bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of Water Resources Availability in Amu Darya River Basin Using GRACE Data
Authors: Salehie Obaidullah , Ismail Tarmizi bin , Shahid Shamsuddin , Hamed Mohammed Magdy , Chinnasamy Pennan , Wang Xiaojun
Published: February 2022

Water is diminishing in many places of the globe due to human intervention and climate variability. This study was conducted to assess water sustainability in the Amu Darya basin, the largest river catchment of central Asia, using two Gravity Recovery and Climate Experiment (GRACE) satellite solutions with a spatial resolution of 0.5°. Spatial variability of water sustainability was estimated by integrating reliability, resiliency and vulnerability. In addition, the Modified Mann–Kendall (MMK) test was utilized to detect the significant trends in water availability. Findings show a significant decline in the basin’s water supply, especially after 2010. Water availability was more variable in the east and a small area in the south. Trend analysis revealed higher declination in water availability in the range of −0.04 to −0.08 cm/year in the tundra and warm dry continental climate zones and the delta region of the basin ending in the Aral Sea in the cold desert climate zone. Water resources in the cold semi-arid (steppe) and most parts of the cold desert climate are more sustainable than the rest of the basin. Overall, the results indicate that water resources availability in a large-scale basin with climate diversity could be well assessed using the method used in this study.
The Detection of SARS-CoV-2 in the Environment: Lessons from Wastewater
Authors: Santiago-Rodriguez Tasha Marie
Published: February 2022

Wastewater has historically been an important source of enteric pathogens, as well as a source of unconventational or unexpected pathogens, including those present in the respiratory tract, saliva, urine, and blood. This is the case with SARS-CoV-2, the causative agent of the most recent pandemic. SARS-CoV-2 has been identified in wastewater across various geographical regions prior to, and during, the report of cases. The detection of SARS-CoV-2 in wastewater is usually performed using molecular techniques targeting specific genomic regions. High-throughput sequencing techniques, both untargeted and targeted or amplicon-based, are also being applied in combination with molecular techniques for the detection of SARS-CoV-2 variants to determine the genetic diversity and phylogenetic relatedness. The identification of SARS-CoV-2 in wastewater has a number of epidemiological, biological, and ecological applications, which can be incorporated into future outbreaks, epidemics, or pandemics.
Research on Reservoir Optimal Operation Based on Long-Term and Mid-Long-Term Nested Models
Authors: Mo Chongxun , Zhao Shutan , Ruan Yuli , Liu Siyi , Lei Xingbi , Lai Shufeng , Sun Guikai , Xing Zhenxiang
Published: February 2022

In order to solve the problem that the existing optimal operation model of reservoirs cannot coordinate the contradiction between long-term and short-term benefits, the paper nested the long-term optimal operation and mid-long-term optimal operations of reservoirs and established the multi-objective optimal operation nested model of reservoirs. At the same time, based on this model, the optimal control mode is determined when there are errors in the predicted runoff. In the optimal scheduling nested model, the dynamic programming algorithm is used to determine the long-term optimal scheduling solution, and the genetic algorithm is used to solve the mid-long-term optimal scheduling. The optimal control mode is determined by three indicators: power generation benefit, water level over limit risk rate and the not-exploited water volume. The results show that, on the premise of meeting the flood control objectives, the nested model optimal dispatching plan has higher benefits than the long-term optimal dispatching plan and the actual dispatching plan, which verifies the superiority of the nested model in the reservoir optimal dispatching problem. When there is error in predicting runoff, among the water level control mode, flow control mode and output control mode, the average power generation benefit of output control mode is 150.05 GW·h, the low-risk rate of water level overrun is 0.29, and the not-exploited water volume is 39,270 m3. Compared with the water level control mode and the flow control mode, the output control mode has the advantages of higher power generation efficiency, lower water level over limit risk rate and less not-exploited water volume. Therefore, from the perspective of economic benefit and risk balance, the output control mode in the optimization scheduling nested mode is the optimal control mode.
Prediction of anti–inflammatory activity and target synthesis of benzothiazolylpyrazole derivatives
Authors:   Reshetnev Siberian State University of Science and Technology, Krasnoyarsk,, Bobrov Pavel Sergeevich , Anenko Denis Stanislavovich ,   PMFI — a branch of the Volgograd State Medical University of the Ministry of Health of the Russian Federation, Pyatigorsk, Kodonidi Ivan Panajotovich ,   PMFI — a branch of the Volgograd State Medical University of the Ministry of Health of the Russian Federation, Essentuki, Suboch Georgii Anatolievich ,   Reshetnev Siberian State University of Science and Technology, Krasnoyarsk
Published: February 2022

This work analyzes drug-likeness and predicts the pharmacokinetic properties of virtual structures of benzothiazolylpyrazole derivatives. Anti-inflammatory activity was predicted using the Molegro Virtual Docker 6.0.1 program. The condensation of benzothiazolyl-substituted 4-aminopyrazole with benzaldehyde, p-hydroxybenzaldehyde and benzoyl chloride has been described for the first time. As a result of targeted synthesis, a number of new benzothiazolylpyrazoles have been obtained. The structure of the products was confirmed by the data of IR spectroscopy.
Stability study of Celecoxib tablets 200 mg and Celecoxib sustained release tablets 200 mg by quality indicators during storage
Authors:   Peoples’ Friendship University of Russia, Ahmed Alkhodri Ahmed Alkhodri , Suslina Svetlana N. ,   Peoples’ Friendship University of Russia
Published: February 2022

