bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of Smoothed Particle Hydrodynamics Method for Tsunami Force Modeling on Building with Openings
Authors: Anggita Putra , Triatmadja Radianta , Yuwono Nur
Published: January 2024

Smoothed Particle Hydrodynamics (SPH) serves as a numerical technique extensively employed for simulating free surface flow. The computational intricacy of the SPH method arises from the numerous computations of a particle's properties, derived from interactions with surrounding particles. To address this complexity, experts developed DualSPHysics. This study employs the SPH method, specifically the DualSPHysics application, for tsunami modeling. To accurately represent tsunami characteristics, precise numerical parameters are essential for numerical modeling. This research provides valuable insights into optimizing numerical parameters for accurate SPH simulations. Therefore, the research aims to identify the exact values of crucial parameters in DualSPHysics model. Validation of numerical calculations involves comparing the tsunami forces, as simulated by DualSPHysics, with secondary data obtained from physical experiments results. The findings highlight the significance of particle size (dp) as a crucial numerical parameter in DualSPHysics modeling. A smaller particle size contributes to model’s accuracy. The determination of the particle size must account for model’s shortest characteristic (s). According to simulations those have been carried out, it is recommended to set the maximum limit value of dp/s at 1/3.67 to achieve precise calculation. Furthermore, the DualSPHysics simulation demonstrates a reduction in force due to the opening configuration (n).
Studies of Improving Drinking Water Quality in the Kalurahan Banaran Kabupaten Kulon Progo Using Porous Concrete Filter
Authors: Arviananda Rr. Dita , Kamulyan Budi , Nurrochmad Fatchan
Published: January 2024

Some citizens of the Kalurahan Banaran Kabupaten Kulon Progo everyday use water that has an iron content (Fe) of 8.8 mg/L and a turbidity of 120 NTU, which is above the limit set by the Minister of Health’s Regulation RI Number: 2 Tahun 2023 on the Quality Requirements of Drinking Water. To solve this problem, research has been conducted to reduce Fe and turbidity by using porous concrete filters. Three models of porous concrete A (porousity 0.42), B (porousity 0.44), and C (porousity 0.46), were used to filter water samples using two aerator diffusers at speeds of 3 L/h and 6 L/hour on each porous concrete filter. The results of the study showed that at an aeration rate of 3 L/hour, there had been a successive decrease in turbidity and Fe from 14.9 NTU to 1.38 NTU and 1.64 mg/L to 0.14 mg/L (filter A); 80 NTU to 0.5 NTU and 6.55 mg/L to 0.02 mg/L (filter B); 80 NTU to 0.1 NTU and 6.5 mg/L to 0 mg/L (filter C). For an aeration rate of 6 L/hour, there had been a successive decrease in turbidity and Fe from 80 NTU to 0.82 NTU and 6.55 mg/L to 0.05 mg/L (filter A); 89.8 NTU to 0.28 NTU, and 7.8 mg/L to 0.01 mg/L (filter B); 80 NTU to 0.28 NTU and 6,55 mg/L to 0 mg /L (filter C). The results show that the porous concrete filter can be considered an alternative to drinking water treatment in the Kalurahan Banaran Kabupaten Kulon Progo.
A Voice-Activated Device Exercise and Social Engagement Program for Older Adult–Care Partner Dyads: Pilot Clinical Trial and Focus Group Study Evaluating the Feasibility, Use, and Estimated Functional Impact of EngAGE (Preprint)
Authors: Huisingh-Scheetz Megan , Nicholson III Roscoe F , Shervani Saira , Smith Chelsea , Danilovich Margaret , Finch Laura , Montoya Yadira , Hawkley Louise C
Published: January 2024

BACKGROUND

Maintaining exercise is essential for healthy aging but difficult to sustain. EngAGE is a socially motivated exercise program delivered over a voice-activated device that targets older adult–care partner dyads.

OBJECTIVE

This 10-week pilot study aimed to assess EngAGE feasibility and use, obtain user experience feedback, and estimate potential impact on function.

METHODS

In total, 10 older adults aged ≥65 years were recruited from an independent living residence together with their self-identified care partners. EngAGE delivered National Institute on Aging Go4Life exercises to older adults daily, while care partners received progress reports and prompts to send encouraging messages that were read aloud by the device to the older adult. Older adults’ use was tracked, and physical function was assessed at baseline and follow-up. Follow-up focus group data provided qualitative feedback.

RESULTS

On average, participants completed 393.7 individual exercises over the 10-week intervention period or 39.4 exercises/wk (range 48-492, median 431, IQR 384-481, SD 112.4) without injury and used EngAGE on an average of 41 of 70 days or 4.1 d/wk (range 7-66, median 51, IQR 23-56, and SD 21.2 days). Mean grip strength increased nonsignificantly by 1.3 kg (preintervention mean 26.3 kg, SD 11.0; postintervention mean 27.6 kg, SD 11.6; P=.34), and 4 of 10 participants improved by a minimal clinically important difference (MCID) of 2.5 kg. Further, the time for 5-repeated chair stands significantly reduced by 2.3 seconds (preintervention mean 12, SD 3.6 s; postintervention mean 9.7, SD 2.7 s; P=.02), and 3 of 9 participants improved by an MCID of –2.3 seconds. Furthermore, 3-meter usual walk performance was brisk at baseline (mean 2.1, SD 0.4 s) and decreased by 0.1 seconds (postintervention 2, SD 0.4 s; P=.13), although 5 of 9 participants improved by a MCID of 0.05 m/s. Qualitative results showed perceived benefits, favored program features, and areas for improvement.

