bluuebunny/crossref_metadata_2025 huggingface dataset:
A new species of Tupaia (Mammalia, Scandentia, Tupaiidae) from northeastern Vietnam
Authors: Ly Ngoc Tu , Vu Thuy Duong , Dang Huy Phuong , Nguyen Dinh Duy , Le Duc Minh , Nguyen Thi Tham , Bui Tuan Hai , Oshida Tatsuo , Endo Hideki , Masaharu Motokawa , Nguyen Kim Thuy , Nguyen Truong Son
Published: October 2022

There are 19 currently recognized species of treeshrews in the genus Tupaia (Tupaiidae, Scandentia) with a majority of the taxa found in Southeast Asia. During our surveys in northeastern Vietnam, nine new specimens of Tupaia were collected from five different localities, including Lang Son and Ha Giang provinces and Cat Ba Island, Hai Phong City. Our molecular analysis reveals that the new population diverges from its closest congeners by at least 11.2% based on a fragment of the mitochondrial COI gene and 10.1% based on a fragment of the mitochondrial cytochrome b (Cyt b) gene. The distinction of the newly discovered population is also supported by significant differences compared to other species based on morphological analysis. As a result, a new species, Tupaia danghuyhuynhi sp. nov., was described based on morphological and molecular evidence.
Pandémie de Covid-19 : contribution de la métrologie à l’évaluation de l’efficacité de filtration des masques de protection
Authors: Gaie-Levrel François , Bescond Alexandre , Fouqueau Axel , Macé Tatiana , Vaslin-Reimann Sophie
Published: October 2022

En 2020, la communauté scientifique et l’Organisation mondiale de la santé confirmaient le risque de transmission aérienne du coronavirus Sars-CoV-2. En raison de la pénurie mondiale de masques, plusieurs pays ont introduit de nouveaux types de protection. Dans ce contexte, la Commission européenne a identifié le besoin urgent d’harmoniser les exigences en la matière, notamment en termes de performances de filtration et de confort associées au port du masque. Un guide de l’Afnor et un guide européen CEN ont alors été élaborés ; et, en lien avec les demandes des pouvoirs publics français formulées pendant le premier confinement, en 2020, le LNE a été mobilisé afin de répondre à la question centrale de l’efficacité des masques de protection apportant en la matière toute son expertise en métrologie des aérosols. Pour ce faire, une plateforme expérimentale a été développée en un temps record pour évaluer l’efficacité de filtration de différents types de masques de protection. Ce nouveau moyen d’essai permet, depuis le début de la crise, d’accompagner les pouvoirs publics, les industriels et les importateurs dans la qualification des masques FFP2, chirurgicaux, barrières et grand public. Dans cet article, nous présentons le banc expérimental développé par le LNE pour réaliser les mesures d’efficacité de filtration des masques barrières et grand public, ainsi que les comparaisons inter-laboratoires organisées dans ce cadre. En termes de perspectives, des axes d’amélioration du contexte normatif associé à chaque type de masques sont également présentés.
Crise de la Covid-19 : les professionnels des établissements de santé en souffrance
Authors: Fournier Alicia , Haliday Héloïse , Binquet Christine , Quenot Jean-Pierre , Laurent Alexandra
Published: October 2022

Alors que l’infection au Sars-CoV-2 s’est rapidement propagée au niveau mondial, on a assisté à une mobilisation massive des établissements de santé pour accueillir l’afflux important de patients. La majorité des recherches ayant étudié l’impact psychologique de la crise sanitaire dans les établissements de santé se sont centrées sur les professionnels de première ligne. Mais, dans les faits, c’est l’ensemble des professionnels qui ont été affectés. Dans cet article, nous proposons d’effectuer une mise au point sur le vécu de ces professionnels dans les établissements de santé durant les premiers mois de la crise de la Covid-19. L’objectif de notre étude était d’identifier les facteurs de stress spécifiques, mais aussi communs à chacune des professions, en nous basant sur le discours de ces professionnels.
Troubles chimiosensoriels causés par la Covid-19 : effets à long terme et piste d’une solution
Authors: Zigrand Coline , Brosse Sarah , Bouguiyoud Nouhaila , Bérubé Simon , Bussière Nicholas , Frasnelli Johannes
Published: October 2022

Les symptômes de la Covid-19 tels que la toux, la fièvre et l’essoufflement se résorbent généralement quelques jours après l’infection. Une récente étude de notre laboratoire de recherche en neuroanatomie chimiosensorielle (Québec, Canada) a investigué les effets à long terme de la Covid-19 sur les sens chimiques (odorat, goût et système trigéminal). Nos résultats soulignent qu’environ un an après avoir été infectés par la Covid-19, les participants rapportent encore souffrir de troubles chimiosensoriels.
Organisation et monitoring des capacités hospitalières en période de crise
Authors: Garaix Thierry , Breen Camille , Messabis Mohamed El Habib , Phan Raksmey
Published: October 2022

