bluuebunny/crossref_metadata_2025 huggingface dataset:
Type 2 Degenerate Poly-Euler Polynomials
Authors: Lee Dae , Kim Hye , Jang Lee-Chae
Published: June 2020

In recent years, many mathematicians have studied the degenerate versions of many special polynomials and numbers. The polyexponential functions were introduced by Hardy and rediscovered by Kim, as inverses to the polylogarithms functions. The paper is divided two parts. First, we introduce a new type of the type 2 poly-Euler polynomials and numbers constructed from the modified polyexponential function, the so-called type 2 poly-Euler polynomials and numbers. We show various expressions and identities for these polynomials and numbers. Some of them involving the (poly) Euler polynomials and another special numbers and polynomials such as (poly) Bernoulli polynomials, the Stirling numbers of the first kind, the Stirling numbers of the second kind, etc. In final section, we introduce a new type of the type 2 degenerate poly-Euler polynomials and the numbers defined in the previous section. We give explicit expressions and identities involving those polynomials in a similar direction to the previous section.
A Double Generally Weighted Moving Average Chart for Monitoring the COM-Poisson Processes
Authors: Chen Jen-Hsiang
Published: June 2020

Generalized exponentially weighted moving average (EWMA) and double EWMA (DEWMA) charts based on the Conway–Maxwell–Poisson (CMP or COM-Poisson) distribution, also known as the GEWMA and CMP-DEWMA charts, are effectively used for monitoring the counts of non-conformities in a process. To further enhance their performance, this study utilizes design and adjustment parameters to develop generally weighted moving average (GWMA) and double GWMA charts, also known as the CMP-GWMA and CMP-DGWMA charts, to monitor COM-Poisson attributes. Numerical simulations indicate that the CMP-DGWMA chart outperforms its prototype CMP-DEWMA and CMP-GWMA charts in detecting small location and dispersion shifts, as well as both shifts together, in terms of average run lengths. Finally, an example is provided to demonstrate the efficiency of the proposed CMP-DGWMA chart and its counterparts.
Per- and Polyfluoroalkyl Substances in Early Pregnancy and Risk for Preeclampsia: A Case-Control Study in Southern Sweden
Authors: Rylander Lars , Lindh Christian H. , Hansson Stefan R. , Broberg Karin , Källén Karin
Published: June 2020

Preeclampsia is one of the most common causes of perinatal and maternal morbidity/mortality. One suggested environmental risk factor is exposure to endocrine-disrupting pollutants such as per- and polyfluoroalkyl substances (PFAS). The present case-control study in southern Sweden aims to investigate the hypothesized association between serum concentrations of PFAS in early pregnancy and the risk of developing preeclampsia. The study included 296 women diagnosed with preeclampsia (cases) and 580 healthy pregnant women (controls). Maternal serum samples were obtained from a biobank of samples collected in early pregnancy in connection with screening for infections. Serum concentrations of perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), perfluorononanoic acid (PFNA), and perfluorohexane sulfonate (PFHxS) were analyzed using liquid chromatography-tandem-mass-spectrometry (LC/MS/MS). Among primiparous women, there were no differences in PFAS concentrations in early pregnancy between the cases and the controls whereas among multipara women, the cases had significantly higher concentrations of PFNA (median concentrations were 0.44 and 0.38 ng/mL, p = 0.04). When individual PFAS were categorized into quartiles and adjustment for potential confounders was performed, the women in the highest quartiles had no significant increased risks of developing preeclampsia as compared with women in the lowest category. In conclusion, the present study provides limited support for the hypothesized association between PFAS and preeclampsia in a population with relatively low exposure levels.
Editorial on the Special Issue “Comorbidities in Chronic Kidney Disease”
Authors: Noels Heidi , Jankowski Joachim
Published: June 2020

With a mean worldwide prevalence of 13 [...]
The Synergism of PGN, LTA and LPS in Inducing Transcriptome Changes, Inflammatory Responses and a Decrease in Lactation as Well as the Associated Epigenetic Mechanisms in Bovine Mammary Epithelial Cells
Authors: Wu Yongjiang , Sun Yawang , Dong Xianwen , Chen Jingbo , Wang Zili , Chen Juncai , Dong Guozhong
Published: June 2020

Mastitis is usually caused by a variety of pathogenic bacteria that include both Gram-positive and Gram-negative bacteria. Lipopolysaccharide (LPS) is the pathogen-associated molecular pattern (PAMP) of Gram-negative bacteria, and peptidoglycan (PGN) and lipoteichoic acid (LTA) are those of Gram-positive bacteria. The effects of LPS, PGN and/or LTA on inflammatory response and lactation in bovine mammary epithelial cells (BMECs) are well studied, but the epigenetic mechanisms of their effects received less attention. Furthermore, since the three PAMPs are often simultaneously present in the udder of cows with mastitis, it has implications in practice to study their additive effects. The results show that co-stimulation of bovine mammary epithelial cells with PGN, LTA, and LPS induced a higher number of differentially expressed genes (DEGs) and greater expressions of inflammatory factors including interleukin (IL)-1β, IL-6, IL-8, tumor necrosis factor-α (TNF-α), chemokine (C-X-C motif) ligand (CXCL)1, and CXCL6. In addition, co-stimulation further increased DNA hypomethylation compared with sole LPS stimulation. Co-stimulation greatly decreased casein expression but did not further decrease histone acetylation levels and affect the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC), compared with sole LPS stimulation. Collectively, this study demonstrated that PGN, LTA, and LPS had an additive effect on inducing transcriptome changes and inflammatory responses in BMECs, probably through inducing a greater decrease in DNA methylation. Co-stimulation with PGN, LTA, and LPS decreased casein expression to a greater degree, but it might not be linked to histone acetylation and HAT and HDAC activity.
Toxin-Antitoxin Systems: A Tool for Taxonomic Analysis of Human Intestinal Microbiota
Authors: Klimina Ksenia M. , Voroshilova Viktoriya N. , Poluektova Elena U. , Veselovsky Vladimir A. , Yunes Roman A. , Kovtun Aleksey S. , Kudryavtseva Anna V. , Kasianov Artem S. , Danilenko Valery N.
Published: June 2020

