bluuebunny/crossref_metadata_2025 huggingface dataset:
Digital Media and EdTech-Based Instruction for Students and Teachers with Disabilities in Jordan
Authors: Alzubi Ahmad
Published: October 2024

There is a need for evaluations to help us understand the associations found in research on special education and new media. The researcher in this study explores the role of digital media in public education, with a specific emphasis on the role of digital media in the education of students with special needs and other types of disabilities. We used qualitative studies for our investigation. Under this pedagogical framework, it will provide helpful materials for digital media teachers and students who may not be fully aware of the benefits and significance of special education in the context of digital media instruction and education. Because there aren't enough studies on the subject, the sample size for this article is 12. The special edition on digital media and educational technology-based education for children with impairments. Initially, the selected pieces were dispersed in 2020 and 2022. Information required for the review's assessment was assembled by classifying the collected data according to the review's rubric. The review is the most useful tool for this assessment since it provides the best method for arranging both large amounts of data and personal judgments. In addition to describing how instructors and library media workers may work together to address the needs of children with disabilities, this article gives an overview of both physical and digital access to the library's resources. Research conducted by specialists has shown a positive correlation between all of these biomarkers.
E-Learning in Elementary Education: An Analytical Study on Its Effectiveness
Authors: Daud Khalid
Published: October 2024

This study aims to assess the effectiveness of electronic learning (e-learning) as perceived by Aspiring Elementary Teachers in Tubod, Lanao Del Norte. The research addresses the growing role of e-learning in education and its impact on teaching practices and student outcomes. A descriptive research design was utilized, with data collected through surveys administered to a sample of Elementary Pre-Service Teachers. The analysis focused on the aspiring teachers' perceptions of how e-learning influenced their teaching methods, classroom engagement, and access to resources. The results indicate that e-learning significantly enhances instructional quality, allowing for greater flexibility in lesson delivery and fostering improved engagement with students/pupils. Teachers also reported that e-learning promotes a more personalized learning experience, adapting to various student needs and learning styles. Additionally, the study found e-learning to be cost-effective, reducing reliance on physical resources and travel. These findings suggest that e-learning is a valuable tool in modern education, contributing to more innovative and efficient teaching practices. The implications of this study highlight the importance of continued investment in e-learning technologies to support educators in adapting to evolving educational demands. The study underscores the growing need for technology integration in education to optimize teaching effectiveness and improve learning outcomes.
ANÁLISE DE NÍVEIS DE PRESSÃO SONORA EM PRAÇAS DE ALIMENTAÇÃO: ESTUDO DE CASO DOS SHOPPINGS CENTERS DE UBERABA – MG
Authors: Barbosa Michele Cristina Rufino , Tiago Felipe Batista , Saturi Gabriel Silva
Published: October 2024

A poluição sonora é a terceira maior poluição que afeta a população mundial. Elevados níveis de ruídos causam problemas de saúde e geram diversos efeitos psicológicos e fisiológicos. À medida que as cidades se desenvolvem os níveis de ruídos crescem e a tendência, nos centros urbanos, é a substituição das praças de lazer ao ar livre pelos shoppings centers. Dentro do ambiente de shoppings centers se destaca as praças de alimentação, onde têm sido observados problemas de desconforto acústico. O presente estudo verificou se os níveis de ruídos de duas praças de alimentação de dois shoppings da cidade de Uberaba-MG estão dentro dos padrões estabelecidos por normas e o quanto estes ruídos estão afetando a saúde e o bem-estar das pessoas. Foram realizadas medições de ruídos de fundo e ruídos de fonte + fundo de acordo com os critérios instituídos pela NBR 10.151/2000. Ambos os ruídos estavam acima do limite máximo de conforto acústico estabelecido pela NBR 10152/2017 e também pelo recomendado pela Organização Mundial de Saúde. Dessa forma a saúde das pessoas que frequentam as praças de alimentação estudadas, está sujeita a riscos. Recomenda-se um estudo sobre alterações arquitetônicas das praças e a criação de um programa de conscientização por meio de campanhas educativas.
O “PRINCÍPIO RESPONSABILIDADE” DE HANS JONAS: DISCUSSÕES ATUAIS SOBRE SUSTENTABILIDADE
Authors: Rodrigues Tayronne de Almeida , Neto João Leandro , Silva Francisco Mário de Sousa
Published: October 2024

Esta pesquisa objetivou refletir sobre, históricas e atuais interações socioambientais. Para tanto, utilizou-se de revisões teóricas enfatizando, “o princípio responsabilidade”, promovido pelo teórico Hans Jonas, importante filosofo que viveu durante o período da Segunda Guerra Mundial e do Holocausto Judeu; tais acontecimentos motivaram suas pesquisas e influenciaram decisivamente na construção do “princípio responsabilidade”, o qual estabelece importantes interações com os conceitos de sustentabilidade e desenvolvimento sustentável. No estudo, apresenta-se um panorama dos problemas ambientais, onde se percebeu dicotomia nas históricas e atuais formas de atuação da humanidade para com a natureza, o que motiva novas compreensões acerca do compromisso ético do homem para com o meio ambiente. Para tanto, a revisão sobre “o princípio responsabilidade” do filósofo Hans Jonas, motivou importantes considerações estabelecidas nessa pesquisa. Sendo assim, ressalta-se a relevância do tema, frente às atuais configurações do mundo contemporâneo. Portanto, a responsabilidade ambiental deve ser refletida nos diferentes setores socioculturais, de forma a ser valorizada e colocada em prática, buscando fomentar técnicas educativas capazes de legitimar novas interações, haja vista o avanço nas pesquisas e a progressão no conhecimento nesse campo, frente às atuais demandas socioambientais.
Descubre la opción más económica para calentar agua en el hogar en México: gas natural, gas LP o electricidad
Authors: González Bravo Humberto Eduardo , Dorantes Rodríguez Rubén , Vengoechea Pimienta Alejandra Manuela , Ramírez-Muñoz Jorge
Published: October 2024

