bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of leukoaraiosis severity on the association of outcomes of mechanical thrombectomy for acute ischemic stroke: a systematic review and a meta-analysis
Authors: Huo Longwen , Chen Penghui , Wang Zhongxiu , Li Xiandong , Zhou Jie , Wang Chao , Xing Dajiang , Wang Shouchun
Published: August 2020

Background

Leukoaraiosis (LA) severity is associated with poor outcome after mechanical thrombectomy (MT) for acute ischemic stroke (AIS) caused by large vessel occlusion. This meta-analysis aimed to assess the association of LA severity with AIS-related risk factors and outcomes of MT.

Methods

PubMed, Web of Science, EMBASE, and Cochrane Collaboration Database was searched for studies on MT for AIS with LA. We conducted a random-effects meta-analysis for the prevalence of stroke risk factors and the MT outcome in the absent to moderate LA and severe LA groups.

Results

We included seven cohort studies involving 1294 participants (1019 with absent to moderate LA and 275 with severe LA). The absent to moderate LA group had a significantly lower prevalence of coronary artery disease (odds ratio [OR] 0.43; 95% CI 0.29–0.66), atrial fibrillation (OR, 0.26; 95% CI 0.17–0.38), hypertension (OR, 0.39; 95% CI 0.24–0.61), and ischemic stroke (OR, 0.27; 95% CI 0.15–0.50) than the severe LA group. There were no significant between-group differences in symptom onset to recanalization time (364.4 versus 356.2 min, mean difference 19.4; 95% CI − 28.3 to 67.2), final recanalization rate (modified thrombolysis in cerebral infarction score of 2b/3; OR, 0.87; 95% CI 0.55–1.38), and symptomatic intracranial hemorrhage (OR, 0.62; 95% CI 0.34–1.11). The absent to moderate LA group had a higher good functional outcome (modified Rankin Scale score of 0–2 at 90 days; OR, 4.55; 95% CI 3.20–6.47) and a lower mortality rate (179/1019 vs 108/275; OR, 0.28; 95% CI 0.20–0.39).

Conclusion

There are unique differences in the characteristics of risk factors and clinical outcomes of ischemic stroke across patients with LA of different severity. Patients with severe LA are more likely to be associated with risk factors for cerebrovascular disease and have a poor post-MT outcome.
Impact of catheterization on shear-mediated arterial dilation in healthy young men
Authors: Tryfonos Andrea , Cocks Matthew , Rasoul Debar , Mills Joseph , Green Daniel J. , Dawson Ellen A.
Published: August 2020

Purpose

Animal studies have shown that endothelial denudation abolishes vasodilation in response to increased shear stress. Interestingly, shear-mediated dilation has been reported to be reduced, but not abolished, in coronary artery disease (CAD) patients following catheterization. However, it is not known whether this resulted from a priori endothelial dysfunction in this diseased population. In this study, we evaluated shear-mediated dilation following catheterization in healthy young men.

Methods

Twenty-six (age: 24.4 ± 3.8 years, BMI: 24.3 ± 2.8 kg m−2, VO2peak: 50.5 ± 8.8 ml/kg/min) healthy males underwent unilateral transradial catheterization. Shear-mediated dilation of both radial arteries was measured using flow-mediated dilation (FMD) pre-, and 7 days post-catheterization.

Results

FMD was reduced in the catheterized arm [9.3 ± 4.1% to 4.3 ± 4.1% (P < 0.001)] post-catheterization, whereas no change was observed in the control arm [8.4 ± 3.8% to 7.3 ± 3.8% (P = 0.168)]. FMD was completely abolished in the catheterized arm in five participants. Baseline diameter (P = 0.001) and peak diameter during FMD (P = 0.035) were increased in the catheterized arm 7 days post-catheterization (baseline: 2.3 ± 0.3 to 2.6 ± 0.2 mm, P < 0.001, peak: 2.5 ± 0.3 to 2.7 ± 0.3 mm, P = 0.001), with no change in the control arm (baseline: 2.3 ± 0.3 to 2.3 ± 0.3 mm, P = 0.288, peak: 2.5 ± 0.3 to 2.5 ± 0.3 mm, P = 0.608).

Conclusion

This is the first study in young healthy individuals with intact a priori endothelial function to provide evidence of impaired shear-mediated dilation following catheterization. When combined with earlier studies in CAD patients, our data suggest the catheterization impairs artery function in humans.
Antibiotic prophylaxis in acute cholecystectomy revisited: results of a double-blind randomised controlled trial
Authors: Jaafar Gona , Sandblom Gabriel , Lundell Lars , Hammarqvist Folke
Published: August 2020

Purpose

Evidence supporting the value of preoperative antibiotic prophylaxis (PAP) in surgery for acute cholecystitis is lacking. This study aimed to shed light on whether PAP in acute cholecystectomy for cholecystitis reduces the postoperative infectious complication (PIC) rate. Secondary outcomes were the prevalence of bacteriobilia, CRP values and leucocyte counts.

Methods

The study was performed as a single-centre, double-blinded, placebo-controlled, randomised study. Patients with acute cholecystitis amenable for acute laparoscopic cholecystectomy were randomly assigned to either PAP (piperacillin/ tazobactam) or placebo, and the subsequent clinical course was followed.

Results

A total of 106 patients were enrolled, 16 of whom were excluded due to protocol violation. PIC developed in 22 of the 90 patients included with no significant difference between the PAP and placebo groups (8 patients in the PAP group and 14 in the placebo arm, p = 0.193). The PIC rate was significantly higher in patients with a raised CRP at randomisation and on the day of surgery and in cases of conversion to an open procedure (p = 0.008, 0.004 and 0.017, respectively) but with no differences between the study groups.