Drafts of original documents have developed for tablets of the latest generation of non-steroidal anti-inflammatory drug celecoxib with traditional and modified release for the treatment of inflammatory diseases. To establish the shelf life of tablets, the assessment of stability by quality indicators during storage under accelerated conditions was carried out.
Promoting Women’s Health in the Menstrual Cycle Using Herbal Nanopharmacy
Authors:   RUDN University, Negin Mirzaee
Published: February 2022

Holistic medicine is a form of healing that considers the whole person-body, mind, spirit, and emotions in the quest for optimal health and wellness. Holistic Gynecology means a holistic outlook or approach to gynecological treatment and care, which means it utilizes the principles of holistic medicine. The specific events that occur during the menstrual cycle can be divided into four phases: The menses phase, The follicular phase, Ovulation, The luteal phase. Cycle syncing is when adapting the diet, exercise routine, social calendar, and even important work engagements to the different phases of the monthly menstrual cycle. Seed cycling is the rotation of different edible seeds into the diet at different times in the menstrual cycle. It is a practice believed to help regulate reproductive hormones. During the follicular phase, pumpkin seeds and flax seeds help improve estrogen levels while preventing excess estrogen. During the luteal phase, sesame seeds and sunflower seeds help boost progesterone production. According to some articles, it was extracted seeds oil (Flaxseeds, pumpkin seeds, Sunflower seeds, and Sesame) with the help of nanotechnology. Given the advances in nanotechnology oils, and essential materials of these grains can be extracted to improve their effectiveness in different phases of a menstrual cycle.
The use of low-temperature argon plasma and general magnetotherapy in the early postoperative period after surgical treatment of breast cancer
Authors:   FSBEI FPE RMACPE of the Ministry of Health of Russia, Gerasimenko Marina Yurievna , Evstigneeva Inna Sergeevna ,   FSBEI FPE RMACPE of the Ministry of Health of Russia, Kozyreva Valeriya Olegovna ,   FSBEI FPE RMACPE of the Ministry of Health of Russia
Published: February 2022

Taking into account the high prevalence of complications after radical surgical treatment of breast cancer, medical rehabilitation courses were developed and conducted in the early postoperative period (2–4 days after surgery) with the inclusion of physical factors: low-temperature argon plasma and general magnetotherapy, as well as physical therapy, biofeedback training on the support reaction (balance therapy) and individual classes with a medical psychologist. The study included 71 women who underwent surgery for breast cancer on 2–4 days after the surgery. The patients were divided into 2 groups, comparable in age, clinical and functional indicators, by simple randomization. At all stages of the study, the patients underwent clinical, functional and laboratory examinations, and questionnaires. In group1 (n = 36), 10 procedures of low-temperature argon plasma and general magnetotherapy were carried out in the early postoperative period against the background of standard therapy. In the 2nd group (n = 35,) the patients received low-temperature argon plasma. In addition to physiotherapy, all patients received a complex of physiotherapy exercises, balance therapy and classes from a medical psychologist. The results showed the disappearance of puffiness in the postoperative area and the upper limb, an increase in the volume and quality of movements, reduction in the manifestation of pain syndrome, as well as inflammation syndrome, acceleration of regeneration, prevention of the formation of rough scar tissue. The patients noted an improvement in general health, improved sleep. With further observation, the prolongation of the action of physical factors was noted. Thus, the combined effect of the studied factors makes it possible to prevent both early and late complications of the postoperative period and makes a positive effect on the restoration and maintenance of the quality of life, and the social adaptation of breast cancer patients.
A comparison analysis of perineal wound complication after abdominoperineal extirpation (literature review)
Authors:   SBHI City Clinical Hospital No. 24 of the Moscow Healthcare Department, Moscow, Musin Aleksey Ildarovich , Kornev Leonid Vladimirovich ,   SAEI HE N.I. Pirogov Russian National Research Medical University of the Ministry of Health of Russia,  SBHI City Clinical Hospital No. 24 of the Moscow Healthcare Department, Volenko Roman Aleksandrovich ,   SBHI City Clinical Hospital No. 24 of the Moscow Healthcare Department, Moscow, Shipovskaya Mariya Ivanovna ,   FSAEI HE N.I. Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Laberko Leonid Aleksandrovich ,   FSAEI HE N.I. Pirogov Russian National Research Medical University of the Ministry of Health of Russia, SBHI City Clinical Hospital No. 24 of the Moscow Healthcare Department
Published: February 2022

At the moment, there is no consensus on such important issues for the practicing physician as the choice of the type of abdominoperineal resection and the optimal way to close the perineal defect. The review presents the data on the incidence of perineal wound complications after the use of various types of rectal extirpation and various types of perineal defect closure. The inconsistency of the data makes it necessary to conduct further randomized studies.
Investigation of an alternative to direct anticoagulants in COVID-19 patients
Authors:   city clinical hospital № 24 Health Department of Moscow,  Pirogov Russian National Research Medical University, Rodoman Grigory Vladimirovich. , Shalaeva Tatyana Ilinichna ,   Pirogov Russian National Research Medical University, City clinical hospital № 24 of the Moscow healthcare department, Ivzhits Marina Aleksandrovna ,   Moscow Clinical Hospital 24, Moscow Healthcare Department, Zeynalova Svetlana Rustamovna ,   VDNH Reserve Hospital, City Clinical Hospital No. 24 of the Moscow Healthcare Department, Trubnikova Inessa Anatolievna ,   EANE Reserve Hospital, city clinical hospital № 24 Health Department of Moscow, Popova Ekaterina Valerievna ,   VDNH Reserve Hospital, City Clinical Hospital No. 24 of the Moscow Healthcare Department, Makhmudova Firyuza Omarovna ,   Russian National Research Medical University
Published: February 2022

