bluuebunny/crossref_metadata_2025 huggingface dataset:
Oral administration of crocin-loaded solid lipid nanoparticles inhibits neuroinflammation in a rat model of epileptic seizures by activating SIRT1 expression
Authors: Kakebaraei Seyran , Gholami Mohammadreza , Nasta Touraj Zamir , Arkan Elham , Bahrehmand Fariborz , Fakhri Sajad , Jalili Cyrus
Published: August 2024

Background and purpose:

Epilepsy is a group of chronic neurological diseases caused by a complex set of neuronal hyper electrical activities and oxidative stress of neurons. Crocin is a natural bioactive agent of saffron with different pharmacological properties and low bioavailability. This study aimed to evaluate crocin-loaded solid lipid nanoparticles (SLNC) for neuroprotection activity and efficacy against pentylenetetrazol (PTZ)- induced epilepsy.

Experimental approach:

The rats were pretreated with SLNC and pure-crocin (PC; 25 and 50 mg/kg/day; P.O.) for 28 days before PTZ induction. Behavioral functions were evaluated by passive avoidance learning (PAL) tasks. Then, total antioxidant capacity (TAC), malondialdehyde (MDA), and pro-inflammatory factors were measured in the brain tissue using ELISA kits. Gene expression levels were analyzed with real-time polymerase chain reaction and immunohistochemical assay was used to assess the protein expression of sirtuin1 SIRT 1).

Findings/Results:

SLNC was prepared with an average particle size of 98.25 nm and 98.33% encapsulation efficiency. Memory deficit improved in rats treated with SLNC. Administering SLNC at 25 and 50 mg/kg significantly reduced MDA and proinflammatory cytokines while increasing TAC. Additionally, administering SLNC before treatment increased the levels of SIRT1, peroxisome proliferator-activated receptor coactivator 1α, cAMP-regulated enhancer binding protein, and brain-derived neurotrophic factor. Furthermore, SLNC administration resulted in the downregulation of caspase-3 and inflammation factor expression.

Conclusion and implications:

Overall, the obtained results showed that SLNC has better protective effects on oxidative stress in neurons, neurocognitive function, and anti-apoptotic and neuromodulatory activity than PC, suggesting that it is a promising therapeutic strategy for inhibiting seizures.
Cardiovascular Outcomes in COVID-19 Patients: A Retrospective Analysis of Intensive Care Unit Data from Saudi Arabia
Authors: Aleid Abdulsalam Mohammed , Ahmed Khadija Adel , Matar Hajar Ali , Hasan Ahmed , Alyami Najah Abdullah , Aljohani Ammar Mousa , Alkhamis Mohammad Abdulaziz , Albalawi Shorouq Daher M. , Alashjaee Ahmed Azam , Alsaegh Shouq Yousef , Alasmari Ahmed Mohammed , Samaren Moaied Mohammed , Bawahab Rinad Abdulwahab , Kharaba Ayman Mohammed , Alabdullah Hussain , Althubaiti Khalid Abdullah
Published: August 2024

Background:

The COVID-19 pandemic has brought to the fore significant challenges in understanding the disease’s impact on cardiovascular health. Emerging evidence suggests that COVID-19 patients, especially those with severe symptoms, face considerable cardiovascular complications.

Objectives:

This study aims to investigate the extent and nature of cardiovascular complications in COVID-19 patients admitted to intensive care units (ICUs) in Saudi Arabia, thereby contributing to the broader understanding of the disease’s cardiovascular impact.

Methods:

This study was conducted at Almoosa Hospital; this cohort study involved adult patients (aged 18 and above) hospitalized with confirmed COVID-19 and admitted to the ICU. Patients with preexisting cardiovascular conditions or incomplete medical records were excluded. The study focused on outcomes such as myocardial injury and arrhythmias, utilizing SPSS version 26 for logistic regression and survival analysis in data analysis.

Results:

Our research revealed a high incidence of myocardial injury and arrhythmias among severely ill COVID-19 patients. These findings highlight the significant cardiovascular impact of COVID-19, particularly in severe cases, extending beyond the common respiratory complications.

Conclusion:

The study underscores the critical need for vigilant cardiovascular care in managing severe COVID-19 cases. It suggests the potential need for revising medical protocols and emphasizes the importance of ongoing research, especially in understanding long-term cardiovascular outcomes in COVID-19 survivors. This research contributes valuable insights to the evolving landscape of COVID-19-related cardiovascular health implications.
Church and State relations in Lesotho: A historical review locating the voice of the church in Lesotho’s political and mainstream history
Authors: Leanya Dr. Rethabile Benedict
Published: August 2024

The year 2024 sees Lesotho celebrate 200 years since the formation of Basotho as a nation. In these 200 years, the church has played a significant role in nation building and development. This article explores and seeks to locate the voice and presence of the church both as an ecumenical body and as a prophetic voice within the tumultuous history of Lesotho’s politics with a specific timeframe from 1833-2002. A literature review of relevant academic articles as well as historical works is used to ensure that the accounts recorded are factually correct. The formation of Basotho in the 18th century is a direct result of violence and war in the form of Lifaqane. King Moshoeshoe I, founder of the Basotho nation believed that peace could be procured via the presence of missionaries, therefore denoting the establishment of the church as an important factor. Within Lesotho’s mainstream history, the role played by the church has often been referred to in passing. Common sayings like “Baruti ba Moshoeshoe (Moshoeshoe’s pastors/ministers), and Lesotho ke naha ea Bokresete (Lesotho is a Christian nation)” are often quoted, and yet the actual role that the church has played and continues to play in Lesotho’s history and development has been an after-thought. In light of this, this article locates the role that the church has played in different eras of Lesotho’s history. From the establishment of the 1 st church (Protestant Church) in Morija, to the formation of ecumenical bodies such as The Heads of the Churches and Church Council of Lesotho to the current emerging coalition democracies under the constitutional monarchy.
Apropriações da Geodiversidade no município de Rosário, Estado do Maranhão-Brasil
Authors: Santos Igor de Luccas , Feitosa Antonio Cordeiro
Published: August 2024

