bluuebunny/crossref_metadata_2025 huggingface dataset:
Pix: aceitação e resistência - uma análise sob a perspectiva da Teoria da Resistência à inovação e da UTAUT2
Authors: Felipe Kamila Januário , Martins Luiz Gustavo de Oliveira , Sobral Eryka Fernanda Miranda , De Melo Fagner José Coutinho , Vital Junior Silvio André , Da Cruz Tatyane Veras de Queiroz Ferreira , De Araújo Hérica Gabriela Rodrigues , Guimarães Junior Djalma Silva , Santos Emerson Silva
Published: September 2023

O objetivo dessa pesquisa é identificar os fatores que influenciam na adoção do PIX como meio de pagamento digital pelos consumidores, considerando as perspectivas teóricas da teoria UTAUT2 e da Teoria da Resistência à Inovação na região do Sertão Central de Pernambuco. Para essa finalidade, foi utilizado uma amostra quantitativa em forma de questionário adaptado de Sobral (2020) que avaliou os determinantes de adoção dos meios de pagamento digitais. A amostra considerada para essa análise foi de 87 usuários, sendo realizada uma sondagem do material e estudos já realizados por meio de artigos, revistas e pesquisas para aprofundar-se mais no meio a qual será analisado, buscando saber sobre a adesão do PIX e de pagamentos digitais em outras regiões. A partir de análise de regressão, os resultados sugerem que barreira de uso, barreira de risco e barreira de imagem são fatores que se mostram determinantes na resistência à inovação no uso do PIX na região do Sertão Central de Pernambuco. Ser da zona urbana, da geração Y e Z (pessoas de 13 a 42 anos), motivações hedônicas e expectativa de desempenho influenciam na intenção comportamental do uso do PIX. Por fim, que a intenção comportamental desempenha papel significativo na adoção em si do PIX.
Estimation of Waiting Time and Consultation Duration for Patients in the Outpatient Department of Radiation Oncology at a Tertiary Care Teaching Hospital in Uttarakhand, India: A Cross-sectional Study
Authors: Joshi Dinesh Chandra , Saini Ravinder Singh , Samant Shweta , Bijlwan Sangeeta
Published: September 2023

Introduction: The Outpatient Department (OPD) holds significant relevance in modern medical care and serves as the “Shop Window” of the hospital. Waiting time serves as a crucial indicator of the quality of OPD services provided by the hospital, as it greatly affects patient satisfaction. Radiation oncology is a clinical specialty that focuses on administering radiation therapy to cancer patients, who seek consultation in the radiation oncology OPD. Aim: To estimate the waiting time and consultation duration for patients in the OPD of radiation oncology at a tertiary care teaching hospital. Materials and Methods: This cross-sectional study was conducted from August 1 to August 31, 2022, at the Cancer Research Institute of Himalayan Hospital, which is the affiliated hospital of the Himalayan Institute of Medical Sciences under the aegis of Swami Rama Himalayan University, Dehradun, Uttarakhand, India. A total sample size of 300 patients was selected using the simple random sampling technique. Data was collected through direct observation using a data collection sheet. Statistical analysis was performed using the data analysis tool in Microsoft Excel and Statistical Package for Social Sciences version 23.0. Pearson coefficient of correlation (r) and p-value were calculated. Results: The results were analysed based on demographic details, days of the week, patients seen per consultation room, new and follow-up patients, and patient arrival time in the OPD. The majority of patients attending the OPD were in the age group of 50-69 years (60.6%). A total of 256 patients (85%) were follow-up patients. Analysis of the patient arrival pattern revealed that the highest number of patients, 200 (66.7%), arrived between 8:30 AM and 10:30 AM. The overall mean waiting time was estimated to be 50.43±0.030 minutes, and the mean consultation time was estimated to be 9.53±0.004 minutes. The Pearson coefficient of correlation between the two variables was calculated, revealing a positive correlation with ‘r’ value=0.14 and a statistically significant p-value=0.014 (<0.05). Conclusion: This study provides valuable insights for waiting time and consultation duration in the radiation oncology department's OPD. On average, patients spend approximately 59.96 minutes in the OPD premises. Out of this time, 84.1% is spent waiting, while 15.9% is spent with the consultant. The primary reason for delays in the waiting area is the delayed availability of consultants due to ongoing ward rounds or other academic activities.
Primary (Idiopathic) Non-Pancreatic Retroperitoneal Pseudocyst in a Young Female: A Rare Case Report
Authors: Philip Abhay M , Tauro Leo F
Published: September 2023

Retroperitoneal Cysts (RPC) are uncommon, with an estimated incidence of 1 in 5,750 to 1 in 250,000. A 26-year-old woman presented with dull aching, non-radiating pain in the upper abdomen for the past two months, with no aggravating or relieving factors. On clinical examination of the abdomen, a grossly visible mass measuring approximately 10x10 cm with a smooth surface, firm consistency, and well-defined borders was observed in the left lumbar and iliac region. Contrast-Enhanced Computed Tomography (CECT) of the abdomen and pelvis revealed a well-circumscribed cystic lesion measuring 9.3x9.5x5.5 cm in the left lumbar region near the tail of the pancreas. The pancreas appeared normal with no surrounding fat stranding or inflammatory changes. Peripheral enhancement and peripheral wall calcification were observed. The patient underwent laparotomy and cyst excision. Intraoperatively, the cyst was found to arise from the retroperitoneum located in the lesser sac. It was dissected out from the tail of the pancreas, and no obvious communication with the pancreas was observed. The cyst was excised completely. Histopathological examination revealed a cyst with absent endothelium, suggestive of a pseudocyst. Previous literature reports indicate that RPCs are very rare and are often discovered incidentally. Patients may be asymptomatic or present with vague symptoms. Imaging can help diagnose these lesions, but surgery is crucial in confirming the diagnosis.
Employees’ Compensation Packages and Profitability of Consumer Goods Firms in Nigeria
Authors: Richard Eze Anya, , Inyiama Oliver Ike , Okwo Ifeoma Mary
Published: September 2023

