bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluasi Program Deradikalisasi Narapidana Teroris dalam Lembaga Pemasyarakatan
Authors: Bramudia Brahmana Farrel Carlo , Subroto Mitro
Published: December 2023

Penelitian ini bertujuan untuk mengidentifikasi sejauh mana program-program deradikalisasi yang telah diterapkan mampu mengurangi tingkat radikalisasi dan ekstremisme di antara narapidana teroris, serta untuk mengevaluasi rencana pemberian bekal bagi mereka untuk kembali ke masyarakat setelah menjalani hukuman. Metode penelitian yang digunakan adalah kualitatif. Hasil penelitian in mengungkapkan adanya berbagai tingkat keberhasilan dalam program deradikalisasi yang diterapkan di berbagai lembaga pemasyarakatan di Indonesia. Sebagian besar narapidana teroris yang mengikuti program ini mengalami penurunan tingkat radikalisasi dan ekstremisme, dan sebagian besar dari mereka menunjukkan kemajuan dalam pemahaman ideologi yang lebih moderat. Namun, masih terdapat tantangan dalam hal reintegrasi sosial, di mana narapidana teroris seringkali menghadapi stigmatisasi dari masyarakat, sehingga menyulitkan mereka untuk menjalani hidup yang normal setelah bebas. Selain itu, penelitian ini juga menyoroti perlunya kerja sama yang lebih erat antara lembaga pemasyarakatan, pemerintah, LSM, dan masyarakat dalam upaya pencegahan rekrutmen terorisme di dalam penjara.
FORMING RELIGIOUS BEHAVIOR OF GENERATION Z : HOW THE CONTRIBUTION OF HEREDITY
Authors: Dillah Ibnu Ubay , Latipah Eva , Nasar Nasril
Published: December 2023

Generation Z was born in 1997-2012, and now, the population in Indonesia has reached 68 million people. The characteristic of Generation Z is their high dependency on internet access every day. Seeing the phenomenon of Generation Z, which is thick with digital space, how does Generation Z carry out social interactions with the community, how is Generation Z's religious behavior, and whether heredity is a factor in the current phenomenon of Generation Z's religious behavior? The research used is a case study with qualitative research, data collection techniques used as observation, interviews, documentation, and online data tracking. The research subjects were students of the Z generation. The research objects have located in four universities in the Bantul area, the Special Region of Yogyakarta. The results showed that there was an influence of heredity on the behavior of Generation Z using Mendel's theory: 1) Segregation with a ratio of 1:2:1 and 2) Independent Assortment with a ratio of 9:3:3:1. In forming the religious behavior of Generation Z, the principles of religious moderation can be used: 1) Moderate Faith; 2) Moderate Worship; and 3) Moderate Morals.
THE ANALYSIS OF PASSIVE AGGRESSIVE BEHAVIOR ON ISLAMIC ADOLESCENT FROM SINGLE PARENT FAMILIES
Authors: Fauziah Febriella , Netrawati Netrawati , Neviyarni Neviyarni , Nurfarhanah Nurfarhanah
Published: December 2023

This study aims in general to describe the passive-aggressive behavior adolescents can develop from the parenting pattern of single-parent families.  Adolescents who live with a single parent have a risk of delinquency compared to adolescents who are cared for by intact parents. The condition of adolescents who are raised by single parents causes children not to be used to expressing their thoughts and feelings freely. This type of research is quantitative research with a descriptive approach. Data analysis in this study was obtained through a passive-aggressive behavior questionnaire with a Likert scale with a sample of 36 students from single parent families at SMKN 1 Enam Lingkung. The results of the study show that passive-aggressive behavior is in the high category, which means that students have passive-aggressive behavior that needs to be intervened so that students can avoid maladaptive behavior. The school responding to that issue immediately by teachers in schools, especially BK teachers in the implementation of services to reduce passive-aggressive to help students develop more optimally.
RELIGIOUS MODERATION IN THE ACADEMIC ENVIRONMENT: A STUDY OF INTERNALISATION OF RELIGIOUS VALUES AND PATRIOTISM AT UNIVERSITAS LAMBUNG MANGKURAT
Authors: Husin Gt. Muhammad Irhamna , Rusli Rusdi , Arief Muhammad Ihsanul , Ainah Noor
Published: December 2023

We are now facing a tsunami wave of social media development. Anyone and anywhere can access religious information. The impact of this correlates with the vital flow of globalization to all levels of society. The negative influence from the media development side gives a strong impetus for social insecurity. Our integrity as citizens will be at stake because of the appeal of social media. To maintain this, it is essential to strengthen and foster so as not to get out of the path of the nation's ideals. This research discusses how students establish relationships with God and each other in the frame of love for the homeland, surrounded by a plurality of religions, tribes, ethnicities, and cultures, to create an attitude of religious moderation. This type of research is included in field research with quantitative and qualitative approaches. Internalization of spiritual values and love for the homeland in students showed positive results. The results of respondent data show that the strong tendency of religious influence has a positive impact and correlates with love for the homeland. Based on the data, 60% strongly agree, and 28% agree with maintaining relationships with others regardless of anything. This reflects that students' religious understanding has shown an inclusive category, which means they can openly accept differences irrespective of religion, ethnicity, and culture, which is necessary in the Republic of Indonesia.
Kesiapan Implementasi Pengembangan Anak Usia Dini Holistik Integratif (PAUDHI)
Authors: Wahyuni Desvi , Sartika Indah Dwi , Atika Nyimas
Published: December 2023

