bluuebunny/crossref_metadata_2025 huggingface dataset:
Idecabtagene vicleucel chimeric antigen receptor T-cell therapy for relapsed/refractory multiple myeloma with renal impairment
Authors: Sidana Surbhi , Peres Lauren C. , Hashmi Hamza , Hosoya Hitomi , Ferreri Christopher , Khouri Jack , Dima Danai , Atrash Shebli , Voorhees Peter , Simmons Gary , Sborov Douglas W. , Kalariya Nilesh , Hovanky Vanna , Bharadwaj Sushma , Miklos David , Wagner Charlotte , Kocoglu Mehmet H. , Kaur Gurbakhash , Davis James A. , Midha Shonali , Janakiram Murali , Freeman Ciara , Alsina Melissa , Locke Frederick , Gonzalez Rebecca , Lin Yi , McGuirk Joseph , Afrough Aimaz , Shune Leyla , Patel Krina K. , Hansen Doris K.
Published: September 2023

We evaluated patients with relapsed multiple myeloma with renal impairment (RI) treated with standard of care idecabtagene vicleucel (ide-cel), as outcomes with chimeric antigen receptor (CAR) T-cell therapy are unknown in this population. RI was defined as creatinine clearance (CrCl) <50 mL/min. CrCl of <30 mL/min or dialysis dependence were defined as severe RI. The study cohort included 214 patients, 28 (13%) patients with RI, including 11 patients severe RI (dialysis, N=1). Patients with RI were older, more likely to be female and had higher likelihood of having Revised International Staging System stage 3 disease. Rates and severity of cytokine release syndrome (89% vs. 84%, grade ≥3: 7% vs. 2%) and immune effector cell-associated neurotoxicity syndrome (23% vs. 20%) were similar in patients with and without RI, respectively. Patients with RI had higher incidence of short-term grade ≥3 cytopenias, although cytopenias were similar by 3 months following CAR T-cell therapy. Renal function did not worsen after CAR T-cell therapy in patients with RI. Response rates (93% vs. 82%) and survival outcomes (median progression-free survival: 9 vs. 8 months; P=0.26) were comparable in patients with and without RI, respectively. Treatment with ide-cel is feasible in patients with RI, with a comparable safety and efficacy profile as patients without RI, with notable exception of higher short-term high-grade cytopenias.
Vinculación universidad-entorno en el contexto de pandemia.
Authors: Álvarez Marisa , Grandoli María Eugenia , Xhardez Veronica
Published: September 2023

El trabajo presenta resultados de una investigación que analiza experiencias de colaboración y coproducción de conocimientos entre la universidad y su entorno. Estos procesos involucran dinámicas de interacción que implican estrategias de los protagonistas, experiencias previas y saberes, en un intercambio que implica modificaciones en las prácticas. La ponencia aborda el caso de una experiencia de vinculación, motivada en el contexto de emergencia por COVID-19, entre una universidad nacional, un centro tecnológico y una empresa privada, entre otros actores. Reconstruye el recorrido institucional, organizacional y sociotécnico para la producción de un ciclador respiratorio, analiza los factores claves que facilitan y obstaculizan su desarrollo, y busca definir las características de la coproducción de conocimientos en ese espacio de interacción. Como principal hallazgo se observa la incidencia de la excepcionalidad de l-a emergencia sanitaria en la ruptura con procesos tradicionales de vinculación universidad-entorno. Se destaca la amplia red de actores que se relacionan sin lazos previos, la colaboración y modificación de procesos burocráticos administrativos en tiempo récord, y cierta ruptura con la lógica tradicional de relación con el conocimiento entre universidad-entorno.
Las plataformas como infraestructuras. El uso del enfoque infraestructural para estudiar dos tipos de plataformas no digitales
Authors: Hubert Matthieu , Macedo María Guadalupe , Spivak L'Hoste Ana
Published: September 2023

Este artículo explora el concepto de plataforma desde un enfoque infraestructural, centrándose en su rol en la configuración y regulación de las actividades que habilita. Los resultados presentados se refieren a dos tipos de plataformas no digitales: primero, la Plataforma Escenarios Energéticos, una plataforma participativa que sirve para la formulación de proyecciones a futuro de una visión de la matriz energética y de su posible trayectoria futura; segundo, cuatro plataformas instrumentales en nanotecnología, que permiten compartir el acceso y el uso de una variedad de equipamientos e instrumentos destinados a la investigación y transferencia de tecnología en este campo. Consideramos sucesivamente los dos tipos de plataformas y los analizamos aplicando tres de los principios del enfoque infraestructural propuesto por Susan Leigh Star y Karen Ruhleder (2010). El enfoque infraestructural adoptado permite, en particular, analizar el proceso de coproducción entre las dimensiones técnicas y políticas de las plataformas estudiadas, subrayar el peso de sus inercias materiales e institucionales y mostrar los ajustes organizativos tal y como se producen, restituyendo las incertidumbres y los tanteos que conllevan.
Genotipos del virus del papiloma humano en citología alterada del cuello uterino
Authors: Zhingre Suárez Alicia Esperanza , Peñaloza Ullaguari María Isabel , Punina Quixpe Zonnia Maribel
Published: September 2023

