bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of the impact of Lupinus angustifolius L. flour on the rheological properties of wheat flour dough
Authors: Л. М. Присяжнюк  , С. О. Ляшенко  , І. В. Смульська  , Т. М. Хоменко
Published: May 2019

Purpose. To investigate the patterns of changing the rheological properties of the dough and laboratory baking, depending on the amount of flour from different varieties of lupine added to wheat flour. Methods. The baking quality was analyzed using an alveograph and farinograph. Results. Based on the evaluation of alveograph, farinograph and laboratory bread baking, the patterns of changing the rheological properties of the dough when adding lupine flour to wheat flour were determined. The share of lupine variety’s influenced on flour strength, elasticity and stretchability of the dough, elasticity index ranged from 1 to 4%, with flour concentration – 82–98%. On the basis of the obtained data of the regression equation for the dependencies between the alveographer parameters and the amount of lupine flour added to wheat one were determined. A linear relationship was established between the physical characteristics of dough and the concentration of lupine flour. The proportion of the lupine variety impact on the time of dough formation, rate of dough fluidizing, valorimetric estimation of the flour mixture was 4–18%, the concentration of lupine flour was 57–76%. The bread loaf volume was for 86% determined by the concentration of lupine flour and for 6% by lupine variety. Based on the regression equations between the physical properties of the dough and the concentration of lupine flour, an exponential, linear, and polynomial dependence were found. The linear dependence was revealed between the bread loaf volume and the concentration of lupine flour in a lupine-wheat mixture. Conclusions. The rheological properties of the dough, as well as the bread loaf volume, were most influenced by the concentration of lupine flour in lupine-wheat flour mixture (57–98%). The share of influence on these indicators of lupine varieties used in the study did not exceed 18%. The revealed regression equations between the concentration of lupine flour and the physical characteristics of the dough allow predic­ting their changes depending on the amount of lupine flour added to wheat flour.
Adaptability of potato varie­ties to soil-climatic conditions of the Polissia and Forest-Steppe zone of Ukraine
Authors: Т. Д. Сонець  , З. Б. Києнко  , М. М. Фурдига  , Ю. Я. Верменко
Published: May 2019

Purpose. To define the main criteria for adaptability and determine the adaptive capacity of different varieties of potatoes tested in Polissia and Forest-Steppe of Ukraine for use in seed production. Methods. The productive potential of potato varieties to determine overall species adaptability was analyzed in terms of yield. For this purpose, the coefficient of adaptability of varieties (CA) was used determined by their yield in the year of cultivation in ratio to the ave­rage yield of the year. Results. Over the years of research (2014–2016), under similar conditions of cultivation, the varieties responded in different ways to conditions of the environment in relation to the year of testing. The overall CA of 1.0 and higher indicates increased adaptability of the variety in the soil and climatic conditions of the growing area to changes in weather conditions during the growing season. In particular, in Polissia these are ‘Esmi’ (CA 1.12), ‘Catania’ (CA 1.06), ‘Constans’ (CA 1.03); in the Forest-Steppe – ‘Esmi’ (CA 1.16), ‘Catania’ (CA 1.12), ‘Constans’ (CA 1.00). Specific adaptive ability of varieties is manifested in high average variety yields in years favorable by weather conditions for potato cultivating. The increase in the yield of such varieties in Polissia was 0.4–1.9 t/ha, in the Forest-Steppe – 0.7–2.8 t/ha. ‘Esmi’, ‘Catania’, ‘Yavir’, ‘Constans’ belong to such varieties in Polissia, ‘Esmi’, ‘Catania’, and ‘Constans’ – in the Forest-Steppe. Conclusions. The use the coefficient of adaptability allows determining the productive capacity of a variety in specific soil and climatic conditions. The cultivation of potato varieties with increased adap­tability is a significant factor in increasing the production of high-yielding potato varieties, primarily seed material of high categories for varieties rotation and replacement. In particular, according to research results, such varieties of potatoes in Polissia and Forest-Steppe conditions are ‘Esmi’, ‘Catania’ and ‘Constans’.
An Assessment of the Contact History of Multi-Drug Resistant Tuberculosis Patients from Sindh: A Gender based comparison
Authors: Noori Muhammad Yahya , Rizwan Saharish , Ali Zaheer , Sharafat Shaheen
Published: May 2019

The purpose of this project was to evaluate the pattern of transmission in patients suffering from Multidrug resistant (MDR) Tuberculosis by assessing their contact information. Data were obtained and analyzed from 164 individuals suffering from MDR TB. Records were scanned to evaluate the presence ofa close contact with known history of Tuberculosis. Tabulations and analysis were performed in Microsoft Excel® and online calculators. Analysis of contact data showed that only 36% of the patients had a close contact with a known Tuberculosis patient. Chi-square test did not show any association between history ofpresence of a contact and the patients’ gender (p>0.5). Among the cases with established exposure with a TB patient among close contacts, 17.5% females and 12.5% males reported exposure with a contact outside the close family. Majority of patients were unaware of the presence of a known contact in their vicinity. There was no association between knowledge about exposure and patients’ gender. The study shows that efforts of active case finding should be employed to find the hidden cases of Tuberculosis in the society to stop the spread by those patients, who are unaware of their disease.
Comparison of Letrozole versus Danazol for the Pain Management of Females Presented with Endometriosis
Authors: Rasul Sadaf Ghulam , Yaqub Uzma , Manzoor Maida , Mubasshar Hafsa
Published: May 2019

