bluuebunny/crossref_metadata_2025 huggingface dataset:
Sea wave modeling with X-band COSMO-SkyMed© SAR-derived wind field forcing and applications in coastal vulnerability assessment
Authors: Benassai G. , Montuori A. , Migliaccio M. , Nunziata F.
Published: March 2013

Abstract. In this paper, X-band COSMO-SkyMed© synthetic aperture radar (SAR) wind field data are first used to force coastal wind wave modeling for both sea wave numerical simulation and coastal vulnerability assessment purposes. The SAR-based wind field retrieval is accomplished by resolving the SAR-based wind speed and wind direction retrieval problems independently. The sea surface wind speed is retrieved through the azimuth cut-off procedure, and the sea surface wind direction is determined by the multi-resolution analysis of the discrete wavelet transform. The wind wave modeling is based on the third-generation Simulating WAves Nearshore (SWAN) model, which is used for sea wave state estimation in coastal and inland regions. The coastal vulnerability assessment is provided by means of a key parameter, known as impact index, which evaluates the coastal risk due to the inundation of the inshore land. Experiments consist of SWAN numerical simulations run with respect to some relevant wave storms recorded in the southern Tyrrhenian Sea on 2010, with applications in coastal vulnerability assessment along the Sele coastal plain. Experimental results show the benefits of blended wind field products, provided by European Centre for Medium Weather Forecast (ECMWF) model winds and SAR-based wind field estimations, for both wind wave modeling and coastal vulnerability assessment purposes.
Influence of winds on temporally varying short and long period gravity waves in the near shore regions of the eastern Arabian Sea
Authors: Glejin J. , Sanil Kumar V. , Balakrishnan Nair T. M. , Singh J.
Published: March 2013

Abstract. Wave data collected off Ratnagiri, west coast of India, during 1 May 2010 to 30 April 2012 are used in this study. Seasonal and annual variations in wave data controlled by the local wind system such as sea breeze and land breeze, and remote wind generated long period waves are also studied. The role of sea breeze on the sea state during pre- and postmonsoon seasons is studied and it is found that the maximum wave height is observed at 15:00 UTC during the premonsoon season, with an estimated difference in time lag of 1–2 h in maximum wave height between premonsoon and postmonsoon seasons. Observed waves are classified in to (i) short waves (Tp < 8 s), (ii) intermediate waves (8 < Tp < 13 s), and (iii) long waves (Tp> 13 s) based on peak period (Tp) and the percentages of occurrence of each category are estimated. Long period waves are observed mainly during the pre- and the postmonsoon seasons. During the southwest monsoon period, the waves with period > 13 s are a minimum. An event during 2011 is identified as swells propagated from the Southern Ocean with an estimated travelling time of 5–6 days. The swells reaching the Arabian Sea from the south Indian Ocean and Southern Ocean, due to storms during the pre- and postmonsoon periods, modify the near surface winds due to higher phase wave celerity than the wind speed. Estimation of inverse wave age using large-scale winds such as NCEP (National Centers for Environmental Prediction) reflects the presence of cyclonic activity during pre- and postmonsoon seasons but not the effect of the local sea breeze/land breeze wind system.
Disruption of circadian rhythm increases the risk of cancer, metabolic syndrome and cardiovascular disease
Authors: Shanmugam Vignesh , Wafi Amro , Al-Taweel Nawaf , Büsselberg Dietrich
Published: March 2013

Incidents of non-communicable diseases (NCD) like cardiovascular diseases, cancer, diabetes,
and chronic respiratory disease have increased dramatically and are currently the leading causes
of death worldwide. Their rising incidents coincide with the dramatic changes in industrialization
and development of societies over the past few hundred years. Therefore, current lifestyle
practices should be further explored to uncover novel risk factors for certain cancers (i.e. colon,
prostate, and breast cancer), metabolic syndrome (i.e. diabetes and obesity), and cardiovascular
disease (i.e. coronary artery disease). This review discusses how a disruption of the “biological
clock” or circadian rhythms could be involved in the development of these diseases as circadian
rhythms control multiple physiological processes such as wake/sleep cycles, hormonal levels,
body temperature, metabolism, and immune system.

Several environmental factors that disrupt circadian rhythms can be identified including
exposure to artificial light and electromagnetic (EM) waves, unbalanced diet and night shift work.
The mechanisms of how these “chronodisruptors” are associated with NCDs will be discussed.
Furthermore, the involvement of genetic factors in the disturbance of circadian rhythms and
predisposition to NCDs will be highlighted.

Overall there is strong evidence from animal models and epidemiological studies underlining
that circadian disruption is a significant player in several diseases particularly the multifactorial
diseases that pose a significant public health challenge in contemporary society. A circadian
disruption-based model of cancer, metabolic syndrome and cardiovascular disease etiology can
be proposed. But, to fully understand the complex interactions of the different components in the
network of disease development due to disruption of circadian rhythms, more investigations are
needed to unravel the causal relationship between modern lifestyle, circadian rhythm disruption
and complex disease. This summary will help to better understand the mechanisms and aid the
development of new methods and policies to lower incidence/death rates.
MINI-CURSO “BIOLOGIA FORENSE: A CIÊNCIA DESVENDANDO O CRIME” - DISCUTINDO TECNOLOGIA E CIÊNCIA EM SALA DE AULA
Authors: Berriel Yngrid Garay , Babá Adriane Yumi , Ossucci Gabrielle , Gianotto Dulcinéia Ester Pagani
Published: March 2013

Forensic Biology is applied to criminal investigations every day. Because of its appeal to human curiosity, it has been largely explored by TV series. Aiming to supply the students with an up-to-date subject, uncommonly discussed in Biology classes, an opportunity has emerged of presenting a short course on Forensic Biology to 2ndand 3rdgrade students of a High School in Maringá, Brazil. In order to get the students to understand the importance of training experts in this area of knowledge and how the latter behave on a crime scene, various didactics activities have been performed including practices and teamwork, rising of hypothesis and discussions which, according to those attending, were essential on developing the knowledge acquired during the course. The debate on the technologies used by the Forensic Sciences have turn up efficient when building knowledge related to Biology and other areas which have been approached in the course
A NECESSÁRIA VINCULAÇÃO DO DESENVOLVIMENTO ECONÔMICO AOS DIREITOS FUNDAMENTAIS POR CONTA DAS CARTAS DA ONU E SEUS REFLEXOS NA CONSTITUIÇÃO BRASILEIRA DE 1988
Authors: Longo Caricielli Maisa , Longo Marcelo Pereira
Published: March 2013