O estudo dos componentes do meio físico possibilita a identificação dos elementos abióticos requisitados pelas atividades humanas, para além da compreensão do suporte dos ecossistemas, abrangendo a configuração ambiental no processo de ocupação do espaço e no panorama da economia e da cultura. Este estudo foi desenvolvido no município de Rosário, estado do Maranhão, visando compreender a dispersão espacial dos elementos da geodiversidade e a importância de sua apropriação para o município. A metodologia constou da análise da literatura sobre o tema, levantamento e elaboração de material cartográfico e realização de atividades de campo, constatando-se a importância de alguns elementos da geodiversidade para a economia e a cultura local, sobretudo pela exploração de argila para produção artesanal e industrial de cerâmica, e exploração de areias e rochas graníticas para a utilização na indústria da construção civil. As atividades de exploração mineral e de beneficiamento ceramista têm elevado potencial de degradação ambiental, com danos imediatos ao ambiente, embora sejam registros marcados pela subnotificação, reforçando a necessidade de sua investigação. Com esta abordagem, espera-se subsidiar futuras discussões acerca do uso socioambiental de elementos do meio físico e a geoconservação.
A Novel Approach to Construct Finite Automata Using Grid and Product Automata
Authors: Rupam Nag  , Dibyendu Barman  , Abul Hasnat
Published: August 2024

This research aims to utilize an organized grid-based strategy to make the development of complex Finite Automata easier. Product Automata are used to merge many automata into a single automaton to integrate various computing processes. Combining these methodologies provides novel methods of improving the scalability and efficiency of automata building, broadening the field of research for automata theory and its applications. The scalability of this developed automated system will benefit sectors such as automotive production and logistics. The results indicate considerable improvements in construction time, memory usage, scalability, and resilience compared to older approaches. The performance of the developed method, as measured by construction time, memory utilization, scalability, robustness, application range, and complexity, is 25% to 50% higher than that of traditional methodologies in the literature.
Hubungan Tingkat Pengetahuan Dengan Kepatuhan Minum Obat Pada Penderita Hipertensi Di Kalurahan Margorejo Tempel Sleman Yogyakarta
Authors: Zahra Rizki Jullanar , Setyani Fransisca Anjar Rina , Aryu Puspasari Scholastica Fina
Published: August 2024

Latar belakang: Hipertensi merupakan penyakit yang tidak dapat disembuhkan sehingga pasien hipertensi perlu menjalani pengobatan seumur hidup. Pengetahuan yang dimiliki oleh pasien dapat memberikan perubahan perilaku terutama dalam melakukan pengobatan yang dianjurkan. Kepatuhan minum obat merupakan salah satu cara dalam mengurangi risiko komplikasi.
Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan tingkat pengetahuan dengan kepatuhan minum obat pada penderita hipertensi di Kalurahan Margorejo Tempel Sleman Yogyakarta.
Metode: Penelitian ini menggunakan metode kuantitatif deskriptif korelatif. Jumlah sampel yang digunakan sejumlah 77 responden yang diambil dengan teknik proportionate stratified random sampling pada tanggal 08-18 Desember 2022. Instrumen yang digunakan adalah kuesioner tingkat pengetahuan tentang pengobatan hipertensi dan kuesioner MMAS-8.
Hasil: Data dianalisis dengan uji Chi Square p value adalah 0.001 (p value < 0.05) menunjukkan bahwa terdapat hubungan signifikan antara tingkat pengetahuan dengan kepatuhan minum obat pada penderita hipertensi di Kalurahan Margorejo, Tempel, Sleman, Yogyakarta.
Simpulan: Peneliti merekomendasikan agar penderita hipertensi meningkatkan informasi terkait pengobatan hipertensi terutama dalam komplikasi hipertensi serta kader diharapkan untuk meningkatkan dukungan keluarga penderita hipertensi.
Hubungan Pengetahuan Ibu Hamil Tentang Antenatal Care Dengan Kepatuhan Kunjungan Antenatal Care
Authors: Ardianto Nur Zahra Ikaputri , Mahayanti Agnes , Wulandari Riski
Published: August 2024

Latar Belakang: Pelayanan Antenatal Care diprogramkan oleh pemerintah guna mengatasi lonjakan Angka Kematian Ibu hamil, mempersiapkan kondisi ibu secara jasmani rohani, mempersiapkan masa bersalin hingga masa nifas. Pelayanan dilakukan sebanyak 6 kali kunjungan dimana 2 kali kunjungan akan langsung bertemu dengan dokter.
Tujuan: Mengetahui hubungan pengetahuan ibu hamil tentang ANC dengan kepatuhan kunjungan ANC.
Metode: Penelitian ini merupakan penelitian kuantitatif dengan pendekatan cross sectional. Populasi adalah seluruh ibu hamil yang melakukan pemeriksaan ANC berjumlah 668 orang. Penelitian ini diikuti 103 responden yang diambil dengan teknik accidental sampling. Instrumen menggunakan kuesioner pengetahuan ANC dan hasil catatan kunjungan pemeriksaan ANC. Analisis data menggunakan analisis univariat dan juga analisis bivariat dengan uji statistik Spearman Rank.
Hasil: Hasil penelitian didapatkan 63.1% ibu memiliki pengetahuan baik dan 36.9% memiliki pengetahuan cukup tentang ANC, 80.6% ibu patuh dan 19.4% ibu tidak patuh melakukan pemeriksaan ANC. Terdapat hubungan antara pengetahuan ibu hamil tentang ANC terhadap kepatuhan kunjungan ANC dengan nilai signifikasi p 0.000 (<0.05) dengan koefisien koralasi r -0.375.
Simpulan: Terdapat hubungan yang menunjukkan nilai signifikan lemah dan memiliki pola negatif antara pengetahuan ibu hamil tentang ANC terhadap kepatuhan kunjungan ANC. Tenaga kesehatan diharapkan dapat meningkatkan kegiatan promotif dengan menggunakan pilihan media yang menarik dan dengan bahasa yang mudah dipahami ibu dengan berbagai karakteristik.
Kata kunci: Antenatal Care, Pengetahuan, Kepatuhan Kunjungan
Analisis Faktor Berhubungan Dengan Tingkat Kecemasan Perawat Menghadapi Kegawatdaruratan di Unit Stroke Pasca Pandemi Covid-19
Authors: Ismoyowati Tri Wahyuni
Published: August 2024

