bluuebunny/crossref_metadata_2025 huggingface dataset:
Toward Transparency: Implications and Future Directions of Artificial Intelligence Prediction Model Reporting in Healthcare (Preprint)
Authors: Turlip Ryan , Ozturk Ali K , Yoon Jang Won , Welch William C , Dagli Mert Marcel
Published: May 2024

UNSTRUCTURED

The rapid integration of Artificial Intelligence (AI) in healthcare emphasizes the transformative potential it holds for improving patient outcomes through data-driven decision-making. There is a drive toward implementing more complex predictive algorithms for disease diagnosis and prognosis. However, there are unique implications of AI that limit its clinical applicability and validity. To address these challenges, the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) group released an extension and update of its 2015 reporting guideline, the TRIPOD+AI, to enhance transparency and methodological rigor in regression and AI prediction model studies. The TRIPOD+AI framework encompasses an expanded scope, incorporating new domains such as fairness, open scientific practices, and patient and public engagement. It is anticipated that these augmented guidelines will facilitate the rigorous evaluation and subsequent adoption of artificial intelligence tools across diverse healthcare settings.
Long-Term Glycemic Control Improvement After the Home and Self-Care Program for Patients With Type 1 Diabetes: Real-World–Based Cohort Study (Preprint)
Authors: Koo Dae-Jeong , Moon Sun-Joon , Moon Suhyeon , Park Se Eun , Rhee Eun-Jung , Lee Won-Young , Park Cheol-Young
Published: May 2024

BACKGROUND

The prevalence of type 1 diabetes (T1D) is increasing worldwide, with a much higher proportion of adult patients. However, achieving stable glycemic control is difficult in these patients.

OBJECTIVE

After periodic implementation of structured education for patients with T1D through the Home and Self-Care Program, a pilot home health care project promoted by the Korean government, we evaluated the program’s effects on glycemic control.

METHODS

This study was conducted from April 2020 to March 2023. We analyzed 119 participants with T1D aged >15 years. Nursing and nutrition education were provided separately up to 4 times per year, with physician consultation up to 6 times per year. A distinguishing feature of this study compared with previous ones was the provision of remote support using a general-purpose smartphone communication app offered up to 12 times annually on an as-needed basis to enhance the continuity of in-person education effects. Patients were followed up on at average intervals of 3 months for up to 24 months. The primary end point was the mean difference in glycated hemoglobin (HbA1c) at each follow-up visit from baseline. For continuous glucose monitoring (CGM) users, CGM metrics were also evaluated.

RESULTS

The mean HbA1c level of study participants was 8.6% at baseline (mean duration of T1D 10.02, SD 16.10 y). The HbA1c level reduction in participants who received at least 1 structured educational session went from 1.63% (SD 2.03%; P<.001; adjustment model=1.69%, 95% CI 1.24%-2.13% at the first follow-up visit) to 1.23% (SD 1.31%; P=.01; adjustment model=1.28%, 95% CI 0.78%-1.79% at the eighth follow-up visit). In the adjustment model, the actual mean HbA1c values were maintained between a minimum of 7.33% (95% CI 7.20%-7.46% at the first follow-up visit) and a maximum of 7.62% (95% CI 7.41%-7.82% at the sixth follow-up visit). Among CGM users, after at least 1 session, the mean time in the target range was maintained between 61.59% (adjusted model, 95% CI 58.14%-65.03% at the second follow-up visit) and 54.7% (95% CI 50.92%-58.48% at the eighth follow-up visit), consistently staying above 54.7% (corresponding to an HbA1c level of <7.6%). The mean time below the target range (TBR) also gradually improved to the recommended range (≤4% for TBR of <70 mg/dL and ≤1% for TBR of <54 mg/dL).

CONCLUSIONS

The Home and Self-Care Program protocol for glycemic control in patients with T1D is effective, producing significant improvement immediately and long-term maintenance effects, including on CGM indexes.
Gender Equality Training for Students in Higher Education: A Scoping Review (Preprint)
Authors: Condron Claire , Power Mide , Mathew Midhun , Lucey Siobhan , Henn Patrick , Dean Tayna , Kirrane-Scott, Michelle , Eppich. Walter , Lucey Siobhan M.
Published: May 2024

UNSTRUCTURED

Despite recent improvements, gender inequality persists within the higher education sector, as evidenced by the proportionally greater number of student and academic leadership positions occupied by male students and staff. Gender equality training for students will build capacity to address biases and accelerate culture change in higher education institutes (HEIs). This scoping review maps the literature related to current best practice in gender equality training for students in higher education. Systematic database searches of peer-reviewed and grey literature were carried out and 3140 titles, 33 abstracts, and 52 full-text articles were screened for eligibility with 14 articles selected for inclusion. The selected studies detail a range of pedagogical approaches, including didactic lectures, participatory and co-design workshops, reflective writing, and service learning, with durations ranging from a single interaction to one year. Most articles reviewed do not explicitly state their study aims or research question, and the theoretical underpinnings are generally vaguely described. The longer term impact of most interventions is unclear, as evaluation metrics seldom go beyond the level of adoption. This scoping review shows that the literature base for gender equality training for third level students lacks coherence, highlighting the need for further work to evaluate its impact.
Facilitating Ulvan Extraction from Ulva lactuca via Deep Eutectic Solvent and Peracetic Acid Treatment
Authors: Ramadhan Wahyu , Alamsyah Al-din , Uju  , Hardiningtyas Safrina Dyah , Pari Rifzi Fariz , Wakabayashi Rie , Kamiya Noriho , Goto Masahiro
Published: May 2024

