bluuebunny/crossref_metadata_2025 huggingface dataset:
Contribuições do Material Dourado para o ensino de números decimais numa turma do 6º ano do Ensino Fundamental II
Authors: Ferrugine Samira Santos , Evangelista Dilson Henrique Ramos , Evangelista Cristiane Johann
Published: April 2021

Apresentamos neste trabalho, uma experiência com uso do Material Dourado e Quadro do Valor de Lugar (QVL) em aulas de Matemática na Escola Municipal de Ensino Fundamental Irmão Pio Barroso. O objetivo do estudo foi investigar as contribuições do uso do Material Dourado e QVL no ensino do sistema decimal de numeração, em especial a representação dos números decimais em uma turma de 6º ano. As atividades investigativas com material didático visaram a construção e fortalecimento dos conhecimentos prévios que os alunos adquiriram em anos anteriores dando sequência em conteúdos posteriores relacionados às operações fundamentais e números decimais. Desenvolveu-se um estudo qualitativo do tipo Pesquisa-ação a partir de uma problemática vivenciada na prática docente em relação ao ensino de números decimais. Os instrumentos de pesquisa foram o diário de campo da pesquisadora, questionário e material produzido pelos alunos. Destaca-se como resultados as contribuições vivenciadas pelos alunos relacionadas à participação na aula, interação com os colegas, socialização de dúvidas e verbalização de conceitos relacionados à representação de números decimais. O estudo contribui para o campo da educação matemática ao evidenciar o potencial do Material Dourado e QVL para o estudo de números decimais em turmas de 6º ano e sugere-se a realização de novas pesquisas.
Aromatic compounds in bitumoids of the Bazhenov Formation in the North of the Khantey hemiantheclise
Authors: Sotnich Inga S. , Kostyreva Elena A.
Published: April 2021

The main features of the geochemistry of individual aromatic compounds (phenanthrenes, dibenzothiophenes, mono- and triaromatic steroids) in chloroform extracts (bitumoids) from the open (regular form and coarse-crushed (≥0.5 cm) samples) and closed (fine-crushed (0.25 mm) samples) pore space of the Bazhenov Formation have been determined. The differences in the aromatic compounds distribution of organic matter of the Bazhenov Formation in the North of the Khantey hemiantheclise (Surgut region, Khanty-Mansiysk Autonomous District, Western Siberia) are mainly related to its stage of thermal maturity which decreases in the south-west direction within the studying area. The most sensitive to maturity variations at the same catagenesis gradation are the parameters: CPI, Ts/Tm, 1/Ki ((n-C17 + n-C18)/(Pr + Ph)), MDR (4-MDBT/1-MDBT), DBTI ((2+3-MDBT)/DBT) and TASI (TAS I/(TAS I + TAS II)). Based on some indicators (PI, MPI, PP-1, MDR, DBTI etc.), it is possible to notice the decrease and equalization of its values in bitumoids from closed pores compared with those from open ones. It seems to be associated with the removal of the most transformed, light and migratory-capable part of bitumoids during their extraction from the open pore space of rocks.
Seismogeological structure model of the Anabar-Olenek region
Authors: Gubin Igor A. , Kontorovich Vladimir A.
Published: April 2021

The velocity characteristics of the Upper Proterozoic-Phanerozoic sedimentary cover of the Anabar-Olenek region were studied, in particular, the bimodal character of the distribution interval P-wave velocities was established. Taking into account modern ideas about the chronostratigraphy of sediments encountered by the Charchykskaya-1, Burskaya-3410 and Khastakhskaya-930 deep boreholes, stratification of reflecting horizons was carried out and time sections from previous years were reinterpreted. From the perspective of seismic stratigraphic and seismic facies analysis, the Cambrian, Vendian, and Riphean intervals of the section were examined in detail. In the course of the analysis, adjustments to the stratigraphic breakdown of the Burskaya-3410 and Charchykskaya-1 boreholes are proposed. The study shows that the Lapar Formation, which underwent Prepermian erosion, increase in the thickness multiple in an eastward direction. The distribution areas of the Tuessal Formation, the Lower and Middle Cambrian clinoform complex, as well as the areas of the Upper Riphean Formations reaching the Prevendian erosion surface are contoured. An Intrariphean tectonic disagreement between the Kulady Formation and older deposits was established.
Geology, physical-chemical and geodynamic conditions for the formation of Sokolovsk and Krasnokamensk granitoid massifs (South Ural)
Authors: Snachev Vladimir I. , Snachev Aleksandr V. , Puzhakov Boris A.
Published: April 2021

