bluuebunny/crossref_metadata_2025 huggingface dataset:
Elucidating the Effects of Symmetry and Glycemic Conditions on Dermal Wound Healing Using a Novel Laser Direct Write Photoablation Assay
Authors: Saksena Jayant , Penrose Harrison M , Burow Matthew E. , Chrisey Douglas B.
Published: June 2023

Conventional wound healing assays are inadequate for evaluating the influence of symmetry on wound healing as they either offer poor geometrical control of the wounds created or fail to trigger a wound healing response in cell layers. To address these issues, herein we developed a novel CAD/CAM laser direct write photoablation assay that enables the generation of wounds with precisely defined and highly customizable geometries. As proof of principle, we biologically validated this assay to study the influence of symmetry and glycemic condition on dermal wound healing. We demonstrated that dermal wounds with symmetrical geometries tend to heal faster than those with asymmetrical geometries regardless of the glycemic conditions. Further, we elucidated the relative strength of the effects of symmetry and glycemic condition on healing rates in the context of the dermal wound size.
A parasznyai Kő-lyuk I. új ásatásainak első eredményei
Authors: Szolyák Péter
Published: June 2023

Az őskőkorkutatás magyarországi történetét az első évtizedekben leginkább a barlangok ásatásai határozták meg. A második világháborút követően megritkultak az ilyen típusú régészeti-őslénytani feltárások. Mivel addig rendkívül intenzíven zajlott a kutatás, az új generációk számára, a barlangok felső rétegeinek és sokszor a dokumentációk kisebb-nagyobb részének hiánya miatt, kifejezetten nehéz feladat lett "újraolvasni" az egyes lelőhelyek történetének indító fejezeteit. A Bükk hegység északi részén, Parasznya határában található Kőlyuk I. kiváló és talán az egyik utolsó lehetőség arra, hogy a legnagyobb ősemberbarlangjainkhoz mérhető üregben napjaink taposási felszínétől kezdjük el aprólékosan visszafejteni az időt.
Egy edénytől a közösségig : Egy különleges bronzkori edénytípus funkciójának vizsgálati lehetőségei
Authors: Szabó Nóra
Published: June 2023

Jelen tanulmány középpontjában a pácolóedények felhasználásának, valamint a középső bronzkori közösségekben betöltött szerepének rekonstruálási kísérlete áll. Az edénytípus a bronzkor több periódusában is fellelhető, azonban használata a középső bronzkorban (2000/1900–1500/1400 cal BC) tűnik a legelterjedtebbnek. A belső bütykökkel és különleges díszítéssel ellátott tárolóedényeket korábban tejtermékek készítésével vagy alkoholos italok erjesztésével hozták összefüggésbe, azonban egyértelmű válaszokat pusztán formai és néprajzi párhuzamok alapján nem kaphatunk. Az eddig kis példányszámban ismert, de sok esetben különleges összefüggésben, úgynevezett strukturált depozitumok részeként előforduló edénytípus valós funkciójának ismerete számos új információval szolgálhat az i. e. 2. évezred első felének étkezési szokásairól és azok társadalmi összefüggéseiről.
Okkupáció – transzformáció – kommunikáció: A földrajzi környezet, a területi közigazgatás és közlekedés kölcsönhatása az Észak-Dunántúlon a római korban : Az ALP-projekt
Authors: Bödőcs András
Published: June 2023

Amikor a Római Birodalom terjeszkedő politikája elérte a mai Dunántúl területét és Pannonia tartományként a birodalom részévé tette, a Kárpát-medence ezen része először került erős központi hatalom irányítása alá. A korábban itt létrejött gazdasági és társadalmi keretek nem csak e terület történelmét határozták meg több évszázadra, hanem azok formáját is. Egyre jobban értjük már, hogyan is szerveződött a gazdaság, a társadalom vagy egyszerűen csak az élet az egykori birodalom területén. Kutatási projektünk alapvetően az ún. „nem romboló” régészeti módszerek alkalmazásával, azaz jellemzően nem ásatásokkal szeretne elsősorban Pannonia, azon belül ÉNY-Dunántúl római kori be- és megtelepülésének folyamatára koncentrálni. Ki szeretnénk mutatni az új hatalmi helyzet és gazdasági szerkezet környezetre gyakorolt hatását, valamint rávilágítani a katonai megszállás mögött, lassú migrációs folyamatokkal érkező népesség és a helyi lakosság keveredésével létrejött új gazdasági egységek kialakulására. A fókusz most nem az állandó katonai jelenlétet kívánó határvidékre, a limesre, hanem a hátországot jelentő, a gazdasági termelést és a hadsereg ellátását biztosító belső területekre kerül.
Standarisasi Sarana dan Prasarana Laboratorium dalam Peningkatan Kompetensi Mahasiswa Pariwisata Budaya dan Keagamaan IAKN Tarutung
Authors: Lase Sudirman , Nadeak Tio R.J , Situmeang Diana Martiani , Fero David
Published: June 2023

This study uses qualitative methods to describe the research object or research results. This research was conducted at the Batak Museum T.B. Please Center. As for the consideration of the researchers in choosing the research location because the researchers saw that it was necessary to test the availability of facilities and infrastructure in the museum for analysis and could become input in the standardization of facilities and infrastructure for the practicum of the Cultural and Religious Tourism Study Program. From the results of the research, it was found that it is necessary to hold a cultural and religious tourism laboratory which refers to the standardization of facilities and infrastructure, which includes laboratory buildings, laboratory facilities, laboratory equipment, materials and laboratory management personnel which can be referred to according to what researchers found at the Batak Museum T.B. Please Center.
Targeted and Immunotherapy Approaches in HER2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma: A New Era
Authors: Radford Maluki , Abushukair Hassan , Hentzen Stijn , Cavalcante Ludimila , Saeed Anwaar
Published: June 2023

