bluuebunny/crossref_metadata_2025 huggingface dataset:
Opportunity of lead-free metal halide perovskites for electroluminescence
Authors: Wang Zhibin , Zheng Song , Teng Qian , Li Chenhao , Zhuang Bin , Zhang Ruidan , Huang Feng , Chen Daqin , Yuan Fanglong
Published: June 2023

Lead halide perovskites (LHPs), which have demonstrated exceptional optical and electrical properties are promising candidates for electroluminescent light-emitting diodes (LEDs). However, concerns about the toxicity and stability have hindered their commercialization. In recent years, lead-free metal halide perovskites (LFMHPs) have emerged as promising alternatives, and significant progress has already been made in developing LFMHP-based LEDs. Nevertheless, their device performance is still inferior to that of well-developed LHP-based counterparts. To fully exploit LED applications and boost device performance, in this review, we provide a comprehensive overview of the currently explored different metal-based LFMHPs. We mainly focus on the preparation methods, crystal structure, optical properties, and LED applications of these materials. Furthermore, we conclude with a discussion regarding the key challenges and potential prospects in this field. We hope that this review will inspire more extensive research on LFMHPs from a new perspective and promote practical applications of LFMHP-based LEDs in multiple directions of current and future research.
Breves apontamentos sobre a liberdade de expressão
Authors: Álvaro Ricardo de Souza Cruz  , Clarissa Aguilar Magalhães  , Sophia Galbas Rezende
Published: June 2023

A liberdade de expressão é um direito fundamental presente na Constituição de 1988 e funciona como um princípio fundamental para a democracia. Corolária do direito fundamental à liberdade, possui uma grande extensão quanto ao seu significado, sendo elemento base para outros diversos direitos e garantias, como o direito à informação e à liberdade de imprensa. No entanto, a liberdade de expressão pode sofrer algumas limitações, torna-se importante discriminar de modo mais sistemático tal limitação. Não se busca no presente trabalho o esgotamento do tema, mas sim a demonstração de sua grandeza e amplitude por meio de uma seleta bibliografia sobre o tema, como pesquisas, obras acadêmicas de variados tipos desde livros a outros artigos científicos, notícias e reportagens e paralelos do direito brasileiro por meio do direito comparado com precedentes americanos, alemães e espanhóis. Assim percebe-se que a liberdade de expressão está amalgamada a qualquer democracia e sem seus fundamentos, não é possível ter um Estado Democrático de Direito no mundo contemporâneo.
美国高等教育发展的五个趋势
Authors: LIU OU LYDIA
Published: June 2023

由于科技进步、自动化和学生人口结构的改变，高等教育的格局发生了重大变化，而疫情则使该情况进一步复杂化。在本文中，我将讨论高等教育发展的五个趋势：(a) 高校和企业在教育培训领域平行赛道的出现，(b) 多元化教育方式的普及以及教学上时间和场所的进一步分离，(c) 精英大学和普通院校之间在学生入学和流失上的两极分化，(d) 招生中的公平和多样性，以及 (e) 国际教育的新常态。这五个趋势将显著影响高等教育的评估、运营和改革方式。
La traducción de la ironía en el discurso Sobre la Corona de Demóstenes
Authors: Fornieles Sánchez Raquel
Published: June 2023

El propósito de este trabajo es ofrecer una aproximación a la traducción al español de la ironía en la obra maestra de Demóstenes —el discurso Sobre la Corona— en el marco de los ataques verbales que el orador dirige a su gran rival político, Esquines.
Animaux et figurations animales
Authors: Pouillard Violette , Coiffet Anne-Sophie
Published: June 2023

Le tournant animal imprime depuis plusieurs décennies sa marque en sciences humaines et sociales. Le présent dossier, qui place au centre du propos les figurations littéraires, picturales, cinématographiques des animaux, et les animaux qu’elles dépeignent, entend s’emparer de quelques-uns des questionnements historiographiques et épistémologiques associés à leur intégration aux études animales.
“Je ne sçai quoi”. On Animal Imagery, Evolution and Beauty
Authors: Bredekamp Horst , Thurner Kolja
Published: June 2023

The essay tries to plea for incorporating concepts of evolutionary and animal imagery into an open theory of the image, that extends beyond the realm of human artifice and must no longer be viewed with an anthropocentric focus. Turning to images that are not human-made, we try to explore different image phenomena and connect them to non-human concepts of “Beauty” as historically developed by Charles Darwin’s underappreciated theory of “Sexual Selection” and, before him, trailblazed by William Hogarth.
The ‘Strange Kinship’ of Interanimality. Vision, Visibility and Lifeworlds in Science and Art
Authors: Daly Anya
Published: June 2023

The sovereign gaze of the human subject has predominated in natural science and aesthetics across representations of animality and animal lifeworlds. Nonetheless, exceptions to such sovereign gazes, characterised by distantiation, hierarchies, dichotomies of gazer and gazed-at, are found in the work of von Uexküll and da Vinci, in the exceptional quality of attention they bring to their tasks; a transformative attention, revealing as Merleau-Ponty describes “a strange kinship” of interanimality.
Snake Eyes. A Natural History of Picturing, Perception, and the Serpents That Lurk Within
Authors: Yang Andrew S.
Published: June 2023

Snakes capture us like no other creature. As serpents, dragons, and ouroboroi, their potency as symbols complicates their objective portrayal. Meanwhile, research suggests that serpentine shapes are present as ciphers within our visual circuitry before we ever even see them. From traditions of natural history to present-day neurobiology, there may be no way to depict snakes that is not also deeply imaginary.
Représentation animale, réflexion et dialectique
Authors: Coiffet Anne-Sophie
Published: June 2023

