bluuebunny/crossref_metadata_2025 huggingface dataset:
Análisis paleosismológico de la falla Acequión mediante perfiles topográficos de escarpa (Precordillera de San Juan, Argentina)
Authors: Colavitto Bruno , Alcacer Juan Manuel , Rothis Martín , Haro Federico , Blanc Pablo A. , Onorato Romina , Perucca Laura
Published: October 2021

Este trabajo se concentra en el extremo sur de la depresión Matagusanos-Maradona-Acequión entre la Precordillera Central y Oriental en la provincia de San Juan, Argentina. Se analizó una escarpa de falla asociada a la actividad cuaternaria de la falla inversa Acequión, de vergencia oriental. La misma muestra una longitud de aproximadamente 12 km con rumbo norte y un resalto vertical de hasta ~12 m en algunos sectores. Tras un análisis geomorfológico con control de campo se la pudo clasificar como una escarpa flexural con crestas de presión con retrocabalgamientos. A partir de modelos digitales de elevación de 5 m de píxel, se levantaron 70 perfiles topográficos transversales a la estructura y se estudiaron estadísticamente los quiebres de pendiente que presenta la escarpa y los valores de desplazamiento vertical de la superficie. Considerando el tipo de escarpa estudiado, estos últimos parecieran brindar mejor información. En función de los resultados obtenidos es probable que hasta 4 o 5 eventos de Mw mínima de 6.5-7.1 hayan ocurrido en la falla Acequión durante los últimos ~35 ka. Estos valores se aproximan a los obtenidos previamente por otros autores, aunque trabajos futuros de paleosismología de mayor detalle podrán confirmar la consistencia de la metodología aplicada. Adicionalmente, se realizó un levantamiento gravimétrico en el sector sur. La interpretación geofísica-geológica de la carta de anomalías residuales gravimétricas obtenidas, permitió definir la continuidad en subsuelo de al menos dos fallas de rumbo norte, sin evidencias de ruptura superficial. Estas estructuras pueden estar asociadas en profundidad a la falla Acequión y también estarían segmentando la bajada pedemontana oriental de la Precordillera Central.
Deformación cuaternaria en el piedemonte mendocino (32º 50´ S), Argentina
Authors: Moreiras Stella M. , Toural Dapoza Rafael , Junquera Torrado Sebastián , Gomez Laura , Euillades Pablo , Lenzano Luis
Published: October 2021

El piedemonte mendocino (32º 50´S) se localiza en el frente orogénico activo de los Andes, donde se concentra la mayor deformación cuaternaria del país. En particular, esta región presenta condiciones únicas para los estudios neotectónicos de sismicidad de intraplaca. Esta región se ubica dentro del segmento de Flat Slab pampeano y se asocia a la subducción de la Dorsal de Juan Fernández lo que originan la ausencia de vulcanismo en este segmento. Además, tectónicamente, este sector refleja un cambio en el estilo de deformación donde aflora en particular la unidad morfoestructural de la Precordillera Sur que culmina a esta latitud. En este segmento, el frente orogénico activo se asocia a fallas inversas N-S que afectan niveles aluviales pleistocenos tardíos. En función de sus parámetros morfométricos, se han estimado las magnitudes máximas de los sismos posibles y diferentes índices morfométricos que han permitido establecer los sectores de mayor deformación validados con métodos indirectos complementarios de interferometría mediante imágenes radar (técnica DINSAR). Este trabajo resume todos los estudios realizados hasta el momento para comprender el estilo de deformación activa cuaternaria que presenta el piedemonte mendocino.
Análise cienciomátrica das pesquisas sobre overtourism através do software iramuteq
Authors: Maracajá Kettrin Farias Bem , Pereira Luciana Melo , Pinheiro Isabelle De Fátima Silva
Published: October 2021

A presente pesquisa realizou uma análise cienciométrica de publicações sobre turismo em periódicos científicos, com o objetivo de evidenciar os trabalhos desenvolvidos sobre overtourism através do software qualitativo IRAMUTEQ de forma a possibilitar os drivers dos estudos sobre a temática, bem como, as principais correntes de autores internacionais da atualidade relacionadas ao tema. É uma pesquisa de cunho quantitativo, feita através dos resumos dos trabalhos sobre overtourism. A partir das bases de dados e da análise dos resumos dos artigos, foram selecionados aqueles que tiveram alguma influência da concepção dos algoritmos usados pelo software estatístico R. Os resultados da pesquisa mostram que o estudo sobre overtourism é atual e vem sendo trabalhado desde 2017, sendo levantados 137 artigos internacionais. Após a análise dos resumos dos principais trabalhos, através da nuvem de palavras, conteúdo e lexicometria, importantes direcionamentos foram traçados de modo que exista um melhor entendimento sobre a temática. Assim, foi possível afirmar que o termo overtourism remete a variáveis negativas provocadas ou intensificadas pelo turismo nos espaços prejudicando principalmente os moradores locais. Como limitação da pesquisa é importante destacar que existem poucos trabalhos sobre esse assunto e a escolha do idioma como sendo o inglês ocasionou exclusão de alguns artigos relacionados à temática.
ANÁLISE BIBLIOMÉTRICA DAS PUBLICAÇÕES QUE ASSOCIAM OS TEMAS INOVAÇÃO, GESTÃO E MODELO DE NEGÓCIO
Authors: Lessa Ester Onofre Barbosa , Gonzalez Inayara Valéria Defreitas Pedroso
Published: October 2021

