bluuebunny/crossref_metadata_2025 huggingface dataset:
The Occupation of Drag Through The Voices of Performers
Authors:   , Ranario Anna , Montes Alicia , Spahle Eileen , Rosales Lilibeth , Gelman Nathan
Published: January 2025

Background: Drag is a performative art form that allows individuals to explore identity, challenge societal norms, and foster community through exaggerated gendered performance. While often associated with the LGBTQ+ community, Drag remains underexplored within occupational science and occupational therapy literature.

Methods / Participants: This qualitative study employed interview methods and explored the experiences of drag performers in California, applying an occupational lens through the framework of form, function, and meaning. Five participants who performed Drag were interviewed and reflective thematic analysis was utilized to interpret qualitative data.

Findings: Our findings revealed identity as the central theme, interconnected with form, belonging, non-belonging , meaning and motivation, and resistive occupation. Findings highlight Drag as a transformative occupation that enables identity exploration, nurtures community connections, and resists societal norms. While Drag provides a space for self-expression, participants also face challenges, including exclusion within and outside the drag community.

Implications: The authors recognize that this study, situated in California at a university that supports academic freedom, afforded a unique and relatively safe opportunity to research this important topic which may not be the same in other places across the United States at this time. Our research highlights Drag’s significance as a multifaceted occupation, advocating for its recognition within occupational science and therapy to support identity exploration and resilience.
ПЕРЕДУМОВИ ТА ОРГАНІЗАЦІЙНО-ПРАВОВІ ЗАСАДИ СТВОРЕННЯ ВІЙСЬКОВОЇ СЛУЖБИ ПРАВОПОРЯДКУ ЗБРОЙНИХ СИЛ УКРАЇНИ (1991–2002)
Authors: МИХАЙЛОВ Василь
Published: January 2025

У статті досліджується становлення системи забезпечення правопорядку у Збройних Силах України. Проаналізовано воєнно-політичні та безпеково-правові передумови, що обумовили створення Військової служби правопорядку Збройних Сил України, провідні політичні, соціально-економічні, міжнародні чинники, що зумовили запровадження спеціального органу забезпечення правопорядку в ЗС України. Аналізуються моделі воєнно-поліцейських органів провідних країн світу, чий досвід враховувався при розбудові Військової служби правопорядку. Окрему увагу автор приділив забезпеченню правопорядку у ЗС України, включаючи розроблення профільного законодавства, формування структури ВСП ЗСУ, визначення її функції та напрямів діяльності.Дослідження охоплює період з 1991 по 2002 р., коли відбувався пошук форм забезпечення правопорядку у військових формуваннях України, законодавче й відомче нормативно-правове оформлення спеціального органу підтримання правопорядку у ЗС України.
ДОСВІД ЗАСТОСУВАННЯ ВІЙСЬКОВИХ ЧАСТИН І ПІДРОЗДІЛІВ СУХОПУТНИХ ВІЙСЬК ЗБРОЙНИХ СИЛ УКРАЇНИ В АНТИТЕРОРИСТИЧНІЙ ОПЕРАЦІЇ НА СХОДІ УКРАЇНИ
Authors: НАШИВОЧНІКОВ Олександр
Published: January 2025

У статті розглянуто проблемні питання, що виникли під час підготовки та застосування частин і підрозділів Сухопутних військ Збройних Сил України в антитерористичній операції, а також шляхи їх вирішення. Одним із ключових викликів, з якими зіткнулися Збройні Сили України у період 2014–2018 рр., була необхідність адекватно реагувати на дії російської армії, що зумовило перегляд деяких правил ведення бойових дій українськими підрозділами.На думку автора, досвід подолання певних вад у застосуванні Сухопутних військ Збройних Сил України у ході антитерористичної операції має сприяти підвищенню ефективності протидії широкомасштабній російській збройній агресії в умовах сьогодення та допоможе краще підготуватися до ефективної протидії будь-яким війнам у майбутньому. У статті використані як загальнонаукові методи аналізу та синтезу, так і спеціальні наукові методи, зокрема історико-генетичний та історико-типологічний.
КУЛЬТУРНЕ ЖИТТЯ УКРАЇНЦІВ У ТАБОРАХ ТИМЧАСОВО ПЕРЕМІЩЕНИХ ОСІБ НА ТЕРИТОРІЇ КРАЇН ЗАХІДНОЇ ЄВРОПИ У ПЕРШІ ПОВОЄННІ рокИ (1945–1947)
Authors: СОРОКІВСЬКА-ОБІХОД Аріадна
Published: January 2025

У статті описано культурне життя українців у таборах тимчасово переміщених осіб на території країн Західної Європи у повоєнні роки (1945–1947), головними напрямами якого стали: видавнича, освітня діяльність, розвиток мистецтва, театру, спорту, створення культурних, релігійних, наукових осередків, громадських організацій. Із 2,5–3 млн осіб українців, більшість із яких зазнали репатріації до СРСР у 1945 р., у Західній Німеччині залишилося близько 220 тис. українців. У таборах вирувало культурно-мистецьке, наукове та освітнє життя. Українцям вдалося не асимілюватися, а спільними зусиллями «збудувати Україну в мініатюрі», зберегти та примножити її, сформувавши нову політичну українську діаспору, нащадки якої передали поколінням незалежної України історичну спадщину та доклалися до формування сучасної української ідентичності.
ДІЯЛЬНІСТЬ НАУКОВО-ДОСЛІДНОГО ЦЕНТРУ ВОЄННОЇ ІСТОРІЇ НАЦІОНАЛЬНОГО УНІВЕРСИТЕТУ ОБОРОНИ УКРАЇНИ ІЗ ВИВЧЕННЯ ПЕРЕБІГУ й ДОСВІДУ РОСІЙСЬКО-УКРАЇНСЬКОЇ ВІЙНИ (2014–2024)
Authors: ШЕВЧУК Василь , ТАЛАУР Сергій , ПОКОТИЛО Олексій
Published: January 2025