CONCLUSIONS

We present a pilot study of a new voice-activated device application customized to older adult users that may serve as a guide to other technology development for older adults. Our pilot study served to further refine the application and to inform a larger trial testing EngAGE’s impact on functional outcomes, a necessary step for developing evidence-based technology tools.
Role of Diuretics in Cardiovascular Events and Mortality in Systolic Blood Pressure Intervention Trial
Authors: Bansal Shweta , Boucher Robert , Shen Jincheng , Wei Guo , Chertow Glenn M. , Whelton Paul K. , Cushman William C. , Cheung Alfred K. , Beddhu Srinivasan ,   , on behalf of SPRINT
Published: January 2024

Background

In a post hoc analysis, we examined whether postrandomization diuretics use can explain and/or mediate the beneficial effects of intensive systolic BP lowering on cardiovascular disease and all-cause mortality in the Systolic Blood Pressure Intervention Trial (SPRINT).

Methods

SPRINT was a randomized, controlled trial of 9361 participants comparing the effects of intensive (systolic BP target <120 mm Hg) versus standard (systolic BP target <140 mm Hg) BP control on a primary composite cardiovascular end point in participants aged 50 years or older with systolic BP of 130–180 mm Hg. In time-varying multivariable Cox analyses, we assessed hazard ratios (HRs) of cardiovascular end points and all-cause mortality in participants on thiazide type, loop and/or potassium (K) sparing, or no diuretics. We also conducted mediation analysis to formally assess the role of diuretics in the effects of intensive systolic BP lowering.

Results

At baseline, diuretics were prescribed in 46% and 48% of participants in standard and intensive systolic BP-lowering groups, respectively, and in 46% and 74% in the corresponding groups during the trial. The lower risk of cardiovascular end points in the intensive group (HR, 0.75; 95% confidence interval [CI], 0.64 to 0.89) persisted after adjustment for postrandomization time-varying diuretics use (HR, 0.74; 95% CI, 0.62 to 0.89). Across the entire study population, time-varying diuretics use was not associated with cardiovascular end points (compared with no diuretics, HR for thiazide type, 0.89; 95% CI, 0.73 to 1.10, and loop/K sparing, 1.29; 95% CI, 0.97 to 1.73). However, thiazide-type diuretics were associated with lower risk of cardiovascular end points in the intensive (HR, 0.62; 95% CI, 0.46 to 0.85) but not in the standard (HR, 1.07; 95% CI, 0.82 to 1.39) group. In mediation analysis, HRs for total effect, direct effect (not mediated through diuretics use), and indirect effect (mediated through diuretics) of the intervention on cardiovascular end points were 0.66 (95% CI, 0.54 to 0.79), 0.67 (95% CI, 0.54 to 0.81), and 0.98 (95% CI, 0.88 to 1.10), respectively. The results were largely similar for all-cause mortality.

Conclusions

The favorable effects of intensive systolic BP lowering on cardiovascular end points and all-cause mortality in SPRINT were independent of and not mediated by time-varying diuretics use. However, thiazide-type diuretics use associated with benefit if intensive systolic BP lowering was targeted.
A Corpus-based Study on Concessive Clauses Used in English Writing by Chinese Senior High School Students
Authors: Xu Haoran
Published: January 2024

This paper is designed to reveal the characteristics and figure out the errors in Chinese senior high students’ construction of concessive clause. The study uses data from Chinese Learner English Corpus (CLEC) and a collection of concessive clauses from 499 English compositions written by senior two students in a key public high school in Beijing. The result shows that the construction of concessive clauses exhibits certain characteristics: (1) employing a wide range of linking words, “although” being the most frequently used concessive conjunction, which differs from the use of linking words in St2 from CLEC; (2) having a tendency to place the subordinate clause before the matrix and to construct the concessive clause as “Subject + Linking Verb + Predicate”. Fifty-seven errors are identified in 132 concessive clauses, including: (1) errors of linking words; (2) the wrong matrix-subordinate clause relationship; (3) errors such as choosing the wrong linking words, inconsistent tense between the matrix and subordinate clauses, errors within the clauses, and incorrect use of punctuation. These errors are mainly influenced by the negative transfer from Chinese.
Multi-criteria analysis of the environmental vulnerability of the cotton zone of Mali: Case of the northeast subsidiary of Koutiala
Authors: Barry Tahirou , Diawara Hamidou , Sidi Traoré Souleymane , Attoubounou Rachid Abdourahamane
Published: January 2024

The northeast subsidiary of Koutiala is a very ancient and important cotton production zone in Mali. Commonly called old cotton basin of Mali, this subsidiary counting ten sectors divided between two divisions, is today finds confronted to environmental problems. However, it is difficult to locate the essential reasons of this problem so much the factors are numerous. To assess the impact of different factors on environment, this study devoted itself as objective to analyze the spatiotemporal dynamics of the environmental vulnerability of the northeast subsidiary of Koutiala between 2003 and 2017. It used several types of data for this purpose (climatic, satellite, socioeconomic and demographic, geographical). The used methodology was based on the Principal Component Analysis (PCA) and the Agglomerative Hierarchical Clustering (AHC), after standardizing the data using the empirical normalization method. The study reveals that the main factors of environmental vulnerability are mainly composed of indicators of occupation of the soil (NDVI and Occupancy rate of the soil by cultures which are present in 100.0% of the factors), socioeconomic (in 83.3%), climatic (in 66.7%) and socio-demographic (in 58.3%). It also reveals that the sector of Konséguéla in the southwest (division of Koutiala) is the least vulnerable contrary to that from Kimparana to the north (division of San) which is the most vulnerable. Globally between 2003 and 2017, there is a downward trend of the environmental vulnerability of the northeast subsidiary of Koutiala.
Herbal Medicine for Sarcopenia: A Systematic Review of Randomized Controlled Trials
Authors: Chun Se-eun , Lee Soo-hyung , Shin Yong-jeen , Shin Sun-ho
Published: January 2024