O processo de inovar representa uma das formas de renovação das organizações quando acompanhado pela gestão e pelo tema modelo de negócio associado aos objetivos estratégicos. Por tal contexto, objetivou-se com este estudo identificar e analisar as principais publicações que integram os temas inovação, gestão e modelo de negócio. Para isto, foi realizada uma pesquisa bibliométrica por meio do método Proknow-C e utilizadas as bases de dados Scopus e Web of Science. Os resultados revelam que o Reino Unido se apresenta com o maior número de publicações que associam esses temas e que as publicações dos últimos dois anos equivalem a 50% dos estudos identificados, o que revela o crescente interesse nesse foco de investigação. Destaca-se a relevância da gestão na inovação do modelo de negócio, bem como outros fatores internos e externos que podem facilitar o processo de inovar.
BİR YER OLARAK GÖBEKLİ TEPE’NİN ÖTEKİLEŞ(TİRİL)EN SON SAKİNLERİ
Authors: KERVANKIRAN İsmail , KURNAZ Zeynep , BAŞÇI Elif
Published: October 2021

Dünyanın en eski inanç merkezi olan Göbekli Tepe’nin keşfi sonrasında mekânsal olarak yeniden üretilmesi, bir taraftan Göbekli Tepe’yi popüler hale getirirken, diğer taraftan Göbekli Tepe’ye kutsal bir yer olarak saygı duyan insanların bu yerle olan bağlarının kopması suretiyle yerel halkı “öteki”leştirmiştir. Ötekileş(tiril)en yerel halkın atalarından miras kalan inancın, ritüellerin ve kültürün kesintiye uğraması, hatta yok olma tehlikesi önemli bir sorundur. Bu çalışmanın amacı, Göbekli Tepe’yi arkeolojik boyutundan farklı olarak burada yaşayan halkın bir “yer” olarak Göbekli Tepe ile olan sosyo- mekansal ilişkisini anlamaya çalışmaktır. Çalışmada nitel araştırma yöntemi kullanılmış olup, araştırma kapsamında Göbekli Tepe çevresindeki altı köyde yaşayan 20 katılımcı ile görüşmeler yapılmıştır. Görüşmeler sonucunda elde edilen bulgulara göre; keşif sonrasında yerel halkın bir yer olarak anlam yükledikleri Göbekli Tepe ile olan bağı koparılmış ve yeniden üretilen Göbekli Tepe, bölge insanının yabancı kaldığı bir müşterek mekân haline dönüşmüştür. Göbekli Tepe’nin bir meta olarak görsel tüketime dayanan turistik bir merkeze dönüştürülmesi yoluyla ülke içinden ve dışından birçok insanın buraya gelmesi sağlanırken, yıllardır bu yerin gerçek sahipleri olan yerel halkın ötekileş(tiril)erek bu yerle bağlarının koparılması önemli bir tartışma konusudur.
TOPLUMSAL VE SİYASAL BİR İLİŞKİ TİPİ OLARAK KAYIRMACILIK VE BAZI YENİ KAVRAMSALLAŞTIRMALAR
Authors: ÖZEL Mesut
Published: October 2021

Toplumsal bir ilişki sistemi olarak kayırmacılık, ilişkiye kaynaklık eden temalara göre farklı kavramlarla adlandırılabilmektedir. Gerek kaynakların gerekse ilişkiye kaynaklık eden temellerin çeşitliliğinden hareketle ortaya çıkan bu kavramlar konusunda literatürde kavramsal kaotik bir durum olduğu görülmektedir. Konunun ve kavramların daha netleştirilip çerçevelendirilmesi adına bu çalışmada, öncelikle konuya ilişkin kavramların belirginleştirilmesi ve sonrasında literatürde yer almayan sahadaki yeni kayırmacı ilişki tiplerinin kavramsallaştırılmasına çalışılmıştır. Bu çerçevede bu çalışmada 2019 yılı içerisinde kamu istihdamında güvenlik soruşturması, mülakat gibi yasal düzenlemeler dolayısıyla kayırmacı ilişkilere imkân veren kadrolara (kaymakam, hâkim/savcı, denetmen gibi) atanmalar üzerinden bu tür ilişkilerin incelendiği bir nitel sosyolojik çalışmadan elde edilen, sahaya ve literatüre ilişkin verilerden faydalanılmıştır. Bu bağlamda saha ve literatür araştırmasından hareketle; makro düzey bir etno-dinsel ayrımcılığa işaret eden yapısal kayırmacılık, yeni pozisyonlar açabilmek için var olan pozisyonları işgal edenlerin tasfiyesini içeren dışlayıcı/uç kayırmacılık ve yasalar aracılığıyla işleyen bir tür olarak radikal kayırmacılık şeklinde yeni kavramsallaştırmalara ulaşılmıştır.
SOSYAL BİLİMLERDE ÇELİŞKİSİZ VE SINIRLANMAYAN BİR BETİMLEME İÇİN HERMENÖTİK FENOMENOLOJİ: YÖNTEMBİLİM VE “ORMAN YOLU”
Authors: ARAŞAN Ahmet
Published: October 2021

Husserl’in temellerini attığı yeni “kesin bilim”, fenomenoloji, dünyadaki “şey”leri teorilere değil, insanların yaşadıkları deneyimlerin üzerinde yönelimsellik içerisinde düşünmelerine başvurarak betimlemeyi öngörmektedir. Öznelliğe dönüş olarak kabul edilen bu yaklaşım, yorumlayıcı sosyal bilimler araştırmalarında yaygın şekilde yer bulmaktadır. Ancak, son derece meşru “ne” sorusuna cevap veren fenomenoloji, sosyal bilimlere uyarlanırken bazı kısıt ve çelişkiler içerir: yöntemini oluşturan “ayraca almak” imkansızdır, derin anlamlara erişemez, toplumsal etkileşime önem vermez ve yorumlayıcı yaklaşımlarla kullanılırken pozitivizmin etkisine açıktır. Peki bu sorunlar sosyal araştırmalarda doyurucu bir betimleme yapılamayacağı anlamına mı gelir? Özellikle Heidegger ve Gadamer tüm bunları aşmak adına hermenötik felsefesini geliştirmişler, eğitim bilimci van Manen ise bu felsefenin sosyal bilimler araştırmalarında kullanılmasını sağlayacak bir yöntembilim ortaya koymuştur. Bu araştırmanın amacı bu felsefelerin sosyal bilimlere yansımalarındaki sorunları öne çıkartıp yeni bir “yol” önermektir. Araştırma, Husserlci betimlemenin sosyal bilimlerdeki kullanımında ortaya çıkan kısıt ve çelişkilerini inceledikten sonra, hermenötik felsefesine ve ondan yola çıkarak “ne” sorusuyla birlikte “nasıl” sorusuna da cevap vermek üzere geliştirilen hermenötik fenomenoloji yöntembilimine eğilmektedir. Yöntemi kabul etmeyen bu yöntembilimle kullanılmak üzere geliştirilen “orman yolu” kavramı da anlatılmaktadır.
Endoscopic Surgery Outcomes in Patients With Rhino-Orbito-Sinusal Mucormycosis
Authors: Meybodian Mojtaba , Baradaranfar Mohammadhossein , Vaziribozorg Sedighe , Mahmoodifar Samira
Published: October 2021

