bluuebunny/crossref_metadata_2025 huggingface dataset:
Papillary renal cell carcinoma embedded in an oncocytoma: Case report of a rare combined tumour of the kidney
Authors: Sejben István , Szabó Zoltán , Loránd Márta , Sükösd Farkas , Cserni Gábor
Published: September 2013

An asymptomatic 1-cm large papillary renal cell carcinoma (RCC) embedded in a 3.5-cm large oncocytoma was diagnosed and removed by right nephrectomy in a 68-year-old male investigated for the abdominal symptoms associated with cholelithiasis. The papillary RCC displayed positive immunohistochemical stainings with cytokeratin 7, alpha-methylacyl-CoA racemase and vimentin and was negative for the E-cadherin and CD117 immunostains, whereas the oncocytoma part showed opposite staining patterns. No gains of chromosomes 7 and 17 or loss of chromosome Y was detected in the papillary carcinoma by fluorescent in situ hybridization with centromeric enumeration probes. This finding is in keeping with the morphologic diagnosis of type 2 papillary RCC reported to have lower rates of these characteristic chromosomal changes. The combination of papillary RCC and oncocytoma, two tumours of different postulated origin, is extremely rare. It may represent a simple coincidence, but 2 previous cases and our current one share a few features, including the intimate embedment of the papillary RCC in the oncocytoma, the small size of the RCC and the old age of the patients. This case raises the point that renal oncocytomas can contain a hidden malignant tumour.
Le syndrome du canal d’Alcock ou névralgies pudendales : un diagnostic à ne pas méconnaitre
Authors: Ziouziou Imad , Bennani Hassan , Zizi Mohamed , Karmouni Tarik , El Khader Khalid , Koutani Abdellatif , Andaloussi Ahmed Iben Attya
Published: September 2013

Le syndrome du canal d’Alcock – ou névralgie pudendale – est lié à la compression chronique du nerf pudendal dans la fossette ischio rectale ou au niveau du ligament sacroépineux. Le diagnostic du syndrome d’Alcock est surtout clinique. Les examens complémentaires sont dominés par les explorations électrophysiologiques et le test de bloc anesthésique. Le diagnostic repose sur des critères bien précis, soit les critères de Nantes. La prise en charge doit être globale, comprenant un traitement médicamenteux, des infiltrations, des techniques de neuromodulation, et dans les cas graves ou résistants, un traitement chirurgical qui consiste à libérer le nerf pudendal. Les névralgies pudendales peuvent être rencontrées après traitement d’une incontinence urinaire d’effort par bandelettes sous-urétrales (TVT). Ce syndrome motive des consultations en urologie, car la douleur intéresse le territoire du périnée et des organes génitaux. Des signes urinaires peuvent aussi accompagner cette douleur. Il est donc judicieux de connaître cette pathologie.
Validation of the da Vinci Surgical Skill Simulator across three surgical disciplines
Authors: Alzahrani Tarek , Haddad Richard , Alkhayal Abdullah , Delisle Josee , Drudi Laura , Gotlieb Walter , Fraser Shannon , Bergman Simon , Bladou Frank , Andonian Sero , Anidjar Maurice
Published: September 2013

Objective: In this paper, we evaluate face, content and construct validity of the da Vinci Surgical Skills Simulator (dVSSS) across 3 surgical disciplines.Methods: In total, 48 participants from urology, gynecology and general surgery participated in the study as novices (0 robotic cases performed), intermediates (1-74) or experts (≥75). Each participant completed 9 tasks (Peg board level 2, match board level 2, needle targeting, ring and rail level 2, dots and needles level 1, suture sponge level 2, energy dissection level 1, ring walk level 3 and tubes). The Mimic Technologies software scored each task from 0 (worst) to 100 (best) using several predetermined metrics. Face and content validity were evaluated by a questionnaire administered after task completion. Wilcoxon test was used to perform pairwise comparisons.Results: The expert group comprised of 6 attending surgeons. The intermediate group included 4 attending surgeons, 3 fellows and 5 residents. The novices included 1 attending surgeon, 1 fellow, 13 residents, 13 medical students and 2 research assistants. The median number of robotic cases performed by experts and intermediates were 250 and 9, respectively. The median overall realistic score (face validity) was 8/10. Experts rated the usefulness of the simulator as a training tool for residents (content validity) as 8.5/10. For construct validity, experts outperformed novices in all 9 tasks (p < 0.05). Intermediates outperformed novices in 7 of 9 tasks (p < 0.05); there were no significant differences in the energy dissection and ring walk tasks. Finally, experts scored significantly better than intermediates in only 3 of 9 tasks (matchboard, dots and needles and energy dissection) (p < 0.05).Conclusions: This study confirms the face, content and construct validities of the dVSSS across urology, gynecology and general surgery. Larger sample size and more complex tasks are needed to further differentiate intermediates from experts.
L’évaluation des services sociaux et de santé offerts aux minorités sexuelles par le CSSS Jeanne-Mance
Authors: Dumas Jean
Published: September 2013

Au Québec, l’adaptation des services sociaux et de santé aux besoins en matière de santé des minorités sexuelles demeure peu documentée. Une recherche-action participative, menée au Centre de santé et de services sociaux (CSSS) Jeanne-Mance, à Montréal, s’est donnée comme objectif de mesurer l’adéquation des services de ce CSSS avec les besoins des personnes lesbiennes, gaies, bisexuelles, transgenres et transsexuelles (LGBT). La première phase de la recherche visait à documenter, à l’aide d’entretiens avec des informateurs clés, les enjeux liés à l’adaptation des services. Mis à part l’examen des pratiques déjà développées au CSSS pour répondre à leurs besoins, on retrouve parmi les éléments à considérer la question de l’accueil, le processus d’identification des besoins, les techniques de communication pour développer le lien de confiance de même que les besoins spécifiques à chacun des sous-groupes parmi les minorités sexuelles. L’article soulève également la nécessité de considérer l’amélioration de la formation du personnel et les risques et bénéfices de services spécifiques destinés à ces populations.
Population dynamics of walruses in Greenland
Authors: Witting Lars , Born Erik
Published: September 2013