Introducción: El Virus de papiloma humano pertenece a la familia Papillomaviridae, representa el 95% de los casos de cáncer cervical en todo el mundo, existen más de 200 genotipos de VPH incluyendo entre quince a diecinueve genotipos de VPH de alto riesgo, entre los más prevalentes tenemos el VPH 16, 18, 39, 58 y 31 que son responsables del desarrollo de cáncer de cuello uterino y los genotipos de VPH de bajo riesgo más prevalentes son el 6 y 11 que están implicados en el desarrollo de verrugas genitales. Objetivo: Identificar la presencia de los genotipos de virus de papiloma humano en citología alterada de cuello uterino. Metodología: Se realizó una revisión de tipo sistemática empleando el protocolo PRISMA para la recopilación de información en trabajos procedentes de motores de búsqueda como PubMed, ScienceDirect y Scopus buscando por genotipos de virus de papiloma humano en citología alterada del cuello uterino. Conclusión: Existe evidencia que demuestra la relación de los virus de papiloma de alto riesgo 16 y 18 seguidos de los 39, 58 y 31 que están involucrados en la transformación de las células cervicales. La infección por VPH desempeña un papel importante en el desarrollo de la neoplasia cervical siendo el principal factor de riesgo de esta patología. Sin embargo, el desarrollo de las vacunas contra el VPH puede reducir la carga de esta enfermedad, además, otro resultado revela que no existe vacuna para la infección causada para la infección por el genotipo 39 de HPV. Área de estudio general: medicina, Área de estudio específica: citología, Tipo de estudio: revisión bibliográfica.
Genotipificación del virus del papiloma humano y tipos de lesiones de cuello uterino en un hospital público de Durán
Authors: Moreira Pincay Marieta Stefania , Baldeón Miranda Eric Gonzalo , Arpi Alcívar Ana Belén , Loor Zambrano Julexy , Soasty Vera Rebeka
Published: September 2023

Introducción: actualmente una de las principales enfermedades que afecta a la población femenina a nivel mundial es el cáncer cervicouterino, donde el virus de papiloma humano (VPH) juega un papel central siendo una de las causas primarias que desencadenan esta patología. A pesar de que una cierta cantidad de mujeres cursa la enfermedad de forma asintomática e incluso pueden presentar citologías normales, es por medio del estudio genético de este virus que se determina el genotipo viral, así como los riesgos para desarrollar lesiones neoplásicas. Método: el presente estudio es cuantitativo, retrospectivo, transversal retrospectivo, diseño no experimental, método observacional, analítico y correlacional, cuyo objetivo fue establecer la correlación entre el genotipo viral del VPH con las lesiones intraepiteliales en cuello uterino en mujeres atendidas en la consulta externa de Ginecología del Hospital Básico Durán, en el periodo de enero del 2018 a octubre del 2021 con examen de citología cervical y genotipificación del VPH. Resultados: el trabajo incluyó a 100 pacientes que cumplieron con los criterios de selección, de las cuales el 55% fueron casos positivos y 45% casos negativos, de este porcentaje positivo los genotipos prevalentes fueron el 16 (14%), 51, 42 (8%), 35 y 54 (6%). Además, la citología revelo una mayor incidencia de lesiones intraepiteliales de bajo grado (53%) y lesiones intraepiteliales de alto grado (19%) donde los principales genotipos que afectaban a estas mujeres eran los de alto riesgo en ambas clasificaciones. Conclusiones: la genotipificación del VPH desempeña un rol muy importante para la orientación del médico con respecto a la evolución clínica de las pacientes, así como para un adecuado manejo de la enfermedad.
Several confirmed and probable zoonotic cases of toxigenic Corynebacterium ulcerans, Queensland, Australia
Authors: Slinko Vicki G , Guglielmino Christine JD , Uren Alexandra M , Smith James KG , Neucom Deborah , Smoll Nicolas R , Graham Rikki MA , Fang Ning-Xia , Smith Helen V , Armstrong Amanda E , Kenny Alison A , Farmer Janet L , Quagliotto Catherine A , Jennison Amy V
Published: September 2023

Background Toxigenic Corynebacterium ulcerans is an emerging zoonosis globally, causing both cutaneous and respiratory diphtheria-like illness. In Queensland, human infection with toxigenic C. ulcerans is rare, with only three cases reported before October 2015. This case series describes five subsequent cases of toxigenic C. ulcerans in Queensland with links to companion animals. Methods All data were collected as part of routine public health response, and strains were whole genome sequenced for further characterisation. Household contacts were screened, treated with appropriate antibiotics, and received a diphtheria toxoid-containing vaccine if more than five years had elapsed since their last dose. Findings No epidemiological or genomic links could be established between any of the five patients, including between the two cases notified from the same locality within eight days of each other. The C. ulcerans strains from Cases Two, Four and Five were closely related to the strains isolated from their respective pets by whole genome sequencing. Domestic dogs were identified as the most likely mode of transmission for Cases One and Three; however, this was unable to be laboratory confirmed, since Case One’s dog was treated with antibiotics before it could be tested, and Case Three’s dog was euthanised and cremated prior to case notification. Interpretation These are the first reported Australian cases of this emerging zoonosis with links to companion animals. These cases demonstrate the likely transmission route between companion animals and humans, with no evidence of human-to-human transmission. The existing requirement in the Queensland Health Public Health Management Guidelines, of restrictions on cases and some contacts while awaiting swab results, is currently under review.
First documented gymnasium cluster of COVID-19 with whole genome sequencing in Australia
Authors: Ravindran Bhavi , Gatens Elizabeth , Pal Naru , Sheppeard Vicky , Calik Anna , Alexander Kate , Ashraf Khizar , Arnott Alicia , Sintchenko Vitali , Dalton Craig B
Published: September 2023

Background Transmission of coronavirus disease 2019 (COVID-19) has been demonstrated in fitness settings internationally. We report the first documented case of transmission of COVID-19 in a gymnasium in Australia in 2020. Methods Case finding and case interviews were conducted among attendees in a Western Sydney gymnasium, Australia. Whole genome sequencing using an amplicon-based approach was performed on all SARS CoV-2 polymerase chain reaction positive samples detected through surveillance. Results We show that five cases of COVID-19 were linked to the gymnasium, with transmission occurring on 7 July 2020, when the index case transmitted the infection to four other gymnasium attendees through the sharing of an enclosed space. Conclusions There is an ongoing risk of transmission of COVID-19 within gymnasium environments and they are justifiably classified as a ‘high-risk’ venue. There may be a need to expand ventilation and space requirements to prevent transmission of COVID-19 in such settings in the context of severe COVID-19 variants or to prevent respiratory disease transmission in general.
The Need Analysis of Learning Module Development Using Self Organized Learning Environment (Sole) Assisted by Augmented Reality on Rotational Dynamics and Rigid Body Equilibrium
Authors: Rosniadi Pratama Oktaviyani , Connie Connie , Risdianto Eko
Published: September 2023

