bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFECT OF AMIODARONE IN PREVENTION OF ATRIAL FIBRILLATION IMMEDIATELY AFTER RELEASE OF AORTIC CROSS-CLAMP
Authors: Sahu Lingaraj , Samantaray Alok , Behera Shashi Sankar
Published: March 2018

Objective: The objective of this study is to determine the efficacy of a bolus dose of amiodarone administered by the way of cardiopulmonary bypass pump before releasing of aortic cross-clamp (ACC) in the prevention of atrial fibrillation.Methods: In this prospective study, 22 non-diabetic patients were randomly assigned in a double-blind fashion to either amiodarone or placebo group. In amiodarone group injection amiodarone 3 mg/kg in 10 ml normal saline (amiodarone group, Group A, n=10) and in control group (control group, Group P, n=12), the same volume of normal saline was administered 3 min before the release of ACC. Initial rhythm after the release of ACC was noted.Results: The major rhythm after the release of ACC was ventricular arrhythmia in control group (n=5, 40%), whereas in amiodarone group, it is normal sinus rhythm (n=7, 63%). Only the need of cardioversion/defibrillation and the amount of energy needed was less in the amiodarone group but not reached statistical significance level. There was a trend toward a higher ventricular rate in control group compared to amiodarone group, but it never reached statistical significance level (114±46 vs. 97±29, p=0.3). One patient in amiodarone group required temporary pacemaker for sustained atrioventricular block with heart rate of <50 beats/min and continued on temporary pacemaker for 48 h.
ANTIDIABETIC EFFECT OF MIKANIA SCANDENS ON ALLOXAN-INDUCED RAT MODEL
Authors: Baishya Rimashree , Adhikari Anjan , Biswas Sharmistha , Banerjee Soma
Published: March 2018

Objective: The objective was to study the evaluation of antidiabetic and antioxidant activity of different doses ethanolic extract of Mikania scandens leaves.Methods: The rats were divided into five groups of six animals each (non-diabetic control, diabetic control, standard drug-treated, and plant treated groups (250 and 500 mg/kg body weight)). Diabetes was induced in the healthy male Wistar rats (150–200 g body weight, 4–6 weeks old) by the administration of alloxan monohydrate (150 mg/kg, i.p.). On the 0th, 3th, 7th, 11th, and 15th days, the blood samples were analyzed for blood glucose. The antioxidant and antidiabetic parameters were evaluated by standard protocol. The liver tissue was used for histopathological assessment of liver damage.Results: The ethanolic extract of leaves of M. scandens showed a significant reduction (p<0.001) in the blood glucose levels and the antioxidant levels, with 500 mg/kg of body weight in the alloxan-induced diabetic rats as compared to the controls. Histopathological studies provided evidence that the leaf extract possesses antidiabetic activity.Conclusions: The ethanolic extract of leaves of M. scandens showed potent antidiabetic and antioxidant abilities against alloxan-induced rats, which indicate the presence of hypoglycemic constituents in the plant.
ELUCIDATION THE TOXICITY MECHANISM OF ZINC OXIDE NANOPARTICLE USING MOLECULAR DOCKING APPROACH WITH PROTEINS
Authors: Singh Krishna Pal , Dhasmana Anupam , Rahman Qamar
Published: March 2018

Objective: At present, toxicological tests are resource-intensive, time-consuming and require a large pool of animal models for toxicity assessment. To speed up the toxicity evaluation and to reduce animal suffering during toxicity assessment, the use of alternative methods including computational models is in high demand. The computational toxicity prediction methods are very helpful for the regulatory bodies to quickly assess the health impact of nanomaterial materials. In the present work, we have examined the mechanism of zinc oxide nanoparticle (ZnO-NP)-proteins interaction and their effect of surface chemistries of ZnO-NP on the bioactive conformation of chemokines and other cytological proteins using in silico molecular docking approaches.Methods: Molecular docking study was conducted using AutoDock 4.0 version and the visualization result using Discover Studio 4.0.Results: In the present study, we observed that ZnO-NP has high binding affinity with the mitogen-activated protein kinases (P-38), nuclear factor kappa-light-chain-enhancer of activated B cell (NF-kB) proteins, and matrix metallopeptidase-9 with docking energies −8.81, −7.64, and −7.27 Kcal/ Mol, respectively, involving with hydrogen, metal acceptor, and electrostatic interaction. The top interacting amino acid residues with ZnO-NP are GLY, PHE, ARG, ASP, GLN, and ASN.Conclusion: Thus, based on the molecular docking studies, we determine that the ZnO-NP is strongly interacting with the chemokines and other cytological proteins thus responsible for blocking of the activation stimuli for these proteins to initiate the biological signals for the proper functioning. The important interaction pattern ZnO-NP with the surface-enriched amino acid residues of chemokines and cytological proteins using molecular docking approach.
EFFECT OF FORMULATION FACTORS ON ORODISPERSIBLE TRIPTAN FORMULATIONS – NOVEL APPROACH IN TREATMENT OF MIGRAINE
Authors: Sirisha Yella , T E Gopala Krishna Murthy , Rao Avanapu Srinivasa
Published: March 2018