Endometriosis is an estrogen-regulated disease, and is signified by the existence of a particular endometrial tissue exterior to the uterus. It is a principal cause of long lasting morbidity, mostly from serious pelvic pain(1). Endometriotic tissue has the potential for aromatase gene expression that leads to aromataseand estrogen production. Danazol is a synthetic androgen whereas Letrozole is aromatase inhibitor. This study was conducted to compare the mean decrease in visual analogue scale (VAS) pain score with Danazol versus Letrozole for the pain management of endometriosis in females. A total of 140 females fulfillinginclusion criteria were registered and an non-probability purposive technique of sampling was used. Diagnostic laparoscopy was conducted to make a diagnosis of endometriosis. Females were divided into two groups. Females in group A received treatment with Letrozole tablets (2.5 mg/day) and in group B receivedDanazol tablets (600 mg/day) for 3 months. Pelvic pain was assessed using VAS score and the mean decrease in pain score was assessed between two groups using independent sample student t-test. Results of this study demonstrate that the mean age of the patients was 29.99±5.80 and the mean pain score before treatment in Letrozole group was 3.04±1.01 while in Danazol group was 5.05±1.02. Post-three months of treatments, mean pain score was 2.01±0.95 and 2.78±0.99 in Letrozole and Danazol groups, respectively. The mean decrease in pain score in Letrozole group was 1.02±1.09 (p-value=0.00) while in Danazol group; it was 3.06±1.23 (p-value=0.00). This difference in pain score was considerably different in both treatment groups. A higher decrease in pain score was observed in Danazol compared to Letrozole treated groups.
Enhancing efficiency and economics of phosphorus recovery process by customizing the product based on sidestream characteristics – an alternative phosphorus recovery strategy
Authors: Shaddel Sina , Ucar Seniz , Andreassen Jens-Petter , Østerhus Stein W.
Published: May 2019

The enhanced biological phosphorus removal process makes the phosphorus recovery feasible from the dewatering streams of biological sludge. The physicochemical properties of these sidestreams, as an input to a crystallizer, are different before and after anaerobic digestion. In this study, phosphorus recovery by calcium phosphate is proposed for pre-digestion sidestreams and by struvite precipitation for post-digestion sidestreams. The thermodynamic modeling followed by experimental tests was performed to evaluate the recovery efficiency and product properties of struvite and calcium phosphates. The variations in phosphorus recovery potential, reaction kinetics and particle size distribution emphasize the importance of the adjustment of initial supersaturation and pH of the reaction. The optimum pH, considering the economics and recovery efficiency, for both calcium phosphate and struvite precipitation was found to be pH = 8.5, whereas further increase of pH will not improve the overall efficiency of the process. In the case of calcium phosphate precipitation, it was shown that possible phase transformations should be considered and controlled as they affect both process efficiency and product properties. The economic evaluation indicated that the optimized operational condition should be determined for the phosphorus recovery process and that chemical costs for the production of calcium phosphates is lower than for struvite.
The Importance of Precision Medicine in Type 2 Diabetes Mellitus (T2DM): From Pharmacogenetic and Pharmacoepigenetic Aspects
Authors: Khatami Fatemeh , Mohajeri-Tehrani Mohammad R. , Tavangar Seyed M.
Published: May 2019

Background:

Type 2 Diabetes Mellitus (T2DM) is a worldwide disorder as the most important challenges of health-care systems. Controlling the normal glycaemia greatly profit long-term prognosis and gives explanation for early, effective, constant, and safe intervention.

Materials and Methods:

Finding the main genetic and epigenetic profile of T2DM and the exact molecular targets of T2DM medications can shed light on its personalized management. The comprehensive information of T2DM was earned through the genome-wide association study (GWAS) studies. In the current review, we represent the most important candidate genes of T2DM like CAPN10, TCF7L2, PPAR-γ, IRSs, KCNJ11, WFS1, and HNF homeoboxes. Different genetic variations of a candidate gene can predict the efficacy of T2DM personalized strategy medication.

Results:

SLCs and AMPK variations are considered for metformin, CYP2C9, KATP channel, CDKAL1, CDKN2A/2B and KCNQ1 for sulphonylureas, OATP1B, and KCNQ1 for repaglinide and the last but not the least ADIPOQ, PPAR-γ, SLC, CYP2C8, and SLCO1B1 for thiazolidinediones response prediction.

Conclusion:

Taken everything into consideration, there is an extreme need to determine the genetic status of T2DM patients in some known genetic region before planning the medication strategies.
Effects of Two Phonics Instructional Modes on English as Second Language Learners’ Achievement in Reading
Authors: Amadi Eugenia Ada , Offorma Grace C.
Published: May 2019

This study examines the effects of two phonics instructional modes on the reading achievement of Nigerian learners of English as a second language. The design of the study was quasi-experimental. The study specifically adopted the non-equivalent, non-randomized control group design. The sample of the study were 118 primary one school pupils who were drawn from four public primary schools in Enugu, South East, Nigeria using multi-stage sampling technique. The participants who were assigned to experimental and control groups were pretested and post tested. The experimental group was taught using synthetic phonics while the control group was taught using analytic phonics. Data were generated with Means, Standard Deviation and Analysis of Covariance (ANCOVA). While Means and Standard Deviation were used to answer the research questions, ANCOVA was used to test the hypothesis at p<0.05. The findings of the study indicated that Synthetic phonics significantly improved pupils’ achievement in reading more than analytic phonics. Based on the findings, it was concluded that synthetic phonics is a more effective mode of teaching beginning reading than analytic phonics. A proper exposure of pre and in-service teachers to the techniques and activities involved in synthetic phonics as well as the adoption and proper implementation of the method for reading instruction in Nigerian primary schools were recommended.
Forward positioning and consolidation of strategic inventories
Authors: Skipper Joseph B , Bell John E , Cunningham William A , Mattioda Daniel D
Published: May 2019