The human gastrointestinal microbiota (HGM) is known for its rich diversity of bacterial species and strains. Yet many studies stop at characterizing the HGM at the family level. This is mainly due to lack of adequate methods for a high-resolution profiling of the HGM. One way to characterize the strain diversity of the HGM is to look for strain-specific functional markers. Here, we propose using type II toxin-antitoxin systems (TAS). To identify TAS systems in the HGM, we previously developed the software TAGMA. This software was designed to detect the TAS systems, MazEF and RelBE, in lactobacilli and bifidobacteria. In this study, we updated the gene catalog created previously and used it to test our software anew on 1346 strains of bacteria, which belonged to 489 species and 49 genera. We also sequenced the genomes of 20 fecal samples and analyzed the results with TAGMA. Although some differences were detected at the strain level, the results showed no particular difference in the bacterial species between our method and other classic analysis software. These results support the use of the updated catalog of genes encoding type II TAS as a useful tool for computer-assisted species and strain characterization of the HGM.
Probing the Interactions of Ochratoxin B, Ochratoxin C, Patulin, Deoxynivalenol, and T-2 Toxin with Human Serum Albumin
Authors: Faisal Zelma , Vörös Virág , Fliszár-Nyúl Eszter , Lemli Beáta , Kunsági-Máté Sándor , Csepregi Rita , Kőszegi Tamás , Zsila Ferenc , Poór Miklós
Published: June 2020

Ochratoxins, patulin, deoxynivalenol, and T-2 toxin are mycotoxins, and common contaminants in food and drinks. Human serum albumin (HSA) forms complexes with certain mycotoxins. Since HSA can affect the toxicokinetics of bound ligand molecules, the potential interactions of ochratoxin B (OTB), ochratoxin C (OTC), patulin, deoxynivalenol, and T-2 toxin with HSA were examined, employing spectroscopic (fluorescence, UV, and circular dichroism) and ultrafiltration techniques. Furthermore, the influence of albumin on the cytotoxicity of these xenobiotics was also evaluated in cell experiments. Fluorescence studies showed the formation of highly stable OTB–HSA and OTC–HSA complexes. Furthermore, fluorescence quenching and circular dichroism measurements suggest weak or no interaction of patulin, deoxynivalenol, and T-2 toxin with HSA. In ultrafiltration studies, OTB and OTC strongly displaced the Sudlow’s site I ligand warfarin, while other mycotoxins tested did not affect either the albumin binding of warfarin or naproxen. The presence of HSA significantly decreased or even abolished the OTB- and OTC-induced cytotoxicity in cell experiments; however, the toxic impacts of patulin, deoxynivalenol, and T-2 toxin were not affected by HSA. In summary, the complex formation of OTB and OTC with albumin is relevant, whereas the interactions of patulin, deoxynivalenol, and T-2 toxin with HSA may have low toxicological importance.
Crystal Structure of Exotoxin A from Aeromonas Pathogenic Species
Authors: Masuyer Geoffrey
Published: June 2020

Aeromonas exotoxin A (AE) is a bacterial virulence factor recently discovered in a clinical case of necrotising fasciitis caused by the flesh-eating Aeromonas hydrophila. Here, database mining shows that AE is present in the genome of several emerging Aeromonas pathogenic species. The X-ray crystal structure of AE was solved at 2.3 Å and presents all the hallmarks common to diphthamide-specific mono-ADP-ribosylating toxins, suggesting AE is a fourth member of this family alongside the diphtheria toxin, Pseudomonas exotoxin A and cholix. Structural homology indicates AE may use a similar mechanism of cytotoxicity that targets eukaryotic elongation factor 2 and thus inhibition of protein synthesis. The structure of AE also highlights unique features including a metal binding site, and a negatively charged cleft that could play a role in interdomain interactions and may affect toxicity. This study raises new opportunities to engineer alternative toxin-based molecules with pharmaceutical potential.
PRMT5 Is Required for Bovine Leukemia Virus Infection In Vivo and Regulates BLV Gene Expression, Syncytium Formation, and Glycosylation In Vitro
Authors: Assi Wlaa , Hirose Tomoya , Wada Satoshi , Matsuura Ryosuke , Takeshima Shin-nosuke , Aida Yoko
Published: June 2020

Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, which is the most common neoplastic disease of cattle and is closely related to human T-cell leukemia viruses. We investigated the role of a new host protein, PRMT5, in BLV infection. We found that PRMT5 is overexpressed only in BLV-infected cattle with a high proviral load, but not in those with a low proviral load. Furthermore, this upregulation continued to the lymphoma stage. PRMT5 expression was upregulated in response to experimental BLV infection; moreover, PRMT5 upregulation began in an early stage of BLV infection rather than after a long period of proviral latency. Second, siRNA-mediated PRMT5 knockdown enhanced BLV gene expression at the transcript and protein levels. Additionally, a selective small-molecule inhibitor of PRMT5 (CMP5) enhanced BLV gene expression. Interestingly, CMP5 treatment, but not siRNA knockdown, altered the gp51 glycosylation pattern and increased the molecular weight of gp51, thereby decreasing BLV-induced syncytium formation. This was supported by the observation that CMP5 treatment enhanced the formation of the complex type of N-glycan more than the high mannose type. In conclusion, PRMT5 overexpression is related to the development of BLV infection with a high proviral load and lymphoma stage and PRMT5 inhibition enhances BLV gene expression. This is the first study to investigate the role of PRMT5 in BLV infection in vivo and in vitro and to reveal a novel function for a small-molecule compound in BLV-gp51 glycosylation processing.
The Identification of Factors Determining the Probability of Practicing Inland Water Tourism Through Logistic Regression Models: The Case of Extremadura, Spain
Authors: Sánchez-Rivero Marcelino , Rodríguez-Rangel Mª Cristina , Fernández-Torres Yakira
Published: June 2020

Inland water tourism is put forward as a highly sustainable and attractive tourism product owing to its ability to generate economic development, raise awareness of respect for the environment, and contribute towards the diversification necessary to alleviate overexposure in coastal areas. For this reason, territories with sufficient expanses of water increasingly strive to create tourist products which allow them to enjoy the benefits associated with this type of tourism. The case of the region of Extremadura in Spain deserves special attention due to the abundant presence of lake resources which allows it to find an opportunity to stand out in inland water tourism and promote economic development. The initial objective of this research is the generation of knowledge of the demand currently existing in the territory. In order to do so, a logit regression model is used based on 4625 surveys collected in 2017. This model is later verified by means of a Chow test so as to analyze which factors influence the probability of practicing inland water tourism, paying attention to certain control variables such as the season or the tourist market. The results obtained have important implications for tourism managers and the establishment of a suitable development policy strategy.
Constructed Wetlands for Sustainable Wastewater Treatment in Hot and Arid Climates: Opportunities, Challenges and Case Studies in the Middle East
Authors: Stefanakis Alexandros
Published: June 2020

Many countries and regions around the world are facing a continuously growing pressure on their limited freshwater resources, particularly those under hot and arid climates. Higher water demand than availability led to over-abstraction and deterioration of the available freshwater resources’ quality. In this context, wastewater, if properly treated, can represent a new water source added in the local water balance, particularly in regions of Colorado, California, Australia, China and in the wide region of the Middle East, which is characterized as one of most water-stressed regions in the world. This article summarizes the status of wastewater treatment and management in the Middle East and discusses the challenges, the various barriers and also the opportunities that arise by introducing the sustainable technology of Constructed Wetlands in the region. Furthermore, the aim of the article is to provide a better insight into the possibility and feasibility of a wider implementation of this green technology under the hot and arid climate of Middle East by presenting several successful case studies of operating Constructed Wetlands facilities in the region for the treatment of various wastewater sources.
Simulation Study on the Different Policies of Jiangsu Province for a Dynamic Balance of Water Resources under the Water–Energy–Food Nexus
Authors: Chen Yan , Chen Weizhong
Published: June 2020

In order to promote the efficient use of resources and the sustainable development of the economy in Jiangsu Province, it is particularly important to ease the contradiction between water supply and demand on the basis of realizing the coordinated development of the water–energy–food (WEF) nexus. With the aim of a dynamic balance of water resources, this paper used system dynamics (SD) to build a WEF nexus SD model that focused on studying the specific supply-and-demand mechanism of water resources in each subsystem. Then, Jiangsu Province was taken as an example to perform simulation research on the regional water dynamic balance to explore effective policies for increasing water supply and decreasing water demand. The results showed that the imbalance of water resources will remain severe in the next few years. To relieve the imbalance, it will be helpful to promote the energy utilization of straw, improve the irrigation efficiency, adjust the crop planting structure, and require residents to strictly follow the water quota. An important advancement in this study is the simulation of the water resources supply-and-demand mechanism in each subsystem from the perspective of the WEF nexus.
Dissolved Radiotracers and Numerical Modeling in North European Continental Shelf Dispersion Studies (1982–2016): Databases, Methods and Applications
Authors: Bailly du Bois Pascal , Dumas Franck , Voiseux Claire , Morillon Mehdi , Oms Pierre-Emmanuel , Solier Luc
Published: June 2020