Ulva lactuca is a green seaweed and commonly referred to as sea lettuce and contains sulphated polysaccharides that have biological activity. Strong acids (HCl) and strong bases (NaOH) are commonly used as solvents in the conventional extraction process for ulvan, despite its lack of ecological sustainability. Deep Eutectic Solvent (DES) is an alternative to ulvan extraction solvent which is more environmentally friendly and has low toxicity. Ulvan extraction using DES with a temperature of 85-95ºC for 1 hour, and adding 2% peracetic acid pretreatment, 0.1%, 0.5%, and 2% peracetic acid posttreatment were conducted. Peracetic acid pre- and post-treatment (PAA) was carried out with a 1:10 (w/v) ratio at room temperature for 30 minutes. This study aims to optimize the use of DES in ulvan extraction with pre- and post-treatment of ulvan quality. The analysis performed included moisture content, yield, functional groups, sulphate content, and color. The test results revealed that ulvan treated with 2% PAA pretreatment had the highest moisture content and sulphate content, at 18.71% and 33.39%, respectively, while ulvan treated with 0.1% PAA posttreatment had the highest yield, at 41.96%. The addition of peracetic acid concentration can increase the color quality of the ulvan. PAA pre- and post-treatment had a significant effect on all ulvan quality parameters.
Studies on Encapsulation of Gas Releasing Agent in Ca-Alginate Beads and Controlled Release Pattern of the Beads
Authors: Peh Yee Ming , Haikal Izam Mohammad Afiq , Lee Boon Beng , Ma’Radzi Akmal Hadi , Kasim Farizul Hafiz , Mohd Johar Hafizah , Wan Yaakub Ahmad Radi , Saifuddin Md Nabil Ab Adzim , Lien Nguyen Thi Le
Published: May 2024

Calcium alginate beads have been used to control release gases and volatile compounds for agricultural applications, drug delivery, waste treatment, and food product enhancement. The release rate of the gas and vapor depends on the diffusion of gas and vapor through the Ca-alginate gel matrix. However, the knowledge about the effect of process variables on the diffusion rate of gas and vapor still needs to be improved. Therefore, this study aims to investigate the effect of alginate concentration, gas release agent concentration, and bead size on the concentration of gas released from Ca-alginate beads. In this study, calcium carbonate was used as the model gas release agent, encapsulated in Ca-alginate beads to release carbon dioxide when the beads reacted with an acetic acid solution. The results showed that the concentration of carbon dioxide released by the beads depended on the bead diameter. The gas release rate was increased when the diameter of the beads was increased. The total amount of gas produced by the large beads was observed to be higher than that of small beads. Compared to small beads, large beads take longer to react completely to produce carbon dioxide gas. It was also found that the amount of carbon dioxide produced by the Ca-alginate beads was inversely proportional to alginate concentration but directly proportional to calcium carbonate concentration. The results indicated that the gas diffusion rate of the Ca-alginate beads can be tailored by adjusting the process variables of the Ca-alginate bead encapsulation process.
Budidaya Mangrove Pada Kawasan Desa Mandiri PT Vale Indonesia Tbk
Authors: Achank Hasanuddin
Published: May 2024

Tujuan penelitian dari pengabdian kepada masyarakat ini ialah untuk melakukan proses peremcamaam, pembibitan dan pengadaan bibit, penananam, pemeliharaan serta penyulaman mangrove dalam program pengembangan kasawan desa mandiri. Pengabdian dilaksanakan dengan berbagai tahapan, yaitu dimulai dari pemantauan dan survey terhadap lokasi terkait dengan proses pembibitan, penanaman dan pemeliharaan mangrove yang disupport oleh PT Vale Indonesia Tbk. Hasil kegiatan memberikan kontribusi yang dapat menjaga kelestarian pesisir pantai/laut dari kerusakan-kerusakan yang diakibatkan oleh alam atau perbuatan manusia, Konservasi laut, Pengembangan ekowisata dan peningkatan ekonomi masyarakat.
Enhancing Anticancer Potential: Investigating the Synergistic Impact of Doxorubicin and Curcumin on HeLa and Vero Cells in Vitro
Authors: Aristiani Windy , Desvita Widea Rossi , Khayatulisma Dika , Edityaningrum Citra Ariani , Guntarti Any , Nurani Laela Hayu
Published: May 2024

(1) Background: Cervical cancer ranks as the fourth most prevalent cancer globally and in Asia, standing as the second most common in Indonesia. Despite its efficacy, doxorubicin chemotherapy is associated with significant side effects. To mitigate these adverse effects, a promising approach involves combining conventional drugs with curcumin. Both curcumin and doxorubicin have demonstrated cytotoxic effects against cervical cancer (HeLa). This research aims to determine the synergistic effect of the combination of doxorubicin and curcumin on HeLa and safety in normal cells (Vero cells). (2) Methods: This study adopted an experimental design utilizing doxorubicin and curcumin samples with HeLa and Vero cells. The investigation was initiated with cytotoxic and combination tests using the MTT method. The obtained results included IC50 values and combination indices, and the analysis involved a comparative examination of outcomes between HeLa and Vero cells. (3) Results: Cytotoxic tests revealed IC50 values for doxorubicin and curcumin on HeLa cells, measured in 2,17 ± 0,06 and 26,37 ± 2,00 µg/mL, and 17,32 ± 1,99 and 181,88 ± 30,48 µg/mL on Vero cells. Combination test results were represented by combination index .(4) Conclusions: The synergistic effect is observed at the combination of curcumin at a concentration of 9 μg/mL  and doxorubicin at a concentration of 0,125 μg/mL, resulting in a combination index of 0,50.  These findings suggest a promising avenue for enhancing the therapeutic potential of doxorubicin in cervical cancer treatment while minimizing adverse effects.
‘On Not Eating Rice Whilst Grieving’: An Exploratory Study on The Relationship Between Me Ro’ Death Ritual And Self-Management
Authors: Wuryaningrat Nikolas Fajar , Sumual Tinneke E.M. , Karinong Klauria , Apituley John
Published: May 2024

