bluuebunny/crossref_metadata_2025 huggingface dataset:
Nível de atividade física e prevalência de quedas em idosos residentes em um município do sudoeste do Paraná
Authors: Lima Patrine Kieling de , Kasmarek Jéssica Rigon , Munaro Chiara , Bortoloti Durcelina Schiavoni
Published: September 2019

OBJETIVO: Verificar a associação entre nível de atividade física e prevalência de quedas em idosos de Francisco Beltrão/PR.MÉTODOS: Estudo conduzido com 305 idosos, com idade média de 69,09±7,05 anos, residentes em Francisco Beltrão. O instrumento utilizado para analisar o nível da atividade física habitual (NAFH) foi o questionário IPAQ, em sua versão curta, no qual foram acrescentadas perguntas referentes a quedas nos últimos 12 meses. Foi empregada a estatística descritiva para caracterização da amostra e o teste de qui-quadrado para verificar a associação entre o NAFH e as quedas. Utilizou-se o programa estatístico SPSS versão 20.0, e o nível de significância adotado foi de P<0,05.RESULTADOS: Identificou-se que do total de 305 idosos, 66,9% foram classificados como mais ativos e 33,1% como menos ativos para o NAFH. Para a pergunta referente a quedas aos últimos 12 meses a prevalência de quedas encontrada foi de 27,2%. Desses 305 idosos avaliados, 27,2% (n=83) relataram ter sofrido ao menos uma queda no último ano, os quais 56 foram classificados como mais ativos, e 27 foram classificados como menos ativos. Não foram identificadas associações significantes entre NAFH e quedas nos idosos deste estudo (P>0,05).CONCLUSÕES: Não foi verificada associação significativa entre as quedas relatadas pelos idosos nos últimos 12 meses e o NAFH.
Análise temporal da cobertura do solo no território dos cocais usando sensoriamento remoto
Authors: Caselli Francisco De Tarso Ribeiro , Espindola Giovana Mira de , Lopes João Batista
Published: September 2019

Os Sistemas de Informação Geográfica (SIG) constituem importante ferramenta de acompanhamento do processo de uso e cobertura do solo. Neste sentido, com o presente estudo buscou-se analisar o uso e cobertura do solo do Território dos Cocais no Piauí e seus possíveis impactos na produção de coco babaçu. A metodologia consistiu na utilização de imagens de satélite LandSat 5 e 8 TM e construção de carta de uso e ocupação do solo para quatro munícipios do território, entre os anos de 1990 e 2015. Também, foram utilizados dados estatísticos do IBGE sobre a produção de coco babaçu. Os resultados apontam para o aumento da área do solo exposto entre 1990 e 2015, de 2% para 8% do território estudado, enquanto a mata ciliar foi reduzida a 50% e a produção de amêndoa de coco babaçu de 72%, quando analisada a série dos anos compreendidos entre 1975 e 2015.
Os Institutos Federais de Educação e o Sistema Nacional de Inovação: a infraestrutura acadêmica de pesquisa como contribuição ao processo de inovação nacional
Authors: De melo José Nilton , Da Silva Gabriel Francisco , De Santana José Ricardo
Published: September 2019

Este trabalho tem como objetivo realizar um levantamento exploratório sobre as características físicas e humanas das infraestruturas de pesquisa dos Institutos Federais de Educação, Ciência e Tecnologia (IFs), tendo em vista que a recente transformação dos Centros Federais de Educação Tecnológica – CEFETs e das Escolas Agrotécnicas Federais em IFs trouxe alguns desafios, dentre eles a necessidade de adequar a infraestrutura de pesquisa herdada a fim de cumprir a nova missão institucional. Desta forma, quais as principais características das infraestruturas de pesquisa dos IFs e qual o perfil dos recursos humanos existente nelas? O trabalho busca responder essas questões apresentando e interpretando os dados primários oriundos do mapeamento inédito realizado pelo MCTIC/CNPq/IPEA, os quais foram disponibilizados pela Diretoria de Estudos e Políticas Setoriais de Inovação e Infraestrutura (DISET-IPEA). Do total de 1760 infraestruturas de pesquisa que participaram do levantamento geral, 61 pertencem aos IFs, sendo esta a base de dados utilizada. O presente estudo mostrou que os IFs possuem uma forte associação com as áreas de ciências exatas, da terra e engenharias, demonstrando um grande potencial de aproximação das atividades de ensino e pesquisa com as demandas tecnológicas do mercado, sobretudo da indústria, o que poderá contribuir para a construção de um Sistema Nacional de Inovação mais moderno, dinâmico e competitivo. Contudo, ainda necessita de incentivos para tornar seus espaços físicos maiores, atrair mais estudantes de graduação, pesquisadores com vínculos de bolsistas e celetistas e também melhorar a gestão financeira de seus laboratórios.
Potencial dos sistemas de armazenamento flywheel para a qualidade da produção de energia: aplicações
Authors: Mendes do Carmo Carlos Eduardo , Tatizawa Hédio
Published: September 2019

Este estudo é uma revisão sobre os sistemas de armazenamento de energia tipo Flywheel abordando sua história, desenvolvimento, suas características e aplicações como método de estocagem de energia e auxílio para a minimização de problemas decorrentes de anormalidades no fornecimento de energia. Os sistemas de armazenamento de energia tipo Flywheel apresentam algumas vantagens em relação as alternativas disponíveis tais como: alto ciclo de vida, alta densidade de potência e baixo impacto ambiental. Este artigo inclui características construtivas dos sistemas Flywheel e suas aplicações conjugadas as soluções de fornecimento de energia renovável.
Taste Masking of Enalapril Maleate by the Precipitation Method
Authors: Georgieva Yana Zh. , Pilicheva Bissera A. , Kokova Vesela Yu. , Apostolova Elisaveta G. , Kassarova Margarita I.
Published: September 2019

Background: Taste masking of bitter or unpleasant drugs is an important prerequisite to improve patient compliance, especially for children and elderly patients. We aimed at obtaining taste-masked microparticles intended for incorporation into orodispersible tablets (ODTs). We selected the precipitation method using enalapril maleate (ENA) as a model bitter-tasting drug and Eudragit EPO® as a pH sensitive polymer.

