bluuebunny/crossref_metadata_2025 huggingface dataset:
A relational model for assessing internal communications and organizational bonds: the importance of affective relations and the role of the immediate supervisor
Authors: Videira Denise Pragana
Published: December 2023

Purpose – To analyze the factors related to the internal communication process that influence the organizational bonds (commitment, entrenchment, and consent) between workers and their employing organizations.
Design/methodology/approach – Qualitative and quantitative research instruments were employed in a sample field consisting of four large organizations in Brazil. Findings emerged from Content Analysis, Exploratory Factor Analysis (EFA) and Structural Equation Modelling (SEM).The qualitative phase involved the participation of 23 respondents. The quantitative phase sample comprised 401 respondents. A scale was developed to assess workers' perceptions of communication processes.
Findings – A relationship between communication processes and organizational bonds was confirmed. Immediate leader communication proved to be a highly significant factor in the internal communication process, as well as affective communication, which directly impacts commitment and acts on engaging communication, which in turn influences commitment. It was observed that the consent bond, through the subordination, directly impacts commitment, albeit in a negative manner.
Originality/value – The study contributes to the field of organizational communication by introducing the IOCS (Internal Organizational Communication Scale) and paves the way to further the still nascent debate on the forms of interaction between organizations and their employees resulting from new management models, labor contracts, as well as organizational value and purposes, stemming from the changes brought about by the Covid-19 heath crisis.
PEMODELAN DAN SIMULASI KELIMPAHAN ALGA DAN KONSENTRASI TSS PADA WADUK MENGGUNAKAN STRUCTURAL THINKING, EXPERIMENTAL LEARNING LABORATORY WITH ANIMATION (STELLA) DAN VENTANA SYSTEM (VENSIM)
Authors: Silmi Ai
Published: December 2023

Dari data aktual didapat konsentrasi TSS sebesar 147.18 mg/L dan jumlah alga 5.696.736,11 individu/liter. Kondisi waduk mengalami eutrofikasi dan tidak layak sebagai air baku air minum untuk kelas I dan II. Hasil simulasi dengan skenario 1 menunjukkan bahwa peruntukan waduk sesuai untuk bahan baku air minum karena alga berada dibawah 5 x 106 individu/liter. Hasil simulasi skenario 2 menunjukkan bahwa kondisi waduk tidak layak sebagai air baku air minum. Hasil simulasi skenario 3 menunjukkan bahwa peruntukan waduk sesuai untuk bahan baku air minum. Konsentrasi TSS dari input waduk tidak berpengaruh nyata terhadap konsentrasi TSS di waduk dan kelimpahan alga. Komponen KJA sangat sensitif perubahannya terhadap konsentrasi TSS dan kelimpahan alga di waduk.
Da (Suposta) Legitimação Kelseniana ao discurso de ódio nazista
Authors: Melo Vinicius
Published: December 2023

Este artigo tem como propósito analisar aspectos específicos do pensamento de Hans Kelsen, a fim de investigar se existem elementos que possam justificar uma suposta legitimação do discurso de ódio nazista com base em suas concepções. Será abordada a historicidade da institucionalização de ideias segregacionistas na legislação alemã, bem como o impacto dessas perspectivas nas minorias sociais do país. Além disso, serão examinados pontos-chave da obra “Teoria Pura do Direito”, assim como as questões relacionadas à perseguição político-ideológica sofrida por Hans Kelsen no contexto do século XX, com o intuito de alcançar o objetivo elencado. Adotar-se-á para tanto o método hipotético-dedutivo de Karl Popper e o tipo de pesquisa bibliográfica. Destacando-se a ampla relevância teórica e social do tema in fine, busca-se desmistificar as interpretações atribuídas ao autor austríaco e proporcionar uma análise mais racional de suas contribuições para a ciência jurídica.
Mecanismos de Fragilização Democrática:
Authors: Do Prado Haram Colucci Pedro Henrique
Published: December 2023

A presente pesquisa visa analisar o fenômeno do constitucionalismo abusivo, termo cunhado por David Landau para definir práticas que atingem as democracias contemporâneas por meio da utilização de mecanismos de alteração constitucional que enfraquecem a própria arquitetura institucional dos regimes. Analisa-se a decisão paradigmática do Supremo Tribunal Federal na ADPF nº 622, e a utilização do conceito pela Corte. Esta pesquisa de cunho exploratório, utiliza revisão documental e bibliográfica de obras que trabalham dinâmicas de comportamento nas democracias contemporâneas, dentro do escopo do método sociojurídico-crítico, confrontando os fenômenos sociais com as estruturas jurídico-políticas e normativas vigentes, a partir de uma análise interdisciplinar.
Bioequivalence study between two formulations of 10mg lenalidomide capsules in healthy male subjects under fasting conditions
Authors: Sverdloff Carlos , Rezende Vinicius Marcondes , de Cassia Val Ligia , Castro Nelly Cristina , Limón Maria Elena Cedano , Badii Mohammad H. , Kakarla Sreekanth , Pendela Murali , Bonnato Lygia
Published: December 2023

Objective: To evaluate pharmaceutical bioequivalence between two formulations of 10mg lenalidomide capsules in healthy male subjects under fasting conditions.

