bluuebunny/crossref_metadata_2025 huggingface dataset:
Chemical-genetic profile analysis of five inhibitory compounds in yeast
Authors: Alamgir Md , Erukova Veronika , Jessulat Matthew , Azizi Ali , Golshani Ashkan
Published: August 2010

Background

Chemical-genetic profiling of inhibitory compounds can lead to identification of their modes of action. These profiles can help elucidate the complex interactions between small bioactive compounds and the cell machinery, and explain putative gene function(s).

Results

Colony size reduction was used to investigate the chemical-genetic profile of cycloheximide, 3-amino-1,2,4-triazole, paromomycin, streptomycin and neomycin in the yeast Saccharomyces cerevisiae. These compounds target the process of protein biosynthesis. More than 70,000 strains were analyzed from the array of gene deletion mutant yeast strains. As expected, the overall profiles of the tested compounds were similar, with deletions for genes involved in protein biosynthesis being the major category followed by metabolism. This implies that novel genes involved in protein biosynthesis could be identified from these profiles. Further investigations were carried out to assess the activity of three profiled genes in the process of protein biosynthesis using relative fitness of double mutants and other genetic assays.

Conclusion

Chemical-genetic profiles provide insight into the molecular mechanism(s) of the examined compounds by elucidating their potential primary and secondary cellular target sites. Our follow-up investigations into the activity of three profiled genes in the process of protein biosynthesis provided further evidence concerning the usefulness of chemical-genetic analyses for annotating gene functions. We termed these genes TAE2, TAE3 and TAE4 for translation associated elements 2-4.
Intraoperative blood loss during different stages of scoliosis surgery: A prospective study
Authors: Modi Hitesh N , Suh Seung-Woo , Hong Jae-Young , Song Sang-Heon , Yang Jae-Hyuk
Published: August 2010

Background

There are a number of reasons for intraoperative blood loss during scoliosis surgery based on the type of approach, type of disease, osteopenia, and patient blood profile. However, no studies have investigated bleeding patterns according to the stage of the operation. The objective of this prospective study was to identify intraoperative bleeding patterns in different stages of scoliosis surgery.

Methods

We prospectively analyzed the estimated blood loss (EBL) and operation time over four stages of scoliosis surgery in 44 patients. The patients were divided into three groups: adolescent idiopathic (group 1), spastic neuromuscular (group 2) and paralytic neuromuscular (group 3). The per-level EBL and operation times of the groups were compared on a stage-by-stage basis. The bone marrow density (BMD) of each patient was also obtained, and the relationship between per-level EBL and BMD was compared using regression analysis.

Results

Per-level operation time was similar across all groups during surgical stage (p > 0.05). Per-level EBL was also similar during the dissection and bone-grafting states (p > 0.05). However, during the screw insertion stage, the per-level EBL was significantly higher in groups 2 and 3 compared to group 1 (p < 0.05). In the correction stage, per-level EBL was highest in group 3 (followed in order by groups 2 and 1) (p < 0.05). Preoperative BMD indicated that group 3 had the lowest bone quality, followed by groups 2 and 1 (in order), but the preoperative blood indices were similar in all groups. The differences in bleeding patterns in the screw insertion and correction stages were attributed to the poor bone quality of groups 2 and 3. Group 3 had the lowest bone quality, which caused loosening of the bone-screw interface during the correction stage and led to more bleeding. Patients with a T-score less than -2.5 showed a risk for high per-level EBL that was nine times higher than those with scores greater than -2.5 (p = 0.003).

Conclusions

We investigated the blood loss patterns during different stages of scoliosis surgery. Patients with poor BMD showed a risk of blood loss nine times higher than those with good BMD.
Expression of the apoptosis-related genes BCL-2 and BAD in human breast carcinoma and their associated relationship with chemosensitivity
Authors: Yu Bing , Sun Xin , Shen Hong-yan , Gao Feng , Fan Yuan-ming , Sun Zhi-jun
Published: August 2010

Objective

To evaluate the expression of BCL-2 and BAD genes in tissues of breast carcinoma and investigate the relationship between the expression of BCL-2 and BAD in breast cancer cells with chemosensitivity.