The article describes the geological structure of the Sokolovsk and Krasnokamensk massifs located in the central part of the Western subzone of the Chelyabinsk-Adamovka zone of the Southern Urals. They are of Lower Carboniferous age and break through the volcanogenic-sedimentary deposits of the Krasnokamensk (D3kr) and Bulatovo (S1-D1bl) strata. It was found that these intrusions belong to the gabbro-syenite complex and are composed of gabbroids (phase I) and syenites, quartz monzonites, less often monzodiorites (phase II). The rocks of the second phase predominate (90–95%). Gabbros belong to the normal alkaline series of the sodium series and are close to tholeiitic mafic rocks, the formation of which is associated with riftogenic structures; syenites correspond to moderately alkaline series with K-Na type of alkalinity. It has been proved that in terms of their petrographic, petrochemical, geochemical, and metallogenic features (content of TiO2, K2O, Na2O, Rb, Sr, distribution of REE, the presence of skarn-magnetic mineralization), the rocks of the massifs under consideration undoubtedly belong to the gabbro-granite formation. Crystallization of the Sokolovsk and Krasnokamensk intrusions occurred at a temperature of 880–930 °С in the mesoabyssal zone at a depth of about 7–8 km (P = 2.2–2.4 kbar). At the postmagmatic stage, the transformation parameters of the initially igneous rocks were, respectively, T = 730–770 °C, P = 4.0–4.2 kbar. The fact that these massifs belong to the gabbro-granite formation makes it possible to include them, together with Bolshakovsk, Klyuchevsky, Kurtmaksky and Kambulatovo, into the Chelyabinsk-Adamovka segment of the South Ural Early Carboniferous rift system.
DEMOCRACIA EM PERSPECTIVA: UM CONTRAPONTO ATUAL ENTRE AS TRAJETÓRIAS DE MODERNIDADE BRASILEIRA, SUL-AFRICANA E EUROPEIA

DEMOCRACY IN PERSPECTIVE: A CURRENT COUNTERPOINT BETWEEN BRAZILIAN, SOUTH AFRICAN AND EUROPEAN MODERNITY TRAJECTORIES
Authors: Gotlib Joyce
Published: April 2021

Resenha sobre a obra: "Collective Actions and Political Transformations: The entangled experiences in Brazil, South Africa and Europe", dos autores Aurea Mota e Peter Wagner.
O BRASIL COMO “TERRENO DE EXPERIMENTAÇÃO” DA EXPERTISE GERENCIAL: A ATUAÇÃO DO CONSELHO DE REITORES DAS UNIVERSIDADES BRASILEIRAS (1966-1985)

BRAZIL AS A "LABORATORY" FOR MANAGEMENT EXPERTISE: THE ROLE OF THE BOARD OF DIRECTORS OF BRAZILIAN UNIVERSITIES (1966-1985)
Authors: Carlotto Maria Caramez , Garcia Sylvia Gemignani
Published: April 2021

Na literatura contemporânea sobre as transformações do ensino superior existe um forte consenso de que a expansão do saber gerencial foi um dos principais fatores que alterou sua dinâmica e organização interna. No caso do Brasil, são muitos os trabalhos que, seguindo essa percepção geral, apontam a estreita relação existente entre as políticas ditas “neoliberais” implementadas a partir da década de 1980, e a modernização gerencial difundida no país a partir de acordos de cooperação com os EUA durante os anos 1950 e 1960. No entanto, esses trabalhos, de modo geral, falham ao não conseguir mostrar, empiricamente, como se dá a relação entre esses dois momentos da história das políticas educacionais do país. O objetivo do presente trabalho é contribuir para a compreensão dessa relação a partir da análise de Yves Dezalay e Brynat Garth sobre o modo pelo qual a América Latina funcionou, nos anos 1950 e 1960, enquanto um “terreno de experimentação” de políticas que viriam a se difundir mundialmente nos anos 1980 e 1990. Para tanto, tomamos como objeto o Conselho de Reitores de Universidades Brasileiras (CRUB), no período que vai de 1966, ano da sua criação, até 1985, ano que marca o fim do regime militar, analisando tanto o conjunto de acordos internacionais então firmados pelo CRUB, quanto o resumo das suas principais atividades, e o perfil da sua diretoria executiva no período analisado.ABSTRACT In the contemporary literature on the transformations of higher education there is a strong consensus that the expansion of managerial knowledge was one of the main factors that altered its dynamics and internal organization. In the case of Brazil, there are many studies that, following this general perception, point to the close relationship between the so-called “neoliberal” policies implemented since the 1980s and the managerial modernization diffused in the country through cooperation agreements with the USA during the 1950s and 1960s. However, these works generally fail to show the relationship between these two moments in the history of educational policies in the country empirically. The objective of the present work is to contribute to the understanding of this relationship using, as a starting point, the analysis of Yves Dezalay and Brynat Garth on how Latin America functioned in the 1950s and 1960s as a “laboratory” of policies that would begin to spread worldwide in the 80s and 90s. To this end, we investigate the Council of Rectors of Brazilian Universities (CRUB) in the period from 1966, the year of its creation, until 1985, the year that marks the end of the military regime, analyzing both the set of international agreements signed by the CRUB during the period as well as the summary of its main activities and the profile of its executive board in this period of time.
The Good, the Bad and the Right: Formal Reductions among Deontic Concepts
Authors: Glavaničová Daniela , Pascucci Matteo
Published: April 2021

The present article provides a taxonomic analysis of bimodal logics of normative ideality and normative awfulness, two notions whose meaning is here explained in terms of the moral values pursued by a given community. Furthermore, the article addresses the traditional problem of a reduction among deontic concepts: we explore the possibility of defining other relevant normative notions, such as obligation, explicit permission and Hohfeldian relations, in terms of ideality and awfulness. Some proposals in this respect, which have been formulated in the literature over the years, are here improved and discussed with reference to the various logics that we will introduce.
Tableau Systems for Epistemic Positional Logics
Authors: Klonowski Mateusz , Krawczyk Krzysztof Aleksander , Pięta Bożena
Published: April 2021

