bluuebunny/crossref_metadata_2025 huggingface dataset:
Small Animal Review
Authors: Tennant Bryn
Published: May 2013

Introduction

The management of renal disease requires an understanding of the role that parathyroid hormone plays in abnormal mineral metabolism.
Staged, bilateral total hip replacements in a nine-month-old Springer Spaniel
Authors: Rutherford Scott
Published: May 2013

Total hip replacement (THR) is becoming relatively commonplace in the dog. This article describes an unusual case of staged bilateral, cementless THRs in a skeletally immature dog. The decision-making process for this case is reviewed. The article also reviews the indications, complications and prognosis for THR in the dog. The various systems that are commercially available are also briefly described. It is hoped that the reader will have a better understanding of which dogs are candidates for referral for surgery, and that he/she is better prepared to discuss this with owners.
Quantitative Insulin Analysis Using Liquid Chromatography–Tandem Mass Spectrometry in a High-Throughput Clinical Laboratory
Authors: Chen Zhaohui , Caulfield Michael P , McPhaul Michael J , Reitz Richard E , Taylor Steven W , Clarke Nigel J
Published: May 2013

BACKGROUND

Circulating insulin concentrations reflect the amount of endogenous insulin produced by the pancreas and can be monitored to check for insulin resistance. Insulin is commonly measured using immunochemiluminometric assays (ICMA). Unfortunately, differing crossreactivities of the various ICMA antibodies have led to variability in assay results. In contrast, liquid chromatography–tandem mass spectrometry (LC-MS/MS)-based approaches can provide a highly specific alternative to immunoassays.

METHODS

Insulin was extracted from patient serum and reduced to liberate the insulin B chain. Subsequent resolution of the peptide was achieved by LC coupled to triple-quadrupole MS. Selected-reaction monitoring of B-chain transitions was used for quantification. Recombinant human insulin was used as a calibrator and was compared against the National Institute for Biological Standards and Control (NIBSC) reference standard. Bovine insulin and a stable isotopic-labeled (13C/15N) human insulin B chain were used and compared as internal standards.

RESULTS

The LC-MS/MS assay described herein has been validated according to CLIA guidelines with a limit of detection of 1.8 μIU/mL (10.8 pmol/L) and a limit of quantitation of 3 μIU/mL (18.0 pmol/L). A correlation between the LC-MS/MS assay and a US Food and Drug Administration-approved ICMA was completed for patient samples and the resulting Deming regression revealed good agreement. A reference interval for the assay was established.

CONCLUSIONS

A simple, high-throughput, quantitative LC-MS/MS insulin assay traceable to the NIBSC standard has been successfully developed and validated.
Home, Nostalgia, and Memory: The Remedy of Identity Crisis in New Thai Cinema
Authors: Chaiworaporn Anchalee
Published: May 2013

This essay examines how the new-generation directors of New Thai cinema, who started to emerge a few months before the Asian economic crisis in 1997, tend to stick to the Asian values in the representations of their works. On the surface, this generation proved to be a new wave and
a breakup of the Thai film culture, boosting the fame of Thai cinema not only in the local, but also global markets, more than any of the previous generations could do. On the other hand, in their films, they always call for the seeking of the perfect family, home and the longing for the good
old days.
Crouching Tiger Hidden Dragon, Hero, and House of the Flying Daggers: Interpreting Gender Thematics in the Contemporary Swordplay Film -- A View From the West
Authors: Levitin Jacqueline
Published: May 2013

Some 20 years ago, I was doing research for a film on women fighters in liberation struggles. My results were unexpected back home. In North America at the time, the dominant mythology in the women’s movement was that females were non-violent by nature. It was taken for granted
that women favored pacifism and avoided conflict. My interview with a young woman fighter from Zimbabwe was thus shocking. I still recall her phrasing: “If too much time goes by without combat, my little trigger finger is itching to shoot.” She told me she had lost her cousin in
an air attack by the Rhodesian military on their guerrilla army camp in Mozambique. It was a quiet day and her cousin had been braiding her hair. As the planes retreated and the noise subsided, she suddenly realized that her cousin was dead by her side. This young woman fighter was angry.
She wanted revenge.
Nolletti, Arthur, Jr. The Cinema of Gosho Heinosuke: Laughter Through Tears. Bloomington: Indiana University Press, 2005.
Authors: Ehrlich Linda C.
Published: May 2013

Gosho Heinosuke (1902-1982) directed almost 100 films from the late 1920s -- 1968, but only 40 survive. Arthur Nolletti Jr.’s recently released The Cinema of Gosho Heinosuke: Laughter Through Tears offers an insightful appraisal of the work of this important -- and yet too long
overlooked --Japanese film director.
Paul Clark. Reinventing China: A Generation and Its Films. Hong Kong: Chinese University Press, 2005.
Authors: Jacobson Susan
Published: May 2013

Reinventing China: A Generation and Its Films presents a concise history of China’s Fifth Generation filmmakers and their unprecedented impact on Chinese film. Readers of Asian Cinema need no introduction to the Fifth Generation filmmakers: They are those individuals who graduated
from the Beijing Film Academy’s class of 1982, the first class to graduate after the Cultural Revolution years. Clark’s thesis contends that the common life experiences of these individuals, combined with the profound changes that took place in Chinese society between 1966 and
1989, created an environment where both Chinese artists and the Chinese public were ripe for reinvention. Clark argues that the early films of the Fifth Generation helped the Chinese public re-imagine their culture and recent history in ways that had not been possible before.
The Clash of Traditional Chinese Culture: A Personal View on The Day the Sun Turned Cold
Authors: Zhou Jinghao
Published: May 2013

