bluuebunny/crossref_metadata_2025 huggingface dataset:
Rethink photographic narratives: historiographical insights into Magnum Photos and the legacy of Sergio Larraín
Authors: Brandt Jean Paul
Published: January 2024

Photography, as a medium, has long been recognized for its unparalleled ability to capture and convey stories, with Magnum Photos standing as a testament to the profound influence of visual narratives on shaping global perceptions and historical interpretations. This essay delves deeply into the historiographical intricacies of Magnum and the enduring legacy of Sergio Larraín. It underscores the delicate interplay between objective documentation and the inevitable subjective interpretation that often accompanies powerful imagery. Larraín's distinct humanistic approach, which prioritized the intricate subtleties of human experiences amidst broader socio-political landscapes, frequently found itself juxtaposed, if not overshadowed, by Magnum's commercial and editorial imperatives. Such reframing not only alters the essence of the captured moment but also raises critical questions about the ethics of photojournalism and the overarching responsibilities of influential photographic agencies. In today's digital age, where the rapid dissemination of images can lead to widespread reinterpretation, the imperative for a more ethically grounded and transparent approach to photojournalism becomes even more pronounced. Through this exploration, the essay underscores the transformative power of photographs, emphasizing the importance of preserving the sanctity of the original vision while also acknowledging and respecting the myriad interpretations that such images can evoke.
On Sommersian Concept Analysis
Authors: Castro-Manzano Martín
Published: January 2024

In this contribution we explore in what sense Sommers’ tree theory, a novel philosophical tool, could be useful for Formal Concept Analysis. Basically, we argue that Sommers’ theory is instrumental for the latter insofar as it helps avoid category mistakes. To reach this goal we start by recalling the basic notions of Formal Concept Analysis, then we provide a primer on Sommers’ tree theory and, finally, we informally explore what we call Sommersian Concept Analysis.
Treatment options for oropharyngeal carcinoma — An umbrella review
Authors: Plutecki Dawid , Szczepanek Elżbieta , Szczepanek Małgorzata , Nasser Ameen , Hajdyła Paweł , Wrona Paweł
Published: January 2024

Introduction: Our umbrella review aimed to summarize and revisit the evidence from all of the meta-analyses and systematic reviews regarding the treatments of oropharyngeal squamous cell carci-noma (OPSCC). Materials and Methods: Major medical databases such as PubMed, Scopus, Embase, Web of Science, Google Scholar, Cochrane Library, BIOSIS, and EBSCO were searched. The overall search process was conducted in 3 stages. Results: Finally, a total of 28 studies met the inclusion criteria and were included in this study. Out of those 28 meta-analyses, a total of 315 primary studies were screened in order to extract the data and perform the statistical analysis. In total, data from 22,619 patients was analyzed. Conclusion: The main objective of the present umbrella review was to summarize and analyze all of the evidence-based data provided by numerous meta-analyses and systematic reviews regarding the treatment of OPSCC. Our study delivers the most up-to-date and evidence-based results regarding the different therapeutic modalities of this malignancy in one concise review, making it the ultimate tool for physicians treating OPSCC.
Anatomical features of the mandibular canal and their clinical significance — review of literature
Authors: Skrzat Janusz , Ryniewicz Wojciech , Goncerz Grzegorz , Kozerska Magdalena
Published: January 2024

The clinical issues related to the anatomical variation of the mandibular canal have been extensively analyzed since the 19th century. Evolving dentistry techniques and advancements in the prosthetics forced to collect detailed information about anatomical variations of the mandibular canal due to its neurovascular content. Therefore, its radiographic imaging became an essential part of the oral surgery, in order to avoid complications resulted from an accidental damage of the mandibular canal.
Recepcja twórczości Virginii Woolf w międzywojennej prasie w Polsce
Authors: Pająk Paulina , Cybulska Kamila
Published: January 2024

Artykuł ukazuje szeroką recepcję twórczości Virginii Woolf w międzywojennej prasie w Polsce. Na podstawie ponad stu materiałów prasowych, omówiono wybrane tytuły prasowe i mediatorów kulturowych, którzy odegrali kluczową rolę w tym procesie, przyczyniając się do transferu modernizmu i rozwoju kultury czytelniczej. Artykuł analizuje odmienne strategie interpretacji i transferu kulturowego rozwijane pod wpływem centrów kulturowych i transnarodowych sieci modernistycznych.
Miejsce kultury w programach Jerzego Giedroycia
Authors: Hofman Iwona
Published: January 2024

Celem artykułu jest próba określenia znaczenia pub-licystyki kulturalnej i literatury w realizacji programów politycznych wypracowanych w kręgu „Kultury”. Miesięcznik ukazywał się w latach 1947–2000 nakła-dem Instytutu Literackiego w Paryżu, którego redak-torem był Jerzy Giedroyc. Z analizy 637 numerów „Kultury” wynika, że 65% materiałów informacyjnych i publicystycznych o tematyce wschodniej i zachodniej poświęcone jest kulturze i historii, odpowiednio 1174 publikacji związanych z Ukrainą, Litwą, Białorusią i 663 — z Niemcami.
Early administration of canine parvovirus monoclonal antibody prevented mortality after experimental challenge
Authors: Larson Laurie , Miller Lindy , Margiasso Mary , Piontkowski Michael , Tremblay Danielle , Dykstra Stephanie , Miller Jennifer , Slagter Barton J. , Champ Debbie , Keil Daniel , Patel Mayur , Wasmoen Terri
Published: January 2024

OBJECTIVE

To evaluate the effectiveness of canine parvovirus monoclonal antibody (CPMA) as a treatment against canine parvovirus (CPV-2)–induced mortality and to support USDA product licensure.