У статті здійснений наукознавчий аналіз діяльності науково-дослідного центру воєнної історії Національного університету оборони України із вивчення російсько-української війни з 2014 року. До історіографічного доробку Центру віднесено науково-дослідні роботи, монографії, дисертаційні дослідження, інформаційні бюлетені, навчальні посібники, дослідницькі проєкти, історичні нариси, наукові статті. Розглядається тематична спрямованість досліджень та результати наукових пошуків. Науково-дослідний центр воєнної історії зосереджувався на дослідженнях застосування Збройних Сил України в антитерористичній операції (операції Об’єднаних сил) на території Донецької та Луганської областей, при відбитті та стримуванні широкомасштабного вторгнення російської федерації в Україну; вивченні та узагальненні бойового досвіду застосування українських військ (сил) у російсько-українській війні.
Formation Control Design of Fixed-wing UAVs Based on Model Reference Adaptive Control
Authors: Lantos Bela , Kimathi Stephen
Published: January 2025

Formation control is currently a popular field of research due to the increasing application areas of unmanned aerial vehicles. Of concern is the stability of unmanned aerial vehicles (UAVs) formation while tracking especially under the influence of disturbances, and model parameter uncertainty. Since formation of the UAV formation while tracking, especially flying involves a mutual cooperation, consensus-based techniques are more suited such that a group of UAVs are collectively coordinated to perform some tasks. In this paper, a leader–follower formation control of homogeneous fixed wing UAVs based on model reference adaptive control with an integral error control compensation is presented. Model reference adaptive control is powerful and effective for handling uncertain and varying dynamics. This proposed distributed composite control strategy with a directed graph topology, although model-dependent can be effective to suppress disturbances affecting the vehicles, while achieving consensus-based tracking of a reference path. The numerical simulation results given show the applicability of this proposed control strategy.
When mummy kills the kitty: Pet murder as a form of infanticidal attachment
Authors: Kahr Brett
Published: January 2025

Drawing upon his previous writings about "psychological infanticide" and the "infanticidal attachment", Professor Brett Kahr examines the devastating impact of parents who murder their family cats and dogs and other pets, either biologically or, indeed, symbolically. The author explores four cases of overtly psychotic adult patients, all of whom developed severe symptoms of schizophrenia in the wake of traumatic episodes of child- hood "pet murder", perpetrated by mothers or fathers. Drawing upon historical research, Kahr has noted that, in 1939, Dr John Bowlby reported a case of a patient who developed severe hysteria in the wake of the death of a family pet. Such a clinical vignette, combined with Kahr's own cases, provides significant evidence that pet bereavement, especially pet murder, may serve as an important aetiological factor in the development of significant psychopathology during adult life.
Reflective positionality and the environment of evolutionary adaptedness: Time for collaboration
Authors: Partridge Simon
Published: January 2025

This is a sequel to my articles "Enculturation, acculturation, positionality and power" (2023), and to "Boarding school syndrome: Reconsidered in social context and through the lens of attachment theory" (2021). It argues that the concepts of "positionality" and "environment of evolutionary adaptedness" overlap and complement each other in a way that has not so far been fully recognised and applied. It spells out positionality more fully, as developed in Britain by the feminist social anthropologist Judith Okely (1996, 2008, 2012). It recognises and confronts her objections to what she saw as Bowlby's patriarchal positioning of women as childcarers "in the home". I argue, with support from his co-researcher Mary Ainsworth (1965), that this was partly a misunderstanding based on Bowlby's early 1950s views before his ideas had fully matured. I re-examine Bowlby's foundational idea of the "environment of evolutionary adaptedness", now largely overlooked. I point out how this generates a radically challenging proposition: that our underlying neuro-biology is still grounded in our small group, pre-agricultural hunter–gatherer past, located some two million years ago— Bowlby's "primeval event" (see the Afterword for further elaboration). I argue that this is our primate species' "common position" despite the subsequent development of more "localised" environments of adaptedness. I draw on this to conclude that we must now definitively recognise our intrinsic, evolved need for early maternal or mother-figure nurture and concomitant security of attachment, or otherwise, as Bowlby says, psychosomatic pathology and trauma ensues. I end by highlighting that we ignore our ultimate dependence on nurturing Mother Earth at our peril.
Wading into the mess: Developing social justice leadership through systems psychodynamics
Authors: Lewis Tanya
Published: January 2025

Social justice leaders work to create more equitable social conditions, opportunities, and human rights (San Diego Foundation, 2024). They often work with people— within their organisations and with those they accompany who experience disenfranchisement within existing systems. Thus, they face highly charged conscious and unconscious emotions and demands driven by their own idealism and that of others, by their own identifications, and the identifications of those with whom they work. These leaders seek ways to continue their work through inevitable despair and disappointment as well as identifying and working towards what is possible rather than what is ideal. Systems psychodynamically informed leadership development can support social justice leaders to develop insight into themselves and their organisations, understand more about the intersections between their identifications and the systems they are in, and hone their listening and analytic skills to work more effectively in their leadership roles. The Bureau Kensington Inc. leadership programme is described as a case example of this approach.
AI and social cohesion: Threat to mankind?
Authors: Khaleelee Olya
Published: January 2025

