bluuebunny/crossref_metadata_2025 huggingface dataset:
5237 Sayılı Türk Ceza Kanunu'nda Kısırlaştırma Suçu
Authors: ERTUĞRUL Hüseyin
Published: June 2018

Bir
insanın üreme ve neslini devam ettirebilme hakkı, onun yaşama hakkı kadar temel
bir hakkıdır. Çünkü üreme hakkına sahip kişilerin neslini devam
ettirebilmesiyle, ancak insanlar yaşama hakkına sahip olabileceklerdir. Başka
bir ifadeyle, üreme hakkının kullanılamamasıyla neslin devamı
sağlanamayacağından, yaşama hakkı da işlevsiz hale gelecektir. Bu
mülahazalarla, ceza kanunlarında üreme hakkını korumaya yönelik kısırlaştırma
suçları düzenlenmektedir.

5237
sayılı Türk Ceza Kanunu’nun 101. maddesinde düzenlenen kısırlaştırma suçu,
üreme hakkını teminat altına almakla birlikte, öğretide bu düzenlemenin yetersiz
kaldığı da ifade edilmektedir. Bu suç tanımına, gerek hadımlaştırmanın eklenmesi
gerektiği; gerekse de, suçun kanuni tanımın kanun tekniğine uygun olmadığı
yönünde eleştiriler getirilmektedir. Bununla birlikte, 2827 sayılı Nüfus Planlaması
Hakkında Kanun’da her ergin kişiye kısırlaşma hakkı tanınmaktadır. İşte bu
hakkın korunması için, kişinin rızasız kısırlaştırılması veya rızası bulunsa
dahi, yetkisiz kişilerle bu fiilin işlenmesi durumu, Türk Ceza Kanunu’nda
kısırlaştırma suçu olarak düzenlenmiştir.
The Moderating Roles on the Relation between Internet Addiction and Burnout
Authors: Özdemir Halil Özcan , Arslan Hüsnüye Neşe
Published: June 2018

ABSTRACT

The aim of the present study is to explore the moderating role of gender
and level of education on the relation between internet addiction and burnout
of future leaders studying at the university level. The data was conveniently
collected from 233 students enrolled in the Business and Administration
Department in the Faculty of Economics and Administrative Sciences and the
Vocational School of Social Sciences in a Turkish university. The instruments
of the study were the originally named “Skala zur Erfassung der Internetsucht”
internet addiction questionnaire designed by Hahn and Jerusalem (2001) and translated
into Turkish by Şahin and Korkmaz (2011), and the Maslach Burnout Inventory –
Student Survey (MBI-SS) designed by Schaufeli et al. (2002) and translated into
Turkish by Çapri, Gündüz and Gökçakan (2011). The results of the study revealed
a positive and significant relationship between internet addiction and burnout.
However, the variables of gender and educational level were found to have no
moderating role in the correlation.
ANTIGUIDADE TARDIA: IMAGEM E DOCUMENTO
Authors: Carlan Claudio Umpierre
Published: June 2018

O artigo começa com uma descrição da iconografia como documento histórico. A imagem na Antiguidade tinha uma função específica: apresentar a um determinado grupo social, maioria analfabeto, algo que representasse a orla do poder. Ela não apenas legitimava um imperador ou rei, funcionava como uma espécie de propaganda política.
THE RESTORATION OF PERIKLES’ ODEION AT ATHENS IN THE FIRST CENTURY BC: NEW AND ANCIENT BARBARIANS
Authors: Morales Fabio Augusto
Published: June 2018

This paper discusses the restoration project of the Odeion of Perikles at Athens, carried by the Cappadocian king Ariobarzanes II sometime between 63 and 52 BC, after its partial destruction during the Sullan sack of 86 BC. This sack occurred as a punishment for the alliance between Athens and the Pontic king Mithridates VI in his war against Rome. In that context, the restoration project of this fifth century B.C. covered-theatre was meaningful for the formation of diplomatic links and networks between Athens, Rome and Cappadocia, in particular considering the complexity of the antibarbarian narratives involved. From the viewpoint of the Athenian urban history, the restoration project is an eloquent example of a new attitude towards the urban space which would become a central feature in the social production of Athenian space throughout the first century B.C.: the antiquarian urbanism.
Pedro Paulo A. Funari and Anphorology
Authors: Sarian Haiganuch
Published: June 2018

Special Issue in honour to Professor Pedro Paulo Funari
Pedro Paulo Abreu Funari e o estudo da Antiguidade
Authors: Benoit Hector
Published: June 2018

Homenagem ao Professor Pedro Paulo Abreu Funari
Nota em homenagem ao professor Pedro Paulo A. Funari
Authors: Oliveira Julio Cesar Magalhaes de
Published: June 2018

Homenagem a Pedro Paulo Abreu Funari
Homoerotismo e performances: as representações dos corpos e das relações humanas na antiguidade romana a partir das pinturas de Pompeia
Authors: Sanfelice Pérola de Paula
Published: June 2018

