bluuebunny/crossref_metadata_2025 huggingface dataset:
Laboratorio Académico Objetar, un modelo de educación superior para Mercadotecnia y Publicidad
Authors: Rucabado Sergi
Published: July 2023

El propósito de este trabajo es describir el proceso de diseño emprendido en la clase de Crítica del diseño de quinto semestre con los alumnos de la licenciatura en Mercadotecnia y publicidad en CENTRO, institución de educación superior afincada en la Ciudad de México. Como parte del modelo de trabajo se implementó un taller durante tres semestres (agosto–diciembre 2014, agosto–diciembre 2015 y agosto–diciembre 2016), experiencia en la cual participaron 49 estudiantes. Los participantes aplicaron el proceso de diseño para buscar y proyectar soluciones creativas concretadas en objetos conceptualmente críticos e ingeniosos.
Managerial Performance Improvement Strategy Based on Budget Participation
Authors: Santoso Aprih , Nugroho Andre S
Published: July 2023

Regional autonomy has led to the decentralization of health services. The impact of the decentralization of health services is the emergence of differences between provinces and districts/cities in terms of the status of funding sources and changes in the structure of the health system in the regions. The main purpose of this study is to examine the relationship between budgetary participation and managerial performance in a public sector organization. It also attempts to examine whether organizational commitment and perception of innovation mediate the budgetary participation and performance relationship. As one of the government-owned public sector organizations in charge of health issues, Semarang City Health Office became the public spotlight regarding budget and performance. The study was conducted at Semarang City's Health Office, and all of the Public Health Centers, the sample size used is 60 echelon officers, using path analysis. The analysis results indicate that Budgetary participation affects managerial performance via the mediating variable of organizational commitment but not perception of innovation. There is a direct relationship between budgetary participation, managerial performance, organizational commitment, and perception of innovation
 
Keywords: Budgetary, managerial performance, commitment, innovation, public sector.
JEL Classification: H51, H61, R10
Review of Dietary Soy's Effects on Human Health and Its Constituents
Authors: Sheneni Victor Duniya
Published: July 2023

Soy protein is a natural component of soybeans and is known to provide a variety of health advantages. It offers advantages and is a different source of protein for folks who don’t consume meat. The purpose of this review is to familiarize readers with the value of soy beans in both the food and medical industries. Legumes, which also include peanuts, chickpeas, various beans and pulses, contain soybeans. Soybeans are incredibly flexible because they can be made into meal, flour and oil. Soy protein has roughly 25 g of approved health claims per day, which is known to lower total cholesterol and LDL. Soy has a variety of powerful ingredients, including fiber, isoflavones, phytic acid, saponins and trypsin inhibitors. Soy has been seen to have several harmful consequences. Numerous studies have raised concerns about the potential negative effects of it because of the allergens present and the antinutrient agents they contain, which prevent micronutrient absorption. It may also result in hypothyroidism because it lacks some essential amino acids, making it a source of incomplete protein. Additionally, it might have hormonal effects on infants later in life.
Comparative Assessment of Salivary Level of Cortisol, Anxiety and Depression in Patients with Oral Conditions: A Case Control Study
Authors: Ankit Kumar
Published: July 2023

Introduction: Cortisol, as the main human glucocorticoid, is considered to be a biological marker of stress and anxiety. It is suggested that stress with its presumed effects on the immune system, constitutes one of the major causative agents for oral mucosal alterations.

Methodology: To enable the study of gender-based differences in stress, salivary alpha-amylase levels and oral lesions, an equal gender distribution was guaranteed. The individuals were then given a clinical examination to look for oral mucosal alterations caused by stress, such as recurrent aphthous ulcers, oral lichen planus, dry mouth and burning mouth syndrome. To identify Temporomandibular Joint Disorders (TMDs), which are also linked to stress, trigger points, masticatory muscles and TMJs were examined.

Results: 80 participants made up the research team, ranging in age from 24-47 years for the experimental group and 27-50 years for the control group. There was an equal number of men and women in both groups. The investigation group’s average age was 33.70 years, compared to 31.93 years for the control group (p=0.16). The study group’s female participants exhibited stress levels that ranged from 5% (N=1) for light stress to 40% (N=8) for severe stress (p=0.10).

Conclusion: However, there was no connection between oral alterations and salivary alpha-amylase.
Artificial Intelligence Systems for Diabetic Retinopathy Screening: Appraisal on the 3rd US FDA Approved Algorithms- AEYE-DS
Authors: Lik Au Sunny Chi
Published: July 2023

Artificial Intelligence (AI) has revolutionized the field of healthcare in recent years, and one of its most promising applications is on the interpretation of medical images [1]. In ophthalmology, the first success comes to the screening and diagnosis of Diabetic Retinopathy (DR) [2]. DR is a common complication of Diabetes Mellitus (DM) that affects the eyes, and early detection and treatment is crucial in preventing vision loss, especially over the working populations [3]. The use of AI in DR screening involves analyzing digital fundus images to detect any signs of DR, including microaneurysms, dot and blot haemorrhages, cotton-wool spots, venous beading, intraretinal microvascular anomalies [4]. Currently, there are 3 US FDA approved systems on DR screening, IDx-DR (Digital Diagnostics), EyeArt (Eyenuk, Inc) and AEYE-DS (AEYE Health, Inc) [5-7]. AI has several advantages over traditional screening methods, including usage by non-ophthalmologically trained medical personnel, accessible and stable performance over whatever time and place, increased speed of clinical workflow, these might potentially help to improve outcomes for patients with DM. In the era of rapidly advancing technology, the use of AI in ophthalmology is an exciting development that might transform our future practice [8]. In this appraisal, we focus on the 3rd US FDA approved AI algorithms for DR.
Validity, Reliability, and Concordance of the Duolingo English Test
Authors: Ye Feifei
Published: July 2023