Penelitian ini juga ditujukan untuk mengetahui kesiapan pemenuhan kebutuhan hak-hak esensial anak usia dini melalui layanan Pengambangan Anak Usia Dini Holistik Integratif (PAUDHI) yang mengintegrasikan layanan pendidikan, kesehatan, pengasuhan, kesejahteraan, dan perlindungan. Dengan menggunakan metode kuantitatif dengan pendekatan survey dan Teknik pengumpulan data berupa observasi, wawancara, dan dokumentasi. Teknik analisis data menggunakan persentase untuk melihat tingkat kesiapan pelaksanaan PAUDHI di desa PL. Hasil penelitian menunjukkan pelaksanaan PAUD di desa PL telah berjalan sebagaimana mestinya walaupun belum. Selain itu, layanan PAUD di desa PL juga telah melaukan kerjasama dengan instansi lain seperti Kesehatan, kepolisisan, dan BKKBN walaupaun belum secara rutin dengan bentuk kegiatan berupa penyuluhan. Oleh karena itu, melalui pengadian kepada maysrakat terkait kesiapan implementasi Pengembangan Anak Usia Dini Holistik Integratif (PAUDHI) dapat dilaksanakan di desa PL.
Solidarity in the Museum: Practices of Representation of Social Problems in Russian Institutions of Contemporary Art
Authors: Petrova Larisa
Published: December 2023

In 2021, 95.5 million people visited Russian museums, and this is sufficient reason to consider the role of museums more than just the collection, storage and demonstration of heritage. Are museums a space of solidarity — do they represent social problems, do they articulate social interests, commonalities and differences of groups? It is especially important to apply this to the institutions of contemporary art in Russia, which over the past 30 years have found their audience and confirmed the reputation of independence, rejection of the canons, and problematization of everyday life. Using the example of two private metropolitan and one well-known state non-capital museum, the author analyzed the content of expositions for 2020-2021 using two methods. The theoretical framework of the study is social constructionism and post-structuralism. The purpose of the article is to characterize the forms and degree of criticality of artistic expression on the example of contemporary art institutions. The author's typology of models for the representation of social problems by museums is used — classical, critical and participatory. Based on empirical data on the expositions of three museums of contemporary art, a conclusion is made about the poorly realized potential of museums of contemporary art as an institution of solidarity — it has clearly not developed. The data demonstrate quantitative differentiation in the representation of critical statements at exhibitions of various institutions — from a third to a half of the exhibitions do not have a critical orientation, do not involve the viewer in the discussion of social problems. The initial nature of the study indicates the need to supplement the methodology with expert assessments, substantiate the measuring model for studying the sphere of culture in general and the museum in particular as an institution of solidarity.
“Doe wat ik schrijf, anders gaat zij eraan…” Contrastieve analyse van anonieme brieven in het Pools en in het Nederlands
Authors: Witczak Anna
Published: December 2023

This article deals with the topic of anonymous extortion letters. Anonymous extortion letters are a challenge for linguists and criminal intelligence services and raise a whole range of questions that ultimately allow a creation of the psycholinguistic portrait of the possible author/-perpetrator. One of these questions concerns the emotional layer of the anonymous letter and the way anonymous authors express their emotions in language. This article describes a specific type of speech genre, which is anonymous extortion letter and analyses, in short, emotions in language. The last part presents the author’s own research, focusing on the characteristics of simulated and falsified extortion letters in the Dutch and Polish languages.
Low waste technology for mine waters treatment using lime and aluminum coagulants
Authors: Trus Inna , Halysh Vita , Tverdokhlib Mariia , Gomelya Mukola
Published: December 2023

In this paper the process of reagent desalination of mineralized mine waters was studied. The peculiarity of mine waters in many regions of Ukraine is that, along with hardness ions, they also contain sulphates in fairly high concentrations. Therefore, the task of desalination of mineralized waters consists in effective removal of sulphates along with softening of the solution. For effective purification of water from sulphates and hardness ions, 5/6 aluminum hydroxychloride (Al2(OH)5Cl) and sodium tetrahydroxoaluminate (Na[Al(OH)4]) were used during liming. A significant increase in efficiency of the treatment process was achieved when the solution was acidified with carbon dioxide after treatment with reagents. The directions of processing of the formed sediments as part of building materials have been determined. Complex processing of the generated waste in the process of water treatment allows creating a low-waste technology for the purification of mineralized water.
The Mousty Formation (Brabant Massif, Belgium): state of the art
Authors: HERBOSCH Alain
Published: December 2023

The Mousty Formation has unique and particularly interesting lithological, mineralogical, sedimentological, metamorphic and tectonic characteristics which have been the subject of much research in connection with the new geological map of Wallonia, but also within the framework of a large amount of academic research, sometimes unpublished. An effort to synthesise and upgrade it in an updated framework seemed necessary. After a history of its definition, mapping and outcrop areas, the following topics are successively addressed in detail and illustrated with diagrams and photos: its lithostratigraphy with the probable discovery of its base near the Court-St-Etienne anticline, its well-constrained biostratigraphy and chronostratigraphy, a new estimate of its minimum thickness, its sedimentology—a subject little addressed until now—, and the resulting depositional sedimentary environment. Its geochemistry, never addressed, is comparable to black shale international standards, except for abnormally high manganese and very low calcium contents; high radon levels in buildings are related to the black slate presence in outcrops. Its mineralogy is rich in manganese-bearing metamorphic minerals, its metamorphism in which we go beyond the strict framework of the formation to deal with the entire southern outcropping rim of the Brabant Massif. Finally, the relationship between the Mousty Formation and the tectonic is discussed, with additional field data, in the context of the innovative and unifying concept of a low-angle extensional detachment called the Asquempont Detachment System. All these observations, some old and some very recent, discussed in the updated framework of the geology of the Caledonian basement of Brabant and in the global stratigraphy and palaeogeography of the lower Palaeozoic, allow us to renew in depth the vision we had of the Mousty Formation and of its place in the Brabant Massif.
What We See as One River is a Convergence of Many: Three Convergence Commitments in University Teaching
Authors: Grain Kari
Published: December 2023

