bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of a Web-Based Medication Reconciliation Application Within a Primary Care Setting: Cluster-Randomized Controlled Trial
Authors: Gionfriddo Michael R , Hu Yirui , Maddineni Bhumika , Kern Melissa , Hayduk Vanessa , Kaledas William R , Elder Nevan , Border Jeffrey , Frusciante Katie , Kobylinski Maria , Wright Eric A
Published: January 2022

Background

Despite routine review of medication lists during patient encounters, patients’ medication lists are often incomplete and not reflective of actual medication use. Contributing to this situation is the challenge of reconciling medication information from existing health records, along with external locations (eg, pharmacies, other provider/hospital records, and care facilities) and patient-reported use. Advances in the interoperability and digital collection of information provides a foundation for integration of these once disparate information sources.

Objective

We aim to evaluate the effectiveness of and satisfaction with an electronic health record (EHR)-integrated web-based medication reconciliation application, MedTrue (MT).

Methods

We conducted a cluster-randomized controlled trial of MT in 6 primary care clinics within an integrated health care delivery system. Our primary outcome was medication list accuracy, as determined by a pharmacist-collected best-possible medication history (BPMH). Patient and staff perspectives were evaluated through surveys and semistructured interviews.

Results

Overall, 224 patients were recruited and underwent a BPMH with the pharmacist (n=118 [52.7%] usual care [UC], n=106 [47.3%] MT). For our primary outcome of medication list accuracy, 8 (7.5%) patients in the MT arm and 9 (7.6%) in the UC arm had 0 discrepancies (odds ratio=1.01, 95% CI 0.38-2.72, P=.98). The most common discrepancy identified was patients reporting no longer taking a medication (UC mean 2.48 vs MT mean 2.58, P=.21). Patients found MT easy to use and on average would highly recommend MT (average net promoter score=8/10). Staff found MT beneficial but difficult to implement.

Conclusions

The use of a web-based application integrated into the EHR which combines EHR, patient-reported data, and pharmacy-dispensed data did not improve medication list accuracy among a population of primary care patients compared to UC but was well received by patients. Future studies should address the limitations of the current application and assess whether improved implementation strategies would impact the effectiveness of the application.
Effects of Social Media Use for Health Information on COVID-19–Related Risk Perceptions and Mental Health During Pregnancy: Web-Based Survey (Preprint)
Authors: Wang Qian , Xie Luyao , Song Bo , Di Jiangli , Wang Linhong , Mo Phoenix Kit-Han
Published: January 2022

BACKGROUND

Social media has become an important source of health information during the COVID-19 pandemic. Very little is known about the potential mental impact of social media use on pregnant women.

OBJECTIVE

This study aims to examine the association between using social media for health information and risk perception for COVID-19, worry due to COVID-19, and depression among pregnant women in China.

METHODS

A total of 4580 pregnant women were recruited from various provinces of China. The participants completed a cross-sectional, web-based survey in March 2020.

RESULTS

More than one-third (1794/4580, 39.2%) of the participants reported always using social media for obtaining health information. Results of structural equation modeling showed that the frequency of social media use for health information was positively associated with perceived susceptibility (β=.05; P<.001) and perceived severity (β=.12; P<.001) of COVID-19, which, in turn, were positively associated with worry due to COVID-19 (β=.19 and β=.72, respectively; P<.001). Perceived susceptibility (β=.09; P<.001), perceived severity (β=.08; P<.001), and worry due to COVID-19 (β=.15; P<.001) all had a positive association with depression. Bootstrapping analysis showed that the indirect effects of frequency of social media use for health information on both worry due to COVID-19 (β=.09, 95% CI 0.07-0.12) and depression (β=.05, 95% CI 0.02-0.07) were statistically significant.

CONCLUSIONS

This study provides empirical evidence on how social media use for health information might have a negative impact on the mental health of pregnant women. Interventions are needed to equip this population with the skills to use social media properly and with caution.
Factors contributing to physicians’ current use and satisfaction of electronic health records (EHRs) in Kuwait’s public health care: A cross- sectional study. (Preprint)
Authors: Alotaibi Jawaher , Tolma Eleni , Alali Walid , Alhuwail Dari , Al -Junid Syed
Published: January 2022

BACKGROUND

The Electronic Health Record (EHR) is the backbone of the integration of information to help physicians in making effective decisions in patient care. The adoption of E-health care system, Health Information Communication Technologies (HICT) and EHR is raising in Kuwait

OBJECTIVE

This study aims to (i) identify the factors associated with physician’s current use, satisfaction, and prevalence with EHRs (ii) assess the factors’ relative importance in terms of predicting current use, satisfaction and prevalence with EHRs.

METHODS

This study took place at a public hospital in 2019. Using an anonymous self-administered paper-based survey, two hundred and ninety-five physicians were recruited. The survey contained 35 statements and the Technology Acceptance Model was used as the theoretical framework to guide the survey development. The dependent variables were “Physicians' current use of EHR" and “Physicians’ Satisfaction with EHR.” The independent variables were the demographics factors, Length of use of EHR, training quality, perceptions of barriers toward using EHR, the EHR effect on physicians’ Work, and level of ease of EHR function. Descriptive analysis, followed by bivariate, and multivariate linear regression adjusted for demographics were conducted.

RESULTS

Among the 295 research participants, 75% indicated that they are currently using the EHR system. The effect that the EHR use had on physician’s work was the most significant predictor of physician’s satisfaction using EHR (β=.377, p=0.000), followed by the level of ease of EHR function and (β=.341, p=.00) and barriers to using EHR (β=.170, p=0.000). Regarding the prediction of the current use of EHR it was found that the perceptions of barriers to using EHR was the most significant predictor (β= .145, p=0.000) followed by the effect on physician’s work (β=.645, p=0.01) and length of EHR (β= .111, p=0.03).

