bluuebunny/crossref_metadata_2025 huggingface dataset:
Mapping the health systems response to violence against women:
Authors: Sikder Shegufta Shefa , Ghoshal Rakhi , Deosthali Padma , Jaishwal Chandni , Roy Nobhojit
Published: February 2021

Background: Violence against women (VAW) is prevalent globally, and the health sector is a key entry point for survivors to receive care. However, documentation on the rollout of health system response to violence against women is lacking in low and middle-income countries. This paper maps the operationalization of health systems response to violence against women in five low- and middle-income countries (LMIC) to identify core learnings. Methods: We selected five LMIC contexts that were actively addressing national-level health system response from 2015 to 2020 and where we had access to practitioners directly engaged in national rollout. We synthesized publicly available data and program reports according to the components of the Health Systems Framework to Address VAW. Results: One-stop centers were found to be the dominant model of care located in hospitals implemented by the health systems in four countries except Brazil, where one-stop centers are not located in hospitals and do not provide health services. While each setting has implemented in-service training as key to addressing provider knowledge, attitudes and practice, significant gaps remain in addressing frequent staff turnover, provision of training at scale, and documentation on the impact of training. Health system protocols for VAW address sexual violence but do not uniformly include clinical and health policy responses for other forms of violence. In Brazil, Nepal, and Sri Lanka, harmful practices such as virginity testing remain within clinical protocols. Providing privacy to survivors within health facilities was a universal challenge. Conclusions: Significant efforts have been made to address provider attitudes towards provision of care and in protocolized delivery of care to survivors, primarily through one-stop centers. Improvements can be made in data collection on training impact on provider attitudes and practices, in provider identification of VAW survivors, and in prioritization of VAW within health system budgeting, staffing, and political priorities. Beyond hospital-based one-stop centers at tertiary and district levels, primary health facilities need to provide first-line support for survivors to avoid delays in response to VAW as well as for secondary prevention.
Thematic direction of travel media
Authors: Shevchenko Viktoriya , Malysh Nataliia
Published: February 2021

The article categorizes travel media, describes their features, outlines the tools of communication of media resources related to tourism development, and substantiates the impact of travel journalism on the cultural development of the nation. The purpose of the article is to classify travel media and identify thematic, trends in the formation and development of tourism journalism in Ukraine. Thematic blocks of travel media that influence the formation of cultural consciousness of Ukrainian citizens with the use of content analysis and statistical research methods are identified. The analysis of more than 50 Ukrainian tourist media made it possible to distinguish the following topics: country studies, tips, lifestyle, art, nature and ecology, iconic figures, tourist infrastructure, marketing and trends, tourism development.
Design and development children’s cross-tv
Authors: Leontieva Tetiana
Published: February 2021

The phenomenon of children’s cross-television is analyzed. It is alleged that cross-television uses Internet platforms to introduce content – in this case, children’s. It is emphasized that the communication capabilities of modern Internet platforms can turn the content of traditional children’s television into the attractive game or educational content that will interest the child primarily because it contains an interesting form of teaching useful content. The essence and features of the presentation of television technologies for children, as well as the positive and negative consequences of the use of cross-TV content by children’s audience, are analyzed.
On the stability of the infinite Projected Entangled Pair Operator ansatz for driven-dissipative 2D lattices
Authors: Kilda Dainius , Biella Alberto , Schirò Marco , Fazio Rosario , Keeling Jonathan
Published: February 2021

We present calculations of the time-evolution of the driven-dissipative XYZ model using the infinite Projected Entangled Pair Operator (iPEPO) method, introduced by [A. Kshetrimayum, H. Weimer and R. Orús, Nat. Commun. 8, 1291 (2017)].
We explore the conditions under which this approach reaches a steady state. In particular, we study the conditions where apparently converged calculations may become unstable with increasing bond dimension of the tensor-network ansatz. We discuss how more reliable results could be obtained.
FEIRA DE CIÊNCIAS: ABORDANDO RELAÇÕES ENTRE TERMODINÂMICA E CORPO HUMANO
Authors: Puhl Neiva Mara , Marchi Miriam Ines
Published: February 2021

As feiras de ciências, bastante populares no Brasil, são vistas como uma oportunidade para que estudantes tanto do Ensino Fundamental como do Ensino Médio, possam apresentar suas produções científicas. O trabalho tem como objetivo averiguar as contribuições da feira de ciências na construção e reconstrução de conhecimento bem como avaliar indícios de autonomia dos estudantes mediante os trabalhos apresentados. Neste sentido, o estudo é um recorte de uma das atividades, desenvolvida com alunos do 2º ano do Ensino Médio de uma escola pública, localizada no município de Sinop/MT, durante a intervenção pedagógica de uma mestranda de um Mestrado Profissional em Ensino de Ciências Exatas. Os estudantes foram avaliados pela pesquisadora levando em consideração, além dos itens exigidos no roteiro, a qualidade do trabalho exposto, a relevância das informações apresentadas sobre o tema, a criatividade, o planejamento e a apresentação de material extra. Além dessa avaliação, também ocorreu avaliação por um grupo de professores convidados pela comissão organizadora do evento. A feira de ciências possibilitou uma melhor compreensão dos conteúdos abordados durante a intervenção. Além disso, contribui para  autonomia dos estudantes na busca de novos conhecimentos, serviu também,  como um indicativo de que o conhecimento nunca está pronto e acabado.
A LÍNGUA QUE A ESCOLA COMEU
Authors: Wayhs Mariana De Oliveira , Dorneles Elizabeth Fontoura
Published: February 2021

