bluuebunny/crossref_metadata_2025 huggingface dataset:
Chapitre 2. Le droit des risques psychosociaux et la distanciation physique au travail
Authors: Russo Sandra
Published: March 2023

Le Covid 19 a produit un renouvellement des conditions de travail susceptible d’affecter la santé mentale, un risque professionnel que le droit des risques psychosociaux (RPS) contribue à prévenir. L’article met en lien le stress, un des composants de ce droit en formation, et le télétravail, solution de mise à distance des corps physiques. Pour constituer un RPS, le stress doit être pathogène. Une question essentielle se pose : comment l’éviter ? Dans le prolongement, d’une part, des divers fondements du droit des RPS applicables au télétravail, il s’agit, d’autre part, d’apprécier les outils dont disposent les acteurs tenus de veiller à la prévention. Bien que le droit des RPS ne cesse d’évoluer vers plus de sécurité pour la santé mentale, quelques pistes sont proposées pour le cas particulier des télétravailleurs.
Chapitre 6. Identité physique et identité numérique à l’ère de la distanciation sociale
Authors: Mattiussi Julie
Published: March 2023

La « distanciation sociale » de la crise Covid-19 a mis sur le devant de la scène un phénomène à l’œuvre depuis l’essor du Web : les personnes échangent des biens et des services, s’expriment et se rencontrent de plus en plus sans être présentes physiquement ; les corps disparaissent derrière les écrans. Émerge alors la question de l’identité numérique. Quelle place occupe-t-on sur les réseaux ? Quel contrôle les personnes exercent-elles sur leur image ? Quelle place occupent les écrits dans la définition de cette « image » numérique de soi ? Quelle appréhension de la pluralité des identités qu’une même personne peut avoir en ligne ? Le présent article propose une réflexion sur ces différentes questions en distinguant les identités numériques avec et sans personnes physiques.
L’Amérique dans l’Indo-Pacifique
Authors: Pant Harsh V. , Singh Mann Anant , Briex Gabriel
Published: March 2023

Les dirigeants américains – de Barack Obama à Joe Biden, en passant par Donald Trump – accordent une importance primordiale à l’Indo-Pacifique. Cette vaste région est vue comme le cœur de la géopolitique mondiale du xxi e  siècle. Il s’agit non seulement d’y faire face aux ambitions de la Chine, mais également de développer les relations avec des acteurs de poids comme l’Inde ou le Japon. Le « pivot » des États-Unis vers l’Indo-Pacifique ne sera pas remis en cause par la guerre en Ukraine.
Un an de guerre en Ukraine : où en sont les Russes ?
Authors: Kastouéva-Jean Tatiana
Published: March 2023

La population russe, abreuvée par la propagande du Kremlin depuis des années, approuve très majoritairement la guerre en Ukraine. Les voix critiques ou dissidentes existent, mais elles s’expriment d’autant moins publiquement que la contestation est passible de lourdes peines. Face au raidissement du régime, beaucoup d’opposants et d’hommes hostiles à la mobilisation ont quitté la Russie. Ils sont considérés comme des traîtres dans leur pays, mais ne sont pas toujours bien accueillis ailleurs.
Pakistan : la double crise politique
Authors: Chaudet Didier
Published: March 2023

Le Pakistan est confronté à une double crise politique, sur fond de situation économique catastrophique et de regain des violences. À Islamabad, le Premier ministre déchu Imran Khan crie au complot ourdi de l’extérieur et ambitionne de reprendre le pouvoir à son successeur, Shehbaz Sharif. Dans les provinces périphériques, les tensions s’aiguisent au Baloutchistan et dans le Khyber Pakhtunkhwa. En 2023 auront lieu des élections générales : l’année s’annonce lourde de périls.
MSGraph: Modeling multi-scale K-line sequences with graph attention network for profitable indices recommendation
Authors: Wang Changhai , Ren Jiaxi , Liang Hui
Published: March 2023

Indices recommendation is a long-standing topic in stock market investment. Predicting the future trends of indices and ranking them based on the prediction results is the main scheme for indices recommendation. How to improve the forecasting performance is the central issue of this study. Inspired by the widely used trend-following investing strategy in financial investment, the indices' future trends are related to not only the nearby transaction data but also the long-term historical data. This article proposes the MSGraph, which tries to improve the index ranking performance by modeling the correlations of short and long-term historical embeddings with the graph attention network. The original minute-level transaction data is first synthesized into a series of K-line sequences with varying time scales. Each K-line sequence is input into a long short-term memory network (LSTM) to get the sequence embedding. Then, the embeddings for all indices with the same scale are fed into a graph convolutional network to achieve index aggregation. All the aggregated embeddings for the same index are input into a graph attention network to fuse the scale interactions. Finally, a fully connected network produces the index return ratio for the next day, and the recommended indices are obtained through ranking. In total, 60 indices in the Chinese stock market are selected as experimental data. The mean reciprocal rank, precision, accuracy and investment return ratio are used as evaluation metrics. The comparison results show that our method achieves state-of-the-art results in all evaluation metrics, and the ablation study also demonstrates that the combination of multiple scale K-lines facilitates the indices recommendation.
The role of the Italic community as a new agent of glocal development in the post-pandemic era
Authors: Terranova Giuseppe
Published: March 2023

