bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFECTIVENESS OF DIFFERENT FORMS AND LEVELS OF SELENIUM FOR PIGLETS RAISING
Authors:   Federal Scientific Center – All-Russian Research Institute of Animal Breeding, Chabaev M.G. , Nekrasov R.V. ,   Federal Scientific Center – All-Russian Research Institute of Animal Breeding, Klementyev M.I. ,   Federal Scientific Center – All-Russian Research Institute of Animal Breeding, Tzis Ye.Yu. ,   Federal Scientific Center – All-Russian Research Institute of Animal Breeding
Published: February 2025

Experimental studies on determination the effectiveness of B-Traxim Selenium were
carried out on piglets of large white breed, arranged in three groups of 30 head each on the
principle of analogues; duration of the experiment: 90 days. For 28 days, suckling sows received compound feed SK-2 according to the feeding scheme adopted at the enterprise. In the
suckling phase the young animals were fed with compound feed SK-3; in the post-weaning
period (29-60 days) and in growth phase (60-90 days) they were fed with compound feed SK3 and SK-4, respectively. Piglets from the experimental groups received 0.15 and 0.20 mg of
B-Traxim Selenium per 1 kg of compound feed. Piglets of the control group were fed with
compound feed SK-3 and SK-4 including of 0.3 mg of inorganic selenium per 1 kg of compound feed. The use of different levels of B-Traxim Selenium per 1 kg of compound feed
stimulated the intensity of live weight gain of piglets in the weaning and growth phase by 3.1
and 2.7% and 6.5 and 3.9%, respectively as compared to the control, and in the age of 60-90
days it amounted to 7.0 and 3.5%. Different levels of B-Traxim Selenium, being added to the
compound feed prestart, stimulated the digestibility of all nutrients compared to the control
group. In the piglets of the experimental groups, the content of red blood cells, leukocytes and hemoglobin increased by 3.9 and 2.9; 7.5 and 6.0; 3.6 and 3.2%, respectively as compared to the control. We also found an apparent tendency to increase in the level of total
protein in the serum of the experimental groups by 3.9 and 3.8% as compared to the control.
Rising young animals that received different levels of B-Traxim Selenium had high bactericidal, lysozyme and phagocytic activity. The greatest economic effect was obtained in the 2nd
experimental group of piglets, that received 0.15 mg of B-Traxim Selenium per 1 kg of feed,
and amounted to 330 rubles per one head.
VARIABILITY OF THE FATTY ACID COMPOSITION OF OIL IN THE SEEDS OF SOMACLONAL SOYBEAN LINES
Authors:   All-Russian Research Institute of Soybean, Kodirova G.A , Kubankova G.V. ,   All-Russian Scientific Research Institute of Soybean, Efremova O.S. ,   All-Russian Research Institute of Plant Industry, Fisenko P.V. ,   Federal Research Center for Agrobiotechnologies of the Far East named after A.K. Chaika
Published: February 2025

The article presents the results of biochemical studies of the fatty acid composition of soybean
seed material obtained by the method of somaclonal variability in invitro culture using cadmium ions
in nutrient media. It was found that under the influence of cadmium ions as a mutagenic agent in
the studied somaclone seeds, there is an increase in the content of oil, oleic and linoleic acids, as well
as a decrease in linolenic. R1591 line reliably exceeded the original variety in oil content and in the
complex of unsaturated fatty acids (oleic, linoleic, linolenic). Three lines that have significant advantages in a number of characteristics have been identified: fat content (R1609), linolenic acid
(R1605), linoleic and linolenic acids (R1584). As a result of analysis, changes in the ratio of saturated
and unsaturated fatty acids have also been established: C18:2 /C18:1; C18:3 /C18:2, indicating stable and
permanent (to a greater or lesser extent) differences between somaclonal lines and their original
forms.
RESULTS OF COMPLEX ASSESSMENT OF COLLECTABLE VARIETIES OF POTATO IN THE CLIMATE OF KAMCHATSKY KRAI
Authors:   Kamchatsky Research Institute of Agriculture, Sherstyukova T.P. , Ivashchenko A.D. ,   Kamchatsky Research Institute of Agriculture
Published: February 2025