The historical and current dynamics of the three Atlantic walrus (Odobenus rosmarus rosmarus) populations that occur in Greenland are estimated using age- and sex-structured population models with exponential growth, density-regulated growth and selection-delayed dynamics. These models are integrated with data in a Bayesian framework, where the likelihood of the simulated population trajectories are evaluated from recent abundance estimates and age-structure information from a selective hunt. The overall decline in the Baffin Bay population caused by historical catches is unclear due to incomplete catch reporting prior to 1950s. However, it is estimated that the population declined by 40% from the 1960s to 2005; decreased catches (≈ 140 to ≈ 70) have subsequently allowed this population to increase. The 2012 abundance estimate is 1,400 (95% CI: 1,000-2,000) individuals, and the annual natural growth rate in this population is now 7.7% (95% CI: 6.7-8.9%). Averaging across models, it is estimated that West Greenland/Baffin Island walruses declined by 80% from 7,000 (95% CI: 5,400-10,000) in 1900 to 1,350 (CI: 950-1,950) in 1960. Hereafter they increased to 3,100 (95% CI: 2,500-4,400) in 1993, and owing to increased catches they have experienced a minor decline between 1994 and the early 2000s. Annual catches where then cut from 190 to the current quota of 61, and the population is again increasing with a 2012 estimate of 3,900 (95% CI: 2,500-5,300) individuals. A 2012 estimate of 1,400 (95% CI: 700-3,100) walruses in East Greenland is recovered relative to 1888; the year prior to our first historical catches by European sealers. The historical trajectory, however, is uncertain: Density regulation estimates a relatively flat trajectory, with a maximal depletion in 1890 to 80% of the initial abundance, and a slow continuous increase to almost no current growth. A recovered population is also estimated by selection-delayed dynamics. However, this model estimates a continued increase, and a historical depletion to 2% in 1957. These results are only partially comparable with an earlier assessment for East Greenland. Updated abundance estimates for West Greenland, and modelling with age-structured data from Baffin Bay, have greatly improved our status estimates for Baffin Bay and West Greenland/Baffin Island.
Walrus Odobenus rosmarus research in Svalbard, Norway, 2000-2010
Authors: Lydersen Christian , Kovacs Kit M
Published: September 2013

Herein we report results from studies on walruses in Svalbard conducted in 2000-2010. Data from newly developed satellite relay data loggers (SRDLs) revealed seasonal differences in habitat use of adult male walruses. During winter, they moved into areas of >90% ice concentration, traveling as far as 600 km from ice-free water. Breeding areas deep into the pack ice were identified based on timing of the occupancy and diving behaviour. When the breeding season was over, walruses with SRDLs that were still transmitting locations returned to the coast, showing high site fidelity to the previous year’s summering area. Haul-out data from the SRDLs provided correction factors for an aerial survey of walruses that covered all known haul-out sites within the Svalbard Archipelago. This survey estimated 2,629 (95 % CI; 2,318 – 2,998) walruses to be in Svalbard during August 2006. Blubber biopsies from adult male walruses analyzed for fatty acids (FAs) showed vertical stratification similar to that observed in many other marine mammals. However, differences between layers were less pronounced, possibly because the thick dermis of walruses provides an insulating shield, affecting the FA composition of the outer blubber. The FA composition of the inner blubber most closely resembled the lipids in Mya truncata and Buccinum spp., which are considered the most important walrus prey in Svalbard. A study investigating the use of skin biopsies for assessing levels of organochlorines (OCs) in walruses found a significant relationship between OC levels in skin and blubber. Another contaminant study found a significant decrease in levels of PCBs and DDE in walruses in Svalbard from 1993 to 2002-04. Large inter-individual variation in OC levels was found, although all of the study animals were adult males from roughly the same location. In FA analyses of the inner blubber this variation appeared to be diet-related, with high OC levels having FA compositions in the inner blubber that closely matched seal tissues, while those with low levels matched typical invertebrate prey. Various enzymes, proteins, metabolites, minerals, and hormones were measured in blood samples to serve as baseline data for future health-related studies of both wild and captive walruses. Historical sex-distribution of walruses in southern Svalbard was investigated based on mandible measurements of individuals hunted during the 19th century.The analyses showed that female walruses were once more common in south-eastern Svalbard than they are today.
Preparation of 1,4,5‐Trisubstituted 5‐Acyl‐1,2,3‐triazoles by Selective Acylation between Copper(I)‐Carbon(sp) and Copper(I)‐Carbon(sp2) Bonds with Acyl Chlorides
Authors: Wang Bo , Liu Nan , Shao Changwei , Zhang Qun , Wang Xinyan , Hu Yuefei
Published: September 2013

A one‐pot, three‐component method for preparation of 1,4,5‐trisubstituted 5‐acyl‐1,2,3‐triazoles has been developed based on a highly selective acylation of the copper(I)‐carbon(sp2) bond with acyl chlorides in the presence of the copper(I)‐carbon(sp) bond. The procedure is characterized by high efficiency and simple conditions.

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Palladium‐Catalyzed Intramolecular ipso‐Friedel–Crafts Allylic Alkylation of Phenols via Arylative Activation of Allenes
Authors: Nemoto Tetsuhiro , Nozaki Tomoyuki , Yoshida Mariko , Hamada Yasumasa
Published: September 2013

A novel and efficient synthetic method for functionalized spiro[4.5]cyclohexadienones was developed based on the palladium‐catalyzed sequential process: Heck insertion to an allene–intramolecular ipso‐Friedel–Crafts allylic alkylation cascade. Using 5 mol% of palladium catalyst, a wide variety of spirocycles was obtained in good to excellent yields. The developed cascade process was also applicable to the synthesis of tetrahydronaphthalene derivatives.

