bluuebunny/crossref_metadata_2025 huggingface dataset:
Training and Development Needs Analysis with Special Reference to Software Companies in Hyderabad
Authors: - SRIREKHA GANJI , - DR. G. VIDAY SAGAR RAO
Published: May 2024

This study investigates the how to examine the importance of training and development needs analysis in enhancing the employee efficiency in the social – environment and the workplace. Training and development is the most important weapon for the workplace to know the need analysis and effectiveness. Training is focus on today’s activities of the software companies in Hyderabad, India. The 40 sample size is used. This study concludes that there is an impact of training and development need analysis on the performance of workplace. Also it recognize organization and development is focus on the future tasks and responsibilities. Training and development is one of most important tool of HRM to increase organization’s output and competencies. This research is quantitative and secondary in nature. The data was collected from the different that the ability and skills of employee is helpful for the performance of organization and this skill are come from training and development. The study results illustrate the positive correlation between variables such as Training need analysis, Training transfer and employee efficacy, Learning and Job Satisfaction of the work place of the employee. These findings are significant to design training programs as part of the continuing professional development which are essential in achieving employee efficacy and leads to the benefits to the organization.
Knowledge Transfer of Site Based Construction Management Team of ABC Company: Basis for the Development of Knowledge Transfer Plan
Authors: - Francisco H. Bernal , - Ena A. Bernal
Published: May 2024

The study determines the readiness of ABC Company and the status of the project site based construction management team (CMT) on knowledge transfer (KT) as basis for the development of the proposed knowledge transfer plan (KTP).

Descriptive method was used to obtain information on the levels of readiness on organizational characteristics and resources requirement of ABC Company and on the gaps in terms of idea creation, sharing, dissemination, evaluation and adoption in the project site based CMT. Descriptive statistics was used to present the data on readiness; anything below 100% in terms of idea creation, sharing, dissemination, evaluation and adoption was considered a gap.

The study revealed that ABC Company has a moderately ready status on its readiness. Improvement was needed on KT strategy, rewards systems, knowledge hoarding, knowledge required, budget, and even on the core and support team that was essential in the development of the proposed KTP.

The project site based CMT had gaps to be attended to on idea creation, sharing and dissemination. Those gaps were considered valuable input in the development of the proposed KTP.

The development of the proposed KTP was grounded on quality management system that considered the readiness of ABC Company and the gaps found in the project site based CMT as inputs. The proposed KTP composed of four stages, namely, Management Responsibility, Resource Management, Knowledge Transfer Realization and Measurement, Analysis and Improvement. Intervention strategies presented in the KTP would address the particular area determined to be either absent or not consistently implemented with feed forward and feedback for continual improvement.
Campus Navigation using Augmented Reality and Virtual Reality
Authors: - Mr.  Jaydeep Lokhande , - Mr. Aayush S Bhuvad , - Mr. Aman Bendre , - Mr. Rusheil Bath , - Mr. Prathamesh Bodhankar , - Mrs. Madhuri Rao , - Mrs. Seema Idhate
Published: May 2024

With the rapid advancement of Augmented Reality (AR) and Virtual Reality (VR) technologies, there has been a growing interest in leveraging these immersive
technologies for enhancing campus navigation experiences. This paper presents a research study focused on designing and implementing a campus navigation system for the Maharashtra Institute of Technology World Peace University
(MIT WPU) using AR/VR technologies. The proposed system aims to provide students, faculty, and visitors with an intuitive and immersive wayfinding experience, facilitating navigation across the expansive campus grounds. The core features of the proposed campus navigation system include real-time location tracking, interactive campus maps, personalized route planning, and integration with campus services and facilities information. The AR component overlays digital navigation cues and points of interest onto the user's physical
surroundings, enhancing spatial awareness and providing contextual information. The VR component offers an immersive 3D visualization of the campus environment, allowing users to explore virtual replicas of buildings,
landmarks, and amenities. The research methodology involves a multi-stage process, beginning with requirements gathering through stakeholder interviews and user surveys to understand the navigation challenges faced by campus users. Based on the gathered requirements, a prototype AR/VR campus navigation application is developed, leveraging state-of-the-art AR/VR
development tools and technologies
पाकिस्तान के आर्थिक संकट में चीन की ऋण-जाल कूटनीति का प्रभाव : एक मूल्यांकन
Authors: - Dr. Satish Chandra Pandey , - Vishal Panday
Published: May 2024

