bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect Of Delay Time And Storage Temperature On The Results Of Urine Leukocyte Examination In Patients Of Urinary Tract Infection (UTI)
Authors: Krisdianti Rika , Puspitasari Puspitasari , Aliviameita Andika
Published: August 2023

Urinary Tract Infection (UTI) is a condition where there are microorganisms that multiply in the urinary tract causing inflammation and bacteriuria. The delay in the examination results in an error in diagnosis, the examination must be carried out >1 hour and a maximum of 2 hours after the voiding process at a temperature of 20-25℃ and the delay can be done a maximum of 4 hours at a temperature of 2-8℃. The study was conducted in June 2022. The study was conducted at SMK Muhammadiyah 1 Pandaan. UTI sampling at Sahabat Hospital in Suwayuwo Sukorejo. The purpose of this study was to determine the effect of delay time and storage temperature on the results of urine leukocyte examination in UTI patients. This study used an experimental method using 35 urine samples. The statistical test used the Two Way Anova test with a 95% confidence level and the inaccuracy limit of (α) = 0.05. Based on the results of the Two Way Anova test between storage temperature and delay in urine leukocytes, a significance value of 0.981 (p>0.05), it can be concluded that Ha is rejected and Ho is accepted, meaning that there is no interaction effect between the length of time delay and storage temperature on leukocyte results. urine in UTI patients.
Prevalence Of Helmint Infection In Cat’s Feces In Surabaya City
Authors: Rohmayani Vella , Arimurti Anindita Riesti Retno , Romadhon Nurhidayatullah , Lihabi Lihabi
Published: August 2023

Cats are one of the most popular animals because of their cute and tame appearance. Just like other organism, cats can become infected worms if they are not kept clean. Cats infected with worms will initially lose their appetite, over time they will lose weight. Cats infected with worms, if kept and not treated continuously, can transmit to cat owners (humans). This study aims to determine the prevalence of parasitic worm infection in cat feces in the city of Surabaya, and to compare the prevalence of parasitic worm infection in domesticated cats with cats living wild in the city of Surabaya. The samples used in this study were 100 faecal samples, which were taken from 50 cats that live in the wild and from 50 live cats that are kept. Examination of faecal samples was carried out directly and indirectly using the saturated NaCl debris method, the data obtained will be presented descriptively and analyzed using the Chi-square test. Based on the results of the research conducted, the prevalence of worm infection in feral cat feces was 60%, while in domestic cats the prevalence was 10%. The types of worms that were found were Toxocara spp., Ancylostoma spp., Diphyllobothrium spp., and Trichuris spp. Based on the Chi-square test, it can be concluded that there is a significant relationship (P<0.05) between the prevalence of parasitic worm infection in domesticated cats and cats that live in the wild.
Photophysical image analysis: parameter estimation, thresholding and segmentation for images from electron-multiplying charge-coupled devices
Authors: Ambjörnsson Tobias , Krog Jens , Dvirnas Albertas , Ström Oskar , Beech Jason , Tegenfeldt Jonas , Muller Vilhelm , Westerlund Fredrik
Published: August 2023

Images acquired in fluorescence microscopy are subject to two types of noise: stochasticity in the arrival of photons at the imaging camera and subsequent noise induced by the detection system of the camera. In here, we introduce the concept photophysical image analysis (PIA) and an associated pipeline for images recorded by electron-multiplying charge-coupled device (EMCCD) cameras. Our non-heuristic methods are based on the sole assumption that the background photon arrival to the detector are described by a stationary Poisson process. We make no assumption about the signal photon statistics. We base our approach on a new closed-form analytic expression for the characteristic function for the image count recorded in an EMCCD camera. Two common image analysis tasks are addressed: thresholding, i.e., separating the image pixels into background and signal pixels based on recorded counts in each pixel, and segmentation, i.e., identifying "objects" in the image. Our pipeline for tackling these tasks use a procedure for camera noise model parameter estimation and a novel method for estimation of the photon statistics parameters directly from an image which contains both background and signal pixels. Utilizing these parameter estimates, we then introduce a new probabilistic thresholding method, where the accuracy of the thresholding is benchmarked against the Otsu method. We lastly present a segmentation method which uses the thresholding results as input. We demonstrate how the pipeline can be successfully applied to segmentation of synthetic images and experimental images of fluorescent beads and lung cell nuclei. The associated publicly available software opens up for fully automated, unsupervised, probabilistic photophysical image analysis.
Sparse-Firing Regularization Methods for Spiking Neural Networks with Time-to-First-Spike Coding
Authors: Sakemi Yusuke , Yamamoto Kakei , Hosomi Takeo , Aihara Kazuyuki
Published: August 2023

The training of multilayer spiking neural networks (SNNs) using the error backpropagation algorithm has made significant progress in recent years. Among the various training schemes, the error backpropagation method that directly uses the firing time of neurons has attracted considerable attention because it can realize ideal temporal coding.
This method uses time-to-first-spike (TTFS) coding, in which each neuron fires at most once, and this restriction on the number of firings enables information to be processed at a very low firing frequency.
This low firing frequency increases the energy efficiency of information processing in SNNs.
However, only an upper limit has been provided for TTFS-coded SNNs, and the information-processing capability of SNNs at lower firing frequencies has not been fully investigated.
In this paper, we propose two spike-timing-based sparse-firing (SSR) regularization methods to further reduce the firing frequency of TTFS-coded SNNs.
Both methods are characterized by the fact that they only require information about the firing timing and associated weights.
The effects of these regularization methods were investigated on the MNIST, Fashion-MNIST, and CIFAR-10 datasets using multilayer perceptron networks and convolutional neural network structures.
A Category-Aware Network for Next POI Recommendation with Long- and Short-Term Preferences
Authors: Wang Yu , Liu An , Jiang Fan
Published: August 2023

