bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Kemampuan Pemecahan Masalah Matematis Ditinjau dari Self Efficacy Siswa
Authors: Aprilia Resa , Destiniar Destiniar , Septiati Ety
Published: May 2023

Penelitian ini bertujuan untuk mendeskripsikan bagaimana kemampuan pemecahan masalah matematis siswa SMP Negeri 5 Muara Enim ditinjau dari self-efficacy siswa pada materi aritmatika sosial. Metode yang digunakan dalam penelitian ini adalah deskriptif kuantitatif. Sampel penelitian ini yaitu siswa kelas VII SMP Negeri 5 Muara Enim yang berjumlah 24 siswa. Teknik pengumpulan data dalam penelitian ini adalah tes kemampuan pemecahan masalah matematis dan angket self-efficacy siswa. Teknik analisis data menggunakan deskriptif kuantitatif. Hasil dari penelitian ini menunjukkan bahwa; 1) self-efficacy siswa terdiri dari self-efficacy tinggi (9 siswa), sedang (6 siswa), rendah (9 siswa); 2) keterampilan mengatasi masalah di kelas tinggi (5 siswa), sedang (11 siswa), rendah (8 siswa); 3) siswa yang memiliki self-efficacy tinggi dengan kemampuan pemecahan masalah tinggi dapat memenuhi keempat indikator kemampuan pemecahan masalah, siswa self-efficacy sedang dengan kemampuan pemecahan masalah sedang kurang mampu memenuhi keempat indikator kemampuan pemecahan masalah serta siswa yang memiliki self-efficacy rendah dengan kemampuan pemecahan masalah rendah tidak mampu memenuhi indikator pemecahan masalah. Jadi dapat disimpulkan bahwa semakin baik self-efficacy siswa maka semakin mudah untuk menyelesaikan masalah dan semakin rendah self-efficacy siswa, semakin sulit untuk mengatasi masalah
Persepsi Siswa Terhadap Metode Mengajar Guru Matematika Pada Era New Normal
Authors: Aslina Rahmil , Imamuddin M. , Isnaniah Isnaniah , Rahmi Ulva
Published: May 2023

Penelitian ini bertujuan untuk mengetahui bagaimana persepsi siswa MTs S Muhammadiyah Alamanda, Kabupaten Pasaman Barat mengenai metode mengajar guru pada era new normal. Jenis penelitian ini merupakan penelitian pendekatan kuantitatif dengan metode survei. Sampel penelitian adalah 55 orang siswa kelas VII MTs S Muhammadiyah Alamanda Kabupaten Pasaman Barat Provinsi Sumatera Barat. Data yang dikumpulkan menggunakan angket dianalisis secara deskriptif. Hasil penelitian menyimpulkan bahwa pembelajaran di MTs S Muhammadiyah Alamanda di era new normal dilakukan secara tatap muka terbatas di dalam kelas (dibagi berdasarkan sift dan waktu belajar dikurangi) dan daring. Menurut siswa, guru sudah mampu mengelola kelas dengan baik, baik secara daring maupun di dalam kelas. Siswa cukup dilibatkan dalam pembelajaran, dan guru memberikan umpan balik berupa pujian. Siswa berpendapat bahwa pembelajaran yang dilaksanakan dapat mendukung tercapainya tujuan belajar dan lebih dari 50% mampu memahami materi yang disampaikan guru. Waktu belajar di dalam kelas yang terbatas cukup menyulitkan siswa, namun guru mampu mensiasatinya dengan menggunakan lembar kerja siswa dan tugas yang dikumpulkan secara daring. Hasil penelitian ini menunjukkan bahwa pembelajara di era new normal ini dapat dilakukan dengan baik, dengan catatan guru harus mampu merancang dan mendesain pembelajan inovatif dan variatif secara sistematis, serta disesuaikan dengan kebutuhan siswa dan tetap menyenangkan walaupun dilakukan secara daring.
Гипотеза Кшижа и одно дифференциальное уравнение
Authors: Ступин Денис
Published: May 2023

Найдена точная оценка модулей тейлоровских коэффициентов на классах функций, ограниченных снизу по модулю.
ANALISIS KEBIJAKAN PENGAWASAN PROGRAM DAN KEGIATAN KEPOLISIAN DI POLRES SORONG SELATAN
Authors: Siregar Hary Yudha , Akim Akim , Djuyandi Yusa
Published: May 2023

Tujuan dari penelitian ini adalah untuk melakukan analisis terhadap pengawasan program dan kegiatan kepolisian pada Polres Sorong Selatan. Jenis penelitian ini adalah kualitatif dengan menggunakan studi kepustakaan, observasi dan wawancara sebagai metode untuk mengumpulkan data baik primer maupun sekunder. Hasil dari penelitian ini menunjukkan bahwa pengawasan program dan kegiatan kepolisian pada Polres Sorong selatan belum diterapkan secara optimal dengan implikasi rendahnya pencapaian target kinerja. Hal ini disebabkan oleh beberapa kelemahan pada bidang sumber daya manusia, sarana prasarana, anggaran dan metode yang digunakan. Oleh karena itu, perlu untuk dilakukan sosialisasi untuk meningkatkan pemahaman terhadap tugas pokok dari fungsi pengawasan, meningkatkan kemampuan para petugas dan perlu untuk dilakukan pelatihan bersama antar fungsi sehingga terjalin koordinasi yang baik antar satuan kerja pada Polres Sorong Selatan. The objectives of this study is to analyze the policy of monitoring police programs and activities at the Polres Sorong Selatan. This is a descriptive qualitative research by using library study, observation and interviews were used to collect the primary also secondary data. The results of this study showed that the monitoring of policy implementation on programs and activities at Polres Sorong Selatan has not been optimally implemeted with the implication that the achievement performance and accountability is still low. This is due to constraints in the field of personnel, infrastructure, budget and methods used. Therefore, i tis necessary to conduct socialization to provide understanding of the main tasks of the supervisory function, improve the ability of officers and carry out joint training with related functions so that there is a good relationship between works units in Polres Sorong Selatan.
ANALISIS KEPUASAN MASYARAKAT MENGENAI PELAYANAN PARKIR PADA PUSKESMAS DI JAKARTA UTARA
Authors: Rustanto Agung Edi , Caniago Aspizain
Published: May 2023