The goal of the article is twofold. The first one is to provide logics based on positional semantics which will be suitable for the analysis of epistemic modalities such as ‘agent ... knows/beliefs that ...’. The second one is to define tableau systemsfor such logics. Firstly, we present the minimal positional logic MR. Then, we change the notion of formulas and semantics in order to consider iterations of the operator of realization and “free” classical formulas. After that, we move on to weaker logics in order to avoid the well known problem of logical omniscience. At the same time, we keep the positional counterparts of modal axioms (T), (4) and (5). For all of the considered logics we present sound and complete tableau systems.
A City Full of Life or a City Buried Alive? Vittorio Alfieri’s Venice and Venice in the Travel Journals by Polish Artists at the Turn of the 19th Century
Authors: Szadkowska-Mańkowska Olga
Published: April 2021

The article raises the topic of the evolving image of Venice from the perspectives of three travel accounts: by Vittorio Alfieri, Fryderyk August Moszyński, and Stanisław Dunin-Borkowski. They were all bound by the figure of the Italian playwright Alfieri. In the article, I propose a new look into the accounts from the travels of Polish intellectual elite: an enlightened journey described in the recollections by Moszyński, and a 19th-century journey depicted in the journals by Borkowski, following Alfieri as the guide. Considering his tragedies in support of national liberation, he perfectly matched the ideas in the minds of Polish artists at the turn of the 19th century. Even though the author may be forgotten today, the reception of his works, depending on the historical period, political situation, and literary streams, evolved interchangeably placing him in the spotlight and ignoring him. In the first half of the 19th century, he was a significant figure, a fact which triggers interesting observations, particularly in the context of the journeys of artists to Venice.
“Literally, there were only a few steps between the cold and warmth, and between darkness and light.” The Image of the City in "Smutna Wenecja" by Wacław Kubacki
Authors: Kuran Magdalena
Published: April 2021

The article discusses the image of the city presented in the novel Smutna Wenecja by Wacław Kubacki, an outstanding literary historian, and how the writer’s interests and experiences influenced the topic and the character of the work (he utilised his journals). The city depicted by Kubacki seems to possess a dichotomous nature. The Venetian garden of the arts and the mecca of academics was contrasted with the Venice of poor and foul recesses. The author contrasted the Venice of tourists’ “unbridled excess” with the reality of the life of Venice’s proletariat. The article indicates the linguistic and compositional means which the writer used to reflect that duality, beauty, and ugliness. The article also indicates the dominant features of the novel, i.e. intellectualism and sensoriness.
Venice in Films. "Wenecja" by Jan Jakub Kolski (2010)
Authors: Grodź Iwona
Published: April 2021

The topic of the article is the image of Venice in Wenecja, a Polish feature film direc­ted by Jan Jakub Kolski from 2010. The imaginary image of this city was inspired by “Sezon w Wenecji” (from the volume titled Jedźmy, wracajmy..., Krakow 1993 or Jedźmy, wracajmy i inne opowiadania, Warsaw 2000), a literary text by Włodzimierz Odojewski (1930–2016).  The article undertakes to analyse the image of Venice in the film by the author of Historia kina w Popielawach as a testimony of understanding its role in a particular historical space and time, of both the plot of the film and the projected reception.
Venice in Poetry and Prose: Adam Wiedemann’s Visit to the City
Authors: Czyżak Agnieszka
Published: April 2021

The main aim of the article is to identify key interpretation issues in two texts by Adam Wiedemann. Both texts feature contemporary literary pictures of visits to Venice – the Polish author wrote a short story (Sens życia. Opowiadanie śródziemnomorskie, 1998) and a poem (Tramwaj na Lido, 2015) about his journeys to Italy. Those textual visions of the urban space of Venice show that Wiedemann is fully aware of many similar attempts made earlier yet still strives to stress his distinctness, creating a record of meetings of the contemporary visitor with the unique phenomenon of the unusual urban phenomenon.
Form and Power On the Disciplinary Coding of National Identity in “Pamiętnik Stefana Czarnieckiego” by Witold Gombrowicz
Authors: Jativa Tomasz
Published: April 2021

The aim of this article is to analyse Witold Gombrowicz’s short story entitled “Pamiętnik Stefana Czarnieckiego” in the context of the convergence between the writer’s worldview and the philosophy of Michel Foucault. Nietzschean motifs inspired both authors to formulate a similar constructivist anthropology and a similar criticism of the concept of discipline. The themes of form and creating a human being by a human being – central to Gombrowicz’s writing – correspond to Foucault’s notion of the production of the subject. In such a perspective, “Pamiętnik Stefana Czarnieckiego” can be read as a record of the experience of an individual subjected to social practices of disciplinary embarrassment, aimed at producing a subject defined by nationality and heteronormativity, as well as the experience of rebellion against an imposed identity. Such a reading reveals the political stakes of the literary output by the author of Ferdydurke: expressed in the deconstruction of authoritarian forms of empowerment and in the pursuit to replace them with forms of subjectification based on irony, fluidity and distance.
“A Production Center”: A Model of Creative Work in Tadeusz Konwicki’s Early Prose
Authors: Miernecka Martyna
Published: April 2021

