bluuebunny/crossref_metadata_2025 huggingface dataset:
Current Insights into Carpal Tunnel Syndrome: Clinical Strategies for Prevention and Treatment
Authors: Chaudhary Rishabh , Khanna Janvi , Bansal Seema , Bansal Nitin
Published: February 2024

Background:

Carpal tunnel syndrome (CTS) is a condition that is caused by medial nerve compression, resulting in symptoms such as numbness, tightness, or weakness in the hand.

Objectives:

The aim of the study was to find out the genetic modulation, mechanism, available treatment, and recommendation for carpal tunnel syndrome at its specific stage.

Methods:

Almost 200 papers were searched for this review article, and 145 articles were selected. The literature was collected from different sources like Google scholar, PubMed, a directory of open-access journals, and science.gov by using keywords, such as treatment, risk factors, recommendation, and clinical features of carpal tunnel syndrome.

Results:

The most efficient non-surgical treatment is methylprednisolone acetate, which reduces inflammation by acting on the glucocorticoid receptor in conjunction with immunofilling. It has also been used successfully as a second-line drug for the treatment of patients with mild or moderate conditions in order to provide relief. New non-pharmacological options include laser therapy in acupuncture, transcutaneous electric nerve stimulation (TENS), and sham therapy. Modern treatments like TENS, laser therapy, splints, and injections of methylprednisolone acetate have been demonstrated to be helpful in sporadic situations. For patients with mild and moderate problems, more research should be conducted that includes the combination of these surgical and non-surgical treatments.

Conclusion:

We propose a multifunctional panel construct and define standard data items for future research into carpal tunnel syndrome. A discussion on idiopathic carpal tunnel syndrome, risk factors, combination of therapies, using guidelines-based recommendations and treatment should be initiated.
Dietary Plant Metabolites Induced Epigenetic Modification as a Novel
Strategy for the Management of Prostate Cancer
Authors: Singh Vaibhav , Shirbhate Ekta , Kore Rakesh , Mishra Aditya , Johariya Varsha , Veerasamy Ravichandran , Tiwari Amit K , Rajak Harish
Published: February 2024

Prostate cancer is a widespread malignancy among men, with a substantial global impact
on morbidity and mortality. Despite advances in conventional therapies, the need for innovative and
less toxic treatments remains a priority. Emerging evidence suggests that dietary plant metabolites
possess epigenetic-modifying properties, making them attractive candidates for prostate cancer
treatment. The present work reviews the epigenetic effects of dietary plant metabolites in the context
of prostate cancer therapy. We first outline the key epigenetic mechanisms involved in prostate cancer
pathogenesis, including histone modifications, DNA methylation, and miRNA or Long Noncoding
RNA (lncRNA) dysregulation. Next, we delve into the vast array of dietary plant metabolites
that have demonstrated promising anti-cancer effects through epigenetic regulation. Resveratrol,
minerals, isothiocyanates, curcumin, tea polyphenols, soy isoflavones and phytoestrogens, garlic
compounds, anthocyanins, lycopene, and indoles are among the most extensively studied compounds.
These plant-derived bioactive compounds have been shown to influence DNA methylation
patterns, histone modifications, and microRNA expression, thereby altering the gene expression
allied with prostate cancer progression, cell proliferation, and apoptosis. We also explore preclinical
and clinical studies investigating the efficacy of dietary plant metabolites as standalone treatments
or in combination with traditional treatments for people with prostate cancer. The present work
highlights the potential of dietary plant metabolites as epigenetic modulators to treat prostate cancer.
Continued research in this field may pave the way for personalized and precision medicine approaches,
moving us closer to the goal of improved prostate cancer management.
Exploring the Mechanisms of Sanguinarine in the Treatment of Osteoporosis by Integrating Network Pharmacology Analysis and Deep Learning Technology
Authors: Tang Yonghong , Zhou Daoqing , Gan Fengping , Yao Zhicheng , Zeng Yuqing
Published: February 2024

Background:

Sanguinarine (SAN) has been reported to have antioxidant, antiinflammatory,
and antimicrobial activities with potential for the treatment of osteoporosis (OP).

Objective:

This work purposed to unravel the molecular mechanisms of SAN in the treatment of
OP.

Methods:

OP-related genes and SAN-related targets were predicted from public databases. Differential
expression analysis and VennDiagram were adopted to detect SAN-related targets
against OP. Protein-protein interaction (PPI) network was served for core target identification.
Molecular docking and DeepPurpose algorithm were further adopted to investigate the binding
ability between core targets and SAN. Gene pathway scoring of these targets was calculated
utilizing gene set variation analysis (GSVA). Finally, we explored the effect of SAN on the expressions
of core targets in preosteoblastic MC3T3-E1 cells.

