bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALYSIS OF SCIENTIFIC RESEARCH ON CLINICAL APPLICATIONS OF L-CARNITINE IN PEDIATRIC PRACTICE
Authors: Davydenko A.V.
Published: December 2023

The L-carnitine molecule was discovered 115 years ago by two scientists, Prof. R. P. Krimber and Prof. V. S. Gulevich. In 1962, the role of carnitine as a carrier of long-chain fatty acids into the mitochondria through their internal, highly selective membrane was discovered. L-carnitine is a vital compound that plays a crucial role in fat metabolism and energy metabolism in the child's body. The purpose of the study is to analyze the literature data on the current features of the clinical and pharmacological substantiation of the use of L-carnitine in pediatric practice. The article discusses aspects of the use of L-carnitine in pediatric medicine. L-Carnitine, essential for fatty acid metabolism, is synthesized endogenously and obtained from dietary sources. Ninety-eight percent of it is accumulated in skeletal muscles. its critical role in primary deficiencies, such as systemic encephalomyopathies and isolated myopathies, is unequivocal. L-Carnitine modulates glucose metabolism and increases the activity of respiratory chain enzymes. In addition, it acts as an antioxidant, preventing oxidative damage and inhibiting apoptosis, a signal in response to oxidative stress. Studies show that L-carnitine may be beneficial for children with metabolic disorders, athletes, and other categories of patients. However, it is important to consider dosage, safety, and potential side effects. Thus, the accumulated clinical experience of L-carnitine use indicates various positive effects and allows us to consider it an effective preventive and therapeutic agent that can be used in the pediatric population. Its applications extend to scenarios requiring energy support during heightened mental, emotional, and physical stress, as an adjunct therapy for diverse somatic diseases, during post-illness rehabilitation, and for bolstering immune reserves.
PECULIARITIES IN CORRECTING ANXIETY AND DEPRESSIVE DISORDERS IN CARE-GIVERS FOR SERIOUSLY ILL PATIENTS WITH CANCER
Authors: Vasylyeva G.Yu. , Strashko E.Yu. , Kundii Zh.P.
Published: December 2023

The challenges faced by families of patients with cancer can be categorized into three main groups: emotional disorders in caregivers, behavioral changes, and problems related to the care and treatment system. Emotional disorders encompass anxiety, uncertainty about the patient's health, and a pervasive sense of helplessness. Behavioral changes involve shifts in family roles and lifestyle, intensified care-giving responsibilities, particularly in the later stages of treatment, and financial hardships stemming from the costs of anticancer treatment. Systemic challenges in care and treatment further compound the difficulties experienced by the family unit. Anxiety and depressive disorders were detected in 69.3±3.8% of relatives of patients with malignant neoplasms. To correct emotional disorders in caregivers for patients with cancer, a correctional complex was proposed, which included a combination of rational, short-term positive, cognitive-behavioral and family psychotherapy with psychopharmacotherapy. Under the influence of the proposed complex for the correction of anxiety-depressive disorders in caregivers, a significant decrease in the severity of symptoms of depression (MADRS, p<0.05) and anxiety (HAM-A) was noted after 4 weeks. This was clinically manifested by a subjective improvement in mood, a decrease in the amplitude of fluctuations in affective disorders, diminished signs of emotional labiality, improved sleep, increased productivity in everyday activities, and a reduction in signs of anxiety. The proposed intervention demonstrated its efficacy in positively impacting the well-being of caregivers, highlighting the importance of a multifaceted approach to address the complex challenges faced by families in the context of cancer care.
Regulatory and Legal Bases of Digitalising Book Monuments of Ukraine
Authors: Koleko Mykhailo
Published: December 2023

The aim of the article is to analyze the laws of Ukraine, the resolutions of the Cabinet of Ministers of Ukraine, the Orders of the Ministry of Culture and Information Policy of Ukraine in the context of their defining the normative and legal bases of working with book monuments of Ukraine. The article studies the settlement of the issue of Ukrainian book heritage digitization as a tool for its preservation and popularization.

Research methods involve a combination of analysis and synthesis methods in their dialectical interaction, as well as methods of empirical and theoretical research, and system and structural analysis.

The scientific novelty of the study consists in highlighting the presence of legal grounds in the current regulatory and legal base of Ukraine for the implementation of the technology of digitalizing Ukrainian book monuments, and working out ways to bring the legal field of Ukraine closer to the EU standards in terms of rare books digitization.

Main conclusions. Book monuments of Ukraine are of great importance for the national identity formation. The demand for the formation of a stable Ukrainian identity has increased after the full-scale russian invasion of Ukraine in 2022. Under these conditions, the protection of the spiritual heritage of Ukraine has become a matter of national security, taking into account the fact that it is impossible to form a national identity without it. In conditions of the active formation of a digital society, the opportunities for preservation, study and presentation of cultural monuments in the modern cultural sphere grow rapidly. Digitization technology is an effective tool for preservation and protection of book monuments, opens the way to their unhindered promotion in modern information space. In this article, the importance of protecting book monuments of Ukraine through the digitization technology introduction in conditions of the russian-Ukrainian war is emphasized. It is established that the existing regulatory and legal bases ground the legitimate foundation for the book monuments digitization. The prospects for improving the legal sphere of Ukraine in terms of its approximation to the standards of the European Union are clarified.
Modern Fundraising in Libraries of Foreign Countries
Authors: Tsilyna Maryna
Published: December 2023

The aim of the article іs to find out the specifics of fundraising in libraries of foreign countries, and determine prospects for further implementation of such activities in Ukraine.

