bluuebunny/crossref_metadata_2025 huggingface dataset:
Genome-Wide Identification of the Cytochrome P450 Superfamily Genes and Targeted Editing of BnCYP704B1 Confers Male Sterility in Rapeseed
Authors: Wang Zhilai , Zhang Yanfeng , Song Min , Tang Xiuhua , Huang Shuhua , Linhu Bin , Jin Ping , Guo Weike , Li Fang , Xing Liwen , An Ran , Zhou Xiaona , Hao Wenfang , Mu Jianxin , Xie Changgen
Published: January 2023

The cytochrome P450 (CYP450) monooxygenase superfamily, which is involved in the biosynthesis pathways of many primary and secondary metabolites, plays prominent roles in plant growth and development. However, systemic information about CYP450s in Brassica napus (BnCYP450) was previously undiscovered and their biological significance are far from understood. Members of clan 86 CYP450s, such as CYP704Bs, are essential for the formation of pollen exine in plant male reproduction, and the targeted mutagenesis of CYP704B genes has been used to create new male sterile lines in many crops. In the present study, a total of 687 BnCYP450 genes were identified in Brassica napus cultivar “Zhongshuang 11” (ZS11), which has nearly 2.8-fold as many CYP450 members as in Arabidopsis thaliana. It is rationally estimated since Brassica napus is a tetraploid oil plant with a larger genome compared with Arabidopsis thaliana. The BnCYP450 genes were divided into 47 subfamilies and clustered into nine clans. Phylogenetic relationship analysis reveals that CYP86 clan consists of four subfamilies and 109 BnCYP450s. Members of CYP86 clan genes display specific expression profiles in different tissues and in response to ABA and abiotic stresses. Two BnCYP450s within the CYP704 subfamily from CYP86 clan, BnCYP704B1a and BnCYP704B1b, display high similarity to MS26 (Male Sterility 26, also known as CYP704B1). These two BnCYP704B1 genes were specifically expressed in young buds. We then simultaneously knocked-out these two BnCYP704B1 genes through a clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) genome engineering system. The edited plants displayed a pollenless, sterile phenotype in mature anthers, suggesting that we successfully reproduced genic male sterility (GMS, also known as nuclear male sterility) lines in Brassica napus. This study provides a systemic view of BnCYP450s and offers a strategy to facilitate the commercial utility of the CRISPR/Cas9 system for the rapid generation of GMS in rapeseed via knocking-out GMS controlling genes.
Assessment of PCDD/Fs Emission during Industrial-Organic-Solid-Waste Incineration Process in a Fluidized-Bed Incinerator
Authors: Ying Yuxuan , Wang Xiaoxiao , Song Wenlong , Ma Yunfeng , Yu Hong , Lin Xiaoqing , Lu Shengyong , Li Xiaodong , Huang Wei , Zhong Li
Published: January 2023

This study was conducted in a fluidized-bed incineration plant, evaluating the formation, emission and flux of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) from industrial-organic-solid-waste (IW) incineration. The results revealed that both the total (or I-TEQ) concentrations of toxic and 136 total PCDD/Fs in flue gas (FG), fly ash (FA) and bottom ash (BA)were ramped up to a higher level than those during municipal-solid-waste (MSW) incineration. A possible explanation was the chlorine (Cl) content of IW. However, the emitted PCDD/Fs in FG (FA/BA) still fulfilled the criteria. Subsequently, similar distribution patterns of PCDD/F isomers were observed in subsystems, indicating a unified formation-pathway. De novo synthesis was detected as the dominant formation-pathway of PCDD/Fs, while high-temperature and precursor syntheses were excluded. DD/DF chlorination formed PCDD/Fs to some extent. Furthermore, the mass flow chart indicated that PCDD/Fs output in primary FG was significantly strengthened (>1000 times) by de novo synthesis, from 1.25 μg I-TEQ/h to 1.67 mg I-TEQ/h. With effective cleaning by APCS, 99.6% of PCDD/Fs in FG were purified. PCDD/Fs in the gas phase were finally emitted at a discharge rate of 7.25 μg I-TEQ/h. However, accumulated FA took most PCDD/Fs into the environment (>99%), reaching 3.56 mg I-TEQ/h.
High Molecular Weight α-Galactosidase from the Novel Strain Aspergillus sp. D-23 and Its Hydrolysis Performance
Authors: Chen Ke , Zhang Jingyun , Liu Xing , Zhang Peiyuan , Yue Wenlong , Cai Zhiqiang
Published: January 2023

Aspergillus sp. D-23 was obtained by ultraviolet-diethyl sulfate (UV-DES) compound mutagenesis from Aspergillus sp. C18 that the α-galactosidase was purified from. According to sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and non-denaturing polyacrylamide gel electrophoresis (Native-PAGE), the purified enzyme demonstrated apparent homogeneity. The monomeric α-galactosidase’s native molecular weight was 125 kDa. The optimal temperature of α-galactosidase was 65 °C, and 75% of the initial enzyme activity could be maintained between 45 and 55 °C. Its optimal pH was 5.0 with good pH stability. After incubating for 2 h at pH 3.0–8.0, it could retain more than 80% of its original activity. Different concentrations of metal ions had different effects on the α-galactosidase activity. High concentrations of Cu2+ could strongly inhibit enzyme activity and low concentrations of Fe2+ could promote enzyme activity. Additionally, as shown by thin layer chromatography and high-performance liquid chromatography, the enzyme also had good hydrolysis ability, which could efficiently hydrolyze melibiose and raffinose by more than 95%. Therefore, these excellent characteristics could make α-galactosidase a good candidate for the food and feed industries.
Effects of Make-Up Torque on the Sealability of Sphere-Type Premium Connection for Tubing and Casing Strings
Authors: Yang Bin , Xu Honglin , Xiang Shilin , Zhang Zhi , Su Kanhua , Yang Yan
Published: January 2023

