bluuebunny/crossref_metadata_2025 huggingface dataset:
Interpretation Threshold Values for the Oxford Hip Score in Patients Undergoing Total Hip Arthroplasty
Authors: Harris Lasse K. , Troelsen Anders , Terluin Berend , Gromov Kirill , Overgaard Søren , Price Andrew , Ingelsrud Lina H.
Published: March 2023

Background:

Patient-reported outcome measures such as the Oxford Hip Score (OHS) can capture patient-centered perspectives on outcomes after total hip arthroplasty (THA). The OHS assesses hip pain and functional limitations, but defining interpretation threshold values for the OHS is warranted so that numerical OHS values can be translated into whether patients have experienced clinically meaningful changes. Therefore, we determined the minimal important change (MIC), patient acceptable symptom state (PASS), and treatment failure (TF) threshold values for the OHS at 12 and 24-month follow-up in patients undergoing THA.

Methods:

This cohort study used data from patients undergoing THA at 1 public hospital between July 2016 and April 2021. At 12 and 24 months postoperatively, patients provided responses for the OHS and for 3 anchor questions about whether they had experienced changes in hip pain and function, whether they considered their symptom state to be satisfactory, and if it was not satisfactory, whether they considered the treatment to have failed. The anchor-based adjusted predictive modeling method was used to determine interpretation threshold values. Baseline dependency was evaluated using a new item-split method. Nonparametric bootstrapping was used to determine 95% confidence intervals (CIs).

Results:

Complete data were obtained for 706 (69%) of 1,027 and 728 (66%) of 1,101 patients at 12 and 24 months postoperatively, respectively. These patients had a median age of 70 years, and 55% to 56% were female. Adjusted OHS MIC values were 6.3 (CI, 4.6 to 8.1) and 5.2 (CI, 3.6 to 6.7), adjusted OHS PASS values were 30.6 (CI, 29.0 to 32.2) and 30.5 (CI, 29.3 to 31.8), and adjusted OHS TF values were 25.5 (CI, 22.9 to 27.7) and 27.0 (CI, 25.2 to 28.8) at 12 and 24 months postoperatively, respectively. MIC values were 5.4 (CI, 2.1 to 9.1) and 5.0 (CI, 1.9 to 8.7) higher at 12 and 24 months, respectively, in patients with a more severe preoperative state.

Conclusions:

The established interpretation threshold values advance the interpretation and clinical use of the OHS, and may prove especially beneficial for registry-based evaluations of treatment quality.

Level of Evidence:

Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Belle Infidèle
Authors: García Martínez Aurora María
Published: March 2023

Constant d’Hermenches, Benjamin Constant, Charles-Emmanuel de Charrière, Camille et Pierre Malarmey ont tous un point en commun, une femme: Isabelle de Charrière. Ces hommes, entre autres, parsemèrent le chemin de Belle et jouèrent un rôle important dans sa vie monotone. Par les documents reccueillis dans cet article, il nous sera possible de savoir si ce rôle se limita à une innocente amitié ou alors, traversa les frontières de la décence faisant de Belle une infidèle.

Constant d’Hermenches, Benjamin Constant, Charles-Emmanuel de Charrière, Camille y Pierre Malarmey tienen todos un punto en común, una mujer: Isabelle de Charrière. Estos hombres, entre otros, se cruzaron en el camino de Belle y jugaron un papel importante en su monótona vida. Los documentos recopilados en este artículo nos permitirán averiguar si dicho papel solo fue una inocente amistad o traspasó las fronteras del decoro haciendo de Belle una infiel.
Reseñas
Authors: Luque González José Antonio
Published: March 2023

Reseña bibliográfica
Terminología vitivinícola del Dictionnaire Général des Termes propes à l'agriculture de Louis Liger
Authors: Álvarez Jurado Manuela
Published: March 2023

Es innegable el interés lexicográfico que surge a partir del siglo XVIII a través de la publicación de obras de carácter especializado que trataban los diferentes ámbitos de la ciencia o la tecnología. Muchas de estas obras se centraron en el estudio de la agricultura en general y otras en diferentes cultivos en particular. Sin embargo hay que esperar al siglo XVIII para asistir a un auténtico progreso tecnológico aplicado a la agricultura lo que dio lugar a una serie de publicaciones especializadas así como a textos divulgativos a través de los cuales se logra un aumento considerable de la calidad de los cultivos. Los primeros diccionarios de agricultura aparecen en Francia entre los años 1660 y 1750 y a través de ellos se pretende difundir la nueva terminología agrícola ligada a los recientes avances y hacerlos llegar a un público cada vez más amplio. Esta divulgación científica no sólo utilizó como canal de difusión los diccionarios sino que además se publicaron numerosos tratados enciclopédicos y manuales especializados. Con este trabajo se presenta un corpus terminológico sobre viticultura representativo de los numerosos y diferentes corpus que se llevaron a cabo en el siglo XVIII Para la elaboración de este corpus hemos realizado una extracción de la de terminología del vino presente en un diccionario de principios del siglo XVIII sobre agricultura, el Dictionnaire général des termes propres à l’agriculture, publicado por Louis Liger en 1703. Aunque en numerosas ocasiones se ha quitado valor a este Diccionario consideramos que es innegable su relevancia ya que, según hemos podido comprobar y como trataremos de demostrar a lo largo del trabajo, la mayor parte de estos términos seleccionados junto a sus definiciones, aparecen en otros diccionarios de la época lo que demuestra que la obra de Liger tuvo gran aceptación no sólo entre el público sino también entre los autores de diccionarios para quienes Liger se convirtió en un referente.
Trasvases culturales de la literatura al cine: el proyecto "Literaturverfilmung" (DE/FR-ES)
Authors: Balbuena Torezano María del Carmen
Published: March 2023

