bluuebunny/crossref_metadata_2025 huggingface dataset:
Microfluidic Paper-Based Sample Concentration Using Ion Concentration Polarization with Smartphone Detection
Authors: Li Xue , Niu Yanan , Chen Yunyi , Wu Di , Yi Long , Qiu Xianbo
Published: November 2016

A simple method for microfluidic paper-based sample concentration using ion concentration polarization (ICP) with smartphone detection is developed. The concise and low-cost microfluidic paper-based ICP analytical device, which consists of a black backing layer, a nitrocellulose membrane, and two absorbent pads, is fabricated with the simple lamination method which is widely used for lateral flow strips. Sample concentration on the nitrocellulose membrane is monitored in real time by a smartphone whose camera is used to collect the fluorescence images from the ICP device. A custom image processing algorithm running on the smartphone is used to track the concentrated sample and obtain its fluorescence signal intensity for quantitative analysis. Two different methods for Nafion coating are evaluated and their performances are compared. The characteristics of the ICP analytical device especially with intentionally adjusted physical properties are fully evaluated to optimize its performance as well as to extend its potential applications. Experimental results show that significant concentration enhancement with fluorescence dye sample is obtained with the developed ICP device when a fast depletion of fluorescent dye is observed. The platform based on the simply laminated ICP device with smartphone detection is desired for point-of-care testing in settings with poor resources.
Mineralogy, Geochemistry and Fluid Inclusion Data from the Tumanpınarı Volcanic Rock-Hosted Fe-Mn-Ba Deposit, Balıkesir-Dursunbey, Turkey
Authors: Gultekin Ali , Balci Nurgul
Published: November 2016

The Tumanpınarı mineralization is a volcanic rock-hosted epithermal Fe-Mn-Ba deposit located in the southwestern part of Dursunbey, Balıkesir, Turkey. The deposit constitutes one of the most important deposits of the Havran-Dursunbey metallogenic sub-province in which numerous Early Miocene Fe-Mn-Ba deposits are distributed. The ore occurs as open-space fillings in faults, fractures, and breccias in the andesite. Early hydrothermal activity was responsible for four types of hypogene alteration in decreasing intensity: silicification, sericitization, hematization and argillic alteration. The mineral assemblage includes pyrolusite, psilomelane, hematite, and barite as well as minor magnetite, manganite, poliannite, limonite, braunite, bixbyite, galena, pyrite, and goethite. Mineralogically, three ore types are recognized as pyrolusite + psilomelane + hematite + barite ore, pyrolusite + psilomelane + poliannite ore and barite + pyrolusite + psilomelane + hematite ore (barite-dominant ore). In addition to Fe, Mn and Ba, the ore contains substantial quantities of Pb, Zn, As. Chemically, the transition from fresh to altered rocks has little effect on the elemental levels for Si, Al, Fe, Ca, Mg, K, Rb, Sr and H2O. The homogenization temperature of fluid inclusions hosted in the main stage quartz and barite ranged from 113 to 410 °C with salinities ranging from 0.4 to 14.9 eq. wt % NaCl, respectively. Overall, the available data suggest that the deposits formed as the result of the interaction of two aqueous fluids: a higher-salinity fluid (probably magmatic) and a dilute meteoric fluid.
Chemopreventive Agents and Inhibitors of Cancer Hallmarks: May Citrus Offer New Perspectives?
Authors: Cirmi Santa , Ferlazzo Nadia , Lombardo Giovanni , Maugeri Alessandro , Calapai Gioacchino , Gangemi Sebastiano , Navarra Michele
Published: November 2016

Fruits and vegetables have long been recognized as potentially important in the prevention of cancer risk. Thus, scientific interest in nutrition and cancer has grown over time, as shown by increasing number of experimental studies about the relationship between diet and cancer development. This review attempts to provide an insight into the anti-cancer effects of Citrus fruits, with a focus on their bioactive compounds, elucidating the main cellular and molecular mechanisms through which they may protect against cancer. Scientific literature was selected for this review with the aim of collecting the relevant experimental evidence for the anti-cancer effects of Citrus fruits and their flavonoids. The findings discussed in this review strongly support their potential as anti-cancer agents, and may represent a scientific basis to develop nutraceuticals, food supplements, or complementary and alternative drugs in a context of a multi-target pharmacological strategy in the oncology.
Assessment of Breast Milk Iodine Concentrations in Lactating Women in Western Australia
Authors: Jorgensen Anita , O’Leary Peter , James Ian , Skeaff Sheila , Sherriff Jillian
Published: November 2016

