bluuebunny/crossref_metadata_2025 huggingface dataset:
On the Stability and Homogeneous Ensemble of Feature Selection for Predictive Maintenance: A Classification Application for Tool Condition Monitoring in Milling
Authors: Assafo Maryam , Städter Jost Philipp , Meisel Tenia , Langendörfer Peter
Published: May 2023

Feature selection (FS) represents an essential step for many machine learning-based predictive maintenance (PdM) applications, including various industrial processes, components, and monitoring tasks. The selected features not only serve as inputs to the learning models but also can influence further decisions and analysis, e.g., sensor selection and understandability of the PdM system. Hence, before deploying the PdM system, it is crucial to examine the reproducibility and robustness of the selected features under variations in the input data. This is particularly critical for real-world datasets with a low sample-to-dimension ratio (SDR). However, to the best of our knowledge, stability of the FS methods under data variations has not been considered yet in the field of PdM. This paper addresses this issue with an application to tool condition monitoring in milling, where classifiers based on support vector machines and random forest were employed. We used a five-fold cross-validation to evaluate three popular filter-based FS methods, namely Fisher score, minimum redundancy maximum relevance (mRMR), and ReliefF, in terms of both stability and macro-F1. Further, for each method, we investigated the impact of the homogeneous FS ensemble on both performance indicators. To gain broad insights, we used four (2:2) milling datasets obtained from our experiments and NASA’s repository, which differ in the operating conditions, sensors, SDR, number of classes, etc. For each dataset, the study was conducted for two individual sensors and their fusion. Among the conclusions: (1) Different FS methods can yield comparable macro-F1 yet considerably different FS stability values. (2) Fisher score (single and/or ensemble) is superior in most of the cases. (3) mRMR’s stability is overall the lowest, the most variable over different settings (e.g., sensor(s), subset cardinality), and the one that benefits the most from the ensemble.
Dual-Modal Electrical Imaging of Two-Phase Flow—Experimental Evaluation of the State Estimation Approach
Authors: Arif M. Ziaul , Seppänen Aku , Kolehmainen Ville , Vauhkonen Marko
Published: May 2023

Accurate measurement of two-phase flow quantities is essential for managing production in many industries. However, the inherent complexity of two-phase flow often makes estimating these quantities difficult, necessitating the development of reliable techniques for quantifying two-phase flow. In this paper, we investigated the feasibility of using state estimation for dynamic image reconstruction in dual-modal tomography of two-phase oil–water flow. We utilized electromagnetic flow tomography (EMFT) to estimate velocity fields and electrical tomography (ET) to determine phase fraction distributions. In state estimation, the contribution of the velocity field to the temporal evolution of the phase fraction distribution was accounted for by approximating the process with a convection–diffusion model. The extended Kalman filter (EKF) and fixed-interval Kalman smoother (FIKS) were used to reconstruct the temporally evolving velocity and phase fraction distributions, which were further used to estimate the volumetric flow rates of the phases. Experimental results on a laboratory setup showed that the FIKS approach outperformed the conventional stationary reconstructions, with the average relative errors of the volumetric flow rates of oil and water being less than 4%. The FIKS approach also provided feasible uncertainty estimates for the velocity, phase fraction, and volumetric flow rate of the phases, enhancing the reliability of the state estimation approach.
La Cumbre Iberoamericana de Santo Domingo. Una hoja de ruta marcada por la digitalización, la sostenibilidad, la seguridad alimentaria y el medio ambiente
Authors: Morán Blanco Sagrario , Díaz Barrado Cástor M.
Published: May 2023

La reciente Cumbre Iberoamericana, celebrada en Santo Domingo en marzo de 2023, pone de relieve una vez más la capacidad de este foro para sobrevivir en un entorno político y económico en el que el multilateralismo y los esquemas de integración se ven frecuentemente abocados al fracaso. Con todas las deficiencias que se quiera, la Cumbre Iberoamericana sigue en la línea de profundizar en la concertación política y la cooperación entre los iberoamericanos; y diseña lineamientos para la política exterior de los países de la región. En la reunión de República Dominicana se decidió seguir el camino de cumbres anteriores y situar los acentos en el campo del desarrollo sostenible y el cumplimiento de la Agenda 2030. Pero, al mismo tiempo, se intenta lograr resultados tangibles y que se abandone definitivamente la retórica, como componente del quehacer iberoamericano. Por esto, no debe sorprender que finalmente se haya llegado a acuerdos y compromisos que quedan plasmados en tres instrumentos de gran valor político y que servirán de guía en el comportamiento de los países de la región. En particular, la elaboración de la Carta Medioambiental Iberoamericana, la puesta en marcha de una Carta Iberoamericana de Principios y Derechos en los Entornos Digitales, y la edificación de una Ruta Crítica para Alcanzar una Seguridad Alimentaria Incluyente y Sostenible en Iberoamérica. Todas estas realizaciones son analizadas en el presente artículo, con visión crítica y analítica.
The generalization of some results for Schurer and Schurer-Stancu operators
Authors: Miclăuş Dan
Published: May 2023

In the present paper we generalize some results for Schurer and Schurer-Stancu operators. Firstly, we establish a general formula concerning calculation of test functions by Schurer operators. Secondly, using this relationship and some known results we prove in every case a Voronovskaja type theorem, the uniform convergence and the order of approximation for Schurer and Schurer-Stancu operators.
On the refinements of Jensen Mercer's inequality
Authors: Khan M. Adil , Khan Asif R. , Pečarić J.
Published: May 2023