The present investigations on sealability evaluation for tubing and casing premium connections depend on the FEM with testing. This paper proposed a theoretical model to evaluate the sealability of a sphere-type premium connection based on make-up torque, which combines Hertz contact pressure and the von Mises yield criterion for calculating elastic–plastic contact pressure distribution on sealing interface and adopts the gas sealing criterion obtained from Murtagian’s experimental results for deducing gas sealing capacity. With the proposed model, the effects of additional make-up torque from the sealing interface on the sealing contact pressure distribution and key sealability parameters, including contact width, yield width, average contact pressure and gas sealing capacity, were analyzed and compared. The results show that additional make-up torque from the sealing interface closely influenced sealability parameters’ variation and gas sealing capacity. The gas sealing index based on the sealing contact energy theory should be recommended for sealability evaluation other than average contact pressure on the sealing interface. For improving gas sealability, make-up torque should be controlled accurately for ensuring enough average contact pressure and contact width but a proper yield width, and a lager sphere radius should be selected for reducing the risk of yield sticking.
Snail Shells as a Heterogeneous Catalyst for Biodiesel Fuel Production
Authors: Gaide Ieva , Makareviciene Violeta , Sendzikiene Egle , Kazancev Kiril
Published: January 2023

Homogeneous catalysis is relevant for biodiesel fuel synthesis; however, it has the disadvantage of difficult separation of the catalyst. In the present work, heterogeneous catalysis was applied for rapeseed oil transesterification with methanol, while snail shells were used as a catalyst. CaO content in the catalyst was investigated. Transesterification reactions were carried out in a laboratory reactor, ester yield was analyzed using gas chromatography. Response surface methodology was used for process optimization. It was found that the optimum transesterification conditions when the reaction temperature is 64 °C are the following: a catalyst amount of 6.06 wt%, a methanol-to-oil molar ratio of 7.51:1, and a reaction lasting 8 h. An ester yield of 98.15 wt% was obtained under these conditions.
Zeolite NaX Mass and Propeller Agitator Speed Impact on Copper Ions Sorption
Authors: Bašić Anita , Penga Željko , Penga Jure , Kuzmanić Nenad , Svilović Sandra
Published: January 2023

Sorption is often carried out in stirred batch reactors without any consideration of how much mixing is sufficient to avoid the effect of diffusion without compromising yield and cost due to overmixing. Therefore, the focus of this work was to study how the maximum sorption capacity, removal efficiency, kinetics and power consumption (P) of the studied process are affected by different mixing speeds, i.e., impeller speed/minimum impeller speed for complete suspension (N/NJS) ratio values and zeolite suspension mass concentrations. Experiments were conducted in a baffled reactor with the propeller at a standard off-bottom clearance. In addition to the experimental studies, numerical modelling approaches were carried out to investigate the sorption process using a transient multiphase computational fluid dynamics model and fitting selected kinetic models. The results show that an increase in zeolite mass leads to a slight increase in the NJS and consequently PJS. The impeller speed affects the velocities, power consumption, kinetics, final amount and removal efficiency of copper sorbed. The experimentally determined kinetic data fit Ritchie’s kinetic model well. However, for two experiments, performed at N/NJS ratios of 0.8 and 0.6, Mixed kinetic model fits better, suggesting that the second-order reaction is suppressed by diffusion. Due to the influence of diffusion, the experimentally determined sorption efficiency decreased from 59.377% to 54.486% and 46.372% for N/NJS ratios of 0.8 and 0.6, respectively.
The Relationship between Penetration, Tension, and Torsion for the Fracture of Surimi Gels: Application of Digital Image Correlation (DIC)
Authors: Park Hyeon Woo , Park Jae W. , Yoon Won Byong
Published: January 2023

A standardized method to evaluate the material properties of surimi gels has to be updated because of the lack of accuracy and the repeatability of data obtained from conventional ways. To investigate the relationships between the different texture measurement methods used in surimi gels, 250 batches of different surimi gels were used. The textural properties of surimi gels made with or without whey protein concentrate (SG-WP), potato starch (SG-PS), or dried egg white (SG-EW) were measured under torsion, tensile, and penetration tests. The correlation between the textural properties related to the deformation and hardness of surimi gels without any added ingredients (SG) was linear (R2 > 0.85). However, the R2 values of the shear strain and tensile strain of SG-WP and SG-EW were significantly lower than that of SG. The strain distributions of surimi gels with and without added ingredients were estimated by digital image correlation (DIC) analysis. The results showed that the local strain concentration in SG-WP and SG-EW was significantly higher than that of SG in the failure ring tensile test and the torsion test (p < 0.05). DIC analysis was an effective tool for evaluating the strain distribution characteristics of surimi gels upon fracture from torsion, penetration, and tension.
Parametric Effects on the Mixing Efficiency of Resonant Acoustic Mixing Technology for High-Viscosity Mixture: A Numerical Study
Authors: Khan Imdad Ullah , Guo Rui , Farooq Umar , Adhikari Suraj , Zhou Hao
Published: January 2023

