bluuebunny/crossref_metadata_2025 huggingface dataset:
In silico studies on quercetin, myricetin, and kaempferol in inhibiting TGF-β1 and galectin-3 for cardiac fibrosis management
Authors: Suryono Suryono , Amien Muhammad I. , Tohari Achmad I. , Saputra Antonius D. , Hidayat Muhammad RF. , Ramadhan Hazbina F.
Published: January 2025

Cardiac fibrosis remains as the leading cause of death worldwide and is often associated with elevated levels of transforming growth factor-β 1 (TGF-β1) and galectin-3, making them potential therapeutic targets. Recent studies revealed that quercetin, myricetin, and kaempferol have the biological effect for several cardiovascular diseases. However, the investigation into this topic through molecular models and analysis remain unexplored. The aim of this study was to evaluate the potential effect of quercetin, myricetin, and kaempferol which targeted TGF-β1 and galectin-3. In this study, quercetin, myricetin, and kaempferol roled as the tested ligands. Subsequently, colchicine and native ligand acted as control ligands that were screened through molecular docking against TGF-β1 and galectin-3 using AutoDock tools to identify the potential inhibitor. The stability of ligand-receptor complexes was assessed through molecular dynamic (MD) simulations using NMAD. Absorption, Distribution, Metabolism, Excretion and toxicity (ADMET) prediction were also performed using ADMETlab 2.0. Molecular docking analysis revealed that quercetin, myricetin, and kaempferol exhibited strong binding affinity which are -8.9 kcal/mol, -8.5 kcal/mol, -7.6 kcal/mol respectively with TGF-β1, and -7.5 kcal/mol, -7.0 kcal/mol, -5.7 kcal/mol respectively with galetcin-3; low inhibition constant (Ki); and stable interaction with the active sites of TGF-β1 and galectin-3. MD simulations confirmed the stability and compactness of the ligand-receptor complexes. ADMET analysis also showed high Plasma Protein Binding (PPB) values (quercetin: 95%, myricetin: 92%, and kaempferol: 97%) and moderate clearance values (quercetin: 8.284%, myricetin, and 7.716%, kaempferol: 6.868%) for the tested compounds. In conclusion, the in silico analyses suggested that quercetin, myricetin, and kaempferol are promising for cardiac fibrosis therapies by inhibiting TGF-β1 and galectin-3.
Upaya Meningkatkan Kesadaran dan Partisipasi Masyarakat Melalui Kegiatan Donor Darah Di Lingkungan Masjid Imanuddin Graha Raya Bintaro
Authors: Hartati Leni , Sutomo Sutomo , Reza Bobby
Published: January 2025

This Blood Donation Activity aims to increase public awareness and participation in blood donation in the Imanuddin Mosque environment, Graha Raya Bintaro. Blood donation is a form of humanitarian action that can help save lives and support blood needs in health facilities. The implementation of this activity involves various parties, including mosque administrators, community organizations, and health agencies, with a collaborative approach to ensure the sustainability and effectiveness of the program. This activity was carried out on August 31, 2024, involving more than 98 participants who participated as donors. The results of this activity showed the high enthusiasm of the community in supporting the blood donation program, which can be seen from the increase in the number of donors compared to previous activities. In addition, this activity also provides education about the importance of regular blood donation, so that it is expected to become a sustainable program in the mosque environment. The conclusion of this PKM is the importance of the active role of the community in blood donation activities, as well as the need for collaboration between various parties to achieve the success of the activity.
Pelatihan Smart PLS Bagi Para Peneliti Akuntansi dan Bisnis di Universitas Binaniaga Indonesia
Authors: Sitorus Riris Rotua
Published: January 2025

The purpose of this training is to educate accounting and business researchers at Binaniaga Indonesia University, on how to process research data in accounting and business using Smart PLS software. Primarily how to run data based on structural equation modeling, which consists of intervening models and moderating models. There are two methods used, the first is the lecture method for explaining concepts and theories. Second, the method of practical data processing. The number of participants who filled out the evaluation form was 20 participants. The evaluation instrument used was questions on the Google form related to understanding the training material. The evaluation results showed an increase in the participants' abilities. First, an increase in the ability to prepare excel csv data and data input skills, as well as the ability to draw research models. Second, an increase in the ability to conduct validity and reliability tests, as well as the reduction process for invalid questions. Third, an increase in the ability to evaluate r square and goodness of fit, as well as compiling structural equations. Fourth, the ability to test the intervening SEM model, as well as the interpretation of direct and indirect effects. Fifth, the ability to test the moderating SEM model, as well as the interpretation of the moderating effect.
NEW BIOMARKERS FOR EARLY DETECTION AND PROGNOSIS OF THERAPEUTIC
APPROACHES TO GASTRIC CANCER:
A LITERATURE REVIEW
Authors: Aitmagambetova M. , Tuleayeva A. , Kereeva N. , Akhmetova S. , Koishybaev A. , Essultanova G.
Published: January 2025

