bluuebunny/crossref_metadata_2025 huggingface dataset:
Search for the True Nature of Nucleus-Nucleus Potentials
Authors: Islam M. S. , Tariq A. S. B. , Joardar S. K. , Uddin M. A. , Basak A. K.
Published: September 2024

A review on the research contributions from the nuclear and particle physics laboratory of Rajshahi University is presented. Special emphasis has been given to the nuclear physics research using the molecular nucleus-nucleus (NN) potentials derived from the Pauli-laden energy density functional (EDF) theory. The successes of EDF-derived non-monotonic (NM) NN potentials, compared to other familiar optical model potentials such as Woods-Saxon (WS), Squared Woods-Saxon (SWS), double folding (DF) for NN interactions, have been discussed. The phenomenal successes of NM potentials with a repulsive core have been found to suggest that the true nature of NN potential is NM with the Pauli-compliant EDF as its root.
Modal and Spectrum Analysis of Vibration-Free Transportation System Using Finite Element Analysis
Authors: Kumar S. M. , Nagarajan V. A. , Iyyappan S.
Published: September 2024

The transportation trailer system comprises numerous delicate components that require careful handling throughout transit. During transportation, the system is subjected to vibrations and shock loads resulting from road conditions, trailer acceleration, and deceleration. If these loads are transferred to the system, it could adversely affect many of its elements, particularly at resonance. To mitigate such vibration-induced stress on the system, a vibration isolation system has been designed and analyzed. The transportation system is modelled and analyzed using the finite element method. The Power Spectral Density (PSD) based on ISO-8606 standard for random road profiles is utilized for spectrum analysis computations in the Finite Element Analysis (FEA). Natural frequencies in the transportation system with isolator obtained from the finite element analysis are compared with the mathematically calculated values and any discrepancies are reported as error percentages.
Modelos Autorregresivos para Predecir la Velocidad del Viento en la Zona Rural Socabaya de Perú, 2022
Authors: Quispe Reynaldo , Huamani Renzon
Published: September 2024

La zona rural del Perú presenta una gran variabilidad de vientos, su desconocimiento debido a la ausencia de modelos de predicción tiene un efecto desfavorable en la agricultura, infraestructura, seguridad, transporte y optimización de la energía eólica. Este trabajo obtiene un modelo de media móvil integrada autorregresiva (ARIMA) de predicción de la rapidez de viento en el lenguaje de programación R para la zona rural del Perú, distrito de Socabaya de Arequipa. La metodología consiste en el método cuantitativo y técnica documental, con una muestra de 334 datos de viento del año 2022 de la estación meteorológica Administración Nacional de Aeronáutica y Espacio (NASA) (POWER, 2023) para el distrito de Socabaya. Utilizando R, se aplicó el método paramétrico: Dicker-Fuller, Levene, D'Agostino, Kwiatkowski–Phillips–Schmidt–Shin (KPSS) y diferenciación (d=1) para lograr la normalidad y estacionariedad de los datos. Se analiza la función de autocorrelación simple (ACF) y función de autocorrelación parcial (Parcial ACF) mediante un proceso de ajuste recursivo, criterio de información de Akaike (AIC) para elegir el mejor modelo ARIMA de predicción. El resultado obtenido es el modelo de predicción de viento ARIMA (1, 1, 2), con una precisión de error de escala absoluta de media (MASE) de 0,849. Se concluye que el modelo ARIMA obtenido puede usarse para predecir la velocidad de viento en Socabaya a corto plazo, desde el 29 de noviembre hasta 8 de diciembre del 2022, y su aleatoriedad estaría influenciado por la variabilidad climática y cantidad de datos del año 2022.
Closed-loop Speed Control for a Three-Phase Alternating-Current Motor using a Modbus Network
Authors: Rodríguez Martín , Jara Ricardo , Baes Mario , López Yadira , Orozco Santos
Published: September 2024

This paper presents a closed-loop controller for speed regulation of a three-phase induction motor by means of a Modbus network, which is compound only by industrial-purpose hardware, namely two programmable logic controllers, a human-machine interface and a variable-frequency drive. This represents a step beyond the state of the art because the results in similar works reported in the literature were obtained using personal computers, academic-purpose hardware or a combination of both academic-industrial technologies. The speed regulation was achieved through a proportionalintegral controller executed in a programmable logic controller, whose feedback was supplied by another similar device completely dedicated to read and decode an industrial optical encoder; furthermore, the control signals were commanded to the alternating current motor using a variable-frequency drive. The proposed control network was tested through diverse regulation experiments, under different conditions, in order to assess its effectiveness and robustness. The obtained results were successful in terms of accuracy of the speed set-point tracking in comparison to the most similar works of the state of the art, namely zero steady-state error was achieved, 12 seconds earlier for 75% larger references and 22% less RMSE than other works, which are the best results reported so far. Such successful achievements encourage the later implementation of more advanced control techniques on three-phase-motor based industrial machinery using only industrial-purpose hardware.
Diseño e Implementación de un Prototipo Portable de Generación Piezoeléctrica
Authors: Portilla Miguel , Ludeña Raúl , Asanza Víctor , Dávila Miguel , Nevarez Manuel
Published: September 2024

Este documento presenta una investigación sobre el diseño y evaluación de un sistema de recolección de energía piezoeléctrica utilizando una alfombra con múltiples elementos piezoeléctricos. La investigación inicia con una introducción sobre la importancia de desarrollar fuentes alternativas de energía renovable para dispositivos electrónicos portátiles. Posteriormente, se presenta una revisión de literatura sobre tecnologías de recolección de energía del movimiento humano, enfocándose en materiales piezoeléctricos. La metodología describe el diseño de un prototipo de alfombra piezoeléctrica compuesta por una capa de goma, una lámina de acrílico y múltiples elementos piezoeléctricos conectados en paralelo a un circuito recolector de energía. Se realizaron pruebas para caracterizar la respuesta de los sensores piezoeléctricos y evaluar el sistema de recolección de energía bajo diferentes configuraciones. Los resultados indican que un solo elemento generó 18,59 uJ, mientras que 10 elementos conectados produjeron 297,4 uJ con un voltaje de 0,57 V. Además, el sistema permite la adquisición remota de datos a través de la plataforma IoT Thingspeak.
Uso de Minimización Irrestricta de una Función Espectral para Estimar la Zona Visible en Matlab 19.0
Authors: Quispe Reynaldo , Juli Verónica
Published: September 2024

