bluuebunny/crossref_metadata_2025 huggingface dataset:
Edukasi Pengobatan Swamedikasi Batuk Flu Pada Anak
Authors: Risma Sakti Pambudi
Published: June 2022

Swamedikasi merupakan upaya yang sering dilakukan oleh seseorang dalam mengobati gejala sakit atau penyakit yang sedang dideritanya sebelum konsultasi kepada dokter. Swamedikasi akan berefek buruk kika terjadi kesalahan dalam mengenali gejala , pemilihan obat, dosis dan keterlambatan dalam mencari informasi. Sehingga hal ini dapat menjadi salah satu faktor terjadinya medication error. Batuk dan Flu seringkali terjadi pada kalangan anak-anak. Orang tua perlu mendapatkan  pemahaman dan pengetahuan terkait swamedikasi batuk dan flu yang dapat dilakukan secara farmakologi dan tradisional. Upaya yang dapat dilakukan adalah dengan memberikan edukasi swamedikasi pada masyarakat. Kegiatan edukasi ini bertujuan untuk meningkatkan edukasi masyarakat sekitar tentang swamedikasi batuk dan pilek pada anak. Metode yang digunakan dalam pengabdian ini adalah melalui edukasi  menggunakan media brosur. Edukasi dilakukan untuk memberikan pengetahuan kepada peserta dan menghindari rasa panik jika anak mengalami batuk dan flu. Respon peserta terhadap pemberian edukasi baik dan hasil menunjukkan bahwa peserta memahami terkait swamedikasi batuk dan flu pada anak (95%).
Pengaruh Profesionalisme, Integritas, Pengalaman Terhadap Pertimbangan Tingkat Materialitas: Tanggung Jawab Auditor Sebagai Pemoderasi
Authors: Krisna Hari Kurnia , Zen Hasan
Published: June 2022

Rumusan masalah dalam penelitian ini adalah bagaimanakah Pengaruh Profesionalisme Auditor, Integritas Auditor, dan Pengalaman Auditor terhadap Pertimbangan Tingkat Materialitas Dalam Pemeriksaan Laporan Keuangan dengan Tanggung Jawab Auditor Sebagai Variabel Pemoderasi (Studi Kasus pada Kantor Akuntan Publik dan Badan Pemeriksa Keuangan Republik Indonesia Perwakilan Sumatera Selatan di Kota Palembang). Jenis penelitian yang digunakan adalah penelitian asosiatif. Data yang digunakan yaitu data primer dan sekunder. Populasi dalam penelitian ini adalah auditor yang tersebar di KAP dan BPK RI Palembang sebanyak 62 responden. Teknik pengumpulan data yaitu dengan menggunakan wawancara, observasi, kuesioner, dan survei. Metode analisis data yang digunakan dalam penelitian ini adalah analisis kualitatif dan analisis kuantitatif. Hasil menunjukkan bahwa profesionalisme auditor dan pengalaman auditor tidak mempengaruhi pertimbangan tingkat materialitas, integritas auditor mempengaruhi pertimbangan tingkat materialitas. Kemudian tanggung jawab auditor memoderasi profesionalisme auditor dan pengalaman auditor secara pure moderator terhadap pertimbangan tingkat materialitas, sementara tanggung jawab auditor memoderasi integritas auditor secara ekuasi moderator terhadap pertimbangan tingkat materialitas.
Inventarisasi Tumbuhan Obat Tradisional Di Wilayah Bendungan Mila Kabupaten Dompu
Authors: Wahyuningsih Daniah , Juhaini Juhaini , Novita Heny , Nurafiatullah Nurafiatullah , Rosninda Rosninda , Awalyah Yonanda , Suryani Suryani , Oktaviana Mia , Ade Ningsih Tri , Azmin Nikman , Nasir Muh
Published: June 2022

Jumlah tumbuhan obat di Indonesia bervariasi, hingga saat ini jumlahnya belum banyak diketahui seacara pasti, sehingga diperlukan pendokumentasian secara menyeluruh untuk pemanfaatan tumbuhan sebagai bahan baku pengobatan. Penelitian  bertujuan  untuk  mengetahui  jenis-jenis  tumbuhan  obat  dan bagian  yang  di  manfaatkan  serta  khashiat  tumbuhan.  Metode  penelitian  yang  digunakan  yaitu kombinasi  teknik  survei  lapangan  (observasi), terhadap masyarakat di wilayah Bendungan Mila Kabupaten Dompu. Populasi dalam penelitian ini adalah seluruh masyarakat wilayah bendungan mila kabupaten dompu. Sampel dalam penelitian ini adalah masyarakat yang memiliki pengetahuan tentang pengobatan tradisional dengan pemanfaatan tumbuhan obat. Analisis data menggunakan analisis deskriptif kualitatif, hasil penelitian  menunjukan bahwa tumbuhan obat tradisional yang dimanfaatkan sebagai obat sebanyak 19 jenis tumbuhan bekhasiat obat yang digunakan dalam pengobatan tradisional
Studi Keanekaragaman Tumbuhan Obat Tradisional Di Wilayah Bendungan Mila Kabupaten Dompu
Authors: Mulisa Mulisa , Hayatun Atun , Rizki Reni , Putri Nanda , Mirnawati Eti , Putri Zahra Nurul , Natalia Nafa , Apriati Mira , Mahdalena Serlin , Haryati Haryati , Azmin Nikman , Nurlailah Nurlailah
Published: June 2022