Me ro' tradition mandates families of a recently deceased person to abstain from consuming rice and entering rice fields until the deceased is buried. However, executing this tradition is considered challenging due to rice’s position as staple food with religious significance. Furthermore, the difficulty of adhering to Me ro' lies in the virtue of self-management of the family members. This exploratory study uses an observational method and in-depth interviews to collect information. Triangulation, involving documentation, recording, and peer-reviewed sources, is employed to ensure the validity, impartiality, and ethicality of the information. Two elders from Simbuang Village and two students who are originally from the village, but have studied outside of Simbuang Village serves as the informants of this study. The result of this study reveals Me ro' tradition to require stringent procedures, social sanctions, and economic obligations, which renders it to be challenging to fulfil. Moreover, to successfully accomplish Me ro', it depends on psychological, social, existential determinants, and lifestyle factors. Therefore, practicing Me ro' is not solely contingent on individual self-discipline, but also relies on the community's involvement to encourage, motivate, and supervise the Me ro' practice. In conclusion, it relies upon individual’s self-management and the community's ability to collectively support and supervise in the procedures.
Unravelling Conspiracy Theory Within Cultural Semiotics Framework as Narrative and Communication Strategies in Indonesian Social Media
Authors: Fadilah Eka
Published: May 2024

This paper aimed at exploring the meaning-making processes of conspiracy theories echoed by social media influencers as strategic narrative and communication systems. The topic was grounded in a cultural semiotic approach to dissect the aspects of signifier and signified as construed in social media. A nexus-case study was applied to make a deep analysis of meaning-making construction produced and re-produced by the influencers, taking up data triangulation derived from social media, theoretical frameworks, and empirical investigations. The study revealed that meaning was constructed through manipulating signifiers like Covid-19, Lato-Latto, and Dajjal worshipping, which were related to other floating signifiers to create polarization from the audience's perspective. Further, the meaning-making process was ontologically and epistemically baseless. Advanced recommendations are reiterated through this paper to provide a wide range of insight to cope with the issue presented.
Seat of the Divine Preserver: Prabudewa Iconographies of the Hamengku Buwana Dynasty
Authors: Supriyadi Matheus Raoul
Published: May 2024

For more than two-and-a-half centuries, the Sultanate of Yogyakarta has been under the rule of one dynasty of sultans called the Hamengku Buwana. The key to such an everlasting rulership by one dynasty is the use of narratives as well as symbolisms that support said narratives. In the case of the sultanate, the narratives relate to the concept of the sultan as a god-king, or in the Javanese term, prabudewa. In this research article, we will see how the dynasty found means of identification with the Hindu deity, Lord Vishnu, that strengthens the claim that the sultan is indeed a divine sovereign. The framework upon which this research is based is the symbolic framework, where cultural elements can be read as texts that narrate the innerworkings of a society. At the end of the day, the author found that the Hamengku Buwana dynasty has been using artistic iconographies within the royal court as a means to strengthen their identification as Lord Vishnu, the divine preserver of the universe according to the Hindu pantheon. The iconographies are spread throughout the royal court and can be found in various forms as well that one can still see even to this day, such as the royal coach, the sultan's throne room, and in Yogyakartan batik motifs.
Changes in CA 125 Level Pre and Post Ovarian Cancer Surgery
Authors: Aprivinta Sherlyana Mega , Pradjatmo Heru , Hadiati Diah Rumekti
Published: May 2024

Background: Ovarian cancer is one of the gynecological cancers that has a fairly high mortality rate and has a poor prognosis. Ovarian cancer management includes optimal operation followed by chemotherapy, which at follow up will have an effect on decreasing CA 125 levels. But in fact there are several studies showing increased CA 125. Given these differences in findings, this study attempted to evaluate the pre and post operation changes in CA 125 levels in ovarian cancer patients.Objective: This study aims to determine the changes in pre and post operation CA 125 levels in ovarian cancer patients. And to find out the optimal relationship between CA 125 level post operation and post operation.Methods: The type of research is an analytic study with a prospective cohort design. The source comes from secondary data taken from Simetris dr. Sardjito Hospital within 6 months.Results: The distribution of the age < 40 years was 11 and 19 were 40 years old. There was a significant change in pre operation log CA 125 levels (mean = 2,53 or 902,03U/ml) and post operation log CA 125 levels (mean = 1,92 or 406,23 U/ml). With a difference or delta mean of 0,61 or 495,80 U/ml and p value = 0.001. There was a significant difference in post operation log CA 125 levels between optimal and non optimal operation. Based on risk factors, there was a significant change or decrease in log CA 125 levels pre and post operation, but there was no significant difference in log CA 125 levels pre and post operation.Conclusion: There was a significant decrease in log CA 125 levels pre and post operation in patients with ovarian cancer who underwent operation. The post operation log CA 125 level in optimal operation is lower than in non-optimal operation.Keywords: CA 125, Ovarian Cancer, Operation, Optimal
Perbandingan Luaran Maternal dan Perinatal Kehamilan Terkonfirmasi Covid-19 antara Gelombang Pertama dan Kedua Pandemi
Authors: Irsan Raissa Alifia , Farhanah Nur , Trisetiyono Yuli , Cahyanti Ratnasari Dwi
Published: May 2024

