bluuebunny/crossref_metadata_2025 huggingface dataset:
Gambaran Kadar Protein Urin Pada Orang Yang Mengkonsumsi Minuman Beralkohol Di Lingkar Timur Kota Bengkulu
Authors: Sari Wina Puspita , Sahidan Sahidan
Published: August 2024

Latar belakang : tuak adalah minuman yang diperoleh dari hasil fermentasi. minuman beralkohol adalah minuman yang mengangandung etanol. Etanol adalah bahan psikoaktif yang jika mengkonsumsinya dapat menurunkan kesadaran. Alkohol termasuk zat adiktif yang dapat menyebabkan rasa ketagihan adan depensi. Alkohol jika dikonsumsi secra berlebihan dapat dan terus menerus dapat menyebakan efek toksik bagi tubuh baik secara langsung maupun tidak langsung. Salah satu dampak dari konsumsi alkohol adalah adalah meningkatnya resiko gagal ginjal. Penyakit yang merusak tubulus dan gromerulli yang menyebabkan ekskresi protein-protein kecil secara berlebihan. Tujuan : untuk mengetahui gambaran protein urin pada orang yang mengkonsumsi minuman beralkohol di lingkar timur kota bengkulu. Metode : jenis penelitian yang digunakan adalah deskriptif, yaitu penelitian yang dilakukan yang dilakukan untuk menggambarkan suatu penomena yang terjadi dikalangan masyarakat. Sampel terdiri dari 30 responden dengan metode accidental sampling. Dilakukan pemeriksaan kadar protein urin pada orang yang mengkonsumsi minuman beralkohol di llingkar timur kota bengkulu menggunakan asam asetat 6% analisis data yang digunakan adalah analisis univariat.Hasil : didapatkan hasil sampel 1 positif (+) 10%, 2 positif (++) 3,33% dan 26 sampel urin negatif (-) 86,67%.Kesimpulan : maka dapat disimpulkan bahwa hampir seluruh responden protein urin negatif (86,67%) dan sebagian kecil positif (+) 10% dan sebagian kecil positif (++) 3,33%.
Comparison of Acidity Degree (pH) on Thrombocyte Concentrate Products: Apheresis Method and Pooling Method
Authors: Ariani Resti , Kuspranoto Abdul H , Aulia Intan
Published: August 2024

One indicator of the decreasing quality of thrombocyte concentrate (TC) during storage is the pH value. Thrombocyte making can use pooling and apheresis methods. The pooling method is carried out by combining 4-6 bags of single thrombocytes with sterile connecting device, while apheresis method is done automatically using apheresis machine.  Quality Control Inspection of TC product is conducted to ensure the quality of the product in accordance with applicable specifications. This study aims to find out the difference in acidity degree value (pH) in thrombocyte concentrate apheresis and pooling methods. This type of research is descriptive comparative with the design of cross sectional section study. The population of research was all the results of pH value examination on thrombocyte apheresis and pooling in UDD PMI Semarang city in 2020, with the number of 48 bags each. The sampling technique used is total sampling. Analysis of research data was conducted univariate and bivariate with the help of SPSS version 25. The average pH value in thrombocyte apheresis 7,145 and in thrombocyte pooling 7,417. Bivariate analysis of thrombocyte apheresis and pooling using Independent Sample T-Test has a significance value of 0.000. From the results of the analysis of research data, there is a significant difference between the pH value in thrombocytes apheresis and pooling method. Because there are differences between the two pH values in thrombocyte products, there needs to be an improvement in the evaluation and monitoring of each product.
IDENTIFIKASI SOIL TRANSMITTED HELMINTS PADA KUBIS DAN LALAPAN DI DALAM PECEL PEDAGANG KAKI LIMA DI KOTA BENGKULU TAHUN 2021
Authors: Sahidan Sahidan , Mustria Mala
Published: August 2024

Latar Belakang : Sayuran merupakan sumber vitamin dan kaya serat bagi tubuh manusia, sayuran sangat penting untuk dikonsumsi bagi kesehatan tubuh. Kebiasaan mengonsumsi sayur berupa lalapan untuk mencampur bahan makanan lain perlu diwaspadai karena proses penanaman yang menggunakan pupuk kandang menyebabkan sayur lebih mudah terjangkit telur cacing. Teknik mencuci sayuran harus benar dengan cara mencuci sayuran di air kran yang mengalir, mencuci lembaran per lembar, kemudian mencelupkan sebentar ke air panas atau membilasnya menggunakan air matang. Selain itu ada faktor lain yaitu dihinggapi lalat atau kecoa sehingga terjadi perpindahan telur cacing dari dalam tubuh ke sayuran. Tujuan penelitian ini adalah untuk mengetahui keberadaan telur cacing Soil Transmitted Helminth pada sayuran kubis dan kemangi pada pedagang pecel lele di Kecamatan Gading Cempaka Kota Bengkulu. Metode: Rancangan penelitian ini adalah survei deskriptif sampel berupa kubis segar dan kemangi pada pedagang pecel lele di Kecamatan Gading Cempaka Kota Bengkulu dengan menggunakan teknik total sampling sebanyak 32 sampel yang terdiri dari 16 sampel kubis dan 16 sampel kemangi. Hasil: Hasil pengamatan mikroskopis hampir separuh (31,25) sampel kubis dan sebagian kecil (12,5) sampel kemangi yang positif terkontaminasi Soil Transmitted Helminth pada sediaan yang telah diperiksa di bawah mikroskop. Kesimpulan: Berdasarkan hasil penelitian terhadap 32 sampel kubis dan kemangi di Kecamatan Gading Cempaka Kota Bengkulu dapat disimpulkan bahwa hampir sebagian (31,25%) sampel kubis terkontaminasi Soil Transmitted Helminth dan sebagian kecil (12,5%). ) sampel kemangi yang terkontaminasi Soil Transmitted Helminth. Saran untuk penelitian selanjutnya dapat dilakukan lebih lanjut mengenai identifikasi Soil Transmitted Helminth pada sayuran kubis dan kemangi pada pedagang pecel lele di Kecamatan Gading Cempaka Kota Bengkulu.
KORELASI KADAR PROTEIN URIN DENGAN UREUM DARAH PADA PASIEN GAGAL GINJAL KRONIK YANG MELAKUKAN HEMODIALISA DI RSHD. HARAPAN DAN DOA KOTA BENGKULU TAHUN 2023
Authors: Cynthia Dewi Devi
Published: August 2024

