bluuebunny/crossref_metadata_2025 huggingface dataset:
Stable Bicyclic Functionalized Nitroxides: The Synthesis of Derivatives of Aza-nortropinone–5-Methyl-3-oxo-6,8-diazabicyclo[3.2.1]-6-octene 8-oxyls
Authors: Grigor’eva Larisa N. , Tikhonov Alexsei Ya. , Lomanovich Konstantin A. , Mazhukin Dmitrii G.
Published: May 2021

In recent decades, bicyclic nitroxyl radicals have caught chemists’ attention as selective catalysts for the oxidation of alcohols and amines and as additives and mediators in directed C-H oxidative transformations. In this regard, the design and development of synthetic approaches to new functional bicyclic nitroxides is a relevant and important issue. It has been reported that imidazo[1,2-b]isoxazoles formed during the condensation of acetylacetone with 2-hydroxyaminooximes having a secondary hydroxyamino group are recyclized under mild basic catalyzed conditions to 8-hydroxy-5-methyl-3-oxo-6,8-diazabicyclo[3.2.1]-6-octenes. The latter, containing a sterically hindered cyclic N-hydroxy group, upon oxidation with lead dioxide in acetone, virtually quantitatively form stable nitroxyl bicyclic radicals of a new class, which are derivatives of both 2,2,6,6-tetramethyl-4-oxopiperidine-1-oxyl (TEMPON) and 3-imidazolines.
Lead Levels in Non-Occupationally Exposed Women with Preeclampsia
Authors: Gajewska Katarzyna , Laskowska Marzena , Almeida Agostinho , Pinto Edgar , Skórzyńska-Dziduszko Katarzyna , Błażewicz Anna
Published: May 2021

There are many controversies regarding the relationship between lead exposure andcomplications in pregnancy. Preeclampsia (PE) is a maternal hypertensive disorder which is one of the main causes of maternal and foetal mortality. The aim of our study was to assess blood lead level (BLL) in Polish women with PE (PE group, n = 66) compared with healthy, non-pregnant women (CNP group, n = 40) and healthy pregnant women (CP group, n = 40). BLL was determined by inductively coupled plasma mass spectrometry (ICP-MS). The systolic blood pressure (SBP), diastolic blood pressure (DBP) and BLL in the CP group were significantly lower than in the PE group (p < 0.001). Logistic regression analyses of BLL showed a significant positive relationship with the presence of PE. Furthermore, both the SBP and DBP values were positively associated with BLL. This study indicates that preeclamptic women tend to present with significantly higher BLL compared to healthy pregnant women. There were no differences in the BLL between the CP and CNP groups.
Synthetic Iowaite Can Effectively Remove Inorganic Arsenic from Marine Extract
Authors: Ji Jing , Huang Wenwen , Wang Lingchong , Chen Lu , Wei Yuanqing , Liu Rui , Cheng Jianming , Wu Hao
Published: May 2021

For the removal of arsenic from marine products, iowaite was prepared and investigated to determine the optimal adsorption process of arsenic. Different chemical forms of arsenic (As(III), As(V)) with varying concentrations (0.15, 1.5, 5, 10, 15, and 20 mg/L) under various conditions including pH (3, 5, 7, 9, 11) and contact time (1, 2, 5, 10, 15, 30, 60, 120, 180 min) were exposed to iowaite. Adsorption isotherms and metal ions kinetic modeling onto the adsorbent were determined based on Langmuir, Freundlich, first- and second-order kinetic models. The adsorption onto iowaite varied depending on the conditions. The adsorption rates of standard solution, As(III) and As(V) exceeded 95% under proper conditions, while high complexity was noted with marine samples. As(III) and As(V) from Mactra veneriformis extraction all decreased when exposed to iowaite. The inclusion morphology and interconversion of organic arsenic limit adsorption. Iowaite can be efficiently used for inorganic arsenic removal from wastewater and different marine food products, which maybe other adsorbent or further performance of iowaite needs to be investigated for organic arsenic.
Evaluation of Aphicidal Effect of Essential Oils and Their Synergistic Effect against Myzus persicae (Sulzer) (Hemiptera: Aphididae)
Authors: Ahmed Qasim , Agarwal Manjree , Al-Obaidi Ruaa , Wang Penghao , Ren Yonglin
Published: May 2021

The insecticidal activities of essential oils obtained from black pepper, eucalyptus, rosemary, and tea tree and their binary combinations were investigated against the green peach aphid, Myzus persicae (Aphididae: Hemiptera), under laboratory and glasshouse conditions. All the tested essential oils significantly reduced and controlled the green peach aphid population and caused higher mortality. In this study, black pepper and tea tree pure essential oils were found to be an effective insecticide, with 80% mortality when used through contact application. However, for combinations of essential oils from black pepper + tea tree (BT) and rosemary + tea tree (RT) tested as contact treatment, the mortality was 98.33%. The essential oil combinations exhibited synergistic and additive interactions for insecticidal activities. The combination of black pepper + tea tree, eucalyptus + tea tree (ET), and tea tree + rosemary showed enhanced activity, with synergy rates of 3.24, 2.65, and 2.74, respectively. Essential oils formulation was effective on the mortality of aphids. Fourier Transform Infrared Spectroscopy (FTIR) analysis showed that stability of a mixture of essential oils was not affected by store temperature (15, 25, and 35 °C) and the functional groups were not changed during storage. Based on our results, the essential oils can be used as a commercial insecticide against M. persicae.
Functionalized Hydroperoxide Formation from the Reaction of Methacrolein-Oxide, an Isoprene-Derived Criegee Intermediate, with Formic Acid: Experiment and Theory
Authors: Vansco Michael F. , Zuraski Kristen , Winiberg Frank A. F. , Au Kendrew , Trongsiriwat Nisalak , Walsh Patrick J. , Osborn David L. , Percival Carl J. , Klippenstein Stephen J. , Taatjes Craig A. , Lester Marsha I. , Caravan Rebecca L.
Published: May 2021

