bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-term clinical results of the Metasul metal-on-metal total hip arthroplasty: 12.6 years follow-up of 128 primary total hip replacements
Authors: Zuiderbaan Hendrik A. , Visser Dennis , Sierevelt Inger N. , Penders Janine , Verhart Jeanette , Vergroesen Diederik A.
Published: October 2017

Introduction:

The purpose of the present study is to report the long-term clinical results of an uncemented total hip arthroplasty (THA) using a Metasul metal-on-metal (MoM) 28-mm bearing and to evaluate the long-term serum cobalt levels.

Methods:

At an average of 12.6 years following primary THA, we retrospectively reviewed the clinical results of the first 116 consecutive patients (128 THAs) in our institution who underwent 28-mm Metasul MoM THA. Of the 78 patients who were able to visit our outpatient clinic, serum cobalt levels were evaluated.

Results:

The overall survival rate of the cohort was 96.1% (95% confidence interval [CI], 93.2-99.6), 12.6 years (95% CI, 12.3-12.7 years) following surgery. 3 patients had undergone revision due to aseptic loosening of the stem and 2 patients sustained a periprosthetic fracture. The average modified Harris Hip Score was 90 (72-97) and the average Oxford Hip Score was 56 (48-60), representing both excellent outcome scores. The average serum cobalt of the entire cohort was 20.1 nmol/L (range 8.5-227.7 nmol/L). Serum cobalt levels of patients with a bilateral MoM THA were significantly higher (35.0 nmol/l, p<0.01). No relation between serum cobalt levels, subjective outcome, radiolucent lines on radiographs and survivorship of the implant was noted.

Conclusions:

Long-term results of the metasul MoM bearing articulation in THA seem to be excellent, although cobalt serum levels should be monitored closely.
A pilot study on the efficacy and safety of a minimally invasive surgical and anesthetic approach for ventricular assist device implantation
Authors: Bejko Jonida , Pittarello Demetrio , Falasco Gianclaudio , Di Gregorio Guido , Tarzia Vincenzo , Rizzoli Giulio , Gregori Dario , Gerosa Gino , Bottio Tomaso
Published: October 2017

Background:

The aim of our study was to compare 2 surgical and anesthetic approaches during ventricular assist device implantation.

Methods:

68 patients (50.4 ± 17.1 years old) were supported with the HeartWare® HVAD (32 patients) and the Jarvik 2000 VAD (36 patients) between January 2010 and August 2016. Two surgical techniques were applied: a minimally invasive approach with the aid of paravertebral-block (mini-invasive group, 41 patients) and a standard-surgical-approach with the aid of general anesthesia (27 patients).

Results:

The minimally invasive approach allowed faster postoperative recovery by significantly reducing the duration of surgery (p<0.05), anesthesia (p<0.05), mechanical ventilation (p<0.05), inotropic support (p<0.05), ICU and in-hospital stay (p<0.05), and time to first mobilization (p<0.05). No case of epidural hematoma was observed. Eleven patients died (16%) at 30 days, 3 in the mini-invasive group (7.3%) and 8 in the invasive group (29.6%).

Conclusions:

Minimally invasive approaches play a substantial role in VAD surgery by facilitating faster recovery, which is important for patients at very high risk.
Assessment of monomer release from 3 different fissure sealants
Authors: Görkem Ulu Güzel K. , Sönmez Işıl
Published: October 2017

Background:

Light-activated resin-based dental fissure sealants are the most widely accepted among clinicians. The objective of this study was to determine monomer release of 3 different light-curing fissure sealants in vitro: Control Seal (Voco, Germany), Fissurit FX (Voco, Germany) and R&D Series Fıssured Nova (Imicrly, Turkey).

Methods:

Each material was polymerized with a curing light: Valo Cordless (Ultradent) LED in standard mode for 20 seconds (n = 27) and 40 seconds (n = 27) and in Xtra power mode (plasma arc) for 3 seconds (n = 27). High-performance liquid chromatography (HPLC) was used to measure the amount of monomers released over 1, 3 and 7 days.

Results:

Plasma arc groups showed the highest release of monomers at 1, 3 and 7 days in the 3 fissure sealant groups (p<0.001). The greatest release of bisphenol A glycidyl methacrylate (bis-GMA) determined for R&D Series Fissured Nova both with LED 20 seconds and LED 40 seconds and for Control Seal was with the plasma arc. With time, release of the monomer was reduced for all polymerization systems.

Conclusions:

Efficiency of the polymerization system and applying the recommended curing time for light-activated resin-based dental materials are very important to protect the patient from potential hazards of residual monomers.
Comportamento à flexão de vigas de aço tubulares retangulares submetidas a forças transversais localizadas
Authors: Flor Jacqueline Maria , Fakury Ricardo Hallal , Caldas Rodrigo Barreto , Aguiar Davi Pedrosa de
Published: October 2017

