bluuebunny/crossref_metadata_2025 huggingface dataset:
REPRESENTACIONES SOCIALES DEL ALCOHOLISMO: EXPERIENCIAS DE UN GRUPO DE USUARIOS ABSTINENTES
Authors: Silva Sílvio Éder Dias da , Rodrigues Diana Madeira , Oliveira Márcia Aparecida Ferreira de , Araújo Jeferson Santos , Rodrigues Diego Pereira , Santos Arielle Lima dos , Costa Thiago dos Reis de Oliveira
Published: December 2024

RESUMEN OBJETIVO: comprender las representaciones sociales del alcoholismo entre alcohólicos abstinentes de un grupo terapéutico y sus repercusiones en la atención en el Centro de Atención Psicosocial de Alcohol y Otras Drogas. Método: estudio cualitativo con la participación de 20 entrevistados, utilizando la técnica de asociación libre de palabras; estudio realizado en el CAPS-AD III de la ciudad de Belém - Pará - Brasil, en 2023. Datos analizados mediante análisis temático seguido de seis etapas. Resultados: la trayectoria de consumo problemático de alcohol fue revelada a través de sus representaciones sociales, en las que construyeron formas de cuidado vinculadas principalmente al sentido común. Se puede inferir que, sufriendo de alcoholismo, buscan la dignidad y el retorno a la vida cotidiana. Consideraciones finales: el estudio muestra que el desvelamiento de las representaciones sociales favorece la acogida de la familia y de los profesionales de salud mental, por lo que el Centro de Atención Psicosocial se revela como una nueva oportunidad para los usuarios abstinentes. seguido de seis etapas.
EDUCATIONAL PODCAST ON LEPROSY AS A LEARNING RESOURCE
Authors: Ferreira Mirthis Cordeiro , Costa Raphael Henrique Gomes da , Muniz Ricardo Alexandre Amaral , Santos Carlos Renato dos , Santos Claudia Benedita dos , Vasconcelos Eliane Maria Ribeiro de
Published: December 2024

ABSTRACT Objective: Evaluate the effect of a podcast as an educational action on Youth and Adult Education (EJA) students in learning about leprosy. Method: Prospective, quasi-experimental study. An educational action was carried out with an educational podcast about leprosy in public schools in Recife, Pernambuco, 2024. The sample consisted of 211 students and the selection was non-probabilistic by convenience. The collection took place through a questionnaire involving content about leprosy, and McNemar was used to assess the significance of the changes. Results: After the intervention, there was an increase in the number of students with adequate knowledge, with the proportion of changes from errors in the pre-test to correct answers in the post-test being greater (p < 0.05) than the proportion of changes from correct answers in the pre-test to errors in the post-test for the questions. Conclusion: Using tools like podcasts in health education enables access and dissemination of information, promoting knowledge and changes in individual and collective health behavior.
CLINICAL DETERIORATION OF THE ONCOLOGY CHILD: RELIABILITY OF A NEW TOOL ADAPTED FROM THE BRIGHTON PEDIATRIC EARLY WARNING SCORE
Authors: Soares Nataly Tsumura Inocêncio , Soares Marcos Hirata , Pimenta Rosângela Aparecida
Published: December 2024

ABSTRACT Objective: To measure the degree of reliability of the construction of new items and the adaptation of the Brighton Pediatric Early Warning Score for children with cancer. Method: Methodological study to analyze the equivalence of inter-judge content regarding the inclusion of items in the scale to detect early clinical deterioration in children with cancer: signs of bleeding, changes in temperature, and presence of grade III/IV mucositis. The Intraclass Correlation Coefficient and Cronbach’s Alpha were used for analysis, considering a value ≥0.750. Results: Based on the judges’ feedback, the items proposed for inclusion were retained, with minor adjustments to the scores. Thirty nurses (86.1%) and six doctors (13.9%) from Brazil evaluated the scale, resulting in an intraclass correlation coefficient of 0.823. Conclusion: The instrument proved suitable, with theoretical relevance and practical application, for early detection of clinical deterioration in children with cancer. To this end, it contributes to timely identification by the team, minimizing unfavorable outcomes.
CLIMA E CULTURA ORGANIZACIONAL: IMPLICAÇÕES PARA A PRÁTICA DE ENFERMEIROS EXTRA-HOSPITALARES
Authors: Silva Márcio Daniel Dias de Almeida e , Magalhães José Fernando da Silva Monteiro Oliveira de , Azevedo Guilherme Eça Guimarães Gonçalves , Queirós Cristina , Borges Elisabete
Published: December 2024