Duolingo has developed a computer adaptive test of English competency for non-native English learners. This research study of the validity and reliability of the Duolingo English Test was independently conducted from February-April of 2014. The study lasted for approximately eight weeks. Participants were recruited from Duolingo users who studied English, international students in several United States universities, and people who took Test of English as Foreign Language (TOEFL) at several TOEFL centers in China. Participants were at least 18 years of age and had taken the TOEFL within the last 18 months. Participants filled out a survey in the beginning of the study to provide information of their demographics such as age, gender, native language, and education background, experience in learning English, and most importantly, the date and location of taking the TOEFL iBT as well al their TOEFL scores. The participants were directed to complete the Duolingo English Test at the end of the survey. Two weeks later, the participants were instructed via email to fill out a second survey and the Duolingo English Test for the second time. Main results: • Participants’ scores on the Duolingo English Test correlated substantially with their TOEFL total scores, and moderately with TOEFL section scores, with higher correlations for the TOEFL Speaking and Writing sections. This provides criterionrelated evidence of validity of the Duolingo test scores. • Participants’ scores on the first Duolingo English Test correlated highly with their scores on a second test two weeks later, indicating that Duolingo test scores are reliable with a good test-retest reliability coefficient. • Duolingo English Test scores were linked with TOEFL total scores to find the comparable scores from the two tests that have similar percentile rank. Duolingo English Test scores are on a scale of 0–100 and TOEFL scores are on a scale of 0–120. For international students to apply for studying in US universities, the minimum cut-off score of TOEFL iBT is 80 and a more selective cut-off score is 100, corresponding to scores 50 and 72 respectively on the Duolingo English Test.
Generalized Topological Operator Theory in Generalized Topological Spaces: Part I. Generalized Interior and Generalized Closure
Authors: KHODABOCUS Mohammad Irshad , SOOKIA Noor-ul-hacq
Published: July 2023

In a generalized topological space Tg = (Ω, Tg ) (Tg -space), various ordinary topological operators (Tg -operators), namely, int_g, cl_g, ext_g, fr_g, der_g,

cod_g : P (Ω) −→ P (Ω) (T_g-interior, T_g-closure, T_g-exterior, T_g-frontier, T_g-derived, T_g-coderived operators), are defined in terms of ordinary sets (T_g-sets). Accordingly, generalized T_g-operators (g-T_g-operators), namely, g-Int_g, g-Cl_g, g-Ext_g, g-Fr_g, g-Der_g, g-Cod_g : P (Ω) −→ P (Ω) (g-T_g-interior,

g-T_g-closure, g-T_g-exterior, g-T_g-frontier, g-T_g-derived, g-T_g-coderived operators) may be defined in terms of generalized T_g-sets (g-T_g-sets), thereby making g-T_g-operators theory in T_g-spaces an interesting subject of inquiry. In this paper, we present the definitions and the essential properties of the

g-T_g-interior and g-T_g-closure operators g-Int_g , g-Cl_g : P (Ω) −→ P (Ω), respectively, in terms of a new class of g-T_g-sets which we studied earlier. The outstanding results to which the study has led to are: Firstly, (g-Int_g, g-Cl_g) : P (Ω) × P (Ω) −→ P (Ω) × P (Ω) is (Ω, ∅)-grounded, (expansive, non-expansive),

(idempotent, idempotent) and (∩, ∪)-additive. Secondly, g-Int_g : P (Ω) −→ P (Ω) is finer (or, larger, stronger than int_g : P (Ω) −→ P (Ω) and g-Cl_g : P (Ω) −→ P (Ω) is coarser (or, smaller, weaker) than cl_g : P (Ω) −→ P (Ω). The elements supporting these facts are reported therein as sources of inspiration for more generalized

operations.
Tratamentos alternativos aos convencionais com solução fisiológica ozonizada em fêmeas bovinas lactantes com endometrite clínica puerperal
Authors:   , Campos Júnior Leonardo José
Published: July 2023

A ozonioterapia é uma técnica que se baseia na utilização do ozônio como agente terapêutico, para infecções fúngicas, bacterianas e virais. Levando em consideração animais de produção, a terapêutica enfrenta dois grandes desafios: a resistência a antimicrobianos e o elevado período de carência para os resíduos desses fármacos nos produtos de origem animal. Buscam-se, diante desses obstáculos, tratamentos alternativos, sendo um deles a solução fisiológica ozonizada. No presente estudo, foram randomizados 67 animais, de 3 fazendas distintas, positivos para endometrite, em 5 grupos: Tratados com lavado uterino com solução fisiológica a 0,9 % NaCl (SF; n=15), tratados com lavado uterino com solução fisiológica ozonizada (SFOz; n=13), tratados com lavado uterino com solução fisiológica ozonizada e infusão uterina de cloridrato de oxitetraciclina (SFOz+ATBi; n=13), tratados com lavado uterino com solução fisiológica e infusão uterina de cloridrato de oxitetraciclina (SF+ATBi; n=13) e, por fim, tratados exclusivamente infusão uterina de cloridrato de oxitetraciclina (ATBi; n=13). Imediatamente após o tratamento, as vacas foram submetidas ao protocolo de inseminação artificial em tempo fixo (IATF). O tratamento com SFOz e SFOz+ATBi não apresentou diferenças (P>0,05) em relação à taxa de concepção e a taxa de animais curados, quando comparados com os outros tratamentos convencionais; já a SF se mostrou menos eficaz em relação a taxa de animais recuperados, quando comparado com o ATBi (P<0,05). Já a taxa de concepção ao final das 3 inseminações consecutivas ao tratamento foi diferente (P<0,05), onde a fazenda B foi mais eficiente que a fazenda A e C. Já na cura clínica final, foi mais eficiente na fazenda A e B em relação a fazenda C. Houve correlação quanto à classificação ultrassonográfica em cruzes com o padrão ouro de diagnóstico, a percentagem de polimorfonucleares no exame citológico do útero (r=0,50). Em conclusão, o tratamento com solução fisiológica ozonizada se apresentou como uma boa alternativa ao tratamento para endometrite, mostrando eficácia semelhante aos tratamentos convencionais, podendo ser empregado em substituição aos antibióticos. Entretanto, o uso da solução fisiológica não associada ao uso de antibióticos ou soluções oxidativas pode apresentar baixa eficácia no tratamento de endometrite. Além disso, o manejo no qual os rebanhos são submetidos influência de forma significante na resposta ao tratamento. Palavras-chave: Bovinocultura de leite. Metrite. Ozonioterapia.
SOVET HOKIMIYATINING QORAQALPOG‘ISTON ASSRDA IJTIMOIY TA’MINOT SIYOSATI
Authors: Siddiqov Mirshod
Published: July 2023