Pendahuluan: Gagal ginjal kronik (GGK) merupakan suatu sindrom klinis yang disebabkan oleh penurunan fungsi ginjal yang bersifat menahun, bersifat progresif dan cukup lanjut. Apabila penyakit GGK seseorang telah mencapai stadium berat atau terminal maka terapi yang dapat meningkatkan harapan hidup penderita tersebut adalah hemodialisa. Dengan melakukan pemeriksaan protein urin dan ureum secara rutin, pasien akan mengetahui perkembangan fungsi ginjalnya. Sehingga tujuan penelitian ini adalah untuk mengetahui korelasi  kadar protein urin dan ureum darah pada pasien GGK yang melakukan hemodialisa di RSHD Harapan Dan Doa Kota Bengkulu.
Tujuan : Untuk menganalisis apakah ada korelasi kadar protein urin dengan kadar ureum dalam darah pada pasien gagal ginjal kronik yang melakukan hemodialisa.
Metode Penelitian : Peneltian ini menggunakan survei analitik dengan desain penelitian cross sectional. Pengambilan sampel menggunakan teknik purposive sampling. Sampel dalam penelitian ini adalah 56 sampel pasien GGK yang melakukan HD. Penelitian ini dilakukan di Laboratorium RSHD Harapan Dan Doa Kota Bengkulu, pada tanggal 12 Juli sampai 25 Agustus 2023.
Hasil : uji statistik korelasi dan regresi dari 50 pasien GGK yang melakukan HD di RSUD Dr. M. Yunus Bengkulu yaitu korelasi (R =0,958) dan koefisein derterminasi (R2 =0,915) dengan nilai (pvalue =0,000 < 0,005). Yang artinya menunjukkan ada hubungan yang kuat antara kadar ureum darah dengan protein urin pada pasien GGK yang melakukan HD di RSHD Harapan Dan Doa Kota Bengkulu.
Kesimpulan : Terdapat Korelasi yang signifikan antara kadar  protein urin dan ureum darah pada pasien gagal ginjal kronik yang melakukan hemodialisa di RSHD Harapan Dan Doa Kota Bengkulu Tahun 2023. Hal ini ditunjukan dari uji korelasi dan regresi dengan nilai (pvalue = 0,000 < 0,005)
Saran : Pasien yang menderita gagal ginjal kronik yang melakukan HD dapat melakukan pemeriksaan ureum darah dan protein urin secara rutin
Perceptions, views and opinions regarding the use of mnemonics in teaching-learning: An e-mail based survey among Bangladeshi anatomy teachers
Authors: Akhter Najnin , Masum Md Mohiuddin , Bashar Farhana , Shamim Khondker Manzare
Published: August 2024

Background: In anatomy, there are many ‘mnemonics’ available as memory devices. However, how teachers think about different aspects of these devices regarding teaching-learning has not been adequately addressed. This research aimed to determine the perceptions, views, and opinions of Bangladeshi anatomy teachers on the use of mnemonics.
Methods: This descriptive cross-sectional study was conducted by the Department of Anatomy at Bangabandhu Sheikh Mujib Medical University, Dhaka, from 2017 to 2018. The research involved a self administered survey via e-mail using Google Forms among 63 Bangladeshi anatomy teachers with a post-graduation in anatomy and at least five years of teaching experience. Responses were collected through pre-designed multiple-choice questions, allowing for single or multiple selection and open-ended questions to explore their perceptions, views, and opinions on seven aspects of using mnemonics.
Results: Around 83% of teachers agreed that mnemonics would help effectively memorise anatomical information. Most believed that mnemonic techniques such as ‘Acrostic’ and ‘Rhyme’ would be more effective than ‘Acronym’ and ‘Storytelling’. More than 50% felt that Bangla mnemonics would be more effective than English ones. In teaching anatomy, around 85% preferred to explain a topic first and then introduce the mnemonic. Moreover, half suggested that available English mnemonics could be modified into Bangla to better align with students' understanding levels and cultural context.
Conclusions: Most participants indicated ‘Acrostic’ and ‘Rhyme’ were more effective than ‘Acronym’ and ‘Storytelling’. A common view was that modifying English mnemonics to Bangla would yield better results.
Vascular Damage and Repair - Are Small-Diameter Vascular Grafts Still the “Holy Grail” of Tissue Engineering?
Authors: Bačáková L , Chlupáč J , Filová E , Musílková J , Tomšů J , Wu Yu-Chieh , Svobodová L , Pražák Š , Brož A
Published: August 2024