Cet article examine les jeux de reflets à l’oeuvre entre les humains, les animaux et leurs représentations. Il met en perspective l’idée développée par Graham Harman selon laquelle le spectateur et l’oeuvre d’art constituent un nouvel objet les incluant tous deux. Cet objet immersif incite le sujet humain à ajuster, le temps de l’expérience esthétique, son regard sur l’animal et à envisager la forme dialogique de leur rencontre.
ПОПИС НЕОБЈАВЉЕНИХ ЧЛАНАКА ЕДИЦИЈЕ ,,СРЕДЊА БОСНА У НОБˮ
Authors: ТОПИЋ ДАРИО
Published: June 2023

Рад на азбучном сређивању шест фасцикли у којима се налазе чланци и сјећања на период Другог свјетског рата, пронађених у архиви Oпштине Прњавор, свједоче, прије свега, о запостављености грађе која, истина прожета идеолошком доктрином и неослобо-ђена атрибута супериорности, значаја и праведне борбе партизанског покрета у односу на дру-ге војске које су се у то вријеме кретале по Босни и Херцеговини и Југославији, ипак има свој значај и тежину, најприје са аспекта проучавања локалне историје, потом регионалне, а онда и опште историје. У раду су дати азбучни попис аутора и радни називи објављених и необјавље-них чланака прикупљаних за шест књига едиције Средња Босна у НОБ. Имајући у виду очува-ност и број аутентичних, изворних докумената које су издавале административне службе и органи многобројних војски које су се кретале овим простором у вријеме Другог свјетског рата, овакав вид грађе понекад представља и једини кроз који се може нешто сазнати о тим турбу-лентним временима.
JAVNE APOTEKE U SARAJEVU U AUSTROUGARSKOM PERIODU
Authors: MARKOVIĆ-PEKOVIĆ VANDA
Published: June 2023

Rad predstavlja javne, građanske apoteke koje su otvorene u Sarajevu u periodu austrougarske vladavine. Uspostavljanjem austrougarske uprave uređuje se apotekarska djelatnost i počinje otvaranje većeg broja javnih, građanskih apoteka. Koncesije za otvaranje apoteke većinom su dobijali stranci, jer domaćih apotekara nije bilo. Prva moderna apoteka u ovom periodu je otvorena 1878, a posljednja 1913. godine. U periodu 1898–1918. u gradu su otvorene samo dvije nove apoteke, a tokom četrdeset godina austrougarske vladavine radilo ih je ukupno sedam. Apoteke su često reklamirane u raznim publikacijama kao dobro snabdjevene svim potrebnim lijekovima i drugim proizvodima, kao što su kozmetika, pića, fotografski pribor. Apotekari su svojim radom doprinijeli unapređenju zdravstvene zaštite u gradu, kao i građanskoj kulturi i opštem razvoju društva zajedno sa svojim savremenicima.
ПОЛИТИКА САВРЕМЕНЕ ТУРСКЕ НА БАЛКАНУ И СРПСКА ЈАВНОСТ
Authors: МИКИЋ ЂОРЂЕ
Published: June 2023

Српску јавност и политику може да занима поређење политике савреме-не Турске и оне из старих султанских времена или револуционарног времена председника Кемала Ататурка. У том интересовању централно место заузима питање промена у односу на политику председника Ататурка и њене циљеве на Балкану, са којег је војнички потиснута у балканским ратовима. Српску јавност посебно занима судбина Ататуркових реформских резултата, чији гарант је била турска армија. То интересовање је 1946. појачано пошто је тада успоста-вљен вишестраначки систем у којем су новонастале исламистичке партије биле толерантне, мада се данас, 75 година после, може говорити о циклусима који су се понављали и чинили да турско друштво буде растрзано између секуларизма, који је земљи у аманет оставио Кемал-паша Ататурк, и идеологија које се поја-вљују.
In memoriam РАДЕ МИХАЉЧИЋ
Authors: СМИЉАНИЋ АРАНЂЕЛ
Published: June 2023

У четвртак 26. марта 2020, послије дуге и тешке болести, умро је наш професор, колега и при-јатељ Раде Михаљчић. Криза изазвана корона виру-сом спријечила нас је да присуствујемо сахрани која је обављена неколико дана касније на Бежаниј-ском гробљу у Београду. Чињеница да нисмо могли присуствовати сахрани (број присутних био је огра-ничен на пет) додатно нас је погодила. In memoriam је прилика да прикажемо животни пут нашег покој-ног професора. У питању је тежак и незахвалан посао, јер је готово немогуће на неколико страница приказати сва његова достигнућа, успјехе и награ-де, при чему се не смије занемарити ни његова лич-ност, која је, по много чему, била непоновљива.
IZGRADNJA PUTNE MREŽE U VRIJEME AUSTROUGARSKE UPRAVE: PUT BANJA LUKA - JAJCE (1892–1896)
Authors: BOŽIĆ JELENA
Published: June 2023

