bluuebunny/crossref_metadata_2025 huggingface dataset:
New Limits on Axionic Dark Matter from the Magnetar PSR J1745-2900
Authors: Darling Jeremy
Published: September 2020

Axions are a promising dark matter candidate that were motivated to solve the strong charge-parity problem and that may also address the cosmological matter−antimatter asymmetry. Axion−photon conversion is possible in the presence of the strong magnetic fields, and the photon so produced will have energy equal to the axion mass. Here we report new limits on axionic dark matter obtained from radio spectra of the Galactic Center magnetar PSR J1745−2900. The magnetar has a magnetic field of 1.6 × 1014 G that interacts with a dark matter density 2 × 105 to 2 × 109 times greater than the local dark matter encountered by terrestrial haloscopes, depending on the Galactic dark matter profile. No significant spectral features are detected across 62% of the axion mass range 4.1–165.6 μeV (1–40 GHz). The interpretation of flux limits into limits on the two-photon coupling strength g

aγγ
depends on the magnetospheric conversion model and on the dark matter density at the Galactic Center. For a standard dark matter profile, we exclude axion models with g

aγγ
 > 6–34 ×10−12 GeV−1 with 95% confidence over the mass ranges 4.2–8.4, 8.9–10.0, 12.3–16.4, 18.6–26.9, 33.0–62.1, 70.1–74.3, 78.1–80.7, 105.5–109.6, 111.6–115.2, 126.0–159.3, and 162.5–165.6 μeV. For the maximal dark matter cusp allowed by stellar orbits near Sgr A*, these limits reduce to g

aγγ
 > 6–34 × 10−14 GeV−1, which exclude some theoretical models for masses >33 μeV. Limits may be improved by modeling stimulated axion conversion, by ray-tracing conversion pathways in the magnetar magnetosphere, and by obtaining deeper broad-band observations of the magnetar.
Noms propres et insulte
Authors: Cislaru Georgeta
Published: September 2020

Noms propres et insultes s’opposent tout en restant liés : d’une part, noms ou insultes sont en principe donnés à la deuxième personne, par un tiers, qui exerce ainsi une sorte de pouvoir social ; d’autre part, l’insulte tend à se substituer au nom propre, en s’attaquant à l’identité de la personne visée. En prenant comme lieu d’observation de l’émergence de l’insulte le nom propre, cet article se propose d’observer le rapprochement possible entre les deux et d’interroger sous cet angle les tensions entre catégories sociales et spécificités individuelles. On examinera ici plus particulièrement deux cas de figure : les surnoms donnés, sur l’internet ou dans les discours politico-médiatiques, aux personnalités politiques en détournant leurs noms (du type Naboléon, Ségogol, Sarkokaïne…) et les pseudonymes choisis ou déformés par les internautes. Dans le premier cas, ce qui nous intéresse c’est le potentiel d’insulte in absentia illustrant l’exercice du pouvoir d’un tiers via et sur le nom ; dans le second, il s’agit d’interroger les frontières entre insulte et connivence dans une perspective d’autonomination ou de création lexicale contournant les pratiques de l’exercice du pouvoir par un tiers. Dans les deux cas, on s’intéressera aux mécanismes sémanticodiscursifs permettant d’associer des traits insultants à un nom propre. Car, si les insultes d’une langue ou communauté rendent compte du système de valeurs de ces dernières, il devient intéressant de voir comment ces valeurs tendent à se cristalliser au plus près de l’identité individuelle en la ramenant à des catégories idéologiques plus larges.
Patrimonialisation et territorialisation de la littérature : causes, enjeux et effets
Authors: Melmoux-Montaubin Marie-Françoise
Published: September 2020

La littérature a récemment été inscrite au « patrimoine » avec l’introduction du socle commun des connaissances dans les programmes scolaires entre 2008 et 2012. Favorisée par l’indétermination du concept, son caractère transdisciplinaire, sa dimension consensuelle et les perspectives économiques et commerciales qu’il ouvre, cette patrimonialisation n’est pas sans conséquences sur la littérature. Elle contribue à la désigner comme un objet en péril, menacé de disparition. Surtout, elle la territorialise, la détachant ainsi de l’universalité dont se réclamait le canon. À rebours de la légitimation, la patrimonialisation se joue pour l’essentiel à l’extérieur du champ littéraire, définissant, à côté de la culture savante une sorte de culture populaire orchestrée par un grand récit national.
« Plus immuable et lourd qu’une colonne de diamant ». Leopardi entre la noia et l’otium
Authors: Veronese Cosetta
Published: September 2020

Cette contribution propose une analyse des signifiés et des implications multiples du thème de l’otium chez Leopardi. En considérant surtout les années du Zibaldone — c’est-à-dire 1820 à 1832 — l’article argumente que la réflexion de Leopardi sur le passage de l’Antiquité à la modernité comporte une perte d’intérêt pour la matérialité de l’action et aussi un affaiblissement des passions, des émotions et des désirs. Cette transformation entraîne le passage séculaire de la poésie à la philosophie, du temps de l’imagination au temps de la raison. L’humanité moderne se contente de la paresse, de l’ennui et de la noia (essentiellement le vide de l’existence), et le flâneur en est devenu l’incarnation. Consciente de la futilité des choses, l’humanité a appris à se contenter du transitoire, de l’éphémère de toutes choses et expériences, préfigurant ainsi le modèle de la société du consumérisme.
Synthesis and Luminescence Properties of Rare Earth (Eu, Tb) Complexes of Octanoylphenylalanine
Authors: Zhang Jin Kang , Gerile Naren , Zhang Ying , Bolag Altan
Published: September 2020