The article presents the results of the four-year study of the collection of potato varieties under
the conditions of the Kamchatsky Krai. The research was carried out during years 2015-2018 at the
Kamchatka Research Institute of Agriculture Laboratory of Biotechnology of Field Crops and Potato
Breeding. The object of research: 115 varieties of domestic and foreign selection; Fresco variety as
a standard. The following varieties had a high sustainable yield that was higher than the Fresco
standard (22.0 t / ha): Anosta, Astilla, Impala, Latona, Paul Wagner, Raya, Solnyshko, Sapho, Fiesta, Chaika. High marketability of tubers belonged to varieties - Alvar, Varmas, Vulcan, Velican,
Geyser, Impala, Lazar, Latona, Monaliza, Petersburg, Pushkinetz, Sapho, Evolution, Yugra. High
content of dry matter (19.1-21.8%) and starch (13.0-16.1%) in potato tubers were found in the varieties Adretta, Alyi Mestny, Agatha, Alvara, Vasilyok, Visa, Vulcan, Velikan, Geyser, Dalvas, Doonun, Karina, Lazar, Pamyaty Rogacheva, Proventa, Pushkinetz, Paul Wagner, Raya, Chaika, Ugra.
The highest content of vitamin C in tubers (5.7-18.2 mg%) were found in the varieties Anosta, Vulcan, Kamensky, Ladozhsky, Pushkinetz, Pamyaty Rogacheva, Raya, Monaliza. 31% of the studied
samples had high taste qualities (4.5 -5.0 points). According to the findings of investigations a number of the varieties with resistance to viral diseases were identified: Alyi Mestny, Apis, Astilla, Alyona,
Bridge, Veline, Vasilyok, Velikan, Vulcan, Geyser, Doo-Nun, Dalvas, Elizaveta, Kamchatka, Koryaksky -1, Latona, Lazar, Otrada, Olsky, Resurs, Rodriga, Raya, Udacha, Fiesta, Ugra, Yantar.
Thus, on the Kamchatsky Krai, varieties characterized by high adaptive productive potential with the
best biochemical indices of tubers and disease resistance were singled out: Anosta, Alyi Mestny, Alyona, Apis, Astilla, Geyser, Vulcan, Zhukovsky early, Latona, Raya, Paul Wagner, Pushkinetz, Pamyaty Rogacheva, Solnyshko, Sapho, Fiesta, Chaika, Ugra. The varieties of potatoes singled out here
are used in breeding work as a starting material (base line) for creating new varieties.
COMPLEX ASSESSMENT OF POTATO SOURCE MATERIAL (BASE LINE) USING ELECTRONIC DIGITAL ANALYZER "MINI-PAM»
Authors:   All-Russian Research Institute of Soya, Rafalskiy S.V. , Rafalskaya O.M. ,   All-Russian Research Institute of Soya, Melnikova T.V. ,   All-Russian Research Institute of Soya
Published: February 2025

The article presents the results of assessment of potato breeding samples by means of the
"MINI-PAM" analyzer of photosynthetic activity of plants. The maximum values of the quantum
yield of photosynthesis (over 0,750 units) were found in the varieties Vitessa, Jubilyar, Rosamunda,
Krasavitza Bryanshchiny, Natasha, Rosara, which were related to the early maturation group. The
varieties of the middle-early ripeness group: Krasavchik, Kolyanis, Kamchatka, Emelya, Vulkan had
the quantum yield of plant photosynthesis ranging from 0.760 to 0.786 units. The middle-late varieties
Zolsky and Smak showed values 0.749 and 0.758 units (at that, maximum of this value in plants
amounts to 0.820 units). It was found that potato varieties belonging to the first two groups of ripeness
with the coefficients of variation (V) 12.94% and 11.75%, respectively, and the range of variation of
0.292 units and 0.230 units, had a significant, close direct correlation between tuberous productivity
of the studied varieties and the quantum yield of photosynthesis. The highest yield of tubers per 1 ha
in the early ripening group was produced by the varieties Natasha (23.6 t), Rosara, Krasavitza Bryanshchiny (22.8 t), Vitessa (22.5 t), Jubilyar (22.4 t), Rosamund (22.2 t). In the middle-early group,
the maximum productivity from 21.4 to 24.8 t / ha, was registered in the varieties Vulkan, Kamchatka,
Emelya, Kolyanis, Krasavchik with average variability (V = 11.02%). The highest yield of tubers in
the mid-late ripening group amounted to 21.8 and 28.1 t / ha in the varieties Zolsky and Smak. The
dependence between the varieties productivity, estimated yield of starch per 1 ha and the value of
quantum yield of photosynthesis, which characterizes the activity of the photosynthetic system of
plants, was studied with the help of statistical analysis that determined its (quantum yield) proportion
of influence in the change of value of productive traits. The results of a comprehensive assessment of
potato varieties allow us to identify the most promising genetic sources with increased adaptive production potential.
CONDITIONS AND LABOR COSTS OF MACHINE MAINTENANCE IN THE FIELD
Authors:   Irkutsk State Agrarian University named after A.A. Ezhevsky, Habardin Vasilij N.
Published: February 2025

According to the rules of GOST 20793-2009, machine maintenance (M) is carried out not
only under stationary conditions, but also at the places of their use – in the field. It should be assumed
that the working conditions of the maintenance operator in the field differ from the conditions for
performing these works at a maintenance station, for example, at service center (SC). If this is the
case, then the task of determining the impact of the operator's working conditions on his labor costs
will certainly arise. This article is devoted to solving this problem. In particular, it presents the methodology and results of an experimental study to determine the field conditions and labor costs in the
maintenance of tractors at the agricultural enterprises of the Irkutsk Region. At the same time, it was
found that the integral coefficient of the operator's working conditions in the field varies from 0.06
to 0.92; its average value is 0.60, which is 0.4 (40 %) less than at service centers. Carrying out machine maintenance in the field, provided that a sufficient level of its quality is observed, is accompanied by an increase in labor costs, which depends on the working conditions of the operator. The
findings of the investigations can be taken into account when justifying and selecting methods, as
well as when developing facilities for machine maintenance in agriculture. In General, this study is
aimed at resource saving and improvement of working conditions of machine maintenance.
Community-Based Intervention for Malnutrition in Children Under Five: A Scoping Review
Authors: Amelia Vira , Arief Yuni Sufyanti , Sylvia Dwi Wahyuni
Published: February 2025