Methacrolein oxide (MACR-oxide) is a four-carbon, resonance-stabilized Criegee intermediate produced from isoprene ozonolysis, yet its reactivity is not well understood. This study identifies the functionalized hydroperoxide species, 1-hydroperoxy-2-methylallyl formate (HPMAF), generated from the reaction of MACR-oxide with formic acid using multiplexed photoionization mass spectrometry (MPIMS, 298 K = 25 °C, 10 torr = 13.3 hPa). Electronic structure calculations indicate the reaction proceeds via an energetically favorable 1,4-addition mechanism. The formation of HPMAF is observed by the rapid appearance of a fragment ion at m/z 99, consistent with the proposed mechanism and characteristic loss of HO2 upon photoionization of functional hydroperoxides. The identification of HPMAF is confirmed by comparison of the appearance energy of the fragment ion with theoretical predictions of its photoionization threshold. The results are compared to analogous studies on the reaction of formic acid with methyl vinyl ketone oxide (MVK-oxide), the other four-carbon Criegee intermediate in isoprene ozonolysis.
Directional Plasmonic Excitation by Helical Nanotips
Authors: Singh Leeju , Maccaferri Nicolò , Garoli Denis , Gorodetski Yuri
Published: May 2021

The phenomenon of coupling between light and surface plasmon polaritons requires specific momentum matching conditions. In the case of a single scattering object on a metallic surface, such as a nanoparticle or a nanohole, the coupling between a broadband effect, i.e., scattering, and a discrete one, such as surface plasmon excitation, leads to Fano-like resonance lineshapes. The necessary phase matching requirements can be used to engineer the light–plasmon coupling and to achieve a directional plasmonic excitation. Here, we investigate this effect by using a chiral nanotip to excite surface plasmons with a strong spin-dependent azimuthal variation. This effect can be described by a Fano-like interference with a complex coupling factor that can be modified thanks to a symmetry breaking of the nanostructure.
SERRS Detection on Silver Nanoparticles Supported on Acid-Treated Melamine-Resin Microspheres
Authors: Duan Chaofeng , Shen Lu , Guo Yuqing , Wang Xiaogang , Wang Xiaohua , Hao Zhixian
Published: May 2021

Melamine-resin microspheres were synthesized at a pH of 4.0 for 20 min and used as silver nanoparticle (AgNP) carriers for surface enhanced resonant Raman scattering (SERRS) detection. An acetic acid–treatment reaction was introduced into the fabrication of the final substrate. The SERRS performance of the substrate was effectively optimized by regulating excess formaldehyde and experimental parameters, such as acidity, number of treatments and reaction temperature in the acid-treatment reaction. Based on the SERRS detection, it was declared that a trace amount of oligomers with a certain degree of polymerization is necessary for the construction of SERRS hotspots. In addition, it is important to remove excess oligomers with reference to the synthetic reaction of the polymer materials, given the special role of oligomers and the wide application of polymer materials in SERRS detection.
Molecular Dynamics Simulation for the Effect of Fluorinated Graphene Oxide Layer Spacing on the Thermal and Mechanical Properties of Fluorinated Epoxy Resin
Authors: Duan Qijun , Xie Jun , Xia Guowei , Xiao Chaoxuan , Yang Xinyu , Xie Qing , Huang Zhengyong
Published: May 2021

Traditional epoxy resin (EP) materials have difficulty to meet the performance requirements in the increasingly complex operating environment of the electrical and electronic industry. Therefore, it is necessary to study the design and development of new epoxy composites. At present, fluorinated epoxy resin (F-EP) is widely used, but its thermal and mechanical properties cannot meet the demand. In this paper, fluorinated epoxy resin was modified by ordered filling of fluorinated graphene oxide (FGO). The effect of FGO interlayer spacing on the thermal and mechanical properties of the composite was studied by molecular dynamics (MD) simulation. It is found that FGO with ordered filling can significantly improve the thermal and mechanical properties of F-EP, and the modification effect is better than that of FGO with disordered filling. When the interlayer spacing of FGO is about 9 Å, the elastic modulus, glass transition temperature, thermal expansion coefficient, and thermal conductivity of FGO are improved with best effect. Furthermore, we calculated the micro parameters of different systems, and analyzed the influencing mechanism of ordered filling and FGO layer spacing on the properties of F-EP. It is considered that FGO can bind the F-EP molecules on both sides of the nanosheets, reducing the movement ability of the molecular segments of the materials, so as to achieve the enhancement effect. The results can provide new ideas for the development of high-performance epoxy nanocomposites.
Electromagnetically Induced Transparency-Like Effect by Dark-Dark Mode Coupling
Authors: Wang Qiao , Kuang Kaili , Gao Huixuan , Chu Shuwen , Yu Li , Peng Wei
Published: May 2021