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Copper(I) Iodide/Boron Trifluoride Etherate‐Cocatalyzed Aerobic Dehydrogenative Reactions Applied in the Synthesis of Substituted Heteroaromatic Imidazo[1,2‐a]pyridines
Authors: Cai Zhong‐Jian , Wang Shun‐Yi , Ji Shun‐Jun
Published: September 2013

Compared with the well‐known palladium‐catalyzed oxidative dehydrogenation coupling reactions, similar transforms initiated by copper/oxygen have attracted more and more attention. We have investigated a novel construction of heteroaromatic imidazo[1,2‐a]pyridines through copper(I) iodide/boron trifluoride etherate/oxygen‐mediated dehydrogenative reactions of aryl alkyl or alkyl alkyl ketones with 2‐aminopyridines. Four hydrogen atoms are removed and two new CN bonds are formed in one step via the imine formation and oxidative C(sp3)H functionalization.

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Formation of Tertiary Amides and Dihydrogen by Dehydrogenative Coupling of Primary Alcohols with Secondary Amines Catalyzed by Ruthenium Bipyridine‐Based Pincer Complexes
Authors: Srimani Dipankar , Balaraman Ekambaram , Hu Peng , Ben‐David Yehoshoa , Milstein David
Published: September 2013

Dehydrogenative coupling of primary alcohols with secondary amines to form tertiary amides and dihydrogen (H2) is efficiently catalyzed by bipyridyl‐based ruthenium pincer complexes (0.2–1 mol%) under neutral conditions (in case of the dearomatized complexes), or with added catalytic amount of base. The reaction is sensitive to steric hindrance; in the case of amidation of bulky secondary amines a less sterically hindered complex is more efficient. Selective acylation of primary amines in the presence of secondary amines was also demonstrated.

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Phospholipid‐dependent procoagulant activity is highly expressed by circulating microparticles in patients with essential thrombocythemia
Authors: Marchetti Marina , Tartari Carmen J. , Russo Laura , Panova‐Noeva Marina , Leuzzi Annamaria , Rambaldi Alessandro , Finazzi Guido , Woodhams Barry , Falanga Anna
Published: September 2013

This study evaluates the functional procoagulant features of plasma microparticle (MP) to explore the MP contribution to the hypercoagulable state of patients with essential thrombocythemia (ET). Platelet‐free plasma samples were obtained from 73 ET patients (37 positive for the JAK2V617F mutation) and 72 control subjects. The calibrated automated thrombogram (CAT) was performed in plasma samples to determine thrombin generation of MP‐associated tissue factor (TF) and procoagulant phospholipid (PPL) activity, and the STA Procoag PPL assay to measure MP‐PPL activity only. Both thrombin generation and PPL procoagulant activities were found significantly elevated in ET patients compared to controls, and were associated to significantly higher levels of TF antigen and FVIIa/AT complex. Thrombin generation was significantly greater in JAK2‐V617F positive compared to JAK2‐V617F negative patients and normal subjects. Significant correlations were found between the PPL‐assay and the different parameters of the CAT assay. No difference was seen between the thrombosis and no thrombosis group. Prospective studies are needed to test whether MP‐associated thrombin generation and procoagulant activity may predict for thrombosis in these patients. Am. J. Hematol. 89:68–73, 2014. © 2013 Wiley Periodicals, Inc.
Gold‐Catalyzed Tandem Cyclization/Cycloaddition Reaction of Enynones: Highly Regioselective Synthesis of Oxabicyclic Compounds and Naphthyl Ketones
Authors: Song Xian‐Rong , Xia Xiao‐Feng , Song Bo , Tian Xiang , Zhu Hai‐Tiao , Zhou An‐Xi , Liu Xue‐Yuan , Liang Yong‐Min
Published: September 2013

A gold‐catalyzed benzannulation of enynones for synthesizing oxabicyclic compounds and naphthyl ketones with high regioselectivity has been developed. Divergent products can be obtained from the same substrates through different types of cycloaddition. In this reaction, enynones were selectively transformed through [3+2] cycloadditions to give oxabicycles 2 in the presence of [L3AuCl] (L3=[tris(para‐trifluoromethylphenyl)phosphine], 5 mol %). When [L2(CNCH3)Au]SbF6 (L2=[2‐(di‐tert‐butylphosphino)biphenyl]) was used as the catalyst, the [4+2] cycloaddition naphthyl ketone products dihydrobenzo[f]isoquinolines 3 were obtained. The value of this method is indicated by the applicability of various enynones substrates and the highly regioselective synthesis of two potentially useful polycyclic compounds.
The risk of tuberculosis transmission to free‐ranging great apes
Authors: Wolf Tiffany M. , Sreevatsan Srinand , Travis Dominic , Mugisha Lawrence , Singer Randall S.
Published: September 2013

Pathogen exchange between humans and primates has been facilitated by anthropogenic disturbances, such as changing land use patterns, habitat destruction, and poaching, which decrease population sizes and increase levels of primate–human interaction. As a result, human and domestic animal diseases have become a recognized threat to endangered primate populations. Tuberculosis is a major global human and animal health concern, especially in equatorial Africa where many of the remaining free‐living great ape populations exist in proximity with exposed and/or infected human populations and their domestic animals. Increased anthropogenic pressure creates an opportunity for the anthropozoonotic spread of this disease. This review examines current evidence of the risk of tuberculosis transmission to great apes, the benefits and limitations of current detection methods, the impact of current great ape conservation and management strategies on this risk, and the need for an ecosystem health‐based approach to mitigating the risks of tuberculosis transmission to great apes. Am. J. Primatol. 76:2–13, 2014. © 2013 Wiley Periodicals, Inc.
Electropreparation of (±)‐10‐camphorsulfonate‐doped poly(o‐phenylenediamine) in acetonitrile and its use in determination of glucose
Authors: Zeybek Bülent , Pekmez Nuran Özçiçek , Kılıç Esma
Published: September 2013