The aim of this article is to outline the issues related to the specificity of the image of the writer and his role in society created in Tadeusz Konwicki’s early works. This stage in the writer’s life opens with the first short story that Konwicki published, namely “Kapral Koziołek i ja” from 1947, after which the initial model of his writing is subject to gradual erosion and ends between 1954 and 1955 with the novel titled Z oblężonego miasta. Investigating the motif of the creative work house on the basis of Z oblężonego miasta is a pretext for reflection on the category of the writer’s work. The article traces the motifs of the professional category of the writer, through analysing the constructions on which Konwicki’s narratives are based. At the same time, due to the analysis of social discourse in which the author participated, the article outlines the social functions he performed at a given time.
"Kwiaty polskie" by Julian Tuwim as a Reflection on Law, the Political System, and the State
Authors: Kijowski Maciej
Published: April 2021

Kwiaty Polskie by Julian Tuwim a multi-thread multifaceted masterpiece. The author of the article discusses it through the prism of legal and political content identifiable in the text without omitting references to the state and its system in Tuwim’s earlier works, and indicates the way in which the short-term student of law school perceived and experienced law. The superb boyish laws are the fragment of Kwiaty Polskie which the author analysed in terms of the legislative technique.
Barriers to Hiring and Accommodating People With Disabilities in Small and Medium Sized Businesses: A Scoping Review
Authors: Sepulveda Theresa
Published: April 2021

Research has found that small and medium sized businesses are less likely to hire, retain and offer job accommodations to people with disabilities than larger companies. Since small to midsize businesses employ almost half of the nation's workforce, this may be an underutilized source of employment for people with disabilities. A scoping literature review using Arksey and O'Malley's framework (Arksey, H., & O'Malley, L. [2005]. Scoping studies: Towards a methodological framework. International Journal of Social Research Methodology, 8(1), 19–32. https://doi.org/10.1080/1364557032000119616) was used to investigate two questions: What are the barriers to hiring individuals with disabilities in small and medium sized businesses? And what are the barriers to job accommodations and retention of individuals with disabilities in small and medium sized businesses? Five themes emerged; cost associated with hiring and accommodating, stereotypes/stigma, employer policies and practices, engagement with rehabilitation service agencies, and Americans with Disabilities Act (ADA)/disability legislation. The findings uncovered several barriers. Small and medium sized businesses were more likely to be concerned about costs, less likely to engage in rehabilitation services, and have diversity policies in place and had less favorable attitudes toward people with disabilities and ADA legislation. Limitations, and implications for rehabilitation counseling, and future research are discussed.
Effective Job Supports to Improve Employment Outcomes for Individuals With Autism Spectrum Disorder
Authors: Seagraves Kayli
Published: April 2021

The unemployment rate of those with autism spectrum disorder (ASD) is staggeringly high. The low number of those with ASD in the competitive workforce can be connected to the complex and sometimes severe manifestations of the disorder. However, there are many supports and accommodations that individuals with ASD can use in order to alleviate the stress of finding and maintaining competitive employment. Natural supports can be provided through supportive supervisors, informed coworkers, and on-the-job trainings. Vocational rehabilitation services are provided in order to assess, prepare, and support individuals with ASD through their employment. Lastly, job modifications are used to alleviate any stressors that an employee with ASD may experience on the job. The current literature found that natural supports, vocational rehabilitation services, and job modifications were effective in improving the employment outcomes for individuals with ASD. Rehabilitation counselors can use the information found in this literature review to inform employers of successful and effective job supports for employees with ASD.
Understanding Acute Care Usage by Adult Chronically Critically Ill Ventilated Patients: A Chart Review
Authors: Crowe Sarah , Howard A. Fuchsia , Haljan Gregory
Published: April 2021

Objectives: To better understand the rationale for acute care usage among long term care ventilated residents. Background: Chronically critically ill ventilated individuals experience complex health challenges, with many not surviving one year post initial hospitalization discharge. Recent research reports high acute care readmission rates for chronically critically ill patients, yet most studies have not examined the reasons patients are readmitted, nor the treatment and care provided during these stays. Method: A retrospective medical chart reviews of all emergency department visits and acute care admissions, occurring from August 2014 to August 2016, of chronically critically ill ventilated individuals living in a residential care facility in the province of British Columbia, Canada was conducted. Results: There were 49 emergency department visits and 56 acute care admissions over a 2 year period by 20 chronically critically ill ventilated residential care patients. The majority of acute care admissions were related to pneumonia, whereas the majority of emergency department visits were not specified. Conclusion: Chronically critically ill ventilated long term care residents are high users of acute care resources, frequently admitted for pneumonia.
Review of methodological approaches to the analysis of the transformation of the agricultural labor market in modern Russia
Authors: Mukhanova Maria N.
Published: April 2021

