bluuebunny/crossref_metadata_2025 huggingface dataset:
Comunicação de saúde: surgimento e consolidação da especialidade = Health communication: emergence and consolidation of specialty
Authors: Bertol Sônia Regina Schena
Published: June 2018

Resumo: A Comunicação da Saúde vem consolidando-se como uma especialidade da sub-área da Comu­nicação Científica e desenvolve-se a partir de idéias disseminadas por médicos europeus ainda no início do século XIX, as quais ganham embasamento epistemológico principalmente nas últimas três décadas, quando novos paradigmas surgidos na comunicação e na saúde passam a perceber a ne­cessidade da união das duas áreas, considerando os pressupostos de novas definições conceituais que passaram a considerar principalmente a promoção e a prevenção da saúde. Neste estudo, nos va­lemos principalmente da análise de documentos, resgatados através de duas fontes principais: livros, jornais, newsletters e revistas especializados na área e Internet, caracterizando nossa pesquisa como bibliográfica e documental, segundo as técnicas e os instrumentos de observação, encarando este material bibliográfico e documental como um veículo de observações feitas por outros pesquisadores; e monográfica, quanto ao método, já que pretende analisar verticalmente, ou seja, em profundidade, a questão do surgimento e da consolidação da Comunicação da Saúde.Palavras-chave: Comunicação da saúde; Especialidade; Promoção; Prevenção.Abstract: Health communication comes consolidating itself as a specialty of the sub-area of scientific commu­nication and develops ideas disseminated by European doctors even in the early 19th century, which earn epistemological know-how especially in the last three decades, when new paradigms emerged in communication and health began to realize the need for the union of the two areas, considering the assumptions of new conceptual definitions to consider mainly the promotion and health prevention. In this study, we mainly document analysis worth, rescued by two main sources: books, newspapers, newsletters and magazines specialized in area and Internet, featuring our bibliographic and documentary research, according to the techniques and observation instruments, viewing this documentary and bibliographic material as a vehicle of comments made by other researchers; and Mon., regarding the method, since analyzes vertically, that is, in depth, the question of the emergence and the consolida­tion of Health Communication.Keywords: Health communication; Specialty; Promotion; Prevention.
Las apps en la identidad digital hospitalaria: implicaciones en la reputación y tendencias = Apps in hospital digital identity: implications on reputation and trends
Authors: González Pacanowski Toni , Medina Aguerrebere Pablo
Published: June 2018

Resumen: La internacionalización y la competitividad creciente que caracterizan al sector hospitalario español han llevado a varios centros hospitalarios a potenciar su comunicación institucional como método para mejorar su reputación y así consolidar su posición en el mercado. Entre todas las iniciativas, destaca la apuesta por las apps de contenido médico cuyo objetivo es mejorar la relación establecida con el paciente. El objetivo de este artículo es estudiar el impacto de las apps de salud en la reputación de los hospitales. Para ello, se realiza una revisión bibliográfica y un trabajo de campo sobre apps estables im­pulsadas en el ámbito hospitalario en España. Dichas apps aportan valor a la reputación cuando difun­den información útil para el paciente, se orientan a las prioridades asistenciales del hospital y respetan la confidencialidad y la seguridad. (Investigación vinculada al Plan Nacional CSO2016-81882-REDT).Palabras clave: hospital; comunicación institucional; reputación; marca; Internet; app.Abstract: The internationalization and the increasing competitiveness that characterize the Spanish hospital sec­tor have led several hospitals to enhance their corporate communication as a method to improve their reputation and thus consolidate their position in the market. Among all initiatives, the emphasis is on medical apps whose goal is to improve the relationship established with the patient. This paper aims to study the impact of health apps on the hospitals’ reputation. To do this, we carried out a literature review and a fieldwork about the apps of the mains Spanish hospitals. The main conclusion is that apps add value to reputation when they disseminate information that is useful to the patient, responds to hospital care priorities and respects confidentiality and security.Keywords: hospital; corporate communication; reputation; Brand; Internet; app.
Análisis de estafas de pacientes en la prensa española. El caso de Paco Sanz, el hombre de los 2.000 tumores y el caso de Nadia, la niña con tricodistrofia = Analysis of false patient cases in the Spanish press. Paco Sanz’s case, the man affected by 2,000 tumors and Nadia’s case, the girl with trichodystrophy
Authors: López Villafranca Paloma
Published: June 2018

