bluuebunny/crossref_metadata_2025 huggingface dataset:
H2Ti3O7 Nanotubes Decorated with Silver Nanoparticles for Photocatalytic Degradation of Atenolol
Authors: Hinojosa-Reyes Mariana , Camposeco-Solís Roberto , Ruiz Facundo , Niño Martínez Nereyda , Rodríguez González Vicente , Compeán-Jasso M. E.
Published: June 2017

The photocatalytic degradation/adsorption process of the β-blocker atenolol (ATL) under UV irradiation is described using two types of silver decorated catalysts: silver/titania and silver/titanates. The silver ions were reduced on the surface of TiO2-P25-Degussa using gallic acid. Silver/titanates were prepared by a microwave-assisted hydrothermal method using the silver/titania as the starting material to obtain the hydrogen titanate (H2Ti3O7) structure with tubular morphology. These materials were characterized by X-ray diffraction, UV-Vis spectroscopy, N2 physisorption, temperature programmed reduction, TEM, and FTIR spectroscopy. During the photocatalytic process, the ATL molecules were completely converted to amino-diol byproducts. It is the first time that these materials have been applied during the photocatalytic process in the degradation of pharmaceuticals products. The success of the silver nanoparticles (2 nm) consists of the homogeneous distribution over the surface of titanate nanotubes inhibiting the hole/electron recombination promoting the oxidation process. The Ag@H2Ti3O7 with a concentration of silver as 1.0% shows the highest adsorption/degradation of ATL than the Ag@TiO2 and the P25-Degussa. The great performance in the reuse test consists in the strong attachment of the silver nanoparticles on the titanium surface that inhibits the silver lixiviation during the photocatalytic tests.
Phytochemistry and Pharmacological Studies of Citrus macroptera: A Medicinal Plant Review
Authors: Aktar Koly , Foyzun Tahira
Published: June 2017

Citrus macroptera (family Rutaceae), commonly known as Sat Kara, is a pharmacologically diverse medicinal plant. Various parts of this plant, specifically fruit, have an immense range of medicinal uses in folk medicine directed for a number of ailments. A plethora of active phytochemical constituents of this plant have been revealed so far, namely, limonene, beta‐caryophyllene, beta‐pinene, geranial edulinine, ribalinine, isoplatydesmine, and so forth. Several studies demonstrated the exploration of pharmacological potential of various parts such as fruits, leaves, and stems of C. macroptera as antioxidant, cytotoxic, antimicrobial, thrombolytic, hypoglycemic, anxiolytic, antidepressant, cardioprotective, and hepatoprotective. Furthermore, inhibition of in vitro α‐amylase, inhibition of paracetamol induced hepatotoxicity, and potentiation of brain antioxidant enzyme are also ascertained. In present review, comprehensive study focused on knowledge regarding several phytopharmacological activities of Citrus macroptera has been described.
Glycerol-3-phosphate Acyltransferase 1 Promotes Tumor Cell Migration and Poor Survival in Ovarian Carcinoma
Authors: Marchan Rosemarie , Büttner Bettina , Lambert Jörg , Edlund Karolina , Glaeser Iris , Blaszkewicz Meinolf , Leonhardt Gregor , Marienhoff Lisa , Kaszta Darius , Anft Moritz , Watzl Carsten , Madjar Katrin , Grinberg Marianna , Rempel Eugen , Hergenröder Roland , Selinski Silvia , Rahnenführer Jörg , Lesjak Michaela S. , Stewart Joanna D. , Cadenas Cristina , Hengstler Jan G.
Published: June 2017

Glycerophosphodiesterase EDI3 (GPCPD1; GDE5; GDPD6) has been suggested to promote cell migration, adhesion, and spreading, but its mechanisms of action remain uncertain. In this study, we targeted the glycerol-3-phosphate acyltransferase GPAM along with choline kinase-α (CHKA), the enzymes that catabolize the products of EDI3 to determine which downstream pathway is relevant for migration. Our results clearly showed that GPAM influenced cell migration via the signaling lipid lysophosphatidic acid (LPA), linking it with GPAM to cell migration. Analysis of GPAM expression in different cancer types revealed a significant association between high GPAM expression and reduced overall survival in ovarian cancer. Silencing GPAM in ovarian cancer cells decreased cell migration and reduced the growth of tumor xenografts. In contrast to these observations, manipulating CHKA did not influence cell migration in the same set of cell lines. Overall, our findings show how GPAM influences intracellular LPA levels to promote cell migration and tumor growth. Cancer Res; 77(17); 4589–601. ©2017 AACR.
Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells
Authors: Zarei Mahsa , Lal Shruti , Parker Seth J. , Nevler Avinoam , Vaziri-Gohar Ali , Dukleska Katerina , Mambelli-Lisboa Nicole C. , Moffat Cynthia , Blanco Fernando F. , Chand Saswati N. , Jimbo Masaya , Cozzitorto Joseph A. , Jiang Wei , Yeo Charles J. , Londin Eric R. , Seifert Erin L. , Metallo Christian M. , Brody Jonathan R. , Winter Jordan M.
Published: June 2017

