bluuebunny/crossref_metadata_2025 huggingface dataset:
Entrepreneurial Behaviour and Organisational Propensity to Innovate in a Public-Sector Context
Authors: Iliashenko Iuliia , Papagiannis Fragkoulis , Gazzola Patrizia , Cherkas Nataliia , Grechi Daniele
Published: April 2023

The importance of innovation, in both private and public entrepreneurial fields, is the basis of all companies’ strategic choices. This study examines entrepreneurship and innovation, as well as their dynamic interface in value creation, in the public sector. It explores entrepreneurial determinants for public-sector innovation, as collected from managers and employees involved in the water supply and sewage industries in Ukraine. The data, related to a sample of firms, were obtained from a twofold self-administered survey. Adopting an ordered logistic regression model to analyse the data obtained from a survey, it is found that the entrepreneurial determinants of self-awareness, knowledge-enabling and entrepreneurial orientation positively correlate with fostering innovation process. The findings reveal that entrepreneurial leadership and intrapreneurial self-efficacy are mediating determinants. Finally, the results demonstrate that intrapreneurial self-efficacy has more potential than entrepreneurial leadership to stimulate innovation at the individual level, which has both theoretical and practical implications.
Action in Complexity: Entanglement and Emergent Order in Entrepreneurship
Authors: Leong David
Published: April 2023

When properly understood in the context of entrepreneurship, entanglement explains the complex ingredients in the tangled relations required for entrepreneurial success. However, in examining entrepreneurial success, many scholars overlook a critical consideration—are the right resources (people and materials) in the right place at the right time? How do entanglement and convergence come about? This occurs when a microsystem is entangled with many fine-grained structures with different degrees of freedom, converging to generate emergence. These fine-grained structures are the heterogeneous agents with correlated histories (co-founders, financiers, suppliers, competitors, customers, employees, etc.) that are entangled with the entrepreneurs. This article explains the complex causes in the emergent order arising from several entangled dynamics among the heterogeneous agents and resources. The challenge is understanding what complex ingredients and combinations are necessary for a new emergent order that gives rise to such possibilities. Finally, such emergence arising from entanglement is discussed to explain collaboration and coevolution effects, and suggestions for future research that utilises the intended theorisations of practice are offered.
Management of Hand Screen Printing Workers Health Using Ergonomic Design Intervention
Authors: Shankar S. , Pradeep S. , Karthick J. , Naveenkumar R. , Jayaraman Srinivasan
Published: April 2023

Hand Screen Printing (HSP) is one of the dominant textile-processing industries that plays a significant role in the employment of people in and around the rural regions of the developing countries. Further, most of the HSP industries are small scale industries sector, workers are illiterate or lack work safety knowledge, also both management and workers ignore the ergonomic issues in their day to day life. Though various research groups have attempted to evaluate both qualitatively and quantitative the ergonomic issues faced by HSP workers, due to lack of direct solution to improve the HSP workers’ ergonomic environment, there is still a huge space is available for further intervention. The present study aims to redesign the squeegee frame for HSP workers and validate its effect over the workers’ health. In this study, the traditional squeegee was modified by considering the evaluated ergonomic issues. To evaluate the design intervention, ten male volunteers participated in the study and performed the HSP operation using both traditional squeegee (pre-intervention) and retrofitted squeegee (post-intervention). Further, the study population was divided into two equal group such as control group and low back pain (LBP) group. The surface Electromyogram (sEMG) signal, Rapid Entire Body Assessment (REBA) score and Borg’s scale data were collected, to assess the post intervention attempt. Result inferred that retrofitted squeegee intervention had reduced the REBA score (postural risk) by 52% and Borg’s scale by 51% (workers’ pain intensity). In addendum, sEMG study supported these findings by showing a decline in muscle fatigue for the LBP group. This study concludes that, retrofitted squeegee intervention aspect can be an effective agent to improve the ergonomic posture and reduce the musculoskeletal disorders among HSP workers and significantly increase the productive of textile industry.
Role of Spirulina in Structural Remodeling of Synapse in Telencephalon of Chronic Unpredictable Stress Model of Zebrafish
Authors: Kumar Harender , Garg Vincy , Kaur Kawalpreet , Kaur Ravneet
Published: April 2023

Background

Stress can affect the morphology and synaptic organization of the telencephalon. These structural changes at the cellular level can lead to the development of various psychopathologies.

Purpose

Given that the telencephalon plays a major role in stress responses, the current study aimed to investigate the role of Spirulina platensis as a neuroprotectant supplement in the early life of zebrafish in averting the alteration of synapse morphology in the telencephalon caused by chronic unpredictable stress (CUS) in the later stage.

Methods

5dpf larvae were divided into two groups: one group was fed with a commercial fish diet and a second group with a 1% Spirulina-supplemented diet for 90 days. After 90 days, the adult zebrafish were exposed to CUS with different chronic stressors for 15 days. The synaptic plasticity was evaluated by morphometric analysis of synapse in telencephalon of zebrafish by transmission electron microscopy.