This article seeks to associate economic development and rights, based on the 1988 Brazilian Constitution and UN Charter, which related to the matter in view of the concern for the welfare and human dignity.
MATERIAIS AUDIOVISUAIS DIDÁTICOS E EDUCAÇÃO SEXUAL NA ESCOLA: UMA PESQUISA NOS ACERVOS VIDEOGRÁFICOS DO MINISTÉRIO DA EDUCAÇÃO E CULTURA E MINISTÉRIO DA SAÚDE DO GOVERNO BRASILEIRO
Authors: Prado Vagner Matias do , Ribeiro Arilda Inês Miranda , Fazano Luciana Cristine
Published: March 2013

This article discusses sex differences as a research issue. It starts from the assumption that the work on sex education in schools should be effected beyond the biological dimension, focusing on the historical, cultural, social and political aspects that underlie the issue and influence the construction of cultural identities. In this manner, teaching support materials to implement these interventions are very important for the educational work, among them, the audiovisual materials are very productive. The proposed goal was to conduct a survey of educational videos with the Departments of Education, Culture and Health of the Brazilian Government in order to make a list containing titles of materials that could subsidize the pedagogical action. The measured results show a timid government initiative for the production of these materials, even sexuality shaping up as a crosscutting theme to be included as a school subject.
HODNOCENÍ RIZIK DOPADU PROJEKTŮ TĚŽBY UHLÍ NA RELIÉF MORAVSKO-SLEZSKÝCH KARPAT V ČESKÉ REPUBLICE: PŘÍPADOVÁ INŽENÝRSKO-GEOMORFOLOGICKÁ STUDIE DOBÝVACÍHO PROSTORU TROJANOVICE
Authors: Demek Jaromír , Mackovčin Peter , Slavík Petr
Published: March 2013

The aim of the paper is prediction and estimation of risks of planned hard coal deep mining in Trojanovice mining area below sensitive young terrain of the Moravian-Silesian Carpathians and impact of mining activities on the relief. The authors carried out detailed geomorphological mapping of the area, compiled digital geomorphological map and 3-D model of geomorphological hazards. The engineering-geomorphological analysis has shown that planned underground mining activities will accelerate geodynamic processes in the area and cause substantial changes of mountain and highland relief.
METODIKA SESTAVENÍ MAPY MOCNOSTÍ SEDIMENTŮ AUTOCHTONNÍHO KARPATU NA ÚZEMÍ ČESKÉ ČÁSTI HORNOSLEZSKÉ PÁNVE A BLÍZKÉHO OKOLÍ A NĚKTERÉ JEJÍ PROBLÉMY
Authors: Wlosok Jiří , Jirásek Jakub , Sivek Martin
Published: March 2013

Sedimentary formations of Karpathian represent the oldest widespread unit of the autochtonous Tertiary in the Czech part of the Upper Silesian Basin. Occurrence and distribution of thickness of the Karpatian point to complicated geological development. It was probably formed in tectonically predisposed sedimentary depressions with large infl uence of the Old Styrian nappes, which were thrusted over the area of original sedimentary cover in the north-eastern part of the Carpathian Foredeep. Main topic of our work is evaluation of possible mistakes in interpretation of the autochtonous Karpatian thickness. Original contour line maps of the autochtonous Karpatian distribution and thickness in the area of interest are based on exploratory borehole profiles.
Selecting the Right Metering Pump
Authors: McDowell Bill
Published: March 2013

A search for technology to increase system accuracy, reduce maintenance costs, and enhance an advanced supervisory control and data acquisition (SCADA) system led a Rancho Cucamonga, California, utility to replace its diaphragm‐type pumps and gas‐chlorine injection system with peristaltic pumps.
La reconversion des friches industrielles en quartiers durables
Authors: Benali Kenza
Published: March 2013

Dans le contexte actuel de développement urbain durable, la densification du tissu bâti existant s’est imposée comme une solution adéquate pour contrecarrer l’étalement urbain et ses effets néfastes. Les friches industrielles, vastes et souvent bien situées au coeur des villes, constituent à cet égard un potentiel de développement majeur. Ces espaces sous-utilisés sont depuis peu la cible privilégiée pour la réalisation d’écoquartiers ou de « quartiers durables ». D’abord développés dans les pays d’Europe du Nord, ces quartiers modèles ont par la suite connu une diffusion européenne et nord-américaine. Si, de manière générale, ils ont reçu un accueil favorable et ont connu une popularité grandissante en raison de leurs promesses et de leur urbanisme « vertueux », il reste que de grandes lignes critiques apparaissent dans la littérature spécialisée. Cet article vise d’abord à définir, à travers une revue de la littérature récente, ce mouvement actuel en aménagement, puis à évoquer les principales critiques qui lui sont adressées.
Mesurer l’accessibilité territoriale par les transports collectifs
Authors: Richer Cyprien , Palmier Patrick
Published: March 2013

L’accessibilité n’est pas un concept univoque. Si toutes les approches insistent sur l’enjeu du « potentiel de mobilité » pour l’espace et les sociétés, il convient de distinguer les multiples dimensions du système d’accessibilité territoriale (approche théorique). Cet article porte sur une de ses facettes, celle de l’accessibilité structurelle du territoire en transport collectif à travers la construction d’un indicateur multicritère (croisement de critères de temps, d’intensité des relations et de pénibilité des déplacements). L’enjeu est d’estimer plus finement des potentiels d’accessibilité en transport collectif (approche méthodologique) et d’interpréter (approche opérationnelle) les (dés)équilibres d’accès aux pôles d’excellence dans le territoire métropolitain lillois. Les résultats fournis par l’outil de calcul de l’accessibilité multimodale MUSLIW, développé au CETE Nord-Picardie, permettent de mettre en débat les politiques stratégiques de la Communauté urbaine de Lille Métropole (LMCU) dans une optique d’aide à la décision. La démarche élaborée dans cet article est mise en perspective avec la méthode anglo-saxonnePublic Transport Accessibility Level(PTAL) utilisée dans la planification stratégique au Royaume-Uni. Ce croisement des regards donne la mesure de l’enjeu d’une meilleure estimation de la performance territoriale des réseaux de transport collectif pour assister les autorités responsables de l’aménagement, par exemple, dans leur choix d’urbanisation et de normes de stationnement.
Преваленца некаријесних цервикалних лезија на територији општине Фоча
Authors: Жужа Александра , Крунић Јелена , Цицмил Смиљка , Стојановић Никола , Божовић Ђорђе
Published: March 2013

