bluuebunny/crossref_metadata_2025 huggingface dataset:
OMICs Technologies for Natural Compounds-based Drug Development
Authors: Aborode Abdullahi Tunde , Awuah Wireko Andrew , Mikhailova Tatiana , Abdul- Rahman Toufik , Pavlock Samantha , Kundu Mrinmoy , Yarlagadda Rohan , Pustake Manas , Correia Inês Filipa da Silva , Mehmood Qasim , Shah Parth , Mehta Aashna , Ahmad Shahzaib , Asekun Abiola , Nansubuga Esther Patience , Amaka Shekinah Obinna , Shkodina Anastasiia Dmytrivna , Alexiou Athanasios
Published: July 2022

Compounds isolated from natural sources have been used for medicinal purposes for
many centuries. Some metabolites of plants and microorganisms possess properties that would
make them effective treatments against bacterial infection, inflammation, cancer, and an array of
other medical conditions. In addition, natural compounds offer therapeutic approaches with lower
toxicity compared to most synthetic analogues. However, it is challenging to identify and isolate potential
drug candidates without specific information about structural specificity and limited
knowledge of any specific physiological pathways in which they are involved. To solve this problem
and find a way to efficiently utilize natural sources for the screening of compounds candidates,
technologies, such as next-generation sequencing, bioinformatics techniques, and molecular analysis
systems, should be adapted for screening many chemical compounds. Molecular techniques capable
of performing analysis of large datasets, such as whole-genome sequencing and cellular protein
expression profile, have become essential tools in drug discovery. OMICs, as genomics, proteomics,
and metabolomics, are often used in targeted drug discovery, isolation, and characterization.
This review summarizes technologies that are effective in natural source drug discovery and aid in a
more precisely targeted pharmaceutical approach, including RNA interference or CRISPR technology.
We strongly suggest that a multidisciplinary effort utilizing novel molecular tools to identify
and isolate active compounds applicable for future drug discovery and production must be enhanced
with all the available computational tools.
Decomposition Kinetics of 1,1-Dihydroperoxycyclohexane in Some Organic
Solvents
Authors: Grabovskii Stanislav A. , Andriyashina Nadezhda M. , Safiullin Rustam L.
Published: July 2022

Background:

1,1-Bishydroperoxides are used as oxidizing agents, radical initiators, in addition,
studies of biological activity show the promise of this area of research.

Objective:

There are currently no kinetic data on the thermal stability of these peroxides in various solvents.
Therefore, we investigated the thermal stability of 1,1-dihydroperoxycyclohexane as the most
widely used at present.

Methods:

The rate constants and activation parameters were measured at the temperature range of 100-
170oC in the presence of 2-naphthol, which inhibits the induced decomposition of the peroxide by free
radicals. Peroxide concentration was determined by iodometric method.

Results:

The rate constants of the reaction with the solvents and of the monomolecular decomposition
of the peroxide were determined.

Conclusion:

The use of DHPC as a radical initiator requires taking into account its reactions with the
solvent and/or monomer, in addition to its monomolecular decomposition with the formation of free
radicals.
Do Quercetin and Vitamin E Properties Preclude Doxorubicin-induced
Stress and Inflammation in Reproductive Tissues?
Authors: Zal Fatemeh , Samare-Najaf Mohammad , Jamali Navid , Vakili Sina , Khodabandeh Zahra
Published: July 2022

Background:

In recent decades, the exposure to doxorubicin (DOX) has elevated due to the increment in the incidence of cancer, especially among the young population, which, despite the desired restorative impacts, threatened the quality of life of survivors, particularly concerning their reproductive ability.

Objectives:

Although previous studies have shown the effectiveness of quercetin (QCT) and vitamin E (Vit.E), two major dietary antioxidants with favorable attributes regarding the female reproductive system, on doxorubicin-induced insulting to the ovary and uterus. The mechanisms involved in responding to stress and inflammation have not been elucidated. Hence, this study sought to evaluate the preventive effects of these two antioxidants on doxorubicin-induced disruption of ovarian and uterine stress and inflammation.

Methods:

The study involved 48 female rats that were equally allocated into 6 groups as control (CON), QCT (20mg/Kg), Vit.E (200mg/Kg), DOX (accumulative 15mg/Kg), DOX+QCT, and DOX+Vit.E. Upon 21 days treatment, the activity of Superoxide Dismutase (SOD), Catalase (CAT), Glutathione-dependent system, Total Antioxidant Capacity (1), Malondialdehyde (MDA), Nitric Oxide (NO), and Tumor Necrosis Factor-alpha (TNF-#945;&in the reproductive tissues and serum were evaluated.

Results:

Findings demonstrated that the levels of CAT, SOD, Glutathione Peroxidase (GPx), and TAC were alleviated by the studied antioxidants in both tissues (p-value<0.05). Furthermore, both supplements revealed ameliorative effects on DOX-induced alterations in NO, MDA (p-value<0.001), and TNF-αlevels.

Conclusion:

Taking together, the present findings suggested the promising alleviative properties of QCT and Vit.E via modulating stress- and inflammation-responsive mechanisms against DOX-induced female reproductive toxicity.
Developing a Gagne theory-based learning video for thematic subject in elementary school
Authors: Putra I Gede Widiartana , Warpala I Wayan Sukra , Sudatha I Gde Wawan , Utami Ni Putu Rara Stianing
Published: July 2022