Le présent travail scientifique propose un outil d’aide à la décision pour accompagner la gestion stratégique de la capacité hospitalière en situation de crise similaire à celle de la Covid-19. Cette pandémie a mis en évidence le manque de préparation des systèmes de santé du monde entier, dont le système de santé français. En suivant les projections de l’évolution de la pandémie tout au long d’un horizon temporel déterminé, il s’agit pour nous de proposer une politique d’activation et de désactivation dynamique des ressources exceptionnelles dégagées par les établissements de santé pour prendre en charge le flux massif de patients généré par la crise. Définir une politique de gestion paraît inéluctable pour éviter toute surchauffe du système et une pause trop longue dans les activités médicales non liées à la crise sanitaire en cours, car les organisations hospitalières ont besoin de planifier à l’avance leurs déploiements importants de capacités. Ces travaux s’appuient sur des prévisions épidémiologiques et a su tenir compte du niveau de confiance accordé à ces prévisions. Nous avons focalisé notre étude sur les lits ouverts en réanimation qui exigent de mobiliser toute une série de ressources à aligner sur les capacités disponibles.
La Covid-19 et ses impacts psychologiques
Authors: Vancappel Alexis , Jansen Eline , El-Hage Wissam
Published: October 2022

Dans cet article, nous abordons l’impact psychologique de la pandémie de Covid-19. Cette pandémie a en effet entraîné un bouleversement de nos modes de vie depuis le 11 mars 2020. Pour limiter la circulation du virus, tous les gouvernements ont pris diverses mesures de confinement avec, de facto , des conséquences individuelles, sociales, culturelles, économiques, environnementales… et psychologiques. Ces changements ont entraîné une perturbation de la santé mentale au sein de la population générale, et plus particulièrement auprès de certaines catégories de la population : les enfants, les adolescents, les étudiants, les professionnels de santé et les patients souffrant de troubles psychiatriques. Nous avons ainsi observé dans ces groupes de personnes une augmentation significative des symptômes anxieux, des symptômes thymiques et des idéations suicidaires.
La surveillance épidémiologique comme outil de la gouvernance des risques : le cas de la Covid-19
Authors: Hadna Saliha
Published: October 2022

En France, depuis deux ans, les médias ne cessent de diffuser les chiffres des contaminations et des décès liés à la Covid-19, produisant un effet paradoxal en suscitant la crainte, tout en rendant ces drames singuliers (Pujol et al ., 2020). Une surveillance épidémiologique a été mise en place par Santé publique France (SPF), dès mars 2020. Les mesures gouvernementales qui se sont appuyées sur ces chiffres ont fait l’objet de nombreuses critiques (Mucchielli et al ., 2020), voire d’une défiance (Idelson, 2021). L’urgence a placé au second plan un problème majeur : l’évolution des maladies chroniques (Jornayvaz et Wojtusciszyn, 2021), notamment du cancer. Or, certains cancers, comme celui du pancréas, ont eu un taux d’incidence en hausse entre 2010 et 2018, le cancer restant la première cause de mortalité en France. Dans cet article, nous nous intéresserons d’abord au dispositif de surveillance épidémiologique de SPF. Nous analyserons ensuite la manière dont les experts ont été mobilisés lors de cette crise sanitaire. Enfin, nous montrerons que cette gestion de crise a été construite sur une approche court-termiste, dans la mesure où la déprogrammation des opérations jugées « non urgentes » pour donner la priorité aux soins Covid-19 par rapport aux soins liés au cancer n’a pas permis d’anticiper la prochaine vague de surmortalité par cancer pourtant annoncée par plusieurs études médicales.
Vivre le décès d’un proche en temps de pandémie
Authors: Verdon Chantal , Grenier Josée , Cherblanc Jacques , Simard Chantale , Bergeron-Leclerc Christiane , Maltais Danielle , Zech Emmanuelle , Cadell Susan
Published: October 2022

La pandémie suscite de nombreux questionnements liés au phénomène du deuil, où les circonstances entourant le décès d’un proche sont une source de connaissances extrêmement importantes et inédites permettant de mieux saisir l’importance des événements entourant un tel malheur. Une étude québécoise s’est intéressée à l’expérience de personnes ayant perdu un proche pendant la pandémie. Trois thèmes émergent de cette étude qui s’appuie sur des données qualitatives : le temps laissé ; le sens donné à cette épreuve ; et l’attitude du personnel soignant. L’étude livre des témoignages sur ce qui peut influencer les trajectoires du mourir et du deuil. De ces circonstances chaotiques et imprévisibles, les personnes endeuillées peuvent quand même y donner un sens quand elles peuvent poser des actes concrets : faire leurs adieux ; voir une dernière fois le défunt ; procéder à des rituels significatifs et recevoir une attention empreinte d’humanisme.
Efficient state estimation strategies for stochastic optimal control of financial risk problems
Authors: Lim Yue Yuin , Kek Sie Long , Teo Kok Lay
Published: October 2022

In this paper, a financial risk model, which is formulated from the risk management process of financial markets, is studied. By considering the presence of Gaussian white noise, the financial risk model is reformulated as a stochastic optimal control problem. On this basis, two efficient computational approaches for state estimation, which are the extended Kalman filter (EKF) and unscented Kalman filter (UKF) approaches, are applied. Later, based on the state estimate given by the EKF and UKF approaches, a linear feedback control policy is designed from the stationary condition. For illustration, some parameter values and the initial conditions of the financial risk model are used for the simulation of the stochastic optimal control problem. From the results, it is noticed that the UKF algorithm provides a better state estimate with a smaller value of the sum of squared errors (SSE) as compared to the SSE given by the EKF algorithm. Thus, the estimated output trajectory has a high accuracy that is close to the real output. Moreover, the control effort assists in estimating the state dynamics at the minimum cost. In conclusion, the efficiency of the computational approaches for optimal control of the financial risk model has been well presented.
“Channels of Interference”: Maurice Blanchot and Emil Cioran
Authors: Ionescu Arleen
Published: October 2022