RESUMO: Objetivo: Este estudo pretende identificar o clima e a cultura organizacional entre enfermeiros que trabalham em Ambulâncias de Suporte Imediato de Vida (ASIV). Métodos: Foi realizado um estudo descritivo, quantitativo e transversal com 81 enfermeiros portugueses que atuam em Ambulâncias de Suporte Imediato de Vida no Instituto Nacional de Emergência Médica (INEM). Os dados foram analisados pelo método de análise de componentes principais (ACP), seguido de uma rotação Varimax, e os modelos foram validados mediante os testes Kaiser-Meyer-Olkin e de esfericidade de Bartlett. Resultados: A análise fatorial produziu quatro fatores, a saber: Suporte (24,5%), Objetivos (13,6%), Regras (9,7%) e Inovação (8,01%), associados ao clima e à cultura organizacional. Enfermeiros com um diploma de graduação perceberam significativamente mais suporte do que aqueles com qualificações mais altas. O suporte também variou de acordo com o estado civil, revelando que enfermeiros casados tiveram uma percepção maior do que aqueles que coabitavam. Conclusão: O clima e a cultura organizacional contribuem de forma inequívoca para o desenvolvimento de um ambiente de trabalho saudável e seguro e são decisivos para a qualidade da assistência de enfermagem.
CLIMA Y CULTURA ORGANIZACIONAL: IMPLICANCIAS PARA LA PRÁCTICA DE LOS ENFERMEROS EXTRAHOSPITALARIOS
Authors: Silva Márcio Daniel Dias de Almeida e , Magalhães José Fernando da Silva Monteiro Oliveira de , Azevedo Guilherme Eça Guimarães Gonçalves , Queirós Cristina , Borges Elisabete
Published: December 2024

RESUMEN Objetivo: Este estudio tiene como objetivo identificar el clima y la cultura organizacional de los enfermeros que trabajan en Ambulancias de Soporte Vital Inmediato (ASVI). Métodos: Se realizó un estudio descriptivo, cuantitativo y transversal con 81 enfermeros portugueses que trabajan en Ambulancias de Soporte Vital Inmediato del Instituto Nacional de Emergencias Médicas (INEM). Los datos se analizaron mediante el método de análisis de componentes principales (ACP), seguido de rotación Varimax, y los modelos se validaron mediante las pruebas de esfericidad de Kaiser-Meyer-Olkin y Bartlett. Resultados: El análisis factorial arrojó cuatro factores, a saber: Apoyo (24,5%), Objetivos (13,6%), Reglas (9,7%) e Innovación (8,01%), asociados al clima y la cultura organizacional. Los enfermeros con un título de grado notaron que recibían bastante más apoyo que quienes tenían calificaciones más altas. El apoyo también varió según el estado civil, dado que los enfermeros casados tenían una percepción mayor del mismo que los que estaban en unión de hecho. Conclusión: El clima y la cultura organizacional contribuyen inequívocamente al desarrollo de un ambiente de trabajo saludable y seguro y son decisivos para la calidad de la atención de enfermería.
Covid-19 e tempos de crise: entre o risco e o cuidado
Authors: Lerner Kátia , Aisengart Rachel
Published: December 2024

Resumo Este artigo reflete sobre as noções de risco e cuidado em contextos de crise, tendo em vista a experiência social da covid-19. Trata-se de compreender como as instituições e os sujeitos que protagonizaram o debate público lidaram com a noção de perigo. O foco do artigo incide sobre os seguintes eixos de reflexão: o discurso midiático, os pronunciamentos do então presidente Bolsonaro, o posicionamento de profissionais de saúde e a perspectiva de sujeitos no cotidiano dos cuidados e do adoecimento. A análise de material jornalístico, pronunciamentos de autoridades governamentais e trabalhos científicos sobre os dois primeiros anos da pandemia revelou a polissemia dessas concepções. Observa-se uma tensão em torno da noção de gravidade, uma vez que a pandemia tanto era vista como evento ordinário quanto excepcional; e o cuidado formulado como dimensão individual e, também, coletiva; na qual os cuidadores estavam marcados pela vulnerabilidade, angústia e exaustão. A experiência pandêmica nesse contexto se deu sob a égide do desamparo estatal e institucional, diante de condições políticas marcadas pelo recrudescimento da extrema direita e o governo Bolsonaro.
Epistylid ciliates as epibionts on calanoid copepods in an Amazonian floodplain lake (Batata Lake)
Authors: Flores Wésley Altino , Souza Pedro Mendes de , Josué Iollanda Ivanov Pereira , Dias Roberto Júnio Pedroso , Bozelli Reinaldo Luiz
Published: December 2024

Abstract Aim The main objective was to investigate changes in the prevalence and infestation intensity of the epibiotic relationship (ciliates/calanoids) in relation to the impact of bauxite tailings (natural and impacted areas) during two distinct periods of the hydrological pulse (rising and high-water). Methods The hydrological pulse of this system can be characterized with four distinct phases: rising, high-water, falling, and low-water. After degradation by bauxite tailings for ten years (1979-1989), and despite an ongoing long-term ecological restoration process, it is still possible to recognize two distinct regions in the lake: the area impacted by the tailings and the natural area. We sampled zooplankton (calanoids and epibiont ciliates) and limnological variables during the high-water period (March 2015) and rising-water period (June 2019) at twelve sampling points in Lake Batata, six in the impacted area and six in the non-impacted area. Results This is the first record of peritrichous epibiont ciliates Epistylis sp. colonizing calanoid copepods in Amazonian ecosystems (Lake Batata, Pará, Brazil). We recorded epibiont ciliates in the calanoid copepodite and adult stages, as well as the main location sites on the thorax and abdomen. Our study recorded a significant difference in the prevalence and mean infestation intensity between the natural and bauxite tailings-impacted areas, and in the prevalence of infestation between the rising -water (2015) and high-water (2019) collections. The prevalence of infestation was higher in the impacted area and during the rising-water period. Conclusions Although the host/epibiont/environment interaction is complex and requires analysis with a larger number of temporal samples, this study records a clear effect of flooding in this Amazonian system on the spatial and temporal dynamics of epibiont ciliates associated with calanoid copepods.
Biotransformation of Dehydroepiandrosterone by Penicillium olsonii MRC500780
Authors: Kuru Ali , Albayaty Mena
Published: December 2024