The pandemic and the digital revolution are changing the global geopolitical landscape. The dispersion of power linked to the new digital decision-making centers is accompanied by a fragmentation of the traditional system of power in the international geopolitical arena. In this scenario, it is difficult to identify who is in charge of sovereignty and governance. A glocal perspective would suggest continuing to look at States, but also at local political entities, such as cities, and super-national cultural identities, such as global civilizations. It is a solution that could allow Italy, and other countries, to avoid what John Agnew called the territorial trap that would push the world system into giving national answers to the growing number of global challenges. In the post-pandemic phase, Italy will face its most important test of resilience since the Second World War. This paper intends to investigate whether and in what terms the Italian State will be able to recognize and make use of the soft power of the Italic community and civilization as a new agent of glocal development. The digital revolution accelerated by the pandemic could in fact transform the digital space into the ideal place for the recognition and strengthening of the global network of Italics around the world. Italic is not simply a synonym for Italian. Italic is someone who appreciates and recognizes the charm of Italy. The Italic does not necessarily have a passport or an Italian bloodline; he can live in Italy or anywhere else. The way of life and the commonality of values is the glue that unites Italics and this can become a soft power of Italy, strengthening the Italian State internally and externally. We refer to that mix of culture, taste, style, quality craftsmanship, fashion, design, high-value manufacturing, electronics, robotics, avant-garde entrepreneurship and gastronomic excellence that gives life to a refined art of living well.
La maison du langage. Questions de sociolinguistique et de psychologie du langage
Authors: Varro Gabrielle
Published: March 2023

Resoconto di una raccolta d’articoli in cui ATK si riferisce ai pensatori del passato, tramite i loro scritti e la sua lettura personale. Né i secoli, né la morte possono interrompere del tutto queste interazioni, scrive Andrée, e il linguaggio come legame sociale conserva tutto il suo significato.
Research Philosophy
Authors: Saliya Candauda Arachchige
Published: March 2023

The purpose of this chapter is to summarize the philosophical developments in the academic research field and provide a framework for non-native English-speaking budding researchers. Revealing the philosophical stance of the authors of a research paper is crucial in understanding their arguments. Therefore, an understanding of this historical evolution is useful in justifying authors' choices and presenting them clearly in the research report. Authors' perceptions of different theories, perspectives, and worldviews influence and affect many aspects of research, and it is important to mention personal stances on them in the research report at the very beginning. The choice of underpinning philosophy is significantly influenced by the author's psychosocial, economic, and cultural backgrounds. Multivism is a dynamic position of a researcher who is not confined to the bipolar-disordered extremism of objectivism and subjectivism of ontology, epistemology, methodology, and methods.
The Acceptable R-Square in Empirical Modelling for Social Science Research
Authors: Ozili Peterson K.
Published: March 2023

This chapter examines the acceptable R-square in social science empirical modelling with particular focus on why a low R-square model is acceptable in empirical social science research. The paper shows that a low R-square model is not necessarily bad. This is because the goal of most social science research modelling is not to predict human behaviour. Rather, the goal is often to assess whether specific predictors or explanatory variables have a significant effect on the dependent variable. Therefore, a low R-square of at least 0.1 (or 10 percent) is acceptable on the condition that some or most of the predictors or explanatory variables are statistically significant. If this condition is not met, the low R-square model cannot be accepted. A high R-square model is also acceptable provided that there is no spurious causation in the model and there is no multi-collinearity among the explanatory variables.
Estimating Latent Growth Curve Models
Authors: Wickrama K. A. S.
Published: March 2023

Although LGC modeling is gaining popularity in some disciplines, it has not been widely employed in social-epidemiological studies. This paper presents an introduction to the latent growth curve (LGC) technique within a structural equation modelling (SEM) framework as a powerful tool to analyze change in individual attributes over time (e.g., behaviors, attitudes, beliefs, and health) and potential correlates of such changes. The rationale for LGC analysis and subsequent elaboration of this statistical approach are discussed. For illustrations, Mplus (version 8, Muthén & Muthén, 2012) software and depressive symptoms as the individual outcomes attribute are used. The limitations of traditional analytical methods are also addressed. Particularly, the chapter considers socio-contextual factors as correlates of change in the outcomes variable, and examines the dynamic systematic relationship with the socioeconomic factors (however, these correlates can also be factors other than social-context).
A New Feature Selection Method Based on Dragonfly Algorithm for Android Malware Detection Using Machine Learning Techniques
Authors: Guendouz Mohamed , Amine Abdelmalek
Published: March 2023

Android is the most popular mobile OS; it has the highest market share worldwide on mobile devices. Due to its popularity and large availability among smartphone users from all around the world, it becomes the first target for cyber criminals who take advantage of its open-source nature to distribute malware through applications in order to steal sensitive data. To cope with this serious problem, many researchers have proposed different methods to detect malicious applications. Machine learning techniques are widely being used for malware detection. In this paper, the authors proposed a new method of feature selection based on the dragonfly algorithm, named BDA-FS, to improve the performance of Android malware detection. Different feature subsets selected by the application of this proposed method in combination with machine learning were used to build the classification model. Experimental results show that incorporating dragonfly algorithm into Android malware detection performed better classification accuracy with few features compared to machine learning without feature selection.
Understanding the Determinants of Customer Intention to Use Mobile Payment
Authors: Changchit Chuleeporn , Changchit Charles , Cutshall Robert , Pham Long , Rao Mohan
Published: March 2023