Currently, the use of anticoagulants is a mandatory component of the complex therapy of COVID-19. Regarding the choice of drugs and their dosages, there is no consensus yet. Increasing doses reduces the risk of thrombosis, but at the same time increases the risk of bleeding, which is a common event in severe COVID-19. This makes it relevant to study alternative options for thromboprophylaxis. The aim of this study was to compare the efficacy and safety of oral sulodexide and dabigatran etexilate in patients with COVID-19. Sulodexide demonstrated the same clinical efficacy as dabigatran in the treatment of patients with a degree of lung damage not higher than CT-2, while the relief of the initially existing coagulopathy occurred significantly faster, and there was no excessive increase in thrombin time, characteristic of dabigatran.
ANALISIS FAKTOR YANG MEMENGARUHI KEJADIAN HIPERTENSI PADA SUKU BATAK DI WILAYAH KERJA PUSKESMAS CIKAMPAK KABUPATEN LABUHAN BATU SELATAN
Authors: Harianja Berliana , P Nadapdap Thomson , Anto Anto
Published: February 2022

Hipertensi atau tekanan darah tinggi merupakan masalah yang ditemukan pada masyarakat baik di negara maju maupun berkembang termasuk Indonesia.. Adapun tujuan Analisis faktor yang memengaruhi Kejadian Hipertensi pada Suku Batak di Wilayah Kerja Puskesmas Cikampak Kabupaten Labuhan Selatan. Jenis penelitian ini merupakan survei analitik dengan rancangan cross sectional study. Penelitian dilakukan di Puskesmas Cikampak, Kabupaten Labuhan Batu Selatan. Populasi dalam penelitian ini yaitu rata-rata kunjungan pasien sebanyak 48 orang pada bulan Oktober-November 2019. Sampel diperoleh dengan menggunakan total sampling. Untuk menganalisis data tersebut digunakan uji regresi logistik.. Berdasarkan hasil penelitian diketahui bahwa kejadian hipertensi berhubungan dengan umur (p=0,033), pola makanan (p=0,017), konsumsi kopi (p=0,000). Berdasarkan hasil penelitian, dapat disimpulkan bahwa faktor-faktor yang berhubungan dengan kejadian hipertensi berhubungan dengan umur, pola makanan, konsumsi kopi. Sehingga adapun saran dalam penelitian ini diharapkan agar penderita hipertensi mengurangi konsumsi faktor-faktor yang berhubungan dengan kejadian hipertensi dan melakukan pemeriksaan rutin di Wilayah Kerja Puskesmas Cikampak Kabupaten Labuhan Selatan
Uma questão sobre etimologia [ao Professor Luciano Lourenço]
Authors: Bruck Ney , Martins Greice
Published: February 2022

Partimos do interesse do Professor Luciano Lourenço, sobre a questão da etimologia, para propor-lhe uma questão. Intencionamos suscitar a reflexão sobre o que a etimologia é capaz de dizer e ao mesmo tempo não dizer, sobre as certezas que dela se derivam, bem como sobre as incertezas que sobre ela pairam. Através desses deslocamentos, intencionamos adentrar o campo da dúvida, atitude indispensável para lidar com temas tão importantes e complexos. Questionar (bem como questionar-se) reporta, nesse escrito, sobre o fato de que o exercício intelectual exige coragem e desprendimento, elementos generosamente manifestos e latentes em toda a obra de nosso homenageado.
Impacto de agentes de distúrbio nos serviços dos ecossistemas em povoamentos de
pinheiro bravo na Serra da Lousã
Authors: Fidalgo Beatriz , Salas Raul
Published: February 2022

Os danos causados por distúrbios provocados por pragas e doenças ou fenómenos
climatéricos extremos, têm vindo a intensificar-se nas florestas de toda a Europa e
também em Portugal, fruto das alterações climáticas em curso e da gestão florestal
aplicada. Neste trabalho estuda-se o efeito destes distúrbios na estrutura e composição
de povoamentos de pinheiro bravo e estimam-se os impactos na produção de serviços de
produção lenhosa, captura de carbono e biodiversidade. Conclui-se que a ação continuada
dos distúrbios produz alterações estruturais nos povoamentos que conduzem a uma
diminuição importante na sua capacidade de fornecimento dos serviços dos ecossistemas
estudados e que indicam a necessidade de aplicar novos modelos de silvicultura na gestão
destes povoamentos.
Цифрова радіорелейна станція дециметрового діапазону “Дніпро”
Authors: ЗАДУНАЙ О.C. , ГУМЕНЮК В.І. , ПАЛАМАРЧУК А.А. , БУРАК В.Д. , СТЕФАНИШИН Я.І. , ТАРАН Б.Д. , СЛЮСАР В.І. , УШАКОВ В.Д.
Published: February 2022

