bluuebunny/crossref_metadata_2025 huggingface dataset:
Social Specific Image: Format of Methodology and Auditing
Authors: Shavardova Elena Yu. , Yarmak Olga V.
Published: May 2021

The modern period of demand for image-logical knowledge allows raising questions not only about image-enlightenment and image-education, when information and telecommunication technologies become the determining factors in the development of society, but also about the peculiarities of teaching image-logical knowledge in higher educational institutions. At this stage, there is also the need to introduce the scientific and applied direction of the discipline “Imageologyˮ, as a component of social education, into the system of training specialists for a wide range of professions in the “person-to-personˮ sphere. The article explores a number of innovative approaches to teaching a special educational course “Imageologyˮ for students of humanitarian and social profiles. The article contains an analysis of scientific studies of the main methodological principles, tasks and parameters of the development of imageology as a practice-oriented sociological direction in the context of the training of Masters and specialists, sociologists, psychologists, journalists, advertising and public relations specialists. The authors identified the most important ways and directions for the formation of the sociology of the image, determined the subject and purpose of the discipline. For seminars and practical classes, as well as for students 'independent work, specialized scientific topics, an original image analysis questionnaire scheme are offered, and scenarios of specific events and actions in image creation are modeled for the development of students' professional and creative abilities.
The Phenomenon of Loneliness Among Young People
Authors: Lokоva Mariana Yu. , Khanova Marina N. , Zakhokhova Madina R.
Published: May 2021

In the context of globalization and informatization, there is a replacement of real communication with virtual, a loss of the value of live communication, respectively, there is social alienation and loneliness. The speed of exchange of messages and information is so high that people do not have time to develop their personal point of view, to individualize. In this regard, the questions are becoming more and more relevant: what is loneliness and whether it is possible to consider loneliness only as a negative phenomenon, or, loneliness is, on the contrary, a resource, i.e., an opportunity for personal development. The article discusses the issues of understanding the phenomenon of loneliness, its transformation in the modern world and predicting the impact on the world of the future, as well as whether there is a connection between loneliness and Internet addiction. The article analyzes the socio-philosophical aspect of youth loneliness and the totality of their social and personal determinations.
Formation of Professional Culture in Higher Education: Experience and Problems
Authors: Parshina Anna A. , Korolev Vladimir K.
Published: May 2021

The subject of the article is the formation of professional culture of students; it is considered in order to improve the work on its formation in the educational process at the University, in particular-in RIPB-on the material of training economists, lawyers and customs officers. The authors describe professional culture as a set of special knowledge and practical skills of a person as an “employeeˮ, implemented in a specific type of socially significant work, emphasize that it is based on the universal values of a professional as a «person». Therefore, the formation of professional culture is inseparable from the socio-humanitarian development of students, carried out in the course of studying the relevant disciplines. According to the authors, any professional culture has its own organization (in our case - University), which is based on a particular professional activity (in particular, University training), while it embodies a Form that is subject to “fillingˮ with the specific Content of various activities as socially institutionalized pro-fessions. As conclusions, the following problems are substantiated: introduction of a special course “Professional cultureˮ; overcoming “departmentalˮ disciplinarity in the study of socio-humanitarian and professional dis-ciplines; improving the quality of “formalˮ training of students in the conditions of digitalization and comput-erization; development of a culture of extracurricular forms of professional work.
O Processo de Tomada de Decisão Empreendedora na Internacionalização: Estudos de Caso com Novas Empresas de Base Tecnológica
Authors: Jardim Micael Daher , Dib Luís Antônio
Published: May 2021

Objetivo: Compreender o processo cognitivo do empreendedor ao buscar a internacionalização de sua pequena ou média empresa de base tecnológica.Método: Pesquisa bibliográfica, quatro estudos de caso, com empresas de base tecnológica de pequeno ou médio porte que já se internacionalizaram ou estão em vias de se internacionalizar incluindo entrevista com empreendedores e análise de documentação e informações públicas sobre a empresa.Principais resultados: Percebeu-se que os empreendedores não utilizam apenas uma lógica de tomada de decisão, mas as duas já descritas na literatura (Effectuation e Causation, segundo Sarasvathy, 2008) de forma cíclica e em três atividades diferentes e complementares: planejamento, execução e improviso.Relevância/originalidade: É proposto um novo modelo apresentado de forma esquemática, ilustrado pelos estudos de caso e aprofundado na conclusão do artigo.Contribuições teóricas/metodológicas:  A principal contribuição, além do modelo, é a indicação de qual critério oriundo da literatura contribui para que a tomada de decisão empreendedora siga as lógicas de Causation ou de Effectuation. Tal compilação é inédita na literatura de Negócios Internacionais.
Effect of Wrapping Materials and Storage Time on Shelf Life of Tuberose (Polianthes tuberosa L.)
Authors: . Happy , Chahal Devender , Devi Sarita , Malik Arvind , Kumar Suresh
Published: May 2021