Methods

Immunohistochemical technique was used to detect the expression of BCL-2, BAD in 10 normal breast tissues, 10 breast fibroadenoma tissues, 40 youth human breast carcinoma tissues, 40 menopause human breast carcinoma tissues. And to detect the expression of ER, PR in 80 human breast carcinoma tissues. 20 Surgical samples of breast cancer, diagnosed by pathology, were obtained from The First Affiliated Hospital of Chongqing Medical University. The cancer sample cells were cultured separately in the incubator at 37°C, 5% CO2 in vitro. The rate of inhibition of cancer cells in 4 kinds of anticancer drugs-- Epirubicin Adriamycin (EADM),5-Fluorouracil (5-Fu), Navelbine(NVB) and Diaminedichloroplatinum (DDP), were assayed by MTT method.

Results

The expression of BCL-2, BAD genes in young human breast carcinoma tissues were lower than that in menopause human breast carcinoma tissues (
P

< 0.05). There was a negative correlation between the positive expression rate of BCL-2 and histologic grade or the lymph node metastasis (
P

< 0.05). There was a positive correlation between the expression rates of BCL-2 and of ER, PR (
P

< 0.05). The expression of BAD had no relationship with the expression of ER, PR, histologic grade and the lymph node metastasis(
P

=

NS
). Sensitivity rates of 20 breast cancer cells in 0.1 × PPC within 48 h in vitro were 30% EADM,20% 5-Fu,45% NVB and 25% DDP. Respectively, the rate of inhibition of EADM,5- Fu, NVB and DDP were significantly higher in the BCL-2 negative cancer cells than in the BCL-2 positive cancer cells. A negative correlation was found between expression of BCL-2 and chemosensitivity for all the 4 anticancer drugs. The inhibition rates of EADM and NVB were significantly lower in the BAD negative cancer cells than in the BAD positive cancer cells. A positive correlation was found between expression of BAD and chemosensitivity for Epirubicin.

Conclusion

The expression of BCL-2 and BAD can be used as prognosis factors of breast cancer. Detection of the BCL-2 protein expression level, particularly, combined with the detection of the expression of BCL-2 and BAD as well as ER and PR were helpful in confirming the prognosis of breast carcinoma. The combined detection of BCL-2 and BAD may be markers for predicting the responses to anticancer drugs.
Serum Bilirubin and Genes Controlling Bilirubin Concentrations as Biomarkers for Cardiovascular Disease
Authors: Lin Jing-Ping , Vitek Libor , Schwertner Harvey A
Published: August 2010

BACKGROUND

Serum bilirubin has been consistently shown to be inversely related to cardiovascular disease (CVD). Recent studies showed serum bilirubin to be associated with CVD-related factors such as diabetes, metabolic syndrome, and body mass index. Although the association of serum bilirubin with CVD has been found in both retrospective and prospective studies, less information is available on the role of genes that control bilirubin concentrations and their association with CVD.

CONTENT

In this review, we provide detailed information on the identity of the major genes that control bilirubin concentrations and their association with serum bilirubin concentrations and CVD risk. We also update the results of the major studies that have been performed on the association between serum bilirubin, CVD, and CVD-related diseases such as diabetes or metabolic syndrome. Studies consistently indicate that bilirubin concentrations are inversely associated with different types of CVD and CVD-related diseases. A conditional linkage study indicates that UGT1A1 is the major gene controlling serum bilirubin concentrations, and this finding has been confirmed in recent genomewide association studies. Studies also indicate that individuals homozygous for UGT1A1*28 have a significantly lower risk of developing CVD than carriers of the wild-type alleles.

Serum bilirubin has a protective effect on CVD and CVD-related diseases, and UGT1A1 is the major gene controlling serum bilirubin concentrations. Pharmacologic, nonpharmacologic, or genetic interventions that increase serum bilirubin concentrations could provide more direct evidence on the role of bilirubin in CVD prevention.
Liver Fat Content in Type 2 Diabetes: Relationship With Hepatic Perfusion and Substrate Metabolism
Authors: Rijzewijk Luuk J. , van der Meer Rutger W. , Lubberink Mark , Lamb Hildo J. , Romijn Johannes A. , de Roos Albert , Twisk Jos W. , Heine Robert J. , Lammertsma Adriaan A. , Smit Johannes W.A. , Diamant Michaela
Published: August 2010

OBJECTIVE

Hepatic steatosis is common in type 2 diabetes. It is causally linked to the features of the metabolic syndrome, liver cirrhosis, and cardiovascular disease. Experimental data have indicated that increased liver fat may impair hepatic perfusion and metabolism. The aim of the current study was to assess hepatic parenchymal perfusion, together with glucose and fatty acid metabolism, in relation to hepatic triglyceride content.