Cardiovascular diseases are the most important cause of morbidity and mortality in the civilized world. Stenosis or occlusion of blood vessels leads not only to events that are directly life-threatening, such as myocardial infarction or stroke, but also to a significant reduction in quality of life, for example in lower limb ischemia as a consequence of metabolic diseases. The first synthetic polymeric vascular replacements were used clinically in the early 1950s. However, they proved to be suitable only for larger-diameter vessels, where the blood flow prevents the attachment of platelets, pro-inflammatory cells and smooth muscle cells on their inner surface, whereas in smaller-diameter grafts (6 mm or less), these phenomena lead to stenosis and failure of the graft. Moreover, these polymeric vascular replacements, like biological grafts (decellularized or devitalized), are cell-free, i.e. there are no reconstructed physiological layers of the blood vessel wall, i.e. an inner layer of endothelial cells to prevent thrombosis, a middle layer of smooth muscle cells to perform the contractile function, and an outer layer to provide innervation and vascularization of the vessel wall. Vascular substitutes with these cellular components can be constructed by tissue engineering methods. However, it has to be admitted that even about 70 years after the first polymeric vascular prostheses were implanted into human patients, there are still no functional small-diameter vascular grafts on the market. The damage to small-diameter blood vessels has to be addressed by endovascular approaches or by autologous vascular substitutes, which leads to some skepticism about the potential of tissue engineering. However, new possibilities of this approach lie in the use of modern technologies such as 3D bioprinting and/or electrospinning in combination with stem cells and pre-vascularization of tissue-engineered vascular grafts. In this endeavor, sex-related differences in the removal of degradable biomaterials by the cells and in the behavior of stem cells and pre-differentiated vascular cells need to be taken into account.
DETERMINAN PERILAKU PENCEGAHAN PENULARAN TUBERKULOSIS PADA PENDERITA TUBERCULOSIS
Authors: Kistimbar Siti , Latumenasse Rony , Fitri Yenti , Lestaluhu Kasman , Wahyurianto Yasin
Published: August 2024

Abstract: Based on the results of the preliminary study conducted, it was found that 20% of patients with tuberculosis had good behavior and as many as 80% of patients had bad behavior in preventing tuberculosis transmission. This shows that one of the factors that can affect the high number of tuberculosis cases in the Wanasari Health Center working area is that there are still many patients who behave badly in preventing tuberculosis transmission. The purpose of the study was to determine the determinants of tuberculosis transmission prevention behavior in patients with tuberculosis. This research is a quantitative research with cross sectional study design. The research was conducted in the working area of Wanasari Health Center, Brebes Regency. The population as well as the sample used in this study were 62 patients with tuberculosis in the working area of Puskesmas Wanasari Brebes Regency. The sample collection technique used total sampling. Data analysis was done univariate and bivariate. The results showed that there was a relationship between family support (p value: 0.013) and Tb prevention behavior. It is recommended that the health center provide counseling to the patient's family so that they can support the patient in the form of informational support and to the patient It is recommended that the patient use a mask when communicating with other people both inside and outside the home.Keywords: Family Support, Prevention, Tuberculosis.
PENGARUH CURRENT RATIO, DEBT TO ASSET RATIO, DAN NET PROFIT MARGIN TERHADAP PERTUMBUHAN LABA PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2017-2021
Authors: Zaelani Rizal
Published: August 2024

Tujuan dari penelitian ini adalah untuk mengetahui bagaimana Current Ratio, Debt to Asset Ratio, dan Net Profit Margin berpengaruh secara parsial dan simultan terhadap pertumbuhan laba perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia (BEI). Studi ini dilakukan selama lima tahun, dari 2017 hingga 2021.
Metode penelitian yang digunakan adalah metode kuantitatif. Sampel
diambil dengan metode sampling purposive. Data yang digunakan adalah data sekunder dari laporan keuangan yang terdiri dari tujuh perusahaan periode 2017-2021. Analisis koefisien berganda, regresi linier berganda, dan uji hipotesis statistik digunakan secara parsial dan simultan.
Hasil penelitian menunjukkan bahwa rasio saat ini secara parsial memengaruhi pertumbuhan laba. Dimana hasil uji hipotesis menunjukkan dari nilai t hitung 2,055 > t tabel 2,039 serta nilai yang signifikan sebesar 0,048 < 0,05 sehingga H1 diterima. Secara parsial rasio hutang terhadap aset tidak memengaruhi Pertumbuhan Laba. Dimana hasil dari uji hipotesis menunjukkan nilai thitung 0,010 < ttabel 2,039 dan nilai signifikan sebesar 0,992 > 0,05 sehingga H2 ditolak. Net Profit Margin secara parsial memengaruhi pertumbuhan laba. Dimana hasil uji hipotesis menunjukkan nilai t hitung 13,793 > ttabel 2,039 dan nilai yang signifikan sebesar 0,000 < 0,05 sehingga H3 diterima. Current Ratio, Debt to Asset Ratio, dan Net Profit Margin mempengaruhi pertumbuhan laba secara bersamaan. Hasil uji hipotesis menunjukkan nilai signifikan sebesar 0,000 < 0,05 dan F hitung 71,034 lebih besar dari F tabel 2,90, sehingga H4 diterima.
Voting Engagement among Adults with Sickle Cell Disease (SCD): Health Matters
Authors: Miller Jessica , Barker Camela S. , Wood Mary , Jones Brianna , Arnold Tierra , Warren Birchie , Beavers Samanta , Cubilete Erika N. , Brooks Raven , Thompson Oneika , Rosales Jazmin , Delts-Robinson Alyssa , Fulcher Serenia , Brooks Montavia M. , Booker Cypress , Haddock Rani , Muhammad Malik , Whitworth Elaine , Bryson William Jeff , Cubilete Wandy Morel , O’Neal Elaine , Kersey Recardo T. , Reives Sarah , Sollers, III John J. , Benner Jasmine , Byrd Goldie S. , Burford Tanisha , Howerton Brenda , Cliette George , Forde-Hawkins Zack , Munroe, Jr. Courtney , Jones Dana , Livingston Jonathan , Sudhakar Shiv , Sollers, IV John , Donahue Grace , Alick Candice , Parker Debra O. , Boorzt-Marx Richard , Edwards Christopher L.
Published: August 2024

