bluuebunny/crossref_metadata_2025 huggingface dataset:
Chromosome-level genome assembly and characterization of Sophora japonica
Authors: Lei Weixiao , Wang Zefu , Cao Man , Zhu Hui , Wang Min , Zou Yi , Han Yunchun , Wang Dandan , Zheng Zeyu , Li Ying , Liu Bingbing , Ru Dafu
Published: January 2024

Sophora japonica is a medium-size deciduous tree belonging to
Leguminosae family and famous for its high ecological, economic, and
medicinal value. Here, we reveal a draft genome of S. japonica,
which was approximately 511.49 Mb long (contig N50 size of 16.15 Mb)
based on Illumina, Nanopore and Hi-C data. We reliably assembled 110
contigs into 14 chromosomes, representing 91.62% of the total genome,
with an improved N50 size of 31.32 Mb based on Hi-C data. Further
investigation identified 271.76 Mb (53.13%) of repetitive sequences and
31,000 protein-coding genes, of which 30,721 (99.1%) were functionally
annotated. Phylogenetic analysis indicates that S. japonica
separated from Arabidopsis thaliana and Glycine max about
107.53 and 61.24 million years ago, respectively. We detected evidence
of species-specific and common-legume WGD events in S. japonica.
We further found that multiple TF families (e.g., BBX and PAL) have
expanded in S. japonica, which might have led to its enhanced
tolerance to abiotic stress. In addition, S. japonica harbors
more genes involved in the lignin and cellulose biosynthesis pathways
than the other two species. Finally, population genomic analyses
revealed no obvious differentiation among geographical groups and the
effective population size continuously declined since 2 Ma. Our genomic
data provide a powerful comparative framework to study the adaptation,
evolution and active ingredients biosynthesis in S. japonica.
More importantly, our high-quality S. japonica genome is
important for elucidating the biosynthesis of its main bioactive
components, and improving its production and/or processing.
Prescription Writing - Are We Training our Students Adequately?
Authors: Hashmi Arif , Hashmi Rupinder Kaur , Alghamdi Talal
Published: January 2024

Teaching of Clinical Pharmacology has taken a backseat in most medical
schools worldwide, especially with the introduction of newer methods of
learning. Appropriate prescription writing skills depend on a large
measure on the understanding of Clinical Pharmacology and therapeutics.
The necessity of acquiring appropriate prescription writing skills, at
the same time coupled with a reduction in time allotted to the teaching
of Clinical Pharmacology poses unique problems. Through the introduction
of a special module geared towards teaching prescribing skills to
medical students, we have made an effort to mitigate the effects of
reduction in time allotted to Clinical Pharmacology teaching. Our
experience in this regard has been positive and we have found the module
has served its purpose well.
Generalized inequalities of the Mercer type for strongly convex functions
Authors: Khan Muhammad Adil , Alam Fayaz , Nwaeze Eze , Iqbal Sajid
Published: January 2024

A generalization of the Mercer type inequality, for strongly convex
functions with modulus $c>0$, is hereby established. Let
$\mathfrak{h}:[\delta,\zeta]
\rightarrow \mathbb{R}$ be a strongly
convex function on the interval
$[\delta,\zeta]
\subset \mathbb{R}$. Let
${\bf a}=(a_1,….,a_s)$,
${\bf b}=(b_1,….,b_s)$ and
${\bf p}=(p_1,….,p_s)$, where $a_k, b_k
\in [\delta,\zeta],
p_k >0$ for each $k=\overline{1,s}$.
If ${\bf
n}\in{\mathbb{R}}^s$,
$\langle {\bf a}-{\bf
b}, {\bf n}\rangle=0$ and under some
separability assumptions, then we prove that
$$\sum_{l=1}^s
p_l\mathfrak{h}(b_{l}) \leq
\sum_{l=1}^s
p_l\mathfrak{h}(a_l)-c\sum_{l=1}^sp_l(a_l-b_{l})^2.$$
Using the above result, we derive loads of inequalities for similarly
separable vectors. We further applied our results to different types of
tuples. Our results extend, complement and generalize known results in
the literature.
Sign-changing solutions to a fractional Choquard system with strongly indefinite structure
Authors: Chen Jianqing , Zhang Qian
Published: January 2024

In this paper, we study the following coupled fractional Choquard system
$$\left\{\aligned&(-\Delta)^s
u+V(x)u=\frac{2q}{p+q}\bigl(I_\alpha\ast|u|^p\bigr)|v|^{q-2}v,\\
&(-\Delta)^s
v+V(x)v=\frac{2p}{p+q}\bigl(I_\alpha\ast|v|^q\bigr)|u|^{p-2}u,\\
&\ u(x)\to0\
\ \hbox{and}\
\ v(x)\to0\
\ \hbox{as}\
|x|\to\infty,\endaligned\right.
$$ where $02s,\frac{N+\alpha}{N}
Global Practical Output Tracking for a class of Uncertain Inherently Time-Varying Delay Nonlinear Systems by output feedback
Authors: Alimhan Keylan , Mamyrbayev Orken , Adamov Abilmazhin , Alisheva Sandugash , Oralbekova Dina
Published: January 2024

