bluuebunny/crossref_metadata_2025 huggingface dataset:
Photo-catalytic Study of Malachite Green Dye Degradation Using Rice Straw Extracted Activated Carbon Supported ZnO Nano-particles
Authors: El-Salamony Radwa A. , Emam Abeer A. , Badawy Nagwa A. , El-Morsi Sara F.
Published: September 2019

Objective:

ZnO nanoparticles were synthesized using wet impregnation method, and
activated carbon from rice straw (RS) prepared through chemical route.

Methods:

The nano-composites ZnO-AC series were prepared with different ZnO:AC ratio of 10,
20, 50, and 70% to optimize the zinc oxide nanoparticles used. The obtained composites were
characterized by FE-SEM, XRD, SBET, and optical techniques then used for the photo-degradation
of Malachite green dye (MG) under visible light.

Results:

It was found that 10ZnO-AC exhibited excellent visible light photo-catalytic performance.
The ·OH radicals’ formation is matching with photo-activity of the prepared composites.
The photo-degradation efficiency of MG increased from 63% to 93%, when the 10ZnO-AC photocatalyst
amount was increased from 0.5 to 6 g/L.

Conclusion:

The GC-MS technique was used to analyze the intermediates formed; up to 15 kinds
of chemicals were identified as the degradation products.
Green Synthesis of Metal Nanoparticles from Adiantum Frond: Comparative Analysis on Cancer Cell Lines
Authors: Zamani Sabiha , Idrees Danish , Jha Babita , Jha Anal K.
Published: September 2019

Background::

At the present time, silver and gold nanoparticles are emerging as promising
agents for cancer therapy. The anticancer activities of these nanoparticles have been evaluated
against numerous human cancer cell lines. Still, few reports were existing against the breast cancer
cell lines and most of these studies have mainly used chemically mediated nanoparticles.

Objective::

This study reports the in vitro anticancer activity of bioinspired Nanoparticles like,
silver and gold against MCF-7 cells (breast cancer cell line) as well as HEK293 cell (human embryonic
kidney cell line) by MTT assay.

Methods:

These metal nanoparticles, Ag-NPs and Au-NPs were biologically synthesized using
Adiantum sp. aqueous leaves extract. The Adiantum sp. can reduce HAuCl4 solution to Au-NPs
and AgNO3 to Ag-NPs within 30 mins. The formation of NPs was confirmed by characterization
techniques such as UV-vis spectrophotometer, SEM and XRD studies. Additionally, the anticancer
activity was analysed by cell viability (3(4,5-dimethly-thiazol-2-yl)- 2,5-diphenyl tetrazo-lium
bromide assay).

Results:

The synthesized nanoparticles from Adiantum sp. were characterized by UV-visible spectroscopy.
The role of functional groups was analysed using a Fourier Transform Infrared (FTIR)
spectrophotometer. The XRD pattern clearly exemplified that the nanoparticles formed in this present
synthesis are crystalline in nature. Furthermore, in MTT assay study, both NPs have shown
cytotoxicity at different concentrations ranging from 2.5 to 100 μg/ml. The data reveal that the NPs
from Adiantum explicitly, inhibits the viability of cancerous cell only and are non-cytotoxic to
HEK293 cells in the tested concentration range.

Conclusion:

The results provide a preliminary guidance that Adiantum mediated silver and gold
nanoparticles might be used to treat breast cancer; however, it necessitates clinical studies to ascertain
their potential as anticancer agents.
Inorganic-organic Nanomaterials for Therapeutics and Molecular Imaging Applications
Authors: Aljabali Alaa A.A. , Obeid Mohammad A.
Published: September 2019

Background::

Surface modification of nanoparticles with targeting moieties can be
achieved through bioconjugation chemistries to impart new Functionalities. Various polymeric
nanoparticles have been used for the formulation of nanoparticles such as naturally-occurring
protein cages, virus-like particles, polymeric saccharides, and liposomes. These polymers have
been proven to be biocompatible, side effects free and degradable with no toxicity.

Objectives::

This paper reviews available literature on the nanoparticles pharmaceutical and medical
applications. The review highlights and updates the customized solutions for selective drug
delivery systems that allow high-affinity binding between nanoparticles and the target receptors.

Methods::

Bibliographic databases and web-search engines were used to retrieve studies that assessed
the usability of nanoparticles in the pharmaceutical and medical fields. Data were extracted
on each system in vivo and in vitro applications, its advantages and disadvantages, and its ability to
be chemically and genetically modified to impart new functionalities. Finally, a comparison
between naturally occurring and their synthetic counterparts was carried out.

Results::

The results showed that nanoparticles-based systems could have promising applications in
diagnostics, cell labeling, contrast agents (Magnetic Resonance Imaging and Computed Tomography),
antimicrobial agents, and as drug delivery systems. However, precautions should be taken
to avoid or minimize toxic effect or incompatibility of nanoparticles-based systems with the biological
systems in case of pharmaceutical or medical applications.

Conclusion::

This review presented a summary of recent developments in the field of pharmaceutical
nanotechnology and highlighted the challenges and the merits that some of the nanoparticles-
based systems both in vivo and in vitro systems.
Impact of the Precoagulation Performance of the Ultrafiltration Process in the Tertiary Treatment for Recycling of Urban Sewage
Authors: Lilia Mazari , Djamal Abdessemed
Published: September 2019

Background:

Ultrafiltration membrane processes have become an established
technology in the treatment and reuse of secondary effluents. Nevertheless, membrane fouling
arises as a major obstacle in the efficient operation of these systems.