Penelitian ini terkait dengan kepuasan masyarakat mengenai pelayanan parkir alternatif yang ada di sekitar puskesmas di Jakarta Utara. Populasi dari penelitian ini jumlahnya tidak diketahui secara pasti karena sangat banyak jumlah pengunjung atau pasien puskesmas yang datang ke puskemas tanpa diketahui jumlahnya secara pasti. Dengan demikian sampel dihitung dengan rumus lemeshow, yang hasilnya yaitu sebanyak minimal 96 responden. Jenis penelitian yang digunakan adalah penelitian kuantitatif, dengan teknik pengumpulan data menggunakan kusioner dan ditambah dengan menggunakan hasil wawancara. Teknik analisis data yang digunakan adalah menggunakan teknik regresi sederhana.. Hasil penelitian menunjukkan bahwa seluruh hipotesis telah di terima karena hasil uji hipotesis yaitu positif dan signifikan. Dari hasil Uji Parsial atau Uji-t didapat bahwa nilai koefisien regresi atau t-tabel adalah sebesar 9.275 yang artinya lebih besar dari t-hitung yaitu 1,660 dengan demikiran dapat disebut bahwa ada pengaruh yang signifikan pelayanan parkir terhadap kepuasan masyarakat, dan didukung nilai signifikansinya yaitu 0,000 < 0,05, maka Ho ditolak dan Ha diterima. Hasil koefisien determinasi pada penelitian ini yaitu sebesar 0.439. Ini berarti bahwa pelayanan parkir berpengaruh positif dan signifikan terhadap kepuasan masyarakat sebesar 43,9%. This research is related to community satisfaction regarding alternative parking services around the puskesmas in North Jakarta. The population of this study is not known with certainty because there is a very large number of puskesmas visitors or patients who come to the puskesmas without knowing the exact number. Thus the sample is calculated using the Lemeshow formula, the result of which is a minimum of 96 respondents. The type of research used is quantitative research, with data collection techniques using questionnaires and coupled with the results of interviews. The data analysis technique used is using a simple regression technique. The results showed that all hypotheses had been accepted because the results of the hypothesis testing were positive and significant. From the results of the Partial Test or t-test, it is found that the value of the regression coefficient or t-table is 9,275, which means that it is greater than the t-count, namely 1,660, so it can be said that there is a significant effect of parking services on community satisfaction, and it is supported by its significance value, namely 0.000 <0.05, then Ho is rejected and Ha is accepted. The result of the coefficient of determination in this study is equal to 0.439. This means that parking services have a positive and significant effect on community satisfaction by 43.9%.
ANALYSIS OF PB CONTENT IN LEAVES OF COVERING PLANTS IN VARIOUS ROADS IN PALEMBANG CITY
Authors: Hasdevi Hasdevi , Suheryanto Suheryanto , Susilawati Susilawati
Published: May 2023

Alternative Decree of the Director General of Oil and Gas No. 3674K/24/DJM/2006 dated March 17, 2006 concerning Standards and Quality (Specifications) of Gasoline-Type Fuel Oil Marketed Domestically where in the attachment to the Specification for Gasoline-Type Fuel Oil RON 91 and RON 95 (Pertamax) still contains Pb of 0.013 grams per liter. The exhaust gas produced by motorized vehicles using leaded fuel emits Pb into the environment and has the potential to be absorbed into the leaf tissue of road shade plants. The aim of this study was to examine the Pb content in the leaves and determine the effect of the Pb content in the ambient air on the Pb content in the leaves of various cover crops on Jalan Raya Palembang City. The research samples were leaves of mahogany, umbrella tree, burmese rosewood, bullet wood tree, and rain tree which were dominant and had similarities on Jl. Soekarno Hatta – Alamsyah Ratu Prawiranegara, Jl. Cabbage. H. Burlian, Jl. Jend. Sudirman, Jl. Jend. Basuki Rahmad, Jl. Jend. R. Soekanto, Jl. Jend. Ahmad Yani. Jl. governor HA. Bastari. Analysis of the Pb content in leaves and air using the AAS (Atomic Absorption Spectrophotometer) method. The results of the study found that the highest Pb content in the leaves of the Mahogany plant was on Jl. Jend. Basuki Rahmad 0.112 mg/kg while the lowest was on Jl. governor HA. Bastari <0.081 mg/kg. Pb content in umbrella tree plants in all roads < 0.081 mg/kg. The highest Pb content in burmese rosewood plants is on Jl. Jend. Basuki Rahmad 0.116 mg/kg while the lowest was on Jl. governor HA. Bastari <0.081 mg/kg. The highest Pb content in bullet wood tree Jl. Jend. Basuki Rahmad 0.099 mg/kg while the lowest is on Jl. governor HA. Bastari <0.081 mg/kg. The highest Pb content in rain tree is on Jl. Jend. Basuki Rahmad 0.089 mg/kg while the lowest is on Jl. governor HA. Bastari <0.081 mg/kg. The highest Pb content in ambient air is on Jl. Jend. Basuki Rahmad 0.06 ʯg/Nm3 while the lowest is on Jl. Jend. R. Soekarno. The Pb content in the ambient air affects the Pb content in the leaves.
Two new species of the genus Agistemus Summers (Acari: Stigmaeidae) from Saudi Arabia
Authors: Kamran Muhammad , Mirza Jawwad Hassan , Elgoni Nasreldeen Ahmed , Alatawi Fahad Jaber
Published: May 2023

Two new predatory mites of the genus Agistemus Summers (Acari: Prostigmata: Stigmaeidae) namely A. neocollyerae n. sp. and A. arabensis n. sp. are described and illustrated based on adult females. Additionally, two species namely A. simplex González-Rodriguez and A. floridanus González-Rodriguez are reported as new records for the stigmaeid mite fauna of Saudi Arabia. A regional key to reported species of the genus Agistemus is also provided.
Calculation of the discount rate for the Russian market in present-day conditions
Authors: VORONOV Dmitrii S. , RAMENSKAYA Lyudmila A. , DOLZHENKO Ruslan A.
Published: May 2023

