bluuebunny/crossref_metadata_2025 huggingface dataset:
Drying characteristics and quality of taegeuk ginseng (Panax ginseng C.A. Meyer) using far‐infrared rays
Authors: Ning Xiaofeng , Han Chungsu
Published: November 2012

The purpose of this study is to investigate the drying characteristics of taegeuk ginseng using a far‐infrared dryer. The dryer used for this experiment can control the drying parameters such as far‐infrared heater temperature and air velocity. The far‐infrared drying tests of taegeuk ginseng were performed using large, medium and small ginseng at an air velocity of 0.6 m s−1, and drying chamber temperatures of 45, 55 and 65 °C. The results were compared with those of the hot‐air drying method. The drying characteristics were analysed based on factors such as drying rate, colour changes, internal tissue structure of ginseng, saponin contents and antioxidant activities, and energy consumption. In general, the hot‐air drying time was 3–3.5 days longer than that of far‐infrared drying under the same conditions. The colour changes of far‐infrared drying were also smaller than that of hot‐air drying. Far‐infrared dryer required less energy consumption about 9.67–14.8% less than that required by hot‐air drying. At the same time, the saponin and polyphenol contents of taegeuk ginseng subjected to far‐infrared drying were 1.01 mg g−1, 7.81 mg/100 g higher than that subjected to hot‐air drying, respectively. The results showed that the far‐infrared drying increases the capacity and quality of taegeuk ginseng.
Creating patches of native flowers facilitates crop pollination in large agricultural fields: mango as a case study
Authors: Carvalheiro Luísa G. , Seymour Colleen L. , Nicolson Susan W. , Veldtman Ruan
Published: November 2012

As cropland increases, fields become progressively isolated from pollinators, leading to declines in pollinator‐dependent crop productivity. With the rise in demand for pollinator‐dependent foods, such productivity losses may accelerate conversion of natural areas to cropland. Pollination–compensation measures involving managed pollinators or hand pollination are not always optimal or are too costly. Introducing areas of native vegetation within cropland has been proposed as a way to supplement crop pollinators, but this measure is perceived by farmers to carry costs outweighing benefits to agricultural production. Studies quantifying benefits of small patches of native flowers to crop pollination are therefore necessary to encourage such practices.

To ascertain whether provision of floral resources within farmlands can facilitate pollination, and hence, crop yields, small experimental patches of perennial native plants (native flower compensation areas, NFCAs) were created in nonproductive areas of large commercial fields of several cultivars of mango Mangifera indica.

Pesticide use and isolation from natural habitat were associated with declines in flying visitors and in mango production (kg of marketable fresh fruit), but presence of NFCAs ameliorated these declines, and NFCAs did not harbour any mango pests. In areas far from natural vegetation, orchards near NFCAs had significantly higher diversity and abundance of mango flying visitors, as well as mango production, than orchards far from NFCAs, although these measures were still lower than in orchards close to natural areas.

Neither the most abundant flower visitors to mango (ants) nor initial fruit set was significantly affected by distance, pesticides or NFCAs, suggesting that although fertilization is associated with factors unaffected by isolation from natural habitat and pesticide use (i.e. self‐ and ant‐pollination), viable fruit set (and ultimately, production) requires cross‐pollination, for which flying visitors are essential.

Synthesis and applications. Our results show that the presence of small patches of native flowers within large farms can increase pollinator‐dependent crop production if combined with preservation of remaining fragments of natural habitat and judicious use of pesticides. Native flower compensation areas represent a profitable management measure for farmers, increasing cost‐effectiveness of cropland while indirectly contributing to preservation of natural habitat.
Outcrossing rates in two self‐compatible, hybridising Rhinanthus species: implications for hybrid formation
Authors: Ducarme V. , Wesselingh R. A.
Published: November 2012

The congeners Rhinanthus angustifolius and Rhinanthus minor, two annual hemiparasites pollinated by bumblebees, are known to hybridise in the wild. Both species are self‐compatible, but the capacity for autonomous selfing is higher in R. minor. This suggests a difference in realized outcrossing rates, which have not been determined before in these species. Using microsatellites, both species turned out to have mixed mating systems, but with a much lower multilocus outcrossing rate (0.13) for R. minor compared to R. angustifolius (0.76). We hypothesised that a higher outcrossing rate should lead to a higher chance of heterospecific pollination, and we therefore determined the rate of hybrid formation on each species in an artificial mixed population. Hybrid seeds were produced at low frequency (4.5%), and no significant difference was found between the species. It is therefore likely that post‐pollination processes influence hybrid seed formation to counteract the expected difference in heterospecific pollen deposition. We checked fruit set, seed set and the rate of autonomous selfing in controlled crosses in the greenhouse in 2 years, and found that fruit set (2003) or seed set (2010) were lower in R. angustifolius × R. minor crosses relative to the reciprocal cross. Hybrid seeds produced on R. angustifolius also had a much lower germination rate, so most of the established F1 hybrid plants have the R. minor cytoplasm. The formation of advanced hybrids depends on pollinator preference, which is biased towards R. angustifolius if present in sufficient numbers, because it offers more rewards.
Xylem vulnerability to cavitation can be accurately characterised in species with long vessels using a centrifuge method
Authors: Tobin M. F. , Pratt R. B. , Jacobsen A. L. , De Guzman M. E.
Published: November 2012