Significant amounts of anthropogenic radionuclides were introduced in ocean waters following nuclear atmospheric tests and development of the nuclear industry. Dispersion of artificial dissolved radionuclides has been extensively measured for decades over the North-European continental shelf. In this area, the radionuclide measurement and release fluxes databases provided here between 1982 and 2016 represent an exceptional opportunity to validate dispersion hydrodynamic models. This work gives accessibility to these data in a comprehensive database. The MARS hydrodynamic model has been applied at different scales to reproduce the measured dispersion in realistic conditions. Specific methods have been developed to obtain qualitative and quantitative results and perform model/measurement comparisons. Model validation concerns short to large scales with dedicated surveys following the dispersion: it was performed within a two- and three-dimensional framework and from minutes and hours following a release up to several years. Results are presented concerning the dispersion of radionuclides in marine systems deduced from standalone measurements, or according to model comparisons. It allows characterizing dispersion over the continental shelf, pathways, transit times, budgets and source terms. This review presents the main approaches developed and types of information derived from studies of artificial radiotracers using observations, hydrodynamic models or a combination of the two, based primarily on the new featured datasets.
Multivariate Monitoring of Surface Water Quality: Physico-Chemical, Microbiological and 3D Fluorescence Characterization
Authors: Daou Claude , El Hoz Mervat , Kassouf Amine , Legube Bernard
Published: June 2020

The primary objective of this study is to explore a water quality database on two Mediterranean rivers (the Kadisha-Abou Ali and El Jaouz rivers—located in north Lebanon), considering their physicochemical, microbiological and fluorescence characteristics. Principal Component Analysis (PCA) was applied to the matrix gathering physicochemical and microbiological data while the Common Components and Specific Weight Analysis (CCSWA) or ComDim was used for fluorescence excitation-emission matrices (EEMs). This approach provided complementary and valuable information regarding water quality in such complex ecosystem. As highlighted by the PCA and ComDim scores, the Kadisha-Abou Ali River is highly influenced by anthropogenic activities because its watershed districts are intensively populated. This influence reveals the implication of organic and bacteriological parameters. To the contrary, the El Jaouz watershed is less inhabited and is characterized by mineral parameters, which determines its water quality. This work highlighted the relationship between fluorescence EEMs and major water quality parameters, enabling the selection of reliable water quality indicators for the studied rivers. The proposed methodology can surely be generalized to the monitoring of surface water quality in other rivers. Each customized water quality fingerprint should constantly be inspected in order to account for any emerging pollution.
Effect of Microhabitat Structure on the Distribution of an Endangered Fish, Coreoperca kawamebari (Temminck & Schlegel, 1843) in the Geum River, South Korea
Authors: Choi Jong-Yun , Kim Seong-Ki , Kim Jeong-Cheol , Yun Jong-Hak
Published: June 2020

Macrophytes play a major role in the structuring of aquatic environments and may influence the distribution and feeding habits of fish species. We explored the microhabitat characteristics influencing the spatial distribution of newly discovered Coreoperca kawamebari (Temminck & Schlegel, 1843) in the upstream reaches of the Geum River. Out of 21 study sites, C. kawamebari was found in 10 sites, and its abundance was strongly positively correlated with “vegetated” microhabitats, especially those covered by elodeids (e.g., Ceratophyllum demersum). The utilization of elodeids by the piscivores fish, C. kawamebari, may limit the abundance of other native fishes, and stable isotope analysis also showed that C. kawamebari is likely to consume other fish species. However, the influence of other fish species on C. kawamebari is assumed to be small, considering that C. kawamebari is a latent predator. Although the abundance of other fish was low within the preferred microhabitat of C. kawamebari, other species were abundant in each site where C. kawamebari was dominant. From this finding, we conclude that the successful settlement of C. kawamebari in the upper section of the Geum River can be attributed to their habitat preferences. Although the elodeids favored by C. kawamebari generally have difficulty developing in the upstream section, the habitat creation by humans has contributed to the stable settlement of new fish species.
Driving Forces Analysis of Non-structural Carbohydrates for Phragmites australis in Different Habitats of Inland River Wetland
Authors: Jiao Liang , Zhou Yi , Liu Xuerui , Wang Shengjie , Li Fang
Published: June 2020

Habitat variation in non-structural carbohydrates (NSC) reflects the resource allocation trade-offs for clonal plants, and its driving force analysis embodies the ecological adaptation strategy of clonal plants to heterogeneous environments. In this paper, the reed (Phragmites australis) in the northwestern inland wetlands of China, as a typical example of clonal plants, was used as the research object. The content and distribution of NSC in reeds and their response characteristics to soil environmental factors were compared under three different environmental gradients with wet, salt marsh and desert habitats. The results showed: (1) the content of NSC and starch gradually increased and the content of soluble sugar gradually decreased from wetland to desert habitats, and the ratio of soluble sugar to starch increased significantly (p < 0.05), which demonstrated that reeds converted more NSC into starch to adapt to harsh environments as the environment changed. (2) Reeds tended to invest more NSC in underground architectures to achieve survival and growth with the increase in environmental stress, providing the evidence that NSC were transferred from leaf to rhizome, and root, stem and rhizome received more soluble sugar investment. The ratio of soluble sugar to starch of reed stem and rhizome increased significantly with the increasing content of soluble sugar and the decreasing content of starch, and more starch was converted into soluble sugar to resist the harsh environment. (3) Soil water, soil bulk density and salinity were the main driving forces for the NSC content and the distribution characteristics of reeds using the relative importance analysis. The study results clarified the habitat variation law, and the main environmental driving forces of NSC for reeds in inland river wetlands, which provided the significant references for enriching the ecology research theory of clonal plants and protection measures in the fragile and sensitive wetlands in arid regions.
Prediction of Mean Wave Overtopping Discharge Using Gradient Boosting Decision Trees
Authors: den Bieman Joost P. , Wilms Josefine M. , van den Boogaard Henk F. P. , van Gent Marcel R. A.
Published: June 2020