Cancer aggressiveness may result from the selective pressure of a harsh nutrient-deprived microenvironment. Here we illustrate how such conditions promote chemotherapy resistance in pancreatic ductal adenocarcinoma (PDAC). Glucose or glutamine withdrawal resulted in a 5- to 10-fold protective effect with chemotherapy treatment. PDAC xenografts were less sensitive to gemcitabine in hypoglycemic mice compared with hyperglycemic mice. Consistent with this observation, patients receiving adjuvant gemcitabine (n = 107) with elevated serum glucose levels (HgbA1C > 6.5%) exhibited improved survival. We identified enhanced antioxidant defense as a driver of chemoresistance in this setting. ROS levels were doubled in vitro by either nutrient withdrawal or gemcitabine treatment, but depriving PDAC cells of nutrients before gemcitabine treatment attenuated this effect. Mechanistic investigations based on RNAi or CRISPR approaches implicated the RNA binding protein HuR in preserving survival under nutrient withdrawal, with or without gemcitabine. Notably, RNA deep sequencing and functional analyses in HuR-deficient PDAC cell lines identified isocitrate dehydrogenase 1 (IDH1) as the sole antioxidant enzyme under HuR regulation. HuR-deficient PDAC cells lacked the ability to engraft successfully in immunocompromised mice, but IDH1 overexpression in these cells was sufficient to fully restore chemoresistance under low nutrient conditions. Overall, our findings highlight the HuR–IDH1 regulatory axis as a critical, actionable therapeutic target in pancreatic cancer. Cancer Res; 77(16); 4460–71. ©2017 AACR.
MAPK Signaling and Inflammation Link Melanoma Phenotype Switching to Induction of CD73 during Immunotherapy
Authors: Reinhardt Julia , Landsberg Jennifer , Schmid-Burgk Jonathan L. , Ramis Bartomeu Bibiloni , Bald Tobias , Glodde Nicole , Lopez-Ramos Dorys , Young Arabella , Ngiow Shin Foong , Nettersheim Daniel , Schorle Hubert , Quast Thomas , Kolanus Waldemar , Schadendorf Dirk , Long Georgina V. , Madore Jason , Scolyer Richard A. , Ribas Antoni , Smyth Mark J. , Tumeh Paul C. , Tüting Thomas , Hölzel Michael
Published: June 2017

Evolution of tumor cell phenotypes promotes heterogeneity and therapy resistance. Here we found that induction of CD73, the enzyme that generates immunosuppressive adenosine, is linked to melanoma phenotype switching. Activating MAPK mutations and growth factors drove CD73 expression, which marked both nascent and full activation of a mesenchymal-like melanoma cell state program. Proinflammatory cytokines like TNFα cooperated with MAPK signaling through the c-Jun/AP-1 transcription factor complex to activate CD73 transcription by binding to an intronic enhancer. In a mouse model of T-cell immunotherapy, CD73 was induced in relapse melanomas, which acquired a mesenchymal-like phenotype. We also detected CD73 upregulation in melanoma patients progressing under adoptive T-cell transfer or immune checkpoint blockade, arguing for an adaptive resistance mechanism. Our work substantiates CD73 as a target to combine with current immunotherapies, but its dynamic regulation suggests limited value of CD73 pretreatment expression as a biomarker to stratify melanoma patients. Cancer Res; 77(17); 4697–709. ©2017 AACR.
Clinical Pathways: Recommendations for Putting Patients at the Center of Value-Based Care
Authors: Abrahams Edward , Balch Alan , Goldsmith Patricia , Kean Marcia , Miller Amy M. , Omenn Gilbert , Sonet Ellen , Sprandio John , Tyne Courtney , Westrich Kimberly
Published: June 2017

Two major trends that have been affecting the provision of oncology care in the United States are a shift from volume-based to value-based care and a push toward patient-centered healthcare. However, these two trends are not always completely aligned with each other. Value-based payment models, including clinical pathways, are one strategy being implemented by oncology stakeholders to help encourage the uptake of value-based oncology care. If structured with the patient in mind, they can improve quality of care for patients with cancer, decrease inappropriate care while enabling appropriate personalization of care, and constrain rising prices by demanding a stronger link between cost and value. If not structured appropriately, they can limit patient choice, impede access to innovative treatments, and encourage one-size-fits-all oncology care. Clin Cancer Res; 23(16); 4545–9. ©2017 AACR.
Cardiovascular Oncologic Emergencies
Authors: Shenoy Sundeep , Shetty Safal , Lankala Shilpa , Anwer Faiz , Yeager Andrew , Adigopula Sasikanth
Published: June 2017

Oncologic emergencies can present either as a progression of a known cancer or as the initial presentation of a previously undiagnosed cancer. In most of these situations, a very high degree of suspicion is required to allow prompt assessment, diagnosis, and treatment. In this article, we review the presentation and management of cardiovascular oncologic emergencies from primary and metastatic tumors of the heart and complications such as pericardial tamponade, superior vena cava syndrome, and hyperviscosity syndrome. We have included the cardiovascular complications from radiation therapy, chemotherapeutic agents, and biologic agents used in modern cancer treatment.
Greater Real-Life Diagnostic Efficacy of Allergen Molecule-Based Diagnosis for Prescription of Immunotherapy in an Area with Multiple Pollen Exposure
Authors: Saltabayeva Ulbosin , Garib Victoria , Morenko Marina , Rosenson Rafail , Ispayeva Zhanat , Gatauova Madina , Zulus Loreta , Karaulov Alexander , Gastager Felix , Valenta Rudolf
Published: June 2017