Os estudos da antiguidade, dentre as disciplinas acadêmicas, são aqueles considerados como o mais conservador, no entanto, por meio da interdisciplinaridade, sobretudo a partir do diálogo com a Arqueologia, esta área de conhecimento tem conseguido alcançar perspectivas mais críticas, sobretudo, em pesquisas sobre o amor e a sexualidade. Nesse trabalho, dialogo, em grande parte, com as pesquisas produzidas pelo classicista Pedro Paulo Funari, que, por sua vez, inspirou diversos pesquisadores brasileiros a romper com os modelos normativos, questionando antigos conceitos e valores patriarcais a fim de trazer à tona uma antiguidade clássica mais libertária. Deste modo, apresento algumas discussões a respeito da sexualidade e do gênero na Antiguidade romana, incialmente, um debate de natureza teórica, e, num segundo momento trago algumas pinturas de relações eróticas com práticas diversificadas, com ênfase particular às relações homoeróticas, encontradas em uma terma suburbana do sítio arqueológico de Pompeia, a fim de evidenciar as diferentes maneiras que os indivíduos interpelavam as normas, bem como questionar as noções de pornográfico e trabalhar as relações das imagens com os seus contextos.
A noção de fé verdadeira na obra poética de Prudêncio: uma análise do poema Apotheosis
Authors: Gonçalves Ana Teresa Marques
Published: June 2018

Num momento em que se buscava a consolidação dos princípios cristãos, levando os convertidos a terem práticas sociais próprias e diferenciadas das exercidas pelos gentios, Prudêncio oferece uma obra, denominada Apotheosis, na qual defende uma unicidade identitária para os cristãos, o que os faria identificar os erros das crenças indicadas como heréticas. Apresentando de forma poética os principais desvios na fé, o autor busca fornecer uma noção de fé verdadeira na qual os conversos poderiam se pautar para desenvolver as condutas corretas para aqueles que queriam seguir o Cristianismo e obter uma vida eterna após a morte. Trata-se de uma obra proselitista, que buscava fornecer cânones de exercício da fé cristã para os já convertidos e para os gentios em vias de conversão.
When the "tenth muse" inspires rap musica and drums: from the political uses of Sappo's figure by lesbians and feminist voices in contemporary Brazil
Authors: Rodrigues Leite Lettícia Batista
Published: June 2018

The object of this article is to draw attention to a dimension of the reception of the memories around the poet Sappho and the Island of Lesbos: that represented by the political uses made by militants and feminists groups and, above all, lesbian-feminist groups. Through the presentation and commentary of two examples currently found in Brazil, that I intend to draw attention to the relevance of the analysis of this type of reception.
Pedro Paulo Abreu Funari e a transmissão do conhecimento
Authors: Díaz-Andreu Margarita
Published: June 2018

Homenagem a Pedro Paulo Abreu Funari
Moldando o futuro com representações do passado em constante evolução
Authors: Silberman Neil Asher
Published: June 2018

Homenagem a Pedro Paulo Abreu Funari
O que aprendi com o professor Pedro Paulo Funari
Authors: Selvatici Monica
Published: June 2018

Homenagem a Pedro Paulo Abreu Funari
Arqueologia da generosidade
Authors: De Azevedo Katia Teonia Costa
Published: June 2018

Homenagem a Pedro Paulo Abreu Funari
Power in Ptolemaic Egypt: a magical-religious approach to legitimacy
Authors: Gralha Julio
Published: June 2018

Special issue in honour to Professor Pedro Paulo Abreu Funari
Erotic mirrors. Eroticism in the mirror. An iconography of love in ancient Greece (fifth to fourth century B.C.)
Authors: Cerqueira Fábio Vergara
Published: June 2018

This text consists of an interpretive essay about the meaning(s) of the “mirror” as an object in Mainland and Aegean Greece (in contrast to Western/Colonial Greece), based on iconography. I take into consideration two distinct repertoires of images: the paintings of Attic vases (late sixth – early fourth century B.C.) and the figurative decoration on the mirrors themselves, in relief or engraved (late fifth – early third century B.C.). The central focus of the analysis is the iconography registered on mirrors produced in the four main manufacturing centers of Greece (Athens, Corinth, Chalcis, Ionia). Greeks produced three types of mirrors between Late Archaic and Early Hellenistic times: hand-mirrors with handle, table mirrors with stand, and round box mirrors, the latter being the most important to this study. Box mirrors may bear iconography on their folding cover, in relief on the external surface (repoussé) or engraved on the interior surface. In contrast to the iconography of the vases of Magna Graecia, in which the mystic component stands out from the other symbolic aspects, in the case of the iconography of Greek mirrors erotic symbolism and the relation with the goddess Aphrodite predominate. This goddess protects all categories of women (hetaerae and "citizen-women", married or brides) and all modalities of eroticism. Under the auspices of love and desire, the symbolic power of the mirror can be related to an inclusive eroticism, which unites, that which society separates.
“Is it possible to control the crowd?” Libanius in defense of Julian and against the population of Antioch in the 4th century
Authors: Da Silva Gilvan Ventura
Published: June 2018

Regarding the recourse to humor and mockery as response mechanisms of a city’s population to the performance of imperial power, an emblematic case of estrangement between a ruler and his subjects occurred in 362-363 during Emperor Julian’s stay in the city of Antioch. Their estrangement was so intense that it led to the writing of an at least disconcerting work such as the Misopogon, a satirical text in which Julian harshly criticizes the modus vivendi of Antioch’s inhabitants. As a result of this episode, two discourses written by Libanius, To Antiochians, on the Emperor’s anger (Oration 16), and The embassy to Julian (Oration 15), attempt to reverse Antioch’s difficult situation in face of Julian’s anger. This article explores Libanius’ reasoning about the controversy involving Julian and Antioch’s inhabitants, in order to demonstrate how the sophist was committed to the emperor’s proposal of reforming the polis.
“É possível controlar a multidão?” Libânio em defesa de Juliano e contra a população de Antioquia (séc. IV)
Authors: Da Silva Gilvan Ventura
Published: June 2018