Background: The use of wrapping material during storage of cut flowers creates a modified atmosphere which reduces flower metabolism during storage, thereby slowing carbohydrate consumption as respiratory substrate. The main problem related to dry storage is moisture loss or desiccation. Keeping in view the above aspects, the present study was conducted to enhance the shelf life of tuberose. Methods: The experiment was carried out at Post-Harvest Laboratory of Department of Horticulture, COA, CCS HAU, Hisar during the cropping season (March to September) of year 2019. It was laid out in CRD (factorial) with three replications and twenty-four treatment combinations, comprising of six wrapping materials (newspaper, butter paper, chart sheet, low density polyethylene of 100µ, high density polyethylene of 200µ and control as without wrapping) and four storage time (1, 4, 7 and 10 days), were tested. After harvesting, cut spikes were wrapped in wrapping materials and kept in cold-store at low temperature (less than 5°C), thereafter cut spikes were placed in vase solution (4% sucrose plus 300 ppm 8-HQC) for recording observations on floral parameters. Result: Among different wrapping materials, the butter paper wrapped cut spikes observed better in most of the parameters followed by LDPE (100µ) wrapped cut spikes. Among the storage time, storage of cut spikes for 1 day observed better in most of the parameters except time taken up to opening of first pair of florets and total post-harvest life. Overall, butter paper wrapped cut spikes stored for 1 day performed better in term of floret diameter (46.73 mm), floret length (56.10 mm), floret longevity (2.89 days), appearance (3.70/5.0 scale), florets opened at a time (32.30%), total opened florets (54.32%), marketable vase life (6.53 days), total vase life (11.17 days), weight loss (17.08%) and solution consumed (135.33 ml) by the spikes. However, the cut spikes wrapped in butter paper stored for 10 days were found better with early opening of first pair of florets (0.95 days) and maximum post-harvest life (20.10 days).
The Effect of Packaging Methods on the Shelf-life of Iron Fortified Mozzarella Cheese
Authors: Raquib M. , Borpuzari T. , Hazarika M. , Laskar S.K. , Saikia G.K. , Hazarika R.A.
Published: May 2021

Background: The present study was undertaken to study the effect of different packaging methods on the shelf-life of iron fortified mozzarella cheese prepared from cow milk, goat milk and mixed milk using kiwi fruit extract. Methods: Mozzarella cheese samples were packed both aerobically and under vacuum packaging condition and microbiological load (Total viable count, Escherichia coli, Salmonella, Shigella, Staphylococcus aureus, yeast and moulds and spores count) were monitored throughout the storage period in order to determine its shelf-life. Result: The total viable count (TVC) increased gradually from 0 day till 15 days of refrigerated storage for all the samples of iron fortified mozzarella cheese under both aerobic and vacuum packaging conditions irrespective of the types of milk and enzymes used. Under aerobic packaging condition, highest total viable count was observed for goat’s milk sample in both control and treatment groups all throughout the storage period. Mixed milk iron fortified mozzarella cheese exhibited least count in both the groups. The TVC of all the cheese samples were higher in aerobic packaging compared to vacuum packaging condition. The shelf-life or best before use of the product could judged as 15d from the date of manufacturing.
Multivariate Analysis of Quantitative Traits in Field Pea (Pisum sativum var. arvense)
Authors: Pratap Vijay , Sharma Vijay , Kumar Hitesh , . Kamaluddin , Shukla Gaurav , Kumar Mukul
Published: May 2021

Background: Field pea is one of the important cool season grain legume crops cultivated in India. In this investigation, experimental material i.e. eighty germplasm lines of field pea with four checks (IPF 4-9, Adarsh, Ambika and IPFD 10-12) were evaluated to determine the estimates of genetic diversity in the test genotypes. Methods: The data were recorded on thirteen quantitative characters for the study of genetic diversity. The mean data of each characters were subjected to cluster analysis by using D2 Mahalanobis clustering method. The principle component analysis (PCA) for measuring genetic divergence was done by XLSTAT and R 4.0 statistical package. Result: Eighty-four germplasms including checks were categorized into five distinct clusters, indicates the occurrence of high genetic diversity in the evaluated set of germplasm. Between cluster III and IV highest inter-cluster distance was observed, indicates the maximum diversity among genotypes of these clusters. Considerable differences were observed for cluster mean among different distinct clusters for all the thirteen characters. The hybridization programme involving genotypes from cluster III and cluster IV may be used to isolate suitable segregants. Principal component analysis grouped different traits under study into thirteen principal components (PCs) in which only five PCs with eigen value greater than 1 accounted 70.97% of total variation present in genotypes. The traits falling to these five PCs may be given due importance in field pea improvement programmes.
MERSBE - MERCADO DE RUÍDOS E SONS PARA O BEM-ESTAR: Modulações da Escuta e Cultura Aural Contemporânea
Authors: Pereira Vinícius Andrade
Published: May 2021

