bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring Redevelopment and Police Presence in Bushwick, Brooklyn, Using Photovoice Methodology
Authors: Colvin Ayana
Published: May 2024

The relationship between redevelopment and police presence is demonstrated in many neighborhoods by the influx of new residentsfrom suburban or rural areas and shifts in police response. As property values increase, police may prioritize order maintenance policing, also known as "broken windows" policing (Beck, 2020, p.247). This is disproportionately felt by Black and Brown residents who often suffer the consequences of rising costs, displacement, increased surveillance, and police presence. This paper explores the relationship between urban redevelopment and policing in one of the most popular neighborhoods in the borough of Brooklyn–Bushwick. As a socialwork researcher of color, I want to share the narratives that often go overlooked. I felt secure and empowered to conduct research and report my findings as a community member who is seeking to support and collaborate with my community. Photovoice allows me to do just this by highlighting the daily realities in my neighborhood. However, having more voices from long-term community members is imperative and will be essential in further exploration of this topic.
Keywords: gentrification, redevelopment, policing, police presence, Bushwick, Brooklyn, New York City, photovoice, etc.
Identitet, stradanje, sjećanje i asimilacija Srba na području Grubišnog Polja i Bjelovara
Authors: Škiljan Filip
Published: May 2024

Autor na temelju usmenih iskaza prikupljenih na terenu na području Bilogore između Bjelovara i Grubišnog Polja i objavljene literature, donosi informacije o nekim bitnim identitetskim obilježjima Srba koji žive na tom području (običaji oko rođenja djeteta, vjenčanja, smrti, o vjerskim običajima i krsnim slavama). Potom istražuje koji su faktori utjecali u socijalističkom razdoblju na povećanu asimilaciju Srba (antifašistička borba i sjećanje na nju, jugoslavenstvo, ateizacija i slično). Posebno se bavi sjećanjima na prošli, Domovinski rat (1991. — 1995.) i na stradanja stanovništva Grubišnog Polja i bjelovarskog kraja u tome ratu.
Jugoslavija ili Balkanska federacija?
Authors: Gužvica Stefan
Published: May 2024

Do proleća 1917. godine, na teritoriji (bivšeg) Ruskog carstva našlo se nekoliko desetina hiljada ratnih zarobljenika Južnih Slovena, od kojih su se mnogi direktno uključili u revolucionarna događanja započeta padom monarhije u februaru. Nakon Oktobarske revolucije, hiljade Bugara, Hrvata, Slovenaca i Srba borile su se na strani boljševika. Od 1918. godine, imali su svoju Južnoslovensku komunističku grupu pri Boljševičkoj partiji, kao i novine Svetska revolucija. Grupa se, međutim, brzo sukobila po pitanju ustrojstva posleratnog projekta. Jedni su se zalagali za stvaranje Jugoslavije kao države Južnih Slovena, dok su drugi smatrali da buduća socijalistička država treba biti Balkanska federacija, stari projekat balkanske socijaldemokratije. Ovo neslaganje dovelo je u konačnici do odvajanja Bugara iz Južnoslovenske komunističke grupe. Iako pitanje buduće radničke federacije na Balkanu nije razrešeno čak ni formiranjem Komunističke internacionale, ova zaboravljena rana debata između tada vodećih južnoslovenskih komunista bila je uvod u kasnije marksističke rasprave o nacionalnom pitanju u Bugarskoj i Kraljevini SHS. Analiza ovih projekata otvara pitanja o prijemu boljševičkih ideja među Južnim Slovenima, kontinuitetu i diskontinuitetu marksističke misli među balkanskim socijalistima pre i posle 1917. godine, kao i o razvoju koncepta lenjinističkog prava na samoopredeljenje u kontekstu političke situacije na Balkanu u posleratnom periodu.
Mortality from Infections Associated with Health Care in Patients with HIV in Paraguay
Authors: Lopez Gladys , Aguilar Gloria , Rios-González Carlos Miguel
Published: May 2024

Introduction: Few studies have evaluated HAIs in an HIV population; however, studies have suggested that patients with HIV are at a higher risk of contracting HAI because they have high rates of hospitalization and longer hospital stays. Objective: To determine mortality due to Infections Associated with Health Care in Patients with HIV in Paraguay from January to December 2018 to 2021. Methodology: This was an observational, descriptive, and cross-sectional study. The study population consisted of people over 18 years of age who died with a diagnosis of HIV infection and IAAS of both sexes during that period. The study variables were demographic, HIV-related, Baseline Viral Load, Stage of HIV infection at the time of diagnosis, Time from HIV diagnosis to death (in months), comorbidities at the time of death, microorganism isolation, presence, and location. of IAAS. Results: 93 patients with IAAS were included in the study, of which 34.4% (32) were between 20 and 29 years of age and 19.3% (18). Regarding the type of population, 79.3% (73) were in the general population, 77.6% (59) were diagnosed with AIDS, and 68.6% (59) had a baseline CD4 count of less than 200 cells/mm3. The mortality rate in 2020 was 6.7%, during 2018 it was 6.5% and in 2021 it and 6.4%. Conclusion: People with HIV, especially those who have been diagnosed in advanced stages of the disease, are more likely to develop HAIs and are related to mortality. This is due to the presence of multiple opportunistic infections and comorbidities that favor a high number of hospitalizations and longer hospital stays.
Resilience as a Modulating Factor of Empathy in Medical Students
Authors: Acosta-Martínez Adán A. , Sandoval Mildred A. , Monterroza Leida G. , Reyes-Reyes Fernando , Reyes-Reyes Alejandro , Vilca Lindsey W. , Díaz-Narváez Víctor
Published: May 2024

