bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-term trend analysis of rainfall using hybrid Discrete Wavelet Transform (DWT) based Mann-Kendall tests in central Gujarat region, India
Authors: NIRAV V RAJANI , MUKESH K TIWARI , S S CHINCHORKAR
Published: November 2021

Trend analysis has become one of the most important issues in hydro-meteorological variables study due to climate change and the focus given to it in the recent past from the scientific community. In this study, long-term trends of rainfall are analyzed in eight stations located in semi-arid central Gujarat region, India by considering time series data of 116 years (1901-2016). Discrete wavelet transform (DWT) as a dyadic arrangement of continuous wavelet transformation combined with the widely applied and acknowledged Mann-Kendall (MK) trend analysis method were applied for analysis of trend and dominant periodicities in rainfall time series at monthly, annual and monsoonal time scales. Initially, rainfall time series applied in this study were decomposed using DWT to generate sub-time series at high and low frequencies, before applying the MK trend test. Further, the Sequential Mann-Kendall (SQMK) test was also applied to find out the trend changing points. The result showed that at the monthly annual and monsoon time scales, the trends in rainfall were significantly decreasing in most of the station. The 4-month and 8-month components were found as dominant at the monthly time series and the 2-year and 4-year component were found as dominant at the monsoon time series, whereas the 2-year components were observed as dominant in the annual time scale.
Analysis of precipitation concentration degree changes and its spatial evolution in the western plain of Jilin Province
Authors: RUI ZHANG , AOQI LI , TAOTAO CHEN , GUIMIN XIA , QI WU , DAOCAI CHI
Published: November 2021

In order to study temporal and spatial evolution of the precipitation concentration degree and period in Western Plains of Jilin during the crop growing season and then adjust irrigation strategy, this paper studied the spatial and temporal characteristics of precipitation. Results are as follows: In the growing season from nearly 35 years, the decrease of precipitation during the growing season contributed more to the reduction of interannual precipitation. The maximum precipitation and precipitation duration showed a slight downward trend whereas the minimum precipitation was reversed. Precipitation duration gradually increased from west to east. In the past 35 years, the precipitation concentration degree (PCD) decreased by linear function of “y = -0.0018x + 0.4655”, indicating that the precipitation exhibited a trend of balanced distribution. The PCD decreased from the northwest to the southeast. From the precipitation concentration period (PCP), it changed from early July to late July. In summary, it was important to strengthen the staged drought-preparedness contingency plans in the region.
Bias correction of radar and satellite rainfall estimates and increasing its accuracy using modified merging
Authors: GIARNO GIARNO , MUHAMMAD PROMONO HADI , SLAMET SUPRAYOGI , SIGIT HERUMURTI
Published: November 2021

Bias correction in the weather radar and the tropical rainfall measuring mission (TRMM) rainfall estimates are used to improve its accuracy. This correction is usually done separately for both radar and TRMM. Even though the corrections are done separately, the results of these corrections can be further improved using the merging. Among the methods of merging, modified local bias, mean field bias and conditional merging may be suitable methods used to correct rainfall estimates from remote sensing surrounding in the Makassar Strait. The aim of this research corrects radar and TRMM rainfall estimates, then combining them to obtain more accurate rainfall estimates. The performance will be validated using correlation, root mean square error (RMSE) and mean absolute error (MAE). The result shows that modified mean field bias (Mod_MFB) and local bias (LB) can increase accuracy, mainly RMSE and MAE but not in correlation. However, conditional merging (CM) and modified LB can improve accuracy by increasing correlation and decrease RMSE and MAE. The modification of CM, LB modification and original estimation of remote sensing successively are the order of the best methods. Moreover, merging three data types is not automatically better than merging the two types of data. However, combination 3 types of data offer the stability of accuracy.
Time series analysis on precipitation with missing data using stochastic SARIMA
Authors: M. K. SHARMA , MOHAMMED OMER , SARA KIANI
Published: November 2021

This paper presents an application of the Box-Jenkins methodology for modeling the precipitation in Iran. Linear stochastic model known as multiplicative seasonal ARIMA was used to model the monthly precipitation data for 44 years. Missing data occurred in between for 34 months for some reason. To fill the gap a SARIMA model was fitted based on the first 180 available observations and the missing observations were substituted by the forecasts for the next 34 months. Then a SARIMA model was fitted for the full data. The result showed that the fitted model represent the full data well.
Deslocamento compulsório: relatos de um luto não elaborado
Authors: Pinheiro de Freitas Maria Lívia , Bezerra de Holanda Bessa Renata , Martins Ferreira Karla Patrícia , Arrais Costa Vieira Hélida , Teixeira Mourão Ada Raquel
Published: November 2021

As construções de barragens podem ocasionar à desapropriação de cidades inteiras e realocação de populações. Transformações desta amplitude geram perturbações às comunidades afetadas. Devido a construção da Barragem do Castanhão, a cidade de Jaguaribara foi destruída, e seus moradores transferidos para a primeira cidade projetada do Ceará, a Nova Jaguaribara. Apropriando-se dos conceitos da psicologia ambiental, a pesquisa teve como objetivo compreender aspectos da relação pessoa-ambiente frente ao deslocamento compulsório. Verificou-se na população de Jaguaribara sinais de luto não elaborado, traços de sofrimento psíquico, bem como a fragilização dos vínculos sociais e a redução da autonomia. Compreender as relações humano-ambientais, e impactos decorrentes de processos de deslocamentos programados torna-se primordial para a elaboração de estratégias que visem a redução de danos, potencializem adaptação e a promoção de saúde. Portanto, o impacto da perda do lugar torna-se viabilizador da manifestação e da manutenção de intenso sofrimento favorecendo o surgimento de adoecimentos.
POSTMILENIALISME BERSYARAT: KRITIK TERHADAP ESKATOLOGI PREMILENIALISME DISPENSASIONAL DAN SEBUAH USULAN TERHADAP ESKATOLOGI PENTAKOSTA
Authors: Layantara Jessica
Published: November 2021

So far, Pentecostal eschatology has always been connected with dispensational premillennialist views. But if analyzed, there are actually many things in dispensational premillennialism that are incompatible with Pentecostal theology. This article will briefly explain the history of how Pentecostal eschatology can be influenced by dispensational premillennialism, as well as providing criticisms that prove that this view actually does not correspond essentially with Pentecostal teaching. This article will also try to propose a model of conditional postmillennialism, which is seen as more appropriate to become a framework of Pentecostal eschatology.

