bluuebunny/crossref_metadata_2025 huggingface dataset:
Toothpaste Activity Test of Laban Leaf Methanol Extract (Vitex pinnata) Against the Growth of Streptococcus mutans Bacteria
Authors: Nuraskin Cut , Reca Reca , Salfiyadi Teuku , Abdurrahman Abdurrahman , Faisal Teuku Iskandar , Soraya Cut
Published: June 2021

BACKGROUND: One of the natural ingredients that can be used as a substitute for preventing dental caries is the methanol extract of Laban leaves. Laban contains various compounds that are known to have antibacterial properties. The traditional ability of Laban Leaf Methanol Extract has been proven to treat diseases caused by pathogenic microorganisms.
AIM: The aim of the study was to analyzing the activity test of Laban leaf methanol extract toothpaste (Vitex pinnata) against the growth of Streptococcus mutans bacteria.
METHODS: This type of laboratory experimental research (true experimental design) with post-test only control group design. This research was conducted at the Poltekkes Pharmacy Laboratory of the Ministry of Health in Aceh in July-August. The research sample consisted of Laban leaves collected randomly in the Ie Seu Um Geothermal area of Selawah Agam Aceh Besar. Data analysis was carried out descriptively. Antibacterial activity data were statistically processed with one-way ANOVA at a confidence level of α 0.05.
RESULTS: The organoleptic test results observed for 3 weeks showed that there were differences in color and aroma; the higher the concentration of the resulting color, the darker it was, and resulting in a soft, sweet taste in the toothpaste of laban leaf methanol extract. The pH acidity test results showed an effect of storage time (the week I, week II, and week III) on toothpaste’s pH value. The viscosity test results showed that the toothpaste formula combined with the methanol extract of Laban leaves met the SNI 12-524-1995 standards regarding toothpaste. Toothpaste formula F3. 4.5% has the greatest viscosity, ranging from 241.0 (PDAs), and followed by F2. 240.4%, and F1. 237.6%. The higher the active ingredient concentration, the greater the viscosity value. The foam formation test results show that the foam’s stability is greatly influenced by particle size. The more the particle size, the lower the foam stability. ANOVA test results based on the concentration of significance value (0.000) <0.05, there is a difference in the number of bacterial colonies based on the concentration variable. ANOVA test results based on the repetition of significant values (0.423)> 0.05, which means that all repetitions have the same effect on the number of colonies, so there is no difference in the number of colonies based on the repetition variable.
CONCLUSION: Minimum inhibitory concentration of toothpaste laban leaf methanol extract against S. mutans growth was aimed at a concentration of 4.5%, with an average number of bacterial colonies 108.5 × 10−7 CFU/mL).
MGMT Immunohistochemical Expression in Colorectal Carcinoma and its Correlation with Tumor Progression
Authors: Ahmed Mohamed , Bayoumi Badawia , Abdallah Samira , Elserafy Maya
Published: June 2021

Introduction: There is an urgent need to identify predictive features and markers for colorectal carcinoma (CRC) progression and treatment. This study aimed to assess O6-methylguanine DNA methyltransferase (MGMT) expression in CRC and correlate with the clinico-pathological aspects of the tumor, also to evaluate the relationship between different histopathologic parameters and tumor progression.
Material and Methods: The study was carried on 70 colectomy using formalin fixed paraffin embedded tumor tissue. Immunohistochemistry was used to detect MGMT expression, and clinico-pathologic aspects as well as Tumor budding, type of desmoplastic reaction, inflammatory lymphocytic milieu, pattern of invasive front and necrosis were assessed Then correlated with MGMT expression and tumor progression, using parametric and nonparametric statistical methods.
Results: MGMT Loss of expression was detected in 42.9% of CRC cases. MGMT expression status was significantly correlated with tumor stage and metastatic status (p<0.05), while it was not correlated with other clinic-pathologic features, (p>0.05).  Desmoplastic reaction (DR), tumor budding, stromal tumor infiltrating lymphocytes (TIL-S) and necrosis were correlated with tumor stage (p<0.05). DR correlated with tumor budding (p<0.05). Both types of TIL and Crohn’s-like lymphoid reaction (CLR) showed a mutual correlation (p<0.05).
Conclusion: MGMT high expression and histopathologic parameters as DR, tumor budding, inflammatory lymphocytic milieu and necrosis could be correlated with CRC progression.
A Drowned Diver – Four Expert Witness Opinions – Who is Right?
Authors: Lalić Hrvoje
Published: June 2021

BACKGROUND: The paper describes the case of a drowned diver in the Adriatic Sea near Pula, Croatia.

CASE PRESENTATION: The deceased diver had not been trained at any Health and Safety at Work programs nor had he been examined by the occupational medicine (OM) specialist. The pathologist in Pula concluded that this accident was caused by drowning and that diver’s blood was saturated with 38% carboxyhemoglobin (COHb). The second pathologist in Zagreb concluded that the diver drowned due to atherosclerosis sickness but that COHb was not present in his blood. The third expert witness from Forensics in Rijeka evaluated that the diver died due to increased exertion while diving, due to atherosclerosis and weakened heart. The fourth, the OM specialist expert witness from Rijeka, explained that the diver was a healthy athlete who died due to faulty diving equipment.

