bluuebunny/crossref_metadata_2025 huggingface dataset:
ENDOCARDITE INFECCIOSA
Authors:   Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP. Unidade Clínica de Valvopatias,, Cordeiro Fernandes João Ricardo , Pezzute Lopes Mariana ,   Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP. Unidade Clínica de Valvopatias,, Focaccia Siciliano Rinaldo ,   Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP. Unidade Clínica de Valvopatias,, Tavares Veronese Elinthon ,   Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP. Unidade Clínica de Valvopatias,
Published: July 2022

A incidência de endocardite infecciosa (EI) vem aumentando progressivamente, especialmente na população idosa. A apresentação pode ser aguda ou subaguda/crônica, podendo ter evolução fatal se não tratada agressivamente. Em geral, acomete pacientes com alterações estruturais cardíacas (doença reumática, cardiopatias congê-nitas, cirurgia cardíaca valvar prévia), além daqueles portadores de cateteres de longa permanência ou dispositivos intracardíacos e expostos a condições que possam gerar bacteremia, como tratamentos dentários, procedimentos invasivos em trato genitourinário ou intestinal e uso de drogas ilícitas endovenosas. Os principais microorganismos que causam EI são estafilococos e estreptococos. Nos casos de infecção por Staphylococ-cus aureus, ocorre progressão clínica mais rápida, e há maior chance de septicemia e destruição da anatomia valvar com formação de abscessos perivalvares e embolias sépticas. Por outro lado, estreptococos, especialmente do grupo viridans, causam geralmente infecções com evolução mais arrastada. Os dois pilares do diagnóstico da EI consistem nas hemoculturas e no ecocardiograma. Outros exames de imagem como a tomografia por emissão de pósitrons (PET-CT) podem auxiliar no diagnóstico, sobretudo em casos de EI de próteses valvares. O tratamento medicamentoso deve ser administrado prioritariamente por via endovenosa e com antibióticos de elevada atividade bactericida. A finalidade do tratamento cirúrgico é remover o tecido infectado e restaurar a função valvar. A indicação cirúrgica ocorre em casos de insuficiência cardíaca refratária, evidência de falência clínica do tratamento antibiótico, presença de abscesso ou fístula, novo evento embólico, além de EI causada por organismos de maior virulência, tais como fungos.
Antroponímia em Libras: análise de sinais-nome atribuídos por surdos
Authors: Sousa Alexandre Melo de , Menezes Ketlen Cristina dos Santos Oliveira
Published: July 2022

No campo dos estudos do léxico, a Antroponímia (uma das subáreas da Onomástica) se dedica ao estudo dos nomes próprios de pessoas. Embora haja inúmeros trabalhos antroponímicos em línguas orais no Brasil, ainda são poucos os estudos com foco nas línguas de sinais. O presente artigo tem como objetivo analisar os sinais em Libras que nomeiam acadêmicos ouvintes do curso de Letras-Libras da Universidade Federal do Acre. Os dados foram coletados por meio de entrevistas filmadas entre os anos de 2020 e 2021. A análise segue a proposta de Barros (2018), que considera três grupos de aspectos motivacionais: Aspecto Físico (AF), Aspecto Comportamental (AC) e Empréstimo da Língua Oral (ELO). Os resultados foram quantificados e revelaram que, dos sinais coletados, 55% são motivados por AF; 35% por ELO + AF; 5%, por AF + AC; e 5%, por AC + AF. Quanto ao contexto de batismo, 75% dos entrevistados informaram que seus batismos foram coletivos e 25% foram individuais.
PENDAMPINGAN PELAKU USAHA DEGAN SOSIALISASI BRANDING, MARKETING DAN SERTIFIKASI HALAL
Authors: Susono Susono  , Kevin Muhammad Benna Rivo  , Faridha Rahmawati  , Lestari Dini Pratiwi  , Edi Ariyanto  , Indah Choirunnisa  , Yusuf Alam Mahdiyan  , Eliya Ayun Melani  , Rahma Dani  , Heny Yustina
Published: July 2022

Usaha Mikro Kecil Menengah (UMKM) merupakan kegiatan usaha yang mampu memperluas lapangan kerja. Memberikan pelayaan ekonomi  secara luas kepada masyarakat Desa Igirmranak, berperan dalam proses peningkatan pendapatan masyrakat, mendorong pertumbuhan ekonomi, dan berberan dalam mewujudkan stabilitas nasional.

Usaha Mikro Kecil Menengah (UMKM) Desa Igirmranak, Kec. Kajajar, Kab. Wonosobo dalam memproduksi, manisan carica, selai carica, sirup terong belanda dan dodol terong belanda mengunakan alat produksi yang sederhana serta pendidikan SDM pelaku UKM masih rendah namun tetap menghasilkan produk yang berkualitas, segi kualitas produk UKM sudah bagus, namun perlu peningkatan. Segi nilai: harga produk UKM yang dihasilakn mampu diterima oleh masyarakat, UKM bisa melalukan promosi melalui pameran dan internet atau marketplace. Sebagian UKM di Desa Igirmranak belum mempunyai brading, sertifikasi halal dan hakpaten.
PENYULUHAN KESEHATAN REPRODUKSI KELUARGA SEBAGAI UPAYA PENINGKATAN KUALITAS HIDUP
Authors: Musdalifah  , Yuliana  , Safriadi Darmansyah
Published: July 2022

Kesehatan reproduksi keluarga diwarnai oleh pertumbuhan, perubahan, munculnya berbagai kesempatan, dan sering sekali menghadapi resiko kesehatan reproduksi. Keterbatasan akses informasi bagi remaja Indonesia mengenai kesehatan reproduksi terjadi karena masyarakat beranggapan bahwa seksualitas adalah hal yang tabu. Sehingga sedikit remaja yang memperoleh informasi mengenai kesehatan reproduksi terutama pendidikan seks dari orangtuanya. Kegiatan sosialisasi dilaksanakan pada hari Jumat, tanggal 16 Februari 2022 pada pukul 09.00 Wita bertempat di lombang-lombang wilayah kerja puskesmas tampa padang kelurahan sinyonyoi kec.kalukku kab.mamuju. Kegiatan ini bertujuan untuk memberikan informasi kepada masyarakat tentang pentingnya menjaga kesehatan reproduksi dalam meningkatkan kualitas hidup. Proses edukasi ini menggunakan metode ceramah dengan bantuan powerpoint dan leaflet.