Introduction: Empathy is a complex and multidimensional attribute. Attempts have been made to explain empathic behavior based on other variables. Empirical evidence shows that empathy could be the product of the influence of several factors. One of these factors could be resilience. There is still no developed theory and consistent empirical evidence demonstrating that empathy depends on resilience. Objective: The aim of this study is to determine if resilience can predict empathic behavior. Methodology: This study is non-experimental and ex post facto with a cross-sectional design. Variables. Dependent: Empathy; Independent: Resilience. Population: Medical students belonging to the Faculty of Health Sciences of the Universidad Autónoma de Santa Ana (UNASA), Santa Ana, El Salvador (N=579). The sample (n=465) consisted of students (both sexes). Convenience sampling. Jefferson Scale of Empathy for Healthcare Professionals, student version (JSE-HPS). Trait Resilience Scale (EEA). A Structural Equation Modelling (SEM) model was used. Additionally, the Comparative Fit Index (CFI) (>0.95), Tucker-Lewis Index (TLI) (>0.95), Root Mean Square Error of Approximation (RMSEA) (<0.08), and Standardized Root Mean Square (SRMR) (<0.08), Confirmatory Factor Analysis (CFA) were employed. The significance level employed was ? < 0.05. Results: All these results show that both measurement models (empathy and resilience) are adequately represented and are suitable for the structural model. Discussion: Individual resilience is a variable that can predict empathic behavior in medical students belonging to a Faculty of Health Sciences. The results constitute indirect empirical evidence that it is possible to define empathy as a dependent variable and resilience as an independent variable.
Scientific research in the professionalization of staff didactic: relevance, performance, excellence and values
Authors: VICOL Nelu
Published: May 2024

The text is conceptualized in the context of the government’s strategic policies in the field of education. In this sense, the State Program 2020-2023 was developed in the field of research and innovation of certain state priorities. The author, together with the members of the research team, carried out the scientific-methodological and praxiological activity within the Project „Foundation of the professionalization paradigm of teachers in the context of societal challenges”, focused on the fourth strategic priority „Societal challenges”. However, the text of the article reveals the relevance, performance, excellence and values of the scientific research results obtained within the project in the period 2020-2023.
The axiological dimension of the current curriculum and the educational reality
Authors: HADÎRCĂ Maria , PRISECARU Luminița
Published: May 2024

This article highlights the axiological dimension of the current curriculum, analyzes in a comparative manner (as regards Romania and R. Moldova) the essential elements and characteristics of this dimension in the context of: a) the national curriculum; b) the curriculum for Romanian Language and Literature for high-school education; c) the educational reality which requires the full validation of educational values; and also puts forward some proposals to remedy the situation.
The reading process, fluence and comprehension
Authors: FLUERAȘ Vasile
Published: May 2024

The process reading is actually a complex interaction between the text and the reader, the latter being shaped by the text he reads and perceives through the lens of personal experiences, values and the culture of the society he represents. The reading process, fluency and understanding are interconnected with the aim of forming the reflexive reader.
The procedual end systemic approach of musical-didactic activities at the music education lesson
Authors: CALIGA Marina
Published: May 2024

This study investigates the concept of activity in the systemic approach of musical-didactic activities at the music education lesson. The activity is not a totality of reactions, it is a system, which has its own structure, content, changes and internal transfers, aiming personal development of the personality. Through activity, person produces changes in objective external conditions, in his own internal states, in relations with the environment. In activity, person realizes his ideas, satisfies his aspirations, builds new plans, new ideals; through activity, person adapts to internal and external conditions, at an increasingly higher level. Based on the Education Reform in the Republic of Moldova, the approach and systematization of musical-didactic activities at the music education lesson have been implemented in musical practice for several years. The curricular reform involved a substantial change in the instructive-educational process, a new teaching model being proposed, which would allow students to form a unified conception of musical art.
Prevalence of De Quervain's Tenosynovitis among Restaurant Station and Junior Chef using Physical Assessment Test
Authors: Dinodia Kashish , Singh Sushmita , Kumar Ajay
Published: May 2024

Aim: -To find the prevalence of De Quervain’s Tenosynovitis among restaurant Station and Junior chef.
Objective: -To find presence of De Quervain’s Tenosynovitis among Restaurant Station and Junior chef using Finkelstein test.
Methodology: -144 subjects were selected from the metropolitan cities according to the inclusion and exclusion criteria. A written informed consent was taken from the subjects in the language best understood by them. The study subjects were explained about the procedure. The test is performed on both the hands. A positive test is indicated by pain over the abductor pollicis longus and extensor pollicis brevis tendons at the wrist. The data was collected and was statistically analyzed.
Statistics and Results: -Total 144 chefs were included in the study out of which 20 chefs were indicated for the De Quervain's Tenosynovitis i.e. 13.9% of the total population was positive.
Conclusions: - The study concluded that De Quervain's Tenosynovtis is less prominent among Station and Junior Chef.
Clinical Implication: this study can be used to make people aware and prevent the occurrence or worsening of existing De Quervain’s tenosynovitis. People can be given ergonomic advice like taking frequent breaks while working and resting the hand.