The article provides an overview and generalization of Russian studies of the transformation of the agricultural labor market in the post-Soviet period. Researchers of the Russian countryside reflect the obtained results in publications mainly describing the problems associated with the Russian countryside and the agricultural labor market. This is, first of all, the destruction of the rural infrastructure, poverty, unemployment, the interaction of old and new production entities (agricultural enterprises, peasant farms, private household plots and agricultural holdings), the loss of communication between villagers and agricultural enterprises, the villagers models of social adaptation and labor behavior. These processes served as a methodological support for the analysis and empirical evidence of how consciously villagers have been changing social and labor practices under the pressure of institutional transformations and agricultural modernization. Based on the choice of rational behavioral models in the labor market, they transformed the social structure of the village under the pressure of the market economy values, new rules, norms and institutional requirements. Modern processes in the agro-industrial field in the context of the property transformation contributed to the formation of a new agrarian structure, constructed by new subjects. The new and old production subjects interact in a multi-structured economy. They are important “players” in the institutional field of the agricultural sector, thus influencing the social and structural processes in the labor market. This determined a new configuration of the social rural groups employed in the formal and informal sectors.
Physical simulation of intra-arterial circulation using an experimental bench
Authors: Germanova O. A. , Germanov V. A. , Shchukin Yu. V. , Germanov A. V. , Burmistrov A. E. , Yusupov R. Y. , Prokhorenko I. O.
Published: April 2021

The article describes the device and possibilities of application of the original device developed by us for simulation of intra-arterial circulation. The principles of operation of the device, a wide range of experimental and clinical studies in which it can be applied are outlined. The use of this useful model is illustrated by clinical examples.
Extrasystoles: adverse effects of the first postextrasystolic contraction
Authors: Germanova O. A. , Germanov V. A. , Shchukin Yu. V. , Germanov A. V. , Piskunov M. V.
Published: April 2021

Aim. To determine the changes of parameters of heart biomechanics and kinetics of arteries, to reveal the adverse events of first post-extrasystolic contraction.

Materials and methods. In our investigation we included 286 patients. We excluded all the main traditional risk factors of the atherosclerosis. All the patients were branched into two main groups in accordance to the quantity of extrasystoles per 24 hours: I group – less than 3000, II group – more than 3000 extrasystoles per 24 hours. We took the data about complaints, anamnesis, made laboratory and instrumental investigations to reveal the character and severity of atherosclerotic process.

Results. We determined that the atherosclerotic process was more advanced and more often in the group II. Also the atherosclerosis was more severe in patients with extrasystoles in the phase of cardiocycle before opening of the mitral valve and before the transmitral blood flow peak. The parameters (acceleration, speed, power, work) that were calculated by apexcardiography and sphygmography increased with the further tendency: if earlier extrasystole appears in cardiocycle, than more changes were observed.

Conclusion. The first post-extrasystolic contraction causes the increase of all parameters of heart biomechanics and kinetics of vessels and can be an additional factor of progressing of atherosclerosis.
Analysis of the possibility of dental tissue reproduction in vitro with subsequent in vivo replantation
Authors: Litvinov S. D. , Rakhimov R. I.
Published: April 2021

The article gives the prognosis of obtaining (forming, growing) a dental rudiment on the material “LitAr” for the purpose of implantation into the alveolar process of the jaw after the loss of a permanent tooth regardless of the age of the patient. The procedure should consist of two steps: 1) autonomous cultivation (formation) of a tooth rudiment; and 2) implantation of the resulting rudiment in place of the lost permanent tooth.
On fixation of tissue-engineered structures on the surface of hyaline cartilage
Authors: Zherebtsova Y. V. , Trushnikov V. V. , Nashchekina Y. A. , Nikonov P. O. , Vcherashniy D. B. , Novoseltsev S. V. , Kruglov V. N.
Published: April 2021

The work is devoted to the experimental substantiation of the techniques for fixing tissue-engineered structures on the surface of the hyaline cartilage in the experiment.
Prevalence of Tobacco Smoking in Patients with Schizophrenia and Bipolar Disorder in a Portuguese Hospital
Authors: Lopes Joana , Silva Inês
Published: April 2021

N/a.
Errata ao artigo “Ensaios Clínicos em Portugal: Como Podemos Melhorar?”, Publicado em Acta Med Port 2021 Feb;34(2):80-83.
Authors: De Sousa Carla
Published: April 2021

No rodapé da página 80, afiliação dos autores, onde se lê:“3. Departamento de Psicologia Clínica e da Saúde. Hospital da Luz. Lisboa. Portugal.”Deverá ler-se:“3. Centro de Investigação da Learning Health. Hospital da Luz Learning Health. Lisboa. Portugal.”Artigo publicado com erros: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15155
The association of the IL-1ß-31 polymorphism and the development of neuroinfections
Authors: Biesiada Grażyna , Czepiel Jacek , Piątek Anna , Birczyńska Malwina , Żurańska Justyna , Wołkow Paweł , Perucki William , Jędrychowski Michał , Garlicki Aleskander
Published: April 2021

Introduction. Inflammation of the meninges can have various clinical courses, from mild, self-limiting in some viral neuroinfections to severe, sometimes ending in death. The pro-inflammatory cascade and defects in the inhibitors of the inflammatory response play an important prognostic role. Single nucleotide polymorphisms (SNPs) of the genes encoding cytokines, influence the severity of the inflammatory response.Aim. The aim of this study was to evaluate the effect of selected polymorphisms of proinflammatory cytokines IL-1ß, TNF-? and IL-8 on the development of neuroinfections.Material and Methods. We evaluated the laboratory results of 30 patients treated for bacterial and viral meningitis and compared those to 30 healthy volunteers. The following 4 variants were analyzed for occurrence of genetic polymorphism in patients with meningitis versus the control group: IL-1ß 3953, IL-1ß -31, TNF-? -308, and IL-8 781. Then, we assessed the association between these genetic polymorphisms and the inflammatory response during the course of meningitis.Results and Conclusions. We observed that polymorphism of the IL-1ß-31 significantly differs between patients and healthy subjects, the IL-1ß -31AA polymorphism existed only in healthy individuals (p < 0.001). The WBC count was dependent on the TNF-? -308 polymorphism with a statistically significant difference (p = 0.021) occurring among persons with variants AA and AG. In conclusion the study showed that the presence of the AA genotype of IL-1ß-31polymorphism may have a protective effect on the development of meningitis. This polymorphism was not observed in any patient with meningitis.
Assessment of nutritional status and feeding methods in patients with inflammatory bowel disease
Authors: Swora-Cwynar Ewelina , Karczewski Jacek , Musiał Anna , Grzymisławski Marian , Marcinkowska Emilia , Dobrowolska Agnieszka , Mańkowska-Wierzbicka Dorota
Published: April 2021