ANIMALS

28 purpose-bred Beagle dogs aged 8 weeks were randomized to the treated (n = 21) or control (7) group.

METHODS

Dogs were challenged intranasally with 104.2 TCID50 virulent CPV-2b on Day 0 and monitored for 14 days for fecal viral shed and clinical disease. All dogs began shedding CPV-2 on Day 4 and were treated intravenously with a single dose of either CPMA (0.2 mL/kg) or saline (equal volume). No additional treatments were given to either group. Feces and sera were collected for quantitative analysis of fecal viral shed (hemagglutination) and antibody responses (hemagglutination inhibition and dot-blot ELISA), respectively. Dogs were monitored twice daily for parameters including lymphopenia, fever, vomiting, abnormal feces, inappetence, and lethargy. Humane endpoints triggered euthanasia by a veterinarian masked to treatment groups. The primary outcome variable was prevention of mortality as compared to controls.

RESULTS

Mortality was prevented in all CPMA-treated dogs compared to 57% mortality in the control group (P = .0017, Fisher exact test). Canine parvovirus monoclonal antibody–treated dogs also experienced less severe and/or shorter durations of diarrhea, fever, vomiting, CPV-2 shedding in feces, and lymphopenia. Both groups showed similar immunoglobulin M responses as measured by semiquantitative analysis.

CLINICAL RELEVANCE

Intravenous administration of CPMA can effectively improve clinical outcome when administered early in CPV-2 disease. Canine parvovirus monoclonal antibody treatment after proven infection does not interfere with adaptive immunity.
A One Health perspective on the use of genotypic methods for antimicrobial resistance prediction
Authors: Maddock Kelli J. , Burbick Claire R. , Cole Stephen D. , Daniels Joshua B. , LeCuyer Tessa E. , Li Xian-Zhi , Loy John Dustin , Sanchez Susan , Stenger Brianna L. S. , Diaz-Campos Dubraska
Published: January 2024

Antimicrobial resistance is a global One Health concern with critical implications for the health of humans, animals, and the environment. Phenotypic methods of bacterial culture and antimicrobial susceptibility testing remain the gold standards for the detection of antimicrobial resistance and appropriate patient care; however, genotypic-based methods, such as PCR, whole genome sequencing, and metagenomic sequencing, for detection of genes conferring antimicrobial resistance are increasingly available without inclusion of appropriate standards for quality or interpretation. Misleading test results may lead to inappropriate antimicrobial treatment and, in turn, poor patient outcomes and the potential for increased incidence of antimicrobial resistance. This article explores the current landscape of clinical and methodological aspects of antimicrobial susceptibility testing and genotypic antimicrobial resistance test methods. Additionally, it describes the limitations associated with employing genotypic-based test methods in the management of veterinary patients from a One Health perspective. The companion Currents in One Health by Maddock et al, AJVR, March 2024, addresses current and future needs for veterinary antimicrobial resistance research.
Authors: Irianti Tatang , Yasmin Intan Farida , Astuti Ratih Dwi , Purnomo Hari
Published: January 2024

Tumbuhan mengandung metabolit sekunder, termasuk flavonoid, yang molekulnya masih terikat pada glikosida atau bukan molekul bebas. Perlakuan hidrolisis membentuk molekul bebas pada penelitian ini diharapkan dapat meningkatkan aktivitas antioksidan. Uji aktivitas antioksidan menggunakan uji penangkal radikal 2,2-difenil-1-pikrilhidrazil (DPPH). Nilai Inhibitory Concentration 50% (IC50) yang diperoleh akan menunjukkan aktivitas antioksidan dari hidrolisis asam fraksi air daun duwet (Syzigium cumini L.) dan hidrolisis asam fraksi tidak larut heksana daun nangka (Artocarpus heterophyllus). Hasil hidrolisis fraksi air daun duwet dan fraksi tidak larut heksana daun nangka diukur aktivitas antioksidannya dengan uji penangkal radikal DPPH menggunakan spektrofotometer UV-Vis. Untuk mengidentifikasi senyawa dalam fraksi air dan fraksi tidak larut heksana yang berperan sebagai antioksidan, dilakukan analisis kualitatif dengan KLT dan penentuan total senyawa fenolik dan flavonoid. Aktivitas antioksidan daun duwet tertinggi terdapat pada fraksi air terhidrolisis selama 3 jam, sedangkan daun nangka pada fraksi tidak larut heksana terhidrolisis selama 3 jam. Dengan demikian, hidrolisis yang dilakukan pada penelitian ini mampu meningkatkan aktivitas antioksidan.
Potensi Liposom Sebagai Nanocarrier Antituberkulosis Pada Sediaan Inhalasi
Authors: Parameswari Natashya , . Sriwidodo
Published: January 2024

Tuberkulosis (TB) merupakan penyakit infeksi saluran pernapasan yang masih menjadi masalah kesehatan global hingga saat ini. Terdapat lebih dari 10,6 juta kasus TB dengan angka kematian sekitar 1,4 juta pada tahun 2021. Regimen terapi oral yang terdiri dari isoniazid (INH), etambutol (EMB), pirazinamid (PZA) dan rifampisin (PZA) walaupun memiliki angka keberhasilan pengobatan hingga 95%, banyaknya limitasi terapeutik berkontribusi pada tingkat kepatuhan pengobatan yang rendah dan perkembangan strain Mtb yang resisten terhadap OAT. Salah satu strategi pengobatan dalam rangka mengatasi limitasi terapi yang telah ada adalah perubahan rute penghantaran obat melalui inhalasi. Nanocarrier berbasis liposom telah terbukti efektif dalam meningkatkan bioavailabilitas obat serta menurunkan toksisitas terapi. Oleh karena itu tinjauan artikel ini bertujuan untuk mengeksplor potensi liposom sebagai nanocarrier pada sediaan inhalasi.
A Needs Assessment for a Local Social Policy Data Sharing Program
Authors: Sibbald Shannon L. , Sedigb Kimia , Graham Ross J. , Haji Simoni , Chhatwal Prabhnoor , Lizotte Dan , Bhatti Jasminder
Published: January 2024

