bluuebunny/crossref_metadata_2025 huggingface dataset:
Characteristics of thromboprophylaxis in elderly patients before and after orthopedic hip and knee surgery
Authors: Đenić Aleksandar
Published: December 2022

Elderly patients with a hip fracture are at significantly higher risk for developing venous thromboembolism (VTE). The incidence of fatal pulmonary embolism (PE) occurs in 2-3% of patients after elective hip and knee surgery and about 6-7% after hip fracture surgery, with a higher risk in men (10,2%) than in women (4,7%). The use of pharmacological prophylaxis significantly reduces the incidence of symptomatic VTE. Pharmacological prophylaxis includes the use of antiplatelet drugs (aspirin), unfractionated heparin (UFH), low molecular weight heparins (LMWH), vitamin K antagonists (VKA), Fondaparinux and direct oral anticoagulants (DOAC). The use of low molecular weight heparins (LMWH) - enoxaparin, represents the gold standard of thromboprophylaxis in orthopedic surgery, and for now, they are the only drugs that are recommended for thromboprophylaxis in hip fracture surgery. Rivaroxaban is used in the prophylaxis of VTE in elective hip and knee surgeries at a fixed dose of 10 mg once daily, and apixaban at a dose of 2,5 mg twice daily in knee arthroplasty for at least 14 days, and after hip arthroplasty for at least 35 days. Early hip fracture surgery as soon as possible, preferably within 24 hours, and no later than 48 hours after admission to the hospital, significantly reduces the morbidity and mortality of elderly patients.
Status report on the final round of the NIST lightweight cryptography standardization process
Authors: Sonmez Turan Meltem , McKay Kerry , Chang Donghoon , Bassham Lawrence E , Kang Jinkeon , Waller Noah D , Kelsey John M , Hong Deukjo
Published: December 2022

The National Institute of Standards and Technology (NIST) initiated a public standardization process to select one or more schemes that provide Authenticated Encryption with Associated Data (AEAD) and optional hashing functionalities and are suitable for constrained environments. In February 2019, 57 candidates were submitted to NIST for consideration. Among these, 56 were accepted as first-round candidates in April 2019. After four months, NIST selected 32 of the candidates for the second round. In March 2021, NIST announced 10 finalists - namely ASCON, Elephant, GIFT-COFB, Grain-128AEAD, ISAP, PHOTON-Beetle, Romulus, SPARKLE, TinyJAMBU, and Xoodyak - to move forward to the final round of the selection process. On February 7, 2023, NIST announced the decision to standardize the ASCON family for lightweight cryptography applications. This report describes the evaluation criteria and selection process, which is based on public feedback and internal review of the finalists.
ANÁLISIS DEL MOVIMIENTO FEMINISTA ESTUDIANTIL DEL 2018 EN LA PRENSA CHILENA Y DE LA REGIÓN DE LOS RÍOS
Authors: Browne Rodrigo , Romero Pamela , Rutherford Constanza , Vergara Joaquín
Published: December 2022

Esta investigación analizó la cobertura y la representación que se le dio al movimiento estudiantil feminista chileno del 2018 en la prensa de carácter nacional, centrándose en los cuatro diarios más importantes del país: El Mercurio, La Tercera, La Cuarta y Las Últimas Noticias, así como también en el estudio de dos medios digitales: Biobiochile.cl y Emol.com. Además, se estudió localmente esta movilización a través del Diario Austral Región de Los Ríos, ubicado en Valdivia, ciudad donde comenzaron las demandas estudiantiles de carácter feminista, al alero de la Universidad Austral de Chile.

El interés radicó en comprender cómo los medios están enfrentando estas movilizaciones sociales, y conocer si están entregando una mirada pluralista sobre el tema y los actores involucrados o si, más bien, estuvieron entregando una visión sexista, estereotipada y discriminadora a la ciudadanía a través sus publicaciones noticiosas.

Para ello, se recurrió a la metodología de los estudios del discurso, apuntando los esfuerzos del equipo de investigación al beneficio de una visión crítica sobre los discursos y medios de comunicación analizados.
LAS DOS CARAS DE LA CULTURA FESTIVA ALTERNATIVA. EL MOVIMIENTO FREE PARTY COMO ESPACIO DE CONFORMACIÓN DE NUEVAS IDENTIDADES Y SUBJETIVIDADES FEMENINAS.
Authors: Ruiz Gonzalez Andrea
Published: December 2022

La participación femenina no ha sido suficientemente estudiada en el ámbito de la cultura festiva, ni en expresiones subculturales como el movimiento Free Party, donde la invisibilidad social es una característica imprescindible en la perdurabilidad de la escena, lo que complica más aún las investigaciones respecto a la cuestión de género. En el presente artículo partiremos de la centralidad que adquiere esta experiencia contracultural en la conformación de las identidades de estas mujeres, apostando por un cambio de enfoque cultural feminista. Tomando el marco interpretativo del ritual de interacción de Randall Collins, para deconstruir los mecanismos de participación patriarcales que se dan en la escena Free Party, advirtiendo de la sutileza de estas superestructuras naturalizadas, en torno a un movimiento heterogéneo donde todo vale, pero que esconde roles de participación y usos del espacio, que no concuerdan con el discurso político del movimiento.
Produksi Hidrolisat Protein Kacang Koro Benguk dengan Aktivitas Penghambat Kerja Enzim Pengkonversi Angiotensin melalui Kombinasi Fermentasi dan Hidrolisis Enzimatik
Authors: Pratami Tesy , Sitanggang Azis Boing , Wijaya Christofora Hanny
Published: December 2022

