bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of central pontine myelinolysis in HIV-infected patients
Authors: Konkova-Reidman A. B. , Mikheeva T. V. , Reidman P. A. , Kochetkov I. V.
Published: April 2024

Aim: to conduct a clinical and epidemiological analysis of cases of central pontine myelinolysis (CPM) in HIV-infected patients. Materials and methods. Four patients hospitalized in the infectious diseases department of No. 1 Clinic of the South Ural State Medical University were under dynamic observation. Results and its discussion. Four patients hospitalized in the infectious diseases department of Clinic No. 1 of the South Ural State Medical University were under dynamic observation. Patient management was carried out in accordance with current clinical recommendations for the provision of medical care to patients with HIV infection with a set of clinical and laboratory methods, including examination of lumbar puncture, its cytological and biochemical composition, determination of DNA of cytomegalovirus (CMV) and Epstein-Barr viruses (EBV) herpes simplex types 1 and 2, T. gondii, Cr. Neoformans, M. Tuberculosis, Cryptococcus neoformans, the presence of pathogens of bacterial infections. All patients underwent magnetic resonance imaging (MRI) of the brain. Conclusion. The process of demyelination of the central nervous system develops regardless of the level of CD4 lymphocytes and HIV viral load. The main method for verifying the diagnosis is MRI of the brain
Melanoma and basal cell skin cancer in a patient with HIV infection. Clinical observation
Authors: Efanova E. N. , Lakomova I. N. , Pavlova E. V. , Kazurova A. N.
Published: April 2024

The aim is to present the results of the anamnesis, diagnosis and treatment of a case of a combination of malignant melanoma of the skin and basal cell carcinoma of the skin in a patient with HIV infection. Material and methods. The clinical observation of the development of multiple skin lesions with malignant neoplasms (melanoma and basal cell carcinoma) against the background of HIV infection in a patient with low adherence to follow-up and antiretroviral therapy (ART) is described. Clinical and anamnestic data, results of examination and therapy are presented. Results and discussion. Malignant neoplasms of the patient’s skin were first identified by a dermatovenerologist. The patient was routed to an oncologist, fully examined and successfully treated with a combined method (surgical removal of tumors, photodynamic therapy and immunotherapy). Further observation and examination revealed the metastasis of melanoma. The above observation indicates the need for timely and comprehensive examination of people living with HIV (PLHIV) for early detection of oncological diseases. The case demonstrates the possibility of obtaining effective treatment of a malignant neoplasm of the skin against the background of immunosuppression in the short term, despite the patient’s low adherence to therapy. Conclusion. It is especially important for outpatient doctors (infectious disease specialists, dermatovenerologists, surgeons, etc.) to be oncological when working with PLHIV. It is necessary to include malignant neoplasms of the skin, including melanoma and basal cell carcinoma, in the range of differential diagnostic search for erosive ulcerative and nodular lesions. The presented case highlights the need for timely provision of comprehensive medical care and proper routing of comorbid patients.
Secondary recurrent syphilis in a patient with HIV infection. Clinical case
Authors: Serdjukova Е. А. , Popov V. V. , Chernyavskaya O. A. , Morozova N. A.
Published: April 2024

Relevance. HIV infection is a chronic sexually transmitted infectious disease. Given the single route of transmission, quite often HIV-infected patients develop a syphilitic infection. At the same time, syphilis against the background of HIV infection has its own clinical characteristics. It is important for doctors of various specialties to know these features.

Description of the case. A clinical case of secondary syphilis and early neurosyphilis in a 52-year-old patient with HIV infection is presented.

Discussion. Patients with HIV infection are characterized by unusual clinical manifestations of syphilis in the form of its malignity, atypical, severe course with the development of various complications. In the article, the authors describe atypical manifestations of papular syphilide of the palms and soles. The effectiveness of specific treatment has been shown.

Conclusions. Doctors’ knowledge of the clinical features of syphilis against the background of HIV infection will allow them to avoid diagnostic errors leading to late treatment and the development of complications.
PERLINDUNGAN HUKUM BAGI NASABAH PADA PINJAMAN ONLINE MENURUT HUKUM EKONOMI SYARIAH
Authors: Aulia Rahmatullah
Published: April 2024

This article aims to examine the legal protection for customers in the implementation of online-based money loans or known as online loans (pinjol). The research method used is a doctrinal approach where the author will examine legal norms related to customer protection according to the Banking Law, and a number of Financial Services Authority (OJK) regulations related to pinjol. The results of this study conclude that there are several phenomena that occur in the implementation of pinjol that do not get legal protection for customers, namely: First, the determination of interest that does not refer to the interest rate provisions of Bank Indonesia, second, the maximum interest setting on online loans in fintech companies is 0.4 percent per day but the amount of real interest is not regulated in the agreement. Third, Financial Services Authority Regulation No.77/POJK.01/2016 on Information Technology-Based Money Lending and Borrowing Services OJK Regulation No.77 of 2016 is the basis for the implementation of Peer to Peer Lending business activities or online lending and borrowing which is one of the types of fintech, including the protection of customer personal data. Customer personal data collected by fintech providers must be kept confidential in accordance with applicable privacy provisions.
Prospects for the Formation of an Educational Ecosystem
Authors: Lapygin Yu. N. , Glebov G. E.
Published: April 2024