In this paper we give refinements of Jensen-Mercer's inequality and its generalizations and give applications for means. We prove \(n\)-exponential convexity of the functions constructed from these refinements. At the end we discuss some examples.
On Newton's method using recurrent functions under hypotheses up to the second Fréchet derivative
Authors: Argyros Ioannis K. , Hilout Saïd
Published: May 2023

We provide semilocal result for the convergence of Newton method to a locally unique solution of an equation in a Banach space setting using hypotheses up to the second Fréchet-derivatives and our new idea of recurrent functions. The advantages of such conditions over earlier ones in some cases are: finer bounds on the distances involved, and a better information on the location of the solution.
Some general Kantorovich type operators
Authors: Braica Petru I. , Pop Ovidiu T.
Published: May 2023

A general class of linear and positive operators of Kantorovich-type is constructed. The operators of this type which preserve exactly two test functions from the set \(\{e_0, e_1, e_2\}\) are determined and their approximation properties and convergence theorems are studied.
The approximation of bivariate functions by modified bivariate operators and GBS operators associated
Authors: Pop Ovidiu T.
Published: May 2023

In this paper we demonstrate a Voronovskaja-type theorem and approximation theorem for a class of modified operators and Generalized Boolean Sum (GBS) associated operators obtained (see (3)) from given operators.
Simultaneous proximinality in \(L^{\infty}(\mu,X)\)
Authors: Abu-Sirhan Eyad
Published: May 2023

Let \(X\) be a Banach space and \(G\) be a closed subspace of \(X\). Let us denote by \(L^{\infty}\left( \mu,X\right) \) the Banach space of all \(X\)-valued essentially bounded functions on a \(\sigma\)-finite complete measure space \(\left( \Omega,\Sigma,\mu\right) .\) In this paper we show that if \(G\) is separable, then \(L^{\infty}\left( \mu,G\right) \) is simultaneously proximinal in \(L^{\infty}\left( \mu,X\right) \) if and only if \(G\) is simultaneously proximinal in \(X.\)
Sharp inequalities for the Neuman-Sandor mean in terms of arithmetic and contra-harmonic means
Authors: Chu Yu-Ming , Wang Miao-Kun , Liu Bao-Yu
Published: May 2023

In this paper, we find the greatest values \(\alpha\) and \(\lambda\), and the least values \(\beta\) and \(\mu\) such that the double inequalities \[C^{\alpha}(a,b)A^{1-\alpha}(a,b)<M(a,b)<C^{\beta}(a,b)A^{1-\beta}(a,b)\] and

\begin{align*}

&[C(a,b)/6+5 A(a,b)/6]^{\lambda

}\left[C^{1/6}(a,b)A^{5/6}(a,b)\right]^{1-\lambda}<M(a,b)<\\

&\qquad<[C(a,b)/6+5

A(a,b)/6]^{\mu}\left[C^{1/6}(a,b)A^{5/6}(a,b)\right]^{1-\mu}

\end{align*}

hold for all \(a,b>0\) with \(a\neq b\), where \(M(a,b)\), \(A(a,b)\) and \(C(a,b)\) denote the Neuman-Sándor, arithmetic, and contra-harmonic means of \(a\) and \(b\), respectively.
Localization results for the Lagrange max-product interpolation operator based on equidistant knots
Authors: Coroianu Lucian , Gal Sorin G.
Published: May 2023

In the class of strictly positive functions strong localization results are obtained in approximation by the Lagrange max-product interpolation operators based on equidistant nodes. The results allow to approximate locally bounded strictly positive functions with very good accuracy. Then, it is observed that the results can be extended to bounded functions of variable sign.
Multivariate error function based neural network approximations
Authors: Anastassiou George A.
Published: May 2023

Here we present multivariate quantitative approximations of real and complex valued continuous multivariate functions on a box or \(\mathbb{R}^{N},\) \(N\in \mathbb{N}\), by the multivariate quasi-interpolation, Baskakov type and quadrature type neural network operators. We treat also the case of approximation by iterated operators of the last three types. These approximations are derived by establishing multidimensional Jackson type inequalities involving the multivariate modulus of continuity of the engaged function or its high order partial derivatives. Our multivariate operators are defined by using a multidimensional density function induced by the Gaussian error special function. The approximations are pointwise and uniform. The related feed-forward neural network is with one hidden layer.
The eigenstructure of some positive linear operators
Authors: Attalienti Antonio , Raşa Ioan
Published: May 2023

Of concern is the study of the eigenstructure of some classes of positive linear operators satisfying particular conditions. As a consequence, some results concerning the asymptotic behaviour as \(t\to +\infty\) of particular strongly continuous semigroups \((T(t))_{t\geq 0}\) expressed in terms of iterates of the operators under consideration are obtained as well. All the analysis carried out herein turns out to be quite general and includes some applications to concrete cases of interest, related to the classical Beta, Stancu and Bernstein operators.
Proceso de atención de enfermería en el cuidado al paciente COVID-19
Authors: Valle-Dávila María Fernanda , Flores Grijalba Mercedes del Carmen , Acosta Balseca Silvia Lorena , Vásquez Figueroa Tatiana Isabel , Morejón Jácome Gladys Edelmira
Published: May 2023

