bluuebunny/crossref_metadata_2025 huggingface dataset:
Roadmapping as a Driver for Knowledge Creation: A Proposal for Improving Sustainable Practices in the Coffee Supply Chain from Chiapas, Mexico, Using Emerging Technologies
Authors: Contreras-Medina David Israel , Contreras-Medina Luis Miguel , Pardo-Nuñez Joaliné , Olvera-Vargas Luis Alberto , Rodriguez-Peralta Carlos Mario
Published: July 2020

Technologies are essential for productive sectors to increase competitiveness and improve sustainable development. However, the technology benefits present a great delay in adoption in agricultural sectors, due to discrepancies between scientific research and local needs. This article presents a study for improving sustainability practices in the coffee supply chain, using emerging technologies, of two localities in the Frailesca region from Chiapas, Mexico, based on the current situation, expectations and actions expressed by 165 coffee producers and 12 representatives of two coffee producers’ organizations. Based on Mentzer theoretical support, the technology roadmaps, knowledge management and digital compass were used to draw coffee supply chain processes to identify concrete actions and explore technologies. The results show that the technological route must be focused on renewing and improving coffee quality, getting quality certifications and access to specialized markets. Digital quality management and advanced statistical process control seem to be the appropriate emerging technologies for enhancing the acquisition of resistant varieties, proper pest management, improvement in the collection of coffee beans, the right time and way to plant a coffee plant, soil analysis and for the management of weeds and water conservation and harvesting as sustainable practices in this region. In addition, statistical correlation showed that digital technologies can be better adopted, on average, by producers with 4–6 family members, aged between 40–44 years and without additional crops. The findings propose sustainable practices linked with emerging technologies, based on a technology roadmap and knowledge management methodologies for this region.
Assessing the Achievement of the SDG Targets for Health and Well-Being at EU Level by 2030
Authors: Ionescu George H. , Firoiu Daniela , Tănasie Anca , Sorin Tudor , Pîrvu Ramona , Manta Alina
Published: July 2020

In this period of extreme changes in our society, issues related to the health and well-being of citizens are considered essential for the future of a united and prosperous Europe. Achieving the Sustainable Development Goals (SDGs) at EU level by 2030 requires hard work done in a transformative way in order to implement a set of coherent, evidence-informed policies that address health, well-being and all their determinants throughout the course of life and across all sectors of government and society. The objective of this paper is to assess the stage of fulfillment of all SDG targets in relation to health and well-being at EU level, based on the current trend of each indicator, for each EU member country. Based on the Eurostat SDG data set for 2007–2018, the individual trends were forecast using the AAA (Holt-Winters) version of the exponential smoothing (ETS) algorithm. The research results are surprising, on the one hand showing the possibility that some targets will be reached, but also indicating that a large percentage of targets will not be reached if the current trend is continued, especially due to disruptive change generated by the current pandemic. There is a need to increase the involvement of all member states, but also ensure a deeper involvement at the level of EU institutions, to provide full support for meeting the targets proposed by the 2030 Agenda, ensuring prosperity and health for all European citizens, and becoming a model for all the states of the world.
Relational Authenticity and Reconstructed Heritage Space: A Balance of Heritage Preservation, Tourism, and Urban Renewal in Luoyang Silk Road Dingding Gate
Authors: Su Xiaoyan , Sigley Gary Gordon , Song Changqing
Published: July 2020

Authenticity is a controversial concept in heritage studies. This is particularly the case where the reconstruction of heritage spaces is carried out to facilitate multiple objectives, namely, preservation, tourism development and improving the quality of life of local residents. Based on a qualitative methodology with a case study approach, this paper uses participant observation, in-depth interviews and textual analysis to explore the varying perceptions of authenticity for a reconstructed heritage site from the point of view of heritage experts, tourists and local residents. We identify a form of ‘relational authenticity’. Using the Dingding Gate, part of the Luoyang World Heritage section of the Silk Road, this paper highlights the phenomenon of ‘reconstructed heritage space’ with the relational authenticity of different actors in the Chinese context. We argue that relational authenticity is embedded in the networks between people, place, and (re)materialized space, which is the assemblage of excavated original objects and reconstructed buildings and spaces. Relational authenticity is acquired through a rematerializing process engaged by actors, who focus on the material qualities, instead of material authenticity and originality, of the original excavated objects and later reconstructed space.
Retrofitting High-Rise Residential Building in Cold and Severe Cold Zones of China—A Deterministic Decision-Making Mechanism
Authors: He Qiong , Hossain Md. Uzzal , Ng S. Thomas , Augenbroe Godfried L.
Published: July 2020