Electromagnetically induced transparency-like (EIT-like) effect is a promising research area for applications of slow light, sensing and metamaterials. The EIT-like effect is generally formed by the destructive interference of bright-dark mode coupling and bright-bright mode coupling. There are seldom reports about EIT-like effect realized by the coupling of two dark modes. In this paper, we numerically and theoretically demonstrated that the EIT-like effect is achieved through dark-dark mode coupling of two waveguide resonances in a compound nanosystem with metal grating and multilayer structure. If we introduce |1⟩, |2⟩ and |3⟩ to represent the surface plasmon polaritons (SPPs) resonance, waveguide resonance in layer 2, and waveguide resonance in layer 4, the destructive interference occurs between two pathways of |0⟩→|1⟩→|2⟩ and |0⟩→|1⟩→|2⟩→|3⟩→|2⟩, where |0⟩ is the ground state without excitation. Our work will stimulate more studies on EIT-like effect with dark-dark mode coupling in other systems.
Photosensing and Characterizing of the Pristine and In-, Sn-Doped Bi2Se3 Nanoplatelets Fabricated by Thermal V–S Process
Authors: Wang Chih-Chiang , Shieu Fuh-Sheng , Shih Han C.
Published: May 2021

Pristine, and In-, Sn-, and (In, Sn)-doped Bi2Se3 nanoplatelets synthesized on Al2O3(100) substrate by a vapor–solid mechanism in thermal CVD process via at 600 °C under 2 × 10−2 Torr. XRD and HRTEM reveal that In or Sn dopants had no effect on the crystal structure of the synthesized rhombohedral-Bi2Se3. FPA–FTIR reveals that the optical bandgap of doped Bi2Se3 was 26.3%, 34.1%, and 43.7% lower than pristine Bi2Se3. XRD, FESEM–EDS, Raman spectroscopy, and XPS confirm defects (In3+Bi3+), (In3+V0), (Sn4+Bi3+), (V0Bi3+), and (Sn2+Bi3+). Photocurrent that was generated in (In,Sn)-doped Bi2Se3 under UV(8 W) and red (5 W) light revealed stable photocurrents of 5.20 × 10−10 and 0.35 × 10−10 A and high Iphoto/Idark ratios of 30.7 and 52.2. The rise and fall times of the photocurrent under UV light were 4.1 × 10−2 and 6.6 × 10−2 s. Under UV light, (In,Sn)-dopedBi2Se3 had 15.3% longer photocurrent decay time and 22.6% shorter rise time than pristine Bi2Se3, indicating that (In,Sn)-doped Bi2Se3 exhibited good surface conduction and greater photosensitivity. These results suggest that In, Sn, or both dopants enhance photodetection of pristine Bi2Se3 under UV and red light. The findings also suggest that type of defect is a more important factor than optical bandgap in determining photo-detection sensitivity. (In,Sn)-doped Bi2Se3 has greater potential than undoped Bi2Se3 for use in UV and red-light photodetectors.
Recent Progress on the Characterization of Cellulose Nanomaterials by Nanoscale Infrared Spectroscopy
Authors: Zhu Qianqian , Zhou Rui , Liu Jun , Sun Jianzhong , Wang Qianqian
Published: May 2021

Researches of cellulose nanomaterials have seen nearly exponential growth over the past several decades for versatile applications. The characterization of nanostructural arrangement and local chemical distribution is critical to understand their role when developing cellulose materials. However, with the development of current characterization methods, the simultaneous morphological and chemical characterization of cellulose materials at nanoscale resolution is still challenging. Two fundamentally different nanoscale infrared spectroscopic techniques, namely atomic force microscope based infrared spectroscopy (AFM-IR) and infrared scattering scanning near field optical microscopy (IR s-SNOM), have been established by the integration of AFM with IR spectroscopy to realize nanoscale spatially resolved imaging for both morphological and chemical information. This review aims to summarize and highlight the recent developments in the applications of current state-of-the-art nanoscale IR spectroscopy and imaging to cellulose materials. It briefly outlines the basic principles of AFM-IR and IR s-SNOM, as well as their advantages and limitations to characterize cellulose materials. The uses of AFM-IR and IR s-SNOM for the understanding and development of cellulose materials, including cellulose nanomaterials, cellulose nanocomposites, and plant cell walls, are extensively summarized and discussed. The prospects of future developments in cellulose materials characterization are provided in the final part.
Growth Inhibitory Effects of Ester Derivatives of Menahydroquinone-4, the Reduced Form of Vitamin K2(20), on All-Trans Retinoic Acid-Resistant HL60 Cell Line
Authors: Yamakawa Hirofumi , Setoguchi Shuichi , Goto Shotaro , Watase Daisuke , Terada Kazuki , Nagata-Akaho Nami , Toki Erina , Koga Mitsuhisa , Matsunaga Kazuhisa , Karube Yoshiharu , Takata Jiro
Published: May 2021