El aumento en los costos de energía eléctrica ha despertado un mayor interés en la población en usarla de manera más eficiente. La proliferación de condominios verticales en las ciudades genera desafíos para satisfacer las necesidades de electricidad y gas debido a la alta densidad de habitantes. Aunque los calentadores solares de agua se han vuelto populares, en edificios de más de cinco pisos esta opción es limitada por la distancia y falta de espacio para todos los residentes. En muchos casos, la única opción viable para calentar agua es el uso de gas natural, gas LP o electricidad. En ciudades grandes, el gas natural es común en nuevos edificios, y el uso de gas LP está restringido por motivos de seguridad. Un análisis técnico-económico mostró que, aunque la electricidad no es la forma más eficiente de calentar agua, su costo es más bajo que el del gas natural y LP, gracias a los subsidios gubernamentales para hogares de bajo consumo. En un ejemplo evaluado, el costo del gas natural y LP fueron 2.2 y 1.6 veces más altos que el de la electricidad, lo que hace a esta última una opción más económica.
BERSATU DALAM PERBEDAAN
Authors: Anouw Yulian , Wattimury Wiesye Agnes , Tata Marche Eka Risty
Published: October 2024

Bersatu adalah penting di dalam sebuah masyarakat apalagi jemaat, karena bersatu merupakan senjata yang dapat mengalahkan ancaman dunia yang begitu mempesona dengan segala kepraktisannya. Perbedaan adalah sesuatu yang berlainan atau tidak sama, baik dalam tindakan maupun pandangan tentang suatu keadaan. Sudah tidak heran lagi kalau pertumbuhan serta perkembangan gereja dimana-mana sedang terjadi. Dapat diketahui bahwa disamping pertumbuhan serta perkembangannya, dapat dilihat bahwa dimana-mana juga ditemukan perpecahan didalam gereja pada masa kini. Penyebab dari perpecahan jemaat ini terjadi karena adanya kepentingan pribadi kelompok yang kemudian mempengaruhi jemaat, sehingga mereka menjadi egois, serakah, iri hati, dengki, dan selalu memprofokasikan orang lain serta mencampuri urusan politik dengan gereja. Mereka selalu membawa masalah politik kedalam suatu persekutuan berjemaat, sehingga sering kali terjadinya konflik dalam berjemaat dan terjadilah perdebatan di dalamnya yang mengakibatkan perpecahan jemaat atau gereja. Penelitian ini menggunakan penelitian kualitatif seperti wawancara secara langsung serta mencatat dokumen untuk menggumpulkan data yang akan digunakan sebagai penunjang penelitian. Semua data diolah secara kualitatif dan setiap data yang diperoleh dari analisis data. Dari hasil penelitian yang dilakukan di Jemaat GMIH Rehoboth sambiki baru dapat disimpulkan bahwa, akibat dari perpecahan yang terjadi di jemaat adalah kepentingan pribadi dan juga sifat keegoisan yang tinggi serta berbeda pendapat dan juga kurangnya pengetahuan tentang kebenaran Tuhan. Kebanyakan orang pada saat ini lebih mementingkan kepentingan pribadi dibandingkan dengan kepentingan tentang kebenaran Tuhan atau perintah-Nya yang dimana setiap orang yang percaya kepadaNya harus melaksanakan perintah-Nya untuk membritakan injil serta menjaga kesatuan dan keharmonisan persekutuan.
Determinants of Food access and Diet quality of Women of Reproductive age from fish farming households in Western Kenya
Authors:   Department of Human Nutrition, Faculty of Health Sciences, Egerton University, Kenya, Cheserek1 Maureen Jepkorir , Ogello2 Erick Ochieng ,   Department of Fisheries and Natural Resources, Maseno University, Kenya, Obiero3 Kevin Odhiambo
Published: October 2024

This study investigated factors affecting household food access and diet quality of women of reproductive age within fish farming households in Western Kenya during COVID-19 pandemic period. A crosssectional study was conducted among 138 women with children aged 6-59 months from registered vulnerable and marginalized farmer groups in rural communities of Kakamega, Siaya and Busia counties. Almost half (47.1%) of the fish farming households experienced severe food insecurity with only 1.4% being food secure. Female headed households (AOR=0.082; 95% CI, 0.094-0.802; P<0.05) and unmarried women farmers (AOR=5.616, 95% CI, 1.257-2.429, P<0.05) were more likely to be food insecure. Overall, 47.1% of fish farming households experienced severe food insecurity with only 1.4% being food secure. Female-headed households and unmarried women farmers were more likely to be food insecure. Further, only a third of women (30%) met minimum dietary diversity, with those from female-headed households (AOR=0.046, 95% CI, 0.004-0.497, P<0.05) consuming a less diverse diet, and those from households where food availability was affected by COVID-19 pandemic (AOR=2.331, 95% CI, 1.024-5.305, P<0.05). However, women who were aware of dietary diversity and included value-added fish products in their meals consumed a diverse diet. In conclusion, women consumed poor quality diets due to the negative effects of COVID-19 pandemic on household food access and lack of awareness on dietary diversity. There is a need to improve food access among fish farming communities and enhance diet quality through nutrition education and social behaviour change communication. Food access and diet quality of women from fish farming households Key terms: Diet quality; Fish Farming Households; Food Access: Women of reproductive age
Prevalence and determinants of stunting in children under the age of five, in Bisho, South Africa
Authors: Beyleveld1 Janine , Gresse2 Annelie ,   Department of Human Nutrition and Dietetics, Nelson Mandela University, Port Elizabeth, South Africa
Published: October 2024