 

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Selama ini eskatologi Pentakosta selalu dihubungkan dengan pandangan premilenialisme dispensasional. Namun jika dianalisa, sebenarnya banyak hal di dalam premilenialisme dispensasional yang tidak sesuai dengan teologi Pentakosta. Artikel ini akan menjelaskan secara singkat sejarah bagaimana eskatologi Pentakosta dapat dipengaruhi oleh premilenialisme dispensasional, serta memberikan kritik-kritik yang membuktikan bahwa  pandangan tersebut sebenarnya tidak bersesuaian secara esensial dengan pengajaran Pentakosta. Artikel ini juga akan mencoba mengusulkan sebuah model eskatologi postmilenialisme bersyarat (conditional postmillennialism), yang dipandang lebih sesuai untuk menjadi kerangka eskatologi Pentakosta.
Kristen dan Teknologi: Etika, Literasi dan Ciptaan
Authors: Maurenis Andreas
Published: November 2021

With ethical awareness, literacy abilities, and awareness as God's intelligent creatures, Christians in various dynamics of life must continue to show a human ethics and spirituality, especially in the context of Christian ethics and spirituality. The Christians are able to use the results of the development of science and technology in digital systems. Although, learning, supervision and self-control as God's people are things that are constantly attached to it. With the advance and increasing number of scientific and technological discoveries in various forms, Christians are challenged to publicize themselves and their discipleship calls in the context of digital technology with various media. Christianity and technology become important topics of study that can be included in the umbrella of the great scientific knowledge of theology and science which have been under-attention in certain denominations. Christianity and technology as an academic discourse in lecture classes will be very applicable in the broad life of students and the Christian community in the future, especially by including the ethics, literacy, and creation as sub-topics in it. This discussion has become very important in the age of technology so that understanding and behavior of how Christians should place themselves in the midst of new challenges in the real new age is now being managed with adulthood.

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Dengan kesadaran beretika, kemampuan literasi, dan kesadaran sebagai makhluk ciptaan Tuhan yang cerdas maka umat Kristiani dalam berbagai dinamika hidup mesti tetap memperlihatkan sebuah etika dan spiritualitas manusia, terutama dalam konteks etika dan spiritualitas Kristiani. Umat Kristen terbilang mampu menggunakan hasil perkembangan sains dan teknologi dalam sistem digital. Meskipun pembelajaran, pengawasan dan penguasaan diri sebagai umat Tuhan merupakan hal-hal yang terus-menerus melekat di dalamnya. Majunya dan semakin banyaknya temuan sains dan teknologi dalam berbagai bentuk, membuat umat Kristiani ditantang untuk mempublikasikan diri dan panggilan pemuridannya dalam konteks berteknologi digital dengan berbagai media. Kristen dan teknologi penting menjadi satu pokok bahasan kajian yang bisa dimasukkan ke dalam payung keilmuan besar teologi dan sains yang selama kurang diperhatikan dalam denominasi tertentu. Kristen dan teknologi sebagai satu diskursus akademik di dalam kelas-kelas perkuliahan akan menjadi sangat aplikatif dalam kehidupan luas mahasiswa dan masyarakat Kristiani di kemudian hari apalagi dengan menyertakan sisi etika, literasi, dan ciptaan sebagai sub-sub bahasan di dalamnya. Pembahasan ini  menjadi amat penting di zaman teknologi agar pemahaman dan perilaku bagaimana seharusnya umat Kristiani menempatkan dirinya di tengah-tengah tantangan baru di zaman baru yang nyata sekarang ini menjadi terkelola dengan dewasa.
Analisis dan Perancangan Sistem Informasi Manajemen Sumberdaya Manusia dengan Metode Analisis Pieces (Studi Kasus pada PT. Asuransi)
Authors: Halim Ridwan
Published: November 2021

PT. Asuransi mengalami pertumbuhan usaha cukup pesat dan sejalan dengan meningkatnya aktifitas usaha dibutuhkan pengelolaan tenaga kerja yang efektif dan efisien. Seiring dengan perkembangan dunia yang terus berubah dimana kehidupan dan teknologi baru terus dikembangkan. Perubahan ini mengharuskan pemimpin organisasi menyadari berbagai jenis teknologi yang dapat meningkatkan efektivitas organisasi.  Penelitian ini menganalisis sistem lama yang diterapkan bagian SDM PT Asuransi yang masih menggunakan formulir dan pemberkasan secara paper based. Dengan menggunakan analisis berbagai variabel metode PIECES menemukan kelebihan dan kekurangan sistem lama dan merancang sistem baru dengan ruang lingkup menu, proses, database dan interface dengan menggunakan unified modeling language. Dari penelitian yang telah dilakukan dengan metode kuesioner serta wawancara hasil penelitian baik karyawan maupun manajemen berpendapat sistem yang ada sat ini sudah tidak lagi dapat menunjang aktifitas pengelolaan sumber daya manusia. Disertai dengan analisis pada flowchart sistem lama yang digunakan bagian SDM PT Asuransi bersifat prosedural manual dengan paper based sistem pengelolaan manajemen sumber daya manusia pada PT Asuransi. Hasil dari penelitian ini diharapkan agar dapat digunakan sebagai bahan referensi manajemen PT Asuransi untuk pengelolaan sumber daya manusia yang lebih baik.
Validitas Perangkat Pembelajaran Penanganan dan Perawatan Cidera (PPC) “Lo,i ncara ro mpoka” menggunakan Hellison’s Model untuk mengembangkan Kreativitas Mahasiswa
Authors: Fauqi Amal
Published: November 2021