The aim of this study is to evaluate the response to endoscopic treatment and treatment outcomes in patients with rhino-orbito-sinusal mucormycosis. In this descriptive cross-sectional study, 19 patients with rhino-orbito-sinusal mucormycosis were involved. Data such as age, gender, the 6-month survival rate of the patients, type of underlying disease, site of involvement, number of endoscopic procedures, history of exenterating of the eye, type of received systemic treatments, and the time interval between the onset of symptoms and the start of treatment were recorded and analyzed. The 6-month outcome analysis showed that 10 out of 19 patients (58.8%) survived. The results also revealed no significant difference in the 6-month survival rate according to parameters such as gender, underlying disease (57.9% of the patients had diabetes and 42.1% had cancer), age, delay in surgery, site of involvement, and the number of surgeries (P>0.05). However, there was a significant difference in the 6-month survival rates of patients with respect to exenterating of the eye (P<0.05). According to our results, uncontrolled diabetes is the most common underlying cause of rhino-orbito-sinusal mucormycosis. It also seems that exenterating of the eye affects the survival rate of patients. This study suggests that timely and early diagnosis as well as correct treatment, endoscopic procedure, if possible, play an important role in the prognosis of the disease and can greatly reduce the mortality rate.
A Rare Case of Pregnancy Complicated by Bladder Exstrophy and Uterine Prolapse
Authors: Pourali Leila , Ghorbani Hamidreza , Vatanchi Atiyeh , Ayati Sedigheh , Ghasemi Ghazal , Golzar Azimeh
Published: October 2021

Uterine prolapse and bladder exstrophy (BE) during pregnancy is a rare condition. The aim of this study was to present a rare case of pregnancy complicated by both bladder exstrophy and uterine prolapse. A 39-year-old pregnant woman (gravida 2, para 1) presented to the maternity department at 39 weeks of gestation with labor pain. Physical examination showed regular uterine contractions; the cervix was completely out of the vaginal opening with dilatation of 3 cm and effacement of 30%. She had a history of multiple surgeries for correction of bladder exstrophy and also suffered from uterine prolapse. In active labor, abnormal fetal heart rate tracing happened, so an emergent cesarean section was planned, and a healthy neonate with the normal Apgar score was born. At regular follow-up until four months after delivery, there was no sign or symptom of uterine proplase. Multidisciplinary management of patients with BE and uterine prolapse may result in optimal perinatal outcomes. Uterine prolapse may disappear after delivery, even in the complicated case of bladder exstrophy.
Analysis of the Influence of Communication on Employee Performance Satisfaction with Supervision as a Mediating Variable at Private Contractor Company
Authors: Jinqiang Shi
Published: October 2021

Private project worker organization in Medan declined as of late. Decrease in Representative Fulfillment is brought about by a few things; diminished nature of correspondence and management. The examination tests were drawn by utilizing the immersion recipe comprising of 70 representatives. The halfway testing showed that correspondence has a positive and huge impact on representative fulfillment, wherein the T-count is 4.392 and the worth of T-table is 1.66691, then, at that point, the worth of T-count> T-table (4.392> 1.66691) with huge worth of 0,000> 0.05. The incomplete testing showed that management has a positive and huge impact on worker work fulfillment, in which the worth of oversight variable T-count 2.015> T-table 1.66691 with an importance worth of 0.005> 0.05. All the while, correspondence and management have a positive and critical impact on worker work fulfillment up to 15,467 in which F-table is 2.74.
Evaluation of developmental competence of Sus scrofa domesticus (L.) oocyte-cumulus complexes after intra- and extraovarian vitrification
Authors: Kuzmina T. I. , Chistyakova I. V.
Published: October 2021

