bluuebunny/crossref_metadata_2025 huggingface dataset:
Overcoming Immune Depletion is the Main Goal of Developing New Therapies
Authors: Ricardo Gobato  , Abhijit Mitra
Published: December 2021

In recent years, immunotherapy has revolutionized the treatment of cancer; However, inflammatory reactions in healthy tissues often have side effects that can be serious and lead to permanent discontinuation of treatment. This toxicity is not yet well understood and is a major obstacle to the use of immunotherapy. When the immune system is so severely activated, the resulting inflammatory reaction can have detrimental effects and sometimes serious damage to healthy tissue. We wanted to know if there was a difference between an optimal immune response that aims to kill cancer and an unwanted response that could affect healthy tissue. Identifying the distinctive elements between these two immune responses allows the development of new, more effective and less toxic therapeutic approaches.

Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management
Identification of a Mimicry of the Protein that Potentially Isolates the Mutated p53 Material and Prevents Further Protein Accumulation
Authors: Ricardo Gobato  , Abhijit Mitra
Published: December 2021

The team first screened a set of protein mimics originally designed to target Alzheimer's disease and type 2 diabetes. The results identify a mimicry of the protein that potentially isolates the mutated p53 material and prevents further protein accumulation. The researchers then showed that segregation of mutated p53 grains by protein mimicking restored the suppressive function of the p53 tumor, leading to the death of a wide range of cancer cells. Importantly, protein mimicry therapy effectively reduces tumors that contain mutated p53 while showing no significant toxins for healthy tissue, resulting in significantly longer survival. "As the prevalence of cancer increases worldwide, there is an urgent need for new cancer therapies to complement or replace existing therapies," said the study's lead author. Here we show the first successful use of a small molecule amyloid inhibitor as an anticancer agent. We believe that this will have a far-reaching impact, as it effectively bridges the gap between amyloid disease and cancer and is the basis for passing on information approaches in the design of new and robust cancer mutation therapies for the p53 mutation.

Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management
THEORY, METHODOLOGY AND EVOLUTION OF THE CONCEPTS OF INNOVATIVE DEVELOPMENT OF THE MARKET ECONOMY
Authors:   International University of Innovative Technologies, Bishkek, Kyrgyz Republic, BIIMYRSAEVA E. M. , SUINALIEVA N. K. ,   International University of Innovative Technologies, Bishkek, Kyrgyz Republic, KHUSAINOVA E. Yu. ,   International University of Innovative Technologies, Bishkek, Kyrgyz Republic
Published: December 2021

This article includes the results of the authors' research on the theory, methodology and evo-lution of the concepts of an innovative economy in market conditions. innovation is based on the satisfaction of certain social needs, but at the same time, an increase in the efficiency of the use of individual resources or an increase in the efficiency of individual production units, or an increase in the efficiency of an enterprise as a whole as a result of the introduction of an innovation and receipt of an innovation does not always happen.
THEORETICAL BASIS OF FOOD SECURITY OF REGIONS IN ASPECT ECONOMIC SECURITY OF RUSSIA
Authors:   Moscow State Institute of International Relations of the Ministry of Foreign Affairs of Russia, Moscow, Russia, AKHMETZHANOVA L. R.
Published: December 2021

The article examines the food security of the regions in the aspect of the economic security of Russia. The theoretical approaches to food security of Russian authors and international organizations (FAO, World Bank) systematized. The levels and approaches to food security of the regions investigated in compar-ison with the international and national levels. The elements of food security at the country level identified in order to highlight the regional dimension. The factors (drivers) and their impact on the food system identified, which can be interpreted both at the national and regional levels, together making up a conceptual character-istic of the state's food security. The creation of a coordinated policy at the level of regions and the country as a whole is proposed.
UNCONVENTIONAL MONETARY POLICY AND A MODERN VIEW ON CASH ISSUES
Authors:   Moscow State Institute of International Relations of the Ministry of Foreign Affairs of Russia, Moscow, Russia, GOGICHAEV Ch. A.
Published: December 2021

In the aftermath of the 2008 global financial crisis, central banks in developed countries began to resort to unconventional monetary policy measures as interest rates approached zero. Such actions have led to the expansion of the balance sheets of central banks due to the abnormal growth of excess reserves. The article discusses the misconception that such an increase in the monetary base can directly affect the volume of money supply through the action of the money multiplier mechanism and the narrow credit channel of the transmission mechanism. The opinion disputed that non-traditional measures of monetary policy, pro-vided they are adequate, lead to an increase in inflationary risks in the economy. The work focuses on the lack of a close relationship between reserves, the level of lending and the money supply, and attempts made to assess the boundaries of the monetary policy methods under consideration.
RESEARCH OF THE ACTIVITY AND FINANCIAL STATE OF SMALL ENTERPRISES IN THE REGIONS OF THE KYRGYZ REPUBLIC IN MARKET CONDITIONS
Authors:   Jalal-Abad State University, Jalal-Abad, Kyrgyz Republic, ABDYKADYROV P. M.
Published: December 2021