Цифрова радіорелейна станція дециметрового діапазону “Дніпро”
Purpose, Subject, and Consumer Comment on "Perceived Burden Due to Registrations for Quality Monitoring and Improvement in Hospitals: A Mixed Methods Study"
Authors: Hysong Sylvia J. , O’Mahen Patrick , Profit Jochen , Petersen Laura A.
Published: February 2022

Zegers and colleagues’ study codifies the perceived burden of quality monitoring and improvement stemming from the work by clinicians of registering (documenting) quality information in the medical record. We agree with Zegers and colleagues’ recommendation that a smaller, more effective and curated set of measures is needed to reduce burden, confusion, and expense. We further note that focusing on validity of clinical evidence behind individual measures is critical, but insufficient. We therefore extend Zegers and colleagues’ work through a pragmatic, tripartite heuristic. To assess the value of and curate a targeted set of performance measures, we propose concentrating on the relationships among three factors: (1) The purpose of the performance measure, (2) the subject being evaluated, and (3) the consumer using information for decision-making. Our proposed tripartite framework lays the groundwork for executing the evidence-based recommendations proposed by Zegers et al, and provides a path forward for more effective healthcare performance-measurement systems.
Convergence on Coercion: Functional and Political Pressures as Drivers of Global Childhood Vaccine Mandates
Authors: Attwell Katie , Hannah Adam
Published: February 2022

Background: Vaccine hesitancy is a global problem with diverse local policy responses, from voluntaristic to coercive. Between 2015 and 2017, California, Australia, France, and Italy increased the coerciveness of their childhood vaccine regimes. Despite this apparent convergence, there is little evidence of imposition, policy learning, or diffusion – the drivers that are usually discussed in scholarly literature on policy convergence. The fact that the four governments were oriented across the political spectrum, with quite different political and institutional systems, further indicates an empirical puzzle. Methods: To better understand the drivers of enhanced vaccine mandates, a crucial issue during the coronavirus disease 2019 (COVID-19) global rollout, this article engages with four case studies assembled from qualitative analysis of semi-structured in-country interviews and document analysis between November 2018 and November 2020. Key informants had specific expert knowledge or played a role in the introduction or implementation of the new policies. Interview transcripts were coded inductively and deductively, augmented with extensive analysis of legal, policy, academic and media documents. Results: The case analysis identifies two key and interacting elements in government decisions to tighten vaccine mandates: functional and political pressures. Policy-makers in Italy and France were primarily driven by functional challenges, with their vaccination governance systems under threat from reduced population compliance. California and Australia did not face systemic threats to the functioning of their systems, but activists utilised local opportunities to heighten political pressure on decision makers. Conclusion: In four recent cases of high-income jurisdictions making childhood vaccination policies more coercive, vaccine hesitancy alone could not explain why the policies arose in these jurisdictions and not others, while path dependency alone could not explain why some jurisdictions with mandates made them more coercive. Explanation lies in restrictive mandates being attractive for governments, whether they face systemic functional problems in vaccine governance, or political pressures generated by media and activists. Mandates can be framed as targeting whole populations or localised groups of refusers, and implemented without onerous costs or policy complexity.
Improving District Hospital Surgical Capacity in Resource Limited Settings: Challenges and Lessons From South Africa Comment on "Improving Access to Surgery through Surgical Team Mentoring – Policy Lessons From Group Model Building with Local Stakeholders in Malawi"
Authors: Bust Lynn , Chu Kathryn
Published: February 2022

Strengthening surgical capacity of district hospitals (DHs) in low- and middle-income countries (LMICs) has been recognised globally as key to improving equitable access to surgical care. This commentary considers the benefits and challenges of surgical mentoring in South Africa and applies the lessons learned to other low-resource settings. Surgical team mentoring programmes require consideration of all stakeholders involved, with strong relationships between mentors and mentees, and the possible establishment of roaming district surgical teams. Other components of a surgical ecosystem must also be strengthened including defining a DH surgical package of care, ensuring strong referral systems through a hub and spoke model, and routine monitoring and evaluation. These recommendations have the potential to strengthen surgical capacity in DHs in low-resource settings which is critical to achieving health for all.
Trust, but Verify Comment on "‘Part of the Solution’: Food Corporation Strategies for Regulatory Capture and Legitimacy"
Authors: Allen Luke N.
Published: February 2022

According to Lacy-Nichols and Williams, the food industry is increasingly forestalling regulation with incremental concessions and co-option of policy-making discourses and processes; bolstering their legitimacy via partnerships with credible stakeholders; and disarming critics by amending their product portfolios whilst maintaining high sales volumes and profits. Their assessment raises a number of fundamental philosophical questions that we must address in order to form an appropriate public health response: is it appropriate to treat every act of corporate citizenship with cynicism? If voluntary action leads to better health outcomes, does it matter whether profits are preserved? How should we balance any short-term benefits from industry-led reforms against the longer-term risk stemming from corporate capture of policy-making networks? I argue for a nuanced approach, focused on carefully defined health outcomes; allowing corporations the benefit of the doubt, but implementing robust binding measures the moment voluntary actions fail to meet independently set objectives.
LANDSCAPE ORGANISATION OF A RECREATION CENTRE ON THE TERRITORY OF KALININ VILLAGE OKTYABRSKY DISTRICT, ROSTOV REGION
Authors: Ivanova I. , Baranova T.
Published: February 2022