O presente artigo explora um mercado sonoro único: o MERSBE – Mercado de Ruídos e Sons para o Bem-Estar. Tal mercado se caracteriza por apresentar propostas ruidosas com fins diversos, tais como o aprimoramento da memória e da qualidade do sono, aumento da capacidade de concentração, curas físicas e psíquicas, dentre outras, sempre comprometidas com o bemestar. A emergência do MERSBE revela, ainda, como a cultura contemporânea estabelece novos modos de se relacionar com os ruídos, invertendo o que parecia ser a lógica dos seus usos até há pouco tempo. De uma posição provocadora e contestatória - como no caso do Manifesto Futurista de Russolo, na música concreta, ou ainda em músicos como E. Varese e J. Cage, até o movimento punk e o noise japonês – os ruídos parecem, agora, servir a mercados globais, sendo acolhidos e cultivados como experiências positivas e dóceis. Como isso pode afetar a cultura aural contemporânea? Essa é a questão central desse artigo, que foi elaborado a partir de uma imersão em sites de redes sociais, como o Youtube, para a observação dos produtos sônicos analisados. Como referência teórica principal estão os Estudos de Som e autores que trabalham com as materialidades da comunicação, principalmente. Como resultados finais, o artigo aponta alguns fatores que já podem ser entrevistos como partícipes relevantes, na modulação da escuta de ruídos na cultura aural contemporânea.
Perception of Emotions and Cultural Distance Among International Students in Russia
Authors: Berrios Callejas Sonia A.
Published: May 2021

The accurate perception of culture-specific emotions of the people living in the host country, may be the most significant, and yet the most underestimated challenge for the international students in the process of adjusting to a new culture. The latest report of the Institute of International Education (IIE) about Russia, confirmed that, in the year 2020, around 353,000 international students are currently studying in the Russian Federation. The studies of van de Vijver in 2007 and 2009 have confirmed that the foreign students from former Soviet republics or former USSR countries (students from post-soviet states, not including Russia: Armenia, Azerbaijan, Belarus, Estonia, Georgia, Kazakhstan, Kyrgyzstan, Latvia, Lithuania, Moldova, Tajikistan, Turkmenistan, Ukraine and Uzbekistan) have lower degrees of perceived cultural distance with Russian culture, this can be explained by the fact that the students from former Soviet republics can speak Russian language fluently, and share religion and traditions with Russian culture. Consequently, the group of students from former USSR countries adapt better to Russia in comparation to the rest of international students. The results of our study in 2020, revealed that the perception of Russian culture-specific emotions among international students studying in the Russian Federation, is significantly predicted by the similarity between the culture of the international students living in Russia and the culture of Russian society. Moreover, our study confirmed that the group of students from former Soviet republics, or former USSR countries, perceived more similarities with Russian national culture; therefore, this result is consistent with the findings of the aforementioned studies of van de Vijver in 2007 and 2009. Thus, we can consider that the accurate recognition of Russian culture-specific emotions and the perceived similarities to Russian cultural standards, may be very significant for the international students studying in the Russian Federation, especially for their process of adjusting to Russian culture. Nevertheless, further research on this topic is needed.
On Legal Possibilities of Limiting Labor Migration within the Eurasian Economic Union: from Theory to Practice in Conditions of the COVID-19 Pandemic
Authors: Ivanov Dmitry V. , Levina Maria M.
Published: May 2021

The article is focused on the study of the legal possibilities of restricting labor migration flows within the framework of the Eurasian Economic Union (hereinafter – the EAEU, the Union). Taking into account the fact that the deepening of the economic integration between the EAEU’s member states (Armenia, Belarus, Kazakhstan, Kyrgyzstan and Russia) also largely depends on the efficient operation of the common labor market, it is especially relevant to ensure that legislative measures aimed at overcoming the negative consequences of the spread of a new coronavirus infection (COVID-19) fully correspond to the legal conditions for its development. The analysis carried out by the authors is based on a two-level system of studying the relevant legal norms – the level of international treaties and acts that constitute the law of the EAEU, and the level of national legislation of the Union member states. Although Section XXVI of the Treaty on the EAEU secures the freedom of movement of labor in the Eurasian space, the norms of this agreement, however, provide for the possibility of introducing certain restrictions on admission to the common labor market of citizens of the Union member states. In view of the fact that the relevant provisions of the EAEU law were widely tested in practice in 2020, the authors consider them through the prism of those anti-crisis and stabilization measures that have been taken by the states in connection with the threat of further spread of the new infection. At the same time, the imposed restrictions are to be examined in this work with the use of a comparative method of analysis: to what extent the regulation of the legal status of citizens of the Union member states in the territories of the host state has been changed in the national legislation of the Union countries. In the final part of the present article, the authors assess the legal compliance of the taken measures with the statutory goals of the EAEU, as well as review the current problems in the further development of an agreed and effective system for regulating migration processes, given the actions of states to prevent the spread of coronavirus infection.
Mass Migration and COVID-19 Epidemic in China During Spring Festival 2020
Authors: Boyarkina Anna V.
Published: May 2021