Conclusion

PAP does not affect the risk for PIC in patients with acute cholecystitis. The major risk factors determining PIC in these patients need defining, in particular, the impact of bacteriobilia.

Trial registration

The study was registered at clinicaltrials.gov (NCT02619149) December 2, 2015.
Genetic diversity of phytoplasma strains infecting chrysanthemum varieties in India and their possible natural reservoirs
Authors: Taloh Aido , Raju D. V. S. , Banyal Namita , Kumar Gunjeet , Panda Priyam , Manimekalai R. , Marcone Carmine , Rao G. P.
Published: August 2020

Symptoms typical of phytoplasma infection such as phyllody, virescence, witches’ broom and yellowing were observed in 12 varieties of Chrysanthemum morifolium in floral nurseries and experimental fields at New Delhi, Karnataka, Maharashtra and Andhra Pradesh, India, during surveys made from 2015 to 2017. Disease incidence ranged from 15 to 30%. Phytoplasma presence was confirmed in all symptomatic chrysanthemum varieties by molecular identification assays. Sequence comparison, phylogenetic and in silico RFLP analyses of 16S rDNA sequences allowed the identification of the chrysanthemum infecting phytoplasma strains into different ribosomal groups and subgroups, namely 16SrI, 16SrII-D, 16SrVI-D and 16SrXIV. Detection of phytoplasma strains of 16SrII-D subgroup were also confirmed in symptomatic Chenopodium album and Parthenium hysterophorus plants grown in and around the surveyed chrysanthemum fields at New Delhi, whereas 16SrVI-D phytoplasma strains were detected in symptomatic Cannabis sativa weed and leafhopper Hishimonus phycitis individuals collected from the symptomatic chrysanthemum fields at New Delhi. This is the first report on the presence of 16SrVI and 16SrXIV groups of phytoplasmas in chrysanthemum plants. Studies on genetic diversity of phytoplasmas infecting the major chrysanthemum varieties in India and their epidemiological aspects had previously not been reported. The detection and identification of phytoplasmas in different chrysanthemum varieties could contribute to increase the awareness among farmers in the management of these diseases.
Athens and Delphi in the Classical Period: Exploring a Religious Relationship
Authors: Bowden Hugh
Published: August 2020

In this article, I present an interpretation in religious terms of what Athenians were doing when they went to Delphi as representatives of their city. I begin by briefly outlining the key moments of Athenian involvement with Delphi in the classical period, which is roughly from 479 to 338 BCE, and the general relationship between city and sanctuary. I then look at the activities of the Athenian delegates to the Delphic Amphiktyony, whose responsibilities included representing the city of Athens at the festival of thePylaiaat Anthela and offering sacrifice at Delphi. I then turn to sacred ambassadors coming to consult the oracle, and show that occasions of consultation were festival occasions and that the experience of thetheōroiwas profoundly religious. I demonstrate that more than any immediate political concerns, maintaining a good relationship with Apollo was central to these activities. Evidence will be drawn largely from inscriptions from Delphi and literary sources from Athens, dating to the period under investigation.
Contractibility of a persistence map preimage
Authors: Cyranka Jacek , Mischaikow Konstantin , Weibel Charles
Published: August 2020

This work is motivated by the following question in data-driven study of dynamical systems: given a dynamical system that is observed via time series of persistence diagrams that encode topological features of snapshots of solutions, what conclusions can be drawn about solutions of the original dynamical system? We address this challenge in the context of an N dimensional system of ordinary differential equation defined in $${\mathbb {R}}^N$$

R

N

. To each point in $${\mathbb {R}}^N$$

R

N

(e.g. an initial condition) we associate a persistence diagram. The main result of this paper is that under this association the preimage of every persistence diagram is contractible. As an application we provide conditions under which multiple time series of persistence diagrams can be used to conclude the existence of a fixed point of the differential equation that generates the time series.
A Techno-Functional Interpretation of the Lithic Assemblage from Fontana Ranuccio (Anagni, Central Italy): an Insight into a MIS 11 Human Behaviour
Authors: Grimaldi Stefano , Santaniello Fabio , Angelucci Diego E. , Bruni Luciano , Parenti Fabio
Published: August 2020

The techno-functional approach has been employed to better understand one of the more relevant artifact types generally found in Lower Palaeolithic sites: so-called small tools. Particularly, some Italian sites, such as Ficoncella, Isernia and others, have been the subject of specialized studies which provide evidence of an unexpected complexity of technical behaviours mainly related to highly specialized functional properties of the small tools. In this paper, we aim to enhance the debate on the topic by presenting a techno-functional study of the entire lithic assemblage coming from one of the most renown Middle Pleistocene sites in southern Europe, the open-air site of Fontana Ranuccio (Central Italy). Five groups of retouched tools have been identified: cutting tools, where retouch is usually applied to isolate a cutting edge on the blank; pointed tools, where retouch isolates a pointed edge; scrapers; and few other types of retouched tools such as notches and denticulates. We discuss a reconstruction of the reduction sequence in association with the functional features of the produced stone tools in order to better understand these Middle Pleistocene hominin behaviours. Broadly speaking, retouch seems to be used as a real technical process, not distinguishable from the reduction sequence. What seems relevant here is the need to modify the original morphology of flakes and cores in order to shape them into the final objectives of the production. In this perspective, blank production (débitage) and tool shaping (façonnage) are tightly interconnected one on the other.
Cervicothoracic Mechanical Impairment as Part of Complete Neurological Fall Risk Appraisal
Authors: Johnston Janine L. , Featherstone Graham , Harms Shane L. , Thomson Glen T. D.
Published: August 2020

Background:

Assessment of individuals at risk for falling entails comprehensive neurological and vestibular examinations. Chronic limitation in cervical mobility reduces gaze accuracy, potentially impairing navigation through complex visual environments. Additionally, humans with scoliosis have altered otolithic vestibular responses, causing imbalance. We sought to determine whether dynamic cervical mobility restrictions or static cervicothoracic impairments are also fall risk factors.