El  profesional  de  enfermería  ha  desempeñado  un  rol  fundamental  en  el  cuidado  al  paciente  durante  la  pandemia  por  COVID-19.  Las  acciones  de  enfermería en el cuidado al paciente están sustentadas en el Proceso de Atención de Enfermero (PAE). Objetivo. Describir los parámetros de valoración, diagnósticos e intervenciones que los profesionales de enfermería aplicaron en sus procesos de atención al paciente diagnosticado con COVID-19. Materiales y método.  Estudio de abordaje cuantitativo y descriptivo, la población estuvo constituida por 240 profesionales de enfermería que laboraron en servicios de atención al paciente COVID-19 en 4 hospitales públicos de la Zona 1 del Ecuador, se aplicó un cuestionario de 21 preguntas de tipo Likert. Resultados. La valoración al paciente se ejecutó mayoritariamente a través de las 14 Necesidades Básicas descritas por Henderson. Entre los diagnósticos más priorizados se encuentran patrón respiratorio ineficaz, deterioro del intercambio gaseoso y deterioro de la respiración espontánea. Las intervenciones más frecuentes fueron oxigenoterapia, ayuda a la ventilación y monitorización respiratoria, termorregulación y manejo de ventilación mecánica no invasiva, manejo de la vía aérea y monitorización de signos vitales. Conclusiones. Se concluye que la aplicación del proceso de atención de enfermería es fundamental en la práctica profesional, con la valoración integral, diagnósticos priorizados e intervenciones se contribuyó a mejorar y mantener el estado de salud de los pacientes. En este sentido es fundamental el fortalecimiento de esta metodología propia de la disciplina a través de su aplicación.
THE PERFORMANCE AND SEAMLESSNESS ANALYSIS OF LTE NETWORK BY SDN METHODS USING
Authors: Садыков И.С. , Хашумов И.У. , Занаева З.С.
Published: May 2023

Мобильность пользовательского оборудования (UE) в сотовой сети является сложной задачей с точки зрения контроля и управления. Текущая традиционная передача обслуживания в сети Long-Term Evolution (LTE) управляется усовершенствованным узлом B или eNodeB (eNB), который представляет собой децентрализованное решение. В отличие от существующей технологии, программно-определяемая сеть (SDN) имеет возможность обслуживать пакеты коммутационного оборудования без участия контроллера SDN, за исключением первого. В соответствии с нашим решением «бесшовный» переход активного мобильного устройства из зоны действия одной базовой станции в зону действия другой без разрыва соединения - так называемый «хэндовер» (handover) управляется контроллером SDN, который отслеживает общее управление сетью и диктует записи потоков для коммутаторов OpenFlow в сети. Из результатов исследования будет видно, что наш подход отслеживает всю сеть на централизованном контроллере с улучшенной производительностью.

User equipment (UE) mobility in a cellular network is a complex task in terms of control and management. The current legacy Long-Term Evolution (LTE) network handoff is managed by an evolved Node B or eNodeB (eNB), which is a decentralized solution. Unlike existing technology, software-defined network (SDN) has the ability to serve packets of switching equipment without the participation of the SDN controller, except for the first one. In accordance with our solution, a "seamless" transition of an active mobile device from the coverage of one base station to the coverage of another without breaking the connection - the so-called "handover" (handover) is controlled by the SDN controller, which monitors the overall management of the network and dictates flow records for OpenFlow switches online. From the results of the study, it will be seen that our approach monitors the entire network on a centralized controller with improved performance.
THE PROSPECT OF USING GRAPHENE BATTERIES: THE FUTURE OF HYBRID BATTERIES
Authors: Аветисян А.С.
Published: May 2023

Данная научно-исследовательская работа была посвящена практическому применению графена в сфере энергетики, а именно в создании аккумуляторов будущего. Выполнен анализ и раскрыта перспектива применения графена в создании гибридных батарей, имеющие преимущества по сравнению литий-ионными аккумуляторами.

This research work was devoted to the practical application of graphene in the field of energy, namely in the creation of batteries of the future. The analysis is carried out and the prospect of using graphene in the creation of hybrid batteries, which have advantages over lithium-ion batteries, is revealed.
PROBLEMS AND TRENDS OF EDUCATION IN THE MODERN WORLD
Authors: Алисултанова Э.Д. , Бетербиева А.И. , Шудуева З.А. , Умарова Л.С.
Published: May 2023

В статье рассматриваются основные проблемы, а также тренды, которые в будущей системе образования связывают не только с поиском новых форматов обучения, но и новых ролей для всех участников образовательного процесса.

The article discusses the main problems, as well as trends that in the future education system are associated not only with the search for new learning formats, but also new roles for all participants in the educational process.
DIGITAL PEDAGOGY AS A FACTOR OF IMPROVING THE EDUCATIONAL SERVICES QUALITY
Authors: Моисеенко Н.А. , Эрзанукаева М.М.
Published: May 2023

В статье обосновывается идея поддержки и просвещения академического персонала, чтобы сделать осознанный выбор того, как они используют технологии для поддержки учебной программы.

The article substantiates the idea of supporting and educating academic staff to make informed choices about how they use technology to support the curriculum.
CURRENT PROBLEMS OF MODERN EDUCATION DIGITAL TRANSFORMATION
Authors: Карпенко О.А.
Published: May 2023

В настоящий момент все общество и экономика подвергается интенсивной цифровизации, в результате которой неизбежно возникают всевозможные проблемы, несоответствия и казусы, влияющие на те или иные аспекты человеческой жизнедеятельности и психического здоровья.Особенно значимыми являются трансформационные проблемы, связанные с цифровизацией в системе образования. Отметим и кратко охарактеризуем наиболее значимые и актуальные проблемы, возникающие в связи с переходом к цифровизации образовательного процесса.