Planners seek collaborative and diverse strategies to address complex challenges across Canada. In the Region of Waterloo, local governments and stakeholders adopted The Waterloo Region Community Data Program (WRCDP), a social policy data-sharing system for information on economic and social development. This study examined the needs of Community Data Program (CDP) users to investigate whether CDPs are utilized effectively. We considered how optimal use of CDP data may advance planning to resolve structural and behavioral challenges in municipalities. We surveyed 17 participants from the WRCDP to assess needs of organizational members regarding accessing data, data analysis, and networking. Participants expressed enthusiasm for the CDP’s potential but lacked training in accessing and analyzing available data. A limitation of this study is small participant sample size and how results may not be generalizable to other locations. Organizational members remained optimistic about the system’s potential for planning and policy when provided with the necessary support.
Dislexia: las estrategias de afrontamiento y el rendimiento académico en estudiantes entre 9 y 12 años en instituciones educativas de la ciudad de Armenia
Authors: Cuellar Calvo Stiven , Gallego Echeverry Mónica
Published: January 2024

Los estudiantes con dislexia enfrentan situaciones de estrés que los llevan a utilizar estrategias de afrontamiento para asumir los retos que implican la dificultad en el aprendizaje de la lectoescritura. El objetivo de esta investigación fue establecer la posible relación entre las estrategias de afrontamiento y el rendimiento académico en estudiantes con dislexia en instituciones educativas de la ciudad Armenia. La muestra fue no probabilística de 62 estudiantes entre 9 y 12 años de edad, con un enfoque cuantitativo y diseño correlacional. Se utilizó la escala de afrontamiento para niños, un tamizaje de dislexia y los boletines académicos de los estudiantes. No se encontró correlación significativa entre las variables de estudio; sin embargo, se concluye que los estudiantes con dislexia sí utilizan estrategias de afrontamiento y que existen otros factores predeterminantes que pueden estar impactando en el rendimiento académico.
Diplomacia de la defensa colombiana
Authors: Vargas Eider Yovanny
Published: January 2024

El concepto de diplomacia de defensa se construyó en la Revisión Estratégica de Defensa Inglesa. A través de este concepto, el Reino Unido generó influencia de su política de defensa para lograr sus propios objetivos en la política exterior. Varios Estados han introducido el concepto en su política exterior para mejorar la prevención de conflictos y de situaciones de crisis mediante el empleo “no violento” de los recursos y capacidades militares. Este artículo se propone explorar cómo Colombia desarrolló e hizo evolucionar el concepto en su propia política exterior. Se empleó el método Process Tracing para identificar las inferencias causales del concepto en el caso colombiano. Se utilizó un enfoque teórico ecléctico, tomando las aproximaciones teóricas acordes al desarrollo y evolución del concepto de forma holística. Se concluye que el concepto ha sido desarrollado para un ambiente simétrico.
Categorizaciones del terrorismo y la violencia de la extrema derecha estadounidense y europea
Authors: Ortiz-Arellano Edgar
Published: January 2024

El terrorismo aqueja a la sociedad global por la violencia y daños que provoca en las poblaciones, así como a la estabilidad de los gobiernos. A partir del siglo XXI, grupos e individuos de extrema derecha optaron por la vía violenta y la actividad terrorista como estrategia de operación, de ahí que el objetivo de este artículo fue el análisis del terrorismo en su forma actual, con especial énfasis en su relación con los movimientos de extrema derecha surgidos en los Estados Unidos de América y Europa. Con base en la literatura especializada y de los datos cuantitativos se llegó a la conclusión de que los hechos terroristas han disminuido en general, sin embargo, los incidentes violentos por parte de la extrema derecha radicalizada van en aumento de manera consistente.
Importancia de una Ley de ciberseguridad y ciberdefensa para Colombia
Authors: Guzmán-Pacheco Julián Antonio
Published: January 2024

El artículo busca reflejar la importancia de la aprobación de una Ley de Ciberseguridad y Ciberdefensa para Colombia a través de un análisis reflexivo, teniendo en cuenta sus características y perspectivas tanto nacionales como internacionales. Este se realizó a partir de una metodología cualitativa, donde a través de la revisión de la literatura existente se logró comprender el fenómeno de investigación. De esta manera, se lograron descubrir los elementos constitutivos que requieren una ley de ciberseguridad y ciberdefensa desde su relevancia y aporte para la inteligencia nacional. Por último, se lograron identificar las dificultades legales con las cuales opera actualmente la Ciberseguridad y Ciberdefensa en Colombia, desde su inadecuada interpretación y ajuste de las leyes existentes, precisamente como factor clave y estratégico del desarrollo que coincide con la aparición del fenómeno web, cuya expansión ha generado la quinta dimensión de las guerras modernas, afectando la cotidianidad de los diferentes actores.
Sintomas depressivos e ansiosos na equipe de enfermagem durante a pandemia da COVID-19: revisão sistemática
Authors: Inácio Antônio Sávio , Vilar Aldo Ferreira Castello Branco , Osis Sibila Lilian , Tavares Leonardo Machado
Published: January 2024