Malnutrition remains a significant global challenge, especially in developing countries. This scoping review aimed to identify community-based strategies for malnutrition in children under five. The scoping review conducted herein adhered to the methodologies outlined in conjunction with the guidelines specified in the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) extension for the scoping Reviews checklist. This study used three databases (PubMed, ProQuest, and Scopus) and included studies published between 2014-2024, with the search keywords "Intervention" or "Community-Based Intervention," “Children,” and “Malnutrition.” Results: Out of the 4846 identified articles, 11 studies were selected based on strict eligibility criteria. The results show that education, empowerment, supplementation, screening and monitoring, and other community-based interventions (home visits and meeting groups) contribute to malnutrition. The importance of community-based innovation in overcoming malnutrition in children can improve children's nutritional and health status. Program development includes increasing nutrition education, empowerment, providing adequate supplements, effective screening and monitoring to ensure the sustainability and effectiveness of community-based nutrition interventions.
Development of BRUSLE hologram augmented reality based on Android apps by Engklek ethno-games Learning
Authors: Falah Mochammad Faiz Nur , Rifqy Muhammad Iqbal , Primrose Ailsa Tsabita , Mukti Taufiq Satria
Published: February 2025

Curved Side Spaces (BRSL) in learning need to be presented with learning media to make it easier for students to understand the concept. This research aims to produce learning media based on technology and cultural values. The media in question is (BRUSLE) an Android application that can be accessed via mobile with augmented reality hologram content and integrated traditional Engklek game in the learning process. Development research was conducted using the ADDIE model (Analysis, Design, Development, Implementation, Evaluation). The development was carried out based on a needs analysis at MTs N 2 Malang grade 7 in 2023 Mathematics Subjects on BRSL material. The developed product was carried out content validity by 3 experts (media, mathematics learning, and practitioners / teachers) to continue the feasibility test. The first stage feasibility test was conducted on 29 students from MTs N 2 Malang while the second stage feasibility test was conducted on 32 students from MTs N 3 Malang. product quality is interpreted through student questionnaire feedback after taking part in learning with BRUSLE. The quality of the product was also tested on the test results of students' comprehension skills. Data presentation is descriptive to describe the entire series of development process. The products produced in the development research can be concluded that BRUSLE Android APPS based on Hologram Augmented Reality on Engklek ethno-game-based learning is feasible and effective to use to improve students' concept understanding.
ANALISIS PREFERENSI DAN KEPUASAN KONSUMEN TERHADAP PEMBELIAN DAGING SAPI (Studi Kasus di Perumahan Taman Rahayu Kabupaten Bandung)
Authors: RIDAYANA ALLYA PUTRI
Published: February 2025

Penelitian ini telah dilaksanakan pada bulan Mei 2023 di Perumahan Taman Rahayu, Kecamatan Margaasih, Kelurahan Rahayu, Kabupaten Bandung, Jawa Barat. Tujuan dilaksanakannya penelitian ini adalah untuk menganalisis atribut yang dipertimbangkan konsumen di Perumahan Taman Rahayu Kabupaten Bandung terhadap pembelian daging sapi, untuk menganalisis preferensi dan tingkat kepuasan konsumen di Perumahan Taman Rahayu Kabupaten Bandung terhadap atribut dan pembelian daging sapi yang dibeli serta untuk menganalisis pengaruh preferensi dan kepuasan konsumen terhadap keputusan pembelian daging sapi. Metode yang digunakan dalam penelitian ini adalah survei dengan jumlah responden sebanyak 78 orang. Responden dalam penelitian ini adalah ibu rumah tangga. Analisis data dalam penelitian ini menggunakan Uji Validitas, Uji reliabilitas, Uji Chi Square, Uji Asumsi Klasik, dan Regresi Linier Berganda. Hasil penelitian menunjukkan bahwa konsumen mempertimbangkan warna daging merah cerah, tekstur yang empuk, kandungan lemak yang sedikit, dan bagian khas dalam untuk dibelinya. Konsumen biasanya membeli daging di Pasar Tradisional dengan nilai kepuasan yang tinggi setelah pembelian daging sapi. Preferensi dan kepuasan konsumen secara simultan memiliki pengaruh yang positif terhadap pembelian daging sapi, namun berbeda dengan secara parsial preferensi tidak berpengaruh positif sedangkan kepuasan berpengaruh positif.Kata Kunci: Daging Sapi, Atribut, Konsumen, Preferensi, Kepuasan
Indonesian Education Digitalization Collaboration Program For Madrasah Through The World Bank and The Ministry Of Religion
Authors: Kusuma Raden Ahmad Naufal Pranata , Widyarsa Mohammad Riza
Published: February 2025

The education digitalization program in madrasah throughout Indonesia is an initiative to overcome significant challenges in improving the quality and access to education, especially in underserved areas. The program seeks to create a more equitable educational landscape by leveraging digital technology, allowing students and educators to benefit from modern learning tools and resources. The theoretical framework guiding this research emphasizes the importance of knowledge transfer and best practices from digital education models successfully implemented in other countries. A qualitative approach analyses implementation strategies, challenges, and program outcomes. The findings show that while these initiatives have great potential to transform education, they also face obstacles such as limited infrastructure and the need for comprehensive training for educators. Ultimately, the study concludes that ongoing commitment and collaboration among stakeholders are essential to realizing the full benefits of digital education in Indonesian madrasah.
Fernando Yacamán: incesto y violencia en Todos mis padres
Authors:   , Nicasio Álvarez Israel
Published: February 2025

