bluuebunny/crossref_metadata_2025 huggingface dataset:
Дискурсивный разлом социального поля: Уроки Евромайдана
Authors: Байша Ольга
Published: June 2021

Опираясь на теорию дискурса Эрнесто Лаклау и Шанталь Муфф, дальнейшее ее развитие в трудах этих ученых и в разработках Нико Карпентье по социальным антагонизмам, автор рассматривает украинский Евромайдан как дискурсивную формацию, определяющую социальные смыслы. Приведенный в книге дискурсивный анализ показывает, насколько важно признать и осмыслить антагонизм прогрессивного социального воображения, сформулированный в рамках манихейского дуализма: «прогрессивные мы» и «отсталые они». Представляя сложные социальные проблемы как простые дихотомии, «прогрессивные» дискурсы Евромайдана и других общественных движений за демократию и социальную справедливость на самом деле разрушают демократию, уничтожая необходимое для коммуникации общее символическое пространство. Создаются условия, при которых вместо одного общества появляются два, причем конфронтация между ними становится ожесточенной, а установленная граница — непреодолимой. И это противостояние может привести не только к символическому, но и к физическому уничтожению друг друга — таковы уроки украинского кризиса. Книга адресована политикам и общественным деятелям, политологам и социологам, а также широкому кругу читателей. Книга предназначена для политологов, философов, социологов, историков и всех интересующихся социальной философией и полити­ческой теорией.
Determination of ochratoxin a in coffee by ELISA method and its relationship with the physical, physicochemical and microbiological properties
Authors: Monsalve-Atencio Robinson , Sanchez Karolay , Camaño Jairo , Lopera-Cardona Seneida , Ortiz-Reyes Blanca
Published: June 2021

BACKGROUND: Coffee is one of the most consumed beverages in the world; however, it may contain toxic compounds such as ochratoxin A (OTA). OBJECTIVES: Determine the OTA’s presence in different types of coffee, intended for beverage preparation and marketed in Colombia through the application of the enzyme-linked immunosorbent assay (ELISA) and analyze its relationship with the physical, physicochemical and microbiological properties. METHODS: 8 samples of coffee commercialized in the Colombian market were selected, in which the OTA content was determined by applying the ELISA method. Likewise, a microbiological analysis was performed, and physicochemical properties were determined, such as moisture content, aw, percentage total dissolved solids (%TDS), and extraction yield (%EY). Physical properties such as free-flow densities, compacted bulk densities (CBD), porosity, average particle size (ASP), and color. The data were treated with multivariate analysis using Principal Component Analysis (PCA) and Cluster Analysis (CA) to quantitatively investigate the relationships between the coffee samples concerning their physical, physicochemical properties, and OTA content. LSD test was applied with a significance level of 95 % and Pearson correlation test. RESULTS: All the samples had OTA content, but only 2 exceeded the limits allowed by the regulations, with a maximum value of 15.449 µg/Kg, which represents 31.449 % of the tolerable daily intake according to the parameters defined by Joint FAO/WHO Expert Committee on Food Additives (JECFA). According to the PCA and CA, the samples were grouped harmonically according to the type of coffee associated with its commercial presentation and industrial process, OTA content, and ASP. OTA content was significantly and positively correlated (p < 0.05) with %EY, %TDS, ASP, porosity, CBD, and moisture. CONCLUSIONS: The coffees marketed in Colombia showed a variable range of OTA, where soluble coffees had higher OTA contents than roasted coffees, and 25 % of the coffees analyzed do not meet the levels defined by Colombian regulations. The OTA content in coffee is related to properties that define the ability to extract solutes from coffee.
Diseño universal para el aprendizaje, una práctica para la educación inclusiva. Un estudio de caso
Authors: Delgado Valdivieso Karina
Published: June 2021

En la actualidad los docentes demandan de metodologías para ser aplicadas según la diversidad de estudiantes. El diseño universal para el aprendizaje(DUA) es un enfoque didáctico, permite conocer las metodologías y estrategias que utiliza cada docente dentro de las instituciones educativas,marcando el camino hacia una inclusión efectiva, desde una visión humanista, en la que todos los estudiantes deben ser atendidos considerando sus diferentes condiciones, pasando a una atención ante la heterogeneidad de los estudiantes, es por ello que siempre será necesario realizaradaptaciones curriculares para mejorar el aprendizaje de todos los estudiantes, amparadas en los principios de la representación, ejecución yexpresión e implicación. Este artículo detalla las experiencias y aportes de los estudiantes de la Universidad Tecnológica Indoamérica de la Maestría en Educación mención Pedagogía MEDU 2- 4, como experiencia para realizar una planificación con el DUA, aplicadas al octavo año de Educación General Básica en el área de Estudios Sociales. La planificación será desarrollada para todos los estudiantes, así como las precisiones en caso de unacondición de una discapacidad auditiva y un autismo, así como una necesidad educativa especial no asociada a una discapacidad por una dislexia.
Hozzájárul-e a helyi élelmiszer vásárlás a helyi gazdaság fejlődéséhez? Egy szisztematikus irodalmi áttekintés
Authors: Szente Viktória , Fertő Imre , Benedek Zsófia
Published: June 2021

Általános feltevés, hogy a helyi élelmiszerek értékesítése pozitív hatással van a helyi gazdaság teljesítményére. Cikkünkben megvizsgáljuk, hogy az eddigi kutatások mennyiben támasztják alá ezt a vélekedést. A ScienceDirect, Wiley Online Library, Taylor and Francis Online, SpringerLink, AgECON, Emerald és Sage adatbázisban fellelhető, 2000 és 2019 között publikált, angol nyelvű folyóiratcikkek kerültek szisztematikus áttekintésre. Emellett kiegészítő keresést végeztünk a Google Tudós keresőmotor felhasználásával. A téma jellegénél fogva több szinonima figyelembe vételével végeztük az adatgyűjtést, ami adatbázisonként 42-féle kulcsszavas keresést eredményezett. A multiplikátor hatás négyféle tényezőjére: a kibocsátási, a hozzáadott érték, a jövedelmi, valamint a foglalkoztatási multiplikátorra vonatkozóan kerestünk információkat.