The first-choice drug for acute promyelocytic leukemia (APL), all-trans retinoic acid (ATRA), frequently causes drug-resistance and some adverse effects. Thus, an effective and safe agent for ATRA-resistant APL is needed. Menaquinone-4 (MK-4, vitamin K2(20)), used for osteoporosis treatment, does not have serious adverse effects. It has been reported that MK-4 has growth-inhibitory effects on HL60 cells by inducing apoptosis via the activation of Bcl-2 antagonist killer 1 (BAK). However, the effect of MK-4 on ATRA-resistant APL has not been reported. Here, we show that ester derivatives of menahydroquinone-4 (MKH; a reduced form of MK-4), MKH 1,4-bis-N,N-dimethylglycinate (MKH-DMG) and MKH 1,4-bis-hemi-succinate (MKH-SUC), exerted strong growth-inhibitory effects even on ATRA-resistant HL60 (HL-60R) cells compared with ATRA and MK-4. MKH delivery after MKH-SUC treatment was higher than that after MK-4 treatment, and the results indicated apoptosis induced by BAK activation. In contrast, for MKH-DMG, reconversion to MKH was slow and apoptosis was not observed. We suggest that the ester forms, including monoesters of MKH-DMG, exhibit another mechanism independent of apoptosis. In conclusion, the MKH derivatives (MKH-SUC and MKH-DMG) inhibited not only HL60 cells but also HL-60R cells, indicating a potential to overcome ATRA resistance.
Disposal Practices of Unused and Leftover Medicines in the Households of Dhaka Metropolis
Authors: Begum Mst. Marium , Rivu Sanzana Fareen , Hasan Md. Mahmud Al , Nova Tasnova Tasnim , Rahman Md. Motiar , Alim Md. Abdul , Uddin Md. Sahab , Islam Azharul , Nurnahar Nurnahar , Tabassum Nuzhat , Moni Md. Marufur Rahman , Roselin Rehnuma , Das Munny , Begum Rayhana , Rahman Md. Sohanur
Published: May 2021

Background: This fact-finding study aimed to attain an overall idea and knowledge about medicine disposal practices in Dhaka Metropolitan households. Methods: This mixed study (both quantitative and qualitative) was orchestrated to inspect the household leftover medicine disposal pattern’s governing status. A cross-sectional survey was conducted following a structured questionnaire and key informant interview with a household person and in-depth interviews with the top pharmaceutical and government officials. Results: Findings disclose that, for most of the key informants, the terms “drug disposal” and “drug pollution” were unknown; more precisely, 67% and 74% of key informants even did not hear these two terms. Almost all (87%) households faced undesired incidents due to the insecure storage of medicines. People disposed of excess and expired medication in regular dustbins (47%), threw out of the window (19%), flushed within commode (4%), burnt in fire (2%), and reused (4%). A good percentage of people (21%) returned unexpired drugs to the pharmacy and bought other medicines on a need basis. A total of 72% wanted a medicine take-back program, and 100% agreed on mass education on this issue. Officials of pharmaceuticals conferred mixed opinion: top-ranked pharmaceuticals will adopt leftover medicine disposal practices; middle and low-ranked pharmaceutical companies are reluctant, merely denied mentioning the less important issue. Conclusions: The absence of mass awareness and standard laws and policies may explain these existing aberrant practices.
On Russell’s 1927 Book The Analysis of Matter
Authors: Mikki Said
Published: May 2021

The goal of this article is to bring into wider attention the often neglected important work by Bertrand Russell on the philosophy of nature and the foundations of physics, published in the year 1927. It is suggested that the idea of what could be named Russell space, introduced in Part III of that book, may be viewed as more fundamental than many other types of spaces since the highly abstract nature of the topological ordinal space proposed by Russell there would incorporate into its very fabric the emergent nature of spacetime by deploying event assemblages, but not spacetime or particles, as the fundamental building blocks of the world. We also point out the curious historical fact that the book The Analysis of Matter can be chronologically considered the earliest book-length generic attempt to reflect on the relation between quantum mechanics, just emerging by that time, and general relativity.
Extended L-Band InAs/InP Quantum-Dash Laser in Millimeter-Wave Applications
Authors: Ragheb Amr M. , Tareq Qazi , Alkhazraji Emad , Esmail Maged A. , Alshebeili Saleh , Khan Mohammed Zahed Mustafa
Published: May 2021

We report on the generation and transmission of a millimeter-wave (MMW) signal with a frequency of 28 GHz by employing an InAs/InP quantum-dash dual-wavelength laser diode (QD-DWL) emitting in the ~1610 nm extended L-band window. The self-injection locking (SIL) technique has been engaged to improve the linewidth and reduce the noise of the optical tone. Besides, the transmission of a 2 Gbits/s quadrature phase-shift keying (QPSK)-modulated 28-GHz MMW beat tone over a hybrid 20-km radio-over-fiber combined with 5-m radio-over-free-space-optics and up to 6-m radio frequency wireless link has been demonstrated. Moreover, comparing the proposed QD-DWL with a commercial laser showcased similar performance characteristics, making the QD-DWL a candidate source for MMW applications.
Deep Learning-Assisted Index Estimator for Generalized LED Index Modulation OFDM in Visible Light Communication
Authors: Le-Tran Manh , Kim Sunghwan
Published: May 2021

In this letter, we present the first attempt of active light-emitting diode (LED) indexes estimating for the generalized LED index modulation optical orthogonal frequency-division multiplexing (GLIM-OFDM) in visible light communication (VLC) system by using deep learning (DL). Instead of directly estimating the transmitted binary bit sequence with DL, the active LEDs at the transmitter are estimated to maintain acceptable complexity and improve the performance gain compared with those of previously proposed receivers. Particularly, a novel DL-based estimator termed index estimator-based deep neural network (IE-DNN) is proposed, which can employ three different DNN structures with fully connected layers (FCL) or convolution layers (CL) to recover the indexes of active LEDs in a GLIM-OFDM system. By using the received signal dataset generated in simulations, the IE-DNN is first trained offline to minimize the index error rate (IER); subsequently, the trained model is deployed for the active LED index estimation and signal demodulation of the GLIM-OFDM system. The simulation results show that the IE-DNN significantly improves the IER and bit error rate (BER) compared with those of conventional detectors with acceptable run time.
Optimized Omnidirectional High-Reflectance Using Octonacci Photonic Crystal for Thermographic Sensing Applications
Authors: Ali Naim Ben , Trabelsi Youssef , Alsaif Haitham , Bouazzi Yasssine , Kanzari Mounir
Published: May 2021