Breast-fed infants may depend solely on an adequate supply of iodine in breast milk for the synthesis of thyroid hormones which are essential for optimal growth and cognitive development. This is the first study to measure breast milk iodine concentration (BMIC) among lactating women in Western Australian (n = 55). Breast milk samples were collected between 2014 and 2015 at a mean (±SD) of 38.5 (±5.5) days post-partum. The samples were analysed to determine median BMIC and the percentage of samples with a BMIC < 100 µg/L, a level considered adequate for breast-fed infants. The influence of (a) iodine-containing supplements and iodised salt use and (b) consumption of key iodine-containing foods on BMIC was also examined. The median (p25, p75) BMIC was 167 (99, 248) µg/L and 26% of samples had a BMIC < 100 µg/L. Overall, BMIC tended to be higher with iodine-containing supplement usage (ratio 1.33, 95% confidence interval (CI) (1.04, 1.70), p = 0.030), cow’s milk consumption (ratio 1.66, 95% CI (1.23, 2.23), p = 0.002) and lower for Caucasians (ratio 0.61, 95% CI (0.45, 0.83), p = 0.002), and those with secondary school only education (ratio 0.66, 95% CI (0.46, 0.96), p = 0.030). For most women, BMIC was adequate to meet the iodine requirements of their breast-fed infants. However, some women may require the use of iodine-containing supplements or iodised salt to increase BMIC to adequate levels for optimal infant nutrition.
Reply to C. Ferreira-Pêgo’s Letter to the Editor Re: Nissensohn M. et al.; Nutrients 2016, 8, 232
Authors: Nissensohn Mariela , Serra-Majem Lluis
Published: November 2016

We would like to thank you for the opportunity to answer to the Letter to the Editor from Ferreira-Pêgo, Babio and Salas-Salvadó [1] regarding our recent publication entitled “Beverage Consumption Habits and Association with Total Water and Energy Intakes in the Spanish Population: Findings of the ANIBES Study” [2].[...]
Dietary Iodine Intake of the Australian Population after Introduction of a Mandatory Iodine Fortification Programme
Authors: Charlton Karen , Probst Yasmine , Kiene Gabriella
Published: November 2016

To address mild iodine deficiency in Australia, a mandatory fortification program of iodised salt in bread was implemented in 2009. This study aimed to determine factors associated with achieving an adequate dietary iodine intake in the Australian population post-fortification, and to assess whether bread consumption patterns affect iodine intake in high-risk groups. Using nationally representative data of repeated 24-h dietary recalls from the 2011–2012 Australian National Nutrition and Physical Activity Survey, dietary iodine intakes and food group contributions were compared by age, socioeconomic status (SES), and geographical remoteness (N = 7735). The association between fortified bread intake and adequacy of iodine intake (meeting age and sex-specific Estimated Average Requirements) was investigated using logistic regression models in women of childbearing age 14–50 years (n = 3496) and children aged 2–18 years (n = 1772). The effect of SES on bread consumption was further investigated in a sub group of children aged 5–9 years (n = 488). Main sources of iodine intake at the time of the survey were cereal and cereal products, followed by milk products and dishes. Differences in iodine intake and dietary iodine habits according to age, SES and location were found (p < 0.001) for women of child-bearing age. Fortified bread consumption at ≥100 g/day was associated with five times greater odds of achieving an adequate iodine intake (OR 5.0, 95% CI 4.96–5.13; p < 0.001) compared to lower bread consumption in women and 12 times in children (OR 12.34, 95% CI 1.71–89.26; p < 0.001). Disparities in dietary iodine intake exist within sectors of the Australian population, even after mandatory fortification of a staple food. On-going monitoring and surveillance of iodine status is required.
Electronic Waste and Existing Processing Routes: A Canadian Perspective
Authors: Kumar Amit , Holuszko Maria
Published: November 2016

Electrical and electronic products have become an integral part of the current economy and, with the development of newer technologies, the life span of these products are getting shorter. As a consequence, the volume of electronic waste is increasing drastically around the globe. With the implementation of new rules, regulations, and policies by the government, the landfilling of electronic waste has been reduced. The presence of valuable metals in the e-waste stream provides a major economic benefit for recycling industries but, due to the presence of hazardous materials, a proper recycling technique is required prior to the disposal of the e-waste. The total e-waste generated in Canada was 725 kt in 2014. There are several organizations currently working in various provinces to deal with the collection and recycling of e-waste. These organizations collected nearly 20% of the total e-waste generated in 2014. The collection rate for e-waste can be boosted by increasing awareness and by creating more centers to collect all kinds of e-waste. The collected e-waste is processed at local processing facilities mostly dealing with dismantling and hazardous material removal processes and then shipping the remaining material to a central location for subsequent processing.
Impacts of Temporal-Spatial Variant Background Ionosphere on Repeat-Track GEO D-InSAR System
Authors: Hu Cheng , Li Yuanhao , Dong Xichao , Cui Chang , Long Teng
Published: November 2016