CONCLUSIONS

In the promotion of EHR current use and related satisfaction, enhancing and promoting the positive effect of EHR use on the physicians’work while making the implementation of the EHR system as easy as possible by removing barriers seem to be key factors.

CLINICALTRIAL

Not applicable .
A Framework for Femtech: Guiding Principles for Developing Digital Reproductive Health Tools in the United States (Preprint)
Authors: Krishnamurti Tamar , Birru Talabi Mehret , Callegari Lisa S , Kazmerski Traci M , Borrero Sonya
Published: January 2022

UNSTRUCTURED

The United States has abysmal reproductive health indices that, in part, reflect stark inequities experienced by people of color and those with preexisting medical conditions. The growth of “femtech,” or technology-based solutions to women’s health issues, in the public and private sectors is promising, yet these solutions are often geared toward health-literate, socioeconomically privileged, and/or relatively healthy white cis-women. In this viewpoint, we propose a set of guiding principles for building technologies that proactively identify and address these critical gaps in health care for people from socially and economically marginalized populations that are capable of pregnancy, as well as people with serious chronic medical conditions. These guiding principles require that such technologies: (1) include community stakeholders in the design, development, and deployment of the technology; (2) are grounded in person-centered frameworks; and (3) address health disparities as a strategy to advance health equity and improve health outcomes.
Does off-hours endoscopic hemostasis affect outcomes of nonvariceal upper gastrointestinal bleeding?
Authors: Guan Jia-Lun , Wang Ge , Fang Dan , Han Ying-Ying , Wang Mu-Ru , Tian De-An , Li Pei-Yuan
Published: January 2022

Aim:
Different researches showed controversial results about the ‘off-hours effect’ in nonvariceal upper gastrointestinal bleeding (NVUGIB).
Materials & methods:
A total of 301 patients with NVUGIB were divided into regular-hours group and off-hours group based on when they received endoscopic hemostasis, and the relationship of the clinical outcomes with off-hours endoscopic hemostasis was evaluated.
Results:
Patients who received off-hours endoscopy were sicker and more likely to experience worse clinical outcomes. Off-hours endoscopic hemostasis was a significant predictor of the composite outcome in higher-risk patients (adjusted OR: 4.63; 95% CI: 1.35–15.90). However, it did not associate with the outcomes in lower-risk patients.
Conclusion:
Off-hours effect may affect outcomes of higher-risk NVUGIB patients receiving endoscopic hemostasis (GBS ≥12).
EVROPSKA UNIJA KAO AKTER U MEĐUNARODNIM ODNOSIMA: MOĆ DISKURSA
Authors: Vukasovic Dejana
Published: January 2022

U savremenoj akademskoj literaturi postoji mnoštvo definicija koje nastoje da ukažu na specifičnost EU kao aktera u međunarodnim odnosima. U ovom radu, autorka se oslanja na poststrukturalističko stanovište u međunarodnim odnosima, te polazi od stava da EU ne poseduje prediskurzivan identitet, već je njen identitet izgrađen kroz diskurs. U skladu sa poststrukturalističkim stanovištem, autorka zastupa stav da identitet EU zahteva “spoljašnjeg drugog” koga istovremeno i konstruiše. Rad je stoga usmeren na moć koja se nalazi u osnovi odnosa „ja–drugi”, te na predstave i prakse koje omogućavaju izgradnju superiornosti i inferiornosti u ovom odnosu. U prvom delu rada predstavljaju se osnove poststrukturalističkog stanovišta u međunarodnim odnosima i studijama evropske integracije. Drugi i treći deo rada analiziraju diskurse EU kao zajednice vrednosti i globalnog aktera. U fokusu analize su izjave zvaničnika EU i strateška dokumenta koja definišu EU kao aktera na međunarodnoj sceni. Kroz ove diskurse, EU proizvodi „znanje” o svojoj superiornosti u odnosu na spoljašnje druge, čime se obezbeđuje legitimitet reprezentativnih praksi. Zaključuje se da diskurzivna konstrukcija EU kao aktera u međunarodnim odnosima nužno ne zahteva konstruisanje drugog kao radikalno različitog, sa jasnim granicama između EU i drugih, već da i izgradnja fluidnih granica između EU i njenih ambivalentnih drugih može takođe dovesti do delovanja EU kao modernog aktera, nalik državi.
POLITIČKA BORBA OKO POJMOVA: KRIZA DEMOKRATIJE
Authors: Petrovic Luka
Published: January 2022

Sveprisutnost reči kriza ne samo u svakodnevnom govoru, već i u akademskim radovima, nije ispraćena adekvatnim određenjem značenja reči. U prvom delu teksta autor nastoji da prikaže promene značenja reči kriza tokom istorije, argumentujući da kriza ne mora nužno imati negativnu konotaciju, već da može predstavljati priliku za promenu. U drugom delu teksta autor istražuje šta se podrazumeva pod pojmom „kriza demokratije“, pri čemu zastupa tezu da su tokom dvadesetog veka različiti autori, zavisno od svojih normativnih i političkih pozicija, pod time podrazumevali različite stvari, nudeći sasvim drugačija rešenja za krizu demokratije. Za objektivno stanje predlagana su različita subjektivna rešenja za prevazilaženje krize, što ilustruje da „demokratija“ i „kriza demokratije“ nemaju fiksirano značenje, već zavise od društvenog i političkog konteksta.
EVOLUCIJA ULOGE PREDSEDAVAJUĆEG SAVETA MINISTARA EVROPSKE UNIJE
Authors: Todorovic Lazic Jelena
Published: January 2022

