bluuebunny/crossref_metadata_2025 huggingface dataset:
Project Control Strategies for Sustainable Project Management: focusing on the road flooding prevention case project
Authors:   Korean Institute of Smart Media, Choi Jiyeong , Song Jiyoung
Published: November 2024

As environmental pollution, energy depletion, and maintenance difficulties due to changes in social requirements arise during project progress, interest in the sustainability of project management has increased. Accordingly, sustainable project management theories have been proposed to complement the short-term goal-focused approach and performance evaluation methods that existing project management methods have adhered to. However, the sustainable project management theories have not been extended to empirical research. In this paper, we provides a case study of a sustainable project management framework and control mechanisms such as a collaboration model and incentive model using a road flood prevention project as an example. The case project was a project for improving urban infrastructure and was carried out with consideration for environmental, social, and economic sustainability. Through sustainable project management, the case project was able to achieve its sustainability goals and shows the results of the application of the control mechanisms.
A Study on Time Series Models for Predicting Cucumber Shipment Using Smart Farm Data
Authors:   Korean Institute of Smart Media, Lee Hye Kyung , Shin Changsun
Published: November 2024

This study utilizes data collected by the Rural Development Administration from smart farm sites to identify key variables affecting cucumber shipment and proposes the most accurate prediction model through comparative analysis of various forecasting models. The dataset includes daily weather conditions, cultivation environments, and management activities from 36 different crop seasons. The predictive models used in this study include Multiple Regression, ARIMA(Auto Regressive Integrated Moving Average), LSTM(Long Short-Term Memory), and SARIMA(Seasonal Auto Regressive Integrated Moving Average). Model performance was evaluated using RMSE and MAE, with SARIMA demonstrating the best results. By optimizing the hyperparameters, SARIMA's prediction accuracy improved significantly, effectively capturing the strong seasonality in cucumber shipments.
ARTIFICIAL INTELLIGENCE DAN IMPLIKASINYA TERHADAP PENGKAJIAN STUDI ISLAM PADA GENERASI Z
Authors: Al Hamidi Muhammad Fauzi , Fitriyah Alfina Wildatul , Yaturrochmah Naili , Istiqomah Fina Zaidatul , Putra Metria Dicky
Published: November 2024

Penelitian ini bertujuan untuk mengetahui dampak penggunaan teknologi AI, penggunaan teknologi AI, dan kendala yang timbul dalam penggunaan teknologi AI sebagai sarana pembelajaran agama Islam bagi generasi Z. Penelitian ini bersifat deskriptif kualitatif dengan jenis studi kepustakaan. Sumber data utama diperoleh dari data pustaka dan sumber data pendukung diperoleh dari hasil angket pada generasi Z. Teknik pengumpulan data menggunakan teknik dokumentasi dan angket serta dianalisis dengan model analisis  Mels dan Huberman meliputi reduksi data, penyajian hasil reduksi, dan penyajian kesimpulan. Hasil penelitian ini menunjukkan bahwa teknologi AI telah menjadi topik penelitian terbaru dan dikaji dalam berbagai aspek antara lain. Penggunaan teknologi artificial intelligence (AI) dalam mempelajari kajian Islam secara digital memiliki dampak kualitas terhadap kehidupan spiritual generasi Z. Penggunaan teknologi AI dalam pembelajaran agama Islam bukan sebagai sumber rujukan utama, melainkan sebagai sarana pendukung, alat bantu. Kendala dalam penggunaan teknologi AI meliputi kendala internal dimana generasi Z menjadi ketergantungan pada teknologi dan kendala eksternal seperti kurangnya keakuratan informasi agama dan keterbatasan akses teknologi. Kendala tersebut perlu diperhatikan demi menunjang proses pembelajaran agama Islam pada generasi Z.
SCIENCE LEARNING MEDIA: ANALYSIS OF UTILIZATION IN CLASS V MI AL MUBAROK
Authors: Hikmatul Immayanti  , Putri Ika Cahyani  , Nurhaningtyas Agustin
Published: November 2024

Learning media are tools or intermediaries used by teachers to channel information to students so that learning objectives are achieved. If we look at the facts on the ground, learning media has its own advantages and challenges in improving the quality of learning, especially at MI. Teachers are required to carry out learning using media, but on the other hand, they face many obstacles such as inadequate facilities and infrastructure. This condition makes teachers have to rack their brains with their abilities and creativity together with students to create alternative media so that the use of media is appropriate and not a barrier to learning. This research aims to analyze the use of learning media and the problems of using science learning media in class V as well as efforts to overcome these problems. This research was conducted at MI Al Mubarok Semanding. This research uses a qualitative approach with a case study type of research. Namely focused on learning media analysis. Data collection techniques include observation, interviews and documentation. The results of this research show that teachers are able to face the challenges of technological limitations by creating alternative media with students. However, schools are also trying to fulfill the provision of technology-based media by running a one day one coin program so that learning is more effective and efficient.
Study of algorithms for optimization of energy management in transportation systems for reduction of environmental impact
Authors: Shemrikovych Anhelina , Samantsov Оleksandr , Nazarov Oleksii , Nazarova Nataliia
Published: November 2024

