bluuebunny/crossref_metadata_2025 huggingface dataset:
Innovative education approaches by geriatric pharmacists and their training needs: A systematic review
Authors: Nurfauzi Yuhansyah , Wahyono Djoko , Rahmawati Fita , Yasin Nanang Munif
Published: January 2021

Purpose: To undertake a systematic review designed to observe the educational activities carried out by geriatric pharmacists innovatively, and also to ascertain their training needs.Methods: Articles were selected based on the following inclusion criteria: published in the years 2000 - 2019, designed as a randomized controlled trial (RCT), published in English language, contained educational activities carried out by pharmacists, and contained training requirements for pharmacists. The exclusion criteria were as follows: did not mention educational activities, only examined and assessed economic aspects, and used qualitative studies. This study analyzed nine articles from PUBMED, Scopus and Google Scholar that met the inclusion criteria.Results: Comprehensive education consisting of approaches such as interviews, discussions, case conferences, demonstrations, and goal-setting techniques provided innovations to medication review and pharmaceutical care plans. Seminar and e-learning were approaches to innovative problem-based education. Pharmacists needed training on medication review, education techniques for geriatrics, clinical collaboration, and geriatric pharmacotherapy.Conclusion: Pharmacist chose comprehensive and problem-based education approaches innovatively which require training in treatment management as well as professional relationship skills as educators, and based on the perspective of elderly needs.

Keywords: Geriatric, Pharmacist, Education, Training, Innovative approaches
Baicalein inhibits cell development in papillary thyroid cancer by regulating miR-206/RAP1B pathway
Authors: Wang Peng , Guo Liang , Liang Zhong , Lou Jianlin , Zhao Jianqiang
Published: January 2021

Purpose: To investigate the therapeutic effect of baicalein on papillary thyroid cancer (PTC) cells in vitro and its underlying molecular mechanism.Methods: The human PTC cell line TPC-1 was divided into five groups and treated with distilled water or baicalein at 10, 20, 50, or 100 μM. Next, miR-206, miR-206 inhibitor, the respective negative controls of miR-206 and miR-206 inhibitor, RAP1B small interfering RNA (siRNA), and control vector siRNA were synthesized and transfected into TPC-1 cells. Cell viability, migration, and invasion were measured using the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) and Transwell assays. miR-206 expression and Ras-related protein (RAP1B) levels were assessed by quantitative real-time reverse transcription-polymerase chain reaction and western blotting, respectively.Results: Baicalein inhibited TPC-1 cell viability, migration and invasion, upregulated miR-206 expression, and reduced the RAP1B level in a concentration-dependent manner (p < 0.01). miR-206 negatively regulated RAP1B expression and increased the baicalein-induced reduction of RAP1B expression. Moreover, RAP1B overexpression relieved the suppression of cell viability, migration, and invasion caused by baicalein (p < 0.01).Conclusion: Baicalein suppresses cell growth in PTC cells by regulating the miR-206/RAP1B pathway, providing a new therapeutic strategy for PTC treatment.

Keywords: Baicalein, Papillary thyroid cancer (PTC), miR-206, RAP1B, Cell viability, Cell invasion
Deltex E3 Ubiquitin Ligase 3L confers radioresistance in prostate cancer via Akt pathway
Authors: Xiang Junyi , Lv Bodong , Fan Shufeng , Zhang Zhitian , Yang Hui
Published: January 2021

Purpose: To determine the effect of Deltex E3 Ubiquitin Ligase 3L (DTX3L) on the radioresistance of prostate cancer (PCa).Methods: A PCa cell model of radioresistance was established via exposure of cancer cell lines to fractionated radiation. The MTT {(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide)} assay and western blotting were performed to evaluate the impact of DTX3L on cell survival and DNA damage repair. The molecular mechanism of action was evaluated by western blotting.Results: DTX3L was elevated in PCa cell lines compared with normal primary prostate epithelial cells (p < 0.01). The survival of PCa cells exposed to radiation was promoted by overexpression of DTX3L, while knockdown of DTX3L abrogated the radioresistance. Moreover, overexpression of DTX3Ldecreased phosphorylation of histone H2AX (γH2AX) and increased Rad51 levels (p < 0.01). However, knockdown of DTX3L reversed the accumulation of γH2AX and Rad51. Phosphorylation of AKT was promoted by DTX3L overexpression, but was reduced by DTX3L knockdown (p < 0.01). Inhibition of AKT (protein kinase B) counteracted the promotion ability of DTX3L on the radioresistance of PCa cells via decreased cell survival ratio, and also inhibited DNA damage repair via accumulation of γ-H2AX and depletion of Rad51 (p < 0.01).Conclusion: DTX3L increases the resistance of prostate cancer to radiotherapy and DNA damage repair in PCa via AKT pathway, indicating a potential therapeutic strategy to overcome radioresistance in PCa.