Penelitian ini bertujuan untuk mempelajari tumbuhan obat di Kawasan Bendungan Mila Kabupaten Dompu. Metode yang digunakan adalah survey lapangan dan wawancara. Penelitian ini berguna untuk mengetahuai jenis tumbuhan apa saja yang dimanfaatkan sebaagai obat-obatan tradisoanal. Hasil penelitian ini menunjukkan bahwa ada 15 jenis tumbuhan obat tradisonal yang digunakan dan dimanfaatkan oleh masyarakat. Bagian tumbuhan obat tradisoanal biasa digunakan masyarakat sebagai obat yaitu daun, batang, kulit, buah, biji, umbi, kayu, dan akar.  Adapun cara pengolahan tumbuhan obat tradisional yaitu dengan cara direbus, ditempel, digosok, ditumbuk, dan di konsumsi secara langsung.
Karakteristik Fisik Dan Mutu Organoleptik Kopi Bumi Pajo Pada Berbagai Metode Fermentasi
Authors: Hartati Hartati , Azmin Nikman , Irwansyah Muhammad
Published: June 2022

Kopi merupakan salah satu komoditas pertanian yang memiliki nilai ekonomi yang sangat tinggi. Biji Kopi umumnya diolah dengan beberapa cara pengolahan yaitu cara basah dan cara kering, salah satu tahapan pengolahan cara basah pada biji kopi yang sangat menentukan mutu adalah dengan metode fermentasi. Fermentasi bertujuan untuk menghilangkan lapisan lendir yang tersisa dipermukaan kulit biji kopi setelah proses pembersihan. Tujauan penelitian ini adalah untuk mengetahui karakteristik fisik bubuk kopi dan mutu organoleptik bubuk kopi pada berbagai metode fermentasi. Penelitian ini dilakukan di Laboratorium Biologi STKIP Bima, sampel biji kopi di ambil di Kecamatan Bumi Pajo Desa Rora Kecamatan Donggo Kabupaten Bima. Waktu penelitian dilakukan selama 4 bulan. Indicator yang diamati dalam penelitian ini adalah kadar air bubuk kopi, warna, cita rasa, aroma, kepahitan, dan kesukaan. Dari hasil uji organoleptik terhadap mutu kopi, menunjukkan berpengaruh nyata terhadap warna, rasa dan aroma seduhan bubuk kopi, tetapi perpengaruh tidak nyata terhadap kepahitan dan tingkat kesukaan. Panelis lebih menyukai seduhan bubuk kopi pada perlakuan fermentasi kering dengan lama fermentasi 6 dan 8 hari
Pengaruh Jarak Tanam Dan Dosis Pupuk Kandang Terhadap Pertumbuhan Tanaman Cabai Rawit (Capsicum frutescens)
Authors: Erni Suryani
Published: June 2022

Penelitian ini bertujuan untuk mengetahui pengaruh jarak tanam dan dosis pupuk kandang terhadap pertumbuhan cabai rawit, serta interaksi kedua faktor tersebut. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) dengan 2 faktor. Faktor pertama: spasi (J) terdiri dari 3 level. faktor kedua adalah dosis pupuk kandang yang terdiri dari 4 taraf dengan 3 kali ulangan. Parameter yang diamati adalah Tinggi Tanaman, Jumlah Daun, Jumlah Cabang dan diukur dari umur 7, 21 dan 35 HST. Hasil penelitian yang telah dilakukan, bahwa jarak tanam berpengaruh sangat nyata terhadap tinggi tanaman cabai rawit pada perlakuan J2 pada 35 HST dan jumlah cabang pada perlakuan J2 pada 7 HST, dan tidak berpengaruh nyata. berpengaruh terhadap jumlah daun pada umur 7 HST, 21 HST, dan 35 HST. Pada aplikasi pupuk kandang, rata-rata tinggi tanaman cabai rawit tidak terlalu berbeda, kecuali pada perlakuan P3 pada 35 HST. Namun secara keseluruhan pada perlakuan P0 sampai P3 umur tanam 35 HST pertumbuhan tanaman cabai rawit sangat baik. Pada perlakuan P3 pada 35 HST rata-rata tinggi cabai rawit 34,78 cm. Pertumbuhan cabai rawit pada perlakuan ini sangat baik, sehingga dapat disimpulkan bahwa pemberian pupuk kandang 1,5 kg dengan jarak tanam 50 cm x 60 cm sangat berpengaruh terhadap pertumbuhan tanaman cabai rawit. Rata-rata jumlah daun cabai rawit tidak berpengaruh nyata berdasarkan jumlah aplikasi pupuk kandang, hal ini terlihat dari data perlakuan P0 sampai P3 pada umur 7 HST sampai 35 HST menunjukkan angka yang hampir sama. Jarak tanam tanaman cabai rawit juga mempengaruhi jumlah cabang. Data menunjukkan cabang daun paling banyak terdapat pada perlakuan J2 dengan jumlah rata-rata tertinggi 6,00 dan 5,17 helai.
ASSESSMENT OF THE IMPACT OF COVID-19 ON GST COLLECTION IN INDIA
Authors: Bhura Pawan Kumar , Jha Ashutosh Kumar
Published: June 2022

With the origin of COVID-19 in December, 2019 from China, the novel corona virus gradually reached all the countries of the world and has caused severe loss of human lives and damage to the economy of the country. The global economy has been shattered during this pandemic time. India is no exception and various sectors of Indian economy have witnessed severe pandemic consequences. Virus has affected GDP, employment, tax collections and various other aspects of Indian economy. GST which is a combined format of various indirect taxes in India is a significant indicator of economic activities important for the economy of the nation. The present study has been designed to analyze the impact of corona pandemic on GST collections during the period between January 2018 and December 2021, which is a pivotal marker for assessment of the economy.
Elżbieta Chojnacka jako krytyk wykonawstwa historycznego
Authors: Gajecka-Antosiewicz Aleksandra
Published: June 2022