The object of the research is the technology of optimization algorithms for energy consumption management in transport systems. The purpose of the work is research and analysis of the effectiveness of optimization algorithms for reducing environmental impact, selection of criteria and methods for comparative analysis. The existing algorithms for optimizing energy consumption management in transport systems were considered, their advantages and disadvantages and principles of operation were investigated, methods of comparison were described and demonstrated, and formulas for calculating numerical indicators were proposed.
Improvement of the secure routing model in software-configured networks
Authors: Pliekhova G. А. , Neronov S. М. , Kostikova М. V. , Kashkevich S. O.
Published: November 2024

Currently, the deployment of such network architectures as Software-Defined Networking (SDN) is facing new cyber security threats that require the development and research of new specialized solutions to increase the level of network security. Despite its high openness and programmability, the SDN architecture replaces the traditional network, but it increases the number of potential network attacks, which leads to new security problems.
The growing interest in SDN and the widespread deployment of software-configured networks of various types allow identifying their shortcomings in the process of combating cyber security threats. Obviously, security issues are closely related to the characteristics of SDN networks themselves. Furthermore, security issues in SDN can be divided based on three layers: data plane, control plane, and application plane.
At the same time, devices of different SDN levels can be among the objects of attacks. Therefore, according to the multilayer architecture of SDN, security threats can be classified at the data transmission, management and application layers. For its part, the data plane consists of switches and other network devices and is mainly responsible for data processing, forwarding, discarding, and collecting statistics. The data plane functions on the basis of flow rules provided by the network controller. While the main causes of security problems are the SDN architecture itself, external malicious attacks, insufficient access control and encryption tools.
Today, an important place in the complex of means of increasing network security, including SDN networks, is given to routing protocols, which require the systematic and coordinated interaction of a number of network elements at the same time – SDN switches and network controllers during the formation (calculation) of paths and flow rules, along which the required level of security must be ensured according to selected indicators or criteria.
The paper analyzes how to modify route metrics in such a way that the resulting model acquires the properties of secure QoS routing. It is shown that the improvement of the model and the choice of the route should be chosen taking into account the basic metrics of the criticality of vulnerabilities and the bandwidth of the communication channels that make up this route.
Roles of Individual Institutions in Achieving Pharmaceutical Sovereignty as Exemplified by the Medical Technology Transfer Centre of the Scientific Centre for Expert Evaluation of Medicinal Products
Authors: Koshevenko A. S. , Degrave T. V. , Burenkov P. V. , Belanov K. Yu. , Kosenko V. V.
Published: November 2024

INTRODUCTION. The strengthening of the health system and the improvement of access to medicines directly depend on the development and marketing authorisation of national innovative medicinal products. Technology transfer is a key tool in bringing medicinal products to market.

AIM. This study aimed to evaluate the role of the Medical Technology Transfer Centre of the Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) in facilitating the implementation of federal projects in medical science and in achieving of pharmaceutical sovereignty.

DISCUSSION. This article is an overview of the main trends in and features of the development of the pharmaceutical industry in the Russian Federation and around the world. The article highlights significant federal decisions made to attain pharmaceutical sovereignty and improve access to medicines for the population. The authors consider documents regulating the work of the Medical Technology Transfer Centre and outline its roles and responsibilities. Additionally, the authors analyse the ability of the Medical Technology Transfer Centre to provide project support throughout the medicinal product development process and to address issues pertaining to efficient pharmaceutical development, patent law, and product commercialisation. The article assesses the role of the Medical Technology Transfer Centre in the development of the pharmaceutical industry in the Russian Federation.

CONCLUSIONS. The Medical Technology Transfer Centre supports projects as part of efforts to implement federal projects in human medical science. The Medical Technology Transfer Centre can be considered a driver of effective innovative development in the national pharmaceutical industry.
Elements of Strategic Planning of Patent Protection for Pharmaceutical Inventions
Authors: Anikeeva M. Yu. , Gorbunova Yu. A. , Pikina N. A.
Published: November 2024

INTRODUCTION. The commercial success of innovations in medicine and pharmaceutics depends on the strategic planning of patent protection, with the main elements for consideration being the type of patent protection, the scope of the invention, and the order of obtaining protection documents.

AIM. This study aimed to analyse specific aspects of the strategic planning of patent protection for pharmaceutical inventions.

MATERIALS AND METHODS. The study applied analysis and comparison methods to patent information. Statistical data were prepared using patent databases, including the Rospatent search platform and Questel.