Poly(o‐phenylenediamine) (PoPD) film has been electrochemically prepared on Pt electrode in an acetonitrile–water medium containing o‐phenylenediamine (oPD) monomer and (±)‐10‐camphorsulfonic acid (HCSA) by using the cyclic voltammetry (CV). The PoPD film (PoPD–CSA) has been characterized by FTIR, CV, EIS, FESEM, and conductivity measurement. The glucose biosensor (Pt/PoPD–CSA/GOx) has been prepared from the PoPD coated electrode by immobilizing glucose oxidase (GOx) enzyme using glutaraldehyde. The biosensor shows a low detection limit and wide linear working range, a good reusability, long‐term stability, and anti‐interference ability. The Pt/PoPD–CSA/GOx has possesses higher sensitivity (2.05 μA/mmol L−1) and affinity to glucose due to the use of CSA ion as dopant. The linear concentration ranges of Pt/PoPD–CSA/GOx have been found to be 9.6 × 10−3 to 8.2 mmol L−1 from calibration curve and 4.6 × 10−2 to 100 mmol L−1 from the relationship between the (1/glucose concentration) and (1/current difference). © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 39864.
An Adaptive and Optimized Switching Observer for Sensorless Control of an Electromagnetic Valve Actuator in Camless Internal Combustion Engines
Authors: Mercorelli Paolo
Published: September 2013

In this paper, the design and operation of a special electromagnetic actuator as a variable engine valve actuator are presented. Further, this paper describes a feasible approximated velocity switching estimator based on measurements of current and input voltage to achieve sensorless control. The proposed concept allows a reduced‐order observer to be conceived and yields a specific control strategy with an acceptable performance. In general, this approach represents a viable strategy to build reduced‐order observers for estimating the velocity of systems through the measurement of input current and voltage. The robustness of the velocity tracking is explored using a minimum variance approach. The effect of the noise is minimized, and the position can be achieved through an adaptive and optimized structure by combining this particular velocity estimator and an observer based on the electromechanical system. Position control is achieved through an inversion of the model. This approach avoids a more complex structure for the observer and yields an acceptable performance as well as eliminating bulky position‐sensor systems. In addition, a control strategy is presented and discussed. Computer simulations of the sensorless control structure are presented in which the positive effects of the observer with optimized parameter setting are visible in the closed‐loop control.
Pharmacokinetic study of amoxicillin in human plasma by solid‐phase microextraction followed by high‐performance liquid chromatography–triple quadrupole mass spectrometry
Authors: Szultka Malgorzata , Krzeminski Rafal , Walczak Justyna , Jackowski Marek , Buszewski Boguslaw
Published: September 2013

Sensitive and selective analytical procedures based on high‐performance liquid chromatography with mass spectrometric detection were developed for the determination of amoxicillin in human plasma samples. Samples were prepared by applying in‐house manufactured molecularly imprinted solid‐phase microextraction probes. The detection of target compounds was performed in multiple reaction monitoring mode. The multiple reaction monitoring detection was operated in the positive electrospray ionization mode using the transitions of m/z 366 ([M + H]+) → 349 for amoxicillin and m/z 390 ([M + H]+) → 372 for gemifloxacin. The method was validated with precision within 15% relative standard deviation and accuracy within 15% relative error. The method was successfully applied to study of the pharmacokinetics of amoxicillin in human plasma after oral administration of amoxicillin. Copyright © 2013 John Wiley & Sons, Ltd.
Silicon‐Rich Carbon Hybrid Nanofibers from Water‐Based Spinning: The Synergy Between Silicon and Carbon for Li‐ion Battery Anode Application
Authors: Kim Yong Seok , Kim Kyung Woo , Cho Daehwan , Hansen Nathaniel S. , Lee Jinwoo , Joo Yong Lak
Published: September 2013

Hybrid carbon nanofibers (NFs) with extremely high Si loading (>65 wt %) are fabricated through the water‐based electrospinning of polyvinyl alcohol/Si nanoparticle (NP) solutions for Li‐ion battery anode applications. Our Si‐rich carbon (SRC) NFs show many facilitated charge‐transport features and increased activities because of the continuous one‐dimensional (1D) carbon backbone structure with dispersed Si NP domains. This leads to superior battery performance compared to that of bare silicon NPs. The presence of carbon as 1D NFs can not only mitigate the volume change of silicon but also avoid the formation of an unstable solid‐electrolyte interface on the surface of silicon. Our study, regarding the optimum combination of C and Si in the NFs for their improved electrochemical properties and battery performance, reveals that SRC NFs containing 72.8 wt % Si (27.2 wt % C) exhibit an adequate balance between the high energy capacity of Si NPs and the dimensional stability and effective charge transport of carbon NFs. This optimum Si/C ratio leads to an outstanding cycle life, which maintains 1076 mAh g−1 capacity normalized by the total electrode mass, and a Coulombic efficiency of about 99 % over 50 cycles. Such scalable SRC NFs produced through the water‐based spinning approach can offer a cost‐effective development for high‐performance battery anodes.
Mechanistic Investigations into the Enantioselective Conia‐Ene Reaction Catalyzed by Cinchona‐Derived Amino Urea Pre‐Catalysts and CuI
Authors: Sladojevich Filippo , Fuentes de Arriba Ángel L. , Ortín Irene , Yang Ting , Ferrali Alessandro , Paton Robert S. , Dixon Darren J.
Published: September 2013

The enantioselective Conia‐ene cyclization of alkyne‐tethered β‐ketoesters is efficiently catalyzed by the combination of cinchona‐derived amino‐urea pre‐catalysts and copper(I) salts. The reaction scope is broad and a series of substrates can be efficiently cyclized with high yields and enantioselectivities. Herein, we present a detailed mechanistic study based on experimental considerations and quantum mechanical calculations. Several variables, such as the nature of the organic pre‐catalyst and the metal‐ion source, have been thoroughly investigated. Kinetic studies, as well as kinetic isotope effects and deuterium labeling experiments have been used to gain further insights into the mechanism and prove the cooperative nature of the catalytic system. Our studies suggest that the rate‐limiting step for the reaction involves the β‐ketoester deprotonation and that the active species responsible for the enantiodeterming step is monomeric in amino‐urea pre‐catalyst. Computational studies provide a quantitative understanding of the observed stereoinduction and identify hydrogen bonding from the urea group as a crucial factor in determining the observed enantioselectivity.
Fluorinated and Trifluoromethylated Corannulenes
Authors: Schmidt Bernd M. , Topolinski Berit , Yamada Mihoko , Higashibayashi Shuhei , Shionoya Mitsuhiko , Sakurai Hidehiro , Lentz Dieter
Published: September 2013