Resumen: Organizados en asociaciones y con el apoyo de la ciudadanía, los pacientes con enfermedades raras han conseguido ser visibles y lograr mayor inversión en investigación gracias a las donaciones económicas. Sin embargo, ha sido muy perjudicial para estos pacientes la existencia de casos como los de Nadia, la niña con tricodistrofia que sus padres utilizaron para vivir de la enfermedad y el caso del hombre de los 2.000 tumores, un paciente que exageró un síndrome para recaudar 100.000 euros para un tratamiento que no existía. El objetivo principal de la investigación es analizar la difusión de ambas estafas en prensa. Realizamos análisis de contenido en prensa en los tres diarios de mayor difusión según el OJD en el momento de la investigación: El País, El Mundo y La Vanguardia. Mediante este estudio comprobamos cómo la utilización de titulares, palabras e imágenes negativas se relacionan con estas enfermedades y no se da importancia a las fuentes sanitarias y a los pacientes afectados.Palabras clave: enfermedades raras; pacientes; imagen; estafa; prensa.Abstract: Organized by associations and with the support of citizens, patients with rare diseases have managed the increase of scientific research about their diseases provided by private donations. However, it has been very harmful for these patients the latest news about Nadia, the girl with trichodystrophy used by her parents to live from this disease and press news about the man with 2,000 tumors, a patient who exaggerated a syndrome to collect 100,000 euros for a treatment that did not exist. The main objective of the investigation is to analyze the diffusion of both news in Spanish press. We carried out content analysis in press in three newspapers according to OJD, (Spanish Office of Justification of Dissemination): El País, El Mundo and La Vanguardia. We verified the use of headlines, negative words and negative images are linked to these diseases and it is not taken into account sanitary sources and patients sources.Keywords: rare diseases; patients; image; fraud; press.
Importancia de la comunicación en el establecimiento y satisfacción con el tratamiento en fisioterapia = Importance of communication in the establishment and satisfaction with physiotherapy treatment
Authors: Rodríguez Nogueira Oscar , Morera Balaguer Jaume , Moreno Poyato Antonio , López Rodríguez Ana Felicitas
Published: June 2018

Resumen: Introducción: La fisioterapia ha comenzado a adoptar rápidamente un modelo biopsicosocial donde se reconoce al paciente y su contexto general. Bajo este nuevo paradigma, la comunicación centrada en la persona entre los profesionales de la salud y los beneficiarios de sus cuidados es una de las claves del éxito terapéutico. Objetivo: describir y reflexionar acerca de la importancia de la comunicación centrada en la persona en el establecimiento y satisfacción con el tratamiento en el ámbito de la fisioterapia. Material y métodos: Se ha realizado una revisión bibliográfica sobre la comunicación centrada en la persona entre el fisioterapeuta y el paciente en las bases de datos de ciencias de la salud PEDro y Pubmed, seleccionándose los artículos que se adecuaban a los objetivos del trabajo. Se integró posteriormente la información de los artículos seleccionados junto a los conocimientos y experiencia de los autores en la materia. Conclusiones: La comunicación centrada en la persona es el vehí­culo mediante el cual se mejora la alianza terapéutica, facilitando un papel activo del paciente en la toma de decisiones terapéuticas y mejorando la satisfacción de este con el tratamiento y con los resultados clínicos. Es necesaria la creación de un instrumento de medida de dicha comunicación en el ámbito de fisioterapia.Palabras clave: fisioterapia; comunicación; relación terapéutica; tratamiento; satisfacción.Abstract: Introduction: Physiotherapy is fast adopting a biopsychosocial patient-centred approach where the patient is re­cognized and its general context. Under this new paradigm, the person-centered communication between health professionals and the beneficiaries of their care is one of the keys to therapeutic success. Objective: to descri­be and reflect on the importance of person-centered communication in the establishment and satisfaction with treatment in the field of physiotherapy. Material and methods: A bibliographic review of the person-centered com­munication between the physiotherapist and the patient was carried out in the main databases of health sciences: PEDro, Pubmed, selecting articles that fit the objectives of the study, integrating subsequently the information of the selected articles and the knowledge and experience of the authors in the matter. Conclusions: Patient-centered communication is the vehicle through which the therapeutic alliance is improved, facilitating an active role of the patient in making therapeutic decisions and improving patient satisfaction with treatment and clinical outcomes. It is necessary to create an instrument to measure such communication in the field of physiotherapy.Keywords: physiotherapy; communication; therapeutic relationship; treatment; satisfaction.
Comunicando el Cambio Climático desde un Encuadre de Salud = Communicating Climate Change from a Health Frame
Authors: Cáceres Pinto José Daniel
Published: June 2018

Resumen: Organismos internacionales coinciden que el cambio climático representa una amenaza para el ser humano, particularmente para su salud. Entidades como la Organización Mundial de la Salud (OMS) y voces de la comunidad científica han venido advirtiendo sobre los efectos que las distor­siones climáticas están teniendo sobre la propagación de enfermedades cuyos vectores dependen de su entorno. Sectores vitales para el desarrollo social como la distribución del agua, la agricultu­ra, y la sanidad pública se están viendo cada vez más amenazados por la vorágine climatológica. Sin embargo, persiste una indiferencia silenciosa en diferentes segmentos sociales que consideran el Cambio Climático como un problema abstracto o simplemente algo muy sobre sus capacidades de resolución. Desactivar este desafecto, concienciar a la población general y movilizar a la toma de acción han sido unos de los retos que diversos actores sociales han asumido. Uno de los casos de éxito que más llama la atención ha sido el uso de encuadres de salud. El siguiente artículo di­secciona el impacto que el Cambio Climático tiene y presenta el caso sobre el uso de la promoción de la salud en EEUU para concienciar sobre la problemática ambiental.Palabras clave: Salud; Cambio Climático; encuadres; mensaje.Abstract: International organizations agree that climate change poses a threat to the human being, parti­cularly to his health. Entities such as the World Health Organization (WHO) and voices from the scientific community have been warning about the effects the climatic distortions are having on the propagation of illnesses which vectors depend on their surroundings. Vital sectors for social development such as water distribution, agriculture, and public health are progressively seeing themselves more threatened by the climatic maelstrom. Nevertheless, an indifferent silence per­sists in different social segments who consider Climate change as an abstract problem or simply something out of their reach to resolve. Deactivating this disaffection, raising awareness in the ge­neral population and mobilize to take action have been some of the challenges social actors have undertaken. One particular success story that grabs the attention is the use of health frames. The following article dissects the impact that Climate Change has and presents the case of the use of health promotion in the USA to raise awareness about the environmental problem.Keywords: Health; Climate Change; Frames; Message.
O efeito mediador das capabilidades da tecnologia e sistema de informação na relação entre gestão da cadeia de suprimentos e desempenho competitivo
Authors: Vitorino Filho Valdir Antonio , Moori Roberto Giro
Published: June 2018