Tb (oct-phe)3·H2O and Eu (oct-phe)3·H2O were prepared by chemical reaction in solution. The molecular formula of the complex was determined by elemental analysis and FT-IR. The optical properties of rare earth complexes were further tested by ultraviolet-visible-infrared absorption measurements. The results show that the optical absorption performance is better in the wavelength range of 200-300 nm. The luminescent properties of the rare earth complexes in the wavelength range of 450-750 nm were tested. It was found that the rare earth (Eu, Tb) complexes of octylphenylalanine have good luminescent properties.
Carrier and Transition Metals (M = Nb, Cr and Fe) Doping Effects on Structure and Electronic Structure in Spinel Li4Ti5O12 Compounds
Authors: Sarantuya Lkhagvajav , Tsogbadrakh Namsrai , Sevjidsuren Galsan , Altantsog Pagvajav
Published: September 2020

Spinel Li4Ti5O12 (LTO) is one of the most promising candidate anode material for Li-ion battery (LIB) known, as zero strain material, it has poor intrinsic electronic properties. In order to enhance it, we have investigated effect of doping on electronic conductivity of spinel LTO phase structure. We consider the carrier and transition metal doping effect on structure and electronic structure of spinel LTO. It is shown that the doping can improve the electronic conduction of spinel LTO. Our calculations were based on the projector augmented wave (PAW) method with the generalized gradient approximation (GGA+U+J0) including the Hubbard U parameter for exchange correlation functional within the framework of density functional theory (DFT).
Apparent Digestibility Coefficients of Nutrients in Diets Containing Jatropha curcas seedmeal by Oreochromis niloticus
Authors: Jimoh W.A. , Shittu M.O. , Ayeloja A.A. , Abdulsalami S.A. , Okemakin F.Y.
Published: September 2020

Purpose : Apparent digestibility coefficients of nutrients in Jatropha curcas based diets were evaluated for Nile tilapia (Oreochromis niloticus) using AIA as marker or indicator.Research Method : A total of 225tilapia were acclimatized for a week, weighed and allotted into five dietary treatments; containing 20 and 40% of 5- and 10-minute toasted Jatropha curcas replacing soybean meal in control diets. The diets were isonitrogenous and isolipidic. Each treatment was replicated three times with fifteen fish per replicate. Fish were fed 5% body weight on two equal proportions per day. Acid insoluble ash and digestibility coefficient determinations followed standard established procedures. Findings : The results from the study indicated that the apparent digestibility coefficients of nutrients in control diets were significantly (p<0.05) higher than that test diets containing Jatropha curcas seedmeal. There was a reduction in the apparent digestibility coefficients of nutrients in the diet with increase replacement levels which were significant (p<0.05) at a 10-minute processing time. However, no significant difference (p>0.05) was observed in the apparent digestibility coefficient of nutrients in 5-minute toasted Jatropha up to 40% soybean replacement among the fish fed the diet. So also, the apparent carbohydrate digestibility coefficient of the different test dietary treatments was not statistically different (p>0.05). Originality / Value : It is evident from this study that diets containing Jatropha curcas seedmeal were relatively well digested by Oreochromis niloticus compared with soybean-based diets.
Examination of hepato-renal functions and lipid panel among pregnant women with preeclampsia in Sétif, Algeria
Authors: Bourouba Romyla
Published: September 2020

Preeclampsia (PE) is a multisystem pregnancy disease inflecting maternal, fetal mortality and morbidity. This case-control study aims to determine the biochemical changes in lipid profile, hepatic and renal functions among sixty preeclamptic women compared to sixty age-matching normotensive pregnant women from the Maternity Hospital in Sétif, Algeria. Several biomarkers were collected and have been determined by appropriate kits. Association between various parameters was evaluated using Pearson’s correlation coefficient, with significance at P<0.05. The PE women showed a significant increase in serum aminotransferase, gamma-glutamyl-transferase, alkaline phosphatase, as well as total cholesterol, triglycerides, urea, uric acid, and creatinine levels. However, a significant decrease in platelets, total protein, albumin, and plasma sodium levels were found in PE group. A positive correlation between aminotransferases and renal biomarkers was observed.PE has deleterious effects on liver and renal functions, and could be predicted by evaluating hepatic and renal biomarkers as well as lipid profile in the early stage of disease, for targeted prevention strategies in our population. Further studies on genetic assessment in cases of PE are needed for a better understanding of this disease’s pathophysiology in Algeria.
Women’s perception and satisfaction with the quality of antenatal care services in mission hospitals in Benin City, Nigeria
Authors: Okoror Collins Ejakhianghe Maximilian , Enabudoso Ehigha Jude , Okoroh Maryjane Ifeyinwa
Published: September 2020

