bluuebunny/crossref_metadata_2025 huggingface dataset:
The effect of rehabilitation time on functional recovery after arthroscopic rotator cuff repair: a systematic review and meta-analysis
Authors: Chen Yang , Meng Hui , Li Yuan , Zong Hui , Yu Hongna , Liu HaiBin , Lv Shi , Huai Liang
Published: May 2024

Objective

We compared the effects of early and delayed rehabilitation on the function of patients after rotator cuff repair by meta-analysis to find effective interventions to promote the recovery of shoulder function.

Methods

This meta-analysis was registered in PROSPERO (CRD42023466122). We manually searched the randomized controlled trials (RCTs) in the Cochrane Library, Pubmed, Cochrane Library, EMBASE, the China National Knowledge Infrastructure (CNKI), the China VIP Database (VIP), and the Wanfang Database to evaluate the effect of early and delayed rehabilitation after arthroscopic shoulder cuff surgery on the recovery of shoulder joint function. Review Manager 5.3 software was used to analyze the extracted data. Then, the PEDro scale was employed to appraise the methodological quality of the included research.

Results

This research comprised nine RCTs and 830 patients with rotator cuff injuries. According to the findings of the meta-analysis, there was no discernible difference between the early rehabilitation group and the delayed rehabilitation group at six and twelve months after the surgery in terms of the VAS score, SST score, follow-up rotator cuff healing rate, and the rotator cuff retear rate at the final follow-up. There was no difference in the ASES score between the early and delayed rehabilitation groups six months after the operation. However, although the ASES score in the early rehabilitation group differed significantly from that in the delayed rehabilitation group twelve months after the operation, according to the analysis of the minimal clinically important difference (MCID), the results have no clinical significance.

Conclusions

The improvement in shoulder function following arthroscopic rotator cuff surgery does not differ clinically between early and delayed rehabilitation. When implementing rehabilitation following rotator cuff repair, it is essential to consider the paradoxes surrounding shoulder range of motion and tendon anatomic healing. A program that allows for flexible progression based on the patient’s ability to meet predetermined clinical goals or criteria may be a better option.
Nucleolin myocardial-specific knockout exacerbates glucose metabolism disorder in endotoxemia-induced myocardial injury
Authors: Tang Yuting , Yin Leijing , Yuan Ludong , Lin Xiaofang , Jiang Bimei
Published: May 2024

Background

Sepsis-induced myocardial injury, as one of the important complications of sepsis, can significantly increase the mortality of septic patients. Our previous study found that nucleolin affected mitochondrial function in energy synthesis and had a protective effect on septic cardiomyopathy in mice. During sepsis, glucose metabolism disorders aggravated myocardial injury and had a negative effect on septic patients.

Objectives

We investigated whether nucleolin could regulate glucose metabolism during endotoxemia-induced myocardial injury.

Methods

The study tested whether the nucleolin cardiac-specific knockout in the mice could affect glucose metabolism through untargeted metabolomics, and the results of metabolomics were verified experimentally in H9C2 cells. The ATP content, lactate production, and oxygen consumption rate (OCR) were evaluated.

Results

The metabolomics results suggested that glycolytic products were increased in endotoxemia-induced myocardial injury, and that nucleolin myocardial-specific knockout altered oxidative phosphorylation-related pathways. The experiment data showed that TNF-α combined with LPS stimulation could increase the lactate content and the OCR values by about 25%, and decrease the ATP content by about 25%. However, interference with nucleolin expression could further decrease ATP content and OCR values by about 10–20% and partially increase the lactate level in the presence of TNF-α and LPS. However, nucleolin overexpression had the opposite protective effect, which partially reversed the decrease in ATP content and the increase in lactate level.

Conclusion

Down-regulation of nucleolin can exacerbate glucose metabolism disorders in endotoxemia-induced myocardial injury. Improving glucose metabolism by regulating nucleolin was expected to provide new therapeutic ideas for patients with septic cardiomyopathy.
Folding of a Donor‐Containing Ionene by Intercalation with an Acceptor
Authors: De Swati , Ramakrishnan S.
Published: November 2010

Cationic ionenes that bear electron‐rich 1,5‐dialkoxynaphthalene (DAN) units within the alkylene segment were allowed to interact with different types of electron‐deficient, acceptor‐containing molecules in an effort to realize intercalation‐induced folding of the ionenes; the collapse of the chains was expected to occur in such a way that the donor and acceptor units become arranged in an alternating fashion. Several acceptor‐bearing molecules were prepared by the derivatization of pyromellitic dianhydride and naphthalene tetracarboxylic dianhydride with two different oligoethylene glycol monomethyl ether monoamines. This yielded acceptor molecules with different water solubility and allowed the examination of solvophobic effects in the folding process. UV/Vis spectroscopic studies were carried out by using a 1:1 mixture of the DAN–ionenes and different acceptor molecules in water/DMSO solvent mixtures. The intensity of the charge‐transfer (CT) band was seen to increase with the water content in the solvent mixture, thereby suggesting that the intercalation is indeed aided by solvophobic effects. The naphthalene diimide (NDI) bearing acceptor molecules consistently formed significantly stronger CT complexes when compared to the pyromellitic diimide (PDI) bearing acceptor molecules, which is a reflection of the stronger π‐stacking tendency of the former. AFM studies of drop‐cast films of different ionene–acceptor combinations revealed that compact folded structures are formed most effectively under conditions in which the strongest CT complex is formed.
Global DNA methylation measurement by HPLC using low amounts of DNA
Authors: Armstrong Kelly M. , Bermingham Emma N. , Bassett Shalome A. , Treloar Bryan P. , Roy Nicole C. , Barnett Matthew PG.
Published: November 2010