Predmet prezentovanih istraživanja je izgradnja državnog puta Banja Luka – Jajce, koji je u prvom dijelu rada posmatran u kontekstu organizacije građevinske službe i zakonodavstva u oblasti izgradnje i održavanja puteva, sa posebnim osvrtom na obavezu kuluka. Trasiran na nepovoljnom brdsko-planinskom terenu, za čije je savladavanje bilo potrebno izgraditi mostove, galerije i tunele, ovaj put 1. klase predstavlja izvanredan građevinski poduhvat koji je realizovan 18921896. zahvaljujući iskusnim inženjerima Zemaljske vlade Bosne i Hercegovine na čelu sa Edmundom Stixom. Izgradnjom ovog puta dugog 72 km Banja Luka je povezana sa glavnim gradom Sarajevom i morem, a preko Gradiške sa Bečom. Lakši i brži saobraćaj ljudi i dobara podstakao je i unaprijedio mnoge privredne grane. Izgradnja ove i danas važne saobraćajnice (magistralni put M 16) trasirane kroz izuzetno atraktivan prirodni pejzaž dolinom Vrbasa, sa nizom značajnih srednjovjekovnih gradova i drugih graditeljskih spomenika, bila je preduslov za početak i razvoj turizma u ovom dijelu zemlje.
Two Safaitic Inscriptions in Comparison to Geographical and Historical Sources about the Arabian Expedition of Aelius Gallus
Authors: Magnelli Adalberto , Petrantoni Giuseppe
Published: June 2023

The aim of this work is to analyse the critical cruces about some geographical locations in reference to the western coast and the inland parts of the South Arabian and Nabataean area. In detail, the purpose of this research is to investigate the probable location of the port of Leuke Kome through a comparison between an epigraphic source written in Safaitic and some indication in Strabo’s account of the expedition of Aelius Gallus to Arabia Felix. In addition, a new reading of another Safaitic inscription mentioning a curious S1ly (Silleus?) could help to better understand some details of the Roman Arabian campaign too.
Proposta de diretrizes para uma boa gestão de suprimentos no setor de saúde
Authors: Riguette Thalia Ouverney , De Stefano Ercilia , Freitag Alberto Eduardo Besser , Maia Robinson Magalhães , Santana Walter Aloisio , Barreto João Carlos , Picoli Marcos Antonio , Braga Sueli Mello , Pereira Mauro Henrique da Silva
Published: June 2023

O setor de a saúde trabalha com a vida, o maior valor que se tem. Para que o serviço seja realizado com êxito, as organizações hospitalares necessitam de uma boa gestão de seus suprimentos para que possam atender às demandas de maneira eficiente. Com base nesse contexto, o objetivo deste estudo é propor diretrizes para uma boa gestão de suprimentos no setor de saúde. A metodologia pode ser classificada como pesquisa de natureza básica, com objetivo exploratório, desenvolvida por meio de um estudo bibliométrico e revisão sistemática da literatura, baseada no protocolo prisma. A partir dos resultados da bibliometria de 119 registros, observou-se uma tendência de crescimento sobre o tema saúde nos últimos cinco anos, principalmente em função das preocupações com a pandemia do covid-19, justificando esta pesquisa. No que tange os 14 estudos incluídos na revisão da litertura, identificou-se que em 2021 foram publicados sete trabalhos, seguido de 6 trabalhos em 2020, reforçando a atual importância da gestão de suprimentos na saúde. A partir da análise qualitativa dos artigos, elaborou-se uma proposta de diretrizes para uma boa gestão de suprimentos no setor de saúde, englobando riscos, planos de contingência, resiliência e valorização dos profissionais.
Determinantes da governança orçamentária: uma proposta de framework
Authors: Da Silva Jorge Cleber Pereira , Do Nascimento João Carlos Hipólito Bernardes
Published: June 2023

Em razão das perspectivas de consolidação fiscal e busca de qualidade do gasto público, a agenda de estudos no campo da governança orçamentária tem se mostrado necessária e fortemente alinhada aos atuais desafios da gestão pública brasileira. Entretanto, o desenvolvimento de modelos explicativos sobre esses determinantes no contexto brasileiros é pouco explorado. Deste modo, o estudo propõe um framework teórico para a análise dos determinantes da governança orçamentária. Utilizou-se de pesquisa bibliográfica tendo descritores as expressões transparência, participação, sustentabilidade, integridade, planejamento e governança orçamentária. O estudo defende a integração dos determinantes teóricos encontrados e a testagem do modelo empírico proposto.
Gestão municipal de drenagem e manejo de águas pluviais: avaliação dos impactos decorrentes da urbanização na Cidade Nova, Ilhéus-BA
Authors: Teixeira Niel Nascimento , Araújo Alisson Victor Souza
Published: June 2023

A implantação de assentamentos urbanos no Brasil tem desconsiderado aspectos importantes para o saneamento ambiental das cidades. Um desses aspectos é o impacto provocado pelos sistemas de drenagem urbana nas bacias e cursos d’água. Apesar da existência de importantes estudos para subsidiar a elaboração de projetos sustentáveis para esses sistemas de drenagem urbana, onde é considerada a minimização dos danos à conservação do ciclo hidrológico, as obras e a gestão municipal dos sistemas têm, via de regra, desconsiderado as premissas adotadas nos estudos e provocado os mesmos danos ambientais dos projetos convencionais. Deste modo, o objetivo principal deste trabalho é o de avaliar os impactos decorrentes da urbanização no sistema de drenagem pluvial urbana no bairro Cidade Nova do município de Ilhéus-BA, analisando as condições atuais do seu sistema de drenagem pluvial, identificando os principais impactos da urbanização no seu sistema de drenagem, e propondo a implementação de medidas sustentáveis de forma a minimizar os impactos ambientais, o que redundará numa significativa melhoria na gestão do município no quesito de drenagem e manejo de águas pluviais. Para consecução deste objetivo, analisou-se as condições atuais do seu sistema de drenagem pluvial e, identificou-se os principais impactos da urbanização neste sistema. Ao final, propõe-se a implementação de medidas sustentáveis de forma a minimizar os impactos ambientais e a otimizar a gestão municipal.
National Cancer Institute Centers With Environmental Sustainability Plans for Climate Change
Authors: Lichter Katie E. , Weinstein Hannah N. W. , Husain Marium , Kishan Raina , Hantel Andrew , Maniar Ashray
Published: June 2023