Relevance: Gastric cancer is a heterogeneous disease whose development is associated with both genetic and acquired somatic mutations. Identifying optimal diagnostic markers for gastric cancer with high sensitivity and specificity will improve patient survival rates and contribute to the advancement of personalized medicine. Identifying biomarkers by integrating clinical data and comprehensive genomic analysis can significantly enhance the accuracy of diagnosis, disease progression prediction, recurrence risk assessment, and treatment response. This work discusses promising biological markers that may be used for early diagnosis of gastric cancer and predicting the effectiveness of various treatment methods.The purpose was to analyze current scientific literature to identify new and recently developed biomarkers for diagnostic and prognostic value concerning malignant stomach tumors.Methods: In this review, we searched electronic medical literature in the PubMed and Google Scholar databases. The search utilized keywords: “biomarker,” “gastric cancer,” “early detection,” “diagnosis,” and “prognosis.” Full-text publications in English and Russian, available in open access and focused on the role of biomarkers in early diagnosis and prognosis of gastric cancer, published in the last ten years, were included. Case reports, correspondence, letters, and studies not conducted on humans were excluded from the review. The analysis revealed an insufficient accuracy of existing biomarkers for gastric cancer diagnosis and prognosis. Within the modern approach to disease classification framework, a new molecular type was proposed: tumors infected with the Epstein-Barr virus, tumors with microsatellite instability, genomically stable tumors, and chromosomally unstable tumors.Conclusion: Current research on gastric cancer focuses on identifying and validating new non-invasive biomarkers. Further studies are necessary to enhance sensitivity and broaden the application of these biomarkers for early diagnosis and predicting treatment efficacy
ANALYSIS OF THE INCIDENCE OF MALIGNANT NEOPLASMS OF THE ORAL CAVITY
IN THE CITY OF SHYMKENT
Authors: Kaldygozova G. , Rysbanbetova Zh. , Turgunbaeva S. , Sarkulova I. , Taukebay T.
Published: January 2025

Relevance: In Kazakhstan, an exponentially growing number of people live with bad habits (smoking, drinking alcohol, drug abuse,
etc.), which are the main cause of oral cancer. It is necessary to inform the population about preventive measures and periodically conduct screening examinations.
The study aimed to analyze the incidence and mortality rates of the population from oral cancer for 2019-2022 in the city of Shymkent.
Methods: A retrospective study of patients with oral cancer in the oncology dispensary of Shymkent from 2019 to 2022 was conducted.
Results: The low percentage of early detection of this pathology in the city of Shymkent creates the need to intensify the work of the
Shymkent city clinic on the early detection of oral cancer.
Conclusion: Within the guaranteed volume of medical care, we recommend that men aged 40 to 70 with bad habits not only in rural
areas but also in cities undergo examination once a year for early detection of oral cancer.
Kronik ruhsal bozukluk tanısı alan hastalarının toplum ruh sağlığı merkezine devam durumuna göre sosyal işlevsellik, iç görü ve ilaç uyumlarının karşılaştırılması
Authors: Şener Beyza , Karaca Aysel
Published: January 2025

Amaç: Bu çalışmanın amacı, Toplum Ruh Sağlığı Merkezi’ne (TRSM) kayıtlı hastaların TRSM programına devam durumuna göre hastaların sosyal işlevsellik, içgörü ve ilaç uyumlarının karşılaştırılmasıdır.
Gereç ve Yöntem: Araştırmanın örneklemini İzmit ili Halıdere Toplum Ruh Sağlığı Merkezi’ne Eylül 2019 itibariyle en az bir yıldır kayıtlı olan şizofreni, bipolar bozukluk, şizoaffektif bozukluk ve belirlenmemiş organik olmayan psikoz tanısı alan yetişkin 130 hasta oluşturmuştur. Bu hastalar Toplum Ruh Sağlığı Merkezine devam eden (n:65) ve etmeyen (n:65) olmak üzere iki gruba ayrılmıştır. Veri toplama araçları olarak; Sosyo-demografik Bilgi Formu, Morisky Uyum Ölçeği, İçgörünün Üç Bileşenini Değerlendirme Ölçeği ve Sosyal İşlevsellik Ölçeği kullanılmıştır. Verilerin analizinde; kategorik değişkenler için sıklıklar (sayı, yüzde), sayısal değişkenler için ise tanımlayıcı istatistikler (ortalama, standart sapma) kullanılmıştır. Bağımsız iki grup arasındaki farklılıklara Bağımsız Örneklem T Testi ve iki bağımsız sayısal değişken arasındaki ilişkiler ise Pearson Korelasyon katsayısı ile incelenmiştir.
Bulgular: Toplum Ruh Sağlığı Merkezine devam eden hastaların Sosyal İşlevsellik Ölçeği toplam, İç Görünün Üç Bileşenini Değerlendirme Ölçeği toplam ve Morisky Uyum Ölçeği toplam puanları devam etmeyen hastalara göre anlamlı düzeyde yüksek bulunmuştur (p
Measuring the impact of economic reform policies in the financial sector on inflation rates in Sudan using the ARDL model,
Authors: Mohamed Elrasheid Tarig , Mirghani Fatima
Published: January 2025