बाहरी ऋणों पर निर्भरता ने न केवल पाकिस्तान पर कर्ज का बोझ बढ़ा दिया है, बल्कि भविष्य में इन ऋणों को चुकाने की देश की क्षमता को लेकर भी चिंताएं बढ़ गई हैं। चीनी ऋण जाल कूटनीति ने पाकिस्तान के आर्थिक संकट को और बढ़ा दिया है, क्योंकि इन ऋणों की शर्तें अक्सर चीन के पक्ष में होती हैं, जिससे पाकिस्तान को अपने पुनर्भुगतान दायित्वों को पूरा करने के लिए संघर्ष करना पड़ता है। इस ऋण जाल कूटनीति के परिणाम आर्थिक क्षेत्र तक ही सीमित नहीं हैं, क्योंकि इसने राजनीतिक बहस भी छेड़ दी है और पाकिस्तान की संप्रभुता और चीन के साथ उसके संबंधों पर भी सवाल उठाए हैं। इस शोध-पत्र ने वर्तमान समय में पाकिस्तान के सामने आने वाले वित्तीय मुद्दों पर ध्यान आकर्षित करने का प्रयास किया है और कैसे राष्ट्र-राज्य न केवल आर्थिक उथल-पुथल में है, बल्कि चीन के साथ एक जटिल रिश्ते में भी है। इस शोध-पत्र में यह सवाल उठाया गया है कि क्या पाकिस्तान चीनी ऋण जाल में है, जिसमें पाकिस्तान में ऋण की प्रकृति, ऋण और संप्रभुता के बीच संबंध और आधुनिक समय में ऋण साम्राज्यवाद से कैसे जुड़ा है, इसकी जांच की गई है। इस शोध-पत्र ने सुझाव दिया है कि पाकिस्तान कर्ज के जाल में फंस गया है और यह सुझाव देने के लिए सबूत प्रदान किया है कि यह जाल चीन को लाभ पहुंचाता है और पाकिस्तान को कमजोर करता है, राज्य की संप्रभुता को खतरे में डालता है और पाकिस्तान को चीन के लिए लाभकारी गठबंधन में फंसाता है। नई सहस्राब्दी के बाद से पाकिस्तान की अर्थव्यवस्था कर्ज में डूब गई है। चीन-पाकिस्तान आर्थिक गलियारे के विकास के साथ चीन पाकिस्तान के ऋण चक्र का एक अभिन्न अंग बन गया है। इस बड़े पैमाने की बुनियादी ढांचा परियोजना ने सड़कों, रेलवे और बिजली संयंत्रों के विकास के साथ पाकिस्तान के लिए वित्तीय वरदान प्रदान किया है।
Strategies for Prevention and Control of Air Pollution in India at Central Level
Authors: - JIWAN JYOTI
Published: May 2024

Environment pollution has become one of the chief threats to the survival of mankind. India faces severe environmental deterioration. It is a wide reaching problem and it is likely to influenced the great human health. This paper provides the insight view about the affects of air pollution on human beings by diseases, problems and functioning of pollution control board. Various studies found that the every age group is facing life threatening diseases like cancer, asthma etc due to pollution. Various strategies enacted by government from the recent issue of stubble burning to control pollution were to lessen the crop burning which were implemented by government which was not implemented on the serious note. Though the pollution control board plays the successful role to control pollution but still it is increasing day by day.
Tourism Performance and Economic Development in India
Authors: - KALEESHWARI.S , - SAJJAN.S
Published: May 2024

There are several reasons to travel, and these reasons combine to form the tourism industry, which is one of the world's major service sectors in terms of sales and earnings in foreign currencies. It becomes clear that tourism is a powerful stimulus for inclusive societal growth, which benefits both general development and the reduction of poverty. Worldwide recognition is accorded to its key position and significance in propelling economic improvement and augmenting employment prospects. India's tourism industry is expanding rapidly, with great potential for generating employment and foreign exchange profits in addition to driving the country's overall economic and social progress.
India has many tourist spots that are popular with both domestic and foreign visitors, such as Mysore, Delhi, Goa, and Amritsar. Particularly important for the expansion of India's services sector and a major source of job creation is the tourism sector. The tourist sector in India can significantly boost infrastructure development due to its enormous growth potential. Additionally, it can promote several other economic sectors through interdependent linkages, promoting cross-sectoral synergies and advancing total economic development in industries including construction, handicrafts, horticulture, poultry, transportation, and agriculture.
Mechanism and Study on Ball End Magnetorheological Fluid Finishing Process
Authors: - Anmol Sharma , - M.S.Niranjan , - Aditya Mudgal , - Vansh
Published: May 2024

The primary object of this research is to explore the capacities of BEMRF. Traditional polishing methods for glass commonly face challenges in reaching nanoscale precision and uniformity. In BEMRF, by controlling rheological properties of the MR fluid, we can tackle these challenges and potentially surpass the limitations of conventional techniques. The study includes the application of magnetorheological (MR) fluid with suspended magnetic particle abrasives to accomplish precision finishing by the manipulation of magnetic fields.
Revolutionizing Student Accommodation: A MERN-Based Rental System For Seamless Property Management
Authors: - Arvind Nair , - Aryan Sadvelkar , - Sarvesh Damle , - Neha Kudu
Published: May 2024

This web application facilitates the registration of individual homes or apartments to streamline the process of finding ideal rental properties. Users can conveniently search for their next rental in targeted areas through a user-friendly interface. The platform is designed to cater to diverse real estate needs in India, including property buying, selling, and leasing. It serves as a valuable tool for investment by maintaining a comprehensive database of various properties and agent information. Not only does it assist users in accessing updated property information globally, but it also enables agents to manage and update their listings. The platform alleviates the complexities associated with traditional property search methods by offering a simplified online form, minimizing the need for individual agent communication, appointment scheduling, and time coordination
Understanding the Roles of Family, Community in Visually Impaired & Low Vision Student’s Life
Authors: - Visha
Published: May 2024