Aim. The aim of this study was to evaluate diet of patients with IBD, their nutritional status and potential differences as compared to diet of healthy persons.Material and methods. The examination included the patients of Internal, Metabolic Diseases and Dietetics Ward and Gastroenterology, Internal Diseases and Human Nutrition Ward of Heliodor Święcicki Clinic in the Poznan University of Medical Sciences in Poznan. The criterion allowing participation into the study involved a diagnosed ulcerative or Crohn’s disease, basing on histopathology and radiological examination. The study was conducted on 50 patients, 25 women and 25 men. The control of group included 50 persons, 30 women and 20 men, potentially healthy and occupationally active. In the study the authors' own questionnaire was used, which contained questions related to diet and evaluating conditions of nutrition, based on the results of anthropometric measurements and selected biochemical parameters.Results. The study documented that IBD affected diet, which proved to be distinct from that of potentially healthy person. Course of the disease reduced some laboratory parameters in serum: decreased levels of total protein were detected in 40% patients, reduced levels of albumin in 28% patients and of haemoglobin in 72% patients with IBD. Most of patients introduced some modifications and dietary restrictions to reduce the symptoms and prolong remission. Presentation of such attitudes, indicates a need for an effective multidirectional education, which should affect a conscious decision making about the diet. The Body Mass Index and evaluation of nutrition demonstrated that IBD predisposed development of malnutrition: as compared to the control group, 28% of the patients manifested underweight.
Foot arch condition in comparison with the muscular balance of lower limbs in children at school age of 6–14 years
Authors: Skowron Natalia , Malak Roksana , Mojs Ewa , Samborski Włodzimierz
Published: April 2021

Introduction. Foot arch condition plays an important role in correct setting of lower limbs joints, proper muscles tone and well-being [1]. More and more frequently foot arch deviations affect population of school age children [2, 3]. It is based on anatomic knowledge that abnormal foot arch is strongly connected with the disturbed muscle tone of lower limb. The aim of the presented study is to evaluate the relation between the foot arch condition and muscular balance of the lower limbs.Material and methods. Children were assessed using the Clarke’s angle and indicatory muscles length tests including: quadratus lumborum muscle, hamstring muscle, thigh adductors, piriformis muscle.Results. Abnormal foot arch was showed by 70% of subject children. The greatest number of muscles length abnormality was observed in quadratus lumborum muscles. There was a statistically significant correlation between right hamstring muscle contraction and abnormal foot arch (p = 0.011). Conclusions. Foot arch alternations increasingly more often appear in the greater number of school–age children. The assessment and therapy of abnormal foot arch should include the examination of muscular balance of the lower limbs.
Homocysteine – relation to hypertension, age and smoking in patients with newly diagnosed essential hypertension
Authors: Korzeniowska Katarzyna , Cieślewicz Artur , Chmara Ewa , Jabłecka Anna
Published: April 2021

Introduction. An elevated circulating concentration of homocysteine is associated with an increased risk of coronary, cerebral, and peripheral vascular disease. The purpose of this study was to determine the concentrations of homocysteine in the patients with newly diagnosed essential hypertension and healthy subjects and to analyze the correlation between homocysteine level and the other parameters (age, blood pressure, smoking).Material and methods. The study group consisted of 18 patients with essential hypertension, 4 women and 14 men (mean age 43 ± 16 years) and 15 healthy volunteers, 8 women and 7 men (mean age 47 ± 10 years). Serum homocysteine was analyzed by FPIA method (Fluorescence Polarization Immunoassay).Results. The patients with essential hypertension had significantly higher homocysteine concentration compared to control group. No correlation was observed between homocysteine levels and age, diastolic, systolic blood pressure in subjects with essential hypertension. In healthy volunteers, only a correlation between age and homocysteine concentration was found.
TAZ oncogene as a prognostic factor in breast cancer
Authors: Glapa Aleksandra , Nijak Aleksandra
Published: April 2021

Breast cancer is the most frequently diagnosed cancer in females and one of the main causes of cancer related deaths. Breast cancer in the metastatic stage is related with poor prognosis. Metastasis is the process whereby cancer cells travel to and colonize distant sites through the lymphatic system or bloodstream, which usually indicates a poor prognosis. The metastatic cascade involves several molecular and cellular interactions and different signaling pathaways. Recently the Hippo signaling has emerged as an important regulatory pathway in cancer. The Hippo target protein TAZ has been reported as a novel oncogene that may have important role in the development of breast cancer. Its overexpression promotes cancer stem cell formation and epithelial–mesenchymal transition in many human cancers. In breast TAZ seems to play a critical developmental role and in breast cancer is one of the factors involved in therapeutic resistance and clinical relapse. Herein, we review the biological functions of TAZ and summarize the current knowledge and opportunities for therapeutic intervention in this field.
Evaluation of radiological parameters after distal radius fracture in elderly people
Authors: Zaręba Adam
Published: April 2021