This article includes the results of the author's research on the features of the functioning of small enterprises in the regions of the Kyrgyz Republic and the systematization of factors influencing their development. Today, in the difficult economic conditions of our state, the decisive factor in the development and future of each region is the processes of organizing regional small enterprises in various industries. Un-fortunately, the economic conditions of the Kyrgyz Republic are characterized by the following difficult factors: weak economy of small enterprises, institutional uncertainty, many risks, ineffective public administration, in-sufficient innovation and production, also insufficient technology, underdeveloped venture capital business, legal, legal and regulatory instability, insufficient activity Kyrgyz entrepreneurs in innovative activities, lack of full funding for research, competition and scientific works. In an era of competition and the beginning of the transition to the sixth technological mode, the organization and development of small enterprises at the re-gional level can solve many problems of the country's economy, because no state can cope with the situation without small business.
FEATURES OF DIGITALIZATION OF THE BANKING SECTOR OF THE RUSSIAN ECONOMY
Authors:   Moscow State Institute of International Relations of the Ministry of Foreign Affairs of Russia, Moscow, Russia, MAMEDOV M. A.
Published: December 2021

The article discusses the issues of digitalization of the banking sector of the Russian economy. Banks are actively introducing various innovative disruptive technologies into their activities. Innovative tech-nologies have a significant impact on both quantitative and structural changes in banks and changes in their offerings for the products and services provided. As a result, of the increase in digital literacy of the country's population, the face of the consumer of banking services is also changing. Digital transformation leads to the polarization of the banking sector of the economy and the introduction of new non-financial services and products provided by banks to their consumers. The largest banks, through the introduction of various inno-vative technologies, create ecosystems.
EFFECTIVE USE OF CONTROLLING TOOLS IN THE SYSTEM AND IN THE PROCESSES OF ECONOMIC SECURITY MANAGEMENT OF THE RUSSIAN FEDERATION
Authors:   Kazan State Energy University, Kazan, Russia, TAMAKCHI A. S. , KANTOROEVA G. K. ,   Kyrgyz State University, Bishkek, Kyrgyz Republic
Published: December 2021

In this article, the authors clarify that the economic security of the Russian Federation directly depends on the dynamics of socio-economic development of the subjects, and on the level of their economic security, therefore, it becomes objectively obvious the need to switch to the most advanced and effective tools for managing the economy and society at the meso-level. One of such progressive methodological and in-strumental approaches is controlling, which is a decision support system at various levels of management. To the greatest extent, controlling, as a set of management tools, is in demand by corporations. But it should be understood that the subjects of the state or, as in our case, the subjects of the federation are, in essence, quasi-corporations that have many corporate characteristics, which means that the experience of strategic corporate management can be implemented into the management and management of such entities to solve the most important tasks, including ensuring dynamically sustainable and economically secure development at the meso-level. The results of the activities carried out by the state external control bodies show that at the meso-level, i.e. at the level of the subjects of the federation, there are constant violations both in the disposal of budgetary funds, and in the exercise of authority in the field of disposal of federal and municipal property, and within the framework of strategic planning of territorial development.
ON THE METHODOLOGY OF FINANCIAL ANALYSIS AND OPTIMIZATION OF THE ACTIVITIES OF ECONOMIC ENTITIES OF KYRGYZSTAN IN THE NEW ECONOMIC CONDITIONS
Authors:   International University named after K. Sh. Toktomamatov, Jalal-Abad, Kyrgyz Republic, KAYIMOV N. A. , ABDYKADYROV P. M. ,   Jalal-Abad State University, Jalal-Abad, Kyrgyz Republic, KUBANYCHBEKOV E. K. ,   Jalal-Abad State University, Jalal-Abad, Kyrgyz Republic
Published: December 2021

This article describes the methodology for financial analysis and optimization of the activities of enterprises and organizations, as well as economic entities of the commercial direction of Kyrgyzstan. As examples, data from Frunze LLC, which is located in the Chui region of the Kyrgyz Republic, were taken. As you know, when calculations are carried out, indicators are determined that characterize the true state of the research subjects regarding the performance of the main function. At the same time, it becomes necessary to organize financial analysis and determine the main indicators of the study of the activities of economic entities.
ADAPTIVE METHODS OF OPTIMAL CONTROL, ANALYSIS OF PRODUCT COST AND DEPENDENCE ON THE PRODUCTION AND SALES OF PRODUCTS
Authors:   Jalal-Abad State University, Jalal-Abad, Kyrgyz Republic, KUBANYCHBEKOV E. K. , KAIYMOV N. A. ,   International University named after K. Sh. Toktomamatov, Jalal-Abad, Kyrgyz Republic
Published: December 2021

The article includes the results of the authors' research on the optimal management of the activities of agricultural formations in the regions of Kyrgyzstan in the new economic conditions. The traditional approach to solving forecasting problems, based on identifying statistical patterns and dependences of agri-cultural production on production factors, in a market economy and especially in a transitional period cannot be considered sufficient, since it does not take into account the behavior of business entities adequately to the ongoing processes. Ensuring sustainable economic growth is one of the main tasks of the macroeconomic policy of any state
ANALYSIS OF THE PROBLEMS OF EXISTING MECHANISMS TO STIMULATE FINANCING OF «GREEN» PROJECTS
Authors:   Moscow State Institute of International Relations of the Ministry of Foreign Affairs of Russia, Moscow, Russia, SAMIDOV A. M.
Published: December 2021