This qualitative study investigates environmental sustainability plans at National Cancer Institute Comprehensive Cancer Centers and affiliated institutions.
Soft Magnetic Properties and Electromagnetic Shielding Performance of Fe40Ni40B20 Microfibers
Authors: Sharifikolouei Elham , Żywczak Antoni , Sarac Baran , Kozieł Tomasz , Rashidi Reza , Bala Piotr , Fracasso Michela , Gerbaldo Roberto , Ghigo Gianluca , Gozzelino Laura , Torsello Daniele
Published: June 2023

Fe40Ni40B20 metallic glass is a key material among the many amorphous systems investigated thus far, owing to its high strength and appealing soft magnetic properties that make it suitable for use as transformer cores. In this study, Fe40Ni40B20 microfibers are fabricated down to 5 µm diameter. Three different melt–spinning wheel velocities: ≈51 m s−1, ≈59 m s−1, and ≈63 m s−1 (MG1, MG2, MG3) are used. Their fully amorphous structure is confirmed using X–ray diffraction, and differential scanning calorimetry (DSC) traces reveal a larger relaxation profile for the higher–quenched microfiber. Vibrating sample magnetometer measurements showed a higher saturation magnetization of 136 emug−1 for annealed metallic glass microfibers with a wheel velocity of 59.66 ms−1. Cylindrical magnetic field shields are obtained by aligning and wrapping the fibers around a cast. The observed anisotropic static field shielding behavior is in accordance with the microfibers' anisotropic nature. Composite samples are also produced by embedding the microfibers in an epoxy matrix to investigate their electromagnetic properties at GHz frequencies. Inclusion of the microfibers increase the composite's attenuation constant by 20 to 25 times, making it an ideal candidate for applications in the communications frequency range.
Immigrant generation status and its association with pubertal timing and tempo among Hispanic girls and boys
Authors: Houghton Lauren C. , Paniagua‐Avila Alejandra , Hua Simin , Terry Mary Beth , McDonald Jasmine A. , Ulanday Kathleene T. , van Horn Linda , Carnethon Mercedes R. , Isasi Carmen R.
Published: June 2023

Purpose

In the United States, Hispanic‐Latino children reach puberty earlier on average than non‐Hispanic white children. Yet among U.S. Hispanic/Latino children, pubertal timing comparisons between immigrant generations have not been made, hence we examined whether pubertal timing differs by immigrant generational status, independent of BMI and acculturation measures.

Methods

Cross‐sectional data on 724 boys and 735 girls, aged 10–15 years, from the Hispanic Community Children's Health Study/Study of Latino (SOL) Youth, were used to predict the median ages of thelarche, pubarche, and menarche in girls, and pubarche and voice change in boys, using Weibull survival models, while adjusting for SOL center, BMI, and acculturation.

Results

In girls, the first generation began thelarche earlier than second and third generations (median age [years] [95% confidence interval]: 7.4 [6.1, 8.8] vs. 8.5 [7.3, 9.7] and 9.1 [7.6, 10.7], respectively), but began menarche later (12.9 [12.0,137] vs. 11.8 [11.0, 12.5] and 11.6 [10.6, 12.6], respectively). Pubertal timing and tempo for boys did not differ by generational status.

Conclusions

First‐generation U.S. Hispanic/Latino girls had the earliest thelarche, latest menarche and longest pubertal tempo, compared to second and third generations. Factors beyond BMI and acculturation may account for the differences in pubertal timing by generational status of U.S. Hispanic/Latino girls.
A novel biallelic frameshift variant in C2orf69 causing developmental regression, seizures, microcephaly, autistic features, and hypertonia
Authors: Werren Elizabeth A. , Srinivasan Varunvenkat M. , Gowda Vykuntaraju K. , Pandey Akanksha , Vaish Saurabh , Kabbur Anusha Raj , Nandeesh Bevinahalli N. , Srivastava Anshika
Published: June 2023

Combined oxidative phosphorylation deficiency type 53 (COXPD53) is an autosomal recessive neurodevelopmental disorder (NDD) caused by homozygous variants in the gene C2orf69. Here, we report a novel frameshift variant c.187_191dupGCCGA, p.D64Efs*56 identified in an individual with clinical presentation of COXPD53 with developmental regression and autistic features. The variant c.187_191dupGCCGA, p.D64Efs*56 represents the most N‐terminal part of C2orf69. Notable clinical features of COXPD53of the proband include developmental delay, developmental regression, seizures, microcephaly, and hypertonia. Structural brain defects of cerebral atrophy, cerebellar atrophy, hypomyelination, and thin corpus callosum were also observed. While we observe strong phenotypic overlap among affected individuals with C2orf69 variants, developmental regression and autistic features have not been previously described in individuals with COXPD53. Together, this case expands the genetic and clinical phenotypic spectrum of C2orf69‐associated COXPD53.
Extraction of phospholipids from beta‐serum using switchable solvents and solid‐phase extraction
Authors: Rathnakumar Kaavya , Ortega‐Anaya Joana , Jimenez‐Flores Rafael , Martínez‐Monteagudo Sergio I.
Published: June 2023