Background : New cases of COVID-19 continued to emerge due to the new variants. Pregnant women are more susceptible to severe infections.Objective : To compare the effect of COVID-19 infection on maternal and perinatal outcomes in the first and second waves.Method : An analytical observational study with a cross-sectional design was used. Samples were selected by consecutive sampling from the medical record data of RSUP Dr. Kariadi Semarang, Indonesia, with 47 cases during the first wave (1 August 2020 to 14 May 2021) and 47 cases during the second wave (16 May to 30 September 2021). Data were analysed using univariate, chi-square, fisher’s exact, and logistic regression tests with a significant value of p <0,05.Results and Discussion : Pneumonia, ICU admission, and oxygen consumptions were higher in the second than the first wave as 87.23% VS 70.21%; p = 0.044, 36.17% VS 14.89%; p = 0.018, 65.96% VS 12.77%; p < 0.0001 respectively. The severe COVID-19 infection and maternal mortality increased in the second wave (51,06% VS 14,89%; p = 0.009; 29,79% VS 8,51%; p = <0.001). There were no differences in perinatal outcomes between the first and second waves such as fetal distress, fetal growth retardation, low birth weight, nICU admission, and mortality (0.00% VS 8.51%; p = 0.117, 0.00% VS 4.26%; p = 0.495, 12.77% VS 25.53%; p = 0.116, 12.77% VS 21.28%; p = 0.272, 4.26% VS 8.51%; p = 0.677). The incidence of COVID-19 infection in neonates remained low in both waves at 17.02% VS 12.77%; p = 0.562.Conclusion : Even though a high number of severe diseases to maternal deaths were found during the second wave, neonatal COVID-19 infections remained low.
Perbaikan Jatuh Tegangan dan Rugi Daya dengan Rekonfigurasi Jaringan Sambungan Rumah dan Rekonduktor Jaringan Tegangan Rendah pada Gardu Distribusi MI-44-150-21 PT PLN ULP Magelang Kota
Authors: Rizkiana Aldila Fajar , Saputra Yuris Mulya
Published: May 2024

Sistem kelistrikan di dusun Wonosobo disuplai oleh transformator distribusi dengan kapasitas 50 kVA. Terdapat 54 unit pelanggan dengan total daya kontrak terpasang adalah 31,5 kVA. Berdasarkan hasil pengukuran, tegangan terendah disisi pelanggan adalah 199 V berada di bawah tegangan nominal 231 V atau memiliki persentase jatuh tegangan sebesar 13,85% melebihi standar minimum jatuh tegangan 10%. Salah satu penyebabnya adalah banyak tarikan sambungan rumah di dusun Wonosobo melebihi standar PLN 56-1:1993 mengenai standar sambungan rumah. Dengan demikian perlu dilakukan upaya perbaikan meliputi rekonfigurasi jaringan sambungan rumah (SR) dan melakukan rekonduktor jaringan tegangan rendah (JTR) untuk mengatasi overload pada penghantar JTR. Rencana perbaikan disimulasikan dengan perangkat lunak ETAP 12.6.0 agar nilai jatuh tegangan dapat diperbaiki sesuai standar PLN No. 1 Tahun 1995 dan dapat mengurangi rugi daya. Berdasarkan hasil simulasi, setelah melakukan upaya perbaikan menggunakan 2 metode diperoleh nilai tegangan terendah menjadi 210,2 V dengan persentase tertinggi jatuh tegangan sebelumnya sebesar 12,42% menjadi 9,00%. Oleh karena itu, nilai jatuh tegangan yang didapat setelah perbaikan sudah sesuai dengan standar PLN yaitu di bawah standar minimum 10%. Setelah dilakukan perbaikan dengan dua metode, total rugi daya yang dihasilkan turun dari 1864,05 watt menjadi 1051,17 watt.
Komparasi Metode Manipulasi Baseline untuk Uji Diskriminasi Keberadaan Residu Pestisida pada Sayuran Sawi Hijau Berbasis Electronic Nose
Authors: Setiarini Abelta Mika , Sumanto Budi
Published: May 2024

Sektor pertanian menjadi pilar utama untuk keberlangsungan hidup manusia. Di antara hasil pertanian yang sering dikonsumsi adalah sayuran sawi hijau. Namun, aroma sawi hijau organik dan yang mengandung residu pestisida seringkali sulit dibedakan. Pengecekan kualitas mutu bahan makanan juga memerlukan biaya yang tinggi. Untuk mengatasi masalah ini, dikembangkanlah instrumen electronic nose. Electronic nose memiliki permasalahan sensor drift, yang dapat diatasi melalui teknik prapemrosesan data seperti manipulasi baseline. Terdapat lima metode manipulasi baseline yaitu difference, relative difference, fractional difference, log difference, dan normalization. Manipulasi baseline dan ekstraksi fitur menggunakan metode statistic dan fast fourier transform diterapkan pada hasil data akuisisi. Principal component analysis digunakan untuk melihat persebaran data yang telah diproses. Metode manipulasi baseline terbaik ditentukan berdasarkan nilai persen variansi pada PC 1 sebagai indicator utama. Hasil analisis menunjukkan nilai total PC mencapai 87,37% dengan nilai PC 1 dan PC 2 masing-masing adalah 79,02% dan 8,35%. Berdasarkan hasil analisis tersebut diperoleh bahwa metode manipulasi baseline terbaik adalah relative difference dan fractional diffenrence. Kedua metode manipulasi baseline tersebut efektif dalam meningkatkan tingkat diskriminasi data pada instrumen electronic nose. Dengan demikian, instrumen ini dapat membantu dalam penentuan kualitas dan diskriminasi jenis sayuran sawi hijau berdasarkan aroma yang dimiliki.
Analisis Kebutuhan Bank Kapasitor Untuk Perbaikan Faktor Daya di PT Beras Rajawali Menggunakan Optimal Capacitor Placement ETAP 19
Authors: Al Firdausi Barik Irfani , Auliq Muhammad A'an , Fitriana Fitriana
Published: May 2024