This work reported the biotransformation of dehydroepiandrosterone 1 with Penicillium olsonii MRC500780. Structure determinations revealed that biotransformation of 1 by Penicillium olsonii MRC500780 afforded androst-4-ene-3,17-dione 2, 15α-hydroxyandrost-4-ene-3,17-dione 3, 3β,7β-dihydroxyandrost-5-ene-17-one 4, 3β,7α-dihydroxyandrost-5-ene-17-one 5, and 15α,17β-dihydroxyandrost-4-ene-3-one 6. This fungus primarily isomerized the starting material in terms of the double bond and the hydroxyl group at 3β oxidised, then hydroxylated it at the C-15α position and reduced it at the C-17 position; also, hydroxylations at the C-7α position and C-7β position were observed.
Cultural Heritage Data for Research – An Introduction
Authors: Dressen Angela
Published: December 2024

This article is an introduction to the collected essay volume ‘Cultural Heritage Data for Research – Opening Museum Collections, Project Data and Digital Images for Research, Query and Discovery’, published in vol. 10.2, 2024 and vol. 11.1, 2025 of the Open Library of Humanities Journal (see https://olh.openlibhums.org/issue/905/info/). The introduction highlights some methods of approaching humanities data, and sheds light on current trends. In particular, it focusses on museum data as research data for Art History and Cultural Heritage Studies and describes new ways of data querying.
On the number of pursuers that guarantees the capture of the evader in the game on the graph of icosahedral edges
Authors: Azamov Abdulla A. , Азамов Абдулла Азамович , Holboyev Azamat G. , Холбоев Азамат
Published: December 2024

The article is devoted to the study of the change in the optimal number of pursuers when removing one edge in a differential game on graphs. It is shown that when one edge of the icosahedron is removed, two pursuers are sufficient to capture the evader, whereas for the icosahedron itself, this number is 3.
Study of computational complexity of the algorithm for finding the traffic flow Wardrop equilibrium
Authors: Chirkova Julia V. , Чиркова Юлия Васильевна
Published: December 2024

The paper describes an algorithm for finding the Wardrop equilibrium and optimal distribution of traffic flows in the urban road network. Implementing this algorithm, the software has been developed. To study the computational complexity of the algorithm for finding the equilibrium distribution of traffic flows depending on the model dimension, the process of conducting and analyzing the results of computational experiments is presented.
Differential pursuit games of neutral type with integral restrictions on player controls
Authors: Mamadaliyev Numanjon A. , Мамадалиев Нуманжон А. , Mustapokulovpov Hamdam Ya. , Мустапокулов Хамдам Я. , Abdumannopov Muhammadsodiq M. , Абдуманнопов Мухаммадсодик М.
Published: December 2024

In this paper, we study linear differential games described by a system of linear differential-difference equations of neutral type under integral constraints on the controls of the players. We obtain new sufficient conditions on parameters of the process guaranteeing finishing the game in a definite finite time.
Evolución del financiamiento a las pymes en Ecuador: un estudio en la provincia El Oro
Authors: Urdaneta-Montiel Armando José , Melean-Romero Rosana Alejandra , Prieto-Pulido Ronald Antonio
Published: December 2024

Objetivo: la investigación buscó examinar la evolución de la cartera de créditos de las pymes en Ecuador, abordando el estudio en la provincia El Oro con el fin de entender su impacto en el crecimiento económico y la sostenibilidad empresarial, especialmente a la luz de los recientes desafíos globales. Método: se abordó bajo el paradigma positivista con enfoque cuantitativo de tipo analítico-descriptivo y un diseño no experimental. Se aplicó una encuesta a 54 ejecutivos de crédito de las entidades bancarias de la provincia. Resultados: se identificaron diversas limitaciones que obstaculizan el acceso al crédito, como la legislación mercantil restrictiva, la falta de información financiera adecuada, la escasa facturación, las expectativas limitadas de rentabilidad en proyectos a largo plazo y las inversiones en tecnología, así como la intersección de finanzas personales y empresariales en algunos propietarios de pymes. Estas limitaciones generan distorsiones e ineficiencias en la asignación de los recursos financieros, especialmente en el capital de trabajo. Conclusiones: se evidencia que menos del 1 % de las empresas (empresas grandes) concentran el 53,04 % del crédito, mientras que el resto del parque empresarial (99%), concentra el 30,88 % de la cartera de créditos total de la provincia. Para que las pymes accedan a financiamiento, es importante que demuestren un crecimiento sostenible y la eficiencia en el uso de sus recursos, respaldado por registros financieros confiables a largo plazo.
Reimagining Agricultural Advisors and Educators as Agricultural Bricoleurs Towards Enhanced Skills Transfer: An Adult Learning Perspective
Authors: Teele T. , Nkoane M.M.
Published: December 2024