Results:

A total of 21 candidate targets of SAN against OP were acquired. Furthermore, six core
targets were identified, among which CASP3, CTNNB1, and ERBB2 were remarkably differentially
expressed in OP and healthy individuals. The binding energies of SAN with CASP3,
CTNNB1, and ERBB2 were -6, -6.731, and -7.162 kcal/mol, respectively. Moreover, the GSVA
scores of the Wnt/calcium signaling pathway were significantly lower in OP cases than in
healthy individuals. In addition, the expression of CASP3 was positively associated with
Wnt/calcium signaling pathway. CASP3 and ERBB2 were significantly lower expressed in
SAN group than in DMSO group, whereas the expression of CTNNB1 was in contrast.

Conclusion:

CASP3, CTNNB1, and ERBB2 emerge as potential targets of SAN in OP prevention
and treatment.
Promising Pharmaceutical Compounds of Marine Fishes: Their Chemistry and Therapeutic Applications
Authors: Ramesh Santhanam , Santhanam Ramasamy , Sankar Veintramuthu
Published: February 2024

This chapter deals with the bioactive potential of the different groups of
marine fishes viz. cartilaginous, bony, and jawless fish species.
New PG Degree Course, Marine Bio-Pharmacy: Scope and Career Prospects
Authors: Ramesh Santhanam , Santhanam Ramasamy , Sankar Veintramuthu
Published: February 2024

This chapter deals with the importance and recent status of marine
biopharmaceuticals and the need for popularizing this aspect; the introduction and
scope of Marine Bio-Pharmacy as an interdisciplinary PG course; suggested syllabus
for taught program and practicals in the event of its introduction; and career
opportunities for the Marine Bio-Pharmacy graduates.
Marine Biopharmaceuticals: Scope and Prospects
Authors: Ramesh Santhanam , Santhanam Ramasamy , Sankar Veintramuthu
Published: February 2024

Marine Biopharmaceuticals: Scope and Prospects is a collaboration of experts in pharmacology, biology and biochemistry with a focus on Marine Bioprospecting. The book provides an in-depth exploration of promising pharmaceutical compounds found in various marine biota and their therapeutic applications. The comprehensive contents cover marine ecosystems, marine biopharmaceutical, and delve into the chemistry and therapeutic applications of compounds from diverse marine organisms such as seaweeds, sponges, cnidarians, bryozoans, worms, shellfish, tunicates, and fishes.

The chapters also highlight approved and marketed marine biota-derived drugs and marine biota-derived drug candidates currently under clinical trials. Marine biopharmaceutical compounds targeting SARS-CoV-2 are also covered, reflecting the latest developments in the field. The editors conclude the book by advocating for the establishment of professional grade Marine Biopharmacy courses at university level to contribute to this emerging field.

This reference serves as a guide for researchers and instructors in disciplines such as Pharmaceutical Sciences, Marine Biology, Marine Microbiology, Marine Biochemistry, and Marine Biotechnology. Moreover, it is positioned as a standard reference for libraries in colleges and universities, offering critical insights for drug companies engaged in the development of new drugs from marine biopharmaceuticals.
The Flipped-Classroom Instructional Procedure Development and Its Implementation Effectiveness in Improving Procedural Knowledge Learning Outcomes at Vocational High Schools
Authors: Herlambang Admaja Dwi , Fransisca Olivia Dyah , Afirianto Tri
Published: February 2024

The students’ number limitation in a classroom and the compression of face-to-face time challenge teachers to present practical learning scenarios to achieve learning objectives. This study aims to develop student learning procedures with the flipped classroom (FC) instructional model and determine its use in improving student learning outcomes. The research was conducted at a public information technology vocational high school in Malang, East Java Province, Indonesia. The FC instructional procedure development approach is based on the ADDIE (analysis, design, development, implementation, and evaluation) phase. The FC instructional procedure was developed in conjunction with a constructivist instructional strategy, consisting of five primary stages: (1) perception, (2) exploration, (3) restructuring, (4) implementation, and (5) review and evaluation. FC instructional procedure effectiveness was tested using the Randomized Pre-test and Post-test Control Group Design research design. The control and experimental groups consist of 30 students with randomization. The research found that the learning outcomes of the experimental group (EGLO = 70.00) were greater than those of the control group (CGLO = 64.30). The normalized gain index of the experimental groups (g = 0.50) was more significant than the control groups (g = 0.41). The conclusion is that the FC procedures with a constructivist approach have proven more effective in improving student learning outcomes.
Potential Use of ChatGPT in Responding to Patient Questions and Creating Patient Resources
Authors: Reynolds Kelly , Tejasvi Trilokraj
Published: February 2024

ChatGPT (OpenAI) is an artificial intelligence–based free natural language processing model that generates complex responses to user-generated prompts. The advent of this tool comes at a time when physician burnout is at an all-time high, which is attributed at least in part to time spent outside of the patient encounter within the electronic medical record (documenting the encounter, responding to patient messages, etc). Although ChatGPT is not specifically designed to provide medical information, it can generate preliminary responses to patients’ questions about their medical conditions and can precipitately create educational patient resources, which do inevitably require rigorous editing and fact-checking on the part of the health care provider to ensure accuracy. In this way, this assistive technology has the potential to not only enhance a physician’s efficiency and work-life balance but also enrich the patient-physician relationship and ultimately improve patient outcomes.
Digital Care Pathway for Patients With Sleep Apnea in Specialized Care: Mixed Methods Study (Preprint)
Authors: Haverinen Jari , Harju Terttu , Mikkonen Hanna , Liljamo Pia , Turpeinen Miia , Reponen Jarmo
Published: February 2024