This study aims to analyze the need for the development of learning module using the Self Organized Learning Environment (SOLE) model assisted by Augmented Reality on rotational dynamics and rigid body equilibrium. This type of research is a survey research and literature study which later can be the basis for further development research. The research instrument used was a needs analysis questionnaire with 20 questions given to 72 respondents who were students and 3 respondents who were teachers of class XI MIPA from SMA Negeri 5 Bengkulu City, SMA Negeri 4 Bengkulu City and SMA Negeri 9 Bengkulu City. In this research the data analysis uses descriptive statistics. Based on the results of the data obtained it can be concluded that currently students are in dire need of computer-based learning media, one of which is by using Augmented Reality. This is based on data obtained that 76,26 % of students answered Strongly Agree and 77,92 % of teachers answered Strongly Agree to the need for the development of the development of learning module using the Self Organized Learning Environment (SOLE) model assisted by Augmented Reality on rotational dynamics and rigid body equilibrium.  We know that the development of digital technology in the current Industrial 4.0 era has brought changes and influenced various aspects of human life, including in the field of education. Augmented Reality are technologies that can be developed to provide alternative instructional media provided previously and to see the effectiveness of these media if used in learning activities.
The Role of “Penggerak” and Independent Principal as Manager
Authors: Widodo  , Sudarwan Danim  , Asti Putri Kartiwi
Published: September 2023

This study aims to determine the role of the principal regarding programming, organizing, activating and supervising at SMPN 21 Seluma and at SMPN 24 Kota Bengkulu. The research method used is descriptive qualitative, with research subjects being principals, teachers, administrative staff engineering data collection using interviews, observations, and documentation. Data analysis techniques by collecting data, analyzing data, presenting data, and drawing conclusions, and testing the validity of the data are carried out with credibility which includes triangulation, transferability, dependability and confirmability. Research shows that school principals plan detailed HR, policies, curriculum by involving teachers, committees. Organizing begins with compiling the school's organizational structure, division of competence. Mobilizing teachers and staff by providing directions and guidance, motivating employees to take part in training seminars, workshops, continuing studies and holding monthly evaluation meetings, supervision bymeans of; observing attendance discipline, learning process, seeking information through the school's deputy head and colleagues, and conducting supervision.
Impact of clinico-biochemical and inflammatory biomarkers on the immunogenicity and efficacy of SARS-CoV-2 adenoviral vaccine: a longitudinal study
Authors: Majid Sabhiya , Khan Mosin Saleem , Nisar Najila , Bhat Javid A , Haq Inaamul , Khan S Muhammad Salim
Published: September 2023

Purpose: Due to a lack of effective antiviral treatment, several vaccines have been put forth to curb SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection and to reduce the mortality and morbidity rate by eliciting a protective immune response, primarily through virus-neutralizing antibodies specific for SARS-CoV-2 spike protein. This longitudinal study was designed to evaluate the vaccine effectiveness and immune response following the administration of adenoviral vaccine, COVISHIELD, in Indian population who were previously uninfected with SARS-CoV-2 and to reveal the effect of various sociodemographic, inflammatory and biochemical factors on antibody response.
Methods: Briefly, the total immunoglobulin G (IgG) against SARS-CoV-2 spike and nucleocapsid protein along with the immunological markers were estimated by chemiluminescent microparticle immunoassay (CMIA) technology. Biochemical parameters were estimated by spectrometry.
Results: A total of 348 subjects received two doses of COVISHIELD (224 males, 124 females). The mean age of the study subjects was 42.03 ± 13.54 years. Although both the doses of COVISHIELD against SARS-CoV-2 spike protein induced a robust immune response that lasted for months in all the subjects, the total IgG titer against SARS-CoV-2 spike protein was found significantly higher in subjects ≥50 years of age, and those with obesity, elevated triglycerides and elevated lactate dehydrogenase levels.
Conclusions: There is a definite effect of age and biochemical factors on the immunogenicity of COVISHIELD. An understanding of these factors could not only impact the design of vaccines and help improve vaccine immunogenicity and efficacy but also assist in decisions on vaccination schedules, in order to combat this deadly pandemic.
Microscopia en cuero vacuno con pelo y cuero vacuno depilado
Authors: Esterelles Mariana Sandra , Cachile Adriana Marcela
Published: September 2023

El objetivo de este trabajo es obtener patrones de imágenes de cuero vacuno con pelo y depilado que permitan observar su estructura mediante técnicas histológicas, con la contribución fundamental de una lupa binocular, un microscopio óptico y un microscopio de barrido (SEM). Como resultado, se espera ampliar el conocimiento y la comprensión de la estructura del cuero vacuno a través de imágenes.
Extent of Knowledge and Application the Basics of Biomechanics Among Paralympic Games Coaches
Authors: Alkhawaldeh Ibtehal , Alzughialat Mohannad
Published: September 2023