The syntheses and properties of corannulenes carrying electron‐withdrawing groups (F, CF3, C6F5) are reported. Direct fluorination of corannulene (C20H10) was carried out with xenon difluoride, and the crystal structure of the product was confirmed by the X‐ray analysis. Novel trifluoromethylated corannulenes, including the versatile 4,9‐dibromo‐1,2‐bis(trifluoromethyl)corannulene, were obtained by various established ring‐closing reactions. Besides the use of hexafluorobutyne for the construction of fluoranthenes by Diels–Alder reaction as precursor molecules to form 1,2‐disubstituted corannulenes, bis(pentafluorophenyl)acetylene was employed as dienophile. The molecular structure and crystal packing of a trifluoromethylated corannulene was determined by single‐crystal X‐ray analysis and compared with those known brominated and trifluoromethylated corannulenes. The general electron‐acceptor properties of corannulenes bearing substituents introduced in particular positions by liquid‐phase synthesis are discussed together with published computational results.
ChemInform Abstract: Effect of Ti Co‐Doping on Photoluminescence Characteristics of Eu:BaAl2O4.
Authors: Ryu H. , Bartwal K. S.
Published: September 2013

BaAl2O4:Eu2+, Ti3+ samples are prepared by solid‐state reaction of the corresponding oxides in stoichiometric ratios with a 1 mol% fixed Eu content and Ti co‐dopant levels of 1, 2, and 3 mol% (1.
ChemInform Abstract: Sustainable Preparation of Li(FeM)PO4/C from Converter Sludge and Its Electrochemical Performance as a Cathode Material for Lithium Ion Batteries.
Authors: Zhang Zhong‐Fang , Wu Zhao‐Jin , Su Shi‐Huai , Gao Zhi‐Fang , Li Liao‐Sha , Wu Xing‐Rong
Published: September 2013

Li(Fe,M)PO4/C (M: Mg, Al, Zn, Mn) cathode materials for lithium ion batteries are prepared by addition of H3PO4, H2O2, and NH4OH to aqueous H2SO4 solutions of converter sludge (pH 4, 45 min), followed by sintering a mixture of the obtained (Fe,M)PO4, LiOH·H2O, and polypropylene at 710 °C for 8 h.
ChemInform Abstract: Synergistic Effect of SnO2/ZnWO4 Core—Shell Nanorods with High Reversible Lithium Storage Capacity.
Authors: Xing Li‐Li , Yuan Shuang , He Bin , Zhao Ya‐Yu , Wu Xiao‐Ling , Xue Xin‐Yu
Published: September 2013

SnO2/ZnWO4 core—shell nanorods are prepared by a two‐step method.
ChemInform Abstract: A Mild Chemoselective Ru‐Catalyzed Reduction of Alkynes, Ketones, and Nitro Compounds.
Authors: Schabel Tobias , Belger Christian , Plietker Bernd
Published: September 2013

The particular protocols for reduction of functional groups allow selective transformations in presence of different reducible moieties.
ChemInform Abstract: Pauson—Khand Adducts of N‐Boc‐propargylamine: A New Approach to 4,5‐Disubstituted Cyclopentenones.
Authors: Aiguabella Nuria , Pesquer Albert , Verdaguer Xavier , Riera Antoni
Published: September 2013

This protocol is based on the Pauson—Khand reaction of alkynes and norbornadiene yielding masked cyclopentadienones with a readily functionalizable double bond.
ChemInform Abstract: A Convenient Method for the Synthesis of Allenoates from 4‐Hydroxyalk‐2‐ynoates with PPh3.
Authors: Kim Hyuna , Jin Kyung Yong , Ha Tae Hee , Yu Chan‐Mo
Published: September 2013

This practical and convenient method to synthesize allenoates is only applicable to acyclic substrates.
ChemInform Abstract: BINAM‐mono‐PHOS as New Entry for Multinuclear Copper Catalysts in Asymmetric Conjugate Addition of Organozinc Reagents.
Authors: Endo Kohei , Takayama Ryotaro , Shibata Takanori
Published: September 2013

Among a large variety of binaphthyl compounds evaluated as chiral ligands, high yields and enantioselectivities are achieved with (Ia) for the addition of ZnEt2.
ChemInform Abstract: Simple and Efficient Procedure for Synthesis of N′‐Arylamidines Using Trimethylaluminum.
Authors: Korbad Balaji L. , Lee Sang‐Hyeup
Published: September 2013

A simple and efficient method for the synthesis of N′‐arylamides (III) from various aliphatic and aromatic nitriles and a variety of aromatic amines under mild conditions is presented.
ChemInform Abstract: Catalytic, Enantioselective, Intramolecular Carbosulfenylation of Olefins.
Authors: Denmark Scott E. , Jaunet Alex
Published: September 2013

For the first time a catalytic enantioselective carbosulfenylation of alkenes with an aromatic nucleophile is presented.
ChemInform Abstract: A Highly Efficient Protocol for the Regio‐ and Stereoselective Synthesis of Spiro Pyrrolidine and Pyrrolizidine Derivatives by Multicomponent Reaction.
Authors: Dandia Anshu , Jain Anuj K. , Laxkar Ashok K. , Bhati Dharmendra S.
Published: September 2013

Azomethine ylides, generated in situ from ketones (I) and (VIII) and amino acids, undergo 1,3‐dipolar cycloaddition with alkenes to form a broad spectrum of the pharmaceutically important heterocyclic scaffolds.
ChemInform Abstract: Synthesis and Cycloaddition Chemistry of Oxetanyl‐Substituted Sydnones.
Authors: Nassoy Anne‐Chloe , Raubo Piotr , Harrity Joseph P. A.
Published: September 2013

Title compounds (III) are prepared by magnesiation of 4‐unsubstituted sydnones followed by reaction with oxetan‐3‐one.
ChemInform Abstract: An Organocatalytic Approach to Stereoselective Synthesis of 2‐Hydroxyazetidines and 2‐Hydroxypyrrolidines.
Authors: Rai Ankita , Yadav Lal Dhar S.
Published: September 2013