At the moment, the entire society and economy is undergoing intensive digitalization, as a result of which all sorts of problems, inconsistencies and incidents inevitably arise that affect certain aspects of human life and mental health.Particularly significant are the transformational problems associated with digitalization in the education system. We will note and briefly characterize the most significant and urgent problems that arise in connection with the transition to digitalization of the educational process.
NEW TECHNOLOGIES STIMULATE THE POTENTIAL OF THE EDUCATION OF THE FUTURE
Authors: Хаджиева Л.К. , Бахарчиев С.Х.
Published: May 2023

В данной статье рассматривается перспективы развития образования будущего благодаря использования новых технологий в образовании, что дает новый виток развития. Во многих мировых образовательных учреждениях, были представлены новейшие достижения и тенденции развития в области smart-образования, а также Были обсуждены элементы и характеристики информационных технологий, поддерживающих развитие образования в особых обстоятельствах, программы и проблемы, создание международной платформы для исследований, обмена и сотрудничества в области образования, а также содействие построению сообщества общего будущего в человеческом киберпространстве.

This article discusses the prospects for the development of education of the future through the use of new technologies in education, which gives a new round of development. In many world educational institutions, the latest achievements and development trends in the field of smart education were presented, and the elements and characteristics of information technologies that support the development of education in special circumstances, programs and problems were discussed, creating an international platform for research, exchange and cooperation in the field of education, as well as the promotion of building a community of a shared future in human cyberspace.
THE USE OF CANONICAL TASKS OF LINEAR PROGRAMMING IN THE PRACTICE OF TEACHING HIGHER MATHEMATICS
Authors: Насибуллин Д.Р.
Published: May 2023

В прикладной математике большое внимание уделяется целому классу задач оптимизации, заключающихся в нахождении в заданной области точек наибольшего или наименьшего значения некоторой функции, зависящей от большого числа переменных. Это так называемые задачи математического программирования. Они возникают в самых разных областях человеческой жизни и деятельности, чаще всего в экономических исследованиях, в планировании и организации производства. Изучение этих задач и методов их решения привело к созданию такой научной дисциплины, как линейное программирование. Поскольку экономика является неизменным ядром человеческой жизни и деятельности, то решение таких задач для дальнейшего эффективного построения процессов является необходимым, поэтому данная тема является актуальной.

In applied mathematics, much attention is paid to a whole class of optimization problems, which consist in finding the maximum or minimum value of a certain function depending on a large number of variables in a given area of points. These are the so-called problems of mathematical programming. They arise in various areas of human life and activity, most often in economic research, in planning and organizing production. The study of these problems and methods for solving them led to the creation of such a scientific discipline as linear programming. Since the economy is the invariable core of human life and activity, the solution of such problems is necessary for the further effective construction of processes, therefore this topic is relevant.
LAWS OF MACRO- AND MICRO- MATTER
Authors: Хаджиев Р.Р. , Янарсаев А.В.
Published: May 2023

Физика ХХ в. Породила революция в естествознании, которая охватила сначала собственно физику, потом под влиянием физики химию, биологию, астрономию, медицину и т.д. Физика является основной естественнонаучной дисциплиной, потому что она имеет дело с такими свойствами мира, как время, пространство, материя, движение, электричество, излучения, свет.

Physics of the twentieth century. It gave rise to a revolution in natural science, which first embraced physics proper, then, under the influence of physics, chemistry, biology, astronomy, medicine, etc. Physics is the main natural science discipline, because it deals with such properties of the world as time, space, matter, motion, electricity, radiation, light.
USING ARTIFICIAL INTELLIGENCE BY A TEACHER TO IMPROVE THE EFFECTIVENESS OF TEACHING STUDENTS IN ONLINE EDUCATION
Authors: Разумнова В.О.
Published: May 2023

В данной статье представлены результаты исследования по использованию ИИ в обучении школьников средних и старших классов для фиксирования обратной связи при проведении дистанционных занятий. Было проведено анкетирование среди 157 учителей средних и старших классов в возрастном диапазоне 25-45 лет с 2021-2022 года по проблемам дистанционного обучения. Установлено, что наиболее важной проблемой в дистанционном образовании представляет недостаток невербальной связи между учителем и учеником. Для решения данной проблемы была предложена методика внедрения основных признаков невербального общения в ИИ с использованием машинного обучения.

This article presents the results of a study on the use of AI in teaching middle and high school students to record feedback during distance learning. A survey was conducted among 157 middle and high school teachers in the age range of 25-45 years from 2021-2022 on the problems of distance learning. It is established that the most important problem in distance education, there is a lack of non-verbal communication between a teacher and a student. To solve this problem, a method was proposed for introducing the main features of nonverbal communication in AI using machine learning.
INFORMATION AND COMMUNICATION COMPETENCE OF THE TEACHER AS THE BASIS OF THE MODERN LEARNING METHOD
Authors: Насибуллин Д.Р. , Мальцев И.В. , Ещеркина Л.В.
Published: May 2023

В настоящее время информационные и компьютерные технологии развиваются быстрыми темпами, поэтому в образовательных учреждениях активно внедряются новые подходы к обучению. В статье рассматриваются аспекты использования мультимедийных презентаций в образовательном процессе, их роль, функции, возможности и требования к их разработке.Цифровые методы могут способствовать созданию важных предпосылок для дальнейшего развития технических, коммуникативных и творческих знаний, поэтому данная тема является особенно актуальной.