We report the extraction of milk phospholipids (MPLs) from beta‐serum with a tertiary amine (N‐N dimethylcyclohexylamine, CyNMe2). The extraction time (3, 10, and 18 h), temperature (25, 40, and 60°C), and sample‐to‐solvent ratio (1/3, 1/10, and 1/18 v/v) were evaluated according to a factorial design. The extracted lipids were fractionated with solid‐phase extraction and quantified by HPLC‐CAD. Extraction conducted at 60°C yielded values of 14.86 ± 2.95%, 69.79 ± 3.19%, 79.39 ± 5.55% after 3, 10, and 18 h and a ratio of 1/18 (w/w). Microstructure images showed significant damage to the solid matrix that released the inner MPLs into the aqueous medium. The highest extraction yields of MPLs (79.39 ± 5.55%) were obtained after 18 h of extraction at 60°C and a sample‐to‐solvent ratio of 18 (w/w). The recovered fraction was made of phosphatidylinositol (~41%), phosphatidylserine (~6%), phosphatidylethanolamine (~34%), phosphatidylcholine (~9%), and sphingomyelin (~8%). This work outlines different extraction conditions for recovering MPLs from beta‐serum, a dairy byproduct.
Preparation and mechanical properties of graphite nanosheet/nylon 610 nanocomposites using graphite nanosheets treated with supercritical water
Authors: Lim Jun‐Ven , Bee Soo‐Tueen , Sin Lee Tin , Ratnam Chantara Thevy , Bee Soo‐Ling
Published: June 2023

In this study, water at high temperature (175°C) and in vacuum state (−1 bar) is applied to graphite nanosheets to enhance surface activity through the formation of oxygen functionalities via supercritical water treatment. The nylon 610 nanocomposites (with treated or untreated nanosheets as nanofillers) was then synthesized using interfacial polymerization. X‐ray diffraction (XRD) analysis showed that the water treatment had not altered the crystal structure of the graphite nanosheets. On average, the Young's modulus and tensile strength of the nanocomposites are larger than the pure nylon 610 created, with the highest Young's modulus and tensile strength obtained being 137.44 MPa and 930.49 kPa, respectively. The tensile strength of treated nanosheets/nylon nanocomposites generally decreased with increasing wt%; while, that of untreated nanosheets/nylon nanocomposites increased with increasing wt%. This enhancement in mechanical properties can be attributed to the functionalization of graphite nanosheets, which may yield a slight oxidation on its surface, allowing for stronger interaction between the nylon 610 matrix and the nanosheets. Fourier transform infrared (FTIR) spectra also showed the presence of hydrogen bonding between the carbon nanofillers and the polymer matrix through the appearance of amide bands. Furthermore, scanning electron microscopy (SEM) showed that at higher wt%, aggregation will occur, which may lead to a weakening in physical properties. Nevertheless, this improvement in mechanical properties when compared with pure nylon 610 can be attributed to the intact structure of the nanosheets and the chemical bonding between the nanofillers and nylon 610.
Successful treatment of orbital Langerhans cell histiocytosis with stereotactic radiosurgery: A case report and literature review
Authors: Etter Emily , Bosse Benjamin , Wang Yi Peng , Hiniker Susan , Oh Justin
Published: June 2023

Key Clinical Message

Langerhans cell histiocytosis (LCH) is a rare inflammatory myeloid neoplasm arising from the proliferation of pathologic Langerhans cells. LCH has a spectrum of presentations predominantly affecting male pediatric patients. As LCH is a relatively uncommon diagnosis, there is no standard of care for treatment of the disease and treatment is based largely on clinical judgment, lesion characteristics, and symptoms at presentation. Here we present a case of unifocal, isolated orbital LCH in a 19‐year‐old young man treated initially with surgical resection. Follow‐up imaging 2 months later demonstrated significant regrowth of the mass and no other sites of disease. The recurrent orbital disease was treated with stereotactic radiosurgery (SRS) to 7 Gy in one fraction. Near complete resolution of the mass was achieved with no recurrence after 1.5 years of follow‐up. SRS for treatment of orbital LCH is a novel treatment not previously described in the literature which may provide benefit in select cases.
Recurrent bicycle falls by an elderly man who developed multiple intramuscular abscesses associated with urine leakage secondary to posterior urethral injury caused by pelvic ring disruption
Authors: Matsumoto Yoko , Tanno Keisuke , Nakamura Yuhei , Hamamoto Kohei , Yoshihara Hanako , Fukuchi Takahiko , Oyama‐Manabe Noriko , Sugawara Hitoshi
Published: June 2023

Key Clinical Message

With the aging of the population, physicians need to pay more attention to assessing the presence or absence of pelvic fractures and urinary retention associated with urethral injury due to such fractures in the elderly when falling from bicycles.

Walking ability does not rule out the presence of pelvic fractures. Many geriatric patients are likely to fall off bicycles. Physicians should pay more attention when assessing complications related to urethral trauma caused by pelvic fractures in the elderly after falling from bicycles.
Crystal Structure and Photocatalytic Properties of the CsV0.625Te1.375O6 Mixed‐Valence β‐Pyrochlore Compound
Authors: Fukina Diana G. , Shotina Valeria A. , Boryakov Aleksey V. , Zubkov Sergey Yu. , Telegin Sergey V. , Volkova Natalia S. , Fukin Georgy K. , Shilova Elena V. , Suleimanov Evgeny V.
Published: June 2023

A new β‐pyrochlore compound with complex composition of Cs(V3+0.0625V5+0.5625Te4+0.34375Te6+1.03125)O6 has been synthesized by a solid‐state reaction and characterized by single‐crystal X‐ray diffraction and thermal analysis. The compound possesses the typical cubic symmetry with space group
, however some of the oxygen atoms shift from the special position 48 f to the general crystallographic positions 32e, 96 g and 96 h. This shift is caused by complex B‐site composition with mixed‐valence vanadium and tellurium atoms, especially the presence of the large Te4+ ion. The locations of the valence band and conduction band edges were determined experimentally under vacuum conditions by X‐ray photoelectron spectroscopy, UV‐visible and impedance spectroscopy and evaluated theoretically for water solutions. The photocatalytic ability of the compound under visible light irradiation was determined using the methylene blue decomposition process as an example. The nature of the active radical species and possible dye degradation pathway were suggested according to experimental data.
Protocol of the Double‐Click Seq Method to Evaluate the Deposition Bias of Chromatin Proteins
Authors: van der Wouden Petra E. , Zwinderman Martijn R. H. , Chen Deng , Borghesan Michela , Dekker Frank J.
Published: June 2023