Aim/Objective:

This study evaluates the factors affecting pretreatment conditions for combination
ultrafiltration membrane processes for reuse of secondary effluent from the sewage
treatment plant. The objective of this work is to study the precoagulation effect on the removal
of organic matter from secondary effluent from the wastewater treatment plant
Reghaïa (Algiers) and for fouling of the membranes ultrafiltration.

Methods:

A comparison was made between two coagulant FeCl3 and Fe2(SO4)3 using two
processing systems, Coagulation (with sedimentation) / Ultrafiltration and Coagulation
(without sedimentation) / Ultrafiltration. The optimum conditions for coagulation were determined
by the analysis UV254 and turbidity.

Result:

The results showed that there's a better reduction of the decrease of permeate flux
(Jv) in the coagulation system (without sedimentation)/Ultrafiltration for both coagulants
because of trapping of organic molecules responsible for fouling of the membrane inside the
porous flocs formed in the coagulation.
Multi-objective Charging and Discharging Optimization of Electric Vehicles in Time-divided period Based on SOC Evolution
Authors: Wang Ying , Ma Gang , Chen Yixi , Zhang Jian , Wang Jiashu
Published: September 2019

Background:

With the increase of Electric Vehicle (EV), their disordered charging behaviour
will put great pressure on the stable operation of the distribution network.

Methods:

In order to study the charging and discharging optimization scheme of EVs, firstly the EV
charging and discharging load model is founded based on the Vehicle-to-Grid (V2G) technology.

Results:

According to the electricity price mechanism of Shanxi Province, the paper proposes a
multi-target charging and discharging optimization for EVs based on the evolution of EV State of
Charge (SOC) using the Modified Particle Swarm Optimization (MPSO).

Conclusion:

Compared with the disordered charging mode, the method proposed in this paper can
simultaneously reduce the network loss of the distribution network and the cost of EV users.
"Green" Synthesis of Cerium Oxide Particles in Water Extracts Petroselinum crispum
Authors: Korotkova Аnastasia Mikhailovna , Borisovna Polivanova Oksana , Aleksandrovna Gavrish Irina , Bagdasarovna Kosyan Dianna , Vladimirovich Bagrov Dmitry , Vladimirovich Klinov Dmitry , Alexandrovich Fenin Anatoly , Yurievna Koroleva Marina , Nikolaevna Baranova Ekaterina , Aleksandrovich Ksenofontov Dmitry , Yurievich Cherednichenko Mikhail , Valerievich Lebedev Svyatoslav
Published: September 2019

Background:

Synthesis of metal oxides nanoparticles with specific morphology and size has become the subject of many experimental protocols. Biosynthesis of the nanoparticles using plants is more preferable than physical and chemical methods because of its environmental friendliness.

Objective:

The purpose of this study was to report the potential for green synthesis of cerium oxide nanoparticles using plant extracts with a high content of phenolic metabolites.

Methods:

We have synthesized the CeO2 nano- and microparticles using Petroselinum crispum aqueous extract. The particles were characterized by UV-visible spectroscopy, IR spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscope (TEM) and dynamic light scattering analysis. For detection the reduction capacity of the extract the evaluation of total phenolic and flavonoid content as well as high-performance liquid chromatography-mass spectrometry (HPLC-MS) were performed. Biological activity of the particles was identified by bioluminescent tests and bio tests with Triticum vulgare.

Results:

Testing on T. vulgare showed that biogenic cerium dioxide powders stimulated the growth of up to 5-11,4% relative to intact samples, significantly increased the length of the leaves of seedlings and the root length. When seedings were exposed to the biosynthesized CeO2 particles, the level of chlorophylls was more stable and even slightly higher than control. Noticeable protective properties of the biosynthesized CeO2 powder under oxidation conditions were observed on the plant T. vulgare after a brief exposure (from 4 to 24 h).

Conclusion:

Thus, biogenic CeO2 can be potentially utilized in oxidative damage protection of agricultural plants.
Heterogeneous Fenton Catalytic Removal of Organic Pollutant in Aqueous Solution by using Coal Gangue as a Catalyst
Authors: Zhang Jiwei , Xu Jingjing , Liu Shuaixia , Gu Baoxiang , Chen Feng , Zheng Qiming , Li Chaoyang
Published: September 2019

Background:

Coal gangue was used as a catalyst in heterogeneous Fenton process
for the degradation of azo dye and phenol. The influencing factors, such as solution pH
gangue concentration and hydrogen peroxide dosage were investigated, and the reaction
mechanism between coal gangue and hydrogen peroxide was also discussed.

Methods:

Experimental results showed that coal gangue has the ability to activate hydrogen
peroxide to degrade environmental pollutants in aqueous solution. Under optimal conditions,
after 60 minutes of treatment, more than 90.57% of reactive red dye was removed, and the
removal efficiency of Chemical Oxygen Demand (COD) up to 72.83%.

Results:

Both hydroxyl radical and superoxide radical anion participated in the degradation
of organic pollutant but hydroxyl radical predominated. Stability tests for coal gangue were
also carried out via the continuous degradation experiment and ion leakage analysis. After
five times continuous degradation, dye removal rate decreased slightly and the leached Fe
was still at very low level (2.24-3.02 mg L-1). The results of Scanning Electron Microscope
(SEM), energy dispersive X-Ray Spectrometer (EDS) and X-Ray Powder Diffraction (XRD)
indicated that coal gangue catalyst is stable after five times continuous reuse.

