bluuebunny/crossref_metadata_2025 huggingface dataset:
Psicoterapias breves psicodinâmicas: características da produção científica nacional e estrangeira (1980/2003)
Authors: Yoshida Elisa Medici Pizão , Santeiro Tales Vilela , Santeiro Fabíola Ribeiro de Moraes , Rocha Glaucia Mitsuko Ataka da
Published: October 2015

Apresenta o levantamento de algumas características formais da produção científica para saber quem, onde e o que tem sido indexado nas bases de dados eletrônicas, sob os verbetes: "psicoterapias breves psicodinâmicas" e "psicoterapias psicodinâmicas de tempo limitado". As produções estrangeira e nacional foram cotejadas e críticas apresentadas. A amostra de 534 resumos (1980 a 2003), publicados em bases nacionais e internacionais, indicou que a produção estrangeira foi quantitativamente superior quanto ao número de referências, periódicos científicos e autores. No entanto, a nacional equipara-se em aspectos tais como: média de referência por autor, predomínio de autoria única e adoção de psicoterapias integrativas, em que influências de outras abordagens, que não a psicodinâmica, são identificadas. Nas duas realidades predominaram, ainda, publicações sobre psicoterapias individuais de adultos, veiculadas por periódicos psiquiátricos. Espera-se que com a expansão das bases de dados da psicologia, esta última característica venha a se reverter, ao menos no Brasil.
Verificação da qualidade dos blocos cerâmicos conforme NBR 15270 comercializados em Santa Catarina
Authors: Pilz Silvio Edmundo , Pavan Roberto Carlos , Ritter Mário Gilsone , Cavalheiro Endriana Kirschner , Narciso Matheus Vieira
Published: October 2015

A melhoria da qualidade dos blocos cerâmicos propicia a racionalização da utilização dos recursos naturais e energéticos, a redução de custos, minimizando desperdícios e a ocorrência de manifestações patológicas nas obras, diminuindo esta elevada competitividade. O presente artigo apresenta um resultado da avaliação da conformidade de blocos cerâmicos para alvenaria de vedação, certificados e não certificados, conforme as prescrições da NBR 15.270:2005, comercializadas na região de Chapecó. Os resultados obtidos demonstraram que os 10 fabricantes certificados e não certificados na região de Chapecó – SC, analisados conforme a norma os itens de identificação, características visuais, geométricas, físicas e características mecânicas tem muito que melhorar. Com relação às inspeções visuais, 30% das marcas avaliadas foram rejeitadas no quesito identificação e 70% no quesito características visuais. Quanto às inspeções por ensaios, a porcentagem de marcas rejeitadas quanto às características geométricas foi de 30%. Pode-se observar também que 40% dos blocos produzidos na região de Chapecó ficaram fora do limite normativo no quesito absorção da água, havendo também um grande número de unidades não conformes no quesito resistência mecânica (60% de rejeição), chegando a um resultado de apenas um lote aprovado em todos os quesitos analisados. Isto confirma a necessidade de investimentos em estruturas, tecnologias, técnicas, manuseio e maior grau de fiscalização nos lotes, e principalmente, as empresas compradoras exigirem o mínimo de qualidade, alcançando assim a excelência e otimização da qualidade dos blocos cerâmicos de vedação. Com a melhoria na qualidade do produto final e a total adequação à norma, espera-se que as empresas aumentem a competitividade entre si, fator que beneficia a qualidade do produto consumido e seu consumidor.
3D-BIOPRINTING (Application of 3D printer for Organ Fabrication)
Authors: Aishwarya Y. , Gourangi B. , Abhijeet K.
Published: October 2015

A chronic shortage of human organs for transplantation has become more problematic in spite of major development in transplant technologies. In 2009, only 27,996 (18%) of 154,324 patients received organs and 8,863 (25 per day) died while on the waiting list. As of early 2014, approximately 120,000 people in the U.S. were awaiting an organ transplant.

The solution to this problem is 3D bio-printing. This technology may provide a unique and new opportunity where we can print 3D organs. It incorporates two technologies, tissue engineering, and 3D printing. 3D bioprinting involves dispensing cells onto a biocompatible scaffold using a successive layer-by-layer approach to generate tissue-like three-dimensional structures.

It uses instruction in the CAD file for the formation of the object, high-level computer programming, and the ability to build highly advanced computer systems, it offers hope for bridging the gap between organ shortage and transplantation needs.
IMPACT ANALYSIS OF LAND-COVER (GREENBELTS) CHANGE DUE TO CHANGES IN LAND-USE PLANNING
Authors: Mittal Misha
Published: October 2015

The city and regions, which rely on their ecosystems, depends upon their health and availability. Changes to the usage pattern of these, as a process of urbanization, may bring economically positive impact but can be devastating for the ecology and social well-being of many groups of society. It is thus becoming increasingly important to measure these city resources in order to manage them effectively. The challenge is of appropriate land-use planning giving special consideration to natural systems which combines with the urban edges. This paper briefly analyses the green belt as a component of natural system and its role played in National Capital Region of a developing country (India) as an example. The attempt is made to identify the impacts due to changes in land-use planning on the green belt between two cities. Simultaneously, attention is drawn to the ways and situations, in which other functions can be incorporated within the green belts. These have helped to bring out potentials which can be considered for effective planning of green belt. The study is based on the evidence, case studies and it is suggested that appropriate planning may make green belts (GB) an effective planning tool but monitoring plays the most important role in their performance.
MAPPING WITH THE HELP OF NEW PROPOSED ALGORITHM AND MODIFIED CLUSTER FORMATION ALGORITHM TO RECOMMEND AN ICE CREAM TO THE DIABETIC PATIENT BASED ON SUGAR CONTAIN IN IT
Authors: Gaikwad Suhas Machhindra , Mulay Preeti , Joshi Rahul Raghvendra
Published: October 2015