Penelitian Ini Validitas Perangkat Pembelajaran Penanganan dan Perawatan Cidera (PPC) “lo,i ncara ro mpoka” menggunakan Hellison’s Model untuk mengembangkan kreativitas mahasiswa. merupakan beberapa upaya untuk mengajarkan Mahsiswa untuk dapat mengambil sikap serta melatih kemampuan berpikir kreatif mahasiswa Program Studi Penjaskesrek STKIP Yapis Dompu dalam mengambil peran menangani cedera sekaligus melestarikan khasanah budaya  daerah masyarakat dompu NTB. Penelitian ini adalah penelitian pengembangan dengan menggunakan model 4-d. Adapun Simpulan yang diperoleh dari penilitian ini adalah nilai komulatif dua validator terhadap seluruh komponen perangkat pembelajaran yang dikembangkan berada pada kategori sangat valid dengan skor 3,6. Rincian  4 komponen perangkat yang dinilai antara lain: RPS dengan skor 3,8/ sangat valid, LKM dengan skor 3,3/valid, Buku ajar dengan skor 3,5/valid, Tes KBK dengan skor 3,7/sangat valid. Dengan demikian seluruh komponen perangkat pembelajaran yang telah dikembangkan layak untuk diujicobakan.
Pengaruh Kompetensi Profesional Terhadap Motivasi Kerja Guru SD di Gugus Rujakbeling Kecamatan Kebumen Kabupaten Kebumen
Authors: Faridah Ida
Published: November 2021

Penelitian ini bertujuan menganalisis pengaruh kompetensi profesional terhadap motivasi kerja guru SD di Gugus Rujakbeling Kecamatan Kebumen Kabupaten Kebumen. Jumlah populasi sebesar 41 guru dan sampel yang digunakan adalah 41 seluruh populasi dijadikan sebagai sampel penelitian, sehingga dapat dikatakan bahwa penelitian ini adalah penelitian populasi. Pengumpulan data dilakukan dengan metode angket. Uji validitas dengan teknik analisis Product Moment dan uji reliabilitas menggunakan Alpha Cronbach. Uji persyaratan analisis data menggunakan uji normalitas, linearitas. Pengujian hipotesis menggunakan uji regresi sederhana Hasil penelitian ini menunjukkan: Terdapat pengaruh pengaruh kompetensi profesional terhadap motivasi kerja guru SD di Gugus Rujakbeling Kecamatan Kebumen Kabupaten Kebumen dengan t hitung > dari t tabel (2,611 > 2,023) dan besarnya pengaruhnya sebesar 14,9% diketahui dari R Square sebesar 0,149.
Razlike u testovima koordinacije učenika petih razreda oš Kraljevica – učenika matične škole koji izvode nastavu tjelesne i zdravstvene kulture u sportskoj dvorani i učenika područnih škola koje nemaju sportsku dvoranu
Authors: Juriša Davor , Vučković Sunčica
Published: November 2021

Koordinacija ima svoje zakonitosti razvoja kroz određeno vremensko razdoblje rasta i razvoja djece. U tom vremenskom razdoblju može se upravljanim procesom vježbanja utjecati na poboljšanje koordinacije. Ukoliko se to učini, djeca će u istim uvjetima rada
bolje napredovati i tijekom narednog dužeg vremenskog razdoblja. Cilj ovog rada
je pokazati razlike u napredovanju dviju grupa učenika s početnim različitim
uvjetima rada.
Studi Apologetika Tentang Pandangan Rasul Paulus Terhadap Kepemimpinan Wanita Di Gereja
Authors: Abraham Jessica Elizabeth
Published: November 2021

Paul’s theological view on women in church leadership is often misinterpreted if not misunderstood. It is true that at first glance, his prohibitions and policies for women sound degrading the women’s role. Yet, the application of the appropriate hermeneutical approach to his writings such as in 1 Corinths 11:2-16, 1 Corinths 14:34-35 and 1 Timothy 2:9-14 will show that Paul is never against women leading the church. This writing hopes to expand the church’s perspective on women’s leadership so that the church can provide women with the same opportunity as for the men in building up the body of Christ. On the other hand, it hopes to empower more women to take on leadership roles in the church without hesitation. [Pandangan teologis Rasul Paulus terhadap kepemimpinan wanita di gereja seringkali diterjemahkan dengan keliru atau disalah pahami. Jika dilihat secara sekilas, larangan dan aturan yang ia berikan kepada wanita terdengar merendahkan mereka. Namun, penerapan pendekatan hermeneutika yang sesuai dengan tulisan-tulisannya seperti dalam 1 Korintus 11:2-16, 1 Korintus 14:34-35 dan 1 Timotius 2:9-14 akan menunjukkan bahwa Rasul Paulus tidak pernah menentang wanita untuk memegang jabatan kepemimpinan di gereja. Tulisan ini diharapkan dapat memperluas perspektif gereja tentang kepemimpinan wanita sehingga wanita dapat memiliki kesempatan yang sama layaknya pria dalam membangun tubuh Kristus. Di sisi lain, gereja juga diharapkan untuk dapat memberdayakan lebih banyak lagi wanita untuk mengambil peran dalam kepemimpinan gereja tanpa ragu.]
Pembentukan Karakter Pemimpin Kristen Yang Unggul Di Era Milenial
Authors: Thobias Apriati Woi Sawanen
Published: November 2021

