bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPROVING THE COMPETITIVENESS OF FRIED ONION PRODUCTS THROUGH DISSEMINATION OF PRODUCTION TECHNOLOGY IN FRIED ONION SMES, NGANJUK REGENCY
Authors:   Faculty of Agricultural Technology, Universitas Brawijaya, Jl. Veteran, Faculty of Agricultural Technology  Universitas Brawijaya, Malang 65145, Indonesia, Pranowo Dodyk
Published: February 2023

The existence of fried onion processing SMEs has a very important role in the community's economy, this is because of the integration of the upstream and downstream sectors. Fried onion SMEs in Nganjuk Regency have two basic problems, namely limited production capacity and inconsistent quality of fried onions produced. The limited production capacity of fried onion SMEs is due to the fact that SMEs do not yet have adequate frying equipment and the quality inconsistency of fried onions is caused by an imperfect drying process. The purpose of this study is to analyze the internal and external conditions of Fried Onion SMEs in Nganjuk Regency. The method used in this research is SWOT analysis. Fried onion SMEs in Nganjuk Regency with their fried onion products have strengths including Strategic Business Locations, Regional Food Products, Product Prices According to Market, and Affordable Prices. This Fried Onion UKM has the opportunity to increase its competitiveness by optimizing opportunities such as Production Capacity Capable of Meeting the Market, Sufficient Manpower Available, Public Purchasing Power for Relatively High Products, Aid Programs from the Government, and Training Provided by the Local Government in collaboration. Meanwhile, the threats from SMEs are Fluctuating Raw Material Prices, Quite A Number of Competitors for Similar Products, and Differences in Pricing with Competitors.
Strengthening The Marketing Network Of Sumberwangi Village Batik Derivative Products Through Online Marketing And Expo
Authors:   Universitas Brawijaya, Malang, Indonesia, Surya Wardhani Ni Wayan , Setiawan Romi , Bintarto Redi , Shanti Manipuspika Yana , Ariyanto Danang , Cahya Cahya Rini Dian
Published: February 2023

Program doktor mengabdi dilaksanakan di Dusun Sumberwangi, Kecamatan Karangploso, Kabupaten Malang. Tujuan dari kegiatan doktor mengabdi ini adalah untuk mengembangkan dan memperkuat jejaring pemasaran produk turunan batik melalui pemasaran online dan kegiatan expo. Kelompok batik Dusun Sumberwangi memiliki permasalahan yaitu permintaan produk turunan batik yang masih stagnan dan belum adanya penerapan pemasaran produk. Berdasarkan hasil diskusi antara tim doktor mengabdi dapat diindikasikan bahwa kelompok batik belum memaksimalkan kegiatan promosi untuk memasarkan produk turunan batik. Metode yang dilakukan untuk mengatasi permasalahan kelompok batik Dusun Sumberwangi yaitu dilakukan pendampingan untuk kegiatan promosi dan mendaftarkan serta memasarkan produk-produk turunan batik melalui media online serta mengikuti kegiatan expo. Luaran dari kegiatan ini adalah produk turunan batik Dusun Sumberwangi semakin dikenal oleh masyarakat umum, kelompok batik Sumberwangi mampu mengelola berbagai metode promosi berbasis online dan mampu memanfaatkannya untuk peningkatan penjualan dan produksi produk turunan batik.
Josef Früchtl: Demokratie der Gefühle
Authors: Schindel Andreas
Published: February 2023

Rezension von Josef Früchtl: Demokratie der Gefühle. Ein ästhetisches Plädoyer. Hamburg: Meiner 2021.
Patients’ Experiences of a National Patient Portal and Its Usability: Cross-Sectional Survey Study (Preprint)
Authors: Simola Saija , Hörhammer Iiris , Xu Yuhui , Bärkås Annika , Fagerlund Asbjørn Johansen , Hagström Josefin , Holmroos Mari , Hägglund Maria , Johansen Monika Alise , Kane Bridget , Kharko Anna , Scandurra Isabella , Kujala Sari
Published: February 2023

BACKGROUND

Patient portals not only provide patients with access to electronic health records (EHRs) and other digital health services, such as prescription renewals, but they can also improve patients’ self-management, engagement with health care professionals (HCPs), and care processes. However, these benefits depend on patients’ willingness to use patient portals and, ultimately, their experiences with the usefulness and ease of use of the portals.

OBJECTIVE

This study aimed to investigate the perceived usability of a national patient portal and the relationship of patients’ very positive and very negative experiences with perceived usability. The study was aimed to be the first step in developing an approach for benchmarking the usability of patient portals in different countries.

METHODS

Data were collected through a web-based survey of the My Kanta patient portal’s logged-in patient users in Finland from January 24, 2022, to February 14, 2022. Respondents were asked to rate the usability of the patient portal, and the ratings were used to calculate approximations of the System Usability Scale (SUS) score. Open-ended questions asked the patients about their positive and negative experiences with the patient portal. The statistical analysis included multivariate regression, and the experience narratives were analyzed using inductive content analysis.