The study examined the effect of wages and salaries, bonuses and incentives, and training costs on the return on capital employed of sampled consumer goods firms in Nigeria. Data were collected from annual financial reports of the firms for the period, 2013-2022. The research adopted an ex-post facto research design. The systematic Sampling technique was used to select a total of four (4) companies for the study. The analytical tool used for the study was ordinary least square multiple regression. Results of the test of hypotheses indicate that Wages and Salaries have a negative but significant effect on Return on Capital Employed. Bonuses and Incentives have a negative and insignificant effect on the Return on Capital Employed however; training Cost has a positive and significant effect on the Return on Capital Employed of consumer goods firms in Nigeria. The study suggests that Wages and salaries should not be higher than the value addition made by the employees and labourers, rewards should be directly related to performance and as wanted by the recipient and Training of staff is very pertinent to a company’s overall success.
Molecular Analysis of Drought Tolerance in Rice Varieties Using SSR Markers
Authors: Antardani Soumya , Dwivedi D. K. , Khan N. A. , Kumar A. , Singh Anoushka , Ritendra  , Pooja  , Devi Archana
Published: September 2023

The objective for this study was to learn about the drought stress of the rice plant. Using the well-distributed simple sequence repeat (SSR) markers RM327, RM206, RM23, and RM1075 identified different rice genotypes. The groups of 20 rice cultivars that were cultivated under stress conditions were identified using SSR-based clustering analysis. Dendrogram demonstrated genotype cluster analysis This indicates that there is significant genetic variability within each group, according to the population structure in UP. Rice, Future coordinated association mapping investigations will be made possible by knowledge of population structure and related phenotypic traits recognised by geneticists and breeders.
Transformative Role of Remote Sensing in Advancing Horticulture: Optimizing Sustainability, Efficiency and Resilience
Authors: Rai Ram Kumar , Karada Makhan Singh , Mishra Riya , Agnihotri Dheer , Patel Kamal Kishor , Thakur Satyendra , Singh Deepak
Published: September 2023

The field of horticulture, vital for addressing global challenges like food security and sustainable agriculture, has been revolutionized by remote sensing technology. This comprehensive review explores the transformative impact of remote sensing on horticulture, emphasizing its role in optimizing resource utilization, promoting environmental sustainability, and mitigating the effects of climate change. Remote sensing, encompassing a range of sensors, satellites, and data analysis techniques, enables the collection of critical information from a distance, providing insights into crop health, soil conditions, water availability, and more. Precision agriculture, including the use of GPS and GIS, is integrated with remote sensing to enhance agricultural efficiency while minimizing environmental impacts. Site-Specific Crop Management (SSCM) is highlighted as a key component of precision agriculture, enabled by geospatial technologies, including remote sensing. It discusses how remote sensing systems, with their multispectral and multi-temporal capabilities, support various horticultural applications such as crop yield estimation, abiotic and biotic stress management, crop classification, canopy measurement, crop area estimation, and even crop insurance validation. The use of Geographic Information Systems (GIS) and the Global Positioning System (GPS) in tandem with remote sensing is explored in the context of spatial analysis, mapping, and precise navigation.
Assessing Barriers to Production and Marketing of Tasar and Mulberry Silkworm Cocoons in Selected Districts of Chhattisgarh, India
Authors: Atree Narottam , Choudhary V. K. , Patel Pradip Kumar , Painkra Amit Kumar , Ram Siya
Published: September 2023

The study conducted “Analysis of constraints on production and marketing of tasar and mulberry silk in Chhattisgarh” included four districts i.e. Bastar, Korba, Jashpur and Raigarh. In each district one block, from Bastar district Jagdalpur block, Jashpur district Kansabel block, Korba district Korba block and Raigarh district, Dharamjaigarh block has been selected for the study based on maximum tasar and mulberry seed centres and 16 villages has been selected for the study, information about the primary data was collected from 160 cocoon growers in selected areas, though well-prepared interview schedule/ questionnaires. The study observed that tasar and mulberry cocoon grower and their marketing was found to be major constraints unavailability of labour during the production process was ranked first according to measurement, respectively silkworm, lack of knowledge in the maintenance of host plant, unavailability of the good quality plantation, lack of technical guidance, unavailability of input on time, difficulty obtaining DFL’s, lack of knowledge about training and pruning of host plant among marketing constraints suffers SHG’s were obtaining rank first lack of marketing facilities, followed by the poor quality of cocoon, difficulties of grading of the cocoon, lack of market information regarding the price of tasar and mulberry cocoon, lack of proper price received by cocoon growers, transportation cost, the lake of proper payment facility to silk grower and lack of storage facilities of cocoon despite all the constraints the area has great potential for silk production. Therefore cocoon growers in the study area can be provided with adequate knowledge in both tasar and mulberry cocoon production to enhance the production and productivity of cocoons.
A Comprehensive Review on Cucurbits Yellow Stunting Disorder Virus (CYSDV) and their Management
Authors: Nagar Badri Lal , Pandey Sakshi , Raghuvanshi Himendra Raj , Muhammad Suhaib Ismayil M.  , Singh Shwetank , Thapliyal Vivek , Kushwaha Dhananjay , Kumar Arun
Published: September 2023