Material and Methods: An open label, monocentric, randomized, 2x2 crossover study in 32 healthy men under fasting conditions comparing two formulations of lenalidomide capsules. Analyte concentrations in human plasma were determined using a validated liquid chromatography with a tandem mass spectrometer detector method (UPLC-MS/MS).

Results: Statistical analysis has determined geometric mean of test/reference ratio, confidence intervals, and power of the test to the pharmacokinetic parameters Cmax and AUC0-t as required by Anvisa resolution, the geometric mean ratio (90%CI) of the test drug/reference drug were 84.01 to 108.10 for Cmax and 98.58 to 105.34 for AUC0-t. Power of the test was 89.9% for Cmax and 100.0% for AUC0-t.
Next-generation probiotics: Health-promoting bacteria of the human gut
Authors: Golić Nataša , Đokić Jelena , Tolinački Maja , Živković Milica
Published: December 2023

In recent years, a vast number of human diseases have been correlated with gut microbiota dysbiosis. The development of modern methods in molecular microbiology, such as the culturomics approach, as well as various multi-omics methods like next generation sequencing, transcriptomics and metabolomics analysis, coupled with large data sets correlation analysis, enabled the cultivation and characterization of novel anaerobic hitherto uncultivated Next-Generation Probiotics. In addition, the results of host-microbe interactions studies helped to reveal the mechanisms involved in the beneficial effects of Next-Generation Probiotics. Eventually, the obtained data on Next-Generation Probiotics will help to broaden the scientific knowledge on these bacteria, in terms of both their safety and health-promoting effects, unravel opportunities for the development of novel therapeutic strategies for prevention and treatment of tumors, metabolic, neuropsychiatric and other diseases, with the aim of relieving the symptoms of the diseases and increasing the quality of life for patients and their families. So far, the best characterized probiotics of the new generation are Akkermansia muciniphila, Faecalibacterium prauznitzii and Bacteroides fragilis.
The microbiome-gut-brain axis in multiple sclerosis
Authors: Radojević Dušan , Soković-Bajić Svetlana , Dinić Miroslav , Bisenić Aleksandar , Đokić Jelena , Golić Nataša
Published: December 2023

The microbiome-gut-brain axis (MGBA) represents a close two-way relationship between the gut and the central nervous system (CNS) mediated by the immune system, the enteric nervous system (ENS), the vagus nerve, and the gut microbiome. Gut microbes, including bacteria, fungi, and viruses, can communicate with the CNS and modulate the physiology of the brain in health and disease, which marks them as an important MGBA factor. It is becoming increasingly evident that gut microbiome dysbiosis is implicated in the onset and severity of different neurodegenerative and psychiatric diseases including multiple sclerosis (MS). MS is a chronic disease of the CNS associated with different genetic and environmental risk factors. Neuroinflammation and demyelination in the brain and the spinal cord are hallmark features of MS. The accumulating evidence shows that the MGBA, although a relatively new concept, has an important role in MS. Therefore, the purpose of this article is to review recent research on the gut-brain connection in MS, and to highlight MS-associated gut microbiota constituents and the role of bacterial metabolites in MS.
Sustainable organisation performance evaluation using balance scorecard and analytical hierarchical process
Authors: Swamy Arabinda , Mishra Sushant , Mishra R.K.
Published: December 2023

The present study uses the Analytic Hierarchy Process and Fuzzy Comprehensive method to evaluate the sustainable performance index with different sustainable dimensions on organisational performance measures. Limited integration methods available, inadequate exploration of sustainable dimensions, insufficient attention to key performance indicators, and lack of comparative studies have prompted the present study. This empirical study reveals that a balanced scorecard can be effectively applied to an aerospace organisation for sustainable performance evaluation. It is essential to select proper key performance indicators for a performance measuring system. This paper presents the study carried out on the sustainable performance evaluation in an aerospace organization in the Indian context and found the sustainability of the Organisation as moderate Level. The survey also identifies the Levels of different segments such as learning and growth, internal business, social and environmental dimensions, finance, customer dimension, etc. Suggestions are also included for the improvement of levels of various segments. The paper also covers the impact of locational differences or product segments on sustainable performance.
Possibilities of short supply chains in the sustainable logistics in Zala County
Authors: Szabó Károly , Szabó László
Published: December 2023

Climate change has been a known problem for a long time, but nowadays its effects becoming more powerful and palpable in our everyday life. Therefore, one of the most important topics of the social sciences nowadays, the identification of the sustainable solutions. As the problem of the climate change is very complex, we have to examine it from different aspects/territories/industries. Logistics is one of these territories. Today logistics is more and more criticized as the average supply chains contribute in a highlighted way to the environmental pollution. In the past academic discussion, Short Supply Chains appeared as a potential solution but so far only in the field of agricultural sciences yet. One of our research aims is the definition of the basic shortened supply chain framework within a supply chain can be called 'shortened' in Zala County. For this, we will examine the implemented short supply chains on the ground of the literature review. We will seek the answer for the second important aim, which is the potential application of this technique, with qualitative methods among Zala County enterprises.
Blow-up phenomena for a p(x)-biharmonic heat equation with variable exponent
Authors: Pişkin Erhan , Butakin Gülistan
Published: December 2023