Confucian filial piety was a basic social norm to consolidate family ties in pre-communist China. However, Confucianism was fiercely attacked by communist ideology under the Mao regime. What kind of principle have the Chinese people followed to deal with family relations in the post-Mao
era? The Day the Sun Turned Cold (in Chinese tian guo ni zi ) provides an excellent case study in explaining these questions by demonstrating a complex murder story based on a real-life Chinese criminal case. This film won the Best Film and Best Director awards at the 1994 Tokyo Film Festival.
Li Shaobai: From Pioneer Film Researcher to “Dead Tiger” to Grand Old Mentor of Film Studies
Authors: Lent John A.
Published: May 2013

Li Shaobai has had a distinguished -- at times life changing-- career in China’s film studies. He, Cheng Jihua, and Xing Zuwen produced Zhong Guo Dian Ying Fa Zhan Shi in 1963, the first major history of Chinese cinema and the subject of much criticism leading to all three authors
being severely punished during the “Cultural Revolution.” Li also was responsible for establishing early film research groups, such as the China Film Art Research Center in 1974 and later, the Chinese Film and Television Research Institute under the Academy of Chinese Art. The
latter was the first institution to grant both the masters (in 1982) and Ph. D. (in 1995) degrees in film studies in China, and, as a result, Li Shaobai became the mentor of the first batch of Chinese film researchers. His first MA students were Chen Xihe, Bao Yuheng, Zhong Dafeng, Zhang Aihua,
and Wang Hanchuan; the first two doctoral students at CFTRI were Ding Yaping and Li Daoxing, followed by Shi Chuan. He said today, four Ph. D. programs in film studies exist in Beijing: CFTRI, Beijing Normal University, Beijing Film Academy, and Communication University of China.
Asian Film Research and Me
Authors: Zhen Ni
Published: May 2013

Back in the years in junior middle school in the 1950s, I saw a Japanese film named Geisha . The final shot of the film focuses on the father who is powerless to change his daughter’s fate, and the daughter, being beaten black and blue, has no choice but resume her life in the
geisha’s house. The father immerses himself in knocking the hobnails into the sole and the daughter gradually vanishes deep in the background. As a then-young boy who knew nothing about the outside world, and who could never imagine that he will be engaged in the film industry one day,
I was deeply affected by the ending which vividly reflects the pains and sufferings of the world.
Asian Film Study as an Offshoot of Mass Communication
Authors: Lent John A.
Published: May 2013

My entry into Asian film study probably can be traced to 1964_1965, when I was in the Philippines on a Fulbright scholarship, doing research on mass communications, an end result of which was the first book on Philippine mass communications (1971). In that book, a full chapter was devoted
to film.
Introspection and Reconstruction: Review of the Centennial Celebration of Chinese Cinema and the 2005 Annual Conference of ACSS
Authors: Chuan Shi
Published: May 2013

Chinese Cinema and Asian Cinema in the Context of Globalization: International Conference of the Centennial Celebration of Chinese Cinema,” the conference co-hosted by Shanghai University, Peking University, and Asian Cinema Studies Society, was held at Peking University and Shanghai
University, respectively, from July 6 to 10, 2005. Nearly 200 scholarly papers from 20 countries and regions, including the United States, England, Canada, Japan, Korea, India, Singapore, New Zealand, Taiwan, Hong Kong, and Macau, were accepted and discussed. With as many as 33 interest groups,
the conference becomes another significant event for the conversation between Eastern and Western film scholars after the successful “International Conference of Film Aesthetics and Theoretical Trend” held by Shanghai University in 2004.2 In addition to celebrating the centennial
of Chinese film, the launch of the conference is also related to the rising popularity of Chinese film in academia overseas. Since the 1990s, there is the tendency that film is gradually replacing the traditional art forms, such as novels, to become one of the major tools for the West to observe,
imagine, and even construct the concept of the East. This tendency follows the intensified globalization process, the development of information technology, and the rising of audio-visual media.
The Accidental Scholar
Authors: Berry Chris
Published: May 2013

When I arrived at UCLA in 1981 on an exchange scheme from Leeds University in England, I had just completed a B.A. in Chinese Studies. Although it was as much my fault as anyone else’s, my B.A. had bored me and I had no intention of having anything more to do with China. But when
one UCLA professor after another greeted me with, “Oh, you’re the guy that does Chinese film,” I realized it was not going to be that easy. Asked now to think about how I got into Chinese film and what it was like back then, I realize that my entire career has been a series
of accidents -- lucky and otherwise.
Looking Back
Authors: Semsel George S.
Published: May 2013

“Look around you,” Victor said as we waited for our Pakistani Potatoes and Indonesian Rice in the Foreign Experts dining hall at Youyi Bingyuan, “Everyone you see is writing a book about their experiences in China. And they’re all convinced they’re the
ones who’ve discovered the real China.” I didn’t tell him I was already thinking about it. I didn’t go to China to research Chinese film, not at first. That is what many of my colleagues either do not know or do not understand. Naïve and as ignorant of China as,
unfortunately, most of my colleagues and much of the United States remain, I went out of a growing curiosity.
Chinese Cinema: Exposures, Research, and Change
Authors: Yau Esther C.M.
Published: May 2013