Numerical investigations were conducted on the mixing efficiency of resonant acoustic mixing (RAM) technology using a high-viscosity mixture under vertically forced vibrations. The density distribution was analyzed for a mixture of high-melting explosive (HMX) and trinitrotoluene (TNT). The effects of mixing time, amplitude, frequency, fill level, and mixing vessel geometry were evaluated to determine their influence on the blend homogeneity and the efficiency of the mixing process. The results showed that amplitude and frequency both have significant influences on the mixing efficiency of the RAM process. With higher values of amplitude and frequency, the mixing efficiency was very good, and uniform mixing was achieved in a much shorter time. At the same time, it was seen that geometric changes did not affect the mixing process; in contrast, varying the fill level did have a significant effect. This approach could potentially be used for pharmaceutical blending, cosmetics, and explosive applications, where only small quantities of active particle ingredients (APIs) can change the behavior of the mixture.
Valuation of Equity-Linked Death Benefits on Two Lives with Dependence
Authors: Essiomle Kokou , Adékambi Franck
Published: January 2023

The purpose of this paper is to investigate equity-linked death benefits for joint alive and last survivor individuals. Utilizing Farlie–Gumbel–Morgenstern (FGM) type dependency modeling framework, we first analyze the joint distribution of the couple (joint alive and last survival density) when marginal distributions follow mixed exponentials and weighted exponentials distributions. Then, we derive the price of the guaranteed minimum death benefit (GMDB) product. In addition, we provide closed analytical expressions of the price of some financial contingent claim contracts (classical and exotic options). Furthermore, we present some numerical results to support our theoretical results. We show in our numerical example that it is important to model the dependency between two lives (couple) since the price changes as the copula parameter changes.
Acknowledgment to the Reviewers of Smart Cities in 2022
Authors:   Smart Cities Editorial Office
Published: January 2023

High-quality academic publishing is built on rigorous peer review [...]
Odor from Building Air Conditioners: Emission Characteristics, Odor Compounds and Influencing Factors
Authors: Pei Jingjing , Sun Luyao
Published: January 2023

The odor generated by air conditioners is an important factor influencing the perceived air quality in buildings. In this study, different types of air conditioners and air filters were investigated to study the level of odor emission related to the operation state of the compressor, to identify the odor compounds and to analyze the cooling setpoint temperature on emitted odor intensity. Results show that the odor from constant frequency air conditioner use is periodic and stronger than that from variable frequency air conditioner use due to the different operation strategies of the compressor, which affect the evaporation of condensed water on the surface of the cooling coil. Ethyl acetate, acetic acid, 2-ethyl-1-hexanol, acetaldehyde, hexanal, nonanal, toluene and n-hexane are identified as odor compounds by Odor Active Value (OAV), Gas Chromatography/Olfactory/Mass Spectrometry (GC/O/MS) and Flavornet methods. The higher cooling setpoint temperature would lead to stronger odor, due to greater release of hydrophilic odorous compounds from condensed water. In our opinion, reducing the residual condensed water in air conditioners may be the key to control odor emission before purification.
Environmental Supply Chain Risk Management for Industry 4.0: A Data Mining Framework and Research Agenda
Authors: El Baz Jamal , Cherrafi Anass , Benabdellah Abla Chaouni , Zekhnini Kamar , Beka Be Nguema Jean Noel , Derrouiche Ridha
Published: January 2023

Smart technologies have dramatically improved environmental risk perception and altered the way organizations share knowledge and communicate. As a result of the increasing amount of data, there is a need for using business intelligence and data mining (DM) approaches to supply chain risk management. This paper proposes a novel environmental supply chain risk management (ESCRM) framework for Industry 4.0, supported by data mining (DM), to identify, assess, and mitigate environmental risks. Through a systematic literature review, this paper conceptualizes Industry 4.0 ESCRM using a DM framework by providing taxonomies for environmental risks, levels, consequences, and strategies to address them. This study proposes a comprehensive guide to systematically identify, gather, monitor, and assess environmental risk data from various sources. The DM framework helps identify environmental risk indicators, develop risk data warehouses, and elaborate a specific module for assessing environmental risks, all of which can generate useful insights for academics and practitioners.
A Simple and Cost-Efficient Platform for a Novel Porcine Circovirus Type 2d (PCV2d) Vaccine Manufacturing
Authors: Noppiboon Sarawuth , Lapanusorn Neeracha , Ekkpongpaisit Pisit , Slack Sarah , Frank Stefanie , Hocharoen Lalintip
Published: January 2023

Porcine circovirus type 2d (PCV2d) is becoming the predominant PCV genotype and considerably affects the global pig industry. Nevertheless, currently, no commercial PCV2d vaccine is available. Preventing and controlling the disease caused by PCV2d is therefore based on other genotype-based vaccines. However, their production platforms are laborious, limited in expression level, and relatively expensive for veterinary applications. To address these challenges, we have developed a simple and cost-efficient platform for a novel PCV2d vaccine production process, using fed-batch E. coli fermentation followed by cell disruption and filtration, and a single purification step via cation exchange chromatography. The process was developed at bench scale and then pilot scale, where the PCV2d subunit protein yield was approximately 0.93 g/L fermentation volume in a short production time. Moreover, we have successfully implemented this production process at two different sites, in Southeast Asia and Europe. This demonstrates transferability and the high potential for successful industrial production.
Changes in COVID-19 Vaccine Acceptability among Parents with Children Aged 6–35 Months in China—Repeated Cross-Sectional Surveys in 2020 and 2021
Authors: Zhang Kechun , Liang Xue , Tam Karen , Kawuki Joseph , Chan Paul , Chen Siyu , Fang Yuan , Cao He , Zhou Xiaofeng , Chen Yaqi , Hu Tian , Chen Hongbiao , Wang Zixin
Published: January 2023