Es indudable la relación existente entre cine y literatura. Son numerosos los ejemplos de obras literarias llevadas al cine, algunas de ellas con un claro éxito de taquilla y galardones en festivales cinematográficos. La discusión entre la jerarquía entre Literatura y Séptimo Arte, aún no terminada, pone de manifiesto la posibilidad de representar de dos formas distintas una misma realidad estética. Pero la recepción del arte, ya sea en un medio u otro, está indudablemente condicionada por los medios y las condiciones en las cuales texto literario y texto fílmico se gestan. Amén de la versión original en la que se crea la obra cinematográfica, entra en juego un tercer factor decisivo para la recepción de la obra fílmica, y, con ello, también en parte de la obra literaria: la traducción audiovisual del producto cinematográfico, ya sea mediante el subtitulado, ya sea mediante el doblaje. En esta traducción cobra una especial relevancia el trasvase de los elementos culturales, pues en buena medida sólo mediante una correcta presentación de éstos en la pantalla, y también en los diálogos y el propio guión, el espectador recibirá en la lengua meta aquellos otros elementos culturales presentes en la obra literaria, génesis en algunos casos, y modelo en otro, de la cinematográfica.
Un autor olvidado de relatos históricos: Paul Lacroix "Le Bibliophile Jacob"
Authors: García Calderón Ángeles
Published: March 2023

Trabajo que trata de rescatar del olvido a un humanista francés del XIX, persona de gran influencia en su época, más conocido por su pseudónimo (“le Bibliophile Jacob”) que por su nombre (Paul Lacroix), cuya figura tendría una gran influencia en la atmósfera cultural de la capital parisina, desde su posición de conservador de la importante “Bibliothèque de l’Arsenal” hasta su labor de escritor-periodista, pasando por su afición a la narración histórica, en una época en la que toda Europa sentía la influencia del creador de la novela histórica Walter Scott. Preceden a la figura de Lacroix dos breves apartados sobre el relato histórico y su desarrollo en Francia.
LA PROGRAMACIÓN DE CONTENIDOS EN LAS GUÍAS DOCENTES DE TROMPETA DE LOS CONSERVATORIOS SUPERIORES DE ANDALUCÍA
Authors: Rodríguez Azorín Jesús
Published: March 2023

El presente artículo realiza un estudio comparativo de los contenidos programados en las Guías Docentes de los cinco conservatorios superiores andaluces, que pueda servir de reflexión para la ampliación y mejora de los materiales didácticos empleados en la programación de la asignatura.
CONSERVATORIO SUPERIOR DE MÚSICA "RAFAEL OROZCO". MEMORIA DEL CURSO 2004-2005.
Authors: Romero Aljama Francisco José
Published: March 2023

Actos musicales celebrados en el Conservatorio Superior de Música Rafael Orozco de Córdoba durante el curso académico 2004-2005.
EL AMOR BRUJO A TRAVÉS DE LA CRÍTICA MUSICAL
Authors: Barbero Consuegra Gabriel , Barbero Consuegra David
Published: March 2023

El Amor Brujo es propuesto a Falla por Gregorio Martínez Sierra. Se tenía la idea de un texto cantado, con la inclusión de algunos fragmentos de danza. Para gran parte de los críticos de la época, El Amor Brujo era una obra de difícil calificación.
MÚSICA Y PERSPECTIVA HISTÓRICA.
Authors: Prados Sillero Oscar
Published: March 2023

Hoy en día, la música del pasado se pone relación con su propio sistema de referencia estético y, en función de ese contraste, se la valora. Las cualidades estéticas de la música procedentes de las características de ésta en lo relativo al tiempo y las circunstancias de composición eran muy diferentes a comienzos del siglo XIX de como lo son actualmente. Perspectiva histórica es por tanto un concepto fundamental.
SCHÖNBERG Y STRAVINSKI: EN LAS CIMAS DE LA DESESPERACIÓN.
Authors: Millán Julián
Published: March 2023

Los contrastes binarios subyacen en todas las sociedades, y Stravinski y Schönberg, personajes pintorescos, tuvieron su protagonismo.
The justification of morality and the justification of utilitarianism in Jeremy Bentham’s ethics
Authors:   Institute of Philosophy, Russian Academy of Sciences (Russia), Prokofyev Andrey V.
Published: March 2023