Objective: The present research work is an attempt to determine the effect of various diluents and superdisintegrants on drug release of eletriptan orodispersible tablets and designs an optimized formulation using 22 factorial design. Further, evaluate the tablets for various pre-compression and post-compression parameters.Methods: The drug excipient compatibility study was conducted by infrared spectroscopy, differential scanning colorimetry and X-ray diffraction studies were conducted to test the purity of the drug. The tablets were formulated by direct compression method using spray dried lactose, mannitol, microcrystalline cellulose, starch as diluents and crospovidone, croscarmellose sodium, and sodium starch glycolate as superdisintegrants. The powder formulations were evaluated for pre-compression parameters such as bulk density, tapped density, Carr’s Index, Hausner’s ratio, and angle of repose. The tablets were evaluated for post-compression parameters such as the hardness, thickness, friability, weight variation, and disintegrating time in the oral cavity, in vitro drug release kinetics studies, and accelerated stability studies. The formulations were optimized by 22 factorial design.Results: The drug and excipients were compatible, and no interaction was found. The drug was pure, and all the pre-compression parameters were within Indian Pharmacopoeial Limits. Post-compression parameters were also within limits. The disintegration time was found to be 27 s for the formulation F29 containing Croscarmellose sodium (5%) and Mannitol as diluent, and in vitro drug release was found to be 99.67% in 30 min and follows first-order kinetics. This was also the optimized formulation by 22 factorial design with a p=0.013.Conclusion: The orodispersible tablets of eletriptan were successfully formulated, and the optimized formulation was determined that can be used in the treatment of migraine.
DETERMINATION OF PHYSICOCHEMICAL PROPERTIES, ANTIOXIDANT CONSTITUENTS BY HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY FINGERPRINTING, AND ANTIOXIDANT ACTIVITY OF CUCURBITA MAXIMA SEEDS
Authors: Pal Pinki , Singh Shiv Bhadra , Singh Aaditya
Published: March 2018

Objective: The present study is designed to evaluate preliminary phytochemical constituents, physiochemical properties evaluation, free radical scavenging activity, and high-performance thin-layer chromatography (HPTLC) fingerprinting analysis of Cucurbita maxima seed oil.Methods: Total phenol content, total flavonoid content, total tannin content, 1, 1-diphenyl, 2-picryl-hydrazyl (DPPH) radical scavenging method, and HPTLC fingerprinting analysis for compounds responsible for antioxidant activity were used.Result: Phytochemical screening shows the presence of constituents such as alkaloids, glycosides, carbohydrates, fixed oil and fats, phytosterols, saponin, phenolic compounds, tannins, proteins, amino acids, gums, and mucilage. Physicochemical studies show that the oil contains an acid value, saponification value, iodine value of 9.53 mg KOH/g, 183 mg KOH/g, and 116.51 mg I2/100 g, respectively. Total phenol content was 3.9498±3.2 mg gallic acid equivalent/g, total flavonoid content was 56.115±4.6 mg rutin equivalent/g, and total tannin content was 19.4±0.40 mg tannic acid equivalent/g. The radical scavenging activity by DPPH Model shows that the methanolic extract has maximum antioxidant activity with IC50 value of 238.31. HPTLC fingerprinting also proofs the presence of phenol and flavonoid compounds in the seed oil.Conclusion: The results in the paper show that the C. maxima seed oil is an natural antioxidant and can be used for the treatment of various disorders.
DESIGN, FORMULATION AND EVALUATION OF LIPOSOME CONTAINING ISONIAZID
Authors: Roy Akshay Singha , Das Sudipta , Samanta Arnab
Published: March 2018

Objective: The objective of the present study was to formulate and evaluate liposomes loaded with isoniazid.Methods: Liposome of isoniazid was made by thin layer film hydration method. L-α-phosphatidylcholine and cholesterol were used to make multiamellar vesicles. Six batches of liposomes were prepared based on the different weight ratio of L-α-phosphatidylcholine and cholesterol. Differential scanning calorimetry (DSC) study conducted to study in any incompatibility.Results: The prepared liposomes were evaluated by particle size analysis, entrapment efficiency, release study and stability study. Particle sizes were determined from the scanning electron microscopy (SEM) photographs. When particle frequencies were plotted against particle diameter in the histogram, it showed that F1 batch had a skewed distribution towards smaller liposomes while F6 shows a proper bell-shaped curve with a mean at 225 mm. The percentage entrapment efficiency was found to be 8.99 ± 0.15 to 4.19 ± 0.12 % respectively. From the release profile, it was seen that F1 batch was fastest and F6 was slowest to release the drug. The satisfactory batch F1 was packed in Eppendorf tube and stored at 4 °C temperature for one month. At the end of one month, the samples were analyzed for their physical properties, drug entrapment and in vitro release profile. The percentage release was found to be 96.5 ± 3.2 after 4 h.Conclusion: The F1 batch showed most promising results compared to other. No significant change was found during one month’s stability study of final batch (F1).
SODIUM CROMOGLYCATE MUCOADHESIVE BUCCAL PATCHES: DESIGN, FABRICATION, IN VITRO AND IN VIVO CHARACTERIZATION
Authors: Sabry Shereen Ahmed
Published: March 2018

Objective: The purpose of this study was to design and formulate mucoadhesive buccal patches of sodium cromoglycate (SCG) as an alternative way to overcome its poor oral absorption and short half-life.Methods: Mucoadhesive patches were prepared by solvent casting technique using cellulose acetate butyrate (CAB) alone or in combination with mucoadhesive polymers like SCMC (sodium carboxymethyl cellulose), HPMC 100M (hydroxyl propyl methyl cellulose) and Cbp934P (carbopol) in different concentrations. The successful patches were evaluated for thickness, weight variation, folding endurance, tensile strength, drug content, surface pH, moisture uptake, swelling percentage, mucoadhesion strength, residence time, in vitro release study, ex vivo permeation and in vivo pharmacokinetic studies.Results: The thickness of all prepared patches ranged from 0.210±0.006 to0.355±0.012, folding endurance was more than 300, weight variation did not exceed 0.179±0.015, tensile strength and % elongation ranged from 6.4±0.018 to 13.1±0.024, and from 30.4±0.88 to 53.4±0.78respectively. The swelling percentage after one hour was from 20.8±0.99 to 53.2±1.5. pH of all prepared patches did not exceed 6.8, the drug content was about 99 to 101%, moisture uptake did not exceed 10%. Mucoadhesion strength and residence time ranged from 17.2±0.14 to 51.2±0.26, and from 3.35±0.25 to 7.45±0.28 respectively. The cumulative release percentage of SCG was in the following descending order CAB>CAB with Cbp934P>CAB with HPMC>CAB with SCMC. The optimized patch (F9) decreased the Cmax and increased Tmax compared to the parenteral solution.Conclusion: It can be concluded that mucoadhesive buccal patch is a promising dosage form to prolong the release of SCG and enhance its poor oral bioavailability.
A REVIEW ON OPTIMIZATION OF DRUG DELIVERY SYSTEM WITH EXPERIMENTAL DESIGNS
Authors: Khanam Nazia , Alam Md Irshad , Md Yusuf Ali Quazi Md Aamer Iqbal , Siddiqui Aquil-ur-rahman
Published: March 2018