The article provides design solutions for the improvement of the territory of the recreation centre on the Don River in the Kalinin farm of the Oktyabrsky district of the Rostov region. A variant of functional zoning and landscaping of the territory is proposed.
PECULIARITIES OF THE WATER REGIME OF THE GENUS ABIES IN THE CONDITIONS OF THE CCR
Authors: Popova Valentina , Popova Anna
Published: February 2022

We studied the water regime of some species of the genus Abies introduced in the Central Black Earth Region. It was found that all of them are characterized by rather high indicators of water balance, which allowed them to adapt to local conditions.
The specifics of the forest sector in sparsely wooded regions in the context of setting the task of state support for the current areas of its sustainable development
Authors: Avdeeva Irina , Avdeev M.
Published: February 2022

The work shows the place of sparsely wooded areas in the Russian economy. The historical aspect of the formation of modern problems of sparsely wooded regions is noted. A discussion of the specific features of the forest sector in sparsely wooded regions is carried out. The balance and complexity of the use of forest resources and the system of public ideas about the economic values of forests are interconnected. The opportunities created by the public form of ownership of forest lands are noted. A typical sparsely wooded region, the Kursk region, has been investigated. The key factors and problems existing in the field of interaction between government and business are formulated, and some tendencies are explicated that will need to be taken into account when developing directions for improving this interaction to ensure sustainable development of the forest sector of the Kursk region.
ECONOMIC JUSTIFICATION OF THE ORGANIZATION OF PRODUCTION OF POWER TRANSMISSION POLES FROM MODIFIED WOOD
Authors: Parinov D. , Medvedev Ilya , Shamaev Vladimir
Published: February 2022

The tasks of organizing the production of power transmission poles from modified wood are divided into short-term and long-term. Short-term tasks include: attracting investments to create production; designing and manufacturing of the industrial plant SPK-5M and testing the technology of mass production of pillars with a length of 10.7 m; increasing the volume of production of poles from modified wood; creating additional jobs. The long-term tasks include: the organization of the production of power transmission poles from modified low-value hardwood according to the original technology; the introduction of the developed technology for the production of poles at an existing wood processing enterprise; mastering the supply of poles to the foreign market.
Digital Certificate Authority with Blockchain Cybersecurity in Education
Authors: Maulani Giandari , Gunawan Gunawan , Leli Leli , Ayu Nabila Efa , Yestina Sari Windy
Published: February 2022

In the 21st century the development of internet technology has experienced explosive developments with complex threats in Higher Education. Cyber ​​security is a priority issue for all countries by using data and communication technology in various aspects of life. In order to advance and improve the digital economy in the implementation of a comfortable and reliable electronic system with methods of increasing competitiveness, cyber innovation also builds understanding and sensitivity to national security and resilience. Cybersecurity is constantly changing and learning providers often do not have the authority or facilities and capacity in various activities that connect students, in ensuring their knowledge and expertise. In carrying out the provision and validation of qualifications that are tried exclusively at the centralized management of learning institutions or employing institutions, these days have more ownership of learning experiences with results without risking safety, security and accessibility. This validation provision is not prolonged because learning is far more international than before and education continues to frequently use online platforms. Education providers offer degree internships that represent a new method of expertise and provide a route of advancement in increasing employability prospects. Blockchain is a digital and decentralized ledger, encompassing a set of interlocking technologies. Blockchain is designed to transform the centralized as well as validation model to a decentralized ledger from a secure database. These databases are shared, replicated, and synchronized for validation at universities, legal or regulatory agencies and industrial bodies across the internet.
Development Of Village Office Service Models To Community Based On Mobile Computing
Authors: Watini Sri , Nurhaeni Tuti , Meria Lista
Published: February 2022

The village as a centre for government services to the community at the grassroots level is the government's principal development priority. This research resulted in the development of an online public service administration system based on open source and utilising a cloud computing method for population administration, moving, business permits, building permits, and letter issuance with ease and efficiency. A literature review of cloud computing technology was conducted, followed by surveys and data collection of information technology infrastructure design that can be applied to online community services, analysis of survey data on real conditions in several community service centres, particularly villages in Kampar Regency, and finally the creation of online community service models from the village, such as f. Using cloud computing technologies and a modular and dynamic development design, the outcome is a web-based village community service administration application system. This application paradigm also incorporates the benefits of open-source patterned apps with flexible system designs for implementation and development, as well as mobile device support to increase community service quality. The web-based network structure allows for online communication not just between villages and communities, but also between villages and sub-districts, and can be accessed using mobile devices at any time and from any location. The application model's development is also based on functionalities of business processes and village administration processes found in Indonesian government legislation. Each model has been tried to be fitted to the community service system and is intended to be integrated to maximise efficiency.
Design and Build a Multimedia System for Indonesian Religious Activities Based on Android
Authors: Ruhiawati Irma Yunita , Candra Ariya Panndhitthana , Sari Siti Nurindah
Published: February 2022

The people of Indonesia have a wide range of traditions and customs, as well as religious activities. The public's interest in Indonesian religious activities has grown as a result of the diversity of religious activities carried out by Indonesians. Multimedia has an essential role in allowing individuals to obtain information fast, especially as technology advances. As a result, in order to obtain information centrally, the public must search for appropriate information, which takes time. In circumstances like these, the issue is creating and developing an android-based multimedia system application that may assist the public in learning about the Indonesian people's religious activities. This study intends to assist Indonesians in obtaining information on their religious activities, so that they may quickly obtain information and learn about and comprehend their religious activities. The Luther–Sutopo version of the Multimedia Development Life Cycle (MDLC) was utilised, including stages for idea, design, material gathering, assembly, testing, and dissemination. This study led to the development of an Android-based multimedia system for religious activities among Indonesians.
Arancel externo común y su influencia en el comercio internacional del Paraguay (2000-2019)
Authors: Salcedo Rodríguez Camila Belén , Cabral López María Antonela
Published: February 2022