An L band geosynchronous synthetic aperture radar (GEO SAR) differential interferometry system (D-InSAR) will be obviously impacted by the background ionosphere, which will give rise to relative image shifts and decorrelations of the SAR interferometry (InSAR) pair, and induce the interferometric phase screen errors in interferograms. However, the background ionosphere varies within the long integration time (hundreds to thousands of seconds) and the extensive imaging scene (1000 km levels) of GEO SAR. As a result, the conventional temporal-spatial invariant background ionosphere model (i.e., frozen model) used in Low Earth Orbit (LEO) SAR is no longer valid. To address the issue, we firstly construct a temporal-spatial background ionosphere variation model, and then theoretically analyze its impacts, including relative image shifts and the decorrelation of the GEO InSAR pair, and the interferometric phase screen errors, on the repeat-track GEO D-InSAR processing. The related impacts highly depend on the background ionosphere parameters (constant total electron content (TEC) component, and the temporal first-order and the temporal second-order derivatives of TEC with respect to the azimuth time), signal bandwidth, and integration time. Finally, the background ionosphere data at Isla Guadalupe Island (29.02°N, 118.27°W) on 7–8 October 2013 is employed for validating the aforementioned analysis. Under the selected background ionosphere dataset, the temporal-spatial background ionosphere variation can give rise to a relative azimuth shift of dozens of meters at most, and even the complete decorrelation in the InSAR pair. Moreover, the produced interferometric phase screen error corresponds to a deformation measurement error of more than 0.2 m at most, even in a not severely impacted area.
Trying to Break New Ground in Aerial Archaeology
Authors: Verhoeven Geert , Sevara Christopher
Published: November 2016

Aerial reconnaissance continues to be a vital tool for landscape-oriented archaeological research. Although a variety of remote sensing platforms operate within the earth’s atmosphere, the majority of aerial archaeological information is still derived from oblique photographs collected during observer-directed reconnaissance flights, a prospection approach which has dominated archaeological aerial survey for the past century. The resulting highly biased imagery is generally catalogued in sub-optimal (spatial) databases, if at all, after which a small selection of images is orthorectified and interpreted. For decades, this has been the standard approach. Although many innovations, including digital cameras, inertial units, photogrammetry and computer vision algorithms, geographic(al) information systems and computing power have emerged, their potential has not yet been fully exploited in order to re-invent and highly optimise this crucial branch of landscape archaeology. The authors argue that a fundamental change is needed to transform the way aerial archaeologists approach data acquisition and image processing. By addressing the very core concepts of geographically biased aerial archaeological photographs and proposing new imaging technologies, data handling methods and processing procedures, this paper gives a personal opinion on how the methodological components of aerial archaeology, and specifically aerial archaeological photography, should evolve during the next decade if developing a more reliable record of our past is to be our central aim. In this paper, a possible practical solution is illustrated by outlining a turnkey aerial prospection system for total coverage survey together with a semi-automated back-end pipeline that takes care of photograph correction and image enhancement as well as the management and interpretative mapping of the resulting data products. In this way, the proposed system addresses one of many bias issues in archaeological research: the bias we impart to the visual record as a result of selective coverage. While the total coverage approach outlined here may not altogether eliminate survey bias, it can vastly increase the amount of useful information captured during a single reconnaissance flight while mitigating the discriminating effects of observer-based, on-the-fly target selection. Furthermore, the information contained in this paper should make it clear that with current technology it is feasible to do so. This can radically alter the basis for aerial prospection and move landscape archaeology forward, beyond the inherently biased patterns that are currently created by airborne archaeological prospection.
An Improved Forwarding of Diverse Events with Mobile Sinks in Underwater Wireless Sensor Networks
Authors: Raza Waseem , Arshad Farzana , Ahmed Imran , Abdul Wadood , Ghouzali Sanaa , Niaz Iftikhar , Javaid Nadeem
Published: November 2016

In this paper, a novel routing strategy to cater the energy consumption and delay sensitivity issues in deep underwater wireless sensor networks is proposed. This strategy is named as ESDR: Event Segregation based Delay sensitive Routing. In this strategy sensed events are segregated on the basis of their criticality and, are forwarded to their respective destinations based on forwarding functions. These functions depend on different routing metrics like: Signal Quality Index, Localization free Signal to Noise Ratio, Energy Cost Function and Depth Dependent Function. The problem of incomparable values of previously defined forwarding functions causes uneven delays in forwarding process. Hence forwarding functions are redefined to ensure their comparable values in different depth regions. Packet forwarding strategy is based on the event segregation approach which forwards one third of the generated events (delay sensitive) to surface sinks and two third events (normal events) are forwarded to mobile sinks. Motion of mobile sinks is influenced by the relative distribution of normal nodes. We have also incorporated two different mobility patterns named as; adaptive mobility and uniform mobility for mobile sinks. The later one is implemented for collecting the packets generated by the normal nodes. These improvements ensure optimum holding time, uniform delay and in-time reporting of delay sensitive events. This scheme is compared with the existing ones and outperforms the existing schemes in terms of network lifetime, delay and throughput.
Improvement of Toluene-Sensing Performance of SnO2 Nanofibers by Pt Functionalization
Authors: Kim Jae-Hun , Abideen Zain , Zheng Yifang , Kim Sang
Published: November 2016