A constituição do sujeito criança na relação com a personagem Bruxa dos contos de fadas é o tema deste estudo. O objetivo central da pesquisa é desvelar o funcionamento discursivo a partir da análise dos efeitos de sentido constituídos na relação personagem Bruxa / sujeito criança e os impactos em termos de linguagem e comunicação. A materialidade de análise consta de entrevista semiestruturada com crianças de 6 a 11 anos, filhos dos catadores do Projeto Profissão Catador da UNICRUZ, gravação dos áudios e transcrição, para a formação do arquivo do analista. Partindo das sequências discursivas selecionadas, são aplicados os procedimentos teórico-metodológicos da Análise de Discurso Francesa (AD). Ao aprofundarmos os estudos discursivos percebemos que a Bruxa inscrita nas condições de produção das crianças entrevistadas é a da inquisição, a demoníaca, que, na realidade, acaba se materializando no silenciamento do sujeito criança, consequência do trabalho com a língua portuguesa a partir de uma perspectiva imaginária, e não fluida.

Palavras-chave: Análise do discurso. Efeito Bruxa. Cultura. Sociedade moderna. Criança.
TECNOLOGIAS MÓVEIS NA EDUCAÇÃO: UM PROJETO COM TABLETS NA ESCOLA PÚBLICA
Authors: Damasceno Handherson Leyltton Costa , Neves Barbara Coelho
Published: February 2021

O objetivo do artigo é analisar o processo de implementação do projeto 'Tecnologias Móveis: inserção dos tablets na educação' em duas escolas públicas da rede municipal de Educação de Salvador, Bahia. Utilizamos a abordagem qualitativa, o método descritivo, a metodologia de pesquisa de campo e como técnica de observação, a entrevista. Colaboraram como sujeitos da pesquisa oito indivíduos e os dados foram avaliados sob a orientação da análise de conteúdo. Como resultados, três eixos emergiram das entrevistas: a. Elementos descritivos do projeto; b. O tablet na sala de aula e c. Avaliação do projeto. As análises destacam a importância do protagonismo do professor e do aluno. O estudo considera que o projeto foi importante para a aprendizagem dos estudantes, mas a infraestrutura adequada para a sua realização foi precária e precisa ser melhorada e ampliada.
SENSIBILIZAR PARA INCLUIR: VOVÓ FOFUXA E SUAS BONECAS DE PANO NA EDUCAÇÃO INFANTIL E ENSINO FUNDAMENTAL I
Authors: Torres Eloiza Cristiane , Veiga Léia Aparecida
Published: February 2021

É cada vez mais comum a presença de estudantes com deficiência físicas, sensoriais nas escolas de ensino básico bem como em instituições de ensino não formais. O presente artigo visa apresentar atividades de contação de histórias desenvolvida pelo por professores inseridos em um projeto de pesquisa que trata de materiais didáticos e ensino de geografia. O princípio básico foi de escolher histórias com caráter geográfico e também algumas clássicas da literatura infantil a fim de contá-las e depois divulgá-las por meio de canal do Youtube, páginas do facebook e para contação de histórias junto às crianças com utilização de bonecas de pano. Como resultado obteve-se a participação dos estudantes e professores envolvidos na atividade e o indicativo do potencial dessas ações lúdicas na promoção da sensibilização dos estudantes da educação infantil e ensino fundamental I para a questão do respeito ao outro.
O AQUECIMENTO GLOBAL E A DIVULGAÇÃO CIENTÍFICA NAS REVISTAS SUPERINTERESSANTE E QUERO SABER
Authors: Carvalho Igor Leandro Alves de , Rocha Marcelo Borges
Published: February 2021

O Aquecimento Global possui a capacidade de participar de discussões a nível local e global, tem potencial de ultrapassar fronteiras e entrar em discussão em diversos contextos, faz parte da agenda dos meios de comunicação, revelando seu potencial e sua importância nas diversas esferas. Esta pesquisa teve por objetivo investigar como o Aquecimento Global (AG) é abordado nas revistas Superinteressante e Quero Saber, observando o enfoque dado ao tema pelas revistas e inferindo sobre a capacidade de contextualização de cada uma delas. Todas as edições no período de 2012 a 2017 foram verificadas, no intuito de mapear os artigos que, de alguma maneira tratam da temática. Apoiado na Análise de Conteúdo, foi investigado qual o enfoque dados ao tema, e de que maneira o fato noticiado (texto) está inserido nas diversas possibilidades de contexto. Os resultados revelam uma abordagem diversificada por ambas as revistas. O tema recebe diversos enfoques e possibilita a discussão em diversos contextos, entre eles: político, histórico e socioeconômico. A diversidade de enfoque demonstra que o tema possui uma boa amplitude temática e um caráter interdisciplinar e transversal. Conseguir relacionar os conhecimentos científicos ao cotidiano do público não especialista também faz parte do papel social da DC.
PARANGOLÉS DE AÇÕES E CICLO DE AÇÕES COLETIVO: UMA PROPOSTA TEÓRICA PARA DISCUTIR INTERAÇÕES E APRENDIZAGEM COM O USO DE LOUSA DIGITAL
Authors: Carvalho Sérgio Freitas , Scherer Suely
Published: February 2021