Background: Allergen molecule-based diagnosis has been suggested to facilitate the identification of disease-causing allergen sources and the prescription of allergen-specific immunotherapy (AIT). The aim of the current study was to compare allergen molecule-based IgE serology with allergen extract-based skin testing for the identification of the disease-causing allergen sources. The study was conducted in an area where patients are exposed to pollen from multiple sources (trees, grasses, and weeds) at the same time to compare the diagnostic efficiency of the 2 forms of diagnosis. Methods: Patients from Astana, Kazakhstan, who suffered from pollen-induced allergy (n = 95) were subjected to skin prick testing (SPT) with a local panel of tree pollen, grass pollen, and weed pollen allergen extracts and IgE antibodies specific for marker allergen molecules (nArt v 1, nArt v 3, rAmb a 1, rPhl p 1, rPhl p 5, rBet v 1) were measured by ImmunoCAP. Direct and indirect costs for diagnosis based on SPT and marker allergen-based IgE serology as well as direct costs for immunotherapy depending on SPT and serological test results were calculated. Results: The costs for SPT-based diagnosis per patient were lower than the costs for allergen molecule-based IgE serology. However, allergen molecule-based serology was more precise in detecting the disease-causing allergen sources. A lower number of immunotherapy treatments (n = 119) was needed according to molecular diagnosis as compared to extract-based diagnosis (n = 275), which considerably reduced the total costs for diagnosis and for a 3-year treatment from EUR 1,112.30 to 521.77 per patient. Conclusions: The results from this real-life study show that SPT is less expensive than allergen molecule-based diagnostic testing, but molecular diagnosis allowed more precise prescription of immunotherapy which substantially reduced treatment costs and combined costs for diagnosis and treatment.
Aspectos da Tectônica Ativa em Bordas Cratônicas: Interpretações com Base em Dados Geomorfométricos na Região das Altas Cristas Quartzíticas da Zona da Mata Mineira
Authors: Silva Felipe Rodrigues , Marques Neto Roberto , Moreira Juliana Alves , Rodrigues Elver Lonie Nunes
Published: June 2017

Nos últimos anos, as áreas sob a influência mais direta do rifte continental do sudeste brasileiro tem sido alvo de estudos pautados no campo temático da neotectônica, se integrando ao rol de trabalhos que vem sendo levados a efeito em outras regiões do país. Na presente oportunidade, são divulgados resultados provenientes da aplicação de técnicas morfométricas voltadas para a diferenciação entre controles passivos e ativos na região das altas cristas quartzíticas da Zona da Mata Mineira, para a qual ainda faltam estudos mais específicos. Com a aplicação integrada entre o índice Relação Declividade x Extensão do Canal (RDE) e a mensuração e representação cartográfica das superfícies de base, associados a controle de campo e interpretação de produtos de sensoriamento remoto, constatou-se controle morfotectônico ativo na evolução do relevo, e que vem engendrando substanciais reorganizações nas formas e processos de superfície.
Impacto das Tempestades de 2016 em Orla Urbanizada: Arco Praial de Piratininga, Niterói – RJ
Authors: Pereira Thiago Gonçalves , Oliveira Filho Silvio Roberto de , Moraes Clara Pinheiro Reis de Araujo , Lessa Ana Claudia Prudêncio
Published: June 2017

O presente trabalho trata de estudos de morfodinâmica praial em orla com elevado grau de urbanização, no município de Niterói, RJ. A perspectiva se concentra nos impactos de tempestades que ocorreram em 2016, onde dois eventos extremos causaram erosão total do estoque emerso de sedimentos em alguns trechos da praia e destruição parcial do calçadão e um quiosque da orla. A partir de levantamentos topográficos de perfis de praia, cálculo do volume de sedimentos e análise dos parâmetros oceanográficos obtidos em modelo GFS (Global Forecast System), foi possível retratar o comportamento dos estoques emersos e sua variação nas duas maiores tempestades do ano, em abril e junho. Os resultados mostraram forte impacto erosivo no setor leste no primeiro evento, sem interferência significativa no setor oeste, e uma erosão mais homogênea em todo o arco na segunda tempestade. Em ambas situações a incidência de ondas foi de direção SSW e altura significativa de 3m ou superior. Após o efeito erosivo, foi identificado um comportamento resiliente em quatro dos cinco pontos de monitoramento, onde houve rápida incorporação de sedimentos após o decaimento de energia das ondas. Apenas o setor extremo-leste apresentou uma recuperação mais lenta ou incompleta, em relação ao ano anterior à ocorrência desses eventos extremos.
Geografia Física nas Provas do Enem: Relação Interdisciplinar com as Ciências da Natureza
Authors: Da Silva Coutinho Edlane Cruz , Franco Gustavo Barreto , Amorim Raul Reis
Published: June 2017

O presente trabalho faz uma análise crítica sobre a Geografia no Exame Nacional do Ensino Médio (ENEM), tendo como viés a abordagem interdisciplinar. Tem-se como proposta um estudo analítico relacionando a Geografia e a Interdisciplinaridade como recurso para abordagem de conteúdos de forma contextualizada. Para isso, pretende-se analisar de que forma a Geografia aparece nas questões do ENEM, priorizando recursos e os temas que mais aparecem nos enunciados. A metodologia aplicada na pesquisa foi a análise de conteúdo com aplicação do método qualitativo, que, após as análises, originaram dados quantitativos. Os resultados alcançados referem-se às análises das provas aplicadas nos anos de 1998, 1999, 2008, 2009, 2010. A escolha da prova de 1998 se deu pela necessidade de se entender como eram a estrutura inicial e o formato do exame. Como marco das mudanças na aplicação desse exame, a prova de 2009 integrou essa etapa, pois ela passa ser organizada em Áreas do Conhecimento. Os resultados revelaram que há uma valorização na cobrança dos conteúdos geográficos, principalmente no que se refere à Geografia Física. Por outro lado, percebe-se a desvalorização da principal linguagem da Geografia – os mapas, ferramenta tão necessária na espacialização dos fenômenos físicos e sociais. Como resultado parcial, identificou-se que o modelo atual do ENEM proporcionou uma nova fragmentação Geografia Física e Geografia Humana, devido à organização, em que a Geografia Física relaciona-se com as Ciências da Natureza.
Análise Estatística Anual e Mensal das Ondas Atuantes na Costa de Ilhéus (Bahia) Baseada na Reanálise de Série Temporal de 31 Anos do Modelo de Ondas WAVEWATCH III
Authors: Lobo Matheus Santos , Santos Bárbara Savina Silva , Lavenère-Wanderley Ana Amelia De Oliveira
Published: June 2017