The research for suggesting an ice cream for a diabetic patient is carried out in data mining by using clustering and mapping between the data for ice cream and diabetic patients. Here, mapping of ice cream dataset with diabetic patient dataset is done by using MFCA, which is proposed and explained in this paper. The results obtained from MCFA algorithm and the new proposed algorithm are explained and verified and it is observed that they are having the relevance.
Medical Images Fusion with Patch Based Structure Tensor
Authors: Luo Fen , Sun Jiangfeng , Hou Shouming
Published: October 2015

Nowadays medical imaging has played an important role in clinical use, which provide important clues for medical diagnosis. In medical image fusion, the extraction of some fine details and description is critical. To solve this problem, a modified structure tensor by considering similarity between two patches is proposed. The patch based filter can suppress noise and add the robustness of the eigen-values of the structure tensor by allowing the use of more information of far away pixels. After defining the new structure tensor, we apply it into medical image fusion with a multi-resolution wavelet theory. The features are extracted and described by the eigen-values of two multi-modality source data. To test the performance of the proposed scheme, the CT and MR images are used as input source images for medical image fusion. The experimental results show that the proposed method can produce better results compared to some related approaches.
Groundwater nanofiltration process efficiency improvement with additional concentrate membrane treatment
Authors: Kukucka Miroslav , Kukucka Nikoleta
Published: October 2015

Nanofiltration (NF) of waste water originated from nanofiltration drinking
water plant stationed in town of Kikinda (Northern Serbia) was investigated.
Experiments on removal characteristics of nanofiltration membranes when
exposed to influent rich in arsenic and natural organic matter under
different flux and transmembrane pressure (TMP) conditions were conducted in
order to obtain drinking water from waste water and reduce total amount of
waste water. Applied NF membranes showed remarkable removal characteristic.
Also, obtained result for concentrate yield, an indicator of reduced
concentrate amount, of 8.89% under optimum flux value presents considerable
amount of reclamated drinking water. Calculated empirical and theoretical
concentration factors quotients were indicated to probable accumulation of
some inlet water components at NF membrane surface. Based on the obtained
results that nanofiltration membranes remove natural organic matter, arsenic,
ammonia and sodium with high efficiencies of 98%, 96%, 80% and 93%
respectively, conceptual design of drinking water plant for City of Kikinda
was defined and presented.
Numerical Prediction Of The Effects Of Miniature Channel Shaped Scratches On The Fracture Behaviour Of Wires For Civil Engineering Applications Using Finite Element Analysis
Authors: Adewole K.K. , Bull S.J.
Published: October 2015

The effects of the miniature channel-shaped scratches not detectable by the present inline electromagnetic defect detection system employed for wires’ surface defect detection on the fracture behaviour of the wires for civil engineering applications were investigated numerically. Finite element analysis revealed that both miniature channel-shaped across-the-thickness and across-the-width scratches change the fracture behaviour of the wires in terms of the fracture initiation locations and fracture process sequence. However, miniature across-the-thickness scratches does not affect the fracture shape of the wire while miniature across-the-width scratches changed the wires’ cup and cone fracture to a fracture shape with a predominantly flat fracture. These results provide an understanding of the fracture behaviour of wires with miniature scratches and serve as an alternative or a complimentary tools to experimental or fractographic failure analysis of wires with miniatures scratches which are difficult to carry out in the laboratory due to the sizes of the scratches.
Assessment Of The Casting Position Factor In Reinforced Concrete Elements In View Of Experimental Studies
Authors: Dybeł Piotr , Furtak Kazimierz
Published: October 2015

The paper presents the results of experimental investigations performed by the authors on the casting position factor. It was proved that at the height of reinforced concrete elements there are different bond conditions. Moreover, the bond depends on concrete mechanical properties, element height as well as concrete mix composition and consistency. The experiments also showed the advisability of determining the casting position factor separately for bars from normal concrete and those from high–performance concrete (HPC). The analysis of investigation results has shown that “good” bond conditions are a relative concept and depend on, among other things, element height. The higher the element the better the concrete to lower bars bond. Consequently, elements of considerable height (higher than 600 mm) demonstrate a bigger difference between concrete to upper bars bond and concrete to lower bars bond.
Dome Over The Gdynia Seaport Building
Authors: Godycki-Ćwirko T. , Nagrodzka-Godycka K. , Piotrkowski P.
Published: October 2015

The paper presents the description of structure and the selected problems of the technical condition, as well as the strength analysis of the thin-walled reinforced concrete shell which has been making a covering of the main hall of the Gdynia Seaport Building through the last 80 years. The rectangle projection of four single curvature shells of the dome was shaped out of mutual perpendicular intersection of two cylindrical shells.

The analysis of the state of stress and deformations was carried out using the special model worked out in MES considering the combination of loads, the thermal ones included. For the long lasting loads (the deadweight of the dome), the computed results of static quantities were confronted with analytical results obtained according to F. Dischinger’s method. This method had been applied by the DYWIDAG Company in Berlin and its branch in Katowice (Poland) who designed the Gdynia Dome.