The forward positioning of strategic inventory in the supply chain has an impact on transportation times and is important for sensitive demand profiles. Consolidation of stocks creates pooling effects and minimizes costs. This study analyzes a current military case where forward consolidation of equipment is considered using optimization, and payback periods are calculated for the cost of consolidating inventory at one of six locations. Results indicate that forward positioning and consolidation reduces time and cost, and also creates savings in reverse logistics flows. The study has implications for geographically diverse supply chains such as humanitarian aid and emergency response operations.
The relationship between measures of operations efficiency and financial success of truckload motor carriers: An empirical analysis
Authors: Johnston Ahren
Published: May 2019

This research paper examines the statistical relationship between clay to day performance and effi­ ciency measures and financial performance in the motor carrier industry. Key findings are that carriers with more miles per tractor per year, a larger average length of haul, more revenue per mile, and more revenue per tractor per week tend to perform better financially as measured in three separate models by operating ratio, return on assets, or return on equity. Unexpectedly, for the eight publicly traded carriers included in the analysis, there was a negative relationship between empty mile percentage and financial performance, indicating that carriers with a higher empty mile percentage have better financial perfor­ mance. Possible explanations for these counterintuitive results could be due to a focus on better cus­ tomer service or driver satisfaction causing slight increases in empty miles. Therefore the increased costs resulting from empty miles could be offset by higher revenue or decreased costs in other aspects of the operation. These results suggest that managers should focus not on minimizing empty miles but rather on keeping them within an acceptable range.
DIGITAL IMAGING, TELERADIOLOGY
Authors: Editorial Article
Published: May 2019

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IMAGING OF THE MUSCULOSKELETAL SYSTEM
Authors: Editorial Article
Published: May 2019

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Selection of sunflower hybrids based on stability across environments
Authors: Cvejic Sandra , Jocic Sinisa , Mladenov Velimir , Banjac Borislav , Radeka Ilija , Jockovic Milan , Jeromela-Marjanovic Ana , Miladinovic Dragana , Miklic Vladimir
Published: May 2019

Bearing in mind that the sunflower production in Serbia is extensive, it is
very important to select a hybrid that will achieve stable and high seed and
oil yields in different enviromental conditions. The objective of the study
was to identify the most stable sunflower hybrids for seed and oil yield
using AMMI model analysis. Nine newly developed early, medium early and
medium late hybrids were tested. Hybrids were grown in different locations
across Northern Serbia during two growing seasons (2013-2014). Selected
locations are geographically close, but environmentally different in terms
of soil, rainfalls and temperature, thus creating a specific microclimate
conditions for sunflower growing. Pooled analysis of variance for seed and
oil yield showed that the main effects of hybrids, environments and their
interaction were highly significant. The agro-ecological environment E3 is
most favourable for achieving high seed and oil yields, but E9 was the most
stable. According to results of AMMI model, the most stable hybrids for the
seed and oil yield, i.e. the lowest interaction with the enviroment, were
NS2, NS8 and NS9. The obtained results indicate that hybrids can be
recommended for production in different environments in Serbia; NS2 hybrid
as early-growing, stable for oil yield; NS8 and NS9, medium-late hybrids,
high productivity potential and suitable for all production systems.
Study of genetic diversity of Iranian indigenous buffalo populations using microsatellite markers
Authors: Yousefi Darestani , Miraei Ashtiani , Sadeghi Mostafa
Published: May 2019

Indigenous buffalo breeds represent a unique genetic resource, and
understanding their variability, population structure and breeding units is
important for their sustainable conservation. In the present study the
genetic structure of Iranian buffalo populations was analyzed using ten
microsatellite markers. Two hundred hair samples were collected and DNA was
extracted using modified salting out method. After Polymerase Chain Reaction
(PCR), the PCR products were electrophoresed using 9% polyacrylamide gel.
Fifty- nine alleles were observed for all the loci. The average number of
alleles was 5.90 and the effective average number of alleles was 4.86. The
high level of mean heterozygosity index between three populations indicate
that the genetic diversity is high in within and between populations. The
mean of polymorphism information content (PIC) value for all loci was 0.70.
The FST value for the total loci was 0.01, indicating a very low level of
genetic structure among populations. The genetic structure AMOVA analysis
showed that about 3% of the total genetic variation was explained by
population differences and 97 percent was corresponded to differences among
individuals. The obtained results at the present study indicated that
characterization of genetic diversity by employing molecular tools is a
prerequisite in developing strategies for conservation and utilization of
buffalo genetic resources.
Genetic analysis of spike length in wheat
Authors: Mladenov Velimir , Dimitrijevic Miodrag , Petrovic Sofija , Bocanski Jan , Banjac Borislav , Kondic-Spika Ankica , Trkulja Dragana
Published: May 2019