The study aimed to measure the impact of economic reform policies that were applied in the financial sector on inflation rates in Sudan during the period (1990-2020) using the autoregressive Distributed lags Model (ARDL), and it concluded that there is a positive, statistically significant relationship between economic reform policies. The financial sector, which included banks' assets, capital and reserves, Khartoum Stock Exchange Index, and market capitalization was applied to inflation rates.
قياس أثر سياسات الاصلاح الاقتصادي في القطاع المالي على معدلات التضخم في السودان باستخدام نموذج ARDL
الملخص: هدفت الدراسة إلى قياس أثر سياسات الإصلاح الاقتصادي التي تم تطبيقها في القطاع المالي على معدلات التضخم في السودان خلال الفترة  (2020-1990)  باستخدام نموذج الانحدار الذاتي ذى الفجوات الزمنية الموزعة  ARDL، وتوصلت الى وجود علاقة ايجابية ذات دلالة إحصائية بين سياسات الاصلاح الاقتصادي الخاصة بالقطاع المالي والتي شملت كلاً من أصول البنوك، رأس المال والاحتياطيات، مؤشر سوق الخرطوم للأوا رق المالية، رأس المال السوقي التي تم تطبيقها على معدلات التضخم.
The scarcity of natural resources and the unlimited waste characteristics: The necessity of conciliation, what are the possibilities of application in Algeria?
Authors: Hachemi-Douici Naima , Dorbane-Nasri Nadia
Published: January 2025

From now on, the waste issue belongs to the problem of environmental degradation and that of the scarcity of natural resources. In this context, it’s unavoidable to move from the concept of draining waste to the one of rating them. Therefore, the waste becomes a resource.In order to take part in this new trend, since the 2000s, Algeria has engaged in a public waste management policy with different ambitious action programs. Moreover, the government has devoted institutional, financial and human means, but despite of that, the set aims are far from being achieved.This article shows us that, waste management remains an issue in Algeria. However, this situation is explained among other things by the priority given by the public authorities to the trash disposal, the low recovery rate, and the unfavorable socio-economic background.
La rareté des ressources naturelles et le caractère illimite des déchets : La nécessité de conciliation, quelles possibilités d’application en Algérie ?
RESUME: La problématique des déchets s'inscrit, désormais, dans celle de la dégradation de l'environnement et de la rareté des ressources naturelles. Dans cette optique, il est inéluctable de passer d'une logique d'élimination des déchets à celle de la valorisation. Le déchet devient ainsi, une ressource. Pour se greffer dans cette nouvelle tendance, l’Algérie a engagé, depuis les années 2000, une politique publique de gestion des déchets, des programmes d'actions ambitieux et elle a mobilisé des moyens institutionnels, financiers, humains et autres, mais les objectifs fixés sont loin d’être atteint.Cet article nous montre que la gestion des déchets en Algérie demeure problématique. Cette situation s'explique, entre autres, par la priorité accordée par les pouvoirs publics à l'élimination des déchets, faible taux de valorisation et le contexte socioéconomique défavorable.
The impact of fiscal policy components on foreign direct investment in Algeria during the period (2000-2020)
Authors: SAHEL Mohamed , BENTAFAT Abdelhak
Published: January 2025

The main objective of this study was to determine the degree of impact of the components of the fiscal policy on foreign direct investment flows in Algeria during the period (2000-2020), using a multiple linear regression model.The study concluded that there is a negative and significant effect of the external public debt on foreign direct investment in Algeria, as an increase in the external public debt by 1 unit leads to a subsequent decrease in foreign direct investment by -1.119 units, while there was no effect between each of the variable Ordinary collection, public spending variable, and foreign direct investment.
أثر مكونات السياسة المالية على الاستثمار الأجنبي المباشر في الجزائر خلال الفترة  2000-2020
الملخص: كان الهدف الرئيسي من هذه الدراسة هو تحديد درجة تأثير مكونات السياسة المالية على تدفقات الاستثمار الأجنبي المباشر في الجزائر خلال الفترة (2000-2020)، وذلك باستخدام نموذج الانحدار الخطي المتعدد . خلصت الدراسة إلى وجود أثر سلبي ومعنوي للدين العام الخارجي على الاستثمار الأجنبي المباشر في الجزائر، حيث أن زيادة الدين العام الخارجي بمقدار 1 وحدة يؤدي إلى انخفاض لاحق في الاستثمار الأجنبي المباشر بمقدار 1.119وحدة، في حين لم يكن هناك أثر بين كل من "متغير الجباية العادية، متغير الانفاق العام" والاستثمار الأجنبي المباشر .
The rejuvenation of the brand through Social Media
Authors: BENDERDOUCHE Narimane
Published: January 2025

The rejuvenation of the brand through social media has become a key issue for traditional brands that want to target millennials. Indeed, in the digital age, researchers are on the lookout for new technologies in order to develop the best possible strategies and to be more efficient in a market where competition is becoming harder. Thus, the recent study aims to highlight strategies capable of rejuvenating a brand through socialmedia.
LE RAJEUNISSEMENT DE LA MARQUE PAR LES MÉDIAS SOCIAUX
Résumé:
Le rajeunissement de la marque par les médias sociaux est devenu un enjeu majeur pour les marques traditionnelles qui souhaitent cibler la génération Y. En effet, à l’ère du numérique, les chercheurs sont à l’affût de nouvelles technologies afin de développer les meilleures stratégies possible, et cela dans le but d’être plus performants dans un marché où la concurrence est dure et ardue. La récente étude vise à mettre en lumière les éventuelles stratégies possibles pour rajeunir une marque à travers les médias sociaux.
Effect of Monetary policy on food inflation in Nigeria: Evidence from Quantile Regression Model
Authors: Abdulrahman Abdullahi Nadani , Mohammed Dansabo Usman , Yaro Yaro , Asooso Aondoawase
Published: January 2025