The transmittance of waves through one-dimensional periodic and Octonacci photonic structures was studied using the theoretical transfer matrix method for both wave-polarization-modes. The first structures were made up of the SiO2 and TiO2 materials. The objective here was to obtain a broad omnidirectional high reflector covering the infrared spectrum of a thermographic camera [1–14 µm] and, especially, to prevent the transmission of emitted human body peak radiation λmax = 9.341 µm. By comparing the periodic and Octonacci structures, we found that the last structure presented a main and wide photonic band gap near this human radiation. For that, we kept only the Octonacci structure for the rest of the study. The first structure did not give the aspired objective; thus, we replaced the TiO2 layers with yttrium barium copper oxide material, and a significant enhancement of the omnidirectional photonic band gap was found for both TE and TM polarization modes. It was shown that the width of this band was sensitive to the Octonacci iteration number and the optical thickness (by changing the reference wavelength), but it was not affected by the ambient temperature. The number of layers and the thickness of the structure was optimized while improving the omnidirectional high reflector properties.
Investigation on Speckle-Free Imaging at the Output of a Multimode Fiber under Various Mode Excitation Conditions
Authors: Zhou Jun , Le Zichun , Guo Yanyu , Liu Zongshen , Xu Qiyong , Dai Yanxin , Deng Jiayu , Li Jiapo , Cai Di
Published: May 2021

Speckle-free imaging using a multimode fiber has been widely used for imaging systems. Generally, previous work has assumed that all the propagating modes of the fiber are uniformly excited, but the modal power distribution is actually affected by excitation conditions. Here, we propose the utilization of a modal analysis method to study the dependence of the speckle contrast on the modal power distribution by changing the tilt angle of the Gaussian beam and on the group delay time difference caused by different fiber lengths. The results of numerical simulations and experiments show that, with an increase in the tilt angle of the Gaussian beam, the modal power is transferred to higher-order modes and the maximum delay difference between excitation modes becomes larger. Therefore, the inter-mode interference effect is effectively weakened, and the speckle contrast is significantly reduced. The increase in fiber length will also make the delay difference between excitation modes larger and thus the speckle contrast is decreased. For the larger tilt angle of the Gaussian beam, only a shorter optical fiber is required to reduce the speckle contrast significantly. Our work further promotes the use of a multimode fiber to produce speckle-free patterns in laser imaging systems.
Detection and Distribution of Viruses Infecting Garlic Crops in Australia
Authors: Cremer Julia , Campbell Paul , Steele Visnja , Persley Denis , Thomas John , Harper Stephen , Gambley Cherie
Published: May 2021

The distribution of viruses in eastern Australian field garlic was evaluated. Detection assays were developed that involved generic RT-PCR for viruses in the Allexivirus, Carlavirus and Potyvirus genera followed by virus-specific colorimetric dot-blot hybridization. Assays targeted the potyviruses (onion yellow dwarf virus (OYDV), shallot yellow stripe virus (SYSV), and leek yellow stripe virus (LYSV)), the carlaviruses (garlic common latent virus (GCLV) and shallot latent virus (SLV)), and the allexiviruses (garlic viruses A, B, C, X (GarVA, -B, -C, -X) and shallot virus X (ShVX)). Virus incidence in crops was consistently high, with most plants infected with at least one virus from each genus. OYDV, LYSV, SLV, and GCLV were commonly detected. Three of the four allexiviruses were in all districts surveyed but varied in incidence, whereas ShVX and SYSV were not detected. There was no association between virus species complement and bulb size, indicating size is not a good predictor of the virus status of planting material. The variation of virus incidence across different Australian growing districts and in different cultivars implies multiple introductions of viruses rather than spread within the country. The genetic diversity observed within coat protein sequences of some virus species also supports multiple separate introductions.
Influence of Climate Warming on Grapevine (Vitis vinifera L.) Phenology in Conditions of Central Europe (Slovakia)
Authors: Bernáth Slavko , Paulen Oleg , Šiška Bernard , Kusá Zuzana , Tóth František
Published: May 2021

The impact of warming on the phenology of grapevine (Vitis vinifera L.) in conditions of central Europe was evaluated at the locality of Dolné Plachtince in the Slovakian wine region. In Welschriesling and Pinot Blanc model varieties, the onset of phenophases as defined in the BBCH scale over the period of 1985 to 2018 was observed. Based on the data obtained, the influence of the average and average maximum temperature and GDD on the onset of phenophases was evaluated. The results observed indicate earlier budburst by five to seven days, earlier beginning of flowering by 7 to 10 days, earlier berry softening by 18 days, and harvest dates advanced by 8 to 10 days on average. In both varieties, the highest influence of the average monthly temperature in March on budburst, the highest influence of the average monthly temperature and the average maximum temperature in May on the beginning of flowering, and the highest statistically significant influence of the average maximum temperature in June on the softening of berries was found. Warming observed in moderate climate conditions of northern wine regions in central Europe (Slovakia) has not yet caused changes in the grapevine phenology stable enough to require serious adaptation measures.
Regions of Chromosome 2A of Bread Wheat (Triticum aestivum L.) Associated with Variation in Physiological and Agronomical Traits under Contrasting Water Regimes
Authors: Pshenichnikova Tatyana A. , Osipova Svetlana V. , Smirnova Olga G. , Leonova Irina N. , Permyakova Marina D. , Permyakov Alexey V. , Rudikovskaya Elena G. , Konstantinov Dmitrii K. , Verkhoturov Vasiliy V. , Lohwasser Ulrike , Börner Andreas
Published: May 2021