In this paper, we deal with a p(x)-biharmonic heat equation with variable exponent under Dirichlet boundary and initial condition. We prove the blow up of solutions under suitable conditions.
Air pollution and its impact on human health: An overview of the situation in the Republic of Serbia
Authors: Vulović Jelena , Knežević Snežana , Jandrić-Kočić Marijana
Published: December 2023

Air pollution has become a major global concern with profound implications for public health worldwide. Among the most significant air pollutants are particulate matter, sulfur dioxide, nitrogen oxides, heavy metals, and ammonia, which have serious and wide-ranging effects on human health. Respiratory diseases, including asthma, chronic obstructive pulmonary disease (COPD), and pneumonia, are frequently associated with air pollution, while the risk of developing other serious conditions such as diabetes and cardiovascular problems is also elevated. Of particular concern is the exposure of children to air pollution, as their immune systems are not fully developed, and they spend more time outdoors, where pollution concentrations are often higher. In Serbia, as in many other countries, integrated intersectoral measures are necessary to reduce air pollution and protect the health of citizens. This paper aims to provide a basic overview of air pollution issues in Serbia and explore control and measurement measures to better understand the fundamental concepts and make progress in addressing this serious problem.
Nosocomnial pneumonia
Authors: Jovanović Bojan , Hadžibegović Adi , Avramović Jovana , Savić Milan , Rović Ivan , Šijan Đuro , Brezić Nebojša , Antonijević Jovana , Mirosavljević Sofija
Published: December 2023

Nosocomnial (hospital) pneumonias (hospital-acquired pneumonia - HAP) are defined as pneumonias in hospitalized patients that occur within 48 hours after admission to the hospital or later. These types of lung parenchymal infections are caused by pathogens that are present in the hospital environment. The incubation period is no longer than two days. Nosocomial pneumonias are the second most common of all hospital infections and the highest prevalence is recorded in intensive care units (ICU) (internal medicine and surgery). They represent a great burden on the health system everywhere in the world, because it is estimated that as many as 25% of infections in the ICU are hospital-acquired, and that 50% of all antibiotics are used precisely for their treatment. Recognizing the causative agent can be challenging, primarily due to the difficulty of adequate sputum sampling, but also due to the lack of understanding of the epidemiological situation in a particular health facility.
Analysis of flooding in the Lim basin in the territory of Montenegro with special reference to November and December 2010
Authors: Veličković Danijela
Published: December 2023

Catastrophic floods in the Lim basin on the territory of Montenegro were registered in November, December 2010 and January 2011. Since 1952, historical hydrological data related to the occurrence of large waters have been analyzed. In the area of the small basin of the river Lim, 2,785 people and two facilities for the water supply of citizens were affected by the floods. High waters during floods can cause damage of exceptional proportions. The floods of 2010 covered the tributaries of the Lim in the upper reaches: Ljuča, Vruja, Grnčar, Đurička rijeka, Plavska rijeka in the territory of the Plav municipality, Zlorečica, Kraštica, Trepačka rijeka in Andrijevica, Lim with tributaries through Bijelo Polje and Lim in the territory of Beran. High waters were registered in 2012 at the Grlja watercourse, the hydrological station at Grlja, and in 2016 at the hydrological stations Bijelo Polje na Lim, the hydrological station Plav and hs Dobrakovo. The floods had torrential and riverine character. After the catastrophic floods in 2010, flood protection systems were installed. Little attention is paid to the biological and biotechnical works on the arrangement of streams, so the possibility of the appearance of torrential streams increases, especially in the upper reaches of Lim, where torrential streams have been active for years, such as Martinić potok, Bjelicko, Bijelo potok, and through the municipality of Bijelo Polje the tributaries of Lim: Lješnička, Bistrička , Boljanska river, Lipnica, Orahovicki stream.
Mathematical results of the parameters affecting the uniform spreading productivity of combined plough fertilizers using the grapho-analytical method
Authors: Nuraddin Qurbanov
Published: December 2023

The correct application of mineral fertilizer norms and the study of effective energy saving methods, the use of fertilizers in soil and climate conditions for the cultivation of agricultural plants are the urgent tasks of modern agriculture.The main problem in the world is the uneven sowing and disturbance of the ecological situation during the application of fertilizers.So, in many developed countries, the mechanization of this field has been given a lot of attention. Many fertilizer spreading machines and equipment have been produced in this direction. However, in this field, accurate spreading of fertilizers and equal distribution in the soil remains a problem. Uneven fertilization significantly affects the characteristics of the crop and causes environmental pollution.The inhomogeneity of the field in terms of nutrients resulting from fertilization is often the main cause of uneven cropping. It causes yield loss in cereal crops, which can reach 25-60% in some years. Our research has determined that, depending on the design features of the spreaders and the quality of the fertilizers applied, the uneven distribution of the applied fertilizers can vary between 40-60% of the norm, which ultimately leads to nutrient deficiencies. It was observed that the productivity of cereal crops decreased by 11-15 centner/ha with the increase of uneven distribution of fertilizers in the field to 70-80%.In order to partially eliminate the scientific and technical deficiencies in grain growing, a combined plough was developed in our laboratory. Factors affecting productivity were analyzed by the grapho-analytical method of the combined plough, graphs were obtained by theoretical methods. Fertilizer rate, optimal selection of the speed of the aggregate creates conditions for obtaining the maximum productivity of mineral fertilizers in the field.Grapho-analytical methods are convenient for selecting the closest targets.
Jihadism in Sub-Saharan Africa: Specific features and threat assessment
Authors: Filijović Marko , Oddi Emanuele
Published: December 2023