Hasil yang diperoleh dari kegiatan ini adalah remaja peserta kegiatan pengabdian ini menjadi lebih paham dan lebih tahu tentang bagaimana cara meningkatkan kualitas hidup khususnya dimasa pandemic ini. Penilaian tersebut didasarkan atas respon dan antusiasme peserta dalam menerima materi yang diberikan. Termasuk respon positif peserta dalam menjawab pertanyaan secara benar ketika diberikan pertanyaan oleh pemateri.
Plasmodynamic synthesis of metal oxides in a carbon dioxide environment on the example of systems Ti – O and Fe – O
Authors:   Institute of environmental and agricultural biology (X-BiO), Tyumen State University, Shanenkov I. I. ,   School of Energy and Power Engineering, Tomsk Polytechnic University, Sivkov А. А. ,   School of Energy and Power Engineering, Tomsk Polytechnic University, Tsimmerman А. I. ,   Institute of environmental and agricultural biology (X-BiO), Tyumen State University,   School of Energy and Power Engineering, Tomsk Polytechnic University, Nikitin D. S. ,   Institute of environmental and agricultural biology (X-BiO), Tyumen State University,   School of Energy and Power Engineering, Tomsk Polytechnic University, Tabakaev R. B. ,   Institute of environmental and agricultural biology (X-BiO), Tyumen State University,   School of Energy and Power Engineering, Tomsk Polytechnic University
Published: July 2022

The issues of decarbonization, which have recently received increased attention from the world community, mainly due to global warming, require the search for new solutions related to the utilization of carbon dioxide. The main problem of carbon dioxide conversion is the need to overcome the high stability of its molecules that requires the supply of a significant amount of energy. This paper presents the experimental results on the high-energy plasma dynamic synthesis of metal oxides in a carbon dioxide medium using the Ti – O and Fe – O systems as an example. By applying a sectioned capacitive energy storage device and a coaxial magnetoplasma accelerator with titanium and steel electrodes, which are the main elements of the plasma dynamic synthesis system, nano- and micropowders of iron and titanium oxides were obtained by utilizing CO2. Synthesis of powders was carried out as a result of plasma-chemical reactions occurring during high-speed sputtering of carbon electric discharge plasma into the atmosphere of a reactor chamber filled with carbon dioxide. The possibility of controlling the volume of CO2 utilized in the synthesis process by changing the type of electrodes and the number of successive power supply pulses is shown. It has been established that when using titanium electrodes and a multi-pulse operating mode in the considered system, it is possible to utilize up to 15 vol. % of CO2 to obtain up to ~ 9 g of dispersed products. It should be noted that when titanium electric discharge plasma is sputtered in a CO2 medium, the formation of “classical” rutile and anatase phases, as well as Magneli phases and titanium carbide without traces of pure metal is observed. This indicates that when implementing the plasma dynamic synthesis, it is possible not only to utilize carbon dioxide, but also to obtain useful powder products, which can later be used as feedstock for various applications.
Measurement of diffusion coefficients of interstitial impurities in Zr – 1 wt. % Nb alloy by internal friction method
Authors:   National Research Nuclear University MEPhI, Anan’in V. M. , Kalin B. A. ,   National Research Nuclear University MEPhI
Published: July 2022

In alloys with a GPU lattice, it is possible to observe a relaxation of the Snukovsky type if there is a certain amount of substitution impurities in it. However, it is impossible to calculate the diffusion coefficients of the introduction impurities by the measured relaxation time by analogy with BCC alloys, just because of the possible interaction with substitution atoms. However, in some cases, if reliable diffusion data are available for an alloy close in composition to the studied one, the relaxation time can be calculated from the ratio τr = τr0·exp(Hm/RTm), where Hm, Tm are the parameters of the relaxation maximum of the impurity from the experiment, and τr0 can be calculated from the formula D0 = c02/(16·τr0) for the GPU lattice, taking D0 from the corresponding diffusion expert data. In this way, the diffusion coefficients of the introduction impurities in the alloy Zr – 1 wt. % Nb are calculated for several states of samples.
Features of niobium damage by pulse laser radiation in comparison with beam-plasma impact
Authors:   Baikov Institute of Metallurgy and Material Science RAS, Pimenov V. N. , Borovitskaya I. V. ,   Baikov Institute of Metallurgy and Material Science RAS, Demin A. S. ,   Baikov Institute of Metallurgy and Material Science RAS, Epifanov N. A. ,   Baikov Institute of Metallurgy and Material Science RAS, Kazilin E. E. ,   Baikov Institute of Metallurgy and Material Science RAS, Latyshev S. V. ,   Baikov Institute of Metallurgy and Material Science RAS, Maslyaev S.A. ,   Baikov Institute of Metallurgy and Material Science RAS, Morozov E. V. ,   Baikov Institute of Metallurgy and Material Science RAS, Sasinovskaya I. P. ,   Baikov Institute of Metallurgy and Material Science RAS, Bondarenko G. G. ,   National Research University Higher School of Economics, Gajdar A. I. ,   Research Institute of Advanced Materials and Technologies
Published: July 2022