The article analyzes the problems of existing mechanisms to stimulate financing of «green» projects. Statistical data on financing of «green» projects in the world and in Russia presented. Criteria and standards for financing «green projects», financing problems in regions with different levels of socio-economic development, and so on are considered.
SATISFACTION WITH MARRIAGE AS A FACTOR IN IMPROVING THE PROFESSIONAL PERFORMANCE OF WORKING WOMEN
Authors:   Vladimir State University named after Alexander Grigoryevich and Nikolay Grigoryevich Stoletov, Vladimir, Russia, Akinina E. B.
Published: December 2021

The article describes the results of an empirical study of the relationship between satis-faction with marriage and the effectiveness of professional activity of working women. The data obtained in the course of the study can be used in the practical activities of psychologists at enterprises and organizations to improve the efficiency of professional activity, increase the productivity of individual and joint labor of women, optimize their emotional and mental state, which will affect the economic efficiency of the organization.
EVOLUTION OF APPROACHES TO ASSESSING OF THE EMPLOYMENT EFFECTIVENESS SERVICES IN RUSSIA
Authors:   Vladikavkaz scientific center of the Russian Academy of Sciences, Vladikavkaz, Russia, Dzhioev A. V.
Published: December 2021

Based on a wide range of works, the author considers the evolution of ideas about assessing the effectiveness of employment services in Russia in 1991–2019, as well as the transformation of the national project to promote employment in 2020–2021. Shown are both theoretical problems of assessing the effec-tiveness of the employment policy at the regional level, and the practical aspects of an active state employ-ment policy, including retraining of wide layers of the unemployed population and their further employment, as well as proactive retraining taking into account the needs of companies in the real sector of the economy.
SMALL AND MEDIUM BUSINESSES IN THE SYSTEM OF REGIONAL AND MUNICIPAL GOVERNANCE
Authors:   Vladimir State University named after Alexander Grigoryevich and Nikolay Grigoryevich Stoletov, Vladimir, Russia, Dmitriev Yu. A. , Mamedov S. N. ,   Vladimir State University named after Alexander Grigoryevich and Nikolay Grigoryevich Stoletov, Vladimir, Russia, Vilkov A. S. ,   Vladimir State University named after Alexander Grigoryevich and Nikolay Grigoryevich Stoletov, Vladimir, Russia
Published: December 2021

The article examines small and medium-sized businesses in the system of regional and mu-nicipal government. Particular attention is paid to entrepreneurship as one of the main factors in accelerating the pace of economic growth through innovative transformation of production. This type of activity is of partic-ular importance in ensuring sustainable development of the regional and municipal economy.
ORGANIZATION IN RUSSIA OF THE REHABILITATION PROCESS OF PERSONS WITH CEREBROVASCULAR DISEASES IN A REHABILITATION CENTER
Authors:   Vladimir State University named after Alexander Grigoryevich and Nikolai Grigoriev Stoletov, Vladimir, Russia, Usenkova E. V. , Kulakova P. S. ,   Rehabilitation center “Three Sisters”, Moscow, Russia
Published: December 2021

The article discusses the rehabilitation process of persons who have suffered from cerebro-vascular diseases, traumatic brain injuries, brain tumors within the framework of a multidisciplinary approach in a rehabilitation center. Emphasis is placed on the importance and timeliness of team work of specialists, setting goals, tasks for optimal improvement of the patient's quality of life and social adaptation.
MODERN CONCEPTS OF INTANGIBLE ASSETS’ VALUE CREATION
Authors:   Financial University under the Government of the Russian Federation, Moscow, Russia, Nurgalieva E. I.
Published: December 2021

The article analyzes modern concepts of intangible assets’ value creation: “Intangible value chain” by G. Ahonen and “Value creation mixer” by R. Normann and R. Ramirez. Based on the results of identifying the advantages and disadvantages of these concepts, the author's concept of value creation “Value creation funnel” is proposed.
ORGANIZATION OF PSYCHOLOGICAL AND PEDAGOGICAL SUPPORT OF PROFESSIONALIZATION OF COLLEGE STUDENTS
Authors:   Vladimir State University named after Alexander Grigoryevich and Nikolay Grigoryevich Stoletov, Vladimir, Russia, Filatov D. O. , Filatova O. V. ,   Vladimir State University named after Alexander Grigoryevich and Nikolay Grigoryevich Stoletov, Vladimir, Russia
Published: December 2021

The article is devoted to the problem of professional formation of the personality of a college student during the period of study. The theoretical analysis of scientific and practical literature on the research problem allowed the authors to determine the mental reliability of the individual as a determinant of profes-sional development during the period of college education. The article describes the program of psychological and pedagogical support of students.
CREATING CONDITIONS FOR THE FORMATION OF LIFE COMPETENCIES IN PRESCHOOL CHILDREN WITH MENTAL RETARDATION IN A PRESCHOOL EDUCATIONAL INSTITUTION
Authors:   Vladimir State University named after Alexander Grigoryevich and Nikolay Grigoryevich Stoletov, Vladimir, Russia, Ukhina N. A.
Published: December 2021