The present review article aims at determining the various possible techniques available to enhance the quality, safety and efficacy of pharmaceutical formulations by exploring most suitable and practically applicable experimental designs and optimization techniques. As we know that pharmaceutical industries are constantly in search of novel ideas to improve quality by various optimization techniques, hence in present review article we shall discuss latest optimization techniques and experimental designs to achieve the best combination of product and process characteristics under the given set of conditions. Experimental designs and optimization techniques are the tools that are simultaneously and systematically used to identify various types of problems that may influence research, development and production of pharmaceutical formulations. These are organized an approach to determine the relationship between the factors affecting a process and the output of that process. The screening methods discussed here include factorial design, fractional factorial designs, full factorial design, mixture designs etc. Recently, different software has been used in implementing optimization techniques in pharmaceutical products to enhance product quality by using most suitable available facilities.
ANALYSIS OF MALE BOXER'S NICKNAMES
Authors: Omrčen Darija , Pečarić Hrvoje
Published: March 2018

Nicknaming of individual athletes and sports teams is a multifaceted phenomenon the analysis of which reveals numerous reasons for choosing a particular name or nickname. The practice of nicknaming has become so embedded in the concept of sport that it requires exceptional attention by those who create these labels. The goal of this research was to analyse the semantic structure of boxers’ nicknames, i.e. the possible principles of their formation. To realize the research aims 378 male boxers’ nicknames, predominantly in the English language, were collected. The nicknames were allocated to semantic categories according to the content area or areas they referred to. Counts and percentages were calculated for the nicknames in each subsample created with regard to the number of semantic categories used to create a boxer’s nickname and for the group of nicknames allocated to the miscellaneous group. Counts were calculated for all groups within each subsample.
CONTROVERSY IN THE CLASSROOM: THE CASE OF TRAINSPOTTING
Authors: Kalicanin Milena M.
Published: March 2018

Since learning a language naturally entails the understanding of a cultural context in which it is used (Kramsch, 1993), it goes without saying that cultural awareness will be best acquired when students immerse themselves in the country of the target culture (Istanto, 2008). The role of the teacher in nurturing cultural understanding is to “take on the role of culture educator and deliberately assist students with their process of cultural analysis.” (Istanto, 2009: 280) One of the ways to teach culture has definitely been to ask students to watch films of the target culture. This paper deals with the classroom experiment of teaching “Trainspotting”. The students were divided into two groups with the task of presenting and interpreting different aspects of the film for the sake of enhancing classroom communication, as well as introducing prevalent concerns of contemporary Scottish society.  The first (linguistic) group had to report on the usage of the authentic Scots in the film with a special attention to its title – to investigate the root and meaning of the word “trainspotting”, and the second (cultural) group had quite a demanding task to discuss the issues of urban Scottish youth culture. Though dealing with rather controversial themes, the practical case of teaching Trainspotting, based primarily on the interactive and communicative way of learning, verily illustrates “how film can be used in an innovative way for teaching the target language and culture” (Istanto, 2008:290).
FROM BOTH SIDES OF THE CLASSROOM: PERSPECTIVES ON TEACHER FEEDBACK ON ACADEMIC WRITING AND FEEDBACK PRACTICE
Authors: Leong Alvin Ping , Lee Hwee Hoon
Published: March 2018

Research on feedback on student writing has investigated numerous aspects over the years. However, focused studies involving perspectives of both teachers and students in a particular educational setting are rare. This study investigated the views of teachers and students from a university in Singapore regarding feedback on academic writing and feedback practice. Nine experienced writing teachers and eight undergraduates participated in focus-group discussions in separate sessions. Discussions covered topics on the purpose of feedback and the specific areas that feedback should cover. Both teachers and students agreed that the purpose of feedback should be to help students become reflective and independent learners. The teachers tended to use feedback to justify the grades awarded to the assignments, and tailored their feedback to the requirements of the respective courses. The students, however, felt that the feedback needed to be more detailed. The individual needs of the students were also not always met. We propose recommendations to create a dialogic environment between teachers and students, and so facilitate the provision of personalized feedback on academic writing.
Delimitación y determinación del margen exterior de la plataforma continental más allá de las 200 M. Dos procesos distintos
Authors: Lamas Ovando Ana Paula
Published: March 2018

La Convemar sienta las bases sobre las cuales los Estados costeros podrán trazar y delimitar los márgenes de la plataforma continental más allá de las 200 M. Los Estados costeros deben trazar los márgenes de su plataforma continental con base en las recomendaciones que emita la CLPC; dichos márgenes serán definitivos y obligatorios. No obstante, al analizar la extensión de los márgenes, se pueden encontrar traslapes de la plataforma continental entre Estados con costas situadas frente a frente o adyacentes; en tales casos, los Estados deben delimitar. Es en relación con estos traslapes donde se observa la importancia e independencia de ambos procesos, así como la posible prevalencia del proceso de delimitación sobre el de determinación de los límites de la plataforma continental.
Las declaraciones de los Estados y la Convención de las Naciones Unidas sobre el Derecho del Mar de 1982. Su aplicación al sistema de solución de controversias en el asunto del Mar del Sur de China (Filipinas v. China)
Authors: Godio Leopoldo M. A.
Published: March 2018

