerman Stephen , Cao Carolyn , Cantor Glenn H. , Dell-John Janet , Chen Cliff , Discenza Lorell , Menard Krista , Li Aixin , Trainor George , Vyas Dolatrai , Kramer Robert , Attar Ricardo M. , Gottardis Marco M.
Published: April 2023

Supplementary Tables 1-6 from BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
Supplementary Figure 2 from BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
Authors: Carboni Joan M. , Wittman Mark , Yang Zheng , Lee Francis , Greer Ann , Hurlburt Warren , Hillerman Stephen , Cao Carolyn , Cantor Glenn H. , Dell-John Janet , Chen Cliff , Discenza Lorell , Menard Krista , Li Aixin , Trainor George , Vyas Dolatrai , Kramer Robert , Attar Ricardo M. , Gottardis Marco M.
Published: April 2023

Supplementary Figure 2 from BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
Supplementary Data from From NPC Therapeutic Target Identification to Potential Treatment Strategy
Authors: Lan Ming-Ying , Chen Chi-Long , Lin Kuan-Ting , Lee Sheng-An , Yang Wu-Lung R. , Hsu Chun-Nan , Wu Jaw-Ching , Ho Ching-Yin , Lin Jin-Ching , Huang Chi-Ying F.
Published: April 2023

Supplementary Data from From NPC Therapeutic Target Identification to Potential Treatment Strategy
Supplementary Fig. S1 from KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo
Authors: Hassig Christian A. , Symons Kent T. , Guo Xin , Nguyen Phan-Manh , Annable Tami , Wash Paul L. , Payne Joseph E. , Jenkins David A. , Bonnefous Céline , Trotter Carol , Wang Yan , Anzola John V. , Milkova Elena L. , Hoffman Timothy Z. , Dozier Sara J. , Wiley Brandon M. , Saven Alan , Malecha James W. , Davis Robert L. , Muhammad Jerry , Shiau Andrew K. , Noble Stewart A. , Rao Tadimeti S. , Smith Nicholas D. , Hager Jeffrey H.
Published: April 2023

Supplementary Fig. S1 from KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo
Supplementary Movie S4 from Induction of apoptosis by monastrol, an inhibitor of the mitotic kinesin Eg5, is independent of the spindle checkpoint
Authors: Chin Gregory M. , Herbst Ronald
Published: April 2023

BubR1 siRNA Taxol
Supplementary Figure 2 from Improved low molecular weight Myc-Max inhibitors
Authors: Wang Huabo , Hammoudeh Dalia I. , Follis Ariele Viacava , Reese Brian E. , Lazo John S. , Metallo Steven J. , Prochownik Edward V.
Published: April 2023

Supplementary Figure 2 from Improved low molecular weight Myc-Max inhibitors
Supplementary Fig. S1 from Antitumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane type 1-matrix metalloproteinase
Authors: Zhong Jieying , Chau Ying
Published: April 2023

Supplementary Fig. S1 from Antitumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane type 1-matrix metalloproteinase
Data from Phase I safety, pharmacokinetic, and pharmacogenomic trial of ES-285, a novel marine cytotoxic agent, administered to adult patients with advanced solid tumors
Authors: Baird Richard D. , Kitzen Jos , Clarke Paul A. , Planting Andre , Reade Sarah , Reid Alison , Welsh Lyndsey , López Lázaro Luis , de las Heras Begona , Judson Ian R. , Kaye Stan B. , Eskens Ferry , Workman Paul , deBono Johann S. , Verweij Jaap
Published: April 2023

Abstract
A dose-escalation, phase I study evaluated the safety, pharmacokinetics, pharmacogenomics, and efficacy of ES-285, a novel agent isolated from a marine mollusc, in adult cancer patients. Patients received a 24-hour i.v. infusion of ES-285 once every 3 weeks until disease progression or unacceptable toxicity. The starting dose was 4 mg/m2. Dose escalation in cohorts of at least three patients proceeded according to the worst toxicity observed in the previous cohort. Twenty-eight patients were treated with 72 courses of ES-285 across eight dose levels. No dose-limiting toxicities were seen between 4 and 128 mg/m2. Two of four patients treated at 256 mg/m2 had dose-limiting reversible grade 3 transaminitis; one patient at 256 mg/m2 also had transient grade 3 central neurotoxicity. One of three patients subsequently treated at 200 mg/m2 died following drug-related central neurotoxicity. Other toxicities included phlebitis, nausea, fatigue, and fever. Pharmacokinetic studies indicated dose proportionality with high volume of distribution (median Vss at 256 mg/m2 was 2,389 liters; range, 1,615–4,051 liters) and long elimination half life (median t1/2 at 256 mg/m2 was 28 h; range, 21–32 h). The three patients with dose-limiting toxicity had the highest drug exposure. Pharmacogenomic studies of paired surrogate tissue samples identified changes in gene expression following treatment that correlated with increasing dose. Disease stabilization for 6 to 18 weeks was recorded in nine patients. Using this schedule, 128 mg/m2 was considered safe and feasible. At this dose, pharmacologically relevant concentrations of the drug were safely achieved with pharmacogenomic studies indicating changes in the expression of genes of potential mechanistic relevance. [Mol Cancer Ther 2009;8(6):1430–7]
Data from Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions
Authors: Gopal Y.N. Vashisht , Chanchorn Ekkawit , Van Dyke Michael W.
Published: April 2023