Drawing on the concept of “literary interference” developed by the pioneer of polysystem theory, Itamar Even-Zohar, and expanded by other scholars, as well as on various interpretations of intertextuality, this article compares two twentieth century thinkers: the French writer, philosopher, and literary theorist Maurice Blanchot and the Romanian-born French essayist and philosopher Emil (E. M.) Cioran. The article uses Even-Zohar’s notion of “channel of interference,” and presents three such “channels” and their results that shed light on the relationship between Blanchot’s and Cioran’s works. The first “channel of interference” that I have termed the “change of epoch,” borrowing a phrase from Blanchot, led to their choice of fragmentary writing. The second, existentialism, might be able to bring their works together, especially through the way they treat the subject of suicide, focussing on Blanchot’s The Space of Literature and Cioran’s On the Heights of Despair. Finally, through the third “channel of interference,” the two thinkers’ scepticism, the article explores their engagement with the concepts of passion/passivity/patience.
Challenges in VANET
Authors: Anand S. Vijay , B. Sathis Kumar
Published: October 2022

The vehicular ad-hoc network (VANET) is a wide and rapidly developing field of vehicular communication technology study. A VANET is a network with no infrastructure. It is used to improve safety in terms of applications and convenience of use while driving. VANET is a vehicle-to-vehicle network that allows automobiles to share secure data while travelling on highways or roads. VANET applications are being developed for cities throughout the world. VANET delivers an identity recognition technology that has a significant impact on improving activity administrations and reducing traffic accidents. The main purpose of this technology is to create a safe and secure environment for vehicles. Many architectures, algorithms, and protocols have been developed and implemented in recent years to improve the performance of automobiles while travelling. The writers of this research study highlight recent issues such as developments, exploitation, safety, and security issues, as well as the most recent plans that have been run in various situations.
Real-Time Traffic Simulation of Vehicular Ad hoc Networks
Authors: T. S. Pradeep Kumar , P. Vetrivelan
Published: October 2022

Vehicular ad hoc networks (VANETs) are a type of ad hoc networks where the node movements are high and there will be instant communication between the vehicles (nodes). In this chapter, the authors propose a real-time simulation of vehicular ad hoc networks using simulation of urban mobility (SUMO) in two cases: 1) user-defined road structure and 2) roads designed through open street maps. In both these cases, cars, buses, trucks, pedestrians, and bicycles will be running in the roads. Most of the vehicles will be following the Euro emission norms. Later these cars will be modelled as nodes in a network and analyse the various network performance metrics like throughput and packet delivery ratio were computed.
Capacities of Restorative Practices Within Domestic Customs and Traditions
Authors: Asli Mehrdad Rayejian
Published: October 2022

Despite the recognition of the concept of 'restorative justice' in the Persian literature of criminal sciences during recent decades, Iran has a long history of traditional customs and heritages with restorative function that their origins could be found in both pre-Islamic and post-Islamic historical eras. However, the restorative practices have entailed contradictory outcomes of reception and censure. The sympathizers believe that they are a specific means for interaction and relations between tribes, clans, and ethnic groups, or mechanisms of social control. But the opponents criticize such practices due to their potential detrimental consequences particularly in some cases of forced marriage. Notwithstanding these considerations and concerns, one approach to this issue alongside the subject of the present book is to inquire the capacities of restorative practices within domestic customs and traditions of Iranian society. In addition, the legislative manifestations of restorative practices within the Iranian legal system and challenges of the related legislation deserve to be discussed.
Accessibility of Thermal Hotels for Disabled and Elderly Tourists
Authors: Zorlu Özcan , Baytok Ahmet , Avan Ali
Published: October 2022

This study explores how thermal hotels are considering the accessibility of facilities and adjustments for disabled and elderly tourists during service production. Within this scope, observations were made in thermal hotels and semi-structured interviews were held with the senior managers of thermal hotels in Afyonkarahisar, Turkey. Thermal hotels were chosen as research areas because their potential guests are generally elderly and disabled tourists, and there may be more arrangements for disabled people in these hotels. As a powerful method of analyzing qualitative data, a thematic analysis was conducted on the data set. Results show no specific arrangement was made for the visually impaired guests, and participants think that physical regulations regarding accessibility may adversely affect the functionality of the service delivery process. In addition, arrangements for disabled people are focused on legal requirements.
Sustainable Tourism and an Analysis of Opportunities for and Challenges to Researchers and Professionals
Authors: Carvalho Fatima L. , Fernandes Silvia C.
Published: October 2022

This work analyzes academic work from 2004 to 2020 with an influence on the blueprint for sustainable tourism innovation strategies. Criteria used include verifying which are the main concerns, the contribution of sustainability indices, and implications to practitioners and high educational institutions in the area. This is increasingly important due to present and future challenges undermining the existence of a sustainable tourism industry. Accurate metrics can empower destinations, and higher education and its inner research must have a key role in the development of effective instruments. The challenge comprises selecting and monitoring them for sustainable tourism policy. Educational and research institutes with tourism studies should include in their syllabuses real cases and tools for developing key sustainability models and metrics to integrate and respond more promptly to critical challenges and trends.
Policies and Strategies for Institutional Participatory Governance
Authors: Vargas-Hernández José G.
Published: October 2022