Methods:

We examined 435 patients referred for soft-tissue musculoskeletal complaints; 376 met criteria for inclusion (mean age 52; 266 women). Patients were divided into nonfallers, single fallers, and multiple fallers, less or greater than 65 years old. Subject characteristics, dynamic cervical rotations, and static cervicothoracic axial measurements were compared between groups. Fear of falling was evaluated using the Falls Efficacy Scale-International questionnaire.

Results:

Long-standing cervicothoracic pain and stiffness conferred increased risk of falling. Neck rotation amplitudes decreased with longer duration musculoskeletal symptoms and were significantly more restricted in fallers, doubling the risk of falling and contributing to increased fear of falling. Mid-thoracic scoliosis amplitudes increased over time, but static axial abnormalities were not greater among fallers, although thoracic kyphoscoliosis heightened fear of falling.

Conclusion:

In patients at fall risk, thoracic kyphoscoliosis and dynamic neck movements should be assessed, in addition to standard vestibular and neurological evaluations. Additionally, patients with soft tissue cervicothoracic pain and restricted mobility have increased fall frequency and fear of falling, independent of other fall risk factors and should undergo complete fall risk appraisal.
Effectiveness of a peer-led adolescent mental health intervention on HIV virological suppression and mental health in Zimbabwe: protocol of a cluster-randomised trial
Authors: Chinoda Silindweyinkosi , Mutsinze Abigail , Simms Victoria , Beji-Chauke Rhulani , Verhey Ruth , Robinson Joanna , Barker Taryn , Mugurungi Owen , Apollo Tsitsi , Munetsi Epiphany , Sithole Dorcas , Weiss Helen A. , Chibanda Dixon , Willis Nicola
Published: August 2020

Background

Adolescents living with HIV (ALHIV) experience a high burden of mental health disorder which is a barrier to antiretroviral therapy adherence. In Zimbabwe, trained, mentored peer supporters living with HIV (Community Adolescent Treatment Supporters – CATS) have been found to improve adherence, viral suppression and psychosocial well-being among ALHIV. The Friendship Bench is the largest integrated mental health programme in Africa. We hypothesise that combining the CATS programme and Friendship Bench will improve mental health and virological suppression among ALHIV compared with the CATS programme alone.

Methods

We will conduct a cluster-randomised controlled trial in 60 clinics randomised 1:1 in five provinces. ALHIV attending the control arm clinics will receive standard CATS support and clinic support following the Ministry of Health guidelines. Those attending the intervention arm clinics will receive Friendship Bench problem-solving therapy, delivered by trained CATS. Participants with the signs of psychological distress will be referred to the clinic for further assessment and management. The primary outcome is HIV virological failure (≥1000 copies/ml) or death at 48 weeks. Secondary outcomes include the proportion of adolescents with common mental disorder symptoms (defined as Shona Symptom Questionnaire (SSQ-14) score ≥8), proportion with depression symptoms (defined as Patient Health Questionnaire (PHQ-9) score ≥11), symptom severity (mean SSQ-14 and PHQ-9 scores) and EQ-5D score for health-related quality of life.

Conclusions

This trial evaluates the effectiveness of peer-delivery of mental health care on mental health and HIV viral load among ALHIV. If effective this intervention has the potential to be scaled-up to improve these outcomes.

Trial registration: PACTR201810756862405. 08 October 2018.
On the von Neumann algebras associated to Yang–Baxter operators
Authors: Bikram Panchugopal , Kumar Rahul , Mohanta Rajeeb , Mukherjee Kunal , Saha Diptesh
Published: August 2020

Bożejko and Speicher associated a finite von Neumann algebra MT to a self-adjoint operator T on a complex Hilbert space of the form $\mathcal {H}\otimes \mathcal {H}$ which satisfies the Yang–Baxter relation and $ \left\| T \right\| < 1$. We show that if dim$(\mathcal {H})$ ⩾ 2, then MT is a factor when T admits an eigenvector of some special form.
Triangulating on Thought and Norms
Authors: LUDWIG KIRK
Published: August 2020

This article raises two questions about Robert Myers and Claudine Verheggen's terrific book,Donald Davidson's Triangulation Argument: A Philosophical Inquiry. The first question, concerning the first part of the book, is whether, starting from the assumption that a solitary individual cannot have thought contents, we can show that adding another individual to the picture cannot resolve the problem. The second question, concerning the second part, is whether a more sophisticated, decision-theoretic, Humean about the pro-attitudes can respond to the objections to the simple Humean view, and whether Davidson was not in fact just such a sophisticated decision-theoretic Humean.
Jeux dialogiques et processus discursif. Conséquences du débat entre Habermas et Brandom
Authors: SEBBAN YAËL
Published: August 2020