Abstract
MDM2 belongs to a class of ring-finger domain–containing ubiquitin ligases that mediate the proteasomal degradation of numerous proteins, including themselves. Arguably, the most important substrate of MDM2 is p53, which controls cell cycle progression and apoptosis. MDM2 and p53 are parts of a feedback regulatory loop whose perturbations are often present in cancer and are targets for anticancer drug development. We found that the natural product, small-molecule anti-inflammatory agent parthenolide (PN), which is actively being investigated as a potential therapeutic for many human cancers, induces ubiquitination of MDM2 in treated cells, resulting in the activation of p53 and other MDM2-regulated tumor-suppressor proteins. Using cells with functional gene deletions and small interfering RNA knockdown studies, we found that these effects required the DNA damage transducer ataxia telangiectasia mutated. The effects of PN on tumor suppressor activation were comparable with that of nutlin-3a, a recently developed small molecule that was designed to interfere with the interaction between MDM2 and p53 but does not promote MDM2 ubiquitination. Our study illustrates an alternative approach for controlling MDM2 and p53 activities and identifies an additional critically important cancer pathway affected by PN. [Mol Cancer Ther 2009;8(3):552–62]
Data from Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines
Authors: Crea Francesco , Giovannetti Elisa , Cortesi Filippo , Mey Valentina , Nannizzi Sara , Gallegos Ruiz Marielle I. , Ricciardi Simona , Del Tacca Mario , Peters Godefridus J. , Danesi Romano
Published: April 2023

Abstract
Irinotecan is a topoisomerase-I (Top-I) inhibitor used for the treatment of colorectal cancer. DNA demethylating agents, including 5-azacytidine (5-aza), display synergistic antitumor activity with several chemotherapy drugs. 5-Aza may enhance irinotecan cytotoxicity by at least one of the following mechanisms: (a) Top-I promoter demethylation, (b) activation of genes involved in Top-I transcriptional regulation (p16 or Sp1), and (c) modulation of the cell cycle and apoptosis after DNA damage. The growth-inhibitory effects of SN38, the active metabolite of irinotecan, 5-aza, and their combinations, were studied in four colorectal cancer cell lines. The effects of treatments on cell cycle were analyzed by flow cytometry, and apoptosis was measured by fluorescence microscopy. Top-I, Sp1, and p53 expression modulated by 5-aza were measured by real-time PCR. Methylation of Top-I, p16, 14-3-3σ, and hMLH1 promoters before and after 5-aza treatment were measured by MethyLight PCR and DNA bisulfite sequencing. Low-dose 5-aza significantly enhanced the apoptotic effect of irinotecan in all colorectal cancer cells, whereas a synergistic cytotoxic effect was observed only in p53-mutated cells (HT29, SW620, and WiDr). This synergistic effect was significantly correlated with Top-I up-regulation by 5-aza, and coupled to p16 demethylation and Sp1 up-regulation. p16 demethylation was also associated with enhanced cell cycle arrest after irinotecan treatment. In contrast, 5-aza down-regulated Top-I expression in the p53 wild-type LS174T cells in a p53-dependent manner, thereby reducing SN38 cytotoxicity. In conclusion, 5-aza modulates Top-I expression by several mechanisms involving Sp1, p16, and p53. If confirmed in other models, these results suggest that p16 and p53 status affects the 5-aza–irinotecan interaction. [Mol Cancer Ther 2009;8(7):1964–73]
Data from Demonstration of the equivalent pharmacokinetic/pharmacodynamic dosing strategy in a multiple-dose study of gefitinib
Authors: Wang Shining , Zhou Qingyu , Gallo James M.
Published: April 2023

Abstract
The goals of this investigation were to illustrate the use of pharmacokinetic (PK)/pharmacodynamic (PD) modeling strategies in drug development based on a multiple-dose study of gefitinib in a preclinical tumor model. Mice bearing s.c. LN229-wild-type epidermal growth factor receptor or LN229-EGFRvIII mutant (a sensitizing mutation) tumors were administered gefitinib at oral doses of either 55 mg/kg/d p.o. × 15 days or 30 mg/kg/d p.o. × 15 days, respectively, as dictated by the equivalent PK/PD dosing strategy. In each tumor group, gefitinib plasma and tumor concentrations were quantitated, as well as the tumoral amounts of phosphorylated-extracellular signal-regulated kinase 1/2 (pERK), a selected PD end point, and tumor size. The resultant data provided the basis to develop hybrid physiologically based PK/PD/tumor growth models for each tumor type. It was found that the 1.83-fold dose difference administered to the two tumor groups resulted in analogous pERK profiles on both days 1 and 15, and further induced similar antitumor efficacy based on tumor size. In addition, using brain tumor patient PK data linked to the pERK PD model, simulations were conducted to illustrate potential applications of a target tumor model to patients. The simulations provided insight on the relationships between blood-brain barrier penetration, brain tumor gefitinib concentrations, and the extent of inhibition of pERK. The implementation of the PK/PD equivalent dosing strategy offers a new approach to drug development. [Mol Cancer Ther 2009;8(6):1438–47]
Data from A selective small-molecule nuclear factor-κB inhibitor from a high-throughput cell-based assay for “activator protein-1 hits”
Authors: Kang Moon-Il , Henrich Curtis J. , Bokesch Heidi R. , Gustafson Kirk R. , McMahon James B. , Baker Alyson R. , Young Matthew R. , Colburn Nancy H.
Published: April 2023