Chiral enamines derived from aldehydes and PRS undergo Mannich‐type reaction with imines and aziridines followed by intramolecular hemiaminalization to afford the title heterocycles with complete diastereoselectivity.
ChemInform Abstract: P‐Spiro Phosphonium Salts Catalyzed Asymmetric Fluorination of 3‐Substituted Benzofuran‐2(3H)‐ones.
Authors: Zhu Chuan‐Le , Fu Xiao‐Yun , Wei Ai‐Jia , Cahard Dominique , Ma Jun‐An
Published: September 2013

The (S,S)‐isomer of the depicted phosphonium salt is capable of catalyzing the title reaction with excellent yields and low to moderate enantioselectivities.
ChemInform Abstract: An Efficient Synthesis of β,γ,γ‐Trisubstituted‐α‐diethoxyphosphoryl‐γ ‐lactams: A Convenient Approach to α‐Methylene‐γ‐lactams.
Authors: Deredas Dariusz , Albrecht Lukasz , Krawczyk Henryk
Published: September 2013

The synthesis of title compounds (III) is achieved in a single step through tetramethylguanidine‐promoted Michael addition of malonate (II) to acrylates (I) followed by spontaneous lactamization and acylation.
ChemInform Abstract: Symmetric and Unsymmetric 3,3′‐Linked Bispyrroles via Ring‐Enlargement Reactions of Furan‐Derived Donor—Acceptor Cyclopropanes.
Authors: Kaschel Johannes , Schneider Tobias F. , Kratzert Daniel , Stalke Dietmar , Werz Daniel B.
Published: September 2013

A synthetic route has been developed to access symmetrically and unsymmetrically substituted 3,3′‐linked bispyrroles by making use of the special features of furan‐derived donor‐acceptor cyclopropanes.
ChemInform Abstract: Three‐Component Synthesis of Poly‐Substituted Tetrahydroindoles Through p‐TsOH Promoted Alkoxylation.
Authors: Shi Qing‐Qing , Fu Li‐Ping , Shi Yu , Ding Hua‐Qin , Luo Jing‐Hua , Jiang Bo , Tu Shu‐Jiang
Published: September 2013

Optimized conditions allow a sequential alkoxylation/heterocyclization of arylglyoxal monohydrates, alcohols and enaminones to produce the title species in a short reaction time.
ChemInform Abstract: Synthesis and Anticancer Activity of New Substituted Pyrazoles and Their Derived 1,2,4‐Triazoles and Sugar Derivatives.
Authors: Flefel Eman M. , Tantawy Waled A. , El‐Sayed Wael A. , Sayed Hayam H. , Fathy Nahed M.
Published: September 2013

Various title compounds are prepared and tested for their antitumor activities.
ChemInform Abstract: Synthesis of Substituted Hydantoins in Low Melting Mixtures.
Authors: Gore Sangram , Chinthapally Kiran , Baskaran Sundarababu , Koenig Burkhard
Published: September 2013

Unsaturated ketoacids (I) are readily converted into functionalized hydantoins (III) in a low melting mixture of N,N′‐dimethylurea and L‐tartaric acid.
ChemInform Abstract: Synthesis and Properties of 1‐(2‐(Alkylamino)‐2‐oxoethyl) Pyridinium Chloride Surfactants.
Authors: Wang Li‐yan , Qin Hong‐lei , Wang Lei , Huo Shi‐chao , Zhao Bing , Song Bo , Yan Tie
Published: September 2013

The synthesized surfactants (V) show good antibacterial activities against sulfate‐reducing bacteria, metatrophic bacteria and iron bacteria in oil field injection water.
ChemInform Abstract: Regiospecific 6‐endo‐Annulation of in situ Generated 3,4‐Dienamides/Acids: Synthesis of δ‐Lactams and δ‐Lactones.
Authors: Liu Ying , Barry Badru‐Deen , Yu Haifeng , Liu Jianquan , Liao Peiqiu , Bi Xihe
Published: September 2013

A novel and efficient method for the construction of α‐(1,3‐dithiolan‐2‐ylidene) δ‐lactams (III) and δ‐lactones (V) is developed.
ChemInform Abstract: A Highly Efficient and Selective Aerobic Cross‐Dehydrogenative‐Coupling Reaction Photocatalyzed by a Platinum(II) Terpyridyl Complex.
Authors: Zhong Jian‐Ji , Meng Qing‐Yuan , Wang Ge‐Xia , Liu Qiang , Chen Bin , Feng Ke , Tung Chen‐Ho , Wu Li‐Zhu
Published: September 2013

The title reaction affords the desired coupling products within a short reaction time under ambient air conditions.
ChemInform Abstract: A Green Synthesis of Quinoxalines and 2,3‐Dihydropyrazines.
Authors: Delpivo Camilla , Micheletti Gabriele , Boga Carla
Published: September 2013

Various 1,2‐diamines react with 1,2‐dicarbonyl compounds in water in the absence of any catalyst to give the desired heterocyclic systems.
ChemInform Abstract: Electrophilic Cyclization of N‐Alkynyl‐2‐(organochalcogen)imidazoles: An Alternative Access to Imidazo[2,1‐b]chalcogenazoles.
Authors: Grimaldi Tamiris B. , Godoi Benhur , Roehrs Juliano A. , Speranca Adriane , Zeni Gilson
Published: September 2013

An electrophilic title cyclization reaction allows the selective synthesis of 3‐iodoimidazoselenazoles [cf.
ChemInform Abstract: Reaction of Selenium Dichloride with Acrylic Acid and Its Derivatives. Regioselective Synthesis of New Functionalized Selenides.
Authors: Potapov V. A. , Khabibulina A. G. , Albanov A. I. , Amosova S. V.
Published: September 2013