Key words: DeQuervain’s Tenosynovitis, Chef, Finkelstein test, Musculoskeletal disorder.
Performance Based Disability Associated with Kinesiophobia and Self-Efficacy Among Older Adults
Authors: P Patel Neha , Suvagiya Suhasi , Singh Kanika
Published: May 2024

Purpose of study: Disability and kinesiophobia which represent a participant's perception of his/her own function and activity. Self-efficacy has also been found to act as a mediator of changes in health behaviors and in use of the healthcare system. Less research published on the associations among the extent of performance-based disability, kinesiophobia and self-efficacy among older adults.
Methodology: This observational analytical study included 142 older adults who lived independently in the community. Written informed consent was taken from those willing to participate and fulfilling inclusion and exclusion criteria were included in the study. Each older adult’s individual performed short physical performance battery (SPPB), kinesiophobia measured by Tampa scale for kinesiophobia -11 (TSK -11). Self-efficacy measured by generalized self-efficacy scale (GSE). Each subject was given appropriate rest period between all tests.
Results: In present study moderate negative association between performance-based disability and kinesiophobia in older adults (r=-0.537, p<.001), performance-based disability and self-efficacy in older adults (r=0.436, p<.001), between kinesiophobia and self-efficacy in older adults (r= -0.420, p<.001).
Conclusion: The findings indicate that negative association between performances-based disability and kinesiophobia, between kinesiophobia and self-efficacy in older adults. Positive association between performances-based disability and self-efficacy in older adults.

Key words: Disability, Kinesiophobia, Older adults, Self- efficacy
Incidence of Musculoskeletal Injuries in Rope Mallakhamb Players and Associated Risk Factors
Authors: Arun Bankar Shravani , Yeole Ujwal
Published: May 2024

Background: Mallakhamb is a traditional sport originating from India and gained worldwide recognition on the sidelines of Berlin Olympics held in the year 1936. The sport of Mallakhamb was originally practiced to develop the strength, agility and flexibility of wrestlers and has now developed into a sport with championships held annually at District, State and National levels throughout India. Understanding the prevalence and nature of injuries in Rope Mallakhamb is crucial for development of effective injury prevention strategies, training protocols, and rehabilitation approaches.
Purpose: To evaluate incidence of musculoskeletal injuries in rope mallakhamb players and identify associated risk factors.
Objective: To determine Incidence of different type of musculoskeletal injuries in rope mallakhamb players. To evaluate associated risk factors.
Setting: Rope Mallakhamb practice centers in Pune.
Method: We carried out a cross sectional study in 60 athletes who were engaged in the game of Rope mallakhamb and had experience of more than one year. A pre designed questionnaire was circulated among the players via google forms and players were asked to fill the form to the best of their knowledge.
Participants: Age group 15-30 years were taken for the study. Players with experience of less than one year were excluded from the study.
Outcome measure: The primary outcome measure of this study was a pre designed sports specific questionnaire.
Results: In upper limb most, common injuries were wrist fractures (10%) followed by wrist sprains (8%) then forearm fractures, (6%) finger dislocation (6%), elbow dislocation (2%). In lower limb calf strain was most common injury (14%) followed by ankle sprain (12%), ankle fracture (8%), hamstring strain (8%), toe dislocation (8%) and knee joint fractures (6%). In trunk most common injury reported was back sprain (12%) of all the reported injuries.
Conclusion: This study concluded that the incidence of strain and sprain injuries is most common with involvement of distal joints of upper and lower extremities.

Key words: Rope mallakhamb, Sports injuries.
Fedpol muss nicht offenlegen, ob ein Vertrag mit einem GovWare-Entwickler besteht
Authors: Rahel Breitschmid Anna Katharina Burri und
Published: May 2024

In den Medien wurde bekannt, dass Schweizer Behörden israelische Überwachungssoftware (sog. GovWare) einsetzen würden. Ein Gesuchsteller beantragte gestützt auf das Öffentlichkeitsgesetz (BGÖ) beim Bundesamt für Polizei (fedpol) Zugang zum Vertrag mit der israelischen NSO Group über die Nutzung jeglicher von dieser entwickelten Software. Das fedpol verweigerte die Information über die Existenz oder Nichtexistenz eines solchen Vertrages. Diese Verweigerung beurteilt das Bundesverwaltungsgericht als rechtmässig. Öffentliche Interessen würden dem Zugang entgegenstehen: Rückschlüsse auf die verwendete GovWare könnten behördliche Massnahmen beeinträchtigen und die Sicherheit der Schweiz gefährden. Allenfalls nutze auch der Nachrichtendienst des Bundes (NDB) die GovWare, womit das BGÖ nicht anwendbar wäre. Gegen das Urteil des Bundesverwaltungsgericht ist ein Beschwerdeverfahren vor Bundesgericht hängig.
Collective Security and the African Regional Integration
Authors: S. E. N. Ebaye , S. O. Okputu
Published: May 2024