A partir del año 1995, se implementó en el Mercado Común del Sur (Mercosur) el Arancel Externo Común (AEC), aunque el mismo se encuentra perforado por distintas excepciones. El objetivo de este trabajo es analizar la influencia del AEC en el comercio internacional del Paraguay durante el periodo 2000-2019. La metodología empleada contempla el diseño documental bibliográfico, de nivel descriptivo y el enfoque cuantitativo. Por esto, se recurrió al modelo gravitacional del comercio para el estudio propuesto. Entre los principales resultados de esta investigación pueden señalarse que Paraguay posee una economía abierta, con una balanza comercial superavitaria y que el Mercosur es el principal destino de las exportaciones paraguayas y uno de los principales proveedores de sus importaciones. Además, el modelo utilizado permite apreciar que el AEC podría tener una repercusión positiva en el comercio internacional de Paraguay para el periodo de estudio.
“Quedar en el limbo”:
Authors: Chaves Dulce Daniela , Sotera Lisandro
Published: February 2022

Entrevista a Andrea Ibacahe Corante.
La violencia institucional como problemática transversal:
Authors: Jaime Florencia , Lapunzina Julian , Montes Santiago Ezequiel , Mottura Nadina Fernanda
Published: February 2022

El artículo da cuenta de la experiencia del proyecto “Jóvenes de Humanidades por los Derechos Humanos”, presentado en 2020 ante el Ministerio de Igualdad, Género y Diversidad de la Provincia de Santa Fe (Argentina). Aborda la problemática social de la violencia institucional, que se ha convertido en un emergente escolar para quienes se desempeñan como docentes en los barrios de la ciudad de Rosario. La temática se aborda desde una perspectiva histórica, contextualizada, interseccional y situada. La singularidad del proyecto radica en la elaboración de material pedagógico audiovisual, que cuenta con la participación y reflexión de grandes referentes de los Derechos Humanos en nuestro país. A su vez, se complementa con actividades propuestas para desarrollar y trabajar dentro del espacio áulico, especialmente en el Ciclo Básico Orientado. El objetivo del proyecto es brindar a lxs docentes y a las instituciones educativas un conjunto de herramientas para abordar la problemática específica de la violencia institucional vinculada a los Derechos Humanos.
Pengaruh Penggunaan Media Chromebook Terhadap Motivasi Belajar Siswa
Authors: Supriyadi Agus , Muis Abdul , Hidayati Lolita
Published: February 2022

Seiring berjalannya teknologi yang terus berkembang, sekolah dianggap perlu untuk mengikuti perkembangan teknologi dalam hal sarana dan prasarana yang dipakai termasuk media pembelajaran. Dalam penelitian ini metode yang digunakan ialah jenis kuantitatif. Teknik analisis datanya ialah menggunakan analisis statistik deskriptif dan analilsis korelasi product moment. Untuk menguji hipotesis, menggunakan bantuan program SPSS versi 16.0. Sedangkan pengumpulan data, digunakan angket, observasi, wawancara, dan dokumentasi.. Setelah dilakukan penelitian, maka dapat disimpulkan bahwa penggunaan media pembelajaran chromebook bagi siswa termasuk kategori baik. Sedangkan untuk motivasi belajar siswa ketika menggunakan media pembelajaran chromebook, termasuk dalam kategori cukup. Sedangkan perhitungan pada tabel correlation pada SPSS dimana koefisien korelasi adalah 0,543 dengan signifikasi 0,000. Karena signifikasi <0,05, maka Ho ditolak berarti Ha diterima dan r hitung> r tabel 0,543 > 0,254. Kesimpulannya terdapat pengaruh yang sangat kuat penggunaan media pembelajaran chromebook terhadap motivasi siswa kelas VII di SMP Negeri 1 Asembagus
Influence of alcohol abuse on the structural and functional condition of the uterine tubes in women of reproductive age
Authors: Lytvynenko M.V.
Published: February 2022

Women's health is always the focus of physicians and society. Some physiological features of women's anatomy and physiology determine their specific response to chronic alcohol intoxication, which is better studied for the ovaries, uterus and mammary glands. The study was conducted to examine the effect of excessive long-term alcohol abuse by women of reproductive age on the structural and functional state of their fallopian tubes. The study was based on sectional material from 25 women with chronic alcohol intoxication, with alcoholic cirrhosis of the liver, but without other existing comorbidities. Possible destructive-sclerotic changes of the fallopian tubes were studied. It was found that in such women the ampullary section of the fallopian tube is significantly shorter by 7.55%. At the same time, there is also a decrease in the outer diameter in the area of the transition of the isthmus to the ampullary department by 17.62% and a narrowing of the lumen area of the ampullary department by 13.14%. Sclerotic-destructive changes were found in the epithelium and in the muscular layer of the fallopian tube. The relative amount of connective tissue in women of the study group was higher than in women in the control group by about 4 times. Immunohistochemical examination of samples of uterine tube section material was also performed, during which signs of stress adjustment of the fallopian tube under the influence of chronic alcohol intoxication and markers of apoptosis, increased p53 protein activity in the study group (this protein acts as a transcription factor and regulates cells). The study concluded that chronic alcoholism can certainly be a factor that causes a number of pronounced, profound, and sometimes irreversible changes in the structure of the fallopian tubes.