Az első körben beválogatott 14 819 cikk közül mindössze 25 felelt meg a kutatási kritériumoknak. 24 közlemény szerint a helyi élelmiszerek iránti kereslet növekedése pozitív hatást gyakorolt a multiplikátor hatás valamely mutatójára, de 6 esetben más mutató esetében már nem tudtak ilyen kedvező hatást kimutatni. Egy tanulmány pedig egyik tényező esetében sem talált összefüggést. Eredményeink szerint a helyi élelmiszerek pozitív hatása leginkább a foglalkoztatásban és a jövedelmek növekedésében megfigyelhető, míg a kibocsátási és a hozzáadott érték multiplikátorok megjelenése sokkal inkább helyzetfüggő, nehezen vagy nem kimutatható. A jelenleg használt módszerek legtöbbjénél továbbá kisebb-nagyobb felülbecslés is feltételezhető. A helyi élelmiszerek helyi gazdaságra gyakorolt valós hatásának méréséhez további kutatásokra van szükség.
Who gains from economic freedom? A panel analysis on decile income levels
Authors: Lawson Robert , Dean James
Published: June 2021

This paper revisits Saccone’s (2020) analysis of the impact of economic freedom on decile income shares for a panel of developed and developing nations during 1980-2014. Saccone found that higher levels of economic freedom corresponded with lower income shares for the bottom 8 deciles and higher shares only for the top 2 deciles. Instead of decile income shares, this paper focuses on the impact of economic freedom on decile income levels. We find that the income per capita for all 10 deciles increases as economic freedom increases.
Growth and ideas in a perfectly competitive world: A complement
Authors: Boitier Vincent
Published: June 2021

In this short article, I build an idea-based growth model with perfect competition in a representative household economy. I obtain significant findings that confirm Boitier (2019). First, a competitive equilibrium, increasing returns to scale, and innovations can be tenable. For that, firms must raise capital from shareholders, and the production function must show decreasing returns to scale in the stock of ideas and in labor. Second, the developed idea-based growth model admits a balanced growth path similar to the one provided in an idea-based growth model with monopolistic competition. Whether innovations are competitive or thrive under monopolistic competition does not constitute an engine-driving long-run growth. Importantly, this reconciles Romer (1990, 2015) with Boldrin and Levine (2008).
América Latina en movimiento: Competencias y habilidades para la Cuarta Revolución Industrial en el contexto de pandemia: Resumen ejecutivo
Authors: Basco Ana Inés , Lavena Cecilia
Published: June 2021

Los acelerados procesos de cambio tecnológico y productivo, evidente en el desarrollo de economías cada vez más basadas en servicios y en la expansión de las plataformas digitales como espacios de interacción, se vio atravesado por la pandemia global por COVID-19. En este marco, los países latinoamericanos enfrentan el desafío de acceder a nuevos mercados e incrementar el comercio, la productividad laboral y el valor agregado de las exportaciones, tanto dentro de la propia región como con el resto del mundo. Este documento busca entender en este contexto los cambios en materia de adopción tecnológica, modalidades de trabajo y demanda de habilidades laborales en Argentina, Brasil, Chile, Colombia y México y analizar sus diferencias con la etapa pre-pandemia.
Przebaczenie sobie jako cel wychowania
Authors: Horowski Jarosław
Published: June 2021

Przebaczenie sobie stanowi jedną z najbardziej kontrowersyjnych decyzji, nie tylko ze względu na fakt samodzielnego uwalniania się od konsekwencji moralnie złych wyborów dokonywanych przez jednostkę, ale także z uwagi na łączenie go z ukrytym, udzielanym sobie, przyzwoleniem na wykonywanie podobnych aktów w przyszłości. Równocześnie w literaturze psychologicznej ukazywane są pozytywne aspekty przebaczenia sobie. Niniejsze analizy poświęcone są moralnej wartości przebaczenia sobie i w konsekwencji prawomocności włączania go jako celu w proces wychowania. W kolejnych punktach najpierw decyzja o przebaczeniu sobie porównywana jest do aktów samouniewinnienia, samousprawiedliwienia i samoułaskawienia, następnie analizowany jest czyn, w odniesieniu do którego jednostka ma prawo podjąć decyzję o przebaczeniu sobie, wreszcie podejmowana jest refleksja nad procesem przebaczenia sobie oraz jego warunkami.
Nauczanie etyki z perspektywy kształcenia ogólnego
Authors: Stępkowski Dariusz , Pękala Joanna Ludwika
Published: June 2021

Lekcje etyki funkcjonują w polskim systemie oświatowym od blisko trzech dekad. Autorzy przeprowadzają ich analizę ze względu na trzy sensy kategorii kształcenia ogólnego: jako idei edukacji ogólnodostępnej, jako kryterium doboru treści nauczania i jako zasady integrowania działania edukacyjnego i nieedukacyjnego – (samo)kształceniowego. Na tej podstawie wysuwają postulat refleksji nad edukacją moralno-etyczną w szkole, której tylko jedną z części są/mogą być lekcje etyki.
Socratic as Mathematics Learning Application for Differential Equations Concept
Authors: Yanuarto Wanda Nugroho , Jaelani Anton , Purwanto Joko , Zakaria Mohamad Ikram
Published: June 2021