As an important branch of recommendation systems, POI recommendation recommends the next Point of Interest (PoI) to users, which can effectively solve the problem of data redundancy in the information era. Researchers are committed to mining spatial-temporal information to model users' dynamic preferences and behavior patterns. However, suffering from the inherent sparsity issue of check-in records, existing methods only focus on spatial-temporal information and ignore the semantic information hidden in the users' check-in sequences. This kind of semantic information often embodies close relationship of user-POI and POI-POI. To this end, we introduce POI category information and propose a category-aware network with long- and short-term preferences (LSCAN for short) for next POI recommendation. By modeling the competition/cooperation relationship between POIs, we can have a deeper insight into user behavior patterns. Furthermore, the dynamic changes of users' interests, i.e., long-term and short-term preferences, play a significant role when users make decision. Therefore, we design a dynamic fusion mechanism to combine them. Finally, we study the performance of the proposed method on three real-world datasets. The experimental results show that LSCAN consistently outperforms the state-of-the-art approaches for next POI recommendation.
Adult-Type Neuronal Intranuclear Inclusion Disease with Limb Tremor Onset: Case Report and Literature Review
Authors: Wang Shuning , Zhu Hui , Liu Jingyao , Liu Hongping , Zhang Rensheng , Gao Hongyu , Wang Yushi , Li Yang
Published: August 2023

Background: Neuronal intranuclear inclusion disease (NIID) is a slowly progressing neurodegenerative disorder characterized by pathological features and eosinophilic intranuclear inclusions found in the central and peripheral nervous systems as well as in visceral organs. Herein, we report the case of a 62-year-old woman who presented with limb tremors and gradually developed cognitive impairment and unresponsiveness.
Case presentation: A 62-year-old woman was admitted to our hospital because of limb tremors for 7 years, along with mental disorders,slow reactions, and gait instability for 5 years. Brain magnetic resonance imaging revealed high-intensity signals in the corpus callosum and corticomedullary junction on diffusion-weighted imaging. Additionally, fluid-attenuated inversion recovery sequences showed high-intensity signals in the bilateral cerebellar vermis and middle cerebellar peduncle. Next, cerebrospinal fluid examination indicated a pressure of 95 mmH2O, positive Pandy’s test, glucose level of 4.0 mmol/L, protein level of 1100 mg/L, and chloride level of 122 mmol/L. Other laboratory tests showed no significant abnormalities. We considered a diagnosis of NIID. Subsequently, a skin biopsy was performed 10 cm above the left lateral malleolus. P62-immunoreactive abnormal material was confirmed in individual fibroblasts. Ultrathin sectioning and imaging revealed spherical, lightly stained, short filamentous inclusion structures in fibroblast nuclei. Genetic testing found pathogenic repetitions of GGC in NOTCH2NLC.
Conclusion: NIID is a rare clinically heterogeneous disease. In clinical work, a diagnosis of NIID should be considered when patients present predominantly with limb tremors and persistent abnormal high-intensity signals in the corpus callosum on diffusion-weighted imaging; NIID should especially be considered when patients do not demonstrate tendon reflexes. Long-term follow-up should be conducted to confirm the diagnosis, treatment, and prognosis of the disease.
Performance in Myoelectric Pattern Recognition Improves with transcranial Direct Current Stimulation
Authors: Damercheli Shahrzad , Morrenhof Kelly , Ortiz-Catalan Max
Published: August 2023

Sensorimotor impairments, resulting from conditions like stroke and amputations, can profoundly impact an individual’s functional abilities and overall quality of life. Assistive and rehabilitation devices such as prostheses, exo-skeletons, and serious gaming in virtual environments can help to restore some degree of function and alleviate pain after sensorimotor impairments. Myoelectric Pattern Recognition (MPR) has gained popularity in the past decades as it provides superior control over said devices, and therefore efforts to facilitate and improve performance in MPR can result in better rehabilitation outcomes. One possibility to enhance MPR is to employ transcranial Direct Current Stimulation (tDCS) to facilitate motor learning. Twelve healthy able-bodied individuals participated in this crossover study to determine the effect of tDCS on MPR performance. Baseline training was followed by two sessions of either sham or anodal tDCS using the dominant and non-dominant arms. Assignments were randomized, and the MPR task consisted of 11 different hand/wrist movements, including rest or no movement. Surface electrodes were used to record EMG and the MPR open-source platform, BioPatRec, was used for decoding motor volition in real-time. The Motion Test was used to evaluate performance. We hypothesized that using anodal tDCS to increase the excitability of the primary motor cortex associated with non-dominant side in able-bodied individuals, will improve motor learning and thus MPR performance. Overall, we found that tDCS enhanced MPR performance, particularly in the non-dominant side. We were able to reject the null hypothesis and improvements in the Motion Test’s Completion Rate during tDCS (28% change, p-value: 0.023) indicate its potential as an adjunctive tool to enhance MPR and motor learning. tDCS appears promising as a tool to enhance the learning phase of using assistive devices using MPR, such as myoelectric prostheses.
Effect of Nb2O5 coating on the corrosion resistance of the 7050-T7451 aluminium alloy
Authors: Ferreira Murilo Oliveira Alves , Teixeira Gabriella Terezinha Lima , Leite Natália Bueno , Gelamo Rogério Valentim , Pinto Haroldo Cavalcanti , Aoki Idalina Vieira , Moreto Jeferson Aparecido
Published: August 2023