Este artigo tem como objetivo apresentar e discutir uma proposta de articulação teórica para analisar movimentos de aprendizagem com uso de Lousa Digital. Trata-se de uma proposta teórica denominada de Ciclo de Ações Coletivo, que articula estudos de José Armando Valente, sobre o Ciclo de Ações ao realizar atividades usando o computador, e estudos de Jaan Valsiner, sobre a Psicologia Cultural, em especial a aprendizagem compreendida a partir de processos de internalização e externalização de mensagens. A obra Parangolé, do artista plástico Hélio Oiticica, oportunizou o encontro com a representação de uma das ações vivenciadas na construção teórica proposta, os movimentos denominados Parangolés de Ações. Essa construção teórica, o Ciclo de Ações Coletivo (- Parangolé de Ações -  Descrição - Execução -) pode orientar ações com uso da Lousa Digital em sala de aula de diferentes disciplinas.
IN VITRO METABOLISM OF COPALIC AND KAURENOIC ACIDS IN RAT AND HUMAN LIVER MICROSOMES
Authors: Mauro Mariana , Silva Rodrigo , Campos Michel , Bauermeister Anelize , Lopes Norberto , Moraes Natalia
Published: February 2021

Copalic (CA) and kaurenoic (KA) acids are the main diterpenes found in the oleoresin extracted from the copaiba tree (Copaifera sp). This study aimed to characterize the metabolism of CA and KA in rat and human liver microsomes using liquid chromatography with tandem mass spectrometry (LC-MS/MS). The in vitro assays showed deviations from the Michaelian kinetics in the metabolism of CA and KA. Putative metabolites of CA and KA were characterized by LC-MS/MS using electrospray ionization (ESI) with time of flight (LC-ESI-TOF) and ion-trap (LC-ESI-IT) systems and identified as a CA isomer and 16,17-dihydroxy-kaurenoic acid, respectively. CA and KA are subject to extensive metabolism with each passage through the liver with extraction ratios (E) estimated as 0.97 and 0.99, respectively. In conclusion, the kinetic parameters and metabolites described here might support drug development and the traditional use.
ISO/IEC 17025: HISTORY AND INTRODUCTION OF CONCEPTS
Authors: Miguel Anna , Moreira Renata , Oliveira André
Published: February 2021

Quality is an increasingly present concept nowadays, so meeting the customers’ needs, who buy and use products and hire services, becomes essential. For laboratories, the concept is applied to the reliability and traceability of the results produced and presents itself not only to meet the customer’s needs, but also to allow the signing of agreements in the international trade. The concept of Quality in a laboratory can be carried out from the elaboration of a Quality Management System (QMS). To this end, the normative document ISO/IEC 17025, internationally accepted, has been changing over the years aimed at instructing the elaboration of a management system which proves the technical capacity of testing and calibration laboratories and guides the generation of reliable results. The document is in its third version as a standard, the most current one published in 2017, and it presents requirements to achieve the proposed objective and the quality assurance. In the face of the importance of these concepts and the unquestionable need of laboratories to provide reliable and traceable results, this article presents the norm history and its most recent changes. Its intent is support laboratories whose objective is to implement a QMS according to this normative reference
UMA PROPOSTA DE ANÁLISE DAS QUESTÕES DE QUÍMICA NO ENADE EM FUNÇÃO DO NÍVEL COGNITIVO DE DIFICULDADE
Authors: Silva Márcia , Mazzé Fernanda , Silva Jonathan , Souza Dayana , Medeiros Maria
Published: February 2021

A PROPOSAL FOR ANALYZING CHEMISTRY ISSUES AT ENADE ACCORDING TO THE COGNITIVE LEVEL OF DIFFICULTY. This article aims to present an analysis of the ENADE-Chemistry exam using a taxonomy based on the cognitive operations mobilized to solve the chemistry issues here called as Cognitive Level of Difficulty. In addition to identifying contents in the area of knowledge, skills and competences. All questions from the exams of the years 2011, 2014 and 2017 were analyzed; selected the statistical data present on the reports issued by INEP for four higher-educational institutions (UFRN, UTFPR, UFU and UFAM) and the percentages of the distractors indicated. These data were organized in an excel spreadsheet (database) that helped the comparisons of different variables. As a result, we observed discrepancies when comparing the variables of the ease index and the cognitive level of difficulty for the questions that addressed general chemistry concepts. For example, issues considered very difficult in the easiness rating, but which required low order thinking skills and reciprocally. We consider the proposed taxonomy of analysis of cognitive operations and the database is a tool that can contribute to their courses structure. Furthermore, the proposal can be extended to other areas.
Death of the saint Clement. The new evidence concerning tradition about Saint’s
Authors: GAWROŃSKI RADOSŁAW ANDRZEJ , KARASIEWICZ-SZCZYPIORSK RADOSŁAW I
Published: February 2021

Zgodnie z późnoantyczną tradycją cesarz Trajan zesłał papieża Klemensa na Krym, aby pracował w kamieniołomie położonym w pobliżu Chersonezu Taurydzkiego. Według legendy Papież poniósł męczeńską śmierć w miejscu wygnania, wrzucony do morza z kotwicą u szyi. Wiarygodność tego świadectwa była często kwestionowana. Autorzy niniejszego artykułu starają się argumentować, że niektóre elementy wyżej wspomnianej tradycji mogły zawierać rdzeń prawdy. Badania zabytków kamiennych znalezionych w rzymskiej świątyni położonej nieopodal fortu w Bałakławie-Kadykowce i próbek z fortyfikacji Chersonezu Taurydzkiego wskazują, że w Inkermanie pod nadzorem rzymskiej armii pracował kamieniołom wapienia. Niestety, najwcześniejszą działalność tego typu można datować dopiero na czasy Antoninusa Piusa. Jednak analiza próbek kamienia uzyskanych z fortyfikacji Chersonezu Taurydzkiego sugeruje, że za panowania Trajana w pobliżu murów miejskich pod nadzorem armii rzymskiej działał inny kamieniołom. Wydaje się, że miejscowa tradycja dotycząca obecności rzymskiego kamieniołomu w Inkermanie została później wymieszana z wcześniejszymi legendami o męczeństwie papieża Klemensa.
Klasztory kapucynów w strukturze urbanistycznej barokowych miast Śląska
Authors: Ludwig Bogna
Published: February 2021