Conclusion:

The progress in this research suggested that coal gangue is a potential nature
catalyst for the efficient degradation of organic pollutant in water and wastewater via the
Fenton reaction.
The Impact of Racial Identity and Social Spaces on the Academic Experiences of Biracial Students: A Phenomenographic Study for School Administrative Intervention
Authors: R. Raagas Maria Judith
Published: September 2019

This study explored the identity and social spaces that affects academic performances, and behavioral difficulties of biracial students. As teachers have direct experiences with biracial students in every working days in school, these serve as an opportunity for the researcher to study the academic experiences of biracial learners. This research paper is qualitative research that used the phenomenographic approach. Phenomenography is investigative, and, explanatory as, it charts the different ways on how the participants understand, conceptualize, perceive and observe the different aspects of a phenomenon in the environment around them. The participants were grade school teachers wherein their experiences with the biracial students were explored. The researcher interviewed the participants, and the interviews were transcribed verbatim. As findings, five themes were drawn by the researcher from the interview. These are: classroom profile of biracial students, academic performances, behavioral difficulties, racial identity shaped by the parents and environment, and the intervention.
Preto lá faz faculdade? Uma revisão da literatura sobre racismo nas universidades brasileiras
Authors: Coelho Ingrid Mesquita , Lima Alves Rosemary Amanda , De Souza Daniel Cerdeira , Honorato Eduardo Jorge Sant'Ana
Published: September 2019

RESUMO Consideramos racismo, o sistema construído historicamente que, a partir da raça, classifica os sujeitos em inferiores e superiores. A partir desses constructos, negros foram colocados em um lugar de inferioridade por toda a história. Objetivamos discutir a incidência do racismo nas universidades brasileiras a partir de uma revisão de literatura em artigos científicos publicados entre 2012-2017 e elaboramos um protocolo para análise descritiva dos achados. Como resultados, percebemos a criação do sistema de cotas para o combate da desvantagem no acesso à universidade, mas poucas ações para o combate do racismo institucional que aflige essa população. O discurso meritocrático ainda é o principal argumento contra as cotas.   Palavras-chave: Racismo; Universidades Brasileiras; Desigualdades.     ABSTRACT We consider racism, the historically constructed system that, from the race, classifies the subjects into inferiors and superiors. From these constructs, blacks have been placed in a place of inferiority throughout history. We aim to discuss the incidence of racism in Brazilian universities based on a review of the literature in scientific articles published between 2012-2017 and elaborated a protocol for descriptive analysis of the findings. As results, we perceive the creation of the quota system to combat disadvantage in access to university, but few actions to combat institutional racism that afflicts this population. Meritocratic discourse is still the main argument against quotas.   Keywords: Racism; Brazilian Universities; Inequalities.   RESUMEN Consideramos racismo, el sistema construido históricamente que, a partir de la raza, clasifica a los sujetos en inferiores y superiores. A partir de esos constructos, negros fueron colocados en un lugar de inferioridad por toda la historia. Objetivamos discutir la incidencia del racismo en las universidades brasileñas a partir de una revisión de literatura en artículos científicos publicados entre 2012-2017 y elaboramos un protocolo para análisis descriptivo de los hallazgos. Como resultados, percibimos la creación del sistema de cuotas para el combate de la desventaja en el acceso a la universidad, pero pocas acciones para el combate del racismo institucional que aflige a esa población. El discurso meritocrático sigue siendo el principal argumento contra las cuotas.Palabras clave: Racismo; Universidades Brasileñas; Desigualdades.   DOI: http://dx.doi.org/10.22169/revint.v14i32.1563
Identifying Topical Coverages of Curricula using Topic Modeling and Visualization Techniques: A Case of Digital and Data Curation
Authors: Yang Seungwon , Ju Boryung , Chung Haeyong
Published: September 2019

Digital/data curation curricula have been around for a couple of decades. Currently, several ALA-accredited LIS programs offer digital/data curation courses and certificate programs to address the high demand for professionals with the knowledge and skills to handle digital content and research data in an ever-changing information environment.  In this study, we aimed to examine the topical scopes of digital/data curation curricula in the context of the LIS field.  We collected 16 syllabi from the digital/data curation courses, as well as textual descriptions of the 11 programs and their core courses offered in the U.S., Canada, and the U.K. The collected data were analyzed using a probabilistic topic modeling technique, Latent Dirichlet Allocation, to identify both common and unique topics. The results are the identification of 20 topics both at the program- and course-levels. Comparison between the program- and course-level topics uncovered a set of unique topics, and a number of common topics.  Furthermore, we provide interactive visualizations for digital/data curation programs and courses for further analysis of topical distributions. We believe that our combined approach of a topic modeling and visualizations may provide insight for identifying emerging trends and co-occurrences of topics among digital/data curation curricula in the LIS field.
Progress in Research Data Services
Authors: Cox Andrew M , Kennan Mary Anne , Lyon Elizabeth Josephine , Pinfield Stephen , Sbaffi Laura
Published: September 2019

University libraries have played an important role in constructing an infrastructure of support for Research Data Management at an institutional level. This paper presents a comparative analysis of two international surveys of libraries about their involvement in Research Data Services conducted in 2014 and 2018. The aim was to explore how services had developed over this time period, and to explore the drivers and barriers to change. In particular, there was an interest in how far the FAIR data principles had been adopted.

