bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure Legends 1-5 from RAP80 Is Critical in Maintaining Genomic Stability and Suppressing Tumor Development
Authors: Yin Zhengyu , Menendez Daniel , Resnick Michael A. , French John E. , Janardhan Kyathanahalli S. , Jetten Anton M.
Published: April 2023

PDF file - 71K
Supplementary Figure 5 from RAP80 Is Critical in Maintaining Genomic Stability and Suppressing Tumor Development
Authors: Yin Zhengyu , Menendez Daniel , Resnick Michael A. , French John E. , Janardhan Kyathanahalli S. , Jetten Anton M.
Published: April 2023

PDF file - 276K, Histopathological examination of tumor tissues
Supplementary Table 1 from Characterization of Gene–Environment Interactions for Colorectal Cancer Susceptibility Loci
Authors: Hutter Carolyn M. , Chang-Claude Jenny , Slattery Martha L. , Pflugeisen Bethann M. , Lin Yi , Duggan David , Nan Hongmei , Lemire Mathieu , Rangrej Jagadish , Figueiredo Jane C. , Jiao Shuo , Harrison Tabitha A. , Liu Yan , Chen Lin S. , Stelling Deanna L. , Warnick Greg S. , Hoffmeister Michael , Küry Sébastien , Fuchs Charles S. , Giovannucci Edward , Hazra Aditi , Kraft Peter , Hunter David J. , Gallinger Steven , Zanke Brent W. , Brenner Hermann , Frank Bernd , Ma Jing , Ulrich Cornelia M. , White Emily , Newcomb Polly A. , Kooperberg Charles , LaCroix Andrea Z. , Prentice Ross L. , Jackson Rebecca D. , Schoen Robert E. , Chanock Stephen J. , Berndt Sonja I. , Hayes Richard B. , Caan Bette J. , Potter John D. , Hsu Li , Bézieau Stéphane , Chan Andrew T. , Hudson Thomas J. , Peters Ulrike
Published: April 2023

PDF file - 168K, SNP details by study.
Supplementary Figure 2 from RAP80 Is Critical in Maintaining Genomic Stability and Suppressing Tumor Development
Authors: Yin Zhengyu , Menendez Daniel , Resnick Michael A. , French John E. , Janardhan Kyathanahalli S. , Jetten Anton M.
Published: April 2023

PDF file - 34K, Comparison of the IR sensitivity between WT and RAP80-/- mice
Supplementary Figure 1 from RAP80 Is Critical in Maintaining Genomic Stability and Suppressing Tumor Development
Authors: Yin Zhengyu , Menendez Daniel , Resnick Michael A. , French John E. , Janardhan Kyathanahalli S. , Jetten Anton M.
Published: April 2023

PDF file - 518K, RAP80-/- MEFs undergo early senescence
Supplementary Table 3 from Hypoxia-Induced Gene Expression in Chemoradioresistant Cervical Cancer Revealed by Dynamic Contrast-Enhanced MRI
Authors: Halle Cathinka , Andersen Erlend , Lando Malin , Aarnes Eva-Katrine , Hasvold Grete , Holden Marit , Syljuåsen Randi G. , Sundfør Kolbein , Kristensen Gunnar B. , Holm Ruth , Malinen Eirik , Lyng Heidi
Published: April 2023

PDF file - 38K, Gene sets associated with ABrix
Supplementary Methods from Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis
Authors: Zhang Yaqing , Morris John P. , Yan Wei , Schofield Heather K. , Gurney Austin , Simeone Diane M. , Millar Sarah E. , Hoey Timothy , Hebrok Matthias , Pasca di Magliano Marina
Published: April 2023

PDF file - 191K, Detailed experimental procedures including tables for the antibodies and primers used in our study, as well as additional references.
Supplementary Figure Legend from Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis
Authors: Zhang Yaqing , Morris John P. , Yan Wei , Schofield Heather K. , Gurney Austin , Simeone Diane M. , Millar Sarah E. , Hoey Timothy , Hebrok Matthias , Pasca di Magliano Marina
Published: April 2023

PDF file - 157K
Supplementary Figure 8 from Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis
Authors: Zhang Yaqing , Morris John P. , Yan Wei , Schofield Heather K. , Gurney Austin , Simeone Diane M. , Millar Sarah E. , Hoey Timothy , Hebrok Matthias , Pasca di Magliano Marina
Published: April 2023

PDF file - 1428K, Supplemental Figure 8. Wnt/β-catenin signaling regulates PanIN survival.
Supplementary Figure 2 from Hypoxia-Induced Gene Expression in Chemoradioresistant Cervical Cancer Revealed by Dynamic Contrast-Enhanced MRI
Authors: Halle Cathinka , Andersen Erlend , Lando Malin , Aarnes Eva-Katrine , Hasvold Grete , Holden Marit , Syljuåsen Randi G. , Sundfør Kolbein , Kristensen Gunnar B. , Holm Ruth , Malinen Eirik , Lyng Heidi
Published: April 2023

PDF file - 97K, Hypoxia treatment of cervical cancer cell lines
Supplementary Figure 4 from Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis
Authors: Zhang Yaqing , Morris John P. , Yan Wei , Schofield Heather K. , Gurney Austin , Simeone Diane M. , Millar Sarah E. , Hoey Timothy , Hebrok Matthias , Pasca di Magliano Marina
Published: April 2023

PDF file - 572K, Supplemental Figure 4. IHC staining of MUC1, MMP7 and Cleaved Caspase 3 in KC and KDC pancreas.
Supplementary Figure 4 from Skin-Test Infiltrating Lymphocytes Early Predict Clinical Outcome of Dendritic Cell–Based Vaccination in Metastatic Melanoma
Authors: Aarntzen Erik H.J.G. , Bol Kalijn , Schreibelt Gerty , Jacobs Joannes F.M. , Lesterhuis W. Joost , Van Rossum Michelle M. , Adema Gosse J. , Figdor Carl G. , Punt Cornelis J.A. , De Vries I. Jolanda M.
Published: April 2023

PDF file - 30K, Levels of induration according to SKIL classification: Regardless of the number of epitopes or the increasingly stringent criteria for TAA-specific immune responses; the maximum induration at the injection site was similar in all groups. One-way ANOVA was used for comparison of induration in groups of patients with increasing breadth of TAA-specific CD8+ T cell responses. Student t-test was used for comparison of induration in groups of patients as defined by different SKIL criteria
Supplementary Figure 1 from Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis
Authors: Zhang Yaqing , Morris John P. , Yan Wei , Schofield Heather K. , Gurney Austin , Simeone Diane M. , Millar Sarah E. , Hoey Timothy , Hebrok Matthias , Pasca di Magliano Marina
Published: April 2023