The permanent need for efficient plant breeding comes from the increment of
human population, which is projected to reach 9.7 million by 2050. Novel
approaches could be used to reach these goals more rapidly, raising the
question of efficiency, as well. Spike length is one of the important
components of grain yield formation in wheat. The influence of individual
plan traits is getting more important to grain yield formation per area unit
in stressful growing conditions, which are increasingly present due to
global climate changes. The objectives of the present research were
three-fold: (i) to determine the influence of a genotype, environment and
their interaction on spike length and to evaluate stability of the trait;
(ii) to present cause-causing links on a graphical example; (iii) to
transform a number of possibly correlated variables into a smaller number of
uncorrelated variables called principal components. Samples were obtained
from 96 winter wheat cultivars grown in 2011/12 and 2012/13 on two
locations. The wheat genotype population was profiled with 28
microsatellites. The ANOVA of the total phenotypic variation of the
experiment shows that genotypes took the largest portion, followed by the
influence of the GE interaction. Additional analysis of the GE interaction
using the PCA analysis shows a statistical significance of the first two
main components. In the conducted research, the dispersion of the points
represents two subpopulations, but the geographical origin could not explain
the grouping of genotypes within the same, so the division into two groups
was done on the basis of their lines of descent.
Expression and function analysis of wheat expasin genes EXPA2 and EXPB1
Authors: Zhu Dong , Liu Yanlin , Jin Man , Chen Guanxing , Prodanovic Slaven , Yan Yueming
Published: May 2019

Expansins are a group of plant cell wall loosening proteins that play
important roles in plant growth and development. In this study, we performed
the first study on the molecular characterization, transcriptional
expression and functional properties of two wheat expansin genes TaEXPA2 and
TaEXPB1. The results indicated that TaEXPA2 and TaEXPB1 genes had typical
structural features of plant expansin gene family. As a member of
?-expansins, TaEXPA2 is closely related to rice OsEXPA17 while the ?-
expansin member TaEXPB1 has closely phylogenetic relationships with rice
OsEXPAB4. The genetic transformation to Arabidopsis showed that both TaEXPA2
and TaEXPB1 were located in cell wall and highly expressed in roots, leaves
and seeds. Overexpression of TaEXPA2 and TaEXPB1 genes showed similar
functions, causing rapid root elongation, early bolting, and increases in
leaves number, rosette diameter and stems length. These results demonstrated
that wheat expansin genes TaEXPA1 and TaEXPB2 can enhance plant growth and
development.
Polarity Protein AF6 Controls Hepatic Glucose Homeostasis and Insulin Sensitivity by Modulating IRS1/AKT Insulin Pathway in an SHP2-Dependent Manner
Authors: Dai Cheng , Wang Xinyu , Wu Yanjun , Xu Yi , Zhuo Shu , Qi Meiyan , Ji Weiwei , Zhan Lixing
Published: May 2019

Insulin resistance is a major contributing factor in the development of metabolic disease. Although numerous functions of the polarity protein AF6 (afadin and MLLT4) have been identified, a direct effect on insulin sensitivity has not been previously described. We show that AF6 is elevated in the liver tissues of dietary and genetic mouse models of diabetes. We generated liver-specific AF6 knockout mice and show that these animals exhibit enhanced insulin sensitivity and liver glycogen storage, whereas overexpression of AF6 in wild-type mice by adenovirus-expressing AF6 led to the opposite phenotype. Similar observations were obtained from in vitro studies. In addition, we discovered that AF6 directly regulates IRS1/AKT kinase-mediated insulin signaling through its interaction with Src homology 2 domain-containing phosphatase 2 (SHP2) and its regulation of SHP2’s tyrosine phosphatase activity. Finally, we show that knockdown of hepatic AF6 ameliorates hyperglycemia and insulin resistance in high-fat diet–fed or db/db diabetic mice. These results demonstrate a novel function for hepatic AF6 in the regulation of insulin sensitivity, providing important insights about the metabolic role of AF6.
NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP)
Authors: Kaestner Klaus H. , Powers Alvin C. , Naji Ali ,   HPAP Consortium, Atkinson Mark A.
Published: May 2019

Type 1 diabetes risk can reliably be predicted by markers of autoimmunity, but approaches to prevent or modify the underlying disease process are needed. We posit this void fundamentally results from a limited understanding of immune-islet cell interactions within the pancreas and relevant immune organs, contributions of β-cells to their own demise, and epigenetic predispositions affecting both immune and islet cells. Because biopsy of the human pancreas and pancreatic lymph nodes carries risk and the pancreas begins to autodigest soon after death, detailed cellular and molecular phenotyping of the human type 1 diabetes pancreas is lacking, limiting our understanding of the mechanisms of β-cell loss. To address these challenges, the National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases established the Human Pancreas Analysis Program (HPAP) to procure human type 1 diabetes pancreata for an extensive array of tissue-based, cellular, and epigenetic assays aimed at critical knowledge gaps in our understanding of the local immune attack and loss of β-cells. In this Methodology Review, we describe how HPAP is performing detailed islet and immune cell phenotyping and creating publicly available data sets with the goals of an improved understanding of type 1 diabetes and the development of more effective treatments to prevent or reverse the disease.
Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes
Authors: Winther Signe A. , Øllgaard Jens C. , Tofte Nete , Tarnow Lise , Wang Zeneng , Ahluwalia Tarunveer S. , Jorsal Anders , Theilade Simone , Parving Hans-Henrik , Hansen Tine W. , Hazen Stanley L. , Pedersen Oluf , Rossing Peter
Published: May 2019

OBJECTIVE

Trimethylamine N-oxide (TMAO) is suggested as an independent gut microbiota–derived risk factor for cardiovascular and renal disease. We investigated associations between plasma TMAO concentrations and cardio-renal outcomes in a prospective study of individuals with type 1 diabetes.

RESEARCH DESIGN AND METHODS

Plasma TMAO was measured at baseline in 1,159 individuals with type 1 diabetes (58% male, mean ± SD age 46 ± 13 years). End points were all-cause and cardiovascular mortality, cardiovascular disease (CVD), and renal events tracked from national registries. Associations between TMAO and end points were tested using Cox regression models.