Continuous Transnational Exposures: A Brief Personal Account. In the winter of 1984, an energetic MFA student at UCLA, Mishka Chen, made some duplicate copies of contemporary Chinese films on videocassettes for his schoolmate. He was one of the earliest production graduate students
at UCLA. Not only did he show a superior knowledge of who’s who in official culture, he was active in getting movies from the cultural section of the Chinese embassy in San Francisco that consistently supplied overseas Chinese student associations with new movies coming out from China.
Ada Apa Dengan Indonesia Cinema? (What’s up with Indonesian Cinema?) Interviews with Filmmakers Riri Riza and Rudy Soedjarwo
Authors: Ciecko Anne
Published: May 2013

With the continued visibility and impact of Thai cinema at festivals worldwide, curious programmers are turning their gaze to other Southeast Asian countries. The new energy of contemporary Indonesian filmmaking was recognized with a total of eight shorts and features at the 10th annual
Pusan International Film Festival and eleven films at the 35th International Film Festival Rotterdam… Below are interviews with two more of Indonesia’s most critically acclaimed and commercially successful feature film directors of this generation, Riri Riza and Rudy Soedjarwo.
A Study of the Post-Handover Hong Kong Action Cinema 1997-2007
Authors: Yau Shuk-ting Kinnia
Published: May 2013

The action movie has always been a genre that Hong Kong cinema is proud of. Many symbolic figures of Hong Kong cinema arose from this genre. Examples include Bruce Lee, Jackie Chan, Yuen Woo-ping, John Woo, Jet Li, Johnnie To, and Andrew Lau. Some of them were invited to participate
in Hollywood pictures, and a few of the movies such as Infernal Affairs, were remade into Hollywood versions which achieved box office success and recognition with film awards. Undoubtedly, Hong Kong action movies have received worldwide recognition, fulfilling the dream that Hong Kong filmmakers
have been striving hard to achieve for years.
Social Critiques and Sentimentalism: On Wang Xiaoshuai’s So Close to Paradise
Authors: Gong Haomin
Published: May 2013

As a key figure in the so-called “Sixth Generation” directors in China, Wang Xiaoshuai has attracted considerable attention in academics, both in China and in the West. His first “legal” film — a film that is officially authorized by the state-controlled
filmmaking system in China — So Close to Paradise (Biandan guniang, 1996) deserves special attention. As a transitional film from the “underground” to “in-system” production, this film represents a salient transition in Wang’s filmmaking when he was facing
the imperatives of art, state censorship, and commercialization. In this sense, it is also a locale where investigations of the problematics of Chinese film at the turn of the 21st Century can be fruitfully conducted.
Traveling Bodies: Gender, Nationalism and Diasporic Identity Formation in Gurinder Chadha’s Bhaji on the Beach
Authors: Banerjee Bidisha
Published: May 2013

Gurinder Chadha’s film, Bhaji on the Beach , explores the issues of home, identity, hybridity, and belonging with respect to Indian women in Britain. The film revolves around a group of Indian women ranging from the age of 16 to 60, all members of the Saheli (girlfriend) Women’s
Centre who go on a day-trip to Blackpool, a popular beach resort for working class Britons. This ensemble of characters represents a range of marginalizations experienced by the ethnic women in Britain today.
Song Liling and Cheng Dieyi: An Orientalized Asian and His Native Informant — Comparing M. Butterfly with Farewell My Concubine
Authors: Shi Xiaoling
Published: May 2013

When depicting Asians, both the Asian American play M. Butterfly and the Chinese film Farewell My Concubine utilize Beijing Opera and homosexuality as two selling points to create an enticingly exotic dish to pique the curiosity of Occidental viewers, which makes the two works comparable.
They demonstrate how Orientalism has insinuated itself in the discourse of “Asian minorities living in the West” and “the Orient,” a venture that Sheng-mei Ma claims Edward Said “seldom” undertook and he himself partially pursued in his book Immigrant Subjectivities:
In Asian American and Asian Diaspora Literatures (Ma, 1998:24).
Two Coming-out Shorts Related to India
Authors: Pearson Lyle
Published: May 2013

Two gay shorts shown at the 2007 Seattle International Film Festival had an Indian connection — Kali Maa, a Columbia University project about a mother defending her battered son, shot in the U.S., and Cowboy Forever, a French/Brazilian answer to Brokeback Mountain.
Adapting Japanese Horror: The Ring
Authors: Tsai Peijen Beth
Published: May 2013

The examination of Hollywood remakes of Asian horror films presents the compelling opportunity to analyze the imagination of ghosts and haunting in diverse cultures. In 1998, Ringu, directed by Nakata Hideo, was released to widespread acclaim. Four years later, Gore Verbinski’s
The Ring (2002) was released in the United States. The latter film was criticized as a retelling of the hit Japanese thriller, little more than a Hollywood knock off.
A Space of a Thousand Faces: Spatial Poetics in A Thousand Years of Good Prayers and The Princess of Nebraska
Authors: Nie Jing
Published: May 2013

Wayne Wang (1949- ), the director of A Thousand Years of Good Prayers and The Princess of Nebraska, is a prolific Chinese American film director, who made his name with independent films rooted in Chinese diasporic culture, such as Chan Is Missing (1982) and Eat a Bowl of Tea (1989).
He is probably best known for directing The Joy Luck Club (1993), a film adaptation of Amy Tan’s novel depicting entangled relationships between American-born Chinese women and their native Chinese mothers. A Thousand Years of Good Prayers and The Princess of Nebraska, premiered at the
2007 Toronto International Film Festival, marked Wang’s return to small, intimate filmmaking related to Chinese culture from his Hollywood detour (Maid in Manhattan , 2002; Because of Winn-Dixie , 2005; Last Holiday , 2006).
Spatial Blooms
Authors: Kulper Perry , Fogle Justin
Published: May 2013