This study aims to analyze the implications of policies and strategies for the institutional participatory governance framework. It begins by assuming the relevance of the policy analysis leading to the design and implementation of policies and strategies which have an effect on the institutional participatory governance. The method employed is the analytic-descriptive used to develop reflective thinking based on the theoretical, conceptual, and empirical literature. After a careful policy analysis, it is concluding that the design and implementation of policies and strategies are critical to develop and institutional participatory governance framework.
Deep Learning-Based Detection of Thyroid Nodules
Authors: K. V. H. Avani , Manjunath Deeksha , Gururaj C.
Published: October 2022

Thyroid nodule is a common disease on a global scale. It is characterized by an abnormal growth of the thyroid tissue. Thyroid nodules are divided into two types: benign and malignant. To ensure effective clinical care, an accurate identification of thyroid nodules is required. One of the most used imaging techniques for assessing and evaluating thyroid nodules is ultrasound. It performs well when it comes to distinguishing between benign and malignant thyroid nodules. But ultrasound diagnosis is not simple and is highly dependent on radiologist experience. Radiologists sometimes may not notice minor elements of an ultrasound image leading to an incorrect diagnosis. After performing a comparative study of several deep learning-based models implemented with different classification algorithms on an open-source data set, it has been found that ResNet101v2 gave the best accuracy (~96%), F1 score (0.957), sensitivity (0.917), etc. A simple and easy-to-use graphical user interface (GUI) has also been implemented.
Emotion-Based Human-Computer Interaction
Authors: K. Sujigarasharma , R. Rathi , P. Visvanathan , R. Kanchana
Published: October 2022

One of the important aspects of human-computer interaction is the detection of emotions using facial expressions. Emotion recognition has problems such as facial expressions, variations of posture, non-uniform illuminations, and so on. Deep learning techniques becomes important to solve these classification problems. In this chapter, VGG19, Inception V3, and Resnet50 pre-trained networks are used for the transfer learning approach to predict human emotions. Finally, the study achieved 98.32% of accuracy for emotion recognition and classification using the CK+ dataset.
Protein S on the surface of plasma lipoproteins: a potential mechanism for protein S delivery to the atherosclerotic plaques?
Authors: Baroni Marcello , Ferraresi Paolo , Ziliotto Nicole , Bortolotti Daria , Acciarri Pierfilippo , Martinelli Nicola , Marchetti Giovanna , Coen Matteo , Bernardi Francesco
Published: October 2022

The anticoagulant protein S (PS) binds phospholipids with very high affinity, but PS interaction with lipoproteins and lipidrich atherosclerotic plaques remains still poorly defined. We investigated PS in plasma lipoproteins and in atherosclerotic plaques from ten patients undergoing endarterectomy. PS was detected by Western blotting after exposure of the necrotic core to liposomes and was found to maintain its ability to bind phosphatidylserine micelles. The amounts of PS bound to low/very low-density lipoproteins in patient’ plasmas were higher and more variable than those detected in healthy subjects. A direct correlation between bound PS and low-density lipoproteins (LDL), plasma levels was found only in patients (r=0.921, p<0.001), thereby leading to hypothesize that the PS-phospholipids binding may increase by oxidative processes of LDL in atherosclerotic patients. The presence of the PS into the necrotic core of atherosclerotic plaques and on the surface of lipoproteins, particularly the atherogenic LDL, suggests a LDL-based delivery of PS to the atherosclerotic plaques and emphasizes the deep link between plasma lipids and coagulation in cardiovascular diseases.
Concussion Exposure and Suicidal Ideation, Planning, and Attempts Among US High School Students
Authors: Kay Jacob J. M. , Coffman Colt A. , Harrison Adam , Tavakoli Abbas S. , Torres-McGehee Toni M. , Broglio Steven P. , Moore Robert Davis
Published: October 2022

Context

Interest is growing in the association between repetitive concussions and mental health. However, studies on the relationship between concussion frequency and adverse mental health outcomes among female and male youth are lacking.

Objectives

To examine the association between self-reported concussion frequency and nonfatal suicidal behaviors among youth and to explore the possible interaction of biological sex.

Design

Retrospective cross-sectional survey.

Setting

National Youth Risk Behavior Surveillance System.

Patients or Other Participants

United States secondary school students (N = 28 442).

Main Outcome Measure(s)

Exposure variables were the frequency of self-reported sport- or recreation-related concussion in the previous 12 months (0, 1, ≥2). Outcome variables were feelings of self-reported sadness or hopelessness and suicidal ideation, planning, and attempts. Covariates were age, sex, race and ethnicity, bullying victimization, sexual orientation, and physical activity.

Results

Students who reported ≥2 concussions were at significantly greater odds of reporting suicidal attempts (adjusted odds ratio = 2.03; 95% CI = 1.43, 2.88) when compared with students reporting a single concussive event during the past 12 months. However, sex interactions revealed that this finding may have been driven by males; the strength of associations did not increase from single to multiple concussions among females.