The COVID-19 has shown many significant impacts in life such as in educational field which required students and teachers to conduct a blended learning using creative learning media. It should be able to make the students learning independently. However, that was not an easy thing since the teacher only used a conventional learning media: lecturing and textbook. To solve it, this research aimed to design learning media which focused on Tematic Subjects from Indonesian curicculum of 2013. The development was focused on Science subject only. The development model used ADDIE model and implemented Gagne's 9 steps/events of learning theory. The results of the research found that (1) design of Science learning video with the ADDIE model, (2) Science learning video is valid with resulted: good predicate (80.4%) on expert review of the subject matters, very good predicate (97, 7%) on expert review of the Science learning video media, very good predicate (94.1%) on learning design expert review, very good predicate (93.76%) on individual test, very good predicate (92.61%) on small group test, and  very good predicate (90.45%) on field test. Importantly, (3) the effectiveness of development concluded that there was a significant difference between the results of pretest and posttest.
Effect of Oil Carbon Chain Length on the Physical Stability and Bioactivity of Nanoemulsion Delivery Systems Incorporating Lipophilic Ingredients
Authors:   University of Massachusetts, Amherst, Guo Xin , Chang Ming ,   jiangna university
Published: July 2022

In the nanoemulsion-related research, enough studies have concentrated on the effect of oil types, especially oil carbon chain length, on the bioavailability of the phytochemicals. However, there is still a lack of systematical research on the effect of oil carbon chain length influencing whole delivery system, especially for bioactivity evaluation. Herein, the overall aim of this study was to test the effect of oil carbon chain length on the physical stability and bioactivity of the designed nanoemulision system. The emulsion had good physical stability during the incubation time, but no significant differences were detected in the physical stability among different treated groups. The best bioactivity (lipid-lowering effect, in vivo antioxidant activity) of tocopherol and sesamol was in the palm oil (long carbon chain length) group.Overall, this data is meaningful for underlying applications of designed system in lipophilic ingredients delivery.*Xin Guo, Biotechnology Division Student Award Winner*
Effects of Growth Conditions on the Bacterial Conversion of Methane to Lipids
Authors:   University of Louisiana at Lafayette, Dizon Lisa Stephanie , Bertrand Robert S. ,   University of Louisiana at Lafayette, Zappi Mark ,   University of Louisiana at Lafayette, Hernandez Rafael ,   University of Louisiana at Lafayette, Holmes William ,   University of Louisiana at Lafayette, Fortela Dhan Lord ,   University of Louisiana At Lafayette, Revellame Emmanuel ,   University of Louisiana At Lafayette
Published: July 2022

The huge decline in natural gas prices led to an increase in flaring which embodies wasted product, lost energy, lost revenues, and major greenhouse gas emission (GHG). Methane is a major component of natural gas that could be diverted as microbial substrate for the production of valuable products. Methanotrophs are gaining interests due to their ability to utilize CH4 as its sole carbon and energy source to produce a wide variety of bio-products such as lipids, carbohydrates, fuels and power, biomolecules, proteins and renewable chemicals. The lipids derived from the intracellular membrane of methanotrophs are vital precursors for the production of biodiesel and human health supplements. This study aimed to establish the growth conditions of methanotrophs that maximize methane consumption and lipid production. Growth parameters were varied to study the effects of media (nitrate mineral salts (NMS) and synthetic wastewater (SW)), pH (4.0 and 6.8) and CH4 to air ratio (1:1 and 1:4) on the bacterial conversion of methane to lipids. A multi-level categoric design of experiment was employed to verify the most suitable conditions for CH4 consumption and lipid production. Methane consumption was monitored via gas chromatography analysis of the headspace gases. Full length 16S rRNA gene diversity analysis was done to identify the species present in the consortium and to determine the changes in their relative abundance. After 18 days of incubation, results show that the highest CH4 consumption was 6.62% with a lipid yield of 6.93% that can be achieved using SW medium, at pH=6.8, and CH4 to air ratio of 1:1. Thus, this research provides new insights on the potential of natural microbial consortium to convert CH4 into lipids that could address concerns on greenhouse gas emission reduction as well as for value-added resources recovery.
Thoughtful Optimization of Microwave-assisted Saponification and Extraction of MOSH&MOAH in Edible Oil
Authors:   University of Liege, Bauwens Grégory , Purcaro Giorgia ,   University of Liege
Published: July 2022

The analysis of mineral oil hydrocarbons (MOH) in food is a challenging task, mainly due to the high complexity of the matrices and the high affinity of mineral oil with the lipid fraction and its components. The sample preparation step represents a critical point as both time-consuming and prone to recovery loss. Nevertheless, even when dealing with edible oils it is indispensable to enrich the fraction of interest and remove potential interferences.The aim of this work is to improve the throughput of the enrichment step by performing a single step microwave-assisted extraction and saponification (MASE). The choice of the conditions and the solvents have been carefully studied to maximize the yield, the saponification efficiency, and avoid bias due to the different partition of the internal standards (ISs) in the different phases. The mixture of ethanol/water (1:1) showed the best performances in terms of saponification efficiency and ISs partition and it has been studied further to evaluate the effective extraction yield for MOSH and MOAH spiking different edible fats (coconut oil, sunflower oil, extra virgin olive oil and palm oil). The analysis well all performed exploiting the highly informative LC-GC×GC-TOFMS/FID platform.
Lignin-alginate-based Biopolymers for the Bioencapsulation of Rhizobium
Authors:   University of Kentucky, Adjuik Toby A. , Nokes Sue E. ,   University of Kentucky, Montross Michael D. ,   University of Kentucky
Published: July 2022

Cell immobilization provides a physical protection for viable Rhizobial cells in a confined carrier material allowing for the cells’ slow release into the environment. While several petroleum-based polymers have been tested for encapsulating microbes, they are often less biodegradable in the environment and may adversely affect viability of cells. One material that is biobased and has been underutilized for Rhizobium cell carriers is lignin. The present study was conducted to evaluate the feasibility of using lignin-alginate biopolymers with a starch additive to bioencapsulate and release Rhizobium cells.Rhizobium cells were bioencapsulated into the lignin-alginate starch beads and their efficiency i.e [(log of number of cells in wet beads/log of number of cells in solution matrix) x 100%] and release kinetics were determined. Light microscopy and scanning electron microscopy were also used to investigate the surface morphology of the beads. Our results show that all variations (alginate, lignin-alginate, and lignin-alginate with starch additive) of the wet bioencapsulated beads achieved a similar efficiency 97%. However, the presence of starch in the lignin-alginate beads increased the survival of Rhizobium cells after drying from 61 to 84% compared to only alginate encapsulation. These results imply that lignin, a readily available biopolymer is a potential component for the manufacture of carrier materials for encapsulating Rhizobium cells.
Vlaamse Sovjets aan de IJzer? Leven en werken van Antoon Pira (1887-1939): het einden van een mythe
Authors: Clijsters Edi , Govaerts Bert
Published: July 2022