This article addresses the problem of global practical output tracking
by output feedback for a class of uncertain inherently time-varying
delay nonlinear systems. Firstly, a homogeneous output-feedback
controller is designed for the nominal uncertain inherently system by
virtue of adding a power integrator technique. Then, with the help of an
appropriate Lyapunov-Krasovskii functional and reduced-order observer,
by using homogeneous domination approach and the adding a power
integrator method, an output feedback controller is successfully
developed to guarantee all the states of the closed-loop system remain
to be bounded and simultaneous make the tracking error arbitrarily
small. The simulation results of an example verify the proposed approach
Endovascular Treatment for Early and Delayed Life-Threatening Hemorrhage Following Tracheostomy: Our Experience in Four Patients
Authors: Zavdy Ofir , Grinblat Golda , Hebron Dan , Shochat Isaac , Maayan Dor , Watad Waseem , Dudkiewicz Mickey , Braverman Itzhak
Published: January 2024

INTRODUCTION Post tracheostomy hemorrhage is a potentially
life-threatening complication that occurs in approximately 1% of cases
and requires immediate intervention. Iatrogenic vascular injury to the
jugular and carotid vessels and branches of the neck during surgery is
usually the cause for major bleedings during the immediate postoperative
period, lasting up to 3 days. Delayed bleeding is usually the result of
a tracheal erosion by a major artery, leading to pseudoaneurysms or
fistulae. In most cases, the innominate artery is involved, resulting in
trachea-innominate artery fistula (TIAF), with mortality rates reaching
100%. In some cases, sentinel bleeding, hemoptysis, or pulsation around
the cannula may precede. In the past, the only treatment options for
acute and delayed bleeding were open surgery to repair, ligate or resect
the damaged vessels. Once the bleeding is controlled, repair of the
tracheal fistula is indicated. Reported success rates following surgical
repairs are low, with high morbidity and mortality of more than 75%. In
recent years, an endovascular approach is replacing the need for
surgery, with higher survival rates of over 70% and fewer
complications. Objectives To describe our experience with endovascular
treatments for immediate and delayed post-tracheostomy hemorrhage.
Changes in the climate suitability and growth rates of trees in eastern North America
Authors: Bernal-Escobar Manuel , Zuleta Daniel , Feeley Kenneth
Published: January 2024

According to the “fitness-suitability” hypothesis, ongoing changes in
climate are expected to affect species’ fitness and habitat suitability.
In trees, differences in fitness may manifest as changes in growth
rates, which alters carbon uptake. Using tree-ring data, we calculated
annual growth rates for 15,866 trees representing 37 species from 558
populations throughout eastern North America. We used species
distribution models to estimate each population’s climatic suitability
from 1900-2010. Growth rates and relative climatic suitabilities were
analyzed using linear mixed-effects models. There were no significant
relationships between growth rates and climate suitability across space
or time. However, growth rates have decreased significantly through time
independent of changes in climate suitability, especially in
gymnosperms. These results suggest that unidentified factors may slow
tree growth and outweigh potential benefits of climate change and
increasing [CO2]. Consequently, we should not count on growth of
eastern North American trees to help offset anthropogenic carbon
emissions.
Pulmonary Aspergillosis After Covid-19, A Case Report
Authors: Hazer : Seray , Göktepe Gülşen , Acar Leyla , Gülhan Selim Şakir Erkmen
Published: January 2024

This study presents a 57-year-old male patient with COVID-19 who had had
no lung disease before COVID-19 pneumonia. However, after COVID-19
pneumonia with sequels and treatments that include corticosteroids and
IL-6 receptor antagonists, an invasive pulmonary aspergillus (IPA)
cavity occurred immediately.
Spectrum and clinical characteristics relevance of gene mutations in Chinese pediatric acute lymphoblastic leukemia
Authors: Shen Diying , Liu Lixia , Xu Xiaojun , Song Hua , Zhang Jing-Ying , Xu Weiqun , Zhao Fenying , Liang Juan , Liao Chan , Wang Yan , Xia Tian , Wang Chengcheng , Lou Fen , Cao Shanbo , Qin Jiayue , Tang Yongmin
Published: January 2024

Purpose：the 5-year survival rate of children with acute lymphoblastic
leukemia (ALL) is 85–90%, with a 10–15% rate of treatment failure.
Thus, an in-depth understanding of the biological characteristics of
these patients is essential. Approximately 30% of pediatric B cell
precursor (BCP)-ALL patients remain uncharacterized by the genetic
analyses at the time of diagnosis. The present study aimed to
characterize the spectrum and clinical relevance of recurrent driver
gene mutations in a large single-center cohort of pediatric ALL.
Methods：we identified the spectrum of somatic mutations in 219
pediatric ALL by next-generation sequencing and analyzed the correlation
with the clinical data. Results: a total of 381 gene mutations,
including SNVS and InDels, were identified in 66 different genes in
152/219 patients. Conclusion: this study depicted the specific genomic
landscape of Chinese pediatric ALL and revealed the relevance between
mutational characteristics and clinical features of Chinese pediatric
ALL.
Genetic characterization of a novel bovine Rotavirus A G37P[52] closely related to human strains
Authors: Mor Sunil , Singh Vikash , Neira Victor , Brito B.P. , Ariyama Naomi , Sturos Matt
Published: January 2024

Bovine Rotavirus A (boRVA) strains are a major causative agent of
diarrhea in calves. It inflicts important economic losses to the beef
and dairy industry. Importantly, this virus has a zoonotic relevance due
to its ability to reassort with human rotaviruses. In this study, we
describe a novel boRVA associated with diarrhea in calves and closely
related with human rotavirus strains based on whole genome
characterization.
Outcomes after transvenous defibrillator implantation in cardiac sarcoidosis: a systematic review
Authors: Taha Ahmed , Assaf Omar , Champsi Asgher , Roy Ashwin , Nadarajah Ramesh , A Peysh Patel
Published: January 2024