Fernando Yacamán, escritor mexicano nacido en 1985, es uno de los exponentes de la literatura gay contemporánea en México. Este autor plantea un tema poco explorado: la erotización de la figura paterna y de los cuerpos de hombres maduros. El objetivo de esta tesina es analizar el incesto y la violencia en las relaciones homoeróticas narradas por Yacamán en Todos mis padres. La obra de este autor es objeto de investigación en esta tesina no solo por la belleza que la constituye, también por la radicalidad de su discurso. Yacamán sigue una línea narrativa en la que sus historias posicionan a la diversidad sexual frente a la heteronorma en un sentido literario y político.
Shaping Dignities – A pluralistic and relational approach to dignity using arts-based methods
Authors: Benitez-Schaefer Florencia
Published: February 2025

While the concept of ‘dignity’ builds a cornerstone of Human Rights, as well as international and national legal structures, it has been critiqued since its inception, particularly in regards to issues of diversity. This paper argues that, if we aim to respond to the major ongoing struggles, we need to enhance our awareness about different approaches to dignity that coexist but are not equally attended or represented in the legal field. In this vein, I propose an exercise and utilize the experience of an arts-based workshop conducted recently with social scientists on the issue as material to explore different shapes of dignity. In order to engage with this material, I introduce approaches of the field of Peace Studies (Many Peaces Theory by Wolfgang Dietrich) and contemporary political philosophy (Donna Haraway), as helpful theoretical frameworks. On this base, I propose that a revised view on dignity can offer us a more relational, integrative and useful perspective in the field of law and Human Rights.
If Late, then Never or Not likely: Uptake of Orientation and Mobility Rehabilitation Training (OMRT) Among Visually Impaired Older Adults
Authors: Okonji Emeka Patrick , Connors M. Elyse , Akinsola Jonadab Oluwatosin , Ogwezzy Darlignton Chukwunalu , Durugo Samuel Ogechukwu , Leja James
Published: February 2025

Background: Visually impaired people have challenges with outdoor mobility, which underscores the need for orientation and mobility rehabilitation training (OMRT). However, awareness and uptake of OMRT among blind people remain very low in Nigeria. The study investigated the association of demographic, physical, and visual impairment-related variables with awareness and uptake of orientation and mobility rehabilitation training (OMRT) in Nigeria

Methods: A cross-sectional survey of 361 visually impaired people aged 60 years and over, with best-corrected visual acuity ≤ 20/80 (0.6 LogMAR). The Timed Up and Go (TUG) test was used to assess the risks of falling. Multiple logistic regression was used to analyse predictors of awareness and uptake of OMRT

Results: Only 26.88% of those who were aware of OMRT reported accessing Orientation and mobility rehabilitation training (OMRT). The duration of visual impairment (p=0.016), awareness of the cause of Low Vision (p=0.043), and being at the risk of falls (p < 0.001), were significantly associated with taking-up OMRT.

Conclusion: Prolonged delays in referrals for OMRT are a potential cause of apathy towards the uptake of OMRT.
Intelligent Guide Robots for People who are Blind or have Low Vision: A Review
Authors: Thiyagarajan Karthick , Kodagoda Sarath , Luu Mark , Duggan-Harper Taliah , Ritchie Doug , Prentice Kelly , Martin Jodi
Published: February 2025

According to the World Health Organization, at least 2.2 billion people worldwide are blind or have some degree of near or distance vision impairment. Guide Dogs and other existing mobility aids are valuable tools to support travel and independence for these individuals. Nevertheless, the process of training dogs to be effective mobility aids is expensive, time-consuming, and requires highly specialised expertise. With technology making significant inroads into modern society, intelligent robots that are powered by smart sensing and advanced artificial intelligence present an opportunity to improve the mobility of those with blindness or low vision where access to a Guide Dog is not available. However, developing robust and effective robotic mobility aids with static and dynamic settings for use in both indoor and outdoor environments has remained a difficult task to accomplish. This article compares the capabilities of both existing robotic mobility aids, and existing cutting-edge robotic technologies, against a set of fundamental functional mobility aid characteristics with the aim of proposing a minimum viable product to support people who are blind or have low vision in everyday mobility and navigation tasks. The functional qualities identified and examined were sensing and interpretation, obstacle avoidance and object targeting, fluid and adaptable movement and navigation, interlink of device interface and sensing-interpretation unit, device interface to user, form factor and design. The outcomes of our study indicate that while existing robotic aids are limited in scope and focused on a narrow range of functions, existing cutting-edge robotic technologies have the potential to combine to create a fully-functioning robot guide. We propose a minimum viable product using these technologies as the next step towards a fully-functioning robot guide supporting the mobility and navigation of people who are blind or have low vision.
Yielding Behaviors of Right-Turn-on-Red Drivers to a White Cane User
Authors: Bourquin Eugene A. , Fiderer Debbie , Emerson Robert Wall , Bieder Joy , Sauerburger Dona , Franck Lukas
Published: February 2025