This paper analyzes the activities of jihadists in the region commonly referred to as the "Black Continent". The authors provide an analysis of the development of jihadist ideology across the world, followed by a closer examination of its specific manifestations in sub-Saharan Africa. This research study utilized a model originally developed by Geoffrey Predmore in 2011 to analyze the insurgency in the North Caucasus. It includes three key aspects that theorists have identified as necessary for the success of the insurgency: the level of will of the actors involved in achieving the envisioned goals; choosing the strategy of the actors involved; and the extent of external support to the actors involved. The research was based on a content analysis methodology, utilizing a diverse range of reliable data sources, including official reports from international organizations, scientific publications, and newspaper articles. The authors concluded that holy warriors in sub-Saharan Africa possess a strong determination to achieve their goals at the local level. However, this willpower tends to decrease when it comes to global ambitions. When examining their strategy, it becomes evident that they have adopted a primarily indirect approach. Finally, in the context of external support to African jihadist groups, it has been observed that such support does exist. The basic assumption that sub-Saharan jihadists pose a distinct threat to internationally recognized countries in the region, and that they could potentially establish an entity similar to the Islamic State in sub-Saharan Africa, has been partially confirmed. Although they possess a strong will, an elaborate strategy, and specific external support for achieving local goals, it is unlikely that they will be able to constitute something like a caliphate in the near future.
Proposition of waste glass containers usage as secondary raw material for clay blocks production
Authors: Mirosavljević Zorica , Štrbac Dragana , Ubavin Dejan , Malešev Mirjana , Stanisavljević Nemanja , Štrbac Goran
Published: December 2023

The main objective of the present study was to propose the feasible usage of secondary raw material obtained from waste glass containers in the manufacture of clay blocks, driven by environmental benefits. Main goals were to reach a high content of waste glass in clay blocks, to use very low firing temperature and still obtain products with suitable physical and mechanical properties. Blocks with 10 wt. %, 20 wt. %, and 30 wt. % of waste glass in content were experimentally produced with the firing temperature of 880 °C. Relevant physical and mechanical properties were measured and their dependence on waste glass content was determined. Material flow analysis (MFA) showed that utilization of waste glass in clay block production can generate positive environmental impacts including landfill lifespan extension and contribution to the waste glass recycling.
Database management: Japan, postmodernity & architecture's digital turn
Authors: Tobey Aaron
Published: December 2023

This article offers a framing of the development and adoption of computer aided design tools by Japanese architects in the 1980s and early 1990s that counters the interpolation of their work into conventionalised narratives of a momentous "digital turn." It combines media theoretic and cultural studies approaches to analyse the design practices and design outputs of Japanese architects engaged with computers alongside prevailing political-economic policies and contemporary popular cultural genres/forms such as database novels. The article thereby elaborates on the formation of a "database imagination" of Japan and information management practices through which computer use was framed domestically and internationally in relation to emerging theories of aesthetic and technical postmodernity. Setting these domestic and international framings against one another, the article shows how efforts to construct a particular image of Japan were used by multiple groups to position the country and its architectural production within larger narratives of cultural and technological change. Finally, this positioning is examined as a site through which the cultural specificity of Japan and the co-constructive encounter of Japanese architects with computers was and continues to be negotiated.
A pragmatic view on Japanese architectural identity: Demystifying a monolithic construct
Authors: Capitanio Marco
Published: December 2023

Why is Japan's architectural legacy and practice, seen from within, very different from its perception abroad? A country's architectural identity is shaped by several aspects, including its tangible heritage, relationship with the other arts, construction technology, and everyday professional practice. The result is a layered product whose appearance can be remodelled to suit particular contexts and audiences. This paper shows how certain aspects of Japanese architectural identity, considered quintessential and monolithic overseas (atelier-style firms, minimalist aesthetic, technological drive), are instead only one half of dichotomies. Who is responsible for this process of curation? Is it a conscious or unconscious effort? Should the receiving end (i.e. both expert and lay audiences abroad) be more critical in their reception? First, the paper introduces the zenecon model, a fundamental and native component of the Japanese AEC industry, consistently underrepresented in the international construction and architecture discourse. Second, it clarifies how the minimalist zen aesthetic is counterbalanced by a more exuberant and haptic tradition tracing its roots back to the Neolithic Age. Third, it shows how technological advancement in certain specialised construction domains contrasts with the average performance and comfort level of (residential) buildings.
Urban morphology studies in the Russian scientific tradition
Authors: Kukina Irina , Logunova Elena
Published: December 2023