The computational analysis and the assessment of the technical state, along with laboratory pH tests of concrete, made it possible to carry out the overall evaluation of durability and safety of operation of the Gdynia Seaport Dome through the next decades.
Multipoint Ultrasonic Diagnostics System Of Prestressed T-Beams
Authors: Mariak A. , Wilde K.
Published: October 2015

This paper is devoted to the application of ultrasonic wave propagation phenomena for the diagnostics of prestressed, concrete, bridge T-beams. A multi-point damage detection system is studied with use of numerically obtained data. The system is designed to detect the presence of the material discontinuities as well as their location.
Synthetic G-Quartets as Versatile Nanotools for the Luminescent Detection of G-Quadruplexes
Authors: Laguerre Aurelien , Levillain Marine , Stefan Loic , Haudecoeur Romain , Katranji Fares , Pirrotta Marc , Monchaud David
Published: October 2015

Recent years have witnessed a tremendous increase in the biotechnological applications of nucleic acid-based nanotools. Beyond their biological relevance, nucleobases have indeed found new scopes of applications in bionanotechnology, which are expanding nowadays at an accelerated pace.
Among the four canonical nucleobases (adenine, guanine, cytosine and thymine), guanine is certainly the most useful and used base, thanks to its versatile H-bond donating/accepting properties that make it suitable for being involved in various assemblies ranging from base-pairs to base-quartets.
Here, we would like to report on an innovative guanine-based molecular tool named Tb. Pyro-DOTASQ: this metal complex has a sophisticated chemical structure that allows formation of an intramolecular G-quartet upon interaction with alternative secondary structures known as G-quadruplexes.
This target-promoted molecular switch triggers a luminescence response that would permit the use of Tb. Pyro-DOTASQ to search and detect quadruplex-forming DNA and RNA sequences: its unique design indeed allows it i) to create specific interaction with quadruplexes, ii) to provide an easily
readable luminescent output to monitor this association and iii) to be readily immobilized on graphene surface, thus making Tb. Pyro-DOTASQ a high-value molecular device. Results obtained in the course of in-depth biophysical analyses raise questions about the actual supramolecular structure
of Tb. Pyro-DOTASQ: these results thus shed a bright light on the care that must be exercised when using intricate molecular architectures to construct elaborated supramolecular metal complexes.
Self-assembly of Metallamacrocycles Employing a New Benzil-based Organometallic Bisplatinum(II) Acceptor
Authors: Roy Bijan , Shanmugaraju Sankarasekaran , Saha Rupak , Mukherjee Partha Sarathi
Published: October 2015

A benzil-based semi-rigid dinuclear-organometallic acceptor 4,4'-bis[trans-Pt(PEt3)2(NO3)(ethynyl)]benzil (bisPt-NO3) containing a Pt-ethynyl functionality was synthesized in good yield and characterized by multinuclear NMR (1H,
31P, and 13C), electrospray ionization mass spectrometry (ESI-MS), and single-crystal X-ray diffraction analysis of the iodide analogue bisPt-I. The stoichiometric (1:1) combination of the acceptor bisPt-NO3 separately with four different ditopic
donors (L1–L4; L1 = 9-ethyl-3,6-di(1H-imidazol-1-yl)-9H-carbazole, L2 = 1,4-bis((1H-imidazol-1-yl)methyl)benzene, L3 = 1,3-bis((1H-imidazol-1-yl)methyl)benzene and L4
= 9,10-bis((1H-imidazol-1-yl) methyl)anthracene) yielded four [2 + 2] self-assembled metallacycles M1–M4 in quantitative yields, respectively. All these newly synthesized assemblies were characterized by various spectroscopic techniques (NMR, IR, ESI-MS)
and their sizes/shapes were predicted through geometry optimization employing the PM6 semi-empirical method. The benzil moiety was introduced in the backbone of the acceptor bisPt-NO3 due to the interesting structural feature of long carbonyl C–C bond (?1.54 Å),
which enabled us to probe the role of conformational flexibility on size and shapes of the resulting coordination ensembles.
Seroprevalence and Related Risk Factors of HBsAg, Anti–HCV and Anti–HIV Antibody Among Pregnant Women of Rural India
Authors: Dayal Seema , Singh Amit , Chaturvedi Vineet , Pathak Asha , Gupta Vinay , Jaiswal Shweta
Published: October 2015