During the period of higher education reform, there is an increasing need to identify new approaches and develop the discussed models of interaction between the university and students, employers and authorities, which makes it relevant to study the prospects of university structures from the perspective of the ecosystem approach. The purpose of this study is to determine the main characteristics of the ecosystem as a socio-economic phenomenon, the projection of which onto the higher education system gives an idea of the strategically significant directions of its development. Among the research methods, content analysis of scientific publications, methods of paired comparisons and aggregation of keywords for constructing verbal models, as well as methods of logical analysis and synthesis of information within the subject area of research were used. The work identifies the main parameters of educational ecosystems in terms of prospects for the development of higher education in modern Russian conditions. As a result, an integral definition of such a concept as “ecosystem” is given, and in relation to the higher education system, the possibility of building a network structure of a university system using innovative platforms aimed at realizing synergistic effects for all participants in the educational ecosystem being formed is shown.
Specifics of Systematic Challenges Development on Highly Qualified Labor Market
Authors: Melnikova I. Yu. , Popov D. G. , Novik D.  G.
Published: April 2024

Key issues of Russian labor market transformation in the context of new challenges are discussed in this article. The authors pay special attention to the issue of perception of “high qualification” notion considering rising importance of soft skills. The authors’ approach to the solution of work force shortage issue is based on the analysis of trends in Russian labor market presented in the article and provides for two sources: retraining and reproduction of manpower on national base, and attraction of foreign specialists. The employer bears final responsibility for the professional’s work results regardless of model used to assess qualification, so the employers’ role in assessing (and more importantly developing) staff qualification should be fundamental.
Probabilistic and Statistical Approach to Evaluating the Effectiveness of Management Decisions
Authors: Toguzaev T. Kh. , Kalitskaya V. V. , Rykalina O. A. , Sabanchiev A. H.
Published: April 2024

In a number of works by domestic and foreign authors, modern methods are proposed to solve the problem of the effectiveness of decision-making and execution. Quite satisfactory results have been achieved both in theoretical, methodological and applied terms. However, this only casually mentions the effect that occurs in any, and not only an unrealized solution — the appearance of some remnants; not unrealization, but fundamental unrealizability without a remainder. The very nature of unrealizability or the presence of residual has not been considered before, although the effect of residual is constantly observed. The discrepancy between the solution and its implementation was associated with the insufficient quality of the solution or with the shortcomings of its implementation, which is considered in the context of “incomplete information” and “the presence of hidden variables/factors”. This understanding allowed the remnants themselves to be considered in several angles and aspects: a) as a residue from the implementation (“unrealized opportunities”), b) as an over-realization of realized opportunities, c) as errors in the development of solutions, d) as technical, organizational, etc. disadvantages in the implementation of the solution, etc. However, the immediate consideration of the problem of evaluating the effectiveness of decision-making indicates the presence of a fundamental unrealizability in it, which is expressed in the appearance of a remainder when it is implemented in any case. Moreover, this remainder is not associated with realizability as such and not with the solution as such, but with the presence of a special property of residuality, which is of a fundamental nature. The purpose is to identify, describe and propose a method for assessing the phenomenon associated with the incompleteness of the implementation of a management decision, regardless of its quality. A set of logical and descriptive methods was used in the study. Results: a review of situations with the appearance of residues in decisionmaking is carried out; a criterion and a method for evaluating the effectiveness of decisionmaking is proposed, a rule for the residual implementation of a decision is formulated; a justification of the proposed rule in various aspects is given; a classification of options for the unrealizability of decisions is proposed. The results obtained can be useful in making and implementing a decision.
Justification Strategic Priorities of Investment Development of the Republic of Armenia
Authors: Vlasyuk L.  I. , Yolchyan A. N.
Published: April 2024

The Republic of Armenia requires investments for economic growth and development, including foreign direct investment due to the small capacity of the domestic market. The investment strategy must be consistent with the national development strategy and must be the resource base of the national strategy in terms of realizing the values and interests of the country’s residents. The purpose of the study is to substantiate the strategic priorities of investment development of the Republic of Armenia and to identify priority development sectors that have competitive advantages and investment potential. The methodological basis of the research is the theory of strategy and methodology of strategizing by academician V. L. Kvint. According to the strategy methodology, an analysis of global investment and national trends was carried out, and successful international experience in attracting investments was studied. The experience of Israel is considered, which demonstrates a striking example of improving the investment attractiveness of the country thanks to an effective investment strategy. The strategic priorities of Israel’s investment strategy are highlighted, some of which need to be implemented in the practice of attracting investments in the Republic of Armenia. To substantiate strategic priorities and highlight highly competitive industries, regulations governing the attraction of foreign direct investment in Armenia, the economic state of Armenia were studied, and an OTWS analysis of investment activity was conducted. Based on the results of a comprehensive analysis, the authors propose two groups of strategic priorities: primary strategic priorities and auxiliary priorities that enhance the significance and effectiveness of the former. The study shows that strategic industries with competitive advantages and investment potential for Armenia are the chemical and metallurgical industries, textile and clothing industries, tourism, pharmaceuticals, and agro-industry. An effective investment strategy for the Republic of Armenia is the basis for the country’s further development.
External Factors in the National Governance Model
Authors: Khlutkov A. D.
Published: April 2024