RESEARCH DESIGN AND METHODS

Fifty-nine men with well controlled type 2 diabetes and 18 age-matched healthy normoglycemic men were studied using positron emission tomography to assess hepatic tissue perfusion, insulin-stimulated glucose, and fasting fatty acid metabolism, respectively, in relation to hepatic triglyceride content, quantified by proton magnetic resonance spectroscopy. Patients were divided into two groups with hepatic triglyceride content below (type 2 diabetes-low) or above (type 2 diabetes-high) the median of 8.6%.

RESULTS

Type 2 diabetes-high patients had the highest BMI and A1C and lowest whole-body insulin sensitivity (ANOVA, all P < 0.001). Compared with control subjects and type 2 diabetes-low patients, type 2 diabetes-high patients had the lowest hepatic parenchymal perfusion (P = 0.004) and insulin-stimulated hepatic glucose uptake (P = 0.013). The observed decrease in hepatic fatty acid influx rate constant, however, only reached borderline significance (P = 0.088). In type 2 diabetic patients, hepatic parenchymal perfusion (r = −0.360, P = 0.007) and hepatic fatty acid influx rate constant (r = −0.407, P = 0.007) correlated inversely with hepatic triglyceride content. In a pooled analysis, hepatic fat correlated with hepatic glucose uptake (r = −0.329, P = 0.004).

CONCLUSIONS

In conclusion, type 2 diabetic patients with increased hepatic triglyceride content showed decreased hepatic parenchymal perfusion and hepatic insulin mediated glucose uptake, suggesting a potential modulating effect of hepatic fat on hepatic physiology.
Effect of Intrauterine Diabetes Exposure on the Incidence of End-Stage Renal Disease in Young Adults With Type 2 Diabetes
Authors: Pavkov Meda E. , Hanson Robert L. , Knowler William C. , Sievers Maurice L. , Bennett Peter H. , Nelson Robert G.
Published: August 2010

OBJECTIVE

We examined the effect of intrauterine diabetes exposure (IDE) on the incidence of diabetic end-stage renal disease (ESRD) in Pima Indians with type 2 diabetes.

RESEARCH DESIGN AND METHODS

Individuals were followed from their first diabetic examination until December 2006, death, ESRD, or age of 45 years.

RESULTS

Among the 1,850 diabetic participants, 102 had IDE. ESRD developed in 57, 5 of whom had IDE. Cumulative incidence of ESRD by age 45 was 19.3% in participants with IDE and 5.1% in those without; the age- and sex-adjusted incidence rate ratio was 4.12 (95% CI 1.54–11.02). After additional adjustment for age at diabetes onset, ESRD incidence was similar in the two groups (incidence rate ratio 1.38, 95% CI 0.45–4.24).

CONCLUSIONS

IDE increases the age- and sex-adjusted incidence of ESRD fourfold in young adults with type 2 diabetes, mediated primarily by the earlier onset of type 2 diabetes in those with IDE.
Sugar-Sweetened Beverages and Risk of Metabolic Syndrome and Type 2 Diabetes
Authors: Malik Vasanti S. , Popkin Barry M. , Bray George A. , Després Jean-Pierre , Willett Walter C. , Hu Frank B.
Published: August 2010

OBJECTIVE

Consumption of sugar-sweetened beverages (SSBs), which include soft drinks, fruit drinks, iced tea, and energy and vitamin water drinks has risen across the globe. Regular consumption of SSBs has been associated with weight gain and risk of overweight and obesity, but the role of SSBs in the development of related chronic metabolic diseases, such as metabolic syndrome and type 2 diabetes, has not been quantitatively reviewed.

RESEARCH DESIGN AND METHODS

We searched the MEDLINE database up to May 2010 for prospective cohort studies of SSB intake and risk of metabolic syndrome and type 2 diabetes. We identified 11 studies (three for metabolic syndrome and eight for type 2 diabetes) for inclusion in a random-effects meta-analysis comparing SSB intake in the highest to lowest quantiles in relation to risk of metabolic syndrome and type 2 diabetes.