Aim: The aim of this study was to obtain microparticles with enalapril maleate by the precipitation method in order to mask the bitter taste of the drug.

Materials and methods: Nine models of enalapril maleate – Eudragit EPO® microparticles were prepared by the precipitation method at varied drug-polymer ratios. The models were characterized in terms of size, shape, production yield, drug content, encapsulation efficiency and moisture content. Fourier-transformed infrared spectroscopy, powder X-ray diffraction and differential scanning calorimetry were used to analyze possible interactions in the complex. In vitro drug release in simulated salivary fluid and in vivo taste evaluation in rats were realized to prove taste masking.

Results: The particle size distribution varied from 266.9 µm to 410.9 µm. The shape of the resulting particles was irregular. The production yield varied from 23.6% to 78.2%. The drug content ranged between 2.3% to 4.8%, encapsulation efficiency increased from 1.6% to 9.0%. In vitro drug release data indicated significant taste masking.

Conclusion: Some of the obtained microparticles by the precipitation method showed satisfactory taste masking efficiency, which proved the taste masking feasibility of this method.
First Report of DHA-1 Producing Enterobacter cloacae Complex Isolate in Bulgaria
Authors: Dimitrova Dobromira I. , Markovska Rumyana D. , Stoeva Temenuga J. , Stankova Petya B. , Georgieva Lyudmila B. , Mihova Kalina I. , Kaneva Radka P. , Mitov Ivan G.
Published: September 2019

The aim of the present study was to reveal the characteristics of an Enterobacter cloacae complex isolate producing DHA-1 AmpC enzyme recovered from a patient hospitalized in St Marina Hospital, Varna.

Materials and methods: Susceptibility testing, conjugation experiments, isoelectric focusing, PCR and sequencing were carrying out.

Results: Of 176 Enterobacter spp. isolates only one isolate was positive for blaDHA. The sequencing revealed the presence of blaDHA-1 and blaCTX-M-3. The antimicrobial susceptibility testing showed higher resistance rates to almost all beta-lactams (ceftazidime, cefotaxime, cefepime, amoxicillinclavulanic acid, piperacillin/tazobactam), tobramycin, gentamycin, trimethoprim/sulphomethoxazole and quinolones (ciprofloxacin and levofloxacin). The isolate was susceptible to imipenem, meropenem and amikacin. The isoelectric focusing showed a band at pI 5.4 without ceftazidime and cefotaxime activity; a band at pI 7.8 with cefoxitin activity and another - with pI 8.4 with cefotaxime activity. Conjugation experiments were successful only for blaCTX-M-3 carrying determinants. 

Conclusions: To the best of our knowledge this is the first report of DHA-1 producing isolate in Bulgaria. The emergence of DHA-1 producing E. cloacae complex demonstrates the possibility for further dissemination of the gene encoding this enzyme. Infectious control measures are needed for the prevention of this phenomenon.
Myelomeningocele with Associated Anomalies – Case Report and Literature Review
Authors: Kitov Borislav , Kehayov Ivo
Published: September 2019

Myelomeningocele is a common defect of the development of the neural tube. It is a complex congenital malformation of the central nervous system (CNS) that can be associated with other concurrent anomalies. We report on a case of lumbar myelomeningocele with concomitant CNS malformations we followed up over a period of 15 years. A concise literature review has also been performed. The current report illustrates that the myelomeningocele is a complex anomaly that is commonly associated with a variety of other CNS malformations such as hydrocephalus and Chiari malformation. It may follow chronic progressive course with exacerbation of clinical symptoms in the long term. Patients that have undergone surgical correction of this spinal defect should be closely monitored over a long period of time because of the possibility of clinical deterioration of the concomitant anomalies such as hydrocephalus, Chiari malformation and siryngomyelia.
Influence of silver-ion-containing pharmacotherapeutic system for repair of anterior abdominal wall on connective tissue formation in experiment
Authors: Mishina Ekaterina S. , Zatolokina Marija A. , Gureeva Anastasia V. , Gureev Vladimir V. , Elagina Karina A. , Zatolokina Eugenia S.
Published: September 2019

Introduction: In modern medicine new pharmacotherapeutic systems significantly reducing the risk of complications are being actively searched for. The study undertaken was aimed at studying one of such systems consisting of a prosthesis coated with silver ions.

Materials and methods: The material for the study was standard endoprostheses produced by Lintex LLC (St.-Petersburg) for plastic repair of the anterior abdominal wall: Esfil and Uniflex, as well as Plasmofilter produced by Plasmofilter JSC (St.-Petersburg) and a pharmacotherapeutic system containing silver ions (FCS) applied to the experimental samples of endoprostheses – Esfil Ag and Unifleks Ag (patent RU 2473369C1), which were implanted into male Wistar rats. The results were evaluated using morphological, morphometric, immunohistochemical, ionometric, microbiological and statistical methods.

