bluuebunny/crossref_metadata_2025 huggingface dataset:
Harmonising, improving and using social and recreational data in National Forest Inventories across Europe
Authors: Atkinson Mark A. , Edwards David M. , Jensen Frank Søndergaard , van der Jagt Alexander P. N. , Ditchburn Ben R. , Sievänen Tuija , Gasparini Patrizia
Published: July 2020

Key message

National Forest Inventories (NFIs) hold promise for monitoring and valuing of non-productive forest functions, including social and recreational services. European countries use a range of methods to collect social and recreational information within their NFI methodologies. Data collected frequently included general and recreation-specific infrastructure, but innovative approaches are also used to monitor recreational use and social abuse.

Context

Social and recreational indicators are increasingly valued in efforts to measure the non-productive value of forests in Europe. National Forest Inventories (NFIs) can be used to estimate recreational and social usage of forest land at a national level and relate this use to other biophysical, spatial and topographical features. Nonetheless, there is little information concerning the extent.

Aims

The study aims to identify the coverage of social and recreational data present in European NFIs including the types of data recorded as part of the NFI methodologies across European countries. It also aims to examine contrasting methods used to record social and recreational data and present recommendations for ways forward for countries to integrate these into NFI practice.

Methods

A pan-European questionnaire was designed and distributed to 35 counties as part of the EU-funded project Distributed, Integrated and Harmonised Forest Information for Bioeconomy Outlooks (DIABOLO). The questionnaire probed countries on all social and recreational data that was included within NFIs. Qualitative response data was analysed and recoded to measure the extent of social and recreational data recoded in European NFIs both as a function of the number of variable categories per country and the number of countries recording particular variables.

Results

Thirty-one countries reported at least one social or recreational variable over 12 categories of data. The most frequently recorded variables included ownership, general transport infrastructure and recreation-specific infrastructure. Countries collecting data over many different categories included Switzerland, Great Britain, Czech Republic, Luxemburg and Denmark.

Conclusion

The study proposes a specific set of indicators, based upon countries with well-developed social and recreational data in their NFIs, which could be used by other countries, and report on the extent to which these are currently collected across Europe. It discusses results and makes a series of recommendations concerning priorities for the inclusion of social and recreational data in European NFIs.
A new approach to evaluate linear programming problem in pentagonal neutrosophic environment
Authors: Das Sapan Kumar , Chakraborty Avishek
Published: July 2020

In this paper, authors disclose a new concept of pentagonal neutrosophic (PN) approach to solve linear programming (LP) problem. To best of our insight, there is no approach for solving PNLP problem. For the first time, we take up the PNLP problem where the objectives, constraints are considered as pentagonal neutrosophic numbers (PNN). To deign our algorithm, we described the PN arithmetic operation laws and mathematical computation in PNN environment. This proposed method is based on ranking function and convert to its equivalent crisp LP (CrLP) problem. The obtained CrLP issue is presently being tackled by any LP method which is effectively accessible. To legitimize the proposed technique, some numerical tests are given to show the adequacy of the new model.
A Simple, Centrifugation-Free, Sperm-Sorting Device Eliminates the Risks of Centrifugation in the Swim-Up Method While Maintaining Functional Competence and DNA Integrity of Selected Spermatozoa
Authors: Meitei Huidrom Yaiphaba , Uppangala Shubhashree , Sharan Krishna , Chandraguthi Srinidhi Gururajarao , Radhakrishnan Arunkumar , Kalthur Guruprasad , Schlatt Stefan , Adiga Satish Kumar
Published: July 2020

This pilot study was conducted to explore the benefits of using a centrifugation-free device based on the migration–sedimentation (MS) technique over centrifugation-based techniques in selecting competent spermatozoa, as compared with using split human semen samples. Ejaculates from 35 men undergoing semen analysis were split into four parts where one part was retained as the neat (NE) and the other three parts were subjected to sperm selection by using migration–sedimentation (MS), density gradient (DG) separation, and swim-up (SU) techniques. Sperm functional characteristics along with mitochondrial integrity, tyrosine phosphorylation, acrosome reaction, and ultrastructure were measured. The ability of selection techniques in reducing spontaneous and radiation-induced sperm DNA lesions was assessed by the TUNEL assay. In results, MS-selected spermatozoa had higher viability (P < 0.001), longevity in terms of total motility at the end of 6 and 18 h post-extraction (P < 0.001), and mitochondrial integrity (P < 0.001) compared with those selected by DG. Furthermore, spontaneous DNA lesions were significantly reduced in MS and SU fractions compared with NE (P < 0.001). Similarly, radiation-induced sperm DNA lesions were significantly lower in MS and SU fractions (P < 0.001) compared with DG. Ultrastructural analysis using scanning electron microscopy suggested a moderate, non-significant increase in the number of spermatozoa with normal head and mid-piece in MS fraction compared with other methods. In conclusion, the MS-based device offers a centrifugation-free, efficient, and reliable sperm selection method, making it suitable for partially equipped intra-uterine insemination (IUI) laboratories or office IUI programmes. Further research should focus on the safety and clinical usefulness of the device in assisted conception programmes in general and IUI in specific.
Clinicopathological Significance of Common Genetic Alterations in Patients With Acute Promyelocytic Leukemia
Authors: Nath Sukanta , Bhattacharyya Jina , Chandra Prem , Saxena Renu , Sazawal Sudha , Saikia Kandarpa Kumar
Published: July 2020

Objective/Background:

Acute myeloid leukemia (AML) is one of the common forms of hematological malignancy and acute promyelocytic leukemia (APL) is a unique subtype of AML conferring favorable prognosis. We aimed to determine the prevalence and prognostic impact of Fms-like tyrosine kinase 3 (FLT3), nucleophosmin 1 (NPM1) mutation, epidermal growth factor receptor (EGFR), and flow marker’s expression in patients with APL.