AbstractThe development of increasingly advanced technology has influenced the lives of believers, one of which is gadgets. Gadgets are a daily necessity and even a basic necessity. This development is very good. However, not all of these developments must be followed. Even Christian youths are involved in the alcohol trend. This is not a good situation. Christian leaders need to see and anticipate this so that the congregation does not carry on with the flow of developments that will distract people from the life that should be an example for their surroundings. The method used by the author is a qualitative method. Qualitative Method because of the problem regarding the decline of Christian leadership in the Millennial Era. In this era, Christian leaders who are superior in character are needed. Not a few of Christian leaders do not care about their character. This requires the willingness of Christian leaders who want to build their character so that they become superior and capable Christian leaders. Because without good character, leaders are unable to lead. Character is the main thing that is prepared by Christian leaders to become leaders. Perkembangan teknologi yang makin maju ini telah mempengaruhi kehidupan orang percaya, salah satunya adalah gadget. Gadget menjadi kebutuhan sehari-hari bahkan menjadi kebutuhan pokok. Perkembangan ini sangat baik. Namun tidak semua perkembangan itu harus diikuti. Bahkan ada anak-anak muda Kristen pun terlibat dalam tren miras. Ini merupakan keadaan yang tidak baik. Pemimpin Kristen perlu melihat dan mengantisipasi hal ini agar jemaat tidak berbawa arus perkembangan yang akan menjauhkan mereska dari kehidupan yang harusnya menjadi teladan bagi sekitarnya. Metode yang digunakan oleh penulis adalah metode kualitatif. Metode Kualitatif karena persoalannya mengenai kemerosotan kepemimpinan Kristen di Era Millenial. Di Era ini sangat diperlukan pemimpin Kristen yang unggul dalam karakternya. Tidak sedikit dari pemimpin Kristen tidak peduli akan karakternya. Untuk itu diperlukan kesediaan pemimpin Kristen yang mau dibangun karakternya agar menjadi pemimpin Kristen yang unggul dan mampu memimpin. Sebab tanpa karakter yang baik, pemimpin tidak mampu memimpin. Karakterlah yang utama dipersiapkan pemimpin Kristen untuk menjadi pemimpin.
Determinants of Capital Adequacy Ratio of Banks in Botswana
Authors: Kablay Hassan , Gumbo Victor
Published: November 2021

Capital Adequacy Ratio (CAR) plays a very important role in the financial success of banks and acts as a buffer to prevent and absorb any unexpected losses. This study examines explanatory variables that influence CAR for nine banks in Botswana. Multiple linear regression was used for analysis, with CAR as the dependent variable and thirteen financial ratios as the independent variables. The study period is 2015-2019. Based on the data for this period, it was established that out of the thirteen financial ratios utilised, only four were found to have significant impact on the CAR of the nine banks under study, which are: Asset to Equity Ratio (A E), Return on Equity (ROE), Non-Performing Loans Ratio (NPL RATIO) and the Cost-to-Income Ratio (C I). The A E Ratio was found to be the most influential driver of the CAR and the NPL Ratio was found to be the least influential driver of the CAR for the banks under study.
Soziologie der Geschlechterkritik
Authors: Hutzler Michael
Published: November 2021

This case study examines queer–feminist critique of gender differences and asks how gender categorisation is handled in this critical practice. Conceptually, the study develops the perspective of the sociology of gender critique, in which both traditional gender arrangements and critique of them are understood as contingent social phenomena. The fact that the investigation in this case encounters a field strongly shaped by academic discourse is taken as an opportunity to reflect on academic knowledge production: How do gender-critical practices inside and outside academia co-produce the very phenomena they criticise?
Dichtung der augusteischen Epoche und der frühen Kaiserzeit
Authors: Holzberg Niklas
Published: November 2021

Niklas Holzberg, who until his retirement in 2011 was a professor of Classics at the University of Munich, of-fers a collection of twenty-three papers on Roman poetry of the Augustan age and the early imperial era. Published between 1997 and 2019 in periodicals and anthologies, fifteen of them were originally written in English or Italian and are published here in German for the first time. They discuss works by Virgil, Horace, Ovid, the elegists, Martial, Ps.-Virgil, Ps.-Tibullus and Ps.-Seneca. The interpretations of the texts focus on self-reflection as expressed by intertextuality and implicit metapoetics, sequential reading of poetry books and the recognition of pseudepigraphs as literary games played by anonymous authors impersonating classical poets.
Pain Control After Mastectomy in Transgender Patients: Ultrasound-guided Pectoral Nerve Block II Versus Conventional Intercostal Nerve Block: A Randomized Clinical Trial
Authors: Rokhtabnak Faranak , Sayad Soheila , Izadi Maryam , Djalali Motlagh Soudabeh , Rahimzadeh Poupak
Published: November 2021

Background: Mastectomy is sometimes performed in transgender patients, which may damage the regional nerves such as the pectoral and intercostobrachial nerves, leading to postoperative pain. An ultrasound-guided nerve block can be used to track and block the nerves properly. Objectives: This study aimed to compare the ultrasound-guided type-II pectoral nerve block with the blind (conventional) intercostal nerve block (ICNB) for pain control after breast tissue reconstruction surgery in transgender patients. Methods: In the present single-blind randomized clinical trial, 47 patients were randomly divided into two groups: (A) Ultrasound-guided type-II pectoral nerve block (n = 23) and (B) blind intercostal nerve block (n = 24). After nerve block in both groups, pain intensity at 3, 6, 12, and 24 hours after surgery, upper limb paresthesia, frequency of nausea and vomiting, shortness of breath, hematoma, and the length of hospital stay were assessed. Results: Patients who received the ultrasound-guided type-II pectoral nerve block had a greater reduction in pain intensity (24 h after surgery), opioid use (24 h after surgery), nausea, vomiting, and hospital stay than those who received ICNB, whereas the recovery time did not differ between the study groups. Conclusions: The pectoral nerve block under ultrasound guidance, compared to the intercostal nerve block, in transgender patients can reduce the required dosage of opioids within 24 hours, pain intensity within 24 hours after surgery, the incidence of postoperative nausea, and vomiting, and the hospital stay of patients.
Quantification of the Brain MS Plaque Volume: Comparison of Quantitative and Qualitative Estimation of the Brain MS Plaque Volume in Successive MRI Before and After Medication Use
Authors: Abolhasani Foroughi Amin , Zeinali-Rafsanjani Banafsheh , Nazeri Masoume , Saeedi-Moghadam Mahdi , Torkaman Amir
Published: November 2021