Saat ini, permintaan energi listrik terus meningkat karena kebutuhan yang bertambah, termasuk di sektor industri seperti PT Beras Rajawali yang terus memperluas fasilitas produksinya guna memenuhi permintaan yang semakin tinggi. Adanya peningkatan jumlah unit produksi akan terjadi penurunan faktor daya yang perlu segera diatasi. Salah satu cara untuk mengatasi atau mengurangi kerugian daya akibat faktor daya yang rendah adalah dengan memasang bank kapasitor. Pemasangan bank kapasitor ini diharapkan dapat bekerja secara efektif dan efisien sehingga perlu dilakukan analisis terlebih dahulu melalui simulasi sebelum dilakukan pemasangan bank kapasitor secara real. Metode analisis yang digunakan pada penelitian ini yaitu Optimal Capacitor Placement (OCP) menggunakan software ETAP. Hasil simulasi dan perhitungan menunjukkan bahwa pemasangan bank kapasitor pada bus yang mengalami penurunan faktor daya berhasil mengembalikan faktor daya menjadi normal. Hal ini terlihat ketika sebelum dipasang bank kapasitor, arus pada kedua mencapai 101,1 A dan 111,4 A, sedangkan setelah dipasang bank kapasitor, besarnya arus menurun menjadi 67,9 A dan 78,5 A.
Representation of Black People in Dahmer - Monster: The Jeffrey Dahmer Story
Authors: Daniela Lerissa , Kusumaningtyas Purwanti
Published: May 2024

This study examined the representation of color-based injustice in Dahmer – Monster: The Jeffrey Dahmer Story series shown on Netflix in September 2020. This series told about a serial killer to 17 men murdered and mutilated by Jeffrey Dahmer which happened in late 1980s until 1991 in Milwaukee, United States of America. 16 out of the 17 victims were black people, while Dahmer himself was a white man. Multimodal Discourse Analysis (MDA) theory, specifically the three metafunction framework by Kress and van Leeuwen (2021) was used to analyze the semiotic resources presented in Dahmer series, including dialogues, visual images, and gestures, to understand how these resources were interrelated in constructing the representation of black people in that series. Data was taken from the 10 episodes of the series. This research found four themes of black people representation. First was the stereotypical portrait of blacks as the poor and less educated than the sufficient whites. Second was the portrayal of discriminative treatment toward black people that strongly shown in the series. Third was how the colored people responded to the discrimination by speaking up for their rights. The series magnified the significance of the blacks and their fights for justice. Lastly was the holistic fights of the blacks for their rights became evident in the portrayal of the important figure to support the justice seeking. The series also highlighted the sustainable racial justice. In other words, the series had an intention to voice up the necessity of unity and mutual support in the society for preserving justice.
EXPERIMENTAL STUDY ON CREEP LOADING OF POROUS COAL UNDER DIFFERENT INFLUENCING FACTORS
Authors: Zheng Jiyu , Wang Longkang
Published: May 2024

After the gas drainage borehole is formed in the coal seam, its stress deformation process is a creep process without the influence of mining. By arranging boreholes on coal samples and carrying out creep loading test of porous coal through rock mechanics testing machine, the creep process of boreholes in actual coal seams is simulated. The results show that the creep loading test results of drilled coal are quite different from those of conventional loading. Creep loading produces large deformation due to rheological and aging characteristics. Compared with non-porous coal, the yield of drilled coal occurs earlier and the yield platform is wider during creep loading. Also, the larger the borehole diameter, the deeper the borehole depth, and the lower the peak stress. The up dip angle is easier to destroy than the down dip angle. Compared with hard coal, soft coal produces greater deformation under smaller peak stress. The research results have guiding significance for drilling gas drainage in the soft coal seam.
Tecnología lítica, procesos de producción y modos de hacer en campamentos de actividades múltiples de cazadores-recolectores de Antofagasta de la Sierra, Catamarca-Argentina
Authors: Bobillo Federico Miguel
Published: May 2024

In the context of their residential and logistical activities, hunter-gatherer groups set up multi- or specific-activity camps where they conduct subsistence practices and/or artisanal work. This research analyzes the technological strategies, operating procedures and knapping techniques used by hunter-gatherer groups at two multiactivity camps located in a quarry workshop in Punta de la Peña (Antofagasta de la Sierra, Catamarca). To that end, techno-morphological and morphological-functional analyses were conducted on complete lithic assemblages recovered in samplings and excavations in Camps 1 and 2 in Punta de la Peña supply and quarry area. The research verified the use of different criteria, procedures (bifacial or multifacial knapping) and technical gestures to obtain blanks from cores. It also recorded different ways of making shaped knapped tools, including bifacial thinning techniques (for bifaces and projectile points) and marginal retouching of edges and/or points (for scrapers and spokeshaves). The variability of the documented typological groups shows that, over millennia, people used different knowledge and techniques to work with rocks and create products.
Biofabrication, Characterisation and Antimicrobial Activity of CuO/Ag-based Material
Authors: Saklani Taru , Joshi Naveen Chandra , Jakhmola Vikash
Published: May 2024

In this work, Azadirachta indica leaf extract and the ultrasonic method were applied for the fabrication of a CuO/Ag-based nanocomposite. The CuO/Ag was characterised using different analytical methods such as FTIR, SEM, EDX, and XRD. The well diffusion method was used to evaluate the antibacterial activity of non-calcined and calcined CuO/Ag against some hazardous bacterial strains. After the incubation period, remarkable zones of inhibition were observed around the loaded CuO/Ag. The maximum zones of inhibition were found to be 17.9 (± 0.39), 20 (± 0.17), and 14.3 (± 0.31) mm for E. coli, S. aureus, and S. enterica, respectively. Experimental findings indicated that non-calcined CuO/Ag was a more effective antibacterial agent as compared to calcined CuO/Ag.
Smart Glass for Visually Impaired People
Authors: P Dr. Kavya A , Kurthukoti Anoushka Ameet , A Ayeesha Rida Khan , S Devika K
Published: May 2024