Debido a la simplicidad y amplia aplicabilidad, la minimización irrestricta en la zona visible (Vis) es una herramienta importante para resolver muchos problemas de optimización de parámetros y condiciones operativas de sistemas fotovoltaicos. El propósito de este trabajo es usar la minimización irrestricta de una función objetivo simplificada ξ para estimar la zona Vis. Utilizamos el método cuantitativo y técnica documental, con una muestra de 34 datos experimentales Vis de la estación de la Universidad Heredia. Se utilizó el Software Matlab 19.0 y se aplicó el método paramétrico: minimización de un modelo matemático mediante el algoritmo básico con corrección de Armijo mediante el backtracking. El resultado obtenido es un optimizador factible de ξ en 33 iteraciones, la cual determinó un modelo de transferencia de la zona Vis de turbidez por aerosoles () 3,69x10-2 y capa de ozono (l) 57,40x10-2 cm con parámetros estadísticos de incertidumbre 0,132%, 2,066% para el error de sesgo medio relativo (rMBE) y error cuadrático medio relativo (rRMSE) respectivamente. Se concluyó que la atmósfera de la Universidad Heredia presenta un cielo blanco alternado turbio sin agujero de ozono.
Vitamin D Prevents Gestational Diabetes Mellitus via Modulating Glucose Metabolism in a Mouse Model
Authors: Gu S , Chen S , Liu Y
Published: September 2024

Gestational diabetes mellitus (GDM) is a common disease during pregnancy that has adverse effects on both the mother and fetus. There is currently rare researches on the effect of vitamin supplementation on GDM pregnant mother and their offspring on animal and cell levels systematically. This work supplemented the GDM pregnant mouse model with vitamin D and found that vitamin D can effectively alleviate the hyperglycemia in GDM pregnant mice, increase blood insulin and adiponectin concentrations, and improve GTT and ITT in pregnant mice. In addition, vitamin D can reduce the incidence of death and high birth weight of offspring caused by GDM. The offspring of GDM pregnant mice had higher blood glucose levels in the first 5 weeks after birth compared to the normal group, and then returned to normal levels. Vitamin D can alleviate abnormal glucose metabolism in newborn mice. The therapeutic effect exhibited by vitamin D may be due to their anti-inflammatory effects, as vitamin D supplementation significantly reduces the levels of TFN-α, MCP-1, IL-1β and IL-8 in the blood. Vitamin D also regulates liver lipid metabolism, resulting in a decrease in liver lipid accumulation and a decrease in blood triglycerides (TG) and cholesterol (CHO). The results of this study demonstrate that vitamin D supplementation can serve as an effective treatment strategy for alleviating GDM symptoms.
Randomizált, kontrollált klinikai vizsgálatok nem traumás agyállományi vérzésben
Authors: Hornyák Csilla , Bereczki Dániel
Published: September 2024

Egy kezelési eljárás hatásosságát és biztonságosságát megfelelően tervezett, randomizált kontrollált klinikai vizsgálatokkal lehet megbízhatóan igazolni. A stroke (magyarul: szélütés, gutaütés, agyi érkatasztrófa) kezelési eljárásait elemző vizsgálatok túlnyomó többsége az ischaemiás típusra irányult, míg a súlyosabb kimenetelű agyállományi vérzésekkel aránytalanul kevés randomizált vizsgálat foglalkozott. Ezekben a vizsgálatokban a klinikai végpontokat tekintve 2023-ig nem sikerült statisztikailag szignifikáns hatást igazolni. Az áttörés 2023-ban történt: egy sebészi és egy konzervatív kezelési stratégiát elemző vizsgálatban is jobb kimenetelt találtak, mint a kontrollcsoportban. Az agyállományi vérzések kezelésére irányuló jelenlegi randomizált vizsgálatok területei: a műtéti kezelés (a vér eltávolítása, dekompresszív craniotomia, különböző műtéti technikák elemzése); a vérzés mérséklése (vérnyomáscsökkentés, aktivált VII. alvadási faktor, tranexamsav); a perifokális oedema csökkentése (ozmoterápia, gyulladásgátlók); a vérzés körüli szövet védelme (neuroprotekció); valamint a szövődmények megelőzése. Külön csoportot képez a véralvadásgátló kezelés mellett kialakuló agyállományi vérzés utáni prevenciós teendők vizsgálata. Az agyállományi vérzésekre irányuló korábbi vizsgálatokat a MEDLINE és a Cochrane-adatbázisok, a jelenleg beteget bevonó randomizált vizsgálatokat az amerikai ClinicalTrials.gov és az európai clinicaltrialsregister.eu adatbázisok elemzésével tekintjük át.
TÜRK DEVLETLERİ TEŞKİLATININ DİL POLİTİKASI
Authors: Akın Cüneyt , Polat Zelkif
Published: September 2024