HER2-targeted therapy with the HER2 monoclonal antibody trastuzumab has achieved impressive outcomes in the first-line settings of patients with advanced gastric and gastroesophageal junction (GEJ) adenocarcinoma overexpressing HER2. However, considering that a substantial proportion of those patients eventually relapses, as well as the relatively limited performance of those agents in second-line settings, a deeper understanding of resistance mechanisms is needed for enhanced guidance for patients’ therapeutic selection in the second-line setting and beyond. In this review, we highlight trastuzumab’s (HER2-targeting agent) performance in patients with gastric or GEJ cancer, with insight into mechanisms of resistance. We also discuss the new integration of PD-1 inhibitor pembrolizumab into the trastuzumab for gastric cancer frontline regimen, the latest addition of trastuzumab deruxtecan to the treatment armamentarium, and the potential of pipeline HER2-targeting approaches and combinations in patients with gastric or GEJ adenocarcinoma.
Leishmaniose tegumentar americana: características epidemiológicas dos últimos 10 anos de notificação
Authors: Barbosa de Oliveira Rego José Rogério , Cavalcanti Manso Orlando Gonçalves Ferreira , Feitosa D'Almeida Filho Luciano , Pol-Fachin Laércio , Fontes Lima Ana Luísa Torres
Published: June 2023

Introdução: A Leishmaniose Tegumentar Americana (LTA) é uma doença parasitária transmitida pela picada do vetor infectado e representa um desafio para a saúde pública no Brasil. Este estudo visa traçar as características epidemiológicas mais relevantes da LTA no país nos últimos 10 anos. Objetivos: Descrever a distribuição da LTA no Brasil no período de 2013 a 2022, incluindo fatores como notificações, faixa etária, sexo, tipo de entrada e evolução do caso. A revisão dos dados tem o intuito de compreender a evolução da doença e embasar estratégias de prevenção e controle. Métodos: Trata-se de uma pesquisa epidemiológica descritiva, que utiliza dados obtidos do Sistema de Informação de Agravos de Notificação (SINAN) do SUS, além de bases de dados como PUBMED, SCIELO e Google Acadêmico. Os indicadores utilizados incluem o número total de notificações, localização geográfica, faixa etária, sexo, tipo de entrada e evolução do caso. Resultados: As notificações de LTA demonstraram prevalência pelos estados de PA, MT e BA, além da faixa etária entre os adultos jovens e do sexo masculino. Os achados positivos das notificações analisadas se dão pela alta porcentagem de evolução de cura da doença e pelo baixo índice de recidiva. Conclusão: A compreensão das características epidemiológicas da LTA no Brasil é fundamental para o direcionamento de estratégias eficientes de prevenção e controle. A revisão dos dados ressalta a necessidade de abordagens integradas, incluindo medidas de proteção individual, controle de vetores e a busca por uma vacina eficaz. A vigilância epidemiológica contínua é crucial para identificar mudanças no perfil da doença e embasar ações de saúde pública.
Interesses de estudantes gaúchos em Ciências da Natureza e suas relações com as Unidades Temáticas da BNCC
Authors: Da Rosa Poliana Antunes , De Tolentino-Neto Luiz Caldeira Brant
Published: June 2023

O presente estudo dedica-se a discorrer sobre as preferências dos estudantes dos Anos Finais do Ensino Fundamental com relação aos temas de interesses nas aulas de Ciências da Natureza. A investigação foi realizada em uma escola estadual da região central do Rio Grande do Sul, por meio de um questionamento aos educandos do 6º ao 9º ano sobre seus Objetos de Conhecimentos de preferência nas aulas do Componente Curricular. Ao serem interrogados sobre “Quais os temas despertam seu interesse nas aulas de Ciências”, os resultados foram agrupados dentro das Unidades Temáticas da Área de Conhecimento de Ciências da Natureza da BNCC, a saber: I) Matéria e Energia; II) Vida e Evolução e III) Terra e Universo.  Os resultados evidenciam a preferência pelos Objetos de Conhecimento da Unidade Temática Vida e Evolução, em detrimento das demais apresentadas pela Base Nacional Comum Curricular (BNCC). Os resultados vão ao encontro dos dados coletados em uma amostra estadual do questionário ROSES - Relevância da Educação em Ciências. A partir do conhecimento dos tópicos de maiores interesses dos estudantes, pode-se delinear caminhos para as políticas públicas e a atuação docente, principalmente para que despertem a participação ativa dos jovens nas aulas de Ciências e sua motivação para aprender.
ANALYSIS OF THE EXPERT ASSESSMENT FEATURES OF THE INNOVATIVE ACTIVITIES RISKS OF THE AGRICULTURAL ENTERPRISE
Authors: Surkova Viktoriia
Published: June 2023