Keywords: DTX3L (Deltex E3 Ubiquitin Ligase 3L), DNA damage, Phosphorylation, Radioresistance, AKT, Protein kinase B, Prostate cancer
Gastroprotective effect of the root extract of Alpinia officinarum Hance (Zingiberoside) against acute indomethacin-induced gastric injuries in rats: Involvement of H+/K+-ATPase and prostaglandin E receptors
Authors: Gong Jingwen , Zhang Xuguang , Tan Yinfeng , Li Hailong , Hou Jie , Zhang Junqing
Published: January 2021

Purpose: To investigate the protective effects of Alpinia officinarum root ethanol extract (AOE) and galangin against acute indomethacin-induced injury on rat gastric mucosaMethods: Sprague-Dawley rats were daily treated with bismuth potassium citrate (0.08 g/kg), AOE at doses of 0.09, 0.18 and 0.36 g/kg; and galangin (0.2 g/kg) for 15 days. Then, gastric injury on rats was induced by intragastric administration of indomethacin (30 mg/kg). Blood flow and thickness of gastric mucosa were determined using neutral red clearance test and Alcian blue staining. The activity of H+/K+-ATPase was assayed using a biochemical kit. Prostaglandin E receptor expressions were assayed by western blotting.Results: High doses of ethanol extract of Alpinia officinarum root significantly inhibited H+/K+-ATPase activity by 8.12 % (p < 0.01), increased gastric mucosal blood flow (p < 0.001), enhanced mucus thickness (p < 0.05), and elevated the activities of prostaglandin E receptors 1 and 4 (p < 0.05).Galangin significantly inhibited H+/K+-ATPase activity by 4.82 % (p < 0.05) and increased gastric mucosal blood flow (p < 0.01).Conclusion: The ethanol extract of Alpinia officinarum root attenuates indomethacin-induced gastric injury by reinforcing gastric mucosal barrier and inhibiting excessive gastric acid secretion. Thus, the extract can be potentially developed for management of gastric injuries.

Keywords: Galangin, Gastric mucosal barrier, Gastric acid, Prostaglandin, Indomethacin
Saussurea lappa Clarke extract exhibits potent antioxidant effect and attenuates neuroinflammatory responses in lipopolysaccharide-stimulated microglial cells
Authors: Lee Sung-Gyu , Kang Hyun
Published: January 2021

Purpose: To investigate the antioxidant and anti-neuroinflammatory potential of Saussurea lappa Clarke (SLC-EA) extract in LPS-stimulated BV-2 microglial cells.Methods: Cell viability was measured by using the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay while antioxidant activity was evaluated by using the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity. Lipopolysaccharide (LPS) was used to stimulate BV-2 microglia. Griess assay was employed to assess nitric oxide (NO) production. iNOS (inducible NO synthase) expression and TNF-α (tumor necrosis factor-alpha) cytokine production were measured by ELISA (enzyme-linked immunosorbent assay) and immuno blot analysis, respectively.Results: Pretreatment of 100 mg/ml of SLC-EA (p < 0.001) was inhibited Nitric Oxide (NO) by 1 ug/ml of LPS-treated murine BV-2 cells. The expression of iNOS and TNF-α were reduced by SLC-EA concentration dependent manner (p < 0.001 at 100 mg/ml). SLC-EA were scavenged 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radicals in a dose-dependent manner with an IC50 value of approximately 51.4 μg/ml.Conclusion: The results indicate that SLC-EA extract exhibits strong antioxidant properties and inhibits excessive pro-inflammatory cytokine due probably to the antioxidant phenolic compounds present in SLC-EA extract. Further work in exploring the in-depth mechanisms of SLC-EA extract in regulating inflammatory signaling pathways in treating neuroinflammatory diseases is necessary.

Keywords: Saussurea lappa, Antioxidant, Neuroinflammation, Microglia, TNF-α, iNOS
Mitigating effect of metformin on polycystic ovarian syndrome and insulin resistance in rats, and the mechanisms involved
Authors: Hu Lanyawen , Wang Baimiao , Tao Yingli
Published: January 2021

Purpose: To study the effect of metformin on polycystic ovarian syndrome (PCOS) and insulin resistance (IR) in rats, and the mechanism involved.Methods: Eighty healthy female SD rats, aged 6 weeks, were selected. Three groups of rats were used: model, metformin + PI3K inhibitor, and metformin groups, with 20/group. Testosterone, leutenizing hormone (LH), and follicle-stimulating hormone (FSH) were assayed by enzyme-linkedassay (ELISA), while HOMA-IR was calculated from fasting blood sugar (FBG); the effect of metformin on the IR of PCOS rats was determined. The expressions of PI3K and AKT in ovaries and liver of rats in each group were assayed by Western blotting.Results: Fasting blood glucose, fasting insulin, and insulin resistance index were markedly higher in model than in control rats, and also significantly higher in inhibitor-treated rats than in metformin rats (p < 0.05). Relative to control, FSH level was higher, while levels of LH, LH/FSH ratio and testosterone in the metformin group were significantly lower (p < 0.05). The expression levels of PI3K and AKT in the ovary and liver were reduced in the inhibitor group, relative to the levels in metformin-treated rats (p < 0.05).Conclusion: Metformin mitigates PCOS-linked ovarian changes and IR in rats via PI3K/AKT route. These findings may be useful in the design of new drugs.

Keywords: Metformin, Polycystic ovary syndrome, Leutenizing hormone, Insulin resistance, Fasting blood sugar, Follicle-stimulating hormone
Effect of Wu-Wei-Gui-Shao decoction on complete Freund's adjuvant-induced arthritis rats
Authors: Zhang Maoquan , Liu Baolong , Ji Zonghui
Published: January 2021

Purpose: To investigate the anti-rheumatic potential of Wu-Wei-Gui-Shao decoction (WGD) and its possible mechanism of action.

Methods: Adjuvant arthritis (AA) rats were established using complete Freund's adjuvant. The rats were then given different doses of WGD (100, 200, and 400 mg/kg, for 28 days). The anti-arthritic effects of WGD were evaluated. Furthermore, the in vitro anti-arthritic effects of WGD and its related mechanisms were also determined in MH7A cells.