Latar Belakang: Munculnya virus Covid-19 akhir tahun 2019 menimbulkan kecemasan di berbagai kalangan. Perawat merupakan garda terdepan dalam penanganan dan perawatan pasien selama 24 jam beresiko tinggi untuk terpapar. Studi pendahuluan di ruang Unit Stroke RS Swasta di  Yogyakarta, tehnik observasi dan wawancara kepada 10 orang perawat, 7 orang mengatakan sangat cemas menangani kegawatdaruratan dan 3 orang mengatakan biasa saja. Tujuan: Mengetahui faktor-faktor yang berhubungan dengan tingkat kecemasan perawat di unit stroke dalam menghadapi kegawatdaruratan dalam masa pandemi Covid-19. Metode: Desain penelitian kuantitatif korelasi, pendekatan cross sectional. Populasi seluruh perawat di unit stroke RS di Yogyakarta 2022. Total sampling (37 responden). Alat pengumpul data kuesioner kecemasan modifikasi HARS. Analisis data univariate dan bivariate. Hasil: Responden penelitian ini berusia 46-55 tahun, berpendidikan D3, dan memiliki masa kerja lama >10 tahun. Tingkat kecemasan perawat terbanyak tidak ada kecemasan (78,38%). Hubungan antara usia dengan tingkat kecemasan p-value: 0,271. Hubungan antara pendidikan dengan tingkat kecemasan p-value: 0,854. Hubungan antara masa kerja dengan tingkat kecemasan p-value: 0,609. Kesimpulan: Tidak ada hubungan antara usia, pendidikan dan masa kerja dengan tingkat kecemasan pada perawat di unit stroke dalam menghadapi kegawatdaruratan dalam masa pandemi Covid-19 di RS di Yogyakarta 2022. Saran: Peneliti selanjutnya diharapkan melakukan penelitian lebih lanjut tentang faktor-faktor lain yang dapat mempengaruhi tingkat kecemasan perawat.
Kata Kunci: Faktor- faktor, Kecemasan perawat, Covid-19, Kegawatdaruratan,  Unit Stroke
Kasus Kejahatan pada Anak Marak. Salah Siapa? (Analisis Penerapan Undang-Undang Perlindungan Anak)
Authors: Lihhiati Lihhiati
Published: August 2024

Violence against children is still prevalent in the society. At the end of 2022, there were 16,106 cases of violence. Itâ€™s higher than the previous year which had 14,517 cases. Violence against children become a harsh reality for all of us because there are many children still living in the conditions that are far from feeling safe and comfortable. The right of the child to receive life protection and the ability to grow and develop themselves is fully guaranteed by the state. Itâ€™s legitimized in the 1945 constitution of Indonesia and regulated in Law No. 35 of 2014. The author interested in conducting analysis on the implementation of the child protection policy by using qualitative descriptive method. This interest is driven by the number of cases of violence against children which occur every year and are neither prevented nor minimized by the law. The author uses a literature study approach and conducts content analysis on data collected from news, journals, law, and websites related to the topic of this issue. As a result, apart from identifying several individual drivers or motivations, there are several factors that should be considered by all parties, especially the government, in terms of communication activities amidst the complexity of people's lives in the digital era.
Eksplorasi Brand Image Virtual Hotel Operator di Mata Mitra : Studi Kualitatif Reddoorz Indonesia
Authors: Agung Ari Cahya Wibawa Anak
Published: August 2024

Penelitian ini bertujuan untuk bagaimana RedDoorz dapat mengeksplorasi brand image di mata mitra untuk membangun citra positif sebagai perusahaan VHO dengan menggunakan analisis metode kualitatif deskriptif. Obyek dari penelitian ini adalah RedDoorz Indonesia sebagai penyedia jasa akomodasi penginapan selaku pihak VHO (Virtual Hotel Operator) yang terus melakukan transformasi brand image secara digital. Penelitian menggunakan jenis pendekatan deskriptif kualitatif. Metode penelitian dengan meneliti kondisi sebuah objek yang alamiah sehingga peneliti sebagai instrumen kunci yang menyusun teknik pengumpulan data dengan observasi, wawancara, dan dokumentasi guna menjelaskan data-data yang bersifat kualitatif, analisis data induktif, dan hasil penelitian yang bersifat pemahaman makna, keunikan, mengkonstruksi sebuah fenomena, dan menciptakan hipotesis. Hasil wawancara menunjukkan bahwa mitra masih mempercayai RedDoorz sebagai bentuk brand trust untuk pengelolaan aset mereka. Studi dan analisis menunjukkan bahwa RedDoorz harus mengevaluasi dan melakukan eksplorasi brand image beralih ke brand characteristic yang lebih kuat dibandingkan yang sekarang dan masih perlu usaha yang maksimal untuk mempertahankan brand trust di mata mitra. Proses ini dilakukan secara bertahap dengan kehadiran VHO yang bukan tidak mungkin akan semakin bertumbuh setiap tahunnya, jika RedDoorz tidak berbenah dan mengelola brand image secara bijak akan sangat mungkin tertinggal. Data yang dikumpulkan berdasarkan wawancara mitra menunjukkan bahwa brand image RedDoorz saat ini dinilai cukup baik namun harusnya bisa lebih maksimal ditingkatkan dan dievaluasi secara berkala untuk menarik lebih banyak mitra untuk bergabung.
An Analysis of the Vocabulary Practice Program at Modern Islamic Boarding School
Authors: Zainudin Zainudin
Published: August 2024

