bluuebunny/crossref_metadata_2025 huggingface dataset:
The Varieties of (Un)Boundedness
Authors: Roelofs Luke
Published: October 2024

I analyse six different senses in which a conscious mind can be said to be either 'bounded' or 'unbounded', and evaluate how well they might capture what people mean when they say either that human consciousness is necessarily bounded, that it introspectively appears bounded, or that
mystical and psychedelic experiences remove its apparent boundedness. I then argue that, although human consciousness is certainly bounded in one important sense (informational boundedness), this does not entail that it is phenomenally bounded, in the sense of being divided into separate fields
of experience. In fact, if panpsychists are right that consciousness is fundamental and nature is uniform, it is likely that human consciousness is phenomenally unbounded: the whole universe is likely to be a single field of consciousness, with each of us being an informationally dense region
of it. I close by noting some ways that this claim of phenomenal unboundedness ('continuism') impacts debates among panpsychists about how to solve the combination problem.
Does Panpsychism Mean That 'We Are All One'?
Authors: Mørch Hedda Hassel
Published: October 2024

Panpsychism is the view that all things are associated with consciousness. Panpsychism has a number of significant theoretical implications, with respect to the mind–body problem and other problems in metaphysics. Here I will consider one of its potential practical or ethical
implications; specifically, whether, if panpsychism is true, it follows that 'we are all one', in a sense that implies that egoism (understood as bias towards what we normally take to constitute the self or ego) is not only immoral but fundamentally irrational (or imprudent).
Atlas Afrodescendiente: Territorios ancestrales y tierras colectivas Afrodescendientes en América Latina y el Caribe
Authors:   Rights and Resources Initiative,   Proceso de Comunidades Negras,   Coordenação Nacional de Articulação das Comunidades Negras Rurais Quilombolas,   Observatorio de Territorios Étnicos y Campesinos
Published: October 2024

Este Atlas sobre los territorios ancestrales, asentamientos rurales y las tierras de propiedad colectiva de los Pueblos Afrodescendientes en América Latina, es producto de un trabajo entre organizaciones del movimiento social Afrodescendiente de las Américas, la Iniciativa para los Derechos y Recursos (RRI por sus siglas en inglés), el Proceso de Comunidades Negras – PCN y el Observatorio de Territorios Étnicos y Campesinos (OTEC) de la Universidad Javeriana de Colombia. Es un mapeo de la presencia territorial de los Pueblos Afrodescendientes en 15 países, el estado de reconocimiento de sus derechos territoriales y la sobreposición con áreas de gran importancia para la regulación y mitigación al cambio climático y sus aportes a la conservación. Los territorios son el espacio para el ejercicio del ser Afrodescendiente. Sin territorios no hay vida ni identidad cultural. Nuestros territorios actualmente son vulnerados, amenazados, sus recursos naturales depredados y las prácticas tradicionales de producción y los conocimientos ancestrales disminuidos. Este atlas intenta dar cuenta de las condiciones en que se encuentran dichos territorios.
Midwives’ Experience, Knowledge, and Perception of Assisting Water Birth in a Hospital Unit - A Qualitative Interview Study
Authors: Wiklund Ingela
Published: October 2024

Background: the opportunity for women to give birth in water vary globally, and in Sweden waterbirth is offered in some of the maternity clinics in the country. An increased demand of water birth from pregnant women have been noticed. Research on waterbirth mainly focuses on women's experiences, but rarely on midwives' knowledge and perception. Aim: the aim of this study was to describe midwives' experience of, and knowledge about waterbirth. With a qualitative method and inductive approach, 16 midwives with varying experience, working in a clinic that provides waterbirths, were interviewed. The interviews were analyzed with content analysis. Results: The difficulty of estimating bleeding in water was perceived as a challenge. Also, the surveillance of the baby when CTG was used was another challenge. The working environment for the midwife working in positions where they had to lean into the pool was also mentioned as a challenge. The state of education and knowledge was varying, but trusting one's skills in assisting a waterbirth was based both in the level of experience as a midwife and in the number and frequency of assisting waterbirths. The clinic's policies and guidelines on waterbirth also played a part in the perceived safety. Conclusion: midwifes experienced of waterbirths was that waterbirth is positive both for the woman and the midwife herself. Knowledge was obtained mainly through practical experience, other midwives, and clear guidelines.
Psicologia e ecologia
Authors: Ponce Guilherme Dutra
Published: October 2024

Este trabalho procura investigar, na escuta analítica, as reverberações de uma postura crítica tanto à percepção dita “natural”, quanto à memória dita “de sujeito”, em especial como propõe Deleuze, em seu estudo de Bergson e Cinema, e Guattari, ao elaborar uma ecologia dos functores ontológicos. O trabalho pretende ativar um modo de inconsciente que se aproxima mais da concepção imanente de Terra-floresta dos Yanomami, especialmente a partir de relatos do xamã Davi Kopenawa; pensando então o inconsciente a partir de seu valor de fertilidade, rumo aos cristais de tempo, ou ritornelos, dos quais o tempo nasce. Tempo heterogêneo, que nos compõe em termos de durações. Pretende-se, por fim, expor e analisar como isso se desenrola na prática clínica.
Microplastics and behavioral changes in fish: an integrative review
Authors: Alves Matheus Bilio , Acioly Thiago Machado da Silva , Oliver Jose Alberto Iannacone , Jawad Laith Abd Jalil , Sousa Alana Lislea de , Santos Diego Amorim dos , Viana Diego Carvalho
Published: October 2024