The end of the cold war and the marginalization of Africa, coupled with the vicious cycle of poverty, underdevelopment, disease and internecine conflicts are reasons for the aggressive support for African regional integration and security mechanism. Meanwhile, commitments to African regional integration have been constrained by a highly ambivalent critique of the colonial heritage of sovereignty, and unwilling to transfer any of such freedom to supra-national bodies. Yet this has the potential of enhancing their ability to coordinate the implementation of collective security. The objective of this research therefore is to place the relationship between the African regional integration and the efficacy of collective security within the region. The study adopted the Survey research design. The main instrument for data collection was structured questionnaires. The Spearman rank order correlation coefficient was used in testing the hypothesis at 0.05 level of significance. Findings revealed that, there is a significant relationship between African regional integration and collective security/ effective deterrent to aggression, and also that, there is a significant relationship between the failure of African regional integration and the security dilemma confronting the region. The researcher therefore recommends that for the purpose of conflict management, the partnership between the UN and the AU, with its corresponding sub-regional organizations, should be akin to a pyramid. Regional security integration should rest on concepts of good governance, sound civil-military relations and commitments to democracy and human rights, and that regional security arrangements need to focus on modest measures for the prevention and containment of conflicts, rather than utopian ideas and complex institutional mechanisms.
Dreams and Grief Process in Selected Communities in Africa
Authors: S. Asasta, , U. K. Agwu, , C. Nkoma, , B. S. Cordeiro, , L. R. Machogu, , T. F. Koffi, , D. Nyangoya,
Published: May 2024

Death is as old as life itself. The unpredictable psychological feeling called grief is usually accompanied by emotional setbacks such as anxiety, depression, insomnia, and yearning. Within these emotions also lie the reality of dreaming about the deceased. Thus, this study aimed to assess the role of dreams in grief process among selected communities in Africa and was guided by Nyerere’s philosophy of Ujamaa. The study used a phenomenological design with a sample size of 31 respondents from the Igbo (Nigeria), Tabwa (Democratic Republic of Congo), Muganda (Angola), Agni Morofoue (Cote D’ivoire), Luo (Kenya) and Gusii (Kenya) cultures. The results of the study were interpreted using content analysis. The findings showed that dreams served the roles of comfort, encouragement, warning, revelation, and spiritual presence during grief process. The results also showed that dream images can be interpreted in three ways; positively, negatively or altered image interpretation, each having its emotional effects. Prayers, purification, libations, and ritualistic sacrifices are some of the communal healing techniques for dreams having a negative image interpretation. The study therefore recommends that detailed analysis be combined with empathetic intuition and creative imagination in dream interpretation as many African communities place great importance on dreams.
Health Risk Associated with Conventional Skin Lighteners and Female Civil Servants’ Comprehension of Skin Lightening Ingredient Information in Anambra State
Authors: N. A. Allen , E. C. Obi
Published: May 2024

Skin-lightening products have been in use for many years to lighten skin colour. However, these products contain chemicals that can alter the skin's chemical structure and inhibit the production of melanin. Therefore, users of these products need to understand the ingredients and the potential health risks associated with their use. A study was conducted to assess the health risks associated with conventional skin-lightening products and to determine how well female civil servants understood the ingredient information on the product packaging. The study aimed to determine how many women read the ingredient information on these products, how many understood the information, and how many were aware of the health risks associated with their use. The study was conducted as a survey of 348 civil servants from 21 Ministries in Anambra State using an online sample size calculator. The study was anchored on the Individual Difference theory and selective perception media effect. The survey found that a significant number of female civil servants in Anambra state do not read the ingredient information on skin-lightening products. It was also discovered that the majority of female civil servants in Anambra State do not comprehend the product ingredient information because of its technical nature. Despite this, the study found that most women were aware of the health risks associated with the use of these products. The study concluded that female civil servants in Anambra State were aware of the ingredient information composition on skin-lightening products, but did not read it, making it difficult for them to understand and interpret the information. However, most of these women were still aware of the health risks associated with the use of skin-lightening products but still used them because of the benefits they claimed to have experienced. The study recommended that manufacturers and brand designers should simplify the technical language used to describe the product ingredients to make it easier for users to understand. Additionally, regulatory agencies like NAFDAC and SON should ensure that manufacturers produce skin products that do not contain harmful chemicals like hydroquinone, corticosteroids, and mercury. If these chemicals are used, users should be informed of the negative side effects.
From Myelodysplastic Syndrome to Myelodysplastic Neoplasm: The Impact of WHO's Reclassification on MDS Research
Authors: Gusmão Jonas Nogueira Ferreira Maciel , Carneiro Diego Thiers Oliveira , Ribeiro-Junior Howard Lopes
Published: May 2024

This letter addresses the challenges posed by the recent reclassification of Myelodysplastic Syndromes (MDS) to Myelodysplastic Neoplasm (maintaining the acronym MDS) by the World Health Organization (WHO). Despite the clinical and scientific justification for this change, the adoption of the new terminology in the research community has been slow, leading to decreased visibility and citation of studies using the updated nomenclature. Here, it was proposed a gradual transition where both terminologies are used simultaneously in research articles to maintain research visibility while educating the medical community about the new terminology. Furthermore, it is suggested that major databases and search engines update their algorithms to link both terms, ensuring comprehensive search results. The role of international medical societies and scientific journals in promoting the use of the new terminology is also emphasized.
La experiencia de atender las señales del cuerpo: Bases neurofisiológicas de la relación entre la atención interoceptiva y el reconocimiento emocional.
Authors:   ,   Universidad del Desarrollo, Pizarro Cordero Claudia
Published: May 2024