Uvod. Nekarijesne cervikalne lezije su gubitak tvrdog zubnog tkiva na vratuzuba, najčešće lokalizovan na vestibularnoj površini. Ovakav gubitak mineralizovanezubne strukture može biti uzrokovan različitim etiološkim faktorima,a može dovesti do neugodne preosjetljivosti, bolnih senzacija, patološkihpromjena u pulpi i konačno gubitka zuba. Cilj ove studije je bio da se odrediprevalenca nekarijesnih cervikalnih lezija kod stanovništva grada Foča.Metode. U studiju je metodom slučajnog izbora uključeno 138 stanovnikagrada Foča starosne dobi od 35-44 godine. Kliničkim pregledom posmatranesu cervikalne trećine vestibularnih površina zuba. Dubina detektovanihnekarijesnih lezija mjerena je parodontalnom sondom, a izmjerene vrijednostizatim transformisane u indeks zubnog trošenja.Rezultati. Premolari su zubi sa najčešćim nekarijesnim cervikalnim lezijama.Vrijednost indeksa zubnog trošenja 1 najčešće je zabilježena na donjimsjekutićima (12,3% donji lijevi lateralni sjekutić i 11,6% donji desni centralnisjekutić). Najveća učestalost indeksa 2 pronađena je na donjim prvim premolarima(18,1% donji lijevi prvi premolar; 15,9% donji desni prvi premolar),kao i vrijednost indeksa 3 (16,7% donji desni prvi premolar; 15,2% donji lijeviprvi premolar; 13,8% donji desni drugi premolar i 11,6% donji lijevi drugipremolar). Najveća vrijednost indeksa zubnog trošenja 4 pronađena je nadonjim desnim centralnim sjekutićima (3,6%). U pogledu ukupne učestalostisvih nivoa indeksa od 1- 4, najčešće zahvaćeni zubi bili su donji premolari.Zaključak. Zbog poboljšane prevencije karijesa susrećemo se sa povećanomfrekvencom nekarijesnog gubitka tvrdog zubnog tkiva. Zubi sa najvišenekarijesnih cervikalnih lezija u ovoj studiji su donji premolari, koji su imalii najveći procenat nivoa 2 i 3 indeksa zubnog trošenja.
Uspješno zatvaranje oroantralne komunikacije modifikovanom operacijom Caldwell - Lüc
Authors: Kujundžić Bojan , Golijanin Ranko , Marić Helena , Davidović Lado
Published: March 2013

Uvod. Stvaranje oroantralne komunikacije može da se desi prilikom vađenjabilo kog bočnog zuba gornje vilice, mada u preko 50% slučajeva nastajeposlije vađenja gornjih prvih molara. Cilj rada je da se pokaže kako se osammjeseci nakon vađenja zuba i uspostavljanja oroantralne komunikacije možeuspješno hirurški odstraniti patološki promijenjena sluzokoža maksilarnogsinusa i zatvoriti oroantralna komunikacija, koristeći modifikovanu metoduoperacije po Caldwell–Lüc-u.Prikaz bolesnika. U radu je prikazan bolesnik, muškarac star 36 godina, kojise javio u prijemnu ambulantu klinike za Oralnu hirurgiju Medicinskogfakulteta u Foči. Iz anamneze se saznaje da je razlog njegovog javljanja curenjenepoznatog i neprijatnog sadržaja u predjelu gornjeg lijevog kvadrantaalveolarnog nastavka maksile. Poslije urađenog rendgenskog snimka i oralnogpregleda postavljena je dijagnoza oroantralne komunikacije u predjeluizvađenog zuba 26 uz postojanje fistuloznog otvora. Pristupilo se sprovođenjukombinovane medikamentozno-hirurške terapije. Medikamentozna terapijapodrazumijevala je intramuskularnu primjenu antibiotika, ispiranje sinusnešupljine fiziološkim rastvorom svaki dan tokom 7 dana uz primjenu antibiotikalokalno u šupljinu. Na kraju, u cilju zatvaranja oroantralne komunikacije,urađena je modifikovana operacija po Caldwell – Lüc-u.Zaključak: Prikazana operacija po Caldwell–Lüc-u je jedino pouzdano rješenjeblagovremeno neotkrivenih postekstrakcionih komplikacija kod kojih je došlodo otvaranja sinusne šupljine i uspostavljanja oroantralne komunikacije. Jedinoovaj način omogućava dobru vidljivost same sinusne šupljine i mogućnostuočavanja patološki promijenjene sluzokože sinusa, koja u svakom slučajumora da se ukloni.
A Matter of Decency? Persistent Tensions in the Regulation of Domestic Service
Authors: Abrantes Manuel
Published: March 2013

The role of law in regulating and mediating social inequality has been the subject of longstanding debates. While recent research on domestic service acknowledges the importance of regulation, the legal configuration of this activity sector is seldom assessed in a detailed or critical manner. This article builds on the claim that systematic observation should be dedicated to developments in the regulation of domestic service both in the local and international contexts.. The first part of the article focuses on the advancement of law regarding domestic service in Portugal. The Domestic Workers Convention adopted by the International Labor Organization in 2011 provides a context for examining persistent constraints on change toward social recognition and equity. Difference between domestic service workers and standard wage earners is analyzed in depth, and nine unsolved practicalities of domestic service regulation in Portugal are examined in light of the recent international convention. Gender and ethnicity are identified as lingering political foundations of this employment sector. The minimal participation of domestic workers and their representatives in regulatory processes raises serious concern. The historical lens is used to clarify current particularities in the regulation of the sector.
An Efficient and Recyclable Catalyst for N‐Alkylation of Amines and β‐Alkylation of Secondary Alcohols with Primary Alcohols: SBA‐15 Supported N‐Heterocyclic Carbene Iridium Complex
Authors: Wang Dong , Guo Xu‐Qing , Wang Chen‐Xi , Wang Ya‐Nong , Zhong Rui , Zhu Xiao‐Han , Cai Li‐Hua , Gao Zi‐Wei , Hou Xiu‐Feng
Published: March 2013