Quando tratamos do emprego do humor e do deboche como mecanismos de resposta da população urbana ao desempenho das autoridades romanas, um caso emblemático de estranhamento entre súditos e imperador é aquele que ocorre entre 362 e 363, em Antioquia, durante a estadia de Juliano na cidade.  Esse estranhamento foi tão intenso que acarretou, num primeiro momento, a elaboração de uma obra no mínimo desconcertante como o Misopógon, texto satírico no qual Juliano tece duras críticas ao modus vivendi dos habitantes da cidade.  Na sequência, como desdobramento do episódio, vem à luz dois discursos de Libânio, um deles intitulado Aos antioquenos, sobre a ira do imperador (Or. XVI) e o outro, Embaixada a Juliano (Or. XV).  Ambos os discursos buscavam reverter a difícil situação na qual se encontrava Antioquia, alvo da cólera do soberano.  Nesse artigo, pretendemos explorar os argumentos de Libânio sobre a controvérsia envolvendo Juliano e os antioquenos a fim de demonstrar como o sofista se encontrava comprometido com a proposta de reforma da pólis idealizada pelo imperador.
Vida e morte no mundo antigo: a tetrarquia e a última perseguição aos cristãos (303 – 311).
Authors: Carlan Cláudio Umpierre
Published: June 2018

O artigo começa com uma descrição do mundo romano após a Tetrarquia, com a luta pelo poder entre Constantino e, mais tarde, Licínio. Analisamos as questões políticas relativas ao mundo romano durante o período. Usando como fonte iconográfica a coleção numismática do acervo do Museu Histórico Nacional / RJ, utilizamos a imagem como uma fonte de propaganda, legitimando o poder imperial.
Late North-African sigillata lamps: curatorship of museum collections and archaeological research
Authors: Fleming Maria Isabel D’Agostino
Published: June 2018

The Late African North African lamps of Terra Sigillata (African Red Slip Ware-ARS) are a category of objects which, alongside tableware, have acquired particular importance, not only for the volume of their production, but for their economic and commercial, iconographic and historical-religious implications. This article aims to present the development of fundamental research for the knowledge about the production and circulation of the ARS and in particular the lamps, taking as examples rich dialogues between the curatorial studies of museological collections and archaeological research that point the limits of the classical models of study of African ceramics and perform accurate reviews of dates, origins and contents of vessels, especially with archaeometric methods.
Vinho: um patrimônio cultural da humanidade
Authors: Cavicchioli Marina Regis
Published: June 2018

Os processos de identificação cultural nos fazem escolher aquilo que queremos como memória, como identidade com o passado, aquilo que queremos preservar. Para tanto, como projetos identitários coletivos elegem-se os patrimônios. As últimas três décadas foram marcadas por um crescente debate em torno da questão da valorização dos diversos tipos de patrimônio cultural. Neste contexto, o vinho, através dos vinhedos e da paisagem que este constrói, das arquiteturas e dos monumentos ligados à ele, bem como suas formas de produção e consumo, coloca-se, através da proteção da UNESCO, como um patrimônio mundial.
Wine: a cultural world heritage
Authors: Cavicchioli Marina Regis
Published: June 2018

The processes of cultural identification make us choose what we want as memory, what we identity with in the past, and what we want to preserve. This is how we select our cultural heritage projects: as collective identity projects. The last three decades have been marked by a growing debate around the question of valuating the various types of cultural heritage. In this context, wine is considered as a world heritage phenomenon—through the vineyards and the landscape its production creates, the architecture and monuments linked to it, and its forms of production and consumption, through UNESCO's protection.
Objetividade e subjetividade na historiografia
Authors: Funari Pedro Paulo Abreu
Published: June 2018

Objetividade e subjetividade na historiografia
Introduction
Authors: Weiß Andreas
Published: June 2018

In the nineteenth century, transmitting knowledge of the world became
one of the most important tasks for education. As the last blank spots
on the map were filled in, geographical knowledge assumed particular
importance. In order to do business, assess political situations, and make
travel plans, young adults had to learn more than etiquette, manners,
religion and history. This knowledge of the world was conveyed to minors
primarily via pedagogical instruction (for example, by way of geography
textbooks), but also via adventure stories and travel novels.
Are “the Natives” Educable?
Authors: Wesseling Elisabeth , Dane Jacques
Published: June 2018

This article explores how geography textbooks and missionary stories
were used to persuade Dutch primary schoolchildren of the moral righteousness of
the Ethical Policy for the Dutch East Indies between 1890 and 1910. Educative discourses
targeting Dutch children were instrumentalized in order to recruit the next
generation of missionaries, colonial administrators, and overseas entrepreneurs. To
achieve this aim, they dwelt at length on the opportunities for and constraints on
uplifting indigenous children in the Indies. These narratives all convey the message
that Indies children, though certainly capable of improvement, would never attain
the same level of civilization and moral integrity as their Dutch counterparts.
Morphological and anatomical studies of the newly recorded Rhus chinensis Mill. (Anacardiaceae) from Turkey
Authors: Eminagaoglu Özgür , Ozcan Melahat
Published: June 2018