The paper deals with the correlation between the justification of morality and the justifi­cation of utilitarian normative ethics in the two treatises of Jeremy Bentham: An Intro­duction to the Principles of Morals and Legislation and Deontology. In the Introduction, the general requirement of morality (‘promote the good of others’) is considered justified because a) it is integrated into the structure of the principle of utility and only contingent to the concurring principles (the principle of asceticism and the principle of sympathy and antipathy), b) the two concurring principles cannot withstand rational criticism, c) the list of principles is closed. There are two additional strategies to justify morality in the treatise. Bentham claims that the advantages of having a reputation of a trustworthy person are a sufficient reason to hold burdensome obligations. At the same time, he in­sists that an agent cannot persuade other people that her moral judgments are right unless these jugments are grounded in her recognition of the equal non-instrumental value of ev­ery person. In the Deontology, Bentham expands on the second strategy – the identifica­tion of moral virtue (duty) with the correctly understood personal interest of an agent. First, he proposes such a conception of moral virtue (duty) where sacrifices and efforts made by a person of prudence, probity, and beneficence are interpreted as the result of a clash among her own interests. Then, he demonstrates that the system of sanctions (sympathetic, religious, physical, moral, political) peculiar to human societies makes ad­vantages brought by breaches of prudence, probity, and beneficence illusory.
Deep Learning-Based Multiresolution Parameterization for Spatially Adaptive Model Updating
Authors: Valiyev Mahammad , Mohd Razak Syamil , Jafarpour Behnam
Published: March 2023

This paper presents a new deep learning-based parameterization approach for model calibration with two important properties: spatial adaptivity and multiresolution representation. The method aims to establish a spatially adaptive multiresolution latent space representation of subsurface property maps that enables local updates to property distributions at different scales. The deep learning model consists of a convolutional neural network architecture that learns successive mapping across multiple scales, from a coarse grid to increasingly finer grid representations. Once trained, the architecture learns latent spaces that encode spatial information across multiple scales. The resulting parameterization can facilitate the integration of data at different resolutions while enabling updates to the desired regions of the domain. Unlike the standard deep learning latent variables that are not localized and do not provide spatial adaptivity, the presented method enables local update capability that can be exploited to incorporate expert knowledge into assisted model updating workflows. Examples with two-dimensional multi-Gaussian random fields are used to introduce the method and its properties, followed by application of the method to a travel-time tomography inverse problem to investigate its model updating performance.
An 18F-FDG-PET/CT-based radiomics signature for estimating malignance probability of Solitary Pulmonary Nodule
Authors: Zheng Jingchi , Hao Yue , Guo Yan , Du Ming , Wang Pengyuan , Xin Jun
Published: March 2023

Background.
Some SPNs as early manifestations of lung cancer, it is difficult to determine its nature, which brings great trouble to clinical diagnosis and treatment. Radiomics can deeply explore the essence of images and provide clinical decision support for clinicians. The purpose of our study was to explore the effect of positron emission tomography (PET) with 2-deoxy-2-[fluorine-18] fluoro-D-glucose integrated with computed tomography (CT; 18F-FDG-PET/CT) combined with radiomics for predicting probability of malignancy of solitary pulmonary nodules (SPNs).
Methods.
We retrospectively enrolled 190 patients with SPNs confirmed by pathology from January 2013 to December 2019 in our hospital. SPNs were benign in 69 patients and malignant in 121 patients. Patients were randomly divided into a training or testing group at a ratio of 7:3. Three-dimensional regions of interest (ROIs) were manually outlined on PET and CT images, and radiomics features were extracted. Synthetic minority oversampling technique (SMOTE) method was used to balance benign and malignant samples to a ratio of 1:1. In the training group, least absolute shrinkage and selection operator (LASSO) regression analyses and Spearman correlation analyses were used to select the strongest radiomics features. Three models including PET model, CT model, and joint model were constructed using multivariate logistic regression analysis. Receiver operating characteristic (ROC) curves, calibration curves, and decision curves were plotted to evaluate diagnostic efficiency, calibration degree, and clinical usefulness of all models in training and testing groups.
Results.
The estimative effectiveness of the joint model was superior to the CT or PET model alone in the training and testing groups. For the joint model, CT model, and PET model, area under the ROC curve was 0.929, 0.819, 0.833 in the training group, and 0.844, 0.759, 0.748 in the testing group, respectively. Calibration and decision curves showed good fit and clinical usefulness for the joint model in both training and testing groups.
Conclusion.
Radiomics models constructed by combining PET and CT radiomics features are valuable for distinguishing benign and malignant SPNs. The combined effect is superior to qualitative diagnoses with CT or PET radiomics models alone.
Long-acting recombinant neuritin with increased stability
Authors: Meng Pingping , Liang Mengjie , Wei Yu , Yuan Wumei , Zhu Liyan , Zhu Jingling , Sun Jiawei , Huang Jin
Published: March 2023