Technological improvements in the era of the Industrial Revolution 4.0 can be applied to learning mathematics as a medium of improving teacher performance. In addition, a pandemic situation forces teachers and students to implement online learning. One of the learning media that can help teachers in learning mathematics online is Socratic. The Socratic system generally consists of four basic components: acting humanely, thinking humanely, thinking rationally and acting rationally. For example, the Socratic can provide alternative solutions to the differential equations problems. Mathematics problems can be recorded by the Socratic through three main features:1) home screen, which is used to take pictures of solving the problem needed; 2) search results, the image that has been recorded will be searched for a solution through Socratic's artificial intelligence in internet database, and 3) an explanation, the search results that have been obtained, have their own explanation. Teachers and students as users may find the best solution for each explanation by the Socratic. Meanwhile, this study uses four stages of the literature review process:1) search for relevant literature, 2) evaluation and source selection, 3) identification of themes, and 4) outline of the structure of the writing. This paper systematically investigates the use of the Socratic as a technology application that can assist mathematical problems.
Effectiveness of Human Detection from Aerial Images Taken from Different Heights
Authors: Hakimy Salem Muhammad Shahir , Kamaru Zaman Fadhlan Hafizhelmi
Published: June 2021

Recently, drones have been regularly used to aid in search and rescue in places where it is normally to carry out some of the early forensic victim localization. There are many suitable human detectors for drone use, such as Histogram Oriented Gradient (HOG), You Only Looks Once (YOLO), and Aggregate Channel Features (ACF). In this paper, the height of the aerial images is analyzed for its effect on the accuracy of the detection. This works compares ACF, YOLO MobileNet, and YOLO ResNet50 using a different set of aerial images varying at 10m, 20m, and 30m heights. The results show that in a single-model test, with our proposed bounding-box standardization, YOLO MobileNet achieves significant increase in test precision (AP), with 0.7 AP recorded. For single-model test, YOLO MobileNet yield best AP using 20m training data where it obtained AP of 0.88 (10m test height), 0.82 (20m test height), and 0.91 (30m test height).
Web-based Information Management Systems Feature Usage Case Study on European Telecom Sector
Authors: Șandor Andrei
Published: June 2021

Modern service providers use web-based information management systems (IMS’s) to enhance their relationship with customers. This helps them better manage customer-related data and information. Also, the use of search engines, user management features, chat-bots or forums can help customers manage their own data, like consumption or invoices. So, the use of web-based information management systems may be the ideal solution for a win-win relationship between a service provider and a customer. The study of the features embedded in websites may reveal some insights regarding the way they are used and how they will look like in the future.
Adaptación del Cuestionario de Regulación Emocional (ERQ) en población adulta de la Ciudad Autónoma de Buenos Aires y el Conurbano Bonaerense
Authors: Pagano Alejandro Emilio , Vizioli Nicolás Alejandro
Published: June 2021

El presente estudio consistió en la adaptación lingüística, conceptual y métrica del Cuestionario de Regulación Emocional (ERQ; Gross & John, 2003). El mismo es una medida de autoinforme conformada por 10 reactivos que permiten la evaluación de dos estrategias de Regulación Emocional: la reevaluación cognitiva (6 ítems) y la supresión expresiva (4 reactivos). Para llevar adelante la adaptación se realizó una traducción directa del cuestionario del inglés al español seguido por procedimiento de juicio de expertos y un análisis de discriminación de reactivos. Luego de esto se indagó la estructura factorial de la versión a partir de análisis factoriales confirmatorios en una muestra compuesta por 250 adultos entre 18 y 63 años (M = 32.28, DE = 11.74), residentes en la Ciudad Autónoma de Buenos Aires y en el Conurbano Bonaerense. Por último, se buscó evidencia de la confiabilidad del instrumento y se establecieron valores normativos. Los resultados indican que la versión adaptada del ERQ presenta adecuada validez de contenido (porcentajes de acuerdo entre .80 y 1), adecuada validez factorial para el modelo de dos factores independientes, S-Bc2(27) = 61.98, NNFI = .91, CFI = .93, RMSEA (.05 - .10) = .07, AIC = 7.98, evidenciando índices de consistencia interna aceptables (α ordinal = .81 y ω ordinal = .87 para el factor reevaluación cognitiva; y α ordinal = .71 y ω ordinal = .79 para el factor de supresión expresiva).
Opcije, terminske pogodbe in model binomskega drevesa: Skripta pri predmetu Temelji finančnega inženiringa
Authors: Marovt Janko
Published: June 2021

Skripta »Opcije, terminske pogodbe in model binomskega drevesa« je namenjena slušateljem predmeta Temelji finančnega inženiringa, ki se izvaja na Faklteti za naravoslovje in matematiko. V njej so predstavljeni temeljni pojmi finančnega inženiringa. Najprej so podane predpostavke, na katerih temelji večina matematičnih modelov, ki simulirajo dogajanja na finančnih trgih. Dokazi trditev in izrekov so utemeljeni na načelu nearbitražnosti. Predstavljeni so nekateri izvedeni finančni instrumenti. Tako so v osrednjem delu skripte najprej analizirane standandizirane in nestandardizirane terminske pogodbe. Sledi predstavitev modela binomskega drevesa in njegova uporaba pri vrednotenju evropskih in ameriških nakupnih ter prodajnih opcij. Skripta je opremljena s številnimi rešenimi zgledi in primeri.
For the Benefit of All: Faculty-Led Undergraduate Research in the Humanities at LaGuardia Community College, CUNY
Authors:   LaGuardia Community College-CUNY, Stubbs Naomi J.
Published: June 2021

