bluuebunny/crossref_metadata_2025 huggingface dataset:
An Alternative Option to Compression Hemostasis in Case of Esophageal Vein Bleeding in Patients with Portal Hypertension
Authors: Budarev Vadim , Fedoseev Andrey Vladimirovich
Published: July 2024

Introduction. Compression hemostasis is widely used to arrest bleeding from veins of the esophagus in portal hypertension. Since it has a number of severe drawbacks, research is relevant to develop new approaches to solve this problem.The aim of the study was to provide evidence and develop a technique to arrest bleeding from varicose veins of the esophagus, which can become an alternative to compression hemostasis.Materials and methods. The key technology in the study was chemical-mechanical hemostasis – the combined esophageal vein compression and Hemoblock application. At the first stage, this technique was tested on laboratory animals - domestic pigs, since a model of the esophageal vein bleeding was formed in their bodies. At the clinical stage, chemical-mechanical hemostasis was performed in 15 patients with the recurrent esophageal vein bleeding; they made up the experimental group. The control group consisted of 15 patients subjected to compression hemostasis. The hemostatic effectiveness of the techniques and their assessment by the patients themselves were compared in the study.Results. In the experimental group, bleeding was arrested in 46.7% of cases by installing a probe for chemical-mechanical hemostasis with a 5-minute exposure. In the control group, bleeding was arrested in 66.7% of cases by installing an obturator probe with a 10- to 24-hour exposure. As patients’ survey reported, in the control group, patients experienced pain during the insertion of the obturator probe in 86.7% of cases, and 20% of patients experienced pain during the entire time the obturator probe was in the esophagus; 93.3% of patients expected an early termination of the procedure, 13.3% claimed that they would never agree to the procedure again. As patients’ survey reported, in the experimental group, 6.7% of patients experienced pain when inserting the probe for chemical-mechanical hemostasis and during the time, it remained in the body. 46.7% of patients wanted the procedure to be terminated as soon as possible. There were no patients who refused to repeat a procedure of chemical-mechanical hemostasis if required.Conclusions. The study demonstrated that a modified conventional obturator probe, which allowed combining compression of the esophageal veins with the hemostatic drug effect, resulted in a significantly increased hemostatic effect in case of the esophageal vein bleeding. During the study, this technique prevented 46.7% of patients from the need to use an obturator probe. Since the obturator probe, when applied, causes a large number of troublesome and painful sensations (a fact reported by 93.3% of patients), even its partial elimination can be considered as an option improving the quality of the treatment.
Necrotizing Soft Tissue Infection Management: a Clinical Case Study
Authors: Sukovatykh Boris Semyonovich , Blinkov Yuri Yurievich , Zaitsev Ilya Alexandrovich , Zuev Yuri Sergeevich , Pashkov Vyacheslav Mikhailovich
Published: July 2024

Necrotizing soft tissue infection is a rare (0.4 cases per 100,000 population) but very severe pathology with a mortality rate up to 10%. The paper presents a clinical case of successful management of necrotizing soft tissue infection of the right arm, lateral wall of the chest and abdomen. The dynamics of the wound process was controlled by clinical, bacteriological, X-ray and ultrasound examinations. The cause of necrotizing soft tissue infection in this patient was the associated anaerobic nonclostridial and aerobic flora. Numerous surgical interventions were used to manage the patient; they were aimed at the excision of the necrotic tissue at the start of treatment, plastic surgery of postoperative wounds with local tissues was used at the end of treatment. The progression of the necrotic process was stopped after the third intervention. In addition to surgical treatment, the patient received antibacterial, detoxification, and immunostimulating therapy. Despite numerous staged surgeries with the excision of the necrotic skin, subcutaneous fat and fascia, it was possible to completely restore the patient’s ability to work.
A Review on Novel Methods of Pharmacology Teaching Concerning Iranian Academic Context
Authors: Shooraj Mahdi , Fekri Kiarash , Mousazadeh Noushin , Mahdavi Seif Ali
Published: July 2024

Pharmacology is the cornerstone of health science courses the same as biomedical programs in educational setting. New educational intuitions and methodical progresses in teaching and learning, as well as recent findings in pharmacology research, can help pharmacology educators reconsider and regulate their teaching approaches. Thus, the aim of this article is to review existing studies on the different methods of teaching pharmacology and investigate different outcomes in this regard. In the present investigation, recent articles in the databases of Web of Science, PubMed, Scopus, Embase, Google Scholar, IranDoc and Scientific Information Database (SID) were examined, and the delegated documents were reviewed. The gathered data showed that students’ cognitive, metacognitive, and cooperative learning besides collaborative skills are effective factors for teaching. Additionally, application of blended learning or flipped instruction via technologies such as computer ameliorates the process of teaching and learning pharmacology in academic setting. Consequently, to overcome the difficulties in managing the data overload, it sounds necessary to introduce new teaching methods in academic context. Therefore, the current investigation is useful for practitioners, curriculum designers and educational administrators in medical and paramedical educational context.
Upright Versus Recumbent Position in the Second Stage of Labor for Women With Epidural Analgesia: A Randomized Clinical Trial
Authors: Shahriari Ali , Nataj-Majd Masoomeh , Akrami Majid , Khooshideh Maryam , Soleimani Mahsa
Published: July 2024