Conclusions

Our findings suggest that adolescents who reported concussion were at increased odds of reporting poor mental health and suicidal behaviors. Moreover, an increased number of concussive events may be associated with significantly greater odds of reporting suicidal attempts, particularly among males. Irrespective of sex, health care professionals should closely monitor mental health behaviors in adolescents with repetitive concussions, especially those that occur in close temporal proximity.
Anatomical study of the adductor canal: three-dimensional micro-computed tomography, histological, and immunofluorescence findings relevant to neural blockade
Authors: Lee Shin Hyo , Kim Hee Jung , Kim Shin Hyung , Cho Tae-Hyeon , Kwon Hyun-Jin , O Jehoon , Hong Ju Eun , Nam Seung Hyun , Hwang Young-Il , Yang Hun-Mu
Published: October 2022

Background: A precise anatomical understanding of the adductor canal (AC) and its neural components is essential for discerning the action mechanism of the AC block. We therefore aimed to clarify the detailed anatomy of the AC using micro-computed tomography (micro-CT), histological evaluation, and immunofluorescence (IF) assays.Methods: Gross dissections of 39 thighs provided morphometric data relevant to injection landmarks. Serial sectional images of the AC were defined using micro-CT and ultrasonography. The fascial and neural structures of the AC proper were histologically evaluated using Masson’s trichrome and Verhoeff-Van Gieson staining, and double IF staining using choline acetyltransferase (ChAT) and neurofilament 200 antibodies.Results: The posteromedial branch insertion of the nerve to vastus medialis (NVM) into the lateral border of the AC proper was lower (14.5 ± 2.4 cm [mean ± SD] above the base of the patella) than the origin of the proximal AC. The AC consists of a thin subsartorial fascia in the proximal region and a thick aponeurosis-like vastoadductor membrane in the distal region. In the proximal AC, the posteromedial branch of the NVM (pmNVM) consistently contained both sensory and motor fibers, and more ChAT-positive fibers were observed than in the saphenous nerve (27.5 ± 11.2 / 104 vs. 4.2 ± 2.6 / 104 [counts/µm2], P < 0.001).Conclusions: Anatomical differences in fascial structures between the proximal and distal AC and a mixed neural component of the neighboring pmNVM have been visualized using micro-CT images, histological evaluation, and IF assays.
Surveying entry-level curriculum content in home modifications for occupational therapy programs
Authors: Meyer Margaret E , Priganc Victoria
Published: October 2022

Importance:

There is increased attention on the role the physical home environment plays in successful engagement in occupation.

Objective:

To examine how home modification content is integrated into the core curriculum in entry-level OT programs in the United States.

Design:

Web-based survey research.

Participants:

Program directors or their representatives.

Results:

All respondents include home modification instruction in their curriculum, however instructional time, where content lies in the curriculum, and resources vary widely. Sixty-eight percent do not utilize content experts and 34% do not offer hands-on learning experiences.

Conclusion and Relevance:

There is a risk for disparity in the scope and quality of home modification education provided to OT students that could negatively impact service delivery in this increasingly in-demand area of practice.
Procedural sedation in children for fractionated radiation treatment: Intranasal dexmedetomidine versus oral midazolam and ketamine
Authors: Das Rekha , Das Rajat , Jena Manoranjan , Janka Janaki , Mishra Sunita
Published: October 2022

Background and Aims:

Sedation in paediatric cancer for fractionated radiation treatment (RT) is unique as the child has to be still for accurate delivery of RT, monitoring of the child is from a remote location and sedation is repeated for multiple sessions of RT. The present study was undertaken to compare the efficacy of intranasal dexmedetomidine with oral midazolam and ketamine combination for repeated sedation during fractionated RT in paediatric oncology.

Methods:

Ninety children aged between 3-6 years, planned for 21 fractions of RT, were randomised to receive intranasal dexmedetomidine 2 mg/kg (group D) or oral midazolam 0.2 mg/kg and ketamine 5 mg/kg (group MK). The 21 sessions of fractionated radiotherapy were divided into three subgroups of seven consecutive exposures 1–7, 8–14 and 15–21 for comparison. The primary endpoint was to determine the incidence of successful sedation. The sedation score achieved, time to satisfactory sedation and discharge, rescue ketamine required, and side effects were secondary endpoints.

Results:

The incidence of successful sedation in the three successive RT subgroups; sessions: 1–7, 8–14 and 15–21, was 82%, 75.6% and 66.7% in group D, as compared to 40%, 24.4% and 13.3% in group MK, respectively. (P < 0.001). A decrease in successful sedation was noted in the successive subgroups. Time to successful sedation and discharge was earlier in group D in comparison to MK (P = 0.000). More patients in group MK required rescue ketamine (P = 000).

Conclusion:

Intranasal dexmedetomidine produces more satisfactory sedation as compared to oral ketamine with midazolam for fractionated RT.
Detection of paroxysmal nocturnal haemoglobinuria clones in cases of deep vein thrombosis in a tertiary care centre, western Rajasthan
Authors: Passey Siddhant , Purohit Abhishek
Published: October 2022

Background & objectives:

Paroxysmal nocturnal haemoglobinuria is a rare acquired disease characterized by bone marrow failure, intravascular haemolysis and thrombophilia. Thrombosis is the deadliest complication of paroxysmal nocturnal haemoglobinuria (PNH). The present study was conducted to study the prevalence of PNH in cases of deep vein thrombosis (DVT) which was previously undocumented from western Rajasthan.

Methods:

In the present cross-sectional study, 61 adult patients with DVT were tested using flow cytometry to detect PNH clones. Blood samples were processed using fluorescein-labelled proaerolysin, CD14, CD24, CD33 and CD45 panels for granulocytes and monocytes and CD59 and CD235a panel for red blood cells.

Results:

Three cases (4.92%) having large clones on monocytes as well as granulocytes, which fulfilled the diagnostic criteria of PNH were detected. Further, three cases (4.92%) showed small clones on both granulocytes and monocytes. Nine (15%) cases showed small clones only on granulocytes, and 11 (18%) cases showed small clones only on monocytes.