Despite the vital role and availability of antenatal care, only a small proportion of Nigerian women utilise it. Women’s perception and satisfaction with antenatal care is believed to improve health outcomes, continuity of care, adherence to treatment, and the relationship with the provider. The aim is to ascertain the women’s perception and satisfaction with the quality of ANC services in mission hospitals in Benin City, Nigeria. This cross-sectional descriptive study was carried out among 405 pregnant women in their third trimester. Data collection was with a pretested interviewer-administered questionnaire and analysis with IBM SPSS Statistics version 21.0. Statistical significance was taken as P value <0.05. The women’s perception of doctors and nurses was good for all domains assessed. Their satisfaction was highest for cleanliness of the facility 336 (83.0%) and lowest for amount paid for delivery services 168 (41.5%). The overall satisfaction for services received was high 337 (83.2%). The religion of the respondents, gestational age at ANC booking, payment for booking, the delivery fee and availability of requisite resources to cater for the women showed statistically significance with the overall satisfaction. However, only religion (AOR = 17.450, 95% CI = 3.364-90.508) and availability of requisite resources (AOR = 4.629, 95% CI = 2.426-8.832) independently influenced their satisfaction. This study showed a high level of satisfaction with the services rendered. However, making services more affordable as well as improving their quality through investment in both human and material resources to deliver essential care to all clients will drive better satisfaction among them.
Removal of Radioactive Cesium in Secondary Wastewater after Soil-washing Process
Authors: Lee Juhyeok , Kang Jaeeun , Kim Won-Seok
Published: September 2020

Objectives : Secondary wastewater is generated as the soil washing process proceeds to restore contaminated soil near the nuclear power plants (NPPs). In this study, we tried to evaluate the possibility of removing radioactive cesium from secondary wastewater through the adsorption process using illite.Methods : To treat radioactive cesium present in wastewater, as an adsorbent, we used illite collected from Yeongdong, Chungbuk, and weathering illite artificially weathered by high temperature and acid treatment (60℃, 0.01 M HCl). Before and after weathering, the adsorption rate of illite at low concentrations of cesium and the desorption rate of adsorbents were compared and evaluated using a 1.5 ppm of competitive potassium ion similar to that of groundwater.Results and Discussion : When the illite was artificially weathered, the amount of frayed edge sites increased as the interlayer ions in the illite eluted. As a result of the adsorption and desorption experiments, it was confirmed that the adsorption rate of weathering illite increased by about 11% in acid condition (pH 3) and about 26% in neutral condition (pH 6.2), and the desorption rate of weathering illite decreased by about 6% in acid and neutral conditions, compared to Yeongdong illite. Yeongdong illite and weathering illite showed higher adsorption rate under neutral condition than acidic condition, because the surface of the illite became negatively charged at high pH so the reactivity with cesium present as a cation increased.Conclusions : The artificial weathering process has improved the performance of illite as an adsorbent. We expect that weathering illite can be used as an effective adsorbent for the removal of radioactive cesium from NPP.
Health-System Introductory Pharmacy Practice Experience as an online course in the United States
Authors: Kawaguchi-Suzuki M , Merlo J. , White S. , Gibbard R. , Ly L. , Bzowyckyj A. , Bojorquez D. , Begert J. , Saito E. , Marcus K.
Published: September 2020

Introductory Pharmacy Practice Experiences (IPPEs) provide early experiential education in the Doctor of Pharmacy (Pharm.D.) curriculum in the United States (US). In response to Oregon's ‘Stay Home, Save Lives’ executive order issued during the COVID-19 pandemic, an online health-system IPPE course was developed to simulate the practice experiences that have historically been conducted in person. This case study describes experience from the online health-system IPPE course offered for incoming second-year student pharmacists enrolled in a three-year Pharm.D. programme at Pacific University in Oregon, US. The goals of the course were: 1) to expose students to pharmacy practice common in health-system settings in the US; and 2) for students to earn 50 experiential clock hours through simulation activities.
The online teaching and learning experience for pharmacoinformatics during COVID-19
Authors: Sha'aban A. , Zainal H. , Noor D.A.M.
Published: September 2020

At the Universiti Sains Malaysia (USM), Pharmacoinformatics is a second- year undergraduate Bachelor of Pharmaceutical Sciences course designed to introduce students on how to use technology to improve pharmaceutical care services. Until the outbreak of COVID-19, teaching, learning, and assessments for this course were predominantly conducted face-to-face. The unannounced arrival of the pandemic with its unprecedented uncertainties meant a drastic change in programme delivery was necessary. Social distancing and movement control orders were imposed to control the transmission of COVID-19 and hence a complete shift to online learning was required. All available tools were therefore deployed to make the transition a successful experience for both students and lecturers. The advantage of the new learning approach was that both synchronous and asynchronous learning experiences were explored. The group assignments were mostly synchronous using video conferencing applications. However, student assessments by the lecturers were predominantly asynchronous.
Adaptation of laboratory practices in a pharmacology course at a public university in Peru
Authors: Campos-Florián J. , Mantilla-Rodríguez E. , Ybáñez-Julca R. , Quispe-Diaz I.
Published: September 2020

The focus of this case study is the implementation of a pedagogical strategy to adapt the laboratory practices of the Pharmacology course in a Peruvian public university, where animals such as rats and mice are routinely used. Amid the COVID-19 pandemic, and the consequent virtualisation of the teaching-learning process, several academic challenges were posed. The ‘Practical Seminars’ have arisen as a pedagogical proposal that allows faculty to adapt to the conditions of society. They are designed based on selected articles that reflect experiments with drugs, where selected information is adapted, such as graphs, images and even videos. By posing analysis questions allows for students’ previous knowledge to be checked; thus promoting an applied critical attitude to clinical situations. With this resource the faculty tried to recreate a significant space for self-learning. The results of students’ partial evaluation reflects a performance similar to that of previous years of the course, with teaching staff accepting this modality well. Finally, a space for analysis was generated, in addition to dispensing with the use of experimental animals.
The accelerated use of online learning during the COVID-19 pandemic
Authors: Tjahjono D.H. , Anggadiredja K. , Singgih M.
Published: September 2020