Rhus chinensis Mill. (Anacardiaceae) has been reported as a new record for the flora of Turkey. Detailed morphological description and leaf anatomical properties are provided. Capitate glandular and nonglandular trichomes, and also epicuticle hairs have been observed in the leaf surfaces of R. chinensis. Fruit micromorphology and chromosome number of this species have also been evaluated.Bangladesh J. Plant Taxon. 25(1): 71-78, 2018 (June)
Lectotypification of Cryptocarya anamalayana Gamble (Lauraceae) with a note on its fruits
Authors: Bachan K.H. Amitha , Robi A.J. , Pradeep A.K. , Udayan P.S.
Published: June 2018

Not available.Bangladesh J. Plant Taxon. 25(1): 107-111, 2018 (June)
Behaviour-Based Husbandry—A Holistic Approach to the Management of Abnormal Repetitive Behaviors
Authors: Bacon Heather
Published: June 2018

The field of zoo animal welfare science has developed significantly over recent years. However despite this progress in terms of scientific research, globally, zoo animals still face many welfare challenges. Recently, animal welfare frameworks such as the five domains or five needs have been developed and suggested to improve the welfare of zoo animals, but without practical guidance, such tools may remain abstract from the daily experience of zoo animals. Similarly specific practical strategies such as those for enrichment development exist, but their lack of holistic integration with other aspects of animal husbandry and behavioral medicine means that overall, good zoo animal welfare may still be lacking. This paper outlines some of the barriers to implementing improved zoo animal welfare in practice, and proposes a new strategy for the development of behavioral husbandry routines focused on the management and mitigation of abnormal repetitive behaviors. Focusing on enhancing zoo animal welfare by integrating aspects of ecology, ethology and clinical animal behavior into a practical and comprehensive approach to behavior-based husbandry.
The Osteoclast in Bone Metastasis: Player and Target
Authors: Maurizi Antonio , Rucci Nadia
Published: June 2018

Bone metastases are frequently the final fate of breast and prostate cancer patients. According to the definition of metastasis as an incurable disease, to date there are no effective treatments for tumor-associated bone metastases and this represents a real challenge for the researchers in the field. The bone is a heterogeneous environment that represents a fertile soil for tumor cells, supporting their growth. Among the different cell types present in the bone, in this review we will focus our attention on the osteoclasts, which are crucial players in the so called “vicious cycle”, a phenomenon triggered by tumor cells eventually leading to both tumor proliferation as well as bone deregulation, thus fueling the development of bone metastasis. The complex network, linking tumor cells to the bone by activating osteoclasts, represents a fruitful target for the treatment of bone metastases. In this review we will describe how tumor cells perturb the bone microenvironment by actively influencing osteoclast formation and activity. Moreover, we will describe the current antiresorptive drugs employed in the treatment of bone metastases as well as new, targeted therapies able to affect both cancer cells and osteoclasts.
Marine Invertebrates: Underexplored Sources of Bacteria Producing Biologically Active Molecules
Authors: Rizzo Carmen , Lo Giudice Angelina
Published: June 2018

The marine bioprospecting could be considered as a new phenomenon, and already potentially more promising than terrestrial one in terms of possible discovery of new compounds. The secondary metabolites produced by associated-bacteria are actually studied for their remarkable role in several fields, including agricultural, industrial, medical, and bioremediation strategies against different contaminants. The use of such renewable sources could be helpful in the streamlining of the patenting process for natural compounds of good quality, produced with lower energy costs and less impact on the environment. Anyway, more improvements in the research and application of bioactive compounds as alternative to the synthetic counterparts have to be carried out for the costs reduction and the large-scale production upgrading. The use of marine invertebrates could help to overcome these difficulties, as hotspots of microbial diversity and favorable matrix for the development of conditions stimulating the production of substances with special activities. This review will deal with the current accepted definitions and recent advances concerning: (i) the marine symbiotic relationships in which microorganisms and invertebrates are involved; (ii) the principal taxa of marine invertebrates that establish interactions with microorganisms, the biodiversity of these latter, and their role in the symbiosis; (iii) we address the state of current literature and knowledge about the bacterial associated communities specialized in biosurfactants (BSs) and extracellular polymeric substances (EPSs) production; and, (iv) their potential biotechnological applications reported still now.
An Application of Maximal Exponential Models to Duality Theory
Authors: Santacroce Marina , Siri Paola , Trivellato Barbara
Published: June 2018

We use maximal exponential models to characterize a suitable polar cone in a mathematical convex optimization framework. A financial application of this result is provided, leading to a duality minimax theorem related to portfolio exponential utility maximization.
Parameter Identification of Pump Turbine Governing System Using an Improved Backtracking Search Algorithm
Authors: Zhou Jianzhong , Zhang Chu , Peng Tian , Xu Yanhe
Published: June 2018