The article deals with the organization of the process of formation of life competencies in pre-schoolers with mental retardation in a preschool educational institution. The directions of correctional work in the conditions of interaction of kindergarten, parents, institutions of additional education are presented. The features of the development of life competencies in preschoolers with mental retardation are determined.
CONTINUING EDUCATION: PERSONAL QUALITIES OF OFFICE EMPLOYEES AS A FACTOR OF SUCCESS OF THE ORGANIZATION
Authors:   Vladimir State University named after Alexander Grigoryevich and Nikolay Grigoryevich Stoletov, Vladimir, Russia, Filatov V. O. , Savelev I. I. ,   Vladimir State University named after Alexander Grigoryevich and Nikolay Grigoryevich Stoletov, Vladimir, Russia
Published: December 2021

The article is devoted to the problem of compliance of personal qualities of employees of offices of multifunctional centers (MFC) with the requirements of professional activity. The conducted diagnostic study allowed the authors to develop and implement a program for the diagnosis and devel-opment of personal and emotional-volitional regulators of the psyche of MFC employees, which ensures the professional realization of employees. The methods used, the results of research and evaluation of the effectiveness of the psychological support program and the scope of their practical application are presented.
A FEATURES OF THE VALUE-MOTIVATIONAL SPHERE OF THE PERSONALITY OF TEACHERS OF A PRESCHOOL EDUCATIONAL ORGANIZATION
Authors:   Vladimir State University named after Alexander Grigoryevich and Nikolay Grigoryevich Stoletov, Vladimir, Russia, Shamanin N. V.
Published: December 2021

The article raises the question of the peculiarities of the value-motivational sphere of the indi-vidual in the context of her professional activity. An empirical study of the value-motivational sphere of the personality of teachers of preschool educational organizations has been carried out. It is suggested that the value-motivational sphere of the personality of preschool educational institutions has a number of features due to the specifics of professional activity.
DEVELOPMENT OF PUBLIC ADMINISTRATION QUALITY INDICATORS IN THE SPHERE OF NATIONAL SECURITY
Authors:   Russian Academy of National Economy and Public Service under the President of the Russian Federation, Moscow, Russia, Gordienko D. V.
Published: December 2021

In the context of the escalating struggle for leadership between the United States and China, the tasks of realizing its own interests, ensuring national security and improving the quality of public admin-istration are becoming especially urgent for Russia. The purpose of the article is to substantiate an approach to the development of indicators of the quality of public administration in the field of national security. The analysis of terminology and connectedness of syntactic constructions in strategic planning docu-ments, as well as prospects for the realization of the national interests of the Russian Federation in the context of economic relations between the countries of the strategic triangle Russia – China – USA is carried out. The results allowed us to propose a list of indicators of the quality of public administration for the implementation of national interests. The proposed approach to the development of indicators of the quality of public administration in the field of national security in the context of the intensification of the struggle for leadership between the United States and China makes it possible to significantly increase the level of information and analytical support and im-prove methods of state control and monitoring of relevant indicators of national security. The proposed approach can be used to substantiate recommendations to the leadership of our country to improve state control and monitoring of relevant indicators of national security.
STRATEGIC DEVELOPMENT OF THE AUTOMOTIVE INDUSTRY BASED ON PROMISING INNOVATIVE TECHNOLOGIES
Authors:   Samara National Research University, Samara, Russian Federation, Podbornova E. S.
Published: December 2021

Improving the efficiency of the automotive industry largely depends on the innovation activity of the region and the country as a whole. This implies the need to form a high-quality national innovation system. It should include large-scale R&D, fundamental and applied industry research with substantial finan-cial investments in the development and implementation of innovative technologies, and all activities in this area should be based on a competent innovation policy. Due to the current political instability, potential sanc-tions measures by the United States and the West, the unstable economic situation of business, due to re-strictions due to COVID-19 (lack of demand, large losses, insufficient resource base), such a system cannot be created only by the efforts of market structures. Thus, state participation in regulating the development and support of knowledge-intensive enterprises is relevant today.
The modeling of effective parameters on public bus passengers’ boarding time prediction
Authors:   Civil Engineering Department, Ondokuz Mayıs University, Samsun, Turkey, Aydın Metin Mutlu
Published: December 2021

Passengers’ boarding times at bus stops have a great importance to calculate dwell and travel time for scheduling process in public transport operations. However, there are not so much observed boarding times data in the actual bus transport systems and it may cause some prediction problems in scheduling process of public transport operations. For this reason, accurate estimation of the boarding times will ensure correct calculation of dwell and total travel time for bus transport systems. Based on this idea, this study aims to model boarding times of each passengers by evaluating different parameters using two different (statistical and optimization analysis) methods. For this purpose, a comprehensive data collection process was conducted in total seven different cities of Turkey based upon their population. Two new models were developed for boarding time estimation by evaluating various parameters using a multiple Ordinary Least Square (OLS) regression and Artificial Bee Colony (ABC) algorithm as statistical and optimization methods, respectively. Study results showed that modeling of boarding times by considering various parameters is an effective strategy to improve the performance of bus transport systems by using developed two models
Effect of Saw Type Corrugated Pipe on Laminar Convective Heat Transfer by Using SiC-Water Nanofluid: A Numerical Study
Authors:   Department of Mechanical and Manufacturing Engineering, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia, Rabby Md Insiat Islam , Hossain Farzad ,   Department of Mechanical and Production Engineering, Islamic University of Technology, Gazipur 1704, Bangladesh, M M Raihan ,   Department of Mechanical Engineering, University of Leeds, Leeds, United Kingdom ****Jamuna Gas, Dhaka 1212, Bangladesh, Piya Afrina Khan ,   Department of Mechanical Engineering, University of Leeds, Leeds, United Kingdom ****Jamuna Gas, Dhaka 1212, Bangladesh, Rhythm Riyazul Kabir ,   Jamuna Gas, Dhaka 1212, Bangladesh, Kamal M Mustafa ,   Bangladesh Army University of Engineering and Technology, Bagatipara, Qadirabad Cantoment, Natore 6431, Bangladesh
Published: December 2021

