bluuebunny/crossref_metadata_2025 huggingface dataset:
Spatiotemporal dynamics and environmental determinants of scrub typhus in Anhui Province, China, 2010–2020
Authors: Wei Xianyu , He Junyu , Yin Wenwu , Soares Magalhaes Ricardo J. , Wang Yanding , Xu Yuanyong , Wen Liang , Sun Yehuan , Zhang Wenyi , Sun Hailong
Published: February 2023

This study aims to describe the epidemiological characteristics of scrub typhus, detect the spatio-temporal patterns of scrub typhus at county level, and explore the associations between the environmental variables and scrub typhus cases in Anhui Province. Time-series analysis, spatial autocorrelation analysis, and space–time scan statistics were used to explore the characteristics and spatiotemporal patterns of the scrub typhus in Anhui Province. Negative binomial regression analysis was used to explore the association between scrub typhus and environmental variables. A total of 16,568 clinically diagnosed and laboratory-confirmed cases were reported from 104 counties of 16 prefecture-level cities. The number of female cases was higher than male cases, with a proportion of 1.32:1. And the proportion of cases over 65 years old was the highest, accounting for 33.8% of the total cases. Two primary and five secondary high-risk clusters were detected in the northwestern, northeastern, and central-eastern parts of Anhui Province. The number of cases in primary and secondary high-risk clusters accounted for 60.27% and 3.00%, respectively. Scrub typhus incidence in Anhui Province was positively correlated with the population density, normalized difference vegetation index, and several meteorological variables. The mean monthly sunshine duration with 3 lags (SSD_lag3), mean monthly ground surface temperature with 1 lag (GST_lag1), and mean monthly relative humidity with 3 lags (RHU_lag3) had the most significant association with increased cases of scrub typhus. Our findings indicate that public health interventions need to be focused on the elderly farmers in north of the Huai River in Anhui Province.
Hedonism as a motive for information search: biased information-seeking leads to biased beliefs
Authors: Jiwa Matthew , Cooper Patrick S. , Chong Trevor T-J. , Bode Stefan
Published: February 2023

Confirmation bias in information-search contributes to the formation of polarized echo-chambers of beliefs. However, the role of valence on information source selection remains poorly understood. In Experiment 1, participants won financial rewards depending on the outcomes of a set of lotteries. They were not shown these outcomes, but instead could choose to view a prediction of each lottery outcome made by one of two sources. Before choosing their favoured source, participants were first shown a series of example predictions made by each. The sources systematically varied in the accuracy and positivity (i.e., how often they predicted a win) of their predictions. Hierarchical Bayesian modeling indicated that both source accuracy and positivity impacted participants’ choices. Importantly, those that viewed more positively-biased information believed that they had won more often and had higher confidence in those beliefs. In Experiment 2, we directly assessed the effect of positivity on the perceived credibility of a source. In each trial, participants watched a single source making a series of predictions of lottery outcomes and rated the strength of their beliefs in each source. Interestingly, positively-biased sources were not seen as more credible. Together, these findings suggest that positively-biased information is sought partly due to the desirable emotional state it induces rather than having enhanced perceived credibility. Information sought on this basis nevertheless produced consequential biased beliefs about the world-state, highlighting a potentially key role for hedonic preferences in information selection and subsequent belief formation.
Range-wide whole-genome resequencing of the brown bear reveals drivers of intraspecies divergence
Authors: de Jong Menno J. , Niamir Aidin , Wolf Magnus , Kitchener Andrew C. , Lecomte Nicolas , Seryodkin Ivan V. , Fain Steven R. , Hagen Snorre B. , Saarma Urmas , Janke Axel
Published: February 2023

Population-genomic studies can shed new light on the effect of past demographic processes on contemporary population structure. We reassessed phylogeographical patterns of a classic model species of postglacial recolonisation, the brown bear (Ursus arctos), using a range-wide resequencing dataset of 128 nuclear genomes. In sharp contrast to the erratic geographical distribution of mtDNA and Y-chromosomal haplotypes, autosomal and X-chromosomal multi-locus datasets indicate that brown bear population structure is largely explained by recent population connectivity. Multispecies coalescent based analyses reveal cases where mtDNA haplotype sharing between distant populations, such as between Iberian and southern Scandinavian bears, likely results from incomplete lineage sorting, not from ancestral population structure (i.e., postglacial recolonisation). However, we also argue, using forward-in-time simulations, that gene flow and recombination can rapidly erase genomic evidence of former population structure (such as an ancestral population in Beringia), while this signal is retained by Y-chromosomal and mtDNA, albeit likely distorted. We further suggest that if gene flow is male-mediated, the information loss proceeds faster in autosomes than in X chromosomes. Our findings emphasise that contemporary autosomal genetic structure may reflect recent population dynamics rather than postglacial recolonisation routes, which could contribute to mtDNA and Y-chromosomal discordances.
Observation of long-range orbital transport and giant orbital torque
Authors: Hayashi Hiroki , Jo Daegeun , Go Dongwook , Gao Tenghua , Haku Satoshi , Mokrousov Yuriy , Lee Hyun-Woo , Ando Kazuya
Published: February 2023

Modern spintronics relies on the generation of spin currents through spin-orbit coupling. The spin-current generation has been believed to be triggered by current-induced orbital dynamics, which governs the angular momentum transfer from the lattice to the electrons in solids. The fundamental role of the orbital response in the angular momentum dynamics suggests the importance of the orbital counterpart of spin currents: orbital currents. However, evidence for its existence has been elusive. Here, we demonstrate the generation of giant orbital currents and uncover fundamental features of the orbital response. We experimentally and theoretically show that orbital currents propagate over longer distances than spin currents by more than an order of magnitude in a ferromagnet and nonmagnets. Furthermore, we find that the orbital current enables electric manipulation of magnetization with efficiencies significantly higher than the spin counterpart. These findings open the door to orbitronics that exploits orbital transport and spin-orbital coupled dynamics in solid-state devices.
Combining sensors and actuators with electrowetting-on-dielectric (EWOD): advanced digital microfluidic systems for biomedical applications
Authors: Tong Zhaoduo , Shen Chuanjie , Li Qiushi , Yin Hao , Mao Hongju
Published: February 2023