Previous studies on the intention to use mobile payment were mainly conducted using traditional technology acceptance models, which focus on positive factors and ignore negative factors influencing the intention to use mobile payment in both developed and developing countries. This study is conducted in a newly emerging country, Vietnam – a trusted destination for multinational companies to do business and reposition their global supply chains. With the integration of positive and negative factors into an extended research model to examine their influence on the intention to use mobile payment, the results show that perceived privacy and perceived security contribute to overall perceived risk. Moreover, perceived risk and perceived compatibility are two determinants of intention to use mobile payment. Theoretical and managerial implications are drawn and directions for future research are outlined.
Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape
Authors: Zhao Yingze , Xiao Wenling , Wu Yanan , Fan Wenhui , Li Lei , Yue Can , Zhang Qingxu , Zhang Danni , Yuan Xiaoju , Yao Sijia , Liu Sai , Li Min , Wang Pengyan , Zhang Hangjie , Zhang Jie , Zhao Min , Zheng Xiaoqun , Liu Wenjun , Gao George F , Liu William J
Published: March 2023

Influenza A viruses (IAVs) and influenza B viruses (IBVs) cause annual epidemics in human populations with seasonal circulation spikes. Peptide AM58–66GL9 located at residues 58–66 of M1 protein of IAVs has been recognized as an immunodominant T cell epitope with HLA-A*0201 restriction and broadly used as a positive reference in influenza immunity. This peptide also almost completely overlaps with a nuclear export signal (NES) 59–68 in IAV M1, which explains the limited escape mutations under the T cell immune pressure in this region. In this study, we investigated the potential immunogenicity and NES in the corresponding region of IBV. The long peptide covering this region can be recognized by specific T cells and induce robust expression of IFN-γ among HLA-B*1501 donors in vivo, but not in HLA-A*0201 donors. Among a series of truncated peptides derived from this region, we identified an immunodominant HLA-B*1501–restricted T cell epitope BM58–66AF9 (ALIGASICF) in the M1 protein of IBV. Furthermore, the structure of the HLA-B*1501/BM58–66AF9 complex shows that BM58–66AF9 performs a flat and featureless conformation that is similar to AM58–66GL9 presented by HLA-A*0201. In contrast with IAV, the sequence around residues 55–70 of IBV M1 does not contain an NES. Our comparative study on IBVs and IAVs provides new insights into the immune and evolution characteristics of IBVs and may shed light on vaccine development for influenza viruses.
Anti-tumor Efficacy of a Bevacizumab Preconditioning followed by Etoposide and Cisplatin Regimen in Human Epidermal Growth Factor Receptor-2-Positive Breast Cancer Brain Metastasis Refractory to Whole Brain Radiotherapy
Authors: Chen Tom Wei-Wu , Lin Ching-Hung , Yeh Dah-Cherng , Tseng Ling-Ming , Rau Kun-Ming , Chen Bang-Bin , Chao Ta-Chung , Huang Shu-Min , Chang Dwan-Ying , Chen I-Chun , Cheng Ann-Lii , Lu Yen-Shen
Published: March 2023

Background:

For human epidermal growth factor receptor-2 (HER2)-positive metastatic breast cancer (MBC), treating brain metastasis (BM) remains challenging. We have previously demonstrated that administering bevacizumab 1 day before etoposide and cisplatin (BEEP) can significantly improve antitumor efficacy in cases of breast cancer with BM. Herein, we report the antimetastatic brain tumor efficacy of BEEP in an HER2-positive subpopulation.

Materials and Methods:

Thirty-five MBC patients with BM were enrolled from January 2011 to January 2013. BEEP was given in 21 day cycles: bevacizumab 15 mg/kg on day 1, etoposide 70 mg/m2/day from days 2 to 4, and cisplatin 70 mg/m2 on day 2. The primary endpoint was composite central nervous system (CNS) volumetric objective response rate (ORR). Anti-HER2 treatments were not permitted during the clinical trial.

Results:

A total of 23 patients were HER2-positive, 9 ER-positive, and 14 ER-negative. All had been exposed to trastuzumab; 11 (47.8%) had received lapatinib treatment, and 6 (26.1%) of them had received both lapatinib and capecitabine treatment. Of these, 16 patients (69.6%, 95% confidence interval [CI] 47.1–86.8) achieved CNS-ORR, including 7 (30.4%) with ≥80% and 9 (39.1%) with 50%–80% CNS volumetric reduction. A further 5 patients (21.7%) had 20%–50% CNS volumetric reduction. Median CNS-specific progression-free survival and overall survival were 7.4 (95% CI 5.8–9.0) and 11.8 (95% CI 8.7–14.9) months, respectively. Toxicities were tolerated with granulocyte-colony stimulating factor support.