Cucurbit Yellow Stunting Disorder Virus (CYSDV) represents a significant threat to global agriculture, particularly impacting the cultivation of cucurbit crops such as melons, squashes, and cucumbers. This comprehensive review explores the various dimensions of CYSDV, including its taxonomy, epidemiology, pathogenesis, diagnostic methods, management, ongoing research, and the broader social and economic implications. Beginning with an examination of CYSDV's classification and morphology, the review delineates the geographical distribution of the virus, its host range, transmission vectors, and environmental factors influencing its spread. It also outlines the mechanisms of infection, stages of disease development, symptoms in various cucurbit species, and the economic impact of the disease. The discussion extends to both traditional and molecular diagnostic techniques and the associated challenges. Different strategies for managing and controlling CYSDV are highlighted, including cultural practices, chemical methods, biological control, and integrated pest management approaches. The review emphasizes ongoing research initiatives and future perspectives in CYSDV research, considering technological innovations and potential limitations. The final sections focus on the broader social and economic context, exploring the impact of CYSDV on small and large-scale farming, international trade considerations, community engagement, and government initiatives. Through an integrated analysis, this review provides valuable insights into the multifaceted nature of CYSDV, its influence on agriculture, and the wider societal dynamics. The conclusion underscores the necessity of a coordinated, comprehensive approach that leverages scientific research, international collaboration, community involvement, and governmental support to address the challenges posed by CYSDV. Understanding the complexities of this virus is essential for developing effective strategies to ensure food security and economic stability in regions affected by this detrimental plant disease.
Microbial Responses to Carbon Sequestration Soil Amendment and Productivity
Authors: Amulothu D. V. R. T. , Kumar Jogendra , Pal Apurba , Mondal Kabita , Rai Sumit , Maurya C. L. , Yadav Rishikesh , Singh Bal Veer
Published: September 2023

Soil a significant carbon sink, plays a pivotal role in mitigating climate change. This review underscores the potential of soil amendments for enhancing carbon sequestration, focusing on the intricate relationship between these amendments and soil microbial communities. Soil amendments, ranging from biochar and organic compost to mineral additives, have been identified as viable strategies to boost soil carbon stocks. Concurrently, these amendments influence the diversity, structure, and functional roles of microbial communities, which in turn, are integral to soil carbon dynamics. Tools like 16S rRNA sequencing, metagenomics, and isotope tracing techniques have propelled our understanding of microbial responses, shedding light on the complex microbial networks and their roles in carbon cycling. While promising, the application of soil amendments presents challenges. Variability arising from different soil types, climates, and microbial dynamics poses a consistent research challenge. Potential risks like reduced sequestration over time and economic considerations for large-scale application necessitate attention. Future directions hinge on innovations in soil amendment products, harnessing microbial inoculants for synergistic effects, and fostering interdisciplinary collaborations. This convergence of science, technology, and collaborative research heralds a future where soils are not just seen as substrates but as active, dynamic entities in the fight against climate change.
Molecular Characterization of Pongamia pinnata (L.) Pierre Genotypes in Respect to Seed Oil Using Microsatellite Markers
Authors: Kumari Kanchan , Singh Sanjay
Published: September 2023

Twenty-four genotypes selected from different agroclimatic zones of Jharkhand (India) were assessed for seed oil content that varied from 21.86% to 41.86% with 14 genotypes recording above average 32.11 % for the trait which indicates towards efficiency of selection processes. Several genotypes in ‘Central and Western Plateau’ agroclimatic zone of Jharkhand displayed a good potential for high oil content. The employed 23 polymorphic microsatellite loci exhibited three to twenty one alleles per locus with an average of 12 while total 270 alleles were detected. Two primer set PpSSR21 and PpSSR27 showed 100% polymorphism among the genotypes. The high oil yielding plant K19 showed different band pattern with the locus PpSSR04. From the Nei’s analysis it was found that maximum diversity exists between the full sib genotypes K10 and K2. Thus, the genotypes (K2 and K10) which are more diverse could be used further in improvement programme. Overall, the genotypes included in the study showed a correlation with their geographical origins such that genotypes from the same region tend to have higher genetic similarity as compared to those from different regions. However, in UPGMA based Nei’s analysis, some genotypes were found not to be grouped based on geographical origins possibly due to the exchange of germplasm over time between farmers across the regions. Both molecular and oil content (biochemical) markers appeared useful in analyzing the extent of genetic diversity in P. pinnata. The result of these analyses will help to better understand the genetic diversity and relationship among populations constituting a set of useful background information that can be used as a basis for future breeding strategy and improvement of the species.
A Step into Future Fuel Industrial Effluents into Bioethanol: A Review
Authors: Ganesh R. S. Vidhya , Devi R. Parimala , Ramesh D. , Karthikeyan S. , Murugananthi D.
Published: September 2023

Industrial revolution in agro based industries with improved technologies, machineries, etc. has resulted in the ease of operation, availability of increased number of value added products in the field of agriculture, effective labour management, etc. Agro industries are one of the major contributors for environmental pollution and accounts for about 10-15% for pollution. As the wastes generated from agro-industries are of biological origin, they can be effectively reused; if their alternate uses are explored. As these industrial effluents contain lignocellulose, cellulose, and hemicellulose, which are rich sources of lignin, and cellulose, it is possible to use these materials as a substrate to produce bioethanol. Our current review focuses on bioethanol production from different industrial effluents and Bio-microbial based fermentation.
Level of Awareness, Adoption and Constraints of Jasmine Growers
Authors: Anand G. , Jaisridhar P. , Janakirani A. , Karthikeyan C. , Sheeba S. Mercy
Published: September 2023