The aim of the present study was to identify the influence of extra- (EOV) and intraovarian vitrification (IOV) on mitochondrial activity (MA) and chromatin state in porcine oocytes during maturation in vitro. During EOV porcine oocytes were exposed in cryoprotective solutions (CPS): CPS-1 – 0.7 M dimethyl sulfoxide (DMSO)+0.9 M ethylene glycol (EG); CPS-2 – 1.4 M DMSO+1.8 M EG; CPS-3 – 2.8 M DMSO+3.6 M EG+0.65 M trehalose. At IOV the ovarian fragments were exposed in CPS-1 – 7.5 % EG+7.5 % DMSO, then in CPS-2 – 15 % EG, 15 % DMSO and 0.5 M sucrose. Straws with oocytes and ovarian fragments were plunged into LN2 and stored. For devitrification, the EOV oocytes were washed in solutions of 0.25, 0.19 and 0.125 M of trehalose, the IOV – in 0.5 and 0.25 М trehalose. Oocytes were cultured in NCSU-23 medium with 10 % fluid of follicles, follicular walls, hormones. 0.001 % of highly dispersed silica nanoparticles (ICP named after A.A. Chuyko of the NAS of Ukraine) were added to all media. The methods of fertilization and embryo culture are presented in the guidelines developed by us. MA and chromatin state were measured by MitoTracker Orange CMTMRos and the cytogenetic method. Significant differences in the level of oocytes with high-expanded cumulus between control and experimental vitrified groups (81 % versus 59 % and 52 %, respectively, p ≤ 0.001) were observed. The percentage of pyknotic cells in native oocytes was 19 %, EOV or IOV oocytes were 39 % and 49 %, respectively. After culture, the level of matured native oocytes was 86 %, 48 % EOV and 33 % IOV cells finished the maturation (p ≤ 0.001). Differences were also observed in the level of MA between groups treated by EOV and IOV (89.4±7.5 µA and 149.2±11.3 µA, respectively, p ≤ 0.05). For the first time, pre-implantation embryos were obtained from oocytes treated by IOV.
Unusual congenital polydactyly in mini-pigs from the breeding group of the Institute of Cytology and Genetics (Novosibirsk, Russia)
Authors: Nikitin S. V. , Knyazev S. P. , Trifonov V. A. , Proskuryakova A. A. , Shmidt Yu. D. , Shatokhin K. S. , Zaporozhets V. I. , Bashur D. S. , Korshunova E. V. , Ermolaev V. I.
Published: October 2021

The article describes a new phenomenon in the breeding group of mini-pigs at the Institute of Cytology and Genetics (ICG, Novosibirsk): polydactyly (extra digits), which is unusual because the additional digits are situated at the lateral surface of legs or at the lateral and medial ones. This anomaly was first found here in 2017 in adult animals intended for culling due to incorrect positioning of the legs caused by flexor tendon laxity and resulting in weight-bearing on the palmar surface of the proximal phalanges (“bear’s paw”). Therefore, the polydactyly of mini-pigs has a pronounced negative selection effect. A visual survey of the livestock was conducted, and a description of the detected anomaly was compiled. The polydactyly in mini-pigs is a stand-alone trait and is not part of any syndromes. Individuals with polydactyly may have extra digits either on pectoral or on pectoral and pelvic limbs. On thoracic limbs, there may be either one lateral digit or a lateral digit and a medially located rudimentary hooflet. On pelvic limbs, only lateral extra digits can occur. Anatomical and morphological analyses showed that the lateral extra digit is an anatomically complete (“mature”) structure, whereas the medial rudimentary digit consists of only a hooflet without other structures characteristic of normal digits. Cytological examination revealed no specific karyotypic features, except for Robertsonian translocation Rb 16;17 previously reported for the mini-pigs of the same livestock. Cytological findings indicated that the polydactyly and Robertsonian translocation are not linked genetically. Genealogical analysis and results of crosses are consistent with a working hypothesis of recessive inheritance of the trait. Overall, the study shows that this type of polydactyly is anatomically and morphologically unique and not typical of Sus scrofa. In this species, only polydactyly types with medial accessory toes have been described and are usually inherited as a dominant trait with incomplete penetrance. In our case, the results of test crosses indicate recessive inheritance of the trait with varying expression and incomplete penetrance, because of which poorly expressed phenotypes are not visually detectable.
Influence of leptin administration to pregnant female mice on obesity development, taste preferences, and gene expression in the liver and muscles of their male and female offspring
Authors: Denisova E. I. , Savinkova M. M. , Makarova E. N.
Published: October 2021

The consumption of food rich in sugar and fat provokes obesity. Prenatal conditions have an impact on taste preferences and metabolism in the adult offspring, and this impact may manifest differently in different sexes. An increase in blood leptin level in pregnant females reduces the risk of obesity and insulin resistance in the offspring, although the mechanisms mediating this effect are unknown. Neither is it known whether maternal leptin affects taste preferences. In this study, we investigated the effect of leptin administration to pregnant mice on the development of diet-induced obesity, food choice, and gene expression in the liver and muscles of the offspring with regard to sex. Leptin was administered to female mice on days 11, 12, and 13 of pregnancy. In male and female offspring, growth rate and intake of standard chow after weaning, obesity development, gene expression in the liver and muscles, and food choice when kept on a high-calorie diet (standard chow, lard, sweet cookies) were recorded. Leptin administration to pregnant females reduced body weight in the female offspring fed on the standard diet. When the offspring were given a high-calorie diet, leptin administration inhibited obesity development and reduced the consumption of cookies only in males. It also increased the consumption of standard chow and the mRNA levels of genes for the insulin receptor and glucose transporter type 4 in the muscles of both male and female offspring. The results demonstrate that an increase in blood leptin levels in pregnant females has a sex-specific effect on the metabolism of the offspring increasing resistance to obesity only in male offspring. The mechanism underlying this effect includes a shift in food preference in favor of a balanced diet and maintenance of insulin sensitivity in muscle tissues.
Solusi Numerik Persamaan Gelombang Dua Dimensi Dengan Metode Beda Hingga Skema Eksplisit CTCS
Authors: Chasamah Allifia Nur , Jamhuri Muhammad , Alisah Evawati
Published: October 2021

