bluuebunny/crossref_metadata_2025 huggingface dataset:
Aerobic Exercise in HIV-Associated Neurocognitive Disorders: Protocol for a Randomized Controlled Trial
Authors: Nweke Martins , Mshunqane Nombeko , Govender Nalini , Akinpelu Aderonke , Ogunniyi Adesola
Published: January 2022

Background

Since the introduction of antiretroviral therapy (ART), the incidence of HIV-associated dementia has drastically fallen. Despite using ART, people living with HIV continue to experience less severe but limiting forms of HIV-associated neurocognitive disorder (HAND). People living with HIV who are on ART and experiencing symptoms of HAND may benefit from aerobic exercise.

Objective

This protocol describes a randomized controlled trial designed to determine the effects of a 12-week aerobic exercise program on HAND in Southeastern Nigeria.

Methods

At least 68 patients diagnosed with HAND will be randomly placed into either an aerobic exercise group or control group. Patients in the aerobic exercise group will perform a moderate intensity workout on a stationary bicycle ergometer, 3 times a week for 12 weeks. We will measure the primary outcomes including neurocognitive performance, prevalence of HAND, viral load, and CD4 count. We will evaluate postexercise neurocognitive performance using reliable neuropsychological tests relevant to people living with HIV, in line with the Frascati criteria. We will assess secondary outcomes such as quality of life, activity limitation, and social participation using the World Health Organization Quality of Life (WHOQOL)-Brief, and the Oxford Participation and Activities questionnaire. We will use exploratory statistics to test the data for normality and homogeneity. We will analyze the effect of the exercise program on HAND using relative risk (RR) and absolute risk reduction (number needed to treat). Analysis of covariance will be run to estimate the effect of exercise on quality of life and activity and participation level.

Results

This funded trial was approved by the Institutional Review Board in May 2020. The protocol was approved on June 15, 2020. Enrollment commenced in January 2021 and was completed in May 2021. Over 60% of the participants were recruited at the time of first submission to JMIR Mental Health. Data curation is still ongoing; hence, data analysis is yet to be executed. Study outcomes are expected to be published in March 2022.

Conclusions

This is a protocol for a randomized controlled trial that aims to evaluate the effect of a 12-week aerobic exercise program on HAND in Southeastern Nigeria.

Trial Registration

Pan African Clinical Trials Registry PACTR202009483415745; https://tinyurl.com/2p97zpu9

International Registered Report Identifier (IRRID)

PRR1-10.2196/29230
Machine Learning Support for Decision-Making in Kidney Transplantation: Step-by-step Development of a Technological Solution
Authors: Paquette François-Xavier , Ghassemi Amir , Bukhtiyarova Olga , Cisse Moustapha , Gagnon Natanael , Della Vecchia Alexia , Rabearivelo Hobivola A , Loudiyi Youssef
Published: January 2022

Background

Kidney transplantation is the preferred treatment option for patients with end-stage renal disease. To maximize patient and graft survival, the allocation of donor organs to potential recipients requires careful consideration.

Objective

This study aimed to develop an innovative technological solution to enable better prediction of kidney transplant survival for each potential donor-recipient pair.

Methods

We used deidentified data on past organ donors, recipients, and transplant outcomes in the United States from the Scientific Registry of Transplant Recipients. To predict transplant outcomes for potential donor-recipient pairs, we used several survival analysis models, including regression analysis (Cox proportional hazards), random survival forests, and several artificial neural networks (DeepSurv, DeepHit, and recurrent neural network [RNN]). We evaluated the performance of each model in terms of its ability to predict the probability of graft survival after kidney transplantation from deceased donors. Three metrics were used: the C-index, integrated Brier score, and integrated calibration index, along with calibration plots.

Results

On the basis of the C-index metrics, the neural network–based models (DeepSurv, DeepHit, and RNN) had better discriminative ability than the Cox model and random survival forest model (0.650, 0.661, and 0.659 vs 0.646 and 0.644, respectively). The proposed RNN model offered a compromise between the good discriminative ability and calibration and was implemented in a technological solution of technology readiness level 4.

Conclusions

Our technological solution based on the RNN model can effectively predict kidney transplant survival and provide support for medical professionals and candidate recipients in determining the most optimal donor-recipient pair.
The French version of the Electronic Health Literacy Scale (eHEALS): translation and validation study (Preprint)
Authors: Chaniaud Noémie , Sagnier Camille , Loup-Escande Emilie
Published: January 2022

BACKGROUND

E-health literacy is emerging as a crucial concept for promoting patient self-management in an overloaded hospital system. However, to our knowledge, no tool currently exists to measure the level of e-health literacy of French-speaking people.

OBJECTIVE

We propose a translation in French of the eHealth Literacy Scale (eHEALS) and a validation of this French version (F-eHEALS).

METHODS

The validation of the F-eHEALS scale followed the 5 steps of the transcultural validation method: (1) a double reverse translation, (2) a validation by a committee of experts (n = 4), (3) a pre-test in order to check the clarity of the items (n = 22), (4) the administration of the scale in French via an online quantitative study combined with two other questionnaires (HLS-EU-16, PAM-13) (n = 328), and finally (5) a test-retest (n = 78) in order to check the temporal stability of the measurements obtained from the scale.