RESULTS

Of the 1,262,708 logged-in patient users, 4719 responded to the survey, giving a response rate of 0.37%. The patient portal’s usability was rated as good, with a mean SUS score of 74.3 (SD 14.0). Reporting a very positive experience with the portal was positively associated with perceived usability (β=.51; P<.001), whereas reporting a very negative experience was negatively associated with perceived usability (β=−1.28; P<.001). These variables explained 23% of the variation in perceived usability. The information provided and a lack of information were the most common positive and negative experiences. Furthermore, specific functionalities, such as prescription renewal and the ease of using the patient portal, were often mentioned as very positive experiences. The patients also mentioned negative emotions, such as anger and frustration, as part of their very negative experiences.

CONCLUSIONS

The study offers empirical evidence about the significant role of individual experiences when patients are evaluating the usability of patient portals. The results suggest that positive and negative experiences provide relevant information that can be used for improving the patient portal’s usability. Usability should be improved so that patients receive information efficiently, easily, and quickly. Respondents would also appreciate interactive features in the patient portal.
Consensus Guidelines for Teledermatology: Scoping Review (Preprint)
Authors: Cummins Mollie R , Ong Triton , Ivanova Julia , Barrera Janelle F , Wilczewski Hattie , Soni Hiral , Welch Brandon M , Bunnell Brian E
Published: February 2023

BACKGROUND

Consensus guidelines and recommendations play an important role in fostering quality, safety, and best practices, as they represent an expert interpretation of the biomedical literature and its application to practice. However, it is unclear whether the recent collective experience of implementing telemedicine and the concurrent growth in the evidence base for teledermatology have resulted in more robust guidance.

OBJECTIVE

The objective of this review was to describe the extent and nature of currently available guidance, defined as consensus guidelines and recommendations available for telemedicine in dermatology, with guidance defined as consensus or evidence-based guidelines, protocols, or recommendations.

METHODS

We conducted a single-reviewer scoping review of the literature to assess the extent and nature of available guidance, consensus guidelines, or recommendations related to teledermatology. We limited the review to published material in English since 2013, reflecting approximately the past 10 years. We conducted the review in November and December of the year 2022.

RESULTS

We identified 839 potentially eligible publications, with 9 additional records identified through organizational websites. A total of 15 publications met the inclusion and exclusion criteria. The guidelines focused on varied topics and populations about dermatology and skin diseases. However, the most frequent focus was general dermatology (8/15, 53%). Approximately half of the telemedicine guidance described in the publications was specific to dermatology practice in the context of the COVID-19 pandemic. The publications were largely published in or after the year 2020 (13/15, 87%). Geographical origin spanned several different nations, including Australia, the United States, European countries, and India.

CONCLUSIONS

We found an increase in COVID-19–specific teledermatology guidance during 2020, in addition to general teledermatology guidance during the period of the study. Primary sources of general teledermatology guidance reported in the biomedical literature are the University of Queensland’s Centre for Online Health and Australasian College of Dermatologists E-Health Committee, and the American Telemedicine Association. There is strong evidence of international engagement and interest. Despite the recent increase in research reports related to telemedicine, there is a relative lack of new guidance based on COVID-19 lessons and innovations. There is a need to review recent evidence and update existing recommendations. Additionally, there is a need for guidance that addresses emerging technologies.
Prevalence and Risk Factors of Stroke in Rural Bangladesh: A Survey with Community Health Workers on 1·3 million people (Preprint)
Authors: Sarker Farhana , Ripan Rony Chowdhury , Chowdhury Moinul H. , Islam AKM Nazmul , Rahman Md. Mashiar , Islam Shariful , Saha Shumit , Mamun Khondaker A.
Published: February 2023

UNSTRUCTURED

Stroke is a leading cause of death and long-term disability worldwide, with an estimated 6.2 million deaths each year. In Bangladesh, data on stroke prevalence and risk factors in rural areas is limited, making it difficult to develop effective early prevention and intervention programs. This study aimed to present the prevalence of stroke in a rural community in Bangladesh and to identify and associate various stroke risk factors.
Data collection was done by community health workers (CHWs), as a part of “Enriched Sastho” program of Palli Karma Sahayak Foundation, Bangladesh. CHWs received two weeks of training to ensure data quality. The presence of stroke was determined by a binary survey question, with a history of stroke indicated by a "1" and absence indicated by a "0".
The study analyzed data from 1,341,589 individuals, with an average age of 29.23 years. The overall stroke prevalence was found to be 1.07 per 1,000 people, with higher prevalence in males and increases with age. The highest stroke prevalence was observed in the Khulna division and the least in the Rangpur division. Hypertension (67.55%) and diabetes (25.21%) were the most common non-communicable diseases among stroke patients.
The study emphasizes the need for early prevention and intervention programs for stroke in rural Bangladesh and the importance of managing hypertension and diabetes to reduce stroke risk.
Drug-Resistant Tuberculosis Case-Finding Strategies: Scoping Review (Preprint)
Authors: van Wyk Susanna S , Nliwasa Marriott , Lu Fang-Wen , Lan Chih-Chan , Seddon James A , Hoddinott Graeme , Viljoen Lario , Günther Gunar , Ruswa Nunurai , Shah N Sarita , Claassens Mareli
Published: February 2023

BACKGROUND

Finding individuals with drug-resistant tuberculosis (DR-TB) is important to control the pandemic and improve patient clinical outcomes. To our knowledge, systematic reviews assessing the effectiveness, cost-effectiveness, acceptability, and feasibility of different DR-TB case-finding strategies to inform research, policy, and practice, have not been conducted and the scope of primary research is unknown.

OBJECTIVE

We therefore assessed the available literature on DR-TB case-finding strategies.