Introduction Sarcoidosis is a systemic inflammatory disorder
associated with ventricular arrhythmias (VAs) and sudden death in the
context of cardiac involvement. Established guidelines advocate
implantable cardioverter-defibrillator (ICD) implantation in specific
subcohorts, but there is a paucity of data on outcomes. Methods
and Results We conducted a systematic review of published literature to
assess outcomes in patients with cardiac sarcoidosis (CS) treated with
ICD. Observational studies of patients with definite or probable CS and
ICD implantation were identified from multiple databases from inception
to 21 May 2021. Outcomes of interest included
appropriate and inappropriate ICD therapies in addition to all-cause
mortality. Study quality was assessed individually using the Newcastle
Ottawa Scale (NOS). Eight studies were identified comprising 530
patients, with follow-up period of 24 to 66 months (weighted average 40
months). Mean age was 53.9 years with ejection fraction of 41.3%.
Overall incidence of appropriate therapy, reported in all studies, was
39% during follow-up. Left ventricular systolic dysfunction (LVSD) with
ejection fraction < 40% was a predictor of appropriate
therapy in the majority of studies, as were sustained VAs during
electrophysiological testing (EP) in one study. Inappropriate therapy
was documented in six studies and primarily driven by atrial
arrhythmias. All-cause mortality was reported in six studies, with
incidence of 6.0% over a median follow-up period of 42 months. Only
three studies achieved good quality in the comparability domain of NOS.
Conclusions Appropriate ICD therapy in patients with CS is
commonly associated with LVSD, which may act as a surrogate for scar
burden. The utility of EP testing in this setting remains unclear.
Using NOACS in Obese Patients: Just One More Thing To Consider With Anticoagulation?
Authors: Duncan Aaron , Lynch Olwyn
Published: January 2024

Atrial Fibrillation (AF) poses a significant burden to patients as well
as the healthcare system. It can be a complex diagnosis and requires a
holistic approach to treatment. Every patient with AF should be
evaluated for the need for anticoagulation therapy to prevent systemic
embolization. In those that require long-term anticoagulation, a novel
oral anticoagulation agent (NOAC) has become the drug of choice. In
recent years there have been huge developments in the field of
anticoagulation in AF with the presence of the various NOACs on the
market. However, there remains uncertainty around prescribing in obese
patients.
The Key Timing of Pharyngeal Reflux in Patients with Laryngopharyngeal Reflux
Authors: Kang Jeong Wook , Lee Young Chan , Ko Seong-Gyu , Eun Young Gyu
Published: January 2024

Objectives: To analyze the incidence of pharyngeal reflux in
laryngopharyngeal reflux patients over a 24-hour period and find out the
key timing of pharyngeal reflux. Design: Retrospective descriptive
analysis Setting: Single institution. Participants: Sixty-nine patients
with LPR and twenty-six normal controls Methods: We reviewed 69 patients
who visited our clinic with LPR-related symptoms and were proven to have
pharyngeal reflux via 24‐hour multichannel intraluminal impedance‐pH
(24hr MII‐pH) monitoring. Quantitative analysis was conducted for the
LPR profiles, such as the acidity of reflux, nighttime reflux, and
positional reflux. The time series of pharyngeal reflux episodes and
mealtimes were analyzed over a 24-hour period. Also, we recruited 26
normal controls. We compared the timing of pharyngeal reflux between LPR
patients and asymptomatic controls. Results: The quantitative analysis
revealed that pharyngeal reflux occurred 4.88 ± 4.59 times over 24
hours. Weakly acidic pharyngeal reflux was more abundant than acidic or
weakly alkaline reflux. Pharyngeal reflux occurred mainly during daytime
in the upright position. The most frequent timing of pharyngeal reflux
episodes was within 2 hours after meals. Additionally, there was no
significant difference of the timing of post-prandial reflux between LPR
patients and asymptomatic controls. Conclusion: The key timing of
pharyngeal reflux in patients with LPR was post-prandial 2 hours.
Artificial Intelligence: A Driving Force in advancing Patient Centricity
Authors: Aqeel Ubada , Urooj Mohd , Gera Shikha
Published: January 2024

One striking change that has occurred in what fundamentally drives
businesses today is the journey towards a ‘customer focused’ approach.
The healthcare industry has followed the same suit. Today’s patients or
beneficiaries expect the liberty of choice and the more personal or
individualistic these choices become, the better. In the current digital
age, patients are more informative and educated than ever. They know
their rights and are voicing about their concerns at the global
platforms. Healthcare Industry has no option but to meet the demands and
needs of the patients. Therefore, the current healthcare landscape is
undergoing essential modifications, attributed to the pressure created
to meet patient centered goals. With the advent of advanced technologies
and globalization, healthcare ecosystem is trying its best to meet their
demand at global level, where Artificial Intelligence (AI) is playing
the central role. The wave of AI has been increasing in the industry day
by day. The current article articulates about how AI and data science
are transforming life sciences and explains how this sector is deploying
these tools to meet patient centricity.
Comment on: Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults
Authors: Guo Li , Sun Yixue , Li Junfeng , Cong Yanlong , Zhao Jinghui
Published: January 2024

Recently, Spencer et al. published their interesting article
in Influenza and Other Respiratory Viruses providing evidence that there
is no impact of diabetes status on immunogenicity of trivalent
inactivated influenza vaccine in older adults. Although we agree with
the conclusion, we suggest that the transportation condition of
the serum samples should be added in the description of serological
surveys of influenza in the future. Stability of specific influenza
antibodies in sera samples stored in differing conditions should be
considered.
How to improve the post-graduate training of general practitioners in performing joint injection? Analysis of training courses and literature review
Authors: Vrignaud Arthur , Dernis Emmanuelle
Published: January 2024