RESULTS

The results obtained for the measurement of factor structure, internal consistency and temporal stability prove the validity and fidelity of the proposed scale. The factor analysis with Varimax Rotation used to validate the construct showed a two-factor scale. The effect of the construct was analysed using three hypotheses related to the theory. The F-eHEALS score was correlated with the HLS-EU-Q16 score (r = 0.34, P < .001) and the PAM-13 score (r = 0.31, P < .001).

CONCLUSIONS

The French version of the e-HEALS is in line with the original version. It presents adequate levels of validity and fidelity.
Participants’ Perceptions of Essential Coaching for Every Mother—a Canadian Text Message–Based Postpartum Program: Process Evaluation of a Randomized Controlled Trial (Preprint)
Authors: Dol Justine , Aston Megan , McMillan Douglas , Tomblin Murphy Gail , Campbell-Yeo Marsha
Published: January 2022

BACKGROUND

“Essential Coaching for Every Mother” is a Canadian text message–based program that sends daily messages to mothers for 6 weeks after they give birth. There is a need to explore the program’s effectiveness in terms of the participants’ experience to guide refinement and modification.

OBJECTIVE

This study aimed to describe the process evaluation of the Essential Coaching for Every Mother randomized controlled trial through an evaluation of the research implementation extent and quality.

METHODS

Participants were recruited from Nova Scotia, Canada, between January 5 and August 1, 2021. Enrolled participants were randomized into the intervention or control group. Participants randomized to the intervention group received standard care along with the Essential Coaching for Every Mother program’s text messages related to newborn and maternal care for the first 6 weeks after giving birth, while the control group received standard care. Usage data were collected from the SMS text message program used, and participants completed web-based questionnaires at 6 weeks after birth. ﻿Quantitative data and qualitative responses to open-ended questions were used to triangulate findings. Quantitative data were summarized using means, SDs, and percentages, as appropriate, while qualitative data were analyzed using thematic analysis.

RESULTS

Of the 295 unique initial contacts, 150 mothers were eligible and completed the baseline survey to be enrolled in the study (intervention, n=78; control, n=72). Of those randomized into the intervention group, 75 (96%) completed the 6-week follow-up survey to provide feedback on the program. In total, 48 (62%) intervention participants received all messages as designed in the Essential Coaching for Every Mother program, with participants who enrolled late missing on average 4.7 (range 1-12) messages. Intervention participants reported an 89% satisfaction rate with the program, and 100% of participants would recommend the program to other new mothers. Participants liked how the program made them feel, the format, appropriate timing of messages, and content while disliking the frequency of messages and gaps in content. Participants also provided suggestions for future improvement.

CONCLUSIONS

Our process evaluation has provided a comprehensive understanding of interest in the program as well as identified preference for program components. The findings of this study will be used to update future iterations of the Essential Coaching for Every Mother program.

CLINICALTRIAL

ClincalTrials.gov NCT04730570; https://clinicaltrials.gov/ct2/show/NCT04730570
Digital-twin Healthcare: A Gateway to Future Medicine (Preprint)
Authors: Li Zhonghai
Published: January 2022

UNSTRUCTURED

With the development of the world economy and improvements in living standards, people are paying more attention to their healthcare. As simulation is playing an increasingly important role in the field of medicine, providing the individual patient with a customised diagnosis and treatment is envisage as part of future precision medicine. Such customisation will become possible through the emergence of digital twin (DT) technology. As an engineering concept that reflects the true mirror image of a physical entity, the DT is increasingly being used in the field of precision health and personalised medicine. This review summarises the progress of prominent research on DT technology in the medical field and forecasts potential applications and future opportunities and discusses several challenges remaining in digital healthcare. The author hopes that the review encourages additional efforts towards the development and acceptance of DT techniques.
La experiencia migratoria en el proceso de inserción laboral en la zona metropolitana de Guadalajara
Authors: Lutz Ley Arturo
Published: January 2022

Objetivo: averiguar cómo los capitales adquiridos (humano, social, económico y cultural) durante la experiencia migratoria en Estados Unidos influyen en el proceso de inserción laboral en la zona metropolitana de Guadalajara. Metodología: se utilizaron técnicas cualitativas de recolección y análisis de datos. Resultados: los hallazgos indican que, si bien los migrantes regresan con al menos una forma de capital, el mercado laboral limita su uso y los obliga a recurrir a otras estrategias o incluso a cambiar de ramo de trabajo. Limitaciones: una revisión más detallada desde la perspectiva generacional y teniendo presente la edad de quien regresa ayudaría a entender el proceso de inserción laboral. Valor: se analiza dicha inserción en la zona metropolitana de Guadalajara teniendo en cuenta la diversidad de los perfiles de los migrantes y el entorno urbano. Conclusiones: los bajos salarios de México influyen en las estrategias de inserción laboral, y el capital social es importante para quienes regresan.
El Burnout en el personal de Enfermería: ¿De qué manera no quemarse?
Authors: Espinosa-Zepeda M.I , Zarate Grajales R.A. , Fernández-García V.
Published: January 2022

El presente trabajo es una revisión de la literatura sobre los factores de riesgo para la aparición del Síndrome de Burnout en el personal de Enfermería. Este síndrome caracterizado por “agotamiento mental”, “estrés laboral”, “estrés emocional” y “desgaste profesional” , aparece según los estudios revisados como resultado de múltiples factores personales y organizacionales entre los que destacan el estado civil, el género, la edad, la antigüedad laboral, el coeficiente Enfermera paciente y el ambiente físico y organizacional del trabajo. Así también se incluye algunas recomendaciones para que las organizaciones de salud y los profesionales de Enfermería puedan identificar oportunamente el Síndrome de Burnout, prevenir su aparición y definir acciones en consecuencia.
Impacto de la pandemia por COVID-19 en la salud mental
Authors: Morales-Chainé S.
Published: January 2022

El riesgo de contagio por el virus del SARS-CoV-2, causante de la COVID-19, inició en el mundo a finales del 2019 en Hubei, China. Para el momento de esta edición existían más de 176,480,226 personas diagnosticadas con la enfermedad y 3,825,240 fallecidas en el mundo. En México, se reporta una Tasa de Fatalidad por Caso del 9.4% (CFR por sus siglas en inglés).