Introduction. Distal radius fractures are one of the most frequent problems in every day practice and almost 17% of all fractures in adults. We have to very often face effects of low-energy trauma in elderly people. Osteoporotic bone and composed morphology of fracture forces surgeon to consider operation among the best options of treatment.Aim. This is an attempt to compare radiological results achieved by closed reduction and cast immobilization versus open reduction and internal fixation with „Aptus®” (Medartis, Basel Switzerland) volar plate, as well as dynamics of redisplacement during immobilization based on radiological parameters of distal radius.Material and methods. There were 101 patients in examined group, aged 60 to 91. Results. Internal fixation lead to smaller secondary displacement comparing to cast immobilization, but significancy varies depending on fracture morphology. Redisplacement during cast immobilization was comparable during first seven days and following weeks previous to removal of splint
Acute kidney injury after cardiac surgical operations specially including coronary artery bypass graft operations
Authors: Lipski Adam , Szymoniak-Lipska Marta , Greberski Krzysztof
Published: April 2021

Introduction. Acute kidney injury as abrupt loss of kidney function leads to accumulation nitric and non-nitric metabolites, toxins. It coexists with deep disorder of fluid balance. Most of cardiac surgical operations are performed using extracorporeal circulation (ECC). To the main risk factors of the postoperative dysfunction of kidneys belong: age above 70, congestive heart failure, previous CABG, preoperative creatinine concentration 124–177 µmol/L, diabetes type I, glucose concentration > 16,6 mmol/L, EEC longer than 3 hours and decreased cardiac output (CO).Material and methods. The serum creatinine is not enough sensitive marker to diagnose early period of acute kidney injury because the serum creatinine increase occur later than true GFR changes and it needs time to accumulate. It depends on factors like: age, sex, weight, hydration status and what patient eat. NGAL (neutrophil-gelatinase associated lipocalin), cystatin C, KIM-1, IL-18, L-FABP are new markers of acute kidney injury which better than the serum creatinine concentration correspond with kidney injury. The risk factors of the acute kidney injury (AKI) are kidney hypoperfusion, microembolisation by bubbles or material particles and significant activation of humoral factors.Results. One of the methods reducing mortality CSA-AKI (cardiac surgery associated kidney injury) is renal replacement therapy (RRT), which should be used in early period of acute kidney disease before severe symptoms and complications develop.Conclusions. There is necessity to find early, easy and cheap markers of acute kidney injury which help decide if use renal replacement therapy. It increases the effectiveness of treatment and improves prognosis in this group of patients.
Characteristic of no-synthase of peripheral blood lymphocytes of patients with rheumatic pathology
Authors: Efremova Ulyana , Lychkovska Nataliya , Fafula Roman , Vorobets Zinoviy
Published: April 2021

It is known that NO is a ubiquitous mediator which acts as a universal modulator of various functions in organism and is produced by three isoforms of NO synthase. Nowadays the role of NO in the development of autoimmune diseases is actively studied. However, it remains unclear the biochemical and biophysical mechanisms of disturbances of NOS activity in blood lymphocytes at autoimmune process. The aim of present work is to study the kinetic properties of NO-synthase of peripheral blood lymphocytes of patients with rheumatic pathology. The study was carried out on peripheral blood lymphocytes isolated from patients with rheumatoid arthritis and ankylosing spondylitis. NOS activity was determined on the saponin-permeabilized blood lymphocytes. The difference between the values of NADPH oxidation with L-Arg and with inhibitor L-NAME reflects the value of the NADPH oxidation, ie total NOS activity. The kinetic properties of NO-synthase in peripheral blood lymphocytes of patients with rheumatic pathology were studied. It was found that the development of rheumatic pathology is associated with an imbalance in the NO synthesis and changes of kinetic parameters of NOS. It was shown that reduction in eNOS activity is accompanied by a sharp increase in activity of its inducible form. It was established that inhibition of eNOS occurs by noncompetitive type. NO production in lymphocytes of patients with rheumatic diseases is mainly realized by iNOS, whereas under normal physiological conditions endothelial form of the enzyme is being involved.
Legal aspects of a healthy diet for children. Comments on the grounds of the directive on foodstuffs in schools
Authors: Urbaniak Monika
Published: April 2021

The aim of this article is to analyze legal solutions for the availability of foodstuffs in schools, binding from Sep 1, 2015, targeted to introduce into school shops and canteens so-called healthy food. The Directive issued by the Minister of Health on Aug 26, 2015 on groups of foodstuffs intended to be sold to children and young people in education system units and requirements for foodstuffs used within collective feeding of children and young people in those units eliminated from school shops provide a list of food which is considered unhealthy. The adopted solutions are an introduction to the legal statutory fight against obesity in children and young people and enhance the protection of the health of children at pre-school and school age by limiting access within kindergartens, schools and tutelary-educational institutions to foodstuffs containing significant quantities of ingredients not recommended for their development.
Long QT in stunned myocardium: unrecognised cause of acquired long QT syndrome
Authors: Sacha Jerzy
Published: April 2021