Interpretation & conclusions:

The results of the present study suggest that a higher proportion of patients had PNH in western Rajasthan compared to previously reported studies from elsewhere. It is suggested that PNH testing should be added to the procoagulant work-up panel in institutions of this region where it is not routinely done. This provides an otherwise missed opportunity to diagnose this disorder. Eculizumab may be employed, which is effective in reducing thrombophilic events in cases of PNH.
A Paraneoplastic Optic Neuropathy Revealing a Pulmonary Epidermal Carcinoma
Authors: Mouzari Yassine , Fiqhi Issam , Soukaina Belfaiza , Abdellaoui Taoufiq , Allaoui Mohammed , Reda Karim , Oubaaz Abdel Bar
Published: October 2022

Paraneoplastic optic neuropathy is a relatively rare ocular manifestation. We report the case of a patient with bilateral papilledema revealing a pulmonary squamous cell carcinoma. Paraneoplastic neuropathy is linked to an immune reaction by the presence of autoantibodies against collapsin responsive mediator protein 5 . Diagnosis is based on the determination of these autoantibodies and the search for occult cancer by PET scan. Treatment is often based on corticosteroid therapy and sometimes immunosuppressive treatment is necessary in the case of corticosteroid unresponsiveness.
The Internal Medicine Pharmacy Practice Workforce in Saudi Arabia
Authors: Korayem Ghazwa B. , AlDhahri Fahad , Alshaya Omar A. , AlSaleh Deemah , Al-Molaiki Maha A. , Alomar Mukhtar , Mubarki Sultan , Alsaqer Ahmed , Alturaiki Abdulrahman , Alharbi Alwaleed , Katz Michael D.
Published: October 2022

The need for healthcare reform in Saudi Arabia (SA) is mostly related to inadequate primary care services, the inconsistent quality of services, and the high demand for workforce capacity and capabilities. Therefore, the proposed healthcare transformation plan is part of the country’s overall transformation plan of Saudi Vision 2030, which aims to prevent morbidity and mortality associated with non-communicable diseases (NCD), communicable diseases, and avoidable injuries. Clinical pharmacists in internal medicine (IM) play an integral role in managing and preventing NCDs and communicable diseases. Most of the leading causes of mortality in SA can be prevented or managed with medications, and highly skilled pharmacist in medication therapy management. To improve the quality of health and well-being of the Saudi population, there is a need for a much larger number of well-trained IM clinical pharmacists in the public and private sectors. This opinion paper by the IM Pharmacy Specialty Network (PSN) of the Saudi Society of Clinical Pharmacy (SCCP) presents the current status of the IM pharmacy workforce in SA and provide initial phase recommendations to help develop the IM pharmacy workforce to serve the needs of the Saudi people. However, to meet the goals of Saudi Vision 2030, all healthcare systems need to work collaboratively with other stakeholders such as MOH, Ministry of Human Resources and Social Development, and SCFHS to prepare a highly skilled and effective Saudi healthcare workforce to meet the high demands of reforming the healthcare system.
Critical Care Pharmacy Program Accreditation Standards Framework and Core Competencies in Saudi Arabia
Authors: Alshaya Abdulrahman I. , Aljuhani Ohoud , Alghadeer Sultan Mohammed , Ismail Nadia , Alkhani Nada , Alharbi Shmeylan , Alenazi Ahmed O. , Almehizia Rayd , Alsulaiman Khalid , Aljabri Ahmed , Buksh Hussain , Alhammad Abdullah M.
Published: October 2022

Clinical pharmacy services in Saudi Arabia are expanding steadily, particularly with notable developments in critical care pharmacy services and training programs, including four critical care residency programs localized in Riyadh and one program in Jeddah. The Scientific Council of Pharmacy leads extensive efforts to advance clinical pharmacy practice and training under the Saudi Commission for Health Specialties (SCFHS), the accrediting body for critical care training programs and all other specialties. Despite launching critical care pharmacy programs in 2013, currently available accreditation standards and competency assessments for specialized residency programs in critical care were established in 2020. These accreditation standards and competency assessment modalities have been found to have significant areas of improvement based on the feedback of practicing critical care pharmacy residency program directors and trainees over the past few years. This is an opinion paper based on a consensus of critical care and emergency medicine pharmacy experts which recommends updating the current accreditation standards framework and competency assessment blueprint for specialized critical care pharmacy programs. Additionally, it highlights the need to modify the accreditation standards framework for critical care pharmacy programs. Further evaluation of these modalities can be revised as deemed reasonable by governmental authorities by recruiting practicing critical care clinical pharmacy experts.
Currents on cusped hyperbolic surfaces and denseness property
Authors: Sasaki Dounnu
Published: October 2022

The space

\operatorname{GC}(\Sigma)

of geodesic currents on a hyperbolic surface

\Sigma

can be considered as a completion of the set of weighted closed geodesics on

\Sigma

when

\Sigma

is compact, since the set of rational geodesic currents on

\Sigma

, which correspond to weighted closed geodesics, is a dense subset of

\operatorname{GC}(\Sigma)

. We prove that even when

\Sigma

is a cusped hyperbolic surface with finite area,

\operatorname{GC}(\Sigma)

has the denseness property of rational geodesic currents, which correspond not only to weighted closed geodesics on