Introduction: While several studies have shown the usefulness and
effectiveness of articular and abarticular corticosteroid injections
performed by general practitioners, the main limitation that has been
identified in expanding the use of these acts in everyday practice lies
in a lack of training. Thus, this study aimed to determine the best
settings for training courses concerning this subject. Methods: Our
study was composed of two parts: the first one consisted in a survey
concerning the improvements induced by training courses in the context
of continuing medical education on the participants’ skills and degree
of confidence, the second part was a review of the published literature
about this topic. Results: As expected, every training program analysed
through our survey generated improvements in the participants’
confidence in performing articular or abarticular injections.
Furthermore, these findings are reflected in an increase in the
proportion of such skills that the trainees complete by themselves.
These results were reinforced by similar findings raised by the
literature review. Moreover, it highlighted that hands-on training
courses seemed to be the most efficient and that the use of synthetic
models appeared to be a suitable alternative to human bodies or corpses,
surrounded by less ethical and logistic concerns. Conclusions: This
study supports the expansion of training courses for general
practitioners on articular and abarticular injections. It also suggests
that they should be based on a hands-on training design, possibly with
the use of manikins.
Parameter Estimation in Mass Balance Model applied in Fixed Bed Adsorption
Authors: Tavares Rhaisa , Dias Camila , Moura Carlos , Rodrigues Emerson , Viegas Bruno , Macedo Emanuel , ESTUMANO Diego
Published: January 2024

Maintaining potable water resources is a challenge that humanity cannot
ignore, given the growing increase in potential contaminants of
different classes. In the scenario of viable alternatives to the
remediation of this environmental setback, adsorption stands out for its
effectiveness, relative operational simplicity, and low cost. The use of
models in a simulated environment that represents the adsorptive
dynamics in a fixed bed column is presented to anticipate viable
scenarios and execution conditions before elaborating a full-scale
project. Analytical models are often used due to their simplicity of
application. However, their parameters remain limited to the specific
experimental curve used in their adjustment. In this sense, this work
adopts the mechanistic approach to using a model capable of providing
more detailed information about an adsorptive bed, such as axial
dispersion and mass transfer in the solid phase. We carried out the
verifications presented here from the perspective of Bayesian inference.
It allows the use of all previous knowledge of the phenomenon and
experimental measurements and their associated uncertainties. The mean
and standard deviation of the prior probability distribution of the
parameters were varied. We adopted the Monte Carlo method via Markov
Chains (MCMC) to obtain the estimates and implemented them according to
the Metropolis-Hastings algorithm. Estimates showed that information
obtained at bed outlet could predict breakthrough curves at other points
in the column where measurements are not available.
Complementary Theory of Evolutionary Genetics
Authors: Huang Xiaoqiu
Published: January 2024

This theory seeks to define species and to explore evolutionary forces
and genetic elements in speciation and species maintenance. The theory
explains how speciation and species maintenance are caused by natural
selection acting on non-Mendelian and Mendelian variation, respectively.
The emergence and maintenance of species as groups of populations are
balanced by evolutionary forces including complementary mechanisms of
gene flow within and between populations at population-specific rates:
sexual and asexual reproduction, recombining and nonrecombining genome
regions, vertical and horizontal DNA transfer, and transposon
proliferation and control. While recombining genome regions carry
conserved genes and are subjected to meiotic recombination,
nonrecombining genome regions carry accessory genes and are not
subjected to such structural restrain. Sexual reproduction, vertical DNA
transfer, recombining genome regions and transposon control keep species
in existence by maintaining recombining chromosome number and structure,
while asexual reproduction, horizontal DNA transfer, nonrecombining
genome regions and transposon proliferation help species emerge by
promoting reproductive isolation and changes in chromosome number and
structure. The theory is based on the analysis of the genome sequences
of isolates in the Fusarium oxysporum complex. The rate of horizontal
supernumerary chromosome transfer in this complex was estimated to be
0.1 per genome per year.
Improved Analytical Equation for Calculating Nickel-based Alloys Density
Authors: Milder Oleg , TARASOV Dmitry , Tiagunov Andrei
Published: January 2024

The density of metallic materials, along with strength and
corrosion-resistance, is one of the main physical characteristics. This
property is critical for nickel alloys, which are widely used in space
and aeronautics, where it is extremely important to minimize the mass of
each part. When developing new types of the alloys, it is essential to
have a reliable and accurate method for estimating density.
Unfortunately, no unified method for calculating the density has yet
been proposed, except several regression models that give more or less
accurate results. In this paper, we analyze and critically evaluate the
available approaches, and provide a group of advanced analytical
equations that accurately calculate the density of a nickel alloy based
on its chemical composition. The method takes into account the spatial
fcc structure of the alloys, the molar mass and molar volume of the
alloying elements, as well as, the behavior of light ligands. We verify
the accuracy of the equation based on real density and chemistry data
for 69 nickel alloys. Using all equations, we calculate the density and
compare the calculated data with real values. Comparison of the results
shows that the proposed method provides the best accuracy of all those
considered. The RMSE between the calculated values and the real ones is
about 0.07. The error of the regression methods is 0.5 at best. Thus,
the proposed approach increases the accuracy of calculating the density
of nickel alloys by about an order of magnitude, while significantly
simplifying it.
Evaluation the Quality of the Surgical Team in Performing Patient Safety Standards in Iranian Hospitals
Authors: Keshvari Sahar , Rarani Saeid Amini , shafie zahra , Mojdeh Soheila
Published: January 2024