The reaction of selenium dichloride, which can be prepared in situ from selenium and sulfuryl chloride, with acrylic acid (IIa), ethyl acrylate (IIb), or acrylonitrile at ‐20°C gives the corresponding selenides (II) in high yields.
ChemInform Abstract: Study on Synthesis of 2‐(Substituted benzylidene) amino‐2‐deoxy‐1,3,4,6‐tetra‐O‐acetyl‐β‐D‐glucopyranones from D‐Glucosamine.
Authors: Nguyen Dinh Thanh , Nguyen Van Quoc
Published: September 2013

The title compounds (III) are obtained in reactions of α‐D‐glucosamine hydrochloride with different substituted benzaldehydes under optimized reaction conditions.
ChemInform Abstract: Cytotoxic Azaphilone Alkaloids from Chaetomium globosum TY1.
Authors: Li Xiang , Tian Ye , Yang Sheng‐xiang , Zhang Ya‐mei , Qin Jian‐chun
Published: September 2013

Three novel azaphilone alkaloids, chaetomugilides A—C, are isolated together with three related compounds.
ChemInform Abstract: Facile Syntheses of Novel Salts of a Triazole Antifungal Agent with Enhanced Solubility.
Authors: Kumar Neeraj , Shishu Shishu , Kapoor Rishi
Published: September 2013

Nitric, sulfuric, and p‐toluenesulfonic acid addition salts of itraconazole are prepared to enhance the aqueous solubility and dissolution characteristics of the drug.
ChemInform Abstract: Porous Texture Versus Surface Chemistry in Applications of Adsorption by Carbons
Authors: Figueiredo Jose Luis , Pereira Manuel Fernando R.
Published: September 2013

Review: 84 refs.
ChemInform Abstract: Crystallographic and Structural Characterization of Heterometallic Platinum Compounds. Part 2. Heterobinuclear Pt Compounds with Pt···M (M: Transition or Lanthanide Metal) < 3.0 Å
Authors: Melnik Milan , Sprusansky Ondrej , Holloway Clive E.
Published: September 2013

Review: 192 refs.
ChemInform Abstract: Ge1‐xMnx‐Diluted Magnetic Semiconductor Nanostructures for Spintronics
Authors: Wang Yong , Xiu Faxian , Zou Jin , Wang Kang L.
Published: September 2013

Review: emphasis on the growth and structural properties of Ge:Mn thin films and quantm dots; 50 refs.
ChemInform Abstract: Combination Control, Nanomagnetism, and Biomedical Applications of Inorganic Multicomponent Hybrid Nanomaterials
Authors: Zhang Haitao , Ding Jun , Chen Xianhui , Zhang Hailang , Liu Xiaohe
Published: September 2013

Review: 25 refs.
ChemInform Abstract: Porous Coordination Polymers Constructed from Anisotropic Metal‐carboxylate‐pyridyl Clusters
Authors: Zhang Yue‐Biao , Zhang Jie‐Peng
Published: September 2013

Review: 45 refs.
ChemInform Abstract: Recent Progress in the Chemistry of Organic Functional Radicals
Authors: Nakatsuji Shin'ichi
Published: September 2013

Review: 21 refs.
ChemInform Abstract: Chemistry Computationally and Experimentally: How Will Computational Organic Chemistry Impact Organic Theories, Mechanisms, and Synthesis in the Twenty‐first Century?
Authors: Yu Zhi‐Xiang , Liang Yong
Published: September 2013

Review: 121 refs.
ChemInform Abstract: Catalytic Appel Reactions
Authors: van Kalkeren Henri A. , van Delft Floris L. , Rutjes Floris P. J. T.
Published: September 2013

Review: progress in developing and utilizing new organophosphorus catalysts, especialldibenzophospholes, 80 refs.
ChemInform Abstract: Highly Selective Introduction of Heteroatom Groups to Isocyanides and Its Application to Electrocyclic Reactions
Authors: Ogawa Akiya , Tamai Taichi , Mitamura Takenori , Nomoto Akihiro
Published: September 2013

Review: 34 refs.
ChemInform Abstract: Metal‐Free Catalytic Vicinal Diamination of Alkenes
Authors: Muniz Kilian
Published: September 2013

Review: 46 refs.
ChemInform Abstract: Transition Metal‐Catalyzed Efficient and Green Transformations of P(O)‐H Compounds to Functional Organophosphorus Compounds
Authors: Xu Qing , Zhou Yong‐Bo , Zhao Chang‐Qiu , Yin Shuang‐Feng , Han Li‐Biao
Published: September 2013

Review: 105 refs.
ChemInform Abstract: Organic Selenium Resin in Solid Phase Synthesis and Its Application in Constructing Medicinally Relevant Small Organic Molecules
Authors: Li Qing‐Si , Wu Dong‐Mei , Zhu Bing‐Chun , Wang Yu‐Guang
Published: September 2013

Review: 94 refs.
ChemInform Abstract: Total Synthesis of the Myxobacterial Macrolide Ripostatin B
Authors: Glaus Florian , Altmann Karl‐Heinz
Published: September 2013

Review: 34 refs.
ChemInform Abstract: Synthesis of Diversely Fluorinated Pyrazoles as Novel Active Agrochemical Ingredients
Authors: Giornal Florence , Pazenok Sergiy , Rodefeld Lars , Lui Norbert , Vors Jean‐Pierre , Leroux Frederic R.
Published: September 2013

Review: 50 refs.
ChemInform Abstract: The Structural Basis of G‐Protein‐Coupled Receptor Signaling (Nobel Lecture).
Authors: Kobilka Brian
Published: September 2013

Review: 51 refs.
ChemInform Abstract: Recent Developments on the Mechanism and Kinetics of Esterification Reaction Promoted by Various Catalysts
Authors: Zeng Zuoxiang , Cui Li , Xue Weilan , Chen Jing , Che Yu
Published: September 2013

Review: 87 refs.
ChemInform Abstract: Progress in Electron Tomography to Assess the 3D Nanostructure of Catalysts
Authors: Zecevic Jovana , de Jong Krijn P. , de Jongh Petra E.
Published: September 2013

Review: 78 refs.
Calibration of the X‐Ray Photoelectron Spectroscopy Binding Energy Scale for the Characterization of Heterogeneous Catalysts: Is Everything Really under Control?
Authors: Jacquemin Marc , Genet Michel J. , Gaigneaux Eric M. , Debecker Damien P.
Published: September 2013