Türk Devletleri Teşkilatı, kuruluş felsefesi bakımından bir dil-politik temel (Türk Dili Konuşan Ülkeler İş birliği Konseyi-Türk Konseyi) üzerine inşa edilmiştir. Avrupa Birliği ise, ekonomi-politik bir temel üzerine (Kömür Çelik Birliği) inşa edilmiştir. Avrupa Birliği’nin yapısında bir dil birliği olmayışına çözüm olarak geliştirilen farklılıkta birlik düşüncesi, uzlaşma kültürü ile temelleri atılmış bir birlik (AB) için yerinde bir düşünce olarak görülebilir. Türk devletleri için ise uzlaşma, farklılıkta birlik yerine, aynılıkta birlik üzerine inşa edilebilir düşüncesindeyiz. Türk devletleri için aynılık, en başta dil için söz konusudur. Bu durumda Avrupa Birliği’nin farklılıkta birlik düşüncesinin aksine, ortak dil, din ve tarihin oluşturduğu kültürel kalıtımın Türk Birliği oluşturmada bir başat unsur olarak kullanılması sağlanmalıdır. Dolayısıyla, gelecekte kurulabilecek bir Türk Birliği modelinde ilk uzlaşma maddesi dil birliği olmalıdır. Çalışmada, söz konusu dil birliği bağlamında bağımsız Türk devletlerinin dil politikaları ve Türk Devletleri Teşkilatının dil politikası ele alınacaktır. 12 Kasım 2021 tarihinde kurulan Türk Devletleri Teşkilatı'nın Türk Birliği'ne dönüşme yolunda atması gereken adımlardan biri, Türk devletleri arasında ortak bir yazı dili ve alfabeye geçişi sağlamaktır. Ancak, bu konuyla ilgili olan 121 maddelik bildiride herhangi bir bahse rastlanmamaktadır. Dolayısıyla, ortak iletişim dili üzerine atılacak adımların, Türk Devletleri Teşkilatı zirvelerinde alınacak kararlarla bildirilmesi ve “dil politik” temeller üzerine inşa edilen Türk Devletleri Teşkilatı’nın, bu çerçevede daha somut adımlar atması gerekmektedir.
BUHRANLI DÖNEMİN SADRAZAMLARINDAN AHMED ESAD PAŞA
Authors: Aykurt Çetin
Published: September 2024

XIX.yüzyılda Osmanlı Devleti’nin içine düştüğü buhranı atlatmak için gayret gösteren devlet adamlarından birisi de Ahmed Esad Paşa’dır. Mekteb-i Harbiyye’den, Erkân-ı Harbiyye yüzbaşısı olması ile birlikte devlet kademelerinde görev almaya başlamıştır. Birer defa Dâr-ı Şûrâ-yı Askeriyye reisliği ve Bahriye nâzırlığı ve iki defa sadrazamlık görevlerinde bulunmuştur. Bunun yanında Konya, Suriye ve Aydın valiliklerini yapmıştır. Paris sefâreti ataşemiliterliği görevinde bulunması Batıyı daha iyi tanımasına katkı sağlamıştır. İdareciliği esnasında taltiflerinin yanında azilleri de söz konusudur. Bu azillerin olmasında Ahmed Esad Paşa’nın çevresindekilerin padişahı etki altında bırakması önemli etkenlerden biri olmuştur.
Ahmed Esad Paşa, Cemiyyet-i Tedrîsiyye-i İslâmiyye adlı eğitim kurumunun kurucularındandır. Yine Ahmed Esad Paşa’nın teklifi ile Dârüşşafakati’l- İslâmiyye adıyla bir mektep kurulmuştur. Bu mektepte Ahmed Esad Paşa’nın Paris’ten getirdiği ders programı uygulanmıştır.
Ahmed Esad Paşa, atandığı görevlerin bazılarında birlikte çalıştığı kişilerin teveccühünü kazanmıştır; ancak bu durum yönetimdeki diğer kişilerin onu kıskanmasına ve bir müddet sonra aleyhinde ortam oluşturulmasına sebep olmuştur. Aleyhinde yürütülen faaliyetlerde en büyük argüman da genç ve tecrübesiz bir kişinin nasıl sadrazamlığa atandığı olmuştur. Bu ortam onun Sultan Abdülaziz’in gözünde yıpranmasına neden olmuştur.
Ahmed Esad Paşa, Konya Valisiyken Orta Anadolu’da çıkan kuraklık esnasında gösterdiği basiretli tutumu ile yöre halkının takdirini kazanmıştır. Bu husus şiirlere de yansımıştır.
Ahmed Esad Paşa’nın Balkanlar’da çıkan isyanlarda gerekli inisiyatifi kullanmaması kendisi için eleştiri konusu olmuştur. Buna karşın döneminde ivme kazanan ekonomik buhranda da örnek davranışlar içinde bulunmuştur.
KLASİK TÜRK ŞİİRİNDE HZ. YÛSUF VE RİŞTE-İ PÎRE-ZEN ÜZERİNE
Authors: Yılmaz Bahar
Published: September 2024

Klasik Türk şiirinin mecrasında dinî, mitolojik, efsanevî ve tarihî pek çok kişi, olay ya da durumla karşılaşmak mümkündür. Şiirsel düzlemdeki kurguyu tasvir etmek isteyen şair, çeşitli bağdaştırmalardan yararlanmaktadır. Klasik Türk şiiri okuyucusu, herhangi bir dȋvânı eline aldığında kelimelerin anlamlarını bilse bile bazı mazmunları anlamakta güçlük çekebilmektedir. Okur, şiirsel bağlamda doğru bağdaştırmayı yapamazsa şiiri yanlış bir şekilde yorumlayabilmektedir. Bu bağdaştırmalar sadece eş zamanlı olmayıp aynı zamanda artzamanlı olarak da dinî mitolojik, efsanevȋ ya da tarihȋ kişi, olay ya da durumlar olabilmektedir. Telmih olarak adlandırılan bu sanatın ana figürlerinden biri de peygamberlerdir. Başta Muhammed, İsâ, Mȗsâ, Ya‘kȗp, Yȗsuf, Ȃdem, Hızır, Süleymȃn olmak üzere pek çok peygamberin sıra dışı olarak nitelendirilebilecek hadiseleri, klasik Türk şiirinin dünyasını şekillendiren önemli birer malzeme olarak okuyucunun karşısına çıkabilmektedir. Bu çalışmanın konusu olan Hz. Yȗsuf ve pazarda satılırken yaşlı bir kadının ona eğrilmiş iplerle talip olma hikȃyesi ise klasik Türk şiiri okuyucusu için hazırlanmış baş ucu kaynak olarak nitelendirilebilecek kitaplarda yer almayan bir hadisedir. Zaman zaman dîvânlarda geçmekte olan bu hadisenin kutsal kitaplarda da yer almadığı görülmüştür. Kutsal kitaplarda yer almamasına rağmen mevzubahis hadisenin neredeyse bütün Yȗsuf u Züleyhȃ mesnevilerinde yer alması dikkat çekicidir. Bu çalışmanın amacı, söz konusu hadisenin şiirsel imgelemde kazandığı anlamı, doğru bir şekilde yorumlayabilmektir. Çalışmada öncelikle Hz. Yȗsuf ve yaşlı kadın arasındaki ilginin anlaşılması için hadisenin mesnevilerdeki görünümü ile ilgili genel bir bilgi verilmiştir. Daha sonra ise dîvânlardan seçilmiş örnek beyitler, mesnevilerden edinilmiş bilgilerin ışığında analiz edilmiştir.
THE RELATIONSHIP BETWEEN MUSIC, TECHNOLOGY, AND LISTENERS IN THE DIGITAL AGE
Authors: Tabak Cihan , Aysu Güzel Gülsüm
Published: September 2024