The aircraft industry has been searching for new materials to be used in their aircrafts, which provide good mechanical and corrosive properties. The 7xxx series aluminium alloys are widely used in structural components. However, these alloys are susceptible to localised corrosion processes when exposed to an aggressive environment, which affect their lifetime and performance. Surface treatment appears as a powerful tool to improve the corrosion resistance of these alloys, since the coating may act as a protective physical barrier. This work aims to present an innovative and applied research for the development of the Nb2O5 thin films on the 7050-T7451 aluminium alloy surface by using the reactive sputtering technique. The open circuit potential, potentiodynamic polarization, electrochemical impedance spectroscopy as well as immersion tests were used to access the corrosion behaviour of the 7050-T7451 aluminium alloy in 0.6 mol L-1 NaCl solution. The morphology of the coated and uncoated specimens was verified by using optical microscopy, AFM and SEM/EDX techniques. Results demonstrated a difference of about 315 mV between the pitting potential (Epitting) and corrosion potential (Ecorr) for the coated material, indicating the positive effect of Nb2O5 thin films on the corrosion resistance of the alloy. In addition, EIS results displayed the reactive sputtering technique was advantageous, since the impedance modulus increased significantly. Finally, the EIS measurements corroborate with the AFM results, showing the Nb2O5 coating at the beginning of the corrosion tests is about 300 nm in thickness. To the best of our acknowledgement, this is the first study concerning the improvement of the corrosion properties of 7050-T7451 aluminium alloy by using the methodology presented in this work.
The influence of different production systems on welfare in a new layer hybrid
Authors: KURŞUN KADRİYE , Abdallah Nasir , Boga Yunus Emre , Baylan Mikail
Published: August 2023

This study was conducted to investigate the influence of two different production systems on the welfare of a new Turkish egg laying hybrid known as the Akbay. A total of 180 Akbay hens at the 80th wk of production either housed in conventional cages or in free range systems were used. Live body weight at the 80th wk of production, as well as the weight of immune organs and liver, was recorded. Plumage damage, foot lesions, stress, and fear were examined. The results revealed that the live body weight at the 80th wk of production was significantly (P ≤ 0.05) higher in the free-range birds compared to those housed in cages. The rectal temperature was significantly (P ≤ 0.05) higher in hens reared in the free-range systems than those housed in the conventional cages. The percentage of hens with mild to severe foot lesions was higher in the free-range system than in the conventional cages. Plumage damages were more common and severe among hens in cages than the free-range hens. No significant difference was recorded for tonic immobility (TI), the number of induction, and the duration of the first head movement during TI. The Fluctuating asymmetry and the weight of immune organs and liver were also not significantly different from each other. The housing of layer hens in the free range systems improved live body weight with a reduction in stress and feather damage. However, it is recommended that further studies should focus on the improvement of the foot lesion-related problems associated with this housing system.
Nevos Melanocíticos Adquiridos: uma Série de 4 Casos
Authors: Oliveira Vivian Bentes de , Nascimento Analu Vieira do , Soares Adnan Saad , Coelho Bruna Kelly Duque , Silva Leimar Pinheiro da , Cabral Lioney Nobre , Pinheiro Tiago Novaes , Vieira Myrian Salles , Vasconcelos II Antônio Jorge Araújo de
Published: August 2023

Introdução: Os nevos melanocíticos adquiridos cutâneos são lesões comuns, começam a aparecer na infância, aumentando em número até a meia-idade, quando sua incidência tende a diminuir. Apresentam-se como pequenas manchas, pápulas ou nódulos, geralmente menores que 6 mm com pigmentação uniforme e bordas lisas, encontradas em locais expostos ao sol. Histopatologicamente, são classificados em nevos juncional, intradérmico ou intramucoso e composto. Objetivo: mostrar uma série de 4 casos clínicos, sendo três nevos melanocíticos intradérmicos e um nevo melanocítico composto, que afetaram três pacientes do sexo feminino e um do sexo masculino, esses buscaram atendimento visando a estética. Material e método: realizado o exame clínico, nos diferentes pacientes, optou-se por remoção cirúrgica completa das lesões, que foram submetidas a avaliação histopatológica para confirmação do diagnóstico clínico. Discussão: a maioria dos pacientes que remove nevos tem como queixa a estética. No entanto, deve ser levado em consideração se a presença destes é prejudicial à função ou se apresenta características de malignidade. Ao planejar a remoção de um nevo, deve-se avaliar as linhas de expressão do paciente, para um bom resultado estético pós-cirúrgico, considerando o tipo de excisão, sutura e cuidados pós-operatórios. Conclusão: Obtivemos resultados similares aos encontrados na literatura, sendo o melhor termo estético desta série de casos a associação da incisão em meia-lua, variação do formato elíptico, com a sutura intradérmica.
Complete purely algebraic proof of the homomorphism between SU(2) and SO(3) without concerning their topological properties
Authors: Khalif Muhammad Ardhi , Amalia Nur Farida
Published: August 2023