The Voting Rights Act of 1965 was established to enforce voting rights guaranteed by the Fourteenth and Fifteenth amendments. Unfortunately, Blacks faced additional barriers when attempting to exercise their right to vote. Moreover, focusing on voting specifically among adults living with Sickle Cell Disease (SCD), we assessed voter participation as a form of advocacy to evaluate if political involvement was related to psychological status. We found that 72% of adults with SCD in our sample routinely voted in government elections. We examined psychological symptoms using the Symptom Checklist -90 (SCL-90-R). Voters consistently presented with better psychological status than nonvoters. Voters reported significantly lower levels of interpersonal sensitivity, anxiety, specific phobia, and psychosis than nonvoters (p<.05). We interpret our findings as a non-characterological and non-volitional explanation for political participation among adults with SCD.
Analysis of Language Errors in The Level of Phonology in The Movie Habibie and Ainun 3
Authors: Bukhari Ahmad Bukhari Nasution , Diva Azzurra Putri Rialni  , Nurul Hijrah  , Safinatul Hasanah Harahap
Published: August 2024

This research aims to analyze phonological errors in the film Habibie and Ainun 3. The research method used in this research is a qualitative descriptive method. The qualitative descriptive method is fact-finding in the form of a systematic description of data and prioritizing the weight of data and research evidence, even though the research does not use calculations. The data collection technique is by watching films and recording the phonological errors spoken by the actors in the film. There are 20 phonological errors in the film Habibie and Ainun 3. These errors are found in the phonology area of ​​changing the pronunciation of phonemes with 11 errors, the area of ​​phoneme changes with 4 errors, the addition of phonemes with 2 errors, and the area of ​​changing diphthong sounds into single phonemes with 3 errors.
 
Keywords: film, Habibie and Ainun, phonology, linguistics
Problems and Strategies for Learning The Indonesian Language in Grade 2 of Yapita Elementary School, Surabaya City
Authors: Farisia Hernik , Maulidiyah Hilda Khilmatul , Ismiyah Kiki Nadhifatul , Maharani Krisnina , Roichatuzzuhriyah
Published: August 2024

Language can be used to communicate and become an identity in a country. Indonesian language learning is important to implement starting from the lower grades of elementary school. Language skills need to be mastered by students, such as listening, viewing, speaking, reading, and writing. Learners are taught to apply Indonesian well. On the other hand, a problem in the learning process often arises, causing learning to be disrupted. These problems can arise from educators or students. This study aims to determine the application of Indonesian language learning in elementary schools. As well as knowing the issues and strategies used to solve these problems. The method used in this research is qualitative. This study's data were collected through interviewing grade 2 teachers at YAPITA Elementary School in Surabaya City, observation, and documentation. This study also looked at classroom lesson planning documents such as teaching modules. This study shows that teachers experience obstacles in preparing teaching modules, learning delays experienced by students, and no good application of the Indonesian language in daily communication. The influence of the environment around children also affects the level of learning success of students. The learning strategy chosen will be adjusted to the learning model in the classroom. Thus, the teacher can identify the material in advance to determine the appropriate learning model.
Desenvolvimento profissional de professores: uma discussão acerca do conceito
Authors: FERREIRA ANDREIA DE ASSIS , Gestoso de Souza Ana Paula
Published: August 2024

Neste artigo propomo-nos a compor um cenário para a discussão sobre desenvolvimento profissional (DP) e buscar compreender o conceito, através de sua historicidade. Tendo como ponto de partida a seguinte questão de investigação: qual conceito de desenvolvimento profissional tem sido adotado na produção acadêmica em educação, no período de 2000 a 2022? Por meio de um levantamento sistemático, mapeamos a produção brasileira sobre desenvolvimento profissional de professores a partir de uma sistematização de teses, dissertações e artigos nacionais indexados nas bases de dados Capes e Biblioteca Nacional de Dissertações e teses. A pesquisa a partir dos indexadores ‘desenvolvimento profissional’ e ‘desenvolvimento profissional docente’ e ‘desenvolvimento profissional de professores’, identificou 194 artigos. No levantamento realizado na plataforma Capes, foram filtradas 83 dissertações e teses que trazem no seu título o indexador. Identificamos na produção científica sobre desenvolvimento profissional docente diversos desafios, em especial, a falta de definição do construto; o uso do conceito formação como sinônimo de DP e o número incipiente de artigos que consideraram a opinião dos docentes diante do seu próprio DP. Em que pese haver excelentes autores que tratam há tempos do tema, apresentamos contribuição para a construção de uma definição para o construto. Contribuindo para a sistematização do tema DP, identificando a existência ou não de lacunas na literatura sobre o assunto, analisando as publicações e a evolução do conceito.
Educação Financeira e Formação Continuada de Professores: produção de atividade a partir da investigação matemática
Authors: Franzoni Patricia , Barcellos Martins Gabrielle Barcellos Martins , Colares da Silveira Douglas , Araujo Sousa Cristiane
Published: August 2024