The objective of this paper is to acquire an efficient understanding of the roles of family,how family support to attain their goals towards life . Family plays an important role in contribution in promoting enrichment,support of the overall quality of lives of the visually impaired student. In the personal and professional lives of the visually impaired student, there are number of functions and daily living activities, which they are required to carry out smoothly. These activities carried out may be on one’s own or perform with help and assistance from family or dear ones. For example, in the pursuance of educational coursers or programs within institutions of all levels, the student are required to deal with special educators, supervisors, visually impaired or sighted classmates and other staff members. Hence, development of consensus with them is regarded to be of sheer significance. On the other hand, within home environment , family members need to work in co-ordination with each other to promote each other’s well-being ,mental health and goodwill. The visually impaired students implement a range of work functions and responsibilities in compliance with protocols and guidelines. The family and community members, particularly special educator and service providers need to be provided with adequate information in terms of methods and procedures of initial phase of learning . Consequently, duties and responsibilities should be carried out in a well-ordered and disciplined manner among family ,community and special educator. Therefore, it is well-understood, roles of family ,community members and special educator are acknowledged to a major extent. The main concepts that are taken into account in this research paper are, roles of family ,roles of community members and roles of special educator in visually impaired student life.
Exploring Dissent and Critique in Anti-war Literature: A Comparative Examination of Narrative Styles in Dalton Trumbo's Johnny Got His Gun and Kurt Vonnegut's Slaughterhouse-five
Authors: - Kamakshi Singh , - Dr. Shuchi Agrawal
Published: May 2024

Narrative techniques are poweful tools in conveying dissent and critique in Anti War literature. This paper aims to study and analyse Dalton Trumbo’s Johnny Got His Gun and Kurt Vonnegut’s Slaughterhouse Five with the objective of exploring the narrative techniques employed by each author to express dissent and critique against war. The paper also aims to trace the similar and distinct features of narrative styles in the two works to highlight how two different narratives which are the results two World Wars strive to achieve the same goal, that is, to portray the incomprehensible and utterly unjustified human cost of wars. sheds light on the impact war and the criticisms of war have on literature.
Relationship between Personality Traits and Academic Procrastination among College Students: A Correlational Study
Authors: - Aditi Nigam , - Namita Srivastava
Published: May 2024

In this study, the relationship between Personality Traits and Academic Procrastination of one hundred undergraduate students was investigated. The study was conducted with 100 Indian students who were engaged in different educational programmes of graduation at various higher education centres of Lucknow, Uttar Pradesh and Delhi, India. The age of participants ranged from 18 to 25 years. Data collection tools included the Procrastination Assessment Scale for Students (Rothblum & Solomon, 1984) and the Big Five Inventory. Correlational analysis revealed that academic procrastination was found to have a negative correlation with extraversion alone, while it did not significantly correlate with the other Big Five qualities (conscientiousness, agreeableness, openness, and neuroticism). These findings suggest that extraversion may mitigate undergraduate students' inclination for academic procrastination.
Exploring Gender Differences in Scientific Aptitude among Secondary School Students: A Comparative Analysis Between Boys and Girls
Authors: - Kapil Kalita , - Pranab Saikia
Published: May 2024

Present study explores the Numerical ability and Science information (Scientific aptitude) among boys’ and girls’ students. It is aimed to find out the difference between boys’ and girls’ students in terms of Numerical ability and Science information. A sample of 100 (50 each from boys and girls) students has been taken from government secondary schools of Goalpara district, Assam. For the selection of sample schools, Researcher used random sampling technique. The data were collected with the help of standardized tool. For the research work, researcher used Scientific Aptitude Test Battery (SATB) developed by Agarwal, K.K and Aurora, S. In this study descriptive research design is used. The study employed quantitative method and include standardized tests. The major findings of the study revealed that the Boys possess more Numerical ability than Girls. Again, there is no informational difference between boys and girls in the field of science.
Case Study of Skilful Use of LLM-Based Generative AI in Management of a Hypothetical Business
Authors: - Dr A.L.Ravimohan , - Dr Vikas Sahasrabudhe
Published: May 2024

Now that generative AI technology products are already spreading worldwide and are improving their capabilities very fast, it is high time we examine what it can do to decision making, which is the essence of managing businesses. The present paper has used an innovative methodology where one of the currently available Large Language Model based product, namely ChatGPT, is given a series of questions/prompts to use its own capabilities to give its self-assessment of supporting the different dimensions of managing a business. Multiple conversations illustrated the need for well-structured prompts/questions to get the most out of ChatGPT, otherwise it can get confused and provide illogical response. The quality of mutual learning improves by constructive feedback between the human interlocutor and generative AI. Probing it further with multiple scenarios for a hypothetical mid-sized business has verified and confirmed those self-assessments. The insights and conclusions drawn from those conversations are that skillful use of the LLM-based generative AI products can assist human managers in making better quality decisions at all levels of management in a timely manner. Senior managers of businesses need to begin an effort to test-drive an available LLM-based generative AI product and plan to leverage it in the ongoing management to become a learning organization in the interest of the business.
The Nuanced Dance of Foreknowledge: A Reflection on Events and Choices
Authors: - Sanjay Mathur , - Sunil Maria Benedict
Published: May 2024