Objetivo: Analisar a prevalência de sintomas de ansiedade e depressão em profissionais de enfermagem durante o atendimento a pacientes com COVID-19. Método: revisão sistemática, conforme recomendações do PRISMA, com delimitação baseada na estratificação de componentes PICO. Busca realizada nas bases de dados da Pubmed, LILACS, Scielo e BVS e WHO-COVID-19, com estudos originais transversais, durante o período de janeiro de 2020 a janeiro de 2022. Os estudos selecionados tiveram sua qualidade metodológica avaliada por meio do Joanna Briggs Institute Checklist for Analytical Cross Sectional Studies. Os achados foram verificados por meio de distribuições de frequências simples das variáveis analisadas. Resultados: Foram identificados 1.500 estudos através das estratégias de busca, destes 22 foram incluídos por meio dos critérios de elegibilidade. A pandemia de COVID-19 desencadeou um enorme impacto na saúde mental dos profissionais de enfermagem, sobretudo mulheres, com idade igual ou superior a 30 anos, casadas, enfermeiras, jornada laboral maior que 30 horas semanais, com menos de 10 anos de efetiva atuação profissional e com vínculo público. Conclusão: A presente revisão sistemática encontrou elevados níveis de sintomas ansiosos e depressivos na equipe de enfermagem durante a pandemia da COVID-19. Esse dado aponta para a necessidade de criação de estratégias de cuidado da saúde mental desta população.
How Florida’s Courts Should Evaluate the Admissibility of Field Sobriety Testing and Blood THC Levels Evidence in Marijuana Impaired Driving Prosecutions
Authors: Bomhoff Christopher
Published: January 2024

Field sobriety and blood alcohol concentration tests are proven reliable techniques to determine whether a person us under the influence of alcohol. No such technique has been developed to reliably determine whether a person is under the influence of marijuana. However, despite a lack of scientific consensus regarding the reliability of field sobriety and blood toxicology tests to determine marijuana impairment, these methods are routinely used as evidence of guilt in marijuana impaired driving prosecutions. Twenty-four states have legalized the recreational use of marijuana, and Florida appears to be set to join them in the near future. As a result of increased access to marijuana, it is logical to assume that the percentage of car accidents involving drivers suspected of marijuana impairment will rise. This comment evaluates the current state of science’s ability to detect marijuana impairment; how different states where recreational marijuana use is legal have addressed the admissibility of field sobriety and blood toxicology tests under the Daubert expert evidence admissibility principles in marijuana impaired driving prosecutions; and recommends that Florida judges exclude such evidence from marijuana impaired driving prosecutions until the underlying science is proven to be reliable.
Analisis Rantai Pasok, Margin dan Efisiensi Saluran Pemasaran Beras di Kabupaten Bone
Authors: Hasrullah Excelsia Ramadhany , Munizu Musran , Fudjaja Letty , Hasrullah Hasrullah
Published: January 2024

This study aims to identify and examine the pattern or mechanism as well as the role of the rice supply chain in Bone District and to analyze the size of the margin and the efficiency of the rice marketing channel in Bone District. This research took place in four districts, namely Awampone District, Sibulue District, Barebbo District and Bengo District, Bone Regency which is one of the potential food crop production centers. The method used in this study is a qualitative analysis approach and quantitative analysis. Respondents were 30 farmers, marketing agency informants in the study consisted of 4 milling informants and 5 trader informants. Target supply chain patterns, the role of supply chain actors, marketing margins and marketing efficiency are the main discussions in this study. The conclusion in this study is that there are five actors in the supply chain process in Bone Regency, namely farmers, millers, collector traders, retailers and inter-island retailers. The results of the analysis of rice marketing in Bone Regency show that there are three types of marketing channels, namely: marketing channel I, direct farmers to consumers. Marketing channel II, from farmers to collectors (milling) then to retailers, then to consumers. Marketing channel III, from farmers to collectors (milling) then to inter-island retailers, then to consumers. marketing channel margin I does not exist, marketing channel II margin is IDR 6,800/kg, and marketing channel III margin is IDR 9,300/kg. And the existing marketing channels in Bone Regency have been efficient for farmers.
Sikap Petani Padi Terhadap Program Pupuk Bersubsidi di Desa Caturharjo Kecamatan Pandak Kabupaten Bantul
Authors: Triyono Triyono , Rifa’i Afrizal
Published: January 2024

The subsidized fertilizer program is a distribution program implemented by the government to help farmers meet farmers' fertilizer needs in rice cultivation. This study aims to, describe the profile of rice farmers, describe the attitude of rice farmers towards the subsidized fertilizer program, describe the factors that correlate with the attitude of farmers to the subsidized fertilizer program. The method used in this study used descriptive analysis. Data collection was carried out by direct interviews with farmers using questionnaire guides. The results showed that the average age of rice farmers in Caturharjo Village had an age range of 56-65 years, and the average education taken at the elementary school level. Rice farmers in Caturharjo Village have experience in farming with a range of 36-50 years, the average area of farmer's arable land is 1,463.33 m2, with the status of ownership of arable land, namely rent. The net income of rice farmers in one planting season is Rp1,000,000-3,000,000, and the number of family members is 3-4 people. The attitude of rice farmers towards the subsidized fertilizer program is included in the good category. Factors correlated with farmers' attitudes to subsidized fertilizer programs. The value of the correlation coefficient was very weak in the variables age (-0.011), education level (0.015), and land area (-0.245) with farmers' attitudes towards subsidized fertilizer programs, while for experience variables (-0.157) had a weak relationship strength with farmers' attitudes towards subsidized fertilizer programs.
Polityka rodzinna – różnorodność form wsparcia rodzin
Authors: Kampka Franciszek
Published: January 2024