Dans cet article, nous soutenons que Habermas réduit, dans l'essai critique sur Brandom inclus dansVérité et justification(2001), la communication à sa forme étroitement dialogique et, ce faisant, tend à ignorer que le processus discursif est avant tout, pour Brandom, le produit d'une coordination partagée de différentes perspectives individuelles contribuant à faire avancer ce jeu de production et de demande de raisons. Nous proposons, d'une part, de procéder à une analyse critique de la position de Habermas, et d'autre part, de rendre justice à Brandom en soulignant la spécificité du processus communicatif discursif.
A breed apart and a breed below: creative music performance and the expert drummer
Authors: Bruford Bill
Published: August 2020

This article argues that contemporary systems theory explanations are insufficient when accounting for ‘in the moment’ creative musical performance. The system model's focus on a domain-changing contribution from an individual fails to offer a satisfactory account of the construction and assessment of the more everyday distributed and collaborative creativity undertaken by many popular music instrumentalists. A cultural psychology perspective, in contrast, situates distributed creativity inbetween people and objects rather than within them. Glăveanu's ‘Five As framework’ has particular utility in capturing the ordinary creativity that does not seek to change the domain but nevertheless contributes to it. The model is applied here to four case studies of expert instrumentalists that draw upon a combination of primary evidence, lived experience and original research.
‘Every time I dress myself, it go motherfuckin’ viral’: Post-verbal flows and memetic hype in Young Thug's mumble rap
Authors: Waugh Michael
Published: August 2020

Hip-hop studies have historically centred on issues of the ‘street’ or virtuosic lyricism and flow, foregrounded as evidence of the ‘seriousness’ of the genre. While these have undoubtedly been valuable theoretical approaches, the prominence of social networking in the 2010s (with its vast implications for communication and identity politics) has sculpted a generation of rappers whose vocal style and self-representation disintegrate prior assumptions about hip-hop identity. These artists, who have flourished in tandem with the rise of streaming services, have been disparagingly dubbed ‘mumble rap’ by traditionalists owing to the apparent indecipherability of their vocals and a lack of emphasis on observational or poetic lyricism. In this article I argue that this myopic label undervalues the groundbreakingly post-verbal nature of the music being created by these rappers, and highlights the innovations of mumble rap, exploring the centrality of social media, memes and streaming to its existence while critically examining its protagonists’ unconventionally stylised vocals. After analysing the impact of streaming, information overload and audience participation (through social media hype and memes) on contemporary hip-hop, I survey the growth of melodic Auto-Tuned vocals and repetitive lyricism in the work of pioneering mumble rappers such as Future, before turning to an extended examination of Atlanta's Young Thug, whose controversially malleable vocal style, which prioritises experimentation with vocal textures while confounding the rules of hip-hop flow, is mirrored by his impulsive exploitation of social media and androgynous fashion sense, establishing him as the most revolutionary archetype of so-called mumble rap.
State-led Financialization in China: The Case of the Government-guided Investment Fund
Authors: Pan Fenghua , Zhang Fangzhu , Wu Fulong
Published: August 2020

China is witnessing a growing trend towards financialization by the state. Drawing on the concept of state-led financialization, this study is the first to explore how the government-guided investment fund (GGIF) has evolved and spread throughout the country. The promotion policies and practices of the central government have laid the key foundation for the development of GGIFs, while local governments have quickly adopted this new financial tool, resulting in its widespread take up. State-owned enterprises are heavily involved in the operation of GGIFs, indicating that this market-oriented tool has largely failed to attract capital from the private sector. This study shows that state-led financialization in China has strengthened rather than weakened the influence of the state in the economy, which is not the case in most Western economies. However, the limitations and risks of the GGIF are also related to the dominant role of the state in GGIF operations.
Stochastic approach to study control strategies of Covid-19 pandemic in India
Authors: Chanu Athokpam Langlen , Singh R. K. Brojen
Published: August 2020

India is one of the severely affected countries by the Covid-19 pandemic at present. Within the stochastic framework of the SEQIR model, we studied publicly available data of the Covid-19 patients in India and analysed possible impacts of quarantine and social distancing as controlling strategies for the pandemic. Our stochastic simulation results clearly show that proper quarantine and social distancing should be maintained right from the start of the pandemic and continued until its end for effective control. This calls for a more disciplined social lifestyle in the future. However, only social distancing and quarantine of the exposed population are found not sufficient enough to end the pandemic in India. Therefore, implementation of other stringent policies like complete lockdown as well as increased testing of susceptible populations is necessary. The demographic stochasticity, which is quite visible in the system dynamics, has a critical role in regulating and controlling the pandemic.
Processing in the food chain: do cereals have to be processed to add value to the human diet?
Authors: Thielecke Frank , Lecerf Jean-Michel , Nugent Anne P.
Published: August 2020