This article analyses the intricate dynamics of music technology's growth and its effect on listener involvement and the economic framework of the music industry. These highlights are the crucial significance of technical advancement in revolutionising the process of creating, distributing, and consuming music, specifically emphasising the shift from conventional to digital media. The study highlights the need to grasp historical backgrounds, technological milestones, and legal issues in understanding the intricate connection between artists, listeners, and the industry in the digital age. Therefore, seeks to elucidate the diverse effect of music technology on listener engagement and economic factors through thorough analysis, including case studies and projections for the future. This article advocated for considering ethical considerations, fostering ties between artists and listeners and investigating new business structures to create a sustainable and thriving music ecosystem amidst the continuous digital transformation.
OSMANLI’DA KADINLARIN SOSYAL GÜVENLİK HAKLARI VE EMEKLİLİĞİ MESELESİ
Authors: Özger Yunus
Published: September 2024

Sosyal Güvenlik sisteminin en önemli bileşenlerinden biri olan emeklilik hakkı, çalışma hakkıyla doğrudan ilgilidir. Klasik dönem Osmanlı devlet teşkilatında kamu hizmetleri, yönetici sınıf mensubu erkekler tarafından görülmekteydi. İlmiye, seyfiye ve kalemiye mensuplarının kendilerine özgü sosyal güvenlik ve emeklilik hakları vardı. Yönetici sınıfın emekli olduğunda alacağı maaş tutarları Fatih Kanunnamesinde yer almaktadır. Ancak söz konusu kanunnamede kadınların emeklilik haklarına dair bir işaret yoktur. Kadınlar, bu dönemde ilgili sınıflarda aktif olarak görev alamayıp, çalışamadıklarından emeklilik haklarından da yoksundular. O halde Osmanlı kadınları ilk olarak ne zaman emeklilik hakkı elde etti? Emekliye sevkleri nasıldı? Bu araştırmada bu soruların cevabı arandı.
Osmanlı kadınları arasında emeklilik hakkını ilk olarak saraya köle statüsüyle alınan kadınlar elde etti. Dışarıya saraylı unvanıyla çıkan kadınlar çerağ adıyla emekliye ayrılırlardı. Çerağ uygulaması, Osmanlı kadınlarının hak ettikleri ilk emeklilik sistemidir. Osmanlı kadınları, ikinci önemli emeklilik hakkını ise XIX. yüzyılın son çeyreğinde kazandı. Eğitim ve sağlık başta olmak üzere kamu sektöründe memur olarak göreve başlayan kadınlar, prim esaslı modern sosyal güvenceye sahip oldular. Hizmet süresinin dolumu, yaş haddi veyahut malulen emekli olabildiler. Kadınların diğer bir sosyal güvenlik hakkı ise çalışamadıkları dönemler için tahsis edilen mazuliyet maaşı uygulamasıdır. Kamu hizmetinde çalışmayan kadınlar ise eşleri ya da babalarının memuriyetlerine bağlı olarak sosyal güvenceye tabi tutuldular.
GÖKTÜRKLERİN VE SAKALARIN BAŞKENTİ: ALTIN DAĞ
Authors: Şengül Fatih
Published: September 2024

Birinci Göktürk devletinin Bumin Kağan tarafından kurulmasını takip eden dönem içerisinde devletin batı kanadı kardeşi İstemi Han tarafından yönetilmeye başlanmış idi. İstemi Han batı yönünde devleti genişletmiş ve Maveraünnehir bölgelerine kadar olan sahaları ele geçirmişti. Tarihi kaynaklarda Batı Göktürklerin başkentinin adı Ming Bulak olarak geçmektedir. Son yapılan araştırmalar Ming Bulak isimli sahanın ile günümüzde Güney Kazakistan’ın Kırgızistan ile birleştiği noktadaki Jambıl vilayetinin Merke ilçesine 60 km. uzaklıkta yer alan Miŋ Bulak olduğunu kanıtlamıştır. Bizanslı yazar Menander Bizans elçisi Zemarchos’un mahiyetindeki heyet ile birlikte İstemi Han’ın sarayını ziyaret ettiğini ifade etmekte ve bu ziyaret ile alakalı verdiği bilgiler arasında coğrafi yer adı olarak Ektağ ismi geçmekte ve Menander Ektağ adını Türklerin Altın Dağ adını verdikleri dağ kitlesi ile ilişkilendirmeye çalışmaktadır. Bir başka Bizanslı yazar Thephylactos Simocattes ise Bizans imparatoru Maurice’ye Göktürk kağanından gelen mektubu zikrederken Altın Dağ isimli dağı zikreder. Bu makalede Menander ve Thephylactos Simocattes tarafından zikredilen Altın Dağ adlı coğrafya Sakaların Büyük İskender ile mücadelesini anlatan Şu Destanı’nda geçen Altun Kan isimli coğrafya ile ilintilenmektedir.