Abstract
NSC 676914 has been identified as a selective nuclear factor-κB (NF-κB) inhibitor that does not inhibit cell proliferation. This compound was originally identified in a high-throughput cell-based assay for activator protein-1 (AP-1) inhibitors using synthetic compound libraries and the National Cancer Institute natural product repository. NSC 676914 shows activity against NF-κB in luciferase reporter assays at concentrations much less than the IC50 for AP-1. A serum response element reporter used as a specificity control and indicator of cell proliferation was relatively insensitive to the compound. Pretreatment with NSC 676914 is here shown to repress 12-O-tetradecanoylphorbol-13-acetate (TPA)–induced IκB-α phosphorylation and translocation of p65/50 to the nucleus but not the processing of p52 from p100, suggesting the inhibition of NF-κB regulator IKKβ rather than IKKα. Inhibition of NF-κB activation occurred as a consequence of blocking phosphorylation of IKK. Induction of IκB-α phosphorylation by TPA was diminished by pretreatment of NSC 676914 even at 1.1 μmol/L. In contrast, kinases c-Jun-NH2-kinase and extracellular signal-regulated kinases 1 and 2, important for AP-1 activation, showed no significant repression by this compound. Furthermore, a Matrigel invasion assay with breast cancer cell lines and a transformation assay in mouse JB6 cells revealed that TPA-induced invasion and transformation responses were completely repressed by this compound. These results suggest that NSC 676914 could be a novel inhibitor having potential therapeutic activity to target NF-κB for cancer treatment or prevention. [Mol Cancer Ther 2009;8(3):571–81]
Polki z Pomorza wśród więźniarek „wychowawczych” Arbeitserziehungslager Stutthof
Authors: Drywa Danuta
Published: April 2023

Wprowadzenie przez okupanta niemieckiego obowiązku pracy przymusowej spowodowało, że niedopełnienie zameldowania się w niemieckim urzędzie pracy (Arbeitsamt), jak i niepodjęcie przez nich pracy w określonym terminie karane było zatrzymaniem i osadzeniem na tzw. wychowanie w obozie pracy wychowawczej (Arbeitserziehungslager Stutthof) na okres od dwóch do sześciu lub więcej tygodni. Wśród młodych więźniarek AEL Stutthof znajdowały się kobiety z całego Pomorza Gdańskiego kierowane przymusowo do pracy na roli, w mniejszych zakładach produkcyjnych lub zatrudniane jako pomoce domowe. Zwolnienie z obozu nie oznaczało powrotu do domu, lecz ponowne skierowanie do urzędu pracy.
Robotnicy cywilni w KL Auschwitz w latach 1940–1945
Authors: Hojka Zbigniew
Published: April 2023

Na terenie KL Auschwitz oraz w kopalniach i hutach, przy których istniały filie obozu, obok więźniów pracowali również robotnicy cywilni. Z reguły zatrudniani byli za pośrednictwem prywatnych firm. Pochodzili z Niemiec, państw sojuszniczych III Rzeszy oraz krajów okupowanych. W pierwszym okresie zatrudniano przede wszystkim fachowców, później także pracowników niewykwalifikowanych. Ich warunki zakwaterowania i wyżywienia były najczęściej fatalne. Angażowali się w pomoc więźniom, głównie poprzez dostarczanie żywności i lekarstw. Pewna ich część przynależała do organizacji konspiracyjnych.
Polityka przesiedleńcza Międzynarodowej Organizacji ds. Uchodźców – nowe podejście społeczności międzynarodowej do problemu uchodźców w Europie: studium przypadku przesiedleńców i uchodźców z Polski
Authors: Sękowski Paweł
Published: April 2023

Międzynarodowa Organizacja do spraw Uchodźców (IRO) działała w latach 1947– 1951 jako wyspecjalizowana agencja ONZ. Praca IRO była kontynuacją akcji humanitarnych organizowanych wcześniej na rzecz przesiedleńców (DP, dipisi) i uchodźców przez UNRRA i IGCR. Celem artykułu jest analiza polityki przesiedleńczej IRO jako wyznacznika nowego podejścia społeczności międzynarodowej do postępowania z przesiedleńcami i uchodźcami na przykładzie osób tych kategorii z Polski, którzy stanowili największą grupę narodową objętą opieką IRO w Europie.
Invasion of Parthenocissus quinquefolia (L.) Planch in the forest-steppe of Ukraine
Authors: Blinkova Olena , Makarenko Natalia , Raichuk Liudmila , Havrylnuk Yulia , Grabovska Tetiana , Roubik Hynek
Published: April 2023