Conclusion:

The BEEP regimen had a significant antitumor effect in cases of BM of HER2-positive breast cancer that progressed following whole brain radiotherapy.
Perioperative Anaesthetic challenges during the management of Mucormycosis in a recovered SARS-CoV-2 Patient
Authors: Ahmad Sarfaraz , Kumar Neeraj , Kumar Amarjit , Rathinasamy Mithun
Published: March 2023

Mucormycosis is a progressive, opportunistic fungal infection with high risk of mortality. Rampant use of steroids in the treatment coronavirus disease 2019 creates a fertile environment for mucor growth. Perioperative challenges for the anesthesiologist in a patient having post-coronavirus disease mucormycosis include increased risks of arterial and venous thromboembolism, poor glycemic control and myocardial dysfunction, adrenal insufficiency from corticosteroid use, pulmonary dysfunction, and residual neuromuscular weakness. So, a complete biochemical workup of renal functions, hypothalamic–pituitary–adrenal axis, electrolyte, coagulation profile, optimization of blood glucose, and pulmonary function should be done.
Comparative study of tocilizumab versus itolizumab in coronavirus disease 2019-infected patients
Authors: Poonam Kumari , Chandni Sinha , Amarjeet Kumar , Ajeet Kumar , Shettru K. Arun , Pavan K. Kandrakonda
Published: March 2023

Objective

We aimed to compare the effect of tocilizumab and itolizumab in terms of PaO2/FiO2 ratio (P/F ratio), interleukin 6 (IL-6) level, serum ferritin, C-reactive protein, and a reduction in mortality. Our primary objective was to compare P/F ratio at various time intervals: baseline (before administering the drug), 12 h after drug administration, once a day for the next 7 days, and on the 14th day. Our secondary objective was to evaluate serum level of biomarkers like IL-6, ferritin, and C-reactive protein before start of drug infusion and following drug infusion at 72 h and on 7th day.

Patients and methods

A total of 50 patients, age between 18 and 60 years, having moderate Acute Respiratory distress syndrome (ARDS) following coronavirus disease 2019 infection were recruited. Patients of group I received a single dose of injection of tocilizumab 8 mg/kg intravenously (i.v.) via infusion over 1–2 h. Group II patients received premedication with hydrocortisone 100 mg and pheniramine 30 mg and a single dose of injection itolizumab 1.6 mg/kg dissolved in 250 ml of 0.9% normal saline infusion over 5–6 h.

Results

We observed significantly higher P/F ratio in the itolizumab group (239.18±97.31) than in the tocilizumab group (104.87±75.25) on the 3rd day following drug administration (P<0.001). Similarly, the IL-6 level was lower in the itolizumab group (72±100) in comparison with the tocilizumab group (682±1360), and the differences were statistically significant (P<0.05). We identified adverse effects of the drugs in 10 patients who have received itolizumab.

Conclusion

We observed an increasing trend in P/F ratio on the 3rd day following itolizumab administration in comparison with tocilizumab, and the difference was statistically significant (P<0.001).
Serum interleukin-6 as a predictor of the severity of coronavirus disease 2019
Authors: Ahmed Islam M. , Hefny Hesham M. , Ali Amal H. , Refaie Bahaa M. , Abdelal Khalid M. , Taha Elhaisam M.
Published: March 2023

Background

Inflammatory markers like interleukin-6 (IL-6) are linked to the worse outcome in coronavirus disease 2019 (COVID-19) cases. Other markers such as C-reactive protein are not as reliable as IL-6 in predicting respiratory failure.

Aim

To assess the function of IL-6 as a predictor of COVID-19 severity.

Patients and methods

A total of 50 severe and critical patients with PCR-confirmed COVID-19 were included. All enrolled patients followed the case definition for confirmed cases of Egyptian national protocol for COVID-19 issued by MOHP. Clinical assessment, imaging, and laboratory data were recorded at admission. Pulmonary function was evaluated by SpO2/FiO2 ratio. Outcomes included hospital stay, prognosis of the disease, complications, death rate, and discharge, which were recorded during the follow-up.

Results

The elevated IL-6 group showed a significantly higher critical rate (87.1%) than the normal IL-6 group (26.3%) (P<0.0001), and the improvement rate was higher in the normal IL-6 group (73.7%). Moreover, the death rate was significantly greater in the elevated IL-6 group (38.7%) than the normal IL-6 group (10.5%) (P=0.033). The cutoff value of IL-6 levels in prediction of severity and mortality of COVID-19 was assessed. Our receiver operating characteristic results revealed that IL-6 cutoff value is higher than 50.27 for severity and the cutoff value is greater than 120.83 for mortality. The sensitivity values of IL-6 for severity and mortality were 93.3 and 90.5%, respectively, and the specificity values were 90.0 and 86.7%, respectively.