Most higher education institutions were not ready for online learning in the early days of the COVID-19 pandemic. The School of Pharmacy Bandung Institute of Technology usually ran online learning for no more than 5% of the total courses (subjects) offered to students. The pandemic has forced learning activities to be delivered online for almost all subjects. For the next semester (autumn 2020) facilities and teaching materials for online learning need to be improved to satisfy stake holders, and to reach equal learning outcomes for students.
Gödel spacetime and Lanczos potential
Authors: Lam-Estrada P. , López-Bonilla J. , Caicedo-Ortiz H. E.
Published: September 2020

We exhibit that, in Gödel geometry, the Lanczos generator can be written algebraically in terms of the Weyl tensor.
Konsep Pendidikan Multikultural Perspektif Al-Qur'an Surah Al-Baqarah Ayat 213
Authors: Ismail Shalahudin , Zahrudin Mamun , Ruswandi Uus , Hadiana Eri
Published: September 2020

Al-Qur’an sebagai petunjuk yang universal berisi pedoman dan pokok-pokok peraturan yang sangat dibutuhkan manusia untuk mengatur kehidupannya, baik yang berhubungan dengan keimanan, maupun peraturan-peraturan yang mengatur tingkah laku dan tata cara hidup manusia baik secara personal maupun komunal. Tujuan penelitian ini adalah untuk mengkaji mengenai konsep pendidikan multikultural yang terdapat dalam al-Qur’an surah al-Baqoroh ayat 213. Adapun metode yang digunakan adalah studi pustaka (library research) dengan menggunakan metode deskriptif kualitatif serta dengan pendekatan tafsir maudhu‟i (tematik). Dari sekian banyak petunjuk yang terdapat dalam al-Qur’an, terdapat dalam surah al-Baqoroh ayat 213 yang berisi nilai-nilai pendidikan multikulturan antara lain; mau belajar dalam perbedaan, kebebasan dalam berpendapat, serta memiliki sifat saling menghargai dan menghormati.
Community Based Cross- Sectional Study to Assess the Utilization Pattern of Antenatal Health Care Services among Married Women of Reproductive Age Group in a Rural Area of Bihar
Authors: Arvind Kumar Vimal  , Pankaj Kumar
Published: September 2020

Background: ANC services is important to ensure safe motherhood. The present study was conducted to assess the utilization of ANC services in rural area.Subjects and Methods:The present study was community based cross-sectional in nature conducted upon 180 currently married women having children of less than one year of age and living in the area covered by rural training center of the institute. Sociodemographic profile and details of utilization of ANC services were noted.Results:Most of the respondents belonged to the age group of 20-30 years. 37.2% of them were illiterate and 58.9% lived in nuclear family. 53.9% had institutional delivery and 42.2% had more than two children. 42.8% of mothers registered their pregnancy before 12 weeks. Only 17.2% mothers had four or more ANC visits. 87.2% of them were fully immunized against tetanus but only 11.1% consumed 100 or more IFA tablets. Lack of awareness was responsible in 28.2%, lack of transport in 16.8%, unwillingness in 34.2% and other reasons in 20.8% cases among the mothers not utilizing ANC services properly.Conclusion: Utilization of ANC services is poor in this area.
Factors Affecting Clinical Outcome of Patients with Traumatic Brain Injury
Authors: Deepali Rishi Rajpal  , Sachna Pramod Shetty  , Manhar Shah
Published: September 2020

Background: The present study aims to describe the severity of injury [Glasgow Coma Scale (GCS)] and outcome of patients [Glasgow Outcome Scale (GOS)] who presented to our hospital with TBI and factors which affect the clinical outcome.Subjects and Methods:All patients, aged equal to or more than 18 years, presenting to the Emergency Department of our hospital due to head trauma during the study period were examined and assessed using GCS at the time of admission, and GOS at the time of discharge.Results:The most common mode of injury was road traffic accident (48%). At the time of admission, 47% had GCS of 13 to 15, 37% had GCS of 9 to 12 and 16% had GCS of 3 to 8. At the time of discharge, we found that 18 patients had GOS of 1, no patient had GOS of 2, 14 patients had GOS Of 3, 28 had GOS of 4 and 29 had GOS of 5. We found that age of the patients was significantly associated with the GOS severity (p value <0.05). Furthermore, GCS at admission was found to be significantly associated with GOS at discharge (p value <0.01). Midline shift on CT head, effaced basal cistern, and presence of subarachnoid haemorrhage were also found to be significantly associated with poor GOS at discharge.Conclusion: The results of our study may be used for stratification of patients, and developing prognostic models to improve the clinical outcome of head injury.
Unilateral Versus Bilateral Frontalis Suspension Sling Surgery for Correction of Severe Unilateral Congenital Ptosis.
Authors: Jyoti Dhaka  , Ashok Kumar Grover
Published: September 2020

