bluuebunny/crossref_metadata_2025 huggingface dataset:
Design of radionuclide separations based on MD simulations
Authors: Giménez Guerra Isaac , Sormani Giulia , Rodriguez Alex , Hassanali Ali , Bagán Hector , Tarancón Alex
Published: December 2024

The development of selective materials for radionuclide separation is often a long and costly process, requiring labor-intensive chemical separations and extensive optimization. To streamline the development of selective materials, this study explores MD simulations to accelerate the identification of optimal separation conditions, extractant-radionuclide affinity, reducing the need for extensive experimental trials. We assessed the effectiveness of MD simulations using the challenging system of Sr²⁺ and Pb²⁺ with 18-crown-6 crown ether, focusing on the influence of different working media, including nitric, hydrochloric, formic, acetic, and perchloric acids, as well as potassium thiocyanate. The simulation results were validated experimentally by measuring the distribution weight ratios (Dw) of Sr²⁺ and Pb²⁺ using crown ether immobilized on a polymeric surface. Our findings demonstrate a strong correlation between MD predictions and experimental data, particularly highlighting acetic acid as a medium where Sr²⁺ forms stable complexes, while Pb²⁺ does not. This study confirms the suitability of MD simulations as a reliable tool for predicting the selectivity of extractants, enabling faster development of new scintillating and non-scintillating resins. By reducing the time and resources needed for experimental optimization, this approach offers a more efficient pathway for the development of advanced materials for radionuclide separation.
First-Principles Molecular Dynamics with Potential and Charge Fluctuations Applied to Au(111) in Alkaline Solutions
Authors: Sechi Renata , Kastlunger Georg , Bhowmik Arghya , Hansen Heine Anton
Published: December 2024

Electrified solid-liquid interfaces play a crucial role in energy conversion, storage, photoconversion, sensors, and corrosion processes. While computational chemistry simulations can provide detailed insight into reaction mechanisms, aligning experimental and simulation results remains a significant challenge. In this work, we introduce the FDT-SJM method for ab-initio molecular dynamics simulations under potential control, where the electrode charge fluctuates around an average value following the fluctuationdissipation theorem (FDT), and electrode charges are screened by the solvated jellium method (SJM). The FDT-SJM is developed in GPAW, a Python-based, open-source DFT code. We validate this approach by simulating the Au(111) interface in pure water, KOH, LiOH, Li, and K solutions at several electrode potentials. We analyze water reorientation in response to changes in the electrode surface charge and demonstrate that the method enables the estimation of interface capacitance and the potential of zero charge, yielding values consistent with experimental data.
Biological Evaluation of Cleavable Linkers in Exatecan-Based Antibody-Drug Conjugates: A Comparative Study of DXd and Exo-Linker Platforms
Authors: Watanabe Tomohiro , Iwai Yusuke , Shikida Natsuki , Stofleth Jason T. , Seki Takuya , Shimbo Kazutaka , Matsuda Yutaka
Published: December 2024

Antibody-drug conjugates (ADCs) represent a transformative class of cancer therapies that combine the specificity of monoclonal antibodies with the cytotoxicity of potent drug payloads. This study presents the development and evaluation of a novel exolinker designed to enhance ADC stability and pharmacokinetics by addressing the limitations associated with traditional cleavable linkers. Using trastuzumab conjugated with a payload linker consisting of an exo-linker and exo-EVC-Exatecan (APL-1082), we examined key parameters, including in vivo efficacy and pharmacokinetic profiles in rat models, to directly compare it with the clinically validated trastuzumab-deruxtecan (T-DXd, Enhertu). Our Exo-linker ADC demonstrated superior stability and maintained drug-to-antibody ratios (DAR) with reduced aggregation and hydrophobicity compared to T-DXd, suggesting an improved pharmacokinetic profile. Additionally, combining the Exo-linker with AJICAP site-specific conjugation technology enabled the production of high-DAR ADCs, achieving a DAR of 10 with promising homogeneity and physicochemical properties. Collectively, these findings underscore the potential of the exo-linker as a versatile platform for next-generation ADCs, offering enhanced stability, efficacy, and expanded therapeutic possibilities.
Physics-assisted machine learning for slurry drying simulation in manufacturing process of battery electrodes: A hybrid time-dependent VGG16-DEM model
Authors: Galvez-Aranda Diego Eduardo , Fernandez Francisco , Franco Alejandro A.
Published: December 2024

In this study, we present a hybrid Physics-Assisted Machine Learning (PAML) model that integrates Deep Learning (DL) techniques with the classical Discrete Element Method (DEM) to simulate the slurry drying during a lithium ion battery electrode manufacturing process. This model predicts the microstructure evolution leading to the formation of the electrode, as a time-series along the drying process. The hybrid approach consists in performing a certain amount of DEM simulation steps, n_DEM, after every DL prediction, mitigating the risk of unphysical predictions, like overlapping particles. Our PAML model was rigorously tested by evaluating different functional metrics of the predicted electrodes, including density, porosity, tortuosity factor, and radial distribution function. We conducted an in-depth analysis of performance versus accuracy, particularly focusing on the impact of the n_DEM hyperparameter, which represents the number of DEM steps executed between two subsequent DL predictions. Despite the model being trained on a specific formulation (96% of Active Material, AM, and 4% of Carbon Binder Domain, CBD), it demonstrated exceptional generalization capability when used to extrapolate to a different formulation (94% AM and 6% CBD). This adaptability highlights the robustness of our PAML hybrid approach. Furthermore, the integration of DL significantly reduced the computational cost of the original DEM model, decreasing the processing time from 34.2 minutes per step to approximately 2 minutes per step. Our findings underscore the potential of combining ML with traditional simulation methods to enhance efficiency and accuracy in the field of electrode manufacturing.
PSYCHOLOGICAL FACTORS INFLUENCING MIGRATION DECISIONS AMONG HEALTHCARE PROFESSIONALS IN NIGERIA
Authors:   Dept. of Psychology, University of Ilorin, Nigeria, Alliu Sadiat Iyabode , Balogun Obasanjo Solomon ,   Dept. of Criminology and Security Studies, University of Ilorin, Nigeria
Published: December 2024