Epigenetic changes in chromatin structure can influence gene expression without affecting the DNA sequence. The most commonly studied epigenetic modification, DNA methylation, has been implicated in normal tissue development and disease progression, and can be influenced by diet and other environmental factors. Current HPLC methods of determining DNA methylation may require relatively large amounts of DNA (50 μg); as many tissues have low DNA yields, this can be hard to achieve. We isolated DNA from mouse colon and liver in a study investigating post‐natal supplementation with selenium and folic acid. After optimizing the methods to account for lower initial DNA amounts, we digested 3 μg of DNA to deoxynucleotide monophosphates, then purified and quantified it. Samples were analyzed by reversed‐phase HPLC to determine global DNA methylation levels using commercial nucleotide standards. The HPLC column was cooled to 6(C (reducing run time), and detection was at 280 nm (UV). We showed that methylated cytosine can be accurately and reproducibly measured in as little as 3 μg of DNA using this HPLC analysis method (within‐assay CV <2%). We also used this method to detect reduced DNA methylation in liver (P = 0.009) in response to post‐natal supplementation with selenium and folate.
Applying fixed‐priority preemptive scheduling with preemption threshold to asynchronous event handling in the RTSJ
Authors: Kim MinSeong , Wellings Andy
Published: November 2010

The primary goal of asynchronous event handlers (handlers for short) in the Real‐Time Specification for Java (RTSJ) is to have a lightweight concurrency mechanism. The emphasis here is on ‘lightweightness’ which should be achieved by having fewer real‐time threads (servers for short) to execute more handlers. However, it is generally unclear how to efficiently map handlers to servers. In this paper we first define the worst case scenario that demands the least upper bound of servers for self‐suspending and non‐self‐suspending handlers. Based on the worst case scenarios, it is proved that the number of servers required to execute a given number of non‐self‐suspending handlers depends on the number of priority levels, and not on the number of handlers. It is also shown that each self‐suspending handler is required to have its own server to prevent unbounded priority inversion. Based on these results we also propose to adapt the notion of preemption threshold to further minimize the number of priority levels in the system. We have extended the non‐self‐suspending asynchronous event handling (AEH) implementation to support the fixed‐priority scheduling with preemption threshold on an existing RTSJ implementation to show that the number of servers can be further decreased while feasibly scheduling a set of non‐self‐suspending handlers, regardless of the number of the handlers or the priority levels in the system. Copyright © 2010 John Wiley & Sons, Ltd.
Structural Investigation of Coordination Polymers Constructed from a Conformational Bis‐triazole Ligand and V‐Shaped Bridging Carboxylate Anions: Hydrothermal Syntheses, Crystal Structures, and Property Studies
Authors: Ren Chen , Liu Ping , Wang Yao‐Yu , Huang Wen‐Huan , Shi Qi‐Zhen
Published: November 2010

The conformational bis‐triazole ligand 4,4′‐bis[(1,2,4‐triazol‐1‐yl)methyl]biphenyl (btmb, 1), was successfully synthesized, and seven new coordination polymers, namely {M(oba)(btmb)}n [M = Cd2+ (2), Co2+ (3), Ni2+ (4), and Zn2+ (5)], {M(sdba)(btmb)}n [M = Co2+ (6) and Cd2+ (7)], and {[Cu(H2odpa)(btmb)(H2O)]·2H2O}n (8), (H2oba = 4,4′‐oxydibenzoic acid, H2sdba = 4,4′‐sulfonyldibenzoic acid, and H4odpa = 4,4′‐oxydiphthalic acid), have been synthesized by utilizing the btmb ligand and the polymers have been characterized in detail. Complexes 2–4 are isostructural exhibiting 2D‐layer structures and can be described as (3,4)‐connected networks with (42.63.8)(42.6) topological notation. Complex 5 shows 2D layers with left‐ and right‐handed helical chains and has a (3,4)‐connected net with (4.52)(4.53.72) topology. Complexes 6 and 7 are isostructural and display 2D undulating networks with (4,4) sheets that are further packed through van der Waals interactions to generate a 3D supramolecular structure. Complex 8 also represents a 2D network with a 44‐sql net, which is extended into a 3D supramolecular framework by hydrogen‐bonding interactions. The structural differences of these complexes demonstrate that the conformation of the btmb ligand and flexible aromatic polycarboxylate anions play critical roles in the formation of the resulting frameworks. Furthermore, their thermal properties have been studied by thermogravimetric analysis (TGA) and the TGA results reveal that the triazole‐based frameworks have a high thermal stability, which suggests they are good candidates for the construction of more stable complexes. The photoluminescent properties of complexes 2, 5, and 7 have also been studied.
In vitro assessment of osteoblast and macrophage mobility in presence of β‐TCP particles by videomicroscopy
Authors: Beuvelot Johanne , Pascaretti‐Grizon Florence , Filmon Robert , Moreau Marie‐Fraçoise , Baslé Michel F. , Chappard Daniel
Published: November 2010

β‐TCP is widely used to repair bone defects due to its good biocompatibility, macroporosity (favoring bone ingrowth) and bioresorbability. However, cell interactions with the biomaterial at the first times of implantation remain largely unknown. We have observed cell behaviors in direct contact with β‐TCP particles using long‐term culture under videomicroscopy. Osteoblastlike cells (SaOs‐2) and macrophages (J774.2 and mouse peritoneal macrophages) were cultured in the presence of β‐TCP particles. For each experiment, images from 20 independent fields were acquired and stored every 15 min during 8 days. At the end of the culture, they were combined to generate time lapse videos; coverslips were fixed and observed by scanning electron microscopy (SEM). SaOs‐2 proliferation was determined by counting cells on six different and independent fields at days 1, 3, and 6. Videos showed the capacity of cells to displace the particles. Dynamic follow‐up showed active proliferation of SaOs‐2 occurring in the direction of the particles. J774.2 and peritoneal macrophages did not proliferate but came in direct contact with the particles and actively eroded them. SEM showed that cells were stretched and fixed onto the surface and seemed to climb from the coverslip to the particles. The long‐term culture under videomicroscopy allowed a better understanding of the colonization process of β‐TCP particles by osteoblastlike cells and macrophages. Data obtained from long‐term videomicroscopy are in agreement with in vivo observations confirming the interest of β‐TCP to promote osteogenesis. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.
Computational study on the reactions of H2O2 on TiO2 anatase (101) and rutile (110) surfaces
Authors: Huang Wen‐Fei , Raghunath P. , Lin M. C.
Published: November 2010