This article outlines recent developments in AI from various positive and negative perspectives, examining its impact on the weather, on warfare, in the workplace, in the classroom, and in agriculture. It explores how such developments will impact employment by using AI to replace workers and professionals and outlines how those developments are already having an impact particularly on call centres. AI, with its capacity to create fake news and fake people, is likely to impact on communication and on relationships. This will lead to a loss of trust for key figures through the capacity of AI to be used malignly as a means of punishing, manipulating, or controlling others. The blurring of the boundary between illusion and reality and the replacement of individuals with robotics and bots in the workplace will affect the population's relationship with employers, politicians, and other powerful figures. This article considers the likely societal and global threat on populations in terms of social cohesion and explores whether the introduction of Universal Basic Income, which is being trialled extensively in various countries, would be one way of providing the stability that loss of employment will bring.
Disorders of Newborns, Babies, Children and Adults – Problems of Hips, Knees, Shanks, Feet, Spine. Rules of Prophylaxis – Nursing and Care - In Points
Authors: Karski Tomasz , Karski Jacek
Published: January 2025

It is important to diagnose the abnormalities in newborns, babies and small children and treat them early. It is essential for proper functioning of the locomotor system in every period of life - in adults is the condition of good functioning in everyday situations over the years - in sports and at work.
Epidemiological and Clinical Aspects of Patients with Blindness Following From Primary Open-Angle Glaucoma at the University Hospital Center of Ouémé-Plateau, Benin
Authors: Adouke Abouki Chakiratou Olaide , SA Gnenle Akpedje Vinciana , Amadou Alpha Bio , Nestor Aigbe , Soule Alamou , Lisette Odoulami , Ignace Sounouvou
Published: January 2025

Introduction: The authors studied the epidemiological and clinical aspects of blindness in primary open-angle glaucoma (POAG) at the Departmental University Hospital Center of Ouémé-Plateau (CHUD-OP).

Method: This descriptive and analytical cross-sectional observational study was carried out in the ophthalmology department of CHUD-OP in Porto-Novo over a period of five years. The population included all patients with unilateral or bilateral blindness related to primary open-angle glaucoma (POAG).

Results: Among the 34,565 patients seen in consultation during the study period, 483 patients were followed for POAG, among whom 104 presented blindness. The frequency of POAG was 1.40%, with a prevalence of blindness linked to POAG of 21.53%, including 16.15% for unilateral damage and 5.38% for bilateral damage. The average age of the patients was 62.78 ± 13.17 years, with a majority of patients without a history (58.65%) and a notable proportion of arterial hypertension (16.35%). Visual loss was the main reason for consultation (47.12%), with an unspecified consultation delay in more than half of the patients. Sociodemographic, clinical and therapeutic data did not show a significant association with blindness.

Conclusion: POAG-related blindness remains a major challenge in ophthalmology, highlighting the importance of early detection for its prevention and effective management.
Ser cuidador familiar de idosos com amputação maior de membro inferior: O ônus e o bônus
Authors: Figueirôa Giovana Rossi , Ramos Maria Natália , Sá Sumaia Midlej Pimentel
Published: January 2025

Este artigo aborda a temática do cuidado, explorando diferentes implicações associadas ao papel dos cuidadores familiares de idosos submetidos a amputação de membro inferior. Objetivo: Descrever e analisar as repercussões da amputação maior de membro inferior sobre os cuidadores familiares, identificando as principais dificuldades enfrentadas por eles e propondo estratégias de intervenção que possam otimizar o processo do cuidado. Metodologia: Realizou-se uma revisão da literatura narrativa de natureza qualitativa. A busca abrangeu bases de dados como PubMed, Scielo, Web of Science, PsycINFO e Google Scholar, utilizando palavras-chave em português, inglês e espanhol. Os estudos incluídos foram analisados qualitativamente, buscando identificar padrões e categorias temáticas. A heterogeneidade dos estudos foi considerada como limitações. Serão apresentados conceitos, dados sobre perfil desses cuidadores, bem como as repercussões psicológicas, físicas e sociais enfrentadas, as dificuldades na adaptação à nova rotina e o impacto na vida social e profissional. Resultados/Discussão: Idosos com AMMI necessitam de assistência física e emocional continuada que, frequentemente é fornecida por um cuidador familiar. Os impactos negativos tanto para a pessoa acometida quanto para o cuidador são amplamente reportados na literatura, assim como são descritos os benefícios dessa experiência, como o fortalecimento dos laços familiares, o desenvolvimento de novas habilidades e o crescimento pessoal. Considerações Finais: O cuidado exige uma abordagem multiprofissional, integrada e continua. Para tanto é necessário implementação de redes de apoio e estratégias para capacitação e promoção do bem-estar dos cuidadores afim de melhorar a qualidade dos cuidados prestados.
Avaliação da dor em pacientes sob cuidado intensivo: Uma revisão integrativa
Authors: Salviano Francisco Wallace Bezerra , Vieira João Emanuel Braga Amaro , Silva Metton Ribeiro Lopes e
Published: January 2025