METHODS

We looked at systematic reviews, trials, qualitative studies, diagnostic test accuracy studies, and other primary research that sought to improve DR-TB case detection specifically. We excluded studies that included patients seeking care for tuberculosis (TB) symptoms, patients already diagnosed with TB, or were laboratory-based. We searched the academic databases of MEDLINE, Embase, The Cochrane Library, Africa-Wide Information, CINAHL (Cumulated Index to Nursing and Allied Health Literature), Epistemonikos, and PROSPERO (The International Prospective Register of Systematic Reviews) using no language or date restrictions. We screened titles, abstracts, and full-text articles in duplicate. Data extraction and analyses were carried out in Excel (Microsoft Corp).

RESULTS

We screened 3646 titles and abstracts and 236 full-text articles. We identified 6 systematic reviews and 61 primary studies. Five reviews described the yield of contact investigation and focused on household contacts, airline contacts, comparison between drug-susceptible tuberculosis and DR-TB contacts, and concordance of DR-TB profiles between index cases and contacts. One review compared universal versus selective drug resistance testing. Primary studies described (1) 34 contact investigations, (2) 17 outbreak investigations, (3) 3 airline contact investigations, (4) 5 epidemiological analyses, (5) 1 public-private partnership program, and (6) an e-registry program. Primary studies were all descriptive and included cross-sectional and retrospective reviews of program data. No trials were identified. Data extraction from contact investigations was difficult due to incomplete reporting of relevant information.

CONCLUSIONS

Existing descriptive reviews can be updated, but there is a dearth of knowledge on the effectiveness, cost-effectiveness, acceptability, and feasibility of DR-TB case-finding strategies to inform policy and practice. There is also a need for standardization of terminology, design, and reporting of DR-TB case-finding studies.

CLINICALTRIAL
Conservative treatment of patients with secondary adhesive capsulitis
Authors: Strafun S.S. , Bohdan S.V. , Yuriychuk L.М. , Strafun O.S.
Published: February 2023

Background. Secondary adhesive capsulitis, similar to idiopathic one, is accompanied by thickening of the glenohumeral joint capsule and loss of its elasticity. Nonoperative management of secondary adhesive capsulitis associated with shoulder soft tissue injuries, impact of prolonged immobilization or surgical treatment still remains controversial. Capsular distension with steroids as in idiopathic adhesive capsulitis is often not used for one reason or another. The purpose: to compare the results of conservative treatment in patients with secondary adhesive capsulitis who underwent or not capsular distension with steroids during the treatment. Materials and methods. From 2015 to 2021 at the Department for Microsurgery and Reconstructive-Recovery Surgery of Upper Limb of the State Institution “Institute of Traumatology and Orthopaedics of the National Academy of Medical Sciences of Ukraine” (Kyiv) and Ivano-Frankivsk Regional Clinical Hospital, we have conducted conservative treatment for 825 patients with various soft tissue pathology of the shoulder joint complicated by secondary adhesive capsulitis. All patients were divided into two groups: first one— conservative treatment, second one — conservative treatment with intraarticular injections (capsular distension) with steroids. In our study, we evaluated the function of the shoulder joint using the Constant Shoulder Score (CSS) and visual analog scale (VAS) before treatment and after 3 and 6 months. Results. Patients from first group (conservative treatment without distension intraarticular injections) had worse average functional results 3 month after starting treatment according to CSS (p=0.13) and VAS (p=0.24) compared to subjects of second group. Six months after the start of treatment, patients from first group had significantly worse results by CSS and VAS than those from group 2, where distension intraarticular injections were performed (p=0.03 and p = 0.06, respectively). Conclusions. Conservative treatment of patients with secondary adhesive capsulitis of the shoulder joint should be comprehensive, differentiated and include both non-drug treatment methods and distension intraarticular injections with long-acting steroids.
Sarcopenia and rheumatic diseases: is there any connection?
Authors: Dzhus M.B. , Kulyk M.S. , Karasevska T.A. , Mostbauer H.V. , Ivashkivskyi O.I. , Potomka R.A. , Novytska H.L.
Published: February 2023

Sarcopenia is characterized by a loss of skeletal muscle mass, a decrease in muscle strength and/or physical performance, and is one of the main causes for limiting daily activities in the elderly. This is associated with an increased incidence of many adverse events such as dysfunction, falls, frailty, hospitalization, disability, and mortality. Primary (considered as a part of the aging process) and secondary sarcopenia (due to malabsorption, immobility/bed rest, starvation, hypothyroidism, osteoporosis, immune-mediated rheumatic diseases) are united by a chronic inflammatory process of different degrees. Sarcopenia supports one of the most widely accepted theories that low-grade chronic inflammation is important in the pathogenesis of many diseases. For a long time, sarcopenia was considered an age-related disease, but recently it has been reported to be more common in young subjects with autoimmune diseases. In particular, the relationship between sarcopenia and rheumatic diseases such as rheumatoid arthritis has been studied in detail. Although the pathogenesis of sarcopenia in autoimmune diseases is not fully understood, it is believed that a chronic inflammatory process contributes to the development of loss of muscle mass and strength, and is different depending on the underlying disease. The definition of sarcopenia varies between studies, which complicates and limits direct comparisons. Therefore, in this review, we demonstrate various diagnostic criteria for sarcopenia, focusing on its prevalence in patients with rheumatic diseases, including rheumatoid arthritis, juvenile idiopathic arthritis, axial spondylitis, psoriatic arthritis, and systemic sclerosis. We developed a structured search strategy for English language publications in PubMed using the term “sarcopenia” in combination with the following keywords: “inflammation”, “diagnosis”, “criteria”, “muscle mass”, “strength”, “outcomes”, “disability”, “mortality”, “pathophysiology”, “rheumatoid arthritis”, “juvenile arthritis”, “axial spondylitis”, “psoriatic arthritis”, “systemic sclerosis”. We focused on clinical trials, meta-analyses and review articles. Articles published only after 2000 year were included, however, we did not include major contributions published before. The search was completed on October 8, 2022.
Analysis and Design of Highrise Building G+12 With Swimming Pool at Top and Shaer Wall by Using Staad-Pro with Seismic Loading in All Zones
Authors: Koul Sheetal , Lalotra Sourabh
Published: February 2023