Results: WGD (100 - 400 mg/kg) exhibited significant anti-rheumatic properties after 28 days of treatment, inhibiting paw edema in AA rats, reducing arthritis score and thymus and spleen index, and inhibiting the tumor necrosis factor (TNF)-α and the interleukin (IL)-6. In addition, the results of in vitro cell experiments also confirmed that WGD reduced the release of cytokines, as well as mRNA levels of matrix metalloproteinase (MMP) -2, -3, and -9.

Conclusion: These findings suggest that WGD can be further developed as a traditional Chinese medicine to treat rheumatic arthritis.

Keywords: Wu-Wei-Gui-Shao decoction, Complete Freund's adjuvant, Arthritis, Molecular mechanism, Traditional Chinese Medicine
Echinacoside attenuates lipopolysaccharide-induced acute lung injury in newborn mice via inactivation of NF- κB/NLRP3 signaling pathway
Authors: Fu Meijiao , Shen Tong , Yang Ying , Zheng Yaling , Zhong Lilin
Published: January 2021

Purpose: To investigate the effect of echinacoside (ECH) on acute lung injury (ALI) and the underlying mechanism of action.Methods: The ALI model was established through intranasal instillation of lipopolysaccharide (LPS). Lung tissue damage was determined using hematoxylin and eosin (H&E) staining and lung wet-to-dry–weight ratio. Bronchoalveolar lavage fluid (BALF) protein concentration, cell count, and cytokine level were evaluated. Western blotting was used to determine protein expression level.Results: ECH attenuated lung tissue injury and lung wet-to-dry–weight ratio in the ALI model (p < 0.01). The total protein content and number of total cells, neutrophils, and macrophages increased in BALF of mice treated with LPS, but these increases were reversed by ECH treatment (p < 0.01). The levels of TNF-α and IL-1β increased in BALF and lung tissue of LPS-treated mice; however, ECH treatment decreased these changes (p < 0.01). In addition, ECH inhibited the activation of the nuclear factor-κB (NF-κB)/NLR family pyrin domain containing 3 (NLRP3) pathway in LPS-treated mice (p < 0.01).Conclusion: Echinacoside attenuates LPS-induced ALI via inactivation of the NF-κB/NLRP3 pathway, making echinacoside a potential drug for the treatment of ALI.

Keywords: Echinacoside, Acute lung injury, Lipopolysaccharide, Nuclear factor-κB, NLR family pyrin domain containing 3
MiR-148a-3p suppresses the progression of gastric cancer cells through targeting ATP6AP2
Authors: Jin Xiaosheng , Cai Peipei , Shi Zhengchao , Ye Fangpeng , Ji Tingting , Li Rongzhou
Published: January 2021

Purpose: Gastric cancer (GC) is one of the most frequent tumors with high mortality rate, worldwide. A proper understanding of the mechanism  underlying its progression is required for its diagnosis and development of novel treatment option. MicroRNAs are associated with the development and advancement of different types of cancer, including GC. The current research was aimed at investigating the molecular and biological function of miR-148a-3p in GC development.Methods: A human normal gastric epithelial cell line, GES-1 (control) as well as four GC cell lines (NUGC-4, SNU-520, STKM-2 and MKN-74) were employed for the study. MiR-148a-3p and ATP6AP2 expression levels in GC cell lines were examined by RT-qPCR technique. Transfection procedure was used to upregulate miR-148a-3p expression in the MKN-45 cell line. MTT assay was utilized to evaluate cell viability in GC cell lines. The molecular interaction between miR-148a-3p and ATP6AP2 was predicted using bioinformatics system and the prediction was then validated by luciferase reporter assay.Results: Expression levels of miR-148-3p was low, whilst that of ATP6AP2 was high in GC cell lines. MiR-148a-3p overexpression resulted in the reduction of cell viability in GC cell lines. More so, it was confirmed that miR-148-3p, as a post-transcriptional regulator inhibited ATP6AP2 expression by having a negative association with it in GC cells. More so, ATP6AP2 was found to be a direct target of miR-148a-3p.Conclusion: Our results revealed that miR-148a-3p plays a crucial function in GC development through targeting ATP6AP2. This finding could be explored in the discovery of new therapeutic approaches for GC treatment.

Keywords: ATP6AP2, Cell viability, Gastric cancer, miR-148a-3p, Progression
Infective endocarditis: prevention and antibiotic prophylaxis
Authors:   Swiss expert group on infective endocarditis prevention
Published: January 2021

After considerable revision of the previous guidelines on infective endocarditis prophylaxis by the American Heart Association in 2007, the Swiss recommendations were revised and published accordingly in 2008. The Swiss societies of Infectious Diseases (SSI), Pediatric Cardiology and Cardiology and the Pediatric Infectious Disease Group of Switzerland present the current update in a joint initiative.
Exploring bike-sharing systems in Poland co-financed from the European Union funds
Authors: Dzięcielski Michał , Woźniak Marcin , Radzimski Adam
Published: January 2021