Introdução: A avaliação da dor está relacionada a importantes resultados em pacientes sob cuidado intensivo, todavia sua mensuração permanece desafiadora, principalmente em pacientes não comunicativos, como os sedados, os intubados e os sob ventilação mecânica. Sabe-se que a avaliação ausente ou equivocada da dor pode acarretar complicações fisiológicas e psicológicas, aumentando a morbimortalidade nas Unidades de Terapia Intensiva. Ademais, é necessário destacar a importância da Behavioral Pain Scale (BPS) e da Critical-Care Pain Observation Tool (CPOT) como ferramentas de avaliação comportamental da dor para pacientes não comunicativos e sedados em Unidades de Terapia Intensiva. Outrossim, é necessário pontuar a ascensão de novas ferramentas para avaliação da dor. Objetivos: Esta revisão integrativa buscou identificar e sintetizar evidências qualitativas e quantitativas no que tange à avaliação da dor em pacientes sob cuidado intensivo. Método: Uma pesquisa abrangente de três bases de dados eletrônicas (Medline, PubMed e Scopus) foi realizada para analisar a avaliação da dor em pacientes sob cuidado intensivo. Dois autores estiveram envolvidos na seleção de estudos com base nas diretrizes do protocolo PRISMA. Resultados: Do rendimento da pesquisa original de 2802 estudos, 12 estudos foram incluídos na análise. Conclusão: A avaliação regular da intensidade da dor leva a melhores resultados e a melhor qualidade de vida a pacientes na UTI.
FORMULATION OF EMULGEL CONTAINING ROBUSTA GREEN COFFEE (COFFEA CANAPHORA) EXTRACT
Authors: Evma Rahayu Feronika , Kusnawardhani Inggiet Fitria
Published: January 2025

Robusta green coffee (Coffea canephora) contains chlorogenic acid compounds, caffeine, carbohydrates, fats, amino acids, volatile compounds, and minerals. Robusta green coffee extract is formulated in the form of emulgel as a topical application because of the potential for chlorogenic acid to improve dry skin diseases. The purpose of this study was to formulate an extract of robusta green coffee (Coffea canephora) in the form of an emulgel and to determine the physical characteristics and stability of the emulgel. The research design used is the experimental method. This research begins with the extraction of robusta green coffee using the maceration method, phytochemical screening, and the manufacture of emulgel preparations with variations in the ratio of emulsion and gel, namely F0 (1:6), F1 (1:6), F2 (3:6), and F3 (6:6). The process of making emulgel is making emulsion, making gel, and incorporating emulsion into gel. The evaluation carried out on the emulgel preparation included physical examination, determination of pH, emulsion type test, viscosity test, centrifugation test, and freeze and thaw test. The results of the physical characteristics of the emulgel preparation were good and met the requirements based on the parameters of physical examination, determination of pH, and emulsion type test and stable emulgel preparation in freeze thaw stability testing based on parameters of physical examination, determination of pH, emulsion type test, and centrifugation test. Analysis of chlorogenic acid levels in emulgel preparations using UV-Vis spectrophotometer. The levels of chlorogenic acid in the emulgel preparations did not contain chlorogenic acid (F0), 76.70% (F1), 82.77% (F2), and 79.64% (F3).
Climate and human society: adopting sea level fingerprints in next generation projections of airport flood risk
Authors: Silcox F , Cederberg G , Jaeger N , Kiam L , Powell R , Stoller P , Mitrovica JX
Published: January 2025

Assessing the impact of sea level changes on airports across the present century is a pressing issue for the rapidly expanding aviation sector and, more generally, for establishing adaptation strategies. To date, these assessments have assumed that future melting of ice sheets and glaciers leads to globally uniform sea level changes. We summarize recent geophysical research that highlights the extreme geographic variability in sea level that will occur in response to such melting—a variability captured in so-called sea level fingerprints. As a case study, we present modeling predictions of sea level change to 2100 CE based on a suite of published projections of polar ice mass flux and consider the implications of these results for airports identified as being at particularly high risk from sea level rise. We conclude that this important source of sea level variability should be incorporated—together with other processes that imprint a geographic pattern on sea level (e.g. storm surges, tides, thermosteric and ocean dynamic changes)—into projections of airport risks in a warming world.
Evoluation of biological effects of drilling fluid on marine seagrass
Nanozostera noltii Hornemann
Authors: Rudneva Irina I. , Shaida Valentin G. , Medyankina Maria V. , Shaida Oleg V.
Published: January 2025

The development of oil-gas complex in shelf zone of the seas and ocean is connected with the application of the specific chemicals, used in the processes of drilling. These components contain various chemicals, several of which are toxic and influence negative both on aquatic organisms and health of the people, using seafood. Therefore, it is important to evaluate the toxicity of of drilling fluids and their effects on the aquatic organisms inhabiting in the coastal areas of the seas and ocean. The aim of the present study was to analyze the effects of drilling fluid on marine eelgrass Zostera noltii exposed in wide spectrum of concentrations 0.004; 0.02; 0.05; 1; 5; 10; 62.5; 125; 250; 500 and 1000 mg/l. The results obtained demonstrated the non-uniform responses of the eelgrass on the tested drilling fluid, which was depended on its concentration and time of exposure.
Analysis of Destination Marketing Management in Papandayan Nature Tourism Park, Garut, West Java
Authors: Roels Ni Made Sri Puspadewi  , Setiawan Budi , Utami Nisa Rahmaniyah
Published: January 2025