Background: To compare the surgical outcome of unilateral silicone sling with bilateral fascia latafrontalis suspension surgery for severe unilateral congenital ptosis.Subjects and Methods:This prospective, interventional and comparative study examined 30 patients of severe unilateral congenital ptosis. 30 patients were divided in to 2 groups, group 1 included 15 patients who underwent unilateral silicone sling frontalis suspension surgery and group 2 included 15 patients who underwent contralateral levator excision with bilateral fascia latafrontalis sling surgery.Results:Mean improvement in MRD1 after surgery in group 1 who underwent unilateral silicone sling surgery was 3.9+1.18 mm and in group 2 who underwent bilateral fascia lata it was 4.9+0.89 mm (p value 0.0001). Excellent results (difference of lid height <1 mm) were seen in 93.3% patients who underwent bilateral fascia latafrontalis sling while in 73.3% patients of unilateral silicone sling. All patients who underwent bilateral fascia lata showed excellent lid crease (symmetric without obliteration) and 80% of the patients who underwent unilateral silicone sling surgery (p value 0.032).Conclusion: Functional and cosmetic outcomes regarding MRD1, symmetry of lid height, lid crease were noted better in group 2 patients who underwent contralateral levator excision with bilateral fascia latafrontalis suspension surgery as compared to group 1 patients who underwent unilateral silicone sling surgery.
Prevalence of Primary Open Angle Glaucoma in Patients with Hypertension
Authors: Archana Pushpakaran  , Sedhu P.A  , Ashwati Sankar  , Cyriac Kurien
Published: September 2020

Background: Glaucoma is the second most common cause of blindness worldwide. It is one of the leading causes of irreversible blindness in the adult population worldwide.Glaucoma is a progressive optic neuropathy. The present study was conducted to assess prevalence of primary open angle glaucoma in patients with hypertension.Subjects and Methods:This cross- sectional study was conducted in outpatient department of SreeNarayana Institute of Medical Sciences. A total of 100 patients with hypertension were included in the study. Prevalence of primary open angle glaucoma in patients with HTN was recorded.Results:Out of 100,59 were males and 41 were females. Among the 100 hypertensive patients, 5% of patients had POAG. Among POAG, 3 were males and 2 were females. The percentage of patients with IOP between 8-21 was 95%, I0P >21 was 5% in right eye. The percentage of patients with IOP in between 8-21 was 95%, IOP >21 was 5% in left eye.Conclusion:High myopia, hypertension, diabetes mellitus has been associated with POAG, however, direct and convincing evidences are still lacking.
Comparative Study to Evaluate Efficacy & Cost Effectiveness of Olmesartanversus Telmisartan, In Patients of Stage I Hypertension
Authors: Pankaj Kumar Singh  , Sameer Kumar
Published: September 2020

Background: Hypertension is one of the most common diseases in the world. It is an important and independent risk factor for atherosclerosis, heart failure, renal disease, and peripheral arterial disease. It is directly responsible for 57% of all stroke deaths and 42% of coronary heart disease deaths in India. Aims and Objectives: To evaluate and compare efficacy and cost effectiveness in hypertensive patients receiving Olmesartan and Telmisartan in Stage I hypertensionSubjects and Methods:The present study was an open, prospective, randomized, parallel group comparative study conducted in 60 patients of stage I hypertension over a period of 16 weeks. Patients were randomly allocated to two, age and sex, matched groups of 30 patients each. Group I patients were started on Olmesartan at a dose of 20 mg & Group II patients were put on Telmisartan at a dose of 40 mg. The BP lowering efficacy and cost effective analysis of Olmesartan versus Telmisartan was calculated & compared. The data was entered in Microsoft excel and compiled. Statistical analysis was done using various tests.Results:Maximum patients in both the groups were in age group of 51-60 years. In group I there were 13 males and 17 females. In group II there were 14 males and 16 females. Both Olmesartan and Telmisartan are effective in lowering systolic & diastolic BP in supine & sitting positions & mean BP is also lowerer, more in Olmesartan group. By cost effective analysis Telmisartan was found more cost effective. Incremental cost effective ratio was found to be 218.35.Conclusion: Both Olmesartan and Telmisartan belong to the same antihypertensive drug class, effectively reduce systolic and diastolic blood pressure at various visits. Taking into account Total cost Telmisartan was more cost effective than Olmesartan. ICER was found to be 218.35.
Impact of Smoking and Diabetes Mellitus on Clinico-Bacterio-Radiological Profile of Pulmonary Koch’s Patients
Authors: Surinder Pal Singh  , Kailash Meena  , Chungath Jain
Published: September 2020

Background: Both smoking and diabetes are attributed to be strongly linked with pulmonary tuberculosis. The significance of the study lies in assessing severity of manifestations in pulmonary tuberculosis patients due to smoking and diabetes. Subjects and Methods:This is a cross sectional observational study among patients presenting to Department of Tuberculosis and Chest Diseases, Government Medical College, Patiala.  200 Patients were enrolled in this study who are sputum smear positive pulmonary kochs patients already on ATT and admitted in this department were evaluated by clinical history, blood and radiological investigations and the data was statistically analyzed.Results:Non smoker non diabetic group had maximum of females, n=28(56%), whereas purely diabetic study group has maximum of males, n=30(60%).The total number of patients whose sputum showed bacterial culture was 19 (9.5%). In the patients having both diabetes and smoking as risk factor there was maximum culture positivity, n=6 (31.5%)and most common organism isolated was klebsiella pneumonia, n=3 (50%), Klebsiella was also the most common organism isolated overall, n=10 (62.5%).Conclusion: The combination of smoking and diabetes can lead to serious disease, sputum positivity and complications.
To Compare Neutrophil Lymphocyte Ratio with Other Parameters in Acute Exacerbation of COPD and Stable COPD: A Hospital Based Study
Authors: Kailash Sharma  , Gajendra Singh  , Ummed Singh
Published: September 2020