Subject. This article focuses on the consideration of the algorithm and methodological approaches to assessing the cost of capital.
Objectives. The article aims to develop a practical algorithm for assessing the cost of capital and calculating the discount rate based on ruble risk-free assets and Russian financial statistics.
Methods. For the study, we used the Weighted Average Capital Cost (WACC) and Capital Asset Pricing (CAPM) models.
Results. The article offers a tested step-by-step algorithm for calculating the cost of capital and risk premium loading to it using domestic financial statistics. It also justifies the need to take non-systematic risks out and beyond the weighted average capital cost and offers a deterministic mechanism for their assessment.
Conclusions and Relevance. The author-developed algorithm for estimating the cost of capital, as well as methodological recommendations for its use, can be used by domestic investors to make the necessary decisions, as well as by the financial services of Russian companies to build the economic policy of the company. Using the proposed approach may help obtain a more adequate assessment of the cost of capital of Russian companies for domestic investors, thereby improving their competitiveness.
مستقبل النظام السياسي في دولة جنوب السودان
Authors: م.د. محمد شطب عيدان
Published: May 2023

يمرُّ النظام السياسي في دولة جنوب السودان الفتية التي تأسست عام 2011 بمتغيرات تنحت في واقع الدولة عموماً وبالمؤسسات السياسية المشكّلة لهذا النظام خصوصاً، وتتضمن هذه المتغيرات تحديات معرقلة وعوامل دعم لاستمراره تتوزع في بيئتي النظام الداخلية والخارجية، وتمثّل البوصلة التي يمكن من خلالها معرفة اتجاهات مستقبل هذا النظام وفقاً لآلية تعامله معها بتقليل الآثار السلبية للتحديات واستغلاله للفرص المتاحة في عوامل الدعم.

وبنظرة عامّة إلى الشأن الجاري يمكن القول أن ابرز المشكلات التي تواجه دولة جنوب السودان هي تحديات داخلية منها تحسين وضع البنية الأساسية المتردية للاقتصاد واستكمال بناء مؤسسات الدولة، والصراعات القبلية، والنزاعات من أجل الوصول إلى الماء والمراعي والماشية، وهيمنة قبيلة الدينكا على الحكم، والفساد وانعدام الشفافية والمحاسبة، وانتشار الأمراض والأوبئة ومشكلة توطين الجنوبيين القادمين من الخارج إلى الدولة وغيرها من المشكلات، إضافة إلى التحديات في إقليم الدولة التي تأخذ فيه العلاقة مع دولة السودان الحصة الأكبر منه، إضافة إلى المشكلات الحدودية مع الدول المجاورة ومواجهة الحركات المسلحة كجيش الرب وغيرها.
A rare form of leishmaniasis, identified in the Russian Federation
Authors: Artamonova Olga G. , Monchakovskaya Ekaterina S. , Kubanov Alexey A. , Rakhmatulina Margarita R. , Kuznetsov Oleg E. , Synkova Darya A. , Verbenko Dmitry A.
Published: May 2023

Diffuse cutaneous leishmaniasis is a rare form of cutaneous leishmaniasis characterized by an inadequate immune response of the host cells to parasitic invasion (weak T-helper (Th)1 response or Th2 response with the production of interleukin IL-4 and IL-10). The characteristic features of the disease include diffuse nodular eruption, masquerading as leprosy and a frequent association with immunosuppression (HIV co-infection, for example). The Russian Federation is a non-endemic country for leishmaniasis, but this disease can be brought into the country by tourists, immigrants, refugees and military personnel. A clinical case of diffuse cutaneous leishmaniasis and HIV co-infection is presented. The patient was a citizen of Uzbekistan, a country endemic for leishmaniasis. The authors were unable to find domestic scientific publications describing cases of diffuse cutaneous leishmaniasis detected in the Russian Federation. The presented clinical case of diffuse cutaneous leishmaniasis in a patient with HIV is the first in the Russian literature.
Parietal and occipital hair loss patterns in initial stages of androgenic alopecia in men
Authors: Kondrakhina Irina N. , Verbenko Dmitry A. , Zatevalov Alexander M. , Deryabin Dmitry G.
Published: May 2023

Background. The initial stages of androgenetic alopecia in men are characterized by a variety of clinical manifestation in the parietal or occipital scalp regions. However, the differences in the pathogenesis of hair loss patterns are not well understood, selective treatment has not been developed.
Aims. Trichological characteristics of patients with initial stages of androgenetic alopecia with identification of genetic and non-genetic factors that determine the hair loss in the different scalp regions, and their response to conservative therapy.
Materials and methods: Trichograms were photodocumented using an AramoSG microcamera (Republic of Korea). The genetic factor was analyzed by mini-sequencing of single nucleotide polymorphisms rs929626, rs5919324, rs1998076, rs12565727, rs756853. The non-genetic factors study included hormonal status (total and free testosterone, dihydrotestosterone, 17OH-progesterone, dehydroepiandrostenone, SHBG) and blood content of trace elements (Mg, Ca, Zn, Cu, Se, Fe) and vitamins (B12, D, E, folic acid). Conservative treatment was topical application of a minoxidil 5% (twice-a-day, 4 months) and a micronutrient deficiencies personalized correction.
Results. The study included 47 man with initial stages of androgenetic alopecia. Their trichological examination showed two patterns, consisting a predominant decrease in the hair density and diameter in the parietal and occipital scalp regions, which were subgroups formation criteria. An intergroup comparison revealed similar genetic risk, while hormonal parameters (increased dihydrotestosterone levels, a decrease in free testosterone) characterized the subgroup with parietal hair loss pattern. Also, a multiple deficiency of Zn, Cu, Se and vitamins B12, D, folic acid was detected in all patients. Subsequent conservative treatment had a positive effect in patients with parietal hair loss pattern, while in patients with occipital pattern no significant response was observed.
Conclusions. The study develops ideas about differences between androgen-dependent parietal and androgen-independent occipital hair loss patterns in the initial stages of androgenetic alopecia, which requires different approaches to their conservative therapy.
The role of the aromatic hydrocarbon receptor in the pathogenesis of atopic dermatitis
Authors: Gorodnichev Pavel V.
Published: May 2023