Methods:

In the present study, 165 de novo APL patients were molecularly characterized for promyelocytic leukemia (PML) breakpoint and additional genetic alterations. Reverse transcriptase polymerase chain reaction (PCR) and realtime PCR assays were used to detect genetic alterations.

Results:

PML/RARa was detected in 29/165 (17.5%) samples with breakpoint cluster region 1 (bcr1) in 17/29 (58.5%) and bcr3 in 12/29 (41.5%) samples. The prevalence of FLT3-ITD, NPM1, and EGFR were detected in 5/29 (17.5%), 11/29 (38%), and 5/29 (17.5%) patients, respectively. Patients expressing bcr-3 hybrid transcript had lower overall survival compared with bcr1 (p = .254). White blood cell (WBC) count was significantly higher in bcr3 in comparison with bcr1 patients (p = .002). Patients with positive EGFR expression (p = .042) and higher WBC (p = .002) were significantly associated with poor survival (p < .05).

Conclusions:

We documented the higher prevalence of bcr1 and confirmed that the association of FLT3-ITD significantly reduced the chances of survival in APL. The mortality rate of bcr3 was comparatively higher than that of bcr1. Higher WBC count and EGFR expression were significantly associated with poor survival.
Prolonged Brackish Water Exposure: A Case Report
Authors: Hughey Scott B. , McCoy Kari L. , Mills Aaron E.
Published: July 2020

Exposure to and consumption of brackish water are associated with an elevated risk of infection, hypernatremia, and hypothermia. Minimal data exist to support the diagnosis and treatment of patients with long-term brackish water exposure. We present a case of a patient who spent 5 to 10 d semisubmerged in the Elizabeth River in coastal Virginia. A 55-y-old male presented via ambulance after 5 to 10 d of being “stuck in the mud.” He was hypernatremic, with a sodium of 176 mEq·L-1, hypothermic to 34.5°C (94.1°F), and hypotensive at 88/50 mm Hg, with a sodium concentration of 176 mEq·L-1 and an osmolality of 412 mosm·kg-1. He developed pneumonia, with respiratory cultures growing Vibrio parahemolyticus, Klebsiella oxytoca, and Shewanella algae. He had pustules, which grew Aeromonas hydrophilia and Aeromonas caviae. A nasogastric tube was placed. Using suction, 500 mL of coarse sand and gravel was removed from his stomach. Antibiotics and intravenous fluids were given. The patient fully recovered after 3 wk and was discharged to rehabilitation. Exposure to brackish water can present a unique set of infectious and metabolic complications. Initial care should include treatment of metabolic derangements, such as hypovolemia, hypernatremia, and hypothermia, and treatment of infections with antibiotics based on knowledge of the most likely causative organisms.
Presidential Instability in Latin America: Why Institutionalized Parties Matter
Authors: Martínez Christopher A.
Published: July 2020

Pedro P. Kuczynski (Peru 2018) and Evo Morales (Bolivia 2019) are the most recent cases in a long list of Latin American presidents who have been forced out of office. We seek to contribute to understanding why some presidents fail to fulfil their terms by analysing the role of an actor overlooked by the extant literature on presidential failures: political parties. We hypothesize a non-linear relation between party institutionalization and the risk of presidential failure. That is, when parties are weakly or highly institutionalized, the hazard of presidential failure is lower than when parties are moderately institutionalized. We test this and other hypotheses with a survival analysis of 157 Latin American administrations (1979–2018). We also qualitatively explore how the occurrence (or non-occurrence) of certain events affects the risk of failure in three countries with different levels of party institutionalization. We find that party institutionalization – as well as legislative support, anti-government demonstrations, presidential scandals and economic growth – significantly affects the risk of presidential failure.
Posttraumatic stress symptomatology and abnormal neural responding during emotion regulation under cognitive demands: mediating effects of personality
Authors: Sun Michael , Marquardt Craig A. , Disner Seth G. , Burton Philip C. , Davenport Nicholas D. , Lissek Shmuel , Sponheim Scott R.
Published: July 2020