Ikkinchi jahon urushining dastlabki kunlaridanoq Qoraqalpog‘iston ASSR xalqi front va front orqasida faol ishtirok etib, qahramonlarcha jang qildilar. Urushdan keyingi davrlarda jang harakatlarida jarohatlangan nogironlarni ijtimoiy jihatdan muhofaza qilish uchun ko‘plab muhim ishlar amalga oshirildi. Mazkur maqolada jang maydonlarida qahramonlarcha kurashib, o‘z jonini ayamagan mard, jasur qoraqalpog‘istonlik askarlarning oila a’zolariga ko‘rsatilgan g‘amxo‘rlik,  ularning moddiy ta’minotiga e’tibor, pensiya va nafaqalar bilan ta’minlash, ishga joylashtirish, muhtoj oilalar uchun sanoat mollari ajratilib, uylarini remont qilish, o‘tin-ko‘mir berish va boshqa shu kabi holatlar tahlil qilingan.
TURISTIK KORXONALAR DOIRASIDA TADBIRKORLIK FAOLIYATINI TASHKIL ETISH VA RIVOJLANTIRISHNING IQTISODIY ASOSLARI
Authors: Umronov Eldorbek
Published: July 2023

Maqolada turistik korxonalarda tadbirkorlik faoliyatini baholashda uning turlicha yondashuvlari, kurashini baholash va raqobat nazariyasini tahlil qilish ushbu tadbirkorlik subyektlarining raqobatbardoshligiga ta’sir qiluvchi quyidagi muhim holatlar o‘rganilgan. Tadqiqot jarayonida turistik korxonalarda tadbirkorlik faoliyatini baholashda raqobatbardoshlikning ichki va tashqi omillari, raqobatbardoshlikni baholashga yondashuvlar tadqiqotlar asosida muallif tomonidan shakllantirilgan va asoslangan.
ЗАРУБЕЖНЫЙ ОПЫТ И НАПРАВЛЕНИЯ МЕНЕДЖМЕНТА В РАЗВИТИИ МОЛОДЁЖНОГО ТУРИЗМА
Authors: Норбоев Аллаёр , Тулкинов Гайрат
Published: July 2023

В данной статье рассматривается проводимая в Узбекистане работа по всестороннему развитию и поддержке туризма, существующие проблемы в туризме нашей страны и возможности их эффективного решения. Обращено внимание на необходимость привлечения молодёжи к внутреннему и внешнему туризму с целью ведения здорового образа жизни, а также состояние и развитие молодёжного туризма.
YANGI O‘ZBEKISTONDA IJTIMOIY DAVLAT BARPO ETISH VA UNING G‘OYAVIY MAFKURAGA ASOSLARI
Authors: Ismatov Shohruhbek
Published: July 2023

Yangi O‘zbekistonda erkin fuqarolik jamiyati yanada rivojlantirish va ma’rifatparvar davlat barpo etish yo‘lida keng ko‘lamli islohotlar amalga oshirilmoqda. Mazkur maqolada Yangi O‘zbekistonning 2022–2026 yillarga mo‘ljallangan taraqqiyot strategiyasida “Davlat xalqqa xizmat ko‘rsatishi shart” g‘oyasini tatbiq etish, “Xalqchil davlat” milliy dasturini ishlab chiqilishi, “Xalq bilan muloqotning samarali mexanizmlarini takomillashtirish”, “Inson, uning huquqlari, erkinliklari, ayniqsa, qadri – eng muhim qadriyat” degan tamoyil asosida amalga oshirilayotgan islohotlar tahlil etilgan.
UYG‘ONISH DAVRI DUNYOQARASHIDA DINIY VA DUNYOVIY YONDASHUVLAR NISBATI
Authors: Islamov Kamol
Published: July 2023

Maqolada Uyg‘onish davri dunyoqarashida diniy va dunyoviy yondashuvlar nisbati ilmiy jihatdan tahlil qilindi. O‘rta asrlarda din G‘arbda ham, Sharqda ham feodal jamiyatning hukmron mafkurasi hisoblangan. Bu davrda cherkov eng yirik kuch bo‘lgan. Teotsentrizm, ya’ni Xudoga, uning mohiyatiga dunyoning birinchi sababi va birinchi asosi sifatida yondashish o‘rta asrlar falsafasiga xos xususiyat ekanligi maqolada asoslab berilgan.
AMIR TEMUR VA TEMURIY HUKMDORLAR YORLIQLARIDA SIYOSIY NUTQ SHAKLLARINING QO‘LLANILISHI
Authors: Ro‘ziyev Elbek
Published: July 2023

Ushbu maqolada ijtimoiy-siyosiy nutqning tarkibiy qismi hisoblangan yorliqlar matnidagi siyosiy nutqning lingvistik xususiyatlari tahliliga ahamiyat qaratilgan. Amir Temurning To‘xtamishxonga qarshi yurish boshlagan paytda qoyaga yozilgan bitigi, Xorazmdagi Abu Muslim avlodlari haq-huquqlarini himoya qilishga qaratilgan turkiy (eski o‘zbek) bitigi hamda Shohruh mirzoning turkiy tildagi yorliqlarining matn xususiyatlari va ularda ifodalangan siyosiy matnning o‘ziga xosligiga e’tibor qaratilgan.
TILSHUNOSLIKDA SO‘Z VA SO‘Z TURKUMLARI: TADQIQI VA TAVSIFI
Authors: Abdullayev Ikramjon
Published: July 2023

Ushbu maqola tilshunoslik fani sohasida so‘z va so‘z turkumlari tasnifi, ularning grammatik va leksik jihatlardan tahlili hamda o‘rganish usullari haqida. Maqolada so‘z va so‘z turkumlari tushunchasi ochib beriladi, ularning asosiy xususiyatlari, funksiyasi va ahamiyati haqida ma'lumot beriladi. So‘zlar va so‘z turkumlari grammatik tasnifi, leksikografiyada turli usullar yordamida o‘rganiladi. So‘zlar ma'nolilik, jamlanish, qo‘llanilish darajasi va boshqa tarzda, so‘z turkumlari esa qandaylik asosida tasniflanganligi ko‘rsatiladi.
MADANIYATLARARO MULOQOTDA NUTQIY ETIKETNING ANTROPOSENTRIK TADQIQI
Authors: Egamberdiyeva Mohidil
Published: July 2023