Cho-Shu ve Sui-shi isimli Çin kaynaklarında geçen Göktürklerin atalarının yurdunun bulunduğu muhitle alakalı sunulan bilgiler ışığında Türklerin cedlerinin yurdunun Kazakistan’daki Tasmola arkeolojik kültür sahası olarak teşhis edilmiş ve Türkler ile Sakalar arasında deliller ortaya konulmuştur. Bu çalışma bu türden bir görüşü teyit edecek cinsten Batı Göktürk Devleti’yle ilintili olaylar bahsedilirken ismi geçen Altın Dağ isimli dağın esasen Göktürklere intikal etmiş Saka kökenli bir adlandırma olduğu gerçeği üzerinedir.
Peningkatan Komitmen Profesi Guru Melalui Kepemimpinan Transformasional Kepala Sekolah, Budaya Organisasi, Dan Motivasi Berprestasi
Authors: Sukoco Hadi , Hidayat Rais , Muharam Hari
Published: September 2024

IMPROVING TEACHERS' PROFESSIONAL COMMITMENT THROUGH PRINCIPALS' TRANSFORMATIONAL LEADERSHIP, ORGANIZATIONAL CULTURE, AND ACHIEVEMENT MOTIVATIONThis research aims to find effective and efficient ways to increase teachers' professional commitment by examining the influence of variables that are thought to have a relationship with teachers' professional commitment. These variables are Transformational Leadership and Organizational Culture. and Achievement Motivation. The methods found are then used as input and recommendations to teachers, school principals, management or foundations, school supervisors, and the education department. This research also attempts to identify indicators of research variables that need to be improved and those that need to be maintained. This research uses a survey method with path analysis techniques (Path Analysis).  The population in this study was 358 Permanent Foundation Teachers in 46 Private Middle Schools in Pancoran Mas District, Depok City. The sampling technique in this research used a proportional random sampling technique using the Slovin formula with an error margin of 5%. The number of samples used in this research was 189 GTY respondents in private junior high schools in Depok City District. The research results show a positive direct influence of transformational leadership on teachers' professional commitment through achievement motivation and a positive direct influence of organizational culture on teachers' professional commitment through achievement motivation.
Manajemen Strategi Guru Menghadapi Kurikulum Merdeka di Sekolah Menengah Pertama
Authors: Damayanti Alvina Dwi , Hasanah Silviatul , Lestari Prihatin
Published: September 2024

The relationship between management as an important element in educational management with strategy as a way of implementing management has a close relationship. As a unified system, strategic management is indispensable in helping to implement an independent curriculum. The transformation of the implementation of the previous curriculum with the independent curriculum currently implemented by the government has quite specific developments. The use of technology, varied teaching materials and various methods that must be learned well by teachers today.  This study aims to examine teachers' strategic management in dealing with the "Independent Curriculum" in Junior High School (SMP) at Hasanuddin 6 Semarang Junior High School and analyze the obstacles that exist in implementing the "Independent Curriculum". This research is descriptive research with a qualitative approach. Data collection is done through observation, interview and documentation techniques. The data collected was then analyzed qualitatively in three stages; data reduction, data presentation and conclusion drawing. The results showed that there are important things that must be prepared in implementing an independent curriculum at school. Based on the results of the research, strategic management needs to pay attention to 3 aspects, how to plan, provisions in implementation and evaluation forms in an independent curriculum.  As an educational institution that carries out its functions systematically, the most effective form of evaluation is by paying attention to planning, organizing and implementing to minimize failure.
PERAN GURU PENDIDIKAN AGAMA ISLAM DALAM MENINGKATKAN MINAT MEMBACA DAN MENULIS AYAT AL-QURâ€™AN Studi kasus di SMP Ungglan Al-Ittihad Rejoslamet Mojowano
Authors: Farera Putri Ayu , Surur Shobihus
Published: September 2024

Abstract : This scientific research aims to describe and analyze the role of a teacher in the process of learning to read and write at the Al-Ittihat Rejoslamet Mojowarno Superior Junior High School. A descriptive approach was taken in this study. Observations, interviews, and documentation are examples of data collection methods. The primary data sources were obtained from 3 students of Al-Ittihat Rejoslamet Mojowarno Superior Middle School, 1 PAI teacher, and the Principal of Al-Ittihat Superior Middle School. Meanwhile, secondary data sources include books, document files, and researcher notes; researcher documentation and other supports; and statistics on the number of students and professors at Al-Ittihat Rejoslamet Mojowarno Superior Junior High School.In this study, it was found that PAI teachers played an important role in fostering interest in reading and writing verses of the Qur'an, as evidenced by three reading indicators: (1) fluency in reading the Qur'an, (2) accuracy in reading the Qur'an in tajwid, and (3) the suitability of the reading with its makhraj. In addition, there are three types of writing indicators: writing single letters, writing vowels, and writing conjunctions containing many letters, sentences, and phrases.
KEGIATAN ENTREPRENEUR DALAM MENUMBUHKAN KEMANDIRIAN SANTRI DI ERA MODERN
Authors: Syah Maulana Fuadi , Umam Khoirul
Published: September 2024

Abstract: Entrepreneurial activity is an activity in which it teaches creative ways to create an activity that can provide additional knowledge, especially in the world of economics, besides that this activity can provide independence to a student because in it a student is required to be creative and productive. in every activity of his life, including in terms of dividing time between pesantren activities and entrepreneurial activities. The focus of this research includes: 1) Entrepreneurial Activities in Fostering Student Independence in the Modern Era (Case Study at Pondok Pesantren At Tahdzib Ngoro Jombang). 2) Inhibiting and supporting factors of entrepreneurial activity in fostering student independence in the modern era (Case Study at Pondok Pesantren At Tahdzib Ngoro Jombang).
This type of research uses a case study approach to find out something in depth. This research is included in qualitative field research. Data collection techniques in this study use interview, observation, documentation and triangulation techniques which are then analyzed. From the results of this study, entrepreneurial activities without us realizing this activity are activities taught by Salafus Sholeh in educating his students with the aim that after graduating from the pesantren world they are able to become independent students, meaning that students returning from boarding schools can practice their religious knowledge from their needs. community, and can have a job from entrepreneurial activities that have been taught from boarding schools (Entreprenuer Skills)
PENGARUH AMALIYAH IBADAH SHALAT JAMAAH TERHADAP KEDISIPLINAN SANTRI DI PONDOK PESANTREN PUTRI WALISONGO CUKIR JOMBANG
Authors: Hajarul Husna Dewi , Anshori Sholihul
Published: September 2024