Foreknowledge, the ability to possess knowledge or awareness of events before they happen, introduces a fascinating dimension to our understanding of time and causality. In exploring this concept, it is crucial to recognize that foreknowledge is not causative; it doesn't bring about the events it predicts. This essay delves into the predictive nature of foreknowledge, the role of human decision-making, the interplay of randomness and probability, the impact on personal responsibility, and engages in thought-provoking discussions on determinism vs. free will, ethical considerations, embracing uncertainty, impact on planning, and the psychological effects of knowing about future events.
In-silico Docking and ADMET: Recent Innovations of Carvone
Authors: Srivastava Snigdha , Sinha Reema , Lavhale Pallavi M. , Kurmi Rajan K.
Published: May 2024

For the almost 500 decades, naturally occurring plant products always showed a narrative role to society for their effectiveness against several diseases. Carvone is a mono-terpenoid which is obtained as an essential oil obtained from Anethum graveolens (dill) and Carum carvi (caraway) oils, S(+) enantiomer and the (-R) enantiomer of carvone as a primary constituent of Mentha spicata (spearmint) oil also found in Calamintha officinalis (calamint) oil. As Carvone has shown a very less toxic effect. S(+) Carvone also acts as an anti-epileptic agent, (S &R) Carvone has shown much more potent activity when compared to (R) species of carvone. By performing In-silico docking studies of S(+) Carvone it has been observed that it is quite safe and potentially effective as an anticonvulsant agent, antispasmodic agent, antifungal agent, also as a cardiovascular agent etc. Carvone has a high permeability to GI absorption and also it follows the Lipinski rule (0 violations). Although, Carvone has less toxicity while crossing the blood-brain barrier. Docking studies of carvone is suggesting that it can be used for many advancements of the drug to achieve potent results in different pharmacological aspects.
The Molecular Docking Studies of Benzimidazole Analogues as Novel Anti-Inflammatory Agents
Authors: Chauhan Himanshu , Bansal Sandeep K. , Agrawal Anurag
Published: May 2024

Introduction: The benzimidazole nucleus is an integral part of legion bioactive heterocyclic compounds that are of great interest due to their various biological and clinical properties. The primary goal of this research is to design (in-silico) novel benzimidazole chemical entities as anti-inflammatory and analgesic agents.Material and Method: Molecular docking calculations were carried out to identify the interactions of designed benzimidazole analogues with COX-2 (PDB ID: 6COX). The docked complex conformations were studied in terms of binding energy, hydrogen bonding, and hydrophobic interactions. Molecular docking experiments were carried out at MGL Tools 1.5.7 software suite AutoDock 4.2.6.Results And Discussion: The Bindings revealed that the four novel molecules had binding energy greater than Indomethacin (Standard molecule). 2-fluorophenyl derivative has a binding energy of -11.34 kcal/mol and binding interactions with amino acids; (vizALA:199, PHE:200, HIS:207, ASN:207, HIS:386, HIS:388, LEU:390, LEU391).It Identifies benzimidazole analogues as promising molecules for anti-inflammatory activities comparable with standard.
Techniques for Metal Ion Determination in Samples
Authors: Gupta Krishna , Khobragade Saumyata , Ukey Anjali , Pounikar Anita , Umekar Milind
Published: May 2024

In human body building as well as in plants Metal ions play a vital role in vital functioning such as in various food chain reactions. Due to increase in industrialization everyday various industrial wastes contaminated with metal ions and metalloids. Several enzymes need them for their catalytic action, and their absence can cause a number of illnesses in humans. When this metal ions concentration level increases above the certain limits, it is harmful to human, animals, plant as well as aqua system. Because various essential biological processes in humans depend on metal ions, their absence or scarcity may result in diseases. In pharmaceutical sectors various transition metals are used as catalyst to improve kinetics of reaction. Therefore, it is necessary to determine concentration of metals ions whether it is present in within the limits, otherwise excess of its concentration may leads to toxicity in body. Also, the advisory body has made some regulatory guidelines to monitor and control levels of metals ions in food, environment and medicines. Hence more precise, accurate, economically acceptable, sensible and selective method are required to detect metal ions concentration in pharmaceutical, environmental, agrochemical and aquatic samples as well as in body tissues/fluids is also essential. Hence in our review we try to sum up various metal ion detection techniques, there mechanism and principle behind detection of heavy metal ion detection and instrumentation. The given methods are more sensitive at very low detection limits of up to pictogram level, accurate and more precise levels detection has been achieved.
Effectiveness of Midwifery Care for Family Planning (KB) Acceptors with IUD (Intrauterine Device): Study in Kayu Kul Village, Pegasing, Central Aceh, Indonesia
Authors: Hidayana  , Irdayani  , MS Sri Wahyuni
Published: May 2024