RESULTS

Based on data from these studies, including 310,819 participants and 15,043 cases of type 2 diabetes, individuals in the highest quantile of SSB intake (most often 1–2 servings/day) had a 26% greater risk of developing type 2 diabetes than those in the lowest quantile (none or <1 serving/month) (relative risk [RR] 1.26 [95% CI 1.12–1.41]). Among studies evaluating metabolic syndrome, including 19,431 participants and 5,803 cases, the pooled RR was 1.20 [1.02–1.42].

CONCLUSIONS

In addition to weight gain, higher consumption of SSBs is associated with development of metabolic syndrome and type 2 diabetes. These data provide empirical evidence that intake of SSBs should be limited to reduce obesity-related risk of chronic metabolic diseases.
Microsatellites for the mangrove tree Avicennia germinans (Acanthaceae): Tools for hybridization and mating system studies
Authors: Mori Gustavo M. , Zucchi Maria I. , Sampaio Iracilda , Souza Anete P.
Published: August 2010

• Premise of the study: We developed a new set of microsatellite markers for the black mangrove Avicennia germinans, to provide new informative tools for further studies of the mating system, interspecific hybridization, and population genetics.

• Methods and Results: We used the microsatellite‐enriched library approach to isolate and characterize 25 new primer pairs. Sixteen of them are polymorphic, showing a variable degree of variation in A. germinans, while nine were monomorphic in the samples examined. Eight exhibited private alleles in A. schaueriana.

• Conclusions: These results indicate that these new microsatellite markers will be useful molecular tools for further studies of A. germinans and A. schaueriana population genetics, mating systems, and hybridization.
The Absence of IDO Upregulates Type I IFN Production, Resulting in Suppression of Viral Replication in the Retrovirus-Infected Mouse
Authors: Hoshi Masato , Saito Kuniaki , Hara Akira , Taguchi Ayako , Ohtaki Hirofumi , Tanaka Ryo , Fujigaki Hidetsugu , Osawa Yosuke , Takemura Masao , Matsunami Hidetoshi , Ito Hiroyasu , Seishima Mitsuru
Published: August 2010

Indoleamine 2,3-dioxygenase, the l-tryptophan–degrading enzyme, plays a key role in the powerful immunomodulatory effects on several different types of cells. Because modulation of IDO activities after viral infection may have great impact on disease progression, we investigated the role of IDO following infection with LP-BM5 murine leukemia virus. We found suppressed BM5 provirus copies and increased type I IFNs in the spleen from IDO knockout (IDO−/−) and 1-methyl-d-l-tryptophan–treated mice compared with those from wild-type (WT) mice. Additionally, the number of plasmacytoid dendritic cells in IDO−/− mice was higher in the former than in the WT mice. In addition, neutralization of type I IFNs in IDO−/− mice resulted in an increase in LP-BM5 viral replication. Moreover, the survival rate of IDO−/− mice or 1-methyl-d-l-tryptophan–treated mice infected with LP-BM5 alone or with both Toxoplasma gondii and LP-BM5 was clearly greater than the survival rate of WT mice. To our knowledge, the present study is the first report to observe suppressed virus replication with upregulated type I IFN in IDO−/− mice, suggesting that modulation of the IDO pathway may be an effective strategy for treatment of virus infection.
Cutting Edge: Association with IκB Kinase β Regulates the Subcellular Localization of Homer3
Authors: Yatherajam Gayatri , Banerjee Pinaki P. , McCorkell Kelly A. , Solt Laura A. , Hanson Eric P. , Madge Lisa A. , Kang Shin , Worley Paul F. , Orange Jordan S. , May Michael J.
Published: August 2010

The signaling and adaptor protein Homer3 plays a role in controlling immune homeostasis and self-reactivity. Homer3 is recruited to the immune synapse (IS) following TCR ligation, although the mechanisms regulating this subcellular localization are unknown. We show that Homer3 specifically associates with a novel ubiquitin-like domain in the IκB kinase (IKK) β subunit of the IKK complex. Homer3 associates with IKKβ in T cells and colocalizes with the IKK complex at the IS. However, Homer3 is not required for IKK activation, as NF-κB signaling is intact in Homer3-deficient T cells. Instead, the IKK complex recruits Homer3 to the IS following TCR engagement, and we present evidence that this association regulates actin dynamics in T cells. These findings identify a novel interaction between two major signaling proteins and reveal an unexpected NF-κB–independent function for the IKK complex in regulating the subcellular localization of Homer3.
Netrin-1 Regulates Th1/Th2/Th17 Cytokine Production and Inflammation through UNC5B Receptor and Protects Kidney against Ischemia–Reperfusion Injury
Authors: Tadagavadi Raghu Kempegowda , Wang Weiwei , Ramesh Ganesan
Published: August 2010