Michael Marker knew we are never just one thing. He often wrote about concepts that gesture toward convergence: To converge as a way of blurring boundaries; To converge as a challenging process of coming-together; to converge educationally in a murky, “alluvial” place of relationality that is only navigable through artistic and storied methodologies (Marker, 2017). Marker steadfastly resisted colonial structures that attempted to tidily delineate knowledge and compartmentalize the unknowable. In this article, I reflect upon Marker’s scholarship through the idea of convergence, and I outline three conceptual spaces of convergence that I have observed in his work. Through analysis of Marker’s body of work, and an attunement to his loving and poetic forms of resistance, I articulate my commitments in my role as a relatively new, non-Indigenous faculty member in his former department at the University of British Columbia. I think of convergence commitments as relational meeting places that can be at once joyful and also tension laden; they are necessary practices that help me to decentre and “muddify” Western ways of knowing that I have been socialized to enact in institutional spaces.
GPR como ferramenta para estudo do controle estrutural do substrato rochoso no desenvolvimento de voçorocas: Gouveia, Espinhaço Meridional, MG, Brasil
Authors: Aranha Paulo Roberto Antunes , Augustin Cristina Helena Ribeiro Rocha , Elmiro Marco Antônio Timbó , Uhlein Alexandre , Joncew Henrique Chaves
Published: December 2023

O voçorocamento constitui, hoje, um problema ambiental grave em vários países, incluindo no Brasil. Esse processo erosivo encontra-se associado à diversas causas, entre elas, o uso e manejo inadequado da terra e às características naturais das vertentes, como o substrato rochoso, que nem sempre são observáveis em levantamentos usuais dos fatores de susceptibilidade à erosão. Neste trabalho, busca-se identificar e analisar a influência do arcabouço geológico e de elementos do relevo com o uso do radar de penetração no solo (GPR) como uma contribuição às abordagens de identificação dos fatores associados ao desenvolvimento das voçorocas. Os resultados do estudo de uma voçoroca em área de domínio dos granitoides na Serra do Espinhaço Meridional, município de Gouveia, MG, Brasil, cujo avanço a montante apresenta uma deflexão da sua orientação original de W-L, para SW-NE, sugerem influência de elementos estruturais no direcionamento da evolução. Também atuam fatores geomorfológicos através da ação do modelado do relevo, cujos processos expõem as rochas subjacentes e acentuam o poder erosivo do escoamento superficial e infiltração da água de chuva, através do aumento da inclinação das encostas.
Analisis Pemetaan Perseptual Dan Preferensi Kunjungan Wisata Religi Kota Banjarmasin Di Masa Pandemi Covid-19
Authors: Hakim Ahmad Firman , Taharuddin Taharuddin
Published: December 2023

Analysis of Perceptual Mapping and References to Religious Tourism Visits in Banjarmasin City during the Covid19 Pandemic (Study on Tourists in Banjarmasin City). Supervised by Taharuddin. This study aims to identify and explain perceptual mapping, visit preferences, predictions of destination religious destinations in Banjarmasin City with perceptual mapping analysis and tourist visit preferences. This research is quantitative research using SPSS for Windows version 26 with Multidimensional scaling analysis method. The sample in this study used the Matchin & Campbell formula with a sample of 150 respondents. The analytical tools used are descriptive analysis, perceptual mapping analysis and thrustone case analysis. Based on the results of the analysis carried out, the results show that the destinations of the Sabilal Muhtadin Grand Mosque, Jami Mosque, and Habib Basirih Tomb which will be crowded Keywords: Perceptual Mapping, Visit Reference, Tourism and Religion
Pengaruh Budaya Organisasi Dan Lingkungan Kerja Dengan Motivasi Sebagai Variabel Intervening Terhadap Kinerja Karyawan (Studi pada Teller Bank Kalsel Cabang Utama Banjarmasin)
Authors: Isliana Noor , Ghalib Saladin
Published: December 2023