Objective: To obtain the long-acting protein neuritin we fused the carboxyl-terminal peptide (CTP) to the C-terminal of neuritin and expressed it in Chinese hamster ovarian (CHO) cells.
Methods：The plasmid was constructed by fusion PCR. Affinity chromatography is used for protein purification. Thermal stability and serum stability were used to evaluate protein stability.
Results: The molecular weight of the neuritin-CTP was determined to be approximately 20 kDa. Subsequent functional analysis showed that the purified neuritin-CTP promoted neurite outgrowth in PC12 cells at a rate equivalent to that observed with neuritin. The stability experiments showed that the degradation rate of neuritin was 100% after incubation at 37°C for 72 h, whereas only approximately 20% of the neuritin-CTP was degraded under the same conditions. Similarly, the serum stability analysis results showed that neuritin degraded by approximately 90% and neuritin-CTP degraded by approximately 30% after incubation at 37°C for 72 h.
Conclusions: Fusion with CTP can effectively increase the stability of neuritin without affecting its secretion and activity. These results provide a basis for the construction of long-acting neuritin proteins.
Determining the Characteristics of a Healthy Environment Promoting the Health of Women Working in the Hospital: A Qualitative Study
Authors: Faghihi Mitra , Farshad Ali Asghar , Salehi Nasim , Whitehead Dean , Ghayen Masoud Motalebi , Izadi Bahar , Mansourian Morteza
Published: March 2023

Background and Purpose: The workplace is one of the priorities for health promotion in the 21st century by extending as the adult population extends. Also, the work environment has a significant impact on people's health. Therefore, the aim of this study was to determine the characteristics of a healthy environment promoting the health of women working in the hospital.
Materials & Methods: This study was conducted using a qualitative method and content analysis. The participants were selected using the purposive sampling total of 48 working women, hospital managers, and health promotion specialists participated in the study. In this study, we tried to select participants with maximum diversity in terms of age, work experience, and the sector they are working in. The data were collected using a semi-structured interview. The texts of the interviews were extracted and divided into the meaningful units. The criterion of credibility or acceptability of the data (Credibility) was used to ensure the accuracy of the study results.
Results: In the process of data analysis, 31 basic concepts that had the same characteristics were grouped into 12 subcategories, and based on the common characteristics at a more abstract level: they were transformed into 3 main categories, including organizational management and commitment to the health of working women. The psychological environment supports women's health, and also the social environment promotes women's health in the hospital by providing services.
Discussion and conclusion: Hospital managers play an important role in creating healthy workplaces for women, and to achieve this goal, they should try to improve their health from the aspects of mental and social health and provide special services to working women.
Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19: a systematic review and meta-analysis
Authors: Sun Jing , Wang Shufang , Ma Xin , Wei Qingqing , Peng Yujuan , Bai Ying , Miao Guobin , Meng Chang , Liu Peng
Published: March 2023

Several clinical trials have evaluated the efficacy and safety of baricitinib in COVID-19 patients. Recently, there have been reports on critical patients, which are different from previous research results. Studies were searched in PubMed, Embase, and Cochrane Library databases on January 31, 2023. We performed a meta-analysis to estimate the efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19. This study is registered with INPLASY , number 202310086. A total of 3010 patients were included in our analyses. All included studies were randomized controlled trials or prospective study. There was no difference in 14-day mortality between the two groups (OR 0.23 [95% CI 0.03–1.84], I²=72%, P=0.17). In subgroup analyses we found that baricitinib did not seem to improve significantly in 24-day mortality critically ill patients (OR 0.60 [95% CI 0.35–1.02], I²=0%, P=0.06). Fortunately, baricitinib have led to faster recovery and shorter hospital stays for COVID-19 patients. There were no difference in infections and infestations, major adverse cardiovascular events, deep vein thrombosis and pulmonary embolism. Baricitinib is safe. At the same time, we can find that it reduces the mortality of COVID-19 patients, but the prognosis of the critically ill patients is not significantly improved.
A statistical method for quantifying progenitor population reveals incipient cell fate commitments
Authors: He Xionglei , Deng Shanjun , Gong Han , Zhang Di , Zhang Mengdong
Published: March 2023

Quantifying the number of progenitor cells that founder an organ, tissue or cell population is of fundamental value for understanding the development and homeostasis of a multicellular organism. Previous efforts rely on marker genes that are specifically expressed in progenitors. The strategy is, however, often hindered by the lack of ideal markers. By exploring the cell phylogenetic tree that records the cell division history during development, we here describe a general statistical method able to quantify the progenitors of any tissues or cell populations defined in an organism without progenitor-specific markers. The method, termed targeting coalescent analysis (TCA), computes for all cells of tissue the average coalescent rate at the monophyletic clades of the target tissue, the inverse of which then measures the progenitor number of the tissue. Both theoretical deduction and computer simulations supported the underlying logics of TCA, which was then validated by empirical data of nematode, fruit fly and mouse, all with required cell phylogenetic trees. We further showed that TCA can be used to identify lineage-specific gene expression upregulations during embryogenesis, revealing incipient cell fate commitments in mouse embryos.
Modeling Electrochemical Oxide Film Growth – Passive and Transpassive Behavior of Iron Electrodes
Authors: Bösing Ingmar
Published: March 2023

The phenomenon of passivity is crucial for many areas of our technological and metal-based civilization. Nevertheless, the mechanisms leading to passivity are still under investigation and not fully understood. Modeling passive film growth can bring insights into these processes which are experimentally hard or impossible to access. Therefore, this paper presents a comprehensive model which describes oxide film growth and dissolution under an external potential by interfacial reactions and transport of defects and electrons and holes. The simulation gives insights into the defect con-centrations and electric field during passive film growth and film dissolution and delivers an anodic transpassive dissolution mechanism.
An adaptive method to recover high dynamic range images from multi-camera systems in back-lighting scenario
Authors: Abedi Firas , Yang You , Liu Qiong
Published: March 2023