This study aims to describe and analyze about vocabulary practice program. The results of this study are expected to be used to improve the existence of vocabulary practice program. This study takes the background at MA Nurussalam Modern Islamic Boarding School Sidogede Belitang OKU Timur. The research was designed in qualitative interpretive research design and used descriptive survey in the type of cross-sectional survey. The data collection was conducted by observation, interview and distributing questionnaires. The data has been collected from the result of this study was analyzed by describe using tabulated the data graphically in the tables and discussed the explanation of each respondentâ€™s answer through questionnaires and from that can be drawn the conclusion. The result of this study is shown: (1) this program played a role to improve the quality of speaking proved by increasing studentâ€™s competence of vocabulary and comprehension which hold in a week five times in 30 minutes after Shubuh prayer and school time and seemly made teaching and learning more attractive and be better (2) 84.9% of respondent agreed that student could improve their English ability by participation support agendas.
KONSEP DASAR ANALISIS KEBIJAKAN PENDIDIKAN
Authors: Supangi Hendra Mahardika
Published: August 2024

This journal explains how analysis in the world of education and how to implement it by the values ​​that lead to changes in the world of education. Educational policy analysis is a procedure using data to produce information as well as for the formulation of solving an educational problem, and also as an applied social science structured with the aim of the substance of educational policy to make it easier to identify problems in education. Therefore the government and certain parties improve and maintain policies that lead to the common good in education.
ANALISIS STRATEGI GURU DALAM MEMBENTUK KEDISIPLINAN PESERTA DIDIK DI SMKN 5 MAJENE
Authors: Rahmat Kurniawan  , Siti khumairah fikrillah
Published: August 2024

Tujuan dari penelitian ini adalah untuk: 1) mendeskripsikan strategi guru dalam membentuk kedisiplinan peserta didik  SMKN 5 Majene, 2) mendeskripsikan faktor pendukung dan penghambat starategi guru dalam membentuk kedisiplinan  SMKN 5 Majene. Penelitian ini merupakan penelitian kualitatif deskriptif, teknik pengumpulan data yang digunakan yaitu observasi, wawancara, dan dokumentasi yang dianalisis  dengan cara mengumpulkan data, menganalisis data, kemudian menarik kesimpulan. Hasil penelitian menunjukkan bahwa strategi guru dalam membentuk kedisiplinan peserta didik adalah membimbing dan mengarahkan perilaku peserta didik ke arah positif, memperlihatkan perilaku disiplin yang baik pada peserta didik, mengawasi seluruh perilaku peserta didik , mengendalikan seluruh perilaku peserta didik , dan memberikan hukuman atau ganjaran yang sifatnya membangun. Adapun faktor penghambat guru yaitu terdiri faktor internal (kurangya kesadaran diri peserta didik) dan faktor eksternal (keluarga, sekolah, dan masyarakat). Sedangkan faktor pendukung guru yaitu perlunya kerjasama antar sesama guru dan personil disekolah dan kerja sama antara guru dengan orang tua peserta didik.
EFEKTIVITAS STRATEGI MOVIE LEARNING UNTUK MENINGKATKAN HASIL BELAJAR PESERTA DIDIK PADA MATA PELAJARAN PENDIDIKAN AGAMA ISLAM KELAS IX A SMP NEGERI 2 PAMBOANG
Authors: Saddang Muhammad
Published: August 2024

Fokus penelitian ini adalah bagaimana penggunaan strategi pembelajaran film dapat meningkatkan hasil belajar peserta didik di kelas IX A SMPN 2 Pamboang. Tujuan penelitian ini adalah untuk mengetahui hasil belajar peserta didik sebelum dan setelah menggunakan strategi movie learning, dan mengetahui apakah strategi movie learning efektif untuk meningkatkan hasil belajar peserta didik. Penelitian eksperimen ini menggunakan desain One Grup Pre-Test and Post-Test design. Penelitian ini melibatkan 27 peserta didik kelas IX A SMPN 2 Pamboang. Instrument yang digunakan ialah tes, dan menggunakan analisis deskriptif dan inferensial. Hasil penelitian ini menunjukkan bahwa hasil belajar peserta didik sebelum menggunakan strategi movie learning termasuk dalam kategori rendah dengan nilai rata-rata 60,25. Sebaliknya, hasil belajar siswa setelah menggunakan strategi movie learning termasuk dalam kategori sedang dengan nilai rata-rata 78,20. Selanjutnya hasil uji paired sample t-test  menghasilkan nilai sig 0,000 sehingga sig (2-tailed) < α atau (0,000 < 0,05), maka H0 ditolak dan H1 diterima. Hal tersebut dapat disimpulkan bahwa strategi movie learning efektif untuk meningkatkan hasil belajar peserta didik pada mata pelajaran Pendidikan Agama Islam kelas IX A SMPN 2 Pamboang.
PERAN KEPALA SEKOLAH DALAM MENGIMPLEMENTASIKAN NILAI-NILAI PENDIDIKAN AGAMA ISLAM PADA PESERTA DIDIK DI SMA GUPPI SALAWATI KABUPATEN SORONG
Authors: S Sukman
Published: August 2024