Po wojnie trzydziestoletniej w miastach śląskich rosnące znaczenie miały zespoły klasztorne. Przebudowywano te przynależne do dawnych zgromadzeń i wznoszono utworzonych w czasach nowożytnych. Wyróżniały się przede wszystkim budynki jezuitów. W zupełnie inny sposób odznaczały się klasztory kapucynów. Tylko dwa z nich zachowały się do dziś, o pozostałych można jednak zebrać podstawowe informacje. Uwidacznia się konsekwentny sposób zakładania konwentów i charakterystyczne cechy stosowanej architektury – powtarzalnych układów o silnie ujednoliconych wymiarach i formach. Manifestacyjna skromność, wyrażana przez schematyczną fasadę kościoła była przekazem duchowości i zasad działania kapucynów.
In das Palais am Ballplatze zieht ein neuer Herr ein – reakcje prasy na nominację Agenora Gołuchowskiego młodszego
Authors: Strzelczyk Agata
Published: February 2021

Niniejszy artykuł dotyczy oddźwięku, jaki w prasie wywołała nominacja na stanowisko ministra spraw zagranicznych Austro-Węgier Agenora Gołuchowskiego młodszego. Nominacja ta komentowana była zarówno w prasie monarchii habsburskiej i nie tylko w polskojęzycznej prasie trzech zaborów, ale również w gazetach wychodzących w innych państwach, aż do odległych wysp Nowej Zelandii. W artykule zostaje dokonany przegląd wypowiedzi prasowych, a także porównanie zamieszczanych opinii i doboru faktów. Materiał źródłowy, chociaż jednakowej natury, jest różnorodny - od obszernych analiz politycznych, zamieszczonych w prasie wiedeńskiej, aż po lakoniczne wzmianki w gazetach nowojorskich czy nowozelandzkich.
Kult siedmiu archaniołów w średniowiecznej Nubii na tle kultu siedmiu planetarnych bogów w basenie Morza Śródziemnego
Authors: Łaptaś Magdalena
Published: February 2021

Prace polskich archeologów w Sudanie, trwające od tzw. „Kampanii Nubijskiej” (1961-1964), stale wzbogacają wiedzę o chrześcijańskiej Nubii. Nowe badania nie tylko zmuszają do korygowania wiedzy na temat Nubii, ale także do świeżego spojrzenia na średniowieczne chrześcijaństwo. Ciekawym wątkiem nubijskiej angelologii są świadectwa kultu siedmiu archaniołów potwierdzone w inskrypcjach, a także w malarstwie i architekturze. W przypadku Nubii nie zachowały się obszerne opisy rozwoju kultu archaniołów i wiedza opiera się na łączeniu pojedynczych informacji, które po zebraniu tworzą pełny obraz. Celem niniejszego artykułu jest zebranie tych informacji i pokazanie, iż kult archaniołów rozwijał się w Nubii i istniał pewien stały skład imion tych archaniołów.
Dialog międzyreligijny w sztuce wczesnopiastowskiej
Authors: Urbańczyk Przemysław
Published: February 2021

Nie ma źródeł historycznych ani świadectw archeologicznych czy numizmatycznych lub przedstawień artystycznych, które potwierdzałyby tradycyjną wizję szerokiej i skutecznej chrystianizacji całego kraju wkrótce po konwersji Mieszka I. Zatem, podobnie do współczesnego państewka zachodniosłowiańskich Obodrytów i do jedenastowiecznej Szwecji, chrześcijańska dynastia Piastów rządziła państwem zamieszkanym w przeważającej części przez pogan. Wydaje się, że pewne odzwierciedlenie konfrontacji ideologicznej jest dostrzegalne w symbolice artystycznej, w której można wskazać przykłady swoistego synkretyzmu, kiedy stare i nowe elementy konkurowały ze sobą i wchodziły w specyficzny dialog. Wykorzystywane w tym symbole nabierały nowych znaczeń czy choćby dwuznaczności. Znaleziska z ziem polskich mogą stanowić dobry przyczynek do takich rozważań.
Z dziejów budowy dawnego opactwa cysterskiego w Lądzie - najnowsze badania architektoniczne elewacji wschodniej klauzury
Authors: Łużyniecka Ewa
Published: February 2021

W artykule przedstawiono hipotezę przeobrażeń elewacji wschodniej klauzury opactwa cysterskiego w Lądzie. Opracowano ją na podstawie badań architektonicznych prowadzonych w 2019 roku przez zespół przy Wydziale Architektury Politechniki Wrocławskiej kierowany przez autorkę.
Wydzielono cztery zasadnicze fazy przekształceń elewacji. We wczesnym gotyku zbudowano dwukondygnacyjną ścianę, później ją podwyższono i dobudowano przedłużenie zakrystii. Kolejna faza gotycka to rozbudowa elewacji w kierunku południowym, a barokowa – podwyższenie i zmiana wystroju. Artykuł zakończono stwierdzeniem, że wiele zagadnień związanych zwłaszcza z datowaniem omawianej elewacji wymaga dalszych prac badawczych.
Stanisława ze Skarbimierza rozważania o chwale i łasce Bożej w świetle wybranych kazań Super Gloria in Excelsis
Authors: Wojciechowska Beata
Published: February 2021

