bluuebunny/crossref_metadata_2025 huggingface dataset:
CLINICAL AND LABORATORY PREDICTORS OF RAPID PROGRESSION OF PARKINSON’S DISEASE
Authors:   Belarusian Medical Academy of Postgraduate Education, A. V. Boika
Published: May 2023

In Parkinson's disease (PD), several types of progression are conditionally distinguished. Determination of reliable criteria for identifying patients with a rapid type of PD progression in the early stages of the disease will allow us to begin the development of therapy aimed at inhibiting its development. The aim of the study was to determine the clinical and laboratory predictors of the rapid type of PD progression in the Belarusian cohort of patients. Patients with PD underwent a general somatic and neurological examination. Non-motor symptoms were assessed by completing the appropriate scales. Laboratory studies included the determination of antibodies to α-synuclein, the study of the levels of cortisol, IL-1β and IL-10, the calculation of the albumin coefficient (Qalb). Longitudinal study with three groups: 1) rapidly progressive type of PD, 2) slowly progressive, and 3) indeterminate. Candidate predictors were obtained by comparing clinical and laboratory parameters of patients with fast or slow types of PD progression. During dynamic monitoring of patients with an indeterminate type of progression, the sensitivity and specificity of predictors were determined. 113 people with PD: group 1 – 32 patients, group 2 – 26, group 3 – 55. Threshold values of indicators were obtained by comparing the clinical and laboratory characteristics of groups 1 and 2 by the Mann-Whitney method and then by ROC analysis to determine the probability of a fast type progression : Qalb less than 83.95, antibodies to α-synuclein in serum more than 4.11 ng/ml, MoCA less than 26 points. Depending on these indicators, patients of group 3 were divided into 2 subgroups: 3a) "possibly rapidly progressive" course (n = 21) and 3b) "possibly slowly progressive" course of PD (n = 34). In 16 (76%) patients from group 3a, the rapid type of progression was confirmed. In 28 (82%) patients from group 3b, a slow type of progression was confirmed. The obtained results testify to the high sensitivity and specificity of the indicators. Further research is needed to develop therapies that change the course of PD.
ANTITHROMBOTIC THERAPY TODAY. The report 1
Authors:   Belarusian State Medical University, Y. L. Zhuravkov , А. А. Koroleva ,   Belarusian Medical Academy of Postgraduate Education, A. Y. Zhuravkovа ,   Belarusian State Medical University
Published: May 2023

By the WHO data, cardiovascular diseases are the most common causes of death all over the world, thus more four of five death cases from cardiovascular diseases occur as a result of an infarct and a stroke and has premature character. One of the reasons of development of these diseases is the thrombosis, i.e. formation of potentially lethal thrombs in vessels. Therefore working out and application antithrombotic agents is priority in medicine. This short review is dedicated to these drugs.
APPROACHES TO ORIENTATION OF HIGH RESOLUTION TOMOGRAPHIC 3D RECONSTRUCTION OF TEETH IN METRIC STUDIES
Authors: Gaboutchian A. V. , Knyaz V. A. , Simonyan H. Y. , Vasilyev S. V. , Korost D. V. , Stepanov N. V. , Petrosyan G. R. , Emelyanov A. V.
Published: May 2023

Abstract. Metric studies of teeth is a rapidly developing direction in odontological research, which is supported by means of corresponding imaging techniques for obtaining detailed digital reconstructions, and by application of image analysis methods. The current article presents methodological extension of teeth 3D models’ orientation tactics, which have been used in measurement techniques in dental, palaeoanthropological and palaeontological studies. Today image analysis has sufficient potential to perform orientation of teeth on the bases of their natural features; at the same time teeth possesses all necessary morphological structures for performing orientation on 3D reconstructions obtained by means of widely used today imaging techniques. Our aim is in providing an approach to orientation of teeth for its further use in morphologically relevant, accurate and applicable for various types of research, measurement techniques. The palaeoanthropological material presented in this paper, on which the proposed technique has been tested, is from territories of European part of Russian Federation and Republic of Armenia; it has been classified as related to the Middle Bronze Age, and is planned to be studied in a wider scope in the future. X-ray micro-focus tomography has been used for obtaining reconstructions of lower molars, which were segmented from semi-mandible 3D models. These teeth were used for setting vertical axis direction by means of surface curvature analysis and calculations based on points’ coordinates, which delineate functionally and morphologically important parts of teeth. This approach to accurate and morphologically relevant orientation of the studied teeth uses more than one structure at a time for choosing correct orientation according to aims of research and features of the studied material. This provides the proposed technique necessary potential to be applied for measurements of teeth and studies of their functional changes.
Multiple adenomas of the thyroid gland in an African green monkey (Chlorocebus aethiops)
Authors: Plesker Roland , Köhler Kernt
Published: May 2023

Abstract. Two cystadenomas and one solid adenoma of the thyroid gland in a 27-year-old female African green monkey (Chlorocebus aethiops) are described here. Histologically, the solid
adenoma was classified as a well-defined solid follicular adenoma of
microfollicular type. The solid adenoma was positive for thyroglobulin in
immunohistochemistry staining, whereas the cystadenomas stained positive for both thyroglobulin and calcitonin. No evidence of excess hormone production related to the tumor presence was detected.
Geometry and topology of a Polish Outer Carpathian digital-elevation-model-interpreted lineament network in the context of regional tectonics
Authors: Kania Maciej , Szczęch Mateusz
Published: May 2023

Abstract. The Polish part of the Western Outer Carpathian lineament network was analysed based on the Global Multi-resolution Terrain Elevation Data 2010 (GMTED2010) digital elevation
model. Lineaments were identified in the visual screening of the hillshade
model. To the best of our knowledge, no one has studied the geometrical
properties of the network in relation to the topological ones. The
NetworkGT QGIS toolbox was applied to identify the nodes and branches of the
network as well as to calculate the topology parameters. Our aim was to
find differences between the western and eastern parts of the Western Outer
Carpathians; therefore, the analyses were carried out in six sectors chosen
based on the geographical subdivision in the geological context: three in
the north, mainly the Silesian unit, and three in the south, mainly the
Magura unit. We found general agreement of the identified network with the
photo-lineament map; however, some of the photo-lineaments are not confirmed
by a digital elevation model (DEM). We found that the topological parameters
of the networks change from west to east but not from north to south. There
are areas of increased interconnectivity, especially the Nowy Sącz
Basin, where the lineament network may reflect a complicated system of
cross-cutting, deep-rooted fault zones in the basement.
Exploring Generational Differences in Attitudes towards SOPs during Covid-19: A Smart Lockdown Case Study
Authors: Alvi Mobashira , Ehsan Nadeem
Published: May 2023