El presente trabajo analiza el uso de las declaraciones interpretativas y sus actuales desafíos, con especial énfasis en la situación que presentan los artículos 287, 298, 309 y 310 de la Convención de las Naciones Unidas sobre el Derecho del Mar de 1982 a la luz del caso reciente y no por ello menos polémico: la controversia entre Filipinas y China en el área del Mar del Sur de China.
Dampak Transmigrasi Terhadap Kehidupan Sosial Masyarakat: Studi Sejarah Masyarakat Timpeh Dharmasraya
Authors: Nova Yosi
Published: March 2018

Dharmasraya regency is once the destination of transmigration for Suamtera region. Some of them is Timpeh. The pattern of transmigration in Timpeh is general transmigration and local transmigration. Dharmasraya is of the most successful transmigration destination in Indonesia withTransmigration Award “Makarti Nayomata from the Indonesian minister of Transmigration in 2012 as indicator. This study conducted with qualitative research. Data collected through document study, interviews and observation. Result is the Dharmasraya transmigration program succesfull aired on nation TV station once year after. Transmigration program bring the changes on the social life of Timpeh. Transmigration conducted the new social identity, new culture and the pattern of economic development in Timpeh.  Kabupaten Dharmasraya adalah salah satu daerah tujuan transmigrasi untuk wilayah Sumatera. Di antara beberapa daerah yang berada dalam Kabupaten Dharmasraya yang menjadi daerah tujuan transmigrasi adalah Timpeh. Pola transmigrasi yang berlangsung di kecamatan Timpeh adalah Transmigrasi Umum (TU) dan Transmigrasi Lokal. Dalam menjalankan program transmigrasi yang diadakan oleh pemerintah, kabupaten Dharmasraya adalah contoh daerah tujuan transmigrasi yang paling berhasil di Indonesia, hal ini dibuktikan dengan penghargaan Transmigration Award “Makarti Nayomata” dari Mentri Tenaga Kerja dan Transmigrasi Republik Indonesia yang diraih oleh kabupaten Dharmasraya pada tahun 2012. Atas prestasi ini, maka tahun selanjutnya keberhasilan program transmigrasi di Kabupaten Dharmasraya juga ditayangkan di stasiun televisi nasional. Penelitian dilakukan secara qualitatif di nagari kecamatan Timpeh. Data dikumpulkan melalui studi dokumen, wawancara dan observasi. Hasil penelitian menunjukkan bahwa Program transmigrasi ternyata telah membawa banyak perubahan dalam berbagai bidang kehidupan masyarakat kecamatan Timpeh. Transmigrasi membentuk identitas baru sosial, budaya masyarakat serta pola pembangunan ekonomi.
THE ROLE OF NAA, GA3, ACTIVATED CHARCOAL, AND SUCROSE ON ZYGOTIC EMBRYOS CULTURE OF HYBRID OG OPEN POLLINATED CLONE (Elaeis guineensis JACQ. X Elaeis oleifera)
Authors: Ernayunita Ernayunita , Rahmadi Hernawan Yuli , Harahap Iman Yani , Purba Abdul Razak
Published: March 2018

Oil palm OG hybrid genetic potentials are high in term of vegetative and generative traits, such as: low height increment, compact palm, high free fatty acid and high carotenes. However, OG hybrid reproduction is hindered due to its low germination rate. So, alternative method for germination is needed, which is in vitro embryo zygotic culture. This study objective was to reveal the best medium composition for OG hybrid embryo culture by modificated several oil palm basic medium from oil palm tissue culture protocol and to understand the role of plant growth regulators, activated charcoal, and sucrose on in vitro growth and development of OG hybrid embryo. The design used was Completely Randomized Design (CRD) with 16 replication and 4 embryos for each replicates, while the treatments were: A1 = M129 (control); A2 = M129 + activated charcoal; A3 = M129+ activated charcoal + sucrose; A4 = ½ M129 + activated charcoal + sucrose; A5 = M129 + GA3 ; and A6 = M129 + GA3 + NAA. From the study we found that the best medium for OG hybrid open pollinated clone's embryo culture was M129 with GA3 and NAA (A6). This medium gave percentage of in vitro germination up to 14.06%, and later on the plantlets from this medium gave the best vegetative growth performance such as high number of leaves and primer roots.
WORLDVIEW-2 IMAGERY VEGETATION INDEX CALCULATION FOR OIL PALM YIELD ESTIMATION
Authors: Wilansyah Afdi , Wiratmoko Dhimas , Hartono Hartono , Murti BS Sigit Heru
Published: March 2018

Remote sensing application that used integrated with environmentally factors for oil palm yield estimating using Worldview-2 Imagery vegetation index (VI) was done. The aims of this study to get : 1) Red Edge Normalized Different Vegetation Index (RENDVI) and C h l o r o p h y l l I n d e x R e d E d g e ( C IRE ) ; 2) Correlation both of VI and oil palm yield; 3) oil palm yield estimation. The methods that used in this study were VI calculation by using RENDVI [(λNIR -λRED EDGE)/(λNIR +λRED EDGE )] and CIRE = [(λNIR /λRED EDGE )-1]. Oil EDGE NIR RED EDGE NIR RED EDGE palm yield estimation done by using linier regression and multiple linier regression. Linier regression used oil palm yield as dependent factor (Y) and VI as independent factor. Multiple linier regression used oil palm yield as dependent factor (Y), vegetative factors (oil palm yield, population per hectars, leaf area index) and environmentally factor (% clay, soil fertility index, altitude and water balance) as independent factors. The results of this study were: 1) the RENDVI value range -1 to 0.493 with average 0.30; while the CIRE value range -1 until 1.845 with average value 0.85. 2) The RENDVI dan CIRE have low positive linier correlation with oil pal yield rendah (rRENDVI = 0.355 dan rCIRE = 0.354); 3) Oil palm RENDVI CIRE yield estimation that using RENDVI and CIRE , vegetatation factors, environmentally factors data integration have similar correlation (r=0.763). Overall estimation model accuration get more than 90% estimation accuration on current month.
DESAIN PERANCANGAN DAN IMPLEMENTASI STRATEGI PENJUALAN BERBASIS E- COMMERCE PADA TOKO SLAYA BAN SERANG
Authors: Muttaqin Zaenal , Fredricka Jhoanne , Andayani Andayani
Published: March 2018