The aim of this paper is to provide a complete purely algebraic proof of homo-morphism between SU (2) and SO(3) without concerning the topology of bothgroups. The proof is started by introducing a map ϕ : SU (2) → M L(3, C) de-fined as [ϕ(U )] i j ≡ 12 tr(σ i U σ j U † ). Firstly we proof that the map ϕ satisfies[ϕ(U 1 U 2 )] i j = [ϕ(U 1 )] i k [ϕ(U 2 )] k j , for every U 1 , U 2 ∈ SU (2). The next step is toshow that the collection of ϕ(U ) is having orthogonal property and every ϕ(U ) hasdeterminant of 1. After that, we proof that ϕ(I 2 ) = I 3 . Finally, to make sure thatϕ is indeed a homomorphism, not an isomorphism, we proof that ϕ(−U ) = ϕ(U ),∀U ∈ SU (2).
Scalar fields as dark matter candidates in the modified left-right symmetry model
Authors: Istikomah Istikomah , Isnawati Nurul Embun
Published: August 2023

Dark matter is about 25% of the universe, but its existence is still a mystery. The Modified Left-Right Symmetry Model with the extension of the scalar field, is expected to explain dark matter candidate. The dark matter candidates were analyzed using the Higgs Potential and Lagrangian Yukawa to obtain information on decay and scattering interactions. The generation of dark matter can be determined by analyzing the temperature evolution of the universe, which is divided into three stages post-inflation reheating, symmetry breaking first step, and symmetry breaking second step. The analysis results show that the right-sector scalar field  can be Cold Dark Matter (CDM) candidate because it has non-relativistic characteristics, is stable, does not interact with fermions, and has an abundance of 0.004. The right-sector atom can also be a CDM candidate because it has non-relativistic characteristics, is neutral, and consists of the right nucleons and right electrons. The singlet scalar field  can be the Warm Dark Matter (WDM) candidate because it can decay into fermion, interact in the left and right sectors, is neutrally charged and does not interact with other particles electromagnetically and has an abundance of 0.003. Thus, based on the modified left-right symmetry model, the particle that can be a candidate for dark matter is the scalar field.
Investigation of Biochemical and Microbiological Effects of Prunus mahaleb in Fermented Tea Beverage
Authors: EROĞLU Berfin , DELİK Eda , YILDIRIM Volkan , ÖZÇELİK Aysun , TEFON ÖZTÜRK Burcu Emine
Published: August 2023

Nowadays, fermented beverages such as kombucha are particularly popular among customers because of their health benefits. Although black tea is often used as a substrate for kombucha fermentation, kombucha drinks prepared with various herbal teas are becoming increasingly popular. In this study, the medicinal plant, mahaleb was used for kombucha fermentation. The DPPH method was used to determine the antioxidant activity of kombucha drinks, the Folin–Ciocalteu and aluminium chloride colorimetric method was used to determine the total phenolic and flavonoid content of the drinks, respectively, and the antibacterial activity was determined by the disc diffusion method of the drinks. In addition, the microbiological composition and sensory analysis of the kombucha drinks were investigated. The antioxidant activity of the mahaleb-flavoured kombucha was not statistically different from those of traditional kombucha (p>0.05). As for phenolic content, traditional kombucha had higher content on all fermentation days (p<0.05). The total flavonoid content of mahaleb-flavoured kombucha was similar to traditional kombucha on day 7 of fermentation (p>0.05), but higher than traditional kombucha on day 21 of fermentation (p<0.0.5). In the analysis of the microbiological profile, the highest values of total mesophilic bacteria and acetic acid bacteria content were observed in mahaleb-flavoured kombucha and yeast in traditional kombucha on the 7th and 14th day of fermentation. Mahaleb-flavoured kombucha scored highest on all criteria and was the most popular beverage among participants. This is the first study in which mahaleb was used in kombucha fermentation.
PAUL SINGER EM DEFESA DA ECONOMIA SOLIDÁRIA COMO TRABALHO DECENTE
Authors: Camargo Maria da Penha Lage
Published: August 2023

O escritor Paul Singer teve uma grande contribuição para a sociedade, não só brasileira, mas para todo mundo. Não há possibilidade de citar todos os títulos que escreveu (perto de 170), todavia pretende-se neste artigo discorrer sobre alguns trechos de suas obras que tratam sobre desenvolvimento, capitalismo, globalização, desemprego, exclusão social e a apresentação da economia solidária como possibilidade de combate ao desemprego estrutural e a precarização do trabalho, para ser um modelo que tem como bandeira o trabalho decente, pois este modelo preza pelo ser humano antes do capital. Santos (2018, p.64), conta sobre a trajetória de Singer e de forma suscinta pontuamos alguns dados que ela traz. Na infância/adolescência teve seu primeiro contato com formação socialista por meio dos kibutzim[1] onde via a proximidade da prática de outra economia que mais tarde se materializa na economia solidária, teve militância no sindicato dos metalúrgicos, em partidos políticos (socialista e dos trabalhadores), na universidade, na sociedade civil, no poder público e aquela primeira experiência. O artigo ficou dividido em três blocos: O Capitalismo e os efeitos da Globalização; A Exclusão Social e Economia Solidária como uma solução para o desemprego.
Effect Of Combination Decafeinated Green Tea and Green Coffee In Reducing Cholesterol Levels In Patients With Metabolic Syndrome
Authors: Hazzy Alfata Fandy , Saifur Rohman Mohammad , Astiawati Tri , Tri Tjahjono Cholid , Martini Heny
Published: August 2023