Referente a la COVID-19, revisiones sistemáticas en la literatura internacional y meta análisis han señalado la prevalencia de otra pandemia asociada a la COVID-19, se trata de los riesgos a la salud mental por el uso de sustancias psicoactivas y las diversas condiciones neurológicas actuales. De acuerdo con Lancet, 17% de 116 países habían referido la necesidad de atender tales condiciones de riesgo relacionadas con la aparición de la COVID-19, desde mediados del 2020.
Uso de Tai Chi para la salud del adulto mayor: revisión bibliográfica
Authors: Cruz-Cartas O. , García-Campos M.L. , Beltrán-Campos V. , Rámirez-Gómez X.S. , Patiño-López M.E. , Jiménez-García S.N.
Published: January 2022

Introducción: La población de adultos mayores está incrementando y se observa la necesidad emergente de implementar estrategias dirigidas a recuperar o conservar su salud para que puedan gozar de una vejez plena. Técnicas como el Tai Chi podrían contribuir, ya que han mostrado tener múltiples beneficios para quien la práctica, tales como mejoras en la concentración, memoria, marcha, equilibrio, reducción del riesgo de caídas, fortalecimiento del sistema cardiovascular, reducción del estrés y la depresión, entre otros beneficios.
Objetivo: Analizar la evidencia científica del uso del Tai Chi para conservar la salud del adulto mayor.
Desarrollo: Revisión bibliográfica realizada durante el periodo 2013-2019 en distintas bases de datos como: Pubmed, Dialnet, SciELO, LILACS, ScienceDirect y Google Académico. Se utilizaron las palabras Tai Chi Chuan, Tai Ji Quan, Tai Chi. Aplicando los criterios de elegibilidad se seleccionaron 29 artículos.
Resultados: Gran porcentaje de los artículos revisados estudian la atención de síntomas físicos que deterioran la movilidad del adulto mayor, sin embargo, también se encontraron investigaciones dirigidas a la parte psicológica, como el estrés, la ansiedad, el insomnio, la depresión y el enfado-tensión, en las cuales la práctica del Tai Chi demostró mejoría.
Conclusiones: El Tai Chi es una terapia alternativa para prevenir y conservar la salud del adulto mayor, fácil de aprender y de bajo costo. En la revisión bibliográfica realizada no se reportan reacciones adversas durante ni después de la práctica de la técnica; el profesional de enfermería puede recomendarla ampliamente para ser implementada como un cuidado dirigido al adulto mayor.
Rol social de la enfermería profesional en la Vicaría de la Solidaridad, Chile 1976–1992
Authors: Ferrada-Herrera R.C. , Rivas-Riveros E.E.
Published: January 2022

Introducción: Durante la dictadura militar en Chile hubo cambios sociales en la política de seguridad social que significaron persecuciones, torturas y muerte de miles de personas, situación que impulsó la creación de la Vicaría de la Solidaridad, la cual implementó distintos programas dentro de los cuales estuvo el área de salud.
Objetivo: Develar el rol social de la enfermería profesional en la Vicaría de la Solidaridad en Chile, años 1976-1992. 
Metodología: Investigación cualitativa, diseño historia de vida, con entrevistas en profundidad a cinco enfermeras y un enfermero, integrantes de la Vicaría, seleccionados por muestreo intencionado. Como sustento teórico, se utilizó la Teoría de Margaret Newman. Se realizó análisis textual y conceptual. Se cumplieron las implicancias éticas y consentimiento informado.
Resultados: Se develan las metacategorías: a) función asistencial, b) función educativa, c) función administrativa y, d) función investigación.
Discusión: La esencia social de la enfermería es la ejecución de acciones coherentes con el contexto en el que se encuentra para favorecer la protección y engrandecimiento de la dignidad humana. Existe coherencia entre los resultados obtenidos y la literatura sobre el tema propuesto.
Conclusión: Las enfermeras se caracterizaron por poseer un profundo compromiso social y deber ético, así como habilidades de observación, coordinación, análisis, liderazgo y toma de decisiones, que las transformaron en agentes de cambio en la población. Este estudio abre una línea de investigación sobre la historia de la enfermería en Chile y su acción social en momentos de crisis.
Factores emocionales asociados al automanejo en personas con diagnóstico de cáncer
Authors: Gutiérrez-Gómez T. , Peñarrieta-de Cordova M.I. , Malibrán-Luque D.J. , Piñones-Martínez M.S. , Cosme-Mendoza M. , Gaspar Meza–de Nalvarte N.
Published: January 2022