This study aims to examine the effect of Organizational Culture and Work Environment with Motivation as an Intervening Variable on Teller Employee Performance at Bank Kalsel Main Branch Banjarmasin. The approach used in this research is quantitative, with the type of causality associative research. The sampling method used nonprobability sampling with saturated sampling method on 32 employees of Teller Bank Kalsel Main Branch Banjarmasin. The google form questionnaire was distributed via Whatsapp to each respondent. Data analysis using SmartPLS softwareThe results showed that Organizational Culture had an insignificant effect on the Performance of Teller Employees of Bank Kalsel Main Branch Banjarmasin, Work Environment had a significant effect on Employee Performance of Teller Employees of Bank Kalsel Main Branch of Banjarmasin, Organizational Culture had a significant influence on Motivation of Teller Employees of Bank Kalsel Main Branch Banjarmasin, The work environment has a significant influence on the motivation of teller employees at Bank Kalsel Main Branch Banjarmasin and motivation has an insignificant effect on the performance of teller employees at Bank Kalsel Main Branch Banjarmasin. While indirectly Organizational Culture has an insignificant effect on Employee Performance mediated by motivation at Bank Kalsel Main Branch Banjarmasin and Work Environment has an insignificant effect on Employee Performance mediated by motivation at Bank Kalsel Main Branch Banjarmasin Keywords: Organizational Culture, Work Environment, Motivation, Employee Performance
Pengaruh Budaya Organisasi, Motivasi Kerja Dan Gaya Kepemimpinan Transformasional Terhadap Kinerja Karyawan Melalui Kepuasan Kerja Karyawan (Studi Pada PT. Harmoni Panca Utama Site MGA Murung Raya Kalimantan Tengah)
Authors: Hasbuloh Ach Zufri , Taharudin Taharudin
Published: December 2023

This study aims to examine and determine the effect of organizational culture, work motivation and transformational leadership style on employee performance through employee job satisfaction. This study used a quantitative approach with the number of samples used for this study were 279 samples who were employees at PT. Harmoni Panca Utama site MGA in Murung Raya, Central Kalimantan. The research data was processed using the SmartPLS 3.2.9 analysis tool and the research method in this study used Structural Equation Modeling (SEM). The results of this study indicate that organizational culture, work motivation and transformational leadership style have a positive and significant effect on employee performance at PT. Harmoni Panca Utama site MGA. The results also show that employee job satisfaction has an indirect effect in mediating the impact on the relationship between organizational culture, work motivation and transformational leadership style on employee performance at PT. Harmoni Panca Utama site MGA. Keywords: Organizational Culture, Work Motivation, Transformational Leadership, Employee Performance, Job Satisfaction
Implementasi Kebijakan Gerakan Stop Buang Air Besar Sembarangan Di Desa Pasar Senin, Desa Kandang Halang, Dan Desa Rantawan Kecamatan Amuntai Tengah Kabupaten Hulu Sungai Utara (Studi Kasus Peraturan Daerah Kabupaten Hulu Sungai Utara Nomor 04 Tahun 2016 Tentang Gerakan Stop Buang Air Besar Sembarangan)
Authors: Budiman Arif , Pratama Deva Angga
Published: December 2023

The problems that exist are that there are still residents who carry out open defecation activities, there are several latrines along the river, and there is no clear socialization from the government. So the government made North Hulu Sungai Regency Regional Regulation Number 04 of 2016 concerning the Movement to Stop Open Defecation. The aim of this research is to determine the implementation of the stop open defecation movement policy and to find out what factors influence the implementation of the stop open defecation movement policy. The research used is a qualitative approach with a descriptive type. Data collection techniques use interviews, observation and documentation. The data source was taken from 11 informants using purposive sampling. Data analysis techniques using data reduction, data presentation, and drawing conclusions. The results of this research show that the implementation of the Stop Open Defecation Movement Policy in Pasar Rabu Village, Kandang Halang Village, and Rantawan Village, Amuntai Tengah District, North Hulu Sungai Regency is quite good. First, interests that influence clear indicators of policy targets have not been implemented, and the level of policy satisfaction has not been implemented well. Second, the types of benefits with policy benefit indicators have not been implemented, and the continuity and continuity of benefits have not been implemented. Third, the degree of change with indicators of the degree to be achieved is sufficiently implemented. Fourth, the position of policy makers with indicators of accountability for policy implementers has been implemented. Fifth, program implementers with indicators of competence and quality of policy implementers are quite well implemented, and clear communication and coordination of program implementers have been implemented. Sixth, the resources involved with adequate human resource indicators have not been implemented properly, and the supporting facilities and infrastructure have not been implemented. Keywords: Policy on the Movement to Stop Open Defecation, Regional Regulations, Villages
Method of matched sections in application to thin-walled and Mindlin rectangular plates
Authors: Danylenko Kirill , Orynyak Igor
Published: December 2023

The paper elaborates the principally new variant of finite element method in application to plate problem. It differs from classical FEM approach by, at least, three points. First, it uses the strong differential formulation rather than the weak one and suppose the approximate analytical solution of all differential equations. Second, it explicitly uses all geometrical and physical parameters in the procedure of solution, rather than some chosen ones, for example, displacement and angles of rotation as usually done in FEM formulation. Third, the conjugation between adjacent elements occurs between the adjacent sections rather than in polygon vertexes. These conditions require the continuity of displacements, angles, moments and forces. Each side of rectangular elements is characterized by 6 main parameters, so, at whole there are 24 parameters for each rectangular element. The right and upper sides’ parameters are considered as output ones, and they are related with lower and left sides ones by matrix equations, which allows to apply transfer matrix method for the compilation of the resulting system of equations for the whole plate. The numerical examples for the thin-walled and Mindlin plates show the high efficiency and accuracy of the method.
O PROGRAMA RESIDÊNCIA PEDAGÓGICA E AS AULAS DE QUÍMICA NA PANDEMIA
Authors: Souza Renato Fernandes de , Pires Diego Arantes Teixeira
Published: December 2023