Antoon Pira (1887-1939) is sinds 1968 (toen een eerste korte biografische schets over hem verscheen) een bekende naam in de historiografie van de Frontbeweging. Hij wordt vaak vermeld als een radikale randfiguur, flamingantisch maar ook links. Hij was de stichter van het Algemeen Vlaamsch Demokratisch Verbond, een soort soldatenvakbond, die slechts korte tijd bestond, maar toch even een gevaarlijke rivaal voor de Frontbeweging zou geweest zijn. Pira en zijn organisatie werden door de Militaire Veiligheid zeer snel uitgeschakeld. Na de oorlog werd hij tot twintig jaar gevangenisstraf veroordeeld, onder andere omdat hij zou aangezet hebben tot desertie.

Over de achtergrond van Pira was tot voor kort weinig bekend. De schaarse gegevens berustten vooral op subjectieve herinneringen en oppervlakkig onderzoek. Op basis van een aantal nooit eerder gebruikte bronnen en van een nieuwe studie van zijn militaire dossier en van de beschikbare gerechtelijke documenten, schetsen de auteurs het traject van Pira voor, tijdens en na zijn acties aan het front. Ze toetsen hun conclusies aan het beeld dat van Pira wordt opgehangen in een aantal publicaties en komen tot het besluit dat dit deels op gebrekkig onderzoek en wensdenken gevestigd is, wat geleid heeft tot de 'mythische' voorstelling van Antoon Pira als een uiterst linkse radikaal.

Flemish Soviets at the Yser?
The life and works of Antoon Pira (1887-1939): end of a myth

Following a short biographical note which was published in 1968, Antoon Pira became a household name in the historiography of the Front Movement. Often referred to as an inconsequential radical figure, the flamingant (but also leftist) Pira was the founder of the Algemeen Vlaamsch Demokratisch Verbond (General Flemish Democratic Union), a type of military labor union which, though short-lived, was briefly considered a potentially strong competitor by the Front Movement. The Belgian Military’s security apparatus however would rapidly dispose of Pira and his organization. Pira was afterwards sentenced to twenty years in jail on charges (among others) of enticing desertion.
Pira’s background remained largely unknown hitherto, since those few ‘facts’ that were brought to light were largely based upon subjective recollections and superficial research. Based on never-
used sources and a new analysis of Pira’s military file and judicial documents, the authors draw a picture of Pira’s trials and tribulations before, during and after his actions at the warfront. Confronting their findings with the common portrayal of Pira in a number of publications, the authors conclude that due to insufficient research and wishful thinking, a myth-inducing portrayal of Pira as an extreme-left radical was able to emerge.
Exposure of Pinus elliottii wood treated with titanium dioxide to the fungus Postia placenta and photodegradation
Authors: Zanatta Paula , Mattoso Taline , Gallio Ezequiel , Lazarotto Marília , Gatto Darci Alberto , Da Cunha Alexsandro Bayestorff , Beltrame Rafael
Published: July 2022

It was impregnated commercial titanium dioxide into Pinus elliottii wood, aiming to increase its durability against the attack of brown rot fungus Postia placenta and photodegradation caused by ultraviolet radiation. The samples were put under 8 bar pressure for 3 hours at different concentrations of TiO2 (0.5%, 0.25%, 0.124% and 0%-control). To evaluate the effect of the fungus on the wood, the test was carried out according to ASTM D2017-05 and UNE-EN 113:1996 with modifications. The photodegradation was performed by exposing a tangential section to ultraviolet radiation for 400 hours, and the colorimetric parameters were periodically evaluated. Statistically, the treatments with TiO2 did not differ among themselves, but were much lower than the control, showing the effectiveness of this product in protecting the wood against the attacks of degraders. As for the photodegradation, the treated wood remained practically unchanged, differently from the control that had a darkening accelerated mainly in the first 50 hours. With this information, it can be stated that TiO2 treated wood is able to hinder the fungus access to the cell wall, to inhibit its growth and to create a barrier that protects the polymers from photodegradation, increasing its durability and emerging as a potential alternative for wood treatment.
Diabetes Self-management Apps: Systematic Review of Adoption Determinants and Future Research Agenda (Preprint)
Authors: Alaslawi Hessah , Berrou Ilhem , Al Hamid Abdullah , Alhuwail Dari , Aslanpour Zoe
Published: July 2022

BACKGROUND

Most diabetes management involves self-management. Effective self-management of the condition improves diabetes control, reduces the risk of complications, and improves patient outcomes. Mobile apps for diabetes self-management (DSM) can enhance patients’ self-management activities. However, they are only effective if clinicians recommend them, and patients use them.

OBJECTIVE

This study aimed to explore the determinants of DSM apps’ use by patients and their recommendations by health care professionals (HCPs). It also outlines the future research agenda for using DSM apps in diabetes care.

METHODS

We systematically reviewed the factors affecting the adoption of DSM apps by both patients and HCPs. Searches were performed using PubMed, Scopus, CINAHL, Cochrane Central, ACM, and Xplore digital libraries for articles published from 2008 to 2020. The search terms were diabetes, mobile apps, and self-management. Relevant data were extracted from the included studies and analyzed using a thematic synthesis approach.