Understanding the genetic architecture of drought tolerance is of great importance for overcoming the negative impact of drought on wheat yield. Earlier, we discovered the critical role of chromosome 2A for the drought-tolerant status of wheat spring cultivar Saratovskaya 29. A set of 92 single-chromosome recombinant double haploid (SCRDH) lines were obtained in the genetic background of Saratovskaya 29. The lines carry fragments of chromosome 2A from the drought-sensitive cultivar Yanetzkis Probat. The SCRDH lines were used to identify regions on chromosome 2A associated with the manifestation of physiological and agronomical traits under distinct water supply, and to identify candidate genes that may be associated with adaptive gene networks in wheat. Genotyping was done with Illumina Infinium 15k wheat array using 590 SNP markers with 146 markers being polymorphic. In four identified regions of chromosome 2A, 53 out of 58 QTLs associated with physiological and agronomic traits under contrasting water supply were mapped. Thirty-nine candidate genes were identified, of which 18 were transcription factors. The region 73.8–78.1 cM included the largest number of QTLs and candidate genes. The variation in SNPs associated with agronomical and physiological traits revealed among the SCRDH lines may provide useful information for drought related marker-assisted breeding.
Differences in Leaf Morphological Parameters of Pear (Pyrus communis L.) Based on Their Susceptibility to European Pear Rust Caused by Gymnosporangium sabinae (Dicks.) Oerst.
Authors: Kārkliņa Katrīna , Lācis Gunārs , Lāce Baiba
Published: May 2021

European pear rust is an important disease; however, the relationship between its causal pathogen Gymnosporangium sabinae (Dicks.) Oerst. and host Pyrus communis L. is poorly understood. In this study, disease severity was measured, and leaf samples were collected over three years, and their leaf water content; leaf area; leaf mass per area; and epidermis, mesophyll, and vascular tissue width and stomatal density were measured and compared between susceptible and resistant genotypes for each year. Most genotypes either showed consistent disease symptoms or showed no symptoms during the study in terms of their susceptibility. A correlation between disease severity and mesophyll tissue thickness, and stomatal density and differences between several morphological parameters were found depending on the genotype’s susceptibility. The study showed that the following pear morphological traits were stable between the years: water content, leaf mass per area, spongy mesophyll thickness, phloem thickness, and stomatal density. When selecting for breeding, we found that candidates for traits that discern susceptible genotypes from resistant were mesophyll layer width, stomatal density, epidermis width, and xylem tissue width.
Bacillus thuringiensis and Silicon Modulate Antioxidant Metabolism and Improve the Physiological Traits to Confer Salt Tolerance in Lettuce
Authors: ALKahtani Muneera , Hafez Yaser , Attia Kotb , Al-Ateeq Talal , Ali Mohamed A. M. , Hasanuzzaman Mirza , Abdelaal Khaled
Published: May 2021

We investigated the impact of Bacillus thuringiensis as seed treatment and application with silicon on lettuce plants exposed to salinity levels (4 dS m−1 and 8 dS m−1). Results revealed that leaves number, head weight, total yield, relative water content (RWC), and chlorophyll a and b declined considerably due to two salinity levels. Oxidative stress markers, i.e., hydrogen peroxide (H2O2), superoxide (O2−), and lipid peroxidation (MDA) dramatically augmented in stressed plants. On the other hand, leaves number, total yield, RWC, and chlorophyll a, b in stressed lettuce plants were considerably enhanced because of the application of Si or B. thuringiensis. In contrast, EL%, MDA, and H2O2 were considerably reduced in treated lettuce plants with Si and B. thuringiensis. In addition, the treatment with Si and B. thuringiensis increased head weight (g) and total yield (ton hectare-1), and caused up-regulation of proline and catalase, superoxide dismutase, peroxidase, and polyphenol oxidase activity in lettuce leaves under salinity conditions.
Oenothein B, a Bioactive Ellagitannin, Activates the Extracellular Signal-Regulated Kinase 2 Signaling Pathway in the Mouse Brain
Authors: Okuyama Satoshi , Furukawa Yoshiko , Yoshimura Morio , Amakura Yoshiaki , Nakajima Mitsunari , Yoshida Takashi
Published: May 2021

(1) Background: Oenothein B, a cyclic dimeric ellagitannin present in various medicinal plants, has been reported to exert diverse effects that are beneficial for the treatment and prevention of diseases, including cancer and infections. We recently showed that oenothein B also functions in the brain because its oral administration to systemic inflammatory model mice reduced inflammatory responses in the brain and suppressed abnormal behavior. (2) Results: The present in vivo results demonstrated that oenothein B activated extracellular signal-regulated kinase 2 and cAMP response element-binding protein in the brain, both of which play important roles in synaptic transmission and learning/memory in the central nervous system (CNS). (3) Conclusions: These results suggest that oenothein B exerts neuroprotective effects on the CNS by not only its anti-inflammatory activity but also by enhancing neuronal signaling pathways.
Effect of Heat Resource Effectiveness Change on Rice Potential Yield in Southern China
Authors: Ye Qing , Yang Xiaoguang , Xie Wenjuan , Yao Junmeng , Cai Zhe
Published: May 2021

