bluuebunny/crossref_metadata_2025 huggingface dataset:
ANÁLISIS DE LOS ANTECEDENTES HISTÓRICO-FILOSÓFICOS DE LA “PARADOJA COGNITIVA DE DUVAL”
Authors: D’Amore Bruno , Fandiño Pinilla Martha Isabel , Iori Maura , Matteuzzi Maurizio
Published: December 2016

En un famoso artículo publicado en 1993, Raymond Duval evidenciaba el siguiente hecho: el estudiante puede confundir el objeto matemático O, que está tratando de construir cognitivamente, con una determinada representación semiótica R(O) de dicho objeto. Explicaba que esta confusión se debía a una especie de paradoja inevitable: sólo quien ha construido el objeto O, puede reconocer R(O) como representación de O y no como objeto en sí. Esta reflexión tuvo una gran influencia en los investigadores en los años sucesivos. Pero, varios estudiosos de semiótica, si bien es cierto que no lo dicen con estas mismas palabras, ya habían evidenciado el fenómeno. En este escrito nos proponemos estudiar algunos de ellos.
GESTOS, SINAIS E ESQUEMAS DE APRENDIZES SURDOS NA MULTIPLICAÇÃO
Authors: Peixoto Jurema
Published: December 2016

El reconocimiento de toda suerte de esquemas que respaldan la acción cognitiva de los alumnos pueden auxiliar al profesor en el análisis de las prácticas matemáticas. Este estudio tuvo como objetivo identificar esquemas movilizados por tres alumnos sordos usuarios de la Lengua Brasileña de Señas para el cálculo de la multiplicación, a partir del concepto de esquema de la Teoría de Campos Conceptuales de Gérard Vergnaud y de la tipología de los gestos de David McNeill. Las tareas analizadas mostraron que todos los alumnos presentaron el esquema de correspondencia señal-a-señal o señal-a-dedo coordinado con el conteo, y dos alumnos presentaron el procedimiento de contar a partir de. Sus esquemas articularon simultáneamente señales con gestos aunque los gestos extrapolaron la función de la comunicación y pasaron a integrar la acción cognitiva de estos alumnos.
Grand designs
Authors: Clarke Jenni
Published: December 2016

Jenni Clarke concludes her series on mud play with an investigation of how mud can provide a wonderful material for artworks. Let children take the lead and see where their creativity takes them.
Time to go home
Authors: Harries Judith
Published: December 2016

The third article in this series exploring different times of day looks at the afternoon and all its associated treats and routines. Try ideas for winding down alongside more creative and free play opportunities.
NEW ADVANCES OF THE COMPATIBILITY INDEX “G” IN WEIGHTED ENVIRONMENTS
Authors: Garuti Claudio E.
Published: December 2016

This article addresses the problem of measuring closeness in weighted environments (decision-making environments). This article is relevant because of the importance of having a dependable cardinal measure of distance in weighted environments. A weighted environment is a non-isotropic structure where the different directions (axes) may have different importance (weight) hence, privileged directions exist. In this kind of a structure, it would be very important to have a cardinal reliable index that is able to show how close or compatible the set of measures of one individual is with respect to the group or to any other, or how close one pattern of behavior is to another.  A few common examples of the application of this are the interaction between actors in a decision making process (system values interaction), matching profiles, pattern recognition, and any situation where a process of measurement with qualitative variables is involved.
PRIORITIZATION OF PERFORMANCE MEASURES USING ANALYTIC HIERARCHY PROCESS
Authors: Vachnadze Revaz
Published: December 2016

The purpose of this paper is to provide an integrated approach that prioritizes organizational performance measures and critical success factors towards the strategic objectives and initiatives of a firm. The Analytic Hierarchy Process (AHP) pair-wise comparisons and hierarchic composition technique is used to prioritize the key performance indicators (KPIs) and the key result indicators (KRIs) as well as the critical success factors (CSFs) of the organization within the frame of a single hierarchy. The new model presented in the paper will be more suitable for dealing with the problem than the others which are available. The application of the suggested model will enable staff to more closely align their daily activities to the strategic objectives of the firm.  The suggested approach allows for a wide applicability to different types of organizations (business, nonprofit, public) and its use could significantly improve resource allocation and the overall performance in organizations.
Five Papers Presented at ISAHP 2014 are published in the International Journal of Production Economics
Authors: Karpak Birsen
Published: December 2016

Eleven papers, out of 91 submitted,  presented at the 13th International Symposium on the Analytic Hierarchy Process (ISAHP), held in Washington DC, USA, from  June 29-July 2, 2014 were selected as candidate papers for the International Journal of Production Economics (IJPE) by the guest editors Drs. Birsen Karpak and Jennifer Shang.  The following 5 out of 11 were able to go through the double blind review process handled by Dr. Peter Kelle, North-American Editor of IJPE, and are published.
MCDM 2017 is in Ottawa, Canada
Authors: Karpak Birsen
Published: December 2016

The 24th International Conference on Multiple Criteria Decision Making will be organized in Ottawa, Canada, from July 10th to July 14th, 2017.
Relational Difference and the Grounds of Comparison: Abdallah Laroui's Critique of Centrism
Authors: Nils Riecken
Published: December 2016