The mass migration of healthcare professionals from Nigeria, commonly referred to as “japa syndrome,” has left a significant gap in the country’s healthcare system. While economic and social factors in migration decisions are well-documented, the psychological dimensions remain significantly underexplored. This study aimed to identify key psychological factors and theoretical foundations explaining migration decisions and determine how these factors drive migration in Nigeria. This qualitative study was structured around two research questions: What psychological factors influence migration decisions? and how these psychological factors drive migration decisions and intentions. The study reveals that Nigerian healthcare professionals are driven by work-related stress, burnout, anxiety, and job insecurity, leading to migration for better opportunities abroad. These factors explained by Maslow's hierarchy of needs, push and pull theory, and cognitive dissonance theory, present a comprehensive understanding. The study suggests systemic changes to reduce migration pressures for healthcare workers, including stress management programs, improved working conditions, professional recognition, and effective retention strategies.
Keywords: Healthcare, Healthcare Professionals, Migration, Psychological Factors.
Actualización sobre los factores de riesgo en linfedema secundario a cáncer: transformando mitos
Authors: Rodriguez Mojica Yudi Milena , Suárez  Moya Ángela
Published: December 2024

El linfedema relacionado con el cáncer (LRC) se define como la acumulación de linfa a consecuencia de un daño en el sistema linfático. Esta condición tiene una incidencia variable, probablemente debido, por un lado, a su latencia prolongada que requiere un seguimiento minucioso a largo plazo y, por el otro, a la falta de definiciones uniformes utilizadas por los médicos para su diagnóstico. Sin embargo, se ha establecido que existen algunos factores de riesgo prevalentes, tales como la presencia de obesidad, la radioterapia y los tratamientos quirúrgicos que involucran la disección o extirpación de ganglios linfáticos, los cuales tienen una asociación directa con el desarrollo del linfedema. En oposición, la extracción de sangre ipsilateral, las inyecciones, las lecturas de la presión arterial, la movilidad de la extremidad y los viajes en avión no están asociados con aumento del linfedema. La evidencia expresada en este artículo puede ayudar a educar a los médicos y pacientes sobre los factores de riesgo para el desarrollo de LRC, lo cual promueve que se abandonen recomendaciones sobrevaloradas que pueden llevar a conductas con mayor riesgo.
Los retos de la rehabilitación oncológica en Colombia y Latinoamérica
Authors: Ritter Paola
Published: December 2024

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Histopathological and Molecular study of effects of potassium dichromate on testis of the adult male mice
Authors: Shaker Ali Nuha
Published: December 2024

Background: Potassium Dichromate is an inorganic chemical used in industrial applications and the laboratory. Potassium Dichromate is harmful to body health. Potassium Dichromate is red-orange in colour and is solid in composition. The current study aims to determine the histological changes in the testes and determine the gene expression for Spef2 (sperm flagellar 2) and Catsper1 (cation channel, sperm associated 1) in mice due to the administration of Potassium Dichromate.
Methods: Twenty adult white male mice with (20-30) grams in weight, (16) weeks in age were divided into double groups, each one have ten mice. G1 administrated potassium dichromate (67) Mg/kg/BW for 21 days orally, while G2 is control group that is administrated PBs. After finishing the administration period, all the animals are sacrificed. The first parts of the testes are kept in formalin 10% to make the histopathological examination. In contrast, the second part of the testes are kept in TRIzol for RNA Extraction to determine the gene expression.
Result: The histopathological examination of G1 showed the destroyed seminiferous tubules in the testis, loss of spermatid, and necrosis. Moreover, the testis shows severely distracted seminiferous tubules and vacuolation of the seminiferous epithelium. No spermatogonia cell can be distinguished, but Leydig cells can be seen. Also, there are primary spermatocytes with necrotic seminiferous tubules. The control group (G2) demonstrated that testis has normal seminiferous tubules with seminiferous tubules filled with spermatids, normal Leydig cells, normal spermatogonia, normal primary spermatocytes, normal spermatid, and normal spermatozoa, with normal epididymis. Moreover, the study found that gene expression of Spef2 and Catsper1 genes was increased in the group that administrated potassium dichromate compared to the control group.
Conclusion: The current work found that potassium dichromate causes histopathological changes in the testis and increases the gene expression of f Spef2 and Catsper1 genes related to sperm activity in mice.
Determination of the aerodynamic coefficients of wind load for spatial trusses made of tubular profiles
Authors: Telemakov Maxim , Buzalo Nina
Published: December 2024

This paper presents new formulas for calculating the aerodynamic drag coefficient of lattice structures, which depend on factors such as surface roughness, Reynolds number, and the geometry of the structure. A nonlinear regression method based on logarithmic transformation of the raw data is proposed for determining the shading coefficient. Comparison of the computed results with the normative values given in SP 20.13330.2016 demonstrated that the proposed formulas can be effectively used to calculate the shading coefficient for spatial trusses with tubular profiles at Reynolds numbers below 4·105, without the need to refer to the charts provided in Appendix B of the standard.
Life cycle requirement time optimization of a construction project
Authors: Zhdanova Mariya , Lapidus Azariy
Published: December 2024