A Residência Pedagógica é um programa ofertado pela CAPES, que faz parte de uma política pública que visa o incentivo e a valorização na formação de professores. O programa apresenta o objetivo de aperfeiçoar a formação dos discentes dos cursos de licenciatura, exercitando ativamente a relação entre a teoria e prática profissional docente. Por meio de uma metodologia qualitativa de pesquisa, do tipo estudo de caso, aplicou-se um questionário para os professores preceptores participantes da Residência Pedagógica, a fim de saber como o Estado e as escolas ofereceram treinamentos e suportes para as aulas online, durante a pandemia, bem como investigar como ocorreram as aulas remotas de Química. Notou-se que o Estado e as escolas não ofereceram suporte e treinamento adequado aos professores e alunos durante as aulas remotas, e as aulas de Química tinham poucas variações metodológicas. E nesse sentido, residentes do curso de Licenciatura em Química propuseram atividades com estratégias de ensino variadas, como experimentos e atividades lúdicas, para serem utilizados durante as aulas online, auxiliando os professores no complexo processo de regência durante a pandemia.
CONTRIBUIÇÕES DO PROGRAMA RESIDÊNCIA PEDAGÓGICA VIVENCIADA POR MEIO DA APLICAÇÃO DO KAHOOT EM UMA TURMA DE 1° ANO DO ENSINO MÉDIO NA DISCIPLINA DE QUÍMICA
Authors: Souza Kauany Andressa de Oliveira , Souza Gahelyka Aghta Pantano , Haraguchi Shirani Kaori
Published: December 2023

O objetivo deste trabalho é relatar a importância da inserção do estudante de licenciatura na educação básica em plena formação inicial, retratado por meio da experiência docente com alunos do primeiro ano do ensino médio. Essa vivência foi retratada nas ações do primeiro módulo do programa Residência Pedagógica (RP) do subprojeto de Química na Universidade Federal do Acre (UFAC). Participaram das atividades relatadas alunos do primeiro ano do ensino médio, do Colégio de Aplicação do Acre (CAP). Utilizando-se da aplicação de um Quiz como instrumento de avaliação da eficácia das aulas sobre o ensino dos conteúdos de “Ligações Químicas, Geometria Molecular, Polaridade das Moléculas e Forças Intermoleculares”. De modo geral, os estudantes mostraram grande envolvimento durante a aplicação do Quiz buscando sanar suas dúvidas, sendo notório que é preciso diversificar os métodos durante as aulas. Tais fatos fomentam a importância do licenciando participar de atividades que os insiram no ambiente escolar para que os mesmos percebam que em uma sala de aula é necessário o uso de diversos materiais.
CONTRIBUIÇÕES DO PIBID NO INÍCIO DA CARREIRA DE PROFESSORES DE MATEMÁTICA
Authors: Silva Fabiane Andrade da , Ribeiro Emerson da Silva
Published: December 2023

O presente estudo é fruto de uma pesquisa que teve como enfoque as temáticas início da carreira docente e formação inicial de professores, esta última considerando o Programa Institucional de Bolsas de Iniciação à Docência (PIBID) como uma política governamental de formação docente e de valorização do magistério. A pesquisa teve como questão norteadora: “Quais as contribuições do PIBID no início da carreira docente de professores que ensinam Matemática?” e, como objetivo, analisar as contribuições do PIBID no início da carreira docente a partir da perspectiva de ex-bolsistas do subprojeto de Matemática da Universidade Federal de Rondônia (UNIR) que atuam como professores iniciantes de Matemática. Metodologicamente, a pesquisa se configurou como uma investigação de abordagem qualitativa, em que dois questionários foram utilizados como instrumentos de produção de dados. Os sujeitos da pesquisa foram três professores de Matemática com até cinco anos de ingresso e atuação na carreira docente, e que foram bolsistas do subprojeto PIBID de Matemática do Campus da UNIR de Ji-Paraná. Com base nos dados de pesquisa, concluiu-se que o PIBID proporcionou a troca de experiências entre o universo acadêmico e escolar, propiciando o conhecimento e um melhor entendimento do ambiente de sala de aula, de forma a articular as teorias discutidas no âmbito da licenciatura e as práticas docentes de Matemática das escolas de Educação Básica.
CICLO DE MOMENTOS FORMATIVOS NA FORMAÇÃO INICIAL DE PROFESSORES DE MATEMÁTICA NO ÂMBITO DO PIBID NA UFT E UFNT
Authors: Fonseca Adriano , Costa Dailson Evangelista , Klein Janete Aparecida , Moraes Mônica Suelen Ferreira de
Published: December 2023

Este artigo apresenta reflexões sobre o processo de inserção de licenciandos em Matemática no contexto escolar. A questão de pesquisa é: Que sentidos/significados foram produzidos pelos licenciandos em relação às ações realizadas durante sua participação no PIBID? Tem como objetivo apresentar reflexões sobre os sentidos/significados que os pibidianos produziram em relação aos momentos formativos do subprojeto do PIBID - Licenciaturas em Matemática - da Universidade Federal do Tocantins (UFT) e Universidade Federal do Norte do Tocantins (UFNT). Trata-se de uma pesquisa de abordagem qualitativa do tipo pesquisa de campo. Utilizamos um questionário com seis perguntas abertas como instrumento de produção de informações (coleta de dados) e este foi respondido por 34 pibidianos por meio da ferramenta digital google form. Estabelecemos o seguinte eixo analítico: Ciclo de momentos formativos na formação inicial de professores de Matemática no âmbito do PIBID. Para interpretar as informações, realizamos uma análise descritiva, interpretativa e analítica das respostas do questionário. Os resultados apontam que a inserção dos pibidianos no contexto escolar foi conduzida de maneira sistemática e reflexiva, como processo de integração, de profissional e pessoal, contribuindo para a constituição de uma identidade profissional própria da docência na educação básica.
Establishment of a Novel Cancer-Specific Anti-HER2 Monoclonal Antibody H2Mab-250/H2CasMab-2 for Breast Cancers
Authors: Kaneko Mika K , Suzuki Hiroyuki , Ohishi Tomokazu , Tanaka Tomohiro , Kato Yukinari
Published: December 2023