Functionalization of metal nanoparticles (NPs) on oxide materials is a commonly employed technique for enhancing the sensitivity and selectivity of materials for gas sensing applications. In this study, we functionalized electrospinning-synthesized SnO2 nanofibers (NFs) with various amounts of Pt NPs to enhance the toluene-sensing properties. In particular, Pt NPs were prepared by deposition of Pt films by sputtering and subsequent heat treatment. Electronic and chemical sensitizations by the Pt NPs were responsible for the improved toluene sensitivity. The best sensing properties were achieved at an optimized amount of Pt NPs, showing a volcano shape in relation to the amount of Pt NPs. The method used in this study is useful for the development of toluene-sensitive and -selective chemiresistive NF-based gas sensors.
Structure-Based Design of Novel Tetrahydro-Beta-Carboline Derivatives with a Hydrophilic Side Chain as Potential Phosphodiesterase Inhibitors
Authors: Elhady Ahmed , Sigler Sara , Noureldin Nazih , Canzoneri Joshua , Ahmed Nermin , Piazza Gary , Abadi Ashraf
Published: November 2016

Tadalafil is a clinically approved phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction and pulmonary arterial hypertension. It contains two chiral carbons, and the marketed isomer is the 6R, 12aR isomer with a methyl substituent on the terminal nitrogen of the piperazinedione ring. In this report, tadalafil analogues with an extended hydrophilic side chain on the piperazine nitrogen were designed to interact with particular hydrophilic residues in the binding pocket. This leads to analogues with moderate inhibitory activity on phosphodiesterase-5, even for isomers in which chiral carbons are of the S configuration.
Anomalous Separation of Small Y-Chromosomal DNA Fragments on Microchip Electrophoresis
Authors: Jabasini Mohammad , Ewis Ashraf , Sato Youichi , Nakahori Yutaka , Baba Yoshinobu
Published: November 2016

We investigated an anomalous DNA separation where two DNA fragments from the human Y-chromosome sY638 (64 bp) and sY592 (65 bp), with only one base pair difference, were separated. This result is abnormal since in a previous study, we found that 5 bp was the minimum difference between two DNA fragments that the microchip electrophoresis system can separate. The formation of a mini-loop in the structure of the DNA fragment of sY638 (64 bp) was strongly expected to be the reason. To investigate this, we synthesized three modified DNA fragments for sY638 (64 bp), and the modifications were in two expected locations for possible mini-loop formation. Later, the separation between sY592 (65 bp) and the three modified fragments of sY638 (64 bp) was not possible. Thus, we conclude that the formation of a mini-loop in the structure of the DNA is the reason behind this anomalous separation.
Suitability of Root and Rhizome Anatomy for Taxonomic Classification and Reconstruction of Phylogenetic Relationships in the Tribes Cardueae and Cichorieae (Asteraceae)
Authors: Ginko Elisabeth , Dobeš Christoph , Saukel Johannes
Published: November 2016

The value of root and rhizome anatomy for the taxonomic characterisation of 59 species classified into 34 genera and 12 subtribes from the Asteraceae tribes Cardueae and Cichorieae was assessed. In addition, the evolutionary history of anatomical characters was reconstructed using a nuclear ribosomal DNA sequence-based phylogeny of the Cichorieae. Taxa were selected with a focus on pharmaceutically relevant species. A binary decision tree was constructed and discriminant function analyses were performed to extract taxonomically relevant anatomical characters and to infer the separability of infratribal taxa, respectively. The binary decision tree distinguished 33 species and two subspecies, but only five of the genera (sampled for at least two species) by a unique combination of hierarchically arranged characters. Accessions were discriminated—except for one sample worthy of discussion—according to their subtribal affiliation in the discriminant function analyses (DFA). However, constantly expressed subtribe-specific characters were almost missing and even in combination, did not discriminate the subtribes. Most anatomical characters showed at least some degree of homoplasious evolution limiting their suitability as phylogenetically informative characters.
Chitosan-Montmorillonite Polymer Composites: Formulation and Evaluation of Sustained Release Tablets of Aceclofenac
Authors: Thakur Garima , Singh Amrinder , Singh Inderbir
Published: November 2016

The present study reports the preparation and evaluation of polymer composites of chitosan and montmorillonite. The prepared polymer composites were evaluated for various powder properties and characterized by FTIR-ATR (Fourier Transform Infrared Spectroscopy- Attenuated Total Reﬂectance), XRD (X Ray Diffraction), and SEM (Scaning Electron Microscopy) techniques. Heckel and Kawakita equations indicated good compression characteristics of the composites. The polymer composites were employed in formulating sustained release tablets of aceclofenac. The formation of intercalated lamellar structures due to the entrapment of clay particles in the polymeric matrix network was found to be responsible for the drug release retardant behavior of the composites. The in vitro drug release data were ﬁtted to various models like zero-order, ﬁrst-order, Higuchi, Korsmeyer-Peppas, and Hixon and Crowell for studying the mechanism of drug release from the formulation. The value of release exponent (n) was found to range between 0.59 and 0.82, indicating non-Fickian (anomalous) drug release behavior. Swelling-induced diffusion of the drug through the polymer matrix and polymer matrix chain relaxation appeared to play a role in the release of the drug from the polymer composites.
Effect of Cyclodextrin Types and Co-Solvent on Solubility of a Poorly Water Soluble Drug
Authors: Charumanee Suporn , Okonogi Siriporn , Sirithunyalug Jakkapan , Wolschann Peter , Viernstein Helmut
Published: November 2016