In Pakistan, government efforts to stem the spread of COVID-19 met with resistance due to the country's preexisting social, political, economic, and cultural conditions. The preceding pandemic shows that generational attitudes, social norms, and cultural practices can hinder the control of COVID-19. Therefore, the purpose of this study was to investigate the generational knowledge of COVID-19 and its openness to preventative measures to better comprehend the generational differences that exist with regard to the COVID-19 pandemic. Purposive sampling was used in our qualitative exploratory research in twin cities of Pakistan, i.e., Rawalpindi and Islamabad. To learn how Pakistani generations X, Y, and Z feel about and deal with COVID-19, we conducted in-depth interviews with members of these groups. This included both young and elderly persons of both genders. Manual content analysis was used to examine the data of the present study. The purpose of this study was to investigate the generational knowledge of COVID-19 and its openness to preventative measures to better comprehend the generational differences that exist with regard to the COVID-19 pandemic. Purposive sampling was used in our qualitative exploratory research in twin cities of Pakistan, i.e., Rawalpindi and Islamabad. A total of six in-depth, face-to-face interviews were conducted and a total of six major themes emerged: (1) generational differences in knowledge and perceptions of COVID-19; (2) trusted and preferred sources of health information; (3) different generations’ reactions to the first reports of the COVID-19 pandemic; (4) generational practices to prevent exposure from COVID-19; (5) different generational beliefs about the risks of not adhering to infection control procedures; and (6) generational willingness to prevent future outbreaks. The findings of the data showed that among all generations, younger people of Generation Z, in particular, tended to disregard safety rules because they were anxious to meet their friends and go back to normal. Overall, all generations showed a positive attitude towards smart lockdown and following SOPs to help prevent themselves and their loved ones from this disease. The findings of the present study provide an early indication of how different generations feel about the pandemic threat posed by COVID-19. Besides, the goal of this study was to inform the development of national policy for coronavirus pandemic containment strategies. Knowing how people feel about the pandemic and containment measures, in particular, would help policymakers devise measures that are more likely to be followed, so slowing the spread of the virus.
Preservice Teachers’ Reflections on the Use of Visual Supports to Improve Mathematics Pedagogy
Authors: An Song , Tillman Daniel , Smith Karime , Hachey Alyse
Published: May 2023

This case study inspected mathematical learning opportunities that employed the results from the participating preservice teachers’ (n=75) original visual arts creation process. Data obtained during this study provided empirical evidence for the educational viability of employing original Mondrian-style rectangle sets as a context for generating authentic mathematics inquiry opportunities. The participating preservice teachers generally indicated that through the process of creating their Mondrian-style rectangle sets and exploring the mathematical patterns within their works, such as the presence of fractions and ratios, they were able to develop an improved understanding of the pedagogy for teaching these mathematics concepts. The findings from this study suggest that both mathematics teachers and mathematics teacher educators might better serve their students by including more visual supports when teaching mathematics concepts.
Briefly Recalling Some Antecedents of Standards-Based Reform and Standardized Assessment in American Mathematics Education
Authors: Darrow, Jr. Brian
Published: May 2023

Developing and Supporting Teachers' Mathematical Pedagogy
Notes from the Field Preface Spring 2023
Authors: Mei Baldwin , Yamamoto Kaori
Published: May 2023

Developing and Supporting Teachers' Mathematical Pedagogy
Đánh giá đáp ứng hoá xạ trị đồng thời ung thư vòm mũi họng tại Bệnh viện Tai Mũi Họng Trung ương
Authors: Trung Nguyễn Quang
Published: May 2023

Mục tiêu: Đánh giá đáp ứng hoá xạ trị đồng thời ung thư vòm mũi họng tại Bệnh viện Tai Mũi Họng Trung ương.  Đối tượng và phương pháp: Nghiên cứu hồi cứu có theo dõi trên 50 bệnh nhân ung thư vòm họng được hóa xạ trị đồng thời tại Bệnh viện Tai Mũi Họng Trung ương. Thời gian điều trị từ năm 2019 đến năm 2022. Kết quả: Tỷ lệ đáp ứng hoàn toàn chung là 92%; đáp ứng hoàn toàn tại u là 96%; đáp ứng hoàn toàn tại hạch là 95%. Các biến chứng cấp và mạn chủ yếu ở mức độ 2. Kết luận: Tỷ lệ đáp ứng chung điều trị hóa xạ trị ung thư vòm họng cao; tuy nhiên thời gian theo dõi chưa dài nên chưa đánh giá được tỷ lệ tái phát, di căn sau điều trị.
Bước đầu đánh giá mối liên quan giữa nồng độ Cyfra 21-1 và tiên lượng sống thêm ở bệnh nhân ung thư phổi không tế bào nhỏ giai đoạn sớm được điều trị bằng xạ trị lập thể định vị thân
Authors: Luận Phạm Văn
Published: May 2023

