bluuebunny/crossref_metadata_2025 huggingface dataset:
PLAYA DYNAMICS AND SALINITY: A STUDY OF YELLOW LAKE ON THE HIGH PLAINS OF TEXAS
Authors: Stout John E.
Published: December 2022

Saline playas on the Southern High Plains are almost always located on large cattle ranches but they are of limited value to the herds of cattle grazing around their outer margins. Saline playas are often without water for extended periods and, after inundation, they experience considerable evaporative loss leading to hypersaline conditions. The primary goal of this study was to develop a quantitative method that combines the transitory nature of playa lakes and the variability of salinity into a set of parameters that can be used to compare playas or other surface water sources. Regarding water quality, a variable was developed that describes the fraction of observations with salinity levels below the salt tolerance threshold for cattle. With regard to water availability, water depth measurements were used to compute the fraction of time that a playa contains water. These two variables are combined to form a new variable that represents the fraction of time that water is both available and of acceptable quality. To demonstrate the utility of this method, data was collected at Yellow Lake, a large saline playa located on the Yellow House Ranch northwest of Lubbock, Texas. Results suggest that the playa contained water 50.8% of the time over a five-year period but the fraction of water samples with acceptable salinity was only 6.5%. The resulting fraction of time that water was both available and of acceptable quality was only 3.3%. This technique could be used to compare other ephemeral surface water sources in the region.
Learning invariant representation using synthetic imagery for object detection
Authors: Jiang Ning , Fang Jinglong , Shao Yanli
Published: December 2022

Recent years have witnessed a rapid advance in training and testing synthetic data through deep learning networks for the annotation of synthetic data that can be automatically marked. However, a domain discrepancy still exists between synthetic data and real data. In this paper, we address the domain discrepancy issue from three aspects: 1) We design a synthetic image generator with automatically labeled based on 3D scenes. 2) A novel adversarial domain adaptation model is proposed to learn robust intermediate representation free of distractors to improve the transfer performance. 3) We construct a distractor-invariant network and adopt the sample transferability strategy on global-local levels, respectively, to mitigate the cross-domain gap. Additional exploratory experiments demonstrate that the proposed model achieves large performance margins, which show significant advance over the other state-of-the-art models, performing a promotion of 10%–15% mAP on various domain adaptation scenarios.
Probabilistic double hierarchy linguistic MADM for location selection of new energy electric vehicle charging stations based on the MSM operators
Authors: Lei Fan , Cai Qiang , Wei Guiwu , Mo Zhiwen , Guo Yanfeng
Published: December 2022

The emergence of new energy electric vehicles (NEEV) can effectively reduce vehicle fuel consumption and alleviate the contradiction between fuel supply and demand. It has made great contributions to improving the atmospheric environment and promoting the development of environmental protection. However, the insufficient number of new energy electric vehicle charging stations (NEEVCSs) and unreasonable coverage areas have become obstacles to the large-scale promotion of new energy electric vehicles. Therefore, we build a multi-attribute decision making (MADM) model based on probabilistic double hierarchy linguistic weight Maclaurin symmetric mean (PDHLWMSM) operator and a MADM model based on probabilistic double hierarchy linguistic weight power Maclaurin symmetric mean (PDHLWPMSM) operator to select the best charging station construction point from multiple alternative sites. In addition, the model constructed in this paper is compared with the existing MADM models to verify the scientificity of the model proposed in this paper.
Sustainable development goals for gender equality: Extracting associations among the indicators of SDG 5 using numerical association rule mining
Authors: Saini Munish , Adebayo Sulaimon Oyeniyi , Singh Harnoor , Singh Harpreet , Sharma Suchita
Published: December 2022

The United Nations prescribed the Sustainable Development Goals (SDGs) to various nations to provide enduring answers to widespread problems and to give long-lasting solutions to common issues being faced across the globe. SDG 5 in particular was aimed at minimizing gender inequality by employing 9 targets and 14 indicators. The indicators serve as a yardstick to measure the progress of each of the 9 targets. This research takes an in-depth look at the perspectives of SDG 5 –Gender Inequalities, its targets, and indicators. Furthermore, explanatory data analysis and numerical association rule mining alongside QuantMiner are applied to the generated Indian datasets on SDG 5 to extract patterns and associations among the fourteen indicators of SDG 5. The association rule mining carried out on the indicators reveals the pattern of association among these indicators. Legal provision for women and the rate of crimes against women have a perfect association of 100% while the association between legal provision for women and women who have experienced physical violence stands at 80%. The full relationships of all the 14 indicators are discussed extensively in the result and discussion section. Overall, it is established that these indicators are interdependent. This will make it easier for academics, the general public, and governmental and non-governmental organizations to understand the trends and form informed opinions on issues relating to gender inequality and SDG 5.
Multi-objective route recommendation method based on Q-learning algorithm
Authors: Yu Qingying , Xiao Zhenxing , Yang Feng , Gong Shan , Shi Gege , Chen Chuanming
Published: December 2022