Accurate parameter identification of pump turbine governing system (PTGS) is of great importance to the precise modeling of pumped storage unit. As PTGS is characterized by uncertainties and strong nonlinear characteristics, it is difficult to identify its parameters. To solve the parameter identification problem for PTGS, an improved backtracking search algorithm (IBSA) is proposed by combining the original BSA with the orthogonal initialization technique, the chaotic local search operator, the elastic boundary processing strategy and the adaptive mutation scale factor. The proposed IBSA algorithm for parameter identification of PTGS was applied on an illustrative example to demonstrate its accuracy and efficiency. The simulation results have shown that IBSA performed better compared with the particle swarm optimization, the gravitational search algorithm and the original BSA in regard to solution quality and parameter identification accuracy.
Nuclear Energy Development in Bangladesh: A Study of Opportunities and Challenges
Authors: Karim Ridoan , Karim Mohammad Ershadul , Muhammad-Sukki Firdaus , Abu-Bakar Siti Hawa , Bani Nurul Aini , Munir Abu Bakar , Kabir Ahmed Imran , Ardila-Rey Jorge Alfredo , Mas’ud Abdullahi Abubakar
Published: June 2018

It is a challenging task for Bangladesh to meet its increasing demand of energy while its economy is rapidly growing. Though prices of oil, coal, and fossil fuels around the world have been volatile, the price trend in Bangladesh demonstrates a persistent rise in the immediate past. This is further exacerbated by depleting reserves of natural gas. Cumulatively, these two effects heighten Bangladesh’s energy needs. Bangladesh presently mitigates her energy requirements predominantly through natural gas, supplemented by a handful of coal and furnace oil plants. Consequently, due to scarcity of natural gas, oil and coal resources, nuclear power surfaces as a palatable strategic option for Bangladesh’s future development agenda. However, a successful nuclear power program entails an extensive infrastructure. Just like the other nuclear energy-producing countries, Bangladesh also face challenges to safeguard the health and security of nuclear reactors, the proper management for nuclear waste treatment and the security concerns over the safe usage of nuclear materials. Additionally, the development of nuclear energy is also bewildered because of the complex nature of fission technology, lack of efficient human resources, and non-existence of proper legal instruments to guide safe nuclear power production. Moreover, the further challenges include the questions, for example: whether the nuclear power plant project is supported by the mass people or not? What are the strategies for nuclear waste disposal? Whether the recent initiatives for nuclear energy production is necessary or the country should more concern with renewable sources? This paper evaluates the nuclear energy development in Bangladesh. It operates under qualitative methodological framework and utilises secondary sources for analysis. We advance several recommendations in this paper to remedy the highlighted issues: (1) creating a comprehensive legal and regulatory system; (2) fortifying home-based technology of nuclear development and simultaneously localising of foreign-based technology; (3) reducing the cost of nuclear energy production; (4) fast-tracking the procedure of efficient development of nuclear technology; (5) accelerating the procedure of switching to more efficient reactor and nuclear fuel cycle, and (6) conducting effective profile-raising activities to generate greater awareness and spur common acceptance.
A Thermal Probability Density–Based Method to Detect the Internal Defects of Power Cable Joints
Authors: Zhang Li , LuoYang Xiyue , Le Yanjie , Yang Fan , Gan Chun , Zhang Yinxian
Published: June 2018

Internal defects inside power cable joints due to unqualified construction is the main issue of power cable failures, hence in this paper a method based on thermal probability density function to detect the internal defects of power cable joints is presented. First, the model to calculate the thermal distribution of power cable joints is set up and the thermal distribution is calculated. Then a thermal probability density (TPD)-based method that gives the statistics of isothermal points is presented. The TPD characteristics of normal power cable joints and those with internal defects, including insulation eccentricity and unqualified connection of conductors, are analyzed. The results indicate that TPD differs with the internal state of cable joints. Finally, experiments were conducted in which surface thermal distribution was measured by FLIR SC7000, and the corresponding TPDs are discussed.
Influence of the Design Parameters of a Fuel Thermal Management System on Its Thermal Endurance
Authors: Pang Liping , Li Shuxin , Liu Meng , A Rong , Li Aicheng , Meng Fanxin
Published: June 2018

The aerodynamic heating of a high-speed vehicle is destined to lead to a continuous fuselage temperature rise. However, its airborne thermal load rises exponentially. This will severely limit the thermal endurance of the high-speed vehicle and the working time of the electronic equipment. A jet-propelled high-speed vehicle usually uses fuel to generate thrust, so fuel thermal management technology has had much attention paid to it. During the vehicle design, its total amount of fuel should match its flight envelope. However, determining the amount of carried fuel is very difficult because it is affected by many factors. In order to analyze the relationship between the above influence factors and the flight envelope, a typical fuel thermal management system is set up for high-speed vehicles. Its dynamic characteristic equations are built correspondingly. A conception of thermal endurance is further presented to reveal the maximum flight time. Some flight conditions are used to analyze the influence of the main design parameters on the thermal endurance of high-speed vehicles. The results can help to design the parameters of fuel thermal management systems for high-speed vehicles.
Development of Honeycomb Methanation Catalyst and Its Application in Power to Gas Systems
Authors: Biegger Philipp , Kirchbacher Florian , Medved Ana Roza , Miltner Martin , Lehner Markus , Harasek Michael
Published: June 2018