Plastics are materials that persist for a long time in the environment, and their fragments, called microplastics (MPs), are abundant pollutants in marine environments, potentially affecting fish. The objective of this integrative review is to analyze the existing scientific literature to understand the effects of microplastics on behavioral changes in fish, identify the main behavioral alterations in exposed animals, and evaluate the primary types of plastics and their concentrations. The methodology was based on an extensive search of the scientific literature using the combination of descriptors: "microplastics AND fishes AND behavioral changes," utilizing the databases Science Direct, CAPES Periodicals, and Wiley Online Library. A total of 6.401 articles were found, and after all analyses using inclusion and exclusion criteria, 11 articles were included, fully read, and deeply analyzed. The research highlighted the main types of microplastics, their concentrations, and the observed behavioral impacts on different fish species. The results indicate that microplastics significantly affect fish behavior, causing alterations in swimming, locomotion, growth, development, social and reproductive interactions, and physiological and genetic impacts. It is concluded that microplastics represent a substantial threat to aquatic ecosystems and biodiversity.
Art of earth: the ancient city of Gaochang in China on the silk road
Authors:   School of Design and Art, Jiangxi University of Finance and Economics, Nanchang, China, TANG Yiping
Published: October 2024

This paper examines the geographical position and environmental characteristics of the ancient city of Gaochang in Xinjiang, China, along with its social and historical development. It summarizes the five significant historical periods of Gaochang until its abandonment in the early Ming Dynasty: the barrier of Gaochang, the county town of Gaochang, the national capital of Gaochang, the city of the Western State of the Tang Dynasty, and the Uyghur capital of Gaochang. The study analyses the changes in the city’s shape and layout during each period, systematically discussing aspects such as functional partitioning, wall and gate settings, and other structural features. Finally, it expounds on the building techniques and their value, highlighting that the Gaochang city site is the largest existing site of an ancient Chinese city in the Xinjiang region, covering an area of approximately 2.2 million square meters and possessing significant historical, scientific, and artistic value.
Henosepilachna vigintioctopunctata (Fabricius) (Coleoptera: Coccinellidae), a serious insect pest of Solanum nigrum (A medicinal plant) in Jammu region (J&K)
Authors: Sharma Baldev , Tara J. , Sudan Madhu
Published: October 2024

Henosepilachna vigintioctopunctata Fab. was recorded as a destructive pest of Solanaceous and Cucurbitaceous crops in various parts of District Rajouri of Jammu division of Jammu and Kashmir State. It attacks Solanum nigrum (Solanaceae) which is used both in Ayurvedic and Allopathic medicines. Both adults and larvae cause a typical lace-pattern damage to the leaves of the plant. Its taxonomic status, distribution, descriptive notes. etc. have been described in the present paper.
DERIN ÖĞRENME TABANLI İŞYERI KAMERASI ILE GERÇEK ZAMANLI KIŞISEL KORUYUCU EKIPMAN VE DEPO GÜVENLIĞI TESPITI
Authors: Karakan Abdil , Oğuz Yüksel
Published: October 2024

İş kazalarının büyük bir çoğunluğu basit tedbirlerle önlenebilecek seviyededir. Bunların başında çalışanların kullanması gereken kişisel koruyucu ekipmanları gelmektedir. Yapılan çalışmada bir iş yeri kamerasından alınan görüntüler ile gerçek zamanlı olarak kişisel koruyucu ekipmanlarının tespiti gerçekleştirilmiştir. Bunun için iş yeri kamerasından alınan görüntülerden bir veri seti oluşturulmuştur. Bu veri seti 6125 tane fotoğraftan oluşmaktadır. Ayrıca fotoğraflar üzerinde gri tonlama, eğim eklenmesi, bulanıklaştırma, değişkenlik eklenmesi, gürültü eklenmesi, görüntü parlaklığı değişikliği, renk canlılığı değişikliği, perspektif değişikliği, boyutlandırma ve konum değişikliği eklenmiştir. Bu eklemeler ile kameradan meydana gelebilecek herhangi bir bozulmaya karşı oluşacak hata en aza indirilmiştir. Fotoğraflar üzerinde yapılan değişiklikler ile veri setini oluşturan fotoğraf sayısı 21079’a yükselmiştir. Oluşturulan veri seti YOLOv5 mimarisinde çalıştırılmıştır. Çalışmada kask, ayakkabı, yelek, yolda, yolda değil, yeleksiz, ayakkabısız, apron ve kasksız olmak üzere 9 çeşit kişisel koruyucu ekipmanın tespiti gerçekleştirilmiştir. Çalışma sonucunda ortalama doğruluk 97.3%, mAP 93.8% ve recall 91.7% gerçekleşmiştir.
Simulation & Control of Crude Oil Desalter of Khartoum Refinery
Authors: ALI ARAFA , Ali Mohammed Alhussein Adil , Abdalla Gasmelseed Gurashi
Published: October 2024

A desalting unit of crude oil is required to reduce the salt content in the crude to an acceptable value. Then the control technique is required to change the desalting process properly in order to eliminate the unfavorable effect of the disturbances which is reflected on the amount of salts that existed in the desalted crude. The concentration of calcium salts that exist in the crude oil of Khartoum refinery is about 450 – 600 ppm to be reduced to about 11 ppm, hence different control mechanisms were proposed for controlling the concentration of calcium salts in the desalted crude oil of Khartoum refinery. The flow rate of the decalcium agent (decalcinizer) was used to manipulate the deviation in concentration from the set point, then the mathematical model was determined using Matlab software and the transfer function was estimated using the system identification toolbox. Simulink feature of Matlab was used to draw the control loop and the optimum settings of controller parameters were estimated by tuning the controller under PID-action, P-action, and PI-action, using two different methods, which are PID tunner method and Ziegler-Nichols (Z-N) tuning method. These settings were used for overshoot and peak deviation investigation, then the response curve was drawn for three types of the controller and the proportional integral derivative controller (PID Controller) resulted in highest value of controller gain lowest overshoot and peak deviation, and shortest settling time. Root Locus Niquest and bode criteria were used to investigate the system stability and the last two methods resulted in a stable system. Another mechanism for concentration control using the flow rate of the inlet water as a manipulated variable was proposed, the results were compared with that obtained from the flow rate of decalcinizer, and the decalcinizer flow rate gave better results than the inlet water flow rate.
COMBINED USE OF TEXT COMPONENTS STUDY TECHNOLOGIES IN THE FORMATION OF FOREIGN LANGUAGE COMMUNICATION SKILLS OF A FUTURE PHARMACIST
Authors:   Kemerovo State Medical University, Gukina Ludmila V.
Published: October 2024