Artykuł podejmuje problematykę wyzwań stojących przez polityką rodzinną i omawia różnorodne formy i strategie tej polityki. Polityka rodzinna zajmuje się rodziną jako podstawową instytucją społeczną. Polityka rodzinna w badaniach społecznych może być perspektywą, poprzez którą analizowane są działania rządu i konsekwencje tych działań dla rodzin. Może być opisywana poprzez zakładane cele i kierunki działań, struktury, w ramach których jest realizowana, funkcje, jakie wypełnia, czy procesy zmian, jakie inicjuje. W rozważaniach na temat polityki rodzinnej uwzględnić należy działania, które są bezpośrednio adresowane do rodzin, jak i te, które wpływają na ich kondycję pośrednio. W ramach bezpośrednich działań wyróżnić można: 1) prawa i działania dotyczące składu rodziny (kwestie małżeństwa, rozwodów, adopcji, urodzin, opieki zastępczej), 2) wsparcie ekonomicznego dla rodzin, 3) rozwoju dzieci (zdolności rodziców do pielęgnowania, wychowania i kształcenia dzieci), 4) opieka (zwłaszcza w odniesieniu do chorych lub niepełnosprawnych członków rodziny), 5) relacje, trwałość i stabilność rodzin. Namysł nad polityką rodzinną wiąże się z koniecznością odpowiedzi na zasadnicze pytania. Czy ma ona służyć utrzymaniu status quo, czy prowadzić do zmiany sytuacji? Czy ma realizować strategię leczenia czy zapobiegania?
Ways of experiencing motherhood of a child with disability
Authors: Myśliwczyk Iwona
Published: January 2024

Macierzyństwo to zjawisko oczywiste i naturalne, które z reguły utożsamiane jest z wyjątkowymi doświadczeniami matek i pozytywnym postrzeganiem społecznym. Wyjątek może stanowić pełnienie roli matki dziecka z niepełnosprawnością. Wówczas macierzyństwo nabiera innych znaczeń, a sposoby doświadczania roli matki nie są już tak oczywiste, jak w przypadku dziecka pełnosprawnego. 

Celem artykułu jest zaprezentowanie wyników badań rekonstrukcji przeżyć i interpretacji doświadczeń na temat macierzyństwa z dzieckiem z niepełnosprawnością oraz zaproponowanie możliwości wsparcia matek wychowujących dziecko z niepełnosprawnością.  Przedstawione w opracowaniu badania zostały osadzone w paradygmacie interpretatywnym, co w konsekwencji pozwoliło zastosować metodę biograficzną z wykorzystaniem autobiograficznego wywiadu narracyjnego.

Kwestia macierzyństwa z dzieckiem z niepełnosprawnością pojawia się w dyskursie publicznym i naukowym dość często, jednak perspektywa biograficzna odsłania indywidualne sensy nadane macierzyństwu. Rekonstruowana przez matki rzeczywistość jest złożona i składa z negatywnych emocji będących skutkiem zagrożenia, niepewności, dezorientacji i braku kontroli nad sytuacją wywołaną niepełnosprawnością dziecka. Obok nich w życiu kobiet sytuują się pozytywne emocje wynikające z akceptacji niepełnosprawności, najmniejszych efektów dziecka, czy poczucia spełnienia w roli matki. Subiektywna interpretacja doświadczeń przeżywanych przez matki wychowujące dziecko z niepełnosprawnością ukazuje niepowtarzalne biografie i dowodzi, że matki na wiele sposobów doświadczają tego macierzyństwa: macierzyństwo osamotnione, obciążone ryzykiem czy zdominowane niepełnosprawnością, ale także znormalizowane, wspierane i spełnione. Opowiedzianym historiom maki nadają własne znaczenia, które z ich perspektywy są istotne.
Psychoedukacja rodziców w przeciwdziałaniu transmisji pokoleniowej przemocy w rodzinie
Authors: Komorowska-Pudło Marta
Published: January 2024

Przemoc wobec dzieci w rodzinie to problem obserwowany przez stulecia. Jednym ze źródeł traktowania jej jako powszechnego, a przez wielu jako naturalnego sposobu wychowania, jest przekaz międzypokoleniowy. Obserwowanie w dzieciństwie przemocowych zachowań rodziców i naśladowanie ich w dorosłości wiąże się ze zjawiskiem transmisji międzypokoleniowej takich form relacji rodzinnych. W badaniach zaprezentowanych w artykule potwierdzono wysokie prawdopodobieństwo takiej transmisji. Dorośli małżonkowie doświadczający w dzieciństwie przemocy od własnych rodziców częściej niż nie doświadczający jej kierowali do swoich partnerów deprecjację oraz agresją fizyczną i werbalną. Rzadziej okazywali im swoje wsparcie i zaangażowanie w budowanie relacji. W badaniach ukazano także, że osoby doświadczające przemocy w dzieciństwie w wyniku uczestnictwa w zajęciach psychoedukacyjnych Szkoła dla Rodziców w pewnym stopniu zmieniły swoje postawy rodzicielskie z nieprawidłowych na prawidłowe. Zaczęły przejawiać wobec dzieci więcej akceptacji i zrozumienia ich prawa do rozwoju autonomii, stały się też bardziej konsekwentne i rzadziej stawiały wobec nich nadmierne wymagania. Badania potwierdziły, że istnieje możliwość osłabienia, a nawet zatrzymania procesu transmisji międzypokoleniowej przemocy wobec dzieci poprzez psychoedukacyjną formę wsparcia rodziny.
Marriage preparation, pastoral accompaniment, and relationship quality among migrant and intercultural couples in the Netherlands
Authors: Biemans Ward
Published: January 2024