Abstract: In these modern days the Buildings are made to fulfill our basic aspects and better Serviceability. The aim of the Structural engineers are to design the structures safe, durable and economical. It is not an issue to construct a Building any how its, important to construct an efficient building which will serve for many years without showing any failure. Unique structures need more time for its time consuming calculations, if we use manual methods. STAAD Pro provides us a quick results. It is easy to use for analyze and design any structure for more accuracy. In the STAAD Pro limit state method is use as per Indian Standard Code and Practices. We can conclude that this software can save much time and very accurate in designs. The Project aims in finding better technique for creating Geometry, defining the cross sections for column and beam etc., Creating supports (to define a support weather it is fixed or pinned),then the Loads are defined (mainly under seismic and wind loads). After that the model is analyzed by ‘run analysis’. Then reviewing (whether beam column passed in loads or failed) results. Then the design performed. After all analysis, We can say that there is a much variation in results as the positon of swimming pool plays an important role in the designing of the building and here it’s been concluded that the single side positon pool comprises the best position for the regular buildings and the kind I shear wall suggested within this analysis turns out to be more effective and can achieve maximum safety towards earthquake.
Strength Characteristics of Hybrid Fiber Reinforced Concrete Produced with Different Aspect Ratios
Authors: M P Dr. Rudraswamy , Patagundi Dr. B. R
Published: February 2023

Abstract: Nowadays, fibre reinforced concrete is more popular due to its improved ductility properties. It can be transformed into a useful construction material in areas where earthquake pressures are likely to cause harm. The ability of the materials to absorb energy in these situations is crucial. The addition of various fibres, such as carbon, steel, polypropylene, or any other type of fibre, will increase the concrete's ability to absorb energy. There isn't enough research on the effects of using hybrid fibres with various aspect ratios to concrete. This experimental study sheds some information on how hybrid fibre reinforced concrete behaves when fibres of different aspect ratio are used. Strength characteristics like compressive strength, tensile strength, flexural strength, shear strength, and impact strength are determined for concrete produced by using fibers of different aspect ratios
A Study on the Establishment of a Commercialization Model for the Activation of AI Smart Housing Service and Platform
Authors:   Residential Environment Institute Of Korea, Cho Yong kyung , Kim Jae hwan
Published: February 2023

In Korea, the demand for new housing services is increasing due to changes in the demographic structure, but in terms of activation, affordable and universal housing services are lacking. Therefore, in this study, the necessity of revitalizing the AI smart housing market was confirmed in terms of housing service activation, and through AI smart market analysis, various market participants tried to analyze the market access patterns in two factors: price and function. In addition, it was intended to present a commercialization model including price, target market, and service provided for the activation of AI smart housing.
As a result of the study, although there is a difference in the level of functions, various industries in the front and rear are forming the market in terms of the implementation of AI smart housing. As a result of quantifying the functions of 16 similar/competitive markets and alternative markets based on a total of 11 functional levels, it was found that the lowest two functional levels had a maximum functional level of 7.5. In the case of AI smart housing service and platform, it was analyzed that a functional level of about 6.5-8 would be implemented. In the case of the price range, it was found that the distribution method of subscription was determined in the range of 0.11 to 6.49 million won/month. In the case of distribution by purchase, simple products start at about 20 million won, but when implemented with smart home appliances, the price is formed up to about 20 million won.
Finally, seven types of commercialization models were established by comprehensively summarizing the target market and characteristics of the target market, price level, platform function, and core customer value (service). It was classified into entry-level, entry-level youth, entry-level elderly, high-end type, 1-2-person household type, high-end type, 3-4-person household type or more, high-end senior type, and high-end type. In the case of the entry-level type, it can be considered for application in terms of housing welfare, which has recently been attracting attention.
Mapping of toronipa coastal tourism in konawe regency south east sulawesi province
Authors: Puguh Lolita Saraswati , Koerniawaty Francisca Titing , Mahendra I Wayan Eka
Published: February 2023