Background: White blood cell (WBC) count and its subtypes are also well known systemic inflammatory markers. The ratio of neutrophils to lymphocytes (NLR), which is calculated from complete blood count with differential, is an inexpensive widely available marker of inflammation. The aim of this study to compared the neutrophil lymphocyte ratio with other parameters in acute exacerbation of COPD and stable COPD.Subjects and Methods:A Hospital based comparative study done on 50 Patients with COPD (stable/ exacerbation) attending at Government Medical College, Bharatpur, Rajasthan. While the upper limit of neutrophils count for normal range was set at 8x109/l, the lower limit of lymphocyte count for the normal range was set at 0.9x109/l. NLR was calculated as the ratio of neutrophils to lymphocytes, both of which were obtained from the same automated blood samples for the study.Results:Our study showed that the comparison of mean value of age, BMI & pack years was statistically significant (P=0.0112, P<0.0001 & P=0.0141 respectively) in between groups. The comparison of mean value of NLR was statistical significant (P=0.0009) in between groups. NLR measurement demonstrated a sensitivity and specificity of 40%and 77.14%. PPV and NPV for NLR were 63.64%and 56.25%, and OR and RR were 2.250 and 1.455. A positive correlation was determined between NLR and CRP (r=0.482; p<0.05).Conclusion: NLR, like CRP, both readily available and simple parameters, could also be used as a cost-effective marker of inflammation in AECOPD.
Study of Histopathological Patterns in Breast Lumps
Authors: Shalini Kashyap  , Sachin Chauhan
Published: September 2020

Background: Breast lesions in females are heterogeneous diseases that consist of several distinct entities with remarkably different characteristic features. The present study was conducted to assess histopathological findings of excision biopsies of breast lesions.Subjects and Methods:The present study was conducted on 150 cases of lumpectomy breast specimens received in the department of histopathology. The histopathological diagnosis made after routine processing and hematoxlin and eosin staining.Results:The most common age group of presentation was 30 to 50 years having well defined breast mass lesion. The difference was significant (P< 0.05). Among 150 breast specimens, 145 found to be benign and 05 malignant. In benign, common lesions were fibroadenoma in 64, fibroadenosis in 30, Acute Suppurativeinflammatory lesion (Abscess) in 20, fibrocystic disease (FCD) in 22, duct papilloma in 05 and benign phyllodes in 04 cases. In malignant, 04 cases were infiltrative ductal cell carcinoma NOS (Not otherwise specified) and 01 carcinoma in situ. The difference was significant (P< 0.05).Conclusion: Authors found that most common benign breast lesions were fibroadenoma (44.1%) and fibroadenosis (20.6%) followed by acute suppurative inflammatory (Abscess) and  FCD.
Cytomorphological Assessment of FNAC Findings of Thyroid Swellings
Authors: Shalini Kashyap  , Anil Kumar Gupta
Published: September 2020

Background: There is enormous burden of thyroid diseases in the general population. Among all the endocrine disorders, thyroid disorders are the most common in India. The present study was conducted to assess FNAC findings of thyroid swellings. Subjects and Methods: The present study was conducted on 108 patients with thyroid swellings. A thorough clinical examination was performed. USG findings were recorded in the available patients. FNAC was done as per standard protocols. Results: Out of 108 cases, males were 32 and females were 76. Common thyroid swelling was colloid nodular/adenomatous goitre seen in 57 patients followed by Lymphocytic Thyroiditis in 17 patients, simple colloid cyst in 12 patients, follicular neoplasm in 10 patients, toxic goiter (grave's disease) and papillary carcinoma in 03 patients each with insufficient material obtained  in 06 patients. The difference was significant (P< 0.05). Conclusion: Authors found that most common thyroid swelling was colloid nodular/adenomatous goitrefollowed by lymphocytic thyroiditis with sensitivity of FNAC found to be 73.5%.
Malignant Melanoma of Small Bowel: A Rare Case
Authors: Kamal Bandhate  , Ashok Kumar Diwan  , Subeera Khan
Published: September 2020

Melanomas affecting the small bowel are usually metastasis from primary cutaneous lesions. A primary melanoma of the gastrointestinal tract is very rare with reported incidence of just 3%. We present a case of small bowel melanoma with liver metastases. Primary malignant melanoma of the small intestine is quite rare with only a few cases reported in literature. Like its cutaneous counterpart, intestinal melanomas too remains an aggressive disease with a poor prognosis. The overall survival of malignant melanoma affecting the GI tract is 4 to 6 months with a survival rate of less than 10% at 5 years.
Resolution of Post-Molar Pregnancy Uterine Arteriovenous Malformation Following Treatment with GnRH Agonist Concomitantly with an Aromatase Inhibitor and Tranexamic Acid
Authors: Vilos Angelos G. , Haakman Olga , Liang Tina , Alzawawi Nabigah , Lam Jennifer , Abu-Rafea Basim , A. Vilos George , Vilos Angelos G.
Published: September 2020

Background: Acquired uterine arteriovenous malformations (AVM) are a rare but potentially serious
condition that can result in severe bleeding. Rarely, uterine AVM can occur following a complete molar
pregnancy. Resolution of AVMs has been reported recently with conservative management using a
combination of Gonadotropin-Releasing Hormone (GnRH) agonist, an aromatase inhibitor and tranexamic
acid. This treatment has not previously been reported in a patient with AVM post molar gestation. Case
Presentation: A 23-year-old woman was diagnosed with a large uterine arteriovenous malformation
following a suction curettage for a molar pregnancy. Complete resolution of the lesion on imaging was seen
after six weeks of medical management. Conclusion: A uterine arteriovenous malformation can develop in
a patient post complete molar pregnancy and can be successfully treated with medical management.
Cutaneous Mucormycosis: Case Report
Authors: Korem Maya , Ayalon Oshrat , Ibrahim Ruba , Neumark Michal , Korem Maya
Published: September 2020