Persamaan gelombang dua dimensi merupakan  persamaan diferensial parsial  yang merupakan representasi dari gelombang permukaan yang dihasilkan oleh aliran air.  Tujuan daripada penelitian ini adalah untuk menganalisis solusi numerik persamaan gelombng dua dimensi dengan menggunakan metode beda hingga skema eksplisit CTCS (Center Time Center Space). Ada beberapa langkah untuk menyelesaiakan persamaan ini, diantaranya diskritisasi pada persamaan gelombang dua, diskritisasi terhadap kondisi awal serta kondisi batasnya dimensi dengan metode beda hingga pusat terhadap waktu dan ruang. Langkah selanjutnya adalah menentukan syarat kestabilan dan syarat konsistensi untuki menunjukkan bahwa solusi numerik tersebut mendekati solusi analitik. Setelah diperoleh syarat kestabilan dan konsistensi dari skema yang digunakan maka simulasi dari skema yang digunakan dapat dilakukan. Hasil simulasi menunjukkan bahwa penggunaan metode beda hingga skema eksplisit CTCS pada persaman gelombang dua dimensi stabil dengan syarat tertentu.  Dari syarat  kekonvergenannya skema eksplisit CTCS pada persamaan gelombang dua dimensi diperoleh order errornya . Selanjutnya untuk penelitian  dapat meneliti tentang solusi analitik persamaan gelombang dua dimensi dengan menggunakan kondisi batas Neumann
Las finalidades del conocimiento escolar en ciencias en las orientaciones curriculares del Ministerio de Educación Nacional de Colombia
Authors: Cárdenas Ana María , Martínez Carmen Alicia
Published: October 2021

Este artículo busca dar cuenta de las finalidades de las orientaciones declaradas en ciencias naturales expedidas por el Ministerio de Educación Nacional de Colombia. Esta es una de las categorías para la caracterización del conocimiento escolar de dichas orientaciones. El estudio se adelanta en el marco del Doctorado Interinstitucional en Educación. La investigación se desarrolló según el enfoque cualitativo desde una perspectiva interpretativa a través del método del estudio de caso. Se examinaron los Lineamientos curriculares, los Estándares básicos de competencias y los Derechos básicos del aprendizaje para el área de ciencias naturales y educación ambiental a través del análisis de contenidos con apoyo del software Atlas.ti. Como resultados se destacan: el aporte del conocimiento escolar en ciencias para la construcción de una ciudadanía responsable; el conocimiento científico como el principal referente de las finalidades; el propósito de desarrollar actitudes, prácticas y valores; y cómo el conocimiento científico se puede convertir en la base para continuar con la formación académica o para afrontar la vida laboral y productiva. Se plantean nuevas necesidades de investigación, por ejemplo, cómo relacionar estas finalidades de formación de ciudadanos con los contenidos propuestos.
Disputas narrativas y enseñanza de la historia: aportes de una reflexión teórica
Authors: Cavalcanti Erinaldo
Published: October 2021

En la ciencia histórica, la narrativa ha sido objeto de reflexión de diferentes autores, desde distintos enfoques. Este artículo tiene el fin de ampliar la reflexión sobre la narrativa histórica —académica y didáctica—, para comprender los límites de su pretensión de representar el pasado. Con esta problematización, el objetivo es poner la narrativa como foco de análisis en la enseñanza de la historia como una posible forma de enfrentar las disputas narrativas que son parte de la rutina del aula. La metodología parte del análisis crítico de literatura especializada, con el objetivo de entender en qué consisten los criterios que dan legitimidad a la narrativa histórica. En conclusión, con base en el marco teórico —especialmente en Paul Ricoeur—, se argumenta que los procedimientos que constituyen la narrativa histórica pueden ser utilizados como una estrategia viable para tratar las disputas narrativas en el aula y promover la comprensión de la relación de confianza y credibilidad de que goza este informe escrito en la tarea para representar el pasado.
aplicação dos precedentes vinculantes
Authors: Olav Smith Carl , Quintas Fabio
Published: October 2021

O presente artigo procura avaliar como os juízes de primeiro grau de jurisdição, em especial os que se encontram em processo de vitaliciamento, veem o sistema de decisões vinculantes instituído pelo CPC/2015, principalmente quando lidam com demandas de massa. Parte-se da premissa de que a independência judicial, como um pressuposto do Estado de Direito, significa que o jurisdicionado tem o direito de receber uma tutela jurisdicional necessariamente fundamentada no ordenamento jurídico (direito pré-existente) e que o convencimento do julgador seja livre de pressões estranhas ao processo. Por isso, o julgador necessariamente deve considerar as decisões vinculantes, assumindo, caso entenda existir a hipótese de distinguishing ou overruling, um dever adicional de argumentação, sob pena de nulidade da decisão. Defende-se, nessa linha, que a vinculação a precedentes não afronta a independência judicial. Dito isto, realizou-se pesquisa empírica junto aos juízes que participaram do módulo nacional do curso de formação inicial da Escola Nacional de Formação e Aperfeiçoamento de Magistrados, obrigatório para todos que ingressam na carreira da magistratura, na qual é possível verificar a forte adesão dessa parcela de magistrados brasileiros ao sistema de decisões vinculantes.
Modelación matemática y computacional de una inundación: de Villahermosa, Tabasco, México
Authors: Alavez Ramírez Justino
Published: October 2021

A raíz de la histórica inundación ocurrida en Tabasco a finales de octubre y principios de noviembre de 2007, un grupo de profesores integrados por el Dr. Justino Alavez Ramírez, M.C. Jorge López López, L.M. Juan Luis Hernández López y M.C. Adriana De la Cruz Uribe, impulsamos desde el principio de diciembre de ese mismo año, un seminario que lo denominamos “Simulación Numérica de Avenidas y Zonas Inundables”, cuyo propósito fue estudiar y desarrollar modelos matemáticos y computacionales que nos permitieran simular numéricamente el desborde de las principales avenidas fluviales que cruzan por la ciudad de Villahermosa, Tabasco; y de esa manera poder simular escenarios futuros de otras posibles inundaciones de la ciudad de Villahermosa.
Producción porcina del estado de Tabasco
Authors: López Naranjo José Isabel
Published: October 2021