Artykuł prezentuje poglądy Elżbiety Chojnackiej na temat interpretacji muzyki dawnej na tle tendencji historyzujących, pionierskich wydań utworów klawesynowych, a także sztuki wykonawczej Wandy Landowskiej. Kompilacja wypowiedzi artystki zaczerpnięta z licznych wywiadów obrazuje jej walkę z „terroryzmem estetycznym” w nurcie „Historically informed performance” - krytycznego stanowiska jakie zajęła Chojnacka wobec praktyki wykonywania dawnej muzyki wyłącznie na kopiach instrumentów historycznych.
Solutions to Minimize Sediment Resuspension in Ports
Authors: Srše Jure , Perkovič Marko , Androjna Andrej , Brcko Tanja
Published: June 2022

Sediment resuspension has, among other things, negative consequences for marine flora and fauna. A solution to this problem could lie in alternative ship manoeuvres, automated mooring systems and bottom protection techniques. The paper deals with the methodology for determining sediment resuspen-sion, which consists of real-time kinematic measurements and in-situ meas-urements with (PNS-RTK) sensors. Real-time data from the manoeuvring vessel is used to determine the critical vessel rate per minute (RPM) or pro-peller jet velocity on the seabed and to identify the most common critical ves-sel manoeuvres on approach to port and departure. The Full Mission Bridge Simulator (FMBS) can be an excellent simulation tool for the analysis of real-time and on-site measurements, which is proposed for further research.
A Discourse Analysis Approach to Email Communication on Ships
Authors: Dževerdanović-Pejović Milena
Published: June 2022

Emails have become an inevitable communication tool in a specific profes-sional environment such as a ship. Changes that arose due to data digitaliza-tion, automatization and advances in communication systems have expanded the scope of internal and external ship business correspondence. Neverthe-less, the structure of an email as a genre in seafaring has adapted to generic schemata in online communication and ship-specific communicative stand-ards. Based on the genre analysis theories put forward by Swales and Bhatia, we analyse a corpus of emails collected from five foreign companies (100 pages of text). Then, the collected data were explained and interpreted con-cerning the contextual setting, primarily participants and their role in the giv-en shipboard situation. The findings of this paper have pedagogical implica-tions for creating teaching material for present and future ESP courses and introducing the concept of genre in establishing communication patterns in email correspondence on ships.
An Analysis of Qualifications and Personal Characteristics of Successful Marina Manager
Authors: Šekularac Ivošević Senka , Milošević Dragana
Published: June 2022

As a modern industry based on meeting the high-demanding customers who prefer vacation and recreation at sea, nautical tourism requires professional staff with renowned qualifications and personalities developed. Marina managers especially should reach this imperative of industry mentioned. The methodology in this paper is inherent in the methodology of social sciences. The primary research includes surveys and in-depth interviews examining the attitudes of marina managers in Montenegro about professional requirements and personal attributes that describe successful careers. The research results confirm previous findings in the literature and shape the position of marina managers based on the necessary education, experience, technical and leadership skills, and personalities. Implications of this paper refer to improving study plans and programs in maritime education, which is the first step in developing high-quality management staff in the marina business.
MASS Level III – Exploration of Current Issues from an Operational Point of View
Authors: Mišković Darijo
Published: June 2022

Despite all efforts to ensure the safety of ships, available statistics show that the human factor remains the biggest problem in the maritime industry. The desire to improve the safety of ships and the related protection of the environment has been at the heart of the Maritime Autonomous Surface Ships (MASS) concept, which is supported by the International Maritime Organisation (IMO). Although the concept itself seems feasible in principle, there are still a number of open questions from an operational point of view. Furthermore, the economic feasibility of the concept is unknown. This paper ad-dresses questions to which there are currently no answers.
PACKAGING SUPPLIER SELECTION MODEL BASED ON THE ANALYTICAL HIERARCHY PROCESS (AHP) METHOD OF A PHARMACEUTICAL COMPANY
Authors: Prawiro Ardi
Published: June 2022

Analytical Hierarchy Process
ANALYSIS OF COMPANY FINANCIAL PERFORMANCE USING DU PONT SYSTEM METHOD AT PT. ANEKA TAMBANG (PERSERO) DURING THE PANDEMIC AND BEFORE THE COVID-19 PANDEMIC
Authors: Helmalia Hardiyantia
Published: June 2022

Du Pont System
Valvular Prostheses Dysfunction
Authors: Montero Graniela Alfredo
Published: June 2022

Prosthetic heart valve dysfunction can provoke the appearance of symptoms or signs or completely asymptomatic being. A typical symptom of malfunction of the heart valves is the heart failure, with one of its more common symptoms the dyspnea. The substitution of the heart valves with mechanical or biological prosthesis can cause a heart dysfunction. There was carried out a review with the objective to describe the main causes and the handling of the prosthetic heart valve dysfunction. In patient with valve substitution can appear failure, either for intrinsic or extrinsic dysfunction, being these last ones those of more incidence. The handling from the clinical point of view and the medical treatment precocious is fundamental pillars to elevate the patients' quality life. The surgery is generally reserved to patient with recurrence or severe complications
Nutrition Section Position Statement and Clinical Practice Recommendations for Children Admitted to Intensive Care Unit
Authors: Rohani Pejman , Alimadadi Hosein , Mirrahimi Bahador , Yaghmaie Bahareh , Hashemi Seyedeh Masumeh , Ahmadizadeh Seyedeh Narjes , Olang Beheshte , Hashemian Seyed Mohammadreza , Jamaati Hamidreza , Ashtijoo Parastoo , Hasanzad Maryam , Behzad Azita , Sayyari Aliakbar
Published: June 2022