Cereals and cereal products have a long history of use by humans. Recently, there have been some discussions regarding level of processing as a descriptor to define food products, including cereal-based foods. This has led to a somewhat emotional debate on food processing. Given the widespread inclusion of cereals in the diet, this review highlights the history of cereal processing as well as their consumption by humans. It provides an evidence-based discussion on their production, contribution to human nutrition, benefits and disadvantages. The present review illustrates the impact of processing on nutrients, as well as non-nutrients specifically in bread and ready-to-eat breakfast cereals (RTEC), two cereal-based foods which are widely consumed and integral parts of food-based dietary guidelines globally. As a category, most cereals must be processed in some way to enable consumption by humans as we are not equipped to survive exclusively on raw grains. Even thousands of years ago, the processing of cereals was a common practice by humans, turning raw grains into palatable, safe and nutritious foods. Modern processes for cereal-based products are efficient in providing safe and good-quality products to satisfy population needs, as well as helping to meet consumer expectations by providing a range of foods that allows for a varied and balanced diet. Today, RTEC and bread make significant contributions to dietary energy and nutrient requirements and underpin food-based dietary guidance globally. They have been positively linked with intake of dietary fibre, vitamins and minerals, especially when consumed as whole grain.
Distribution, abundance, and on-land threats to Cabo Verde seabirds
Authors: SEMEDO GILSON , PAIVA VITOR H. , MILITÃO TERESA , RODRIGUES ISABEL , DINIS HERCULANO A. , PEREIRA JORGE , MATOS DIANA , CEIA FILIPE R. , ALMEIDA NATHALIE M. , GERALDES PEDRO , SALDANHA SARAH , BARBOSA NADITO , HERNÁNDEZ-MONTERO MARCOS , FERNANDES CAROLINO , GONZÁLEZ-SÓLIS JACOB , RAMOS JAIME A.
Published: August 2020

Pelagic seabird populations have declined strongly worldwide. In the North Atlantic there was a huge reduction in seabird populations following the European colonization of the Azores, Madeira and Canary archipelagos but information on seabird status and distribution for the subtropical region of Cabo Verde is scarce, unavailable or dispersed in grey literature. We compiled and compared the historical and current distribution of all seabird species breeding in the Cabo Verde archipelago, updated their relative abundance, investigated their inland habitat preferences, and reviewed their threats. Currently, the breeding seabird community in Cabo Verde is composed of Bulwer’s Petrel Bulweria bulwerii, White-faced Storm-petrel Pelagodroma marina aedesorum, Cape Verde Shearwater Calonectris edwardsii, Cape Verde Storm-petrel Hydrobates jabejabe, Cape Verde Petrel Pterodroma feae, Boyd's Shearwater Puffinus lherminieri boydi, Brown Booby Sula leucogaster, and Red-billed Tropicbird Phaethon aethereus. One breeding species is currently extinct, the Magnificent Frigatebird Fregata magnificens. The relative abundance of Cape Verde Shearwater, Boyd’s Shearwater, Cape Verde Petrel, and Cape Verde Storm-petrel was determined from counts of their nocturnal calls in Santo Antão, São Vicente, Santa Luzia, Branco, Raso and São Nicolau. Cape Verde Petrel occurred only on mountainous islands (Santo Antão, São Nicolau, Santiago, and Fogo) from mid-to high elevations. Larger species such as the Cape Verde Shearwater and Boyd’s Shearwater exhibited a wider distribution in the archipelago, occurring close to the coastline but at lower densities on populated islands. Small procellariforms such as the Cape Verde Storm-petrel occurred at high densities only on rat-free islets and in steep areas of main islands where introduced cats and rats are unlikely to occur. The main threats to seabird populations in Cabo Verde range from predation by introduced predators, habitat alteration or destruction, and some residual human persecution.
The religious/spiritual beliefs and needs of cancer survivors who underwent cancer-directed surgery
Authors: Palmer Kelly Elizabeth , Paredes Anghela Z. , DiFilippo Stephanie , Hyer Madison , Tsilimigras Diamantis I. , Rice Daniel , Bae Junu , Pawlik Timothy M.
Published: August 2020

Objective

We sought to characterize patients’ preferences for the role of religious and spiritual (R&S) beliefs and practices during cancer treatment and describe the R&S resources desired by patients during the perioperative period.

Method

A cross-sectional survey was administered to individuals who underwent cancer-directed surgery. Data on demographics and R&S beliefs/preferences were collected and analyzed.

Results

Among 236 participants, average age was 58.8 (SD = 12.10) years; the majority were female (76.2%), white (94.1%), had a significant other or spouse (60.2%), and were breast cancer survivors (43.6%). Overall, more than one-half (55.9%) of individuals identified themselves as being religious, while others identified as only spiritual (27.9%) or neither (16.2%). Patients who identified as religious wanted R&S integrated into their care more often than patients who were only spiritual or neither (p < 0.001). Nearly half of participants (49.6%) wanted R&S resources when admitted to the hospital including the opportunity to speak with an R&S leader (e.g., rabbi; 72.1%), R&S texts (64.0%), and journaling materials (54.1%). Irrespective of R&S identification, 68.0% of patients did not want their physician to engage with them about R&S topics.

Significance of results

Access to R&S resources is important during cancer treatment, and incorporating R&S into cancer care may be especially important to patients that identify as religious. R&S needs should be addressed as part of the cancer care plan.
Dynamic behavioral modeling of RF power amplifiers based on decomposed piecewise machine learning technique
Authors: Cai Jialin , King Justin B. , Yu Chao , Pan Baicao , Sun Lingling , Liu Jun
Published: August 2020