This study examines the effect of monetary policy on food inflation in Nigeria using a quantile regression model and monthly data from January 2004 to October 2021. The results of the study reveal that food inflation falls by 0.41 and 0.69 percent at the 25th and 50th quantiles, respectively, following a restrictive monetary policy by the apex bank in Nigeria. As the exchange rate depreciates, food inflation rises by 8.92 percent at the 25th quantile, 12.6 percent at the median, and later falls to 16 percent at the 90th quantile. The real GDP is significant across all quantiles. Lastly, the oil price is positive and significant at the OLS estimate and the 90th quantile. The study recommends unconventional monetary policies for improving supply chain of agricultural products.
Dattatreya’s Philosophical Teachings: An Ecocritical Perspective
Authors: Dr. Damaru Chandra Bhatta
Published: January 2025

This article explores Dattatreya’s philosophical teachings from an ecocritical perspective. Also, it reviews the perspective of ecocriticism and shows how that ecocritical perspective is useful to analyze the philosophical teachings of Dattatreya, which he learned from his 24 gurus of the natural and human world. To explain Dattatreya’s teachings from the perspective of ecocriticism, we look at how they show and affect the connection between people, nature, and culture. Ecocriticism studies how literature and culture relate to the environment, highlighting how important nature is to human life. Ecocriticism was a term coined in the late 1970s by combining “criticism” with a shortened form of “ecology”—the science that investigates the interrelations of all forms of plant and animal life with each other and with their physical habitats. Ecocriticism, also known as environmental criticism or green studies, refers to writings that examine the relationship between literature and the environment, with a strong focus on the harm humans are causing to nature. Dattatreya, a respected sage and God in Hindu tradition, is famous for his special way of achieving enlightenment. He learned from 24 different gurus (“teachers”) each representing various aspects of nature and life: earth, wind, sky, water, fire, moon, sun, pigeon, python, ocean, moth, bumblebee, elephant, honey collector, deer, fish, prostitute Pingala, osprey, baby, maiden, arrow-maker, snake, spider, and wasp.  Dattatreya’s philosophy combines Vedantic and Yogic teachings, focusing on achieving self-realization and spiritual enlightenment. The story of Dattatreya, honored as an incarnation of the Divine Trinity of Brahma, Vishnu, and Shiva, appears in some Puranas and minor Upanishads. The 24 teachings learned by Dattatreya are worth discussing from an ecocritical perspective. These teachings, if followed, can save us from deteriorating ecological crises and degrading human values.
Breaking the Silence of Patriarchal Apathy: The Graphic Reinscription of Women’s Reproductive Health in Lucy Knisley’s Kid Gloves
Authors: Dr. Kusumika Sarkar
Published: January 2025

In the field of women’s reproductive health, the narratives of the ‘Wandering womb’, the non-fulfilment of sexual desires, or failure towards the duty of childbearing as reasons for women’s health issues, both physiological as well as psychological have been rife since ancient times. Even now, after the rejection of many of these theories, making way for new scientific explanations and understandings, there remain many differences in the manner in which health facilities are handed out to women when compared to men. Especially when it comes to reproductive health, depictions in literature, as well as other cultural productions, have often either glossed over these matters or have presented them in an intentionally euphemistic manner, albeit in the guise of decency. The reality of the difficulties of women’s reproductive illnesses (self-perception) complicated both by birth control fertility treatments as well as the pregnancy in itself that often bring several complications in a woman’s body are usually never considered sickness (societal recognition) or disease (recognition by medical practitioners). In using the terms illness, sickness and disease, the paper is carrying forward the accepted critical difference between the three first articulated by A. Twaddle (1964) Through the study of Lucy Knisley’s refreshingly frank graphic memoir Kid Gloves: Nine Months of Careful Chaos, this paper aims to question the process of normalisation that turns many of women’s illnesses suffered during pregnancy or in the process of birth control as ‘side-effects’ and unrecognised, how they become impossible to cure, in the first place. The paper will show how the text not only uncovers the mystification surrounding women’s health in general, revealing the patriarchal attitudes that inform such notions, but does so in a simple manner that is also fun to read- making it a compelling feminist text.
From Bench to Brain: A Metadata-driven Approach to Research Data Management in a Collaborative Neuroscientific Research Center
Authors: Pacharra Marlene , Otto Tobias , Winter Nina Olivia Caroline
Published: January 2025

Research data management (RDM) is key to fast and effective cooperation in collaborative research projects, especially when several scientific disciplines are involved. Critical steps in RDM are the agreement and implementation of common standards for metadata and data storage. The practice paper outlines the approach of the interdisciplinary Collaborative Research Center (CRC) 1280 ‘Extinction Learning’ with 81 researchers from biology, psychology, medicine, and computational neuroscience across four different institutions. This framework can serve as a transferable model for other collaborative research initiatives lacking predefined metadata schemas or repositories.
Specifically, the iterative process of agreeing on 16 metadata fields that correspond most highly with the involved research disciplines for collaboration is discussed. To increase reusability, mappings to the Dublin Core and DataCite bibliometric standards were established for descriptive metadata fields. Moreover, we deploy controlled vocabularies and terminology tailored to the respective disciplines and to the organizational structure of the CRC. Using this metadata schema, neuroscientific data from more than 3,200 human subjects and lab animals are currently shared within the CRC. To enable implementation of this schema in active research, open-source applications have been developed that store metadata as local JSON files along with research data and make metadata searchable. The development of the metadata schema and its subsequent use are illustrated with particular emphasis on design principles that allow for reuse in other RDM domains and the lessons learned.
Characteristics of Directors, Composition of Board Committees, and Firm Performance: The Case of U.S. Equity REITs
Authors: Noguera Magdy C.
Published: January 2025