Results and discussion: As a result, it was found that the use of the FCS leads to a more rapid change in inflammation phases. The formation of a mature connective tissue capsule with a thickness of 4.5±0.01 mm was observed by Day 30. The study of the cellular component of the periprosthetic tissue revealed the prevalence of resident cells. The proliferative activity of fibroblastic cells when using FCS over 14 days was statistically significantly (p≤0.05) 3.5-time higher. Microbiological studies confirmed the antibacterial properties of FCS in vivo and in vitro.

Conclusion: The use of FCS contributes to the acceleration of reparative processes, earlier resolution of inflammation and stimulation of collagenesis both under sterile conditions and under microbial conditions.
Neuroprotective effects of taurine and 3-hydroxypyridine derivatives in the intracerebral hemorrhage model in rats
Authors: Nesterova Natalia I. , Shcheblykina Olesya V. , Kolesnichenko Pavel D. , Nesterov Arkady V. , Shcheblykin Dmitry V. , Popova Irina A. , Yakovlev Dmitry V.
Published: September 2019

Introduction: At present, the problem of pharmacological correction of free radical processess emerges full-blown. The aim of the study is an experimental study of the neuroprotective effect of taurine and 3-hydroxypyridine derivatives.

Materials and methods: The study was performed in Wistar rats. The neuroprotective effect of the substances was studied in the intracerebral hemorrhage model.

Results and discussion: The administration of the studied substances had a positive effect on the survival of the animals within the first day (50% of rats died in the control group, 30% – in the Mexidol- and Ethoxidol-treated groups, and 20% – in LKhT 3-17-treated group). Within the first day after the surgery, all rats with stroke had severe neurological disorders. However, by the 3rd day, the Ethoxidol- and LKhT 3-17-treated rats had a lower neurological deficit. By Day 14, all groups of animals treated with the test substances had a lower severity of post-stroke disorders than those in the control group, which was evident as a 1.5-time lower McGraw Stroke Index score. LKhT 3-17 substance showed the most pronounced neuroprotective effect.

Conclusions: The studied derivatives of taurine and 3-hydroxypyridine have a neuroprotective effect, which is manifested in the lower severity of neurological disorders,a more rapid reduction in the signs of neurodegeneration and accelerated hemorrhage processes.
Maximum tolerant dose and analgesic activity of PT1 peptide
Authors: Palikova Yuliya A. , Palikov Viktor A. , Dyachenko Igor A.
Published: September 2019

Introduction: The article presents the results of the study of the maximum tolerant dose (MTD) and the analgesic activity of peptide PT1 isolated from Alopecosa marikovskyi spider venom. PT1 is the first compound of polypeptide nature, capable of exerting a selective modulating effect on purinergic P2X3 receptors.

Materials and methods: The study was conducted on 174 ICR mice. The analgesic activity of the peptide was evaluated in a thermal hypersensitivity test triggered by CFA and in a model of chemical irritation.

Results and discussion: The determined MTD for the peptide PT1 when administered intravenously provides evidence to attribute it to low-toxic compounds. The maximum analgesic activity of PT1 using the biomodel of hypersensitivity induced by CFA when tested 15 minutes after the administration was recorded at doses of 0.1 and 0.5 mg/kg. In the visceral pain test, the maximum analgesic activity 15 minutes after the administration of the chemical stimulus was observed at a dose of 0.01 mg/kg.

Conclusions: According to the results of testing peptide PT1, it is shown that it belongs to low-toxic compounds, has a pronounced analgesic activity in a wide range of doses of 0.0001–10 mg/kg.
Search for new pharmacological targets for increasing the efficiency of correction of cardiovascular diseases
Authors: Korokina Liliya V. , Golubev Ivan V. , Pokopejko Olga N. , Zagrebelnaya Anastasia V. , Demchenko Sergey A.
Published: September 2019

Introduction: Cardiovascular disease (CVD) is the leading cause of death worldwide: no other reason causes as many deaths a year as CVD. An estimated 17.9 million people died of CVD in 2016, accounting for 31% of all deaths in the world. People with CVD or at high risk for these diseases (due to one or more risk factors, such as high blood pressure, diabetes, hyperlipidemia, or an already developed disease) need early detection and assistance through counseling and, if necessary, taking medication.

Ways to find new targets for the correction of endothelium-associated pathology: The basis of the modern therapy for arterial hypertension and other cardiovascular diseases is the postulate of the need to correct endothelial dysfunction as an indication of the adequacy of antihypertensive and other types of treatment. Lowering blood pressure (BP) without normalizing endothelial function cannot be considered a successfully resolved clinical task. Currently, there are no drugs for specific pharmacological correction of endothelial dysfunction in cardiovascular diseases, and the search for new targets for pharmacological correction of endothelial dysfunction is one of the main tasks of pharmacology.
Mortality of primates due to roads and power lines in two forest patches in Bangladesh
Authors: Al-Razi Hassan , Maria Marjan , Bin Muzaffar Sabir
Published: September 2019