Childhood stunting is the most prevalent form of chronic malnutrition, affecting 149 million children under the age of five worldwide. As the determinants of stunting are complex and multicausal, it is important to look at area specific determinants and determine whether these are similar to the general determinants. This study investigated the prevalence and determinants of stunting in children under the age of five, visiting Bisho Hospital clinic in the Eastern Cape, South Africa. A cross-sectional, qualitative design was used. All children under the age of five, visiting Bisho Hospital’s clinic during the data collection period, and whose mothers provided consent, were included in the sample of 219 participants. An interview-administered questionnaire was used to determine possible factors that may play a role in stunting. Anthropometrical measurements (height, weight and mid-upper arm circumference) were used to calculate z-scores for the children. IBM SPSS Statistics 26 (version 24.0) was used for statistical analysis. Dietary diversity was calculated with a seven food group classification. The prevalence of stunting was 47.5 %, of which 57.7 % were classified as moderately stunted, and 42.3 % severely stunted. There was a significant correlation between the participants’ main form of sanitation and stunting in all age groups (p = 0.007; Cramer’s V = 0.413 and p = 0.04; Cramer’s V = 0.326, respectively). A statistical significance was found between the child support grant and stunting (p = 0.032) in children younger than six months, but not in the older group. No statistical significance was found between other determinants of stunting that were analysed. As stunting is multi-causal, it requires a combination of nutrition-specific and nutrition-sensitive interventions, together with strong political and financial commitment from stakeholders to eradicate stunting in children. Keywords: Stunting, Children, Sanitation, Infections, Breastfeeding
Yacon Based Snacks: A Source of Fructooligosaccharides, Phenolic Compounds, Antioxidant Activity and Low Glycemic Index.
Authors:   1Dedan Kimathi University of Technology Institute of Food Bioresources Technology Nyeri, Kenya., Miringa1 Grace Ng’endo
Published: October 2024

Yacon is a sweet-tasting Andean tuber that is grown in South American countries, China etc. but not very well known in Kenya. It has been used in the formulation of various products e.g. yacon syrup, yacon candies, yacon flour used to make cakes, biscuits etc. Yacon is a functional food due to the nutritional value of its composition represented by its fructooligosaccharide content. Snacking is the most common social activity and is generalized by high carbohydrate content thus the leading cause of non-communicable diseases. Therefore, development of snacks with health benefits is an opportunity for the food sector. The present review aims to broaden discussions of the functional properties attributed to snacks formulated with yacon flours, which possess beneficial properties i.e. high protein, fiber, antioxidants and total polyphenols contents. Its prebiotic and low glycemic index properties essential for prevention of noncommunicable diseases. According to studies done, biscuits formulated with yacon flours have recorded high protein, fat, mineral and fiber content as compared to wheat flours. Fiber contents are greatly increased with addition of yacon flour due to high fructooligisaccharide. A snack formulation of banana flours and yacon flours showed an increase in the antioxidant activity and total polyphenol content greatly attributed to the yacon flour added. Snack formulations with yacon flour have shown high amounts of slow digestible starch and resistant starch that attribute to low glycemic index thus very beneficial for diabetic patients. The fructooligosaccharide in yacon that is greatly retained in yacon flours is not digestible by the human enzymes thus after consumption it is selectively fermented in the colon by a group of bacteria mostly, Bifidobacterium, thus a prebiotic. It modulates the intestinal microbiota thus facilitating the exclusion of potential pathogens by competition and modulating the immune system increasing defenses of the host. There are few studies done on this, clinical evidence is scarce, making it necessary that more studies are done. The availability of yacon is still new; its popularity depends on publications aimed at consumer education and new product development by food industries. Keywords: Yacon, snacks, glycemic index, prebiotics, antioxidants.
Huono-osaisuuden kasautumisen yhteys ammatillisten opintojen keskeytymisen riskiin
Authors: Holappa Anna-Sofia , Pakarinen Eine , Pehkonen Aini
Published: October 2024

Artikkelissa tarkastellaan ammatillisten opintojen keskeytymisen riskiin yhteydessä olevia huono-osaisuustekijöitä ja niiden kasautumista. Aineistona on kolmesta ammatillisesta oppilaitoksesta kerätty kysely (n=355), jota analysoitiin ristiintaulukoinnin, χ²-riippumattomuustestin, logistisen regressioanalyysin ja varianssianalyysin avulla. Tulosten mukaan kuusi selittävää tekijää on yhteydessä opintojen keskeytymisen riskiin: ikä, erityisen tuen päätös, kokemus huonosta taloudellisesta tilanteesta, vähintään satunnainen päihteidenkäyttö, kokemus heikosta psyykkisestä terveydestä sekä kokemus vanhempien kiinnostumattomuudesta nuoren opintoja kohtaan. Opintojen keskeytymisen riskiryhmään kuuluvista nuorista 86 prosentilla oli vähintään kolme huono-osaisuustekijää. Keskeytymisen riskiä lisäävät tekijät kuvaavat taloudellisen, sosiaalisen ja terveydellisen huono-osaisuuden ulottuvuuksia. Huono-osaisuuden kasautuminen on merkittävä tekijä syrjäytymisen prosessissa.
Asiasanat: ammatilliset opinnot, huono-osaisuus, kasautuminen, nuoret
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The association between the accumulation of disadvantage and the risk of dropping out of vocational educationAnna-Sofia Holappa, Eine Pakarinen & Aini Pehkonen
The Finnish Journal of Youth Research(Nuorisotutkimus) Vol 42 (3), 3–19
The article examines the disadvantages associated with the risk of dropping out of vocational education and their accumulation. Data collected from a survey conducted in three vocational institutions (n=355) were analyzed using cross-tabulation, χ² independence tests, logistic regression analysis, and analysis of variance. The results indicate that six factors are associated with the risk of dropping out: age, decision to receive special support, experience of poor financial situation, at least occasional substance use, experience of poor mental health, and experience of parental disinterest in the adolescent’s studies. Of the adolescents identified as being at risk of dropping out, 86% had at least three disadvantage factors. The factors that increase the risk of dropping out reflect the dimensions of economic, social, and health-related disadvantage. The accumulation of disadvantage is a significant factor in the process of social exclusion.
Keywords: vocational education, disadvantage, accumulation, adolescent
International Research Cooperation in The Tallin Manual
Authors: Clark Ian
Published: October 2024