Overexpression of human epidermal growth factor receptor 2 (HER2) in breast and gastric cancers is an important target for monoclonal antibody (mAb) therapy. All therapeutic mAbs, including anti-HER2 mAbs, exhibit adverse effects probably due to the recognition of antigens expressed in normal cells. Therefore, tumor-selective or specific mAbs can be beneficial in reducing the adverse effects. In this study, we established a novel cancer-specific anti-HER2 antibody, named H2Mab-250/H2CasMab-2 (IgG1, kappa). H2Mab-250 reacted with HER2-positive breast cancer BT-474 and SK-BR-3 cells. Importantly, H2Mab-250 did not react with non-transformed normal epithelial cells (HaCaT and MCF 10A) and immortalized normal epithelial cells in flow cytometry. In contrast, most anti-HER2 mAbs including H2Mab-119 (IgG1, kappa) reacted with both cancer and normal epithelial cells. Furthermore, a core-fucose deleted IgG2a-type H2Mab-250 (H2Mab-250-mG2a-f) could trigger the antibody-dependent cellular cytotoxicity activity to BT-474, but not to HaCaT cells. Furthermore, H2Mab-250-mG2a-f exhibited an in vivo antitumor effect against BT-474 xenograft. Immunohistochemical analysis demonstrated that H2Mab-250 possesses much higher reactivity to the HER2-positive breast cancer tissues compared to H2Mab-119, and did not react with normal tissues, including heart, breast, stomach, lung, colon, kidney, and esophagus. The epitope mapping demonstrated that the Trp614 of HER2 domain IV mainly contributes to the recognition by H2Mab-250. H2Mab-250 could contribute to the development of chimeric antigen receptor-T or antibody-drug conjugates without adverse effects for breast cancer therapy.
Evaluation of Drought Tolerance in USDA Tomato Germplasm at Seedling Stage
Authors: Chiwina Kenani , Bhattarai Gehendra , Xiong Haizheng , Joshi Neelendra K. , Dickson Ryan , Phiri Theresa , Alatawi Ibtisam , Chen Ylin , Stansell Zachary J , Ling Kai-Shu , SHI Ainong
Published: December 2023

Drought, a crucial abiotic stressor, markedly reduces the growth and yield of tomato crops (Solanum lycopersicum L.). Consequently, adopting drought-resistant cultivars and implementing breeding programs to enhance drought tolerance have emerged as enduring solutions to alleviate the adverse effects of drought in various tomato cultivation regions. In this study, 68 tomato accessions from the United States Department of Agriculture (USDA) were assessed in a controlled greenhouse experiment, encompassing both water deficit treatment and a control group subjected to standard watering conditions. The experiment was arranged in a randomized complete block design with three replications. The results of this study pinpointed four accessions PI 365956, PI 584456, PI 390510, and PI 370091, as drought-tolerant accessions. Additionally, high broad-sense heritability was revealed for leaf wilting, leaf rolling, and SPAD chlorophyll content (total leaf chlorophyll). Furthermore, positive correlations were found among parameters associated with leaf wilting, leaf rolling, and SPAD chlorophyll content. The findings of this study provide valuable insights relevant to tomato breeding initiatives, particularly those aimed at fortifying drought tolerance within the elite cultivars of this essential crop.
A Review on the Biorefinery Approach and Marketing Strategy of Leafy Biomass
Authors: Yeasmen Nushrat , Bhuiyan Md. Hafizur Rahman , Orsat Valerie
Published: December 2023

In terms of sustainability, there is a pressing need to evaluate agricultural and forestry leafy biomass that has no current economic value or may pose a threat to the environment. In this aspect, leafy biomass, which represents around 5% of the total tree, can be used for purposes that would be more profitable and ecofriendly. To this end, biorefinery of leafy biomass in the way of extracting valuable health compounds such as phenolics would ensure a valuable societal health ingredient besides alleviating waste disposal problem. However, during the biorefinery process, the primary challenges start with ensuring the feedstock to produce phenol rich leaves extract followed by their isolation and commercialization of this leaves extract. This current review aims to detail the types of biomasses, biorefinery approach of leafy biomass towards the phenolic extraction, leaves commercialization followed by the marketing strategy of the application of phenol rich leaves extract. The outcome of this overview will serve researchers and relevant industries in understanding the process for feedstock collection and the suitable sectors to apply leafy biomass derived healthy compounds.
Recent Treatment Strategies for Acute Pancreatitis
Authors: Song Yong Cook , Lee Sang Hoon
Published: December 2023