Due to the fact that currently there are no regulated stages of the life cycle of the construction project, in the article we propose a model of 3 stages: pre-design, design and execution stage of construction-installation works. Each of the stages is considered step by step, identified reasons that may affect the time of completion. The importance of linkages between project life cycle stages is noted: reducing the time gap between phases and working in parallel on different phases affect project completion times and costs. Planning and project management allows to optimize work.
Efek Pemberian Antibiotik Kombinasi Spektinomisin dan Linkomisin Selama Satu dan Dua Minggu terhadap Hematologi Broiler
Authors: Wibisono Cahyo , Wijayanti Agustina Dwi , Fadilla Mirza Nur
Published: December 2024

Pemberian antibiotik sebagai salah satu upaya terapi maupun pencegahan penyakit bakterial pada ayam tentu sangat penting mengingat broiler rentan terhadap penyakit. Salah satu antibiotik yang digunakan di Indonesia adalah kombinasi spektinomisin dan linkomisin. Status kesehatan ayam dapat diketahui melalui kondisi hematologinya. Tujuan penelitian ini untuk mengetahui kondisi hematologi berupa kadar hemoglobin, nilai hematokrit, total eritrosit, dan total leukosit pada broiler yang diberikan antibiotik kombinasi spektinomisin dan linkomisin selama satu dan dua minggu. Penelitian menggunakan 40 ekor Day Old Chicken (DOC) broiler yang terbagi dalam 3 perlakuan yaitu kelompok K (kontrol), kelompok A1 (pemberian antibiotik 1 minggu), dan kelompok A2 (pemberian antibiotik 2 minggu). Antibiotik kombinasi spektinomisin dan linkomisin diberikan secara oral lewat air minum dengan menggunakan dosis terapi sebesar 1,5 gram/ 2 liter mulai hari ke-18 sampai hari ke-24 untuk kelompok A1 dan untuk A2 dilanjutkan sampai hari ke-31. Pengambilan sampel darah dilakukan pada hari ke-32 untuk kelompok A1 dan hari ke-39 untuk kelompok A2 melalui vena brakialis. Sampel digunakan untuk mengukur kadar hemoglobin dengan spektrofotometer, nilai hematokrit dengan hematokrit scale reader, jumlah eritrosit dengan pipet thoma eritrosit “101”, jumlah leukosit dengan pipet eritrosit “11”. Data yang diperoleh dianalisis secara deskriptif dan statistik. Hasil penelitian menunjukkan kadar hemoglobin, nilai hematokrit, jumlah eritrosit, dan jumlah leukosit tidak ada perbedaan signifikan (p > 0,05). Kesimpulan dari pemberian antibiotik kombinasi spektinomisin dan linkomisin selama 1 dan 2 minggu tidak berpengaruh terhadap hematologi broiler.
EXPANDING THE SCOPE OF APPLICATION OF CLINICAL BIOCHEMICAL REAGENT KITS FOR DETERMINING METABOLITE CONCENTRATIONS AND ENZYME ACTIVITIES AND OPTIMIZING PROTOCOLS OF THEIR USING
Authors: Malygina N. M. , Lianguzov A. Y. , Petrova T. A. , Ivanov A. M.
Published: December 2024

Introduction. The main consumers of commercial reagent kits for the study of metabolites and enzymes are clinical laboratories. Therefore, protocols for their using and calculating indices were developed mainly for blood and urine analysis. However, it is regularly necessary to determine metabolites concentration and enzymes activity to solve other tasks. Purpose of the work – as a case study estimation of glucose concentration and amylase activity in hemolymph plasma of the gastropod mollusc Achatina fulica to demonstrate how protocols for using some clinical reagent kits for determining metabolites concentration and enzymes activity can be optimized and how the scope of their application can be expanded. Material and Methods. The hemolymph plasma of the gastropod mollusc A. fulica served as the object of the study. Glucose concentration and amylase activity were determined in hemolymph plasma using clinical biochemical reagent kits from Spinreact (Spain). The standard and optimized protocols for determining glucose concentration are described. An optimized protocol for determining amylase activity has been described previously. Results. A. fulica is often used as a convenient model in experimental and practical developments of different areas of focus. The knowledge of diagnostically significant biochemical indices of hemolymph plasma of mollusks makes it possible to monitor the "state of health" of animals during their cultivation in laboratories and practical using. In contrast to the original protocol for determining glucose concentration, full calibration experiments were performed, with sample analysis time reduced to one minute. The optimized protocols for using reagent kits proposed in the article were tested to determine glucose concentration and amylase activity in the hemolymph plasma of A. fulica (n=16). The values were 0,42 ± 0,07 mM and 27,8 ± 0,6 IU/L, respectively. Conclusion. As a case study estimation of glucose concentration and amylase activity in hemolymph plasma of the gastropod mollusc Achatina fulica the effectiveness of the proposed ways of optimization of protocols for using some clinical reagent kits was demonstrated. The optimized protocols are suitable for determining the concentration of such metabolites as glucose and lactate as well as for analyzing the kinetics of various enzymes with direct measurements of their activity. The performed optimization allowed to expand the scope of application of biochemical reagent kits used in medicine, as well as to significantly reduce the time of analysis.
EVALUATION OF BIOCOMPATIBILITY AND ADHESIVE PROPERTIES OF SCAFFOLDS BASED ON INORGANIC BONE MATRIX
Authors: Litvinov Y.Y. , Kabanov D.S. , Krasnov V.V.
Published: December 2024