RESULTS

After 15.0 (6.7–19.3) (median [interquartile range]) years of follow-up, we recorded all-cause and cardiovascular mortality (n = 363 and 120, respectively), combined CVD (n = 406), coronary outcome (myocardial infarction and coronary intervention) (n = 163), stroke (n = 115), hospitalization for heart failure (n = 81), and end-stage renal disease (n = 144). In univariate analyses, higher TMAO concentrations were associated with all end points (P ≤ 0.005). Except for stroke and heart failure, all end points remained significantly associated with higher TMAO concentrations after adjustment for conventional cardiovascular risk factors (P ≤ 0.003). After further adjustment for baseline estimated glomerular filtration rate (eGFR), results became insignificant for all end points. TMAO was inversely associated with baseline eGFR (R2 = 0.29; P < 0.001).

CONCLUSIONS

In individuals with type 1 diabetes, higher concentrations of plasma TMAO were associated with mortality, CVD events, and poor renal outcome, independent of conventional risk factors. However, the association became insignificant after further adjustment for baseline eGFR. This could reflect TMAO as a renal function marker or a risk factor for micro- and macrovascular complications mediated through impaired renal function.
Regional Innovation System in Rural Economic Institutional: Empirical Evidence From Semarang, Indonesia
Authors: Kurniati Edy Dwi , Susilowati Indah , Suharno S.
Published: May 2019

This study aims to analyze the factors that influence the innovation capacity of the rural economic institution and its impact on institutional performance.Research was conducted by interviewing 111 managers of rural economic institutions in Semarang regency, Indonesia. Factors of policy and regulation, development of innovation infrastructure, assistance and integration of knowledge were used to analyze the role of the Government and Higher Education in the village innovation system. The institutional management and innovation culture capacity factors were used to analyze the role of rural economic institutions. Policy and regulatory factors, innovation infrastructure, management capacity, assistance capacity, innovation culture and knowledge integration were measured based on the preference of the rural economic institution manager. The qualitative model was examined through an empirical analysis to fulfill the proposed aim of the research.The results of the study showed that: the influential factors on the innovation capacity in rural areas were policy and regulation support, innovation infrastructure, management capacity, innovation culture and knowledge management. Innovation Capacity had a positive impact on institutional performance.The implication of this study highlighted the importance of strengthening institutional and knowledge-based rural economic organizations which was integrated among stakeholders as actors in the rural innovation system.
Uji Aktivitas Antibakteri Ekstrak Etanol Bawang Dayak (Eleutherine palmifolia (L.) Merr) Terhadap Bakteri Staphylococcus aureus
Authors: Warsiti Warsiti , Wardani Sisca Dwikusuma , Ramadhan Ardea Achmad , Yuliani Ratna
Published: May 2019

Staphylococcus aureus is an infectious bacteria with pus because of tissue damage. Infectious diseases caused by S. aureus include wound infections, ulcers, pimples, and impetigo. Dayak onions have the benefit of being antibacterial. This research aims to study the antibacterial activity of ethanolic extract of Dayak onions against  Staphylococcus aureus. The antibacterial study was carried out using the disk diffusion method. Identification of bacteria by Gram staining showed Gram-positive bacteria which can ferment mannitol with the mannitol test. A bacterial sensitivity test was conducted using three antibiotics i.e. cefoxitin 30μg, vancomycin 30μg, and linezolid 30μg. The bacteria was sensitive to all of the three antibiotics, with the inhibitory zone of 23.5 mm; 17 mm and 27.5 mm, respectively. Vancomycin 30μg was used as a positive control, resulted in average diameter of the inhibitory zone of 17.83  2.25 mm, whereas a control solvent DMSO (Dimethyl sulphoxide) did not produce zones. The ethanolic extract of Dayak onion in the concentration of 25%; 50%; 75% and 100% showed the average diameter of inhibitory zones of 8.17  0.29  mm; 10.67  1.44 mm; 10.33  1.53 mm; and 12.33  1.61  mm, respectively
Uji Aktivitas Antijamur Gel Serbuk Lidah Buaya (Aloe vera L.) Berbasis Carbopol 934 Terhadap Candida albicans dan Trichophyton mentagrophytes
Authors: Afifah Hani , Nurwaini Setyo
Published: May 2019

Fungal infections that occur in the skin and nails were caused by fungi such as Candida albicans and Trichophyton mentagrophytes. Aloe vera contains saponins and acemannan that were effective as an antifungal. This study aims to determine the effect of carbopol concentration variation on aloe vera gel to antifungal activity of Candida albicans and Trichophyton mentagrophytes.Aloe vera powder was obtained from freeze drying aloe vera juice which had been frozen. Aloe vera powder was formulated in gel form using carbopol base with concentration 0.5; 1.0; 1.5; and 2.0 %w/w. The aloe vera gel was tested for its physical properties and then tested the antifungal activity using the diffusion method of wells.The result of evaluation of physical properties showed the high concentration of carbopol then pH, viscosity, adhesiveness increased, and spreading capacity decreased. The results of antifungal activity test showed that aloe vera powder had activity on Candida albicans and Trichophyton mentagrophytes with inhibition zone of 15 ± 3 mm and 13 ± 0,5 mm. Aloe vera gel test results with variation of carbopol concentration 0.5; 1.0; 1.5; and 2.0 %w/w did not affect the antifungal activity of Candida albicans and Trichophyton mentagrophytes.
Kinerja Quagga Pada Routing BGP IPv6 Menggunakan Metode Dual Stack
Authors: Kriswantono Andi , Setyanto Arief , Raharjo Suwanto
Published: May 2019