RESULTS. In the Russian Federation, invention patents for methods of treatment and diagnosis are more abundant than pharmaceutical product patents. The most reasonable method for protecting intellectual property rights in the pharmaceutical industry is the stepwise obtaining of different types of protection documents for different objects of patent protection, including inventions, utility models, and industrial designs, as part of one project. The strategy of patent protection for a pharmaceutical invention should consider the type of patent (protection combining the use of patents for inventions, utility models, and industrial designs), the correct determination of the object of patent protection (obtaining a product (substance) patent), and stepwise obtaining and strategic accumulation of different protection documents.

CONCLUSION. The described strategy helps to cover the fullest possible range of rights protection options, prevent patent infringement, and extend the patent protection period for an invention.
Kinetic Bacterial Endotoxin Testing Methods: Specifics of Analytical Conditions Exemplified by Medicinal Products from Different Classes
Authors: Shapovalova О. V. , Neugodova N. P. , Sapozhnikova G. A.
Published: November 2024

INTRODUCTION. Kinetic bacterial endotoxin (BE) testing methods based on amoebocyte lysate from the haemolymph of the horseshoe crab can quantify BEs in parenteral medicinal products across a broad range of concentrations. To develop a specific analytical procedure that is based on these methods and can be implemented into pharmaceutical quality control and standardisation, it is required to ascertain the conditions for its use, in particular, to determine the lowest product dilution that would neutralise interfering factors.

AIM. This study aimed to develop an analytical procedure for the quantitative determination of BEs by the kinetic chromogenic method.

MATERIALS AND METHODS. The study examined samples of medicinal products containing active substances from different classes, including a monoclonal antibody (mepolizumab) and a direct-acting anticoagulant (nadroparin). The BE limits for mepolizumab and nadroparin were ≤20 EU/mL and ≤95 EU/mL, respectively. The samples were tested at different dilutions, which did not exceed the maximum valid dilution. The measurements were performed using a BioТek EL×800 photocolourimeter and EndoScan-V software.

RESULTS. The results for mepolizumab samples show that the kinetic chromogenic method can quantify BEs in mepolizumab medicinal products in the dilution range of 1:10 to 1:40. The study detected BEs in quantities of 0.0078–0.224 EU/mL within this dilution range. However, at a dilution ratio of 1:50 or higher, the method is suitable only for qualitative BE tests. For nadroparin medicinal products, the quantitative determination of BEs should start at a dilution of 1:1000 (the study demonstrated no influence of interfering factors at this dilution).

CONCLUSIONS. The authors developed analytical procedures for the determination of BEs in mepolizumab and nadroparin medicinal products by the kinetic chromogenic method (method D). When developing analytical procedures for the quantification of BEs in individual medicinal products, the developer should determine the lowest sample dilution that would neutralise interfering factors. Subsequently, the dilution should be specified in the documentation for the analytical procedure. This approach can enhance assay accuracy and save time and resources in routine testing.
Development and Validation of an Analytical Procedure for Determining Convallatoxin in Medicinal Products Containing Cardiac Glycosides of Lily of the Valley
Authors: Golomazova T. A. , Antonova N. P. , Semenova N. E. , Shefer E. P. , Prokhvatilova S. S.
Published: November 2024

INTRODUCTION. The safe use of lily-of-the-valley medicinal products requires adequately controlling the content of cardiac glycosides. The State Pharmacopoeia of the Russian Federation stipulates that the content of cardiac glycosides in lily-of-the-valley medicinal products should be quantified using bioassays and spectrophotometry. However, the determination of cardiac glycosides needs more accurate and selective physicochemical methods, such as high-performance liquid chromatography (HPLC).

AIM. This study aimed to develop and validate an HPLC analytical procedure for the quantitative determination of cardiac glycosides (convallatoxin) in lily-of-the-valley herbal medicinal products.

MATERIALS AND METHODS. The study examined the Lily-of-the-Valley Tincture, Zelenin Drops, Valocormid, Carniland®, and Lily-of-the-Valley Extract Reference Standard samples. The content of cardiac glycosides was determined by comparison with a reference standard for convallatoxin by HPLC and spectrophotometry. The samples were prepared as outlined in Monograph 3.4.0003.18 Lily-of-the-Valley Herb Tincture of the State Pharmacopoeia of the Russian Federation. Mixed cardiac glycosides were separated on a Luna 5 µm C18(2) column by gradient elution with 0.1% orthophosphoric acid in water and acetonitrile. The analysis was performed using an autoinjector with sample cooling to 5 °C.

RESULTS. The developed analytical procedure met the acceptance criteria for specificity, intermediate precision, linearity (correlation coefficient of 0.99985), and repeatability (relative standard deviation of convallatoxin measurements of 1.61%). The analytical procedure is suitable for the quantitative determination of convallatoxin in lily-of-the-valley herbal medicinal products because it produces reliable and repeatable results.