At the current stage of society's development, during the period of the greatest scientific-technical and socio-economic transformations, the need to obtain reliable and substantiated information as a basis for making management decisions is growing. In most cases, the sources of such information are the most competent, that have in-depth knowledge of the subject of research, specialists-experts included in the problem. Surveys ensure obtaining data on the opinion, knowledge of people regarding certain innovations, identifying their quantitative parameters and prevalence. They reveal the reflection of this or that problem, but do not provide an understanding of the possible causes and ways of solving it. In addition, the assessments and self-assessments expressed by respondents in a mass survey can often be distorted. The tasks of the expert survey are focused on obtaining substantiated information on the studied problem, reflected in the opinions and assessments of specialists who have sufficient experience and knowledge in the field of solving complex problem tasks for the formulation of conclusions and practical recommendations. This allows providing management subjects with the information necessary for making and implementing management decisions regarding innovations, ensuring their objectivity, competence, comprehensiveness, and multilateralism. The main difference between an expert survey is due to the role of an expert, who acts not as an object of research, but as a participant, a kind of tool for evaluating the object under study. to make a cost-effective decision about implementing the project, abandoning it, or holding it until the situation in the environment or at the enterprise improves. The results of expert evaluations of innovation risk are the basis for the implementation of the next stage of management - the stage of regulation (response to innovation risk), based on the choice of methods of optimization of innovation risk.
Keywords: risk, innovation, evaluation, uncertainty, experts.
METHODS AND INDICATORS OF ASSESSING MANAGEMENT PERFORMANCE IN THE ORGANIZATION
Authors: Kravchyk Yurii , Ostapchuk Olha
Published: June 2023

At the current stage of society's development, during the greatest scientific-technical and socio-economic period. To be a successful organization for a long time, to survive and achieve its goal, the organization must be both efficient and effective. Performance management combines methodologies, indicators, processes, software, and systems for managing the organization's activities. The essence of performance management is to make the right decisions, the correctness of which will be confirmed and ultimately measured by the results of actions. Performance management increases the predictability of outcomes, clarifies the connections between strategic, operational, and financial goals, and makes them clear to managers and groups of employees, which allows them to act instead of waiting for instructions from superiors. Performance management allows quantifying the effectiveness of cost planning using key performance indicators derived from strategic maps and balanced scorecards. Knowing these strategic goals and their relative importance, managers and employee teams select appropriate tools from the entire performance management suite. It has been established that several different types of organizational results can be viewed and compared. It is emphasized that the assessment of management performance is a complex task and a necessary preliminary stage of improving the management system. Therefore there are many criteria for such an assessment that consider various factors affecting performance and allow a comprehensive evaluation of the company's implemented strategy. Effectiveness is not only a question of what is done but also how. Excellent results are made possible by appropriate behavior, especially voluntary behavior, and the effective application of the necessary knowledge, skills, and competencies. Performance management allows us to understand precisely how results are achieved, as it allows us to understand what activities are needed for the organization's further growth. Managers must be ready, willing, and able to identify and address improvement needs as soon as they arise. It is necessary to strive for the maximum possible integration of knowledge and professional practice. This means encouraging managers in every possible way to learn from successful examples, difficulties, and problems.
Keywords: productivity, assessment, management, organization, indicators.
THEORETICAL ASPECTS OF BRANDING FOR THE DEVELOPMENT OF BRAND MANAGEMENT STRATEGY AT UKRAINIAN ENTERPRISES
Authors: Blyznyuk Tetyana , Olga Maistrenko
Published: June 2023

The importance of the problem of forming and managing Ukrainian brands (trademarks) is determined by the fact that well-known brands become an important condition for a company's stable position on the market, and one of the key factors is its profitability and competitiveness. The world experience was considered and analyzed, which shows that at the current stage of development of competitive markets, brands are fighting for a place in the minds of buyers. The theoretical aspects of the justification of the brand and brand management were studied, and a holistic definition of the concept of "brand" was formed. In the article, the tools of brand management and its system are formed, agreed, and characterized. The sequence of use and formation of the brand, its stages are highlighted. Based on the conducted research, the expenses for the formation and implementation of the brand in the sales and service personnel of the Ukrainian company were compiled. All this makes the analysis of practical experience and the development of a theoretical concept of brand management of trade and production of Ukrainian companies relevant in the conditions of modern realities. The criteria determining the priority of brand effectiveness of sales and service personnel of Ukrainian companies are compared. The possibility of practical use of its results in the activities of Ukrainian companies makes this work particularly relevant. A SWOT analysis of the company's activities was carried out, which identified the company's strengths and weaknesses, potential advantages, and threats that the company may face in its activities. It has been proven that the formation and development of a brand in the sales and service personnel of a Ukrainian company from the field of commerce is economically beneficial. The proposed elements of the brand will help the enterprise to increase its economic efficiency, which is necessary in the current economic situation in the country, as well as in the financial state of the enterprise.
Keywords: brand, brand management, branding, brand effectiveness, brand tools.
The system of personnel training in the field of creating an accessible environment for the disabled and other people with limited mobility
Authors: Vladimirova Oksana N. , Ivashkina Julia J. , Kovalev Vitaluj A. , Matveeva Marina V.
Published: June 2023

The relevance of this article is due to the increased need for the training of highly qualified personnel on the issues of the accessible environment. The purpose of the article is to conduct a study among educational institutions of higher secondary vocational and additional vocational education and to identify the presence in the programs of the presence of components fully or partially devoted to issues of an accessible environment, for a wide range of groups of professions, specialties and areas of training. The authors formulated the main objectives of the study and prepared a range of questions related to the topic of the accessible environment. Based on the results of the study, general conclusions were made and specific areas of work were identified to organize systematic training of personnel on issues of the accessible environment. Moreover, upon completion of a detailed analysis of the survey, proposals are being presented on the development of the state system for training and advanced training of managers and specialists in the field of providing an accessible environment for people with disabilities.
The foreign language virtual lecture as an instrument of professional-competency formation in foreign-language teacher training institutions
Authors: Ibragimova Liliya A. , Sarapulova Alexandra E.
Published: June 2023