This article examines how the Moroccan historian and intellectual Abdallah Laroui (born in 1933) develops a critique of centrist modes of representing difference. I argue that Laroui himself is situated within hegemonic, hierarchical, and centrist practices of comparison that treat the difference between “Europe” on one hand and “Islam” and “Arab culture” on the other as foundational. Despite being situated in this context, the article argues that Laroui's practice of comparison can be read differently and may open the possibility of the unsettling of such centrist practices. Whereas centrist practices of comparison fixate the relationship between universal and the particular, Laroui points out that any comparative observation stages a historically situated account of the relationship between the particular and the universal. In this way, he reveals that the grounds of comparison are never as flat and homogeneous as centrist practices of comparison imply, and draws attention to the historical-epistemological and political conditions under which difference is relationally produced. Through studying Laroui's discussion of the logic of the concept of history and the concept of modernization in contemporary debates among Arab intellectuals, I analyze the conceptual form of Laroui's version of historicism (Arabic tārīkhāniyya, French historicisme) as a particular form of historicist Marxism. This historicist method challenges what I call centrist architectures of difference produced by centrist modes of representation. It leads Laroui to develop a critical method that I characterize as a situated universalism, steering between relativism and abstract universalism.
Exposição à violência familiar e abuso íntimo em jovens: Que relação?
Authors: Faias Joana , Caridade Sónia , Cardoso Jorge
Published: December 2016

Este estudo analisa a relação entre a exposição à violência familiar e o abuso íntimo juvenil. Para tal recorreu-se à Escala de Sinalização do Ambiente Familiar Natural Infantil e à Escala de Táticas de Conflitos Revisada. Participaram no estudo 505 jovens com uma média de idades de 21.76 (DP = 2.15). Os resultados revelaram altas taxas de prevalência do abuso íntimo, sendo a agressão psicológica a tipologia mais frequente, na perpetração e vitimação (52.3% - 50.4%, respetivamente). Apuraram-se elevadas taxas de violência (80.8%) no contexto familiar, destacando-se a violência emocional (74.3%), seguida do controlo (65.9%), a coerção (34.5%) e por fim, a violência física (16.4%). As análises de associação comprovaram que existe uma relação positiva entre o abuso íntimo e a exposição à violência familiar. Reitera-se, assim, a necessidade de criação de medidas de prevenção e intervenção na violência familiar, atendendo ao seu potencial impacto nas dinâmicas íntimas relacionais.
Representações sociais do usuário de crack para familiares e profissionais de saúde
Authors: Silva Naiara França da , Faro André
Published: December 2016

Este trabalho buscou analisar as representações sociais atribuídas ao usuário de crack na perspectiva de familiares e profissionais de saúde. O estudo foi realizado em quatro Centros de Atenção Psicossocial (CAPS), onde foram entrevistados vinte familiares e trinta profissionais de saúde. Na coleta de dados foram utilizadas associações livres com base na técnica de evocações, organizadas e processadas com o software EVOC. Entre os familiares, as evocações relacionadas às mudanças ocorridas no âmbito familiar decorrentes do uso do crack foram mais significativas. Já entre os profissionais, destacaram-se as concepções voltadas para a necessidade de ajuda e os comportamentos de esquiva na forma de lidar com esses indivíduos. Estes resultados sinalizam importantes desafiosconcernentes a essa temática, tais como as dificuldades dos profissionais de saúde na atuação frente à dependência do crack e a necessidade de incluir a família no cuidado dispensado aos dependentes químicos.
Adolescents’ maps about well-being, distress and selfdestructive trajectories: What’s in their voices?
Authors: Cruz Diana , Narciso Isabel , Sampaio Daniel
Published: December 2016

The mapping of adaptive and maladaptive trajectories in adolescence has been a key concern of developmental psychopathology research. Given the importance of studying adolescents’ own expert views of their experiences, we explored the factors that contribute to the adoption of trajectories characterized by well-being, by distress, and self-destructive trajectories, in a convenience sample of 33 community adolescents (13-21 years old) organized in five focus groups. Adolescents’ mapping of their own trajectories emerged through textual data analysis and was composed mainly of family and individual factors.We proposed a systemic hypothesis to explain how the interactivity between family and individual factors may foster different trajectories: family relational climate and parental emotional support create a context where self-regulation and positive self-esteem are increased. This study contributes to the deeper understanding of developmental trajectoriesand enriches reflections on the conceptualization and implementation of preventive and therapeutic interventions.
Los valores éticos en la Escuela Diocesana de Asistentes Sociales «San Vicente de Paúl» de Pamplona (1960-1985)
Authors: Idareta Goldaracena Francisco
Published: December 2016

El propósito del presente artículo consiste en estudiar el compromiso ético de las profesionales del Trabajo Social en la Escuela Diocesana de Asistentes Sociales «San Vicente de Paúl» de la Archidiócesis de Pamplona. Para ello, analizaremos la importancia que tuvo la Ética en la conformación de la profesión a través de los períodos comprendidos entre 1960 y 1985 utilizando una metodología histórico-sistemática. Durante este intervalo temporal, en España se identifican tres períodos fundamentales (Idareta, Úriz y Viscarret, 2016), mientras que en Navarra únicamente dos. En cada uno de ellos analizaremos el contexto histórico-filosófico y aquellos acontecimientos que pudieron sentar las bases del compromiso ético de las y los profesionales del Trabajo Social.
Teatro breve escolar virreinal hispánico, ilustrado con la edición en apéndice del Encomio sexto al felicísimo Nascimiento de la Virgen, del P. Juan de Cigorondo
Authors: Alonso Asenjo Julio
Published: December 2016

Presentación de la producción de teatro breve escolar virreinal hispánico, siguiendo sus géneros: diálogo, égloga, loa, encomio, decuria, entremés y, en forma parateatral: mojiganga, danza y baile, juego, vejamen. En apéndice se edita el texto de un encomio de Juan de Cigorondo.
La función evangelizadora del teatro breve en la Nueva España del siglo XVI
Authors: Aracil Varón Beatriz
Published: December 2016