China is considering to offer COVID-19 vaccination for children aged 6–35 months. This study investigated the changes in COVID-19 vaccine acceptability and associated factors among parents with children aged 6–35 months in 2020 and 2021. Two rounds of cross-sectional online surveys were conducted among adult factory workers in Shenzhen, China. A subset of 208 (first round) and 229 (second round) parents with at least one child aged 6–35 months was included in the study. Parental acceptability of COVID-19 vaccination increased significantly from 66.8% in the first round to 79.5% in the second round (p = 0.01). Positive attitudes, perceived subjective norm, and perceived behavioral control were associated with higher parental acceptability in both rounds of surveys (p values ranged from <0.001 to 0.003). A negative association of negative attitudes with parental acceptability was observed in the second round (p = 0.02). No significant associations of exposure to information related to COVID-19 vaccination on social media with parental acceptability was found in either round of survey. Expanding the existing COVID-19 vaccination programs to cover children aged 6–35 months is necessary in China. Future programs should focus on modifying perceptions among parents to promote COVID-19 vaccination for children in this age group.
Correction: Guerrieri et al. Nasal and Salivary Mucosal Humoral Immune Response Elicited by mRNA BNT162b2 COVID-19 Vaccine Compared to SARS-CoV-2 Natural Infection. Vaccines 2021, 9, 1499
Authors: Guerrieri Mariapia , Francavilla Beatrice , Fiorelli Denise , Nuccetelli Marzia , Passali Francesco Maria , Coppeta Luca , Somma Giuseppina , Bernardini Sergio , Magrini Andrea , Di Girolamo Stefano
Published: January 2023

The authors wish to make the following corrections to this paper [...]
Human Coronavirus Cell Receptors Provide Challenging Therapeutic Targets
Authors: López-Cortés Georgina I. , Palacios-Pérez Miryam , Hernández-Aguilar Margarita M. , Veledíaz Hannya F. , José Marco V.
Published: January 2023

Coronaviruses interact with protein or carbohydrate receptors through their spike proteins to infect cells. Even if the known protein receptors for these viruses have no evolutionary relationships, they do share ontological commonalities that the virus might leverage to exacerbate the pathophysiology. ANPEP/CD13, DPP IV/CD26, and ACE2 are the three protein receptors that are known to be exploited by several human coronaviruses. These receptors are moonlighting enzymes involved in several physiological processes such as digestion, metabolism, and blood pressure regulation; moreover, the three proteins are expressed in kidney, intestine, endothelium, and other tissues/cell types. Here, we spot the commonalities between the three enzymes, the physiological functions of the enzymes are outlined, and how blocking either enzyme results in systemic deregulations and multi-organ failures via viral infection or therapeutic interventions is addressed. It can be difficult to pinpoint any coronavirus as the target when creating a medication to fight them, due to the multiple processes that receptors are linked to and their extensive expression.
A hegesztés során képződő UV-sugárzás egészségkárosító hatásának elemzése
Authors: Schramkó Márton , Abdallah Kafi , Kovács Tünde Anna
Published: January 2023

Az ívhegesztésnek számos egészségkárosító hatása van a hegesztőre. A szerzők az ultraibolya (UV) sugárzás intenzitását határozták meg a hegesztőívtől való távolság függvényében. A kutatás az ívhegesztési folyamat során keletkező UV sugárzásra fókuszált, mivel az ívhegesztés ma már széles körben alkalmazott eljárás az ipari gyakorlatban. A kísérlet során több mérést is végeztek a védőgázos ívhegesztés hatására keletkező UV sugárzás meghatározására. A védőgázos ívhegesztési eljárást az iparban automatizáltan is alkalmazzák, így a kutatás célja ipari alkalmazás esetén a biztonsági zóna kijelölése a káros sugárzás intenzitása alapján, hogy ne kelljen függönnyel lehatárolni a hegesztőrobotot munkavégzés során. A virtuális biztonsági zóna határához közeledő személyt jelzés figyelmezteti. A robotok között ez a megoldás könnyű mozgást tesz lehetővé. Amennyiben a gyártás még nem teljesen automatizált, ott a kísérleti eredmények rávilágítanak azokra a problémákra, amelyek egészségkárosodást okozhatnak, és segíthetik a biztonságosabb munkakörülmények megteremtését.
Lézerrel létrehozott periodikus felületi struktúrák (LIPSS) alkalmazásorientált felhasználása
Authors: Windisch Márk , Maloveczky Anna , Aradi László , Veres Miklós , Fürjes Péter , Vida Ádám
Published: January 2023