Vulnerability to cavitation curves describe the decrease in xylem hydraulic conductivity as xylem pressure declines. Several techniques for constructing vulnerability curves use centrifugal force to induce negative xylem pressure in stem or root segments. Centrifuge vulnerability curves constructed for long‐vesselled species have been hypothesised to overestimate xylem vulnerability to cavitation due to increased vulnerability of vessels cut open at stem ends that extend to the middle or entirely through segments. We tested two key predictions of this hypothesis: (i) centrifugation induces greater embolism than dehydration in long‐vesselled species, and (ii) the proportion of open vessels changes centrifuge vulnerability curves. Centrifuge and dehydration vulnerability curves were compared for a long‐ and short‐vesselled species. The effect of open vessels was tested in four species by comparing centrifuge vulnerability curves for stems of two lengths. Centrifuge and dehydration vulnerability curves agreed well for the long‐ and short‐vesselled species. Centrifuge vulnerability curves constructed using two stem lengths were similar. Also, the distribution of embolism along the length of centrifuged stems matched the theoretical pressure profile induced by centrifugation. We conclude that vulnerability to cavitation can be accurately characterised with vulnerability curves constructed using a centrifuge technique, even in long‐vesselled species.
Collective Rights and Personal Freedoms: A Discursive Analysis of Participant Accounts of Authoritarianism
Authors: Gray Debra , Durrheim Kevin
Published: November 2012

This article presents a discursive analysis of participant accounts of authoritarianism, with the aim of understanding how participants construct accounts about authority, when, and for what purposes. Participants completed a 30‐item Right‐Wing Authoritarianism scale and were then interviewed about how they went about this task. Analyses revealed that, despite an overall consistency when answering items on an authoritarianism scale, participants in this study did not consistently choose to produce authoritarian responses in contrast to the nonauthoritarian alternative. Instead, the construction and expression of authoritarian ideas was found to be directly related to two rhetorical features of conversing about authoritarianism: (1) the ideological dilemma of society versus individual and (2) the mobilization of arguments about social and personal threat that allowed participants to construct accounts about collective rights or personal freedoms. These findings are discussed in terms of their implications for current debates about how authoritarianism should be theorized and studied.
British Muslim Political Participation: After Bradford
Authors: AKHTAR PARVEEN
Published: November 2012

In this article I argue that there is a significant generational shift within British Pakistani communities in relation to political participation and civic engagement. Using George Galloway's March 2012 by‐election victory in Bradford West and an analysis of primary empirical research conducted amongst British Pakistani communities between 2005–2007, and, 2011, I argue that kinship‐based bloc voting—a feature of British Pakistani political engagement in UK politics—is being challenged. A younger generation of British Pakistanis want politicians to engage with them as individuals rather than politicians assuming their votes through co‐opting Pakistani community elders in a system of patronage politics, an arrangement which has been in place since mass immigration from the subcontinent in the 1950s and 60s.
Globalisation and Public Language
Authors: CROWCROFT ROBERT
Published: November 2012

This article questions what the concept of ‘globalisation’ really amounts to. In doing so it highlights problems for the ascendancy of globalisation in contemporary public debate. Globalisation has become a catch‐all; the phrase is now used to try and explain all manner of phenomena from everyday life to international politics. But the article suggests that this may be little more than a combination of rhetoric and wishful thinking. It asserts that the contemporary world is being driven by older and familiar pressures, such as state power and nationalism. As a result, the idea of ‘globalisation’ needs to be treated with some scepticism.
Veteran Care in the United Kingdom and the Sustainability of the ‘Military Covenant’
Authors: MUMFORD ANDREW
Published: November 2012

This article assesses how veteran care can be placed at the centre of our understanding of the modern Military Covenant and located as a key issue in contemporary civil–military relations and public policy. Healthcare and welfare provision have become primary manifestations of how the British state fulfils its duty of care towards military personnel. The article aims to present an overview of current provision for veterans of Britain's modern wars and draw conclusions regarding the state's ability to provide short and long‐term healthcare and welfare requirements to veterans as part of the Covenant under the rubric of ‘Big Society’‐inspired policy shifts engendered by the Conservative–Liberal Democrat coalition government.
David Cameron's ‘Problem’ with Women: Representing Women in the Coalition Government
Authors: ANNESLEY CLAIRE , GAINS FRANCESCA
Published: November 2012

Prior to the election in 2010 David Cameron pledged that his first cabinet would comprise one‐third women and would be the most family friendly ever. Since forming the Coalition Government, he appears to have a ‘problem’ with women. We argue that this problem stems from: the weak representation of women in cabinet and across government; the diminishing resources available to government actors to support gender equality policy; and women's exclusion from the key Coalition networks, both formal and informal, that determine government policy.
Feminising British Politics: Six Lessons from Devolution in Scotland and Wales
Authors: MACKAY FIONA , MCALLISTER LAURA
Published: November 2012