Concebido como instrumento eficaz en la labor de cristianización de la población indígena, el teatro evangelizador fue el primer producto cultural plenamente mestizo de la Nueva España. Para desarrollarlo, los misioneros (en especial franciscanos) adaptaron a menudo al contexto americano formas dramáticas breves de la tradición peninsular, integradas en marcos celebrativos más amplios cuyas características fueron variando a lo largo del siglo XVI de acuerdo, por un lado, a las diversas etapas del proceso evangelizador y, por otro, a las necesidades concretas de las distintas zonas del virreinato. El presente artículo aborda algunas de esas formas de teatro breve a partir de la funcionalidad que estas adquirieron en los distintos tipos de eventos de los que formaron parte a lo largo de ese primer siglo de la colonia.
Monarquía y montaje en las loas de Sor Juana
Authors: Hernández Araico Susana
Published: December 2016

La alabanza de la monarquía resalta de modo significativo en la trayectoria literaria de Sor Juana desde su primer poema publicado preconventualmente hasta un texto mencionado (aún no encontrado) en la Fama póstuma. El doble montaje de sus siete loas a los monarcas –escenificación virreinal y publicación en España– está estrechamente vinculado a la ubicación de los virreyes dentro de la política de la corte madrileña.
Teatro breve, regalo de Sor Juana a los años de los condes de Galve
Authors: Rivera Krakowska Octavio
Published: December 2016

De entre la vasta producción para la escena de Sor Juana Inés de la Cruz, las loas cortesanas de su teatro breve han sido las menos estudiadas, a excepción, quizá, de la loa a la comedia Los empeños de una casa y la atribuida a Amor es más laberinto. En el presente trabajo se revisan dos de estas loas, las compuestas para los cumpleaños del virrey conde de Galve y de su esposa Elvira de Toledo. Me permito integrar información sobre las loas que se encuentra dispersa en varios textos, hacer algunas observaciones sobre la edición de estas loas en la Obra completa de Sor Juana a cargo de Alfonso Méndez Plancarte y Alberto G. Salceda, y anotar ciertas particularidades de su representación teatral.
Dos ejemplos del teatro cómico breve hispanofilipino: el Entremés del envidioso y el Sarao agitanado entre ocho hombres y mujeres (Manila, 1677)
Authors: Zugasti Miguel
Published: December 2016

Tras una breve aproximación a la presencia del teatro escrito en español en Filipinas durante el siglo XVII, el artículo se centra en el libro-relación de la Sagrada fiesta, tres veces grande (Manila, 1677), que contiene un total de tres comedias, dos loas, un entremés y un sarao. A continuación se ofrece la edición crítica y anotada del Entremés del envidioso y el Sarao agitanado entre ocho hombres y mujeres, textos que habían permanecido en un olvido casi absoluto desde 1677 hasta hoy.
Propuesta de herramienta para la aplicación de la ingeniería de menú en restaurantes de hoteles all inclusive
Authors: García Pulido Yadrián Arnaldo , Medina León Alberto Arnaldo , Frías Jiménez Roberto Argelio , González Arias Mahé
Published: December 2016

La investigación se desarrolló con el objetivo de analizar el comportamiento de los platos dentro de la carta menú de un restaurante hotelero, y así contribuir a la mejora de la oferta gastronómica del mismo. Las principales técnicas y herramientas que sirvieron de soporte para la obtención de los resultados fueron la ingeniería de menú, mediante una modificación de la matriz MUTI, técnicas de merchandising y Microsoft Excel para la automatización de la herramienta propuesta. Todas estas herramientas estuvieron apoyadas en consultas de documentos de la instalación y control de comandas de los meses de octubre y noviembre de 2014 en el restaurante, definidas como fuentes de información primaria. Como resultado de la investigación se propone una herramienta automatizada para la realización de la ingeniería de menú, basada en el costo y popularidad de los platos. La herramienta propuesta realiza la clasificación de los platos a partir de su ubicación en nueve cuadrantes, determinados por los límites definidos para el costo y la popularidad. Se determinó el comportamiento de cada producto, y se formularon un conjunto de acciones de mejora a la gestión actual de la oferta gastronómica.
El consumo mediático de los estudiantes del Grado de Periodismo ¿Uso lúdico o profesional?
Authors: Redondo Marta , Campos-Domínguez Eva , Vicente-Mariño Miguel
Published: December 2016

El consumo mediático de los jóvenes es un indicador interesante para anticipar tendencias de uso de los medios de comunicación. Los estudiantes universitarios del área de la comunicación son un público especialmente atractivo para explorar estas preferencias. A partir del diagnóstico sobre el consumo mediático de los estudiantes del Grado de Periodismo de la Universidad de Valladolid (España) realizado mediante el método de la encuesta, se celebraron tres grupos focalizados con el fin de detectar patrones dominantes de comportamiento en su relación con los medios, así como indagar en sus motivaciones y valoraciones respecto a la profesión periodística. Los resultados ponen en evidencia la centralidad de Internet en su dieta mediática, un espacio en el que convergen los medios convencionales y las redes sociales digitales. La progresiva especialización adquirida durante la formación universitaria convierte a estos estudiantes en un público crítico con su propio consumo, capaz de detectar fortalezas y debilidades en el ecosistema mediático.
Tipología de los cibermedios periodísticos: bases teóricas para su clasificación
Authors: Salaverría Ramón
Published: December 2016

Desde su aparición en los años 1990, los medios periodísticos digitales han experimentado un proceso de asentamiento y diversificación. Como consecuencia, la fértil clasificación de los cibermedios se ha hecho cada vez más rica y compleja. A partir de una revisión de las tipologías de medios, este artículo propone bases teóricas para la distinción de los cibermedios respecto de los medios anteriores y, sobre todo, para la diferenciación de los distintos tipos de cibermedios entre sí. Con tal fin, se proponen nueve criterios clasificadores: 1) plataforma, 2) temporalidad, 3) tema, 4) alcance, 5) titularidad, 6) autoría, 7) enfoque, 8) finalidad económica y 9) dinamismo.
Las estrategias de los periodistas para la construcción de marca personal en Twitter: posicionamiento, curación de contenidos, personalización y especialización
Authors: López-Meri Amparo , Casero-Ripollés Andreu
Published: December 2016