Modern information and communication technologies provide many opportunities for the use of authentic foreign-language materials in the educational process in foreign-language teacher training institutions. Of particular interest in this regard are virtual lectures on topics directly related to this professional field. Nevertheless, the problem of using foreign-language virtual lectures in university classes has not been sufficiently covered in the scientific literature, as a result of which this tool is not widely used. This study aims to reveal the potential of using professionally oriented foreign-language virtual lectures to enhance the professional competencies of future foreign-language teachers during their university training. The main focus lies on the listening competency as an inherent part of the foreign-language teachers communicative capacities. The potential of using virtual lectures for formation of other competencies is also discussed in the context of an integrative approach. This issue is of particular relevance since the integrative approach becomes more and more popular in the higher education system. The research is based on the authors examination of the relevant scientific literature and on her analysis of a number of English-language virtual lectures dealing with pedagogy and foreign-language teaching methods. These steps allowed to highlight the main features of virtual lectures as teaching material and to describe various types of classroom tasks designed to accompany them. Moreover, the author presents a brief overview of digital sources where foreign-language virtual lectures are available. She also enumerates the professional competencies that c an be enhanced integratively by the use of foreign-language virtual lectures and the learning tasks associated with them. The results of the study demonstrate that professionally oriented foreign-language virtual lectures have great potential as a tool for the integrated formation of listening and other professional competencies of foreign-language teachers. However, for the educational process to be effective, the teacher also needs to engage in some additional work of a methodological nature. Thus, creating a solid theoretical and methodological ground for the use of virtual lectures in the classroom becomes an urgent problem, which may open up a path towards further research in this area.
Professional orientation of students of pedagogical universities: problem statement
Authors: Kandaurova Anna V.
Published: June 2023

In the modern educational space of all regions of the Russia Federation, there is, firstly, a shortage of teaching staff, secondly, the short period of work of young teachers at school, and thirdly, a decrease in interest in the teaching profession among applicants. Managers of all levels from school to federal, scientists, politicians are thinking about alarming statistics. In search of a solution to this problem, an attempt has been made to scientifically comprehend the phenomenon of professional and pedagogical orientation as a personal quality that determines successful professional activity. The purpose of this publication is to actualize the problem of professional and pedagogical orientation among students of pedagogical universities, namely: clarifying the content of this concept, identifying the main psychological mechanisms, determinants, factors and conditions for the formation and development of this personal quality. The paper also attempts to empirically prove the dynamics of the development of professional and pedagogical orientation among students of the pedagogical University and the search for possible pedagogical conditions and means for managing and purposefully influencing the development of this quality during the period of students' education. Both qualitative and quantitative methods were used in the study: content analysis of informational and journalistic materials; qualitative and semantic analysis of essays; testing, questionnaire, survey, conversation. The results obtained confirm the fears of politicians and education managers: not all graduates really plan to devote their lives to the profession of a teacher after graduation. Moreover, the results obtained confirm the dynamic nature of the professional and pedagogical orientation; its determination depends on the variability of the motives of professional choice, the image of the profession, personal experience. The article offers the main pedagogical conditions and means for the development of professional and pedagogical orientation of students, the analysis and development of which can become the tasks of further research.
Transdisciplinarity / cross-disciplinarity / multidisciplinarity in language teaching projects for future translators
Authors: Plastinina Nina A. , Stepanova Marina A. , Bogdanova Svetlana Y.
Published: June 2023

The article discusses the role of transdisciplinary, cross-disciplinary, multidisciplinary approach in translators' training. The paper provides an overview of this cluster of terms, underlining, on the one hand, their problematic ambiguity and, on the other, their conceptual similarity a better match either between a professional environment and academia or borrowing from (lending to) the knowledge and skills from different disciplines to solve a problem. The paper dwells on the educational potential of transdisciplinary education and the direction it has taken in recent decades. The authors claim the academic translator training can benefit from a suchlike approach. The transdisciplinary / cross-disciplinary project is outlined as the way by which a better practice-oriented and practice-based cumulative knowledge and learning can be formed. Specifically, the paper focuses on some academic translator projects aimed at students' dealing with audiovisual translation of video, infographics and multimedia resources for academic purposes and international events support. The paper illustrates how these projects can be implemented. The authors have stepped up their efforts towards including more transdisciplinary / cross-disciplinary / multidisciplinary projects in their curricula to show how the constructive correlations between educational and professional environment can be built providing more practice-focused knowledge and skills integration for students.
Forecasting area, productivity and prices of mango in Valsad District of Gujarat: Time series analysis
Authors: Garde Yogesh , Chavda R. R. , Thorat V. S. , Pisal R. R. , Shrivastava Alok , Varshney Nitin
Published: June 2023

Mango on an average account approximately 75 per cent of total production quantity.  India is the largest mango producer, accounting for about half of the world-wide mango production. Forecasting of area, production and price fluctuations are the key to provide support in decision making and proper planning for sustainable growth of farmers and other people who are dependent on horticulture. The prices of mango are affected by cultivated area and yield of mango but in other ways pre or post-harvest management also affects it. The problems regarding the price fluctuations arise due to seasonality in arrival and its perishable nature. Therefore, the present study was carried out with time series intervention modelling in forecasting area, productivity and prices of mangoes. In the current investigation, simple exponential smoothing (SES) implemented to develop the forecasting models for area and productivity of mango. Under the SES, the error measurements at different values of alpha (a) for forecasting of area and productivity were observed that the value 0.8 and 0.9 of alpha (a) showed minimum Mean Absolute Percentage Error (MAPE) error i.e. 3.11 per cent, and 12.73 per cent, respectively. The study also developed time series ARIMA models for forecasting the prices of the mango (Keshar and Alphonso) for Valsad markets of Gujarat. It was showed that ARIMA (6, 1, 2) and ARIMA (1, 1, 2) were found good models for forecasting the prices of the Keshar and Alphonso, respectively in Valsad district of Gujarat
Effect of zinc and silicon nanoparticles on yield, quality and economics of lowland paddy
Authors: Karchedu Soumya , Gubbi Koteodayar Girijesh , Salimath Sarvajna Basavarajayya , Hanchinmani Veeranna , Marulasiddappa Dushyanthkumar Banur
Published: June 2023