This paper investigates the composition of REIT board committees in terms of the real estate expertise of the directors, type of director, gender, and tenure and the impact of these characteristics on REIT performance. The sample comprises data at the director level for 65 U.S. equity REITs during the period of 2010-2019. Using chi-square tests and logistic panel regressions, I provide evidence that the profile of REIT board members varies depending on their assignment to different committees and that, overall, the average REIT director does not match the expected director profile of having significant real estate expertise or long board tenure. I also find that finance and investment committee members are directors with very different characteristics despite tat these committees are function-related advisory committees and real estate expertise is associated with investment committee membership only. Furthermore, using panel fixed effects regressions, I find that the composition of REIT committees matters for REIT performance, especially in the case of investment committees for which the presence of outside and inside directors with real estate expertise and long tenure is associated with higher REIT performance. To the best of my knowledge, this is the first study that investigates the composition of REIT board committees and its impact on REIT performance. The findings are of interest to researchers and practitioners as they show the key characteristics of directors for REIT monitoring and advisory committees and their effect on REIT performance, and this information can assist in the understanding of REIT board functioning and the designing of the optimal REIT board.
Resilience Tested: Interplay between Mortgage Channels and Natural Disasters on Housing Price
Authors: Nugroho Ariyanto Adhi , Purwaningsih Yunastiti , Hakim Lukman , Suryanto Suryanto
Published: January 2025

The existing body of literature on the interaction between mortgage channels and natural disasters on housing prices is limited. As a vast archipelagic nation, Indonesia is highly susceptible to natural disasters. Our research utilizes quarterly data from Indonesian provinces between 2012 and 2019, and employs panel regression to evaluate the influence of mortgage channels and natural disasters on housing prices. The results indicate varying impacts on housing prices based on the type and intensity of natural disasters, alongside regional development, which remain robust under various tests. Despite potential disruptions, the overall availability and effects of housing loans on housing prices remain relatively stable, thus highlighting the significant role of mortgage channels in shaping housing prices under different circumstances. This understanding has the potential to guide stakeholders in enhancing disaster management strategies and overseeing housing prices, and takes into consideration the distinct vulnerabilities found in each region. Due to the unpredictable nature of natural calamities, it is crucial to establish plans for pre-disaster strategies. Using risk-disaster clusters allows the government to customize housing policies based on particular vulnerability categorizations instead of utilizing a standardized approach nationwide. Additionally, the financial sector has the opportunity to integrate regional risk assessments in the decision-making process for the distribution of housing loans.
Neurological immune-related toxicity to ipilimumab/nivolumab therapy in malignant melanoma: A challenging case report
Authors: da Mata Diana Baptista , Rafaela Rodrigues Patrícia , Oliveira Vanessa , Ferreira Fábio , Ferreira Paula
Published: January 2025

Introduction: Malignant melanoma poses a significant threat due to its aggressiveness and high fatality rates. Recent advances in immunotherapy and targeted molecular therapies have transformed the treatment landscape for advanced melanoma, improving overall survival. However, the rising use of immune checkpoint inhibitors (ICIs) introduces complexities, particularly in neurological immune-related adverse events (irAEs), necessitating careful consideration and multidisciplinary management.

Case Report: We report the case of a 77-year-old woman with stage IV cutaneous melanoma, which was hospitalized with polyneuropathy following immunotherapy treatment with ipilimumab and nivolumab combination. The complex presentation involved considerations of COVID-19 vaccination, detection of Epstein–Barr virus (EBV) in cerebrospinal fluid, and the challenge of distinguishing infectious from immune-related causes. The multidisciplinary team navigated multiple diagnostic uncertainties. The patient’s clinical evolution, including complications and treatment responses, provided insights into managing severe neurological irAEs associated with immunotherapy.

Conclusion: Neurologic immune-related (IR) toxicity is well established, and it may led to severe adverse events, which are complex to diagnose and manage. This case report highlights the challenges and difficulties found, with relevant confounding factors, which arise the relevance of the need of a multidisciplinary team to deal with neurologic immune-related toxicities.
Violencia de Género, debates y tensiones del Movimiento Feminista (1973-2020)
Authors: Cirano Herrera Karina
Published: January 2025

La violencia de género en Chile es un problema estructural que el Movimiento Feminista y de Mujeres viene discutiendo de manera activa hace décadas y que se perfila en contexto de Dictadura. Luego, al retorno de la democracia neoliberal, los debates en torno a la participación se hicieron parte de la agenda del Movimiento Feminista, dada la creación de organismos estatales especializados de género. Por ello, el siguiente ensayo busca revisar las teorizaciones y tensiones del movimiento feminista amplio desde una perspectiva histórica con relación a la institucionalización, academización, desmovilización y el surgimiento de políticas públicas contra la Violencia de Género, dando cuenta de tres conclusiones: i) el rol de los movimientos sociales y las oportunidades de acción colectiva en tensión al Estado, ii)la institucionalización del problema como oportunidad para dar respuestas a violencias estructurales y iii)la discusión en torno a la participación efectiva del movimiento feminista y las políticas internacionales.
La Dimensión de Género en las Políticas Públicas para la Pequeña Agricultura: Un Estudio con las Agricultoras de Yumbel, Chile
Authors: González Amparo
Published: January 2025