In recent years, numerous Polish cities and municipalities have become involved in the creation of bike-sharing systems. Although the contribution of bike-sharing to creating sustainable transport caused some controversy in the literature, the positive role of cycling in promoting low-emission mobility and a healthy lifestyle is widely acknowledged. As part of the European Union’s sustainable transport agenda, some Polish local governments have obtained funding from structural funds for the implementation of bicycle-sharing schemes. This article presents an overview of selected systems, as well as a preliminary analysis of their users’ activity based on data obtained through a Web API. Although the scope of the data was limited in time due to the shutdown of the systems caused by the COVID-19 pandemic shortly after their spring reactivation, some patterns could be observed. In particular, users activity was more evenly distributed over time in larger cities (over 300 thousand of residents), whereas in smaller cities alternating periods of high and low activity was observed.
Multicriterial analysis of the accessibility of public transport stops in Cracow
Authors: Bárta Martin , Masopust Tomas
Published: January 2021

This study deals with the synthesis of selected attributes of public transport accessibility. The aim is to present a new method of multi-criteria analysis. As the research area, the city of Cracow has been chosen. The GTFS (General Transit Feed Specification) system has been used to obtain traffic data for buses and trams within the city‘s transport company (MPK Krakow). The analysis itself consists of 4 main accessibility indicators (walking time to each stop, number of lines, directions, and connections from each stop). The problem of exceeding the stops accessibility beyond the administrative border of Cracow has been solved by using a 500 m wide buffer zone around the city. To connect the individual layers of indicators into a multicriteria analysis, the Voronoi diagram function has been applied. The results of the method are presented in the form of synthetic maps of transport accessibility for each bus and tram stop in Cracow. Together with the synthetic accessibility maps, an index of a stop importance has been created as well, which consists of the sum of the mean percentages from 3 indicators (number of lines, directions, connections). The synthetic method used and acquired detailed values not only for the city of Cracow as a whole, but also its individual parts make it possible to provide a comprehensive picture of accessibility by public transport. This multicriteria analysis can also be extended for a comparative study of selected cities.
Applications of artificial neural network and Box-Behnken Design for modelling malachite green dye degradation from textile effluents using TiO2 photocatalyst
Authors: K.C Chandrika , Prabhu T. Niranjana , Kiran R. R. Siva , Krishna R. Hari
Published: January 2021

Most of the photocatalytic studies for pollutant degradation are based on optimizing a single parameter that results in a non-linear relationship between the overall parameters and the photo-degradation reactions. To address this critical problem, herein, we report the use of Response Surface Methodology based on the Box-Behnken Design (BBD) for modeling the photocatalysis degradation of Malachite Green (MG) dye using nano TiO2 as photocatalyst. The catalyst characterizations are carried out using XRD, SEM, and TEM, indicating that the TiO2 prepared by sol-gel synthesis possesses Anatase phase with particles in the nano regime and porous surface morphology. The optimum operating conditions for degradation of MG was identified by the interactive effects of variable factors such as initial dye concentration 10-30 ppm (x1), catalyst dosage 1-3 mg (x2), contact time 20-60 min (x3) using the Box-Behnken method. Furthermore, the degradation reactions are also evaluated by Artificial Neural Networks (ANN). Their predicted results have been validated by the experimental studies and found to be acceptable. Their optimal results to achieve 90% degradation efficiency at TiO2 nanoparticle dosage (3 mg), reaction time (60 min), and initial dye concentration (20 ppm) have been validated by the experimental studies and found to be acceptable.
Fuzzy Functional and Multivalued Dependencies for Frank’s Class of Additive Generators
Authors: Nesimovic Sanela , Gusic Dzenan
Published: January 2021

In this paper we consider all possible dependencies that can be built upon similarity-based fuzzy relations, that is, fuzzy functional and fuzzy multivalued dependencies. Motivated by the fact that the classical obtaining of new dependencies via inference rules may be tedious and uncertain, we replace it by the automated one, where the key role is played by the resolution principle techniques and the fuzzy formulas in place of fuzzy dependencies. We prove that some fuzzy multivalued dependency is actively correct with respect to given fuzzy relation instance if and only if the corresponding fuzzy formula is in line with the attached interpretation. Additionally, we require the tuples of the instance to be conformant (up to some extent) on the leading set of attributes. The equivalence as well as the conclusion are generalized to sets of attributes. The research is conducted by representing the attributes and fuzzy dependencies in the form of fuzzy formulas, and the application of fuzzy implication operators derived from carefully selected Frank’s classes of additive generators
Educación ambiental y pensamiento crítico en la sociedad actual
Authors: Portocarrero Gutierrez César Augusto , Zavaleta Llanos Nila Yusey , Costilla Ventura Néstor Yim , Adrianzen Viera Augusto
Published: January 2021

Se analizó los trabajos de investigación de los últimos 5 años para poder profundizar en el trabajo reciente. El objetivo de la presente investigación ha sido poder revisar los antecedentes en referencia al pensamiento crítico y el aporte en la cultura y el desarrollo de la educación ambiental en la sociedad actual. También el estudio quiere contribuir en analizar las características del pensamiento crítico y su acercamiento a la realidad ambiental. Además, desea fomentar la responsabilidad del cuidado ambiental de la sociedad en conjunto, contribuyendo en la cooperación social y su protección en el cambio ambiental que nos encontramos viviendo en la actualidad, permitiendo descubrir la importancia del pensamiento crítico en tiempos de crisis ambiental. El análisis del resultado es que el pensamiento crítico permite desarrollar en la sociedad responsabilidad ambiental, creando conciencia ambiental que se evidencia en la protección ambiental y el desarrollo de mecanismos ambientales en la protección.
The Spanish public pension system as opposed to the alternative of private pension plans
Authors: Cubas Pardo M.
Published: January 2021