The aim of the study was to investigate the solubility of piroxicam (Prx) depending on the inclusion complexation with various cyclodextrins (CDs) and on ethanol as a co-solvent. The phase-solubility method was applied to determine drug solubility in binary and ternary systems. The results showed that in systems consisting of the drug dissolved in ethanol–water mixtures, the drug solubility increased exponentially with a rising concentration of ethanol. The phase solubility measurements of the drug in aqueous solutions of CDs, β-CD and γ-CD exhibited diagrams of AL-type, whereas 2,6-dimethyl-β-CD revealed AP-type. The destabilizing effect of ethanol as a co-solvent was observed for all complexes regardless of the CD type, as a consequence of it the lowering of the complex formation constants. In systems with a higher concentration of ethanol, the drug solubility was increased in opposition to the decreasing complex formation constants. According to this study, the type of CDs played a more important role on the solubility of Prx, and the use of ethanol as a co-solvent exhibited no synergistic effect on the improvement of Prx solubility. The Prx solubility was increased again due to the better solubility in ethanol.
Development of Social Intensity Database Using Asian International Input–Output Table for Social Life Cycle Assessment
Authors: Papong Seksan , Itsubo Norihiro , Ono Yuya , Malakul Pomthong
Published: November 2016

The social impacts of products and service life cycles are increasingly of interest among policy makers and stakeholders. Workers’ issues are considered to be a source of key inventory data to assess social impacts, and are crucial in moving towards social sustainability. There is a need to develop a social inventory database for evaluating social impacts of products and services. This study aimed at the development of a social intensity dataset using an input–output analysis framework. The 2005 Asian International input–output table is used in this work. Six social issues are considered: total employment, paid workers, vulnerable employment, wages, fatal, and non-fatal occupational injuries. To verify the acceptability of this study, an estimation of total social footprint deduced from final consumption rates was carried out. The social intensities associated with 10 countries and 76 economic sectors were constructed. The results show that the social intensities from cradle to gate the agricultural sector has the highest in terms of total employment and vulnerable employment. Meanwhile, the mining sector in China has a higher non-fatal and fatal occupational injuries than the agriculture sector, secondary sector, and tertiary sector. The public administration sector and the education and research sector had a higher wages intensity than any other sectors due to these sectors being labor intensive and having higher wages. The social intensity in terms of total employment, paid workers, vulnerable employment, non-fatal injuries, and fatal accident cases in the developing countries was higher than the developed countries whereas wages intensity in developing countries was lower than that of developed countries. The social footprints resulting from the final consumption of each country show that the social footprints had transferred from the developing countries to the developed countries. Exports from China to the USA, Japan, South Korea, Taiwan, and Singapore have a significant social impact in these countries.
RSSI-Based Distance Estimation Framework Using a Kalman Filter for Sustainable Indoor Computing Environments
Authors: Sung Yunsick
Published: November 2016

Given that location information is the key to providing a variety of services in sustainable indoor computing environments, it is required to obtain accurate locations. Locations can be estimated by three distances from three fixed points. Therefore, if the distance between two points can be measured or estimated accurately, the location in indoor environments can be estimated. To increase the accuracy of the measured distance, noise filtering, signal revision, and distance estimation processes are generally performed. This paper proposes a novel framework for estimating the distance between a beacon and an access point (AP) in a sustainable indoor computing environment. Diverse types of received strength signal indications (RSSIs) are used for WiFi, Bluetooth, and radio signals, and the proposed distance estimation framework is unique in that it is independent of the specific wireless signal involved, being based on the Bluetooth signal of the beacon. Generally, RSSI measurement, noise filtering, and revision are required for distance estimation using RSSIs. The employed RSSIs are first measured from an AP, with multiple APs sometimes used to increase the accuracy of the distance estimation. Owing to the inevitable presence of noise in the measured RSSIs, the application of noise filtering is essential, and further revision is used to address the inaccuracy and instability that characterizes RSSIs measured in an indoor environment. The revised RSSIs are then used to estimate the distance. The proposed distance estimation framework uses one AP to measure the RSSIs, a Kalman filter to eliminate noise, and a log-distance path loss model to revise the measured RSSIs. In the experimental implementation of the framework, both a RSSI filter and a Kalman filter were respectively used for noise elimination to comparatively evaluate the performance of the latter for the specific application. The Kalman filter was found to reduce the accumulated errors by 8% relative to the RSSI filter. This confirmed the accuracy of the proposed distance estimation framework.
Uncertain Quality Function Deployment Using a Hybrid Group Decision Making Model
Authors: Wang Ze-Ling , You Jian-Xin , Liu Hu-Chen
Published: November 2016