A lézeres kezelés által létrehozott periodikus felületi struktúrákat röviden LIPSS-eknek (laser-induced periodic surface structures) nevezzük. A lézeres felületkezelés során végbemenő fizikai folyamatok szabályozásával a kialakított felületek morfológiai és fizikai tulajdonságai beállíthatók, ennek megfelelően azok számos felhasználási lehetőséggel bírnak. A LIPSS egyik alkalmazásorientált felhasználása a felületerősített Raman-spektroszkópiában (SERS) alkalmazott SERS-hordozók, melyek segítségével molekulák extrém kis koncentrációja is kimutatható. A kísérleti munka során femtoszekundumos lézerberendezés segítségével SERS-hordozót készítettünk, melynek SERS-erősítését vizsgáltuk.
Mathematical apparatus for the analysis of economic efficiency and management of metrological support of organizational and technical systems
Authors: Krasavina A.A. , Malygin S.V.
Published: January 2023

the work is devoted to the problems of improving the efficiency and organization of metrological military units (military units). An approach to substantiating the optimal composition of the metrological support forces of the Armed Forces of the Russian Federation by linear programming is presented. The solutions for assessing the economic efficiency of the metrological support system are considered and substantiated.
On the issue of developing universal software for automating the processes of attestation studies
Authors:   Starovoytov Center of Information Technologies and Systems for Executive Power Authorities, Betin V.N. , Demjanov A.E. , Ivashchenko V.A. , Lukyanov S.E. , Suprun A.P. ,   International Centre of Informatics and Electronics
Published: January 2023

An universal approach to the creation of software systems focused on the end-to-end automation of complex high-dimensional information processes is proposed, using a single formalism as a basis, which makes it possible to describe different subject areas in a uniform way. The application of formalism for the creation of an automated system of attestation studies is considered. The practical use of the proposed software system in the process of research is considered.
«The role of the GOST RV 0015-002-2020 standard in the digital transformation of enterprises and organizations implementing the state budgetary in the context of western sanctions pressure on the Russian economy»
Authors:   Institute for INTEGRA-S Consortium: Testing and Certification of Weapons and  Military Equipment, Mozhaev O.A.
Published: January 2023

The relevance of the proposed topic is reflected in the Decree of the Government of the Russian Federation No. 1030 dated August 28, 2017 «On the Management system for the implementation of the Digital Economy of the Russian Federation program». The development of digital centers, as well as the harmonization of IT standards with standards in such areas as manufacturing enterprises, information security, the introduction of information technologies, etc.).
Principles of management in the implementing balanced and sustainable development - selected problems
Authors: Czaja Stanisław , Becla Agnieszka
Published: January 2023

The study presents selected issues concerning management principles in implementing balanced and sustainable development. These include the principles of: (1) traditional extensive economy, (2) intensive traditional economy, (3) alternative economies, (4) eco-development, (5) Sustainable Development and (6) entropy sustainable development. Selected criteria for the evaluation of these principles were also characterised.
Sustainable development in rural areas in the perspective of a decade of ecosystem restoration
Authors: Kiryluk Aleksander , Kostecka Joanna
Published: January 2023

Rural areas are included in the concept of sustainable development, and they are characterised by a great variety of flora, fauna, and habitats; apart from the function of food production, they can fulfil numerous functions related to the protection and shaping of the environment. The paper characterises the impact of agriculture on the natural environment. Selected parameters of agricultural plant production were described for the European Union, the Netherlands, and Poland. Factors significant in the context of the United Nations Decade of Ecosystem Restoration (2021-2030) were indicated. The features of agriculture in Hajnówka county (where over 50% of the area is under protection) were selected as a reference point for the expected results, treating it as a model of an organisation for the harmonious development of agriculture in the 21st century. The study highlights the importance of biodiversity in rural areas for building a sustainable human welfare strategy. The use of ecosystem services will be permanent when the elements of the Decade of Ecosystem Restoration are widely disseminated and rooted in the civic consciousness of the inhabitants of Poland and similar spaces in Europe. This decade must be advertised as widely as possible for this to happen, writing about it in various contexts.
¿Derecho al descanso laboral o al refrigerio? Comentarios al anteproyecto del Código de Trabajo
Authors: Huamán Ordóñez Luis Alberto
Published: January 2023

El autor del presente ensayo analiza el derecho al refrigerio en función del planteamiento efectuado a través del anteproyecto de Código de Trabajo planteado por el Ejecutivo y se detiene en desarrollar los alcances del derecho al descanso como género frente al refrigerio, ya que no solo debe abocarse a consumir los alimentos, con especial aunque no única referencia al almuerzo, sino también a desarrollar un espacio de interacción personal que permita al trabajador seguir su actividad de labores pasado el tiempo que el legislador le otorga para el consumo de alimentos. En este aspecto, si bien se reconoce que el derecho al descanso no tiene un referente constitucional directo, cabe dejar establecido que emana de la suma de los derechos fundamentales a la dignidad y a la salud. De acuerdo con lo sostenido, precisa la necesidad de que el derecho al descanso deba ser valorado con mayor amplitud, de manera que se enfoca en desarrollar las bases por las cuales se le debe considerar, en la misma dirección del anteproyecto del Código, como una condición de trabajo.
Flagrancia y derechos humanos. Repensando el derecho penal del ciudadano
Authors: Figueroa Gutarra Edwin
Published: January 2023

La exigencia al Estado en la lucha contra el delito, cada vez mayor, ha conducido con fuerza a considerar que existe un derecho penal del enemigo, como expresa Günther Jakobs, figura que se expresa en sanciones más duras, penas de cárcel más extensas, entre otras ideas. En ese sentido, el juzgamiento a través de Unidades de Flagrancia, como viene implementando Perú, representa una mejor coincidencia con el derecho penal del ciudadano, como propone el mismo autor, para entender un mejor afianzamiento de los derechos humanos. Persigamos el delito, es necesario, pero hagámoslo dentro del marco de respeto hacia el principio de dignidad de la persona.
La perspectiva de género desde el feminismo jurídico de Miguelina Acosta
Authors: Santos Gomero Walber Jose
Published: January 2023