Este artigo apresenta uma investigação preliminar sobre a influência de forças transversais localizadas no valor do momento resistente de vigas de aço tubulares retangulares com seção transversal compacta. Dois protótipos de vigas de 6 m de comprimento foram submetidos a ensaio de flexão sob a ação de duas forças transversais localizadas equidistantes dos apoios. Um modelo numérico foi desenvolvido para simular o comportamento das vigas e empregado em um estudo paramétrico. Os parâmetros investigados foram o método de aplicação das forças e o raio de concordância entre as mesas e as almas do tubo retangular. Constatou-se que seções transversais tubulares retangulares compactas podem apresentar falha oriunda de grandes deformações plásticas localizadas na região imediatamente abaixo da área de aplicação da força localizada, quando essa força comprime as almas. A colocação de chapas de reforço nas almas reduz significativamente o efeito deletério no momento resistente. Adicionalmente, observou-se que o efeito é mais acentuado nas seções transversais tubulares retangulares com raios de concordância mais elevados.
Renal cell carcinoma metastasis to the vocal cord: A case report
Authors: Nielsen Signe B. , Swan Christer Z.
Published: October 2017

Background: Approximately 15% of renal cell carcinoma (RCC) cases develop extracranial head and neck metastases. Metastatic lesions to the larynx from outside the head and neck region are rare.Methods: We report an unusual case of RCC metastatic to the left vocal cord, in a 57-year-old female. The patient suffered from metastatic RCC, detected 11 months prior to onset of hoarseness, which was her only symptom of glottic metastasis. The tumor was radically excised applying direct laryngoscopy.Results: Histopathologic examination revealed metastasis of RCC clear cell type.Conclusions: Glottic metastases do occur in patients with metastatic RCC and laryngeal symptoms, such as persistent hoarseness, should prompt otolaryngological examination.
Using Simple Alternative Hypothesis to Increase Statistical Power in Sparse Categorical Data
Authors: Mutter Louis , B. Kim Steven
Published: October 2017

There are numerous statistical hypothesis tests for categorical data including Pearson's Chi-Square goodness-of-fit test and other discrete versions of goodness-of-fit tests. For these hypothesis tests, the null hypothesis is simple, and the alternative hypothesis is composite which negates the simple null hypothesis. For power calculation, a researcher specifies a significance level, a sample size, a simple null hypothesis, and a simple alternative hypothesis. In practice, there are cases when an experienced researcher has deep and broad scientific knowledge, but the researcher may suffer from a lack of statistical power due to a small sample size being available. In such a case, we may formulate hypothesis testing based on a simple alternative hypothesis instead of the composite alternative hypothesis. In this article, we investigate how much statistical power can be gained via a correctly specified simple alternative hypothesis and how much statistical power can be lost under a misspecified alternative hypothesis, particularly when an available sample size is small.
Conducting achievements of Witold Rowicki in Poland and abroad
Authors: Juszyńska Krystyna
Published: October 2017

Witold Rowicki (1914–1989) was one of the most renowned Polish conductors of the 2nd half of the 20th century who gave unique renditions of symphonic music, based on a careful selection of dynamics, tempo and sound proportions between particular groups of instruments. The range of his artistic achievements as a conductor is impressive and comprises over 600 concerts in Poland (most of them with the Warsaw Philharmonic and the Polish National Radio Symphony Orchestra in Katowice), more than 500 concerts abroad, huge concert repertoire ranging from classicism to contemporary music, performances given alongside a number of outstanding soloists, more than 100 records, compositional output, numerous arrangements and instrumentations, popularization of music, teaching activity. His biggest organizational achievement was the revival of the Polish National Radio Symphony Orchestra in Katowice (1945) and the Warsaw Philharmonic Symphony Orchestra (1951) after the World War II. Witold Rowicki was a conductor of a particular merit for Polish culture.
Professor Jan Szyrocki – the pioneer of the West Pomeranian choral art
Authors: Halec Barbara
Published: October 2017

The article presents the figure of Jan Szyrocki, a conductor, pedagogue and music culture promoter, connected with Szczecin for most of his life. He was the founder of the “Słowiki” Boys’ Choir, the “Berżeretki” Girls’ Choir and, first and foremost, the Choir of the University of Technology in Szczecin, which he cooperated with continually for 50 years. The article also describes Jan Szyrocki’s contribution to the establishment of the International Choral Festival in Międzyzdroje and “In terra pax” Choral Academy, as well as his collaboration with renowned composers (e.g. Andrzej Koszewski, Krzysztof Penderecki, Jan Hawel, Marek Jasiński) and the conductor of the Szczecin Philharmonic – Stefan Marczyk. The article also discusses other issues, such as the didactic, social and cultural activity of Prof. Jan Szyrocki, his professional activity in the Szczecin branch of the Academy of Music in Poznań and in the College of Music Culture, founded on his initiative at the University of Technology in Szczecin, as well as information on his membership in cultural organizations and juries, awarded prizes, medals and distinctions.
The oral cavity – potential source of stem cells
Authors: Brożek Rafał , Kurpisz Maciej , Koczorowski Ryszard
Published: October 2017