RESULTS

A total of 28 studies met the inclusion criteria. We identified a range of determinants related to patients’ and HCPs’ characteristics, experiences, and preferences. Young female patients were more likely to adopt DSM apps. Patients’ perceptions of the benefits of apps, ease of use, and recommendations by patients and other HCPs strongly affect their intention to use DSM apps. HCPs are less likely to recommend these apps if they do not perceive their benefits and may not recommend their use if they are unaware of their existence or credibility. Young and technology-savvy HCPs were more likely to recommend DSM apps.

CONCLUSIONS

Despite the potential of DSM apps to improve patients’ self-care activities and diabetes outcomes, HCPs and patients remain hesitant to use them. However, the COVID-19 pandemic may hasten the integration of technology into diabetes care. The use of DSM apps may become a part of the new normal.
The effect of long working hours on mental health among Chinese medical residents: A multi-center cross-sectional study (Preprint)
Authors: Bai Song , Li Zhiyuan , Liu Dongmei , Liu Xiuping , Su Hui
Published: July 2022

BACKGROUND

Long working hours are common among medical residents and may increase the risk of mental disorders.

OBJECTIVE

We aimed to investigate this risk among Chinese medical residents.

METHODS

This multi-center, cross-sectional study was conducted in February 2020; 1,343 residents from eight hospitals in Northeastern China were included in the final analysis. The data were collected from participants via self-reported questionnaires. Depression and anxiety were measured by the Patient Health Questionnaire (PHQ-9) and the General Anxiety Disorder (GAD-7) scale, respectively. Adjusted odds ratios and 95% confidence intervals were determined after adjusting for potential confounders by binary unconditional logistic regression.

RESULTS

The effective response rate was 87.61%. Among the 1,343 participants, 12.88% (173), 9.90% (133), and 9.68% (130) had experienced major depression, major anxiety, and suicidal ideation, respectively. We found that longer weekly worktime increased the risk of major depression, particularly in those who worked for more than 60 hours per week (≥ 61 hours vs. ≤ 40 hours, OR=1.87, P for trend = 0.003). However, this trend was not observed for either major anxiety or suicidal ideation (P for trend > 0.05 for both).

CONCLUSIONS

This study revealed that there was a considerable incidence of poor mental health among medical residents; furthermore, the longer weekly worktime was associated with a higher risk of major depression, especial for those who worked more than 60 hours per week, but this association was not observed in either major anxiety or suicidal ideation. This may help policymakers to develop targeted interventions.
Tracción quirúrgica de caninos en paciente pediátrico con síndrome de Asperger. Caso clínico
Authors: Márquez-Encalada Brenda Marlene , Palacios-Salgado Daniel , López-García Esteban
Published: July 2022

Introducción. Los dientes retenidos son aquellos que presentan un retraso en su erupción o que no podrán erupcionar por sí solos. Los caninos superiores permanentes tienen más frecuencia de retención ósea después de los terceros molares. Este tipo de problemas bucodentales se pueden presentar aunado a otras alteraciones de salud sistémicas, psicológicas o cognitivas, entre los que se encuentra el Síndrome de Asperger (SA). En este sentido, el SA es un trastorno generalizado del desarrollo psico-cognitivo que afecta el funcionamiento social y el espectro de actividades e intereses. Debido a sus características, el SA es poco conocido, por ello muchos profesionales de las áreas educativa, social y médica no están suficientemente informados al respecto, de ahí la importancia de que los estudiantes de odontología tengan el conocimiento para atención clínica de dichos pacientes. Caso clínico. Paciente masculino de 12 años de edad, atendido en el Servicio de Odontopediatría. Al interrogatorio, la madre refiere que el paciente fue diagnosticado con SA a los tres años, por el cual acude a terapias. Considerando las dificultades de socialización de los pacientes con SA, se inició con interrogatorio e interacción gradual con el paciente, para su cooperación para el tratamiento. A la exploración intrabucal se observó ausencia de dientes 13 y 23. Manteniendo una comunicación y explicación paso a paso con el paciente, se inició el tratamiento colocando una barra transpalatina, se localizó el diente y se liberó de su saco pericoronario, se realizó limpieza de la zona y se colocó el botón con resina. Una vez colocado el botón se suturó y se dejó cicatrizar por siete días para después colocar el elástico en la barra transpalatina. Conclusiones. Tener el conocimiento sobre los problemas de salud sistémica, psicológicas y cognitivos, son fundamentales, para brindar una atención odontológica personalizada y sin riesgos. En este sentido, la socialización e interacción previa con los pacientes con SA, para explicarles la alteración bucodental y el tratamiento que se realizará son fundamentales para el manejo personalizado exitoso de la tracción quirúrgica de caninos. Palabras clave: Tratamiento dental, síndrome de Asperger, cuidado dental
Filosofía para Médicos. Mario Bunge
Authors: Sánchez-Nieto José Miguel
Published: July 2022

Mario Augusto Bunge (1919-2020) fue un filósofo autodenominado realista, cientificista, sistemista, materialista y humanista. Fue un autor prolífico, entre sus trabajos más conocidos esta su tratado de filosofía en el que realiza una sistematización de la ontología, la epistemología y la ética. En la investigación científica, uno de sus libros más conocidos es “la ciencia, su método y su filosofía”, en el que sintetiza las bases del método científico. Además, ha escrito números libros para identificar las bases filosóficas de diversas áreas de conocimiento, entre las que se encuentran la física, sociología, lingüística, psicología, la técnica y la medicina, este último es el que se describirá a continuación.
IMPLEMENTASI MOODLE PENGELOLAAN PEMBELAJARAN KELAS X SMA NEGERI 12 SIJUNJUNG
Authors: Fanda Yulian
Published: July 2022