Internal body processes give rise to signals that are perceived and integrated by the brain, generating an instantaneous monitoring of the internal body state in a process called interoception, differentiated from attention to external signals (exteroception). The overall objective of the present study was to characterize at the physiological and behavioral level the relationship between interoceptive attention and emotional recognition. Behavioral analyses of the first experiment indicate that the presentation of emotional stimuli did not have an enhancing effect on performance in interoceptive recognition tasks. Although interoceptive processes are related to emotional processes, the relevant dynamic is one of attentional compensation. In this sense, based on this idea the behavioral results of the second experiment suggest that the differences in performance on emotional recognition tasks according to attentional focus were specific to the emotional recognition task on faces. Whereas the EEG data distinguished between interoceptive and exteroceptive attentional processes, particularly during the early phase (P100) only for the emotional face recognition tasks. The group without attentional focus demonstrated greater accuracy in their responses compared to the group with exteroceptive focus at the behavioral level. In conclusion, the interrelationship between emotion and interoception is influenced by attention, especially during the initial phases of perceptual processing, as evidenced by the EEG findings. An unbalanced allocation of attentional resources could lead to emotional dysregulations and perceptual errors, contributing to physical symptoms associated with perceptual noise or could decrease attention to introspective emotions and affect empathy towards others. A new model is presented that illustrates the linking process between the external representation of salient stimuli and the internal state, highlighting the importance of attention in this connection.
Post and Core Restorations – CAD/CAM vs. Conventional Methods
Authors:   Department of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University – Plovdiv, 4000 Plovdiv, Bulgaria., Dimitrova Mariya , Kazakova Rada ,   Department of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University – Plovdiv, 4000 Plovdiv, Bulgaria.
Published: May 2024

The aim of the current paper is to review the available literature reporting on studies of post and core restorations in terms of their composition, fabrication techniques, and clinical performance. The methodology included applying a search strategy, defining inclusion and exclusion criteria, and selecting studies to summarize the results. Searches of PubMed, Scopus, and Embase databases were performed independently by three reviewers to gather literature published between 2000 and 2023. A total of 124 titles were obtained from the electronic databases, and the application of exclusion criteria resulted in the identification of 26 articles pertaining to conventional and CAD/CAM technology for post and core restorations. Several ways for restoring endodontically treated teeth with CAD/CAM post and cores have been published, including direct and indirect procedures. The most often reported materials were zirconia, composite resin, and hybrid ceramic. There are few published studies on CAD/CAM post and core; however, more research is needed to study the long-term outcome of this treatment.
Advantages of Additive Manufacturing for Complete Removable Dentures
Authors:   Department of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University – Plovdiv, 4000 Plovdiv, Bulgaria., Dimitrova Mariya , Vlahova Angelina ,   Department of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University – Plovdiv, 4000 Plovdiv, Bulgaria., Kazakova Rada ,   Department of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University – Plovdiv, 4000 Plovdiv, Bulgaria.
Published: May 2024

The purpose of this review is to examine the existing body of research regarding complete 3D-printed dentures. This examination will cover new biomaterials, methods of creation, workflow, how well they work in clinical settings, and the contentment of patients using them. The methodology involved implementing a search plan, establishing criteria for inclusion and exclusion, and picking out relevant studies. Four reviewers conducted separate searches on PubMed, Scopus, and Embase databases to collect articles released from 2002 to 2023. From the electronic database, a sum of 116 headings was acquired, and after implementing exclusion criteria, 28 articles were pinpointed relating to technology for creating full dentures through printing. Present advancements and progress in digital dentistry have effectively enabled the production of removable dental prostheses through CAD/CAM technologies.
Novel hemostatic gel used in bleeding esophageal ulcer to promote mucosal healing
Authors:   Clinical Associate Professor of Medicine, G.I. Fellowship Program Director, Chief of Endoscopy at Ascension, St. John Hospital, Wayne State University, USA., Barawi Mohammed , Rehana Rita W ,   Clinical Associate Professor of Medicine, G.I. Fellowship Program Director, Chief of Endoscopy at Ascension, St. John Hospital, Wayne State University, USA.
Published: May 2024

Intraprocedural bleeding during endoscopic intervention, gastrointestinal bleeding, or bleeding tumors can be treated with many different modalities such as heat therapy, endoclipping, or embolization. One alternative option that has been proven in literature to be safe and effective is PuraStat, which is a novel self-assembling peptide used for hemostasis during endoscopic procedures such as polypectomies, submucosal dissection, and mucosal resection. This matrix-forming gel can be easily and safely applied to prevent delayed bleeding, accomplish hemostasis and effectively promote mucosal healing. Our case represents a patient who presented with active upper gastrointestinal bleeding that achieved hemostasis and wound healing with the use of PuraStat.
Surgical Management of Epilepsy and Outcomes in a Comprehensive Epilepsy Center in Pakistan: A 20-year Retrospective Analysis
Authors:   Aga khan University and Hospital, Karachi, Pakistan., Imtiaz Hina , Khan Ayisha Farooq ,   Aga khan University and Hospital, Karachi, Pakistan., kanwar Dureshahwar ,   Aga khan University and Hospital, Karachi, Pakistan., Siddiqui Fowzia ,   Aga khan University and Hospital, Karachi, Pakistan., Wasay Mohammad ,   Aga khan University and Hospital, Karachi, Pakistan.
Published: May 2024