Epidural analgesia (EA) is an effective and common method of pain relief during labor. However, EA may also have some adverse effects like prolonged labor, increased risk of operative delivery, and some unwanted complications. It's unclear how maternal position affects the outcomes of natural birth with EA. This study aimed to compare mode of delivery and maternal and neonatal outcomes between recumbent and upright positions in nulliparous women with EA. This randomized clinical trial involved 540 women who received EA at cervical dilatation of 4 to 6 cm. During the second stage of labor, they were instructed to adopt upright or recumbent position. The main outcome was the mode of delivery. The secondary outcomes included duration of labor, pain intensity, the Apgar score, and other maternal and neonatal complications. Finally, 528 women were included in the final analysis. The upright group had a higher rate of cesarean section than the recumbent group. The duration of the labor stages did not differ between the groups. The pain intensity in the second stage was higher in the upright position. The Apgar score at 1 and 5 minutes was higher in the recumbent group. There was no difference in terms of other outcomes between the groups. Recumbent positions are beneficial in the case of rate of cesarean, mother’s pain, and Apgar score in women with EA. So, adopting a recumbent position during the second stage of labor may be preferable for women with EA.
Erythrocyte Antioxidants and Hexokinase Activity Alterations in CCl4-Induced Cirrhotic Rats Through Naltrexone Treatment
Authors: Kholari Fatemeh Sarhadi , Nourbakhsh Mitra , Shekarkhar Golsa , Dehpour Ahmad Reza , Golestani Abolfazl
Published: July 2024

Cirrhosis is the consequence of chronic liver injury Considering the crucial role of oxidative stress in the progression of liver cirrhosis, we aimed to investigate the ameliorative effect of NTX against oxidative stress in carbon tetrachloride (CCl4)-induced cirrhotic rats. Eighty-four male Wistar rats were randomly assigned into 4 groups (21 rats /group I) receiving CCl4; (II) NTX+CCl4; (III) mineral oil (M) (as the control); (IV) NTX+M. The animals in each group were sacrificed in 3 different time-points 2 weeks, 6 weeks (early cirrhosis) and 8 weeks (advanced cirrhosis). Liver function tests, NO metabolites, GSH level, as well as the activity of antioxidant enzymes including superoxide dismutase (SOD), catalase (CAT), glutathione peroxides (GPX), and hexokinase (HK) were assessed. NTX was able to ameliorate liver injury, revealed by attenuation of ALT activity, which was significantly enhanced due to cirrhosis induction, as well as pathological evaluation. HK was also increased significantly after treatment with CCl₄ while NTX moderated this increase. Although CCl4 treatment did not have a significant effect on GSH levels, NTX was able to considerably increase GSH in blood. The activity of CAT and SOD as well as NO levels were all augmented by NTX in CCl4-treated rats. Naltrexone demonstrates antioxidative effects in liver cirrhosis and may confer a protective effect against hepatic cirrhosis through modulation of oxidative stress.
An Overview on Prevalence and Detection Approaches of BRAF V600E Mutation in Anaplastic Thyroid Carcinoma: A Systematic Review and Meta-Analysis
Authors: Behnagh Arman Karimi , Eghbali Maryam , Abdolmaleki Fereshteh , Ghadikolaei Omolbanin Asadi , Rezazadeh Asl Parisa , Afsharpad Mandana , Cheraghi Sara , Honardoost Maryam
Published: July 2024

Background: BRAF V600E mutation is proved critical in the progression and invasion of thyroid cancer, and as a prognostic biomarker. As anaplastic thyroid cancer (ATC) is a rare and aggressive form of thyroid cancer, this study was conducted to provide a view on prevalence of BRAF V600E as well as the best molecular diagnostic method in ATC patients.
Methods: A comprehensive literature search was performed from their inception to Oct 2022 in PubMed, Scopus, Google Scholar, and Web of Science (WoS). The data of the prevalence of ATC were extracted. Moreover, the diagnostic feature of the available diagnostic tools was extracted to measure the sensitivity and specificity. To pool the prevalence data, we used meta-proportion analysis and diagnostic meta-analysis was conducted to determine the specificity and sensitivity of the immunohistochemistry method in detecting BRAF V600E mutation among patients with ATC.
Results: Overall, 34 studies were included in this meta-analysis. The incidence of BRAF V600E was shown 33% in the 978 patients. The sensitivity and specificity of IHC in detecting BRAF V600E were detected 78.9% (95%CI: 60.1-97.2), and 69.7% (95%CI: 41.2-98.1), respectively.
Conclusion: IHC had an acceptable prognostic profile for detecting BRAF V600E in ATC patients. The diagnosis of BRAF mutation is critical in clinical trials and may be helpful for choosing proper-targeted therapy strategies in ATC patients.
The Performance of the Current Algorithm of HIV Diagnosis
Authors: Gulmez Abdurrahman , Appak Ozgur , Zeka Arzu Nazli , Esen Nuran , Sayiner Ayca Arzu
Published: July 2024