The reconstruction of multi-view high dynamic range images faces several challenges, including holes and artifact in the disparity map in non-linear and large baseline between the involved cameras. Furthermore, these challenges increased when a back-lighting scenario is involved, with the currently industrial growth. To dispense the disparity map estimation and it’s related challenges, and generate backlighting multi-view high dynamic range images, we propose a method that relays on accurately detected and matched features between the adjustment viewpoints instead of the estimation of the disparity map, thus providing a flexibility on the camera baseline. Next, we estimate exposure gain between the matched features. After that, we restore the multi-view low dynamic range images based on the estimated gain, and generate a final high dynamic range image per view. Experimental results demonstrate superior performance for the proposed method over state-of-the-art methods in both objective and subject comparisons. These results suggest that our method is suitable to improve the visual quality of multi-view low dynamic range images captured in low back-lighting conditions via commercial cameras sparsely located among each other in any general public infrastructure.
Highly Accurate Trimesh and PointNet based algorithm for Gesture and Hindi air writing recognition
Authors: Sharma Jayash Kumar , Gupta Rajeev , Sharma Shakti , Pathak Vinay , Sharma Manoj
Published: March 2023

Air writing and gesture recognition has been one of the most comprehensive and intensively researched areas due to their wide variety of applications in several domains of Human-Computer Interaction (HCI),such as gaming, medicines, and automobiles. This article presents ahighly accurate point-based algorithm for identifying dynamic air writing and free hand gesture recognition for Devanagari Hindi characters.Usually, the written gestures are limited in nature. In order to create a training data set, we are using Leap Motion Controller (LMC) that generates twenty-four sample points from the gesture drawn. In the pre-processing stage, a trimesh is generated using these sample points; the developed trimesh is then fed as input to PointNet. The algorithm developed measures the similarity of the drawn gesture with the training samples to identify and recognize the gesture drawn using Mahalanobis distance. The validation test indicates that the approach is quite accurate, giving a recognition rate of more than 97%. Comparative studies also show that the methodology performs better when trimesh is used as input for the PointNet and more training samples are used.
Cerebral Venous Sinus Thrombosis After a Third Dose of mRNA COVID-19 Vaccine in an Adolescent: A case report
Authors: Mizuno Shinsuke , Koyama Junji , Horikawa Shogo , Kishimoto Kenji , Hasegawa Daiichiro , Kosaka Yoshiyuki , Kasai Masashi
Published: March 2023

Background: Several effective vaccines against Coronavirus disease 2019 (COVID-19) have been developed to control the spread of the disease. A few cases of thrombosis have been reported post-vaccination, especially among young adult women immunized with viral vector-based vaccines; although pediatric cases of cerebral venous sinus thrombosis (CVST) have been rarely reported after messenger ribonucleic acid (mRNA) vaccine administration.
Case presentation: Here, we report a case of CVST in a 14-year-old girl immunized with the BNT16B2b2 vaccine. Other than this recent COVID-19 vaccination, there were no precipitant risk factors in her medical history. Laboratory work-up showed low levels of protein S activity. Further research revealed no pathological gene mutation. She was treated with anticoagulant therapy and discharged with mildly impaired coordination/movement of the fingers.
Conclusion: CVST may occur following a mRNA COVID-19 vaccination, even among children. Further investigations are needed to establish whether thrombotic events are merely incidental or are a complication associated with mRNA-based vaccines.
Toward Building an Open domain Hindi Dialogue System: A Study on Sequence-to-Sequence Architectures
Authors: Rana Sandeep Kumar , Singh Thoudam Doren
Published: March 2023

Open domain conversation systems have gained popularity in recent years due to their versatility and scalability, making them great virtual companions in dialog exchange. Artificial intelligence-based approaches are preferred over rule-based methods as they enable continuous growth and learning, making them increasingly becoming the preferred choice for many applications. However, creating chatbots for Hindi language presents a unique challenge due to the lack of publicly accessible benchmark datasets. To overcome this, a new dataset is derived by translating the Daily Dialog dataset into Hindi using AI4Bharat's IndicTrans model. Various sequence-to-sequence architectures are then trained and evaluated using this dataset to build a dialogue system for Hindi language. The analysis demonstrated that the sequence-to-sequence model with RNN-Gated Recurrent Unit (GRU)+Temporal Convolutional Network(TCN)+ Attention performed the best with an F1 score of 26.31. This study offers a new dataset for Hindi open-domain dialogue systems and sheds light on the performance of various sequence-to-sequence architectures on the dataset. This approach can be beneficial for creating open-domain dialogue systems for other under-resourced languages as well.
Fractal geometry of coronary plaque images within optical coherence tomography: A novel approach of plaque vulnerability in patients with acute coronary syndrome versus stable angina pectoris
Authors: Morikawa Tomoyuki , Hiro Takafumi , Mineki Takashi , Kojima Keisuke , Kogo Takaaki , Iida Korehito , Akutsu Naotaka , Murata Nobuhiro , Sudo Mitsumasa , Kitano Daisuke , Fukamachi Daisuke , Okumura Yasuo
Published: March 2023