This study aims to describe the role of the principal in implementing the values that contain Islamic education and to identify the supporting and inhibiting fastors experienced by the principal in implementing the values that contain Islamic education. This research is a qualitative research. This type of research is field research. Methods of data collection using observation techniques, interviews and documentation. Furthermore, the data is presented in an appropriate from so that it is read and understood, then the data is analyzed and conclusions are drawn.
The results of this study state tha: 1) the role of the principal in implementing values that contain Islamic religious education to GUPPI SAlawati high school students is maxzimized, it can be seen from the role of the principal which is very important for the progress of the school and fostering students about religion, namely a) implement Dhuha prayer, b) implement reading surah yasin, c) implement Zduhur player, d) implement lectures/cultum, e) implement recitation once a month. 2) supporting and inhibiting factors for the principal, including: a) supporting factors:i) there is support from 100% of teachers, ii) the environment around the school, b) inhibiting factors: i) parental factors, ii) heandpone factors, ii) community environmental factors.
PROBLEMATIKA GURU DALAM MENERAPKAN KURIKUUM MERDEKA BELAJAR DI SD ISLAM TERPADU TAHFIDZULQUR’AN LEMBANG
Authors: Aan Setiawan
Published: August 2024

Implementasi Kurikulum Merdeka Belajar di Sekolah Dasar memunculkan berbagai tantangan bagi guru dalam menyesuaikan jenis asesmen dengan tujuan pembelajaran, mengatasi keterbatasan pemahaman terkait kurikulum baru, dan memperoleh keterampilan dasar seperti penggunaan teknologi informasi. Penerapan Kurikulum Merdeka di SD Islam Terpadu Tahfidzul Qur'an menunjukkan adanya kesulitan dalam efektivitas guru dan pemahaman terhadap materi ajar. Langkah-langkah seperti pelatihan implementasi kurikulum, perencanaan yang baik, pengembangan model pembelajaran inovatif, serta penyesuaian dengan kompetensi dasar kurikulum menjadi kunci dalam mengatasi problematika tersebut. Observasi di SD tersebut menunjukkan bahwa penerapan Kurikulum Merdeka Belajar dilakukan secara bertahap, dengan kelas tertentu sudah mulai menerapkannya. Dengan kolaborasi antara pemerintah, guru, dan stakeholder pendidikan, diharapkan implementasi Kurikulum Merdeka dapat meningkatkan kualitas pendidikan dan mempersiapkan peserta didik menghadapi masa depan.
ANALISIS SISTEM INFORMASI GEOGRAFIS PARIWISATA DI KABUPATEN SEMARANG
Authors:   Universitas Kristen Satya Wacana, Wahyudi Irawan Parulian
Published: August 2024

As time goes by, technology is also developing, especially in the field of Geographic Information Systems (GIS). Geographic Information Systems (GIS) have become an important tool in analyzing, managing, and designing. In various fields and sectors. Semarang Regency is a region located in the province of Central Java which has many very diverse tourist destinations. Tourist destinations in Semarang Regency are relatively low in visitors compared to other regions. Therefore, the aim of this research is to design an application that functions to introduce tourist destinations in Semarang Regency to the wider community by adopting Geographic Information System (GIS) technology. This application makes it easier for visitors to find out tourist locations, see locations virtually using images, see place ratings based on public assessments, looking at the costs required to access tourist areas, etc. This design method uses qualitative methods and system design using UML (Unified Modeling Language).
ANALISIS USER EXPERIENCE PADA APLIKASI VOTING BERBASIS FLUTTER: STUDI EVALUASI MENGGUNAKAN UEQ+
Authors:   Universitas Harapan Bangsa, Sandi A Arif Setia
Published: August 2024

This study aims to analyze user experience (UX) on the Muhammadiyah Paguyangan Voting Application Based on Flutter (EVoMu) to support electronic voting in selecting new leadership in the Muhammadiyah Paguyangan organization. This evaluative study employs the User Experience Questionnaire Plus (UEQ+) method, covering four main dimensions: Efficiency, Intuitive Use, Visual Aesthetic, and Trust. The author gathered data from 120 users who participated as voters in this election process. The research yielded a positive response to the EVoMu application, as evidenced by the overall scale average score exceeding 0.8. Additionally, data diversity across all scales was noted to be at a very good and acceptable level. Measurement results indicate high reliability across all scales. The trust level in the application emerges as the most influential factor in its implementation, with a mean importance rating of 2.68.
Vacina contra a gonorreia: desafios e impasses no desenvolvimento e implementação
Authors: Mello Catharine Mattos , Vilar Lucas Figueiredo Gonçalves , Lima Mariane Dantas , Fontana Beatriz Maria , Lucena Romulo Gonçalves de Moura
Published: August 2024

A gonorreia, uma infecção sexualmente transmissível causada pela bactéria Neisseria gonorrhoeae, continua a ser uma das ISTs mais comuns e preocupantes, principalmente devido ao aumento da resistência antimicrobiana. No Brasil, a infecção afeta majoritariamente jovens adultos e homens que fazem sexo com homens, impondo uma carga significativa ao sistema de saúde. A criação de uma vacina eficaz é um desafio crítico, devido à alta variabilidade genética da bactéria e à crescente resistência aos antibióticos. A implementação de tal vacina poderia aliviar os custos associados ao tratamento e melhorar a saúde pública globalmente.
Kajian Kriminologi Hijau Terhadap Studi Kasus Hilirisasi Tambang Nikel
Authors: Alfredo Rynaldi  , Efrata Hamonangan Sinaga  , Jhonathan Roganda Sitorus
Published: August 2024