The Tiruchirappalli (Trichy) and Dindigul districts of Tamil Nadu state were purposively taken for studying objectives viz., profile, awareness, adoption and constraints faced by the jasmine growers. The sampling technique was multi-stage purposive sampling and the research design adopted was descriptive method. A total sample size of 160 (jasmine growers). The secondary data was collected through structured interview schedule. The frequency and percentage were worked-out to quantify the secondary data. PRA preference ranking/problem ranking matrix methodology was used to rank the production and marketing led constraints based on the perceived level of severity by the jasmine growers.  Likewise to study the determinants of awareness and adoption with that of the profile, the correction and regression co-efficient was used. It was evident that, there was cent percent awareness and adoption of variety, planting season. Though there was cent percent awareness on pruning technique, only 88.13 % adopted the practice. Very least awareness level (7.50 % & 14.38 %) was observed with respect to post harvest management practice like enhancing shelf-life and off-season flowering technology respectively. The proportion of non-adopter were high with respect to bio-fertilizer application (78.13 %), use of bio-stimulant (81.88 %), off-season flowering spraying (90.63 %) and enhancement of shelf-life through boric acid (100 %). Majority (71.88 %) of farmers were having only medium level of awareness, similarly little more than half (58.75 %) of the farmers had only medium level of adoption. The score obtained through problem matrix ranking revealed that, labour shortage during peak flowering season with highest mean score of 35.50 was ranked as foremost constraint in production and Price fluctuation /market risk with highest mean score of 37.50 was perceived as the foremost constraint in marketing of jasmine.
Effect of Weather Parameters on of Pests and Diseases in Groundnut and Castor in Salem District of Tamil Nadu, India
Authors: Kanna S. Suganya , Premalatha K. , Kavitha K. , Vijayakumar M. , Dheebakaran Ga. , Bhuvaneswari K.
Published: September 2023

The roving survey on the incidence of pests and diseases in groundnut and castor was conducted from August, 2020 to March 2021 in Salem district at fortnight intervals revealed that, in groundnut , leaffolder (20.38%), cutworms S. litura (1.63/20 pls), thrips (10.69/20 pls), leaf spot (15.25%) and root rot (6.31%) , similarly in castor pests, whiteflies (23.06/20 pls), A. janata (8.38/20 pls), S. litura (10.19/ 20 pls), thrips (11.63 / 20 pls), C. punctiferalis (7.25/20 pls), alternaria blight (17.56%) and botrytis rot (4.19%) were found feeding /infecting on different parts of the crops. The correlation with weather parameters indicated, positive correlation of rainfall, relative humidity and wind speed on incidence of leaffolder (0.47998, 0.311421 and 0.339961) but rainfall and relative humidity increased root rot (0.433059 and 0.393255) whereas, maximum temperature influenced high infection of leafspot (0.67911) in groundnut. The whiteflies incidence in castor was positively correlated with (0.490967) and rainfall (0.389125) whereas, lepidopteran pests by relative humidity (0.61212) and rainfall (0.49415). The thrips and botrytis rot were influenced by relative humidity and rainfall rot (0.65914 and 0.77965, 0.57456 and 0.82709). But natural enemies in groundnut and castor had non-significant correlation with weather parameters.
Effect of Organic and Inorganic Fertilizers on Soil Physical Properties & Nutrients Content and Uptake of Summer Green Gram
Authors: Kharadi R. R. , Bhuriya K. P. , Bamaniya V. P. , Pargi K. L.
Published: September 2023

The investigation was carried out during summer season to know the effect of different organic and inorganic fertilizers on physicochemical properties of soil & content and uptake of plants. The experiment was laid out in factorial randomized block design (FRBD) followed by twelve treatments with four replications. Water holding capacity, bulk density, porosity of soil was not significantly influenced by application of organic and inorganic fertilizers at harvest. Application of vermicompost @ 1.0 t ha-1 recorded significantly higher nitrogen content & uptake in seed and stover and potassium content in stover of green gram which was at par with incorporation of FYM @ 4 t ha-1 but phosphorus content & uptake was not significantly influenced by either incorporation of FYM or vermicompost or inorganic fertilizer. The use of 100% RDF (20 kg N + 40 kg P2O5 ha-1) resulted in significantly higher uptake of nitrogen and potassium by seed, stover and total uptake by crop and were at par with the application of 75% RDF (15 kg N + 30 kg P2O5 ha-1). Nitrogen, phosphorus and potassium content & uptake in seed, stover and total uptake of green gram was significantly higher recorded with the incorporation of FYM @ 4 t ha-1 which was at par with application of vermicompost @ 1 t ha-1. Application of farm yard manure @ 4 t ha-1 or vermicompost @ 1 t ha-1 along with inorganic fertilizers @ 75% RDF (15 kg N + 30 kg P2O5 ha-1) is best suited for improving physico-chemical properties of soil and nutrients content & uptake of green gram.
An Outlook on GWAS with a Special Focus on Solanaceous Vegetable Crops – A Review
Authors: Harish A.  , Ramesh Kumar A.  , Manivannan S.  , Senthil Kumar S.
Published: September 2023