Posttraumatic stress disorder (PTSD) is often complicated by the after-effects of mild traumatic brain injury (mTBI). The mixture of brain conditions results in abnormal affective and cognitive functioning, as well as maladaptive behavior. To better understand how brain activity explains cognitive and emotional processes in these conditions, we used an emotional N-back task and functional magnetic resonance imaging (fMRI) to study neural responses in US military veterans after deployments to Iraq and Afghanistan. Additionally, we sought to examine whether hierarchical dimensional models of maladaptive personality could account for the relationship between combat-related brain conditions and fMRI responses under cognitive and affective challenge. FMRI data, measures of PTSD symptomatology (PTSS), blast-induced mTBI (bmTBI) severity, and maladaptive personality (MMPI-2-RF) were gathered from 93 veterans. Brain regions central to emotion regulation were selected for analysis, and consisted of bilateral amygdala, bilateral dorsolateral prefrontal (dlPFC), and ventromedial prefrontal/subgenual anterior cingulate (vmPFC-sgACC). Cognitive load increased activity in dlPFC and reduced activity in emotional responding brain regions. However, individuals with greater PTSS showed blunted deactivations in bilateral amygdala and vmPFC-sgACC, and weaker responses in right dlPFC. Additionally, we found that elevated emotional/internalizing dysfunction (EID), specifically low positive emotionality (RC2), accounted for PTSS-related changes in bilateral amygdala under increased cognitive load. Findings suggest that PTSS might result in amygdala and vmPFC-sgACC activity resistant to moderation by cognitive demands, reflecting emotion dysregulation despite a need to marshal cognitive resources. Anhedonia may be an important target for interventions that improve the affective and cognitive functioning of individuals with PTSD.
THE VIEW FROM OLYMPUS: THE MUSES’ SONG IN THEHOMERIC HYMN TO APOLLO
Authors: Spelman Henry L.
Published: July 2020

Apollo travels from Pytho to Olympus, and the other gods greet his arrival (186–93):ἔνθεν δὲ πρὸϲ Ὄλυμπον ἀπὸ χθονὸϲ ὥϲ τε νόημαεἶϲι Διὸϲ πρὸϲ δῶμα θεῶν μεθ’ ὁμήγυριν ἄλλων⋅αὐτίκα δ’ ἀθανάτοιϲι μέλει κίθαριϲ καὶ ἀοιδή.Μοῦϲαι μέν θ’ ἅμα πᾶϲαι ἀμειβόμεναι ὀπὶ καλῇὑμνεῦϲίν ῥα θεῶν δῶρ’ ἄμβροτα ἠδ’ ἀνθρώπωντλημοϲύναϲ, ὅϲ’ ἔχοντεϲ ὑπ’ ἀθανάτοιϲι θεοῖϲιζώουϲ’ ἀφραδέεϲ καὶ ἀμήχανοι, οὐδὲ δύνανταιεὑρέμεναι θανάτοιό τ’ ἄκοϲ καὶ γήραοϲ ἄλκαρ.

From there he goes quick as a thought from the earth to Olympus, to the house of Zeus, in order to join the gathering of the other gods. Immediately the immortals concern themselves with lyre music and song. All the Muses together, responding with their beautiful voice, hymn the divine gifts of the gods and the endurance of men, all that they have from the immortal gods and yet live ignorant and helpless, unable to find a remedy for death and a defence against old age.
Systems for evaluation of welfare on dairy farms
Authors: Krueger Angela , Cruickshank Jenifer , Trevisi Erminio , Bionaz Massimo
Published: July 2020

Animal welfare is an essential component of dairy production and several systems exist to evaluate the welfare of dairy cows. Here, we review and compare three well-known systems that operate at farm level from around the world (FARM, Welfare Quality®, and The Code of Welfare) and discuss their advantages and limitations. Despite having some commonalities, the programs evaluate different elements. We also briefly review an emerging system (Integrated Diagnostic Welfare System) that might address some of the shortcomings of the existing systems, especially the possibility of automating the evaluation of animal well-being and identifying any cause of poor welfare. None of the aforementioned systems has been fully validated for their ability to assess animal welfare using independent measurements. The future holds increased attention around the well-being of dairy cows and increased use of sensing technologies. There is an urgent need for dairy welfare evaluation systems that are scientifically validated, holistic, and that can take advantage of the use of sensing technologies to continuously monitor animal welfare.
Management practices that influence the welfare of calves on small family farms
Authors: Relić Renata , Starič Jože , Ježek Jožica
Published: July 2020

In this Research Reflection we review management practices in small family farms with less than 100 cows. Small farms represent the majority of farms in the EU and the world, and they are of great importance for the economy of a country. On cattle farms, the welfare of calves is of primary importance for the profitability of the herd, and poor management is one of the main factors influencing calf health and survival. Data on the risk factors for calf welfare issues in small-scale farms are limited. For this purpose, the literature data from six world countries were presented and compared, including Serbia and Slovenia where a survey related to the issue was carried out within the COST Action FA1308, DairyCare. Some practices within the following areas in calf management were considered: calving management, care for new-born calves, use of painful procedures, colostrum management, cow–calf separation, calf feeding, weaning, calf housing, and general monitoring. In each of the countries, the health and welfare of calves are threatened by some omissions in rearing practices and the major are related to the new-born calf management, the feeding and watering management, and the application of hygienic measures. Many farmers are well aware of the importance of proper calf rearing; others would need more incentive to improve calf management. Each country should pay attention to the education of farmers about the most common deficiencies in calf management.
Play and social behaviour of calves with or without access to their dam and other cows
Authors: Waiblinger Susanne , Wagner Kathrin , Hillmann Edna , Barth Kerstin
Published: July 2020