This case study highlights the benefits of one example of humanities student-faculty collaboration at LaGuardia Community College, CUNY, in which a critical editing project was enhanced by student contributions, while the students gained skills that encouraged retention and nurtured future success.
Fear of Childbirth and Associated Factors Among Pregnant Mothers Who Attend Antenatal Care Service at Jinka Public Health Facilities, Jinka Town, Southern Ethiopia
Authors: Yetwale Aynalem , Melkamu Eneyew
Published: June 2021

BACKGROUND

Women face many challenges from conception to postpartum, and fear of childbirth is one of the challenges the women encounter during pregnancy. This could have resulted from different perspectives and it could in turn lead to various pregnancy and childbirth problems. Thus, understanding childbirth fear and factors associated with this is of paramount importance and this study was aimed at addressing this issue.

METHODOLOGY

A facility-based cross-sectional study was done on 423 pregnant mothers who came for antenatal care services at Jinka hospital and Jinka health center. The study was conducted from June 1to 30, 2018. The sample size was calculated using the single population proportion formula and samples were taken after proportional allocation was done for the hospital and health center using the proportion allocation formula. Individual participants were selected with a systematic sampling technique using k-value of 2 for both the hospital and health center and the first participant was selected by the lottery method from the first two samples. Data were entered into epi-data version 3.1.1. and exported into statistical packages for social sciences version 21.0 for cleaning and further analysis. The level of significance was declared at a p value of less than 0.05 in multivariable logistic regression model. Narratives, figures, and tables were used to put the result.

RESULT

From 423 samples, two of the questionnaires were incomplete and thus 421 were used for analysis giving a response rate of 99.5%. Around a quarter of 102 (24.2%) mothers had fear of childbirth and the remaining 319 (75.8%) had no fear of childbirth. From the factors under consideration, history of previous pregnancy complications, previous history of labor and delivery complications, educational status, and depression status were significantly associated with a mother's fear of childbirth.

CONCLUSION

Even though it is physiological to have some fear of childbirth, the figure obtained is relatively higher. Factors found to have a significant effect on childbirth fear are those which could be tackled through improved health literacy and integrated maternal health services.
As concepções de criatividade na Base Nacional Comum Curricular de Língua Portuguesa
Authors: Paes Washington Elias , Silva Carlos Mágno Domás da
Published: June 2021

The objective of this paper is to analyze the concepts of creativity that underlie the propositions given by the National Common Curricular Base (BNCC) for the Portuguese Language curricular component. This study is justified by the growing social relevance attributed to creativity and its expression. It begins with the analysis of some concepts and perspectives on the phenomenon of creativity. Following, the occurrences of the term “creativity” and cognates in the BNCC are analyzed, relating its manifestations to the theoretical concepts discussed in the study. Finally, we emphasize that, despite the frequent use of terms such as “creative”, in the Portuguese Language sections of the BNCC, we do not find a systematic and critical approach to the theme, to the encouragement and development of creativity and creative expression. Creativity is linked, above all, to textual production, especially the construction of fictional narratives. In a socio-historical sense, it is treated in a pragmatic and immediate manner, being present only when demonstrated by results, that is, in the creation of processes and products that meet the demands. The research methodology is based on literature review.
Efeitos adversos da maquiagem para a área dos olhos e notificação no NOTIVISA
Authors: Sousa Maria de Fátima Vieira de , Ferreira Jaise Silva
Published: June 2021

Makeup for the eye area is used by many women around the world. Mascara, eyeliner, eyeliner and eye shadow are some of the cosmetics used. The objective of this study was to evaluate the knowledge of women in Campos dos Goytacazes (Brazil) about possible adverse effects of eye makeup, and whether they know and / or have already reported to the Health Surveillance Notification System (NOTIVISA) in case of such effects. An online form was sent via social media such as Facebook, Instagram and WhatsApp. A group of 196 women were interviewed, among them 159 residing in the city of Campos dos Goytacazes (Brazil). The survey revealed that 66.7% of the women interviewed are unaware of the adverse effects that can be caused by eye makeup, 79.9% do not know the NOTIVISA system, and 95.0% have never used it. The study suggests the development of ways of disseminating the NOTIVISA system, as well as awareness campaigns on the use of these cosmetic products, mainly because they are considered harmless to health.
Patologia Vestibular em Idade Pediátrica: Análise Retrospetiva e Revisão da Literatura
Authors: Lima António Fontes , Moreira Filipa Carvalho , Menezes Ana Sousa , Costa Isabel Esteves , Azevedo Cátia , Vilarinho Sergio , Dias Luis
Published: June 2021