The features of damageability of niobium by pulsed fluxes of laser radiation (LR) in the free-running modes (power density qFR = 105 – 106 W/cm2 with pulse duration τFR = 700 μs) and Q-switch mode (q = 108 – 109 W/cm2, τMD = 80 ns) in comparison with the pulsed effects of helium ion (HI) and helium plasma (HP) fluxes in the Plasma Focus (PF) setup at a flux power density qi ~ 108 W/cm2 and qp ~ 107 W/cm2, respectively and pulse durations τi ≈ 30 – 50 ns and τp ≈ 100 ns. LR fluxes were exposed to Nb in air; the working gas in the PF chamber was helium. It is shown that, in contrast to the effect of IG and HP fluxes on niobium in the PF installation, which contribute to the erosion of the material, the irradiation of niobium by pulsed LR in air fluxes under the conditions implemented does not cause noticeable surface erosion. When Nb is exposed to pulsed LR in the FR mode, the melt interacts with the air and forms on the irradiated surface of a thin film of elements of the liquid and gas phases. A similar nature of damage to Nb under the conditions of laser and beam-plasma treatment was found: a wavy relief of the irradiated surface with the presence of drop-like fragments on it, extended wave crests and microcracks. Irradiation of Nb by pulsed LR fluxes in the FR mode leads to the formation in the surface layer (SL) of sections with block and cellular structures, which are also formed after experiments in the PF chamber. It was found that after laser treatment in the FR and Q-switch modes, bubbles (blisters) are not formed in the SL of niobium, which are always present on the irradiated surface when exposed to pulsed fluxes of HI and HP in the PF chamber due to the implantation of helium ions in Nb. It is noted that in laser experiments there is no possibility of implanting working gas ions into the material, which is characteristic of beam-plasma impacts in PF devices, which affects the parameters of damageability and modification of the structure of the irradiated SL.
Chemical properties and electronic structure of molybdenum oxysulfide films for promising photoelectrocatalysts for hydrogen production
Authors:   National Research Nuclear University “MEPhI”, Nevolin V. N. , Romanov R. I. ,   National Research Nuclear University “MEPhI”, Fominski D. V. ,   National Research Nuclear University “MEPhI”, Rubinkovskaya O. V. ,   National Research Nuclear University “MEPhI”, Fominski V. Yu. ,   National Research Nuclear University “MEPhI”
Published: July 2022

The effect of sulfur and oxygen concentrations on the formation of chemical bonds in films based on the ternary compound Mo – S – O, which is of interest for solving the problem of obtaining effective thin-film catalysts for electrochemical, especially photo-activated, water splitting reaction, has been studied. The films were created by pulsed laser deposition in a mixture of gases (argon and oxygen) at room temperature of the substrate. Factors that have an important effect on the position of the Fermi level in the band gap of a ternary compound are revealed, which largely determines the choice of components in hybrid and heterostructures for photoelectrodes. The change in the chemical state of Mo – S – O films in the electrochemical process of hydrogen evolution in an acid solution has been studied. Character of changes in the local packing of atoms (self-organization) are revealed, manifested in a decrease in the concentration of metal oxide clusters and an increase in the concentration of Mo – S clusters on the surface of such films. The thermodynamic analysis which was carried out using the density functional theory showed that when oxygen is removed from the surface of Mo – S – O films and, as a result, the hybrid structure MoSx/(Mo – S – O) is formed, the efficiency of hydrogen evolution can be controlled by the quantum chemical interaction of different clusters. In this case, only certain combinations of clusters can provide a sufficiently high catalytic activity.
Simultaneous synthesis of porous ceramic materials with obtaining catalytic converters of [Re,W]/α-Al2O3 composition for hydrocarbon dehydrogenation
Authors:   Merzhanov Institute of Structural Macrokinetics and Materials Science Russian Academy of Sciences, Uvarov V. I.
Published: July 2022

A porous ceramic catalytic converter based on a coarse powder filler α-Al2O3 with an ultrafine strengthening binder of MgO + SiC + SiO2 composition and catalytically active components of Re2O7 and WО3 (up to 4 mass %) was synthesized. Double-sided compaction of the initial mixture at P = 70 to 90 MPa and sintering of the samples at 1200°C to 1400 °C was used. Ceramic catalytic converters with an open porosity of about 40% and a pore size of 0.5 to 1.5 µm were synthesized. Styrene selectivity of about 30% and productivity up to 30 g/(h⋅dm3) in the temperature range from 600 to 700 °С have been experimentally achieved. The degree of catalyst carbonization during the experiment (6 h) did not exceed 0.31 wt. %. A high selectivity for styrene of about 30 % was achieved during the experiments; it was realized in temperature range from 600 to 700 °C. As a result of the research, the scientific basis of a new one-stage technology for obtaining a porous ceramic was developed with simultaneous imparting of catalytic properties. The obtained ceramic catalytic converters can produce styrene with high efficiency and resistance to coke formation in a wide temperature range.
Microporous carbon material with high adsorption rates
Authors:   Tambov State Technical University, Memetova A. E. , Zelenin A. D. ,   Tambov State Technical University, Memetov N. R. ,   Tambov State Technical University, Babkin A. V. ,   Tambov State Technical University,   JSC State Research and Design Institute of Rare Metal Industry “Giredmet”, Gerasimova A. V. ,   Tambov State Technical University
Published: July 2022