Currently, information and computer technologies are developing at a rapid pace, so new approaches to learning are being actively introduced in educational institutions. The article discusses aspects of the use of multimedia presentations in the educational process, their role, functions, capabilities and requirements for their development.Digital methods can contribute to the creation of important prerequisites for the further development of technical, communicative and creative knowledge, so this topic is particularly relevant.
EYETRACKING AS AN INNOVATIVE DIGITAL NEUROTECHNOLOGY IN ALTERNATIVE COMMUNICATIONCHILDREN WITH CEREBRAL PALSY
Authors: Семенова Т.Н.
Published: May 2023

В статье раскрывается особенности технологии айтрекинга - дистанционного отслеживания направления взора человека и регистрации положения глаз в процессе работы с компьютером в целях коммуникации и обучения неговорящих детей. В частности, поднимается актуальность использования данного оборудования в работе с детьми с нарушениями опорно-двигательного аппарата.

The article reveals the features of the eyetracking technology - remote tracking of the direction of a person's gaze and registering the position of the eyes while working with a computer for communication and teaching non-speaking children. In particular, the relevance of using this equipment in working with children with disorders of the musculoskeletal system is raised.
Serbest Formlu İnce Cidarlı AA 5083-H111 Alaşımının Frezelenmesinde Kesme Parametrelerinin Yüzey Pürüzlülüğü Üzerine Etkilerini Deneysel ve İstatiksel Değerlendirilmesi
Authors: ÖZLÜ Barış , ÇELİK Uğurcan , DEMİR Halil
Published: May 2023

Bu çalışmada, kuru işleme koşullarında serbest formlu ince cidarlı AA 5083-H111 alaşımın kaplamasız karbür parmak freze ile işlenmesinde cidar kalınlığının, kesme hızının ve ilerleme miktarının yüzey pürüzlülüğü üzerindeki etkilerinin belirlenmesine odaklanmıştır. Ayrıca en düşük yüzey pürüzlülüğü için optimum kesme parametrelerinin belirlenmesinde Taguchi yöntemi ve regresyon analizi uygulanmıştır. Deney tasarımı Taguchi L32 (21x42) dizinine göre hazırlanmıştır. Deney ve analiz sonuçlarına göre, yüzey pürüzlülüğünü en aza indirmek için optimum kesme parametre seviyeleriA2B1C4 (5 mm cidar kalınlığı, 0,05 mm/diş ilerleme miktarı ve 200 m/dak) belirlenmiştir. ANOVA analiz sonucuna göre yüzey pürüzlülüğü üzerine en etkin kesme parametresi %57,14 ile ilerleme miktarı olduğu tespit edilmiştir. Yüzey pürüzlülüğü için yapılan regresyon analiz sonuçlarında ikinci derece regresyon analiz sonuçları lineer regresyon sonuçlarına göre gerçek değerlere en yakın sonuçları verdiği görülmüştür. özet 250 kelimeyi aşmamalı ve paragraf kullanılmamalıdır.
Travma Sonrası Stres Bozukluğu (TSSB) Tedavisine Yönelik Moleküler Hedefler ve Yeniden Konumlandırılan İlaçlar
Authors: KUBAT OKTEM Elıf
Published: May 2023

Travma sonrası stres bozukluğu (TSSB), fiziksel hasar veya kaygı gibi zihinsel şok içeren bir kazayı takiben

görülen travmanın neden olduğu zihinsel bir hastalıktır. Toplumda yaygın olmasına rağmen, TSSB'nin

prognozu ve optimal terapötikleri sınırlıdır. Erken müdahale için moleküler hedefler belirsiz kaldığından,

daha iyi bir TSSB patogenezinin moleküler temellerinin anlaşılması hastalık prognozunun zorluklarını

karşılamak ve bu moleküler hedeflere yönelik teşhis ve tedavi için gereklidir. Strese maruz bırakılan

farelerin iki farklı dokusundan elde edilen mikrodizi verilerinin işlenmesi ve analiziyle yapılan bu

çalışmada, her iki tip doku için de anlatımı farklılık gösteren genler tespit edilmiş, bu genlerin

zenginleştiği yolizleri bulunmuş, bu genlerin protein protein etkileşim ağları ve bu ağlardaki hub

proteinler tespit edilmiştir. Bu hastalıkta anlatımı farklılık gösteren genlerin etkilerini tersini çevirmeye

yönelik her iki farklı tip doku için de ayrı ayrı yapılan ilaç yeniden konumlandırma çalışmalarının

karşılaştırılması sonucunda; vorinostat, homoharringtonin ve QL-XII-47 TSSB’yi iyileştirmek için yeni ilaç

adayları olarak önerilmiştir. Bu ilaçlardan vorinostat’ın, hücrede HDAC1, HDAC2, HDAC3, HDAC6, HDAC7

ve HDAC8 genlerini hedef aldığı tespit edilmiştir.
Estructuras conceptuales como modelos de representación en la extracción de conocimiento almacenado en texto no estructurado
Authors: Perez Reyes Gustavo
Published: May 2023