This research provides substantial data to reinvigorate Toronipa marine tourism in Konawe Regency, Southeast Sulawesi Province, then this research aims to map the potential attractions around Toronipa beach, and deeply analyze the challenges faced in order to revitalize Toronipa coastal tourism, so that an appropriate development model can be designed for Toronipa coastal tourism destinations. This research implements the initial stage of the Research & Development approach, is a need analysis stage by mapping the potential and challenges with qualitative analysis methods. Data were collected using passive participatory observation techniques, interviews and FGDs. The results showed that the main potential attraction is a beautiful white sandy beach along the 4 km coastline. There are typical Toronipa culinary, tourist facilities in the form of gazebos, toilets, rides and water attractions. The accessibility to destinations is in good condition. The existence of tourism awareness group, tourism human resources and friendly people in welcoming tourists. The challenges faced in developing Toronipa coastal tourism are the unavailability of adequate marine vehicle facilities, the number of artificial attractions is not much, some tourist facilities such as gazebos and toilets are not well maintained, parking lots are still inadequate, and there is no marine tour guide service.
Variación latitudinal del tamaño corporal de Tegula atra (Lesson, 1830) (Gasterópodo: Trochidae) en aguas someras del sur de Chile
Authors: Palacios Subiabre Mauricio , Aldea Cristian , Corcoran Derek
Published: February 2023

La gran variabilidad de los ambientes marinos en Chile está asociada a la longitud de su costa, la cual está regulada por diversos procesos oceanográficos que perfilan la distribución, abundancia y morfología de las especies marinas. Tegula atra es un gasterópodo marino de gran distribución en el Pacífico sur, cualidad que le permite ser un buen modelo de estudio para evaluar la variación de su tamaño corporal respecto a su distribución latitudinal. Un total de 236 individuos fueron recolectados en siete sitios de muestreo entre 41,6 ° ~ 53,6 °S. La relación entre el peso, la talla (media geométrica) y su distribución latitudinal fue evaluada de acuerdo con regresiones de Pearson y de cuantiles. En relación con la latitud, se observó una correlación positiva y sustancial (Pearson) entre el peso y la talla (p > 0,05) al desplazarse hacia el sur. Los resultados de la regresión de cuantiles reflejaron que tanto la pendiente como el valor R2 son significativos para la latitud con las dos variables analizadas (peso, media geométrica). Entre los factores que afectan al tamaño corporal de T. atra, se sugiere una diferenciación adaptativa de este género a diferentes temperaturas -lo que ya se ha observado en especies antárticas-. Esto revela una interacción entre la latitud, la fertilidad y el suministro de alimento, condición que se refleja en T. atra en la ecorregión subantártica. Sin embargo, el estudio de las zonas intermedias en el sur de Chile y la interacción con otros factores abióticos (por ejemplo, la profundidad) puede dilucidar estas variaciones en el tamaño corporal.
Nuevos antecedentes de mamíferos nativos y exóticos de hábitos semiacuáticos en el islote Albatros, Seno Almirantazgo
Authors: Dougnac Catherine , Arredondo Cristobal , Constanzo Javiera , Kusch Alejandro , Vila Alejandro
Published: February 2023

Entre las especies de mamíferos con hábitos semiacuáticos presentes en Chile se encuentran dos mustélidos nativos, el chungungo (Lontra felina) y el huillín (Lontra provocax). Asimismo, han sido introducidos dos mamíferos semiacuáticos exóticos e invasores en el país, el visón americano (Neovison vison) y el castor americano (Castor canadensis). Estas últimas especies son ampliamente reconocidas por los efectos negativos que provocan sobre los ecosistemas y las especies nativas. Si bien todas estas especies incluyen en su distribución más austral al archipiélago de Tierra del Fuego, en la región de Magallanes, existen pocos antecedentes documentados sistemáticamente sobre su presencia en canales interiores. En este estudio se describe la presencia de mamíferos semiacuáticos mediante el monitoreo con cámaras trampa en el Islote Albatros, en el Seno Almirantazgo entre las temporadas estivales 2016 – 2017 y 2021 – 2022, con esfuerzos de muestreo (EM) que variaron entre 499 durante la temporada 2018-2019 y 3.658 en 2020-2021. A partir de los registros obtenidos se calcularon los índices de abundancia relativa (IAR) para cada una de las especies registradas: visón americano (rango=0-8), huillín (rango=0,08 – 5) y castor americano (rango=0-0,144). Se destaca el primer registro de presencia de castor y huillín para el Islote Albatros, confirmándose además la reproducción de esta última especie en este. Estos hallazgos resultan de gran relevancia en el contexto de los objetos de conservación del Área Marina Costera Protegida de Múltiples Usos (AMCP-MU) Seno Almirantazgo, pues son un aporte clave para la toma de decisiones informada y el manejo efectivo de esta área protegida. También resaltan la importancia de implementar y sostener esfuerzos de monitoreo sistemáticos tanto de los objetos de conservación del área como de las amenazas que enfrentan.
Boundary singular problems for quasilinear equations involving mixed reaction-diffusion
Authors: Véron L.
Published: February 2023

We study the existence of solutions to the problem

\[\label{eng_A1}

\begin{array}{rl}

-\Delta u+u^p-M|\nabla u|^q=0 \text{in }\;\Omega,\\

u=\mu \text{on }\;\partial\Omega

\end{array}\]

in a bounded domain \(\Omega\), where \(p1\), \(1q2\), \(M0\), \(\mu\) is a nonnegative Radon measure in \(\partial\Omega\), and the associated problem with a boundary isolated singularity at \(a\in\partial\Omega,\)

\[\label{eng_A2}

\begin{array}{rl}

-\Delta u+u^p-M|\nabla u|^q=0 \text{in }\;\Omega,\\

u=0 \text{on }\;\partial\Omega\setminus\{a\}.