The process of learning in SMA Negeri 12 Sijunjung still use the conventional way through face-to-face between teacher and students. Learning methods such as these have limitations that may hamper the delivery of science that developed quickly due to the limitations of time and place. From this condition then the e-Learning System is expected to become an alternative solution to overcoming existing limitations on SMA Negeri 12 Sijunjung especially in Class X. The goal of the research is to make it easy for teachers and students in teaching and learning activities, facilitate the access of all forms in the process of teaching and learning activities and make it easier to accept the results or information from the teaching and learning activities. As for the benefits that can be gained from the analysis and design of web-based E-learning it is can make it easier for students to obtain material and lessons, allowing teachers to distribute subject matter, open communication between teachers and students or between students outside of lessons through discussion forums. Development of e-learning uses a Content Management System (CMS) Moodle, while analysis using Flow Information System, for designing system using Hyrarcy Plus Input-Process-Output (HIPO), Data Flow diagrams (DFD), and Entity Relationship Diagram (ERD).
PENGARUH MEDIA LECTORA TERHADAP HASIL BELAJAR PESERTA DIDIK PADA MATERI PERANGKAT LUNAK MPEMBUAT GRAFIS DI SMA NEGERI 1 RAO
Authors: Hidayat1 Taufiq
Published: July 2022

This research was conducted because of SMA 1 Rao was already have adequate facilities to support learning process like library and computer room. However, in fact, the facility had not been used maximally in the learning process, especially in learning process of Information Communication and Technology (ICT) lesson. Some teachers also still used speech method and conversional media. In line with the problems, this research aimed to find out the effect of Lectora media as a learning media towards the students’ learning achievement in graphics software material at SMA Negeri 1 Rao. This research used a quantitative approach, and the subject of this research was SMA Negeri 1 Rao, the experimental class was XII.IPA-3 and XII.IPA-4 as control class. In data collection techniques, the researcher used questionnaires and tests. Questionnaires were distributed in the experimental class which used lectora media, and control class with no questionnaire because they did not use lectora media.The result of research showed that the effect of lectora media towards the learning achievement was the magnitude of effect of 5.1%, while the percentage between experiment class and control class were increasement of percentage of 42.5%, thus it was proven that the effect of lectora media to students' learning achievement was better than who did not use the lactor media.
THE REFLECTION OF MYTHOLOGICAL ELEMENTS AND SYMBOLS IN TURKISH MYTHOLOGY IN THE WORKS OF MEHMET
Authors: ÖZTÜRK Sümeyye , YAYAN Gonca
Published: July 2022

Throughout history, art has been both a means of communication for human beings and has made the ordinary flow of human life more meaningful. While the works that people made due to their needs in the early days were enriched with symbols through various communication ways, they developed with the concepts of art and artwork. Artists have given life to many works of art by nourishing the human spirit with art. Many elements, symbols and various concepts in the works of the artists gave various messages to the audience and thus contributed to their communication with them. Many artists used myths for the messages they tried to convey in their works and conveyed these messages to their audiences. Myths that mirror the past of societies; It is derived from the Greek words “Mythos” meaning story and “Logos” meaning word. Myths are stories that include the life adventures of gods, heroes, fairies and giants believed by many different nations in the past. In this way, information about the origin of human life, gods, natural events and legendary subjects can be reached through myths and symbols. Because myths are products of common cultural heritage in every society. It is known that the relations between cultures can be revealed through myths. These mythological elements play a major role in shaping cultures. In the research, there are evaluations such as how the mythological elements and symbols in Turkish mythology gain meaning in Mehmet Uygun's works and what impressions the symbols can leave on the audience. The works of Mehmet Uygun have been tried to be interpreted by analyzing them with their mythological meanings. Necessary permission was obtained from Mehmet Uygun regarding the article, and this research was carried out using descriptive method and scanning model.
P. CLODEMİR TROMPET METODUNUN İNCELENMESİ
Authors: ÜSTÜN Hamza
Published: July 2022

Müzik eğitiminin önemli bir alt öğrenme alanı olan çalgı eğitimi, başlangıç seviyesinden ustalık seviyesine çok geniş öğrenme öğretme yöntemlerinin kullanıldığı bir süreçtir. Her ne seviyede olunursa olunsun bu süreç içerisinde en önemli faktörlerden biri çalgının öğretiminde kullanılan metotlardır. Trompet eğitimi ülkemizde ve dünyada çok uzun bir süredir sistematik bir şekilde gerçekleşse de, trompet ile ilgili yazılan metotların sayısı oldukça azdır. Bu durum elde var olan metotların detaylı bir şekilde incelenerek en doğru metodun seçilmesinde kaynak oluşturması bakımından önemli bir husus olarak karşımıza çıkmaktadır. Bu araştırmada trompet eğitiminde sıklıkla kullanılan "P. Clodomir Methode Complete de Trompette a Pistons" metodu, başlangıç seviyesi, egzersizlerin içerikleri, ton durumları, gamlar ile ilgili bilgilendirmeler, çalış biçimleri ve düet içerikleri açılarından incelenmiştir. Araştırmada nicel araştırma yöntemlerinden içerik analizi kullanılmıştır. Araştırma sonucunda Clodemir metodunda yer alan toplam 252 egzersiz ve düet belirlenen özelliklere göre incelenmiştir. Bu bağlamlardan hareket ile, metodun başlangıç seviyesi açısından uygun olduğu, etütlerin sarmal bir şekilde ilerleyerek icracının gelişimini planladığı, dudak pozisyonu ve ağızlık kullanımı ile ilgili bilgilere yer verilmediği, öğretmen öğrenci düetlerinde seviyenin göz ardı edildiği sonuçlarına ulaşılmıştır. İncelenen egzersizlerin %16,7'si başlangıç seviyesi, %51,9'u orta seviye ve %31,4'ünün ise ileri seviye çalıcı becerileri gerektirdiği belirlenmiştir. Elde edinilen sonuçlar ilgili bölümlerde tablolaştırılarak açıklanmıştır. Araştırmanın trompet eğitimcilerine ve öğrencilerine yol gösterici bir kaynak olacağı düşünülmektedir.
CAMİ CEMAATİNİN CAMİ MÜZİĞİNE YÖNELİK GÖRÜŞLERİ
Authors: BOZDEMİR Büşra Sena , GÖKTAŞ Uğur
Published: July 2022