The article examines the combined use of study technologies when working with a foreign language text of an annotation for a medicinal product to develop professionally oriented communication skills in students, which is implemented in the academic realities of training a future pharmacist at a medical university, taking into account the requests for the communicative competencies of a specia­list in modern pharmacy practice. The relevance of turning to technologies for studying medical terms in the educational process by decoding the meanings of their components and the meanings embedded in the entire text of the annotation is shown. The material for critical analysis was the corpus of communicative tasks for the texts of annotations to medi­cines. The texts are presented in the textbook, the purpose of which is to remove terminological difficulties from students in the process of forming professio­nally oriented communication at all stages of student lear­ning. Examples of the implementation of educational and research technolo­gies are given. What is novel is the attempt to analyze the academic conditions in which the formation of foreign language communicative competencies of a future pharmacist should be implemented, and to identify current pedagogical and technological strategies that, when used in combination, can compensate for problem areas in teaching a foreign language for special purposes and contribute to the development of communication skills in students, relevant for modern pharmacy activities. The results of the study may be of interest to teachers of medical and pharmaceutical universities who teach students a foreign language of medicine and pharmacy.
THE IMPACT OF FAMILY EDUCATION ON SOCIALIZATION AND THE PROFESSIONAL SUCCESS OF A COLLEGE STUDENT
Authors:   College of Industrial Technologies, Romanenko Tatiana V.
Published: October 2024

This article substantiates the importance of the family as a basic social institution, and notes the special influence of family education on the socialization, social and professional success of young people. At the same time, it is emphasized that an unfavorable family atmosphere, in turn, leads to distortion of basic social attitudes, deformation of the value system and behavioral models, and a traumatic effect on a develo­ping personality. The purpose of the study in the context of this article is to analyze the main indicators of family problems of students of the Smolensk College of Industrial Technologies and assess their degree of influence on the learning and socialization process. It is concluded that such families significantly complicate the process of socialization of the student. The authors propose measures of psychological and peda­gogical support for students to offset the negative impact of a dysfunctional family, and also emphasize the need for constant monitoring of the situation and periodic updating of the system of psychological and pedagogical support.
Diversity analysis of livestock-associated Staphylococcus aureus (LA-SA) nasal strains between animal and humans
Authors: Taha Zanan , Ahmed Meqdad , Jwher Dhyaa , Abdulrahman Rezheen , Rahma Hady
Published: October 2024

Background:
Staphylococcus aureus has emerged as a major public health concern. It is a common pathogen in animal and human medicine.
Aim:
Enterobacterial Repetitive Intergenic Consensus Polymerase Chain Reaction (ERIC-PCR) was used to fingerprint 10 strains of S. aureus obtained from nasal swabs in domesticated animals and humans to ascertain how comparable the different strains' genetic makeup was.
Methods:
These isolates were previously identified using standard molecular and microbiological methods. ERIC primers were amplified for all isolates. The dendrogram was generated using PGMA and the Dice similarity coefficient. The strains were genotyped according to the diversity of sample source (human or animal), and the geographic source.
Results:
Ten S. aureus strains were classified into eight “ERIC” kinds (genotypes) using “ERIC-PCR genotyping”, in which the two most common clones were genotypes 8 and 2, which were represented by one strain from humans, one from cows, and two strains from sheep. Two strains derived from separate geographic areas and from different sample sources (human and cow) were determined to share the same genotype. Another two strains from different geographic areas but from the same sample source (sheep) were categorized under the same genotype. All the remaining strains were classified as a singular genotype.
Conclusion:
This study supports the possible bacterial transmission from animal to human and from animals themselves that usually happens during live animal marketing. Recognizing the interconnected nature of transmission systems and implementing the required approaches to disease prevention and control is essential for mitigating the risks posed by bacterial pathogens.
The effect of aluminum chloride on testicular biometry, hormonal profiles, spermatozoa quality, and spermatogenic cells morphology in mice
Authors: Faizah Zakiyatul , Hendarto Hendy
Published: October 2024

Background:
Infertility is defined as failure to achieve a pregnancy after 12 months or more of regular unprotected sexual intercourse. The prevalence of couples with infertility increased every year. Treatment success for male infertility remains suboptimal despite the advancements of the therapies. Hence, a comprehensive understanding regarding spermatogenesis is needed to improve existing infertility treatments. Animal models are commonly used in studies regarding male infertility. Aluminum chloride (AlCl3) has been established as an infertility-inducing agent.
Aim:
This study investigates the optimal dosage of AlCl3 in infertility mice model.
Method:
Male Balb/c mice, aged 3 months and have proven to be fertile with an average body weight of 26,96, randomly assigned to four groups. The control group received oral gavage with sterile aquadest, while the treatment groups were administrated AlCl3 at doses of 100mg/kgBW, 150mg/kg BW, 200mg/kg BW orally over a 53-day period. Assessment of the sperm motility, concentration, morphology, viability, hormone levels, and testicular histopathology were included in this study.
Results:
Administration of AlCl3 did not significantly affect body weight, testicular weight, and hormone levels. However, semen analysis showed a reduction in seminal parameters among treatment groups, supported by testicular histopathology.
Conclusion:
Utilizing AlCl3 to induce infertility in mice models is not quite effective and displayed variable efficacy across different dosage. Further investigations are needed to elucidate optimal dosage, route of administration, and timing to establish reliable mice infertility models.
COMPETÊNCIAS DO ENFERMEIRO NA PROMOÇÃO DA SAÚDE MENTAL DA PESSOA IDOSA NA ATENÇÃO PRIMÁRIA À SAÚDE
Authors: Silva Jennifer Domiciano Ciriaco da , Carmo Pedro Augusto Paula do
Published: October 2024