Wave overtopping is an important design criterion for coastal structures such as dikes, breakwaters and promenades. Hence, the prediction of the expected wave overtopping discharge is an important research topic. Existing prediction tools consist of empirical overtopping formulae, machine learning techniques like neural networks, and numerical models. In this paper, an innovative machine learning method—gradient boosting decision trees—is applied to the prediction of mean wave overtopping discharges. This new machine learning model is trained using the CLASH wave overtopping database. Optimizations to its performance are realized by using feature engineering and hyperparameter tuning. The model is shown to outperform an existing neural network model by reducing the error on the prediction of the CLASH database by a factor of 2.8. The model predictions follow physically realistic trends for variations of important features, and behave regularly in regions of the input parameter space with little or no data coverage.
The Link between Permeable Interlocking Concrete Pavement (PICP) Design and Nutrient Removal
Authors: Liu Bodi , Armitage Neil
Published: June 2020

The construction of ‘hard’ impermeable surfaces in urban areas results in the increased flow of stormwater runoff and its associated pollutants into downstream receiving waters. Permeable Pavement Systems (PPS) can help mitigate this. The most common type of PPS in South Africa is permeable interlocking concrete pavement (PICP), but there is currently insufficient information available on the relative treatment performance of different PICP designs. This paper describes an investigation into the performance of ten different PICP systems constructed in the Civil Engineering Laboratory at the University of Cape Town for the treatment of various nutrients commonly found in stormwater runoff. It was found that removal efficiencies ranged from 27.5% to 78.7% for ammonia-nitrogen and from −37% to 11% for orthophosphate-phosphorus; whilst 4% to 20.2% more nitrite-nitrogen and 160% to 2580% more nitrate-nitrogen were simultaneously added. The presence of a geotextile resulted in higher ammonia-nitrogen removal efficiencies but also higher nitrate-nitrogen addition than those cells without—with small differences between various types. The cell with a permanently wet ‘sump’ had the highest nitrate-nitrogen addition of all. Lower pH results in higher nitrate-nitrogen concentrations, whilst the electrical conductivity strongly depends on the length of the periods between rainfall ‘seasons’, decreasing rapidly during wet periods but increasing during dry periods. Paver type also had a minor impact on nutrient removal.
Yabancı Dil Sınıf Kaygısı Ölçeği’nin Faktör Yapısının İncelenmesi
Authors: ORUÇ Eylem , DEMİRCİ Cavide
Published: June 2020

Yabancı dil kaygısı, dil öğrenme sürecini etkileyen bireysel faktörlerden biri olarak uzun yıllardır araştırmalara konu olmaktadır. Çalışmada, Yabancı Dil Kaygısı Ölçeği’nin faktör yapısının Türkiye bağlamında incelenmesi amaçlanmıştır. Araştırmanın çalışma grubunu 2017-2018 eğitim-öğretim yılı bahar döneminde Marmara Bölgesindeki bir üniversitenin İngilizce hazırlık bölümde öğrenim gören 166 öğrenci oluşturmuştur. Geçerlilik güvenirlik çalışması, dil geçerliği, puanlandırma, uygulama, madde analizi, yapı geçerliği ve güvenirlik basamaklarından oluşmaktadır. Araştırma sonucunda, Yabancı Dil Sınıf Kaygısı Ölçeği’nin konuşma kaygısı, başarısızlık kaygısı ve özgüven eksikliği olmak üzere 3 boyuttan oluşan bir faktör yapısına sahip olduğuna ulaşılmıştır. Açımlayıcı faktör analizi sonuçlarına göre faktörlerin toplam varyansın %57’sini açıkladığı saptanmıştır. Ölçeğin güvenirliğine ilişkin uygulanan iç tutarlılık analizi sonucunda konuşma kaygısı, başarısızlık kaygısı ve özgüven eksikliği faktörlerinde iç tutarlılık katsayısının kabul edilebilir değerler aldığı belirlenmiştir. Buna göre, bu çalışmada Yabancı Dil Sınıf Kaygısı Ölçeği’nin çoklu faktör yapısı Türkiye bağlamında incelenmiş ve yabancı dil kaygısının ölçülmesinde kullanılabilecek güvenilir ve geçerli bir araç olarak değerlendirilmiştir.
On the need for revising the Code of Practice CP 32.13330.2018 «Sewerage. Pipelines and wastewater treatment plants» regarding the design of systems for the disposal and treatment of surface runoff from settlements
Authors: Верещагина Л.М.
Published: June 2020

Обсуждается нормативная база проектирования систем отведения и очистки поверхностных сточных вод с территории поселений и площадок предприятий, в частности практика применения свода правил СП 32.13330.2018 «Канализация. Наружные сети и сооружения. СНиП 2.04.03-85», введенного в действие приказом Минстроя России с 26 июня 2019 г. Рассматриваются структурные изменения нормативного документа, а также наиболее часто встречающиеся проблемы, с которыми приходится сталкиваться проектным организациям и органам Государственной экспертизы проектов в результате применения его отдельных положений при проектировании инженерных сооружений системы отведения и очистки поверхностных сточных вод с территории поселений. Приводится перечень основных пунктов СП 32.13330.2018, требующих пересмотра, даются комментарии к ним.