Keywords: chronic alcoholism, morphofunctional consequences of intoxication, morphometry, immunohistochemistry.
Hubungan Pengetahuan tentang Anemia dan Dukungan Keluarga terhadap Kepatuhan Konsumsi Tablet Tambah Darah pada Remaja Putri di SMPN 01 Brondong Lamongan
Authors: Ningtyas Octaviani , Ulfiana Elisa , Yono Ngadi
Published: February 2022

Anemia
Satu Bulan Penerapan Yoga Anak Meningkatkan Konsentrasi Belajar Usia Prasekolah
Authors: Sofiyanti Ida , Setyowati Heni
Published: February 2022

Based on Riskesdas 2018, 29.9% of Infants Under Two Years (Baduta) experienced very short and short nutrition. Still based on the results of the 2018 Riskesdas, there is a comparison of child development in children aged 36-59 months in Indonesia with a total development index of 88.3%, of which 64.6% is literate, 97.8% is physical, 69.9% is social-emotional, and 95. 2% learning. The ability and development of children need to be stimulated so that children can grow and develop optimally and according to their age. Stimulation is stimulation (sight, speech, hearing, touch) that comes from the child's environment. Children who get directed stimulation will develop faster than children who do not even get stimulation. Various efforts have been made to provide stimulation to children, one of which is by using Yoga activities. This study aims to determine the effect of yoga on children on learning concentration of preschool age children. The population and sample in this study were students in class A and class B with a total of 30 students, 15 students for the experimental group, and 15 students for the control group. This study uses a quasi-experimental research (Quasi Experimental) design used Non Equevalent Control Grub Design. The parametric hypothesis test used is the dependent t-test because the data is normally distributed. The test results stated that there were differences in the level of concentration in learning after being given yoga treatment for children for one monthAbstrak Berdasarkan Riskesdas 2018, 29,9 % Bayi Bawah Dua Tahun (Baduta) mengalami gizi sangat pendek dan pendek. Masih berdasarkan hasil Riskesdas 2018 didapatkan perbandingan perkembangan anak pada anak usia 36-59 bulan di Indonesia dengan total indeks perkembangan 88,3 %, dimana 64,6 % literasi, 97,8 % fisik, 69,9 % social emosional, dan 95,2 % learning. Kemampuan dan tumbuh kembang anak perlu diberikan stimulasi agar anak dapat tumbuh dan berkembang secara optimal dan sesuai umurnya. Stimulasi adalah perangsangan (penglihatan, bicara, pendengaran, perabaan) yang datang dari lingkungan anak. Anak yang mendapat stimulasi yang terarah akan lebih cepat berkembang dibandingkan anak yang kurang bahkan tidak mendapat stimulasi. Berbagai upaya yang dilakukan untuk memberikan stimulasi kepada anak salah satunya dengan mengunakan kegiatan Yoga. Penelitian ini bertujuan mengetahui pengaruh yoga pada anak terhadap konsentrasi belajar anak usia Prasekolah. Populasi dan Sampel dalam penelitian ini adalah Siswa kelas A dan Kelas B sejumlah 30 siswa dimana 15 siswa untuk kelompok eksperimen, dan 15 siswa untuk kelompok kontrol. Penelitian ini menggunakan penelitian eksperimen semu (Quasi Experimental) desain yang digunakan Non Equevalent Control Grub Design. Uji hipotesis parametrik yang digunakan adalah uji dependent t-test karena data berdistribusi normal. Hasil uji menyatakan ada perbedaan tingkat konsentrasi belajar setelah diberikan perlakuan yoga anak selama satu bulan.
A fenntarthatóság környezeti elemeinek megjelenése a hazai nagyvállalatok gyakorlatában
Authors: Kozma Dorottya Edina , Bosnyák-Simon Nikolett
Published: February 2022

Számos vállalat vezetőjére egyre nagyobb nyomás nehezedik, amiatt, hogy vállalatukat fenntarthatóvá tegyék. A fenntartható fejlődés, fenntarthatóság iránti érdeklődés növekedésével párhuzamosan nőtt a figyelem a fenntartható vállalatok iránt is. A vállalati fenntarthatóság gyökerei az érdekelt felek elméletében gyökereznek, melyben elismerik, hogy a szervezeteknek nem csak a részvényesek, hanem más érdekelt felek felé is vannak kötelezettségeik. Számos tényező készteti arra a vállalatokat, hogy a fenntartható fejlődés elveit átültessék a vállalati gyakorlatba. De valóban képesek ezt a gyakorlatban is megtenni? Ha igen, akkor hogyan? Milyen eszközök segítségével, milyen tevékenységek mentén teszik ezt? Kutatásunk során ezekre a kérdésekre kerestük a választ. Alapvető célunk annak vizsgálata és feltárása, hogy a hazai színtéren működő nagyvállalatok vállalati gyakorlatában a fenntartható fejlődés mely elemei, eszközei és milyen formában jelennek meg. A kutatási mintába a HVG által 2020-ban összeállított Top 500 listán szereplő nagyvállalatok kerültek be. Jelen tanulmányunkban az élelmiszer- és dohányipar, valamint a mezőgazdaság szektor vállalatait vizsgáltuk, ezek közül is 14 vállalat jelentését.
Egészségügyi innovációk Magyarországon – startup aspektus
Authors: Vitéz-Durgula Judit
Published: February 2022