\Sigma

but also to weighted geodesics connecting two cusps. In addition, we present an example in which a sequence of weighted closed geodesics converges to a geodesic connecting two cusps, which is an obstruction for the intersection number to extend continuously to

\operatorname{GC}(\Sigma)

. To construct the example, we use the notion of subset currents. Finally, we prove that the space of subset currents on a cusped hyperbolic surface has the denseness property of rational subset currents.
Assessing the Brighton Collaboration Case Definition of Sensorineural Hearing Loss in Ghana
Authors: Bukari Iddrisu , Huang Wan-Ting , Issahalq Duah Mohammed , Agyemang-Prempeh Akosua A. , Konney Anna , Yussif Hamidu , Yakubu Yakubu A. , Geisler Christopher Hammond , Chen Wei J.
Published: October 2022

The Brighton Collaboration has developed a case definition to assess sensorineural hearing loss (SNHL) as an adverse event of special interest for Lassa fever vaccines. We applied the level of diagnostic certainty (LOC) criteria to 300 SNHL patients aged 18 to 59 years at a tertiary hospital in Ghana from January 2017 through June 2020 and evaluated the applicability of this definition. Most SNHL cases were assessable (85.0%) and assigned level 1 LOC (84.3%); missing information on otoscopy (86.7%) was the main reason for being unable to classify cases. Consistency of LOC classification between assessors was 99.3%. Cases with electronic medical records (EMRs) were less assessable than those with paper records (30.9% versus 93.8%). These findings indicate that the SNHL definition would be applicable to retrospectively ascertain and classify cases in resource-limited settings. Developing an EMR template to document otoscopy results may improve the feasibility at this hospital to ascertain SNHL.
Antepfıstığı Psıllıdı Agonoscena Pıstacıae Burckhardt & Lauterer, 1989 (Hemıptera: Psyllıdae)’Ne Karşı Kullanılan Bazı İnsektisitlerin Uygulama Zamanının Araştırılması
Authors: USANMAZ Hakan , ASLAN Mahmut Murat , ÖZGEN İnanç
Published: October 2022

Bu çalışma, özelikle son yıllarda Güneydoğu Anadolu Bölgesinde ciddi verim kayıplarına neden olan Agonoscena pistaciae’nin mücadelesinde en fazla kullanılan 4 insektisitin farklı zamanlarda uygulanmasını karşılaştırmak amacıyla Gaziantep (Oğuzeli) ve Şanlıurfa (Birecik) illerinde 2016 yılında yürütülmüştür. Biyolojik etkinlik denemeleri şeklinde yürütülen bu çalışmada denemeler Gaziantep ilinde mayıs ayında kurulurken, Şanlıurfa ilinde ise ağustos ayında kurulmuştur. Denemelerde standart ilaç deneme metodu kullanılmıştır. Deneme 3 tekerrürlü olarak kurulmuş ve ilaçların ruhsat dozları ve kontrol denemenin karakterlerini oluşturmuştur. 3x3=9 ağaç bir parsel olarak alınmıştır. İlaçlamadan sonra sayımlar ortadaki ağaçlardan yapılmıştır ve ilaçlamadan önce, ilaçlamadan sonra ise 7, 14 ve 21. günlerde nimf sayımları yapılmıştır. Sayım sonuçları, yaprak örneklerinde her parselde sayılan canlı nimf sayımları üzerinden Henderson-Tilton formülüne göre değerlendirilmiştir. Aynı insektisitler mayıs ayında %90’ın üzerinde biyolojik etkinlik gösterirken; ağustos ayındaki uygulamada ise bu oran %90’ın altına düşmüştür. Bir insektisitin başarılı sayılabilmesi için en az %90‘lık bir etki göstermesi gerekmektedir. Bunun sebebinin ikinci uygulamada yapraklar üzerinde yoğun olarak bulunan fumajin tabakasının olduğu düşünülmektedir.
Dreaming, Temporality in Diasporic Space, and Religious Reflections among Kabyle Immigrant Converts in France
Authors: Rasmussen Susan
Published: October 2022

This article explores diasporic experiences and reflections on religious conversion through analyzing visitational, predictive/generative, and inspirational dreams recalled and related by Kabyle immigrant converts in France, which prompted their earlier conversion from Islam in their home region of Kabylie in Algeria, North Africa, prior to their migration to France. There is an approach to dreaming as both self-psychoanalysis and social practice in which visions in visitational dreams illuminate complex cultural identity and belonging in contexts of believed soul travel in dream time and transcultural migration over space. Useful in this analysis is Mikhail Bakhtin’s concept of the chronotope, referring to how configurations of time and space are represented in language—in the present case, dreams—analyzed here in terms of how converts’ dreaming, cultural theories of dreams, and dream-sharing construct ambiguous, changing, and ambivalent meanings of conversion in bringing together, but also highlighting contrasts between, cultural and religious distances over time and space. Pre- and post-conversion disruptions emerge in dreams that reveal both religious change and cultural continuity in ways these diasporic converts forge new meanings of identity and belonging as they cope with remembered political violence in Algeria and ongoing economic precarity, political discrimination, and social ambiguity in France. More broadly, an approach inspired by a Bakhtinian (1981) “chronotopic” metaphor hopefully opens up rich perspectives in the study of diasporic spaces and entangled religions in contexts of both conjunctions and disjunctions between dreaming and waking lifeworlds of contradictions and dilemmas over time.
İlkokul Ders Kitaplarında Rol Modellerin Cinsiyete ve Faaliyet Alanlarına Göre Dağılımı
Authors: EMRAL Tuğçe , ŞİMŞEK Ahmet , ÜTKÜR GÜLLÜHAN Nur
Published: October 2022