Treatment with 5-FU cream, an antimitotic agent, is primarily used for the treatment of superficial
keratinocytic lesions. This treatment modality has the potential to cause severe localized inflammation with
subsequent erythema, pain and crusted erosions. Cutaneous mucormycosis is an opportunistic emerging
fungal infection. It is rapidly progressive and affects immunosuppressed or poorly controlled diabetic
patients primarily by direct inoculation or secondarily by dissemination. The clinical presentation can be
challenging due to its initial nonspecific features and therefore leading to a delay in the diagnosis. Herein,
we report a case of mucormycosis of the scalp following treatment with topical 5-FU.
Assessment of University Students’ attitude towards Fast food consumption Based on the Prototype/Willingness model: A Qualitative Study in the East South of Iran, Rafsanjan
Authors: Mahbobi Rad Mahmood , Mazloomy Mahmoodabad Seyed Saeed , Asadpoor Mohammad , Vaezi Aliakbar , Fallahzadeh Hossien , Zareei Mahmoodabadi Hassan
Published: September 2020

Background and Purpose: University students are young and are thus at a critical period of adopting healthy behaviors. Their life-style exposes them to a high rate of consuming fast food. In the long run, they are faced with higher chances of obesity and risk of affliction with diabetes and cardiovascular diseases. The present research aims to explore university students’ attitude towards fast food consumption based in the Prototype/Willingness model. Materials and methods: The present research followed a qualitative approach and a directed content analysis in 2018-19 among students affiliated with Rafsanjan universities. The participants were selected through purposeful sampling. A semi-structured interview was held with 20 students and it went on until data satiation occurred. The qualitative content analysis was done through Graneheim and Lundman method. Results: Analysis of university students’ experience of fast food consumption led to the extraction of 2 categories, 16 sub-categories and 65 final codes. The main theme was attitude for which the following subcategories were extracted: pleasure in consumption, fast preparation, inability to cook, lethargy, low cost, inadequate monitoring, Indulgence, bringing excuses, lack of knowledge, optimism in one’s health, consumeristic media, disorganized student life. For the negative attitude category, the following sub-categories were considered: attempts to provide healthy food, hated to fast food consumption, creation of a healthy supportive atmosphere by the family, bad experiences, perceived threat and perceived consequences. Conclusion: Knowledge of positive and negative attitudes would help program designers to contrive of the best preventive strategy focused on the adjustment of positive attitudes and reinforcement of negative attitudes to fast food consumption.
Evaluation of Rasayaṇa activity of Rudanti (Capparis moonii Wight.) in the Management of Rajayakshma (Pulmonary tuberculosis)
Authors: Nagar Lalit , Lamo Ringzin , K Mishra J , N Dwivedi K
Published: September 2020

It is estimated that about 1/3rd world’s population is infected by Mycobacterium tuberculosis. It kills more adults in India than any other infectious diseases. In 2018, India was able to achieve a Total Notification of 21.5 Lakh TB cases of which 25 % was from the private sector. Majority of the TB burden is among the working age group. The 89% of TB cases come from the age group of 15-69 years. About 2/3 of the TB cases are Males. Uttar Pradesh, with 17% of population of the country, is the largest contributor to the TB cases in with 20% of the total notifications, accounting to about 4.2 Lakh cases (187 cases/ lakh population). Aim and objective: This study was intended to evaluate the rasayaṇa effect of Rudanti (Capparis moonii wight.) as an adjunct to anti-tubercular drugs in the management of Rajayakshma (PTB). Methodology: This is a single blind therapeutic control randomized clinical trial consisting of 100 patients divided in to two groups. Group A patients were treated with DOTS and group B were treated with DOTS along with Rudanti powder 5 gm BD for 6 months. Conclusion: This study shows that by incorporating an herbal rejuvenative in the management of PTB, a chronic debilitating disorder, had an additive effect. Rudanti powder can be easily administered as an adjunct to DOTS. Rudanti has hepatoprotective properties, which remunerate the hepatotoxicity known to cause by DOTS drugs. Improved weight gain in TG patients in comparison to CG indicates the accessory effect of Rudanti.
Ayurvedic Management of Arditavata - A Case Report
Authors: Mahajan Kusum , N Belavadi S
Published: September 2020

Ayurveda is a branch of ancient science which is not only believe in curing disease but also keeps vision of having healthy lifestyle in terms of Ahara (Food), Vihara (Healthy regimen) and Achara (Good conducts). In present era because of unwholesome food, inappropriate lifestyle, excessive and restless workload etc. and also the environmental factors like excessive cold and flowing of wind becoming reason to cause various disorders. Acharya Charaka explained 80 Vataja Nanatmaja Vyadhi, Arditavata is one of those disorders.Due to similar clinical symptoms of Arditavata, in contemporary science can be correlated with Bell’s palsy-caused by dysfunction of facial nerve-which is VII cranial nerve which affects the movement of facial muscles. Facial nerve dysfunction can seriously influence a patient's perspective for life. The human face is a part of communication and appearance. Facial palsy results in both functional and cosmetic impairments. In this disease with Ayurvedic treatment approach there is 90% cure rate, which is very beneficial for the present era patients who are having such type of diseases. This case study is here to show the result and curative approach of classical medicines in Arditavata.
A Case Study on Management of Rett Syndrome by Wholistic approach
Authors: Rathi Renu , Rathi Bharat , Khatana Rakesh , Sankh Suraj
Published: September 2020