\end{array}\]

The difficulty lies in the opposition between the two nonlinear terms which are not on the same nature. Existence of solutions to[eng_A1] is obtained under a capacitary condition \[\mu(K)\leq

c\min\left\{cap^{\partial\Omega}_{\frac{2}{p},p'},cap^{\partial\Omega}_{\frac{2-q}{q},q'}\right\}\quad\text{for

all compacts }K\subset\partial\Omega.\] Problem[eng_A2] depends on several critical exponents on \(p\) and \(q\) as well as the position of \(q\) with respect to \(\dfrac{2p}{p+1}\).
On a system of differential equations with random parameters
Authors: Zadorozhniy V. G. , Tikhomirov G. S.
Published: February 2023

An explicit formula for the mathematical expectation and second moment functions of a solution to a linear system of ordinary differential equations with a random parameter and a vector random righthand side is obtained. The problem is reduced to the deterministic Cauchy problem for systems of first-order linear partial differential equations. We obtain an explicit formula for a solution of linear systems of partial differential equations of the first order with constant coeffcients. An example is given showing that random factors can have a stabilizing effect on a linear system of differential equations.
A model of string system deformations on a star graph with nonlinear condition at the node
Authors: Zvereva M. B.
Published: February 2023

In this paper, a model of deformations of Stieltjes strings system located along a geometric star graph with a nonlinear condition at the node is studied. This kind of condition arises due to the presence of a limiter for the movement of strings in the node under the in uence of an external load. In the present paper, the necessary and sufficient conditions for the extremum of the energy functional are established; existence and uniqueness theorems for the solution are proved; the critical loads at which the strings come into contact with the limiter are analyzed; the dependence of the solution on the limiter length is studied.
Mafhum Al Naskh min Mandhur Al Fiqh Al Maqashidiy: Dirasat wa Niqasy
Authors: Mubarrak Husni , Munir Badrul
Published: February 2023

This simple article discusses the concept of naskh and its division in Qur'anic studies. The study of naskh has become increasingly important, not only in ulumul Qur'an but also extending to other Shari'ah disciplines, including the science of ushul fiqh, which concentrates on the discovery of legal arguments and methods of istinbath Shari'ah law. This article argues for the importance of reviewing the study of naskh by placing maqashid scales as a parameter on the fulfillment of benefits and harms, especially with regard to the classification of naskh and the distribution of examples. The author uses the literature study method in this research by referring to motherbooks in classical ulumul Qur'an studies as well as various contemporary references, including recent scientific journal articles, in order to discuss the issue of the concept of naskh in the review of fiqh maqashid studies and debate the long-circulating shubhat views surrounding the study of naskh. The results of the study show that the division of the kinds of naskh by rasm and tilawah as narrated in 'ulumul Qur'an into three forms - according to the review of Fiqh Maqashid - is unacceptable, because it opens the door to doubt and even skepticism about the Book of Allah, therefore such a model of naskh division must be rejected to realize a greater and greater benefit in maintaining this religion and maintaining the sanctity and authenticity of the Qur'an.يهتم هذا البحث المتواضع بموضوع النسخ ونقاش مفهومه في دراسة علوم القرآن من منظور الفقه المقاصدي. تصبح دراسة النسخ ذات أهمية قصوى ليست فقط في علوم القرآن بمعرفة المقدم والمؤخر من آيات القرآن المنزلة، بل تتوسع إلى العلوم الشرعية، من بينها علم أصول الفقه الذي يعتني بالعثور على الأدلة وطريقة استنباط الأحكام الشرعية. يطرح هذا المقال إعادة النظر في دراسة مفهوم النسخ بوضع الاعتبار المقاصدي من حيث المصلحة والمفسدة، خاصة فيما يتعلق بتقسيمات النسخ وأمثلتها. يستخدم الباحث طريقة دراسات مكتبية في هذا المقال سواء أكانت من كتب التراث أو الكتب المعاصرة، من بينها النشرات العلمية، للنقاش عن هذا الموضوع من منظور الفقه المقاصدي وطرد الآراء المشبوهة حول دراسة النسخ. وتدل نتيجة البحث على أن تقسيمات النسخ كما هو مروي ومدعى في علوم القرآن حسب منظور الفقه المقاصدي لا يصح معناه أبدا، بل يفتح بابا للتشكيك في كتاب الله تعالى، ولذا لا يجوز قبوله لأجل المصلحة العظمى في حفظ الدين وحماية القرآن.
Persuasive Missionary Endeavor in The Story of Prophet Musa and Fir’aun: Study of Chapter Thaha Verse 44
Authors: Fauziah Mira
Published: February 2023