to carry out the practices that have been regulated by Islamic law. One form of worship that must be fulfilled is congregational prayer. Congregational prayer is a form of teaching for a Muslim to have a disciplined attitude. With discipline, life will be more organized and it will be easy to achieve success in life. The following are research objectives 1) To discover the amaliyah of congregational prayer at PPP. Walisongo Cukir Jombang. 2) To discover the discipline in PPP. Walisongo Cukir Jombang. 3) To discover the influence of amaliyah worshiping congregational prayers on the discipline of students in PPP. Walisongo Cukir Jombang. This study employs a quantitative method.. The population at the PPP. Walisongo Cukir Jombang is 1.400 students, so a sample of 140 students was taken. Data collection in this study pass the use of a questionnaire distribution. Descriptive analysis is the method of data analysis used, prerequisite testing stage and simple analysis of linear regression with the help of SPSS 17. The study's findings lead to the following conclusion 1) The practice of congregational prayer at PPP. Walisongo Cukir Jombang is in the good category, because the score obtained lies between a score of 56-64. 2) Discipline of students at PPP. Walisongo Cukir Jombang is in the pretty good category, because the scores obtained lie between scores of 29-37. 3) There is a substantial connection between the amaliyah of congregational prayer services on the discipline of students at PPP. Walisongo Cukir Jombang. The extent  of the influence of amaliyah worship in congregational prayers on the discipline of students is 18.6% and the remaining 81.4% is influenced by other non-examined aspect.
Implementasi Nilai-Nilai Tasawuf Dalam Membentuk Karakter Santri Di Era Globalisasi Di Pondok Pesantren Majma’al Bahroin Hubbul Wathon Minal Iman Losari Ploso Jombang
Authors: Aziz Fuad , Jumari  , Salim M. Nur
Published: September 2024

Sufismiis aiscientific discipline thatistudies theigood andibad ofitheisoul, as well as how to cleanse it of bad things and fill it with good qualities. This is done by performing suluk and journeying towards (the pleasure of) Allah SWT and leaving (prohibitions) towards (his commands). The Majma'al Bahrain Islamic Boarding School teaches the values of Sufism, leading students to have good and commendable behavior. Theiaim ofithe researchiis toifind outiwhether theimorals of Sufism which really need to be implemented in this era of globalization, whether the students have implemented them, to find out whether in the boarding school there has been a study of the values of Sufism apart from learning to recite the Koran and classical books and to find out how determined santri in tolabul ilmi at the cottage. This research method is taken from qualitativeiresearch methods,iresearch that isidescriptive ininature and tendsito useianalysis. Theitheoretical basisiis also usedias aiguide soithat theifocus ofithis qualitativeresearchi method is correct in accordance withithe factsiin theifield. not talking about facts but the facts are talking. Theiresults ofithe research areithat students in Islamic boarding schools, apart from studying the Koran and classical books, also need to instill the values of Sufism because apart from faith and Islam in religious teachings there is also ihsan, cultivating everyday traits such as zuhud, wara and sincerity will make students get blessings. knowledge for the future. The application of the values of repentance, asceticism, patience and wira'i will continue to be taught and practiced in the teachings of the Majma'aliBahroin HubbuliWathonMinaliIman LosariiPloso Jombang Islamic Boarding School, in this era of globalization character formation is not based on cleanliness values Therefore, it is feared that there will be a wrong intention in seeking knowledge, so researchers are taking part in ensuring that this does not happen among studentsiin theiera of globalization iniIslamic boarding schools.i
Comparison of Giving Beet and Date on Haemoglobin Among Pregnant Women with Anemia
Authors: Hamidah Siti , Sulastri Sulastri
Published: September 2024

Aims : The purpose of this study is to evaluate the efficacy of administering beets and dates to pregnant women who have moderate anemia in terms of boosting their hemoglobin levels.
Method : This research design employs a quasi-experimental study approach, which includes a pre-test and a post-test, as well as research instruments that make use of observation width and hydrogen bond level measuring equipment. It is the paired t-test that is utilized as the statistical test.
Results : In the beetroot group, the results obtained were a mean pre test of 10.09 and a mean post test of 12.2 so it can be concluded that the mean difference is 1.3 (10.09- 12.2) and P value = 0.329 (P > α) so It can be concluded that the comparison of increasing hemoglobin levels in the beetroot group is more effective than the dates group for pregnant women in the third trimester at BPM Siti Hamidah
Conclusion : Giving beetroot juice is more beneficial in boosting the HB levels of pregnant women with mild anemia, according to BPM Siti Hamidah.
Is Gender Diplomacy Effective? Women’s Representation and Public Diplomacy in Authoritarian Regimes
Authors: Benstead Lindsay J. , Sari-Genc Elif
Published: September 2024

Extant scholarship suggests that autocrats employ quotas to cultivate an image of democratic governance, yet the mechanisms underlying these effects are underexplored. We conceptualize Gender Diplomacy (GD) as the strategic deployment of women in public diplomacy to enhance foreign perceptions. We conducted a nationally representative survey, randomly exposing 1,241 Americans to vignettes and photos depicting either an all male or a gender balanced Federal National Council in the UAE. Our findings reveal that GD improves perceptions in domains associated with stereotypically female traits, including viewing the UAE positively, but weaker effects in domains associated with male competencies, such as support for security cooperation. We argue that these effects are due to the implicit association between female traits and the UAE. Our research underscores the role of implicit gender biases in public diplomacy and informs debates on the strategic use of women's inclusion.
Plastic pollution and health metrics in wild juvenile green sea turtles (Chelonia mydas) from two Ecuadorian national parks: Galápagos and Machalilla
Authors: Muñoz-Pérez Juan Pablo , Lewbart Gregory A. , Toapanta Tania , Chadwick Helen , Okoffo Elvis D. , Alarcón-Ruales Daniela , Zurita-Arthos Leo , Jones Jen S. , Cisneros Fernando , Moreira-Mendieta Andres , Vintimilla-Palacios Cristina , Miranda Cristina , Vallejo Felipe , Houck Emma , Alemán Rubén , Escobar-Flores Kamila , Skehel Alice , Castañeda Jason , Secoura Patricia , Vaden Shelly , Lewis Ceri , Galloway Tamara , Wallace Bryan , Godley Brendan J. , Cole Matthew , Lindeque Penelope , Thomas Kevin V. , Potvin Dominique A. , Valle Carlos A. , Townsend Kathy A.
Published: September 2024