Background: We aimed to evaluate the performance of the current algorithm the HIV diagnosis that has been performed for four years. Results of HIV Ag/Ab tests, anti-HIV 1/2 confirmatory tests, HIV-1 RNA tests and the time for official results to be approved were evaluated.
Methods: The relationship of HIV Ag/Ab tests, anti-HIV 1/2 confirmation tests and HIV-1 RNA PCR tests, their result times and suitability to the algorithm were examined at Izmir Dokuz Eylül University between May 2017 and June 2021.
Results: HIV Ag/Ab ELISA was reactive repetitively in 165/54628 (0.30%) serum samples. Anti-HIV 1/2 confir-mation test was reactive in 54.42% (80/147) of samples. The most common pattern (18.2%) in the con-firmation tests was the positivity of the antibodies against gp160 - gp41 envelope glycoproteins together. The mean reporting time of the confirmation test result was 3h 50 min after the ELISA test. The mean reporting time of the HIV-1 RNA PCR was 12.79 d (±10.22) after the ELISA test and 12.63 (± 10.12) day after the confirmation test. In ROC analysis, the estimated rate of the ELISA test for the confirmation test was highest when S/CO was >13.16 (sensitivity: 97.59 %, specificity: 97.59%).
Conclusion: The confirmation test in the current algorithm enabled the rapid test results, early diagnosis of HIV and early antiretroviral therapy. To use the new algorithm effectively, decentralization of the validation tests would be appropriate.
Disinfection of Medical Solid Waste through the Application Ozone Technology: Feasibility and Effectiveness Study
Authors: Ghozikali Mohammad Ghanbari , Vejdani Nasrin , Dehghanzadeh Reza , Taghipour Hassan
Published: July 2024

Background: We aimed to determine the feasibility of ozone for disinfection of infectious solid waste in hospital.
Methods: Spores of Bacillus atrophaeus were used to monitor the process of inactivating microbial agents using ozone in medical solid waste in the hospitals of Tabriz City, Iran. For this purpose, culture medium containing the mentioned bacteria was placed in the bags containing medical wastes. The ozone generator was equipped with a constant dose of 5 grams per liter, with a discharge of 1 and 3 liters per minute and contact time of 10 to 120 min. Then the ozone exposure indicators were incubated for 24-48h at 36 ± 1 °C and, finally, the absence of colony growth in the culture medium was considered as the success of ozone in disinfection of infectious solid waste. This process was performed with 4-time replications.
Results: The complete removal of B. atrophaeus was obtained for non-compacted and compacted infectious solid waste, at contact time of 15 and 50 min, respectively. The efficiency of removal of B. atrophaeus by the process of wet ozone injection through a glass column was 100% in 30 minutes and by separate injection of water vapor into the contact tank was 100% in 50 minutes. The results of this study showed that the use of ozone technology was effective in the inactivation and destruction of microbial agents in medical solid waste.
Conclusion: Employing different advanced technology of oxidization especially ozone in order to decrease the environmental pollution is considered as one of management approaches.
The lncRNA UCA1 Enhances Pancreatic Cancer EMT by Regulating miR-708-5p and miR-135b-5p: A Bioinformatics Approach
Authors: Askari Nahid , Pirouz Marziye Shad , Mafikandi Vida , Hadizadeh Morteza , Mousavi Seyedeh Zahra
Published: July 2024

Background: Pancreatic cancer (PC) is an exceedingly malignant ailment that is not only characterized by its insidious onset and rapid progression but also by its poor therapeutic effects. Recently, emerging evidence has shed light on the significant role that non-coding RNAs (ncRNAs), particularly long ncRNAs (lncRNAs) and microRNAs (miRNAs), play in the pathogenesis of PC. This investigation aimed to construct a network of interactions between miRNAs, lncRNAs, and mRNAs, as well as to perform correlation analyses in the context of PC.
Methods: This study carried out in Kerman City, southeastern Iran in 2023. We utilized the GSE119794 dataset from the Gene Expression Omnibus (GEO) to analyze differentially expressed lncRNAs (DE-lncRNAs), miRNAs (DE-miRNAs), and mRNAs (DE-mRNAs). Following the identification of the DE-lncRNAs, DE-mRNAs, and DE-miRNAs, we proceeded to examine differentially expressed epithelial-mesenchymal transition (EMT) genes. Subsequently, we utilized the RNAInter database to predict interactions among lncRNAs, miRNAs, and mRNAs. Finally, we employed Cytoscape to visualize and analyze the constructed network.
Results: 14 DE-lncRNAs, 14 DE-miRNAs, 545 DE-mRNAs, and 65 DE-EMT from pancreatic cancer and its adjacent tissue RNA-Seq data were identified. 1184 EMT genes from dbEMT were obtained, among which 65 DE-EMT were assigned as EMT genes and correlated with tumor progression. One functional lncRNA (UCA1) was identified as a key functional lncRNA. The area under the ROC curve (AUC) of UCA1 and miR-708-5p were 0.79 and 0.86, respectively. Thus, it is reasonable to believe that this prognostic risk model helps predict PC metastasis.
Conclusion: UCA1 is a new lncRNA linked with EMT in PC and contributes to a better knowledge of the regulatory mechanisms related to lncRNAs in PC.
Self-Care of Adolescent Girls in Puberty: A Missing Need in the Health SystemSelf-Care of Adolescent Girls in Puberty: A Missing Need in the Health System
Authors: Kiani Zahra , Simbar Masoumeh
Published: July 2024

The Article Abstract is not available.
Psychological Consequences of Experiencing Child Min Girls
Authors: Meghdadi Fatemeh , Khanjani Mahdi , Eskandari Hossein
Published: July 2024