Persuasive da'wah is a da'wah that is carried out in a gentle and warm way. Not all da'i can apply persuasive da'wah to their mad'unya. Some da'i still exist who preach using language that does not touch the heart. This paper aims to find out how persuasive preaching was carried out by the prophets Moses and Aaron against Fir'aun. This paper uses the countenance analysis method, which analyzes the meaning of Surah Thaha, verse 44, of the Qur'an using the theory of persuasive da'wah. The results showed that the Al-Quran Surah Thaha, verse 44, reveals the story of Prophet Moses and Prophet Aaron preaching to Pharaoh in a gentle way even though Pharaoh knew that he was a despotic king and disobeyed Allah. The term "qaulan layyina" has a meaning that is gentle, pleasant to hear, touches the heart, and reassures the mind. Prophet Moses and Prophet Aaron have done persuasive da'wah with several methods, namely: the association method, integration, payoff, fear-arousing, and icing methods. This was done in the hope that Pharaoh would be touched by his heart and fear Allah so that he would believe in
Peran Pengambil Kebijakan dan Masyarakat dalam Pencegahan Penularan Filariasis (Studi Kualitatif)
Authors: Santoso Santoso , Yahya Yahya , Taviv Yulian , Rahayu Katarina Sri , Supranelfi Yanelza , Mahdalena Vivin , Nurmaliani Rizki , Arisanti Maya , Marini Marini , Suryaningtyas Nungki Hapsari , Surya Permadi I Gede Wempi Dody , Wurisastuti Tri
Published: February 2023

Filariasis is still a health problem in East TanjungJabung and Belitung regencies even though mass treatment activities have been carried out for five rounds. Both districts are still endemic for filariasis because the Microfilaria rate (Mf rate) is still more than 1%. This study aims to identify the role of the community of various parties in controlling filariasisin Tanjung Jabung Timur and Belitung regencies. The research design is descriptive with a qualitative approach. Informants for the in-depth interviews were health workers at the district, sub-district and village levels as well as the village community. The number of health worker informants was 10 people, 16 community leaders, 16 cadres, and 9 sufferers, while the FGD consisted of 4 groups. Each group consists of 7 participants. Data was collected through in-depth interviews and group discussions and the data were analyzed qualitatively. Recruitment of informants for determining in-depth interviews using the snow ball method. The results showed that the roles of officers and policy makers in TanjungJabung Timur Regency were quite good, but in Belitung Regency they were less involved. Meanwhile, the role of community leaders in Indonesia is still not optimal in controlling filariasisespecially in disseminating information about filariasis. Therole of community leaders in East Tanjung Jabung Regency is more powerful than Belitung Regency. Filariasis control activities still need support from policy makers in allocating budgets and the role of community leaders to mobilize the community to be actively involved in controlling filariasis.
O uso de plantas medicinais e medicamentos por idosos: uma revisão integrativa
Authors: Ribeiro de Souza Samara , Silva Portella Yhasmyn , Rodrigues de Oliveira Rebeca , Santos Souza Suelen , Lima Carneiro Isadora
Published: February 2023

Plantas medicinais são usadas para diversas finalidades, como calmante, cicatrizante, ação anti-inflamatória, digestivas, dentre outras funções, porém seu uso excessivo ou sem acompanhamento de um profissional qualificado pode se transformar em uma sucessão de riscos. Esses impactos a saúde podem acometer mais os idosos, pois estes sentem-se mais confortáveis fazendo tratamento com plantas medicinais do que medicamentos produzidos pelas indústrias farmacêuticas. Vários problemas como interação na absorção do medicamento, potencialização ou até inibição podem ser provocados pelas mesmas. Esta revisão integrativa contém uma abordagem qualitativa que tem como objetivo principal identificar os riscos associados as interações farmacológicas entre plantas medicinais e medicamentos utilizados pelos idosos. A partir dos critérios de inclusão e exclusão foram selecionados 10 estudos, a planta mais citada foi a camomila (Matricaria chamomilla L) presente em 19,4%, e foi identificado trinta e um fármacos diferentes. Algumas das plantas que causam determinados riscos são citadas neste artigo, visando dessa forma alertar e conscientizar os leitores dos problemas gerados para a terceira idade. Concluindo que é necessário implementar medidas educacionais, principalmente em asilos acerca do uso de plantas medicinais concomitantemente a medicamentos.
Risk factors for allergy: Evidence from cross sectional analysis of a UK primary care database.
Authors: Diwakar Lavanya , Subramanian Anuradhaa , K Divya Shah , Subramaniam Sumithra , S Victoria Pelly , Greenfield Sheila , Moore David , Nirantharakumar Krishnarajah
Published: February 2023

Background: As the global prevalence of allergy increases, it is clear
that more individuals are presenting with complex and multiple
allergies. The impact of various demographic and clinical risk factors
on developing allergies has not been explored at a population level.
Objectives: To ascertain if age, gender, ethnicity, UK geographical
region of residence and being diagnosed with another allergy affect the
risk of having allergies. Methods: A retrospective analysis was
performed using cross-sectional data for the year 2018 extracted from
the from the health improvement network (THIN) database. THIN is a live
primary care database which holds entries about 6% of the UK
population. A logistic regression analysis was carried out using
demographic data and allergy diagnoses as independent variables.
Results: Of the 3.03 million records analysed, 49.8% were male and
19.7% were children (aged < 18 yrs). There were gender,
ethnicity and region-based differences in the prevalence of GP diagnosed
allergic diseases in the UK. The odds of developing anaphylaxis are
highest in individuals with food allergy [OR: 54.57 (95%CI:
45.65-65.22); p<0.001 for children and OR:18.05 (95%
CI:16.79-19.41); p<0.001 for adults respectively].
Individuals with any diagnosed allergy had significantly higher odds of
being diagnosed with others. Conclusions: Having an allergy
significantly increases the odds of being diagnosed with others. There
are age, gender, ethnicity and region based differences in the
prevalence of allergies. These data suggest that the number of
individuals with multiple allergies is increasing and that the needs of
increasingly cosmopolitan populations should be taken into account when
planning allergy services.
Smart Process Analytics for the End-to-End Batch Manufacturing of Monoclonal Antibodies
Authors: Braatz Richard , Hong Moo Sun , Mohr Fabian , Castro Chris D. , Smith Benjamin T. , Wolfrum Jacqueline , Springs Stacy , Sinskey Anthony , Hart Roger A. , Mistretta Tom
Published: February 2023