A compacted microporous carbon material (CMC-032) was obtained, which has a number of unique properties: a high specific surface area according to BET (SBET = 2384 m2/g), a large volume of micropores (~ 0.95 cm3/g), and a very high ability to retain methane 336 m3/v3. Sorbent CMC-032 is obtained by activating polymer raw materials with potassium hydroxide and compaction by hot pressing using polyvinyl alcohol as a binder. In the most demanded range of methane accumulation pressures of 3,5 – 10,0  MPa, the amount of accumulated methane in the system with CMC-032 reaches 270 m3/m3. The amount of methane stored in the system with and without CMC-032 adsorbent at 100 bar differs by about 3 times. The physicochemical properties of the obtained CMC-032 adsorbent were studied using methods including adsorption-desorption of N2 at 77 K, X-ray diffraction analysis, FTIR spectroscopy, Raman spectroscopy, and transmission electron microscopy. Based on the adsorption characteristics, it was found that CMC-032 is a promising material for storing natural gas methane. It is assumed that the high adsorption capacity is due to the high micropore volume and packing density.
Using composite materials with magnesium matrix for plain bearings
Authors:   Togliatti State University, Kovtunov A. I. , Khokhlov Yu. Yu. ,   Togliatti State University, Myamin S. V. ,   Togliatti State University
Published: July 2022

Technology for the formation of composite materials with a magnesium matrix and a filler based on lead alloys has been proposed, which makes it possible to increase the tribotechnical properties of plain bearings. According to the proposed technology, a porous magnesium matrix with open porosity is obtained by filtration of a magnesium melt through water-soluble granules, which, after solidification of the melt, are leached into a solution of acetic acid. To obtain a composite casting, a porous magnesium matrix is impregnated with lead or lead alloys. The conducted studies of the formation processes of a composite material with a magnesium matrix and babbit filler showed that the proposed technology makes it possible to obtain composite materials with satisfactory filling of porous magnesium with babbit without discontinuities and visible defects. Filling temperature was 500 – 550 °С and preliminary heating temperature of porous magnesium 200 – 350 °С. Properties of the obtained composite with a magnesium matrix and Babbitt filler showed that the material has a lower, almost 2 times, density, higher thermal conductivity and better performance properties than lead-based alloys.
Theoretical Foundations of the Grammatical System of English for Radiotelephony Communication in Aviation
Authors: Lysenko Sergey Vladimirovich
Published: July 2022

The research aims to consider the particularities of the grammatical system of professional English for radiotelephony communication in aviation. The paper is novel in that it is the first to analyse the theoretical basis of the language grammatical system, which should ensure the unambiguity of speech perception and the possibility of rapid transmission of oral messages by means of radio communication in both standard and difficult speech situations. The research findings prove that the effective functioning of English for radiotelephony communication in aviation is achieved using a limited set of grammatical means and short syntactic constructions, which ensures an optimal ratio of the reliability and brevity requirements for this professional language.
The Ability of Russian Particles to Communicate the Semantics of the Extreme: An Analytical Review
Authors: Klyushina Alena Mikhailovna
Published: July 2022

The paper is an analytical review of Russian studies describing the semantics and features of the functioning of Russian particles. The research aims to get a detailed insight into the history of description of Russian particles and the peculiarities of their communication of various meanings, namely the semantics of the extreme. Scientific novelty lies in the fact that the study, review and analysis of Russian works investigating the peculiarities of Russian particles usage complement the author’s cycle of academic papers on the issues of the functional-semantic category of the extreme in the Russian language. As a result, the author comes to the conclusion that particles are undoubtedly constituents of the field of the semantics of the extreme.
DREAM Concept in the Novel “Ladoga” by O. Grigorieva
Authors: Usacheva Olga Alexandrovna , Chernyavskaya Nadezhda Anatolievna , Makunina Daria Sergeevna
Published: July 2022

The aim of the study is to identify the features of the Slavic folklore motives interpretation in the conceptualization of reality in the individual author’s worldview. The scientific novelty of the work lies in the fact that for the first time it studies the content structure of the DREAM concept in O. Grigorieva’s novel “Ladoga”. As a result of the study, the representatives of the DREAM concept in the novel are identified; its cognitive signs are revealed; the methods of figurative modelling of the concept and its value component are characterized. It has been found that in the author’s model of the world, the state of dream is presented as special reality. The DREAM concept has an ambivalent character and plays a key role in the compositional plot construction of the novel.
Neologism Emotivity in the Coronavirus Period
Authors: Semerdzhidi Valentina Nikolaevna , Resepova Victoria Konstantinovna
Published: July 2022

The aim of the research is to reveal the expressive category of figurativeness in the emotive semantics of neologisms which express people’s negative emotions relating to the coronavirus pandemic. The scientific novelty lies in examining the emotive semantics of coroneologisms through conceptual images that convey fear, anxiety and despair. The results of the study show that there are four groups of images in the basis of coroneologisms formation: images of natural phenomena, images of militaristic activity, images of animals and allusive images as a hint at historic and political facts with a catastrophic effect.
Creative Neologisms as a Result of Hybrid Word Formation in the German and Russian Colloquial Speech
Authors: Zavalishina Liia Viktorovna , Nefedova Lyubov Arkadyevna
Published: July 2022

The aim of the study is to identify creative neologisms of the German and Russian colloquial speech formed through hybrid word formation, which is a combination of autochthonous and borrowed elements. The article discusses the main ways of forming neologisms using hybrid components. The scientific novelty of the research lies in studying the linguo-creative interaction of autochthonous and borrowed vocabulary in the process of colloquial neologisms formation. As a result of the study, it has been found that the main mechanisms of linguo-creative activity through hybrid word formation are universal. However, it results in language-specific colloquial units.
William Morris’s “The Wood beyond the World”: Possibilities of Reading and Translating from English into Russian
Authors: Aristov Aleksei Yur’evich
Published: July 2022