Background: Epilеpsy is a prеvalеnt nеurological disordеr in Pakistan, with an еarly onsеt in a substantial portion of thе population. Surgical intеrvеntion for drug-rеsistant еpilеpsy is a viablе trеatmеnt option, yеt it rеmains undеrutilizеd duе to limitеd spеcializеd cеntеrs and sociеtal stigmas. Objectives: Our study evaluated thе outcomеs of еpilеpsy surgеriеs pеrformеd ovеr two dеcadеs in a major Pakistani hospital. Mеthodology: A 20-yеar rеtrospеctivе cohort study was conductеd from 2002 to 2022, involving 31 patiеnts with focal еpilеpsy who undеrwеnt surgical procеdurеs. Patient demographics, clinical history, electroencephalogram (EEG) and magnetic resonance imaging (MRI) findings, and surgical interventions were recorded. Data analysis was pеrformеd using SPSS vеrsion 23. Rеsults: Among thе 31 patiеnts, thе majority had intractablе sеizurеs, and 14 wеrе on thrее or morе anti-еpilеptic drugs prеopеrativеly. Surgical procеdurеs includеd sеlеctivе amygdalohippocampеctomy, tеmporal lobеctomy, corpus callosotomy, lеsionеctomy, craniotomy, and hеmisphеrеctomy. Postsurgical complications wеrе minimal. Around 32.3% of the patients achieved complete seizure freedom at 6 months, and 45.2% at 1 year. Conclusion: Surgical procеdurеs, including tеmporal lobеctomy and corpus callosotomy, havе shown promisе in achiеving sеizurе frееdom or significant improvеmеnt in sеlеct casеs. Thе findings еmphasizе thе critical nееd for timеly diagnosis and carеful patiеnt sеlеction. Rеcognizing еpilеpsy’s impact on both physical and psychosocial wеll-bеing emphasizes thе importancе of considеring surgical options whеn consеrvativе thеrapiеs provе inеffеctivе. Incrеasing awarеnеss and accеssibility to spеcializеd еpilеpsy cеntеrs arе еssеntial stеps toward improving thе managеmеnt of еpilеpsy in developing countries.
Pathomorphology of Metastatic PitNET/Pituitary Carcinoma with Cerebral Dissemination: Autopsy Case Presentation
Authors:   Polenov Neurosurgical Institute – Branch of Almazov National Medical Research Centre, 197341 St. Petersburg, Russia., Sitovskaya Darya , Verbitskiy Oleg ,   City Mariinskiy Hospital, 191017 St. Petersburg, Russia., Petrova Yulia ,   City Mariinskiy Hospital, 191017 St. Petersburg, Russia., Zabrodskaya Yulia ,   Polenov Neurosurgical Institute – Branch of Almazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Published: May 2024

Metastatic PitNET(mPitNET) is an extremely rare tumor of neuroendocrine cells of the adenohypophysis with craniospinal and/or systemic metastases and a poor prognosis. The pathogenesis of mPitNET/pituitary carcinoma is not completely clear. Several developmental models have been proposed, including sequential tumorigenesis and de novo transformation. Metastatic PitNETs have been reported in patients with germline tumor predisposition to neoplasia including SDHB mutation and Lynch syndrome. We report a fatal case of a 68-year-old female patient with a third recurrence of null cell PitNET and cerebral dissemination to the pia mater, infiltrative growth into the chiasm, and micro metastasis into the occipital lobe.
Smart Circuit Design Machine Learning-Driven Optimization for Enhanced Performance in Electronics and Computer Engineering.
Authors: Purushottam Kumar Maurya
Published: May 2024

In the realm of Electronics and Computer engineering, achieving optimal performance of circuits amidst escalating complexity poses significant challenges. Traditional manual optimization techniques are often inadequate to navigate the intricacies of modern electronic systems. This paper advocates for the adoption of machine learning-driven optimization as a transformative approach to smart circuit design. By leveraging machine learning algorithms, engineers can systematically explore the expansive design space, discern complex relationships between circuit parameters and performance metrics, and ultimately enhance the efficiency and effectiveness of electronic circuits. This paper comprehensively reviews the application of machine learning techniques in circuit design optimization. Supervised learning algorithms such as neural networks, support vector machines, and decision trees enable the modeling of intricate interdependencies within electronic circuits. Unsupervised learning techniques, including clustering and dimensionality reduction, facilitate efficient exploration of the design landscape by identifying patterns and correlations. Additionally, reinforcement learning algorithms offer an autonomous approach to circuit optimization through iterative learning and refinement. Real-world applications of machine learning-driven optimization in electronics and computer engineering span various domains, including power-efficient integrated circuits, signal processing algorithm optimization, and layout optimization for enhanced performance and reliability. Moreover, machine learning techniques play a crucial role in mitigating variability in semiconductor manufacturing processes, ensuring robustness and reliability of electronic systems in the face of uncertainties. Despite the promising potential of machine learning in circuit design optimization, challenges such as dataset acquisition, model interpretability, and scalability to complex circuits persist. Addressing these challenges requires innovative research endeavors, including the development of hybrid optimization techniques and novel hardware architectures.
DOI: https://doi.org/10.52783/tjjpt.v45.i02.6339
Un filósofo sin fronteras. Obituario de Ernesto Garzón Valdés (1927-2023)
Authors: De Lucas Javier
Published: May 2024