Enhancing the heat transfer rate is highly required to remove excessive heat load from the heat transfer apparatus, which may cause massive damage to the equipment. Thus, increment of heat transfer area is one of the prime solutions for this issue. The increment of heat transfer area can be done by enhancing the pipe wall and incorporating nanoparticles with working fluids because nanoparticles showed much faster heat dispersion due to a vast surface area for heat transfer and increased thermal conductivity. Also, small molecules of nanoparticles are allowed for free movement and thus micro-convection, promoting high thermal conductivity. Higher thermal conductivity is mainly the result of a higher heat transfer rate. Therefore, in this study, a saw-type corrugated tube was considered along with the SiC-water nanofluid as the working fluid to determine the improvement of laminar convective heat transfer in terms of the Nusselt number, heat transfer coefficient, and pressure loss. The result demonstrated that by increasing the Reynolds number, the Nusselt number, heat transfer coefficient, and pressure loss were increased significantly with the enhancement of SiC-water concentration. At a Reynolds number of 1200, the maximum increment of Nusselt number in comparison to the base fluid was 9.15% when the corrugated pipe was considered. Meanwhile, the maximum improvement of heat transfer coefficient for SiC-water nanofluid in comparison to the base fluid was 37.66%.
Earth fault detection in distributed power systems on the basis of artificial neural networks approach
Authors:   Department of Electrical Engineering, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran., Ahmadi Ali , Aghajari Ebrahim ,   Department of Electrical Engineering, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran., Zangeneh Mehdi ,   Department of Electrical Engineering, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran.
Published: December 2021

Nowadays, the advancement of microgrids promises numerous economic and environmental advantages of renewable energies to nations and societies. The presence of decentralized energy units, however, makes serious technical challenges; for instance, criteria and procedure of fault recognition and diagnosis in this condition is entirely changing. This article, therefore, proposed a novel accurate and fast technique based on Artificial Neural Networks (ANN) for earth fault detection. A sample distributed power system considered for the proposed technique and different earth faults applied to this system consist of one phase, two phases and three phases faults. Also, any alteration of current and voltage signals of all phases is investigated at the fault occurrence moment. Analysis of simulation results demonstrates how the proposed technique could make faster responses and improve the reliability of the distributed power system by more accurate fault recognition in comparison with the other traditional methods such as the Wavelet Transformation technique. The proposed technique is likely to enhance the growth of renewable energy sources usage by decreasing operational risk factors and fault recognition delays.
A Numerical Model with Finite Difference Schemes for Multi-Species Solute Transport in Porous Media
Authors:   Hasan Kalyoncu University, Faculty of engineering, Civil Engineering Department, Şahinbey, Gaziantep, Turkey, GHAREHBAGHI Amin
Published: December 2021

A precise forecast of contaminant and solute transport has an inevitable role in the management of water resources. In accordance with this purpose, in this paper, a novel one-dimensional numerical model for the transport of a decay chain through homogeneous porous media is proposed. To develop the suggested model, two different schemes of the finite difference method, namely the Lax-Wendroff scheme and Fourth-Order scheme, are used. The verification and validation of the established model are examined by the analytical results of three multi-species solute dispersion problems with three- and four-chain members. The total mean square error, L2- and L∞-norms are applied to assess the results. Although analyses show that both schemes provided reliable results, the numerical results of the Lax-Wendroff scheme are more accurate.
ПЕРСПЕКТИВНІ ТЕХНОЛОГІЇ БІОПАЛИВНОЇ ЕНЕРГЕТИКИ
Authors: Никируй Л.І.  , Замуруєва О.В.  , Федосов В.С.  , Урбан О.А.  , Захарчук Д.А.  , Федосов С.А.
Published: December 2021

У роботі проаналізовано публікації авторитетних світових науковців і з двох сусідніх держав – України та Польщі у галузі біопаливної енергетики, щоб знайти закономірності як розвитку цього напрямку у світі і кожній державі зокрема, так і визначити перспективи для спільних досліджень. Аналіз ґрунтується на результатах даних, опублікованих у міжнародних наукових базах даних Web of Science та Scopus. Виявлено стан розвитку галузі у кожній країні, проаналізовано як теоретичні, так і прикладні дослідження, спрямовані на практичне застосування.
ТЕОРЕТИЧНЕ ОБГРУНТУВАННЯ МОЖЛИВОСТІ ЗАСТОСУВАННЯ ТЕРМОКАТАЛІТИЧНОГО МЕТОДУ ДЛЯ ВИЗНАЧЕННЯ ТЕПЛОТИ ЗГОРЯННЯ ПРИРОДНОГО ГАЗУ
Authors: Шинкарук Х.М.  , Чеховський С.А.  , Піндус Н. М.  , Романів В.М.
Published: December 2021