The aim of the study is to conduct a translational analysis of two currently existing Russian translations of William Morris’s novel “The Wood beyond the World”, the first fantasy novel. The analysis is carried out at the graphic-phonetic, lexical, syntactic levels, the possibility of different readings of the novel leading to different translations is illustrated. The scientific novelty of the study lies in a comprehensive comparative analysis carried out on previously unstudied material. A comprehensive comparative analysis of the techniques used by various translators to solve problems, most of which are related to the transfer of the poetic style (poetic diction) of the novel, is carried out. As a result of the work, a detailed classification of the author’s stylistic devices has been given requiring a separate translation decision; various methods used by the translators of one of the late novels by William Morris have been described.
ATIVIDADE PRÁTICA DE UMA ENFERMEIRA NA UNIDADE DE DIAGNÓSTICO POR IMAGEM: RELATO DE EXPERIÊNCIA
Authors: Sales Gomes de Sousa Samara , Gomes Nogueira Ferreira Adriana , Letícia Tavares Palmeira Rolim Isaura , Maia Pascoal Lívia , Cristina Oliveira Silva Andréa
Published: July 2022

OBJETIVO: Descrever as atividades desenvolvidas por uma enfermeira em Unidade de Diagnóstico por Imagem de um Hospital Universitário. MÉTODO: Trata-se de um estudo descritivo do tipo relato de experiência que descreve a atuação da enfermeira a partir da sua atividade profissional no período de novembro de 2014 a março de 2019. RESULTADOS: A atuação do enfermeiro está voltada para o cuidado do usuário submetido a procedimentos diagnósticos e terapêuticos em que se faz necessário conhecimentos e habilidades de gerência de enfermagem; planejamento e implementação da assistência de enfermagem; educação em saúde e segurança do paciente. CONSIDERAÇÕES FINAIS: A atuação do enfermeiro nesta unidade visa evitar riscos e garantir a segurança do paciente a partir do desenvolvimento de ações planejadas, educativas, gerenciais, de ensino e pesquisa.
Zero and One Inflated Item Response Theory Models for Bounded Continuous Data
Authors: Molenaar Dylan , Cúri Mariana , Bazán Jorge L.
Published: July 2022

Bounded continuous data are encountered in many applications of item response theory, including the measurement of mood, personality, and response times and in the analyses of summed item scores. Although different item response theory models exist to analyze such bounded continuous data, most models assume the data to be in an open interval and cannot accommodate data in a closed interval. As a result, ad hoc transformations are needed to prevent scores on the bounds of the observed variables. To motivate the present study, we demonstrate in real and simulated data that this practice of fitting open interval models to closed interval data can majorly affect parameter estimates even in cases with only 5% of the responses on one of the bounds of the observed variables. To address this problem, we propose a zero and one inflated item response theory modeling framework for bounded continuous responses in the closed interval. We illustrate how four existing models for bounded responses from the literature can be accommodated in the framework. The resulting zero and one inflated item response theory models are studied in a simulation study and a real data application to investigate parameter recovery, model fit, and the consequences of fitting the incorrect distribution to the data. We find that neglecting the bounded nature of the data biases parameters and that misspecification of the exact distribution may affect the results depending on the data generating model.
Gynaecologic and Systemic Comorbidities in Patients with Endometriosis: Impact on Quality of Life and Global Health
Authors: Capezzuoli Tommaso , Orlandi Gretha , Clemenza Sara , Ponziani Ilaria , Sorbi Flavia , Vannuccini Silvia , Petraglia Felice
Published: July 2022

Objectives: Endometriosis is an inflammatory disease characterized by a frequent association with gynecologic and systemic comorbidities. Our aim was to evaluate which gynecologic and systemic comorbidities occur in women affected by endometriosis and their impact on quality of life and global health. Mechanism: A literature search of the PubMed, Cochrane Library, Scopus and Web of Science databases was performed to identify the relevant studies published before December 31, 2021. We selected clinical studies, systematic reviews, and meta-analyses in English. Findings in Brief: Endometriosis is strongly associated with gynecologic (adenomyosis, uterine fibroids, polycystic ovarian syndrome-PCOS) and systemic (autoimmune, inflammatory, psychiatric and neurological disorders) comorbidities that impair women quality of life and global health through multiple mechanisms, influencing everyday life and work activities. Conclusions: Endometriosis is a chronic disease, impairing multiple functioning areas and affecting women’s health and everyday life. Considering the co-existence of multiple both gynecological and non-gynecological disorders, endometrisois needs a multidisciplinary approach. Thus, specialized referral centres are warranted for a personalized management, focused on patient symptoms and comorbidities.
Association of Tumor Markers with Total Testosterone in the Serum of Women with Polycystic Ovary Syndrome
Authors: Zhang Jinghua , Pan Manman , Zhang Qing , Wang Fangfang , Qu Fan
Published: July 2022

Background: To investigate the correlations between serum levels of tumor markers [including carbohydrate antigen 125 (CA125), carcino-embryonic antigen (CEA) and alpha fetoprotein (AFP)] and the total testosterone of the patients with polycystic ovary syndrome (PCOS). Methods: The data was collected from 890 healthy Chinese women and 480 women with PCOS, including serum total testosterone (TTE), follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), progesterone (PGN), prolactin (PRL), CA125, AFP and CEA. The serum levels of reproductive hormone and tumor markers in the women with PCOS were compared among the subgroups in accordance with the classification of TTE quartiles. To further explore the association between CA125, AFP, CEA and the TTE levels, Spearman correlation analysis was performed. Results: PCOS had significantly lower CA125, and higher AFP and CEA levels in the serum than the healthy controls (p = 0.000, p = 0.015 and p = 0.001, respectively). Four subgroups divided by TTE showed significant differences in CA125 levels (p = 0.017). The Spearman correlation analysis also showed that CA125 was significantly negatively associated with serum TTE levels (p = 0.022). Conclusions: The serum level of CA125 is significantly lower and significantly correlated to the hormonal status of PCOS. AFP and CEA are significantly higher in PCOS.
Altered Expression of STAT3, RORγt, and IL-17A Proteins and Th17 Cell in Intrahepatic Cholestasis of Pregnancy
Authors: Wu Yu-Xia , Chen Qian , Chen Qiu-He , Shan Dan , Hu Ya-Yi
Published: July 2022