Este artículo analiza la dimensión de género en las políticas públicas para la pequeña agricultura en Chile, enfatizando la interacción entre género, políticas públicas y desarrollo rural. Debido al uso de una metodología participativa el conocimiento adquirido durante este estudio fue co-construido a través de entrevistas semi-estructuradas con mujeres pequeñas agricultoras de Yumbel, Región del Bio-Bío, Chile, donde se develaron los principales desafíos que dificultan su desarrollo y participación en los espacios públicos. Los resultados indican que, aunque estas mujeres ocupan una posición crucial en la agricultura a pequeña escala, se enfrentan a obstáculos estructurales debido a políticas que no integran adecuadamente la perspectiva de género. Se presentan dos desafíos claves: La migración y la transformación demográfica y la ausencia de perspectiva de género en las politicas del sector. A partir de estos desafíos, se sugieren recomendaciones para políticas agrícolas inclusivas, que reconozcan y apoyen el papel de las mujeres en la pequeña agricultura como vía para un desarrollo agrícola sostenible en Chile. Nunca se insistirá lo suficiente en la importancia de este reconocimiento y apoyo, empoderar a las mujeres pequeñas agricultoras contribuye al crecimiento general y a la sostenibilidad del sector agrícola.
Nuevas agencias sociales y políticas: Un análisis de los Algoritmos y las Plataformas Digitales en el proceso constituyente chileno del año 2022
Authors: Castillo Pablo , Briones Jorge
Published: January 2025

El presente artículo estudia la emergencia de las plataformas digitales como nueva agencia social digital que conforma el proceso constituyente chileno del año 2022, para ello se recurrió a una diseminación del objeto digital plataforma desde dos ejes; Por un lado, su manifestación puramente formal y tecnológica acerca de su composición en tanto software y por otro desde su expresión social con los humanos mediante la retroalimentación algorítmica, la interacción mediante interfases y desde las redes sociales como espacio de congregación de la interacción. Aquí se usarán datos recabados de segunda mano, extraídos por un lado de las plataformas Meta y Twitter, y por otro del Servicio Electoral de Chile (SERVEL), los cuales se sometieron a una revisión analítica acerca de los modos de expresión y cristalización de las plataformas publicitarias al interior de los procesos políticos ligados al plebiscito constitucional del año 2022.
Transformaciones del concepto de vejez a través de la historia: Un análisis desde la prehistoria hasta el envejecimiento activo
Authors: Yusta Tirado Rubén , Fernández-Roses Daniel , De Gea Grela Pablo , García-Aguña Sonia , Gallardo-Peralta Lorena Patricia
Published: January 2025

A lo largo de la historia las concepciones sobre la vejez han evolucionado y fluctuado, des-de visiones más negativas e, incluso, marginalizadas, a perspectivas más inclusivas y activas. En todo caso, la comprensión de la historia del envejecimiento es fundamental para, por un lado, contextualizar los enfoques actuales como son el enfoque biopsicosocial, que considera la interacción entre factores biológicos, psicológicos y sociales, o el modelo de envejecimiento activo, que promueve la participación plena en la sociedad. Y, por otro lado, para aproximarnos de forma más certera a las posibles necesidades específicas de las personas mayores en un contexto global de envejecimiento poblacional acelerado y sin precedentes. Todo ello, fomenta la reflexión sobre el diseño de políticas públicas y estrategias como las intergeneracionales, las cuales pueden promover un envejecimiento saludable, digno y participativo, y que deben estar adaptadas a la diversidad de las personas mayores, muchas ve-ces consideradas como una población homogénea.
Del Sol Naciente al Jaguar de América: Migración y transmisión cultural a través de las prácticas cotidianas de mujeres niponas en Santiago de Chile
Authors: Obilinovic León Xiomara , Garrido Alarcón Paulina
Published: January 2025

Este estudio se centra en el rol de las mujeres japonesas migrantes en la transmisión de su cultura en Chile. Se explora cómo, en un contexto socialmente patriarcal como el japonés, el trabajo de la mujer ha sido relegado al ámbito doméstico. El objetivo principal es entender las prácticas cotidianas de las mujeres niponas migrantes en Santiago de Chile, reconociéndolas como las principales transmisoras de su cultura de origen y como promotoras de espacios que facilitan procesos de hibridación en el diálogo intercultural con sus comunidades locales y la sociedad chilena. Asimismo, se investigan los desafíos que estas mujeres han enfrentado a lo largo de su trayectoria migratoria como portadoras de una cultura extranjera. Se emplea una metodología cualitativa, con entrevistas como herramienta principal, trabajando directamente con mujeres migrantes de origen japonés. Los resultados destacan la importancia de las mujeres en la preservación y transmisión cultural, a pesar de los cambios progresivos en los roles de género a lo largo del tiempo.
Aportes de la Bioética a la Formación de Profesores, de Educación Física, Deporte y Recreación
Authors: Romero Henry Caro
Published: January 2025