Aim: The research aimed to study the psychological consequences of child marriage among girls through a phenomenological approach and semi-structured interviews. Methods:  Twenty women from Gilan, Khoozestan, Sistan and Baloochistan, Khorasan and Yazd province who experienced child marriage and their current ages were less than 50 years old were selected through purposive sampling. Interviews and observations were conducted by traveling to each province. Colaizzi method was used in order to analysis data. Results: Results were included of 5 main themes and 15 sub themes in psychological consequences. Main themes are crashed ego, psychic traumas, negative emotions, immaturity and personal maturity. Conclusion: The results showed that negative psychological consequences of child marriage are much more than their positive ones.
Identifying Women's Positive Live Experiences of Motherhood
Authors: Sengdeh Javad Khodadadi , Ghahremani Mutlaq Fatemeh , Ebrahimi Fariba
Published: July 2024

Aim: The period of parenthood is considered an important period in life; aAt this time, we see changes in various dimensions in parents. The aim of this study was to identify changes in personal, marital and social dimensions. Methods: This qualitative research was conducted using thematic analysis approach. The study population of the research is equal to the research participants, were included couples who have been married for at least 7 years and have at least one 2-year-old child; have comparative satisfaction with their lives; residein Tehran and participated in the research with informed consent. The participants were selected from the eligible clients through purposive sampling and available methods. The sampling process continued until theoretical saturation was reached and finally 18 participants were studied through interviews. Results: The thematic analysis of the data showed that mothers believe that since the birth of a child, they had increasing changes in personal, marital and social relationships; So that the personal dimensions include: the expansion of responsibility, the expansion of self-concept and patience. Also, the trends that we witness in the marital relationship include intimacy, enriching couple cohesion, strengthening boundaries and creating parental identity, and the trends in social relationships include revising the social role and expanding the bond with the family of origin
Attachment-Based Family Therapy for Transgender Adolescent with Suicidal Thoughts: A Case Study
Authors: Abbaspour Zabihollah , Vasel Golshan , Jahanbin Fatemeh , Beni Mina Ahmadi , Charkhab Narges
Published: July 2024

Aim: The aim of present study was the application of the Attachment-Based Family Therapy (ABFT) for a transgender adolescent with suicidal thoughts. Methods: Multiple baseline experimental single case study was used as the method of the present study. The population sample is a transgender adolescent (female to male) and his/her parent chosen according to the purposive sampling method. The adolescent completed The Suicidal Ideation Scale (SIS) over the course of the sessions. ABFT was implemented in twenty-seven 90 minute-sessions. Furthermore, visual inspection is applied to analyze and interpret data. Results: The results of this qualitative and step-by-step investigation of the attachment-based family therapy showed that this therapy was effective in significantly reducing the suicidal thoughts in the transgender adolescent. Conclusion: Effective intervention with transgender adolescents and their families can foster a secure attachment relationship. Family therapists may employ attachment-based family therapy to address suicidal tendencies among transgender individuals. This approach also supports families in navigating the transformative journey of their transgender child.
The Mediating Role of Marital Intimacy in Relation with Midlife Crisis with a Tendency toward Infidelity in Middle-Aged Men
Authors: Taziki Zahra , Choobforoushzadeh Azadeh , Rezapour Yaser
Published: July 2024

Aim: The purpose of this study was to investigate the role of marital intimacy in relation between midlife crisis and the tendency to infidelity in middle-aged men. Methods: This was a correlational research with structural equation modeling method. The statistical population of this research was made up of all men aged 40 to 60 in Razavi Khorasan province, 200 of whom were selected by convenience sampling and answered the questionnaires of marital intimacy, mid-life identity crisis, and tendency to infidelity. Data analysis was done using structural equation method using SPSS and AMOS softwares. Findings: The results of this research showed that the assumed model has a good fit. Also, the results of the analysis indicated a direct relationship between the tendency to infidelity and the midlife crisis, and there was an indirect relationship between the midlife crisis through marital intimacy on the tendency to cheat. Also, marital intimacy has an inverse and significant relationship with the independent variable of the midlife crisis, as well as marital infidelity. It has a direct and significant relationship with midlife crisis, and there is an inverse and significant relationship (-0.643) between marital infidelity and marital intimacy. Conclusion: Therefore, it can be concluded that marital intimacy has been able to play a mediating role between midlife crisis and the tendency toward infidelity. So, marital intimacy and midlife crisis can play an influential role in married life and the tendency of people to commit marital infidelity. Therefore, it is necessary to provide appropriate knowledge and training to couples who are exposed to these injuries.
Enhancing Plant Disease Detection through Transfer Learning by Incorporating MemoryAugmented Networks and Meta-Learning Approaches
Authors: C Dr. Mohana Priya
Published: July 2024

Transfer learning has revolutionized automated plant disease detection by leveraging pre-trained convolutional neural networks (CNNs) on large-scale datasets like ImageNet. This paper explores advanced methodologies in transfer learning, focusing on the integration of memory-augmented networks and meta-learning approaches. These enhancements aim to improve model adaptation to new disease types and environmental conditions, thereby enhancing accuracy and robustness in agricultural applications. The paper reviews existing literature, discusses methodologies, and suggests future research directions to advance the field of AI-driven plant pathology.
Impact of River Water Pollution on Rice and Wheat Productivity: A Case Study in Maharajganj District, India
Authors: Jatav Surendra Singh , Bharati Nathoo , Nayak Sanatan
Published: July 2024