Alamat jaringan yang digunakan saat ini adalah IPv4 (Internet Protocol v4), perkembangan jaringan menuju IoT (Internet of Think) meningkatkan kebutuhan akan alamat IP (Internet Protocol. Solusi terkait masalah IP adalah dengan melakukan migrasi ke alamat IPv6 (Internet Protocol Version 6).Metode transisi IPv4 ke IPv6 menggunakan Dual Stack merupakan metode yang paling baik dan stabil untuk dapat diimplementasikan. Salah satu pertimbangan dari provider penyedia jasa dan jaringan internet dalam melakukan migrasi ke jaringan IPv6 adalah terkait dengan kinerja BGP (Border Gateway Protocol) yang merupakan routing pondasi terbentuknya internet. Hal ini terkait dengan besarnya rute dengan adanya IPv6 yang nantinya mengakibatkan besarnya konsumsi CPU, memori dan lamanya BGP dalam menerima table routing secara penuh (convergence). Salah satu software routing BGP yang popular dan banyak digunakan di jaringan adalah menggunakan Quagga routing. Hasil dari penelitian ini menunjukkan bahwa penggunaan Quagga dalam menangani 10 peer BGP IPv4 dan IPv6 menunjukkan hasil yang baik, router membutuhkan waktu 106,6 second atau kurang lebih 1 menit 7 detik dengan konsumsi CPU maksimal 18,54% dan konsumsi memori 16,45% untuk dapat menerima seluruh table routing.Kata Kunci — Ipv6, Dual Stack, Quagga, BGP routing, convergenceThe current network address is IPv4 (Internet Protocol v4), network development towards IoT (Internet of Think) increases the need for IP addresses (Internet Protocol). The solutions of IP problem are to migrate to IPv6 (Internet Protocol Version 6) addresses. IPv4 to IPv6 transition method using Dual Stack is the best and most stable method to implement. One of the considerations of internet service provider in migrating to IPv6 network is related to BGP (Border Gateway Protocol) performance that is the foundation routing internet connection. This is related to the magnitude of the route with the IPv6 which will result in the amount of CPU consumption, memory and the length of BGP in receiving the full table routing (convergence) One of the popular and widely used BGP routing software on the network is using Quagga routing. The results of this study show that using Quagga in handling 10 BGP IPv4 and IPv6 peers shows good results, the router takes 106.6 seconds or approximately 1 minute 7 seconds with a maximum CPU consumption of 18.54% and memory consumption of 16.45% to be able to accept all routing tables.Keywords— Ipv6, Dual Stack, Quagga, BGP routing, convergence
PERANAN POLRI DALAM PERLINDUNGAN TERHADAP SAKSI DAN KORBAN PADA PROSES PERKARA PIDANA
Authors: Suyoto Suyoto
Published: May 2019

Lahirnya  Undang-Undang  Perlindungan  Saksi  dan  Korban  dianggap sangat penting dalam rangka perlindungan  saksi dan korban terhadap hak- hak individunya. Kedudukan saksi dalam proses perkara pidana menempati posisi kunci.  Posisi penting yang dimiliki oleh saksi dalam proses perkara pidana, maka sudah menjadi kewajiban bagi aparat penegak hukum, khususnya aparat kepolisian untuk memberikan perlindungan saksi dan korban. Perlindungan saksi tersebut merupakan bagian dari tugas pokok lembaga kepolisian dalam rangka memelihara keamanan dan ketertiban (peace and order maintenance) dan penegakan hukum (law enforcement).Undang-undang   perlindungan   saksi  dan  korban  merupakan  karya terbaru   bangsa   dalam   perkembagan    hukum   pidana   Indonesia   yang mengilhami  sebuah  cita-cita  hukum  yang  melindungi  hak  asasi  segenap bangsa Indonesia terutama hak saksi dan korban dalam proses peradilan pidana. Menilik pentingnya saksi sebagaimana ditegaskan dalam ketentuan Pasal 184 – Pasal 185 KUHAP, maka sudah sewajarnya  saksi atau korban dalam upaya penegakan hukum diberikan perlindungan, sehingga dalam memberikan kesaksiannya di depan pengadilan, saksi merasa aman dan bebas dari ancaman / tekanan baik fisik atau psikis terhadap diri dan keluarganya.Sasaran perlindungan yang diberikan Undang-Undang No.13 Tahun 2006, terhadap saksi dan korban diatur dalam Pasal 5 bahwa hak yang diberikan kepada saksi dan/atau korban tindak pidana dalam kasus-kasus tertentu sesuai dengan keputusan Lembaga Perlindungan Saksi dan Korban. Pasal 36 ayat (1) Undang-Undang No.13 Tahun 2006, memberikan mandat kepada Lembaga Perlindungan Saksi dan Korban untuk bekerjasama dengan instansi berwenang lainnya yang terkait. Perlindungan hukum terhadap saksi oleh pihak POLRI dilakukan berdasarkan tugasnya yang diatur dalam ketentuan Pasal 2, Pasal 13 sampai dengan Pasal 15 Undang-Undang Nomor 2 Tahun 2002 tentang Kepolisian Negara Republik Indonesia. Perlindungan hukum diberikan agar saksi dan korban dapat memberikan kesaksian dengan sebaik-baiknya.
TELAAH UNDANG-UNDANG NOMOR 6 TAHUN 2014 TENTANG DESA DALAM MEWUJUDKAN KEDAULATAN PEMERINTAHAN DESA (STUDI KRITIS IMPLEMENTASI KEBIJAKAN NAWA CITA)
Authors: Kasmi’an Kasmi’an , Subarkah Subarkah , Sukresno Sukresno
Published: May 2019