Quality function deployment (QFD) is a widely used quality system tool for translating customer requirements (CRs) into the engineering design requirements (DRs) of products or services. The conventional QFD analysis, however, has been criticized as having some limitations such as in the assessment of relationships between CRs and DRs, the determination of CR weights and the prioritization of DRs. This paper aims to develop a new hybrid group decision-making model based on hesitant 2-tuple linguistic term sets and an extended QUALIFLEX (qualitative flexible multiple criteria method) approach for handling QFD problems with incomplete weight information. First, hesitant linguistic term sets are combined with interval 2-tuple linguistic variables to express various uncertainties in the assessment information of QFD team members. Borrowing the idea of grey relational analysis (GRA), a multiple objective optimization model is constructed to determine the relative weights of CRs. Then, an extended QUALIFLEX approach with an inclusion comparison method is suggested to determine the ranking of the DRs identified in QFD. Finally, an analysis of a market segment selection problem is conducted to demonstrate and validate the proposed QFD approach.
Recombinant Marek’s Disease Virus as a Vector-Based Vaccine against Avian Leukosis Virus Subgroup J in Chicken
Authors: Liu Yongzhen , Li Kai , Gao Yulong , Gao Li , Zhong Li , Zhang Yao , Liu Changjun , Zhang Yanping , Wang Xiaomei
Published: November 2016

Avian leukosis virus subgroup J (ALV-J) is an immunosuppressive virus that causes considerable economic losses to the chicken industry in China. However, there is currently no effective vaccine to prevent ALV-J infection. In order to reduce the losses caused by ALV-J, we constructed two effective ALV-J vaccines by inserting the ALV-J (strain JL093-1) env or gag+env genes into the US2 gene of the Marek’s disease herpesviruses (MDV) by transfection of overlapping fosmid DNAs, creating two recombinant MDVs, rMDV/ALV-gag+env and rMDV/ALV-env. Analysis of cultured chicken embryo fibroblasts infected with the rMDVs revealed that Env and Gag were successfully expressed and that there was no difference in growth kinetics in cells infected with rMDVs compared with that of cells infected with the parent MDV. Chickens vaccinated with either rMDV revealed that positive serum antibodies were induced. Both rMDVs also effectively reduced the rate of positive viremia in chicken flocks challenged with ALV-J. The protective effect provided by rMDV/ALV-env inoculation was slightly stronger than that provided by rMDV/ALV-gag+env. This represents the first study where a potential rMDV vaccine, expressing ALV-J antigenic genes, has been shown to be effective in the prevention of ALV-J. Our study also opens new avenues for the control of MDV and ALV-J co-infection.
Spatio-Temporal Analysis of Water Quality Parameters in Machángara River with Nonuniform Interpolation Methods
Authors: Vizcaíno Iván , Carrera Enrique , Sanromán-Junquera Margarita , Muñoz-Romero Sergio , Luis Rojo-Álvarez José , Cumbal Luis
Published: November 2016

Water quality measurements in rivers are usually performed at intervals of days or months in monitoring campaigns, but little attention has been paid to the spatial and temporal dynamics of those measurements. In this work, we propose scrutinizing the scope and limitations of state-of-the-art interpolation methods aiming to estimate the spatio-temporal dynamics (in terms of trends and structures) of relevant variables for water quality analysis usually taken in rivers. We used a database with several water quality measurements from the Machángara River between 2002 and 2007 provided by the Metropolitan Water Company of Quito, Ecuador. This database included flow rate, temperature, dissolved oxygen, and chemical oxygen demand, among other variables. For visualization purposes, the absence of measurements at intermediate points in an irregular spatio-temporal sampling grid was fixed by using deterministic and stochastic interpolation methods, namely, Delaunay and k-Nearest Neighbors (kNN). For data-driven model diagnosis, a study on model residuals was performed comparing the quality of both kinds of approaches. For most variables, a value of k = 15 yielded a reasonable fitting when Mahalanobis distance was used, and water quality variables were better estimated when using the kNN method. The use of kNN provided the best estimation capabilities in the presence of atypical samples in the spatio-temporal dynamics in terms of leave-one-out absolute error, and it was better for variables with slow-changing dynamics, though its performance degraded for variables with fast-changing dynamics. The proposed spatio-temporal analysis of water quality measurements provides relevant and useful information, hence complementing and extending the classical statistical analysis in this field, and our results encourage the search for new methods overcoming the limitations of the analyzed traditional interpolators.
Harmonious Development between Socio-Economy and River-Lake Water Systems in Xiangyang City, China
Authors: Zuo Qiting , Luo Zengliang , Ding Xiangyi
Published: November 2016

River-lake water systems (RLS) are important carriers for matter transformation and energy transmission. Influenced by accelerated social and economic development, the structural, functional, and environmental states of RLS have been seriously damaged. It is an important problem for human beings to coordinate the contradiction between socio-economic development and the protection of RLS. In order to quantitatively study the harmonious relationship between socio-economic development and the state of RLS, the harmony theory method was used to analyze the degree of harmonious development between socio-economy and RLS in this study taking Xiangyang City as an example, and formulating corresponding harmonious optimization schemes. The results indicate that: (1) the state of RLS had a relatively small change during 2009–2014, and its spatial distribution shows a decreasing trend with the Han River as the central axis decreases on both of its sides; (2) before 2011, the driving force of socio-economic development in Xiang yang City mainly originated in the peripheral regions such as Laohekou City, Zaoyang City, and Gucheng County, but after 2011, it migrated rapidly towards Downtown, and reached the maximum in 2014; (3) when the influence of regional socio-economic development on RLS is small, socio-economic development is the main factor driving the change of the overall harmonious development degree of socio-economy and RLS. However when the influence is big, it is combined, driven by socio-economic development and the state of RLS; (4) the main factors affecting the overall harmonious degree of socio-economy and RLS in Xiangyang City include: river length, standard ratio of water quality, water consumption per capita, reservoir regulation capability, farmland irrigation water consumption per Mu (Mu is an area unit in China, 1 Mu approximately equals to 666.67 m2), and sewage treatment rate. This study can provide a reference for the future analysis of the harmonious development between socio-economy and RLS, as well as in formulating corresponding harmonious optimization schemes in China and other countries in a similar situation.
Learning for Transformation of Water Governance: Reflections on Design from the Climate Change Adaptation and Water Governance (CADWAGO) Project
Authors: Blackmore Chris , Van Bommel Severine , De Bruin Annemarieke , De Vries Jasper , Westberg Lotten , Powell Neil , Foster Natalie , Collins Kevin , Roggero Pier , Seddaiu Giovanna
Published: November 2016