CONCLUSIONS. The authors developed a highly sensitive and selective HPLC analytical procedure for the quantitative determination of convallatoxin in lily-of-the-valley herbal medicinal products. The content of convallatoxin ranged from 0.012 to 0.018 mg/mL in the liquid active substance Lily-of-the-Valley Tincture, from 0.004 to 0.013 mg/mL in the medicinal product Zelenin Drops, and from 0.005 to 0.007 mg/mL in the medicinal products Carniland® and Valocormid. For the Lily-of-the-Valley Extract Reference Standard, the content of convallatoxin amounted to 0.029 mg/mL.
Experience in the Examination of Bioequivalence Clinical Trials of Locally Applied and Locally Acting Medicinal Products in Accordance with the Eurasian Economic Union Procedures
Authors: Ivanova O. Yu. , Shikhovtsova O. L.
Published: November 2024

INTRODUCTION. The examination of protocols for clinical trials of locally applied and locally acting medicinal products highlights challenges that developers face when selecting the design, endpoints, population, comparison groups, and sample size. An analysis of the most common errors in clinical trial protocols will help minimise the number of comments from protocol reviewers and accelerate the process of bringing novel medicinal products to the pharmaceutical market.

AIM. This study aimed to analyse the results of evaluating clinical trials of locally applied and locally acting medicinal products conducted with due consideration of the recent additions to the Rules for Conducting Bioequivalence Studies of Medicinal Products within the Eurasian Economic Union (EAEU); assess the main advantages of the added requirements and the challenges remaining in protocol development; and make recommendations for the most effective application of existing laws and regulations.

DISCUSSION. The Rules for Conducting Bioequivalence Studies of Medicinal Products within the EAEU were supplemented with Appendices 11, 12, and 13 in August 2023. Since then, protocol reviewers have accumulated sufficient experience in the examination of clinical trial protocols for locally applied and locally acting medicinal products. This article presents the most frequent comments made during the examination of clinical trial protocols and provides recommendations for corrective actions. The most challenging aspects of drafting a protocol for a clinical trial of a locally applied and locally acting medicinal product include the selection and justification of primary/secondary endpoints and the calculation and justification of the population size. The difficulty is probably due to the lack of a detailed description of study characteristics in EAEU laws and regulations. Locally applied and locally acting corticosteroids are the least challenging medicinal products in terms of protocol drafting because EAEU legislation and scientific publications provide the most detailed guidance for them.

CONCLUSIONS. The analysis of protocols for clinical trials of locally applied and locally acting medicinal products, relevant EAEU requirements, and applicable international guidelines identified several major challenges, including the selection of primary/secondary endpoints, the characterisation of the trial population, and the justification of the sample size. The recommendations presented in this article will help applicants in planning clinical trials aimed at accelerating the launch of medicinal products into the pharmaceutical market.
A Methodological Exploration of Document Analysis as a Qualitative Research Method
Authors:   Korean Association for Qualitative Inquiry, Ji Yeonjung
Published: November 2024

The purpose of this study is to explore the methodological characteristics of document analysis as qualitative research method. It aims to reassess the importance of document analysis in terms of methodological theorization and exploration of qualitative research in Korea, and to attempt a theoretical exploration of document analysis methods to enable more effective implementation.
To this end, the study analyzes the methodological features and procedures of representative studies utilizing document analysis, examining the types of documents used by researchers, the procedures and analytical criteria employed, and how research results were derived. The analysis revealed the following: First, various types of documents are used in qualitative research. Personal documents include diaries, letters, autobiographies, and memoirs, while public documents such as newspapers, court rulings, textbooks, curriculum documents, national education policy documents, patient records, and archives are widely used across various fields of research. Second, in qualitative research, a quantitative approaches are also used in the process of identifying frequencies or patterns. Third, methodologically, document analysis is systematically conducted through various approaches including qualitative content analysis, thematic analysis, grounded theory, and discourse analysis methods.
This study will contribute to increasing the utilization of document analysis as a qualitative research method and expanding its scope by providing qualitative researchers with a systematic methodology for document analysis.
Qualitative Meta-analysis of Counselor’s Vicarious Trauma
Authors:   Korean Association for Qualitative Inquiry, Park Aeshil , Park Altteuri
Published: November 2024

This study aims to comprehensively explore counselors’ experiences of vicarious trauma and associated factors. To achieve this, 11 qualitative studies that met specific criteria regarding coun-selor vicarious trauma were selected, and a qualitative meta-analysis was conducted. The findings can be summarized as follows: First, the counselor’s vicarious trauma experience was analyzed through five stages: exposure to client trauma, vicarious trauma experience itself, coping mech-anisms, vicarious post-traumatic growth, and decisions regarding leaving the counseling pro-fession. Counselors often exhibited symptoms similar to those of the trauma they encountered through their clients; however, many also reported personal growth as a result of coping with vi-carious trauma. Conversely, some counselors chose to leave the counseling profession when they felt unable to manage their experiences effectively. Second, factors that exacerbated the progres-sion from exposure to client trauma to vicarious trauma were categorized into client, counselor, and environmental factors, with environmental factors being more diverse in terms of subcatego-ries and content than the other two categories. Third, protective factors identified during coping with vicarious trauma and subsequent growth were also categorized into client, counselor, and en-vironmental factors, with environmental factors again showing a greater variety of subcategories and content. Drawing insights from an exploration of the meaning of counselors’ vicarious trau-ma experiences, a model of this phenomenon was developed, and its implications were discussed.
An Art-Based Narrative Inquiry into a Middle-Aged woman’s Experience in Exploring Self-Identity
Authors:   Korean Association for Qualitative Inquiry, Choi Jaesook , Koo Jagyoung
Published: November 2024