With the continuous expansion of city scale and the advancement of transportation technology, route recommendations have become an increasingly common concern in academic and engineering circles. Research on route recommendation technology can significantly satisfy the travel demands of residents and city operations, thereby promoting the construction of smart cities and the development of intelligent transportation. However, most current route recommendation methods focus on generating a route satisfying a single objective attribute and fail to comprehensively consider other types of objective attributes or user preferences to generate personalized recommendation routes. This study proposes a multi-objective route recommendation method based on the reinforcement learning algorithm Q-learning, that comprehensively considers multiple objective attributes, such as travel time, safety risk, and COVID-19 risk, and generates recommended routes that satisfy the requirements of different scenarios by combining user preferences. Simultaneously, to address the problem that the Q-learning algorithm has low iteration efficiency and easily falls into the local optimum, this study introduces the dynamic exploration factor σ and initializes the value function in the road network construction process. The experimental results show that, when compared to other traditional route recommendation algorithms, the recommended path generated by the proposed algorithm has a lower path cost, and based on its unique Q-value table search mechanism, the proposed algorithm can generate the recommended route almost in real time.
An effective ontology-based query response model for risk assessment in urban flood disaster management
Authors: Karthikeyan N. , Gugan I. , Kavitha M.S. , Karthik S.
Published: December 2022

The drastic advancements in the field of Information Technology make it possible to analyze, manage and handle large-scale environment data and spatial information acquired from diverse sources. Nevertheless, this process is a more challenging task where the data accessibility has been performed in an unstructured, varied, and incomplete manner. The appropriate extraction of information from diverse data sources is crucial for evaluating natural disaster management. Therefore, an effective framework is required to acquire essential information in a structured and accessible manner. This research concentrates on modeling an efficient ontology-based evaluation framework to facilitate the queries based on the flood disaster location. It offers a reasoning framework with spatial and feature patterns to respond to the generated query. To be specific, the data is acquired from the urban flood disaster environmental condition to perform data analysis hierarchically and semantically. Finally, data evaluation can be accomplished by data visualization and correlation patterns to respond to higher-level queries. The proposed ontology-based evaluation framework has been simulated using the MATLAB environment. The result exposes that the proposed framework obtains superior significance over the existing frameworks with a lesser average query response time of 7 seconds.
M-fuzzifying convex quasi-uniform spaces
Authors: Wu Xiu-Yun , Niu Yu-Jie , Zhang Hui-Min
Published: December 2022

In this paper, the notion of M-fuzzifying convex remotehood systems is introduced and characterizations of M-fuzzifying convex spaces are obtained. Further, notions of remote mappings and M-fuzzifying convex quasi-uniformities are introduced. It is proved that M-fuzzifying convex quasi-uniform space and M-fuzzifying convex space are mutually induced. In order to discuss categorical relationships among M-fuzzifying convex quasi-uniform spaces, M-fuzzifying convex remotehood spaces and M-fuzzifying convex spaces, notions of M-fuzzifying quasi-uniformizable convex structures and M-fuzzifying quasi-uniformizable convex remotehood spaces are presented. It is proved that the category of M-fuzzifying quasi-uniformizable convex spaces and the category of M-fuzzifying quasi-uniformizable convex remotehood spaces can be embedded into the category of M-fuzzifying convex quasi-uniform spaces as subcategories.
An efficient wind measurement method with chaotic-sequence improved genetic-particle swarm optimization algorithm
Authors: Wang Encheng , Mao Zichen , Wang Jie , Lin Daming
Published: December 2022

Wind power is widely used in industry, meteorology, shipping and so on. Accurate measurement of wind parameters is the key to improve the efficiency of wind power application. But at present, wind parameters are largely measured by different devices based on time difference method, which is easily influnced by enviromental noise. Beam-forming algorithm can improve the ability to resist environmental noise and the accuracy of hardware itself. Therefore, the beam-forming algorithm can be used to measure wind parameters in the high noise environment. However, the efficiency of the algorithm depends on how to search for spectral peak. In this paper, a three-dimensional wind measurement method with chaotic-sequence improved genetic-particle swarm optimization algorithm is proposed to improve the waveform searching efficiency of beamforming algorithm. It first searches for rough target wind parameters globally, and then searches for precise target wind parameters locally. Through simulation verification, the proposed algorithm can measure the wind parameters after 0.087s under the condition of system error of 50dB and environmental noise of 20dB, the accuracy of wind speed is 0.5%, the accuracy of wind direction is 1%, and the accuracy of pitch angle is 0.5%. Compared with the wind measurement by traversal method, the proposed algorithm can improve the wind measurement efficiency by about 20 times, and has similar or even better measurement results.. And by comparing with other algorithms, the advantages of this algorithm are verified.
An intuitionistic dense fuzzy AHP-TOPSIS method for military robot selection
Authors: Swethaa S. , Felix A.
Published: December 2022