Context: Children admitted to the intensive care unit are at risk of malnutrition, mainly due to chronic diseases they are suffering from. These patients require a different nutritional diet regimen from those in a normal or stable disease state due to change in metabolism under the stress of diseases. Methods: According to the SIGN guideline based on evidence, first, articles matching our criteria were extracted from the literature, and then the strength of evidence was evaluated. Finally, a summary of statements consisting of details regarding the strength of evidence and recommendation level was reviewed by 12 experts, and two-round surveys were accomplished according to the Delphi method to reach a consensus. Results: Twenty-seven statements in 5 categories with strength of evidence, grade of recommendations, and expert opinions are summarized. Conclusions: Rapid nutritional assessment, judging patients with malnutrition or at risk of malnutrition, fast intervention with early enteral nutrition, reaching the protein and energy goals under the supervision of an expert registered dietitian, and persistent monitoring with minimizing the time of fasting are some of the key components of proper nutrition management based on evidence found in the literature.
En defensa del procesamiento del lenguaje natural fundamentado en la lingüística teórica
Authors:   Departamento de Lingüística Aplicada, Universidad Politécnica de Valencia (España), Periñán Pascual Carlos
Published: June 2022

A pesar de que podríamos ubicar el procesamiento del lenguaje natural entre la lingüística aplicada y la inteligencia artificial, el papel que ha desempeñado la lingüística teórica a lo largo de la historia de esta disciplina ha sido generalmente poco notorio. uno de los objetivos de este artículo es desgranar las causas de esta malograda simbiosis entre las investigaciones de lingüistas e informáticos, donde los enfoques probabilísticos han ido gradualmente relegando los modelos lingüísticos a un segundo plano, en el mejor de los casos. A pesar de este desalentador panorama, FunGramKB, una base de conocimiento particularmente útil para sistemas que requieran la comprensión del lenguaje, sirve para ilustrar cómo actualmente la lingüística teórica y la ciencia cognitiva pueden contribuir al desarrollo de un proyecto de ingeniería del conocimiento.
Fundamentos metodológicos de la creación subontológica en FunGramKB
Authors:   Departamento de Filologías Inglesa y Alemana, Facultad de Ciencias Económicas y Empresariales, Universidad de Granada (España), Felices Lago Ángel , Ureña Gómez-Moreno Pedro ,   Departamento de Filologías Inglesa y Alemana, Facultad de Ciencias Económicas y Empresariales, Universidad de Granada (España)
Published: June 2022

ste artículo describe las bases metodológicas para la construcción de subontologías terminológicas en la base de conocimiento FunGramKB y se parte de la hipótesis de que el modelo multinivel de la Ontología nuclear (nivel metaconceptual, nivel básico y nivel terminal) puede conectarse a una subontología con el fin de minimizar la redundancia informativa y maximizar el conocimiento. en el marco de FunGramKB, las subontologías se caracterizan, en primer lugar, por contener conceptos pertenecientes a dominios de conocimiento especializado y, en segundo lugar, por orientar esos conceptos a la semántica profunda –a diferencia del enfoque de la gran mayoría de las ontologías terminológicas, que suelen orientarse a la semántica superficial. el desarrollo de las subontologías permitirá la aplicación futura de FunGramKB a tareas de procesamiento de lenguaje especializado y razonamiento experto.
The semantic development of IE *weid- to the meaning ‘know’ and the possible contrast with IE *gneh3
Authors:   Department of Greek and Latin, University College London (Reino Unido), Silva Trinidad
Published: June 2022

No presenta resumen en español
When pain is not a place: Pain and its metaphors in late middle English medical texts
Authors:   Departamento de Filología Moderna, Facultad de Letras, Universidad de Castilla-La Mancha (España), Díaz Vera Javier E.
Published: June 2022

In this research i will identify and describe the metaphorical expressions for pain recorded in the texts included in the Middle English Medical Texts corpus, a collection of english medical writings from the period 1350- 1500. Furthermore, i will propose a comparison between the resulting list of specialised medical metaphors and a list of metaphorical patterns for pain extracted from a multi-genre, late middle english corpus, the Helsinki Corpus of English Texts (subperiods me iii and me iV), which i will use here as my reference corpus. in doing so, i will try to show that medieval medical authors borrowed or developed new metaphorical extensions in order to describe pain and its treatments. Through the use of these metaphorical patterns, medieval medical writers tried to refer to pain as a process, with a beginning, a treatment and an end. in fact, pain is frequently conceived of as a living entity of adverse nature (e.g. a soldier, an enemy, a wild animal), and it is the doctor’s role to fight it with all the weapons (i.e. treatments) at his disposal. These conceptual choices differ greatly from the conceptualizations of pain found in the multi-genre corpus, where pain is frequently conceived of as a permanent state or as a place.
¿Qué hay en un eik'óse (cuento) kawésqar? Perdido en la traducción1
Authors:   Fundación para el Desarrollo de la Duodécima Región (FIDE XII) (Chile), Aguilera Óscar
Published: June 2022

En este artículo se examinan algunos rasgos característicos de los cuentos kawésqar, aspecto desconocido a la fecha de la literatura oral de uno de los pueblos fueguinos más antiguos de Chile; asimismo se analizan en general algunos problemas de la traducción de este tipo de literatura oral y, en particular, los que se han encontrado en la traducción de estos textos kawésqar
Cross-linguistic investigation of Greek and Latin prefixes: Spanish and English contrastively
Authors:   Universidad Politécnica de Valencia (España), Montero-Fleta Begoña
Published: June 2022