Objectives: Sarcopenia is an age-associated skeletal muscle disorder that can profoundly impact the health of elderly people. However, the efficacy of herbal medicine in sarcopenia is uncertain. This review aims to investigate evidence of the effect of herbal medicine on sarcopenia.Methods: We systematically searched 12 electronic databases for relevant randomized controlled trials (RCTs). Only trials that met the inclusion criteria were selected, and the characteristics of the included studies were extracted and synthesized in a narrative manner. The quality of the included studies was assessed using Cochrane’s Risk of Bias (RoB) 2.0 tool.Results: 7 RCTs involving 672 participants with sarcopenia met the inclusion criteria. The intervention combining herbal medicine and conventional treatment (i.e., exercise, nutritional support) had a significant therapeutic effect compared with the conventional treatment, showing improvement in muscle strength (i.e., grip strength), muscle mass (i.e., appendicular skeletal muscle mass index), and physical function (i.e., gait speed, short physical performance battery, and timed up and go test). However, the methodological quality of the included RCTs was relatively low due to their high RoB, making it difficult to evaluate the efficacy of herbal medicine in sarcopenia. In terms of safety, several adverse events were reported.Conclusion: This review suggests that herbal medicine has a positive effect on muscle strength, muscle mass, and physical performance in elderly patients with sarcopenia, but there is a clear need for further research in this area.
Herbal Medicine for the Treatment of Non-Erosive Reflux Disease: A Systematic Review and Meta-Analysis Protocol
Authors: Kim Minjeong , Park Chaehyun , Park Jae-Woo , Kim Jinsung , Ko Seok-Jae
Published: January 2024

Introduction: Non-erosive reflux disease (NERD) is the most common subtype of gastroesophageal reflux disease (GERD). This study aims to synthesize evidence on the efficacy and safety of various herbal medicines for the treatment of NERD.Methods and analysis: Ten electronic databases will be examined: MEDLINE (via PubMed), Cochrane Central Register of Controlled Trials, Embase, Allied and Complementary Medicine Database, China National Knowledge Infrastructure Database, Citation Information by Nii, Korean Medical Database, Korean Studies Information Service System, National Digital Science Library, and Oriental Medicine Advanced Searching Integrated System. All randomized controlled trials published from inception to May 2023 that meet the eligibility criteria will be selected. Two independent researchers will extract data, such as publication year, study design, intervention details, outcome measures, main results, and adverse events. The risk of bias and quality of evidence will be assessed, and subgroup analyses will be performed according to the type of control intervention and herbal medicine. The analysis process will be conducted using Review Manager 5.4 software.Discussion: This review will present a summary and rationale for herbal medicine’s effectiveness in treating NERD. The findings of this review can help those who want to apply herbal medicine to the treatment of NERD.

Systematic review registration:
 PROSPERO registration number CRD42023423052.
A Review of Recent Domestic Research on Herbal Medicine Treatments for Ulcerative Colitis: A Focus on OASIS Platform Research
Authors: Choi Sae-rom , Lee Ji-yoon , Park Sang-min , Shin Jae-wook , Baek Jee-hoon , Lee Min-ju , Lee Eun-jee
Published: January 2024

Objectives: This study analyzes domestic research trends on herbal medicine treatments for ulcerative colitis (UC) by examining 28 selected domestic papers using the Oriental Medicine Advanced Searching System (OASIS) as the main search source.Methods: A total of 28 domestic papers were selected on the OASIS platform as the main search source using the keywords “(궤양성 대장염) or (궤양성 대장병)" and “(한약) or (한의학)”.Results: There were 11 case report studies and 17 case-control studies published from 2002 to 2022. All the case-control studies only dealt with mice and did not include human subjects. The most common pathologies were damp heat and Changpung. Hwangryunhaedok-tang was the most frequently prescribed herbal formula, and Coptidis Rhizoma was the most commonly used herb across all studies. The results showed that many studies demonstrated the significant effects of herbal treatment.Conclusion: Herbal medicine may exhibit therapeutic effects on various aspects of UC. However, evidence-based studies, such as clinical trials involving human subjects, are needed.
A Case Report of Occipital Neuralgia Treated with Acupuncture in the Occipital Nerve Area
Authors: Kim Min-hwa , Nam I-rang , Kim Mariah , Ku Ki-beom , Lee Se-yeon , Kwon Jung-nam , Lee In , Choi Jun-yong , Yun Young-ju , Kim So-yeon , Han Chang-woo , Park So-jung , Hong Jin-woo
Published: January 2024