An investigation to know the effect of nano zinc and silicon on quality and yield of rice was conducted at AHRS, Bavikere, KSNUAHS, Shivamogga. The experiment consisted 12 treatments replicated thrice and was laid in completely randomized block design. The different treatment combinations of seed treatment of nano zinc and silicon, foliar spray of zinc and silicon nanoparticles were compared with conventional sources and the control. Application of both zinc and silicon (T6) in nano form as foliar @ 40 ppm each at 40 DAT registered significantly higher no. of productive tillers (18.72), protein content (11.41 %), starch content (75.70 %) grain yield (6034 kg/ha), straw yield (6693 kg/ha) with higher economic net returns (98631 Rs ha-1), foliar spray of zinc nano particles alone @ 40 ppm at 40 DAT showed next best results.
Genetic variability studies in field pea (Pisum sativum L.) for yield and associated characters
Authors: Jagadeesh Kommineni , Mahto Chandra Shekar , Kumar Niraj
Published: June 2023

The prime and foremost objective of the study was to estimate the genetic variability for yield and its associated characteristics among the 23 genotypes of field pea and also to engender information regarding genetic parameters like range, mean, phenotypic coefficient of variation (PCV), genotypic coefficient of variation (GCV), heritability and genetic advance as a percentage over means for the18 traits under consideration. It was disclosed from the results of the analysis of variance that there exists a difference among the 23 genotypes for all the 18 traits under consideration. The trait including primary branches per plant, secondary branches per plant, plant height, swelling capacity, swelling index, biological yield per plant, and seed yield recorded high amounts of GCV and PCV. High heritability combined with high genetic advance was documented for the trait’s plant height and seeds per plant, whereas high heritability coupled with low genetic advance, was recorded for the trait’s days to fifty % flowering, days to maturity, primary branches per plant, secondary branches per plant, pod length, 100 seed weight, percent disease incidence and seed yield per plant. The existing variability identified can be further exploited in crop improvement of field pea
Variability and correlation studies in bacterial wilt resistant advanced tomato lines (Solanum lycopersicum L.)
Authors: Sadat Sayed Hasibullah , Chadha Sanjay , Sharma Shaina
Published: June 2023

Twenty bacterial wilt resistant lines including recently developed lines at CSKHPKV, Palampur (08) were studied to ascertain the extent of genetic variability, the type and magnitude of correlation between component characters & marketable yield, as well as the direct and indirect impacts of every character on marketable yield. For all variables except plant survival, analysis of variance exhibited significant differences across genotypes. Phenotypic coefficient of variation (PCV) and genotypic coefficient of variation (GCV) values for lycopene content (80.581%, 80.148%), titrable acidity (73.666%, 71.219%), marketable yield / plant (53.953%, 52.598%), marketable fruits / plant (34.994%, 34.050%), gross yield / plant (34.094%, 30.553%), average weight of fruit (30.558%, 29.13%), locules / fruit (28.549%, 25.050%), and ascorbic acid (23.641%, 20.919%) respectively, were found high across different parameters of variability. Marketable yield / plant (95.043%, 45.633%), marketable fruits /plant (94.68%, 68.252%), titrable acidity (93.467%, 48.838%), average weight of fruit (90.877%, 57.206%), gross yield / plant (80.305%, 56.402%), ascorbic acid (78.295%, 38.130%), and locules / fruit (76.985%, 45.276%) were found with high heritability and high genetic advance. Marketable yield / plant was significantly and positively associated with average  weight of fruit (0.734, 0.795), gross yield / plant (0.774, 0.853), marketable fruits / plant (0.734, 0.742), pericarp thickness (0.693, 0.806), ascorbic acid (0.381, 0.469), titrable acidity (0.347, 0.364) and locules/ fruit (0.284, 0.345) at both phenotypic as well as genotypic levels, respectively.  Path coefficient analysis showed that marketable fruits / plant (0.589, 0.608), gross yield / plant (0.278, 0.617) and average weight of fruit (0.382, 0.182) are the three main parameters that had the greatest positive direct impact on marketable yield / plant at the phenotypic and genotypic levels, respectively
Study of correlation and path coefficient analysis for yield attributing traits in selected rils of diverse wheat (Triticum aestivum L.) genotypes for heat tolerance
Authors: Singh Harpreet , Singh Bikram , Tiwari Sunidhi , Yadav Om Prakash , Kohli Surbhi , Ali Zafar , Kumar Rakesh
Published: June 2023