This manuscript sets forth an in-depth study of competing pairs of prefixes of Greek and Latin origin: hyper- vs. super-, micro- vs. mini-, and polyvs. multi- from a contrastive Spanish-English perspective. Two major source corpora, the Corpus de Referencia del Español Actual for Spanish, and the British National Corpus for English were used for the purpose of this research. The prefixes were further analysed within the framework of a corpus of 200 translational equivalences, compiled from a lexicographic bilingual source, the Oxford Spanish Dictionary (2003); the results were then corroborated with the use of the prefixed words in a bilingual text-based online source, Linguee. This research sheds light on similarities and differences between such pairs of prefixes. The present contribution confirms the higher use of prefixation in Spanish. A much more frequent use of Latin prefixes, mainly super- and multi-, is attested in both languages. The cross-linguistic study reveals that prefixes seem to overlap semantically and syntactically across Spanish and English. Nevertheless, a representative percentage of Spanish prefixed words contrastively exhibit a non-morphological equivalence in English. Hence, a single different word, or a multiword unit may be used in English where derivational expansion of the base is preferred in Spanish
Ofelia García: Bilingual Education in the 21st Century: A Global Perspective
Authors:   University of Washington (Estados Unidos), Becerra Lubies Rukmini
Published: June 2022

Sin Resumen
Milagros Aleza Izquierdo y José María Enguita Utrilla: La lengua española en América: normas y usos actuales
Authors:   Universidad de Oviedo (España), García Rodríguez Alba , Bleortu Cristina ,   Universidad de Oviedo (España)
Published: June 2022

Sin Resumen
A Prospective Observational Study on Prescribing Pattern and Outcome of Acute Stroke from a Tertiary Care Hospital in Bengaluru, India
Authors: Dey Gargi , Jyothi R , Pradeep C , Girish K
Published: June 2022

Introduction: Stroke is the most common cerebrovascular disorder and a second leading cause for death. Early diagnosis and treatment of stroke along with controlling of risk factors, post stroke infection and rehabilitation can enhance patient outcomes. Stroke is an important economic burden for the society, requiring increasing attention for more effective healthcare planning and resources allocation. Aim: To determine the prescribing pattern, risk factors and outcome of acute stroke in a tertiary care hospital. Materials and Methods: A prospective observational study was conducted in the Department of Medicine, at Kempegowda Institute of Medical Sciences Hospital and Research Centre, Bangalore, Karnataka, India, from January 2018-June 2019 for 18 months. After approval and clearance obtained from the Institutional Ethics Committee, 100 acute stroke subjects of either gender with or without co-morbidities were included in the study. Relevant information about the ongoing drug therapy, co-morbidities, personal and past history were obtained. The outcome of the stroke was assessed by Modified Rankin Scale (mRS). Chi-square test was used for categorical data, student t-test for continuous data and Analysis of Variance (ANOVA) test for temporal change in mean mRS. Results: The mean age of the subjects in the study was 68.41±12.98 years. Ischaemic stroke (72%) was more common than haemorrhagic stroke (28%). Hypertension and diabetes were significantly associated with stroke with p-value of 0.04 and 0.02 respectively. Association of smoking and alcohol with stroke was significant with p-value of 0.01 and 0.001 respectively. The most commonly prescribed drugs were aspirin, clopidogrel and statins. The mean mRS at admission for both ischaemic and haemorrhagic stroke came down after 28 days with treatment and rehabilitation. At the end of 28th day Ischaemic Stroke showed better outcome than haemorrhagic stroke (p-value: 0.03). Conclusion: Early diagnosis, lifestyle changes and combination drug therapy reduce complication of stroke and improve patients’ outcome. Risk factors such as hypertension, diabetes mellitus, smoking and alcohol should be controlled. Antiplatelet agents, antihypertensive agents and statins are commonly prescribed for secondary prevention and treatment of stroke. Greater awareness is needed to reduce the burden of stroke
Comparing the Effectiveness of Ambu® AuraGain™ Laryngeal Mask Airway with LMA® ProSeal™ in Patients Undergoing Laparoscopic Surgeries- A Randomised Clinical Trial
Authors: Manisha MK , Bharadwaj Archana Anilkumar , Kamath Shyamsunder
Published: June 2022

Introduction: Second generation Supraglottic Airway Devices (SADs) contain a gastric drain tube which separates the respiratory and the alimentary tract. This provides a better oropharyngeal seal and reduces the risk of pulmonary aspiration of refluxed gastric contents compared to the first generation SADs. Aim: To compare Ambu® AuraGain™ (AAU) laryngeal mask airway with LMA® ProSeal ™ (PLMA) in terms of Oropharyngeal Leak Pressure (OLP) in laparoscopic surgeries. Materials and methods: This randomised clinical study was conducted from December 2017 to September 2019, at Shri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital, Dharwad, India in 80 patients, aged 18 to 65 years, of American Society of Anesthesiologists (ASA) physical status I and II undergoing laparoscopic surgeries. Patients were randomly assigned to one of the two groups: group PLMA and group AAU. After induction of anaesthesia, SADs were inserted by an experienced anaesthesiologist. OLP, pharyngeal mucosal pressure, peak airway pressure and secondary outcome parameters (the number of attempts, time required, ease, and hemodynamic response associated with insertion of LMA) were recorded at set time points. Data was analysed using Statistical Packages for Social Sciences (SPSS) version 22. Results: All patients in both the groups were comparable in terms of demographic data and baseline vital parameters. The Oropharyngeal Leak Pressure of group AAU was comparable to group PLMA at all measured time-points. The two groups were comparable in terms of pharyngeal mucosal pressure immediately after insertion of LMA, but group AAU had lesser pharyngeal mucosal pressure compared to group PLMA immediately after pneumoperitoneum, at 30 and 60 minutes. Mean peak airway pressures were lower in group AAU than group PLMA immediately after insertion of LMA (15.53±1.50 versus 17.06±2.56 cmH2 O, p=0.004) and immediately after creation of pneumoperitoneum (23.03±2.96 versus 23.03±2.96 cmH2 O, p= 0.04). Both the groups were comparable in terms of number of attempts, time taken, haemodynamic response associated with LMA insertion and with passage of gastric tube except that PLMA was easier to insert in the first attempt compared to AAU (26/40 versus 13/40, Grade 1 ease of insertion). Conclusion: Ambu® AuraGain™ could be a useful alternative to LMA® ProSeal ™ in patients undergoing laparoscopic surgeries.
Study of Serum Level of Interleukin 33 in Systemic Lupus Erythematosus Patients
Authors: Saqr Rana Gamal , Elsharaby Radwa Mahmoud , Shahba Abeer Abdelmenem , Hazzaa Sahar Mohey Eldin
Published: June 2022