In this study, the experience and meaning of a middle-aged woman’s self-identity search were explored in a narrative based on art. The participant of this study, Kim Min-seo (pseudonym), is a woman in her 50s. The researcher and the participant conducted a total of 10 sessions from July 26, 2022, to September 27, 2022, followed by two additional interviews 9 months later. To explore the meaning of the participant’s experiences of self-identity, formed throughout her life, the researcher employed various artistic media and techniques such as clay modeling for emotional expression, drawing family figures, writing poetry, collage-making, and reading fairy tales. Through these sensory, perceptual, cognitive, and symbolic methods, the participant was encouraged to express her life story, and the researcher engaged in discussions with the participant centered around her artistic creations. Based on the verbatim transcripts of all conversations, photographs of the participant’s artistic creations, and the researcher’s journal, a narrative of the participant’s self-identity exploration experience was constructed within a three-dimensional narrative inquiry space. The meaning of the participant’s experiences was then analyzed through this process. As a result, the meaning of the participant’s self-identity exploration experience was constructed as follows: 1. Catharsis through opening up about childhood experiences of abuse. 2. Confession and reflection on guilt related to child abuse. 3. Understanding of interpersonal conflict caused by the lack of nurturing care. 4. Discovery of a new identity for the wounded inner child. Through the relational inquiry space facilitated by her artistic creations, the participant was able to unravel various self-identity narratives embedded in her experiences of both victimhood and perpetration of abuse within the family, as well as her current interpersonal conflicts. In doing so, she discovered the symbol of a “fully bloomed yellow flower,” representing a beautiful and confident version of herself.
Evaluación de un modelo de rendimiento de maní como herramienta para la planificación y el manejo del cultivo
Authors: Seiler R. A. , Vinocur M. G.
Published: November 2024

El manejo de cultivos agrícolas, así como la evaluación de las alternativas culturales más favorables, pueden ser realizados con éxito mediante modelos que simulen con precisión el sistema agrícola bajo análisis. Con el propósito de proveer un modelo para cultivo de maní, válido para esas aplicaciones, se procedió a la realización de ensayos con ese cultivo en el área de Carnerillo y de Río Cuarto, en la provincia de Córdoba (Argentina). Con los datos fenológicos, fenométricos, meteorológicos y de suelos, obtenidos de tres campañas agrícolas en cada lugar, se ajustó el modelo PNUTGRO V1.02 de maní. Las evaluaciones del comportamiento del modelo en ambos lugares geográficos mostraron una adecuada estimación de las fechas de los estados fenológicos. El rendimiento de grano en Río Cuarto fue estimado con un error de 9,6 %, mientras que en Carnerillo fue de 18,8 %. Los errores en la simulación de la biomasa del cultivo fueron mayores, llegando al 32 % en Río Cuarto y al 16 % en Carnerillo. Las bondades encontradas, principalmente en la simulación del estado del cultivo y en el rendimiento en grano, plantean el uso de este modelo como promisorio.
Endothelial dysfunction in combination of occupational pathology of the respiratory system and atherosclerosis in coal industry workers
Authors: Panev Nikolay I. , Filimonov Sergey N. , Korotenko Olga Yu. , Rumpel Olesya A.
Published: November 2024