Conclusion

Elevated levels of serum IL-6 in COVID-19-infected patients were related with a variety of adverse outcomes, including severe illness, mechanical ventilation, and acute respiratory distress syndrome. When it came to accurately predicting the severity and mortality of COVID-19, the optimum IL-6 cutoff levels were 50.27 and 120.83 pg/ml, respectively.
Renal resistive index as a predictor of hemodialysis and mortality risk in septic patients developing acute kidney injury
Authors: Nour Islam A. , Eldehily Khalaf I. , Abd Elbaset Ahmed S. , Saber Hamdy M.
Published: March 2023

Introduction

Mechanisms of acute kidney injury (AKI) comprise renal hypoperfusion, intrarenal vasoconstriction, inflammation, oxidative stress, and nephrotoxicity. An important pathophysiological pathway includes intrarenal vasoconstriction and endothelial damage of the microvessel, leading to impaired macrovascular and microvascular flow, which further aggravates ischemia. Nowadays, Doppler ultrasound is rapidly gaining ground as a screening tool in critically ill patients. The performance of cardiac, lung, and abdominal ultrasound in patients after cardiac arrest, major operations, and during shock has become the standard policy. However, renal ultrasound, which could be easily incorporated in this screening, is not commonly performed.

Aim

To test the ability of renal resistive index (RRI) measurement by Doppler ultrasound to predict the development of AKI in septic patients and find a relation with the progression to persistent renal impairment and relation to outcome and mortality.

Patients and methods

A total of 40 septic patients with AKI were randomized and subjected to RRI measurements, on admission and after 48 h, and the patients were followed till hospital discharge to detect the correlation to outcome. Mortality risk assessment was measured by the APACHE III score.

Results

There was a statistically significant increase of RRI in cases with persistent AKI in comparison with cases with transient AKI (P<0.05). There was a statistically significant increase in APACHE III score in patients with high RI (P<0.005).

Conclusion

Renal Doppler RI may be a promising tool for predicting the risk of developing AKI in acutely ill septic patients and may help in predicting the reversibility of AKI. High RRI values in septic patients with AKI are independently related to ICU mortality and persistent renal dysfunction at discharge from ICU.
Comparative study lumbar plexus block and lumbar erector spinae plane block for postoperative pain relief after proximal femoral nail for proximal femoral fractures
Authors: Diwan Sandeep , Lonikar Abhishek , Dongre Himaunshu , Sancheti Parag , Nair Abhijit S. , Panchawagh Suhrud
Published: March 2023

Background:

The clinical outcomes (time to ambulation, length of stay, and home discharge) after proximal femoral nail (PFN) for proximal femoral fractures (PFF) is dependent on successful pain management. Currently, the lumbar erector spinae plane block (LESPB) is in vogue and is associated with favorable outcomes in the postoperative period. Our study aimed to evaluate whether a LESPB provided equivalent analgesia and clinical outcomes as compared to LPB in PFN for PFF.

Material and Methods:

We compared LPBs [L] with LESPBs [E], with 30 patients in each group, performed from June 2020 to June 2021 for PFN in PFF's. The primary outcome of this study was the average NRS pain scores over 24 hours postoperatively. Secondary outcomes included pain scores at different time points over 24 hours, opioid consumption between the groups at 24 hours postoperatively, time for request of first parenteral analgesia, quadriceps weakness and adverse events.

Results:

The average pain scores over 24 hours were better in the LESPB group as compared to the LPB group (p = 0.02). Further, only n = 5 (30%) of patients in the LESPB group required opioids, while n = 13 (43.333%) of patients in the LPB group required opioids. Moreover, the median time for request of first parenteral analgesia was 615 (480–975) minutes, weakness of quadriceps function occurred in 2 patients in the L group, which recovered at 3rd and 5th month, respectively, with no incidences of hemodynamic instability and respiratory complications.

Conclusions:

This trial demonstrated that single bolus LESPB is superior to LPB in terms of analgesic outcomes, has low adverse events, and is an agreeable substitute for patients with PFF undergoing a PFN.
Anesthetic challenges for pheochromocytoma surgery in pediatric patients
Authors: Vyas Raksha , Sharma Ankur , Goyal Shilpa , Vyas Varuna , Kothari Nikhil
Published: March 2023

Pheochromocytoma in children is an exceptionally uncommon cause of hypertension in this age group. These tumors pose a significant threat of adverse cardiovascular events during the perioperative phase. In this article, we describe three cases of pediatric pheochromocytoma to shed light on the difficulties associated with administering anesthesia to patients with this condition. The foundations for successful perioperative outcomes include preoperative blood pressure control, extensive intraoperative hemodynamic evaluation, and appropriate coordination with surgeons.
Radial artery duplication
Authors: Mohanty Chitta Ranjan , Radhakrishnan Rakesh Vadakkethil , Das Subhasree , Tripathy Prabhas Ranjan , Behera Shri Hari Priya
Published: March 2023

The radial artery is the most common choice for arterial cannulation, coronary interventions, and various interventional radiological procedures. Here, we describe a case of unilateral duplication of the radial artery detected during radial artery cannulation using point-of-care ultrasonography (POCUS). The duplication of the radial artery in the forearm can hinder trans-radial access secondary to variations in the diameter. An actual duplication also carries a high risk of accidental injury to the arterial wall during routine invasive procedures and other forearm procedures such as free flap construction. POCUS is invaluable for detecting arterial anomalies before proceeding with any interventional procedures.
Anesthetic management of a young primigravida a case of symptomatic long QT syndrome with a permanent pacemaker in-situ undergoing lower segment cesarean section delivery
Authors: Pegu Baby , Singh Ram
Published: March 2023