This study investigates the adsorption and reactions of H2O2 on TiO2 anatase (101) and rutile (110) surfaces by first‐principles calculations based on the density functional theory in conjunction with the projected augmented wave approach, using PW91, PBE, and revPBE functionals. Adsorption mechanisms of H2O2 and its fragments on both surfaces are analyzed. It is found that H2O2, H2O, and HO preferentially adsorb at the Ti5c site, meanwhile HOO, O, and H preferentially adsorb at the (O2c)(Ti5c), (Ti5c)2, and O2c sites, respectively. Potential energy profiles of the adsorption processes on both surfaces have been constructed using the nudged elastic band method. The two restructured surfaces, the 1/3 ML oxygen covered TiO2 and the hydroxylated TiO2, are produced with the H2O2 dehydration and deoxidation, respectively. The formation of main products, H2O(g) and the 1/3 ML oxygen covered TiO2 surface, is exothermic by 2.8 and 5.0 kcal/mol, requiring energy barriers of 0.8 and 1.1 kcal/mol on the rutile (110) and anatase (101) surface, respectively. The rate constants for the H2O2 dehydration processes have been predicted to be 6.65 × 10−27 T4.38 exp(−0.14 kcal mol−1/RT) and 3.18 × 10−23 T5.60 exp(−2.92 kcal mol−1/RT) respectively, in units of cm3 molecule−1 s−1. © 2010 Wiley Periodicals, Inc. J Comput Chem, 2011.
Design of optical cloaks and illusion devices along a circumferential direction in curvilinear coordinates
Authors: Chen Tungyang , Yu Shang-Ru
Published: November 2010

We propose a cloaking and illusion device of circumferential topology based on the concept of transformation optics. The device is capable to cloak an object and/or simultaneously generate illusion images along a circumferential direction in curvilinear orthogonal coordinates. This feature allows us to construct multiple illusions in different ways, irrespective of the profile and direction of incident wave. Particularly when the device is served as a building brick of a larger device, one can generate a circumferential array of illusions in a periodic or any preferred pattern. We demonstrate the effectiveness of the proposed illusion devices by carrying out full wave simulations based on finite element calculations.
Excitational energy transfer enhancing ionization and spatial-temporal evolution of air breakdown with UV laser radiation
Authors: Hummelt Jason S. , Scharer John E.
Published: November 2010

This paper examines the role multiphoton excitation of oxygen has on the ionization of nitrogen in laser air breakdown. Plasma is created by focusing a 193 nm ArF excimer laser using an 18 cm focal length lens, producing a cylindrical 540 μm wide spot of intensity 6.5 GW/cm2, well below the classical limit for collisional cascade (CC) breakdown. By spectroscopically monitoring the B Σ2u+ to X Σ2g+ transition at 391.4 nm of N2+ in N2 and O2 mixes, collisions between N2 and metastable O2 states that have undergone 1+1 absorption processes are shown to lower the degree of nonlinearity (i.e., the number of photons involved in the rate limiting multiphoton absorption process) in the ionization of N2. This process is also found to dominate the 2+1 resonant enhanced multiphoton ionization of N2 in air and be the primary source for ionization of N2 to the B Σ2u+ state. Plasma formation and evolution is also examined using a 1.3 cm focal length objective lens creating a 40 μm wide spot of intensity 1.25 TW/cm2, above the classical limit for breakdown. This plasma is imaged with a fast (1.2 ns) gating intensified charge coupled device camera. Early plasma formation is seen to be inhomogeneous in nature, and significant ion density is found to exist up to 20 μs after the laser pulse.
The fabrication of nanomesas and nanometal contacts by using atomic force microscopy lithography
Authors: Chung Tung-Hsun , Liao Wen-Hsuan , Lin Shih-Yen
Published: November 2010

The influence of preoxidation GaAs surface treatment over the atomic force microscopy-induced local anodic oxidation (LAO) is investigated in this paper. By immerging the GaAs samples into NaOH aqueous solutions, higher nano-oxides with better height distribution could be observed after LAO. The phenomenon is attributed to the hydrophilic surfaces obtained after the treatment such that higher local humidity and uniform water molecular distribution would be obtained on the GaAs surfaces, by using the higher nano-oxides with better height uniformity, nanomesas by using wet chemical etching, and nanometal contact after oxide lift-off are fabricated.
An ARDL model of unrecorded and recorded economies in Turkey
Authors: Dell'Anno Roberto , Halicioglu Ferda
Published: November 2010

Purpose

The goal of this paper is twofold: to estimate the unrecorded economy (UE) of Turkey over the period 1987‐2007 using a revised version of the currency demand approach, and to analyze the relationship between the UE and recorded GDP.

Design/methodology/approach

The paper proposes to measure the UE using the autoregressive distributed lag (ARDL) approach to cointegration analysis. Toda‐Yamamoto causality tests are also conducted to identify the relationship between unrecorded and recorded GDP.

Findings

This research provides fresh evidence of the size of the UE relative to the recorded GDP in Turkey, which ranges from 10.7 percent to 18.9 percent over the estimation period. Moreover, empirical evidence concretely suggests that causality runs from the recorded GDP to the UE. However, there exists a mild reverse causality.

Research limitations/implications

Measures of the UE, and particularly those based on monetary approaches, have been criticized on several counts, including their lack of robustness and weak theoretical foundations (e.g. the velocity of money in the recorded economy and in the UE is the same).

Practical implications

This analysis suggests that the UE is pro‐cyclical with respect to the recorded GDP. It suggests that the phenomenon of the UE is more dangerous when the economy is in an expensive phase. Hence, during a positive business cycle, it is clearly desirable for the government that the anti‐UE controls should be more effective.