Research methods combine a set of general scientific methods of studying problems. In the process of studying professional and profile literatureі and determining the theoretical basis of scientific research, the survey-analytical method was applied. With help of the systematic method, single foreign practices of library fundraising were analyzed. The use of the induction method made it possible to generalize the studied material and draw conclusions about the implementation of experience of other countries in Ukrainian library institutions. The scientific article is based on the principles of objectivity and integrity.

Scientific novelty consists in defining the main forms and means of modern fundraising interaction in the field of library activity.

Main conclusions. A significant role in fundraising cooperation in the library field is played by well-established ties in the sphere of international culture, as mutual support and fundraising financing strengthen the national base of any state in another country. Various events holding, such as conferences, seminars, concerts and meetings, as well as active involvement of social networks, creation of separate web pages on library websites, effectively contribute to charity. The EU provides many direct and indirect financial opportunities for the development of book collections on its territory. ESIF are the most important source of European indirect funding. In modern Ukraine, the domestic content of book collections is actively integrated into the European space, which, in particular, proves the fundraising activity of “Ukrainian book without borders” and “Librarians of Ukraine and Germany – together to Victory” projects.

We hope that the existing examples of international cooperation in the library industry serve as a model for the implementation of further similar projects on the domestic base, and, at the same time, for the popularization of Ukrainian books abroad. In general, international fundraising in library activities in modern world is a promising investment in future spirituality.
Linear Active Disturbance Rejection Lateral Controller for Unmanned All-Terrain Vehicle
Authors: Zeng Dequan , Hu Yiming , Jiang Zhiqiang , Feng Wanqiang
Published: December 2023

Abstract: To address the disturbance of model uncertainty, a linear active disturbance rejection controller (LADRC) was designed for robust lateral control of unmanned all-terrain vehicle. In terms of relative motion of target node and current state, first-order lateral tracking model is established. According to the developed model, linear tracking differentiator (LTD), linear extended state observer (LESO) and linear state error feedback (LSEF) are designed in turn. LESO could observe the uncertainty of system and LSEF could compensate the uncertainty to make system robust. In order to verify the effectiveness, two typical scenarios, circle and double lane tracking, were designed for test. And the uncertainties of wheelbase and steering ratio were considered. Results illustrate that the designed LADRC can stably control the unmanned all-terrain vehicle tracking reference trajectory under both scenarios and has the advantages of small tracking error and small overshoot compared with the conventional pure tracking methods.
Variability of Pedunculate Oak (Quercus robur L.) Provenances in Central Ukraine
Authors: Neyko I. , Matusyak M. , Neyko O. , Tsyhanska O.
Published: December 2023

A total of 65 pedunculate oak (Quercus robur L.) provenances from the southern, central, northern, and eastern parts of the oak distribution range in Vinnytsia region (Central Ukraine) were assessed in a common garden experiment. Analysis of the population’s survival dynamics indicates an increase with age in the adaptive capacity of the provenances to the environmental conditions. In the initial stage, up to 10 years, the survival rate of the local populations was about 75%, by 40 years the survival decreased to 15%. At the same time, the number of trees of other provenances, which were characterised by higher survival rate, increased. The best adaptive capacity was obtained for the Rivne (Ostrozke), Kirovohrad (Svitlovodske), Chuvash (Kanaske), and Ulyanovsk (Melekske) provenances. The indicators of average height of the trees and geographic longitude (r=-0.513) and latitude of the natural growth of the populations (r=-0.474) are characterised by a significant and moderately close relationship. Oak populations differ by average diameter and remoteness from the natural location ratio (r=-0.431), and by the geographic latitude of their growing place (r=-0.478) in a moderate correlation. According to the comprehensive assessment of the non-local populations, which included survival rate, mean diameter and height, and tree breeding category, we can conclude that in general, the central populations have optimal values. Populations of Bryansk, Khmelnytskyi, Zaporizhzhya, and Cherkassy origin, as well as the local ones, have the highest values. The lowest indicators were observed manly for the northern oak populations.
Wood Colouring with Natural Dye Extracts. New Research and Perspectives
Authors: Beldean E. , Timar M.C.
Published: December 2023