Background: Intrahepatic cholestasis of pregnancy (ICP) is a disorder specifically associated with pregnancy. Recent evidence suggests that the T helper 17 (Th17) cell population is related to a maternal and foetal immune imbalance associated with ICP. However, there has been insufficient attention paid to the potential roles of signal transducer and activator of transcription 3 (STAT3) and RAR-related orphan receptor gamma (RORγt) in modulations of Th17 cell in ICP. Accordingly, the purpose of our study was to investigate the alterations of Th17 cell in placenta and peripheral blood of patients with ICP and correlations between Th17 cell and STAT3, RORγt, interleukin (IL)-17A in ICP. Methods: Nine pregnant women with ICP and nine women with normal pregnancy served as the ICP and control groups, respectively. STAT3, RORγt, and IL-17A expression were examined by immunohistochemistry and western blotting in placental tissue. Flow cytometry was used to quantify Th17 cell in blood of peripheral circulation. We compared data between groups using Chi-square tests or paired t tests. Pearson or Spearman coefficients were used to measure correlations. Results: STAT3, RORγt, and IL-17A were mainly expressed in the trophoblasts of the two groups of patients. Comparatively to the control group, placental levels of STAT3, RORγt, and IL-17A proteins were significantly elevated in ICP group, as was maternal levels of Th17 cell in peripheral blood. Moreover, placental IL-17A protein level showed significantly positive relationships with placental STAT3 (r = 0.97, p = 2e-05) and RORγt (r = 0.91, p = 0.01) protein in control group, however, not in ICP group (STAT3, r = 0.5, p = 0.17; RORγt, r = 0.62, p = 0.07). Conclusions: Women with ICP showed an increase in Th17 cells in comparison to women with normal pregnancies. STAT3 and RORγt may increase Th17 cell proliferation and differentiation, appears to be altered in ICP. ICP may be adversely affected by excessive accumulation of Th17 cell.
STRATEGI KEBIJAKAN PENANGANAN STUNTING PROPINSI JAWA BARAT DI MASA PANDEMI COVID 19 (ANALISIS IMPLEMENTASI DAN SOLUSI) STRATEGY OF STUNTING HANDLING POLICY IN WEST JAVA PROVINCE DURING THE COVID-19 PANDEMI (ANALYSIS OF IMPLEMENTATION AND SOLUTION)
Authors: Fitrianingrum Lia
Published: July 2022

ABSTRACT               Stunting in Indonesia has an equitably high prevalence. Indonesia is projected to experience peak productive population growth with a demographic bonus in 2035. However, this demographic bonus will not be useful or will even become a state burden if current under five high prevalence of stunting is not corrected. Stunting causes economic losses of 2-3% of Gross Domestic Product (GDP). Based on world bank data, Indonesia's GDP was 13,000 trillion in 2017, so the loss due to stunting was estimated at 260-390 trillion. Role of each region in contributing to stunting rates is also diverse, one of which is West Java Province, one of the provinces with the largest population in Indonesia. Efforts to reduce stunting rate in West Java have become even more difficult during the COVID-19 pandemic, where 83.9% of immunization services are estimated to be disrupted, and it is also estimated that the stunting rate will increase after this pandemic. Therefore, it is necessary to analyse the implementation strategy of stunting handling policy in West Java Province. The purpose of this study was to explore the real conditions of the policy implementation, so that it could be input to relevant stakeholders. This study used a qualitative approach. Data collection techniques were carried out by collecting secondary data, observation, and interviews. The results of the study showed that the content, process, context, and actors as the elements in the implementation of stunting handling policies in West Java worked in synergy with each other. Besides the four elements, leadership was another very important element. Leadership in West Java really determined the optimal role of content, process, context, and actors’ elements.Keywords: strategy, policy implementation, stunting, West Java Province
KREATIVITAS DAN INOVASI UNTUK MENOPANG KEBERLANJUTAN PENGEMBANGAN KOMPETENSI SUMBER DAYA MANUSIA DI KEMENTERIAN PEKERJAAN UMUM DAN PERUMAHAN RAKYAT SAAT PANDEMI COVID-19
Authors: Hayati Neuneung Ratna
Published: July 2022

Pandemi Covid-19 yang saat ini terjadi, telah dan akan memengaruhi berbagai aspek kehidupan termasuk keberlangsungan proses bisnis yang ada di organisasi Kementerian Pekerjaan Umum dan Perumahan Rakyat (PUPR). Artikel ini bertujuan untuk berbagi pengetahuan mengenai best practices yang telah dan sedang dilakukan oleh Pusat Pendidikan dan Pelatihan Jalan, Perumahan, Permukiman, dan Pengembangan Infrastruktur Wilayah (Pusdiklat JPPPIW) dalam mendorong munculnya berbagai kreativitas dan inovasi untuk mengembangkan pola strategi mengembangkan kompetensi sumber daya manusia yang dimiliki. Tulisan ini menggunakan pendekatan metode kualitatif yang berfokus pada fakta implementasi inovasi pengembangan SDM yang dilakukan. Hasil pembahasan menunjukkan desain pelatihan yang dikembangkan oleh Pusdiklat JPPPIW menggunakan model ADDIE (Analyze, Design, Development, Implementation, dan Evaluation) yang telah dimodifikasi dengan memanfaatkan teknologi untuk menjawab kebutuhan pengembangan kompetensi dalam situasi Pandemi Covid-19. Berbagai kreativitas yang diwujudkan dalam bentuk inovasi diharapkan mampu menjadi penyangga keberlanjutan pengembangan kompetensi SDM PUPR terutama saat pandemi Covid-19 terjadi. Artinya, berbagai pola pengembangan SDM jika dilakukan dengan benar dan sistematis akan tetap dapat mendorong pencapaian tujuan organisasi dan beradaptasi lebih cepat terhadap tuntutan perubahan lingkungan.
Analisis Morfometrik Ikan Nila (Oreochromis nilototicus) Hasil Budidaya Tambak dan Hasil Pancingan Masyarakat di Sungai Jeneberang, Kelurahan Pangkabinanga, Kabupaten Gowa
Authors: Marsuki Nur Ainun
Published: July 2022