Mục tiêu: Đánh giá mối liên quan giữa Cyfra 21-1 và thời gian sống thêm ở bệnh nhân ung thư phổi không tế bào nhỏ giai đoạn sớm được SBRT. Đối tượng và phương pháp: Nghiên cứu tiến cứu, theo dõi dọc 32 bệnh nhân ung thư phổi không tế bào nhỏ giai đoạn T1-T2aN0M0 với u phổi ngoại vi, được SBRT và đánh giá thời gian sống thêm từ tháng 01/2015 đến 11/2021. Mối liên quan với thời gian sống thêm (PFS và OS) của các đặc điểm lâm sàng, cận lâm sàng được phân tích đa biến. Kết quả: Trung vị tuổi là 67 tuổi, có 35,5% bệnh nhân tăng CEA và 22,6% bệnh nhân tăng Cyfra 21-1 trước điều tri. Có mối tương quan thuận, mức độ trung bình, có ý nghĩa thống kê giữa nồng độ Cyfra 21-1 và kích thước của khối u, với hệ số tương quan r = 0,4, p=0,024. Nồng độ Cyfra 21-1 trước điều trị thấp làm giảm nguy cơ bệnh tiến triển 44%, p=0,01. Ngược lại, nồng độ Cyfra 21-1 sau điều trị cao làm tăng nguy cơ tiến triển bệnh lên 1,6 lần, p=0,016. Nồng độ Cyfra 21-1 sau 3 tháng tăng làm tăng nguy cơ tử vong lên 2,9 lần với p=0,005.  Kết luận: Có mối liên quan giữa nồng độ Cyfra 21-1 trước điều trị với PFS, trong khi đó, Cyfra 21-1 sau 3 tháng điều trị liên quan với cả PFS và OS ở bệnh nhân ung thư phổi không tế bào nhỏ giai đoạn sớm được SBRT.
Đánh giá phân bố liều tới các vùng thể tích của các kế hoạch xạ trị VMAT sử dụng chùm tia 6MV, 6FFF, 10MV và 10FFF trong xạ trị ung thư cổ tử cung tại Bệnh viện K
Authors: Sơn Ngô Tuấn
Published: May 2023

Mục tiêu: Đánh giá sự phân bố liều lượng xạ trị của các kế hoạch xạ trị VMAT sử dụng chùm tia có bộ lọc phẳng FF và không có bộ lọc phẳng FFF với năng lượng 6MV và 10MV trong điều trị ung thư cổ tử cung. Đối tượng và phương pháp: Nghiên cứu mô tả trên tổng số 15 bệnh nhân ung thư cổ tử cung có chỉ định điều trị xạ trị toàn khung chậu với liều 45 Gy trong 25 buổi. Lập các kế hoạch xạ trị VMAT sử dụng chùm tia 6FFF, 10MV, 10FFF. Các kế hoạch được lập có cùng mức năng lượng thì sử dụng các hàm tối ưu hóa và điều kiện giàng buộc về phân bố liều giống nhau. Tiến hành đánh giá các kế hoạch xạ trị thông qua biểu đồ liều - thể tích DVH, các chỉ số đồng dạng phân bố liều CI, chỉ số đồng nhất liều HI, số MU, thời gian phát tia BOT và liều lượng tới cơ quan lành OARs. Kết quả: Nghiên cứu cho thấy mức độ tương đồng về độ bao phủ liều tới vùng thể tích PTV đối với các mức năng lượng. Giá trị liều trung bình của PTV lần lượt là 4409,81 ± 29,94cGy; 4407,96 ± 25,92cGy; 4409,53 ± 26,24cGy và 4411,90 ± 26,35cGy đối với các nhóm kế hoạch 6MV, 6FFF, 10MV và 10FFF. Đối với sự đồng nhất giữa kế hoạch cũng cho thấy có sự tương đồng, chỉ số đồng nhất HI và đồng dạng phân bố liều CI trung bình lần lượt là 0,88 và 0,87. Tuy nhiên, các kế hoạch sử dụng chùm tia FFF cho thể tích nhận liều thấp của mô lành thấp hơn và có ý nghĩa thống kê so với các kế hoạch sử dụng chùm tia FF. Số MU của các kế hoạch sử dụng chùm tia FFF (trung bình 1027,87 ± 128,13MU và 1141,22 ± 159,30MU lần lượt của nhóm kế hoạch 6FFF và 10FFF) nhiều hơn so với kế hoạch sử dụng chùm tia FF (trung bình 803,14 ± 103,09 MU và 737,88 ± 71,34 MU lần lượt của nhóm kế hoạch 6MV và 10MV) nhưng thời gian phát tia BOT ngắn hơn. Thời gian phát tia trung bình của nhóm kế hoạch 6MV, 10MV lần lượt là 96,38 ± 12,36 và 88,55 ± 8,56 giây. Thời gian phát tia của nhóm kế hoạch 6FFF, 10FFF chỉ còn 51,39 ± 6,41 và 34,24 ± 4,78 giây. Kết luận: Các kế hoạch xạ trị kỹ thuật VMAT cho ung thư cổ tử cung sử dụng chùm tia 6MV, 6FFF, 10MV và 10FFF đều đáp ứng các tiêu chí đánh giá kế hoạch. Phân bố liều tới các vùng thể tích không có nhiều sự khác biệt giữa các kế hoạch được khảo sát, nhưng với các kế hoạch sử dụng chùm tia FFF thời gian phát tia giảm đáng kể.
Đánh giá sự thay đổi chỉ số chất lượng kế hoạch điều trị đối với mô hình tính liều xây dựng riêng cho xạ phẫu bằng bộ chuẩn trực đa lá
Authors: Chí Đỗ Đức
Published: May 2023