Typical forms of a combination of electrowetting-on-dielectric (EWOD) technology with sensing and other microfluidic manipulation techniques are reviewed from a technical perspective, including the purposes, significance, and biomedical applications.
Fluorescence quantification of inorganic particle dispersity for anti-aging evaluation of polymer composites
Authors: Xu Qinghong , Sun Ziqi , Tian Rui , Li Kaitao , Lu Chao
Published: February 2023

We have proposed a fluorescent quantification strategy to determine the dispersity of inorganic particles for the assessment of the anti-aging behaviors of polymer composites.
Enhanced lithium polysulfide adsorption on an iron-oxide-modified separator for Li–S batteries
Authors: Wu Jiao , Feng Qingguo , Wang Yuchao , Wang Jinxian , Zhao Xin , Zhan Longsheng , Liu Mengjie , Jin Zhaoqing , Chen Zhiyan , Lei Yongpeng
Published: February 2023

The polar IO-700 could effectively adsorb LiPSs and inhibit their shuttle effect, so its use as a separator modifier for Li–S batteries provides a long cycle performance with a low rate of capacity decay of 0.0487% per cycle.
Regio- and chemoselective hydroamination of unactivated alkenes with anthranils via NiH-catalysis
Authors: Zheng Yan-Long , Liang Di-Yu , Ma Hong-Bin , Meng Fan-Cheng , Wang Tie
Published: February 2023

A NiH-catalyzed polarity-reversed hydroamination of β,γ-, γ,δ- and δ,ε-unsaturated alkenes with anthranils was developed to access diverse arylamines bearing a carbonyl or alcohol functionality with 100% atom efficiency.
Two-dimensional population balance modelling and validation of combined cooling and antisolvent crystallization of l-asparagine monohydrate
Authors: Lenka Maheswata , Bhoi Stutee , Sarkar Debasis
Published: February 2023

Combining cooling and antisolvent modes of crystallization is advantageous as it may significantly improve the process performance.
Fabrication of a highly dispersed Co3O4-modified MOF-derived ZnO@ZnS porous heterostructure for efficient photocatalytic hydrogen production
Authors: Wang Wen , Xiao Weiming , Zhu Yuxin , Liu Sanmei , Wang Shuhua , Chen Chao
Published: February 2023

A highly dispersed Co3O4-modified ZnO@ZnS porous heterostructure was prepared via a designed bimetallic ZnCo-ZIF@ZIF-8 precursor for water splitting.
Synthesis of zirconium-based metal–organic frameworks with iron(ii) clathrochelate ligands
Authors: Shetty Suchetha , Idrees Karam B. , Xie Haomiao , Alameddine Bassam , Farha Omar K.
Published: February 2023

Zirconium-based metal organic frameworks (MOFs) are of great significance in supramolecular coordination chemistry, mainly as catalysts, due to their chemical stability and structural diversity.
Sequential mechanism in H3+ formation dynamics on the ethanol dication
Authors: Gope Krishnendu , Bittner Dror M. , Strasser Daniel
Published: February 2023

The ethanol dication exhibits rich fragmentation dynamics, including multiple H atom migration, concerted and sequential 3-body breakup. Using mass-scaled Dalitz plots, mechanistic information is extracted from measured 3-body momentum correlations.
The electrostatic effect and its role in promoting electrocatalytic reactions by specifically adsorbed anions
Authors: Chen Wei , Zhang Lu-Lu , Wei Zhen , Zhang Meng-Ke , Cai Jun , Chen Yan-Xia
Published: February 2023

The adsorption of anions and its impact on electrocatalytic reactions are fundamental topics in electrocatalysis.
Simultaneous electrical impedance and optical absorption spectroscopy for rapid characterization of oxygen vacancies and small polarons in doped ceria
Authors: Kalaev D. , Tuller H. L.
Published: February 2023

Novel σ–α method, applied under non-steady state conditions, enables an accelerated and detailed study of oxygen vacancy and small polaron transport in praseodymium doped ceria as functions of oxygen non-stoichiometry and temperature.
Substitution of Ca2+ and changes in the H-bond network near the oxygen-evolving complex of photosystem II
Authors: Mandal Manoj , Saito Keisuke , Ishikita Hiroshi
Published: February 2023

Ca2+, which is a prerequisite for oxygen evolution at the catalytic Mn4CaO5 cluster in photosystem II, is replaced with other alkaline earth metals to investigate its influence on the H-bond network.
Computational insights into the reactivity for the [2+5] cycloaddition reactions of norbornene-linked group 14 element/P-based and Si/group 15 element-based frustrated Lewis pairs with benzaldehyde
Authors: Zhang Zheng-Feng , Su Ming-Der
Published: February 2023

Only Si/P-based, Si/N-based, and Si/As-based FLPs can facilitate the [2+5] cycloaddition reaction with benzaldehyde both kinetically and thermodynamically.
Artificial synapse based on 1,4-diphenylbutadiyne with femtojoule energy consumption
Authors: Liu Jiesong , Li Zhengjie , Jia Caihong , Zhang Weifeng
Published: February 2023

Fast Bienenstock–Cooper–Munro learning rules (BCM), ultra-low energy consumption (∼25 fJ per spike), linear and large conductance changes have been successfully obtained in the 1,4-diphenylbutadiyne (DPDA) memristor device.
Probing plasmon-induced surface reactions using two-dimensional correlation vibrational spectroscopy
Authors: Singh Ruchi , Yadav Vikas , Siddhanta Soumik
Published: February 2023

Two-dimensional correlation spectroscopy can be used to probe plasmon assisted surface reactions efficiently and monitor intermediates and products simultaneously in real time.
Elucidating the interplay of local and mesoscale ion dynamics and transport properties in aprotic ionic liquids
Authors: Cosby Tyler , Stachurski Christopher D. , Mantz Robert A. , Trulove Paul C. , Durkin David P.
Published: February 2023