Family planning (KB) is one of the Indonesian government's priority programs to control the rate of population growth. IUD (Intrauterine Device) is an effective and popular family planning method in Indonesia. Quality midwifery care is important to ensure successful IUD use and increase acceptor satisfaction. This study aims to analyze the effectiveness of midwifery care for family planning acceptors with IUDs in Kayu Kul Village, Pegasing, Central Aceh, Indonesia. This study used a cross-sectional observational design involving family planning acceptors with IUDs in Kayu Kul Village, Pegasing, Central Aceh, Indonesia. Data was collected through structured interviews and observations of midwifery care provided to acceptors. Data were analyzed using univariate and bivariate analysis with the Chi-square test. The results showed that the majority of family planning acceptors with IUDs (80%) received effective midwifery care. Effective midwifery care includes: complete health screening, comprehensive education about IUD use, counseling about IUD side effects and complications, and regular monitoring of IUD use. Acceptors who received effective midwifery care had a higher level of satisfaction (90%) compared to acceptors who did not receive effective midwifery care (60%). Effective midwifery care has been proven to increase family planning acceptor satisfaction with the IUD. Therefore, it is important to improve the quality of midwifery care at Health Centers to ensure successful use of IUDs and increase acceptor satisfaction.
Interventional Intensive Care in Postoperative Period of Gastric Surgical Repair Due to Perforated Peptic Ulcer Disease : A Case Report
Authors: Kahar Liliriawati Ananta
Published: May 2024

Introduction: Perforated peptic ulcer is the most common indication for emergency gastric surgery. good management of postoperative peptic ulcer perforation patients in the ICU will reduce patient mortality rates.
Case presentation A 76-year-old male patient presented with a major complaint of pain throughout the abdomen that had worsened since 1 day, the abdominal pain had been felt for 4 days before admission. The patient had a history of painkiller drug consumption routinely for 3 years. The patient’s vital signs were normal, with a qSOFA score 1 and a VAS score 5. Abdominal physical examination showed the abdominal distended, no visible contour and no visible peristaltic, decreased bowel sound, and there is tenderness and rebound tenderness at the whole abdomen Patient was taken up for emergency laparostomy, then the patient underwent diagnostic laparoscopic in an elective setting with intraoperative findings of gastric perforation, then patient continued with the gastric repair. In the postoperative period, the patient was treated in the ICU of Dr. M. Djamil General Hospital.
Conclusion: Intensive care management for post-gastric repair surgery patients is generally the same as for other abdominal surgery patients. The intensive care management needs comprehensive treatment, starting from oxygen therapy, monitoring, analgesia, fluid therapy, antibiotic therapy, glycemic control, and nasogastric tube nutrition.
Nano Revolution: Smart Therapeutics Unleash with Nanomaterials
Authors: Bikash Medhi  , Charan Shiv , Soloman Singh Rahul , Gladson David Masih  , Benjamin Suroy
Published: May 2024

Nanotechnology explores substances and technologies organized at the nanoscale level, measuring one billionth of a meter in at least one dimension. This field of study encompasses both science and engineering1. At these scales, the individual molecules and interacting groups of molecules play a crucial role in determining the bulk macroscopic properties of materials or devices. The ability to manage the fundamental molecular structure grants control over the macroscopic chemical and physical properties2. In the realms of physiology and medicine, there are intriguing applications involving substances and tools designed to precisely interact with the body at subcellular or molecular dimensions. These advancements hold promise for targeted interventions and therapies, ushering in a new era of precision medicine. This may result in tailored, tissue- and cell-specific clinical applications that aim to maximize therapeutic benefits while minimizing adverse consequences. The scientific and technological dimensions of nanotechnology, are accompanied by an exploration of potential therapeutic applications. It is essential to recognize that nanotechnology does not exist in isolation; rather, it emerges from the synergistic convergence of established disciplines such as biology, chemistry, physics, and materials science. This interdisciplinary approach provides the foundational knowledge necessary for advancing these cutting-edge technologies.
An Overview of Self Nano-emulsifying Drug Delivery Systems for Enhanced Solubility and Dissolution for Anti-cancer Drugs
Authors: Kharat Amol , Nikam Savita
Published: May 2024

The current review aims to explore recently identified chemical compounds, particularly focusing on the challenge posed by the poor water solubility of many existing drug molecules. This limitation significantly affects the successful development and marketability of new pharmaceuticals, as the dissolution phase often becomes the bottleneck in the process. Crafting formulations becomes crucial in enhancing the absorption and, consequently, the oral effectiveness of these drug prospects. Given the prevalence of various diseases such as cancer, AIDS, HIV, and chronic inflammation among humans, optimizing drug delivery methods becomes pivotal to achieving maximum therapeutic benefits with minimal side effects. Innovative drug delivery systems like self-nano-emulsion are introduced, offering protective measures for medications, augmenting their characteristics, and elevating solubility and bioavailability. Furthermore, this study aims to enhance the chemical and physical stability of these compounds during extended periods of storage. Ultimately, this research endeavours to provide insights into the efficacy of self-nano-emulsion in enhancing solubility and bioavailability, thereby aiding researchers in comprehending its potential applications.
Design and Development of Fast-dissolving Tablets of Apixaban using Single Coprocessed Excipient
Authors: Jaiswal Sourabh , Kanugo Abhishek
Published: May 2024