Primates are in imminent risk of extinction due to different types of anthropogenic activities. Mortality due to road accidents and electrocution from power lines are among the major direct anthropogenic threats to the survival of primates. We collected primate mortality data from 2015 to 2017 at Lawachara National Park and Satchari National Park in northeastern Bangladesh. We recorded 27 fatalities in five species of primates caused by road accidents (n = 15) and electrocution (n = 12). Most mortality records were forTrachypithecus phayrei(Blyth, 1847) (n = 8) while the lowest recorded mortality was forMacaca mulatta(Zimmermann, 1780) (n = 3). Ninety percent of primates in Bangladesh are threatened and populations are gradually declining. Our results suggest that roads and power supply lines are major sources of primate mortality that should be managed in these two forests. We strongly suggest avoiding construction of roads and power supply lines inside forests. Furthermore, control of the speed limit of vehicles inside the forests, use of insulated power lines, maintenance of natural canopy bridges and preparation of artificial canopy bridges are strongly recommended.
Mining possible associations of faecal A. muciniphila colonisation patterns with host adiposity and cardiometabolic markers in an adult population
Authors: Mitsou E.K. , Detopoulou M. , Kakali A. , Fragopoulou E. , Nomikos T. , Antonopoulou S. , Panagiotakos D.B. , Kyriacou A.
Published: September 2019

We aimed to evaluate colonisation patterns of Akkermansia muciniphila in a Greek adult population and to investigate model-adjusted associations of A. muciniphila with host adiposity and cardiometabolic markers. Participants (n=125) underwent anthropometric, dietary, physical activity and lifestyle evaluation. Blood sampling for determination of blood lipid indices, glucose metabolism, adiponectin, lipoprotein-associated phospholipase A2 (Lp-PLA2), inflammation and oxidative stress parameters was also performed. Stool A. muciniphila presence and levels were determined by quantitative PCR and subjects were grouped based on bimodal distribution of levels (Low vs High). A. muciniphila was detected in 88.6% of participants. Overweight/obese (OW/OB) subjects were more prone in low bimodal levels of A. muciniphila compared to normal-weight (NW) individuals (58.75 vs 27.59%, P=0.004), with a 4-time greater likelihood after multi-adjusted logistic regression analysis (P=0.016). Levels of A. muciniphila were negatively associated with total cholesterol/high-density lipoprotein cholesterol (TC/HDL-C) ratio (log10:-0.009±0.004, P=0.033), whereas detection of this bacterium was negatively associated with both TC/HDL-C ratio (log10: -0.049±0.023, P=0.036) and low-density lipoprotein cholesterol/HDL-C ratio (-0.407±0.176, P=0.023). Furthermore, low bimodal levels of A. muciniphila were positively associated with fasting blood glucose (log10: 0.018±0.009, P=0.037). In terms of inflammation markers, levels of A. muciniphila were positively associated with soluble cluster of differentiation-14 (sCD14) (log10: 0.012±0.004, P=0.003) and faecal detection of this bacterium had a positive association with anti-inflammatory interleukin 10 levels (log10: 0.325±0.131, P=0.015). In addition, A. muciniphila levels were positively associated with total adiponectin (log10: 0.046±0.015, P=0.002), whereas low bimodal levels of A. muciniphila had an inverse relationship with this blood marker (log10: -0.131±0.053, P=0.016). In conclusion, we confirmed the previously reported association of A. muciniphila with metabolic health for the first time in a Greek urban population; furthermore, we shed some light to novel atherosclerotic risk markers with rather unexplored connections with A. muciniphila colonisation patterns in human subjects.
The effect of essential oil of rosemary on eccentric exercise-induced delayed-onset muscle soreness in non-active women
Authors: Rezaee M. , Hajiaghaee R. , Azizbeigi K. , Rahmati-Ahmadabad S. , Helalizadeh M. , Akbari M. , Farzanegi P. , Azarbayjani M.-A.
Published: September 2019

Muscle soreness is a problem associated with physical activities. Recently, the medicinal herbs are strategies to prevent muscle soreness. The present study aims were to determine the effect of rosemary essential oil on the responses of lactate dehydrogenase, creatine kinase (CK), lymphocytes, neutrophils, muscle swelling (MS) and muscle pain (MP) following eccentric leg curl exercise in non-active women. 24 non-active females voluntarily participated in this study and were randomly assigned into three groups: rosemary dose 1 (RD1) (n=8; 0.25 ml), rosemary dose 2 (RD2) (n=8; 0.5 ml) and placebo (n=8; 0.5 ml olive oil). Participants in supplement groups consumed the desire amounts of rosemary essential oil every 8 h per day for 14 days. Then, the eccentric leg curl exercise was performed. The supplementation continued until 72 h after exercise. The serum variables, as well as, MS and MP were measured before, 24, 48 and 72 h after exercise. Data were analysed using repeated measure analysis of variance and P≤0.05 considered as significant. The results showed that rosemary significantly decreases CK in RD2 compared with placebo and RD1 48 h after exercise. There was no other significant difference in other serum variables. In conclusion, the present study showed a beneficial effect of rosemary on 48-h post-exercise serum CK concentration (a muscle damage indicator).
Risk assessment of mycotoxins in stored maize: case study of Shandong, China
Authors: Dong Y. , Fan L. , Liang J. , Wang L. , Yuan X. , Wang Y. , Zhao S.
Published: September 2019