CONCLUSION: Persons who work under the special working conditions should be examined at an Occupational medicine department as well as trained for work in a safe way. Periodical examinations and permanent training courses should be provided. That way the risk of fatal accidents would be reduced to a minimum.
Antimicrobial Activity and Polyphenol Profiles of Hydroalcoholic Extracts of Thymus rasitatus Klokov and Thymus eremita Klokov
Authors: Ivasenko Svetlana , Zhumabekova Ainur , Ludwiczuk Agnieszka , Skalicka–Wozniak Krystyna , Marchenko Alexandr , Ishmuratova Margarita , Poleszak Eva , Korona-Glowniak Izabela , Akhmetova Saule , Karilkhan Islambek , Loseva Irina
Published: June 2021

BACKGROUND: A possible reduction in stocks of medicinal plant raw materials of Thymus serpyllum L. and Thymus vulgaris L. leads to the need to expand the raw material base of the official medicinal plants with using of endemic species of the flora of Kazakhstan, in particular, Thymus rasitatus Klokov, and Thymus eremita Klokov.

AIM: The aim of the study was to study the possibility of using 70% ethanol extracts of T. rasitatus and T. eremita as antimicrobial agents.

MATERIALS AND METHODS: The aerial parts of T. rasitatus and T. eremita were extracted with 70% ethanol using ultrasound assisted extraction. The qualitative and quantitative analyses of the 70% ethanol extracts were determined using the liquid chromatography-detection-ESI-mass spectrometry-(MS)/MS technique. The study of the antimicrobial activity of these extracts was performed for eight strains of Gram-positive bacteria, six strains of Gram-negative bacteria, and four cultures of fungi.

RESULTS: Chromatographic analysis of hydroalcoholic extracts of both investigated Thymus species showed very similar phenolic compounds composition. In both cases, the major components are luteolin-7-O-glucoside and rosmarinic acid. About 70% ethanol extracts of T. rasitatus and T. eremita have a broad spectrum of antimicrobial activity, exhibit the bactericidal or bacteriostatic activity against all tested bacteria and fungi at concentration range of 0.0195–20 mg/ml, but differ in their potency against tested strains of microorganisms.

CONCLUSION: About 70% ethanol extracts of T. rasitatus and T. eremita, endemic plants in the flora of Kazakhstan, can be considered as potential drugs with a wide spectrum of antimicrobial activity. The results of chromatographic analysis could be used for drug standardization.
A Case of Acute Stress in Post-hypnotized Patient
Authors: Pratiwi Cut Rika , Effendy Elmeida , Husada Muhammad Surya
Published: June 2021

Background: Mental health conditions that can occur immediately after a traumatic event is called acute stress reaction; in this case, happens after hypnosis. This can cause a variety of psychological symptoms without attention or treatment, causesost-traumatic stress disorder.
The psychological symptoms can negatively affect the quality of life, especially the reactions arise after a traumatic event that after being hypnotized. Hypnosis works by changing the activity in brain regions associated with attention or alertness. At the time hypnotised, we saw a very high level of concentration, so that suggestions given to him will be more easily accepted.
Case Report: The case presented is the hypnotic impact of acute stress reactions. A woman named Mrs. J 63 years old. The Karo tribe who experienced anxiety, fear, and difficulty sleeping after experiencing hypnosis four days ago. This experienced it after being hypnotized at home.
Conclusion: Hypnosis plays a role in all parts of life involving human mind. Hypnosis is a science that exploits the potential mental and hidden in humans, known as the subconscious. in medical health, hypnosis therapy is very important, what we need to realize is that hypnosis with bad intentions can harm humans. Hypnosis incident was reported in patients who suffer from post traumatic stress disorder. found in many women. older women are more vulnerable to acute stress. Previous research has shown that hypnotic susceptibility correlated with personality traits.
Comparison between SRK/T and Haigis Formulas on Visual Acuity of Patient with Senile Cataract Post-Phacoemulsification
Authors: Delfi Delfi , Virgayanti Vanda , Gunawan Hendra
Published: June 2021

BACKGROUND: Cataract contributes to the most common cause of blindness worldwide. Cataract surgery is the most performed surgery in the world. To achieve optimal results, pre-operative biometric must be accurate and the use of a formula for measuring the strength of the intraocular lens (IOL) accurately must be used. SRK-T and Haigis are formulas applied in the calculation of IOLs.

AIM: The objective of the study was to determine the evaluation of visual acuity after phacoemulsification using the SRK/T and Haigis formulas.

METHODS: This was an observational prospective analytic study at Medan Baru Eye Hospital from June 2019 to August 2019. Following the examination, patients were required further follow-up on 7–30 days post-phacoemulsification.

RESULTS: The number of subjects was 122 patients (122 eyes), 84 patients were observed, and 38 patients did not come back for control. This study was within the value of p = 0.053. Prediction of refractive errors after phacoemulsification for myopia identified using SRK/T formula was more common, resulting in 3 eyes (75.0%) compared to the Haigis formula. On contrary, the prediction for emetropia was mostly discovered on Haigis formula which amounted to 41 eyes (51.25%) compared to the SRK/T formula.