En la actualidad la producción de alimentos de origen vegetal y animal se ha visto disminuida de tal forma que en muchos países del mundo existen grandes carencias y desabasto que ha contribuido a la presencia de altos índices de desnutrición en la población. La Organización de las Naciones Unidas para la Agricultura y la Alimentación (por sus siglas en inglés FAO) realizó el estudio “El futuro de la alimentación y la agricultura: tendencias y desafíos”, el cual pronostica la producción de alimentos en un horizonte de los próximos 50 años y reporta datos que indican un gran déficit en la elaboración y generación de alimentos en cantidad y calidad para la humanidad. Esto indica un agudizamiento de la crisis alimentaria en el mundo por lo que propone una serie de estrategias que tienden a prevenir este fenómeno, encontrándose la reconversión del campo y la inversión en ciencia y tecnología para paliar esta situación en los años venideros.
Lenguajes y Autómatas: Una perspectiva funcional con Racket
Authors: Cáceres González Abdiel E
Published: October 2021

Este libro es el resultado de algunos años de coleccionar y mejorar funciones que se han empleado en cursos de Lenguajes Formales y Autómatas, en la Universidad Juárez Autónoma de Tabasco, en México. El contenido de este material abarca diferentes temas fundamentales, desde lógica proposicional hasta la teoría clásica de autómatas finitos. El enfoque presentado es completametne práctico, programando casi todas las funciones matemáticas que usualmente se estudian solamente en teoría, en prácticamente la mayoría de los libros de texto. Se ha empleado el lenguaje de programación DrRacket para implementar las funciones matemáticas, porque es un lenguaje con una sintaxis muy simple y fácil de aprender, lo cual es sumamente útil para expresar en código las ideas y conceptos de la teoría de lenguajes formales y autómatas finitos.
Manual para la producción de róbalo blanco: (Centropomus undecimalis) en cautiverio
Authors: Contreras Sánchez Wilfrido Miguel , Contreras García María de Jesús , Mcdonal Vera Alejandro , Cruz Rosado Alejandro , Martínez García Rafael
Published: October 2021

Por su importancia económica y soporte de grandes pesquerías en el Golfo de México, se considera al robalo blanco como uno de los peces más importantes tanto para los pescadores ribereños como para los de aguas marinas, por ello la importancia de generar información para la reproducción de esta especie en condiciones de cautiverio, lo que permitirá no solo la repoblación de cuerpos de agua sino también su producción y engorda involucrando a los pescadores creando conciencia en la necesidad de producir para cosechar.
Análisis de regresión aplicado
Authors: López Naranjo José Isabel , Osorio Osorio Rodolfo
Published: October 2021

El análisis de regresión es una herramienta de la inferencia estadística aplicada que permite ajustar conjunto de datos proveniente de trabajos de investigación con propósitos de predicción. En esta obra se trata una diversidad de técnicas útiles en esta tarea y se proporcionan las estrategias que permiten la selección de las variables, el tamaño de muestra y el mejor modelo; aquél que explique de mejor manera la relación entre las variables estudiadas. Esta técnica es aplicable en cualquier área de las ciencias: agropecuarias, biológica, económica, salud, genética, matemáticas, del comportamiento humano, etc., donde los objetivos incluyan predicción de resultados futuros de la variable respuesta (dependiente).
Adherence to treatment in patients with inflammatory bowel disease
Authors: Andreev K. A. , Gorbenko A. V. , Skirdenko Yu. P. , Nikolaev N. A. , Livzan M. A. , Bikbavova G. R. , Fedorin M. M.
Published: October 2021

Inflammatory bowel disease (IBD) is a common pathology that reduces the quality and duration of a patient’s life. The cornerstone of treatment of IBD patients is polypharmacotherapy based on the use of salicylates, antibiotics, immunomodulatory and biological drugs, and topical dosage forms. Multicomponent treatment has shown to reduce the quality of life and negatively affect adherence to drug therapy in IBD patients.One of the leading causes of treatment failure is low treatment adherence, which leads to disease progression, disability, and increased financial costs. Currently, there are many factors that affect adherence to therapy, some of them are modifiable, which creates opportunities to improve the effectiveness of existing medical interventions. However, the available data on the level of adherence in IBD patients are not numerous and homogeneous, so a low level of adherence to drug therapy in IBD patients is registered in 7–72% of cases.An important issue in understanding adherence in IBD patients is a lack of research on the level of adherence to counselling and lifestyle modification. However, the course of IBD, treatment features related to the duration of therapy and necessary lifestyle modifications (nutrition), as well as regular monitoring of laboratory and instrumental parameters determine the need to assess adherence to lifestyle modification and counselling along with adherence to drug therapy.
Estimation of the effect of lithium salts on cytokine production by blood cells in in vitro experiments
Authors: Vetlugina T. R. , Epimakhova E. V. , Savochkina D. N. , Plotnikov E. V. , Boiko A. S. , Ivanova S. A. , Bokhan N. A.
Published: October 2021

Aim. To study the effects of lithium salts on production of cytokines by immunocompetent cells in the whole-blood culture of patients with alcohol dependence and affective disorders.Materials and methods. The study materials were blood samples from 25 patients with alcohol dependence (AD) and 12 patients with bipolar disorder (BD). Blood diluted 1:1 with complete RPMI-1640 medium (Gibco, UK) was added to the wells of the culture plate, then new lithium salts (succinate, fumarate, pyruvate, ascorbate) and a reference salt – lithium carbonate at a final concentration of 1.2 mmol / l per lithium ion – were added. In parallel, control samples without lithium salts were tested; the samples were incubated for a day. The concentration of cytokines (interferon (IFN) γ, interleukin (IL)-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-17A, tumor necrosis factor (TNF) α) was determined in the culture supernatants on the MAGPIX multiplex analyzer (Luminex, USA) (Center for Collective Use “Medical Genomics”, Tomsk NRMC) using the Human Cytokine / Chemokine Magnetic Bead Panel (Merck, Germany).Results. All lithium salts had a unidirectional effect on the production of cytokines by immunocompetent cells (ICC), except for lithium ascorbate and IL-8. The concentrations of cytokines in the supernatants of loaded and control samples (spontaneous production) were comparable, which indicates an absence of stimulating or suppressing effects of salts on the functional activity of ICC under the experimental conditions. The effect of lithium ascorbate as an IL-8 inducer was detected: the production of IL-8 induced by lithium ascorbate was 2.3–2.5 times higher than its spontaneous production.Conclusion. The obtained results, as well as the previously revealed antioxidant and cytoprotective properties of new lithium salts, confirmed that they are promising for development of pharmacological agents with combined action.
A clinical case of idiopathic pulmonary fibrosis against the background of comorbid pathology
Authors: Teteneva A. V. , Kalyuzhin V. V. , Chernyavskaya G. M. , Bespalova I. D. , Chernogoryuk G. E. , Zavadovskaya V. D. , Zhogina T. V. , Ustyuzhanina E. A. , Kuzin E. V. , Varfolomeeva I. A. , Sedlyar O. V. , Medikova E. A. , Koshchavtseva Yu. I. , Potapov K. V. , Karzilov A. I. , Porovsky Ya. V. , Solovev M. M.
Published: October 2021