%Slaya Ban merupakan salah satu toko yang bergerak di bidang otomotif. %Slaya Ban menyediakan penjualan produk-produk otomotif dan jasa modifikasi. Saat ini dalam penjualannya %Slaya Ban masih menggunakan metode konvensional dan pelanggan yang datang hasil dari informasi mulut ke mulut. Maka dibuatlah perancangan strategi informasi untuk penyebaran informasi penjualan dan jasa modifikasi dalam bentuk e-Commerce. Metode yang digunakan adalah analisis dan perancangan strategi e-Commerce, dimana pada tahap analisis, akan di analisis kesempatan pangsa pasarnya, hambatan dan tantangannya. Kemudian dilanjutkan tahap perancangan dan akan membahas mengenai user interface, komunikasi pasar dan membangun sebuah brand,implementasi dan metriks. Dengan menggunakan sistem informasi strategi e-Commerce diharapkan dapat meningkat kan penjualan dan penyebaran informasi di masyarakat mengenai produk dan jasa yang disediakan oleh %Slaya Ban. VirtueMart merupakan salah satu aplikasi extention yang berfungsi untuk mendesain sistem pembayaran pada e-Commerce.
SISTEM INFORMASI GEOGRAFIS PEMETAAN PRAKTIK DOKTER UMUM DAN SPESIALIS “SMART DOCTOR”
Authors: Maulana Muhammad Akbar , Kriswantoro Andi , Hudha Yans Safarid , Habib Muhammad , Syarham Syarham , Utami Ema
Published: March 2018

Ketika seseorang sedang sakit dan baru saja pindah kedaerah tertentu, akan sulit dalam mencari dokter pada kota yang baru saja didatangi dan sangatlah menyusahkan. Terlebih lagi jika banyak dokter yang tidak kita kenal dan belum teruji bahwa dokter tersebut mempunyai izin praktek. Tentunya harus pergi ke rumah sakit, tetapi jika lebih mengetahui dimana letak dokter yang terdekat dan terpercaya, ini akan menghemat tenaga dan waktu. Dengan membuat smart doctor diyakini dapat mensolusikan masalah yang dihadapi masyarakat. Perkembangan komunikasi dalam modernisasi saat ini khususnya di Indonesia semakin berkembang pesat, fakta ini dapat dibuktikan dengan berkembangnya berbagai jenis smartphones yang dibuat vendor-vendor ponsel terkemuka didunia. Hal ini baik secara langsung maupun tidak langsung berpengaruh terhadap perkembangan dunia kesehatan di Indonesia dalam mengembangkan berbagai macam teknologi. Ketersediaan perangkat bergerak, lingkungan pengembangan, dan pustaka pemetaan, memungkinkan berkembangnya aplikasi mobile GIS yang berhubungan dengan dunia kesehatan. Dalam pengembangan aplikasi ini menggunakan sistem operasi android yang merupakan salah satu sistem operasi telepon seluler yang terpopuler saat ini dipadukan dengan google maps yang merupakan layanan peta dunia virtual berbasis web yang disediakan oleh Google. Pemanfaatan pengukuran jarak terdekat pada peta juga memberikan keuntungan lebih pada aplikasi ini dimana nantinya pengguna yang tidak mengetahui rute jarak menuju lokasi praktik dokter dapat dipermudah dengan di arahkan menggunakan rute terpendek sehingga hal itu dapat membatu bagi pengguna yang bukan merupakan penduduk asli dari suatu wilayah tersebut.
The Design Of ERP Connected Inside University To Face Globalization
Authors: Gamayanto Indra , Efrilianda Devi ajeng efrilianda , Utomo WM Ibnu
Published: March 2018

Dampak perkembangan teknologi informasi demikian besar terhadap berbagai bidang kehidupan, terutama di dunia pendidikan, salah satunya Universitas. Universitas diharapkan tidak hanya menghasilkan penelitian yang hanya berbasis pada teori, tetapi penerapakan dan menghasilkan keuntungan kepada masyarakat, Negara, Kopertis dan DIKTI. Dalam jurnal ini, beberapa jurnal digunakan sebagai dasar dalam pengembangan ERP Education Connected: Journal- The impact of emotionality and self-disclosure on online dating versus traditional dating dan Lunenburg,F.C (international journal of scholarly, academic, intellectual diversity. Hasil dari ERP Education connected adalah menyatukan semua sistem sehingga menjadi terintegrasi antar Unviversitas dan company sehingga penelitian yang dihasilkan dapat memberikan dampak besar dan juga dapat dihasilkan banyak hak paten/cipta sehingga masyarakat dan Negara memperoleh hasil maksimal dari universitas. Lebih jauh lagi, penyatuan sistem ini juga akan dapat menghasilkan terkumpulnya informasi dengan lebih mendetails sehingga para peneliti dapat mengembangkan penelitiannya dengan lebih mudah. Hasil yang akan diperoleh dari jurnal ini adalah bahwa data yang akurat akan dapat menghasilkan ketepatan penelitian yang menghasilkan keuntungan kepada pihak universitas dan pemerintah.
The virgin of Savina identity and multiculturalism
Authors: Matic Marina
Published: March 2018