The commercial solanaceous group of vegetables viz., Tomato, Brinjal, Peppers, and Potatoes hold a prime position among all other vegetables in terms of cultivation and consumption worldwide. These vegetables are consumed fresh by all strata of people and are also used as raw materials in the processing industries. Hence, most plant breeders have a keen interest in the crop improvement of these crops emphasizing yield improvement, quality and nutraceuticals enrichment and imparting resistance to various biotic and abiotic stresses in accordance with climate change. Most of the desirable traits are polygenic in nature which may have a complex inheritance pattern. It is essential to have clear-cut knowledge of the expression frequencies of multiple genes/alleles governing a particular quantitative trait/phenotype, the methods employed to examine and comprehend the candidate genes governing one or various characteristics in plants are quantitative trait loci mapping and genome-wide association studies. In This review, we have discussed GWAS and its future perspectives and made efforts to tabulate the recent past works done in solanaceous vegetable crops using this approach. GWAS is a attractive strategy that constitutes an important advancement in genetic analysis and has unquestionably proven to be a useful tool in identifying candidate genes, which is justified in this article.
Quantification of Antimicrobial Compounds Produced by Lactic Acid Bacteria Isolated from Pulses
Authors: Gouthami Bashipangu , Ramalakshmi A. , Balakrishnan M. , Karthikeyan S. , Paranidharan V.
Published: September 2023

In this study, 11 LAB isolates were isolated from the pulses (green gram and black gram) were tested for biochemical characteristics (catalase, MR-VP, citrate utilization, nitrate reduction) based on these tests four isolates were evaluated for their antimicrobial activity against three prominent pathogens: Escherichia coli, Pseudomonas aeruginosa, and Aspergillus flavus NRRL3357 under different pH 9 (5.5, 6.5, 7.5 and 8.5) and temperature (17ºC, 27ºC, and 40ºC). Among the four isolates, one isolate LB4 exhibited notable antimicrobial efficacy against all three pathogens under pH (6.5) 8.1± 0.6 mm, 8.3 ± 0.5 mm, and 6.6 ± 0.8 mm respectively. Optimum antimicrobial activity showed at temperature 27º against same pathogens the zone of inhibition mean values 10± 0.9 mm, 5.0± 0.6 mm, 8.3± 1.2 mm respectively. LB4 isolate was tested for quantification of key metabolites after three days of incubation, lactic acid, acetic acid, and hydrogen peroxide. Lactic acid (4.6 g/l) and acetic acid (4.8 g/l) were consistently produced in higher amounts, while hydrogen peroxide production remained relatively low (0.58 g/l) by the LB4 isolate. The results indicated the intricate relationship between antimicrobial activity, environmental factors, and metabolite production, emphasizing the promising role of this isolate in combating microbial infections under diverse conditions.
Influence of Organic Manure and Inorganic Fertilizers on Growth and Yield of Radish (Raphanus sativus L.) in Gird Region of Madhya Pradesh, India
Authors: Kumar Sumit , Kumar Pushpendra , Jatav Vinod , Dukpa Pinkey , Suman Shekhar
Published: September 2023

A field experiment was conducted to study the effect of organic manure and inorganic fertilizers on growth and yield of Radish (Raphanus sativus L.) in Grid region of Madhya Pradesh as factorial based on the randomized block design(RBD) with three replication and  Ten treatments viz., T1-(100% NPK through inorganic sources), T2-(100% NPK through Farm Yard manure (16t/ha)), T3-(100% NPK through Vermicompost (12t/ha)), T4-(100% NPK through Poultry Manure (9.48t/ha)), T5-(75% NPK+25%N through FYM), T6-(75% NPK+25% N through Vermicompost), T7-(75% NPK+25% N through Poultry manure), T8-(50% NPK+50% N through FYM), T9-(50% NPK+50% N through Vermicompost), T10-(50% NPK+50% N through Poultry manure) were made up of singlevariety Ivory white the experiment was planted in the CRC-II, School of agriculture, ITM University Gwalior. At all of the periodic crop growth phases except at 15 DAS, T6 showed significant plant height and leaf count increases across crop phases. T5, T6 had maximum heights; T3, T10 had minimum. T5, T6, T8 displayed the highest leaf counts; T1 the least. Leaf lengths followed a similar trend, with T8, T6 having the longest; T1 the shortest. Overall, T6 exhibited prominent growth in both height and leaf attributes, while T1 consistently showed the lowest values throughout all stages and measurements. The conventional practices T6 had significant positive influence on yield and yield attributing parameters, viz; root length (35.05cm), weight of whole plant (418.91g), initial fresh weight of roots (355.54g) but initial fresh weight of leaves (72.52g) in recorded in treatment T2, root diameter (50.61mm), girth of root (12.3cm), dry weight of leaves (13.49g) measured in T2, dry weight of root (102.19g), root yield per plot (21.33kg), root yield per hectare (319.98qha-1). Conclusion-: Economically the application of 75% NPK+25% N through vermicompost gave maximum net return (Rs. 262553.80) and BC ratio (3.94).
Determination of Virulence Genes in Extended Spectrum Beta Lactamase-Producing Escherichia coli Isolated from Fresh Leafy Vegetables Sold in Rivers State, Nigeria
Authors: Achinike Okwelle, Austin , Osakuade, Felicia O.
Published: September 2023