The aromatic hydrocarbon receptor (AhR) is a cytoplasmic receptor and transcription factor that regulates a wide range of biological and toxicological effects by binding to specific ligands. Among the effects there is detoxification of xenobiotics, maintenance of tissue homeostasis, regulation of the immune response. The structure and functions of AhR are described in the review. The mechanisms of skin homeostasis with the participation of the aromatic hydrocarbon receptor such as the effect on oxidative reactions and participation in maintaining the barrier function of the epidermis are demonstrated in details. The role of AhR in the pathogenesis of atopic dermatitis is discussed. The participation of AhR in the implementation of immune mechanisms of this disease as well as in the regulation of the production of key proteins of the skin barrier is shown. The data on the therapeutic value of its pharmacological modulation including the results of clinical studies of the topical ligand AhR Tapinarof are presented. The role of the aromatic hydrocarbon receptor in the realization of the effect of phototherapy of atopic dermatitis is demonstrated.
Ateroszklerotikus és egyéb artériás szövődmények daganatos megbetegedésekben
Authors: Süveges Péter , Boussoussou Nora , Sármán Balázs
Published: May 2023

A 21. századot antropogenikus korként lehet meghatározni, amelyben az ipari forradalom gazdasági fellendülést okozó hatása mellett a súlyos krónikus betegségek előfordulási aránya is növekedett (környezeti és egészségügyi károsító tényezők miatt). Korunk legelterjedtebb népegészségügyi terhei közé tartozó, világszerte vezető mortalitási tényezőnek számító krónikus betegségcsoportba tartoznak a daganatos elváltozások, az ateroszklerózis, és az artériás megbetegedések. Az egyre hatékonyabb kezelési lehetőségeknek köszönhetően a daganatos betegségek túlélési rátája mindinkább javul, jelenleg megközelítően 12 millió daganatos betegséget túlélő egyén él Európában. Mindemellett évente, világszerte közel 17,9 millió a szív- és érrendszeri betegségek mortalitási rátája. A jövőben egyre több olyan betegre számíthatunk, akiket mind a két betegségtípus érint. Tekintettel arra, hogy mindkét betegség kialakulása multifaktoriális okokra vezethető vissza, számos megegyező molekuláris kialakulási útvonal, patomechanikus tényező, illetve etiológiai faktor játszik szerepet a kórképek előfordulásában. A daganatos betegségek direkt úton, illetve a radio és/vagy kemoterápián keresztül indirekt úton is rendelkeznek ateroszklerózis és artériás megbetegedést okozó hatásokkal. Összefoglaló cikkünkben a daganatos megbetegedések ateroszklerotikus és artériás elváltozásokkal való összefüggését mutatjuk be.
Amit a kardiológus nem lát: a kardiotoxikus gyógyszerek daganatellenes hatásai
Authors: Rubovszky Gábor , Kocsis Judit , Torday László , Bittner Nóra
Published: May 2023

A daganatellenes gyógyszeres kezeléseknek vannak rövid és hosszú távon jelentkező mellékhatásai. Az antraciklinterápia és a szívelégtelenség közötti összefüggés rávilágított arra, hogy a mellékhatások lehetnek kardiális vagy tágabban kardiovaszkuláris (CV) jellegűek. A későbbiekben számos más onkológiai készítményről is kiderült, hogy vezethetnek CV-szövődményhez, amik egyrészt a daganatellenes kezelés sikerességét rontják, valamint szükségessé teszik kardiológusokkal való szoros együttműködést és a kardiológusok tájékozottságát ezen a téren. A kardiológusok elsősorban az onkológiai kezelések CV-mellékhatásait ismerik, valamint a szükséges diagnosztikus és terápiás lehe- tőségeket ezen mellékhatások elhárításához. Ugyanakkor kevesebb információjuk van az egyes kezelések daganatetlenes hatásáról, hogy mi a jelentősége az egyébként sok esetben igen toxikus kezeléseknek. A célunk az volt, hogy a rendelkezésre álló keretek között felmutassuk néhány fontos jellemzőjét ezeknek a kezeléseknek. A téma nagysága az adott keretek között nem teszi lehetővé, hogy átfogó képet nyújtsunk, de a szerzők az egyes készítményeknél eltérő szempontokat is figyelembe véve igyekeztek az onkológiai kezelések és az azokat érintő megközelítés sokszínűségét érzékeltetni. A legújabb európai ajánlás alapján azokat a gyógyszercsoportokat vettük sorra, amiknél ismerten előfordul CV-mellékhatás.
Primer prevenció, kardiovaszkuláris rizikó optimalizáció daganatos betegekben: az életmód és a gyógyszeres terápia szerepe
Authors: Juhász Ágnes , Hajdú Anett , Dank Magdolna
Published: May 2023

A daganatellenes kezelések kardiovaszkuláris toxicitása kiemelt figyelmet igényel az onkológusok és a kardiológusok körében, ami egy új interdiszciplináris megközelítéshez vezetett a kardio-onkológia területén. Egyre több bizonyíték rámutat arra, hogy egyértelmű az összefüggés a kockázati tényezők és a kardiovaszkuláris, valamint a daganatos megbetegedések között. A dohányzás, az elhízás, a helytelen táplálkozás és az inaktív életmód mind növelik a szív- és érrendszeri és a daganatos betegségek kialakulását, amelyek ugyanakkor kedvezőtlenül befolyásolják az onkológiai kezelések kimenetelét is, ezáltal a korai mortalitás is emelkedni fog. A közös kockázati tényezők ismerete fontos a megelőzés szempontjából és ezek eliminálásával, az életmód mielőbbi megváltoztatásával hatékonyabb támogatást tud nyújtani a kezelések során, aminek következtében a halálozás lecsökken és a betegek életminősége is pozitív tendenciát mutat.
A krónikus koronáriaszindróma optimális kezelése: kombinációs lehetőségek
Authors: Nemes Attila
Published: May 2023