Results

The ultrastructural study demonstrated the protective role of Spirulina in the CUS model as no significant alterations in the length of the active zone, postsynaptic density, and synaptic cleft were observed as compared to the control group in the CUS model.

Conclusion

Thus, suggesting that the Spirulina supplementation can avert the remodeling effect of stress on synapse ultrastructure.
TBL Myanmar: Understanding the Barriers to Sale of Dehumidifiers in Emerging Markets
Authors: Chhabra Sakhhi
Published: April 2023

Vipul Murarka, Executive Director of Tropical Biotechnology Ltd. (TBL), was perplexed after looking at the erratic sales of dehumidifiers over the past 3 years since he started in June 2016. Although the number of goods sold was growing until 2019, which gave a marginal increase in revenue earned, the top line was increasing at a decreasing rate, with 10% in the first year, 8% in the second year and 7% in the third year. He could not understand the reasons for these inconsistent sales despite offering quality solutions and having many satisfied clients in the past.

Given the torrential rains throughout the year in Yangon, the capital of Myanmar, a dehumidifier was an essential product for factories, yet sales were not picking up as anticipated. Dehumidifiers as an industrial product aided many manufacturing units, as they helped in controlling moisture by extracting water from the air, thus reducing humidity and preventing the growth of mildew. There were myriad manufacturing companies in Yangon because of the availability of cheap labour, yet sales for certain months were flat, with not even one sales call funnelling to final action. These lull periods made Vipul anxious and forced him to think if he had entered the wrong industry. He even thought if the first-mover advantage turned into a disadvantage for him. The initial reason he speculated about this sales barrier was the price, as it was a high-investment product for industrial buyers. However, he also posited to himself that he might not have been able to position the advantages of the product aptly in the minds of the potential buyers.

Unable to find a definitive reason for the sales barriers of the dehumidifiers, he approached his friend, Myint Than, an independent consultant and visiting faculty at an MBA institute where he taught sales and marketing strategy courses. Vipul and Myint had to find the reason for the barrier to the dehumidifier sales and eventually make a strategy to overcome these barriers for future growth before deciding the sales target for the year 2020.
Defining wellness in legal education: A reply to Kawamata
Authors: Crowe Jonathan
Published: April 2023

This article responds to Oscar Kawamata’s thought-provoking criticisms of the conception of law student well-being that I previously advocated in this journal. Kawamata argues that my objective model of well-being is unrealistic and unhelpful from his perspective as a law student, proposing instead a subjective account grounded in Buddhist philosophy. While acknowledging Kawamata’s valid concerns, I suggest that an idea of well-being with objective elements is still preferable to a purely subjective conception. Put simply, well-being does not just consist in changing your mind; sometimes, you need to change your life as well.
Veteran homelessness in Australia: What do we know? What has been done? What do we need to do?
Authors: Wallace Duncan , Hoggett Kat , Cripps Sue , Hayhurst Wendy , Klinge Nathan
Published: April 2023

Objective

We report on the extent of veteran homelessness in Australia, what has already been done to address it and what actions are recommended to further improve the response.

Conclusions

Work conducted by not-for-profit organisations and the Department of Veterans’ Affairs are outlined with positive prospects for significant coordinated action to further address the situation reported.
Fludrocortisone Plus Hydrocortisone Versus Hydrocortisone Alone as Adjunctive Therapy in Septic Shock: A Retrospective Cohort Study
Authors: Lock Ashley E. , Gutierrez G. Christina , Hand Elizabeth O. , Barthol Colleen A. , Attridge Rebecca L.
Published: April 2023

Background:

Trials evaluating hydrocortisone (HC) for septic shock are conflicting with all finding decreased time to shock reversal but few with mortality difference. Those with improved mortality included fludrocortisone (FC), but it is unknown if FC affected the outcome or is coincidental as there are no comparative data.

Objective:

The objective of this study was to determine the effectiveness and safety of FC + HC versus HC alone as adjunctive therapy in septic shock.

Methods:

A single-center, retrospective cohort study was conducted of medical intensive care unit (ICU) patients with septic shock refractory to fluids and vasopressors. Patients receiving FC + HC were compared with those receiving HC. Primary outcome was time to shock reversal. Secondary outcomes included in-hospital, 28-, and 90-day mortality; ICU and hospital length of stay (LOS); and safety.

Results:

There were 251 patients included (FC + HC, n = 114 vs HC, n = 137). There was no difference in time to shock reversal (65.2 vs 71 hours; P = 0.24). Cox proportional hazards model showed time to first corticosteroid dose, full-dose HC duration, and use of FC + HC were associated with shorter shock duration, while time to vasopressor therapy was not. However, in 2 multivariable models controlling for covariates, use of FC + HC was not an independent predictor of shock reversal at greater than 72 hours and in-hospital mortality. No differences were seen in hospital LOS or mortality. Hyperglycemia occurred more frequently with FC + HC (62.3% vs 45.6%; P = 0.01).