This quantitative survey among migrant and intercultural couples in the Netherlands investigates the relationships between marriage preparation, pastoral accompaniment and relationship quality. Relationship quality may be negatively influenced by a process of cultural transition, by instability of the relationship itself or by underdeveloped communication skills between partners. Participants (n=223) have been married in the Catholic Church between 1995 and 2021. Correlations between various religious and spiritual activities and relationship quality have been calculated through linear regression analysis. Results show that overall, migrant couples and intercultural couples appreciate a more intensive, professional, and welcoming Marriage and Relationship Education (MRE) and pastoral accompaniment after marriage. It is also concluded that seeking reconciliation after a conflict (r=0.361) and experiencing forgiveness from one's spouse (r=0.188) are significantly associated with a higher perceived relationship quality. Finally, data indicate that migrants with a non-Western cultural background show a significant pattern of cultural defence (μ=-0,375) in comparison to Dutch people.
Family Support and Dietary Adherence in Individuals with Type 2 Diabetes Mellitus in Banten, Indonesia
Authors: Ridwan Ramadhanty Khoirunnisa Salim , Dewi Agil Dhiemitra Aulia
Published: January 2024

The aim of this study was to determine the correlation between family support and dietary compliance in diabetes patients. This observational, crossectional study was conducted among 92 Type 2 Diabetes Mellitus (T2DM) patients age 20–70 years in Citangkil Public Health Center, Cilegon, Banten, Indonesia. Data were collected using self administered questionnaire to measure the dietary adherence and family support. Data was analyzed using Fisher Exact Test. Among 92 respondents that participated in the study, 84 (91.30%) reported having good family support, while 8 (8.70%) reported having inadequate family support. Family support associated with dietary adherence in individuals with T2DM (p<0.05) in the Citangkil I Public Health Center area, Cilegon I, Banten, Indonesia. Good family support is expectedto increase dietary adherence in T2DM patients.
Nutrition Management for Acute Stroke with Right-Sided Hemiparesis: A Case Study
Authors: Md Said Norfarhana , Mohd Fahmi Teng Nur Islami , Mohamed Denil Nurnajwa , Rahim Hazelin Abdul
Published: January 2024

This case study aims to report on the nutrition management of acute stroke with right-sided hemiparesis using an approach of early enteral feeding intervention to prevent malnutrition. Mr. R, a 77-year-old Malay man was admitted to the hospital due to an acute stroke with right hemiparesis with underlying disease of Atrial Fibrillation (AF), hypertension, type 2 Diabetes Mellitus (DM), Chronic Kidney Disease (CKD) stage 3b, and significant Peripheral Artery Disease (PAD). His BMI was 24kg/m2 with a weight of 67kg and height of 1.67m, and he was presented with abnormal blood results. All his vital signs were normal, and he appeared lethargic. The patient was on bolus Nasogastric (NG) feeding via Ryle’s tube with polymeric formula. Inadequate enteral nutrition infusion related to infusion volume not yet reached, as evidenced by a 47% energy and 60% protein adequacy feeding history. The polymeric formula was changed to a diabetic-specific formula for better blood sugar control, and feeding was given according to the patient's needs. Mr. R required at least 70% of 1,675 kcal of energy and 53.6 g of protein (0.8 g/kg body weight) to prevent malnutrition. The patient was still on Ryle’s tube feeding and already achieved the targeted energy and protein requirements. Before being discharged, the patient was allowed orally, and a sample menu was given as guidance to avoid weight loss and muscle wasting during longterm recovery. This case highlights the importance of early enteral feeding support in stroke recovery and the need to prioritize meeting nutritional needs in stroke patient care. Mr. R showed improvement in health and nutrition and concluded that early and focused enteral nutrition support can lead to improved results and better quality of life for stroke survivors.
Impact of Nutritional Intervention for Patient with Cerebrovascular Accident and Atrial Fibrillation Secondary to Hypertensive Emergency
Authors: Roslan Noor Izati , Ahmad Zamuri Aina Nadhra , Ab. Hamid Mohd Ramadan , Binti Baharudin Nurul Nurliana
Published: January 2024

This case study aims to report on the nutrition management of Cerebrovascular Accidents (CVA) which have a higher risk of malnutrition due to dysphagia, hemiparesis, decreased mobility, and dementia. Mrs. L, a 76-year-old Chinese lady, was less responsive at home. Upon admission, she was diagnosed with hypertensive emergency complicated by CVA, newly diagnosed atrial fibrillation, and End-Stage Renal Disease (ESRD). Her Body Mass Index (BMI) is 22.5 kg/m2, which is underweight for her age. The patient, with abnormal blood results, high blood pressure, and poor Glasgow Coma Scale (GCS) score, was treated with nasogastric enteral feeding and a disease-specific formula for diabetes. Inadequate enteral nutrition infusion related to feeding has yet to optimize as evidenced by intake of 57% of energy and 0.6 g/kg body weight of protein. Mrs. L required 1,442 kcal of energy and 57.7 g of protein (1 g/kg body weight) to meet adequate bodily function and prevent further weight loss. The nasogastric enteral feeding was optimized to 250 mL, seven times daily using the same diabetic formula. Throughout follow ups, although the patient’s dietary intake improved, she experienced episodes of diarrhea. She was also put on a 500 mL fluid restriction per day. Considering those issues, the diseasespecific formula was changed to renal disease formula. The patient then progressed to a soft diet with improved GCS scores and other conditions. This case highlights dysphagia which is the leading cause of malnutrition in stroke patients, associated with poor prognosis, increased mortality, and deteriorated health outcomes, necessitating enteral nutrition support to enhance nutritional status and promote health. It can be concluded that MNT in managing patients with CVA, hypertensive emergency, and underlying diseases of diabetes and ESRD helps to improve the patient’s recovery. The patient's treatment and diet should be optimally adjusted through close monitoring and evaluation
Association between Sleep, Stress and BMI with Chrononutrition Behaviors among Military Personnel in Malaysia
Authors: Mohd Suki Ain Suhana , Zaman Mazuin Kamarul
Published: January 2024