La perspectiva de género es un enfoque influyente en el contexto actual; sin embargo, los estudios regionales no han profundizado en su génesis e impacto en el ámbito jurídico. Por tal razón, la presente investigación pretende evidenciar cómo dentro de las reflexiones de Miguelina Aurora Acosta Cárdenas, abogada litigante del siglo XX, ya se visualiza una clara comprensión y delimitación del fenómeno en mención; por consiguiente, a partir del análisis de los artículos «Reacción femenina en 1918» y «La absolución de Victoria Alfaro y el juez Dr. Federico Pflucker en 1919», se intenta demostrar que dentro de la obra de esta autora existen aportes significativos como el de la consideración de la perspectiva de género o análisis contextual, estructural-histórico, de la situación femenina a la hora del ejercicio del derecho a la legítima defensa.
Crowding in Private Quality: The Equilibrium Effects of Public Spending in Education
Authors: Andrabi Tahir , Bau Natalie , Das Jishnu , Karachiwalla Naureen , Khwaja Asim I.
Published: January 2023

We estimate the equilibrium effects of a public school grant program administered through school councils in Pakistani villages with multiple public and private schools and clearly defined catchment boundaries. The program was randomized at the village-level, allowing us to estimate its causal impact on the market. Four years after the start of the program, test scores were 0.2 sd higher in public schools. We find evidence of an education multiplier: test scores in private schools were also 0.2 sd higher in treated markets. Consistent with standard models of product differentiation, the education multiplier is greater for those private schools that faced a greater threat to their market power. Accounting for private sector responses increases the program’s cost effectiveness by 85 percent and affects how a policymaker would target spending. Given that markets with several public and private schools are now pervasive in low- and middle-income countries, prudent policy requires us to account for private sector responses to public policy, both in their design and in their evaluation.
Habilidades blandas en el contexto de la educación policial en Colombia: una revisión teórica
Authors: Cervantes Luis , Fajardo Ernesto
Published: January 2023

La presente investigación tuvo como objetivo analizar las habilidades blandas en el contexto de la educación policial en Colombia desde una perspectiva teórica, como aporte en la investigación institucional titulada “El perfil profesional del policía en el siglo XXI y su ruta de implementación en el proceso de formación policial”, mediante la consulta de referentes teóricos y empíricos, en respuesta a los nuevos escenarios de convivencia y seguridad en el país. Para su desarrollo se utilizó un enfoque cualitativo, a través de una investigación con alcance documental. Dentro de los resultados obtenidos se encontró que las habilidades blandas esperadas en los profesionales del siglo XXI descritas con mayor frecuencia por los autores analizados y que son de aplicación en el contexto educativo policial son: habilidades de pensamiento, comunicación efectiva, solución de problemas, flexibilidad, toma de decisiones, inteligencia emocional, habilidades de gestión, liderazgo, mediación de conflictos, creatividad y orientación del servicio. Estas habilidades han sido propuestas como insumo dentro del sistema institucional de competencias genéricas del policía, para su validación por parte de expertos en educación policial y servicio de policía y posterior fortalecimiento al interior del proceso de formación policial
Gamificación y la evaluación de los aprendizajes en educación superior
Authors: Viñolas Elizabeth , Sepulveda Liz
Published: January 2023

Al ser el juego parte del desarrollo y crecimiento del ser humano, en el proceso enseñanza aprendizaje, la gamificación juega un rol preponderante ya que facilita la resolución de problemas, desarrollar y ver nuevas formas de facilitar este proceso, tanto a docentes como a estudiantes. El presente ensayose planteó el objetivo de aplicar metodologías activas al aprendizaje de la programación añadiendo un componente que permita motivar al estudiante de Ingeniería electrónica de la Universidad Mayor de San Andrés(Bolivia)a permanecer en la asignatura mediante la gamificación y la evaluación continua de los aprendizajes. A través de la investigación-acción y el método inductivo se procedió con la aplicación de la gamificación en cada una de sus etapas donde se obtuvo resultados positivos respecto al desarrollo de la motivación en la resolución de problemas apoyados en la evaluación formativa para reducir el índice de deserción.Es posible concluir que la gamificación permite a los estudiantes reconocer que el trabajo autónomo genera mayor búsqueda de conocimiento en el desarrollo de su asignatura.
Ansiedad y miedo frente a la COVID-19 en enfermeras de los andes peruanos
Authors: Rocha Nelly , Pilco Rosa , Ramos Nury
Published: January 2023