Research needs of adaptation mechanisms of invasive alien species arises in connection with the naturalization of species of the genus Parthenocissus Planch in forest ecosystems of Ukraine. The results showed that P. quinquefolia has a wide range of values of edaphic and climatic factors. The populations of P. quinquefolia differ according to the degree of anthropogenic transformation of the ecotope, the ecological conditions formed, and the allocation of coenotics. The biomorphological characteristics of the species variability are shown on the gradient of anthropogenic transformation. Diagnostic parameters of P. quinquefolia under the conditions of anthropogenic transformation are the number of crotches of the tendrils and the length of the tendrils. The number of flowers per plant is characterized by the highest level of variation and belongs to the V class of variability. The smallest plasticity is characterized by the diameter of the stem. Vitality analysis indicated that cenopopulations of P. quinquefolia belong to the equilibria or prosperous population types, regardless of the intensity of the anthropogenic factor.
Allometric relationships among tree-size variables under tropical forest stages in Gia Lai, Vietnam
Authors: Bui Manh Hung , Phung Van Khoa , Nguyen Thi Bich Phuong , Nguyen Van Quy , Dell Bernard
Published: April 2023

Allometric models play an undeniable role for estimating hard-to-measure quantities such as volume, biomass and carbon stock in forests. However, so far there has been limited model development for native forests in Vietnam. Therefore, this study was conducted to build and analyze the effectiveness of nonlinear and mixed models for secondary and old-growth forests in Gia Lai, Vietnam. The study measured diameter at breast height, total height, commercial height and crown width of forest trees in 20 plots (10 plots for each forest stage). The results showed that diameter had the strongest relationship with height. In the secondary forest, the Power, Korf and Ratskowky models were the best for pairs of variables, while Prodan, Weibull and Power models were the best fit in the old-growth forest. The nonlinear mixed-effect models were better than classic nonlinear models in both forest stages. Fixed and mixed models developed in this study are very valuable for estimating difficult-to-measure quantities and contribute to effective forest management in the study region.
Conservation Management Model of Subayang River in the Kampar Regency, Province of Riau based on Local Wisdom using Belida Fish (Chitala sp.) as Bioindicator
Authors: Ahmad Darmadi , Sukendi Sukendi , Saam Zulfan , Suwondo
Published: April 2023

This research was conducted on the Subayang River in Kampar Regency, Riau Province, Indonesia, from January to December 2019. This research aims to determine the physical and chemical water characteristics of the Subayang River and the trend of the Belida fish (Chitalla sp.) population for constructing a river conservation management model based on local wisdom. To investigate the water's physical characteristics, a water sample was acquired from the Subayang river on three stations (upstream, middle stream, and downstream). The water sample was collected on each station iteratively at three different points at the river stream's left, middle, and right sides. The trend of Belida fish population data was gathered from interviews with the fishermen. Moreover, interviews with the traditional figure of the society around the Subayang river were also conducted. Then, the conservation model of the Subayang river was constructed by analyzing the interview and the population of Belida fish results using a system dynamic model. The investigation of the water’s physical and chemical properties shows that the Subayang river has a suitable environment for the growth of Belida fish. However, the Belida fish population trend in the last four years tends to decrease. The existence of "lubuk larangan" and "pantang larang adat", are local wisdom that gives a positive affection towards the Belida fish population. Those traditional rules can restrict citizens from doing illegal fishing which hardly affects the Belida fish population.
Seedling Recruitment of Rhododendron arboreum: an important NTFP species of North-Western Himalaya, India
Authors: Iqbal Kaiser , Negi A. K , A. Pala Dr Nazir , Todaria N.P
Published: April 2023

We examined the recruitment, survival, mortality, growth, and development of Rhododendron arboreum Smith, one of the important Non- Timber forest Product species (NTFPs). Ten permanent plots (10 x 10 m2) were created in four sites of mixed broad-leaved temperate forests of Garhwal Himalaya. We measured seedling shoot length and collar diameter at the beginning of the experiment and re-measured at three-month intervals with maximum seedling recruitment recorded in Triguginaryan (36.36 %, during Nov and Aug), and most seedlings were found established either on the boundary or in either partially or fully gaps. While a higher rate of mortality occurred in the winter season. Maximum height increment for seedlings was recorded in Adhwani (1.005 cm-1). R. arboreum recorded the highest recruitment during post-rainy, with an overall increment of 0.60 cm-1. Seasonal variations were seen in the overall relative growth rate for height (RGRH) for Rhododendron seedlings. Seasonal variation in temperature and light is a crucial factor in determining growth. Because of the favorable temperature and soil moisture during the rainy season, vigorous shoot growth continued for the longest period of time at all four sites. The current study's findings also show that seedlings develop and survive better in gaps than in the understory. The current study also demonstrates that ideal soil moisture and temperature conditions are essential for seedling growth and development.
Water Quality Assessment of Brahma Sarovar: A Sacred Lake at Kurukshetra (India)
Authors: Deswal Surinder , Dogra Sachin Kumar
Published: April 2023