The sixteenth-century miracle-working icon of the Virgin Glykophilousa in the
Serbian Orthodox monastery of Savina, modern Montenegro, has been the focus
of cult and devotions for centuries. A compelling visual presence, it played
multiple roles: liturgical, social, legal, and cultic. In each of its
roles, it provided support for ethnic and religious identity, being above
all a palladium both for believers as individuals and for the Orthodox
Christian community as a whole in the complex multicultural and
multiconfessional contexts of foreign Venetian rule in the
eighteenth-century Gulf of Kotor (Boka Kotorska/Bocche di Cattaro).
On parliamentary democracy in Serbia 1903-1914 political parties, elections, political freedoms
Authors: Batakovic Dusan
Published: March 2018

Parliamentary democracy in Serbia in the period between the May Coup of 1903
and the beginning of the First World War in 1914 was, as compellingly shown
by the regular and very detailed reports of the diplomatic representatives of
two exemplary democracies, Great Britain and France, functional and fully
accommodated to the requirements of democratic governance. Some shortcomings,
which were reflected in the influence of extra-constitutional
(?irresponsible?) factors, such as the group of conspirators from 1903 or
their younger wing from 1911 (the organisation Unification or Death),
occasionally made Serbian democracy fragile but it nonetheless remained
functional at all levels of government. A comparison with crises such as
those taking place in, for example, France clearly shows that Serbia,
although perceived as ?a rural democracy? and ?the poor man?s paradise?, was
a constitutional and democratic state, and that it was precisely its
political freedoms and liberation aspirations that made it a focal point for
the rallying of South-Slavic peoples on the eve of the Great War. Had there
been no firm constitutional boundaries of the parliamentary monarchy and the
democratic system, Serbia would have hardly been able to cope with a series
of political and economic challenges which followed one another after 1903:
the Tariff War 1906-11; the annexation of Bosnia-Herzegovina 1908/9; the
Balkan Wars 1912-13; the crisis in the summer of 1914 caused by the so-called
Order of Precedence Decree, i.e. by the underlying conflict between civilian
and military authorities. The Periclean age of Serbia, aired with full
political freedoms and sustained cultural and scientific progress is one of
the most important periods in the history of modern Serbian democracy.
Contacts between Duklja/Zeta and the Apennine Peninsula in the middle ages as a topic in Montenegrin periodicals in 1835-1941
Authors: Jovovic Vasilj
Published: March 2018

This paper shows that continuity of connections between Duklja/Zeta and the
Apennine Peninsula during the middle ages, which were manifested both in the
political and in the cultural sphere, attracted attention as a topic in the
periodical press issued in the territory of present-day Montenegro from 1835
to 1941. The paper offers a systematized overview of such, for the most part
descriptive, texts on political and cultural links between what now are
Montenegro and Italy in the middle ages.
Creating a communist Yugoslavia in the Second World War
Authors: Nikolic Kosta , Dobrivojevic Ivana
Published: March 2018

The Second World War involved the conflict of three different ideologies -
democracy, fascism and communism - an aspect in which it was different from
the Great War. This ideological triangle led to various shifts in the
positions, views, and alliances of each of the warring parties. Yugoslavia
with its historical legacy could not avoid being torn by similar ideological
conflicts. During the Second World War a brutal and exceptionally complex war
was fought on its soil. The most important question studied in this paper
concerns the foremost objective of the Communist Party of Yugoslavia (KPJ) -
to carry out a violent change of the legal order and form of government of
the pre-war Kingdom of Yugoslavia.
Elena Ceauşescu’s personality cult and Romanian television
Authors: Sorescu-Marinkovic Annemarie
Published: March 2018

Elena Ceau?escu, spouse of the Romanian communist leader Nicolae Ceau?escu,
generated in the 1980s a gigantic homage industry, as she was the object of a
personality cult as strong as that of her husband?s. This paper briefly
outlines the origin and elements of Nicolae Ceau?escu?s personality cult, to
focus then on Elena Ceau?escu?s cult: how at first it was merged with the
cult of her husband, her being a mere companion of the head of state, and
then grew to the point of paralleling that of Nicolae Ceau?escu during the
last years of communist rule in Romania. The second part focuses on the
evolution of Romanian state television and its crucial role in the diffusion
of her personality cult, showing how this state institution became completely
subordinated to the presidential couple in the 1980s, and pointing to a
paradox of the period: the shorter Romanian television?s daily broadcasting
time, the larger the amount of programming on Ceau?escu. Finally, the paper
shows how January was infused with anniversary dates meant to consolidate the
personality cult of the presidential couple and to reinvent communist
traditions.
Fiction concept by Hans Vaihinger
Authors: Radinkovic Zeljko
Published: March 2018

This text primarily deals with Hans Vaihinger?s fiction theory. Emphasizing
the central role of scientific fiction in that theory, it attempts to give a
critical account of Vaihinger?s philosophical theory of ?As if?. On the one
hand, this analysis of the philosophy of ?As if? includes conceptual
delimitation between the notion of fiction and concepts of fantasy,
hypothesis, and regulatory ideas. On the other hand, it points out to some
problems related to Vaihinger?s constructivist-pragmatic approach to the
problem of fiction, such as a tendency towards an unreasonable extension of
the notion of fiction, and a tendency towards the integration of other forms
of fictionality into scientific fiction.
Qualidade de vida do idoso e a existência de netos: estudo comparativo no distrito de Lisboa
Authors: Ferreira Inês , Duque Eduardo
Published: March 2018

“Ser avô” é um acontecimento marcante, apesar de ser cada vez mais raro. Os netos são uma fonte de estimulação para os avós, contribuindo para a luta contra o declínio do envelhecimento e proporcionando-lhes uma melhor qualidade de vida. Os resultados evidenciam que as relações sociais são importantes para o idoso poder usufruir de qualidade de vida, mas será que os netos fazem a diferença quando falamos da qualidade de vida dos avós?  Palavras-chave: Qualidade de vida; Avós; Netos; Idosos.
IMPLEMENTASI UNDANG-UNDANG PERDAGANGAN DAN IMPLIKASINYA DALAM PENGENDALIAN HARGA KEBUTUHAN POKOK MASYARAKAT
Authors: Engkus Engkus
Published: March 2018