PDF file - 892K, Supplemental Figure 1. β-catenin inactivation prevents PanIn formation.
Supplementary Figure 1 from Skin-Test Infiltrating Lymphocytes Early Predict Clinical Outcome of Dendritic Cell–Based Vaccination in Metastatic Melanoma
Authors: Aarntzen Erik H.J.G. , Bol Kalijn , Schreibelt Gerty , Jacobs Joannes F.M. , Lesterhuis W. Joost , Van Rossum Michelle M. , Adema Gosse J. , Figdor Carl G. , Punt Cornelis J.A. , De Vries I. Jolanda M.
Published: April 2023

PDF file - 34K, Schedule of treatment and monitoring:Patients received 3 vaccinations a biweekly interval, followed a delayed type hypersensitivity (DTH) skin test. After completing one cycle and if no progression of disease was confirmed on CT-scan, patients were eligible to receive a maximum of two more cycles and were followed up to 5 years. Abbreviations: Vx = visit x; M = month, D = day, W = week, Y = year, vacx = vaccination x; FU = follow-up; * follow-up visits were planned every 3 months; # CT-scans were planned every 6 months
Supplementary Figure Legends 1-7 from Suppression of the Epithelial–Mesenchymal Transition by Grainyhead-like-2
Authors: Cieply Benjamin , Riley Philip , Pifer Phillip M. , Widmeyer Joseph , Addison Joseph B. , Ivanov Alexey V. , Denvir James , Frisch Steven M.
Published: April 2023

PDF file - 1MB
Supplementary Methods from Autophagy Induced by Conventional Chemotherapy Mediates Tumor Cell Sensitivity to Immunotherapy
Authors: Ramakrishnan Rupal , Huang Chun , Cho Hyun-Il , Lloyd Mark , Johnson Joseph , Ren Xiubao , Altiok Soner , Sullivan Daniel , Weber Jeffrey , Celis Esteban , Gabrilovich Dmitry I.
Published: April 2023

PDF file - 104K
Supplementary Figure S3 from Radioresistant Cancer Cells Can Be Conditioned to Enter Senescence by mTOR Inhibition
Authors: Nam Hae Yun , Han Myung Woul , Chang Hyo Won , Lee Yoon Sun , Lee Myungjin , Lee Hyang Ju , Lee Byoung Wook , Lee Hee Jin , Lee Kyung Eun , Jung Min Kyo , Jeon Hyesung , Choi Seung-Ho , Park Neung Hwa , Kim Sang Yoon , Kim Seong Who
Published: April 2023

Supplementary Figure S3 - PDF file 477K, Combinational treatment of mTOR inhibitor with radiation induces enhanced autophagy activation
Supplementary Figure S2 from Radioresistant Cancer Cells Can Be Conditioned to Enter Senescence by mTOR Inhibition
Authors: Nam Hae Yun , Han Myung Woul , Chang Hyo Won , Lee Yoon Sun , Lee Myungjin , Lee Hyang Ju , Lee Byoung Wook , Lee Hee Jin , Lee Kyung Eun , Jung Min Kyo , Jeon Hyesung , Choi Seung-Ho , Park Neung Hwa , Kim Sang Yoon , Kim Seong Who
Published: April 2023

Supplementary Figure S2 PDF - PDF file 414K, Activation of autophagy in AMC-HN-9 cells
Supplementary Methods and Materials, Figures 1-9 from Aptamer-Mediated Blockade of IL4Rα Triggers Apoptosis of MDSCs and Limits Tumor Progression
Authors: Roth Felix , De La Fuente Adriana C. , Vella Jennifer L. , Zoso Alessia , Inverardi Luca , Serafini Paolo
Published: April 2023

PDF file - 155K
Supplementary Figure 9 from Aptamer-Mediated Blockade of IL4Rα Triggers Apoptosis of MDSCs and Limits Tumor Progression
Authors: Roth Felix , De La Fuente Adriana C. , Vella Jennifer L. , Zoso Alessia , Inverardi Luca , Serafini Paolo
Published: April 2023

PDF file - 30K
Supplementary Figure 8 from Aptamer-Mediated Blockade of IL4Rα Triggers Apoptosis of MDSCs and Limits Tumor Progression
Authors: Roth Felix , De La Fuente Adriana C. , Vella Jennifer L. , Zoso Alessia , Inverardi Luca , Serafini Paolo
Published: April 2023

PDF file - 64K
Supplementary Table 1 from Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
Authors: Fiaschi Tania , Marini Alberto , Giannoni Elisa , Taddei Maria Letizia , Gandellini Paolo , De Donatis Alina , Lanciotti Michele , Serni Sergio , Cirri Paolo , Chiarugi Paola
Published: April 2023

PDF file - 3MB, Pathological parameters of individuals from which CAFs have isolated; CAFs have been isolated from surgical biopsy from nine individuals with prostate carcinoma. Table reports the pathological parameters of the patients before surgery (PSA and Biopsy Gleason Score) and after surgery (Anatomy Pathologic Gleason Score and Pathological Stage).
Supplementary Figure 3 from Aptamer-Mediated Blockade of IL4Rα Triggers Apoptosis of MDSCs and Limits Tumor Progression
Authors: Roth Felix , De La Fuente Adriana C. , Vella Jennifer L. , Zoso Alessia , Inverardi Luca , Serafini Paolo
Published: April 2023

PDF file - 61K
Supplementary Methods and Materials and Results from The Antioxidant Tempol Reduces Carcinogenesis and Enhances Survival in Mice When Administered after Nonlethal Total Body Radiation
Authors: Mitchell James B. , Anver Miriam R. , Sowers Anastasia L. , Rosenberg Philip S. , Figueroa Maria , Thetford Angela , Krishna Murali C. , Albert Paul S. , Cook John A.
Published: April 2023

PDf file - 119KB
Supplementary Figure 5 from CD73-Deficient Mice Are Resistant to Carcinogenesis
Authors: Stagg John , Beavis Paul A. , Divisekera Upulie , Liu Mira C.P. , Möller Andreas , Darcy Phillip K. , Smyth Mark J.
Published: April 2023

PDF file - 452K
Supplementary Figure 2 from CD73-Deficient Mice Are Resistant to Carcinogenesis
Authors: Stagg John , Beavis Paul A. , Divisekera Upulie , Liu Mira C.P. , Möller Andreas , Darcy Phillip K. , Smyth Mark J.
Published: April 2023

PDF file - 3.5MB
Supplementary Figure 1 from CD73-Deficient Mice Are Resistant to Carcinogenesis
Authors: Stagg John , Beavis Paul A. , Divisekera Upulie , Liu Mira C.P. , Möller Andreas , Darcy Phillip K. , Smyth Mark J.
Published: April 2023

PDF file - 2.5MB
Supplementary Figure 4 from Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors
Authors: Duraiswamy Jaikumar , Kaluza Karen M. , Freeman Gordon J. , Coukos George
Published: April 2023