Fluctuating energy sources require enhanced energy storage demand, in order to ensure safe energy supply. Power to gas offers a promising pathway for energy storage in existing natural gas infrastructure, if valid regulations are met. To improve interaction between energy supply and storage, a flexible power to gas process is necessary. An innovative multibed methanation concept, based on ceramic honeycomb catalysts combined with polyimide membrane gas upgrading, is presented in this study. Cordierite monoliths are coated with γ-Al2O3 and catalytically active nickel, and used in a two-stage methanation process at different operation conditions (p = 6–14 bar, GHSV = 3000–6000 h−1). To fulfill the requirements of the Austrian natural gas network, the product gas must achieve a CH4 content of ≥96 vol %. Hence, CH4 rich gas from methanation is fed to the subsequent gas upgrading unit, to separate remaining H2 and CO2. In the present study, two different membrane modules were investigated. The results of methanation and gas separation clearly indicate the high potential of the presented process. At preferred operation conditions, target concentration of 96 vol % CH4 can be achieved.
NF-kappaB Regulates Redox Status in Breast Cancer Subtypes
Authors: Pires Bruno , Binato Renata , Ferreira Gerson , Cecchini Rubens , Panis Carolina , Abdelhay Eliana
Published: June 2018

Oxidative stress (OS) is an indispensable condition to ensure genomic instability in cancer cells. In breast cancer (BC), redox alterations have been widely characterized, but since this process results from a chain of inflammatory events, the causal molecular triggers remain to be identified. In this context, we used a microarray approach to investigate the role of the main pro-oxidant transcription factor, nuclear factor-kappa B (NF-κB), in gene profiles of BC subtypes. Our results showed that NF-κB knockdown in distinct BC subtypes led to differential expression of relevant factors involved in glutathione metabolism, prostaglandins, cytochrome P450 and cyclooxygenase, suggesting a relationship between the redox balance and NF-κB in such cells. In addition, we performed biochemical analyses to validate the microarray dataset focusing on OS and correlated these parameters with normal expression or NF-κB inhibition. Our data showed a distinct oxidative status pattern for each of the three studied BC subtype models, consistent with the intrinsic characteristics of each BC subtype. Thus, our findings suggest that NF-κB may represent an additional mechanism related to OS maintenance in BC, operating in various forms to mediate other important predominant signaling components of each BC subtype.
DynSig: Modelling Dynamic Signaling Alterations along Gene Pathways for Identifying Differential Pathways
Authors: Shi Ming , Chong Yanwen , Shen Weiming , Xie Xin-Ping , Wang Hong-Qiang
Published: June 2018

Although a number of methods have been proposed for identifying differentially expressed pathways (DEPs), few efforts consider the dynamic components of pathway networks, i.e., gene links. We here propose a signaling dynamics detection method for identification of DEPs, DynSig, which detects the molecular signaling changes in cancerous cells along pathway topology. Specifically, DynSig relies on gene links, instead of gene nodes, in pathways, and models the dynamic behavior of pathways based on Markov chain model (MCM). By incorporating the dynamics of molecular signaling, DynSig allows for an in-depth characterization of pathway activity. To identify DEPs, a novel statistic of activity alteration of pathways was formulated as an overall signaling perturbation score between sample classes. Experimental results on both simulation and real-world datasets demonstrate the effectiveness and efficiency of the proposed method in identifying differential pathways.
The At Risk Child Clinic (ARCC): 3 Years of Health Activities in Support of the Most Vulnerable Children in Beira, Mozambique
Authors: Marotta Claudia , Di Gennaro Francesco , Pizzol Damiano , Madeira Geoffrey , Monno Laura , Saracino Annalisa , Putoto Giovanni , Casuccio Alessandra , Mazzucco Walter
Published: June 2018

The concept of “children at risk” changes worldwide according to each specific context. Africa has a large burden of overall risk factors related to childhood health and development, most of which are of an infective or social origin. The aim of this study was to report and analyze the volumes of activities of fifteen At Risk Child Clinics (ARCCs) within the Beira District (Mozambique) over a 3 year-period in order to define the health profile of children accessing such health services. We retrospectively analyzed the data from all of the children accessing one of the 15 Beira ARCCs from January 2015 to December 2017. From this, 17,657 first consultations were registered. The motivations for accessing the services were in order of relevance: HIV exposure (n. 12,300; 69.7%), other risk conditions (n. 2542; 14.4%), Moderate Acute Malnutrition (MAM) (n. 1664; 9.4%), Severe Acute Malnutrition (SAM) (n. 772; 4.4%), and TB exposure (n. 542; 3.1%). During the first consultations, 16,865 children were screened for HIV (95.5%), and 7.89% tested HIV-positive. In our three years of experience, HIV exposure was the main indication for children to access the ARCCs in Mozambique. ARCCs could represent a strategic point to better understand health demands and to monitor the quality of care provided to this vulnerable population group, however significant effort is needed to improve the quality of the data collection.
Upstream-Downstream Joint Carbon Reduction Strategies Based on Low-Carbon Promotion
Authors: Xia Xiqiang , Ruan Junhu , Juan Zhiru , Shi Yan , Wang Xuping , Chan Felix T. S.
Published: June 2018

A differential game model is established to analyze the impact of emissions reduction efforts and low-carbon product promotion on the reduction strategies of low-carbon product manufacturers (subsequently referred to as manufacturers) and the retailers of such products in a dynamic environment. Based on this model, changes in emissions reduction efforts and promotional efforts are comparatively analyzed under three scenarios (retailers bearing the promotional cost, manufacturers bearing the promotional cost, and centralized decision-making). The results are as follows: (1) the trajectory of carbon emissions reduction per product unit is the highest when the supply chain is under centralized decision-making, followed by when manufacturers bear the promotional cost, and lastly when retailers bear the cost; (2) when manufacturers bear the promotional cost, the market demand, emissions reduction effort, and promotional effort are higher, although the unit retail price is higher than when retailers bear the promotional cost; and (3) under centralized decision-making, the unit retail price is the lowest; however, sales volume, the emissions reduction effort, and the promotional effort are all higher than those in the other scenarios.
Regulation of Root Development and Architecture by Strigolactones under Optimal and Nutrient Deficiency Conditions
Authors: Marzec Marek , Melzer Michael
Published: June 2018