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L’otite esterna acuta: dalla diagnosi al trattamento
Authors: Lavezzo Giovanni , Pietrolati Gina , Iacono Alessandra , Marchetti Federico
Published: May 2024

Acute otitis externa (OEA) is an infectious of the external auditory canal with peak inci- dence between 5 and 9 years. Predisposing factors are the summer period, water sports and duct injuries (e.g. cotton buds). The diagnosis is clinical and the responsible agents are mainly bacteria (Pseudomonas aeruginosa followed by Staphylococcus aureus). The therapy involves the local use of acidifiers and/or antiseptics for mild forms while for moderate forms topical antibiotics (in monotherapy or in combination with cortisone and/or anaesthetics). The use of systemic antibiotics should be reserved only for severe forms or those not responsive to topical therapy.
Un dolore in sede parasternale: la sindrome di Tietze
Authors: Pecile Paolo
Published: May 2024

The author describes two cases of costochondritis (Tietze syndrome) detected within a short period of time in two 13-year-old girls.
Un "classico" caso di corea reumatica
Authors: Orsi Silvia Maria , Burrone Marco , Carrato Valentina , Consolaro Alessandro
Published: May 2024

The diagnosis of rheumatic chorea was ultimately made in a 10-year-old boy who had begun to experience difficulty in grasping objects and tying shoelaces. Subsequently, the performed echocardiography documented mild mitral insufficiency.
Se ha crisi e MaNGIE male pensa a mitocondiopatia
Authors: Gauci Maria Cristina , Di Nora Alessandra , Meli Concetta
Published: May 2024

The diagnosis of mitochondrial neurogastrointestinal encephalopathy (MNGIE) syndrome, using next-generation sequencing (NGS) panel for genes associated with encephalopathy, was finally made in a 4-year-old girl who presented with marked dystrophy (with diarrhoea, abdominal pain and dysphagia) and postural instability, along with subsequent epileptic seizures.
Influence of the integrity of the riparian zone on the Capão Comprido Stream Water Basin (DF) by simulating different spatial discretizations with the SWAT+ model
Authors: Nogueira Moíra Paranaguá , Da Silva Priscilla Regina , Minoti Ricardo Tezini
Published: May 2024

As zonas ripárias são áreas lindeiras aos corpos hídricos e prestam diversos serviços ambientais. Contudo, a utilização inapropriada desses espaços, com conversão para fins de expansão urbana e de fronteiras agrícolas, tem comprometido a sua integridade ecológica. O objetivo deste trabalho foi verificar uma nova perspectiva de análise da influência da integridade da zona ripária em bacias hidrográficas com base em diferentes possibilidades de discretização espacial e representação da paisagem, da fase terrestre do balanço hídrico, sob as perspectivas das unidades de paisagem disponíveis no modelo Soil and Water Assessment Tool (SWAT+). Como estudo de caso, definiu-se a bacia do córrego Capão Comprido, no Distrito Federal. Houve dificuldades na calibração e verificação do modelo com o uso do softwareSWAT Toolbox, com valores de Nash-Sutcliffe Efficiency (NSE) e de logaritimo (log)NSE abaixo de 0,5; percent bias (PBIAS) acima de ±15; e coeficiente de determinação (R2) abaixo de 0,6. Resultados esses que, embora melhores que a simulação inicial, são ainda insatisfatórios, conforme as métricas e valores adotados como referência. Contudo, constatou-se que a modelagem hidrológica de bacias hidrográficas por meio da determinação das unidades de paisagem, disponível no SWAT+, possui potencial para uma representação aprimorada das bacias hidrográficas, por diferenciar as características das partes mais elevadas do relevo (uplands) das partes mais baixas, a zona ripária (floodplains). As simulações confirmaram que o incremento das zonas ripárias contribuiu para a redução do escoamento superficial e da carga de sedimentos na bacia hidrográfica. Por outro lado, contribuiu para o aumento do escoamento subsuperficial, da percolação, do fluxo de retorno e da recarga de aquífero profundo.
Causal Associations of DNA Methylation and Cardiovascular Disease: A Two-Sample Mendelian Randomization Study
Authors: Gao Hui , Li Jiahai , Ma Qiaoli , Zhang Qinghui , Li Man , Hu Xiaoliang
Published: May 2024