Introdução: O envelhecimento pode ser definido como um processo multidimensional que envolve fatores biológicos, psicológicos, sociais e culturais. Nos últimos anos houve um grande crescimento da população idosa no Brasil, esse aumento se deve ao avanço da medicina e a baixa fecundidade, nos mostrando que o envelhecimento populacional é uma consequência do desenvolvimento, relacionando-se diretamente com a qualidade de vida. Objetivo: Compreender quais as competências do enfermeiro na promoção da saúde mental da pessoa idosa no contexto da atenção primária à saúde. Método: Visando alcançar os objetivos propostos, optou-se por um estudo de reflexão teórica com abordagem qualitativa. Resultados: O enfermeiro inseriu-se como o profissional que primariamente acolhe a pessoa idosa na atenção primária a saúde. Nesse contexto o enfermeiro exerce papel de liderança ao organizar e coordenar o cuidado que será dispensado a pessoa idosa no âmbito da atenção primária a saúde.
The implementation of the Trading Business License (SIUP) Permit Service at the Investment Agency, Integrated One-Stop Service Permit Service of Pangkalpinang City
Authors: Nugroho  , Rachman Bustami , Rulinawaty
Published: October 2024

This research investigates the implementation of the Trading Business License (SIUP) licensing service at the Investment Service, One Stop Integrated Licensing Service (PTSP) Pangkalpinang City. The method used in this research is qualitative, which was carried out through observation, interviews and documentation studies, and the Quantitative Method, which was collected through an evaluation survey of the level of satisfaction of entrepreneurs, was carried out through a direct survey of business permit applicants who had used the SIUP licensing service at PTSP Pangkalpinang City. This survey was conducted on 100 entrepreneurs in Pangkalpinang using a questionnaire based on satisfaction indicators, such as ease of licensing process, clarity of information provided, responsiveness of officers, and overall satisfaction with services. The research results show that although there are efforts to implement integrated licensing services, there are still challenges in integrating information systems, the quality of officer services, and the gap between entrepreneurs' expectations and reality. The implications of this research highlight the importance of improving technological infrastructure, training human resources, and improving licensing service policies and procedures to improve service quality and support economic growth in Pangkalpinang City.
Legal Regulation of the Use of Physical Force by Police Officers Under Martial Law
Authors: Anisimov Dmytro
Published: October 2024

The legal regulation of the use of physical force by police officers is a critical issue in the system of public safety, particularly under martial law. In modern times, as countries face growing national security threats, the problem of ensuring that police use force both legally and appropriately becomes increasingly important. Martial law, which involves extraordinary measures by the state to protect its sovereignty and citizens, often grants law enforcement agencies expanded powers. These powers are intended to facilitate a quicker response to threats that may endanger both public order and national security. However, such expanded powers raise legal and ethical concerns regarding the boundaries of acceptable force. In the context of martial law, there is an urgent need to formalize the legal frameworks that govern the use of physical force by police officers. This includes not only national legislation but also international agreements that set standards for law enforcement conduct during crises. The complexity of maintaining public safety during military operations requires specific guidelines to ensure that law enforcement agencies act within the bounds of the law, while still effectively protecting citizens. This article focuses on analyzing how martial law affects the legal regulation of the use of force by police officers, using Ukraine as a case study. It highlights the key legislative challenges that have emerged in Ukraine since the introduction of martial law, such as ambiguities in the scope of police authority and gaps in existing regulations. Additionally, it offers recommendations for addressing these issues, emphasizing the need for clear and precise legal standards that balance public safety and the protection of human rights, even in times of crisis.
THE EFFECT OF SELF-ACUPRESSURE ON REDUCING BLOOD PRESSURE, HEADACHE AND SLEEP QUALITY DISORDERS IN HYPERTENSIVE PATIENTS
Authors: Yuniarsih Sri Mumpuni , Hasanah Nunung , Martani Rahajeng Win , Afifah Umum
Published: October 2024

Hypertension is still a major health problem in Indonesia. Various efforts to overcome the problem of hypertension have been made, both pharmacological and non-pharmacological treatments. A therapy based on the patient's habits or culture will certainly be easier to implement and obey by. Therefore, this study aims to analyze the effect of self-acupressure on blood pressure, headache, and sleep quality of hypertensive patients. The research method used is a quasi-experiment, single-group pre-post-test design. The sample in this study were hypertensive patients who fit the inclusion and exclusion criteria at Wonokerto Health Centre, Pekalongan Regency. The data analysis used was univariate and bivariate analysis. Bivariate analysis used paired group t-test technique. The results showed that there was an effect of self-acupressure in reducing systolic blood pressure (p-value: 0.004), headache pain scale (p-value: 0.001), and decreased sleep quality disorder score (p value: 0.000). Massaging at acupressure points has the effect of improving blood flow, stimulating endorphin hormones and providing a relaxing effect so that it can reduce blood pressure, headache pain scale and sleep quality disturbance scores. Recommendations for future research are to add a control group and/or compare it with other independent complementary therapy techniques.
EXAMINING CLINICAL STUDIES ABOUT CUPPING THERAPY IN TURKEY: A SYSTEMATIC REVIEW AND BIBLIOMETRIC ANALYSIS
Authors: Ucun Yasemin
Published: October 2024