Background: Systemic lupus erythematosus (SLE) is a chronic disease in which the immune system of the body attacks body tissues in multiple body systems, so it is called autoimmune disease. Arthritis, skin rash, photosensitivity, and nephritis are the most common clinical presentation in SLE. Interleukin 33 (IL-33) is one of the interleukins family, and it is established that IL-33 is central in inborn and acquired immunity. Historically, the IL-33 receptor was discovered first on the surface of T helper 2 cells and not T helper T1 cells.

Aim: Measuring Interleukin-33 level in serum of SLE patients and its relation to clinical presentation, activity, and severity of the disease.

Subjects and Methods: This study was conducted at Clinical Pathology and Internal Medicine Departments-Tanta University Hospital from March 2019 to December 2019 on 80 subjects

Results: The affected females were at the childbearing period, and the incidence among gender is higher for females than that for males, which reflects the hormonal role in SLE development. Serum creatinine, blood urea nitrogen, ESR levels were increased significantly in SLE patients than in the control group. There was a significant increase in serum IL-33 levels in SLE patients than control group indicating that IL-33 has a role in the pathogenesis of SLE. There was a significant difference in Hb, platelet count, ANA, and anti-ds-DNA between SLE patients and the control group. There was a significant positive correlation between IL-33 and serum creatinine, ESR, CRP, and SLEDAI. The most common feature was arthritis (88.3%) of patients, followed by skin rash (60.0%) of patients.

Conclusion: IL-33 levels in patients with SLE were significantly higher than that in the control group, and its level was significantly related to disease activity. This indicated that IL-33 has a role in the pathogenesis of SLE. So, IL-33 can be used as a diagnostic and a prognostic marker.
Formação da rede de capital social no território citrícola de Alagoas
Authors: Gonçalves Kellyane Pereira dos Anjos , Rosário Francisco José Peixoto , Paulillo Luiz Fernando de Oriani
Published: June 2022

Este artigo utilizou o referencial teórico do neo-institucionalismo para analisar o papel do Estado na formação da rede citrícola de Alagoas. O objetivo principal foi analisar o processo de formação da rede de capital social na região conhecida como Vale do Mundaú. Para isso, a metodologia constituiu-se de um estudo de campo baseado em pesquisa documental e nos métodos observacional e de entrevista a atores chave da rede. Os resultados mostraram que apesar da rede ter começado a se formar em 2002 com o projeto Vida Rural Sustentável e com a constituição da primeira cooperativa, foi a partir de 2008 com a inserção do território no programa de estado PAPL que se desenvolveu um conjunto de características responsáveis pela articulação sistemática dos atores. Com isso, concluiu-se que o Estado é um ator fundamental para o desenvolvimento do capital social quando este promove um ambiente de interação e participação dos demais atores na formulação das políticas de desenvolvimento local.
O programa agentes locais de inovação e seus impactos nas patentes dos pequenos negócios no Distrito Federal
Authors: Mendes Dany Rafael Fonseca , Gomes Ricardo Robson Moreira , Aragão Joao Carlos Medeiros de , Cunha George Henrique de Moura
Published: June 2022

Este trabalho tem por objetivo apresentar os resultados das ações do programa agentes locais de inovação e os seus possíveis impactos no volume de depósitos de patentes, em uma perspectiva para as atividades econômicas de pequena dimensão localizadas no Distrito Federal. A realização desta pesquisa contou uma amostra de aproximadamente 18% do universo de quase cinco mil estabelecimentos comerciais de micro e pequenas empresas.
Assessment of burden and segregation profiles of CNVs in patients with epilepsy
Authors: Moreau Claudia , Tremblay Frédérique , Wolking Stefan , Girard Alexandre , Laprise Catherine , Hamdan Fadi F. , Michaud Jacques L. , Minassian Berge A. , Cossette Patrick , Girard Simon L.
Published: June 2022

Objective

Microdeletions are associated with different forms of epilepsy but show incomplete penetrance, which is not well understood. We aimed to assess whether unmasked variants or double CNVs could explain incomplete penetrance.

Methods

We analyzed copy number variants (CNVs) in 603 patients with four different subgroups of epilepsy and 945 controls. CNVs were called from genotypes and validated on whole‐genome (WGS) or whole‐exome sequences (WES). CNV burden difference between patients and controls was obtained by fitting a logistic regression. CNV burden was assessed for small and large (>1 Mb) deletions and duplications and for deletions overlapping different gene sets.