BACKGROUND: Vertical transmission is also mode of transmission of HBV, HCV and HIV. Viral infections may cause abortion, ectopic pregnancies and HBV, HCV also causes hepatitis, cirrhosis. ‘Janani Sureksha Yojana’ (safe motherhood program) is a scheme in which pregnant women are benefited if they deliver in government medical facility. Antenatal screening for HBV, HCV and HIV should be done so as to provide appropriate antiviral therapy. The aim of study was to detect the frequency of HBsAg, HCV antibody, HIV antibody and their correlation with risk factors.METHODS: Present study was conducted in central laboratory of Rural Institute of Medical Science and Research Saifai, Etawah (Uttar Pradesh) on pregnant women from 1 January to 31 December 2014.RESULTS: Out of 7867 women, 2.07% were positive for HBsAg, 0.43% and 0.13% for HCV antibody and HIV antibody, respectively. The age group with maximum seropositivity was in 21-30 year (76.44%) and parity with maximum seropositivity was 3-4 children (42.30%). Seropositivity was high among low socio economic status (77.40%). Among the associated risk factors Obstetric and Gynaecology surgeries (46.15%) and blood transfusion (20%) were prominent. These associated risk factors were found more among HBsAg seropositive females (86.66%) and (84.61%) respectively.CONCLUSIONS: The prevalence of HBsAg positive (2.07%) was more. Obstetric and Gynaecology surgery, blood transfusion were major risk factors. So, screening for HBsAg, HCV antibody, HIV antibody should be mandatory for pregnant women to reduce mortality and morbidity.
Screening of New Born Babies for Thyroid Stimulating Hormone, Glucose-6-Phosphate Dehydrogenase, 17-Hydroxyprogesterone and Sickle Cell Disease
Authors: Kalouni Mukunda Raj , Badade Z G , Mohanty Nimain , Bhatta Bhup Dev , Pandey Bhupendra R , Bhatt Rajendra Dev
Published: October 2015

BACKGROUND: The expanded newborn screening programme has now initiated worldwide. Many of the countries around the world made this programme mandatory. The effect of such screening system gives the advantage or betterment to the society as well as the nation.METHODS: Samples were collected from babies aged 48-72 hours by heel prick method in a filter paper provided by Bio-Rad. The written consent was taken from the parents before collecting the blood samples. Blood samples were assayed for TSH and17-OHP by Enzyme Immuno Assay (EIA), G-6-PD was estimated by colorimetric assay provided by Bio-Rad Laboratories, USA and Sickle Cell Disease by sickling testRESULTS: A total of 715 newborns were screened for TSH, G-6-PD, 17-OHP and Sickle cell disease. Out of which 1 neonate found abnormal (increased) thyroid stimulating hormone (1/715), and 8 neonates were G-6-PD deficient (8/715). We did not find any cases of congenital adrenal hyperplasia and sickle cell disease.CONCLUSIONS: In this study the prevalence of Congenital Hypothyroidism and Glucose-6-Phosphate dehydrogenase deficiency was found to be 1:715 and 1:89 respectively. No cases of congenital adrenal hyperplasia and sickle cell disease were found.
Research Misconduct: The Cardinal Sin
Authors: Risal Prabodh
Published: October 2015

Research misconduct, a sinful act has to be addressed properly on time to prevent its consequences. Initially, we need to know burden and contributing factors of research misconduct in Nepal. Then it could be minimized by effective measures like increasing awareness through proper training and workshops. One can also encourage peers to speak up against the act of misconduct done by the colleagues in their respective field or institution.
Results of wrist extension reconstruction in C5–8 brachial plexus palsy by transferring the pronator quadratus motor branch to the extensor carpi radialis brevis muscle
Authors: Bertelli Jayme Augusto , Ghizoni Marcos Flávio , Tacca Cristiano Paulo
Published: October 2015

OBJECT

The objective of this study was to report the results of pronator quadratus (PQ) motor branch transfers to the extensor carpi radialis brevis (ECRB) motor branch to reconstruct wrist extension in C5–8 root lesions of the brachial plexus.

METHODS

Twenty-eight patients, averaging 24 years of age, with C5–8 root injuries underwent operations an average of 7 months after their accident. In 19 patients, wrist extension was impossible at baseline, whereas in 9 patients wrist extension was managed by activating thumb and wrist extensors. When these 9 patients grasped an object, their wrist dropped and grasp strength was lost. Wrist extension was reconstructed by transferring the PQ motor to the ECRB motor branch. After surgery, patients were followed for at least 12 months, with final follow-up an average of 22 months after surgery.

RESULTS

Successful reinnervation of the ECRB was demonstrated in 27 of the 28 patients. In 25 of the patients, wrist extension scored M4, and in 2 it scored M3.

CONCLUSIONS

In C5–8 root injuries, wrist extension can be predictably reconstructed by transferring the PQ motor branch to reinnervate the ECRB.
Building an electronic health record integrated quality of life outcomes registry for spine surgery
Authors: Azad Tej D. , Kalani Maziyar , Wolf Terrill , Kearney Alisa , Lee Yohan , Flannery Lisa , Chen David , Berroya Ryan , Eisenberg Matthew , Park Jon , Shuer Lawrence , Kerr Alison , Ratliff John K.
Published: October 2015

OBJECT

Demonstrating the value of spine care requires adequate outcomes assessment. Long-term outcomes are best measured as overall improvement in quality of life (QOL) after surgical intervention. Present registries often require parallel data entry, introducing inefficiencies and limiting compliance. The authors detail the methodology of constructing an integrated electronic health record (EHR) system to collect QOL metrics and demonstrate the effect of data collection on routine clinical workflow. A streamlined approach to collecting QOL data can capture patient data without requiring dual data entry and without increasing clinic visit times.

METHODS

Through extensive literature review, a combination of QOL assessments was selected, consisting of the Patient Health Questionnaire-2 and -9, Oswestry Disability Index, Neck Disability Index, and visual analog scale for pain. These metrics were used to provide assessment of QOL following spine surgery and were incorporated into standard clinic workflow by a multidisciplinary team of surgeons, advanced practice providers, and health care information technology specialists. A clinical dashboard tracking more than 25 patient variables was developed. Clinic flow was assessed and opportunities for improvement reviewed. Duration of clinic visits before and after initiation of QOL measure capture was recorded, with assessment of mean clinic visit times for the 12 months before and the 12 months after implementation.