Background and Purposes:
The main cause of acute coronary syndrome (ACS) is plaque rupture and thrombus formation. However, it has not been fairly successful to identify vulnerable plaque to rupture using conventional parameters of intravascular imaging modalities. Fractal analysis is one of the mathematical models to examine geometrical features of picture image using a specific parameter called as fractal dimension (FD) which suggests geometric complexity of the image. This study examined FD of the optical coherence tomography (OCT)-derived images of the culprit plaque in patients with ACS versus stable angina pectoris (SAP) in order to evaluate the feasibility of FD for identifying vulnerable coronary plaques, because coronary plaques in ACS patients are known to be more vulnerable than those in patients with SAP.
Methods and Results
We examined 65 cases (34 ACS patients, 31 SAP patients) in which the culprit lesion was imaged by OCT before percutaneous coronary intervention in patients with ACS and SAP. The culprit plaque lesion in the ACS group had a significantly larger mean lipid arc (203.8 ± 39.4° vs 152.3 ± 34.5°, p < 0.001) and a larger lipid plaque length (12.6 ± 5.1mm vs 7.7 ± 2.7mm, p < 0.001) and a thinner fibrous cap thickness (75.3 ± 22.3 µm vs 134.8 ± 53.2 µm, p < 0.001) than those in the SAP group. The prevalence of OCT -derived macrophage infiltration (MφI) in the entire culprit coronary vessel as well as that of the OCT-derived thin-cap fibroatheroma (TCFA) at the culprit lesion were significantly greater in the ACS group than those in the SAP group, respectively (MφI: 61.8% vs 35.5%, p = 0.048; TCFA: 44.1% vs 6.4%, p < 0.001). The FD of culprit plaque in the ACS group was significantly greater than in the SAP group (2.401 ± 0.073 vs 2.341 ± 0.051, p < 0.001). In multivariate regression analysis, the presence of MφI was a significant determinant of FD (regression coefficient estimate 0.049, CI: 0.018–0.079, p = 0.002).
Conclusions
The FD of OCT-derived image of culprit coronary plaque in the ACS group was significantly greater than that in the SAP group, indicating that the culprit plaque in ACS were structurally more complex. Therefore, fractal analysis of coronary OCT images might be clinically useful for identifying vulnerable coronary plaques.
Authorship Attribution using Tf-Idf weight with Machine Learning Approaches
Authors: Mahor Urmila , Kumar Aarti
Published: March 2023

Authorship attribution means automatically determining the authorship of an unrecognize document based on a given sample of text. Authorship attribution has a long history and a wide range of applications. As digitalization is being increased Authorship attribution is playing a vital role in forensics, plagiarism detection, authorship dispute, and research fields. It is very helpful when two persons claim ownership of the same document written by him/her. Authorship attribution is a classification problem, although it uses the techniques of text classification for the text pre-processing despite that it is far different from the goal of text classification because it purely depends on the non-deterministic writing style of the author. The success of the author attribution task highly depends on the writing style characteristics of the authors. Several researchers proposed many different kinds of features such as linguistic, syntactic, semantic, and content-based features to identify the writing style of the authors and many of them have been used by different classifiers to classify the documents. In this paper, we applied tf-idf frequency with FW and sylometric features with support vector machines and parametric and nonparametric methods with supervised and unsupervised classification techniques in authorship attribution. We conducted various experiments with the English corpus gathered from PANCLEF'12. We performed experiments on different feature sets extracted from Corpus with different classifiers and combined these results to improve our success rates. We identified which classifiers give good results on which feature sets. According to experiments, the success rates dramatically change with different combinations of feature sets, however, the test among them are support vector classifier with a bag of words, and Gaussian with function words.
A case of lead helix winding tricuspid chordae tendineae
Authors: Liu Tengfei , Ding Chunhua
Published: March 2023

As left bundle branch pacing (LBBP) is more likely physiological pacing，which has emerged as a novel pacing strategy that uses the native conduction system to improve ventricular synchrony with stable pacing parameters. Operation process of the lead implanation was performed relatively complex, lack ofa standard operation may lead to serious consequences. Recently, we encountered a case of the lead helix was winding the tricuspid chordae. Radio frequency ablation effectively solved this problem without causing serious complications. It is an effective and reliable method to solve the problem of electrode winding chordae. This case provided more clinical experience in handing the operative complications.
Dynamical analysis and optimal harvesting policy of a prey-predator model with Holling type-III functional response
Authors: Kumar Ankit , Poonia Ashish
Published: March 2023

In this study, we propose and analyze a two-dimensional prey-predator model with the harvesting of both prey and predator. The species are harvested according to the catch-per-unit effort (CPUE) hypothesis. It is assumed that the predator is partially dependent upon the prey population and followed by Holling type-III functional response. Steady states of the system are obtained, and local and global stability analysis is performed to examine the long-term behavior of the system. We also examine the effect of harvesting on the dynamics of the system. It is noticed that for higher values of harvesting efforts, the prey population becomes extinct via a transcritical bifurcation. We derive an optimal harvesting policy and obtain the optimal steady state solution and optimal harvesting efforts using Pontryagin’s Maximum Principle. Lastly, some numerical illustrations are presented in support of our theoretical findings. For a chosen set of parameters, we obtain the threshold value of some parameters beyond which the harvesting of prey biomass must be stopped for the sustainable growth of the species.
Developing and Validating a Japanese Version of the Plymouth Sensory Imagery Questionnaire (Psi-Q)
Authors: Hitsuwari Jimpei , Nomura Michio
Published: March 2023