Introducción: Las personas con diagnóstico de cáncer y que reciben tratamiento manifiestan factores estresantes, físicos, emocionales y sociales, que inciden en la salud mental del paciente, por lo tanto, se reconoce la importancia de las prácticas de automanejo para aliviar la carga de estos factores.
Objetivo: Identificar factores emocionales que puedan ser útiles para predecir la práctica de automanejo.
Método: Diseño transversal, predictivo, muestreo no probabilístico intencional conformado por 160 personas con diagnóstico de cáncer. Se emplearon los instrumentos: Partners in Health (PIH), Self-rated Health, Escala de depresión del Cuestionario de Salud del Paciente (PHQ-8P), Escala Visual Análoga para valorar el estrés e insomnio. Se aplicó el modelo de regresión lineal múltiple; se calculó el efecto de la diferencia y la potencia estadística utilizando el método de escalonado.
Resultados: Se identificaron dos variables predictoras con significancia estadística (p <.05): problemas para dormir β= -1.310 y trastorno depresivo β= -.440, con una varianza del 10 %, prueba de Durbin-Watson 1,658, tamaño del efecto 0.15 y una potencia de 0.95.
Discusión y Conclusiones: Las personas con cáncer presentan una práctica de automanejo deficiente. Se identificaron factores emocionales que interfieren en este comportamiento: estrés, trastorno depresivo, y problemas para dormir; los dos últimos los factores pueden influir en el automanejo. Se sugiere seguir investigando y profundizar el estudio con el fin de identificar otras barreras asociadas al automanejo, sus diferenciaciones según perfiles sociodemográficos y estadio de la enfermedad.
The Metaphorical World of Sergeу Esenin
Authors:   St. Petersburg Institute of Business and Innovation, Domansky Valery A.
Published: January 2022

The article examines the poetry of S. A. Esenin through an appeal to modern theories of metaphor, analyzes the types of metaphors and the ways of their creation. The author uses concrete examples to show how a metaphor in different periods of the poet’s work determines his image system and concept of the world. Referring to the poet’s specific texts and analyzing the Esenin’s metaphorical world allows us to conclude that the main factor that determines the poet’s individual style is the work of imagination and associative thinking.
Sergey Esenin in the Context of the Epoch: the Results and the Prospects of the Academic Project
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Shubnikova-Guseva Natalia I.
Published: January 2022

The article is devoted to the results of the academic project The Chronicle of the Life and Work of S.A. Esenin in 5 vol. (7 books) (2003–2018), the founder of which was Yu. L. Prokushev, and the prospects of work on The Esenin Encyclopedia. Special attention is paid to the new materials that were first introduced into scientific circulation and reflected in the Chronicle: the poet’s foreign trip to Europe, translations and perception of his poetry abroad etc. Attention is paid to the study of Esenin’s creative heritage as a national and world poet and relevant, littlestudied problems of preparing The Esenin Encyclopedia: revealing the innovation of Esenin’s poetics, the similarity and difference in the perception of his work abroad in Europe and Asia, the CIS countries and the Russian Federation, the study of real and literary toponyms, the connection between poetry and art.
The Starry Esenin: the Exhibition Dedicated to the 125th Anniversary of the Poet in the V. I. Dahl State Museum of the History of Russian Literature
Authors:   State Museum of the History of Russian Literature named after V. I. Dahl, Alekseeva Larisa K.
Published: January 2022

The article reveals the idea, concept and implementation of the exhibition project “Esenin. Live the Way the Star Leads You...” (2020–2021) in the State Museum of the History of Russian Literature named after V. I. Dahl. The museum experience, gained over several decades in the creation of expositions and exhibitions dedicated to the poet, was comprehended and generalized during its preparation. The museum space presents a new aesthetic image of Esenin, corresponding to the needs of the cultural society of the 21th century. The exhibition text is based on the conceptual idea of the “star” hero — a person of a special type of consciousness that has a connection with the Universe. The subjects and the expressive design solution reconfigure the usual optics of the spectator’s perception of the poet’s personality and work and reveal meanings that were not previously revealed or read.
The Esenin’s Perception in the Czech Republic in the 1950–1980’s
Authors:   Institute of Slavic Studies of Russian Academy of Sciences, Amelina Anna V.
Published: January 2022

The article analyses the interpretation of S. A. Esenin’s work by Czech criticism and translations of his works into Czech from the second half of the 1950’s to the 1980’s. During the period 1950’s–1960’s one can observe two obvious ideological “skews” in the perception of Esenin: one of them was created under the influence of the Soviet doctrine, the second represents a view of Esenin exclusively as an avant-garde poet-imaginist. In 1970–1980’s Esenin was the part of the officially permitted layer of culture, his works were actively translated, staged as well as he was ubiquitous both in the studies of literary scholars and in mass periodicals.
The Bibliography of Translations of Works by Sergey Esenin (1920–1927)
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Shubnikova-Guseva Natalia I. , Subbotin Sergey I. ,   А.М. Gorky Institute of World Literature of the Russian Academy of Sciences
Published: January 2022