Supplementary Figure 4 - PDF file 28K, Combining �CD25 antibody with PD-1 and CTLA-4 blocking antibodies did not show additional benefit in tumor rejection. Survival of mice inoculated with 0.5 x 106 CT26 tumor cells and injected i.p. �CD25 antibody (PC61, 250 �g) 3 days following tumor inoculation. Tumor size of >200mm3 was defined as lack of survival. Each curve is representative of 3 independent experiments of 12 mice per group (ns, p value not significant)
Supplementary Figure 3 from HMGA2 Is a Driver of Tumor Metastasis
Authors: Morishita Asahiro , Zaidi M. Raza , Mitoro Akira , Sankarasharma Devipriya , Szabolcs Matthias , Okada Yasunori , D'Armiento Jeanine , Chada Kiran
Published: April 2023

Supplementary Figure 3 - PDF file 171K, Immunofluorescence analysis of ZEB1 (left), Fibronectin (right) expression in MCF7-Mock and MCF7-HMGA2 cells. Scale bars represent 50 microm. ZEB1 and fibronectin are expressed in the nucleus of MCF7-HMGA2 cells that have undergone the EMT as is consistent with the other EMT markers in Figure 1C
Supplementary Figure Legends 1-7 from Fibulin-3 Promotes Glioma Growth and Resistance through a Novel Paracrine Regulation of Notch Signaling
Authors: Hu Bin , Nandhu Mohan S. , Sim Hosung , Agudelo-Garcia Paula A. , Saldivar Joshua C. , Dolan Claire E. , Mora Maria E. , Nuovo Gerard J. , Cole Susan E. , Viapiano Mariano S.
Published: April 2023

PDF file - 88K
Supplementary Figure 7 from Fibulin-3 Promotes Glioma Growth and Resistance through a Novel Paracrine Regulation of Notch Signaling
Authors: Hu Bin , Nandhu Mohan S. , Sim Hosung , Agudelo-Garcia Paula A. , Saldivar Joshua C. , Dolan Claire E. , Mora Maria E. , Nuovo Gerard J. , Cole Susan E. , Viapiano Mariano S.
Published: April 2023

PDF file - 388K, Fibulin-3 is highly upregulated in high-grade gliomas and associates with the mesenchymal phenotype
Supplementary Figure Legends 1-6 from Strain-Specific Variation in Murine Natural Killer Gene Complex Contributes to Differences in Immunosurveillance for Urethane-Induced Lung Cancer
Authors: Kreisel Daniel , Gelman Andrew E. , Higashikubo Ryuji , Lin Xue , Vikis Haris G. , White J. Michael , Toth Kelsey A. , Deshpande Charuhas , Carreno Beatriz M. , You Ming , Taffner Samantha M. , Yokoyama Wayne M. , Bui Jack D. , Schreiber Robert D. , Krupnick Alexander S.
Published: April 2023

PDF file - 33K
Supplementary Figure 6 from Strain-Specific Variation in Murine Natural Killer Gene Complex Contributes to Differences in Immunosurveillance for Urethane-Induced Lung Cancer
Authors: Kreisel Daniel , Gelman Andrew E. , Higashikubo Ryuji , Lin Xue , Vikis Haris G. , White J. Michael , Toth Kelsey A. , Deshpande Charuhas , Carreno Beatriz M. , You Ming , Taffner Samantha M. , Yokoyama Wayne M. , Bui Jack D. , Schreiber Robert D. , Krupnick Alexander S.
Published: April 2023

PDF file - 47K, SNP rs13459098 in the Pas-1 locus is of 129 origin in 129/SvEv.B6-NKC Rag2-/- mice
Supplementary Figure 2 from Opposing Roles for IL-23 and IL-12 in Maintaining Occult Cancer in an Equilibrium State
Authors: Teng Michele W. L. , Vesely Matthew D. , Duret Helene , McLaughlin Nicole , Towne Jennifer E. , Schreiber Robert D. , Smyth Mark J.
Published: April 2023

PDF file - 111K, Cancer:immune equilibrium in p53+/- mice
Supplementary Figure 1 from Opposing Roles for IL-23 and IL-12 in Maintaining Occult Cancer in an Equilibrium State
Authors: Teng Michele W. L. , Vesely Matthew D. , Duret Helene , McLaughlin Nicole , Towne Jennifer E. , Schreiber Robert D. , Smyth Mark J.
Published: April 2023

PDF file - 66K, Occult tumors persist in equilibrium
Supplementary Table 1 from BMP4 Administration Induces Differentiation of CD133+ Hepatic Cancer Stem Cells, Blocking Their Contributions to Hepatocellular Carcinoma
Authors: Zhang Lixing , Sun Hefen , Zhao Fangyu , Lu Ping , Ge Chao , Li Hong , Hou Helei , Yan Mingxia , Chen Taoyang , Jiang Guoping , Xie Haiyang , Cui Ying , Huang Xiaowu , Fan Jia , Yao Ming , Li Jinjun
Published: April 2023

PDF file - 82K, Antibodies used in this study
Supplementary Figures 1-6, Tables 1-4, Methods from Epithelial–Mesenchymal Transition Induced by TNF-α Requires NF-κB–Mediated Transcriptional Upregulation of Twist1
Authors: Li Chia-Wei , Xia Weiya , Huo Longfei , Lim Seung-Oe , Wu Yun , Hsu Jennifer L. , Chao Chi-Hong , Yamaguchi Hirohito , Yang Neng-Kai , Ding Qingqing , Wang Yan , Lai Yun-Ju , LaBaff Adam M. , Wu Ting-Jung , Lin Been-Ren , Yang Muh-Hwa , Hortobagyi Gabriel N. , Hung Mien-Chie
Published: April 2023

PDF file - 1.8MB
Supplementary Methods from BMP4 Administration Induces Differentiation of CD133+ Hepatic Cancer Stem Cells, Blocking Their Contributions to Hepatocellular Carcinoma
Authors: Zhang Lixing , Sun Hefen , Zhao Fangyu , Lu Ping , Ge Chao , Li Hong , Hou Helei , Yan Mingxia , Chen Taoyang , Jiang Guoping , Xie Haiyang , Cui Ying , Huang Xiaowu , Fan Jia , Yao Ming , Li Jinjun
Published: April 2023

PDF file - 93K
Supplementary Table 2 from Cancer Cells Cue the p53 Response of Cancer-Associated Fibroblasts to Cisplatin
Authors: Schmid Jens O. , Dong Meng , Haubeiss Silke , Friedel Godehard , Bode Sabine , Grabner Andreas , Ott German , Mürdter Thomas E. , Oren Moshe , Aulitzky Walter E. , van der Kuip Heiko
Published: April 2023