Background: Multiple sclerosis (MS) is a demyelinating disease with multiple symptoms. To examine the effect of medications, magnetic resonance imaging (MRI) imaging can be performed. Objectives: This study aimed to compare the visual assessment of MRI images by physicians and the results of a MATLAB-based software developed for evaluating the MS plaque volume. Patients and Methods: TYSABRI (natalizumab)-treated patients were enrolled in this study. MRI was performed before and after treatment. A MATLAB-based software was developed to evaluate the MRI images. The images were then subjectively evaluated by three specialists and objectively assessed by the software, and the results were then compared. Results: Thirty-five patients participated in this study. According to the software, the status of 37.14% of the patients improved; however, 62.86% of cases deteriorated after a year of treatment. There was less than 50% agreement between the physicians and less than 55% agreement between the physicians and the software results. A disagreement of almost 45% was observed between the physicians and the software results, as in some cases, small changes were detected in successive images. The second cause of disagreement could be the physicians’ expectations; although the patient’s recovery was highly expected in some cases, their condition deteriorated. Conclusion: The results revealed that the objective assessment of sequential MRI images of MS patients reduced human errors and improved the evaluation of this disease.
Impact of Short-Incubation MALDI-TOF MS on Rapid Identification of Pathogens and Antibiotic Therapy
Authors: Chen Qianqian , Zhang Anran , Kong Haifang , Hu Zhidong
Published: November 2021

Background: It can be a critical point for reducing pathogen identification time and accurate antibiotic treatment for patients with blood circulation infection since it causes high mortality. Objective: The objectives of this study were to evaluate the time differences between conventional identification and MALDI-TOF conventional identification and short-incubation MALDI-TOF identification for positive blood cultures, and to explore the impact of short-incubation matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS) identification on empirical antibiotic therapy. Methods: Positive blood cultures were collected in our hospital from 2017 to 2019, clinical data were collected from the medical records, which were analyzed retrospectively to determine the empirical antibiotic therapy. Results: Compared with the conventional identification method, the short-incubation MALDI-TOF identification time to initial identification of Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, Staphylococcus aureus, Enterococcus faecium, and E. faecalis decreased by 22.28 h, 22 h, 23.59 h, 23.63 h, 22.63 h, 23.92 h, and 21.59 h, respectively (P < 0.05). The time to final reporting was decreased by 48.85 h, 47.99 h, 55.40 h, 51.07 h, 49.60 h, 51.78h, and 51.73h, respectively (P < 0.05). However, the antimicrobial susceptibility test time of E. coli, A. baumannii, and S. aureus increased to 2.02 h, 2.19 h, and 3.86 h, respectively (P < 0.05). The coincidence rate of antimicrobial susceptibility was 98.48% between short-incubation MALDI-TOF identification and conventional identification method of all Gram-negative bacilli, and there were no extremely major errors or major errors. The coincidence rate of antimicrobial susceptibility of Gram-positive cocci was 99.53%, one strain of E. faecium and S. aureus had major errors. Patients received earlier correct empirical antibiotic 19.89 h earlier by short-incubation MALDI-TOF identification than the conventional identification method (P < 0.001). Conclusions: The short-incubation MALDI-TOF identification significantly shortens the pathogen identification time and the final report time, it is a reliable method for rapid identification of positive blood cultures; the results of antimicrobial susceptibility are highly consistent, which significantly lead to earlier appropriate empirical therapy of bacteremia.
Barevný test cesty pro děti: Recenze metody
Authors: Sedláčková Pavla , Galbavá Simona
Published: November 2021

Barevný test cesty pro děti je screeningovou metodou určenou pro měření pozornosti dětí ve věku od 5 do 7 let. Test lze využít také jako součást diagnostiky školní zralosti. Kromě pozornosti lze usuzovat rovněž na vizuálně prostorovou orientaci dítěte. Jedná se o novou metodu vyvinutou v České republice, která je inspirována široce užívanou neuropsychologickou metodou Test cesty (Trail Making Test; TMT). Informace poskytnuté k validitě a reliabilitě hodnotíme jako adekvátní, nicméně k těmto oblastem by dle našeho názoru bylo vhodné doplnit více důkazů. Barevný test cesty pro děti je podle nás vhodným nástrojem pro zamýšlené účely, avšak nízký skór v testu nelze s aktuálními normami nijak blíže interpretovat a měl by tedy sloužit pouze jako doporučení pro komplexnější diagnostiku pozornosti.
Test pozornosti d2-R – Recenze metody
Authors: Azzamová Katarína
Published: November 2021