Mobilidade e transporte de sedimentos induzidos por ondas são questões importantes em estudos do balanço sedimentar na zona costeira. A falta de dados disponíveis acerca do clima de ondas na costa brasileira dificulta e prejudica o entendimento da dinâmica costeira para o estabelecimento correto das ocupações na zona costeira. Uma série temporal de 31 anos (1979-2009) de parâmetros de ondas (altura significativa, período de pico e direção), obtidos do modelo WAVEWATCH III (NCEP - NOAA), foi analisada estatisticamente, objetivando determinar a tendência central e a variabilidade das informações. O programa R paratabular e avaliar as informações, realizar os cálculos estatísticos e sua exibição gráfica. A análise anual da série temporal indicou a predominância de ondas provenientes de Leste e Sudeste, com alturas variando entre 0.39m e 4.89m. Os períodos médios indicaram a predominância de ondas geradas por vento local (vagas), com valores inferiores a 10 segundos. A influência de ondas geradas em outras regiões do oceano (marulhos) é evidenciada quando considerado o desvio padrão do registro. Os parâmetros tabulados mensalmente indicaram como os mais energéticos os meses de junho, julho, agosto e setembro, que correspondem às estações inverno e primavera.
Relato de Experiência Desenvolvido com Estudantes da NEJA no Ensino de Climatologia em Baixa Grande - Campos Dos Goytacazes/RJ
Authors: Pereira Taísa Das Dores , Lima Maria do Socorro Bezerra de , Silva Maria Gertrudes Alvarez Justi da
Published: June 2017

O ensino de climatologia faz parte do currículo de geografia e é apresentado demonstrando a relação que há entre a superfície terrestre e a atmosfera. O ensino de climatologia estuda a dinâmica, a classificação e a descrição do clima, a ocorrência de fenômenos na atmosfera e sua influência na sociedade. Sua importância se dá à medida que contribui para o desenvolvimento de habilidades fundamentais para o processo de ensino aprendizagem. Este estudo tem como principal objetivo trabalhar o fenômeno meteorológico chuva, através dos conteúdos de aprendizagens nas aulas de geografia da Nova Educação de Jovens e Adultos. As atividades realizadas ocorreram no Colégio Estadual Dr. Barros Barreto, na localidade de Baixa Grande, no município de Campos dos Goytacazes/RJ. Os procedimentos operacionais compreenderam a instalação de uma estação meteorológica móvel na escola, o monitoramento do tempo e o desenvolvimento de atividades e experiências pedagógicas. Os resultados apontam para a defasagem no ensino de disciplinas essenciais, a dificuldade dos alunos de se expressar através da escrita, e a percepção de que é viável utilizar os conteúdos de aprendizagens no ensino de climatologia. Assim, é possível concluir que a valorização dos saberes e os conteúdos de aprendizagens corroboram e auxiliam o processo no ensino de climatologia nas aulas de Geografia.
Cardiometabolic Determinants of Carotid and Aortic Distensibility From Childhood to Early Adulthood
Authors: Mikola Hanna , Pahkala Katja , Niinikoski Harri , Rönnemaa Tapani , Viikari Jorma S.A. , Jula Antti , Juonala Markus , Raitakari Olli T.
Published: June 2017

Children who are obese or have familial hypercholesterolemia have stiffer arteries compared with lean, healthy peers. Limited data are, however, available on the association of cardiometabolic risk markers and arterial distensibility in healthy children, particularly in a longitudinal setting. Therefore, we studied in the prospective STRIP (Special Turku Coronary Risk Factor Intervention Project) comprising healthy, predominantly normal weight participants the association of several cardiometabolic and dietary risk markers with arterial distensibility from childhood to early adulthood. Carotid and aortic distensibility (cdist, adist) was assessed repeatedly with ultrasonography at the age of 11, 13, 15, 17, and 19 years in the longitudinal atherosclerosis prevention study (n
cdist
=420–503, n
adist
=407–476). Data on cardiometabolic risk markers and diet were available since early childhood. In multivariable analyses, body mass index (β=−0.0019 [SE 0.0085];
P
=0.037), systolic blood pressure (β=−0.0025 [SE 0.00065];
P
=0.0001), low-density lipoprotein cholesterol (β=−0.026 [SE 0.012];
P
=0.034), and homeostasis model of insulin resistance (β=−0.048 [SE 0.018];
P
=0.0071) were independently associated with carotid distensibility. Systolic blood pressure (β=−0.0069 [SE 0.00097];
P
<0.0001) and low-density lipoprotein cholesterol (β=−0.039 [SE 0.018];
P
=0.031) associated independently with aortic distensibility. Dietary variables were not independently associated with arterial distensibility. Participants with low arterial distensibility had higher body mass index (
P
cdist
=0.0090,
P
adist
=0.098) and higher systolic (
P
cdist
<0.0001,
P
adist
<0.0001) and diastolic blood pressures (
P
cdist
<0.0001,
P
adist
=0.0002) already from early childhood. Body mass index, blood pressure, low-density lipoprotein cholesterol, and homeostasis model of insulin resistance identified since childhood associate with arterial distensibility in healthy children and adolescents. These data support the relevance of these factors as part of primordial prevention.