The formation of urban morphological science in Russia can be attributed to the 1950s, with the interest in the study of the urban history. The development of morphological research can be divided into four major periods. The first one is associated with the creation of methods for studying the development of urban form and architectural typology depending on land use and land ownership in the pre-socialist period (N. Gulyanitskyi, V. Lavrov, E. Kirichenko). The second can be characterized as predictive-conceptual. It was concluded that new modernist cities built in the 60-70s evolved according to the laws of the historical city and are little controlled by centralized urban planning (A. Gutnov). The third period is connected with the ideas relating to landscape unity and heterogeneity, the nexus of physical, biological and social processes. The mapping of morphological units was part of the historico-morphological and landscape approach to urban structural analysis (V. Gutsalenko, I. Kukina). At the present period one should state the introduction of the morphological high-technology methods under the pressure of the political and planning Codes adopted at the end of the twentieth century. They restore the forms of land ownership and uses, which change the urban form (A. Bolshakov, E. Logunova).
Reading and building Venice, 1984: Cappai, mainardis, pastor's case popolari as material culture
Authors: Maranelli Francesco
Published: December 2023

In the 1980s, Venice was a unique laboratory for studies on the relationship between contemporary architecture and the historical city, a matter which is critical today as well. Architecture projects of this period are precious testimonies to ways of reading the historical context and building within it. In February 1984, four architecture firms delivered the documentation required by the Venice Municipality's Extraordinary Housing Programme competition, concerning the construction of four housing projects in the Venetian territory. These were among the city's first new housing schemes directly operated by the Municipality after World War Two. Based on the analysis of archival documents, this study focuses on architects Cappai, Mainardis and Pastor's project, which proposed a reading of the city and their interpretation of housing as the expression of a 'material culture'. Beyond formal analogies, they chose to structure their project around the persistent material culture which underlay residential construction in both historical and contemporary Venice. Understanding the material culture of their time as inseparable from the building market, they adopted modern building industrialisation techniques. As the group was selected to build three schemes, their theoretical effort was eventually matched by an episode of actual prefabrication within the island's historical centre.
Simulation of accelerated ageing of polyester fabric
Authors: Dekanić Tihana , Šaravanja Ana , Volmajer Valh , Pušić Tanja
Published: December 2023

Human uncontrolled and careless habits and activities have disturbed the balance of the Earth's life cycle. Due to their effort to use natural resources as much as possible, humans have directly affected all the actors who live here, so that ecology has become an imperative today. Since the biggest polluters are factories in general, it can be stated that the textile industry is one of them. The increasing use of synthetic fibers in the production of textiles has led to some improvements in the form of mechanical, aesthetic and functional properties of the material. However, consumerism, the development of fast fashion, the rapid changes of fashion trends, irrational behavior and population growth have led to increased production of textiles based on synthetic fibers. Over the years, this has led to a slow accumulation of microfibers in the environment. Based on long-term test procedures under real conditions and with the aim of accelerating simulation, a standard polyester fabric is subjected to an artificial ageing process in this paper. By analyzing and characterizing the surface of the standard and the artificially aged fabric, and by instrumentally testing the tactile and mechanical properties, an attempt is made to gain insight into the behavior of the polyester fabric as a result of the applied modification. The results show that artificial ageing significantly affects the properties of polyester fabric, with a marked decrease in strength.
Mass transfer on rotating disk by adsorption and electrochemical methods
Authors: Šućurović Katarina , Jaćimovski Darko , Đuriš Mihal , Arsenijević Zorana , Bošković-Vragolović Nevenka
Published: December 2023

One of the ways to intensify the process is the use of rotating elements, which increase the mass transfer coefficients many times over. In this study, the mass transfer coefficient was determined by adsorption and electrochemical methods, using a rotating disk (RD) to study the effect of rotation on the mass transfer intensity. For adsorption method, a dilute solution of methylene blue was used, and silica gel foils on rotation disk were used as adsorbents. The measurements were performed under diffusion-controlled conditions, and the color intensity of the surface was determined using SIGMA Scan Pro. The study of mass transfer by electrochemical method was performed in batch systems with a volume of 20 dm3 and 0.8 dm3 , using a solution of sulfuric acid and copper sulfate, and potassium ferricyanide (III), potassium ferricyanide (II), and potassium chloride. Disks with diameters of 0.8 cm, 1 cm, 2 cm, 5.6 cm, and 20 cm were used in the rotation range up to 800 rpm. After determining the operating voltage, the current intensity was measured at different rpm and the mass transfer coefficients were calculated. It was found that the mass transfer coefficient increases as the rotation speed of the RD increases, and that is does not depend on the diameter of RD. It is shown that the current density increases with the increase of the RD speed, while the diffusion layer thickness decreases. A comparative analysis of the results obtained by the adsorption and electrochemical methods was made and the results were compared with literature correlations.
The impact of antioxidant diets, nutraceuticals and physical activity interventions in the prevention of cardiometabolic diseases: An overview
Authors: Parekh Neel , Merota Vipina , Joshi Ruchira , Kaur Ginpreet , Tuli Hardeep , Buttar Harpal
Published: December 2023