Long QT syndrome (LQTS) is a heart disorder characterized by a prolongation of the QT interval on ECG and a predisposition to ventricular tachyarrhythmias, which may lead to syncope, cardiac arrest or sudden cardiac death. This condition may be inherited or induced by external factors such as drugs, electrolyte imbalances and some acquired cardiac diseases. The review addresses LQTS caused by acute cardiac illnesses which are associated with a large amount of stunned myocardium, i.e. the reperfused myocardial infarction and the group of stress-related cardiomyopathies. In these cases, specific ECG evolutionary changes may be observed, i.e. dynamic deep T-wave inversion and QT interval prolongation which predispose to fatal polymorphic ventricular tachyarrhythmia, i.e. torsade de pointes. However, lethal arrhythmias are relatively rare in these instances and probably concern patients with an underlying predisposition to LQTS. The pathological mechanisms of both repolarization abnormalities and ventricular arrhythmias as well as the practical approach how to interpret electrocardiographic changes and identify high risk patients are discussed in this review.
Clinical outcomes of conjugated linoleic acid supplementation in the overweight and the obese: a study protocol
Authors: Łochocka Klaudia , Glapa Aleksandra , Nowak Jan Krzysztof , Duś-Żuchowska Monika , Grabańska Katarzyna , Bogdański Paweł , Fidler Ewa , Mądry Edyta , Walkowiak Jarosław
Published: April 2021

This is the protocol of a study aiming to assess the impact of conjugated linoleic acid (CLA) on body mass and composition, carbohydrate and fat digestion and absorption, total energy expenditure, lipid profile, polyunsaturated fatty acids levels, markers of endothelial dysfunction and mineral status in humans. Seventy-four adult volunteers (BMI ? 25 kg/m2) will be randomized to receive 3.0 g of 80% CLA (50:50 cis-9, trans-11 and trans-10, cis-12 isomers) or 3.0 g of linoleic acid daily for 3 months. A range of parameters will be measured at baseline and after the intervention.
Augmenting Paraphrase Generation with Syntax Information using Graph Convolutional Networks
Authors: Chi Xiaoqiang , Xiang Yang
Published: April 2021

Paraphrase generation is an important yet challenging task in NLP. Neural network-based approaches have achieved remarkable success in sequence-to-sequence(seq2seq) learning. Previous paraphrase generation work generally ignores syntactic information regardless of its availability, with the assumption that neural nets could learn such linguistic knowledge implicitly. In this work we make an endeavor to probe into the efficacy of explicit syntactic information for the task of paraphrase generation. Syntactic information can appear in the form of dependency trees which could be easily acquired from off-the-shelf syntactic parsers. Such tree structures could be conveniently encoded via graph convolutional networks(GCNs) to obtain more meaningful sentence representations, which could improve generated paraphrases. Through extensive experiments on four paraphrase datasets with different sizes and genres, we demonstrate the utility of syntactic information in neural paraphrase generation under the framework of seq2seq modeling. Specifically, our GCN-enhanced models consistently outperform their syntax-agnostic counterparts in multiple evaluation metrics.
Game-Based Learning and Assessment for History Education
Authors: Lee Woo Hyun , Park Sang Yong , Lee Won Hyung
Published: April 2021

Regardless of country and age, the importance of history education is always being emphasized. Although the importance of history education is being emphasized in Korea, there are many difficulties in getting students to understand history properly through school classes alone, and it is also difficult to attract students to participate in classes. The effectiveness of education using games has been proven 20 years ago, and the demand for game-based education is gradually increasing in the current education world, which is becoming more open. In this paper, based on the effects proven through research on the existing game-based education, the improvement of historical thinking ability, experiential history learning, and the problems of game-based education introduced in the ESN report and the discomfort of teachers who participated in the education were improved. A plan was suggested to select and use games suitable for basic education. In this thesis, we selected a history game with a clear historical and periodic background and without distortion of history, and experimented with teaching using games focusing on historical thinking and empirical history learning. The learning achievement of textbook-based education was compared.
Assessing Institutional Support to Online Education at Tertiary Level in Bangladesh Coping with Covid-19 Pandemic: An Empirical Study
Authors: Nur Ullah Mohammad , Biswas Bikram , Mamun Miah Md.
Published: April 2021

Institutional support and quality education are linked in a significant way. During Covid-19, institutional support is critical to closing the huge academic gap that has emerged as physical academic practices have been moved to a virtual education system using technology. This research aims to assess institutional support for online education in Bangladesh during the Covid-19 pandemic. This analysis is focused on the three main elements of the Adapted Model of Institutional Support (AMIS) of Bond et al, 2007, and the Institutional Support Model (ISM) of Valverde and Rodriguez, 2002, namely Financial Support (FS), Technical Support (TS), and Mentoring Support (MS). According to the findings, a few universities in Bangladesh have provided average support for continuing online education, while others have just started taking online classes. Several problems have been discovered, such as the lack of dedicated software for conducting online academic activities, lack of training and grooming, lack of mentoring, poor internet access, lack of smartphones, high internet package rates, and so on. This study concludes with some policy recommendations for a smooth online education system in Bangladesh.