This study aimed to develop a deterministic decision-making mechanism for finding the optimum set of retrofit solutions of existing high-rise residential buildings in two different climatic zones of China. The retrofit solutions were critically examined with different energy saving targets based on the local climatic conditions, building features, and retrofit costs in cold and severe cold zones comparatively. By making the extensive review and analyzing considerable statistics data and cost information, net present value (NPV) method was employed in the prototype building apartments to develop this deterministic model. The results demonstrated that the heating system is the most important factor in saving energy and obtaining the optimum revenue in these two regions. The highest optimal NPV can be obtained by achieving 60% energy saving in the cold zone, as energy saving is around 319 kWh/m2/year with the total retrofit costs of USD $3560, while it is 281 kWh/m2/year with the total retrofit costs of USD $3480 to achieve the 50% energy-saving target in the severe cold zone. Based on the analysis of energy savings and retrofit costs, the results can be effectively implemented for the purpose of creating sustainable retrofits in existing buildings, and the model can be adapted for selecting appropriate retrofit choices in other climatic zones.
Many Miles to Paris: A Sectoral Innovation System Analysis of the Transport Sector in Norway and Canada in Light of the Paris Agreement
Authors: Koasidis Konstantinos , Karamaneas Anastasios , Nikas Alexandros , Neofytou Hera , Hermansen Erlend A. T. , Vaillancourt Kathleen , Doukas Haris
Published: July 2020

Transport is associated with high amounts of energy consumed and greenhouse gases emitted. Most transport means operate using fossil fuels, creating the urgent need for a rapid transformation of the sector. In this research, we examine the transport systems of Norway and Canada, two countries with similar shares of greenhouse gas emissions from transport and powerful oil industries operating within their boundaries. Our socio-technical analysis, based on the Sectoral Innovation Systems approach, attempts to identify the elements enabling Norway to become one of the leaders in the diffusion of electric vehicles, as well as the differences pacing down progress in Canada. By utilising the System Failure framework to compare the two systems, bottlenecks hindering the decarbonisation of the two transport systems are identified. Results indicate that the effectiveness of Norway’s policy is exaggerated and has led to recent spillover effects towards green shipping. The activity of oil companies, regional and federal legislative disputes in Canada and the lack of sincere efforts from system actors to address challenges lead to non-drastic greenhouse gas emission reductions, despite significant policy efforts from both countries. Insights into the effectiveness of previously implemented policies and the evolution of the two sectoral systems can help draw lessons towards sustainable transport.
Transparency as a Key Element in Accountability in Non-Profit Organizations: A Systematic Literature Review
Authors: Ortega-Rodríguez Cristina , Licerán-Gutiérrez Ana , Moreno-Albarracín Antonio Luis
Published: July 2020

The purpose of this article is to present a framework to understand transparency in the third sector and then to explore the main research streams regarding the disclosure of information and accountability by conducting a systematic literature review on the antecedents and dimensions of the transparency of information disclosed by non-profit organizations (NPOs). The essential questions of this work are addressed from an international perspective. In particular, we explore three research questions: (1) why should NPOs disclose transparent information to stakeholders? (2) Why do not all NPOs disclose transparent information? (3) What means do NPOs use to disclose transparent information? Our results highlight the lack of transparency legislation in the third sector, leading NPOs to adopt the voluntary disclosure of information policies to improve the perceived credibility of these entities by their stakeholders. In conclusion, our study highlights the importance of developing a systematic body of knowledge regarding the situation of transparent, voluntary information disclosure in the sector. Moreover, the Sustainable Development Goals promulgated by the United Nations place a high value on transparency for the accountability of institutions. To achieve sustainable development, both peace and the governance of institutions are needed. Reducing corruption and promoting transparency are among the goals which should be reached to achieve social sustainability.
Key Challenges and Opportunities for Recycling Electric Vehicle Battery Materials
Authors: Beaudet Alexandre , Larouche François , Amouzegar Kamyab , Bouchard Patrick , Zaghib Karim
Published: July 2020

The development and deployment of cost-effective and energy-efficient solutions for recycling end-of-life electric vehicle batteries is becoming increasingly urgent. Based on the existing literature, as well as original data from research and ongoing pilot projects in Canada, this paper discusses the following: (i) key economic and environmental drivers for recycling electric vehicle (EV) batteries; (ii) technical and financial challenges to large-scale deployment of recycling initiatives; and (iii) the main recycling process options currently under consideration. A number of policies and strategies are suggested to overcome these challenges, such as increasing the funding for both incremental innovation and breakthroughs on recycling technology, funding for pilot projects (particularly those contributing to fostering collaboration along the entire recycling value chain), and market-pull measures to support the creation of a favorable economic and regulatory environment for large-scale EV battery recycling.
Collaboration Model for Service Clustering in Last-Mile Delivery
Authors: Ko Seung Yoon , Sari Ratna Permata , Makhmudov Muzaffar , Ko Chang Seong
Published: July 2020

As e-commerce is rapidly expanding, efficient and competitive product delivery system to the final customer is highly required. Recently, the emergence of a smart platform is leading the transformation of distribution, performance, and quality in express delivery services, especially in the last-mile delivery. The business to consumer (B2C) through smart platforms such as Amazon in America and Coupang in Korea utilizes the differentiated delivery rates to increase the market share. In contrast, the small and medium-sized express delivery companies with low market share are trying hard to expand their market share. In order to fulfill all customer needs, collaboration is needed. This study aims to construct a collaboration model to maximize the net profit by considering the market density of each company. A Baduk board game is used to derive the last-mile delivery time function of market density. All companies in collaboration have to specialize the delivery items into certain service clustering types, which consist of regular, big sized/weighted, and cold items. The multi-objective programming model is developed based on max-sum and max-min criteria. The Shapley value and nucleolus approaches are applied to find the profit allocation. Finally, the applicability of the proposed collaboration model is shown through a numerical example.
Surface Plasmon Resonance-Based Temperature Sensor with Outer Surface Metal Coating on Multi-Core Photonic Crystal Fibre
Authors: Osifeso Samuel , Chu Suoda , Prasad Ashwini , Nakkeeran K.
Published: July 2020