Hippocrates - Father of Medicine (ca 460-370 BC) - endorsed the cuative effects of foods; he said: "Leave your drugs in the chemist's pot if you can heal the patient with food". This review focuses on the management of cardio-metabolic diseases (CMDs) with nutraceuticals and antioxidant diets such as Allium sativum, turmeric, soybean, peptides, phytosterols, resveratrol, polyphenolic substances etc. CMDs are a cluster of conditions linked to altered fat and carbohydrate metabolism as well as macroand micro-vascular problems. CMDs cause severe pathophysiological and metabolic alterations in the body, resulting in the occurrence of chronic diseases like atherosclerosis, coronary heart disease and stroke, neurodegenerative ailments, fatty liver, kidney malfunction, hypercholesterolaemia, hyperlipidaemia, insulin resi-tance and some cancers, consequently imposing a very high economic burden on the healthcare costs. Currently used pharmacotherapies are not only expensive but also are associated with undesirable adverse events. Thus, there is an urgent need for affordable, cost-effective and alternative safe therapies for the prevention and management of CMDs. Holistic approaches targeted for health promotion and prevention of CMDs include the intake of antioxidant-rich diets, anti-inflammation wholesome foods and moderate physical activity (about 30 min/day). Such strategies will not only prevent obesity-related CMDs, type 2 diabetes mellitus (T2DM), coronary heart disease and stroke, but also will improve the quality of patient's life and consequently reduce healthcare burdens. Nutraceuticals and probiotics exhibit anti-inflammation, anti-aging, anti-obesity and anti-diabetic effects, thereby reducing the adverse health risks associated with CMDs. Antioxidants protect cell membranes and DNA from excessive free radicals, which contribute to CMD related diseases. Physical exercise along with dietary interventions helps to mitigate oxidative stress, improve blood triglyceride levels, increase HDL-cholesterol and reduce LDLcholesterol and reverse the biological markers associated with CMDs. Many studies have provided robust scientific evidence and demonstrated links between dietary interventions, nutraceuticals, probiotics, wholesome foods and physical activity for the prevention of CMDs. The major limitations in promoting nonpharmacological therapies for health and well-being benefits are a lack of public awareness and a paucity of clinical nutrition instruction for medical students on the merits of complementary methods for the prevention and management of CMDs. The goals of this review are to provide up-to-date knowledge about selected nutraceuticals, wholesome foods and physical activity in the prevention of CMDs and the underlying mechanisms associated with each intervention, which will ultimately improve patient's quality of life and assist in reducing healthcare costs globally.
Active Learning and Community Engagement: Pedagogical Synergy through the"Mobile Neuroscience Lab" Project
Authors: Gilbertson, Rebecca J. , Hessler Eric E. , Leff Dustyn J.
Published: December 2023

The Mobile Neuroscience Lab is a project that facilitates combined pedagogical strategies of active learning and neuroscience outreach as a service learning component of a physiological psychology course. The overall project goals were to improve science knowledge, foster oral communication, and encourage positive science attitudes and beliefs. Of these goals, positive science attitudes and beliefs were assessed. During active learning, university students completed hands-on activities corresponding to the physiological psychology course. Following, during the neuroscience outreach activity (“learning through teaching”), university students and middle school students engaged in small group activities (one university student to five middle school students) using the same hands-on activities. Assessment of the perceived benefit of the active learning showed that university and middle school students responded favorably to the hands-on activities. Students’ science attitudes were also assessed (Hillman et al., 2016) using a pre-test, post-test design. Data showed that the neuroscience activity did not change middle school science attitudes and beliefs (p > .05), possibly as the science attitudes and beliefs were already positive (moderate to high) prior to the outreach activity. However, qualitative data showed that the aspect of the neuroscience outreach activity that most assisted the middle school students in their learning was seeing the brain, touching the brain, and social interaction with the university students. Overall, the pedagogical strategies of active learning, and “learning through teaching”, were received with enthusiasm by university and secondary education students. Future studies will include classroom teachers’ assessment of these hands-on activities.
Electromagnetic Field Response to Impulsive Processes in the Earthquakes
Authors: V.Dovbnya B.
Published: December 2023

Looking for electromagnetic effects of earthquakes, pulse signals are detected preceding the moment of the event or following it. The advance or delay is from 0 s to 200 s. The signals are observed as single or pair pulses in the frequency range 0-5 Hz. Dynamical spectra of the signals are presented and their characteristics are discussed. The signals impact actively on the magnetosphere and ionosphere. As a result of such impact a sharp change in the regime of geomagnetic pulsation excitation may occur. The detected response of the pulsations is considered and analyzed.
Seismotectonic Stress Regime and Airborne-Gravity Lineament Investigation of the Caribbean region and its Kinematic implications
Authors: AdekunleEluyemi Ayodeji
Published: December 2023