Brahama Sarovar, in Kurukshetra city (India), is an ancient sacred lake where devotees perform various religious activities/offerings on daily basis, and on special occasions of solar and lunar eclipses, millions of pilgrims all over the country have mass bathing (holy-dip) for internal and external purity. Along with religious importance, this artificial lake also acts as a sacred grove/wetland that serves as an important wintering and stopover site for migratory birds from the Palearctic region. The study was carried out with the objective to analyze the improvement in water quality status after the provision of a closed conduit for the supply of fresh water to the lake and additional measures required for public health safety. For this, the water quality of this sacred lake has been spatially analyzed and compared with Indian standards prescribed for ‘Designated Best Use Class-B: Outdoor Bathing (Organised)’ in the present study. Though the parameters – pH (7.94 within the limits of 6.5-8.5), turbidity (3.63 < 5 NTU), TDS (222.33 < 500 mg/L), TSS (100.25 mg/L) and MPN (239.25 ≤ 500 per 100 ml) were observed to be within the permissible limits, but DO (4.7 ≤ 5.0 mg/L) and BOD (3.54 ≥ 3.0 mg/L) of the lake water were found beyond the permissible limits. Thus, making the lake water unfit for human use for bathing. The comparison with the previous two studies revealed that the lake’s water quality has improved in the last couple of years through the provision of a closed conduit, in place of an open channel, for the supply of fresh canal water to the lake. A couple of additional measures have also been suggested to maintain the water quality standards in the lake so as to protect the human health of the devotees and pilgrims.
Western Europe as a Model for Polish Defenders of Animal Welfare prior to 1939
Authors: Kasprzycki Remigiusz
Published: April 2023

This article looks at how Western Europe served as a model for Polish animal advocates before 1939. France and Great Britain inspired the greatest respect among Polish animal defenders. Polish animal lovers, fascinated by the French and English treatment of animals, discovered the effectiveness of grassroots initiatives, rather than legal resolutions and acts, for the welfare of animals. This article attempts to explain why the endeavour to copy the treatment of animals by wealthy Germans, French, and above all English and introduce it to economically poor Poland proved to be utopian.
Primate Stefan Wyszyński’s Pro Memoria Journal as a Historical Source
Authors: Łatka Rafał
Published: April 2023

This article is a concise analysis of the value of Primate Stefan Wyszyński’s Pro memoria as a historical source. It presents the most important facts concerning the hierarch’s journal, and proceeds to present a comprehensive discussion of the topics which Wyszyński touched upon in his notes, and of his writing style. The summary indicates fields of research which could utilize Pro memoria to their benefit, and also recapitulates the potential importance of the journal for scholarly research into the history of Poland in the years 1949–81.
Księstwo Mazowieckie u progu inkorporacji. Charakterystyka obszaru około 1526 roku (część północna)
Authors: Piber-Zbieranowska Marta
Published: April 2023

Artykuł jest drugą częścią przeglądu dziesięciu ziem Księstwa Mazowieckiego i tworzących je powiatów w przededniu włączenia ich do Królestwa Polskiego we wrześniu 1526 r. Przedstawiono w nim sześć ziem położonych w północnej i wschodniej części księstwa: wyszogrodzką, zakroczymską, ciechanowską, wiską, łomżyńską i makowsko-różańską. W sumie obszar ten obejmował czternaście powiatów. Wszystkie ziemie scharakteryzowano według jednolitego schematu, w obowiązującym ówcześnie układzie starszeństwa. Poszczególne ziemie zaprezentowano pod kątem podziałów administracyjnych (państwowych i kościelnych), procesów osadniczych i stanu sieci miejskiej, typów i rozmieszczenia własności ziemskiej oraz pozycji danej ziemi w strukturach politycznych księstwa, wyrażającej się m.in. funkcjonowaniem pełnej bądź niepełnej hierarchii urzędów oraz udziale szlachty danej ziemi w sprawowaniu władzy. Starano się pokazać zróżnicowanie stopnia zagospodarowania ziem mazowieckich i wskazać jego genezę.
Plan Kamieńca Podolskiego z 1793 roku przechowywany w Rosyjskim Państwowym Wojennym Archiwum Historycznym w Moskwie
Authors: Opyrchał Leszek , Nahnybida Rusłan , Płamienicka Olga
Published: April 2023