There is insufficient quantitative data available on the characteristics of research conducted on cupping therapy. This insufficiency complicates our ability to achieve a more profound understanding of the subject.  The primary aim of this work was to assess the outcome of clinical studies outputs in cupping therapy and discuss methodological gaps. Six databases PubMed, Cochrane Library, Medline, TUBITAK ULAKBIM DergiPark, Science Direct, and Google Scholar, were systematically searched from their inception to January 2024. Performance analysis was made in the study. Frequency and distributions were analyzed with SPSS 24. The software Wordclouds software was used to generate visualization. Within the scope of the research, 26 studies that met the selection criteria were accessed. It was determined that the majority of the studies (46.16%) were written in 2019-2021. The most used technique was  3 S (73.07%), and the most preferred point was du 14 point. While the top two variables are oxidative stress and heavy metal levels, the co-word analysis of keywords showed that "wet cupping therapy" was the largest single node. The findings from this bibliometric study provide the current status and productivity in clinical research of cupping therapy over the past ten years. It is seen that despite the challenges facing the ﬁeld of cupping research, which include standardization, legal, and reporting quality, there has been an increase in publications to mitigate disease-related symptoms in clinical populations.
PRESERVING NUTMEG : HISTORICAL SIGNIFICANCE, MEDICINAL BENEFITS, AND CLIMATE CHANGE THREATS TO INDONESIAN NUTMEG
Authors: Anripa Nuralfin , Lone Vicka Frantya
Published: October 2024

Over the past thousand years, scholars and practitioners, drawing from diverse fields including culture, philosophy, sociology, and history, have meticulously documented the intricacies of various medicinal substances and their applications. In this continuum of knowledge, nutmeg, a quintessential spice of Indonesian heritage, has held a prominent place.  This study aims to explore the historical significance of nutmeg in Indonesia, its role in medicinal practices, and the threats posed by climate change to nutmeg cultivation. The research seeks to provide valuable insights into the cultural and historical importance of nutmeg in Indonesian society, as well as its medicinal benefits. Additionally, the study aims to analyze the potential impact of climate change on nutmeg production in Indonesia. The study uncovered nutmeg's diverse significance in Indonesia across historical, cultural, medicinal, and economic realms. It emphasized nutmeg's medicinal potential and the climate change challenges to its production. Findings stressed the necessity of robust climate policies and proactive adaptation strategies to ensure nutmeg farming sustainability. In conclusion, this study highlights nutmeg's historical, medicinal, and climate change-related challenges in Indonesia. It stresses the necessity of comprehensive measures to address climate change impacts and integrate resilience strategies into nutmeg farming practices and policymaking. These findings offer valuable guidance for policymakers and stakeholders to ensure the sustainable growth of Indonesian nutmeg exports amidst environmental changes.
Farmacocinética de antibióticos en pacientes obesos
Authors: Barrantes Araya Daniela , Mesén Jiménez Daniela , Villalobos Madriz Jorge Arturo , Díaz Madriz José Pablo
Published: October 2024

Resumen La obesidad se define como un exceso en la cantidad de grasa corporal, la cual va acorde con el sexo, la edad y la altura de la persona. Es un padecimiento cada vez más frecuente tanto en países de primer mundo como en países en desarrollo; a pesar del aumento de la obesidad, en las últimas décadas las evaluaciones farmacocinéticas aún no toman en consideración la obesidad como una variable por medir en sus estudios. Se conoce que la obesidad mórbida puede llegar a producir cambios fisiopatológicos que pueden afectar la farmacocinética de un fármaco, pero en la actualidad no existe dosificación específica para los antibióticos en pacientes obesos. En la actualidad, la dosificación se basa en las características farmacocinéticas de los medicamentos y el criterio del profesional en salud. Es fundamental comprender la farmacodinamia de los antibióticos y las dosis correctas para el tratamiento adecuado y seguro de la población obesa.
Impacto del peso e índice de masa corporal en la anticoncepción de emergencia con Levonorgestrel
Authors: Blanco Naranjo Erick , Garita Fallas Yorlin , Chavarría Campos Gary
Published: October 2024

Resumen La anticoncepción de emergencia es una de las alternativas para evitar embarazos no deseados en mujeres que han tenido relaciones sexuales hasta 120 horas después del coito sin protección o cuando el método utilizado falló. El levonorgestrel es el anticonceptivo oral de emergencia más utilizado debido a su eficacia y perfil de seguridad. Este medicamento es empleado, principalmente, por mujeres jóvenes, estudiantes, con una vida sexual activa. Su efectividad y parámetros farmacocinéticos (tiempo de concentración máxima, concentración máxima y área bajo la curva) se ven alterados en pacientes con un peso >75 kg o con un índice de masa corporal >30 kg/m2.
Anemia en el perioperatorio
Authors: Ruiz Loría Viviana , Elizondo Vincenzi Giuliana , Echeverría Miranda Marisabel , Echevería Flores Ana Sofía
Published: October 2024

Resumen La anemia, definida como un descenso en la hemoglobina, en el perioperatorio está relacionada con el aumento del uso y requerimiento de transfusiones sanguíneas. Esta, además, constituye un mayor riesgo de resultados negativos en el postoperatorio (como mayor estancia intrahospitalaria y costos de esta). El manejo con transfusión conlleva a varios efectos adversos y a un aumento de mortalidad y morbilidad, por lo cual es necesario optimizar e individualizar cada caso en específico con un manejo multidisciplinario entre médicos tratantes y anestesiólogos para crear un aspecto restrictivo sobre cuándo conviene realmente transfundir o no. Dentro de los parámetros a tomar en cuenta en el perioperatorio están las condiciones y clínica del paciente, la enfermedad específica a tratar, la edad, si tiene alguna enfermedad crítica o cardíaca de fondo y un examen que demuestre la hemoglobina al menos 2 semanas previas a la cirugía para detectar la anemia a tiempo. Para esto, se ha desarrollado un esquema que consta de tres pilares los cuales son los siguientes: detección y tratamiento de anemia preoperatoria, reducción de la pérdida sanguínea perioperatoria en cuanto a prevención de coagulopatías y la optimización de la tolerancia de la anemia. El objetivo de este artículo es definir la anemia como tal, evaluar las causas más frecuentes en el perioperatorio, definir un manejo apropiado para la misma y concluir en aspectos importantes a tomar en cuenta para optimizar tanto el resultado positivo del paciente como la utilización de recursos.
Experiencia en terapia con plasma en pacientes con COVID-19
Authors: Ortiz Leitón Fabián , Castillo Peña Karol Dayanna
Published: October 2024