Background: Rett syndrome-RS comes under Autism spectrum disorder-ASD which is a neurodevelopmental syndrome. It is diagnosed by the main differentiating features of lack of interpersonal and communication skills, poor eye contact, delayed speech with pervasive abnormal body movements. Aim and Objectives: This case report is aimed at dissemination of comprehensive role of Ayurveda in management of ASD, Rett syndrome. Material and Methods: RS is the severe form of ASD. This case study of 2.3 year’s girl presented with RS and global delay, being treated with wholistic approach. It comprises Ayurveda chikitsa and other therapies like Yoga, hydrotherapy, occupational, music, physiotherapy and many more. Observation and Result: Patient has shown promising results in all developmental milestones such as gross motor, fine motor and personal social in 6 months duration except language. Different varieties of massage therapy, diet and Basti, Nasya (Panchkarma) procedures, Omkar mantra chanting, passive Yogasana were done. Conclusion: In this case report, mainly Ayurveda interventions were implemented with wholistic approach as an adjuvant, received good result in gross motor development which is very difficult in RS, hence it is a unique case. It also opened the door of wholistic approach with the hope to deliver the good result in similar disorders.
Quantitative Analysis of Medicinal plants used by the Traditional healers of Karanja block of Wardha district for treating Musculoskeletal disorders
Authors: Rathi Bharat , Rathi Renu
Published: September 2020

Background: 20% to30 % elderly population suffers with Musculoskeletal disorders such as Multiple joint pains, Low back pain, Rheumatoid arthritis, Osteoarthritis. Multiple treatment modalities are in vogue to treat MSDs all over the world but neither provides adequate pain relief nor modifies the disease process. Hence majority of the tribal population prefer traditional healers for treating MSDs as they are safe, effective, inexpensive and easily available. Aim & Objectives: Quantitative analysis of Medicinal plants used by the traditional healers of Karanja block of Wardha district for treating musculoskeletal disorders. Material & Methods: The survey study was carried out through field visits. Questionnaire, personal interviews and discussions with the traditional healers were used for data collection. Specific pharmacological properties of herbal drugs used by the traditional healers to treat MSDs were authenticated by taxonomist and forest range officer and verified through Nighantus and Samhitas. Observations & results: Total 17 traditional healers were interviewed for data collection. Total 23 plant species belonging to 20 families were indentified and documented for the treatment of MSDs.  Tribal utilized 9 varieties of plant parts from 4 types of habitat and treat the patients of MSDs with 5 types of medicinal preparations through external and internal applications.
Impact of Junk food on Physical and Mental health of the Youngsters in Bhopal city - A Cross Sectional Survey Study
Authors: Verma Ravi , Bansal Charu , Jain Trupti
Published: September 2020

Background- Ayurveda has given a unique concept of Viruddha Ahara. Junk food an energy-dense food could be consider as Viruddha Ahara because of its serious physical and mental health consequences. Aim - Find out the frequency of consumption of Junk food preparation and their effects on Physical & Mental health in the youngsters of Bhopal city with special reference to Viruddha Ahara. Study Design- was Observational cross sectional study. Material and Method- Modified Questionnaire based on WHO STEPS1, 2 and 3 guidelines was used to collect the data. 600 youngsters of age group between 12-25 years from various schools and colleges of Bhopal city were selected by stratified random sampling technique and Statistical Analysis was done with epi infoTM version 7 software. Appropriate statistical tests were applied such as frequency distribution, cross tabulation (M x N/ 2 x 2 Table), chi square test, z statistics and logistic regression analysis. Odds ratios (OR) with 95% confidence intervals (C.I) and p-value (significant <0.05) were also calculated as per need. Result- It was observed that all subjects were consuming different kinds of junk food with high mean frequency that was 3.28 days per week.  Maximum youngsters were suffering from various physical and mental health consequences like 80.83% subjects were suffering from nutritional problem, 73.50% skin problems, 73.33 % GIT problems and 58.67% had anxiety disorder and 38.50% had recognised with mood disorder. Conclusion: The result of the survey study indicating that serious health consequences are developing in youngsters by consumption of viruddha ahara (Junk Food) and that could be converted them in chronic disease patients in near future.
Management of Chronic Non-Healing Wound using Ayurvedic drugs - A Case Study
Authors: Panigrahi Hemanta Kumar
Published: September 2020

Sushruta in 1st part of his compendium described about wound healing its types etc. as Vranitopasaniya adhyaya. Ayurveda described so many compound medicines and oil for oral administration and topical application to accelerate the wound healing. But this is not scientifically validated. So there is always a search for finding a newer and better medicine for wound healing. I am presenting a case of 42 year old married male with complain of superficial external wound with mild pain,  mal odour  and not healing  since 45 days in spite of taking allopathic conventional treatment in his lower limb. The study was done in my outpatient department of Central Research institute for cardiovascular disease, Punjabi Bagh, New Delhi. On examination it was found that surface area of superficial wound is 22.5 sq. cm. having full thickness, skin loss involving necrosis of subcutaneous tissue extended down to underlying fascia. Necessary laboratory investigations were done prior to initiate the treatment. The wound was irrigated with Panchvalkala kasaya and dressing with Jatyadi Tail was done daily followed by oral intake of Triphala guggulu 500mg twice in a day and Amalaki churna 6gm twice in a day was administered orally for 28th days. Periodic follow up was done on 0, 7, 14, and in 28 days. This regimen was found to be effective in faster wound epithelialization, and reducing wound exudates. There was no evidence of any allergic reaction as well as no evidence showing any adverse event on the wound.