Abstract: This review paper aims to underscore the significance of inclusive technology in enhancing the lives of individuals with visual impairments and examine how smart wearable glasses are considered a potential solution for addressing challenges related to object detection. The blind community faces several obstacles in a world where visual information is dominant. The study examines the body of research on smart glasses and emphasizes how object recognition helps to improve spatial awareness. It highlights the revolutionary effect of these gadgets in promoting independence and enhancing accessibility for blind people by summarizing recent research. This succinct assessment seeks to add to the existing methods of inclusive technology by highlighting the exciting possibilities of smart glasses in empowering the blind population.
Assessment of Rooftop Rainwater Harvesting Potential: A Case Study for Nagaland
Authors: Tsopoe Y. S. , Sangtam L. , Umadevi S. , Chophy K. , Chewang K. N. , Chophi X. N. , Konyak H. P. , Lairenjam C.
Published: May 2024

Abstract: Water scarcity has become a serious global threat due to hazardous population growth frequent droughts and changing climate pattern (Carolina B. Mendez et. al). Water is scarce natural resource, even though 71% of land is covered by water out of total water on the earth near about 25% are fresh which is being utilized for various purposes viz. domestic, irrigation and industrial are common. Nowadays the need of commercial water is magnifying tremendously in a developing country like India which has long tradition of rural culture. Here in this study, an attempt was made to estimate the potential of rooftop rainwater harvesting in the state of Nagaland, India. The results showed that the total domestic water demand of Nagaland was estimated at 62,012,868,550 liters and domestic supply potential only from rooftop rainwater harvesting was estimated to fulfill about 64.70% of total water demand and the shortage which is about 35.3% can be through state governments water supply scheme, from the private sector and also other sources like pond, river, spring water, etc
Tocolytic effectiveness of nifedipine in management of preterm labor: A tertiary center experience
Authors: Firat Aysun
Published: May 2024

Objective: This study aimed to compare the efficacy of nifedipine use in our clinic for treatment of preterm labor with diferent effacement degrees, and to compare our results with the literature.
Methods: 440 singleton pregnant women with intact amnionic membrane pregnant women in their 23 and 36 weeks were retrospectively evaluated. Because of different criterias defining preterm labor in the literature, patients were divided into two groups as 4 or over contractions in 20 minutes and cervical opening at 2 cm and/or above and/or effachment at 80% or above (Group A, n=230) and 4 or over contractions in 20 minutes and cervical opening below 2 min and effechment below 80% (Group B, n=210). Descriptive statistics were conducted using chi-square and Mann Whitney U test, and statistically significance was p <0.05.
Results: Demographics, reproductive history and pregnancy weeks of the groups were similar. The average time between the start of tocolysis and the birth was 4 times higer in Group B (0.1-99.2, mean 28.4) than that of Group A (0.1-78.9, mean 7.4 days, p<0.001). Delay after tocoloysis at days 1 to 7 was statistically remarkable in Group B (p<0.001, for each). Preterm labor resulting in early birth was more remarkable in Group A in both before 34 weeks and 37 weeks (p<0.001, for each; n=88, 38.3% vs n=36, 17.1% and n=171, 74.3% vs n=98, 46.7%, respectively and n=269/124, 28.2 vs 61.1%). Delay with nifedipine at day 1 (87.5%), day 2 (79.1%), day 3 (74.8%) and day 7 (65.5%) was also compatable with the literature.
Conclusions: Nifedipine is an effective tocolytic agent in preterm labor regardless of the effachment degree.
Impact of Covid-19 Pandemic upon Iraqi women’s Commitment to Family Planning at Primary Health Care Centers in Baghdad City
Authors: Ghafel Hawraa Hussein
Published: May 2024

Objectives: To evaluate the impact of COVID-19 upon Iraqi women's commitment to family planning before and during COVID-19 pandemic
Methods: A descriptive design, correlational approach was conducted from November /2021 to July / 2022. The setting of the study including two primary health care centers in Baghdad City. A non-probability 'purposive sample' consists of (200) women at reproductive age (16-49) years old. Descriptive and correlational statistics were used for data analysis.
Results: The results of the study shows that regarding commitment to use of family planning methods among women before and during COVID19 pandemic; the “Use family planning methods” among (94.5%) before-COVID19 and (83%) during COVID19. there is high significant relationship between commitment to use of family planning before-COVID19 and during COVID19 at p-value= .001 respectively.
Conclusion: The pandemic has affected women’s commitment to family planning methods, as well as its impact on the type of method that used. Despite the pandemic family planning is very important to women’s reproductive health so, it is necessary to improve family planning information, services, and access.
Optimizing Treatment Quality in Head and Neck Cancer Therapy: Impact of Adaptive Intensity-Modulated Radiotherapy on Plan Quality and Tumor Volume Changes
Authors: Albosaabar Muntather Habeeb , Ahmad Rozilawati Binti , Alabedi Haydar Hamza , Mohamed Faizal , Yahya Noorazrul , Abouelenein Hassan , Mohamed Dalia Osama , Sayed Mona Mahmoud
Published: May 2024