Este estudo conta com apoio financeiro da Fundação de Amparo à Pesquisa do Estado RS, caracteriza-se como pesquisa qualitativa e propõe-se a investigar como a produção de tarefas de investigação matemática pode contribuir nos processos de ensino e aprendizagem de Educação Financeira na Educação Básica, tendo em vista que o tema está presente na Base Nacional Comum Curricular e precisa ser discutido. Os integrantes da pesquisa são professores de Matemática, dos anos finais do ensino fundamental e médio (rede pública, educação básica) de um município gaúcho. Os dados produzidos a partir das tarefas, questionário online e gravação de áudio e vídeo online foram analisados mediante a análise textual discursiva, surgindo duas categorias: a) formulação de tarefa investigativa, e b) percepções dos professores com relação a atividade e a aprendizagem. Por meio deste estudo, conclui-se que os professores assumiram um papel mais ativo, foram estimulados e motivados, valorizaram o trabalho em grupo, compartilharam dos seus pensamentos e tiveram êxito na elaboração de tarefas investigativas, o que favoreceu o desenvolvimento da autonomia, a criatividade e o desenvolvimento do espírito crítico, fortalecendo os processos de ensino e de aprendizagem, contribuindo na formação continuada dos professores que estão tendo que buscar conhecimento para se sentirem mais seguros e preparados para ensinar Educação Financeira nas escolas. Espera-se que os resultados possam incentivar os participantes da pesquisa a aderirem a métodos inovadores nas aulas de Matemática, tornando-as mais dinâmicas e interativas aos estudantes.
Palavras-chaves: Educação Financeira, Ensino, Aprendizagem, Formação de Professores.
Obstáculos epistemológicos de Bachelard e o ensino de física: compreendendo dificuldades no aprendizado da decomposição de forças no plano inclinado
Authors: Silva Fábio Ramos da , Gusmão Lucimar Donizete , De Freitas Santos Silvio José
Published: August 2024

Este trabalho traz algumas reflexões acerca das contribuições de Bachelard para o ensino de física, sobretudo sobre a fecundidade da ideia de obstáculos epistemológicos e das repercussões da mesma para a compreensão de dificuldades de aprendizagem no ensino de física. A metodologia da pesquisa se baseia em uma discussão teórica pautada em aspectos gerais do pensamento de Bachelard, principalmente nas suas reflexões relacionadas com as problemáticas da educação científica, e na análise de potenciais obstáculos presentes na aprendizagem da decomposição de forças no plano inclinado. Como resultados, apresenta-se uma discussão sobre algumas dificuldades de aprendizagem presentes na literatura relacionadas ao ensino da decomposição de forças no plano inclinado interpretadas por meio da ideia de obstáculo epistemológico, assim como a proposição de um aparato manipulável como sugestão de um recurso didático que pode colaborar para a superação dos obstáculos elencados. Por fim, discute-se a proficuidade da utilização do aparato em situações de ensino, de modo que possa mobilizar o pensamento dos estudantes, ajudando-os a superar possíveis obstáculos de racionalização.
Possibilidades pedagógicas para o ensino inclusivo de botânica: o Jardim Sensorial em foco
Authors: Santos Roberto Abraão Fonseca dos , Reis Ozielma Neponucena dos , Silva Natanael Charles da , Costa Jeferson Miranda , Fonseca Dyana Joy dos Santos
Published: August 2024

No contexto do ensino inclusivo de botânica na educação básica, esta pesquisa objetivou discutir sobre o potencial pedagógico de um Jardim Sensorial existente no Instituto Federal do Pará (IFPA Campus Abaetetuba) como recurso didático para tal fim. A pesquisa de campo com carácter qualitativo e descritivo, ocorreu na “Casa de Vegetação”, espaço que abriga um Jardim Sensorial situado nas dependências do Instituto, e contém plantas com propriedades sensoriais dos grupos de pteridófitas, gimnospermas e, principalmente, de angiospermas. Foram identificadas e caracterizadas as espécies vegetais existentes no Jardim Sensorial e, em seguida, listadas as suas principais propriedades organolépticas. Após revitalização, o jardim apresenta 18 espécies vegetal com potencial sensorial, distribuídas em 17 famílias, com predominância para espécies exóticas que estimulam principalmente a visão, o tato e o olfato, por meio da folha, flor e/ou caule. A pesquisa apresenta a existência de estreitas relações entre as propriedades organolépticas das plantas com os conceitos de botânica (morfologia e fisiologia vegetal) e os sentidos humanos, contribuindo assim, para o prático ensino inclusivo na área da botânica. Com isso, o espaço pode ser utilizado por público interno e externo, caracterizando-se como um ambiente educativo, inclusivo e social.
A escola e o professor: formação e identidade
Authors: Trezzi Clovis
Published: August 2024

A identidade da escola moderna, que se desenvolveu a partir do século XVII, trouxe novas necessidades de formação para os professores. Estes passaram a trabalhar com situações complexas e precisaram se adaptar às diferentes situações que ocorriam na sala de aula. Ao longo dos séculos, muita coisa mudou na escola, mas este aspecto da formação dos professores continua presente. Este artigo discute a realidade da formação continuada dos professores como algo que acontece dentro da escola, especialmente no trabalho coletivo. O objetivo do artigo é discutir como a formação contínua do professor, que acontece dentro da escola, se desenvolve a partir da experiência que nela é realizada. O trabalho assume a posição de que a formação do professor depende, dentre outras coisas, da maneira como a escola organiza as experiências educativas. O papel da escola continua sendo essencialmente formativo, tanto do aluno quanto do professor. Conclui-se que a construção de espaços coletivos, onde os professores possam dialogar e intercambiar dificuldades e experiências é fundamental para que o professor, de quem são exigidas muitas habilidades, desenvolva a sua identidade junto com a escola.
Estresse e impacto na memória e no funcionamento cognitivo: revisão com enfoque na neurociência
Authors: De Sousa Santos Antocléia , E SILVA MARGARETH APARECIDA , ALVES DOS SANTOS CLÁUDIA LILIAN
Published: August 2024