Originality/value

The ARDL approach to estimating the size of the UE eliminates the criticism of the previous currency demand estimations, which were based on partial adjustment models. Therefore, the paper's econometric selected cointegration methodology and causality test is an improvement over the existing studies.
Rice bran adhesive modified with potassium permanganate and poly(vinyl alcohol)
Authors: Wang W. , Zhang X. , Li F. , Qi C.
Published: November 2010

Purpose

The purpose of this paper is to develop an environmental adhesive from defatted rice bran (RB) to increase its economic value and provide environmentally friendly products for the wood industry.

Design/methodology/approach

The powder was mixed with water in a flask. After pH adjustment, potassium permanganate (KMnO4) solution was added. Then the mixture was heated in a shaking water bath. After maintaining the mixture at 70°C for 1 h, poly(vinyl alcohol) (PVA) powder was added to the slurry and heated at the same temperature for a further 0.5 h. The adhesive thus prepared was used to bond veneers to evaluate its bonding strength and analysed by IR. The optimised RB adhesive was mixed with phenol formaldehyde resin in a ratio of 8:8 to bond straw particleboard. Silane was used to improve the properties of the straw particleboard.

Findings

As an economically renewable resource, RB has potential use in the preparation of adhesives. When RB powder was treated with KMnO4 and PVA at pH 6, the resulting adhesive was able to produce a bonding strength of 1.29 MPa. Silane was found to be a useful coupling agent in the bonding of straw particleboard. Once the board had been bonded with the mixed adhesive, it was found to have a bending strength of 11.9 MPa and a modulus of elasticity of 2.2 GPa.

Research limitations/implications

Chemical change was not obvious during RB modification, which led to a low water resistance. Further research is needed to modify the method.

Practical implications

RB adhesive was dark in colour, which limits its use for light‐coloured wood. Because of its lower water resistance, this adhesive has to be mixed with other synthetic resins to meet requirements.

Originality/value

A new adhesive product was developed for the wood industry from economic RB. This will contribute to environmentally friendly wood products and the effective utilisation of agricultural residues.
Treatment of focal idiopathic hyperhidrosis with Botulinum Toxin Type A: clinical predictive factors of relapse‐free survival
Authors: Campanati A. , Sandroni L. , Gesuita R. , Giuliano A. , Giuliodori K. , Marconi B. , Ganzetti G. , Offidani A.
Published: November 2010

Background  No material about the identification of predictive clinical factors of therapeutic response to Botulinum Toxin Type A (BTX‐A) in focal idiopathic hyperhidrosis has been found.

Objective  To evaluate if age, sex, extension rate of hyperhidrotic area, localization, disease‐related impairment of life quality, number of previous local, non‐invasive treatments different from BTX‐A, and duration of disease, may affect the relapse‐free survival (RFS) after a BTX‐A treatment in palmar and axillary focal idiopathic hyperhidrosis.

Methods  Forty‐one patients suffering from palmar hyperhidrosis, and 38 patients suffering from axillary hyperhidrosis received intradermal injections of BTX‐A. All patients were clinically screened before and after treatment; they were followed for 15 months after it, according to Hyperhidrosis Disease Severity Scale (HDSS), Minor’s test, and DLQI test, to state disease severity, and disease‐related impairment of quality of life.

Results  The duration of therapeutic effect of BTX‐A is not significantly influenced by age (P = 0.783), sex (P = 0.762), extension of hyperhidrotic area (P = 0.770), site of involvement (P = 0.402), disease‐induced impairment of life quality (P = 0.745), number of previous therapies (P = 0.730), or site of involvement (P = 0.402). In palmar idiopathic hyperhidrosis, patients with a longer disease history show a shorter duration of RFS after a treatment with BTX‐A (P = 0.01).

Conclusions  Patients suffering from palmar hyperhidrosis have a longer lasting disease, and a length of disease more than 20 years in these patients influences the RFS after BTX‐A treatment.
The polymorphism of catalase T/C codon 389 in exon 9 and vitiligo susceptibility: a meta‐analysis
Authors: Lv Y.J. , Liao W.J. , Luan Q. , Wang H. , Wang L. , Li Q.
Published: November 2010

Background  The exact aetiology of vitiligo has not yet been established. Oxidative stress is involved in the pathophysiology of vitiligo. It has been described that some polymorphisms in the catalase (CAT) gene may affect the risk of vitiligo. However, the results were inconsistent.

Objective  We performed a meta‐analysis of the published studies to derive a more precise estimate of the association between CAT T/C at codon 389 in exon 9 polymorphisms and vitiligo risk.

Methods  The PubMed, Medline, Cochrane Library, China National Knowledge Infrastructure (CNKI) databases were searched to identify relevant published studies.

Results  Four case–control studies (cases, 645; controls, 689) that investigated the association between C/T polymorphisms of CAT exon 9 and the risk of vitiligo were retrieved and analysed. Our findings suggested a significant association between the CAT T/C exon 9 polymorphism and vitiligo risk (CT + TT vs. CC pooled odds ratio, 1.43; 95% confidence interval, 1.14–1.80; P = 0 .002).

Conclusion  We found a significant correlation between the CAT T/C exon 9 polymorphism and the risk of vitiligo.
A Randomized Controlled Trial of the Effects of Vitamin D on Muscle Strength and Mobility in Older Women with Vitamin D Insufficiency
Authors: Zhu Kun , Austin Nicole , Devine Amanda , Bruce David , Prince Richard L.
Published: November 2010

OBJECTIVES: To evaluate the effects of vitamin D treatment on muscle strength and mobility in older women with vitamin D insufficiency.

DESIGN: One‐year population‐based, double‐blind, randomized, controlled trial.

SETTING: Perth, Australia (latitude 32°S).

PARTICIPANTS: Three hundred two community‐dwelling ambulant elderly women aged 70 to 90 with a serum 25‐hydroxyvitamin D (25(OH)D) concentration less than 24 ng/mL.