Local dynamic heterogeneity in ILs is marked by separation in ion dynamics at nearest neighbor and next-nearest neighbor distances. The separation is temperature and chemical structure dependent and drives polarization across mesoscale aggregates.
Examining the substituent effect on mycosporine-inspired ultraviolet filters
Authors: Whittock Abigail L. , Cowden Adam M. , Wills Martin , Stavros Vasilios G.
Published: February 2023

The photoprotective properties of four biomimetic molecules inspired by mycosporines have been investigated as potential UV filters.
Role of the redox state of cerium oxide on glycine adsorption: an experimental and theoretical study
Authors: Kosto Yuliia , Barcaro Giovanni , Kalinovych Viacheslav , Franchi Stefano , Matvija Peter , Matolínová Iva , Prince Kevin C. , Matolín Vladimír , Skála Tomáš , Tsud Nataliya , Carravetta Vincenzo
Published: February 2023

Thermal decomposition of glycine molecules on cerium oxide films is defined by the type of cerium cations on the surface.
Antimonene: a tuneable post-graphene material for advanced applications in optoelectronics, catalysis, energy and biomedicine
Authors: Carrasco Jose A. , Congost-Escoin Pau , Assebban Mhamed , Abellán Gonzalo
Published: February 2023

Antimonene is considered one of the most promising 2D materials for a large number of applications, ranging from optoelectronics or energy storage to biomedicine. This review discusses recent advances in its synthesis methods, characterization, properties, and applications.
Substrate engineering for wafer-scale two-dimensional material growth: strategies, mechanisms, and perspectives
Authors: Zhao Tiange , Guo Jiaxiang , Li Taotao , Wang Zhen , Peng Meng , Zhong Fang , Chen Yue , Yu Yiye , Xu Tengfei , Xie Runzhang , Gao Pingqi , Wang Xinran , Hu Weida
Published: February 2023

This review focuses on the existing strategies and underlying mechanisms, and discusses future directions in epitaxial substrate engineering to deliver wafer-scale 2D materials for integrated electronics and photonics.
In situ growth of metal–organic frameworks in nanochannels for highly sensitive microcystin-LR detection
Authors: Zhang Wei-Qi , Tu Yi-Dan , Wang Xu-Gang , Huang Yu , Xia Fan
Published: February 2023

Harmful algal blooms lead to cyanobacteria toxins increase in natural water. A novel nanochannel-based sensing system utilizing metal–organic frameworks and DNA aptamers was developed for highly sensitive detecting microcystin-LR in real water.
Electrochemical experiments define potentials associated with binding of substrates and inhibitors to nitrogenase MoFe protein
Authors: Chen Ting , Ash Philip A. , Seefeldt Lance C. , Vincent Kylie A.
Published: February 2023

We associate potentials with the binding of substrates and inhibitors, H+, C2H2, CO and MeNC, to nitrogenase MoFe protein by coupling electrochemical control with gas chromatography analysis and in situ infrared spectroscopy.
Tumour associated vasculature-on-a-chip for the evaluation of microbubble-mediated delivery of targeted liposomes
Authors: Bourn Matthew D. , Mohajerani Safoura Zahed , Mavria Georgia , Ingram Nicola , Coletta P. Louise , Evans Stephen D. , Peyman Sally A.
Published: February 2023

Increased accumulation of targeted liposomes was observed in cultures mimicking tumour-associated vasculature, when compared to healthy vasculature cultures. Microbubble-mediated liposome delivery was found to further increase liposome accumulation.
Combining multi-scale simulations and experiments to unveil the adsorption of methylene blue in graphene tridimensional-based materials
Authors: Leão Mayara B. , Vendrame Laura F. O. , Fagan Solange B. , Zanella Ivana , Jauris Iuri M. , Bordin José R. , de Matos Carolina F.
Published: February 2023

Our work brings outstanding contributions to the theoretical–experimental understanding of the process of adsorption of dye molecules in three-dimensional graphene materials with different pore sizes and degrees of oxidation.
TiO2-based catalytic systems for the treatment of airborne aromatic hydrocarbons
Authors: Bathla Aadil , Younis Sherif A. , Kim Ki-Hyun , Li Xiaowei
Published: February 2023

This work highlights the photo/thermo-catalytic potential of TiO2-based materials toward aromatic hydrocarbons based on the evaluation of their performance. Future prospects of TiO2-based catalysts are also discussed to help expand their utility under real-world conditions.
Directional Bloch surface wave coupling enabled by magnetic spin-momentum locking of light
Authors: Luo Kaiwen , Huang Zhijing , Lv Xianpeng , Qiu Wentao , Guan Heyuan , Yang Tiefeng , Grosjean Thierry , Lu Huihui
Published: February 2023

We achieve a directional nano-routing of BSWs with circularly polarized illumination. Such a directional coupling phenomenon is proved to be solely mediated by the optical magnetic field.
AIE in the halogenated anils and their utilization as fluorescent probes for explosive nitro-aromatics
Authors: Ahangar Aadil A. , Ahmad Ishtiyaq , Dar Aijaz A.
Published: February 2023

AIE in a series of non-emissive halogenated Anils has been established spectroscopically and substantiated through dynamic light scattering. The resultant AIEgens with good quantum yields have been utilized for the sensing of nitro-aromatics.
Efficient degradation of metronidazole wastewater over MIL-101(Fe) Fenton catalysts
Authors: Zhang Xu , Lyu Yang , Zhang Jie , He Bai , Xiong Wei , Jiang Songshan
Published: February 2023

Complete degradation of high concentration metronidazole wastewater with low dosage of MIL-101(Fe) by Fenton catalysts.
Luminescent and photocatalytic activity of NaGd(MoO4)2:Dy3+/Eu3+ and NaGd(WO4)2:Dy3+/Eu3+ nanorods for efficient sensing and degradation of the antibiotic drug, nitrofurantoin
Authors: Devi Swaita , Singhaal Richa , Sen Charanjeet , Sheikh Haq Nawaz
Published: February 2023