A mesoporous silica (SBA‐15)‐supported pyrimidine‐substituted N‐heterocyclic carbene iridium complex was prepared and used as a catalyst for both environmentally friendly N‐alkylation of amines and β‐alkylation of secondary alcohols with primary alcohols. The structure of the supported iridium catalyst was characterized by Fourier transform infrared (FT‐IR), 13C and 29Si solid‐state nuclear magnetic resonance (NMR), small‐angle X‐ray scattering (SAXS), transmission electron microscopy (TEM), iridium K‐edge X‐ray absorption near‐edge structure (XANES) and extended X‐ray absorption fine structure (EXAFS) spectroscopic analyses which demonstrated that the coordination environment of the iridium centre and the 3‐dimensional‐hexagonal pore structure of SBA‐15 were retained after the immobilization. The catalyst was found to be highly efficient for both kinds of reaction on a wide range of substrates under mild conditions. Moreover, the supported iridium catalyst was obviously superior to the unsupported one in the N‐alkylation of aniline and β‐alkylation of 1‐phenylethanol with benzyl alcohol as substrate, which indicated that not only the iridium complex moiety but also the support material contributed to the catalytic activity of the supported iridium catalyst in these reactions. The supported iridium catalyst can be easily recycled by simple washing without chemical treatment, and exhibited excellent recycling performance without notable decrease in catalytic efficiency even after twelve test cycles for N‐alkylation of aniline with benzyl alcohol, nine cycles for N‐alkylation of different amines with different alcohols, and eight cycles for β‐alkylation of 1‐phenylethanol with benzyl alcohol, respectively.
Tuning the Peri Effect for Enantioselectivity: Asymmetric Hydrogenation of Unfunctionalized Olefins with the BIPI Ligands
Authors: Busacca Carl A. , Qu Bo , Grět Nicole , Fandrick Keith R. , Saha Anjan K. , Marsini Maurice , Reeves Diana , Haddad Nizar , Eriksson Magnus , Wu Jiang‐Ping , Grinberg Nelu , Lee Heewon , Li Zhibin , Lu Bruce , Chen Dajun , Hong Yaping , Ma Shengli , Senanayake Chris H.
Published: March 2013

The modular nature of the BIPI ligands allows for systematic optimization of each ligand region. The development of ligands optimized for asymmetric hydrogenation of the challenging unfunctionalized olefin substrate class is described. The naphthyl peri position, C‐8, has been identified as a critical stereocontrol element in the design of these ligands. Highly enantioselective ligands suitable for hydrogenation of tri‐ and tetrasubstituted olefins are detailed.
Controlling Metallurgical Phase Separation Reactions of the Ge0.87Pb0.13Te Alloy for High Thermoelectric Performance
Authors: Gelbstein Yaniv , Davidow Joseph , Girard Steven N. , Chung Duck Young , Kanatzidis Mercouri
Published: March 2013

We demonstrate the potential of metallurgical controlling of the phase separation reaction, by means of spark plasma sintering consolidation and subsequently controlled heat treatments sequence, for enhancement the thermoelectric properties of the p‐type Ge0.87Pb0.13Te composition. Very high ZTs of up to ∼2, attributed to the nucleation of sub‐micron phase separation domains and to comparable sized twinning and dislocation networks features, were observed. Based on the experimentally measured transport properties, combined with the previously reported phase separated n‐type (Pb0.95Sn0.05Te)0.92(PbS)0.08 composition, a maximal efficiency value of ∼11.5% was theoretically calculated. These ZT and efficiency values are among the highest reported for single composition non‐segmented bulk material legs.
Management of sinonasal chondrosarcoma: a systematic review of 161 patients
Authors: Khan Mohemmed N. , Husain Qasim , Kanumuri Vivek V. , Boghani Zain , Patel Chirag R. , Liu James K. , Eloy Jean Anderson
Published: March 2013

Background

This study reviews the published literature related to management of sinonasal chondrosarcoma. Clinical presentation, demographics, radiographic diagnosis, treatment, and management outcomes of this uncommon disease are reported.

Methods

A systematic review of studies for sinonasal chondrosarcoma from 1950 to 2012 was conducted. A PubMed search for articles related to this condition, along with bibliographies of the selected articles was performed. Articles were examined for patient data that reported survivability. Demographic data, disease site, treatment strategies, follow‐up, outcome, and survival were analyzed.

Results

A total of 63 journal articles were included, comprising a total of 161 cases of sinonasal chondrosarcoma. The average follow‐up was 77.4 months (range, 1 to 325.2 months). Surgical resection was the most common treatment modality, used in 72.0% of cases. A combination of surgery and radiation therapy was the second most commonly used treatment modality, used in 21.7% of cases.

Conclusion

This review contains the largest pool of sinonasal chondrosarcoma patients to date and suggests aggressive surgical resection is the most common treatment modality for this condition. The use of adjuvant radiotherapy for prevention of local recurrence after subtotal or total resection has not been proven effective. However, the use of radiotherapy in addition to surgical resection has shown benefit in some studies in terms of survival.
Mucosal brush biopsy of the oral cavity to detect local, peanut‐specific immunoglobulin E
Authors: Reisacher William R. , Cohen Justin C.
Published: March 2013

Background

This study compares the ability of mucosal brush biopsy (MBB) from 2 separate locations in the oral cavity to detect peanut‐specific immunoglobulin E (IgE) in patients who report adverse oral cavity reactions when ingesting peanuts.

Methods

Twenty patients who reported a history of oral cavity itching or swelling when ingesting peanuts underwent either MBB of the dorsal tongue (n = 10) or the vestibule (n = 10). Serum testing for total and peanut‐specific IgE, using standard immunofluorescent assay, was obtained for all patients. Total and specific IgE for each location were compared. Additionally, the correlation between MBB and peanut‐specific IgE on serum was determined using Fisher's exact probability testing.

Results

Peanut‐specific IgE was detected in 3 of 10 (30%) MBB specimens from the dorsal tongue and in 10 of 10 (100%) MBB specimens from the vestibule. The mean peanut‐specific IgE on MBB (kU/L) in the dorsal tongue group was 0.03 vs 0.17 in the vestibule group (p = 0.0002). No significant association was noted for peanut‐specific IgE between MBB and serum testing (p = 1.0).