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ESG-Ratings: Nonparametric Methods of Construction
Authors: Yurkov A. V. , Babaeva Zh. R.
Published: April 2024

Many of the largest Russian companies are evaluated by international financial institutions or rating agencies in terms of their influence on ESG factors that take into account environmental issues, interaction with society and corporate governance. Such ratings can have various names, most often referred to as ESG ratings. The inherent subjectivity of the assessments, along with the lack of generally recognized standards and transparency of the methodology, cause concern both from the assessed companies and from investors and regulators. ESG ratings of Russian rating agencies are at an early stage of their development, which is reflected in a small number of evaluated companies. The purpose of the study is to study the main methodological problems in the compilation of ESG ratings identified by the academic and business community with a focus on studying the issue of choosing weights when constructing a summary indicator. The information base of the study is the data published by the rating agency RAEX, which is positioned as the largest agency in the field of non-credit ratings. A comparative analysis of the rating agency’s weight selection methods with nonparametric methods, such as methods of shell analysis, determination of preferences based on similarity with the ideal solution and calculation of the geometric mean is carried out. Based on the results of the study of the initial data of the rating agency, it can be concluded that most companies have low ratings for the environmental component and high ratings for the corporate governance component, while none of the companies has a benchmark rating. The main methodological problem in the selection of weights is the subjective nature of the weights used by the rating agency. Correlation analysis of the studied non-parametric methods showed a high correlation with each other and with the initial ratings of the rating agency, however, at the level of some individual companies, the ratings may differ depending on the chosen method.
Cold water coral Lophelia pertusa mortality under ocean warming is associated with pathogenic bacteria
Authors: Chemel Mathilde , Peru Erwan , Binsarhan Mohammad Mutlaq , Logares Ramiro , Lartaud Franck , Galand Pierre
Published: April 2024

Cold-water corals form vast reefs that are highly valuable habitats for
diverse deep-sea communities. The deep ocean is, however, getting
warmer, and models predict that the temperature of the Atlantic Ocean
will further increase by up to 3°C by the end of the century.
Understanding the response of cold-water corals to ocean warming is
therefore essential to assess their resilience to future water
temperatures. Here, we investigate at the holobiont level, the coral
host and its associated microbiome, the effects of elevated temperatures
on the reef-forming cold-water coral Lophelia pertusa (now named
Desmophyllum pertusum) from the north east Atlantic Ocean. We show that
at temperature increases of +3 and +5°C, L. pertusa exhibits significant
mortality concomitant with changes in its microbiome. A metagenomic
approach revealed the presence of genes markers for bacterial virulence
factors suggesting that coral death was due to infection by pathogenic
bacteria. Differences in survival were observed between L. pertusa
colonies, as well as colony-specific microbiome signatures, indicating
strong colony variability between colonies in response to warming
waters. We hypothesize that L. pertusa, regardless of their ocean of
origin, can only survive a temperature increase of < 3°C over
a long period of time. Regional variations in deep-sea temperature
increase should therefore be taken into account in future estimates of
the global distribution of cold-water corals.
Montane diversification as a mechanism of speciation in Neotropical butterflies
Authors: Magaldi Luiza , Gueratto Patrícia , Ortega-Abboud Enrique , Sobral-Souza Thadeu , Joron Mathieu , Freitas André , Brandao Karina
Published: April 2024

The mountains in the Atlantic Forest domain are environments that harbor
a high biodiversity, including species adapted to colder climates that
were probably influenced by the climatic variations of the Pleistocene.
To understand the phylogeographic pattern and assess the taxonomic
boundaries between two sister montane species, a genomic study of the
butterflies Actinote mantiqueira and A. alalia (Nymphalidae: Acraeini)
was conducted. Analyses based on the COI barcode region failed to
recover any phylogenetic or genetic structure discriminating the two
species or sampling localities. However, SNPs gathered using GBS
provided a strong isolation pattern in all analyses (genetic distance,
phylogenetic hypothesis, clustering analyses, and FST statistics) that
is consistent with morphology, separating all individuals of A. alalia
from all populations of A. mantiqueira. The three sampled mountain
ranges where A. mantiqueira populations occur — Serra do Mar, Serra da
Mantiqueira, and Poços de Caldas Plateau — were identified as three
isolated clusters. Paleoclimate simulations indicate that both species’
distributions changed according to climatic oscillations in the
Pleistocene period, with the two species potentially occurring in areas
of lower altitude during glacial periods when compared to the
interglacial periods (as the present). Besides, a potential path between
their distribution through the Serra do Mar Mountain range was inferred.
Therefore, the Pleistocene climatic fluctuation had a significant impact
on the speciation process between A. alalia and A. mantiqueira, which
was brought on by isolation at different mountain summits during
interglacial periods, as shown by the modeled historical distribution
and the observed genetic structure.
Manuscript title: Activating invasion and metastasis in small cell lung cancer
Authors: He Carl
Published: April 2024