The aims of the present research were to test new types of natural dye extracts for wood as a possible alternative to synthetic dyes and to evaluate the colour changes after a period of one year of exposure to natural light, in indoor conditions. Three types of extracts using raw materials: nutshell from Juglans regia L. (E1), onion peels (E2), and dry plant of Chelidonium majus L. (E3) were employed. Spruce wood (Picea abies L. Karst) samples with dimensions of (120x80x5) mm were used. The dye aqueous solutions with a concentration of 5% (E1, E3) and 2.5% (E2) were obtained by solid-liquid extraction at 100°C for three hours. The extracts E1, E2, E3 were modified by the addition of mordant ferrous sulphate Fe2(SO4)3 3% and coded EM1, EM2, EM3 respectively. The wood was coloured by dipping procedure at 60° C for 30 min. Three replicates were employed for each type of dye solution. After conditioning, two replicates together with the uncoloured samples (M) were further exposed indoors, and one coloured sample remained unexposed, as a control. Colour measurements in the CIELab system were performed before and after each period of exposure (30, 60, and 365 days), and the colour differences ΔL, Δa, Δb, and ΔE were calculated. Generally, all the samples dyed with natural extracts had fewer colour differences compared with the uncoloured wood. The lower value for colour change was registered for the E2 extract, followed by the E3, and E1 extract, respectively. According to the exposure time, the colour differences values ΔE range correspond to a medium colour up to different colours in visual perception. For mordant dye extracts EM1, EM2, and EM3 the results indicated a different colour in visual perception. The ΔE values registered were even higher than the uncoloured samples (M). The results were in accordance with similar research in the field. The present study opens new research opportunities in wood finishing and new colouring perspectives with eco-friendly dyes.
Material Resistance and Moisture Dynamics of Beech Wood (Fagus orientalis)
Authors: Daryaei M.G. , Moradi Z. , Fathi L. , Hasanagic R. , Humar M. , Bahnani M.
Published: December 2023

In this paper, the natural durability of commercial wood (beech wood) was studied by measuring its water exclusion efficacy and durability against fungi. This information was utilized in the Meyer−Veltrup model to calculate the resistance dose. The results showed that Fagus orientalis (Lipsky) heartwood and sapwood were less durable (DC 4−5). After one hour of immersion, the water uptake in F. orientalis sapwood was 19%, slightly more than that determined with F. orientalis heartwood (18.9%). Water immersion after 24 h was highest for F. orientalis sapwood (45.4%), followed by F. orientalis heartwood (40.9%). Up to 54.2% median MLF on F. orientalis heartwood and up to 61.1% median MLF on F. orientalis sapwood were attributed to the white fungus T. versicolor. In contrast, the lowest median MLF was caused by F. orientalis heartwood and sapwood by the white fungus H. fragiforme. 35.4% median MLF on F. orientalis was caused by terrestrial microcosms. Based on the resistance model, the first signs of fungal decay on F. orientalis heartwood and sapwood wood will develop after 312 and 294 days of favorable conditions, respectively.
Didactic Strategy Proposal for Initial Research Training
Authors: Robaina Aguirre E.M. , Valdes Pedroso M.
Published: December 2023

The objective of this research is to propose a didactic strategy for the investigative training process of the students of the higher technician in Sports Training at the University of Artemisa, which responds to current demands. The investigative approach is presented as its general strategy. The mode of action. The diagnosis of the initial state is presented which reveals the existence of the research problem. Theoretical, empirical, and statistical methods were used. The results obtained in the indicators of the variable from its practical application and the experts' criteria manifest the feasibility and potential of the Didactic Strategy, evaluating it as very appropriate.
The Impact of Physical Exercises on the Psychomotor Capacities of Middle School Pupils
Authors: Ghica B. , Onoi M. , Ionescu M.-L.
Published: December 2023

The research aims to identify the adolescents’ avoidance causes from physical education lessons and to determine the means of improving students' satisfaction with physical education. The present research is of ascertaining – ameliorative type, carried out on a sample of 15 teachers and 180 pupils from secondary classes in the Secondary School "Alexandru Ioan Cuza" and the Secondary School no 10 Bacau, Romania, between March 1, 2022 and June 10, 2022. The methods used in the research included: the analysis of the specialized literature, the diagnosis questionnaire, and the mathematical-statistical method. The main conclusions refer to the identification of the passionate fields and the preferences for the sport of the pupils, the argumentation of the need to introduce in the physical education and sports classes competitive sports games, which, besides the training of some motor qualities, ensure an extremely complex set of psychic sentimental, emotional, volitional and cognitive nature acquisitions.
Improving Speed in Primary School Pupils using Integrated Dynamic Games
Authors: Macovei R.A. , Popescu V.
Published: December 2023

Current primary education aims at the multilateral development of students using means that interconnect the subjects studied so that they outline a wide range of key competencies at the end of the cycle. The present research seeks to find didactic solutions, experimentally confirmed, and transposed by the application of dynamic games, to improve the speed motor quality cumulative with the consolidation of the competencies formed within other disciplines, thus, capitalizing on the multifunctional solution of new learning situations. The study was applied to 54 students from 3rd and 4th grades in rural areas, divided into 2: a control group and an experimental group. In the school year 2021-2022, the experimental group went through a program containing integrated dynamic games for the development of speed motor quality, solving at the same time certain requirements with interdisciplinary approaches. The obtained results confirm the validity of the hypothesis by improving more obvious the speed motor quality of the students from the experiment group as a result of the implementation of the integrated dynamic game program. The study also highlights that a reorganization of activities must be made so that the student can demonstrate interconnections to respond promptly to the tasks imposed by the future society.
Physical Exercise as Leisure Activities in Youth's Lives
Authors: Nanu M.C. , Brabiescu Calinescu L. , Pascu D. , Cosma M.A.
Published: December 2023