The aim of the study reported in this Research Communication was to compare play behaviour and social interactions of dairy calves either separated from their mother and reared in a calf group (Artificial) or with access to their mother and the cow herd (cow-calf contact: Contact). Contact calves had access to a calf area and also to the cow barn where they could suckle their dam. Artificial calves were fed whole milk up to 16 kg per day via an automatic milk feeder and were only kept in the calf area. We observed the animals on 3 d during the first three months of life. Contact calves showed solitary play, consisting predominantly of locomotor play, for longer than Artificial calves and mainly in the cow barn. This indicates higher welfare in Contact calves. In addition, Artificial calves hardly experienced any agonistic interaction, while Contact calves both initiated and received agonistic interactions, which might contribute to the development of higher social competence.
Sensing solutions for improving the performance, health and wellbeing of small ruminants
Authors: Caja Gerardo , Castro-Costa Andreia , Salama Ahmed A.K. , Oliver Joan , Baratta Mario , Ferrer Carles , Knight Christopher H.
Published: July 2020

Diversity of production systems and specific socio-economic barriers are key reasons explaining why the implementation of new technologies in small ruminants, despite being needed and beneficial for farmers, is harder than in other livestock species. There are, however, helpful peculiarities where small ruminants are concerned: the compulsory use of electronic identification created a unique scenario in Europe in which all small ruminant breeding stock became searchable by appropriate sensing solutions, and the largest small ruminant population in the world is located in Asia, close to the areas producing new technologies. Notwithstanding, only a few research initiatives and literature reviews have addressed the development of new technologies in small ruminants. This Research Reflection focuses on small ruminants (with emphasis on dairy goats and sheep) and reviews in a non-exhaustive way the basic concepts, the currently available sensor solutions and the structure and elements needed for the implementation of sensor-based husbandry decision support. Finally, some examples of results obtained using several sensor solutions adapted from large animals or newly developed for small ruminants are discussed. Significant room for improvement is recognized and a large number of multiple-sensor solutions are expected to be developed in the relatively near future.
Integrative taxonomy reveals a cryptic species of the nudibranch genusPolycera(Polyceridae) in European waters
Authors: Sørensen Cecilie Gotaas , Rauch Cessa , Pola Marta , Malaquias Manuel António E.
Published: July 2020

This work aimed to test whether the colour variability featured by the European nudibranchPolycera quadrilineatais consistent with the concept of a single polychromatic species or may hide multiple lineages. Samples from across the geographic range ofP. quadrilineatatogether with representatives from worldwide species with a focus on Atlantic diversity, were gathered and studied using an integrative taxonomic approach. Morpho-anatomical characters were investigated by light and scanning electron microscopy. Bayesian molecular phylogenetics using MrBayes, the Automatic Barcode Gap Discovery species delimitation method, and haplotype network analysis using the PopArt software were employed to help delimit species using the mitochondrial gene cytochromecoxidase subunit I (COI). The results supported the existence of a second species, here described and namedPolycera norvegicasp. nov., only known from Norway where it is sympatric withP. quadrilineata. The COI uncorrectedp-genetic distance between the two species was estimated at 9.6–12.4%.Polycera norvegicasp. nov. differs by exhibiting a black dotted or patchy dotted pattern occasionally with more or less defined orange/brown patches, but never black continuous or dashed stripes as inP. quadrilineata. The two species share a common colouration with a whitish base and yellow/orange tubercles. Anatomically,P. norvegicasp. nov. has a weaker labial cuticle, a smaller radula with fewer rows, and only four marginal teeth, a reproductive system with a single lobed bursa copulatrix, shorter reproductive ducts, and a penis armed with two kinds of spines: needle-like and hook-shaped penile spines.
Infection with Toxoplasma gondii increases the risk of psychiatric disorders in Taiwan: a nationwide population-based cohort study
Authors: Lin Hsin-An , Chien Wu-Chien , Huang Kuo-Yang , Chung Chi-Hsiang , Chen Lih-Chyang , Lin Hsin-Chung , Guo Jong-Long
Published: July 2020

This study aimed to evaluate associations between toxoplasmosis and psychiatric disorders in Taiwan based on the National Health Insurance Research Database, Taiwan (1997–2013). Patients newly diagnosed with toxoplasmosis formed the case group (n = 259), and the control group included propensity-score matched patients without toxoplasmosis (n = 1036). The primary outcome was incidence of psychiatric disorders. Cox proportional hazards regression and stratified analyses were performed to examine risk of developing specific psychiatric disorders between patients with and without toxoplasmosis. Patients with toxoplasmosis had significantly higher incidence of psychiatric disorders than those without toxoplasmosis (P = 0.016). A significant difference was found in numbers of psychiatric disorders between the two groups during 14 years of follow-up (log-rank P < 0.001). Those with toxoplasmosis had significantly higher risk of bipolar disorder [adjusted hazard ratio (aHR = 3.60, 95% confidence interval (CI) = 2.07, 7.26), depression (aHR = 4.94, 95% CI = 2.15, 11.80) and anxiety (aHR = 5.36, 95% CI = 2.98, 25.88), but no significant between-group differences were found for schizophrenia and other psychiatric disorders. In conclusion, the present nationwide population-based analysis revealed that Toxoplasma gondii infection in Taiwan significantly increases the risk for developing bipolar disorder, depression and anxiety, but not for schizophrenia and other psychiatric disorders.
Morphometric and genetic evidence for cryptic diversity inGyrodactylus(Monogenea) infecting non-native European populations ofAmeiurus nebulosusandA. melas
Authors: Ondračková Markéta , Seifertová Mária , Bryjová Anna , Leis Eric , Jurajda Pavel
Published: July 2020