Services in nearly every area were more developed in 2018 than before, but technical services remained less developed than advisory. Progress on institutional policy was also evident. However, priorities did not seem to have shifted significantly. Open ended answers suggested that funder policy, rather than researcher demand, remained the main driver of service development and that resources and skills gaps remained issues. While widely understood as an important reference point and standard, because of their relatively recent publication date, FAIR principles had not been widely adopted explicitly in policy.
Experimental Data Curation at Large Instrument Facilities with Open Source Software
Authors: Pouchard Line , Kleese van Dam Kerstin , Campbell Stuart I
Published: September 2019

The National Synchrotron Light Source II operating at Brookhaven National Laboratory since 2014 for the US Department of Energy is one of the newest and brightest storage-ring synchrotron facility in the world.  NSLS-II, like other facilities, provides pre-processing of the raw data and some analysis capabilities to its users. We describe the research collaborations and open source infrastructure  developed at large instrument facilities such as NSLS-II for the purpose of curating high value scientific data along the early stages of the data lifecycle.  Data acquisition and curation tasks include storing experiment configuration, detector metadata, raw data acquisition with infrastructure that converts proprietary instrument formats to industry standards.  In addition, we describe a specific effort for discovering sample information at NSLS-II and tracing the provenance of analysis performed on acquired images.  We show that curation tasks must be embedded into software along the data life cycle for effectiveness and ease of use, and that loosely defined collaborations evolve around shared open source tools.  Finally we discuss best practices for experimental metadata capture in such facilities, data access and the new challenges of scale and complexity posed by AI-based discovery for the synthesis of new materials.
Laboratorio y taller virtual de proyectos (LTPV)
Authors: Ríos Barrios Waldo
Published: September 2019

El objetivo de este texto es destacar la importancia de introducir a los estudiantes en el proceso investigativo para favorecer el pensamiento científico, matemático y crítico, además de involucrarlos en la planificación y desarrollo de proyectos a partir de un espacio en línea creado para el trabajo en equipo. Un grupo de estudiantes del B@UNAM implementó una plataforma Moodle 3.4 que cuenta con herramientas de la Web 2.0 para el desarrollo de proyectos. Cabe decir que para desarrollar este tipo de proyectos con estudiantes de diferentes partes de la República Mexicana y del extranjero se establecía comunicación vía telefónica, videollamada y por correo electrónico, lo cual resultaba poco eficiente. Establecer una plataforma para integrar a los estudiantes del B@UNAM en una comunidad virtual que permite vincularlos entre sí y con asesores en línea crea una estrategia de iniciación temprana a la vida científica e investigativa. En estas páginas se presenta tanto el proceso de su diseño e instalación así como su pilotaje inicial.
Un esquema para planificar la enseñanza de la matemática
Authors: Rodríguez Mabel Alicia
Published: September 2019

La enseñanza de la matemática es una tarea compleja que requiere, de los docentes, conocimientos específicos que trascienden los de la propia disciplina. Entre ellos, se encuentran los referidos a la planificación de la enseñanza.
Esto abarca desde la toma inicial de decisiones hasta la evaluación de la propuesta, luego del trabajo en las clases. En este artículo nos centramos en la temática de la planificación de clases de matemática. Sabiendo que hay múltiples autores y posicionamientos al respecto, proponemos un esquema de trabajo y ejemplificamos
sus posibles usos, en particular en el entorno en línea.
Prosperar en una nueva sociedad del aprendizaje / LINC 2019
Authors: Bucio Jackeline
Published: September 2019

Del 17 al 20 de julio de 2019, se llevó a cabo el encuentro educativo LINC 2019 (Learning International Networks Consortium) en el Instituto de Tecnología de Massachusetts (MIT). El evento, organizado por el Laboratorio Mundial de Educación Abdul Latif Jameel (J-WEL) y el MIT Open Learning, convocó a investigadores de 31 países en torno al tema: cómo prosperar en una nueva sociedad de aprendizaje, en contextos de educación básica, educación superior y espacios de trabajo. Esta reseña presenta una síntesis de los puntos más importantes.
PECULIARITIES OF URGENT ADAPTATION OF MARINE SPECIALISTS OF CONSTRUCTION AND ACTIVE SHIPS AT MARINE OUTPUTS
Authors: Tyagnerev Aleksej T. , Ivanov Andrej O. , Groshilin Sergej M. , Shatov Dmitrij V. , Lobozova Oksana V. , Linchenko Sergej N. , Afendikov Sergej G.
Published: September 2019

At present, the number of ships under construction, repairing and upgrading, has increased and, accordingly, their marine outputs, which occur when there is an increased number of participants on board, which significantly impairs the habitability of the ship. In such cases, the dynamics of adaptation reactions of sailors to the conditions of navigation may differ from that on active ships and to a greater extent depend on the initial adaptation potential of the organism. This provision was the main hypothesis of the study performed. The purpose of the work is a comparative assessment of urgent adaptation of marine specialists of construction and active ships at marine outputs. Materials and methods. The control groups of 2 crews under construction ships (19 people) and 4 crews of active ships (36 people) were examined using a specially developed complex of clinical, physiological and psycho-physiological methods. The groups of seamen were divided into subgroups depending on the initial adaptation potential of the organism. Studies were conducted — in the pre-shipping period (1st stage); twice during the period of sailing — after 7 days from the moment of going to sea (2nd stage) and 3 days before the end of the voyage (3rd stage); and 4–6 days after returning to the base (4th stage). The results of research have shown the process of urgent adaptation among sailors of ships under construction, when going out to sea, is much more stressful and difficult than a similar process in the crews of operating ships. In addition, difficulties in adapting to the conditions of navigation are largely determined by the level of the initial adaptation potential of the organism, which can serve as a prognostic criterion for unacceptable deterioration in the working capacity of marine specialists. In this regard, it is extremely important not only to revise the existing labor regimes of the crews of ships under construction, repair and upgrade, but also to improve the measures of their medical (including physiological and psychophysiological) support.
COMBINED HYPOXIC AND PHYSICAL TRAININGS — EFFECTIVE MEANS OF EMERGENCY INCREASE OF PHYSICAL ENDURANCE OF SPECIALISTS WITH DIFFICULT WORKING CONDITIONS
Authors: Sklyarov Vadim N. , Nikolaenko Igor’ O. , Dmitriev Georgij V. , Kochubejnik Nikolai V. , Bygayan Svetlana E. , Eroshenko Andrei Y. , Stepanov Vlaimir A. , Kuzmin Arsenij V.
Published: September 2019