RESULTS

The integrated QOL capture was instituted for 3 spine surgeons in a tertiary care academic center. In the 12-month period prior to initiating collection of QOL data, 806 new patient visits were completed with an average visit time of 127.9 ± 51.5 minutes. In the 12 months after implementation, 1013 new patient visits were recorded, with 791 providing QOL measures with an average visit time of 117.0 ± 45.7 minutes. Initially the primary means of collecting patient outcome data was via paper form, with gradual transition to collection via entry into the electronic medical records system. To improve electronic data capture, paper forms were eliminated and an online portal used as part of the patient rooming process. This improved electronic capture to nearly 98% without decreasing the number of patients enrolled in the process.

CONCLUSIONS

A systematic approach to collecting spine-related QOL data within an EHR system is feasible and offers distinct advantages over registries that require dual data entry. The process of data collection does not impact patients’ clinical visit or providers’ clinical workflow. This approach is scalable, and may form the foundation for a decentralized outcomes registry network.
Endoscopic fenestration of intraventricular cerebrospinal fluid cysts: the contralateral approach
Authors: Hugelshofer Michael , Koechlin Nicolas Olmo , Marcus Hani J. , Kockro Ralf A. , Reisch Robert
Published: October 2015

OBJECT

The endoscopic fenestration of intraventricular CSF cysts has evolved into a well-accepted treatment modality. However, definition of the optimal trajectory for endoscopic fenestration may be difficult. Distorted ventricular anatomy and poor visibility within the cyst due to its contents can make endoscopic fenestration challenging if approached from the ipsilateral side. In addition, transcortical approaches can theoretically cause injury to eloquent cortex, particularly in patients with dominant-sided lesions. The aim of this study was to examine the value of the contralateral transcortical transventricular approach in patients with dominant-sided ventricular cysts.

METHODS

During a 5-year period between 2007 and 2011, 31 patients with intraventricular CSF cysts underwent surgery by the senior author (R.R.). Fourteen of these patients had cysts located on the dominant side. An image-guided endoscopic cyst fenestration via the contralateral transcortical transventricular approach was performed in 11 patients. A retrospective chart review was performed in all these patients to extract data on clinical presentation, operative technique, and surgical outcome.

RESULTS

The most common presenting symptom was headache, followed by memory deficits and cognitive deterioration. In all cases CSF cysts were space occupying, with associated obstructive hydrocephalus in 8 patients. Image-guided endoscopic fenestration was successfully performed in all cases, with septum pellucidotomy necessary in 6 cases, and endoscopic third ventriculostomy in 1 case for additional aqueductal occlusion. Postoperative clinical outcome was excellent, with no associated permanent neurological or neuropsychological morbidity. No recurrent cysts were observed over a mean follow-up period of 2 years and 3 months.

CONCLUSIONS

The contralateral approach to ventricular cysts can achieve excellent surgical outcomes while minimizing approach-related trauma to the dominant hemisphere. Careful case selection is essential to ensure that the contralateral endoscopic trajectory is the best possible exposure for sufficient cyst fenestration and restoration of CSF circulation.
Assessment of Energy Intake and Energy Expenditure of Male Adolescent Academy-Level Soccer Players during a Competitive Week
Authors: Briggs Marc , Cockburn Emma , Rumbold Penny , Rae Glen , Stevenson Emma , Russell Mark
Published: October 2015

This study investigated the energy intake and expenditure of professional adolescent academy-level soccer players during a competitive week. Over a seven day period that included four training days, two rest days and a match day, energy intake (self-reported weighed food diary and 24-h recall) and expenditure (tri-axial accelerometry) were recorded in 10 male players from a professional English Premier League club. The mean macronutrient composition of the dietary intake was 318 ± 24 g·day−1 (5.6 ± 0.4 g·kg−1 BM) carbohydrate, 86 ± 10 g·day−1 (1.5 ± 0.2 g·kg−1 BM) protein and 70 ± 7 g·day−1 (1.2 ± 0.1 g·kg−1 BM) fats, representing 55% ± 3%, 16% ± 1%, and 29% ± 2% of mean daily energy intake respectively. A mean daily energy deficit of −1302 ± 1662 kJ (p = 0.035) was observed between energy intake (9395 ± 1344 kJ) and energy expenditure (10679 ± 1026 kJ). Match days (−2278 ± 2307 kJ, p = 0.012) and heavy training days (−2114 ± 2257 kJ, p = 0.016) elicited the greatest deficits between intake and expenditure. In conclusion, the mean daily energy intake of professional adolescent academy-level soccer players was lower than the energy expended during a competitive week. The magnitudes of these deficits were greatest on match and heavy training days. These findings may have both short and long term implications on the performance and physical development of adolescent soccer players.
Adaptive Designs with Discrete Test Statistics and Consideration of Overrunning
Authors: Burkhardt B. , Faldum A. , Schmidt R.
Published: October 2015

Background: Interim analyses are used in clinical trials in order to enable early decisions for medical, ethical, and economic reasons. However, it appears unfeasible to stop a trial during such an interim analysis. New patients will thus enter the trial while the interim analysis is ongoing. Moreover, depending on the event kinetics of the specific disease, the trial design, and the corresponding endpoints, some patients might still be unevaluable at the interim analysis due to not yet completed follow-up. Occur-rence of these types of patients is characteristic for sequentially analyzed trials. Such patients are referred to as interim patients. In trials with multiple primary endpoints, another type of interim patients occurs. If some but not all null hypotheses can be rejected at the interim analysis, the trial might be continued to a second stage in order to answer the remaining questions. These second stage patients, however, provide new data to all trial questions including the already rejected ones and thus formally act as interim patients regarding the already rejected null hypotheses. Although all kinds of interim patients are not part of the interim analysis, the data collected on those patients have to be sent to the office of regulatory affairs and will be analyzed. If a smaller or contrasting treatment effect is observed in interim patients, this might lead to a withdrawal of an earlier superiority proof.