Introduction. The use of cellular engineering structures, including cell cultures and composite biomaterials, ensures maximum efficiency of bone de-fect repair, and the development of techniques and testing of carriers for osteogenic cell transplantation remains an urgent task of modern science. The study carried out biological testing of scaffolds based on the inorganic bone matrix obtained by a previously developed and patented method at the Institute of Medicinal and Aromatic Plants using human fibroblasts in terms of cytotoxicity, efficiency of cell adhesion and proliferation. The purpose of the study is to evaluate experimentally the biocompatibility and adhesive properties of SIBM samples using human cell cultures in vitro to create an implantation cellular engineering structures. Material and methods. The object of the study is SIBM samples of the inorganic bone tissue of the compact substance of the diaphysis of the fe-mur of a bull with a cell line of human dermal fibroblasts HdFb (d77). The biocompatibility and adhesive properties of SIBM with respect to the cell line of dermal fibroblasts, their effect on cell viability and proliferative activity were studied using phase contrast microscopy, scanning electron microsco-py, and the classical spectral method using tetrazolium yellow salt (MTT method). Results. The formation of contacts of the plasma membrane of dermal fibroblasts with the SIBM samples was studied within 240 hours of incubation. At the same time, there were no significant changes in cell morphology. They formed a confluent monolayer (with cells tightly adjacent to each other), adhered well and were distributed over the surface of the SIBM. SIBM samples had virtually no effect on the metabolic activity of HdFb cells. The data obtained indicate a minimal effect of the studied samples on cell viability and proliferation, the absence of toxicity to cells and good biocompatibility with dermal fibroblasts in vitro. Conclusions. It has been experimentally proved that the studied SIBM samples obtained by the previously developed method at the Institute of Me-dicinal and Aromatic Plants have adhesive properties, lack of cytotoxicity with respect to human HdFb dermal fibroblasts and have little effect on their proliferation in vitro.
A RETROSPECTIVE ANALYSIS OF THE EXPERIMENTAL AND CLINICAL STUDY OF THE ANTIVIRAL HERBAL DRUG FLAKOZID IN VIRAL INFECTIONS CHARACTERIZED BY LESIONS OF THE SKIN AND MUCOUS MEMBRANES
Authors: Karabaeva V.V. , Krepkova L.V. , Babenko A.N. , Mizina P.G. , Shutkina S.M.
Published: December 2024

Introdction. Herpesvirus infections are one of the leading medical and social problems and are defined as a "global problem of humanity". Currently, the most common are simple (HSV-1, HSV-2) and herpes zoster (VVO). For the prevention and treatment of herpesvirus infections, antiviral drugs are prescribed, one of which is the herbal drug Flakozid, 0.1 g tablets for oral administration. The aim of the work was a retrospective analysis of the results of an experimental and clinical study of Flakozid in simple recurrent and herpes zos-ter, chickenpox. Material and methods. The antiviral properties of Flakozid were studied in in vitro experiments, in the culture of chicken embryo fibroblast cells against three strains of herpes virus (2 strains geratogenic "10", "90" and dermatogenic strain "64") and in vivo − on a model of experimental herpetic encephalitis of white mice in doses from 20 mg/kg to 500 mg/ kg with the administration of per os and subcutis. The results of the clinical study of Flakozid were analyzed in 313 patients (adults and children) with simple recurrent herpes 202 patients, including genital – 65, with herpes zoster – 45, chickenpox – 66. The criteria for the effectiveness of antiviral therapy of herpes were the duration of inflammatory phenomena, a reduction in the number and duration of relapses; in chickenpox – the severity of symptoms of intoxication, the nature and spread of rashes, the degree of their re-verse development. Flakozid was prescribed 0.2–0.6 g per day. Results. Experimental studies have shown that Flakozid had a high viral inhibitory effect against Herpes simplex. Treatment with Flakozid led to a high therapeutic effect: complete resolution of rashes in simple recurrent herpes after an average of 6-14 days, genital – 8-15 days, shingles – 7-15 days and shortening the duration of relapses by 2 times. The therapeutic effect of Flakozid in the treatment of genital herpes was noted in 91.6% of cases and exceeded the effect of Alpizarin (40%); in chickenpox –74%. Conclusions. The high therapeutic effect of Flakozid in the treatment of viral infectious and inflammatory dermatoses in adults and children allowed it to be recommended in a wide clinical practice in the treatment of simple recurrent herpes, including genital and extragenital localization; herpes zoster, chickenpox.
PELATIHAN OPTIMALISASI PENGGUNAAN KIT PRAKTIKUM IPA UNTUK GURU SDN SUNGAI MIAI 5 DAN SDN SUNGAI MIAI 7 BANJARMASIN
Authors: Arifuddin Muhammad , Mahardika Andi Ichsan , Mastuang  , Azhari Andy , Munawaroh Devi , Syifa Linda Nur
Published: December 2024