In this contribution, we explored NaGd(MoO4)2:Dy3+/Eu3+ and NaGd(WO4)2:Dy3+/Eu3+ nanorods as a photoluminescence probe and photocatalyst for the efficient sensing and removal of nitrofurantoin (NFT), respectively.
Synthesis of 1,2-oxaphosphinane 2-oxides and 1,2-oxaphosphinine 2-oxides: δ-phosphonolactones and δ-phosphinolactones
Authors: Xu Jiaxi
Published: February 2023

Synthetic methods include cyclizations for construction of P–O, O–C, P–C, and C–C bonds, annulations involving [4+2], [5+1], and [3+3] fashions, cycloadditions, ring contractions and expansions.
Visible light-promoted synthesis of 4,6a-dihydropyrrolo[3,4-c]pyrrole-1,3(2H,3aH)-dionesvia[3+2] cycloaddition reaction of 2H-azirines with maleimides
Authors: Guo Hao , Wang Huahao , Zhao Hongyi , Zhang Dongfeng
Published: February 2023

Diastereoselective synthesis of pyrrolo[3,4-c]pyrrole-1,3-dione derivitives from 2H-azirines andN-substituted maleimides through an efficient and environmentally friendly visible light-induced cycloaddition reaction.
DTBP-mediated controlled oxidative C–S bond cleavage/annulation cascade: construction of indenones
Authors: Jafarpour Farnaz , Rahimi Banafshe
Published: February 2023

The cascade involves the controlled formation of carbonyls from benzyl thioethers followed by the annulation of alkynes to offer privileged indenone skeletons.
Highly regioselective synthesis of lactamsviacascade reaction of α,β-unsaturated ketones, ketoamides, and DBU as a catalyst
Authors: Qin Xin , Zhang Jinhai , Wang Zhan-Yong , Song Yimei , Yang Yixiao , Zhang Wenhai , Liu Hongxin
Published: February 2023

The β,γ-positions of α,β-unsaturated ketones were reacted with ketoamides, with the hydrogen of the amide as the key factor to construct lactams.
Graphene oxide as a multi-functional additive for compatilizer, enhancer, and barrier in ethylene vinyl alcohol copolymer/aramid pulp composites
Authors: Yang Xuyu , Ye Yingying , Liu Jiayan , Liu Weijun , Xiong Xianqiang , He Zhicai
Published: February 2023

To improve the thermal, mechanical, and barrier properties of ethylene vinyl alcohol copolymer (EVOH)/aramid pulp (AP), graphene oxide (GO) was used as a compatilizer, enhancer, and barrier to fabricate EVOH-based composites.
A wear and heat-resistant hydrophobic fluoride-free coating based on modified nanoparticles and waterborne-modified polyacrylic resin
Authors: Yu Bin , Liu Huicong , Chen Haining , Li Weiping , Zhu Liqun , Liang Weitao
Published: February 2023

Hydrophobic coatings have attracted extensive research due to their broad application prospects.
Alternative and facile production pathway towards obtaining high surface area PtCo/C intermetallic catalysts for improved PEM fuel cell performance
Authors: Heizmann Philipp A. , Nguyen Hien , von Holst Miriam , Fischbach Andreas , Kostelec Mitja , Gonzalez Lopez Francisco Javier , Bele Marjan , Pavko Luka , Đukić Tina , Šala Martin , Ruiz-Zepeda Francisco , Klose Carolin , Gatalo Matija , Hodnik Nejc , Vierrath Severin , Breitwieser Matthias
Published: February 2023

A novel PtCo/C based PEMFC electrocatalyst was investigated in real fuel cells under application-relevant conditions. The corresponding MEAs show superior performance compared to reference materials due to more suitable nanoparticle sizes.
Computational and experimental studies on the micellar morphology and emission mechanisms of AIE and H-bonding fluorescent composites
Authors: Zhou Guangying , Cheng Xiaomeng , Yang Jian , Zhu Yanyan , Li Hongping
Published: February 2023

Computational and experimental approaches on the CXL-aided self-assembled morphology and emission mechanisms of AIE and H-bond featured fluorescent composites.
Cellulose-based hydrogel for adsorptive removal of cationic dyes from aqueous solution: isotherms and kinetics
Authors: Poornachandhra Chidamparam , Jayabalakrishnan Rajamani M , Prasanthrajan Mohan , Balasubramanian Govindaraj , Lakshmanan Arunachalam , Selvakumar S , John Joseph Ezra
Published: February 2023

Nanocellulose based hydrogel beads for efficient removal and recovery of dyes from textile industry effluents.
A general method to predict optical rotations of chiral molecules from their structures
Authors: Ji Hai-Feng
Published: February 2023

The relationship of the chiroptical response of a molecule to its absolution configuration does not exist now.
Ultrathin electrochemical layer tailoring of lithiophilic materials with 3D hierarchical configuration for lithium metal batteries: Sn/Cu6Sn5@Cu2+1O nanowires on Cu foam
Authors: Lee Garam , Ha Jaeyun , Lee Jinhee , Kim Yong-Tae , Choi Jinsub
Published: February 2023

A hierarchical Cu2+1O nanowire covered ultrathin Sn/Cu6Sn5 alloy composite on copper foam is produced in 90 minutes by a fully electrochemical wet process for use as a stable Li metal anode to prevent the formation of Li dendrite.
Piezocatalytic performance enhancement using the sandwich structure of a PVDF-HFP/graphene film
Authors: Liu Ya , Tong Wangshu , Song Wanting , Cao Tingting , Liu Yulun , Wang Lingchao , Wang Zhihao , Zhang Yihe
Published: February 2023

A PVDF-HFP/graphene piezocatalytic film with a sandwich structure was prepared. Under the piezoelectric field of PVDF-HFP, the exposed graphene on the surface of the sandwich film provided the charges to react with the pollutants.
First-principles study on ultrafast Li-ion diffusion in halospinel Li2Sc2/3Cl4 through multichannels designed by aliovalent doping
Authors: Hyun Suseong , Chun Hoje , Hong Minjoon , Kang Joonhee , Han Byungchan
Published: February 2023