The patient with Long QT syndrome (LQTS) presents a unique challenge to the anesthesiologist. The anesthetic management of such patients requires a good knowledge of the pathophysiology of this rare disease. General anesthesia (GA) or combined spinal epidural anesthesia (CSEA) are the most preferred anesthetic techniques among anesthesiologists for such patients posted for the lower segment cesarean section delivery. In this report, we would like to share our experience of anesthetic management of a young primigravida, a case of symptomatic LQTS with a permanent pacemaker in situ. Anesthetic technique used for the lower segment cesarean section delivery was single-shot spinal anesthesia using a combination of a local anesthetic and strong opioid in the lumber subarachnoid space. Until recently, only one report in the literature has described this single-shot spinal technique for such cases. The advantages of single shot spinal over GA and CSEA can be utilized in a select group of these patients, which include fast onset, dense, reliable block with low local anesthetic toxicity, reduced catecholamine release, and relatively prolonged analgesia when combined with an opioid.
Streptococcus suis meningitis in a COVID-19 patient
Authors: Viana Patrícia Bastos , Penedos Constança , Medeiros Rita , Monte Raquel
Published: March 2023

Streptococcus suis is a Gram-positive, facultative anaerobic bacterium and has its natural reservoir in pigs. Infection by this microorganism usually manifests in humans as meningitis, endocarditis, sepsis, and/or arthritis after contact with pigs or pork. Meningitis is a very common manifestation and Streptococcus suis may be considered its second most common cause. A clinical course may manifest acutely or with a more chronic course. Streptococcus suis is endemic in pork-consuming and pig-rearing countries, but may occur all over the world, especially in individuals with occupational exposure to pigs and/or pork, such as abattoir workers, butchers, and farmers. Most infections are observed in adults without preexisting diseases. We report a case of Streptococcus suis meningitis in a healthy patient with occupational exposure and with an asymptomatic infection by severe acute respiratory syndrome coronavirus 2, who was admitted to an intensive care unit in a tertiary hospital in the North of Portugal.
Anesthetic management of deep brain stimulation in Hallervorden–Spatz syndrome
Authors: Monteiro Joseph Nascimento , Bedekar Unmesh Pramod
Published: March 2023

Anesthetic management of dystonic patients with uncontrolled involuntary movements refractory to medical management is a challenge to neuroanaesthetists. According to some studies, the prevalence of Panthothenate Kinase Associated Neurodegeneration is 1 to 9/1,000,000. Report of Deep Brain Stimulation for Hallervorden–Spatz is extremely rare in literature. “Awake” bilateral electrode placement, with microelectrode recording (MER) and stimulation with a scalp nerve block, titrated conscious sedation with Monitored Anesthesia Care (MAC) is preferable. However, in those patients needing general anesthesia, a balanced anesthesia technique with careful selection and monitored titration of anesthetic drugs ensuring MERs for precise placement and stimulation of target nuclei along with adequate plane and depth of anesthesia and prevention of awareness are essentially the key factors in the anesthetic management. Surgery is the mainstay of the disease due to poor response to medical management. Multidisciplinary collaboration and cooperation among neurologists, neurosurgeons, neuroradiologists, and neuroanaesthesiologists are imperative to ensure good patient outcomes.
Sedation for adult ICU patients
Authors: De Bels David , Bousbiat Ibrahim , Perriens Emily , Blackman Sydney , Honoré Patrick M
Published: March 2023

The optimization of patients’ treatment in the intensive care unit (ICU) needs a lot of information and literature analysis. Many changes have been made in the last years to help evaluate sedated patients by scores to help take care of them. Patients were completely sedated and had continuous intravenous analgesia and neuromuscular blockades. These three drug classes were the main drugs used for intubated patients in the ICU. During these last 20 years, ICU management went from fully sedated to awake, calm, and nonagitated patients, using less sedatives and choosing other drugs to decrease the risks of delirium during or after the ICU stay. Thus, the usefulness of these three drug classes has been challenged. The analgesic drugs used were primarily opioids but the use of other drugs instead is increasing to lessen or wean the use of opioids. In severe acute respiratory distress syndrome patients, neuromuscular blocking agents have been used frequently to block spontaneous respiration for 48 hours or more; however, this has recently been abolished. Optimizing a patient's comfort during hemodynamic or respiratory extracorporeal support is essential to reduce toxicity and secondary complications.
Free pre-Lie family algebras
Authors: Zhang Yuanyuan , Manchon Dominique
Published: March 2023

In this paper, we first define the pre-Lie family algebra associated to a dendriform family algebra in the case of a commutative semigroup. Then we construct a pre-Lie family algebra via typed decorated rooted trees, and we prove the freeness of this pre-Lie family algebra. We also construct pre-Lie family operad in terms of typed labeled rooted trees, and we obtain that the operad of pre-Lie family algebras is isomorphic to the operad of typed labeled rooted trees, which generalizes the result of Chapoton and Livernet. In the end, we construct Zinbiel and pre-Poisson family algebras and generalize results of Aguiar.
Graph Theory
Authors: Geelen Jim , Král' Daniel , Scott Alexander
Published: March 2023