Conclusion and Relevance:

FC + HC was not associated with shock reversal at greater than 72 hours or decreased in-hospital mortality. These data may be useful for determining corticosteroid regimen in patients with septic shock refractory to fluids and vasopressors. Future prospective, randomized studies are needed to further evaluate the role of FC in this patient population.
Body Uneasiness, Body Figure Perception, and Body Weight: Factor Structure and Longitudinal Measurement Invariance of a Set of Attitudinal and Perceptual Body Image Assessment Tools in Adolescents
Authors: De Caro Elide Francesca , Grassi Michele , Di Blas Lisa
Published: April 2023

Body image is a multifaceted construct that includes attitudinal and perceptual components, but its attention has mainly been focused on the facet of body dissatisfaction. The present longitudinal study extended the validation of a multifacet attitudinal questionnaire, the Body Uneasiness Test (BUT), against perceptions of body shape and weight. A convenient sample of adolescents took part in a 2-year unbalanced panel study (5 waves). The participants completed the BUT questionnaire and selected their perceived actual, ideal, and reflected body figures along the Contour Drawing Rating Scale; ideal/actual and ideal/normative body mass index discrepancies were also included. After replicating the expected five-factor structure of the BUT items, results from confirmatory factor analysis revealed that the five BUT scales loaded on an attitudinal dimension, whereas the perceived body figures and the discrepancy indices were on a perceptive domain. Such a two-domain structure of body image measures showed gender and seasonal (1-year) measurement invariance, whereas longitudinal 6-month and 18-month invariance partially failed. Overall, the present findings support the validity of the Body Uneasiness Test in adolescence, further demonstrating a preliminary multidimensional structure of body image onto which attitudinal and perceptual body image-related measures were projected.
Adaptive backstepping control design for ATMD systems in nonlinear structures with nonlinear disturbance and parametric uncertainties
Authors: Ümütlü Rafet Can , Bidikli Baris , Ozturk Hasan , Pavic Aleksandar
Published: April 2023

Active tuned mass damper (ATMD) devices are recommended in various structures to reduce vibrations. The performance of the ATMD system is closely tied to the control design utilized, according to research in the literature. The designed control input will take into account as much system dynamics as possible, making it possible to use it as a generalized controller in all similar systems. Nonlinear behavior is the natural behavior of engineering structures, and in order to obtain a more realistic and high-performance ATMD system, it can be considered as an appropriate approach to design the controller by considering the structural nonlinearities. In addition, unexpected external influences and parameter uncertainties must be taken into account during control design to ensure that control systems perform successfully in similar systems in all conditions. Therefore, in this study, the nonlinear model of the multi-story building was reconstructed by adding nonlinear disturbance to represent unknown external effects. Band-limited white noise is used as a disturbance function and Gaussian white noise is added to measured states in this study. To obtain a robust controller, unknown structural parameters are compensated for by using adaptive compensation terms. With the controller design supported by the Lyapunov-based stability analysis, the stability of the vibrating structure featuring an ATMD is theoretically guaranteed while achieving the main control goal. Performance analyses of the designed controllers are carried out with simulation studies. The efficiency of the developed Lyapunov-based controller in dampening the unwanted vibrations that occurred on the building is seen in simulation results.
The Intersection of Health and Justice: An Evaluation of Mental Health First Aid Training for Justice-involved Professionals
Authors: Arazan Christine L. , Weich Leah
Published: April 2023

Where historically justice and behavioral health professionals have functioned independently in systems that often collide, the ability to provide community behavioral health training to justice involved professionals may lead to enhanced public safety and decreases in incarcerations. This study evaluated the impact of the Mental Health First Aid program completed by 85 justice professionals. Study participants completed a questionnaire before and after the training to assess the impact on knowledge, attitudes, and beliefs. Findings suggest the training reduced stigmatizing attitudes and improved participants’recognition of mental health disorders, self-confidence in providing help, and intent to help. The results of this study provide preliminary evidence supportive of justice communities investing in the Mental Health First Aid training consistent with the International Chiefs of Police Association’s commitment to the “One Mind Campaign” to ensure that justice professionals have the skills to safely and responsibly meet the needs of people with mental illness
Spaces of Displacement on the Island of Imbros/Gökçeada
Authors: Ercan Sevcan
Published: April 2023

This article investigates spaces of displacement within the context of Imbros, employing it as a case study to provide a novel perspective on the global phenomenon of displacement. Imbros/Gökçeada is a Turkish island in the Aegean Archipelago, currently inhabited by Turkish citizens from the mainland plus an indigenous community known as Rums or Asia Minor Greeks—an ethnic group who have faced waves of systematic displacement from the island during the 20th century since the demise of the Ottoman Empire. While the displacement of Imbrian Rums intensified between the period 1963 and 1980, the island simultaneously began to accommodate a growing number of Turkish residents, most of whom were emplaced by the Turkish authorities into the state-built villages on Imbros. Since the late 1990s, however, a return movement of the displaced Rum community to Imbros has gradually emerged through the revitalization of several Rum rituals on the island. As a result of these multiple temporal and spatial layers of displacement witnessed on Imbros, the question of how to better understand the phenomenon of displacement arose. To that end, the concept of positionality is deployed as a lens through which to analyze the various phases and spaces of displacement as they have occurred on Imbros itself, and from this, I produce the observation that the spatial phenomenon of displacement on Imbros is actually an entanglement of displacement, emplacement, and return (re-emplacement).
Outcomes among patients with peripheral artery disease in the Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness (ADAPTABLE) study
Authors: Weissler E Hope , Stebbins Amanda , Wruck Lisa , Muñoz Daniel , Gupta Kamal , Girotra Saket , Whittle Jeff , Benziger Catherine P , Polonsky Tamar S , Bradley Steven M , Hammill Bradley G , Merritt James G , Zemon Doris N , Hernandez Adrian F , Jones W Schuyler
Published: April 2023