Extended-spectrum β-lactamases (ESBL’S) are a rapidly growing group of β-lactamases which have the ability to hydrolyze third generation antibiotics such as Cephalosporins and Aztreonam. The aim of this study is the determination of virulence genes in ESBL- producing Escherichia. coli isolated from cabbage, spinach and water leaf. but are inhibited by Clavulanic Acid. The randomised experimental design was used to collect cabbage (Brassica oleracea), water leaf (Hydrophyllum macrophyllum) and spinach (Spinacia oleracea) samples from retailer sellers in two different markets (Choba and Rumuosi daily markets) of Obio/Akpor Local Government Area, Rivers State. Water leaf samples had a mean count of 2.9×103, spinach sample mean count was 2.8×104 Cfu/g and the highest, while the lowest mean count was obtained from cabbage samples; 1.6×103 Cfu/g.    The study has established the presence of pathogenic E. coli (Enterohaemorrhagic) which are Shiga toxin producers that are Highly virulent with low infections doses.
Applicability of the 1470 Nm Diode Laser in Facial Aesthetics: An Evidence-Based Review
Authors: Furtado Gisele Rosada Donola , Barbosa Kledson Lopes , Costa Michelle Fechine , Lustosa Diogo Belas , Castilho Vivian Almeida , Tardin Claudia Dazzi dos Reis , Paulino Ana Carolina Pereira , Valenca Joao Luiz Batista , Gomes Flavianny Silva Artiaga Andrade
Published: September 2023

Introduction: Endolaser or Endolift® is a minimally invasive procedure carried out using a diode laser with a wavelength that can range from 980 to 1470 nm. This laser is inserted into the subcutaneous layer through an optical fibre probe to reduce fat and induce skin retraction via neocollagenesis.

Objectives: To assess the effects of the 1470 nm diode laser on subdermal lipolysis and rejuvenation based on evidence-based practice.

Methodology: An evidence-based literature review was conducted to elucidate the impact of the 1470 nm diode laser on facial rejuvenation. This review involved an exploration of scientific articles published and accessible within the databases MEDLINE, PubMed, SCIELO, and LILACS, spanning the years from 2013 to 2023.

Results: Six reports utilising the 1470 nm diode laser for aesthetic purposes were identified, underscoring the prevailing knowledge gap regarding applying the 1470 nm diode laser for aesthetic purposes such as lipolysis and as an adjunct for facial rejuvenation.

Conclusion: While the 1470 nm diode laser is currently widespread within the domain of facial aesthetics, a constrained body of research with a high level of scientific evidence exists. This suggests an urgent requirement for well-designed further investigations, such as randomised clinical trials.
Editorial: corpo e cognição
Authors: Santana Ivani , Adeodato Beatriz
Published: September 2023

Os estudos contemporâneos sobre o corpo, advindos das ciências cognitivas, têm possibilitado novos olhares sobre a corporalidade na dança, na performance, no teatro e nas artes cênicas em geral. Principalmente a partir do filósofo francês Maurice Merleau-Ponty, com seu livro Phénoménologie de la Perception (1945), atravessamos marcos importantes,como a Teoria Enativista, proposta por Francisco Varela, Evan Thompson e Eleonor Rosch, no livro The Embodied Mind, Cognitive Science and Human Experience (1991), o relevante trabalho do linguista George Lakoff e do filósofoMark Johnson, com o Philosophy in the Flash: the embodied mind and its challenge to Western thought (1999), ou ainda, Being There: putting brain, body, and world together again, de autoria de Andy Clark (1997), apenas para citar algunsnomes recorrentes em teses, dissertações e artigos no campo das artes cênicas.
Knockout of the BRAP homolog in mice leads to abnormal tracheal cilia
Authors: Wang Hui , Zuo Suhui , Zheng Jiaoyun , Peng Zhi , Yao Xueping , Wang Jie , Weber Horst Christian , Qin Xiaoqun , Xiang Yang , Liu Chi , Ji Ming , Liu Huijun , Pan Lang , Qu Xiangping
Published: September 2023

Both bombesin receptor‐activated protein (BRAP) and its mouse homolog have been found to be expressed in bronchial epithelia but with unclear functions. Using electron microscopy combined with histological assays, we found that BRAP homolog deficiency in mice led to abnormal tracheal cilia. Rab‐3A‐interacting protein (Rabin8), a protein that might play a role in cilia development, was screened by yeast two‐hybrid and further verified to have interaction with human BRAP by co‐immunoprecipitation and pulldown assays. The expression levels of Rabin8, together with acetylated α‐tubulin, a marker of cilia, were either downregulated by knockdown of BRAP or upregulated by overexpression of BRAP in cultured immortalized human bronchial epithelial cells. These results reveal a role for BRAP in airway cilia formation.
Are there metacognitive benefits of learner‐ and instructor‐generated visualizations?
Authors: Fiorella Logan , Jaeger Allison J.
Published: September 2023

This study explored how different formats of instructional visuals affect the accuracy of students' metacognitive judgments. Undergraduates (n = 133) studied a series of five biology texts and made judgments of learning. Students were assigned randomly to study the texts only (text only), study the texts with provided visuals (provided visuals group), study the texts and generate their own visuals (learner‐generated visuals group), or study the texts and observe animations of instructor‐generated visuals (instructor‐generated visuals group). After studying the texts and making judgments of learning, all students completed multiple‐choice comprehension tests on each text. The learner‐generated and instructor‐generated visuals groups exhibited significantly higher relative judgment accuracy than the text only and provided visuals groups, though this effect was relatively small. The learner‐generated visuals group also required more study time and was more likely to report the use of visual cues when making their judgments of learning.
Fracture‐Resistant and Thermally Insulating Ultrahigh‐Temperature Carbide Foams
Authors: Nisar Ambreen , Lopez Kazue Orikasa , Thomas Tony , Boesl Benjamin , Agarwal Arvind
Published: September 2023