Gyrodactylid parasites were observed on non-native populations of North-American freshwater catfishes,Ameiurus nebulosusandAmeiurus melas(Siluriformes: Ictaluridae), at several sites in the Elbe River basin, Czech Republic, Europe. Using a combination of morphological and genetic analyses, the parasites infectingA. nebulosuswere determined to beGyrodactylus nebulosus, a North American parasite co-introduced to Europe along with itsAmeiurusfish hosts. Subtle morphometrical differences, as well as seasonal variations, were observed among parasites collected fromA. nebulosusandA. melas. The host-related variation was further supported through genetic analysis of the partial 18S rDNA, ITS1-5.8S-ITS2 and COI, showing 0.2, 3.0 and 4.8% divergence, respectively. Consistent genetic differences indicated there were two distinct genotypes. Subtle morphological differences associated with the shape of sickle toe, anchor root and ventral bar membrane, according to host species, also supported the description of a new cryptic species,Gyrodactylus melasn. sp., infectingA. melas. Multivariate morphometrical analysis of haptoral hard parts showed significant differences between the anchor lengths ofG. nebulosusandG. melasn. sp. However, the measurements of the haptoral hard structures partially overlapped between species, limiting the usage of these parameters for species delineation.
An efficient photograph-based quantitative method for assessing castrating trematode parasites in bivalve molluscs
Authors: Brian Joshua I. , Aldridge David C.
Published: July 2020

Parasitic castration of bivalves by trematodes is common, and may significantly reduce the reproductive capacity of ecologically important species. Understanding the intensity of infection is desirable, as it can indicate the time that has passed since infection, and influence the host's physiological and reproductive response. In addition, it is useful to know the developmental stage of the trematode, to understand trematode population trends and reproductive success. However, most existing methods (e.g. visually estimating the degree of infection) to assess intensity are approximate only and not reproducible. Here, we present a method to accurately quantify the percentage of bivalve gonad filled with digenean trematode tissue, based on small squashes of gonad tissue rapidly photographed under light microscopy. A maximum of 15 photographs is required to determine the percentage of the whole gonad occupied by trematodes with a minimum of 90% confidence, with smaller mussels requiring fewer. In addition, the stage of trematode infection can be assessed because full sporocysts, spent sporocysts and free cercariae are clearly distinguishable. Although variation exists in the distribution of trematodes in gonad tissue, and thus in the estimate of percentage of the gonad filled with trematodes, this method represents a marked improvement on current coarse assessments of infection which typically focus on binary presence/absence measures. This technique can be used to facilitate a more sophisticated understanding of host–parasite interactions in bivalves, and can inform the conservation and reproductive biology of environmentally crucial species.
Angiostrongylus cantonensis (rat lungworm) in Florida, USA: current status
Authors: Walden Heather D. S. , Slapcinsky John , Rosenberg Justin , Wellehan James F. X.
Published: July 2020

Angiostrongylus cantonensis has been found in Florida, USA, from the panhandle in the north to Miami and surrounding areas in the southern parts of the state, in both definitive and intermediate hosts in a limited studies completed in 2015. Additional studies have identified this parasite in a variety of intermediate hosts, both native and non-native gastropod species, with new host species recorded. Many areas in Florida with higher A. cantonensis prevalence were those with a high human population density, which suggests it is a matter of time before human infections occur in Florida. Case reports in the state currently involve non-human primates and include a gibbon and orangutan in Miami. Here, we report the current status of A. cantonensis in the state, as well as the infection in a capuchin monkey and presumptive infection in a red ruffed lemur in Gainesville, Florida.
The Role of Environmental Factors in the Early Development of Egyptian Stone Architecture
Authors: Wong Jun Yi
Published: July 2020

Much detail regarding the early development of stone architecture in Egypt remains unclear. Prevailing studies tend to focus on the contribution of religious and socio-economic factors, but the role of environmental elements should not be understated. For much of the First Dynasty, innovation in stone architecture was driven by developments in the private realm, a result of favourable geology in Lower Egypt. Meanwhile, multiple strands of evidence suggest that Egypt experienced wetter climatic conditions during the Early Dynastic period and the Old Kingdom. This would have had major implications on both the production of mudbrick and the short-term durability of mudbrick structures. It is argued that these environmental factors played a key role in facilitating and accelerating the rise of stone architecture in Egypt.
A national study of the outcome after treatment of critical aortic stenosis in the neonate
Authors: Kjellberg Olofsson Cecilia , Hanseus Katarina , Johansson Ramgren Jens , Johansson Synnergren Mats , Sunnegårdh Jan
Published: July 2020

Objective:

This study describes short-term and long-term outcome after treatment of critical valvular aortic stenosis in neonates in a national cohort, with surgical valvotomy as first choice intervention.

Methods:

All neonates in Sweden treated for critical aortic stenosis between 1994 and 2016 were included. Patient files were analysed and cross-checked against the Swedish National Population Registry as of December 2017, giving complete survival data. Diagnosis was confirmed by reviewing echo studies. Critical aortic stenosis was defined as valvular stenosis with duct-dependent systemic circulation or depressed left ventricular function. Primary outcome was all-cause mortality and secondary outcomes were reintervention and aortic valve replacement.