La marca personal del periodista se ha convertido en un valor clave para ganar prestigio y hacer frente a la crisis del sector. Los medios sociales contribuyen a construir la identidad digital del periodista, estrechando lazos con sus seguidores y ganando autonomía respecto a sus medios. El objetivo de esta investigación es identificar las estrategias que siguen los periodistas para crear o reforzar su marca personal en Twitter. La metodología empleada se basa en entrevistas en profundidad a 15 periodistas españoles de distintos perfiles y roles profesionales. Los resultados permiten identificar y conceptualizar las cuatro estrategias básicas que utilizan para moldear la imagen que proyectan ante su audiencia social. Estas estrategias son el posicionamiento, la curación de contenidos, la personalización y la especialización. Este estudio también permite establecer las principales habilidades y recursos asociados a cada estrategia. Asimismo, se detecta una visión optimista respecto a las ventajas que genera tener marca personal en Twitter. Al respecto, se han identificado tres grandes modalidades de oportunidades: las profesionales, las asociadas a la audiencia y las institucionales.
CONHECIMENTO, COOPERAÇÃO, INSTITUIÇÕES E REPUTAÇÃO: RECURSOS RELEVANTES PARA LOCALIZAÇÃO DE EMPRESAS EM UM PARQUE TECNOLÓGICO?
Authors: Salume Paula Karina , Guimaraes Liliane Oliveira , Versiani Ângela França
Published: December 2016

O presente artigo tem por objetivo analisar o papel dos recursos - conhecimento, cooperação, instituições e reputação - na decisão pela instalação de empresas em um parque tecnológico. Adotou-se como arcabouço teórico a teoria da dependência de recursos e visão baseada em recursos (VBR). Optou-se, como percurso metodológico, pela aplicação de questionário estruturado a dezoito empresas do BH-TEC, obtendo-se quinze respostas, utilizando como variáveis os recursos: conhecimento, cooperação, instituições e reputação (Hoffmann, 2002). O BH-TEC foi criado em 2005 e trata-se de um condomínio que abriga atividades de pesquisa e desenvolvimento voltadas para acelerar as atividades de inovação tecnológica nas empresas. O instrumento de coleta de dados utilizado foi o do estudo de Neckel, Hoffmann e Schoreder (2010), que adaptaram o instrumento inicialmente construído por Hoffmann (2002). Hoffmann (2002) definiu teoricamente os recursos conhecimento, cooperação, instituições e reputação, adotados neste estudo. Identificou-se que o acesso aos recursos “conhecimento”, “instituições” e “reputação” são reconhecidos pelos participantes do parque tecnológico, como importantes para a decisão de instalação no parque. No entanto, constatou-se baixo nível de cooperação interfirmas. Por fim, parece que a decisão pela instalação no BH-TEC está relacionada, positivamente, à existência de recursos estratégicos, já que 87% concordam que a localização no BH-TEC oferece a elas acesso privilegiado a recursos, tais como conhecimento, tecnologia, mão de obra, entre outros.
INTERNACIONALIZAÇÃO DE MICRO, PEQUENAS E MÉDIAS EMPRESAS: UMA AVALIAÇÃO SOBRE O PROCESSO DECISÓRIO ESTRATÉGICO
Authors: Zica Roberto Marinho Figueiroa , Gonçalves Carlos Alberto , Martins Henrique Cordeiro
Published: December 2016

Com o aumento da competição das empresas por novos mercados e a manutenção das posições conquistadas nos nichos em que atuam, os executivos têm buscado formas de atuar em mercados ainda pouco explorados, bem como refinar modelos de gestão já utilizados, de modo a superar os desafios impostos. Em âmbito mundial, esse aceleramento da competição estimula a adoção de novas ferramentas de gestão, ações de exploitation e exploration, a flexibilização de barreiras para produtos e serviços, a customização de bens e a melhor interface com os novos mercados consumidores. Com o acesso viabilizado aos mercados internacionais, determinados tipos de empresas optam pela estratégia de expandirem suas operações a outros países, o que pode ocorrer em várias formas diferentes, podendo se constituir como a maior dimensão do processo contínuo de estratégia. Embora a internacionalização seja historicamente associada a empresas multinacionais, tendências mais recentes sugerem que o mercado internacional está cada vez mais povoado por micro, pequenas e médias empresas. A questão proeminente para este trabalho é a compreensão sobre quais razões motivam ou desmotivam os empresários de pequenos negócios a expandirem suas operações a outros países e, sobretudo, como ocorre o processo desta decisão na ação de internacionalizar seus negócios.
Is it beneficial to the state to provide insulin-treated diabetic patients with public funds for self-monitoring blood glucose?
Authors: Popovich Larisa Dmitrievna , Shestakova Marina Vladimirovna , Potapchik Elena Georgievna , Mayorov Alexander Yur'evich , Vikulova Olga Konstantinovna
Published: December 2016