The purpose of this review is to present the current knowledge regarding the hierarchy of stem cells originating from the oral cavity, which could have a potential value when applied to regenerative stomatology. It must be particularly emphasized that the heterogenous nature of its biology and function within oral compartment may predispose them to different types of applications. Stem cells can be perceived as immature, primitive and unspecialized types of cells with the ability to proliferate, self-renew and differentiate into specialized progeny according to the compartmental signaling. Their presence in tissue reservoirs was already discovered in many organs and tissues as well as in the stomatognathic system. The oral cavity appears to be an exceptionally attractive site to acquire stem cells. The common presence and easy access to these cells in dental and peridental tissues provides a real chance to apply them for therapeutic purposes. Such an opportunity would also be neutral to bioethical and moral issues, assuming autologous stem cells employment. Many authors suspect that stem
cells have epigenetic memory, so some of their features can be inherited through generations.
They are not connected, however, with DNA sequence modifications. It is, therefore, justified
to apply the cells, which have the oral cavity as their natural reservoir, in interventions associated
with tissue engineering within the stomatognathic system. An increasing number of
clinical trials, among which the number of randomized studies with large group of patients is
progressively carried out, allows for a prediction that shortly therapeutic methods based on
stem cells of dental origin may be implemented to the routine repertoire of clinical practice.
The mRNA expression levels of uncoupling proteins 1 and 2 in mononuclear cells from patients with metabolic disorders: obesity and type 2 diabetes mellitus
Authors: Margaryan Sona , Witkowicz Agata , Partyka Anna , Yepiskoposyan Levon , Manukyan Gayane , Karabon Lidia
Published: October 2017

Introduction: Type 2 diabetes mellitus (T2DM) and obesity are metabolic disorders whose major hallmark is insulin resistance. Impaired mitochondrial activity, such as reduced ratio of energy production to respiration, has been implicated in the development of insulin resistance. Uncoupling proteins (UCPs) are proton carriers, expressed in the mitochondrial inner membrane, that uncouple oxygen consumption by the respiratory chain from ATP synthesis.
Aim: The aim of the study was to determine transcriptional levels of UCP1 and UCP2 in peripheral blood mononuclear cells (PBMCs) from patients with metabolic disorders: T2DM, obesity and from healthy individuals.
Material/Methods: The mRNA levels of UCP1, UCP2 were determined by Real-Time PCR method using Applied Biosystems assays.
Results: The UCP1 mRNA expression level was not detectable in the majority of studied samples, while very low expression was found in PBMCs from 3 obese persons. UCP2 mRNA expression level was detectable in all samples. The median mRNA expression of UCP2 was lower in all patients with metabolic disorders as compared to the controls (0.20+0.14 vs. 0.010+0.009, p=0.05). When compared separately, the differences of medians UCP2 mRNA expression level between the obese individuals and the controls as well as between the T2DM patients and the controls did not reach statistical significance.
Conclusions: Decreased UCP2 gene expression in mononuclear cells from obese and diabetic patients might
contribute to the immunological abnormalities in these metabolic disorders and suggests its
role as a candidate gene in future studies of obesity and diabetes.
Evaluation of mericon E. coli O157 Screen Plus and mericon E. coli STEC O-Type Pathogen Detection Assays in Select Foods: Collaborative Study, First Action 2017.05
Authors: Bird Patrick , Benzinger M Joseph , Bastin Benjamin , Crowley Erin , Agin James , Goins David , Armstrong Marcia ,   Collaborators:, Arnts L , Clark D , Draper E , Duss A , Endres M , Franklin J , Guden K , Hariram U , Kaur N , Kim A , Klass N , Kupski B , Le S , Liska C , Mastalerz A , Matheus K , Sexton A , Thompson L , Wright H , Zheng J
Published: October 2017

QIAGEN mericon Escherichia coli O157 Screen Plus and mericon E. coli Shiga toxin-producing E. coli (STEC) O-Type Pathogen Detection Assays use Real-Time PCR technology for the rapid, accurate detection of E. coli O157 and the “big six” (O26, O45, O103, O111, O121, O145) (non-O157 STEC) in select food types. Using a paired study design, the assays were compared with the U.S. Department of Agriculture, Food Safety Inspection Service Microbiology Laboratory Guidebook Chapter 5.09 reference method for the detection of E. coli O157:H7 in raw ground beef. Both mericon assays were evaluated using the manual and an automated DNA extraction method. Thirteen technicians from five laboratories located within the continental United States participated in the collaborative study. Three levels of contamination were evaluated. Statistical analysis was conducted according to the probability of detection (POD) statistical model. Results obtained for the low-inoculum level test portions produced a difference between laboratories POD (dLPOD) value with a 95% confidence interval of 0.00 (–0.12, 0.12) for the mericon E. coli O157 Screen Plus with manual and automated extraction and mericon E. coli STEC O-Type with manual extraction and –0.01 (–0.13, 0.10) for the mericon E. coli STEC O-Type with automated extraction. The dLPOD results indicate equivalence between the candidate methods and the reference method.
Generalizing-Promoting Actions: How Classroom Collaborations Can Support Students' Mathematical Generalizations
Authors: Ellis Amy B.
Published: October 2017

Generalization is a critical component of mathematical activity and has garnered increased attention in school mathematics at all levels. This study documents the multiple interrelated processes that support productive generalizing in classroom settings. By studying the situated actions of 6 middle school students and their teacher–researcher working on a 3–week unit on quadratic growth functions that can be represented by y = ax2, the study identified 7 major categories of generalizingpromoting actions. These actions represent how teachers and students can act in interaction with other agents to foster students' generalizing activities. Two classroom episodes are presented that identify cyclical interaction processes that promoted the development and refinement of generalizations. The results highlight generalization as a dynamic, socially situated process that can evolve through collaborative acts.
The Splitting Loope
Authors: Wilkins Jesse L. M. , Norton Anderson
Published: October 2017