As a tourist destination, various types of marketing strategies are needed in order to ensure the sustainability of the Papandayan Nature Tourism Park and maintain the natural beauty of Mount Papandayan so that it can continue to be enjoyed for a long time. This study uses Qualitative data analysis techniques using secondary data collection techniques. Data collection techniques used include Literature Review and Observation at the Papandayan Nature Tourism Park. The purpose of this study is to determine the implementation and influence of Destination Marketing Management in the Papandayan Nature Tourism Park. The results of this study are that the Papandayan Nature Tourism Park has so far implemented many marketing strategies which are marked by an increase in visitors each year, adequate infrastructure, various types of attractions provided and good responses from visitors. The suggestion that can be given from this study is that in the future it would be better if the Papandayan Nature Tourism Park could promote itself more, especially using various platforms such as Websites or Social Media to introduce the Tourist Destination to a wider audience. This is because currently the information available in the media is still relatively minimal and it is still difficult to find out the exact information contained in Papandayan unless tourists visit the place first or see the reviews left by previous visitors.
Escalating the Spirituality Values Integration into School Curriculum and Holistic Implementation: Strong Leadership Supports
Authors: Juharyanto Juharyanto , Binti Syariff M. Fuad Dayang Rafidah , Rochmawati Rochmawati , Lesmana Indra , Fauzan Shobiry Ahmad Kholish
Published: January 2025

This study aims to analyze the strategy of escalating the integration of spiritual values into the curriculum and its holistic implementation through the support of effective principal leadership. This study was conducted qualitatively in four madrasahs, where data collection was carried out through in-depth interviews, non-participant observation, and documentation. The collected data were discussed in FGDs with 144 participants online and offline to ensure their validity. The results of this study include: 1) convergence of opinions among all stakeholders agreed to include and combine four essential spiritual categories, namely tauhid (Oneness of God), akhlak (good morals), Worship, and Jihad (struggle), into the education curriculum, following common beliefs and the results of deliberation; 2) five strategies that are practically implemented into the following holistic and integrative activities, including; (1) establishing a curriculum integration escalation policy; (2) integrated into the implementation of all materials; (3) carried out jointly between schools and parents; (4) controlled administratively through a liaison book and daily pocket book (a'malul yaum); and (5) carried out in various real actions; 3) leaders have a clear vision and are the best role models. This research provides implications about the importance of visionary leaders in strengthening spiritual values in their curriculum in a planned, systematic, and total manner.
Bridging Generations: Exploring the Role of Organizational Culture in Shaping Generation Z’s Identity in Higher Education
Authors: Burhan Burhan , Asmiraty Asmiraty , Sugianto Hendi
Published: January 2025

This study aims to analyze the role of local wisdom-based organizational culture in shaping the identity of Generation Z in higher education so that they can adapt to digital challenges and rapid social change. This study uses a qualitative approach with in-depth interview techniques, observation, and documentation. Data were analyzed thematically by coding, pattern identification, triangulation, and member checking to ensure the accuracy of the research data. The study results indicate that organizational culture in higher education plays an important role in guiding values and norms, helping students internalize social values, actively engage in campus activities, develop social networks, and improve social skills. Students become resilient and adapt well, aligning traditional values with modern demands. The implications of this study indicate that a solid and inclusive organizational culture can support the formation of a strong, flexible, and principled student identity amidst rapid changes in the digital era. These findings can guide educational institutions in designing policies that support the development of student character and integrity development in the digital era.
Beyond the Classroom: Total Quality Management and Digital Innovation in Education
Authors: Rada Rada , Dewi Indah Kusuma , Mashar Ali , Alamsyah Riko
Published: January 2025

This study aims to analyze the implementation of digital education innovation based on Total Quality Management (TQM) in Islamic Boarding Schools in the Bangka Belitung Islands. This study uses a qualitative approach with a case study design, where data is collected through interviews, observations, and documentation, then analyzed descriptively with the Interactive Analysis Model from Miles & Huberman, including data reduction, data display, and data verification. The study results indicate that the commitment of Islamic boarding school management is significant in providing adequate digital infrastructure for learning. Implementing TQM in Islamic boarding schools requires the involvement of all elements of the school, including managers, teachers, and students. Designing a digital-based curriculum that integrates local wisdom also plays a role in maintaining Islamic boarding school values while meeting the demands of technological developments. In addition, enhancing resource capacity, especially teachers, through technology training is the key to success in implementing digital media. Focusing on user satisfaction, both students and teachers, is also essential to ensure the success of digital learning. The implications of this study indicate that implementing digital-based TQM in Islamic boarding schools not only strengthens the quality of education but also introduces a technology-based approach relevant to the needs of the times without ignoring the traditional values of Islamic boarding schools.
PEMBANGUNAN BERKELANJUTAN BERBASIS POTENSI TEKNOLOGI, INOVASI, DAN PEMBERDAYAAN SOSIAL EKONOMI MASYARAKAT DI KABUPATEN LAMPUNG TENGAH
Authors: Suwandi Suwandi , Meilinda Selvi Diana
Published: January 2025