During the rice growing season, farmers’ decisions about cropping systems and seed varieties directly affect the utilization of heat resource, and eventually affect the potential yield. In this study, we used the hourly accumulated temperature model to calculate the available heat resource as well as the effective heat resource in southern China. We conducted a spatiotemporal analysis of the heat resource effectiveness during rice growing season and an impact assessment of heat resource effectiveness on rice potential yield and cereal yield reduction. The results showed that, during the period of 1951–2015, heat resource effectiveness generally declined in the rice cropping area of southern China. And this decrease worsened during the most recent three decades compared with the period of 1951–1980. A strong correlation was detected between heat resource effectiveness and rice potential yield in the study area. When the effective heat resource during the growing season increased by 1 °C·d, rice potential yield would increase by 14 kg ha−1. For each percentage increase in heat resource effectiveness, the rice potential yield reduction rate would go down by 0.65%. This agro-climatological study aims to offer a scientific basis for rice production decisions in southern China, such as when to plant, which varieties to choose and so on.
Study on Hull Optimization Process Considering Operational Efficiency in Waves
Authors: Kim Beom-Soo , Oh Min-Jae , Lee Jae-Hoon , Kim Yong-Hwan , Roh Myung-Il
Published: May 2021

This study investigates the optimization of the hull form of a tanker, considering the operational efficiency in waves, in accordance with the recent Energy Efficiency Design Index regulation. For this purpose, the total resistance and speed loss of the ship under representative sea conditions were minimized simultaneously. The total resistance was divided into three components: calm water resistance, added resistance due to wind, and to waves. The first two components were calculated using regression formulas, and the last component was estimated using the strip theory, far-field method, and the short-wave correction formula. Next, prismatic coefficient, waterline length, waterplane area, and flare angle were selected as design variables from the perspective of operational efficiency. The hull form was described as a combination of cross-sectional curves. A combination of the method shifting these sections in the longitudinal direction and the Free-Form Deformation method was used to deform the hull. As a result of applying the non-dominated sorting genetic algorithm to a tanker, the hull was deformed thinner and longer, and it was determined that the total resistance and speed loss were reduced by 3.58 and 10.2%, respectively. In particular, the added resistance due to waves decreased significantly compared to the calm water resistance, which implies that the present tendency differs from conventional ship design that optimizes only the calm water resistance.
Gain-Scheduled Model Predictive Control for a Commercial Vehicle Air Brake System
Authors: Hu Dawei , Li Gangyan , Deng Feng
Published: May 2021

This paper presents a control-oriented Linear Parameter-Varying (LPV) model for commercial vehicle air brake systems with the electro-pneumatic proportional valve based on the nonlinear mathematical model, a set of discrete-time linearized models at different target pressures with the q-Markov Cover system identification method. The scheduled parameters for the LPV model were the brake chamber pressure, which was controlled by the electro-pneumatic proportional valve. On the basis of the LPV model, a family of Model Predictive Control (MPC) controllers with a Kalman filter was designed at each operation point. Then, the gain-scheduled MPC was designed over the entire operating range with the switched strategy, which was validated by experimental data. Furthermore, compared with the PID controller, the performance of the system was improved with a gain-scheduled MPC controller.
Bacterial Succession Pattern during the Fermentation Process in Whole-Plant Corn Silage Processed in Different Geographical Areas of Northern China
Authors: Wang Chao , Han Hongyan , Sun Lin , Na Na , Xu Haiwen , Chang Shujuan , Jiang Yun , Xue Yanlin
Published: May 2021

Whole-plant corn silage is a predominant forage for livestock that is processed in Heilongjiang province (Daqing city and Longjiang county), Inner Mongolia Autonomous Region (Helin county and Tumet Left Banner) and Shanxi province (Taigu and Shanyin counties) of North China; it was sampled at 0, 5, 14, 45 and 90 days after ensiling. Bacterial community and fermentation quality were analysed. During fermentation, the pH was reduced to below 4.0, lactic acid increased to above 73 g/kg DM (p < 0.05) and Lactobacillus dominated the bacterial community and had a reducing abundance after 14 days. In the final silages, butyric acid was not detected, and the contents of acetic acid and ammonia nitrogen were below 35 g/kg DM and 100 g/kg total nitrogen, respectively. Compared with silages from Heilongjiang and Inner Mongolia, silages from Shanxi contained less Lactobacillus and more Leuconostoc (p < 0.05), and had a separating bacterial community from 14 to 90 days. Lactobacillus was negatively correlated with pH in all the silages (p < 0.05), and positively correlated with lactic and acetic acid in silages from Heilongjiang and Inner Mongolia (p < 0.05). The results show that the final silages had satisfactory fermentation quality. During the ensilage process, silages from Heilongjiang and Inner Mongolia had similar bacterial-succession patterns; the activity of Lactobacillus formed and maintained good fermentation quality in whole-plant corn silage.
Effects of Beam Conditions in Ground Irradiation Tests on Degradation of Photovoltaic Characteristics of Space Solar Cells
Authors: Imaizumi Mitsuru , Ohshima Takeshi , Yuri Yosuke , Suzuki Kohtaku , Ito Yoshifumi
Published: May 2021

We investigated the effects of irradiation beam conditions on the performance degradation of silicon and triple-junction solar cells for use in space. The fluence rates of electron and proton beams were varied. Degradation did not depend on the fluence rate of protons for both cells. A higher fluence rate of electrons caused greater degradation of the Si cell, but the dependence was due to the temperature increase during irradiation. Two beam-area expansion methods, defocusing and scanning, were examined for proton irradiation of various energies (50 keV–10 MeV). In comparing the output degradation from irradiation with defocused and scanned proton beams, no significant difference in degradation was found for any proton energy. We plan to reflect these findings into ISO standard of irradiation test method of space solar cells.
Weaning Away from Idolatry: Maimonides on the Purpose of Ritual Sacrifices
Authors: Klein Reuven Chaim
Published: May 2021