Rising temperature has adversely affected wheat production globally. In this realm we studied various morpho-physiological traits governing heat tolerance using thirty bread wheat RILs developed via crossing LOK-1 x HUW- 468, LOK 1 x HUW 234 and Raj-4014 x PBN-51. Correlation studies reflected that traits like number of tillers per plant, plant height, and chlorophyll content were significantly positive correlated with grain yield per plant, on the other hand, path coefficient analysis revealed that the chlorophyll content (0.362) and tillers per plant (0.222) showed a significant positive correlation with grain yield per plant, whereas significant negative correlation for grain yield was exhibited with relative water loss (-0.392) and canopy temperature (-0.402) at genotypic level.
Screening of Brassica genotypes against mustard aphid under northern Indian Shivalik hill conditions
Authors: Tiwari Sunidhi , Gupta S. K. , Upadhyay R.G. , Singh Harpreet , Yadav Om Prakash , Pandey Mukesh Kumar
Published: June 2023

Oilseed Brassica plays the important role in Indian agriculture in relation to oil production. The major insects in Brassicas are Lipaphis erysimi, Bagrada hilaris, Athalia lugens proxima (Klug), Chromatomyia horticola Goureau, Pieris rapae, Bagrada cruciferarum Kirkaldy are of practical importance. Out of these, the Lipaphis erysimi (Kalt.) [mustard aphid], a part of family Aphididae with order Hemiptera leads to great yield losses in rapeseed-mustard. To overcome this problem, the easiest solution is to grow resistant and tolerant varieties. The screening is done on the basis of aphid infestation index scale for categorization of the genotypes into resistance and tolerance. Experiments were carried out at the experimental farm of Division of Plant Breeding and Genetics, Faculty of Agriculture, Sher-e-Kashmir University of Agricultural Sciences and Technology, Jammu during rabi of 2017–18 and 2018–19 to evaluate mustard germplasm against Lipaphis erysimi and selecting the resistant genotypes of Brassica for its cultivation and expansion purposes. A total of fifteen cultivars were evaluated based on population buildup of mustard aphid and infestation index. The genotypes RSPN-28, CNH-11-13, RL-1359, HNS-1101, GSC-101, CNH-11-2 and HNS-1102 were found moderately resistant during the rabi 2017–2018 and during rabi 2018–2019, due to weather conditions only two genotypes CNH-13-2 and RSPN-29 were found moderately resistant and susceptible against aphid infestation.
Standardization of roots of Taraxacum officinale
Authors: Thapliyal Somesh , Ahmad Mohd. Imtiyaz
Published: June 2023

Taraxacum officinale (Dandelion) belongs to the Asteraceae family; an edible herb commonly found in subtropical and temperate regions worldwide. Traditionally dandelion is used in diarrhea, gout, jaundice, diabetes, pneumonia, urinary problems and to purify the blood. The phytochemical study of dandelion discovered the occurrence of β- sitosterol, stigmasterol, taraxsterol, lactucopicrin, lactucin, cichorin, taraxacoside, taraxacerin, campesterol, homotaraxasterol, etc. Anti-inflammatory, immunostimulating, antimicrobial, antioxidant and antidiabetic activities of dandelion were studied. This plant has great therapeutic value and in order to overcome the problem of adulteration, the present study was aimed to standardize and preserve the quality parameters of the plant. Roots of Taraxacum officinale were subjected to measurements including macroscopy, microscopy, foreign organic content, ash value, extractive value, phytochemical screening, fluorescence analysis and chromatographic analysis. HPTLC analysis confirmed the presence of various phytocomponents. The macroscopic, microscopic and physico-chemical criteria presented here can help to identify the drug and to prepare the monograph.
Humanitarian assistance in cases of natural disasters and the 2023 earthquake in Turkey and Syria
Authors: Khater Maya
Published: June 2023

Natural disasters represent a grave danger that threatens the countries of the world as a whole due to the enormous losses that result from them at all human, economic, social, and environmental levels, which justifies the urgent need for international cooperation in providing humanitarian and relief assistance to the victims affected by these disasters. The importance of research related to the legal scope of humanitarian aid in cases of natural disasters appears with the increase in the frequency and intensity of disasters, the growing losses resulting from them, and the insufficiency of the material or technical capabilities to rescue the victims. Hence, there is a need for a regulating and binding law for the international community that is more stringent and enjoys the spontaneity and speed of the initiative in the moment of disaster. The recent events of the massive earthquake that struck southern Turkey and northern Syria revealed a significant gap in the mechanisms of dealing with the disaster after it occurred, which doubled the human and economic losses in particular. This is especially true with transparency and objectivity in presenting the dimensions and limits of the disaster through media coverage and social media.
Natural extracts from Marchantia polymorpha against plant pathogens growth inhibition
Authors: Singh Shivom , Gore Shivani , Gupta Sheetanshu , Singh Gourav Kumar
Published: June 2023

The health of plants, animals, and humans is seriously threatened by the production of toxins by bacteria and fungi. The aim of the current work is to find a dependable and eco-friendly microorganism biocontrol technique to alleviate this concern. In this work, the antibacterial abilities of Marchantia polymorpha (liverwort) extracts were examined. These extracts were collected from several altitudinal ranges in the Kumaon region in Uttarakhand province, India, in the western Himalayas. Using microbroth dilution methods, the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum fungicidal concentration (MFC) of the crude extracts were determined. The results demonstrated that the Marchantia polymorpha extracts exhibited potent antifungal activity against Macrophominaphaseolina, Fusarium oxysporum, Rhizoctonia solani, and Colletotrichum acutatum, as well as antibacterial activity against Pseudomonas syringae, Xanthomonas campestris, Staphylococcus aureus, and Bacillus subtilis. According to the study results, Marchantia polymorpha extracts may have applications as natural antimicrobials in a number of sectors, including medications, agriculture, and preserving food. The research we performed demonstrates the potential of liverwort extracts as a promising biocontrol agent against bacterial and fungal diseases and as an inducer of plant disease resistance, providing a safer and more environmentally friendly alternative to synthetic chemicals that is beneficial to both human health and the environment.
Impacts of hand sanitizer on human health and environment: a review
Authors: Bala Shashi , Ahamad Faheem
Published: June 2023