Multi-device radio frequency power amplifiers (PAs) often exhibit strongly non-linear behavior in combination with long-term memory effects, leading to an extremely challenging model development cycle. This paper presents a new, dynamic, behavioral modeling technique, based on a combination of the real-valued decomposed piecewise method and concepts from the field of machine learning. The underlying theory of the proposed modeling technique is provided, along with a detailed modeling procedure. Experimental results show that the proposed decomposed piecewise support vector regression (SVR) model leads to significant performance improvements when compared with standard SVR models for both single transistor and multi-transistor PAs. Different model thresholds are used to test the proposed model performance for both PA types. For the single-transistor PA, modeled using only one partition, an approximately 10 dB normalized mean square error (NMSE) reduction is seen when compared with the standard SVR model. For the same PA, when utilizing two partitions, the reduction improves to 14 dB. When applied to a multi-device Doherty PA, the NMSE between model and measurement data is −50 dB, representing more than 10 dB improvement compared with the standard SVR model.
Lycopene hampers lung injury due to skeletal muscle ischemia-reperfusion in rat model
Authors: Kirisci Mehmet , Guneri Bulent , Seyithanoglu Muhammed , Kazanci Ulku
Published: August 2020

Abstract. This study investigates lycopene’s preventive efficacy in skeletal muscle ischemia-reperfusion (I/R) induced lung injury. Thirty-two rats were randomly assigned to control group, lycopene group, I/R group and I/R + lycopene group. In the lycopene and I/R + lycopene groups, the rats initially received 10 mg/kg/day lycopene orally for 15 days. Then, dissection around the abdominal aorta was performed in all rats under general anesthesia. The aorta was clamped at the infrarenal level in the I/R group and I/R + lycopene group for two hours before two hours of reperfusion. The mean serum levels of malondialdehyde (53.0 ± 20.14 nmol/mL) and superoxide dismutase (1.03 ± 0.16 U/mL) were higher and lower in the I/R group than the other three groups, respectively (p < 0.001). The mean serum IMA level of I/R + lycopene group (0.42 ± 0.04 abs/u) was lower than the I/R group (0.47 ± 0.04 abs/u) (p = 0.015). The mean tissue malondialdehyde levels of I/R group (69.10 ± 11.55 nmol/mL) and I/R + lycopene group (68.36 ± 21.17 nmol/mL) were high compared to the control group (49.87 ± 6.52 nmol/mL) and lycopene group (47.82 ± 4.44 nmol/mL) (p = 0.002). The mean tissue glutathione peroxidase (p < 0.001) and superoxide dismutase (p = 0.001) levels of I/R group (121.81 ± 43.59 nmol/mL and 25.17 ± 8.69 U/mL) were low compared to the control group (236.12 ± 18.01 nmol/mL and 46.30 ± 5.17 U/mL), lycopene group (227.52 ± 16.92 nmol/mL and 45.82 ± 4.02 U/mL), and I/R + lycopene group (176.02 ± 24.27 nmol/mL and 35.20 ± 4.85 U/mL). The histopathological analyses of I/R + lycopene group indicated less significant changes than the control group. Tissue damage in the I/R + lycopene group was less prominent than the I/R group. These findings suggest oral lycopene supplementation as a promising prevention against skeletal muscle I/R caused lung injury.
Machine Learning Technique Using the Signature Method for Automated Quality Control of Argo Profiles
Authors: Sugiura Nozomi , Hosoda Shigeki
Published: August 2020

A profile from the Argo ocean observation array is a sequence of three‐dimensional vectors composed of pressure, salinity, and temperature, appearing as a continuous curve in three‐dimensional space. The shape of this curve is faithfully represented by a path signature, which is a collection of all the iterated integrals. Moreover, the product of two terms of the signature of a path can be expressed as the sum of higher‐order terms. As a result of this algebraic property, a nonlinear function of the profile shape can always be represented by a weighted linear combination of the iterated integrals, which enables machine learning of a complicated function of the profile shape. In this study, we performed supervised learning for existing Argo data with quality control flags by using the signature method and demonstrated the estimation performance by cross validation. Unlike rule‐based approaches, which require several complicated and possibly subjective rules, this method is simple and objective in nature because it relies only on past knowledge regarding the shape of profiles. This technique is critical for realizing automatic quality control for Argo profile data.
Impact of Assimilation of Moored Velocity Data on Low‐Frequency Current Estimation in Northwestern Tropical Pacific
Authors: Liu Danian , Wang Fan , Zhu Jiang , Wang Dongxiao , Wang Jianing , Xie Qiang , Shu Yeqiang
Published: August 2020

This study investigates the impact of assimilation of Northwestern Tropical Pacific Ocean (NWTPO) moored currents observation system on low‐frequency (over a period of more than 90 days) current estimation. A low‐frequency scale‐selective ensemble optimal interpolation (EnOI) scheme is designed to assimilate the horizontally sparse moored currents into an eddy‐permitting ocean model. In this assimilation scheme, low‐frequency current signals are selected by removing intraseasonal signals in both observation and ensemble data, and a horizontal spatial filter is implemented to match the model forecast to the low‐frequency ensemble and observation. The assimilation of currents efficiently resolves simulated low‐frequency current displacements, especially for the Equatorial Undercurrent (EUC), the North Equatorial Countercurrent (NECC), and the North Equatorial Current (NEC). More realistic intensities of the NWTPO low‐frequency currents are also reproduced. With respect to the moored velocity profiles, the root‐mean‐square error (RMSE) of the simulated low‐frequency zonal velocity above a 500‐m depth is reduced from 10.9 to 5.8 cm/s using this low‐frequency EnOI scheme. The low‐frequency variation of NWTPO currents is reproduced by correcting the structures of different baroclinic modes. The increments of zonal velocities mainly correspond to the first baroclinic mode for the NECC and NEC, while for the EUC, they correspond to the leading three and higher‐order baroclinic modes. The improvements of the simulated stratification and pressure gradient remark the role of the assimilation of moored currents in adjusting available potential energy.
Interdecadal Variation and Causes of Drought in Northeast China in Recent Decades
Authors: Chen Dong , Gao Ya , Sun Jianqi , Wang Huijun , Ma Jiehua
Published: August 2020