Mental imagery refers to the representation of stimuli that are not physically present and has long been a subject of interest in psychology. Despite this, most of the research on mental imagery has been limited to visual images, with other types of imagery, such as sound and smell, receiving limited attention. A possible reason for this is the lack of appropriate scales to measure vividness of multisensory imagery. The Plymouth Sensory Imagery Scale (Psi-Q) has been developed to address this issue and has been used in several studies to measure the vividness of seven imagery: vision, sound, smell, taste, touch, body, and feeling. In this study of 400 participants in Japan, the Psi-Q was translated and tested for reliability and validity. Results showed good internal reliability and retest reliability, moderate to high correlations with other measures of construct validity, including mindfulness, Big Five, and life satisfaction. Additionally, there is no significant difference in total Psi-Q scores between the Japanese and British samples, although some differences were found in individual sensory imagery abilities. The study provides valuable insights into multisensory mental imagery and it is expected that research dealing simultaneously with the responses of multisensory modalities will further accumulate.
Künstliche Intelligenz verändert das Verhältnis zu uns selbst
Authors: Tully Claus
Published: March 2023

Rezension zuHirsch-Kreinsen, Hartmut. 2023. Das Versprechen der künstlichen Intelligenz. Gesellschaftliche Dynamik einer Schlüsseltechnologie. Frankfurt / New York: Campus Verlag. 35,00 €Schulz, Peter. 2022. Kapitalistische Subjektivation. Das Subjekt des kybernetischen Kapitalismus zwischen Digitalisierung, Prekarisierung und Autoritarismus. Bielefeld: transcript. 44,99 €Fuchs, Christian. 2023. Der digitale Kapitalismus. Arbeit, Entfremdung und Ideologie im Informationszeitalter. Weinheim und Basel: Beltz Juventa. 35,00 €
HEPATITIS B, HEPATITIS C AND HIV AMONG DRUG USERS IN METHADONE MAINTENANCE TREATMENT: PREVALENCE, DOSES, TREATMENT COMPLIANCE
Authors:   Psychiatrist, Ar-Razi Psychiatric University Hospital, CHU Ibn Sina Rabat., Zaki Amal ,   Faculty of Medicine and Pharmacy of Rabat. Mohammed V University, Rabat., Sabir Maria ,   Professor of Psychiatry.,   Faculty of Medicine and Pharmacy of Rabat. Mohammed V University, Rabat., El Omari Fatima ,   Professor of Psychiatry.,   Faculty of Medicine and Pharmacy of Rabat. Mohammed V University, Rabat.
Published: March 2023

TheUsersofopioidsubstances,especiallyinjectingdrugs,areathighriskofinfection with blood- borne viruses,such as hepatitis B,C and human immunodeficiency virus, due to the sharing of needles and injection equipment. Methadone substitution treatment is approven device in the risk reduction strategy of hepatitis B,C and HIV infection.The aim of this studyis to determine: the socio-demographic and medical psychiatric characteristics of patients with hepatitis B,C and HIV under methadone,the prevalence of hepatitis C,B and HIV,the dose of methadone and compliance with treatment in this population. Materials and methods: This is a retrospective descriptive study of patients admitted to the center of addictology at the hospital Ar-razi of Sale in Morocco , specifically in methadone unit. Results: The prevalence of hepatitis C, B and HIV were respectively 80%, 13% and 4% in patients with positive serology, the average dose of methadone was higher than the dose of all patients enrolled in the methadone program. 80% of patients under methadone with positive serology to HCV, HBV and HIV had a polyconsumption of psychoactive substances (cannabis, cocaine, alcohol, benzodiazepine). 72% of our patients with hepatitis C received treatment for their infection while all the patients with HIV were put on antiretroviral drugs with good therapeutic compliance. Conclusion:Methadone substitution therapy has proven to be a successful strategy to reduce the risk of HIV, HCV and HBV infection in opioid-dependent patients. However, the adjustment of methadone doses and systematic screening for HIV, HCV and HBV is essential in this vulnerable population.
COMPARISION OF TWO DIFFERENT RADIO THERAPY FRACTIONATIONS FOR METASTATIC SPINAL CORD COMPRESSION
Authors:   M.B.B.S Post-Graduate of Radiation Oncology, Guntur Medical College Guntur, Guntur District., V. Lakshmikeerthana Gundavarapu , Revathi Jakkula ,   M.B.B.S Post-Graduate of Radiation Oncology, Guntur Medical College Guntur, Guntur District., Venkata Sudeeshna Araveeti ,   M.B.B.S Post-Graduate of Radiation Oncology, Guntur Medical College Guntur, Guntur District., Durga Prasad G. ,   Professor and HOD Radiotherapy Department, Guntur Medical College, Guntur, Guntur District.
Published: March 2023