Background: Green tea and green coffee are natural ingredients that improve cholesterol levels. Combining the two in experimental animal studies provides more significant benefits when compared to single administration in reducing cholesterol levels. Objective: This study aimed to determine the effect of decaffeinated green tea and green coffee as adjuvant treatments in reducing blood cholesterol levels. Methods: This randomized controlled trial included 90 metabolic syndrome patients determined according to the IDF criteria for Asian people aged 50–70. All subjects received atorvastatin 20 mg and were divided into three groups. Participants in Group 1 received decaffeinated green tea and green coffee 2.5 grams twice daily, Group 2 received 5 grams daily, and Group 3 received a placebo. The total cholesterol, low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride levels were measured at the beginning and the end of the study. Results: At 90 days, after administration of the extract of decaffeinated green tea and green coffee, we found that the concentration of total cholesterol in Group 1 and Group 2 was significantly reduced compared to the placebo (-50 ± 6.1 vs. -62.8 ± 5.9 vs. -22.5 ± 5.8 mg/dL; p= <0.05). But there was no significant difference in reduction of total cholesterol levels between the first and second groups. The other parameters also decreased, but not significantly compared to the placebo group. Conclusion: Administration of a combination of decaffeinated green tea extract and green coffee as an adjunctive therapy can reduce the average total cholesterol, LDL, HDL, and triglyceride levels more than placebo, but only total cholesterol has a significant difference compared to other cholesterol components.
A 56 Year Old Male with Acute Stent Thrombosis During Percutaneous Coronary Intervention, How to Resolve This Problem?
Authors: Iqda Millisani Hayla , Saifur Rohman Mohammad , Prasetya Indra , Widito Sasmojo
Published: August 2023

Background: Acute stent thrombosis is the complete occlusion of a coronary artery of the previously implanted stent. This unusual complication occurs in percutaneous coronary intervention (PCI), development of myocardial ischemia, and poor prognosis for the patient. After PCI, acute stent thrombosis can occur within 0-24 hours and cause the symptoms like acute coronary syndrome. Incidents of stent thrombosis are about 0.6% to 3.4% for Drug Eluting Stent (DES) implantation, depending on the lesion and patient factors. The etiology of acute stent thrombosis is multifactorial, and early detection can reduce the mortality rate. Case Illustration: A 56 yo male visited Rumah Sakit Saiful Anwar Malang with stable angina pectoris (Class III symptoms with medical therapy) planned for elective cardiac catheterization with routine medical treatment. During PCI, he complained the chest pain, and from cine angiography evaluation showed no flow at the diagonal branch because of the acute thrombosis. Then got thrombosuction and got a white thrombus. After the PCI procedure, he got fibrinolytic with streptokinase 1.5 million units for 60 minutes. He was transferred to CVCU for observation and discharged after five days. Conclusion: Acute stent thrombosis is a severe complication during and after PCI because it is related to high mortality. The mechanisms by which ST arises are complex and multifactorial and must be early detection.
Early Management of Shock Condition in STEMI Patient
Authors: Tria Nugraha Yudha , Anjarwani Setyasih , Satrijo Budi , Saifur Rohman Mohammad
Published: August 2023

Background: Acute myocardial infarction is one of the emerging cardiovascular events worldwide. Infarcts of the inferior wall were present between one-third and half of the patients with RV involvement. The worse outcome was strongly associated with cardiogenic shock, and 7% of cases were caused by RV failure. Objective: This study aimed to describe the diagnosis and management of cardiogenic shock in STEMI Case presentation: A male in his 40s was brought to our hospital 12 hours after the onset of persistent epigastric pain. He had a history of hypertension and a family history of diabetes Mellitus. Diagnostic procedures included blood tests, ECG, X-rays, coronary angiogram, and echocardiography. He underwent PCI to implant DES in his proximal RCA, which had 100% occlusion. The patient was admitted to the intensive cardiovascular care unit for 30 hours and died due to various complications. Conclusion: Current case was very complicated and seriously life-threatening. After acute myocardial infarction, Important problems kept coming up one after the other, and they all affected each other. Patients with cardiogenic shock must be found quickly and treated quickly and aggressively.
Non-Governmental Organizational Factors That Indicate A Project's Success: Case Of Bamenda-Cameroon
Authors: AKUMBOM Paul , Abuengmoh Peter
Published: August 2023