Despite the known benefits of physical activity, there is a worldwide trend towards less daily physical activity. According to the latest Eurobarometer, 63% of the population of our country never do physical exercises or sports, placing them at the bottom of the ranking of EU countries. The present study aims to identify the share of physical activities in the free time budget of young people. Thus, it is desired that, through a sociological investigation, to investigate whether young people in the Oltenia area actively spend their free time. Methods. The research was carried out between April and June 2022 and consisted of the development, transmission, and interpretation of the data of a questionnaire applied in the online system, on the google.doc platform. The questionnaire contained 15 items referring to the free time of young people, which were answered by 71 young people under conditions of anonymity. Results. Most respondents exercise occasionally in their free time, with the frequency of exercise positively correlating with the perception of physical appearance (r=0.45, p
The Role of Occupational Therapy in People with Mental Health
Authors: Anghel M. , Botoc L.D.
Published: December 2023

Unfortunately, in our country, in some situations, the level of occupational therapy activities is limited to the precarious material conditions in different types of institutions. Despite the current improvements, there is still an acute need for adequate spaces and materials to carry out quality occupational therapy activities. The presence of these negative aspects, which is added to the lack of qualified personnel in the field, diminishes the quality of the recovery process in the institutions. The scientific challenge that is the subject of this paper is to highlight the role of occupational therapy in the exploration of specific resources for institutionalized persons, necessary for the development of autonomy. The objective of the research is to implement an intervention program, through remedial activities, that will contribute to direct involvement in daily life for people with mental health problems. The main conclusion of the research is that by applying remedial activities adapted to the specific needs of the client, the components of occupational performance can be improved, by increasing the degree of involvement in daily activities for institutionalized people.
The Effects of Complete Decongestive Therapy on Breast Cancer Related Lymphedema
Authors: Baltag O.M. , Singuran A.I. , Apostu M. , Cordun M.
Published: December 2023

Breast cancer-related lymphedema is the most common side effect that occurs after the treatment. There are four stages of evolution of the lymphedema and the most frequent treatment used is complete decongestive therapy (CDT). This study aims to analyze the effectiveness of CDT in the treatment of breast cancer-related lymphedema. After the final assessment, the data were processed statistically and we found that the evaluated circumferences decreased, which demonstrated the effectiveness of the CDT.
Physiotherapy in Postoperative Recovery through Total Arthroplasty of Secondary Coxarthrosis
Authors: Cioroiu Silviu Gabriel
Published: December 2023

Total hip arthroplasty is a surgical intervention that replaces the affected joint with an artificial implant. This is recommended in case of damage to the targeted joint and the installation of acute pain. Currently, the procedure is most commonly performed in orthopedics, although results and patient satisfaction in the short or long term vary widely The purpose of the research is to restore the movement capacity of the lower limb following the operation through good documentation of the condition and the postoperative effects on the functioning mechanism at the articular level and by finding the kinetotherapeutic methods and means that correspond to an effective recovery.
Post-Operative Recovery of Lumbar Disc Herniation
Authors: Nechita Florentina
Published: December 2023

Lumbar disc herniation is a common problem among people, especially those who are professionally active. The research emphasizes how to relieve lumbar pain, pain is the central symptom of disc herniation, and this can be solved by toning the hypotonic muscles. This will contribute to improving the functionality of the spine and even overcoming the patient's fear of movement after the operation. Thus, kinetic treatment methods and means will be applied to facilitate movements, reduce pain, and reintegrate the patient into professional activity.
Recording Progress in Junior Athletes' Proprioceptive Training using Modern Sports Technology
Authors: Alecu Stefan
Published: December 2023

This study investigates the efficacy of modern sports technology in monitoring and enhancing proprioceptive training among junior athletes. The research focuses on recording and analyzing the progress of young athletes engaged in proprioceptive exercises using state-of-the-art technological tools. Through a comprehensive examination of these advancements, this study aims to explore the impact of such technology on improving proprioception in junior athletes. The methods involve implementing specific training protocols while utilizing advanced tracking devices and analytical software to monitor and record the athletes' progress. The findings aim to provide insights into the effectiveness of modern sports technology in optimizing proprioceptive training among young athletes, thereby contributing to the enhancement of their overall athletic performance and injury prevention strategies.
The Importance of the Speed Execution in the Technical Procedures Specific to the Style Ashihara Karate
Authors: Mocioaca D. , Dragomir M.
Published: December 2023

This article brings to the attention of specialists in the field, considerations regarding the determining character of the execution speed in the technical procedures that are specific to the training of Ashihara Karate practitioners. The purpose of the research is to determine the influence that the development of execution speed has on technical training, and implicitly on sports performance. The experimental research took place over 8 weeks, including 15 athletes, and members of the Sen Craiova Sports Club, aged between 20 and 35. Following the analysis of the results, we emphasize the importance of improving the execution speed of specific training techniques in obtaining an optimal competitive performance.
APLIKASI REKAM MEDIS IMRAN MEDICAL CENTER MENGGUNAKAN REACT JS DENGAN METODE PROTOTYPE
Authors: Maolana Yusuf , Asriyanik  , Pambudi Agung
Published: December 2023