INTERVENTION: Vitamin D2 1,000 IU/d or identical placebo; calcium citrate (1 g calcium/d) in both groups.

MEASUREMENTS: Lower limb muscle strength and mobility as assessed using the Timed Up and Go Test (TUAG).

RESULTS: At baseline, mean±standard deviation serum 25(OH)D was 17.7±4.2 ng/mL; this increased to 24.0±5.6 ng/mL in the vitamin D group after 1 year but remained the same in the placebo group. For hip extensor and adductor strength and TUAG, but not for other muscle groups, a significant interaction between treatment group and baseline values was noted. In those with baseline values in the lowest tertile, vitamin D improved muscle strength and TUAG more than calcium alone (mean (standard error): hip extensors 22.6% (9.5%); hip adductors 13.5% (6.7%), TUAG 17.5% (7.6%), P<.05). Baseline 25(OH)D levels did not influence patient response to supplementation.

CONCLUSION: Vitamin D therapy was observed to increase muscle function in those who were the weakest and slowest at baseline. Vitamin D should be given to people with insufficiency or deficiency to improve muscle strength and mobility.
Functional magnetic resonance imaging studies of acupuncture mechanisms: a critique
Authors: Beissner Florian
Published: November 2010

Functional magnetic resonance imaging has been used extensively to study the underlying mechanisms of acupuncture. More than 80 studies and a dozen review articles have been published on this topic in the past 10 years. Emphasising the statistical quality of the studies, this critical review evaluates the results obtained so far by studies that have used a hypothesis‐driven approach. A minimum sample size of 12 subjects, the application of random effects (or mixed effects) analyses, and a threshold corrected for multiple comparisons were defined as inclusion criteria for a meta‐analysis of the reported cortical activations. Fourteen out of 71 studies met the inclusion criteria. The majority of these studies reported activations in cortical areas relevant to the processing of somatosensory, motor, or pain signals, as well as areas related to the special senses. From this type of study, it is so far impossible to say if cortical activations under acupuncture are part of an underlying mechanism, or if they simply reflect the brain's processing of the somatosensory or pain stimulus from the acupuncture needle stimulation. In the future, the application of data‐driven methods may lead to a more comprehensive understanding of neuronally mediated acupuncture effects.
The Limits of the Explanatory Power of Developmentalism
Authors: Sobel David
Published: November 2010

Richard Kraut's neo-Aristotelian account of well-being, Developmentalism, aspires to explain not only which things are good for us but why those things are good for us. The key move in attempting to make good on this second aspiration involves his claim that our ordinary intuitions about what is good for a person can be successfully explained and systematized by the idea that what benefi ts a living thing develops properly that living thing's potentialities, capacities, and faculties. I argue that Kraut's understanding of such proper development plays no serious constraining role in shaping the details of the account. If this is correct, Developmentalism lacks the potential to explain or vindicate the intuitions about what is good for us that it champions. In effect, Kraut offers us a list of things that he claims benefits a person, but he lacks a theory of what those things have in common such that they benefit him.
Use of the CD19 count in a primary care laboratory as a screening method for B-cell chronic lymphoproliferative disorders in asymptomatic patients with lymphocytosis
Authors: te Raa G. Doreen , Fischer Kathelijn , Verweij Wim , van Houte Arend J. , Kater Arnon P. , Biesma Douwe H.
Published: November 2010

Background: Detection of absolute and relative lymphocytosis in otherwise asymptomatic elderly patients is very common in the primary care setting and frequently results in referral for screening of lymphoproliferative disorders. Since many B-cell chronic lymphoproliferative disorders (B-CLPD) are indeed asymptomatic at diagnosis in most patients with lymphocytosis, no sign of such a disorder is usually detected. Currently, specific guidelines for screening of patients with lymphocytosis are lacking. We investigated the practicability and clinical value of a single colour CD19 count performed by a primary care laboratory in order to improve the diagnostic follow-up of patients with lymphocytosis in a primary care laboratory.

Methods: The capability of detecting monoclonal B-cell lymphocytosis and B-CLPD by CD19, was first confirmed in patient samples with known B-CLPD. Next, in a previously defined geographic area, a CD19 count was performed on all samples for patients aged ≥40 years with relative or absolute lymphocytosis but without neutropenia. Clinical follow-up, with a median of 4 years, was performed using both a survey among the requesting general practitioners and by analysis of the records of the referral hospitals within the borders of the defined area.

Results: A total of 520 cases with asymptomatic lymphocytosis were identified. In all cases, the CD19 count was performed; 207 (40%) showed increased values and 313 (60%) showed normal values. An increase in CD19 proved highly sensitive for detection of B-CLPD (98%, 95% CI; 94%–100%) with a high positive predictive value (57%, 95% CI; 50%–63%). The area under curve, the receiver-operating characteristic curve of the CD19 count (0.93, 95% CI; 0.91–0.96), was significantly higher compared to the absolute lymphocyte count (0.86, 95% CI; 0.83–0.89), especially in patients with moderate lymphocytosis.