The presented annotated “The Bibliography of Translations of Works by Sergey Esenin (1920–1927)” is the result of many years of work on the fundamental scientific project “The Chronicle of the Life and Work of S. A. Esenin” in 5 volumes (7 books, 2003–2018). In this work for the first time previously unknown lifetime and posthumous translations of works by Esenin were introduced into scientific circulation and dated. Most of the hard-to-access publications, in cooperation with foreign colleagues, were reviewed de visu. The result of this research is the presented, most comprehensive to date bibliography of the translations of Esenin’s works: from the first, not revealed V. Hartmann’s translations into German (“Autumn” and “Singing Call”) to the numerous posthumous translation 1926–1927. The Bibliography is accompanied by indexes: the poet’s works, the languages of translations and the names of translators. During Esenin’s lifetime his works were translated into 17 languages: German, English, Swedish, French, Italian, Polish, Czech, Bulgarian, Serbian, Slovenian, Ukrainian, Belarusian, Latvian, Armenian, Georgian, Japanese and Yiddish. In total, 205 publications of 93 Esenin’s works (or their fragments) in 21 languages were revealed during the indicated period.
Embodiment & Dance - The importance of movement research through verbal cues in dance improvisation
Authors: Karin Heller-Dani
Published: January 2022

Would a regular guided movement research practice could enhance the experience of free-form dance, in what ways, and why? How would such a practice change or enhance the ways people feel about their movement, their bodies, and their relation to themselves? What sort of verbal cues could be used to guide such an exploratory movement practice?
Conventional coronary bypass remains the gold standard reference technique
Authors: Al_ebrahim Khalid
Published: January 2022

anterior mini‐thoracotomy in multivessel coronary revascularization by
Cyn I read with interest the article, routine minimally invasive
approach via left ak and colleagues1. The main problem of mini anterior
thoracotomy coronary revascularization is the limited or even bad
exposure to the right coronary and posterior obtuse marginal branches
which may affect the quality of the distal anastomosis. This is the most
important technical point of a successful revascularization.
Novos registros do lagarto-listrado Kentropyx paulensis para São Paulo, Brasil
Authors: Queiroz Vinicius Oliveira , Moya Guilherme Marson , Morais Drausio Honório , Medolago Cesar Augusto Bronzatto , Pagotto Thaís , Prist Paula , Abra Fernanda Delborgo , Maffei Fábio
Published: January 2022

O lagarto teídeo endêmico do Cerrado Kentropyx paulensis está classificado nas categorias “Em Perigo” e “Vulnerável” pelas listas do estado de São Paulo e Minas Gerais, respectivamente, sendo, portanto, considerado ameaçado. Com isso, esse trabalho objetivou compilar registros de K. paulensis obtidos em diversos trabalhos realizados no Planalto Ocidental Paulista, que ocupa praticamente metade da área total do Estado de São Paulo, sudeste do Brasil. Foram registradas ocorrências em sete municípios (Anhembi, Assis, Castilho, Jaú, Piracicaba, Quatá e Santa Bárbara d’Oeste) no período quente e chuvoso (dezembro a março) em fitofisionomias que vão desde ambientes naturais como Cerradão e Floresta Estacional Semidecidual até ambientes antropizados como reflorestamentos e pastagens de Urochloa sp. O intenso processo de alteração da paisagem que o Planalto Ocidental Paulista passou no século passado, fruto do modelo econômico que o estado adotou, pode ter colaborado para a diminuição de áreas viáveis para a manutenção dessas populações. Estes novos registros indicam que a ocorrência da espécie pode ser mais ampla, fruto de adaptações às recentes conversões de solo e ambientes naturais ocorridos no Estado de São Paulo.
Potential Human Hair and Sheep Wool Dyeing Characteristics of Hair Colour Formulations Prepared from Four Vegetable Dyes.
Authors:   Department of Chemistry University of Ibadan Ibadan, Nigeria, Oyedeji F.O. , Momoh J.O.
Published: January 2022

Man insatiable desires often leads him to many choices. Some functional, others for the purpose of decoration or acceptability. The dyeing of hair can be comfortably placed in any of the three categories. The production of hair colours is a multi-billion dollar industry that involves the use of both plant-derived and synthetic dyes. Unlike synthetic dyes which can be toxic and harmful to the environment; natural dyes are biodegradable, non-toxic and compatible with environment. In the present study the comparative black – brown colouring effect of seven dye formulations made from ethanol and chloroform extracted pigments of some local dye yielding plants; Lawsonia inermis, Loncocarpus cyanescens, Pterocarpus osun and Trema orientalis on grey human hair and sheep wool was observed and recorded after two hours of dye uptake; storage at room temperature for 4 days and exposure to sunlight for 4 days. % yield of extracted dye ranged from 1.04 - 3.20 in the order Lawsonia inermis < Trema orientalis < Lonchocarpus cyanescens < Pterocarpus osun dye. The colours of the dyes obtained were orange (Lawsonia inermis), yellow (Loncocarpus cyanescens), dark red (Pterocarpus osun) and dark green (Trema orientalis). The human hair took up the dye more readily than the sheep wool and the black-brown colouring effect was maximum with formulation 7 and in the order PF 7>PF 3 > PF 5 > PF 4 > PF 1> PF 6 >P2 with the colour being retained for the greatest period of time at room temperature while fading gradually with the length of exposure to sunlight for both human hair and wool. The colour deepened however for sheep wool, with length of stay at room temperature. In conclusion, the natural dye formulations coloured the hair better than sheep wool, it may therefore be suitable for the formulation of hair colouring solution, after toxicity tests, colour fixing and modification studies have been carried out on the dyes. Keywords: Lawsonia inermis, Loncocarpus cyanescens, Pterocarpus osun, Trema orientalis, Human hair, Sheep wool, Vegetable dyes.
Assessment of Dominative and Integrative Behaviour of Yoruba Language Teachers in Senior Secondary Schools in Oyo State Nigeria
Authors:   Institute of Education University of Ibadan Ibadan, Nigeria, Abijo A.
Published: January 2022