O objetivo deste artigo foi identificar o efeito mediador das Capabilidades da Tecnologia e Sistemas de Informação (CapT-SI) na relação entre Gestão da Cadeia de Suprimentos (GCS) e Desempenho Competitivo (DC). Para tanto, como metodologia, utilizou-se do método misto. Na fase qualitativa, foram coletados dados junto a uma amostra de 10 empresas e tratadas pela análise de conteúdo. Na fase quantitativa, a coleta de dados se deu em uma amostra de 125 empresas e tratadas pela estatística multivariada. Em ambas as fases, as amostras foram compostas de empresas dos polos tecnológicos brasileiros. Os resultados revelaram que as CapT-SI medeiam totalmente, a relação entre GCS e o DC. Diante disso, pode-se concluir que as CapT-SI tem papel importante para a integração e DC das empresas dos polos tecnológicos.
Análise organizacional sob a ótica da teoria da complexidade: proposição e aplicação de um modelo
Authors: Ramalho Wanderley , Locatelli Ronado Lamounier , Domingos Silva Shirlei da Conceição
Published: June 2018

O objetivo deste artigo foi desenvolver um modelo de gestão organizacional sob a ótica da Teoria da Complexidade, que permitisse verificar a existência de uma administração complexa. Tal desenvolvimento exigiu o exame da Teoria da Complexidade e a criação de construtos que permitam identificar tais características em um empresa. O estudo procedeu à aplicação do modelo criado em uma realidade organizacional objetivando verificar se a mesma apresentava características dessa teoria. A metodologia utilizada foi de natureza qualitativa, do tipo exploratória e descritiva. A unidade de análise foi a Empresa Beta (nome fictício) e a unidade de observação foi constituída por 28 funcionários ocupantes de cargos de liderança. A coleta de dados se deu por meio de entrevistas semiestruturadas e semidiretivas e a técnica de análise foi a análise de conteúdo. O método permitiu concluir que, com base na percepção dos funcionários entrevistados, existem características de uma administração complexa na organização. Assim, o empenho colocado neste artigo visa contribuir para preencher a lacuna explicitada pela empiria, que carece de um novo modelo de gestão estribado nos requisitos do nascente paradigma da complexidade.
Editorial
Authors: Lara José Edson
Published: June 2018

One of the many terms that have been assumed and used in the scientific academia has been the "publisch or perish". Although it originates in the academic world of the United States, its approach has been intensifying in Brazil.The concept refers to and induces the compulsion for publications, usually intensive and uncreative, often on repetitive and at most incremental to the literary knowledge. Rare, therefore, are effectively innovative productions, in epistemic, conceptual, and morphological logics.
Editorial
Authors: Lara José Edson
Published: June 2018

Uno de los muchos términos que vienen siendo asumidos y utilizados en la academia há sido el "publisch or perish". Aunque es originario del medio académico de los Estados Unidos, su enfoque se está intensificando en Brasil.El concepto se refiere e induce a la compulsión por publicaciones, en general intensivas ya menudo poco creativas, frecuentemente sobre conocimientos repetitivos y, como máximo, incrementales a las literaturas. Raras, por lo tanto, son las producciones efectivamente innovadoras, en las lógicas epistémicas, conceptuales y morfológicas.
Analysis on Administrative Services in Dental Poly Clinic PLK Unair 2017
Authors: Kerina Jaqueline
Published: June 2018

Service delivery and healthcare have recently received increasing attention. Pusat Layanan Kesehatan Universitas Airlangga (PLK UNAIR) is in a network with various hospitals and government insurance agencies in assurance of best healthcare service for the community. The objective of this study is to describe the flow of the administrative services in the dental unit of PLK UNAIR. This study followed qualitative design approach and study was explorative through active participation, conducted interviews and observations. Results drawn from this study showed that the flow of administrative services, PLK UNAIR has accomplished its objectives through the contribution of its employees. The summary shows the identification of patient flow in PLK UNAIR dental unit. It is evident that PLK receives a high influx of patients a lot that happens to be students and at a friendly rate. Keywords: administration, patients, services and students.
Pencapaian Standar Nasional Pelayanan Kesehatan Peduli Remaja pada Posyandu Remaja di Surabaya
Authors: Ningsih Fitriani Putri Eka
Published: June 2018

Since 2010 Surabaya has teenage integrated service post (Posyandu) to solve teenagers’ problem, but there were still a lot teenagers’ problem in Surabaya include early marriage. This study aims to determine about National Standard achievement of teenagers health care service at integrated service post in Surabaya. This research used cross sectional design with qualitative descriptive approach. The interview was conducted in 15 teenage integrated service post in Surabaya, and the respondent wasthe coordinator of teenage integrated service post. Result showed that assessment of teenage and networking standard are difficult to achieve. That was related to teenagers’ interest and socialization which is not well organized. Also, there was no specific guidelines for teenagers so the officers should guess and make their own guidelines. There were a lot teenage integrated service post in Surabaya did not have completed filing and did not record and report their activities. The lack of health management in teenage integrates service post influence the achievement of PKPR National Standard. Keywords: health care service, integrated service, National standard, teenage.
Perencanaan Tenaga Teknis Kefarmasian Berdasarkan Analisis Beban Kerja Menggunakan Metode WISN di RSIA KM
Authors: Yulaika Nurul
Published: June 2018