This case report presents the effectiveness of Korean medicine in the treatment of occipital neuralgia. The patient with occipital neuralgia was treated with acupuncture. Acupuncture treatment was administered to the occipital nerve area, which is commonly used in occipital nerve blocks by western medicine doctors. The severity of the symptoms was assessed daily using the Numerical Rating Scale (NRS) score of pain. The patient received outpatient treatment a total of 7 times, and only received acupuncture treatment each time. According to the patient, his symptoms decreased by about 90% two days after acupuncture treatment, and the frequency and duration of the symptoms also decreased. Seven days after all acupuncture treatments, the severity of pain was reduced from NRS 6 to NRS 0. The findings of this case report suggest that treatment with Korean medicine can be an effective option for treating occipital neuralgia. Acupuncture can be a good treatment method for occipital neuralgia, along with western drug treatment and occipital nerve block.
A Case Report on Korean Medicine Treatment for a Patient Diagnosed with Acute Gastric Mucosal Lesion on Ultrasound Imaging
Authors: Kim Chae-eun , Baek Tae-hyun
Published: January 2024

Objectives: This study reports a clinical case that showed improvement in the symptoms of a patient with acute gastric mucosal lesion (AGML) through ultrasound.Methods: A 90-year-old woman with AGML was treated with Korean medicine treatments, including Hyangsapyeongwisan Soft Ext, acupuncture, and moxibustion. The responses before and after treatment were evaluated using ultrasound imaging and the numerical rating scale (NRS).Results: After treatment, ultrasound imaging showed improvement in gastric mucosa thickness, from 1.45 cm to 0.53 cm at the anterior wall and from 1.25 cm to 0.36 cm at the posterior wall. The NRS scores for epigastric pain, nausea, and dizziness all decreased, and the symptoms of diarrhea disappeared.Conclusion: This study suggests that Korean medicine treatment can be a therapeutic option in treating the symptoms of patients with AGML.
Pengaruh Kualitas Pelayanan Pramusaji dan Fasilitas Terhadap Kepuasan Pelanggan Restoran
Authors: Dewi Sang Ayu Made Sintya , Amir Firlie Lanovia , Suarmana I Wayan Restu , Paramitha Made Widya
Published: January 2024

Adiwana Arya Villa di Ubud memiliki Wayang Restoran. Departemen layanan F&B selalu melakukan briefing sebelum melakukan jobdesk masing-masing untuk menjaga kualitas layanan dan keberadaan restoran. Tujuan dari penelitian ini adalah untuk menentukan tingkat kepuasan pelanggan di Wayang Restaurant di Adiwana Arya Villa dipengaruhi oleh kualitas pelayanan pramusaji dan fasilitas yang tersedia. Studi ini dilakukan menggunakan pendekatan deskriptif kuantitatif yang menggunakan statistik. Data dikumpulkan melalui pengisian kuesioner dari 99 orang yang makan di Wayang Restoran Adiwana Arya Villa. Analisis data menggunakan regresi linier berganda. Hasil penelitian menunjukkan bahwa faktor kualitas layanan pramusaji sangat memengaruhi kepuasan pelanggan. Nilai t-tabel sebesar 1,985 kurang dari nilai t-hitung sebesar 2,134, menunjukkan hal ini. Karena itu, hipotesis kedua (H2) tidak valid. Secara keseluruhan, dapat disimpulkan bahwa dalam model penelitian ini, kualitas pelayanan pramusaji dan fasilitas secara bersama-sama memiliki efek positif dan signifikan terhadap kepuasan pelanggan. Kualitas pelayanan pramusaji (X1) dan fasilitas (X2) dapat bertanggung jawab atas sekitar 56,2% variasi dalam kepuasan pelanggan, menurut koefisien persegi adjustable R (adj. R2) sebesar 0,562. Komponen tambahan yang tidak dimasukkan dalam model penelitian ini menyumbang 43,8% dari total variasi.
 
Ubud's Adiwana Arya Villa features a Wayang Restaurant. To ensure service quality and the restaurant's existence, the F&B service section always performs briefings before carrying out their separate work responsibilities. The goal of this study is to determine if the quality of waiter service and the amenities offered impact the degree of customer satisfaction at Wayang Restaurant in Adiwana Arya Villa. This study was carried out utilizing a quantitative descriptive approach using statistics. Data was gathered by having 99 individuals who ate at Wayang Restaurant Adiwana Arya Villa fill out questionnaires. Multiple linear regression is used to analyze data. According to the study's findings, the waitress's service quality has a significant impact on client satisfaction. This is demonstrated by the t-count value of 2.134, which is bigger than the t-table value of 1.985. As a result, the second hypothesis (H2) is invalid. Overall, it is possible to infer that in this study model, waiter service quality and facility quality have a favorable and substantial influence on customer satisfaction. According to the adjustable square coefficient R (adj. R2) of 0.562, waiter service quality (X1) and amenities (X2) may account for approximately 56.2% of the variance in customer satisfaction. Other variables not included in this study accounted for 43.8% of the overall variance.
Assessment of the disturbance of peat bogs of the Mogilev region
Authors: Ratnikova Olga N. , Navosha Yulian Yu. , Ageichik Inna V.
Published: January 2024

The analysis of high- and ultra-high-resolution satellite images of 1,385 peat bogs (with an area of more than 10 hectares) located on the territory of the Mogilev region of the Republic of Belarus showed that about 37 % of the total area of 221 thousand hectares of peat bogs were preserved in their natural state, the rest was subjected to hydraulic reclamation. The share of drained lands with peat soils of agricultural use was about 30 %, covered with forest vegetation - about 7 %, disturbed swamps - 26 %.
Assessing corporate social responsibility and poverty reduction programmes in the emerging markets
Authors: Anam Bassey Ekpenyong , Ironbar Virginia Emmanuel , Ijim Uno Agbor , Abang Pius Otu , Duke Otu Offiong , Ojong Felix Eja , Eba Maxwell-Borjor Achuk , Uzoh Esther Esien-Cobham , Okorn Felix Tabi , Bisong Bisong Daniel
Published: January 2024