Background: Small cell lung cancer (SCLC) harbours the most
aggressive phenotype of all lung cancers to correlate with its bleak
prognosis. The aggression of SCLC is partially attributable to its
strong metastatic tendencies. The biological processes facilitating the
metastasis in SCLC are still poorly understood and garnering a deeper
understanding of these processes may enable the exploration of
additional targets against this cancer hallmark in the treatment of
SCLC. Recent findings: This narrative review will discuss the
proposed molecular mechanisms by which the cancer hallmark of activating
invasion and metastasis is featured in SCLC through important steps of
the metastatic pathway. The review will discuss SCLC VEGF family
expression and vascular mimicry as a means of vasculogenesis, and the
role of tumour heterogeneity, DLL3, NFIB, selectin, and B1 integrin in
enabling epithelial to mesenchymal transition and subsequent invasion,
and the molecular markers expressed by SCLC to assist organ-specific
homing during metastasis. The review will also discuss a recent article
observing mir-1 mrna upregulation as a potential therapeutic option in
targeting the metastatic activity of SCLC. Conclusion:
Treatment of SCLC remains a clinical challenge due to its recalcitrant
and aggressive nature. Amongst the many hallmarks used by SCLC to enable
its aggressive behaviour, that of its ability to invade surrounding
tissue and metastasise is particularly notable and understanding the
molecular mechanisms in SCLC metastasis can identify therapeutic targets
to attenuate SCLC aggression and improve mortality.
Planning Safe Navigation Routes in the Seas of Arctic Shelf Based on Deep Learning Algorithms
Authors:   Oil and Gas Research Institute of the Russian Academy of Sciences, Eremin N.A. , Guliev R.Z. ,   Federal University named after M.V. Lomonosov, Vyatkin D.A. ,   Federal University named after M.V. Lomonosov, Ivanitskaya E.V. ,   STC «Industrial Safety» CJSC
Published: April 2024

A comparative analysis of interannual changes in the ice coverage of the Pechora and the Kara Seas has been conducted based on the information of open sources (satellite observations) gathered by the Arctic and Antarctic Research Institute and the open dataset with mapped ice conditions ArcticDEM. The following problems of the study have been solved: the analysis of the most common approaches to building a forecast based on the analysis of ice conditions has been conducted; a deep learning algorithm to solve the problem of analysis of ice fields has been developed and tested; a medium-term forecast of the condition of ice fields in the area of the Pechora and the Kara Seas has been prepared based on the approbation model example; the obtained results have been analyzed and processed. In the course of study, an algorithm of automated mapping of ice conditions based on the satellite imagery data has been developed; the possibilities of its application to forecast ice conditions automatically, i.e., without using a manmade mapping, have been described. It has been demonstrated that the use of images based on multiple spectral bands and the combination of data from different satellites can minimize the influence of clouds and weather conditions. The model gave the real forecasting accuracy for a period of 10–14 weeks equal to 49–53 % for the Barents (Pechora) and the Kara Seas of 2018–2021. In case the model was fine-tuned and included data from the Barents (Pechora) and Kara Seas before 2018 in the training sample, the accuracy on the data after 2018 increased up to 52–56 %. The feature of the model is its ability to operate with different classes of ice and precisely determine its amount. The developed method increases the efficiency of operational control over the ice conditions in the Arctic seas. Safe navigation routes for shipping transport in the Pechora Sea have been modeled.
Improving the Occupational Risk Management Methodology
Authors:   Don State Technical University, Samchuk-Khabarova N.Ya. , Gaponov V.L. ,   Don State Technical University
Published: April 2024