Savet ministara Evropske unije predstavlja centralnu instituciju za donošenje odluka u Uniji, bilo samostalno ili zajedno sa Evropskim parlamentom. Jedan od važnih elemenata u okviru Saveta jeste predsedavanje, odnosno rukovođenje celokupnim aktivnostima Unije. U toj ulozi, nalazi se Predsedavajući (Presidency) -države članice EU koje se smenjuju po principu šestomesečne rotacije. Ova uloga je tokom više od šest decenija postojanja evoluirala u značajnoj meri te je cilj ovog naučnog rada da pokuša da prikaže put koji je Predsedavajući prešao od osnivanja Evropskih zajednica do danas. Akcenat je na Ugovoru iz Lisabona koji je u ovom segmentu doneo novine. Takođe, u radu će biti izloženi i neki interesantni primeri iz istorije rotirajućeg predsedavanja Savetom ministara.
HLADNI RAT I DRŽAVOCENTRIČNI KONCEPT BEZBEDNOSTI: ISKUSTVA I PARALELE
Authors: Jevtic Dragan , Radojevic Slobodan
Published: January 2022

U radu se obrađuje tema Hladnog rata kao posebnog sistema međunarodnih odnosa u periodu od 1945. do 1991. godine, koncept bezbednosti i odnosi velikih sila i blokova. Struktura međunarodnog sistema tokom Hladnog rata bila je bipolarna, pošto nije bilo dovoljno jakih drugih velikih sila da organizuju multipolarni sistem. Postojale su i države koje su bile izvan domašaja supersila, ali je preovlađujuća struktura međunarodnog sistema bila bipolarna. Procedure koje su bile opšte prihvaćene su zastrašivanje (odvraćanje) i upravljanje krizama da ne bi eskalirale u nuklearni sukob širih razmera. Hladni rat kao poseban međunarodni sistem oličen je dominantnim okvirom u kome se organizuju i dešavaju međunarodni poslovi ali i unutrašnja politika, koji ne oblikuje sve ali oblikuje mnoge stvari. Koncept bezbednosti u Hladnom ratu bio je državocentrični. Autori stoga analizirajući Hladni rat i državocentrični koncept bezbednosti zaključuju da se danas u vreme multipolarnog sveta pojavljuju njegovi „obrisi“, a katkad se stiče utisak da još uvek traje sa svim svojim obeležjima i principima. U godini u kojoj se obeležava trideset godina od zvaničnog kraja Hladnog rata (raspad SSSR decembra 1991. godine) autori skreću pažnju naučne i stručne javnosti na važnost njegovog proučavanja i rezimiranje iskustava i paralela.
USPON KRAJNJE DESNICE U SUSEDSTVU
Authors: Bursac Dejan
Published: January 2022

Prikaz knjige:
Peter Kreko, Attila Juhasz. 2017. The Hungarian Far Right: Social Demand, Political Supply, and International Context. Stuttgart: Ibidem-Verlag, p. 267.
EVROPA, JEDAN CILJ, JEDNA SUDBINA
Authors: Todorovic Lazic Jelena
Published: January 2022

Prikaz knjige:
Foucher, Michele. 2019. L’Europe, un dessein, un destin. Paris: Edition Marie B, 126 str.
HIBRIDNA POSTMODERNIZACIJA SOCIJALNOG RADA
Authors: Stojanovic Djordje , Zekavica Biljana
Published: January 2022

U ovome radu se raspravlja intenzitet, forma i stepen osvešćenosti postmodernizacije socijalnog rada. U tom smislu, pod postmodernizacijom socijalnog rada se podrazumeva njegovo diskurzivno/metanarativno smeštanje u kontekst globalno postmodernizovanih društva, kako na nivou spoljne institucionalne mreže značenja, tako i na nivou unutrašnjeg rekonfigurisanja, reformulisanja, redefinisanja i reorganizovanja po novim, postmodernim, načelima, agendama i zahtevima. Međutim, to ne znači apsorbovanje nekim drugim metanarativom, već formulisanje autentičnog metanarativa socijalnog rada. Objašnjenje posmodernosti i postmodernizacije ne mora nužno biti deo „intelektualno-spekulativneˮ sfere postmodernizma, modernističke teorije mogu biti integrisane sa postmodernističkim diskurzivnim protokolima u svrhu hibridnog objašnjenja nekog odnosnog fenomena. Takav stav/pozicija se afirmiše preko propitivanja/dekonstrukcije TIME/TIME modela i odnosa neoliberalnog metanarativa i metanarativa socijalnog rada.
O NADLEŽNOSTI ZA DONOŠENJE MERA TOKOM VANREDNOG STANJA – POVODOM ODLUKE USTAVNOG SUDA SRBIJE
Authors: Markovic Djordje
Published: January 2022

Tokom prošlogodišnjeg vanrednog stanja, zbog nemogućnosti da se Narodna skupština sastane, Vlada Republike Srbije je uz supotpis predsednika Republike, donela Uredbu kojom je trebalo da propiše mere odstupanja od ljudskih i manjinskih prava kako bi se što efikasnije izašlo na kraj sa epidemijom virusa korona. Nekoliko dana kasnije ministar unutrašnjih poslova je doneo Naredbu na osnovu ovlašćenja sadržanih u uredbi. U oktobru 2020. godine, Ustavni sud Srbije je cenio ustavnost pomenute Uredbe. Predmet ovog rada predstavlja tumačenje ustavnih odredbi koje se tiču propisivanja mera kojima se odstupa od ljudskih i manjinskih prava tokom vanrednog stanja, kao i ocena aktivnosti i pravnih stavova Vlade, Ministarstva unutrašnjih poslova i Ustavnog suda. Cilj rad je da ukažemo na nedoumice koje postoje u našem pravnom sistemu u ovoj materiji, i predložimo drugačiji pristup od onoga koji su ponudili najviši državni organi, kako bi se u nekoj budućoj situaciji postupalo u skladu sa ustavotvorčevom voljom i eventualno popunile postojeće pravne praznine i otklonile nedorečenosti. U radu je pored pozitivnopravnog korišćen i uporedno-pravni metod, analizirane su dve odluke Ustavnog suda, upotrebljena je savremena literatura iz navedene oblasti, ali su konsultovani i klasični pravni i politikološki tekstovi. Sažeto, glavni zaključak rada je da su Vlada i predsednik Republike postupili suprotno izričitoj ustavnoj normi, a da je Ustavni sud propustio da takav akt sankcioniše.
Redes de colaboración institucional en la implementación de la Estrategia Nacional para la Prevención y el Control del Sobrepeso, la Obesidad y la Diabetes 2013-2018
Authors: Moreno González Mario
Published: January 2022