Background.In Russia, the prevalence of diabetes continues to increase with the growing diabetes epidemic. In recent years, the paradigm of diabetes treatment has been changing, with patients increasingly becoming equal participants in the treatment process, through the introduction of self-monitoring blood glucose (SMBG). Several clinical studies have demonstrated a positive relationship between SMBG and the decline of the epidemiological and economic burden of diabetes. At present, the procurement of public funds for SMBG is below the specified level in Russia.
Aims.To investigate the potential macroeconomic benefits of public health resource allocation and the use of planned state investments to fund SMBG in insulin-treated diabetic patients.
Materials and methods.This study was conducted with data from insulin-treated diabetic patients. The epidemiological burden of this cohort was determined by the following indicators: the number of patients and the incidence of complications resulting from diabetes, disability, mortality, age and sex. The economic benefits were evaluated by the implementation of two measures: (1) procurement of public funds for the purchase of means for SMBG in patients with insulin-treated diabetes and (2) the use of highly accurate blood glucose metres. To evaluate economic burden, the epidemiological burden was translated into monetary terms using cost-of-illness. Economic benefits were defined as reductions in economic burden.
Results.The economic benefits of public-funded blood glucose test strips for insulin-treated diabetic patients exceeded the required additional investments for their purchase by 1.5 fold. A significant reduction in the inaccuracy of blood glucose metres from 20% to 10% may reduce the economic burden by 9.36 billion RUB. The combined state benefits from the implementation of both measures would significantly decrease the economic burden of diabetes to 29.2 billion RUB.
Conclusions. Increased procurement of public funds for SMBG in insulin-treated diabetic patients would bring economic benefits that far exceed the required investments.
Guidelines for the diagnosis and treatment of testosterone deficiency (hypogonadism) in male patients with diabetes mellitus (Draft)
Authors: Melnichenko Galina Afanas'evna , Shestakova Marina Vladimirovna , Rozhivanov Roman Viktorovich , Terehova Anna Leont'evna , Zilov Alexey Vadimovich , Ladygina Daria Olegovna , Kurbatov Dmitriy Gennad'evich
Published: December 2016

Hypogonadism in male patients is defined as a decrease in the serum testosterone level; it is associated with specific symptoms and/or signs (see the detailed description below). It is a common complication in diabetes mellitus. The guidelines do not review all disorders leading to the development of hypogonadism but focus on options for the treatment of hypogonadism, which is generally observed in male patients with diabetes. In the literature, data on the prevalence of hypogonadism in patients with diabetes are available. In the section on diagnostics, the medical history of patients with hypogonadism and diabetes, including the necessary methods for physical and laboratory inspection. Risk factors for and the clinical consequences of hypogonadism are separately considered. In the section on treatment options, variations in treatment using various androgenic therapeutic agents based on patients requirements, conservation of their reproductive function, and their risk factors are provided. Special attention is given to indications of, contraindications of and risk factors for androgenic therapy in male patients with diabetes, particularly those in their advanced age. The principles of the clinical monitoring are developed. The favourable effects of androgenic therapy for hypogonadism in male patients with diabetes are shown.
Evolution of biliopancreatic diversion in the treatment of morbid obesity and type 2 diabetes mellitus
Authors: Bordan Natalya S. , Yashkov Yuriy I.
Published: December 2016

The prevalence of morbid obesity is on the rise. Surgical intervention for the treatment of morbid obesity has been shown to provide high metabolic efficiency, acquiring a special role in the treatment of type 2 diabetes mellitus. Various surgical procedures are used in treating morbid obesity. These include gastric-bypass surgery and biliopancreatic bypass diversion (BPD), each with various advantages of its own. In recent years, BPD (also referred to as the Scopinaro procedure) has evolved and been modified into the single anastomosis duodeno-ileal (SADI) procedure. Like other types of BPD, the SADI procedure effectively reduces excess body weight and promotes normalisation of carbohydrate and lipid metabolism, leading to a reduced frequency of insulin therapy and use of antidiabetic drugs. The potential benefits of the procedure include reduced operative time and a reduced incidence of internal hernias. Studies have also shown that the SADI procedure results in fewer early and late post-operative complications. Given the effectiveness of the procedure, it is necessary to increase the number and duration of observations made to enable further insight into the long-term efficacy and use of the SADI procedure.
Lipid profile and markers of vascular inflammation in patients with stable angina in the presence and absence of type 2 diabetes mellitus
Authors: Petelina Tatiana I. , Musikhina Natalia A. , Gapom Liudmila I. , Емеneva Irina V. , Gorbatenko Elena A.
Published: December 2016

Background. The mechanisms underlying the close relationship between diabetes mellitus (DM) and coronary artery disease (CAD) have not been fully understood. The pathophysiological processes of vascular inflammation that accelerate and enhance the development of atherosclerotic vascular lesions and their complications warrant further study.
Aims. To compare lipid profiles and inflammatory markers in patients with CAD and stable angina in the presence and absence of type 2 DM.
Materials and methods. A total of 169 patients were examined: Group 1 included 123 patients with CAD but without DM; Group 2 consisted of 46 patients with CAD and DM. The biochemical parameters were estimated before coronary angiography.
Results. The lipid profile in both groups of patients revealed elevated levels of atherogenic markers (TС, LDL, VLDLP and TG). Patients in Group 2 had significantly increased levels of vascular inflammatory markers (hs-CRP, homocysteine, IL-1), TNF-, MMP-9 and endothelin-1 compared to those in Group 1.
Conclusions. Our results indicate that the vascular inflammatory response was more pronounced in patients with CAD and DM and that they have an increased risk of developing adverse vascular complications.
Diagnostic value of islet autoantibody assays practised in Russia. 1. Classic immunofluorescence islet cell antibody assay, immunoradiometric glutamic acid decarboxylase antibody assay, and ELISA tyrosine phosphatase antibody and insulin antibody assays.
Authors: Timofeev Alexei V. , Gorst Ksenia A. , Uvarov Valentin Y. , Pronina Ekaterina A. , Vitebskaya Alisa V. , Popovich Anastasiya V. , Tiulpakov Anatoliy N. , Zubkova Natalia A. , Gioeva Olesya A. , Tikhonovich Yulia V. , Ilin Alexander V. , Latyshev Oleg Y. , Okminjan Goar F. , Kabolova Ksenia L. , Kanokova Julianna A. , Zhuleva Leokadia Y. , Koltunov Igor E. , Petriaikina Elena E. , Rybkina Irina G. , Garyaeva Irina V. , Guguchia Salome L. , Shimarova Angelina B. , Bullikh Artiom V. , Kolomina Irina G. , Evsyukova Evgenia A. , Bukin Sergei S. , Egarmina Natalia N. , Arbatskaya Natalia Y. , Yanovskaya Elina Y. , Popenko Vladimir I. , Arkhipkin Alexander A.
Published: December 2016