The issue of occupational safety improving methods has been considered based on the example of a single enterprise. The area of improvement of activities a priori aiming at occupational safety has been chosen. In particular, the optimization of risk management stages at the workplace has been proposed. A risk management methodology consisting of standard stages (identification, assessment, management) but including separate improved levels or elements has been developed. A set of tables for volumetric, qualitative, and quantitative identification of hazards enabling the reduction of the number of unaccounted risks at the workplace has been formed. For the risk assessment stage, the application of an increasing human factor coefficient that reflects the individual characteristics of an employee affecting risk levels at the workplace has been proposed. For the relevant cases, it is recommended to use the machinery equipment assessment model to detect more risks at the workplace equipped with a machine. The occupational risk management stage has been improved due to differentiated and clarified formulations of hazards, which allows for choosing a correct and efficient measure. The methodology is also supplemented with a set aiming at occupational and industrial stress. For the identification stage, a set of parameters has been selected to determine psychosocial risks. The risk management process has been improved in the part of stress factors. In order to substantiate the performance and efficiency of the improved methodology as compared with the methodology applied at the enterprise, a comparative analysis of the two methodologies has been conducted at 10 different workplaces. The data confirming the increase of performance and efficiency of the improved methodology has been provided, which logically, on the condition of the consistent implementation of all occupational risk management stages, will reduce risks at the workplace and the number of industrial injuries, and ensure increased occupational safety.
Огнетушащие смеси дибромметана с фторированными алканами для пожаро- и взрывозащиты объектов нефтегазового комплекса
Authors:   FGBU VNIIPO EMERCOM of Russia, Kopylov P.S. , Agafonov V.V. ,   FGBU VNIIPO EMERCOM of Russia, Kopylov S.N. ,   FGBU VNIIPO EMERCOM of Russia, Golov N.V. ,   FGBU VNIIPO EMERCOM of Russia
Published: April 2024

The high fire hazard level is specific to the oil and gas industry due to the circulation of large volumes of flammable gases and liquids. To ensure fire protection at the oil and gas industry facilities, automated gaseous fire extinguishing is widely used. The main fire-extinguishing agents in automated gaseous fire-extinguishing systems are refrigerants HFC 23, 125, 227еа, FC 318c, and fluorinated ketone FK 5-1-12. Upon the adoption of the international agreements on combating global warming, most fluorinated gaseous fire-extinguishing agents currently used for fire extinguishing fell under restrictions. The article indicates the importance of refrigerants HFC 23, 125, 227еа, and FC 318c, whose production volume must be reduced by 85 % by 2036 to ensure the required level of fire and explosion protection of oil and gas industry facilities. A method to reduce the volumes of used fluorinated alkanes by producing highly efficient fire-extinguishing mixtures, one of the components of which is an agent of high global warming potential (GWP) and the other is a chemical compound with a short atmospheric lifetime, has been proposed. Dibromomethane, which fully meets the latest environmental requirements, is to be considered a short-lived component. Based on the well-known kinetic data, the rates of elementary chemical reactions generated in the flame of the methane-oxygen mixture when contacting with refrigerants HFC 23, 227еа, and dibromomethane, have been calculated and compared. The efficiency of using dibromomethane to increase the fire-extinguishing efficiency of refrigerants HFC 23 and 227еа has been substantiated. An experimental determination of the minimum fire-extinguishing efficiency of the generated mixed compositions is conducted to confirm the correctness of theoretical calculations. The obtained mixed gaseous fire-extinguishing agents enable the reduction of the volume of high global warming potential refrigerants by 1.5–2 times. It has been also demonstrated that the obtained mixed compositions have no toxic impact on a human.
The Methods to Improve the Efficiency of Occupational Safety Management Systems
Authors:   Moscow Aviation Institute, Galkina E.E. , Sorokin A.E. ,   Moscow Aviation Institute, Daynov M.I. ,   Moscow Aviation Institute, Golovanova Т.V. ,   Moscow Aviation Institute, Kovtun M.A. ,   Moscow Aviation Institute
Published: April 2024

The high level of occupational injuries has been registered globally. Daily, 5,000 deaths are caused by industrial accidents and occupational illnesses. It is an issue that requires an urgent solution. The International Organization of Standardization has developed the ISO 45001:2018 Standard; implementing its recommendations in the working practices of an enterprise should increase the efficiency of activities aiming to ensure occupational safety. The basic recommendation of the standard is the development of an occupational safety management system at the enterprise. It is a documented system; within its setup, it is required to develop a significant volume of documentation and determine information links between the departments. The enterprise, however, must not focus only on documentation. The main functioning efficiency factor of the occupational safety management system is training for staff. Conditions to boost staff activities and their involvement in the development of favorable working conditions, detection and elimination of hazards at the workplace must be provided. An essential factor of the successful functioning of the occupational safety management system is the conducting of recurrent audits (1–2 times a year) at each department of the enterprise. Nevertheless, hazards and incidents at the workplace can emerge daily; therefore, the staff should act as auditors as the efficiency of detection of emerging hazards and risks and their timely elimination will depend on the staff’s qualification, attention, and active approach. In order to boost staff involvement, constant improvement of competencies and the use of an incentive system developed considering the efficiency of proposals on occupational safety improvements can be recommended. The involvement of staff in occupational safety activities, their understanding of the importance of such activities aiming at the safety of life and health, and the support of initiatives of the staff are possible on the condition of interest of the enterprise's top management in the efficient measures to ensure occupational safety. Involvement of all employees of the enterprise in solving occupational safety problems will enable significant improvement of working conditions, reduce the level of occupational injuries, and resolve social issues within the framework of achievement the goals of the sustainable development program.
Location of Personnel in Coalmine Excavations — Reality and Myths
Authors:   OOO NPF «Granch», Novikov A.V. , Panevnikov K.V. ,   OOO NPF «Granch», Pisarev I.V. ,   OOO NPF «Granch»
Published: April 2024