Many countries are currently facing the problem of sustainability of public pension systems due to demographic developments and changes in the labor market. In this context, private pension plans are often presented as an alternative. This paper aims to describe the functioning of the current public pension system in Spain and the impact that abandoning the current public system and adopting a pension system based on private contributions would have on workers and pensioners. To this end, a hypothetical case study is presented, for an average worker, comparing the contributions made in each of the systems (public and private) as well as the benefits received after retirement. The results show the different nature of public pensions, which act as an insurance and have a strong redistributive component, as opposed to private pensions, which have an investment nature. For the average worker, the adoption of a private system would entail losses in the purchasing power during his working life and a very substantial reduction in the amounts received during retirement, along with greater economic instability.
An estimation of cost-based market liquidity from daily high, low and close prices
Authors: Saleemi J.
Published: January 2021

In the literature of asset pricing, this paper introduces a new method to estimate the cost-based market liquidity (CBML), that is, the bid-ask spread. The proposed model of spread proxy positively correlates with the examined low-frequency spread proxies for a larger dataset. The introduced approach provides potential implications in important aspects. Unlike in the Roll bid-ask spread model and the CHL bid-ask estimator, the CBML model consistently estimates market liquidity and trading cost for the entire dataset. Additionally, the CBML estimator steadily measures positive spreads, unlike in the CS bid-ask spread model. The construction of the proposed approach is not computationally intensive and can be considered for distinct studies at both market and firm levels.
Infective Endocarditis Caused by Streptococcus Mutans Following Tooth Extraction in a Patient with Undiagnosed Mitral Valve Prolapse Previously: A Case Report
Authors:   Department of Infectious Diseases, Namik Kemal University, Tekirdag, Turkey, Ilknur Erdem , Enes Ardıç ,   Department of Infectious Diseases, Namik Kemal University, Tekirdag, Turkey, Ritvan Karaali ,   Department of Infectious Diseases, Namik Kemal University, Tekirdag, Turkey, Seref Alpsoy ,   Department of Cardiology, Namik Kemal University, Tekirdag, Turkey, Sahin Topuz ,   Department of Cardiology, Namik Kemal University, Tekirdag, Turkey, M Enes Kardan ,   Department of Infectious Diseases, Namik Kemal University, Tekirdag, Turkey, Mustafa Dogan ,   Department of Infectious Diseases, Namik Kemal University, Tekirdag, Turkey, Selami Gurkan ,   Department of Cardiovascular Surgery, Namik Kemal University, Tekirdag, Turkey, Aynur Eren Topkaya ,   Department of Medical Microbiology, Namik Kemal University, Tekirdag, Turkey
Published: January 2021

Infective endocarditis is an acute or a subacute inflammatory infection of the endocardium caused by bacterial, viral or fungal microorganisms. Despite significant improvements in the diagnosis and treatment, it is still associated with a poor prognosis and a high mortality rate. Viridans streptococci are one of the most common causative microorganisms of bacterial endocarditis. Streptococcus mutans, a member of this group and is usually associated with dental carries. Although it is expected to be more frequently associated with endocarditis, has only rarely been reported. This is most likely to be due to some identification problems. We herein report a case of infective endocarditis due to Streptococcus mutans following tooth extraction with no history of heart disease.
Perfil dos praticantes de atletismo com incentivo ao esporte do município de Curitiba, Paraná
Authors: Sentone Rafael Gomes , Caregnato André Felipe , Cavichiolli Fernando Renato
Published: January 2021

O número de atletas pode estar relacionado com o sucesso esportivo em competições esportivas. No Brasil as entidades que administram o atletismo não possuem o registro dos atletas que praticam ou competem. Desta forma o objetivo da presente pesquisa foi identificar os atletas da modalidade de atletismo do município de Curitiba, Paraná por meio da análise da política pública de incentivo ao esporte da cidade. Utilizamos como método o levantamento dos atletas beneficiados por meio da Lei Municipal de Incentivo ao Esporte do Município entre os anos de 2002 a 2015, identificando o número de atletas, sexo e idade. Como resultados identificamos que a lei incentivou 106 atletas diferentes em todo o período dos quais 69 são homens e 37 são mulheres, com idade média de 34,4 anos e 39,1 anos, respectivamente. Concluímos que o número de atletas da modalidade de atletismo no município é pequeno e possuem idade média acima da considerada para atletas de rendimento esportivo.
Produção científica sobre as academias ao ar livre nos programas de pós-graduação no Brasil
Authors: Sousa Diego Petyk de , Oliveira Edilson de , Pinto Guilherme Moreira Caetano , Pedroso Bruno , Carmo Gonçalo Cassins Moreira do , Freitas Júnior Miguel Archanjo de
Published: January 2021

Em face a lacuna na produção existente sobre a sistematização do conhecimento das academias ao ar livre, o presente estudo tem por objetivo identificar as pesquisas que abordam o tema, e que foram produzidas no interior dos programas de pós-graduação do Brasil. Para tanto, foram realizados os procedimentos da revisão sistemática. Ao todo, 12 dissertações foram catalogadas após a etapa de coleta de dados. Por sua vez, a análise dos dados ocorreu por meio do Software Iramuteq. Verificou-se que a produção científica sobre o tema investigado ainda é recente e normalmente estudada em programas de pós-graduação em Educação Física. Ademais, a produção científica se concentra em dois grandes eixos: 1) o uso das academias ao ar livre; 2) a estrutura das academias ao ar livre. Com base nos resultados encontrados, conclui-se que a temática ainda precisa de um aprofundamento e desenvolvimento de novos estudos nos dois eixos supracitados, além da necessidade de pesquisas com o intuito de sustentar a formulação e reformulação de políticas públicas sobre as academias ao ar livre.
O perfil da produção brasileira educacional interdisciplinar sobre Educação Física
Authors: Lemke Cláudia Elizandra , Scheid Neusa Maria John
Published: January 2021