W artykule szczegółowo omówiono plan twierdzy Kamieniec Podolski Józefa Ekerta z 1793 r., znajdujący się w Rosyjskim Państwowym Wojennym Archiwum Historycznym w Moskwie. W celu ustalenia daty jego powstania porównano go z planami Jana Schüllera z 1773 r. oraz Dementija Mieleszczenkowa 1797 r. Wykazano, że choć plany Ekerta i Schüllera zostały wykonane na kanwie „Dużego Panu Kamieńca Podolskiego” z jedynie niewielkimi zmianami w strukturach obronnych twierdzy, to plan Ekerta przedstawia nieco wcześniejszą wersję umocnień. Plan ten umożliwia ustalenie pierwotnej, niezrealizowanej koncepcji położenia koszar kamienieckich Stanisława Zawadzkiego.
Internetowy Atlas Polski Niepodległej – metodyka opracowania bazy miejscowości i granic administracyjnych oraz analizy pochodne
Authors: Głażewski Andrzej , Kowalski Paweł J.
Published: April 2023

Artykuł przedstawia przykłady wykorzystania zasobu historycznych danych przestrzennych, zgromadzonego w ramach Internetowego Atlasu Polski Niepodległej, opublikowanego w 2021 r. jako efekt projektu Instytutu Historii PAN i Wydziału Geodezji i Kartografii Politechniki Warszawskiej. Zasadniczym celem artykułu jest ukazanie możliwości badania struktury sieci osadniczej z wykorzystaniem analiz przestrzennych oraz propozycja sposobów odtwarzania metodami kartograficznymi struktur przestrzennych: grup obiektów osadniczych czy jednostek administracyjnych.
Miasta w Atlasie historycznym Polski XVI wieku
Authors: Noga Zdzisław
Published: April 2023

Artykuł zawiera analizę zakończonej edycji ośmiu tomów Atlasu historycznego Polski. Mapy szczegółowe XVI wieku z perspektywy historii miast. Przy omawianiu map głównych i komentarzy zwrócono uwagę na kryteria kwalifikacji osiedli do kategorii miast, nie tylko prawnoustrojowe, ale również funkcjonalne. Osobne miejsce poświęcono opublikowanym planom 34 miast i komentarzom do nich. Stwierdzono zachowanie ciągłości metodologicznej i w miarę jednolitego kwestionariusza badawczego w tomach, które ukazywały się w latach 1958– 2021. Seria ukazała się też jako wydanie zbiorcze (2021) i anglojęzyczne (2014).
Jednostki organizacyjne nieposiadajace osobowości prawnej jako podatnik VAT
Authors: Kalinowski Marek , Prejs Ewa
Published: April 2023

W niniejszym artykule autorzy analizują orzecznictwo Trybunału Sprawiedliwości i odpowiadają na pytanie, jakie kryteria powinny być brane pod uwagę przy ocenie, czy określonej jednostce organizacyjnej nieposiadającej osobowości prawnej można przypisać status podatnika VAT. Jak wynika z orzecznictwa Trybunału Sprawiedliwości – zdaniem autorów – kryterium samodzielności powinno być stosowane do oceny podmiotowości podatkowej zarówno osób fizycznych i prawnych na gruncie prawa prywatnego, jak i jednostek organizacyjnych na gruncie prawa podatkowego. Przeprowadzona analiza prowadzi autorów do wniosku, że w celu ustalenia, czy dana jednostka organizacyjna posiada status podatnika VAT, należy w pierwszej kolejności zbadać, czy u tego podmiotu może wystąpić zdarzenie powodujące powstanie obowiązku podatkowego w VAT. Ponieważ zdarzenie to polega na wymianie towarów i usług w ramach stosunku prawnego, jednostka ta musi posiadać zdolność prawną do nawiązania takiego stosunku. Taką zdolność mają osoby fizyczne i prawne. Mogą ją również mieć jednostki organizacyjne nieposiadające osobowości prawnej, którym w danym systemie prawnym przyznano zdolność do nabywania praw i zaciągania zobowiązań we własnym imieniu, bez jednoczesnego przyznania im osobowości prawnej.
Prawo karne Polski „lubelskiej” (1944)
Authors: Lityński Adam
Published: April 2023

W dniu 26 lipca 1944 r. PKWN podpisał porozumienie z wodzem naczelnym Armii Czerwonej (Stalinem). Na mocy tego porozumienia władze sowieckie mogły aresztować obywateli polskich. Czyniły to masowo i wywoziły Polaków do ZSRR. Od jesieni 1944 r. komuniści w Polsce wprowadzili terror. Służył temu m.in. dekret z 30 października 1944 r. o ochronie Państwa. Dekret ten jedenaście razy przewidywał karę śmierci. Kara śmierci groziła nawet za posiadanie radia, jak również za niedoniesienie o przestępstwach przewidzianych w tym dekrecie. Denuncjacje były obowiązkowe. To wzorce sowieckie. Podobny represyjny był kodeks karny Wojska Polskiego z 23 września 1944 r.; skazywano z niego także osoby cywilne.
Dokument elektroniczny w postępowaniu cywilnym
Authors: Nowak Mariusz
Published: April 2023