Imran Medical Center, sebagai penyedia layanan kesehatan, tengah berupaya mengatasi tantangan manajemen data rekam medis secara manual melalui pengembangan aplikasi digital. Aplikasi ini bertujuan mempermudah manajemen data pasien, riwayat pemeriksaan, dan pendaftaran pengobatan, menggantikan metode kertas yang saat ini digunakan. Dalam proses pengembangannya, Imran Medical Center mengadopsi metode Software Development Life Cycle (SDLC) Prototype, dengan JavaScript dan perpustakaan ReactJS sebagai bahasa pemrograman. Database disimpan melalui Hasura GraphQL. Kebutuhan aplikasi dikumpulkan melalui observasi, wawancara, dan studi literatur. Aplikasi ini diharapkan memberikan solusi efektif terhadap masalah pencarian data yang sulit, kehilangan data bulanan, dan ketidakefektifan dalam manajemen data. Dengan transformasi ke bentuk digital, hasil akhirnya berupa situs web yang tidak hanya mengatasi kendala tersebut tetapi juga menyediakan alternatif praktis dan efisien dalam manajemen rekam medis, meningkatkan kualitas pelayanan di Imran Medical Center.
PERENCANAAN APLIKASI PENDAFTARAN PESERTA PELATIHAN BERBASIS WEB DI BAPELKES PROVINSI JAMBI
Authors: Retiawan Frendi , Ramadhani Yerix , Najamuddin Muhammad Ariq , Amelia Mesy , Imron Al , Lesmana Dimas
Published: December 2023

Pesatnya perkembangan komputer dan teknologi informasi menjadi pemicu berbagai perusahaan seperti BAPELKES (Balai Pelatihan Kesehatan) provinsi Jambi untuk memanfaatkan sistem informasi baik berbasis desktop maupun Web. Permasalahan yang dihadapi dalam proses kegiatan pelatihan yaitu informasi pendaftaran bagi peserta terkendala jarak dan waktu, akurasi rekapitulasi hasil pelatihan, dan minimnya data saat penyusunan laporan hasil pelatihan secara periodik. Oleh karena itu, BAPELKES membutuhkan sebuah sistem informasi agar mendapatkan peluang bersaing dan meningkatkan eksistensi perusahaan. Metodologi yang digunakan adalah RUP (Rational Unified Process) dengan metode iterasi. Implementasi desain program menggunakan bahasa PHP (Personal Home Page) menggunakan MySQL. Dengan adanya sistem informasi administrasi berbasis web ini diharapkan dapat memberikan kemudahan dan meminimalisir kesalahan yang terjadi bagian administrasi maupun stakeholder yang terlibat langsung dalam kegiatan pelatihan tersebut.
PERANAN TENAGA ADMINISTRASI DALAM PENGELOLAAN ARSIP DI SMA YPKM MANADO
Authors: Mandulangi Jufrina , Tuwaidan Altje Ellen , Taju Donny , Rumerung Jeaneta J
Published: December 2023

Arsip merupakan salah satu sumber informasi penting yang dapat menunjang perubahan situasi dan kondisi yang berkembang dengan cepat. Didalam suatu organisasi sekolah sebagai lembaga pendidikan, informasi menjadi suatu hal yang sangat penting untuk mendukung kegiatan sekolah dalam menghadapi perubahan dengan cepat. Dalam Undang-Undang Republik Indonesia Nomor 43 Tahun 2009 tentang Kearsipan, pengelolaan arsip dilakukan untuk menjamin ketersediaan arsip yang benar, pelayanan arsip secara cepat, peruntukan penggunaan yang tepat, penyajian informasi yang dapat disajikan secara lengkap, dan adanya bukti pertanggung jawaban yang jelas.Pengelolaan arsip sekolah yang tepat akan menciptakan administrasi sekolah yang benar, sehingga dapat menjamin keselamatan dan keamanan administrasi guna menunjang produktivitas bagi sekolah. Arsip mempunyai peranan yang sangat penting bagi sekolah.Tenaga administrasi merupakan elemen yang harus diperhatikan oleh setiap organisasi sekolah karena sangat berhubungan langsung dengan pengelolaan arsip sekolah. Tenaga administrasi yang berada disekolah sangat membantu dalam pengelolaan arsip sekolah. Kurangnya pengelolaan arsip dari para tenaga administrasi dapat mengakibatkan penemuan kembali arsip sangat sulit dilakukan secara cepat dan bertambahnya arsip seiring dengan aktivitas suatu lembaga yang tidak diikuti dengan penyimpanan yang sistematis akan berakibat pada penumpukan arsip. Dalam observasi awal peneliti menemui masalah penataan arsip sekolah yang masih belum teratur, cara pengelolaan arsip yang masih kurang efektif, peranan tenaga administrasi yang belum teliti. Adapun yang menjadi tujuan adalah untuk mengetahui penataan arsip, pengelolaan arsip serta peran tenaga administrasi dalam mengelola arsip di SMA YPKM Manado. Jenis penelitian yang digunakan adalah metode kualitatif dengan pengumpulan data melalui observasi, wawancara dan dokumentasi.
A Effect of Pregnancy Spacing and Gravida on The Incidence of Miscarriage
Authors: Sofia Norlaila , Prihatanti Nur Rochmah , Megawati Megawati
Published: December 2023