Investigations of X‐ray photoelectron spectra from solid samples need corrections for the surface charging effect. For powder samples such as heterogeneous catalysts and their supports, the C(C,H) component of the C 1s peak is often used as an internal standard for the calibration of the binding energy scale. Although this method is widely recognized as suitable for the study of heterogeneous catalysts, we show that a significant calibration bias can be encountered upon comparing samples with different bulk composition. In this paper, a series of SiO2–Al2O3 supports and Pd/SiO2–Al2O3 catalysts with various Si/Al ratios were studied. The spectra issued from these samples were processed with the classical calibration method on the basis of the carbon peak. Important discrepancies in the relative position of the photoelectron peaks were noticed. After systematically discarding instrument‐related issues, a true chemical influence of the bulk matrix on the analyzed surface species was evidenced. The extent of this chemical effect was dependent on the composition of the sample and more precisely on its ionicity. Two possible mechanisms for this chemical effect were proposed and discussed. Finally, an alternative calibration method was offered.
Durable Superhydrophobic Surfaces Prepared by Spray Coating of Polymerized Organosilane/Attapulgite Nanocomposites
Authors: Li Bucheng , Zhang Junping , Wu Lei , Wang Aiqin
Published: September 2013

Complicated and expensive preparation methods and the low stability of most superhydrophobic surfaces are the bottlenecks that must be faced for their practical application. Herein, a simple and low‐cost approach for preparing durable superhydrophobic surfaces by spray coating of polymerized organosilane/attapulgite (POS/APT) nanocomposites is reported. The POS/APT nanocomposites were prepared by condensation of hexadecyltriethoxysilane and tetraethoxysilane in the presence of APT through a modified Stöber method. The morphology and content of clay minerals have great influence on the superhydrophobicity. Only rodlike APT with a weight ratio of APT to organosilanes not less than 0.60 can form the superhydrophobic surfaces. The POS/APT superhydrophobic surfaces feature high water contact angle (CA≈160°), low sliding angle (SA≈2°), excellent stability, and good transparency. A spray coating density as low as 5 g m−2 is enough to obtain the superhydrophobic properties. The cost of such a coating is approximately 4 RMB m−2. The POS/APT surfaces are stable towards sand abrasion, water pressure, harsh temperature, UV irradiation, and solvent immersion. In addition, a slightly damaged surface can be readily repaired by spray coating again according to the same procedure. Moreover, the durable POS/APT superhydrophobic coatings are applicable to various substrates (e.g., polyurethane plate, paper, and polyester textile) and can be easily scaled up.
Modular Synthesis of Optically Active Tröger’s Base Analogues
Authors: Kamiyama Takuya , Özer Merve Sinem , Otth Elisabeth , Deska Jan , Cvengroš Ján
Published: September 2013

For the first time, enantioselective catalysis was applied for the preparation of Tröger’s base derivatives affording N‐stereogenic building blocks not only in excellent enantiomeric purity but also in an easily scalable fashion. Enzymatic kinetic resolution proved efficient to yield functionalized Tröger’s bases, which can be subsequently modified by various chemical methods without any erosion of stereogenic information. In concert with a preparatively convenient protocol for the synthesis of the racemic substrates from commercially available anilines, a highly practicable and flexible route towards a wide range of enantiopure Tröger’s base analogues is provided.
Manganese‐Catalyzed Selective Oxidation of Aliphatic CH groups and Secondary Alcohols to Ketones with Hydrogen Peroxide
Authors: Dong Jia Jia , Unjaroen Duenpen , Mecozzi Francesco , Harvey Emma C. , Saisaha Pattama , Pijper Dirk , de Boer Johannes W. , Alsters Paul , Feringa Ben L. , Browne Wesley R.
Published: September 2013

An efficient and simple method for selective oxidation of secondary alcohols and oxidation of alkanes to ketones is reported. An in situ prepared catalyst is employed based on manganese(II) salts, pyridine‐2‐carboxylic acid, and butanedione, which provides good‐to‐excellent conversions and yields with high turnover numbers (up to 10 000) with H2O2 as oxidant at ambient temperatures. In substrates bearing multiple alcohol groups, secondary alcohols are converted to ketones selectively and, in general, benzyl CH oxidation proceeds in preference to aliphatic CH oxidation.
Does polyomavirus infection interfere with bladder cancer fluorescence in situ hybridization?
Authors: Hossain Deloar , Hull David , Kalantarpour Fatemeh , Maitlen Rebecca , Qian Junqi , Bostwick David G.
Published: September 2013

Urine cytology is a proven and widely used screening tool for the detection of urothelial carcinoma. However, morphologic features of polyomavirus infected cells, characterized by nuclear inclusions (decoy cells) are a known source of diagnostic confusion with malignancy. Fluorescence in situ hybridization (FISH) is now routinely used to support the cytological diagnosis of urothelial carcinoma and monitor for recurrence. We sought to determine whether polyomavirus infection could result in positive FISH results (aneuploidy).

This study deals with retrospective study of 100 polyomavirus‐infected urine samples from patients with no history of urothelial carcinoma or organ transplantation. All cases were stained with Papanicolaou and acid hematoxylin stain. One slide from each sample was de‐stained and FISH was performed using chromosome enumeration probes 3, 7, 17, and locus‐specific probe 9p21.

Adequate cells for FISH analysis (25 cells) were present in 81 cases; 19 cases were insufficient due to loss of cells during de‐staining and FISH preparation process. All polyomavirus‐infected cells (decoy cells) exhibited a normal chromosome pattern. Four cases were FISH positive, but there were no positive decoy cells.

Decoy cells did not exhibit aneuploidy by FISH. The presence of decoy cells does not exclude the possibility of concurrent urothelial carcinoma. Acid hematoxylin stain appeared to supplement the Papanicolou stain in identifying and confirming the presence of polyomavirus infection. Diagn. Cytopathol. 2014;42:225–229. © 2013 Wiley Periodicals, Inc.