Mucuna bean (Mucuna pruriens L.) is a legume having high protein content which has the potential as a source of bioactive peptides. One of the bioactive peptides is an angiotensin-converting enzyme (ACE) inhibitor, thus, mucuna beans might be used as a potential source of antihypertensive compounds. This study aimed to increase the functionality of proteins from mucuna beans as ACE inhibitors using a combination of fermentation and enzymatic hydrolysis followed by membrane filtration. The mucuna beans were fermented for 0, 24, 48, 96, and 144 h. The highest ACE inhibitory activity of 54.37%, was obtained by fermentation of the beans at 48 h, with a protein content of 20.82 mg/mL. The 48 h fermented mucuna beans were further hydrolyzed using alcalase or neutrase and subsequently filtered with UF membranes having 20,10 and 5 kDa cut-off. The enzymatic hydrolysis followed by membrane filtration increased the ACE inhibitory activity of mucuna beans. The neutrase hydrolysates resulting from 5 kDa membrane filtration showed the best ACE inhibitory activity (62.96% with a protein content of 10.39 mg/mL). A combination of fermentation and enzymatic hydrolysis followed by filtration using UF-membrane was able to produce ACE inhibitory peptides from mucuna beans. The potential of mucuna beans peptides as ACE inhibitors was due to the presence of negatively charged amino acid residues such as Asp and Glu, positively charged amino acids such as Arg and Lys, and hydrophobic amino acids such as Val, Leu, Ala, and Ile.
Oral Health Related Quality of Life in first-time denture wearers Using Balanced, Monoplane and Group function Occlusion
Authors: PARAKH Mayank Kumar , D Krishna Prasad , DEMERİE Farah
Published: December 2022

Background: Oral Health Impact profile is one of the most common methods to assess the Oral Health Related Quality of Life (OHRQoL) of the patients.

Methods: In this study, a total of 66 edentulous participants were included and divided into 3 groups of 22 each using simple random sampling. OHIP-14 scores were assessed before complete denture treatment and at 6 months follow-up.

Results: When comparison of mean OHIP – 14 among the study population across gender before and after denture insertion was done the results were statistically significant. (P-value- 0.001) The difference between the follow-up scores and the scores before a denture when subjected to statistical analysis was significant for all three groups. When one-way ANOVA was done between the groups the data was statistically significant. (P-value
Is sclerostin antibody an effective agent for alveolar bone regeneration in animal models? A scoping review
Authors: BANU Sunaina , PUZHANKARA Lakshmi , KEDLAYA Madhurya N , VARGHESE Jothi M , RAMANARAYANAN Venkitachalam
Published: December 2022

Objectives

The use of Sclerostin Antibody(Scl-Ab) as a bone anabolic agent has shown significant benefit in bone disorders in preclinical animal models and human clinical trials. Currently available evidence on the use of Scl-Ab in alveolar bone regeneration is limited to animal studies and hence this scoping review encompasses the animal studies conducted to ascertain the effectiveness of Scl-Ab on alveolar bone regeneration.

Materials and methods

The search strategy was aimed to locate published animal studies in which the treatment arm includes Sclerostin antibody administration for alveolar bone preservation or regeneration. The search terms used were (((Animal model) OR Rodent) AND Alveolar bone defect) AND Anti sclerostin antibody) OR Sclerostin antibody) AND Alveolar bone regeneration) OR Bone regeneration) AND Bone fill.

Results

Of the 559 results from Medline/PubMed, Scopus, Web of Science, Google scholar and additional articles from the references, six were included in the review. Scl-Ab was found to be effective in improving the bone quality and quantity. It was also observed that Scl-Ab was useful in reduced bone density associated with diseases and conditiona affecting osteoblast activity.

Conclusion

The review concluded that Scl-Ab promotes alveolar bone augmentation and improves bone quality without surgical interventions.
Nasoethmoid orbital fracture reconstruction using a three-dimensional printing-based craniofacial plate
Authors: Hong Hyun Ki , Kim Do Gon , Choi Dong Hun , Seo Anna , Chung Ho Yun
Published: December 2022

The face is one of the most important parts of the body. Untreated facial fractures can result in deformities that can be harmful to patients. Three-dimensional (3D) printing is a rapidly evolving technology that has recently been widely applied in the medical field as it can potentially improve patient treatment. Although 3D printing technology is mostly used for craniofacial surgery, some studies have proved that it can be used to treat nasoethmoid orbital fractures. In this study, a patient-customized plate was constructed using a 3D printer and applied in a simulated surgery for the treatment of nasoethmoid orbital fracture.
Treatment of a naso-orbito-ethmoid fracture using open reduction and suspension sutures: a case report
Authors: Na Youngsu , Seo Chaneol , Kwon Yongseok , Kim Jeenam , Choi Hyungon , Shin Donghyeok , Lee Myungchul
Published: December 2022