The regulatory framework for the design of systems for the disposal and treatment of surface runoff from the territory of settlements and industrial sites is discussed, in particular, the practice of applying the Code of Practice CP 32.13330.2018 «Sewerage. Pipelines and wastewater treatment plants. SNiP 2.04.03-85», enforced by the order of the RF Ministry of Construction of June 26, 2019. Structural changes of the regulatory document are considered, as well as the most common problems that design organizations and the state authorities of project expertise have to face while applying separate provisions in designing engineering structures for disposal and treatment of surface runoff from settlements. A list of the main paragraphs of CP 32.13330.2018 that require revision with the respective comments is presented.
Analysis of the Influence of Workload and Work Environment on Employee Turnover at PT. XYZ
Authors: Wibowo Teguh Setiawan , Cakranegara Pandu Adi , Putra I Gusti Ngurah Agung Dewantara , Saputra Eka Kurnia , Amalia Mekar Meilisa
Published: June 2020

The purpose of this study was to analyze the influence of workload and work environment on employee turnover at PT. XYZ. The research design used in this study used quantitative associative methods. Based on the results of data analysis that has been carried out in the first hypothesis (H1), the value of t count > t table is 11,892 > 1,678 and in the second hypothesis (H2) the value of t count > t table is 13,968 > 1,678 which means that the workload and work environment has a positive and significant effect on employee turnover at PT. XYZ while the R-square value obtained is 0.869 which states that the workload and work environment variables affect employee turnover at PT. XYZ is 86.90% and the remaining 13.10% is influenced by other variables.
Factors Affecting Repurchase Intention of Digital Products on Online Games in Indonesia
Authors:   Student of Universitas Bina Nusantara, Indonesia., Wibowo David Chandra Sukma , Simanjuntak Dr. Evi Rinawati ,   Faculty Member of Universitas Bina Nusantara, Indonesia.
Published: June 2020

Today more and more gamers purchase digital products on the online game. Therefore, the study was conducted to determine the factors that influence repurchase intention on digital online game items on the official website. Factors studied were system, service, and information quality on repurchase intention through utilitarian & hedonic shopping value and customer satisfaction. The data processed through validation, reliability and SEM analysis. From the results the most influence is information quality, where this affects hedonic & utilitarian shopping value, then leads to customer satisfaction and finally to repurchase intention. Based on the results the managerial implication is focused on increasing information with currency dimensions and system quality with accessibility dimensions to increase repurchase intention to purchase digital products.
Maximal Covariance Complexity-Based Penalized Likelihood Method in High Dimensional Data
Authors:   Department of Mathematics, Faculty of Science, Universiti Teknologi Malaysia 81310 UTM Skudai, Johor, Malaysia. 2 Department of Mathematics and statistics Nuhu Bamalli Polytechnic p.m.b 1061, Zaria Correspondence., Kargi Isah Aliyu , Ismail Norazlina Bint ,   Department of Mathematics, Faculty of Science, Universiti Teknologi Malaysia 81310 UTM Skudai, Johor, Malaysia., Mohamad Ismail Bin ,   Department of Mathematics, Faculty of Science, Universiti Teknologi Malaysia 81310 UTM Skudai, Johor, Malaysia.
Published: June 2020

Classification of cancer and selection of genes is one of the most important application of DNA microarray data. As a result of the higher dimensionality of microarray data, classification and selection of gene techniques are frequently employed to support the professional systems in the diagnosing ability of cancer with higher precision in classification. Least absolute shrinkage and selection operator (LASSO) is one of the most popular method for cancer classification and gene selection in high dimensional data. However, Lasso has limitations of being biased and cannot select variables more than the sample size (n) in gene selection and classification of high dimensional microarray data. To address this problems, LASSO-C1F was proposed using scale invariant measure of maximal information complexity of covariance matrix denoted with weight modifications as data-adaptive alternative to the fairly arbitrary choice of the regularization term in the least absolute shrinkage and selection operator (LASSO). The results indicated the effectiveness of the proposed method LASSO-C1F over the classical LASSO. The evaluation criteria result shows that the proposed method, LASSO-C1F has a better performance in terms of AUC and number of genes selected.
Public Relations Strategy in the use of Management Information Systems to Improve the Work of Institution
Authors:   College of Mass Communication and Public Relations / University of Fujairah / Emirate of Fujairah / United Arab Emirates, Abdalaziz* Dr. Maha Mustafa Omer
Published: June 2020