Hasil yang didapatkan berupa nilai akhir dari perhitungan data dengan menjumlahkan keseluruhan sampel ikan dari kedua tempat kemudian diambil nilai rata-ratanya.
Pendekantan Teori dan Praktek Konstitusi Undang Undang Dasar 1945
Authors: nadir Akhmad
Published: July 2022

menganut sistem pemerintahan Presidensil, dimana adanya pemisahan kekuasaan yaitu Eksekutif, Legislatif dan Yudikatif yang berdasarkan prinsip “checks and balances”, ketentuan ini tertuang dalam konstitusi, namun tetap diperlukan langkah penyempurnaan, terutama pengaturan atas pembatasan kekuasaan dan wewenang yang jelas antara ketiga lembaga Negara tersebut. Penulisan ini menggunakan metode dalam penelitian hukum yuridis-normatif, penulis mengumpulkan data sekunder yang berkaitan dengan permasalahan yang dibahas kemudian dianalisis. Dalam penulisan ini, penulis ingin mengetahui dan membahas berbagai teori dan praktek berdasarkan UUDNRI TAHUN 1945 atas pelaksanaan sistem pemerintahan Indonesia. Secara teoritis kewenangan lembaga-lembaga negara di Indonesia mengarah pada sistem pemerintahan presidensil, namun kemudian secara praktek dalam menjalankan fungsi dan kewenangan, lembaga negara tidak mencerminkan bahwa sistem pemerintahan Indonesia menganut pemisahan kekuasaan yang ada dalam sistem pemerintahan presidensil akan tetapi lebih dekat pada sistem pembagian kekuasaan. Sehingga ketentuan yang diterapkan berdasarkan UUDNRI TAHUN 1945 diperlukan kembali upaya penyempurnaan, agar secara konsepsional dan prakteknya dapat berjalan secara ideal.
KEANEKARAGAMAN JENIS IKAN KELAS CHONDRYTHYES HASIL TANGKAPAN NELAYAN DI POETERE MAKASSAR
Authors: Hamka Fitha Kaamiliyaa
Published: July 2022

Ichthyology dianggap sebagai elemen terpenting dari perikanan yang hilang, karena berfokus pada studi tentang ikan sebagai objek utama. Sulawesi Selatan salah satu wilayah yang memiliki beragam potensi sumberdaya alam di antaranya di bidang perikanan tangkap. Salah satu wilayah yang menjadi sasaran dalam aktivitas penangkapan hasil tangkapan ikan adalah Pelabuhan paotere yang merupakan salah satu dari tiga pelabuhan laut yang dimiliki oleh pelabuhan Makassar. Metode penelitian dilakukan dengan metode survei dan teknik observasi. Hasil kunjungan dan wawancara langsung beberapa nelayan poetere, alat tangkap yang digunakan nelayan yaitu menggunakan alat pancing dan jaring. Ikan hasil tangkap menggunakna alat tangkap pancing yaitu Neotrygon kuhli, Himantura uarnak, Himantura dalyensis, Carcharhinus amblyrhynchoides, Mustelus griseus. Kemudian Ikan hasil tangkap menggunakna alat tangkap jaring yaitu Neotrygon kuhli, Taeniura lymma, Himantura uarnak, Carcharhinus isodon. Kebanyakan jenis ikan pari yang didaptkan oleh nelayang menggunakan alat pancing dan jaring yaitu Neotrygon kuhlii dan Himantura dalyensis
Teladentistry and distance learning :Access to oral health state : systematic Reviews
Authors: kotb shaymaa Hussein Rafat
Published: July 2022

:Covid19 pandemic has changed the vision on how to deal in emergency situations .Advanced technology and spreading growth of internet connection encourage people to use it to obtain helpful advice in critical climate of covid 19 crisis . The aim of this study to through the light on importance of teledentistry in critical emergency situations .
Tự sát – Wikipedia tiếng Việt
Authors: Nguyen Van-Quang
Published: July 2022

Tự sát (Hán tự: 自殺, có nghĩa là "tự giết hoặc là tự tử, tự vẫn", tiếng Anh: suicide. Bắt nguồn từ Tiếng Latinh: Suicidium, từ chữ sui caedere nghĩa là "giết chính mình") hay tự tử là hành động của một người cố ý gây ra cái cái chết cho chính mình. ***** Chỉ dành cho mục đích lưu trữ thông tin *****
MINI PROYEK IKHTIOLOGI
Authors: andriani sri
Published: July 2022