Results:

Sixty-one patients were identified (50 boys, 11 girls). Primary treatment was surgical valvotomy in 52 neonates and balloon valvotomy in 6. Median age at initial treatment was 5 days (0–26), and median follow-up time was 10.8 years (0.14–22.6). There was no 30-day mortality but four late deaths. Freedom from reintervention was 66%, 61%, 54%, 49%, and 46% at 1, 5, 10, 15, and 20 years, respectively. Median time to reintervention was 3.4 months (4 days to 17.3 years). Valve replacement was performed in 23 patients (38%).

Conclusions:

Surgical valvotomy is a safe and reliable treatment in these critically ill neonates, with no 30-day mortality and long-term survival of 93% in this national study. At 10 years of age, reintervention was performed in 54% and at end of follow-up 38% had had an aortic valve replacement.
Contingent hope theory: The developmental exploration of hope and identity reconciliation among young adults with advanced cancers
Authors: Currin-McCulloch Jennifer , Walsh Casey , Gulbas Lauren , Trevino Kelly , Pomeroy Elizabeth , Jones Barbara
Published: July 2020

Objective

The diagnosis of an advanced cancer in young adulthood can bring one's life to an abrupt halt, calling attention to the present moment and creating anguish about an uncertain future. There is seldom time or physical stamina to focus on forward-thinking, social roles, relationships, or dreams. As a result, young adults (YAs) with advanced cancer frequently encounter existential distress, despair, and question the purpose of their life. We sought to investigate the meaning and function of hope throughout YAs’ disease trajectory; to discern the psychosocial processes YAs employ to engage hope; and to develop a substantive theory of hope of YAs diagnosed with advanced cancer.

Method

Thirteen YAs (ages 23–38) diagnosed with a stage III or IV cancer were recruited throughout the eastern and southeastern United States. Participants completed one semi-structured interview in-person, by phone, or Skype, that incorporated an original timeline instrument assessing fluctuations in hope and an online socio-demographic survey. Glaser's grounded theory methodology informed constant comparative methods of data collection, analysis, and interpretation.

Results

Findings from this study informed the development of the novelcontingent hopetheoretical framework, which describes the pattern of psychosocial behaviors YAs with advanced cancer employ to reconcile identities and strive for a life of meaning. The ability to cultivate the necessary agency and pathways to reconcile identities became contingent on the YAs’ participation in each of the psychosocial processes of the contingent hope theoretical framework: navigating uncertainty, feeling broken, disorienting grief, finding bearings, and identity reconciliation.

Significance of Results

Study findings portray the influential role of hope in motivating YAs with advanced cancer through disorienting grief toward an integrated sense of self that marries cherished aspects of multiple identities. The contingent hope theoretical framework details psychosocial behaviors to inform assessments and interventions fostering hope and identity reconciliation.
Where Are the Women? Descriptive Representation and COVID-19 in U.K. Daily Press Briefings
Authors: Smith Jessica C.
Published: July 2020

As governments tackle the ongoing COVID-19 pandemic, both the role of women in governments and the specific effect of the pandemic on women have come under scrutiny. This research note examines the descriptive representation of women in the U.K. government's response to the coronavirus. It finds that 43% of the government's daily press briefings featured an all-male lineup with no female politician or expert present. In particular, female politicians are missing, with only one female cabinet member ever leading the briefing. Women's (in)visibility raises concerns about the legitimacy of democratic decisions and likely has policy consequences: women's absence may exacerbate gendered inequalities resulting from the crisis.
Design of a miniature dual-band bandpass filter with interlocked stepped-impedance resonators for 5G new radio access technology
Authors: Hsu Wei-Lun , Lyu Pei-Yu , Chang Sheng-Fuh
Published: July 2020

A miniature dual-band bandpass filter with interlocked stepped-impedance resonators (SIRs) is presented in this paper, which was designed for the student design competition held in European Microwave Week 2019. This bandpass filter is required to have two concurrent passbands, namely, the first passband at 900–1000 MHz and the second passband at 1427–1518 MHz bands, which cover six designated bands in sub-6 GHz range of fifth generation (5G) New Radio Access Technology. Three stopbands are required at 500–850, 1050–1350, and 1600–2000 MHz, respectively. To achieve the best figure of merit, an interlocked configuration of two SIRs is proposed. One advantage is that the impedance ratio of the inter-locked SIR can be controlled to have two passbands at the required frequencies. Second, the coupling section of the interlocked SIR gives three transmission zeros distributed to every stopbands such that the stopband suppression are dramatically enhanced. The measured results show that the passband insertion losses are 2.16 dB at the first passband and 1.33 dB at the second passband, and the return losses are greater than 10 dB. The stopband suppression at the transmission zeros are greater than 38 dB. The circuit is very compact as 41.40 × 19.96 mm2, equivalent to $0.25 \times 0.12\,\lambda _g^2$.
Protecting the right to life in protracted conflicts: The existence and dignity dimensions of General Comment 36
Authors: Rishmawi Mona
Published: July 2020