Create Li-ion multichannels and achieve excellent ionic conductivity by doping cost-effective Fe2+ in halospinel.
Calcium silicate/bortezomib combinatory therapy for multiple myeloma
Authors: Cao Liqin , Gu Huiyao , Zhang Zhaowenbing , Zhang Enfan , Chang Jiang , Cai Zhen
Published: February 2023

Calcium silicate-enhanced anti-myeloma effect of Bortezomib (BOR) by enhancing cell cycle arrest and inhibition of NF-κB pathway by BOR.
Core–shell bioceramic fiber-derived biphasic granules with adjustable core compositions for tuning bone regeneration efficacy
Authors: Bao Zhaonan , Yang Jun , Shen Jian , Wang Cong , Li Yifan , Zhang Yan , Yang Guojing , Zhong Cheng , Xu Sanzhong , Xie Lijun , Shen Miaoda , Gou Zhongru
Published: February 2023

Silicate-based biomaterials—clinically applied fillers and promising candidates—can act as a highly biocompatible substrate for osteostimulative osteogenic cell growthin vitroandin vivo.
Multilamellar ceramide core-structured microvehicles with substantial skin barrier function recovery
Authors: Shin Kyounghee , Lee Kun Bong , Hwang Jee-Hyun , Lee Boryeong , Ryu Hyunsun , Noh Minjoo , Lee Jun Bae , Nam Yoon Sung , Lim Kyung-Min , Kim Jin Woong
Published: February 2023

A multilamellar ceramide microvehicle platform was established by using cellulose nanofibers-enveloped ceramide-rich lipid microparticles (CerMPs). Our CerMPs with molecular layer integrity showed notable skin barrier function recovery performance.
Accelerated polaron formation in perovskite quantum dots monitored via picosecond infrared spectroscopy
Authors: Nuber Matthias , Tan Qi Ying , Sandner Daniel , Yin Jun , Kienberger Reinhard , Soci Cesare , Iglev Hristo
Published: February 2023

Picosecond mIR-spectroscopy reveals polaron stabilization processes in perovskite quantum dots on a few ps time-scale, considerably faster than the bulk analogue.
Ultralow-power consumption photonic synapse transistors based on organic array films fabricated using a particular prepatterned-guided crystallizing strategy
Authors: Shen Zihong , Yang Zunxian , Zhou Yuanqing , Ye Yuliang , Ye Bingqing , Huang Qiaocan , Wu Wenbo , Hong Hongyi , Hong Zeqian , Meng Zongyi , Zeng Zhiwei , Ye Songwei , Cheng Zhiming , Lan Qianting , Wang Jiaxiang , Chen Ye , Zhang Hui , Guo Tailiang , Ye Yun , Weng Zhenzhen , Chen Yongyi
Published: February 2023

The prepattern-guided crystallization method was used to prepare array thin film transistors. The photonic synapses realized synaptic behaviour with 0.036 fJ per spike and demonstrated many important functions.
Identifying different electronic transport mechanisms in nanoporous inorganic electrides – a combined study using Hall measurements and electron paramagnetic resonance spectroscopy
Authors: Dinter Julius K. , Lange Jurek , Hofmann Detlev M. , Plaza Fernández J. Fabián , Post Angel , Chatterjee Sangam , Elm Matthias T. , Klar Peter J.
Published: February 2023

Temperature-dependent Hall measurements and electron paramagnetic resonance spectroscopy reveal that three different transport mechanisms contribute to the electronic properties of the inorganic electride [Ca24Al28O64]4+(4e−).
Sustainable energy technologies for the Global South: challenges and solutions toward achieving SDG 7
Authors: Kay Lup Andrew Ng , Soni Vikram , Keenan Benjamin , Son Jaewon , Taghartapeh Mohammad Ramezani , Morato Marcelo Menezes , Poya Yalinu , Montañés Rubén M.
Published: February 2023

Decentralization of energy generation to minimize energy distribution costs and maximize local energy production capacity.
Preparation of two kinds of membranes with reverse wettability from waste masks for continuous oil/water separation
Authors: Ning Lianchao , Liu Yi , Luo Yang , Han Yaxin , Zhang Longfei , Zhang Ming
Published: February 2023

Resourceful use of waste masks (WMs) has become an important challenge for humanity with the spread of the coronavirus disease (COVID-19).
Visualization of domain structure and piezoelectric energy harvesting in a ferroelectric metal–ligand cage
Authors: Prajesh Neetu , Naphade Dipti R. , Yadav Ashok , Kushwaha Vikash , Praveenkumar Balu , Zaręba Jan K. , Anthopoulos Thomas D. , Boomishankar Ramamoorthy
Published: February 2023

A metal–organic cage exhibits ferro- and piezoelectric properties as visualized by its domain structure using PFM and utility in piezoelectric energy harvesting properties. This is a rare observation in supramolecular metal–organic cages.
A blade-like CoZn metal organic framework-based flexible quasi-solid Zn-ion battery
Authors: Zhu Yajun , Han Tianli , Lin Xirong , Zhang Huigang , Hu Chaoquan , Liu Jinyun
Published: February 2023

We develop a blade-like CoZn metal organic framework-based flexible quasi-solid secondary battery, which is applicable for wearable devices such as foldable cellphones and pads.
Correction: Discovering atomistic pathways for supply of metal atoms from methyl-based precursors to graphene surface
Authors: Sangiovanni Davide G. , Faccio Ricardo , Gueorguiev Gueorgui Kostov , Kakanakova-Georgieva Anelia
Published: February 2023

Correction for ‘Discovering atomistic pathways for supply of metal atoms from methyl-based precursors to graphene surface’ by Davide G. Sangiovanni et al., Phys. Chem. Chem. Phys., 2023, 25, 829–837, https://doi.org/10.1039/D2CP04091C.
New palladium(ii) and platinum(ii) complexes with an ONS donor azo-thioether pincer ligand: synthesis, characterization, protein binding study and in vitro cytotoxicity
Authors: Das Akash , Saha Moumita , Mandal Subrata , Das Sanjib , Das Saha Krishna , Mondal Tapan K.
Published: February 2023