This study aimed to find the association between sleep quality, stress level, and Body Mass Index (BMI) with the chrononutrition behaviors of military personnel. Six chrononutrition behaviors were assessed using the Chrononutrition Profile Questionnaire (CPQ). Sleep quality was measured by the Pittsburgh Sleep Quality Index (PSQI) and perceived stress using the Perceived Stress Scale (PSS-10). The associations between chrononutrition behaviors and sleep quality, stress level, and BMI were determined using the Fisher exact test. Data was collected from 210 participants (median age: 27.5 years). Most military personnel, 62% (n=129) experienced moderate stress. Approximately 59.2% (n=122) demonstrated poor sleep quality. Out of six chrononutrition behaviors, sleep quality was significantly associated with evening eating (p=0.004) and night eating (p=0.028). Stress level was significantly associated with evening eating (p=0.051), night eating (p=0.019), and eating window (p=0.014). No association was found between chrononutrition behaviors and BMI of military personnel. Chrononutrition behaviors are associated with sleep quality and stress level but not body mass index in military personnel. Further understanding of sleep quality and stress among military personnel is imminent to prevent future weight issues concerning altered eating behaviors in this population.
Dietetics Students' Perceived Facilitators and Barriers to Clinical Training in Malaysia: A Qualitative Theory-Guided Analysis
Authors: Eshamuddin Nur Amirah Nabihah , Hao Lim Jun , Ying Chin Yi
Published: January 2024

This study explored barriers and facilitators experienced by Malaysian dietetics graduates during clinical training in local healthcare settings. A qualitative study with phenomenological design was conducted on fifteen purposely selected fresh dietetics graduates, with a mean age of 24.7±0.8 years from seven local universities. Virtual interviews were conducted via the Cisco Webex and were verbatim transcribed and thematically analyzed using NVivo 12 Plus software. Data collection continued until data saturation was reached. Nine Theoretical Domain Frameworks (TDF-derived domains), comprising of 1) knowledge, 2) skills; 3) belief about capabilities; 4) intention; 5) goals; 6) memory, attention, and decision process; 7) environmental context and resources; 8) social influences; and 9) emotions domains, was utilized to develop open-ended questions in the semi-structured questionnaire. Within these domains, frequently associated sub-themes of perceived facilitators were identified: early preparation and comprehension. Pre-clinical classes that involve solving diverse and challenging cases equip students with practical understanding of clinical training. Curriculum-based university clinics offer valuable insights into hospital dietetics practice. Resources availability is crucial for effective Nutrition Care Process (NCP) implementation and aids in evidence-based nutrition counseling. Conversely, the factor that hinders clinical training reported by dietetics graduates is a lack of knowledge and readiness, particularly concerning their perceived knowledge before clinical training. Dissatisfaction also arises from challenges in building rapport, gathering patient information during counseling, and difficulties in assessing dietary recall with patients from diverse cultural backgrounds, affecting their readiness for dietetics practice and therefore, highlighting the need to enhance multicultural knowledge and cultural competency training among dietetics students. The findings from this study may assist in developing strategies to promote impactful experiences and enhance dietetic students' preparedness for clinical practice.
Stressing the gut-brain axis
Authors: Blank Niklas , Schneider Kai Markus , Thaiss Christoph
Published: January 2024

It is widely known that psychological stress influences many aspects of our health. This is particularly true in the case of inflammatory bowel disease (IBD), a widespread disease of the gut. We found that psychological stress leads to inflammation of the gut by changing the gut-residing nervous system, which may inform therapeutic approaches in the future.
Pengembangan Instrumen Kompetensi Profesional Guru Matematika Terintegrasi Nilai-Nilai Pendidikan Islam Berbasis Abad 21
Authors: Giantara Febri , Hitami Munzir , Risnawati Risnawati
Published: January 2024

The 21st century requires teachers to be able to have professional competence and also master IT. Mastering IT without being accompanied by the values of Islamic Religious Education will result in the birth of a generation that is intellectual but far from religious teachings. This will certainly cause a lot of damage on Earth later. To overcome this, it is necessary to develop an instrument that is able to measure the professional competence of high school mathematics teachers integrated with Islamic Religious Education values based on the 21st century. This ADDIE model is combined with the Andromeda Spiral Integration model. The sample of this study was 210 students at public high schools in Tapung District, Kampar Regency. The data analysis used was using EFA and CFA analysis which was analyzed with the SPSS 21 application. The development results showed that the instrument was successfully developed and met the validity, reliability and practicality for the development of an instrument. This study also succeeded in finding an integration model for the instrument developed which was named Spiral Andromeda Factor Analysis (SAAF).
What Religion Can Be
Authors: Freiberger Oliver
Published: January 2024