O estresse é uma resposta fisiológica do corpo diante de situações desafiadoras e perigosas, porém em excesso pode refletir de forma negativa no aprendizado. Nesse sentido, este estudo objetivou por meio de uma revisão de literatura investigar como o estresse pode impactar significativamente nos processos cognitivos e tomada de decisões. Nos procedimentos metodológicos, a pesquisa foi conduzida nas bases de dados “Google acadêmico”, “Redalyc” e “Portal de Periódicos da UNIFESP”. Como resultados encontrados, identificou-se a) como o não gerenciamento do estresse adequado pode gerar problemas significativos na estrutura cerebral. Além de b) estratégias para minimizar os efeitos do estresse como atividades físicas regulares que promovem o bem-estar e melhor regulação da memória. Portanto, recomenda-se para futuros estudos, discussões relacionadas à neurociência e o impacto do estresse em diferentes níveis educacionais, traduzindo o resultado dessas investigações em intervenções educativas.
Análise de Tendências sobre Robótica Educacional no Ensino de Ciências
Authors: Alves do Amaral Jefferson Matheus , Soares Silva Ana Carolina , De Albuquerque Couto Janaina
Published: August 2024

Realizamos uma revisão sistemática das publicações em revistas cientificas A1 e A2, como também na Base de Teses e Dissertações da CAPES a fim de identificar as tendências da produção brasileira sobre a robótica educacional no ensino de ciências. A pesquisa tem por objetivo verificar a incidência de trabalhos científicos sobre o tema Robótica Educacional no Ensino de Ciências. Ao longo dos anos sabemos a necessidade da inclusão das tecnologias na sala de aula e assim encontramos trinta e dois dentro da temática. As principais tendências indicaram que a produção brasileira ainda é escassa em material e utiliza os principais referenciais teóricos já consolidados na literatura internacional. Foi encontrado, também, que os trabalhos utilizaram kit de Arduíno em pesquisas com estudantes do ensino superior e o do kit da Lego com estudantes do ensino fundamental e do médio. Além das pesquisas se debruçarem na área do conhecimento das exatas. Como sugestão para futuras pesquisas, apontamos a necessidade de analisar pesquisas em eventos científicos que envolve a robótica educacional.
Optimal control strategies for HIV and COVID-19 co-infection: a cost-effectiveness analysis
Authors: Batu Tesfaneh Debele , Obsu Legesse Lemecha
Published: August 2024

In the face of ongoing challenges posed by the COVID-19 and the persistent threat of human immunodeficiency virus (HIV), the emergence of co-infections such as COVID-19 and HIV has heightened complexities in disease management. This study aims to identify effective control strategies to mitigate COVID-19 and HIV co-infection, which aggravates the existing challenges posed by these two diseases. To achieve this, we formulated a co-infection model that describes the transmission dynamics of COVID-19 and HIV. Under certain circumstances, we established that HIV infection may facilitate COVID-19 transmission, highlighting the need to identify and implement effective interventions to mitigate COVID-19 and HIV co-infection. As a result, we incorporated four time-dependent control strategies in the co-infection model: HIV prevention, HIV treatment, COVID-19 vaccination, and COVID-19 treatment. Numerical simulations were conducted to support and clarify the analytical results and to show how preventative efforts affect the co-infected population. Simulations confirm that applying any of the study's strategies will reduce the number of co-infection cases. However, the implementation of these strategies is constrained by limited resources. Therefore, a comprehensive cost-effectiveness analysis was conducted to identify the most economically viable strategy. The analysis concludes that implementing a combined approach of vaccination and treatment for COVID-19 emerges as the most cost-effective measure for preventing the spread of COVID-19 and HIV. These findings provide crucial guidance for decision-makers in adopting precise preventive strategies, ultimately aiming to reduce mortality rates among HIV patients.
Meritocracy and inequality in the climate debate in Edinburgh, Scotland
Authors: Hunjan Nia , Gay-Antaki Miriam
Published: August 2024

This paper underscores the role that structural barriers play in climate change research in Edinburgh, Scotland. By employing an intersectional gender analysis we stress how unequal power relations underly our understanding of climate change, influence the quality and nature of climate research and responses developed. Using semi-structured and unstructured interviews with women and men working in climate change, we identify the shared experiences of individuals who face gendered barriers in climate science and policy, examine their perception of privilege, and their consequent perceived success in climate change research. Our findings stress the relationship between the concept of meritocracy, the underrepresentation of women and marginalized groups in science, and the reproduction of systematic barriers to contribute to the climate debate. We stress the importance of relationships and networks in supporting and encouraging marginalized voices to succeed in participating in climate change research and science more broadly.
Autonomic dysfunction as a possible cause of sudden cardiac death in swimming sports
Authors: Dostal Jiri , Hybska Tereza , Saganelidze Khatuna , Pudil Radek , Stasek Josef
Published: August 2024

Introduction

Human diving reflex is a well-studied phenomenon. However, very little is known about the possible relationship between augmented diving reflex and autonomic dysfunction.

Methods

We retrospectively studied a group of four swimmers who underwent a diving reflex test as part of the examination due to symptoms related to autonomic dysfunction during swimming. The control group comprised 11 healthy swimmers with no history of these symptoms. A standardized diving reflex test was performed for each athlete in both groups. Hemodynamic profiles, including heart rate, stroke volume, and cardiac output, were recorded.

Results

There were no statistically significant differences between the groups in any of the three parameters measured before the test. However, at the end of the test, each parameter (heart rate, stroke volume, and cardiac output) was significantly lower in the swimmers who presented with clinical symptoms related to autonomic dysfunction than in the control group.