Land, marine and airborne are the three types of military robots used in the war-field. Land robots are the most crucially considered robots. Selecting a military land robot for a specific purpose is one of the challenging problems for a decision-maker to find the most preferred alternative when it involves fuzziness and uncertainty. Intangible factors are used while selecting the appropriate robotic system as it effectively deals with fuzziness. Intuitionistic dense fuzzy set, which is the combination of intuitionistic fuzzy set and dense fuzzy set, is capable of dealing with intangible factors. This study aims to design the integrated model on intuitionistic dense fuzzy AHP-TOPSIS to choose the most preferable military land robots under various circumstances. Robots for different types of situations, namely bomb disposal, search and rescue, surveillance and reconnaissance and war-fighter are considered. Moreover, the intuitionistic dense fuzzy AHP is utilized to calculate the subjective weights of the criteria and intuitionistic dense fuzzy TOPSIS is used to rank the alternatives. Further, a sensitivity analysis is examined to demonstrate the quality of the outcome and the results are compared with the fuzzy set, intuitionistic fuzzy set, and dense fuzzy set to show the efficiency of the proposed methodology.
The effectiveness of interventions to prevent intraventricular haemorrhage in premature infants: A systematic review and network meta-analysis
Authors: Yao Si Liang , Smit Elisa , Odd David
Published: December 2022

BACKGROUND: Intraventricular haemorrhage (IVH) is a common problem in preterm infants, being a major cause of morbidity and mortality. Despite many randomised controlled trials comparing interventions to prevent IVH, the best prevention remains unclear. This study aims to review all the interventions which intended to reduce the incidence of IVH and compare them in a network meta-analysis. METHODS: A search on MEDLINE, EMBASE, Emcare, and CENTRAL was performed. Randomised controlled trials which evaluated neonatal interventions with a primary aim to reduce incidence of IVH in preterm infants were eligible. A surface under a cumulative ranking curve (SUCRA) was produced to indicate the intervention’s likelihood of being the most effective for preventing IVH. RESULTS: 40 studies were eligible, enrolling over 6760 infants. Twelve intervention groups were found, including delayed cord clamping, erythropoietin, ethamsylate, fresh frozen plasma, heparin, ibuprofen, indomethacin, magnesium, nursing interventions, sedation, tranexamic acid, and vitamin E. Vitamin E and indomethacin had the highest probability of being the best interventions to prevent IVH in premature infants, but interpretation of these results is difficult due to study limitations. CONCLUSION: Despite the impact of IVH, we were unable to identify a clearly beneficial treatment to reduce its incidence. Interpretation of the network meta-analysis was limited due to differences within studied populations, wide range of therapies trialled, and underlying advances in neonatal care between units, and over time. Although vitamin E and indomethacin appear to be promising candidates, contemporaneous trials of these, or novel agents, enrolling the most at-risk infants is needed urgently.
Quantifying virtual self-motion sensations induced by galvanic vestibular stimulation
Authors: Gallagher M. , Romano F. , Bockisch C.J. , Ferrè E.R. , Bertolini G.
Published: December 2022

BACKGROUND: The vestibular system provides a comprehensive estimate of self-motion in 3D space. Widely used to artificially stimulate the vestibular system, binaural-bipolar square-wave Galvanic Vestibular Stimulation (GVS) elicits a virtual sensation of roll rotation. Postural responses to GVS have been clearly delineated, however quantifying the perceived virtual rotation vector has not been fully realised. OBJECTIVE: We aimed to quantify the perceived virtual roll rotation vector elicited by GVS using a psychophysical approach on a 3D turntable. METHODS: Participants were placed supine on the 3D turntable and rotated around the naso-occipital axis while supine and received square-wave binaural-bipolar GVS or sham stimulation. GVS amplitudes and intensities were systematically manipulated. The turntable motion profile consisted of a velocity step of 20°/s2 until the trial velocity between 0–20°/s was reached, followed by a 1°/s ramp until the end of the trial. In a psychophysical adaptive staircase procedure, we systematically varied the roll velocity to identify the exact velocity that cancelled the perceived roll sensation induced by GVS. RESULTS: Participants perceived a virtual roll rotation towards the cathode of approximately 2°/s velocity for 1 mA GVS and 6°/s velocity for 2.5 mA GVS. The observed values were stable across repetitions. CONCLUSIONS: Our results quantify for the first time the perceived virtual roll rotations induced by binaural-bipolar square-wave GVS. Importantly, estimates were based on perceptual judgements, in the absence of motor or postural responses and in a head orientation where the GVS-induced roll sensation did not interact with the perceived direction of gravity. This is an important step towards applications of GVS in different settings, including sensory substitution or Virtual Reality.
Incidence of peripheral vestibular disorders based on population data of South Korea
Authors: Jeong Junhui , Youk Tae Mi , Choi Hyun Seung
Published: December 2022