Teaching experiments have generated several hypotheses concerning the construction of fraction schemes and operations and relationships among them. In particular, researchers have hypothesized that children's construction of splitting operations is crucial to their construction of more advanced fractions concepts (Steffe, 2002). The authors propose that splitting constitutes a psychological structure similar to that of a mathematical group (Piaget, 1970b): a structure that introduces mutual reversibility of students' partitioning and iterating operations that the authors refer to as the splitting loope. Data consisted of 66 sixth–grade students' written performance on 20 tasks designed to provoke responses that would indicate particular fractions schemes and operations. Findings are consistent with hypotheses from related teaching experiments. In particular, they demonstrate–consistent with the notion of the splitting loope—that equipartitioning and the partitive unit fraction scheme mediate the construction of splitting from partitioning and iterating operations.
Young Workers’ Perceptions of Trade Unions in Portugal
Authors: Kovács Ilona , Dias João , da Conceição Cerdeira Maria
Published: October 2017

This paper seeks to capture how unions are perceived by young workers in Portugal and to identify different types of perceptions. Our analysis considers both structural factors and subjective experiences and is based on semi-structured interviews with young people working in sectors with a high concentration of youth employment. The fact that young workers are increasingly exposed to the pressures of unemployment and precarious work might suggest that there is homogeneity in their perceptions about trade unions and collective action. However, our results show that young workers’ perceptions are not homogenous and that they interconnect with distinct segments, characterized by different socio-economic conditions, as defined by family status, education level and position in the labour market. Three types of perceptions were identified by content analysis of the interviews: positive, negative and critical perceptions. A final segment of younger and less-skilled workers, of families with low educational and economic resources and having left school prematurely, have neither information nor any understanding about unions.

Our findings support the thesis that diversity of educational and early labour market experiences, which characterize transition processes to adulthood, shape the relation between young workers and unions, in particular the motivation to join unions. Capturing the diversity of young workers experiences and perceptions is a challenge to industrial relations research, as well as to trade unionism. It can provide unions with important insights into how to adapt their strategies to recruit new young members and to mobilize the latent interests of young workers in collective action.
Du territoire de projets à l’anti-projet de territoire. Grand équipement sportif et construction de l’intercommunalité en agglomération intermédiaire
Authors: CHABOCHE José
Published: October 2017

Cet article s’inscrit dans la problématique des mutations contemporaines des politiques urbaines à travers, notamment, une tendance mondiale à leur conférer un caractère spectaculaire (Bélanger, 2000). Dans ce contexte, L’Odyssée, le plus imposant complexe aquatique-patinoire de France, financé par Chartres Métropole (« l’Agglo »), contribue-t-il efficacement à la construction intercommunale ? Observation directe, enquête archivistique et littérature scientifique charpentent cette recherche en géographie sociale. Outre la démonstration des effets contrastés de L’Odyssée sur la construction intercommunale, nos résultats montrent qu’il synthétise des évolutions plus globales par ses modes de conception, de réalisation et d’exploitation : omniprésence de l’intercommunalité dans le développement territorial, sans mandat démocratique direct ; concurrence interurbaine généralisée et multiscalaire ; accentuation de la marchandisation et de la rétraction de l’espace public urbain ; pilotage autoritaire de grandes opérations d’aménagement par des élites politiques attentives aux intérêts privés, lesquels sapent le maillage territorial d’équipements sportifs et réduisent les bénéfices collectifs au détriment des catégories sociales les moins bien positionnées. Stratégies individuelles et gouvernance conflictuelle liées à ce modèle amoindrissent les effets géographiques de l’intercommunalité et contribuent à l’essor de la figure de l’anti-projet de territoire.
“The place is a prison, and you can’t change it”
Authors: Durham Brook
Published: October 2017

Speedwell Military Hospital was a hospital for veterans of the Canadian Expeditionary Force located in the newly-built Ontario Reformatory in Guelph. Speedwell was part of a nation-wide program administered by the Department of Soldiers’ Civil Re-Establishment (DSCR) during the First World War intended to neutralize some of the social dangers associated with demobilization. As the health of individual veterans at Speedwell became closely associated with the nation’s economic strength, the ultimate goal of hospitals like Speedwell was the transformation of sick and wounded veterans into healthy and productive workers. However, as the needs of patients changed after the war, the initial promise of Speedwell as a site of rehabilitative labour made it clearly unsuitable for veterans in need of long-term convalescence care.
Religion as Self-Transcendence. A Simmelian Framework for Authenticity
Authors: Montemaggi Francesca Eva Sara
Published: October 2017

Georg Simmel’s writings on religion have too often been overlooked, notwithstanding his undisputed status as one of the founders of sociology. Simmel’s metaphysical inclination may give the impression that his thoughts on religion are closer to theology than sociology. This article proposes an interpretation of Simmel’s notion of religiosity (Die Religiosität) in conjunction with the notion of self-transcendence, part of the philosophy of life (Lebensphilosophie) he espoused towards the end of his life. The article does not pursue a filologically accurate position, but a development drawing on Simmel’s notions. Accordingly, it is proposed to interpret religiosity as a sensitivity to self-transcendence, the awareness of social conditioning, or “facticity”, and the striving towards going beyond it. The tension between facticity and self-transcendence reflects – what Simmel called – the ‘conflict of culture’, the ‘malaise’ of the fragmentation of the self resulting from the social differentiation of modern society. Religiosity, as a sensitivity to self-transcendence, is expressed in the pursuit of authenticity thus countering the conflict of culture. This interpretation allows us to see religion as a path, albeit not the only one, to authenticity, understood as challenging facticity, which echoes in later existentialist philosophy and contemporary empirical studies.
Posterior parietal cortex estimates the relationship between object and body location during locomotion
Authors: Marigold Daniel S , Drew Trevor
Published: October 2017