Yüzyıllardır nesilden nesle aktarılan ve İslam dünyasında ezan, kamet, sala, tesbihat, temcid, münacat, tekbir vb. formlarıyla yoğun bir şekilde icra edilen Cami müziği, cemaat tarafından işitilmektedir. Cami müziğinin müzik ilmini bilen, sesi güzel olan cami imamları ve müezzinler tarafından icra edilmesinin cemaat üzerinde olumlu etki bıraktığı gözlemlenirken bunun aksi durumlarda cemaatin hoşnutsuzluğu dikkat çekmektedir. İslam ve müzik arasında helal-haram konularının tartışılır olması, cemaatte de kafa karışıklıklarına yol açmaktadır. Araştırmamız bu noktadan yola çıkarak, imam ve müezzinlerin cami müziğini kullanma biçimlerine göre cemaat üzerinde bıraktığı etkiler incelenmek istenmiştir. Araştırma neticesinde elde edilecek verilerin cami müziğine yönelik cemaatin güncel bakış açısına olumlu yönde etki edebileceği düşünülmektedir. Araştırma durum tespiti yapmaya yönelik olup betimsel bir yapıya sahiptir. Araştırma sürecinde dijital ve yazılı kaynaklar taranarak konuya yönelik bilgiler elde edilmeye çalışılmış daha sonra cami müziğine yönelik cami cemaatlerinin görüşleri elde edilmeye çalışılmıştır. Araştırma sonuçlarının bazıları sıralanacak olursa, cami imamları, cami müezzinleri ve cami cemaatlerinin müziğin helal ya da haram olduğu konusunda kafa karışıklığı yaşadığı, imam ve müezzin yetiştiren resmi eğitim kurumlarında yeterli düzeyde müzik eğitimi verilmediğinin düşünüldüğü, imam ve müezzin yetiştiren resmi eğitim kurumlarında cami müziğini iyi derecede icra edebilen mezunların verilmediğinin düşünüldüğü, imam ve müezzinlerin iyi derecede cami müziğini icra etmesi gerektiğinin düşünüldüğü, cami müziğinin etkili bir şekilde icra edilmesinden cemaatin olumlu etkilendiği, imam ve müezzinlerin ses güzelliği ve icra kabiliyetlerine göre cemaatin olumlu ya da olumsuz duygular geliştirdiği ilk akla gelen sonuçlarımızdan bazılarıdır.
TÜRK HALK MÜZİĞİ BAĞLAMINDA DEĞERLER EĞİTİMİ BOYUTUYLA BAĞLAMANIN SOSYO-KÜLTÜREL, EKONOMİK VE DİNSEL BİR ÇALGI OLARAK KULLANIMI
Authors: DURSUN Doğukan , KARAGÖZ DURSUN Betül
Published: July 2022

Bu çalışmada; Türk Halk Müziği bağlamında değerler eğitimi boyutuyla bağlamanın sosyo-kültürel, ekonomik ve dinsel bir çalgı olarak kullanımından bahsedilmiştir. Değerler eğitimi temelinde Halk müziği, Türk Halk Müziğinin oluşumu, Türk Halk Müziğinin en önemli çalgısı ve aynı zamanda Türk Halk kültürünün en önemli değerlerinden biri olan bağlamanın türü ve günümüze kadar ulaşan süreçte adıyla birlikte uğradığı değişimlerden bahsedilmiştir. Geçen zamanda yapısal olarak değişime uğrayan bağlamanın, günümüzde kullanılan boyutları, teknik yapısı ve kullanım alanlarıyla ilgili bilgiler ile sosyo-kültürel, ekonomik ve dini bir değer olarak önemi derinlemesine irdelenmiştir. Türk Halk Müziği temelinde bağlama çalgısının; sosyo-kültürel, ekonomik ve dinsel bir değer olarak kullanımına, zaman içindeki farklılıklarına ve değişimlerine, türlerine, oluşumuna, Türk kültüründeki yerine ve önemine değinilmiştir. Ayrıca bağlamanın yörelerimizdeki sesli kültür taşıyıcısı olarak öneminden ve bu noktada Âşıklık geleneğine olan katkısından bahsedilmiştir. Âşıklar, söyledikleri sözlerle halkın duygularına tercüman olmuş ve halkın ifade edemediği duygu ve düşüncelerini sazlarıyla etkili bir şekilde dile getirmişlerdir. Bu anlamda bağlamanın ne kadar önemli bir değer olduğu ve benimsendiği sonucuna ulaşılmıştır. Ayrıca bağlamanın ekonomik boyutuna değinilerek, günümüzdeki teknolojik gelişmelerle birlikte son şeklini alan elektronik bağlamanın kullanım alanları hakkında bilgi verilmiştir. Bu çalışmada, başlangıcından günümüze bağlama çalgısının türleri sınıflandırılarak sunulmuş ve yorumlanmıştır. Araştırma sonucunda, bağlama çalgısının Türk kültüründe önemli bir yere sahip olduğu, Türk Halk Müziği icrasındaki en önemli saz olduğu, kültürel değerlerin aktarımında değerler eğitimi açısından da önemli bir çalgı olduğu ve sadece kültürel bir öğe olmayıp, dini törenlerde de kullanılan, kutsallığı olan bir değer olarak yer aldığı sonuçlarına ulaşılmıştır.
Implementation of Experiential Learning Theory in Islamic Religious Education during Covid-19 Pandemic
Authors: Apriliana Evita Nur , Tamami Ulya Barokati , Sutiyono Agus
Published: July 2022