O presente estudo é uma revisão sistemática de literatura que tem como objetivo apresentar as produções educacionais de Interdisciplinaridade na área da Educação Física, procurando responder em qual região do país ocorrem mais publicações, em qual ano e quais os referenciais teóricos mais utilizados. Para isso, foram investigadas Teses e Dissertações na Biblioteca Digital de Teses e Dissertações, o indexador SciELO, os anais do FIEP e os periódicos da Área de Educação Física com estratos Qualis A1 e A2. Com um somatório de 121 trabalhos encontrados, podemos concluir que a região Sudeste, com 53 artigos, possui a maior produção sobre Interdisciplinaridade na Educação Física, com destaque para o ano de 2015, contendo a maior quantidade de publicações. Os referenciais teóricos mais utilizados foram as políticas públicas nacionais para a educação e as contribuições e/ou trabalhos de Ivani Fazenda.
University Student Volunteering (USV): Instruments for Its Comprehensive Diagnosis (ICD-USV)
Authors: Briones Elena , Salcines-Talledo Irina , González-Fernández Natalia
Published: January 2021

University Student Volunteering (USV) requires attention to guarantee its pedagogic quality and its fulfilment of community service. However, a review of the literature reveals a lack of tools for assessing the quality of USV. Thus, our research question was: how can we evaluate the efficacy of volunteer programs in higher education? This article follows a qualitative methodology through an evaluative case study of the creation of a set of instruments for the comprehensive diagnostic of USV (ICD-USV) with a 360° perspective, which provide feedback and feedforward for the development of USV, thus offering indicators of its quality. The application of the ICD-USV at a Spanish university and the participation of one volunteer student, five participating entities' technicians and two USV unit managers allowed for the identification of new analysis criteria for the adequate management of a USV program. Measures that could be used to guarantee the quality of basic, pedagogic, logistic and processual criteria, and to address the proposals and difficulties detected, are suggested.
Transição à democracia e os usos do passado recente para a legitimação de um novo regime político no México
Authors: Jacheta Riberti Larissa
Published: January 2021

Este artigo pretende debater o processo de transição à democracia no México à luz das mudanças políticas e institucionais e da atuação dos movimentos sociais que permitiram a vitória de Vicente Fox nas eleições 2000.  Nesse sentido, serão discutidos dois aspectos centrais desse processo: as  reformas políticas empreendidas a partir da década de 1970 pelos governos priistas e as lutas sociais configuradas desde pelo menos 1960 e que tenham sido capazes de repercutir as pressões pela democratização do Estado, pela mudança político-partidária e pelo deslinde de responsabilidades das violações cometidas nas décadas anteriores. Assim, busca-se apreender como o candidato à presidência de oposição fez uso das demandas por verdade, memória e justiça reivindicadas por organismos de direitos humanos e familiares de mortos e desaparecidos para construir uma plataforma política e uma coalização entre diferentes setores ideológicos em nome do tão esperado “giro político”.
ODRŽIVO KORPORATIVNO UPRAVLjANjE KAO USLOV DUGOROČNOG RAZVOJA PRIVREDNIH DRUŠTAVA
Authors: Mihajlovic Borko
Published: January 2021

Evropska komisija je oktobra 2020. godine u svom programu rada za 2021. godinu predvidela podnošenje niza zakonodavnih predloga u cilju postizanja održivog korporativnog upravljanja, koje predstavlja neophodan uslov održivog poslovanja privrednih društava. Osnovni predmet ovog rada upravo je analiza očekivanih, pretpostavljenih promena u pravnom regulisanju korporativnog upravljanja u EU. Ovu analizu autor je izvršio na osnovu zaključaka iznetih u studiji Evropske komisije o dužnostima direktora i održivom korporativnom upravljanju, koja će poslužiti kao osnov za sprovođenje najavljene reforme. Autor se u radu najpre, u kratkim crtama, bavi osnovnim osobinama koncepta održivog poslovanja privrednih društava i njegovom povezanošću sa održivim korporativnim upravljanjem. U središnjem delu rada, autor izdvaja promene koje smatra najznačajnijim delom buduće reforme: 1) promene u vezi sa institutom posebnih dužnosti direktora; 2) druge moguće izmene pravnog režima korporativnog upravljanja (izmene Direktive EU o pravima akcionara u cilju promovisanja dugoročnog investiranja i dužeg zadržavanja svojstva akcionara u istom privrednom društvu, promene vezane za sastav odbora direktora i mehanizme utvrđivanja naknada direktorima).
OS PROGRAMAS BRASILEIROS DE COMPLIANCE TRIBUTÁRIO SOB A PERSPECTIVA DA ISONOMIA ENQUANTO DIREITO FUNDAMENTAL
Authors: Martinho Jorge Eduardo de Souza
Published: January 2021