Background: Increased water pollution is a worldwide problem that threatens the well-being of billions of people and their economies, ecosystems and quality of life in both developed and developing nations. Poor wastewater management has exacerbated major water-quality concerns in many regions of the globe, increasing the water crisis. With these, the present study made an attempt to capture the impact of river water pollution on rice and wheat productivity in surveyed villages in Maharajganj district, Uttar Pradesh, India. Methods: A field survey of 200 farmers was conducted from (1-30/September/2021) using multistage sampling. Further, the productivity change method was used to calculate the impact of river water pollution on crop productivity. Result: The results from this study show that per acre rice and wheat crop productivity was 8.84 and 7.78 quintals in Rajabari village (a river pollution-affected village) respectively, while the corresponding figures in Taraini village (a non-river pollution-affected village) were 19.86 and 18.14 quintals/acre. Further, net returns for rice and wheat crops in Rajabari village were Rs. 4863 and Rs. 5730, while corresponding figures in Taraini village were Rs. 19319 and Rs. 22070 per acre, respectively. Hence, the present study recommends that the government should take appropriate water contamination measures to limit water pollution through appropriate treatment methods. To prevent contamination of water containing with heavy metals, petroleum hydrocarbons, detergents and any pollutant that causes danger to the environment and in order to achieve normalcy within the limits of standards, attention should be focused on the prevention of water pollution with pollutants and the preservation of the quality and ecosystems of these waters through adequate and uninterrupted monitoring in time and space.
Prevalence of Bacterial Diseases in Ornamental Fish Rearing Units of Kolathur, Tamil Nadu, India
Authors: Srinath R. , Uma A.
Published: July 2024

Background: Ornamental fishkeeping is a widely embraced hobby globally. In India, Kolathur, Chennai Tamil Nadu is an important ornamental fish hub involved in trading of ornamental fishes. As a lucrative industry, the ornamental fish trade faces significant challenges due to diseases caused by various pathogens, impacting market value and causing economic losses. Methods: A surveillance study was conducted in Kolathur, Chennai, from December 2022 to August 2023. Ornamental fish samples exhibiting clinical signs of bacterial diseases were collected from the farms and retail outlets. Bacterial isolation and identification techniques, including conventional and PCR detection, were employed to isolate and identify bacterial strains from infected fish samples. Result: Out of 196 fish samples, 51 (29.4%) were found infected with bacterial pathogens. The prevalent bacterial pathogens included Aeromonas veronii (47%), A.caviae (17%), Pseudomonas aeruginosa (15%), Streptococcus sp. (11.3%), Mycobacterium fortuitum (5.6%) and Shewanella sp. (3.7%). Different fish families exhibited varying susceptibility to bacterial diseases, with cyprinids being the most affected (56.6%). The findings stress the importance of adhering to health regulations to prevent transboundary spread and suggest the development of targeted management strategies to sustain the health of ornamental fish populations.
Detection of Disease in Calves using Artificial Intelligence
Authors: AlZubi Ahmad Ali
Published: July 2024

Background: Livestock farming is experiencing a digital transformation and is becoming more information-driven. However, this type of data is often kept in separate storage towers, making it incapable of practicing its potential to boost animal welfare. Lumpy Skin Disease (LSD) is a serious threat to the health of cattle worldwide and has caused financial problems for many cattle farming enterprises. It has been shown that combining machine learning (ML) and artificial intelligence (AI) with biosensor data and conventional visual inspections can improve the identification and diagnosis of this serious condition. Methods: This study presents an extremely precise livestock farming framework that combines data streams from a wide array of disciplines of dairy cattle to see if ever wider/vast data sources enhance the overall projections for diseases and if using the more complicated prediction models can reimburse for less diverse data to some extent. Using images from the farming landscape, this study highlights the utility of convolutional neural networks (CNNs) in the identification of the Lumpy Skin Disease Virus (LSDV) in animals. Result: An analysis of the relative weight given to individual factors in predicting accuracy shows that disease in dairy cattle results from the intricate interactions between many life domains/parameters, such as housing, nutrition and climate; that prediction performance is enhanced by incorporating a wider range of data sources; and that current information can be repurposed to produce useful information for vaccine development. The study highlights the potential of data-driven dairy interventions, focusing on artificial intelligence for disease prediction in cattle, to improve animal welfare and reduce the risk of disease. A Convolutional Neural Network (CNN) based model effectively classified skin conditions with an overall accuracy of 73.89% after 27 training epochs. This study demonstrates CNN’s useful applications in the field of veterinary medicine by highlighting its potential for early detection of Lumpy Skin Disease (LSD).
Lumpy Skin Disease Detection in Cattle by a Robust Approach using Advanced Convolutional Neural Networks
Authors: AlZubi Ahmad Ali
Published: July 2024