Mục tiêu: Đánh giá sự thay đổi về chất lượng kế hoạch điều trị khi sử dụng mô hình tính liều riêng tự xây dựng sAXB (specific Acuros-XB) cho kỹ thuật xạ phẫu bằng bộ chuẩn trực đa lá so với sử dụng mô hình tính liều mục đích chung AXB. Đối tượng và phương pháp: Mô hình tính liều sAXB cho máy TruebeamSTx (Varian) đã được kiểm định độc lập bởi các phòng thí nghiệm quốc tế MD Anderson Dosimetry Laboratory (Texas, Houston, USA) và Seiberdorf Dosimetry Laboratory (Vienna, Áo) theo dự án IAEA CRP E24022. Phân bố liều được tính bằng mô hình AXB, sau đó tính lại với sAXB trên dữ liệu hình ảnh cắt lớp vi tính (CLVT) của mô hình (phantom) và của 13 bệnh nhân (BN), thực hiện trên cả 2 loại chùm tia photon  6MV-WFF (có lọc phẳng) và 6 MV-FFF (không lọc phẳng). Chất lượng kế hoạch điều trị được so sánh thông qua các chỉ số đánh giá độ trùng khớp phân bố liều đối với thể tích điều trị (CN, COIN), độ đồng nhất phân bố liều trong thể tích điều trị (HI), độ bao phủ liều chỉ định đối với thể tích điều trị (CQ) và liều trung bình trong thể tích điều trị Dmean so với liều chỉ định. Kết quả: Đối với chùm tia 6 MV-WFF, độ sai lệch của HI, CQ, CN và Dmean giữa AXB và sAXB lần lượt nằm trong phạm vi 2,5% ÷ 14%, 3,6% ÷ 14,9%, -9,5% ÷ -59,5%, 3,0% ÷ 14% khi đường kính thể tích điều trị trong phantom giảm từ 4cm-0,5cm. Đối với chùm tia 6MV-WFF, tương tự, độ sai lệch của HI, CQ, CN và Dmean giữa AXB và sAXB lần lượt là 3,4% ÷ 18,4%, 3,8% ÷ 19,2%, -9,3% ÷ -63,7%, 3,2% ÷ 19,2%. Trên dữ liệu của 13 BN, độ chênh lệch về giá trị trung bình của các chỉ số HI, CQ, CN, COIN, Dmean giữa sAXB với AXB lần lượt là -2,7%, -1%, -5,0%, -5,0%, -2,0% cho chùm tia 6MV-FFF, và 1,9%, 5,7%, 3,2%, 3,2%, 2,5% cho chùm tia 6 MV-WFF. Kết luận: Có sự khác nhau đáng kể về giá trị các chỉ số chất lượng kế hoạch điều trị giữa hai mô hình tính liều mục đích chung và mô hình tính liều riêng cho xạ phẫu, đặc biệt là đối với các thể tích điều trị có đường kính nhỏ hơn 4cm.
Bệnh nhân sống hơn 5 năm sau hóa xạ trị ung thư vòm họng: Chất lượng cuộc sống và ảnh hưởng của ù tai mạn tính
Authors: Hùng Trần
Published: May 2023

Mục tiêu: Ghi nhận chất lượng cuộc sống và ù tai mạn tính trên người sống sau hóa xạ trị ung thư vòm họng có sống thêm không bệnh từ 5 năm trở lên. Phân tích mối liên quan giữa ù tai mạn tính với chất lượng cuộc sống ở nhóm trên. Đối tượng và phương pháp: Nghiên cứu mô tả các ca ung thư vòm họng giai đoạn II-IVB (AJCC7th) được hóa xạ trị tại bệnh viện K từ năm 2010-2013 có sống thêm không bệnh từ 5 năm trở lên. Ghi nhận chất lượng cuộc sống và ù tai mạn tính (theo CTCAE v4.03). Đánh giá tác động của ù tai mạn tính với chất lượng cuộc sống bằng hệ số ảnh hưởng Cohen D. Kết quả: Từ 109 ca cho thấy: Điểm trung bình về chất lượng cuộc sống: Chất lượng cuộc sống toàn cầu đạt trung bình 62,9 điểm. Về điểm trung bình các chức năng, chức năng thể chất: 83,7 điểm, chức năng vai trò: 78,6 điểm; chức năng cảm xúc: 75,4 điểm; chức năng nhận thức: 78,1 điểm; chức năng xã hội: 65,4 điểm. Ù tai độ 3 chiếm 8,3%.               Ù tai độ 3 có điểm trung bình chất lượng cuộc sống khác biệt lớn, tính theo Cohen’s D, với điểm trung bình chất lượng cuộc sống ở người độ 0 trên tất cả các mục của thang đo về chất lượng cuộc sống. Kết luận: Ù tai mạn tính độ 3 tác động lớn đến tất cả các điểm trung bình trong thang đo về chất lượng cuộc sống
Effect of Aerobic Training on Maximum Voluntary Ventilation in Physically Inactive Young Adults
Authors: Sardeshmukh Pritish , Gunjal Sambhaji
Published: May 2023

Background: This study investigated the relationship between aerobic activity and pulmonary function in healthy young people. Sedentism and lack of physical fitness are two major risk factors for cardiovascular disease and other causes of morbidity and mortality. Exploration of the link between aerobic exercise and pulmonary function will help to understand how aerobic exercise improves patients' quality of life and establish a more reliable means of measuring rehabilitation results.
Methods: This research has a sample size of 40 people. The participants' approval will be obtained, and those wanting to engage in the study will be chosen. A maximal voluntary ventilation (MVV) pre-analysis will be done prior to intervention. The FITT approach will be used for 4 weeks of aerobic muscle training. After four weeks of aerobic activity, the maximum voluntary ventilation (MVV) will be tested again. The data from before and after the MVV will then be analysed.
Result: The pre intervention mean of maximum voluntary ventilation was 108.37±7.97 in litre and 71.2±3.48 in litre, with a mean difference of 24.00% predicted. The post intervention mean was 132.42±13.48, with a P value of p<0.0001 and a t value of 13.97, indicating a significant improvement after 4 weeks of intervention.
Conclusion: The Present Study Concluded That 4 Weeks of Aerobic Training Improves Endurance of Respiratory Muscles, Respiratory Muscle Performance and Maximum Voluntary Ventilation in Young Adults.

Key words: Aerobic Training, Maximum voluntary ventilation,
Effect of Eye Movement with PNF Neck Movement on Balance and Functional Mobility in Subacute Stroke Patients
Authors: Thorawade Shweta , Solankhi Chintan
Published: May 2023