Modest levels of female representation at the House of Commons are in sharp contrast to the Nordic‐levels of representation achieved in the Scottish Parliament and the National Assembly for Wales since devolution in 1999. One apparent advantage of devolution is the opportunity that it provides for lesson‐learning across jurisdictions. This article offers six lessons on women's political representation—three positive and three negative—drawn from the experience of devolution in Scotland and Wales. We draw conclusions from these lessons, including the need to keep parties under scrutiny to ensure they deliver on their rhetorical commitments. We also postulate that gender equality might prove too important to be left to political parties and consider whether there is a need to consider stronger measures such as mandatory quotas.
Politics as Theory and Politics as Practice
Authors: BLUNKETT DAVID
Published: November 2012

In 1962, the late Professor Sir Bernard Crick published his seminal work In Defence of Politics. Fifty years on, formal political processes have never been in greater need of defending. In this article, former Home Secretary David Blunkett MP argues that in order to defend politics we need to change the way in which we ‘do’ our politics. In a 21st century response to Professor Crick's challenge to defend the role of politics in providing a counterweight to the financial markets and economic imperialism, Blunkett considers how it is possible to renew political democracy as a force for progressive change. The last five years of political and financial turmoil have seen politics smeared and even, in the case of Greece and Italy, elected governments removed and replaced by technocrats. With the power of government behind the people, it would be possible to foster a whole new spirit of seeing the political process as a way of organising, advising and yes funding a demand for something better from big institutions both public and private.
Introduction: In Defence of Politics
Authors: FLINDERS MATTHEW , GORMLEY‐HEENAN CATHY
Published: November 2012

In a world that is increasingly dominated by literary hyperbole there can be no doubt that Bernard Crick's In Defence of Politics remains a classic text. Classic not just in the sense that it provides a masterly account of the essence, meaning and fragility of democratic politics but classic in the sense that it is written with a style, verve and passion that is rarely found within political science. If the test of pretensions to ‘a classic’ status is that a book defies the passage of time in terms of significance and argument then Crick's Defence would also make the grade for the simple fact that its arguments remain arguably far more important today than they were when they were first published exactly fifty years ago. This article reflects on the contemporary significance of Crick's Defence by defending politics against an updated set of adversaries in the form of: public expectations, marketisation, depoliticisation, the media, and crises before locating the book within the contours of current debates about public disengagement, the rise of ‘disaffected democrats’ and questions concerning the future and relevance of political science.
Freedom, Peace and Politics: Crick and Northern Ireland
Authors: GORMLEY‐HEENAN CATHY , AUGHEY ARTHUR
Published: November 2012

Intimately throughout the 1970s, and in a more detached way for the rest of his life, Bernard Crick thought seriously about the politics of Northern Ireland. Though he produced no systematic study of the Northern Ireland Question, and though at first glance Northern Ireland appeared to be unpropitious territory for the author of In Defence of Politics, his reflections illuminated a deep concern with the relationship between politics, freedom and peace. This article argues that Crick's writing on the subject constitutes a sustained appeal for a ‘realism of pragmatic potential’ in contrast to that despairing ‘realism of impossible certainty’ which, he felt, frustrated hopes for political progress.
Changing the Subject: The Case for ‘Social Politics’
Authors: TAYLOR MATTHEW
Published: November 2012

Running through Bernard Crick's In Defence of Politics is an implicit faith in the ability of liberal democracy to deliver progress. From the perspective of 1962 such optimism seems well founded. After the years of post war austerity there had been more than a decade of steady growth, the middle class was expanding fast providing unprecedented levels of absolute social mobility (more benign and less complicated than the relative social mobility which today's politicians disingenuously claim to pursue). Matthew Taylor explores the case for ‘social politics’.
In Defence of Political Science
Authors: STOKER GERRY
Published: November 2012

The defence of political science rests on a starting proposition that practitioners of political science need to embrace relevance rather than fear. Defending the role of politics in resolving societal dilemmas is in part a responsibility of those who study it and the challenge is significant given evidence of disenchantment with the political process in many established and mew democracies. Political science needs to offer not only an understanding of politics that is theoretical, sophisticated and empirically rigorous but also an approach that is not just problem‐focused but solution‐seeking. Defending political science means defending politics and taking on the challenge of improving its practice.
Competition between meiotic and apomictic pathways during ovule and seed development results in clonality
Authors: Hojsgaard Diego H. , Martínez Eric J. , Quarin Camilo L.
Published: November 2012

Meiotic and apomictic reproductive pathways develop simultaneously in facultative aposporous species, and compete to form a seed as a final goal. This developmental competition was evaluated in tetraploid genotypes of Paspalum malacophyllum in order to understand the low level of sexuality in facultative apomictic populations.

Cyto‐embryology on ovules, flow cytometry on seeds and progeny tests by DNA fingerprinting were used to measure the relative incidence of each meiotic or apomictic pathway along four different stages of the plant's life cycle, namely the beginning and end of gametogenesis, seed formation and adult offspring.

A high variation in the frequencies of sexual and apomictic pathways occurred at the first two stages. A trend of radical decline in realized sexuality was then observed. Sexual and apomictic seeds were produced, but the efficiency of the sexual pathway dropped drastically, and exclusively clonal offspring remained.