BACKGROUND

Sleep apnea is a significant public health disorder in Finland, with a prevalence of 3.7%. Continuous positive airway pressure (CPAP) therapy is the first-line treatment for moderate or severe sleep apnea. From November 18, 2019, all patients who started their CPAP therapy at Oulu University Hospital were attached to a sleep apnea digital care pathway (SA-DCP) and were instructed on its use. Some patients still did not use the SA-DCP although they had started their CPAP therapy.

OBJECTIVE

We aimed to study health care professionals’ (HCPs’) perspectives on the SA-DCP and its usefulness for their work; whether the main targets of SA-DCP can be reached: shortening the initial guiding sessions of CPAP therapy, reducing patient calls and contact with HCPs, and improving patients’ adherence to CPAP therapy; and patients’ perspectives on the SA-DCP and its usefulness to them.

METHODS

Overall, 6 HCPs were interviewed in May and June 2021. The survey for SA-DCP users (58/91, 64%) and SA-DCP nonusers (33/91, 36%) was conducted in 2 phases: from May to August 2021 and January to June 2022. CPAP device remote monitoring data were collected from SA-DCP users (80/170, 47.1%) and SA-DCP nonusers (90/170, 52.9%) in May 2021. The registered phone call data were collected during 2019, 2020, and 2021. Feedback on the SA-DCP was collected from 446 patients between February and March 2022.

RESULTS

According to HCPs, introducing the SA-DCP had not yet significantly improved their workload and work practices, but it had brought more flexibility in some communication situations. A larger proportion of SA-DCP users familiarized themselves with prior information about CPAP therapy before the initial guiding session than nonusers (43/58, 74% vs 16/33, 49%; P=.02). Some patients still had not received prior information about CPAP therapy; therefore, most of the sessions were carried out according to their needs. According to the patient survey and remote monitoring data of CPAP devices, adherence to CPAP therapy was high for both SA-DCP users and nonusers. The number of patients’ phone calls to HCPs did not decrease during the study. SA-DCP users perceived their abilities to use information and communications technology to be better than nonusers (mean 4.2, SD 0.8 vs mean 3.2, SD 1.2; P<.001).

CONCLUSIONS

According to this study, not all the goals set for the introduction of the SA-DCP have been achieved. Despite using the SA-DCP, some patients still wanted to communicate with HCPs by phone. The most significant factors explaining the nonuse of the SA-DCP were lower digital literacy and older age of the patients. In the future, more attention should be paid to these user groups when designing and introducing upcoming digital care pathways.

CLINICALTRIAL
Exploring the effects of variety and amount of mindfulness practices on depression, anxiety, and stress symptoms: an investigation on a mental health-focused eHealth system for breast and prostate cancer patients. (Preprint)
Authors: Malandrone Francesca , Urru Sara , Berchialla Paola , Rossini Pierre Gilbert , Oliva Francesco , Bianchi Silvia , Ottaviano Manuel , Gonzalez-Martinez Sergio , Carli Vladimir , Valenza Gaetano , Scilingo Enzo Pasquale , Carletto Sara , Ostacoli Luca
Published: February 2024

UNSTRUCTURED

This study aims to investigate the impact of Internet-based Mindfulness-Based Interventions (e-MBIs) on anxiety, depression, and stress symptoms in prostate and breast cancer patients. The primary aims are to assess the association between the amount and variety of e-MBI practices and symptom reduction. Secondly, the study aims to examine how baseline information such as sociodemographic characteristics and dispositional mindfulness (DM) and dispositional self-compassion (DSC) correlate with both app usage and symptom reduction.
Data from the NEVERMIND project were used, involving 107 patients. A longitudinal design assessed Pearson’s correlation to analyse the relationship between the amount and duration of e-MBI practices. Linear regression gauged the dose-response effect, evaluating DM and DSC impact on depression, anxiety, and stress. Negative binomial regression studied sociodemographic factors' influence on e-MBI practice amount.
The participants with more diverse and sustained mindfulness practices (TP=1) experienced significant reductions in depression, anxiety, and stress. A high correlation (0.94) between e-MBI practices and symptom reduction is also highlighted. Male, married, and highly educated patients were more likely to engage in mindfulness. Even if DM and DSC did not impact the amount or variety of practices correlated, they were correlated with symptom reduction, showing that higher levels were associated with significant reductions in depression, anxiety, and stress.
While more e-MBI practice is linked to reduced anxiety, depression, and stress, the study emphasises the crucial role of variety of practice over amount. DM and DSC are key in shaping intervention effectiveness and may act as protectors against psychological distress. Using app log data, our research provides a unique perspective on e-MBI impact, contributing to cancer care understanding and guiding future studies.
#Chronicillness, Posts with Medical Content Receive More Attention on Instagram: Content Analysis (Preprint)
Authors: Daon Lindsey D. , Lee Fu-Shiuan Whitney , Saynina Olga , Wang C. Jason
Published: February 2024

BACKGROUND

Social media is an integral part of modern life in which people connect, learn, and share. The content shared on social media can drive behavior change as people, especially adolescents, seek to gain or maintain popularity. #Chronicillness is a rising trend on social media, yet the content and attention it garners remain poorly understood.