De las herramientas para facilitar el acceso al cúmulo de información que se genera diariamente, una de las más utilizadas es la comúnmente llamada minería de texto.  Aquí proponemos utilizar y analizar dos métodos: mapas y grafos conceptuales. Estos se caracterizan por ser una encarnación más completa del contenido almacenado con el objetivo de representar la información estructural de un texto. Ello implica un avance significativo a un nivel conceptual respecto del nivel temático propio de los modelos descriptivo y predictivos. Debido al volumen de información a procesar puede requerir una gran carga computacional, un objetivo secundario pero no menos importante es la aplicación del modelo de agentes para controlar de manera dinámica el espacio de búsqueda y optimizar los tiempos de procesamiento de los textos. El presente es un trabajo en desarrollo, centrado sobre el eje conceptual, mientras el aspecto práctico forma parte del trabajo subsecuente.
Conservación en humedales urbanos
Authors: Macagno Pablo , Grimson Rafael , Pereira Pablo , Schivo Facundo
Published: May 2023

Los humedales urbanos tienen un rol central en el contexto actual de crisis ambiental por las funciones ecosistémicas que cumplen. Resulta fundamental profundizar las políticas para su protección, considerando su fragilidad ante las alteraciones antrópicas y el paisaje en que están inmersos. En la Región Metropolitana de Buenos Aires (RMBA), a pesar de lo acelerado y caótico de su crecimiento urbano, persisten ecosistemas naturales con un razonable estado de conservación para ser preservados. En el marco de un proyecto más amplio que pretende inventariar los humedales de la RMBA y construir conocimiento sobre los tipos de ocupaciones y transformaciones que han recibido, este artículo analiza a la localidad de Gregorio de Laferrere, en el partido de La Matanza. Desde una mirada interdisciplinaria y basada en la planificación socio-ecológica, se delinean una serie de propuestas que incorporan a estos ecosistemas con una perspectiva integral del hábitat.
En torno a la representación de la guerra de Malvinas y sus límites
Authors: De Hoz Tomás
Published: May 2023

Las formas de representación operan en varios niveles. Forman parte de las disputas por el pasado y de las relaciones de poder del presente. En este artículo, ahondaremos en aquellas sobre la Guerra de Malvinas y haremos especial foco en el lugar que un cortometraje ha ocupado en la construcción de la memoria colectiva sobre el conflicto. Nos abocaremos en lo que sigue al análisis del corto Guarisove. Los olvidados de Bruno Stagnaro, estrenado en 1995, con la idea de buscar rastros de verdad en esta ficción. A través de su análisis y guiados por la teoría acerca de la representación y sus límites, veremos que Guarisove funcionó como un entrelazamiento entre imágenes y palabras en una práctica de representación que contribuyó a la relación constitutiva de la historia y la memoria de los argentinos sobre la Guerra de Malvinas.
Romper aguas
Authors: Vitullo Julieta
Published: May 2023

La autora de Islas imaginadas. La guerra de Malvinas en la literatura y el cine argentinos (Buenos Aires: Corregidor, 2012), coautora y protagonista del film La forma exacta de las islas, dirigido por Edgardo Dieleke y Daniel Casabé (2014), escribió una crónica poética sobre los hechos ocurridos en los meses siguientes a su viaje a las Islas Malvinas en 2006. Escrita y publicada originalmente en inglés en 2017 con el nombre de Broken Waters en la revista The Normal School (Universidad Estatal de California en Fresno, primavera de 2020), fue traducida especialmente para este dossier.
The Use of Agricultural Fiber in “an Economy that is Restorative and Regenerative by Design”
Authors:   University of Illinois at Urbana-Champaign, Taylor Mark , Flores Felipe ,   University of Illinois at Urbana-Champaign, Shiang Cheng-Shen ,   University of Illinois at Urbana-Champaign, Kovank Lauren ,   University of Illinois at Urbana-Champaign
Published: May 2023

This paper presents the findings of an investigation into agricultural “waste” fibers and how they can be used in “an economy that is restorative and regenerative by design”, this is the definition the Ellen MacArthur foundation uses to define a Circular Economy.
Entre jugar y gestar
Authors:   , Barcos Andrea Mónica
Published: May 2023

En la presente Tesis de Maestría se abordará el tema de los Embarazos Infantiles Forzados que se presentan cuando una niña o adolescente menor de 15 años queda embarazada, ya sea por desconocimiento o por no contar con los recursos para evitarlo en relaciones consensuadas, o como resultado de violencias sexuales. El objetivo planteado consiste en explorar y caracterizar para el período 2021/2022 en la Pcia. de Buenos Aires, las situaciones de niñas y adolescentes de hasta 14 años inclusive que transitan embarazos como resultado de la violencia sexual (violencia sexual intrafamiliar y las uniones o matrimonios tempranos entre niñas y varones adultos). Implica identificar los contextos de ocurrencia de estas gestaciones, sus causas y las modalidades de resolución. Para ello se propone una investigación de tipo exploratoria/descriptiva que, mediante el método mixto, entrame un diseño cuantitativo (datos estadísticos) a partir del metanálisis de fuentes secundarias diversas, con un diseño cualitativo que recupere las particularidades de las situaciones mediante entrevistas a trabajadoras sociales como unidades informantes. El sentido de la investigación es recuperar y visibilizar las particularidades de las niñas y adolescentes embarazadas y víctimas de violencia sexual en un orden social regido por el patriarcado y el capitalismo.
Información y Tecnologías de Información Geográfica como herramientas para la gestión de riesgo de desastre en pequeños productores agropecuarios de la provincia de Buenos Aires, entre 2000 y 2018
Authors:   , Schomwandt David
Published: May 2023