Risk characterisation of dietary exposure of aflatoxins (AFs), fumonisins (FBs), deoxynivalenol (DON), zearalenone (ZEA) in maize from Shandong Province was conducted in this study. A total of 520 maize samples were collected after harvesting in 2014 and 2015 from 26 selected villages in Shandong Province, China. A deterministic approach was used in the current study. The dietary intake data of maize was obtained from ‘Shandong Statistical Yearbook 2018’. The risk characterisation of FBs, DON, and ZEA was evaluated in 4 population groups (2 to 6-year-old children, standard adults, city adults and village adults) based on probable intake. 2 to 6-year-old children and adults were exposed to FBs (0.42 and 0.20 μg/kg body weight (bw)/day), DON (0.04 and 0.019 μg/kg bw/day), and ZEA (0.0024 and 0.0011 μg/kg bw/day) through mean maize consumption in diets, which was lower than the provisional maximum tolerable daily intake of each mycotoxin established by JECFA. Risk assessments showed a low risk for liver cancer due to consumption of aflatoxin B1 (0.027-0.21 cases per 100,000 persons per year) contaminated maize compared with China’s current liver cancer incidence of 24.6 cases per 100,000 persons per year.
Ochratoxin A challenges the intestinal epithelial cell integrity: results obtained in model experiments with Caco-2 cells
Authors: Alizadeh A. , Akbari P. , Varasteh S. , Braber S. , Malekinejad H. , Fink-Gremmels J.
Published: September 2019

Contamination of human and animal diets with different mycotoxins have gained significant attention over the past decade. The intestinal barrier is the first site of exposure and a primary target for nutritional contaminants and hazardous substances including mycotoxins. In this study, the potential impact of ochratoxin A (OTA) on intestinal barrier integrity was highlighted using a human intestinal Caco-2 cell line. Cell viability following OTA exposure was determined by lactate dehydrogenase release and the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Moreover, markers of barrier integrity, such as transepithelial electrical resistance (TEER) as well as the permeability of Lucifer Yellow (LY) and fluorescein isothiocyanate (FITC)-dextran, were assessed. Furthermore, the protein expression of different tight junction (TJ) proteins, as main constituents of barrier integrity, was evaluated by Western blot. Results show that OTA reduces TEER values in a concentration- and time-dependent manner and increase the permeability of LY through the intestinal epithelial layer, while the cell viability did not change significantly. However, the damage was not severe enough to change the permeability to larger molecules, such as FITC-dextran. OTA exposure down-regulated the expression of TJ proteins claudin-1, -3 and -4 and up-regulated the expression of zona occludens 1. The observation that OTA can disrupt the epithelial barrier is of clinical importance as it may lead to an increased passage of luminal antigens into the systemic circulation.
Metronidazole induced encephalopathy: case report and discussion on the differential diagnoses, in particular, Wernicke's encephalopathy
Authors: Hou Wenlu , Yiin Raphael Shih Zhu , Goh Chin Kong
Published: September 2019

Metronidazole induced encephalopathy is a rare central nervous system toxicity, which may be completely reversible with prompt cessation of metronidazole usage. We present a case of metronidazole induced encephalopathy in a 59-year-old man with a history of Whipple's procedure for pancreatic neuroendocrine tumour. The characteristic magnetic resonance imaging features of metronidazole induced encephalopathy and its main differential diagnosis, Wernicke's encephalopathy, are discussed.
Effect of Augmented Reality and Simulation on the Achievement of Mathematics and Visual Thinking Among Students
Authors: Aldalalah Osamah Mohammad , Ababneh Zyad , Bawaneh Ali , Alzubi Wafa
Published: September 2019

The purpose of this study was to investigate the effect of augmented reality and simulation on the achievement of mathematics and visual thinking among students. The study sample consisted of 86 students of mathematics divided into two treatments in a random way. This study utilized the quasi experimental type of methodology. The independent variables were the instruction (augmented reality & simulation). The dependent variables were the students’ achievement and visual thinking. The findings of this study showed that students using the augmented reality mode performed significantly better than those in the simulation mode in achievements and visual thinking.
Effectiveness of Digital Note-Taking on Students’ Performance in Declarative, Procedural and Conditional Knowledge Learning
Authors: Sun Dan , Li Yan
Published: September 2019

Note-taking is an ever-present learning activity in students’ daily lives, and an increasing number of mobile terminals have been integrated into curricu-lums. However, the effectiveness of the use of digital note-taking on mobile terminals on students’ learning has not been deeply explored. The purpose of this study is to evaluate how digital note-taking using mobile terminals af-fects student performance, with particular regard to declarative, procedural and conditional knowledge learning. A quasi-experiment was conducted for three months among 72 first-year high school students from a computer sci-ence (CS) course. In the study, students in the experimental group (n = 40) recorded notes digitally, whereas the students in the control group (n = 32) used the conventional approach (i.e., recording handwritten notes). The re-sults indicate that the students who recorded notes digitally scored signifi-cantly higher than those who recorded notes conventionally. The students who were designated as “excellent,” and those who were designated as “low-performing,” were most likely to benefit from this new method of note-taking.
An Effective Allocation Model of Computer Teaching Management Resources Based on Particle Swarm Optimization
Authors: Yang Xiang
Published: September 2019

This paper attempts to improve the resource utilization in computer teaching, striking a balance between educational resource and education development. For this purpose, the author systematically investigated the allocation of computer teaching management resources, and set up an effective allocation model of such resources based on particle swarm optimization (PSO). The research results show that the PSO-based model can coordinate the allocation of computer teaching management resources, enhance the utilization rate of teaching resources, and prevent resource waste. With the aid of the proposed model, the imbalance between different counties and districts in the number of computers and teachers was greatly improved, which contributes to the coordinated development of education in the study area. The research findings have great theoretical and social significance for the sustainable development of education and the improvement of the education system.
Application of a New Cultivation Model in an Undergraduate 'Convention and Exhibition Management' Study Program
Authors: Zhang Hui , Zhang Rongteng , Yin Jie
Published: September 2019