We report an innovative design of a multi-core photonic crystal fibre-based surface plasmon resonance temperature sensor using ethanol and benzene as temperature-sensitive materials with a segmented outer-surface metal coating scheme. A stable sensing performance for a detection range of 10–80 ∘ C was found while using ethanol as the temperature-sensitive material; while using benzene both blue and red frequency shifts were observed. The maximum temperature sensitivities obtained from this proposed temperature sensor were 360 pm/ ∘ C and 23.3 nm/ ∘ C with resolutions of 2.78 × 10 − 1 ∘ C and 4.29 × 10 − 3 ∘ C, respectively, when using ethanol or benzene as the sensing medium.
A Randomized Controlled Study to Evaluate the Safety and Reactogenicity of a Novel rVLP-Based Plant Virus Nanoparticle Adjuvant Combined with Seasonal Trivalent Influenza Vaccine Following Single Immunization in Healthy Adults 18–50 Years of Age
Authors: Langley Joanne , Pastural Elodie , Halperin Scott , McNeil Shelly , ElSherif May , MacKinnon-Cameron Donna , Ye Lingyun , Grange Cécile , Thibodeau Valérie , Cailhier Jean-François , Lapointe Rejean , McElhaney Janet , Martin Luis , Bolduc Marilène , Laliberté-Gagné Marie-Eve , Leclerc Denis , Savard Pierre
Published: July 2020

Inactivated influenza vaccines efficacy is variable and often poor. We conducted a phase 1 trial (NCT02188810), to assess the safety and immunogenicity of a novel nanoparticle Toll-like receptor 7/8 agonist adjuvant (Papaya Mosaic Virus) at different dose levels combined with trivalent influenza vaccine in healthy persons 18–50 years of age. Hemagglutination-inhibition assays, antibody to Influenza A virus nucleoprotein and peripheral blood mononuclear cells for measurement of interferon-gamma ELISPOT response to influenza antigens, Granzyme B and IFNγ:IL-10 ratio were measured. The most common adverse events were transient mild to severe injection site pain and no safety signals were observed. A dose-related adjuvant effect was observed. Geometric mean hemagglutination-inhibition titers increased at day 28 in most groups and waned over time, but fold-antibody responses were poor in all groups. Cell mediated immunity results were consistent with humoral responses. The Papaya Mosaic Virus adjuvant in doses of 30 to 240 µg combined with reduced influenza antigen content was safe with no signals up to 3 years after vaccination. A dose-related adjuvant effect was observed and immunogenicity results suggest that efficacy study should be conducted in influenza antigen-naïve participants.
IMVAMUNE® and ACAM2000® Provide Different Protection against Disease When Administered Postexposure in an Intranasal Monkeypox Challenge Prairie Dog Model
Authors: Keckler M. Shannon , Salzer Johanna S , Patel Nishi , Townsend Michael B , Nakazawa Yoshinori J , Doty Jeffrey B , Gallardo-Romero Nadia F , Satheshkumar Panayampalli S , Carroll Darin S , Karem Kevin L , Damon Inger K
Published: July 2020

The protection provided by smallpox vaccines when used after exposure to Orthopoxviruses is poorly understood. Postexposu re administration of 1st generation smallpox vaccines was effective during eradication. However, historical epidemiological reports and animal studies on postexposure vaccination are difficult to extrapolate to today’s populations, and 2nd and 3rd generation vaccines, developed after eradication, have not been widely tested in postexposure vaccination scenarios. In addition to concerns about preparedness for a potential malevolent reintroduction of variola virus, humans are becoming increasingly exposed to naturally occurring zoonotic orthopoxviruses and, following these exposures, disease severity is worse in individuals who never received smallpox vaccination. This study investigated whether postexposure vaccination of prairie dogs with 2nd and 3rd generation smallpox vaccines was protective against monkeypox disease in four exposure scenarios. We infected animals with monkeypox virus at doses of 104 pfu (2× LD50) or 106 pfu (170× LD50) and vaccinated the animals with IMVAMUNE® or ACAM2000® either 1 or 3 days after challenge. Our results indicated that postexposure vaccination protected the animals to some degree from the 2× LD50, but not the 170× LD5 challenge. In the 2× LD50 challenge, we also observed that administration of vaccine at 1 day was more effective than administration at 3 days postexposure for IMVAMUNE®, but ACAM2000® was similarly effective at either postexposure vaccination time-point. The effects of postexposure vaccination and correlations with survival of total and neutralizing antibody responses, protein targets, take formation, weight loss, rash burden, and viral DNA are also presented.
Pathomorphism of HIV-associated mental disorders
Authors: Novikov Vladimir , Khritinin Dmitry
Published: July 2020