Kazania z cyklu Super Gloria in excelsis, autorstwa Stanisława ze Skarbimierza (ok.1360-1431), wybitnego teologa, doktora praw, rektora odnowionego w 1400 r. Uniwersytetu Krakowskiego, poruszają niezwykle ważne kwestie teologiczne. W swoich rozważaniach Stanisław ze Skarbimierza ukazał łaskę jako dar, dla którego warto wszystko utracić, który wymaga nie tylko zachowywania przykazań Bożych, ale przede wszystkim stanowi punkt wyjścia do wielbienia Stwórcy, oddawania Mu czci i chwały. Te fundamentalne kwestie wybitny kaznodzieja zaprezentował z jednej strony w optyce refleksji teologicznej, a z drugiej przedstawił je wspólnocie wiernych tak, by stały się one ważnym i zrozumiałym elementem ich życia religijnego.
Health Insurance Status of Pregnant Women and the Likelihood of Receipt of Antenatal Screening for HIV in Sub-Saharan Africa
Authors: Hussein Muhammad Ragaa , Dongarwar Deepa , Yusuf Rafeek A. , Yusuf Zenab , Aliyu Gambo Gumel , Elmessan George Ryan , Salihu Hamisu M.
Published: February 2021

Background:

We investigated if initiating preventive care against HIV vertical transmission
by antenatal HIV screening is independent of the patients’ source of financial reimbursement
for the care received in sub-Saharan Africa (SSA).

Methods:

Using information from the WHO’s Global Health Expenditure Database and the Demographic
Health Surveys Database for 27 sub-Saharan countries, we used Spearman’s correlation
and adjusted survey logistic regression to determine the potential relationship between enrollment
in health insurance and the likelihood that expectant mothers would be offered antenatal HIV
screening.

Results:

We found that expectant mothers covered by health insurance were more than twice as
likely to be offered antenatal screening for HIV compared to the uninsured. The likelihood differed
by the type of insurance plan the expectant mother carried.

Discussion:

Health insurance is more of a financial tool that this study finds to be necessary to
boost the uptake of preventive and therapeutic HIV care in SSA.

Conclusion:

The ensuing disparity in receiving proper care could hinder the goals of 90-90-90 and
the forthcoming 95-95-95 plan in SSA.
Intracerebral Hemorrhage and Diabetes Mellitus: Blood-Brain Barrier Disruption, Pathophysiology and Cognitive Impairments
Authors: Bahadar Ghaith A. , Shah Zahoor A.
Published: February 2021

There is a surge in diabetes incidence, with an estimated 463 million individuals been diagnosed worldwide. Diabetes Mellitus (DM) is a major stroke-related comorbid condition that increases the susceptibility of disabling post-stroke outcomes. Although less common, intracerebral hemorrhage (ICH) is the most dramatic subtype of stroke associated with higher mortality, particularly in the DM population. Previous studies have focused mainly on the impact of DM on ischemic stroke. Few studies have focused on the impact of DM on ICH and discussed the blood- -brain barrier disruption, brain edema, and hematoma formation. However, more recently, investigating the role of oxidative damage and Reactive Oxygen Species (ROS) production in preclinical studies involving DM-ICH animal models has gained attention. But, little is known about the correlation between neuroinflammatory processes, glial cells activation, and peripheral immune cell invasion with DM-ICH injury. DM and ICH patients experience impaired abilities in multiple cognitive domains by relatively comparable mechanisms, which could get exacerbated in the setting of comorbidities. In this review, we discuss both the pathology of DM as a comorbid condition for ICH and the potential molecular therapeutic targets for the clinical management of the ICH and its recovery.
Synthesis of 4-Aryldihydrocoumarins via a Sequential Michael Addition- Lactonization Route
Authors: Sinha Anshu K. , Srivastava Chandra M. , Rao Gyandshwar K. , Karnatak Manvika , Verma Ved P. , Rawat Varun
Published: February 2021

Background:

Coumarin and its derivatives have attracted the attention of synthetic
chemists due to their importance in pharmaceutical and medicinal chemistry. The acid-catalyzed cyclization
route constitutes the method of choice to access these important compounds.

Objective:

In this paper, we have discussed the synthesis of 4-aryldihydrocoumarins via a one-pot
p-sulfonic acid calix[4]arene catalyzed reaction.

Methods:

The easily prepared calix[4]arene derivative catalyzes a sequential reaction involving
Michael addition followed by intramolecular lactonization to afford the title compound in effective
yield.

Results:

The described methodology is devoid of any metal salt, thus making it a very appealing
protocol to safely produce dihydrocoumarins of pharmacological importance.

Conclusion:

The easy recovery, non-toxicity, and reusability of the catalytic system are some of
the other advantages of our procedure. In addition, the catalyst efficiency is not compromised after
its successive use in reactions.
Paisagem Cultural de Transumância: A Rota da Serra da Estrela para as Campinas de Idanha
Authors: Carvalho Raquel , Marques Teresa Portela
Published: February 2021

: The transhumance cultural landscape reflects a deep knowledge of the territory. Based on pastoral activity, involves spatial, periodic and seasonal movements of livestock between mountain pastures, valleys and lowlands, to provide food. We highlight an important Portuguese route: Serra da Estrela – Idanha-a-Nova, where wool production was the main activity’s driving force. The acti‑ vity reached its peak in the Middle Ages and survived until the 1950s in Beira Interior region. Aware that change is an inherent dynamic in landscape, we cannot, however, disregard that over generations, the use of endogenous natural resources, shows an understanding of the ecosystem, contributing to the region’s cultural and landscape identity heritage.
Património Mundial e os sítios culturais em risco iminente. Primeiras reflexões
Authors: Costa Inês de Carvalho
Published: February 2021