This study aimed to identify the extent to which the bio-mechanical principles of human movement are known and applied in training the skill aspects of Paralympic coaches where the sample of the study consisted of 35 Paralympic coaches from several countries, all of whom are males. The average age of 42 ± 3.4 years. Their average training age was 7.5 ± 2.6 years. In order to achieve the study's objectives, the researchers designed a cognitive test that its validity, reliability, difficulty index were confirmed, and composed of 51 questions distributed to 6 axes. They also designed a questionnaire that its validity and reliability were confirmed and consistent and made up of (38) A paragraph distributed to (6) axes. The study results showed a low level of knowledge and low degree of application of the basics of biomechanics among Paralympic coaches. According to the results of our study, The responsible authorities of the Paralympic Committees should provide their coaches with special courses in biomechanical analysis and enhance their capabilities in this field, given its practical importance.. Academic agencies that issue training certificates in the field of sports training for persons with disabilities should focus on the field of biomechanical analysis and its related matters in their teaching programs.
Unstable Periodic Homotopy Theory
Authors:   , Shi Yuqing
Published: September 2023

In this thesis we study unstable vₕ-periodic homotopy theory, where h is a natural number; here ``unstable'' refers to the homotopy theory of topological spaces. The work consists of two parts. In Part I we give a detailed exposition of the foundations of unstable vₕ-periodic homotopy theory, sharpen an existing result about vₕ-periodic equivalences of H-spaces, and pose concrete questions and conjectures for future studies. The expository part follows paper by Bousfield, Dror Farjoun and Heuts and aims to assemble in one place the central notions and theorems of unstable localisations with a focus on unstable periodic homotopy theory. The goal of Part II is to understand unstable vₕ-periodic phenomena from the point of view of Lie algebras in the stable vₕ-periodic homotopy category. We analyse the costabilisation of vₕ-periodic homotopy types and obtain a universal property of the Bousfield--Kuhn functor.
SOSIALISASI OLAHRAGA TRADISIONAL HADANG DI DESA KARANGHARJA
Authors: Arif Zainal Mustofa , Lasma Yunita , Maysaroh Chairunnisa Nurlaila
Published: September 2023

The traditional game of hadang is a form of game that is popular in Indonesia, especially in Karangharja Village. However, now this game is starting to be forgotten and is no longer practiced by the community. The purpose of this community service activity is to introduce the traditional hadang game by way of socialization back to the people of Karangharja Village and increasing public interest in playing it. The method used in this study is the method of socialization and training. The results of the socialization activities showed that the people of Karangharja Village, Pebayuran District, had a high interest in playing the traditional Hadang game. It is hoped that this sport can be enjoyed by the people of Karangharja village and one day it will become a sport that is enjoyed by the people of Karangharja village. Hadang is a traditional Indonesian sport to improve the fitness and physical quality of the people of Karangharja Village. Presumably "Hadang" can also be an alternative sport. Hadang is a game that contains skill values and increases self-confidence and improves concentration. Increasing participants' interest in traditional obstacle sports.
PEMANFAATAN SEKAM PADI MENJADI BRIKET SEDERHANA SEBAGAI ENERGI ALTERNATIF DI DESA KARANGREJA
Authors: Ilyasa Kefin Firas , Paryati Ninik , Maysaroh Chairunnisa Nurlaila
Published: September 2023

As one of the villages with sufficient rice yields to be a mainstay of local residents, Karangreja Village is still unable to manage rice husk waste optimally. One example of an easy and energy efficient form of husk waste management is by making charcoal briquettes from rice husks as fuel. Making rice husk charcoal briquettes provides more advantages than charcoal such as being more economical, clean and easy to pack. Furthermore, the use of rice husk charcoal briquettes can be a solution to current global problems related to pollution, alternative energy and environmentally friendly technologies. The purpose of the service activity is to utilize rice husk waste to become briquettes as an alternative energy with the method of implementing the service using the training method. The results of the activity have a significant impact in the form of knowledge for Karangreja Village residents, especially farmers, reduction of agricultural waste, and as an opportunity to increase farmers' welfare through the sale of rice husks as raw material for briquettes
PENGEMBANGAN KREATIFITAS WARGA DALAM MENDAUR ULANG SEDOTAN MENJADI KINCIR-KINCIR
Authors: Mardiana Novi , Siaga Pangestuti Rinda , Rusham Rusham
Published: September 2023

Garbage in general can be interpreted as waste material that people don't like and don't want, where most of it is material or residue that is no longer used and will cause disruption to public health and the environment. The definition of waste is waste is the remains of human daily activities and/or natural processes in solid form." In other words, waste is a solid or semi-solid substance that is wasted or is no longer useful, either decomposing or non-decomposing, except for waste solids or human waste. Thus, waste can be interpreted as unwanted objects in solid form as a result of human activities that economically have no value or have no benefits. Processing waste into creative products. Managing waste is a sense of concern for the environment. In addition, processing waste into creative products will motivate people to participate in utilizing waste. Of course, the enthusiasm of the people is an added value in the economy
PERFORMANCE OF SMALL SIZE AEROSPIKE. ENGINE
Authors: Aithani Sanjay Singh , Shahid Abdulla , Shaikh Amir Nadeem
Published: September 2023

In this paper we are showing how aerospike nozzle can play an important role in rocket INDUSTRY as compare to other nozzles. We are using New rocket designs and increasing the performance of the current rockets But, the aerospike nozzle concept that has been under development since the 1950s is yet to be utilized on a launching. Due to its ability to adjust the environment by altering the outer jet boundary, the aerospike nozzle has better performance compared to present day others nozzle. An aerospike nozzle is designed for 20 bar pressure ratio to improve the performance of the aerospike nozzle for various conditions, some important design parameters and their performances were studied for low temperature flow conditions.
Root Cause Analysis of Patient Samples Rejected by Laboratories: 21-Step Application Example
Authors: ARSLAN Büşra , ŞAHİN Dilek
Published: September 2023

Aim: Root cause analysis is widely used in healthcare services to analyze the causes of near misses and adverse events with a systematic approach. This study, it is aimed to determine the root causes of rejected samples, define corrective/preventive actions, and create an action plan that will help the implementation of the suggested remedial actions and evaluate their effectiveness.