Mazkur maqola muloqot jarayonida madaniyatning ahamiyati, ingliz va o‘zbeklarning nutqiy etikasi shakllanish jarayoniga ta’sir etuvchi omillarni atroflicha tahlil etadi. Shuningdek, madaniyat, nutq, etika va antroposentrik tadqiq tushunchalariga ta’rif berib, ularning matn ichida tushunilish hazmini osonlashtiradi. Ushbu tahlil til va madaniyatning muloqot yuzaga kelishida asosiy omil ekanligini ko‘rsatadi. Turli madaniyat vakillarining o‘z nutqiy etikasini rivojlantirishida bir-biri bilan o‘zaro aloqa qilishi negizida madaniyatlararo muloqotning kengayishi yotadi.
МАЪМУРИЙ-ҲУҚУҚИЙ НИЗОЛАР ТУШУНЧАСИ ВА МАЗМУН-МОҲИЯТИ
Authors: Жавлиев Нурали
Published: July 2023

Ушбу мақолада маъмурий-ҳуқуқий низо тушунчаси, унинг ўзига хос жиҳатлари ва зарурий белгилари ўрганилган. Бунда маъмурий-ҳуқуқий низо маъмурий иш, юридик конфликт ва юридик коллизия каби илмий категориялар билан ўзаро нисбатда таҳлил қилинган. Мақолада етакчи олимларнинг нуқтаи-назарлари ҳамда амалдаги қонунчилик тадқиқ этилиб, маъмурий-ҳуқуқий низонинг муаллифлик таърифи таклиф этилган.
БАРҚАРОР РИВОЖЛАНИШ МАҚСАДЛАРИГА ЭРИШИШДА СУВ РЕСУРСЛАРИДАН ОҚИЛОНА ФОЙДАЛАНИШ (ҲУҚУҚИЙ ЖИҲАТЛАРИ)
Authors: Узакова Гўзал
Published: July 2023

Мақолада БМТ Барқарор ривожланиш дастурида белгиланган асосий мақсадлардан бири бўлган – аҳоли учун  тоза сув ва санитариянинг мавжудлигини таъминлашнинг ҳуқуқий жиҳатлари таҳлил қилинган. Муаллиф Ўзбекистон Республикасининг сув қонунчилиги ҳолати, унда ифодаланган сув муҳофаза зоналари режими, сув истеъмоли ва сувдан фойдаланиш ҳуқуқлари, ер ости сувларидан фойдаланишнинг амалдаги ҳуқуқий режимини ўрганган.
BO‘LAJAK VOKAL O‘QITUVCHILARINING INTELLEKTUAL- IJODIY FIKRLASH QOBILIYATINI RIVOJLANTIRISH
Authors: Rajabiy Aziz
Published: July 2023

Mazkur maqola bo‘lajak vokalistlarning ijodiy tasavvurini rivojlantirish uslublariga bag‘ishlangan bo‘lib, yetakchi sahna ustalarining ijodiy uslublari va psixologlarning nazariy ishlanmalari asosida muallif quyidagi xulosalarga to‘xtaladi: ijro etilayotgan asar sifati obrazli umumlashma yaratish talabaning sezgi, his-tuyg‘ulari, ilhomi, badiiy didiga asoslanadi; obrazli tasavvur darajasi ijrochining belgilangan sifatlariga to‘g‘ridan-to‘g‘ri proporsional bo‘lib, tasavvur aqliy jarayon sifatida tafakkur va xotira bilan chambarchas bog‘liq; faoliyatning ajralmas qismi hamda  ijodiy fikrlashni faollashtirishning muhim sharti bu maxsus kayfiyat hisoblanadi.
BO‘LAJAK XOR RAHBARLARINING IJODIY QOBILIYATLARINI RIVOJLANTIRISH
Authors: Malikova Sevar
Published: July 2023

Mazkur maqolada bo‘lajak xor sinfi o‘qituvchilarining ijodiy qobiliyatlarini rivojlantirishning zaruriyati, usul va vositalari bayon etiladi. Shuningdek mazkur muammoni tadqiq etgan olimlar fikrlari tahlil etiladi.
ТЕХНОЛОГИИ РАЗВИТИЯ ВОКАЛЬНО-ХОРОВЫХ НАВЫКОВ
Authors: Васильченко Ольга
Published: July 2023

В статье освещается инновационная методика проведения хоровых дисциплин, раскрывается использование новых технологий в вокально-хоровом разделе урока в виде элементов хорового сольфеджио, предлагаются технологические приемы освоение навыков многоголосия.
BO‘LAJAK JISMONIY MADANIYAT MUTAXASSISLARINING PEDAGOGIK MADANIYATI VA KOMPETENSIYASINI TAKOMILLASHTIRISHNING PEDAGOGIK MODELI
Authors: Mamadova Feruzaxon
Published: July 2023

Maqolada bo‘lajak jismoniy madaniyat mutaxassislarining pedagogik madaniyati va kompetensiyasini takomillashtirishning pedagogik modeli, pedagogik faoliyat, qobiliyat darajalari haqida so‘z yuritilgan.
BO‘LAJAK JURNALISTLARGA INGLIZ TILINI O‘QITISHDA SOTSIOLINGVISTIK KOMPETENSIYANI TAKOMILLASHTIRISH (SIYOSIY-IJTIMOIY MATNLAR MISOLIDA)
Authors: O‘ktamova Navruza
Published: July 2023