Belum optimalnya sistem infomasi dan tekonologi untuk menyusun dan memonitor perencanaan, serta kurangnya inovasi dan program pemberdayaan sosial oleh Badan Perencanaan dan Pembangunan (Bappeda) Kabupaten Lampung Tengah yang diindikasikan akan berdampak pada tidak tercapainya tujuan pembangunan berkelanjutan (TPB)/Sustainable Development Goals (SDGs) menarik perhatian penulis untuk memberikan gagasan mengenai potensi pengembangan teknologi, inovasi, dan pemberdayaan sosial ekonomi masyarakat kepada Bappeda Kabupaten Lampung Tengah. Penelitian ini bertujuan untuk menjelaskan bagaimana peran Bappeda dalam mendukung pembangunan berkelanjutan berbasis potensi, teknologi, inovasi, dan pemberdayaan sosial ekonomi masyarakat di Kabupaten Lampung Tengah. Dengan menggunakan studi kepustakaan dan analisis deskriptif sumber data berupa dokumen yang terkait dengan fokus penelitian dianalisis secara kritis dan mendalam sehingga memperoleh jawaban yang komprehensif berkaitan dengan pertanyaan penelitian. Hasil penelitian menunjukan bahwa pada Kabupaten lampung Tengah memiliki 15 isu strategis dan 6 masalah yang dimiliki oleh Bappeda Lampung Tengah. Gagasan penulis terhadap potensi pengembangan teknologi, inovasi, dan pengembangan sosial ekonomi masyarakat dapat dilakukan dengan upaya kolaboratif berbagai stakeholder sehingga seluruh proses pengembangan teknologi, inovasi, dan pengembangan sosial ekonomi masyarakat dapat dilakukan dengan baik. Harapannya kompleksitas masalah yang terjadi dapat diselesaikan dengan seluruh potensi sumber daya di Lampung Tengah dengan dukungan melalui beberapa program kegiatan yang memiliki tujuan untuk mencapai Pembangunan berkelanjutan provinsi lampung 2030.
Research on upper limb rehabilitation assessment model based on belief rule base
Authors: Jiang Dawei , Zhao Zixu , Wang Lijun , Zhang Chao , He Meixuan , Ji Tiejun
Published: January 2025

Rehabilitation assessments hold an irreplaceable role in the field of rehabilitative therapy. However, due to the subjectivity of traditional physicians and the variability of patient conditions, this leads to a lack of detailed grading and inaccurate assessment results. To address this issue, we developed an upper limb rehabilitation evaluation model. This model integrates muscle strength assessment methods and the Belief Rule Base (BRB), along with qualitative knowledge such as clinical rehabilitation theories and expert experiences. It also utilizes training data from actual patients, collected by an upper limb rehabilitation robot. We then optimized the BRB model’s evaluation accuracy using the Fmincon algorithm and compared its result with commonly used methods such as the Back Propagation (BP) neural network and Support Vector Machine (SVM). This comparison validated the effectiveness and advancement of our BRB approach. This work has laid both a theoretical and practical groundwork for developing a clinical decision support system based on the BRB for upper limb rehabilitation evaluations.
Development of an interpretable model for foot soft tissue stiffness based on gait plantar pressure analysis
Authors: Bai Xiaotian , Hou Xiao , Lv Dazhi , Wei Jialin , Song Yiling , Tang Zhengyan , Huo Hongfeng , Liu Jingmin
Published: January 2025

Purpose

Plantar soft tissue properties affect foot biomechanics during movement. This study aims to explore the relationship between plantar pressure features and soft tissue stiffness through interpretable neural network model. The findings could inform orthotic insole design.

Methods

A sample of 30 healthy young male subjects with normal feet were recruited (age 23.56 ± 3.28 years, height 1.76 ± 0.04 m, weight 72.21 ± 5.69 kg). Plantar pressure data were collected during 5 trials at the subjects’ preferred walking speed (1.15 ± 0.04 m/s). Foot soft tissue stiffness was recorded using a MyotonPRO biological soft tissue stiffness meter before each walking trial. A backpropagation neural network, optimized by integrating particle swarm optimization and genetic algorithm, was constructed to predict foot soft tissue stiffness using plantar pressure data collected during walking. Mean impact value analysis was conducted in parallel to investigate the relative importance of different plantar pressure features.

Results

The predicted values for the training set are slightly higher than the actual values (MBE = 0.77N/m, RMSE = 11.89 N/m), with a maximum relative error of 7.82% and an average relative error of 1.98%, and the predicted values for the test set are slightly lower than the actual values (MBE = −4.43N/m, RMSE = 14.73 N/m), with a maximum relative error of 7.35% and an average relative error of 2.55%. Regions with highest contribution rates to foot soft tissue stiffness prediction were the third metatarsal (13.58%), fourth metatarsal (14.71%), midfoot (12.43%) and medial heel (12.58%) regions, which accounted for 53.3% of total contribution.