Background: Apixaban is administered orally as an anticoagulant action and minimizes the chances of strokes and systemic embolism. The conventional film-coated tablet showed less bioavailability due to its minimal solubility in the gastrointestinal tract. 
Rationale: The goal of designing the current analysis is to prepare a prompt release tablet using a single Coprocessed excipient which minimizes multistep processing, time, and cost effectiveness.
Methods: The prompt release tablets of Apixaban were developed by direct compression technique using multifunctional material like Prosolve ODT G2 and Prosolve Easytab. Drug excipients inertness was confirmed with FTIR and DSC. Flowing characteristics of Apixaban and co-processed excipients were evaluated in terms of Carr’s index, Angle of repose, and Hausner’s ratio. These co-processed excipients indicated exceptional flowing and compression characteristics. The ready tablets were assessed for weight variation, hardness, friability, dispersion time, disintegration, and dissolution studies.
Results: Among 12 batches, the least disintegration time was shown with C6 with a cumulative drug release of 99.06 % within 25 min. The optimized batch C6 was highly stable when tested under stability guidelines at 40 0 C and at 75 % relative humidity.  
Conclusion: Among these co-processed excipients, Prosolve Easytab SP was found the best one for direct compression intended for the immediate or fast dissolving tablets.
Advancement in Generation and Application of Microfluidic Chip Technology
Authors: Savitri Goparaju
Published: May 2024

Microfluidics is an interdisciplinary topic of research that draws inspiration from other areas such as fluid dynamics, microelectronics, materials science, and physics. Microfluidics has made it possible to create microscale channels and chambers out of a broad variety of materials by borrowing ideas from a number of different fields. This has opened up exciting possibilities for the development of platforms of any size, shape, and geometry using a variety of approaches. One of the most significant advantages of microfluidics is its versatility in applications. Microfluidic chips can be used for a variety of purposes, such as incorporating nanoparticles, encapsulating and delivering drugs, targeting cells, analyzing cells, performing diagnostic tests, and cultivating cells. This adaptability has led to the development of several device-like systems for use in a range of settings. In this study, we explore cutting-edge novel applications for microfluidic and nanofabrication technologies. We examine current developments in the area of microfluidics and highlight their potential for usage in the medical industry. We pay special attention to digital microfluidics, a recently developed and very useful technique for illness diagnosis and monitoring. The originality of microfluidics is found in the fact that it allows for the miniaturization of complex systems and processes, paving the way for the creation of cutting-edge gadgets with wide-ranging practical applications. Microfluidics has the potential to transform various fields, including medicine, biotechnology, environmental monitoring, and more. The development of novel microfluidic platforms, coupled with advancements in digital microfluidics, promises to revolutionize the way we diagnose, treat, and monitor diseases.
Umela inteligencia, Chatovacie HR roboty a ich implementácia do učebných osnov
Authors: Kostrec Matej
Published: May 2024

Predkladaný príspevok si kladie za cieľ byť podnetom pre rozšírenie učebných osnov na Univerzitách a iných Vysokých školách zabezpečujúcich vzdelávanie v oblasti riadenia ľudských zdrojov. Môže byť podkladom pre prednášku o vplyve a spôsobe implementácie AI v predmetnej oblasti, ktorá ponúka široké spektrum nových prístupov a nástrojov na zlepšenie náborových procesov, profesijného a osobnostného rozvoja zamestnancov, hodnotenia ich výkonu i efektívnejšieho plánovania ich kariéry.
Umělá inteligence a její budoucnost v managementu vzdělávání
Authors: Petrů Naděžda , Crnadak Oskar , Černohorský Adam
Published: May 2024

Rozvoj digitálních technologií vzbuzuje rostoucí zájem mezi výzkumnými pracovníky, studenty, manažery, odbornou i laickou veřejností. Tato studie slouží jako předběžná a průzkumná kompilace odborných textů zaměřených na možnosti využití umělé inteligence v různých oblastech managementu, včetně vzdělávání. Aplikace umělé inteligence se v podnikovém managementu i ve vzdělávání v dynamickém digitálním věku celosvětově značně rozšířila a zvýšila. Systematizovaný přehled především aktuální literatury uplatňuje smíšený, kvantitativní a kvalitativní přístup využívající různá výzkumná paradigmata. Syntetizuje poznatky z 92 zdrojů, přehledových článků a poskytuje holistický pohled na efektivitu a potenciál AI nejenom ve vzdělávacím kontextu. Diskutuje trendy, ale i rizika využití AI v managementu a ve vzdělávání. Aplikační část textu uvádí příklady s tématikou AI ilustrující multidisciplinaritu tématu a množství stakeholderů, kteří jsou AI ovlivnění nebo ji sami ovlivňují. Představují náměty, příležitosti a výzvy umělé inteligence pro VŠFS, a.s.
První zákon o umělé inteligenci na světě (Akt o umělé inteligenci)
Authors: Karabec David
Published: May 2024