Introduction. Special conditions for the activity of specialists of the naval crews are often «forced» to function at the limit of the physiological capabilities of the body, requiring constant maintenance of a high level of physical working capacity. The purpose of the study is to evaluate the effectiveness of combined physical and normobaric hypoxic training for an emergency increase in the physical endurance of ship specialists and other representatives of «dangerous» occupations. Materials and methods. Were examined 18 men (10 people — the main group, 8 people — the control group) aged 19–22 years. The subjects of both groups performed workouts on exercise bikes: work power 1,2 W/kg, duration 2 hours, the total number of training sessions 14. For people of the main group, physical training was carried out under conditions of normobaric hypoxia created in the normobaric hypoxic complex, with an oxygen content of about 16% (15,9 kPa). In persons of the control group, hypoxia conditions were imitated: atmospheric air was supplied to the premises of the hypoxic complex. The physical endurance of the subjects was evaluated by the maximum oxygen consumption indicator. Results and its discussion. The studies revealed that the effectiveness of training in individuals of the main group turned out to be significantly higher compared to the control, as evidenced by the results of control tests of physical endurance, carried out both immediately after the training and in the long-term observation period. Thus, the method of combined physical and normobaric hypoxic training can be considered as an effective and safe means of emergency and persistent increase in physical endurance of ship specialists and of other categories of people with difficult and dangerous working conditions.
EFFICACY OF KAGOCEL IN NONSPECIFIC PREVENTION OF ACUTE RESPIRATORY VIRAL INFECTIONS AND INFLUENZA
Authors: Ozerova Irina V. , Malishev Nikolay A.
Published: September 2019

Acute respiratory viral infections (ARVI) are some of the most widely spread diseases worldwide that are of 80% of economic cost of infectious diseases. It is known that specific prophylaxis (vaccination) and, in some clinical cases, direct-acting antiviral prophylaxis are key strategies for the prevention of influenza as one of the most dangerous ARVI viruses. However, there are a number of reasons why specific prophylaxis of influenza does not entirely address the issue of prophylaxis of ARVI that are caused by more than 200 different viruses, such as formation of immune response only to vaccine influenza strains and absence of immune response to other respiratory infections, induction in the case of short-term protection, especially, in the aged and others. Prevention of influenza with antiviral drugs is limited by risks of development of resistant influenza strains aa well as contraindications and limitations of use. Therefore, the use of nonspecific drugs such as broad-spectrum antiviral drugs of interferon type (IFN) and their inducers (II), as well as sanitary and hygienic measures is recommended for prevention. For the purpose of prevention, the use of inducers of endogenic interferons is relevant in unvaccinated persons during pre-epidemic and epidemic ARVI periods; in high-risk group (students, medical professions, transport workers, elderly, patients with comorbid pathologies, people in structured organizations, for example, military personnel), in immunocompromised people. One of the most extensively studied interferon inducers widely used in clinical practice since 2003 for prevention and treatment of influenza and diseases caused by Herpesviruses is an antiviral drug Kagocel®. The paper presents real-time data of the preventive efficacy of Kagocel® in the therapy of acute respiratory viral infections and influenza caused by different viral strains including pandemic ones.
HERO OF THE SOVIET UNION, NURSE MARINE MARIYA TSUKANOVA
Authors: Chepik Georgiy S. , Karpova Tamara N. , Soldatov Ivan K.
Published: September 2019

The paper presents the biography of Mariya Tsukanova, marine, medical instructor and senior seaman in the 355 th Independent Guards Naval Infantry Battalion of the Pacific Fleet, her correspondence with parents, data of her military career, studies and work in Vladivostok, inauguration of memorial to Mariya Tsukanova on the territory of the Main Military Clinical Hospital of the Pacific Fleet and in Chongjin memorial military cemetery, Korea. Documentary evidence as a result of many years of searching of historical documentation has been used also. Mariya Tsukanova was awarded posthumously with Order of Lenin and she got the title Hero of the Soviet Union. The name of Mariya Tsukanova was immortalized in monuments, memorial plates, names of streets, villages, rivers and bays. Historical documentation and document evidence of Mariya Tsukanova are kept in libraries and museums of Leningrad, Abakan, Tomsk, Barnaul and Vladivostok.
Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study
Authors: Cardona Alexia , Day Felix R. , Perry John R.B. , Loh Marie , Chu Audrey Y. , Lehne Benjamin , Paul Dirk S. , Lotta Luca A. , Stewart Isobel D. , Kerrison Nicola D. , Scott Robert A. , Khaw Kay-Tee , Forouhi Nita G. , Langenberg Claudia , Liu Chunyu , Mendelson Michael M. , Levy Daniel , Beck Stephan , Leslie R. David , Dupuis Josée , Meigs James B. , Kooner Jaspal S. , Pihlajamäki Jussi , Vaag Allan , Perfilyev Alexander , Ling Charlotte , Hivert Marie-France , Chambers John C. , Wareham Nicholas J. , Ong Ken K.
Published: September 2019