Graph theory is a quickly developing area of mathematics, with an increasing number of connections to various parts of mathematics and computer science. The workshop aimed at bringing together a broad range of researchers at various career stages to discuss recent exciting developments, in particular, the Product Structure Theorem and progress towards the resolution of Hadwiger’s Conjecture. While the workshop was impacted by the COVID pandemic, it still offered many interesting talks, which updated its participants on recent developments covering the whole breadth of graph theory, and collaboration opportunities.
On-Line Pose Measurement and Adjustment of End Effector Based on
Laser Tracker for Robotic Drilling System
Authors: Tang Yue , Zheng Jinhui , Zhang Mao
Published: March 2023

Automatic robotic drilling is a widely used way of fastening in the field of
aircraft assembly and is worth studying continuously. Drilling accuracy is one
of the most remarkable properties of the system, which is directly related to
the absolute positioning accuracy of the robot end effector. Due to the
kinematic errors and gravity of the robotic system itself, the nominal pose and
the actual pose of the end effector are no longer consistent with each other. It
is necessary to keep the high positioning accuracy of the system. In this paper,
an automatic robotic drilling system with high positioning accuracy is proposed.
Generally, there are two methods to improve positioning accuracy: off-line
calibration and on-line adjustment. An off-line calibration based on the DH
method is proposed to identify and modify the parameter errors of the robot. A
6- degree of freedom industrial robot is integrated into the drilling system.
After the kinematic error modeling of the robot is established, the sample
points in the reachable workspace of the robot are measured, the kinematic
errors are identified and compensated, and the calibration process is achieved.
Then an on-line pose measurement and adjustment of the end effector based on a
laser tracker are developed. Transforming relations between coordinate systems
of all parts of the drilling system are firstly obtained accurately. With the
robotic drilling end-effector as the working module and the laser tracker as the
measuring module, A closed-loop control system for positioning accuracy is
established. By measuring the actual pose of the end-effector and comparing it
with the nominal pose, the pose of the end-effector is adjusted in real-time.
The experiment results indicate that after pose measurement and adjustment the
positioning accuracy of the end effector meets the accuracy requirements.
eVTOL Flight: Forecasting Future Training Requirements in an Emerging
Aviation Market
Authors: Emerson Samantha N. , Rizzardo Cait , Waggenspack Luke , Osman Maria Chaparro , Halverson Kent C. , Ellis Steve , Haley Don
Published: March 2023

Most emerging electric vertical takeoff and landing (eVTOL) aircraft feature
distributed electric propulsion systems with automation features that simplify
operations for future pilots. In theory, increasing automation levels should
reduce pilot workload, decrease training time, and improve performance
consistency. Air Education and Training Command Detachment 62 (AETC/Det 62)
sought to test this theory as part of a larger study involving 70+ participants,
two eVTOL platform simulators, and multimodal assessments of flight performance.
In the present report, we compared expert ratings of flight performance of
pilots who do not have prior pilot experience or training (herein referred to as
ab initio pilots; i.e., 0 flight hours) to those of experienced pilots (i.e.,
>300 flight hours) in either a semi-automated or highly-automated simulated
eVTOL platform. All participants received a brief orientation of the controls,
then flew a scripted flight profile four times with guidance from an instructor
pilot. The fourth and final flight profile was flown without any instructional
guidance in order to assess unassisted performance. Instructor pilots rated the
quality of hover, takeoff, en-route navigation, and approach and landing
maneuvers on a 4-point scale. Experienced pilots overall outperformed ab initio
pilots; however, the two groups showed similar learning trajectories for basic
eVTOL flight operations over a 2-hour period of learning. In some cases (e.g.,
takeoff in the highly-automated platform), ab initio pilots reached similar
performance levels as experienced pilots during the learning profile. Although
the present study focused only on basic flight skills, results suggest that both
ab initio and experienced pilots can rapidly gain proficiency in basic eVTOL
operations.
Stitching The Digital Thread, Creating The Product Digital
Quilt
Authors: Hamada Mohamed Y. , Rabelo Luis
Published: March 2023

The making of a quilt is an interesting process. Historically, a quilt is a
canvas of work made from old pieces of cloth cut into squares or whatever shape
that make a nice connected pattern and then stitched together. The quilt could
be random pieces that is not related to each other. In most recent years and
more common cases, a quilt is made of different pieces of patches that are
connected and laid out in a special way to tell a story. Not only does it
portray a story that is put together in a certain sequence, but it also stiches
the pieces of the quilt into a nice and complete narrative. A story that one can
understand just by looking at the quilt spread and unfolded. Much like the
making of a quilt that has a story to tell, a Product Digital Quilt will tell
the story of a product.

The Digital Product Quilt replaces the conventional way of telling a product
story. The traditional product story is a method that is serially connecting
multiple product life cycle silos together. This process is usually error prone,
difficult to understand and hard to maintain.