Material and Methods: For the 21-step methodology, observation, interview, document and record review techniques were applied. The steps of the process were visualized with the flowchart technique and the reasons for rejected samples were analyzed with team members. The identified causes were visualized with the Fishbone Diagram technique, and the risk reduction strategies and improvement actions for rejected samples were determined by the Failure Mode Effect Analysis (FMEA) method. The Action Hierarchy tool was used to evaluate the power of improvement actions.

Results: The root causes of rejected samples were identified as inadequate orientation and training practices, lack of applicability of policies and procedures, lack of monitoring and evaluation, inefficient process flow and lack of equipment. A total of 11 improvement actions were determined and planned for these root causes. It was predicted that there will be an approximately 64.5% decrease in risk scores in general with the basic measures presented in the performed FMEA.

Conclusion: Overall, it was found that the 21-step methodology is suitable for determining root causes by offering detailed guidance.
Çocuklar Açısından Ev Ortamındaki Obezojenik Faktörler ve Ebeveynler ile Çocuğun Yeme Alışkanlıkları Arasındaki İlişki
Authors: ERDİM Leyla , ERGÜN Ayşe
Published: September 2023

Amaç: Ailelerin beslenme alışkanlıklarının çocukluk obezitesine katkısının olduğu gösterilmiştir. Bu nedenle çocuklar ve ebeveynlerinin yeme davranışlarının birlikte incelenmesi önemlidir. Çalışma çocuklar açısından ev ortamındaki obezojenik faktörleri ve ebeveynler ile çocuğun yeme alışkanlıkları arasındaki ilişkiyi belirlemek amacıyla yapıldı.

Gereç ve Yöntemler: Çalışma Eylül-Aralık 2018 tarihleri arasında iki ilkokul ve iki ortaokulda eğitim gören 1235 çocuk ve ebeveynleri ile yapılmış ilişki arayıcı tipte bir araştırmadır. Çalışma verileri, çocukların ebeveynlerinden “Çocuk-Ebeveyn Bilgi Formu” ve “Aile Beslenme Alışkanlıkları Soru Formu” ile toplandı.

Bulgular: Çalışmada çocukların %13,7’sinin fazla kilolu, %17,6'sının obez olduğu belirlendi. Ebeveynlerin belirttiğine göre “salon/oturma odasında yemek” ve “televizyon izlerken, okurken, çalışırken yemek” anne, baba ve çocuk arasında en sık paylaşılan beslenme alışkanlıklarıdır. Ailelerin evlerindeki tuzlu ve tatlı atıştırmalık sayısı 0 ile 10 arasında değişmektedir ve ebeveynlerin %42,6’sı bu yiyecekleri kolay ulaşılabilen yerlerde bulundurmaktadır. Çocukların %47,8’i ebeveynlerinden izinsiz bazen tatlı ve tuzlu atıştırmalık tüketmektedir. Anne, baba ve çocuğun yeme alışkanlıkları arasında maddeye göre değişen orta veya düşük düzeyde pozitif korelasyon bulundu (p0.05).

Sonuç: Çalışmaya katılan ailelerin ev ortamı obezojenik yiyecekler bakımından zengindir. Ebeveynler ile çocuklarının obeziteye katkı sağlayacak şekilde benzer yeme alışkanlıkları vardır. Aile tabanlı obezite önleme programlarında çocukların ve ebeveynlerinin yeme alışkanlıklarının birlikte ele alması sağlıklı beslenme davranışının geliştirilmesinde etkili olacaktır.
Bir Üniversite Hastanesinde Mavi Kod Uygulamasına Bakış: Ne Kadar Gerçekçiyiz, Neler Yapmalıyız?
Authors: AKBUDAK İlknur Hatice , ERDOĞAN Çağla
Published: September 2023

Amaç: Bu çalışmanın amacı; mavi kod uygulamasının önemi, etkinlik ve güvenilirliğine dikkat çekmek, işleyişteki aksaklıklar, sorunlar ve bunlarla ilgili çözüm önerilerini paylaşmaktır.

Gereç ve Yöntemler: 2018-2022 yıllarında Mavi Kod Bildirim Formları (MKBF) retrospektif olarak incelendi. Yaş, cinsiyet, çağrının verildiği birim, çağrının verildiği saat ve zaman dilimi, ekibin ulaşma zamanı, olası nedenler ve uygulama sonuçları değerlendirildi

Bulgular: Kayıtlara geçen 192 mavi kod çağrısının (MKÇ) 86’sı (%44,8) kadın, 106’sı (%55,2) erkek, yaş ortalaması 53,23 olarak saptandı. Müdahale yeri oranlarına bakıldığında en büyük oranın hastane koridorları ve bekleme salonları olduğu görüldü. Öğleden önce ve öğleden sonra olan çağrılarda sayısal açıdan istatistiksel olarak anlamlı bir fark görülmedi. Ekiplerin %70 oranında 1 dakikadan kısa sürede çağrı noktasına ulaştığı gözlendi. Olay yerinde konan ön tanılara bakıldığında senkop ilk sırada yer aldı. Çağrıların ileri yaşam desteği gerektiren durumlarına bakıldığında; 51 çağrının resüsitasyon gerektirdiği, diğer çağrıların basit tıbbi müdahale ile yönetilebilir olduğu görüldü. Müdahale yerlerinde MKÇ’nin gerçek olması ve resüsitasyon ihtiyacı ilişkisine bakıldığında işlem ünitelerindeki çağrıların mavi kod olma olasılığının belirgin yüksek olduğu (p
A Bibliometric Analysis Study on Bone Marrow Transplantation Research Originating from Turkey
Authors: ÖZLÜ Can , ALKAN Sevil
Published: September 2023

Aim: Scientific publications serve as indicators of global interest and activity in research. The aim of this study was to describe the characteristics of the scientific literature on bone marrow transplantation in Turkey between 1990 and 2022.