Symmetrical deposition of parental and newly synthesized chromatin proteins over both sister chromatids is important for the maintenance of epigenetic integrity. However, the mechanisms to maintain equal distribution of parental and newly synthesized chromatid proteins over sister chromatids remains largely unknown. Here, we describe the protocol for the recently developed double‐click seq method that enables mapping of asymmetry in the deposition of parental and newly synthesized chromatin proteins on both sister chromatids in DNA replication. The method involved metabolic labeling of new chromatin proteins with l‐Azidohomoalanine (AHA) and newly synthesized DNA with Ethynyl‐2′‐deoxyuridine (EdU) followed by two subsequent click reactions for biotinylation and subsequently by corresponding separation steps. This enables isolation of parental DNA that was bound to nucleosomes containing new chromatin proteins. Sequencing of these DNA samples and mapping around origins of replication in the cellular DNA enables estimation of the asymmetry in deposition of chromatin proteins over the leading and lagging strand in DNA replication. Altogether, this method contributes to the toolbox to understand histone deposition in DNA replication. © 2023 The Authors. Current Protocols published by Wiley Periodicals LLC.

Basic Protocol 1: Metabolic labeling with AHA and EdU and isolation of nuclei

Basic Protocol 2: First click reaction, MNase digestion and streptavidin enrichment of labeled nucleosomes

Basic Protocol 3: Second click reaction, Replication‐Enriched Nucleosome Sequencing (RENS) Protocol
Fusion of artificial intelligence and game theory for resource allocation in non‐orthogonal multiple access‐assisted device‐to‐device cooperative communication
Authors: Rathod Tejal , Gupta Rajesh , Kumar Jadav Nilesh , Tanwar Sudeep , Alabdulatif Abdulatif , Sharma Ravi
Published: June 2023

Device‐to‐device (D2D) communication offers a low‐cost paradigm where two devices in close proximity can communicate without needing a base station (BS). It significantly improves radio resource allocation, channel gain, communication latency, and energy efficiency and offers cooperative communication to enhance the weak user's network coverage. The cellular mobile users (CMUs) share the spectral resources (e.g., power, channel, and spectrum) with D2D mobile users (DMUs), improving spectral efficiency. However, the reuse of radio resources causes various interferences, such as intercell and intracell interference, that degrade the performance of overall D2D communication. To overcome the aforementioned issues, this paper presents a fusion of AI and coalition game for secure resource allocation in non‐orthogonal multiple access (NOMA)‐based cooperative D2D communication. Here, NOMA uses the successive interference cancellation (SIC) technique to reduce the severe impact of interference from the D2D systems. Further, we utilized a coalition game theoretic model that efficiently and securely allocates the resources between CMUs and DMUs. However, in the coalition game, all DMUs participate in obtaining resources from CMUs, which increases the computational overhead of the overall system. For that, we employ artificial intelligence (AI) classifiers that bifurcate the DMUs based on their channel quality parameters, such as reference signal received power (RSRP), received signal strength indicator (RSSI), signal‐to‐noise ratio (SNR), and channel quality indicator (CQI). It only forwards the DMUs that have better channel quality parameters into the coalition game, thus reducing the computational overhead of the overall D2D communication. The performance of the proposed scheme is evaluated using various statistical metrics, for example, precision score, accuracy, recall, F1 score, overall sum rate, and secrecy capacity, where an accuracy of 99.38% is achieved while selecting DMUs for D2D communication.
Ecological momentary assessment of mood regulation eating expectancies in eating disorders: Convergent and predictive validity
Authors: Mason Tyler B. , Crosby Ross D. , Engel Scott G. , Morales Jeremy C. , Wonderlich Stephen A.
Published: June 2023

Objective

Eating expectancies (EE) are the anticipation of various benefits or detriments from eating, with mood regulation being a salient type of EE associated with eating disorders. This study examined the convergent and predictive validity of ecological momentary assessment (EMA) mood regulation EE items, including mood improvement and mood worsening EE.

Methods

Thirty women with binge‐eating pathology completed a 14‐day EMA protocol, which included measures of mood regulation EE, affect, appetite, appearance‐ and body‐related factors and disordered‐eating behaviours.

Results

Greater within‐subjects hunger and lower within‐subjects positive affect and fullness were related to elevated mood improvement EE. Higher within‐subjects appearance concerns, fullness, body social comparisons and thinness pressure were associated with higher mood worsening EE. Greater within‐subjects mood worsening EE predicted greater likelihood of vomiting at the subsequent time point, but there were no within‐subjects associations between mood improvement EE and behaviours. Yet, greater between‐subjects mood worsening EE were associated with more restraint/restriction and binge eating, and greater between‐subjects mood improvement EE were associated with more binge eating.