‘Spatial Blooms’ (Figures 1 and 2) is research by design work undertaken through the generous support of the University of Michigan’s Taubman College ‘Research Through Making’ grant programme. This article discusses work that explores the possibility of
inscribing indeterminacy and varied temporal logics, borrowed from landscape, into architecture. It foregrounds the potential of an evolving architecture that stimulates relationships that might be generated through its existence – temporally active germinal formations, loaded and ready
to go. Design efforts study this potential using landscape ready-mades; specifically, landscape’s organizational principles, landscape elements and landscape ‘biologies’, as well as their capacities to engender change, enfolded through design. Ultimately, such architecture
would facilitate variable and changing spheres of influence, activated in time. The work trades on the richness of landscapes at cultural, experiential and operational levels, investigating ways in which landscape properties can find their way into architectural speculations. It explores the
cross-pollination of landscape properties into architecture through three specific lenses: (1) developing specific visualization techniques to evolve the work; (2) using language prompts to activate design possibilities; and (3) analogous thinking as a design method. ‘Spatial Blooms’
discusses several relationships to the journal’s theme, ‘Sentient Relic’. It suggests spatial and material formations that exist in various phases, or phase states, oscillating between instructional and visceral forms of communication; it offers the possibility of non-anthropocentric
spatial logics by augmenting perspective as a dominant spatial apparatus and by initiating relationships through non-anthropocentric landscape characteristics; and it explores an alternative architectural approach in relation to the fixed functional or formal relations of architecture based
on typological classification. It is grounded by using ecological thinking as a generative metaphor, suggesting that life might exist somewhere between closed systems and open, shared and active environments. In sum, the work attempts to inscribe alternative temporal logics, change and indeterminacy
into speculative architectural settings to activate habitual spatial practices. It attempts to seduce the unknown and provoke curiosity. As a result, it invokes active spatial participation. It studies this possibility by using ready-made landscape characteristics, analogously. Eventually,
landscape behaviours, or landscape ‘biologies’, will be injected into the visualizations featured in this article. The cultural, disciplinary and experiential durability of landscape plays important roles in exploring the use of landscape ready-mades toward new architectural possibilities.
Out of our hands: Three architectural fantasies for strange and sad ecologies
Authors: West Mark
Published: May 2013

Here is a story told through three architectural fantasies, separated by over a quarter century from first to last. The arc of this story is caught in a strong tension between architecture’s essential optimism and certain dystopic social ecologies. Its story draws upon a personal
narrative in order to give a figure to our collective imagination of the future and our picture of our place in Nature and how these have altered through 30 years of cultural, technological (and personal) change. It wants to know what architecture might be called to do and how it might act
when caught in a diastolic cultural pulse – a dark groping for beauty in an evolving landscape of difficult imagined futures.
Mechanisms of three-dimensional content transfer between the OpenSimulator and the Second Life Grid® platforms
Authors: Sequeira Luis , Morgado Leonel
Published: May 2013

Virtual worlds have been successfully employed as tools for educational, simulation and training use. The ability for users to easily create their own content with simple editing tools has made the Second Life Grid® platform, and its free open source equivalent, OpenSimulator, very
popular. While the Second Life Grid offers more features, stability and a larger user base, cost considerations and some lack of control have led some projects to consider development/deployment exclusively on an OpenSimulator grid. This poses the problem of how to transfer to such a grid
any content that was developed and refined in the Second Life Grid, since the company behind Second Life ®, Linden Lab, does not offer an archival/restore facility for user-generated content. In this article, we analyse some third-party tools that can partially backup and restore some
content and describe a mechanism to automatically capture all content in a whole region of the Second Life Grid and save it to a commonly used file format (Open Archive) that is universally used on OpenSimulator grids, and report on a prototype we developed to implement it with reasonable
results, but also some serious limitations, which are further discussed.
Revealing the Invisible: The Art of Stansfield/Hooykaas from Different Perspectives, Madelon Hooykaas and Claire van Putten (eds), (2010)
Authors: Elwes Catherine
Published: May 2013

1st ed., the Netherlands: Uitgeverij De Buitenkant, 335 pp., ISBN: 978-94-00913-03-8, h/bk, £40/$50
Peter Gidal’s anti-narrative: An art of reprisal reappraised
Authors: McIntyre Steven
Published: May 2013

In this article I will reassess the ideas of artist, intellectual and educator Peter Gidal, who, unlike his similarly positioned contemporaries Laura Mulvey and Peter Wollen, is not well remembered today outside avant-garde film histories and readerships. Throughout the 1970s and 1980s,
in a series of publications through the BFI press, in more artists’ film-focused journals such as Afterimage and Undercut, and, most significantly in the then leading film theory journal Screen, Gidal argued the centrality of the avant-garde, especially a local British expression he
termed ‘structural/materialist’ film. Drawing on previous studies of Gidal by Deke Dusinberre (1976) and D. N. Rodowick (1988), and also the study of intellectual, literary and artistic fields by Pierre Bourdieu (1993), I propose, notwithstanding the lack of current interest in
screen studies in the avant-garde and its association with the ‘teleologies of negation’ (James Donald 1989), a reappraisal of the significance and relevance of Gidal’s contribution to the theorization and practice of cinema in higher education. I will contest the historical
reputation of Gidal and to some extent his own presentation of himself as an outsider (2006) with the argument that he simultaneously challenged and developed ideas central to screen studies to their most extreme and difficult conclusion. Gidal’s enduring influence on artists’
film in Britain has been acknowledged, but his contribution to screen theory is much less widely known, and the productive potential of his ideas not well understood or pursued.
The aesthetics and politics of obsolescence: Hand-made film in the era of the digital
Authors: Beugnet Martine , Knowles Kim
Published: May 2013