Resumen La enfermedad del coronavirus (COVID-19) representa una de las mayores epidemias que enfrenta el mundo y está desencadenando una crisis de salud global que inició a principios del año 2020. Hasta la fecha, no existe una terapia dirigida para esta enfermedad. El plasma convaleciente es una opción de tratamiento interesante contra el COVID-19 porque se ha utilizado con éxito en otros brotes virales en el pasado en distintas partes del mundo. Esta terapia consiste en recolectar plasma con anticuerpos de individuos que se han recuperado de la enfermedad viral. Se considera que es la única estrategia a corto plazo para dar inmunidad inmediata a los individuos susceptibles. Esta revisión aborda el posible mecanismo de acción del plasma restaurador, se dan recomendaciones de quienes pueden ser donadores y se describe las características de seguridad y administración del plasma. Además, se brinda una descripción general sobre el COVID-19 y los procedimientos necesarios para implementar la terapia.
Hígado graso agudo en el embarazo
Authors: Gómez Hernández Cinthya , Riogionni Benavides Valeria , Coto Chaves Catalina
Published: October 2024

Resumen El hígado graso agudo es una enfermedad exclusiva del embarazo que se caracteriza por infiltración grasa microvesicular de los hepatocitos, lo cual puede llevar a falla hepática fulminante si no se realiza un diagnóstico y manejo temprano de la enfermedad. Se presenta generalmente en el tercer trimestre del embarazo. Su causa es desconocida, pero se ha encontrado una asociación importante con algunas deficiencias enzimáticas, principalmente de 3-hidroxiacil- CoA deshidrogenasa de cadena larga (LCHAD, por sus siglas en inglés). Se han demostrado algunos factores de riesgo para desarrollar esta condición, algunos de ellos son los siguientes: mujer nulípara, bajo índice de masa corporal, antecedente de hígado graso agudo en el embarazo (HGAE), gestación múltiple y feto de sexo masculino. Su diagnóstico definitivo es histológico, pero por las condiciones maternas se utilizan características clínicas y datos de laboratorio como guía hacia una sospecha diagnóstica. Una vez que se haya establecido un diagnóstico certero, se debe terminar con el embarazo para una subsecuente resolución del cuadro. Dicha patología es una forma reversible de falla hepática que, por lo general, no requiere trasplante hepático. El HGAE tiene cifras elevadas de mortalidad tanto para la madre como para el feto, pero por fortuna su incidencia es rara.
Piedra blanca: a propósito de un caso en Pérez Zeledón
Authors: Jiménez Badilla Iveth , Gómez Sáenz Alexander
Published: October 2024

Resumen La piedra blanca es una micosis causada por el género Trichosporon spp, que genera nódulos blandos y blanquecinos principalmente en pelo del cuero cabelludo. Se asocia a regiones calientes y tropicales del mundo, aunque se dice que es cosmopolita. Se presenta el caso de una niña de 5 años de edad que consulta en el pueblo de Pérez Zeledón, Costa Rica, por la presencia asintomática de numerosos nódulos blanquecinos de 1 mm de diámetro en el cabello de la cabeza, que se confirman como piedra blanca y se identifica a la especie Trichosporon asahii como el agente causal por el sistema VITEK® 2. Se indica como recomendaciones de tratamiento el corte del cabello y el uso de champú con ketoconazol al 2%, así como la suspensión de actividades de riesgo como el lavado frecuente del cabello, pobre secado y trenzado o recogida del mismo cuando aún está húmedo. El caso se resuelve a los dos meses de seguir las recomendaciones brindadas. Se resalta la coincidencia con reportes previos de series de casos en otros países latinoamericanos, que señalan a las niñas como a la población más afectada. Además, se pretende concientizar sobre dicha micosis; sus características, diagnóstico y tratamientos alternos al corte radical del cabello.
El divertículo de Meckel en el paciente pediátrico
Authors: Polanco Daniela , Ramírez Joshua , Caro Pizarro Valeria , Arroyo Quirós Alejandra
Published: October 2024

Resumen En este artículo se presenta una breve revisión bibliográfica acerca de la clínica, el diagnóstico y el manejo del divertículo de Meckel, una de las malformaciones congénitas más comunes. Este comprende un vestigio embrionario del conducto onfalomesentérico, lleva el nombre de divertículo verdadero al estar compuesto por todas las capas de la pared intestinal; no obstante, en ocasiones, se encuentra acompañado de tejido ectópico. Este mismo se presenta con una incidencia de un 2 % en la población general, además de ser una de las anormalidades del tracto gastrointestinal más prevalentes en la población pediátrica. Generalmente, no presenta síntomas por sí solo, su clínica se relaciona, principalmente, con sus complicaciones, tales como el sangrado digestivo y la obstrucción o perforación intestinal. El Scan de Meckel es una de las herramientas más importantes al momento del diagnóstico. El abordaje de elección es quirúrgico en los pacientes en edad pediátrica.
A Study on Using Machine Learning to Predict Winner in Multiplayer Online Battle Arena (MOBA) Game
Authors: Tangniyom Nattapat , Boonma Pruet
Published: October 2024