This study tested the null hypothesis that drivers turning right-on-red will not yield (defined as declining to turn during an acceptable gap) more often when a pedestrian who used a cane was present. The researchers recorded and evaluated drivers’ gap acceptance (N=93) under three conditions: with and without a pedestrian presence at the crosswalk, and with a pedestrian present using a flagging cane strategy. Results: When there was no pedestrian present, drivers did not accept the gap (yielded) 46.7% of the time; when a pedestrian was present 25%, and when the pedestrian flagged with a cane was at the corner, significantly more at 90.3% (p < .001). Discussion: The findings indicate that even when drivers are monitoring for a traffic gap to their left side at a red signal, pedestrians who are blind using a cane with movement may increase the likelihood of vehicles yielding as they prepare and initiate a crossing.
Interactive Learning Daily Muslim Prayer Application for Children on Android at DTA Ghoniyyul Hikmah
Authors: Iezam Kamalul  Basyar  , Hernawati  , Supriyadi Sugeng , Utomo Suharjanto
Published: February 2025

Learning daily prayers is important for Muslim children. The learning process in DTA Ghonniyul Hikmah generally uses the talqin method. To make memorizing prayers easier and more engaging, interactive learning media is needed. This research developed a daily prayer application for Muslim children based on Android. The application was designed using UML and implemented with Canva, PowerPoint, Audacity, and Android Studio. The features in the daily prayer application include images, Arabic and Latin script, translations, and prayer audio. The size of the application after being built is 48 MB. The questionnaire results show a positive response from users. As many as 86.9% of users agreed that the application is easy to use, and 78.2% felt helped in memorizing prayers. Overall satisfaction reached 78.3%. The majority of respondents were satisfied with the appearance and features of the application, and felt helped in memorizing prayers. Researchers suggest for future development that this daily prayer application have additional features such as animated videos and add even more daily prayers
Engineering of Junior High School New Student Admissions System Using System Performance Based Prototype Method
Authors: Darsanto
Published: February 2025

The process of accepting new students in Junior High Schools (SMP) is currently still constrained by a conventional system that requires physical collection of registration forms, complete files, and time-consuming interviews and tests. Information related to admission procedures, requirements, fees, and registration schedules is also spread across various communication channels, making it difficult for prospective students and parents to access accurate and up-to-date information. In this context, researchers have succeeded in designing a new student admission information system by implementing the prototype method. This system has gone through Black Box Testing and evaluation with the System Usability Scale (SUS) scale, and its performance has been analyzed using the Performance, Information, Economy, Control, Efficiency, Services (PIECES) method. The results of the SUS scale calculation show an average value of 72.9, which is included in the acceptable classification indicating that the New Student Admissions (PPDB) system in the form of a prototype after evaluation can be accepted by prospective users of the prototype system. In addition, the results of the PIECES calculation show that each indicator in the evaluation and measurement of the new student admissions system is in the "very good" and "good" categories , with an average value of 6.22 to 6.56 included in the very good category, an average value of 6.09 is included in the good category
Distributed Dual-Quaternion Extended Kalman Filtering for Spacecraft Pose Estimation
Authors: Hudoba de Badyn Mathias , Binz Jonas , Iannelli Andrea , Smith Roy S.
Published: February 2025

In this paper, a distributed dual-quaternion multiplicative extended Kalman filter for the estimation of poses and velocities of individual satellites in a fleet of spacecraft is analyzed. The proposed algorithm uses both absolute and relative pose measurements between neighboring satellites in a network, allowing each individual satellite to estimate its own pose and that of its neighbors. By utilizing the distributed Kalman consensus filter, a novel sensor and state-estimate fusion procedure is proposed that allows each satellite to improve its own state estimate by sharing data with its neighbors over a communication link. A leader–follower approach, whereby only a subset of the satellites has access to an absolute pose measurement, is also examined. In this case, followers rely solely on the information provided by their neighbors, as well as relative pose measurements to those neighbors. The algorithm is tested extensively via numerical simulations, and it is shown that the approach provides a substantial improvement in performance over the scenario in which the satellites do not cooperate. A case study of satellites swarming an asteroid is presented, and the performance in the leader–follower scenario is also analyzed.
Genital contact dermatitis
Authors: Jindal Rashmi
Published: February 2025

The genital region is uniquely susceptible to both irritant and allergic contact dermatitis (ACD) due to its delicate anatomy, moist environment, and frequent exposure to potential irritants and allergens. Factors such as friction, maceration, and overuse of hygiene products significantly compromise the skin barrier, increasing the risk of dermatitis. The region’s sensitivity is further exacerbated by physiological changes, such as reduced estrogen levels in postmenopausal women, which heighten susceptibility to external agents. A detailed clinical history plays a critical role in diagnosing genital contact dermatitis (CD). Key elements include symptom onset, triggers, hygiene habits, and exposure to products used personally or by sexual partners. This thorough exploration often identifies potential irritants and allergens overlooked in a routine examination. Irritant CD (ICD) in the genital area typically presents as burning, stinging, and erythema soon after exposure to irritants. Chronic ICD may lead to scaling and lichenification. In contrast, ACD arises from delayed hypersensitivity to allergens, presenting as pruritus, erythema, and, in severe cases, vesiculobullous eruptions. Common agents implicated in ICD include soaps, urine, sweat, and certain hygiene sprays, while ACD is often triggered by allergens such as fragrances, topical medications, preservatives, and rubber components. Patch testing is a cornerstone of diagnosing genital ACD. It identifies specific allergens responsible for the dermatitis and helps in differentiating between relevant and incidental reactions. Expanding patch test series to include additional potential allergens, such as personal care products or items used by partners, enhances diagnostic accuracy. The repeat open application test is another valuable tool, particularly when patch testing yields inconclusive results. Management of genital CD primarily involves strict avoidance of identified irritants and allergens. Patients should cease using unnecessary topical medications and adopt hypoallergenic alternatives. Education on proper genital care, including the use of fragrance-free and dye-free products, is essential. Topical corticosteroids, calcineurin inhibitors, or phosphodiesterase-4 inhibitors may be prescribed for short-term relief.
IDENTIFIKASI AVIFAUNA DI KAWASAN HUTAN KEMUNING KABUPATEN TEMANGGUNG
Authors: Akhyari Annugrah Ilham , Permadani Karunia Galih , Prajoko Setiyo
Published: February 2025