This article discusses contemporary handmade film-making as a form of critical practice that is now developing within the context of celluloid obsolescence and the frequent proclamations about the waning significance of film in the digital era. Because of its engagement with the materiality
of film, artisanal film-making offers itself as a form of metacinematic reflection – film reflecting on the possibility and meaning of its own disappearance and the eventuality of its survival. Hence, in the films described below, to work with celluloid is to go beyond ‘analogue
nostalgia’ in a restrictive, fetishistic sense, and to focus instead on the significance and topicality of the specific creative process that artisanal film-making entails. We argue that, whilst these films continue a structural-materialist tradition of experimental cinema, they reframe
and renew materialist practice by engaging with wider themes of technological and cultural obsolescence.
Reviews
Authors: Clum John M. , Jubin Olaf , Szego C. K.
Published: May 2013

A SHIP WITHOUT A SAIL: THE LIFE OF LORENZ HART, GARY MARMORSTEIN (2012) New York: Simon and Shuster, 527 pp., ISBN: 978-1-4165-9425-3, h/bk, $19.80

SEX, DRUGS, ROCK & ROLL AND MUSICALS, SCOTT MILLER (2011) Lebanon and New Hampshire: University Press of New England, 281pp.,
ISBN: 978-155553-743-2, p/bk, £19.35

OPERA INDIGENE: RE/PRESENTING FIRST NATIONS AND INDIGENOUS CULTURES, PAMELA KARANTONIS AND DYLAN ROBINSON (EDS) (2011) Farnham, UK and Burlington, VT: Ashgate. 357pp., ISBN: 978-0-754-66989-0, h/bk, $119.95, ISBN: 978-1-409-42406-2, e/bk
Pins and Needles (1937): Everything in moderation
Authors: Wright Trudi
Published: May 2013

Pins and Needles, a revue produced and performed by the International Ladies’ Garment Workers’ Union (ILGWU) in 1937, is frequently compared with another leftist revue of the Great Depression, Parade, produced by the Theater Guild in 1935. Parade presented satirical sketches
entirely from the liberal perspective, which apparently did not satisfy audiences, because the show closed in only five weeks. Pins and Needles, on the other hand, ran for three years, although it, too, was born out of a socially progressive culture. Why, then, did it succeed? The following
study will illuminate Pins and Needles’ balanced content, which was achieved by introducing skits that featured the tempered political viewpoints and socially progressive ideals of the union from which it came. Through the careful construction of content, and the decisions made by the
show’s creative team, which included theatre professionals and union leadership who answered to the cast of ILGWU members, Pins and Needles’ enjoyed wide-ranging and long-lasting appeal.
Post-Processing Continuous Shear Wave Signals Taken During Cone Penetrometer Testing
Authors: Ku Taeseo , Weemees Ilmar , Cargill Ethan , Mayne Paul W. , Woeller David
Published: May 2013

Continuous seismic velocity measurements use a special automated wave source and advanced post-processing analyses to provide fast, detailed, and reliable profiles of shear wave velocity (Vs) with depth. Conventional geophysical techniques such as crosshole tests (CHTs) and downhole tests (DHTs) in boreholes are slow because they have several required steps: (1) rotary drilling, (2) installation of casing and grouting, (3) inclinometer measurements (for CHTs), and (4) deployment of geophones for seismic readings. Direct-push technologies include the use of seismic cones and seismic dilatometers that offer DHT-type Vs data at intervals of 1 m or less without the need for drilling, casing, grouting, or separate field events. The recent development of a new portable autoseis source allows the generation of reliable and consistent shear waves either intermittently or as frequently as every 1 to 10 s. Continuous shear wave measurements can provide improved detailing of the small-strain stiffness (G0) at frequent depth intervals and fast field production times. Appreciable sensitivity errors in Vs calculations can be experienced because of the extremely small time shifts between adjacent shear wave records, as well as significant signal noise due to vibration, external sources, and refracted waves. This paper details continuous-interval seismic piezocone testing and explains how to handle signal post-processing in both the time domain and the spectral frequency domain in order to obtain a reliable in situ Vs profile.
Instrumented Dynamic Cone Penetrometer Corrected with Transferred Energy into a Cone Tip: A Laboratory Study
Authors: Byun Yong-Hoon , Lee Jong-Sub
Published: May 2013

For the site investigation of stiff soils, dynamic penetration testing, such as standard penetration testing (SPT) and dynamic cone penetration testing (DCP), has been performed. The dynamic cone tip responses, however, have not yet been evaluated. The objective of this study is the development and application of an instrumented dynamic cone penetrometer (IDCP) to evaluate the dynamic cone tip responses by considering the energy transferred into the cone tip. As the preliminary study on the development of the IDCP, the energy losses caused by the rod connection are experimentally estimated and numerically analyzed by considering the transmission and reflection coefficients. Strain gauges and accelerometers are installed in the cone tip and rod head of the IDCP to detect dynamic responses during penetration. Design concerns include the shape of the IDCP, the installation of strain gauges and accelerometers, and the mechanical resistance calibration. The developed IDCP was driven into compacted weathered soils in the chamber to measure the dynamic responses at the rod head and cone tip. From the measured responses, the energy transferred into the rod head and the cone tip was calculated. The experimental and numerical energy loss studies show that the energy loss increases with an increase in the number of rod connections. The penetration-test results show that the energy transferred into the cone tip is significantly smaller than that transferred into the rod head. Furthermore, the energy corrected dynamic responses at the cone tip clearly detected soil layers. This study suggests that energy losses caused by rod connections should be considered and that the IDCP may be a useful tool for the characterization of stiff soils.
A Clinical Case of Electronic Health Record Drug Alert Fatigue: Consequences for Patient Outcome
Authors: Carspecken C. William , Sharek Paul J. , Longhurst Christopher , Pageler Natalie M.
Published: May 2013