Considering the rising impact of heritage matters in the international community and assuming the growth of worldwide recognized sites, it is relevant to reflect about their hierarchies and effectiveness of protection. Therefore, starting from the analysis of UNESCO’s List of World Heri‑ tage in Danger (2018-2019), it is proposed to clarify the degree of preservation, recognition and communication of these sites through the study of UNESCO’s webpage and some fundamental texts for the issue. Ultimately, cultural sites in imminent danger will be addressed, through the analyses of main threats and their consequences for the safeguarding and preservation of the properties
Ficção e fruição de paisagens de Oitocentos: entre o Porto e Vila Real, por Edward Quillinan
Authors: Abreu Carmen Matos
Published: February 2021

The Edward Quillinan’s novel The Sisters of the Douro highlights a set of Heritage Lands‑ capes confined by the banks of the Douro river, as well as all the anthropic process about customs and manners of the Douro inhabitants during the 2nd French invasion of northern Portugal. On the narrative stage between Porto and Vila Real, the text is deeply enriched by heritages of urban or country landscapes observed along the way, describing building and topographic details, includ‑ ing flora and fauna. Imposed by the romantic literary aesthetics, the reader also notices about a loving plot of two Portuguese young women from the Douro and two English officers, pages where deep and original cultural and anthropic perspectives are developed. This novel is generally consi‑ dered a historic document of the Portuguese Patrimony of the nineteenth century. For this reason, and in accordance with the cultural and geographical framework provided by literary realism, it is acceptable that all those heritage values can be prospectively collected and considered
Uma Casa Portuguesa: as crianças austríacas em Portugal no pós-guerra (1947-1958)
Authors: Pinho Ana R. da Silva
Published: February 2021

Between 1947 and 1958, thousands of Austrian children were hosted by Portuguese fami‑ lies and institutions as part of an action promoted by Caritas. Thus escaping, for some time, the misery of a country devastated by war, these “Caritas children” found in Portugal, under Antonio de Oliveira Salazar’s Estado Novo, shelter and, in most cases, affection: an experience that, besides having repercussions in their memories and journeys, also left marks that, although less visible, conti‑ nue to make themselves felt in Portugal. In this article we present a general outline of the research «The “Caritas Children”, between Austria and Portugal (1947-1958)», which was aimed to understand the way the Action took place, its repercussions on those involved, the way it was dealt with by government agencies and displayed by the press at its service and perceived by the population.
Developing the educational guidelines and model core curriculum for speech-language-hearing therapists in Japan
Authors: Uchiyama Chizuko
Published: February 2021

Children with autism and language developmental delays have unique needs when it comes to language learning. Speech-language-hearing therapists (SLHTs) are qualified to fulfil these needs, as one of the areas of their expertise, providing necessary treatment and support. Unfortunately,
however, the existing number of SLHTs is not sufficient to meet the growing demand for these types of professionals in Japan. A reason for this is likely to be the low pass rate for qualifying therapists. As such, if researchers can find a way to increase this pass rate, the number of qualified
SLHTs would increase and demand would be met. This is the goal of Professor Chizuko Uchiyama and her team based at the Department of Speech, Language and Hearing Therapy, Mejiro University, Japan, and Japanese Association of Speech-Language-Hearing Therapists. Chizuko, who is herself a trained
SLHT, created a model core curriculum (MCC) that was completed in 2018 and complies with specific training rules and guidelines for SLHTs and also takes into account the educational content that is anticipated to be needed in the future. The goals of this work are to improve the training education
provided to SLHTs, thereby increasing the national examination pass-rate for qualified therapists of this kind and producing high-quality SLHTs. This will ultimately ensure there is an adequate number of qualified SLHTs to fulfill growing demand and lead to a higher standard of education and
care for children with autism and language development delays. The larger impact of this will be enhanced societal welfare and benefits for people with communication and hearing problems.
Study on the effect of providing learning opportunities on the formation of intention to continue work for non-regular professionals
Authors: Maeda Takao
Published: February 2021

In Japan, almost 40 per cent of employees are so-called 'non-regular employees'. That is to say, employees with a limited duration of employment. This is in opposition to their 'regular employee' counterparts who are full-time workers without a limited duration of employment. Non-regular
employees include both part-time and full-time workers with a short- or intermediate-term of employment. The percentage of non-regular employees is on the rise in Japan and this is bringing with it decreased morale and productivity due to factors such as lack of job security. In addition,
motivation is negatively affected by non-regular employees receiving fewer opportunities, such as training, for example, than regular employees. Naturally, a lack of training and education opportunities would have an adverse effect on motivation and morale. Professor Takao Maeda is based in
the Faculty of Business, Marketing and Distribution, Nakamura Gakuen University in Japan, and is working alongside collaborators Professors Tomofumi Tohara and Shigeaki Mishima, who are both based in the Faculty of Business Administration, Osaka University of Economics in Japan. The team is
focused on research that looks at how closing disparities between regular and non-regular employment could increase the motivation of non-regular employees.
Construction of a database for the correct and incorrect use of considerate expressions, for the formation of a Japanese considerate expression dictionary
Authors: Yamaoka Masaki
Published: February 2021