Mazkur maqola bo‘lajak jurnalistlarning sotsiolingvistik mahoratini rivojlantirish, sotsiolingvistik mahorat qismlarini - ma'lum bir tuzilmani ma'lum ijtimoiy iqlim va ustun ijtimoiy va ochiq muhitga bog‘liq bo‘lgan individual nutq xatti-harakatlariga majburlaydigan sotsiolingvistik dunyoqarashni tayyorlash va tugatishga qaratilgan. Jurnalistlarning sotsiolingvistik mahoratini oshirishga tayyorgarlik asoslari o‘quv va uslubiy me'yorlarga asoslanishi, noodatiy sotsiolingvistik mazmun bilan takomillashtirilishi kerakligi, bu esa jurnalistlarning o‘z nutqlarini o‘zlashtirishga bog‘liq bo‘lgan ma'lumotlari, qobiliyatlari va imkoniyatlarini yaxshilash uchun sabab ekanligi ko‘rsatilgan.
PRОFESSIОNAL TA’LIM TIZIMINI TAKОMILLASHTIRISH YUZASIDAN ISLОHОTLARNI JADALLASHTIRISH VA KASBIY KО‘NIKMALARNI RIVОJLANTIRISH
Authors: Xuramоv Ilxоm
Published: July 2023

Maqоlada prоfessiоnal ta’lim tizimini takоmillashtirishda islоhоtlarni jadallashtirish hamdabо‘lajak mutaxassislarda kasbiy kо‘nikmalarni rivоjlantirishda xоrijiy tajribalarni о‘rganish, prоfessiоnal ta’lim muassasalari bо‘lgan vazirlik va idоralarga berilishi kо‘zda tutilayоtgan huquqlar va ulardan kutilayоtgan natijalar bayоn etilgan.
Effects of tibiofemoral mobilization in patients of Patellofemoral pain syndrome
Authors: Ishrat Fatimah  , Saira Waqqar
Published: July 2023

Objective: To determine the effects of tibiofemoral joint mobilization on pain and Range of motion in patient with patellofemoral pain syndrome.
Methods: This randomized control trial was conducted at Lady Reading Hospital and Hayatabad Medical Complex in Peshawar from July 2019 to August 2019. Total 52 participants of both gender were selected, who met inclusion criteria of age 25 to 35 years, anterior knee pain of at least one month. They were randomly allocated through sealed envelope method. Control group received specific 6 exercises of hip and knee with conventional treatment while experimental group received PFJ mobilization prior to same exercises advised to control group. Numeric pain rating scale, Kujala Anterior Knee Pain Scale, Algometer and Goniometer were outcomes measuring tools used to take measurements at baseline and after every 3rd session i.e. 3 sessions per week in 4 weeks.
Results: This study stated that Experimental group showed more improvement in pain on Numerical Pain Rating Scale, ROM, Pressure Pain Threshold (PPT) and Type of Pain. According to Kujala Anterior knee pain score Experimental group indicated significant improvement in daily activities i.e. limping, weight bearing, walking, squatting, stairs climbing, squatting, running and jumping.
Conclusion: This study concluded that TFJ mobilizations prior to hip and knee exercises were more effective in terms of ROM, Type of pain and pressure pain threshold than exercises of hip and knee joint
Clinical Trial Number: Identifier: NCT04225000
Continuous...
Myths and Facts about Diet (Ahaar) in Today’s Era
Authors: Kusum  , Singh Satnam
Published: July 2023

In Ayurveda, diet has been given a great importance and is referred as Mahabhaisjaya in Ayurveda classics. Bhaisjaya means medicine or any substance that cure body, means diet is not only to satisfy hunger of Ahaara, but it also acts as medicine i.e., build and cure the body. The distinction between health and disease is correlated with wholesome and unwholesome diet because both body and disease are the product of food. There is urgent need to have knowledge about real facts and burst myths about food items. Ayurveda has its own unique approach to Planning a daily diet for an individual. It is not based on conventional chemistry; rather, it is based on Panchmahabhautic chemistry and Tridoshic functions. In Ayurveda, Annapanavidhi can be correlated with dietetics. It incorporates the concept of Pathya-Apathya, the natural characteristics of different food items and the dietary guidelines which leads towards sound health. According to Ayurvedic classics One type of food can’t be benefited for different type of people. There are many variations like Prakriti, Desh, Kaal, Agni etc. Digestion of Ahara and Poshan by Ahara is based on many factors. It’s not like modern science reduced to calories or in term of carbohydrates, proteins, fats etc. only. Unhealthy diet practice is considered as one of the important reasons of disease. Hence the correction of diet itself is considered as treatment. Without this knowledge our food is worthless even after we consume a very high-quality food. So, there is an effort to put some light on facts and myths about food in today lifestyle by this paper.
A Randomised Control Trial comparing the efficacy of Jati Ghrita and 1% Chlorhexidine Gluconate on Aphthous Stomatitis
Authors: Ranit Pranoti , Meshram Mrunal , Rathi Renu , Devyani Taori  , Priyanka Paul Madhu  , Reche Amit
Published: July 2023

Background:  Aphthous ulcer is seen to be one of the most commonly occurring ailments found among patients that dentists may come across on a daily basis. Taking into consideration the agents that have been used for treatment of aphthous stomatitis, it would seem advisable to apply the agent that is the safest and has the least toxic properties that can bring about symptomatic relief and that can be applied topically. These days, there are few reliable natural remedies that are emerging as a therapy for aphthae. Herbal and polyherbal medicines will alleviate pain, induce healing, prevent infection, and lessen inflammation in aphthous ulcers without any adverse effects. Aim:  To evaluate the efficacy of Jati Ghrita and 1% chlorhexidine gluconate and its comparison on aphthous stomatitis patients.Materials and methods: A randomized control trial is carried out in the Department of Oral Medicine and Radiology, Sharad Pawar Dental College and Dattatray Ayurvedic Rasashala.The study population consisting of 30 patients with Aphthous stomatitis is divided randomly into two groups i.e.,Jati Ghrita and 1% Chlorhexidine gluconate, each group consisting of 15 patients.The intergroup comparison is done by independent sample t test. Results: Jati Ghrita is found to be effective in faster healing of aphthous stomatitis with reduction in pain. Jati is found to be more effective than 1% chlorhexidine gluconate. Conclusion: Jati has good medicinal properties and ghee accelerates wound healing so combination of this was found to be effective for treating aphthous ulcers. It is advised to use these natural treatments in place of conventional medicine method in the treatment of recurrent aphthous stomatitis due to the affordability, accessibility, and lack of potential side effects of these herbal treatments.
Evaluation of comparative efficacy of Dietary supplement acquired from Kitchen Garden (Parasbag) and Gudharitaki Awaleha in Pandu Roga (Iron Deficiency Anemia)
Authors: Misar Wajpeyi Sadhana , Badwaik Premkumar
Published: July 2023