Despite advances in electronic medication order entry systems, it has been well established that clinicians override many drug allergy alerts generated by the electronic health record. The direct clinical consequences of overalerting clinicians in a pediatric setting have not been well demonstrated in the literature. We observed a patient in the PICU who experienced complications as a result of an extended series of non–evidence-based alerts in the electronic health record. Subsequently, evidence-based allergy alerting changes were made to the hospital’s system. Incorporating clinical evidence in electronic drug allergy alerting systems remains challenging, especially in pediatric settings.
Rinoliquorréia e hidrocefalia por gliose do aqueduto cerebral
Authors: Pereira Walter C. , Lima Neto A. Xavier de , Tenuto Rolando A.
Published: May 2013

É relatado um caso de hidrocefalia tardia, determinada por gliose do aqueduto cerebral, complicada com rinoliquorréia. A fístula do líquido cefalorraqueano se estabeleceu em conseqüência da erosão da sela turca pelo assoalho do 3.° ventriculo hipertenso e dilatado, determinando comunicação entre a cavidade ventricular e o seio esfenoidal. O paciente foi operado, tendo a fístula sido ocluída satisfatoriamente; previamente foi feita derivação ventrículo-peritoneal para evitar recidiva da hipertensão do sistema ventricular.
Sudorese em pacientes com moléstia de chagas crônica
Authors: Jardim Edymar
Published: May 2013

Foi estudada a sudoração em pacientes com moléstia de Chagas crônica, mediante estímulo térmico (teste de Minor). As perdas hídricas dos pacientes chagásicos foram significativamente menores do que as dos pacientes não chagásicos.
The electroencephalogram during spontaneous night sleep in epileptic patients
Authors: Ribeiro Rubens Moura , Lison Michel P. , Armbrust-Figueiredo J.
Published: May 2013

The sleep sistem results of the activity of two components: a descending component originated in the limbic structures, and an ascending system involving the bulbopontine structures which receives projections from the spinal cord components. Although the neocortex is not necessary for sleep mechanisms, it plays a very important role in sleep. Therefore, during the sleep state there is no significant quantitative difference in brain activity, but qualitative changes are recorded in EEG of epileptics patients during all night sleep.
Hemiplegias velo-faringo-laríngicas
Authors: Letti Nicanor , Lang Rudolf , Giordani Tito Livio
Published: May 2013

São relatados três casos de hemiplegias velo-faringo-laríngicas por lesão do núcleo ambíguo. A localização da lesão, os aspectos da paralisia velar e seu diagnóstico pela radiografia durante a fonação de consoantes orais e nasais são discutidos.
Indicadores econômicos da produção de flores tropicais no estado do Rio de Janeiro
Authors: Machado Neto Andrezza da Silva , Jasmim Janie Mendes , Ponciano Niraldo José
Published: May 2013

Esta pesquisa teve como objetivo determinar, mediante o cálculo do valor presente líquido (VPL), da taxa interna de retorno (TIR) e do Payback Econômico (PBE), a viabilidade econômica da produção de Alpinia purpurata, Etlingera elatior e Anthurium andraeanum, no Estado do Rio de Janeiro, bem como identificar e verificar, por meio da análise de sensibilidade, a influência de alguns fatores do sistema produtivo sobre a rentabilidade da atividade nas principais regiões produtoras. Os resultados mostram que a produção das espécies tropicais consideradas é uma atividade lucrativa e promissora para os agricultores no Estado do Rio de Janeiro. Porém, trata-se de um mercado em construção, cujos itens de maior impacto sobre a rentabilidade e o tempo de retorno do investimento (PBE) são o preço de venda do produto e o percentual de perdas da produção. Assim, a agregação de valor e o planejamento estratégico da produção são importantes medidas mercadológicas para a consolidação deste setor.
Comparação das técnicas de ELISA indireto e Imunofluorescência indireta na detecção de anticorpos anti-Neospora caninum em búfalas (Bubalus bubalis)
Authors: Silva Sandro P. , Mota Rinaldo A. , Faria Eduardo B. , Casseb Alexandre R. , Casseb Livia M.N. , Dias Hilma L.T.
Published: May 2013

Para comparar dois testes sorológicos na detecção de anticorpos anti-Neospora caninum em soros sanguíneos de búfalas, foram coletados amostras de 288 búfalas entre dois a dez anos de idade. Para identificar a presença de imunoglobulina G anti-N. caninum utilizou-se à reação de imunofluorescência indireta (RIFI), tendo o título 200 como ponto de corte, e o Ensaio Imunoenzimático indireto (ELISA-indireto), considerando-se positiva as amostras que obtiveram razão S/P>0,5. Observaram-se 153 (53,12%) animais soropositivos para N. caninum, através da RIFI, enquanto que 50 (17,36%) animais foram reagentes no ELISA. A ocorrência de anticorpos anti-N. caninum demonstram que o parasito esta circulando entre búfalas criadas no estado do Pará, sendo que ambos os teste de RIFI e ELISA podem ser utilizados para diagnosticar imunoglobulinas contra este agente. No entanto observou-se uma fraca correlação (Kappa=0,36) entre ambos os testes, considerando a RIFI como padrão ouro.
Aspectos clínicos e laboratoriais em ovinos submetidos a dietas com níveis elevados de enxofre com objetivo de indução de polioencefalomalácia
Authors: Delfiol Diego J.Z. , Cagnini Didier Q. , Cunha Paulo H.J. , Crosignani Nadia , Wouters Angélica T.B. , Wouters Flademir , Driemeier David , Borges Alexandre S.
Published: May 2013