CONCLUSIONS: There was no significant difference in predicting post-phacoemulsification visual acuity between SRK/T and Haigis formula.
Submucosal Uterine Fibroid in Grand Multipara Woman: A Case Report
Authors: Rusda Muhammad , Lubis Arvitamuriany Triyanthi , Hisworo Muhammad Ramadhan , Rambe Andrina Yunita Murni
Published: June 2021

Background: to report and analyze a case that diagnosed with submocous uterine fibroid in grand multiparity woman.
Methods: Case Report
Case: a 49 years woman, P7A0 came with chief complaints vaginal bleeding that has been experienced since one year ago getting worse in 2 months. Her general condition was within normal limit and there was no abnormality in physical examination, by vaginal examination there was blood in the vagina, origin from the External Uterine Orificium (EUO),bimanual examination showed anteflexion uterus with normal size, right and left adnexa within normal limits. From transvaginal ultrasound we found submucous uterine fibroid size 3 x 3 cm, we decided to perform Total Abdominal Hysterectomy.
Conclusion: Hysterectomy is a progressive and definitive uterine fibroid procedure. For women who do not want to conceive and/or women over 40-50 years of age, in particular.
Alteration of the feeding behavior of an omnivorous fish, Scardinius acarnanicus (Actinopterygii: Cypriniformes: Cyprinidae), in the presence of fishing lights
Authors: Tsounis Lambros , Kehayias George
Published: June 2021

Fishing with light is an old and common practice yielding a substantial catch volume globally. Despite the popularity of the method and the efforts to improve it, there is a lack of field studies on the effects of light on the feeding preferences of the attracted fishes. A previous report suggested that purse seine fishing lights can differentiate the feeding preferences of the approaching fishes, such as Atherina boyeri Risso, 1810 in Lake Trichonis (Greece). The presently reported study aims to verify these findings by investigating the diet of the endemic Scardinius acarnanicus Economidis, 1991. The feeding behavior of S. acarnanicus was studied from 2016 to 2019 through gut content analysis, in specimens from Lake Trichonis that came from purse seining with light and specimens caught without light. The same investigation was carried out comparatively in specimens taken by gillnets from two nearby lakes (lakes Ozeros and Amvrakia), where S. acarnanicus is present, but no fishing with light is exercised. The stomach content analysis conducted on 699 S. acarnanicus specimens revealed the intense effect of light on its diet resulting in the alteration of its feeding habits towards fish predation and especially Atherina boyeri. On the contrary, the specimens taken with the use of gillnets, from the three lakes, showed a typical omnivorous feeding behavior. The findings of the presently reported study support the assumption that the elevated concentration of fish close to fishing lights alters the feeding behavior of certain species making them predators. Considering that fishing with light is practiced worldwide, this could be of great ecological significance to the ichthyofauna not only of inland waters but also of marine areas, affecting perhaps several commercial species.
Réponse
Authors: Roelens Camille
Published: June 2021

Ce texte est une lecture, assumant une part de subjectivité et un ancrage fondamental en philosophie politique de l’éducation, du propos développé dans ce même dossier par Gaspard Turin (prolongement d’un dialogue initialement entamé lors d’une participation commune à l’évènement scientifique support de ce numéro). Une première partie de notre propre texte s’attache à montrer que la mise en question de la responsabilité éducative dans ses conditions de possibilités actuelles constitue le fil rouge de la démarche que Turin propose. Une seconde partie, plus courte, entreprend d’insérer deux marque-pages thématiques dans le texte de Turin, et invite ainsi le lecteur à y considérer son apport pour une posture éducative autoréflexive et autocritique d’une part, pour une réinvention de la notion de culture générale d’autre part.
Réponse
Authors: Boldrini Miranda
Published: June 2021

Dans cette réponse à l’article de Layla Raïd, nous proposons de problématiser le rapport entre émotions morales et les notions d’« attention » et d’« amour » chez Iris Murdoch. Dans ce cadre, nous suggérons une interprétation de cette relation qui se concentre sur la dimension épistémique de la notion d’« attention » de Murdoch.
Le lexique de l’échelle des êtres dans le Traité des animaux d’Aristote et le De animalibus d’Albert le Grand
Authors: Clesse Grégory
Published: June 2021

Cet article étudie le concept de l’échelle des êtres à partir des enjeux lexicaux impliqués par les différentes étapes de transmission du Traité des animaux d’Aristote dans l’Occident médiéval latin. Une attention spécifique est accordée à la comparaison des termes employés dans le texte grec d’Aristote et dans les traductions arabes, arabo-latine (par Michael Scot) et gréco-latine (par Guillaume de Moerbeke). Par ailleurs, l’article examine la place occupée par le commentateur dominicain Albert le Grand dans ce processus de transmission. En particulier, il s’agit d’analyser comment celui-ci aborde la question de la progression continue propre à la notion de scala naturae et déploie de multiples échelons intermédiaires qui sous-tendent le schéma naturel qu’il expose.
Les traités d’Ichtyologie vers 1555 - La naissance de la « peinture scientifique »
Authors: Kolb Katharina
Published: June 2021

L’image scientifique prend naissance au xvi e  siècle, libérée de tous les aspects symboliques, décoratifs ou encore moralisants. Les textes d’Aristote ou de Pline l’ancien fournissent aux hommes de science de la révolution scientifique, en particulier aux ichtyologues comme Pierre Belon et Guillaume Rondelet, les sources et ainsi les bases de leurs propres études. L’évolution iconologique de ce que les ichtyologues appellent le « portrait » d’un animal influencent considérablement l’iconographie scientifique. Les aspects de complémentarité entre texte et image et d’autonomie de l’image sont une caractéristique de la représentation scientifique de la Renaissance. Les naturalistes ont la volonté de transmettre un savoir et non plus des croyances.
Au-delà de la psychiatrisation ? Le cas des adolescents « difficiles » en France
Authors: Gansel Yannis
Published: June 2021