Human Resources is one of the central factors that drive quality hospital services. Human Resource Planning of pharmaceutical technicians at RSIA KM posed risks to service performance. The objective of this cross sectional study was to analyze the pharmacy staff requirements and workload using Workload Indicators of Staffing Need (WISN) method based on real time activity standards for each workload. RSIA KM had 4 existing pharmacy technicians. Based on the WISN analysis, the results of the study should WISN ratio 0.49 or ≤ 1.00 which means there was a lack of pharmaceutical staff. The ideal number of pharmaceutical staff should be 8.08 or 8 staff. In response, RSIA KM recruited 4 pharmacy technicians. Implication for job enrichment and recruitment are discussed. Keywords : human resource planning, WISN (workload indicators of staffing need), pharmaceutical technical staff
JOGOS DIGITAIS MULTIMODAIS E RPG: Experiências no desenvolvimento da consciência ambiental a partir de recursos educacionais lúdicos
Authors: Ferrari Barbosa Débora Nice , Martins Rosemari Lorenz , Junior Norberto Khun
Published: June 2018

Este trabalho apresenta experiências com o desenvolvimento e aplicação de um jogo digital multimodal e de um RPG (Role-playing game) na motivação e engajamento de alunos para o uso sustentável da água e dos recursos hídricos. O projeto envolveu alunos dos anos finais do Ensino Fundamental e Ensino Médio de uma escola privada e de uma escola pública da região do Vale do Rio dos Sinos. Os resultados obtidos demonstram que a aprendizagem a partir da prática pedagógica aplicada envolvendo dispositivos móveis, bem como as interações no jogo digital multimodal, melhorou a compreensão dos alunos quanto a sua própria consciência ambiental, estimulando a colaboração e auxiliando na compreensão de conceitos-chave que envolve o tema.
AS INTERVENÇÕES ARTÍSTICAS URBANAS NO CIRCUITO DA ARTE EM RORAIMA E O POTENCIAL COMUNICATIVO DOS SABERES ARTÍSTICOS AMAZÔNICOS
Authors: Baptaglin Leila Adriana , Chierentin Santi Vilso Junior
Published: June 2018

Discutir como as intervenções artísticas urbanas comunicam ao expectador Roraimense apresenta-se como o foco de discussão deste estudo.. Para dar conta desse objetivo, foram realizadas investigações teóricas pautadas na compreensão do cenário artístico contemporâneo, a partir dos estudos de Cauquelin (2005) e Cocchiarale (2004); e das especificidades roraimense, dando destaque à representação artística dos saberes locais, com os estudos de Gonçalves (2017) e Silva (2017). Em paralelo, trabalhamos com a apropriação dos conceitos de circuito da cultura de Johnson (1999) e Nessbaumer (2000), no sentido de estabelecer uma proposta de discussão acerca do que chamamos Circuito da arte. Este circuito nos possibilita entender os processos pelos quais a produção artística passam até chegar ao consumo pelo expectador. Desta forma, podemos perceber que a comunicação expressa pelas intervenções artísticas urbanas ainda é bastante insipiente, no que se refere a apropriação artística dos saberes locais roraimenses e amazônicos.
PROPAGANDA ELEITORAL NAS NOTÍCIAS: interfaces entre jornalismo e Programa Eleitoral Gratuito nas eleições para o governo do Maranhão
Authors: Sousa Li-Chang Shuen Cristina Silva
Published: June 2018

O artigo traz os resultados referentes ao eixo “Telejornalismo e HGPE” da pesquisa Mediatização das Eleições de 2014 no Maranhão, cujo objetivo geral é identificar os padrões discursivos de construção da viabilidade eleitoral e capital político do candidato Edson Lobão Filho (PMDB) ao governo estadual. O objetivo deste paper específico é estudar a permeabilidade entre a lógica política propagada no HGPE-Lobão Filho e o discurso político-jornalístico do JMTV1, partindo-se da hipótese de que o telejornal e o programa do horário eleitoral se complementaram tanto em relação ao conteúdo (pautas) quanto em relação à estética (formato do conteúdo), constituindo-se, ambos, uma única peça publicitário-eleitoral, sendo uma explícita (o HGPE) e outra velada (JMTV1).
“QUEM DEIXOU ISSO AQUI?!”: Retórica procedimental e participação no desenvolvimento de um jogo em saúde
Authors: Vasconcellos Marcelo Simão , Carvalho Flávia Garcia de , Araújo Inesita Soares de
Published: June 2018

Este trabalho explora a abordagem da retórica procedimental e o conceito de jogos como participação aplicados a um jogo sério (serious game) voltado para a comunicação em saúde. A partir da experiência do desenvolvimento do jogo “Quem Deixou Isso Aqui?!”, voltado para a conscientização de pais e responsáveis sobre os riscos de intoxicações domésticas em crianças, apresentamos a retórica procedimental como forma de construção de sentido nos jogos digitais aliada aos domínios de participação do jogador, descrevendo como tais conceitos teóricos impactam os aspectos estéticos, textuais, técnicos e procedimentais de um jogo de comunicação em saúde.
The Development of Cartographical Studies and Praxis in Montenegro
Authors: Nikolic Gojko , Spalevic Velibor , Susic Zoran , Batilovic Mehmed , Skataric Goran , Bozovic Ruzica , Djurovic Radovan , Vuckovic Dragan
Published: June 2018