Contemporary military strategy exhibits a growing dependence on operations conducted within the domain of cyberspace. These operations are increasingly capable of inflicting tangible harm in the physical world, degrading essential infrastructure, and inducing widespread disruption. Nevertheless, a debate persists regarding the applicability of established international legal frameworks governing armed conflict to cyberwarfare. The Tallinn Manual, a non-binding academic study exploring the intersection of international law and cyberwarfare, plays a pivotal role in disentangling this complex debate by bridging international law, professional military ethics, and technical disciplines. In addition to being an indispensable guide to the legality of cyberwarfare operations, this paper argues that the Tallinn Manual represents a successful example of interdisciplinary collaboration and international cooperation, which may serve as a model for addressing a myriad of challenging legal and moral realities.
STAKEHOLDERS’ SUPPORT FOR THE SUSTAINABLE DEVELOPMENT OF READERSHIP PROMOTION CAMPAIGN AT THE NATIONAL LIBRARY BRANCHES IN NORTH-WEST, NIGERIA
Authors: Abubakar Hindatu Salisu
Published: October 2024

The study investigated into the stakeholder’s support for the sustainable development of readership promotion campaign (RPC) in the National Library branches in North-west, Nigeria. The objectives of the study were to: find out if stakeholders have been supportive to the RPC, the extent to which they have been supportive to the RPC as well as determine the type of supports received from the stakeholders for the RPC in the National Library. The quantitative research methodology was adopted for the study using the cross-sectional survey design. Total enumeration sampling technique was used to collect data from a total of 20 librarians in the five National Library branches and questionnaire was used as the data collection instrument. The findings of the study reveal that: the stakeholders have been supportive to the RPC, the extent to which the stakeholders have been supportive to the RPC is low and that the major supports received from the stakeholders included: book donation, giving talks or lecture and participation while some other important supports like: funding, media coverage, and cash donations, were not adequately provided nor received. The study concludes that librarians have been receiving supports from stakeholders, but the extent to which the support is received is grossly inadequate. There is therefore the need for librarians to provide more means of encouraging stakeholders on the need for more supports as well as encourage them as community members to engage into the program for an enhanced literacy development and for an effective, efficient and sustained RPC. The study therefore recommends that librarians should be more proactive in enlightening stakeholders on the importance of the RPC and the need for them to be more knowledgeable on the type of supports needed for the sustainable development of RPC in the National Library branches in North-west, Nigeria.
Financial Distress Prediction Using an Artificial Neural Network Integrating a Two-Stage Feature Selection Method
Authors: Zhang Zijiao , Qu Shiyou , Wu Chong
Published: October 2024

Financial distress prediction (FDP) is critical for companies, banks, and investors, and artificial neural networks (ANN) have been proven to be an efficient method for FDP. However, the “curse of dimensionality” in FDP not only increases the computational complexity, but also reduces the prediction accuracy. To solve this problem, this paper takes an ANN model as the basic classifier and presents a new two-stage feature selection method integrated with multiple filters and a wrapper method. The financial data of Chinese listed companies are applied for comparative analysis to verify the effectiveness of the constructed method. The results demonstrate that the proposed method achieves a smaller feature subset and better predictive effect than other methods, thus solving the “curse of dimensionality” more effectively and improving the accuracy. In addition, SHapley Additive exPlanations (SHAP) and Partial Dependence Plots (PDP) are employed to investigate the relative importance of selected features. Their results increase the credibility of the proposed model, giving users more confidence in using this “black box” model.
The Effects of Green Intellectual Capital on Business Performance: Evidence from Serbia
Authors: Vukmirović Valentina , Radonić Milenko , Radovanović Olga , Milosavljević Miloš
Published: October 2024

Investing in green intellectual capital can create competitive advantage of companies in the long term. In short term, however, more orchestration is required for investment into green resources to boost financial and non-financial performance of business. The aim of this paper is to present the effects of Green Intellectual Capital (Green Human Capital, Green Structural Capital, and Green Relational Capital) on companies' business performance (including their financial and non-financial indicators). For this purpose, primary data were collected from targeted companies operating in the Serbian market (N=344) using a structured questionnaire. The results confirm the positive effects of Green Human Capital and Green Relational Capital on both financial and non-financial indicators of researched companies. Green Structural Capital was not found to have an impact on the companies' financial performance. These findings can contribute to 1) owners and managers in creating sustainable business models, 2) regulators in creating policy frameworks and incentives for sustainable development and 3) other business analysts focused on the green intellectual capital development in companies.
Too Much of a Good Thing? Two-Sided Effect of ESG on Corporate Financial Performance
Authors: Teng Xiaodong , Wang Shouhai , Liu Huiping , Sun Wengang , Zhu Desheng , Wu Kun-Shan
Published: October 2024

The purpose of this research is to clarify the curvilinear link between Environmental, Social and Governance (ESG) and corporate financial performance (CFP), and draws upon the “too much of a good thing” (TMGT) theory to verify whether the curvilinear relationship supports the conflicting results of previous studies. The sample comprises 69 listed companies in Taiwan with ESG disclosures over 2005 to 2020. The findings reveal that ESG impacts CFP in an inverted- U shaped, which is predominantly evident in the environmental and social pillars. This study validates the rising popularity of ESG investments. To enhance CFP, businesses must meticulously assess the allocation of capital to ESG to prevent under or over-investment. Managers should be aware of the TMGT effect and ensure the threshold of ESG is identified, as this is essential to balancing the cost/value trade-off, improving the CFP, and maintaining sustainable development.
Der Einfluss und rechtliche Rahmen von Geoblocking im Onlinevertrieb
Authors: Burkert Robert
Published: October 2024

With Regulation (EU) 2018/302, the EU legislator has significantly changed the legal framework for discrimination against end customers on the basis of geographical characteristics (“geoblocking”) in online retail. These regulations, which adding to the existing provisions, in particular under competition law, pose numerous challenges for the e-commerce practice. This book examines the new regulatory framework for geoblocking in online retail and clarifies key practical issues in dealing with the provisions of the Geoblocking Regulation. It analyzes the question of whether the EU legislator has achieved its aim of creating an uniform legal framework for geoblocking.
Möglichkeitsarchitektur im Werk Paul Scheerbarts
Authors: Mussack Amelie
Published: October 2024