Umělá inteligence („AI“) je rychle se vyvíjející skupina technologií, které se podílejí na široké škále hospodářských, environmentálních a společenských přínosů v celém spektru průmyslových odvětví a sociálních aktivit. AI může ale také zároveň v závislosti na okolnostech týkajících se jejího konkrétního uplatňování, používání a úrovně technologického rozvoje vytvářet rizika a působit újmu veřejným zájmům a základním právům, které jsou chráněny právem Unie. Akt o umělé inteligenci má zlepšit fungování vnitřního trhu stanovením jednotného právního rámce pro AI, zejména pro vývoj, uvádění na trh, uvádění do provozu a používání systémů umělé inteligence v souladu s hodnotami Unie, podporovat zavádění důvěryhodné umělé inteligence zaměřené na člověka a zároveň zajistit vysokou úroveň ochrany zdraví, bezpečnosti a základních práv zakotvených v Listině základních práv Evropské unie, včetně demokracie, právního státu a ochrany životního prostředí, před škodlivými účinky systémů AI v Unii.
La superioridad del hombre blanco en la colonización del pensamiento hispanoamericano contemporáneo
Authors: Buitrago Ramiro Aurelio , Gutiérrez Ortega Ángel , Henríquez Jiménez Carlos , Romero Ramos Néstor , Portillo de Condoré Isabel
Published: May 2024

El presente estudio, tuvo como propósito, profundizar en los esquemas seculares sesgados y estereotipados, del imaginario sociocultural hispanoamericano. Durante su elaboración, se aplicó el diseño bibliográfico y método bibliográfico; la documentación fue la técnica aprovechada, e igualmente la matriz bibliográfica y la matriz analítica de contenido, fungieron como instrumentos investigativos. Con la discusión de los hallazgos alcanzados, pudo reconocerse que, durante más de dos siglos, la sociedad hispana ha atribuido al hombre blanco, un conglomerado de prerrogativas sui géneris; perpetuando así el anacronismo de la racialización, que persigue de manera sutil, sostener la segregación en algunos escenarios, donde el susodicho es quien teje los hilos del dinero y el poder. Finalmente, se logró generar una propuesta crítica, relacionada al valor que aún a inicios del siglo XXI, se le atribuye a la piel blanca en dicha región, como una suerte de huella indeleble del eurocentrismo, en su innegable colonización del pensamiento contemporáneo.
Coding Optimization for an Ecological non-linear Age-structured Fish Population Model with a Shepherd Recruitment Function
Authors: Erasmus Michelle M. , Makanda Gilbert
Published: May 2024

The study of the optimally density-regulated recruitment plays a crucial role in the overall management and determining of fishing efforts of marine fish populations. This paper will develop a Matlab code can determine what an optimal recruitment density regulation strategy would be for the un-fished population and what it changes to when fishing efforts are applied. This code can determine threshold values used to avoid fisheries from collapsing. The code will be applied to the Gulf of California Pacific sardine (Sardinops caeruleus) population. An age structured design with a Shepherd density regulating stock-recruitment function is used in this study. In this work, the parameter which is varied is captured in the Shepherd recruitment function and is associated with behavioral interventions such as selecting different drift routes and clumping on resources that will increase egg-larvae survival to the recruitment stage. A detailed background study of other models is explored, then a derivation of the Shepherd recruitment model is developed from the traditional discrete model. A special MATLAB code is then developed to illustrate the pair-wise invasive plots for the model structures. The code is for theoretical analysis of fish population models.
Concept-based Extension of SKOS Defense Controlled Vocabulary: Techniques and Implications
Authors: Giannaris Pericles S. , Doukas Nikolaos , Mastorakis Nikos
Published: May 2024

A controlled vocabulary is a set of terms that are utilized to represent knowledge in a domain. In the domain of defense, the use of terms such as “command, control, communications, computers, intelligence, surveillance and reconnaissance (C4ISR)”, “armored personnel carriers (APC)”, or “biological and bioinspired structures for multispectral surveillance” denote the core competencies of domain experts and the depth of diverse knowledge. This paper describes the second phase of the pilot project to create a defense-related controlled vocabulary with a focus on the Russo-Ukraine conflict. Applications for data annotation, SKOS hierarchical vocabulary development, and vocabulary quality analysis are used to identify terms in text, express identified terms in military press releases as SKOS vocabulary, and assess its structure. The preliminary vocabulary is extended by 173 concepts. The quality of the vocabulary is validated against a SKOS checker of twenty-four criteria.
Catalytic Activity Advancements in Organometallic Chemistry
Authors: Sikkander Abdul Mohamed
Published: May 2024