The purpose of this study is to demonstrate how experiential learning theory was applied in Islamic religious education during the covid-19 epidemic. Interviews and observations are used to acquire primary data, whereas documentation studies obtain secondary data. This research was conducted at SMP Takhassus Al-Qur'an Tarub Tegal and SMA N 1 Karanggede, Boyolali. The data validity test is accomplished by triangulating the data analysis sources utilizing Miles and Huberman analysis, which consists of three stages: data reduction, data visualization, and data verification. The findings indicated that experiential learning theory might be applied to pandemic education in four stages: tangible experience, reflective observation, abstract conceptualization, and active experimentation, both offline and online learning. Experience-based Islamic religious education helps students learn, comprehend, live, and practice Islamic teachings.
Paradigma Islam Wasatiyah Ulama Aceh: Studi Pemikiran Tu Sop Jeunib
Authors: Zulkhairi Teuku
Published: July 2022

Artikel ini menggambarkan paradigma pemikiran Islam Wasaṭiyah salah seorang ulama Aceh, Tgk. H. Muhammad Yusuf A. Wahab atau lebih dikenal dengan panggilan Tu Sop Jeunieb yang saat ini menjabat sebagai Ketua Himpunan Ulama Dayah Aceh (HUDA). Tu Sop aktif berdakwah dengan lisan dan perbuatan. Untuk memperluas jangkauan dakwahnya, Tu Sop juga memanfaatkan sarana-sarana dakwah modern seperti media sosial, radio, website dan lainnya. Cakupan dakwahnya meliputi aspek politik, sosial, moral spiritual, aqidah dan akhlak, motivasi dan pendidikan. Penelitian ini menggunakan pendekatan kualitatif dengan objek studi pemikiran tokoh. Data dikumpulkan melalui telaah dokumen, observasi dan wawancara mendalam. Data kemudian dianalisis secara interpretatif. Hasil penelitian menunjukkan bahwa pemikiran Tu Sop Jeunieb menekankan aspek-aspek pendekatan moderasi Islam atau pandangan “pertengahan” dalam beragama. Narasi Tu Sop senantiasa berada di tengah-tengah antara dua benturan dengan tujuan menemukan titik temu dalam perbedaan. Tu Sop memandang mazhab Ahlusunnah wal Jamā’ah secara Wasaṭiyah. Paradigma Islam Wasatiyah Tu Sop Jeunieb antara lain yaitu berorientasi kepada persatuan (Wiḥdat al-Ummah), berakhlak dan menjaga rasa aman, seimbang antara dunia dan akhirat, seimbang antara akal dan teks suci, orientasi kepada kebaikan, hikmah dan nasehat yang baik, menolak segala macam penyimpangan. Hasil penelitian ini sangat penting sebagai pedoman dalam membumikan konsep Islam Wasaṭiyah yang kian dibutuhkan akhir-akhir ini, khususnya saat umat Islam dihadapkan pada berbagai potensi konflik dan perpecahan.
Ekstrakurikuler di Pesantren Moderen: Sebuah Upaya dalam Pembentukan Karakter Santri
Authors: Emawati Emawati , Masyitah Istiqamahtul
Published: July 2022

Private Islamic Boarding Schools have received large audiences. Most people regardless of their economic and social status send their children to Islamic boarding schools. There are reasons parents choose this kind of school over other types of school, one of which is the fact that this type of schooling offers a wide variety of extra-curricular activities. This study seeks to identify the roles of extracurricular in shaping students’ character in a particular boarding school. This qualitative multi-site case study interviewed the management of the boarding schools, teachers, and students. The data for the research was also revealed through observation of students’ activities during the extra-curricular program. Our research suggests that extra-curricular were believed to have shaped students’ characters. The extra-curricular program shape students to become more disciplined, develop time-management skill, become more independent, and develop students’ creativities and students’ critical thinking. Our findings also reveal that the extra-curricular activities were run at a specified time, which does not distract students’ schedule for main learning activities.
ICTs use since an interdisciplinary approach for support the training on ophidism a public health problem
Authors: Guerrero Vargas Jimmy Alexander , Rengifo Rios Angie Marcela , Bueno Ospina Mary Luz , Ayerbe González Santiago , Cruz Ordóñez Luis Alejandro
Published: July 2022

The present research and development work focuses on ophidism or ophidic accidentthat is a forgotten public health problem, which is normally focused on antiophidic serumapplication. Complications are sometimes caused by the patients; delay to go to amedical centre and the health professionals lacking knowledge of the ophidismtreatment. In this work, we design under canvas model a Massive Open Online Course(MOOC) on introduction to ophidic accident giving a new accessible, massive anddynamic training strategy. It is nourished by the students’ contribution; unlike traditionaltraining programmes. For this reason, it is intended to promote other forms of training onprevention and knowledge of the ophidic accident, which are priority activities in theColombian territory. To end, we highlight that there exist a considerable number ofunderestimated cases due to the inadequate registration of the notification forms.
Percepción de estudiantes de ingeniería sobre la enseñanza remota mediante la estrategia de aula-invertida
Authors: Pertuz Said
Published: July 2022

Este documento reporta los resultados de un estudio de la percepción de los estudiantes sobre la enseñanza remota mediante el método de aula invertida en comparación con dos estrategias de enseñanza-aprendizaje presencial: cátedra clásica y aprendizaje basado en proyectos. El estudio de percepción sigue un diseño de cohorte donde los estudiantes tienen la oportunidad de experimentar las diferentes estrategias pedagógicas de forma secuencial y realizar una evaluación de percepción al final del curso. En la evaluación de percepción, se tienen en cuenta seis criterios: compren- sión y apropiación de conceptos teóricos, formación disciplinar, formación integral, dedicación y carga académica, interacción entre sujetos del proceso y aprendizaje activo. En un estudio piloto con 36 estudiantes de pregrado de ingeniería, la enseñanza remota mediante aula invertida es siempre mejor o igualmente valorada que las dos estrategias presen- ciales en todos los criterios considerados.
GRANULAR NETWORK TRAFFIC CLASSIFICATION FOR STREAMING TRAFFIC USING INCREMENTAL LEARNING AND CLASSIFIER CHAIN
Authors: Zaki Faiz , Afifi Firdaus , Gani Abdullah , Anuar Nor Badrul
Published: July 2022