Overwhelming evidence suggests that ischemia–reperfusion injury of the kidney is an inflammatory disease mediated by innate and adoptive immune systems. The neuronal guidance molecule netrin-1 was shown to modulate inflammatory responses. Given that ischemic kidney is particularly prone to reperfusion-elicited inflammation, we sought to determine the function of netrin-1 and its receptor UNC5B in ischemia–reperfusion-induced inflammation. Renal ischemia–reperfusion caused a rapid decrease in serum netrin-1 levels. Administration of recombinant netrin-1 before or after renal ischemia–reperfusion reduced kidney injury, apoptosis, monocyte and neutrophil infiltration, and cytokine (IL-6, IL-1β, and TNF-α) and chemokine (MCP-1, macrophage-derived cytokine, monokine-induced IFN-γ, keratinocyte-derived chemokine, and chemokine with 6 cysteines) production. Analysis for different netrin-1 receptors on leukocytes showed very high expression of UNC5B but not UNC5C, UNC5D, neogenin, or deleted in colorectal cancer. Expression of UNC5A was low. Neutralization of UNC5B receptor reduced netrin-1–mediated protection against renal ischemia–reperfusion injury, and it increased monocyte and neutrophil infiltration, as well as serum and renal cytokine and chemokine production, with increased kidney injury and renal tubular cell apoptosis. Finally, investigation into netrin-1’s effect on CD4 T cell stimulation showed suppression of Th1/Th2/Th17 cytokine (IL-2, IL-6, IL-10, IL-13, IL-17, IFN-γ, IL-4, and TNF-α) production in vitro. Our studies demonstrate that netrin-1 acting through UNC5B receptor reduces renal ischemia–reperfusion injury and its associated renal inflammation.
IL-33 Exacerbates Eosinophil-Mediated Airway Inflammation
Authors: Stolarski Bartosz , Kurowska-Stolarska Mariola , Kewin Peter , Xu Damo , Liew Foo Y.
Published: August 2010

IL-33 has emerged as an important mediator in the immunopathogenesis of allergy and asthma. However, the role of IL-33 in eosinophil-mediated inflammation has not been fully explored. In this article, we report that IL-33 directly stimulates eosinophil differentiation from CD117+ progenitors in an IL-5–dependent manner. Although resting eosinophils expressed moderate levels of the IL-33R α-chain (ST2L), eosinophils that accumulated in the airways of mice with OVA-induced asthma expressed increased amounts of ST2L. In vitro, IL-33 and GM-CSF are potent inducers of ST2L expression on eosinophils, and IL-33 induced the production of IL-13, CCL17, and TGF-β by eosinophils. In adoptive-transfer experiments, IL-33 exacerbated eosinophil-mediated airway inflammation by increasing the levels of eosinophils, macrophages, lymphocytes, IL-13, TGF-β, CCL3, CCL17, and CCL24 in the lungs. IL-33 also enhanced the eosinophil-mediated differentiation of airway macrophages toward the alternatively activated macrophage phenotype in an IL-13–dependent manner. Taken together, this study demonstrates that the IL-33/ST2 signaling pathway activates airway eosinophils that exacerbate airway inflammation in an autocrine and paracrine manner.
N-Ethyl-N-Nitrosourea–Induced Mutation in Ubiquitin-Specific Peptidase 18 Causes Hyperactivation of IFN-αβ Signaling and Suppresses STAT4-Induced IFN-γ Production, Resulting in Increased Susceptibility to Salmonella Typhimurium
Authors: Richer Etienne , Prendergast Caitlin , Zhang Dong-Er , Qureshi Salman T. , Vidal Silvia M. , Malo Danielle
Published: August 2010