The article considers HIV-associated mental disorders, biopsychosocial factors affecting their development and course. Positive intradynamic pathomorphism of organic mental disorders is revealed. It manifests itself in easier clinical dynamics of psychoorganic syndrome, slower deterioration and dominance of the asthenic version of psychoorganic syndrome.
Model of correlation between anticipatory consistency and intuitiveness in the development of neuroses
Authors: Granitsa Alexander
Published: July 2020

The aim of the study was to form the model of correlation between intuitiveness and anticipatory consistency in case of neurotic and somatoform disorders. The study included 197 patients with neurotic and somatoform disorders and 66 healthy people. We found a lower level of intuitiveness and anticipatory consistency in patients with neurotic disorders than in healthy people. Correlation and cluster analyses have shown that anticipatory inconsistency and a reduced intuitiveness play a significant role in the mechanisms of neurosis development. Intuitiveness in neurotic and somatoform disorders is the link between anticipatory consistency and psychological defense mechanisms in the general system of coping with stress.
Content of selenium in the serum of patients with autosomal dominant spinocerebellar ataxia in the Khabarovsk region
Authors: I Dmitriy , Proskokova Tatyana , Yakusheva Natalya , Kovalskiy Yuriy , Khelimskiy Aleksandr
Published: July 2020

In patients with autosomal dominant spinocerebellar ataxia (AD SCA), the level of selenium in the blood serum was lower by a factor of 1.6 than the result obtained in the control group. There is a weak correlation between the severity of ataxia and selenium content in the blood serum of patients with AD SCA, which possibly suggests the participation of selenium in the pathogenesis of the disease. Given the decrease in selenium content in blood serum in patients with AD SCA, it is probably advisable to include selenium preparations in the symptomatic therapy for these patients.
Clinical and psychological research of somatoform disorders
Authors: Mukhametova Alsu , Vasilyev Valeriy
Published: July 2020

The article presents the results of a clinical and psychological study of a group of inpatients with somatoform disorders. Characteristics of syndromes and nosology of mental disorders in the studied patients, analysis of the leading etiological factors of their diseases, and personal and psychological characteristics of the patients themselves are given. Some aspects of the pathogenesis of somatoform disorders, as well as issue of their nosology, are discussed.
Modern psychodynamic psychotherapy of somatoform disorders: technology, effectiveness
Authors: Belokrylov Igor , Semikov Semen
Published: July 2020

At the present stage psychodynamic (psychoanalytic) psychotherapy is one of the most commonly used methods of psychological treatment and somatoform disorders (SFR), second only to cognitive-behavioral psychotherapy. The trends of the method technology are the following: focusing interventions on the most important pathogenetic mechanisms of SFR, short-form preference, distant treatment via the Internet, combining the basic technique with nonanalytical methods (in particular, hypnosis). The studies highlighted in the review provide reliable information about the effectiveness of the psychodynamic psychotherapy of SFR, however currently the evidence database on this issue is not sufficient and needs to be replenished.
International Red Cross and Red Crescent
Authors: Makhnycheva Yu. , Gordienko Е.
Published: July 2020

The International Committee of the Red Cross (ICRC) is an international independent organization, staff of which provides humanitarian aid to affected and needy people. The ICRC works in armed conflict zones, in areas of natural disasters, natural and technogenic accidents. In peacetime, the organization’s employees fight against physical violence, provide assistance with water supply and improving housing conditions, visit prisoners, monitor the conditions of detention and respect for their rights in addition to large-scale rescue operations. The ICRC's work includes family reunification, humanitarian diplomacy, health care, mine action, economic security and much more. The movement includes the International Committee of the Red Cross, National Red Cross and Red Crescent Societies, and the International Federation of Red Cross and Red Crescent Societies. The management of the ICRC is represented by the Assembly, the Assembly Council, the Directorate. Peter Maurer, President of the ICRC, heads the Assembly Council and the Assembly of the International Committee of the Red Cross.
Peculiarities of assessing patients' ability to work after total knee replacement
Authors: Ruzibaev Dilmurod , Asilova Saodat , Minasov Timur
Published: July 2020

This work is based on a clinical and laboratory study of 87 patients and persons with disabilities who had knee arthroplasty surgery. The observation was carried out in the period after the operation from 6 months to 5 years from 2014 to 2019 in the clinic of the National Center for Rehabilitation and Prosthetics of Disabled. The results of a comprehensive study included: clinical (orthopedic, neurological), psychological, radiological, biomechanical, physiological examinations (electromyography, electrocardiography, dynamometry, physical, neuropsychiatric condition and change in working positions). Clear indicators have been developed for assessing the function of the limb after surgery, as well as the duration of recovery after surgery, and influence of the recovery of the function on the static and dynamic function has been studied.
Providing aid during epileptic seizure
Authors: Karepetyan Ashot
Published: July 2020

Epilepsy is a fairly common disease of the central nervous system, and it quite often appears in medical practice. The basis of this disease is the increased excitability of certain parts of the brain that occurs as a result of injuries, strokes, neoplasms, and some hereditary diseases. In the normal state, transmission between neurons is carried out using pulses, and in the case of a lesion, it can be a source of additional neuropulses, which leads to discoordinated excitation of the involved brain structures.
Role of thrombolytic therapy in the modern treatment plan for coronary artery disease and acute coronary artery occlusion
Authors: Sakhno Nataliya
Published: July 2020