Naso-orbito-ethmoidal (NOE) fractures are complicated fractures of the mid-face. The treatment of NOE fractures is challenging and a comprehensive treatment strategy is required. We introduce a case of NOE fracture treated with open reduction and suspension sutures. A 28-year-old woman presented with a unilateral NOE fracture. To reduce the frontal process of the maxilla, a suspension suture was made by pulling the fragment using a double arm suture via a transcaruncular incision. The suture thread was placed in the horizontal plane. Another suspension suture on the inferior orbital rim assisted reduction procedure, and they passed through the overlying skin. The reduction alignment could be finely adjusted by tightening the transcutaneous suture threads while checking the degree of bone alignment through the subciliary incision. The two suture threads were suspended using a thermoplastic nasal splint. An additional skin incision on the medial canthal area, which would have resulted in a scar, could be avoided. Four months postoperatively, computed tomography showed an accurate and stable reduction. The patient was satisfied with her aesthetic appearance, and functional deficits were not present.
Sensory change and recovery of infraorbital area after zygomaticomaxillary and orbital floor fractures
Authors: Han Sang Woo , Kim Jeong Ho , Kim Sug Won , Kim Sung Hwa , Kang Dae Ryong , Kim Jiye
Published: December 2022

Background: To compare the sensory change and recovery of infraorbital area associated with zygomaticomaxillary and orbital floor fractures and their recoveries and investigate the factors that affect them.Methods: We retrospectively reviewed 652 patients diagnosed with zygomaticomaxillary (n= 430) or orbital floor (n= 222) fractures in a single center between January 2016 and January 2021. Patient data, including age, sex, medical history, injury mechanism, Knight and North classification (in zygomaticomaxillary fracture cases), injury indication for surgery (in orbital floor cases), combined injury, sensory change, and recovery period, were reviewed. The chi-square test was used for statistical analysis.Results: Orbital floor fractures occurred more frequently in younger patients than zygomaticomaxillary fractures (p< 0.001). High-energy injuries were more likely to be associated with zygomaticomaxillary fractures (p< 0.001), whereas low-energy injuries were more likely to be associated with orbital floor fractures (p< 0.001). The sensory changes associated with orbital floor and zygomaticomaxillary fractures were not significantly different (p= 0.773). Sensory recovery was more rapid and better after orbital floor than after zygomaticomaxillary fractures; however, the difference was not significantly different. Additionally, the low-energy group showed a higher incidence of sensory changes than the high-energy group, but the difference was not statistically significant (p= 0.512). Permanent sensory changes were more frequent in the high-energy group, the difference was statistically significant (p= 0.043).Conclusion: The study found no significant difference in the incidence of sensory changes associated with orbital floor and zygomaticomaxillary fractures. In case of orbital floor fractures and high-energy injuries, the risk of permanent sensory impairment should be considered.
A CASE REPORT OF BEHÇET'S DISEASE WITH CORONARY ARTERY INVOLVEMENT
Authors: SAHİN Ali , ÇABUK ÇELİK Neşe , YALÇIN İlker , KARAKAŞ Burak , KARATAŞ Beliz
Published: December 2022

ABSTRACT

We present a case of coronary artery thrombosis due to Behçet's disease. A 49-year-old female patient, diagnosed with Behçet's disease and followed up by us, applied to the emergency department with sudden onset of pressure-type chest pain, and was evaluated as acute myocardial infarction due to elevated cardiac enzymes and ST segment elevation in the anterior leads on electrocardiography (ECG). Coronary angiography revealed near-total thrombosis in the lumen of the left anterior descending artery (LAD) and in the circumflex (CX) artery,it was intervened with anticoagulant therapy. The patient's cardiac risk was found to be low and differential diagnosis was made in terms of myocardial infarction. Thereupon, the causes of hypercoagulability were investigated in the patient who was consulted to us, and acute phase reactants were found to be high. This was related to the coronary artery involvement of Behçet's disease and in addition to the treatment containing antiaggregant, statin, angiotensin receptor blocker, intravenous (IV) high-dose methylprednisolone and cyclophosphamide-mesna treatment was given for immunosuppressive purposes. It should not be forgotten that there may be vascular involvement due to Behçet's disease and coronary arteries may also be affected.
Visions et représentations du quartier de Chinatown à Paris dans les films français de l’extrême contemporain?: de l’exotisme au multiculturalisme
Authors: Pan Yue
Published: December 2022

Cette étude examine les représentations du triangle de Choisy, le quartier reconnu comme Chinatown de Paris, dans trois films français contemporains : Augustin, roi du Kung-fu (1999), Paris, je t’aime (2006) et Made in China (2019). L’article a pour objectif de montrer le regard, qui se manifeste à travers ces films, porté par le courant dominant de la société française sur cette enclave urbaine et sur la sous-culture sino-française. Avec une analyse des images de paysage urbain du quartier, des personnages masculins occidentaux qui se présentent dans Chinatown et des personnages féminins d’origine asiatique qui habitent ici, l’article présente les représentations cinématographiques de ce Chinatown parisien à travers trois plans : sa postmodernité architecturale, sa fonction dans l’organisation sociale de Paris et son rapport avec le courant dominant de la société française. L’article fait valoir que le Chinatown parisien représente le côté multiculturel de Paris sur l’écran. Ainsi, les images de Chinatown nous permettent d’observer l’évolution du multiculturalisme dans la société française.
La double dominante générique dans 'Zakwato. Pour que ma terre ne dorme plus jamais', Azo Vauguy
Authors: Brou Stéphane Konan Luc
Published: December 2022

Tout texte littéraire se définit proportionnellement à différents prismes dont celui du genre. Il se réalise au moyen d’un code dont la matérialisation est perçue comme une régularité langagière, une dominante. Zakwato. Pour que ma terre ne dorme plus jamais est une œuvre poétique dans laquelle, en marge du code poétique, Azo Vauguy fait également fonctionner, à haut régime, le code narratif qui en devient une seconde dominante. La tension entre la dominante poétique et la dominante narrative fait de cette création verbale un lieu textuel où les frontières génériques sont repoussées à l’extrême. L’article, dans une perspective stylistique, analyse ainsi l’hybridité construite à partir de ces deux dominantes et montre qu’elle participe du dynamisme de la littérarité générique.
Taxation and Tax Administration of Transactions with Crypto Assets in the Positions of the Fiscal Authorities of Russia
Authors: Valova Anna Aleksandrovna
Published: December 2022