Aktuálna revidovaná verzia testu d2 je nepochybne zlepšením oproti verzií pôvodnej, recenzovanej Gabrhelom (2014) a Krausom (2015). Zvýšením počtu znakov na jeden riadok zo 47 na 57 sa podarilo vyhnúť efektu stropu a priniesť tak viac informácií o skúmaných osobách. Rovnako je potrebné oceniť skrátené a zrozumiteľnejšie inštrukcie, ktoré sa pravdepodobne prejavili v menšej chybovosti z dôvodu neporozumenia. Nová verzia tiež priniesla zjednodušené vyhodnotenie, vďaka ktorému je rovnako možné vyhnúť sa chybám na strane administrátora a v neposlednom rade rozšírila príručku o dôležité informácie o validite, vývoji testu a jej súčasťou je množstvo odkazov na výskumné štúdie. Vo všeobecnosti ale ide o použiteľnú metódu, s vysokou reliabilitou a s dostatočne veľkou štandardizačnou vzorkou (N = 4024). Jej výsledky je však potrebné brať vzhľadom k uvedeným nevýhodám s rezervou a údaje prípadne doplniť z iných zdrojov, z ktorých je možné získať informácie o selektivite a koncentrácií pozornosti.
L’organització dels textos en els llibres de poesia de Joan Maragall
Authors: Moreta Ignasi
Published: November 2021

L’article estudia els elements paratextuals que acompanyen l’obra poètica de Maragall publicada en forma de llibre a fi d’esclarir la manera com l’autor organitza l’arquitectura dels seus llibres. La inclusió dels seus poemes en els llibres de poesia que publica, la seva disposició en l’arquitectura dels llibres, l’organització (seccions, portadelles, recursos tipogràfics emprats, índexs, etc.), les continuïtats i discontinuïtats entre els seus llibres, són elements que ens parlen de com Maragall vol ser llegit. Maragall construeix els seus llibres amb plena consciència i amb una gran professionalitat, organitzant-los de manera pensada i sofisticada.
No bicentenario do nacemento de Marcial Valladares: unha cronoloxía da súa biobibliografía
Authors: Fernández Salgado Xosé A.
Published: November 2021

Este traballo quere conmemorar o bicentenario do nacemento de Marcial Valladares (1821-1903), un autor fundamental do Rexurdimento galego que se distingue por unha obra pioneira, prolífica e poliédrica que conxuga o literario, o lingüístico e o folclórico. Con este obxectivo, realizamos un relato cronolóxico da súa biobibliografía, resultado de revisar, sistematizar e harmonizar os datos de traballos xa existentes sobre o escritor e lingüista e doutros novos procedentes do rastrexo feito nas páxinas da prensa do século XIX e XX.
NOR-CAM – A framework for assessment of academic careers in the Open Science Era
Authors: Johansen Finn-Eirik
Published: November 2021

See RECORDING.
A working group appointed by Universities Norway (UHR) was mandated to recommend guiding principles for the assessment and evaluation of research(ers) in light of the transition to Open Science. In February 2021 the working group delivered their report, which includes a guide for research assessment. Johansen will give a brief introduction to NOR-CAM.
A small molecule targeting CHI3L1 inhibits lung metastasis by blocking IL‐13Rα2‐mediated JNK‐AP‐1 signals
Authors: Lee Yong Sun , Yu Ji Eun , Kim Ki Cheon , Lee Dong Hun , Son Dong Ju , Lee Hee Pom , Jung Jae‐kyung , Kim Nam Du , Ham Young Wan , Yun Jaesuk , Han Sang‐Bae , Hong Jin Tae
Published: November 2021

Our previous big data analyses showed a high level of association between chitinase 3 like1 (CHI3L1) expression and lung tumor development. In the present study, we investigated whether a CHI3L1‐inhibiting chemical, 2‐({3‐[2‐(1‐cyclohexen‐1‐yl)ethyl]‐6,7‐dimethoxy‐4‐oxo‐3,4‐dihydro‐2‐quinazolinyl}sulfanyl)‐N‐(4‐ethylphenyl)butanamide (K284), could inhibit lung metastasis and studied its mechanism of action. We investigated the antitumor effect of K284 both in vitro and in vivo. K284 (0.5 mg·kg−1 body weight) significantly inhibited lung metastasis in in vivo models after injection of murine melanoma cells (B16F10) or adenocarcinomic human alveolar basal epithelial cells (A549). K284 significantly and concentration‐dependently also inhibited cancer cell proliferation and migration in the A549 and H460 lung cancer cell lines. We found that the binding of K284 to the chitin‐binding domain (CBD) of CHI3L1 prevented the binding of CHI3L1 to its receptor, interleukin‐13 receptor subunit alpha‐2 (IL‐13Rα2), thereby suppressing the CHI3L1 signal. This blocking of the CHI3L1‐IL‐13Rα2 signal caused the inhibition of c‐Jun N‐terminal kinase (JNK)‐activator protein 1 (AP‐1) signals, resulting in the prevention of lung metastasis and cancer cell growth. Our data demonstrate that K284 may serve as a potential candidate anticancer compound targeting CHI3L1.
Adaptive quantized tracking control for a class of uncertain nonlinear systems
Authors: Su Hang , Zhang Weihai , Zhang Xuepeng
Published: November 2021

In this article, we propose a new effective adaptive tracking control scheme for a class of uncertain nonlinear systems with unknown functions and disturbances. In the considered system, the control signal is quantized by an asymmetric hysteresis quantizer. By introducing the nonlinear decomposition of the quantized input and a novel transformation of the control signal, the obstacle caused by input quantization is successfully overcome, and a coarse quantization can be obtained. The developed control method can guarantee that the signals of the closed‐loop system are bounded, and the tracking error converges to a small neighborhood of the origin. Finally, simulation results not only illustrate how to select the relevant parameters, but also demonstrate the effectiveness of the designed control approach.
Pressure‐Tailored Band Engineering for Significant Enhancements in the Photoelectric Performance of CsI3 in the Optical Communication Waveband
Authors: Li Zonglun , Li Quanjun , Li Haiyan , Yue Lei , Zhao Dianlong , Tian Fuyu , Dong Qing , Zhang Xueting , Jin Xilian , Zhang Lijun , Liu Ran , Liu Bingbing
Published: November 2021