According to Frynas et al. (2000), poverty is a global challenge which has attracted the concerns of the government and non-government organisations. The paper aims to examine corporate social responsibility (CSR) and poverty reduction programmes in the emerging market. The scope of the paper is limited to the activities of Lafarge Africa Plc in Cross River State. It adopts a survey research method. Data was obtained through unstructured interviews and questionnaires, administered to a sample of 400 respondents: staff of the company and resident in Mfamosing village, in Akamkpa Local Government Area. Data obtained were analysed using independent t-test analysis to test the hypotheses. The main findings of that study show that the provision of educational support programmes by Lafarge Africa Plc significantly contributes to poverty reduction in Cross River State, also that the maintenance of rural roads by Lafarge Africa Plc significantly contributes to poverty reduction in Cross River State. The study concludes and recommends the need for inclusiveness and community participation, in the initiation, design, and implementation of CSR in Cross River State and developing economies at large.
Radiative Heating of High-Level Clouds and its Impacts on Climate
Authors: Haslehner Kerstin , Gasparini Blaz , Voigt Aiko
Published: January 2024

The interactions of clouds with radiation influence climate. Many of
these impacts appear to be related to the radiative heating and cooling
from high-level clouds in the upper troposphere, but few studies have
explicitly tested this. Here, we use simulations with the ICON-ESM
global atmosphere model to understand how high-level clouds through
their radiative heating and cooling of the atmosphere, influence the
large-scale atmospheric circulation and precipitation in the present-day
climate. We introduce a new method to diagnose the radiative heating of
high-level clouds: we use a temperature threshold of -35°C to define
high-level clouds and also include the lower parts of these clouds at
warmer temperatures. The inclusion of the lower cloud parts circumvents
the creation of artificial cloud boundaries and strong artificial
radiative heating at the temperature threshold. To isolate the impact of
high-level clouds, we analyze simulations with active cloud-radiative
heating, with the radiative heating from high-level clouds set to zero,
and with the radiative heating from all clouds set to zero. We show that
the radiative interactions of high-level clouds warm the troposphere and
strengthen the eddy-driven jet streams, but have no impact on the
strength of the Hadley circulation and the latitude of the Intertropical
Convergence Zone. Consistent with their positive radiative heating and
energetic arguments, high-level clouds reduce precipitation throughout
the tropics and lower midlatitudes. Overall, our results confirm that
the radiative interactions of high-level clouds have important impacts
on climate and highlight the need for better representing their
radiative interactions in models.
Marine Strontium Isotope Evolution at the Triassic-Jurassic Transition Links Transient Changes in Continental Weathering to Volcanism of the Central Atlantic Magmatic Province
Authors: Heszler Bernát , Katchinoff Joachim A. R. , Palcsu Laszlo , Horváth Anikó , Vallner Zsolt , Kovács Emma Blanka , Planavsky Noah , Pálfy József
Published: January 2024

The end-Triassic extinction (ETE) is one of the most severe biotic
crises in the Phanerozoic. This event was synchronous with volcanism of
the Central Atlantic Magmatic Province (CAMP), the ultimate cause of the
extinction and related environmental perturbations. However, the
continental weathering response to CAMP-induced warming remains poorly
constrained. Strontium isotope stratigraphy is a powerful correlation
tool that can also provide insights into the changes in weathering
regime but the scarcity of 87Sr/86Sr data across the Triassic-Jurassic
boundary (TJB) compromised the use of this method. Here we present new
high-resolution 87Sr/86Sr data from bulk carbonates in Csővár, a
continuous marine section that spans 2.5 Myrs across the TJB. We
document a continuing decrease in 87Sr/86Sr the from the late Rhaetian
to the ETE, terminated by a 300 kyr interval of no trend and followed by
a transient increase in the early Hettangian that levels off. We suggest
that the first in the series of perturbations is linked to the influx of
non-radiogenic Sr from the weathering of freshly erupted CAMP basalts,
leading to a delay in the radiogenic continental weathering response.
The subsequent rise in 87Sr/86Sr after the TJB is explained by
intensified continental crustal weathering from elevated CO2 levels and
reduced mantle-derived Sr flux. Using Sr flux modeling, we also find
support for such multiphase, prolonged continental weathering scenario.
Aggregating the new dataset with published records employing an
astrochronological age model results in a highly resolved Sr isotope
reference curve for an 8.5 Myr interval around the TJB.
Workability and compressive strength of concrete containing binary cement, mixed fines, and superplasticizer
Authors: Oni Oluwaseun , Arum Chinwuba
Published: January 2024