Background:

We aimed to understand the effects of aspirin dose on outcomes in patients with peripheral artery disease (PAD) as well as their participation in a pragmatic randomized controlled trial.

Methods:

In a subanalysis of the Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness (ADAPTABLE) study, we compared aspirin doses (81 vs 325 mg) among participants with PAD and study participation metrics in patients with and without PAD. The primary outcome composite was all-cause mortality, nonfatal myocardial infarction, and nonfatal stroke.

Results:

Among 14,662 participants enrolled in ADAPTABLE with PAD status available, 3493 (23.8%) had PAD. Participants with PAD were more likely to experience the primary composite (13.76% vs 5.31%, p < 0.001), all-cause mortality (7.55% vs 3.01%, p < 0.001), myocardial infarction (5.71% vs 2.09%, p < 0.001), stroke (2.45% vs 0.86%, p < 0.001), and major bleeding (1.19% vs 0.44%, p < 0.001). A higher aspirin dose did not reduce the primary outcome in patients with PAD (13.68% vs 13.84% in 81 mg and 325 mg groups; OR 1.05, 95% CI 0.88–1.25). Participants with PAD were less likely to enroll via email (33.0% vs 41.9%, p < 0.0001), less likely to choose internet follow-up (79.2% vs 89.5%, p < 0.0001), and were more likely to change their aspirin doses (39.7% vs 30.7%, p < 0.0001).

Conclusions:

ADAPTABLE participants with PAD did not benefit from a higher dose of aspirin and participated in the study differently from those without PAD. These results reinforce the need for additional PAD-specific research and suggest that different trial strategies may be needed for optimal engagement of patients with PAD. (ClinicalTrials.gov Identifier: NCT02697916)
Vexed in the city: Femme Failure in the World of Carrie Bradshaw and the “Long-Winded Lady”
Authors: O’Rourke Edward
Published: April 2023

Carrie Bradshaw, heroine of HBO’s Sex and the City, remains a talking point of pop culture. Tutued flâneuse, Bradshaw succeeds a long line of unconventional, feminist pathfinders, of whom Maeve Brennan’s Long-Winded Lady is arguably an early archetype. In her New Yorker dispatches, Brennan’s semi-autobiographical ‘dandette’ enacts a repudiation of the patriarchy by staking a claim to the public space of the city. This paper traces the resistant legacy of femme failure from Brennan to Bradshaw as single, non-reproductive women. Drawing on recent femme scholarship, it further explores the concept of paradoxical visibility in the lives of these fem(me)inine icons.
The Danish landscape of providing support for caregivers of people with potentially life-threatening disease: A cross-sectional study among representatives of health services in Danish municipalities and hospitals
Authors: Dieperink Karin B. , Møller Jens-Jakob K. , Mikkelsen Tina B. , Nissen Nina Konstantin , La Cour Karen , Rottmann Nina
Published: April 2023

Aims:

(a) To investigate support for caregivers of people diagnosed with stroke, cancer, chronic obstructive pulmonary disease (COPD), dementia, or heart disease provided across healthcare settings in Denmark; (b) to assess differences in caregiver support across diagnoses and settings.

Methods:

A cross-sectional nationwide survey among professionals representing healthcare settings at municipalities ( n = 479) and hospital wards and outpatient clinics ( n = 425). The survey assessed identification of caregivers and support initiatives.

Results:

The response rate was 81% for municipalities and 49% for hospitals. Identification of caregivers was frequent in dementia care (81% and 100%) and less frequent in COPD care (58% and 64%) in municipalities and hospitals, respectively. Caregiver support differed significantly across diagnoses within municipalities ( p = 0.009) and hospitals ( p < 0.001). Systematic identification of vulnerable caregivers was <25% for all diagnoses except dementia. The most common support initiatives involving caregivers were primarily aimed at the ill person and included guidance about the disease and consequences for everyday life and lifestyle changes. Caregivers were least involved in support initiatives addressing physical training, work retention, sexuality, or cohabitation.

Conclusions:

Disparities and significant differences across diagnoses exist in the identification of caregivers and the provision of support initiatives. Support initiatives involving caregivers primarily targeted patients. Future studies should investigate how caregivers’ needs can be met across different diagnoses and healthcare settings and investigate potential changes in caregivers’ needs during disease trajectories. In clinical practice, identification of vulnerable caregivers should be a major focus, and disease-specific clinical guidelines may be required to ensure sufficient support for caregivers.
A qualitative exploration of the experiences of young people and their parents regarding the impact of missing school to attend hospital-based orthodontic appointments
Authors: Oyeleye Teniola , Walker Roz , Cunningham Susan J
Published: April 2023

Objective:

To explore the experiences of young people and their parents regarding the impact on school performance due to time away from school for orthodontic appointments and to explore their views about a possible extension to the current service.