BACKGROUND: There have been no comprehensive studies on the incidence of peripheral vestibular disorders based on population-based data for a long-term period. OBJECTIVE: We investigated the incidence of peripheral vestibular disorders using population-based data representing the whole population of South Korea. METHODS: This study used the National Health Insurance Service data in Korea from 2008 to 2020. Peripheral vestibular disorders such as benign paroxysmal positional vertigo (BPPV), vestibular neuritis (VN), and Meniere’s disease (MD) were defined with diagnostic, treatment, or audiovestibular test codes. The annual incidence in total and according to sex, age, and residence was analyzed. RESULTS: The annual incidence of BPPV, VN, and MD per 100,000 was 51.4, 22.7, and 12.4 in 2008 and 181.1, 62.9, and 50.5 in 2020, respectively. The incidence of each was significantly different by sex (p < 0.001), age (p < 0.001), and residence (p < 0.001), with the highest value in female, people aged 60 years or older, and people who resided in metropolitan cities. CONCLUSIONS: The annual incidence of BPPV, VN, and MD had increasing trends from 2008 through 2020 in South Korea, and all were significantly higher in female, people aged 60 years or older, and people who resided in metropolitan cities.
Family physicians’ sick-listing practices in relation to mental disorders: A descriptive study
Authors: Drolet Lauriane , Caron Pier-Olivier , Forget Jacques , Turcotte Jean-Robert , Guimond Claude
Published: December 2022

BACKGROUND: Mental disorders are among the leading causes of disability for which family physicians are often required to complete sickness certificates. Yet, little is known about family physicians’ sick-listing practices in Quebec. OBJECTIVE: This study aims to describe their practices, difficulties and needs. METHODS: Twenty-three family physicians completed a comprehensive questionnaire on sickness certification practices. Descriptive statistics were used. RESULTS: Despite being completed on a weekly basis, sickness certifications were deemed problematic by all participants. While they rarely refused to sick-list a patient, 43.5% reported suggesting accommodations as an alternative to sick leave. Waiting-time to access psychotherapy and delays to set-up workplace accommodations are responsible for many unnecessary sick-leave prolongations. Lack of time, long duration absences, situations where the physician held a different opinion than the patient/healthcare provider and assessing an individual’s capacity to work are the most common reported problems. More than half of participants indicated medical schools do not greatly prepare them to carry out these tasks. CONCLUSION: Sickness certifications are deemed problematic, and more training might be key. Our results can be used by medical schools or bodies responsible for continuous education to improve training.
Prevalence of laboratory-related musculoskeletal disorders among biomedical scientists
Authors: Alwahaibi Nasar , Al Sadairi Mallak , Al Abri Ibrahim , Al Rawahi Samira
Published: December 2022

BACKGROUND: Laboratory– related musculoskeletal disorders (LMSDs) are injuries resulting from working in the laboratory. Biomedical scientists (BMSs) play an important role in any health care system. However, they are at high risk of exposure to the LMSDs. OBJECTIVE: This study aimed to estimate the prevalence and the associated risk factors of LMSDs among this group of healthcare professionals. METHODS: We conducted a cross-sectional survey using the Nordic Musculoskeletal Questionnaire to estimate the prevalence of the LMSDs among the BMSs. BMSs with occupational or non-occupational accidents that affected their musculoskeletal system were excluded from the study. A Chi-square test was performed to measure the significant association between different risk factors (age, gender, weight, height, nationality, specialty, educational level, nature of the job, and the number of experience years) and the prevalence of the LMSDs among the BMSs. RESULTS: The study included 83 BMSs. Females represented 63.9% and 36.1% were in the age group of 35– 44. The overall prevalence of the LMSDs was 77.1%. The most prevalent LMSDs were neck, shoulders, and lower back with 50.6%, 49.4%, and 43.4%, respectively. A total of 65.57% of BMSs had irregular symptoms of LMSDs. CONCLUSION: The study found that the prevalence of LMSDs among the BMSs was high. Good practice and training in ergonomics may minimize the prevalence of LMSDs among the BMSs.
Effects of a mobile health intervention on activities of stress self-management for workers
Authors: Lee Young Joo
Published: December 2022

BACKGROUND: Mobile health interventions are being widely tried because of their attractive advantages. However, there is not enough evidence for its effectiveness. OBJECTIVE: This study aimed to evaluate the effects of mobile app-based stress management intervention (mSMI) on highly stressed workers. METHODS: A sample of 82 white-collar workers with elevated symptoms of perceived stress (Perceived Stress Scale-10≥22) were randomly assigned to the intervention or control group. The mSMI consisted of three modules: self-management including a work diary, counseling based on cognitive behavioral therapy and interventions focused on music, meditation, relaxation and image healings. Self-report data were collected at the baseline and post-intervention. Study outcomes analyzed perceived stress, anxiety, depression, and work engagement. Data were assessed using analysis of covariance with covariates. RESULTS: There was significantly reduced perceived stress from baseline to 6 weeks in mSMI (t = 5.788, p < 0.001) and control group (t = 3.184, p = 0.003). After adjusting for covariates, the between-group difference in the perceived stress was significantly different (F = 4.051, p = 0.048); however, the effect size was small. There was no significant intervention effect on anxiety, depression, and work engagement. The process evaluation indicated that most participants (85.3%) were satisfied with the intervention and their mental health benefited. CONCLUSION: This study found that mobile health intervention facilitated perceived stress management for highly stressed workers. Further studies should address job-related outcomes and mental health symptoms in workers by applying the latest information technology and addressing the limitations of mobile interventions.
Managers’ and employees’ experiences of how managers’ wellbeing impacts their leadership behaviours in Swedish small businesses
Authors: Ahmadi Elena , Lundqvist Daniel , Bergström Gunnar , Macassa Gloria
Published: December 2022