The thrombosis mechanism is a coordinated process under the control of neurohumoral regulation and influenced by various factors. Any violation in the regulation system, activation of some factors and inhibition of others can lead to disorders in the coagulation system, affecting both the plasma and platelet hemostasis. Activation of platelet coagulation factors against the background of vascular sclerosis leads to the formation of blood clots, which clog the lumen of the coronary vessels and can lead to acute myocardial infarction. It was established that thrombosis is the cause of not only acute conditions, but also the progression of the disease. The main task in this case is the restoration of blood flow in the coronary vessels that provide myocardial nutrition. Therefore, correctly selected antithrombotic agents can take rightful place in the treatment and prevention of cardiovascular pathology, which is based on ischemic thrombosis.
Specifics of the diagnosis and treatment of diabetic cardiomyopathy
Authors: Skvortsov Vsevolod , Borisova Anzhela
Published: July 2020

A complex of pathological changes in heart that are caused by metabolic, vascular and electrolyte disorders during diabetes mellitus is called diabetic cardiomyopathy. The clinical pictures of this condition can be diverse — from an asymptomatic course to severe heart failure with shortness of breath, edema, cardialgia, acrocyanosis.
Knowledge of some aspects of the influence of antiepileptic drugs in patients with epilepsy
Authors: Bortyash Marina , Khanieva Marina
Published: July 2020

Substantial intensity of side effects and low tolerance of drugs are reflected directly on the quality of patients' lives. In common with positive therapeutic results, antiepileptic drugs have a toxic impact on an organism of human including drug dependency and they can lead to fatality in different conditions (in case of overdose, drugs abuse, heightened sensitivity of organism).
X-ray-anatomical and functional results of Bosch-Magnan osteotomy
Authors: Khairutdinov Ruslan , Minasov Timur , Yakupova Ekaterina
Published: July 2020

Up to a third of all patients with such medical condition as Hallux valgus can be not pleased with the outcome of an operation. It emphasizes the importance of the choice of specific osteotomy for each individual case. Minimally invasive surgery is used more often and to correct the valgus deformity of the first ray of the foot. Despite the growing interest in minimally invasive procedures, there are a few publications on percutaneous osteotomies. The purpose of this research is to identify and evaluate the available data on the results of treatment of patients with valgus deformity of the first toe using the Bosch-Magnan method.
Certification of Medical Workers to Confer Qualification Category: Current Issues (confined to the decade of the multifunctional expert group of the Departmental Certification Commission of the FMBA of Russia)
Authors: Abaeva Olga
Published: July 2020

The article is a review of the history of formation of the modern system of certification commissions in healthcare, as bodies carrying out a business assessment of industry personnel, their working principles, issues and problems of the regulatory framework.
Discipline of System Thinking in the Mental Culture of Medical Management
Authors: Berdutin Vitaliy
Published: July 2020

The increased level of information and psychological pressure recently has greatly influenced the mental culture of medical management and has caused a need for coverage of issues related to the discipline of systemic thinking. It turned out that teaching a person to think in a disciplined and systematic way is very difficult. Cliched mental models impede the spread of innovative diagnostic and treatment technologies. The success of any medical organization is impossible without a mental culture based on the discipline of thinking of stakeholders. The use of socionic typology allows the systematic management of production activities, starting from the natural forms of thinking of their infotypes. At the center of the mental culture of medical management should be the idea of socionically verified systemic thinking, disciplining it on the basis of reflective mechanisms.
Sensorineural hearing loss as a problem of modern otolaryngology (review)
Authors: Zhuravlev Anton
Published: July 2020

The article presents an overview of factors that contribute to the development of sensorineural hearing loss, and approaches to solving this problem. Considering that we receive a significant part of information about the world through sound signals — and a healthy person is able to recognize over 400,000 different sounds —preservation and restoration of the patient’s hearing is of particular importance for maintaining social activity in modern, informational conditions of the society development.
Assessment of diets in preschool educational institutions in Moscow
Authors: Gromova S. , Drozhzhina N.
Published: July 2020

The article presents the results of analysis of data from open sources and literature on the assessment of diets in preschool educational institutions in Moscow. It was found that for the period 2010–2015 and as of 2019, the change in food standards did not lead to a significant change in the quality of food and the number of basic food components, since the decrease in the norms of individual products is compensated by an increase in the norms of other products and the introduction of new products. However, problems in the field of catering in the DOE exist and are related, among other things, to the poor quality of outsourcing services by suppliers of ready meals and food products.
Influence of tobacco Smoking on obstetric history of women during pregnancy
Authors: Dzyubaylo A. , Lotkov V.
Published: July 2020