Introdução: A patologia vestibular na população pediátrica é um tema bastante controverso, mas que tem ganho cada vez mais destaque. A prevalência reportada nesta população varia entre 0,7% e 15%. No entanto, este valor pode estar subestimado, uma vez que a sua forma de expressão na população pediátrica é muito diferente da dos adultos, podendo ir desde a vertigem rotatória até queixas de alterações da visão, cefaleias, atraso motor ou dificuldades na aprendizagem. Embora na literatura a otite média com efusão seja considerada a principal causa de disfunção vestibular nesta faixa etária, existem outras que devem ser consideradas. O objetivo deste estudo foi descrever as características clínicas da população pediátrica encaminhada para avaliação em consulta de Otorrinolaringologia num hospital terciário, por suspeita de disfunção vestibular, desde o ano de 2013 até 2017; Também se pretendeu comparar os resultados e realizar uma revisão da literatura acerca das etiologias mais frequentes, características diagnósticas e abordagem terapêutica.Material e Métodos: Foram analisados de forma retrospetiva os processos clínicos dos doentes observados na consulta de subespecialidade de Vertigem de Otorrinolaringologia com idades entre 0 e 18 anos. Foram excluídos os doentes com diagnóstico de otite média com efusão.Resultados: Cumpriam os critérios de inclusão 37 doentes, dos quais 59% eram do sexo feminino, sendo a idade média da primeira consulta de 10,9 anos. O motivo mais frequente de referenciação foi a vertigem rotatória. As náuseas e cefaleias foram também sintomas frequentemente descritos. Todos os doentes foram submetidos a audiometria tonal; a videonistagmografia foi realizada em 41% dos casos; exames de imagem foram realizados em 59% dos doentes. No que respeita às etiologias do quadro, as mais frequentes foram a enxaqueca vestibular e a vertigem paroxística benigna da infância (ambas em 27% dos casos), seguida da neuronite vestibular (em 22% dos casos).Discussão: Embora os resultados sejam, em parte, sobreponíveis à literatura, comparativamente a outros centros de referência a diversidade de motivos de referenciação e de patologias é menor, o que pode apontar para o subdiagnóstico da disfunção vestibular nesta faixa etária.Conclusão: A disfunção vestibular em idade pediátrica pode ter uma multiplicidade de etiologias, pelo que pediatras, neurologistas, fisiatras, médicos de família e otorrinolaringologistas devem estar alerta para as diversas formas de apresentação desta entidade. Deverão ser criados protocolos de referenciação e avaliação adequados para esta população.
Seroprevalence of Anti-SARS-CoV-2 Antibodies Three Months Post Infection in Healthcare Professionals at an Oncology Hospital in Northern Portugal
Authors: E Silva Daniela Fonseca , Silva Paulo Dias , Torgal Ana , Braga Sara , Rocha Diana , Ochoa Carlos , Oliveira Álvaro , Rocha Luís , Dias Joana Marinho , Baldaque Inês
Published: June 2021

N/a.
EFFECTIVE THERMOPHYSICAL PROPERTIES OF POWDER MATERIALS DURING SINTERING UNDER ELECTRONBEAM HEATING
Authors: Romanenko Yurij M. , Stepanov Oleg V. , Loboda Petro I. , Bogomol Iurii I.
Published: June 2021

Background. Development of the consolidation processes of powder products using highly concentrated energy sources is impossible without a detailed analysis of the processes of thermal conditions arising in these products.
Objective. The aim of the study is to select a method for calculating the thermal conductivity of a porous body, which will be established under various conditions of electron-beam sintering of molybdenum compacts, and to study the effect of the parameters of the porous structure on the thermal conductivity.
Methods. An analysis of the sintering process in finite element calculations, in problems of thermal conductivity for two-dimensional and three-dimensional domains, simulating the real porous structure of molybdenum compaction and a regular porous structure with dense packing of spheres is proposed.
Results. Mathematical analysis of the contribution of re-radiation to the total thermal conductivity of the porous material is performed. The obtained dependences of the relative thermal conductivity on the porosity of the material and the relative radius of contacts between its particles are presented.
Conclusions. According to the results of the mathematical analysis of the conditions of heat transfer in a porous compact of molybdenum for the case of electron-beam heating, it was found that the radiant component of the thermal conductivity of a porous body with pores of the order of 2.5 μm is four orders of magnitude less than the conductive component of its thermal conductivity. Based on the results of finite element modeling of two-dimensional and three-dimensional porous objects, a significant effect of the contact area between particles on their integral thermal conductivity has been established, especially at small sizes of these contacts. At the same time, almost linear effect of porosity on thermal conductivity was established at contact radii between particles > 0.1 Rparticles. A significant influence of the uniformity of the distribution of contacts in aporous material on the uniformity of the temperature field in it is shown.
SIMULATION OF COMPACT POLARIZERS FOR SATELLITE TELECOMMUNICATION SYSTEMS WITH THE ACCOUNT OF THICKNESS OF IRISES
Authors: Bulashenko Andrew V. , Piltyay Stepan I. , Demchenko Ivan V.
Published: June 2021

Background. One of the main problems in modern satellite telecommunication systems is to increase the volume of information transmission with simultaneous preservation of its quality. Key element of such systems is antenna systems with polarization processing, which is carried out using polarizers. Therefore, development of new polarizers and simple techniques for their analysis and optimization are important problems. The most simple, effective, technological and actual for analysis are polarizers based on waveguides with irises.
Objective. The purpose of the paper is to create a mathematical model of the polarizer based on a square waveguide with irises, which allows analyzing the influence of polarizer’s design parameters on its electromagnetic characteristics.
Methods. A mathematical model of the waveguide polarizer with irises is created by decomposition technique using transfer and scattering wave matrices. To take into account the irises’ thickness their equivalent T- and Π-shaped circuits were used.
Results. We have developed mathematical model of the waveguide polarizer with irises, which takes into account their thickness and is based on the complete scattering wave matrix of the waveguide polarizer. The matrix has been obtained using the microwave circuit theory. The main characteristics of the waveguide polarizer were defined using matrix elements. The optimization of characteristics of a polarizer was carried out in the operating Ku-band 10.7–12.8 GHz.
Conclusions. Suggested mathematical model of a waveguide polarizer with irises provides the account of heights of irises, distances between them and their thickness. The results obtained show that this model is simpler and faster for the calculation of electromagnetic characteristics compared to finite elements method, which is often used for analysis of microwave devices for various applications.
EVALUASI KONDISI LINGKUNGAN DAN SARANA PENYELAMATAN PADA GEDUNG PERKULIAHAN TERHADAP BAHAYA KEBAKARAN
Authors:   Universitas Muhammadiyah Yogyakarta, Saleh Fadillawaty , Amalia Sinta ,   Universitas Muhammadiyah Yogyakarta, Prayuda Hakas , Tiyani Lilis ,   Politeknik Negeri Jakarta, Al Zakina Bella ,   Universitas Bojonegoro
Published: June 2021