The literary architecture in Paul Scheerbart's narrative work is analyzed systematically and interdisciplinarily for the first time. The fantastic buildings in the novels and treatises react to changes and upheavals of the early 20th century. In this way, Scheerbart reflects on questions of material and reception aesthetics just as he takes up architectural discourses. Literary architecture first functions as part of a utopia before increasingly becoming a utopia itself. For their part, his architectural designs had an effect beyond the fictional medium, inspired contemporary architectural theory, and gained factual presence: Bruno Taut, for example, realized Scheerbart's Glasarchitektur (1914) in an exhibition building.
Dipeptidyl Peptidase-4 Inhibitors: A Systematic Review of Structure-Activity Relationship Studies
Authors: Bayanati Maryam , Ismail Mahboubi Rabbani Mohammad , Sirous Kabiri Shirin , Mir Bahareh , Rezaee Elham , Tabatabai Sayyed Abbas
Published: October 2024

Context: Dipeptidyl peptidase 4 (DPP-4) is a serine exopeptidase enzyme that hydrolyzes the amide bond at the N-terminal of peptides. This enzyme converts incretins, such as glucagon-like peptide I and glucose-dependent insulinotropic peptide, into their inactive forms, thereby preventing them from stimulating insulin secretion. Numerous studies have confirmed the role of DPP-4 in the pathophysiology of type 2 diabetes, leading to the development of various DPP-4 inhibitors. In recent years, research on DPP-4 inhibitors has expanded significantly, resulting in the creation of both non-peptidomimetic heterocyclic compounds and peptidomimetic scaffolds. Evidence Acquisition: This systematic review summarizes all recent advances related to DPP-4 inhibitors up to 2024. It begins by outlining the biochemical characteristics of DPP-4 and general pharmacological principles of DPP-4 inhibition, followed by an overview of the latest developments from recent publications. The review provides valuable insights into the pharmacophores necessary for ligand-protein interactions, aimed at understanding the structure-activity relationship of novel DPP-4 inhibitors. Data for this review was collected from sources including ScienceDirect, PubMed, and Scopus. Results: This review highlights various chemical scaffolds that have been explored in the development of novel DPP-4 inhibitors. It emphasizes scaffolds with significant DPP-4 inhibitory activity, including azoles, azines, sulfonamides, and quinolone motifs. The article also details the structure-activity relationships of newly developed analogs, providing a comprehensive overview of recent advancements in this area. Conclusions: Despite moderate progress in the development of novel DPP-4 inhibitors, emerging molecular aspects of DPP-4 intervention show great promise for future therapeutic developments.
Prevalence and Risk Factors of Surgical Site Infection Following Cesarean Section
Authors: Rakhshani Moghaddam Firoozeh , Razavi Maryam , Delaramifar Zahra
Published: October 2024

Background: Surgical site infection (SSI) following Cesarean section (C-section) is a common cause of morbidity and imposes a significant load on the healthcare system. Therefore, the prevalence of factors that make individuals more susceptible to SSI after a C-section should be accurately assessed. Objectives: This study aimed to determine the frequency and risk factors for infection following C-section in women referred to the maternity ward of Ali ibn Abi Talib Hospital in Zahedan, Iran, from 2020 to 2022. Methods: This descriptive cross-sectional study was performed on all women admitted to the maternity ward of Ali ibn Abi Talib Hospital in Zahedan, whether undergoing elective or emergency C-sections. The patients were entered into the study with informed consent and were followed up to one month after surgery. Results: This study showed that approximately 5300 cases of C-sections were performed in Ali ibn Abi Talib Hospital during the mentioned period, of which 120 patients were referred to this hospital again because of surgical site infections. The occurrence of SSI in the present study was 2.26%, and obesity and anemia were identified as the predominant risk factors. The findings showed that the incidence of patients with SSI following a C-section with obesity, anemia, skin scar of previous C-section, rupture of membranes before C-section (> 6 hours), and diabetes mellitus were 80, 76.8, 36.7, 33.3, and 24.2 %, respectively. Conclusions: The recorded incidence of SSI following C-section was comparatively lower than findings from prior studies conducted in developing countries. Although the frequency of these complications is desirable, there are the same number of irreparable complications to mothers and infants and high costs for families and society.
PENGUJIAN KADAR AIR PADA PRODUK PANGAN KERUPUK MARUKU CHAN
Authors: Febriansyah Muhammad , Amalina Nur , Hidayat Deski , Muslima Muslima , Pazira Zira , Fithriyyah Hulwah
Published: October 2024

Salah satu produk olahan tradisional yang banyak dikonsumsi di Indonesia adalah kerupuk. Kerupuk merupakan salah satu jenis camilan yang banyak disukai oleh masyarakat. Teksturnya yang renyah dan rasa gurih yang dimiliki kerupuk menjadi salah satu faktor yang berpengaruh terhadap penerimaan konsumen. Salah satu produk yang bisa dikembangkan adalah kerupuk maruku chan dari bahan baku tepung ketan dengan selalu memperhatikan kandungan gizinya salah satunya yaitu kadar airnya. Tujuan dari kegiatan ini adalah untuk menguji kadar air pada produk pangan yaitu kerupuk maruku chan. Kegiatan ini menggunakan pendekatan kuatitatif yaitu data berupa angka yang didapatkan secara langsung. Hasil dari kegiatan ini adalah kadar air pada kerupuk maruku chan mengalami kenaikan berat 1 gram karena faktor pemanasan mapun timbangan tersebut. Hal tersebut karena adanya reaksi yang menghasilkan air atau zat yang mudah menguap, seperti dekomposisi gula, karamelisasi, atau oksidasi lemak selama proses pemanasan. Pengujian kadar air pada produk pangan sangat penting karena erat hubungannya dengan penampakan, tekstur, cita rasa, dan keawetan suatu produk. Kesimpulan dari kegiatan ini adalah kadar air pada kerupuk maruku chan mengalami kenaikan bobot 1 gram pada pemanasan kedua selama 1 jam dikarenakan faktor pemanasan, kontaminasi, maupun timbangan tersebut.
Kurumsal Bilgi Güvenliği Yönetiminde Yapay Zekâ Destekli Risk Analizi
Authors: Coşar Mustafa
Published: October 2024