Design:

A qualitative study using semi-structured interviews.

Setting:

UK district hospitals.

Participants:

A total of 11 pairs of interviewees: young people undergoing fixed appliances and their parents.

Methods:

Semi-structured interviews were conducted with young people and their parents. The interviews were audio recorded and transcribed verbatim. A framework approach was used to analyse the data.

Results:

A thematic analysis of the data identified five main themes which were as follows: (1) expectations of the treatment process and appointments; (2) impact of school absences and treatment; (3) appointments; (4) implications for young people, parents and others; and (5) satisfaction with treatment. These themes were then further subdivided and analysed.

Conclusion:

Young people and their parents felt that attending appointments for orthodontic treatment had minimal impact on a young person’s school performance. However, some young people did engage in coping mechanisms in order to ensure this was the case. Young people and their parents advised they were satisfied with the process of the treatment despite the time missed at school/work. Some young people and their parents saw a real benefit to appointments that could be fitted into a ‘NHS seven-day’ service model, but this did not apply to all interviewees.
The socio-economic argument for the human right to internet access
Authors: Reglitz Merten
Published: April 2023

This paper argues that Internet access should be recognised as a human right because it has become practically indispensable for having adequate opportunities to realise our socio-economic human rights. This argument is significant for a philosophically informed public understanding of the Internet and because it provides the basis for creating new duties. For instance, accepting a human right to Internet access minimally requires guaranteeing access for everyone and protecting Internet access and use from certain objectionable interferences (e.g. surveillance, censorship, online abuse). Realising this right thus requires creating an Internet that is crucially different from the one we currently have. The argument thus has wide-ranging implications.
The education-world dilemma of Education’s autonomy: The case of K-12 engineering education
Authors: Yosef-Hassidim Doron
Published: April 2023

This paper addresses a dilemma of education’s autonomy: if an educational goal is to be universal, how do people’s current problems and concerns are supposed to be integrated or addressed in the educational work, and specifically in teaching the curriculum? The paper looks at this dilemma with a particular educational perspective and within a particular curricular context, namely, how Biesta’s (2022) ideas of grown-up-ness and a middle ground can be employed in K-12 engineering courses. The notion of relative autonomy in education is analyzed and rejected as a way to address the dilemma. Instead, expansive approaches to engineering are reviewed to analyze how their ethical frameworks offer insights about K-12 engineering education that support education’s autonomy. Following Biesta’s work and these frameworks, it is suggested to introduce resistance and raise issues of social power structures in K-12 engineering education, and to shift the attention about engineering from a future occupation in which one needs to be trained to a sphere of human interactions that invites and encourages students to demonstrate grown-up-ness. The paper offers creating situations that “shake” (but not break) the ground beneath the engineering aspirations of the students, and pulling students in and out of what we might call the engineering “zone”; between the world-destruction end of taking the engineering path towards engineering studies and career in any cost and whatever are the difficulties and consequences, and the self-destruction end of regarding engineering as something that is not for me after experiencing it in school. The educational work of the teacher is to push students toward (or encourage to stay in) the in-between area that involves doubts regarding the students’ “existential fitness” to demonstrate human subject-ness. The paper demonstrates the complexity in characterizing education’s relationships with specific social spheres and practices if education’s autonomy is to be maintained.
Perspectives and Attitudes of Dutch Healthcare Professionals Regarding the Integration of Complementary Medicine in Oncology
Authors: Schouten Aniek E.M. , Mentink Marit D.C. , Timmer-Bonte Johanna (Anja) N.H. , Noordman Janneke , van Dulmen Sandra
Published: April 2023

Introduction:

Almost half of all patients with cancer use complementary medicine (CM) alongside conventional cancer treatment. Further integration of CM into clinical practice could enhance communication and ensure improved coordination between complementary medicine and conventional care. This study assessed the perspectives of healthcare professionals on the current status of integration of CM in oncology, as well as their attitudes and beliefs toward CM.

Methods:

A convenience, volunteer sample of healthcare providers and healthcare managers working in oncology in the Netherlands were surveyed, using a self-reporting, anonymous, online questionnaire. The perspectives on the current status of integration and barriers to implementing complementary medicine were characterized in part 1, while part 2 assessed respondents’ attitudes and beliefs regarding CM.

Results:

A total of 209 people completed part 1 of the survey and 159 people completed the entire questionnaire. Two-thirds (68.4%) of the respondents indicated that their organization has implemented complementary medicine in oncology, or envisions implementation, while 49.3% stated they were missing something to implement CM in oncology. About 86.8% of the respondents (completely) agreed that complementary medicine is an important supplement to oncological treatment. Female respondents were more likely to express positive attitudes, as well as respondents whose institutions have implemented CM.