Percobaan atau praktikum merupakan bagian hal yang penting dalam  pembelajaran IPA disebabkan karena didasarkan pada penemuan berdasarkan gejala-gejala fisis pada kehidupan sehari-hari. Namun metode pembelajaran pada mata pelajaran IPA guru didominasi dengan ceramah dan diskusi, masih jarang melakukan kegiatan pembelajaran yang berbasis saintifik dengan metode praktikum ataupun demonstrasi. Kegiatan pengabdian masyarakat ini bertujuan untuk melatihkan guru-guru mengoptimalkan penggunaan KIT praktukum IPA pada pembelajaran IPA di SD. Pengadian dilaksanakan di SD Negeri Sungai Miai 5 Banjarmasin dengan jumlah peserta 20 orang guru sekolah dasar. Palatihan dilakukan dengan melatihkan guru-guru melakukan sejumlah percobaan IPA menggunakan KIT Praktikum IPA secara berkelompok yang dibimbing oleh tim PKM dari FKIP Universitas Lambung Mangkurat. Berdasarkan hasil Pelatihan Penggunaan KIT Praktikum IPA untuk Guru SD diperoleh simpulan bahwa pelatihan dapat meningkatkan pemahaman guru dan kemampuan guru menggunakan KIT Praktikum IPA dengan berperan aktif dalam mendengarkan penjelasan tim PKM dan melaksanakan kegiatan praktikum IPA menggunakan KIT IPA.
PELATIHAN PENELITIAN PENDIDIKAN DAN PEMBELAJARAN UNTUK GURU, KARYAWAN, DAN PENELITI PEMULA
Authors: Farhan Muhamad , Arif Rahman Hakim  , M. Tohimin Apriyanto  , Napis
Published: December 2024

Dinamika nyata yang terjadi dalam bidang pendidikan secara umum masih harus dilakukan perbaikan pada salah satu aspek Standar Nasional Pendidikan, yaitu standar proses pembelajaran termasuk di dalamnya berupa pemilihan media, pemilihan metode, kemampuan awal sebelum proses pembelajaran dilakukan dan lain-lain yang semisal. Permasalahan tersebut menjadi fokus Tim Pengabdian kepada Masyarakat (PkM) untuk menawarkan solusi kepada Annadif Bimbel (Lembaga Bimbingan & Konsultasi Belajar) untuk melakukan pelatihan, bimbingan, dan pendampingan mengenai teori dan praktik penelitian pendidikan dan pembelajaran. Kegiatan pelatihan penelitian pendidikan dan pembelajaran untuk guru, karyawan, dan peneliti pemula ini dilaksanakan di aula Annadif Bimbel yang diikuti oleh 25 orang peserta. Rangkaian kegiatan dalam pelatihan ini yaitu: (1) Tahap persiapan; (2) Tahap pemaparan mengenai deskripsi kegiatan; (3) Tahap penyampaian materi tentang penelitian pendidikan dan pembelajaran; (4) Tahap latihan terbimbing, (5) Tahap diskusi. Pelatihan penelitian pendidikan dan pembelajaran untuk guru, karyawan, dan peneliti pemula yang sudah dilaksanakan ini sangat bermanfaat bagi semua peserta, sehingga mampu meningkatkan kompetensi para peserta dalam hal melakukan penelitian. Secara keseluruhan kegiatan PkM ini dapat disimpulkan sudah terlaksana dengan baik dan menghasilkan dampak yang positif dari Tim Pelaksana ke lembaga mitra kegiatan
Pemanfaatan Sampah Plastik Menjadi Ecobrick Sebagai Upaya Mengurangi Sampah Plastik di Desa Pringgabaya Kecamatan Pringgabaya Kabupaten Lombok Timur
Authors: Suciati Erima , Permatasari Baiq Intan , Muhlas Muhammad , Lestari Nunung Dewi , Putri Mira Suaniarti , Sasmitha Yuan , Aji Reza purnama , Nurhidayat Iqbal Febri , Yulianto Angga Pratama , Izmi Uliatun
Published: December 2024

Sampah merupakan salah satu masalah yang terdapat di Indonesia, sampah sangat erat kaitannya dengan pertumbuhan penduduk. Berdasarkan data BPS, Kabupaten Lombok Timur memiliki penduduk paling banyak di Provinsi NTB, yaitu 1.345.605 jiwa pada 2021. Permasalahan pengelolaan sampah plastik hingga sekarang belum dapat terselesaikan dengan baik. Salah satu solusi yang dapat di gunakan untuk pengelolaan sampah plastik adalah dengan metode ecobrickPelaksanaan program kerja pengabdian masyarakat ini dilaksanakan pada tanggal 9 januari 2023 di kantor desa dan musholla Pringgabaya, dengan beberapa tahapan yaitu tahap persiapan dan tahap pelaksanaan. Tahap awal yang telah dilakukan adalah melakukan diskusi dengan tokoh masyarakat setempat yaitu kepala dusun. Tahap pelaksanaan meliputi sosialisasi, penyuluhan, dan pelatihan. Kegiatan pengabdian masyarakat dengan judul Sosialisasi dan Pelatihan Pemanfaatan Sampah Plastik Menjadi Ecobrick Sebagai Upaya Mengurangi Sampah Plastik di Desa Pringgabaya Kecamatan Pringgabaya Kabupaten Lombok Timur dilaksanakan dengan baik sesuai dengan yang direncanakan dalam setiap tahapannya yaitu dimulai dari tahap persiapan hingga pelaksanaan. Warga desa Pringgabaya menyambut dengan baik dan antusias dari kegiatan sosialisasi atau penyuluhan sampai pelatihan pembuatan ecobrick.Masyarakat teredukasi dan memahami akan bahaya sampah plastik, dan memahami metode ecobrick dapat mengurangi sampah plastik dan masyarakat mengetahui cara membuat produk ecobrick secara mandiri dan dapat dikembangkan menjadi produk yang ekonomis kegiatan ini salah satu contoh produk yang dibuat adalah meja.
A BELA E A FERA, VÍTIMA E AGRESSOR: UM RETRATO DA SÍNDROME DE ESTOCOLMO NO CONTO A BELA E A FERA
Authors: Sobrinho Ana Paula da Silva , Maceno Regilane Barbosa
Published: December 2024