A polioencefalomalacia (PEM) é uma doença neurológica que acomete ruminantes e pode ser desencadeada por diversos fatores, dentre eles o consumo excessivo de enxofre. Este trabalho teve como objetivo verificar a relação entre dietas ricas em enxofre, altos níveis de gás sulfídrico ruminal e a ocorrência de polioencefalomalácia em ovinos. Foram utilizados 18 ovinos, divididos em três grupos (G1, G2 e G3) que receberam diferentes níveis de enxofre na dieta; 0,2%, 0,9% e 1,2%, respectivamente. Exames físicos (frequência cardíaca, frequência respiratória, temperatura retal e motricidade ruminal) e complementares (concentração de sulfeto de hidrogênio ruminal, hemogasometria venosa, pH do fluído ruminal, concentração de cobre sérico e hepático, tomografia computadorizada, necropsia e histopatologia) foram realizados. A temperatura retal, a hemogasometria venosa e o pH do fluido ruminal permaneceram dentro dos valores de referência para a espécie. A motricidade ruminal estava diminuída nos grupos G2 e G3 em comparação com o G1 (controle). Quanto maior a ingestão de enxofre, menores foram os níveis de cobre sérico e hepático. Valores elevados de sulfeto de hidrogênio ruminal foram detectados nos grupos G2 e G3. Nenhum animal apresentou sinais clínicos de PEM. Nos exames de tomografia computadorizada, necropsia e exame histopatológico do sistema nervoso central (SNC), não foram observadas alterações compatíveis com PEM. É provável que algum outro fator esteja associado ao excesso de enxofre na dieta para o desenvolvimento de PEM em ovinos.
Lentivírus em caprinos leiteiros do semiárido paraibano: prevalência de anticorpos, fatores de risco e detecção molecular
Authors: Silva Maria L.C.R. , Castro Roberto S. , Maia Rita C. , Nascimento Sergio A. , Gomes Ana Lisa V. , Azevedo Sérgio S.
Published: May 2013

Os objetivos do presente trabalho foram determinar a prevalência de caprinos leiteiros soropositivos para a infecção por Lentivirus de pequenos ruminantes no semiárido do Estado da Paraíba, Nordeste do Brasil, identificar fatores de risco associados à prevalência de rebanhos positivos, e realizar a detecção molecular do agente. Foram utilizadas 1047 cabras leiteiras de 110 propriedades selecionadas aleatoriamente no Município de Monteiro, Estado da Paraíba, no período de março de 2009 a dezembro de 2011. Para o diagnóstico da infecção por Lentivirus, foi utilizado o teste de imunodifusão em gel de ágar (AGID). Um ano após foi realizada nova sorologia, e PCR em tempo real foi aplicada em amostras de sangue e leite de 48 cabras procedentes de quatro propriedades com animais soropositivos. As prevalências de propriedades positivas e de animais soropositivos na AGID foram 44,6% (IC 95% = 35,1% - 54,3%) e 8,1% (IC 95% = 5,6% - 16,8%), respectivamente. Realizar corte e desinfecção de umbigo (odds ratio = 2,44; p = 0,048) e condições de aglomeração de animais (odds ratio = 3,45; p = 0,048) foram associadas com a prevalência de propriedades positivas. Um ano após a realização do inquérito sorológico, foi verificada a permanência de animais infectados, detectados por PCR em tempo real a partir de amostras de sangue e leite. A PCR em tempo real das amostras de leucócitos circulantes apresentou boa performance, com sensibilidade de 100%, especificidade de 92,86%, concordância de 93,75% e indicador Kappa de 0,765. Sugere-se que seja realizado um trabalho de educação sanitária junto aos produtores sobre medidas de prevenção com o objetivo de reduzir a disseminação da infecção nos rebanhos.
Osteoporose em caprinos
Authors: Rosa Fábio B. , Galiza Glauco J.N. , Lucena Ricardo B. , Silva Taiara M. , Caprioli Rafaela A. , Barros Claudio S.L. , Fighera Rafael A. , Kommers Glaucia D.
Published: May 2013

Foi realizado um estudo de casos de osteoporose em caprinos provenientes de uma propriedade na área de abrangência do LPV-UFSM, determinando a epidemiologia, o quadro clínico-patológico e discutindo os prováveis mecanismos patogenéticos. Cinco cabras, fêmeas, SRD, de seis meses a seis anos de idade foram afetadas. As cabras eram mantidas em campo nativo, sem suplementação com ração e sob superlotação. Os principais sinais clínicos foram emagrecimento, dificuldade de locomoção e permanência em decúbito por longos períodos. As principais alterações macroscópicas nos ossos examinados foram vistas nas superfícies de corte e caracterizavam-se por depleção do osso esponjoso (porosidade) e redução acentuada da espessura do osso cortical. Havia também marcada atrofia serosa da gordura da medula óssea. Microscopicamente, nas regiões avaliadas (úmero proximal, rádio distal, fêmur distal, tíbia proximal e corpos das vértebras lombares) foi observada redução moderada a acentuada do número e da espessura das trabéculas ósseas nas epífises e metáfises dos ossos longos e nos corpos vertebrais. Os achados clínico-patológicos indicaram que a osteoporose observada provavelmente foi causada pela desnutrição. As alterações ósseas (diminuição no número e na espessura das trabéculas do osso esponjoso) sugerem que ambos os mecanismos, má formação óssea e reabsorção óssea aumentada, contribuíram para a ocorrência de osteoporose nos caprinos deste estudo.
Outbreak of autochthonous canine visceral leishmaniasis in Santa Catarina, Brazil
Authors: Steindel Mário , Menin Álvaro , Evangelista Tatiane , Stoco Patrícia H. , Marlow Mariel A. , Fleith Renata C. , Pilati Celso , Grisard Edmundo C.
Published: May 2013