Teacher-student interaction has been a concept that has been researched on for some years now. However, there seem to be paucity of researches that look at the dominative and integrative behaviour of teachers in the classroom. This study therefore was a survey work carried out to assess the integrative and dominative behaviour of Yoruba language teachers in senior Secondary Schools in Oyo State. To attain the objectives of this study, thirty schools were randomly selected from a senatorial district in Oyo State. The Yoruba language teachers of these schools were observed while they taught in the classroom. Three research questions were raised and answered. Data gathered were analyzed using descriptive statistics (frequency, percentage, mean, standard deviation and independent samples t-test). Findings revealed that teachers were generally dominative in their teaching approach in the classroom as most classes were characterized by monologue. Lectures dominated majority of the classes observed. Also, there was no significant statistical difference in the pattern of teacherstudent interaction between private and public school Yoruba language teachers observed. School type did not significantly predict whether a Yoruba language teacher would be dominative or integrative in his or her method of teaching. However, private school Yoruba language teachers had a greater Integrative-Dominative ratio as they encouraged more student-talk in their classrooms. Based on the findings, it was recommended that Yoruba language teachers should try as much as possible to use other teachings methods aside monologue, they should encourage students to ask questions, they should exercise full control over their classrooms and reduce the amount of noise and confusion in their classes. Educational planners and administrators should avail Yoruba language teachers the opportunities of attending seminars, workshops and trainings to keep them abreast with effective methods of teaching. Also, the use of ICT in teaching Yoruba language should be encouraged and teachers who have degrees in the field should be employed and well remunerated. keywords: Assessment, Dominative and Integrative Behaviour, Yoruba Language, Teachers, Senior Secondary Schools
Cybersecurity Risk Management in Identity Systems using Biometric-based Multimodal Authentication.
Authors:   2Faculty of Computational Sciences & Informatics Academic City University College, Accra, Ghana 3Dept of Computer Science Kaduna State University, Kaduna, Nigeria 4Industry Expert ISACA, Ibadan, Nigeria, Talabi A.A. , Longe O.B. , Muhammad A.A. , Olusanya K.
Published: January 2022

This increasing inter-connectivity of systems and dependence on computer and internet-based networks has made Cybersecurity related risks management issues major considerations in designing, developing and managing identity systems. Thus, this paper investigates Cybersecurity and related risk management challenges in Identity Management Systems by undertaking a comparative analysis of different biometric traits. The analysis proved that biometric-based multimodal systems are more secure than uni-modal systems with high accuracy rates. Also, it produced minimal false acceptance and false rejection rates. The biometric-based multi-modal authentication systems will assist organizations to restrict access to authorized users and protect digital assets by ensuring confidentiality, integrity and availability. Keywords: Cybersecurity, Risk, Identity, Biometrics, Multimodal, Behavioural, Fusion
University Teachers’ Use of Twitter as an Instructional Tool and Effective Curriculum Content Implementation in Three Institutions of Higher Leaning in Cross River State Nigeria
Authors:   Dept of Curriculum & Teaching Dept of Environmental Education University of Calabar Calabar-Nigeria, Aglazor Genevieve , Omoogun Modupe Remi
Published: January 2022

This study examined University teachers’ use of twitter as an instructional tool and effective curriculum content implementation in three higher institutions in Cross River State, Nigeria. One purpose of the study was stated and converted into one research question and statement of hypothesis. Literature review was carried out based on the variable understudy and the survey research design was used in the study. The stratified random, purposive and accidental sampling techniques were used in the study. The method of data collection was a 20 items four point rating scale questionnaire. A sample of 373 respondents was used in the study and the reliability index of the instrument was .82 using the Cronbach Alpha Reliability method. The statistical tool for data analysis was the Pearson’s Product Moment Correlation at .05 level of significance. The result of the study showed that there is a significant relationship between University Teachers’ use of Twitter as an instructional tool and effective Curriculum implementation in Universities of Cross River State, Nigeria. Based on the finding of the study, it was recommended that teachers should change the methods and strategies of teaching from traditional methods of chalk and board to communicative strategies like the use of social media like Twitter that are based on the students’ real engagement in the teaching-learning process for effective curriculum implementation. Keywords: Teachers, Twitter, Curriculum implementation,University, Social media
COVID-19 and Family-Owned Business Performance
Authors:   Dept of Bus Admin & Managemen Lagos State Polytechnic, Ikorodu Lagos State, Nigeria, Faseyiku I.O , Balogun K.O , Adegbite M.A.
Published: January 2022

The study examined the impact (COVID-19) pandemic on family owned business (FOBs) in Southwest Nigeria. This study targeted a total population of 23,228 SMEs (SMEDAN, 2017) adopted for FOBs because most SMEs are FOBs in Nigeria. A sample size of three hundred and seventy eight 378 respondents from the total population constitutes the sample size for questionnaire that was administered. The determination of sample size for the study was achieved using the Raosoft sample size estimator. Out of the 378 questionnaire being distributed, only 250 were filled and returned appropriately. The study adopted multistage sampling technique. The focus of the study was based on fast moving consumable goods (FMCGs) producers of essential goods. The collected data was scored, tabulated, coded, and analyzed using multiple linear regression analysis with the aid of SPSS 23.0., the result reveals that there is a moderate significant relationship between COVID-19 pandemic and FOBs performance, where product patronage (r = 0.534, P< 0.01); growth (r= 0.623, P< 0.01), and profitability (r = 0.228, P< 0.01). Therefore, the study accepted the alternative hypothesis that there is a significant relationship exist between COVID-19 pandemic and FOBs performance. The study recommended that government should strengthen the business related incentive packages and circulate the information noticeably, this is indispensable in volatile potential of the Covid-19 pandemic predicament; FOBs should identify critical business issues and develop recovery strategy such as business recovery plan (BRP) to enable them mitigates the impact of covid-19 on their businesses; and opportunities should always tap from every situation by businesses. Keywords: COVID-19 Pandemic, FOBs Performance, Product Patronage, Growth, Profitability
Aplicativos de musculação como dispositivos biopolíticos de educação do corpo
Authors: Soares Carleane , Ribeiro Filipe Santos , Zoboli Fabio
Published: January 2022