Convention and exhibition management is a practical and emerging new major in colleges and universities. Students are required to master strong practical and comprehensive coordination skills. However, the professional demand of the convention and exhibition industry cannot be met under the traditional general education training model. Hence, the present study combines the professional work-oriented undergraduate training with the cooperative education concept and proposes the industry accreditation plus government advisory cooperative undergraduate training model. In addition, a school–enterprise dual-element student training system is built. The key realization path of the "four in one" of the government, school, industry, and students with students as the core is carried out combined with path–goal theory. The cultivation model proposed in this paper is approved and recognized by both students and enterprises. The reformed cultivation model improves the overall quality of graduates and the satisfaction of employers. This model can better meet the expectations from graduates of convention and exhibition majors in modern society compared with the traditional education model.
A Survey of Attention Deficit Hyperactivity Disorder Identification Using Psychophysiological Data
Authors: De Silva Senuri , Dayarathna Sanuwani , Ariyarathne Gangani , Meedeniya Dulani , Jayarathna Sampath
Published: September 2019

Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common neurological disorders among children, that affects different areas in the brain that allows executing certain functionalities. This may lead to a variety of impairments such as difficulties in paying attention or focusing, controlling impulsive behaviors and overreacting. The continuous symptoms may have a severe impact in the long-term. This paper discusses the existing literature on the identification of ADHD using eye movement data and fMRI together including different deep learning techniques, existing models and a thorough analysis of the existing literature. We have identified the current challenges and possible future directions to provide computational support for early identification of ADHD patients that enable early treatments.
Assessment of Friction Behavior with Surface Location Error Analysis in Milling Process
Authors: Rafan N.A. , Ab Rashid Siti Nur Madihah , Jamaludin Z.
Published: September 2019

Accurate roundness or circularity measurement is essential to obtain correct functioning of assemblies, making roundness an important quality control parameter in manufacturing industry. Since circular motion while milling a circular work piece leads to quadrant glitches, a phenomenon familiar with existence of highly nonlinear friction behavior, roundness measurement was conducted to investigate this surface location error due to feed rate of the moving work table. This paper presents friction behavior on a milling process circular work piece in line resulted from identified surface error location (SLE).
Effects of Pitch of Array Punch on the Nanoimprinting
Authors: Lin Yuan Ching , Hsiao Chen Yuan
Published: September 2019

In this study, molecular dynamics (MD) are used to simulate the nanoimprinting behaviors of (001) Ni thin films using 3×3 array cuboid diamond punch. Different pitch of the punches was used to investigate the effect of the interaction among the forming pattern and the quality of the formed holes. Forming force was evaluated including normal and tractional force of the punch during pressing process. The dislocation behavior was also monitoring during the holes forming. The result showed that the pitch of the punch was 2w could get the best forming pattern.
Wellens’ syndrome: a case report with atypical features
Authors: Ghizzoni Giulia , Sciatti Edoardo , Vizzardi Enrico , Bonadei Ivano , Fabbricatore Davide , Metra Marco
Published: September 2019

Wellens’ syndrome is a pattern of electrocardiographic T-wave changes seen in the precordial leads in patients with unstable angina. Two different patterns have been described. Type A presents with biphasic T-waves in V2-V3 and type B presents with symmetrical deep T-wave inversions in V2-V3. The etiology is related to a critical stenosis in the proximal left anterior descending artery (LAD). We describe a patient who presented at our emergency department with intermittent chest pain and showing Wellens’ pattern T-wave inversions in the precordial leads of the electrocardiogram. She was found to have 95% stenosis in mid LAD.
Association between reduced brain-derived neurotrophic factor concentration & coronary heart disease
Authors: Sustar Aleksandra , Perkovic Matea Nikolac , Erjavec Gordana Nedic , Strac Dubravka Svob , Pivac Nela
Published: September 2019

Background & objectives:

Brain-derived neurotrophic factor (BDNF) facilitates neuronal survival, differentiation and synaptic connectivity and affects neurotransmission throughout the brain. However, it has also a modulatory role in energy homeostasis, obesity and cardiovascular function. Obesity, high body mass index (BMI) and dyslipidaemia, among other factors, contribute to coronary heart disease (CHD) development. The exact role of BDNF in development of CHD is not well defined. This study was aimed to evaluate if plasma BDNF concentration was associated with CHD in ethnically homogeneous groups of patients and to correlate plasma BDNF levels with known risk factors for CHD.

Methods:

Plasma BDNF concentration, BDNF Val66Met polymorphism and other biological and anthropological risk factors for CHD were determined in 208 patients with CHD and 156 healthy controls.

Results:

Plasma BDNF concentration was significantly (P<0.01) reduced in patients with CHD compared to controls, and it was not influenced by gender, age, smoking or BDNF Val66Met polymorphism. It was considerably correlated with cholesterol (P=0.004), low-density lipoprotein (P=0.006), and diastolic blood pressure (P=0.018) in patients with CHD and with platelet number (P=0.003) in healthy controls.