Conclusion

This study demonstrates for the first time that peanut‐specific IgE can be detected using MBB in the oral cavity of patients who are symptomatic when consuming peanuts. The vestibule was a superior location compared to the dorsal tongue for oral cavity MBB, correlating very well with self‐reported symptoms. Peanut‐specific IgE on MBB overall did not correlate well with serum testing for peanut‐specific IgE.
Fabrication of transition‐metal‐doped polypyrrole/multiwalled carbon nanotubes nanocomposites for supercapacitor applications
Authors: Dhibar Saptarshi , Sahoo Sumanta , Das C. K.
Published: March 2013

Copper chloride (CuCl2)‐doped polypyrrole (PPy)/multiwalled carbon nanotube (MWCNTs) nanocomposites were synthesized by an in
situ oxidative polymerization method with ammonium persulfate as the oxidant in HCl medium and investigated as electrode materials for supercapacitors. The interaction of metal cations (Cu2+ ions) with PPy was confirmed by Fourier transform infrared spectroscopic analysis. The morphology of the nanocomposites was characterized by field emission scanning electron microscopy and high‐resolution transmission electron microscopy. Electrochemical characterizations of the composites materials were carried out by a three‐electrode probe method, where platinum and a saturated standard calomel electrode were used as the counter and reference electrodes, respectively. A 1M KCl solution was used as the electrolyte for all of the electrochemical characterizations. The transition‐metal‐ion doping enhanced the electrochemical properties of the conducting polymer. Among all of the composites, the CuCl2‐doped PPy/MWCNTs showed the highest specific capacitance value of 312 F/g at a 10 mV/s scan rate. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Orientation of HDPE inclusions within solid‐state drawn rubber‐modified isotactic polypropylene: DSC insight
Authors: Sližová Marta , Raab Miroslav
Published: March 2013

Effect of drawing temperature on the melting behavior of oriented isotactic polypropylene (PP) modified with ethylene‐propylene‐diene monomer rubber with a small amount of high‐density polyethylene (HDPE) is explored in this study. Injection‐molded specimens both neat and 8 vol % modified PP were solid‐state drawn to natural drawing ratio and characterized by X‐ray diffraction, dynamic mechanical analysis (DMA), Charpy impact test and differential scanning calorimetry (DSC). A synergy of orientation and embedding rubber particles caused a significant increase of low‐temperature notched impact strength of oriented blends. It was shown, that the DSC method can be used successfully for the indirect but very sensitive characterization of orientation on a nanometre scale. At the drawing temperature of 120°C, the DSC data indicated an incomplete transition of the PP crystalline structure: This is reflected by splitting and shifting of the melting peak of PP. An increase of the melting temperature of the HDPE inclusions by 3.5°C reflects the high orientation. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Opposite Modulation of Cell Migration by Distinct Subregions of Urokinase Connecting Peptide
Authors: Franco Paola , Carotenuto Alfonso , Marcozzi Cristina , Votta Giuseppina , Sarno Ciro , Iaccarino Ingram , Brancaccio Diego , De Vincenzo Anna , Novellino Ettore , Grieco Paolo , Stoppelli Maria Patrizia
Published: March 2013

Functional analysis of isolated protein domains may uncover cryptic activities otherwise missed. The serine protease urokinase (uPA) has a clear‐cut motogen activity that is catalytically independent and resides in its amino‐terminal growth factor domain (GFD, residues 1‐49) and connecting peptide region (CP, residues 132–158). To functionally dissect the CP region, we analysed the biological activity of two synthetic peptides corresponding to the N‐terminal [uPA‐(135–143), residues 135–143] and C‐terminal [uPA‐(144–158), residues 144–158] CP subregions. Most of the chemotactic activity of connecting peptide‐derived peptide (CPp, [uPA‐(135–158)]) for embryonic kidney HEK293/uPAR‐25 cells is retained by uPA‐(144–158) at nanomolar concentrations. In contrast, uPA‐(135–143) inhibits basal, CPp ‐, vitronectin‐ and fibronectin‐induced cell migration. Radioreceptor binding assays on intact HEK293 cells revealed that uPA‐(135–143) and uPA‐(144–158) are both able to compete with [125I]‐CPp, albeit with different binding affinities. The consequences of phospho‐mimicking, S138E substitution, were studied using [138E]uPA‐(135–158) and [138E]uPA‐(135–143) peptides. Unlike CPp, [138E]uPA‐(135–158) and [138E]uPA‐(135–143) exhibit remarkable inhibitory properties. Finally, analysis of the conformational preferences of the peptides allowed to identify secondary structure elements exclusively characterising the stimulatory CPp and uPA‐(144–158) versus the inhibitory uPA‐(135–143), [138E]uPA‐(135–158) and [138E]uPA‐(135–143) peptides. In conclusion, these data shed light on the cryptic activities of uPA connecting peptide, revealing the occurrence of two adjacent regions, both competing for binding to cell surface but conveying opposite signalling on cell migration.
Magnetic Anisotropy of Cyanide‐Bridged Core and Core–Shell Coordination Nanoparticles Probed by X‐ray Magnetic Circular Dichroism
Authors: Prado Yoann , Arrio Marie‐Anne , Volatron Florence , Otero Edwige , Cartier dit Moulin Christophe , Sainctavit Philippe , Catala Laure , Mallah Talal
Published: March 2013