Objective: This research analyses whether volumetric changes and PTV shifting affect adaptive intensity-modulated radiotherapy (IMRT) plan quality and head and neck cancer therapy.
Methods: The research was carried out at the Sohag Cancer Centre in Egypt, including a sample of 36 individuals diagnosed with head and neck squamous cell carcinoma (HNSCC). Patients were chosen on the basis of the following criteria: locally progressed and node-positive malignancy, oropharyngeal cancer, oral cavity cancer, and unknown primary. The research used dynamic intensity-modulated radiation therapy (D-IMRT) to establish treatment plans and Siemens SOMATOM DEFINITION CT scanners to acquire 3D anatomical images. A range of 1.64 to 2.12 Gy was observed for the median dosage per fraction. Using the conformance index (CI) and the homogeneity index, the quality of the plan was assessed (HI). The threshold for statistical significance was set at 0.05.
Results: The study analysed patients with unilateral and bilateral HNSCC tumors, with a majority having bilateral tumors. The findings demonstrated that the tumor PTV was significantly reduced as a consequence of the suggested adaptive radiation techniques. Both the homogeneity index and the conformity index were used to evaluate the plan's quality (HI). The maximal homogeneity index (HI) was reached after 7 and 14 fractions, respectively. The positive correlation between PTV reduction and CI after 7 fractions, while a negative correlation found after fractions 14 and 21. It was also shown that HI is positively correlated with PTV changes after 7 and 14.
Conclusion: The use of adaptive radiotherapy in intensity-modulated radiation therapy (IMRT) treatment planning improves plan quality and decreases error rates due to tumor margin movement. Following radiation fractions, PTV shifting affects the homogeneity index (HI).
Quantum copy-protection of compute-and-compare programs in the quantum random oracle model
Authors: Coladangelo Andrea , Majenz Christian , Poremba Alexander
Published: May 2024

Copy-protection allows a software distributor to encode a program in such a way that it can be evaluated on any input, yet it cannot be "pirated" – a notion that is impossible to achieve in a classical setting. Aaronson (CCC 2009) initiated the formal study of quantum copy-protection schemes, and speculated that quantum cryptography could offer a solution to the problem thanks to the quantum no-cloning theorem. In this work, we introduce a quantum copy-protection scheme for a large class of evasive functions known as "compute-and-compare programs" – a more expressive generalization of point functions. A compute-and-compare program CC[f,y] is specified by a function f and a string y within its range: on input x, CC[f,y] outputs 1, if f(x)=y, and 0 otherwise. We prove that our scheme achieves non-trivial security against fully malicious adversaries in the quantum random oracle model (QROM), which makes it the first copy-protection scheme to enjoy any level of provable security in a standard cryptographic model. As a complementary result, we show that the same scheme fulfils a weaker notion of software protection, called "secure software leasing", introduced very recently by Ananth and La Placa (eprint 2020), with a standard security bound in the QROM, i.e. guaranteeing negligible adversarial advantage. Finally, as a third contribution, we elucidate the relationship between unclonable encryption and copy-protection for multi-bit output point functions.
ANALISIS PERHITUNGAN NILAI PERTANGGUNGAN KECELAKAAN PADA PT. JASA RAHARJA DI BANDA ACEH MENURUT KONSEP KAFALAH
Authors: Friatna Ida , Maulana Muhammad , Fadila Alifa
Published: May 2024

Risiko yang kerap terjadi pada kecelakaan itu cenderung berbeda-beda mulai dari kecelakaan yang paling ringan hingga yang merengut nyawa. Dalam hal ini pihak PT. Jasa Raharja telah mengikat perjanjian dengan para peserta tentang jenis risiko dan tingkat premi yang akan diberikan ketika risiko itu terjadi. Namun, beberapa kasus cenderung terjadi perbedaan bentuk klaim yang dilakukan pihak peserta terhadap pertanggungan yang diberikan oleh PT. Jasa Raharja sehingga hal tersebut dapat merugikan pihak peserta yg telah membayar premi. Skripsi ini difokuskan untuk menjawab tiga hal penting, 1) Bagaimana penilaian terhadap kondisi objek pertanggungan untuk pengajuan klaim asuransi pada PT. Jasa Raharja, 2) Bagaimana kalkulasi dan penetapan nilai pertanggungan kecelakaan yang ditetapkan manajemen PT. Jasa Raharja Banda Aceh terhadap risiko yang dialami peserta, 3) Bagaimana perspektif konsep kafalah terhadap perhitungan nilai pertanggungan kecelakaan pada PT. Jasa Raharja. Penelitian ini merupakan penelitian kualitatif yang bersifat deskriptif analisis dengan pendekatan normatif sosiologis, dimana data yang diperoleh bersumber dari hasil pengamatan dan wawancara. Adapun hasil penelitian menunjukkan bahwa, pertama, penilaian terhadap kondisi objek pertanggungan dikategorikan dalam tiga golongan utama yaitu: perawatan (luka-luka), cacat tetap, dan meninggal dunia. Kedua, nilai pertanggungan yang diberikan oleh PT. Jasa Raharja berbeda-beda sesuai dengan risiko yang dialami peserta ketika kecelakaan terjadi. Ketiga, Pertanggungan yang dilakukan oleh pihak PT. Jasa Raharja terhadap korban kecelakaan lalu lintas sesuai dengan konsep kafalah yang telah dijelaskan oleh para fuqaha didalam fiqh muamalah terkait pertanggungan yang dilakukan pihak ketiga terhadap risiko yang terjadi berdasarkan kesepakatan pihak pertama, kedua dan ketiga. Namun, didalam konsep kafalah tidak adanya maksimal dari besaran biaya pertanggungan yang harus ditanggung kafil terhadap makful’ahu.
TRILHAR O CAMINHO NAS CIÊNCIAS DA NATUREZA DESDE A FORMAÇÃO AO INÍCIO DA DOCÊNCIA: UM OLHAR PARA AS PESQUISAS BRASILEIRAS
Authors: Souza Vanessa de , Santos Eliane Gonçalves dos
Published: May 2024