Although the use of sanitizer starts around the middle of twentieth century but it becomes popular in early twenty first century (second decade of twenty first century during COVID-19 pandemic). To prevent the spread of COVID-19, World Health Organisation (WHO) recommended the use of sanitizers made up with different combinations of isopropyl alcohols, ethanol and hydrogen peroxides. Literature suggests some toxic effect of use and misuse of these components of sanitizers. Therefore, in the present study an attempt has been made to investigate the use of available hand sanitizers and their adverse effects on human body as well as to collect and correlate the gathered information with their occupation which may further trigger the adverse effect of sanitizer on human being. Out of the total respondents, 98% are using but very few (2%) are not using any type of sanitizer. Age group 2 (16-25 years) is the largest user of hand sanitizer which shows the maximum awareness of this age group related to sanitation and hygiene. Data obtained suggests that males (57.5%) are more aware to sanitization in comparison to female (41.8%). Among the total respondents, house wives were very few (0.8%) which shows lack of awareness among them may be due to their busy schedule and household works. The obtained data revealed that education plays a key role in the spread of sanitation and hygiene awareness. Most of the peoples are using the sanitizers of established brands (Dettol). The data also revealed that 88% of the respondents were observing the various impacts on the body (49% skin dryness, 16% skin allergy 12% skin irritation and itching while 12% respondents are not sure about the impacts). Only 12% peoples responded that they are not observing any impacts of sanitizer. Besides this, different components used in sanitizers pose threat to the different spheres of the environment. Based on the findings of the present study, we can conclude that sanitizer is impacting the human health and environment in various. Therefore there is a need of mass awareness regarding the use and disposal of disinfectants.
Efficiency assessment of 3.2MLD MBR based sewage treatment plant of IFFCO township Aonla, Bareilly, Uttar Pradesh, India
Authors: Ruhela Mukesh , Ahamad Faheem , Bhardwaj Sweta , Gupta Utkarsh
Published: June 2023

Increasing urbanization and industrialization is continuously putting a pressure on the ground and fresh water resource in form of quality and quantity. Therefore water recycling through wastewater treatment is the need of the present hour. Therefore in the present study the efficiency of the 3.2MLD sewage treatment plant (STP) based on membrane bioreactor technology (MBR) located in Indian Farmers Fertilizer Cooperative Limited (IFFCO) township Aonla, Bareilly, Uttar Pradesh, India was studied. The plant was recently commissioned on 10th of June 2022. The plant shows highest efficiency for turbidity (98.6%) followed by total suspended solids (TSS) (95.7%), chemical oxygen demand (COD) (89.0%), iron (86.7%), and biochemical oxygen demand (BOD) (85.0%). The efficiency for the rest of the parameters is below 50%. The MBR based STP is working efficiently as the values of parameters in treated water is within the discharge standards of central pollution control board (CPCB) listed in The Environment (Protection) Rule, 1986. One of the major problems of MBR based STP reported in literature is membrane fouling which is also rectified in the current treatment plant by using sodium hypochlorite for membrane cleaning.
Efficiency of reactors composed of plant based absorbents in combination with sand and gravel for physicochemical parameters of different category water
Authors: Singh Pooja , Tiwari R. C. , Bhutiani Rakesh , Vasu  , Ahamad Faheem
Published: June 2023

According to the world Summit of sustainable Development, the major reason for lack of safe water is either scarcity of water or contamination of water sources. Therefore this study eye on developing nations, seeks to find sustainable, yet economically and socially practical solution to the problems associated with polluted water. To fulfil the objectives of the present study, two medicinal value plants Dhav (Anogeissuslatifolia wall.) and Aragvadha (Cassia fistula Linn.) were selected and absorbents were prepared from the bark of both the plants. Then the reactors were prepared using the different compositions of sand, gravel, absorbents of Dhavand Aragvadha and cotton.In this way four filter reactors were prepared. The feeding rate of raw water is maintained at 0.5 litre per hour. The results revealed that Dhav plant absorbent was found more effective thanAragvadha. All reactors shows different efficiencies for different parameters suggesting that reactors should be prepared based on need or targeted parameters. Over all reactor 4 shows better efficiency for all the parameters. The main exclusivity of the present reactor is low cost with no electricity demand. The prepared reactors are environment friendly and easily implementable but further study is required to prove it on large scale.
E-LOGiSTİKA KANALININ SEÇİLMƏSİ PROSESİNDƏ UYĞUN ERP PROQRAM TƏMİNATININ SEÇİLMƏSI ZAMANI TƏCHIZATÇI SEÇİMİNƏ DAİR TƏTBİQ
Authors: Cavid Suleymanov, Ilkin Manafov Cavid Suleymanov, Ilkin Manafov
Published: June 2023