Conclusions: This study indicates that the CD19 count, performed by a primary care laboratory, is feasible and a promising tool for initial screening of lymphocytosis to discriminate B-CLPD from benign causes of lymphocytosis.
ChemInform Abstract: Thermodynamic and Kinetic Destabilization in LiBH4/Mg2NiH4: Promise for Borohydride‐Based Hydrogen Storage.
Authors: Vajo John J. , Li Wen , Liu Ping
Published: November 2010

The title system displays both thermodynamic and kinetic destabilization.
ChemInform Abstract: Bismuth(III) Triflate Catalyzed Allylation of Cyclic Acetals and Dithianes Followed by in situ Derivatization to Generate Highly Functionalized Esters.
Authors: Krabbe Scott W. , Spafford Matthew J. , Mohan Ram S.
Published: November 2010

A robust catalytic method for the allylation of cyclic acetals is reported.
ChemInform Abstract: Polyether‐Substituted Thiazolium Ionic Liquid Catalysts — A Thermoregulated Phase‐Separable Catalysis System for the Stetter Reaction.
Authors: Yu Fengli , Zhang Ruili , Xie Congxia , Yu Shitao
Published: November 2010

A new type of thermoregulated thiazolium ionic liquid catalyst for the Stetter reaction is synthesized by introducing a polyether chain to the thiazole.
ChemInform Abstract: Highly Recyclable, Imidazolium Derived Ionic Liquids of Low Antimicrobial and Antifungal Toxicity: A New Strategy for Acid Catalysis.
Authors: Myles Lauren , Gore Rohitkumar , Spulak Marcel , Gathergood Nicholas , Connon Stephen J.
Published: November 2010

Imidazolium derived ionic liquid catalysts are developed which are aprotic, but can act as Broensted acidic catalysts in the presence of protic additives.
ChemInform Abstract: Synthesis of Dithiocarbamate by Markovnikov Addition Reaction in Aqueous Medium.
Authors: Halimehjani Azim Ziyaei , Marjani Katayoun , Ashouri Akram
Published: November 2010

The one‐pot three‐component reactions of amines (II), CS2 (III) with vinyl ethers (I) and (V) via Markovnikov addition affords dithiocarbamates (IV) and (VI) in high yields, complete regiospecificity and by an environmentally benign procedure.
ChemInform Abstract: KF‐Alumina‐Mediated Bargellini Reaction
Authors: Rohman Md. Rumum , Myrboh Bekington
Published: November 2010

of anilines, phenols and thiophenols with cyclic ketones
ChemInform Abstract: A Practical Route for the Preparation of Aromatic trans‐β‐Nitroolefins
Authors: Groszek G.
Published: November 2010

via an effective variation of the Henry condensation
ChemInform Abstract: Preparation of Anionic Phosphine Ligands in situ for the Palladium‐Catalyzed Buchwald/Hartwig Amination Reactions of Aryl Halides.
Authors: Yu Guang‐Ao , et al. et al.
Published: November 2010

A wide range of (het)aryl halides smoothly undergoes Hartwig—Buchwald amination with aromatic and aliphatic amines in the presence of a novel Pd—phenylindenylphosphine complex.
ChemInform Abstract: Environmentally Friendly Methods for Syntheses of New Aromatic Bisesters.
Authors: Zbancioc Gheorghita N. , Zbancioc Ana Maria V. , Mangalagiu Ionel I.
Published: November 2010

A solvent‐free microwave‐assisted synthesis of bisesters (III) is less efficient.
ChemInform Abstract: Synthesis of 3‐Benzoyl Acrylates/Acrylamides via Dehydrogenation of 3‐Benzoyl Propionates/Propionamides Using IBX/p‐TsOH.
Authors: Li Ziyuan , Wang Yiyun , Tang Changhua , Xu Jinyi , Wu Xiaoming , Yao Hequan
Published: November 2010

The reaction conditions are optimized.
ChemInform Abstract: An E‐Factor Minimized Protocol for the Preparation of Methyl β‐Hydroxy Esters.
Authors: Fringuelli Francesco , Lanari Daniela , Pizzo Ferdinando , Vaccaro Luigi
Published: November 2010

The optimization of the preparation of title compounds (III) by a solvent‐free aldol reaction of aryl aldehydes (I) with enol ether (II) followed by desilylation is reported.
ChemInform Abstract: Efficient Preparation of Isothiocyanates from Dithiocarbamates Using Bromineless Brominating Reagent.
Authors: Yella Ramesh , Ghosh Harisadhan , Murru Siva , Sahoo Santosh K. , Patel Bhisma K.
Published: November 2010

1,1′‐(Ethane‐1,2‐diyl)dipyridinium bistribromide (EDPBT) is used as easily accessible reagent for the direct conversion of dithiocarbamates into isothiocyanates.
ChemInform Abstract: Immobilization of Pd on Nanosilica Dendrimer as SILC: Highly Active and Sustainable Cluster Catalyst for Suzuki—Miyaura Reaction.
Authors: Hagiwara Hisahiro , Sasaki Hirokazu , Tsubokawa Norio , Hoshi Takashi , Suzuki Toshio , Tsuda Tetsuya , Kuwabata Susumu
Published: November 2010

The reusable catalyst is found to be effective for coupling reactions of aryl bromides and triflates and allows the preparation of ortho‐substituted biaryls under mild conditions.
ChemInform Abstract: A Green and Novel Method of Synthesizing 2,2′‐Arylmethylene Bis(3‐hydroxy‐5,5‐dimethylcyclohex‐2‐enone) Catalyzed by L‐Histidine in Ionic Liquid.
Authors: Zhang Yan , Shang Zhicai
Published: November 2010

The system L‐His / ionic liquid can be recycled several times with no decrease in yield or rate.
ChemInform Abstract: Synthesis of 2,4,5‐Substituted Oxazoles from 2‐Hydroxyaromatic Aldehydes.
Authors: Gavrilova N. A. , Pozhil'tsova O. S. , Semichenko E. S. , Suboch G. A.
Published: November 2010

A two‐step procedure leads via stable oxazolium salt intermediates to novel oxazoles (III).
ChemInform Abstract: Catalytic and Efficient Oxidation of Urazole Derivatives to Their Corresponding Triazolinediones Using Ammonium Nitrate and Metal Hydrogen Sulfate as Catalyst.
Authors: Ghorbani‐Chogamarani Arash , Zeinivand Javad , Mallakpour Shadpour
Published: November 2010

Advantages are high selectivity, cost‐efficiency, and easy work‐up.
ChemInform Abstract: Reactions of 3‐Amino‐1,2,4‐triazoles with Cinnamic Aldehydes
Authors: Lipson V. V. , Karnozhitskaya T. M. , Shishkina S. V. , Shishkin O. V. , Turov A. V.
Published: November 2010

formation of Schiff bases (III) and/or triazolopyrimidines (IV) depending on the reaction conditions
ChemInform Abstract: One‐Pot Three‐Component Access to Pyranocyclopentendiones.
Authors: Teimouri Mohammad Bagher , Mansouri Farideh
Published: November 2010