BACKGROUND: There is a growing interest in managers’ wellbeing due to the observed associations between their wellbeing and leadership behaviours, and between leadership behaviours and employees’ wellbeing. However, it is still unclear how managers’ wellbeing influences their practiced leadership across different workplace contexts, which specific behaviours are affected, and how this varies across time. OBJECTIVE: The purpose of this study was therefore to explore managers’ and employees’ experiences and perceptions regarding the consequences of managers’ wellbeing for their leadership behaviours in small businesses. METHODS: Semi-structured interviews were conducted with 39 participants (20 managers and 19 employees) working at 12 Swedish small firms, and analysed using content analysis. RESULTS: The findings show that managers were more constructive when they felt well, and more passively destructive when unwell. Variations in managers’ wellbeing influenced their mood, energy level, and performance, as well as the company’s working climate. However, these destructive leadership variations did not have a substantial impact, because several protective factors were present. CONCLUSION: This study shows that the wellbeing of managers in small businesses has perceptible consequences for their leadership behaviours. The study also shows that sustained leadership behaviours may coexist with temporary variations of these behaviours on a constructive-destructive continuum depending on the leader’s wellbeing. Overall, the findings contribute to a more nuanced and dynamic understanding of how the interaction between managers’ wellbeing and their behaviours unfolds in the particular context of small companies.
Optimization of the arrangement of ring-spice-rod fixators on the experimental data base during the treatment of tibia nonunion
Authors: Baida Maxim , Rushay Anatoliy , Martinchuk Alexander , Musiienko Olha
Published: December 2022

the problem of tibial bone non-unions after fractures is an actual and not finally solvedproblem. The use of ring spoke-rod devices is the leading method of treatment. Improvement of thistechnology is a generally accepted direction to improve the results of treatment. The aim of the work

was to improve the results of the treatment of non-unions of the lower leg bones based on the im-provement of the fixation technology of ring retainers. In order to fulfill the task of the research, the

problematic issues of fixation of non-unions of lower leg bones after fractures with spoke-rod ringdevices were studied; the formulated concept of solving the existing shortcomings of the method inthe experiment; clinical applications and analysis of the obtained results. The influence of the spatial

fixation of the rod in the ring fixator of the spoke-rod type was determined experimentally. The sub-ject of the study was a Sawbones® synthetic bone with a fracture model, which was fixed with a ring

fixator of the spoke-rod type by 2 models. In our «apparatus-bone» fixation experiment, all the mainparameters of both models (number of rings, spokes, angles of intersection of spokes and fractureplanes) were similar. The difference between the two models was only in the presence or absence of a

stiffener for fixing the rod. 60 victims met the criteria for inclusion in the study. 31 patients were op-erated on with the use of ring devices with increased rigidity of rod fixation according to the proposed

method; they formed the main group. 29 patients - the comparison group, the treatment was carriedout according to the generally accepted method using fixation of the rod without a rib of «stiffness».Clinical evaluation of the results was carried out using the anatomic-functional scale of the ModifiedFunctional Evaluation System by Karlstrom-Olerud. The obtained experimental data indicated an

improvement in the stiffness parameters of the spoke-rod system when using rod fixation with a stiff-ening rib. The greatest effect was obtained during the bending test - the indicator increased from 0.91

to 1.19 H/mm (by 23.53%). The results of clinical effectiveness obtained by us (good and excellent

77.8%; unsatisfactory in 2.8%) can be compared with the data of most researchers. Anatomic-func-tional results in the main group with a high probability (95%) exceeded the results in the comparison

group. Experimental data were confirmed by clinical results. The anatomic-functional results in the

main group according to the values of the estimated anatomic-functional scale of the Modified Func-tional Evaluation System by Karlstrom-Olerud with a high probability (>95%) exceeded the results

in the comparison group. Bearing in mind the severity of the lesion, we consider the obtained clinicalresults to be encouraging. Application of the proposed improvements and further investigation oftheir effectiveness should be recommended.
Market analysis of medicinal products with nimesulide
Authors: Dykun Darya , Tarapon Kateryna , Tryhubchak Oksana
Published: December 2022

nimesulide-containing medicinal products are the most popular non-steroidal anti-in-flammatory drugs which have been widely used in practice for many years. This active substance

belongs to selective cyclooxygenase 2 inhibitors is a powerful pain reliever characterized by a rapidtherapeutic effect compared to other pain relievers. Despite the contradictory literature data of the lastdecades regarding the use of nimesulide due to its hepatotoxic effect, nimesulide medicine remain a

priority in the treatment of patients with pain syndrome of various genesis all over the world. Current-ly, nimesulide is produced in the world in various dosage forms. Some studies in recent years have

proved its antitumor effect which has led to the appearance of new specific forms with nimesulidesuch as microgranules, microspheres, nanoparticles with targeted delivery. Therefore, the purpose ofthe investigation was to analyze Ukrainian pharmaceutical market of products with the nimesulideactive substance by dosage forms, manufacturers; to establish the quality composition of original andgeneric drugs. The objects of the study were medicinal products containing nimesulide registered in