Idiopathic pulmonary fibrosis (IPF) is one of the most common diseases in the group of interstitial lung diseases, which is characterized by persistent progression and poor prognosis. Over the past decade, experts have made significant progress in developing a diagnostic algorithm for IPF patients. This algorithm includes analysis of clinical, laboratory, and instrumental data, primarily the results of high-resolution computed tomography (HRCT). Precise adherence to the diagnostic algorithm and correct interpretation of HRCT data are prerequisites for IPF diagnosis.Specialists of the Tomsk region have developed routing of patients with suspected IPF. The presented clinical case is a successful example of adhering to this algorithm. Wide implementation of modern diagnostic algorithms into diagnosis and treatment of IPF and quality improvement of imaging methods, primarily HRCT, carried out as a part of the differential diagnosis, open up prospects for early diagnosis of this pathology. A timely prescribed antifibrotic therapy (nintedanib, pirfenidone) in IPF allows to slow down pathological progression and improves the prognosis.
Influence of a B16/F10 melanoma variant on the Вcl-2 levels in mitochondria in various organs of female mice
Authors: Kit O. I. , Frantsiyants E. M. , Neskubina I. V. , Cheryarina N. D. , Shikhlyarova A. I. , Surikova E. I. , Kaplieva I. V. , Nemashkalova L. A.
Published: October 2021

Aim. To study the Bcl-2 level in mitochondria of various organs in female mice with standard and stimulated growth of an experimental B16/F10 melanoma.Materials and methods. The study included С57ВL/6 female mice (n = 168). The experimental animals were divided into the following groups: an intact group (n = 21), a group with modelled chronic neuropathic pain (CNP) (n = 21), an M group with B16/F10 melanoma (n = 63), and a CNP + M group (n = 63). The Bcl-2 concentration (ng / mg protein) in mitochondrial samples was determined by ELISA (Thermo Fisher Scientific, Austria). Statistical analysis of the results was carried out using Statistica 10.0.Results. Compared to the Bcl-2 levels in the intact animals, CNP decreased this parameter in the cardiac mitochondria by 1.3 times, while increasing it by 5.9 times in the skin mitochondria. In the dynamics of standard melanoma growth, the Bcl-2 content changed compared with the corresponding intact values in the mitochondria of the brain, heart, and skin, but did not change in the liver and kidneys. In the mitochondria in melanoma, the Bcl-2 levels were high throughout the entire period of standard tumor growth in comparison with the intact skin. The stimulated melanoma growth in CNP was involving more organs into the pathological process as the tumor was growing. Thus, in comparison with the values in the CNP group, the mitochondrial Bcl-2 levels changed in the heart at week 1; in the heart and skin – at week 2; in the heart, skin, and brain – at week 3. The Bcl-2 levels did not change in the liver and kidney mitochondria. In the mitochondria in the CNP-stimulated melanoma, the Bcl-2 levels were lower than in the skin mitochondria in CNP throughout the entire tumor growth period.Conclusion. The liver and kidney mitochondria are somewhat Bcl-2 stable in both standard and stimulated tumor growth. It is assumed that different Bcl-2 dynamics in the mitochondria in melanoma depending on the variant of tumor development reflects the modulating effect of CNP and the ability to change the Bcl-2 levels according to the growth phase.
Neurovisualization features of brain anatomy in children with spastic cerebral palsy revealed by magnetic resonance tractography
Authors: Klyuev E. A. , Sheiko G. E. , Dunaev M. G. , Lobanova E. V. , Rasteryaeva M. V. , Sharabrin E. D.
Published: October 2021

Aim. To perform quantitative evaluation of the degree of white matter tract abnormalities in children with spastic cerebral palsy by magnetic resonance tractography to determine severity of the disease, as well as to carry out a dynamic assessment of treatment effectiveness.Materials and methods. The study included 46 children (32 males, 14 females; average age 5.4 ± 1.1 years). The participants were divided into two groups. The experimental group consisted of 23 children with spastic cerebral palsy. The control group included 23 children without any neurological disorder. Examination of the brain was performed on the Siemens Essenza 1,5 Т system (Siemens, Germany) and included magnetic resonance tractography to reconstruct the major white matter tracts. The number of fibers, average fractional anisotropy value, apparent diffusion coefficient, and coefficient of myelination of major white matter tracts in the brain were calculated and analyzed.Results. We found a significant difference in the above-stated parameters between the groups. The experimental group showed a decrease in the absolute number of fibers at the central and posterior segments of the corpus callosum, corticospinal tracts, and left inferior longitudinal fasciculus. Besides, we detected a decrease in fractional anisotropy at 2–5 segments of the corpus callosum and right lateral corticospinal tract, an increase in the apparent diffusion coefficient at 2, 4, and 5 segments of the corpus callosum and left lateral corticospinal tract, and a decrease in the myelination coefficient in all the examined tracts, except for superior longitudinal fasciculus. We revealed a positive correlation between the intensity of the motor disturbance and the coefficient of myelination at the anterior corpus callosum and inferior longitudinal fasciculus.Conclusion. Magnetic resonance tractography is an informative technique for unbiased evaluation of white matter tract anatomy, as well the level and degree of motor tract damage. The most useful characteristics of white matter tract anatomy are the absolute number of fibers in the tract, fractional anisotropy, and coefficient of myelination. Some of them correlated with the intensity of motor disturbance, so they can be regarded as potential predictors of rehabilitation potential.
Effects of a high-fat, high-carbohydrate diet on blood cells of rats
Authors: Birulina J. G. , Ivanov V. V. , Buyko E. E. , Trubacheva O. A. , Petrova I. V. , Grechishnikova A. Yu. , Nosarev A. V. , Gusakova S. V.
Published: October 2021