Interpretation & conclusions:

The results revealed lower plasma BDNF concentration in patients with CHD, suggesting that decreased plasma BDNF concentration might be associated with CHD pathogenesis. Longitudinal studies with a large sample need to be conducted to confirm these findings.
Serovar diversity of Salmonella among poultry
Authors: Kumar Yashwant , Singh Varun , Kumar Gulshan , Gupta Naveen Kumar , Tahlan Ajay Kumar
Published: September 2019

Background & objectives:

Salmonellosis due to the consumption of contaminated poultry products is a well-known public health concern, and assessing the distribution of Salmonella serovars among poultry becomes important for better prevention and control. The objective of the present study was to assess the distribution of Salmonella serovars among poultry.

Methods:

The isolates received at National Salmonella and Escherichia Centre during 2011-2016 were subjected to biochemical identification, followed by serological characterization to identify the Salmonella serovars, and the data were presented to exhibit the distribution of Salmonella serovars among poultry.

Results:

Salmonella was found to be present in poultry in all the regions included in the study. Salmonella Typhimurium, S. Gallinarum and S. Enteritidis were the most prevalent serovars accounting for 96.2 per cent of isolates. Salmonella was identified in poultry from all major egg-producing and egg-consuming States. Other serovars which were scantly identified included S. Infantis (2.7%), S. Montevideo (0.64%), S. Newport (0.26%) and S. Pullorum (0.13%).

Interpretation & conclusions:

Diverse distribution of Salmonella serovars in poultry in India, with known potential to infect human population and/or other poultry flocks, requires urgent nationwide stringent control measures.
Safety & efficacy of an intravasal, one-time injectable & non-hormonal male contraceptive (RISUG)
Authors: Sharma Radhey Shyam , Mathur Ajit Kumar , Singh Rajeev , Das Hem Chandra , Singh Gulshan Jeet , Toor Devinder Pal Singh , Guha Sujoy Kumar
Published: September 2019

Background & objectives:

For improved male contraception, a new polymeric drug molecule – Reversible Inhibition of Sperm under Guidance (RISUG) has been synthesized and has been found to be effective, safe and reversible in various animal species. Phase-I and phase-II clinical trials have confirmed its safety and contraceptive efficacy. The present study was undertaken as a multicentric-limited phase-III clinical trial to test the efficacy and safety of RISUG in human volunteers.

Methods:

One hundred and thirty nine young males each having at least two children and living with wife were given 120 μl of RISUG as bilateral vas intraluminal injection. After the single-dose administration, the individuals were followed in respect of general health and semen parameters. Their wives were also followed particularly to determine onset of pregnancy.

Results:

During the six month follow up, the health of male volunteers and their wives was normal with no significant adverse effects. Temporary scrotal enlargement and mild scrotal and inguinal region pain were manifested in most individuals and resolved within one month without any routine activity impairment. In six individuals, there was injection procedure failure and azoospermia was not achieved. The other 133 individuals had either severe oligozoospermia or azoospermia at the first semen examination one month following RISUG injection; 82.7 per cent individuals had continued azoospermia in the month following first semen examination onwards and the rest 17.3 per cent manifested azoospermia within three to six months.

Interpretation & conclusions:

RISUG intravasal injection appears to be a safe clinical procedure with no significant adverse effects and has high sustained contraceptive efficacy. The localized intervention and continued contraceptive action on single-dose administration were significant features of the RISUG technology.
A new manoeuvre of vascular control in laparoscopic spleen-preserving distal pancreatectomy
Authors: Jie Zhu , Hong Li , Bin Zhang , Haibiao Wang
Published: September 2019

Background:

The aim of this study is to explore a new manoeuvre of vascular control technique in laparoscopic spleen-preserving distal pancreatectomy (LSPDP).

Materials and Methods:

A total of 63 patients were diagnosed with pancreatic tumour in our hospital from January 2013 to December 2018. In these cases, Kimura technique was utilised in 33 patients and total blood flow blocked technique was used in 30 patients. The clinical data of these 63 patients of were retrospectively analysed.

Results:

Four groups of patients were operated smoothly. In Kimura group, 33 patients were carried out using Kimura technique. Four patients' spleens were resected because the spleen artery was damaged. Three patients among them were converted to open surgery. In the other group, one patient was converted to open and resected the spleen. When comparing the Kimura group with the last series group, the mean surgical time decreased by 27 min, the estimated blood loss decreased by 108 ml, which had a significant statistical difference, whereas postoperative haemorrhage and postoperative pancreatic fistula had no statistical difference.

Conclusion:

After ten patient's practice, application of new manoeuvre of vascular control technique in LSPDP is feasible and safe, with advantages of less blood loss and shorter operation time.
Metamorphōsis Between Ovid, The Theōsis Of Andrew Of Crete And The Byzantine Humanism Of Leo Vi
Authors: Bogataj Jan Dominik
Published: September 2019

The paper addresses the Greek term μεταμόρφωσις, which links Ovid’s famous Metamorphoses with Christ’s transfiguration on the mountain (Mt 17:1–8; Mk 9:2–8; Lk 9:28–36). In addition to early Jewish mystical and apocalyptic traditions, it is Greco-Roman pagan literature that may be identified as a source for this gospel account. The latter went on to elicit a rich patristic and Byzantine response (Andrew of Crete, In transfigurationem 1 [Or. 7]; Leo VI the Wise, Hom. 10.11.39), which is the focus of the present study. The comparison of literary genres, philological and semantic analysis of the term μεταμόρφωσις, and confrontation of the different influences reveals the crucial difference between the two general contexts (pagan and Christian), at the same time enhancing our understanding of both. While Ovid’s numerous apotheoses are recognised as an important contribution, they differ from the patristic term θέωσις in their lack of inner, spiritual transformation.
Ovid: Dido Writing to Aeneas (Heroides 7)
Authors: Zupančič Polonca
Published: September 2019