Las enfermeras son una parte integral del sistema de salud y con la presencia del COVID-19 se enfrentan a nuevos retos muchas veces desalentadores, pues en medio de esta pandemia, trabajan arduos turnos y como resultado muchas de ellas están experimentandotrauma emocional. Objetivos:determinar el nivel de ansiedad y miedo frente a la COVID-19 en enfermeras de hospitales generales referenciales de la Región Puno –Perú, 2021. Identificar la percepción acerca de la pandemia. Método:fue diseñado como un estudio transversal y participaron 228 enfermeras, 106 del hospital referencial de la zona norte y 122 de la zona sur, seleccionadas aleatoriamente.Seevaluaron datos sobre la percepción/opinión acerca de la pandemia, las variables de ansiedad a través de laEscala de Ansiedad Generalizada (GAD-7), y miedo con la Escala de evaluación de síntomas de miedo al COVID-19. Los instrumentos se aplicaron de manera presencial. Para el procesamiento estadístico se empleó el IBM Statistical Package for Social Sciences versión 25, probando la hipótesis con el estadígrafo R de Pearson. Resultados:el nivel de ansiedad y miedo es moderado representado por 73.2% y 64.5%, respectivamente. 85.1% tienen miedo de llevar la COVID-19 a su casa; 83.8% piensa que puede contagiarse con el virus SARS-Cov 2 al realizar su trabajo; y 83.3% opinan que su familia tiene miedo de que ellas, como profesionales de primera línea de atención, sean portadoras asintomáticas de la enfermedad.Conclusión:existe relación moderada positiva entre el miedo y la ansiedad porque se encontró P=0,001< P=0,005, es decir, a mayor ansiedad, el miedo se incrementa.
Consumo de alcohol y resiliencia en adolescentes de una institución educativa secundaria peruana
Authors: Lipa-Tudela Frida
Published: January 2023

El objetivo de la investigación fue determinar la relación entre el consumo de alcohol y resiliencia en adolescentes de una institución educativa en Perú. La metodología fue de enfoque cuantitativo, diseño no experimental, de corte transversal, correlacional. Los resultados fueron que el 40 % tienen la edad de 12 a 14 años, el 50 % son sexo femenino, el 16% son de quinto grado, el 39% si consumen alcohol por primera vez, el 63% tienen la edad de inicio de consumo de alcohol12 a 14 años, el 55% tienen introspección medio, el 62% independencia bajo, el 51% interacción medio, el 45% iniciativa medio, el 40% humor medio, el 37% creatividad medio, el 63% moralidad alto, el 64% tienen consumo de alcohol de bajo riesgo y la resiliencia es medio. Finalmente, a través de la prueba estadística Chi cuadrada se comprobó que no existe relación entre el consumo de alcohol y la resiliencia en adolescentes, sin embargo, según la prueba de Elorza existe relación entre el sexo, el grado, el inicio de consumo de alcohol por primera vez y la resiliencia, asimismo, el consumo de alcohol y la resiliencia (independencia, humor y creatividad).
Principios de la sociedad inca: Ama Quella, Ama Sua, Ama Llulla y el desarrollo de la buena convivencia en estudiantes andinos
Authors: Vargas Diana , Velásquez-Yupanqui Idemeyr , Cutipa Reynaldo
Published: January 2023

a investigación tuvo como objetivo determinar la relación que existe entre los principios de la sociedad inca y el desarrollo de la buena convivencia escolar en los estudiantes de unaInstitución Educativa Secundariaen Puno, Perú. Metodológicamente, se realizó bajo el enfoque cuantitativo, es de tipo descriptivo correlacional, el muestreo fue no probabilístico de tipo intencional,conformadapor 142 estudiantes, a quiénes se les aplicó un cuestionario que consta de 15 ítems referente a los principios de la sociedad inca y 15 respecto a desarrollo de la buena convivencia en estudiantes andinos. Para establecer la correlación entre las variables estudiadas, se utilizó el coeficiente Rho de Spearman. Los resultados de la investigación indican que existe una correlación positiva alta entre los principios de la sociedad inca y el desarrollo de la buena convivencia escolar existe una correlación positiva alta, el mismo que se representa con la prueba de Correlación Rho de Spearman con un valor de 0,769. Por tanto, se concluye que a mayor valoración de los principios de la sociedad inca: Ama Quella, Ama Sua, Ama Llulla, será se desarrollará una buena convivencia escolar en estudiantes andinos.
Estrategias habituales de enseñanza en colegios rurales aymaras
Authors: Sosa-Gutierrez Fredy , Vilca-Apaza Henry
Published: January 2023

El trabajobuscó describiry analizarlas estrategias de enseñanza aprendizaje utilizadas por los profesores del colegio rural Artesanal Yaputira -Huancané en Perú, esto devela las estrategias de enseñanza más usados por los profesores en colegios secundarios aymaras. El trabajo corresponde al enfoque cuantitativo, siendo su diseño transeccional descriptivo. En su desarrollo se aplicó una encuesta dirigida a todos los estudiantes, en el que dieron cuenta, respecto a las estrategias de enseñanza recurrentes por el docente. La estadística utilizada fue el paquete estadístico SPSS Statistics 25, en el que se determinó que los docentes en un 59.4% se ubica en la escala de casi siempre usan estrategias para indagar el conocimiento, un 43.75% se ubican en la escala algunas veces hacen uso de las estrategias que promueven la organización de la información y un 46.9% se ubica en la escala algunas veces usan estrategias grupales. Esto significa que, los estudiantes señalan que sus profesores pocas veces utilizan estos tipos de estrategias en el proceso de enseñanza aprendizaje. Al mismo tiempo, evidencia una necesaria mejora en formación inicial docente, de otro lado, una asistencia débil en los procesos de monitoreo y acompañamiento de los órganos intermedios de gestión descentralizada del Ministerio de Educación.
INTEGRATIVE MODEL OF HOLISTIC KNOWLEDGE OF SCHOOLCHILD’s INDIVIDUALITY BY TEACHER. MESSAGE 1. THEORETICAL SUBSTANTIATION AND OBJECTIVES OF THE RESEARCH
Authors: Karakulova O.Yu.
Published: January 2023