Bricolage's approach describes how post-colonial, post-positivist, post-modernist, or post-structuralist paradigms have driven intellectuals to develop mixed multi-theoretical and multi-methodological methods. Bricoleurs must contextualise the approaches using the metaphor and articulate its meaning and inferences for advisory services in attempting to do so, as agricultural advisors as bricoleurs and emerging farmers view themselves as co-advisors, guided by bricolage principles. The bricoleurs, equipped with adult education approaches and emerging farmers, will engage in a skills transfer exercise in an agricultural environment. In contrast, a bricoleur plays the role of a facilitator, not a teacher or an expert. Emerging farmers are knowledgeable, and many have years of experience working in the farming environment and have massive knowledge and experience that they can circulate amongst themselves. Bricolage highlights the relationship between agricultural advisors' ways of seeing and the social location of their personal history. The agricultural advisor-as-bricoleur abandons the quest for the naive concept of realism. It focuses instead on clariﬁcation of their position in the web of reality, the social locations of other co-advisors and the ways they shape the production and interpretation of knowledge. Bricolage tracks significant ruptures in epistemological, ontological, ethical, and political underpinnings that influence agricultural advisors. The record shows that, while traditional agricultural extension services were based on positivist rationalities, successive generations must adopt more interpretive, post-positivist, post-colonial, post-modern, constructivist, and post-structuralist approaches. As a guiding theory for agricultural extension advisors, Bricolage can improve skills transfer amongst emerging farmers by using limited resources to complete specific tasks.
Validating Small-Scale Sugarcane Farmers' Climate Perceptions Through Scientific Climate Data to Enhance Awareness of Climate Change: The Case of Swayimana Area in KZN Midlands, South Africa
Authors: Ncoyini-Manciya Z. , Manciya S.
Published: December 2024

Climate change is a serious challenge that poses an additional problem to the many existing difficulties in the agricultural sector. It will likely exacerbate an already dire situation by making current production methods less sustainable. Previous studies concluded that most people in developing countries perceive climate change as a spatially and temporally distant threat. However, recent studies have raised a new narrative, suggesting that rural communities are becoming more aware of climate change and variability. The study, therefore, aimed to compare the perceptions of climate change among small-scale sugarcane farmers with scientifically observed climate trends in the study area. The study mainly analysed rainfall and air temperature trends over twenty years and compared these with climate change, as farmers in the study area perceived. Additionally, it assessed whether the participants had implemented adaptation plans to minimise the adverse effects of the observed climate variations, both scientifically and perceptually. The study findings indicate that small-scale sugarcane farmers perceive climate change fairly accurately. Less than half of the small-scale sugarcane farmers (nearly 40%) observed increased temperatures, rainfall, drought frequency, and frost occurrence. Their perceptions aligned with the findings from the scientific data, which indicated that maximum temperature has been increasing at 0.049 oC per annum-1 from 1997 to 2017 while the rainfall showed an increase of 15.475 mm per annum-1 over the same period. These findings confirm that these farmers are becoming more aware of climate change occurring in their communities. However, the study results also show that despite the accurate perception of climate change, farmers struggle to adapt to this accurately perceived climate change. This highlights their vulnerability to climate change due to a lack of adaptive capacity. The study recommends government intervention to facilitate improved collaboration between academics and farmers for information sharing to identify possible adaptation strategies for small-scale farmers.
Reimagining Decoloniality and Extension
Authors: Mohamed Sayeed C.
Published: December 2024

The language of change in curricula is increasingly being examined through the lens of decoloniality and Africanisation. This underscores the need to consider Extension education and the practice of extension within the context of contemporary post-colonial debates. This article examined decoloniality and its relevance in the practice of Extension education. To achieve this, the article adopted an interpretative qualitative analysis of relevant literature, documents, and research findings. The findings suggest that successful decolonisation calls for Extension curricula to be attentive to content challenges, the origin and foundation of which may be deeply rooted in the ideologies and logic of the global north. Additionally, the article highlighted the necessity for academics, researchers, and practitioners to prioritise local knowledge and methodologies. This means using a variety of solutions, regardless of their origin (African or Western), and adopting the most effective approach. These measures are essential for fostering effective development within the specific context of Extension Education and developmental needs.
ESTUDO DE CASO INVESTIGATIVO: AS ESTRATÉGIAS METODOLÓGICAS UTILIZADAS POR PROFESSORES DE BIOLOGIA DE UMA ESCOLA PÚBLICA DE MACAPÁ/AP PARA PROMOVER A ALFABETIZAÇÃO CIENTÍFICA ENTRE ALUNOS COM TRANSTORNO DO ESPECTRO AUTISTA (TEA)
Authors: Fernandes Lillian Bestrize Rodrigues , Santos Paola Maria Feio , Pereira Gerlany de Fátima dos Santos
Published: December 2024

O estudo teve como objetivo compreender as estratégias metodológicas adotadas por professores de Biologia em uma escola pública estadual de Macapá-AP para ensinar alunos com Transtorno do Espectro Autista (TEA). Especificamente, buscou identificar a formação inicial e continuada dos professores, seu tempo de atuação e experiência com alunos com TEA, e como aplicam metodologias e estratégias para Alfabetização Científica (AC). Utilizou-se uma pesquisa qualitativa com estudo de caso, conforme Yin (2010), incluindo entrevistas semiestruturadas e observação participante na Escola Estadual Prof. José Firmo do Nascimento durante um mês. Participaram duas professoras de Biologia e dois alunos autistas do Ensino Médio. Após aprovação pelo Comitê de Ética e Pesquisa (CEP) sob o número 6.615.886, a análise dos dados revelou que adaptar estratégias de ensino é crucial para promover a inclusão de alunos com TEA. A P1 demonstrou um esforço significativo para adaptar sua metodologia às necessidades do Aluno 1 (A1), usando de forma implícita práticas baseadas na Análise do Comportamento Aplicada (ABA) e métodos inclusivos. Em contraste, a P2, apesar de sua experiência, usou abordagens mais tradicionais, não atendendo efetivamente às necessidades do Aluno 2 (A2). Assim, a P1 ajustou satisfatoriamente suas práticas para a AC, enquanto a P2 poderia melhorar personalizando suas metodologias e utilizando recursos mais compatíveis com as necessidades de aprendizado do A2.
Wash buffer 1 v1
Authors: Schmidt Anna , Patova Anya , Meyer Matthias
Published: December 2024