The subject of the article is to identify the approaches of the fiscal authorities of Russia to taxation and administration of transactions with crypto assets in relation to various types of taxes. The author set the tasks: to investigate the explanations of the fiscal authorities of Russia regarding the need to impose personal income tax on income received by individuals when performing transactions with crypto assets; to update the position regarding the need to impose corporate income tax on profits received as a result of transactions with crypto assets; to understand the procedure for taxation of income of taxpayers applying special tax regimes; to study the issues of taxation VAT on the sale of crypto assets, the occurrence of property tax on the possession of crypto assets; analyze the need to submit specialized reports to the tax authorities regarding transactions or ownership of crypto assets. The study of the explanations of the fiscal authorities of Russia over the past five years has made it possible to update the positions of the state in terms of taxation and tax administration of transactions with crypto assets in the absence of appropriate rules in tax legislation. The author of the article concluded that, in general, the fiscal authorities consistently consider for various taxes that the general rules established by the tax legislation of the Russian Federation are applicable to the taxation of transactions with crypto assets. The absence of special taxation rules does not mean that there is no need to declare and tax the income received accordingly. At the same time, according to the author, the adoption of relevant regulations regarding the mining of digital currencies, the determination of their legal status for tax purposes would make it possible to remove issues that have not been definitively resolved to date regarding the taxation of the issuance and sale of digital currencies, including the possibility of exemption from personal income tax when owned for more than three years; the use of special tax regimes; there is no need to impose VAT on the relevant transactions, which would correspond to the international experience of taxation of transactions with these assets.
Singular elliptic problems with Dirichlet or mixed Dirichlet-Neumann non-homogeneous boundary conditions
Authors: Godoy Tomas
Published: December 2022

Let \(\Omega\) be a \(C^{2}\) bounded domain in \(\mathbb{R}^{n}\) such that \(\partial\Omega=\Gamma_{1}\cup\Gamma_{2}\), where \(\Gamma_{1}\) and \(\Gamma_{2}\) are disjoint closed subsets of \(\partial\Omega\), and consider the problem\(-\Delta u=g(\cdot,u)\) in \(\Omega\), \(u=\tau\) on \(\Gamma_{1}\), \(\frac{\partial u}{\partial\nu}=\eta\) on \(\Gamma_{2}\), where \(0\leq\tau\in W^{\frac{1}{2},2}(\Gamma_{1})\), \(\eta\in(H_{0,\Gamma_{1}}^{1}(\Omega))^{\prime}\), and \(g:\Omega \times(0,\infty)\rightarrow\mathbb{R}\) is a nonnegative Carath�odory function. Under suitable assumptions on \(g\) and \(\eta\) we prove the existence and uniqueness of a positive weak solution of this problem. Our assumptions allow \(g\) to be singular at \(s=0\) and also at \(x\in S\) for some suitable subsets \(S\subset\overline{\Omega}\). The Dirichlet problem \(-\Delta u=g(\cdot,u)\) in \(\Omega\), \(u=\sigma\) on \(\partial\Omega\) is also studied in the case when \(0\leq\sigma\in W^{\frac{1}{2},2}(\Omega)\).
Nonoscillation of damped linear differential equations with a proportional derivative controller and its application to Whittaker-Hill-type and Mathieu-type equations
Authors: Ishibashi Kazuki
Published: December 2022

The proportional derivative (PD) controller of a differential operator is commonly referred to as the conformable derivative. In this paper, we derive a nonoscillation theorem for damped linear differential equations with a differential operator using the conformable derivative of control theory. The proof of the nonoscillation theorem utilizes the Riccati inequality corresponding to the equation considered. The provided nonoscillation theorem gives the nonoscillatory condition for a damped Euler-type differential equation with a PD controller. Moreover, the nonoscillation of the equation with a PD controller that can generalize Whittaker-Hill-type equations is also considered in this paper. The Whittaker-Hill-type equation considered in this study also includes the Mathieu-type equation. As a subtopic of this work, we consider the nonoscillation of Mathieu-type equations with a PD controller while making full use of numerical simulations.
A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite
Authors: Ramaprasad Abhinay , Burda Paul-Christian , Calvani Enrica , Sait Aaron J , Palma-Duran Susana Alejandra , Withers-Martinez Chrislaine , Hackett Fiona , Macrae James , Collinson Lucy , Gilberger Tim Wolf , Blackman Michael J
Published: December 2022