Теоретично обґрунтовано можливість застосування термохімічного детектора для визначення теплоти згоряння природного газу. Встановлено, що ступінь згоряння горючих газів в термохімічних газоаналізаторах, заснованих на вимірі температури продуктів згоряння залежить, від об’єму і типу каталізатора, швидкості потоку аналізованого газу і концентрації в ньому горючих газів, а також від температури, що визначає необхідність для забезпечення більшою мірою згоряння горючих речовин підбору товщини шару каталізатора, його активності, температури і визначення допустимих концентрацій компонентів в газовому потоці. Використання імпульсного режиму роботи в газоаналізаторах з термокаталітичним перетворювачем дозволить забезпечити сталість об’ємної витрати аналізованого газу в детектор, що є вирішальним фактором забезпечення точності вимірювання теплового ефекту каталітичного згоряння; здійснювати процес каталітичного згоряння при малих концентраціях горючих компонентів в потоці газу-носія (повітря) за рахунок підбору об’єму проби, що вводиться в аналізатор, що може забезпечити стабільність властивостей каталізатора протягом тривалого часу.
ВПЛИВ ПАНДЕМІЇ КОРОНАВІРУСУ НА ВИРОБНИЦТВО ТА МЕДИЧНЕ ОБСЛУГОВУВАННЯ
Authors: Григор’єва Н.С., д.т.н., проф.  , Л.Гуменюк  , Марчук І. В.  , Д. Собчук  , Шабайкович В.А. д.т.н., проф.
Published: December 2021

Розглянуто заходи боротьби з пандемією коронавірусу при лікуванні захворювання коронавірусом, організації нормального функціонування виробництва та адаптації соціальної сфери обслуговування. Перший напрямок - основний, пов’язаний із заходами підготовки медичного персоналу, ліків, обладнання, оснащення, спеціалістів-лікарів, тестування, вакцинації. Досягається виключно при комплексному аналізі та синтезі рівня медицини, конструкції та  технології виробів, організації виготовлення, внутрішнього та зовнішнього середовища. Забезпечення нормального функціонування виробництва досягається шляхом його реорганізації, дезінфекції виробничих потужностей, використання автоматичного обладнання та оснащення, захист виробничого персоналу тощо. Зміни в соціальній сфері обслуговування включають її адаптацію до пандемії коронавірусу, реорганізацію транспортних потоків, послуг, заборони, обмеження та пристосованість до навколишнього середовища. Обов’язкове врахування причин пандемії коронавірусу.
ДОСЛІДЖЕННЯ ПРОЦЕСІВ ОБРОБКИ ДЕТАЛЕЙ ПРИ УДАРНО-ІМПУЛЬСНОМУ НАВАНТАЖЕННІ ВІБРОБУНКЕРА
Authors: В. Ю. Денисюк  , Симонюк В.П.  , Лапченко Ю.С  , Кайдик О.Л.  , Пташенчук В.В.
Published: December 2021

В статті представлені результати досліджень закономірностей циркуляційного вихрового руху робочого середовища та переміщення корпусу вібробункера при його симетричному ударно-імпульсному навантаженні. Встановлено, що ударно-імпульсні навантаження на вібробункер призводять до виникнення повільного циркуляційного руху робочого середовища, який інтенсифікується при несиметричному ударному навантаженні. Представлено результати експериментальних досліджень процесу вібраційної обробки деталей, перевірено відтворюваність експерименту та достовірність отриманих результатів. Здійснено аналіз технологічних можливостей віброобробки в широкому діапазоні частоти та розмаху коливань. Наочно представлено причини проблематичності вибору оптимальних режимів віброобробки та можливі напрямки їх подолання. Здійснено моделювання різних режимів роботи вібраційної установки. Аналіз результатів дав можливість виявити принципи оптимального підбору режимів віброобробки. Встановлено спосіб досягнення режиму роботи вібраційної установки з максимально ефективним використанням механічної енергії коливань.
Захарчук В.І., Захарчук О.В.,Галущак Д.О., Галущак О.О.
Authors: Захарчук В.І.  , Захарчук О.В.  , Галущак О.О.  , Галущак Д.О.
Published: December 2021

Відновлення деталей автомобілів та інших машин дозволяє використати їх матеріал, форму і залишкову довговічність, що зменшує потребу запасних частин, праці, енергії та матеріалів, а також сприяє збереженню навколишнього середовища. Дослідженнями встановлено, що 85% деталей машин стають не роботоздатними при зношуваннях поверхонь не більше 0,2-0,3 мм, а собівартість їх відновлення складає 50-60% від ціни нової деталі. Зношені поверхні можуть бути відновлені, як правило, декількома способами. В залежності від величини зношування, матеріалу деталі та її термообробки запропонований метод вибору раціональної технології відновлення зношеної поверхні в залежності від технологічних можливостей виробництва, умов експлуатації, собівартості відновлення, залежності вартості відновлення від довговічності роботи. Оцінка цих чинників виконується послідовно за технологічним, ресурсним та економічним критеріями. Остаточне рішення щодо вибору технології відновлення приймається на конкретному виробництві з врахуванням його технічних та фінансових можливостей.
Дослідження загроз від кібератак та захист персональної інформації.
Authors: Міскевич О.
Published: December 2021