Forest is one of the wetland ecosystems that has a diversity of components in it. One of the biotic diversity that exists in forest areas is avifauna. This study aims to identify avifauna in the Kemuning Forest Area, Temanggung Regency, Central Java. Observations were made using the point count method and sampling using purposive sampling technique. The results showed that there were 27 bird species from 18 families. The birds found were mostly birds from the Passeriformes order because the observation location was a forest.
Impact of octahedral aluminium sites on guest molecule adsorption in zeolites: A computational study of 5-fluorouracil in zeolite FAU
Authors: Fischer Michael
Published: February 2025

Many aluminosilicate zeolites contain octahedral aluminium sites, which may occur as extra-framework or framework-associated sites. Due to the Lewis acidity of these sites, their impact on catalytic properties has been investigated frequently. Comparatively less emphasis has been placed on their role in adsorption, despite evidence for an irreversible binding of some guest molecules like the anticancer drug 5-fluorouracil (5-FU) to octahedral Al atoms. In the present study, dispersion-corrected density functional theory (DFT) calculations and DFT-based ab initio molecular dynamics simulations (AIMD) are employed to investigate the adsorption of 5-FU at a framework-associated octahedral Al site in zeolite FAU. The calculations show that 5-FU remains coordinated to the Al atom at room temperature and in the presence of water. In contrast, 5-FU molecules adsorbed at framework protons are quickly displaced by water molecules. It is thus demonstrated that octahedral Al atoms will negatively affect the release of 5-FU from zeolite hosts in drug delivery applications. A comparison of DFT-calculated infrared (IR) spectra to literature data provides evidence that Al-coordinated 5 FU molecules were indeed present in previously investigated samples.
Ruthenium-Catalyzed One Pot Three Component Substrate Controlled Site Selective Annulation Reaction via Cascade Dehydrogenative Pathway for 4H-Benzo[d][1,3]oxazin-4-one Derivatives
Authors: Panja Subir , Paul Biprajit , Nandi Chandan , Majhi Biju , Ranu Brindaban C
Published: February 2025

A ruthenium-catalyzed chelation-assisted substrate-controlled site selective one pot three component cascade dehydrogenative annulation reaction is reported. The developed methodology proceeds for biologically active 4Hbenzo[d] [1,3] oxazin-4-one derivatives by the nucleophilic addition of amines followed by coupling of diphenyl acetylene. In addition to providing excellent yields of products, the method is also regioselective. This new protocol has been demonstrated to have an easy access to a variety of dihydroisoquinoline benzamide derivatives. The chemo-selectivity has been explained by a DFT study.
Structure-Based Drug Design to Discover Potential Hit Molecules for the Trim71 protein to prevent Congenital Hydrocephalus
Authors: Bhatia Veer , Ramamoorthy Divya
Published: February 2025

Congenital Hydrocephalus (CH) is a neurodevelopmental disorder characterized by the excessive accumulation of cerebrospinal fluid (CSF) in the brain’s ventricles. Current treatments, such as neurological shunting, pose significant risks and fail to address the underlying molecular causes, underscoring the urgent need for targeted therapeutic solutions. Recent studies have found gain-of-function mutations in the TRIM71 gene that cause abnormal binding of the TRIM71 protein to key mRNAs like lsd1 and Ctnnb1, disrupting neural differentiation. In our study, we aimed to identify potential TRIM71 inhibitors using structure-based drug design of known E3 ubiquitin ligase inhibitors. Utilizing molecular modeling tools, including Accelera’s PlayMolecule platform, DockThor, and Schrödinger’s Maestro suite, we screened and analyzed binding interactions of various compounds against the TRIM71 NHL domain (PDB: 7QRX). Our findings revealed promising candidates, with one compound exhibiting an excellent binding energy score (-30.29 kcal/mol) and favorable interactions with key residues such as Arg625, Phe766, Trp704, and Arg751. Additionally, pharmacokinetic assessments using SwissADME confirmed that Compound 5 possesses good blood-brain barrier permeability and adheres to Lipinski’s rule of five, indicating strong drug-likeness. These results highlight the potential of TRIM71-specific inhibitors in addressing the molecular pathology of CH. Future research should focus on experimental validation of these compounds through biochemical assays and in vivo studies to confirm their effectiveness in preventing CSF accumulation and supporting normal neural development in CH patients.
Multi-objective evolutionary strategy for improving semiempirical Hamiltonians in the study of enzymatic reactions at the QM/MM level of theory
Authors: Velázquez-Libera José Luís , Recabarren Rodrigo , Vöhringer-Martinez Esteban , Salgueiro Yamisleydi , Ruiz-Pernía J. Javier , Caballero Julio , Tuñón Iñaki
Published: February 2025