We test the hypothesis that the posterior parietal cortex (PPC) contributes to the control of visually guided locomotor gait modifications by constructing an estimation of object location relative to body state, and in particular the changing gap between them. To test this hypothesis, we recorded neuronal activity from areas 5b and 7 of the PPC of cats walking on a treadmill and stepping over a moving obstacle whose speed of advance was varied (slowed or accelerated with respect to the speed of the cat). We found distinct populations of neurons in the PPC, primarily in area 5b, that signaled distance- or time-to-contact with the obstacle, regardless of which limb was the first to step over the obstacle. We propose that these cells are involved in a sensorimotor transformation whereby information on the location of an obstacle with respect to the body is used to initiate the gait modification.
Cardiovascular adaptation to hypoxia and the role of peripheral resistance
Authors: Cowburn Andrew S , Macias David , Summers Charlotte , Chilvers Edwin R , Johnson Randall S
Published: October 2017

Systemic vascular pressure in vertebrates is regulated by a range of factors: one key element of control is peripheral resistance in tissue capillary beds. Many aspects of the relationship between central control of vascular flow and peripheral resistance are unclear. An important example of this is the relationship between hypoxic response in individual tissues, and the effect that response has on systemic cardiovascular adaptation to oxygen deprivation. We show here how hypoxic response via the HIF transcription factors in one large vascular bed, that underlying the skin, influences cardiovascular response to hypoxia in mice. We show that the response of the skin to hypoxia feeds back on a wide range of cardiovascular parameters, including heart rate, arterial pressures, and body temperature. These data represent the first demonstration of a dynamic role for oxygen sensing in a peripheral tissue directly modifying cardiovascular response to the challenge of hypoxia.
‘Lyin' Ted’, ‘Crooked Hillary’, and ‘Deceptive Donald’: Language of Lies in the 2016 US Presidential Debates
Authors: Bond Gary D. , Holman Rebecka D. , Eggert Jamie‐Ann L. , Speller Lassiter F. , Garcia Olivia N. , Mejia Sasha C. , Mcinnes Kohlby W. , Ceniceros Eleny C. , Rustige Rebecca
Published: October 2017

Language in the high‐stakes 2016 US presidential primary campaign was contentious, filled with name‐calling, personal attacks, and insults. Language in debates served at least three political functions: for image making, to imagine potential realities currently not in practice, and to disavow facts. In past research, the reality monitoring (RM) framework has discriminated accurately between truthful and deceptive accounts (~70% classification). Truthful accounts show greater sensory, time and space, and affective information, with little evidence of cognitive operations. An RM algorithm was used with Linguistic Inquiry and Word Count software to code candidates' language. RM scores were significantly higher in fact‐checked truth statements than in lies, and debate language in the 2016 primaries was as deceptive as fact‐checked lies. In a binary logistic regression model, one RM criterion, cognitive processes, predicted veracity using computerized RM, classifying 87% of fact‐checked truth statements but only 28% of fact‐checked lie statements (63% classification overall).Copyright © 2017 John Wiley & Sons, Ltd.
One‐Pot Synthesis of N‐Alkyl Benzotriazoles via a Brønsted Acid‐Catalyzed Three‐Component Reaction
Authors: Wang Xiangdong , Jia Chunqi , Feng Yadong , Wang Lianhui , Cui Xiuling
Published: October 2017

A novel three‐component condensation reaction of benzotriazoles, aldehydes and tertiary anilines efficiently catalyzed by readily available organic acid p‐toluenesulfonic acid (PTSA) has been developed. A series of N‐alkyl benzotriazoles were synthesized in up to 97% yield for 21 examples starting from anilines, benzotriazoles and formaldehyde. This strategy features a simple system, atom economy, environmental friendliness, high efficiency, excellent regioselectivity, good functional group tolerance, easily available starting materials, and cheap catalyst. The mechanistic studies indicated that aza quinone methide was probably involved as an intermediate in this transformation.

magnified image
Receding horizon optimal operation and control of a solar‐thermal district heating system
Authors: Xu Xiaodong , Yuan Yuan , Dubljevic Stevan
Published: October 2017

This work focuses on the receding horizon optimal control for a solar‐thermal district heating (STDH) system containing lumped parameter and distributed parameter subsystems. A common STDH system includes solar collector system, a short‐term energy storage tank and a district heating loop system with a secondary gas boiler system. The inclusion or exclusion of these components leads to different operational and working modes. Detailed system description and mathematical models are provided, and three working modes are introduced and in each mode several operations are demonstrated and addressed. Single‐objective and multiobjective problems are formulated. Moreover, in the mode where gas boiler system is included to help addressing the district heating demand, the internal model based boundary servo‐control approach is proposed and applied to obtain desired boiler water temperatures such that the expected district heating demand can be satisfied. Moreover, a boundary state observer is designed for the considered solar collector system. © 2017 American Institute of Chemical Engineers AIChE J, 64: 1217–1233, 2018
Simulation on hydrogen storage properties of metal‐organic frameworks Cu‐BTC at 77–298 K
Authors: Chen Shumin , Shi Yumei , Gu Bo
Published: October 2017