Este artigo trata da contextualização dos direitos fundamentais e da mudança de paradigma sobre a interpretação das limitações ao poder de tributar dispostas na Constituição, que passam a ser entendidas também como direitos fundamentais do contribuinte em face do Estado fiscal. Aborda-se, a partir deste embasamento teórico, a necessidade de transparência, confiança e diálogo na relação Fisco-contribuintes no Brasil, especialmente com os atuais programas de compliance tributário instituídos pela Receita Federal e pelo Estado de São Paulo, sob o prisma da isonomia tributária, enquanto direito fundamental do contribuinte.
O JULGAMENTO PELO STF DO RE N. 1.072.485/PR E A NECESSIDADE DE MODULAÇÃO DE SEUS EFEITOS
Authors: Lobato Valter de Souza , Teixeira Tiago Conde
Published: January 2021

Introdução. 1. Do instituto da Repercussão Geral. 2. Do RE n. 1.072.485/PR. 2.1. Do trâmite dos Recursos Extraordinários e reconhecimento da Repercussão Geral no STF. 2.2. Do julgamento do Tema n. 985 pelo Plenário do STF. 2.3. A extensão da coisa julgada e a sua suposta “flexibilização”. 3. Da (não) incidência de contribuição previdenciária patronal sobre o terço constitucional de férias. 4. Da alteração de jurisprudência promovida pelo RE n. 1.072.485/PR. 5. Proteção da confiança, boa-fé e segurança jurídica e sua relação com o Direito Tributário brasileiro. 5.1. Fundamentos da proteção da confiança. 5.2. A proteção da confiança no âmbito do Direito Público. 5.3. Proteção da confiança e irretroatividade. 5.4. A relação entre os princípios da segurança jurídica, boa-fé e proteção da confiança e a modificação de jurisprudência. Considerações Finais. Referências bibliográficas.
CONDOMÍNIOS EM TIME-SHARING: RESPONSABILIDADE TRIBUTÁRIA E SOLIDARIEDADE NO IPTU E NO ITR
Authors: Cunha André Luiz Ferreira
Published: January 2021

O presente artigo analisa a tributação da multipropriedade imobiliária no ordenamento jurídico brasileiro no que se refere à responsabilidade tributária e à solidariedade nos impostos sobre a propriedade predial e territorial urbana (IPTU) e territorial rural (ITR). Inicialmente, parte-se da apresentação histórica e conceitual acerca do instituto do time-sharing. Na sequência, o estudo prossegue com a exposição dos aspectos gerais dos dois impostos para, então, abordar os aspectos da responsabilidade tributária no tocante à multipropriedade, perpassando pela questão atinente à solidariedade, objeto central do trabalho. O problema será analisado, também, sob o enfoque dos princípios da legalidade, da igualdade, da capacidade contributiva e do direito fundamental à propriedade, garantias fundamentais que devem permear toda atividade hermenêutica. Por fim, passa-se à breve exposição das questões afetas à execução no tocante à penhora do bem imóvel sujeito ao condomínio em multipropriedade.
Retraso incrementado desde el diagnóstico hasta el tratamiento en pacientes venezolanos con artritis reumatoide.
Authors: Rodriguez Martin A. , Rodríguez-Polanco Elaudi , Rivero-Carrera Nardy , Serra-Bonett Natali , Al Snih Soham
Published: January 2021

Despite a decrease in time from disease onset to diagnosis, patients of a recent cohort had increased delay in initiation of first DMARD compared with patients from an earlier cohort, increasing the risk for disability in Venezuelan RA patients.
The Triumph of Left-wing Populism in Greece: Causes and Consequences
Authors: Demenko O.
Published: January 2021

The article analyzes the reasons and consequences of the spread of the ideology of left populism in Greece. It has been established that the success of the SYRIZA Coalition of Left Radical Forces, which was in power in Greece during 2015-2019, was facilitated by a number of factors. The most important among them: the popularity of leftist ideas in the social and political space of Greece; the traditions of populism inherent in most of the country’s political forces; unbalanced fiscal policy, structural macroeconomic imbalances, low statistical reliability and significant government debt; the world economic crisis of 2008-2009; deterioration of social standards and demographic indicators, the spread of unemployment; negative impact of the migration crisis; the tough position of Greece’s creditors, on whom public opinion blamed the country’s socio-economic problems.

It is noted that the phenomenon of left populism in Greece was the fact that immediately after the victory in the elections, SYRIZA, sandwiched between the demands of creditors and the real state of the economy, abandoned radical left populist ideas and was forced to pursue a neoliberal economic policy. Already in 2016, the country returned to slow economic growth, and in 2018 the financial assistance program was completed. However, due to the failure to fulfill its own campaign promises, SYRIZA lost power in the 2019 elections and took a centrist place in the Greek political system. A significant merit of the SYRIZA Coalition of Radical Left Forces was the successful resolution of an almost thirty-year dispute with North Macedonia over the name of the latter.