Aim. To study the effects of a high-fat, high-carbohydrate diet on erythrocytes and platelets of rats.Materials and methods. Male Wistar rats (n = 23) were used for the study. The rats were divided into a control group and an experimental group. The rats from the control group were fed with standard rat chow. The rats from the experimental group had received a high-fat and high-carbohydrate diet for 12 weeks. In the rats, body weight and blood pressure (BP) were measured, an oral glucose tolerance test was carried out, and hematological and lipid metabolism parameters were analyzed. The conductance of erythrocyte KCa-channels was measured by the potentiometric method, and platelet aggregation was determined by the turbidimetric method.Results. Feeding the rats with a high-fat, high-carbohydrate diet for 12 weeks resulted in obesity, BP elevation, hyperglycemia, impaired glucose tolerance, and dyslipidemia with pronounced triglyceridemia. In the experimental group, a rise in the number of leukocytes, mainly due to granulocytes, and an increase in the number of platelets and their collagen-induced aggregation were observed. The red blood cell count in the rats of the experimental group did not significantly differ from that of the control group. In the experimental group, multidirectional changes in the membrane potential were observed in response to the stimulation of the KCa-channels in the erythrocyte membrane with the Ca2+ ionophore A23187 or artificial redox systems.Conclusion. The obtained data indicate that a high-fat, high-carbohydrate diet leads to metabolic and hemorheological disorders that are typical of metabolic syndrome.
The structure of affective fluctuations in a non-clinical sample
Authors: Osipova N. N. , Bardenstein L. M. , Aleshkina G. A. , Dmitrieva E. V.
Published: October 2021

Aim. To study the structure of mood fluctuations at the preclinical stage based on the findings of screening methods.Materials and methods. A total of 129 students participated in the study. The average age was 18.95 ± 0.08 years. We used the clinical and psychopathological method, the Mini-International Neuropsychiatric Interview (MINI), and screening methods, such as the diagnostic questionnaire for bipolar disorder (Hypomania Checklist-32 (HCL-32)), and Hamilton Depression Scale (HAMD-17).Results. Upon a clinical and psychopathological examination according to ICD-10 criteria, class V, mental and behavioral disorders (F00-F99), including affective pathology, were not detected. According to the findings of the HCL-32 screening technique, 61.2% (n = 79) of respondents had a cumulative score above the threshold. Analysis of individual items on the HCL-32 scale across the entire sample revealed that the majority of examinees positively assessed the impact of mood elevations on the family sphere (63.57%; n = 82), social activities (68.99%; n = 89), work (75.19%; n = 91), and recreational sphere (82.17%; n = 106). Positive (36.43%; n = 47; 95% confidence interval (CI) 28.13–44.74) and neutral (37.21%; n = 48; 95% CI 33.35–50.37) assessments of mood elevations were also detected by the respondents’ immediate circle, which, in general, significantly complicates recognition of hypomania symptoms and delays seeking specialized care. In the structure of mood elevation episodes irritability (r = –0.684), conflict (r = –0.665), risk-taking behavior (r = –0.550), increased sexual desire (r = 0.527), increased energy and activity (r = 0.431), distractibility (r = –0.467), stimulant use (r = –0.467), and decreased need for sleep (r = 0.408) dominated. These signs are very similar to the clinical manifestations of a hypomanic episode in bipolar II disorder.Signs of mild depression revealed according to the HAMD-17 scale in 34.8% (n = 45) of respondents included sleep disorders (r = 0.693), decreased ability to work (r = 0.520), depressive mood (r = 0.579), hypochondria (r = 0.466), general somatic symptoms (r = –0.508), and gastrointestinal disorders (r = 0.513). These signs did not result in chief complaints and were not the reason for seeking specialized care.Conclusion. In the non-clinical sample, in the structure of mood swings, mood elevations dominated, which were not subjectively identified as illness symptoms and did not appear as complaints in clinical and psychopathological examinations. Low mood was accompanied by general somatic symptoms, which may indicate subsequent formation of comorbid pathology. The identified subsyndromal signs of hypomania and depression in the nonclinical sample in the absence of complaints and psychiatric care-seeking are of clinical significance as predictors of a bipolar affective disorder and require further clinical and dynamic monitoring.
Adoption of Recommended Technologies by farmers in Coconut Crop
Authors: M. Priyadharshini M. Jeyalakshmi , Narmatha A.
Published: October 2021

In India, coconut farming is inseparably embedded in the socio-historical culture as well as the ethnic identity. Coconut is also interlinked with socio- economic life of a large number of small and marginal farmers in peninsular India. Coconut is a source of food, beverage, medicine, natural fibre, fuel, wood and raw materials for units producing a variety of goods. It is estimated that about 12 million people in India are dependent on the coconut sector in areas of cultivation, processing and trading activities. Hence, The study was conducted in two blocks of Theni district (coconut), with a sample size of 40 respondents. The findings of the study revealed that the adoption of recommended technologies was found to be high in variety selection, fertilizer application, plant protection measures and low in seedling rate / hec, recommended spacing and weed management.