Pesem je del Ovidijevih Heroid, niza ljubezenskih pisem v verzih, ki so izrazito dvodelna: prva serija pisem, ki jih svojim ljubimcem ali oddaljenim možem pišejo slavni ženski liki (najbolj znane dvojice so npr. Penelopa in Odisej, Dejanejra in Herkul, Ariadna in Tezej, Medeja in Jazon ter Didona in Enej), spada v zgodnje obdobje Ovidijevega ustvarjanja; datirajo jih v čas pred letom 15 pr. Kr. Drugo skupino, od 16. do 21. pisma, pa sestavljajo pisma treh zaljubljencev z odgovori izbranih žensk (npr. Paris in Helena); slednja so verjetno nastala v letih 4 do 8, tik pred Ovidijevim izgonom iz Rima.
Acoustic characteristics of vocalisations emitted by the domestic rabbit (Oryctolagus cuniculus) during copula ejaculation and electro-ejaculation with or without anaesthesia
Authors: Orihuela A. , Ungerfeld R.
Published: September 2019

Vocalisations can be used as reliable indicators of pain, but little information is available in rabbits, where acoustic tools for farming environments can be used for welfare judgements. The aim of this study was to compare vocalisations produced during copula ejaculation and electro-ejaculation (EE), with or without general anaesthesia, in domestic rabbits. Vocalisations of nine New Zealand white adult males were digitally recorded. The number of males vocalising and vocal characteristics including high, low, maximum and fundamental frequencies and duration of the vocalisations were analysed. There were no differences in the number of males vocalising or any vocalisation parameter between the 1st and 2nd ejaculation while copulating, even though the fundamental frequency increased in all males in the 2nd ejaculation (P=0.008). More males vocalised while mating than while being electro-ejaculated (P=0.03), and all vocalisation parameters were greater during EE than while mating (P=0.004). The use or not of anaesthesia during EE did not modify any of the parameters evaluated. It was concluded that: 1) more males vocalised during copula ejaculation than while being electro-ejaculated; 2) bio-acoustic analysis allowed us to identify aversive utterance vocalisations, which are characterised with higher frequencies, that those from non-aversive stimulus; and 3) at least with the anaesthetic combination and the responses studied, anaesthesia had no effect on the acoustic characteristics of the vocalisation emitted during EE in rabbits.
Influences of environment on the development and lifetime reproductive performance in domestic rabbit females
Authors: Savietto D. , Martínez-Paredes E. , Pascual J.J.
Published: September 2019

Environmental insults of different nature and intensity, such as fluctuation in the air temperature, which can affect access to food, its quality and diseases, are a reality in any livestock system. This is much more important when the insults occur in early life, conditioning the development and adult life of animals. In ecology, for instance, it is widely accepted that high quality offspring are more reactive against predators, occupy better territories and find more mates, resulting in longer lives and greater fitness. It is also a given that adults exposed to famine or disease as juveniles have shorter lives and produce fewer offspring. To determine whether the environment influences the development and lifetime reproductive performance of rabbit females, we designed an experiment combining two factors: nest and pubescent development. Nest development was measured by recording the average daily gain of 864 females during suckling and during their pubescent life (63 to 184 d old), and body development was conditioned by providing animals a high-energy control (C) or a fibre-rich (F) diet. However, in the course of the study, 191 of the 864 pubescent females were exposed to rabbit haemorrhagic disease (RHD). This unexpected environmental insult was considered as a third experimental factor influencing the reproductive performance of rabbit females. Contrary to expectation, fast suckling gain impairs reproductive lifespan, resulting in fewer newborn kits produced in a female lifetime. Although females on diet F lived 37 d longer than females on diet C, this difference was only perceived in their pubescent life. In addition, the exposure to RHD interacted with suckling gain (SG). Exposed females with a fast SG produced more kits as adults, but in the absence of the virus, high SG females produced fewer newborn kits. These results open new insights into the management of future breeders during nesting and pubescent life.
Abstracts of the 18th French Rabbit Days
Authors: Conferences, Congresses, Symposiums... Abstracts,
Published: September 2019

The 18th edition of the French Rabbit Days (Journées de la Recherche Cunicole) was organized by the association CUNICULTURE, in association with the INRA (Institut National de la Recherche Agronomique) and the ASFC (French Branch of the WRSA), in Nantes, during one and a half days 27-28 May 2019. A total of 32 peer reviewed communications, including 3 synthesis, were orally presented to about 90 attendants. The 2 most relevant subjects were 1/ studies on and possibilities of control of the viral haemorrhagic disease caused by the new RHDV2, and 2/ control of digestive disorders, particularly coccidiosis, with nonchemical feed additives or diet formulation. One part of the communications was also devoted to the efforts made for the promotion of rabbit meat in France and to the comportment of consumers in relation with rabbit meat. The full texts of the communications, in French, are available on the WRSA website at the URL : http://world-rabbit-science.com/Other-Proceedings/2019-18th%20Rabbit%20Days/000-E-Book-JRC2019.pdf