Backround-Panduroga is a Raktapradoshaja vyadhi having pitta dominance. Due to similarity of symptoms it can be correlated with Iron deficiency Anemia. Iron deficiency anemia secondary to inadequate dietary iron intake is caused by consuming a diet low in iron-rich foods. The richest sources of minerals and vitamins are fruits and green leafy vegetables.  Growing a variety of crops in the kitchen garden is one of the simplest methods to make sure that everyone has access to a balanced meal that contains enough micronutrients. Aim and objectives-The objective of this study, which is being conducted in association with Mission Samriddhi (MS), is to compare the effectiveness of dietary supplements from Kitchen Garden (Parasbag) and Gudaharitaki Awaleha. Methodology- Total 60 patients were selected and divided in two equal groups. Group A patients were treated with nutritional supplement obtained from (Parasbag) Kitchen Garden along with Gudaharitaki Awaleha whereas group B patients were treated with Gudaharitaki Awaleha for 90 days. Assessment of subjective and objective criteria was done before and after treatment. Result and Discussion- Significant improvement was observed in subjective and objective parameters in both groups. But improvement was observed in more number of patients in group A than group B. Conclusion- Nutritional supplement obtained from (Parasbag) Kitchen Garden and Gudharitaki Awaleha improve Haemoglobin percentage because organically grown vegetables and fruits are rich in nutrients which help in prevention of nutritional deficiencies.
Management of Herpes zoster in Ayurveda through Bloodletting therapy along with other Ayurveda treatment: A case study
Authors: Ashok Jain Dipa , Vasudeo Welankar Vinay , Sarjerao Shirkande Abhijeet , V Changade Jayshree , Abhijeet Shirkande Ankita
Published: July 2023

Herpes zoster is a very painful disease. Generally, it is a unilateral and self-limiting condition. Inappropriate or delayed therapy might make the disease worse and increase the risk of complications such as post-herpetic neuralgia. Age-related immunosuppression and low immunity make people more susceptible to herpes infection and more likely to develop post-herpetic neuralgia (15%). According to Ayurveda, it correlates with visarpa. It is a raktapradoshaj vikara (disease caused by vitiated blood) and primarily a pitta-predominant disease manifesting twaka (skin) so visarpa is one of the major skin diseases. Here we present a case of a 66-year-old female patient with k/c/o HTN and hypothyroidism visited the OPD with symptoms of unilateral onset of blisters on the right side of the back region, the right axillary region, and the medial aspect of the right arm, within 48 hours; along with burning Pain, itching, and sleeplessness due to burning. According to Ayurveda, the patient was clinically diagnosed with pittaj visarpa. Considering pitta dosha and rakta dhatu dusti, raktmokshan was planned as the prime treatment. The patient showed improvement in burning pain after the first setting of raktamokshan. The numeric rating scale revealed that the patient experienced relief in the severity of burning pain (from 8 to 0) and itching (from 5 to 0). Other Ayurveda treatments like pittaghna chikitsa (pitta pacifying) and pradeha (local application) were used. Rapid blister formation stopped within three days of treatment, and after 28 days, all blisters crusted off and a normal skin complexion was achieved. Thus, Ayurvedic treatment was valuable and cost-effective for treating conditions like herpes. Ayurveda protects patient’s immune systems and reduces the chances of post herpetic neuralgia and reinfection.
Molecular docking analysis of selected bioactive components of Glycyrrhiza glabra against bronchial asthma
Authors: E Nandhini , P Chakravarthi , S Kanimozhi , S Mathukumar
Published: July 2023

Bronchial asthma is a chronic inflammatory disease of the lung by the combined action of various cytokines. As a result of the strong inflammatory response increased infiltration of cytokines result, damages respiratory epithelium, Hyperplasia of the trachealis muscle, and increased mucous production. Athimathura choornam is a promising drug used in all inflammatory conditions. Objective:  To explore the efficacy of the Siddha formulation Athimathura choornam, an anti asthmatic drug using computational molecular docking analysis. Method: Based on the phytochemical study the active principles present in the plant Athimathuram were retrieved. 3D structure of the targets were retrieved from the repository and purified before the initiation of docking using the software. The potency of the drug was screened based on the binding of the ligands Asparagine, Liquiritin, and Glabridin with targets mentioned. These results were compared with the standard drugs such as Cetirizine, Salicylic acid, Diclofenac, Ibuprofen, and Celecoxib. Results and Conclusion: Liquiritin has 9 interactions (90%) similar to that of Ibuprofen, 14 interactions (90%) similar to that of  Citrazinehence , 5 interactions (100%) similar to that of salicylic acid hence it has promising COX 1 inhibition ,Histamine 1 blocking activity and Prostaglandin Synthase inhibition activity. Asparagine has 3 interactions (60%) similar to Celecoxib, has promising COX 2 inhibition activity. Glabridin has 2 interactions (50%) similar to that of Diclofenac hence it has promising IL6 inhibition activity.
Management of Uthiravathasuronitham (Rheumatoid arthritis) by Siddha traditional formulation Amirdha Gandhi Kukkil Vallathy – A case series
Authors: L Juliet , S Sivakkumar , C J Christian , Jabaris S Sugin Lal , N Kabilan , K Kanakavalli
Published: July 2023