BACKGROUND­: Stroke is the leading cause of disability in adults and third leading cause of death. individuals with stroke experience balance issues that limit their ability to perform a variety of daily tasks. Stroke patients have impaired oculogyration (Eye movement) and have trouble moving their eyes which is a barrier to improve functional capacity Oculogyration(Eye Movement) was found to be useful in stroke patients to improve balance. PNF enhances muscle functioning via enhancing proprioceptive sensibility, strength, flexibility and balance is improved. Subacute phase of stroke lasts for 7 days to 3 months during which majority of changes happen, very few studies have seen the effect of eye movement with PNF neck movement on balance and functional mobility in this population so this study aimed to find out the effect of eye movement with PNF neck movement on balance and functional mobility in patients with subacute phase of stroke.
PURPOSE: To evaluate the effects of eye movement with PNF neck movement on balance and functional mobility in subacute phase of stroke patients.
METHODOLOGY: A total of 38 subjects was divided into two groups according to inclusion, exclusion criteria. Pre intervension assessment was done using berg balance scale and timed up and go test. Experimental group was given eye movement with PNF Neck movement along with conventional exercises. Control group performed conventional treatment. The protocol was given for 60 min. for 3 times weekly for 8 weeks for both the groups.
RESULTS: Statistical Analysis was done using paired t test. Based on the results of the test analysis at 5% significance level ,there is a significant statistical reliable difference between the pre and post treatment values with p-value less than the 5 % significance level (< 0.05) in study and therefore it justifies the improvement in health outcome post intervention.
CONCLUSION: The present study concluded that oculogyration (Eye Movement) and neck movement by PNF proved to be beneficial for improving balance and functional mobility of subacute stroke patients.

Key words: Balance, eye movements, Functional mobility, PNF neck movement, Subacute
An Acoustic Analysis on Voice Changes in Adults and Geriatrics
Authors: S Keerthiga , Shetty Rohila
Published: May 2023

Objective: This study has established the acoustic analyses on adults and geriatrics in both male and female populations. And to compare the acoustic analyses of both male and female populations Method: Participants were 118 male and female between the age range of 30 - 60 years, without the signs and symptoms of vocal problems; Praat (6.1.16 version); Vowels /a/ /i/ and /u/.
Result: There is no significant difference (p > 0.05) for fundamental frequency (F0), harmonic to noise ratio (HNR), Jitter and Shimmer across the selected age groups (30-39; 40-49; 50-60). Gender comparison of voice characteristics shows high significant difference (p< 0.01) in fundamental frequency (F0). Whereas no difference or change in the score were noted for harmonics to noise ratio, jitter and shimmer.
Conclusion: This study, like other investigations, supports the assumption that the fundamental frequency of males increases with age. The female fundamental frequency decreases with age. The male and female voice have no significant difference among the chosen age group in statistical analysis.

Key words: [Voice, Elderly Voice, Geriatric Voice, Presbyphonia, Voice change, Male and Female Voice]
A Retrospective Observational Study on Impact of Medication Errors and Its Severity in a Tertiary Care Teaching Hospital in India
Authors: Sasmal Abhijit , Arora Pankaj , Roy Arpan Dutta
Published: May 2023

To explore and estimate the frequency of medication error, a study conducted in a tertiary care teaching hospital of East India. The medication error can be divided into Prescribing errors, Dispatching Error, Drug Administration Errors, and Indenting Errors. The purpose of this study is to determine the prevalence and nature of medication errors; to explore the causes and to study corrective actions for such medication error. Identifying and evaluating the failures of medication errors and its severity analysis in a Tertiary care teaching hospital, Kolkata and suggesting solutions on reducing medication errors. It is a prospective study of patients receiving medication during treatment. The techniques that were used to identify the medication errors the study was carried out in a Tertiary Care 320 bedded Teaching hospital at Kolkata. Data was taken from Medication Error reporting form and medicine card of patients. Proper monitoring and capturing of medication error data has been initiated. Staff has been counselled and sensitized regarding safe medication practices and proper reporting of medication errors. Regular training on medication error has been conducted by Clinical Pharmacy Department, which improve the knowledge of monitoring, capturing, reporting and prevention of medication errors by the physicians, nurses, and clinical pharmacist.

Key words: Medication errors, Administration errors, Medication Safety, Adverse drug reaction, Dispensing Error, Prescription Error
Motivação organizacional na administração pública: um estudo de caso na Secretária de Saúde de Serra Branca - PB.
Authors:   , Amorim Albino Fabíola
Published: May 2023

A motivação tem se tornado um tema extremamente importante nas administrações públicas ou privadas, bem como a gestão de pessoas para a qualificação e busca de resultados satisfatórios vinculados ao bem estar dos funcionários e a manutenção das organizações. Manter o colaborador do serviço publico motivado no decorrer do tempo, esse e o maior desafio para a gestão. Esse trabalho objetiva analisar o nível de motivação dos funcionários do setor administrativo da Secretaria de Saúde da Prefeitura Municipal de Serra Branca- PB. Quanto a metodologia de pesquisa, esse estudo de caso tem caráter exploratório-descritivo, utilizando como técnica de coleta de dados a pesquisa bibliográfica, a observação não participante e a aplicação de um questionário com servidores públicos da secretaria municipal de saúde de Serra Branca-PB. Os resultados apontam que os fatores de motivação para o trabalho mais evidentes são os de "satisfação com o desenvolvimento de carreira", no que tange as oportunidades criadas para o desenvolvimento de novas competências, bem como as "ações de formação", "a satisfação com a gestão" e "o sistema de gestão", ou seja, a forma como as organizações organizam e recompensam os esforços individuais e coletivos, a postura organizacional face as mudanças e a modernização, bem como a satisfação com as condições de trabalho.
Gestão dos resíduos sólidos no Cariri da Paraíba.
Authors:   , Angelo do Nascimento Genildo
Published: May 2023

A gestão dos resíduos sólidos tem se apresentado como um dos maiores desafios da sociedade moderna. O Governo Federal, por meio da Política Nacional de Resíduos Sólidos (PNRS), tem buscado partilhar com os demais entes da federação a responsabilidade pelo planejamento das políticas públicas locais, cabendo assim aos gestores municipais, a responsabilidade pela condução de seu município no campo ambiental. O estudo tem por objetivo conhecer a Gestão dos Resíduos Sólidos nos municípios do Cariri Ocidental da Paraíba. Essa Microregião, tem se mostrado uma área onde a PNRS não conseguiu sua plena operacionalização, já que a presença dos lixões nos municípios e a ausência do Plano Municipal de Resíduos Sólidos à coloca em uma corrida contra o tempo, no intuito de alcançar as metas propostas pela PNRS até 2014. A pesquisa possui características descritivas e exploratórias, com a utilização de dados fornecidos pelas próprias prefeituras e dados disponibilizados em sites especializados na temática. Diante da realidade encontrada, concluiu-se que a gestão dos resíduos sólidos no Cariri Ocidental da Paraíba, têm se apresentado ineficiente, e há necessidade de implementação urgente de melhorias nessa área, sendo necessário aos gestores a compreensão de que o meio ambiente é tão importante quanto a educação ou a saúde para os municípios.
Comparison of Biological Activities and Bioactive Components of Seed, Leaf, and Blossom Parts of Camellia sinensis (L.) Kuntze and Commercial Black Tea
Authors: mer ERT RK mer ERT RK , Elif L Elif L , Melek OL AYVAZ and Emine BA DATLI Melek OL AYVAZ and Emine BA DATLI
Published: May 2023