For many modern biopharmaceutical processes, manufacturers develop
data-driven models using data analytics/machine learning (DA/ML)
methods. The challenge is how to select the best methods for a specific
dataset to construct the most accurate and reliable model. This article
describes the application of smart process data analytics software to
industrial end-to-end biomanufacturing datasets for monoclonal antibody
production to automate the determination of the best DA/ML tools for
model construction and process understanding. The application
demonstrates that smart process data analytics software captures
product- and process-specific characteristics for two different
monoclonal antibody productions. This study provides tools that can be
widely applied to biomanufacturing processes for root cause analysis,
prediction, and control.
Head shape and bite loading demands in Pheidole ant workers
Authors: Klunk Cristian , Argenta Marco , Ferreira Alexandre Casadei , Pie Marcio
Published: February 2023

Workers in the ant genus Pheidole show an extreme degree of
morphological differentiation, with at least two distinct subcastes:
minor workers are smaller and perform most of the colony tasks, whereas
majors are larger, display disproportionately massive heads, and
specialize in roles as defense and food processing. There is
considerable interspecific variation in head shape within worker
subcastes of Pheidole, which could affect how the stresses
generated by the mandibular closing muscle contraction (0md1) spread
throughout the head and influence bite force. To assess the role of head
shape in stress patterns of Pheidole workers, we solve a set of
Finite Element Analysis (FEA) while exploring variation in
Pheidole worker head morphospace. We hypothesize that majors
possess head shapes optimized for the generation of stronger bites. In
addition, we expect that head shapes corresponding to the edges of
morphological space in the genus would show mechanical limitations that
could prevent further expanding the occupied morphospace. We vectorized
Pheidole head shapes based on images of worker heads, considering
species that represent mean shapes and the edges of the two main axes of
each morphospace, for a total of five head shapes for each worker
subcaste. We performed linear static FEA simulating the contraction of
0md1. Our results demonstrate that head shapes of majors are optimized
to generate stronger bites given that stress generated on those shapes
is distinctly directed towards the mandibles. Head shapes of minors
tended to concentrate stresses around the mandibular articulations, with
substantially lower and more diffuse stresses spreading throughout the
head, indicating that such shapes are associated with weaker bites. Our
results agree with the expectations regarding the main colony tasks
performed by each worker subcaste, and we find some evidence of
biomechanical limitations on extreme head shapes for majors and minors.
Biodiversity protection against anthropogenic climate change: conservation prioritisation of Castanea sativa in the South Caucasus based on genetic and ecological metrics
Authors: Beridze Berika , Sękiewicz Katarzyna , Walas Łukasz , Thomas Peter, A. , Danelia Irina , Farzaliyev Vahid , Kvartskhava Giorgi , Sós Jan , Dering Monika
Published: February 2023

The climate drives species distribution and genetic diversity; the
latter defines the adaptability of populations and species. The ongoing
climate crisis induces tree decline in many regions, compromising the
mitigation potential of forests. Scientific-based strategies for
prioritising forest tree populations are critical to managing the impact
of climate change. Identifying future climate refugia, which are
locations naturally buffering the negative impact of climate change, may
facilitate local conservation. In this work, we conducted the
populations’ prioritisation for Castanea sativa (sweet chestnut), a
Neogene relict growing in the Caucasus global biodiversity hotspot. We
generated genetic and ecological metrics for 21 sites in Georgia and
Azerbaijan, which cover the natural range of sweet chestnut across the
region. We demonstrated that climate primarily drives the pattern of
genetic diversity in C. sativa, proved with a significant
Isolation-by-Environment model. In future, climate change may
significantly reorganise the species genetic diversity, inducing even
some genetic loss, especially in the very distinct eastern fringe of the
species range in Azerbaijan. Based on our combined approach, we mapped
populations suitable for ex-situ and in-situ conservation, accounting
for genetic variability and the location of future climate refugia.
A Review on Forensic DNA Analysis
Authors: Wang Mary
Published: February 2023

Forensic science is all about seeking the truth and justice through a
weaved web of minor details. In the status quo, forensic science is
almost completely dependent on the microscopic but unique molecules,
DNA. Forensic DNA analysis is the key element to the current convictions
and exonerations of suspects and identifying victims, accidents and
crimes, through collecting evidence and going through presumptive tests,
DNA analysis, profiling and going through the justice system.
Numerical Solution of Burgers' Equation Using Discrete Symmetries
Authors: Feroze Tooba , Rehman Haseeb Ur
Published: February 2023

Crank-Nicolson method is a finite difference scheme used to solve the
heat and other parabolic partial differential equations. In order to
solve the Burgers’ equation which is parabolic partial differential
equations, an invariant numerical scheme, based on Crank-Nicolson method
and discrete symmetries of Burgers’ equation, is established here. A
comparison of the proposed numerical scheme with the Crank-Nicolson
method and the exact solution is also presented. It is clearly observed
that the convergence and performance of the modified
Crank-Nicolson is better than that of the Crank-Nicolson method.