O conto de fadas A Bela e a Fera transporta as crianças para um mundo envolvido por magia e acontecimentos fantásticos, mas que nas raízes da sua origem se pode perceber elementos mais complexos do que uma simples história para dormir, podendo se transformar em investigação psicológica e crítica social sobre a condição a qual a protagonista Bela é submetida pelo antagonista Fera. Portanto, o presente artigo tem como objetivo principal relacionar as características e condições que permeiam a Síndrome de Estocolmo neste conto, evidenciando a condição de vítima de Bela durante sua jornada como heroína e a Fera como seu agressor e responsável por a colocar em uma situação de medo e desregrado no decorrer da trama. Análise que será feita por meio de materiais teóricos construídos por mentes como Graham (1994), Gómez (1999), Trindade (2010), Hueck (2023) e outros que se encontram no corpo deste trabalho.
Palavras-chave: A Bela e a Fera; Síndrome de Estocolmo; vínculo; vítima.
LETRAMENTO DIGITAL NA BNCC: CAMINHOS PARA A EDUCAÇÃO DO SÉCULO XXI
Authors: Oliveira Rauenas Silva , Motta Cláudia Maria Magalhães
Published: December 2024

O artigo analisa a integração do letramento digital ao ensino básico no Brasil por meio da Base Nacional Comum Curricular (BNCC), aprovada em 2018. O objetivo principal é discutir como a BNCC promove o uso das Tecnologias Digitais de Informação e Comunicação (TDICs) para tornar a educação mais inclusiva, crítica e conectada às demandas contemporâneas. Utilizando pesquisa documental, o texto examina as competências gerais da BNCC e os desafios estruturais, como desigualdades de acesso à tecnologia e formação contínua de professores. Os autores referenciam teóricos como Dionísio (2011), para discutir multimodalidade e letramentos; Dudeney, Hockly e Pegrum (2015), sobre letramento digital; e Oliveira (2009), abordando a relação entre tecnologia e formação docente. A análise destaca a necessidade de políticas públicas voltadas para infraestrutura e capacitação docente como essenciais para a efetivação das diretrizes da BNCC e o fortalecimento de práticas pedagógicas alinhadas ao contexto digital.
Palavras-chave: BNCC; educação digital; letramento; tecnologia na educação; TDICs.
PENÉLOPE E MEDEIA NO CONTO DUAS MARGENS
Authors: Ribeiro Francigelda
Published: December 2024

Este artigo apresenta uma análise do conto Duas margens, de Rinaldo de Fernandes, publicado no livro Contos cruéis. No processo analítico, duas figuras míticas, Penélope e Medeia, são tomadas como parâmetros para refletir acerca do posicionamento das personagens que figuram como centro da narrativa.
Palavras-chave: Conto. Luz e sombra. Medeia e Penélope.
EDUCAÇÃO EM SAÚDE SOBRE EXPOSIÇÃO SOLAR PROLONGADA E DESPROTEGIDA EM UMA UNIDADE MUNICIPAL DE SAÚDE: UM RELATO DE EXPERIÊNCIA
Authors: Silva Alice Góes Félix da , Correa Carlos Rafael da Costa , Rufino Fernanda da Costa , Tavares Glaucia Ferreira , Dias Biatriz Araújo Cardoso , Dias George Alberto da Silva
Published: December 2024

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EDUCAÇÃO EM SAÚDE PARA ESTIMULAÇÃO DA FUNÇÃO MOTORA GROSSA EM CRIANÇAS DO ENSINO FUNDAMENTAL: RELATO DE EXPERIÊNCIA
Authors: Vilhena Thalyta Karollyna Costa , Dias Gabriel Pelais , Chaves Yasmim Vitória da Silva , Paz Rubens Marinho da , Dias Biatriz Araújo Cardoso , Dias George Alberto da Silva
Published: December 2024

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EDUCAÇÃO EM SAÚDE PARA O ENVELHECIMENTO NEUROLÓGICO VINCULADO AO DECLÍNIO COGNITIVO E FUNCIONAL EM IDOSOS: RELATO DE EXPERIÊNCIA
Authors: Gomes Ananda Beatriz Lobato , Bittencourt Beatriz Oliveira , Luz Dhuliana Tayna Faro da , Alves Luciana da Silva , Dias Biatriz Araújo Cardoso , Dias George Alberto da Silva
Published: December 2024

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EMERGÊNCIAS PSIQUIÁTRICAS: A IMPORTÂNCIA DO PROCEDIMENTO ADEQUADO PARA A CONTENÇÃO SEGURA DOS PACIENTES
Authors: Batista Beatriz Tavares , Oliveira Walace Coelho de , Moreira Edinaldo Benedito Sousa , Castro Elaine do Socorro Gonzaga de , Silva Fernanda Nogueira , Brito Ryan Daniel Gomes , Miranda Suziane Lopes , Ribeiro Andreia Costa
Published: December 2024

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CAPACITAÇÃO PRÁTICA EM ATENDIMENTO AO POLITRAUMATIZADO PARA ESTUDANTES DO INTERIOR DO PARÁ: EXPERIÊNCIA COM TÉCNICAS DE ROLAMENTO, PRANCHAMENTO E IMOBILIZAÇÃO
Authors: Carmo Jhennifer Oliveira do , Moraes Manelson Pinheiro , Souza Lelison Leite de , Silva Karyma Tinaia Brito e , Araújo Acza Keury Viana , Ávila Clarise Quaresma de , Duarte Naira Sousa
Published: December 2024

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MODELING BUSINESS PROCESSES OF MAKING FINANCIAL DECISIONS USING DIGITAL TECHNOLOGIES
Authors:   Simon Kuznets Kharkiv National University of Economics, Aleksieienko Inna , Leliuk Svitlana ,   Simon Kuznets Kharkiv National University of Economics
Published: December 2024