Objective. To estimate performance characteristics and diagnostic value of immunofluorescent islet cell antibody (ICA) assay, immunoradiometric glutamic acid decarboxylase antibody (GADA) assay, and ELISA tyrosine phosphatase IA-2 antibody (IA-2A) and insulin antibody (IA) assays.Research Design and Methods. Antibodies were tested in 438 children and adolescents with newly diagnosed diabetes mellitus (DM) type 1, and in 891 subjects without DM type 1. ICA were determined by the classic indirect immunofluorescent method recommended by the Juvenile Diabetes Foundation International, GADA were determined with the Immunotech IRMA Anti-GAD kit, and IA-2A and IA were determined with Medizym Anti-IA2 and Orgentec Anti-Insulin ELISA kits, respectively. Sensitivity (Se), specificity (Sp), positive predictive value (PPV) and negative predictive value (NPV) of the tests were estimated with contingency tables. Diagnostic accuracy was estimated from areas under receiver operating curves (AUC).Results. ICA test was of the greatest diagnostic value (Se=88%, Sp=96%, PPV=96%, NPV=94%, AUC=0,94), followed by IA-2A (Se=66%, Sp=98%, PPV=98%, NPV=59%, AUC=0,82) and GADA (Se=73%, Sp=84%, PPV=75%, NPV=83%, AUC=0,79). IA test exhibited a very low Se (4,3%) and lacked diagnostic accuracy (AUC=0,5).Conclusions. We recommend to use ICA, IA-2A and GADA tests surveyed in our study for diagnosis of DM type 1 and differential diagnosis of DM. We don’t recommend IA testing with an Orgentec Anti-Insulin ELISA kit for usage in clinical practice.
Women's experience and attitudes towards menopause and health: descriptive research
Authors: Gregorin Jožefa , Ramšak Pajk Jožica
Published: December 2016

Introduction: The physiological changes in hormonal levels occurring during perimenopause and postmenopause may affect the health of women. The purpose of the research was to explore the views and attitudes of women of this stage towards menopause, health, healthy lifestyle and some aspects of information regarding menopause. Methods: The study was based on a quantitative and qualitative approach. A semi-structured questionnaire (Cronbach α = 0.813) was used as a research instrument. The open question was interpreted by a qualitative method. A random systematic sample consisted of one hundred female patients, aged 45 to 60 years, attending a private healthcare institution. The survey was conducted in October 2014. The data collected were processed with the software Microsoft Excel and SPSS version 20.0. Results: The self-reported health status of the respondents was good (57.3 %) or very good (22.3 %). The most commonly cited symptoms included hot flushes and night sweats (x̅ = 2.73), sleep problems (x̅ = 2.8), and mental and physical exhaustion (x̅ = 2.70). Information from nurses was never sought by 57.6 % and occasionally by 9.8 % of the respondents, although the interviewees expressed the need for more comprehensive information on the subject. The identified subcategories include a positive attitude and self-confidence, support of the environment, consumer health information and healthy lifestyle. Discussion and conclusion: The research participants have a positive attitude to health, they are aware that there is much they can do to maintain and improve their health. As they also expressed the need to be better informed, the scope of nurses' work in referential out-patient clinics may be extended to menopausal counselling. However, more research on this topic needs to be undertaken.
Pogostost in značilnosti nasilja nad zdravstvenimi delavci na področju nujne medicinske pomoči in psihiatrije
Authors: Bojić Matej , Bole Urban , Bregar Branko
Published: December 2016

Uvod: Nasilje pacientov nad zdravstvenimi delavci je ena izmed najbolj perečih težav, s katerimi se soočajo zdravstveni delavci. Namen raziskave je bil proučiti pojavnost ter oblike nasilnih vedenj, ki so jim izpostavljeni zdravstveni delavci na področju psihiatrije in nujne medicinske pomoči.

Metode: Raziskava je temeljila na neeksperimentalni kvantitativni metodi z nenaključnim priročnim vzorcem. Uporabljen je bil strukturirani vprašalnik Perception of Prevalence of Aggression Scale. Sodelovalo je 197 anketirancev. Raziskava je potekala od junija do oktobra 2015. Podatki so bili obdelani z deskriptivno statistiko, s faktorsko analizo – z metodo poševne rotacije OBLIMIN, z Mann-Whitneyevim testom in s Kruskal-Wallisovim testom.

Rezultati: Zaposleni v psihiatriji so pogosteje kot ostali anketiranci soočeni z manj ogrožajočim vedenjem (U = 2092,00, p = 0,008) in ogrožajočim vedenjem (U = 1685,50, p = 0,000). Anketirani z nižjo izobrazbo in zaposleni v izmenah so tisti, ki so nasilju bolj izpostavljeni. Ženske so v primerjavi z moškimi pogosteje soočene s spolnim nasilnim vedenjem (U = 3962,00, p = 0,033). Za obvladovanje nasilnega vedenja so anketirani nezadostno usposobljeni (x = 2,8, s = 1,186).