Organometallic chemistry is essential to catalysis and synthesis, helping to shape a wide range of chemical reactions. The study of the interactions between organic compounds and metal elements is known as organometallic chemistry. Modern synthetic chemistry and catalysis have been greatly influenced by the field of organometallic chemistry. It entails the investigation of substances that have metal-carbon bonds because they can have special catalytic and reactive qualities. Applications for these compounds are numerous and include materials science and pharmaceuticals. This multidisciplinary area of chemistry influences the development of many different chemical processes and has a significant impact on both catalysis and synthesis. Frequently used as catalysts in a variety of chemical reactions are organometallic compounds. For instance, transition metal catalysts can speed up reactions by offering a different, lower-activation-energy reaction pathway. Particularly transition metal catalysts, with their capacity to go through several oxidation states and form stable intermediates, are essential for catalyzing a variety of reactions. These catalysts can facilitate the synthesis of complex molecules that may be difficult to obtain through other means, as well as increase reaction rates and selectivity. Organometallic chemistry is still a dynamic field with many applications in different industries and continuous advancements. Selectivity is enhanced and reaction rates are raised as a result. For many industrial processes to be selective and efficient, catalysis is essential. In organic synthesis, organometallic compounds are useful reagents. They can perform a number of transformations that are difficult to accomplish with conventional organic reagents alone, including functionalizing organic molecules, forming and breaking carbon-carbon bonds, and engaging in other transformations. Consequently, the synthetic possibilities in organic chemistry have been greatly expanded by the field of organometallic chemistry. Organic synthesis has been transformed by the adaptability of organometallic compounds in creating and severing bonds as well as their capacity for a variety of transformations. Because of their exceptional reactivity and selectivity, they give chemists access to previously unattainable new molecular structures and compounds. This has significantly changed the field of organic chemistry by adding new tools to the toolbox and creating new opportunities for investigation and learning.
RELAKSASI BENSON MENINGKATKAN KUALITAS HIDUP PASIEN KANKER YANG MENJALANI KEMOTERAPI DI RSUD KRATON KABUPATEN PEKALONGAN
Authors: Umam Moh Khotibul
Published: May 2024

Efek samping kemoterapi pada pasien kanker tidak hanya menyebabkan masalah pada fisik saja, akan tetapi juga masalah psikis yang dapat menurunkan kualitas hidup pasien. Salah satu intervensi yang dapat dilakukan oleh perawat melalui pendekatan aspek psikis yaitu terapi relaksasi benson. Penelitian ini bertujuan untuk mengetahui pengaruh modifikasi terapi relaksasi benson terhadap kualitas hidup pasien kanker yang menjalani kemoterapi. Rancangan penelitian Pre-experiment without control group dengan one-group pre-post-test design melibatkan 30 responden dengan menggunakan uji statistik paired sample t-test. Instrumen EORTC QLQ C-30 digunakan untuk mengukur kualitas hidup. Hasil analisis statistik menunjukkan bahwa terdapat perbedaan skor rata-rata kualitas hidup pasien kanker yang menjalani kemoterapi sebelum dan sesudah pemberian modifikasi terapi relaksasi benson (p-value 0,0003 < 0,05). Mayoritas responden (90%) berjenis kelamin perempuan berusia >50 tahun (46,7%) dengan latar belakang pendidikan SD (40%). Perawat dapat mengaplikasikan terapi relaksasi ini di ruang perawatan pasien kanker dan mengajarkan kepada pasien dan keluarga. Selain itu, terapi ini juga masih dapat di kembangkan lebih lanjut dengan memberikan stimulasi lain seperti meditasi agar lebih efektif.
The side effects of chemotherapy among cancer patients not only impact physical problems but also psychological harm. These effects can reduce their quality of life. Therefore, a nursing intervention could be carried out through a spiritual approach such as modified Benson relaxation therapy. This study aims to identify the effect of modified Benson relaxation therapy on quality of life among cancer patients undergoing chemotherapy. A pre-experimental design with a one-group pre-post-test design was used, involving 30 patients. A paired sample t-test was used for the statistical test. The EORTC QLQ C-30 instrument was used to measure quality of life. The majority (90%) of respondents were female, aged >50 years old (46,7%), and their educational background was elementary school (40%). Statistical results showed that there was a difference in the average score of patient quality of life before and after being given therapy. Thus, modification of Benson relaxation therapy could improve the quality of life of cancer patients undergoing chemotherapy (p-value 0.0003 < 0.05). Nurses could teach and apply this therapy in cancer patient care rooms for the patients and their families. This therapy still needs to be developed further to make it more effective, such as when combined with meditation.
INDONESIAN NURSES CULTURAL COMPETENCE: THE DEVELOPMENT AND PILOT TESTING OF INSTRUMENT
Authors: Tappy Yunita Peggy
Published: May 2024

Introduction: This paper outlines the development and validation of the Indonesian Nurse's Cultural Competency Scale (IPNCCS) in response to the absence of such instrument for Indonesian nurses. Purpose: The aim was to create an instrument that accurately measures cultural competence among Indonesian nurses. Methods: The study followed a methodological approach in two phases, beginning with item generation through literature review, expert evaluation, and pilot testing with a sample of 50 Indonesian nurses. Result: Through item analysis, the scale's construct validity and reliability were established. The final scale comprises 46 items across five dimensions, showing strong internal consistency reliability (overall Cronbach’s alpha of .942, dimension Cronbach’s alpha ranging from .792 to .918), content validity, and construct validity. In conclusion, the INCCS offers a reliable and valid tool for assessing professional nurse competencies within diverse clinical settings in Indonesia.
KEYWORDS: Competence, Cultural competency, Indonesian nurse, Nursing, Reliability, Validity