Artykuł dotyczy dokumentów elektronicznych oraz problemów z nimi związanych. Dowody elektroniczne są coraz częściej wykorzystywane w sprawach cywilnych, co powinno być nadzorowane przez sędziów. Również przepisy prawne nie mogą pozostawać w tyle za rozwojem technologii i powinny być odpowiednio modyfikowane oraz dostosowywane do nowych możliwości. Skomplikowany charakter danych i informacji zapisanych w formie elektronicznej oraz wiele problematycznych kwestii związanych z wykorzystywaniem elektronicznego materiału dowodowego uzasadnia potrzebę przyjrzenia się tym zagadnieniom.
Wpływ prawomocnego wyroku orzekającego o rozwiązaniu małżeństwa przez rozwód na ważność i skuteczność rozrządzeń mortis causa na rzecz (byłego) małżonka dokonanych w czasie trwania małżeństwa
Authors: Paluch Anna
Published: April 2023

Niniejszy artykuł stanowi głos w dyskusji na temat zasadności wprowadzenia do polskiego porządku prawnego regulacji, przewidującej nieważność albo bezskuteczność nieodwołanych rozrządzeń na wypadek śmierci dokonanych na rzecz małżonka w czasie trwania małżeństwa, w wyniku późniejszego rozwiązania małżeństwa przez rozwód. Analiza tego zagadnienia została przeprowadzona w kontekście rozwiązań obowiązujących w krajach zachodnioeuropejskich, które wprost regulują tę kwestię, odwołując się do rzeczywistej bądź hipotetycznej woli testatora. W artykule zaprezentowano tezę, że nie ma podstaw, by uznawać rozrządzenia dokonane na rzecz małżonka w czasie trwania małżeństwa, które następnie ustało przez rozwód, za bezskuteczne bądź nieważne. Wola testatora manifestuje się bowiem przez brak odwołania takich rozrządzeń.
Anamnetyczny wymiar chrześcijańskich „świąt idei”
Authors: Brzeziński Daniel
Published: April 2023

Chrześcijańskie obchody w roku liturgicznym są przede wszystkim upamiętnieniem wielkich wydarzeń zbawczych, historiozbawczymi „świętami faktu”, i właśnie jako „święta pamięci” zostały wpisane w roczny cykl obchodów liturgicznych. Jednak kalendarz liturgiczny zna również obchody, które nie powstały jako doroczna pamiątka jakiegoś konkretnego wydarzenia z historii zbawienia. W literaturze historyczno- i teologicznoliturgicznej są one określane jako „święta idei” bądź „święta dogmatyczne”. Wynikają z dogmatycznej refleksji nad Objawieniem, a niekiedy także z objawień prywatnych i nurtu pobożnościowego danej epoki. W opracowaniu podjęto refleksję nad anamnetycznym wymiarem owych obchodów: czy „święta idei” są – a jeśli tak, to w jakim sensie – anamnezą Misterium Chrystusa? Tak postawione pytanie w świetle współczesnej teologii roku liturgicznego wydaje się poniekąd retoryczne, tym niemniej sam problem – wobec wielu nieporozumień, niejasności i wątpliwości – domaga się wyjaśnienia i doprecyzowania.
Knowledge Of Legal Liability In Sports Among Sports Council Personnel In South-South, Nigeria.
Authors: Alaubi Stanley C. , Nwankwo G. O.
Published: April 2023

A study on knowledge of legal liability in sports, among male athletes in sport councils in South-South Nigeria. Nine research questions and six null hypotheses were tested at 0.05 alpha levels. The population for this study comprised of all the 3,321 athletes and coaches in south south Nigeria with a sample size of 645 respondents (140 coaches and 505 athletes).  The study adopted the cross sectional survey design. The sampling technique used was multi stage sampling procedure. The research instrument was subject to both face and content validation by the researcher’s supervisor and two experts in the field of measurement and evaluation. The reliability coefficient of 0.78 was obtained using the Pearson Product Moment Correlation statistical analysis. The collected data were analyzed using frequency, percentage, mean and standard deviation for the research questions, while multiple regression were used for the testing of the null hypotheses at 0.05 alpha level of significance. The findings established that: 401 (62.2%) Sport personnel in South-South Nigeria possessed good knowledge of legal liability in sports while 244 (37.8%) do not. Based on these findings, it was recommended among others that: Ministry of sport should introduce sporting activities, training and retraining from time to time in order to improve the knowledge of Sports personnel with issues relating to legal liability in sport.
From noun to future tense
Authors: Fries Simon , Halfmann Jakob , Hill Eugen , Hübner Denise
Published: April 2023

This article explores a typologically unusual but recurrent evolutionary path of innovated future formations neglected by typological research: the change of predicative deverbal nouns (understood here in the broad sense of any deverbal nominal expression/formation) – namely agent nouns and participles – denoting actions typical of referents to future verb-forms via hypoanalysis. Starting with an overview of typologically recurrent ways of creating new future formations, the article seeks to demonstrate that the l-future found in the three Nuristani languages Nuristani Kalasha, Ashkun and Katë developed from active participles designating actions typical of their referents. As a typological parallel of this development the Vedic Sanskrit tā́-future is established, and it is shown by the example of the English will + infinitive future and the futurate use of Russian perfective non-past verb-forms how the change of predicative deverbal nouns denoting actions typical of referents to future verb-forms is brought about by means of hypoanalysis.
Cognitive Reappraisal Impairs Negative Affect Regulation in the Context of Social Rejection for Youth With Early-Stage Borderline Personality Disorder
Authors: Pizarro-Campagna Elizabeth , Terrett Gill , Jovev Martina , Rendell Peter G. , Henry Julie D. , Chanen Andrew M.
Published: April 2023