Conclusion:

The findings of this study indicate that attention is being paid to the integration of CM into oncology. Overall, the attitudes of respondents toward CM were positive. The main barriers for implementing CM activities were missing knowledge, experience, financial support, and support from management. To improve the ability of healthcare providers to guide patients in their use of complementary medicine, these issues should be delved into in future research.
Comparison of AngioJet Thrombectomy System Versus Suction Catheter with the Adjunct of Catheter-Directed Thrombolysis for Lower Extremity Deep Venous Thrombosis
Authors: Guo Hui , Gan Hai-run , Zhang Yong-yu , Wang Da-shuai , He Jia-nan , Zhao Ni , Huang Wei-le , Pang Peng-fei
Published: April 2023

Background

This study aims to investigate the value of the AngioJet thrombectomy system with adjunct of catheter-directed thrombolysis (CDT) in treating lower extremity deep venous thrombosis (LEDVT).

Methods

48 patients who were clinically confirmed LEDVT and treated by percutaneous mechanical thrombectomy (PMT) combined with CDT, were included in this retrospective study (AJ-CDT, n = 33; Suction-CDT, n = 15). Baseline characteristics, clinical outcomes and surveillance data were reviewed and analyzed.

Results

The overall clot reduction rate of AJ-CDT group was significantly higher than that of Suction-CDT group (77.86% vs 64.47%, P = .027). The CDT therapeutic time (5.75 ± 3.04 vs 7.67 ± 2.82 days, P = .045) and urokinase dosage (3.63 ± 2.16 vs 5.76 ± 2.12 million IU, P = .003) were lower in AJ-CDT group, respectively. There was statistical significance in the transient hemoglobinuria between 2 groups (72.73% vs 6.67%, P < .001). At postoperative 48 hours, the serum creatinine (Scr) value was higher in AJ-CDT group compared to Suction-CDT group statistically (78.56 ± 32.16 vs 60.21 ± 15.72 μmol/l, P = .049). However, the incidence of acute kidney injury (AKI) and uric acid (UA) concentration at postoperative 48 hours between these 2 groups were no statistical difference. There was no statistical significance in the Villalta score and post-thrombosis syndrome (PTS) incidence during postoperative follow-up.

Conclusions

AngioJet thrombectomy system is more effective for the treatment of LEDVT by providing a higher clot reduction rate with shorter thrombolytic time and lower thrombolytic drug dosage. However, the device-related potential risk of renal function injury should be taken appropriate precautions.
Antiracist Interventive Interviewing: Subverting Colonial Interventions with Public Sector Workers
Authors: Allen Willow Samara , Nath Nisha , Georges Trista
Published: April 2023

What does it mean to intervene in antiracist interviews with public sector workers? What do interventions look like in research seeking to name complicity in settler colonial violence and imagine otherwise relationships between non-Indigenous and Indigenous people? How might we methodologically define interventions and their pedagogical purpose(s)? In this paper, we share our experience of adopting a dual-pedagogical antiracist interventive research methodology in our qualitative research with public sector workers on settler colonial socialization. Building on antiracist interventive interviewing method, we map out our conceptualization of interventions as multidirectional and multiscalar. We narrate how we see interventions as dual pedagogical moments of disruption and possibility occurring at three scales, where we intervene to support our participants’ learning and they intervene to support ours. Our approach is illuminated through illustrations from our transcribed data of virtual interviews with 32 public sector workers in BC ( n = 23) and Alberta ( n = 9), and through our reflections on our research process. Our analysis demonstrates that interventions have three key effects. First, they are generatively disruptive in that they offer better access to understanding processes of settler colonial socialization. Second, interventions create junctures for antiracist and anticolonial learning. Third, interventions with participants open up opportunities to imagine otherwise beyond the strictures of settler colonialism, and orient towards anticolonial praxis rooted in recognition of Indigenous sovereignties. We conclude with a vocabulary of interventions meant to offer other qualitative researchers possibilities for how to intervene to better access and disrupt sites of deep colonizing.
The case-control study on relationship between the serum concentration of IL-7 and the pathogenesis of psoriasis: ampere systematic review and meta-Analysis
Authors: Liu Jiandong , Zeng Linxi , Huang Xin , Liu Lu , Guo Nana , Zhang Jinfang , Zhang Guoqiang
Published: April 2023

Objective

To explore the relationship between the serum concentration of IL-17 and the pathogenesis of psoriasis.

Methods

ampere database was established through literature search, and meta-analysis was used to evaluate the effect indicator of the included literatures.

Results

5 articles were included in the study, and the quality evaluation score was 6–7 points by the Newcastle-Ottawa Scale (NOS) criteria. There was heterogeneity in the standardized mean difference (SMD) between the two groups (I2 = 98.63%). The random effect model analysis showed that the combined SMD = 2.11, 95%CI (0.79, 3.43), the effect size between studies was statistically significant (z = 3.13, p = 0.00).