This paper considers how learning for transformation of water governance in the context of climate change adaptation can be designed for and supported, drawing examples from the international climate change adaptation and water governance project (CADWAGO). The project explicitly set out to design for governance learning in the sense of developing elements of social infrastructure such as workshops, performances and online media to bring stakeholders together and to facilitate co-learning of relevance to governance. CADWAGO drew on a variety of international cases from past and ongoing work of the project partners. It created a forum for dialogue among actors from different contexts working at different levels and scales. The range of opportunities and constraints encountered are discussed, including the principles and practicalities of working with distributed processes of design and leadership of events. A range of concepts, tools and techniques were used to consider and facilitate individual and collective learning processes and outcomes associated with water governance in the context of climate adaptation. Questions were addressed about how elements of past, present and future water governance thinking and practice are connected and how multi-level systemic change in governance can take place. Some reflections on the effectiveness of the design for learning process are included. The nature of the contribution that projects such as CADWAGO can make in learning for transformation of water governance practices is also critically considered.
A New Rapid Simplified Model for Urban Rainstorm Inundation with Low Data Requirements
Authors: Shen Ji , Tong Zhong , Zhu Jianfeng , Liu Xiaofei , Yan Fei
Published: November 2016

This paper proposes a new rapid simplified inundation model (NRSIM) for flood inundation caused by rainstorms in an urban setting that can simulate the urban rainstorm inundation extent and depth in a data-scarce area. Drainage basins delineated from a floodplain map according to the distribution of the inundation sources serve as the calculation cells of NRSIM. To reduce data requirements and computational costs of the model, the internal topography of each calculation cell is simplified to a circular cone, and a mass conservation equation based on a volume spreading algorithm is established to simulate the interior water filling process. Moreover, an improved D8 algorithm is outlined for the simulation of water spilling between different cells. The performance of NRSIM is evaluated by comparing the simulated results with those from a traditional rapid flood spreading model (TRFSM) for various resolutions of digital elevation model (DEM) data. The results are as follows: (1) given high-resolution DEM data input, the TRFSM model has better performance in terms of precision than NRSIM; (2) the results from TRFSM are seriously affected by the decrease in DEM data resolution, whereas those from NRSIM are not; and (3) NRSIM always requires less computational time than TRFSM. Apparently, compared with the complex hydrodynamic or traditional rapid flood spreading model, NRSIM has much better applicability and cost-efficiency in real-time urban inundation forecasting for data-sparse areas.
Influence of hydrothermal synthesis parameters on the properties of hydroxyapatite nanoparticles
Authors: Kuśnieruk Sylwia , Wojnarowicz Jacek , Chodara Agnieszka , Chudoba Tadeusz , Gierlotka Stanislaw , Lojkowski Witold
Published: November 2016

Hydroxyapatite (HAp) nanoparticles of tunable diameter were obtained by the precipitation method at room temperature and by microwave hydrothermal synthesis (MHS). The following parameters of the obtained nanostructured HAp were determined: pycnometric density, specific surface area, phase purity, lattice parameters, particle size, particle size distribution, water content, and structure. HAp nanoparticle morphology and structure were determined using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). X-ray diffraction measurements confirmed crystalline HAp was synthesized, which was pure in terms of phase. It was shown that by changing the synthesis parameters, the diameter of HAp nanoparticles could be controlled. The average diameter of the HAp nanoparticles was determined by Scherrer’s equation via the Nanopowder XRD Processor Demo web application, which interprets the results of specific surface area and TEM measurements using the dark-field technique. The obtained nanoparticles with average particle diameter ranging from 8–39 nm were characterized by having homogeneous morphology with a needle shape and a narrow particle size distribution. Strong similarities were found when comparing the properties of some types of nanostructured hydroxyapatite with natural occurring apatite found in animal bones and teeth.
LOW-FREQUENCY RADIO OBSERVATIONS OF THE SOLAR CORONA WITH ARCMINUTE ANGULAR RESOLUTION: IMPLICATIONS FOR CORONAL TURBULENCE AND WEAK ENERGY RELEASES
Authors: Mugundhan V. , Ramesh R. , Barve Indrajit V. , Kathiravan C. , Gireesh G. V. S. , Kharb P. , Misra Apurva
Published: November 2016