La Estrategia Nacional para la Prevención y el Control del Sobrepeso, la Obesidad y la Diabetes (ENPCSOD) 2013 – 2018, buscó atender esta problemática compleja y grave a través de un mecanismo de colaboración institucional que, visto desde el paradigma del Análisis de Redes Sociales (ARS), permitió analizar la relación entre instituciones y objetivos estratégicos, donde las de carácter privado mostraron un ligero predominio e incidencia sobre las regulaciones. Partiendo de esta observación se exponen los defectos y alcances de esta política, sometiendo a debate el replanteamiento y estructuración de una nueva estrategia impulsada por la actual administración y asociaciones sociales.
The effects of applying filters on EEG signals for classifying developers’ code comprehension
Authors: Gonçales Lucian Jose , Farias Kleinner , Kupssinskü Lucas , Segalotto Matheus
Published: January 2022

EEG signals are a relevant indicator for measuring aspects related to human factors in Software Engineering. EEG is used in software engineering to train machine learning techniques for a wide range of applications, including classifying task difficulty, and developers’ level of experience. The EEG signal contains noise such as abnormal readings, electrical interference, and eye movements, which are usually not of interest to the analysis, and therefore contribute to the lack of precision of the machine learning techniques. However, research in software engineering has not evidenced the effectiveness when applying these filters on EEG signals. The objective of this work is to analyze the effectiveness of filters on EEG signals in the software engineering context. As literature did not focus on the classification of developers’ code comprehension, this study focuses on the analysis of the effectiveness of applying EEG filters for training a machine learning technique to classify developers' code comprehension. A Random Forest (RF) machine learning technique was trained with filtered EEG signals to classify the developers' code comprehension. This study also trained another random forest classifier with unfiltered EEG data. Both models were trained using 10-fold cross-validation. This work measures the classifiers' effectiveness using the f-measure metric. This work used the t-test, Wilcoxon, and U Mann Whitney to analyze the difference in the effectiveness measures (f-measure) between the classifier trained with filtered EEG and the classifier trained with unfiltered EEG. The tests pointed out that there is a significant difference after applying EEG filters to classify developers' code comprehension with the random forest classifier. The conclusion is that the use of EEG filters significantly improves the effectivity to classify code comprehension using the random forest technique.
Projection of land use to 2030 and its impacts on water availability in a brazilian sub-basin: A LCM and SWAT approach
Authors: Paulo de Sousa Oliveira Adriana , Ribeiro Gracelli Rafaela , Amaral e Silva Arthur , Juste dos Santos Vitor , De Siqueira Castro Jackeline , Calijuri Maria Lúcia
Published: January 2022

Changes in land use and land cover (LULC) can result in significant changes in a hydrographic ba- sin flow regime. Future projections about LULC and its interference with water availability help to identify extreme events in advance and help propose appropriate management measures. Thus, this study aimed to make the LULC projection for the year 2030 for the Alto Rio Grande (ARG) sub- basin, located in Southeastern Brazil. This region was chosen because of its intense water resources use and for having recently faced water scarcity as result of prolonged droughts and inadequate water resources management. To identify the LULC trend for the year 2030, the Land Change Modeler (LCM) was used, the map obtained was inserted in the Soil and Water Assessment Tool (SWAT) model previously calibrated and validated for the region’ environmental and climatic conditions. The ARG sub-basin was affected by heavy rains in 2011, which resulted in changes in the landscape due to landslides. This particularity of the region contributed to the projection of LULC for the year 2030 to present an increase in forest and pastures to the agricultural areas detriment. When evaluating the impacts of these changes in water availability, it was observed that the SWAT model presented, for the same rainfall conditions, a reduction in peak streamflows of up to 59% and a reduction in the average monthly flow of up to 63% in 2030 in relation to the LULC observed in 2017. Thus, this study provides an important contribution by identifying a considerable reduction in water availability. These results will help to formulate strategies for water resources management and the adoption of measures to promote water security in the region.
A Conceptual Model for Situating Purposes in Artificial Institutions
Authors: Cunha Rafhael R. , Hübner Jomi Fred , De Brito Maiquel
Published: January 2022

{In multi-agent systems, artificial institutions connect institutional concepts, belonging to the institutional reality, to the concrete elements that compose the system. The institutional reality is composed of a set of institutional concepts, called Status-Functions. Current works on artificial institutions focus on identifying the status-functions and connecting them to the concrete elements. However, the functions associated with the status-functions are implicit. As a consequence, the agents cannot reason about the functions provided by the elements that carry the status-functions and, thus, cannot exploit these functions to satisfy their goals. Considering this problem, this paper proposes a model to express the functions -- or the purposes -- associated with the status-functions. Examples illustrate the application of the model in a practical scenario, showing how the agents can use purposes to reason about the satisfaction of their goals in institutional contexts.
Efficient Breast Cancer Classification Using Histopathological Images and a Simple VGG
Authors: Filho Marcelo Luis Rodrigues , Cortes Omar Andres Carmona
Published: January 2022