Objectives: patient safety in the operating room is very important. The
aim of this study was evaluation the quality of the surgical team in
performing patient safety standards in Iranian hospitals. Methods: This
study was a descriptive cross-sectional study. The study population
consisted of 180 surgical cases in the operating room of selected
centers affiliated to Isfahan University of Medical Sciences. Data
collection tools include a checklist (including demographic
characteristics of patients and 134 items in 4 dimensions of standards
of anesthesia care before, during and after surgery, observance of
essential points in safe surgery, observance of the relationship between
the surgical team and the standard of patient movement and position
during Surgery). Software SPSS 16 was used to analyze the information.
Results: Respectively, the highest mean score to observe the standards
of anesthesia care, before, during and after surgery with the highest
score (70.7 ± 10.5), then observing the essential points in safe surgery
(65.4 ±19.3), Observing the relationship between the surgical team (57.5
± 18.8) and the standard of patient movement and position during surgery
(25.7 ± 7.9) were in the next ranks. In examining the relationship
between demographic characteristics and patient safety, patients’ gender
and education did not have a significant effect on the performance of
the surgical team (p>0.05), but with increasing age and
weight, the performance of the surgical team in observing safety
standards has increased significantly (p<0.05). Conclusion:
According to the results of this study, all members of the surgical team
should be more aware of safe surgery and more training programs should
be developed for members of the surgical team on compliance with the
standards of patient safety in operating room.
Does leaf gas exchange correlate with petiole xylem structural traits in Ulmus leavis seedlings under optimal and drought stress conditions?
Authors: Gebauer Roman , Urban Josef , Volařík Daniel , Matoušková Marie , Vitásek Roman , Houšková Kateřina , Hurt Václav , Pantová Petra , Polívková Terezie , Plichta Roman
Published: January 2024

Despite the great diversity in leaf structural and physiological traits,
leaf structural traits appear to be coordinated with physiological
function. It was observed that the petiole xylem structure is an
important predictor of leaf gas exchange capacity, yet only a few
studies have dealt directly with the question of how petiole xylem
structure relates to leaf gas exchange. An understanding of the amount
of variation that exists within a single species is also limited. In
this study, we investigated the intraspecies coordination of leaf gas
exchange and petiole xylem traits in two-year old seedlings of
Ulmus leavis Pall. during optimal and drought conditions. It was
found that all studied petiole xylem traits of the elm seedlings were
positively correlated with each other. This shows that the development
of petiole xylem structure is internally well-coordinated. Nevertheless,
the lower correlation coefficients between some petiole xylem traits
indicate that the coordination is also individually driven. Drought
stress reduced all studied leaf gas exchange traits and significantly
increased intraspecies variation. Drought stress also shifted the
relationships between physiological traits. Moreover, there were more
structure-function relationships under stress conditions. This indicates
the importance of petiole xylem structure in dictating the water loss
during drought stress. It could partly explain the inconsistencies
between leaf structure-function relationships studied under optimal
conditions. Although several structural-functional traits were related,
the range correlation coefficients indicate that the internal
coordination between structural-functional traits differs substantially
between individual elm seedlings. These findings are very important in
the context of expected climatic change, as some degree of phenotypic
plasticity in structure-function relationships could ensure the survival
of some individuals under different environmental conditions.
Η2 and Η∞ Filtering for Discrete-Time Switched Affine Systems
Authors: Fu Zhenting , Xu Xiaozeng , Yang Xinyue , Zhang Hongbin , Zheng Qunxian
Published: January 2024

This paper focuses on solving Η and Η
filtering problems for discrete-time switched affine systems. A newly
proposed Lyapunov stability analysis method in which considered that the
system will converge to limit cycles instead of equilibrium points or
regions was used in solving such problems for the first time. In the
stability analysis of a discrete-time affine filtering error system, an
observer-based filter and its corresponding switching function can be
obtained by solving the linear matrix inequalities. Furthermore, it is
proved that the Η and Η guaranteed
cost is upper bounded, the upper boundaries are formulated by solving an
optimization problem. Finally, two numerical examples are given to
verify the theory.
Sulfadiazine advanced oxidizing-degradation over Co-Cu LDH catalysts: Vacancy engineering and mechanism study
Authors: Guo Xiaoxi , Wu Hongyang , Hu Bo , Wang Ke , Wang Huanhuan , Li Bolan , Meng bo , Hu Tingting , Li Rui , Chen Jiali , Han Yi-Fan
Published: January 2024

A comprehensive study of advanced oxidation was conducted over Co-Cu
layered double hydroxide (LDH) catalysts, while the Co-Cu interaction
mechanism as well as oxygen vacancies (Ov) on the production of hydroxyl
radicals (•OH) were studied systemically using LRS, UV-Vis, XPS, EIS and
kinetics. Cu replacing Co sites in octahedral environment in α-Co(OH)2
could promote the oxidation of Co2+ by depressing the formation of
β-Co(OH)2. A Co4Cu1 LDH catalyst showed the highest sulfadiazine (SDZ)
removal efficiency of 93.7% from waste waters. The reaction mechanism
was assumed on the base of kinetics study of SDZ removal. The formation
of Co-O-Cu oxo-bridge in MO6 surroundings can enhance the generation of
ameliorated Ov, which improves the formation of surface hydroxyl for
H2O2 adsorption by boosting electron-transfer rate under the Co-Cu
interaction. This study paves a new way to the Fenton-Like catalysts
R&D, especially, orientating to the creation of active sites by vacancy
engineering.
A Novel Process to Recover Gypsum from Phosphogypsum
Authors: xiao junhui , lu tao , zhuang yuanfa , jin huang , zou kai
Published: January 2024

