bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Dietary Docosahexaenoic Acid (DHA) for Cognitive Function
Authors: Hamda Nisma , R Navaneetha
Published: June 2022

Abstract: Docosahexaenoic acid (DHA) is a structural component of membranes in the Central Nervous System (CNS). Docosahexaenoic acid and eicosapentaenoic acid (EPA) are two long-chain polyunsaturated fatty acids known as “omega-3 fatty acids” and they have beneficial effects in a variety of organs and biological processes, including growth regulation and platelet activation. Brain structure and function rely on a constant and sufficient supply of EPA and DHA. It builds up in the fetal brain mostly during the third trimester of pregnancy and continues at high rates of accumulation until the end of the second year of life. At birth the proportion of brain weight to the body weight is 70% when compared to their proportions in adults, and 15% of brain growth occurs throughout the preschool years. The majority of brain development occurs between the age of 5 and 6 years. DHA is also essential for adults to maintain optimal brain function. The Google search engine, mdpi, kva, Cambridge, Elsevier, and karger were used to conduct a literature search on DHA. DHA is found in fatty fish such as salmon, mackerel, and tuna, as well as mother’s milk. Meat and eggs contain low quantity of DHA. Long chain omega-3 fatty acids and DHA supplementation has shown to improve the brain cognitive performance in various studies. Keywords: Docosahexaenoic acid, eicosapentaenoic acid, central nervous system, omega-3 fatty acid, cognitive function and development.
War Crimes and Crime of Genocide: Does the Laws really prevent Crimes in the Modern Society
Authors: Ghosh Arnab Kumar
Published: June 2022

Abstract: The term Genocide and War Crimes is as old as the existence of the first social groups formed in human society which started happening throughout the generation. Each of those concepts has followed its own path and definition but sometimes there are considerable overlaps among them. These overlaps require progressive codification where both confirmed and reaffirmed in an effort to stop and punish the commission of such acts. It’s a very obvious question when the term war crime was used for the first time and when the first war crimes were committed during history by some famous empire that termed it in their own primitive societies. It was very common in between the wars or battles that were concluded by sacking a particular region after defeating them, and by slaughtering the soldiers’ and capturing the civilians. But at that time it was common war behavior by the successor party and never thought of considering it as war crimes. As far as genocide is concerned, this crime was first time codified under International Law and acted more swiftly than war crimes as some nightmare incident happened during World War II done by world’s greatest Nazi party. These crimes are also severe inhuman offenses which are committed in the most brutal way of violation of any human law. I have also tried to discuss the recent conflicts between Russia and Ukraine related to NATO discussion and how superpower countries using their powers just to make ensure their countries are as safe as heaven. These all wars led to War Crimes rise of War Criminals, and thousand to genocide cases. These atrocities crimes effect the future generation physically, mentally and with chemical sediments of those immigrants. Till date it is a major problem throughout the globe and especially in our country, which directs us to different riots, protests and other events without declaring it as genocide or any crime towards society. In this paper, I have tried to explore some facts and crime in detailed manner by covering the entire concept and how this concept of war crime and genocide affects the society, the social health and mental health of the people and some various definitions and law which till date people are unaware to such type of incident by calling them a simple crime or murder. Thus, this paper tries to analyze the difference which will help to understand the wholesome meaning and ideas of this atrocity crime. Keywords: Genocide, War, Generation, Crime, Atrocity.
Android Based Home Automation System
Authors: Yelorkar Prof. Deepak , Kadam Harpita , Bhosle Sahil , Gosavi Atharva , Taru Dnyanal
Published: June 2022

Abstract: Home automation involves introducing a degree of computerized or automatic control to certain electrical and electronic systems in a building. A hardware system is installed to monitor and control the various appliances. The system would control the appliances based on its configuration. For example, it could automatically turn on the lights at a specified time in the evening, or it could measure the ambient light using a hardware sensor and turn on the lights when it grows dark. For example, one could turn on the air conditioning from the office, before leaving for home. This project demonstrates a simple home automation system that allows the user to control it with a wireless device such as a Bluetooth enabled mobile phone. The system allows the user to control each of the lights and fans individually. It can automatically turn off the main lights and turn on a night lamp at a specified time. By measuring the signal strength, it can detect when the user enters a room and automatically turn on the light and fans, and then automatically turn them off when the user leaves the room. Keywords: Home automation, electronics, hardware system, wireless devices and Bluetooth etc.
Comparative Analysis of Performance and Emission Characteristics of Diesel and Bio-Diesel as A Fuel in VCR Engine
Authors: Pal Shivam , Srivastav Akshit , Maurya Ankit , Yadav Devang , Yadav Abhishek
Published: June 2022