The in vitro cytotoxicity of new Pd(ii) and Pt(ii) complexes with an ONS donor azo-thioether pincer ligand has been studied.
An investigation of the allylation cascade reactions of substituted indigos
Authors: Perry Matthew J. , Willis Anthony C. , Bremner John B. , Keller Paul A.
Published: February 2023

In a continuation of the exploration of indigo cascade reactions, a series of –OMe, –Ph, –Br and –NO2 substituted indigos 1a–i were synthesised to probe electronic effects upon the outcome of allylation cascade reactions.
Polar solvent-free room temperature synthesis of CsPbX3 (X = Br, Cl) perovskite nanocubes
Authors: Guvenc C. Meric , Kocabas Askin , Balci Sinan
Published: February 2023

We herein demonstrate a polar solvent-free room temperature method for the synthesis of CsPbX3 (X = Br, Cl) nanocubes. In addition to the commonly used ligand pair of oleylamine and oleic acid, guanidinium (GA) has been used to passivate the surface of the nanocrystals.
Room temperature phosphorescence in longer-wavelength red light region found in benzothiadiazole-based dyes
Authors: Ishi-i Tsutomu , Kichise Rihoko , Park In Seob , Yasuda Takuma , Matsumoto Taisuke
Published: February 2023

Red phosphorescence emissions in the longer-wavelength region can be produced by introducing methoxy groups and bromine atoms into the electron-accepting benzothiadiazole dye.
Uncovering novel regulators of memory using C. elegans genetic and genomic analysis
Authors: Brandel-Ankrapp Katie L. , Arey Rachel N.
Published: February 2023

How organisms learn and encode memory is an outstanding question in neuroscience research. Specifically, how memories are acquired and consolidated at the level of molecular and gene pathways remains unclear. In addition, memory is disrupted in a wide variety of neurological disorders; therefore, discovering molecular regulators of memory may reveal therapeutic targets for these disorders. C. elegans are an excellent model to uncover molecular and genetic regulators of memory. Indeed, the nematode's invariant neuronal lineage, fully mapped genome, and conserved associative behaviors have allowed the development of a breadth of genetic and genomic tools to examine learning and memory. In this mini-review, we discuss novel and exciting genetic and genomic techniques used to examine molecular and genetic underpinnings of memory from the level of the whole-worm to tissue-specific and cell-type specific approaches with high spatiotemporal resolution.
The mechanisms of alkali therapy in targeting renal diseases
Authors: Imenez Silva Pedro Henrique , Wesson Donald E. , Wagner Carsten A.
Published: February 2023

Chronic kidney disease (CKD) is characterized by progressive reduction in kidney function and treatments aiming at stabilizing or slowing its progression may avoid or delay the necessity of kidney replacement therapy and the increased mortality associated with reduced kidney function. Metabolic acidosis, and less severe stages of the acid stress continuum, are common consequences of CKD and some interventional studies support that its correction slows the progression to end-stage kidney disease. This correction can be achieved with mineral alkali in the form of bicarbonate or citrate salts, ingestion of diets with fewer acid-producing food components or more base-producing food components, or a pharmacological approach. In this mini-review article, we summarize the potential mechanisms involved in the beneficial effects of alkali therapy. We also discuss the perspectives in the field and challenges that must be overcome to advance our understanding of such mechanisms.
Towards using 3D cellular cultures to model the activation and diverse functions of macrophages
Authors: Cutter Sean , Wright Mark D. , Reynolds Nicholas P. , Binger Katrina Jean
Published: February 2023

The advent of 3D cell culture technology promises to enhance understanding of cell biology within tissue microenvironments. Whilst traditional cell culturing methods have been a reliable tool for decades, they inadequately portray the complex environments in which cells inhabit in vivo. The need for better disease models has pushed the development of effective 3D cell models, providing more accurate drug screening assays. There has been great progress in developing 3D tissue models in fields such as cancer research and regenerative medicine, driven by desires to recreate the tumour microenvironment for the discovery of new chemotherapies, or development of artificial tissues or scaffolds for transplantation. Immunology is one field that lacks optimised 3D models and the biology of tissue resident immune cells such as macrophages has yet to be fully explored. This review aims to highlight the benefits of 3D cell culturing for greater understanding of macrophage biology. We review current knowledge of macrophage interactions with their tissue microenvironment and highlight the potential of 3D macrophage models in the development of more effective treatments for disease.
Comment, au fil du temps, l’ocytocine est devenue l’hormone de l’attachement
Authors: Freund-Mercier Marie-José
Published: February 2023

L’ocytocine est une molécule pléiotrope qui, en plus de son action facilitatrice au cours de l’accouchement et de l’allaitement, est impliquée dans des comportements sociaux et prosociaux comme l’attachement. Cet article présente, après un bref rappel historique, l’action de l’ocytocine pendant le réflexe d’éjection de lait. L’ocytocine est en effet indispensable à cette fonction vitale chez les mammifères. Elle est à la fois une neurohormone, libérée dans la circulation sanguine par les terminaisons axonales de la post-hypophyse, et un neuromodulateur, libéré dans l’hypothalamus par le soma et les dendrites des neurones magnocellulaires ocytocinergiques. D’autre part, l’ocytocine est également libérée dans le cerveau par les terminaisons axonales des neurones parvocellulaires et des collatérales d’axones des neurones magnocellulaires. La libération centrale de l’ocytocine est à l’origine de ses effets dans l’attachement, qu’il s’agisse de l’attachement maternel comme chez la ratte et la brebis ou de l’attachement entre les partenaires sexuels chez le campagnol des prairies, une des rares espèces de rongeurs monogames. Toutefois, ni l’injection d’ocytocine dans le cerveau, ni l’augmentation de l’expression du récepteur de l’ocytocine dans le noyau accumbens grâce à une technique de transfert de gène, ne rendent monogames des campagnols polygames. La transposition à l’espèce humaine des données obtenues chez l’animal reste problématique en raison principalement de la difficulté à modifier le taux d’ocytocine dans le cerveau.
Le trilostane
Authors: Kohlhauer Matthias , Tissier Renaud
Published: February 2023