The local symmetry and local magnetic properties of 6 nm‐sized, bimetallic, cyanide‐bridged CsNiCr(CN)6 coordination nanoparticles 1 and 8 nm‐sized, trimetallic, CsNiCr(CN)6@CsCoCr(CN)6 core–shell nanoparticles 2 were studied by X‐ray absorption spectroscopy (XAS) and X‐ray magnetic circular dichroism (XMCD). The measurements were performed at the NiII, CoII, and CrIII L2,3 edges. This study revealed the presence of distorted NiII sites located on the particle surface of 1 that account for the uniaxial magnetic anisotropy observed by SQUID measurements. For the core–shell particles, a combination of the exchange anisotropy between the core and the shell and the pronounced anisotropy of the CoII ions is the origin of the large increase in coercive field from 120 to 890 Oe on going from 1 to 2. In addition, XMCD allows the relative orientation of the magnetic moments throughout the core–shell particles to be determined. While for the bimetallic particles of 1, alignment of the magnetic moments of CrIII ions with those of NiII ions leads to uniform magnetization, in the core–shell particles 2 the magnetic moments of the isotropic CrIII follow those of CoII ions in the shell and those of NiII ions in the core, and this leads to nonuniform magnetization in the whole nanoobject, mainly due to the large difference in local anisotropy between the CoII ions belonging to the surface and the NiII ions in the core.
A New Dual‐Signalling Electrochemical Sensing Strategy Based on Competitive Host–Guest Interaction of a β‐Cyclodextrin/Poly(N‐acetylaniline)/Graphene‐Modified Electrode: Sensitive Electrochemical Determination of Organic Pollutants
Authors: Zhu Gangbing , Wu Liang , Zhang Xia , Liu Wei , Zhang Xiaohua , Chen Jinhua
Published: March 2013

Based on the competitive host–guest interaction between a β‐cyclodextrin/poly(N‐acetylaniline)/electrogenerated‐graphene (β‐CD/PNAANI/EG) film and probe or target molecules, a new dual‐signalling electrochemical sensing method has been developed for the sensitive and selective determination of organic pollutants. As a model system, rhodamine B (RhB) and 1‐aminopyrene (1‐AP) were adopted as the probe and target molecules, respectively. Due to the host–guest interaction, RhB molecules can enter into the hydrophobic inner cavity of β‐CD, and the β‐CD/PNAANI/EG‐modified glassy carbon electrode displays a remarkable oxidation peak due to RhB. In the presence of 1‐AP, competitive association to β‐CD occurs and the RhB molecules are displaced by 1‐AP. This results in a decreased oxidation peak current of RhB and the appearance of an oxidation peak current for 1‐AP, and the changes of these signals correlate linearly with the concentration of 1‐AP. When the value ΔI1‐AP+∣ΔIRhB∣ (ΔI1‐AP and ΔIRhB are the change values of the oxidation peak currents of 1‐AP and RhB, respectively) is used as the response signal to quantitatively determine the concentration of 1‐AP, the detection limit is much lower than that given by using ΔI1‐AP or ΔIRhB as the response signal. This dual‐signalling sensor can provide more sensitive target recognition and will have important applications in the sensitive and selective electrochemical determination of electroactive organic pollutants.
Tricyclometalated Iridium Complexes as Highly Stable Photosensitizers for Light‐Induced Hydrogen Evolution
Authors: Yuan Yong‐Jun , Yu Zhen‐Tao , Gao Hong‐Lin , Zou Zhi‐Gang , Zheng Chao , Huang Wei
Published: March 2013

The development of an efficient and stable artificial photosensitizer for visible‐light‐driven hydrogen production is highly desirable. Herein, a new series of charge‐neutral, heteroleptic tricyclometalated iridium(III) complexes, [Ir(thpy)2(bt)] (1–4; thpy=2,2′‐thienylpyridine, bt=2‐phenylbenzothiazole and its derivatives), were systematically synthesized and their structural, photophysical, and electrochemical properties were established. Three solid‐state structures were studied by X‐ray crystallographic analysis. This design offers the unique opportunity to drive the metal‐to‐ligand charge‐transfer (MLCT) band to longer wavelengths for these iridium complexes. We describe new molecular platforms that are based on these neutral iridium complexes for the production of hydrogen through visible‐light‐induced photocatalysis over an extended period of time in the presence of [Co(bpy)3]2+ and triethanolamine (TEOA). The maximum amount of hydrogen was obtained under constant irradiation over 72 h and the system could regenerate its activity upon the addition of cobalt‐based catalysts when hydrogen evolution ceased. Our results demonstrated that the dissociation of the [Co(bpy)3]2+ catalyst contributed to the loss of catalytic activity and limited the long‐term catalytic performance of the systems. The properties of the neutral complexes are compared in detail to those of two known non‐neutral bpy‐type complexes, [Ir(thpy)2(dtb‐bpy)]+ (5) and [Ir(ppy)2(dtb‐bpy)]+ (6; ppy=2‐phenylpyridine, dtb‐bpy=4,4′‐di‐tert‐butyl‐2,2′‐dipyridyl). This work is expected to contribute toward the development of long‐lasting solar hydrogen‐production systems.
ChemInform Abstract: Hydrothermal Synthesis of Hierarchical LiFePO4 Microspheres for Lithium Ion Battery.
Authors: Wang Qi , Deng SiXu , Wang Hao , Xie Ming , Liu JingBing , Yan Hui
Published: March 2013

The title microspheres are hydrothermally synthesized from (NH4)2HPO4, LiOH, and FeSO4 in sucrose solution (autoclave, 180 °C, 0.5—16 h).
ChemInform Abstract: Synthesis, Structure, and Transport Properties of Type‐I Derived Clathrate Ge46‐xPxSe8‐y (x = 15.4(1); y = 0—2.65) with Diverse Host—Guest Bonding.
Authors: Shevelkov Andrei V. , et al. et al.
Published: March 2013

A first clathrate compound with Se guest atoms, [Ge46‐xPx]Se8‐y□y (x = 15.4; y = 0—2.65; □ = vacancy) is prepared from the elements (873 K, 72 h) and characterized by powder and single crystal XRD, SAED, TEM, and TB‐LMTO‐ASA electronic band structure computations.
ChemInform Abstract: {Ta12}/{Ta16} Cluster‐Containing Polytantalotungstates with Remarkable Photocatalytic H2 Evolution Activity.
Authors: Li Shujun , Liu Shumei , Liu Shuxia , Liu Yiwei , Tang Qun , Shi Zhan , Ouyang Shuxin , Ye Jinhua
Published: March 2013

Compounds (III) and (VII) are tris‐(peroxotantalum)‐substituted Dawson‐ and Keggin‐type derivatives, whereas (IV) and (VIII) are tetrameric oligomers containing an unprecedented {Ta12} and {Ta16} core, respectively.
ChemInform Abstract: Organocatalyzed Baylis—Hillman Reaction: An Enantioselective Approach.
Authors: Thorat Prashant B. , Goswami Santosh V. , Khade Bhimrao C. , Bhusare Sudhakar R.
Published: March 2013