Protocol for the preparation of Wash buffer 1 (Fu et al. 2013), which is used in hybridization capture by the Ancient DNA Core Unit of the MPI-EVA. References Fu, Q., Meyer, M., Gao, X., Stenzel, U., Burbano, H.A., Kelso, J., Pääbo, S. (2013) DNA analysis of an early modern human from Tianyuan Cave, China. Proc Natl Acad Sci U S A. 110(6):2223-7. doi: 10.1073/pnas.1221359110
HWT buffer v1
Authors: Schmidt Anna , Patova Anya , Meyer Matthias
Published: December 2024

Protocol for the preparation of HWT buffer (Maricic et al. 2010, Fu et al. 2013), which is used in hybridization capture by the Ancient DNA Core Unit of the MPI-EVA. References Fu, Q., Meyer, M., Gao, X., Stenzel, U., Burbano, H.A., Kelso, J., Pääbo, S. (2013) DNA analysis of an early modern human from Tianyuan Cave, China. Proc Natl Acad Sci U S A. 110(6):2223-7. doi: 10.1073/pnas.1221359110 Maricic, T., Whitten, M., Pääbo, S. (2010) Multiplexed DNA sequence capture of mitochondrial genomes using PCR products. PLoS One, 16;5(11):e14004. doi: 10.1371/journal.pone.0014004
Dual Marginalisation and the Demand for Dual Citizenship: Negotiating “At Homeness” Among Diaspora Liberians
Authors: Vaughan Franka
Published: December 2024

In Liberia, identity and citizenship have long been contentious, with dual citizenship emerging as a focal point in recent decades. On 22 July 2022, former President George Weah signed an Amendment Law allowing Liberians naturalized abroad to retain citizenship and granting Liberian women the right to confer citizenship to their children, addressing a key demand from diaspora Liberians. This article, based on my doctoral thesis (Vaughan, 2022), examines diaspora Liberians’ advocacy for dual citizenship within contemporary debates on citizenship as a strategic institution. Drawing on the “post‐exclusive turn” in citizenship (Harpaz & Mateos, 2019), which suggests that individuals often prioritize a premium passport over strong ties to a homeland, the article explores how diaspora Liberians pursue dual citizenship to secure a “true home” in Liberia. This advocacy is fueled by their marginalization both in Liberia, where they face scrutiny over their Liberianness, and in their host countries, where they experience otherness as ethnic minorities. Dual citizenship, for these Liberians, is a strategic path back to belonging in Liberia. This article highlights the intricate interplay between identity and citizenship in Liberia, complicating the strategic citizenship framework by shedding light on the nuanced experiences of diaspora Liberians as they navigate dual marginalization and negotiate belonging. By focusing on these dynamics, the article contributes to the broader debate on citizenship in Africa, an area that remains understudied. Moreover, it reframes discussions on strategic citizenship, particularly in the context of growing inequalities and rising anti‐immigrant sentiments.
Treatment of elderly patients with acute myeloid leukemia: personal experience
Authors: Shimanovskaya L. T. , Misyurina E. N. , Baryakh E. A. , Zhelnova E. I. , Yatskov K. V. , Chudnova T. S. , Tolstykh T. N. , Gagloeva D. E.
Published: December 2024

Background. Acute myeloid leukemia (AML) is an aggressive malignancy of the hematopoietic system. Most patients with newly diagnosed AML are 65 years of age or older. Treatment of this cohort of patients is difficult due to the comorbidity of elderly patients and the genetic characteristics of hemoblastosis, which prevents the achievement of significant progress in treatment, in contrast to younger patients with AML. As domestic and foreign studies have shown, age is an independent universal prognosis factor for AML. In the era of targeted drugs, successful treatment of AML is becoming possible.

Aim. To assess overall survival in elderly patients with AML, tolerability and effectiveness of various treatment regimens in patients with AML ≥65 years.

Materials and methods. This paper presents our own experience in the treatment of elderly patients with AML in the hematology departments of the City Clinical Hospital No. 52. The study included patients over 65 years of age with AML from April 2022 to September 2023. A total of 40 patients were analyzed. To determine the risk factors for death, univariate and multivariate regression analyzes were performed using the logistic regression method. Variables that showed statistical significance on univariate analysis were included in the multivariate analysis. An analysis of 12‑month overall survival was also carried out using the Kaplan–Meier method with the construction of survival curves and calculation of median survival. A comparative analysis of two groups of patients treated with the AZA + EN and LdaraC regimens was carried out.