Kriminologi Hijau menyoroti kejahatan lingkungan dan dampaknya terhadap korban, baik manusia maupun non-manusia, serta ekosistem secara keseluruhan. Dalam konteks hilirisasi nikel di Indonesia, green criminology dapat dikaitkan melalui analisis terhadap dampak lingkungan yang dihasilkan oleh industri pengolahan nikel. Secara kuantitatif hasil survei membuktikan bahwa hilirasi tambang nikel memberikan efek buruk terhadap lingkungan, mengganggu Kesehatan masyarakat, meningkatkan konflik sosial, kehilangannya sumber daya alam dan mata pencaharian. Selain itu, pemerintah seringkali berada pada posisi memprioritaskan keuntungan ekonomi daripada perlindungan lingkungan. Perusahaan tambang besar seringkali memiliki pengaruh politik yang mampu mempengaruhi keputusan kebijakan, sehingga membuat pemerintah kurang kritis dan responsif terhadap pelanggaran yang dilakukan oleh korporasi. Hal tersebut membuat celah dalam hukum yang memungkinkan korporasi untuk dapat melanjutkan praktik yang merugikan lingkungan.
The influence of physiological and functional characteristics of the body of girls aged 17-18 years on playing sports
Authors: Tazabek Yerkebulan , Zhunusbekov Zhaxybek , Avsiyevich Vitaliy , Belegova Aliya , Yermenova Batilya
Published: August 2024

Achieving competitive results in women’s sports for athletes aged 17-18 requires structuring training processes around their physiological characteristics. This article analyzes recent scientific data on the impact of sexual dimorphism in girls aged 17-18 on sports participation and training. Relevant scientific works from the past five years were collected and analyzed. At this age, girls undergo the final stage of sexual maturation. The effectiveness of sports activities varies individually, influenced by the ovarian-menstrual cycle, hormonal background, and symptoms in each cycle phase. Physical activity declines during the menstrual, ovulatory, and premenstrual phases, while postmenstrual and postovulatory phases are more favorable for sports participation. Performance indicators depend on sexual dimorphism: female athletes show unique features in central nervous system activity, high psycho-emotional excitability, and earlier development of somatic and physical qualities compared to males. The skeletal structure in 17-18-year-old female athletes is smaller and shorter, with a wider pelvis and more developed shoulder girdle. These findings can be used by sports schools, rehabilitation specialists, coaches, and sports physicians to adapt and structure training processes, taking into account the physiological characteristics of 17-18-year-old female athletes, aiming for highly competitive results.
Keywords: Sexual Dimorphism, Hormonal Changes, Women’s Sports, Physical Culture, Sports Performance.
Effect of exercise rehabilitation on breath muscles in COPD patients
Authors: Hamad Shimal , Ahmed Hawkar , Khudair Hussain , Hadi Ammar , Salih Riyadh
Published: August 2024

This study aimed to determine the effect of exercise rehabilitation on the breathing muscles of Chronic Obstructive Pulmonary Disease (COPD) patients. Thirty patients (age 52 ± 0.66 years; body mass 66.15 ± 0.75 kg; height 176.17 ± 2.45 cm) with COPD were included in the study. The study used the experimental method by designing a three-month exercise rehabilitation program and using specific exercises to help patients reduce shortness of breath and strengthen their inspiratory and expiratory muscles. The current study was conducted at Babylon's pulmonary rehabilitation center. The Forced Expiratory Volume in the first second (FEV1), the Maximum Inspiratory Pressure (PImax), the maximum expiratory pressure (PEmax), and shortness of breath were all measured. The result shows that the difference in the shortness of breath (Borg Scale) between the pre and post-tests is insignificant at the error rate (5%). Furthermore, the value of calculated T (1.66) is smaller than the value of tabular T (2.57), indicating that there has been no improvement in the level of shortness of breath for the control group.
The difference in the level of shortness of breath shown in the table is significant at the error rate (5%). Furthermore, the pre- and post-tests are calculated as T(3.24), greater than the value of tabular T (2.57). Exercise rehabilitation altered FEV1, PImax, PEmax, and shortness of breath in COPD patients in the experimental group, pre-and post-tests supporting the experimental community, suggesting that physical activity affected FEV1, PImax, PEmax, and shortness of breath. According to our study, physical exercise improves COPD patients' respiratory muscles. This study concluded that patients expressed a desire to continue the exercise.
Keywords: physical exercise, breathing muscles, COPD patients.
Outdoor activities and outdoor environments for fitness and mental health: a systematic review
Authors: Nugraha Hartman , Hernawan Hernawan , Ali Masnur , Rahmat Ayi , Septianto Irvan , Aryati Aryati , Suryadi Didi
Published: August 2024

Outdoor activities and outdoor environments have been recognized as important factors in supporting fitness and mental health. This study aims to review the existing literature on the effects of outdoor activities and outdoor environments on fitness and mental health through a systematic review method. Mental health disorders are a leading cause of global disability, while physical fitness is important for activities without significant fatigue. Several studies have shown that physical activity provides significant benefits to physical, emotional and psychological well-being. The search strategy used Science Direct, Pubmed, and Scopus databases following PRISMA guidelines. The search yielded 4,917 publications, but after the selection process, only seven articles met the inclusion criteria. The studies analyzed also showed that regular engagement in outdoor activities can contribute to improved physical fitness, including increased muscle strength and cardiovascular fitness. In terms of mental health, outdoor activities are associated with reduced levels of anxiety and depression, as well as increased self-confidence and life satisfaction. This research highlights the importance of designing and implementing fitness programs that take advantage of the outdoor environment, as well as encouraging people to engage in regular outdoor activities. The study also highlights the importance of outdoor nature-based interventions to improve fitness and mental health in adults and adolescents. These conclusions provide a basis for policy makers and health practitioners to promote the use of outdoor environments as a means to improve fitness and mental health. The findings can serve as a basis for developing effective health promotion strategies through interactions with nature.
Keywords: Physical activity, outdoor activity, fitness, mental health
Mortalidade e comportamento do gorgulho-do-milho exposto a diferentes produtos naturais
Authors:   , Carvalho Núbia Eliza de Azevedo
Published: August 2024