We investigated a coarse phosphogypsum containing 49.63% SO3, 41.41%
CaO, 10.68%, 4.47% SiO2, 1.28% P2O5, 0.11% F, 80.65% CaSO4·2H2O,
and whiteness of 27.68. Phosphogypsum contains calcium sulfate dehydrate
(CaSO4·2H2O) as the main mineral, with small amounts of brushite
(CaPO3(OH)·2H2O), quartz (SiO2), muscovite (KAl2SiO10(OH)), and zoisite
(Ca2Al3[SiO12]OH). Harmful elements such as silicon, phosphorus, and
fluorine are mainly concentrated in the +0.15 mm and −0.025 mm faction,
which can be pre-selected and removed by the grading method to further
increase the CaSO4·2H2O content. The test results show that a gypsum
concentrate with a CaSO4·2H2O purity of 98.94%, CaSO4·2H2O recovery of
80.02%, and whiteness of 37.05 was achieved using a direct flotation
method, which included one roughing, one scavenging, and two cleaning
operations, from −0.15 mm to +0.025 mm. The main mineral in the gypsum
concentrate was gypsum (CaSO4·2H2O), and limited amounts of muscovite
(KAl2SiO10(OH)) and zoisite (Ca2Al3[SiO12]OH) entered the gypsum
concentrate.
Plant invasion shifts soil microbiome and nutrient pools along altitudinal gradients
Authors: Hussain Khalid , Ahmad Rameez , Nuñez Martin , Dar Tanvir Ul , Rashid Irfan , Khuroo Anzar
Published: January 2024

Soil microbial communities, being at the interface of plant-soil
feedback systems, can play a pivotal role in facilitating ecosystem
response to the drivers of global environmental change, including
invasive alien species (IAS). Studies evaluating the effect of plant
invasion on soil microbial communities along altitudinal gradients can
provide novel insights regarding the spread and impact of IAS and
elevational range shifts in response to ongoing climate warming in
mountains. In this study, we used metagenomic tools to investigate the
impact of invasive Leucanthemum vulgare on taxonomic composition,
relative abundance, alpha and beta diversity of soil microbial
(bacterial and fungal) community, physicochemical properties and their
interaction between invaded and uninvaded plots selected across multiple
sites along an altitudinal gradient in Kashmir Himalaya. We found that
the invasion by L. vulgare shifted composition, relative abundance,
alpha and beta diversity of soil microbiome significantly in invaded
plots. The relative abundance of soil microbial communities
interestingly showed an increasing trend along the altitudinal gradient.
The soil physicochemical properties were significantly correlated with
microbial community abundance with temperature, K, pH, EC and Fe being
the dominant determinants. Also, we found a significant effect of soil
physicochemical properties on the microbial community abundance along
the altitudinal gradient. Our findings unravel the plant
invasion-induced shifts in the underground soil microbiome and
physicochemical properties, which improve our understanding of plant
invasion impacts on belowground biotic and abiotic components and can
contribute in guiding integrated management of invaded mountain
landscapes globally.
On a minimal set of generators for $H^*(BE_6; \mathbb F_2)$ in the generic degree $2^{s+3}-6$ and applications
Authors: KHAC Tin NGUYEN
Published: January 2024

Let $X$ be a topological space. Cohomology operations are generated by
the natural transformations of degree $i$ which are so-called Steenrod
squares
$Sq^{i}:H^{*}(X,\mathbb{F}_{2})\longrightarrow
H^{*+i}(X,\mathbb{F}_{2}),$ where
$H^{*}(X, \mathbb{F}_{2})$ is the singular
cohomology of $X$ with coefficients in the two-element field $
\mathbb{F}_{2},$ and $i$ is arbitrary
non-negative integers. The algebra of stable cohomology operations with
coefficients in $ \mathbb{F}_{2}$ is known as the
modulo 2 Steenrod algebra, $ \mathcal{A}.$ Let
$\mathcal P_n:=H^{*}\big(BE_n;
\mathbb F_2 \big) \cong
\mathbb
F_2[x_{1},x_{2},\ldots,x_{n}]$ be the
graded polynomial algebra over the prime field of two elements
$\mathbb F_2$, in $n$ generators $x_1, x_2,
\ldots , x_n$, each of degree 1, where $E_n$ is an
elementary abelian 2-group of rank $n,$ and $BE_n$ is the
classifying space of $E_n.$ We study the {\it hit
problem}, set up by Frank Peterson, of finding a minimal set of
generators for the polynomial algebra $\mathcal
P_{n},$ viewed as a module over the mod-2 Steenrod algebra
$\mathcal{A}$. This paper aims to explicitly
determine an admissible monomial basis of the
$\mathbb{F}_{2}$-vector space
$\mathbb{F}_{2}{\otimes}_{\mathcal{A}}\mathcal
P_{6}$ in the generic degree $2^{s+3}-6,$ with $s$ an
arbitrary non-negative integer. As an application of the above results,
we obtain the dimension results for the polynomial algebra
$\mathcal P_n$ in degree $d=
(n-1).(2^{n+u-1}-1)+\ell.2^{n+u},$ where $u$
is an arbitrary non-negative integer, $\ell =13,$ and
$n=7.$
Visualisation of the arterial valve morphology and number of leaflets in a fetus with common arterial trunk by Spatio-Temporal Image Correlation (STIC) imaging
Authors: Krishna Mani Ram , Sennaiyan Usha Nandhini
Published: January 2024