In recent years, many researchers have studied on the hydrogen storage properties of metal‐organic frameworks (MOFs) by grand canonical Monte Carlo (GCMC) simulation. At present, the GCMC studies of Cu‐BTC (BTC: benzene‐1,3,5‐tricarboxylate) which is a prototypical metal‐organic framework mainly adopt the classical force fields, the simulation temperatures are mainly focus on 298 and 77 K, and most researchers did not consider the effects of quantum effects at low temperature. Therefore, we used the quantum effects to correct the classical force fields and the force fields with more accurate simulation results were used to simulate the hydrogen adsorption performances of Cu‐BTC in the temperature range of 77–298 K and the pressure range of 1–8 MPa at each temperature. The results show that the effects of quantum effects on the hydrogen storage of Cu‐BTC cannot be neglected and the corrected Dreiding force field can simulate hydrogen adsorption performances of Cu‐BTC more accurately at low temperature. © 2017 American Institute of Chemical Engineers AIChE J, 64: 1383–1388, 2018
Multivariable model predictive control of a novel rapid pressure swing adsorption system
Authors: Urich Matthew D. , Vemula Rama Rao , Kothare Mayuresh V.
Published: October 2017

A multivariable model predictive control (MPC) algorithm is developed for the control and operation of a rapid pressure swing adsorption (RPSA)‐based medical oxygen concentrator. The novelty of the approach is the use of all four step durations in the RPSA cycle as independent manipulated variables in a truly multivariable context. The RPSA has a complex, cyclic, nonlinear multivariable operation that requires feedback control, and MPC provides a suitable framework for controlling such a multivariable system. The multivariable MPC presented here uses a quadratic optimization program with integral action and a linear model identified using subspace system identification techniques. The controller was designed and tested in simulation using a complex, highly coupled, nonlinear RPSA process model. The model was developed with the least restrictive assumptions compared to those reported in the literature, thereby providing a more realistic representation of the underlying physical phenomena. The resulting MPC effectively tracks set points, rejects realistic process disturbances and is shown to outperform conventional PID control. © 2017 American Institute of Chemical Engineers AIChE J, 64: 1234–1245, 2018
Measures for Sustainable Investment Decisions and Business Strategy – A Triple Bottom Line Approach
Authors: Cubas‐Díaz Maite , Martínez Sedano Miguel Ángel
Published: October 2017

Traditionally, most investors have only taken economic variables (profitability and risk) into account when making investment decisions. In this paper we propose two measures, the Relative Sustainable Performance Measure (RSPM) and the Measure of Commitment‐failure (MC), that permit sustainable decision making, which takes environmental and social variables into consideration in addition to the economic variables, for both investors and companies themselves. This makes a triple bottom line (TBL) approach to investment decision making possible. We apply our measures to the worldwide chemical sector and validate them. Moreover, we propose a 2D graphical sustainability analysis, which is simple and easy for investors to understand when making investment decisions and can be used if they are concerned about environmental and social matters. It also enables companies to analyse their sustainability performance and adapt their business plans accordingly. Copyright © 2017 John Wiley & Sons, Ltd and ERP Environment
Does the Eco‐Management and Audit Scheme Foster Innovation in European Firms?
Authors: Montobbio Fabio , Solito Ilaria
Published: October 2017

This paper studies whether environmental management systems can spur eco‐innovation, analyzing EMAS (Eco‐Management and Audit Scheme) adoption and patented innovations (at the European Patent Office) at firm level. It uses an original panel database of 30 439 European firms belonging to all sectors from 2003 to 2012. An original instrumental variable is implemented to control for potential endogeneity. The analysis reveals that EMAS adoption is conducive to more innovation at the firm level. The results vary across countries and sectors. In particular, EMAS is positively related to green patents for medium and low technology manufacturing. Copyright © 2017 John Wiley & Sons, Ltd and ERP Environment
A comprehensive genome‐wide analysis of long noncoding RNA expression profile in hepatocellular carcinoma
Authors: Cui Hongxia , Zhang Yunxing , Zhang Qiujie , Chen Wenming , Zhao Haibo , Liang Jun
Published: October 2017

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, especially in East Asia and China. Long noncoding RNAs (lncRNAs) are emerging as critical regulators that may be involved in the development and progression of cancers in humans. However, the contributions of lncRNAs to HCC development, metastasis, and recurrence remain largely unknown. In this study, we comprehensively investigated lncRNA expression profile in HCC and normal tissues using TCGA RNA sequencing data, one RNA sequencing dataset, and two microarray datasets from GEO. By analyzing these four datasets, we identified hundreds of expression‐dysregulated lncRNAs in HCC tissues compared with normal tissues. Genomic copy number variation analysis showed that many of those lncRNAs disorder are related to the copy number amplification or deletion. Moreover, several lncRNAs expression levels are associated with HCC patients' overall and recurrence‐free survival, such as RP1‐228H13.5, TMCC1‐AS1, LINC00205, and RP11‐307C12.11. Furthermore, we identified two lncRNAs termed PVT1 and SNHG7 that may be involved in HCC cells metastasis by comparing lncRNAs expression profiles between early recurrence HCC tissues with metastasis and late recurrence HCC tissues without metastasis. Finally, loss‐of‐function assays confirmed that knockdown of SNHG7 and PVT1 impaired HCC cells invasion. Taken together, these findings may provide a valuable resource for further identification of novel biomarkers and therapeutic targets for HCC patients.
Understanding consumers' purchasing behavior of ethnically disparate products
Authors: Hyun Jonghan , Fairhurst Ann
Published: October 2017