Conclusion

This observation could shed light on autonomic dysfunction as a possible cause of sudden cardiac death in swimming athletes. It also demonstrated that autonomic dysfunction is presented not only by decreased heart rate but also by stroke volume, causing a drop in cardiac output to the level of hemodynamic collapse.
Influence of gender and academic level on the development of digital competencies in university teachers: a multidisciplinary comparative analysis
Authors: Moreira-Choez Jenniffer Sobeida , Lamus de Rodríguez Tibisay Milene , Arias-Iturralde María Cristina , Vega-Intriago Jisson Oswaldo , Mendoza-Fernández Verónica Monserrate , Zambrano-Acosta Jimmy Manuel , Cardenas-Hinojosa Ruben Dario
Published: August 2024

Introduction

In the digital era, the evolving demands of professional fields, especially in higher education, have accentuated the need for advanced digital competencies among faculty members. Digital competencies are now considered essential for effective teaching, necessitating an in-depth understanding of how these skills are distributed across different demographics, including gender and academic level. This study aims to explore the digital competencies of faculty members at the State University of Milagro, focusing on how these competencies vary by gender and academic level.

Methods

This study employed a quantitative approach within the positivist paradigm to assess the digital competencies of 279 faculty members at the State University of Milagro. Data were collected using the Higher Education Digital Competence Assessment Questionnaire, a validated instrument designed to measure various dimensions of digital skills. Descriptive statistical analysis was conducted using SPSS to evaluate the internal consistency of the competencies and to identify correlations among them, as well as to assess the influence of gender and academic level on these competencies.

Results

The analysis revealed significant correlations among the different dimensions of digital competencies, indicating that proficiency in one area often contributes to the development of skills in other areas. The integrative nature of digital technologies within the academic environment was evident, with a high level of internal consistency observed across the competencies assessed. Notably, differences were found based on gender and academic level, suggesting that these demographic factors influence technological exposure and training, with certain groups displaying higher competency levels in specific areas.

Discussion

The findings highlight the importance of promoting integrative educational strategies that consider the diverse backgrounds of faculty members to ensure equitable development of digital competencies. The observed gender and academic level disparities underline the need for targeted interventions that address the specific needs of different faculty groups. By fostering a more balanced development of digital skills, institutions can enhance overall teaching effectiveness and better prepare faculty to meet the demands of modern educational environments. These results contribute to the ongoing discourse on digital competency development in higher education and suggest avenues for further research on how to bridge existing gaps in digital skills among faculty.
Characteristics of children presenting with new onset diabetes and DKA in the COVID-19 pandemic: a national cohort study
Authors: Ponmani Caroline , Roland Damian , Lyttle Mark D. , Barrett Michael , Hulse Tony , Nijman Ruud G.
Published: August 2024

Objectives

The objective of this study was to evaluate the characteristics of children presenting with new onset diabetes and diabetic ketoacidosis (DKA) in the first COVID pandemic year, compared to pre-pandemic evidence and identify the factors associated with DKA at diagnosis.

Design

Retrospective medical record review.

Setting

Forty-nine pediatric Emergency Departments (EDs) across the UK and Ireland.

Patients

All children aged 6 months to 16 years presenting to EDs with new onset diabetes and DKA, during the COVID-19 pandemic (1 March 2020–28 February 2021) and the preceding year (1 March 2019–28 February 2020).

Results

There were increases in children presenting with new onset diabetes in DKA (395–566, 43%) and severe DKA (141–252, 79%) in the first COVID pandemic year, with patient characteristics similar to the pre-pandemic period. Healthcare seeking delay did not appear to be the sole contributing factor to DKA during the COVID pandemic. The median duration of symptoms of 14 days for both children who presented with and without DKA and were similar across both years; those in severe DKA had shorter median duration of 7 days (IQR: 5–21 days).

Conclusions

There were significant increases in children with new onset diabetes presenting with DKA in the first COVID pandemic year. Increased DKA rates and severity despite a constant median symptom duration suggest a multifactorial process. Studies to determine checkpoints for intervention between symptom onset and diagnosis of diabetes are vital to mitigate the high incidence of DKA in new onset diabetes.
Nomogram construction and evaluation for predicting non-remission after a single radioactive iodine therapy for Graves’ hyperthyroidism: a retrospective cohort study
Authors: Yu Feng , Ma Wenhui , Li Xue , Zhang Ruiguo , Kang Fei , Yang Weidong , Wang Renfei , Wang Jing
Published: August 2024

Background

Radioactive iodine (RAI) therapy is a widely used treatment for Graves’ Hyperthyroidism (GH). However, various factors can impact the non-remission rate of GH after single RAI therapy. This study aimed to develop an online dynamic nomogram to assist physicians in providing personalized therapy for GH.

Methods

Data from 454 GH patients who received RAI therapy were retrospectively reviewed and included in the present study. The univariate and multivariate analysis were conducted to investigate and identify independent influencing factors. The nomogram was developed based on the training cohort to explore non-remission rates. Finally, the reliability and accuracy of the constructed nomogram model were verified in the validation cohort via the calibration, receiver operating characteristic (ROC) curve, and decision curve analysis (DCA).

Results

24-hours radioactive iodine uptake (RAIU24h), effective half-life (Teff), total iodine dose (TID) and iodine dose per gram of thyroid tissue (IDPG) were independent predictors. The nomogram had a high C-index 0.922 (95% CI: 0.892–0.953), for predicting non-remission. The calibration curves demonstrated excellent consistency between the predicted and the actual probability of non-remission. ROC analysis showed that the AUC of the nomogram model and the four independent factors in the training cohort were 0.922, 0.673, 0.760, 0.761, and 0.786, respectively. The optimal cutoff value for the total nomogram scores was determined to be 155. A total score of ≥155 indicates a higher likelihood of non-remission after a single RAI therapy for GH, whereas a score below 155 suggests a greater likelihood of remission. Additionally, the DCA curve indicated that this nomogram had good clinical utility in predicting non-remission.