Acute pancreatitis (AP) is a leading gastrointestinal disease that cause hospitalization. Initial management in the first 72 h after the diagnosis of AP is pivotal, which can influence the clinical outcomes of the disease. Initial management, including fluid resuscitation, pain control, nutritional support, antibiotic use, and endoscopic retrograde cholangiopancreatography (ERCP) in gallstone pancreatitis, plays a fundamental role in AP treatment. Recent updates for fluid resuscitation, including treatment goals, the type, rate, volume, and duration, have triggered a paradigm shift from aggressive hydration with normal saline to goal-directed and non-aggressive hydration with lactated Ringer’s solution. Evidence of the clinical benefit of early enteral feeding is becoming definitive. Routine use of prophylactic antibiotics is generally limited, and the procalcitonin based algorithm of antibiotic use has recently been investigated to distinguish between inflammation and infection in patients with AP. Although urgent ERCP (within 24 h) should be performed for patients with gallstone pancreatitis and cholangitis, urgent ERCP is not indicated in patients without cholangitis. Furthermore, convalescent treatment, including cholecystectomy in gallstone pancreatitis and alcohol intervention in alcoholic pancreatitis, is also important for improving the prognosis and prevent recurrence in patients with AP. This review focuses on recent updates on the initial and convalescent management strategies for AP.
Synergistic Impact of Organic Acids on Rabbits’ Digestive Physiological Processes and Health
Authors: Vilienė Vilma , Nutautaitė Monika , Šašytė Vilma , Bliznikas Saulius , Pockevičius Alius , Slausgalvis Virginijus , Gugołek Andrzej , Strychalski Janusz , Juśkiewicz Jerzy , Matusevičius Paulius , Racevičiūtė-Stupelienė Asta
Published: December 2023

Understanding the implications of organic acids in animal diets on physiological markers is critical for developing viable strategies for improving overall health and performance. The aim of this study was to evaluate the influence of dietary organic acids inclusion on rabbits’ growth performance and physiological status by determining blood and intestine development indicators. Forty weaned rabbits aged 28-d randomly assigned into 2 groups and fed with standard compound diet (SCD) and SCD + 0.2% organic acids mixture (butyric, propionic, sorbic; OAM). Growth performance was evaluated between 28-77 d of age, physiological status at 77 d of age. OAM’s rabbits final body weight, ADG, DFI, growth rate indicators were higher, but FCR lower compared to SCD (P < 0.05). OAM increased total protein and albumin levels in blood plasma; reduced pH, increased DM, achieved greater viscosity in caecum’s content (P < 0.05). Compared to SCD better gut development observed in OAM, as total intestinal weight was significantly higher (P < 0.05). Acetic and propionic acids concentrations were increased, but butyric reduced in OAM caecum’s content (P < 0.05). OAM had significant effect on the most caecum histomorphometric parameters: increased villus height, crypt depth and their ratio (P < 0.05). According to our results OAM can improve rabbits’ growth performance, nutrient intake, and feed digestibility by significantly improving physiological status.
Recent Progress and Challenges of Metal-Organic Framework-Based Membranes for Gas Separation
Authors: Tanaka Shunsuke , Fuku Kojiro , Ikenaga Naoki , Sharaf Maha , Nakagawa Keizo
Published: December 2023

Metal-organic frameworks (MOFs) represent the largest class of materials among the crystalline porous materials ever developed and have attracted attention as core materials for separation technology. Their extremely uniform pore aperture and nearly unlimited structural and chemical characteristics have attracted great interest and promise in applying MOFs to adsorptive and membrane–based separations. This paper reviews the recent research and development of MOF membranes for gas separation. Strategies for polycrystalline membranes and mixed matrix membranes are discussed, with a focus on separation systems involving hydrocarbon separation and CO2 capture. Challenges and opportunities for the industrial deployment of MOF membranes are also be discussed, providing guidance for the design and fabrication of future high-performance membranes. The contributions of the underlying mechanism to separation performances, and the adopted strategies and membrane processing technologies for breaking the selectivity/permeability trade–off are discussed.
Longitudinal NMR-Based Metabolomics Study Reveals How Hospitalized COVID-19 Patients Recover: Evidence of Dyslipidemia and Energy Metabolism Dysregulation
Authors: Ansone Laura , Rovīte Vita , Brīvība Monta , Jagare Lauma , Pelcmane Līva , Borisova Daniella , Thews Anne , Leiminger Roland , Kloviņš Jānis
Published: December 2023

Long Covid or post-acute sequelae of SARS-CoV-2 infection (PASC) can manifest as long-term symptoms in multiple organ systems, including respiratory, cardiovascular, neurological, and metabolic systems. In patients with severe COVID-19, immune dysregulation is significant, and the relationship between metabolic regulation and immune response is of great interest in determining the pathophysiological mechanisms. We aimed to characterize the metabolomic footprint for recovering severe COVID-19 patients in three consecutive time points and compare metabolite levels to controls. Our findings add proof of dysregulated amino acid metabolism in the acute phase, and dyslipidemia, glycoprotein level alterations, and energy metabolism disturbances in severe COVID-19 patients 3-4 months post hospitalization.
MMdb: Genomic Resource for the Improvement of the Family Musaceae
Authors: Biswas Manosh Kumar , Biswas Dhiman , Sheng Ou , Yi Ganjun , Deng Guiming
Published: December 2023