With a focus on situations of protracted conflict, this article explores the new horizons offered by the recent explanation by the United Nations Human Rights Committee on the right to life in its General Comment 36. The freshly formulated contours of this right not only present normative clarity but are also valuable for conflict management and resolution. Considering the articulation by the Human Rights Committee, we can now see two dimensions of this right: existence and dignity. Although the existence dimension is not new, one now finds additional insights concerning the legality, transparency and accountability of the use of lethal force that have particular relevance to armed conflict. The new dignity dimension has practical implications for the conditions of life in protracted conflicts, taking us beyond norms to the policy spheres of humanitarian action and development. Tracing the origins of the term “protracted conflict” to the late Lebanese scholar Edward Azar, the article also introduces the reader to some of his work and thinking.
Bouncing Back from the Burden of Dementia
Authors: Wuttke-Linnemann Alexandra , Henrici Clara Blanca , Müller Norbert , Lieb Klaus , Fellgiebel Andreas
Published: July 2020

Abstract. Background: Although there is mounting evidence of dyadic interdependencies between patients with dementia (PWD) and their caregivers, predictors of resilience among PWD and their caregivers are generally regarded in isolation. We therefore investigated how dyadic interdependencies regarding common resilience factors predict subjective notions of individual resilience. Methods: A total of 29 dyads (caregivers: 23 female, 73 ± 7 years; PWD: 6 female, 76 ± 6 years, Mini-Mental State Examination (MMSE) score: 18 ± 6) drawn from two studies answered questions about resilience (Brief Resilience Scale; BRS), partnership quality (Marital Quality Questionnaire; PFB), and depression (Geriatric Depression Scale; GDS-15). Using linear regression models, we predicted BRS scores by linearly combining individual characteristics (intraindividual level), characteristics of the partner (interindividual level), and their dyadic similarity (dyadic level). Results: Intraindividually, higher resilience in caregivers was associated with female sex; interindividually, it was associated with lower MMSE scores and higher PFB scores in PWD. On a dyadic level, the more different the GDS-15 scores were, the higher the resilience of caregivers. For PWD, higher resilience was significantly related to individual lower GDS-15 scores and higher PFB scores, while the characteristics of caregivers did not explain any variance. However, similarity in GDS-15 scores predicted higher resilience in PWD. Discussion: Resilience is affected differently in PWD and caregivers, potentially pointing to different strategies in coping with disease-related changes. Future studies are necessary to examine the mechanisms underlying resilience in PWD and their respective caregiver in order to tailor interventions that address the needs of both parties, from the individual, interindividual, and dyadic perspectives.
Balancing Between Goal-Directed and Habitual Responding Following Acute Stress
Authors: Hartogsveld Bart , van Ruitenbeek Peter , Quaedflieg Conny W. E. M. , Smeets Tom
Published: July 2020

Abstract. Instrumental learning is regulated by two memory systems: a relatively rigid but efficient habit system and a flexible but resource-demanding goal-directed system. Previous work has demonstrated that exposure to acute stress may shift the balance between these systems toward the habitual system. In the current study, we used a 2-day outcome devaluation paradigm with a 75% reward contingency rate and altered food reward categories to replicate and extend our previous findings. Participants learned neutral stimulus–response–reward associations on the first day. On the second day, rewards were devalued by eating to satiety. Subsequently, acute stress was induced in half of the participants using the Maastricht Acute Stress Test, while the other half engaged in a nonstressful control task. Finally, relative goal-directed versus habitual behavior was evaluated in a slips-of-action phase, where more slips-of-action indicate a shift toward the habitual system. Results showed that participants successfully acquired the stimulus–response–reward associations, that devaluation was effective, and that stressed participants displayed significant increases in cortisol and blood pressure. Stress led participants to commit more slips-of-action compared with nonstressed controls. The current study extends previous work, showing that the employed paradigm and outcome devaluation procedure are boundary conditions to the stress-induced shift in instrumental responding.
Seasonal Variation of Wet Deposition of Black Carbon in Arctic Alaska
Authors: Mori T. , Kondo Y. , Ohata S. , Zhao Y. , Sinha P. R. , Oshima N. , Matsui H. , Moteki N. , Koike M.
Published: July 2020

Black carbon (BC) aerosol deposited in and onto Arctic snow increases the snow's absorption of sunlight and accelerates snowmelt. Wet removal of BC from the atmosphere plays a key role in determining its abundance in the Arctic atmosphere and in Arctic snow. However, this process is poorly understood, mainly due to the scarcity of relevant measurements. To study wet deposition of BC, we made measurements of mass concentration of BC in snow and rain (CMBC) and of BC in air (MBC) with high accuracy (16% and 10%, respectively) at the Barrow Atmospheric Baseline Observatory, Alaska, from July 2013 to August 2017 and analyzed them along with routinely measured meteorological parameters from Barrow. Monthly mean MBC near the surface and CMBC were poorly correlated from midwinter to early spring, when CMBC was close to the annual median while MBC was at its annual peak. Seasonal variations in the altitude distribution of MBC may lead to these differences in seasonal variation of MBC near the surface and CMBC. About 50% of the annual wet deposition of BC occurred in the 3 months of summer, associated with high values of total precipitation and BC originating from biomass burning. Size distributions of BC in snow and rain were stable throughout the year, suggesting that the size distribution of BC in the lower troposphere was similarly stable. Calculations by two global models reproduced the observed seasonal variations of CMBC and showed that BC from biomass burning dominated CMBC in summer.
Advanced Newton Methods for Geodynamical Models of Stokes Flow With Viscoplastic Rheologies
Authors: Rudi Johann , Shih Yu‐hsuan , Stadler Georg
Published: July 2020