Breast cancer is the second most deadly disease worldwide. This severe condition led to 627,000 people dying in 2018. Thus, early detection is critical for improving the patients' lifetime or even curing them. In this context, we can appeal to Medicine 4.0, which exploits machine learning capabilities to obtain a faster and more efficient diagnosis. Therefore, this work aims to apply a simpler convolutional neural network, called VGG-7, for classifying breast cancer in histopathological images. Results have shown that VGG-7 overcomes the performance of VGG-16 and VGG-19, showing an accuracy of 98%, a precision of 99%, a recall of 98%, and an F1 score of 98%.
MANAJEMEN KOMUNIKASI PELAKSANAAN OPERASI AMAN NUSA II MADAGO RAYA 2021 POLRES SIGI DALAM PERCEPATAN DAN ANTISIPASI WABAH COVID-19
Authors: Suriady Israwaty , Ningsih Fitriani Puspa , Nurhaidar
Published: January 2022

This article is based on the spread of the Covid-19 outbreak in Indonesia, including in the Central Sulawesi Province. In response to this, the government took various steps to handle and prevent the outbreak, one of which was implemented through the establishment of the Task Force for the Acceleration of Handling the Covid-19 Outbreak at the District and District Levels. In the Sigi Regency area, this task force works under the auspices of the Safe Operations Task Force Nusa II Madago Raya. Involving elements of the Police, TNI, and other related elements, this operation program has carried out various activities in an effort to deal with Covid-19 in the Sigi Regency area. Using qualitative methods, this study aims to see how the communication management of the Aman Nusa Madago Raya II operation of the Sigi Police Station is. The results of the study found four important stages in communication management which were described quite well in the implementation of the program.
PERSEPSI TENTANG RISIKO BREAKTHROUGH INFECTION COVID-19 DALAM LINGKUNGAN HEALTH RISK MESSAGES
Authors: Pradekso Tandiyo , Setyabudi Djoko
Published: January 2022

The Covid-19 vaccination rate continues to increase, it is important to pay attention to the possibility of a breakthrough infection, which is a viral infection that occurs after a person has been vaccinated. This is a case that is expected to occur in some of those who have received the vaccine, as no vaccine for any disease is 100 percent effective. During the time of living in this period of the Covid-19 pandemic, people are always exposed to information about the dangers or threats of exposure to the virus, known as health risk messages. This study was conducted to explain how a number of individual characteristics in the health risk message information environment correlate to their attitudes towards the risk of exposing Covid-19. This online survey of people who have received the Covid-19 vaccine found that several variables related to lifestyle and disease history were correlated to perceptions of the risk of exposure to Covid-19. It also confirms that there is a positive correlation between awareness of the amount of risk an individual has and perceptions of the risk of exposing Covid-19.
Kadar 8-Oxo-7, 8-Dihydro-2’-Deoxyguanosine (8-Oxo-Dgsn) Dalam Urine Sebagai Biomarker Penuaan Pada Pasien Tb Paru
Authors: Wijaya Cathrine Meryani , Santoso Arif , Hamid Firdaus , As’ad Suryani , Bukhari Agussalim , Zainuddin Alfian
Published: January 2022

Proses penuaan merupakan proses fisiologis yang tidak dapat dihindari. Pengukuran 8-oxo-dGsn dalam urin berpotensi sebagai cara baru untuk mengevaluasi proses penuaan dalam menentukan dan memperkirakan usia fisiologis. Penelitian ini betujuan untuk mengetahui kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada pasien tuberculosis paru.  Penelitian ini menggunakan pendekatan case control yakni penderita TB paru sebagai kelompok kasus dan kelompok orang sehat sebagai control dengan jumlah sampel sebanyak 50 orang (25 orang kasus dan 25 orang kontrol). Data dianalisis dengan menggunakan SPSS 21.0 (SPSS, Inc. Chicago, IL) dengan tingkat kemaknaan α=0.05.Hasil penelitian menunjukkan bahwa Kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada kelompok kasus  rata-rata 3.21±0.88. Kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada kelompok kontrol rata-rata 2.38±0.71. Ada korelasi positif antara umur dengan kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan (p < 0,001), dimana semakin bertambah umur maka kadar 8-Hydroxy-deoxyguanosine (8-OHdG) semakin tinggi. Terdapat perbedaan yang bermakna (p:0.001) secara statistik kadar 8-Hydroxy-deoxyguanosine (8-OHdG) sebagai biomarker penuaan antara kelompok kasus dengan kelompok kontrol.  Kesimpulan penelitian ini adalah Tuberculosis paru mempercepat proses penuaan yang ditandai dengan peningkatan kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urine sebagai biomarker penuaan.
Analisis Bakteriologis Air Minum Isi Ulang di Kecamatan Ratolindo, Kabupaten Tojo Una-Una
Authors: Hasanah Hasanah , Pitriani Pitriani , Nurdin Nurdin
Published: January 2022

Salah satu indikator yang digunakan untuk air minum yang aman untuk kesehatan adalah bakteriologi. Air minum yang aman adalah air yang tidak mengandung Escherichia coli dan/atau total bakteri coliform. Sehingga adanya Escherichia coli dan/atau total bakteri coliform dalam air minum menunjukkan bahwa dalam air minum telah terkontaminasi cemaran bakteriologi. Tujuan dari penelitian ini untuk Menganalisis bakteriologis air minum isi ulang di Kecamatan Ratolindo, Kabupaten Tojo Una-Una. Penelitian ini bersifat deskriptif dengan pendekatan uji laboratorium, hasil disajikan dalam bentuk tabel dan narasi. Sampel air minum dalam penelitian ini diambil di 11 depot air minum isi ulang secara composite sampel by time. Hasil pemeriksaan kadar Escherichia coli pada sampel air minum isi ulang menunjukkan bahwa seluruh depot memenuhi syarat sedangkan pemeriksaan kadar total bakteri coliform terdapat 3 depot tidak memenuhi syarat kualitas air minum sesuai dengan permenkes no. 492/MENKES/PER/IV/2010. Hygiene sanitasi DAM dilihat dari aspek Tempat sebanyak 10 depot (90,9) memenuhi syarat dan 1 depot (9,1) tidak memenuhi syarat, aspek peralatan sebanyak 11depot (100) memenuhi syarat dan 0 depot (0) tidak memenuhi syarat, aspek penjamah sebanyak 4 depot (36,4) memenuhi syarat dan 7 depot (63,6) tidak memenuhi syarat, aspek air minum sebanyak 10 depot (90,90) memenuhi syarat dan 1 depot (9,10) tidak memenuhi syarat.
Impact of the government size on economic growth in the Western Balkan countries
Authors: Bajrami Roberta , Gashi Adelina , Ukshini Kosovare , Rexha Donat
Published: January 2022