Isocyanides, dialkyl acetylenedicarboxylates and 3,5‐diphenylcyclopentane‐1,2,4‐trione undergo smooth condensation reaction to afford title compounds, e.g. (IV), under mild reaction conditions.
ChemInform Abstract: An Efficient Synthesis of Oxa‐ and Aza‐Condensed Tetrahydropyridines from Cyclic Enones.
Authors: Zanatta Nilo , da Fernandes Liana S. , Muenchen Sinara , Coelho Helena S. , Amaral Simone S. , Fantinel Leonardo , Bonacorso Helio G. , Martins Marcos A. P.
Published: November 2010

The reaction of cyclic enones (I) with diamines or amino alcohols affords the products with high purity in good to excellent yields.
ChemInform Abstract: Pyrrolo[1,2‐a]quinoline Derivatives via 1,3‐Dipolar Cycloaddition of Quinolinium N‐Ylides.
Authors: Georgescu Emilian , Dumitrascu Florea , Georgescu Florentina , Draghici Constantin , Popa Marcel M.
Published: November 2010

The title compounds (IV) are synthesized by 1,3‐dipolar cycloaddition of in situ generated quinolinium N‐ylides with ethyl propiolate.
ChemInform Abstract: Synthesis and Biological Evaluation of Novel Benzodioxinocarbazoles (BDCZs) as Potential Anticancer Agents.
Authors: Ayerbe Nathalie , Routier Sylvain , Gillaizeau Isabelle , Maiereanu Carmen , Caignard Daniel‐Henry , Pierre Alain , Leonce Stephane , Coudert Gerard
Published: November 2010

The synthetic strategy consists of a palladium‐catalyzed Stille cross‐coupling reaction to (III) followed by photochemically induced 6π‐electrocyclization.
ChemInform Abstract: Preparation of Pyrimidine‐N‐oxides by Condensation of Functionalized Enamides with Hydroxylamine Hydrochloride.
Authors: Zimmer Reinhold , Lechel Tilman , Rancan Giaime , Bera Mrinal K. , Reissig Hans‐Ulrich
Published: November 2010

Reaction of enamides (I) with hydroxylamine hydrochloride proceeds under mild conditions to give the expected pyrimidine N‐oxides.
ChemInform Abstract: Microwave‐Assisted Synthesis of 4‐Amino‐2‐arylthieno[2,3‐d]pyrimidines and Their Subsequent Functionalization.
Authors: Chen Binbin , Perspicace Enrico , Hesse Stephanie , Kirsch Gilbert
Published: November 2010

Coupling of 2‐amino‐3‐cyanothiophenes with aromatic nitriles affords the title skeleton.
ChemInform Abstract: Intramolecular Heterocyclization of N‐(Pyrimidin‐2‐yl)imines of Methyl Trifluoropyruvate.
Authors: Sokolov V. B. , Aksinenko A. Yu.
Published: November 2010

The title reaction affords 3‐fluoroimidazopyrimidinecarboxylates (IV).
ChemInform Abstract: The Mannich Reaction in the Synthesis of N,S‐Containing Heterocycles. Part 9. A New Approach to Thieno[2,3‐d]pyrimidines
Authors: Dotsenko V. V. , Krivokolysko S. G. , Litvinov V. P.
Published: November 2010

via three‐component reaction of 2‐amino‐3‐cyanodihydrothiophene (I) with p‐toluidine and formaldehyde
ChemInform Abstract: Reaction of 1‐Amino Bisphosphinic Acids with Acid Chlorides: Synthesis of Novel Cyclic 1‐Hydroxy‐1′‐amino‐1,1‐bisphosphinic Acids.
Authors: Kaboudin Babak , Saadati Fariba , Yokomatsu Tsutomu
Published: November 2010

Aminobisphosphinic acid (I) is activated by silylation with hexamethyldisilazane and subsequently treated with acid chlorides to give cyclic bisphosphinic acids (III).
ChemInform Abstract: Preparation of Dialkyl 1‐(Alkylamino)alkylphosphonates, Alkyl [1‐(Alkylamino)alkyl]phenylphosphinates and [1‐(Alkylamino)alkyl]diphenylphosphine Oxides via “in situ” Generated Iminium Ions.
Authors: Goldeman Waldemar , Soroka Miroslaw
Published: November 2010

The iminium ions react with phosphite (II), phosphonite (IV), and phosphinite (XI) to give the title compounds in good to excellent yields.
ChemInform Abstract: Synthesis of Cycloalkenyl Geminal Bisphosphonates by Ring Closing Metathesis.
Authors: Mohamed Salimo , Charmasson Yolande , Attolini Mireille , Maffei Michel
Published: November 2010

Five‐ and six‐membered cycloalkenyl bisphosphonates (II) and (VI) are synthesized by ring closing metathesis in the presence of ruthenium alkylidene catalysts.
ChemInform Abstract: Synthesis of Antimicrobial Natural Products Targeting FtsZ: (+)‐Totarol (Ia) and Related Totarane Diterpenes.
Authors: Kim Michelle B. , Shaw Jared T.
Published: November 2010

The approach renders possible the preparation of title compound (Ia), totaradiol (Ib) and totarolone (Ic), which exhibit a comparable inhibition of the bacterial cell division protein.
ChemInform Abstract: Synthesis of the Guaianolide Ring System via Cycloaddition of a Bicyclic Carbonyl Ylide with Allyl Propiolate.
Authors: Navickas Vaidotas , Ushakov Dmitry B. , Maier Martin E. , Stroebele Markus , Meyer H.‐Juergen
Published: November 2010