The study presents the results of modeling business processes related to making financial decisions. A structural-functional model for assessing the investment attractiveness of the enterprise was built, which takes into account the turbulent surrounding conditions of its operation. This made it possible to formalize the information flows necessary for the development of investment measures. The requirements for information support for the analysis of the financial condition of the economic entity are presented. The results of the formation of the data array for the implementation of analytical procedures and the subsequent construction of visualizations based on their results are presented. The structure of the data for the formation of information support for making management decisions is visualized. An analitical dashboard was formed as a basis for making management decisions regarding investments.
COMPLIANCE MANAGEMENT SYSTEM: FEATURES OF FORMATION AND DEVELOPMENT
Authors:   Kyiv National Economic University named after Vadym Hetman, Ovsiienko Olha
Published: December 2024

The historical evolution of compliance management system is analyzed. Controversial principles that form the basis of modern compliance management models have been identified and disclosed. These include: endogeneity – exogeneity; reactivity – proactivity; functionality – process approach; isomorphism – flexibility. The components of compliance management are systematized and directions for their adaptation to the needs of the organization are considered. The role of compliance institutionalization in the division of responsibility between the organization and employees is revealed. Current trends in the development of compliance management have been identified, such as the initiation of compliance as a tool for implementing ESG principles; adherence to international compliance management standards; digitization, and the use of artificial intelligence. It is proven that these trends increase the endogeneity and isomorphism of the compliance management system, which may reduce its effectiveness due to excessive control, the likelihood of biased decision-making, and weak adaptation to the organization's needs.
Translation Report: An Analysis on the Chinese-English Translation of Porcelain Culture Texts of Selected Excerpts from The Civilizations in China
Authors: Hong Jingqi
Published: December 2024

This report focuses on the translation of the chapters on the “Preface, Chapter One: Bluish White China and Chapter Three: The Blue and White China" from the book “The Civilizations in China" exploring in-depth the translation strategies of porcelain culture in Jingdezhen, China. With its distinct characteristics and profound connotations, porcelain culture occupies an essential position in the treasure trove of Chinese culture. This report aims to present this unique cultural heritage to the international academic community through precise translation, facilitating cultural exchanges and mutual learning between China and the West. During the translation process, this report fully considers the particularities of cultural popular science texts and the cognitive backgrounds and reading expectations of international readers. This approach aims to make the translation more aligned with the language and cultural habits of the target audience. This report not only delves into the challenges and difficulties encountered in translating domestic ethnic cultural texts but also proposes a series of innovative and practical translation solutions. These strategies and methods are designed to convey the cultural essence of the original text to the fullest extent, promoting deep cultural exchanges and integration between China and the West. Through this translation practice, the report aspires to provide valuable academic references for the translation of domestic porcelain cultural texts and contribute academic strength to promoting porcelain culture of Jingdezhen in Chian worldwide.
Prefixed Nouns and Verbs in Arabic: Evidence for Dual-route Processing in Auditory Word Recognition
Authors: Aljasser Faisal
Published: December 2024

The process of accessing and retrieving the morphological components of complex words during word recognition has led to the development of various models that explain morphological representation and processing. This area of research is particularly significant in the context of Arabic, where it has been suggested that lexical processing predominantly relies on root-based obligatory morphological decomposition, as opposed to stem-based processing. To investigate this proposal, we conducted an experiment focusing on morphologically complex prefixed words. These words were carefully matched for surface and stem frequencies, allowing us to isolate the variable of root type frequency, or family size, to observe its specific effects. We analyzed the impact of root type frequency on response times for lexical decisions concerning spoken prefixed nouns and verbs in Arabic. Our findings revealed that response times for lexical decisions were significantly influenced by root type frequency, but only for prefixed nouns. This suggests that the proposed model of root-based obligatory morphological decomposition may not be universally applicable to all types of prefixed words in Arabic. Instead, these results indicate a need for a more nuanced understanding of morphological processing, supporting dual-mechanism approaches over single-mechanism theories. This research contributes to the ongoing discourse on morphological processing in language, particularly highlighting the complexities involved in recognizing morphologically rich languages like Arabic.
Understanding the shapers of sustainability in small businesses
Authors: Albert Gomes
Published: December 2024

Sustainability in small businesses has become an essential focus for fostering long-term economic, social, and environmental benefits. This study explores the key internal and external factors that influence sustainability in small enterprises, emphasizing the role of leadership, organizational culture, financial resources, and external market dynamics. Using a qualitative approach, the research analyzes data from interviews with small business owners and managers in Dhaka, representing diverse sectors such as food services, retail, construction, software, and packaging. Findings highlight the significance of prior professional or entrepreneurial experience of an entrepreneur, employee retention, market adaptation, and personal networks in achieving sustainability. Challenges such as resource constraints, regulatory changes, and limited innovation capacity were identified, alongside strategies including vertical integration, customer engagement, and leveraging prior knowledge to mitigate these barriers. The study contributes to the limited literature on small business sustainability by offering actionable insights for practitioners and policymakers to support sustainable practices in small enterprises.
The effect of supplementary feeding (PMT)-child recovery intervention in the coastal area of North Buton Regency, Southeast Sulawesi Province
Authors: Wa Ode Salma  , Asniah  , Aisnah  , Adibin  , Mirnawati
Published: December 2024