The study considers the systems of location of workers in coalmine excavations; the application of such systems is regulated by the Safety rules in coalmines. It has been shown that in Russian coalmines, zonal-type systems and continuous systems are operated. The compliance of each type of system with the requirements of the Safety rules in terms of design, functionality, and technical parameters has been assessed. The features of building a zonal-type system as to the methodology of placing tag readers in excavations have been determined. The continuous system functionality has been analyzed. It has been shown that in addition to the main function of personnel’s location, the system acquires other useful properties, i.e., the use of gas analyzers installed in the headlamp to transmit measurements in real-time mode indicating a measurement location; the implementation of two-way voice communication between a mining dispatcher and workers in excavations via individual headlamps. By the results of the study, the concluding provisions have been formulated: in zonal-type location systems, it is possible to meet the regulatory requirement for a five-second data update period on the condition that the maximum distance between readers does not exceed 60 meters; in continuous personnel’s location systems, due to their design features, additional functions to ensure industrial safety and organizational properties are implemented, expanding the practical value of such devices.
Rhizobox Technology for Sustainable Agriculture–Acquired Implications
Authors: Miah Md. Yunus , Rubaida Nusrat Jahan , Kamal Mohammed Zia Uddin , Kabir Md. Humayun , Salam Mohammed Abdus , Fujiwara Toru , Wang Ming Kwang , Imberger Karl
Published: April 2024

Evaluation on the effect of rhizobox technology in the rhizosphre soil of agricultural crops is necessary for sound and safe agriculture. This article confers the rhizobox technology-induced information about rhizosphere so far conducted since 1987s and on. Combined with its special features and construction technique, rhizobox-affected rhizosphere processes like pH changes, patterns of nutrient distribution, heavy metal movement and microbial activities are extensively analyzed. Finally, the established rhizobox model of 1987 encompassing its modified versions are detailed, followed by its potential application in rhizosphere studies of plant nutrition, soil chemistry, and soil biology for sustainable agriculture.
THE PENALTY FUNKCIONS METHOD AND OPTIMALITY CONDITONS
Authors: KHACHATRYAN RAFIK , STEPANIAN SEYRAN
Published: April 2024

The presented work is devoted to one of the most important areas of applied mathematics, namely mathematical programming.
The following general mathematical programming problem is considered where   are Lipschitz, and  is closed set.
The purpose of the work is to obtain optimality conditions for the problem posed using the method of penalty functions.
The obtained necessary conditions are expressed in the language of subdifferentials, which are a generalization of the method of indefinite Lagrange coefficients for nonsmooth optimization problems.
PHYSICAL INTERPRETATION OF PARAMETRIC RESONANCE BY ENERGY APPROACH
Authors: PETROSYAN LERNIK , ELOYAN GAREGIN
Published: April 2024

The object of study is the phenomenon of parametric resonance from the point of view of physical interpretation.
             The purpose of the study is to identify one of the special cases of the phenomenon of parametric resonance associated with an oscillating reference frame, when the parametric system contains time-dependent capacitive and inductive reactance.
Based on physical measurements using a simple mathematical apparatus, qualitative analyzes are given that combine the harmony of mathematical and physical approaches.
Parametric resonance is an extremely complex phenomenon associated with the imbalance of linear systems. Therefore, disequilibrium occurs due to small accumulations in an infinite time interval. Like small clusters, infinite time intervals are not suitable for graphical representation and physical interpretation of resonance. For this reason, the study of parametric resonance leads to formal mathematical problems that are idealized and difficulties arise when comparing them with practical ones.
Theoretical methods, analyzing professional literature, also a quantitative analysis of the obtained results are used.
In the radio-physical literature, insufficient attention is paid to the study of two non-stationary reactivity, although the possibilities of using a parametric circuit can be significantly expanded. The article analyzes this problem, since it was solved exclusively by physical methods.
IDEOLOGICAL TENDENCIES OF DISSENT IN SOVIET ARMENIA IN THE 1960S AND 1980S
Authors: HARUTYUNIAN SHAHEN
Published: April 2024