Öğrencilerin yaş itibari ile karakterlerinin henüz tam olarak oluşmadığı zamanlarda model alma önemli bir öğrenme şeklidir. Model almanın, öğrencinin rol model olarak seçtiği kişilerle özdeşim kurduğu düşünüldüğünde davranış gelişiminde önemli bir yer aldığı anlaşılmaktadır. Öğrencinin hayatı ile özdeşim kurabilme fırsatı bulunan derslerde ders kitaplarında yer alan rol modeller öğrencinin olumlu davranışları içselleştirmesine katkı sağlamaktadır. Bu araştırmanın amacı ilkokulda okutulan Türkçe, Hayat Bilgisi, Sosyal Bilgiler, Matematik ve Fen Bilimleri ders kitaplarındaki rol modellerin cinsiyet ve faaliyet alanlarına göre dağılımını tespit etmektir. Bu doğrultuda araştırmada Nitel Araştırma yöntemlerinden doküman incelemesi kullanılmıştır. İncelenen dokümanlar Türkçe 1. 2. 3. ve 4. sınıf ders kitapları Hayat Bilgisi 1. 2. ve 3. sınıf ders kitapları, Sosyal Bilgiler 4. sınıf ders kitapları, Matematik 1. 2. 3. ve 4. sınıf ders kitapları ile Fen Bilimleri 3. ve 4. sınıf ders kitaplarıdır. Ders kitapları incelendiğinde Matematik ders kitaplarında hiçbir rol modele rastlanmamıştır. 10 ders kitabında ise 110 farklı rol modele yer verildiği bu rol modellerin yalnızca 12’sinin kadın olduğu tespit edilmiştir. 4 kitapta rol modele rastlanmamıştır. Faaliyet alanı olarak tüm derslerde en sık “bilim” alanında rol modellere yer verildiği ve ardından “askeri” alanın geldiği tespit edilmiştir.
Risk and Return Analysis of Selected Flexi Cap Mutual Funds
Authors:   Associate Professor,Department of Commerce and Management,Mata Gujri Mahila Mahavidyalaya (Autonomous), Jabalpur, M.P., Punj Dr. Shruti
Published: October 2022

Mutual funds are considered by the investors as an ideal investment for people who are not having huge sum of money and wish to invest in a portfolio of stocks wherein the share price is quite high. The investors may or may not be aware about the ways investment could be done in stock market and there are different investment options which are available in the market based on a different risk and return. Flexi cap mutual funds offerfund managers a freedom for investing across themes/ sectors and market capitalizations. In Flexi Cap mutual funds, the fund managers could invest on the basis of outlook of market. These schemes generally recommended to the moderate investors for creating wealth over long time period. This study is based on the evaluation of risk and return of different flexi cap mutual funds and compares the performance of these funds so as to find the best flexi cap fund based on different measures of return and risk. Based on the average of the monthly returns, though it is negative, the lowest average negative return is of Aditya Birla and Parag Parikh Flexi Cap mutual funds. The maximum times the highest return has been of Parag Parikh Flexi Cap mutual fund during different quarters. Based on the average Annual return, highest return is of Parag Parikh Flexi Cap mutual fund, followed by UTI Flexi Cap fund, SBI Flexi Cap fund, PGIM Flexi Cap fund and Aditya Birla Flexi Cap mutual fund.
Thoracic Spine Deformity Post Tetanus: A Case Report of Tetanus Post Circumcision
Authors:   Department of surgery, School of medicine and Pharmacy, University of Rwanda, SHINGIRO Eric
Published: October 2022

Tetanus is caused by clostridium tetani bacteria through skin breach. The tetanus is characterized by tonic contraction and muscle spasm which can cause vertebral fracture in some patients. we are reporting a young male patient who after ring circumcision technique had tetanus complicated into thoracic vertebral fracture with severe kyphotic deformity and lower limb functional impairment. The surgical management was performed in two stages: First stage consisted of Shwab 2 osteotomy, pedicle screws and rod fixation with good result for deformity correction. The second stage of surgery involved left transpedicular T6 and T5 corpectomies (Shwab 3 osteotomy) plus interbody titanium cage fixation which provided good spinal cord decompression. Tetanus is still a major complication of circumcision, tetanus complication may be devastating Early surgical deformity correction and spinal cord decompression provide favorable neurological and functional outcome for patients with spine deformity post tetanus. The Patient was able to walk with crutches 3 months post-surgery.
On the Phonetic Similarity of the Word ‘Tooth’ in Various World Languages: Linguistic Notes of a Dentist
Authors:   Department of Health & Biomedical Sciences, Marseille University, Mahmood Mohammed Khalid
Published: October 2022

Some languages come from historical common ancestors and they share similarity on the basis phonology, morphology, syntax, semantics and pragmatics. Some words resemble each other between remote and even unrelated languages. Apart from historical borrowing, this is mainly due to common ancestor language. Degree of lexical similarity is one of the methods to measure word and cognate resemblance between languages. For this purpose, some lists have been proposed by professionals that contain words with the slightest possibility of borrowing from another language and the highest durability throughout time. The word for ‘tooth’ is present in all these lists. This shows the stability of this word and accounts for its similitude among world languages.