Results. 63 % (n = 25) are men, 37 % (n = 15) are women. The median age was 75 years; all patients had complicated premorbid background. 53 % (n = 21) of patients were in the age range from 65 to 69 years, 47 % (n = 19) were over 70. Antitumor treatment was received by 88 % (n = 35) of patients. The remaining 5 underwent: best accompanying (n = 2), cytoreductive (early death at this stage) (n = 3) therapy. Complete remission after two cycles of therapy was achieved in 46 % (n = 16) of patients, and in 29 % (n = 10) it was maintained at the time of analysis. Early relapse occurred in 14 % (n = 5). Early mortality was recorded in 9 % (n = 3). Death was reported in 40 % (n = 16) of patients. 20 % (n = 7) of patients were refractory to first-line therapy, of which 36 % (n = 5) were treated with low doses of cytarabine (LdaraC), the rest to a combination of azacitidine (AZA) with venetoclax (EN). The number of relapses among patients on AZA + EN and LdaraC therapy was comparable.

Conclusion. AZA + EN is the first-line treatment of choice in older patients with AML. The possibility of conducting this course in an outpatient setting makes it most convenient for both hematologists and patients. An important aspect in the treatment of AML in elderly patients is improving and maintaining quality of life.
THE RECEPTION OF ATHONITE HERITAGE IN UKRAINE (10th–16th CENTURIES)
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, BOGDASHEVSKYI Vladyslav
Published: December 2024

B a c k g r o u n d . This article is dedicated to a comprehensive study of the reception of Athonite heritage in Ukraine during the period from the 10th to the 16th centuries, which is a crucial element in understanding the spiritual, cultural, and social development of Ukrainian lands. Athos, as a center of Eastern Orthodoxy, played a key role in shaping monastic traditions that became the foundation for the development of monastic life in Kyivan Rus'. The author meticulously examines how the Athonite tradition, deeply rooted in Eastern Christian monasticism, influenced the establishment and functioning of Ukrainian monasteries, particularly the Kyiv Pechersk Lavra, which became a center of spiritual life and the spread of hesychasm in Ukrainian lands.

M e t h o d s . The article analyzes two main aspects of the reception of Athonite heritage: monastic and scholarly. The monastic aspect pertains to the influence of Athonite traditions on the organization and spiritual life of Ukrainian monasteries. The author demonstrates how Athonite practices, especially anchoritism, were transplanted to Ukrainian soil and adapted to local conditions. Special attention is given to the role of St. Anthony of Pechersk, who, having been tonsured on Athos, brought the core principles of Athonite monasticism to Rus', which shaped the subsequent development of ascetic traditions in Ukraine.

Results. The scholarly aspect encompasses the impact of Athonite spiritual ideas on Ukrainian philosophical and aesthetic thought. The author explores how the ideas of hesychasm, which originated on Athos, permeated Ukrainian lands through translated literature written by Athonite and Ukrainian monks. Significant attention is devoted to the influence of the works of Gregory Palamas and Gregory of Sinai, as well as other mystical-ascetic literature, on the formation of the spiritual worldview of Ukrainian scholars and theologians. The Kyiv Pechersk Lavra played a vital role in this process, being closely connected with Athos and becoming a center for the dissemination of hesychast ideas in Ukraine.

C o n c l u s i o n s . It is emphasized that the influx of the Athonite fall into the development of Cossack piety deserves special respect. It is shown how the Athonite monks, who arrived on the Ukrainian lands, molded the religious traditions of the Cossacks, promoting the ideas of twinning, lovelessness and the cult of the Virgin Mary as the patroness of Sich. Athonite ideals found their expression in the established Cossack monasteries and monasteries, which fueled the development of a special type of "Cossack piety", which became an invisible part of the national identity of Ukrainians.
ANALYSIS OF POPE FRANCIS'S STATEMENTS REGARDING THE RUSSO-UKRAINIAN WAR
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, KOSTIUK Oleksander
Published: December 2024

B a c k g r o u n d . The position of the Vatican regarding the Russian-Ukrainian war, its influence on international politics, and internal processes in Ukraine are being studied. The research examines the Vatican's diplomatic approach, which seeks to maintain neutrality and promote dialogue between the conflicting parties. An analysis of Vatican statements regarding the war in Ukraine, reactions to them from other countries and Ukrainian society has been conducted.

M e t h o d s . The study employs a complex of methods: historical analysis to examine the evolution of the Vatican's position (2014–2024), content analysis of Pope Francis's statements, comparative method to juxtapose different parties' stances, systems approach to consider the Vatican's influence on international and domestic politics of Ukraine, expert evaluation method, and statistical analysis of sociological data. This comprehensive approach allowed for a thorough investigation of the Vatican's position on the course of the Russo-Ukrainian war and its perception by the international community.

R e s u l t s . The study investigates the reasons behind the Vatican's position, such as the Catholic Church's pacifist doctrine, the desire to avoid unequivocal assessments, and the influence of Pope Francis's personal background and ideological views. The research also aims to clarify Pope Francis's influence on the internal political situation in Ukraine. Research period: 2014–2024, with a focus on two stages: 2014–2022 (hybrid war and local conflict); 2022–2024 (full-scale war). Main research results: The Vatican avoids calling Russia as an aggressor and does not condemn its actions. Pope Francis seeks reconciliation and proposes that the conflicting parties sit down for negotiations. The Vatican's position on the Russian-Ukrainian war is based on Catholic dogma, where evil does not have a substantive nature; the ideological views of Pope Francis (anti- Americanism, Latin American context); the general tendency in the Catholic Church towards forgiveness, laid down by John Paul II, and pacifism. The research reveals that the Vatican's stance has faced criticism from both Western countries and Ukrainian society, as it is perceived as equating the aggressor with the victim.