A COVID-19 világjárvány okozta globális kihívás innovatív megoldásokra ösztönzi a világot. Csakúgy, mint más iparágakban, az egészségügy terén is megjelent az igény a digitális, a személyes kapcsolattól mentes tanácsadásra, a klasszikus orvos–páciens kapcsolattartás mellett. Ez a tendencia várhatóan hosszútávon meghatározza majd az egészségügy jövőjét. Az egészségügy terén létrejövő ötletek és kutatások száma a feltörekvő cégek számánál is nagyobb, azonban kevés vállalkozás van, ami hosszútávon képes eredményesen működni. Hazánkban több száz egészségügyi kutatás, valamint 100+ egészségügyi startup vállalkozás tűzte ki célul, hogy megoldást kínáljon a megváltozott helyzetre, hiányosságokra. Egy egészségügyi startup sikerét nem garantálja a vízió és az innovatív ötlet, legalább annyira fontos a megvalósításhoz az időzítés, a szakmaiság, a stabil pénzügyi és jogi háttér megteremtése és folyamatos biztosítása. Ebben a tanulmányban a Magyarországon útnak indult egészségügyi innovációkat térképezem fel. Bemutatásra kerülnek a következők: főbb jellemzők, scale-upok, finanszírozási lehetőségek, trendek – a fellelhető szekunder források tükrében.
Extractivismo, conflictos y ecocidio en África: el caso de la cuenca del río Congo (República Democrática del Congo) y del delta de Níger (Nigeria)
Authors:   Universidad Autónoma de Madrid, Kabunda Badi Mbuyi ,   Instituto Internacional de Derechos Humanos de Estrasburgo
Published: February 2022

Africa accounts for 33 percent of the planet’s natural resources: minerals, foodstuff s and energy sources. However, those resources do not contribute to an improvement in living conditions of Africans. Instead of a blessing, those resources have become a curse, as is the case of the Niger Delta. Africa also possesses significant forest resources. The jungles of the Congo River watershed make up the second-largest tropical biodiversity region after the Amazon. Unfortunately, the survival of these jungles has been threatened by the effects of mineral and agricultural exploitation, wars of depredation, and the activities of multinational logging companies. In contrast, protection efforts gain new territory with the creation of national parks and protected areas, the application of jungle management regulations and efforts of reforestation, and with greater adoption by mining and oil multinationals of their social and environmental responsibilities. The problem is structural and requires the adoption of another model of development, based on post-growth and eco-development, in place of the current ecocide.
El megaproyecto minero de Aznalcóllar: lodos, consenso y vuelta a empezar
Authors:   Universidad Pablo de Olavide, Zampier Maika , Talego Félix ,   Universidad de Sevilla
Published: February 2022

Se realiza la crónica de los hechos fundamentales del conflicto ambiental de la mina de Aznalcóllar (Andalucía, España), desde los años previos a la rotura de su balsa de lodos en 1998 hasta la actualidad. En esa fase, la Administración, con el acuerdo de todos los partidos políticos, apuesta por la reapertura de la mina. Ello supondrá que a las externalidades ya consumadas y los riesgos fatalmente cumplidos se sumen otros nuevos. Sólo una voz discordante, muy minoritaria, de las organizaciones ambientalistas se desmarca del consenso prominero. ¿Cómo explicar la extendida aceptación de la apuesta minera en un proyecto cuyos datos brutos lo sitúan entre los más riesgosos de los muchos previstos actualmente en España?
Rhythm and Movement Delivered by Teachers Supports Self-Regulation Skills of Preschool-Aged Children in Disadvantaged Communities: A clustered RCT
Authors: Williams Kate , Bentley Laura , Savage Sally , Eager Rebecca , Nielson Cathy
Published: February 2022

Self-regulation skills are an important predictor of school readiness and early school achievement. Research identifies that experiences of early stress in disadvantaged households can affect young children’s brain architecture, often manifested in poor self-regulatory functioning. While there are documented benefits of coordinated movement activities and music education to improve self-regulation, few interventions have focused exclusively on rhythmic movement activities within a universal preschool setting. This study investigated the effectiveness of a preschool intervention, delivered across eight weeks by generalist preschool teachers, which focused on coordinated rhythmic movement with music to improve self-regulation and executive function. The program is known as RAMSR (Rhythm and Movement for Self-Regulation). The study involved 213 children across eight preschools in disadvantaged communities. The intervention group received 16 to 20 sessions of a rhythm and movement program over eight weeks, while the control group undertook the usual preschool program. Primary outcome measures were executive function and self-regulation with secondary outcomes being school readiness and visual motor integration. Children across the study had baseline measures demonstrating substantial self-regulation and executive function challenges when compared to norms on these measures. Post intervention, significant intervention effects were found for self-regulation and importantly, fidelity and teacher report measures show that it is feasible for educators without any music background to deliver the program. These findings are important given that children from low socioeconomic backgrounds are both more likely to need support for self-regulation to support school transition and have inequitable access to quality music and movement programs. This study confirms that universal access to this beneficial approach can be created through building capacity in early childhood educators. This trial was registered pre-recruitment with the Australian New Zealand Clinical Trials Registry, ACTRN12619001342101.