This paper deals with an analysis of cartographical studies, the real estate cadastre, and its practical implementation, as well as the introduction of cartography into different education modules in university-level studies in Montenegro. There is a discussion of the development, production, and creativity in the fields of cartography and real estate cadastre over time, cartographical projection, scientific results, and recent changes such as advanced computer- and satellite-based technologies, GIS, cartographical visualization, and digital cartography. The impact of these changes on cartographical studies at the University of Montenegro is considered. Particular attention is given to analyses of cartography and the cadastre in institutions, and their connection with the development of cartography teaching modules of Geography, Geodesy and Geoinformatics at the University of Montenegro. The integrated analysis also covers the results of the questionnaire and the significance of the geo-topographical and cartographical heritage of Montenegro, with the aim of carrying these out. It can be seen that the tasks solved by using maps have tended to become more complex and that the cartographical methods employed in this have been always directed towards Montenegro’s most prominent and most urgent problems, including those that appear in the area of education.
Generation-common and -specific factors in intention to leave among female hospital nurses: A cross-sectional study using a large Japanese sample
Authors: Tei-tominaga Maki , Asakura Kyoko , Asakura Takashi
Published: June 2018

An understanding of the cultural conditions that determine the factors affecting nurses’ intention to leave is important for countries suffering from nurse shortage. Aim: to examine factors influencing intention to leave among female hospital nurses in a large Japanese sample, classified into four generations by age considering economic conditions. Methods: a cross-sectional survey with convenience sampling was conducted. Anonymous self-administered questionnaires were distributed to all nurses in 30 hospitals. To assess intention to leave, basic attributes, life conditions, work characteristics, and factors of psychosocial work environment were addressed. After classifying data into four generations based on age cohorts, we conducted multivariate logistic regression analysis using the completed data (N = 5,074, mean age = 36.24). Results: regardless of generational characteristics influenced by economic conditions, effort and monetary reward were generation-common factors. Over-commitment, social support, and the presence of a role model were generation-common factors in three generations. While having children increased intention to leave in the generation born 1965–1979, having family members in need of caregiving other than children decreased the risk in the generation born in the 1980s. Conclusion: generational countermeasures considering factors of psychosocial work environment and life conditions are needed to avert female nurse turnover.
Developmental- and tissue-specific changes of ubiquitin forms in Drosophila melanogaster.
Authors: Nagy Ágota , Kovács Levente , Lipinszki Zoltán , Pál Margit , Deák Péter
Published: June 2018

In most Eukaryotes, ubiquitin either exists as free monoubiquitin or as a molecule that is covalently linked to other proteins. These two forms cycle between each other and due to the concerted antagonistic activity of ubiquitylating and deubiquitylating enzymes, an intracellular ubiquitin equilibrium is maintained that is essential for normal biological function. However, measuring the level and ratio of these forms of ubiquitin has been difficult and time consuming. In this paper, we have adapted a simple immunoblotting technique to monitor ubiquitin content and equilibrium dynamics in different developmental stages and tissues of Drosophila. Our data show that the level of total ubiquitin is distinct in different developmental stages, lowest at the larval-pupal transition and in three days old adult males, and highest in first instar larvae. Interestingly, the ratio of free mono-ubiquitin remains within 30-50% range of the total throughout larval development, but peaks to 70-80% at the larval-pupal and the pupal-adult transitions. It stays within the 70-80% range in adults. In developmentally and physiologically active tissues, the ratio of free ubiquitin is similarly high, most likely reflecting a high demand for ubiquitin availability. We also used this method to demonstrate the disruption of the finely tuned ubiquitin equilibrium by the abolition of proteasome function or the housekeeping deubiquitylase, Usp5. Our data support the notion that the ubiquitin equilibrium is regulated by tissue- and developmental stage-specific mechanisms.
Human Consequences of Multiple Nuclear Detonations in New Delhi, India
Authors: Desai Samir , Bell William , Harris Curtis , Dallas Cham
Published: June 2018

The human casualties from simulated nuclear detonation scenarios in New Delhi, India are analyzed, with a focus on the distribution of casualties in urban environments and the theoretical application of a nuclear-specific triage system. Model estimates of nuclear war casualties employed ESRI's ArcGIS 9.3, blast and prompt radiation were calculated using the Defense Nuclear Agency's WE program, and fallout radiation was calculated using the Defense Threat Reduction Agency's (DTRA's) Hazard Prediction and Assessment Capability (HPAC) V404SP4, as well as custom GIS and database software applications. ESRI ArcGISTM programs were used to calculate affected populations from the Oak Ridge National Laboratory's LandScanTM 2007 Global Population Dataset for areas affected by thermal, blast and radiation data.  Trauma, thermal burn, and radiation casualties were thus estimated on a geographic basis for New Delhi, India for single and multiple (six) 25 kiloton (kt) detonations and a single 1 megaton (1000kt) detonation. Major issues related to the emergency management of a nuclear incident are discussed with specific recommendations for improvement.  The consequences for health management of thermal burn and radiation patients is the worst, as burn patients require enormous resources to treat, and there will be little to no familiarity with the treatment of radiation victims.
Vitamin C to Improve Organ Dysfunction in Cardiac Surgery Patients—Review and Pragmatic Approach
Authors: Hill Aileen , Borosch Sebastian , Benstöm Carina , Neubauer Christina , Meybohm Patrick , Langlois Pascal , Adhikari Neill KJ , Heyland Daren K , Stoppe Christian
Published: June 2018