Clinical Trial Registration—

URL:
http://www.clinicaltrials.gov
. Unique identifier: NCT00223600.
Blood Pressure and Visit-to-Visit Blood Pressure Variability Among Individuals With Primary Proteinuric Glomerulopathies
Authors: Sethna Christine B. , Meyers Kevin E.C. , Mariani Laura H. , Psoter Kevin J. , Gadegbeku Crystal A. , Gibson Keisha L. , Srivastava Tarak , Kretzler Matthias , Brady Tammy M.
Published: June 2017

Hypertension and blood pressure variability (BPV; SD and average real variability) in primary proteinuric glomerulopathies are not well described. Data were from 433 participants in the NEPTUNE (Nephrotic Syndrome Study Network). Hypertensive BP status was defined as previous history of hypertension or BP ≥140/90 mm Hg for adults/≥95th percentile for children at baseline. BPV was measured in participants with ≥3 visits in the first year. Two-hundred ninety-six adults (43 years [interquartile range, 32–57.8 years], 61.5% male) and 147 children (11 years [interquartile range, 5–14 years], 57.8% male) were evaluated. At baseline, 64.8% of adults and 46.9% of children were hypertensive. Histological diagnosis was associated with hypertensive status in adults (
P
=0.036). In adults, hypertensive status was associated with lower hazard of complete remission (hazard ratio, 0.36; 95% confidence interval, 0.19–0.68) and greater hazard of achieving the composite end point (end-stage renal disease or estimated glomerular filtration rate decline >40%; hazard ratio, 4.1; 95% confidence interval, 1.4–12). Greater systolic and diastolic SD and average real variability were also associated with greater hazard of reaching the composite end point in adults (all
P
<0.01). In children, greater BPV was an independent predictor of composite end point (determined by systolic SD and average real variability) and complete remission (determined by systolic and diastolic average real variability; all
P
<0.05). Hypertensive status was common among adults and children enrolled in NEPTUNE. Differences in hypertensive status prevalence, BPV, and treatment were found by age and histological diagnosis. In addition, hypertensive status and greater BPV were associated with poorer clinical outcomes.
Interhemispheric Binding of Ambiguous Visual Motion Is Associated with Changes in Beta Oscillatory Activity but Not with Gamma Range Synchrony
Authors: Costa Gabriel Nascimento , Duarte João Valente , Martins Ricardo , Wibral Michael , Castelo-Branco Miguel
Published: June 2017

In vision, perceptual features are processed in several regions distributed across the brain. Yet, the brain achieves a coherent perception of visual scenes and objects through integration of these features, which are encoded in spatially segregated brain areas. How the brain seamlessly achieves this accurate integration is currently unknown and is referred to as the “binding problem.” Among the proposed mechanisms meant to resolve the binding problem, the binding-by-synchrony hypothesis proposes that binding is carried out by the synchronization of distant neuronal assemblies. This study aimed at providing a critical test to the binding-by-synchrony hypothesis by evaluating long-range connectivity using EEG during a motion integration visual task that entails binding across hemispheres. Our results show that large-scale perceptual binding is not associated with long-range interhemispheric gamma synchrony. However, distinct perceptual interpretations were found to correlate with changes in beta power. Increased beta activity was observed during binding under ambiguous conditions and originates mainly from parietal regions. These findings reveal that the visual experience of binding can be identified by distinct signatures of oscillatory activity, regardless of long-range gamma synchrony, suggesting that such type of synchrony does not underlie perceptual binding.
Ophiorrhiza debiana (Rubiaceae, Rubioideae), a new species from North-East India
Authors: HAREESH VADAKKOOT SANKARAN , JOE ALFRED , SABU MAMIYIL
Published: June 2017

A new species of Ophiorrhiza is described from Arunachal Pradesh, North-East India. Ophiorrhiza debiana is compared with O. cordata, a Chinese species. Detailed description, distribution, ecology, phenology and relevant taxonomic notes are provided along with colour photographs.
Neoalbatrellus odorus sp. nov. (Albatrellaceae, Russulales) from Southwest China
Authors: CHEN YUAN-YUAN , WANG MIN , ZHANG BO , CUI BAO-KAI
Published: June 2017

We describe herein the Neoalbatrellus odorus sp. nov. accounting on its peculiar morphological features and molecular data. It is characterized by fleshy basidiomata with a deep violet to dark violet pileal surface, which turns blackish blue and glossy after drying. It also has a white pore surface, light violet to bluish violet stipe, simple septate generative hyphae, and thick-walled, non-amyloid basidiospores. The phylogenetic analyses, based on ITS and 28S rDNA sequences of Neoalbatrellus and its related genera, were performed using Maximum Parsimony, Maximum Likelihood and Bayesian Inference, confirming the affiliation of the new species to Neoalbatrellus.
Sageretia liuzhouensis (Rhamnaceae), a new species from Guangxi, China
Authors: YANG YI , ZHANG JIAN-WEN , SUN LU , SUN HANG
Published: June 2017

Sageretia liuzhouensis, a new species discovered in Guangxi Zhuang Autonomous Region, China, is described and illustrated. This species was found growing in sparse forests or thickets on the top of towering limestone hills with sunny, dry habitats. It is very similar to S. camelliifolia in morphology but differs with pubescent inflorescence rachises and charcoal-gray branches, as well as smaller leaves and shorter petioles. The delimitation of this new species is also supported by phylogenetic analyses based on five DNA loci (ITS, ETS, trnL-trnF, psbA-trnH and petA-psbJ). S. camelliifolia is within a clade separated from the new species and S. thea is more closely related to S. subcaudata and S. rugosa than the new species.
Nomenclatural remarks on Magnolia sect. Macrophylla (Magnoliaceae), with description of a new species from North America (Tamaulipas, Mexico)
Authors: GARCÍA-MORALES LECCINUM J. , IAMONICO DUILIO , JIMÉNEZ JESÚS GARCÍA
Published: June 2017