The global pandemic of the coronavirus infection COVID-19, which broke out in early 2020, has become a serious test for all of humanity and for China. The epidemic was accompanied by mass migration in the most populous country in the world ahead of the Chunjie Spring Festival (春节) on January 25, 2020. This further aggravated the situation. Scientists from China and other countries have conducted large-scale studies using Big Data to establish the relationship between the number of migrants and the total number of confirmed cases. This article aims to determine the contribution of these works, carried out using methods such as scale-invariant network, correlation analysis and Bayesian approach, and provide recommendations for further research on the implementation of scientific innovations to solve migration problems in a pandemic. The paper provides an overview of the main ideas of foreign scientists, examines the research methods they used, identifies their advantages and disadvantages, presents recommendations for further research on the role of migration in the spread of infectious diseases. The novelty lies in the review of similar methods that were not previously used in similar studies by Russian demographers. In particular, the use of Big Data allowed scientists to establish that the population that left Wuhan was the main source of transmission of the virus to other cities and regions of China. The scale-invariant network method allowed for an analysis of the temporal and spatial distribution of cases, which shows that in Hubei province, where the largest number of cases and deaths were recorded, their growth slowed down rapidly. In other “hot spots”, on the contrary, the number of cases was initially low, but the increase in the number of cases at the beginning of the epidemic continued. The application of the Bayesian approach in research allowed scientists to prove that more attention should be paid to eliminating the negative socio-economic consequences of the epidemic among migrants as a particularly vulnerable group and to provide them with timely medical assistance, including psychological.
THE IMPACT OF CORPORATE GOVERNANCE STRUCTURE ON THE EXTERNAL AUDIT FEE IN SHARIA SHARES
Authors: Rasid Abdul
Published: May 2021

Introduction: This study aims to determine the impact of corporate governance structures on external fees in sharia stocks that are consistently listed in JII in 2013-2018.Methods: The number of samples in this study recorded 12 consistent sharia stocks listed in the years 2013-2018. This study uses a quantitative approach with panel data analysis method.Results: The results show that the average size of the board of commissioners is six to seven people, the average size of the board of directors is seven to eight people, the average size of the audit committees is three to four people, and the average size of the internal audit is fifteen to sixteen people. The hypothesis test shows that variables which have a significant impact on the audit fee are the size of the board of commissioners and the internal audit. Meanwhile, the size of the board of directors and the audit committees do not have a positive impact on audit fees.Conclusion and suggestion: Companies use more funding from debt than their own capital. Judging from the liquidity ratio, it shows that the company is in a liquid state, which is very capable of fulfilling obligations or debts that must be immediately paid by the company.
DETERMINANTS OF FEMALE WORKERS ON ECONOMIC GROWTH
Authors: Azizia Mohammad Ilham
Published: May 2021

Introduction: This study aims to find out what influences the Provincial Economic Growth in the Java Island if seen from female workers through the some variables, namely life expectancy of female, female's income contributions, and female as professionals.Methods: In this study using secondary data for 8 years from 2011 - 2018. The data analysis method used in this study is panel data regression analysis method. There are independent variables consisting of female's life expectancy, female's income contribution, and female as professionals. While the dependent variable is economic growth.Results: Based on the results of this study, it can be concluded that life expectancy has no significant effect on economic growth. The contribution of female's income has a significant effect on economic growth. Female as professionals has an insignificant effect on economic growth.Conclusion and suggestion: The central or regional government, the ministry of manpower and the ministry of female's empowerment and child protection or related institution to conduct training and human resource development for female by means of development activities in creating employment expansion, improving the quality of productive workforce and increasing the welfare of the workforce.
The Cost of Energy-Efficiency in Digital Hardware: The Trade-off between Energy Dissipation, Energy-Delay Product and Reliability in Electronic and Magnetic Binary Switches
Authors: Rahman Rahnuma , Bandyopadhyay Supriyo
Published: May 2021

Binary switches, which are the primitive units of all digital computing and information processing hardware, are usually benchmarked on the basis of their ‘energy-delay product’ which is the product of the energy dissipated in completing the switching action and the time it takes to complete that action. The lower the energy-delay product, the better the switch (supposedly). This approach ignores the fact that lower energy dissipation and faster switching usually come at the cost of poorer reliability (i. e. higher switching error rate) and hence the energy-delay product alone cannot be a good metric for benchmarking switches. Here, we show the trade-off between energy dissipation, energy-delay product and error-probability, for both an electronic switch (a metal oxide semiconductor field effect transistor) and a magnetic switch (a magnetic tunnel junction switched with spin transfer torque). As expected, reducing energy dissipation and/or energy-delay-product generally results in increased switching error probability and reduced reliability.
The Effect of Street Orientation on Outdoor Thermal Comfort in a Cold Mountainous Climate
Authors: Delpak Narges , Sajadzadeh Hassan , Hasanpourfard Saide , Aram Farshid
Published: May 2021