Material and Methods: In this bibliometric study, we searched the Web of Science database for all biomedical articles published between 1990 and 2022. MESH terms related to "Bone marrow transplantation" were used as the search keyword. The search was then narrowed by selecting Turkey as the country of publication. All data were transferred from the relevant database to Vosviewer and biblioshiny programs and analyzed.

Results: A total of 121 countries contributed to the bone marrow transplant literature with 41,236 publications. Turkey ranked 13th with 913 publications (2.214%). and 402 articles by 2991 authors from Turkey. This corresponded to 0.305 publications per author. These publications received 6.183 citations per publication. After 2014, the number of publications increased. Most articles (n=123) were published in 2015. In 2016, the number of publications decreased by almost half after the first peak and did not fall below 50 publications/per year in the following years. Ankara University (n=207), Hacettepe University (n=166), Gazi University (n=95), Erciyes University (n=82), and Akdeniz University (n=79) were the institutions that published the most publications on bone marrow transplantation.

Conclusion: Bone marrow transplantation appears to be of interest to Turkish researchers; however, not to the expected level. Turkey continues to lag behind other countries in this field despite an increase in research activity pertaining to bone marrow transplants in recent years.
Eczacıların Empati Düzeyleri Üzerine Bir Çalışma
Authors: ULUTAŞ DENİZ Elif , KÖKSAL Ganime İrem , EREN Rumeysa
Published: September 2023

Amaç: Literatürde, eczacıların empati becerilerinin değerlendirildiği çok az çalışma bulunmaktadır. Türkiye’de ise eczacılarda empati becerilerine yönelik herhangi bir çalışmaya rastlanılmamıştır. Bu çalışma Erzurum ilinde mesleğini icra eden eczacıların empati seviyelerini değerlendirme amacı ile yapılmıştır.

Gereç ve Yöntemler: Veri toplamada sosyo-demografik veri formu ve Empati Ölçeği (EÖ) kullanılmıştır. Baron-Cohen ve Wheelwright tarafından geliştirilmiş, Baysan-Arabacı ve Bora tarafından Türkçe geçerlilik-güvenirliliği yapılmıştır. 60 maddeden oluşan ve 4’lü likert derecelendirme tipinde olan ölçeğin iç güvenirlik katsayısı 0,85 olarak hesaplanmıştır. Anket formu Google Forms üzerinden hazırlanarak hedef kişilere gönderilmiştir. Anketi cevaplamayı gönüllü olarak kabul eden 74 eczacı ile uygulama gerçekleştirilmiştir.

Bulgular: Genel olarak eczacıların empati puanlarının (49,26±12,33) ortalamanın üstünde olduğu saptanmıştır. Çalışma alanı, öğrenim durumu, meslekte geçirilen yıl sayısı ve yaş değişkenlerine göre yapılan tek yönlü varyans analizi (ANOVA) sonuçlarına göre; çalışma alanı ve empati arasında istatiksel olarak anlamlı farklılık gözlenirken (p=0,036); öğrenim durumu, meslekte geçirilen yıl sayısı, yaş ve empati arasında istatiksel olarak anlamlı farklılık gözlenmemiştir (sırasıyla p=0,172; p=0,532; p=0,541). Cinsiyet, medeni durum, mesleğini gönüllü tercih etme durumu değişkenlerine göre yapılan t testi sonuçlarına göre, empati puanları ve cinsiyet arasında istatiksel olarak anlamlı farklılık gözlenirken (p=0,041); medeni durum, mesleğini gönüllü tercih etme durumu ve empati arasında istatiksel olarak anlamlı farklılık gözlenmemiştir.

Sonuç: Empatinin iletişim becerileri üzerindeki etkisi göz önüne alındığında; bu yeteneğin arttırılması, sağlık çıktılarının optimal seviyelere ulaşmasını sağlayacaktır. Eczacıların empatisini geliştirmek için sürekli ve devam eden eğitimlerin yanı sıra eczacılık eğitiminde psikodrama, rol alma ve rol model tekniklerinin kullanıldığı empati kurslarının/derslerinin eklenmesi önerilebilir.
Resistance Rates of Streptococcus agalactiae Strains Isolated from Urine Samples to Various Antibiotics
Authors: AYGAR İsmail Selçuk
Published: September 2023

Aim: Group B Streptococcus (GBS), also known as Streptococcus agalactiae, are Gram-positive, encapsulated bacteria found in the normal human gastrointestinal and urogenital flora. A wide variety of infectious diseases can cause urogenital system infections in newborns, elderly people, immunocompromised people, pregnant women, and adults. In this study, we aimed to inform clinicians about the agents that can be used in intrapartum antibiotic prophylaxis by examining the antibiotic susceptibility of GBS strains isolated from urine samples from the Gynecology and Obstetrics Clinic in our laboratory.

Material and Methods: Isolates of the S. agalactiae isolated from a total of 222 urine samples from the Gynecology and Obstetrics Clinic that came to our Medical Microbiology laboratory between January 2022 and December 2022 were included and the data of these isolates were evaluated retrospectively. The clinical samples that came to our laboratory were inoculated on Sheep blood agar medium and incubated at 37°C for 18-24 hours. Quantitatively seeded urine culture ≥104 CFU/ml grown bacteria was considered a uropathogenic. Urogenital skin flora element or three and more different types of bacteria growing cultures as contamination evaluated.

Results: Due to the group selected as the sample, 100% of the patients were female. The age range of the patients ranged from 12 to 72, and the mean age was calculated as 30.16. All GBS isolates were susceptible to penicillin, linezolid, trimethoprim-sulfamethoxazole, tigecycline, teicoplanin, and vancomycin.