Both reproductive pathways are unstable at the beginning of development, and only the apomictic one remains functional. Key factors reducing sexuality are the faster growth and parthenogenetic development in the aposporous pathway, and an (epi)genetically negative background related to the extensive gene de‐regulation pattern responsible for apomixis. The effects of inbreeding depression during post‐fertilization development may further decrease the frequency of effective sexuality.
Nuclear and chloroplast DNA phylogeography of Ficus hirta: obligate pollination mutualism and constraints on range expansion in response to climate change
Authors: Yu Hui , Nason John D.
Published: November 2012

This study uses a phylogeographic approach to investigate how interspecific interactions in an obligate pollination mutualism enhance or constrain dispersal and the range distributions of species through time.

Fifteen populations of Ficus hirta, a bird‐dispersed fig pollinated by a species‐specific fig wasp, were sampled from Thailand to the northern limits of the tropical forest in China. These populations were assayed for six nuclear microsatellite loci and two intergenic chloroplast DNA sequences.

Analyses of range expansion and genetic clustering indicated a relatively slow rate of range expansion from two or more southern glacial refugia. Low nuclear differentiation, combined with high interpopulation differentiation, and phylogeographic structuring of chloroplast variation indicated that seed dispersal has had a greater constraint than obligate interactions with fig wasps on the rate of post‐glacial range expansion.

This study is the first to investigate the phylogeographic history of a widely distributed southeast Asian tropical plant whose distribution extends to the northern limits of tropical forest habitat in China. It is also the first study of Ficus utilizing molecular data to evaluate whether species‐specific pollination is a limitation or an aid to range expansion in response to climate change.
Interrogating food security and infectious animal and plant diseases: a critical introduction
Authors: Ilbery Brian
Published: November 2012

As part of a themed section, this introductory paper provides critical insights into important social science debates associated with food security and animal/plant diseases. Continued volatility in the price of basic foodstuffs on international commodity markets has ensured that food security will be one of the ‘master frames’ of early twentieth century public policy. While increasing food production through ‘sustainable intensification’ characterises the essentially scientific solution to food (in)security issues, other ‘framings’ of food security are also important. These include providing access to affordable and good quality food, reducing food waste and encouraging more urban‐based agriculture. Animal/plant diseases are a considerable threat to food security because of growing trade, travel, transport and tourism. A range of national/international and scientific control measures help to reduce the risk of disease spread, but micro‐scale studies are needed to help understand the practicalities of applying biosecurity controls at local geographical scales.
Intangibles, Can They Explain the Dispersion in Return Rates?
Authors: Görzig Bernd , Gornig Martin
Published: November 2012

It is proven that the observed return rates on capital have an upward bias if firms are producing with unobserved intangible capital. Using a comprehensive firm level database for Germany, this theoretical preposition is supported empirically. Furthermore, by making unobserved intangible capital observable, dispersion in return rates is dramatically reduced. The results support the assumption that a considerable part of the observed dispersion in return rates among firms is attributable to unobserved capital formation in intangible capital.
The loess sequence of Dolní Věstonice, Czech Republic: A new OSL‐based chronology of the Last Climatic Cycle
Authors: Fuchs Markus , Kreutzer Sebastian , Rousseau Denis‐Didier , Antoine Pierre , Hatté Christine , Lagroix France , Moine Olivier , Gauthier Caroline , Svoboda Jiri , Lisá Lenka
Published: November 2012

The Dolní Věstonice loess section in the Czech Republic is well known for its high‐resolution loess–palaeosol sequence of the last interglacial–glacial climatic cycle (Upper Pleistocene). The loess section is situated in a climatic transition zone between oceanic and continental climates and is therefore of great value in reconstructing past regional climate conditions and their interaction with climate systems, in particular that of the North Atlantic. Based on a combination of optically stimulated luminescence (OSL) ages, stratigraphic field observations and magnetic susceptibility measurements, a chrono‐climatic interpretation of the Dolní Věstonice loess section is presented. To establish a reliable Upper Pleistocene chronology, a quartz OSL approach was applied for equivalent dose (De) determination. Monomineralic quartz extracts of three distinct grain sizes, fine (4–11 μm), middle (38–63 μm) and coarse (90–200 μm), were used and compared. Within error limits, the calculated OSL ages are the same for the different grain sizes, and the OSL ages are in stratigraphic order. The established OSL chronology is in agreement with a Weichselian litho‐ and pedostratigraphy. The Dolní Věstonice loess section is characterized by four pedosedimentary subsequences. At the base of the profile, subsequence I is characterized by a distinct Early Glacial soil complex, OSL‐dated to c. 110 to 70 ka, representing one of the most complete records of environmental change in the European loess belt. Subsequence II is allocated to the Lower Pleniglacial and is characterized by laminated sandy loess. Middle Pleniglacial subsequence III is represented by a brown soil complex, and is followed by the uppermost subsequence IV, characterized by a thick body of laminated sandy loess, indicating strong wind activity and a high sedimentation rate of more than ∼1 mm a−1 during the Upper Pleniglacial. According to the OSL chronology, as well as to the sedimentological and palaeopedological investigations, it is likely that the sequence at Dolní Věstonice has recorded most of the climatic events expressed in the NGRIP δ18O reference record between 110 and 70 ka.
A nude mouse model of hypertrophic scar shows morphologic and histologic characteristics of human hypertrophic scar
Authors: Momtazi Moein , Kwan Peter , Ding Jie , Anderson Colin C. , Honardoust Dariush , Goekjian Serge , Tredget Edward E.
Published: November 2012