Conclusions

Findings support the convergent validity of EMA mood regulation EE items. There was limited predictive validity evidence, suggesting complexities in how mood regulation EE predict behaviour in daily life.
An intensive longitudinal investigation of maternal and infant touching patterns across context and throughout the first 9‐months of life
Authors: Mercuri Marisa , Stack Dale M. , De France Kalee , Jean Amélie D. L. , Fogel Alan
Published: June 2023

Touch is a central component of mothers’ and infants’ everyday interactions and the formation of a healthy mother‐infant relationship. Twelve mothers and their full‐term infants from the Midwest, USA participated in the present study, which examined the quality and quantity of their touching behaviors longitudinally at 1‐, 3‐, 5‐, 7‐, and 9‐months postpartum and within two normative interaction contexts (face‐to‐face, floor play). Findings revealed that mothers’ and infants’ individual touch patterns, varied according to context, infant age (time), and the specific type of touch examined. At 1‐month postpartum, dyads coordinated their touch via behavioral matching and were especially reliant on rudimentary types of touch with soothing and regulatory properties (static/motionless touch, stroking). As infants aged to 9‐months, dyads transitioned to a more complex form of tactile synchrony characterized by the parallel use of complementary types of touch (grasp, poke, pull). This evolution of tactile synchrony may reflect infants’ growing behavioral repertoire and increased capacity to use more refined forms of touch. To our knowledge, this study was the first of its kind, uniquely contributing to the scant knowledge about the development of mother‐infant touch and synchrony and offering direct implications for early care practices and infant health and well‐being.
Adaptive 3D noise level‐guided restoration network for low‐dose positron emission tomography imaging
Authors: Li Wenbo , Huang Zhenxing , Zhou Chao , Zhang Xu , Fan Wei , Liang Dong , Hu Zhanli
Published: June 2023

Many deep learning methods have been proposed to improve the quality of low‐dose PET images (LPET), which usually construct end‐to‐end networks with certain radiation dose inputs. However, these approaches have omitted the noise disparity in PET images, which may differ among manufacturers or populations. Therefore, we tend to exploit these noise differences among PET images to achieve adaptive restoration. We proposed a 3D noise level‐guided PET restoration network for LPET including (1) adaptive noise level‐aware subnetwork and (2) LPET restoration subnetwork. The first subnetwork aims to predict the noise level of the given LPET, while the second subnetwork treats the estimated noise level as a priori information to guide the restoration process from LPET to standard‐dose PET images. Experiments were performed on real human head and neck datasets while the peak signal‐to‐noise ratio and structural similarity index measure were used to evaluate LPET recovery performance. Moreover, we also compared the proposed network with several deep‐learning approaches. Experimental results demonstrate that our network with dual‐stage design can perform adaptive restoration for LPET, yielding better visual and quantitative results. In future work, we attempt to apply our method to other imaging tasks and adapt it for clinical practice.
Identification of a novel cuproptosis‐related gene signature for rheumatoid arthritis—A prospective study
Authors: Hu Han , Dou Xinyu , Hu Xiangjia , Wang Linbang , Ma Yunlong , Liu Jingkun , Zhou Xuchang , Cao Hong , Liu Xiaoguang , Deng Xiaoming , Li Nan
Published: June 2023

Background

Rheumatoid arthritis (RA) is a multifactorial systemic autoimmune disease characterized by ongoing synovial inflammation, leading to the degradation of cartilage. Cuproptosis, as a newly characterized form of cell death, may influence RA progression by regulating immune cells and chondrocytes. This study sets out to identify the hub cuproptosis‐related gene (CRG) associated with the pathogenesis of RA.

Methods

A series of bioinformatic analyses were performed to evaluate the expression score of CRGs and the immune infiltration landscape between RA and normal samples. The hub gene was screened through the correlation analysis of CRGs, and the interaction network between the hub gene and transcription factors (TFs) was constructed. Finally, the hub gene was validated through quantitative real‐time polymerase chain reaction (qRT‐PCR) of patient samples and cell experiments.

Results

Drolipoamide S‐acetyltransferase (DLAT) was screened as the hub gene. Correlation analysis between the hub gene and immune microenvironment demonstrated that DLAT had the highest correlation with T follicular helper cells. Eight pairs of DLAT–TF interaction networks were constructed. Single‐cell sequencing showed that CRGs were highly expressed in RA chondrocytes, and chondrocytes could be classified into three different subsets. qRT‐PCR was used to validate the above results. Dlat knockdown in immortalized human chondrocytes led to significantly improved mitochondrial membrane potentials and reduced levels of intracellular reactive oxygen species (ROS), mitochondrial ROS and apoptosis.

Conclusions

This study rudimentarily demonstrates the correlation between CRGs and immune cell infiltration in RA. The biomarker DLAT may provide comprehensive insights into the pathogenesis and drug targets of RA.
Public finance management architecture in Tajikistan: International reform advice and domestic reform practice
Authors: Khujamkulov Ismoil
Published: June 2023

Debates persist on the effectiveness of externally driven Public Finance Management (PFM) reforms in developing countries, with limited empirical research and field investigations in the Central Asian region. This study collected evidence through Solution and Leader Driven Change (SLDC) and Problem Driven Iterative Adaptation (PDIA) theoretical framework explanations, policy documents review, interview and survey results and Public Expenditure and Financial Accountability (PEFA) framework assessments to find that not all of the World Bank's advice on PFM improvement was adopted in the first phase of reforms in Tajikistan. Blending SLDC and PDIA arguments, the study investigates both positive deviants and reform failures.
An open competition involving thousands of competitors failed to construct useful abstract classifiers for new diagnostic test accuracy systematic reviews
Authors: Kataoka Yuki , Taito Shunsuke , Yamamoto Norio , So Ryuhei , Tsutsumi Yusuke , Anan Keisuke , Banno Masahiro , Tsujimoto Yasushi , Wada Yoshitaka , Sagami Shintaro , Tsujimoto Hiraku , Nihashi Takashi , Takeuchi Motoki , Terasawa Teruhiko , Iguchi Masahiro , Kumasawa Junji , Ichikawa Takumi , Furukawa Ryuki , Yamabe Jun , Furukawa Toshi A.
Published: June 2023