Ikan merupakan sumber protein hewani yang memiliki beberapa keunggulan dibandingkan sumber protein hewani lain, salah satu sumber protein hewani itu adalah ikan lele. Penelitian ini bertujuan untuk mengetahui pengaruh pertumbuhan berat ikan lele (Clarias Batracus) terhadap pemberian pakan berbeda. Penelitian ini dilaksanakan pada 27 Juni 2022 sampai 11 Juli 2022. Parameter yang diamati dalam penelitian ini adalah berat ikan lele. Penelitian dilakukan dengan menggunakan metode eksperiment dengan menggunakan 2 perlakuan yaitu pemberian pakan dengan membandingkan antara pemberian pakan ikan buatan pabrik berupa pellet dan pakan usus ayam. Pemberian pakan sebanyak 3 kali sehari selama 16 hari pemeliharaan.
An adaptive auto-reduction solver for speeding up integration of chemical kinetics in atmospheric chemistry models: implementation and evaluation in the Kinetic Pre-Processor (KPP) version 3.0.0
Authors: Lin Haipeng , Long Michael , Sander Rolf , Yantosca Robert , Estrada Lucas , Shen Lu , Jacob Daniel
Published: July 2022

Kinetic integration of large and stiff chemical mechanisms is a computational bottleneck in models of atmospheric chemistry. It requires implicit solution of the coupled system of kinetic differential equations with time-consuming construction and inversion of the Jacobian matrix. We present here a new version of the Kinetic Pre-Processor (KPP 3.0.0) for fast integration of chemical kinetics featuring a range of improvements over previous versions in performance, diagnostics, versatility, and community openness. KPP 3.0.0 includes a new adaptive auto-reduction solver to decrease the size of any mechanism locally and on the fly under conditions where full complexity is not needed, by partitioning species as “fast” or “slow” based on their local production and loss rates. Previous implementations of this adaptive solver suffered from excessive overhead in the repeated construction of the local Jacobian matrix or were hard-wired to specific mechanisms. Here we retain the general applicability of the method to any mechanism and avoid overhead by using pre-computed Jacobian matrix terms for the full mechanism and cropping the matrix locally to remove the slow species with no change in memory allocation. We apply this adaptive solver within KPP 3.0.0 to the GEOS-Chem global 3-D model of atmospheric chemistry and demonstrate a 32% reduction in solver time while maintaining a mean error lower than 1% for key species in the troposphere.
Large hot provinces at the base of the mantle stabilise the palaeomagnetic field
Authors: Biggin Andrew , Davies Chris , Mound Jonathan , Bono Richard
Published: July 2022

A crucial characteristic of Earth’s magnetic field, known since 1600, is that it approximates a dipole (bar magnet) aligned with the planetary rotation axis. Previous studies have disagreed over the extent to which this situation has persisted through geological time which is important for determining solar wind shielding and building palaeogeographic reconstructions. It has recently become possible to quantify this axial dipole dominance back in time using the equatorial variability of the palaeomagnetic field recorded in rocks. Here we show that this aspect of palaeomagnetic field behaviour was extraordinarily stable across three periods spanning the last 3 billion years despite being an unstable characteristic in most numerical geodynamo simulations. We further demonstrate a means to reproduce this stability in new rapidly rotating and turbulent geodynamo simulations. Large, seismically-inferred, hot provinces in the lowermost mantle suppress core flow beneath them, impose large-scale order on the magnetic field emerging from the core at low latitudes, and stabilise the palaeomagnetic behaviour of the simulations enabling them to reproduce the observations. Our combined modelling and observational results suggest that features akin to these large low velocity provinces in the lowermost mantle today may have stabilised Earth’s magnetic field throughout much of geological time.
A network approach to climate change anxiety and its key related features
Authors: Heeren Alexandre , Mouguiama-Daouda Camille , McNally Richard J.
Published: July 2022

Research has pointed to startling worldwide rates of people reporting considerable anxiety vis-à-vis climate change. Yet, uncertainties remain regarding how climate anxiety’s cognitive-emotional features and daily life functional impairments interact with one another and with climate change experience, pro-environmental behaviors, and general worry. In this study, we apply network analyses to examine the associations among these variables in an international community sample (n = 874). We computed two network models, a graphical Gaussian model to explore network structure, potential communities, and influential nodes, and a directed acyclic graph to examine the probabilistic dependencies among the variables. Both network models pointed to the cognitive-emotional features of climate anxiety as a potential hub bridging general worry, the experience of climate change, pro-environmental behaviors, and the functional impairments associated with climate anxiety. Our findings offer data‐driven clues for the field’s larger quest to establish the foundations of climate anxiety.
Repeated Naming Affects the Accessibility of Non-Selected Words: Evidence from Picture-Word Interference Experiments
Authors: Wöhner Stefan , Mädebach Andreas , Schriefers Herbert , Jescheniak Jörg D.
Published: July 2022

This study traced different types of distractor effects in the picture-word interference (PWI) task across repeated naming. Starting point was a PWI study by Kurtz et al. (2018). It reported that naming a picture (e.g., of a duck) was slowed down by a distractor word phonologically related to an alternative picture name from a different taxonomic level (“birch” related to “bird”) when compared to an unrelated control, indicating that the alternative name was (phonologically) co-activated. Importantly, the effect was stable across repeated naming. The authors argued that this stability challenges adaptive models of word production according to which co-activated but non-selected words become less accessible for future retrieval; such a change in lexical accessibility should have been reflected in reduced interference. Using a similar experimental protocol as Kurtz et al., our study looked at the stability of different distractor effects in PWI. Interference from a distractor word phonologically related to an alternative name was stable across repeated naming, replicating Kurtz et al. In contrast, interference from a distractor word denoting a semantic category coordinate (“stork”) was reduced across repeated naming. A similar pattern was found for a distractor word corresponding to an alternative name (“bird”). Facilitation from a distractor word phonologically related to the target name (“dust”), in contrast, was stable across repeated naming. We discuss implications of these findings with respect to the issue of changes in the accessibility of lexical representations, the use of the PWI task in this context, and the use of this task in general.