Conclusion

There was a statistical difference in serum IL-17 concentration between the case group and the control group. The serum concentration of IL-17 in the case group was higher than that in the control group.
Research Responsibility Agreement: a tool to support ethical research
Authors: Murdock Melanie , Erickson Stephanie
Published: April 2023

When engaging in community-based research, it is important to consider ethical research practices throughout the project. While current research practices require many investigators to obtain approval from an ethics review board before starting a project, more is required to ensure that ethical principles are applied once the investigations begin and after the investigations are complete. In response to this concern, as expressed by workers at a feminist non-profit during a community placement, we developed a tool to foster both greater ethical and feminist research practice in community-based research. Using feminist theories, methodologies, and concepts such as epistemic justice, epistemic trust, and coauthorship, a tool was developed to support researchers and other collaborators in building relationships of reciprocity. This tool, called the Research Responsibility Agreement (RRA) invites all members of a research project to explicitly reflect on their role in the research, their relationships with other collaborators, their responsibility to contributing meaningfully in the project, and their plans to remain accountable to one another. In doing so, the RRA adds to existing tools that support ethical research by sharing explicit reflections from all collaborators on how to prevent harm and by asking them to reflect on ethical practices beyond the initial stages of the project. The RRA also encourages greater engagement from researchers and collaborators toward building meaningful relationships with each other, and with participants, to work together in advancing social change. As a practical tool that promotes reflection, that builds relationships, and that holds all parties accountable to ethical and feminist research practices, the RRA has the potential to generate impactful change in community-based research projects and beyond. While the RRA is tailored to community-based research, it can be applied widely to any research project and has the potential to revolutionize how research relationships are built across disciplines.
Clinical and electrophysiological characteristics of peripheral neuropathy in autoimmune glial fibrillary acidic protein astrocytopathy: an observational study and literature review
Authors: Deng Bo , Wang Jingguo , Qiu Yue , Liu Xiaoni , Jin Lei , Zhu Dongqing , Chen Xiangjun
Published: April 2023

Background:

The phenotype of peripheral neuropathy (PN) associated with glial fibrillary acidic protein-immunoglobulin G (GFAP-IgG) has not been well described.

Objectives:

The aim of this study was to report the frequency, clinical, and electrophysiological characteristics of PN in GFAP-IgG-positive patients.

Design:

This study is a single-center retrospective observational study.

Data Sources and methods:

GFAP-IgG-positive patients with PN were retrospectively identified from the Huashan Hospital Autoimmune Encephalitis Cohort between 2017 and 2021. Eight patients who presented with PN from other published studies were also included in the analysis. The clinical and electrophysiological characteristics of GFAP-IgG-related PN were described.

Results:

A total of 21 (31%) patients (7 females, 14 males; Mage: 42 ± 16 years) from a cohort of 68 GFAP-IgG-positive patients presented with PN. Twenty of 21 patients had symmetrical weakness. Sensory and autonomic symptoms were present in 16 and 15 patients, respectively. Lower extremities were the most frequently involved regions for both motor (20/21) and sensory (15/21) symptoms. Moreover, 13 patients (4 females, 9 males; Mage: 43 ± 13 years) had electrodiagnostic study data, and 12 of 13 patients had abnormal findings. Regarding clinical features, motor nerve fibers were predominantly involved (12/13), and symmetric lower extremities (12/13) were the most commonly affected regions. Axonal neuropathy is the typical underlying pathophysiologic process of PN. All 21 patients responded to immunotherapy. However, four patients with tetraplegia had poor outcomes, and PN was the major determinant of their long-term disability. Most cases (6/8) from the literature presented with similar clinical and electrophysiological features to those from our cohort.

Conclusion:

Peripheral nerves could be involved in autoimmune GFAP astrocytopathy. Predominant motor axonal neuropathy mainly involving the lower extremities is the most common PN phenotype in this disorder. GFAP-IgG-related PN is responsive to immunotherapy.

Registration:

Chinese Clinical Trial Registry: ChiCTR2000029115 ( http://www.chictr.org ).
Pediatric diffuse hemispheric glioma H3 G34-mutant with gains of the BRAF locus: An illustrative case
Authors: Marlow Christine , Cuoco Joshua A , Hoggarth Austin R , Stump Michael S , Apfel Lisa S , Rogers Cara M
Published: April 2023

Diffuse hemispheric glioma, H3 G34-mutant, is a recently recognized distinct high-grade glioma with a dismal prognosis. In addition to the H3 G34 missense mutation, numerous genetic events have been identified in these malignant tumors, including ATRX, TP53, and, rarely, BRAF genes. There are only a few reports to date that have identified BRAF mutations in diffuse hemispheric glioma, H3 G34-mutant. Moreover, to our knowledge, gains of the BRAF locus have yet to be described. Here, we present a case of an 11-year-old male with a diffuse hemispheric glioma, H3 G34-mutant, found to have novel gains of the BRAF locus. Furthermore, we emphasize the current genetic landscape of diffuse hemispheric glioma, H3 G34-mutant, and implications of an aberrant BRAF signaling pathway.
Finance Kaart: A fintech for the “credit invisibles” in India
Authors: Anurag Priyatam
Published: April 2023