PDF file - 61K, Constitutive levels of p53, p21 and TUNEL positivity in CAFs
Supplementary Table 1 from Brachytherapy Using Injectable Seeds That Are Self-Assembled from Genetically Encoded Polypeptides In Situ
Authors: Liu Wenge , McDaniel Jonathan , Li Xinghai , Asai Daisuke , Quiroz Felipe Garcia , Schaal Jeffery , Park Ji Sun , Zalutsky Michael , Chilkoti Ashutosh
Published: April 2023

PDF file - 128K, The effect of the number of ELP tyrosine residues, ELP MW and concentration on retention radioactivity in FaDu tumor as a function of time post-injection of labeled ELP
Supplementary Table 1 from Cancer Cells Cue the p53 Response of Cancer-Associated Fibroblasts to Cisplatin
Authors: Schmid Jens O. , Dong Meng , Haubeiss Silke , Friedel Godehard , Bode Sabine , Grabner Andreas , Ott German , Mürdter Thomas E. , Oren Moshe , Aulitzky Walter E. , van der Kuip Heiko
Published: April 2023

PDF file - 86K, Patient characteristics and treatment regimens
Supplementary Figure 1 from Proinflammatory Characteristics of SMAC/DIABLO-Induced Cell Death in Antitumor Therapy
Authors: Emeagi Perpetua U. , Van Lint Sandra , Goyvaerts Cleo , Maenhout Sarah , Cauwels Anje , McNeish Iain A. , Bos Tomas , Heirman Carlo , Thielemans Kris , Aerts Joeri L. , Breckpot Karine
Published: April 2023

PDF file - 184K, The therapeutic effect of LV-tSMAC involves effector T-cells.
Supplementary Figure 5 from The Proinflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma
Authors: Wu Juan , Li Jiaqi , Salcedo Rosalba , Mivechi Nahid F. , Trinchieri Giorgio , Horuzsko Anatolij
Published: April 2023

PDF file - 7.2MB, The expression of TREM-1 in human liver KC
Supplementary Figure 3 from The Proinflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma
Authors: Wu Juan , Li Jiaqi , Salcedo Rosalba , Mivechi Nahid F. , Trinchieri Giorgio , Horuzsko Anatolij
Published: April 2023

PDF file - 2.5MB, Deletion of TREM-1 down regulates genes associated with DNA repair and genes involved in hepatocellular carcinoma development
Supplementary Figure 2 from The Proinflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma
Authors: Wu Juan , Li Jiaqi , Salcedo Rosalba , Mivechi Nahid F. , Trinchieri Giorgio , Horuzsko Anatolij
Published: April 2023

PDF file - 835K, TREM-1 expression on KC of WT mice increased after DEN administration
Supplementary Figure 5 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: April 2023

PDF - 419K, Activation of Kras concomitant with PTEN loss (PTENKO/Kras) results in endometrial tumors that invade the kidney parenchyma.
Supplementary Figure 2 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: April 2023

PDF - 188K, Biologic behavior of PTENKO tumors during and after cessation of progesterone therapy.
Supplementary Table 4 from Cisplatin Sensitivity Mediated by WEE1 and CHK1 Is Mediated by miR-155 and the miR-15 Family
Authors: Pouliot Lynn M. , Chen Yu-Chi , Bai Jennifer , Guha Rajarshi , Martin Scott E. , Gottesman Michael M. , Hall Matthew D.
Published: April 2023

XLs file - 164K, Results from kinome siRNA screen
Supplementary Table 3 from Cisplatin Sensitivity Mediated by WEE1 and CHK1 Is Mediated by miR-155 and the miR-15 Family
Authors: Pouliot Lynn M. , Chen Yu-Chi , Bai Jennifer , Guha Rajarshi , Martin Scott E. , Gottesman Michael M. , Hall Matthew D.
Published: April 2023

XLS file - 59K, Results from miRNA mimic screen
Supplementary Figure 1 from Progesterone Receptor Signaling in the Microenvironment of Endometrial Cancer Influences Its Response to Hormonal Therapy
Authors: Janzen Deanna M. , Rosales Miguel A. , Paik Daniel Y. , Lee Daniel S. , Smith Daniel A. , Witte Owen N. , Iruela-Arispe M. Luisa , Memarzadeh Sanaz
Published: April 2023

PDF - 250K, Histology of PTENKO tumors and hormone supplementation in treated mice.
Supplementary Methods, Figures 1-9, Tables 2-6 from EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes β-Catenin–Dependent Hepatocarcinogenesis
Authors: Cheng Alfred S.L. , Lau Suki S. , Chen Yangchao , Kondo Yutaka , Li May S. , Feng Hai , Ching Arthur K. , Cheung Kin F. , Wong Hoi K. , Tong Joanna H. , Jin Hongchuan , Choy Kwong W. , Yu Jun , To Ka F. , Wong Nathalie , Huang Tim H.-M. , Sung Joseph J.Y.
Published: April 2023

Supplementary Methods, Figures 1-9, Tables 2-6 from EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes β-Catenin–Dependent Hepatocarcinogenesis
Supplementary Table 4 from Hedgehog Signaling Blockade Delays Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein
Authors: Arzumanyan Alla , Sambandam Vaishnavi , Clayton Marcia M. , Choi Steve S. , Xie Guanhua , Diehl Anna Mae , Yu Dae-Yeul , Feitelson Mark A.
Published: April 2023

PDF file - 72K, HBx and Hh components in the liver of HBxTg
Supplementary Table 2 from Hedgehog Signaling Blockade Delays Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein
Authors: Arzumanyan Alla , Sambandam Vaishnavi , Clayton Marcia M. , Choi Steve S. , Xie Guanhua , Diehl Anna Mae , Yu Dae-Yeul , Feitelson Mark A.
Published: April 2023

PDF file - 67K, Summary of staining for HBx, Shh, Ihh, PTCH1 and Gli2 and correlation with HBx expression in clinical samples
Supplementary Figure Legends 1-5, Tables 1-4 from Intragenic ATM Methylation in Peripheral Blood DNA as a Biomarker of Breast Cancer Risk
Authors: Brennan Kevin , Garcia-Closas Montserrat , Orr Nick , Fletcher Olivia , Jones Michael , Ashworth Alan , Swerdlow Anthony , Thorne Heather , Riboli Elio , Vineis Paolo , Dorronsoro Miren , Clavel-Chapelon Francoise , Panico Salvatore , Onland-Moret N. Charlotte , Trichopoulos Dimitrios , Kaaks Rudolf , Khaw Kay-Tee , Brown Robert , Flanagan James M.
Published: April 2023

PDF file - 130K
Supplementary Table 1 from Hedgehog Signaling Blockade Delays Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein
Authors: Arzumanyan Alla , Sambandam Vaishnavi , Clayton Marcia M. , Choi Steve S. , Xie Guanhua , Diehl Anna Mae , Yu Dae-Yeul , Feitelson Mark A.
Published: April 2023