There were three primary ideological paths followed by the dissident movements in Soviet Armenia that originated in the USSR in the 1960s of the 20th century. In Soviet Armenia, dissent was primarily organized around national issues such as the mention of the Armenian Genocide, the demands for the reunification of Karabakh and Nakhichevan to the motherland, preservation of the Armenian language, restoration of Armenia's independence, and defense of human rights. Objectives and plans of covert groups established in Soviet Armenia bore the ideological imprint of these movements. The fight to restore Armenia's independence was of utmost significance in Soviet Armenia.
The purpose of this article is to present the ideological directions of Armenian dissent and their manifestations.
In order to realize the goal, the task was set to research and discuss the dissident organizations founded in Soviet Armenia and the individual approaches that integrated all the ideological directions of the Armenian dissident in their programs and activities.
Historical and comparative methods were used.  Content analysis of state and personal archival materials, interviews, and memoirs was carried out.
It has been established that the dissident manifestations in Soviet Armenia had three key ideological directions, which had different priorities in different periods.
MAIN CAUSES AND CONSEQUENCES OF LABOR MIGRATION OF YOUTH
Authors: SHAHINYAN ANDRANIK
Published: April 2024

16-30 years old young citizens of the Republic of Armenia, who applies for the labor migration, are the object for the research of the article.
The main goal of the research is to study the causes of the labor migration of young people and its demographic, socio-economic, educational consequences, as well as to receive objective, unbiased and as reliable as possible expert assessments regarding external migration movements for the period of 2021-2023.
The main results of the research are the eloquent witness of the fact, that the main reasons for the migration trend of young people in the Republic of Armenia are due to the low levels of the salaries, high levels of poverty, the ongoing alarming military situations and with complaints from the public education sector.
As a  conclusion, we consider, that it is necessary to emphasize in the revised the none correct, and in some cases, the absense of organizing youth employment. And this causes the apply of many young people (both men and women) for labor migration.
Optimizing Droplet Digital PCR Assay for Precise Assessment of MEIS1 Gene Promoter Methylation
Authors: Marek Samec , Ivana Baranova , Iryna Zavhorodnia , Martin Pec , Renata Pecova , Vincent Lucansky
Published: April 2024

DNA methylation is characterized as a gene regulatory mechanism that involves the methylation of the 5-carbon (C5) position of cytosine, resulting in the formation of 5-methylcytosine. The analysis of aberrantly methylated cytosine-phosphate-guanine (CpG) dinucleotides, primarily in the promoter regions of tumor suppressor genes, can serve as promising prognostic and predictive markers of cancer development. Meis homeobox 1 (MEIS1) gene, crucial for cell growth and differentiation, exhibits dysregulation linked to various cancer types, acting as both a positive and negative regulator. The selection of an appropriate method for the evaluation of gene promoter methylation status is important for clinical implementation without biases regarding false positive and false negative outcomes. The study focuses on the optimization of a novel droplet digital PCR (ddPCR) assay for identifying the methylation status of MEIS1. Compared to traditional methods, ddPCR offers an increased sensitivity and specificity, presenting a promising tool for precise DNA methylation assessment with potential implications for cancer diagnostics and prognostics.
Research on Legal Education at Jinan University During the Shanghai Period (1927-1932)
Authors: Chen Min , Yu Xinye
Published: April 2024

In the autumn of 1927, Zheng Hongnian appointed Shi Jiong as a professor and established the Department of Law, setting the educational goal of “cultivating useful judicial talents for national service and national glory”. He actively pursued legal education and pioneered a specialized course in Diplomatic Consular Affairs. The legal systems of the countries where overseas Chinese from Nanyang resided were predominantly based on the “Anglo-American Law” system. The “Anglo-American Law” education at Jinan University was distinctively emphasized, and the continuous refinement of the “Six Law” system led to a shift towards a “Comparative Law” model. As Jinan University’s legal education was flourishing, it faced dual calamities of war and educational crises, ultimately leading to its closure.
Construction of Traditional Village Health Development Evaluation System Based on Ecological and Cultural Health Theory
Authors: Pang Chunyu , Lu Min
Published: April 2024

Traditional villages, as spatial carriers with rich cultural resources, are important cornerstones for cultural inheritance and promotion, and their ecological and cultural symbiosis has been formed in the process of long historical development, which contains rich ecological wisdom. To comprehensively analyze the development status of traditional villages and plan and design future development, this study is guided by the theory of ecological and cultural health, selects the evaluation elements of the target level, criterion level, and indicator level, and devotes itself to constructing an evaluation system of the healthy development of traditional villages, and applies the hierarchical analysis method and the entropy weight method to determine the index weight, to establish a comprehensive evaluation model of the healthy development of traditional villages. By evaluating the healthy development of traditional villages in Ning’an City, Mudanjiang City, and Heilongjiang Province, the study verifies the feasibility of the evaluation system constructed by the study for the healthy development of traditional villages. It proposes corresponding healthy development strategies for the evaluation analysis to provide reference ideas for traditional villages’ ecological and cultural health and sustainable development.
Factors and Mechanisms Influencing Consumers’ Willingness to Participate in Food Safety Social Co-governance: An Empirical Study from China
Authors: Zhang Chunsheng , Ji Mingxin , Deng Zhaoyan , Wu Di
Published: April 2024