Results

Large deletions were enriched in genetic generalized epilepsies (GGE) compared to controls. We also found enrichment of deletions in epilepsy genes and hotspots for GGE. We did not find truncating or functional variants that could have been unmasked by the deletions. We observed a double CNV hit in two patients. One patient also carried a de novo deletion in the 22q11.2 hotspot.

Interpretation

We could corroborate previous findings of an enrichment of large microdeletions and deletions in epilepsy genes in GGE. We could also replicate that microdeletions show incomplete penetrance. However, we could not validate the hypothesis of unmasked variants nor the hypothesis of double CNVs to explain the incomplete penetrance. We found a de novo CNV on 22q11.2 that could be of interest. We also observed GGE families carrying a deletion on 15q13.3 hotspot that could be investigated in the Quebec founder population.
Inkjet‐Printed Xerogel Scaffolds Enabled Room‐Temperature Fabrication of High‐Quality Metal Electrodes for Flexible Electronics
Authors: Wang Shuaichen , Gao Yuan , Huang Qiyao , Guo Xuyun , Yang Anneng , Zhang Yaokang , Zhuang Qiuna , Chen Dongdong , Chen Lina , Ju Xin , Hu Hong , Zhang Shengdong , Zhu Ye , Yan Feng , Zheng Zijian
Published: June 2022

Inkjet‐printed metal electrodes with desirable morphologies and electrical properties are indispensable cornerstones for printable and flexible electronics. However, methods to fabricate metal electrodes nowadays mostly request the sintering of printed metal particles, which not only will easily damage heat‐sensitive plastic substrates, but also is difficult to achieve a smooth, neat, and highly adhesive electrode structure. Herein, a room‐temperature, solution‐processable copper (Cu) electrode is demonstrated to overcome the above issues. The key is to inkjet print a stable xerogel scaffold with high porosity, good uniformity, and smoothness for growing high‐quality Cu via electroless deposition. Xerogel‐based Cu electrodes exhibit a bi‐layer architecture, consisting of an upper thin‐film Cu (with an electrical conductivity of ≈1.2 × 107 S m−1) and a bottom Cu‐polymer interpenetrated network. The electrodes show an excellent uniformity, surface smoothness, high interfacial energy to the plastic substrates (690–970 mJ m−2), and good flexibility. Taking these merits, the electrodes can be patterned onto various plastic substrates and fabricate all‐solution‐processed electronic devices such as organic thin‐film transistors and organic electrochemical transistors with stable electrical performance.
27.6% Perovskite/c‐Si Tandem Solar Cells Using Industrial Fabricated TOPCon Device
Authors: Wu Yiliang , Zheng Peiting , Peng Jun , Xu Menglei , Chen Yihua , Surve Sachin , Lu Teng , Bui Anh Dinh , Li Nengxu , Liang Wensheng , Duan Leiping , Li Bairu , Shen Heping , Duong The , Yang Jie , Zhang Xinyu , Liu Yun , Jin Hao , Chen Qi , White Thomas , Catchpole Kylie , Zhou Huanping , Weber Klaus
Published: June 2022

The tandem cell structure is the most promising solution for the next generation photovoltaic technology to overcome the single‐junction Shockley–Queisser limit. The fabrication of a perovskite/c‐Si monolithic tandem device has not yet been demonstrated on a c‐Si bottom cell produced from an industrial production line. Here, a c‐Si cell with a tunneling oxide passivating contact (TOPCon) structure produced on a production line as the bottom cell of a tandem device, and a top cell featuring solution‐processed perovskite films to form the tandem device are used. The c‐Si cell features a rough damage etched, but untextured front surface from the wafering processes. To combat the challenge of rough surfaces, several strategies to avoid shunt paths across carrier transport layers, absorber layers, and their interfaces are implemented. Moreover, the origin of reflection loss on this planar structure is investigated and the reflection loss is managed to below 4 mA cm−2. In addition, the source of the voltage loss from the TOPCon bottom cell is identified and the device structure is redesigned to be suitable for tandem applications while still using mass production feasible fabrication methods. Overall, 27.6% efficiency is achieved for a monolithic perovskite/c‐Si tandem device, with significant potential for future improvements.
Ink Engineering in Blade‐Coating Large‐Area Perovskite Solar Cells
Authors: Yang Jinxin , Lim Eng Liang , Tan Li , Wei Zhanhua
Published: June 2022

To date, organic–inorganic hybrid perovskite solar cells (PSCs) have reached a certified efficiency of 25.7%, showing great potential in upscale industrial commercialization. However, a huge obstacle facing the industrialization of PSCs is the decreased efficiency and long‐term stability when upscaling the device area. To overcome these issues, blade‐coating methods have been developed to fabricate large‐area PSCs due to their capability to deposit uniform large‐area perovskite films. Ink engineering plays an important role in the blade‐coating, especially for crystallinity and defect control. In this review, the blade‐coating method to fabricate large‐area perovskite films is first introduced. Then, the perovskite ink engineering for blade‐coating PSCs is systematically summarized. Specifically, the effects of perovskite composition management and solvent engineering on perovskite film quality are discussed, and recent efforts in additive strategy to passivate perovskite defects are also summarized. Subsequently, recent advances in functional layer ink engineering and fully blade‐coated PSCs are summarized. Moreover, the applications of blade‐coating method in hole transporting material‐free carbon‐based PSCs are discussed. Finally, some suggestions and an outlook on this field are provided to help facilitate highly efficient and stable blade‐coated PSCs.
Chemically Tuning Attractive and Repulsive Interactions between Solubilizing Oil Droplets
Authors: Wentworth Ciera M. , Castonguay Alexander C. , Moerman Pepijn G. , Meredith Caleb H. , Balaj Rebecca V. , Cheon Seong Ik , Zarzar Lauren D.
Published: June 2022