The bandgap and type of optical transition are key factors in determining the functionalities and applications of photoelectric materials. However, it is extremely difficult to modulate the bandgap and indirect‐direct bandgap transition for most materials. This study reports significant enhancements in photocurrents and an extended detection bandwidth resulting from pressure‐regulated indirect–direct bandgap transition in hypervalent CsI3. Furthermore, this study achieves an increase in the photocurrent by almost five orders of magnitude under visible‐light illumination. Impressively, the detection band‐edge shows a successive redshift from visible light to 1650 nm (optical communication waveband) upon compression. And high pressure is conducive to CsI3 operating at an ultralow bias input. Extensive high‐pressure spectroscopy analyses and theoretical calculations suggest that changes in the photoelectric properties of CsI3 are associated with enhanced I–I interactions along the quasi‐endless linear chain directions under compression. These findings offer an effective band engineering strategy for achieving broadband spectral response and high gains with an ultralow bias in photoelectric detectors.
Ultrafast‐Response/Recovery Flexible Piezoresistive Sensors with DNA‐Like Double Helix Yarns for Epidermal Pulse Monitoring
Authors: Chen Jianming , Zhang Jun , Hu Jinlian , Luo Ningqi , Sun Fengxin , Venkatesan Harun , Zhao Ni , Zhang Yuanting
Published: November 2021

A key challenge in textile sensors is to adequately solve the hysteresis for more broad and exacting applications. Unlike the conventional strategy in integrating elastic polymers into the textile, the hysteretic issue is critically addressed here through the structural design of yarns to provide a twisting force. The underlying mechanism is fully discussed based on theory and modeling, which are in good agreement with experimental data. Impressively, the pressure sensor outperforms almost all reported textile‐based sensors in terms of recovery index, which refers to the ability to overcome the lagged deformation reflected by the hysteresis (5.3%) and relaxation time (2 ms). Besides, the sensor superiority is also demonstrated by way of its ultrafast response time (2 ms). Thanks to these merits, this pressure sensor is demonstrated to be capable of monitoring epidermal pulses and meanwhile shows great potential to advance the standardization and modernization of pulse palpation in traditional Chinese medicine.
Bio‐inspired Synthesis of Energetic Microcapsules Core‐Shell Structured with Improved Thermal Stability and Reduced Sensitivity via In Situ Polymerization for Application Potential in Propellants
Authors: Chen Ling , Li Qiang , Liu Shishuo , Bei Yiying , Ding Yajun , Liu Jie , He Weidong
Published: November 2021

To further improve the comprehensive performances of conventional nitramine energetic crystals hexahydro‐1,3,5‐trinitro‐1,3,5‐triazine (RDX), 1,3,5,7‐tetranitro‐1,3,5,7‐tetrazocane (HMX), and 2,4,6,8,10,12‐hexanitro‐2,4,6,8,10,12‐hexaazaisowurtzitane (CL‐20), especially their thermal stability and safety properties, is the main pursue in the field of energetic materials. Enlightened by means of the composition of attachment proteins from mussels, this research demonstrates that polydopamine (PDA) self‐polymerization could be used to prepare core‐shell structure energetic composites by surface coating technology. The results reveal that energetic crystal cores are mostly well‐coated by PDA more than 6 h; the combined characteristics of explosives and PDA indicating the main interface interaction force is hydrogen bonding. Moreover, the optimal polymorph of HMX (β) and CL‐20(ε) are maintained in the preparation process. Besides, another interesting phenomenon can be observed that the polycrystalline phase transition of endothermic and the decomposition temperature of exothermic peak for energetic crystals have been increased evidently, benefitting from the heat resisting of PDA layer. Moreover, thermal decomposition has been studied and calculated under different heating rates. Furthermore, the impact sensitivity of the PDA modified composites obtained is tested as well and decreased by 2–4 times compared with pristine energetic crystals. Therefore, this fabrication strategy in this study would provide a potential application of energetic@PDA in high‐strength and high‐energy propellants.
Measurement and Modeling of the Nanofiber Surface Potential during Electrospinning on a Patterned Collector: Toward Directed 3D Microstructuration
Authors: Liang Meng , Hébraud Anne , Sutter Christophe , Bardin Antoine , Lobry Emeline , Schlatter Guy
Published: November 2021

Electrospinning allows the fabrication of microstructured mats when the nanofiber is deposited on a patterned collector made of regularly distributed protuberances. Such directed self‐assembling strategy results from the building of an electrostatic template induced by the charged deposited fiber strands suspended between the protuberances which in turn induces a field of attractive and repulsive forces that guide the deposition of the fiber during its landing. However, after a certain time of electrospinning, the microstructuration of the mat is generally subjected to modification and is eventually lost. Here, it is shown that the measurement of the surface potential above the deposited nanofibers is a powerful tool to track the evolution of the fibrous microstructuration during the fabrication. First, the electrospinning above a single and adjustable gap is deeply investigated and a model is proposed to explain the surface potential kinetics as a function of the gap size and the processed polymer solution. Then, the surface potential kinetics are correlated with the evolution of the 3D microstructuration in the case of electrospinning on a micropatterned collector. This original strategy paves the way for the controlled fabrication of 3D microstructured mats dedicated to a wide range of applications.
Hierarchically Structured Ni‐Enhanced Flexible Multiwall Carbon Nanotubes/Polydimethylsiloxane for a High‐Performance Pressure Sensor
Authors: Bai Yao‐Yao , Zhang Bin , Wu Xu‐Ping , Luo Yan‐Wen , Bai Zeng‐Guo , Wang Si‐Qi , Zhang Guang‐Ping
Published: November 2021