The pleiotropic biochemical and antioxidant functions of Vitamin C (Vit C) have recently sparked interest in its application in intensive care. Vit C protects important organ systems such as the cardiovascular, neurologic and renal system during inflammation and oxidative stress. Vit C also influences the systems of coagulation and inflammation and its application might prevent the development of organ damage. The current evidence of Vit C’s effect on the pathophysiological reactions during various acute stress events, such as sepsis, shock, trauma, burn and ischemia-reperfusion injury imposes the question, if the application of Vit C might be especially beneficial for cardiac surgery patients, who are routinely exposed to ischemia/reperfusion and subsequent inflammation, systematically affecting different organ systems. This review covers current knowledge about the role of Vit C in cardiac surgery patients with focus on its influence on organ dysfunctions. The relationships between Vit C and clinical health outcomes are reviewed with special emphasis on its application in cardiac surgery. Additionally, this review pragmatically discusses evidence regarding the administration of Vitamin C in every day clinical practice, tackling the issues of safety, monitoring, dosage and most the appropriate application strategy.
HOSPITAL ENVIRONMENTAL PERFORMANCE COMPARISON IN WASTE MANAGEMENT IN JAKARTA
Authors: Basoeki Soegeng , Putrawan I Made , Setiawati Susy
Published: June 2018

This study is a survey of the performance of the hospital environment in the field of waste management. Survey was conducted in RS. Cipto Mangunkusumo, RS. Persahabatan and RSPI Sulianti Saroso. Environmental performance of the Hospital would be good if 1) has sufficient human resources, budget management and have good facilities and adequate environmental technologies 2) Environmental regulations adhered to apply quality standards.  The budget for the maintenance of waste management facilities and the recruitment of human resources outsourcing needs to be improved. Efforts to increase the motivation of the human resources environment also needs to be done in order to achieve predetermined performance targets
¿LA NECESARIA REGULACIÓN “AD HOC” DE LAS VIVIENDAS VACACIONALES? El caso de Canarias
Authors: GONZÁLEZ CABRERA INMACULADA
Published: June 2018

En los últimos años se ha producido un auge en la explotación de viviendas con fines vacacionales. A él ha contribuido el desarrollo de Internet y la aparición de múltiples plataformas digitales que acercan a oferentes y demandantes. Esta oferta, hasta ahora al margen de los canales tradicionales de comercialización en masa del alojamiento turístico, nos plantea serias dudas acerca de cómo afrontar su regulación. Esto es, si ha de hacerse necesariamente mediante una reglamentación propia o si habrá que incorporarla a la regulación del resto de los alojamientos turísticos, sobre todo en aquellas Comunidades Autónomas que han afrontado dicha ordenación. El presente trabajo aborda esta cuestión centrándose en la regulación contenida en el Decreto 113/2015, de 22 de mayo, de Viviendas Vacacionales, ordenación ésta que analizaremos de forma crítica sobre la base del reproche que se le ha hecho por los propietarios y por la Comisión Nacional de los Mercados y de la Competencia, así como, por los recientes pronunciamientos del Tribunal Superior de Justicia de Canarias.
Entropies in investigation of dynamical systems and their application to digital image analysis
Authors: Ampilova Natalia , Soloviev Igor
Published: June 2018

We discuss entropy characteristics used in various research techniques for investigation of complex dynamical systems including symbolic ones. The dynamics of a system may be studied by analyzing the phase portrait of a system obtained as a digital image. Symbolic dynamics methods allow combining entropy of a given dynamical system with the entropy characteristics of its phase portrait. We apply methods of image analysis based on symbolic dynamics, Rényi entropy, fractal and multifractal characteristics to analyze high resolution images having a complex structure. We also describe the results of applications of described methods to images of biomedical preparations.
Mathematical solutions for the flexural analysis of Mindlin’s first order shear deformable circular plates
Authors: Chinwuba Ike Charles
Published: June 2018

In this work, the problem of first order shear deformable solid circular plate under transverse load was solved mathematically. The problem considered was assumed axisymmetric. The plate and loading were considered axisymmetric. The problem was defined as a boundary value problem of a system of differential equations of equilibrium in terms of the stress resultants and the stress – resultants – displacement relations. The set of equations were considered simultaneously to express them in variable separable form. The mathematical technique of separation of variables was then used to obtain solutions for the unknown generalised displacements. Specific problems of clamped edge plates and simply supported edge plates under uniformly distributed load and point load at the centre were considered and solved using the same technique of separation of variables. The mathematical expressions obtained showed that in all cases, the deflection was expressible in terms of flexural and shear components. The maximum deflection was found to occur at the plate centre as is expected from the symmetrical nature of the problem. The shear component of the transverse deflection was found to significantly increase with significant increase in the ratio of the plate thickness to the radius (h/r0).
Research on performance prediction and optimization of road header based on regression model
Authors: Qin Yanan , Yuan Yongyue
Published: June 2018