Professor Masaki Yamaoka, based at the Department of Humanities, Faculty of Letters, Soka University in Japan is leading a highly collaborative and multidisciplinary team that features researchers from academic institutions around the world, with a view to clarifying the actual situation
of considerate expressions. It is hoped that this will make real contributions to anthropological fields that provide a more complete picture of what it means to be human.
 Some considerate expressions are common to all languages, while others are unique to a specific language. One
that is common to many languages is the use of 'maybe' and 'may' which have the effect of making what is said less forceful or certain. By being less emphatic, it is thought that a consideration for the other person's feelings is sometimes part of the language process. It is a usage called
'hedge' in linguistics. For example, in English, 'it might be better to' is a kind of hedge. We can use this phrase as a considerate expression like that 'it might be better to leave here' instead of 'Leave here.'
 It is worth bearing in mind that, until now, research into considerate
expressions has almost exclusively been conducted with researchers rather than the general public. Laboratory conditions can have the effect of providing an incomplete picture, so Yamaoka wants to make the research more reliable by collecting data on the actual usage of considerate expressions
by members of the general public. A large-scale corpus of written and spoken language has already been developed in Japanese, Professor Yamaoka in the process of collecting as many examples of considerate expressions as possible and storing them in the database. The Japanese considerate expression
dictionary can be composed by selecting information which is beneficial to Japanese learners from the database. In addition, Professor Yamaoka would also like to publish this database among researchers for the convenience of those who are engaged in research on considerate expressions in the
future.
Shining a light on the cloud
Authors: Annette Lucy
Published: February 2021

The Social Sciences & Humanities Open Cloud (SSHOC) is a 40-month-long project under the umbrella of the European Open Science Cloud (EOSC) and funded by Horizon 2020. This project unites 20 partner organisations as well as their 27 associates. SSHOC seeks to create interconnected
data infrastructures focused on an integrated, cloud-based network structure.
Синтез и исследование структуры и свойств фотоактивных ZnO-SnO_2-Ag(AgCl) наноматериалов для медицины и экологических приложений
Authors: Волынкин В.М. , Данилович Д.П. , Евстропьев С.К. , Дукельский К.В. , Сенчик К.Ю. , Садовничий Р.В. , Киселев В.М. , Багров И.В. , Саратовский А.С. , Никоноров Н.В. , Безбородкин П.В.
Published: February 2021

Photoactive ZnO-SnO2-Ag(AgCl) nanomaterials have been prepared by polymer-salt method. Prepared materials able to generate singlet oxygen under UV and blue light irradiation. Materials structure and properties have been studied by optical and luminescence spectroscopy, XRD and SEM analysis. It was found that the structure of ZnO-SnO2-Ag(AgCl) materials consists of hexagonal ZnO, tetragonal SnO2, Ag and AgCl crystals having size 50÷60 nm. Obtained materials able to generate chemically active singlet oxygen under UV irradiation and have high bactericidal properties against both gram-positive and gram-negative bacteria. The increase of Ag content enhances the bactericidal properties of prepared materials.
Ecological Momentary Assessment Using Smartphones in Patients With Depression: Feasibility Study
Authors: Maatoug Redwan , Peiffer-Smadja Nathan , Delval Guillaume , Brochu Térence , Pitrat Benjamin , Millet Bruno
Published: February 2021

Background

Ecological momentary assessment (EMA) is a promising tool in the management of psychiatric disorders and particularly depression. It allows for a real-time evaluation of symptoms and an earlier detection of relapse or treatment efficacy. The generalization of the smartphone in the modern world offers a new, large-scale support for EMA.

Objective

The main objective of this study was twofold: (1) to assess patients’ compliance with an EMA smartphone app defined by the number of EMAs completed, and (2) to estimate the external validity of the EMA using a correlation between self-esteem/guilt/mood variables and Hamilton Depression Rating Scale (HDRS) score.

Methods

Eleven patients at the Pitié-Salpêtrière Hospital, Paris, France, were monitored for 28 days by means of a smartphone app. Every patient enrolled in the study had two types of assessment: (1) three outpatient consultations with a psychiatrist at three different time points (days 1, 15, and 28), and (2) real-time data collection using an EMA smartphone app with a single, fixed notification per day at 3 pm for 28 days. The results of the real-time data collected were reviewed during the three outpatient consultations by a psychiatrist using a dashboard that aggregated all of the patients’ data into a user-friendly format.

Results

Of the 11 patients in the study, 6 patients attended the 3 outpatient consultations with the psychiatrist and completed the HDRS at each consultation. We found a positive correlation between the HDRS score and the variables of self-esteem, guilt, and mood (Spearman correlation coefficient 0.57). Seven patients completed the daily EMAs for 28 days or longer, with an average response rate to the EMAs of 62.5% (175/280). Furthermore, we observed a positive correlation between the number of responses to EMAs and the duration of follow-up (Spearman correlation coefficient 0.63).

Conclusions

This preliminary study with a prolonged follow-up demonstrates significant patient compliance with the smartphone app. In addition, the self-assessments performed by patients seemed faithful to the standardized measurements performed by the psychiatrist. The results also suggest that for some patients it is more convenient to use the smartphone app than to attend outpatient consultations.
Supervised Exercise Therapy Using Mobile Health Technology in Patients With Peripheral Arterial Disease: Pilot Randomized Controlled Trial
Authors: Paldán Katrin , Steinmetz Martin , Simanovski Jan , Rammos Christos , Ullrich Greta , Jánosi Rolf Alexander , Moebus Susanne , Rassaf Tienush , Lortz Julia
Published: February 2021

Background

Mobile health interventions are intended to support complex health care needs in chronic diseases digitally, but they are mainly targeted at general health improvement and neglect disease-specific requirements. Therefore, we designed TrackPAD, a smartphone app to support supervised exercise training in patients with peripheral arterial disease.

Objective

This pilot study aimed to evaluate changes in the 6-minute walking distance (meters) as a primary outcome measure. The secondary outcome measures included changes in physical activity and assessing the patients’ peripheral arterial disease–related quality of life.