Bár a krónikus koronáriaszindróma kezelése szakmai irányelvek által meghatározott elvek szerint kezelendő, érdemes átgondolni bizonyos antianginás kezelések fontosságát. A hemodinamikai és metabolikus antianginás gyógyszeres kezelés minél koraibb kombinációban történő használata segíthet betegeink anginás panaszainak csökkentésében, életminőségük és terápiahűségük javításában. A jelen összefoglaló ezekre a tényekre kívánja felhívni a figyelmet.
Az immunellenőrzőpont-gátló onkológiai terápiák kardiovaszkuláris mellékhatásai
Authors: Drobni Zsófia Dóra , Varga V. Zoltán , Pozsonyi Zoltán , Szűcs Andrea , Becker Dávid , Vágó Hajnalka , Merkely Béla
Published: May 2023

Az elmúlt 30 évben jelentős előrelépés történt a daganatellenes terápiákban. Az immunterápiák bevezetése számottevően javította az onkológiai betegek túlélését. Az immunellenőrzőpont-gátlók (ICI) az immunterápiáknak leggyakrabban alkalmazott típusát képviselik. A daganatos betegek emelkedett kardiovaszkuláris rizikóval rendelkeznek nem csupán a közös rizikófaktorok miatt, hanem bizonyos daganatellenes terápiák is jelentős kardiovaszkuláris mellékhatással járhatnak. A kardiovaszkuláris megbetegedések patomechanizmusában a gyulladás és az immunrendszer meghatározó szerepe jól ismert. Ezek alapján felmerül, hogy az ICI-terápiában részesülő daganatos betegek fokozott kardiovaszkuláris kockázattal rendelkezhetnek. Az alábbiakban rövid áttekintést adunk az ICI-terápia kardiotoxicitásának előfordulásáról, diagnózisáról, kezeléséről és szűréséről. Ezen túl ismertetjük az idén nyáron publikált Európai Kardiológus Társaság témába illő ajánlásait is.
Molten Salt Synthesis of Multi-Faceted Pure-Phase Spinel LiNi0.5Mn1.5O4 Platelets
Authors: Oney Gozde , Olchowka Jacob , Demortières Arnaud , Weill François , Croguennec Laurence
Published: May 2023

The spinel LiNi0.5Mn1.5O4 is largely studied as a positive electrode material for lithium-ion batteries, but further optimization of its properties are required to enable its commercialization. The superior electrochemical performance of the disordered polymorph of LiNi0.5Mn1.5O4 is limited by its traditional method of synthesis. This solid-state route generates impurities that reduce specific capacity and results in the formation of octahedral particles with exposed {111} facets, thus limiting explo-ration of the effects of surface orientation. In this work, we report for the first time the preparation of a disordered impurity-free LiNi0.5Mn1.5O4 with platelet-like morphology via molten salt synthesis. We discovered that these platelets exhibit multi-ple surface orientations, including {111}, {112} and six other high-indexed facets, and deliver equivalent energy storage performance to their octahedral counterpart. Such ability to tune primary particle morphology and orientation will open the gate to investigate mechanisms at the individual particle level using spectroscopy and microscopy techniques.
Quantum Dynamics of Oblique Vibrational States in the Hénon-Heiles System
Authors: Zuniga Jose , Bastida Adolfo , Requena Alberto
Published: May 2023

In this paper, we study the quantum time evolution of oblique non-stationary vibrational states in a Hénon-Heiles oscillator system with two dissociation channels. The oblique non-stationary states we are interested in are the eigenfunctions of the anharmonic zeroth-order Hamiltonian operator resulting from the transformation to oblique coordinates, which are defined as those coming from non-orthogonal coordinate rotations that express the matrix representation of the second-order Hamiltonian in a block diagonal form characterized by the polyadic quantum number $n = n_1 + n_2$. The survival probabilities calculated show that the oblique non-stationary states evolve within their polyadic group with a high degree of coherence up to the dissociation limits on the short time scale. The degree of coherence is certainly much higher than that exhibited by the local non-stationary states extracted from the conventional orthogonal rotation of the original normal coordinates. We also show that energy exchange between the oblique vibrational modes occurs in a much more regular way than the exchange between the local modes.
Iridium-Catalyzed Enantioselective Formal α-Allylic Alkylation of Acrylonitrile
Authors: Roy Pankaj , Mukherjee Santanu
Published: May 2023

A highly enantioselective formal α-allylic alkylation of acrylonitrile is developed using 4-cyano-3-oxotetrahydrothiophene (c-THT) as a safe and easy-to-handle surrogate of acrylonitrile. This two-step process consists of an Ir/(P,olefin)-catalyzed branched-selective allylic alkylation using easily accessible branched rac-allylic alcohols as the allylic electrophile followed by retro-Dieckmann/retro-Michael fragmentation and is shown to be applicable for the enantioselective synthesis of α-allylic acrylates and α-allylic acrolein.
Enantioselective Nickel-Catalyzed Reductive Decarboxylative C(sp3)-C(sp2) Cross-Coupling of Malonic Acid Derivatives
Authors: Wang Jia-Bao , Fang Shuai-Shuai , Shen Yu , Liu Xiao-Ting , Li Ming-Hong , Shang Ming
Published: May 2023

The first enantioselective reductive decarboxylative C(sp3)-C(sp2) cross-coupling of malonic acid derivatives are reported via the intermediacy of redox-active esters (RAEs). A newly modified chiral bis-imidazoline ligand was identified as the optimal ligand to enable this reaction, providing direct access to valuable chiral aryl esters with high efficiency and excellent enantioselectivity. Our protocol is featured by its broad scope and exceptional compatibility with a variety of functional groups, even in the context of late-stage functionalization. In addition, C(sp2)−I could be selectively functionalized with bromo(iodo)arene. The detailed mechanistic studies supported a radical based cross-coupling mechanism.
Aptasensors: From fundamentals to new sensor concepts
Authors:   , Liu Ye
Published: May 2023