Berdasarkan kajian determinan kematian ibu oleh Balitbang Kemenkes RI pada tahun 2012 bahwa 4,1% kematian ibu di Indonesia terjadi karena abortus. Faktor risiko terjadinya abortus yaitu faktor janin, maternal dan eksternal. Walaupun hanya berkontribusi 15% terhadap kejadian abortus, faktor maternal penting untuk diperhatikan khususnya dalam upaya pencegahan kejadian abortus. Salah satu penyumbang kasus abortus yang cukup tinggi di Kalimantan Selatan adalah Kabupaten Banjar. Tujuan penelitian yaitu menganalisis pengaruh faktor maternal jarak kehamilan dan gravida terhadap kejadian abortus. Rancangan penelitian ini observasional analitik dengan desain kasus kontrol. Kelompok kasus adalah semua ibu hamil yang mengalami abortus sebanyak 61 responden dan kelompok kontrol berjumlah 244 responden (1:4), penelitian dilaksanakan di wilayah kerja Puskesmas Astambul Kabupaten Banjar, Kalimantan Selatan pada tahun 2022. Data yang dikumpulkan adalah data sekunder, data dianalisis menggunakan uji chi square. Nilai P<0,05 dianggap bermakna secara statistik. Hasil penelitian menyatakan bahwa jarak kehamilan dan gravida tidak berpengaruh signifikan terhadap kejadian abortus (P>a), jarak kehamilan P = 0.405 dan gravida P = 0.341. Simpulan penelitian ini tidak terdapat pengaruh jarak kehamilan dan gravida terhadap kejadian abortus.

Kata Kunci: Abortus, Gravida, Jarak kehamilan
Działalność wojskowa Bernarda Pretwicza jako rotmistrza obrony potocznej
Authors: Łopatecki Karol , Stulgis Magdalena
Published: December 2023

The aim of this article is to present certain aspects concerning the functioning of the „Common Defense” system under the command of Bernard Pretwicz. The paper will compare two types of sources, i.e. written correspondence and taxation documents. This approach will allow the issue to be viewed in a broader context and provides the opportunity to piece together and also verify certain information. The following threads were traced: Bernard Pretwicz’s correspondence activity, his career and length of service, the size of his commands and his moneymaking activity.
Wojsko Polskie w kampanii wyborczej i wyborach do Sejmu PRL I kadencji z 26 października 1952 roku
Authors: Zaćmiński Andrzej
Published: December 2023

This article describes the role played by the Polish Army, as well as units of the Internal Security Corps, during certain stages of the election campaign and subsequent election of the first Sejm of the Polish People’s Republic held on 26 October 1952. Based on archival materials the paper highlights when and what organs of the Polish Army were involved in the election campaign. Aspects such as the process behind the organizing of the election, the propaganda and agitation campaigns that were conducted, and the electoral mood in the army are also discussed.
Chirurg Wielkiej Armii – Pierre François Percy (1754–1825) i jego wkład w rozwój medycyny wojskowej
Authors: Turos Maria
Published: December 2023

This article presents a biography of Pierre François Percy, who along with Dominique Jean Larrey and René Desgenettes was considered to be one of the most outstanding doctors from the Napoleonic Wars. Percy, who devoted a lot of space to Poland and Poles in his memoirs, served as the surgeon-in-chief of the Grand Armée during the Napoleonic campaigns. The text discusses his scientific achievements, especially in relation to emergency medical aid and the training of military surgeons.
Pctx1 venom in the treatment of vasospasm due to experimental subarachnoidal hemorrhage
Authors: AKGÜN Mehmet Yigit , AKGÜL Mehmet Hüseyin
Published: December 2023

Aims: We aimed to investigate the role of neuron damage in experimental animals following vasospasm, by increasing perfusion of neuronal tissue through vasodilation using the venom of PcTx1, and to determine its effectiveness in reducing neuron damage after vasospasm.

Methods: Thirty adult male Wistar albino rats weighing between 300 and 400 grams were used and divided into three groups: the Sham group (Group 1, n=10), to which no application was made; the SAH (control) group (Group 2, n=10), in which a double SAH model was created and 1 cc of saline was administered intraperitoneally; and the SAH+PcTx1 group (Group 3, n=10), in which a double SAH model was created and 1 cc/kg of PcTx1 venom was administered intraperitoneally daily. Basilar artery diameter and immunochemical measurements were performed histopathologically, and neurohistopathological findings were scored semiquantitatively in terms of vascular changes, neuron degeneration, gliosis, and bleeding criteria using a scale of 0 (none), 1 (mild), 2 (moderate), or 3 (severe). eNOS immunopositivity was also evaluated. The detection of apoptosis in the brain was performed by evaluating the effector enzyme caspase-3 immunoreactivity of the exogenous apoptosis pathway.

Results: The most severe vascular spasm and degeneration-necrosis of brain tissue gray matter neurons were seen in Group 2, whereas the vascular narrowing was less severe in Group 3. Brain parenchyma and neuron and neuroglial reactions were milder in Group 3. eNOS expression was detected at a higher level in Group 1, Group 2, and Group 3, respectively. For apoptosis and caspase-3 immunoreactivity of the exogenous apoptosis pathway, no immunopositive reactions were observed in Group 1.