The malaria parasite Plasmodium falciparum synthesizes significant amounts of phospholipids to meet the demands of replication within red blood cells. De novo phosphatidylcholine (PC) biosynthesis via the Kennedy pathway is essential, requiring choline that is primarily sourced from host serum lysophosphatidylcholine (lysoPC). LysoPC also acts as an environmental sensor to regulate parasite sexual differentiation. Despite these critical roles for host lysoPC, the enzyme(s) involved in its breakdown to free choline for PC synthesis are unknown. Here, we show that a parasite glycerophosphodiesterase (PfGDPD) is indispensable for blood stage parasite proliferation. Exogenous choline rescues growth of PfGDPD-null parasites, directly linking PfGDPD function to choline incorporation. Genetic ablation of PfGDPD reduces choline uptake from lysoPC, resulting in depletion of several PC species in the parasite, whilst purified PfGDPD releases choline from glycerophosphocholine in vitro. Our results identify PfGDPD as a choline-releasing glycerophosphodiesterase that mediates a critical step in PC biosynthesis and parasite survival.
Ultrastructural effects of sleep and wake on the parallel fiber synapses of the cerebellum
Authors: Loschky Sophia S , Spano Giovanna Maria , Marshall William , Schroeder Andrea , Nemec Kelsey Marie , Schiereck Shannon Sandra , de Vivo Luisa , Bellesi Michele , Banningh Sebastian Weyn , Tononi Giulio , Cirelli Chiara
Published: December 2022

Multiple evidence in rodents shows that the strength of excitatory synapses in the cerebral cortex and hippocampus is greater after wake than after sleep. The widespread synaptic weakening afforded by sleep is believed to keep the cost of synaptic activity under control, promote memory consolidation, and prevent synaptic saturation, thus preserving the brain’s ability to learn day after day. The cerebellum is highly plastic and the Purkinje cells, the sole output neurons of the cerebellar cortex, are endowed with a staggering number of excitatory parallel fiber synapses. However, whether these synapses are affected by sleep and wake is unknown. Here, we used serial block face scanning electron microscopy to obtain the full 3D reconstruction of more than 7000 spines and their parallel fiber synapses in the mouse posterior vermis. This analysis was done in mice whose cortical and hippocampal synapses were previously measured, revealing that average synaptic size was lower after sleep compared to wake with no major changes in synapse number. Here, instead, we find that while the average size of parallel fiber synapses does not change, the number of branched synapses is reduced in half after sleep compared to after wake, corresponding to ~16% of all spines after wake and ~8% after sleep. Branched synapses are harbored by two or more spines sharing the same neck and, as also shown here, are almost always contacted by different parallel fibers. These findings suggest that during wake, coincidences of firing over parallel fibers may translate into the formation of synapses converging on the same branched spine, which may be especially effective in driving Purkinje cells to fire. By contrast, sleep may promote the off-line pruning of branched synapses that were formed due to spurious coincidences.
„Freude“ in Edith Steins Philosophie und in religionsphänomenologischem Vergleich.
Authors:   Catholic University of Applied Science, Munich. Alemania., Beckmann-Zöller Beate
Published: December 2022

En la filosofía de Edith Stein se analiza el fenómeno “alegría” como experiencia sentimental unida a aspectos racionales. Bajo este presupuesto, se realiza una investigación desde la fenomenología de la religión acerca del fenómeno de la alegría en algunas religiones, a saber, el cristianismo, el judaísmo, el islam, el hinduismo y el budismo. A partir de algunas fiestas religiosas y su fundamentación religiosa se muestran las ideas centrales de cada una de las religiones. Se hace un énfasis especial en las “fiestas nocturnas” de cada una de las cinco religiones seleccionadas
Un día soleado (2018): el paisaje de lo cotidiano, ecos de una identidad urbano-barrial popular
Authors:   Universidad de O’Higgins (Chile), Ibaceta Isabel , Troncoso Araya Anahí ,   Universidad de O’Higgins (Chile)
Published: December 2022

A partir del análisis del libro-álbum Un día soleado (2018) de Rafael Rubio y Gabriela Lyon reconocemos imaginarios identitarios vinculados a prácticas culturales cotidianas y urbanas, junto con elementos patrimoniales y personajes de raigambre popular que construyen sentidos de lo nacional que se distancian de perspectivas esencialistas. Esta articulación discursiva de lo identitario, proponemos, da cuenta de un giro en la narrativa para las infancias de la última década, la que entre 1990 y 2010 se centró principalmente en visibilizar las culturas nativas, desde una perspectiva en la que predominaba la idea de unificación y homogeneización de la diversidad cultural.
Reliability and Validity of Gujarati Version of WHO-5 Well-being Index in Community-dwelling Older Individuals: A Cross-sectional Study
Authors: Dalal Vipra , Khatri Subhash
Published: December 2022

Introduction: Major mental health issues like depression are not yet acknowledged as considerable public health challenges. The World Health Organization (WHO-5) well-being index is a simple concise questionnaire consisting of five basic questions that evaluate respondents’ subjective well-being. The scale’s internal and external validity are good for assessing depression in older individuals. This scale serves as an essential tool to evaluate various mental health-related issues as part of regular health check-ups. Thus, there was a need to translate and validate the WHO-5 well-being index in the Gujarati language. Aim: To find out the validity and reliability of the Gujarati version of the WHO-5 well-being index in the community-dwelling older individuals. Materials and Methods: This cross-sectional study was conducted among various community-dwelling older individuals in Ahmedabad, Gujarat, India, from March 2022 to August 2022. Permission was taken from the developer of the original scale and translation and validation of the scale were done according to suggestions given by the developer. A total of 60 participants and eight professionals with a mean experience of 13.5 years in the field of psychology, physiotherapy and healthcare area were involved in the examination of each item of the Gujarati version of WHO-5. The Statistical Package for the Social Sciences (SPSS) version 26.0 was used for the statistical analysis. Results: The mean age of the participants was 67.02±4.77 years. The content validity ratio of all items of the Gujarati WHO-5 well-being scale was 1. Internal consistency of the Gujarati WHO-5 well-being scale was calculated through Cronbach’s alpha (α=0.89) suggesting high internal consistency. Test-retest reliability of the Gujarati WHO-5 well-being scale was calculated through the Interclass Correlation Coefficient (ICC=0.89) suggesting excellent test-retest reliability. Conclusion: Gujarati WHO-5 well-being scale is a simple, accurate and reliable measure for evaluating psychological well-being and mental health status.
Bedside Prognostic Indicators of Fatal Outcome among Children with Cerebral Malaria at a Tertiary Nigerian Hospital
Authors: Alabi Ayobami Oyetunji , Onigbinde Michael Olaniyan , Ojuawo Ayodele , Medewase Victor Idowu Joel- , Alabi Grace Olukemi , Oladibu Olanike Taye , Sayomi Bukola Adetutu
Published: December 2022