Food safety governance and its performance improvement are inseparable from the cooperation of multiple subjects. The extensive participation of consumers is not only a powerful supplement to the deficiency of supervision resources but also an intrinsic request for seeking both temporary and permanent solutions to food safety problems. To ascertain the factors and mechanisms that influence consumers’ participation willingness of food safety social co-governance, an integrated conceptual model was constructed based on the Theory of Planned Behavior (TPB) and Benefit-Risk Analysis (BRA). 664 valid questionnaires collected in China were used to verify the hypotheses with the application of the Structural Equation Model (SEM). The results showed that behavior attitude, subjective norm, and perceived behavior control significantly impacted consumers’ participation willingness, and the influence strength was in the sequence of perceived behavior control, behavior attitude, and subjective norm. Perceived risk and participation willingness showed a strong negative relationship. Besides that, perceived risk also played a partial mediation role in predicting behavior attitudes toward consumers’ participation willingness. According to the conclusions, a series of policy suggestions were also proposed to help improve consumers’ participation willingness.
Analysis of the Yellow River water and sediment monitoring data
Authors: Liu Wenbin , Liu Dongbing
Published: April 2024

Graphics are drawn about the sediment content, water flow, and water level of the Yellow River with time. A cluster scatter plot of sand content is made with changes over time. Using variance analysis of a factor, it is concluded that sediment content is affected by two variables month and year. By studying the changing pattern of water-sand flux, the timing diagram of the water and sediment flux of the Yellow River with time is drawn. The flux of water and sand is predicted for the next two years. According to the prediction results, the optimal sampling and monitoring scheme is developed.
Investigation on Wind-Induced Structural Damage and Preventive Measures of Low-Rise Buildings in Coastal Areas
Authors: Zhang Maoyu , Tian Shengbao , Wang Yanru , Fu Bin , Zhang Chuanxiong , Zheng Shuqin , Jiang Ruinian
Published: April 2024

Strong winds, typhoons, and other extreme weather can cause significant damage to house structures, resulting in great harm to human life and property safety. It is imperative to prepare and strengthen infrastructure against these extreme weather conditions to minimize their impact. This paper conducts an on-site survey of low-rise houses in Cangnan County and Dongtou District, located on the south coast of Zhejiang, affected by typhoons. It summarizes the structural characteristics of houses and the damage caused by typhoons to house structures. The paper also performs a preliminary analysis of the damage mechanism of houses. Additionally, it examines wind-resistant measures used by the private sector, identifies potential issues with wind-resistant design, and proposes corresponding wind-resistant countermeasures and recommendations for low-rise houses. The research presented in this paper can be utilized for analyzing the wind damage mechanisms of low-rise houses in the future. Moreover, it offers a valuable reference for the analysis and simulation of wind damage in low-rise houses in typhoon-prone coastal areas. This research holds significant value in preventing wind damage to low-rise houses.
Impact Assessment of Large-scale Sports Events on Tourism: A Case Study of the 16th Asian Games
Authors: Yan Yanrong , Liu Chengqun
Published: April 2024

The positive impact of hosting large-scale sports events on tourism is examined in this study, focusing on the 16th Asian Games as the research subject. The Difference-in-Difference Method and Synthetic Control Method are employed to analyze the event’s influence on tourism in Guangzhou and other cities within Guangdong Province. The findings demonstrate a significant driving effect of such events on the growth of tourism in host cities over subsequent years. Moreover, it is revealed that the 16th Asian Games has a particularly pronounced impact on remote cities located far from Guangzhou, including those situated in the eastern, western, and northern regions of Guangdong Province. Consequently, this study suggests that host cities should seize opportunities by engaging in scientific planning and meticulous arrangements for large-scale events. Additionally, other cities within the province where these events take place should actively participate in enhancing their ability to serve such occasions while improving both the level and quality of their tourism services. This approach will enable them to capitalize effectively on hosting opportunities and facilitate high-quality development across all parts of the province.
Comparative Study on Flight Training of Chinese Airline Pilots at Home and Abroad
Authors: Zhu Shouxi , Chen Jian
Published: April 2024

The study aimed to analyze flight training methods for Chinese airline pilots, comparing domestic and foreign approaches while assessing their respective advantages and disadvantages. Various aspects including language, culture, airspace, flight support, teaching methods, training standards, and costs were examined. Additionally, a quantitative analysis was conducted on theory and practical exam results, as well as the personality development of cadets from both training backgrounds. Results revealed that foreign flight training offered several benefits over domestic training, such as shorter duration and lower costs due to airspace accessibility. Cadets undergoing foreign training demonstrated higher average scores and passing rates in Instrument Rating and Commercial License Examinations compared to domestically trained counterparts. Furthermore, foreign training positively influenced cadets’ personality development. In conclusion, foreign flight training demonstrated significant advantages in terms of overall cost-effectiveness, training quality, and cadet professionalism. However, domestic training also had its merits. Thus, the authors recommended a comprehensive evaluation to determine the most suitable training approach for individual cadets.