In this study, bioactive properties and GC-MS analyses of the Camellia sinensis (seed, leaf, and blossom parts) and commercial black tea extracts were compared. The total phenolic content (TPC) and antioxidant and antimicrobial activities of extracts were determined. The gas Chromatography-Mass Spectrometry (GC-MS) technique was used to identify the major bioactive compounds in extracts. The TPC and antioxidant activity values of the alcohol extract prepared from the leaf part of the C. sinensis are higher than the other extracts. There was a strong correlation between total phenolic content and antioxidant amount among the ethanol extracts of C. sinensis. In antimicrobial evaluation, the ethanol extracts showed more activity; the ethanolic extract of C. sinensis seeds was the most effective. GC-MS results indicated various organic compounds in the C. sinensis extracts, mainly saturated and unsaturated aromatic esters, aromatic alcohols, some cyclic structures, aromatic amine, and boranic esters with different therapeutic activities. The black tea extracts exhibited a more straightforward variety of bio components as aromatic esters and boranic ester. According to the obtained results, C. sinensis and black tea extracts would exert several beneficial effects by their biological activities thanks to the possible synergistic effect of chemical contents detected by GC-MS analysis. However, GC-MS results indicated that the black tea sample had much fewer bioconstituents than fresh C. sinensis plant samples.
Calculated Estimation of the Displacement Current Density and its Influence on Electromagnetic Processes in a Metallic Conductor with an Alternating Current
Authors: Baranov M. I.
Published: May 2023

The results of approximate calculations of the density δs(t) of the displacement current is(t) and the estimation of its influence on electromagnetic processes in the homogeneous non-magnetic metals (alloys) of a continuous cylindrical conductor of finite sizes (radius r0 and length l0>>r0) with an electric variable (pulse) axial current i0(t) of different amplitude and temporal parameters. The theoretical data obtained for the quantized (discrete) spatio-temporal distributions of standing longitudinal waves (half waves) of the displacement current is(t) at density δs(t) in the indicated conductor leads to the following conclusion. In the electrodynamic calculations of variable (pulse) electromagnetic processes that occur both in this conductor and in an electric circuit in it, it is possible to neglect the influence of longitudinal waves (half waves) of the displacement current is(t) at density δs(t) and of the displacement current is(t) itself at the practical field calculations. It is found that the waves (half waves) of the displacement current is(t) at density δs(t) and of the displacement current is(t) maintain solenoidality of the total electric current of ii(t) = i0(t)+is(t) in the conductor and its circuit. The calculations has shown that the displacement current is(t) and its density δs(t) in a non-magnetic metal (alloy) of the studied conductor do not lead to thermal (joule) energy losses.
Penggunaan Aplikasi Wordwall Pada Pembelajaran Sejarah Di SMA Negeri 5 Pontianak
Authors: Amalia Hasanah Baiyeni , Firmansyah Andang , Firmansyah Haris
Published: May 2023

Dampak dari pesatnya kemajuan teknologi tidak dipungkiri banyak pula berbagai media pembelajaran yang berbasis teknologi tercipta. Media pembelajaran memiliki banyak manfaat, salah satunya sebagai alat untuk menyampaikan tujuan pembelajaran. Terlebih lagi bagi pembelajaran sejarah, sudah tak asing lagi banyak peserta didik yang kurang berminat dengan pembelajaran sejarah. Sebab pembelajaran sejarah berisikan berbagai macam peristiwa yang mengharuskan peserta didik mengingat seluruh hal tersebut. Maka dari itu penggunaan media sangat dibutuhkan pada pembelajaran sejarah. Tujuan penelitian adalah untuk mendeskripsikan penggunaan aplikasi Wordwall pada pembelajaran sejarah di kelas XI SMAN 5 Pontianak. Metode penelitian menggunakan kualitatif deskriptif. Lokasi penelitian berada di SMAN 5 Pontianak. Adapun teknik pengumpulan data menggunakan wawancara, observasi dan dokumentasi. Sumber informan penelitian yakni guru sejarah dan peserta didik kelas XI SMAN 5 Pontianak. Hasil penelitian yang diperoleh adalah penggunaan aplikasi Wordwall dapat membantu guru menyampaikan materi-materi sejarah yang sulit dimengerti oleh peserta didik. Sedangkan bagi peserta didik belajar sejarah menggunakan aplikasi Wordwall merupakan pengalaman yang baru dan menyenangkan, sehingga peserta didik lebih berminat dan aktif selama proses pembelajaran sejarah.

Kata Kunci: Media Pembelajaran, Pembelajaran Sejarah, Wordwall
SWITCH DEVICES ON STEPPER MOTORS WITH MICROCONTROLLER CONTROL
Authors: KOZLOVSKY D. , MOLODECHKINA T.
Published: May 2023

A combined instrument panel is proposed, which is included in the laboratory stand for simulating the operation

mode of pointer devices. The main functions performed by the control unit of the laboratory bench are given,

the design features are especially noted. The choice of the Arduino IDE software environment for software development

is substantiated. The selection of the library used to combine between the Arduino board and the components

of the stand has been made. Software for the laboratory control unit has been developed and studied.
CREATION OF ELECTRONIC EDUCATIONAL AND METHODOLOGICAL COMPLEXES
WITH THE HELP OF THE ONTOLOGICAL APPROACH
Authors: OSKIN A. , KONAPLEVA G. , TAVGEN T. , GROPPEN V.
Published: May 2023