Alors que les professionnels de l’enfance rejettent massivement l’introduction du trouble des conduites en France au cours des années 2000, la catégorie d’adolescents « difficiles » rencontre un succès et organise des actions institutionnelles. Elle repose sur des savoirs psychanalytiques sur les déviances et sur une critique de leur pathologisation. À partir d’une enquête ethnographique, cet article réexamine la notion de psychiatrisation. Plutôt que l’établissement d’une juridiction professionnelle, la psychiatrisation est ici une façon clinique de poser un problème commun. Elle permet de constituer des collectifs professionnels mais empêche une lecture sociale du problème.
Problématiser les effets du technocapitalisme par la fiction ? Des marges aux mondes sociaux du cyberpunk
Authors: Rumpala Yannick
Published: June 2021

Cette contribution vise à montrer l’intérêt heuristique qu’il peut y avoir à appréhender les marges, milieux interlopes, déchéances et errances, pratiques troubles et plus généralement les mondes sociaux du cyberpunk comme des terrains d’enquête aidant, grâce à leur forme fictionnelle exploratoire, à problématiser et penser des tendances sociologiques de fond et notamment l’évolution des conditions d’existence dans les sociétés d’un technocapitalisme en expansion. Derrière l’exubérance technologique, les récits et les mises en scène de ce sous-genre de la science-fiction déploient en effet un ensemble relativement cohérent de visions et de représentations, qui peuvent aussi offrir des ressources pour réfléchir aux effets de l’insécurité sociale sur les subjectivités, aux formes d’expression des marginalités, aux prises que des existences rendues fragiles et incertaines peuvent retrouver dans des sociétés disloquées, et aux logiques par lesquelles s’adaptent les activités criminelles dans ce nouveau contexte.
La dégénérescence dans les coopératives autogérées et des moyens de la combattre
Authors: Hévin Samuel
Published: June 2021

On ne compte plus aujourd’hui les espoirs déçus d’initiatives alternatives, porteuses, à leurs débuts, de valeurs fortes ayant peu à peu cédé la place au pragmatisme économique. Principes démocratiques et organisation alternative du travail se heurtent souvent à des contraintes économiques, mais subissent aussi l’effet de contraintes organisationnelles internes. C’est ce qui ressort des approches classiques de la dégénérescence des organisations. Celles-ci affirment que la nécessaire adaptation à l’environnement tend à faire émerger, au sein de structures pourtant pensées comme alternatives, une bureaucratie qui finit par prendre le pas sur les valeurs politiques initialement incarnées par l’organisation. Cet article propose une étude de ce processus de dégénérescence et des moyens d’y résister à travers l’exemple de la coopérative AlterConso.
Vers un système d’information prenant en compte les questions sociales et environnementales
Authors: Nefti Michel
Published: June 2021

La méthode ADESS LOGIC ® (Aide à la Décision Environnementale, Sociale et Sociétale) s’inscrit dans la lignée d’un mouvement d’intégration de problématiques sociales et environnementales dans le système d’information comptable qui existe depuis les années soixante-dix. Elle propose une prise en compte des impacts des organisations selon plusieurs dimensions. Après avoir rappelé les arguments en faveur d’une transformation de la comptabilité financière, nous interrogeons le rôle que les experts comptables peuvent jouer dans cette évolution. Pour mieux comprendre les enjeux conceptuels lié aux comptabilités élargies, une étude de cas permet de comparer différentes propositions françaises et de décrire un contexte fait de différents acteurs.
La violence envers les animaux dans l’espace belge aux Temps modernes
Authors: Riguelle William
Published: June 2021

En prenant pour cadre les Pays-Bas méridionaux et la principauté de Liège aux xvii e et xviii e  siècles, cette étude propose d’aborder la question de la brutalité humaine envers les animaux. Il s’agit de mesurer l’ampleur d’une violence bien présente, d’en comprendre les causes et de percevoir les éventuelles évolutions à ce sujet au cours des deux siècles étudiés. Bien que sur le plan théorique, les contestations des mauvais traitements qui sont infligés aux bêtes existent et ne sont pas neuves, aucun changement majeur n’est perceptible dans la pratique à travers la documentation du passé, composée de normes, de journaux, de rapports de police ou encore de chroniques. Ce constat permet de nuancer le processus de civilisation observé par Norbert Élias, modérant les progrès en matière de sensibilité et de canalisation de la violence à la fin du xviii e  siècle, rejoignant ainsi une remise en cause de ce processus déjà pointée par plusieurs chercheurs. Cette étude éclaire également sur la place de l’être humain dans les sociétés occidentales de l’Ancien Régime, et met en avant une série de ses activités et pratiques.
Machine Intelligence of Pi From Geometrical Figures With Variable Parameters Using SCILab
Authors: Mandal Ankita , Dutta Soumi , Pramanik Sabyasachi
Published: June 2021