Strain localization and resulting plasticity and failure play an important role in the evolution of the lithosphere. These phenomena are commonly modeled by Stokes flows with viscoplastic rheologies. The nonlinearities of these rheologies make the numerical solution of the resulting systems challenging, and iterative methods often converge slowly or not at all. Yet accurate solutions are critical for representing the physics. Moreover, for some rheology laws, aspects of solvability are still unknown. We study a basic but representative viscoplastic rheology law. The law involves a yield stress that is independent of the dynamic pressure, referred to as von Mises yield criterion. Two commonly used variants, perfect/ideal and composite viscoplasticity, are compared. We derive both variants from energy minimization principles, and we use this perspective to argue when solutions are unique. We propose a new stress‐velocity Newton solution algorithm that treats the stress as an independent variable during the Newton linearization but requires solution only of Stokes systems that are of the usual velocity‐pressure form. To study different solution algorithms, we implement 2‐D and 3‐D finite element discretizations, and we generate Stokes problems with up to 7 orders of magnitude viscosity contrasts, in which compression or tension results in significant nonlinear localization effects. Comparing the performance of the proposed Newton method with the standard Newton method and the Picard fixed‐point method, we observe a significant reduction in the number of iterations and improved stability with respect to problem nonlinearity, mesh refinement, and the polynomial order of the discretization.
Improving the Noah‐MP Model for Simulating Hydrothermal Regime of the Active Layer in the Permafrost Regions of the Qinghai‐Tibet Plateau
Authors: Li Xiangfei , Wu Tonghua , Zhu Xiaofan , Jiang Yingsha , Hu Guojie , Hao Junming , Ni Jie , Li Ren , Qiao Yongping , Yang Cheng , Ma Wensi , Wen Amin , Ying Xue
Published: July 2020

Soil hydrothermal regime of the active layer in the permafrost regions of the Qinghai‐Tibet Plateau (QTP) is important to the underlying permafrost and the climate change dynamics in Asia. However, a large bias still exists in current land surface models in the representation of soil temperature and moisture. This study assessed and augmented the Noah land surface model with multiparameterization options (Noah‐MP) for simulating soil hydrothermal dynamics at the Tanggula (alpine meadow) and Beiluhe (alpine swamp) stations located in the permafrost regions of the QTP. The results showed that the default Noah‐MP tended to underestimate soil temperature and moisture. Specifically, the default model overestimated the snow depth and duration due to the low snow sublimation rate. This resulted in a cold deviation in the soil temperature at two stations. Such underestimation was reduced by introducing a scheme that considered the sublimation loss from wind. Moreover, the remaining cold bias in the soil profiles of two stations was greatly resolved by a combined scheme of roughness length for heat (Z0h) and undercanopy aerodynamic resistance (ra,g). A soil thermal conductivity scheme, which can produce more realistic soil thermal conductivity in frozen soil, further improved the deep soil temperature simulation. The consideration of soil organic matter could mitigate the underestimation of the shallow soil moisture to some extent, but this improvement was more obvious at the Tanggula station, which had coarser mineral soil than the Beiluhe station.
An Observational Comparison of Level of Neutral Buoyancy and Level of Maximum Detrainment in Tropical Deep Convective Clouds
Authors: Wang Dié , Jensen Michael P. , D'Iorio Jennifer A. , Jozef Gina , Giangrande Scott E. , Johnson Karen L. , Luo Zhengzhao Johnny , Starzec Mariusz , Mullendore Gretchen L.
Published: July 2020

Tropical deep convective clouds are important drivers of large‐scale atmospheric circulation representing the main vertical transport pathway through the depth of the troposphere for heat, momentum, water, and chemical species. The strength and depth of this transport are impacted by the convective updraft size and intensity that are driven by buoyancy, dynamical forcing, and mixing of environmental air, that is, entrainment. In this study, we identify tropical deep convective systems with well‐defined forward anvils using Atmospheric Radiation Measurement (ARM) ground‐based profiling radars, at three ARM fixed sites in the Tropical Western Pacific (TWP; i.e., Manus, Nauru, and Darwin) and three ARM Mobile Facility deployments in Niamey, Niger; Gan Island, Maldives; and Manacapuru, Brazil. We use the difference between the level of neutral buoyancy (LNB) and the level of maximum detrainment (LMD) as a proxy for the effective bulk convective entrainment (εproxy). The LNB, the theoretical height that a parcel raised above the level of free convection would reach with no mixing, is calculated based on preconvection radiosonde measurements using parcel theory. The LMD is the height of the maximum reflectivity observed in forward anvil clouds by profiling radars. Deep convective systems over the TWP show higher LNBs that extend to 16.3 km on average and largerεproxy(median value of LNB minus LMD up to 6.5 km) compared to their continental counterparts in the Amazon and West Africa. Oceanic conditions show larger convective available potential energy (CAPE) coupled with higher moisture at low levels, which favors largerεproxy. In contrast, continental cases initiate and develop, under high convective inhibition, steeper environmental lapse rate, and high wind shear conditions, which show smaller offset between LNB and LMD. Deep convective cases that promote significant cold pools at the surface experience lessεproxy. Using a Random Forest regression algorithm, CAPE is associated with the highest feature importance score for predicting convectiveεproxy, followed by low‐level relative humidity. For continental cases, the low‐level wind shear also indicates higher importance.