The article discusses the possibilities of ontological modeling and its application for creating knowledge

bases of electronic educational and methodological complexes. It is shown that with the help of ontological modeling

it is possible to define a subject area, develop a conceptual model, create and fill an ontology with data, and

finally put the ontology into action. The toolkit of ontological modeling and its possibilities for creating knowledge

bases of electronic teaching and learning kits are considered. It is shown that the Zettelkasten technology and the

Obsidian application can be used to build a working model of the knowledge base. An example of the application

of the stated methodology in the construction of the knowledge base "History of the Polotsk Cadet Corps" is given.
INDENTATION OF ELECTRON-IRRAUDED FILMS OF DIAZOQUINONE NOVOLAC
PHOTORESISTS ON SILICONE
Authors: VABISHCHEVICH S. , VABISHCHEVICH N. , BRINKEVICH D. , PROSOLOVICH V.
Published: May 2023

The strength properties of FP9120, SPR 700 and S1813 G2 SP15 diazoquinone novolac photoresist films

on silicon irradiated by 5 MeV electrons with a fluence of 3 1016 cm-2 were studied by indentation. Misprints of

the microindenter in films of diazaquinone novolac photoresist are barrel-shaped, which indicates the presence

of tensile stresses that form during film drying. A destruction zone with radial and lateral cracks was observed

around the indenter prints, forming a pattern in the form of "butterflies". It has been established that during longterm

storage and irradiation of films of diazoquinone novolac photoresists, an increase in the values of the true

microhardness of the films takes place, which is due to the cross-linking of novolac macromolecules in the bulk

of the polymer.
Technology and Care Load in Future Hospitals
Authors: Guerrero William Javier
Published: May 2023

Recent technological progress is generating important disruptions, and healthcare is no stranger to them. Nursing is subject to technology change disruptions. It is important to reflect on the advantages and disadvantages technology brings with it and the changes it generates in care processes. If technology is only used to register information, it is perceived as a load that creates anxiety in the professionals. In this article, deep questions are made about the technology acceptance challenges in the nursing care processes, its implications on nursing responsibility, and the research opportunities for adopting new care humanized models result of technological development.
Rights without Ratification: How the US Government Found Its Way to Peace with Austria in the 1920s
Authors: Phelps Nicole M.
Published: May 2023

After the US Senate rejected the Treaty of Versailles in 1920, the US government needed to find an alternate, politically viable route to a legal termination of its state of war with Germany, Austria, and Hungary. This was necessary to reopen diplomatic and trade relations, end domestic wartime legislation in the United States, settle a range of war-induced property claims, and, in Austria, to secure a League of Nations economic restructuring plan. In the Knox-Porter Resolution, or July Resolution, Congress claimed rights based on November 1918 armistices and the subsequent Paris treaties, even as they refused to ratify those actual treaties. This resolution formed the basis of the 1921 US treaties with Austria, Hungary, and Germany. The process of settling property claims dragged on until the end of the decade. The coverage in the New York Times reveals the importance of conflicts between the executive and legislative branches, partisanship and debates over the future of US foreign policy, US politicians’ focus on Germany rather than on the particular circumstances facing Austria, and a commitment to protecting private property rights as elements that shaped and prolonged the process of reaching a US-Austrian peace.
Doğumhanede Maternal ve Neonatal Güvenliğin Önemi
Authors: YEYĞEL Çiler , DÖNMEZ Ayşegül , KILINÇ Derya
Published: May 2023

Hasta güvenliği, dünyada tüm sağlık bakım hizmetlerinin primer konuları arasında yer alan, nitelikli sağlık hizmetlerinin sunumunda vazgeçilmez ve çok önemlidir. Maternal-neonatal mortalite ve morbidite doğumdan önce, doğum anı ve doğumdan hemen sonrasıyla ilişkili küresel bir sağlık sorunudur. Anne ve yenidoğan ölümlerinin büyük çoğunluğu, etkili müdahale ve nitelikli bakım ile önlenebilir. Anne ve yenidoğan sağlığı açısından önemli bir yere sahip olan doğumhanelerde istenmeyen sonuçları önlemek için hasta güvenliği hizmet sürecinin tam ve eksiksiz olması maternal ve neonatal güvenlik açıdan büyük önem taşımaktadır. Doğum sırasında maternal ve neonatal gereksiz-zararlı uygulamaları azaltmayı, güvenli bakım için sağlık profesyoneli kapasitesinin güçlendirilmesini ve desteklenmesini, güvenli doğum için saygılı bir bakımın teşvik edilmesini, doğum anında ilaç kullanımının ve kan naklinin güvenli olarak gerçekleştirilmesini, doğumda güvenlikle ilgili durumların raporlanmasını ve analiz edilmesini hasta güvenliği başlığı altında anne ve yenidoğan güvenliği açısından hedeflenmektedir. Doğum birimindeki hizmet sağlayıcıları etkili iletişim teknikleri, holistik bakım ve ekip iş birliği, ekip arasında vaka tartışmaları ve eğitimleri, kanıta dayalı çalışmalar/rehberler, kontrol listeleri ve obstetrik alana özgü hasta güvenliği kültürü oluşturmak hasta güvenliğinin temel bileşenleridir.
Bu derlemede doğumhanelerde maternal ve neonatal uygulamalarının hasta güvenliği kapsamında değerlendirilmesine dikkat çekilmesi amaçlanmıştır.
The Beatific Vision in the Synopsis Purioris: Its Medieval Context
Authors: Seals Zachary
Published: May 2023

This article explores the background to the discussion of the beatific vision found in the Synopsis Purioris Theologiae (1625) by comparing what is found therein with several treatments of the topic by prior and contemporary theologians at the University of Leiden. This historical context reveals the distinctive contribution offered by the SPT, which primarily consists in its engagement with debates found in medieval scholasticism concerning the beatific vision. By surveying two exemplary thinkers from the medieval era, Thomas Aquinas and John Duns Scotus, in consideration with what was found in the SPT, an example is provided that displays the eclectic appropriation of medieval sources within the Reformed Orthodox tradition.
ECCLESIASTES: LIFE IN A FALLEN WORLD
Authors: Harman Allan
Published: May 2023