Objectives: Presently, interim patients and their data are usually not considered in the confirmatory test. We offer a strategy to deal with interim patients in sequentially analyzed trials with discrete test statistics. The method covers sequentially analyzed single-and multi-arm trials with one or multiple primary endpoints.

Methods: When planning adaptive designs, it is common practice to assume that the stage-wise p-values are independent and standard uniformly distributed under the null hypothesis. In the context of discrete test statistics, this implies conservative tests. We provide an algorithm which iteratively optimizes an initially given design while adjusting for both discreteness of test statistics and interim patients. The algorithm is described verbally, graphically and formally to facilitate immediate implementation in computer software.

Results: The optimized design exploits the aspired significance level better and is more powerful than the initial one. The algorithm applies to fixed sample and planned flexible adaptive designs for single- and multi-arm trials with one or multiple primary endpoints. The benefit increases with the number of interim patients.

Conclusions: When planning a trial with interim analyses, the rules for decisions must be adjusted to interim patients. Otherwise, the test procedure is conservative resulting in loss of power. This is essential in situations where the number of interim patients is important compared to the first stage, particularly in trials with multiple primary endpoints.
What is Most Important in Transferring Goodwill from Charity Run Participants to Sponsors?
Authors: Smith Wayne W. , Pitts Robert E. , Wang Weishen , Mack Rhonda W.
Published: October 2015

This study examines whether event factors (satisfaction with the event, attitudes towards the event, and attitudes toward the activity) or program factors (sponsor fit and perceptions of corporate citizenship) are the most influential in shaping participants' attitudes towards sponsors.
Structural Equation Modeling was applied to data from an annual charitable run located in the southeastern US. Results indicate that the quality of the event was a secondary factor in determining brand equity transference between sponsors and participants as measured by attitude toward the
sponsors. Perceptions of corporate citizenship and sponsor fit were the most influential factors in transference. Overall this study addresses the need to examine local and smaller events and sponsorship effects.
Factors Determining Attendance at a Film Festival
Authors: Devesa María , Báez Andrea , Figueroa Víctor , Herrero Luis César
Published: October 2015

The goal of this article is to assess which factors determine consumption of a cultural festival. Drawing on the data obtained from a survey among attendees of the Valdivia International Film Festival (Chile), two models analyzing consumption intensity (number of films seen) and participation frequency (number of editions attended) are estimated. The variables included in the models reflect the sociodemographic features of those attending as well as specific factors linked to experience and previous cultural consumption, in addition to variables related to motivation. Findings show the most important variables are those related to cultural capital when accounting for participation in the event, although age and place of residence in the case of participation frequency also prove significant. Certain implications regarding cultural policy and management are drawn from the findings to emerge.
Patient Acceptability of the Yorkshire Dialysis Decision AID (YODDA) Booklet: A Prospective Non-Randomized Comparison Study across 6 Predialysis Services
Authors: Winterbottom Anna E. , Gavaruzzi Teresa , Mooney Andrew , Wilkie Martin , Davies Simon J. , Crane Dennis , Tupling Ken , Baxter Paul D. , Meads David M. , Mathers Nigel , Bekker Hilary L.
Published: October 2015

Background

Patients are satisfied with their kidney care but want more support in making dialysis choices. Predialysis leaflets vary across services, with few being sufficient to enable patients’ informed decision making. We describe the acceptability of a patient decision aid and feasibility of evaluating its effectiveness within usual predialysis practice.

Methods

Prospective non-randomized comparison design, Usual Care or Usual Care Plus Yorkshire Dialysis Decision Aid Booklet (+YoDDA), in 6 referral centers (Yorkshire-Humber, UK) for patients with sustained deterioration of kidney function. Consenting (C) patients completed questionnaires after predialysis consultation (T1), and 6 weeks later (T2). Measures assessed YoDDA's utility to support patients’ decisions and integration within usual care.

Results

Usual Care ( n = 105) and +YoDDA ( n = 84) participant characteristics were similar: male (62%), white (94%), age (mean = 62.6; standard deviation [SD] 14.4), kidney disease severity (glomerular filtration rate [eGFR] mean = 14.7; SD 3.7); decisional conflict was < 25; choice-preference for home versus hospital dialysis approximately 50:50. Patients valued receiving YoDDA, reading it on their own (96%), and sharing it with family (72%). The +YoDDA participants had higher scores for understanding kidney disease, reasoning about options, feeling in control, sharing their decision with family. Study engagement varied by center (estimated range 14 – 49%; mean 45%); participants varied in completion of decision quality measures.