Marine vertebrates, particularly green sea turtles, are especially vulnerable to plastic pollution through ingestion or entanglement. This study investigated wild juvenile green sea turtles (Chelonia mydas) from two Ecuadorian national parks (Galápagos and Machallilla) to assess the prevalence of plastic pollution in their feces and its potential impact on various health metrics. We analyzed fecal samples from 46 juvenile green sea turtles using Fourier transform infrared spectroscopy (FT-IR) to quantify microplastics (MPs). A complementary methodology using pressurized liquid extraction with double-shot pyrolysis-mass spectrometry gas chromatography (Pyr-GC/MS) was also employed to quantify synthetic polymer mass concentrations. The results from these analyses were compared with blood analytes. FT-IR analysis revealed a mean of 4.4±5.2 MPs/g in fecal samples, with the highest quantities found in the Galápagos Marine Reserve (GMR). The most common MPs shape identified were fibers (x̄= 3.8±4.5 MPs/g), and the predominant synthetic polymers were polyvinyl alcohol (PVOH) and polyacrylates (PMMA). The daily intake of MPs by the sampled turtles ranged from a minimum of 312±409 MPs/day to a maximum of 430±563 MPs/day. Pyr-GC/MS analysis detected polyethylene (PE) with a mean of 367±1158 µg/g and polypropylene (PP) with a mean of 155±434 µg/g in fecal samples, with the highest pollution levels observed in the GMR. Both FT-IR and Pyr-GC/MS techniques detected plastic pollution in 98% of the sampled population. Although both FT-IR and Pyr-GC/MS are reliable methods, they produced slightly different results due to methodological variations. However, both supported the finding that turtles in the GMR were exposed to higher rates of plastic ingestion. Despite the turtles appearing clinically healthy based on blood analysis, significant differences in eleven health metrics were observed between turtles classified as less at risk and those most at risk for plastic pollution. Further research is necessary to understand the potential health implications of these findings.
Prognostic significance of muscle fasciculations in critically Ill COVID-19 patients under mechanical ventilation
Authors: Molinger Jeroen , Whittle John , Cha Susie , MacLeod David , Fudim Marat , Ulloa Luis , Barkauskas Christina , Healy Zachary , Haines Krista L. , Gupta Rajan T. , Endeman Henrik , van der Jagt Mathieu , Gommers Diederik , Bakker Jan , Wischmeyer Paul E.
Published: September 2024

Introduction

The COVID-19 pandemic brought unprecedented challenges to healthcare systems worldwide, particularly the often challenging physical recovery from critical illness. Among the myriad complications faced by these patients, ICU-acquired weakness (ICU-AW) stands out due to its significant impact on patient outcomes. ICU-AW, characterized by skeletal muscle atrophy and weakness, is linked to critical illness polyneuropathy (CIN), myopathy (CIM), and muscle atrophy. Notably, fasciculations, or involuntary muscle twitches, have been observed in patients with ICU-AW, suggesting altered muscle fiber excitability. This study aimed to describe the pattern of fasciculations in critically ill mechanically ventilated COVID-19 patients, assess clinical features associated with fasciculations, and evaluate their prognostic significance.

Methods

The study enrolled patients admitted to the Intensive Care Unit (ICU) with COVID-19 infection requiring intubation and mechanical ventilation. Quadriceps muscles were assessed using muscle skeletal (MSK) ultrasound and Phase Angle (PhA) through multifrequency segmental bioelectrical impedance analysis (MFBIA) every 72 h. PhA is considered a marker of cell membrane integrity and function, with lower PhA values indicating reduced skeletal muscle quality and increased risk of sarcopenia. Fasciculations were classified based on their appearance and frequency.

Results

A total of 35 intubated patients were studied, with 15 patients (43%) displaying scattered fasciculations exclusively in the vastus intermedius muscles. Upon admission, the study found no significant difference in PhA between the fasciculation and non-fasciculation groups. However, PhA decreased significantly from admission to discharge ICU only in the fasciculation group. Patients with fasciculations exhibited higher mortality rates, though not statistically significant, and this correlated with prolonged ICU and hospital lengths of stay.

Discussion

This study is the first to report scattered fasciculations in the vastus intermedius muscles of multiple patients with SARS-CoV-2 infection identified with MSK ultrasound. The findings suggest that the combination of impaired muscle cellular function (PhA) and the onset of fasciculations could serve as a potential biomarker of adverse outcomes and ICU-related muscle dysfunction and muscle loss.
Association of milk metabolites with feed intake and traits impacting feed efficiency in lactating Holstein dairy cows
Authors: James Leonora M. , Mayes Mary S. , Siberski-Cooper Cori J. , Breitzman Matthew W. , Vandehaar Michael J. , Koltes James E.
Published: September 2024