Methods

This was a pilot two-arm, single-blinded, randomized controlled trial. Patients with symptomatic PAD (Fontaine stage IIa/b) and access to smartphones were eligible. Eligible participants were randomly assigned to the study, with the control group stratified by the distance covered in the 6-minute walking test using the TENALEA software. Participants randomized to the intervention group received usual care and the mobile intervention (TrackPAD) for the follow-up period of 3 months, whereas participants randomized to the control group received routine care only. TrackPAD records the frequency and duration of training sessions and pain levels using manual user input. Clinical outcome data were collected at the baseline and after 3 months via validated tools (the 6-minute walk test and self-reported quality of life). The usability and quality of the app were determined using the Mobile Application Rating Scale user version.

Results

The intervention group (n=19) increased their mean 6-minute walking distance (83 meters, SD 72.2), while the control group (n=20) decreased their mean distance after 3 months of follow-up (–38.8 meters, SD 53.7; P=.01). The peripheral arterial disease–related quality of life increased significantly in terms of “symptom perception” and “limitations in physical functioning.” Users’ feedback showed increased motivation and a changed attitude toward performing supervised exercise training.

Conclusions

Besides the rating providing a valuable support tool for the user group, the mobile intervention TrackPAD was linked to a change in prognosis-relevant outcome measures combined with enhanced coping with the disease. The influence of mobile interventions on long-term prognosis must be evaluated in the future.

Trial Registration

ClinicalTrials.gov NCT04947228; https://clinicaltrials.gov/ct2/show/NCT04947228
REFLECTIVE LEARNING IN CHILDBIRTH CARE TO IMPROVE SELF-CONFIDENCE OF MIDWIFERY STUDENTS
Authors: Fadilah Lola Noviani , Husin Farid , Nurihsan Juntika , Ramdani Tria Giri
Published: February 2021

Background: Childbirth care is the core competency of a midwife which is found in midwifery education. Midwifery students must be equipped with the competencies. Self-confidence is an internal factor affecting the professional knowledge and competence of midwives. Low self-confidence shows in the practice of childbirth care thus the condition can be an indicator of the performance of a less-competent midwife in the future. Practice learning methods that support increased confidence should direct students to self-study based on experience so that it can solve the problem. Knowing the advantage of this method, it is valuable if reflective learning is implemented to improve self-confidence. The study aimed to analyse the influence of reflective learning on childbirth care practice for the improvement of student confidence.Methods: This research employed a quasi-experimental control group design, involving all midwifery students of semester IV at midwifery department that divided into treatment and control groups. The treatment is the implementation of reflective learning in laboratory and clinical practice. The confidence score was obtained by using questionnaires before and after treatment. Analysis of the characteristic data and pre-test with normal distribution using an unpaired T test. While the post-test  and percent increased score were not distributed normally, therefore Mann-Whitney U was tested.Results: It was revealed that there was no difference in the characteristics of respondents and pre-tests (p > 0.05). There were significant differences in post-test and percent increase (P < 0.05). Conclusion: Reflective learning can improve students’ confidence in childbirth care. Keywords: reflective learning, confidence, childbirth care.
UM PESSIMISTA CONVICTO NA MINHA EQUIPE: ESTILOS DE LIDERANÇA E MOTIVAÇÃO
Authors: Lucatelli Francine , Tormen-Ferreira João Anselmo , Alberton Anete , Marinho Sidnei Vieira
Published: February 2021

O caso foi desenvolvido para estimular a discussão sobre estilos de liderança e motivação, buscando soluções possíveis para minimizar ou solucionar o dilema que envolve a gestão de pessoas. Por meio da experiência vivida por Jéssica, uma jovem líder que possui em sua equipe Luís, um colaborador com anos de empresa e um comportamento que a coloca em situações difíceis diante de sua equipe, espera-se que os estudantes proponham alternativas para a situação apresentada ancoradas nas teorias de liderança e motivação. Recomenda-se a aplicação deste caso em cursos de ensino superior em nível de graduação, tecnólogo ou técnico, como os cursos de Administração, Recursos Humanos e Processos Gerenciais. Pode, ainda, ser aplicado em cursos de extensão ou treinamentos de lideranças.
Canadian dairy regulations as a driver of foreign direct investment: the case of Saputo
Authors: Rude James , Goddard Ellen
Published: February 2021

Across North America dairy processors are facing financial difficulties, yet a Canadian processor continues to grow through acquisitions of its competitors. This company, Saputo, grew up in a highly regulated marketplace where input raw milk supplies are restricted, input prices are inflated and imports of final product are restricted. This study asks if the Canadian system of dairy supply management prodded and assisted Saputo into making acquisitions at home and abroad. An empirical model estimates the probability of Saputo making acquisitions as a function of factors influenced by supply management and control variables accounting for Saputo’s financial performance. The results indicate that cash flows, which may be increased by regulatory rents, and a measure of restrictiveness of the Canadian milk supply, both are statistically significant positive determinants of the probability that Saputo will make an acquisition. On average over the estimation period removing the Canadian supply managed regime would reduce the probability of acquisitions by 7%. The implication is that the Canadian system is losing investment and employment opportunities by retaining its restrictive regulatory system.
Co-infection by Cryptococcus neoformans fungaemia and Non tuberculous Mycobacterium together with Pneumocystis jiroveci pneumonia in a patient with newly diagnosed HIV infection
Authors: Subahi Eihab , aljafar safwan , barjas haidar , Abdelrazek Mohamed , Rasoul Fatima
Published: February 2021

Opportunistic infections are common in human immunodeficiency virus
(HIV)-infected patients. Co-infections with Cryptococcus neoformans
together with Mycobacterium and Pneumocystis jiroveci pneumonia (PCP)
are rare, and typically occur in immunocompromised individuals,
particularly AIDS patients.