Dengan diterbitkannya Undang-Undang Nomor 7 Tahun 2014 Tentang Perdagangan, Indonesia mempunyai harapan baru untuk menata carut marutnya perdagangan kebutuhan pokok masyarakat (Kepokmas) yang berlangsung bertahun-tahun selama ini. Masalah utama dalam penelitian ini bahwa “kenaikan dan penurunan harga secara fluktuatif” yang terjadi berulang-ulang di setiap bulan Ramadhan. Hal ini disebabkan oleh beberapa faktor diantaranya ketidakseimbangan permintaan dan penawaran (supply and demand) yang belum dikelola secara optimal. Tujuan penelitian ini mengumpulkan data, fakta dan menganalisis masalah-masalah, serta secara langsung dan tidak langsungingin mengetahui dan menambah nuansa akademik secara teori, juga ingin mengetahui secara mendalam tentang tata kelola tersebut. Penelitian ini merupakan penelitian kualitatif dengan mengunakan teknik observasi, interview, historik dokumental dan teknikdokumental audio visual. Hasil penelitian, sebelum, saat dan setelah bulan ramadhan perkembangan harga masih naik dan fluktuatif. Intervensi pemerintah dengan kebijakanprogram jangka pendeknya tidak menyentuh secara berkelanjutan, sehingga kejadian: penimbunan belum ada ketegasan Aparat Penegak Hukum (APH), kelangkaan, tidak tercukupinya pasokan, permintaan meningkat, akibat konsumsi masyarakat bertambah, yang pada akhirnya menimbulkan harga yang membumbung tinggi. Kesimpulan:Kebijakan pengendalian harga kepokmas, perlu dilengkapi dengan meredesainkebijakan yang komprehensif, terintegrasi, partisipatif, dan keberlanjutanmulai dari pemerintahan pusat sampai ke daerah, menuju kemandirian bangsa dalam pangan.

Kata kunci: Kenaikan Harga, Ketegasan Aparat, Pengendalian.
ENFORCEMENT PATTERN OF CRIMINAL LAW BASED ON HUMANITY VALUES IN THE UTILITY PRINCIPAL PERSPECTIVE
Authors: Batubara Gialdah Tapiansari , Susanto Anthon Freddy
Published: March 2018

[Enforcement Pattern Of Criminal Law Based On Humanity Values In The Utility Principal Perspective] The current Criminal Code is laden with weaknesses, so it is urgent to be replaced by a law-oriented Criminal Code that is closer to the characteristics of the Muslim law (Custom and Law Family), which features Indonesian characteristics (moving from the collective and personal order, reflecting the nation's political ideology ) of Pancasila. One of the selected Pancasila values ​​is humanitarian value. Human values ​​are values ​​that show respect for human beings, because they are essentially legal to human beings. In the realm of material criminal law, human values ​​are reflected in the principle of individualization of punishment (the principle of individuality, flexibility, modification, forgiveness, and culpability), as seen in the National Criminal Code Bill. Not accommodating humanitarian values ​​in the formulation stage will be fatal at the law enforcement stage, but it is also fatal if the error in the formulation stage is left at law enforcement stage, so it is necessary to nationalize the pattern of criminal law enforcement one of them based on humanitarian value, less focus on punishment, contain prevention strategies, strategies for imposition of prison criminal sanctions are ultimum remedium, benefit strategy and balance of interest protection and restoration of relations between perpetrators, victims, community and state, social defense strategy with a rational policy approach that includes the use of economic approach , productive action strategies and contribute to national development in order to realize the legal objectives of benefits.

Keywords: Value, Humanity, Pancasila, Enforcement, Benefit.
KEPASTIAN HUKUM PENILAIAN KEBARUAN DESAIN INDUSTRI DI INDONESIA BERDASARKAN PENDEKATAN KEKAYAAN INTELEKTUAL DAN PERBANDINGAN HUKUM
Authors: Mayana Ranti Fauza
Published: March 2018

Perlindungan Desain Industri, seperti halnya kekayaan intelektual didasarkan pada kemampuan kreativitas manusia melalui cipta, rasa dan karsa. Menurut Pasal 25 ayat (1) TRIPs Agreement Desain Industri yang dilindungi adalah Desain Industri yang baru atau orisinal, ketentuan ini menganut asas bahwa kebaruan suatu desain diperoleh ketika desain significantly differ dari yang sebelumnya, kebaruan disini mencakup newness / novelty  dan originality, artinya kebaruan merupakan dasar utama pemberian hak Desain Industri, sedangkan asas ini tidak sepenuhnya diadopsi dalam ketentuan Desain Industri. Ketentuan Desain Industri di Indonesia hanya mensyaratkan kebaruan tanpa memberikan kejelasan mengenai bagaimana menginterpretasikan syarat kebaruan sehingga banyak sekali Hak Desain Industri yang diperoleh berdasarkan pendekatan Minor Change dimana sedikit saja perbedaan pada bentuk dan konfigurasi pada dasarnya telah menunjukkan adanya kebaruan. Pendekatan minor change dianggap mengesampingkan aspek orisinalitas dan kurang dapat memberikan kepastian hukum pemegang Hak Desain Industri terdaftar. Tulisan ini bertujuan menggali pendekatan minor change sebagai dasar penilaian kebaruan Desain Industri dalam perspektif perbandingan hukum dibeberapa negara dunia yaitu Amerika Serikat, Jepang, Uni Eropa dan Australia sebagai bahan kajian dan referensi dalam upaya pembentukan perlindungan Hak Desain Industri di Indonesia yang dapat memberikan kepastian hukum.