Introduction. The increasing prevalence of cardiovascular pathology among industrial workers determines the importance of studying not only occupational diseases, but also their combination with diseases of the circulatory system. Endothelial dysfunction is a key link in the pathogenesis of atherosclerosis. Evaluation of endothelial function indicators in occupational respiratory diseases in combination with atherosclerosis in workers of the coal mining industry is an urgent task.
The study aims to consider the indicators of endothelial function in miners with occupational respiratory diseases in combination with atherosclerosis.
Materials and methods. The authors have examined 88 miners with previously diagnosed occupational respiratory diseases (chronic dust bronchitis, anthracosilicosis, chronic obstructive pulmonary disease), 45 of them showed signs of atherosclerosis. There were two comparison groups without signs of atherosclerosis: 44 miners who work long-term in harmful working conditions, without lung pathology (control group) and 42 residents of Novokuznetsk who have never worked in harmful working conditions, and without lung pathology (unexposed group).
Results. We found that miners with occupational respiratory diseases in combination with atherosclerosis had several forms of endothelial dysfunction: vasomotor (decreased synthesis of nitric oxide, increased endothelin-1 levels), hemostatic (increased levels of Willebrand factor), adhesive (increased levels of endothelial adhesion molecules sVCAM-1).
The development of respiratory insufficiency in miners with occupational respiratory diseases increases endothelial dysfunction: miners with respiratory insufficiency have lower levels of nitric oxide (NO), higher levels of endothelin-1 and endothelial adhesion molecules sVCAM-1 than miners without respiratory insufficiency. There are correlations between indicators of endothelial function and production factors: with work experience in harmful working conditions, the level of the average concentration of coal-rock dust in the workplace and the frequency of exceeding the maximum permissible concentration of coal-rock dust. Limitations. The study is limited to a sample of workers in the main professions of coal mines who were examined at the Research Institute of Complex Hygiene Problems and Occupational Diseases, aged 40 to 54 years, with more than 15 years of experience working in underground dust conditions.
Conclusion. Miners with occupational respiratory diseases in combination with atherosclerosis develop several forms of endothelial dysfunction: vasomotor, hemostatic, adhesive. The development of respiratory failure increases endothelial dysfunction.
Ethics. This medical study involving a human as a subject was carried out in compliance with the Ethical principles presented in the latest version of the Helsinki Declaration, developed by the World Medical Association.
Changes in heart rate variability and subclinical heart failure with preserved left ventricular ejection fraction in workers of the main professions at the coal industry
Authors: Martynov Ilya D. , Korotenko Olga Yu. , Filimonov Egor S. , Rumpel Olesya A.
Published: November 2024

Introduction. The high prevalence of diseases of the circulatory system necessitates their detection and prevention at an early stage, especially in regions with high industrial potential. The occurrence of subclinical heart failure depends on a cascade of processes that are already occurring in the body and may eventually manifest themselves in clinically pronounced diseases. One of the possible mechanisms of its development is a violation of the balance of the autonomic nervous system with a violation of adaptive capabilities to the labour process, characterized by severe physical overloads among miners.
The study aims to evaluate changes in heart rate variability in workers of the main professions at the coal industry with signs of heart failure with a preserved left ventricular ejection fraction.
Materials and methods. The study included 78 employees of the main professions at the coal industry. Specialists performed ultrasound examination of the heart according to generally accepted methods with the study of longitudinal deformation of the myocardium. The concentration of NT-proBNP in the blood serum was determined by solid-phase enzyme immunoassay. The authors also conducted an analysis of heart rate variability, determined temporal, spectral and linear parameters.
Results. Specialists revealed a decrease in longitudinal myocardial deformation in 38.5% of the examined patients, signs of diastolic dysfunction in 41%; in these groups, a tendency to increase the concentration of NT-proBNP was revealed. In the examined miners with heart failure with preserved ejection fraction, they revealed a significant decrease in the SDNN index and an increase in IC values. The increase in DFA and LF/HF indicators reflects a vegetative imbalance towards sympathetic activation observed in all surveyed miners.
Limitations. This study is limited to a sample of employees of the main professions of the coal industry undergoing periodic medical examination at the Research Institute of Complex Problems of Hygiene and Occupational Diseases.
Conclusion. The revealed relationship between indicators of heart failure and heart rate variability (SDNN, LF/HF, DFA and IC) in miners allows us to identify a group of people at greatest risk of adverse outcomes.
Ethics. The study was conducted in compliance with the standards of the Bioethical Committee of the Research Institute of Complex Problems of Hygiene and Occupational Diseases, established in accordance with the Helsinki Declaration of the World Medical Association "Ethical Principles of Conducting medical Research with human participation as a subject" as amended in 2013 and the "Rules of Good Clinical Practice" approved by Order No. 200n of the Ministry of Health of the Russian Federation dated 04/01/2016. The subjects signed an informed consent to participate in the study.
E-Business Online Experience, Satisfaction and Trust: Basis for Customer Loyalty among Selected SMEs in Bulacan
Authors: Pleno Allan B , Reclusado Araceli M
Published: November 2024

This research paper investigates the relationship between e-business online experience, satisfaction, and trust as predictors of customer loyalty among small and medium enterprises (SMEs) in a selected area of Bulacan. Considering the increasing reliance on digital platforms for e-commerce, issues surrounding online security and user privacy have arisen, raising concerns about consumer trust in e-business environments. Employing a quantitative research methodology, the study utilizes a quantitative descriptive and correlational design to measure and identify the mean and standard deviation of online experience, satisfaction, and trust as independent variables, with customer loyalty as the dependent variable. The findings reveal that SMEs in Bulacan have a strongly positive perception of their e-business online experience, particularly highlighting the simplicity, visual appeal, and effectiveness of the websites they use. They appreciate the quality of information provided by these e-business platforms, which facilitates e-purchases through up-to-date content and straightforward transactions. The study also indicates a strong agreement among SMEs regarding the effectiveness of e-business websites in meeting consumer expectations for repeat purchases, while also identifying areas for improvement in online performance features. Moreover, SMEs generally perceive a high level of security regarding e-business platforms, particularly regarding information transmission and electronic payment safety. However, there was a slightly lower perception of user privacy concerns. The regression analysis indicates that both e-business online experience and customer satisfaction are significant predictors of customer loyalty, underscoring the importance of enhancing these aspects to cultivate lasting customer relationships.
Introducing the Null Faculty into Liberal Education: where Dewey and Piaget are realized
Authors: Panarello Christian
Published: November 2024