C o n c l u s i o n s . The Vatican does not have a significant influence on the decisions of world states. The position of the Bishop of Rome may influence public opinion in countries with a high level of religiosity. In Ukraine, the Vatican's position does not have considerable support from the Roman Catholic and Greek Catholic communities, and generally from Ukrainian citizens. The Vatican's position on the Russian-Ukrainian war is amorphous because it does not contain a clear moral assessment and equates the aggressor with the victim; therefore, criminal actions are condemned, but not their cause (Russia).
Development of a new bucket design for a single-bucket hydraulic excavator
Authors: Buriy Grigory G. , Poteryaev Ilya K.
Published: December 2024

BACKGROUND: Single-bucket hydraulic excavators are used in mining industry, construction industry, public utilities and other sectors of the economy. The productivity of these machines depends on a number of factors, among which the main one is the bucket volume.
Due to the impossibility of overcoming the digging resistance forces, it is impossible to install a larger bucket on an excavator of a certain category.
AIM: Development of the excavator bucket design, the shape and mechanics of which reduce digging resistance to make it possible to install larger buckets.
METHODS: The bucket model was built in the Kompas-3D software, and the APM FEM Kompas-3D application was used for strength calculations.
RESULTS: Sketches of the proposed buckets with a volume of 0.25 m³ are considered. The search for optimal parameters of the bucket parts to make it possible to install it on a production excavator and to perform the digging process was carried out. Justification of the parameters of the bucket parts is given. In order to check the operability, a strength calculation of the designed bucket structure was carried out. This will help to increase the productivity of the excavator and to expand its functionality.
CONCLUSION: As a result of the study, changes in the design of the production bucket, which make it possible to install buckets of increased volume on an excavator without losing the strength and reliability of the structure, were proposed. The strength calculation showed a safety factor of 3.3, which proves the operability of the designed structure of the proposed bucket.
Solutions for the preservation of injured teeth: a systematic review
Authors: Mitkina Ekaterina A. , Strelnikova Ekaterina V. , Gorbatova Maria A. , Shagrov Leonid L. , Grjibovski Andrej M.
Published: December 2024

Rationale: Traumatic dental injuries resulting from mechanical impact account for approximately 20% of oral and maxillofacial system diseases. Currently, the method of replantation presents a viable alternative to prosthetics and implantation. The success of replantation is largely determined not only by the speed at which the patient seeks dental care but also by the conditions under which the avulsed tooth is transported.

Objective: To search for and analyze scientific literature on solutions that can preserve the viability of teeth following traumatic injuries.

Materials and methods: PubMed and eLibrary databeses were utilized for the literature search. The review included studies that analyzed the biological properties of solutions used to maintain the viability of traumatized teeth. After screening and analyzing the full-text articles, 36 articles focused on comparing the efficacy of various transport media were included in the review.

Results: In the reviewed literature, we identified 34 different solutions, with their effectiveness evaluated by counting viable periodontal cells. The most frequently studied solutions were HBSS, various types of milk, propolis, and coconut water. The studies demonstrated significant differences in the effectiveness of the solutions used, storage conditions, and methods for diagnosing cell viability. Laboratory tests such as mtt and trypan blue were most commonly used to assess metabolic activity. HBSS and milk are the most effective media for preserving the viability of tooth tissues.

Conclusion: The research findings on the efficacy of solutions for maintaining the viability of cells in traumatized teeth highlight the need for the development of more accessible and effective transport media due to contradictory information regarding their biological effectiveness and indicate potential avenues for further research.
El convento de San Francisco de Ávila: aportaciones a su proceso constructivo y decoración
Authors: Moreno Blanco Raimundo
Published: December 2024

En el artículo se ofrecen datos inéditos desde la Edad Media al siglo XX. Se precisa la fecha de su primera aparición documental vinculándose a la fábrica primitiva del templo. En el proceso de adición de capillas, se atiende especialmente a aquellas en que intervino Juan Guas, proponiéndose nuevas relaciones que podrían ayudar a esclarecer su intervención en otras obras como el convento de Santo Tomás. Se aportan datos referidos al desaparecido claustro y sus dependencias durante la Edad Moderna, así como a su transformación en los siglos XIX y XX. Se plantea la hipótesis de la pertenencia de una pintura atribuida a Sansón Florentino a la capilla de San Antonio y se dan a conocer desaparecidos retablos inéditos junto a sus autores.
Analysis of Factors Affecting Household Food Consumption Away From Home in Türkiye
Authors: Akbay Cuma , Bilgiç Abdulbaki , Paksoy Mücahit
Published: December 2024

One of the most important changes in consumer food consumption habits in recent years is the trend toward food consumption away from home (FAFH). The effects of socioeconomic and demographic factors on FAFH expenditure and consumption decisions were jointly investigated using the inverse hyperbolic sine double-hurdle (IHS-DH) model, and household survey data consisting of 1655 consumers in 14 cities in Türkiye. According to the results, the consumer being a male, having a high school or university diploma, an extra person generating income outside the family head, having children under the age of 18, and having high income increased the likelihood of consuming FAFH. However, the probability of FAFH consumption spending decreases with the variables of the consumer age, seasonal variables, geographical regions, and family size. On the other hand, consumers’ unconditional FAFH consumption expenditure increases when the variables of male, high school or university diploma, internet, children under the age of 18, and visiting shopping centers frequently. However, the presence of regular meals in the family decreases FAFH consumption. This research sheds light on the nuanced interplay of various socioeconomic and demographic factors shaping consumer behaviors regarding FAFH consumption, thereby offering valuable insights for policymakers and stakeholders in the food industry.
Garantías y transformaciones en el derecho civil de los negocios: el caso de las garantías mobiliarias
Authors: González León Carlos Andrés
Published: December 2024