The article presents the results of the relationship of Smoking in women with a history of obstetric (OAA). The study is based on the results of a survey of 107 smokers and 136 non-Smoking women observed in the antenatal clinic for pregnancy. The study found an increase in the number of miscarriages and abortions in Smoking women compared to non-smokers. Detection of Smoking women of fertile age when attached to outpatient clinics, active detection of Smoking pregnant women, as well as Smoking relatives in the family, carrying out measures to reduce Smoking significantly reduce the likelihood of having children with chronic pathology.
Subjective assessment of quality of drinking water consumed by the population of the Voronezh region
Authors: Mekhantiev Igor
Published: July 2020

The aim of the study was to study the opinion of the population about the quality of drinking water from various sources, including drinking water, packaged in containers, and its impact on health. For the organization of the questionnaire, a free Internet service Google-form (https://www.google.com/intl/en/forms/about/), of Google, was used. The questionnaire included 20 questions. The survey was conducted by 1,158 residents of the Voronezh region, with a total population of 2,323 million people, which ensured representativeness of the results obtained with a given error of results of ± 5 %. It was found that the majority of respondents (30.7 %) prefer to use water from the centralized water supply system, purifying it in filter jugs. Bottled (packaged) drinking water is consumed by 17.1 % of respondents, while the population of the older age group uses it very rarely (5.9 % or 12 out of 203 people), preferring to use water from a centralized drinking water supply without purification with boiling (40.9 % or 83 out of 203 people), while the shares of a relatively young population in the age groups under 18 years old and 18–30 years old prefer to use bottled drinking water (71.4 and 26.5 %, respectively). Assessment of respondents’ opinions on the quality of drinking water consumed showed that 33.7 % of respondents were fully satisfied, 0.3 % satisfied, 49.2 % partially satisfied, and 16.8 % not satisfied. The respondents most often indicated the presence of scale, a color change, which is generally consistent with the data of objective laboratory control (increased stiffness, high iron concentration). The majority of respondents (74.3 %) do not note the effect of drinking water on their health, however, when taking water procedures, dryness and peeling of the skin were noted after taking a shower or bath — 25.4 % of those questioned, a combination of the negative effects of «dryness and peeling of the skin»+«hair hardness after washing» — 17.8 % of respondents. The identification of the share of the population consuming bottled (packaged) drinking water, as well as the determination of the proportion of the population using individual filters when drinking drinking water from the centralized water supply system, makes it possible to make corrections to the results of estimating the population exposed to an unacceptable level of risk associated with the unsatisfactory quality of drinking water from centralized water supply systems.
Epidemiological trends in morbidity and issues of rotavirus vaccine prevention at the present stage
Authors: Kaira A. , Faizuloev E. , Lavrov V. , Svitich O. , Solomay T. , Nikonova A. , Petrusha O.
Published: July 2020

The urgency of the problem of rotavirus infection is determined by the high incidence, complications, with the formation of chronic pathology and the possibility of fatal outcomes. The purpose of this work is to analyze the features of epidemiology of rotavirus infection in Russia. Materials and methods. A retrospective epidemiological analysis was carried out using official statistics. Results and discussion. The trend of a steady increase in incidence of rotavirus infection in Russia from 2001 to 2018 has been established. The territories with the highest incidence in Russia have been identified. Age groups with a high risk of rotavirus infection are children under 1 year and 1–2 year. The trends in the incidence of the disease in the age groups 3–6, 15–17, 18 years and older. Ongoing preventive measures do not have a significant impact on reducing the incidence of rotavirus infection. Circulating strains were established in territory of Russia. Conclusions. The analysis showed the high relevance of organization of rotavirus infection prevention system. The current restrictions on the coverage of rotavirus vaccination in Russian population do not allow effective control of epidemic process of this disease. therefore, it is extremely necessary to recommend the inclusion of rotavirus vaccination in the national calendar of preventive vaccinations of Russia. Most of antigenic G/P variants of rotaviruses circulating in Russia fully or partially correspond to composition of the Rota Tech vaccine, which makes it possible to predict high efficiency of its use in all the territories of our country.
Cytogenetic peculiarities of buccal epithelium in workers exposed to industrial aerosols
Authors: Sadrtdinova Guzyal , Masyagutova Lyalya , Shaykhlislamova Elmira , Zaydullin Iskander , Ivanova Rasima
Published: July 2020

The results of the studies on micronuclei and other cytogenetic anomalies in the oral mucosa cells in mining workers are presented. One hundred and thirty workers have been examined. The results obtained can be used to develop an algorithm for screening examinations of workers exposed to industrial aerosols to identify groups of increased cancer risk.
Differential diagnosis of dysphagia in the elderly
Authors: Gruzdev Oleg
Published: July 2020

Dysphagia is a disorder of the swallowing. The causes of dysphagia are inflammatory processes in the oral cavity, pharynx, esophagus, larynx, mediastinum, foreign bodies, cicatricial strictures and tumors, diffuse esophageal spasm, antipsychotic therapy, and some nervous diseases. It is manifested by difficulties or inability to swallow, pain during swallowing, food or liquid getting into the nose, larynx, trachea. Treatment for dysphagia consists in elimination of the underlying cause of dysphagia.
April 20 to 26, 2020 – World Immunization Week
Authors: Rybachok Oksana
Published: July 2020