Quantum mechanics/molecular mechanics (QM/MM) simulations are crucial for understanding enzymatic reactions, but their accuracy depends heavily on the quantum-mechanical method used. Semiempirical methods offer computational efficiency but often struggle with accuracy in complex systems. This work presents a novel multi-objective evolutionary strategy for optimizing semiempirical Hamiltonians, specifically designed to enhance their performance in enzymatic QM/MM simulations while remaining broadly applicable to condensed-phase systems. Our methodology combines automated parameter optimization, targeting \textit{ab initio} or density functional theory (DFT)-reference potential energy surfaces, atomic charges, and gradients, with comprehensive validation through minimum free energy path (MFEP) calculations. To demonstrate its effectiveness, we applied our approach to improve the GFN2-xTB Hamiltonian using two enzymatic systems that involve hydride transfer reactions where the activation energy barrier is severely underestimated: Crotonyl-CoA carboxylase/reductase (CCR) and dihydrofolate reductase (DHFR). The optimized parameters showed significant improvements in reproducing potential and free energy surfaces, closely matching higher-level DFT calculations. Through an efficient two-stage optimization process, we first developed parameters for CCR using reaction path data, then refined these parameters for DHFR by incorporating a targeted set of additional training geometries. This strategic approach minimized the computational cost while achieving accurate descriptions of both systems, as validated through QM/MM simulations using the Adaptive String Method (ASM). Our method represents an efficient approach for optimizing semiempirical methods to study larger systems and longer timescales, with potential applications in enzymatic reaction mechanisms studies, drug design, and enzyme engineering.
RAINFALL RELIABILITY IN THE BAMENDA HIGHLANDS AND COASTAL LOWLANDS OF CAMEROON: INSIGHTS FROM NDU AND DOUALA (1957-2016)
Authors: Tume Suiven John Paul
Published: February 2025

Rainfall in coastal areas is influenced by exposure to the ocean, while the climates of the interiors are influenced by continentality. The paper bridges some methodological gaps in previous studies on Cameroon’s rainfall that emphasized interannual variability without any indices between ecological zones. The objective of this study is to compare the rainfall reliability of Douala and Ndu. Ground surface measures of mean monthly rainfall data were collected from the National Meteorological Service (Douala) and the Cameroon Tea Estate Plantation, Ndu for 60 years (1957-2016). The data were analysed using monthly averages, interannual and decadal trends, Standard Deviation (SD), Coefficient of Variation (CV) and Standardized Precipitation Index (SPI). Results revealed that the mean annual rainfall is 305.33 mm and 165.04 mm for Douala and Ndu, respectively. The interannual rainfall trend decline is steeper in Douala than in Ndu. Both stations show more dry weather conditions than the anticipated wet conditions, viz, 24 episodes of mild dryness (40%), moderate dryness 3(5%), severe dryness 3(5%) and extreme dryness 2 (3.33%) in Douala; while Ndu showed 23 episodes of mild dryness (38.33%), moderate dryness 7 (11.67%) and 1 incident of extreme dryness (1.67%). This gives 53.33% and 51.67% dry episodes for Douala and Ndu respectively. Despite these recurrent agro-meteorological droughts, rainfall is still reliable with CVs of 14.67% and 13.09% for Douala and Ndu respectively. These dynamics have implications for water-related developments. The populations are called upon to embrace sustainable environmental practices that can enhance rainfall as climate change is looming.
COMMUNAL AND STATE CONTROLLED APPROACHES IN BIODIVERSITY CONSERVATION IN AKWA IBOM STATE: A COMPARATIVE ANALYSIS
Authors: Victor Md. William Justice
Published: February 2025

This research paper is a comparative analysis of the communal and state-controlled approaches in biodiversity conservation within Akwa Ibom State. To achieve its aim, the study utilised both primary data obtained from a structured survey and secondary data from secondary sources. For the survey, a questionnaire was prepared and administered to a total of 300 respondents within both urban and rural communities of the study area. There was also a focus group discussion of 15 individuals to enhance the quality of the primary data gotten. Descriptive statistics, deductive and inductive reasoning were used to analyse the survey responses and the data drawn from other sources. The findings revealed that while communal and state-controlled biodiversity conservation approaches were quite ideal in protecting the region’s biodiversity, it would be more beneficial and cost-effective for Akwa Ibom State to adopt and invest primarily in the communal approach of biodiversity conservation.
IMPACT OF MADE-IN-NIGERIA PRODUCTS ON SOLID WASTE GENERATION AND PUBLIC HEALTH: CHALLENGES AND SOLUTIONS
Authors: Udo Saviour Sebastian , * Jacob , * Augustine
Published: February 2025