У даній статті представлено основні групи для отримання кібердоступу до засобів обчислювальної техніки. Детально розглянуто безпосереднє, електромагнітне, аудіо та відео перехоплення. Досліджено куб кібербезпеки та недавні кібератаки а також безпеку інфраструктури Google для нашої персональної інформації.
LEGAL REGULATION OF THE STATE PERSONNEL POLICY IN THE FIELD OF HEALTH CARE IN UKRAINE
Authors: Malihon Yuliia Malihon Yuliia , Motailo Oleksii Motailo Oleksii , Avtomieienko Alla Avtomieienko Alla
Published: December 2021

The purpose of the article is to study the features of regulatory and legal regulation of state personnel policy in the field of health care in Ukraine.
The article determines that the formation of the legal framework for the effective functioning and development of state personnel policy of the health care system is a priority for improving the efficiency of the medical sector. The article analyzes scientific developments on improving the staffing of the health care system in Ukraine, in particular: articles of the Constitution of Ukraine, provisions of the Labor Code, articles of the Law of Ukraine "On Employment", articles of the Law of Ukraine "On Collective Bargaining", articles Law of Ukraine "On labor protection", provisions of the Law of Ukraine "On vacations", articles of the Law of Ukraine "On remuneration", provisions of the Law of Ukraine "Fundamentals of legislation of Ukraine on health care", provisions of the Law of Ukraine "On improving accessibility and quality of health care" in the countryside. " It is determined that the main source of labor law and state regulation of labor relations, regardless of the industry, is the Code of Labor Laws. The main elements (features) of the employment contract are studied, namely: individual-personal feature, organizational feature, material feature, regulatory feature, subject feature. The principles of state policy in the field of labor protection are determined. An analysis of the orders of the Ministry of Health for 2020-early 2021 on personnel policy in the field of health care, which confirmed the interest of the direct entity in the form of the Ministry of Health of Ukraine in the formation of regulatory framework for personnel policy of the health care system of Ukraine.
Keywords: health care system, normative-legal provision, laws, codes, personnel policy, state regulation.
MANAGEMENT OF UAV BORDER SURVEILLANCE AS TECHNOLOGICAL AND SOCIAL CONSEQUENCE OF ANTI-PANDEMIC PROGRAMS
Authors: Jaroslav Jevčák Jaroslav Jevčák , Martin Kelemen Martin Kelemen
Published: December 2021

Tackling the complex problem of illegal migration and the external security of the European Union's borders is an ongoing challenge. On the one hand, there are security and anti-social aspects, and on the other hand, there are also health and safety aspects, which are currently gaining in intensity and importance in pandemics. The professional community is therefore looking for effective tools and procedures to manage these risks and challenges. The aim of the article is to identify the research space for solving the topic in the agenda of the European Union and to identify initial knowledge from the own pre-research of the use of UAV (Unmanned Aerial Vehicle) border surveillance within anti-pandemic programs as a technological and social consequence of pandemic, as pre-research notes of authors.
Keywords: management, unmanned aerial vehicle, safety and security, pandemics.
ILLEGAL EXPORT-IMPORT OPERATIONS AS AN OBJECT OF RESEARCH IN THE SCIENTIFIC WORKS OF RESEARCHERS
Authors: Yuriy Krutik Yuriy Krutik
Published: December 2021

The article provides a bibliometric analysis of publications on the queries of "illegal import operations" and illegal export operations during 1984-2021. Emphasis was placed on Scopus as it is the largest bibliographic database in the world, representing over 21,000 international scientific publishing houses. The work is devoted to the study of the application of bibliographic analysis as a quantitative approach in assessing the documentary and informational workflow, which makes it possible to carry out a formalized analysis of the results of scientific activity quite accurately. The main results demonstrate an increase the topic interest of illegal export-import operations in different social and economic areas and in different countries. The analysis of publications proves the lack of a literature review on the topic with the keywords illegal import operations and illegal export operations. It has also been found that bibliometric analysis is an effective tool that can be used for literature reviews across all branches of the social and economic sciences.
The results obtained in this study provide additional information on the development of the topic of illegal export-import operations, sources of publications, and their dynamics, as well as justification for the development of a literature review as an obligatory part of scientific articles on the topic under study.
Keywords: bibliometric analysis; Scopus database; illegal import transactions; illegal export transactions.
THE GROUNDBREAKING PUBLIC GOVERNANCE OF NATIONAL SECURITY WITHIN THE CONDITIONS OF GEOPOLITICAL THREATS
Authors: Victoriia Zagurska-Antoniuk Victoriia Zagurska-Antoniuk , Olha Rudenko Olha Rudenko , Mateusz Piskorski Mateusz Piskorski
Published: December 2021