Conclusion: For the occurrence and formation mechanisms of vasospasm after subarachnoid hemorrhage, this pathological condition is thought to result from multifactorial and various biochemical reactions. In our study, it was found that psalmotoxin effectively prevented vasospasm and significantly reduced tissue damage after vasospasm.
The value of albumin-related ratios in predicting disease severity and mortality in acute cholangitis
Authors: YEŞİL Bayram , SEVİM Bünyamin
Published: December 2023

Aims: Acute cholangitis is a potentially fatal bacterial illness that poses a significant risk to patients if not promptly addressed, despite the progress made in the field of diagnosis and treatment. Multiple laboratory and clinical data are employed in assessing the severity and fatality rates associated with acute cholangitis. This study aimed to assess the predictive utility of the ratio between elevated laboratory results and albumin levels in determining the severity of disease and mortality rates in patients with cholangitis.

Methods: The study comprised a cohort of 471 individuals diagnosed with acute cholangitis, alongside a control group of 150 individuals without acute cholangitis. The patients' information was acquired by conducting a retrospective search of the computerized database. The study collected data on the age, gender, routine laboratory parameters, concomitant disorders, etiology of cholangitis, and outcomes (discharge or death) of all patients. The patients were categorized into three grades, namely grade 1, grade 2, and grade 3, based on the severity of cholangitis, using the Tokyo 2018 standards as a reference.

Results: The study comprised a sample size of 621 people. Out of the whole sample size, 53.1% (330 individuals) were identified as male. The study observed a broad range of ages (23-98) with a median age of 67 years, which was found to be greater in the cholangitis group. Among the patients in the cholangitis group, a mortality rate of 6.8% (32 individuals) was observed. A notable disparity was seen in all laboratory parameters between the two groups. The cholangitis group had greater levels of albumin-related ratios, and there was a positive correlation observed between all ratios and the severity of the condition. In deceased individuals, there were greater rates observed for variables other than the γ-glutamyl transferase/albumin ratio (GAR). The results of both univariate and multivariate regression analyses demonstrated a significant correlation between the ratios of direct bilirubin to albumin (DBAR), international normalized ratio to albumin (IAR), neutrophil to albumin (NAR), and mortality. Additionally, the study revealed that the mortality and severity of cholangitis could be predicted by all the albumin-related ratios examined, particularly the INR/albumin ratio (IAR), as indicated by the ROC analysis.

Conclusion: It is posited that the utilization of albumin-related ratios, obtainable through routine laboratory testing, may serve as an effective means to assess the severity of acute cholangitis and predict mortality rates associated with the condition. Immediate biliary drainage is recommended for patients with elevated ratios.
Distribution of bacteria isolated from urine cultures and resistance pattern of Escherichia coli strains in community-acquired urinary tract infections
Authors: BULUT Dilek , KARAKOÇ Hanife Nur
Published: December 2023

Aims: Urinary tract infections are one of the most common among community-acquired infections. Escherichia coli (E. coli) is the most common cause of community-acquired urinary tract infections. In our study, we aimed to determine the correct empirical treatment by determining the resistance profile of E. coli strains isolated from urine cultures in our hospital, thus both establishing an effective treatment and preventing the development of resistance.

Methods: Urine cultures of 3145 patients with urinary tract infection symptoms who applied to the infection and clinical microbiology outpatient clinic of our hospital between January 2019 and December 2019 were analyzed retrospectively. Patients with a history of catheter, a history of urinary operations, a history of hospitalization in the last 15 days, contamination in their cultures, and patients under the age of 18 were excluded from the study, and 422 urine cultures with growth were included in the study.

Results: The mean age of the patients included in the study was 49.8±14.7 years, and the gender distribution consisted of 301 females (71.3%) and 121 males (28.7%). E. coli was isolated in 313 (77.6%) of these cultures. The antibiotic with the highest resistance rate was trimethoprim-sulfametoxazole (34.8%), while the antibiotics with the lowest resistance rates were fosfomycin and imipenem (0.6%).

Conclusions: Considering that the resistance profiles of microorganisms are different from each other on the basis of country, region, and city, revealing regional resistance patterns can make an important contribution to both establishing effective treatment and preventing the development of antibiotic resistance.
Reappraisal of the role of Helicobacter pylori in chronic spontaneous urticaria
Authors: ÖRNEK ÖZDEMİR Sinem , ÖZGÜR Emek
Published: December 2023

Aims: Chronic spontaneous urticaria (CSU) is one of the most prevalent skin disorders. Helicobacter pylori (HP) infection has been linked to CSU, and HP eradication therapy has been questioned as a viable treatment option. However, studies have produced contradictory results. In addition, recent studies suggest that gastritis, rather than HP bacteria, may be responsible for CSU symptoms. Herein, we aimed to ascertain the prevalence of HP infection in CSU, explore associations between HP infection, gastritis, and CSU severity or treatment response in CSU, and investigate the impact of HP eradication therapy on the CSU course.

Methods: We retrospectively analyzed CSU patients who were investigated for HP infection. Patient characteristics, in-clinic urticaria activity scores (ic-UAS) and urticaria control test (UCT) scores, and CSU treatment responses were compared across different patient groups.