In the present research work, the use of geometrical figures have been made for the calculation of the value of pi. Instead of circle and square, ellipse and rectangle had been used to derive the value of pi. Ellipse can be considered as an extension of a circle where it had been stretched in two dimensions in unequal manner giving rise to the concept of major axis and minor axis. These axes are considered as the length and breadth of the considered rectangle. The ellipse has been considered within the rectangle and some random points are generated to see the position occurrence of the generated points. If the point lies within the ellipse, then the specific counter is incremented; otherwise, the counter for the rectangle is incremented.
Quantitative and Visual Exploratory Data Analysis for Machine Intelligence
Authors: Patel Dharmendra Trikamlal
Published: June 2021

Exploratory data analysis is a technique to analyze data sets in order to summarize the main characteristics of them using quantitative and visual aspects. The chapter starts with the introduction of exploratory data analysis. It discusses the conventional view of it and describes the main limitations of it. It explores the features of quantitative and visual exploratory data analysis in detail. It deals with the statistical techniques relevant to EDA. It also emphasizes the main visual techniques to represent the data in an efficient way. R has extraordinary capabilities to deal with quantitative and visual aspects to summarize the main characteristics of the data set. The chapter provides the practical exposure of various plotting systems using R. Finally, the chapter deals with current research and future trends of the EDA.
Energy Center Selection in G7 Industry With Fuzzy MOORA
Authors: Yüksel Serhat , Mikhaylov Alexey , Khomyakova Lyubov
Published: June 2021

In this study, energy center selection of G7 countries is examined. In this context, firstly, the studies in the literature have been evaluated in detail, and seven different criteria have been determined which may affect this selection. Taking these seven different criteria into consideration, G7 countries are ranked by fuzzy MOORA method according to energy center selection performance. According to the results, Japan and Germany are the most successful countries. On the other hand, it was concluded that France and Italy ranked last in terms of energy center selection performance. Hence, especially the countries in the last rankings should be more careful in selecting energy center. In this framework, the customer potential, the training profiles of the customers, the potential of the company with investment demand, the previous payment performance of these companies, and the market risks should be considered by the energy companies while opening new branches.
The Economic and Environmental Importance of Akkuyu Nuclear Power Plant in Turkey
Authors: Uluer Gülsüm Sena , Çağlayan Çağatay
Published: June 2021

Turkey's energy consumption grown because Turkish economic volume, industrialization, and population have increased. The way to meet this energy need is to have a sustainable energy resource. Turkey does not have the enough reserves of fossil fuels such as oil and natural gas. Therefore, it is an energy importer country. So, the current account deficit is one of the main problems of the Turkish economy. When it is considered that increase in the importation of fossil fuel costs and these fuels' damages to the environment, Turkey has the need for environmentally friendly and sustainable energy sources. In this context, Turkey plans to meet energy needs with nuclear power plants (NPP). The first NPP will come into operation at Akkuyu location in Mersin with a total installed power of approximately 10,000 MW. Turkey aims to reduce the current account deficit by reducing energy imports. In addition, environmental protection will be ensured as much as provided economic growth. In this study, the importance of Akkuyu NPP for Turkey and relevant literature are investigated.
Co(OH)2/TiO2 Nanotube Composite for High-Rate Performance Supercapacitor
Authors: Ren Xin , Qi Peng Tao , Du Liang , Cheng Li Li , Gao Zhi Liang , Wang Ming
Published: June 2021

The TiO2 nanotube arrays were prepared on Ti plate by anodizing technology, and then Co (OH)2 nanoparticles in-situ grew into TiO2 nanotubes with "Tube-particle bonding" nanocomposited structure. Co (OH)2 nanoparticles with a particle size of 40.5±8 nm were infiltrated in the TiO2 nanotube arrays, and the Co (OH)2 outside the tube presented a nanosheet structure. The specific capacitance of the Co (OH)2/TiO2 nanotube array composite reached 260 F/g at the current density~1 A/g. The capacity retention rate was 82.5 % after 2,000 cycles at the current density~5 A/g. The high-rate performance of the Co (OH)2/TiO2 nanotube array composite reached 210 F/g at the current density~10 A/g.
A Study on the Impact of Genetic Polymorphisms of Cytokines TNFα, IFNγ and IL10 in South Indian Leprosy Patients
Authors: Kolla Venkata Karunakar , Sultana Shehnaz , Davala Samuel Abraham Joshi , Valluri Vijaya Lakshmi
Published: June 2021

Background:

Leprosy (Hansen's disease) is a chronic, debilitating disease predominantly of the peripheral nervous system characterized by the impairment of peripheral nerves and subsequent sensory loss caused by Mycobacterium leprae. The pro- and antiinflammatory cytokine genes play a major role in nerve damage in leprosy.

Aims and Objectives:

The objective of the present study is to ascertain the association of cytokine gene polymorphisms TNFα - 308G/A (rs 1800629), IFNγ +874A/T (rs 2430561), and IL10 - 1082G/A rs 1800896 in causation with leprosy.

Materials and Methods:

The present study comprised 365 leprosy patients and 185 control subjects. The polymorphisms in TNFα-308, IFNγ+874, and IL10-1082 genes were typed using the amplification refractory mutation system polymerase chain reaction method (ARMS PCR).

Results:

The present study found significant association between IL10-1082 GA heterozygote (P < 0.02) and IFNγ+874 AA (P < 0.001) genotype and leprosy. TNFα-308GA could not establish any association with the disease.