Esta obra ha tenido como finalidad contribuir en la visualización de la problemática del riesgo que presenta el pequeño productor agropecuario de la provincia de Buenos Aires. Para lo cual ha integrado distintas perspectivas, entre las que se destaca la utilización de las tecnologías de información geoespacial, junto al análisis cualitativo de las principales variables propias de la producción agropecuaria. En paralelo se ha realizado un abordaje cualitativo, interpretando las herramientas legislativas actuales, provinciales y nacionales, que posee el Estado en la gestión del riesgo. La discusión central se lleva adelante entendiendo al objeto de estudio como la vinculación indisociable entre el Estado y el productor. Como herramienta adicional en análisis de la gestión del riesgo, se abordaron las discusiones bajo la lógica de la geografía crítica, que ha sido en su mayoría ha sido planteada tanto al inicio y final de cada Capítulo. En lo que se refiere a la utilización de las tecnologías de información geográfica, estas han sido una parte relevante y transversal en el proyecto, se ha intervenido los distintos enfoques bajo el análisis y la producción de información geoespacial, construyendo y reconstruyendo pensamiento e ideas propias, como también ha sido posible contar con un importante volumen de datos de distintas vertientes tecnológicas, por lo cual y en conjunto, las tecnologías de información geoespacial han sido de gran ayuda como una herramienta de integración, análisis y visualización de los distintos escenarios de riesgo. Como resultado final de todo el proceso de investigación, se tienen como finalidad, realizar un aporte crítico sobre la gestión del Estado en lo referente a los distintos aspectos de la gestión del riesgo.
RELAÇÃO ENTRE AS TAXAS DE AMPUTAÇÃO MAIOR EM PÉ DIABÉTICO CORRELACIONADO COM O AUMENTO DA MORBIDADE EM PACIENTES IDOSOS
Authors: Henrique Soares Ferreira Paulo , do Nascimento Andrade Feitosa Ankilma , Gonçalves Vieira Aracele , Pucci Andrade de Oliveira Maximiliano , Raíssa Silva Varela Beatriz
Published: May 2023

Introdução: O pé diabético é uma das principais complicações da diabetes mellitus, tendo característica progressiva e determinando uma alta taxa de amputação dos membros inferiores. Embora sua prevenção possa ser realizada com precauções diárias comuns, o pé diabético permanece como uma condição de alto custo para o sistema de saúde, mostrando a importância da conscientização acerca dos cuidados primários e tratamento precoce. Objetivos: Observar a associação entre a alta morbidade em pacientes idosos com pé diabético que foram submetidos a amputação maior. Método: Trata-se de uma revisão integrativa, relizada a partir de um levantamento bibliográfico na Biblioteca Nacional em Saúde (BVS), LILACS e National Library of Medicine (PubMed), utilizando como Descritores em Ciências da Saúde: Amputação, Morbidade, Pé diabético e Idoso. Foram incluídos artigos baseados na temática central, publicados em português, inglês, com texto completo disponível e indexados nos referidos bancos de dados entre 2017 e 2022. Resultados: A amputação maior de membros inferiores (MMII) desencadeia um declínio da capacidade funcional do paciente idoso, contribuindo de forma significativa para um aumento da incapacidade, morbidade, mortalidade e complicações pós-cirúrgicas. Desse modo, a deteriorização do organismo em pacientes com idade avançada, associado a presença de doenças crônicas compatíveis com a faixa etária, como a Doença Arterial Periférica e a Doença Renal Crônica, tornam a condição física significativamente debilitada, tornando o organismo mais vulnerável para a realização da amputação maior aumentando e representando uma piora do prognóstico. Conclusão: O estudo permitiu esclarecer o aumento das taxas de morbidade e mortalidade em pacientes idosos com pé diabético após a realização da amputação maior. Portanto, as evidências apontam a necessidade do desenvolvimento de estratégias de saúde direcionadas para conscientização e estratificação de risco para o diagnóstico e manejo precoce, visando evitar que os pacientes portadores de fatores de risco procurem assistência quando as complicações já estiverem presentes e minimizando o aparecimento de úlceras nos pés.

PALAVRAS-CHAVE: Amputação. Morbidade. Pé diabético. Idoso.
Digital Twins: Shaping the Future of Energy Systems and Smart Cities through Cybersecurity, Efficiency, and Sustainability
Authors: Dimd Berhane Darsene , Cali Umit , Hajialigol Parisa , Moazami Amin , Gourisetti Sri Nikhil Gupta , Lobaccaro Gabriele , Aghaei Mohammadreza
Published: May 2023

This manuscript is the preprint version of a conference paper that is accepted for presentation and publication, International Conference on Future Energy Solutions (FES2023) to be held in Vaasa, Finland, 12-14, June 2023.
Feeding graph machine learning into the agent based model for network analysis
Authors: Tashakor Ghazal , Wong Alvaro , Suppi Remo
Published: May 2023

Agent-based modeling is a powerful computational tool that can simulate complex behavior based on rules in both micro and macro scales. Defining the constant agent behavior patterns rules is uncertain since it depends on many facts leading to complicated decision-making processes. Integrating machine learning, specifically into a complex multiscale multi-agent model, could provide scientists with practical tools to make decisions. It also allows him to execute unlimited datasets in a large parametric ABM simulation on HPC/ Cloud infrastructures to improve accuracy, accelerate time to solution and significantly reduce costs.

This paper presents a modeling and simulation systems workflow that allows us to mine network measures and visualizing the evolving behavior of a tumor agent based model at both molecular and cellular levels. This workflow is proposed to construct a complex, scalable network based on our simulated tumor growth agent-based model. Three applicable machine learning techniques are  combined with the traditional simulation to train the tumor network evolving. These techniques also discover and classify subgraphs.