Although we are very often taken to pass judgment on such abstract topics as “teacher quality” and “classroom environments”, the Liberal Education that much of the Western World has been engaged in is predicated on a thus introduced “Null Faculty” – the teaching is far more approximate to a cultist and reduced behavior otherwise unknown to recognisable forms of intellectualism. Dewey and Piaget have introduced principled ideas that this intentionally brief – and therefore accessible – text has covered in tandem with its own principles.
Political Debates and the Integration of Ukrainian Refugees in Germany
Authors: Hilbig Hanno , Sichart Florian , Syunyaev Georgiy
Published: November 2024

Following Russia’s full-scale invasion of Ukraine, the EU and its member states allocated over €33 billion in military aid to Ukraine, sparking widespread debates about the appropriate level of support. Do these debates affect how Ukrainian refugees in Europe perceive their host countries? To investigate this question, we conducted a survey experiment among Ukrainian refugees in Germany. We exposed participants to authentic statements from German politicians either supporting or opposing increased military aid to Ukraine. Although exposure to opposition statements shifted refugees’ perceptions of Germany’s military support as intended, it did not significantly affect their overall views of Germany’s support for Ukrainian refugees, their sense of belonging, or their intentions to return to Ukraine. Further analysis indicates these null effects are not driven by refugees’ prior attitudes toward the conflict, levels of prior integration, or previous exposure to such debates. These findings suggest that even contentious political debates about supporting refugees’ country of origin may have little impact on refugees’ perceptions of integration into host countries. Our study contributes to a broader understanding of refugee integration processes and their relation to political discourse.
Eliminating Disparate Impact in Modeling
Authors: Tom Daniel M.
Published: November 2024

There is considerable regulatory oversight on credit lending. Besides having to perform well predicting credit defaults, a credit model also needs to be explainable and non-discriminatory on protected demographics. A regression model neutralization technique eliminates disparate impact discrimination. We use it in our Logistic Regression with classic AI Beam Search, so our model meets these criteria. In contrast, the adversarial debiasing methodology has shortcomings, which we discuss.
Regional screening of saline aquifers in the Malay Basin for CO2 storage
Authors: de Jonge-Anderson Iain , Ramachandran Hariharan , Widyanita Ana , Busch Andreas , Doster Florian , Nicholson Uisdean
Published: November 2024

The Malay Basin has received significant attention for geological carbon dioxide storage (GCS), but there are no published studies addressing the selection of appropriate deep saline aquifers. This study closes this gap. We process spatial data and use geological modelling and cluster analysis to identify optimal areas for GCS, considering various subsurface characteristics such as temperature, pressure, porosity and thermophysical CO2 properties. It is found that the basin contains numerous Cenozoic aquifers suitable for GCS including locally thick, but low net-to-gross (NTG), stacked formations. Pliocene aquifers are too shallow to contain CO2 in large quantities, but upper Miocene aquifers located in the northwest of the basin contain promising intervals with significant porosities and conditions favouring denser CO2. Middle Miocene aquifers, while low NTG, are thick, and optimally located around the margins of the basin. They also have significant storage capacity and could be developed as a stacked GCS site. Lower Miocene aquifers are higher NTG, but deeply buried across many areas of the basin, yet the oldest aquifer evaluated still holds substantial storage capacity, where subject to minor burial at the margins of the basin. Overall, this study provides a novel first assessment of aquifer GCS potential in the Malay Basin, while also contributing to wider efforts to evolve screening workflows for rollout to other geological basins.
Unravelling sustainable development at the sub-national scale in India
Authors: Garai Nandini , Roy Ajishnu , Pramanick Kousik
Published: November 2024

India's diverse socioeconomic landscape and environmental challenges make it a complex case for implementing the UN Sustainable Development Goals (SDGs). Despite India's federal structure, comprehensive research on subnational SDG progress is lacking. This study analysed progress, challenges, interlinkages, and spatial disparities in individual and grouped SDGs (environmental, social, and economic) across 37 Indian states and union territories (UTs). We employed a multi-method approach to analyse the SDGs across 112 indicators (2018-2020). Significant variations in SDG performance across India, with the southern and northern states generally outperforming the central and eastern states. Inequality showed decreasing trends in most SDG groups, indicating progress towards a more equitable distribution of SDG achievements. This study provides a comprehensive baseline for tracking the progress of the SDGs in India. Based on the results of this study, tailored context-specific suggestions for policymakers were proposed that integrate environmental, social, and economic priorities. Promoting inter-state collaboration, strengthening institutions, and data-driven decision-making are crucial for accelerating India's progress towards ambitious SDGs.
Could some forms of psychological adversity be a blessing in disguise?
Authors: Maturlu Noel
Published: November 2024