The drilling rate is one of the key parameters to measure the working performance of the road header. Set the drilling speed as the target variable, the quadratic regression model is established by using the master control parameters, such as cutter head torque, jack thrust, cutter head speed, and screw speed as design variables, then the prediction function of the drilling speed is obtained. The error of the regression function is determined by the fitting coefficient of determination, the modified coefficient of determination and the root mean square error, then the effect of different sample data mining methods on the fitting accuracy is studied. An optimization mathematical model is constructed. The quadratic programming algorithm is applied to solve the extreme values under different sample numbers, therefore, the tunneling performance is effectively improved. The research method has high computational efficiency, and the theoretical results are reliable.
Rainfall and runoff characteristics in a karstic basin of China
Authors: Mo Chongxun , Mo Guiyan , Qin Junkai , Zhou Ming , Yang Qing , Huang Ya , Yang Yunchuan
Published: June 2018

This paper examines the rainfall and runoff characteristics in a karstic basin of China. The results indicated that the inner-annual distributions of rainfall and runoff were uneven and slightly different, as the concentration period of rainfall (from April to October) was earlier; there was a delay of about a month before the runoff (from May to September), and the concentrated volume accounted for 87% of annual precipitation or annual streamflow. Interannually, rainfall changed more significantly than runoff, the wet years lasted longer than the dry years (rainfall), while the high and low flow years were equal for runoff. In addition, judging from the value of the Mann-Kendall test, the average annual change of rainfall (−2.36) was more significant than that of runoff (−2.05), and the seasonal pattern of runoff maintained an opposite tendency in autumn and winter before 1990. The changes in runoff were mainly associated with rainfall and the formation conditions in the karstic area, and the reservoir in this basin should be operated with different flood limiting water levels, and the vegetation coverage should be improved.
Latest Updates in Dengue Fever Therapeutics: Natural, Marine and Synthetic Drugs
Authors: Hosseini Samira , Muñoz-Soto Rodrigo B. , Oliva-Ramírez Jacqueline , Vázquez-Villegas Patricia , Aghamohammadi Nasrin , Rodriguez-Garcia Aida , Martinez-Chapa Sergio O.
Published: June 2018

In this paper, we review the history of Dengue, the mechanism of infection, the molecular characteristics and components of Dengue, the mechanism of entry to the target cells, cyclization of the genome and replication process, as well as translation of the proteins for virus assembly. The major emphasis of this work is on natural products and plant extracts, which were used for as palliative or adjuvant treatment of Dengue. This review article also summarizes the latest findings in regards to the marine products as effective drugs to target different symptoms of Dengue. Furthermore, an update on synthetic drugs for treating Dengue is provided in this review. As a novel alternative, we describe monoclonal antibody therapy for Dengue management and treatment.
Roles of Cyclooxygenase, Prostaglandin E2 and EP Receptors in Mucosal Protection and Ulcer Healing in the Gastrointestinal Tract
Authors: Takeuchi Koji , Amagase Kikuko
Published: June 2018

Endogenous prostaglandins (PGs), produced from arachidonic acid by the two isoforms of
cyclooxygenase (COX), play a pivotal role in maintaining mucosal integrity by modulating various functions of
the gastrointestinal (GI) tract, and PGE2 is most effective in these actions. The PGE2 receptor is classified into 4
specific G-protein coupled subtypes, EP1-EP4, and their distribution accounts for the multiple effects of this
prostanoid. PGE2 prevents acid-reflux esophagitis and indomethacin-induced gastric lesions through EP1
receptors, while endogenous PGs protect the stomach against cold restraint stress mediated by mainly PGI2/IP
receptors and partly EP4 receptors. PGE2 also exhibits a protective effect against acid-induced duodenal damage
and indomethacin-induced small intestinal lesions mediated by EP3/EP4 receptors; these effects in the stomach,
duodenum, or small intestine are associated functionally with inhibition of gastric contraction (EP1), stimulation
of duodenal HCO3
- secretion (EP3/EP4), or suppression of bacterial invasion due to the inhibition of intestinal
motility (EP4) as well as stimulation of mucus secretion (EP3/EP4), respectively. PGE2 also prevents ischemiainduced
enteritis and dextran sulfate sodium-induced colitis mediated by EP4 receptors, and the protective
mechanisms may be related to the stimulation of mucus secretion and the down-regulation of immune response,
respectively. Furthermore, PGE2 shows a healing-promoting effect on gastric ulcers and small intestinal lesions
through the up-regulated expression of vascular endothelial growth factor (VEGF) and stimulation of
angiogenesis via the activation of EP4 receptors. Finally, COX-1 is mainly responsible for the production of
endogenous PGs involved in mucosal protection, while COX-2 is mainly responsible for those involved in the
healing of gastric ulcers or small intestinal lesions. These findings contribute to future development of new
strategies for the treatment of GI diseases.
Interactions of Vascular Endothelial Growth Factor and p53 with miR-195 in Thyroid Carcinoma: Possible Therapeutic Targets in Aggressive Thyroid Cancers
Authors: Maroof Hamidreza , Irani Soussan , Arianna Armin , Vider Jelena , Gopalan Vinod , Lam Alfred King-yin
Published: June 2018

Background:

The clinical pathological features, as well as the cellular mechanisms of
miR-195, have not been investigated in thyroid carcinoma.