This article highlights some important conclusions in Karénina Kollmar-Paulenz’s study, “Lamas and Shamans,” and offers some reflections on its relevance for the study of religion more broadly. It argues that comparing the Tibetan/Mongolian process of creating a classification system for religion(s) with the parallel and analogous process in “Western” discourses can yield important insights, especially for the endeavor of category formation, which is crucial in Religious Studies.
From the History of Religions in Asia to a Global History of Religion
Authors: Kleine Christoph
Published: January 2024

This article examines the relationship between two contemporary perspectives on conceptualizing a global history of religion. The first is anchored in an entangled conceptual history, reconstructing the genealogy of “religion” back to the colonial nineteenth century. The second favours a multicentred perspective in studying knowledge systems and general concepts independent of the West and predating global modernity. By analysing Japanese religious history, the article illustrates both the potential for and the necessity of integrating these two approaches.
From Dharma to Sound
Authors: Lorea Carola
Published: January 2024

This piece takes as a starting point a close reading of Karénina Kollmar-Paulenz’s work and connects it to ongoing debates intersecting the fields of religious studies, the anthropology of religion, sensory studies, Global South studies and decolonial theory. It argues that attention to the layered history of local language categories that articulate religious difference constitutes a form of intellectual labour towards epistemic justice.
Decolonizing Concepts before It Was Cool
Authors: Mostowlansky Till
Published: January 2024

In her work on “Lamas and Shamans,” Karénina Kollmar-Paulenz takes a broad aim at the role of non-European knowledge in the humanities and social sciences. In this commentary, I take up some lines of inquiry that structure her argument, discussing them in the broader contexts of research on global history and continuing attempts to assess the status of categories deriving from non-European intellectual traditions.
Chasing new targets to fight antimicrobial resistance: identification of small molecules affecting the interaction of human hemoglobin with the IsdB hemophore of Staphylococcus aureus
Authors: Cozzi Monica , Failla Maria Cristina , Gianquinto Eleonora , Kovachka Sandra , Buoli Comani Valeria , Compari Carlotta , De Bei Omar , Giaccari Roberta , Marchesani Francesco , Marchetti Marialaura , Ronda Luca , Rolando Barbara , Baroni Massimo , Cruciani Gabriele , Campanini Barbara , Bettati Stefano , Faggiano Serena , Lazzarato Loretta , Spyrakis Francesca
Published: January 2024

Human hemoglobin (Hb) is the preferred iron source of Staphylococcus aureus. This pathogenic bacterium exploits a sophisticated protein machinery called Iron-regulated surface determinant (Isd) system to bind Hb, extract and internalize heme and finally degrade it to complete iron acquisition. IsdB, the surface exposed Hb receptor, is a proven virulence factor of S. aureus and the inhibition of its interaction with Hb can be pursued as a strategy to develop new classes of antimicrobials. To identify small molecules able to disrupt IsdB:Hb protein-protein interactions (PPIs), we carried out a structure-based virtual screening campaign and developed an ad-hoc immunoassay to screen the retrieved set of commercially available compounds. Saturation-transfer difference (STD) NMR was applied to verify specific interactions of a sub-set of molecules, chosen based on their efficacy in reducing the amount of Hb bound to IsdB. Among molecules for which direct binding was verified, the best hit was submitted to ITC analysis to measure the binding affinity to Hb, which was found to be in the sub-micromolar range. The results demonstrate the viability of the proposed in silico/in vitro experimental pipeline to discover and test IsdB:Hb PPI inhibitors. The identified lead compound will be the starting point for future SAR and molecule optimization campaigns.
Molecular Driving Force of a Small Molecule-Induced Protein Disorder-Order Transition
Authors: Mendoza-Martinez Cesar , Gupta Arun , Llabrés Salomé , Barlow Paul , Michel Julien
Published: January 2024

The selectivity and affinity of numerous protein-protein interactions is tuned via binding mechanisms that involve folding of intrinsically disordered regions (IDRs) on complexation. Yet there are currently no guiding principles for a similar molecular recognition strategy aimed at the design of small-molecule modulators of protein-protein interactions. Herein, the molecular driving forces that underpin selective ordering of the N-terminal intrinsically disordered ‘lid’ region of the oncoprotein MDM2 by the small molecule AM-7209 were elucidated by a combination of molecular dynamics simulations, calorimetry and NMR measurements. Strikingly, mutations of lid residues distant from the ligand-binding site modulate potency by up to three orders of magnitude. A key requirement for conversion of this IDR into an ordered motif is hydrophobic collapse via formation of a network of non-polar contacts between a chlorophenyl moiety of AM-7209 and the lid residue I19. Our findings underscore the crucial role protein IDRs can play in drug-resistance mechanisms and expand strategies available to medicinal chemists for ligand optimisation endeavours.
Stacked-ring aromaticity from the viewpoint of the effective number of π-electrons
Authors: Sugimori Ryota , Okada Kenji , Kishi Ryohei , Kitagawa Yasutaka
Published: January 2024

We theoretically examined the effective number of π-electrons in the closely π-stacked 4nπ electron dimers exhibiting stacked-ring aromaticity. Multi-configurational calculations for cyclobutadiene π-dimer models revealed that a double-triplet [1(T1T1)] character bearing 2 x (4n–2)π conjugated electrons + 4 formally unpaired electrons appears in the ground state at small stacking distances. Energy stabilization of the closely π-stacked dimers can be attributed to mixing intermolecular charge-transfer (CT) configurations. However, its energy gain would be insufficient for self-aggregation of the π-dimers with a stacking distance of ~3 Å.