Background: Malnutrition in Coastal Areas is still a public health problem in low- and lower-middle-income countries (LMICs). Nutritional status plays an important role in supporting growth, physical and cognitive development according to the child's age. The purpose of this study is to analyze the effect of Supplementary Feeding Recovery (PMT-P) on children's nutritional status.
Methods: Experimental research design with Pretest and Posttest One Group Design approach. Involving 75 mothers who have children aged 6-24 months in the work area of the North Buton Regency Health Office, the child sample was selected by purposive sampling with inclusion criteria such as children who have growth below the red line (BGM) or experience very thin nutrition, toddlers who consume PMT-P from the government program in the form of biscuits, given regularly for up to 90 days. Children aged 6-11 months are given 80 gr/day equivalent to 8 pieces of biscuits (2 packs) while children aged 12-24 months are given 120 gr/day equivalent to 12 pieces of biscuits (3 packs). The instruments used in this study were the Healthy Towards Card (KMS) and the measurement of the toddler's weight was carried out using a Msumed brand digital scale with an accuracy of 0.1 cm while the measurement of the body length and height of the toddler was carried out using an Msumed brand infantometer and a statuemeter with an accuracy of 0.1 cm. The data was analyzed using a paired t-test (significant p<0.005).
Results: The results showed that there was an effect of PMT-P administration before and after the intervention for 3 months on the nutritional status of children (p = value 0.000).
Conclusion: There is an effect of giving PMT-P before and after the intervention for 3 months on the nutritional status of children. Therefore, the Government must continue to increase PMT-P as an alternative in management of malnutrition in children aged 6 to 24 months in North Buton Regency, southeast Sulawesi Province, Indonesia
Peranan Zakat Mal Pengusaha Ayam Petelur dalam Peningkatan Ekonomi Masyarakat di Jorong Limau Puruik Nagari Limau Purut Kecamatan Kinali
Authors: Sonia Astuti  , Fawza Rahmat  , Maisarah Leli
Published: December 2024

This research was conducted in Jorong Limau Puruik, Nagari Limau Purut, Kinali District, with a focus on the role of zakat mal from layer chicken entrepreneurs in improving the community's economy. The formulation of the problem includes the role of zakat mal, the calculation of zakat mal, and the distribution of zakat mal from layer chicken entrepreneurs. This research aims to explain the contribution of zakat in improving the community's economy, calculation methods, and zakat distribution mechanisms. This research uses descriptive qualitative method with field approach. Data were obtained through interviews with zakat recipients (mustahiq), business owners, and laying hen farm employees. Primary data is supported by secondary data from the Limau Purut Nagari Wali Office. The results showed that zakat on laying hens has a significant role in improving the community's economy, both consumptively and productively. Consumptive improvements include the fulfillment of daily needs, education costs, and business capital. Meanwhile, productive improvement occurs when zakat is used as capital for small businesses that develop and have a positive impact on the economy. The calculation of zakat is analogous to trading commodities, with a rate of 2.5% without using the nisab of 85 grams of pure gold, and is paid after haul (one year). Zakat is distributed to mustahiq who are entitled to receive.
Strategi Peningkatan Daya Saing UMKM Pengolahan Bandeng di Desa Jarangan, Kecamatan Rejoso (Menggunakan Analisis SWOT)
Authors: Muh. Bagus Wijaya  , Nurul Lathifah
Published: December 2024

The development of milkfish processing businesses in Jarangan Village, Rejoso District has great potential due to the abundance of raw materials and the skills of the community. However, challenges such as limited capital, market access, and human resources still hinder progress. Through a SWOT analysis, a development strategy was formulated that includes skills training, increased access to capital, product diversification, and the utilization of digital technology for marketing. Support from the government and collaboration among business actors are crucial to optimizing this potential. With the right strategic measures, it is hoped that the processing of milkfish in Jarangan Village can significantly contribute to local economic growth and improve the welfare of the community.
Sejarah Pemikiran Ekonomi Islam pada Masa Rasulullah SAW dan pada Masa Khulafaur Rasyidin Beserta Perbedaannya
Authors: Perwira Hasibuan  , Mhd. Rifq Alfahrezi  , Ahmad Wahyudi Zein  , Ilhamuddin Sianifar
Published: December 2024

Islamic economic thought has strong roots since the time of the Prophet PBUH and developed further during the time of Khulafaur Rashidin. This journal aims to analyze the differences in economic thinking and policies in the two periods. During the time of the Prophet, the main focus was to build an economic system based on sharia values such as justice, the prohibition of usury, and the implementation of zakat to create social solidarity. On the other hand, the Khulafaur Rasyidin period presented more complex challenges, such as the management of large areas, the distribution of wealth, and political stability. In this article, we discuss the economic policies of the caliphs in detail, including the formation of diwans, land management, and supervision of state financial administration. The study shows that the core values of Islamic economics remain consistent, but their implementation adapts to social, political, and economic dynamics. This research is expected to provide new insights into re...
Strategi Pengelolaan Persediaan UMKM (MCREPES di Surabaya) Agar Tetap Kompetitif di Pasar
Authors: Lea Berliana Jeni Salih  , Sri Rahayuningsih
Published: December 2024

One of the key components of success for small and medium enterprises (SMEs), including crepes businesses, is inventory management. This article discusses effective inventory management strategies to enhance operational efficiency and competitiveness of crepes SMEs in the market. Some of the methods discussed include the Just in Time (JIT) method to minimize raw material waste, demand forecasting based on sales data, and leveraging digital technology such as inventory applications to monitor stock in real time. Another strategy highlighted is the ABC classification method to categorize raw materials based on value and priority levels, establishing safety stock to anticipate uncertainties, and fostering collaboration with suppliers to ensure the availability of high-quality raw materials. By implementing these strategies, crepes SMEs are expected to manage their inventory more efficiently, reduce the risk of stock shortages or overstocking, and remain competitive in an increasingly challenging market.