Aptamers are synthetic single-stranded (ss) oligonucleotides that bind to a broad range of targets, including cells, proteins, small molecules, toxins, metal ions, etc. with high affinity and selectivity. Aptasensors utilizing ssDNA and RNA aptamers as recognition elements have attracted significant attention in biosensing as aptamers possess excellent chemical stability, commercial availability with high purity and ease of modification with functional groups. Labeling aptamers with signal transduction groups such as fluorophores and redox markers have been extensively studied in biosensing research. However, covalent labeling processes always require complicated organic reaction, tedious preparation and separation, and expensive reagents. Thus, over the last decade, label-free aptasensors characterized by methods such as electrochemical impedance spectroscopy (EIS), surface plasmon resonance (SPR), colorimetry and fluorescence and so on have been widely developed and investigated. These efforts providing for the design of novel aptasensors, however, the lack of knowledge in understanding widely studied platforms still limits their applicability. Thus, more work is  required to study the fundamentals of crucial aptasensoring platforms enabling better design, build-up and data analysis. 
Vulnerabilidad humana ante la amenaza sísmica en el cantón Chimbo, provincia Bolívar
Authors: Iñiguez Gloria Piedad
Published: May 2023

En la historia contemporánea se menciona sistemáticamente a los sismos como un fenómeno natural de significativoimpacto social; que especialmente en escenarios urbanos, desencadenan una serie de trastornos en la vida cotidianadifíciles de predecir. El objetivo de la investigación es evaluar la vulnerabilidad humana ante la amenaza sísmica en elcantón Chimbo, provincia Bolívar; desde los entornos sociales, institucionales y culturales. La investigación es de enfoquemixto, de tipo no experimental, bajo una método alfa numérico. Los criterios aplicados se enmarcan en la selección deindicadores y parámetros de evaluación, análisis y ponderación mixta, así como la estimación del nivel de vulnerabilidad(alto, medio y bajo). Entre las metodologías consideradas se distinguen el de la Secretaría Nacional de Gestión Riesgo(SNGR) y el Programa de las Naciones Unidas para el Desarrollo (PNUD). La muestra estuvo compuesta por 430 sujetoshabitantes del casco urbano del cantón Chimbo y de las parroquias La Magdalena y La Asunción. Los resultados destacanque, en el cantón Chimbo se evidencian un nivel de vulnerabilidad media (62%) de las edificaciones. En la parroquiaMagdalena es media (61%) y en la Asunción media (71%). La vulnerabilidad social e institucional del casco urbano decantón Chimbo se encuentra en un nivel medio y, en las parroquias La Magdalena es alta y La Asunción media. Lasconclusiones detallan que la vulnerabilidad cultural en el casco urbano del cantón Chimbo es medio, debido a losconocimientos sobre la amenaza sísmica. En las parroquias La Magdalena y La Asunción, la vulnerabilidad cultural esalta, dado la insuficiente información de los informantes sobre las amenazas sísmicas existentes en cada zona.
representações sociais da educação física na formação docente
Authors: Triani Felipe da Silva , Cavalcanti Novaes Renato , De Cassio Costa Telles Silvio
Published: May 2023

Objetivou-se discutir as representações sociais da Educação Física na formação inicial de professores e suas associações com as subáreas biodinâmica, sociocultural e pedagógica. A pesquisa procurou observar se as representações sociais dos estudantes ingressantes são diferentes dos concluintes, sendo assim influenciadas pelo curso. Para atingir o objetivo da pesquisa, 220 estudantes, de três cursos de graduação em Educação Física da cidade do Rio de Janeiro, responderam ao Teste de Associação Livre de Palavras. Os resultados observados mostram que as representações sociais sobre Educação Física estão associados à subárea Biodinâmica para os ingressantes e para os concluintes, não havendo diferença no Núcleo Central das representações sociais na comparação entre os grupos A pesquisa concluiu que, independentemente do momento em que os alunos se encontravam, as representações sociais da Educação Física na formação de professores estão associadas à subárea biodinâmica e que, ao invés de fomentar a diversidade epistemológica, o curso parece estar reforçando a perspectiva biodinâmica da área.
Entre a ditadora da identidade e a maestrina da singularidade
Authors: Bogéa Diogo
Published: May 2023

Nesse trabalho apresentamos a noção de circunstância maestrina: uma prática artística capaz de reger a multiplicidade de impulsos e afetos que compõem uma pessoa. Partimos de uma ressignificação da noção de “humano” a partir da filosofia de Nietzsche, que apresenta o humano não mais como sujeito racional e consciente, mas como multiplicidade de impulsos, circunstâncias e afetos.
Pelo olhar do Miriti
Authors: Santos Tatiane Castro dos , Lucio Elizabeth Orofino
Published: May 2023

A pesquisa analisa as concepções de alfabetização e leitura que fundamentam o “Programa Tempo de Aprender” e suas implicações pedagógicas. Evidencia-se uma concepção de alfabetização restrita à aprendizagem do SEA e uma concepção de leitura como decodificação e extração de sentidos, o que significa um retrocesso.
Políticas para a formação de professores
Authors: Pagliarin Lidiane , Fávero Altair , Trevisol Marcio
Published: May 2023

Frente às últimas reformas na formação de professores, problematizamos: em que medida e sob quais concepções a formação inicial e continuada de professores prevista no PNE está sendo desenvolvida e como o PEE/RS e PEE/SC estão atingindo suas metas? A pesquisa é qualitativa, exploratória, documental, com análise comparada. Em síntese, concluímos que é preciso avançar para atingir as metas, assim como repensar intencionalidades das políticas de formação de professores a fim de superar o reducionismo neotecnicista presente nas atuais diretrizes nacionais de formação de professores.
Entre prescrições e práticas
Authors: Das Neves Júnior Pedro Carlos , Massaro Munique
Published: May 2023