In this case, we describe the journey of Finance Kaart, a fintech start-up with a vision to serve India’s financially excluded customer segments. We explore the strategic options available to the start-up and its founder’s rationale for developing an online marketplace business model focused on Micro, Small and Medium Enterprise customers in small towns of India. The case further explores how India’s fintech ecosystem enabled frugal innovation by start-ups such as Finance Kaart. In a supportive ecosystem, Finance Kaart followed a partnership-driven approach but needed to address investor concerns regarding its “over-dependence on the partners” that arguably limited its profit potential. We conclude by discussing how Finance Kaart planned to overcome the challenges to its growth strategy by transforming it into a Neo-bank.
How Family and a Migrant Background Influence Family Entrepreneurship: Findings from a Systematic Literature Review
Authors: Hadri Valdet , Dvouletý Ondřej , Bögenhold Dieter , Sawy Alina
Published: April 2023

This article aimed to survey the literature on the authenticity and influence of family and migration in the context of family entrepreneurship with the goal of highlighting thematic trends within the existing literature, mapping and outlining existing knowledge in the field, and recommending future research directions. The method used in this study is a systematic literature review approach consisting of five stages. Out of the 320 articles indexed in Web of Science’s Core Collection in 2014–2020, 64 were selected and studied extensively. Additionally, NVivo software Windows (Student License) software—Windows (12-month Student License) was used to examine the most frequently researched thematic areas by analysing the occurrence of the keywords in the articles concerned. The study provides an overview of six major research streams on the influence of family and migration background within the context of family entrepreneurship: (a) the influence of family on the entrepreneurial orientation of family firms, (b) the socio-cultural influence of family in family entrepreneurship, (c) family influence in corporate family enterprises, (d) family influence in family-governed firms, (e) the influence of gender within family entrepreneurship and (f) the influence of the family in the context of migrant-run family entrepreneurship. However, the survey was only conducted in the Web of Science database and only focused on work written in English, limiting the range of studies that were analysed. Thus, multilingual teams could expand the research by studying non-English texts and identifying studies in other scholarly databases.
Impact of COVID-19 on Market Sentiment and Abnormal Returns in India: A Comparative Analysis of Two Waves
Authors: Mundi Hardeep Singh , Yadav Yamini
Published: April 2023

This study examines the impact of COVID-19 on market sentiment and the stock market’s reaction at different investors’ time horizons in India. We applied wavelet coherence analysis and event study methodology during waves 1 and 2 of COVID-19 on NIFTY 50 firms. The results of this study report that market-related implicit sentiment proxies depicting the market’s bullish (bearish) sentiment negatively (positively) correlate with COVID-19 during the first wave of the pandemic in the short-term to medium-term (until 16 days). Using the event study method to compute abnormal stock returns during waves 1 and 2 of COVID-19, we found statistically significant negative abnormal returns during wave 1 only. Our findings extend the literature that examines the market reaction to COVID-19. The results generally hold for various robustness checks.
Creating Normative Growth Curves for Pediatric Upper Airway Volume
Authors: Prescher Hannes , Jiang David , Siddiqui Sahar , Giurcanu Mihai , Reid Russell R. , Collins John M.
Published: April 2023

Background:

The objective of this study was to create normative growth curves for pediatric upper airway volume using 3D computed tomography with emphasis on the neonatal age group.

Methods:

We completed a single-institution, retrospective review of all patients with available CT scans between the ages of 0 and 60 months. Patients were excluded if they exhibited any maxillofacial dysmorphism or upper airway pathology or if scans showed the presence of airway appliances or tubes. 3D volumetric upper airway analysis was performed and 2D cephalometric measurements and growth parameters including height, weight and age were recorded for all patients. Linear regression analysis was used to develop a prediction model for airway volume in terms of age adjusting for cephalometric and growth parameters stratified by sex and the resulting model was used to create separate percentile curves for each sex group.

Results:

The growth curves were created based on CT scans from 217 healthy patients. Mean airway volume was significantly larger in males than females (3.23 ± 1.98 mm3 vs 2.61 ± 1.64 mm3, p = 0.017).

Conclusions:

Normative growth curves for neonatal and pediatric upper airway volume are a useful tool for tracking changes in airway volume in the growing infant.
‘Our community building and belonging’: A student and staff co-creation project
Authors: Shakir Syra , Siddiquee Asiya
Published: April 2023

This article presents an evidence-based case study of a co-creation research project aimed to build and improve a sense of belonging and community through co-created activities, events, and campaigns. Various activities brought together both students and staff across a post-92 university in the North of England. The co-created project gathered empirical data to explore how belonging and community were experienced by students, evaluated the impact of the co-created events and campaigns for students, and highlighted key areas for the university to further develop. These included recommendations for how the university supports students to feel a sense of belonging, the efficacy of its Race Equality Charter action plan addressing differential outcomes, the learning and teaching approach around using co-creation, embedding equity and social justice within both curriculum and student support services, improved communication systems with students, and ensuring the concept of belonging is at the forefront of student experience. The article concludes by highlighting the intrinsic connection to retention, progression, and success for students with feeling a sense belonging in higher education and describes how co-creation can be used for social justice and equity activism to bring about positive changes to benefit a whole university community.