PDF file - 58K, qRT-PCR primers
Supplementary Table 2 from Cancer Stem Cell Vaccination Confers Significant Antitumor Immunity
Authors: Ning Ning , Pan Qin , Zheng Fang , Teitz-Tennenbaum Seagal , Egenti Martin , Yet Ji , Li Mu , Ginestier Christophe , Wicha Max S. , Moyer Jeffrey S. , Prince Mark E.P. , Xu Yingxin , Zhang Xiao-Lian , Huang Shiang , Chang Alfred E. , Li Qiao
Published: April 2023

PDF file - 57K
Supplementary Figures 1-2, Table 1 from Cancer Stem Cell Vaccination Confers Significant Antitumor Immunity
Authors: Ning Ning , Pan Qin , Zheng Fang , Teitz-Tennenbaum Seagal , Egenti Martin , Yet Ji , Li Mu , Ginestier Christophe , Wicha Max S. , Moyer Jeffrey S. , Prince Mark E.P. , Xu Yingxin , Zhang Xiao-Lian , Huang Shiang , Chang Alfred E. , Li Qiao
Published: April 2023

PDF file - 185K
Supplementary Figure 2 from Hedgehog Signaling Blockade Delays Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein
Authors: Arzumanyan Alla , Sambandam Vaishnavi , Clayton Marcia M. , Choi Steve S. , Xie Guanhua , Diehl Anna Mae , Yu Dae-Yeul , Feitelson Mark A.
Published: April 2023

PDF file - 649K
Supplementary Figure Legends 1-3 from Multiple Roles of p53-Related Pathways in Somatic Cell Reprogramming and Stem Cell Differentiation
Authors: Yi Lan , Lu Chiwei , Hu Wenwei , Sun Yvonne , Levine Arnold J.
Published: April 2023

PDF file - 65K
Supplementary Figure 2 from Multiple Roles of p53-Related Pathways in Somatic Cell Reprogramming and Stem Cell Differentiation
Authors: Yi Lan , Lu Chiwei , Hu Wenwei , Sun Yvonne , Levine Arnold J.
Published: April 2023

PDF file - 415K, Normal stem cells can be cultured under temperatures ranged from 32C to 39C and normal iPSC can be formed from MEF cells under these temperatures.
Supplementary Figure 2 from Metabolic Associations of Reduced Proliferation and Oxidative Stress in Advanced Breast Cancer
Authors: Jerby Livnat , Wolf Lior , Denkert Carsten , Stein Gideon Y. , Hilvo Mika , Oresic Matej , Geiger Tamar , Ruppin Eytan
Published: April 2023

PDF file, 427K, MPA example. An example of MPA computation based on a metabolic model and gene-expression or protein abundance measurements. Circular nodes represent metabolites, whereas diamond nodes represent enzymes. For enzymes, gray, red and green represent normal, significantly high and significantly low expression of the enzyme or enzyme-encoding genes, respectively. Similarly, for reactions, those that are predicted as active, inactive or undetermined are colored red, green, or gray, respectively. Solid edges represent metabolic reactions. Broken edges associate enzymes with the reactions they catalyze. The optimal solution obtained for a given sample with (B, D) or without (A, C) the additional constraint to activate the metabolic process of M9 production is shown. The score of the solution is the sum of reactions that are consistent with their expression state, which is what we aim to maximize. The MPA score of a given sample and a metabolic process is then the ratio between the optimal scores obtained with and without the process activity. As each sample has its unique expression profile, different MPA scores are obtained: The M9 production MPA score of sample 1 is smaller than that of sample 2, as its expression is less consistent with M9 production (i.e., enzymes E5 and E7 are lowly expressed).
Supplemenary Figure 4 from Metabolic Associations of Reduced Proliferation and Oxidative Stress in Advanced Breast Cancer
Authors: Jerby Livnat , Wolf Lior , Denkert Carsten , Stein Gideon Y. , Hilvo Mika , Oresic Matej , Geiger Tamar , Ruppin Eytan
Published: April 2023

PDF file, 40K, Intracellular ROS levels are reduced in metastatic BC cells. The distribution of superoxide levels in metastatic (blue) and non-metastatic (red) cell-lines.
Supplementary Figure 8 from Sef Downregulation by Ras Causes MEK1/2 to Become Aberrantly Nuclear Localized Leading to Polyploidy and Neoplastic Transformation
Authors: Duhamel Stéphanie , Hébert Josée , Gaboury Louis , Bouchard Amélie , Simon Ronald , Sauter Guido , Basik Mark , Meloche Sylvain
Published: April 2023

PDF file - 284K
Supplementary Tables 6 -7 from Dissection of T-cell Antigen Specificity in Human Melanoma
Authors: Andersen Rikke Sick , Thrue Charlotte Albæk , Junker Niels , Lyngaa Rikke , Donia Marco , Ellebæk Eva , Svane Inge Marie , Schumacher Ton N. , thor Straten Per , Hadrup Sine Reker
Published: April 2023

PDF file - 25K
Supplementary Figure 6 from Sef Downregulation by Ras Causes MEK1/2 to Become Aberrantly Nuclear Localized Leading to Polyploidy and Neoplastic Transformation
Authors: Duhamel Stéphanie , Hébert Josée , Gaboury Louis , Bouchard Amélie , Simon Ronald , Sauter Guido , Basik Mark , Meloche Sylvain
Published: April 2023

PDF file - 828K
Supplementary Figure 3 from Sef Downregulation by Ras Causes MEK1/2 to Become Aberrantly Nuclear Localized Leading to Polyploidy and Neoplastic Transformation
Authors: Duhamel Stéphanie , Hébert Josée , Gaboury Louis , Bouchard Amélie , Simon Ronald , Sauter Guido , Basik Mark , Meloche Sylvain
Published: April 2023

PDF file - 316K
Supplementary Figure Legends 1-3, Table Legends 1-7 from Dissection of T-cell Antigen Specificity in Human Melanoma
Authors: Andersen Rikke Sick , Thrue Charlotte Albæk , Junker Niels , Lyngaa Rikke , Donia Marco , Ellebæk Eva , Svane Inge Marie , Schumacher Ton N. , thor Straten Per , Hadrup Sine Reker
Published: April 2023

PDF file - 78K
Supplementary Figure 1 from Sef Downregulation by Ras Causes MEK1/2 to Become Aberrantly Nuclear Localized Leading to Polyploidy and Neoplastic Transformation
Authors: Duhamel Stéphanie , Hébert Josée , Gaboury Louis , Bouchard Amélie , Simon Ronald , Sauter Guido , Basik Mark , Meloche Sylvain
Published: April 2023

PDF file - 532K
Supplementary Tables 1-2 from ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells
Authors: Faget Julien , Bendriss-Vermare Nathalie , Gobert Michael , Durand Isabelle , Olive Daniel , Biota Cathy , Bachelot Thomas , Treilleux Isabelle , Goddard-Leon Sophie , Lavergne Emilie , Chabaud Sylvie , Blay Jean Yves , Caux Christophe , Ménétrier-Caux Christine
Published: April 2023