Yaşamın giderek dijitalleştiği bilgi çağında, bilginin değeri ve önemi her geçen gün artmaktadır. Bilginin değerini ve önemini artırmanın esas yolu; onun gizliliği, güvenliği ve bütünlüğü unsurlarını korumaktan geçmektedir. Bu unsurların tümü pek çok bileşenin ve faktörün bir arada olduğu, sürekli ve çok yönlü etkileşimde bulundukları bir sistemi oluşturmaktadır. Bu sistemin yapısı gereği pek çok riski de beraberinde getirmektedir. Bu risklerin önceden belirlenmesi, hesaplanması ve analiz edilmesinde iyi bir risk yönetim anlayışına ihtiyaç vardır. Bilişim teknolojileri bu yönetim anlayışına destek olmak için pek çok yeni yöntem ve teknik ortaya koymaktadır. Yapay zekâ yöntem ve teknikleri buna örnek olarak verilebilir. Bilgi güvenliğini sağlama aşamasında ortaya çıkan açıkların, eksiklerin ve risklerin yapay zekâ ile önceden belirlenerek önlemlerin alınmasında önemli roller üstlendiği görülmektedir. Özellikle veri toplama, işleme ve karar verme süreçlerini kapsayan veri analitiği ile tahmin etme ve karar vermeyi kolaylaştırmaktadır. Ayrıca, veri iletimi ve erişimi sırasında oluşan anormal durumların tespitinde makine öğrenimi ve doğal dil işleme algoritmaları önemli başarılar elde etmektedir. Bu çalışma, kurumsal bilgi güvenliği yönetiminde yapay zekâ destekli risk analizine değinmektedir. Bu kapsamda kullanılan yapay zekâ uygulamalarının özellikleri açıklanırken, yapay zekâ destekli örnek bir risk analizi modelini oluşturulmuştur. Bu model içerisinde yapay zekâ yöntem, teknik ve araçları belirtilmiştir. Ayrıca, yapay zekânın, bilgi güvenliği alanında risk analizi süreçlerine entegrasyonu ve potansiyel faydaları üzerinde durulmaktadır. Çalışmada, önerilen modelde yer alan yapay zekâ tekniklerinin ve modellerinin risk analizi aşamalarına uygunluğu araştırılırken uygulama temelli ilişkilendirmeler yapılmıştır. Çalışmanın diğer bir amacı ise, geleneksel risk analizi yöntemlerine kıyasla yeni nesil bilişim teknolojileri desteğiyle oluşturulan yöntemlere yönelik farkındalığın artırılmasıdır.
Fear as a Political and Anti-political Emotion
Authors: Vargas González Jessica ,   Department of Philosophy, Florida State University
Published: October 2024

A conception of fear as a negative emotion in politics is unsatisfactory. There are threats to democracy that should probably be feared. This paper defends the claim that a more nuanced normative assessment requires distinguishing between fears that are anti-political and those that are properly political. I propose two criteria to discern the sense in which certain fears may be appropriate in political life. Likewise, I argue that an analysis of fear in politics requires acknowledging our non-ideal selves (specifically, our cognitive and social biases) to better understand the dangers and potentialities present in the collective mobilization of fear in the public realm.
Oranjerivierafrikaans, ŉ Argeologiese Genealogie. Deel II. 1917-1979
Authors: Staphorst Luan
Published: October 2024

Dié tweede deel van ŉ vierdelige artikelreeks ondersoek die geskiedenis van die sosiolinguistiek relatief tot Oranjerivierafrikaans, een van die drie hoofdialekkontinuums van Afrikaans, van die periode 1917 tot 1979. Begrond in die linguistiese geskiedskrywing in die breë, en Michel Foucault se argeologiese en genealogiese oriënterings in die besonder, skets die artikeldeel hoe die intellektuele geskiedenis van Oranjerivierafrikaans in die tydsgees van die diskoers van ras- en taalverbastering van 1917-1939, en die tydsgees van die taalatlas van 1940-1979, daar uitgesien het. Hierdie periode sien die vestiging van Afrikaanstalige taalkunde. Die optekenings van ondere andere Gideon von Wielligh, Stephanus Boshoff, John Rademeyer, Abel Coetzee, en Stephanus Louw word bespreek. Hierdeur daag die artikelreeks vier sentrale veronderstellings oor die taalvorm uit, naamlik dat daar ŉ gebrek aan bronne oor die taalvorm is, dat dit redelik “onsigbaar” is, dat dit as ŉ Swart Afrikaanse taalvorm getipeer kan word, en dat Kaapse Afrikaans, eerder as Oranjerivierafrikaans, as die “oudste” vorm van Afrikaans beskou moet word. ______________________________________________________________________________________________________________________ This second part of a four-part article series investigates the history of sociolinguistics relative to Orange River Afrikaans, one of Afrikaans’s three main dialect continuas, from the period 1917 to 1979. Grounded in linguistic historiography broadly construed, and Michel Foucault’s archaeological and genealogical orientations specifically, this part of the article sketches how the intellectual history of Orange River Afrikaans in the period 1917-1979 can be divided into two Zeitgeists – the time of the discourse of racial and linguistic bastardization of 1917-1939, and the time of the linguistic atlas of 1940-1979. This constitutes the period of the establishment of Afrikaans-language scholarship. The writings of Gideon von Wielligh, Stephanus Boshoff, John Rademeyer, Abel Coetze, and Stephanus Louw are discussed. Through this, the article series challenges four central and dominant presuppositions on Orange River Afrikaans, namely that there are limited sources available relative to it, that it constitutes an “invisible” language form, that it can be typified as an expression of Black Afrikaans, and that Kaaps (Cape Afrikaans), rather than Orange River Afrikaans, should be regarded as the “oldest” form of Afrikaans.
The efficacy of game-based learning activities in enhancing L2 vocabulary acquisition among Saudi non-English majoring students
Authors: Al-Sofi Bakr Bagash Mansour Ahmed
Published: October 2024