Lack of due attention to the orientation of streets and establishment of urban blocks without regard for climatic characteristics and conditions of the environment have an adverse effect on thermal comfort in open urban spaces. Construction of new settlements without taking into account climatic requirements undermines thermal comfort for pedestrians and other users, especially in cold regions. Considering the coldness of the region under study and the significance of the orientation of streets in absorbing radiation and providing heat to outdoor urban spaces, this study investigates the effect of the orientation of streets on microclimatic comfort in one of the residential towns of Hamadan City in Iran. For this purpose, microclimate simulation was performed using ENVI-met software. A residential block with four different orientations (the most common orientations of its surrounding buildings) were simulated in the coldest day of winter and the hottest day of summer. The results suggest that streets have different thermal behavior in different orientations. Orientation affects mean radiant temperature (Tmrt), the duration of exposure to direct sunlight, wind speed, and physiological equivalent temperature (PET), which are all important factors in thermal comfort. Based on these findings, north-south streets in Hamedan receive more radiant temperature during winter compared to other simulated orientations and provide more desirable thermal comfort. The average PET value on a winter day at a point on the north-south passage was 4.5-8 °C warmer than other orientations. In summer, streets with intercardinal orientations (i.e., northeast-southwest and northwest-southeast) provided the lowest PET (about 2 °C cooler than other orientations) and better thermal comfort
Management of Posidonia Oceanica Leaf Litter in Calabrian Sandy Beaches (Southern Italy).
Authors: Cantasano Nicola
Published: May 2021

The wracks of Posidonia oceanica leaves on the sandy beaches of Calabrian region could be one of the most important defence against erosion processes. The management of Posidonia oceanica leaf litter in Italy has been realized through the mechanical removal and the transport in dumping areas of the beach-cast material. This solution, apparently simple and fast, produces a net loss of sediments from the sandy beaches and, therefore, a deficit in the sedimentary budget of coastline leading the coastal system to possible shore erosions. Instead, it could be better to keep these vegetable deposits on the place so to warrant a positive sedimentary budget and the tourist value of the regional beaches improving coastal tourism in the seaside resorts with bathing vocation.
Crushing of Double-Walled Corrugated Board and Its Influence on the Load Capacity of Various Boxes
Authors: Gajewski Tomasz , Garbowski Tomasz , Staszak Natalia , Kuca Małgorzata
Published: May 2021

As long as the non-contact digital printing is not a common standard in the corrugated packaging industry, corrugated board crushing is a real issue that affects the load capacity of the boxes. Crushing mainly occurs during the converting of corrugated board (e.g. analog flexographic printing or laminating) and is a process that cannot be avoided. However, as show in this study, it can be controlled. In this work, extended laboratory tests were carried out on the crushing of double-walled corrugated board. The influence of fully controlled crushing (with a precision: ±10 μm) in the range from 10 to 70 % on different laboratory measurements was checked. Most of the typical mechanical tests were performed e.g. edge crush test, four-point bending test, shear stiffness test, torsional stiffness test, etc. on reference and crushed specimens. The residual thickness reduction of the crushed samples was also controlled. All empirical observations and performed measurements were the basis for building an analytical model of crushed corrugated board. The proven and verified model was then used to study the crushing effect of the selected corrugated board on the efficiency of simple packages with various dimensions.
Fungal Diversity and Aflatoxins in Cereals and Cassava-Based Foods From Ondo State, Nigeria
Authors: Ekpakpale Daniella O. , Kraak Bart , Meijer Martin , Ayeni Kolawole I. , Houbraken Jos , Ezekiel Chibundu N.
Published: May 2021

Cereals and cassava-based foods serve as major dietary sources for several households in Nigeria. However, these foods are highly prone to contamination by moulds and aflatoxins owing to poor storage and vending practices. We therefore studied the fungal diversity of maize, cassava-based flour (pupuru) and rice vended in markets from Ondo state, Nigeria, and assessed the aflatoxin levels of these using Enzyme-Linked Immunosorbent Assay. Fungi were detected in 93 (88 %) of the 106 food samples. Molecular analysis of 65 representative isolates revealed 26 species belonging to 5 genera: Aspergillus (80.9 %), Penicillium (15.4 %) and Talaromyces (1.9 %) in the Ascomycota; Syncephalastrum (1.2 %) and Lichtheimia (0.6%) in Mucoromycota. Aspergillus flavus was the predominant species in the food samples. Aflatoxins were found in 98 % of the 42 representative food samples and about one half (49.8 %) exceeded the 10 μg/kg threshold adopted in Nigeria for total aflatoxins. Integrated mitigation options, including at post-harvest stages, are suggested to ensure consumer safety.
Mold Detection on Food Surfaces Using YOLOv5
Authors: Jubayer Md. F. , Soeb Md. J. A. , Paul Mitun K. , Barua Pranta , Kayshar Md. S. , Rahman Md. M. , Islam Md. A.
Published: May 2021

The study aimed to identify different molds that grow on various food surfaces. As a result, we conducted a case study for the detection of mold on food surfaces based on the “you only look once (YOLO) v5” principle. In this context, a dataset of 2050 food images with mold growing on their surfaces was created. The dataset was trained using the pre-trained YOLOv5 algorithm. In comparison to YOLOv3 and YOLOv4, this current YOLOv5 model had better precision, recall, and average precision (AP), which were 98.10%, 100%, and 99.60%, respectively. The YOLOv5 algorithm was used for the first time in this study to detect mold on food surfaces. In conclusion, the proposed model successfully recognizes any kind of mold present on the food surface. Using YOLOv5, we are currently conducting research to identify the specific species of the detected mold.
Reducing Stress, Anxiety, and Depression for NICU Parents
Authors: Patton Amy , Dunavan Kylie , Key Kyla , Takahashi Steffani , Tenner Kathryn , Wilson Megan
Published: May 2021