PDF file - 103K, Table S1: Clinical characteristic of the cohort of BT patients enrolled for TMA analysis (n=120) Table S2: clones of mAbs used for the multi-parametric flow cytometry analyses
Supplementary Figure 3 from 6-Bromoindirubin-3′-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells
Authors: Liu Lucy , Nam Sangkil , Tian Yan , Yang Fan , Wu Jun , Wang Yan , Scuto Anna , Polychronopoulos Panos , Magiatis Prokopios , Skaltsounis Leandros , Jove Richard
Published: April 2023

Supplementary Figure 3 from 6-Bromoindirubin-3′-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells
Supplementary Figures 1-6 from ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells
Authors: Faget Julien , Bendriss-Vermare Nathalie , Gobert Michael , Durand Isabelle , Olive Daniel , Biota Cathy , Bachelot Thomas , Treilleux Isabelle , Goddard-Leon Sophie , Lavergne Emilie , Chabaud Sylvie , Blay Jean Yves , Caux Christophe , Ménétrier-Caux Christine
Published: April 2023

PDF file - 296K, Figure S1: ICOS is mainly expressed by TA-Treg. Figure S2: pDC expanded Treg sustain suppressive activity. Figure S3: ICOS-L is highly expressed on R848-activated HD-pDC. Figure S4: ICOS blockade reduces Treg but not Tconv proliferation induced by pDC without impacting mDC/T cell activation. Figure S5: Strong IL-10 secretion in culture of BT single cell suspension. Figure S6: Correlation between TA-pDC and TA-Treg percentages in fresh primary BT and in retrospective IHC cohort
Supplementary Figure 1 from 6-Bromoindirubin-3′-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells
Authors: Liu Lucy , Nam Sangkil , Tian Yan , Yang Fan , Wu Jun , Wang Yan , Scuto Anna , Polychronopoulos Panos , Magiatis Prokopios , Skaltsounis Leandros , Jove Richard
Published: April 2023

Supplementary Figure 1 from 6-Bromoindirubin-3′-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells
Supplementary Table 1 from Densely Granulated Murine NK Cells Eradicate Large Solid Tumors
Authors: Liu Rebecca B. , Engels Boris , Arina Ainhoa , Schreiber Karin , Hyjek Elizabeth , Schietinger Andrea , Binder David C. , Butz Eric , Krausz Thomas , Rowley Donald A. , Jabri Bana , Schreiber Hans
Published: April 2023

PDF file - 55K
Supplementary Figure 4 from Tumor-Derived Chemokine CCL5 Enhances TGF-β–Mediated Killing of CD8+ T Cells in Colon Cancer by T-Regulatory Cells
Authors: Chang Li-Yuan , Lin Yung-Chang , Mahalingam Jayashri , Huang Ching-Tai , Chen Ten-Wen , Kang Chiao-Wen , Peng Hui-Min , Chu Yu-Yi , Chiang Jy-Ming , Dutta Avijit , Day Yuan-Ji , Chen Tse-Ching , Yeh Chau-Ting , Lin Chun-Yen
Published: April 2023

PDF file - 154K
Supplementary Figures 1-5 from Paracrine Hedgehog Signaling Drives Metabolic Changes in Hepatocellular Carcinoma
Authors: Chan Isaac S. , Guy Cynthia D. , Chen Yuping , Lu Jiuyi , Swiderska-Syn Marzena , Michelotti Gregory A. , Karaca Gamze , Xie Guanhua , Krüger Leandi , Syn Wing-Kin , Anderson Blair R. , Pereira Thiago A. , Choi Steve S. , Baldwin Albert S. , Diehl Anna Mae
Published: April 2023

PDF file - 127K, S1. Panc 10.05 cells do not generate functional Hh ligands. S2. Other malignant hepatoma lines can increase MF Hh and glycolytic activity. S3. Summary of glycolytic metabolism. S4. MF-derived lactate provides energy source for lipogenesis in other malignant hepatoma lines. S5. Schematic of alterations in hepatoma cells due to release of metabolic end products by glycolytic MF
Supplementary Methods, Figures 1 - 13 from DDB2 Suppresses Epithelial-to-Mesenchymal Transition in Colon Cancer
Authors: Roy Nilotpal , Bommi Prashant V. , Bhat Uppoor G. , Bhattacharjee Shaumick , Elangovan Indira , Li Jing , Patra Krushna C. , Kopanja Dragana , Blunier Adam , Benya Richard , Bagchi Srilata , Raychaudhuri Pradip
Published: April 2023

PDF file - 13093K, Supplementary Fig.1: Loss of DDB2 expression in human colon cancer. Supplementary Fig.2: Low magnification IHC data showing reduced expression of DDB2 in high grade colon cancer samples. Supplementary Fig.3: Depletion of DDB2 increases invasivness of colon cancer cells. Supplementary Fig.4: Polyclonal DDB2 knockdown colon cancer cells exhibit increased tumorigenicity Supplementary Fig.5: Polyclonal DDB2 knockdown colon cancer cells exhibit EMT Supplementary Fig.6: DDB2 knockdown colon cancer cells generate aggressive tumors in nude mice Supplementary Fig.7: Low magnification picture showing EMT in xenografted tumors Supplementary Fig.8: DDB2 expression blocks EMT induced by hypoxia and TGF-beta Supplementary Fig.9: Chromatin-IP using T7-antibody demonstrating interaction of T7-DDB2 with the VEGF, Snail and Zeb1 promoters. Supplementary Fig.10: Transcription factor binding sites in the promoter fragments bound by DDB2 Supplementary Fig.11: Western blot analyses for the DDB2-associated proteins and XPC in DDB2-depleted cells. Supplementary Fig.12: Experimental metastasis assay with polyclonal DDB2 knockdown cells. Supplementary Fig.13: Expression of DDB2 does not inhibit proliferation in SW620 cells.
Supplementary Figure 5 from Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
Authors: Diaconu Iulia , Cerullo Vincenzo , Hirvinen Mari L.M. , Escutenaire Sophie , Ugolini Matteo , Pesonen Saila K. , Bramante Simona , Parviainen Suvi , Kanerva Anna , Loskog Angelica S.I. , Eliopoulos Aristides G. , Pesonen Sari , Hemminki Akseli
Published: April 2023

PDF file - 120K, C57Bl/6 mice bearing B16-Ova tumors were injected intratumorally with the respective viruses as described in materials and methods. Lymph nodes, spleens and tumors were collected 8 days after first virus injection, smashed and cultured for 24 hours. Analysis of T-cell markers was performed by flow cytometry for CD3, CD4 and CD8 and plotted as mean +SEM. *, P<0.05.
Supplementary Methods from TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells
Authors: Weiss Michele B. , Abel Ethan V. , Mayberry Melanie M. , Basile Kevin J. , Berger Adam C. , Aplin Andrew E.
Published: April 2023