OBJECTIVE

This study aimed to analyze Instagram posts related to chronic illness by examining their content and assessing if posts with medical-related content received greater attention.

METHODS

To study individuals with chronic illness, publicly available Instagram posts were searched for hashtags related to chronic illness. We used a mixed-methods approach which included qualitative analysis of captions, hashtags, and photos for medical conditions, locations, and presence of medical equipment, alongside quantitative analysis to examine the relationship between medical content and attention. Multivariate analyses were performed to determine the odds of medical content Overperforming, a proxy measure for attention.

RESULTS

Content analysis of 279 posts revealed caption themes including Medical Experiences, Illness Journey, Connection, and Non-illness Experiences. Among the posts, 97 (35%) included medical content, 52 (19%) featured advertisements, and 10 (4%) depicted invasive medical equipment. Hashtags covered a wide range of 107 different conditions. Posts with medical content exhibited significantly higher odds of overperforming (OR 1.85; 95% CI: 1.01, 3.42), as did posts with photos containing invasive medical equipment (OR 6.19; 95% CI: 1.16, 32.99).

CONCLUSIONS

Our findings underscore the potential reinforcing effect of sharing medical information on Instagram, the inadvertent promotion of invasive medical procedures as visible signs of illness, and the possibility of adolescents mimicking this attention-generating content. It is crucial to implement strategies for fostering positive and informed interactions within online communities, and to address the potential risks associated with overmedicalization, misinformation, and the commodification of health experiences.
Diagnostic performance of artificial intelligence tools for article screening during literature review: A systematic review (Preprint)
Authors: Sucaldito Ma. Sergia Fatima , Yu Kaela Czarina
Published: February 2024

BACKGROUND

The burgeoning volume of scientific literature being generated today places a great burden on evidence reviewers. On average, only 2% to 8% of articles yielded by a search strategy are ultimately included in a systematic review. Due to the burden of increasing information loads, there is a demand for methods that improve efficiency while maintaining accuracy in performing evidence reviews.

OBJECTIVE

This systematic review aims to determine the accuracy and efficiency of AI-assisted abstract selection compared to manual abstract selection, as assessed by diagnostic performance and workload saved over sampling (WSS).

METHODS

Two reviewers searched PubMed, Proquest, and Cochrane Library for studies evaluating the diagnostic performance and/or workload savings achieved by any AI tool, whether through full or semi-automation, in the title and abstract screening phase of literature review. Variance-weighted random effects meta-analysis was done to generate univariate measures of sensitivity, specificity, and WSS for the studies using RevMan verson 4.3 and the ‘meta’ and ‘mada’ packages on R version 4.3.1. Bivariate analysis was also performed for the measures of diagnostic accuracy and a hierarchal summary operating characteristics curve (HSROC) was generated.

RESULTS

Twenty-two studies were included in this review, where 13 reported diagnostic performance, 14 reported WSS, and five studies reported both outcomes. In fully automated workflows, AI tools had a sensitivity of 85.6% (95% CI: 60.8%-95.8%) and a specificity of 88.7% (95% CI: 58.7%-97.7%) with considerable heterogeneity, which likely stems from the differences in the SRs and AI techniques used. In semi-automated workflows, sensitivity was 87.6% (95% CI: 77.2%-93.6%) and specificity was 94.1% (95% CI: 60.0%-99.4%) also with considerable heterogeneity. Among studies on full automation, the median workload savings for 100% recall was 50.0% (IQR: 10.2), while for studies on semi-automation, the median workload savings was 55.6% (IQR: 16.4).

CONCLUSIONS

Given the findings of this review, the diagnostic performance of AI tools appeared to be superior when used in semi-automated workflows rather than fully automated ones. This suggest that AI tools hold great potential in augmenting the accuracy and efficiency of human reviewers during study selection in literature review.
A Deep Learning Model for Predicting User Personality Using Social Media
Authors: Shaikh Misfer
Published: February 2024

Abstract: Social media is a form of communication based on the internet to share information through content and images. Their choice of profile images and type of image they post can be closely connected to their personality. The user posted images are designated as personality traits. The objective of this study is to predict five factor model personality dimensions from profile images by using deep learning and neural networks. Developed a deep learning framework-based neural network for personality prediction. The personality types of the Big Five Factor model can be quantified from user profile images. To measure the effectiveness, proposed two models using convolution Neural Networks to classify each personality of the user. Done performance analysis among two different models for efficiently predict personality traits from profile image. It was found that VGG-69 CNN models are best performing models for producing the classification accuracy of 91% to predict user personality traits. Keywords Personality Traits, Classification, Deep Learning, Convolution Neural Networks, Five Factor Model
Apakah Karakter Eksekutif Memoderasi Hubungan Antara Thin Capitalization, Transfer Pricing, Financial Distress dan Penghindaran Pajak?
Authors: Rohmah Vina Auliyaur , Romadhon Fitri
Published: February 2024