This paper focuses on the interdecadal variation in drought in Northeast China (NEC) in recent decades. Two dry and wet periods have occurred in the past 61 years (1950–2010). The mechanism underlying the interdecadal variation in drought in NEC is further analyzed; the results indicate that the direct cause is the interdecadal change of the Okhotsk High (OH). A strong (weak) OH is conducive (detrimental) to the convergence of cold air transported by northeast cold vortex and water vapor from the east of NEC, eventually leading to an increase (decrease) in precipitation. Furthermore, we seek to understand why OH displays such an interdecadal variation. The interdecadal increases and decreases in sea ice in the Barents Sea and the Kara Sea explain most of the interdecadal change of the OH. When more sea ice is present in this area, more energy is transferred eastward from the sea ice area to Northeast Asia, weakening the OH; in contrast, less sea ice strengthens the OH. Sensitivity simulations by Community Atmosphere Model, version 4 (CAM4) using sea ice forcing in the Barents Sea and the Kara Sea yield similar results to the observed data, further confirming our conclusion. The results of this paper provide a new understanding of the interdecadal variation in drought in NEC, and it may help to improve our ability to predict drought and provide early warning in the future.
Basal Channel Evolution on the Getz Ice Shelf, West Antarctica
Authors: Chartrand A. M. , Howat I. M.
Published: August 2020

Ice shelves regulate the ice‐ocean boundary by buttressing the flux of grounded ice into the ocean and are vulnerable to basal melt, which can lead to ice‐shelf thinning and loss of buttressing. Localized, enhanced basal melt can form basal channels, which may impact ice‐shelf stability. Here we investigate the evolution of the Getz Ice Shelf Basal Channel (GISBC) in West Antarctica using a novel suite of geophysical data, including Reference Elevation Model of Antarctica (REMA) digital elevation models, ICESat‐1 and ‐2 altimetry, Operation IceBridge altimetry and radar, and InSAR‐derived ice flow velocities. We describe basal‐channel and ice‐shelf change in both Eulerian and Lagrangian frameworks and document changes in the channel's shape and its lateral motion and estimate basal melting. We find a high degree of spatial and temporal variability in GISBC evolution, with several locations of active basal incision. Incision occurs at rates of up to 22 m a−1 at the head of the channel, which is extending toward the grounding line at a rate of ~1 km a−1. Freeboard heights over areas of rapid basal incision are out of hydrostatic equilibrium. The GISBC is also migrating to the northwest, perpendicular to the northeasterly ice flow direction, at an average rate of 70–80 m a−1. The spatiotemporal variability of evolution of the GISBC motivates further characterization of basal channels and their impact on ice‐shelf stability, so that these effects may more readily be incorporated in ice‐ocean models predicting ice flow and sea‐level rise.
Regional‐Scale Investigation of Preconditioning Factors of Rock Slope Instabilities in NW Bhutan
Authors: Dini Benedetta , Aaron Jordan , Manconi Andrea , De Palezieux Larissa , Leith Kerry , Loew Simon
Published: August 2020

We present a new inventory of large rock slope instabilities and an extensive structural data set for northwestern Bhutan. Our data set is largely based on satellite observations, such as optical images and high‐resolution digital surface models, complemented with field observations. Kinematic analyses over seven different structural domains recognized in the study region were carried out to investigate structural control over the landslide distribution at a regional scale. In order to account for the sampling heterogeneity in the different data sets, a weighting system to the structural data is proposed. The results show that structural control exists in five out of seven domains, with foliation strongly influencing the sliding mechanisms. A lithological control appears also evident, with sedimentary rocks showing the highest landslide densities in the region. This study demonstrates how methodologies built on remote sensing data are suitable to investigate landslide predisposition at regional scales especially in largely inaccessible areas.
Characteristics of Aerosol WSI With High‐Time‐Resolution Observation Over Arctic Ocean
Authors: Yu Congcong , Yan Jinpei , Zhang Honghai , Lin Qi , Zheng Hongguo , Zhong Xinlin , Zhao Suli , Zhang Miming , Zhao Shuhui , Li Xiaojun
Published: August 2020

In the current study, the characteristics of aerosol water‐soluble ions (WSI) were investigated via high‐time‐resolution observations as part of the nineth Chinese National Arctic Research Expedition (CHINARE) in 2018. WSI, including Cl−, SO42−, NO3−, NO2−, F−, Br−, Na+, NH4+, K+, Ca2+, Mg2+, and Methanesulfonic acid (MSA−), were measured using an online ion chromatography system deployed on the Xuelong research vessel. Moreover, aerosol particle sources were analyzed in order to clarify the impacts of marine emissions and anthropogenic sources on atmospheric aerosols in the Arctic Ocean. Sea salt ions (Na+ and Cl−) were observed to be the most dominant compounds, accounting for 53.5% of the total WSI, followed by the secondary ions (SO42−, NH4+, and NO3−), which accounted for 36.0%. Furthermore, similar spatial distributions of MSA− and SO42− were observed during the measurement period. High levels of Na+ were observed in the areas close to the land and Central Arctic Ocean, attributed to wind speed. In the open ocean, NH4+ and NO3− concentrations were extremely low, however, high levels of NH4+ and NO3− were observed in the coastal area close to Alaska and Russia. This indicates that these aerosol particles were influenced by the anthropogenic sources in these regions. In addition, mean fluxes of NO3− and NH4+ were determined as 42 ± 41 and 347 ± 166 μg m−2 day−1 in the Arctic Ocean, respectively.
Remote Sensing of Algal Blooms Can Improve Health and Save Money
Authors: Shultz David
Published: August 2020