Diskusija in zaključek: Zaposleni v psihiatričnih bolnišnicah in enotah nujne medicinske pomoči se v raziskavi pogosto srečujejo z nasiljem. Potrebne bi bile raziskave, ki bi proučile povezanost usposabljanja s področja obvladovanja nasilnega vedenja pacientov na pojavnost nasilja nad zdravstvenimi delavci.
Lastnosti mentorja in mentoriranca z njunih medsebojnih vidikov: opisna raziskava mnenj dijakov, študentov in mentorjev
Authors: Babuder Dragan
Published: December 2016

Uvod: Lastnosti mentorja so za odnos med mentorjem, dijakom in študentom zdravstvene nege zelo pomembne. Namen raziskave je bil ugotoviti, katere lastnosti mentorjev so pomembne z vidika dijakov in študentov zdravstvene nege, in obratno, katere lastnosti mentorirancev, tj. dijakov oz. študentov, so pomembne z vidika mentorjev. Metode: Uporabljena je bila kvantitativna deskriptivna metoda raziskovanja. S spletnim anketnim vprašalnikom je bil anketiran 201 anketiranec, od tega 50 dijakov srednje zdravstvene šole (3. in 4. letnik), 97 študentov prve stopnje zdravstvene nege (2. in 3. letnik) ter 54 mentorjev v kliničnem okolju. Uporabljena je bila deskriptivna statistika, test hi-kvadrat ter metoda analize variance oz. analiza povprečij. Rezultati: Ugotovljeno je bilo, da mentorji menijo, da odnos med mentorirancem in mentorjem ni odvisen od mentorjeve starosti. Komunikacija je pomembna vsem trem skupinam anketirancev. Medsebojno spoštovanje je enako pomembno dijakom, študentom in mentorjem. Mentorjem je poleg dijakovega oz. študentovega spoštljivega odnosa najpomembnejše, da se dijak oz. študent zaveda svojih nalog in zadolžitev (x = 4,6). Najbolj zaželena lastnost mentorja je, da si vzame čas (x = 4,7) za dijaka oz. študenta ter da je organiziran in dostopen. Diskusija in zaključek: Med raziskovalnimi skupinami je opaziti razlike v dojemanju lastnosti in vrlin mentorjev. Vsem raziskovalnim skupinam je pomembna mentorjeva sposobnost komunikacije ter ustvarjanja kreativnega okolja.
Agility, acceleration, speed and maximum speed relationship with age factor in soccer players
Futbolcularda yaşa bağlı çeviklik, ivmelenme, sürat ve maksimum sürat ilişkisi
Authors: Sever Ozan , Arslanoğlu Erkal
Published: December 2016

The aim of study was to investigate age-related agility, acceleration, speed and maximum speed relationships in soccer players. Study consisted of 125 young football players aged between 14 and 18 from Karabükspor youth and reserve team who were measured for 30m speed,10m acceleration, 20m maximum speed, and T-Agility tests. The test values of players decreased with age as expected. All performance tests correlated significantly but coefficients of determination (r2) between agility test and all other tests were low. Acceleration and other tests except 30m speed also were low. There were no differences in age groups in terms of correlation between tests. Because of low coefficients of determination, it could be said that maximal speed, acceleration, agility were correlated by chance and were different components of physical performance so different training sessions should be planned for each physical abilities. ÖzetÇalışmada futbolcuların sürat, çeviklik, ivmelenme ve maksimum sürat becerilerinin yaşa bağlı değişimi ve birbirleri ile ilişkisi araştırılmıştır. Karabükspor altyapısı, A2 takımında 14-18 yaş aralığındaki 125 sporcu katılmıştır. Sporcuların 10m ivmelenme, 30m sürat ve T-Çeviklik ve 20 m maksimum sürat ölçümleri yapılmıştır. İstatistiksel analiz SPSS 19 programında yapılıp, 0,05 anlamlılık değeri olarak kabul edilmiştir. Sporcuların, çeviklik, ivmelenme, sürat ve maksimum sürat ölçüm süreleri yaş ile birlikte düşüş göstermektedir. En belirgin düşüş çeviklik testinde ortaya çıkmıştır. Tüm ölçümler arasında pozitif doğrusal ilişki vardır. Bu ilişki yaş faktörü ile incelendiğinde anlamlılık devam etmiştir. Fakat açıklayıcılık katsayılarına(r2) bakıldığında çeviklik ile diğer tüm ölçümler, ivmelenme ile 30 metre sürat süresi hariç tüm ölçümlerde düşük ilişki söz konusudur. Yaşa bağlı değişimde çevikliğin, doğrusal koşulara göre daha belirgin geliştiği ortaya çıkmıştır. Açıklayıcılık katsayısının düşük bulunması futbolcuların çeviklik, ivmelenme, sürat becerilerinin birbirleri ile güçlü ilişkisinin olmadığını göstermektedir. Bu fiziksel becerilerin birbirlerinden ayrı özellikler olduğu, antrenman planlamalarının bu beceriler ayrı ele alınarak yapılmasının faydalı olacağı düşünülmektedir.
KCTD Hetero-oligomers Confer Unique Kinetic Properties on Hippocampal GABABReceptor-Induced K+Currents
Authors: Fritzius Thorsten , Turecek Rostislav , Seddik Riad , Kobayashi Hiroyuki , Tiao Jim , Rem Pascal D. , Metz Michaela , Kralikova Michaela , Bouvier Michel , Gassmann Martin , Bettler Bernhard
Published: December 2016