There are currently no abstract classifiers, which can be used for new diagnostic test accuracy (DTA) systematic reviews to select primary DTA study abstracts from database searches. Our goal was to develop machine‐learning‐based abstract classifiers for new DTA systematic reviews through an open competition. We prepared a dataset of abstracts obtained through database searches from 11 reviews in different clinical areas. As the reference standard, we used the abstract lists that required manual full‐text review. We randomly splitted the datasets into a train set, a public test set, and a private test set. Competition participants used the training set to develop classifiers and validated their classifiers using the public test set. The classifiers were refined based on the performance of the public test set. They could submit as many times as they wanted during the competition. Finally, we used the private test set to rank the submitted classifiers. To reduce false exclusions, we used the Fbeta measure with a beta set to seven for evaluating classifiers. After the competition, we conducted the external validation using a dataset from a cardiology DTA review. We received 13,774 submissions from 1429 teams or persons over 4 months. The top‐honored classifier achieved a Fbeta score of 0.4036 and a recall of 0.2352 in the external validation. In conclusion, we were unable to develop an abstract classifier with sufficient recall for immediate application to new DTA systematic reviews. Further studies are needed to update and validate classifiers with datasets from other clinical areas.
Quality of life of older gynecologic oncology patients at the initiation of chemotherapy
Authors: Kleven Anne Grethe , Miaskowski Christine , Torstveit Ann Helen , Ritchie Christine Seel , Engh Marie Ellström , Andersen Elin , Utne Inger
Published: June 2023

Aim

To evaluate older gynecologic oncology patients' quality of life (QOL) at the initiation of chemotherapy and compare their QOL scores with a female age‐matched general population (GP) sample.

Design

Cross‐sectional.

Methods

Older (n = 122) gynecologic oncology patients completed the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (QLQ‐C30) that evaluates global health and five functional scales (range from 0 to 100). Differences in QOL scores between our sample and the GP were evaluated using one‐sample t‐tests and effect sizes were calculated using Cohen's d.

Results

Patients' mean age was 70.7 years (±6.6). Mean scores for the function scales ranged from 58.5 (±31.1) for role function to 86.1 (±17.0) for cognitive function. Compared to the GP, our sample reported significantly lower scores for global health status, social, role and physical functioning, and a significantly higher score for cognitive functioning. No differences were found in emotional functioning scores.

Patient or Public Contribution

No patient or public contribution.
A new high order hybrid WENO scheme for hyperbolic conservation laws
Authors: Li Liang , Wang Zhenming , Zhao Zhong , Zhu Jun
Published: June 2023

This article proposes an improved hybrid weighted essentially non‐oscillatory (WENO) scheme based on the third‐ and fifth‐order finite‐difference modified WENO (MWENO) schemes developed by Zhu et al. in (SIAM J. Sci. Comput. 39 (2017), A1089–A1113.) for solving hyperbolic conservation laws. The MWENO schemes give a guideline on whether to use the WENO scheme or the linear upwind scheme. Unfortunately, because there is no explicit formula for computing the roots of algebraic polynomials of order four or higher, it is difficult to generalize this criterion to higher order cases. Therefore, this article proposes a simple criterion for constructing a series of seventh‐, ninth‐, and higher‐order hybrid WENO schemes, and then designs a class of improved smooth indicator WENO (WENO‐MS) schemes. Compared with the classical WENO schemes, the main advantages of the WENO‐MS schemes are their robustness and efficiency. And these WENO‐MS schemes are more efficient, have better resolution, and can solve many extreme problems without any additional techniques. Furthermore, a simplification criterion is proposed to further improve the computational efficiency of the WENO‐MS schemes, and these simple WENO‐MS schemes are abbreviated as WENO‐SMS schemes in this article. Extensive numerical results demonstrate the good performance of the WENO‐MS schemes and the WENO‐SMS schemes.
Vestibular Tests Related to Tumor Volume in 137 Patients With Small to Medium‐Sized Vestibular Schwannoma
Authors: Nilsen Kathrin Skorpa , Nordahl Stein Helge Glad , Berge Jan Erik , Dhayalan Dhanushan , Goplen Frederik Kragerud
Published: June 2023

Objective

The video head impulse test (vHIT) and cervical and ocular vestibular evoked myogenic potentials (cVEMP and oVEMP) are new methods for measuring peripheral vestibular function. The objectives of this study were to compare these tests and the traditionally used caloric test in patients with small and medium‐sized untreated vestibular schwannoma (VS) and to measure the correlation between the tests' results and tumor volume.

Study Design

National cross‐sectional study.

Setting

Tertiary university clinic.

Methods

Prevalence of abnormal cVEMP, oVEMP, caloric test, and 6‐canal vHIT results on the tumor side and the nontumor side were compared and related to tumor volume with regression analyses in 137 consecutive VS patients assigned to a wait‐and‐scan protocol in the period 2017 to 2019.

Results

The sensitivity of 6‐canal vHIT, caloric test, cVEMP, and oVEMP to detect vestibulopathy in VS patients was 51%, 47%, 39%, and 25%, respectively. Normal tests were found in 21% of the patients. The results of vHIT and caloric test were related to tumor volume, but this was not found for cVEMP and oVEMP.

Conclusion

The caloric test and 6‐canal vHIT showed the highest sensitivity in detecting vestibulopathy in untreated VS patients. vHIT, and particularly the posterior canal, was limited with a high prevalence of abnormal results on the nontumor side. A combination of cVEMP and caloric test was favorable in terms of a relatively high sensitivity and low prevalence of abnormal results on the nontumor side. Larger tumors had a higher rate of pathology on caloric testing and vHIT.