Epigenetic changes may contribute substantially to risks of diseases of aging. Previous studies reported seven methylation variable positions (MVPs) robustly associated with incident type 2 diabetes mellitus (T2DM). However, their causal roles in T2DM are unclear. In an incident T2DM case-cohort study nested within the population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort, we used whole blood DNA collected at baseline, up to 11 years before T2DM onset, to investigate the role of methylation in the etiology of T2DM. We identified 15 novel MVPs with robust associations with incident T2DM and robustly confirmed three MVPs identified previously (near to TXNIP, ABCG1, and SREBF1). All 18 MVPs showed directionally consistent associations with incident and prevalent T2DM in independent studies. Further conditional analyses suggested that the identified epigenetic signals appear related to T2DM via glucose and obesity-related pathways acting before the collection of baseline samples. We integrated genome-wide genetic data to identify methylation-associated quantitative trait loci robustly associated with 16 of the 18 MVPs and found one MVP, cg00574958 at CPT1A, with a possible direct causal role in T2DM. None of the implicated genes were previously highlighted by genetic association studies, suggesting that DNA methylation studies may reveal novel biological mechanisms involved in tissue responses to glycemia.
Diabetic Nephropathy Alters the Distribution of Circulating Angiogenic MicroRNAs Among Extracellular Vesicles, HDL, and Ago-2
Authors: Florijn Barend W. , Duijs Jacques M.G.J. , Levels Johannes H. , Dallinga-Thie Geesje M. , Wang Yanan , Boing Anita N. , Yuana Yuana , Stam Wendy , Limpens Ronald W.A.L. , Au Yu Wah , Nieuwland Rienk , Rabelink Ton J. , Reinders Marlies E.J. , van Zonneveld Anton Jan , Bijkerk Roel
Published: September 2019

Previously, we identified plasma microRNA (miR) profiles that associate with markers of microvascular injury in patients with diabetic nephropathy (DN). However, miRs circulate in extracellular vesicles (EVs) or in association with HDL or the RNA-binding protein argonaute-2 (Ago-2). Given that the EV- and HDL-mediated miR transfer toward endothelial cells (ECs) regulates cellular quiescence and inflammation, we hypothesized that the distribution of miRs among carriers affects microvascular homeostasis in DN. Therefore, we determined the miR expression in EV, HDL, and Ago-2 fractions isolated from EDTA plasma of healthy control subjects, patients with diabetes mellitus (DM) with or without early DN (estimated glomerular filtration rate [eGFR] >30 mL/min/1.73 m2), and patients with DN (eGFR <30 mL/min/1.73 m2). Consistent with our hypothesis, we observed alterations in miR carrier distribution in plasma of patients with DM and DN compared with healthy control subjects. Both miR-21 and miR-126 increased in EVs of patients with DN, whereas miR-660 increased in the Ago-2 fraction and miR-132 decreased in the HDL fraction. Moreover, in vitro, differentially expressed miRs improved EC barrier formation (EV-miR-21) and rescued the angiogenic potential (HDL-miR-132) of ECs cultured in serum from patients with DM and DN. In conclusion, miR measurement in EVs, HDL, and Ago-2 may improve the biomarker sensitivity of these miRs for microvascular injury in DN, while carrier-specific miRs can improve endothelial barrier formation (EV-miR-21/126) or exert a proangiogenic response (HDL-miR-132).
Et Øst-Vest-skille for eldres livskvalitet i Europa? En sammenligning av ensomhet og depressive symptomer i 12 land
Authors: Hansen Thomas , Slagsvold Britt
Published: September 2019

Abstract: An East-West divide in late-life wellbeing in Europe? A comparative study of 12 countries  This study explores late-life loneliness and depression in European countries, noting the role of micro-level differences in socioeconomic status, health, and social variables. Findings from cross-sectional, nationally representative data from 12 countries and 36,000 individuals in the Generations and Gender Survey show a marked East–West divide among older but not among younger adults. Among older adults (aged 60–80) loneliness and depression are as much as three to four times more prevalent in Eastern European (20–40%) than in Northwest European countries (10–15%). These patterns reflect economic, social, and societal issues which in turn affect the conditions for active and healthy aging. There is considerable variation among Eastern European countries, correlating with macro-level economic development and welfare spending. Generous welfare states seem to offer a buffer against, or postpone, the risk of late-life depression and loneliness. Cultural factors may also play a role: because of high expectations as to strong family and community ties, Eastern Europeans may have a lower loneliness threshold than other Europeans.
PENGEMBANGAN E-LEARNING SEBAGAI PERANGKAT BLENDED LEARNING UNTUK PELAKSANAAN DIKLAT PENYUSUNAN BAHAN AJAR DI BALAI PENDIDIKAN DAN PELATIHAN KEAGAMAAN DENPASAR
Authors: Ahmad Hisan
Published: September 2019

Penelitian ini bertujuan untuk menghasilkan produk pembelajaran berupa e-learning sebagai perangkat blended learning yang valid, praktis, dan efektif dalam pelaksanaan diklat penyusunan bahan ajar di Balai Diklat Keagamaan Denpasar. Penelitian pengembangan ini didasari karena masih kurangnya ragam media dan bahan pembelajaran yang digunakan pada pelaksaan diklat, metode pembelajaran yang diterapkan masih bersifat konvensional dan masih terbatasnya komunikasi antara widyaiswara dengan peserta diklat. Prosedur pengembangan menggunakan model ADDIE yang terdiri dari lima tahap yaitu: (1) analysis, (2) design, (3) development, (4) implementation, dan (5) evaluation.Hasil penelitian menunjukkan e-learning yang dikembangkan telah memenuhi aspek validitas, kepraktisan, dan efektivitas. Hasil uji validitas menunjukkan bahwa e-learning sebagai perangkat blended learning berada pada kategori sangat baik berdasarkan uji coba para ahli. E-learning juga telah memenuhi aspek kepraktisan dilihat dari respon peserta terkait kemudahan penggunaan dan kemenarikan antarmuka. Hasil uji-t menunjukkan, terdapat perbedaan yang signifikan antara nilai rata-rata hasil diklat penyusunan bahan ajar peserta diklat sebelum dan setelah menggunakan e-learning sebagai perangkat blended learning, di mana nilai rata-rata posttest lebih lebih besar dari nilai rata-rata pretest dan telah mencapai kriteria keberhasilan. Berdasarkan hal tersebut, e-learning sebagai perangkat blended learning dinilai efektif dalam meningkatkan hasil diklat penyusunan bahan ajar.
Students’ Spatial Reasoning in Solving Geometrical Transformation Problems
Authors: Evidiasari Serli , Subanji Subanji , Irawati Santi
Published: September 2019