Spirituality has been described as an ambivalent experience. On the one hand, due to its soothing affective potential, spirituality has been lauded by medical science as the most protective factor against depression and other mental disorders. On the other hand, however, spirituality can lead to spiritual emergencies and other mental disorders. This paper provides scientific explanation to the ambivalent nature of spirituality and why spiritual emergencies and other mental disorders can be a blessing in disguise as they can significantly increase the possibility of spiritual growth and a more robust mental wellbeing. Implications for mental health practice is also discussed.
Intensive Short-Term Dynamic Psychotherapy for depression: Treatment effectiveness and effects of unlocking the unconscious
Authors: Johansson Robert , Eriksson Kajsa , Åberg Kalle , Town Joel , Abbass Allan
Published: November 2024

Intensive Short-Term Dynamic Psychotherapy (ISTDP) has an increasing amount of evidence regarding its efficacy across various psychiatric conditions and specifically with depression. The aim of this study is to replicate the findings of controlled research by examining the effects of ISTDP in the treatment of depression in a large naturalistic sample, and also to explore the mediating role of unlocking the unconscious in this treatment. Healthcare costs were also explored. Data were collected from a naturalistic study conducted at the Centre for Emotions and Health, Halifax, Nova Scotia, Canada, between 1999 and 2007. A sample of 195 patients' self-reported levels of depression, measured by the depression subscale of the Brief Symptom Inventory (BSI), and interpersonal problems, measured by the Inventory of Interpersonal Problems-32 (IIP-32), were analyzed using mixed-effects models. The analysis revealed a significant and large effect of ISTDP on both depression (within-group Cohen's d = 1.02, 95% CI [0.75, 1.26]) and interpersonal problems (within-group Cohen's d = 1.17, 95% CI [0.89, 1.46]). The process of unlocking the unconscious emerged as a significant mediator of treatment outcomes for both depression (between-group Cohen’s d = 0.60, 95% CI [0.16, 1.07]) and interpersonal problems (between-group Cohen’s d = 0.47, 95% CI [-0.05, 0.95]). Reductions in costs regarding physician (p = 0.07) and hospital costs (p < 0.05) were observed. These findings support the efficacy of ISTDP in treating depression and highlight the importance of unlocking the unconscious among patients with depression.
Digital Artistry: Exploring Techniques and Trends in Indian Art and Culture
Authors: Singh Khushboo
Published: November 2024

From prehistoric cave paintings to contemporary digital creations, art has been integral to human expression throughout history.  Digital art in modern art gradually includes various forms, such as Painting, sculpture and animation, using technology as its medium. Digital art includes any artistic work using digital technology, including Painting, 3D modelling, and interactive installations. It combines human creativity with computer technology, expanding the possibilities of creative expression. Studying digital artistry in India provides insights into cultural preservation, technological innovation, and social commentary. It promotes educational development and economic opportunities, contributing to the country's vibrant artistic scene. Technological advancements have democratized digital art creation in India, leading to diverse artistic expressions. Integrating digital art with emerging technologies like AR, VR, and NFTs opens up new possibilities for artistic exploration and dissemination. Digital art techniques include digital Painting, vector art, and 3D modelling, facilitated by hardware such as graphics tablets and software such as Adobe Creative Cloud. Brushes, textures and plugins enhance the creative process, while photo manipulation and 3D sculpting provide new avenues for artistic expression. Digital artistry in India offers insights into cultural dynamism, technological innovation and artistic development. This research paper delves into the evolving landscape of digital artistry in India, exploring various techniques, trends, and the socio-cultural impact of digital art in the country.
Empirical Legal Analysis of Land Rights Dispute Resolution between Indigenous Communities and Mandalika Special Economic Zone Development Companies
Authors: Fathin Lalu Ammar , Arba  , Putro Widodo Dwi
Published: November 2024

This study aims to analyze the implementation of the settlement of land rights disputes between indigenous peoples and special economic zone development companies. Mandalika, as well as factors that influence the resolution of land rights disputes between indigenous peoples and Special Economic Zone development companies. Mandalika. Using empirical legal research methods. The results of this study indicate that the settlement process in the dispute resolution process, there are 2 dispute resolution processes, namely: Settlement through Non-Litigation and Litigation. Settlement of disputes outside the court or known as Alternative Dispute Resolution can be achieved through Arbitration, Mediation, Conciliation, Minitrial, Summary Jury Trial, and Settlement Conference. While the settlement through litigation on customary land as a dispute resolution between parties is carried out through examination before a judge in a court institution, this is because the development of the era towards the needs of the community for justice and welfare is increasing. Factors that influence the settlement of disputes over land rights between customary law communities and the Mandalika special economic zone development company, namely: legal factors and intervention of the authorities, cultural factors, socio-economic factors, and factors of third party involvement. In the dispute resolution process, the community emphasizes more on settlement through non-litigation, namely mediation.