O presente ensaio tem como objetivo interpelar os aplicativos de musculação como espaços contemporâneos de educação do corpo na medida em que atuam como dispositivos biopolíticos de controle e produção de corpos padronizados. Para sustentar tal argumento reflexionamos a partir de dois aplicativos de musculação que se enquadram na categoria denominada “saúde e fitness”; são eles: “BodBot Personal Trainer” e “Exercícios em Casa – Sem Equipamentos”. Concluímos que esses dispositivos têm poderes apelativos que visam à homogeneização das condutas corporais, à normalização do corpo e o governo de si. Ou seja, grosso modo, são dispositivos biopolíticos.
O programa Aprendizagem na Idade Certa (Paic) segundo artigos acadêmicos brasileiros
Authors: Bravo Maria Helena de Aguiar , Ribeiro Vanda Mendes , Cruz Maria do Carmo Meirelles Toledo
Published: January 2022

Este texto tem por objetivo analisar 39 artigos acadêmicos selecionados na base Scielo, em abril de 2020, que tratam do Programa Aprendizagem na Idade Certa (Paic) e compreender de que forma a literatura vem se apropriando do tema à luz de categorias da ciência política que visam traduzir as fases das políticas públicas, bem como identificar as instituições e localidades que o estudam, a temporalidade da produção e analisar seus principais objetivos. As palavras-chave de busca foram Ceará e Paic. Conclui-se que o Paic vem sendo estudado em contexto nacional e internacional, com pesquisadores associados a diversas instituições públicas, privadas e não governamentais. Observou-se a ampliação da produção científica ao longo dos anos. Destaca-se o foco dos pesquisadores sobre a fase de formulação do Paic e de suas estratégias e também sobre a fase da avaliação, neste caso, para compreender seus efeitos e resultados de aprendizagem dos alunos.
A formação integral e o desenvolvimento das habilidades socioemocionais frente à prevenção de ocorrência de casos de bullying nas escolas
Authors: Sanzovo Alessandra Rodrigues de Freitas , Santos Cruz José Anderson
Published: January 2022

O objetivo desta pesquisa é demonstrar o quanto uma formação integral de qualidade pode possibilitar o desenvolvimento de habilidades socioemocionais. Uma formação que visa não só deixar os alunos o dia todo na escola, mas, principalmente, trazer uma educação significativa que possibilite que ele vivencie o seu dia a dia nos estudos com uma matriz curricular ampliada. Ao desenvolver habilidades socioemocionais, estes indivíduos se tornam seres mais empáticos e sensíveis às causas do outro e, também, seres passíveis de entender, aceitar e se envolver com demandas de inclusão, respeito e solidariedade. A pesquisa, ainda, traz reflexões de como a escola pode ser um complemento dos déficits familiares na formação de valores morais, valores éticos e consciência de respeito ao outro. Neste contexto, dentro de um novo modelo educacional, é possível verificar o quanto este aluno-cidadão se torna mais consciente e entendedor de práticas que podem agredir o outro. Uma escola que forma os alunos não só com conteúdo de uma matriz curricular engessada, mas num propósito de consciência da importância de conhecer e lutar por causas sociais, causas de inclusão e respeito a todos, com certeza é o modelo de escola mais contemporâneo que podemos ter. Consequentemente, diante deste cenário escolar, a pesquisa visa demonstrar o quanto este cenário é capaz de prevenir, reduzir e, quiçá, acabar com os casos de bullying nas escolas e na vida, já que a escola forma para além muros escolares.
The spectrum of a new class of Sylvester-Kac matrices
Authors: Alazemi Abdullah , da Fonseca , Kılıç Emrah
Published: January 2022

We define a new class of Sylvester-Kac matrices and calculate their spectra
explicitly. We use the technique of the left eigenvectors to obtain the
claim. We also provide some right eigenvectors which can be useful in
applied computations. The main results are rather general and contain many
known particular characterizations. Matrices belonging to this family
represent a convenient test matrices for numerical eigenvalue computations
with known spectrum.
Primary Prevention of Cardiovascular and Heart Failure Events With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Their Combination in Type 2 Diabetes
Authors: Wright Alison K. , Carr Matthew J. , Kontopantelis Evangelos , Leelarathna Lalantha , Thabit Hood , Emsley Richard , Buchan Iain , Mamas Mamas A. , van Staa Tjeerd P. , Sattar Naveed , Ashcroft Darren M. , Rutter Martin K.
Published: January 2022

OBJECTIVE

To assess associations between current use of sodium–glucose cotransporter 2 inhibitors (SGLT2is), glucagon-like peptide 1 receptor agonists (GLP-1RAs), and their combination and risk for major adverse cardiac and cerebrovascular events (MACCE) and heart failure (HF) in people with type 2 diabetes.