Background: Lumpy skin disease (LSD) is a significant health concern for cattle globally and poses economic threats by affecting various aspects of cattle health. Integrating artificial intelligence (AI) and machine learning (ML) with visual inspections and biosensor data has shown promise in enhancing disease detection and diagnosis. The present study harnesses the potential of Convolutional Neural Networks (CNN) and image processing for detecting LSD. Methods: Using images from the agricultural landscape, this study highlights the significance of convolutional neural networks that identify the lumpy skin disease (LSD) in animals. Images are categorized into two groups: LSD (infected skin) and non-LSD (normal skin). This is achieved by applying a deeply designed deep learning model carefully built to fulfill this particular need. Evaluation metrics assess the model’s performance, including accuracy, loss and a confusion matrix. Result: A CNN-based model trained for 50 epochs to classify skin conditions, achieved an 86.54% accuracy. The study underscores the potential of CNN in early LSD detection, paving the way for practical applications in veterinary medicine. Future work involves addressing dataset limitations, refining model parameters, reducing image noise, exploring different feature extraction methods and investigating additional animal skin conditions.
Protective Effects of Teucrium polium Leaves Ethanolic Extract against Eimeria papillata-Induced Behavioral Changes in Mice
Authors: Maodaa Saleh , Al-Quraishy Saleh , Abdel-Gaber Rewaida , Alatawi Afaf , Alawwad Sarah , Alhomoud Dalal , Al-Shaebi Esam
Published: July 2024

Background: Medicinal plants that are abundant in physiologically active phytochemicals have long been used in traditional medicine. Due to their anti-inflammatory and antioxidant qualities, several of these can lower the chance of developing certain illnesses. Coccidiosis is a disease that affects many animals and results in large financial losses. Eimeria spp. strains that are resistant to drugs have emerged as a result of drug addiction and overuse. Therefore, Teucrium polium leaves ethanolic extract (TPLE) was assessed on behavioral performance for the animals injected with Eimeria papillata. Methods: T. polium leaves ethanolic extract (TPLE) was prepared. Also, the behavior of mice infected with the E. papillata parasite and treated with the plant extract was evaluated. In addition, eosin and hematoxylin-stained tissue sections of mice brains were made. Result: There was an improvement in the number of vertical and horizontal movements in the plant-treated group. In addition, there was an improvement in learning and memory through increased total latency time the number of crossings during the shock. Also declined the number of inertial crossings and several reinforced crossings during the shock. There were no changes in oxidative stress or brain histopathology. Our results showed that TPLE has improved the behavioral performance of mice, which promotes the conduct of numerous researches on the compounds found in plants and their effect on animal behavior and also in investigating the behavior of animals in response to infection and treatment.
The Antecedent of Nurses’ Revenge and Gossiping Behaviors: Gender Microaggression Experiences
Authors: Boz Semerci Anil
Published: July 2024

Background and Purpose:Microaggressions that are not intended to cause deliberate harm to the target are frequently encountered in health communications. Individuals who are the targets of microaggressions may develop emotional and behavioral responses as coping strategies. This study seeks to provide needed clarity on the relationship between microaggression, gossip, and revenge.Methods:A quantitative method was used to collect data. Nurses working in public hospitals in Turkey participated in this study and provided valuable data for the final analysis and the acquisition of conclusion.Results:The findings indicated that the increasing effect of gender microaggressions on organizational gossip occurred both directly and indirectly through vengeful feelings. Moreover, the indirect impact of gender microaggression through revenge was moderated by gender.Implication for Practice:Given the subtle and ambiguous nature of microaggression, this study develops the implications of gender microaggression within emotional and behavioral constructs and has explanatory contributions through the development of direct and indirect relationships.
Unwanted Pursuit Behavior Victimization as a Predictor of Engagement in Nonsuicidal Self-Injury
Authors: Lietzau Stephanie B. , Dardis Christina M.
Published: July 2024

While prior research has studied associations between child abuse and nonsuicidal self-injury (NSSI), there is limited research assessing unwanted pursuit behavior (UPB) victimization and NSSI. In addition, few studies have assessed the self-reported functions of NSSI among survivors of violence. Among a sample of 18–25-year-old young adults (N= 333), both UPB victimization and child abuse were significantly associated with NSSI frequency. In regression models, UPB victimization was associated with increased use of affect regulation, antidissociation/feeling-generation, self-punishment, and antisuicide functions, while child abuse was associated only with antidissociation/feeling-generation and self-punishment. Affect regulation mediated the association between UPB victimization and NSSI frequency, but not the association between child victimization and NSSI frequency. Implications for research and clinical practice will be discussed.
KORUPSI DALAM PANDANGAN EKONOMI ISLAM
Authors: Kencana Ulya
Published: July 2024

Corruption is a phenomenon that gave negative implications for human life, both countries have developed and in developing countries. The issue of corruption to get serious attention from social scientists believed many fields because of corruption as the abuse of power, authority, and embezzlement and bribery significant deviation from the implementation of the value of the trust. Fairness is an important element in the matter of law and law enforcement so no wonder that the Qur'an emphasizes that justice be established though the relatives, even to yourself.
EMPOWERING SOCIALPRENNEUR DENGAN PENDEKATAN HOLISTIK ASMA’UL HUSNA: SPIRIT MANAJEMEN PEMBERDAYAAN SOCIALPRENNEUR DALAM MENGASAH SOCIAL INTELLEGENCE
Authors: Sarip Muhammad , Sumantri Rinol
Published: July 2024