Many aspects must be considered in the building's design so that the construction is sturdy and can be used according to its function. An important aspect that is often overlooked is the aspect of fire safety. This study aims to evaluate environmental conditions and safety facilities in buildings against fire hazards. The buildings reviewed are the Postgraduate Building, E6, E7, and F3 Building of the Muhammadiyah University of Yogyakarta. The research method used in this research is a qualitative approach, and the primary data is obtained by direct observation in the field and interviews with the person in charge of the building. This study indicates that the Postgraduate Building, E6, E7, and F3 Building's environmental conditions are not in good condition because each building gets a condition value of 51.67%; 50.56%; 52.22%; and 50%. The rescue facilities in the Postgraduate Building, E6, and E7 Building are good; although there are some shortcomings, the value of the condition of each building is 85.98%, 87.41%, and 87.41%. The rescue facility in the F3 Building is quite good, with a condition value of 65.81%.
Strengthen the Impact of CSR Information and Audit Quality on Investment Decisions: The Role of Good Corporate Governance in ASEAN Countries
Authors: Istianingsih Istianingsih , Rizal Putri Vidiyanna , Grace Haque Marissa
Published: June 2021

This research contributes to the development of theories regarding the relationship between Corporate Social Responsibility (CSR) and investment decisions. Acquisition of stock returns that exceed normal predictions depends on the successful implementation of Good Corporate Governance (GCG). This study aims to examine investors' reactions to information on CSR disclosure in several countries that are members of the Association of Southeast Asian Nations (ASEAN). Furthermore, this study also examines the role of implementing GCG in strengthening the impact of CSR disclosure on investor relations as measured by abnormal stock returns. The sampling technique used was purposive Sampling. The research was conducted on Manufacturing Companies in countries that are members of ASEAN during 2017-2019. The estimation model used to analyze data is a multiple regression model. The results showed that CSR information was able to increase investors' positive reactions. Meanwhile, GCG practice is proven to strengthen the impact of CSR information on investment decisions. Other variables involved in this study, namely audit quality, company size, debt level, and sales growth, are not proven to influence abnormal stock returns.
Clinical Advantage of Attaining Index-Based Remission Criteria prior to Composite Remission in Treating Rheumatoid Arthritis
Authors: Yoshii Ichiro , Chijiwa Tatsumi , Sawada Naoya
Published: June 2021

Background and objectives: The clinical advantage of targeting index-based remission criteria (IR) prior to Boolean remission (BR) was evaluated retrospectively. Materials and Methods: A total of 578 patients with rheumatoid arthritis (RA), who were treated for more than three years, were recruited. Patients who were treated to targeted IR and composite measure remission criteria such as BR from the first consultation were divided according to the turn of attaining BR and IR: IB-R, a group that matched IR at the same time BR is attained or earlier; BI-F, a group that attained BR followed by IR or failed; IR-BF, a group that could not attain BR despite attaining IR; Both-F, a group that failed to attain either BR or IR. Background factors were statistically compared among groups. The BR rate in patients who attained IR (BRR) and the rate of failure to attain IR in patients who failed to attain BR (BFR) were statistically evaluated. Results: Groups made of 225, 231, and 482 in IB-R; 160, 154, and 8 in BI-F; 18, 18, and 75 in IR-BF; and 175, 175, and 13 in Both-F when indexing the clinical disease activity index (CDAI), simplified disease activity index (SDAI), and 28-joints disease activity score with C-reactive protein (DAS28-CRP), respectively. Disease activity indices’ scores after BR demonstrated significantly higher in the BI-F group than in the IB-R group. BRR was 92.6%, 92.8%, and 86.5%, while BFR was 71.3%, 71.3%, and 13.8% when indexing CDAI, SDAI, and DAS28-CRP, respectively. Conclusions: Targeting CDAI and SDAI remission prior to BR contributes to a stable clinical course.
Functionalization of Photosensitized Silica Nanoparticles for Advanced Photodynamic Therapy of Cancer
Authors: Prieto-Montero Ruth , Prieto-Castañeda Alejandro , Katsumiti Alberto , Cajaraville Miren P. , Agarrabeitia Antonia R. , Ortiz María J. , Martínez-Martínez Virginia
Published: June 2021