Strigolactones (SLs) constitute a group of plant hormones which are involved in multiple aspects of plant growth and development. Beside their role in shoot and root development and plant architecture in general, SLs are also involved in plant responses to nutrient deficiency by promoting interactions with symbiotic organisms and via promotion of root elongation. Recent observations on the cross talk between SLs and other hormones demonstrate that the inhibition of adventitious root formation by ethylene is independent of SLs. Additionally, it was shown that root exposure to SLs leads to the accumulation of secondary metabolites, such as flavonols or antioxidants. These data suggest pleiotropic effects of SLs, that influence root development. The discovery that the commonly used synthetic SL analogue racGR24 might also mimic the function of other plant growth regulators, such as karrikins, has led us to consider the previously published publications under the new aspects. This review summarizes present knowledge about the function of SLs in shaping root systems under optimal and nutrient deficiency conditions. Results which appear inconsistent with the various aspects of root development are singled out.
Newborn Screening for Lysosomal Disease: Mission Creep and a Taste of Things to Come?
Authors: Wilcken Bridget
Published: June 2018

Newborn screening for several lysosomal disorders can now be accomplished successfully for case finding. However, many cases identified do not require immediate intervention and it is not yet clear, for some disorders, if there is a benefit in early diagnosis for those cases, or what should be called a benefit. Diagnosing adult-onset cases, especially when there are quite imperfect genotype-phenotype correlations, represents a significant expansion of what has heretofore been considered the aim of newborn screening. This mission creep should be carefully discussed, and certain aspects of newborn screening strengthened. We should all proceed with caution in this field.
Hybrid Metasurface Based Tunable Near-Perfect Absorber and Plasmonic Sensor
Authors: Rifat Ahmmed A. , Rahmani Mohsen , Xu Lei , Miroshnichenko Andrey E.
Published: June 2018

We propose a hybrid metasurface-based perfect absorber which shows the near-unity absorbance and facilities to work as a refractive index sensor. We have used the gold mirror to prevent the transmission and used the amorphous silicon (a-Si) nanodisk arrays on top of the gold mirror which helps to excite the surface plasmon by scattering light through it at the normal incident. We numerically investigated the guiding performance. The proposed absorber is polarization independent and shows a maximum absorption of 99.8% at a 932 nm wavelength in the air medium. Considering the real applications, by varying the environments refractive indices from 1.33 to 1.41, the proposed absorber can maintain absorption at more than 99.7%, with a red shift of the resonant wavelength. Due to impedance matching of the electric and magnetic dipoles, the proposed absorber shows near-unity absorbance over the refractive indices range of 1.33 to 1.41, with a zero-reflectance property at a certain wavelength. This feature could be utilized as a plasmonic sensor in detecting the refractive index of the surrounding medium. The proposed plasmonic sensor shows an average sensitivity of 325 nm/RIU and a maximum sensitivity of 350 nm/RIU over the sensing range of 1.33 to 1.41. The proposed metadevice possesses potential applications in solar photovoltaic and photodetectors, as well as in organic and bio-chemical detection.
Novel Negative Poisson’s Ratio Lattice Structures with Enhanced Stiffness and Energy Absorption Capacity
Authors: Chen Zeyao , Wang Zhe , Zhou Shiwei , Shao Jianwang , Wu Xian
Published: June 2018

The weak stiffness and strength of materials with negative Poisson’s ratio limits their application. In this paper, three types of novel lattices with negative Poisson’s ratio are proposed to improve not only stiffness and strength but also energy absorption capacity by embedding different ribs into a classic re-entrant structure. Unit cell analyses show these novel lattices have significantly increased Young’s modulus along the loading direction, and Type C can maintain sufficient negative Poisson’s ratio performance compared with the base lattice. In addition, the novel lattices exhibit higher yield stress, plateau stress and densification strain extracted from quasi-static compressive simulation. The lattices are prototyped by laser-based additive manufacturing and tested in quasi-static experiments, which show the experimental data match the numerical results within an error of margin. The work signifies the prospect of lattices with negative Poisson’s ratio in enhancing engineering-applicable structures, and indicates the potential of structural topology optimization in more sophisticated designs.
Titanium Oxide (TiO2)/Polymethylmethacrylate (PMMA) Denture Base Nanocomposites: Mechanical, Viscoelastic and Antibacterial Behavior
Authors: Alrahlah Ali , Fouad H. , Hashem Mohamed , Niazy Abdurahman A. , AlBadah Abdulhakim
Published: June 2018