A series of new organocatalysts is designed based on hydrogen bonding motifs and applied to the title reaction.
ChemInform Abstract: N‐Heterocyclic Carbene Complexes of Nickel as Efficient Catalysts for Hydrosilylation of Carbonyl Derivatives.
Authors: Postigo Lorena , Royo Beatriz
Published: March 2013

A new Ni‐NHC‐complex displays high activity and excellent tolerance to functional groups in the reduction of aldehydes (I) and ketones (III).
ChemInform Abstract: A Simple and Convenient Method for Direct α‐Chlorination of Ketones with Ammonium Chloride and Oxone®.
Authors: Zhou Zhong Shi , Li Li , He Xue Han
Published: March 2013

The reaction proceeds at room temperature and is applied to the various linear and cyclic ketones and oxocarboxylic ester.
ChemInform Abstract: A Highly Active Bifunctional Iridium Complex with an Alcohol/Alkoxide‐Tethered N‐Heterocyclic Carbene for Alkylation of Amines with Alcohols.
Authors: Bartoszewicz Agnieszka , Marcos Rocio , Sahoo Suman , Inge A. Ken , Zou Xiaodong , Martin‐Matute Belen
Published: March 2013

A series of novel iridium complexes possessing chelating [NHC‐alcohol] ligands is prepared.
ChemInform Abstract: Iron(III) Tosylate Catalyzed Acylation of Alcohols, Phenols, and Aldehydes.
Authors: Baldwin Neil J. , Nord Anna N. , O'Donnell Brendan D. , Mohan Ram S.
Published: March 2013

Primary, secondary and some tertiary alcohols [cf.
ChemInform Abstract: Copper‐Catalyzed Three‐Component Borylstannylation of Alkynes.
Authors: Takemoto Yuki , Yoshida Hiroto , Takaki Ken
Published: March 2013

The presented new borylstannylation of alkynes occurs in a regio‐ and stereoselective manner.
ChemInform Abstract: Potassium 4‐Iodylbenzenesulfonate: Preparation, Structure, and Application as a Reagent for Oxidative Iodination of Arenes.
Authors: Yusubov Mekhman S. , Yusubova Roza Y. , Nemykin Victor N. , Maskaev Andrey V. , Geraskina Margarita R. , Kirschning Andreas , Zhdankin Viktor V.
Published: March 2013

A thermally stable and water‐soluble hypervalent iodine oxidant for oxidative iodination of aromatic substrates is synthesized.
ChemInform Abstract: Room‐Temperature Base‐Free Copper‐Catalyzed Trifluoromethylation of Organotrifluoroborates to Trifluoromethylarenes.
Authors: Huang Yuanyuan , Fang Xin , Lin Xiaoxi , Li Huaifeng , He Weiming , Huang Kuo‐Wei , Yuan Yaofeng , Weng Zhiqiang
Published: March 2013

This reaction runs in the absence of any additional base or oxidant and tolerates a variety of functionalities.
ChemInform Abstract: Synthesis of Five‐ and Six‐Membered Benzocyclic Ketones Through Intramolecular Alkene Hydroacylation Catalyzed by Nickel(0)/N‐Heterocyclic Carbenes.
Authors: Hoshimoto Yoichi , Hayashi Yukari , Suzuki Haruka , Ohashi Masato , Ogoshi Sensuke
Published: March 2013

The convenient method allows the synthesis of indanone and tetralone derivatives.
ChemInform Abstract: α‐Aryl‐Substituted Allenamides in an Imino‐Nazarov Cyclization Cascade Catalyzed by Au(I).
Authors: Ma Zhi‐Xiong , He Shuzhong , Song Wangze , Hsung Richard P.
Published: March 2013

This is an efficient method with high regioselectivity.
ChemInform Abstract: Ruthenium‐Catalyzed Direct ortho‐Alkynylation of Arenes with Chelation Assistance.
Authors: Ano Yusuke , Tobisu Mamoru , Chatani Naoto
Published: March 2013

The process allows the synthesis of various o‐substituted bisarenes, which can serve as precursors of polycyclic systems as is demonstrated for the preparation of heteroarene (X).
ChemInform Abstract: Phosphane‐Mediated Domino Synthesis of Tetrasubstituted Furans from Simple Terminal Activated Olefins.
Authors: Wang Jianfang , Zhou Rong , He Zheng‐Rong , He Zhengjie
Published: March 2013

A general, mild, and convenient highly efficient synthesis of the title compounds is developed from readily available starting materials with flexible substitution patterns.
ChemInform Abstract: Ir(I)‐Catalyzed C—H Bond Alkylation of C2‐Position of Indole with Alkenes: Selective Synthesis of Linear or Branched 2‐Alkylindoles.
Authors: Pan Shiguang , Ryu Naoto , Shibata Takanori
Published: March 2013

The differences between the N‐acetyl group and the N‐benzoyl group are used to obtain either linear or branched alkylation products.
ChemInform Abstract: Novel One‐Pot Synthesis of 2‐Substituted 3‐Alkoxyisoindolin‐1‐imine Derivatives from 2‐Cyanobenzaldehyde, Amine, and Alcohol.
Authors: Shen Sida , Xu Xingyu , Lei Min , Hu Lihong
Published: March 2013

The additional, efficient method for the preparation of the isoindole skeleton tolerates a broad spectrum of functionalities.
ChemInform Abstract: Highly Diastereo‐ and Enantioselective Organocatalytic One‐Pot Sequential 1,4‐Addition/Dearomative‐Fluorination Transformation.
Authors: Li Feng , Sun Long , Teng Yuou , Yu Peng , Zhao John Cong‐Gui , Ma Jun‐An
Published: March 2013

This reaction yields products with adjacent tertiary and quarternary stereocenters in good yields with high diastereo‐ and enantioselectivities.
ChemInform Abstract: Efficient One‐Pot Synthesis of 1H‐Pyrazolo[1,5‐b]indazoles by a Domino Staudinger—Aza‐Wittig Cyclization.
Authors: Zhao Fen‐Fen , Yan Yan‐Mei , Zhang Rui , Ding Ming‐Wu
Published: March 2013