Purpose: This research is used to examine the effect of thin capitalization, transfer pricing, and financial distress on tax avoidance with executive character as a moderating variable in hotel, restaurant, and tourism service companies listed on the Indonesia Stock Exchange for the 2017-2019 period.
Methodology/approach: The population of this research is 38 companies. Based on the purposive sampling method, the sample in this research was 18 companies. The data analysis method used in this research is the panel data regression analysis method and the data is processed using Eviews software
Findings: The results showed that thin capitalization and financial distress had an effect on tax avoidance, while transfer pricing had no effect. The executive character is able to moderate the effect of thin capitalization and transfer pricing on tax avoidance but is unable to moderate the effect of financial distress on tax avoidance.
Practical and Theoretical contribution/Originality: This research has important implications for several parties, one of which is for regulators, namely the results of this study indicate that tax regulations need to be tightened so that opportunities or loopholes for tax avoidance can be minimized.
Research Limitation: This research is limited to service companies, especially in the hotel, restaurant, and tourism sectors. Besides that, the executive characteristic variable in this study was only measured in relation to the executives' risk preferences in decision making.
Aplikasi Kasir Moka Pos Dan Kinerja Karyawan: Efek Moderasi Kepuasan Pelanggan
Authors: Wulandari  , Mappadang Agoestina
Published: February 2024

Purpose: One of the best cashier applications currently in Indonesia that is widely used is Moka Pos. This study is to determine whether the elffelctivelnelss of ulsing the Moka Pos application has a positive and significant effect on employee performance at thel ONNI Houlsel relstaulrant, and whether customer satisfaction can modelratel thel rellationship beltweleln thel elffelctivelnelss of Moka Pos and elmployelel performance.
Methodology: Thel population in this stuldy were 30 visitors who camel to thel ONNI Houlsel relstaulrant, with 30 peloplel taking thel samplel. Thel analytical melthod ulseld is mulltiplel relgrelssion analysis melthod.
Findings: Baseld on thel relsullts of thel stuldy it can bel obtaineld that thel variablel Elffelctivelnelss of ulsing thel MOKA Post application (X1), has an elffelct on thel Elmployelel Pelrformancel variablel (Y) at thel ONNI Houlsel relstaulrant, and thel Culstomelr Satisfaction variablel (Z) modelratels thel rellationship beltweleln thel elffelctivelnelss of Moka Pos and elmployelel pelrformancel.
Practical & Theoritical contribution:  This study contributions to behavioral accounting and practically reduces cashless and increase revenue.
Research Limitation: This study was limited to the population at one company.
Modal Manusia Memoderasi Pengaruh Kapabilitas Financial Pada Kinerja UKM
Authors: Sulistyowati Rina , Nataliawati Rita , Winarsih Tri , Nabila Silfa Syabilatul , Sari Diana Septiya
Published: February 2024

Purpose: This study is to determine the performance improvement of SMEs in Surowiti Gresik Village through financial capability with human capital as a moderating variable
Methodology/approach: The sample determination method used is total sampling with 85 respondents. Questionnaires were used in data collection. The data analysis method used in this study was Structural Equations Modeling with PLS 3.2.7.
Findings: The results of the study prove that financial capabilities affect the performance of SMEs and human capital is able to moderate the effect of financial capabilities on the performance of SMEs
Practical and Theoretical contribution/Originality: SMEs in Surowiti village need to be aware of the importance of financial capabilities in managing their business so that their business can develop well. It is hoped that this research will be able to contribute as a reference for managing SMEs with good financial knowledge and of course human capital that supports and wants to develop
Research Limitation: The results of this research are limited to the SME sector in Surowiti Gresik Village. In the future, research can develop this research by adding SME industries in other villages to expand indicators of financial capability and human capital.
Evaluasi Atas Implementasi Pernyataan Standar Akuntansi Pemerintahan Nomor 13 Pada BLUD Puskesmas Kawasan Terpencil
Authors: Lelono Wijoseno , Siswantoro Dodik
Published: February 2024