The Keynesian theory states that economic growth is positively affected by government spending, while Classical theory states that economic growth is negatively affected by government spending, as is stated by neoclassical public choice theorists (Nyasha & Odhiambo, 2019). Based on these theories, many authors have carried out research on the impact of economic freedom on economic growth by analyzing various empirical cases. Bergh and Karlsson (2010) with the findings from his paper confirmed that the countries with the highest government size have an elevated growth in the globalization index of KOF and the Fraser Institute’s economic freedom index. The main aim of this paper is to analyze the government size impact on the growth of the economy in the Western Balkan in the time period 2000–2017 according to Fraser Institute’s data, incorporating the following econometric models: fixed and random effects, pooled ordinary least squares (OLS), and Hausman-Taylor IV. With these models, this paper analyzes a government size and its components: government enterprises and investment, government consumption, transfers, and subsidies. The results illustrate a relationship between the size of the government and the growth of the economy in the Western Balkans that is positive. 1% increase in government size affects 0.29% gross domestic product (GDP) growth per capita. According to the Hausman-Taylor instrumental variable, 1% growth of government consumption is affected by 0.69% the decline in GDP per capita. The growth rate of transfers and subsidies affects 0.17% of GDP growth per capita and 1% of government enterprises and investment affects 0.54% GDP growth per capita.
Rapp-Hodgkin Syndrome with palmoplantar keratoderma
Authors: abdelli wissal , Souissi Asmahene , Sassi Wiem , Alaoui Fatima , Mokni Mourad
Published: January 2022

Rapp-Hodgkin syndrome is a rare condition that is characterized by
ectodermal dysplasia and palatal abnormalities. We describe a
15-year-old male who has Rapp-Hodgkin syndrome that is associated with a
palmoplantar keratoderma.
Design of atypical facade architectural elements as noise reduction barriers - case study
Authors: Vasov Miomir , Sumarac-Pavlovic Dragana , Mijic Miomir , Randjelovic Dusan , Kostic Dragan
Published: January 2022

The presented work is the result of affirmation of synergistic work of
experts dealing with architectural and acoustic design with the aim and
purpose of finding an adequate solution for optimal correction of the effect
of GHG systems installed on the facade of the subject (case study) office
building in Belgrade. Measurements established that the noise of the
constructed GHG systems affected the residential building in the immediate
vicinity. The effect of the constructed devices (refers to the installed
units) of the office building in question in the case when they operate at
full capacity was measuring to be about 58 dB (A). The urban zone in which
the building is located (Vracar-Belgrade) belongs to the category of
"office residential area" in which the outdoor noise level permitted for the
period of day is 60 dB (A), and for the night period is 50 dB (A). Taking
into account the stated facts, it has been unequivocally established that
GHG systems to a certain extent exceed the permitted noise levels and
"endanger" the neighboring observed building. The subject of this
professional scientific research is the design of atypical facade
architectural elements as a barrier reducing noise on the example of an
office building in Belgrade. The architectural challenge was reflected in
the fact that, in addition to designing the facade element which, at the
request of the investor must not compromise the architecture of the
building, therefore, should be "atypical in architectural design", it must
also provide flexibility in applying different variants of acoustic
barriers, which in addition to architectonic requirement must provide an
adequate response to acoustic requirements. To the satisfaction of the
authors, the designed barrier confirmed a successful synergy solution. The
adopted architectural-acoustic configuration of the barrier proved to be
effective regardless of the type of installed air conditioners, which in
some way justifies the initial idea of strong causality of acoustic and
architectural design, as a synergistic principle.
Properties of steel-polypropilene hybrid fibers reinforced concrete
Authors: Ristic Nenad , Grdic Dusan , Bijeljic Jelena , Grdic Zoran , Toplicic-Curcic Gordana
Published: January 2022

This paper present the results of mechanical properties of hybrid reinforced
concrete made by adding polypropylene and steel fibers into concrete
mixture. For the testing purposes were used steel fibers with hooked ends
and monofilament polypropylene fibers. The total of 5 batches of concrete
were made: concrete with addition of steel fibers, polypropylene fibers and
their combination in amount of 0,5 % of the concrete volume. The test
results show that concretes made by adding of 0.4% steel and 0.1%
polypropylene fibers have better performance compared to other concretes.
Characterization of PTC effect in BaTiO3-ceramics as a special phase transition - fractal approach
Authors: Vosika Zoran , Mitic Vojislav , Paunovic Vesna , Manojlovic Jelena , Lazovic Goran
Published: January 2022