Introduction: Cerebral Malaria (CM) is a severe manifestation of malaria and commonly causes poor outcomes. It affects upto one million people per year worldwide predominantly sub-Saharan African children. It is clinically expedient that children with CM are identified promptly and easily to halt fatal outcomes. Aim: To evaluate bedside prognostic indicators of poor outcome among children with CM. Materials and Methods: A prospective, observational study was conducted at LAUTECH Teaching Hospital Ogbomoso, Oyo State, Nigeria among children diagnosed with CM from February 2018 to September 2018. Fifty children with age range of 6 months to 12 years were included in the study. Outcome indicators were full recovery, alive with neurological sequelae and death. Nine of the identified clinical factors demonstrable on bedside were assigned score of 1 each and each score summated to form Bedside Prognostic Index (BPI). The median BPI Score ≥4 indicated fatal outcome. Receiver Operating Characteristic (ROC) curve validated the predictive ability of the BPI score on clinical outcomes. Chi-square test and student t-test were used for statistical analysis. Results: Out of total 50 children, 30 (60%) recovered fully, 11 (22%) participants had neurological deficit(s) and 9 (18%) participants died. The median BPI score among completely recovered, survived with neurological deficit(s) and died was 8, 6 and 4, respectively. BPI score ≥4 was an independent predictor of fatal outcome {Odd’s Ratio (OR)=7.875, p-value=0.013, Confidence Interval (CI)=1.547-40.091} with sensitivity and specificity of 80% and 76.67% respectively. The ROC of the predictive ability of BPI on clinical outcomes was 80.2%. Conclusion: Poor outcome was significantly associated with BPI of ≥4 in children with CM. The use of this scoring index should be encouraged to promptly manage children with CM at risk of poor outcome.
Copper Oxide Nanoparticles Induced Liver and Kidney Toxicity in Rat
Authors: El-Atrash Afaf , Zaki Somia , Tousson Ehab , Negm Marwa
Published: December 2022

Aims: Copper oxide nanoparticles (CuO NPs), which have potential hazards for organisms and the environment in a number of applications, have emerged as a prominent class of nanomaterials.

Study Design: This study aimed to investigate the effect of copper oxide nanoparticles in rat liver and kidney tissues.

Methodology: A total of 20 adult male rats were assigned randomly to 2 groups [1st, control; 2nd, CuO NPs (400 mg/kg body weight/day) intraperitoneally for 4 weeks].

Results: Current results revealed significant increases in serum ALT, AST, urea, creatinine, potassium ions and liver and kidney tissue damage after CuO NPs administration when compared to control group. Conversely, statistical significant decreases were detected in serum albumin, total proteins, calcium and sodium ions levels in CuO NPs group as compared to control group.

Conclusion: We can conclude that; CuO NPs induced toxicity and injury in rat liver and kidney tissues.
Environmental Gradient: An Ecological Surrogate to Phytosociological Diversity of a Tropical Mangal-Rainforest-Ecotone in a Hydromesic Tripartite Plant Community
Authors: Lucky Edwin-Wosu, Nsirim , Tosanyemi Mojuetan,
Published: December 2022

Aim: To assess influence of edaphic environmental gradients as surrogate to phytosociological diversity in a hyromesic habitat.

Study Design:  A systematic sampling approach of line-transect method was used.

Place and Duration of Study: Field sampling: tropical mangal-rainforest ecotone in parts of Asarama, Andoni, Niger-Delta, Labortory analysis: Jack Petroanalytical Laboratory, and University of Port Harcourt Ecology Laboratory, Port Harcourt, Nigeria, between September 2020 and August 2021.

Methodology: Soil sampling and analyses was based on ASTM, Stewarte and conventional methods and the data obtained was subjected to statistical analysis.

Results: Recorded 90 plant species across the sampled sites with a prevalence of 6 (65.9%) species in mangrove, 64 (70.33%) in ecotone and 55(60.44%) in rainforest sites respectively. Floristic density and life form in mangrove had 121ha-1, 3 megaphanerophytes and mesophanerophytes respectively, in ecotone 1660ha-1, 9 megaphanerophytes, 24 mesophanerophytes and 39 microphanerophytes and in rainforest 574ha-1, 13 megaphanerophytes, 18 mesophanerophytes and 24 microphanerophytes. Highest frequency of occurrence: 1 species (80%), 4 species (100%) and 1 species (80%) in mangrove, ecotone and rainforest sites, respectively. Highest abundance: mangrove (1 species), ecotone (9 species) and rainforest (3 species). Highest density: mangrove (1 species), ecotone (8 species) and rainforest (3 species). Distribution: greater in ecotone with contiguous pattern in the order: ecotone>rainforest>mangrove, among which had dissimilarity in response to significant species diversity difference in relation to significant difference in edaphic physico-chemical factors of the study sites. The mangrove site had the most acidic pH, highest salinity, moisture and electrical conductivity while rainforest and ecotone had highest organic carbon and matter. A significant negative correlation between EC & pH, and salinity & pH and positive correlation between salinity & EC as well as positive correlation between pH & OC, pH & OM, OC & OM and negative correlation between EC & OC, EC & OM were recorded.