In modern networks, network visibility is of utmost importance to network operators. Accordingly, granular network traffic classification quickly rises as an essential technology due to its ability to provide high network visibility. Granular network traffic classification categorizes traffic into detailed classes like application names and services. Application names represent parent applications, such as Facebook, while application services are the individual actions within the parent application, such as Facebook-comment. Most studies on granular classification focus on classification at the application name level. Besides that, evaluations in existing studies are also limited and utilize only static and immutable datasets, which are insufficient to reflect the continuous and evolving nature of real-world traffic. Therefore, this paper aims to introduce a granular classification technique, which is evaluated on streaming traffic. The proposed technique implements two Adaptive Random Forest classifiers linked together using a classifier chain to simultaneously produce classification at two granularity levels. Performance evaluation on a streaming testbed setup using Apache Kafka showed that the proposed technique achieved an average F1 score of 99% at the application name level and 88% at the application service level. Additionally, the performance benchmark on ISCX VPN non-VPN public dataset also maintained comparable results, besides recording classification time as low as 2.6 ms per packet. The results conclude that the proposed technique proves its advantage and feasibility for a granular classification in streaming traffic.
Hubungan Aktivitas Fisik dan Pengetahuan Gizi dengan Status Gizi Remaja Pasca Bencana di Kota Palu
Authors: Hartini Diah Ayu , Dewi Nikmah Utami , Aiman Ummu , Nurulfuadi Nurulfuadi , Ariani Ariani , Fitrasyah Siti Ika
Published: July 2022

Bencana gempa bumi, tsunami dan likuifaksi di Kota Palu berdampak pada masyarakat di segala aspek kehidupan, termasuk kondisi gizi pada remaja. Masalah gizi sangat rentan terjadi pada masa ini. Remaja berada pada fase pertumbuhan yang pesat, sehingga membutuhkan zat gizi yang jumlahnya relatif lebih besar. Masalah gizi yang sering ditemukan pada remaja adalah gizi kurang yang kemudian diperkuat dengan kondisi pasca bencana di Kota Palu yang memungkinkan kurangnya ketersediaan pangan. Selain itu, aktivitas fisik dan pengetahuan gizi merupakan faktor yang mempengaruhi status gizi. Penelitian ini ingin melihat hubungan antara aktivitas fisik dan pengetahuan gizi dengan status gizi pada remaja pasca bencana di Kota Palu. Jenis penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional yang dilaksanakan di SMA Negeri 4 Palu dengan populasi seluruh siswa kelas X dan XI serta sampel sebanyak 180 siswa. Hasil yang diperoleh yaitu aktivitas fisik responden lebih besar pada kategori sedang (60,6%) dan pengetahuan gizi responden lebih tinggi pada kategori kurang (90%). Berdasarkan hasil dari uji statistik, diperoleh adanya hubungan bermakna antara aktivitas fisik dengan status gizi remaja serta tidak adanya hubungan bermakna antara pengetahuan gizi dan status gizi remaja. Asupan energi yang berlebih jika tidak diimbangi dengan pengeluaran energi melalui aktivitas fisik maka akan berpengaruh pada penambahan berat badan yang juga mempengaruhi status gizi. Pengetahuan merupakan faktor tidak langsung yang mempengaruhi status gizi, sehingga perlu menilai berbagai faktor lain yang mungkin berhubungan dengan status gizi remaja di wilayah pasca bencana untuk merancang intervensi yang tepat memperbaiki status gizi pada remaja.
Karakteristik Organoleptik Dan Kandungan Gizi Bakso Ikan Kembung Dengan Substitusi Tepung Daun Kelor
Authors: Indraswari Sekar , Kurniasari Ratih , Fikri Al Mukhlas
Published: July 2022

Konsumsi ikan di Indonesia masih terbilang rendah dibandingkan dengan negara kepulauan lainnya. Salah satu olahan ikan yang dapat dimodifikasi dan dijangkau oleh masyarakat adalah bakso. Penggunaan ikan kembung dan tepung daun kelor dapat meningkatkan nilai kandungan gizi dalam bakso. Tujuan penelitian untuk menganalisis substitusi tepung daun kelor pada bakso ikan kembung terhadap karakteristik organoleptik dan kandungan gizi. Desain penelitian menggunakan Rancangan Acak Lengkap (RAL) dengan tiga perlakuan yang berbeda. Dengan proporsi ikan kembung dan tepung daun kelor perlakuan 711 (95:5), perlakuan 824 (90:10), dan perlakuan 930 (85:15). Analsis uji organoleptik menggunakan uji Kruskal Wallis dan uji lanjutan Mann-Whitney. Hasil analisis menunjukkan bahwa terdapat perbedaan yang nyata pada uji mutu hedonik dan uji hedonik (p<0.05). Perlakuan terbaik yaitu perlakuan 711 dengan proporsi ikan kembung 95 g dan tepung daun kelor 5 g. Substitusi tepung daun kelor secara nyata mempengaruhi karakteristik organoleptik bakso ikan kembung di setiap kategori (p<0.05). Kandungan gizi per 100 g bakso terbaik memiliki kadar air 62,77%, kadar abu 1,56%, kadar protein 11,71%, kadar lemak 0,97%, kadar zat besi 0,0155% (15,5 mg) dan kadar kalsium 0,4809% (480,9 mg). Dapat disimpulkan, proporsi bakso ikan kembung 95 g dan tepung daun kelor 5 g lebih baik dibandingkan dengan proporsi lainnya.