RESEARCH DESIGN AND METHODS

In three nested case-control studies involving patients with type 2 diabetes in England and Wales (primary care data from the Clinical Practice Research Datalink and Secure Anonymised Information Linkage Databank with linkage to hospital and mortality records), we matched each patient experiencing an event with up to 20 control subjects. Adjusted odds ratios (ORs) for MACCE and HF among patients receiving SGLT2i or GLP-1RA regimens versus other combinations were estimated using conditional logistic regression and pooled using random-effects meta-analysis.

RESULTS

Among 336,334 people with type 2 diabetes and without cardiovascular disease, 18,531 (5.5%) experienced a MACCE. In a cohort of 411,206 with type 2 diabetes and without HF, 17,451 (4.2%) experienced an HF event. Compared with other combination regimens, the adjusted pooled OR and 95% CI for MACCE associated with SGLT2i regimens was 0.82 (0.73, 0.92), with GLP-1RA regimens 0.93 (0.81, 1.06), and with the SGLT2i/GLP-1RA combination 0.70 (0.50, 0.98). Corresponding data for HF were SGLT2i 0.49 (0.42, 0.58), GLP-1RA 0.82 (0.71, 0.95), and SGLT2i/GLP-1RA combination 0.43 (0.28, 0.64).

CONCLUSIONS

SGLT2i and SGLT2i/GLP-1RA combination regimens may be beneficial in primary prevention of MACCE and HF and GLP-1RA for HF. These data call for primary prevention trials using these agents and their combination.
Primary Prevention of Cardiovascular and Heart Failure Events With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Their Combination in Type 2 Diabetes
Authors: Wright Alison K , Carr Matthew J , Kontopantelis Evangelos , Leelarathna Lalantha , Thabit Hood , Emsley Richard , Buchan Iain , Ashcroft Darren M , Rutter Martin K
Published: January 2022

Objective:
To assess associations between current use of
SGLT2i, GLP-1RA and their combination and risk for MACCE and heart failure (HF)
in people with type 2 diabetes.

Research
Design and Methods: In three nested case-control studies involving
people with type 2 diabetes in
England and Wales (primary care data from CPRD and SAIL Databank with linkage
to hospital and mortality records), we matched each patient experiencing an
event with up to 20 controls. Adjusted odds ratios for MACCE
and HF among patients receiving SGLT2i or GLP-1RA regimens vs other
combinations were estimated using conditional logistic regression and
pooled using random-effects meta-analysis.

Results:
Among 336,334 people with type 2 diabetes
and without cardiovascular disease, 18,531 (5.5%) experienced a MACCE. 17,451
(4.2%) experienced a HF event in a cohort of 411,206 with type 2
diabetes and without HF. Compared with other combination regimens, the
adjusted pooled odds ratio and 95% confidence interval (CI) for MACCE
associated with SGLT2i regimens was 0.82 (95% CI 0.73-0.92);
with GLP-1RA regimens 0.93 (95% CI 0.81-1.06), and with the
SGLT2i/GLP-1RA combination 0.70 (95% CI 0.50-0.98).
Corresponding data for HF were: SGLT2i, 0.49 (95% CI 0.42-0.58);
GLP-1RA, 0.82 (95% CI 0.71-0.95);
and SGLT2i/GLP-1RA combination, 0.43 (95% CI
0.28-0.64).

Conclusions: SGLT2i and SGLT2i/GLP-1RA combination regimens may
be beneficial in primary prevention of MACCE and heart failure and GLP-1RA for heart
failure. These data call for primary prevention trials using these agents and
their combination.
pdx1 Knockout Leads to a Diabetic Nephropathy-Like Phenotype in Zebrafish and Identifies Phosphatidylethanolamine as Metabolite Promoting Early Diabetic Kidney Damage
Authors: Wiggenhauser Lucas M. , Metzger Lena , Bennewitz Katrin , Soleymani Silas , Boger Mike , Tabler Christoph T. , Hausser Ingrid , Sticht Carsten , Wohlfart Paulus , Volk Nadine , Heidenreich Elena , Buettner Michael , Hammes Hans-Peter , Kroll Jens
Published: January 2022

The pdx1-/- zebrafish mutant was recently established as a novel animal model of
diabetic retinopathy. Here, we investigate whether knockout of pdx1 also
leads to diabetic kidney disease (DKD). pdx1-/- larvae
exhibit several signs of early DKD such as glomerular hypertrophy, impairments
in the filtration barrier corresponding to microalbuminuria and glomerular
basement membrane (GBM) thickening. Adult
pdx1-/- mutants show progressive GBM thickening in comparison
to the larval state. Heterozygous pdx1
knockout also leads to glomerular hypertrophy as initial establishment of DKD similar
to the pdx1-/- larvae. RNA
sequencing (RNA-seq) of adult pdx1+/-
kidneys uncovered regulations in multiple expected diabetic pathways related to
podocyte disruption and hinting at early vascular dysregulation without obvious
morphological alterations. Metabolome analysis and pharmacological intervention
experiments revealed the contribution of phosphatidylethanolamine (PtdE) in the
early establishment of kidney damage. In
conclusion, this study identified the pdx1
mutant as a novel model for the study of DKD showing signs of the early disease
progression already in larval stage and several selective features of later DKD
in adult mutants.