Results: The study included 325 CSU patients, of whom 57.2% were HP-positive and 60.9% had gastritis. The mean baseline ic-UAS showed no difference between HP-positive and HP-negative patients (2.55±2 vs 2.45±1.98, p>0.05) or between patients with and without gastritis (2.33±2 vs 2.51±2, p>0.05). HP-positive patients had higher rates of elevated CRP levels (45% vs 29.9%, p=0.023) and ASST positivity (54.8% vs 29.8%, p0.05).

Conclusion: Over half of CSU patients have been found to be infected with HP. However, the HP bacterium itself, the eradication of HP, or gastritis have no significant effect on CSU severity or treatment response.
Pediatric forearm fractures: evaluating implant removal timing and complications with exposed titanium-elastic nail tips
Authors: GÖLGELİOĞLU Fatih , YALIN Mustafa
Published: December 2023

Aims: The current study investigates complication rates, timing of implant removal, and correlations between removal timing and complications/refractures in pediatric forearm fracture patients who had exposed titanium-elastic nail (TEN) tips.

Methods: This retrospective single-center study analyzed pediatric forearm fractures in patients who underwent TEN with exposed tips. Inclusion criteria covered cases between August 2018 and January 2022, focusing on children with both-bone forearm fractures and unsuccessful conservative treatment. Data included demographics, fracture details, reduction type, implant removal timing, complications, and refracture rates.

Results: Between August 2018 and August 2022, the study involved 65 children (54 boys, 11 girls), aged 4 to 15 years. Implant removal occurred at 4 to 11 weeks, on average at 7.17±1.52 weeks. Fracture location was distal 1/3 (9.2%), middle 1/3 (78.5%), proximal 1/3 (12.3%). The predominant causes of fractures were falls (89.2%). Fracture types consisted of open fractures (6.2%) and closed fractures (93.8%). Reduction methods included mini-open reduction (9.2%) and closed reduction (90.8%). Implant removal occurred at or before 6 weeks for 43.1% of cases, while it exceeded 6 weeks for 56.9% of cases. Complications were noted in 21.5% of cases, encompassing delayed union (14.3%), hypertrophic granuloma (7.1%), infection (21.4%), skin irritation (42.9%), and refracture (14.3%). Clinical outcomes were classified as excellent in 83.1% of cases and good in 16.9% of cases. No statistically significant differences were observed in complications (p=0.351) or clinical outcomes (p=0.441) based on implant removal timing.

Conclusion: Contrary to belief, exposing nail tips, not burying them, is safe, cost-effective, and leads to minimal complications with positive clinical outcomes. Implant removal timing did not significantly impact clinical outcomes or complications. TENs used in forearm fractures can be removed before 6 weeks when adequate union is observed.
Exploring occupational safety and health in future workscapes
Authors: AKYILDIZ Cengiz
Published: December 2023

Aims: The aim of this manuscript is to address the evolving dynamics of work, which are placing increasing demands on current occupational safety and health (OSH) protocols. It emphasizes the need for a more adaptable approach to ensure safe and efficient work environments. The primary objective is to introduce new frameworks capable of handling the uncertainties of the future in OSH.

Methods: To tackle the challenges posed by the changing landscape of work, the U.S. National Institute for Occupational Safety and Health (NIOSH) has adopted a strategic foresight approach. This approach is rooted in future studies and strategic planning, allowing NIOSH to anticipate future challenges in OSH. It involves creating well-structured and informed scenarios of potential futures, enabling organizations to prepare effectively for upcoming challenges and capitalize on emerging opportunities.

Results: This manuscript represents NIOSH's inaugural foray into strategic foresight. The results showcase the integration of strategic foresight methods to enhance institutional readiness in the realm of OSH. The study delves deep into the anticipated trajectories of OSH research and protocols, offering valuable insights into the future of OSH.

Conclusion: In conclusion, the evolving nature of work necessitates a more adaptable approach to occupational safety and health. NIOSH's strategic foresight venture marks a significant step towards achieving this goal. By proactively preparing for future challenges and opportunities, organizations can ensure safer and more efficient work environments. This manuscript provides a foundation for enhancing institutional readiness and navigating the evolving landscape of OSH research and protocols.
Komunikasi Efektif dalam Moderasi Beragama Melalui Film Dokumenter “Selaras”
Authors: Marini Marini Marini , Salas Hugo Julio , Kadri Wahab Nur
Published: December 2023

Religious moderation exists as an adhesive for similarities, not for sharpening differences. Many religious conflicts occur, such as rejection of the construction of places of worship, rejection of certain religious communities, hatred, hatred, hatred of places of worship, lack of peace in worship and many others. Therefore, effective communication facilities are needed to educate the public about the importance of implementing tolerance between religious communities so that life becomes harmonious. Diverse moderation is needed to be able to create peace in diversity. Therefore, the application of religious moderation in Indonesia is very necessary as a cultural strategy. There are many media that can be used, one of which is documentary films. This is also reflected in the documentary film “Selaras” which carries the theme of moderating the various people of Pekon Ambarawa Pringsewu. This research uses a qualitative approach with descriptive methods. The paradigm in this research is constructivism. The theory used in this study is the Tubbs and Moss model of effective communication theory. The results of this study it can be concluded that in the documentary "Selaras" there are various indicators of moderation.