The availability of genomic sequences and bioinformatics tools has facilitated genome-scale marker discovery. Microsatellite (SSR), Single Nucleotide Polymorphism (SNP), and Intron Length Polymorphism (ILP) markers are widely used in crop improvement and population genetics studies, developed using extensive bioinformatics pipelines. Here we introduce the Musa Molecular Marker Database (MMdb) as a valuable online resource for enhancing Musa species. It is a diverse array of molecular markers resources, including SSR, SNP, and ILP. This database contains 2115474 SSR, 63588 SNP, and 91547 ILP markers developed from twelve Musa species and three of its relative species. This online resource is freely accessible, following a 'three-tier architecture,' and organizes marker information in MySQL tables. It has user-friendly interface, that is written in JavaScript, PHP, and HTML code. Users can employ flexible search parameters, including marker location in the chromosome, transferability, polymorphism, and functional annotation, among others. This unique feature sets MMdb apart from existing marker databases, offering a novel approach that caters to the needs of the Musa research community. Despite being an in silico method, searching for markers based on various attributes holds promise for Musa research. These markers serve various purposes, including germplasm characterization, gene discovery, population structure analysis, and QTL mapping.
Insights into an Autologous Dendritic Cells Vaccine for Glioblastoma: First Step Results from a Phase II Study (CombiG-Vax)
Authors: Ridolfi Laura , Gurrieri Lorena , Riva Nada , Bulgarelli Jenny , De Rosa Francesco , Guidoboni Massimo , Fausti Valentina , Ranallo Nicoletta , Calpona Sebastiano , Tazzari Marcella , Petrini Massimiliano , Granato Anna Maria , Pancisi Elena , Foca Flavia , Dall'Agata Monia , Bondi Isabella , Amadori Elena , Cortesi Pietro , Gamboni Alessandro , Polselli Antonio , Pasini Giuseppe , Bartolini Daniela , Maimone Giuseppe , Tosatto Luigino
Published: December 2023

Background
Glioblastoma (GBM) is a poor prognosis malignant grade 4 glioma. After surgical resection, standard therapy consists of concurrent radiotherapy (RT) and temozolomide (TMZ) followed by TMZ alone. The DC vaccination increased the amount of intratumoral-activated cytotoxic T lymphocytes and decreased the number of FoxP3-positive regulatory T cells. Based on these da-ta, we have developed a phase II protocol with the DC vaccine concomitant to standard RT-CT in patients undergoing surgery for GBM.
Methods
This is a single-arm, monocentric, phase II trial evaluating progression-free survival (PFS) and the safety of a DC vaccination integrated with standard therapy in resected GBM patients. The vaccine administration begins at the end of the RT-CT (Induction Phase) and is subsequently al-ternated with TMZ cycles (Maintenance Phase). The primary endpoints are PFS and safety. Among the secondary endpoints, are the in vitro and in vivo Immune response evaluations.
Results
By December 2022 , nine patients had been enrolled in the first step. Two patients progressed within three months after leukapheresis and none had experienced DC vaccine-related G3-4 tox-icity. Five patients had a positive DTH test against KLH. By June 2023. The median OS from leu-kapheresis was 23.1 months and 24.7 from surgery.
Conclusions
This combination therapy is well-tolerated, and we have achieved the two endpoints required for the first step. Therefore, the study will proceed to enroll the remaining 19 patients.
Evaluation of Treated Wood Fibres Performance in Cement Mortars
Authors: Kampragkou Petrini , Kamperidou Vasiliki , Stefanidou Maria
Published: December 2023

The biofibres wide application as mortars enhancement have been so far restricted by factors related to their chemical composition and hygroscopic nature. Their hydrophilic behavior increases the water demand of mortar-mixtures and diminishes their adhesion to the matrix, while further moisture-related fibre degradation issues may arise. Additionally, the natural fibres seem to be susceptible to degradation caused during the exposure to alkaline environments conditions, such as those of cement mortars, restricting their utilization in construction industry. Therefore, the current study focusses on the potential of fibre modification through treatments that would permanently alter their structure and chemical composition in the whole mass or surface towards their performance improvement. In this study, mild hydrothermally treated wood fibres of black pine and beech species were prepared and incorporated in cement mortars to assess their performance, applying the proportion of 1.5% v/v in the mortar. The mortars workability (at fresh state), physical, hygroscopic, chemical, thermal, and mechanical characteristics at the age of 28, 90 and 365 days and weathering performance by subjecting them at different artificial ageing environments (freeze-thaw cycles or outdoor exposure) were examined. The results indicated the beneficial role of the treated fibres in the dimensional stability, flexural strength, thermal insulation properties and capillary absorption of the mortar specimens, especially during ageing process, with the black pine fibres to reveal the highest improvement. The hydrothermally treated wood fibres seem to ensure the integrity maintenance of cement mortars under all ageing conditions, proving that the specific bio-additives could provide low-cost and eco-friendly mortar enhancement pathways.
Development of Novel Bioluminescent Biosensors Monitoring Conformation and Activity of Merlin Tumor Suppressor
Authors: Pipchuk Alex , Kelly Tynan , Carew Madeleine , Nicol Christopher , Yang And Xiaolong
Published: December 2023

Solid tumors universally possess the ability to evade contact inhibition of proliferation (CIP), a mechanism halting cell proliferation when cell-cell contacts occur. Merlin, an ERM-like protein, crucially regulates CIP and is frequently deactivated in various cancers, indicating its signifi-cance as a tumor suppressor in cancer biology. Despite extensive investigations into Merlin's role in cancer, its lack of intrinsic catalytic activity and frequent conformation changes has made it notoriously challenging to study. To address this challenge, we harnessed innovative luciferase technologies to create and validate a split-luciferase biosensor system. This system enables precise quantification of Merlin's conformation and activity both in vitro and within living cells. This biosensor significantly enhances the study of Merlin's molecular functions, serving as a potent tool to explore its contributions to CIP and tumorigenesis.