O presente trabalho possui como objetivo compreender o iniciar da docência em Ciências da Natureza, considerando os desafios, as potencialidades e a profissionalização docente. Para se constituir como profissional, é necessário trilhar caminhos que são encontrados desde a formação inicial e permeiam a subjetividade, pois o processo formativo está entrelaçado com o percurso de vida. Tomam-se como pressupostos teóricos a discussão sobre carreira, formação inicial e continuada, Ensino de Ciências e Desenvolvimento Profissional da Docência (DPD). Trata-se de um estudo de abordagem qualitativa do tipo revisão bibliográfica. Os dados empíricos foram coletados no acervo da Biblioteca Digital Brasileira de Teses e Dissertações (BDTD) do Instituto Brasileiro de Informação em Ciência e Tecnologia (IBICT), sem recorte temporal. A análise do material deu-se por meio da Análise de Conteúdo. Como resultado, foram encontradas duas categorias: I) desafios profissionais, os quais tratam dos desafios pessoais, estruturais e sociais da profissão docente, e II) profissionalização docente, que versa acerca das questões da formação inicial, a inserção na profissão, entre outros. Em suma, destacamos a importância da formação inicial para os docentes, a participação em grupos de trabalho, o compartilhamento de experiências entre os pares, o amparo e o apoio no momento de inserção profissional.
Formación en cultura ciudadana como contribución para la protección de los derechos humanos
Authors: Morillo Mosquera Leydi Johana
Published: May 2024

El municipio de Tumaco enfrenta una grave violación de derechos humanos debido al conflicto armado interno. Aunque se promueve la educación en derechos humanos, no se han logrado generar cambios significativos. Por lo tanto, la cultura ciudadana adquiere importancia al influir en la educación y concienciación sobre los derechos humanos. De ahí que la presente investigación tuvo como propósito analizar la cultura ciudadana como eje transversal de la convivencia ciudadana en los estudiantes de la Institución Educativa Técnica Agropecuaria Nuestra Señora del Carmen Espriella del municipio de Tumaco. En este orden de ideas se empleó el paradigma cuantitativo para diseñar un instrumento de medición de cultura ciudadana. Es importante mencionar que se retomaron las teorías de Abraham Magendzo K. y Paulo Freire, además de retomar antecedentes como la cultura ciudadana de Antanas Mockus y la investigación liderada por la administración municipal de Ibagué en su diseño y seguimiento a programas y políticas de cultura ciudadana. Como resultado de la investigación, se obtuvo que los niños, niñas y adolescentes sujetos de estudio en ocasiones no participan en la toma de decisiones al interior de la institución educativa y la comunidad, se evidenció carencia en el cumplimiento de normas, se avizoró vulneración a los derechos, se determinó que los participantes se preocupan más por sí mismos que por los demás, entre otros. Así, los resultados del instrumento de medición demuestran la carencia en cultura ciudadana y, por consiguiente, se hace necesario fortalecer el individuo a nivel personal y colectivo con el fin de vigorizar espacios de diálogo, relaciones basadas en el respeto y lograr el aprendizaje de comportamientos sociales significativos a fin de contribuir al reconocimiento de los derechos humanos y el bienestar social.
DICER1 Syndrome with an Intronic Germline Variant Causing Splice Alteration
Authors: Inoue Shutaro , Nakano Yoshiko , Tanaka Mariko , Yamada Yuta , Watanabe Kentaro , Hidaka Moe , Sekiguchi Masahiro , Kato Shota , Watadani Takeyuki , Fujishiro Jun , Kume Haruki , Ushiku Tetsuo , Kato Motohiro
Published: May 2024

Patients with DICER1 syndrome typically harbor a germline
truncating variant in the coding region. Here, we report a case of
DICER1 syndrome caused by an intronic germline variant. The
patient was diagnosed with pleuropulmonary blastoma at the 3 years of
age, and a somatic p.D1810Y, but not a germline variant in DICER1
was detected by whole-exome sequencing. After 13 years, he developed
urogenital embryonal rhabdomyosarcoma with a somatic p.E1813D in
DICER1. Further analysis using complementary DNA DICER1
confirmed that a germline p.I813Ffs*24 and c.2437-15T>G
caused the alteration. This report highlights the importance of a
germline-dedicated analysis covering introns.
Suggested title: Responsive complementary feeding practices in rural Rwanda: Perspective from mothers.
Authors: Ahishakiye Jeanine , Vaandrager Lenneke , Koelen Maria
Published: May 2024

Background: The feeding practices of the mothers, particularly
responsive feeding, are critical determinants of acceptance of food,
dietary intake as well as the growth of infants and young children
(IYC). Responsive feeding refers to the interactions between mother and
child that lead to a positive feeding experience, adequate dietary
intake and enhanced developmental opportunities. Little is known about
mothers responsive feeding practices in Rwanda. Therefore, this study
sought to explore mothers’ responsive feeding practices as well as the
factors that hinder the implementation of recommended practices among
mothers from rural Muhanga District. Method: This qualitative,
longitudinal study, recruited a purposive sample of 29 pregnant women
attending prenatal consultations in two rural health centers. They were
interviewed and mother-child interactions during mealtime were further
observed during one lunch meal feeding episode at 6, 9 and 12 months
postpartum. The interviews were recorded, transcribed and thematically
analyzed using qualitative software, Atlas.ti. Frequency distribution
was generated for each practice observed. Results: At 6 months,
most mothers reported to verbally encourage their children to eat during
feeding and the numbers increased over the age at 9 and 12 months
respectively. Less than a half, at all 3 time points, reported to allow
their child to self-feed, to smile and talking during feeding. During
the observation, the practices were even less than the reported at all 3
time points of the observations. The burden of other responsibilities
and poverty were perceived as the major barriers that made mother child-
interactions during feeding difficult. Conclusion: Findings
indicate that what mothers report may not always reflect the responsive
feeding practices performed during feeding . Nutrition
interventions in the study community should consider promoting
responsive feeding practices as well as addressing the issue of poverty
and the burden of other responsibilities that hinder mother-child
interactions.