Treatment of azides (I) with triphenylphosphine results in an initial abnormal Staudinger reaction which is followed by intramolecular aza‐Wittig reaction to produce the relatively unknown, biologically important heterocyclic scaffold.
ChemInform Abstract: SBA‐15/TFE (SBA‐15/2,2,2‐Trifluoroethanol) as a Suitable and Effective Metal‐Free Catalyst for the Preparation of the Tri‐ and Tetra‐Substituted Imidazoles via One‐Pot Multicomponent Method.
Authors: Rostamnia Sadegh , Zabardasti Ali
Published: March 2013

The title compounds are obtained in the one‐pot multicomponent reaction between benzil, aromatic aldehydes, amines and/or ammonium acetate.
ChemInform Abstract: Simple and Efficient Protocol for the Synthesis of Novel Dihydro‐1H‐pyrano[2,3‐c]pyrazol‐6‐ones via a One‐Pot Four‐Component Reaction.
Authors: Azzam Sadeq Hamood Saleh , Pasha M. A.
Published: March 2013

Ba(OH)2 is an efficient catalyst in the fast process if aromatic aldehydes are involved.
ChemInform Abstract: Synthesis of Chromans and 4H‐Chromenes: Exploring the Oxidation of 2H‐Chromenes and Dihydro‐1‐benzoxepines by Hypervalent Iodine(III).
Authors: Ahmad Anees , Silva Luiz F. Jr.
Published: March 2013

The reaction of the heterocyclic substrates with Koser′s reagent HTIB in the presence of orthoesters or alcohols is studied.
ChemInform Abstract: A Highly Diastereoselective Series of Nicholas Cyclization Reactions of N‐Boc‐Protected Propargylamines.
Authors: Brawn Peter , Tyrrell Elizabeth , Carew Mark , Tesfa Kibur Hunie , Greenwood Iain
Published: March 2013

This method yields cis‐substituted chromane derivatives.
ChemInform Abstract: Iron‐Mediated Direct Arylation with Arylboronic Acids Through an Aryl Radical Transfer Pathway.
Authors: Wang Jian , Wang Shan , Wang Gao , Zhang Ji , Yu Xiao‐Qi
Published: March 2013

FeS is successfully employed as an efficient catalyst for the direct C‐arylation of quinones, pyridines and related N‐heterocycles.
ChemInform Abstract: FSG‐Hf(NPf2)4 Catalyzed, Environmentally Benign Synthesis of 1,8‐Dioxodecahydroaridines in Water‐Ethanol
Authors: Hong Mei , Xiao Guomin
Published: March 2013

via three‐component one‐pot condensation of various aromatic aldehydes, 5,5‐dimethyl‐1,3‐cyclohexanedione and different aromatic amines or ammonium acetate
ChemInform Abstract: Pd‐Catalyzed C‐3 Functionalization of Indolizines via C—H Bond Cleavage.
Authors: Zhao Baoli
Published: March 2013

Direct C‐3 arylation or alkynylation of indolizines is achieved using Pd‐catalysis in the presence of silver salts.
ChemInform Abstract: Design and Synthesis of Coumarinyl 1,4‐Benzodioxanes as Potential Antioxidants.
Authors: Das Asish R. , Pal Gargi , Bhattacharyya Pranabes , Ghosh Arnab K. , Mukherjee Debasri , Bandyopadhyay Debasish
Published: March 2013

Preliminary investigations reveal that some products exhibit a significant in vitro free hydroxyl radical scavenging activity.
ChemInform Abstract: Synthesis of Dialkyl and Diaryl Benzylphosphonates Through a ZnI2‐Mediated Reaction.
Authors: Richardson Rebekah M. , Barney Rocky J. , Wiemer David F.
Published: March 2013

The spectrum of phosphite substrates used also includes hindered and optically active ones.
ChemInform Abstract: Significantly Fast Synthesis of S‐Glycosyl N‐Substituted Dithiocarbamate and S‐Glycosyl S′‐Substituted Trithiocarbonate Derivatives under Solvent‐Free Conditions.
Authors: Jana Manas , Misra Anup Kumar
Published: March 2013

Carbohydrates (I), (V) and (VIII) are used for the preparation of both types of title compounds, which are suitable for oligosaccharide synthesis.
ChemInform Abstract: Unravelling the Properties of Supported Copper Oxide: Can the Particle Size Induce Acidic Behavior?
Authors: Zaccheria Federica , Scotti Nicola , Marelli Marcello , Psaro Rinaldo , Ravasio Nicoletta
Published: March 2013

Review: 96 refs.
ChemInform Abstract: Synthesis of Substituted 2,6‐Dicyanoanilines and Related Compounds.
Authors: Borate Hanumant B. , Kudale Ananada S. , Agalave Sandip G.
Published: March 2013

Review: 266 refs.
ChemInform Abstract: Methane: A New Frontier in Organometallic Chemistry
Authors: Cavaliere Vincent N. , Mindiola Daniel J.
Published: March 2013

Review: 148 refs.
ChemInform Abstract: Asymmetric Henry Reaction Catalyzed by Transition Metal Complexes: A Short Review
Authors: Ananthi Nallamuthu , Velmathi Sivan
Published: March 2013

Review: 68 refs.
ChemInform Abstract: Advances in the Use of Enantiopure β‐Lactams for the Synthesis of Biologically Active Compounds of Medicinal Interests
Authors: Ojima Iwao , Zuniga Edison S. , Seitz Joshua D.
Published: March 2013

Review: 163 refs.
ChemInform Abstract: Benzotriazole as a Synthetic Auxiliary
Authors: Zorc Branka , Dzolic Zrinka Rajic , Butula Ivan
Published: March 2013

Review: 60 refs.
ChemInform Abstract: External Regulation of Controlled Polymerizations
Authors: Leibfarth Frank A. , Mattson Kaila M. , Fors Brett P. , Collins Hazel A. , Hawker Craig J.
Published: March 2013

Review: 78 refs.
ChemInform Abstract: Asymmetric Catalysis with Bis(hydroxyphenyl)diamides/Rare‐Earth Metal Complexes
Authors: Kumagai Naoya , Shibasaki Masakatsu
Published: March 2013

Review: ca. 200 refs.
ChemInform Abstract: Synthesis of Oligonucleotide‐Peptide Conjugates for Biomedical and Technological Applications
Authors: Avino Anna , Grijalvo Santiago , Perez‐Rentero Sonia , Garibotti Alejandra , Terrazas Montserrat , Eritja Ramon
Published: March 2013

Review: 19 refs.