Kata Kunci: Kebaruan Desain Industri, Perbandingan Hukum.
Kanta-arkiston käyttökokemuksia työterveyshuollossa
Authors: Nissinen Sari Päivikki , Soini Satu , Leino Timo , Hakulinen Hanna , Saranto Kaija
Published: March 2018

Sosiaali- ja terveysministeriön laatiman Sote-tieto hyötykäyttöön -strategian tarkoituksena on mahdollistaa, että terveydenhuollon ammattilaisella on käytössään ajantasainen potilastieto ja työtä tukevat tietojärjestelmät. Tietojen vaihto yli organisaatiorajojen toteutetaan valtakunnallisen Potilastiedon arkiston (Kanta-arkiston) avulla. Arkistoon on tallennettu tietoja lähes kaikista suomalaisista ja sen käyttö lisääntyy terveydenhuollon ammattilaisten keskuudessa koko ajan.

Tutkimuksen tarkoituksena oli selvittää Kanta-arkiston käyttöä työterveyshuollossa. Sähköinen kysely lähetettiin työterveyslääkäreille, työterveyshoitajille, työfysioterapeuteille ja työterveyspsykologeille kesällä 2017 ja siihen vastasi yhteensä 359 henkilöä.

Tulokset osoittavat, että Kanta-arkistoa pidetään hyvänä ideana, mutta sitä käytetään vielä vähän. Vastaajat kokevat, että tietojen haku on hidasta, tarvittavan tiedon löytäminen hankalaa ja potilastietojen tallentumisessa Kanta-arkistoon on ajoittain viivettä. Lisäksi Kanta-arkistossa näkyvät potilaskäyntien päivämäärät eivät aina välttämättä vastaa käynnin todellista ajankohtaa. Työterveyshuollon ammattilaiset uskovat muiden ammattilaisten hyödyntävän työterveyshuollossa syntyneitä tietoja, vaikka kokevatkin, että Kanta-arkiston avulla kokonaiskuvan saaminen potilaan hoidon tilanteesta ei onnistu helposti.

Tietojen ajantasainen kirjaaminen ja niiden tallentuminen Kanta-arkistoon mahdollistaa potilaalle parhaan mahdollisen hoidon, kun ammattilaiset saavat tarvittaessa esille potilaan koko terveys- ja sairaushistorian. Vaikka Kanta-arkiston käyttö on vielä osin hankalaa ja tietojen löytämisessä on vaikeutta, voidaan kuitenkin sanoa sen täyttävän tarkoituksensa ja hyödyttävän työterveyshuollon ammattilaisen työtä. Tulevaisuudessa tilanne tulee paranemaan, kun Kanta-arkistoon toteutettavan tiedonhallintapalvelun kautta saadaan ammattilaisille käyttöön kooste potilasta koskevista keskeisistä terveystiedoista.
Common controls driven conceptual leadership framework
Authors: Mussalo Petteri , Hotti Virpi , Kirjanen Anastasia , Lauronen Henna , Holopainen Jukka , Härkönen Hannu , Huikari Juho
Published: March 2018

The forthcoming social welfare and healthcare reform in Finland with its organizational, financing and steering changes challenges the leadership. All service systems levels of the social welfare and healthcare have to achieve performance objectives whilst at the same time also meeting conformance requirements. However, there are hundreds authority documents (e.g., best practices, guidelines, regulations and standards) the common controls of which are adapted partly manually and partly by leveraging automation in organizations. Leaders review and develop their practices around performance and conformity (i.e., conformance or compliance) within frameworks that are mainly the sets of principles. However, the common controls affect into the main tasks of the governance (i.e., direct, evaluate and monitor). Therefore, we construct a conceptual leadership framework to highlight the meaning of the common controls and the meaning of criteria for performance and conformity. The constructed framework contains the terms (e.g., a control objective, decision criteria, event, insight, and transaction) that are mainly defined in the glossaries of the authority documents. The terms are used to find out terms and definitions for the leadership framework to figure out cognitive meanings for the concepts of the common controls driven leadership.
MES « RENCONTRES » AVEC HÉLÈNE DORION. LECTURES POLYGONALES ET HERMÉNEUTIQUES
Authors: MALITA Ramona
Published: March 2018

My literary « encounters » with Hélène Dorion. Polygonal and hermeneutic readings. Our article is a hermeneutic analysis on Hélène Dorion’s poem in prose, « The knowledge of the wave » in volume New Beginnings published in 2014. According to hermeneutical model proposed by Paul Ricoeur, we shall analyze four levels of reading: literal, tropological/symbolic, typological and ontological reading. We will also try to expose the intertextuality of this poem, that means which are the texts in dialogue: the parable of the ten vigrins and the biblical episode of Noah. We then propose a dialogue with the visual arts: Victor Hugo’s engraving, The wave-My destiny. In turning to study the connection between the poem and the image, Hélène Dorion’s poetry and Victor Hugo’s engraving at the time of his exile, we shall be analyzing the philosophical influences.
REZUMAT. « Întâlnirile » mele cu Hélène Dorion. Lecturi poligonale și hermeneutice. Articolul propune o analiză hermeneutică a poemului în proză al scriitoarei canadiene Hélène Dorion « La Connaissance de la vague », din volumul Recommencements, apărut în 2014. După modelul propus de Paul Ricoeur, analiza se construiește în patru niveluri de lectură: literală, tropologică/simbolică, tipologică și ontologică. Textele biblice ale parabolei fecioarelor înțelepte și ale corabiei lui Noe par să intre, după părerea noastră, în dialog (intertextual) cu acest poem; am detaliat aceste posibile similitudini alături de convergențe cu arta vizuală: desenul lui Victor Hugo, Valul (ce datează din perioada exilului scriitorului francez). 
Cuvinte-cheie: Hélène Dorion, volumul Recommencements, poem narativ, literatură canadiană, parabolă, analiză hermeneutică.