Aim and Objectives: Rheumatoid arthritis is an auto immune disease and its signs and symptoms are correlated with Uthira vatha Suronitham (UVS) in Siddha. Here we discussed a case series of Rheumatoid arthritis managed by a novel, classical Siddha formulation Amirdha Gandhi Kukkil Vallathy (AGKV). Methods: Three cases were diagnosed as Rheumatoid arthritis (RA) based on ACR/EULAR 2010 criteria, along with symptoms of UVS as per Siddha literature. All the three cases were treated with Siddha medicine AGKV 2 gm bid for 48 days in the General out patients department, Siddha Central Research Institute. Observations: The assessment was made by the signs and symptoms and serological parameters like C-Reactive protein (CRP), Erythrocyte Sedimentation Rate (ESR), Haemoglobin (Hb), Rheumatoid Arthritis factor (RA factor). Results: The RA Factor was reduced in all three patients from 60 to 13.9, from 133 to 106, from 60.7 IU/ml to 35.6 IU/ml ; CRP reduced in case 1 from 135.8 to 34.3, case 3 from 18.9 to  5.6, reduction in RAPS score and clinical symptoms were noticed in all three cases and were followed for 1 year and managed with diet advice. This case series highlights that RA can be successfully managed with Siddha herbo mineral preparation AGKV within a minimum period of 48 days. Hence in a long duration of treatment, it will certainly give good results to reduce the burden of RA patients.
Ayurvedic management of Polycystic Ovarian Disorder - A case study
Authors: Mishra Khushboo , Changade Jayshee , Sonalkar Ashwini D
Published: July 2023

Background: Polycystic ovarian disease (PCOD) is a complex heterogeneous disorder with involvement of endocrinopathies. Ayurveda does not correlate the condition to a single disease or syndrome but the symptoms bears a resemblance to involvement of Vata and Kapha Doshas. Ayurveda treats Poly Cystic Ovarian Disorder by correcting basic disturbances in metabolism, by restoring ovulation naturally by speeding up growth of follicles. The line of treatment for PCOS patient depends on the body constitution of patient, causative factors and symptoms shown. Case report: A 25-years female patient with her husband aged 28 years reported the OPD of Prasuti Tantra evam Streeroga, with the complaints of dysmenorrhoea, scanty menses, delayed menses, acidity, hairfall, and general weakness. Her ultrasonography reports revealed poly cystic like appearance of ovaries. Her menstrual cycle was 2 days/ 45 days, scanty, painful with few clots. Obstetric history was nil. Patient was given Kuberaksha vati, Kalaonji powder, Rasapachak kwatha, Granthiraja powder, and Navayas Churna for 4 months with followup taken every month. Result: After treatment, patients menstrual cycle was set gradually to normal i.e. 28 days. Her interval between menses was reduced. Significant relief was achieved in complaints of dysmenorrhoea and clots. Even her USG findings showed normal appearance of ovaries after treatment. Conclusion: This case supports the importance of personalised medication in management of poly cystic disorder. It also emphasizes the significance of Kuberaksha vati, Kalaonji powder, Rasapachak kwatha, Granthiraja powder, and Navayas Churna in reducing subjective ad objective signs and symptoms of Poly Cystic Ovarian Disorder. Further large scale clinic trial scan be helpful for drawing further conclusions.
A clinical study on the management of Arshas (Prolapsed Piles) by Jaloukavacharana
Authors: T Udaya Kiran , Menon Arya , B K Mugilmathi
Published: July 2023

Background: Arshas is one among the Mahagadas (major diseases) which causes pain and obstruction in the anal passage. It is a rakta and mamsa doshaja vyadhi (disease related to blood and muscle). Arshas can be correlated to hemorrhoids. It is caused due to the varicosity of hemorrhoidal plexus which makes it a surgically curable disease. In Ayurveda, various treatments have been mentioned for the management of arshas (hemorrhoid) such as chedhana (excision), sweda (sudation), etc among which Visravana or raktamokshana (blood-letting therapy) plays an important role. Jalaukavacharana (leech therapy), a type of Asashtra krita Visravana (non-invasive blood-letting) has been mentioned as an alternate, non-surgical measure in the management of arshas (hemorrhoid). The arshas (hemorrhoids) which are swollen, prolapsed and containing more quantum of stagnated blood inside can be managed by leech therapy. The saliva of leech contains an anti-coagulant factor – Hirudin and a spreading factor – Hyaluronidase, which act as anesthetic and anti-inflammatory, thereby helping in the treatment of arshas (hemorrhoid). In the present study, raktamokshana (blood letting) was performed with jalauka or leech in patients with prolapsed pile mass. Materials and method: 30 patients fulfilling the assessment criteria were selected for the study. Result and conclusion: In the present study 26 patients were completely cured, 3 patients were cured with presence of mild symptoms and 1 patient had improvement from severe symptoms to moderate symptoms. Therefore, Jalaukavacharana (leech therapy) can give promising results in the management of prolapsed piles.
An observational study of endometrial vascularity in implantation
Authors: Gambhire Bhadugale Harsha , Tekawade Umesh , Shelar Suvarna , Herlekar Suhas
Published: July 2023

Background: According to Ayurveda, Ambu is one of the four essential factors of Garbhasambhav Samugri for formation and development of the embryo. The word Ambu means nutrients essential for formation and growth of embryo which it receives from mother. According to modern science, during implantation, embryo receives its nutrients from endometrium. Though some women have normal endometrial thickness, normal endometrial pattern, normal endometrial morphology, still they are unable to get impregnated. During peri-implantation period of menstrual cycle, endometrial vascularity has major role in implantation of fertilised egg and also further growth of foetus. Objectives: The objective of this study is to evaluate implantation rates in women having endometrial vascularity upto V1, V2, V3, V4 zones. Material & Methods: Anonymous data of endometrial vascularity by transvaginal colour doppler ultrasound examination done, on the day of rupture of follicle of menstrual cycle, on 160 women, willing to conceive, has been collected from gynaecologist. And also, her status whether she was implanted or not implanted was collected from the gynaecologist. Data about her pregnancy status upto 20 weeks were collected. From this collected data, results regarding endometrial vascularity were derived. Results: Implantation rate in cases having vascularity upto V1 zone, upto V2 zone, upto V3 zone, upto V4 zone were 0 %, 8.33 %, 25 %, 30.5% respectively. Conclusion: Implantation rate is greater in cases having vascularity upto V3 and V4 zone than V1 & V2 zone. Endometrial vascularity is an important factor for implantation of fertilized egg and also for further growth of embryo.
Validation of hospital environmental disinfection efficiency of herbal fumigants
Authors: Tavhare Swagata Dilip , Lakhani Karan
Published: July 2023