Hypertrophic scar (HSc) is a fibroproliferative disorder that occurs following deep dermal injury. Lack of a relevant animal model is one barrier toward better understanding its pathophysiology. Our objective is to demonstrate that grafting split‐thickness human skin onto nude mice results in survival of engrafted human skin and murine scars that are morphologically, histologically, and immunohistochemically consistent with human HSc. Twenty nude mice were xenografted with split‐thickness human skin. Animals were euthanized at 30, 60, 120, and 180 days postoperatively. Eighteen controls were autografted with full‐thickness nude mouse skin and euthanized at 30 and 60 days postoperatively. Scar biopsies were harvested at each time point. Blinded scar assessment was performed using a modified Manchester Scar Scale. Histologic analysis included hematoxylin and eosin, Masson's trichrome, toluidine blue, and picrosirius red staining. Immunohistochemistry included anti‐human human leukocyte antigen‐ABC, α‐smooth muscle actin, decorin, and biglycan staining. Xenografted mice developed red, shiny, elevated scars similar to human HSc and supported by blinded scar assessment. Autograft controls appeared morphologically and histologically similar to normal skin. Xenografts survived up to 180 days and showed increased thickness, loss of hair follicles, adnexal structures and rete pegs, hypercellularity, whorled collagen fibers parallel to the surface, myofibroblasts, decreased decorin and increased biglycan expression, and increased mast cell density. Grafting split‐thickness human skin onto nude mice results in persistent scars that show morphologic, histologic, and immunohistochemical consistency with human HSc. Therefore, this model provides a promising technique to study HSc formation and to test novel treatment options.
Topical application of a film‐forming emulgel dressing that controls the release of stratifin and acetylsalicylic acid and improves/prevents hypertrophic scarring
Authors: Rahmani‐Neishaboor Elham , Jallili Reza , Hartwell Ryan , Leung Victor , Carr Nicholas , Ghahary Aziz
Published: November 2012

Here, we evaluate the efficacy of an emulgel dressing to control the release of an antifibrogenic factor, stratifin (SFN), along with an anti‐inflammatory drug, acetylsalicylic acid (ASA), to be used as a wound dressing with hypertrophic scar reducing features. Emulgel dressings were prepared by dispersing positively charged submicron vesicles in carboxymethyl cellulose gel. Release kinetics of SFN/ASA and toxicity for primary skin cells were assessed in vitro. Antifibrogenic efficacy of medicated emulgel dressings was tested on a rabbit ear fibrotic model. Following topical application on the wounds, emulgels formed an occlusive film and controlled the release of SFN and ASA for 7 and 24 hours, respectively. Wounds treated with SFN/ASA‐containing emulgel dressings showed an 80% reduction in scar elevation compared with untreated controls. Topical formulations were nontoxic for cultured human keratinocytes and fibroblasts. Inflammation was significantly controlled in treated wounds, as shown by a reduced number of infiltrated CD3+ T cells (p < 0.001) and macrophages. SFN/ASA‐treated wounds showed a significantly higher (p < 0.001) expression of matrix metalloproteinase‐1, resulting in reduced collagen deposition and less scarring. Film‐forming emulgel dressings that control the release of antifibrogenic and anti‐inflammatory factors provide an excellent treatment option for postburn hypertrophic scar management.
Novel differences in the expression of inflammation‐associated genes between mid‐ and late‐gestational dermal fibroblasts
Authors: Wulff Brian C. , Yu Lianbo , Parent Allison E. , Wilgus Traci A.
Published: November 2012

While cutaneous wounds of late‐gestational fetuses and on through adulthood result in scar formation, wounds incurred early in gestation have been shown to heal scarlessly. Unique properties of fetal fibroblasts are believed to mediate this scarless healing process. In this study, microarray analysis was used to identify differences in the gene expression profiles of cultured fibroblasts from embryonic day 15 (E15; midgestation) and embryonic day 18 (E18; late‐gestation) skin. Sixty‐two genes were differentially expressed and 12 of those genes are associated with inflammation, a process that correlates with scar formation in fetal wounds. One of the differentially expressed inflammatory genes was cyclooxygenase‐1 (COX‐1). COX‐1 was more highly expressed in E18 fibroblasts than in E15 fibroblasts, and these differences were confirmed at the gene and protein level. Differences in COX‐1 protein expression were also observed in fetal skin by immunohistochemical and immunofluorescence staining. The baseline differences in gene expression found in mid‐ and late‐gestational fetal fibroblasts suggest that developmental alterations in fibroblasts could be involved in the transition from scarless to fibrotic fetal wound healing. Furthermore, baseline differences in the expression of inflammatory genes by fibroblasts in E15 and E18 skin may contribute to inflammation and scar formation late in gestation.
Neurocognitive profiles in children with epilepsy
Authors: Kernan Claudia L. , Asarnow Robert , Siddarth Prabha , Gurbani Suresh , Lanphier Erin K. , Sankar Raman , Caplan Rochelle
Published: November 2012

Purpose: The presence of specific neurocognitive deficits may help explain why school achievement and psychosocial functioning are often worse in children with epilepsy than would be predicted by their global intellectual functioning. This study compared children with two forms of epilepsy: localization‐related epilepsy with complex partial seizures (CPS) and childhood absence epilepsy (CAE), to determine whether they display distinct neurocognitive profiles.