Le trilostane (Vetoryl®) est un inhibiteur de la synthèse du cortisol indiqué dans le traitement de l’hypercorticisme d’origine hypophysaire ou surrénalienne chez le chien. Son mode d’action repose sur l’inhibition de la synthèse du cortisol et, dans une moindre mesure, de la synthèse de l’aldostérone. Compte tenu de la grande variabilité de réponse et de pharmacocinétique de cette molécule, la surveillance des animaux traités au trilostane doit être fréquente et la dose doit être régulièrement ajustée. Le suivi thérapeutique repose essentiellement sur la clinique et la réalisation régulière de tests de stimulation à l’ACTH. Lors d’une absence de réponse à ce test, le traitement doit être arrêté. En revanche, lorsque les résultats de ce test sont dans les normes ou montrent une cortisolémie trop élevée, l’augmentation de la posologie doit reposer sur l’évaluation clinique de l’animal et la persistance de signes cliniques compatibles avec un hypercorticisme. Même si le trilostane est généralement bien toléré, un hypocorticisme réversible peut parfois apparaître au cours du suivi. Des troubles du ionogramme (hyperkaliémie et hyponatrémie) liés à la baisse de la concentration d’aldostérone circulante sont parfois observés.
Phéochromocytome chez le chien
Authors: Krafft Émilie
Published: February 2023

Le phéochromocytome est une tumeur peu fréquente de la médullosurrénale. Les signes cliniques sont liés à une dysendocrinie induite par la sécrétion excessive et souvent pulsatile de catécholamines, mais également à l’invasion locale et à distance du processus tumoral. Ces signes sont très variés et souvent peu spécifiques et intermittents; le plus fréquemment sont présents de la faiblesse, de l’abattement, des phases de tachypnée/d’halètement et des malaises épisodiques. L’hypertension artérielle systémique peut être majeure mais évolue souvent par poussées et n’est donc pas toujours présente en consultation. Les anomalies observables lors du bilan sanguin de routine et à l’analyse d’urine sont peu spécifiques mais peuvent permettre d’exclure d’autres hypothèses. Le diagnostic repose sur la mise en évidence par imagerie d’une masse surrénalienne associée à la démonstration d’une production excessive de catécholamines par la mesure des concentrations sanguines et/ou urinaires de leurs métabolites, métanéphrine et normétanéphrine. Ces dosages étant encore peu disponibles en routine, le clinicien est souvent amené à réaliser un diagnostic d’exclusion en éliminant l’hypothèse d’une tumeur surrénalienne sécrétant d’autres hormones, par des tests endocriniens. Lorsque le doute persiste après ces examens, l’opportunité d’une ponction à l’aiguille fine échoguidée de la lésion pour analyse cytologique peut être considérée.
Diagnostic du syndrome de Cushing spontané chez le chien
Authors: Roux Camille , Bennaim Michaël
Published: February 2023

Le syndrome de Cushing est une endocrinopathie fréquente chez le chien. Il touche principalement les animaux âgés et certaines races sont prédisposées. Les signes cliniques, peu spécifiques, sont une polyuro-polydipsie, une polyphagie, une distension abdominale et des troubles cutanés. Plusieurs dosages biologiques peuvent permettre de renforcer une suspicion clinique comme, entre autres, la modification de l’activité de l’enzymologie hépatique. Les tests fonctionnels utilisés possèdent des qualités intrinsèques imparfaites et ainsi il est nécessaire de sélectionner les animaux au préalable afin d’augmenter la probabilité pré-test de ces derniers. L’interprétation des résultats est à réaliser à la lumière des éléments épidémiologiques, cliniques et biologiques. Après avoir confirmé un hypercorticisme, il est important d’en déterminer l’origine (hypophysaire ou surrénalien) afin de proposer la prise en charge thérapeutique la plus adaptée et de déterminer le pronostic. Il est notamment possible de se baser sur les résultats de tests dynamiques, le dosage de l’ACTH endogène et/ou sur des examens d’imagerie.
Surrénalectomies
Authors: Valin Isabelle , Rosenberg Dan
Published: February 2023

La surrénalectomie est une intervention qui consiste à retirer une ou les deux surrénales lors de la sécrétion anormale d’une des trois hormones physiologiquement produites par ces glandes. Le diagnostic médical doit permettre de déterminer si la dérive concerne la sécrétion de cortisol (syndrome de Cushing), d’adrénaline (phéochromocytome) ou d’aldostérone (hyperaldostéronisme). Cette détermination médicale permet de préparer l’animal en amont de l’acte chirurgical (trilostane, alpha-bloquants, potassium) pour l’emmener au bloc opératoire dans les meilleures conditions possibles. Le scanner est l’imagerie de choix qui permet de déterminer la faisabilité et les risques chirurgicaux engagés.

L’acte chirurgical consiste en une dissection soignée de la tumeur en épargnant les vaisseaux majeurs et, si possible, en respectant sa capsule. La veine cave caudale est régulièrement embolisée par un thrombus tumoral au travers de la veine phrénico-abdominale qui draine la glande. L’équipe chirurgicale et anesthésique doit être préparée à son extraction par contrôle du débit sanguin dans la veine cave caudale, incision et suture de celle-ci.