Analisis diskriptif yang digunakan untuk menilai suatu Praktik Bisnis Indomaret dan Alfamart dikecamatan Danurejan sehingga dapat menghasilkan Prilaku Bisnis yang sesuai dengan Etika Bisnis Islam dimasa mendatang. Praktik bisnis Indomaret danAlfamart dikecamatan Danurejan dengan menggunakan analisis diskriptif akan menghasilkan informasi tentang praktik bisnis Indomaret dan Alfamart dikecamatan Danurejan apakah sudah sesuai dengan etika bisnis atau tidak, dalam penelitian ini difokuskan pada analisis praktik bisnis dan etika bisnis Islam. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana praktik dan etika bisnis Islam serta bagaimana praktiknya bagi para pelaku usaha bisnis Indomaret dan Alfamart. Penelitian yang dilakukan berupa analisis deskriptif. Instrument yang digunakan dokumentasi, interview, observasi dan kuesioner. Analisis yang dilakukan dengan membuat sintesi dan informasi-informasi yang diperoleh dari berbagai sumber ke dalam diskripsi yang berjalin mengenai yang peneliti amati atau yang ditemukan. Hasilnya menunjukkan bahwa Indomaret dan Alfamart di Kecamatan Danurejan Yogyakarta masih terdapat kecurangan-kecurangan di dalam praktiknya dan melanggar Undang-undang perlindungan konsumen. Dalam menjalankan usaha dan kegiatan bisnis, Indomaret dan Alfamart di kecamatan Danurejan belum banyak memahami dan mempraktikan prinsip atau nilai-nilai Islam dengan berlandaskan pada Al Quran dan Hadis. Praktik dan etika bisnis Islam ini meliputi lima prinsip dasar etika bisnis Islam: Unity (kesatuan), Equilibrium (Keseimbangan), Free Will (Kebebasan Berkehendak), Responsibility (Tanggung Jawab), dan Benevolence (Kebenaran).
Approaches to human resource management in the Arctic zone of Russia and circumpolar countries of Europe
Authors: Milaeva T.
Published: July 2024

The article presents an overview of approaches to human resource management in the Arctic zone of Russia and the circumpolar countries of Europe. The importance of high-quality human resources for the sustainable development of the circumpolar zone of Russia is considered, modern human resource management practices in Russia and European countries with territories beyond the Arctic circle are studied. All these countries need to attract, motivate, improve the skills and control the working staff. At the same time, their approaches to human resource management are not the same. The main differences are due to cultural factors, peculiarities of legislation, the economic situation in the country, the system of relations with employees, etc.
Tax treatment features of the mineral resources development: world and domestic experience
Authors: Burceva I.
Published: July 2024

Building a balanced system for obtaining a fair share of resource rents is one of the central objectives for the governments in the countries, rich in mineral resources. The special attention is paid to the high-margin projects on extraction of the hydrocarbon raw materials. Thus, the state share in the exploitation of its natural resources includes a variety of components, type and scope of which are determined by the specific conditions of a mining project. The article reviews the main tax instruments used in development of the mineral deposits, also considers the main trends in development of the international tax systems and their reflection in the Russian practice. It is shown that the main directions of the fiscal policy include simplification and striving for simplicity of administration, transparency in contracts between investors and governments, focus on transfer price issues, transition from gross royalties to taxation of economic results. Peculiarities of the budget policy in Russia determine development of agreements between the governments of the mining regions and mining companies aimed at the infrastructure and social facilities development, as a form of indirect natural rents for the development of the territories and local communities.
Comparative Studies of Tax Administration on Transfer Pricing
Authors: Aulia Sandra
Published: July 2024

Abstract
Transfer pricing practices are employed for tax avoidance by shifting profits through transactions with related parties. This study aims to provide recommendations for Indonesia's transfer pricing tax administration by examining the transfer pricing practices of Australia, the United Kingdom, the United States, China, Japan, Singapore, and South Africa. This research adopts a qualitative approach using literature review and descriptive statistics from the countries included in the study sample. The findings of this study indicate ten considerations for reconstructing transfer pricing administration: tax authorities should have relevant and reliable comparable data, collaborate with other entities to acquire comparable databases, optimally utilize the Automatic Exchange of Information for Country by Country Reports, leverage technology, enhance the skills of the tax authority and taxpayer personnel, establish an Alternative Dispute Resolution, consider using profit split method, promptly resolve transfer pricing issues and disclose Advance Pricing Agreement data, implement safe harbor rules, and educate taxpayers on transfer pricing regulations.
 Keywords: tax administration, tax avoidance, transfer pricing.
 
 
 
Abstrak
 Praktik transfer pricing dilakukan untuk penghindaran pajak dengan pergeseran laba melalui transanksi dengan pihak yang memiliki hubungan istimewa. Penelitian ini bertujuan untuk memberikan rekomendasi administrasi pajak atas transfer pricing di Indonesia dengan melihat praktik transfer pricing yang dilakukan Negara Australia, Inggris, Amerika, Cina, Jepang, Singapura, Afrika Selatan. Penelitian ini menggunakan pendekatan kualitatif dengan menggunakan studi literatur dan statistik deskriptif dari negara-negara yang dijadikan sampel penelitian. Hasil dari penelitian ini menunjukan 10 pertimbangan dalam rekonstruksi administrasi transfer pricing yaitu otoritas pajak  harus memiliki data pembanding yang relevan dan handal, menjalin kerjasama dengan entitas lain dalam perolehan database pembanding, memanfaatkan secara optimum Automatic Exchange of Information untuk Country by Country Report, memanfaatkan teknologi, meningkatkan keterampilan sumber daya manusia otoritas pajak dan wajib pajak, memiliki Alternative Dispute Resolution, mempertimbangkan penggunaan metode transfer pricing profit split, penyelesaian segera masalah transfer pricing dan mengungkapkan data Advance Pricing Agreement, menerapkan safe harbour dan mengedukasi pengetahuan wajib pajak atas aturan transfer pricing.
Kata kunci: administrasi pajak, tax avoidance, transfer pricing
Reflections on the Kerala Public Health Act 2023: A response to the commentary by S. Karpagam
Authors: Fernandez Bhavya , Jithesh Veetilakath , TS Anish
Published: July 2024