Methods: Fifty‐one children with CPS, 31 children with CAE, and 51 controls underwent neuropsychological testing assessing verbal memory, visual memory, and executive functioning. Groups were compared in these cognitive domains. Within‐group analyses were also conducted to examine seizure‐related factors that may be related to neuropsychological test performance.

Key Findings: When compared to controls, children with CPS showed a mild generalized cognitive deficit, whereas children with CAE did not. When we controlled for intelligent quotient (IQ), both epilepsy groups showed poorer performance relative to controls in the domain of verbal memory. When the epilepsy groups were compared to one another, the CPS group performed significantly poorer than the CAE group on a test of generalized cognitive functioning. However, in the specific domains of executive functioning, verbal memory, and visual memory the epilepsy groups did not differ when compared to one another.

Significance: Neurocognitive deficits present in the context of grossly intact global intellectual functioning highlight the importance of neuropsychological screening in both children with CPS and children with CAE.
High Blood Pressure and Resilience to Physical and Cognitive Decline in the Oldest Old: The Leiden 85‐Plus Study
Authors: Sabayan Behnam , Oleksik Anna M. , Maier Andrea B. , van Buchem Mark A. , Poortvliet Rosalinde K. E. , de Ruijter Wouter , Gussekloo Jacobijn , de Craen Anton J. M. , Westendorp Rudi G. J.
Published: November 2012

Objectives

To evaluate the association between various blood pressure (BP) measures at age 85 and future decline in physical and cognitive function the oldest old.

Design

Longitudinal study.

Setting

The population‐based Leiden 85‐plus Study.

Participants

Five hundred seventy‐two 85‐year‐old community‐dwelling individuals.

Measurements

BP was measured at age 85 during home visits. Activities of daily living (ADLs) and Mini‐Mental State Examination (MMSE) were assessed at age 85 and annually thereafter up to age 90. On average, participants were followed for 3.2 years. Cross‐sectional and longitudinal analyses were performed using linear regression models using systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP), and pulse pressure (PP) as the determinants. All analyses were adjusted for sociodemographic and cardiovascular factors.

Results

At age 85, higher SBP and PP were associated with lower ADL disability scores (both P = .01). Similarly, higher SBP, DBP, and MAP were associated with higher MMSE scores (all P < .05). From age 85 onward, higher SBP (P < .001), MAP (P = .01), and PP (P = .003) at age 85 were associated with lower annual increases in ADL disability scores. Likewise, higher SBP (P = .03) and PP (P = .008) at age 85 were associated with lower annual declines in MMSE scores. Additional analyses showed that the association between high BP and lower annual decline in MMSE score was most pronounced in participants with high ADL disability.

Conclusion

In the oldest old, higher SBP and PP are associated with resilience to physical and cognitive decline, especially in individuals with pre‐existing physical disability.
A Quantitative Assessment of the Prion Risk Associated with Wastewater from Carcass‐Handling Facilities
Authors: Adkin Amie , Donaldson Neil , Kelly Louise
Published: November 2012

Wastewater from facilities processing livestock that may harbor transmissible spongiform encephalopathies (TSEs) infectivity is permitted under license for application to land where susceptible livestock may have access. Several previous risk assessments have investigated the risk of bovine spongiform encephalopathy (BSE) associated with wastewater effluents; however, the risk of exposure to classical scrapie and atypical scrapie has not been assessed. With the prevalence of certain TSEs (BSE in cattle and classical scrapie in sheep) steadily in decline, and with considerable changes in the structure of carcass‐processing industries in Great Britain, a reappraisal of the TSE risk posed by wastewater is required. Our results indicate that the predicted number of new TSE infections arising from the spreading of wastewater on pasture over one year would be low, with a mean of one infection every 1,000 years for BSE in cattle (769, 555,556), and one infection every 30 years (16, 2,500), and 33 years (16, 3,333) for classical and atypical scrapie, respectively. It is assumed that the values and assumptions used in this risk assessment remain constant. For BSE in cattle the main contributors are abattoir and rendering effluent, contributing 35% and 22% of the total number of new BSE infections. For TSEs in sheep, effluent from small incinerators and rendering plants are the major contributors (on average 32% and 31% of the total number of new classical scrapie and atypical scrapie infections). This is a reflection of the volume of carcass material and Category 1 material flow through such facilities.
Coercion, Information, and the Success of Sanction Threats
Authors: Whang Taehee , McLean Elena V. , Kuberski Douglas W.
Published: November 2012