Conclusion: This variation determined the presence, growth and abundance of the species reported in the respective study sites especially in the ecotone.
Seasonal Variation in Physico-chemical Properties of Effluent Generated at a Sewage Treatment Plant in Varanasi and It’s Suitability for Irrigation
Authors: Chourasia Aditi , Singh Anand Prakash , Chattopadhyay Arghya , Behera Tusarkanta , Singh Nitesh Kumar
Published: December 2022

The current investigation was carried out to ascertain the suitability of the influent and effluent of Varanasi's Bhagwanpur sewage treatment plant for irrigation as well as variations in its physicochemical properties throughout the year 2018. The suitability of the water for irrigation was evaluated by taking water samples from the plant's inlet, aerator, and outlet tanks. Then, these samples were examined for heavy metals as well as parameters like pH, EC, TDS, BOD, COD, and dominant anions and cations.The plant's effluent is suitable for irrigating agricultural fields because parameters like pH, nitrate, phosphate, and other cations are below the permissible limit and will provide the necessary nutrients for crops. However, higher concentrations of some heavy metals were a notable concern that will need close attention and ongoing monitoring in the near future if effluent water is to be used for irrigation. The treatment process significantly lowers the effluent water's COD, sulphates, and other ions to levels that allow for surface water discharge, but it leaves the BOD, nitrate, and phosphate content just above levels which are recommended, making it unsuitable for discharge into the holy Ganges since it will cause eutrophication.
A Comparison of the Effect on Postoperative Pain between Lateral Femoral Cutaneous Nerve Block and Local Infiltration Anesthesia after Total Hip Arthroplasty: A Randomized Trial
Authors: Shimasaki Ayako , Terao Yoshiaki , Komatsu Yuya , Kasai Yusuke , Oji Natsuko , Oji Makito , Aoki Hiroshi , Hara Tetsuya
Published: December 2022

Aims: No gold standard for pain management after total hip arthroplasty (THA) exists. This prospective, randomized, open-label study aimed to determine whether lateral femoral cutaneous nerve block and local infiltration analgesia (LIA) were effective analgesic adjuvants to femoral nerve block (FNB) after THA.

Study Design: Prospective, randomized, open-label trial.

Place and Duration of Study: Department of Anesthesia, Nagasaki Rosai Hospital, Sasebo, Japan between April 2019 and May 2020.

Methodology: This study included 50 patients who underwent THA under total intravenous anesthesia using propofol. All patients received ultrasound-guided FNB using 0.25% levobupivacaine 20 mL before the operation. Patients were randomly allocated to one of the following two groups: Group B (n=25), which received ultrasound-guided lateral femoral cutaneous nerve block with 0.25% levobupivacaine 20 mL after FNB; and Group I (n= 25), which received 0.25% levobupivacaine 20 mL over the incision line into the muscle, and the subcutaneous, and cutaneous tissue along the wound edge after the fascia closure. All patients received 1000 mg intravenous acetaminophen before the end of the operation, and at 6, 12, 18, and 24 h after the operation. The patients received 50 mg of diclofenac sodium, as rescue analgesics, if needed. Nursing staff evaluated the postoperative pain using a numerical rating scale (NRS) at 0, 1, 3, 6, 12, 18, and 24 h postoperatively.

Results: No significant difference was observed in patient characteristics, except the operative time, between the groups. Additionally, no significant difference was found in NRS and in the frequency of rescue analgesics during the study period between the groups.

Conclusion: We concluded that both lateral femoral cutaneous nerve block and LIA with FNB would have the equivalent adjunctive analgesic effect after THA.
In-Hospital and Short-Term Outcomes of Percutaneous Coronary Intervention in Patients Older Than 65 Years Old: Results from Tanta PCI Registry
Authors: Kasem Mohammed Salah , Badr Seham Fahmy , Kassem Hanan Kamel , El-Amrosy Mahmoud Zaki , Abdel-Majid Randa Mohammed
Published: December 2022

Background: Percutaneous coronary intervention (PCI) outcomes in elderly people are more challenging due to several factors. This study aimed to investigate in-hospital and short-term outcomes of PCI in elderly people aged more than 65 years old, presented to cardiology department of Tanta university hospitals during study period.

Methods: This case-control study was carried out on 935 patients presenting for elective PCI procedure and those suffering from high-risk ACS either ST segment elevation myocardial infarction (STEMI), non-ST segment elevation myocardial infarction (NSTEMI) or unstable angina treated with urgent PCI. Patients were divided into 4 groups: group II: included 326 patients aged from 65 to 69 years old, group III: included 160 patients aged from 70 to 74 years old, group IV: Included 99 patients aged ≥ 75 years old and group I (control): included 350 patients aged < 65 years old. All patients were subjected to ECG, echocardiography, basic labs, coronary angiography and PCI.