This essay explores Maimonides’ explanation of the Bible’s rationale behind the ritual sacrifices, namely to help wean the Jews away from idolatrous rites. After clearly elucidating Maimonides’ stance on the topic, this essay examines his view from different angles with various possible precedents in earlier rabbinic literature for such an understanding. The essay also shows why various other Jewish commentators objected to Maimonides’ understanding and how Maimonides might respond to those critiques. Additionally, this essay also situates Maimonides’ view on sacrifices within his broader worldview of the Bible’s commandments in general as serving as a counterweight to idolatrous rituals.
Institutional Religious Freedom: An Overview and Defense
Authors: Marshall Paul
Published: May 2021

The idea of institutional religious freedom has become increasingly controversial, especially in the United States, and pressure for such freedom has been growing. The notion that institutions, including commercial ones, can have religious freedom rights has been described as unprecedented. However, the notion of such religious freedom has deep historical roots in a wide range of settings, is deeply intertwined with the growth of free societies, and is tied to the nature of religions themselves. This also applies to religious commercial institutions, which are far more widespread than commonly recognized. I focus particularly on what is it about such institutions that needs protecting and emphasize that what is central is the particular practice that typifies the organization. It needs the freedom to be what it is and to live out a religious commitment. If this calling is denied or subverted, then the institution loses its raison d’être. One of the principal reasons for forbidding government discrimination on matters such as religion is precisely so that private institutions will be able to appropriately employ staff and carry out policies according to their own particular beliefs as to what supports their distinctive mission. Governmental neutrality is intended to be a foundation for a lively and diverse societal pluralism, not for society to become a mirror of the government itself.
The Carol about the Pagan Rite of Sacrifice of a Goat and Its Interpretation in Russian Scholarship of the 19th to 20th Centuries
Authors: Toporkov Andrey
Published: May 2021

In publications of Russian folklore, along with authentic texts there are a number of literary stylizations based on folklore. The article traces the history of one such pseudo-folkloric text—a carol which was first published by Ivan Petrovich Sakharov (1807 to 1863) in 1837. It has been established that this carol is a montage of two texts: the first is a carol, printed in 1817 by I.E. Sreznevsky in the Ukrainian Bulletin, and the second is a song included in the Tale of Brother Ivanushka and his Sister Alyonushka (SUS 450). Such contamination is unique and is found only in this one text, which was later reprinted many times. Taking into account Sakharov’s reputation as a falsifier of folklore, there is no reason to doubt that it was he who composed this carol; such contamination of works belonging to different folkloric genres is also characteristic of other of Sakharov’s publications. The carol that Sakharov published attracted the particular interest of researchers of Slavic mythology due to the fact that it described how an old man was going to sacrifice a goat. Several generations of historians saw in this pseudo-folkloric text a description of a ritual that pagan Slavs performed in ancient times. Considering the carol as an historical document, researchers of mythology built their interpretations based on the supposed time of its appearance, the nature of its genre, plot, and individual details. Thus, Sakharov’s pseudo-folkloric creation found an eager audience among scholars, and it stimulated their imagination in picturing the life of pagan Rus’.
A* Based Routing and Scheduling Modules for Multiple AGVs in an Industrial Scenario
Authors: Santos Joana , Rebelo Paulo M. , Rocha Luis F. , Costa Pedro , Veiga Germano
Published: May 2021

A multi-AGV based logistic system is typically associated with two fundamental problems, critical for its overall performance: the AGV’s route planning for collision and deadlock avoidance; and the task scheduling to determine which vehicle should transport which load. Several heuristic functions can be used according to the application. This paper proposes a time-based algorithm to dynamically control a fleet of Autonomous Guided Vehicles (AGVs) in an automatic warehouse scenario. Our approach includes a routing algorithm based on the A* heuristic search (TEA*—Time Enhanced A*) to generate free-collisions paths and a scheduling module to improve the results of the routing algorithm. These modules work cooperatively to provide an efficient task execution time considering as basis the routing algorithm information. Simulation experiments are presented using a typical industrial layout for 10 and 20 AGVs. Moreover, a comparison with an alternative approach from the state-of-the-art is also presented.
A Collision Avoidance Method Based on Deep Reinforcement Learning
Authors: Feng Shumin , Sebastian Bijo , Ben-Tzvi Pinhas
Published: May 2021

This paper set out to investigate the usefulness of solving collision avoidance problems with the help of deep reinforcement learning in an unknown environment, especially in compact spaces, such as a narrow corridor. This research aims to determine whether a deep reinforcement learning-based collision avoidance method is superior to the traditional methods, such as potential field-based methods and dynamic window approach. Besides, the proposed obstacle avoidance method was developed as one of the capabilities to enable each robot in a novel robotic system, namely the Self-reconfigurable and Transformable Omni-Directional Robotic Modules (STORM), to navigate intelligently and safely in an unknown environment. A well-conceived hardware and software architecture with features that enable further expansion and parallel development designed for the ongoing STORM projects is also presented in this work. A virtual STORM module with skid-steer kinematics was simulated in Gazebo to reduce the gap between the simulations and the real-world implementations. Moreover, comparisons among multiple training runs of the neural networks with different parameters related to balance the exploitation and exploration during the training process, as well as tests and experiments conducted in both simulation and real-world, are presented in detail. Directions for future research are also provided in the paper.