This study describes spatial reasoning of senior high school students in solving geometrical transformation problems. Spatial reasoning consists of three aspects: spatial visualization, mental rotation, and spatial orientation. The approach that is used in this study is descriptive qualitative. Data resource is the test result of reflection, translation, and rotation problems then continued by interview. Collecting data process involves 35 students. They are grouped to three spatial reasoning aspects then selected one respondent to be the most dominant of each aspect. The results of this study are: (1) the students with spatial visualization aspect used drawing strategy and non-spatial strategy in solving geometrical transformation problems. She transformed every vertex of the object and drew assistance lines which connect every vertex of the object to center point; (2) the students with mental rotation aspect used holistic and analytic strategies in solving geometrical transformation problems. Using holistic strategy means imagining the whole of transformational objects to solve easy problems. While using analytic strategy means transforming some components of objects to solve hard problems; (3) the students with spatial orientation didn’t involve mental imagery and she only could determine the position and orientation of the object in solving geometrical transformation problems
PRESTASI BELAJAR AKUNTANSI MELALUI MODEL PEMBELAJARAN PROBLEM BASED LEARNING PADA SISWA KELAS XI MA AL HIDAYAH MUARA TELANG KABUPATEN BANYUASIN
Authors: Dewi AR Ratna , Thahir Musa
Published: September 2019

Penelitian ini dilatarbelakangi oleh minat dan motivasi siswa untuk belajar akuntansi masih rendah, baik motivasi internal maupun motivasi eksternal. Berdasarkan masalah yang ada, penelitian ini bertujuan untuk mendeskripsikan penerapan model pembelajaran Problem Based Learning dalam meningkatkan prestasi belajar akuntansi pada siswa kelas XI MA Al Hidayah Muara Telang Kabupaten Banyu Asin. Metode penelitian ini menggunakan pendekatan Penelitian Tindakan Kelas (PTK).  Dalam Penelitian Tindakan Kelas (PTK) ini yang menjadi subjek penelitian adalah siswa kelas XI IPS yang terdiri dari 37 siswa. Teknik yang digunakan dalam penelitian ini adalah observasi, dokumentasi, dan tes. Sedangkan analisis data yang digunakan adalah analsis data deskriptif komparatif, dan analsis kualitatif.  Hasil penelitian menunjukkan bahwa secara keseluruhan penerapan model Problem Based Learning telah dapat meningkatkan prestasi belajar siswa. Hal ini terbukti dari pencapaian nilai rata-rata siswa dan jumlah siswa yang mencapai batas ketuntasan.
Hubungan antara Komunikasi Keluarga dan Pencegahan Penyalahgunaan Narkoba Pada Siswa Kelas VIII SMPN 2 Rambah Samo Kabupaten Rokan Hulu Provinsi Riau
Authors: Anita Defri
Published: September 2019

In writing this article the author chose a study entitled The Relationship Between Family Communication and Narcotics Abuse Prevention in Class VIII Students of SMPN 2 Rambah Samo, Rokan Hulu Regency, Riau Province.cThis study aims to describe the picture of family communication of students of SMPN 2 Rambah Samo, Rokan Hulu District, Riau Province; describe prevention of drug user students in Rambah Samo 2 Public High School, Rokan Hulu Regency, Riau Province; and knowing whether or not there is a relationship between family communication and prevention of drug abuse students at Rambah Samo 2 Middle School, Rokan Hulu District, Riau Province. This study addresses two variables, namely family communication and prevention of drug abuse. class VIII SMP 2 Rambah Samo Riau Province Rokan Hulu District Academic Year 2013/2014 which amounted to 143 students. then the sample used is 25% of the number of students, which is 25% x 143 = 36 students. The sampling technique used by researchers is a random sample. The type of research used in this study was post facto research or referred to after the fact. Data collection techniques used were documentation, observation, and questionnaires.The results showed that the quality of family communication was good, and prevention of drug abuse was also good. Thus, it can be stated that in general it is in a fairly good and good category. Based on the results of the calculation, it was found that the significance value was 0,000 which was smaller than the value of a = 0.05 and the calculated value was 0.371 in the "medium" category. The price coefficient is then tested for significance by comparing rtable to n = 80 at level 5%, then rtable = 0.220, where the value of r count> r table (0.371> 0.329) and the significance value obtained is less than 0.05. Thus, Ha is accepted namely there is a relationship between family communication and prevention of drug abuse students of the Middle School Rambah Samo 2, Rokan Hulu District, Riau Province. While the contribution of family communication and prevention of drug abuse amounted to 17.76%.
Pengaruh Lingkungan Negatif Terhadap Kedisiplinan Siswa SD Negeri 134 Pekanbaru
Authors: Yuliastuti Y. , Vebrianto Rian
Published: September 2019