BODIPY dyes have recently raised attention as potential photosensitizers. In this work, commercial and novel photosensitizers (PSs) based on BODIPY chromophores (haloBODIPYs and orthogonal dimers strategically designed with intense bands in the blue, green or red region of the Visible spectra and high singlet oxygen production) were covalently linked to mesoporous silica nanoparticles (MSNs) further functionalized with PEG and folic acid (FA). MSNs of approximately 50 nm in size with different functional groups were synthesized to allow multiple alternatives of PS-PEG-FA decoration of their external surface. Different combinations varying the type of PS (commercial Rose Bengal, Thionine and Chlorine e6 or custom-made BODIPY-based), the linkage design and the length of PEG are detailed. All the nanosystems were physicochemically characterized (morphology, diameter, size distribution and PS loaded amount) and photophysically studied (absorption capacity, fluorescence efficiency, and singlet oxygen production) in suspension. For the most promising PS-PEG-FA silica nanoplatforms, the biocompatibility in dark conditions and the phototoxicity under suitable irradiation wavelengths (blue, green, or red) at regulated light doses (10-15 J/cm2) were compared with PSs free in solution in HeLa cells in vitro.
Prognostic Significance of CKS2 and CD47 Expression in Patients With Gastric Cancer Who Underwent Radical Gastrectomy
Authors: zhou Yang , zeng Jing , zhuang Haoran , zhou wei , wu keyan , shen weigan
Published: June 2021

Objective: To investigate the protein expression levels of cyclin‑dependent kinase subunit 2 (CKS2) and cluster of differentiation (CD) 47 in gastric cancer (GC) and their clinical significances. Methods: A total of 126 GC patients who underwent radical resection were selected as study subjects. Additionally, 32 patients with benign gastric tumor, 42 patients with low-grade intraepithelial neoplasia (LGIEN), and 49 patients with high-grade intraepithelial neoplasia (HGIEN) who underwent surgery were selected as the control groups. Immunohistochemistry was used to detect the expression of CKS2 and CD47 in surgical specimens. We statistically analyzed the clinical significance of the expression of the two factors. Results: (1) The positivity rates for CKS2 in benign gastric tumor tissue, LGIEN tissue, HGIEN tissue, and GC tissue gradually increased, i.e., 6.3% (2/32), 30.9% (13/42), 38.8% (19/49), and 60.3% (76/126), respectively, and the positivity rates for CD47 were 18.8% (6/32), 38.1% (16/42), 46.9% (23/49), and 65.9% (83/126), respectively. (2) High expression of CKS2 and CD47 were associated with tumor diameter, Lauren classification, number of lymph node metastases, and TNM stage. In addition, the immunohistochemical scores for CKS2 and CD47 were positively correlated (r=0.625, P=0.000). (3) The median follow-up time of 126 patients was 46.5 months, and the overall survival rate was 40.5% (51/126). Survival analysis showed that compared with that in the CKS2 (-) group, the overall survival rate for patients in the CKS2 (+) group was significantly worse (25.0% vs 64.0%, 2=15.67, P=0.000) and that compared with the CD47 (-) group, the CD47 (+) group had significantly worse overall survival (30.1% vs 60.5%, 2=15.67, P=0.000). (4) The overall survival rates of CKS2(+)CD47(+) group, CKS2(+)CD47(-) group, CKS2(-)CD47(+) group, and CKS2 (-)CD47 (-) group were 20.0%(13/65), 58.3%(7/12), 57.1%(8/14), 65.7% (23/35), respectively, the prognosis of patients in CKS2(+)CD47(+) group was significantly poor. Conclusion: High expression levels of CKS2 and CD47 were closely related to the occurrence of GC and can be used as independent risk factors to assess the prognosis of patients.
Comparison of Physiological Responses and Training Load Between Different CrossFit® Workouts with Equalized Volume in Men and Women
Authors: Toledo Ronam , Dias Marcelo R. , Toledo Ramon , Erotides Renato , Pinto Daniel S. , Reis Victor M. , Novaes Jefferson S. , Vianna Jeferson M. , Heinrich Katie M.
Published: June 2021

The purpose of the present study was to compare heart rate (HR), blood lactate and training load between different CrossFit® workouts, with equalized total volume in men and women. The study included 23 individuals (13 men and 10 women) experienced in CrossFit® training, who performed two workouts with different training types (as many reps as possible - AMRAP and for time) but equalized volume. Measurements of lactate, HR and rating of perceived exertion (RPE) were performed. The results showed that there was no HR interaction between workout time and sex (p = 0.822; η2 = 0.006] and between workout type and sex (p = 0.064, η2 = 0.803). HR significantly differed during each workout type (p <0.001, η2 = 0.621), but not between the two workout types (p = 0.552, η2 = 0.017). Lactate showed no difference between the workout types (p = 0.474, η2 = 0.768), although the training load was higher (p = 0.033, η2 = 0.199) in women when they performed AMRAP. Altogether, HR was not significantly different between training types or sex, while RPE, lactate and training load showed small differences depending on the group (women or men) or workout type (AMRAP or 'for time').
Open-Bundle Structure as the Unfolding Intermediate of Cytochrome c’ Revealed by Small Angle Neutron Scattering
Authors: Yamaguchi Takahide , Akao Kouhei , Koutsioubas Alexandros , Frielinghaus Henrich , Kohzuma Takamitsu
Published: June 2021

The open-bundle structure of cytochrome c’ as an unfolding intermediate was determined by small-angle neutron scattering experiment (SANS). The four-α-helix bundle structure of Cyt c’ at neutral pH was transited to an open-bundle structure (at pD ~13), which is a joint-clubs consisting of four clubs (α-helices) connected by short loops. The compactly folded structure of Cyt c’ (radius of gyration, Rg = 18 Å for the Cyt c’ dimer) at neutral or mildly alkaline pD transitioned to a remarkably larger “open-bundle” structure at pD ~13 (Rg = 25 Å for the Cyt c’ monomer). Cyt c’ adopts an unstructured random coil structure at pD = 1.7 (Rg = 25 Å for the Cyt c’ monomer). Numerical partial scattering function analysis (joint-clubs) and ab initio modelling gave structures similar to the “open-bundle”, which retains the α-helices but loses the bundle structure.
ABCB1 Does Not Require the Side-Chain Hydrogen-Bond Donors Q347, Q725, Q990 to Confer Cellular Resistance to the Anticancer Drug Taxol
Authors: Sasitharan Keerthana , Iqbal Hamzah Asad , Bifsa Foteini , Olszewska Aleksandra , Linton Kenneth
Published: June 2021