Conclusion

The pressure features in the medial heel, midfoot area, and lateral mid-metatarsal regions during walking can better reflect plantar soft tissue stiffness. Future studies should ensure measurement stability of this region and refine insole designs to mitigate plantar soft tissue fatigue in the specified areas.
Effects of polylactic acid scaffolds with various orientations and diameters on osteogenesis and angiogenesis
Authors: Xu Yun Rong , Tang Dai Yuan , Xiao Zhen Ping , Huang Zai Tian , Zhang Heng Rui , Tang Zi Wen , He Fei
Published: January 2025

Researchers in the field of regenerative medicine have consistently focused on the biomimetic design of engineered bone materials on the basis of the microstructure of natural bone tissue. Additionally, the effects of the micromorphological characteristics of these materials on angiogenesis have garnered increasing attention. In vitro, the orientation and diameter of scaffold materials can exert different effects on osteogenesis and vascularisation. However, more comprehensive investigations, including in vivo studies, are required to confirm the results observed in vitro. Accordingly, in the present study, fibre scaffolds with various orientations and diameters were prepared by electrospinning with polylactic acid. The effects of the micromorphological characteristics of these scaffolds with different orientations and diameters on osteogenesis and vascularisation were systematically studied via in vivo experiments. The scaffolds with aligned micromorphological features positively affected osteogenesis and vascularisation, which indicated that such characteristics could be considered crucial factors when designing materials for bone repair.
Optogenetic control of mitochondrial aggregation and function
Authors: Zhang Luhao , Liu Xuechun , Zhu Min , Yao Yuanfa , Liu Zhichao , Zhang Xianming , Deng Xin , Wang Yi , Duan Liting , Guo Xiaogang , Fu Junfen , Xu Yingke
Published: January 2025

The balance of mitochondrial fission and fusion plays an important role in maintaining the stability of cellular homeostasis. Abnormal mitochondrial fission and fragmentation have been shown to be associated with oxidative stress, which causes a variety of human diseases from neurodegeneration disease to cancer. Therefore, the induction of mitochondrial aggregation and fusion may provide an alternative approach to alleviate these conditions. Here, an optogenetic-based mitochondrial aggregation system (Opto-MitoA) developed, which is based on the CRY2clust/CIBN light-sensitive module. Upon blue light illumination, CRY2clust relocates from the cytosol to mitochondria where it induces mitochondrial aggregation by CRY2clust homo-oligomerization and CRY2clust-CIBN hetero-dimerization. Our functional experiments demonstrate that Opto-MitoA-induced mitochondrial aggregation potently alleviates niclosamide-caused cell dysfunction in ATP production. This study establishes a novel optogenetic-based strategy to regulate mitochondrial dynamics in cells, which may provide a potential therapy for treating mitochondrial-related diseases.
Design and development of a low-cost, eco-friendly forklift for sustainable logistics management
Authors: Jalal Asif , Farooq Muhammad , Anwer Izza , Hayat Nasir , Munir Adeel , Zahid Imran , Akbar Noreen Sher , Hamza M. , Nouman M. , Riaz Fahid
Published: January 2025

The U.S. Occupational Safety and Health Administration’s (OSHA) most recent estimates show that between 35,000 and 62,000 injuries occur every year due to forklift-related accidents. According to the National Safety Council (NSC) data, approximately 78 fatalities are reported every year. Moreover, manual loading and unloading of heavy items is time-consuming and poses significant risks to workers in small and crowded warehouses. To address these safety and efficiency concerns cost-effectively, an automated robotic forklift prototype was developed. The key features of this industrial robot include full rotational mobility with a zero-degree turning radius, which reduces the time and space required to turn around corners. It can be operated remotely via a mobile phone using Bluetooth or wi-fi. The motion control system, based on the ESP-32 microcontroller, significantly enhances its operational efficiency compared to manual operation. This study evaluates the performance of the robotic forklift prototype, cost-effectiveness, with loading and unloading capabilities as effective solutions to the challenges faced by workers. Additionally, structural analysis using Ansys confirmed that the design can safely withstand forces 60% greater than the intended design load of 50 N. Furthermore, the maximum stress experienced by the fork is 67% below the material yield strength, further demonstrating robustness and reliability. The integration of advanced technology and Eco-friendly design positions this forklift as a viable and sustainable option for improving material handling in various industrial sectors.
Social media for public participation in urban planning in China based on place attachment-- a case of the Guangzhou banyan tree incident
Authors: Ouyang Yifei , Bai Xiaohe
Published: January 2025

Given the current low level of public participation and limited channels of participation in Chinese urban planning. Social media has become an important platform for public participation in China. Taking the banyan tree relocation and felling incident in Guangzhou City as an example. This paper explores how social media-facilitated public participation can effectively influence urban planning decisions through case study and discourse power analysis. It is found that place attachment may serve as a significant motivator for public participation in urban planning. Social media plays a dual role in this process. On one hand, it can improve the effectiveness of public participation in urban planning and ultimately fulfil the role of advancing democratic government decision-making. On the other hand, the paper reveals challenges such as information homogenization, emotionalized communication, and elite dominance. These issues underscore the need for further improvements in regulatory mechanisms and technical support. Therefore, future urban planning policies should take people's emotions into account, and also need to accelerate the construction of improved systems, mechanisms and technologies for social media public participation to achieve high-level public participation goals.
How to facilitate peer support – learnings from the development of a peer support program for people with T2DM via instant messaging service to improve diabetes self-management
Authors: Hemetek Ursula , Aubram Tatjana , Grüblbauer Johanna , Höld Elisabeth
Published: January 2025