Recent market trends in the USA suggest that an increasing number of consumers are purchasing products associated with disparate ethnic cultures. According to previous research, such behavior is influenced by the consumers' tendency to seek diversity. However, we argue that the drivers of the behavior is yet to be fully identified due to the lack of studies that investigate the specific behavior as a separate phenomenon. That is, most previous studies make no distinction between ethnically congruent and ethnically disparate products, but rather focus on products associated with an ethnic culture in general. Accordingly, we utilize the consumption value theory to develop a model for understanding the consumption of ethnically disparate products. The model is tested by presenting 581 participants with a survey questionnaire that includes a scenario associated with either the Asian culture, the Latin American culture, or the African culture. Structural equation modeling supports the model and suggests that the consumption behavior is influenced by not only the consumers' diversity seeking tendency, but also the consumers' attitude toward the ethnic culture associated with the product, and the value discrepancy between the consumers' own ethnic culture and the ethnic culture associated with the product. Additional tests further show that these effects are moderated by the ethnic‐embeddedness of the product. Implications of the findings for research and practice are discussed.
Pre‐Assembled Coumarin–Rhodamine Scaffold for Ratiometric Sensing of Nitric Oxide and Hypochlorite
Authors: Ong Jun Xiang , Pang Victoria Yu Ting , Tng Li Min , Ang Wee Han
Published: October 2017

A new pre‐assembled ratiometric sensing platform was constructed from a coumarin donor and a rhodamine acceptor designed for through‐bond energy transfer (TBET). A phenylacetylene linker was installed to disrupt the planarity of the extended conjugated system but retaining the efficient energy transfer between the donor and acceptor motifs. To demonstrate its versatility as a sensing platform, we conjugated recognition motifs through amide coupling reactions to yield two TBET chemosensors capable of sensing either endogenously produced NO and ClO−. Both probes possessed high selectivity for their analytes, exhibited good stability under physiological conditions, and performed well as bioimaging probes in living cells.
Ultrathin Anionic Tungstophosphite Molecular Wire with Tunable Hydrophilicity and Catalytic Activity for Selective Epoxidation in Organic Media
Authors: Zhang Zhenxin , Sadakane Masahiro , Hara Michikazu , Ueda Wataru
Published: October 2017

Invited for the cover of this issue are the groups of Zhenxin Zhang and Wataru Ueda at Kanagawa University, Tokyo Institute of Technology, and Hiroshima University. The image depicts the development of a tungstophosphite molecular wire through the growth of a tree, in which the roots represent the triangular PIIIO3 units with tungstate that assemble into the trunk of building blocks and the final wire grows on the branches. Read the full text of the article at 10.1002/chem.201703856.
Dynamic Web information foraging using self‐interested agents: Application to scientific citations network
Authors: Drias Yassine , Kechid Samir
Published: October 2017

In this paper, a dynamic information foraging approach is proposed. Game theory and more precisely normal‐form is adapted to model the addressed problem. We tackle the issue of Web information foraging as a game played by a set of self‐interested agents that aim at reaching relevant Web pages in a short time. We introduce three kinds of agents along with the strategies followed by each one of them. In fact, the actions performed by the agents would highly depend on the strategy they adopt. We propose a pure strategy, a mixed strategy, and a fully mixed strategy respectively for the three kinds of agents. The agents share a common goal, which is satisfying a specific information need and work together in order to achieve it. The cooperative aspect between the self‐interested agents allows to get information from the Web in an effective and efficient way. Furthermore, we discuss the dynamic aspect of our information foraging approach which is ensured thanks to a modular multi‐agent system architecture. In order to test our Web information foraging system, we performed extensive experiments on the Citation Network Dataset that includes more than 2.3 million scientific publications. A preprocessing step was conducted with the aim of classifying the publications according to the 2012 ACM ontology, the purpose being to make our approach scalable. We also compared the results of our approach with two information access approaches. The first one deals with Web information retrieval whereas the second concerns medical information foraging. The experimental results show the superiority of our approach in terms of efficiency and results quality.
Cytokeratin7 expression in histologic and cytologic specimens of cystic neck metastasis from HPV positive squamous cell carcinoma of the tonsil: A case report
Authors: Cho Yong Kyun , Lee Seung Ju , Woo Jeong Joo , Lee Hyekyung , Lee Hojung
Published: October 2017