The multidrug efflux transporter ABCB1 is clinically important for drug absorption and distribution and can be a determinant of chemotherapy failure. Recent structure data shows that three glutamines donate hydrogen bonds to co-ordinate taxol in the drug binding pocket. This is consistent with earlier drug structure-activity relationships that implicated the importance of hydrogen bonds in drug recognition by ABCB1. By replacing the glutamines with alanines we have tested whether any or all of Q347, Q725 and Q990 are important for the transport of three different drug classes. Flow cytometric transport assays show that Q347A and Q990A act synergistically to reduce transport of Calcein-AM, BODIPY-verapamil and OREGON GREEN-taxol bisacetate but the magnitude of the effect was dependent on the test drug and no combination of mutations completely abrogated function. Surprisingly, Q725A mutants generally improved transport of Calcein-AM and BODIPY-verapamil, suggesting that engagement of the wild-type Q725 in a hydrogen bond is inhibitory for the transport mechanism. To test transport of unmodified taxol, stable expression of Q347/725A and the triple mutant was engineered and shown to confer equivalent resistance to the drug as the wild-type transporter, further indicating that none of these potential hydrogen bonds between transporter and transport substrate are critical for function of ABCB1. The implications of the data for plasticity of the drug binding pocket are discussed.
Sexual Dimorphism in Crowned Lemur Scent-Marking.
Authors: Elwell Emily , Walker David , Vaglio Stefano
Published: June 2021

Primates are traditionally considered to have a poor sense of smell. However, olfaction is important for non-human primates as demonstrated by conspicuous scent-marking behaviours in lemurs. We studied two family groups (N=4) of crowned lemurs (Eulemur coronatus) housed at Colchester and Twycross zoos (UK) by combining behavioural observations and chemical analyses of scent-marks. We recorded observations of olfactory behaviours for 201 h using instantaneous scan sampling. We investigated the volatile compounds of ano-genital odour secretions using solid-phase microextraction and gas chromatography-mass spectrometry. Males scent-marked most frequently, displaying ano-genital marking for allomarking, head marking for countermarking and wrist marking in specific areas of the enclosure. Females displayed ano-genital marking predominantly on feeding devices. We detected a total of 38 volatile components in all male ano-genital scent-marks and 26 in all female samples of ano-genital odour secretions, including a series of esters, aldehydes, ketones, alcohols, terpenes, volatile fatty acids and hydrocarbons that have been identified in odour profiles of other primates. In conclusion, we found sexual dimorphism in crowned lemurs. Male head and wrist marking behaviours might play defensive territorial functions, while ano-genital marking would be related to socio-sexual communication as chemical mate-guarding. Female ano-genital marking might be involved in resource defense.
Beyond Congruence: Evidential Integration and Inferring the Best Evolutionary Scenario
Authors: Nejad Kourki Arsham
Published: June 2021

Molecular methods have revolutionised virtually every area of biology, and metazoan phylogenetics is no exception: molecular phylogenies, molecular clocks, comparative phylogenomics, and developmental genetics have collectively transformed our understanding of the evolutionary history of animals. Moreover, the diversity of methods and models within molecular phylogenetics has resulted in significant disagreement among molecular phylogenies as well as between these and traditional phylogenies. Here, I argue that tackling this multifaceted problem lies in integrating evidence to infer the best evolutionary scenario. I begin with an overview of recent developments in early metazoan phylogenetics, followed by a discussion of key conceptual issues in phylogenetics revolving around phylogenetic evidence and theory. I then argue that integration of different kinds of evidence is necessary for arriving at the best evolutionary scenario rather than the best-fitting cladogram. Finally, I discuss the prospects of this view in stimulating interdisciplinary cross-talk in early metazoan research and beyond.
Prediction of Peak Friction Angle using Photogrammetry and Comparison to Shear Test Results of Metric Scale Rock Fractures
Authors: Uotinen Lauri , Torkan Masoud , Baghbanan Alireza , Hernández Enrique Caballero , Rinne Mikael
Published: June 2021

An accurate understanding of jointed rock mass behavior is important in many applications ranging from deep geological disposal of nuclear waste to deep mining to urban geoengineering projects. The roughness of rock fractures and the matching of the fracture surfaces are the key contributors to the shear strength of rock fractures. In this research, push shear tests with three normal stress levels of 3.6, 6.0, and 8.5 kPa were conducted with two granite samples with artificially induced well-matching tensile fractures with sizes of 500 mm × 250 mm and 1000 mm × 500 mm. The large sample reached on average a -60 % weaker peak shear stress than the medium-sized sample, and a strong negative scale effect was observed in the peak shear strength. The roughness of the surfaces was measured using a profilometer and photogrammetry. The scale-corrected profilometer-based method (JRC) underestimates the peak friction angle for the medium-sized slabs by -27 % for the medium sample and -9 % for the large sample. The photogrammetry-based (Z’2) method produces an estimate with -7% (medium) and +12 % (large) errors. The photogrammetry-based Z’2 is an objective method that consistently produces usable estimates for the JRC and peak friction angle.