The aim of the research is to shed light on public relations strategies in the use of information systems to improve the work of institutions as an information behavior that makes a distinction in adding new value in various ways to improving the work of institutions. To this is to identify the analysis and evaluation of the effects of the use of management information systems in identifying problems and difficulties and their importance for managing public relations in revealing strategies that public relations can follow in government or private institutions in making strategic decisions leading to plans and directions for dealing with the public of institutions, and developing systems programs Administrative information according to international standards for administrative work; to enhance the image of institutions in their vision and the goals of their institutional work plan leading to an integrated understanding and scientific information of the best ways and techniques to simplify the work in addition to groups of strategies Basic final. In light of this, the subject of the research deals with the strategy of public relations in the use of management information systems to improve work in institutions, and the way in which support, decision-making and directions are contributed by the Department of Public Relations in institutions, in the use of administrative information in the organization of work as a major goal highlighting the importance of the information strategy; in addition to developing The procedures followed and communication mechanisms in developing the management level of institutions, to facilitate communication with its external partners.
Health Facilities in Kokrajhar District of Assam, India
Authors:   Guest Lecturer, Department of Geography, Gossaigaon College, Gossaigaon, Kokrajahr, Assam, India, Mushahary Gwmsath , Basumatary Dr. Manjil ,   Teacher, Department of Geography, Gossaigaon College, Gossaigaon, Kokrajahr, Assam, India.
Published: June 2020

Health can be considered as the state of being free from illness or injury. A health facility is a facility where quality health care access is provided. The number and quality of health facilities in a country or region is common measures of that area’s prosperity and quality of life. Therefore, health infrastructure is one of socio economic indicators of an area. As per the guideline of the WHO, the Doctor Population ratio should be 1:1000 but in case of India it is very pathetic as the ratio stands at 1:1456 (Economic survey 2019-20) and the state of Assam is more pathetic i.e 1:1800. A health status of a region is dependent on the health care availability provided in the region. The district Kokrajhar is situated in the westernmost part of Assam and is lacking far behind in health care facilities as compared to other districts of the state. Most of the families belong to the Below Poverty Line (BPL) category and their PCI is also one of the lowest. The reason for poor health care facilities in the district is mainly because of Doctors unwillingness to join the government services and their reluctance to serve in the rural areas. The main objective of this paper is to highlight the health facilities and health status of the district in comparison to the state and the country. The study is based on the secondary data sources and both descriptive and analytic methods have been used for the study. Statistical techniques are also used to represent the data. The study reveals that the causes of low status of health facilities in the region is due to lack of accessibility, poverty, insufficient medical equipment and insufficient workforce and cultural norms and due to all this, people of the district is facing many problems. The diseases like Typhoid, Jaundice, Eye problem, Malaria, Tuberculosis, Pneumonia etc are commonly seen in the district. . This study will aid the governments, NGOs, planners, administrators and above all the society as the research work highlights some of the hidden truths pertaining to health care facilities in the district.
Use of Road Stabilizers in Sensitive Environments
Authors:   Technical Director, SLR Consulting (UK) Ltd, McKendry P
Published: June 2020

Road infrastructure is key for any developing country to enable its expansion such as those in Africa. Natural road construction materials can become depleted and increasing traffic loads produce higher maintenance requirements, leading to research to develop additives that can be used to enhance the engineering properties of available pavement soils. Providing all weather roads for large vehicles in rural areas, such as Northern Namibia, are often based only on the available soils, involving compaction and use of stabilizers, is required to both provide a suitable load bearing road surface and maintain the road network. The region is also environmentally sensitive to any potentially adverse impacts of chemicals that may be released into the environment during construction or as breakdown products. A number of road stabilizer products are available and the choice of stabilizer must take into account both its specific properties and the sensitivity of the environment where it is to be used to any environmental impacts. The main stabilizer types are cementitious, bituminous and chemical, with the latter broken down in a range of materials including synthetic polymer binders, organic and ionic compounds, salts, enzymatic products and combinations thereof. Twenty available stabilizer products were considered in terms of their environmental properties and assessed against the published literature and the general findings reported in terms of the overall ranking of the environmental impact of stabilizer types.
The Effect of Advertising Attraction and Brand Embassy on Shopee Purchase Decisions
Authors:   Department of Financial And Banking Administration, Perbanas Institute Of Marketing Management, Jakarta, Indonesia., Nabilah Farras
Published: June 2020

Through the development of technology and the increasing number of internet usage at this time, it is very interesting that many various business businesses to market their products through e-commerce, resulting in considerable business competition for participating companies. In e-commerce business competition, companies use various marketing strategies related to communication, one of which is advertising, because advertising attracts many consumers to see their products on the e-commerce site. In the use of advertising strategies, companies must have a variety of creative concepts in pairing their advertisements, one of which is by requiring ad stars who will present their products to consumers who can be said to be brand ambassadors. Companies must be smart in choosing brand ambassadors who will be used as weapons to market their products in these advertisements, in order to attract many consumers to view these products and buy them. So, the appeal of advertising and brand ambassadors is very important in making purchasing decisions. Because of the existence of attractive advertisements and brand ambassadors that can attract consumers to buy makes the company's best strategy to market its products. The research I did was to analyze the effect of ad appeal on Shopee's online purchasing decisions and also analyze the influence of brand ambassadors on Shopee's online purchasing decisions. The method used in this study is a survey method with a questionnaire as primary data. The results of research that uses the attractiveness of advertising and brand ambassadors find that the attractiveness of advertisements has a significant effect on purchasing decisions and brand ambassadors also show a significant influence on purchasing decisions. So it can be concluded that advertising and brand ambassadors have a very important role in the company's strategy in marketing its products.
Educational and Psychological Impacts of Corona-phobia and Movement Control Order
Authors:   Educational Foundations, Sokoto State University, Sokoto, Nigeria., Bashar* Sa’adu Isa , Maiwada Ramatu M. ,   Educational Foundations, Sokoto State University, Sokoto, Nigeria, Inda Abdulmumini ,   Department of Arts Education, Faculty of Education Taraba State. Nigeria
Published: June 2020