Objetivo: Realizar una contribución a la formación de profesores de Educación Física, Deporte y Recreación, desde la perspectiva de la bioética. Metodología: Cualitativa, se diseñó una entrevista ad hoc sobre: Formación humanista vs. Formación transhumanista, sopesando los principios bioéticos de Justicia y No Maleficencia. Resultados: La visión de la formación de los profesores entrevistados es humanista. La mayoría descalificó la propuesta transhumanista, porque no respeta el Principio Bioético de Justicia y podría vulnerar el Principio Bioético de No Maleficencia. Discusión: La formación transhumanista es aún lejana para el contexto colombiano y Latinoamericano. Es necesario difundir la bioética y sus principios.Palabras claves:
El fútbol, evento total: apuntes etnográficos sobre las identidades futboleras en Uruguay y Argentina
Authors: Diaz Francisco
Published: January 2025

El presente artículo busca indagar en las identidades futboleras en Uruguay y Argentina, explorando el rol del fútbol como fenómeno cultural en ambos países. Desde un enfoque socioantropológico, se analiza cómo el fútbol moldea identidades y valores, incidiendo incluso en el lenguaje cotidiano. Se exploran las preferencias de las personas futboleras respecto a sus clubes y selecciones, y se destaca la importancia del fútbol en la construcción de identidades nacionales y en la socialización cotidiana de los individuos. El estudio se realizó con métodos etnográficos multilocales y entrevistas en profundidad a hinchas y proyagonistas, observando cómo las redes sociales y la globalización inciden en estas identidades.
O acesso à cidadania e os usos políticos dos corpos na ciclovia de Aracaju/SE
Authors: Levoratti Alejo , Zoboli Fabio , De Oliveira Sayuri Silva Dantas
Published: January 2025

O presente estudo tem como objetivo interpelar o espaço público urbano da ciclovia de Aracaju e a segregação social em função dos descompassos provocados pelos fluxos neoliberais de produção de riqueza e manutenção/reprodução de pobreza. O escrito parte do pressuposto de que a ciclovia aracajuana é, em grande medida, antidemocrática, portanto, não pode ser vista como um quesito de cidadania. Para sustentar tal suspeita são tensionados alguns questionamentos: Para que atores sociais a ciclovia foi pensada enquanto política pública? Para que prática corporal urbana ela foi concebida? Para que tipo de corpos e bicicletas ela foi pensada? Em termos geopolíticos, qual a função da malha cicloviária de Aracaju? Entendemos que os usos dos corpos dos ciclistas são distintos na medida em que política e esteticamente usam suas bicicletas com diferentes objetivos. De igual modo, os processos de transmissão e utilização destas técnicas corporais são estruturados por questões de classe e de gênero. Conclui-se que embora tenha sido concebida como uma forma de construir qualidade de vida para os setores abastados, os usos dos cidadãos estão longe do que foi concebido e expresso e nela se materializam as desigualdades em termos de classe social e de género que a cidade moderna atravessa.
Una Aproximación a la Carrera Dual en Perú
Authors: Moreno-Peña Jorge David , Hammer Gonzalez del Riego Patrick Eduardo
Published: January 2025

En el contexto peruano, el aumento de deportistas que combinan sus carreras deportivas con estudios superiores ha generado la necesidad de investigar y comprender los factores que intervienen en este proceso. Este artículo usa una metodología descriptiva con enfoque documental para abordar los desafíos y factores intervinientes en la carrera dual de los deportistas peruanos, incluyendo aspectos psicosociales, vocacionales, académicos, deportivos y económicos. Se destaca la importancia del apoyo social, la flexibilidad académica, la gestión del tiempo y el acompañamiento psicológico como elementos clave para el éxito en la carrera dual. Además, se señala la falta de investigación previa en este ámbito en el contexto peruano y se propone un enfoque integrativo y una mayor intervención psicológica para mejorar el bienestar y el rendimiento de los deportistas que cursan estudios superiores.
Don’t make promises you can’t keep: Why hasn’t the gap closed?
Authors: Gunion Scott
Published: January 2025

The Independent Care Review acknowledged that the care system in Scotland was not working and culminated in the publication of The Promise, a commitment to improve the lives of Care Experienced (CE) Young People (YP). For schools, The Promise states that the formal and informal exclusion of CE YP must end. Scottish Government statistics indicate that although exclusions rates for CE YP have decreased over time, a consistent inequitable gap persists between rates of exclusion for CE YP and their peers (Scottish Government, 2012; 2022). The present research aimed to capture secondary school teachers’ experiences of exclusion regarding CE YP via semistructured interviews with seven secondary schools within one local authority in Scotland. The research aimed to explore what secondary schools experienced as supports, challenges, contributing factors, and alternatives to the exclusion of CE YP. The purpose of this research was to inform future practice for Educational Psychologists (EPs) and wider education professionals, and to highlight tensions between policy and practice regarding the exclusion of CE YP. Data gathered through the seven semi-structured interviews was analysed using Braun and Clarke’s (2006) six phase thematic analysis. The overarching themes developed through analysis were CE YP as part of their school, ethos around exclusion, alternatives to exclusion, challenges for schools, and CE YP treated differently. Secondary schools described supports as the approach used, relationship with CE YP, and ethos of no exclusion. Challenges related to staff welfare, tensions with the CE identity, and tensions between policy and practice. Contributing factors to the exclusion of CE YP were associated with major incidents, typically relating to violence and aggression. Implications for EP and wider educational practice are discussed.
Exploring the Intersection of Art, Human Creativity, and AI
Authors: Giorgetti Ilaria
Published: January 2025