The applications of BaTiO3-ceramics are very important and constantly
increasing nowadays. In that sense, we analyzed some phenomena related to
intergranular effects. We used experimental data based on Murata powders and
processing technology. Our original contribution to Heywang-Jonker-Daniels
inter-granular capacity model is based on thermodynamic fractal analysis
applied on phase transition in ceramic structures. In this case, PTCR effect
has a diffuse first-order phase transition character in a modified Landau
theory-fractal approach. Its basic properties are considered. This is an
original contribution as a bridge between theoretical aspects of
BaTiO3-ceramics and experimental results.
Autoscalabile ditributed anti-spam SMTP system based on kubernetes
Authors: Gavrilovic Nadja , Ciric Vladimir
Published: January 2022

Due to the increasing amount of spam email traffic, email users are in
increasing danger, while email server resources are becoming overloaded.
Therefore, it is necessary to protect email users, but also to prevent SMTP
system overload during spam attacks. The aim of this paper is to design and
implement an autoscalable distributed anti-spam SMTP system based on a Proof
of work concept. The proposed solution extends SMTP protocol in order to
enable the evaluation of the client?s credibility using the Proof of work
algorithm. In order to prevent resource overload during spam attacks, the
anti-spam SMTP system is implemented in a distributed environment, as a
group of multiple anti-spam SMTP server instances. Kubernetes architecture
is used for system distribution, configured with the possibility of
autoscaling the number of antispam SMTP server instances depending on the
system load. The implemented system is evaluated during a distributed spam
attempt, simulated by a custom-made traffic generator tool. Various
performance tests are given: (1) The proposed system?s impact on client?s
behaviour and the overall amount of spam messages, (2) The performance of
the undistributed anti-spam SMTP server during spam attack, in terms of
resource load analysis (3) Autoscaling demonstration and evaluation of
proposed distributed system?s performance during a spam attack. It is shown
that the proposed solution has the possibility of reducing the amount of
spam traffic, while processing tens of thousands of simultaneous SMTP client
requests in a distributed environment.
Association Between Change in Accelerometer-Measured and Self-Reported Physical Activity and Cardiovascular Disease in the Look AHEAD Trial
Authors: Jakicic John M. , Berkowitz Robert I. , Bolin Paula , Bray George A. , Clark Jeanne M. , Coday Mace , Egan Caitlin , Evans Mary , Foreyt John P. , Fulton Janet E. , Greenway Frank L. , Gregg Edward W. , Hazuda Helen P. , Hill James O. , Horton Edward S. , Hubbard Van S. , Jeffery Robert W. , Johnson Karen C. , Johnson Ruby , Kahn Steven E. , Kure Anne , Lang Wei , Lewis Cora E. , Nathan David M. , Patricio Jennifer , Peters Anne , Pi-Sunyer Xavier , Pownall Henry , Rejeski W. Jack , Safford Monika , Stewart Kerry J. , Wadden Thomas A. , Walkup Michael P. , Wing Rena R. , Wyatt Holly
Published: January 2022

OBJECTIVE: To conduct post-hoc
secondary analysis examining the association between change in physical
activity (PA), measured with self-report and accelerometry, from baseline to 1
and 4 years and cardiovascular disease (CVD) outcomes in the Look AHEAD Trial.

RESEARCH DESIGN AND METHODS: Participants were adults with overweight/obesity
and type 2 diabetes with PA data at baseline and year 1 or 4 (n = 1,978). Participants
were randomized to diabetes support and education or intensive lifestyle
intervention. Measures included accelerometry-measured moderate-to-vigorous PA
(MVPA), self-reported PA, and composite (morbidity and mortality) CVD outcomes.

RESULTS: In pooled analyses of all participants, using Cox
proportional hazards models, each 100 MET-min/wk increase in accelerometry-measured
MVPA from baseline to 4 years was associated with decreased risk of the subsequent
primary composite outcome of CVD. Results were consistent for changes in total MVPA
[HR=0.97 (95% CI: 0.95, 0.99)] and MVPA accumulated in >10-minute
bouts [HR=0.95 (95% CI: 0.91, 0.98)], with a similar pattern for secondary CVD
outcomes. Change in accelerometry-measured MVPA at 1 year and self-reported
change in PA at 1 and 4 years were not associated with CVD outcomes.

CONCLUSIONS: Increased accelerometry-measured MVPA from
baseline to year 4 is associated with decreased risk of CVD outcomes. This
suggests the need for long-term engagement in MVPA to reduce the risk of CVD in
adults with overweight/obesity and type 2 diabetes.
Sensing pedestrian flows for real-time assessment of non-pharmaceutical policy interventions during the COVID-19 pandemic
Authors: Klingwort Jonas , De Broe Sofie Myriam Marcel Gabrielle , Brocker Sven Alexander
Published: January 2022

IntroductionTo combat and mitigate the transmission of the SARS-CoV-2 virus, reducing the number of social contacts within a population is highly effective. Non-pharmaceutical policy interventions, e.g. stay-at-home orders, closing schools, universities, and (non-essential) businesses, are expected to decrease pedestrian flows in public areas, leading to reduced social contacts. The extent to which such interventions show the targeted effect is often measured retrospectively by surveying behavioural changes. Approaches that use data generated through mobile phones are hindered by data confidentiality and privacy regulations and complicated by selection effects. Furthermore, access to such sensitive data is limited. However, a complex pandemic situation requires a fast evaluation of the effectiveness of the introduced interventions aiming to reduce social contacts. Location-based sensor systems installed in cities, providing objective measurements of spatial mobility in the form of pedestrian flows, are suited for such a purpose. These devices record changes in a population’s behaviour in real-time, do not have privacy problems as they do not identify persons, and have no selection problems due to ownership of a device.
ObjectiveThis work aimed to analyse location-based sensor measurements of pedestrian flows in 49 metropolitan areas at 100 locations in Germany to study whether such technology is suitable for the real-time assessment of behavioural changes during a phase of several different pandemic-related policy interventions.
MethodsSpatial mobility data of pedestrian flows was linked with policy interventions using the date as a unique linkage key. Data was visualised to observe potential changes in pedestrian flows before or after interventions. Furthermore, differences in time series of pedestrian counts between the pandemic and the pre-pandemic year were analysed.
ResultsThe sensors detected changes in mobility patterns even before policy interventions were enacted. Compared to the pre-pandemic year, pedestrian counts were 85% lower.
ConclusionsThe study illustrated the practical value of sensor-based real-time measurements when linked with non-pharmaceutical policy intervention data. This study’s core contribution is that the sensors detected behavioural changes before enacting or loosening non-pharmaceutical policy interventions. Therefore, such technologies should be considered in the future by policymakers for crisis management and policy evaluation.
Holocene Carbon Accumulation, Wetness Shifts and Fire History at Three Threatened Peatlands in Carmarthenshire, SW Wales, UK
Authors:   , Holder Kristy
Published: January 2022