Using satellites to detect cyanobacterial algal blooms can foster faster decision-making that reduces harm to public health as well as associated costs.
Intraseasonal Surface Salinity Variability and the MJO in a Climate Model
Authors: Zhu Jieshun , Kumar Arun , Wang Wanqiu
Published: August 2020

Due to the sparsity of ocean observations, understanding inconsistencies exist even in qualitative respect about the mechanisms of intraseasonal sea surface salinity (SSS) over the Indo‐Pacific basin. In this study, a quantitative diagnostic of salinity/freshwater budgets related to the Madden‐Julian oscillation (MJO) was conducted based on model simulations. The model applied is a modified version of the NCEP Climate Forecast System, version 2. The application of a coupled model other than ocean‐only models is one of the unique aspects of this study. The model modifications resulted in a more realistic MJO simulation and a better simulation of intraseasonal SSS variability as validated against the Aquarius estimates. The mechanisms of the MJO‐related SSS variability are further explored by conducting a salinity budget analysis over the mixed layer. The analysis indicates a strong spatial variation of dominant physical processes controlling the local SSS variability. For example, while the role of surface fluxes dominates in the western Indian basin, oceanic advection plays an important role in the eastern Indian and western Pacific oceans.
In Situ Investigations of Dust Above the Lunar Terminator at the Chang'E‐3 Landing Site in the Mare Imbrium
Authors: Li Detian , Wang Yi , Zhang He , Wang Xiaojun , Wang Yongjun , Sun Zezhou , Zhuang Jianhong , Li Cunhui , Chen Liping , Zhang Haiyan , Zou Xin , Zong Chao , Lin Hongyu , Ma Jinan , Li Xiongyao , Cui Xinyu , Yao Rijian , Wang Xilai , Gao Xin , Yang Shengsheng , Wang Xianrong , Zhang Biao
Published: August 2020

It was suspected that the horizon glow observed over the lunar terminator was caused by electrostatically levitated dust particles, but do high concentrations of dust particles really exist over the lunar terminator? This is an important question that cannot be answered even today. In fact, no in situ investigations about the lunar dust have been conducted on lunar surface since Apollo. Here we first report in situ investigations of lunar dust at Chang'E‐3 (CE‐3) landing site using solar cell probe (SCP). The results show that, different from Apollo's observation, the short‐circuit current of SCP did not decrease sharply during the first several lunations except the first lunation, indicating the recently developed minimalist qualitative model of sunrise‐driven dust transport might not be applicable at the geologically young CE‐3 landing site. In addition, within detector's detection limit, no abrupt changes in dust concentration were observed above the sharp sunlight/shadow boundaries on lunar surface.
Liquid‐Vapor Coexistence and Critical Point of Mg2SiO4 From Ab Initio Simulations
Authors: Townsend Joshua P. , Shohet Gil , Cochrane Kyle R.
Published: August 2020

Hypervelocity impact‐driven vaporization is characteristic of late‐stage planet formation. Yet the behavior and properties of liquid‐vapor mixtures of planetary materials of interest are typically unknown. Multiphase equations of state used in hydrodynamic simulations of planet impacts therefore lack reliable data for this important phenomenon. Here, we present the first constraints on the liquid‐vapor critical point and coexistence phase boundary of Mg2SiO4 computed from ab initio molecular dynamics simulations. We found that the vapor is depleted in magnesium and enriched in silica and oxygen, while the coexisting liquid is enriched in magnesium and depleted in oxygen, from which we infer vaporization is incongruent. The critical point was estimated from an equation of state fit to the data. The results are in line with recent calculations of MgSiO3 and together confirm that extant multiphase equation of state (EOS) models used in planetary accretion modeling significantly underestimate the amount of supercritical material postimpact.
Modes of Propagation of Continental Breakup and Associated Oblique Rift Structures
Authors: Jourdon Anthony , Le Pourhiet Laetitia , Mouthereau Frédéric , May Dave
Published: August 2020

V‐shaped oceanic propagators are widespread around the world. Their geometry combined with magnetic anomalies associated with their opening shows at the first order that ridge propagation in the third dimension occurs by pulses. In this study we use 3D thermomechanical numerical models to show how oblique kinematic boundary conditions control both the intracontinental rift development and the oceanic ridge propagation. To do so, we apply a shortening velocity boundary condition in the direction perpendicular to the extension for “strong” and “weak” crustal rheologies. Numerical model results highlight the finding that three ridge propagation modes can occur. For low out‐of‐plane velocities (12% to 15% of the extension rate), the ridge propagation is fast (>1.5 cm year−1) and straight. Higher shortening velocities (15% to 17%) lead to a ridge propagation by pulses alternating between fast propagation (~1.5 cm year−1) and stalling phases. Finally, for higher velocities (17% to 20%) a ridge jump propagation mode occurs, localizing a new spreading center between 100 and 200 km far from the initial ridge. We also show that ridge propagation phases are associated with dip‐slip‐dominated deformation, while stalling phases are dominated by strike‐slip deformation. These deformation regimes are marked by structure reorientation, while kinematic boundary conditions remain constant. We discuss these results in terms of plate tectonic reconstructions and regional geological studies.