Ukraine. The study was performed by analyzing of register data, using methods of grouping, compar-ison, graphic analysis, and generalization. In the work an analysis of medicines with nimesulide by

dosage form and manufacturers was carried out. The excipients composition of reference drugs fornimesulide granules for oral suspension was also investigated. It was established that 32 medicines

with nimesulide are registered in Ukraine, including 28 mono-preparations. A significant part of me-dicinal products with nimesulide are solid dosage forms, namely tablets (47 %) or granules for oral

suspension (22 %) which contain 100 mg of nimesulide. It was established that there are no nime-sulide in the form of prolonged-release tablets on the domestic market. Nimesulide drug products of

foreign producers are dominant (59.38 %), India has a leading position (50 %). Granules are mainlyproduced by foreign manufacturers that confirms the feasibility of developing a domestic generic

product. The original product is Aulin, granules for oral suspension, “Angelini Pharma”, Czech Re-public. Differences in the qualitative composition of excipients of the original and generic products

which present on the Ukrainian market were observed. The composition of products more often

includes sucrose as filler, сetomacrogol 1000, liquid glucose spray-dried, maltodextrin, sodium sac-charin, anhydrous citric acid, orange flavoring, corn starch, or Aerosil 200. As follows, the feasibility

of development of domestic medicinal product in the form of prolonged-release tablets and granuleswas confirmed; the original product of nimesulide granules for oral suspension was determined andthe qualitative composition of the reference drugs was established.
Vamos falar de saúde mental infantil? Um estudo do impacto de formação especializada em saúde mental infantil para médicos e técnicos de cuidados de saúde primários
Authors:   Hospital Dona Estefânia, Amaro Rita , Pinto Sofia Vaz ,   Hospital Dona Estefânia, Ribeiro Catarina Garcia ,   Hospital Dona Estefânia, Magalhães Maria Francisca ,   Hospital Dona Estefânia, Duarte Nuno Araújo ,   Hospital Dona Estefânia, Sanchez Juan ,   Hospital Dona Estefânia, Silva Pedro Caldeira da ,   Hospital Dona Estefânia
Published: December 2022

Introdução: A intervenção em saúde mental na infância e adolescência deve ser uma prioridade, tendo em conta a elevada prevalência das perturbações mentais nesta faixa etária associadas a uma alta taxa de comorbilidade e a tendência à cronicidade de psicopatologia para a idade adulta. A literatura realça a importância de descentralizar os cuidados de saúde mental infantil, promovendo uma intervenção baseada na comunidade e em interface entre os serviços especializados e os cuidados de saúde primários. Métodos: Realização de uma formação sobre saúde mental infantil, dirigida a médicos e técnicos dos cuidados de saúde primários. Os participantes, no início e no final do curso, responderam a um questionário de 22 perguntas, elaborado pela comissão científica. Os resultados foram avaliados através do Teste Qui Quadrado de Pearson. Resultados: Do total de 120 participantes, 109 questionários foram preenchidos no início (90% dos participantes) e 97 questionários foram preenchidos no final da ação de formação (81% dos participantes). A diferença na pontuação dos questionários inicial e final global foi estatisticamente significativa (valor p<0,05, intervalo de confiança de 95%), sendo a média de respostas corretas dos questionários iniciais de 75,15% e dos questionários finais de 86,40%. Em 15 das 22 questões foi obtida uma diferença estatisticamente significativa. Discussão e Conclusão: Tendo em consideração os resultados é possível reconhecer o impacto significativo que esta formação parece ter tido na aquisição de novos conhecimentos em saúde mental infantil. A equipa de cuidados de saúde primários é uma área privilegiada de articulação, com o potencial de promover estratégias de prevenção e promoção da saúde mental, identificar os problemas precocemente, intervir nos casos menos graves e referenciar aos serviços especializados atempadamente. A equipa de saúde mental deve colaborar com as diferentes estruturas comunitárias, em consultoria, formação, coordenação ou catalisação de iniciativas ou projetos.
The Quantum Character of Perception: The Probabilistic and Reversible Thermodynamic Cycle can Produce Spin-like Attitudes, Thinking, and Behavior
Authors: Deli Eva
Published: December 2022

One of the most puzzling questions in neuroscience is the nature of emotions and their role in consciousness. The sensory system's energy/information exchange revolves around a stable resting state. Therefore, cognitive perception represents information-energy exchange with the environment, giving rise to a closed thermodynamic cycle, which can be modeled by the reversible Carnot engine. The brain's significant energy investment in maintaining the resting state indicates its essential role as the ground state of consciousness, the source of our sense of self. Perception forms either an endothermic or exothermic cycle. The first represents high entropy resting state with irreversible activations, generating novelty and intellect. In the second case, low entropy and reversible resting state cause past focus, regret, and remorse. The reversible thermodynamic cycle, a classical system, takes on quantum characteristics. The cycle's direction generates an orthogonal force or torque, manifested as psychological spin. The endothermic cycle produces up-spin, whereas the exothermic cycle is called down-spin. The quantum and classical natures represent a particle-like duality between continuous and discrete states explained by the fermionic hypothesis. Therefore, emotions are the brain's homeostatic master regulators. They maintain particle-like stability manifested by cognitive comfort by utilizing physiological and hormonal regulation.
THE EUROPEAN UNION (EU) AND THE CLIMATE-SECURITY NEXUS: CSDP MISSIONS AND OPERATIONS
Authors: GENÇ YILMAZ Ayfer
Published: December 2022