Conclusion

An online nomogram was constructed with good predictive performance, which can be used as a practical approach to predict and assist physicians in making personalized therapy decisions for GH patients.
Effectiveness of various interventions for non-traumatic osteonecrosis: a pairwise and network meta-analysis
Authors: Zhai Shaoyang , Wu Rui , Zhao Jie , Huang Wang , Hu Weiwei , Huang Weichen
Published: August 2024

Background

Osteonecrosis of the femoral head (ONFH) is acknowledged as a prevalent, challenging orthopedic condition for patients.

Purpose

This study aimed to evaluate the efficacy of various interventions for non-traumatic ONFH and provide guidance for clinical decision-makers.

Methods

We searched PubMed, Embase, Cochrane Library, and Web of Science databases from inception to February 2023 for relevant randomized controlled trials evaluating treatments for femoral head necrosis, without language restrictions. Quality evaluation was performed using the Cochrane risk-of-bias assessment tool, and analysis was performed using Stata 15.1.

Results

Eleven randomized controlled trials were included in this study. The meta-analysis results revealed that CellTherapy [MD= -3.46, 95%CI= (-5.06, -1.85)], InjectableMed [MD= -3.68, 95%CI= (-6.11, -1.21)], ESWT [MD= -2.84, 95%CI= (-4.23, -1.45)], ESWT+InjectableMed [MD= -3.86, 95%CI= (-6.22, -1.53)] were significantly more effective in improving VAS pain score than CD+PTRI, as well as CD+BG+CellTherapy, and CD+BG. Furthermore, CD+BG+CellTherapy was better than CD+BG [MD= -0.97, 95%CI= (-1.71, -0.19)]. The SUCRA ranking for HHS score indicated that CellTherapy (77%) has the best effectiveness rate, followed by ESWT+InjectableMed (72.2%), ESWT (58.3%), InjectableMed (50%), CD+PTRI (31.4%), and CD+BG (11%). In terms of WOMAC and Lequesne scores, the meta-analysis showed no statistically significant differences between the experimental group CD+BG+CellTherapy and the control group CD+BG.

Conclusion

CellTherapy and non-surgical ESWT combined with medication or CellTherapy have the best effect on ONFH. Surgical CD+BG combined with CellTherapy is more effective than CD+BG alone. ESWT+InjectableMed is recommended for short-term or acute onset patients, while ESWT is recommended for long-term patients.

Systematic review registration

https://www.crd.york.ac.uk/PROSPERO, identifier CRD42024540122.
Application of flow and heat transfer network analysis method to the core of a prismatic gas-cooled micro reactor
Authors: Shuoting Zhang , Jianhua Dong , Zhe Zhou , Zheng Huang , Guoming Liu , Qiaoyan Chen
Published: August 2024

The prismatic gas-cooled micro reactor core is composed of graphite prismatic blocks with gaps between them. The coolant passes through the gap to form flows that affect the flow and temperature distribution of the core. Conventionally, computational fluid dynamics methods have been used for prismatic gas-cooled reactor core analysis. However, they require considerable computational time and cost. For rapid and accurate calculation, in this study, a flow and heat transfer network analysis method is developed for evaluation of the core flow and temperature distribution. Finally, the calculated results of the flow heat transfer network analysis method are compared with the calculated results of computational fluid dynamics. The results show that the results of the flow heat transfer network analysis method are in good agreement with the results of computational fluid dynamics.
Genetic insights and emerging therapeutics in diabetic retinopathy: from molecular pathways to personalized medicine
Authors: Pei Xiaoting , Huang Duliurui , Li Zhijie
Published: August 2024

Diabetic retinopathy (DR) is a major complication of diabetes worldwide, significantly causing vision loss and blindness in working-age adults, and imposing a substantial socioeconomic burden globally. This review examines the crucial role of genetic factors in the development of DR and highlights the shift toward personalized treatment approaches. Advances in genetic research have identified specific genes and variations involved in angiogenesis, inflammation, and oxidative stress that increase DR susceptibility. Understanding these genetic markers enables early identification of at-risk individuals and the creation of personalized treatment plans. Incorporating these genetic insights, healthcare providers can develop early intervention strategies and tailored treatment plans to improve patient outcomes and minimize side effects. This review emphasizes the transformative potential of integrating genetic information into clinical practice, marking a paradigm shift in DR management and advancing toward a more personalized and effective healthcare model.
Natural killer cells: a future star for immunotherapy of head and neck squamous cell carcinoma
Authors: Dong Shuyan , Zhao Ming , Zhu Jin , Li Ting , Yan Mingze , Xing Kaixun , Liu Peng , Yu Shan , Ma Jian , He Hongjiang
Published: August 2024

The interplay between immune components and the epithelium plays a crucial role in the development and progression of head and neck squamous cell carcinoma (HNSCC). Natural killer (NK) cells, one of the main tumor-killing immune cell populations, have received increasing attention in HNSCC immunotherapy. In this review, we explore the mechanism underlying the interplay between NK cells and HNSCC. A series of immune evasion strategies utilized by cancer cells restrict HNSCC infiltration of NK cells. Overcoming these limitations can fully exploit the antineoplastic potential of NK cells. We also investigated the tumor-killing efficacy of NK cell-based immunotherapies, immunotherapeutic strategies, and new results from clinical trials. Notably, cetuximab, the most essential component of NK cell-based immunotherapy, inhibits the epidermal growth factor receptor (EGFR) signaling pathway and activates the immune system in conjunction with NK cells, inducing innate effector functions and improving patient prognosis. In addition, we compiled information on other areas for the improvement of patient prognosis using anti-EGFR receptor-based monoclonal antibody drugs and the underlying mechanisms and prognoses of new immunotherapeutic strategies for the treatment of HNSCC.