This article explores when and why sanction threats succeed in extracting concessions from the targeted country. We focus on two different, albeit not mutually exclusive, mechanisms that can explain the success of sanction threats. The first mechanism relates to incomplete information regarding the sanctioner's determination to impose sanctions and suggests that threats help to extract concessions by revealing the sanctioner's resolve. The second mechanism underscores the direct impact of common interest between the two countries and explains the success of sanction threats by the targeted country's greater dependence on this link between the two countries and the sanctioner's ability to exploit this dependence. We test the hypotheses using a new strategic structural estimator. Our results provide no evidence in favor of the informational hypothesis, while lending robust support for the coercive hypothesis.
Giving new meaning to religious conversion: Churches, redevelopment, and secularization in Toronto
Authors: Hackworth Jason , Gullikson Erin
Published: November 2012

Research on secularization has increased in recent years, particularly amongst urban geographers. Yet the debate is still dominated by competing theories that generally fail to account for the many institutions that impede and facilitate religiosity on the urban landscape. This article is about the role that land use planning regulations have had on changes to the religious landscape in Toronto. The empirical focus is on former churches that have recently been converted to residential uses. The larger conceptual goal is to explore the extent to which these transitions affect the religious landscape in the city and to determine what they can tell us about broader processes of secularization.
The horned Australian burrowing mayfly Jappa (Ephemeroptera: Leptophlebiidae)
Authors: Bae Yeon Jae , Finlay Kyla J. , Campbell Ian C.
Published: November 2012

The horned Australian burrowing mayfly genus Jappa Harker (Leptophlebiidae) is revised based on adult and larval material collected throughout Australia. Five named species [J. campbelli Bae & Finlay, J. edmundsi Skedros & Polhemus, J. furcifera (Eaton), J. serrata Skedros & Polhemus and J. strigata (Eaton 1871) (= J. bicornis Ulmer 1916; = J. kutera Harker 1954, syn. n.)] are recognised, and two new species [J. harkerae n. sp. and J. suteri n. sp.] are described. Descriptions, diagnoses, line‐drawings and images of key characters, distributional information, taxonomic remarks and keys to adults and larvae are provided. The species Jappa tristis Harker 1954 is transferred to the genus Tillyardophlebia Dean.
Dried Tomato‐Flavored Probiotic Cream Cheese with Lactobacillus paracasei
Authors: Santini Marilsa S. S. , Koga Evelyn C. , Aragon Davi C. , Santana Elsa H. W. , Costa Marcela R. , Costa Giselle N. , Aragon‐Alegro Lina C.
Published: November 2012

Abstract:  A dried tomato‐flavored probiotic cream cheese (P) containing Lactobacillus paracasei Lpc‐37 was developed for the purpose of this study. The same product, but without probiotic addition (C) was used as control. Lactococcus lactis subsp. lactis and Lactococcus lactis subsp. cremoris were used as lactic starter cultures. Chemical composition analyses and sensory tests were performed on days 1 and 7, respectively. Titratable acidity, pH value and L. paracasei population were determined every 7 d during the refrigerated storage (21 d) of the cream cheeses. The experiment and analyses were performed in triplicate, using standard methods. Probiotic population remained greater than 107 CFU/g throughout the storage period, thereby characterizing the product as potentially probiotic. Cream cheeses C and P did not differ on the sensory tests, both obtaining good overall acceptance by the consumers, of which 82.6% stated that they certainly or probably would buy the product.

Practical Application:  Lactobacillus paracasei Lpc‐37 is a probiotic bacterium and clinical studies have shown that this microorganism beneficially affects its host. In general, dried tomato‐flavored products and cream cheese are products with good acceptance by the consumers. Thus, regular consumption of the probiotic cream cheese developed in this study may have positive effects on health and well being of people if incorporated into their diet.
Detection of Enterotoxigenic Staphylococcus aureus in Raw Milk and Dairy Products by Multiplex PCR
Authors: Gücükoğlu Ali , Onur Kevenk T. , Uyanik Tolga , Çadirci Özgür , Terzi Göknur , Alişarli Mustafa
Published: November 2012

Abstract:  The aim of this study was to investigate the prevalence of enterotoxigenic Staphylococcus aureus in 122 samples, including 60 raw milk, 32 white cheese, 10 kashar cheese, 10 butter, and 10 ice cream samples obtained from Samsun province, Turkey. In this study, S. aureus was detected in 64 samples, including raw milk (45/60; 75%), white cheese (12/32; 37.5%), kashar cheese (3/10; 30%), butter (3/10; 30%), and ice cream (1/10; 10%) samples. A total of 81 isolates were identified as S. aureus by PCR with the presence of 16S rRNA and nuc genes. The presence of genes encoding the staphylococcal enterotoxins (SEs) SEA, SEB, SEC, and SED was detected by multiplex PCR. According to the analysis, seven isolates from the raw milk samples (7/51; 13.7%) were enterotoxigenic; five of them produced SEA (5/7; 71.4%), one produced SEB (1/7; 14.2%), and one produced SEA+SEB (1/7; 14.2%). Four isolates from the white cheese samples (4/21; 19%) produced the SEA (1/4; 25%), SEC (1/4; 25%), SED (1/4; 25%), and SEA+SED (1/4; 25%) toxins. Two isolates from the kashar cheese samples (2/4; 50%) were found to be enterotoxigenic; one produced SEA (1/2; 50%) and the other produced SED (1/2; 50%). One isolate from the butter samples (1/4; 25%) showed enterotoxigenic character (SEB, 1/1; 100%). The products were found to be potentially hazardous to public health because of the fact that levels of contamination were higher than 105–106 cfu/g ml in 39% (25/64, 17 raw milk, 7 white cheese, and 1 butter) of the analyzed samples.
The Conversion of Perhydropolysilazane into SiON Films Characterized by X‐Ray Photoelectron Spectroscopy
Authors: Wang Kaishi , Zheng Xiaohao , Ohuchi Fumio S. , Bordia Rajendra K.
Published: November 2012