The present study reports the first outbreak of autochthonous canine visceral leishmaniasis in Florianópolis, Santa Catarina, southern Brazil. Following the report of two cases of CVL, the Control Center of Zoonotic Diseases conducted a serological survey by ELISA and IFAT assays in seven districts of the Santa Catarina Island. Eleven seropositive dogs of autochthonous transmission were used in the present study. Infection by Leishmania sp. was confirmed by parasitological examination of bone marrow, liver, spleen and lymph nodes, culture in Schneider's medium and PCR. Leishmania sp. isolates were characterized by PCR-RFLP and hybridization with specific probes, allowing for the identification of Leishmania infantum. Autochthonous transmission of this disease in an area with high tourist traffic presents a major public health concern and signifies the emergence of an important zoonosis in southern Brazil. Therefore, the implementation of surveillance and control measures is imperative to prevent the spread of the disease among the canine population as well as transmission to the human population.
Some virulence genes of Escherichia coli isolated from cloacal swabs of healthy Alagoas Curassows (Pauxi mitu) in Brazil
Authors: Saidenberg André A.B. , Allegretti Luciana , Astolfi-Ferreira Claudete C.S. , Ferreira Antônio J.P. , Almeida Marcelo A. , Raso Tânia F.
Published: May 2013

Birds of the Cracidae family (curassows, guans, and chachalacas) are endemic of the Neotropics and 50 species are currently classified. Brazil has 22 species, seven of which are considered threatened. The Alagoas Curassow (Pauxi mitu) species is considered extinct in the wild; but about 120 birds are alive in captivity. Conservation of this species depends entirely on correct management. Health reports of both wildlife and captive curassows are rare. In this study the presence of Escherichia coli was evaluated in 23 healthy Alagoas Curassows from two private breeding centres. E. coli was isolated from cloacal swabs, and the presence of genes encoding cytotoxic necrotising factor 1 (cnf1), alpha-haemolysin (hly), aerobactin (iuc), serum resistance (iss) and the following adhesions: S fimbriae (sfa), pili associated with pyelonephritis (pap) and temperature-sensitive haemagglutinin (tsh) were investigated. E. coli was isolated from 78.3% (18/23) of the birds, and the percentage of curassows colonized by E. coli was similar between the two facilities. From the 22 E. coli isolates, 15 (68.2%) were positive for at least one virulence factor by PCR, and the most frequently found gene was iss (50%). No curassows had clinical signs of disease. Nevertheless, the presence of some E. coli strains may be a concern to the wildlife in captivity. Additional health surveillance studies are essential to guarantee successful conservation programmes for threatened cracids in Brazil.
Teste de ELISA indireto para diagnóstico sorológico de leishmaniose visceral em canídeos silvestres
Authors: Ferreira Paulo R.B. , Larangeira Daniela F. , Oliveira Lídia S. de , Malta Marcelo de C.C. , Gomes Marta C. , Bastos Bruno L. , Portela Ricardo W. , Barrouin-Melo Stella Maria
Published: May 2013

Na América do Sul, alguns canídeos silvestres são considerados reservatórios naturais da Leishmania chagasi. A resposta imunológica desses animais à Leishmania é pouco conhecida, havendo a necessidade de métodos diagnósticos adequados para esse fim. No presente estudo, é descrita a padronização do ensaio imunoenzimático indireto (ELISA) para o diagnóstico sorológico de leishmaniose visceral em canídeos silvestres brasileiros. Foram estudadas amostras de soro e plasma de 12 canídeos cativos: sete lobos-guará (Chrysocyon brachyurus), três raposinhas (Lycalopex vetulus) e dois cachorros-do-mato (Cerdocyon thous). As amostras de um C. brachyurus e uma L. vetulus, cativos em área endêmica para LV, que apresentavam doença clínica e positividade em testes de Imunofluorescência Indireta e Reação em Cadeia de Polimerase, foram utilizadas como controles positivos. Foram comparados os conjugados anti-IgG de cão e proteína A, ambos ligados a peroxidase, cujos testes detectaram quatro (04/12) e três (03/12) C. brachyurus soropositivos para anticorpos anti-Leishmania sp., respectivamente. As médias das densidades ópticas (DOs) das amostras negativas foram nitidamente mais baixas do que as médias das DOs dos positivos tanto no ELISA com anti-IgG de cão (4,8 vezes) como com proteína A (15,5 vezes). Os soros de três C. brachyurus positivos no ELISA indireto foram avaliados por Western blotting e identificaram 22 bandas, sendo imunodominantes as de peso molecular de 19, 22, 24, 45 e 66 kDa. Os testes ELISA com a proteína A e o conjugado anti-IgG de cão apresentaram respectivamente concordância excelente (Kappa = 1; p<0,001) e moderada (Kappa = 0,8; p<0,0015), com o Western blotting. Ambos foram, portanto, considerados adequados a avaliações de triagem de animais cuja resposta humoral de anticorpos indica contato com o parasito, úteis para subsidiar estudos para adequação de metodologias específicas para os canídeos silvestres.