Logistika təcrübəsi olan şirkətlər üçün ERP sifarişlərin ilkin mərhələsindən başlayaraq tədarüklərin, inventarların və hətta daşınmaların idarə edilməsi vasitəsilə bütün axınları və vacib məlumatları mərkəzləşdirmək üçün ideal vasitədir. Təchizat zəncirinin idarə edilməsinin artan mürəkkəbliyi ilə üzləşən logistlər səmərəliliyi, sürəti artırmaq və beləliklə, tədarük zəncirinin düzgün işləməsinə mane ola biləcək səhvləri və gecikmələri məhdudlaşdırmaq üçün fəaliyyətlərinin rəqəmsal transformasiyasına başlamalı və ya davam etdirməlidirlər. Logistika ERP proqramı həm də ticarətin davamlı təkamülünə, rəqabətin təzyiqinə və müştərilərin artan tələblərinə cavab verməyə imkan verir.
Tədqiqat obyekti olan şirkətlərin təchizatçı seçimi problemini həll etmək üçün oxşar sahələr üzrə tətbiqlər üçün ədəbiyyata baxış keçirilmişdir. Yoxlama nəticəsində bu tədarükçülərin AHP və TOPSIS üsulları ilə müəyyənləşdirilməsinə qərar verildi. Təhlil çərçivəsində kriteriyalar müəyyən edilmiş və hər şirkətdən 1 nəfər ERP menecer olmaqla cəmi 3 mütəxəssisdən ibarət komanda ilə sorğu keçirilmişdir. AHP metodu ilə kriteriyalar arasında iyerarxik quruluş yaradılmış və kriteriya çəkiləri hesablanmış, TOPSIS metodu ilə alternativlər arasında sıralama aparılmışdır.
Açar sözləri: ERP, logistika, elektron ticarət.
ULTRASƏS DOPPLER SİSTEMLƏRİNDƏ QANIN AXIN İSTİQAMƏTİNİN MÜƏYYƏN EDİLMƏSİNDƏ RƏQƏMSAL METODUN TƏTBİQİ VƏ SİMULYASİYASI
Authors: Ləman Niftəliyeva, Akif Xıdırov Ləman Niftəliyeva, Akif Xıdırov
Published: June 2023

Uzun müddətdir ki, ürək-damar sistemi xəstəlikləri olduqca aktual mövzu olaraq tibb sahəsini əhatə edir. Qan axını, damar patologiyalarını aşkarlamaq üçün müasir dövrdə müxtəlif diaqnostik vasitələrdən istifadə olunsa da, ultrasəs metodlarının tətbiq istiqamətləri olduqca müxtəlifdir. Ultrasəs texnikalarından istifadə olunaraq qan dövranı və qan axını parametrlərini müəyyən edən yalnız bir neçə üsul var. Bu metodlar arasında, ultrasəs Doppler metodu xüsusi mövqeyə malikdir. Müasir dövrdə tətbiq imkanlarının genişlənməsi onun istifadəsini daha da təkminləşdirmiş və dəqiqləşdirmişdir. Hazırda, qan-damar xəstəliklərinin diaqnostikası zamanı qan axınının sürət və istiqamətinin təyini və damar rekonstruktiv əməliyyatlarının nəticələrinin qiymətləndirilməsi üçün bu metoddan istifadə etmək olduqca əhəmiyyətli hesab olunur.
Orqanizmdə qan axını dedikdə, qanın damarlar vasitəsilə arteriyalara, kapilyarlara və daha sonra venaya doğru hərəkəti nəzərdə tutulur. Orqanizmdə baş verən bu dövran onun həyat fəaliyyəti üçün olduqca əhəmiyyətli hesab olunur. Digər mayelərlə qanın axını ilə bağlı ortaq cəhət onun yüksək təzyiqli bölgədən aşağı təzyiqli sahəyə axmasıdır. Bu zaman təzyiq dedikdə, qan axını prosesində qanın damar divarlarına qarşı göstərdiyi təzyiq qüvvəsi nəzərdə tutulur. Qanın axın istiqaməti isə aşağı və ya almaqda olan təzyiq gradientinə uyğun olaraq, eyni istiqamətdə axır. Məhz bunu nəzərə alaraq deyilir ki, qanın axın istiqaməti arteriyalardan kapilyarlara sonra isə venalara doğru hərəkətdədir.
Ultrasəs müayinələri zamanı hansı parametrlərin təyin edilməsindən asılı olaraq müxtəlif görüntüləmə rejimlərindən istifadə olunur. Doppler rejimləri özlüyündə müxtəlif formada qruplaşsa da, qan axının istiqamətinin təyini zamanı məhz Rəngli Doppler rejimindən istifadə olunur. Məqalədə qırmızı qan hüceyrələrinin ötürücüyə doğru və ya əksinə istiqamətdə hərəkətinin bu rejimdə mavi və qımızı rənglərin yaranmasına necə təsir etdiyi də nəzərdən keçirilib.
Qeyd etdiyimiz kimi, Doppler ultrasəs sistemləri qan-damar xəstəliklərinin diaqnostikasında geniş şəkildə istifadə edilir. Demək olar ki, əksər doppler sistemlərində çıxışda əldə olunan Doppler siqnalında kvadrat demodulyasiya texnikasını istifadə edirlər. Bu zaman həm irəli, eyni zamanda, əksinə qan axını siqnallarının araşdırılması və tədqiqi zamanı əlavə istiqamətlərə ehtiyac duyulur. Bu zaman analoq üsullarından fərqli olaraq rəqəmsal metodun tətbiqi üstünlük təşkil edəcəkdir. Rəqəmsal metodda da Sürətli Furye Çevrilməsi (FFT) yanaşmasından istifadə olunaraq siqnallar üzərində əməliyyatlar aparılır. Məqalədə hə rəqəmsal metodun mahiyyəti, əhəmiyyəti, tətbiq imkanları, eləcə də, proqram mühitində simulyasiyası göstərilmişdir.
Açar sözlər: Doppler siqnal, rəngli Doppler, rəqəmsal metod, istiqamətin aşkarlanması