The ester (I), readily available in 5 steps from (‐)‐carvone, is used as starting material in the sequence.
ChemInform Abstract: New Dammarane Saponins from the Steamed Ginseng Leaves
Authors: Tung Nguyen Huu , Song Gyu Yong , Kang Hee‐Kyoung , Kim Young Ho
Published: November 2010

isolation, structure and cytotoxicity of two new dammarane‐type saponins, ginsenosides ST1 (Ia) and ST2 (Ib)
ChemInform Abstract: Total Synthesis of Syringolin A.
Authors: Dai Chunhui , Stephenson Corey R. J.
Published: November 2010

The α,β‐unsaturated ester (I) is prepared starting from L‐valine and the unnatural 3,4‐dehydrolysine fragment (II) starting from Garner′s aldehyde.
ChemInform Abstract: One Step Synthesis of Biotinylated Amino Acids.
Authors: Feng Siliang , Li Senhao , Kang Xiaoyu , Liu Keliang
Published: November 2010

The rapid preparation of biotinylated amino acids (III), (V), and (VII) is achieved by using a combination of biotin (II), HBTU, and DIEA as coupling reagents.
ChemInform Abstract: β‐Selective C‐Mannosylation of Electron‐Rich Phenols.
Authors: Weck Stefan , Opatz Till
Published: November 2010

The reaction of imidate (I) with phenols in the presence of TmsOTf results in exclusive formation of aryl β‐C‐glycosides.
ChemInform Abstract: Convenient Synthesis of D‐Talose from D‐Galactose.
Authors: Xiao Hualing , Wang Guangfa , Wang Peng , Li Yingxia
Published: November 2010

The rare and expensive D‐talose (V) is conveniently synthesized from readily available β‐D‐galactose pentaacetate (I).
ChemInform Abstract: One‐Pot Synthesis of Azanucleosides from Proline Derivatives. Stereoselectivity in Sequential Processes.
Authors: Boto Alicia , Hernandez Dacil , Hernandez Rosendo
Published: November 2010

Title synthesis of azanucleosides includes a sequential radical decarboxylation—oxidation—nucleophilic addition reaction.
ChemInform Abstract: Molten Salt Synthesis, Characterization and Luminescence of ZnWO4:Eu3+ Nanophosphorus.
Authors: Yan Bing , Lei Fang
Published: November 2010

The red nanophosphor of title is synthesized by addition of molten MNO3 (M: Li, Na, K) to an aqueous solution of Zn(NO3)2, Eu(NO3)2, and Na2WO4.
ChemInform Abstract: One‐ and Two‐Dimensional Inorganic Crystals Inside Inorganic Nanotubes
Authors: Hong Sung You , Kreizman Ronen , Rosentsveig Rita , Zak Alla , Sloan Jeremy , Enyashin Andrey N. , Seifert Gotthard , Green Malcolm L. H. , Tenne Reshef
Published: November 2010

Review: 74 refs.
ChemInform Abstract: Inorganic Analogues of Graphene
Authors: Rao C. N. R. , Nag Angshuman
Published: November 2010

Review: MoS2, WS2, BN or BCN; 50 refs.
ChemInform Abstract: Silicon Nanowires — Synthesis, Properties, and Applications
Authors: Shao Mingwang , Ma Dorthy Duo Duo , Lee Shuit‐Tong
Published: November 2010

Review: 172 refs.
ChemInform Abstract: Controlled Growth of Inorganic Nanocrystals: Size and Surface Effects of Nuclei
Authors: Shen Shuling , Wang Xun
Published: November 2010

Review: 85 refs.
ChemInform Abstract: Nanoparticles as Semi‐Heterogeneous Catalyst Supports
Authors: Schaetz Alexander , Reiser Oliver , Stark Wendelin J.
Published: November 2010

Review: [96 refs.]
ChemInform Abstract: The Chemical and Biological Properties of Protopine and Allocryptopine
Authors: Vacek Jan , Walterova Daniela , Vrublova Eva , Simanek Vilim
Published: November 2010

Review: 97 refs.
ChemInform Abstract: Palladium Catalysis Using Dendrimers: Molecular Catalysts versus Nanoparticles
Authors: Astruc Didier
Published: November 2010

Review: 139 refs.
ChemInform Abstract: Recent Progress in Homogeneous Supported Asymmetric Catalysis: Example of the BINAP and the BOX Ligands
Authors: Framery Eric , Andrioletti Bruno , Lemaire Marc
Published: November 2010

Review: 61 refs.
ChemInform Abstract: An Approach Based on Organic Synthesis Toward Elucidating the Mechanism of Super Energy Transfer Efficiencies of Peridinin in Photosynthesis
Authors: Kajikawa Takayuki , Furuichi Noriyuki , Katsumura Shigeo
Published: November 2010

Review: about 50 refs.
ChemInform Abstract: Solution Stability and Thermal Degradation of Some Cyclic Dithiocarbamates
Authors: de Cassia da Silva Rita , Cavalheiro Eder Tadeu Gomes , Chierice Gilberto Orivaldo
Published: November 2010

Review: 43 refs.
ChemInform Abstract: Stimulus Responsive Peptide Based Materials
Authors: Loewik Dennis W. P. M. , Leunissen E. H. P. , van den Heuvel M. , Hansen M. B. , van Hest Jan C. M.
Published: November 2010

Review: 71 refs.
Robust H∞ disturbance attenuation for uncertain systems with time‐varying delay
Authors: Yoneyama Jun
Published: November 2010

This paper discusses robust H∞ disturbance attenuation for an uncertain system with time‐varying delay. An appropriate Lyapunov functional, which takes into account the range of time‐delay and its derivative, is introduced to investigate robust H∞ disturbance attenuation. Less conservative results are obtained by such a Lyapunov functional with model transformation method and free weighting matrix method. Numerical examples are given to show the effectiveness of the proposed method. © 2010 Wiley Periodicals, Inc. Electron Comm Jpn, 93(12): 44–49, 2010; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/ecj.10178