Growing awareness about the influence of buildings on the environment has
resulted in a need for more ecologically friendly buildings made of
inexpensive but longlasting construction materials. Experimental findings on
the workability and strength qualities of concrete produced by partial
substitution of sand with lateritic soil at various percentage replacement
levels of cement with Rice Husk Ash (RHA) up to 15% are presented herein.
The chemical analysis of RHA and lateritic soil, as well as the consistency
and setting times of OPC and OPC/RHA pastes were conducted. They were all
found to be within the limits specified by appropriate standards. Slump
values for all concrete mixtures reduced with increase in the replacement
level of cement with rice husk ash (RHA), with and without the inclusion of
superplasticizer. However, for mixtures without superplasticizer, up till
10% replacement of cement with RHA, slump increased with increase in sand
replacement with laterite up to 20% and started fluctuating for laterite
levels beyond 20%. For mixes with superplasticizer, slump rose for laterite
levels up to 10% and fluctuation set in thereafter. The results also
revealed that at all ages and for all investigated levels of sand
replacement with laterite, the compressive strength of concrete attained its
highest value at 95% OPC with 5% RHA. Furthermore, this highest value of the
compressive strength is substantially the same with that of the 0%RHA with
0%laterite reference concrete. The findings of this research will be of
benefit to concrete professionals interested in the inclusion of laterite
and RHA to achieve greenness, sustainability, and cost-effectiveness in
concrete.
Effects of different spatial and precipitation input data on swat-derived catchment features
Authors: Zdero Senka , Srdjevic Zorica , Benka Pavel
Published: January 2024

Computer-based mathematical models are used in water management research to
represent ecological problems, simulate different processes, deal with such
problems and support their solution. Such studies require an
interdisciplinary approach that is both user-friendly and comprehensive to
integrate all of the processes that occur in nature. The use of available
hydrological models requires a model setup with a reasonable level of data
quality and quantity to represent catchment features to emphasize the
distinctive local character of ecosystems. One of the models that comply
with such requirements is the Soil and Water Assessment Tool (SWAT). This
paper aims to address the possible impact of different spatial and
precipitation input data on the catchment features by using SWAT for the
case study of the floodplain located within the Danube River Basin in
Serbia. The objective was to evaluate the impact of digital elevation
models, land use, and soil types with different resolutions (1) SRTM and
ASTER (30 m), TanDEM-X (12.5 m), (2) CORINE and GlobCover land use
databases, and (3) FAO/UNESCO world soil map and digitized soil map of
Vojvodina Province on catchment delineation. The research was conducted
alongside the analysis of precipitation, using data from the CFSR,
CarpatClim, and the national yearbooks. Regarding the spatial data, the
results indicate that the high-resolution data need to be adjusted for this
area, while the ASTER layer is suitable at an acceptable level for further
modeling in SWAT. Interpolated precipitation data are better to use due to
their higher resolution (10km) and the heterogeneous distribution of rain
gauge stations.
Investigation of the nitrogen and phosphorus content in arable agricultural land in Serbia
Authors: Simic Divna , Jankovic Snezana , Popovic Vera , Ikanovic Jela , Stankovic Sladjan , Rakic Sveto , Stevanovic Petar
Published: January 2024

The aim of this work was to determine the nitrogen and phosphorus content in
arable agricultural land on farms in the Republic of Serbia. The sampling of
soils was carried out in 2020 with the recording of GPS coordinates and
entering the obtained results into the software platform. The analysis of
the nitrogen content (N) was determined by the Kotzman method and calculated
from the humus on a sample of 30,957 plots, with an area of 19,629.24 ha.
The phosphorus content (P2O5) was determined by extraction, whereby the
easily soluble part of the phosphorus was transferred into a solution and
colorimetrically determined in the resulting extract, on a sample of 28,944
plots with an area of 18,459.96 ha. The results obtained show that 64.59% of
the area, i.e., 12,678.81 ha, had a good nitrogen content (0.2-0.1%). A very
high phosphorus content (400.1-500.0 mg kg-1 of the area) was found on
27.68% of the area, which is 5,108.92 ha. On 15.34% of the plots where a
harmful value was found, additional analyses should be carried out to
determine the cause of such a high phosphorus content in the soil. Based on
data on the content of total nitrogen and readily available phosphorus in
the soil, the type and amount of fertilizer can be adequately selected,
which can lead to a reduction in ecosystem pollution. The results in this
study represent the basis for soil management, biodiversity protection and
optimal planning of cultivation of arable, vegetable and fruit crops. The
obtained results can help agricultural producers and other entities to
increase the competitiveness of their production.
Do Analysts and Investors Efficiently Respond to Managerial Linguistic Complexity during Conference Calls?
Authors: Bushee Brian J. , Huang Ying
Published: January 2024

This paper examines whether analysts and investors efficiently incorporate the informational signals from managerial linguistic complexity (e.g., Fog) into their forecasts and trading decisions. We predict that a manager’s Fog during a conference call provides a signal of their private information through their willingness to engage with analyst questions. We find that informative (obfuscatory) managerial Fog provides a positive (negative) signal of future earnings growth. We also find that analysts efficiently revise their forecasts to both positive and negative signals, whereas investors only correctly interpret obfuscation during the call; there is a delayed price reaction to informative Fog. However, when buy-side investors ask questions during a call, we find an efficient price reaction to informative Fog. Our findings highlight an important benefit of two-way interactive disclosures and underline the importance of active call participation for efficiently incorporating linguistic signals of managers’ private information.

Data Availability: Data are available from the public sources cited in the text.