Background: There is growing evidence that concentrations of DNA methylation are associated with cardiovascular disease; however, it is unclear whether this association reflects a causal relationship.
Methods: We utilized a two-sample Mendelian randomization (MR) approach to investigate whether DNA methylation can affect the risk of developing cardiovascular disease in human life. We primarily performed the inverse variance weighted (IVW) method to analyze the causal effect of DNA methylation on multiple cardiovascular diseases. Additionally, to ensure the robustness of our findings, we conducted several sensitivity analyses using alternative methodologies. These analysis methods included maximum likelihood, MR-Egger regression, weighted median method, and weighted model methods.
Results: Inverse variance weighted estimates suggested that an SD increase in DNA methylation Hannum age acceleration exposure increased the risk of cardiac arrhythmias (OR = 1.03, 95% CI 1.00–1.05, p = 0.0290) and atrial fibrillation (OR = 1.03, 95% CI 1.00–1.05, p = 0.0022). We also found that an SD increase in DNA methylation PhenoAge acceleration exposure increased the risk of heart failure (OR = 1.01, 95% CI 1.00–1.03, p = 0.0362). Exposure to DNA methylation-estimated granulocyte proportions was found to increase the risk of hypertension (OR = 1.00, 95% CI 1.00–1.0001, p = 0.0291). Exposure to DNA methylation-estimated plasminogen activator inhibitor-1 levels was found to increase the risk of heart failure (OR = 1.00, 95% CI 1.00–1.00, p = 0.0215).
Conclusion: This study reveals a causal relationship between DNA methylation and CVD. Exposed to high levels of DNA methylation Hannum age acceleration inhabitants with an increased risk of cardiac arrhythmias and atrial fibrillation. DNA methylation PhenoAge acceleration levels exposure levels were positively associated with the increased risk of developing heart failure. This has important implications for the prevention of cardiovascular diseases.
Hyperkinetic and Hypokinetic Movement Disorders in SSPE: A Systematic Review of Case Reports and Case Series
Authors: Garg Ravindra Kumar , Pandey Shweta , Malhotra Hardeep Singh , Jain Amita , Uniyal Ravi , Kumar Neeraj , Rizvi Imran
Published: May 2024

Background: Subacute Sclerosing Panencephalitis (SSPE) typically presents with periodic myoclonus; however, a spectrum of movement disorders including dystonia, chorea, tremor, and parkinsonism have also been described. This review aims to evaluate the array of movement disorders in SSPE, correlating them with neuroimaging findings, disease stages, and patient outcomes.
Methods: A comprehensive review of published case reports and case series was conducted on patients with SSPE exhibiting movement disorders other than periodic myoclonus. PRISMA guidelines were followed, and the protocol was registered with PROSPERO (2023 CRD42023434650). A comprehensive search of multiple databases yielded 37 reports detailing 39 patients. Dyken’s criteria were used for SSPE diagnosis, and the International Movement Disorders Society definitions were applied to categorize movement disorders.
Results: The majority of patients were male, with an average age of 13.8 years. Approximately, 80% lacked a reliable vaccination history, and 39% had prior measles infections. Dystonia was the most common movement disorder (49%), followed by parkinsonism and choreoathetosis. Rapid disease progression was noted in 64% of cases, with a disease duration of ≤6 months in 72%. Neuroimaging showed T2/FLAIR MR hyperintensities, primarily periventricular, with 26% affecting the basal ganglia/thalamus. Brain biopsies revealed inflammatory and neurodegenerative changes. Over half of the patients (56%) reached an akinetic mute state or died.
Conclusion: SSPE is associated with diverse movement disorders, predominantly hyperkinetic. The prevalence of dystonia suggests basal ganglia dysfunction.
The importance of accouting for microentrepreneurs: maximizing tax and strategic benefits
Authors: Oliveira Rosimeire , Sá Juliana , Severino Juliana
Published: May 2024

This article highlights the relevance of accounting for micro-entrepreneurs, demonstrating how effective accounting management can not only assist in strategic decision-making but also in maximizing available tax benefits. Through a detailed review of literature and legislation, the positive impacts that accounting can have on financial sustainability and the growth of micro-enterprises are explored, especially in the context of tax benefits offered to companies that maintain adequate accounting records. Although the Individual Microentrepreneur (MEI) in Brazil is not required to maintain accounting, it is highly recommended due to the associated advantages. This study explores the importance that accounting offers to micro-entrepreneurs as a tool to support business management, take advantage of legal deductions, and optimize tax burden. Using an exploratory approach through documentary and bibliographic research, data and information from public and private sources are analyzed. The results highlight accounting as a fundamental tool for business sustainability and success.
Job Design and Employee Involvement on SMEs Performance: The Mediating Role of Employee Motivation
Authors: Ohene Afriyie Emelia , Owusu-Acheampong Eugene , Opare Darko Lawrencia , Oduro-Nyarko Cynthia
Published: May 2024

The study used empirical data to explore the impact of job design and employee involvement on Small and Medium-Sized Enterprises (SMEs’) performance. Data was collected from 367 employees of Ghanaian SMEs using random sampling. IBM SPSS 24 and AMOS-SEM were used for confirmatory factor analysis and to analyse the latent variables. The measurement model was tested on the entire dataset using exploratory factor analysis. The investigation demonstrated a strong fit for a four-factor hypothesis model. The study revealed a statistically significant beneficial relationship between job design and employee involvement in organisational performance. It also found a favourable correlation between job design, employee involvement and motivation. However, there was a negative correlation between employee motivation and organisational performance. The study uniquely focused on SMEs in an emerging economy like Ghana using financial sector tiers two and three. The implication is that job design and employee involvement improve SMEs’ performance and give them a competitive advantage. The study underlines the significance of job design and employee involvement in Ghanaian SMEs, mainly in the Greater Accra Region. This study is of great value as it informs policymakers and actors of small and medium enterprises of the need to appropriately design jobs that interest and elicit employee involvement and performance.