Dépassées les complications per- et postopératoires (complications hémorragiques, troubles cardiovasculaires et thrombo-emboliques, pancréatite), la surrénalectomie, quand elle est techniquement possible au moment du diagnostic, est la prise en charge optimum en termes de qualité de vie et de longévité lors de tumeur surrénalienne.
Observation clinique : un cas d’hyperaldostéronisme primairechez un chat
Authors: Chamagne Antoine , Fabrès Virginie , Benchekroun Ghita
Published: February 2023

Un chat British Shorthair mâle castré de 7 ans est présenté pour abattement, dysorexie, PUPD et ventroflexion évoluant de manière fluctuante depuis environ une semaine, sans antécédents médicaux notables. Les examens cliniques et hématobiochimiques d’admission mettent en évidence une hypokaliémie et une densité urinaire diminuée en l’absence d’azotémie, pour un chat par ailleurs normotensif. Les examens d’imagerie (échographie et tomodensitométrie abdominale) font état d’une masse surrénalienne droite sans envahissement locorégional ni atteinte visible d’autres organes. Un dosage d’aldostérone très supérieur aux normes de l’intervalle de référence permet d’établir le diagnostic d’hyperaldostéronisme primaire. Une surrénalectomie droite est réalisée par laparotomie, associée à une lobectomie hépatique partielle au vu de l’adhérence macroscopique notée en chirurgie. L’examen histologique est en faveur d’un corticosurrénalome (ou carcinome surrénalien) métastasé au foie. Le chat présente un très bon état général sans traitement jusqu’à dix-sept mois après la prise en charge chirurgicale, où une récidive clinique et locorégionale du corticosurrénalome est notée. Il est alors décidé d’un traitement médical à base de spironolactone et d’inhibiteur de la tyrosine kinase. Le chat décède trente mois après la surrénalectomie d’une insuffisance cardiaque congestive dans un contexte de cardiomyopathie hypertrophique secondaire à l’hypertension artérielle systémique chronique.
Les affections surrénaliennes chez le furet
Authors: Volait-Rosset Laetitia
Published: February 2023

La maladie surrénalienne est la dysendocrinie la plus fréquente après l’insulinome chez le furet âgé. Elle est provoquée par une production disproportionnée de stéroïdes sexuels causée par une hyperplasie ou une tumeur de la glande surrénale, sous l’effet d’une abondance anormale de gonadotropines.

Les facteurs favorisants de cette maladie endocrinienne sont multifactoriels. La gonadectomie semble être le facteur de risque prépondérant, annihilant le rétrocontrôle négatif des hormones sexuelles gonadiques sur l’axe hypothalamo-hypophysaire. Les patients sont des furets âgés castrés, souvent présentés avec une alopécie symétrique, un retour de l’odeur musquée, un comportement sexuel exacerbé, des troubles uro-génitaux et une perte de poids. La réalisation d’une échographie abdominale peut identifier une adrénomégalie, des modifications structurales de la glande surrénale et des maladies concomitantes. Un bilan hormonal peut aussi révéler une élévation significative des hormones sexuelles.

Le traitement consiste en une approche médico-chirurgicale. L’administration d’agonistes de la GnRH permet de contrôler les signes cliniques tandis que la surrénalectomie constitue le traitement curatif. L’analyse histologique est essentielle pour confirmer la nature tumorale de la glande surrénale. Le pronostic est réservé à sombre et dépend de multiples facteurs. D’autres pathologies d’origine surrénalienne existent chez le furet mais restent rares.
Der Moser-Köfeler-Visualisierungsbogen für die
Handfunktion (MOKÖ)
Authors: Moser Andrea
Published: February 2023

Die österreichischen Ergo- und Handtherapeutinnen Andrea Moser und Eva
Köfeler entwickelten einen Assessmentbogen zur Visualisierung der
Handfunktion. Er leitet Therapeut*innen durch das Assessment und stellt
die Ergebnisse zusammengefasst und farblich dar.
Handtherapie mit Kindern – Besonderheiten und
Möglichkeiten
Authors: Op Heij Donnée
Published: February 2023

Zwischen der Handtherapie mit Erwachsenen und der mit Kindern bestehen viele
Parallelen, aber auch entscheidende Unterschiede. Der Artikel zeigt wesentliche,
praxisrelevante Aspekte in der Behandlung von Kindern mit einer Handverletzung
auf und stellt diese praktisch an einem Fallbeispiel dar.
Frakturen und Luxationen der oberen Extremität beim
Kind
Authors: Söhling Nicolas , Voth Maika , Marzi Ingo
Published: February 2023

Die häufigsten Traumalokalisationen bei Kindern sind der Unterarm und die
Hand. Der Artikel beleuchtet die Diagnostik sowie die konservativen und
operativen Therapiemöglichkeiten bei Verletzungen des
Radiusköpfchens, des Olekranons, des Unterarms und der Hand.
Comparison of bone marrow biopsy and fluorodeoxyglucose-positron emission tomography for the assessment of bone marrow infiltration in children with Hodgkin’s lymphoma
Authors: Arslantaş Esra , Ayçiçek Ali , Akıcı Ferhan , Özkara Selvinaz , Yılmaz Burçak , Özdemir Nihal , Bayram Cengiz
Published: February 2023

Purpose To compare bone marrow biopsy (BMB) with [18F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (PET/CT) imaging in the demonstration of bone marrow involvement in children with Hodgkin’s Lymphoma (HL) and to investigate the effectiveness of PET/CT imaging and thus the necessity for BMB at staging.

Methods Pediatric patients with HL, who underwent both bilateral iliac BMB and PET/CT imaging at disease staging were retrospectively analyzed. In determining bone marrow involvement (BMinv), BMB and/or first/follow-up PET/CT imaging were eligible for review.

Results Fifty-six patients were included. BMinv was detected by PET/CT imaging in 6/56 (10.7%), whereas the proportion was 3/56 (5.3%) in BMB specimens. Bone marrow biopsies and PET/CT images were concordant in 53/56 (94.6%) patients with BMB specimens missing three cases of BMinv detected by PET/CT. When diagnostic accuracy was calculated, sensitivity, specificity, positive predictive value and negative predictive values for PET/CT were 100%, 100%, 100%, 100%, respectively, and the same values for BMB were 50%, 100%, 100%, 94.3%, respectively.

Conclusions The results of PET/CT and BMB for staging of pediatric HL patients were compatible, and PET/CT imaging was found to provide high diagnostic performance in determining BMinv. In keeping with earlier research, the current study showed that BMB may not be necessary in every patient at staging, and should be reserved for cases where PET/CT is inconclusive.