JEL Classifications: D82; G14; G20; M41.
Dependence and Super-exploitation of Labor in Latin America
Authors: Sotelo Valencia Adrián
Published: January 2024

This essay aims to expose the theoretical perspective of the exploitation of work in Marx for you discuss a relationship with one of the most important theses of the Marxist theory of the TMD exposed by brazilian intellectual Ruy Mauro MarinI: the extension of the super-exploitation of work to advanced capitalism as a new form of the expanded reproduction of capital for to counteract the economic crisis of capitalism and the growing problems in the production of value and surplus value that press the fall of the average rate of profit in the system.
Brazilian Transvestites for the World A Brief Ethnographic Report in the Bois De Bologne in Paris
Authors: dos Anjos Neto João Dantas
Published: January 2024

Brazil is a hostile environment for Trans and transvestite women, lacking effective public policies and government data, while being characterized by physical and symbolic violence against this group. The research highlights that the numbers of reports do not truly reflect the extent of violence against transvestites in the country due to unreported cases, as well as murders not registered by government public security systems for transphobic reasons. In 2022, the National Association of Transvestites and Transsexuals - ANTRA recorded an increase in the number of murders of transvestites in Brazil, which reduced life expectancy to 35 years. Some transvestites seek a better life by migrating to Europe, here more specifically France. For the transvestites studied, in their imagination, it is a territory for the production of financial and symbolic capital, as well as a life with more possibilities for other relationships. In conclusion, the study emphasizes the marginalization and challenges faced by trans and transvestite women in Brazil and France, highlighting prostitution as a survival strategy due to the lack of effective policies, with the possibility of finding and building other landscapes that keep them linked to life.
Genomic Activities of Mixed Lineage Leukemia Proteins
Authors: Dogan Senol
Published: January 2024

MLL is one of the most aggressive leukemias which mostly targets pediatric patients. Genetic rearrangement of the 11q23 location is the main reason for this type of acute leukemia. MLL gene and its fusion proteins have produced a core complex which leads to abnormal hematopoesis. Although many clinical and lab studies have been done to show the prominent role of MLL in leukemogenesis since its discovery in 1992, large-scale genomic data seems to be the most effective way to analyse the hematologic malignancies extensively. Gene expression, methylation, mutation, RNA-seq, and SNP arrays have updated the understanding of the transformation oncohematologic disorder mechanism. As a result of the genomic data analysis, new biomarkers may have been detected as therapy target genes and used for personalized medicine. The genomics-bioinformatics studies and novel technical advances provide some precious knowledge to discover novel therapeutic strategies and better treatment outcomes in the future.
In Silico Analysis of ADME-T Properties of Amentoflavone
Authors: V Krishna
Published: January 2024

Bioflavonoid, amentoflavone proven strong pharmacological properties. Prediction of in silico ADME-T properties by using PreADMET program. The result showed that amentoflavonehas good bioactivity, flexibility andpermeabilitywhich indicates that amentoflavone has potential to act as good drug.
Albizia Lebbeck Stem Bark Aqueous Extract as Alternative to Antibiotic Feed Additives in Broiler Chicks Diets: Haematology, Serum Indices and Oxidative Status
Authors: John Alagbe
Published: January 2024

A total of Three hundred and seventy five (375) one day old (Ross 308) broiler chicks with mixed sex were used to examine the effects of Albizia lebbeck stem bark (ATSM) aqueous extract as alternative to antibiotic feed additives in broiler chick’s diets: haematology, serum biochemical indices and oxidative status. Birds were divided to five treatments with five replicates of fifteen (15) birds in a completely randomized design. Treatment 1 (basal diet + 0 % ATSM), treatment 2 (basal diet +1.2 grams Oxytetracycline per litre of water), treatment 3 (basal diet + 10 ml ATSM per liter of water), treatment 4 (basal diet + 20 ml ATSM per litre of water) and treatment 5 (basal diet + 30 ml ATSM per liter of water) and the trial lasted for 56 days. Results on some haematological parameters revealed that red blood cell (RBC), pack cell volume (PCV), haemoglobin (Hb), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), white blood cell (WBC) and its differentials were significantly ((P<0.05) different among the treatments. Total protein, glucose, urea, cholesterol, creatinine, aspartate aminotransaminase (AST) and alanine aminotransferase (ALT) were significantly ((P<0.05) affected by ATSM. Activities of superoxide dismutase (SDA), glutathione peroxidase (GPx), catalase (CAT) and malonyldialdehyde (MLA) were significantly influenced by ATSM (P<0.05). It was concluded that ATSM could be administered to broiler chicks at 30 ml/litre without any negative effect on the general performance of birds.
Non-Invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: Pitfalls of Cytological and Histopathologic Diagnosis
Authors: TMM Hassan
Published: January 2024

Classical papillary thyroid carcinoma (PTC) is the commonest primary thyroid neoplasm. Besides PTC, significant histological variants that differ from classical PTC in regard to the morphological, cytologic and histologic features are mentioned; among them is follicular variant papillary thyroid carcinoma (FVPTC). The update WHO classification and the update Bethesda system reclassified FVPTC introduced a new entity which is "non-invasive follicular thyroid neoplasm with papillary like nuclear features" (NIFTP) that is characterized by an indolent behavior with encapsulated noninvasive growth features. Recently this entity is considering one of an indeterminate cytological categories (category III-IV-V). Update studies are found a combination of triple diagnostic procedures included sonographical, cytologic and molecular investigations can be suspecting preoperative diagnosis. Methods: A total of 150 selected cases of solitary thyroid nodules (STNs) with preoperative FNAC have an indeterminate follicular patterned cytological lesions with their underlying thyroidectomies that were collected in a 5-year period included in this article. Results: Majority of our cases were females and suffering from neck swelling. Cytollogically all the enrolled cases were lying in the indeterminate categories and histologically they were encapsulated with variable sizes follicles, nuclear features, no vascular invasion, no psammoma bodies, no tumor necrosis or mitosis. Also, there is no any extra-thyroid invasion. Conclusion: The accurate diagnosis of this entity “”NIFTP” carries many congratulations in regard that is “not malignant” category among both update TBSRTC and the final histopathological examination of the excised thyroid tissue.
Ayurvedic Management of Ek-Kushtha (Psoriasis): Review Article
Authors: S Anirudha
Published: January 2024