Conclusions

Receiving YoDDA as part of predialysis education was valued and useful to patients with worsening kidney disease. Integrating YoDDA actively within predialysis programs will meet clinical guidelines and patient need to support dialysis decision making in the context of patients’ lifestyle.
Influence of bulky yet flexible N-heterocyclic carbene ligands in gold catalysis
Authors: Collado Alba , Patrick Scott R , Gasperini Danila , Meiries Sebastien , Nolan Steven P
Published: October 2015

Three new Au(I) complexes of the formula [Au(NHC)(NTf2)] (NHC = N-heterocyclic carbene) bearing bulky and flexible ligands have been synthesised. The ligands studied are IPent, IHept and INon which belong to the ‘ITent’ (‘Tent’ for ‘tentacular’) family of NHC derivatives. The effect of these ligands in gold-promoted transformations has been investigated.
NON-LINEAR MINI-MAX PROBLEM OF MULTI-STOP FLIGHT ROUTES
Authors: Krile Srećko , Krile Marina , Průša Petr
Published: October 2015

The major change in trends of air transport development is to increase operating efficiency, productivity and profitability. Airline companies (air operators or carriers) can ensure significant fuel savings and better utilization of airplanes capacity. So they need better transport planning tool for costs minimization on a voyage route with multiple loading/unloading airports (multi-stop routes).The existing routes can be re-optimized (improved) or alternative routes can be offered instead. In this research the efficient heuristic algorithm for optimal transportation of N different loads (e.g. passenger contingent) for the airplane with limited capacity is being developed. The main goal of algorithm is to reduce the idle capacity on the route, to decrease expenses and to increase revenue. Through many test examples we can see that such approach functions very good and calculation complexity is under control.
SMART AND SUSTAINABLE TRANSPORT: SHORT REVIEW OF THE SPECIAL ISSUE
Authors: Gopalakrishnan Kasthurirangan , Chitturi Madhav V. , Prentkovskis Olegas
Published: October 2015

„Smart and sustainable transport: short review of the special issue" Transport, 30(3), p. 243-246
Dino del Garbo et le pouvoir de l’imagination sur le corps
Authors: Robert Aurélien
Published: October 2015

Dino del Garbo, médecin actif dans les premières décennies du xiv e siècle, est surtout connu pour son commentaire au poème de Guido Cavalcanti Donna me prega . La présente étude propose l’édition d’une question quodlibétique sur la capacité de l’imagination à altérer le corps, disputée à Bologne ou Sienne dans les années 1320. Nous examinons le contexte médical et philosophique dans lequel s’inscrit cette question, en montrant notamment comment le débat s’est progressivement cristallisé autour de l’opposition entre un modèle avicennien et un modèle aristotélicien des rapports entre l’âme et le corps. L’analyse de ce débat permet d’éclairer d’un jour nouveau la glose de Dino del Garbo à Donna me prega et aussi, de manière incidente, le poème lui-même.
Baseline Indicators and Implementation Strategies in a Statewide Correctional Nurse Competencies Program: Mid-Year Report
Authors: Shelton Deborah , Reagan Louise , Weiskopf Constance , Panosky Denise , Nicholson Michael , Diaz Desiree
Published: October 2015

Background:

This 3-year, public–academic workforce development project aimed to establish indicators for quality correctional nursing care to empirically test the translation of correctional nursing standards into practical and applied competencies.

Method:

Approaches to document indicators and achieve implementation of a correctional nurse competency system include (a) knowledge transfer and exchange, (b) system mapping, (c) adherence to implementation plan and strategy, and (d) practice-based action research.

Results:

Indicators were established. Twenty-five percent (
n
= 111) of nurses maintained clinical credentials beyond the basic requirements; 86% (
n
= 381) of nurses received continuing nursing education certificates, 98% (
n
= 434) of nurses were satisfied with the program, and 43% (
n
= 9,052) of inmate/patients were satisfied with clinical care. Quality ratings of program educators averaged 4.79 on a 5-point scale.

Conclusion:

Innovation is supported by adding continuous improvement components to the implementation of a correctional nurse competency system effort. Team members’ consensus decision making enabled them to apply their domain-specific knowledge to assess the success of the implementation strategy.

J Contin Educ Nurs.
2015;46(10):455–461.
Engaging Clinical Nurses in Quality Improvement Projects
Authors: Moore Susan , Stichler Jaynelle F.
Published: October 2015

Clinical nurses have the knowledge and expertise required to provide efficient and proficient patient care. Time and knowledge deficits can prevent nurses from developing and implementing quality improvement or evidence-based practice projects. This article reviews a process for professional development of clinical nurses that helped them to define, implement, and analyze quality improvement or evidence-based practice projects. The purpose of this project was to educate advanced clinical nurses to manage a change project from inception to completion, using the Six Sigma DMAIC (
D
efine,
M
easure,
A
nalyze,
I
mprove,
C
ontrol) Change Acceleration Process as a framework. One-to-one mentoring and didactic in-services advanced the knowledge, appreciation, and practice of advanced practice clinicians who completed multiple change projects. The projects facilitated clinical practice changes, with improved patient outcomes; a unit cultural shift, with appreciation of quality improvement and evidence-based projects; and engagement with colleagues. Project outcomes were displayed in poster presentations at a hospital exposition for knowledge dissemination.