This project aims to appraise evidence of the effectiveness of various practices on reducing stress, anxiety, and depression among parents of infants in the neonatal intensive care unit (NICU). The project contains six research articles from both national and international journals. Study designs include one meta-analysis, one randomized controlled trial, one small scale randomized controlled trial, one prospective phase lag cohort study, on pretest-posttest study, and one mixed-methods pretest-posttest study. Recommendations for effective interventions were based on best evidence discovered through quality appraisal and study outcomes. All interventions, except for educational programs and Kangaroo Care, resulted in a statistically significant reduction of either stress, anxiety, and/ or depression. Family centered care and mindfulness-based intervention reduced all barriers of interest. There is strong and high-quality evidence for the effect of Cognitive Behavioral Therapy on depression, moderate evidence for the effect of activity-based group therapy on anxiety, and promising evidence for the effect of HUG Your Baby on stress.
Quantitative Multiparameter Prediction of Fractured Tight Sandstone Reservoirs: A Case Study of the Yanchang Formation of the Ordos Basin, Central China
Authors: Liu Jingshou , Ding Wenlong , Yang Haimeng , Liu Yang
Published: May 2021

Fractured reservoirs account for more than one-half of the global oil and gas output and thus play a pivotal role in the world’s energy structure. Under diagenesis, rocks become dense, and tectonic fractures easily form under subsequent tectonic movement. These tectonic fractures are the main seepage conduits of tight sandstone reservoirs and are important determinants of whether a tight sandstone reservoir can have high, stable oil and gas production. The influence of multistage tectonic movement has led to well-developed fractures in the Ordos Basin in central China. In the process of reservoir development, the effective stress on the fracture surface increases because of the decrease in pore pressure, and the fracture aperture, porosity, and permeability also change accordingly. Therefore, modeling of the dual porosity and dual permeability of fractured reservoirs requires a dynamic 4D modeling process related to time. In this paper, we propose a 4D modeling method of dual porosity and dual permeability in fractured tight sandstone reservoirs. First, the porosity and permeability distribution of the reservoir matrix are established based on reservoir modeling. Based on geomechanical modeling, the density and occurrence of natural fractures are predicted by the paleostress field. The in-situ stress field is used to analyze the fracture aperture, and the variation in the fracture aperture during the development process is analyzed along with the variation in the in-situ stress in the development process to realize 4D modeling of the porosity and permeability of fractured reservoirs. The total porosity of the fracture is 0 to 8 × 10−3%, and the principal value of the planar permeability of the fracture is 0 to 3 × 10−3 µm2; the principal value of the fracture permeability is concentrated in the direction of 65 to 70° east-northeast. The simulated fracture porosity stress sensitivity index is distributed between 0 and 0.2, and the fracture permeability stress sensitivity index is distributed between 0 and 0.4. The Young’s modulus of the rock, in-situ stress parameters, and sound velocity in the rock are important factors affecting the fracture stress sensitivity.
Broadband model-based optoacoustic microscopy enables deep-tissue imaging beyond the acoustic diffraction limit
Authors: Li Weiye , Hofmann Urs Alexander Tassilo , Rebling Johannes , Zhou Quanyu , Chen Zhenyue , Özbek Ali , Gong Yuxiang , Razanksy Daniel , Dean-Ben Xose Luis
Published: May 2021

Optoacoustic microscopy (OAM) retrieves anatomical and functional contrast in vivo at depths not resolvable with optical microscopy. Recent progress on reconstruction algorithms have further advanced its imaging performance to provide high lateral resolution ultimately limited by acoustic diffraction. In this work, we suggest a new broadband model-based OAM (MB-OAM) framework efficiently exploiting scanning symmetries for an enhanced performance. By capitalizing on the large detection bandwidth of a spherical polyvinylidene difluoride (PVDF) film while accurately accounting for its spatial impulse response, the new approach significantly outperforms standard OAM implementations in terms of contrast and resolution, as validated by functional in vivo experiments in mice and human volunteers. Furthermore, L1-norm regularization enabled resolving structures separated by less than the theoretical diffraction-limited resolution. This unique label-free angiographic performance demonstrates the general applicability of MB-OAM as a super-resolution deep-tissue imaging method capable of breaking through the limits imposed by acoustic diffraction.
2-Day Versus 7-Day Course of Levofloxacin in Acute COPD Exacerbation
Authors: Messous Selma , Trabelsi Imen , Msolli Mohamed Amine , Sekma Adel , Touati Maha , Boukadida Lotfi , Ali Khaoula Bel Haj , Abdelghani Ahmed , Daya Yosra Ben , Razgallah Rabie , Grissa Mohamed Habib , Beltaief Kaouthar , Mezgar Zied , Methammem Mehdi , Belghith Asma , Bouida Wahid , Boukef Riadh , Boubaker Hamdi , Nouira Semir
Published: May 2021