Purpose: This study aims to evaluate the suitability of accounting and presentation of BLUD Puskesmas Financial Statements with the Statement of Government Accounting Standards Number 13, and identify the role of financial guidance carried out by the Health Office and the Regional Financial Management Officer (PPKD).
Methodology/approach: This research was conducted at BLUD Puskesmas X, with a qualitative method through a case study approach. The data collection methods adopted in this study include document analysis and interviews
Findings: The results showed that the condition of the presentation of the Financial Statements of BLUD Puskesmas X was not fully in accordance with PSAP 13, and the implementation of accounting was not fully in accordance with SE Director General of Bina Keuda No. 981/4092/KEUD, namely without making journals, posting to the General Ledger, and preparing the Balance Sheet. In terms of guidance, the Health Office has provided various coaching activities related to the preparation of Financial Statements, while PPKD               has not provided intensive guidance and is more directed at reconciling financial data between BPKAD and BLUD Puskesmas X.
Practical and Theoretical contribution/Originality: This research is expected to provide suggestions and insights for BLUD Puskesmas management regarding aspects of the Financial Statement preparation process that require improvement, as well as contributing information for further research related to the development of Accounting, especially the implementation of Public Sector Accounting Standards
Research Limitation: The interview process was conducted via online media and telephone due to geographical location considerations, namely BLUD Puskesmas X is located relatively far from the capital city of District AAA, about 295 KM with inland road access conditions on Borneo Island.
The Influence of Understanding Regulations, Internship and Socialization on The Implementation of Supertax Deduction Incentives
Authors: Machfuzhoh Asih , Muttaqin Galih Fajar
Published: February 2024

Purpose: This research aims to test the influence of understanding supertax deduction incentive regulations, vocational student internships, and socialization of supertax deduction incentives, on the implementation of supertax deduction among Vocational Program Partners at UNIRTA
Methodology/approach: The sample for this research was all industry partners involved in the FEB Untirta Diploma Three internship program in 78 industries spread across Banten Province. The research methodology stage begins with collecting data through distributing questionnaires to vocational partners, followed by data analysis. This research data is primary, the data was analyzed using validity and reliability tests and multiple linear regression tests.
Findings: The results of this research found that the influence of understanding supertax deduction incentive regulations, vocational student internships, and socialization of supertax deduction incentives had an influence on the implementation of supertax deduction.
Practical and Theoretical Contribution/Originality: This research contributes to the reader with the novelty of variables and theories used by researchers, thus adding broader insight.
Practical and Theoretical contribution/Originality: This research contributes to the reader with the novelty of variables and theories used by researchers, thus adding broader insight.
Research Limitation: This research only examined vocational partners at one university.
Does off-farm employment affect farmers’ adoption of green control techniques?
Authors: Yu Lili , Wang Yaqi , Xie Hongling , Yao Xue , Liu Bei
Published: February 2024

Actively encouraging farmers to adopt green control techniques (GCT) is an important measure for achieving sustainable agricultural development and ensuring global food security. Based on microsurvey data covering 912 households in Henan and Shandong Provinces, this paper uses a binary probit model to explore the effect of off-farm employment on the adoption behavior of farmers’ GCT and the mechanism of the effect. The study finds that off-farm employment has a capacity accumulation (CAP) effect and a crowding-out (CROWD) effect on farmers’ GCT adoption behavior. Additionally, the CROWD effect generally exceeds the CAP effect, making off-farm employment unfavorable for farmers’ adoption of GCT. Further analysis finds that off-farm employment has a positive effect on the adoption of GCT by farmers based on agricultural income, and as the distance from off-farm employment increases, the positive effect is greater. In contrast, off-farm employment has a negative effect on rural households whose main income is nonagricultural income, and with the increase in the distance from off-farm employment, its negative effect gradually increases. On this basis, to promote green prevention and control techniques for diseases and insect pests, we should focus on farmers whose main income is agricultural, enhance their CAP effect, and guide farmers whose main income is nonagricultural to transfer out of their land. While enriching research on GCT, this paper also provides an empirical basis and policy reference for how to better promote GCT during the period of rapid development of off-farm employment.
Tacit Choice of Law in the Metaverse: What Law Applies?
Authors: Meliala Aurora Jillena , Putra Akbar Kurnia
Published: February 2024

This research discusses the reality of the metaverse with emphasis placed on the need for a rule of law for certain activities within it that is related to Private International Law. This research observes what the metaverse is, its prevalent structure and the recent dialectics on the place of international law as a comprehensive and much needed legal regime within its system. This article utilises a normative legal research methodology and uses qualitative data such as legal theories and related research to arrives at a certain conclusion on the place of Private International Law in the Metaverse. The first part of this research elaborates on the relationship between the Metaverse and Law and the importance of a clear rule of law in the Metaverse. The second part provides an overview of Private International Law in regards to the notions that exist within it to determine a prescriptive jurisdiction. The third section discusses tacit choice of law as an alternative answer to the current uncertainty in the commercial world of the Metaverse. While the last part talks about the incorporation of metaverse regulations in the domestic and regional scenes. The  article finds that the need for a clear legal framework not only in regards to choice of law but also for all aspects of the Metaverse is direly needed. While tacit choice can provide legal certainty in the world of commercial contracts, a comprehensive cybersecurity regime is needed for a Metaverse that is truly based in rule of law.
The Influence of Leadership, Organizational Commitment, and Work Environment on Employee Performance
Authors: Ismansyah Defrino , Parwoto Parwoto
Published: February 2024