Since the mid-2000s, the climate-security nexus has come to the forefront of scholarly debates. For some scholars, the linkages between climate change and security should be analyzed from the national security perspective, whereas others from a human security perspective. Taking into consideration the implications of climate change on national and human security, international organizations worldwide started to develop policies in this field. The EU acknowledges climaterelated security risks and searches for new policies and tools to respond to them. Yet, the EU’s efforts remain mainly at the discursive level. On the practical level, the EU’s various policy tools have not yet incorporated climate-security nexus in their agenda. This paper aims to analyze the impact of the climate-security nexus on the EU’s CSDP missions and operations.
THE DEVELOPMENT OF EU CYBERSECURITY POLICY: FROM A COORDINATING ACTOR TO A CYBER POWER?
Authors: RENDA Kadri Kaan
Published: December 2022

The aim of the article is to elaborate on the institutional and normative evolution of the European Union (EU) cybersecurity policy. The article primarily argues that the EU’s approach to cyberspace has recently focused on economic and security concerns. Secondly, the article contends that the actorness of the EU in the cyberspace has been evolved from a coordinating role to a more powerful one. The article is structured as follows: In the first part of the article, the literature on the EU’s actorness in cyberspace is reviewed. In the second part, the institutional and normative development of EU cybersecurity policy is evaluated. Three strategy papers published by the European Commission in 2013, 2017, and 2020 are elaborated, respectively.
Efectos de un programa de ejercicio físico funcional sobre el equilibrio, la estabilidad dinámica y la fuerza de extremidad inferior en Bomberos de la Quinta Compañía de la ciudad de Talca
Authors: Troncoso Carlos , Gómez David
Published: December 2022

Objetivos (s): El propósito del estudio fue determinar el efecto de un programa de entrenamiento físico funcional en el equilibrio, la estabilidad dinámica y la fuerza de extremidad en bomberos de la Quinta Compañía de la ciudad de Talca. Metodología: El diseño es estudio es cuasi-experimental, cuantitativo, intrasujeto, de corte longitudinal, mediante un programa de ejercicio físico funcional de cuatro semanas de duración, en las que se evaluó indicadores como el equilibrio, la estabilidad y la fuerza de extremidad inferior. Fueron incluidos 12 voluntarios mayores de 18 años, que se mantenían como bomberos activos de la compañía, sin presentar discapacidad física crónica o aguda, los que habían firmado el consentimiento y habían cumplido con las evaluaciones de la condición física. Resultado: Los datos obtenidos mostraron una distribución normal, con un nivel de confiabilidad del 95%. Las cifras obtenidas para las variables de equilibrio y fuerza de extremidad inferior obtuvieron una diferencia significativa p < 0,05, a excepción de la estabilidad dinámica anterior y postero medial p > 0,05. Conclusión: El programa de ejercicio físico funcional generó cambios significativos en el equilibrio y la fuerza de extremidad inferior, no así en la estabilidad dinámica.
PROJECT WORK WITH THE USE OF INFORMATION AND COMMUNICATION TECHNOLOGIES AT FOREIGN LANGUAGE LESSONS IN TERMS OF NEW UKRAINIAN SCHOOL DEVELOPMENT
Authors: Patramanska Iryna
Published: December 2022

The article examines the peculiarities of project work using modern information and communication technologies in foreign language lessons. This article is aimed at analyzing the specific features and possibilities of project work using information and communication technologies in foreign language lessons in the context of the development of the New Ukrainian School. A theoretical analysis of the scientific literature on the outlined issues was carried out. The expediency of project work for teaching elementary, middle and high school students is substantiated. The effectiveness of the use of various information and communication technologies in the students’ project work is analyzed and their main functions that contribute to the implementation of the educational project are indicated. The types of projects that can be used in the implementation of project work using information and communication technologies in foreign language lessons are characterized. Emphasis is placed on the main functions and possibilities of applying project work using information and communication technologies in foreign language lessons. Difficulties that may arise for schoolchildren during project work in foreign language lessons are indicated. Attention was drawn to the fact that project work with the use of modern information and communication technologies in foreign language lessons should not be implemented on a regular basis, such activity should be auxiliary. The materials of this article can be used by teachers who deal with the problems of learning foreign languages in modern educational institutions. The content of the article can serve as an auxiliary methodical and didactic material in the context of the professional activity of teachers of general secondary education institutions.
Drug rash with eosinophilia and systemic symptoms syndrome in an elderly man on carbamazepine – A jeopardising clinical entity
Authors: George Alna Merin , Khader Abdul , CS Sarojiniamma
Published: December 2022