Penelitian ini ingin membahas dan menelaah Undang-Undang Nomor 6 Tahun 2014 tentang Desa yang terkait dengan penerapan nawa cita, khususnya kedaulatan desa dari nawa cita presiden Jokowi-JK. Kedaulatan desa ini erat kaitannya dengan kewenangan atau wewenang yang dimiliki desa. Kewenangan atau wewenang adalah suatu istilah yang biasa digunakan dalam lapangan hukum publik. Adanya kewenangan desa dan belum adanya kejelasan peruntukan dana desa dalam pembagian dana sertastrategi target dan indikator Pembangunan Nasional Indonesia 2014-2019 berdasarkan Visi Misi Presiden Joko Widodo melalui Nawa Cita. Penelitian ini akan membahas tiga permasalahan yaitu apakah UU No. 6 Tahun 2014 tentang Desa berpeluang menciptakan kedaulatan dalam pemerintahan desa, sejauhmana pelaksanaan UU No. 6 Tahun 2014 tentang Desa melalui implementasi kebijakan Nawa Cita Pemerintahan Jokowi, dan problematika yang timbul beserta alternatif penyelesaiannya. Pendekatan yang digunakan dalam penelitian ini dalah yuridis empiris yang mengandung arti pendekatan yang menganalisis hukum bukan sebagai suatu peraturan perundang-undangan yang bersifat normatif saja, tetapi hukum dilihat sebagai gejala perilaku dan pola masyarakat dalam kehidupan, selalu berinteraksi dan berhubungan dengan aspek kemasyarakatan seperti politik, ekonomi, sosial dan budaya. Data primer diperoleh melalui observasi, wawancara dan kuesioner, sedangkan data sekunder dengan interpretasi perundang-undangan.
OPTIMALISASI INTEGRASI KEBIJAKAN PENGGUNAAN SARANA PENAL DAN NON PENAL DALAM UPAYA PENANGGULANGAN TINDAK PIDANA NARKOBA OLEH KEPOLISIAN RESOR DEMAK
Authors: Saroni Saroni , Hidayatullah Hidayatullah , Wibawa Iskandar
Published: May 2019

Peredaran narkoba yang makin beredar luas di kalangan masyarakat Kabupaten Demak, mulai dari orang tua, remaja, bahkan pelajar semakin meresahkan. Hal tersebut membuat Satresnarkoba Polres Demak harus bergerak cepat untuk menanggulanginya. Oleh karena itu, Satresnarkoba Polres Demak menggunakan integrasi kebijakaan penggunaan sarana penal dan non penal. Sarana penal dilakukan melalui jalur hokum pidana, sedangkan sarana non penal dilakukan sebagai pencegahan. Sedangkan integrasi kebijakan dilakukan dengan menggabungkan kedua sarana tersebut.
HAK KERAHASIAAN WARGA BINAAN PEMASYARAKATAN YANG MENGIDAP HIV/AIDS DALAM PROSES PEMBINAAN DI LEMBAGA PEMASYARAKATAN (Kajian Implementasi di Lembaga Pemasyarakatan Kelas IIB Pati)
Authors: Margayanti Diana , Wibawa Iskandar , Hidayatullah Hidayatullah
Published: May 2019

Hak dan Kewajiban merupakan sesuatu yang melekat dan menyatu pada diri hukum. Hak Asasi Manusia (HAM) adalah hak dasar manusia bersifat universal yang harus dihormati. Pasal 57 ayat (1) Undang-undang Republik Indonesia Nomor 36 Tahun 2009 tentang Kesehatan menyebutkan bahwa setiap orang berhak atas rahasia kondisi kesehatan pribadinya yang telah dikemukakan kepada penyelenggara pelayanan kesehatan. Begitu juga untuk Warga Binaan Pemasyarakatan penderita HIV/AIDS yang mana mereka tidak mau membuka status HIV nya maka harus dirahasiakan karena mereka juga punya hak yang sama atas kerahasiaan kondisi kesehatanya dan bagaimana penyeimbangan antara kewajiban merahasiakan kondisi kesehatanya juga menyeimbangkan agar WBP lain terlindungi dalam proses pembinaan di LAPAS.
Consumer Behavior based on APP use for Food and Beverage Consumption
Authors: Hendry Hendry , Chen Rung Ching
Published: May 2019

McDonalds is one of the brands that release the APP on the Smartphone, the APP is called McDonalds McDelivery APP. It suitable for the way of today’s society way of life, where people are busy and don’t want to line and queue in store to buy foods and beverages for too long. People have a freedom to choose and to order through their Smartphone. The mobile APP offers the advantages, it is easy to operate, easy to use, and doesn’t spend a lot of money. In order to understand the consumers behaviour of using APP, this study conduct the descriptive statistical analysis, variance analysis and regression analysis to detect technology acceptance model for perceived usefulness, ease of use, behaviour intention and actual of use. This study conduct the questionnaire through online google forms and obtained 109 valid questionnaires for analysis. We finds that there was no significant effect on degree of the users, and frequencies of using internet. Perceived usefulness and ease of use of behavioural intentions, behavioural intentions and actual of use had significantly difference.
Proverbs as a Means of Crossing Cultural Borders
Authors: Buja Elena
Published: May 2019