Methods from the field of project management are crucial to the timely and successful creation of cutting-edge technologies and systems. The criteria used to evaluate the success of a project manager's efforts will have varying levels of significance based on the individual's position within the project. This paper set intended to discover what makes NGOs' projects in Bamenda successful. A causal research strategy was used for this investigation. Both descriptive and inferential statistics were used to examine the survey data collected from employees of SIRDEP and CARITAS Bamenda. The structural modelling equation found that public education and involvement positively influenced the outcomes of NGOs' projects in Bamenda. The study's author also demonstrated that the effectiveness of NGOs' projects in Bamenda was bolstered by political influence from inside the country. It was also shown that NGOs in Bamenda benefited from using a project management technique. Conversely, PPM was shown to have a detrimental impact on the project success of NGOs in Bamenda. Analyses of the data also showed that NGOs in Bamenda benefited significantly when their human resource stocks were high. In order to improve the project's chances of success, the research suggests that the project management office or committee place a greater emphasis on community awareness and engagement. The report also suggests that internal political influence be boosted to increase project efficacy and, ultimately, success. The research concludes that a more systematic approach to project management is necessary to raise the success rate of initiatives. Stressing the importance of a well-developed project management approach over the whole project life cycle is essential.
ICT Skills Assessing: A Case of Foundation Training Course Conducted by BARD
Authors: Rahman Kazi  Sonia
Published: August 2023

Skills enabling and ensuring universal access to information have been investigated intensively during the past few years. The general objective of the study was to analyze the need assessment skill of the participants of the Foundation and Special Foundation Course. A total of 272 respondents were finally included in the study from three Foundation Training courses and three Special Foundation Courses using a purposive sampling technique. The research results provide knowledge on ICT skills. Most of the participants have basic ICT knowledge. In some cases such as typing skills, organizing online meetings, developing online questionnaires, MS office applications, networking, and e-Nothi they are not skilled enough to serve their official task smoothly. It is also found from the study among the respondents that physicians are poor in ICT compared to other officials. Most of the participants are not aware of ICT policy and can’t manage ICT work as per policy.
Determinants and Challenges of Green Human Resource Management Practices in Small and Medium Scale Industries
Authors: Shrestha Prakash , Parajuli Dilip , Upadhyay Jitendra  Prasad
Published: August 2023

This paper aims to explore the determinants and challenges associated with green human resource management (GHRM) practices. A snowball sampling approach was used to collect the data from 20 small and medium scale industries in Nepal. 300 workers from the four industrial estates, who work in a range of industries, make up the sample. These workers' viewpoints served as the foundation for this study's analysis. Three stages were involved in gathering these workers' viewpoints. Many factors determine the effective implementation of GHRM practices. The notable determinants include societal contribution, environmental concerns, competitive financial advantage, economic considerations, government pressure, government incentives, community pressure, top management support, market share growth, media relations strategies, public relations strategies, and sustainable policies. However, many potential factors create barriers to the implementation of GHRM practices in their industries. These include the cost of implementing green practices, the complexity and difficulty of adapting green technology, lack of awareness about environmental management, lack of organizational support, lack of managerial interest, employee resistance, and poor level of knowledge. Some other factors such as lack of understanding of green policies, lack of financial gains, lack of support from staff, and high employee turnover also hinder effective practices of GHRM in Nepalese industries. Industries, nowadays, must implement environmentally friendly HR initiatives and practices to ensure the sustainable use of resources, which will increase efficiency, decrease waste, and improve job-related behaviors. To facilitate the effective application of GHRM practices, they must establish a supportive environment.
The Role Of Startup India Seed Fund Scheme (SISFS) & Fund Of Funds For Startups (FFS) In Startups In India
Authors: Jain Meghna
Published: August 2023

Easy availability of capital is very important for the entrepreneurs during the early stages when the enterprise has just begun. There are different sources of funds which could be used by the entrepreneur like venture capital firm or angel investors etc. Funds could be arranged from these funding agents only when the startups have a proof for their concept. Similarly, loans could be provided by banks, but there is a possibility to get from the banks only when the applicants is being backed by assets. It is very important for providing seed funding to the startups who are having an innovative idea for conducting proof of concept trials. Government is not directly funding the startups under Startup India initiative. For providing capital at different stages in the business cycle, Government has implemented Fund of Funds for Startups (FFS) Scheme and Startup India Seed Fund Scheme (SISFS). This study is based on secondary data which is based on Fund of Funds for Startups (FFS) Scheme and Startup India Seed Fund Scheme (SISFS). Data has been analyzed using tables and graphs. The conclusion from the study is that there are many startups in our country and the Government has taken initiatives to provide support to the startups.
Impact of Covid-19 on Globalization and work culture in offices: A Critical Study
Authors: Sharma Sarika , Prakash Surya , Sharma Jay  Shankar
Published: August 2023

The whole world is battling with the mammoth pandemic; COVID-19 has disturbed the work culture as well as global dependencies of economies across the globe and brought it to a standstill. India, a developing middle- lower income country with a massive population of 17.7% of the total world population, ranks second from top after China. This pandemic has led almost all the people of the country to deal with economic, social and emotional costs. An attempt in this study was made to investigate impact of globalization and work culture in offices focusing on understanding the changes caused due to COVID-19 on globalization, as our Hon'ble Prime Minister appeals for ATMANIRBHAR BHARAT and work culture in offices. We find that globalization has been impacted; people made shifts towards the Indian products and services with government also putting ban on various global trades and services. Work culture in offices shifted to work from home, the best alternative for now but faced criticism too; its feasibility would completely depend on the nature of the business/industry. In order to do this, an electronic questionnaire which portrayed answers to the above stated issues was constructed and surveyed. The approach of data collection was primary sources. The financial and psychological consequences of the Covid-19 have been substantial too many people. As businesses went bankrupt, many lost their jobs, and scores of people worldwide dealt with psychological crises of redundancies, isolation, and loneliness.
Innovation and Entrepreneurship Leads to Sustainability and Peace
Authors: Kumar Abhijeet , Kumar Avinash , Kumari Swati , Kumari Neha , Mishra Puja , Behura Ajit Kumar
Published: August 2023