This study aims to determine the effect of leadership, organizational commitment and work environment on employee performance at PT Sugity Creatives Indonesia. The research method is associative research, with data collection through a questionnaire, literature study and interviews. Testing was carried out with a sample of 64 people using the purposive sampling method, measurement scales using Likert scale. On the analysis of data using multiple linear regression test with SPSS 26 program.Testing of partial variable results that showed leadership affected the employee performance with a level of significance of 0.007 < 0.05. organizational commitment has no effect on employee performance with a level of significance of 0.110> 0.05, and work environment affects employee performance with a level of significance of 0.032< 0.05. Therefore, it needs to be a serious concern for leaders in PT Sugity Creatives Indonesia affecting the performance of the employees, of some of the indicators that the author described based on a detailed questionnaire results are expected to increasingly see the performance of employees in PT Sugity Creatives Indonesia.
The Positioning of Coffee Shops Based on Consumer Perceptions: Study of Coffee Shops in Brebes Regency
Authors: Aziz Muhamad Syahrul , Iskandar Khalid , Ikhwan Syariefful
Published: February 2024

The coffee shops are starting to bloom in Indonesia and are attracting more and more coffee lovers. Coffee shop growth rates also occur in Brebes Regency. Many new coffee shop brands offer new facilities and concepts to the community, especially the Brebes Regency area, so that every coffee shop entrepreneur must know the positioning in order to survive in the competition. The purpose of this study was to determine the mapping of consumer perceptions of the 3 coffee shops included in the research object in Brebes Regency, namely Kelirumology Coffee, Rajaswa Coffee and Warkop 12 based on the attributes of service quality, brand, location, facilities, price, menu diversity, and atmosphere so that useful to know the positioning of the coffee shop. Positioning is determined by reading the perceptual maps generated based on multidimensional scaling (MDS) analysis. The research data were obtained from questionnaires, library research, and direct observation according to the research objectives. The analysis technique uses multidimensional scaling with a sample of 86 respondents from consumers who have visited the 3 coffee shops. The results showed that consumers have their own perception of each brand based on the attributes of service quality, brand, location, facilities, price, menu variety and atmosphere. On the perception map, the coffee shop brand Kelirumologi Kopi leads because it is in quadrant I with positive coordinates in each dimension. Coffee shop brand Warkop 12 is in quadrant III. The Rajaswa Coffee brand is in quadrant IV. The results of the Kelirumologi Coffee coffee shop mapping lead with superior menu diversity, prices and facilities. But Kelirumologi Kopi has a weakness in brand attributes. Rajaswa Coffee coffee shop ranks second with excellence in brand and location attributes. But Rajaswa Coffee has weaknesses in the attributes of service quality and menu variety. Coffee shop Warkop 12 last place with excellence in service quality and atmosphere. And Warkop 12 has weaknesses in the attributes of location and price.
Subliminal Throwback complete documentation
Authors: Natasha Barrett
Published: February 2024

Subliminal Throwback was a site-specific outdoor 3-D audio sound installation located in the amphitheatre between Gydas vei 8 and Slemdalsveiein 11 at Majorstuen, Oslo. The work was created by Natasha Barrett as part of the Reconfiguring the Landscape Project hosted by the Norwegian Academy for Music in Oslo.

Subliminal Throwback marked the end of a year-long process researching and experimenting on this urban outdoor sound landscape, and includes the application of innovative technical and artistic approaches to investigating its potentially interesting qualities - acoustic features, sounds that pass us by, or qualities too fleeting to pay heed to amidst our other thoughts and activities.
Reconfiguring the Landscape
Authors: Natasha Barrett
Published: February 2024

Reconfiguring the Landscape was a Norwegian artistic research project hosted at the Norwegian Academy for Music and funded by the Norwegian Agency for International Cooperation and Quality Enhancement in Higher Education (DIKU). The project investigated how 3-D electroacoustic composition and sound-art can evoke and provoke a new awareness of our outdoor environment. The work addressed both urban and natural settings. The project was led by Natasha Barrett and included an international lineup of composers, technologists and scientists who contributed in different ways. The project startup was in November 2019, just a few months before COVID impacted all activities. From 2020-2021 the project members worked independently. In 2022 group activities resumed. Research work formally ended in the beginning of 2023, and public dissemination and documentation concluded in November 2023.
Linha de Cuidado de Artrodese de Coluna Pediátrica: reduzindo custos de diárias de UTI SUS
Authors: Pasquini Netto Harli , Neves Kharol , Miyake Okumura Lucas , Roseira Allana , Ferreira Matos Roseli , Muller Avilla Luiz , Erdmann Bini Cordeiro Luca , Cavadas da Costa Soares Leonardo , Campos Ricieri Marinei , De Araújo Motta Fabio
Published: February 2024