Background: Indian population experiences most common cancers of Lung, Breast, prostate most commonly where the disease is systemic to start with, and a high chance of metastasis to bones. Our institute experience most common radiotherapy emergency of cord compression so regularly that we need to frame a protocol for this cases on priority and the linac machine time is also so precious. Objectives: To compare the overall response in patients treated with two different fractionation schedules of 4 Gy x 5 fractions versus 3 Gy x 10 fractions for metastatic spinal cord compression. Materials and Methods: It is a prospective comparative study with total number of patients enrolled in the study is 60. After obtaining informed consent, then patients were enrolled in the study. Patients with known biopsy proven tumour presenting with metastatic spinal cord compression causing lower limb motor dysfunction. Results: Results of the study showed that overall response to radiation and ambulatory status of patients post irradiation were similar in both arms. There was no significant difference between the arms. Conclusion: Comparatively no difference in over all response and ambulatory status of patient by different fractionation. In general patients with MSCC have a poor survival and short course fractionation with 4 Gy x 5 fractions can be considered instead of the standard 3 Gy x 10 fractions.
FOSFOMYCIN SUSCEPTIBILITY IN BACTERIAL ISOLATES FROM UROPATHOGENS WITH SPECIAL REFERENCE TO EXTENDED SPECTRUM B-LACTAMASE(ESBL) PRODUCERS AND MULTIDRUG RESISTANT(MDR) ORGANISMS
Authors:   Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Chinavutapalli, Gannavaram Mandal, Krishna district, A.P, 521286., BN Durgabhavani , M. Giridharkumar ,   Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Chinavutapalli, Gannavaram Mandal, Krishna district, A.P, 521286., MSS Pradeep ,   Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Chinavutapalli, Gannavaram Mandal, Krishna district, A.P, 521286., Vardhana Rao K. Vishnu ,   Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Chinavutapalli, Gannavaram Mandal, Krishna district, A.P, 521286.
Published: March 2023

Introduction: Urinary tract infection (UTI) is one of the most common clinical entities encountered by physicians globally. Most of the uropathogens exhibit Multiple Drug Resistance(MDR) mechanisms especially in the members of Enterobacteriaceae. As there is increase in resistance rates, there is necessity in opting alternative treatment Strategies in cases of UTI like Fosfomycin which seems to be a good option attracting the clinicians interest globally. Objective: To evaluate the Fosfomycin susceptibility in bacterial isolates from uropathogens. Methodology: A total of 624 urine samples were included in the study, out of which 84 isolates satisfying Kass concept were processed and identified by standard protocol and all the isolates were tested for Fosfomycin susceptibility by using Kirby Bauer disc diffusion and E-test, interpreted as per Clinical Laboratory Standards Institute(CLSI) guidelines. Results:Among the isolates majority were Escherichia coli(60.71%) followed by Klebsiella species(26.19%), Enterococcus species(8.33%), Staphylococcus saprophyticus(2.38%) and Proteus species(2.38%) out of which 54.76% were Extended-spectrum-beta-lactamase-producing(ESBL) organisms, 40.47% were Multi Drug Resistant Enterobacteriaceae(MDRE) and 15.47% were Carbapenem Resistant Organisms(CRO). Fosfomycin susceptibility was observed highest in Staphylococcus saprophyticus(100%), Proteus species(100%) followed by E.coli(96.7%) Klebsiella species(95.45%) and Enterococcus species(85.71%). Conclusion: Our study mainly focussed on Fosfomycin susceptibility in various uropathogens where Fosfomycin was found to have a promising role in treating UTI with both Gram positive and Gram negative organisms and can be considered as a drug of choice for empirical oral treatment in cases of UTI.
A MORPHOLOGICAL ODDITY IN MANDIBULAR LEFT SECOND PREMOLAR WITH TWO ROOTS: A CASE REPORT
Authors: Sundesha Manish , Choudhary Anita
Published: March 2023

Thorough knowledge of different root canal morphology with appropriate assessment of the pulp chamber floor and proper interpretation of radiographs are prerequisite for successful root canal therapy. The possibility of additional or extra root or canal should be considered even in teeth with a low frequency of abnormal root canal anatomy. This article reports on a case of mandibular second premolar with two roots which was successfully treated using endodontic therapy with adequate restoration.
A REVIEW ON CHRONIC MALE UTI AND ITS IMPACT ON MENTAL HEALTH
Authors:   Clinical Observer, Wrightington, Wigan and Leigh NHS Foundation Trust, Wigan, Greater Manchester, United Kingdom., Jaffar Azad Ajeeth Rehman Abdul
Published: March 2023

The most common bacterial infections in men are Urinary Tract Infections (UTI). 30-50% of men who get UTI will have a recurrence within 6-12 months despite receiving acute therapy. There are several organisms that can cause these, but Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis, and Staphylococcus saprophyticus are the most prevalent ones. Other conditions include prostatitis, epididymitis, orchitis, cystitis, and urethritis. Men are susceptible to this, and it frequently significantly lowers quality of life. The severity of the discomfort, urinary problems, and quality of life restrictions were some of the outcomes. The personal psychosocial effects of male UTI recurrence are the main topic of this review. This research offers a review of chronic male UTI and its impact on Mental health. This study also looks at the several psychosocial factors such as pain, severity, and urine sensations may influence their quality of life.