Spatio-temporal imaging correlation (STIC) technology has been employed
to visualize the fetal heart for close to two decades, but the
additional value of the technology remains debatable. The value of the
technology in identifying the morphology of the cardiac valves is being
recognized. We report a 21-week gestational age fetus with common
arterial trunk where STIC imaging enabled us to identify a bicuspid
arterial valve.
Detection of highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b in great skuas in Great Britain
Authors: Banyard Ashley C. , Lean Fabian Z.X. , Robinson Caroline , Howie Fiona , Tyler Glen , Nisbet Craig , Seekings James , Meyer Stephanie , Whittard Elliot , Ashpitel Henry F. , Bas Mehmet , Bryne Alexander M.P. , Lewis Tom , James Joe , Stefan Levon , Brown Ian H. , Hansen Rowena D. E. , Reid Scott M.
Published: January 2024

Highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b has been
detected in great skuas ( Stercorarius skua) across different
colonies on islands off the shore of Scotland, Great Britain during
summer 2021. Of eight skuas submitted for post-mortem examination, seven
have been confirmed as being infected with this virus using a range of
diagnostic assays. Here we overview the outbreak event that occurred in
this species, listed as species of conservation concern in Great
Britain.
LOGICAL CONSTRUCTION OF THE IONIZATION ENERGY THEORY AND THE ORIGIN OF PHYSICAL CATEGORIES
Authors: Arulsamy Andrew Das
Published: January 2024

Logical proofs and definitions are developed to establish (1) that the
energy-level spacings, ξ for each chemical element (from the periodic
table of chemical elements) can be converted to the ionization energies,
(2) both ξ and the ionization energies are unique, and (3) the averaged
ionization energy of any quantum matter is proportional to the averaged
ionization energy of its constituent chemical elements, if and only if ξ
≠ 0 and ξ is not an irrelevant constant. Physical atoms are then
constructed to define the physical sets such that these sets are members
of a specific physical class where each class belongs to a specific
physical category, P . However, there is not a single
structure-preserving functor from one energy-level spacing physical
category, ξ P to another ξ P ′ . Therefore, the existence of many ξ P
implies the existence of different categories of physical systems and
quantum matter. Subsequently, we shall prove that G o~̵̈ del’s
incompleteness theorem is a special case in physics such that the
propositions in a physical system can be made consistent and complete.
We exploit some of the propositions in ionization energy theory as our
‘microcanonical’ (sufficiently small) physical system.
Designing Network Topologies with Appropriated Bandwidth Management as Professional Resources to Support the Quality of Research and Higher Education to Initiate Covid-19 Effects in Mali
Authors: Cisse Abdramane , Triyono Mochamad Bruri
Published: January 2024

This paper presents a review of literature about the topic of
Integrating New Network Topologies with Appropriated Bandwidth
Management as Professional Resources to Support the Quality of Research
and Higher Education to Initiate the Covid-19 Effects in Mali. The
consensus admitted by all is the indispensability of Internet data
services in the sector of education and research especially in this
period of a breakout due to the coronavirus pandemic. The current paper
reviewed literature about the scope to support insights that will
contribute to raising the quality of research and higher education
through the integration of new network topologies and the appropriated
Internet data as professional resources to initiate the Covid-19 effects
in Mali. This research contributes to providing both teachers and
students with access to the internet with a personal user account, to
facilitate the adoption of blended learning through virtual learning
platforms and other relevant materials to complement their degrees
programs. Thanks to the integration of these technologies, Malian higher
education staff will get facilities to multiply their cooperation with
highly technology-integrated countries like Indonesia, Malesia,
Australia, and Korea.
The better can be the enemy of the good. The timing of LV venting during complex open-heart surgery revisited.
Authors: Ferraro Francesco , H Schlotterbeck , P Scharpf , S Demertzis , Theologou Thomas
Published: January 2024

We report a young female patient with a complex cardiac surgical history
that underwent a redo complex aortic valve replacement. In the context
of severe AR and dilated LV, we experienced that it is safer to start
the LV venting after aortic cross clamping. In this setting NIRS can be,
in this particular context, a useful monitoring tool to prevent
potential severe neurological damage.
Barycentric rational collocation method for semi-infinite domain problems
Authors: Li Jin
Published: January 2024

The barycentric rational collocation method for solving semi-infinite
domain problems is presented. Following the barycentric interpolation
method of rational polynomial and Chebyshev polynomial. Truncation
method and transformation method are presented to solve linear and
nonlinear differential equation defined on the semi-infinite domain
problems At last, three numerical examples are presented to test the
theoretical analysis.
Rhinoviruses restored while fighting the COVID-19 Pandemic in Guangzhou, China
Authors: Wu Di , Wu Tiantian , Zeng Qing , Chen Yiyun , Liu Yanhui , Lu Jianyun
Published: January 2024

Background To analyze the epidemic characteristics of the human
rhinovirus (HRV) outbreaks in Guangzhou, China, in 2020. Method
Descriptive epidemiological methods were used to analysis the HRV
related outbreaks of Guangzhou, 2020. Results 17 outbreaks were reported
in 2020 during the COVID-19 pandemic in Guangzhou, a total of 465
patients (290 males and 175 females) were enrolled, with a median age of
10. 223(47.96%) had been tested for HRV, 89 (39.91%) of which were
positive. 344/465 (73.98%) had fever, 138/465 (29.68%) had runny nose,
139/465 (29.89%) had sore throat, 86/465 (18.49%) had cough, 41/465
(8.82%) had headache, 37/465 (7.96%) had sneeze. Patients at age of 13
to 15 had the highest rate of sore throat and runny nose, patients at
the age of 11 to 12 had the highest rate of sneeze, and patients at age
of 12 to 14 had the highest rate of positive rate. Patients tested
positive had a higher rate of fever (2=11.271, P=0.001), cough
(2=6.987, P=0.008), runny nose (2=7.980, P=0.005) and sneeze
(2=4.676, P=0.031). Conclusion The HRV was restored during the fighting
the COVID-19 Pandemic. The conventional COVID-19 control measures were
not effective enough in preventing rhinovirus. More appropriate control
measures should be used to control HRV.
Dexamethasone Induced Avascular Necrosis in Pre-B Acute Lymphoblastic Leukemia Patient, a Brief Case Report
Authors: Zulfiqar Saad , Mujtaba Ghulam , Wali Rabia Muhammad , Siddiqui Adeel
Published: January 2024