To deepen our knowledge of the natural host response to pathogens, our team undertook an in vivo screen of mutagenized 129S1 mice with Salmonella Typhimurium. One mutation affecting Salmonella susceptibility was mapped to a region of 1.3 Mb on chromosome 6 that contains 15 protein-coding genes. A missense mutation was identified in the Usp18 (ubiquitin-specific peptidase 18) gene. This mutation results in an increased inflammatory response (IL-6, type 1 IFN) to Salmonella and LPS challenge while paradoxically reducing IFN-γ production during bacterial infection. Increased STAT1 phosphorylation correlated with impaired STAT4 phosphorylation, resulting in overwhelming IL-6 secretion but reduced IFN-γ production during infection. The reduced IFN-γ levels, along with the increased inflammation, rationalize the S. Typhimurium susceptibility in terms of increased bacterial load in target organs and cytokine-induced septic shock and death.
Secondary Immunization Generates Clonally Related Antigen-Specific Plasma Cells and Memory B Cells
Authors: Frölich Daniela , Giesecke Claudia , Mei Henrik E. , Reiter Karin , Daridon Capucine , Lipsky Peter E. , Dörner Thomas
Published: August 2010

Rechallenge with T cell-dependent Ags induces memory B cells to re-enter germinal centers (GCs) and undergo further expansion and differentiation into plasma cells (PCs) and secondary memory B cells. It is currently not known whether the expanded population of memory B cells and PCs generated in secondary GCs are clonally related, nor has the extent of proliferation and somatic hypermutation of their precursors been delineated. In this study, after secondary tetanus toxoid (TT) immunization, TT-specific PCs increased 17- to 80-fold on days 6–7, whereas TT-specific memory B cells peaked (delayed) on day 14 with a 2- to 22-fold increase. Molecular analyses of VHDJH rearrangements of individual cells revealed no major differences of gene usage and CDR3 length between TT-specific PCs and memory B cells, and both contained extensive evidence of somatic hypermutation with a pattern consistent with GC reactions. This analysis identified clonally related TT-specific memory B cells and PCs. Within clusters of clonally related cells, sequences shared a number of mutations but also could contain additional base pair changes. The data indicate that although following secondary immunization PCs can derive from memory B cells without further somatic hypermutation, in some circumstances, likely within GC reactions, asymmetric mutation can occur. These results suggest that after the fate decision to differentiate into secondary memory B cells or PCs, some committed precursors continue to proliferate and mutate their VH genes.
ChemInform Abstract: Band Structure Calculations of Ferromagnetic Chromium Tellurides CrSiTe3 and CrGeTe3.
Authors: SIBERCHICOT B. , JOBIC S. , CARTEAUX V. , GRESSIER P. , OUVRARD G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Crystal Structure, Magnetism, and Phase Transformation in Perovskites A2CrNbO6 (A: Ca, Sr, Ba).
Authors: CHOY J.‐H. , HONG S.‐T. , CHOI K.‐S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Examination of the Corrugated Surfaces of NbTe2 and WTe2 by Scanning Tunneling and Atomic Force Microscopy.
Authors: BENGEL H. , CANTOW H.‐J. , MAGONOV S. N. , JUNG D. , REN J. , WHANGBO M.‐H.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Crystal Structure, Electronic Band Structure, Electrical Resistivity, and Scanning Probe Microscopy Studies of Layered Compound MoOCl2.
Authors: ZOENNCHEN P. , THIELE G. , HESS C. , SCHLENKER C. , BENGEL H. , CANTOW H.‐J. , MAGONOV S. N. , SEO D.‐K. , WHANGBO M.‐H.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pressure Dependence of the Heat of Fusion and Melting Temperature of Indium.
Authors: HOEHNE G. W. H. , DOLLHOPF W. , BLANKENHORN K. , MAYR P. U.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Study of the Phase Transitions in Ba(OH)2, and a Comment on the Fusion of Sr(OH)2.