Vocabulary acquisition is a crucial aspect of second language acquisition (SLA). To facilitate this process, many game-based learning (GBL) activities have been integrated into learning materials, including the New Headway Plus books. These books are specifically designed for adult learners of English in the Middle East and North Africa and are used to teach all freshmen at the University of Bisha in Saudi Arabia. This study has four main objectives: to identify the various types of GBL vocabulary activities included in the prescribed textbooks; to examine the extent to which these activities are efficacious in enhancing Saudi students' second language (L2) vocabulary acquisition; to identify students' perceptions of the role of GBL activities in enhancing their psychological factors; and to examine the impact of students' majors on vocabulary aspects and psychological aspects. Data for this study were collected from the selected books, question sheets for midterm and final exams, students' scores in these exams, and a questionnaire administered to 63 Saudi non-English majoring students. The analysis of the results revealed that various GBL activities were incorporated in the prescribed textbooks, such as crossword activities, picture-word and word-word matching, word scrambles, collocations, and categorization, with crosswords being the most prevalent. GBL activities proved to be efficient in enhancing their vocabulary and recalling previously learned words. Additionally, students had a positive perception of the role of these activities in enhancing their psychological factors. While students' majors were found to have a statistically significant impact on vocabulary acquisition, they did not have a statistically significant impact on psychological aspects such as motivation, engagement, self-confidence, interest, shyness, and collaboration. Recommendations are made to enhance students' L2 vocabulary acquisition.
ĐẶC ĐIỂM LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ VẢY NẾN MẢNG BẰNG LASER CÔNG SUẤT THẤP NỘI MẠCH
Authors: Phạm Vũ Hạ , Từ Tuyết Tâm
Published: October 2024

Đặt vấn đề: Vảy nến là một bệnh viêm mạn tính tác động hệ thống đến nhiều cơ quan và có ảnh hưởng đến khoảng 2% dân số trên thế giới. Vảy nến mảng là dạng lâm sàng thường gặp nhất của bệnh. Bên cạnh các phương pháp điều trị dùng thuốc, laser công suất thấp nội mạch được biết đến như một liệu pháp hỗ trợ với bước sóng từ 632,8nm-670nm và công suất từ 0-6 mW tác động điều hòa miễn dịch, tăng vi tuần hoàn. Tuy nhiên, có rất ít những nghiên cứu về hiệu quả của phương pháp này tại Việt Nam. Mục tiêu nghiên cứu: Mô tả đặc điểm lâm sàng ở bệnh nhân vảy nến mảng và đánh giá kết quả điều trị tại chỗ vảy nến mảng bằng laser công suất thấp nội mạch tại Bệnh viện Da liễu Cần Thơ năm 2023. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang, tại Bệnh viện Da liễu Thành phố Cần Thơ, gồm 76 bệnh nhân được chẩn đoán vảy nến mảng, được điều trị bằng laser nội mạch. Bệnh nhân được ghi nhận lại các đặc điểm lâm sàng và kết quả điều trị bệnh tại thời điểm điều trị 5,7,10 và 12 tuần. Thời gian nghiên cứu là năm 2022-2023. Kết quả: Vị trí thương tổn hiện tại ở da đầu chiếm tỷ lệ cao nhất (92,1%). Hiệu quả điều trị đáng kể được ghi nhận sau 5 lần chiếu với tỉ lệ giảm PASI 32,89% và tỉ lệ này tiếp tục tăng dần sau các lần điều trị. Sau khi kết thúc điều trị, ghi nhận đa số bệnh nhân đều có sự cải thiện với tỉ lệ 97,7% bệnh nhân đạt hiệu quả từ trung bình đến tốt. Kết luận: Bệnh vảy nến phân bố ở mọi lứa tuổi, sang thương tập trung nhiều nhất ở da đầu; laser nội mạch là một phương pháp hiệu quả trong điều trị vảy nến mảng với tỉ lệ giảm PASI tăng dần sau các lần điều trị.
ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ TĂNG SINH LÀNH TÍNH TUYẾN TIỀN LIỆT TRÊN BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÝP 2 BẰNG PHƯƠNG PHÁP CẮT ĐỐT NỘI SOI TẠI BỆNH VIỆN ĐA KHOA TRUNG ƯƠNG CẦN THƠ VÀ BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ
Authors: Võ Hiếu Nghĩa , Lê Quang Trung , Quách Võ Tấn Phát , Đàm Văn Cương
Published: October 2024