Infectious diseases in the modern world continue to claim millions of human lives despite the achievements of medicine. While in developed countries the main cause of death is cancer and diseases of the cardiovascular system, it is the infectious processes that occupy leading positions in the structure of mortality in the third world countries. About 1.7 million children die from infections that could have been avoided by vaccination according to the World Health Organization. In contrast to the countries of Western Europe, where preventive vaccinations for the population are carried out for a fee, preventive vaccination in the Russian Federation is funded by the state. Immunoprophylaxis includes not only prevention of 12 major infections included in the calendar of preventive vaccinations (diphtheria, polio, tetanus, whooping cough, tuberculosis, measles, rubella, mumps, hepatitis B, pneumococcal infections and haemophilus influenzae, influenza), but also vaccination against 17 additional infections in case of epidemiological indications.
Use of kumis in people with risk of developing atherosclerosis
Authors: Gilmutdinova Lira , Kudayarova Rushaniya , Ivanov Aleksandr , Galimulina Elena
Published: July 2020

The results of the use of a natural therapeutic factor — koumiss from mare’s milk — in health programs for 78men with a risk of developing atherosclerosis are presented. It has been established that the course application of koumiss has hypolipidemic, anti-atherogenic effects, contributes to the inhibition of lipid peroxidation processes with an increase in the activity of antioxidant enzymes in individuals at risk of developing atherosclerosis.
New techniques of magnetic therapy in sanatorium and spa treatment of patients with focal pulmonary tuberculosis
Authors: Kaysinova Agnessa , Gerbekova Dinara , Morozova Tatyana , Gusova Berta
Published: July 2020

The research objective is to improve the efficiency of sanatorium and spa treatment of patients with focal pulmonary tuberculosis (FPT) in the phase of resorption and carnificaton with complex application of anti-tuberculosis drug chemotherapy, drinking mineral waters (DMW) and focused pulse magnetic therapy (FPMT). Materials and methods of the research. The study included 120 patients suffering from FPT with the first detected FPT in the phase of resorption and carnificaton without emission of Mycobacteria tuberculosis (MBT-), after a standard 2–3 month intensive chemotherapy in anti-tuberculous institutions in their place of residence. By random sampling, 3groups were formed: in the main group (MG; 42 people) the patients received complex sanatorium and spa treatment (SST), standard anti-tuberculous chemotherapy (isoniaside and pyrazinamide), DMW “Teberda”, FPMT; in the group of comparison (GC; 41people) the patients received standard SST and anti-tuberculous chemotherapy in combination with DMW Teberda; in the control group (CG; 37 people) the patients had only standard SST and anti-tuberculous chemotherapy. Results. Clinical effectiveness of complex SST with application of DMW and FPMT increases in comparison with application of only climatic- and anti-tuberculosis chemotherapy (CG) by 23.2% (p<0,05), and in the combination with drinking MW “Teberda” (GC) by 17.3% (p<0,05). Conclusion. The study proved synergistic positive effect of combined therapy (anti-tuberculosis chemotherapeutic agents, internal intake of medium-mineralized MW “Teberda”, FPMT) in FPT.
Modern methods of laser treatment for involutional changes in periorbital area and their justification
Authors: Haliullin Rustam
Published: July 2020

The article presents a detailed analysis of the mechanisms of involutive changes in the periorbital region, it considers the spectrum of possible aesthetic problems in this localization and methods for their prevention and correction, gives the anatomical structure of the periorbital region, describes the main types of lasers used in the periorbital region and their effectiveness, as well as protocols and complications.
Antinocyceptive effect of oxygen therapy and hirudotherapy in rehabilitation of patients with genital endometriosis
Authors: Uraeva Ya. , Ivanovа I. , Filatova E. , Lazarenko N.
Published: July 2020

The results of treatment of patients (n = 100) suff ering from genital endometriosis are presented. The 1-st (control, n = 30) group of patients, against the background of standard drug therapy, received the Elevit® complex; The 2nd (main, n = 70) group of patients additionally received oxygen therapy procedures, in the form of oxygen inhalations from the Newlife apparatus and hirudotherapy using medical leeches. The course of treatment consisted of 10–12 procedures. The severity of pelvic pain in these patients was assessed on the YOUR scale in the period: before and after treatment, as well as after 1, 3, 6, 9 months. As a result, in patients in the 2-nd (main) group receiving complex treatment, the pain syndrome signifi cantly decreased, and it was also possible to predict its further decrease by two periods ahead, according to statistical regression analysis, compared with the treatment results in patients in 1-th (control) group.
Robotic mechanotherapy in the prevention of contractures in patients after minimally invasive knee surgery
Authors: Yashkov Alexander , Polyakov Viktor , Shelykhmanova Marina , Ardatova Anastasiya , Kulagin Evgeniy , Boguslavsky Dmitry
Published: July 2020