We report on the first long baseline interferometer (length ≈8 km) observations of the solar corona at 37 MHz that were carried out recently with an angular resolution of

. The results indicate that, (1) discrete radio sources of the aforesaid angular size or even lesser are present in the solar corona from where radiation at the above frequency originates. This constrains the angular broadening of radio sources at low frequencies due to scattering by density turbulence in the solar corona; and (2) the observed sources in the present case correspond to the weakest energy releases in the solar atmosphere reported so far.
WHAT IS THE SOURCE OF QUIET SUN TRANSITION REGION EMISSION?
Authors: Schmit D. J. , De Pontieu Bart
Published: November 2016

Dating back to the first observations of the on-disk corona, there has been a qualitative link between the photosphere’s magnetic network and enhanced transition-temperature plasma emission. These observations led to the development of a general model that describes emission structures through the partitioning of the atmospheric volume with different magnetic loop geometries that exhibit different energetic equilibria. Does the internetwork produce transition-temperature emission? What fraction of network flux connects to the corona? How does quiet Sun emission compare with low-activity Sun-like stars? In this work, we revisit the canonical model of the quiet Sun, with high-resolution observations from the Interface Region Imaging Spectrograph (IRIS) and HMI in hand, to address those questions. We use over 900 deep exposures of Si iv 1393 Å from IRIS along with nearly simultaneous HMI magnetograms to quantify the correlation between transition-temperature emission structures and magnetic field concentrations through a number of novel statistics. Our observational results are coupled with analysis of the Bifrost MHD model and a large-scale potential field model. Our results paint a complex portrait of the quiet Sun. We measure an emission signature in the distant internetwork that cannot be attributed to network contribution. We find that the dimmest regions of emission are not linked to the local vertical magnetic field. Using the MHD simulation, we categorize the emission contribution from cool mid-altitude loops and high-altitude coronal loops and discuss the potential emission contribution of spicules. Our results provide new constraints on the coupled solar atmosphere so that we can build on our understanding of how dynamic thermal and magnetic structures generate the observed phenomena in the transition region.
A UNIFIED MODEL OF GRAIN ALIGNMENT: RADIATIVE ALIGNMENT OF INTERSTELLAR GRAINS WITH MAGNETIC INCLUSIONS
Authors: Hoang Thiem , Lazarian A.
Published: November 2016

The radiative torque (RAT) alignment of interstellar grains with ordinary paramagnetic susceptibilities has been supported by earlier studies. The alignment of such grains depends on the so-called RAT parameter q
max, which is determined by the grain shape. In this paper, we elaborate on our model of RAT alignment for grains with enhanced magnetic susceptibility due to iron inclusions, such that RAT alignment is magnetically enhanced, which we term the MRAT mechanism. Such grains can be aligned with high angular momentum at the so-called high-J attractor points, achieving a high degree of alignment. Using our analytical model of RATs, we derive the critical value of the magnetic relaxation parameter δ
m to produce high-J attractor points as functions of q
max and the anisotropic radiation angle relative to the magnetic field ψ. We find that if about 10% of the total iron abundance present in silicate grains is forming iron clusters, this is sufficient to produce high-J attractor points for all reasonable values of q
max. To calculate the degree of grain alignment, we carry out numerical simulations of MRAT alignment by including stochastic excitations from gas collisions and magnetic fluctuations. We show that large grains can achieve perfect alignment when the high-J attractor point is present, regardless of the values of q
max. Our obtained results pave the way for  the physical modeling of polarized thermal dust emission as well as magnetic dipole emission. We also find that millimeter-sized grains in accretion disks may be aligned with the magnetic field if they are incorporated with iron nanoparticles.
PONDEROMOTIVE ACCELERATION IN CORONAL LOOPS
Authors: Dahlburg R. B. , Laming J. M. , Taylor B. D. , Obenschain K.
Published: November 2016

Ponderomotive acceleration has been asserted to be a cause of the first ionization potential (FIP) effect, the well-known enhancement in abundance by a factor of 3–4 over photospheric values of elements in the solar corona with FIP less than about 10 eV. It is shown here by means of numerical simulations that ponderomotive acceleration occurs in solar coronal loops, with the appropriate magnitude and direction, as a “by-product” of coronal heating. The numerical simulations are performed with the HYPERION code, which solves the fully compressible three-dimensional magnetohydrodynamic equations including nonlinear thermal conduction and optically thin radiation. Numerical simulations of coronal loops with an axial magnetic field from 0.005 to 0.02 T and lengths from 25,000 to 75,000 km are presented. In the simulations the footpoints of the axial loop magnetic field are convected by random, large-scale motions. There is a continuous formation and dissipation of field-aligned current sheets, which act to heat the loop. As a consequence of coronal magnetic reconnection, small-scale, high-speed jets form. The familiar vortex quadrupoles form at reconnection sites. Between the magnetic footpoints and the corona the reconnection flow merges with the boundary flow. It is in this region that the ponderomotive acceleration occurs. Mirroring the character of the coronal reconnection, the ponderomotive acceleration is also found to be intermittent.