Background: Healthcare associated infections includes infestation by bacteria, viruses and fungi. As per WHO estimates, approximately 15% of all hospitalized patients suffer from these nosocomial infections caused by these micro-organisms. Outbreaks of such infections increases the use of antibiotics, vitamins and immonomodulator medicines. During ancient times, to prevent spread of infections; fumigation with herbs was a practice and it is still seen continued. Material & methods: Good quality herbal fumigants like Guggulu gum-resin, turmeric powder, spikenard rhizome, white mustard fruits, caraway fruits, camphor resins and cow’s ghee were used for fumigation of various hospital rooms like out-patient department room, dental clinic, gynecological procedure room, physiotherapy and operation theatre of Community Healthcare Center, Sarsa. Swabs from these units were tested for bacterial and fungal load before and after experiment by using culture media’s like nutrient broth and potato dextrose agar respectively. Results: The bacteria culture reported organisms namely Bacilus subtilis, Bacilus megaterium, Staphylococcus aureus, Micrococcus luteus and fungi like Aspergillus niger, mucor and rhizophus. After 30 minutes of fumigation procedure, significant reduction in bacterial colonies was found in gynecological procedure room, dental clinic, OPD and physiotherapy room while statistically non-significant results were observed in operation theatre. Two hours after fumigation, statistically significant result was observed in bacterial count in all studied units except operation theatre while fungal colonies reduction was achieved in all studied units. Conclusion: Fumigation shall be encouraged in hospital units like out patients department, wards and minor procedure rooms but may not be perfectly suitable for operative theatres always. The study encourages daily herbal fumigation of home and surroundings for hygienic and pleasant environment.
A review on examination of breast milk in Ayurveda and its physicochemical properties with its component
Authors: Wahlang Nishahun , Rathi Renu B
Published: July 2023

Background: Breast milk is the only and complete nutrition supply for infants breastfeeding contains all the necessary elements for healthy baby growth and development. Breast milk contains bioactive agents that help in the proper functioning of the gastrointestinal system which affects the circulatory system. Objectives: The objective is to review recent findings on the different content and components of breast milk from premature and term infants, examination protocol of breast milk, the physicochemical properties of mature breast milk, recent knowledge of the prebiotic and probiotic effect of breast milk through different articles, classical books of Ayurveda then summarized the evidence available. Materials and methods: The information is collected from articles which are from PUBMED, SCOPUS, GOOGLE SCHOLAR, and only classical books of Ayurveda. Observation: The composition of breast milk including protein, carbohydrate, fat, minerals, vitamin, and immunoglobulin contribute to the nutrition and immunity action of breast milk. The composition of breast milk i.e. macronutrients and micronutrients differ at different stages of breast milk including colostrums, transitional and mature milk. The result of physicochemical properties differs according to the methods used for the evaluation of the different physicochemical properties of breast milk but the mean value is taken into consideration. Results: The different parameters in the examination of breast milk as per Ayurveda. The physicochemical properties of breast milk include pH, specific gravity, electrical conductivity, viscosity, water activity, osmolarity, refractive index, freezing point, and surface tension.
An Insilico Computational Screening of Siddha Formulation Kalingathy Thailam against Cyp- 17α-Hydroxylase in PCOS
Authors: G Dhivya , K Bharathy , T Lakshmi Kantham , R Meenakumari
Published: July 2023

Background: PCOS is characterized by ovulatory failure, hirsutism, obesity, glucose intolerance, resistance to insulin, dyslipidemia and infertility. Siddha system of medicine has a worthwhile therapeutic effect in treating PCOS. The bioactive compounds of Kalingathy Thailam mentioned in Siddha literature was selected for evaluating their ability to inhibit CYP- 17α-hydroxylase. Objective:  The study is aimed to perform the In Silico computational screening of the formulation Kalingathy Thailam against the target enzyme CYP-17 α -hydroxylase in PCOS. Methods: Autodock program was used against the target enzyme CYP-17 α -hydroxylase  for the phytocomponents such as Sinapic acid, Cucurbitacin B of Citrullus colocynthis (L. ) Schrader, Aromadendrene, Linolenic acid of Melia dubia Linn. , Onionin A, Protocatechuic acid of Allium cepa Linn. , Ascorbic acid, Limonene of Citrus limon (L. )Burm. f. , Ricinine of Ricinus communis Linn. Results: A total of 9 components were screened, out of these Protocatechuic acid, Ascorbic acid, Linolenic acid and Cucurbitacin B reveals maximum of 2 to 3 interactions accounting for 75-100% binding efficacy with the core active amino acid residues present on the target enzyme CYP- 17α-hydroxylase. Conclusion: Based on the results of the computational analysis it was concluded that the bio-active compounds present in the herbal ingredients possess significant binding against the target enzyme CYP-17α-hydroxylase by interacting with active amino acids. Hence these phytocomponents which inhibit the target enzyme may act as a potential therapeutic agent for management of PCOD.
Plan de estrategias de control, prevención y seguridad ocupacional, para una empresa de construcción
Authors: Cortez Méndez Rodrigo José , Benítez Pincay Lesly Johanna , Valenzuela Velasco Cesar Andrés
Published: July 2023

Las empresas cada día buscan mejorar su rentabilidad, siendo las empresas de la construcción uno de los sectores que más dinamiza la economía de un país- Sin embargo, en ocasiones no se asumen las medidas de seguridad laboral requerida es por ello que esta investigación se planteó como objetivo Caracterizar un plan de estrategias de control, prevención y seguridad ocupacional, para una empresa de construcción. Metodológicamente responde a una investigación de campo bajo el enfoque cuantitativo, la técnica de recolección de datos fue la encuesta aplicada a 30 trabajadores de una empresa de construcción. Como técnica de análisis se empleó la estadística descriptiva. Los resultados expresaron que el 50% de los trabajadores encuestados consideran que no la empresa no tiene organizada la prevención; porque no las conocen o consideran que no son difundidas de manera adecuada, en un 30% consideran que han recibido formación y un 83% han recibido información de los riesgos laborales pero de manera verbal por lo que se concluye considerándose que es necesario un plan de control, prevención y seguridad ocupacional, para una empresa de construcción ajustado a las características propias de la empresa contemplando: información, compromiso y construcción de propuestas.