This project studies three peatlands in Carmarthenshire, SW Wales, UK (Figyn Common, Pyllau Cochion and Mynydd Bach) that are threatened by the impacts of continued human interference and projected climate change. The threat that human and climatic forces pose on peatland carbon storage has become a significant global concern in the fight against greenhouse gas climate forcing. A record of their Holocene environmental and developmental history is obtained via a multi-proxy analysis, including carbon:nitrogen ratio (C:N), humification, charcoal and carbon accumulation. Potential drivers of developmental change and temporal carbon accumulation are also explored. Fen peat inception occurred at ca. 10800, ca. 9730 and ca. 7960 cal yrs. BP at Figyn Common, Pyllau Cochion and Mynydd Bach (respectively). The fen to bog transition (FBT) is dated to ca. 5120 cal yrs. BP at Pyllau Cochion and ca. 4480 cal yrs. BP at Figyn Common. The FBT does not take place at Mynydd Bach. Evidence of regional wet shifts during the late Holocene is found at ca. 2000 and ca. 850 cal yrs. BP and a dry shift is detected at ca. 2400 cal yrs. BP. All three sites demonstrate evidence of burning through the Mesolithic period and on-site burning increases at all sites after ca. 4500 cal yrs. BP. At Mynydd Bach, fire activity is linked to Bronze Age ritual practices. Long-term Apparent Rates of Carbon Accumulation (LARCA) for the three sites are 23.71, 13.09 and 42.55 g C m -2 yr -1 for Pyllau Cochion, Mynydd Bach, and Figyn Common (respectively). Carbon accumulation is high in the early Holocene, likely in response to the faster accumulation rates associated with early fen stages. However, in contrast to other northern peatlands carbon accumulation is lower during the Holocene Thermal Maximum and higher in the late Holocene when neoglacial cooling persisted. This is most likely because they sit close to the bioclimatic threshold of peatland formation in a UK context. Furthermore, an association between shorter-term wet shifts and higher carbon accumulation is found at several points in the Pyllau Cochion and Figyn Common record. The findings imply that the sites accumulate more carbon during wetter/cooler conditions and less when it is warmer/drier. Therefore, it is likely that they will experience reductions in carbon accumulation in response to projected warming during the 21st century. This adds support to the widely reported theory in the literature that peripheral peatlands will be the first to see losses in their carbon sequestration capacity because of predicted warming. This work contributes to the public understanding of the environmental history of these peatlands and the results provide valuable insight for conservation and future management strategies along with an assessment of carbon projections.
NUMBER SENSE DALAM MEMECAHKAN MASALAH MATEMATIKA PADA MAHASISWA IKIP PGRI PONTIANAK
Authors: Babaro Fellya , Risalah Dewi , Sandie Sandie
Published: January 2022

Number sense is a person towards numbers, number sense is needed for students in the process of learning mathematics. Students with good number sense will be able to use their knowledge of numbers in solving mathematical problems. Therefore, it is necessary to do about how students use their number sense skills in mathematical problem situations. This study aims to determine how the number sense of students in solving mathematical problems. This type of research is qualitative research. The method used is a descriptive method in the form of case study research. The subjects in this study were IKIP PGRI Pontianak students who came from the mathematics education study program which collected 8 people. The instruments used in this study were test questions and interviews. From the results of data analysis and subject representation in displaying number sense in each C1-C5 component, the researcher concluded that all subjects had good number sense, seen from all who had number sense with a percentage of more than 60%.
ANALISIS PELAKSANAAN E-TENDERING JASA KONSTRUKSI BERDASARKAN PRINSIP-PRINSIP PENGADAAN BARANG DAN JASA DI PERGURUAN TINGGI
Authors: Arifin Ari Syaiful Rahman
Published: January 2022

Penelitian ini bertujuan untuk menganalisis pelaksanaan E-Tendering jasa konstruksi berdasarkan prinsip-prinsip pengadaan barang dan jasa di perguruan tinggi, khususnya di Universitas Negeri Padang. Metoda penelitian yang digunakan adalah metoda deskriptif. Teknik pengumpulan data yang digunakan melalui observasi, wawancara, dokumen fisik tender dan data elektronik melalui aplikasi SPSE. Analisis data yang digunakan adalah analisis data kualitatif. Hasil penelitian menunjukkan bahwa proses pelaksanaan E-Tendering jasa konstruksi di perguruan tinggi, khususnya Universitas Negeri Padang sudah berjalan dengan baik sesuai dengan regulasi pengadaan barang dan jasa pemerintah berdasarkan prinsip-prinsip pengadaan barang dan jasa yaitu efisien, efektif, terbuka dan bersaing, transparan, adil atau tidak diskriminatif dan akuntabel. Untuk menjaga agar pelaksanaan proses E-Tendering jasa konstruksi selalu berpedoman kepada prinsip-prinsip pengadaan diharapkan selalu mengikuti dan menerapkan regulasi-regulasi terbaru serta menguasai aplikasi sistem E-Tendering jasa konstruksi terkini.