From the standpoint of a systematic approach, the process of teacher’s cognition of the integral individuality of a student is considered. The purpose of the study: through the integration of various theories and approaches, to substantiate a new system-integrative approach to pedagogical cognition of the integral individuality of students by a teacher. Research objective: to show that the systems "subject", "integral individuality", "cognition" form a trinity that ensures the functioning of the resulting polysystems: "integral individuality - cognition - object", "integral individuality - cognition - subject", "integral individuality - cognition - integral individuality". Thus, the most complete knowledge of student’s integral individuality by a teacher is ensured. Pedagogical knowledge is defined as a multi-level process of studying the student's individuality as an object and as a subject of cognition, based on scientific and theoretical knowledge of the properties of the student's integral individuality in dialectical unity with practical knowledge about the student and the teacher's reflexive knowledge about himself, formed in the process of interpersonal interaction in the dyad "teacher - student". The resultative and procedural directions of the study of teacher’s cognition of the student are singled out, namely: the study of the relationship between the properties of the integral individuality of the student and their “life manifestations” observed by the teacher, the role of reflexivity and objective factors of pedagogical activity in the process of cognition. The novelty and theoretical significance of the work is determined by the fact that it fits into the current direction of psychological research - the development of psychodiagnostic tools for systemic psychological research that is in demand in pedagogical and social practice. The practical result of the study is the creation of a model of holistic cognition of the integral individuality of a student by a teacher, including the development of a program for scientific and practical observation of a teacher over the "life manifestations" of the properties of the integral individuality, as well as a questionnaire for the integral individuality of schoolchildren of different ages.
ANALYSIS OF THE GTO COMPLEX ORGANIZATION AND ITS IMPLEMENTATION IN THE SYSTEM OF GENERAL EDUCATION OF THE UDMURT REPUBLIC
Authors: Novokreshchenov V.V. , Sokolova N.G.
Published: January 2023

The article presents the results of a sociological study, which allowed the authors to analyze the state and the results of the implementation of the All-Russian physical culture and sports complex "Ready for Labor and Defense" (abbreviated as GTO). With the help of the Google Forms platform, a sample survey of physical education teachers representing 230 urban and rural schools of the Udmurt Republic was conducted. The results of it with a sufficient degree of reliability allow us to judge the state of this process in the system of general education in Udmurtia. The purpose of the study was to obtain data on the behavior of the controlled system (implementation of the GTO complex in the system of general education) and further adjustment of management decisions. In particular, new data were obtained regarding the factors impeding the implementation of the GTO complex, as well as motivating and stimulating mechanisms of schoolchildren to participate in the tests in order to assess their activity in meeting the standards. In addition, the data were collected regarding the actual state of work organization on the implementation of the GTO complex in terms of the presence of management bodies that increase its effectiveness (councils and organizing committees for the GTO) and planning documents (plans, programs, work schedules for the implementation of the GTO among students). The population of schools was segmented according to the “availability and completeness of the organization and planning of the implementation of the GTO complex”, which made it possible to fix and evaluate the following factors - those constraining the implementation of the GTO complex in the school education system as well as mechanisms of motivation and stimulation of students that can improve the work necessary to implement the complex; the level of activity of students of junior, middle and senior classes to fulfill the standards of the GTO complex.
ITINERÁRIOS DO PENSAMENTO GEOGRÁFICO, PRECURSORES E DESAFIOS
Authors: Chicombo Tomé Francisco , Araújo Aureliane Aparecida de
Published: January 2023

O presente trabalho busca apresentar alguns apontamentos acerca da evolução do pensamento geográfico. A geografia recente, apresenta áreas potentes, embora o tronco do conhecimento encontra-se fragilizado em função da fragmentação dos paradigmas. Ao recorrer à base epistemológica, revisitamos conhecimentos elencados desde os primeiros unificadores da Geografia. Para isso, realizamos uma pesquisa bibliográfica, visando fundamentar teoricamente o estudo, em sua articulação com o conhecimento geográfico que precede a idade contemporânea. Desta feita, percorremos itinerários fundamentados nas bases evolutivas do pensamento geográfico, ao contemplar também trajetórias envolvendo gregos descritores de narrativas epopeicas, a exemplo da Odisseia de Homero. Transitando entre mitos e realidades, o período envolveu marinheiros, navegantes aos quais identificamos etapas significativas e necessárias para os vindouros saberes sistematizados. Neste sentido, torna-se premente lançar um olhar filosófico sobre a ciência geográfica e, assim, possibilitar indagações sobre os desafios da abordagem integrada.
APPLICATION OF GILLESPIE ALGORITHM FOR SIMULATING EVOLUTION OF FITNESS OF MICROBIAL POPULATION
Authors: GIL Jarosław , POLAŃSKI Andrzej
Published: January 2023

In this study we present simulation system based on Gillespie algorithm for generating evolutionary events in the evolution scenario of microbial population. We present Gillespie simulation system adjusted to reproducing experimental data obtained in barcoding studies – experimental techniques in microbiology allowing tracing microbial populations with very high resolution. Gillespie simulation engine is constructed by defining its state vector and rules for its modifications. In order to efficiently simulate barcoded experiment by using Gillespie algorithm we provide modification - binning cells by lineages. Different bins define components of state in the Gillespie algorithm. The elaborated simulation model captures events in microbial population growth including death, division and mutations of cells. The obtained simulation results reflect population behavior, mutation wave and mutation distribution along generations. The elaborated methodology is confronted against literature data of experimental evolution of yeast tracking clones sub-generations. Simulation model was fitted to measurements in experimental data leading to good agreement.