Conclusion:

The identification of genetic variations in pro- and antiinflammatory cytokines that are susceptible to leprosy would assist in better understanding of the pathogenesis of leprosy and perhaps lead to new approaches for diagnosis and treatment.
Sphenoid sinus fungall ball: a retrospective study over a 10- year period
Authors: Eloy Ph , Grenier J. , Pirlet A. , Poirrier A.L. , Stephens J.S. , Rombaux Ph
Published: June 2021

A fungal ball consists of a dense conglomerate of fungal hyphae growing at the surface of the sinus mucosa without tissue infiltration. The maxillary sinus is by far the most commonly involved paranasal sinus cavity followed by the sphenoid sinus. The present study is a retrospective study of 25 consecutive cases treated during the last 10 years in the two hospitals be- longing to the Catholic University of Louvain (CHU Mont-Godinne and UCL Saint Luc). We report the symptomatology, the imaging and discuss the different surgical managements. We conclude that the clinician must have a high index of suspicion when dealing with a unilateral rhinosinusitis persisting despite a maximal and well conducted medical treatment. This is particularly so in elderly women when associated with facial pain and post nasal drip, particularly when the computed tomography shows an unilateral opacity of the sphenoid sinus with or without a sclerosis or an erosion of the bony walls, a polyp in the sphenoethmoidal recess or a hyperdensity mimicking a foreign body. An endonasal endoscopic sphenoidotomy is the treatment of choice in most cases, allowing good ventilation of the sinus and radical removal of all the fungal concretion. A biopsy of the sinus mucosa adjacent to fungal elements is of upmost important to confirm the non- invasiveness of the fungi within the tissue. Antifungal medication is not required in uncomplicated forms. All host factors producing some degree of immunosuppression must be corrected when present and must alert the clinician to rule out any forms of invasive disease.
Wyzwania mariologii XXI wieku
Authors: Gilski Marek
Published: June 2021

Challenges of Mariology in the 21st Century

The purpose of this article is to point out the most important challenges facing Mariology in the 21st century. The text consists of five parts. It presents the Mother of the Lord in the context of: transcendentals, the struggle for a culture of life, inspiration from the Bible, cultural differences, and informatization.

Abstrakt

Celem artykułu jest wskazanie najważniejszych wyzwań stojących przed mariologią XXI wieku. Tekst składa się z pięciu części. Prezentuje Matkę Pana w kontekście: transcendentaliów, zmagań o kulturę życia, inspiracji płynących z Biblii, różnic kulturowych oraz informatyzacji.
A dimensão Pentecostal da representação parlamentar na Baixada Fluminense/RJ
Authors: Rodolfo Gilberto Polastreli
Published: June 2021

Inserido num contexto de notável conservadorismo político e religioso no Brasil atual que marca o governo de Jair Bolsonaro, o presente artigo põe em debate o avanço de um ativismo evangélico/pentecostal como força constitutiva de poder político na representação parlamentar da Baixada Fluminense/RJ. O exame quantitativo e qualitativo das leis foi a metodologia empregada para descortinar o imbricamento explícito entre política e religião na consecução de uma representação parlamentar direcionada à consolidação de uma "consciência" evangélica estruturadora da sociedade e do território da região de estudo.
Evaluarea formativă la ora de istorie, valorificând literatura artistică
Authors: Molcosean Alexandru
Published: June 2021

In this article is approach the subject of the formative assessment in the history lessons through the artistic literature. We aim to analyze the normative acts that governing the evaluation process in the general education and to subsequently offer a series of works of art that address a certain historical period. The reason why we resorted to this approach is to encourage the reading process among the students while helping them to better understand historical events and processes. Towards the end, we offer an example of composing an evaluation tasks based on a work of art.
Reconsiderarea managementului școlii de arte A. Stârcea”, mun. Chișinău, din perspectiva pedagogiei competențelor
Authors: Mîndrescu Iulia
Published: June 2021

The article addresses the opportunity of reconsidering the management of the art school nowadays, the reconceptualization of the designing-planning-organizational process and the development of the educational process from the perspective of the macro-structural and micro-structural competences, integrated in the Project of the pedagogical aims from the instrumental-artistic education perspective vis-à-vis the education plan, designing a Model for learning the basic instrumental-artistic competences with their respective specification.
The Embodiment of Discovery: An Adapted Framework for Qualitative Analysis of Lived Experiences
Authors:   Lakeside Endocrine Associates, Hernandez Helen , Dringus Laurie ,   Nova Southeastern University
Published: June 2021

We reflect on our process of working with an adapted framework as an effective strategy for analyzing and interpreting the results of our qualitative study on the lived experiences of insulin pump trainers. Interpretative Phenomenological Analysis (IPA) was applied as the overarching research methodology and was encapsulated into a framework adapted from Bonello and Meehan (2019) and from Chong (2019). We describe this framework as the “embodiment of discovery” to posit the researcher’s tangible experience of discovering the meaning of data that also brought transparency to the researcher’s process for data analysis and interpretation. We present challenges the doctoral student researcher experienced working with the framework through three phases and various steps performed during the analysis. We recommend the framework may assist novice researchers as a tool for wayfinding and scoping the structure of data analysis and interpretation. We conclude that novice researchers should not fear finding their “embodiment of discovery” in adapting creative or alternate methods for qualitative analysis.
Os Direitos Humanos e os Catadores de Materiais Recicláveis
Authors: Oliveira Tatiane de ,   Tatiane de Oliveira, Bunchaft Antonio , Cruz Uilmer Rodrigues Xavier , Bunchaft Alexandra Flávio , Regis Adherbal de Almeida , Nicolau Carlos H. , Cavalcanti Carlos Alencastro , Reis Roberval Prates ,   Antonio Bunchaft,   Adherbal de A. Reis,   Alexandra Flávio Bunchaft,   Uilmer Rodrigues Xavier da Cruz,   Carlos H. Nicolau,   Carlos Alencastro Cavalcanti,   Roberval Prates Reis
Published: June 2021