“The grass is always greener on the other side of the fence/hill” is an old English proverb which shows that people tend to appreciate more what others have, just by crossing (with their eyes) the border represented by the fence/hill. Though the afore-mentioned proverb is a strong piece of advice against comparing what we possess with what others have, the aim of my paper is exactly that: to compare proverbs belonging to the Romanian culture to those of the Korean one, not for the sake of highlighting the wisdom or beauty of the Romanian over the Korean proverbs or vice versa but rather for identifying similarities and differences in terms of structure, vocabulary, and, above all, meaning, being aware that proverbs are elements of language that best reflect a culture’s beliefs and values. To this aim, 50 Romanian proverbs selected from two memorable Romanian sources (Iordache Golescu’s Proverbe comentate ‘Commented Proverbs’ and Anton Pann’s Proverbele românilor ‘The Romanians’ Proverbs’) will be compared with their Korean counterparts.
Forecasting CEMAC’s foreign exchange reserves in presence of unanticipated changes in oil prices: an interrupted time series modelling
Authors: Assoumou-Ella Giscard
Published: May 2019

The foreign exchange reserves of the Central African Economic and Monetary Community (CEMAC) countries have decreased since the fall of world oil price that began in July 2014. In fact, five of the six of the CEMAC countries are oil producers. Based on interrupted time series modeling, the analysis shows that the unanticipated changes in oil prices immediately led to a decline in the level of their foreign exchange reserves. The trend is also decreasing. The model predicts a continued degradation of these reserves if oil prices remain low. In these conditions, the CEMAC could experience a currency crisis if economic policies implemented in this region do not lead to a return of economic growth.
Safety of Sea Vessels in the Aspect of Model Research
Authors: Mironiuk Waldemar
Published: May 2019

The article presents a modern method of modeling stability and unsinkability of vessels using physical models of warships and merchant ships. Model tests of watercraft are carried out primarily to assess their marine properties in various operational states. The purpose of this research is to create technically useful calculation methods for forecasting the behavior of a vessel at sea in various meteorological conditions. The main role played by model tests and measurements on real objects is the verification of these methods. Both types of experiments are also a source of inspiration for creating new modified mathematical models and accounting methods based on them. These tests can contribute to the improvement of the safety of vessels at sea.
Use of Faultlessness Indicator to Rate Human Reliability in Human – Operating Aircraft System
Authors: Maciejewska Marta , Fuć Paweł , Galant Marta , Kardach Monika
Published: May 2019

In the M–T–E (man – technology – environment) system, human has a main influence on aircraft. In the article focused on M–T relations, which means human – technology, more accurately on a man impact on a plane, which is specify as human factor [3]. The role of human in this system can lead to an accident, caused by human mistake. In this article fa main question is how man effects on maintenance aircraft. To purpose the analysis the research was made with use of technical object – a simulator, which is located in Simulator Research Laboratory in Institute of Combustion Engines and Transport at Poznan University of Technology. The subject of analysis was a correctness of performing procedures, which every pilot is obligated to make before start operation. Based on tabular research result the analysis of chosen area was made.
Analysis of the Electronic Device Exploitation Process – Research Results
Authors: Paś Jacek , Buchla Sławomir
Published: May 2019

The paper presents an analysis of the operation process of the selected electronic device (ED) like tablet type X. The damage of ED is caused by environmental exposure or use contrary to the applicable operating instructions. The damage initiates the process of changing many or one of the usable features of a specific ED. This usually leads to damage, i.e. changes in the properties of components of a specific ED (e.g. touch screen, compact systems, resistors, capacitors, battery cells, etc.). The basic operational indicators of the ED were determined based on the analysis of the type of damage to all devices that were reported to the service center – 2 391 notifications. The research was carried out on the company’s website, and the duration was 15 months from the time of the introduction of the ED to the market.
Analysis of distribution of precipitation duration and amounts in Legnica in the period of 1966–2015
Authors: Jakubczyk Teresa
Published: May 2019

The paper presents the results of analysis of duration of precipitation sequences and the amounts of precipitation in individual sequences in Legnica. The study was aimed at an analysis of potential trends and regularities in atmospheric precipitations over the period of 1966–2015. On their basis a prediction attempt was made for trends in subsequent years. The analysis was made by fitting data to suitable distributions – the Weibull distribution for diurnal sums in sequences and the Pascal distribution for sequence durations, and then by analysing the variation of the particular indices such the mean value, variance and quartiles. The analysis was performed for five six-week periods in a year, from spring to late autumn, analysed in consecutive five-year periods. The trends of the analysed indices, observed over the fifty-year period, are not statistically significant, which indicates stability of precipitation conditions over the last half-century.
Influence of runoff of suspended solids on quality of surface water: Case study of the Szreniawa River
Authors: Kowalczyk Agnieszka , Smoroń Sylwester , Kopacz Marek
Published: May 2019

Research was conducted in selected points of the Szreniawa River basin (area 712 km2) located in the Miechowska Upland and the Proszowice Plateau. In the years 2016–2017 water samples from the Szreniawa River were taken monthly and the concentration of suspended solids was determined by filtration. The concentration of biogenic components NO3-N, NH4-N and PO4-P was determined by a colorimetric method, using an automatic flow analyser. The average concentration of suspended solids ranged from 192 to 390 mg·dm−3 (with minimum values of 5–20 mg·dm−3 and maximum 837–3937 mg·dm−3) at individual points. There was an upward trend between the content of suspended solids and the concentration of biogenic components. An extremely high concentration of suspended solids happened during storm-like precipitation at the end of June 2017 and amounted to 3937.2 mg·dm−3. The concentration of biogenic components was also highest in this period and amounted to 2.50 mg·dm−3 of NO3-N, 0.49 mg·dm−3 of NH4-N and 1.18 mg·dm−3 of PO4-P. At low precipitation the concentration of suspended solids was also low (5.0 mg·dm−3). A similar pattern was observed for the concentration of biogenic components which was 0.39 mg·dm−3 of NO3-N, 0.17 mg·dm−3 of PO4-P and 0.08 mg·dm−3 of NH4-N.