Realm of Valor (RoV) is a famous multiplayer online battle arena (MOBA) game. An average of 25 million games are played daily in Thailand alone. The game also competes in international events, with millions of U.S. dollars in the prize pool. However, the game is very complex and requires a player to have high experience to win. In particular, the hero selection process that each user has to perform at the beginning of each game because the set of selected heroes can affect the game outcome, but there are many heroes to be selected. This paper compares machine learning techniques to predict the winner's side based on the player's and opponent's selection of heroes and the relationship among the selected heroes. Three traditional machine learning techniques, namely, k-Nearest Neighbor, Logistic Regression, and Decision Tree, are compared against ensemble learning with their optimized parameters. The algorithms are evaluated using k-fold cross-validation, and the accuracy of each algorithm is measured. The results show that winning predictions can be improved by considering the relationship among selected heroes. Also, ensemble learning can compete with traditional learning.
Comparative Analysis of DNN, GBT, and KNN Models for Network Intrusion Detection
Authors: Vatcharaphrueksadee Amornvit , Viboonpanich Rattikan , Charoenmairungrueang Wilairat
Published: October 2024

Network intrusion detection is critical to cybersecurity, aiming to identify and mitigate unauthorized access and attacks on computer systems and networks. This study evaluates the effectiveness of three machine learning techniques—deep neural networks (DNN), gradient boost trees (GBT), and k-nearest neighbors (KNN)—in detecting network intrusions. The performance of these models was assessed using a comprehensive dataset of 2,540,047 records encompassing 49 features across nine attack categories. The results indicate that GBT outperforms DNN and KNN in accuracy and robustness. These findings highlight the potential of GBT for enhancing intrusion detection systems and contribute valuable insights into the comparative performance of different machine learning algorithms in cybersecurity applications.
Isolation of Fiber-Cellulose and Characterization from Oil Palm Frond for 3D and 4D Printing Materials Application
Authors: Manosong Warunee , Nuanla-ong Methawee , Udomvech Anurak
Published: October 2024

The oil palm frond (OPF), a primary biomass derived from agricultural waste in oil palm production, holds significant potential for evolving into cellulose fiber. Leveraging natural materials for cellulose extraction aligns with environmental sustainability. In this study, we focus on separating cellulose fibers from OPF biomass. The OPF is divided into its leaflet and frond-axial parts, undergoing a sequence of steps: dewaxing, alkaline treatment, delignification, hydrogen peroxide treatment, and final filtration. These steps assess both efficacy and cellulose fiber outputs. Notably, the axial and leaflet portions yield cellulose fibers, effective as an initial extraction step before progressing to nanoscale slicing. Quantitatively, extraction yields indicate that 14.13% and 19.52% of the 100 g leaflet and frond-axial portions can be harvested. SEM images confirm well-dispersed individual fibers. Additionally, GCMS results reveal slightly higher carbon dioxide gas in the palm leaflet sample than in the palm frond-axial sample after five days of water soaking. This procedure efficiently initializes OPF for cellulose extraction, positioning it as an initial ingredient for subsequent 3D/4D printing material production.
Phytochemical Analysis and Biological Activities of Propolis from Geniotrigona thoracica: Evaluating its Therapeutic Applications
Authors: Bunkaew Kannika , Ponpichai Petcharat , Lertworapreecha Monthon , Maitip Jakkrawut , Chanasit Wankuson
Published: October 2024

Propolis is a substance that safeguards the bee hive against physical and microbiological threats. This research assessed the phytochemical properties and biological effects of propolis produced by stingless bees Geniotrigona thoracica collected from Phatthalung, Southern Thailand. The findings revealed that the ethanolic extract propolis (EEP) from G. thoracica exhibited antibacterial properties against certain foodborne pathogens (Bacillus cereus, Staphylococcus aureus, Escherichia coli, and Salmonella Typhimurium) with moderate to strong zone of inhibition (ZOI) in the range of 10 mm ≤ ZOI ≤ 15 mm. Additionally, the extract propolis demonstrated antioxidant activity, achieving up to 80% DPPH radical scavenging when 50 mg/mL EEP was tested. Furthermore, the crude propolis extract showed anti-inflammatory effects on macrophage cells, resulting in a 72.9% reduction in nitric oxide (NO) levels in LPS-activated RAW 264.7 cells exposed to 100 mg/mL of EEP. The GC-MS chromatogram identified the phytochemical compositions of the EEP, with Lup-20(29)-en-3-ol or lupeol (25.42%) and β-amyrone (22.66%) as the major compounds, both triterpenoid derivatives. Other notable constituents included alkane hydrocarbon pentacosane (6.63%), fatty alcohol cis-9-eicosenol (4.23%), and phenolic compound 3-pentadecylphenol (3.86%). Therefore, the EEP derived from G. thoracica, possessing such diverse biological activities, holds promise for medicinal and functional food applications.
ประสิทธิผลการจัดการทางกายภาพบำบัดต่อความสามารถในการทรงตัวของผู้ป่วย ข้อเข่าเสื่อมเชื่อมโยงจากชุมชนสู่โรงพยาบาล
Authors: แปลนดี ปิยวรรณ
Published: October 2024