A história dos catadores e catadoras no Brasil sempre foi de muita luta! Desde 2001 com a criação do nosso Movimento Nacional dos Catadores de Materiais Recicláveis – MNCR, a luta se fortaleceu ainda mais, aumentando o reconhecimento do trabalho dos catadores por parte da sociedade e do poder público. A luta por reconhecimento do nosso trabalho e por melhores condições vida, sempre encontrou muitas barreiras. Isto coloca para nós, catadores e catadoras da coleta de materiais recicláveis, a necessidade de estudar e refletir sobre como vivenciamos no cotidiano as formas de opressão que estamos submetidos há tantos e tantos tempos.
Sarcoma de kaposi pulmonar en un paciente con sida, reporte de caso
Authors: Del Cisne Román Zambrano María , Tatiana López Bravo Marcela , Estefanía Mejía Suarez Eliana , Del Rocío Ortega García Ivonne , Victoria Peña Armijos Madeleyne , Adrián Ortiz Cumbe José , Ismael Alvarado Maldonado Danny , Alcides Valarezo Concha Cledy
Published: June 2021

El Sarcoma de Kaposi (KS) es una neoplasia maligna del endotelio vascular que se asocia con infección por el Herpes Virus tipo 8 (HHV-8) (Lodi S, 2010). La mayoría de casos de KS que presentan afectación pulmonar se acompañan con presentación mucocutánea (80 – 90% de casos) (Haramati LB, 2000) .Es más frecuente en el sexo masculino, y en pacientes inmunocomprometidos (Onak Kandemir N, 2013), (Jiménez F, 2011)

El objetivo de nuestra investigación fue realizar un reporte de caso de Sarcoma de Kaposi Pulmonar en un paciente con SIDA, utilizando como Metodología: la historia clínica completa del paciente, los estudios complementarios, incluyendo los invasivos como la fibrobroncoscopia, Biopsia de piel, que fueron de gran importancia para llegar a la etiología de la enfermedad.

A continuación, se presenta el caso clínico de un paciente masculino de 22 años de reciente diagnóstico de SIDA que presentó lesiones cutáneas induradas papulosas de coloración rojo vinosas acompañado de sintomatología respiratoria.
Anais do V International Workshop on Rational Use of Medicines.
Authors: Lopes Luciane Cruz
Published: June 2021

Producing and sharing knowledge have been the main goals of the Graduate Program in Pharmaceutical Sciences of the University of Sorocaba. With a focus on the rational use of medicines, the importance of the event is justified by highlighting one of the main concerns worldwide, with an important impact on society, health systems, institutions, and communities. The improvement of professional practices depends on the engagement of researchers, health professionals, managers, students, and others interested in improving health policies, programs, services, and actions. Developing and applying scientific methods in producing and using the best evidence is the path we have chosen. Therefore, everyone was invited to discuss relevant topics in this field of knowledge, including Drug Utilization Research; Health Technology Assessment; Global Health Systems and Environment; and Innovation and Development of Health Technologies. Experts from several countries in deprescribing, interactive teaching approaches, implementation science and policy, environment and pharmaceutical care joined us sharing their experiences and encouraging debate. We are sure that the social distancing, essential in this period, did not represent an obstacle in making new connections, and effective and bright collaborations that are able to transform reality
Proceedings V International Workshop on Rational Use of Medicines; III Worknowledge of Evidence-Informed Police; III Symposium ISPE BrazIntRIG; I Symposium of ISPE Brazilian Student Chapters
Authors:   Luciane Cruz Lopes
Published: June 2021

Producing and sharing knowledge have been the main goals of the Graduate Program in Pharmaceutical Sciences of the University of Sorocaba. With a focus on the rational use of medicines, the importance of the event is justified by highlighting one of the main concerns worldwide, with an important impact on society, health systems, institutions, and communities. The improvement of professional practices depends on the engagement of researchers, health professionals, managers, students, and others interested in improving health policies, programs, services, and actions. Developing and applying scientific methods in producing and using the best evidence is the path we have chosen. Therefore, everyone was invited to discuss relevant topics in this field of knowledge, including Drug Utilization Research; Health Technology Assessment; Global Health Systems and Environment; and Innovation and Development of Health Technologies. Experts from several countries in deprescribing, interactive teaching approaches, implementation science and policy, environment and pharmaceutical care joined us sharing their experiences and encouraging debate. We are sure that the social distancing, essential in this period, did not represent an obstacle in making new connections, and effective and bright collaborations that are able to transform reality.
An Identification and Classification of Thyroid Diseases Using Deep Learning Methodology
Authors: Nageswari C. Shobana , Kumar M.N. Vimal , Raveena C. , Sharma J. Sostika , Devi M. Yasodha
Published: June 2021