Dense ultrahigh‐temperature ceramics (UHTCs) carbides are recognized as potential materials for thermal protection systems (TPS) owing to properties beyond existing structural materials’ capabilities. Recent advances in UHTCs have enabled the development of multiscale porous microstructures. Herein, it is highlighted that the porosity in UHTCs are no longer treated as a defect but as a functional property specifically tailored for thermal insulation. It is a promising solution to design and fabricate bulk UHTC foams via a freeze‐drying (FD) approach followed by calibrated pressureless spark plasma sintering. Herein, monolithic TaC and HfC UHTC foams and their composite show the partial solid–solution formation of (Ta, Hf)C with porosity ≥50%. TaC–HfC foam (≈80–92 N) shows an intermediate load‐bearing capability compared to monolithic TaC (≈120–135 N) and HfC (≈28–35 N) foams, with no evident cracking on the sample surface. The thermal conductivity of partial solid‐solution TaC–HfC foam increases up to fivefold compared to parent UHTC foams. In the results, solid solutions’ efficacy and pores’ unidirectionality in providing thermal insulation to TaC–HfC while maintaining its high‐load bearing capability are illustrated. The developed technique establishes a new paradigm shift in UHTCs, expanding their potential for TPS in extreme environments.
Selection of Ti Alloys for Bio‐Implants: An Application of the Ashby Approach with Conflicting Objectives
Authors: Salvador Camilo A. F. , Van Landeghem Hugo P. , Antunes Renato A.
Published: September 2023

The aim of the present work is to develop a materials selection strategy for biomedical Ti alloys by combining Ashby's method with a recently published dataset. The selection process concerns mechanical properties such as yield strength, elastic modulus, deformation at rupture, and the cost of the material. Outputs of the selection process point to alloys from both Ti‐Nb and Ti‐Mo systems as viable candidates for joint replacement materials. Additionally, this work discusses the crucial role of certain alloying elements in obtaining high elastic admissible strains, that is, a high yield strength‐to‐modulus ratio. Adding solutes such as Ta, Zr, Sn, Fe, and O is vital to stabilizing the β phase, suppressing the ω phase and increasing mechanical strength. Considering the minimum requirements of a 400 MPa yield strength, and 10% elongation at rupture, the best alloys identified via a multi‐objective optimization approach are Ti‐4.6Mo‐3.3Sn‐1.0Fe‐0.4O, Ti‐22.1Nb‐5Zr‐1.0Fe, and Ti‐20.3Nb‐4.7Ta‐2.5Sn (at%). These compositions present elastic moduli lower than 55 GPa, with an optimal trade‐off between a high elastic admissible strain and low cost. Updated property maps and analyses of conflicting properties are provided to support the conclusions.
Deposition of PEDOT:PSS via Atmospheric Pressure Plasma Torch
Authors: Arkhangelskiy Artem , Quaranta Alberto , Pancheri Lucio , Maniglio Devid
Published: September 2023

Creating conductive biocompatible coatings with enhanced stability and adhesion can be achieved with cold plasma‐assisted processes that provide surface modification, and assisted polymerization at mild conditions and room temperature. Herein, a novel method is reported for the controlled deposition of conductive polymer poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) on substrates with different characteristics: polyethylene terephthalate, poly(dimethylsiloxane), and soda‐lime glass. The plasma deposited PEDOT:PSS films are studied by atomic force microscopy, scanning electron microscopy, and Fourier transform infrared spectroscopy, and tested for stability and adhesion. The electrical resistance is obtained by a four‐point probe station to investigate the influence of plasma reaction and etching mechanism on the reproducibility of the electrical parameters. The proposed method is also successfully developed for the deposition of stacked layers structures, with the aim to design basic passive electrical components, such as a resistor or a capacitor. The possibility of realizing complex shapes by selective area deposition can enable the realization of advanced biosensor devices.
Multifunctional Mesoporous Polydopamine‐Based Systematic Delivery of STING Agonist for Enhanced Synergistic Photothermal‐Immunotherapy
Authors: Zeng Wenfeng , Li Zimu , Huang Qili , Ding Chendi , Yang Li , Wang Wenyan , Shi Zhaoqing , Yang Yao , Chen Hongzhong , Mei Lin , Zeng Xiaowei
Published: September 2023

The therapeutic application of STING agonists in various malignancies has been limited by factors such as the inability of systemic administration and the immunosuppressive tumor microenvironment. Herein, this work reports a mesoporous polydopamine‐based multifunctional nanoplatform loaded with STING agonist MSA‐2 and chelated with Mn2+ for synergistic photothermal and STING activation‐based immunotherapy. The nanoplatform effectively delivers MSA‐2 to the tumor site and intelligently releases its contents through acid degradation, facilitated by the photothermal effect. Additionally, the thermal ablation of tumor tissue can induce immunogenic cell death, which helps alleviate the immunosuppressive tumor microenvironment, thereby enhancing the efficacy of MSA‐2. Furthermore, Mn2+ works as a dual‐acting STING sensitizer and MRI contrast agent which not only boosts the immune response but also allows real‐time MRI tracking of the nanoplatform. This strategy is proved highly efficacious both in impeding primary/metastatic tumor and in eliciting a robust tumor‐specific immune response. Collectively, an effective multifunctional nanoplatform for the systemic delivery of STING agonist which synergized photothermal therapy and STING pathway activation‐mediated immunotherapy is highlighted here to provide new ideas and strategies for optimizing combination therapy for cancer treatment.
Engineering Near‐Infrared Plasmonic Spiky Gold Nanostructures for Highly Efficient Surface‐Enhanced Raman Spectroscopy‐Guided Cancer Hyperthermia Therapy
Authors: Jiang Renting , Li Jianqin , Li Linhu , Lu Yaxuan , Zhang Huiming , Li Ming
Published: September 2023