Genetic selection for feed efficiency is possible in Holstein dairy cattle. However, measuring individual cow feed intake is expensive, which limits available phenotypes, resulting in lower prediction accuracy of breeding values than desired. New indicator trait phenotypes for feed efficiency could help improve breeding value accuracies if they can be measured widely across dairy herds. The objective of this study was to identify milk metabolites associated with feed intake and efficiency traits that may serve as new indicator traits. Metabolites were obtained from three sources and two distinct groups of cows. Gas chromatography mass spectrometry (GC-MS), and liquid chromatography mass spectrometry (LC-MS) assays were conducted on a subset of 39 cows identified based on their extreme residual feed intake (RFI; top and bottom 15%). Routinely collected on-farm milk testing data were evaluated on a second, larger subset of 357 cows. Statistical models were created to evaluate if metabolites: 1) provided novel feed efficiency information; 2) served as proxies for body weight traits not routinely collected on farms; and 3) were associated with breeding values for feed efficiency traits, including: predicted transmitting abilities (PTA) for feed saved (FS), RFI and body weight composite (BWC). Ontology enrichment analysis was used to identify enriched pathways from the contrast of extreme RFI cows by GC-MS and LC-MS. The false discovery rate (FDR, reported as q-values) and Hommel corrections were used as multiple testing corrections. Partial least squares discriminate analysis confirmed animals could be classified as high or low feed efficiency groups. A total of 33 GC-MS metabolites, 10 LC-MS ontology pathways (both q<0.20) and 42 fatty acid or milk quality assays from on-farm tests (Hommel adj-p<0.05) were identified for analyses 1, 2, and 3 respectively. Ontology enrichment analysis of LC-MS data identified the sphingolipid metabolism (analysis 2), and beta-alanine metabolism (analysis 1) pathways (q<0.20). Heptanoic acid was identified as associated with PTA BWC (GC-MS, Model 3; q<0.15). These metabolites represent new candidate indicator traits for feed efficiency that could be included in existing on-farm milk testing systems upon validation.
Regulatory effect of N6-methyladenosine on tumor angiogenesis
Authors: YuYan  , Yuan Enwu
Published: September 2024

Previous studies have demonstrated that genetic alterations governing epigenetic processes frequently drive tumor development and that modifications in RNA may contribute to these alterations. In the 1970s, researchers discovered that N6-methyladenosine (m6A) is the most prevalent form of RNA modification in advanced eukaryotic messenger RNA (mRNA) and noncoding RNA (ncRNA). This modification is involved in nearly all stages of the RNA life cycle. M6A modification is regulated by enzymes known as m6A methyltransferases (writers) and demethylases (erasers). Numerous studies have indicated that m6A modification can impact cancer progression by regulating cancer-related biological functions. Tumor angiogenesis, an important and unregulated process, plays a pivotal role in tumor initiation, growth, and metastasis. The interaction between m6A and ncRNAs is widely recognized as a significant factor in proliferation and angiogenesis. Therefore, this article provides a comprehensive review of the regulatory mechanisms underlying m6A RNA modifications and ncRNAs in tumor angiogenesis, as well as the latest advancements in molecular targeted therapy. The aim of this study is to offer novel insights for clinical tumor therapy.
Influence of rheumatoid factor levels and TNF inhibitor structure on secondary nonresponse in rheumatoid arthritis patients
Authors: Plasencia-Rodríguez Chamaida , Martínez-Feito Ana , Novella-Navarro Marta , Pérez De Diego Rebeca , Bonilla Gema , Gehin Johanna Elin , Villalba-Yllán Alejandro , Nuño Laura , Pascual-Salcedo Dora , Nozal Pilar , Almirón Mariana Díaz , Balsa Alejandro
Published: September 2024

Background

The EXXELERATE study revealed poorer clinical outcomes in patients treated with adalimumab (ADL) and baseline rheumatoid factor (RF) above 203 IU/mL. However, responses were similar in patients treated with certolizumab pegol (CZP) regardless of RF levels.

Objectives

This study investigated the impact of RF levels >203 IU/mL on TNF inhibitors (TNFi) serum levels and the association with secondary nonresponse in RA patients treated with TNFi.

Methods

We performed an observational ambispective study with RA patients treated with infliximab (IFX), ADL, or CZP. Patients were stratified according to baseline RF levels: ≤ or >203 IU/mL. After 6 months, serum drug levels and antidrug antibodies were measured, and reasons for discontinuation were collected.

Results

We included 170 RA patients: 90 (53%) received IFX, 48 (28%) ADL, and 32 (19%) CZP. While CZP serum levels did not differ between RF groups at 6 months (p = 0.6), RF levels >203 IU/mL were linked to lower serum drug levels in patients treated with IFX (p = 0.09) or ADL (p = 0.02). Secondary nonresponse was 3.6 times higher in patients with high versus low RF levels in patients under IFX or ADL. However, the reasons for withdrawal were not affected by RF levels in patients treated with CZP.

Conclusion

Baseline RF above 203 IU/mL is associated with lower serum drug levels and an increased risk of discontinuation due to secondary nonresponse in patients treated with IFX or ADL. In contrast, drug levels and clinical outcomes are not significantly impacted by baseline RF levels in patients under CZP.
Metabolic changes that allow Plasmodium falciparum artemisinin-resistant parasites to tolerate oxidative stress
Authors: Bonive-Boscan Alejandro David , Acosta Héctor , Rojas Ascanio
Published: September 2024

Artemisinin-based treatments (ACTs) are the first therapy currently used to treat malaria produced by Plasmodium falciparum. However, in recent years, increasing evidence shows that some strains of P. falciparum are less susceptible to ACT in the Southeast Asian region. A data reanalysis of several omics approaches currently available about parasites of P. falciparum that have some degree of resistance to ACT was carried out. The data used were from transcriptomics and metabolomics studies. One mitochondrial carrier of the parasite possibly involved in the mechanisms of tolerance to oxidative stress was modeled and subjected to molecular dockings with citrate and oxoglutarate. An increase in glutathione production was detected, changing the direction of the flux of metabolites in the tricarboxylic acid cycle and boosting the glucose consumed. The models of the mitochondrial carrier, called PfCOCP, show that it may be important in transporting citrate and oxoglutarate from the mitochondrial matrix to the cytosol. If so, it may allow the parasite to tolerate the oxidative stress produced by artemisinin. This in-silico analysis shows that P. falciparum may tolerate artemisinin’s oxidative stress through metabolic changes not reported before, showing the need for further experimental research on the many metabolic aspects linked to this phenotype.