We are starting to understand better what it takes to achieve sustainability and peace, down to the underlying beliefs and behaviours and the incentives that drive people to work toward achieving them. The idea of "Innovation and Entrepreneurship Leads to Sustainability and Peace" is still largely misunderstood and is typically portrayed in a pessimistic light as only the absence of violent conflict. The conventional wisdom holds that we can only successfully nurture and uphold peace and sustainability if we completely understand the complexity of violence, conflict, and sustainability. Since we are not taught anything about peace and sustainability at school, we tend to focus our thoughts on violent conflict and aggressive behaviour rather than on how to end these potentially disastrous behaviour patterns (Coleman, 2012). According to this point of view, a conflict management method known as precluding is implemented to cope with the destructive dynamics of disagreements after they have come into existence. Typically, this is accomplished through a series of speedy, externally-motivated fixes. Eventually, that leads to sustainability at the core of the approach. In order to address the current lack of peace and sustainability in the world, the purpose of this research is to evaluate the concept of prevention from the point of view of conflict resolution rather than conflict avoidance based on innovation and entrepreneurship. The ultimate objective is to reach the end of an agreement over the nature of the actions that need to be taken globally to preserve peace and sustainability. And avoid violence successfully for the prosperity of one and all across the globe, considering The phrase "Vasudhaiva Kutumbakam" means "World is one Family" from Maha Upanishad (Brown, B. 1922) fits the modern global corporate culture.
Perceptions of and Preferences for Telemedicine Use Since the Early Stages of the COVID-19 Pandemic: Cross-Sectional Survey of Patients and Physicians
Authors: Mazouri-Karker Sanae , Lüchinger Robin , Braillard Olivia , Bajwa Nadia , Achab Sophia , Hudelson Patricia , Dominicé Dao Melissa , Junod Perron Noelle
Published: August 2023

Background

While the use of telemedicine (TLM) increased worldwide during the early phases of the COVID-19 pandemic, little is known about the use and acceptance of TLM post the COVID-19 pandemic.

Objective

This study aims to evaluate patients’ and physicians’ self-reported use, preferences, and acceptability of different types of TLM after the initial phases of the COVID-19 pandemic.

Methods

We conducted a cross-sectional survey among patients and physicians in Geneva, Switzerland, between September 2021 and January 2022. Patients in waiting rooms of both private and public medical centers and emergency services were invited to answer a web-based questionnaire. Physicians working in private and public settings were invited by email to answer a similar questionnaire. The questionnaires assessed participants’ sociodemographics and digital literacy; self-reported use of TLM; as well as preferences and acceptability of TLM for different clinical situations.

Results

A total of 567 patients (309/567, 55% women) and 448 physicians (230/448, 51% women and 225/448, 50% in private practice) responded to the questionnaire. Patients (263/567, 46.5%) and physicians (247/448, 55.2%) generally preferred the phone over other TLM formats and considered it to be acceptable for most medical situations. Email (417/567, 73.6% and 308/448, 68.8%) was acceptable for communicating exam results, and medical certificates (327/567, 67.7% and 297/448, 66.2%) and video (302/567, 53.2% and 288/448, 64.3%) was considered acceptable for psychological support by patients and physicians, respectively. Older age was associated with lower acceptability of video for both patients and physicians (odds ratio [OR] 0.03, 95% CI 0.00-0.33 and OR 0.23, 95% CI 0.08-0.66) while previous use of video was positively associated with video acceptability (OR 3.16, 95% CI 1.84-5.43 and OR 3.34, 95% CI 2.91-5.54). Psychiatrists and hospital physicians were more likely to consider video to be acceptable (OR 10.79, 95% CI 3.96-29.30 and OR 3.97, 95% CI 2.23-7.60).

Conclusions

Despite the development of video, the acceptability of video remains lower than that of the phone for most health issues or patient requests. There is a need to better define for which patients and in which medical situations video can become safe and efficient.
Bioanalytical Method Validation of Metformin Hydrochloride in Human Plasma by HPLC-UV for Preliminary Population-Based Pharmacokinetic Modeling Study
Authors: Adhi Pradana Dimas , Kristin Erna , Nugroho Akhmad Kharis , Nugrahaningsih Dwi Aris Agung , Mustofa Mustofa , Wibowo Ari
Published: August 2023