Micellar solubilization is a transport process occurring in surfactant‐stabilized emulsions that can lead to Marangoni flow and droplet motility. Active droplets exhibit self‐propulsion and pairwise repulsion due to solubilization processes and/or solubilization products raising the droplet's interfacial tension. Here, we report emulsions with the opposite behavior, wherein solubilization decreases the interfacial tension and causes droplets to attract. We characterize the influence of oil chemical structure, nonionic surfactant structure, and surfactant concentration on the interfacial tensions and Marangoni flows of solubilizing oil‐in‐water drops. Three regimes corresponding to droplet “attraction”, “repulsion” or “inactivity” are identified. We believe these studies contribute to a fundamental understanding of solubilization processes in emulsions and provide guidance as to how chemical parameters can influence the dynamics and chemotactic interactions between active droplets.
Miscibility and rigid amorphous phase in blends of polypropylene with poly(propylene‐co‐ethylene)
Authors: Darweesh Mohamed H. , El‐Taweel Safaa H. , Stoll Bernhard
Published: June 2022

Thermal and mechanical properties of binary blends of polypropylene (PP) with a statistical copolymer (85 wt% propylene and 15 wt% ethylene, abbreviated here as VM) have been investigated. Both components were found to be miscible in the melt in the whole range of compositions. No separate domains of VM have been detected by polarizing optical microscopy, and the size of spherulites is going down with increasing VM content. The crystallization temperature of PP as detected by DSC, is going down to 83°C, for PP/VM blends 10:90. This is another evidence for miscibility in the melt. Viscoelastic properties of the melt were measured. Regarding the solid state, the melting enthalpy is exactly proportional to the PP content in the blend. The DSC step height at the glass transition is exactly proportional to the VM content. These results are suggesting a three‐phase model (crystalline, rigid amorphous, and mobile amorphous phase), where the VM component is mainly located in the mobile amorphous regions, while the amorphous part of PP is in the rigid amorphous regions. Stress–strain curves show a systematic increase of elongation at break with increasing VM%, to be extended from 7.8% to more than 550%.
A new subseasonal atmospheric teleconnection bridging tropical deep convection over the western North Pacific and Antarctic weather
Authors: Sun Yuexiang , Tan Benkui
Published: June 2022

Previous studies indicate that convective heating variability of the western North Pacific summer monsoon (WNPSM) influences strongly weather and climate over East Asia. Based on daily reanalysis data and interpolated outgoing longwave radiation (OLR) data, this study demonstrates that the WNPSM convection can also cause severe weather events remotely over the Antarctic through the exciting of the Australia‐South Pacific‐Atlantic wave train (ASPA pattern). Surface air temperature (SAT) rises over the Ross Sea‐Mawson‐Dumont d'Urville Seas sector and over the Weddell Sea, while the SAT drops over the Amundsen–Bellingshausen Seas. Concurrently, sea ice concentration (SIC) is reduced over the Ross Sea and enhanced over the Amundsen–Bellingshausen Seas. The result suggests that the newly found ASPA pattern may serve as an important bridge linking the WNPSM convection and the weather over the Antarctic region.

The dynamics of ASPA's formation and propagation are also investigated comprehensively. Day‐to‐day energy budget analysis suggests that after its initiation by WNPSM convection, the ASPA pattern is driven by the baroclinic energy conversion from the climatological flow and nonlinear term. The barotropic energy conversion from the climatological flow contributes to positive KE tendency before day +1 and negative KE tendency after day +1. It is therefore extremely important to improve the representations of the climatological‐mean sea ice and jet stream, wave‐mean flow interaction and wave‐wave interaction in the mid‐ and high‐latitudes of the Southern Hemisphere, as well as the convection over the WNPSM region of the Northern Hemisphere in numerical model for a better weather prediction for the Antarctic.
Nonlinear age effects in tactile processing from early childhood to adulthood
Authors: Kaur Sakshi , Espenhahn Svenja , Bell Tiffany , Godfrey Kate J. , Nwaroh Chidera , Giuffre Adrianna , Cole Lauran , Beltrano Winnica , Yan Tingting , Stokoe Mehak , Haynes Logan , Hou Tasha Yuntao , Tommerdahl Mark , Bray Signe , Harris Ashley D.
Published: June 2022

Background

Tactile processing plays a pivotal role in the early stages of human development; however, little is known about tactile function in young children. An understanding of how tactile processing changes with age from early childhood to adulthood is fundamental in understanding altered tactile experiences in neurodevelopmental disorders, such as autism spectrum disorder.

Methods

In this cross‐sectional study, 142 children and adults aged 3–23 years completed a vibrotactile testing battery consisting of 5 tasks, which rely on different cortical and cognitive mechanisms. The battery was designed to be suitable for testing in young children to investigate how tactile processing changes from early childhood to adulthood.

Results

Our results suggest a pattern of rapid, age‐related changes in tactile processing toward lower discrimination thresholds (lower discrimination thresholds = greater sensitivity) across early childhood, though we acknowledge limitations with cross‐sectional data. Differences in the rate of change across tasks were observed, with tactile performance reaching adult‐like levels at a younger age on some tasks compared to others.

Conclusions

While it is known that early childhood is a period of profound development including tactile processing, our data provides evidence for subtle differences in the developmental rate of the various underlying cortical, physical, and cognitive processes. Further, we are the first to show the feasibility of vibrotactile testing in early childhood (<6 years). The results of this work provide estimates of age‐related differences in performance, which could have important implications as a reference for investigating altered tactile processing in developmental disorders.