As part of ongoing studies on Magnolia sect. Macrophylla in North America (Mexico), unusual populations from the humid forests of Sierra Madre Oriental (central western Tamaulipas State) were found. They are here formalized as a new species, M. alejandrae. Its morphology, ecology, and conservation status are provided. A morphological comparison with similar species and diagnostic key for the species of M. sect. Macrophylla are also included. The names Magnolia ashei, M. macrophylla, and M. dealbata are lectotypified, respectively, on specimens preserved at NCU, and P and on a Zuccarini illustration. An epitype (at M) was chosen for M. dealbata.
Occurrence of Anafroptilum Kluge 2012 (Ephemeroptera: Baetidae) in Oriental Region
Authors: KLUGE NIKITA J. , NOVIKOVA EUGENIA A.
Published: June 2017

Two new species, Anafroptilum orthostylus sp. n. and Anafroptilum odontostylus sp. n. are described from Thailand based on imagoes reared from larvae. Both new species lack hind wings; larvae of both species have an unusual prominent spine near cercus apex; other characters, especially shape of male imaginal gonostyli and shape of larval tergalii, are quite diverse in these two species. The genus Anafroptilum, hitherto known from the East Palaearctic [as a single species A. kazlauskasi (Kluge 1983)] and from Nearctic [as eight species reported by Jacobus & Wiersema (2014)], is reported from Oriental Region for the first time.
Two new species of Elaphoidella (Copepoda, Harpacticoida) from caves in southern Thailand and a key to the species of Southeast Asia
Authors: WATIROYRAM SANTI , SANOAMUANG LA-ORSRI , BRANCELJ ANTON
Published: June 2017

Elaphoidella paraaffinis sp. nov. and E. ligorae sp. nov. are described from Phra Kayang and Khao Plu caves respectively in southern Thailand. They both belong to Group I sensu Lang (1948). Elaphoidella paraaffinis and E. ligorae are similar to E. affinis Chappuis, 1933 and E. cabezasi Petkovski, 1982 respectively. Elaphoidella paraaffinis differs from E. affinis by (1) its larger sized setae on Exp P5, (2) the absence of an inner seta on Endp P1–P4, (3) fewer setae on P3 Endp-2, and (4) a larger number of ventral spinules on its anal segment. Elaphoidella ligorae differs from E. cabezasi by (1) its serrated posterior margins of urosomites, (2) the presence of strong inner spinules on its caudal ramus, (3) larger sized and a lower number of ventral spinules on its anal segment in male and female respectively, (4) larger sized setae on P5 in female, (5) the presence of an inner seta on Endp-1 P2, and (6) a larger number of setae on Endp-2 P2 in male. An identification key to the Southeast Asian species of the genus Elaphoidella Chappuis, 1929 is provided.
Reclaiming Adolescent Sexuality: Images of Girlhood in Petra Collins’s Babe
Authors: Kamińska Aleksandra
Published: June 2017

Reclaiming Adolescent Sexuality: Images of Girlhood in Petra Collins’s BabeThis paper examines photographs, drawings, collages and other art forms collected in the book Babe, edited by photographer Petra Collins and published by Prestel in 2015. I read the collected artwork as an attempt to present the image of the girl (including her sexuality) from a young woman’s perspective. Babe, which includes works such as photographs of teenagers with visible period blood on the underwear or a to-do list with the goal of never faking another orgasm, asks who a contemporary girl is and how young artists can challenge traditional images of femininity. In my analysis I focus on the excessive use of the color pink in Babe, characterizing the way artists blend innocence with eroticism. I argue that by playing with artifacts of “girlishness,” artists can both expose the absurdity of the image of the girl in popular culture and reclaim symbols of girlhood. I suggest that Collins – despite her ambitions to create an inclusive platform for female artists – does not present a diverse image of girls, who in Babe is still predominantly white and able-bodied. I introduce the potential reading of Babe as a feminist visual manifesto, in reference to the Riot Grrrl movement and the cultural phenomenon of “girl power.” I suggest that the book offers a possibility of exploring the figure of the girl from the perspective of young female artists. Odzyskując młodzieńczą seksualność: wizerunki dziewczyńskości w „Babe” Petry CollinsArtykuł jest analizą fotografii, rysunków, kolaży i innych prac zebranych przez fotografkę Petrę Collins w albumie „Babe", wydanym w 2015 roku przez Prestel. W artykule odczytuję zebrane prace jako szansę zaprezentowania wizerunku dziewczyny (w tym jej seksualności) z perspektywy młodej kobiety. Babe – w której znajdują się zarówno fotografie nastolatek z widoczną krwią menstruacyjną na bieliźnie, jak i zdjęcie listy zadań, na której artystka umieszcza postanowienie, by nigdy więcej nie udawać orgazmu – zadaje pytanie kim dzisiaj jest dziewczyna i w jaki sposób młode artystki mogą kwestionować utarte obrazy kobiecości. Podczas analizy skupiam się na przewadze różu w warstwie wizualnej albumu, ukazując sposób, w jaki artystki łączą pozorną niewinność z erotyzmem. Twierdzę, że poprzez grę z konwencjami „dziewczyńskości” autorki prac mogą zarówno eksponować sztuczność wizerunku młodej kobiety w kulturze popularnej, jak i odzyskiwać symbole dziewczęcości. Sugeruję, że Collins – mimo próby stworzenia inkluzywnej platformy dla artystek – nie oferuje zróżnicowanego obrazu dziewczyny, która w Babe wciąż jest przeważnie biała i pełnosprawna. W odczytaniu Babe jako feministycznego wizualnego manifestu odwołuję się do ruchu Riot Grrrl i fenomenu kulturowego reprezentowanego przez hasło „girl power”. Sugeruję, że album oferuje zgłębienie postaci dziewczyny z punktu widzenia młodych artystek.
The Effect of Cloud Cover on the Meridional Heat Transport: Lessons from Variable Rotation Experiments
Authors: Liu Xiaojuan , Battisti David S. , Roe Gerard H.
Published: June 2017