The tectonic stress regime of the Caribbean region has been studied by stress tensor inversion analysis for the area bounded by Latitudes 17.32o to 23.79o N and Longitudes 81.47o to -60.56o E. A total of two hundred and twenty (220) fault plane solutions (FPS), made up of the seismic (earthquake) events that have occurred in the region of the study were found on the data catalog of the project website of the global centroid moment tensor, were employed in this study. To characterize the stress regimes of the region of study, the classification of the region based on the global moment tensor project is as follows: Cuba-zone, Haiti-zone, Dominican-republic, Monapassage, Puerto Rico, Virgin-Island and the Leeward Island. The gravity geophysical method revealed the presence of multiple or swarms of fractured lines within the same geographical range of study which might have developed over the years as a result of the interaction and coupling effect of the plate boundaries that have close proximity to the region of study. The seismicity pattern indicates that none of the provinces or countries located within the Caribbean region is devoid of large-magnitude earthquake occurrences capable of wreaking severe havoc on the immediate environment. Obviously, our stress tensor inversion result indicates two types of stress regimes namely compression and the strike-slip with different orientations. Cuba-zone, Haiti-zone, Dominican Republic, Monapassage, and Leeward Island are governed mainly by compression stress regimes. In contrast, the strike-slip stress regimes mainly govern the Puerto Rico and the Virgin Island.
Factores que influyen en las medidas de prevención de la tuberculosis pulmonar y propuesta de un plan de capacitación en la población de San Clemente – Pisco
Authors:   , Antezana Quispe Jose Luis , Valencia Rojas Edgar Andres
Published: December 2023

Objetivo: Identificar los factores que influyen en las medidas de prevención de la tuberculosis pulmonar en pacientes atendidos en centro de salud en el periodo 2015 – 2016, San Clemente – Pisco. Materiales y métodos: Investigación de tipo observacional, analítica, transversal, retrospectiva. Sobre una población de 61 pacientes con tuberculosis pulmonar que son comparados con 61 pacientes sin tuberculosis pulmonar en un estudio de casos y controles. Resultados: Los resultados obtenidos fueron que el grado de conocimiento sobre la tuberculosis pulmonar es un factor que influye en las actividades preventivas de la tuberculosis pulmonar de la población de San Clemente – Pisco Enero – Junio 2017. Cuando las actividades preventivas promocionales no son realizadas de una forma adecuada pueden ser considerados uno de los factores que influye en la aparición de nuevos casos de tuberculosis pulmonar en la población de San Clemente. El grado de instrucción primaria y secundaria son considerados como un factor que influye en la prevención de la tuberculosis pulmonar de la población de San Clemente. La condición económica media y baja también son considerados como un factor que influye en la prevención de la tuberculosis pulmonar de la población de San Clemente. Conclusión: El estudio demostró que el desconocimiento sobre la tuberculosis, el no tener actividades preventivas promocionales de salud, el tener un grado de instrucción primaria o secundaria y ser de condición económica bajo o medio son un factor que influye en la prevención de la tuberculosis pulmonar de la población de San Clemente.
Efectividad del programa de suplementación con micronutrientes para la prevención de la anemia infantil en el Centro de Salud Paramonga
Authors:   , Vidal Alvarado Monica Giovanna
Published: December 2023

Con el objetivo de evaluar la efectividad del programa de suplementación con micronutrientes en polvo (MNP) para la prevención y reducción de la anemia infantil, se realizó la investigación de enfoque cuantitativa, por cuanto se abordaron variables características del objeto de estudio, datos estadísticos y numéricos relacionados con la suplementación con micronutrientes en niñas y niñas de 6 a 12 meses que acudieron al Centro de Salud Paramonga. Los resultados obtenidos refieren que durante el periodo abril 2015 a marzo 2016, iniciaron 170 niños suplementación con micronutrientes, y solo 120 (70.6%) niños concluyeron la suplementación con MNP. Con respecto al número de meses que terminaron la suplementación con MNP con 360 sobres los niños que iniciaron tratamiento, se observó que el 13.5% cumplió con el ciclo de administración de 12 meses, el 21.8% lo termino entre 14 a 18 meses mientras que el 15.9 % lo culmino entre 19 y 24 meses. Así mismo solo al 49.4 % se les realizó dosaje de hemoglobina al consumir 180 sobres de MNP, mientras que de los 120 niños que consumieron 360 sobres de MNP al 38.3 % se le realizo dosaje de hemoglobina al culminar el esquema de suplementación. Con respecto a la consejería nutricional el 84.7% recibió consejería nutricional sin embargo entre el 30.53% al 43.16 % de las consejerías nutricionales tienen solo una duración de 7 minutos a 10 minutos en promedio. Según los resultados obtenidos podemos concluir que a distribución de los micronutrientes no se realizó de manera oportuna y adecuada como lo establece la normatividad del sector salud lo que ha ocasionado una baja adherencia a la suplementación.
Niveles de estrés, ansiedad y depresión en cirujanos dentistas durante la pandemia COVID-19. Lima, 2021
Authors:   , Turpo Claudio Denisse Linda
Published: December 2023