Conclusion: Penicillin resistance was not found in our study. However, resistant strains were detected in erythromycin, clindamycin, and levofloxacin, which stand out as other options in cases where penicillin cannot be used.
Studi Fenomenologi: Proses Self disclosure Akun Pseudonim di Twitter
Authors: Cahyani Intan Putri , Syaikhah Hanifah
Published: September 2023

Era cyberculture memungkinkan berbagai jenis akun bermunculan di media sosial, termasuk akun pseudonim di Twitter. Memiliki konsep yang berbeda dengan media sosial lain, Twitter menjadi tempat para pengguna akun pseudonim untuk leluasa bercerita dan mengekpresikan diri melalui pengungkapan diri tanpa takut mendapatkan social judgement karena yang digunakan bukanlah identitas asli. Riset ini bertujuan untuk mengkaji dan menganalisis pengalaman pengguna akun pseudonim di Twitter dalam melakukan pengungkapan diri.. Riset ini merupakan studi deksriptif kualitatif dengan menggunakan metode fenomenologi. Sebanyak tujuh orang informan dilibatkan dalam wawancara mendalam yang digunakan sebagai sumber data primer penelitian. Penelitian ini menunjukkan bahwa Proses Self disclosure yang terjadi melalui akun pseudonim Twitter berawal dari adanya hambatan komunikasi yang terjadi di kehidupan nyata yang menyebabkan para pengguna memutuskan untuk menggunakan akun pseudonim sebagai tempat pengguna mengungkapkan dirinya. Adanya ketertarikan yang sama antar pengguna akun pseudonim yang kemudian dijadikan sebagai bahan untuk berinteraksi dan berkomunikasi satu sama lain. Proses self-disclosure dimulai dengan keputusan pengguna untuk membuka diri dan berbagi cerita pribadi serta mengungkapkan emosi kepada sesama pengguna akun pseudonim. Tingkat keterbukaan diri ini menjadi penentu keberlanjutan hubungan antara mereka. Dalam aktivitas pengguna akun pseudonim, terdapat tiga pola self-disclosure. Pola pertama adalah pengungkapan diri melalui cuitan tweet tanpa ditujukan kepada siapapun. Pola kedua adalah self-disclosure dengan adanya feedback melalui reply section atau melalui pesan langsung. Pola ketiga adalah pola komunikasi banyak arah melalui interaksi dengan beberapa orang melalui tweet atau grup pesan langsung.Kata Kunci: Akun pseudonim; Fenomenologi;  Pengalaman pengguna; Pengungkapan diri; Twitter
Taktik Media Mendulang Clickers melalui Teknik Clickbait
Authors: Taufik Cevi Mochamad , Suhaeri Suhaeri , Lusiawati Ira
Published: September 2023

Clickers berperan dalam sistem operasionalisasi media yang bergerak di jaringan internet. Kehadirannya sangat menentukan bagi tumbuh atau gagalnya media online. Dalam perkembangannya, dengan semakin banyak pengguna internet secara otomatis mengubah peran clickers, dari semula hanya sebagai pembaca selanjutnya menjadi pasar dan target potensial dalam penyebaran berita. Untuk menarik jumlah khalayak yang mengeklik satu item berita saja, media berstrategi dengan menggunakan teknik clickbait. Teknik ini digunakan untuk menumbuhkan perhatian dan keingintahuan khalayak terhadap konten yang ditebarkan media online sehingga terdorong mengeklik dan membaca secara keseluruhan. Namun clickers kerap kecewa karena clickbait yang digunakan media tidak sesuai dengan naskah yang diterangkan. Berdasarkan latar belakang tersebut, penelitian ini bertujuan untuk mengetahui teknik clickbait yang digunakan media online dalam suasana ketika khalayak sudah memahami teknik tersebut. Selanjutnya, metode yang digunakan dalam penelitian ini adalah metode kualitatif dengan tipe analisis konten media online. Hasil penelitian menunjukkan bahwa tekni clickbait digunakan media kredibel sebagai bagian dari strategi untuk meningkatkan minat pembaca. Teknik ini juga digunakan sebagai salah satu sarana survive bagi media agar dapat secara kontinu melayani kebutuhan informasi khalayak.Kata Kunci: Clickbait; Clickers; Khalayak; Media; Online
Strategi Komunikasi Public Relations Dalam Membangun Citra Perusahaan Summertide Melalui Perubahan Kemasan Ramah Lingkungan
Authors: Rahmawati Suci , Andrini Susi
Published: September 2023

Sampah plastik masih menjadi salah satu masalah yang sulit diatasi, sehingga menyebabkan sebagian masyarakat mulai beralih ke produk yang memiliki tanggung jawab lingkungan. Salah satu perusahaan yang concern dengan masalah lingkungan ialah Summertide, Summertide merupakan perusahaan di bidang retail baju renang anak. Tujuan penelitian ini adalah untuk mengetahui Bagaimana Strategi Komunikasi Public Relations yang dilakukan Summertide Dalam Membangun Citra Perusahaan Melalui Perubahan Kemasan Ramah Lingkungan. Konsep yang dipakai pada penelitian ini dengan menggunakan konsep strategi Public Relations dari Cutlip, Center dan Broom, dengan empat tahapan meliputi; mendefinisikan masalah. perencanaan dan pemrograman, pengambilan keputusan dan evaluasi. Pendekatan yang digunakan dalam penelitian ini adalah kualitatif dengan jenis penelitian kualitatif deskriptif. Untuk pengumpulan data dilakukan dengan cara observasi, wawancara secara mendalam dan dokumentasi. Sedangkan teknis untuk menganalisis data melalui beberapa tahapan yakni dengan reduksi data, penyajian data dan verifikasi serta simpulan. Hasil penelitian menunjukan bahwa empat tahapan oleh Cutlip, Center dan Broom dengan dengan tahapan mendefinisikan masalah, perencanaan dan pemrograman dengan melakukan perubahan kemasan dari bahan plastik dengan jenis Polivinicl Klorida (PVC) yang tidak ramah lingkungan ke bahan oxo-biodegradable yang ramah lingkungan. Dilanjutkan dengan tahapan mengambil tindakan dan berkomunikasi dengan strategi secara online dan offline serta evaluasi sehingga didapatkan hasil temuan bahwa bertambahnya respon positif dari konsumen dan adanya peningkatan jumlah penjualan yang signifikan. Dengan demikian setiap tahapan mendukung penelitian ini dalam membangun citra positif perusahaan melalui perubahan pada kemasan.Kata Kunci: Citra; Kemasan Ramah Lingkungan; Komunikasi; Public Relations; Strategi
Effects of Common In-Service Defects of Different Insulators on Radio Frequency Interference Emission from 765 kV Insulators String
Authors: Rajamani P. , Rao K. Devender , Nirgude Pradeep M.
Published: September 2023