Drug rash with eosinophilia and systemic symptoms syndrome (DRESS) is a rare but serious hypersensitivity drug reaction most frequently associated with antiepileptics. We report a case of carbamazepine-induced DRESS syndrome in a 61-year-old man who was recently initiated on carbamazepine (6 weeks back) and presented with a history of acute febrile illness of 10 days duration. General examination showed multiple erythematous coalescent papules and rash over the body with relative sparing of the face with lymphadenopathy. Laboratory results revealed eosinophilia, atypical lymphocytosis, transaminitis, and negative serology for hepatitis. Registry of severe cutaneous adverse reactions (RegiSCAR) scoring system case is categorized as a definite case with a score of 7. Carbamazepine was discontinued and with the initiation of intravenous steroids; the transaminitis improved, fever and rashes resolved. We report a case of carbamazepine induced DRESS syndrome in a 61-year-old man. He was recently initiated on carbamazepine (6 weeks back), who presented to with a history of acute febrile illness of 10 days duration. General examination showed multiple erythematous coalescent papule and rash over the body with relative sparing of face with lymphadenopathy. Laboratory results revealed an eosinophilia, atypical lymphocytosis, transaminitis and negative serology for hepatitis. RegiSCAR scoring system was used our case is categorized as definite case with a score of 7. Carbamazepine was discontinued and with initiation of intravenous steroids; the transaminitis improved, fever and rashes resolved.
Geomechanical characterization of samples in the pilot zone of Bogotá, Colombia, to determine its potential as aggregates for construction
Authors: Troncoso Rivera Juan Ricardo , Páez Fonseca Nelly , Másmela Rodríguez Óscar René , Fuentes Aldana Leonardo , Terraza Melo Roberto
Published: December 2022

Este proyecto tiene como propósito evaluar y determinar zonas potenciales para la explotación de este tipo de recurso mineral, considerando que los materiales aptos para la construcción son un renglón estratégico para el desarrollo del país. En ese sentido, se evaluó la zona piloto de Bogotá definida por un radio de 200 km alrededor de Bogotá, en la cual se estudiaron las unidades litoestratigráficas con potencial para agregados pétreos en áreas libres de licenciamiento minero, mediante muestreos para ensayos geotécnicos. Se recolectaron 198 muestras, a las cuales se les realizó el proceso de reducción de tamaño o trituración; posteriormente se ejecutó el ensayo de granulometría para clasificar las muestras por tamaños, y finalmente se realizó el ensayo de desgaste (dureza) y ensayo de equivalente de arena (limpieza). Una vez realizados los ensayos, se interpretaron los resultados para definir el uso potencial como agregados gruesos (tamaños en el rango de 75 a 4,75 mm) y agregados finos (tamaños en el rango de 4,75 a 0,075 mm), de acuerdo con las Especificaciones generales de construcción del Instituto Nacional de Vías de Colombia (Invías). En términos de dureza y limpieza, el 60 % de las muestras recolectadas en la zona piloto de Bogotá se puede usar para la producción de agregados. Se definieron 118 sitios potenciales para explotación de agregados gruesos y 19 sitios potenciales para explotación de agregados finos.
Sistemas de proteção ambiental em aterros sanitários
Authors: Silva Bryan Almeida da
Published: December 2022

O aterro sanitário é uma obra de engenharia e atualmente a solução mais adequada em termos ambientais para a disposição final de resíduos sólidos gerados diariamente nos centros urbanos. Pois através da utilização de técnicas construtivas é que se torna possível implantar e operar de forma correta atendendo a todos os requisitos exigidos por lei, assim como, todos os parâmetros ambientais. Diante dessa premissa, qual o método mais adequado para garantir a proteção e a segurança ambiental de um aterro sanitário? Desse modo, surge a necessidade da implementação e utilização do sistema de proteção ambiental, o qual é objeto de estudo deste artigo e tem como objetivo demonstrar as técnicas construtivas que o compõe. A metodologia utilizada foi baseada em pesquisas bibliográficas com o objetivo de ampliar os conhecimentos sobre aterros sanitários. Para isso, as buscas foram concentradas principalmente em livros, revistas, artigos, dissertações, teses de mestrado e leis que abordam temas voltados à política nacional de resíduos sólidos urbanos. Além de normas técnicas brasileiras que preceituam parâmetros de projetos, implantação e operação de aterros sanitários. Os resultados obtidos, mostram que sem a utilização correta desse sistema, a segurança ambiental pode ser comprometida causando sérios danos ao ecossistema e, por sua vez, a população. Portanto, o sistema de proteção ambiental torna-se imprescindível para garantir a correta destinação de resíduos sólidos urbanos e a segurança ambiental em aterros sanitários.
How Inflation Varies Across Spanish Households
Authors: Basso Henrique S. , Dimakou Ourania , Pidkuyko Myroslav
Published: December 2022

Inflation has distributional effects. Leveraging data on consumption expenditure of goods across households provided in the Spanish Household Budget Survey we estimate household-specific inflation from 2006 to 2021 in Spain and analyse how it varies according to households’ known characteristics. We show that households with lower income, more members and whose head is less educated, older, and male experience higher inflation. Finally, we also depict the effects of the most recent price increases across households.