Ek- Kustha is a kind of Kshudra Kushtha that resembles psoriasis in its clinical presentations and is primarily caused by an imbalance of the Vata and Kapha doshas. It bears a greater resemblance with Psoriasis, which is a long-lasting autoimmune and chronic inflammatory skin disorder clinically characterized by erythematous, sharply demarcated papules and rounded plaques, covered by silvery micaceous scale predominantly affecting the skin of elbows, knees, gluteal cleft, and scalp. Some people may have severe Psoriasis is involving their entire body. The quality of life of patient with Psoriasis is often diminished because of the appearance of skin. The mainstays of psoriasis treatment include immune system suppressing drugs like methotrexate, PUVA, vitamin D3 lotion, and steroid creams. Some contemporary therapeutic methods do have serious drawbacks, particularly when used for an extended period of time. These modern treatment modalities are not devoid from grave complications mainly in long term use. Owing to these reasons, there is a need for treatment having good efficacy and no toxicity profile. So this case study was conducted considering Psoriasis as Ek-kuhstha and Ayurvedic management was planned accordingly. Drastic results were witnessed by Shodhana (Vasantik Vaman & Shardik Virechana) and Shamana (Some internal herbo-mineral preparations, External oil application).
https://medwinpublishers.com/JONAM/water-as-discussed-by-charaka-the-father-of-indian-medicine.pdf
Authors: G Asuti
Published: January 2024

The present day life style and food habits have been changed so much so drastically that the younger generation are landing up in many major health issues including life style disorders. Poly cystic ovarian syndrome, further resulting into primary infertility is a major cause of concern in the reproductive age groups of the present day generation. The present case report is of an infertile married couple who had not been able to conceive even after 4 years of regular unprotected sexual life. The female partner was diagnosed with PCOS. The couple underwent conventional treatments of primary infertility but did not get any fruitful results. Eager to conceive, they approached us for Ayurvedic treatment. Based on the Ayurvedic diagnostic parameters, the case was diagnosed as primary infertility (Vandhyatva) associated with poly cystic ovarian morphology. Along with proper lifestyle and diet, the patient was given with Ayurvedic Shamanoushadhis for 6 months, after which she successfully conceived and delivered a healthy male baby.
An Update on the Clinical Significance of Macroprolactinemia in Infertile Patients Presenting with Hyperprolactinemia: A Mini Review
Authors: KK Kaur
Published: January 2024

Hyperprolactinemia is a frequent presentation in case of patients with infertility. As many as 15-20% of women having irregular cycles possess hyperprolactinemia. Repression of the hypothalamo-pituitary-ovarian(H-P-O)axis through hampering of liberation of pulsatile gonadotropin-releasing hormone in view of hyperprolactinemia is a frequent endocrine cause of infertility. Previously we had reviewed prolactinomas in infertility as well as how do we treat prolactinomas in infertility in 2003&2005& highlighted the structure of macroprolactin besides treatment aspect. 3 kinds of human Prolactin(Prl) are existent-namely monomeric Prl, dimeric Prl as well as macro-Prl. Macro-Prl alias big-big Prl possesses a molecular weight(MW) of >150 kDa in addition to is implicated for 5-10%of circulating Prl in healthy subjects. In case of major kind of circulating Prl is macro-Prl, a diagnosis of macroprolactinemia gets established of the patients having hyperprolactinemia 10- 46% possess macroprolactinemia. In view of the need of ruling out a pituitary prolactinoma on finding escalated quantities of Prl-routinely as reproductive endocrinology & Infertility specialists(REI) we have a tendency of getting an imaging either as a CTScan or magnetic resonance imaging(MRI) for the same. However with the major work of the group of Hattori N, in the last 2-3 decades it has been emphasized how we need to first confirm that we don’t have macro- Prl for avoidance of unindicated investigations in case of macroprolactinemia leading to escalated blood tests, imaging as well as dopamine agonists treatment which puts extra burden of cost& stress of a tumor on the patients in case of this benign disorder.
Synthesis, Anti-Inflammatory and Antimicrobial Evaluation of Novel 2-phenyl-3-((4-phenylthiazol-2-yl) amino)thiazolidin-4- One Derivatives
Authors: B Nehra
Published: January 2024

In order to explore the therapeutic potential of thiazolidinone based analogues, five novel 2-phenyl-3-((4-phenylthiazol-2-yl) amino)thiazolidin-4-one derivatives (7a-e) were synthesized using multistep synthetic methodology. Structural elucidation of all synthesized molecules was performed by using IR and 1H NMR spectral reports. All molecules were accessed for their anti-microbial potential against a panel of four bacterial strains and one fungal strain. Results of in vitro antimicrobial data revealed compounds 7c and 7d as most potent antibacterial agent towards E. coli, S. aureus and B. subtilis with MIC values of 6.25 µg/mL while Compounds 7a, 7b and 7e as most active antifungal agents against tested fungal species i.e., R. oryaze (MIC = 3.125 µg/mL). Further, in vitro anti-inflammatory potential was evaluated for synthesized molecules in which compound 7d have powerful anti-inflammatory profile with IC50 value of 1.27 µg/Ml.