Objective:

The aim of this study is to identify the interactions of vascular endothelial growth factor
(VEGF), p53 and miR-195 in thyroid carcinoma. The clinical and pathological features of miR-195
were also investigated.

Methods:

The expression levels of miR-195 were identified in 123 primary thyroid carcinomas, 40
lymph nodes with metastatic papillary thyroid carcinomas and seven non-neoplastic thyroid tissues
(controls) as well as two thyroid carcinoma cell lines, B-CPAP (from metastasizing human papillary
thyroid carcinoma) and MB-1 (from anaplastic thyroid carcinoma), by the real-time polymerase
chain reaction. Using Western blot and immunofluorescence, the effects of exogenous miR-195 on
VEGF-A and p53 protein expression levels were examined. Then, cell cycle and apoptosis assays
were performed to evaluate the roles of miR-195 in cell cycle progression and apoptosis.

Results:

The expression of miR-195 was downregulated in majority of the papillary thyroid carcinoma
tissue as well as in cells. Introduction of exogenous miR-195 resulted in downregulation of
VEGF-A and upregulation of p53 protein expressions. Upregulation of miR-195 in thyroid carcinoma
cells resulted in cell cycle arrest. Moreover, we demonstrated that miR-195 inhibits cell cycle
progression by induction of apoptosis in the thyroid carcinoma cells.

Conclusion:

Our findings showed for the first time that miR-195 acts as a tumour suppressor and
regulates cell cycle progression and apoptosis by targeting VEGF-A and p53 in thyroid carcinoma.
The current study exhibited that miR-195 might represent a potential therapeutic target for patients
with thyroid carcinomas having aggressive clinical behaviour.
Determination of Monoaromatic Hydrocarbons in Water Samples by Nano-Liquid Chromatography using a Composite Carbon Nanotubes- Lauryl Polymethacrylate Capillary Monolithic Column
Authors: Aqel Ahmad , Alzahrani Soad S. , Al-Rifai Asma’a , Alturkey Mohammed , Yusuf Kareem , ALOthman Zeid A. , Badjah-Hadj-Ahmed Ahmed-Yacine
Published: June 2018

Background:

This work reports a green analytical method for the determination of organic
environmental pollutants using nano-liquid chromatography with a self-made column for rapid, sensitive,
inexpensive and efficient analysis of BTX pollutants in water. The applications of monolithic nanoscale
columns for quantitative analysis of environmental real samples are very limited in the literature.

Methods:

A capillary column containing a composite of multi-walled carbon nanotubes incorporated
into a lauryl methacrylate-co-ethylene dimethacrylate porous monolithic polymer was fabricated for
the determination of BTX pollutants in real water samples.

Results:

Baseline separation was accomplished at 0.4 µL/min flow rate with UV-detection set at 208
nm. Under the optimum conditions, the calibration curves were validated over the range of 1.0-500
µg/L with R2 more than 0.9992. The detection limits of benzene, toluene, o-xylene and m/p-xylene
were 0.25, 0.05, 0.075 and 0.05 µg/L, respectively. After a simple extraction process with a theoretical
preconcentration factor equal to 200, the recovery values in Milli-Q, tap and sea water samples were
found to be ranged from 84.85 to 97.84% with %RSD less than 7.5. Furthermore, we reported a comparison
between our prepared composite column with a commercial C18 silica based column which is
the most used in such analytical field. Each column demonstrated its advantages from different analytical
aspects.

Conclusion:

The application of monolithic columns and nano-scale LC for routine analysis of environmental
samples is very promising as the use of monolithic capillary columns offers several advantages
over conventional scale particulate packed columns.
Green Dispersive Micro Solid-Phase Extraction using Multiwalled Carbon Nanotubes for Preconcentration and Determination of Cadmium and Lead in Food, Water, and Tobacco Samples
Authors: Gouda Ayman A. , Amin Ali H. , Ali Ibrahim S. , Al Malah Zakia
Published: June 2018

Background:

Cadmium (Cd2+) and lead (Pb2+) have acute and chronic effects on humans
and other living organisms. In the present work, new, green and accurate dispersive micro solid-phase
extraction (DμSPE) method for the separation and preconcentration of trace amounts of cadmium
(Cd2+) and lead (Pb2+) ions in various food, water and tobacco samples collected from Saudi Arabia
prior to its Flame Atomic Absorption Spectrometric (FAAS) determinations was developed.

Methods:

The proposed method was based on a combination of oxidized multiwalled carbon
nanotubes (O-MWCNTs) with a new chelating agent 5-benzyl-4-[4-methoxybenzylideneamino)-4H-
1,2,4-triazole-3-thiol (BMBATT) to enrich and separate trace levels of Cd2+ and Pb2+. The effect of
separation parameters was investigated. The validation of the proposed preconcentration procedure
was performed using certified reference materials.

Results:

Analyte recovery values ranged from 95-102%, indicating that the method is highly accurate.
Furthermore, precision was demonstrated by the relative standard deviation (RSD < 3.0%). The limits
of detection were 0.08 and 0.1 μg L−1 for Cd2+ and Pb2+ ions, respectively. The preconcentration factor
was 200.

Conclusion:

The proposed method was used for the estimation of Cd2+ and Pb2+ ion content in various
real samples, and satisfactory results were obtained. The proposed method has high adsorption
capacity, rapid adsorption equilibrium, extremely low LODs, high preconcentration factors and
shortens the time of sample preparation in comparison to classical SPE.