Cancer phototheranostics utilizing plasmonic materials is attracting considerable interest due to its high spatiotemporal precision and specificity, remote controllability, superior therapeutic efficacy, and low systemic side effects. Exploring new plasmonic materials with excellent plasmonic and photothermal properties is at the frontier of cancer phototheranostics. Herein, this work systematically investigates the plasmonic and photothermal properties of spiky Au nanoparticles (NPs) with different shaped central cores – spiky Au nanosphere , spiky Au nanocube and spiky Au nanorod (AuNR). It is shown that the shape of the central core in spiky Au NPs has significant effects on their surface‐enhanced Raman spectroscopy (SERS) and photothermal performances, and spiky Au NPs of a spherical or cubic core are much superior for near‐infrared (NIR) SERS detection and hyperthermia therapy in comparison with spiky AuNRs. The spiky Au NP‐based SERS probes demonstrate the remarkable capability for SERS imaging of live cells and dynamic visualization of tumors in a 4T1 breast tumor mouse model after intravenous administration. Moreover, in vivo studies show exceptional hyperthermia therapeutic effects of such SERS probes against 4T1 breast tumors under NIR irradiation. This study suggests the potential utility of spiky Au NP‐based SERS probes for efficient SERS‐guided cancer hyperthermia therapy.
A Tumoricidal Lipoprotein Complex Electrostatically Stabilized on Mesoporous Silica as Nanotherapeutics and Nanoadjuvant for Potentiating Immunotherapy of Triple Negative Breast Cancer
Authors: Pei Wei , Li Yuqing , Wu Yixian , Wu Yuan , Cai Ling , Wang Shaozhuo , Wang Shoulin , Chen Jin
Published: September 2023

As the most aggressive subtype, triple‐negative breast cancer (TNBC) without definitive targets represents a high probability of metastasis. Nevertheless, the presence of high‐level tumor‐infiltrating lymphocytes in the TNBC tumor microenvironment (TME) suggests patients may benefit from immunotherapy. In this study, bovine α‐lactalbumin coupled with oleic acid that forms tumoricidal lipid–protein complex (BAMLET) is electrostatically stabilized on the surface of amino‐functionalized mesoporous silica nanoparticles (MSN‐NH2). It is found that MSN‐NH2 may cause partial conformational changes of immobilized proteins due to electrostatic interactions. Therefore, BAMLET covered MSN‐NH2 (BMSN) as a drug cargo that can not only induce selectively oncolytic effect but kill tumor cells with rapid kinetics. Moreover, the hemolytic activity of BMSN conjugated with pre‐formed serum protein corona is largely reduced which may avoid the poor hemocompatibility caused by BAMLET. Furthermore, the in vivo study indicates that the combinational use of drug‐loaded BMSN and immune checkpoint small‐molecule inhibitor can efficiently inhibit the growth of solid TNBC tumors and activate immune response by sufficient infiltration of immune cells in the TME and prevent the seeding of circulating tumor cells. Therefore, the constructed BMSN provides an integrated nanotherapeutics and a nanoadjuvant with superior anticancer performance to combat TNBC.
Bend‐Resistant and Energy‐Friendly GO‐PVA/PVA Polymer Electret Synaptic Transistors for Neuromorphic Computations
Authors: Fu Xiao , Liang Zhihao , Shuai Wentao , Li Yushan , Ning Honglong , Su Guoping , Lu Xubing , Xie Weiguang , Yao Rihui , Peng Junbiao
Published: September 2023

Polymer electret synaptic transistor is a promising three‐terminal artificial synaptic device. In this work, the electrical characteristics of the composite insulator and transistor are enhanced by modulating the concentration of the 2D nanofiller graphene oxide (GO) and the stacked film structure based on a polyvinyl alcohol (PVA) matrix. The GO‐PVA/PVA polymer electret synaptic transistors before and after dynamic/static bending exhibit typical synaptic characteristics, including short‐term plasticity, long‐term plasticity, pair‐pulse facilitation, spike‐timing‐dependent plasticity, and “learning–forgetting–relearning” features. Importantly, the device exhibits good cycling stability, uniformity and linearity in the potentiation‐depression cycling test, which is beneficial for improving the accuracy of neuromorphic computations. Also, it shows extremely low energy consumption (≈0.32 fJ). The recognition accuracy of images is simulated based on the constructed artificial neural network, which achieves 86.8% for the MNIST dataset. In addition, the devices maintain high recognition accuracy after dynamic/static bending, indicating that the devices are extremely bend‐resistant. The GO‐PVA/PVA polymer electret synaptic transistor is expected to be a potential candidate for neuromorphic computations and electronic skin.
DNA Origami: From Molecular Folding Art to Drug Delivery Technology
Authors: Jiang Qiao , Shang Yingxu , Xie Yiming , Ding Baoquan
Published: September 2023

DNA molecules that store genetic information in living creatures can be repurposed as building blocks to construct artificial architectures, ranging from the nanoscale to the microscale. The precise fabrication of self‐assembled DNA nanomaterials and their various applications have greatly impacted nanoscience and nanotechnology. More specifically, the DNA origami technique has realized the assembly of various nanostructures featuring rationally predesigned geometries, precise addressability, and versatile programmability, as well as remarkable biocompatibility. These features have elevated DNA origami from academic interest to an emerging class of drug delivery platform for a wide range of diseases. In this minireview, the latest advances in the burgeoning field of DNA‐origami‐based innovative platforms for regulating biological functions and delivering versatile drugs are presented. Challenges regarding the novel drug vehicle's safety, stability, targeting strategy, and future clinical translation are also discussed.