J Contin Educ Nurs.
2015;46(10):470–476.
Current Antidepressant Therapy: A Critical Examination
Authors: Mori Neil , Lockwood Laura , McCall W. Vaughn
Published: October 2015

Depression remains a major health problem, resulting in an annual economic burden in the hundreds of billions of dollars. This article reviews the limitations of current treatments for depression, including first-line therapies as well as methods used for treatment-refractory depression (TRD). Antidepressant medication remains the most common method of therapy, yet, compared to medications for nonpsychiatric conditions, antidepressants have a relatively low response rate, high relapse rate, and long time to response, as well as side effects that limit tolerability or contribute to poor compliance. Furthermore, there is no definitive algorithm in place or method to ascertain what pharmacologic options will be the most effective for a patient, regardless of whether they are treatment-naïve or have TRD. Electro-convulsive therapy (ECT) remains an effective option for TRD but is limited by availability and risks of short-term cognitive impairment. Although better tolerated, current data suggest newer neurostimulation therapies have yet to offer anything as efficacious as ECT or more convenient than antidepressant medication. Although psychotherapy is often recommended as a first-line option, there are many actual and perceived barriers in today’s society that prevent its use when indicated. Factors that hinder effective treatment common to all modalities include cost, public and individual stigma, inconsistent measuring of illness severity and treatment response, and limited knowledge of the genetic variances among patients. The authors of this article conclude that more novel approaches to treatment must be investigated in the hopes of finding solutions that can overcome these barriers.

[
Psychiatr Ann
. 2015;45(9):456–462.]
Ophthalmological Findings of Turkish Children With Muscular Dystrophies
Authors: Ozer Pinar Altiaylik , Kabatas Emrah Utku , Ertugrul Gokce Tasdemir , Kurtul Bengi Ece , Aksoy Ayse , Yuksel Deniz , Ozkan Mehpare
Published: October 2015

Purpose:

To present the results of ophthalmological examinations in children with muscular dystrophies and highlight the importance of their ophthalmological evaluation.

Methods:

Retrospective analysis of the ophthalmological examination records in 74 children with a type of muscular dystrophy, examined between January 2011 and January 2015, was performed.

Results:

The most common type of muscular dystrophy observed in our patients was Duchenne muscular dystrophy (67.5%), followed by Becker muscular dystrophy (9.4%), myotonic dystrophy (8%), limb-girdle muscular dystrophy (6.7%), merosin-negative muscular dystrophy (4%), and Ullrich muscular dystrophy (4%). Ten cases of Duchenne muscular dystrophy had both macular and retinal pigmentary changes (20%) and 9 had abnormal electroretinographies with decreased photopic and scotopic responses. Ptosis was the most common finding (83.3%). No abnormalities of light reflexes, pupil size, or saccadic and smooth pursuit movements were seen among cases with myotonic dystrophy.

Conclusions:

Ophthalmological problems are commonly seen in children with muscular dystrophies. Simple ophthalmological screening and early intervention can improve their communication skills by way of increasing their visual talents.

[
J Pediatr Ophthalmol Strabismus.
2015;52(5):311–316.]
Mechanism of Action for Nonpharmacological Therapies for Individuals With Dementia: Implications for Practice and Research
Authors: Burgener Sandy C. , Jao Ying-Ling , Anderson Joel G. , Bossen Ann L.
Published: October 2015

The current review addresses the need for increased use of evidence-based, nonpharmacological therapies for individuals with dementia. To facilitate understanding of the potential efficacy of nonpharmacological therapies on cognitive functioning for individuals with dementia, the mechanisms of action for selected therapies are described, including the assessment method used to identify the mechanism. The strength of evidence supporting each therapy was evaluated, with some therapies demonstrating strong support and others only moderate support for their effectiveness and mechanism of action. Therapies with the strongest support include (a) cognitive training/stimulation, (b) physical exercise, and (c) music. Therapies with moderate support include (a) biofield, (b) meditation, (c) engagement with a naturally restorative environment, and (d) social engagement. Although the strength of evidence varies, together these therapies offer treatments designed to improve cognitive functioning, have low risks and adverse effects, and have the potential for widespread accessibility, thereby increasing the potential range of therapies for individuals with dementia.
[Res Gerontol Nurs. 2015; 8(5):240–259.]
The Characteristics and Short-term Refractive Error Outcomes of Cystoid Macular Edema in Premature Neonates as Detected by Spectral-Domain Optical Coherence Tomography
Authors: Bondalapati Sailaja , Milam Ronald W. , Ulrich J. Niklas , Cabrera Michelle T.
Published: October 2015

BACKGROUND AND OBJECTIVE:

To explore characteristics associated with cystoid macular edema (CME) in neonates screened for retinopathy of prematurity (ROP).

PATIENTS AND METHODS:

In this institutional review board-approved, prospective, observational study, premature neonates underwent imaging with handheld spectral-domain optical coherence tomography.

RESULTS:

Of 73 included infants (median gestational age [GA]: 28 weeks, range 23–33 weeks; birth weight: 966 g, range 506 g – 1695 g), 28 (38%) had CME and 17/28 (61%) had ROP. CME was associated with ROP (
P
= .03) and younger GA (
P
= .04), but not associated with sex, race, birth weight, postmenstrual age at imaging, ROP severity, or myopia at median 6 months corrected age. CME resolved in three cases after bevacizumab treatment for type 1 ROP and in five cases without treatment. CME appeared in two cases several weeks following injections.

CONCLUSION:

CME was associated with ROP and younger GA, but not with myopia. Intravitreal bevacizumab for type 1 ROP has inconclusive effects on CME.

[
Ophthalmic Surg Lasers Imaging Retina
. 2015;46:806–812.]