Introduction: Duration of antibiotic treatment in acute exacerbation of COPD (AECOPD) is most commonly based on expert opinion. Typical administration periods range from 5 to 7 days. A 2-day course with levofloxacin was not previously assessed. We performed a randomized clinical trial to evaluate the efficacy of 2-day versus 7-day treatment with levofloxacin in patients with AECOPD.Methods: Patients with AECOPD were randomized to receive levofloxacin for 2 days and 5 days placebo (n=155) or levofloxacin for 7 days (n=155). The primary outcome measure was cure rate, and secondary outcome included need for additional antibiotics, ICU admission, reexacerbation rates and exacerbation free interval (EFI) within one year follow-up. Results: In ITT analysis, cure rate was 79.3% (n=123) and 74.2% (n=115) respectively in 2-day and 7-day groups. In PP analysis, cure rate was 78% (n=92) and 69% (n=82) respectively in 2-day and 7-day groups. The difference between both groups was not significant. The need for additional antibiotics and ICU admission rates were not significantly different between both groups. One-year reexacerbation rate was 34.8% (n=54) in 2-day group versus 29% (n=45) in 7-day group (p=0.19); the EFI was 121 days (interquartile range, 99-149) versus 110 days (interquartile range, 89-132) in 2-day and 7-day treatment groups respectively (p=0.73). No difference in adverse effects was detected.Conclusion: Levoﬂoxacin once daily for 2 days is not inferior to 7 days with respect to cure rate and hospital readmission in COPD exacerbations. Our finings would improve patient compliance and reduce the incidence of bacterial resistance and adverse effects.
Machine Learning Approaches for Early Prediction of Gestational Diabetes Mellitus Based on Prospective Cohort Study
Authors: Wang Jingyuan , Chen Xiujuan , Pan Yueshuai , Chen Kai , Zhang Yan , Li Qianqian , Sun Tong , Wang Haoyu , Wei Lili
Published: May 2021

Purpose: To develop and verify an early prediction model of gestational diabetes mellitus (GDM) using machine learning algorithm.Methods: The dataset collected from a pregnant cohort study in eastern China, from 2017 to 2019. It was randomly divided into 75% as the training dataset and 25% as the test dataset using the train_test_split function. Based on Python, four classic machine learning algorithm and a New-Stacking algorithm were first trained by the training dataset, and then verified by the test dataset. The four models were Logical Regression (LR), Random Forest (RT), Artificial Neural Network (ANN) and Support Vector Machine (SVM). The sensitivity, specificity, accuracy, and area under the Receiver Operating Characteristic Curve (AUC) were used to analyse the performance of models.Results: Valid information from a total of 2811 pregnant women were obtained. The accuracies of the models ranged from 80.09% to 86.91% (RF), sensitivities ranged from 63.30% to 81.65% (SVM), specificities ranged from 79.38% to 97.53% (RF), and AUCs ranged from 0.80 to 0.82 (New-Stacking).Conclusion: This paper successfully constructed a New-Stacking model theoretically, for its better performance in specificity, accuracy and AUC. But the SVM model got the highest sensitivity, the SVM model was recommends as the prediction model for clinical.
Proper Nacl Alleviates Osmotic Stress in Lycium Ruthenicum
Authors: Hu Jing , Hu Xiaoke , Zhang Huiwen , Yu Qiushi
Published: May 2021

Lycium ruthenicum is a salt-accumulating xerophytic species with excellent adaptability to adverse environments. Previous studies showed that a certain amount of NaCl resulted in promoting plant growth. To investigate the mechanism of Na+ to plant growth and the effect of drought stress, the growth, photosynthesis, water status and K+, Na+ transport related genes were subjected to different NaCl treatments and osmotic stress in the presence or absence of additional NaCl were assessed. Compared to the control, 50 mM NaCl strongly boosted the fresh weight, dry weight and relative growth rate of L. ruthenicum, and significantly increased the concentration of Na+, the K+ concentration in roots and stems remained stable, while which in leaves increased significantly. Furthermore, the addition of 50 mM NaCl sharply up-regulated the expression of LrSOS1 in roots, LrNHX and LrVP1 in leaves, LrHKT1 down-regulated in roots, it’s the reason why a high quantity of Na+ was accumulated in leaves under 50 mM NaCl. LrAKT1 up-regulated in roots, LrSKOR decreased first and then increased in roots, whereas LrSKOR in leaves remained stable and slightly up-regulated, thereby absorb a large amount of K+ by LrAKT1 and transport it to the leaf through LrSKOR. Moreover, external NaCl apparently alleviated the inhibition of osmotic stress in plant growth. Compared with the drought treatment, the addition of 50 mM NaCl significantly increased the Na+ and K+ content in roots, stems and leaves of L. ruthenicum, resulted in a decrease in proline content and no significant change in soluble sugar content, it is speculated that NaCl treatment could significantly improve the Na+, K+ concentration, thus enhance the osmotic regulation ability of plants, and then improve the photosynthesis and water status of L. ruthenicum.
Characteristics Recognition and Soft Multimedia System for Japanese Machine Translation and Edge-Driven Hardware Implementations
Authors: Song Gang
Published: May 2021