Since the early 2000s, computational informatics has increasingly entered the artistic sphere, traditionally a human monopoly. Generative artificial intelligences follow creative processes that are seemingly similar to human ones: they learn from existing works, grasp stylistic canons, and ultimately generate a new artifact that is aesthetically pleasing. Some of them have passed the Turing test, which may lead to the claim that we have reached a point where machines are capable of thinking, feeling, and knowing, thus undermining human beings from their domain in art and all creative fields. However, this perspective of exalting computational creativity has several critical points that can be refuted through contributions from fields such as philosophy and neuroscience. Art and culture have a symbolic value that cannot be generated by computational processes: they help define the Umwelt through which humans experience the world; they reflect the worldview of an era and a society; they attribute meanings to existence and reality. Therefore, it is challenging to summarize a work of art through computational models, as it contains a dimension of meaning that goes beyond form and cannot be exhausted through the logic of language, words, or computer signs. Finally, creativity is a much more complex process than simple learning and reshuffling of data: it is an ontological characteristic of human beings and is the result of millennia of evolutionary processes, which have led humans to develop conscious minds that - through a complex relationship between sensory perception, neural networks, and emotions - enable reasoning and creative thinking. The case of musical composition illustrates the gap between human creativity and artificial creativity: computational algorithms are to be seen as new mediums that open up new expressive possibilities for artists, but they cannot completely replace the human element in the creative process.
Manajemen Projek Penguatan Profil Pelajar Pancasila Untuk Meningkatkan Karakter Peduli Lingkungan
Authors: Suyitno Suyitno , Sholeh Muhamad , Khamidi Amrozi
Published: January 2025

Character education in schools forms a responsible and ethical generation, as well as instilling awareness and behavior to care for the environment in a global and national context. This study aims to examine the Management of the Pancasila Student Profile Strengthening Project at State Junior High School 1 Kenduruan, Tuban Regency. This study uses a qualitative method with a case study approach to analyze the implementation of the Pancasila Student Profile Strengthening Project in building environmental care character. Data was collected through interviews, observations, and documentation analysis, then processed using condensation techniques, presentation, and conclusion drawn. The validity of the data is guaranteed through triangulation of sources and methods. The results of the study show that (1) Project Management for Strengthening the Pancasila Student Profile: Program management is carried out through the formation of a team of facilitators, designing theme dimensions, preparing teaching modules based on student needs, and implementing structured action-based learning to support the character of caring for the environment according to the vision of Adiwiyata School. Continuous evaluation is carried out using formative and summative assessments. (2) Impact of implementation: The implementation of the program increases students' awareness of environmental issues, practical skills in waste management, strengthening Pancasila values such as responsibility and mutual cooperation, and the creation of environmentally friendly habits that are oriented towards sustainability. The school gained recognition as an environment-based learning model. (3) Solutions to overcome obstacles: Strategies include teacher training, evaluation system modification, collaborative learning, resource optimization, and collaboration between schools to share best practices. Focus on the involvement of all elements of the school to ensure the sustainability of the program and the achievement of the vision of Adiwiyata School.
Simbolisme Onak Duri dan Mahkota Duri dalam Kejadian 3:18 dan Matius 27:29: Implikasi untuk Rencana Keselamatan Manusia
Authors: Goni Edwin Eldrich , Nainggolan Bartolomeus Diaz
Published: January 2025

This research aims to gain a comprehensive understanding of the symbolism of thistles and crown of thorns, the methodology used is qualitative, the author is actively involved in all stages of the research process, from defining the problem to reaching the findings. The research method used literature study with data processing procedures including interpretation and analysis of data to explain a more comprehensive significance of the Symbolism of Thistles and Crown of Thorns in Genesis 3:18 and Matthew 27:29: Implications for Human Salvation Plan. The results show that the symbolism of Jesus' crown of thorns reflects His faithfulness to God and His love for mankind, as well as His strength and dignity even in the midst of unjust suffering. The crown of thorns became one of the most powerful symbols in the Bible of Christ's sacrifice and suffering for the salvation of mankind.
Tinjauan Teologis Liturgi Pemindahan Tulang Pada Pemugaran Makam Bagi Suku Dayak Kristen
Authors: Angellyna Sri
Published: January 2025

The study in this research looks at the use of grave removal liturgy in the grave removal ritual for Christians at the GKE Sinta Petuk Liti congregation.  This research was conducted using a qualitative research approach with a descriptive type of research because the focus of this writing describes a research result with the aim of providing an explanation related to the phenomenon of grave removal worship using the grave removal liturgy, in which there is a bone washing ritual but carried out by Christian Dayaks. Data collection in this paper uses interviews, observation, documentation and literature study. Data analysis used in this writing includes data reduction, data presentation, and data conclusion drawing and verification. This analysis will help the author to see the theological review of the bone removal liturgy in the restoration of graves in Petuk Liti village for Christian Dayaks. The removal of graves for Christians in the GKE Sinta Petuk Liti congregation has meaning as a sign of respect and a way for families to express love for the deceased.