The active introduction of minimally invasive operations into medical practice has caused the need to improve rehabilitation approaches. We observed patients aged 18–62 years in the early and late postoperative period after minimally invasive knee operations. In addition to traditional rehabilitation treatment, including therapeutic gymnastics, lower limb and lower back massage, and electrical stimulation of the quadriceps femoris, patients in the main group received robotic mechanotherapy. The eff ectiveness of treatment and rehabilitation measures was evaluated by clinical method, electrothermometry, using algofunctional indices (VAS) and the degree of disability (Leken scale). As a result of these measures, the increase in the bending angle in the main group averaged 38,7 ± 4,3° per course of treatment. The average number of robotic mechanotherapy procedures per treatment course was 7,9. In the comparison group, the increase in the bending angle was signifi cantly less (14,1 ± 0,5°) over 10 days of treatment and rehabilitation activities. Pain in the lower extremities at the end of the course of treatment signifi cantly decreased to 2,8 ± 0,09 in the comparison group and 1,8 ± 0,08 in the main group and was rated as mild pain. However, in the main group, its decline was signifi cantly lower. According to the Leken scale, as a result of 10-day course of treatment, patients in the comparison group maintained a moderate degree of disability (6,9 ± 1,7), and patients in the main group — light (4,5 ± 1,78). Analysis of electrothermometry results showed that robotic mechanical therapy procedures increase thermal radiation by an average of 0,6 ± 0,22 °C for 20 minutes of mechanical therapy on the fi rst day and by 1,1 ± 0,2 °C for 30 minutes on the last day. Thus, treatment and rehabilitation measures using robotic mechanotherapy have signifi cantly reduced the pain syndrome, reduced the degree of disability due to earlier normalization of the function of the operated joint, improved blood circulation and neuro-vascular regulation and, as a result, trophic and regenerative processes.
Combined minimally invasive surgical treatment of chronic internal hemorrhoids
Authors: Egupov S. , Rodoman G.
Published: July 2020

This article is devoted to the results of applying the original minimally invasive surgical technique for the treatment of chronic internal hemorrhoids. The purpose of the study is to improve the outcomes of treatment in patients with chronic internal hemorrhoids by the simultaneous use of pathogenically substantiated low-traumatic surgical methods: dearterialization of internal hemorrhoids with Doppler guidance and clamping with latex rings. Materials and methods. Study included 204 patients with chronic hemorrhoids of the II–III degree, divided into 3 groups depending on the technique of minimally invasive surgery. The standard research methods for coloproctology were used. Results. It was found that the best short-term and long-term results of the surgical treatment of chronic internal hemorrhoids were obtained using the combined surgical technique proposed by the authors. Conclusions. The proposed combination of minimally invasive surgery may be the method of choice in the surgical treatment of chronic hemorrhoids of the II–III degree.
Intelligence without Data
Authors: Sun Zhaohao , Huo Yanxia
Published: July 2020

This article explores intelligence without data. More specifically, it reveals what the study of big data ignores in the trinity age of big data, analytics, and intelligence, and looks at DIKEW intelligence through presenting an integrated framework of intelligence. It then examines intelligence without data and wisdom algebra. It demonstrates that intelligence without data consists of information intelligence without data, knowledge intelligence without data, experience without data, intelligence without data, and wisdom intelligence without data, based on the hierarchy of wisdom. It argues that big data must incorporate intelligence without data to serve the world. At the same time, intelligence without data could enhance human intelligence, cognitive intelligence, machine intelligence, and business intelligence.
Silencing and Silence: Language and Specialized Listening in a Long-Term Institution for the Elderly
Authors: Pelis Simone Maximo , Santos Sampaio Nirvana Ferraz
Published: July 2020

This article presents the result of research developed with the language of elderly residents at the Long Term Care Facility for the Elderly - ILPI, in Vitória da Conquista, Bahia, Brazil. In response to the initial questions as to whether institutionalization affects the language of the elderly, whether the re-signification of verbal by non-verbal speech occurs, and whether silence, as language is part of an alternative system of possible meaning for the elderly, it was perceived that language in institutionalized long-lived individuals it reveals that in response to diversified processes of silencing, they have instituted silence as a possibility of reframing, and structuring of meaning. We collected data through the filming and recording of the elderly in enunciative-discursive situations, considering the uniqueness of each subject's history and their respective crossings as well as the condition of production of the narratives based on the concept of data-finding by Maria HadlerCoudry (1), aligned with notions relevant to Linguistics in the theoretical-methodological perspective of Discursive Neurolinguistics.
Eminence Grise of the Genome: Long Non-Coding Ribonucleic Acids in oral Squamous Cell Carcinomas
Authors: Venugopal Dr. Reshma , Manoj Bavle Dr. Radhika , Muniswamappa Dr. Sudhakara , Makarla Dr. Soumya
Published: July 2020

Non-coding ribonucleic acids (ncRNAs) are a class of RNA molecules that are transcribed but not translated into proteins, but they affect various cellular processes. Around 60% of genes in humans do not code proteins but regulate target gene expression. Presently, a lot of research is carried out on ncRNA involvement in oral squamous cell carcinoma (OSCC) and its precursor lesions termed as oral potentially malignant disorders (OPMDs). They are broadly classified as small ncRNAs (sncRNA) and long ncRNAs (lncRNA). sncRNAs are extensively studied, whereas the divulgence of lncRNAs in OSCCs needs more revelation, hence reviewed in the present article. LncRNAs have a base pair length of more than 200, can form complex structures and influence the gene expression in a multifaceted pattern that attracts interest.