O gorgulho-do-milho (Sitophilus zeamais) causa problemas fitossanitários no armazenamento de commodities agrícolas, o seu controle é realizado, com o uso de inseticidas sintéticos, no entanto, tem crescido a busca por produtos alternativos para o controle destas pragas, dentre as alternativas, destacam-se os compostos naturais derivados de plantas. O objetivo foi avaliar os efeitos dos produtos naturais no tratamento de grãos para o controle do gorgulho-do-milho, foi realizado 3 testes: toxicidade, comportamental e a chance de escolha. O teste de toxicidade avaliou diferentes concentrações do Original Nim®, estragão, Trans-anetol, Funcho-doce e Óleo de Cravo e o controle com acetona, a fim de obter a concentração letal de 50% e de 90%. No teste comportamental, utilizou as concentrações obtidas, e avaliou período de latência, frequência da caminhada, número de visitas e tempo de permanência, além da preferência dos insetos pelos grãos tratados. Os maiores valores de concentração letal foram do Original Nim ® (2,28 μL. L-1), e do Óleo de Cravo (2, 28 μL. L-1) e os menores foram do Trans-anetol (0,22 μL. L-1), do Funcho- doce (0,24 μL. L-1) e do estragão (0,25 μL. L-1). No comportamento, o número de visitas do cravo (1 visita), do nem (2,33) e do funcho (1) diferiram significativamente, da mesma forma a frequência da caminhada do funcho e o cravo com os menores valores (2; 1,33), respectivamente. Na chance de escolha, com a concentração letal de 50%, a preferência pelo Original Nim® foi significativamente maior do que nos demais tratamentos, tanto em 24 horas, com 24,5%, quanto em 48 horas, 29% de preferência. No tratamento com 90%, em 48 horas, o Original Nim® diferiu significativamente com 17,5%. Estes resultados indicam a concentração letal de 50 e 90% dos produtos naturais para o controle do gorgulho-do-milho, e foi possível avaliar o comportamento do inseto quando tratado a massa, esses produtos demonstram ser uma promissora alternativa para reduzir os danos qualitativos e quantitativos nos grãos. Palavras-chave: Produtos naturais; Gorgulho do milho; Azadiractina; Comportamento de inseto; Toxicidade.
Editorial - O Direito Internacional e Europeu Face à Invasão da Ucrânia - Um Ano Depois
Authors: Lanceiro Rui , Gil Ana Rita , Kaplina Vladyslava
Published: August 2024

Em 24 de fevereiro de 2022, a Federação Russa lançou uma invasão militar em larga escala na Ucrânia, naquilo que chamou uma “operação militar especial”, mas que foi qualificada pela A.G. das Nações Unidas como uma agressão a um Estado soberano durante uma sessão especial de emergência, que teve início no dia 28 de Fevereiro de 2022 – apenas a 11.ª sessão desse tipo convocada desde a fundação das Nações Unidas. A invasão em larga escala russa foi a sequência do conflito armado interestadual nas regiões de Donetsk e Luhanks, que começou em 2014 com a anexação da Crimeia pela Rússia. Nas semanas que se seguiram a invasão militar, assistiu-se a uma multiplicidade de ocorrências que marcaram o palco internacional: à continuação e agravamento dos ataques levados a cabo pelas tropas russas, à defesa incansável do território por parte das autoridades e cidadãos ucranianos, a uma crise humanitária de deslocados que rapidamente ascendeu a vários milhões, à condenação da agressão por parte da esmagadora maioria dos membros da comunidade internacional, à imposição de sanções à Federação Russa por parte de diversas organizações internacionais e à pronúncia de tribunais internacionais sobre o conflito, entre outros.
Judicial relief in war times? Ukraine vs. Russia (2022) before the International Court of Justice
Authors: Gil Ana Rita
Published: August 2024

The article examines the phenomenon of human rights due diligence in conflict-affected and high-risk areas through the example of Ukraine. It is stressed that in conflict-affected and high-risk areas the companies should conduct heightened human rights due diligence, which complements the ‘classical’ ongoing due diligence with conflict-sensitive approach. Using the data presented by Business & Human Rights Resource Centre, the article shows that, unfortunately, companies have not implemented heightened human rights due diligence into their activities in Ukraine and/or Russia after the beginning of full-scale military invasion in February 2022. Besides, the article highlights that the companies should constantly evaluate the ongoing conflict and/or high-risk area, since the situation may change rapidly. This has been proved by the fact that the recently announced partial mobilization in Russia jeopardizes companies and increases the risk of them being found complicit in war crimes committed in Ukraine. Conclusions present quick step-by-step advice on how to conduct heightened human rights due diligence in conflict-affected areas.
Reserva de lei parlamentar e autodeterminação de género – Comentário ao Acórdão n.º 474/2021 do Tribunal Constitucional
Authors: Fabiao Gonçalo
Published: August 2024

No Acórdão n.º 474/2021, o Tribunal Constitucional declarou a inconstitucionalidade com força obrigatória geral de normas sobre o direito fundamental à autodeterminação de género fundamentando-se na reserva de lei parlamentar. Neste artigo procura-se esclarecer o que compreende a reserva de lei parlamentar e, a partir daí, confrontar a decisão do Tribunal Constitucional com um conjunto de argumentos jurídicos que aquele não considerou na sua decisão.
Comentário ao Acórdão n.º 123/2021, de 15 de Março (Eutanásia)
Authors: Pereira Coutinho Luis
Published: August 2024

O Acórdão n.º 123/2021, de 15 de Março (Eutanásia) refere à dimensão objetiva dos direitos fundamentais um sentido restritivo da respetiva dimensão subjetiva, o que é muito problemático. Ainda mais problemática é a radicação do Tribunal Constitucional, a respeito do princípio da dignidade da pessoa humana, em pressupostos de filosofia moral que são fortemente discutidos num contexto de pluralismo mundividencial. A redução teleológica da inviolabilidade da vida humana feita pelo Tribunal não se pode, pois, sustentar-se nesses termos. Não seria também admissível a radicação do Tribunal constitucional num pretenso "direito comum europeu".
The “Cosmopolitan” Legislative Regions of Europe: Some comparative lessons from the participation of the REGLEG in Portugal
Authors: Sousa da Cunha Ricardo
Published: August 2024