Ensuring public administration of national security is currently gaining extreme significance as seen from the perspective of geopolitical transformations. The addressed issue is particularly relevant and calls for a thorough and systematic research, in view of the global economic crisis, the fight against the COVID-19 pandemic and the global geopolitical transformations and threats that have swept over the world during the recent decade.
Despite the sound regulatory framework for public administration in the field of national security and the existing mechanisms of state regulation therein, the effectiveness of public administration in protecting national interests and ensuring the security of individuals, society and the state from external and internal threats requires further enquiry. That said, public administration of national security encompasses the mechanisms to ensure the safeguarding of vital interests of man and citizen, society and the state, and accordingly the sustainable development of society, prompt detection, prevention and neutralization of real and potential threats to national interests.
Key words: geopolitical security, geopolitical threats, public administration, national security, social security, COVID-19.
LEADERSHIP APPROACH FOR DECENTRALIZATION AND ADMINISTRATIVE-TERRITORIAL REFORM
Authors: Igor Koziura Igor Koziura , Victoriia Koltun Victoriia Koltun
Published: December 2021

The article summarizes Canada’s experience in carrying out measures aimed at reforming the local government system by optimizing the administrative and territorial structure. The fundamental principles of preparation and implementation of the administrative-territorial structure reform are clarified. They consist in the use of positive and proactive leadership, transparency, openness, timely informing on changes and application of the practice of broad consultations in the activities of local self-government bodies. Ways to adapt foreign experience in organizing activities aimed at reforming the administrative-territorial structure in Ukraine are offered.
Keywords: local self-government, leadership, decentralization, administrative and territorial reform.
IMPERATIVES OF THE DIGITAL ECONOMY DEVELOPMENT IN UKRAINE
Authors: Tetiana Halimon Tetiana Halimon
Published: December 2021

The priority vector of development of many countries of the world is digital transformation and creation of a hypercompetitive digital economy. The key trend of modern global economic development in all countries of the world is the rapid spread of information and communication, digital technologies and the development of the digital economy, which causes changes in the business environment, transaction methods and the level of connections between individual entities. The digital economy is an innovative dynamic economy based on the active introduction of innovations and information and communication technologies in all types of economic activities and spheres of society, which increases the efficiency and competitiveness of individual companies, the national economy and living standards. In the third wave of globalization, the digital economy plays an important role in the development of countries, the most important factor of which is information and knowledge, as well as ways to access them. Increasingly, the digital economy is intertwined with the traditional economy, making clear demarcations increasingly difficult. The main products of the digital economy are the same goods and services of the traditional economy provided by computer equipment and digital systems such as the global Internet. However, the rapid development of digitalization is becoming a source not only of new opportunities, but also of serious threats and problems for all segments of the population that need to be taken into account. That is, the digitalization of the economy and all spheres of public life, on the one hand, becomes a challenge and threat to established business models and successful strategies of behavior of enterprises in a market economy, on the other - opens new opportunities for improvement and competitive advantage. Digitalization has significant benefits for economic development. Benefits at the level of the whole society include: economic and social effect of digital technologies for business and society; improving the quality of life; increasing the productivity of all social labor; the emergence of new models and forms of business that can increase profitability and competitiveness; increasing the transparency of economic transactions and ensuring the possibility of their monitoring. Key words: digital economy, innovative activity, innovative development, competitiveness, scientific and technological progress, information and communication technologies, information society.
CURRENT ASPECTS OF LAND RELATIONS IN UKRAINE
Authors: Olena Mykhailovska Olena Mykhailovska , Olga Kokhan Olga Kokhan , Wojciech Slomka Wojciech Slomka
Published: December 2021

The article examines the current components of land relations in Ukraine. Land legal relations are public land relations that arise in the field of interaction of society with the environment and are governed by the rules of land and agricultural law. The importance of using the potential of sustainable development is emphasized. It is established that land management (a set of socio-economic and environmental measures) is an important tool for regulating land relations. The main factors of reducing soil fertility and their depletion are identified. The relationship between the agricultural sector, society and the environment is presented.
The connection between different levels of public management on the way to sustainable development of the agricultural sector is outlined. The main directions of formation of effective land relations are characterized. It is stated that an effective system of land management is a real mechanism for resolving pressing issues and bringing agricultural land tenure and land use to an orderly state.
Keywords: land relations, sustainable development, land management, potential.
TRANSFORMATION OF THE SOCIAL FUNCTION OF THE STATE: CONCEPTUAL APPROACHES
Authors: Iryna Kolosovska Iryna Kolosovska , Radosław Zagórski Radosław Zagórski
Published: December 2021

This article conceptualizes modern approaches to the transformation of the social function of the state in the context of the influence of globalization processes, the ambiguity of the formation of the socio-cultural context, the actualization of the latest risks and threats associated with the spread of the COVID-19 pandemic. We accentuate the inconsistencies and contradictions between the declared social priorities and the inefficiency of the management mechanisms of their practical implementation. The article substantiates the priority directions of the regulatory role of the state in the context of social risk management, formation of social security, adherence to the principle of social justice, and harmonization of interests of representatives of various social groups.
Key words: public administration, state, social functions, governance mechanisms, globalization, social risks, COVID-19 pandemic, social justice.