With the development of economic globalization, international exchanges and cooperation are increasingly frequent and in-depth. In this process, there is a serious obstacle, that is, language differences. Therefore, the development of high quality and practical machine translation system is of great significance. Japan has a close relationship with China, so it is necessary to acquire and process Japanese information. Japanese translation is the basis of Japanese information processing, which plays an important role in cross language information retrieval, machine translation, information extraction and other practical applications. In recent years, machine translation has made remarkable progress, but there is still much room for improvement in the quality of translation. Multimedia assisted instruction is an important application of computer technology in teaching field. In recent years, the wide application of multimedia courseware in all kinds of teaching has received good teaching results. With the development and deepening of Japanese teaching reform, contextualized teaching has been paid more and more attention. In this context, Japanese intensive teaching is also increasingly showing the trend of network, multimedia assisted. Therefore, this paper realizes the feature recognition and hardware structure of Japanese machine translation.
Frequency and Clinical Impact of WT1 Mutations in the Context of CEBPA-Mutated Acute Myeloid Leukemia
Authors: Wang Ting , Hua Haiying , Wang Zhen , Wang Biao , Cao Liujun , Qin Wei , Wu Pin , Chao Hongying , Lu XuZhang
Published: May 2021

Introduction: Several studies have confirmed that mutations in the Wilms tumor 1 (WT1) gene occur in adult acute myeloid leukemia (AML). However, few data are available regarding the incidence of WT1 mutations in CEBPAmut AML and their impact. Methods: We retrospectively analyzed the frequency and clinical impact of WT1 mutations in 220 newly diagnosed AML patients with CEBPA mutations. Chromosome karyotype analysis was performed by R or G banding method and further confirmed either by fluorescence in situ hybridization (FISH) and/or by multiple reverse transcription polymerase chain reaction (multiple RT-PCR). Mutations were detected with a panel of 112 mutational genes using next-generation sequencing (NGS). FLT3-ITD, NPM1 and CEBPA mutation were detected by PCR Sanger sequencing.Results: Overall, 30 WT1 mutations were detected in 29 of the 220 patients (13.18%) screened. These mutations clustered overwhelmingly in exon 7 (16 mutations in 15 patients), but they were also detected in exon 8 (n=6) and exon 9 (n=8). WT1-mutated (WT1mut) patients presented with lower platelet counts (P=0.0481), higher WT1 expression (P=0.0371), and a negative trend with the M5 subtype (P=0.07) compared to WT wild-type (WTwt) patients. WT1 mutations were found to be significantly more frequent in AML patients with double-mutated CEBPA (CEBPAdm) than in AML patients with single-mutated CEBPA (P=0.043). Of note, the concomitant mutations in epigenetic regulators were inversely correlated with WT1 mutations (P=0.003). Patients with newly diagnosed WT1mut AML had inferior relapse-free survival, event-free survival and overall survival compared with patients with WT1wt AML (P=0.002, 0.004, and 0.010, respectively). Conclusion: Our data showed that WT1 mutations are frequently identified in CEBPAmut AML, especially in CEBPAdm AML. Patients with WT1 mutations show distinct clinical features, a spectrum of comutations, and poor prognosis compared to WT1 wild-type patients.
Loss of Signal Transducer and Activator of Transcription 3 Impaired the Osteogenesis of Mesenchymal Progenitor Cells in Vivo and in Vitro
Authors: HUANG ZIJING , Feng Jingyi , Feng Xin , Chan Laiting , Lu Jiarui , Lei Lizhen , Huang Zhuwei , Zhang Xiaolei
Published: May 2021

Background: Signal transducer and activator of transcription 3 (Stat3) is a cytoplasmic transcription factor that participates in various biologic processes. Loss of Stat3 causes hyperimmunoglobulin E syndrome, presenting with skeletal disorders including osteoporosis, recurrent fractures, scoliosis, and craniosynostosis. The objective of this study is to explore the effect and mechanism of Stat3 on osteogenesis of mesenchymal progenitors.Methods: Stat3 was conditionally knockout (CKO) in mesenchymal progenitors by crossing the pair-related homeobox gene 1-cre (Prx1-Cre) with Stat3-floxed strain mice. Whole-mount-skeletal staining, histology, and Micro-CT were used to assess the differences between Stat3 CKO and control mice. Further, in vitro experiments were conducted to evaluate the osteogenesis potential of primary isolated bone marrow mesenchymal stem cells (BMSCs) from both control and Stat3 CKO mice. After osteogenic induction for 14d, alizarin red staining was used to show the calcium deposit, while the western blotting was applied to detect the expression of osteogenic markers.Results: Compared with the control, Stat3 CKO mice were present with shortened limbs, multiple fractures of long bone, and open calvarial fontanels. The abnormal growth plate structure and reduced collagen fiber were found in Stat3 CKO limbs. According to micro-CT analysis, the reduced cortical bone thickness and bone volume were found on Stat3 CKO mice. The in vitro osteogenic differentiation of BMSCs was inhibited in Stat3 CKO samples. After osteogenic induction for 14d, the significantly diminished calcium deposits were found in Stat3 CKO BMSCs. The decreased expression of osteogenic markers (OPN and COL1A1) was observed in Stat3 CKO BMSCs, compared with the control. Conclusions: Stat3 played a critical role in bone development and osteogenesis. Loss of Stat3 impaired the osteogenesis of mesenchymal progenitors in vivo and in vitro.