Este ensaio teórico objetiva tecer reflexões sobre a inserção, nas práticas pedagógicas, em cursos de pedagogia, de uma educação que humaniza, emancipa o sujeito e promova condições para a inclusão educacional de pessoas com deficiência, mesmo que isto signifique resistir às normativas que tentam desmontar a educação. É apontado a emergência do abandono de concepções e metodologias na formação de professores que inibem e desumanizam os educandos.
lógica empresarial chega à escola
Authors: Evangelista Anderson Pereira , Melo Lúcia de Fátima
Published: May 2023

O texto analisa a atuação dos Institutos de Corresponsabilidade pela Educação (ICE), Natura (IN) e Sonho Grande (ISG) por meio da parceria público-privada firmada com o Governo do estado do Acre para implementar o Programa de Ensino Médio em Tempo Integral.
Da visibilidade ao apagamento
Authors: Albuquerque Olga Mirian Alves Pereira de , Dos Santos Nádson Araújo , Andrade Renata Cristina Lopes
Published: May 2023

Não é de hoje que o debate acerca da formação de professores merece destaque. Nos últimos anos, devido aos enfrentamentos em relação à apressada aprovação da Resolução CNE/CP 02/2019, particularmente em contraponto à conquistada Resolução CNE/CP 02/2015, a discussão se intensificou. Inserido nesse contexto, este artigo, ancorado na legislação e na literatura, considerando o questionamento – qual o espaço da formação de professores para a Educação de Jovens e Adultos (EJA) na Resolução CNE/CP n 02/2019? – busca analisar, comparar, refletir e problematizar sobre como a formação de professores e professoras para a Educação de Jovens e Adultos (EJA) encontra-se nas DCNs de 2015 e de 2019. Verificamos um retrocesso na formação de professores para a EJA com a aprovação acelerada da Resolução CNE/CP 02/2019, caracterizada por uma formação desarticulada, realizada de forma aligeirada, desconexa das formações continuadas e carecedora de políticas educacionais genuinamente formativas, ou seja, humanas, críticas e reflexivas.
Apresentação
Authors: Santos Nádson Araújo dos , Andrade Renata Cristina Lopes , Gonçalves Suzane da Rocha Vieira
Published: May 2023

O Dossiê Temático “Formação Docente: Políticas e Práticas sob a perspectiva Humana” traz as discussões e as reflexões de pesquisadores e pesquisadoras, nacionais e internacionais, do campo da Educação, acerca da Formação Docente, tanto em aspectos Políticos quanto em Práticos em uma perspectiva Humana. As leitoras e os leitores encontrarão uma coletânea de artigos subscritos por pesquisadores e pesquisadoras de referência, com reconhecidos predicados em relação à temática, os quais, considerando os distintos enfoques e olhares, problematizam, questionam e refletem e refratam sobre o importante, e urgente tema, a Formação Docente.
USE OF THE DEVELOPED AUTONOMOUS ROBOT SYSTEM “MOBILE BIOLOGIST” FOR STUDYING THE ANTARCTIC ECOSYSTEM
Authors: Fofanov D. V. , Semykina M. A.
Published: May 2023

The paper addresses the issues of using the developed autonomous robotic system to study the influence of water dynamics parameters on the density of Antarctic krill accumulations in traditional areas. With the help of this system, potentially vulnerable natural and ecological habitats of Antarctic krill can be identified, based on the data from which solutions for their conservation and stabilization can be proposed. An autonomous robotic system allows for such continuous monitoring to observe the basic trophic levels of ecosystems, the effects of changes in sea ice conditions, and other Antarctic environmental factors affecting the marine ecosystem. The application of the proposed method allows simultaneous measurements of environmental parameters in order to assess the relationship between the physical parameters of sea currents and biological processes. By integrating the system data with ship and satellite data in postprocessing, the response of Antarctic krill populations to multifactorial stresses can be assessed. The work was carried out according to the state assignment No. 0128-2021-0002 (“Mechanisms for the formation of the circulation structures of the World Ocean: key processes in the boundary layers and their role in ocean dynamics based on expeditionary studies, numerical and laboratory modeling”).
Do Cultural Capital and Conspicuous Consumption Influence Counterfeit Purchase Attitude? Evidence from Brazilian Market
Authors: Carvalho de Mesquita José Marcos , Moura Wenderson , Teixeira Dias Alexandre
Published: May 2023

This article analyses the influence of economic benefits, brand affection, cultural capital, and conspicuous consumption on the attitude toward counterfeit luxury products. A survey was carried out in places where these products are sold in the cities of Belo Horizonte and Nova Serrana, in the state of Minas Gerais, Brazil. The interviewees were divided into two groups (high and low cultural capital) and the data obtained were analyzed using Structural Equation Modeling. We found that brand affection, conspicuous consumption and cultural capital do not influence the attitude about counterfeit luxury products. Therefore, the economic benefit was the only factor capable of explaining the attitude. In comparative terms, the results were similar, but the economic benefits are more relevant for high cultural capital respondents.
Del auge a frustración: modernización y estancamiento en la economía kirchnerista
Authors: Rodríguez Leandro
Published: May 2023

Los vertiginosos años del proyecto kirchnerista (2003-2015) dejaron como legado, entre otras cosas, un desafío no poco relevante para los economistas heterodoxos. Al contrario de los aciagos tiempos del menemismo, abrumadoramente rechazados por el vasto campo del progresismo nacional, las políticas de los Kirchner generaron divisiones y posturas encontradas en el terreno del pensamiento no convencional. En efecto, se trata de explicar, sin apelar a los consabidos tópicos de la economía liberal-ortodoxa, los motivos de la frustración de un gobierno que decía promover el ansiado modelo de crecimiento con equidad. Pues bien, en el presente ensayo nos proponemos aportar a este debate mediante la recuperación, en un marco histórico-estructural, de una categoría conceptual de cuño estructuralista. Nos referimos a la noción de modernización elaborada oportunamente por Celso Furtado. El texto se funda, en términos metodológicos, en la indagación bibliográfica y en una construcción empírica ecléctica basada en fuentes de datos secundarios.
O ENSINO BÁSICO DE HISTÓRIA PARA JOVENS DURANTE A PANDEMIA DE COVID: EXPERIÊNCIAS DESENVOLVIDAS NO PROGRAMA DE RESIDÊNCIA PEDAGÓGICA EM TERESINA- PI
Authors: SANTOS DANIELLE FILGUEIRAS , Marinho Joseanne Zingleara Soares
Published: May 2023