Review of ECCLESIASTES: LIFE IN A FALLEN WORLD By Benjamin Shaw (Edinburgh: Banner of Truth, 2008), 156pp., £5.50.ISBN: 9781848718685
WALKING IN THE ANCIENT PATHS: A Commentary on Jeremiah
Authors: Harman Allan
Published: May 2023

Review of WALKING IN THE ANCIENT PATHS: A Commentary on JeremiahBy Walter C. Kaiser Jr, with Tiberius Rata (Bellingham: Lexham Press, 2019), 633pp., US$49.99.ISBN 9781683592679
GOSPEL SHAPED MARRIAGE: Grace for Sinners to Love Like Saints
Authors: Emery Thomas
Published: May 2023

Review of GOSPEL SHAPED MARRIAGE: Grace for Sinners to Love Like SaintsBy Chad Van Dixhoorn and Emily Van Dixhoorn (Wheaton: Crossway, 2022), 160pp., US$17.99ISBN: 9781433580710
THOMAS CHALMERS AND THE STRUGGLE FOR A CHRISTIAN NATION
Authors: Harman Allan
Published: May 2023

Review of THOMAS CHALMERS AND THE STRUGGLE FOR A CHRISTIAN NATIONBy Esmond Birnie (Belfast: The Evangelical Bookshop, 2018), 224pp., £9.99. ISBN 9780952266259
Graced Exchange and Vision of God in Calvin’s Atonement Theology
Authors: Mosser Carl
Published: May 2023

John Calvin structured his soteriology and doctrine of atonement around the patristic principle of graced exchange, the idea that Christ became what we are in order to make us what he is. In them, Christ’s descent to hell and the believer’s ascent to God represent the two furthest poles of the exchange. Descent to hell and ascent to God both involve vision of God. Calvin explains descent to hell as the terror sinners experience in their souls when they sense God’s wrath and judgment. In the passion and crucifixion, Christ arraigned himself before God’s tribunal as our surety to make satisfaction. Standing in the place of the accused, he saw God as an angry judge prepared to punish sin. As a real human being with the affections and infirmities common to human nature, Christ could not help but experience terror in his soul and even fear for his own salvation. Christ willingly underwent this ordeal to prove his obedience, demonstrate his love for humanity, and secure a more lavish redemption than otherwise possible. Christ emerged from the ordeal victorious and the Father accepted his obedience as satisfaction for our sin. As a result, the redeemed are adopted as sons who will ascend to God and see him face-to-face as a propitious Father.
Communication problems at the University of Goma "UNIGOM"
Authors: Mungazi Cosmas
Published: May 2023

This practical work of the English seminary, presented in the setting of the Doctoral school of the university National Educational UPN-UNIGOM given by the Professor Ordinaire Mbukani carries on" the problems or obstacles of the communication in an academic institution ", case of the University of Goma. The choice of this academic institution is not a fact of the luck", like all communication was never at random ". Because the UNIGOM is the biggest official university that the city of Goma counts, curiously that knows several problems that affect his/her/its wanted picture by his/her/its publics.
Significaciones y prácticas en torno al trabajo de mujeres externadas de un hospital neuropsiquiátrico de la provincia de Buenos Aires, Argentina
Authors: Hartfiel María Isabel , Ardila-Gómez Sara
Published: May 2023

Introducción: El trabajo es central para la inclusión social de personas que tuvieron internaciones psiquiátricas prolongadas. Por ello es necesario generar conocimientos locales sobre estos procesos en personas que han sido externadas, como parte de la reforma de la atención en salud mental en Argentina. Así, el objetivo de este estudio fue describir las significaciones y las prácticas de mujeres que tuvieron internaciones psiquiátricas prolongadas en el Hospital “José A. Estéves” de la Provincia de Buenos Aires, Argentina, acerca de su inclusión en el mercado laboral, a partir de su externación. Materiales y Métodos: Estudio descriptivo de tipo mixto, tomando como caso al grupo de mujeres que eran acompañadas por el Programa de Rehabilitación y Externación Asistida del Hospital “José A. Estéves”, en el año 2018. Se analizaron datos cuantitativos de todo el grupo (n=69) y se realizaron entrevistas semi-estructuradas con nueve señoras. Resultados: El 74% de las mujeres realizó algún trabajo desde su externación, aunque al momento del estudio, solo el 33% lo hacía. Los trabajos que desarrollaban correspondían a niveles ocupacionales elementales o de bajo nivel de competencia, mayoritariamente en un programa asistido de trabajo. Después de la internación, los trabajos obtenidos fueron menos calificados, más informales y menos expuestos al público que los desempeñados antes de la internación. Discusión y conclusiones: La internación psiquiátrica prolongada constituye un corte significativo en la trayectoria laboral de las personas. Pese al valor de las experiencias laborales de quienes logran conseguir un trabajo tras la internación, tales experiencias no implican, mayoritariamente, avances sobre el mercado formal.
Tiempos de lectura de oraciones con lenguaje inclusivo en español: un estudio psicolingüístico
Authors: Zarwanitzer Ana , Gelormini-Lezama Carlos
Published: May 2023

Introducción: El lenguaje inclusivo se manifiesta en español en el uso de los morfemas -e y -x, en lugar del masculino genérico. Este estudio aborda el procesamiento de oraciones con lenguaje inclusivo desde la perspectiva de la psicología cognitiva experimental y con las herramientas metodológicas de la psicolingüística. Método: con un experimento de lectura a ritmo personal se examinó la diferencia en los tiempos de lectura de oraciones con masculino genérico y oraciones con lenguaje inclusivo. Participaron 69 hablantes monolingües de español rioplatense: 38 jóvenes (entre 18 y 30 años: 23 mujeres y 15 varones) y 31 adultos (entre 31 y 60 años: 12 mujeres y 19 varones). Resultados: las oraciones con lenguaje inclusivo se leyeron más lentamente que las correspondientes oraciones con masculino genérico. Crucialmente, las variables edad y género no produjeron diferencias significativas. Discusión: estos resultados sugieren que la lectura de oraciones con lenguaje inclusivo conlleva un mayor costo de procesamiento y que este cambio lingüístico se encuentra en etapas muy iniciales.