Worldwide utilities are preferring Ultra-High Voltage (UHV) transmission lines for transmitting electric power from generating stations to load centres. This long-distance UHV transmission line uses porcelain, glass and composite insulators. Fault-free operation of these insulators is vital to provide reliable service to consumers. Any defects on these insulators may lead to outages and affect the reliability of the supply system. To ensure reliability, utilities are continuously monitoring the condition of transmission line insulators. Nowadays in addition to providing reliable and quality power to the consumers, the utilities are keen on measuring and reducing The Radio Frequency Interference (RFI) from transmission lines. Under normal operating conditions, the RFI of the insulator string may be less than the specified limit. However, evolving inservice defects and deposition of pollutants on the surface of the insulator may increase the RFI level, sometimes it may exceed the specified limit also. This higher emission may affect the operation of nearby other electronic equipment. In this present work, an attempt is made to measure and compare RFI from healthy and defective 765 kV single I suspension string in the shielded indoor laboratory. It was observed that defects and pollutants deposited on insulators have induced corona/spark or gap discharges at the operating voltage level, which in turn increases the intensity of RFI.
Experience Open to Interpretation: US Presidents and Economic Coercion
Authors: Walentek Dawid
Published: September 2023

We assume that the motivation for the use of economic sanctions is rooted in the ambition of the policy-makers to change the behaviour of a target state. Yet, given the low effectiveness of sanctions, scholars suggest that sanctions are imposed to address the expectations of the domestic audience and the motivation is symbolic. I test the symbolic argument, look for the presence of an audience benefit for an imposition of sanctions and an audience cost for issuing of an empty threat and investigate potential confirmation bias among US presidents. I find no evidence for higher popularity following an imposition of sanctions, nor lower popularity after an empty threat. However, I do observe that US president are more likely to follow up on a threat of sanctions if they experienced a spell of lower approval ratings. US presidents do play at the home crowd with sanctions, but the crowd is indifferent.
STRATEGI PEMANFAATAN MEDIA SOSIAL DALAM MENINGKATKAN BRAND IMAGE PANTAI GLORYMELUR
Authors: Jundi Irwan Maulana Jundi , Sholihul Abidin Sholihul Abidin
Published: September 2023

Instagram is a social media used by the Glory Beach management to refer information and improve branding. The formulation of the problem of this research is how to use Glory Beach Instagram, and how to increase the Glory Beach brand image through Instagram. This research uses a descriptive qualitative research approach (descriptive research). The conclusions in this study indicate that the strategy for increasing the Brand Image of tourism places in the @GloryMelur account is carried out by implementing branding strategy steps which include determining the target market, determining existing competition, determining the point of difference (DOP). Categories of content posted by the @GloryMelur account include promos, posters, job vacancy information, events, holiday greetings, visitor activities and views. The implementation of the branding strategy carried out by the @GloryMelur account can be seen in the categories of posts uploaded. Determining the target market is more targeted by posting promos and events. Determination of competition can be seen through posting promos and events that are not carried out by other similar tourism accounts (comparison with the @vio-vio account), as well as points of difference (DOP) in posting @GloryMelur content, namely content about promos, posters, job vacancy info, events, holiday greetings.

 

Keywords: brand image, media sosial, tourism, instagram
ANALISIS YURIDIS UNDANG-UNDANG NOMOR 30 TAHUN 1999 TERHADAP PENYELESAIAN SENGKETA KREDIT PERBANKAN DI BIDANG KEPEMILIKAN RUMAH
Authors: Debora br situmeang Erni
Published: September 2023

Home Ownership Credit, known as KPR, is a banking product in credit, which is currently still regulated in Regulation Number 10 of 1998 concerning Changes to Regulation Number 7 of 1992 concerning Banking or alluded to as the Financial Regulation. In granting housing loans, creditors also sometimes find problems that there are debtors who default, resulting in bad credit. The targets of this study are: To start with, to figure out the gatherings who have privileges and commitments in the House purchasing Credit Arrangement at Bank Maybank Batam; Second, to figure out the reasons for terrible credit on contracts at Bank Maybank Batam, Third, to figure out ways of settling awful advances on contracts utilized by Bank Maybank Batam. The examination technique that specialists use in this kind of exploration is experimental juridical. The data collection technique used was in the form of direct interviews with informants from the Maybank Bank Batam Main Branch Office located in Jodoh. Furthermore, to complete the information from the informants, the researchers asked customers to provide answers to the questions given in the form of questionnaires. The research results that can be described in this paper are: First, the parties who make credit are called: debtors and creditors and they also have rights and obligations; Second, the occurrence of bad credit experienced by Bank Maybank Batam can be seen based on 2 (two) factors, namely: a. the internal factor that causes bad credit is the weak credit administration and supervisory system, b. weak bad credit information system. In addition, external factors that cause bad credit are disappointment of the indebted person's business, debacle for the debt holder or the borrower's business activities in credit settlement.

Keywords : Banks; Credit agreement; House; Ownership Credit.