Made in Nigeria products are anticipated to expand the industrial sector, achieving proficiency and independence in production. This growth is expected to enhance the economy, create an export surplus, and integrate Nigeria into the global economy. However, increased production generates significant solid waste, posing public health and environmental challenges. This study aims to examine how Made in Nigeria products impact solid waste generation and the consequent effects on citizens’ health. A survey method was used to collect data, and a descriptive method of analysis was employed. Tables and graphs were utilized to analyze the results. The study found that open waste disposal and poorly designed landfills contribute to environmental degradation, water and air pollution, and groundwater contamination. Many Nigerians are reluctant to separate their waste, leading to ineffective waste management practices such as inadequate separation at source, collection, transportation, treatment, and clearance. The ineffective management of solid waste has resulted in degraded environmental sanitation and poor quality of life. Proper waste management is critical for public health and environmental quality, yet current practices are insufficient. The study recommends providing the Ministry of Environment with resources to improve citizens’ quality of life. Educating rural populations on modern waste management methods is essential. The government should reward firms with proper waste disposal equipment and sanction those without. Increased funding and personnel for waste management agencies, along with the involvement of the National Orientation Agency (NOA) to promote appropriate waste disposal practices, are crucial. Encouraging scavengers by providing machinery to expand their services is also recommended. This study highlights the significant impact of industrial growth on waste generation and underscores the necessity of effective waste management practices to ensure sustainable development and public health in Nigeria.
ASSESSMENT OF HEAVY METALS CONCENTRATION LEVEL IN SOIL SAMPLES FROM POWER TRANSFORMERS IN SELECTED PARTS OF IBADAN, OYO STATE, NIGERIA
Authors: Basit Oduola Ademola , Henry Otobrise , Olukayode Adeniyi Samuel , Olawale Akinola Sodiq
Published: February 2025

Trace elements with bio-importance are presence in some heavy metals but adverse effects of these elements called for concern in human system. Hence, the parameters involved must be put into consideration, such as the environment, health effects, and concentrations. The occurrences of the substance to our immediate environment, leaching processing, and their sources must be known. It is generally known that these substances are input into our immediate environment by both natural and anthropogenic means. The substance are imported into the subsurface water, flowing through water directions and finally depositing in the aquifer, or transported by erosion and end up in water and subsequently soil pollution. Heavy metals concentration level presence in soil samples from transformer oil was determined in Sango and Orita-Challenge, Ibadan, Oyo State, Nigeria using Inductively Coupled Plasma (ICP). The heavy metals determined were: (Pd, Ni, Cd, Mn, Cu, Fe, Zn, Ca, Co, K, Mg, Na, and Cr). It was affirmed from the results that some high level of heavy metals concentration from the transformer sites differs from one another, as a result of heavy metals content in the transformer oil released to the surrounding soil, while the analysis of some samples shows that the heavy metals fall below the detection limit or absent.
DEVOPS IN CHEMISTRY AND ENVIRONMENTAL SCIENCE: A COMPREHENSIVE REVIEW OF INTERDISCIPLINARY INTEGRATION
Authors: Obaigbena Alexander , Majemite Michael Tega , Dada Michael Ayorinde , Oliha Johnson Sunday , Biu Preye Winston , Daraojimba Andrew Ifesinachi
Published: February 2025

DevOps, a portmanteau of Development and Operations, has emerged as a transformative approach to software development and IT operations, emphasizing collaboration, automation, and continuous integration. In recent years, its principles have found resonance beyond the realm of traditional IT, extending into interdisciplinary fields such as Chemistry and Environmental Science. This comprehensive review explores the integration of DevOps practices in these domains, uncovering synergies and novel applications. In the realm of Chemistry, DevOps principles are reshaping laboratory workflows and accelerating the pace of research and experimentation. Automation of data collection, version control for experimental protocols, and collaborative tools for real-time communication among researchers are enhancing efficiency and reproducibility. The application of continuous integration and deployment methods to computational chemistry is streamlining the development of complex simulation models and accelerating the discovery of new compounds. Environmental Science, with its complex data sets and multifaceted challenges, is witnessing a paradigm shift with the infusion of DevOps methodologies. From monitoring air and water quality to managing large-scale environmental databases, DevOps practices are improving data accuracy, facilitating seamless collaboration among researchers, and expediting the deployment of environmental monitoring systems. The integration of DevOps in environmental modeling allows for more agile and responsive decision-making in addressing critical environmental issues. This interdisciplinary synthesis of DevOps in Chemistry and Environmental Science signifies a transformative approach to scientific research and environmental management. The cross-pollination of software development practices with scientific methodologies enhances collaboration, reproducibility, and innovation. As the boundaries between scientific disciplines blur, embracing DevOps becomes imperative for researchers and practitioners seeking to advance their fields in a rapidly evolving technological landscape. This review provides a roadmap for adopting and adapting DevOps principles in Chemistry and Environmental Science, paving the way for a more agile and interconnected scientific community.
FINANCIAL FEASIBILITY ANALYSIS OF PLEUROTUS MUSHROOM CULTIVATION USING DIFFERENT SUBSTRATES
Authors: Pokhrel Abhishek , Bohara Amrit Kumar , Subedi Susmita , Saud Subash
Published: February 2025

The study aims to evaluate the financial feasibility of cultivating Pleurotus mushrooms using various substrates including rice straw, maize stalk, banana leaves, and tree leaves. The financial analysis includes Gross return, Net return, IRR, B/C ratio, R/C ratio, and payback period followed by sensitivity analysis where the prices and gross returns are increased and decreased by 10%. Additionally, the study examines the BC ratio for each substrate. Benefit cost ratio is 1.23 indicates that mushroom cultivation is a profitable venture. The sensitivity analysis shows that the financial performance of mushroom cultivation is sensitive to changes in cost and gross return. So, increase or decrease in cost and gross return influence the outcomes of an investment. The cost was recovered in the first two harvests, which took approximately 2 months. Therefore, the payback period is determined to be two months. Among substrates evaluated, rice straw emerges as the most feasible option followed by maize stalk. On the other hand, banana leaves and tree leaves are less efficient in terms of economic return.