Results: Mortality, dissection, perforation, CIN, hemorrhage, heart failure and cardiogenic shock were significantly different among STEMI patients’ groups (P ≤ 0.05). CVS, Heart failure and Cardiogenic shock were significantly different among NSTE-ACS patients’ groups (P ≤ 0.05). Loss of follow up and mortality were significantly different among NSTE-ACS patients’ groups. Age, diabetes mellitus, hypertension, multi-vessel diseases, dissection, perforation and major bleeding were significant predictors of mortality among elective PCI patients (P ≤ 0.05). Age, diabetes mellitus, hypertension, chronic kidney diseases that necessitates dialysis, dyslipidemia multi-vessel diseases, left main artery, final TIMI 0, final TIMI I dissection, perforation, and major bleeding were significant predictors of mortality among ACS PCI patients (P ≤ 0.05).

Conclusions: In spite that PCI in elderly people still challenging, with poorer outcomes especially among those older than 75 years of age, newer generations of drug-eluting stents, and wide-availability of the safer radial artery access reduced the risk of PCI-related major adverse cardiovascular events and improved the long-term clinical outcomes in elderly patients suffering from both high-risk chronic and ACS.
A Study on the Methods to Improve High-Wave Reproducibility during Typhoon
Authors: Back Jong-Dai , Ryu Kyong-Ho , Lee Jong-In , Jeong Weon-Mu , Chang Yeon-S.
Published: December 2022

This study estimates the design wave in the event of a typhoon attack at Busan new port using the wind field, the revised shallow water design wave estimation method proposed by the Ministry of Oceans and Fisheries in 2020, and proposed a reliable method of calculating the shallow water design through verification with the wave observation data. As a result of estimating typhoon wave using the wind field and SWAN numerical model, which are commonly used in the field work, for typhoon that affected Busan new port, it was found that reproducibility was not good except typhoons KONG-REY(1825) and MAYSAK(2009). In particular, in the case of typhoon MAEMI(0314), which had the greatest impact on Busan new port, the maximum significant wave height was estimated to be about 35.0% smaller than that of the observed wave data. Therefore, a plan to improve the reproducibility of typhoon wave was reviewed by applying the method of correcting the wind field and the method of using the Boussinesq equation numerical model, respectively. As a result of the review, it was found that the reproducibility of the wind field was not good as before when the wind field correction. However as a method of linking wind field data, SWAN model results, and Boussinesq numerical model, typhoon wave was estimated during typhoon MAEMI(0314), and the maximum significant wave was similar to the wave observations, so it was reviewed to have good reproducibility.
Comparative Analysis of Forecasting Accuracy and Model Performance for Development of Coastal Wave Forecasting System Based on Unstructured Grid
Authors: Roh Min , Oh Sang Myeong , Chang Pil-Hun , Kang Hyun-Suk , Kim Hyung Suk
Published: December 2022

We develop a coastal wave forecasting system by using the unstructured grid based on sea wind data of Global Data Assimilation and Prediction System. The verification is performed to examine the performance and accuracy of the wave model. Since the conventional grid has limited wave forecasting on complex coastlines and bathymetry, the unstructured grid system is applied for precise numerical simulation, and applicability for operational support is evaluated. Both grid systems show similar prediction trends in offshore and coastal areas, and the difference in prediction errors according to the grid system is not large. In addition, the applicability of the operational wave forecasting system is confirmed by dramatically reducing the model execution time of the unstructured grid under the same conditions.
Current Status and Future Plans for Surface Current Observation by HF Radar in the Southern Jeju
Authors: Jung Dawoon , Kim Jae Yeob , Kwon Jae-il , Song Kyu-Min
Published: December 2022

The southern strait of Jeju is a divergence point of the Tsushima Warm Current (TWC), and it is the starting point of the thermohaline circulation in the waters of the Korean Peninsula, affecting the size and frequency of marine disasters such as typhoons and tsunamis, and has a very important oceanographic impact, such as becoming a source of harmful organisms and radioactively contaminated water. Therefore, for an immediate response to these maritime disasters, real-time ocean observation is required. However, compared to other straits, in the case of southern Jeju, such wide area marine observations are insufficient. Therefore, in this study, surface current field of the southern strait of Jeju was calculated using High-Frequency radar (HF radar). the large surface current field is calculated, and post-processing and data improvement are carried out through APM (Antenna Pattern Measurement) and FOL (First Order Line), and comparative analysis is conducted using actual data. As a result, the correlation shows improvement of 0.4~0.7 and RMSE of about 1~19 cm/s. These high-frequency radar observation results will help solve domestic issues such as response to typhoons, verification of numerical models, utilization of wide area wave data, and ocean search and rescue in the future through the establishment of an open data network.
Numerical Simulation on Reduced Runup Height of Solitary Wave by Fixed Submerged and Floating Rectangular Obstacles
Authors: Shin Choong Hun , Kim Hyung Suk
Published: December 2022

The wave runup height is one of the most important parameters for affecting the design of coastal structures such as dikes, revetments, and breakwaters. In this study, SWASH (Zijlema et al., 2011), a non-hydrostatic pressure numerical model, was used to analyze the effect of reducing The wave runup height of solitary waves by submerged and floating rectangular obstacles. It was confirmed that the SWASH model reproduces the propagation, breaking, and runup of solitary waves quite well. In addition, it was confirmed that the wave deformation of the solitary wave by submerged and floating rectangular obstacles was well reproduced. Finally, we conducted an examination of the effect of reducing the runup height of submerged and floating rectangular obstacles. Reduced runup heights are calculated and the characteristics of runup height reduction according to the dimensions of the obstacle were analyzed. The energy attenuation effect of the floating obstacle is greater than the submerged obstacle, and it is shown to be more effective in reducing the runup height.