Application of emotion regulation strategies might be susceptible to the context of social rejection for individuals with borderline personality disorder (BPD). This study compared the ability of 27 outpatient youths (15-25 years old) with early-stage BPD and 37 healthy controls (HC) to apply expressive suppression and cognitive reappraisal in standard and socially rejecting laboratory contexts. BPD youths were largely as able as HCs to regulate negative affect across instruction and contexts. However, cognitive reappraisal in the context of social rejection heightened BPD negative facial expression relative to HCs. Thus, while BPD emotion regulation ability was largely normative, cognitive reappraisal might be ineffective in the context of social rejection for this group, with social rejection acting as an accelerant that heightens the expression of negative affect. Given the common experience of perceived and actual social rejection for this group, clinicians should carefully consider treatments that include cognitive reappraisal strategies because they might be contraindicated.
Cognitive Processes Underlying the Weapon Identification Task: A Comparison of Models Accounting for Both Response Frequencies and Response Times
Authors: Laukenmann Ruben , Erdfelder Edgar , Heck Daniel W. , Moshagen Morten
Published: April 2023

The weapon identification task (WIT) is a sequential priming paradigm designed to assess effects of racial priming on visual discrimination between weapons (guns) and innocuous objects (tools). We compare four process models that differ in their assumptions on the nature and interplay of cognitive processes underlying prime-related weapon-bias effects in the WIT. All four models are variants of the process dissociation procedure, a widely used measurement model to disentangle effects of controlled and automatic processes. We formalized these models as response time-extended multinomial processing tree models and applied them to eight data sets. Overall, the default interventionist model (DIM) and the preemptive conflict-resolution model (PCRM) provided good model fit. Both assume fast automatic and slow controlled process routes. Additional comparisons favored the former model. In line with the DIM, we thus conclude that automatically evoked stereotype associations interfere with correct object identification from the outset of each WIT trial.
Barre-fitness as a modern means of improving the health of women in the first period of adulthood
Authors: Inna Krasova  , Alla Semyzorova  , Alfiia Deineko  , Ihor Beihul  , Olena Shyshkina
Published: April 2023

Purpose: to determine the effect of Barre-fitness classes on the morphofunctional state and physical fitness of women in the first period of adulthood.

Material & Methods: the results of a study of 35 women of the first period of adulthood (21–35 years old) with fitness experience from 6 to 12 months are presented. The female participants, taking into account the age and results of the initial study, were divided into 2 groups: the main group (MG), (n=18) and the control group (CG), (n=17). The women of the control group were engaged in dance fitness, and the women of the main group were engaged in specially designed Barre-fitness exercises. To achieve the set goals, physical development was assessed using anthropometric indicators: body length and weight; waist circumference, hip circumference. To assess the functional capabilities of women, the indicators of the cardiovascular and respiratory systems were studied.

Results: during the study, a statistically significant (p<0.05–0.01) improvement was observed in most of the studied morpho-functional parameters of women in the MG, with the exception of hip circumference, systolic blood pressure and diastolic blood pressure (p>0,05). The indicators of women in the CG also had a positive trend, but did not reach statistically significant differences (p>0,05). As a result of the use of Barre-fitness means, there was a significant statistically significant (p<0,05-0,001) improvement in the results of the physical fitness of women in the MG, with the exception of the “Shuttle run 4×9 m” indicator (p>0,05). The indicators of women in the CG also had a positive trend, but did not reach statistically significant differences (p>0,05).

Conclusions: the conducted study testifies to the positive impact of Barre-fitness classes on the morphofunctional state, the level of physical fitness and the health of women in the first period of adulthood. The obtained results make it possible to recommend Barre-fitness means for training women in fitness clubs and studios, as well as in the educational process of future specialists in physical culture and sports in higher education institutions.
Applicational study on the edible university landscape under COVID-19 epidemic circumstance
Authors: Zhou Junce , Sun Taoze , Guo Xiaohua , Wang Wei , Mu Hongna
Published: April 2023

All of universities or colleges have to solve the big challenges from the outbreak of COVID-19. Quarantining of Campus has been being the regular management policy, the activities of all students were restricted inside the campus. Under such status, campus landscape quality. In this study, the concept of Edible Landscape has been introduced into the campus planning and designing. The construction principles of healing, practicality, ecology, economy and adaptation to local conditions were illustrated, in the light of COVID-19 controlling and prevention. Furthermore, a construction strategy of edible landscape in assisting related teaching and researching activities, taking away negative emotions, and producing fresh and delicious fruits and vegetables, which can offset the shortcoming of traditional landscape of ornamental-value-centered. The construction principles and strategies of this paper put forward novel thinking and references to carry out the construction and development of campus landscape with ecology, healthy and effective traits, to the application of edible and pluralistic school landscape.