Đặt vấn đề: Tăng sinh lành tính tuyến tiền liệt là sự phát triển lành tính của tuyến tiền liệt làm cản trở dòng tiểu đi ra từ bàng quang. Những bệnh lý nội khoa nói chung, đái tháo đường nói riêng ảnh hưởng không nhỏ đến tỷ lệ biến chứng cũng như quá trình điều trị hậu phẫu của bệnh nhân. Mặt khác không ít Bác sĩ Niệu khoa chưa thật sự an tâm khi phẫu thuật trên bệnh nhân đái tháo đường. Xuất phát từ những thực tế khách quan đó, chúng tôi tiến hành nghiên cứu này. Mục tiêu nghiên cứu: Mô tả đặc điểm lâm sàng, cận lâm sàng và đánh giá kết quả điều trị tăng sinh lành tính tuyến tiền liệt bằng phương pháp cắt đốt nội soi qua đường niệu đạo ở người bệnh có kèm theo đái tháo đường týp 2. Đối tượng và phương pháp nghiên cứu: Nghiên cứu tiến cứu, mô tả cắt ngang trên 30 bệnh nhân tăng sinh tuyến tiền liệt có mắc đái tháo đường týp 2, điều trị bằng phương pháp cắt đốt nội soi từ tháng 3/2022 đến tháng 1/2024 tại Bệnh viện Đa khoa Trung ương Cần Thơ và Bệnh viện Trường Đại học Y Dược Cần Thơ. Kết quả: Lý do vào viện thường gặp là tiểu khó 46,7% và bí tiểu cấp 46,7%. Có 86,7% trường hợp đang mắc bệnh đái tháo đường và 13,3% trường hợp bản thân vẫn không biết đang mắc bệnh. Đường huyết trung bình khi vào viện là 10,64±4,44 mmol/L, giá trị trung bình HbA1c khi vào viện là 7,98±0,73%. Sau phẫu thuật 3 tháng: Điểm IPSS trung bình là 12,77±4,26 và điểm QoL trung bình là 2,6±0,86. Biến chứng gồm 3,3% chảy máu, 10,0% bí tiểu sau rút thông niệu đạo. Kết quả điều trị tốt chiếm 86,7%, khá chiếm 13,3%. Kết luận: Cắt đốt nội soi tăng sinh lành tính tuyến tiền liệt trên người đái tháo đường týp 2 đạt kết quả điều trị cao, triệu chứng lâm sàng và chất lượng cuộc sống cải thiện tốt khi kiểm soát tốt đường huyết trước, trong và sau phẫu thuật.
ĐÁNH GIÁ KẾT QUẢ SỚM PHẪU THUẬT THAY KHỚP GỐI TOÀN PHẦN LOẠI KHÔNG LIÊN KẾT ĐIỀU TRỊ THOÁI HÓA KHỚP GỐI
Authors: Lê Văn Hái , Huỳnh Thống Em , Nguyễn Văn Hết
Published: October 2024

Đặt vấn đề: Phẫu thuật thay khớp gối nhân tạo được chỉ định khi khớp gối bị thoái hóa nặng, đáp ứng kém với điều trị nội khoa. Hiện nay, có nhiều thế hệ khớp gối nhân tạo mới với những ưu điểm vượt trội, đem lại kết quả điều trị tích cực cho người bệnh. Mục tiêu nghiên cứu: Đánh giá kết quả phẫu thuật thay khớp gối toàn phần loại không liên kết tại Bệnh viện Đa khoa Hoàn Mỹ Cửu Long. Đối tượng và phương pháp nghiên cứu: Nghiên cứu cắt ngang mô tả tiến cứu 37 trường hợp được phẫu thuật thay khớp gối toàn phần loại không liên kết từ tháng 03/2023 đến 06/2024. Kết quả: Tuổi trung bình 66,54 ± 7,4 tuổi, điểm khớp gối trung bình trước mổ 38,92 ± 4,1 điểm, sau mổ 77,16 ± 7,12 điểm, điểm chức năng khớp gối trung bình trước mổ 37,16 ± 1,5 điểm, sau mổ 77,68 ± 4,5 điểm, biên độ gấp gối trung bình trước mổ 92,43o ± 4,3o, sau mổ 117,57o ± 4,35o, 91,9% bệnh nhân rất hài lòng và hài lòng về kết quả phẫu thuật. Kết luận: Thay khớp gối làm giảm đau, phục hồi biến dạng, cải thiện chức năng vận động khớp gối, mang lại chất lượng cuộc sống tốt hơn cho bệnh nhân bị thoái hóa khớp gối nặng.
NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CHẤT LƯỢNG CUỘC SỐNG CỦA BỆNH NHÂN VẢY NẾN MẢNG CÓ BỆNH NỀN NỘI KHOA TẠI CẦN THƠ NĂM 2022-2024
Authors: Lê Thị Như Ý , Ngô Minh Vinh , Nguyễn Hồng Hà
Published: October 2024

Đặt vấn đề: Vảy nến là bệnh lý da viêm mạn tính. Có nhiều bằng chứng cho rằng bệnh vảy nến là một rối loạn viêm đa hệ thống với nhiều bệnh lý đi kèm. Bệnh gây tổn thương trầm trọng về mặt tinh thần và chất lượng cuộc sống của bệnh nhân. Mục tiêu nghiên cứu: Mô tả đặc điểm lâm sàng và đánh giá sự ảnh hưởng của vảy nến mảng đi kèm bệnh nền nội khoa lên chất lượng cuộc sống của người bệnh. Đối tượng và phương pháp nghiên cứu: Nghiên cứu cắt ngang trên 126 bệnh nhân vảy nến mảng mức độ nhẹ đến trung bình có bệnh nền đồng mắc tại Cần Thơ. Kết quả: Độ tuổi trung bình là 53,1±16,2, tỉ lệ nam:nữ là 1:1,2. Triệu chứng chính là ngứa (81%). Trong đó có 73,8 % bệnh nhân ở mức độ trung bình. Bệnh nhân vảy nến mắc rối loạn lipid máu chiếm tỉ lệ cao nhất (78%). Tất cả các bệnh nhân đều đánh giá là có ảnh hưởng đến chất lượng cuộc sống, cao nhất ở nhóm bị ảnh hưởng rất lớn (43,7%). Bệnh nhân nữ có thang điểm DLQI cao hơn bệnh nhân nam và DLQI ở nhóm bệnh mức độ trung bình cao hơn nhẹ. Kết luận: Triệu chứng cơ năng phổ biến nhất là ngứa. Bệnh nội khoa đồng mắc đi kèm thường gặp nhất là rối loạn chuyển hóa lipid. Vảy nến ảnh hưởng ít nhiều đến chất lượng cuộc sống ở hầu hết các bệnh nhân vảy nến có bệnh nền nội khoa. Chất lượng cuộc sống của bệnh nhân vảy nến chịu ảnh hưởng bởi giới tính và mức độ trầm trọng của bệnh.