The thyroid is one of the most important parts of our body. As part of the endocrine system, this tiny gland in our neck releases thyroid hormone, which is responsible for directing all your metabolic functions which means controlling everything from digestion to conversion to energy. When thyroid dysfunction, it can affect all aspects of our health. Both researchers and doctors face challenges in fighting thyroid disease. In that thyroid disease is a major cause of the emergence of medical diagnostics and prognosis, the beginning of which is a difficult confirmation in medical research. Thyroid hormones are suspected to regulate metabolism. Hyperthyroidism and hypothyroidism are one of the two most common thyroid diseases that release thyroid hormones to regulate the rate of digestion. Early detection of thyroid disease is a major factor in saving many lives. Frequently, visual tests and hand techniques are used for these types of diagnostic thyroid diseases. This manual interpretation of medical images requires the use of time and is highly affected by errors. This work is developed to successfully diagnose and detect the presence of five different thyroid diseases such as Hyperthyroidism, Hypothyroidism, Thyroid cancer, thyroid gland, Thyroiditis and general thyroid screening without the need for several consultations. This leads to predictable disease progression and allows us to take immediate steps to avoid further consequences in an effective and cost-effective way to avoid the human error rate. A web application will also be developed where a scanned image of the inclusion will provide the removal of the most time-consuming thyroid type and patient investment.
An Efficient Damage Relief System based on Image Processing and Deep Learning Techniques
Authors: Kanya Dr.N. , Rani Dr. Pacha Shobha , Geetha Dr.S. , Rajkumar Dr.M. , Sandhiya G.
Published: June 2021

The Unmanned Aerial Vehicle (UAV) has been around for a long time but has been widely used recently by humans. Their acceptance of various communications-based applications is expected to improve coverage, compared to traditional ground-based solutions. In this paper, the Deep-learning and Image Processing Process framework is expected to provide solutions to the various problems already identified when UAVs are used for communication purposes. UAVs are used in disaster relief because of their accessibility even in inaccessible places. In this paper, we propose research into Deep learning and Image Processing strategies for UAVs. In deep learning is a form of machine learning that teaches computers to do what comes naturally to people: learn by example and get a lot of attention recently and for a good reason. It achieves previously impossible results. Image processing is the process of performing a specific task on an image, finding an enhanced image or extracting useful information from it. So our paper has the idea of using in depth face recognition and photo processing a digital photo taken by the UAV to identify victims of rescue, overcoming back to the latest UAV technology some of which include blurry images, unable to identify the victim when there are too many objects and much more. The solution includes a variety of features that allow for the distribution of images. It includes features and presentation of image detection and demonstrates the effectiveness of drone use in damage applications.
Educação Física escolar em tempos de pandemia: O trabalho em uma escola com jogos e brincadeiras tradicionais durante o Regime Especial de Atividades não Presenciais na rede estadual de ensino de Minas Gerais
Authors: Ribeiro França Filipe Gabriel , De Freitas Gomes Luciana
Published: June 2021

O presente trabalho tem como objetivo relatar as experiências desenvolvidas pelo componente curricular Educação Física com os jogos e brincadeiras tradicionais durante o regime especial de atividades não presenciais proposto pela rede estadual de ensino de Minas Gerais. As experiências relatadas foram vivenciadas nas aulas de Educação Física por turmas dos Anos Iniciais do Ensino Fundamental em uma escola pública estadual na cidade de Juiz de Fora – MG. Em diálogo com os estudantes e responsáveis foram apresentadas propostas de jogos e brincadeiras tradicionais que pudessem ser realizados em casa, tendo em vista o contexto de isolamento social decorrente da pandemia de Covid-19 ocorrido no ano escolar de 2020. As atividades sugeridas levaram em consideração a possibilidade a adaptação do espaço para as suas vivências e a construção de materiais alternativos e adaptados com recursos presentes em casa quando necessário. Metodologicamente tomamos os jogos e brincadeiras tradicionais como um dos saberes que devem ser trabalhados nas aulas de Educação Física escolar, ressaltando a importância de observarmos a cultura popular presente no contexto regional e comunitário, assumindo-a enquanto construção cultural, histórico e social. Nessa abordagem sobre os jogos e brincadeiras tradicionais os estudantes foram capazes de se expressarem conscientemente e realizarem reflexões críticas sobre como as práticas eram vivenciadas no passado e na atualidade e puderam compreender a importância do movimento e da continuidade das atividades Educação Física escolar mesmo à distância.
In Pursuit of Excellence: Student-Athlete Achievers' Motivations, Opportunities, and Struggles
Authors: Santillan Nanette L. , Madrigal Dennis V.
Published: June 2021

Twenty-first-century education recognizes the role of sports as one framework for life-long skills, values, health, and well-being. The purpose of the study was to explore the on and off-field experiences of the six Junior High School student-athletes, the driving forces associated with their participation, and its influences and contribution to their excellent performance both in academics and in sports. This study utilized the qualitative research design using the phenomenological approach to gather insights into the lived experiences of the participants. The recursive textual data analysis revealed five core themes and the essence of the phenomenon: Motivated to Excel, Strong Support System, Rewarding Opportunities, Surpassed the Hurdles, and Exercised Self-Regulation. The themes revealed that the participants highly valued the positive impact of their sports involvement and the support of significant persons in their life. The findings implied that a comprehensive understanding of the intrinsic and extrinsic motivations of the student-athletes, their self-regulation skill, and support system facilitated a more effective approach in providing a nurturing learning environment that enhances academic performance, sports skills, and holistic health.