The Digital Product Quilt is made up of multiple pieces of the puzzle that makes
a product story and the source of truth. At the center of the Product Digital
Quilt is the Digital Model which represent the source of truth for the product.
The first core band of the Product Digital Quilt, surrounding the Digital Model,
are Requirements, Engineering, Analysis, Manufacturing, Integration and Fielding
the product to the end user which includes Sustainability and Maintenance. The
different pieces of the Product Digital Quilt are stitched with many different
digital threads such as the System, Software, hardware and quality threads.
Comparative CFD Analysis of Different Angles of Trailing-Edge Fowler
Wing Flaps
Authors: Bhavsar Kathan , Kartha Jessica
Published: March 2023

This paper focuses on a case study to compare the performances of Fowler wing
flaps that are used on the trailing edge of modern-day commercial airliners. The
aim is to observe trends in coefficients of lift (Cl) and drag
(Cd) with varying flap angles of release on a single-slotted
Fowler flap and arrive at the most efficient flap configuration for flight. A
series of two-dimensional analyses are carried out using computational fluid
dynamics (CFD) to examine the flow separation and occurrence of stalls between
the different angles of flap deflection. A two-equation, k-ω shear stress
transport (SST) turbulence model is used as it helps in better prediction of
flow separation and boundary layer studies. Since the study is carried out for
such passenger carriers, the study focuses on the lower transonic ranges of Mach
number 0.7-0.9 with a Reynolds number range of 400,000 to 500,000 considering a
scaled-down model and upon taking inspiration from related literature. The flaps
are analyzed at various angles of release (α) such as 0°, 15°, 25°and 50°, which
are selected considering the angles that they are commonly deflected to during
take-off and landing scenarios. A NACA0012 symmetrical airfoil is chosen with a
fixed chord length for the wing and kept at 0° Angle of Attack (AoA) with
subsequent trailing edge Fowler flaps employed for examination. A data-driven
approach is followed for the investigation of characteristics represented by the
different designs of the Fowler flap, thus typical lift curve plots
(Cl vs α), drag plots (Cd vs α), and lift-to-drag
ratio (Cl/Cd) plots (Cl/Cd vs α)
graphs are presented to understand the comparative study. The results are
discussed with respect to the data observed in the graphs and a viable
conceptual configuration for the single-slotted Fowler flap is selected. This
insight, research, and design have led to the development of the research paper
and it is hoped that this comparative study can be used to conduct further
research in the field of aeronautics.
Znaczenie pojęcia „pieszy wchodzący” – głos polemiczny
Authors: Krzemień Piotr
Published: March 2023

Opracowanie jest kontynuacją publikacji autora dotyczących zmian ustawy Prawo o ruchu drogowym w zakresie pierwszeństwa pieszych. Jednocześnie stanowi polemikę z poglądem polegającym na stwierdzeniu, że pieszy wchodzący na przejście to taki „który zaraz wkroczy na przejście” i w praktyce znajduje się poza przejściem dla pieszych, czyli w małej odległości od krawędzi jezdni i przejścia.

The meaning of term “a pedestrian entering a zebra crossing” – a polemical voice
The article is a follow-up to the author’s publication on the amendments to the Act on Road Traffic in the field of pedestrians’ right of way. It is also a polemic against the view that a pedestrian entering a zebra crossing is one “that is about to enter the crossing” while he/she is actually outside the crossing proper, in other words at a small distance from the curb and the crossing.
Skanowanie 3D w badaniach wypadków drogowych
Authors: Mikulec Roman , Motl Jakub , Tmejová Tereza , Svatý Zdeněk
Published: March 2023

W niniejszym artykule przedstawiono zagadnienia z dziedziny dokumentowania wypadków drogowych z zastosowaniem skanowania 3D oraz praktyczne doświadczenia autorów w wykorzystaniu tej metody skanowania na miejscu wypadku, jak również przy późniejszym przetwarzaniu wyników skanowania. W szczególności opisano różne warunki, w jakich można sporządzać dokumentację dowodową oraz podano rozwiązania niektórych praktycznych problemów związanych z wykorzystaniem skanerów 3D. Na zakończenia przedstawiono zalecenia dotyczące wykorzystania skanerów 3D do efektywnego dokumentowania wypadków drogowych z uwzględnieniem wymagań czasowych oraz wielkości danych w związku z koniecznością ich archiwizacji.

3D scanning in road accident investigations
This article presents the issues of documentation of traffic accidents using 3D scanning and the practical experience of the authors of this article in its use at the accident scene and subsequent data processing. In particular, the various conditions under which documentation can be performed and the solution of some practical problems related to the use of 3D scanners are described. Finally, the authors' recommendations for the use of 3D scanners for effective documentation of traffic accidents are suggested, taking into account the time requirements and the size (volume) of the data in relation to the need for archiving.
O niektórych cechach nieoryginalnych części zamiennych używanych do napraw nadwozi
Authors: Lubowicz Janusz , Szcześniak Janusz
Published: March 2023

W artykule przedstawiono wstępne wyniki porównawczych badań wytrzymałościowych i cech antykorozyjnych oryginalnych części nadwozi samochodowych i ich zamienników. Wyniki tych badań pozwalają wnioskować o przydatności niektórych zamienników, a równocześnie mogą być wstępem do wypracowania kryteriów jakościowych dopuszczenia do użytkowania zamienników części nadwozi.

About some features of non-original spare parts used for car body repair
Preliminary results of comparative strength tests and anti-corrosion characteristics of original car body parts and replacements of these parts are presented. The results allow concluding about the suitability of some substitutes, and at the same time may be a prelude to the development of quality criteria for obtaining a certificate for release to service of replacements for body parts.