Objetivo: Determinar los niveles de estrés, ansiedad y depresión que tienen los Cirujanos Dentistas durante la pandemia COVID-19 en Lima en el año 2021. Materiales y métodos: En el presente estudio observacional, descriptivo de tipo transversal, se obtuvo una muestra conformada por 181 Cirujanos Dentistas de la ciudad de Lima, donde la técnica de muestreo utilizada fue snowball o bola de nieve, técnica de muestreo no probabilística. Se realizó la encuesta utilizando un cuestionario en Google Forms el cual se difundió mediante plataformas en línea por el contexto de la pandemia, donde se utilizó la escala de Depresión, Ansiedad y Estrés-21 (DASS-21) incluyendo ítems sociodemográficos. Las respuestas fueron recogidas y exportadas en el programa Microsoft Excel, posteriormente se analizaron en el programa SPSS v.26. Resultados: Con respecto a la salud mental de los odontologos de la ciudad de Lima en relacion al estrés, ansiedad y depresión se obtuvo que el nivel normal fue el mas frecuente. Sin embargo en cuanto al nivel de estrés se obtuvo que un 19,9% de cirujanos dentistas presentaron estrés leve. Acerca del factor ansiedad un 10,5% manifestaron una ansiedad leve y moderada, mientras que en el factor depresión el 14,4% de la muestra presento depresión moderada, de los cuales destaca el sexo femenino con una depresión moderada del 9,9%. Conclusiones: Existe una escasez de investigaciones que aborden problemas de salud mental en los odontólogos a nivel mundial, por lo que esta investigación sirve como precedente en la literatura en el Perú, donde hasta la fecha sería el primer estudio en el país en evaluar los efectos psicológicos de la pandemia en odontólogos. El presente estudio en cirujanos dentistas muestra que existe una asociación significativa entre el nivel de estrés y el COVID-19 como amenaza financiera personal (p<0.05), así mismo existe una asociación entre el nivel de depresión y diagnóstico de COVID-19 (p<0.05).
Presencia de Cryptococcus neoformans en heces de palomas en el Regimiento de Caballería “Mariscal Domingo Nieto”, Cercado de Lima, 2021
Authors:   , Montoya Carrizales Alejandro Octavio
Published: December 2023

Objetivo: Determinar la presencia de Cryptococcus neoformans en heces de las palomas en el Regimiento de Caballería “Mariscal Domingo Nieto” del cercado de Lima, 2021. Materiales y Método: El tipo de investigación fue descriptivo, de corte transversal y observacional. La población estuvo conformada (1000 aves) en la zona de El Agustino. La muestra se determinó con un total de 200 muestras de excretas frescas y secas de palomas en cinco escuadrones que estuvo conformado en grupos de 40 heces en cada escuadrón (A, B, C, D y C/S) de las instalaciones del Regimiento de Caballería (RC). La técnica de recolección de datos fue una Ficha que permitió observar la presencia de heces de las palomas en protección del personal militar y equinos. Resultados: Se obtuvo del total de 200 muestras de heces, el 46,5% (93) demostraron presencia del Cryptococcus neoformans en excretas secas, mientras que hay ausencia de C. neoformans en el 27,5% (55) de heces secas y 26,0% (52) de heces frescas. Conclusión: Existe presencia de Cryptococcus neoformans en heces de las palomas en el Regimiento de Caballería “Mariscal Domingo Nieto” del Cercado de Lima, lo cual es un riesgo para la salud pública y el medio ambiente.
Factores de riesgo asociados al precáncer de cérvix en pacientes del Hospital Félix Torrealva Gutiérrez. Ica. 2019
Authors:   , Lovera Tataje Iris Avelina , Ybaseta Soto Marjorie Fabiola Victoria
Published: December 2023

Objetivo: Determinar los factores asociados a la presencia del precáncer de cérvix en las pacientes atendidas en el Hospital Félix Torrealva Gutiérrez. Ica. 2019. Tipo y Diseño: El enfoque es de tipo cuantitativo, el tipo de estudio es analítico de diseño caso – control. La población estuvo conformada por un total 11452 pacientes mujeres que se le realizaron un tamizaje de Papanicolau. Se seleccionó una muestra de 390 mujeres: 130 casos (diagnosticadas con precáncer de cérvix confirmados histológicamente) y 260 controles (sin la presencia de precáncer de cérvix). La información se recolectó de las historias clínicas mediante la aplicación de una ficha de recolección de datos. Resultados: Se determinaron los factores de riesgo asociados a la presencia de precáncer de cérvix, posterior a realizar el análisis multivariado: Tener de 15 a 24 años (OR: 17.0; IC95%: 3.6 - 80.3), tener de 2 o más parejas sexuales en su vida (OR: 97.3; IC95%: 37.7- 251.3), no utilizar método del ritmo (OR: 9.0; IC95%: 2.7 - 30.4) y tener una ITS (OR: 15.7; IC95%: 1.7 - 331.3). Conclusión: Se determinó la existencia de factores de riesgo que están asociados significativamente a la presencia de precáncer en las mujeres estudiadas.