Objetivo: Avaliar a minimização de custos relacionados ao tempo de internação em Uni-dade de Terapia Intensiva (UTI), após implementação de uma Linha de Cuidado (LC) de Artrodese de Coluna. Método: Análise de minimização de custos que considerou dados administrativos da LC de um hospital pediátrico. Foram considerados dois períodos de análise: pré (2019) e pós-implementação completa da LC (2022), na perspectiva do SUS como fonte pagadora. O custo da diária em UTI foi baseado em tabela SIGTAP. Análise de impacto orçamentário com horizonte temporal de 5 anos foi realizada para estimar a economia gerada pelo maior número de pacientes que recebem a LC ao longo dos anos. Resultados: 64 pacientes foram acompanhados pela LC em 2019 (tempo médio; TUTI: 3,8 dias) e 62 pacientes (tempo médio; TUTI: 0,8 dias) em 2022, sugerindo uma redução média de 3 dias de UTI, e acarretando em uma minimização de custos de R$189 mil, para 60 pacientes acumulados em 5 anos. Além disso, foi observado menor tempo de hospitalização total. Conclusão: A implementação da estratégia de Linha de Cuidado de Artrodese de Coluna é considerada efetiva sob o ponto de vista de promover alta hospitalar aos pacientes. Otimiza o tempo de UTI, sugerindo uma melhor capacidade de alocação eficiente de recursos no SUS.
Multi-criteria home energy management system selection for the smart grid support
Authors: Janjic Aleksandar , Velimirovic Lazar , Velimirovic Jelena
Published: February 2024

Home energy management systems (HEMS) are increasingly used as a tool that creates optimal consumption and production schedules for Smart Grids, by considering objectives such as energy costs, environmental concerns, load profiles, and consumer comfort. Multiple criteria selection of optimal HEMS seems to be superior to the traditional cost benefit assessment in measuring intangibles and soft impacts, introducing qualitative aspects in the analysis. This paper proposes an algorithm for the selection of optimal HEMS, using the fuzzy AHP method. This methodological framework provides a multi-criteria approach for estimating the benefits and costs of different HEMS within the Smart Grid uncertain environment. This method allows the decision makers to incorporate unquantifiable, asymmetrical, incomplete, nonobtainable information and partially ignorant facts into a decision model. Four criteria and eleven performances for the optimal solution selection are defined. The method is successful in the evaluation of alternatives in the presence of heterogeneous criteria and uncertain environment. The methodology is illustrated on the choice of HEMS from the power distribution company perspective. It is concluded that the evaluation of weighting factors has a decisive character in the choice of the final one of several alternative variants. Fuzzification of input values can also contribute to a more flexible view of the given problem and analysis of sensitivity to various input parameters.
Efficiency of physical-chemical treatment of wastewater of the paper and cardboard factory
Authors: Sablii Larysa , Obodovych Oleksandr , Sydorenko Vitalii
Published: February 2024

The purpose of the work is to study the wastewater treatment of a cardboard and paper factory in the Khmelnytskyi region using physico-chemical methods, namely coagulation and oxidation, to increase the efficiency of removing organic pollutants according to COD and BOD indicators. The use of coagulation and chlorination methods, before biological treatment in aeration tanks, was proposed. Alumofloc 18% was used as a coagulant, PAA was used as a flocculant, and sodium hydroxide was used as an alkalizing reagent. The study was conducted on a mixture of industrial and sewage wastewater with COD and BOD5 ? 3200 and 1575 mg L?1, respectively, and on industrial wastewater with COD and BOD5 ? 4480 and 1960 mg L?1, respectively. The effects of reducing COD and BOD5 indicators in the first case after coagulation were 30 and 40%, after chlorination ? 37.82 and 43.18%, respectively, and in the second after coagulation ? 28.58 and 47.25%, respectively. The effects of wastewater treatment of a cardboard and paper factory using coagulation and oxidation methods will allow for a reduction in the concentration of organic substances according to COD and BOD indicators before the biological treatment of wastewater in aeration tanks and also will ensure an increase in the efficiency of biological treatment.
Perception of the Contribution of Video Demonstrations in Dental Practical Training
Authors: El Assraoui Khadija , Al jalil Zineb , Cheikh Yasmina , Kaoun Khadija , Chaouir Souad , Bellemkhannate Samira
Published: February 2024

Objectives: Information and communication technologies (ICT) have become integral part of our our students’ daily lives. Their use in practical teaching facilitates the learning process. With the occurrence of the COVID-19 pandemic, demonstration videos were integrated into the pre-clinical practical activities. This work aims to evaluate the students’ appreciation of the demonstration videos made for the pre-clinical practical activities (PPA) of the removable partial denture for the students of the 5th semester.Methods: The Removable Prosthodontics Department professors produced 10-minute didactic video recordings describing the themes of the pre-clinical practice activities. A descriptive cross-sectional study was conducted during the 2021–2022 academic year to assess students’ perceptions of the effectiveness and relevance of these videos. Data were collected using an anonymous questionnaire given to student volunteers at the end of the third year (June 2022).Results: The majority of students favorably appreciated the role of videos in saving time during the session, reducing stress, and better understanding of practical gestures, as well as the average length of videos, the quality of videos in terms of sound, magnification, and the usefulness of text annotations.Conclusion: Videos allow students to preview the practical gestures severaltimes before the PPA session to better see the demonstration with sufficient magnification and to reduce stress. Both techniques have proven to be effective, and their combination will bring better satisfaction to the students.