PDF file - 106K
Supplementary Figure 1 from Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus
Authors: Diaconu Iulia , Cerullo Vincenzo , Hirvinen Mari L.M. , Escutenaire Sophie , Ugolini Matteo , Pesonen Saila K. , Bramante Simona , Parviainen Suvi , Kanerva Anna , Loskog Angelica S.I. , Eliopoulos Aristides G. , Pesonen Sari , Hemminki Akseli
Published: April 2023

PDF file - 881K, (A) Oncolytic potency of Ad5/3-hTERT-E1A-hCD40L and (B) Ad5/3-hTERT-E1A on EJ (CD40+) and A549 (CD40-). Cell lines were infected with Ad5/3Luc1, Ad5/3-hTERT-E1A, Ad5/3-hTERT-E1A-hCD40L and Ad5/3-CMV-hCD40L and cell viability was measured by MTS assay The assay was stopped 7 days after infection and the data was plotted to compare efficacy on CD40+ versus CD40- cells; Ad5/3-hTERT-E1A-hCD40L was more effective than the positive control on the former while the opposite was true for the latter. . VP=viral particles. ***, P<0.001 (C) Cell monolayers of EJ and A549 cell lines were infected with 1000VP/cell with Ad5/3-hTERT-E1A-hCD40L and Ad5/3-hTERT-E1A and different concentrations of anti-CD40L antibody were added on the cells. Fourty-eight hours later the assay was stopped by measuring the mitochondrial activity through an MTS determination. Results are presented from triplicates relative to cells treated with virus alone. �g/ml=microgram/milliliter. (D) Cell cycle analysis. Cell monolayers infected with 100VP/cell for 2h were cultured for 48h and fixed in 70% ethanol at 40C overnight. Propidium Iodide staining was performed according to manufacturer instructions and cells were analyzed by FACS-Array. Cell counts of different cell cycle stages are presented relative to total number of cells.
Supplementary Table 1, Figures 1-10, Methods from An EGFR-ERK-SOX9 Signaling Cascade Links Urothelial Development and Regeneration to Cancer
Authors: Ling Shizhang , Chang Xiaofei , Schultz Luciana , Lee Thomas K. , Chaux Alcides , Marchionni Luigi , Netto George J. , Sidransky David , Berman David M.
Published: April 2023

Supplementary Table 1, Figures 1-10, Methods from An EGFR-ERK-SOX9 Signaling Cascade Links Urothelial Development and Regeneration to Cancer
Supplementary Figure 2 from miRNA-34 Prevents Cancer Initiation and Progression in a Therapeutically Resistant K-ras and p53-Induced Mouse Model of Lung Adenocarcinoma
Authors: Kasinski Andrea L. , Slack Frank J.
Published: April 2023

PDF file - 30K, In cells lines with mutant p53 serum withdrawal failed to induce miR-34 levels to the extent that miR-34 was induced in p53 wild-type cells.
Supplementary Figure 1 from Functional Interaction of Tumor Suppressor DLC1 and Caveolin-1 in Cancer Cells
Authors: Du Xiaoli , Qian Xiaolan , Papageorge Alex , Schetter Aaron J. , Vass William C. , Liu Xi , Braverman Richard , Robles Ana I. , Lowy Douglas R.
Published: April 2023

PDF file - 10.6MB, Mapping the CAV1 interaction to the START domain in the C-terminus of DLC1. The DLC1-Del (929-957) mutant is active in RhoGAP activity in transiently transfected H1299 cells and stably transfected H358 cells
Supplementary Figure Legends 1-4 from Loss of PPP2R2A Inhibits Homologous Recombination DNA Repair and Predicts Tumor Sensitivity to PARP Inhibition
Authors: Kalev Peter , Simicek Michal , Vazquez Iria , Munck Sebastian , Chen Liping , Soin Thomas , Danda Natasha , Chen Wen , Sablina Anna
Published: April 2023

PDF file - 88K
Supplementary Figure 4 from A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model
Authors: Gill Bartley J. , Gibbons Don L. , Roudsari Laila C. , Saik Jennifer E. , Rizvi Zain H. , Roybal Jonathon D. , Kurie Jonathan M. , West Jennifer L.
Published: April 2023

PDF file - 38K, Gelatin zymography shows MMP-2 and -9 expression relatively unchanged with TGF� treatment
Supplementary Figure 2 from A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model
Authors: Gill Bartley J. , Gibbons Don L. , Roudsari Laila C. , Saik Jennifer E. , Rizvi Zain H. , Roybal Jonathon D. , Kurie Jonathan M. , West Jennifer L.
Published: April 2023

PDF file - 20K, Histogram of sphere diameters of 344SQ encapsulated in 10% PEG-PQ / 3.5 mM PEG-RGDS matrix shows a relatively uniform population
Supplementary Methods from Macrophage Delivery of an Oncolytic Virus Abolishes Tumor Regrowth and Metastasis after Chemotherapy or Irradiation
Authors: Muthana Munitta , Rodrigues Samuel , Chen Yung-Yi , Welford Abigail , Hughes Russell , Tazzyman Simon , Essand Magnus , Morrow Fiona , Lewis Claire E.
Published: April 2023

PDF file - 115k, Methods describing the isolation, culture and transduction of human macrophages, generation of plasmids, the adenoviruses used, histological assessment of necrosis, and immunostaining techniques used
Supplementary Figure Legend from Dachshund Binds p53 to Block the Growth of Lung Adenocarcinoma Cells
Authors: Chen Ke , Wu Kongming , Cai Shaoxin , Zhang Wei , Zhou Jie , Wang Jing , Ertel Adam , Li Zhiping , Rui Hallgeir , Quong Andrew , Lisanti Michael P. , Tozeren Aydin , Tanes Ceylan , Addya Sankar , Gormley Michael , Wang Chenguang , McMahon Steven B. , Pestell Richard G.
Published: April 2023

PDF file - 72K
Supplementary Figure 3 from Macrophage Delivery of an Oncolytic Virus Abolishes Tumor Regrowth and Metastasis after Chemotherapy or Irradiation
Authors: Muthana Munitta , Rodrigues Samuel , Chen Yung-Yi , Welford Abigail , Hughes Russell , Tazzyman Simon , Essand Magnus , Morrow Fiona , Lewis Claire E.
Published: April 2023

PDF file - 68K, Presence of OV in lungs of mice bearing human prostate (LNCaP-LUC) tumors after docetaxel treatment or irradiation followed by macrophage delivery of OV
Supplementary Methods from Cetuximab Response of Lung Cancer–Derived EGF Receptor Mutants Is Associated with Asymmetric Dimerization
Authors: Cho Jeonghee , Chen Liang , Sangji Naveen , Okabe Takafumi , Yonesaka Kimio , Francis Joshua M. , Flavin Richard J. , Johnson William , Kwon Jihyun , Yu Soyoung , Greulich Heidi , Johnson Bruce E. , Eck Michael J. , Jänne Pasi A. , Wong Kwok-Kin , Meyerson Matthew
Published: April 2023