The question “What determines the meridional heat transport (MHT)?” is explored by performing a series of rotation-rate experiments with an aquaplanet GCM coupled to a slab ocean. The change of meridional heat transport with rotation rate falls into two regimes: in a “slow rotating” regime (rotation rate < 1/2 modern rotation) MHT decreases with increasing rotation rate, whereas in a “fast rotating” regime (rotation rate ≥ 1/2 modern rotation) MHT is nearly invariant. The two-regime feature of MHT is primarily related to the reduction in tropical clouds and increase in tropical temperature that are associated with the narrowing and weakening of the Hadley cell with increasing rotation rate. In the slow-rotating regime, the Hadley cell contracts and weakens as rotation rate is increased; the resulting warming causes a local increase in outgoing longwave radiation (OLR), which consequently decreases MHT. In the fast-rotating regime, the Hadley cell continues to contract as rotation rate is increased, resulting in a decrease in tropical and subtropical clouds that increases the local absorbed shortwave radiation (ASR) by an amount that almost exactly compensates the local increases in OLR. In the fast-rotating regime, the model heat transport is approximately diffusive, with an effective eddy diffusivity that is consistent with eddy mixing-length theory. The effective eddy diffusivity decreases with increasing rotation rate. However, this decrease is nearly offset by a strong increase in the meridional gradient of moist static energy and hence results in a near-constancy of MHT. The results herein extend previous work on the MHT by highlighting that the spatial patterns of clouds and the factors that influence them are leading controls on MHT.
Evaluation of Reanalyzed Precipitation Variability and Trends Using the Gridded Gauge-Based Analysis over the CONUS
Authors: Cui Wenjun , Dong Xiquan , Xi Baike , Kennedy Aaron
Published: June 2017

Atmospheric reanalyses have been used in many studies to investigate the variabilities and trends of precipitation because of their global coverage and long record; however, their results must be properly analyzed and their uncertainties must be understood. In this study, precipitation estimates from five global reanalyses [ERA-Interim; MERRA, version 2 (MERRA2); JRA-55; CFSR; and 20CR, version 2c (20CRv2c)] and one regional reanalysis (NARR) are compared against the CPC Unified Gauge-Based Analysis (CPCUGA) and GPCP over the contiguous United States (CONUS) during the period 1980–2013. Reanalyses capture the variability of the precipitation distribution over the CONUS as observed in CPCUGA and GPCP, but large regional and seasonal differences exist. Compared with CPCUGA, global reanalyses generally overestimate the precipitation over the western part of the country throughout the year and over the northeastern CONUS during the fall and winter seasons. These issues may be associated with the difficulties models have in accurately simulating precipitation over complex terrain and during snowfall events. Furthermore, systematic errors found in five global reanalyses suggest that their physical processes in modeling precipitation need to be improved. Even though negative biases exist in NARR, its spatial variability is similar to both CPCUGA and GPCP; this is anticipated because it assimilates observed precipitation, unlike the global reanalyses. Based on CPCUGA, there is an average decreasing trend of −1.38 mm yr−1 over the CONUS, which varies depending on the region with only the north-central to northeastern parts of the country having positive trends. Although all reanalyses exhibit similar interannual variation as observed in CPCUGA, their estimated precipitation trends, both linear and spatial trends, are distinct from CPCUGA.
Family inclusion in mental health services: Reality or rhetoric?
Authors: Martin Robyn M , Ridley Sophie C , Gillieatt Sue J
Published: June 2017

Background:

Contemporary mental health policies require family inclusion in the design, implementation and evaluation of services.

Materials:

This scoping review considers the factors in mental health practice which either mediate or promote family inclusion. A wide range of factors are reported to obstruct family inclusion, while a smaller number of studies report that meaningful family inclusion rests on a partnership approach which values the input of families and services users.

Discussion:

When it comes to family inclusion, there is a gap between policy and service delivery practice. Changes in service delivery attitudes, values and culture are necessary to meaningfully and systematically include families and service users.
Supra-Segmental Changes in Speech Production as a Result of Spectral Feedback Degradation: Comparison with Lombard Speech
Authors: Casserly Elizabeth D. , Wang Yeling , Celestin Nicholas , Talesnick Lily , Pisoni David B.
Published: June 2017

Perturbations to acoustic speech feedback have been typically localized to specific phonetic characteristics, for example, fundamental frequency (F0) or the first two formants (F1/F2), or affect all aspects of the speech signal equally, for example, via the addition of background noise. This paper examines the consequences of a more selective global perturbation: real-time cochlear implant (CI) simulation of acoustic speech feedback. Specifically, we examine the potential similarity between speakers’ response to noise vocoding and the characteristics of Lombard speech. An acoustic analysis of supra-segmental characteristics in speaking rate, F0 production, and voice amplitude revealed changes that paralleled the Lombard effect in some domains but not others. Two studies of speech intelligibility complemented the acoustic analysis, finding that intelligibility significantly decreased as a result of CI simulation of speaker feedback. Together, the results point to differences in speakers’ responses to these two superficially similar feedback manipulations. In both cases we see a complex, multi-faceted behavior on the part of talkers. We argue that more instances of global perturbation and broader response assessment are needed to determine whether such complexity is present in other feedback manipulations or if it represents a relatively rare exception to the typical compensatory feedback response.
Perception of the Lexical Accent Contrast in One Variety of East Norwegian
Authors: Kelly Niamh E. , Smiljanić Rajka
Published: June 2017