Silicon oxynitride (SiON) films of ~1 μm thickness were made by dip coating and subsequent thermal treatment of a preceramic polymer: perhydropolysilazane (PHPS). X‐ray photoelectron spectroscopy was used to analyze the surface of a series of SiON films annealed in air between room temperature and 800°C. Results reveal that the progressive changes in the bonding states of silicon, oxygen, and nitrogen due to different degrees of annealing lead to a systematic evolution of atomic ratios of the films. It is shown that PHPS forms a unique amorphous SiOxNy material upon annealing in air up to 800°C with evolving compositions, instead of a mixture of Si3N4 and SiO2.
Modeling of Pore Structure Evolution Between Bundles of Plain Woven Fabrics During Chemical Vapor Infiltration Process: The Influence of Preform Geometry
Authors: Guan Kang , Cheng Laifei , Zeng Qingfeng , Zhang Litong , Deng Juanli , Li Kaiyuan , Li Hui
Published: November 2012

A three‐dimensional model combining the nonconservative level set method and the steady‐state diffusion equation is presented for studying evolving pore structure between bundles of plain woven fabrics during chemical vapor infiltration process. Parametric studies have been conducted to determine the sensitivity of the evolution of structural properties and effective gas diffusion coefficients to the geometric parameters of the preform. Based on our results, some analytical expressions are proposed to estimate the evolution of structural properties and the tortuosity. The prediction of the presented models is well consistent with the existing data of experiments.
Luminal uptake of Vibrio (Listonella) anguillarum by shed enterocytes – a novel early defence strategy in larval fish
Authors: Rekecki A , Ringø E , Olsen R , Myklebust R , Dierckens K , Bergh Ø , Laureau S , Cornelissen M , Ducatelle R , Decostere A , Bossier P , Van den Broeck W
Published: November 2012

As adhesion and translocation through fish gut enterocytes of the pathogen Vibrio (Listonella) anguillarum are not well investigated, the effective cause of disease and mortality outbreaks in larval sea bass, Dicentrarchus labrax, suffering from vibriosis is unknown. We detected V. anguillarum within the gut of experimentally infected gnotobiotic sea bass larvae using transmission electron microscopy and immunogold labelling. Intact bacteria were observed in close contact with the apical brush border in the gut lumen. Enterocytes contained lysosomes positive for protein A‐gold particles suggesting intracellular elimination of bacterial fragments. Shed intestinal cells were regularly visualized in the gut lumen in late stages of exposure. Some of the luminal cells showed invagination and putative engulfment of bacterial structures by pseudopod‐like formations. The engulfed structures were positive for protein A‐colloidal gold indicating that these structures were V. anguillarum. Immunogold positive thread‐like structures secreted by V. anguillarum suggested the presence of outer membrane vesicles (MVs) hypothesizing that MVs are potent transporters of active virulence factors to sea bass gut cells suggestive for a substantial role in biofilm formation and pathogenesis. We put forward the hypothesis that MVs are important in the pathogenesis of V. anguillarum in sea bass larvae.
Intramuscular architecture of the autochthonous back muscles in humans
Authors: Stark Heiko , Fröber Rosemarie , Schilling Nadja
Published: November 2012

Many training concepts take muscle properties such as contraction speed or muscle topography into account to achieve an optimal training outcome. Thus far, the internal architecture of muscles has largely been neglected, although it is well known that parameters such as pennation angles or the lengths of fascicles but also the proportions of fleshy and tendinous fascicle parts have a major impact on the contraction behaviour of a muscle. Here, we present the most detailed description of the intramuscular fascicle architecture of the human perivertebral muscles available so far. For this, one adult male cadaver was studied. Our general approach was to digitize the geometry of each fascicle of the muscles of back proper (Erector spinae) – the Spinalis thoracis, Iliocostalis lumborum, Longissimus thoracis and the Multifidus thoracis et lumborum – and of the deep muscles of the abdomen – Psoas minor, Psoas major and Quadratus lumborum – during a layerwise dissection. Architectural parameters such as fascicle angles to the sagittal and the frontal planes as well as fascicle lengths were determined for each fascicle, and are discussed regarding their consequences for the function of the muscle. For example, compared with the other dorsovertebral muscles, the Longissimus thoracis can produce greater shortening distances because of its relatively long fleshy portions, and it can store more elastic energy due to both its relatively long fleshy and tendinous fascicle portions. The Quadratus lumborum was outstanding because of its many architectural subunits defined by distinct attachment sites and fascicle lengths. The presented database will improve biomechanical models of the human trunk by allowing the incorporation of anisotropic muscle properties such as the fascicle direction into finite element models. This information will help to increase our understanding of the functionality of the human back musculature, and may thereby improve future training concepts.