Currently, polymethylmethacrylate (PMMA) is the most popular denture base material. Most fractures of dentures that occur during function are due to its insufficient mechanical strength. The major drawbacks of PMMA are insufficient ductility, strength, and viscoelastic behavior. The purpose of this study was to evaluate a polymethylmethacrylate denture base material modified with TiO2 nanoparticles in terms of nanomechanical, creep-recovery, and relaxation. Additionally, the effects of addition TiO2 nanoparticles on the thermal and antimicrobial adhesion behaviors were investigated. Differential scanning calorimetry and thermogravimetric analysis indicated that the effect of small amounts of TiO2 nanoparticles (1 wt. %, 2 wt. %, and 3 wt. %) on the degradation behavior of PMMA denture bases was insignificant. The nanomechanical test results of the PMMA and PMMA/TiO2 nanocomposites indicated that the hardness and modulus in the nanoscale range improved due to TiO2 addition. At a 1200-nm penetration depth, the modulus increased by 10%, 16%, and 29% and hardness increased by 18%, 24%, and 35% with the addition of 1 wt. %, 2 wt. %, and 3 wt. % TiO2, respectively. Furthermore, the creep-recovery and relaxation behaviors of PMMA were significantly improved due to the addition of TiO2. The creep strain decreased from 1.41% to 1.06%, 0.66%, and 0.49% with the addition of 1 wt. %, 2 wt. %, and 3 wt. % TiO2, respectively. The relaxation test results showed that the initial stress under 1% strain improved to 19.9, 21.2, and 22 MPa with the addition of 1 wt. %, 2 wt. %, and 3 wt. % TiO2, respectively. The improvement in the nanohardness, modulus, creep recovery, and relaxation behavior of PMMA due to the addition of TiO2 nanoparticles indicated the role of the nanoparticles in increasing the PMMA matrix stiffness by reducing its mobility and free volume. TiO2 nanoparticles also improved the antimicrobial behavior of PMMA by significantly reducing bacterial adherence with increasing TiO2 ratio.
Osteoblast Cell Response to Naturally Derived Calcium Phosphate-Based Materials
Authors: Mitran Valentina , Ion Raluca , Miculescu Florin , Necula Madalina Georgiana , Mocanu Aura-Catalina , Stan George E. , Antoniac Iulian Vasile , Cimpean Anisoara
Published: June 2018

The demand of calcium phosphate bioceramics for biomedical applications is constantly increasing. Efficient and cost-effective production can be achieved using naturally derived materials. In this work, calcium phosphate powders, obtained from dolomitic marble and Mytilus galloprovincialis seashells by a previously reported and improved Rathje method were used to fabricate microporous pellets through cold isostatic pressing followed by sintering at 1200 °C. The interaction of the developed materials with MC3T3-E1 pre-osteoblasts was explored in terms of cell adhesion, morphology, viability, proliferation, and differentiation to evaluate their potential for bone regeneration. Results showed appropriate cell adhesion and high viability without distinguishable differences in the morphological features. Likewise, the pre-osteoblast proliferation overtime on both naturally derived calcium phosphate materials showed a statistically significant increase comparable to that of commercial hydroxyapatite, used as reference material. Furthermore, evaluation of the intracellular alkaline phosphatase activity and collagen synthesis and deposition, used as markers of the osteogenic ability of these bioceramics, revealed that all samples promoted pre-osteoblast differentiation. However, a seashell-derived ceramic demonstrated a higher efficacy in inducing cell differentiation, almost equivalent to that of the commercial hydroxyapatite. Therefore, data obtained demonstrate that this naturally sourced calcium-phosphate material holds promise for applications in bone tissue regeneration.
Psychosocial job characteristics, social support, and sense of coherence as determinants of mental health among nurses
Authors: Malinauskienė Vilija , Leišytė Palmira , Malinauskas Romualdas
Published: June 2018

Objective. Employment in human service occupations as nursing is reported to display high risk for mental health, and occupational stress has been found to be one of the major work-related health problems. The objective of the study was to explore the associations between psychosocial job characteristics, social support, and internal resources as determinants of mental health status in a sample of Kaunas district nurses. Material and methods. A survey was conducted among the nurses of Kaunas district community in 2008–2009. A total of 638 nurses were randomly selected, and 372 filled in the questionnaire (response rate, 58.3%). Mental distress was measured using the Goldberg 12-item General Health Questionnaire and psychosocial job characteristics using the Swedish version of the Karasek Demand-Control questionnaire. Sense of coherence was measured by the three-item version questionnaire. The logistic regression was performed. Results. Less than one-third (23.0%) of nurses had symptoms of mental distress; 31.9% of nurses had weak sense of coherence. High job demands were associated with mental distress after adjustment for age, smoking, alcohol consumption, physical activity, job control, social support, sense of coherence, family crisis, self-rated health as compared to one year ago (OR=2.15; 95% CI, 1.07–4.30), low job control (OR=1.22; 95% CI, 0.64–2.31), job strain-low social support at work (OR=3.78; 95% CI, 2.08–6.87). Conclusions. Mental distress among the nurses of Kaunas district was associated with adverse psychosocial job characteristics. Job strain-low social support at work was the strongest risk factor for mental distress among nurses. Strong sense of coherence as personal characteristic served as a buffer, protecting nurses against the development of mental health problems.
Acquired immunodeficiency syndrome and opportunistic infections
Authors: Dvaranauskaitė Lina , Vėlyvytė Daiva , Kurklietytė Virginija , Gumbelevičius Antanas , Keleras Evaldas , Laiškonis Alvydas , Mickienė Auksė
Published: June 2018

This article presents a clinical case of late diagnosis of cerebral toxoplasmosis and cytomegalovirus retinitis of right eye in a 32-year-old patient who was unaware of her HIV status. In addition, this article reviews the literature reflecting clinical, diagnostic, and treatment issues of some opportunistic infections in AIDS.