The present paper is the result of the participation in the Conference on Multilevel Legislative Drafting and Legislative Impact Assessment, held in Lisbon on the 15th of June 2022. The participation of the legislative regions (REGLEG) in the multilevel legislative drafting of the EU was questioned in Portugal over the transposition of Directives by the Autonomous Region of the Azores, in a procedure that was adjudicated by the Portuguese Constitutional Courts. This was the pretext for this presentation, aimed at discussing the legislative role of the REGLEG in the EU, which necessarily happens within the broader context of an increasingly cosmopolitan global legal order in multilevel networks of government.
Post-Legislative Scrutiny in Indonesia: A Misconception and Proposed Solutions
Authors: Ahlan Sjarif Fitriani , Wahyu Saputro Aditya , Jordi Kastanya Efraim
Published: August 2024

The post-legislative scrutiny’s problem lies in the misunderstood definition of evaluation, the implementing agency, and in the drafting of review questions in the evaluation process. This article argues, first, that the definition of monitoring and evaluation of law is reviewing law effectiveness, not including its legal or ideological compatibility with the constitution as in a preparatory process of law-making or a judicial review. Second, the evaluating agency should be both the legislature and the president, who hold equal law-making power in the case of Indonesia. Third, the review questions can be drafted from the law-making process indicated not only in Hansard, academic drafts (white paper), and meeting minutes, but also in the law-purpose provisions stipulated under the reviewed law. The authors will also conduct comparisons to other countries’ practices in proposing PLS for Indonesian legislative drafters and governmental stakeholders.
Metodologia de Identificação e Análise de Gold-Plating na Transposição de Diretivas Europeias
Authors: Cabugueira Manuel , Farinha Martim
Published: August 2024

O fenómeno de Gold-Plating na transposição de diretivas pelos Estados-Membros é muito discutido na OCDE e na União Europeia. O aproveitamento do momento de transposição pelo legislador nacional para “ir além da diretiva” (incluindo novas obrigações, estendendo os seus efeitos ou não aproveitando derrogações), pode ser considerado uma prática legislativa pouco transparente, que pode criar custos e entraves inesperados ao funcionamento do mercado interno. No entanto, faltam ferramentas próprias para a análise deste fenómeno e para compreender os seus efeitos junto dos cidadãos e empresas. No âmbito do projeto LegImpact, procurámos desenvolver uma metodologia para a identificação, análise e classificação de ocorrências da prática de Gold-Plating, consoante vários parâmetros (incidência, tipo de obrigação, tipo de impacto, prazo de transposição, produção de efeitos, etc.).
A Eficácia Retroativa dos Atos Administrativos Renovatórios Praticados em Execução de Sentenças Anulatórias
Authors: Penacho Fraga Diana
Published: August 2024

No âmbito da execução de sentenças anulatórias de atos renováveis — isto é, atos que, depois de anulados, podem ser praticados de novo sem reincidir no(s) vício(s) determinante(s) da sua anulação, normalmente vícios de legalidade externa —, foi permitido à Administração executar as mesmas através da prática de um ato renovatório retroativo, ou seja, de um ato administrativo retroativo, idêntico ao ato anulado, que não reincida nos vícios determinantes daquela anulação. A retroatividade deste ato está sujeita a limitações e só pode operar em determinados casos. Este artigo propõe-se a analisar os contornos da admissibilidade da retroatividade destes atos, no sentido de perceber em que casos esta é admissível e se, para o efeito, se deverá adotar uma posição mais ou menos restritiva quanto à sua admissibilidade.
The impact of (the absence of) recognition on the use of force
Authors: Corten Olivier , Koutroulis Vaios
Published: August 2024

The impact of (the absence of) recognition of an entity as a State on the application of the prohibition to use force relates to the personal scope of application of the prohibition to use force. So far, it has not been analysed in-depth, many writings focusing rather on the possibility to invoke self-defence against non-state actors. Referring to the explanatory note to article 1 of resolution 3314 as interpreted by existing practice (notably the Russian-Ukrainian War), the authors argue against the possibility to invoke any (absence) recognition as a valid justification to use of force.
Ius Post Bellum obligations on protection of displaced persons: making a case for the responsibility of States intervening in armed conflicts
Authors: Gil Ana Rita
Published: August 2024

International Law’s responses on protection of internationally displaced persons fleeing conflicts are traditionally grounded on International Refugee Law. However, this branch of Law presents several gaps in this context: namely, apart from special arrangements, it does not assign a specific responsibility on protection of displaced civilians to any State in particular. On the other hand, traditional theories on State’s responsibility on displacement mainly focus on the responsibility of the State of origin. In this paper, I argue that ius post bellum may be used to assign specific responsibilities on protection to the States that intervened in such conflicts. The paper discusses the concept of “intervening State” and then elaborates on which States may be deemed as “responsible”. Finally, several possible ways of protection will be put forward, departing from the current International Law’s responses in this regard.
State’s reactions to attacks by Houthis as a testbed for the use of force against non-State actors
Authors: Fernandes Mário João
Published: August 2024

Attacks perpetrated, since November 2023, by Houthis, in the Red Sea, against commercial and military vessels raise interesting questions on the qualification of the use of force. On-the-spot self-defence against Houthi armed attacks taking place in the high seas is lawful. Further action against inland Houthis revisits the much discussed admissibility of the use of force against non-State actors (under Article 51 of the Charter, self-defence is designed to be exercised against States) and the requirements of self-defence. The UN Security Council has been following the Yemeni civil war, but no authorisation was granted for the use of force against Houthis. No invitation to intervene was addressed by Yemen to any of the States claiming self defence against inland Houthis in response to recent naval attacks. Self-defence against inland Houthis, if unopposed by the territorial State, may be lawfully construed as an act against a de facto Government.