โรคข้อเข่าเสื่อมเป็นปัญหาสาธารณสุขสำคัญของประเทศไทย อาการของโรคส่งผลให้เกิดความทุกข์ทรมานและทำให้สมรรถภาพทางกายลดลง โดยเฉพาะความสามารถในการทรงตัว การศึกษาแบบกลุ่มเดียววัดซ้ำแบบอนุกรมเวลานี้มีวัตถุประสงค์การวิจัยเพื่อศึกษาประสิทธิผลการจัดการทางกายภาพบำบัดต่อความสามารถในการทรงตัวของผู้ป่วยข้อเข่าเสื่อมเชื่อมโยงจากชุมชนสู่โรงพยาบาล โดยใช้หลักการ 4 หมอ กลุ่มตัวอย่างเป็นผู้ป่วยข้อเข่าเสื่อมระดับปานกลางถึงรุนแรง จากการประเมิน Oxford Knee Score จำนวน 24 ราย ก่อนเข้าสู่กระบวนการวิจัยกลุ่มตัวอย่างจะได้รับการอบรมและฝึกปฏิบัติตามโปรแกรมการจัดการทางกายภาพบำบัดเพื่อสร้างความเข้าใจและเสริมทักษะการเข้าร่วมวิจัย แล้วทำการตรวจประเมินความสามารถในการทรงตัวก่อนการวิจัยสัปดาห์ที่ 0 ระหว่างการวิจัยสัปดาห์ที่ 4 และหลังการวิจัยสัปดาห์ที่ 8 ตามลำดับ วิเคราะห์เปรียบเทียบความแตกต่างของข้อมูลก่อนและหลังการวิจัย โดยใช้สถิติ Repeated measurement one-way ANOVA ผลการวิจัยพบว่าผู้ป่วยข้อเข่าเสื่อมที่ได้รับโปรแกรมการจัดการทางกายภาพบำบัด ต่อเนื่องเป็นระยะเวลา 4 และ 8 สัปดาห์ มีผลช่วยให้ความสามารถในการทรงตัวดีขึ้น อย่างมีนัยสำคัญทางสถิติ (p-value <0.001) สรุปผล การจัดการทางกายภาพบำบัดช่วยฟื้นฟูสมรรถภาพการทรงตัวของผู้ป่วยข้อเข่าเสื่อมได้
ผลทันทีของการติดเทปพยุงกล้ามเนื้อและการออกกำลังกายเพื่อควบคุมการทำงานของกล้ามเนื้อสะบักต่อความแข็งแรงของกล้ามเนื้อรอบสะบัก ความยาวของกล้ามเนื้ออกในนักกีฬาที่ใช้แขนเหนือศีรษะที่มีภาวะของการเคลื่อนไหวของสะบักที่ผิดปกติ
Authors: เพ็ชรวิเศษ หฤทัย , เฮงตระกูล พชร , มะลิวงษ์ อนุวัช , นำชัย ญาณวัฒน์ , พกุลานนท์ ศศิมา
Published: October 2024

การศึกษานี้เป็นการศึกษาเชิงทดลองที่มีวัตถุประสงค์เพื่อศึกษาผลทันทีของการติดเทปพยุงกล้ามเนื้อ และการออกกำลังกายแบบควบคุมการทำงานของกล้ามเนื้อรอบสะบัก ต่อความแข็งแรงของกล้ามเนื้ออัปเปอร์ทราปีเซียส (UT) กล้ามเนื้อมิดเดิลทราปีเซียส (MT) กล้ามเนื้อโลเวอร์ทราปีเซียส (LT) กล้ามเนื้อกล้ามเนื้อเซอร์ราตัสแอนทีเรีย (SA) กล้ามเนื้อหมุนไหล่เข้าและออก (MR, LR) และความยาวของกล้ามเนื้อเพคโทราริสไมเนอร์ (PM) ของนักกีฬาที่ใช้แขนเหนือศีรษะที่มีการเคลื่อนไหวของสะบักที่ผิดปกติ นักกีฬาชายที่ใช้แขนเหนือศีรษะและมีการเคลื่อนไหวของสะบักที่ผิดปกติจำนวน 44 คน แบ่งโดยการสุ่มเป็น 2 กลุ่ม กลุ่มละ 22 คน ได้แก่กลุ่ม ก (A) ได้รับการติดเทปพยุงกล้ามเนื้อบริเวณสะบัก และกลุ่ม ข (B) ออกกำลังกายเพื่อควบคุมกล้ามเนื้อโดยทำการประเมินตัวแปรก่อนและหลังการทดลอง ผลทันทีของการออกกำลังกายเพื่อควบคุมกล้ามเนื้อทำให้กำลังกล้ามเนื้อ UT, MT, LT, SA และ LR เพิ่มมากขึ้นภายหลังการทดลอง (p-value ≤0.05) อย่างก็ตามไม่มีการเพิ่มกำลังกล้ามเนื้ออย่างมีนัยสำคัญทางสถิติในกลุ่มที่ติดเทปพยุงกล้ามเนื้อ หลังการทดลองความยาวของกล้ามเนื้อ PM ไม่มีการเปลี่ยนแปลงในทั้งสองกลุ่ม การออกกำลังกายเพื่อควบคุมกำลังกล้ามเนื้อรอบสะบักมีผลทันทีในการเพิ่มกำลังกล้ามเนื้อรอบสะบัก และกล้ามเนื้อหมุนแขนออก
Respiratory Effects and Pulmonary Functions Related to Wood Dust Exposure among Workers in a Rubber Wood Factory
Authors: Supapvanich Chompunuch , Yeekew Thanawat , Pechayco Ganfre
Published: October 2024

This study aimed to determine the effects of wood dust exposure on respiratory symptoms and pulmonary functions in wood dust factory workers and the association between wood dust exposure and pulmonary functions. This cross-sectional study comprised of one hundred workers who answered a self-reported questionnaire. Two factory areas, the production department and the back office, were explored using stationary air sampling. The wood dust concentration was collected using NIOSH Method 0600. Pulmonary function parameters were evaluated through spirometry. A descriptive statistics analysis was done for personal information. Binary logistic regression determined the association between wood dust exposure and respiratory symptoms. The prevalence of respiratory symptoms related to wood dust exposure at work was 49.00 percent. Three major symptoms in the exposed group includes chest pain, shortness of breath, and asthma. The average amount of PM10 in the saw mill area was significantly higher than in the back office (7.23 vs. 1.60 mg/m3). There was a significant difference in forced expiratory capacity between the reference and exposure groups (mean difference = -4.03, p-value = 0.011). The adjusted odd ratio showed that the high wood dust-exposed group had a lower runny nose and dry cough than the reference group. All workers need to consider using personal protective equipment with appropriate specifications in the sawmill area and also the other areas where wood dust levels are high. To control the concentration of respirable particles, resource and pathway control must be applied to reduce the concentration of respirable particles in the workplace.