PDF file - 127K
Supplementary Figure 6 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
Authors: Kikuchi Koji , Narita Takeo , Pham Van T. , Iijima Junko , Hirota Kouji , Keka Islam Shamima , Okawa Katsuya , Hori Tetsuya , Fukagawa Tatsuo , Essers Jeroen , Kanaar Roland , Whitby Matthew C. , Sugasawa Kaoru , Taniguchi Yoshihito , Kitagawa Katsumi , Takeda Shunichi
Published: April 2023

PDF file - 151K, Schematic representation of XPF disruption in DT40 cells.
Supplementary Figure Legends from Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Authors: Abazeed Mohamed E. , Adams Drew J. , Hurov Kristen E. , Tamayo Pablo , Creighton Chad J. , Sonkin Dmitriy , Giacomelli Andrew O. , Du Charles , Fries Daniel F. , Wong Kwok-Kin , Mesirov Jill P. , Loeffler Jay S. , Schreiber Stuart L. , Hammerman Peter S. , Meyerson Matthew
Published: April 2023

PDF file, 76K.
Supplementary Figure 6 from Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Authors: Abazeed Mohamed E. , Adams Drew J. , Hurov Kristen E. , Tamayo Pablo , Creighton Chad J. , Sonkin Dmitriy , Giacomelli Andrew O. , Du Charles , Fries Daniel F. , Wong Kwok-Kin , Mesirov Jill P. , Loeffler Jay S. , Schreiber Stuart L. , Hammerman Peter S. , Meyerson Matthew
Published: April 2023

PDF file, 1002K, ssGSEA identifies gene sets that correlate with radiation resistance (left) and sensitivity (right). Top 50 gene sets are listed.
Supplementary Material from Coevolution of Solid Stress and Interstitial Fluid Pressure in Tumors During Progression: Implications for Vascular Collapse
Authors: Stylianopoulos Triantafyllos , Martin John D. , Snuderl Matija , Mpekris Fotios , Jain Saloni R. , Jain Rakesh K.
Published: April 2023

Supplementary Material - PDF file 594K, Supplementary Table S1. Values of the parameters calculated for the residual stretch ratio, �r1. Supplementary Table S2. Ratio of smaller to longer axis for peripheral arterioles and venules in different human tumor types. Supplementary Figure S1. Tumor opening and residual stretch ratio for a glioblastoma U87 ectopic tumor model grown on the flank of SCID mice. Supplementary Figure S2. The geometry of the domain and the boundary conditions employed. Supplementary Figure S3. Fitting of the model to the experimental growth data of E0771 tumors to derive the parameters a, �, and �max. Supplementary Figure S4.The Boundary conditions employed for the biphasic simulations. Supplementary Figure S5. Evolution of interstitial fluid pressure: Comparison of model predictions to experimentally derived data from Ref. 24.Supplementary Figure S6. Spatial profile of the total stress, defined as the sum of the fluid pressure with the average bulk solid stress, as a function of the parameter � and at day 10 of tumor growth.Supplementary Figure S7. Spatial distribution of interstitial fluid pressure for different values of the tumor hydraulic conducivity, Kt, keeping the conductivity of the normal tisuse, Kn=1x10-8 cm2/mmHg-s. Supplementary Figure S8. Radial stress distribution for two different shear moduli (20 kPa and 50 kPa) and for near incompressible (Poisson's ratio 0.5, top) and compressible tumors (Poisson's ratio 0.2, bottom). Supplementary Figure S9. Model predictions for incompressible vs. compressible mechanical behavior of tumors for different values of the Poisson's ratio, �. Supplementary Figure S10. Model predictions of tumor growth varying the parameters �, � and �max
Supplementary Figure 3 from Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Authors: Abazeed Mohamed E. , Adams Drew J. , Hurov Kristen E. , Tamayo Pablo , Creighton Chad J. , Sonkin Dmitriy , Giacomelli Andrew O. , Du Charles , Fries Daniel F. , Wong Kwok-Kin , Mesirov Jill P. , Loeffler Jay S. , Schreiber Stuart L. , Hammerman Peter S. , Meyerson Matthew
Published: April 2023

PDF file, 20K, High-throughput profiling of lung cancer cell lines.
Supplementary Figure 2 from Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Authors: Abazeed Mohamed E. , Adams Drew J. , Hurov Kristen E. , Tamayo Pablo , Creighton Chad J. , Sonkin Dmitriy , Giacomelli Andrew O. , Du Charles , Fries Daniel F. , Wong Kwok-Kin , Mesirov Jill P. , Loeffler Jay S. , Schreiber Stuart L. , Hammerman Peter S. , Meyerson Matthew
Published: April 2023

PDF file, 138K, High-throughput profiling of survival following exposure to �-radiation.
Supplementary Figure 3 from Notch1 Is Required for Kras-Induced Lung Adenocarcinoma and Controls Tumor Cell Survival via p53
Authors: Licciulli Silvia , Avila Jacqueline L. , Hanlon Linda , Troutman Scott , Cesaroni Matteo , Kota Smitha , Keith Brian , Simon M. Celeste , Puré Ellen , Radtke Fred , Capobianco Anthony J. , Kissil Joseph L.
Published: April 2023

PDF file, 346K, Notch1 ablation does not affect p53/MDM2 binding.
Supplementary Figure 3 from Loss of ARF Sensitizes Transgenic BRAFV600E Mice to UV-Induced Melanoma via Suppression of XPC
Authors: Luo Chi , Sheng Jinghao , Hu Miaofen G. , Haluska Frank G. , Cui Rutao , Xu Zhengping , Tsichlis Philip N. , Hu Guo-Fu , Hinds Philip W.
Published: April 2023

PDF file - 407K, DNA damage induced by BRAFV600E in human melanoma cells.
Supplementary Methods from OX40 Is a Potent Immune-Stimulating Target in Late-Stage Cancer Patients
Authors: Curti Brendan D. , Kovacsovics-Bankowski Magdalena , Morris Nicholas , Walker Edwin , Chisholm Lana , Floyd Kevin , Walker Joshua , Gonzalez Iliana , Meeuwsen Tanisha , Fox Bernard A. , Moudgil Tarsem , Miller William , Haley Daniel , Coffey Todd , Fisher Brenda , Delanty-Miller Laurie , Rymarchyk Nicole , Kelly Tracy , Crocenzi Todd , Bernstein Eric , Sanborn Rachel , Urba Walter J. , Weinberg Andrew D.
Published: April 2023

PDF file - 68K, Details clinical trial, flow cytometry and monkey experiments referred to in the manuscript.