The perception of the lexical pitch accents was examined in the Trøndersk dialect of Norwegian. Based on a production study, a categorization of stimuli with manipulated pitch contours was conducted. The experiment tested which acoustic cues (height and alignment of fundamental frequency (F0) minimum, and alignment of F0 maximum and turning point from maximum to minimum) are necessary for the perception of the tonal contrast. The results are consistent with the production findings in that changes in all of the examined acoustic cues contributed to the shift in accent categorization. The later alignment of the main F0 landmarks (F0 maximum, F0 minimum and turning point from maximum to minimum) induced accent 2 identification. Raising F0 minimum height also led to more accent 2 responses. The analysis of the perception patterns furthermore revealed that the effect of a later alignment of F0 minimum was weak unless combined with a later alignment of the other F0 landmarks, or a higher F0 minimum level, all of which contributed to more accent 2 responses. These results indicate that accent 1 is characterized by an early fall, and accent 2 by a salient initial high tone. Implications of these findings for the phonological analysis of the tonal contrasts in the Trøndersk dialect are also discussed.
Developing Transfer Pride: An Exploration of Critical Race Pedagogy and the Summer Transfer Enrichment Program
Authors: Jain Dimpal , Lucero Iris , Bernal Santiago , Herrera Alfred , Solorzano Daniel
Published: June 2017

Objective: This study examined the critical race pedagogy of the Summer Transfer Enrichment Program (STEP) over a 5-year span and how the curriculum and supplemental academic programming aided in the development of a positive transfer identity for its participants. Method: A mixed method convergent parallel design approach was used to collect quantitative and qualitative data in the forms of surveys and focus groups. Fifty-six students, the majority Latinx, responded to the survey along with 22 students in focus groups. Data were analyzed through descriptive statistics and a reiterative thematic coding process. Results: Students shared how their summer courses and additional workshops and speakers reflected critical race pedagogy, how they experienced racial isolation and discrimination once they transferred to a 4-year campus, and ultimately how they built a strong sense of transfer pride. Conclusion: Based on the study’s findings, we encourage universities and colleges to build a more supportive transfer receptive culture that centralizes race and offers critical pedagogical spaces in its outreach efforts.
Introduction. After the Urban Crisis: New York and the Rise of Inequality
Authors: Chronopoulos Themis , Soffer Jonathan
Published: June 2017

The introduction to this special section argues that the deconstruction of the city’s municipal social democracy was overdetermined by shifts in the global political economy toward increased income inequality and the depoliticization of national economic management. The city’s creditors forced it into an ideologically-motivated program of market discipline that cut its operating budget as the city’s economy financialized, defined by Greta Krippner as “the tendency for profit making in the economy to occur increasingly through financial channels rather than through productive activities.” The city’s leaders believed that their program would revive the city for the middle class. But financialization exacerbated income inequality. In 1970, the top 0.01 percent of earners made fifty times the average income; by 1998, that figure had increased to 250 times the average income. In 2013 Mayor Michael Bloomberg commented that: “If we could get every billionaire around the world to move here, it would be a godsend that would create a much bigger income gap,” which, he argued, was good for the whole city, because it would raise its tax base. The four articles of this section are part of a new and growing body of historical works about New York City since the 1970s that challenge the linear narratives of concepts such as neoliberalism, gentrification, public space, law and order, and resistance by reviewing how ordinary New Yorkers coped with declining infrastructure, services, standards of living, and increasing inequality.
Does Parenteral Nutrition Increase the Risk of Catheter‐Related Bloodstream Infection? A Systematic Literature Review
Authors: Gavin Nicole Clare , Button Elise , Keogh Samantha , McMillan David , Rickard Claire
Published: June 2017

Background: Central venous access devices (CVADs) are used for parenteral nutrition (PN) delivery. We systematically reviewed research‐based publications that reported comparative rates of catheter‐related bloodstream infection (CRBSI) in patients with CVADs who received PN vs those who did not receive PN therapy. Materials and Methods: The literature search included the Cochrane Library, MEDLINE, CINAHL, and PubMed up to July 14, 2015, to identity studies that compared patients with a CVAD who did and did not have PN therapy. Results: Eleven observational studies were identified, comprising 2854 participants with 6287 CVADs. Six studies produced significant results in favor of non‐PN, 4 studies showed no evidence of a difference between PN and non‐PN, and 1 study produced significant results in favor of PN when analyzed per patient with multiple CVADs. Incidence ranged from 0 to 6.6 CRBSIs per 1000 CVAD days in the PN patients and 0.39 to 3.6 CRBSIs per 1000 CVAD days in the non‐PN patients. The Cochrane risk of bias assessment tool for nonrandomized studies of interventions was used. Eight studies were rated as moderate risk of bias, 2 as serious, and 1 as critical. Conclusion: The data presented in this systematic review are not sufficient to establish whether patients receiving PN are more at risk of developing CRBSI than those who do not. Future PN studies needs to adjust for baseline imbalances and improve quality and reporting.
Changing work routines and labour practices of sports journalists in the digital era: a case study of Postmedia
Authors: Daum Evan , Scherer Jay
Published: June 2017

This article contributes to an emerging body of research that examines the transformation of sport, journalism and media practice in the digital era as part of what Raymond Williams has called the ‘long revolution’ of communications, culture and democracy. In so doing, we explore how Canadian sports journalists have attempted to make sense of, and negotiate their roles within, the practice of convergent sports journalism and the ascension of new online journalism values in the Postmedia Network. We examine the institutionalization of 24/7 digital sports departments within which Postmedia’s sports journalists labour to produce a continuous flow of coverage of major league sport – at the expense of local amateur events and women’s sport – to secure a digital audience commodity of male readers. We also explore Postmedia’s embracement of outsourced labour and production processes that have further altered the work routines of sports journalists and have undermined quality standards. Finally, we underscore how the expansion of the digital promotional networks of major league sport has contributed to the ongoing historical erosion of the status and influence of sports journalists in the sports–media complex and has spurred the rise of derivative analytical and opinion-driven content.