In this Model, the front-end integration is the strength of Python modeling based on packages such as an ABM package (Mesa), analysis, and visualization packages (Numpy, SciPy, Matplotlib). On the other hand, the Tumor simulation is getting more orchestrated while united with machine learning packages (NetworkX) or distribution utility modules and third-parties (Pypi) and container facilities deep at the back-end. 

Link to the code : https://github.com/ghta1000/Mesa-NetworkX-Agent-model.git
Identification of IT Governance Capability Level of COBIT 2019 at The KOMINFO City of Bitung, North Sulawesi
Authors: Lumingkewas Cherry , Mambu Joe Yuan , Wahyudi Andria
Published: May 2023

Effective information technology governance (ITG) is vital for managing risks and ensuring proper oversight of IT in government organizations and enterprises. However, many organizations struggle with implementing effective ITG strategies, resulting in a higher likelihood of cybersecurity breaches, operational inefficiencies, and financial losses. This study addresses the urgency of improving ITG by assessing the capability level of ITG within the Ministry of Communication and Information Technology (KOMINFO) in Bitung, North Sulawesi, using the widely recognized COBIT 2019 framework. By conducting interviews with key IT personnel, the study quantifies the capability level of eleven core models and highlights areas that require improvement. The results underscore the critical importance of designing and implementing effective IT governance to mitigate risks and enhance IT oversight in government organizations and enterprises. The study's findings can serve as a foundation for future efforts to improve IT governance in KOMINFO and other organizations, ultimately contributing to a safer and more secure IT environment.
Perancangan Aplikasi Jasa Kuli Bangunan Berbasis Android Menggunakan Metode Throw-Away Prototype
Authors: Tombeng Marchel Thimoty , Muju Matthew Edgar Freeman
Published: May 2023

Tujuan dari penelitian yang peneliti lakukan yaitu merancang aplikasi jasa kuli bangunan berbasiskan android platform di Sulawesi Utara. Penelitian ini dilakukan oleh karena melihat dampak dari pandemic virus korona (COVID19) yang telah membuat banyak orang kehilangan pekerjaan dan seiring berkembangnya zaman, sudah banyak orang-orang yang mencari pekerjaan ataupun menawarkan perkerjaan lewat media internet.  Penelitian ini akan mempertemukan pihak yang membutuhkan orang untuk bekerja dan orang yang membutuhkan pekerjaan. Konsep ini didasarkan pada aplikasi-aplikasi e-commerce yang memperjual-belikan barang, tetapi yang menjadi perbedaan adalah aplikasi ini memperjual-belikan jasa. Jasa adalah suatu tindakan yang tidak kasat mata namun hasilnya dapat dilihat. Penelitian ini akan fokus dalam jasa kuli bangunan, tukang kayu, dan tukang kitchen set. Dimana jasa kuli bangunan akan membuat bangunan ataupun merenovasi bangunan, jasa tukang kayu akan membuat produk-produk dari kayu (meja, lemari, kursi), dan jasa kitchen set akan membuat kitchen set. Dalam pembuatan aplikasi ini akan menggunakan metode ‘throw-away prototyping’, dimana peneliti akan membuat suatu prototype sesuai kebutuhan pengguna agar pengguna bisa mendapat gambaran dari aplikasi, kemudian mengimplementasikannya menjadi aplikasi. Jadi, kesimpulannya pembuatan aplikasi ini ditujukan untuk memudahkan masyarakat dalam mencari pekerja dan pekerjaan yang berkaitan dengan bangunan. Dalam penelitian ini, peneliti telah membuat aplikasi dan mengimplementasikan rancangan yang ada sehingga dapat menghasilkan aplikasi yang operasional dan sesuai dengan kebutuhan dari pengguna.
PECULIARITIES OF FOREIGN LANGUAGE TEACHING IN MIXED-ABILITY GROUPS OF NON- LINGUISTIC SPECIALITIES
Authors:   Volodymyr Vynnychenko Central Ukrainian State Pedagogical University, Habelko Olena
Published: May 2023

There are many strategies that can be put into practice to meet the needs of all students, but unfortunately, no "magic method" will guarantee every student's academic success. Today, most schools have students of different levels and abilities, which is a challenge for teachers. The teacher's goal is to reach all students by observing them in a variety of ways to achieve effective learning. Almost most students think of English as a subject they have to learn in school and do not realize that English is a language of communication that is used all over the world. A systematic approach is needed to solve these problems. Education should be aimed not at knowledge, but at skills. The article is devoted to the organization of the foreign language learning process in groups of students with different levels of foreign language proficiency. The reasons for the appearance of such groups, as well as the problems that may arise when studying in such an educational environment, are considered. The problem of heterogeneity of groups is successfully solved by using a special technology of multi- level training. In this study, it is noted that in the conditions of teaching foreign language communication of students of higher educational institutions, this technology involves diagnosing the initial level of each student and building individual learning trajectories of students in the zone of their immediate development. Methodical strategies for the implementation of multi-level differentiation are proposed, which will contribute to the effective learning of a foreign language by students of non-linguistic majors. The form of group interaction of students, which will be effective in the learning process in this format, has been determined. The expediency of using educational materials of different levels of complexity during teaching foreign language students in groups of different levels has been confirmed. The article also states that this format of work aroused interest among students, most students began to respond more actively in class. As a result, their foreign language skills improved.