Penelitian ini bertujuan untuk mengatahui  seberapa besarnya Pengaruh lingkungan n negatif pada  Pelaksanaan Tata Tertib Sekolah terhadap Kedisiplinan belajar Siswa. Tujauannya untuk meningkatkan kedisiplinan siswa – siswa serta melaksanakan tatatertib sekolah dengan baik.SD Negeri 134 Pekanbaru .Metode yang digunakan adalah Mix Methode Penelitian dilaksanakan   di Sekolah Dasar Negeri 134 Pekanbaru , dengan teknik pengambilan sampel secara simple random sampling dan wawancara didapat sampel sebanyak 20 orang siswa dari kelas 4,5 dan 6. Instrumen tata tertib dan kedisiplinan belajar siswa berupa lembar pertanyaan (angket) yang disebarkan kepada responden.Hipotesis yang diajukan adalah terdapat pengaruh lingkungan negative terhadap tata tertib sekolah yang signifikan terhadap kedisiplinan belajar siswa.Analisis data  variable terikat dan variable terbuka  .Hasil analisis penelitian deskritif menunjukan bahwa 1) pengaruh lingkungan keluarga sangat berperan penting dalam menanamkan kedisipilan anak , 2) pengaruh lingkungan masyarakat yaitu lingkungan negatif  di sekitar rumah menjadi kendala dalam penerapan kedisiplinan di sekolah,  3) pengaruh pelaksanaan tata tertib sekolah terhadap kedisiplinan siswa di SD Negerin 134 Pekanbaru .artinya  jika baik  pengaruh lingkungan  keluarga dan masyarakat  maka  penerapan kedisiplinan  dan tata tertib yang ada di sekolah akan mudah di terapakan, kediisiplinan berpengaruh kepada pelaksanaan tata tertib sekolahserta  terhadap kedisiplinan belajar siswa.
PEMBELAJARAN IPA BERBASISKAN INTEGRASI INKUIRI TERBIMBING DENGAN NUMBERED HEADS TOGETHER (NHT) DALAM MENINGKATKAN MOTIVASI BELAJAR
Authors: Syafaren Alaniyah , Yustina Yustina , Mahadi Imam
Published: September 2019

Penelitian ini bertujuan untuk mengetahui pengaruh pembelajaran IPA berbasiskan integrasi inkuiri terbimbing dengan Numbered Heads Together (NHT) terhadap motivasi belajar siswa. Jenis penelitian ini adalah penelitian quasi eksperimen, dengan design penelitian non equivalen control grup design. Penelitian dilaksanakan pada bulan September-Desember tahun pelajaran 2018 dengan sampel kelas eksperimen berjumlah 40 siswa dan kelas kontrol berjumlah 40 siswa pada kelas VIII SMP N 21 Pekanbaru. Instrumen penelitian berupa angket motivasi belajar. Motivasi belajar dalam penelitian ini terdiri atas: hasrat, dorongan, harapan, penghargaan dan menarik. Hasil penelitian ini ini menunjukkan bahwa terdapat perbedaan yang signifikan pada nilai rata-rata post test motivasi belajar peserta didik antara kelas eksperimen sebesar 3.26 dibandingkan kelas kontrol sebesar 3.12 setelah dilaksanakan intervensi (P<0,05). Hal ini jelas bahwa penggunaan  integrasi inkuiri terbimbing dengan NHT dalam proses pembelajaran dapat meningkatkan motivasi belajar peserta didik. Implikasi dari penelitian ini adalah memberikan salah satu alternative proses pembelajaran yang kreatif dan inovatif dalam meningkatkan motivasi belajar peserta didik.
Penerapan Model Pembelajaran LC 7E Dengan Pendekatan TBCT dan CT untuk Meningkatkan Kemampuan Memahami Siswa
Authors: Miadi Okta , Kaniawati Ida , Ramalis Taufik Ramlan
Published: September 2019

Penelitian ini bertujuan untuk melakukan kajian terkait peningkatan kemampuan memahami siswa pada konsep fluida statis setelah diberikan perlakuan dengan model pembelajaran learning cycle 7E dengan pendekatan Technology Based Constructivist Teaching dan Constructivist Teaching. Metode penelitian yang digunakan adalah Quasi Experiment dengan desain Pretest Posttest Two Equivalent Group Design. Subyek penelitian adalah 29 orang siswa kelas XI IPA 1 dan 27 orang siswa XI IPA 2 di salah satu SMA Negeri di Kab. Kuantan Singingi, Prov. Riau. Instrumen penelitian yang digunakan adalah tes kemampuan kognitif berbentuk tes tertulis jenis pilihan ganda terkait konsep fluida statis. Hasil penelitian menunjukkan bahwa setelah dilakukan penerapan model pembelajaran learning cycle 7E dengan pendekatan TBCT dan CT, hasil kemampuan memahami siswa secara umum meningkat pada kelas eksperimen sebesar 0,71 dengan kategori tinggi dan kelas kontrol sebesar 0,65 dengan kategori sedang.
GERAKAN MUSLIM PROGRESIF PASCA REJIM SUHARTO DI INDONESIA
Authors: Suaedy Ahmad
Published: September 2019

Di luar tumbuhnya berbagai gerakan Islam radikal dan fundamentalis paska tumbangnya Orde Baru, muncul pula gerakan Muslim progresif. Sebuah gerakan yang mengusung berbagai isu substansial untuk demokrasasi seperti pluralisme dan toleransi, hak-hak perempuan dalam Islam dan keadilan, atau hak-hak asasi manusia pada umumnya. Sebagian mereka tumbuh berkat keterbukaan politik di era reformasi, tetapi sebagian lainnya merupakan penjelmaan dari gerakan underground di era orde baru yang mengusung demokratisasi dengan titik masuk Islam. Kini mereka trerbangun jaringan kerja baik dalam level isu untuk mempertajam dan menggugat konsep-konsep konvesional tentang Islam mengiringi perubahan sosial politik, maupun dalam prkatik politik itu sendiri untuk menjaga sustainabilitas demokrasi. Bagaimanakah jaringan itu terbangun, bagaimana cara kerja mereka, isu apa saja yang mereka usung dan apa kelebihan dan kekuranagnnya, serta bagaimana prospek gerakan ini? Itulah beberapa masalah pokok yang hendak disajikan dalam presentasi ini