O objetivo desse artigo é analisar as contribuições da aplicação de metodologias ativas no ensino de História para jovens da educação básica durante a pandemia de COVID- 19, considerando as experiências em sala de aula no contexto do Programa de Residência Pedagógica- PRP/CAPES, que foi desenvolvido em Teresina mediante a parceria com a Universidade Estadual do Piauí- UESPI. A participação ocorreu no exercício da docência na modalidade de residente a partir de atividades realizadas em turmas do Ensino Médio, no Colégio da Polícia Militar do Piauí- CPMP. O período foi marcado pela pandemia de COVID-19, que levou à adoção do sistema de ensino remoto e acentuou a necessidade de integração dos discentes no processo de ensino e aprendizagem. Nesse contexto, as metodologias ativas foram convertidas em ferramentas importantes para o ensino de História, pois puderam contribuir com uma maior efetividade da educação ao reduzir os impactos problemáticos ocasionados pela pandemia no contexto escolar.
ESCOLARIZAÇÃO E PRÁTICAS FAMILIARES: IMPACTOS DA CULTURA LETRADA SOBRE A INSTITUIÇÃO FAMILIAR ENTRE O FINAL DO SÉCULO XIX E INÍCIO DO SÉCULO XX
Authors: Miranda José da Cruz Bispo
Published: May 2023

Este trabalho analisa depoimentos orais e narrativas de memórias, nos quais alguns homens de letras, que viveram a juventude em Teresina, nas primeiras décadas do século XX, relatam suas trajetórias de vida marcadas pelo processo de escolarização, e pela busca de estreitar os laços com a cultura escrita e com as sociabilidades urbanas. São as formas como os homens constroem suas identidades vinculadas ao processo de escolarização e ao mundo de sociabilidades urbanas que se pretende trabalhar.
ENTREVISTA COM PROFª MSC. LUCIANA SOARES DA CRUZ
Authors: Magalhães Maria do Socorro Rios , Queiroz Teresinha de Jesus Mesquita , Rocha Dheiky do Rêgo Monteiro
Published: May 2023

Entrevista realizada com Luciana Soares da Cruz, graduada em História pela Universidade Estadual do Piauí e com especialização em História do Brasil pela Universidade Federal do Piauí - UFPI. É Mestre em Antropologia pelo Programa de Pós-Graduação em Antropologia da Universidade Federal do Piauí. Na edição número 4, volume 7 da revista Humana Res, ela conta um pouco sobre a relação entre antropologia e as subjetividades de crianças e adolescentes no âmbito da família e da escola. A entrevista é realizada pela Drª Maria do Socorro Rios Magalhães, Drª Teresinha de Jesus Mesquita Queiróz e Msc. Dheiky do Rêgo Monteiro Rocha.
MORHAN – PIAUÍ: 25 ANOS
Authors: Silva Gabriel Rocha da , Marcelo Neto
Published: May 2023

Resenha sobre o livro Morhan-Piauí: 25 anos escrito por Ruimar Batista em 2010, que expõe sobre as principais ações do movimento social ao longo dos anos. Além disso, o autor reflete sobre eixos temáticos que dizem respeito a movimentos sociais de maneira geral, situando o Morhan a partir desses debates.
A VIAGEM CIENTIFICA DE NEIVA E PENNA: SAÚDE E DOENÇA DE INFANTES NO PIAUÍ (1889-1930)
Authors: Barros Aricélia Soares
Published: May 2023

O artigo analisa as constituições e estratégias dos discursos higienistas, bem como as doenças das crianças no Piauí, no período de 1889 a 1930. Examina a o relatório de viagem cientifica dos médicos Arthur Neiva e Belizário Penna em sua passagem pelo Estado, especialmente nas discussões sobre a modernidade nacional e no que se refere ao movimento sanitarista, em seu discurso documentário, quanto as doenças das crianças locais e suas prescrições de cura no caminho narrativo considerando articulação do discurso com meio natural e social. A metodologia utilizada consistiu na sistematização de bibliografia relativa ao tema o relatório mencionado acima e análise do Almanaque da Farmácia dos Pobres, além de Mensagens e Relatórios governamentais.
EDUCAÇÃO INCLUSIVA: ESTRATÉGIAS PEDAGÓGICAS PARA ATENDER ALUNOS COM TEA
Authors: Oliveira Elisângela Maria Figueiredo de
Published: May 2023

O objetivo deste estudo foi analisar a adaptação de estratégias pedagógicas que possam ajudar no processo de aprendizagem de alunos com Transtorno de Espectro Autista (TEA), considerando as particularidades desse grupo e as dificuldades que enfrentam em sala de aula. Trata-se de uma pesquisa qualitativa, exploratório e de caráter transversal. Os resultados apontaram para a importância de práticas pedagógicas adaptadas, que considerem as particularidades dos alunos com TEA e possam proporcionar um ambiente de aprendizagem mais acolhedor e inclusivo. Essas práticas devem ser flexíveis e individualizadas, considerando as necessidades específicas de cada aluno. As estratégias pedagógicas adaptadas podem incluir o uso de recursos e a utilização de atividades lúdicas e sensoriais, a criação de rotinas e a definição de objetivos claros e concretos para a aprendizagem. Conclui-se, portanto, que a adaptação de estratégias pedagógicas é fundamental para o processo de aprendizagem de alunos com TEA, e que é preciso um esforço conjunto da escola, dos pais e dos profissionais para criar um ambiente de aprendizagem mais acolhedor e inclusivo para esses alunos.

Palavras-chave: TEA. Estratégias. Inclusão. Ensino. Aprendizagem.