Covid19's pandemic outbreak has dwarfed the global community to its knees so that the world was enveloped by panic, uncertainty and confusion. The quest for measures to control the plague has remained a challenging priority for each nation. Some of the world's most popular measures include restricting the movement of peoples, social distancing and isolation. Such tactics have created a great deal of mayhem, crises, and ultimately influence all social life interests including schooling, economy, religion and others. This study seeks to examine the educational and psychological impacts of Corona-phobia and the Movement Control Order (MCO) rule on Nigerian graduate students in Universiti Teknologi Malaysia (UTM). The study was quantitative, consisting as its population of all 380 postgraduate students. A sample of 191 participants was randomly selected with reference to guidelines from Krejcie and Morgan. Also developed and distributed among the respondents was a questionnaire whose validity and reliability were 0.7 and 0.8 respectively. Findings revealed that Corona-phobia and Movement Control Order developed fear, hopelessness and stigmatization coupled with denial of access to physical library, laboratory facilities, academic consultations, and conducting excursion functions. It is recommended among other things that the UTM authorities should introduce online services, academic activities and programmes to enable E-lectures, E-exams, E-supervision, E-submission of thesis, E-proposal defense, E-viva presentation, E-approvals, E-corrections, E-visa renewal, and E-visa cancellation etcetera. These will ensure continuity of the educational programmes during the pandemic period and will reduce the boredom, anxiety and depression among students.
Come si abbrevia, come si scrive e come si legge “24 ore su 24”?
Authors: Coletti Vittorio
Published: June 2020

Una lettrice ci chiede quale sia l’abbreviazione da scegliere per indicare un servizio aperto 24 ore su 24, tra 24/24, h24 o 24h su 24; un’altra domanda se sia corretto leggere h24 come “acca ventiquattro” anziché “ventiquattrore”.
It may be time to improve the neuron of artificial neural network
Authors: Liu Gang
Published: June 2020

Artificial neural networks (ANNs) have won numerous contests in pattern recognition, machine learning, and artificial intelligence in recent years. The neuron of ANNs was designed by the stereotypical knowledge of biological neurons 70 years ago. Artificial Neuron is expressed as f(wx+b) or f(WX). This design does not consider dendrites’ information processing capacity. However, some recent studies show that biological dendrites participate in the pre-calculation of input data. Concretely, biological dendrites play a role in extracting the interaction information among inputs (features). Therefore, it may be time to improve the neuron of ANNs. In this study, some dendritic modules with excellent properties are proposed and added to artificial neurons to form new neurons named Gang neurons. E.g., The dendrite function can be expressed as Wi,i-1Ai-1 ○ A0|1|2|...|i-1 . The generalized new neuron can be expressed as f(W(Wi,i-1Ai-1 ○ A0|1|2|...|i-1)).The simplified new neuron be expressed as f(∑(WA ○ X)). After improving the neurons, many networks can be tried. This paper shows some basic architecture for reference in the future. Up to now, others and the author have applied Gang neurons to various fields, and Gang neurons show excellent performance in the corresponding fields.

Interesting things: (1) The computational complexity of dendrite modules (Wi,i-1Ai-1 ○ Ai-1) connected in series is far lower than Horner's method. Will this speed up the calculation of basic functions in computers? (2) The range of sight of animals has a gradient, but the convolution layer does not have this characteristic. This paper proposes receptive fields with a gradient. (3) The networks using Gang neurons can delete Fully-connected Layer. In other words, the parameters in Fully-connected Layers are assigned to a single neuron, which reduces the parameters of a network for the same mapping capacity. (4) ResDD(ResDD modules+One Linear module) can replace the current ANNs’ Neurons. ResDD has controllable precision for better generalization capability.

Gang neuron code is available at https://github.com/liugang1234567/Gang-neuron.
VIBRATRION LOADS REDUCE ON THE LARGE AIRSHIPS AND AIRCRAFT WITH MORE ELECTRICAL ENGINES
Authors: Ponyaev Leonid , Kuprikov Mikhail , Kuprikov Nikita
Published: June 2020

The analysis of the find Optimal Structure of the Large Aircraft and Airship for decrease of Frame Vibration Level with Aeroelastic Active Electric Demphers are very actually today for Worldwide Ecology Program. The paper analyzes the promising of Development directions of Modern Air Transport Systems with use the Disc Shaped Airship (DSA) type Thermoplan MAI. The estimation of the profitability of Disk Shaped Electric Vehicles for the Optimal Aerodynamic and Weight Efficiency Design & Manufactory in comparison with other forms for High-Altitude Stratospheric & Orbital Complex as Astronomical Observatories and the implementation of Aerospace Launches & Landings.