This study aims to validate the method for measuring metformin hydrochloride plasma concentrations using High-Performance Liquid Chromatography (HPLC). This research performed chromatography on a 250 mm 4.6 mm 5 µm purosphere® Star RP-18 column at ambient temperature with a UV detector system at 233 nm. The mobile phase components were 70% phosphate buffer (KH2PO4) (10 mM), sodium dodecyl sulfate (0.3 mM), and 30% acetonitrile. It was pumped at an isocratic flow rate of 1.2 mL/min. Metformin HCl and ranitidine HCl (internal standard) were extracted using acetonitrile. The calibration curve was linear (R2 = 0.9998) in the 0.18–6 µg/mL concentration range. The lower limit of quantification (LLOQ) was 0.18 µg/mL. For intraday accuracy and precision, the percent difference and the coefficient of variation were less than 4 and 7%, and for inter-day were lower than 8 and 6%. The recovery average was 100.96%. The short-term plasma stability test was stable at 24 h at ambient temperature, and the long-term stability test was steady for 30 d at −20 °C. It was also stable after three freeze-thaw cycles. The method meets selectivity, sensitivity, linearity, accuracy, precision, recovery, carryover, and stability requirements and can be applied to population-based pharmacokinetic modeling.
Identification of Volatile Compounds of Oil Palm Flower (Elaeis guineensis Jacq.) with Gas Chromatography and Mass Spectrometry Based on the Difference in Time
Authors: Lubis Fizrul Indra , Sudarjat Sudarjat , Bari Ichsan Nurul , Supratman Unang
Published: August 2023

The pollination process in oil palm is assisted by the insect Elaeidobius kamerunicus, which occurs when male and female flowers bloom producing volatile compounds that act as attractants. This study aims to identify volatile compounds in oil palm flowers based on differences in times with gas chromatography mass spectrometry (GC-MS). The research steps include determining the time of the release of volatile compounds in oil palm flowers, extracted using steam distillation, and identification by GC-MS. There are different times of the release of volatile compounds for each type of oil palm flower. Three times by male flowers, at 08:00 am, 11:00 am and 14:00 pm, with the highest volatile compounds at 14:00 pm. Meanwhile, female flowers occurred at 09:00 am, 12:00 am and 15:00 pm, with the highest volatile compounds at 12:00 am. The results of the GC-MS analysis showed that 21 and 19 volatile compounds were identified, with a total of 38 different types. Estragole compounds were dominant in both types of flowers and did not show significant differences in the area sum values at each time of observation. These results indicated the importance of estragole compound for the pollination process in oil palm.
Triterpenoids from the Stem Bark of Aglaia cucullata (Meliaceae) and Their Cytotoxic Activity against A549 Lung Cancer Cell Line
Authors: Harneti Desi , Mustaqim Iqbal Wahyu , Darwati Darwati , Naini Al Arofatus , Purnama Purnama , Hilmayanti Erina , Mayanti Tri , Nurlelasari Nurlelasari , Gaffar Shabarni , Maharani Rani , Farabi Kindi , Supratman Unang , Fajriah Sofa , Azmi Mohamad Nurul , Shiono Yoshihito
Published: August 2023

The Aglaia species, which contains triterpenoids, is the most numerous in the Meliaceae family. The A. cucullata species, of which there are only a few known examples, has received scant research attention. This investigation aims to identify triterpenoids in an n-hexane preparation of A. cucullata stem bark and evaluate their effects against the A549 lung cancer cell line. Five dammarane-type triterpenoids were isolated from the A. cucullata trunk bark, which is (1) (20S)-20-hydroxydammar-24-en-3-one, (2) cabraleone, (3) cabralealactone, (4) eichlerianic acid, and (5) (+)-fouquierol. Their chemical structures were determined using infrared, high-resolution mass spectrometry, and nuclear magnetic resonance, as well as through data comparison of the reported compounds. Compound 1 was priorly separated from the Aglaia genus, compounds 2–4 were first isolated from the A. cucullata species, and compound 5 has been reportedly isolated from the Meliaceae family and the Aglaia genus. All substances were tested for their lethal potential against the A549 lung cancer cell type. A seco structure in the A ring of dammarane-type triterpenoid might play an important part in the lethal activity of component 4, which showed the greatest activity with an IC50 value of 32.17 µM against the A549 lung cancer cell line.
Improved Mucoadhesive Properties of Repaglinide-Loaded Nanoparticles: Mathematical Modelling through Machine Learning-Based Approach
Authors: Namazi Nader Ibrahim
Published: August 2023

This research work aims to develop a modified repaglinide-loaded chitosan-ethyl cellulose nanoparticles (RPG-ECSNPs) as a novel sustained-release dosage form with improved mucoadhesive properties using an emulsification solvent-evaporation technique. The RPG-ECSNPs with different particle sizes were prepared from various polymers containing ethyl cellulose (EC) as the internal phase and chitosan (CS) as the external phase, and the use of surfactants, including Tween 80 and poloxamer 188 as emulsifiers. In vitro drug release, drug loading amount, and entrapment efficiency have been influenced by changes in the concentrations of CS and EC. The mean droplet size and zeta potential of RPG-ECSNPs were 213 ± 8.5 nm and 16.4 ± 2.4 mV, respectively. The optimized formulation's entrapment efficiency was 66 ± 2.3%, and drug loading was 7.9 ± 1.65%. The release profile was significantly higher in PBS (90%) than in diluted hydrochloric acid (30%) during 24 h of the study. The mucoadhesive function of the particles was examined in vitro using part of rat intestines. The highest adhesive % was observed for the chitosan-coated NPs. No adhesive properties were noticed for chitosan-free NPs (P-value > 0.05). This indicated that ECSNPs can be successfully utilized for sustained and controlled drug delivery of RPG through the GIT.