GABABreceptors are the G-protein coupled receptors for the main inhibitory neurotransmitter in the brain, GABA. GABABreceptors were shown to associate with homo-oligomers of auxiliary KCTD8, KCTD12, KCTD12b, and KCTD16 subunits (named after their T1 K+-channel tetramerization domain) that regulate G-protein signaling of the receptor. Here we provide evidence that GABABreceptors also associate with hetero-oligomers of KCTD subunits. Coimmunoprecipitation experiments indicate that two-thirds of the KCTD16 proteins in the hippocampus of adult mice associate with KCTD12. We show that the KCTD proteins hetero-oligomerize through self-interacting T1 and H1 homology domains. Bioluminescence resonance energy transfer measurements in live cells reveal that KCTD12/KCTD16 hetero-oligomers associate with both the receptor and the G-protein. Electrophysiological experiments demonstrate that KCTD12/KCTD16 hetero-oligomers impart unique kinetic properties on G-protein-activated Kir3 currents. During prolonged receptor activation (one min) KCTD12/KCTD16 hetero-oligomers produce moderately desensitizing fast deactivating K+currents, whereas KCTD12 and KCTD16 homo-oligomers produce strongly desensitizing fast deactivating currents and nondesensitizing slowly deactivating currents, respectively. During short activation (2 s) KCTD12/KCTD16 hetero-oligomers produce nondesensitizing slowly deactivating currents. Electrophysiological recordings from hippocampal neurons of KCTD knock-out mice are consistent with these findings and indicate that KCTD12/KCTD16 hetero-oligomers increase the duration of slow IPSCs. In summary, our data demonstrate that simultaneous assembly of distinct KCTDs at the receptor increases the molecular and functional repertoire of native GABABreceptors and modulates physiologically induced K+current responses in the hippocampus.

SIGNIFICANCE STATEMENTThe KCTD proteins 8, 12, and 16 are auxiliary subunits of GABABreceptors that differentially regulate G-protein signaling of the receptor. The KCTD proteins are generally assumed to function as homo-oligomers. Here we show that the KCTD proteins also assemble hetero-oligomers in all possible dual combinations. Experiments in live cells demonstrate that KCTD hetero-oligomers form at least tetramers and that these tetramers directly interact with the receptor and the G-protein. KCTD12/KCTD16 hetero-oligomers impart unique kinetic properties to GABABreceptor-induced Kir3 currents in heterologous cells. KCTD12/KCTD16 hetero-oligomers are abundant in the hippocampus, where they prolong the duration of slow IPSCs in pyramidal cells. Our data therefore support that KCTD hetero-oligomers modulate physiologically induced K+current responses in the brain.
La ética kantiana vista por Schopenhauer
Authors: González-Mérida Luis
Published: December 2016

A menudo se discute cómo cifrar el alcance de la herencia de Kant en la metafísica de Schopenhauer. Del corazón y sustancia de su Tebas de las mil puertas, la ética, Aramayo (2011) cree oportuno tomarla como una radicalización del formalismo kantiano. A mi juicio, para delimitar qué hay de continuidad, y qué de ruptura, es necesario hacer un examen atento del puente que conduce de uno a otro. En este sentido, la crítica dedicada a Kant en Sobre el fundamento de la moral no ocupa un lugar accidental en su pensamiento único, pues contiene lo que le falta al apéndice crítico de su obra principal respecto al objeto que nos ocupa. Desde el análisis de conceptos hasta las lecturas (proto)genealógicas que se presentan en esta polémica, un mismo propósito subyace: la depuración del concepto de racionalidad práctica como solución a las aporías y los escollos del legado ético kantiano.
Time, Count and Soul in Aristotle. An Interpretation of Physica IV.14, 223a25-26
Authors: Barrionuevo Sergio Javier
Published: December 2016

Aristotle’s study of time in Physics IV.10-14 shows great difficulties, one of these is the link between time and soul made in 223a21-28. This passage was discussed by several modern scholars during the twentieth century. There is no unanimous consensus, but the “realistic interpretation” was widespread during the last century. In this paper I propose to discuss the interpretation of the premise 223a25-26 in Aristotle’s argument about the timesoul link and reject the “realistic interpretation” of this passage whereby the time as count would exist independently of the soul. I intend to show that time’s ‘countable’ feature does not exist independently of the soul, unlike what happen with the ‘sensible’.
Metafísica de la Naturaleza en la filosofía de Spinoza: una interpretación del conatus como primera determinación ontológica de la natura naturata
Authors: Álvarez Montero Daniel
Published: December 2016

El concepto de conatus ha recibido diversas interpretaciones en la obra de Spinoza, y sus mayores controversias residen en la manera en que éste se aplica a ciertos modos de la Naturaleza –en especial, el ser humano–. Problemas como el suicidio, de ese lado, o la estabilidad de ciertas partículas subatómicas, por otro, han parecido poner en entredicho la integridad de este concepto. En este artículo perfilaré una interpretación del mismo que esquiva estas ambigüedades, argumentando que este concepto se presenta en forma eminentemente ontológica y, a su amparo, las principales problemáticas en torno al mismo se tornan espurias.
Las compañías de comercio armado durante el siglo XVII: los proyectos de 1667 y 1668
Authors: Aragon Ruano Alvaro
Published: December 2016

Mucho se ha escrito sobre los proyectos de compañías privilegiadas que tuvieron lugar durante el siglo XVII y parecería que nada más se puede añadir. Sin embargo, documentación inédita existente en el Archivo General de Gipuzkoa sobre un proyecto presentado en 1667 para una compañía de comercio armado y sobre las negociaciones producidas entre 1667 y 1670, permiten profundizar en los factores que provocaron el fracaso de las sucesivas propuestas realizadas durante los reinados de Felipe IV y Carlos II y releer toda la documentación e información ya conocida hasta la fecha. Desde que en 1628, a consecuencia del desastre de Matanzas, se proyectase el establecimiento de una compañía de comercio armado, bajo auspicio real, siguiendo el modelo de otros países como Holanda, Inglaterra o Francia, las diferentes propuestas, a pesar de su fracaso, no fueron meramente archivadas, y en cada nueva tentativa eran revisadas y algunos de sus artículos recuperados, de forma que las experiencias se fueron acumulando y mejorando