In this response, the observations of Karpagam S have been supplemented and repudiated using an understanding of the Kerala Health system and the general purpose of the Kerala Public Health Act (KPHA). The KPHA was crafted with a greater focus on a one-health and preventive approach. It does not seek to interfere in an individual’s preferred choice of treatment, except in the case of Public Health emergencies. KPHA is not a standalone document, but a supporting tool to the existing Kerala Health Policy and various other health policies and programs instrumental in improving the health and quality of life of the people of the State. The KPHA is intended to be an enforcement tool for legal provisions to ensure welfare maximisation of the society at large, and thus detailed discussions regarding actions to be taken beyond these legal provisions do not fall within the purview of the Act.
KPHA 2023 should explicitly include state accountability: Response to Fernandez et al
Authors: Karpagam Sylvia
Published: July 2024

The commentary “Public health ethics and the Kerala Public Health Act, 2023" published on January 27, 2024 in the Indian Journal of Medical Ethics (IJME) has received a response from members of the State Health Systems Resource Centre and Government Medical College, Malappuram, Kerala. They explain that the Kerala Public Health Act (KPHA) is a legal document and not required to explicitly include accountability mechanisms and social obligations of the state. Given the very real danger of state over-reach as was evident during the Covid pandemic, these checks and balances should, in fact, be non-negotiable. The position of KPHA on healthcare of migrant workers and patients with tuberculosis goes against existing public healthcare principles. There is therefore a need to revisit the Act to explicitly include state accountability.
Maceration duration and grape variety: key factors in phenolic compound enrichment of Montenegrin red wine
Authors: Pajovic Scepanovic Radmila , Vuletic Dusko , Christofi Stefania , Kallithraka Stamatina
Published: July 2024

The present study focuses on the effect of increasing maceration times (0, 2, 4, 6, and 10 days) on the extraction of phenolic compounds into two Montenegrin wines made with the autochthonous varieties Vranac and Kratošija. Significant differences were found in the total acidity, pH and alcohol content of these two varietal wines, which showed different responses to the maceration time. The total content of phenolic compounds (phenols, tannins and anthocyanins) increased significantly with longer maceration time, which is consistent with the existing literature. Specifically, the longest maceration time (10 days) consistently resulted in the highest levels of all parameters analysed. In addition, the anthocyanin profile determined by HPLC showed the interaction between maceration time and variety on the concentrations of the individual anthocyanins. Compared to Kratošija, Vranac wines consistently showed higher anthocyanin contents. In addition, the structural analysis of the tannins revealed that the mean degree of polymerisation (mDP), the percentage of prodelphinidins (%PD) and the percentage of galloylation (%Gall) changed with increasing maceration time. Significant correlations were found between the antioxidant activity values and the analytical parameters, including the structural characteristics of the tannins. This study provides important information on the interaction between maceration time and various varietal characteristics that influence the phenolic composition of Montenegrin wines and contributes to a deeper understanding of winemaking practices and wine quality.
From the Borderland, through Galicia, to the Upper Silesia. Memoirs about Janina Giżycka
Authors: Lusek Joanna
Published: July 2024

Janina Giżycka urodziła się 16 maja 1877 r. w pobliżu Kamieńca Podolskiego. Uzyskała patriotyczne wychowanie. W 1895, zmuszeni do opuszczenia zaboru rosyjskiego, Giżyccy udali się do Krakowa, gdzie Janina podjęła studia na Wyższych Kursach dla Kobiet Baranieckiego i zaangażowała się w działalność Towarzystwa Szkoły Ludowej. W 1900 r. kontynuowała naukę u Urszulanek w Beaugency, potem na Sorbonie i w College de France w Paryżu, a także na kursach pielęgniarstwa w Krakowie, Berlinie i Paryżu. Podczas I wojny światowej pracowała jako siostra Czerwonego Krzyża w szpitalach wojskowych. Prowadziła kursy pielęgniarskie dla dziewcząt. Zaangażowała się w działalność Towarzystwa Opieki nad Legionistami. Po wojnie zamieszkała w Bytomiu na Górnym Śląsku i włączyła się w prace Polskiego Komisariatu Plebiscytowego i Delegatury Polskiego Czerwonego Krzyża w Bytomiu. Podczas Trzeciego Powstania Śląskiego pracowała jako naczelna pielęgniarka w punktach żywieniowych w Szopienicach i Łabędach. Po podziale Górnego Śląska, jako delegatka Towarzystwa Szkół Ludowych odwiedzała obozy uchodźców i powstańców śląskich. W 1922 r. uczestniczyła w uroczystości zorganizowanej dla uczczenia powrotu Górnego Śląska do Macierzy w Królewskiej Hucie, gdzie zamieszkała i pracowała jako nauczycielka francuskiego w Miejskiej Wyższej Szkole dla Kobiet. Później prowadziła czytelnię miejską i redagowała niedzielny dodatek prasowy dla kobiet. Zmarła 24 sierpnia 1937 r. została pochowana w grobie rodzinnym na cmentarzu Rakowickim w Krakowie.