Flexible pressure sensors have given rise to great research interest because of their potential applications in artificial electronic skin, wearable health‐care monitors, soft robotics, and hydrophones. However, determining how to fabricate a sensor with high sensitivity in a wide linear range by using a simple and cost‐effective manufacturing method remains a challenge. Here, a novel pressure sensor composed of a flexible substrate of multiwall carbon nanotubes (MWCNTs)/polydimethylsiloxane (PDMS) covered with a hierarchically structured Ni layer consisting of large amounts of nanoneedles and some irregular microspherical aggregates is presented. Owing to the synergistic effect of the hierarchically structured Ni layer and the special deformation behavior of the flexible MWCNTs/PDMS substrate, the as‐fabricated sensor has a high sensitivity of 10.7 kPa−1 in a wide linear range up to 15 kPa, keeping stability after 2.5 × 103 repeatedly compressing–releasing cycles. The sensor demonstrates sensitivity in monitoring both weak vibrations and human joint motions, which may have great potential in the field of health monitoring and electronic skin.
Computer vision and machine‐learning techniques for quantification and predictive modeling of intracellular anticancer drug delivery by nanocarriers
Authors: Goswami Sanjay , Dhobale Kshama D. , Wavhale Ravindra D. , Goswami Barnali , Banerjee Shashwat S.
Published: November 2021

The field of cancer nanomedicine has made significant progress, but its clinical translation is impeded by many challenges, such as the difficulty in analyzing intracellular anticancer drug release by the nanocarriers due to the lack of suitable tools. Here, we propose the development of an image‐based strategy involving machine learning (ML) to evaluate anticancer drug such as doxorubicin hydrochloride (DOX) released by a nanocarrier inside the HCT116 colon cancer cells and its subsequent intracellular accumulation. This technique combines fluorescent cell imaging with ML‐based image analysis to assess and quantify the delivery of DOX by nanoparticles within them. We show that DOX in HCT116 cells was higher for multifunctional CNT‐DOX‐Fe3O4 nanocarrier than free DOX, indicating efficient and steady release of DOX as well as superior retentive property of the nanocarrier. Initially (1 and 4 hours), the luminance intensity of DOX in the cell cytoplasm delivered by CNT‐DOX‐Fe3O4 nanocarrier was ~0.34 and ~0.42 times lesser than that of free DOX delivered normally. However, at 24 and 48 hours posttreatment, the luminance intensity of DOX for CNT‐DOX‐Fe3O4 nanocarrier was ~1.98 and ~1.92 times higher than that of free DOX. Furthermore, the luminance intensity of DOX for CNT‐DOX‐Fe3O4 in the whole cell was ~1.35 and ~1.62 times higher than that of free DOX at 24 and 48 hours, respectively. The high‐throughput nature of our image analysis workflow allowed us to automate the process of DOX retention analysis and enabled us to devise ML‐based modeling to predict the percentage of anticancer drug retention in cells. The development of models to automatically quantify and predict intracellular drug release in cancer cells could benefit personalized treatments by optimizing the design of nanocarriers.
Inter‐individual variability in children's physical growth and body composition: Findings of longitudinal ELOS‐Pré study
Authors: de Jesus Sousa Lima Teresinha , dos Prazeres Thaliane Mayara Pessôa , dos Santos Henrique Rafael , da Rocha Queiroz Daniel , Bezerra Jorge , de Barros Mauro Virgílio Gomes , dos Santos Marcos André Moura
Published: November 2021

Background

Children's physical growth (PG) and body composition (BC) can be influenced by birth weight and type of delivery.

Aim

To longitudinally analyze the dynamics of PG and BC of children from 5 to 9 years; to investigate the inter‐individual differences according to age, sex, BW, and type of delivery across the following years of the study.

Subjects and methods

A total of 1236 children (597 boys) were evaluated at 5‐years of age and followed annually until 9‐years. PG and BC measurements were evaluated. Multilevel modeling was used.

Results

Annual increments were observed (p < .001). Girls presented lower height and fat‐free‐mass but higher %BF (p < .001). Distinct trajectories between the sexes were observed for height (p < .001). Low‐birth‐weight children presented lower height, body mass, and fat‐free‐mass (p < .001), but the interaction between velocity of growth and BC was significant only in height (p < .05). Children born by had lower height, body mass, and %BF, and gained less body mass per year than those born by vaginal delivery (p < .05). Significant inter‐individual differences were observed at 5‐years of age and in their trajectories, except for fat‐free‐mass (p < .01).

Conclusion

There are differences in the dynamics of PG and BC, low‐birth‐weight and type of delivery influence the dynamics of PG during this interval of ages.
Predictive value of ATN biomarker profiles in estimating disease progression in Alzheimer's disease dementia
Authors: Ezzati Ali , Abdulkadir Ahmed , Jack Clifford R. , Thompson Paul M. , Harvey Danielle J. , Truelove‐Hill Monica , Sreepada Lasya P. , Davatzikos Christos ,   the Alzheimer's Disease Neuroimaging Initiative, Lipton Richard B.
Published: November 2021

We aimed to evaluate the value of ATN biomarker classification system (amyloid beta [A], pathologic tau [T], and neurodegeneration [N]) for predicting conversion from mild cognitive impairment (MCI) to dementia. In a sample of people with MCI (n = 415) we assessed predictive performance of ATN classification using empirical knowledge‐based cut‐offs for each component of ATN and compared it to two data‐driven approaches, logistic regression and RUSBoost machine learning classifiers, which used continuous clinical or biomarker scores. In data‐driven approaches, we identified ATN features that distinguish normals from individuals with dementia and used them to classify persons with MCI into dementia‐like and normal groups. Both data‐driven classification methods performed better than the empirical cut‐offs for ATN biomarkers in predicting conversion to dementia. Classifiers that used clinical features performed as well as classifiers that used ATN biomarkers for prediction of progression to dementia. We discuss that data‐driven modeling approaches can improve our ability to predict disease progression and might have implications in future clinical trials.