The present work is an advance result of investigation in which it is exposed how the traditional conception of the Civil Security Rights has been affected from the legal framework on Law of Propietary Security Rights in Colombia. For its construction, a review was made of the elements that the dogmatics of private law has recognized in order to identify the concept of guarantee against the legal reform that sought to homogeneously systematize the regulation on the matter. The findings are based on the review from legal dogmatics, from documentary sources in order to make an analytical study of them, the result allowed to classify and establish comparison parameters.
Herramientas de intervención social para la paz en zonas fronterizas y vulnerables, desde las metodologías agiles
Authors: Velásquez Pérez Torcoroma , Castro Silva Hugo Fernando , Flórez Villamizar Libardo
Published: December 2024

The social conglomerate in recent times has been affected by macro policies, the economic interests of government entities, and undoubtedly by the avalanche of changes and transformations that in one way or another have impacted society. The case that is unveiled in the diaspora in Venezuela due to the economic crisis that has arisen in recent years. The reason that opens the possibilities to generate actions that contribute in some way to face this situation; Hence, the present investigative work focuses on proposing some social intervention tools for peace in border areas and high vulnerability, from agile methodologies, in the context of the border axis Cucuta, Villa del Rosario - Colombia and San Antonio del Táchira - Venezuela. The research was framed in a mixed methodology under the sequential approach in order to have an approach to reality and be able to generate social transformation.
Análisis exploratorio del contenido de las capitulaciones en Popayán durante los años 2016 a 2019
Authors: Garcés Garcés Hugo Alexander , Urrutia Bolaños Jessica Alejandra , Rojas López María Fernanda , Gómez Mesa David Alejandro , Ruíz Dorado Yohana María , Álvarez Gómez Andrés Fabián
Published: December 2024

To analyze the content and legal effectiveness of the legal business in the matrimonial and marital contracts made in Popayán, from years 2016 to 2019, an analytical methodology was applied, as well as the study of some relative legal categories for the capitulant contracts and the private autonomy in matrimonial and common-law marriages area. The analysis is developed from a historical perspective using scientific, doctrinal and jurisprudential sources. Once the subject dogmatics has been revised, the information obtained is compared with the observation of public deeds signed during the indicated period. It will be revealed how the legal regulation of the capitulant contracts is incipient and many contractual clauses analyzed end up being ineffective or unnecessary in the light of legal provisions. Findings of great importance as the contractualization of family relationships become increasingly necessary and require greater clarity on how to prepare this type of legal business.
Los efectos de la vacuna contra el Covid-19 y la responsabilidad extracontractual del Estado: régimen y fundamento de responsabilidad
Authors: Granados Alfonso Dubán Arturo , Jiménez Escalante Jessica Tatiana
Published: December 2024

The pandemic caused by the SARS Cov-2 virus, better known as Covid-19, brought with it multiple social, political, economic and, of course, legal challenges. In the latter, the challenges have been relevant from various perspectives, such as measures adopted by the State in the face of the health contingency or the changes in procedural matters that led the judicial process to virtuality, always being present the right to damages, specifically, from the non-contractual liability of the State that may arise on the occasion of the vaccination processes for the immunization of the Colombian population, provided for in Law 2064 of 2020 (Law 2064, 2020), a rule with which multiple obligations arise for the State and from which some conditions can be identified regarding the eventual claim and declaration of responsibility based on proof of the existence of damage caused to citizens within the framework of said process, therefore, in this The investigation intends to address one of the initial and most relevant components of responsibility, the one related to the regime and the basis or title of applicable imputation, for which some aspects of the other elements that make up the judgment of responsibility are analyzed. All of the above, based on a historical-normative and historical-jurisprudential analysis of immunization processes carried out in the country.
El Impacto del Principio de Inembargabilidad de los Recursos del Sistema de Seguridad Social en Salud frente al Derecho a la Tutela Judicial Efectiva en Colombia
Authors: Castaño Quijano Juan Manuel
Published: December 2024

The aim of this article of legal reflection is to determine the impact of the principle of the unseizability of the resources of the general social security health system on the right to effective judicial protection in Colombia. For this purpose, a qualitative legal research of a descriptive nature was carried out, using documentary and bibliographic techniques such as documentary, normative and jurisprudential analysis files, the results of which were studied from the teleological and systematic hermeneutics, which are aimed at determining the purpose of a complex set of norms.
 
With this, the structure of the General System of Social Security in Health in Colombia and the legal nature of its resources were identified, the Principle of Unattachability of Resources of the Social Security System in Health was studied, and the maxim of effective judicial protection in Colombia was examined. It was concluded that, while there is a general rule on the unseizability of health resources, there are also precise exceptions that must be applied in judicial practice in order to guarantee effective judicial protection. However, there is still a problem of non-compliance with the exceptions by the judiciary and administrative bodies.