The majority of cystic squamous cell carcinomas (SCCs) of the neck have been shown to be metastatic tumors from tonsillar SCCs associated with high‐risk human papillomavirus (HR HPV). Recent studies have demonstrated cytokeratin (CK)7 involvement in the development of HPV positive SCC, but no report has been issued on its simultaneous expression in primary tonsillar and metastatic tumor with cystic change. We present a case of HPV positive tonsillar SCC of a 42‐year‐old male that initially manifested as a cystic neck mass expressing CK7, CK19, and p16 in primary and metastatic tumors. Immunohistochemical examination revealed diffuse CK19 and p16 expression, and patchy CK7 expression in the solid components of primary and metastatic tumors. However, in cystic components of metastatic tumors the expression of CK7 and CK19 was preserved but p16 expression was absent, which was consistent with immunocytochemical findings of fine‐needle aspirates from cystic neck mass. In immunocytochemistry performed on aspirates of a branchial cleft cyst for the comparison of cystic SCC and benign cyst, CK19 staining was positive but CK7 and p16 staining was negative. These results suggest that CK7 immunocytochemistry on aspirated material from cystic neck mass may be a useful adjunct for distinguishing cystic metastasis of tonsillar SCC from branchial cleft cyst, although a larger scale study would be required.
Photon Funnels for One‐Way Energy Transfer: Multimetallic Assemblies Incorporating Cyclometallated Iridium or Rhodium Units Accessed by Sequential Cross‐Coupling and Bromination
Authors: Knuckey Kathryn J. , Williams J. A. Gareth
Published: October 2017

The generation of multimetallic assemblies is a widely explored theme, owing to the relevance of controlling energy and electron transfer between metal centres to many fields of contemporary importance. Boronic acid substituted coordination and organometallic complexes have been shown to be useful synthons in the formation of such structures through cross‐coupling with halogenated complexes. In this work we used such a methodology to generate an octanuclear mixed‐metal compound of composition Ir7Ru having a dendrimer wedge‐like structure. The method combined cross‐coupling with regiospecific bromination of phenylpyridine (ppy) ligands at the position para to the C–Ir bond. The propensity of Ir(ppy)2‐based complexes to electrophilic bromination was found to be deactivated by the introduction of fluorine atoms. The coupling methodology was extended to rhodium‐containing systems, exemplified by a tetranuclear system of composition Rh2Ir1Ru1. The synthesis required the use of boronic acid appended RhIII complexes, which could be accessed by the introduction of a neopentyl boronate ester appended bipyridine into the coordination sphere of RhIII. The excited‐state energies of the constituent metal units in the resulting multinuclear complexes are such that unidirectional energy transfer occurs from the RhIII/IrIII branches to the RuII core. The luminescence thus resembles that of an isolated [Ru(bpy)3]2+ unit, but the ability of the structure to collect light is greatly enhanced.
Synthesis, Structures, and Characterization of Dimeric Neutral Dithiolato‐Bridged Tungsten Complexes
Authors: Mondal Bijan , Bag Ranjit , Bakthavachalam K. , Varghese Babu , Ghosh Sundargopal
Published: October 2017

The quadruply bridged bimetallic dithiolato complex [(Cp*W)2(µ‐S)2(µ,η2‐S2CH2)] (3) and the open‐cage triple‐decker complex [(Cp*W)2(µ‐S)(µ‐η4:η4‐B2H2S2)] (2) have been prepared by treatment of CS2with in situ generated [(Cp*W)2(B2H6)2] (1) obtained by the reaction of [Cp*WCl4] with [LiBH4·thf]. The solid‐state X‐ray diffraction structures of these complexes show the presence of doubly bridging η2‐S2B2H2and η2‐S2CH2ligands with a short W–W bond. While many dimolybdenum–sulfur compounds are known, examples of the tungsten–dithilato complexes are relatively few, and in this respect, the isolation of [(Cp*W)2(µ‐S)2(µ,η2‐S2CH2)] represents a rare example of this type. Electronic‐structure analysis, on the grounds of density functional theory (DFT), together with X‐ray diffraction studies, has rationalized the presence of short W–W and B–B bonds. Large HOMO–LUMO gaps have been observed for both compounds, which is consistent with their thermodynamic stability. All of the compounds have been characterized by mass spectrometry, IR spectroscopy, and1H NMR,11B NMR, and13C NMR spectroscopy in solution, and the structural architectures have been unambiguously established by X‐ray diffraction crystallographic analysis.
Weak M···H–C Interactions in Neutral Complexes, Anions and Cations of Palladium(II) and Rhodium(I) Containing the iso‐Quinoline Ligand – Anagostic or Preagostic?
Authors: Sajjad M. Arif , Schwerdtfeger Peter , Harrison John A. , Nielson Alastair J.
Published: October 2017

DFT‐D calculations show that the above‐plane M···H–C separations in square‐planar complexes of PdII and RhI containing the iso‐quinoline ligand are influenced by whether the complexes are neutral, anionic or cationic, due mainly to changes in atomic charge on the metal, H and C atoms, but the nature of the cis‐ligands also plays a part because of the development of weak intramolecular interactions. The Pd···H–C separations are effected by strong σ‐withdrawing or π‐donating substituents placed at C7 of the iso‐quinoline ligand with the shortest anagostic Pd···H separation of 2.218 Å achieved using the π‐donating S– substituent in an anionic complex. The same substituent on the cationic complex leads to Pd–C covalency. Lack of flexibility of the iso‐quinoline ring system prevents the anagostic carbon approaching the metal when the electrostatics are favourable. Instead of an anagostic/preagostic divide, it is suggested that all complexes with above‐plane Pd···H–C close approaches are termed anagostic, and where some agostic covalency develops below an NBO (Natural Bond Order) E(2) value of 5 kcal mol–1 they can be regarded as having an emerging preagostic condition.