Authors: CORDFUNKE E. H. P. , BOOIJ A. S. , KONINGS R. J. M. , VAN DER LAAN R. R. , SMIT‐GROEN V. M. , VLAANDEREN P.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electrosynthesis and Electrochemical Behavior of Unusual Solid Thallium‐Based Phases: Thallium Peroxide, Thallium(I)‐Thallium(III) Mixed Oxide, Thallium Cuprate, and Thallium Oxyfluoride.
Authors: TSIRLINA G. A. , PETRII O. A.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stationary Kinetics of Essential Reactions on Automobile Exhaust Pt‐Rh/ Al2O3 Catalyst.
Authors: MANNILA P. , SALMI T. , HAARIO H. , LUOMA M. , HAERKOENEN M. , SOHLO J.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation, Characterization, and Testing of Newly Developed Titania‐ Supported V‐P‐O Catalysts.
Authors: OVERBEEK R. A. , WARRINGA P. A. , CROMBAG M. J. D. , VISSER L. M. , VAN DILLEN A. J. , GEUS J. W.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structural State of Boron in MFI‐Titanium Boralites and Their Catalytic Properties.
Authors: ON D. T. , KAPOOR M. P. , BONNEVIOT L. , KALIAGUINE S. , GABELICA Z.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Investigation of Montmorillonite‐Based Clays in the Preparation of Supported Ferric Nitrate.
Authors: BEKASSY S. , CSERI T. , BODAS Z. , FIGUERAS F.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Microporous Titanium‐Niobium‐Silicates with the Structure of Nenadkevichite.
Authors: ROCHA J. , BRANDAO P. , LIN Z. , KHARLAMOV A. , ANDERSON M. W.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electrochemical Deacetylation of 1,3‐Dicarbonyl Compounds.
Authors: FUJIMOTO K. , MAEKAWA H. , MATSUBARA Y. , NISHIGUCHI I.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Action of Azolium Salts. Part 7. Azolium Salts as Effective Catalysts for Benzoin Condensation and Related Reactions.
Authors: MIYASHITA A. , SUZUKI Y. , KOBAYASHI M. , KURIYAMA N. , HIGASHINO T.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Lipase‐Catalyzed Resolution of Chiral Acids or Alcohols Using Mixed Carboxylic‐Carbonic Anhydrides.
Authors: GUIBE‐JAMPEL E. , CHALECKI Z. , BASSIR M. , GELO‐PUJIC M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reaction of 1,2‐Diketones with N,N‐Dimethylcyanamide in the Presence of Titanium(IV) Chloride.
Authors: MAZIK M. , BOESE R. , SUSTMANN R.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Lanthanum Trifluoromethanesulfonate (La(OTf)3) Promoted Indium‐ Mediated Coupling of Ethyl 4‐Bromocrotonate with Carbonyl Compounds in Water.
Authors: DIANA S.‐C. H. , SIM K.‐Y. , LOH T.‐P.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nitroactivated Double Bonds in Pd(0)‐Catalyzed (3 + 2) Cycloaddition Reactions.
Authors: HOLZAPFEL C. W. , VAN DER MERWE T. L.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Synthetic Method for Perfluorocycloimines.
Authors: NISHIDA M. , FUKAYA H. , ABE T.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Versatile 2‐Fluoroacrylic Building Blocks for the Synthesis of Fluorinated Heterocyclic Compounds.
Authors: SHI G. , WANG Q. , SCHLOSSER M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tandem Transacylation/Debenzylation of β‐Lactones Mediated by FeCl3 Leading to γ‐ and δ‐Lactones: Application to the Synthesis of (‐)‐Grandinolide.
Authors: ZEMRIBO R. , CHAMP M. S. , ROMO D.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Selective and One‐Pot Formation of Phenols by Anodic Oxidation.
Authors: FUJIMOTO K. , TOKUDA Y. , MAEKAWA H. , MATSUBARA Y. , MIZUNO T. , NISHIGUCHI I.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Improved Method for Fluoro‐Dediazoniation of Arylamines Substituted with Polar Groups.
Authors: SASAKI K. , OISHI M. , IMAKI N.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of 1‐Bromo‐ (or 1‐Chloro‐) 1,1‐difluoro‐2‐ alkenes.
Authors: TELLIER F. , SAUVETRE R.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reductive Desulfurization Using the Raney‐Nickel/Sodium Hypophosphite Combination System without Racemization of a Secondary Alcohol.
Authors: NISHIDE K. , SHIGETA Y. , OBATA K. , INOUE T. , NODE M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Reaction of 2,2‐Difluorovinyl Ketones with Amines: A Facile Method for Preparation of α‐Oxoketenimines and Acetoacetylation of Amines.