This study explores the use of Instant Messaging Services (IMS) for peer support among individuals with Type 2 Diabetes Mellitus (T2DM). Leveraging the popularity of IMS within the affected age group, the DiabPeerS study implemented a peer support intervention aimed at improving long-term blood glucose levels (HbA1c) in a randomized controlled trial (RCT). This article describes the development and acceptance of the IMS intervention used in the DiabPeerS study. The intervention included a communication strategy and content designed for lay moderators to facilitate group interaction among people with Type 2 Diabetes mellitus (PWT2D). The intervention’s acceptance was determined by conducting participant interviews, moderator meetings, and analysis of IMS chat protocols. Results indicate that the intervention was well-received, with participants engaging in meaningful exchange about diabetes self-management (DSM). However, those less familiar with online communication may benefit from preparational training and initial face-to-face meetings could enhance group cohesion. This research offers insights into the practical application of IMS for diabetes peer support, highlighting both its benefits and room for improvement.
Polarity and migration of cranial and cardiac neural crest cells: underlying molecular mechanisms and disease implications
Authors: Salinas Esteban , Ruano-Rivadeneira Francis , Leal Juan Ignacio , Caprile Teresa , Torrejón Marcela , Arriagada Cecilia
Published: January 2025

The Neural Crest cells are multipotent progenitor cells formed at the neural plate border that differentiate and give rise to a wide range of cell types and organs. Directional migration of NC cells and their correct positioning at target sites are essential during embryonic development, and defects in these processes results in congenital diseases. The NC migration begins with the epithelial-mesenchymal transition and extracellular matrix remodeling. The main cellular mechanisms that sustain this migration include contact inhibition of locomotion, co-attraction, chemotaxis and mechanical cues from the surrounding environment, all regulated by proteins that orchestrate cell polarity and motility. In this review we highlight the molecular mechanisms involved in neural crest cell migration and polarity, focusing on the role of small GTPases, Heterotrimeric G proteins and planar cell polarity complex. Here, we also discuss different congenital diseases caused by altered NC cell migration.
Curcumin encapsulated in PAMAM dendrimers for the therapeutic treatment of ischemic stroke in rats
Authors: Stadler Justin , Garmo Lucas G. , Doyle David , Cheng Chin-I. , Richardson Garrett , Waheed Zain , Tofan Tim , Srinageshwar Bhairavi , Sharma Ajit , Petersen Robert B. , Dunbar Gary L. , Rossignol Julien
Published: January 2025

Introduction

Ischemic stroke is a devastating neurovascular condition that occurs when cerebral tissue fails to receive an adequate supply of oxygen. Despite being a leading cause of death and disability worldwide, therapeutic interventions are currently limited. Polyamidoamine (PAMAM) dendrimers are nanomolecules commonly used in biomedical applications due to their ability to encapsulate small-molecules and improve their pharmacokinetic properties. Curcumin is known to have anti-inflammatory and antioxidant effects yet suffers from poor solubility and bioavailability. The purpose of this study is to investigate the efficacy of curcumin encapsulated in PAMAM dendrimers as a potential therapeutic treatment for ischemic stroke by studying post-stroke lesion size, astrocyte reactivity, and functional recovery in a rat model of cerebral ischemia.

Methods

Forty-eight male and female Sprague-Dawley rats (280–380 g) underwent either a 90-min middle cerebral artery occlusion (MCAo) or sham surgery before receiving one of four treatments: (1) Hanks’ balanced salt solution (HBSS) control, (2) empty dendrimer control, (3) curcumin control, or (4) curcumin encapsulated in PAMAM dendrimer. Neurobehavioral outcomes were evaluated at 1-, 3-, 5-, and 7-day post-surgery, after which animals were euthanized on day 8 to assess infarct volume and GFAP immunoreactivity.

Results

Animals that received formulations containing dendrimers (curcumin encapsulated in dendrimers or empty dendrimers) demonstrated significantly lower levels of GFAP immunoreactivity and improved functional recovery, including weight and neurobehavioral scores, compared to the formulations that did not contain dendrimers (curcumin and HBSS control). Additionally, the dendrimer-curcumin treatment group exhibited a significantly improved paw laterality index over the course of the study compared with the other three treatment groups.

Conclusion

Although the post-stroke administration of curcumin encapsulated in PAMAM dendrimers modulates the astrocytic response and promotes functional recovery following ischemic stroke in rats, its therapeutic benefits may be driven by PAMAM dendrimers as the empty dendrimer treatment group also showed significant improvements post-stroke. Further investigation regarding PAMAM dendrimers in treating neuroinflammatory conditions remains warranted.
The role of autophagy in Graves disease: knowns and unknowns
Authors: Al-kuraishy Hayder M. , Sulaiman Ghassan M. , Mohammed Hamdoon A. , Abu-Alghayth Mohammed H. , Albukhaty Salim , Jabir Majid S. , Albuhadily Ali K. , Al-Gareeb Ali I. , Klionsky Daniel J. , Abomughaid Mosleh M.
Published: January 2025

Graves disease (GD), an autoimmune disease affects the thyroid gland, results in hyperthyroidisms and goiter. The main cause of GD is not clearly defined; however, stimulating autoantibodies for thyroid stimulating hormone receptor (TSHR) known as thyroid-stimulating immunoglobulins (TSIs) are the primary proposed mechanism. The TSI activation of TSHRs of thyroid gland results in excessive release of thyroid hormones with the subsequent development of hyperthyroidism and goiter. The cellular process of macroautophagy/autophagy is implicated in the pathogenesis of GD and other thyroid diseases. Autophagy plays a critical role in many thyroid diseases and in different stages of the same disease through modulation of immunity and the inflammatory response. In addition, autophagy is also implicated in the pathogenesis of thyroid-associated ophthalmopathy (TAO). However, the exact role of autophagy in GD is not well explained. Therefore, this review discusses how autophagy is intricately involved in the pathogenesis of GD regarding its protective and harmful effects.