We present a 5-year-old male patient who is being treated for acute
lymphoblastic leukemia and is on dexamethasone as a part of a
chemotherapy regimen. The patient presented to emergency department with
acute history of bilateral leg pain. MRI features are suggestive of
established grade 3 right femoral capital femoral avascular necrosis.
Dexamethasone was omitted from the patient’s future treatment and was
discharged on oral pain medication. The use of systemic corticosteroids
should be done under critical observation and both physician and patient
should be aware of the possibility of avascular necrosis.
A hybrid data-driven and physics-based model for temperature prediction of automotive exterior components
Authors: Chen Zhuoqian , XU houbao , Bai Yang , Liu Xiongjun , Yong Yingjing , Huo Huixia , Zhao Yiran
Published: January 2024

This paper constructs a hybrid data-driven and physics-based model for
temperature prediction of automotive exterior components based on
insufficient natural exposure experimental data. The hybrid model
consists of the physical part on heat conduction and the data-driven
part on artificial intelligence algorithms. The physical part is
developed by the heat balance equation, which ensures the generalization
ability of the model. The data-driven part is developed based on BP
neural network to calculate the unknown parameters and estimate the
missing weather data, which are necessary for the physical part. At the
end of the paper, the model performance is evaluated by the experiment
data. The numerical results illustrate that the hybrid model not only
has accurate predictive ability, but also possesses good generalization
capability.
Integrated cyto-physiological and proteomic analyses reveal new insight into CMS mechanism in a novel upland cotton CMS line LD6A
Authors: Najeeb Ullah , Zheng Jie , Khan Aziz , Bujin Zhou , Qiong Zhou , Xiangjun Kong , Yiding Liu , Liu Fang , Ruiyang Zhou
Published: January 2024

Cytoplasmic male sterile (CMS) system has extensively been used for
exploiting hybrid vigor in plant breeding programs. However, poor
understanding of molecular mechanism of fertility restoration in CMS is
still a major constraint for its application in many crops. Using
advanced analytical approaches, we elucidated the molecular pathways
regulating CMS induction and fertility restoration in cotton.
Reproductive structures of a novel CMS (LD6A) and its maintainer (LD6B)
line were analyzed physiological and proteomic responses. Significant
differential expression of proteins, such as Abrin, malate
dehydrogenase, malic enzyme, isocitrate dehydrogenase, histone
acetyltransferase was observed in novel CMS and its maintainer line.
Transmission electron micrographs of mitochondrial structure in anther
tapetum showed that the inner ridge of mitochondria in CMS line was
relatively indistinct than that of LD6B with narrower membranous space
at the tetrad stage. Further, relatively higher reactive oxygen species
were accumulated in the anther of CMS than its maintainer line at pollen
mother cell and tetrad stage. We suggest that abnormal sequence of
mitochondrial ribosome gene rps4 and rpl10 and high expression of
ribosome-inactivating protein gene Abrin in CMS line damaged
mitochondrial membrane and consequently induced pollen sterility. These
data provide new insight into CMS mechanism in cotton crops and a tool
to develop new CMS germplasm resources.
Functional and Morphological Disorders of Taste and Olfaction in COVID-19-Patients
Authors: Pavlidis Pavlos , Schittek Gregor , Fouka Evangelia , Spyridonidis Efstathios , Gouveris Haralampos
Published: January 2024

Objectives: To test the prevalence and evolution of acute olfactory and
gustatory functional impairment and of their morphologic correlates in
COVID-19 patients who require hospitalization due to COVID-19-related
respiratory conditions. Key-words: COVID-19, taste, olfaction,
electrogustometry, contact endoscopy Design: Electrogustometric (EGM) -
thresholds at the tongue area supplied by the chorda tympani, at the
soft palate and at the vallate papillae area were recorded bilaterally.
Olfaction was examined by Sniffin’ sticks. The patients’ nasal and oral
mucosa (fungiform papillae, fpap) were examined by contact endoscopy.
Setting: Tertiary referral medical centre. Patients: 53 consecutive
hospitalized patients (23 males, 30 females, age 42,54 ± 10, 95 yrs)
with RT-PCR-confirmed COVID-19 diagnosis were included. Patients have
been examined twice: just after hospital discharge and 4-6 weeks later.
Main outcome measures: EGM-thresholds and taste strips,
Schniffin-Sticks, Contact-Endoscopyesults: EGM-thresholds in patients
were significantly higher at both instances than those of healthy
subjects. EGM-thresholds at the second measurement were significantly
lower than those at the first measurement. Accordingly, patient-reported
gustatory outcomes were improved at the second measurement. The same
pattern has been found using Sniffin’ sticks. Significant alterations in
form and vascularization of fPap have been detected in patients,
especially at the first instance. Conclusions: COVID-19 affects both
gustatory and olfactory functions. It also affects in parallel the
structure and vascularization of both nasal and oral mucosa, although
the nasal mucosa to a much less, non-significant, extent. Our findings
suggest that COVID-19 may cause a mild to profound neuropathy of
multiple cranial nerves.