Authors: ICHIKAWA J. , YOKOTA N. , KOBAYASHI M. , AMANO K. , MINAMI T.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Two Complementary Methods for the Synthesis of the Terminal N‐Alkenyl‐ N‐methylformamide Group Found in Cytotoxic Marine Macrolides.
Authors: PATERSON I. , COWDEN C. , WATSON C.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Raney Co‐Al Alloy, an Efficient Catalyst for the Selective Incorporation of Deuterium Atoms at the Benzylic Position of Aromatic Compounds.
Authors: TSUKINOKI T. , ISHIMOTO K. , MUKUMOTO M. , SUZUKI M. , KAWAJI T. , NAGANO Y. , TSUZUKI H. , MATAKA S. , TASHIRO M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Direct Formation of Organomanganese Bromides Using Rieke Manganese.
Authors: KIM S.‐H. , HANSON M. V. , RIEKE R. D.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organo‐Cerium Reagents in Organic Chemistry: General Method for the Synthesis of Alkyl‐Substituted 1,3‐Diols by RLi‐CeCl3 Addition to . beta.‐Hydroxyketones.
Authors: BARTOLI G. , BOSCO M. , VAN BEEK J. , SAMBRI L. , MARCANTONI E.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral Tricarbonyl(η6arene)chromium(0) Complexes in Stereoselective Hetero Diels‐Alder Reactions.
Authors: BALDOLI C. , DEL BUTTERO P. , DI CIOLO M. , MAIORANA S. , PAPAGNI A.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cuprates as Selective Metalating Reagents for Aromatic Halides.
Authors: KONDO Y. , MATSUDAIRA T. , SATO J. , MURATA N. , SAKAMOTO T.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tosylhydrazines by the Reduction of Tosylhydrazones with Triethylsilane in Trifluoroacetic Acid.
Authors: WU P.‐L. , PENG S.‐Y. , MAGRATH J.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of anti‐1,3‐Diols via Allylboration.
Authors: KABALKA G. W. , NARAYANA C. , REDDY N. K.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 1,1‐Dibromo‐3‐hydroxyalkanes via Opening of Cyclic Sulfates.
Authors: STIASNY H. C.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mononitroalkylations of Butane‐2,3‐dione.
Authors: PITACCO G. , PIZZIOLI A. , VALENTIN E.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Enantiomerically Pure Anti‐Aldols: A Highly Stereoselective Ester‐Derived Titanium Enolate Aldol Reaction.
Authors: GHOSH A. K. , ONISHI M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel One‐Pot Synthesis of Substituted 1,3‐Butadiene‐1‐sulfonyl Chlorides from 3‐Sulfolenes.
Authors: LEE Y. S. , RYU E. K. , YUN K.‐Y. , KIM Y. H.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Inadvertent Synthesis of Cyclic and Acyclic Trithiocarbonates under Phase‐Transfer Conditions.
Authors: RAM V. J. , SINGH S. K. , NATH M. , SRIVASTAVA P.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Synthesis of the Cyclopentene Segment of Queuosine.
Authors: TANAKA K. , OGASAWARA K.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: S‐Nitrosation of Proteins by N‐Methyl‐N‐nitrosoanilines.
Authors: GUO Z. , MCGILL A. , YU L. , LI J. , RAMIREZ J. , WANG P. G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: “Vinylogues” and “Acetylenylogues” of β‐Adrenergic Agents.
Authors: NUDELMAN A. , BINNES Y. , SHMUELI‐BROIDE N. , ODESSA Y. , HIEBLE J. P. , SULPIZIO A. C.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ruthenium‐Catalyzed Addition of Aromatic Imines at the ortho C‐H Bonds to Olefins.
Authors: KAKIUCHI F. , YAMAUCHI M. , CHATANI N. , MURAI S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convenient Synthesis of α‐Alkoxycarbonyl‐α,β‐ unsaturated Trifluoromethyl Ketones.
Authors: KATSUYAMA I. , FUNABIKI K. , MATSUI M. , MURAMATSU H. , SHIBATA K.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Pummerer‐Type Rearrangement of γ‐Fluoro‐β‐ enaminosulfoxides: Efficient Approach to Chiral Non‐Racemic α,. alpha.‐N,S‐Disubstituted Ketals of β‐Fluoro‐pyruvaldehydes.
Authors: BRAVO P. , CRUCIANELLI M. , FRONZA G. , ZANDA M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Anticholinesterase Activity and Antagonism to Calcium Ions of Esters of N‐Substituted Carbamic Acid
Authors: IVANOV YU. YA. , SMIRNOVA N. M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.