The opinion is substantiated that for Ukraine the main conclusion from the analysis of the Greek events of the early XXIst century is the realization of the fact that the complex problems of a political and socio-economic nature that face our country do not have a simple and quick solution. To achieve success, Ukraine must consistently defend its own national interests, strengthen sovereignty and independence, and pursue a balanced budgetary and financial and economic policy.
Faktor Berkah dalam Pola Konsumsi dan Tingkat Kepuasan untuk Pemenuhan Kebutuhan
Authors: Barokah Imam
Published: January 2021

A person can make a living with their needs. Needs are inseparable from humans. Every human being demands to be able to meet his needs. In its development, the needs always change according to an individual. Will increase and decrease according to the existing factors. Needs are more than desires that must be fulfilled before desires. Even though the two are different, some people consider them the same. People who are good at sorting will know the difference between desire and needs. This study discussed individual satisfaction with their needs, individual efforts to meet their needs, as well as identifying individual needs in a place. The data was collected through direct observation and interviews. This research was important for the community to know their needs. So that it can be seen directly the responsibility of the community regarding needs. From the data, it can be seen that there were different needs of the community and they also attach the important factor of the blessing.
Peramalan Data dengan Teknik Pemulusan Simple Moving Average (Studi Kasus Harga Saham Harian PT Bank BRI Syariah Tbk)
Authors: Yolanda Anne Mudya , Ridhwan M.
Published: January 2021

Time series analysis is used to model time series data and forecast data for future periods. This research was conducted to predict data with a simple smoothing technique, namely the Simple Moving Average of PT Bank BRI Syariah Tbk's stock closing price data. The closing price of shares was analyzed using three average criteria, namely 3, 5, 20, and 100 of the most recent data. Comparison of accuracy with SSE, MSE, and MAPE showed that the best in predicting daily stock closing price data was the Simple Moving Average using the latest 3 data with a prediction result for the future period of Rp. 748, -.
Kebijakan Fiskal pada Masa Rasulullah dan Sekarang
Authors: Karbila Ibnu Hasan , Helim Abdul , Rofii Rofii
Published: January 2021

This study aimed at distinguishing fiscal policy during the time of the Prophet and the fiscal policy prevailing in Indonesia. The study method in this research is literature study. The type of data used is secondary data with data collection methods through literature study. The results showed that during the time of the Prophet, the first fiscal policy that was taken after moving to Medina was to make muhajirin and ansar fraternal and provide employment for the Muhajirin. In the second year, almsgiving and fitrah are compulsory, followed by zakat in the ninth year of hijriyah. From here emerged fiscal policy instruments derived from zakat, infaq, alms and waqf. Some of these elements are mandatory and some are voluntary. Zakat is an element that must be paid after reaching the nisab, while infaq, alms and waqf are voluntary. This voluntary element is what distinguishes an Islamic economy from a capitalist economy. Another difference between the two is related to the management of state money where part of the APBN sources obtained from debt must be free from the element of interest, thus, the state debt can actually be obtained in ways that are in accordance with Islamic Sharia
Pengaruh E-Commerce terhadap Perilaku Konsumen dalam Perspektif Ekonomi Syariah
Authors: Afdila Afdila , Ferdinan Ferdinan
Published: January 2021

This study aimed at exploring whether e-commerce has an effect on consumer behavior in the perspective of Islamic economics in Islamic Economics students STAI Auliaurrasyidin Tembilahan. This research was motivated by the development of e-commerce as an online shopping application that has an impact on student consumer behavior. This study used a quantitative method with a simple linear regression analysis. The sample in this study was 146 respondents. In the simple linear regression test, the equation Y = 16.444 + 0.787 was obtained. Then from the t-test results obtained tcount (9.927) <ttable (1.976), so e-commerce has a significant effect on consumer behavior in the Islamic economic perspective. Based on the calculation of the coefficient of determination, the value is 0.406 or 40.6%. This data stated that the effect of e-commerce on consumer behavior in the Islamic economic perspective was 40.6%, while the remaining 59.4% was explained by other factors that were not observed in this study.
Is It Possible to Read Other People’s Confidence While Testing Their Implicit Learning?
Authors:   St. Petersburg State University, Savina Alina , Moroshkina Nadezhda ,   St. Petersburg State University
Published: January 2021

Recent studies have shown that observers can accurately read a partner’s confidence in their decision without verbal information exchange. The main question of the present study concerns the possibility of an accurate reading of the metacognitive experiences of others if they make decisions based on implicit knowledge. The second question addressed the predictors of such mindreadings if they are possible. The experiment was conducted using an artificial grammar learning paradigm. Participants worked in dyads: the Learner implicitly learned to classify stimuli as grammatical and non-grammatical, and the Observer observed the classification process while having no access to the stimuli, and not communicating with the partner. The Observer’s judgment of the Learner’s confidence, as well as the Learner's judgment of his/her confidence, were recorded. The results demonstrate that the Learner's confidence judgments correlate with the Observer's judgments of his/her confidence. Moreover, only the confidence judgments of the Learner correlate with the classification accuracy. It is concluded that intrapersonal confidence judgments and interpersonal confidence judgments are partially guided by the same criteria (in particular, response time), however, the Learners’ judgments of their own confidence in the decisions are more sensitive to the implicit knowledge
Model Pendampingan Pastoral Terhadap Perempuan Kristen Dalam Menghadapi Fase Pre-Menopause Di GPIN “Yerusalem” Palembang
Authors: Utari Lilik
Published: January 2021

Pendampingan pastoral adalah suatu pendekatan bagi setiap orang untuk mengetahui setiap kehidupan konseling oleh konselor. Tetapi berbicara tentang pendampingan pastoral Kristen itu berarti berbicara tentang bagaimana gembala melayani seseorang yang mengalami suatu masalah dalam hidupnya. Dimana dalam pelayanan ini ada beberapa pendekatan yang dilakukan, untuk bisa menemukan titik temu akan masalah yang dihadapi, terkhusus bagi seorang perempuan yang dilayani. Termasuk juga perempuan dalam lingkup gereja. Artikel ini juga akan memaparkan secara singkat tentang model pendampingan pastoral terhadap perempuan Kristen dalam menghadapi fase pre-menopause.