Abstract: The соnсerns оn сlimаte сhаnge, the high energy рriсes аnd the dwindling оil reserves аnd suррlies hаve neсessitаted а strоng interest in the reseаrсh оf аlternаtive fuel sоurсes. Biоdiesel is аn аlternаtive renewаble fuel thаt hаs gаined mаssive аttentiоn in reсent yeаrs. Studies оn the рhysiсаl рrорerties оf biоdiesel hаve shоwn thаt it is соmрletely misсible with рetrоleum diesel. Sinсe the соmbustiоn оf biоdiesel emits раrtiсulаte mаtter аnd gаses whiсh is lоwer thаn рetrоdiesel, соmbustiоn оf biоdiesel аnd biоdiesel blends hаve shоwn а signifiсаnt reduсtiоn in раrtiсulаte mаtter аnd exhаust emissiоns. In this review рарer, the use оf рure biоdiesel оr biоdiesel blends in terms оf рerfоrmаnсe аnd exhаust emissiоns hаs been studied in соmраrisоn tо рetrоleum diesel minerаl diesel. Соmbustiоn durаtiоn fоr biоdiesel blends wаs shоrter thаn minerаl diesel. Keywords: Neem biodiesel, Global warming, Transesterifications, Pour point , Break power, Emission Characteristic
Exploration of Sam Poo Kong Building Heritage as Starting Point in Geometric Transformation Course
Authors: Aisyah Fifin , Lestari Aidha Aprilia Puji , Supriyanto Muhammad Agus , Nursyahidah Farida
Published: June 2022

Sam Poo Kong is one of Semarang's city cultural heritages. This historical structure features intriguing architecture as well as being a popular tourist destination.  This study aims to explore Sam Poo Kong's building as a starting point in the geometric transformation course. Besides, the study method is descriptive in qualitative terms with the ethnography approach, namely the type of research to describe and acquire data as a whole, comprehensive, and in-depth. The result is an ethnomathematics exploration of Sam Poo Kong's historic buildings, representing mathematical concepts including reflection, translation, rotation, dilation, and cultural values. Based on implementation in transformation class, students can quickly grasp which Sam Poo Kong's building portrays transformation.Students can identify and describe the Sam Poo Kong building's transformation forms, which include: 1) reflection on the temple as a whole, ornaments, and Sam Poo Kong entrance gates; 2) translation on the statues, roofs, lanterns, and poles; 3) rotation on the bedug, reliefs, incense holders, lanterns, and anchors; and 4) dilatation of the inner and outer rooflines of the Sam Poo Kong building. This can stimulate students to envisage the types of transformation, which makes the information easier to learn.Moreover, this study can benefit teachers for local wisdom context reference in geometric transformation and following researchers for further study.
An Analysis of the Ability to Understand Mathematical Concepts of Middle School Students in Completing Integer Operations
Authors: Wibowo Teguh , Darmono Prasetyo Budi , Azieta Haliza Nur
Published: June 2022

Understanding mathematical concepts is a crucial skill for students to possess because it will make it easier for students to learn and master concepts in mathematics. This study aimed to describe the ability to understand mathematical concepts of junior high school students in solving integer arithmetic operations. This type of research was descriptive qualitative. The subjects in this study were seventh-grade students in one of the public junior high schools in Purworejo district in the 2020/2021 academic year with a good understanding. The technique of selecting the subject was purposive and snowball. The data analysis technique employed was the analysis technique of Miles & Huberman; data reduction, data presentation, and conclusion drawing. The results of this study indicated that students' understanding of mathematical concepts in completing arithmetic operations were as follows; students could restate a concept in writing, students could provide examples and not examples of a concept they have learned, students could use and choose certain operations in solving mathematical problems, students could not present concepts in the form of mathematical representations in the form of pictures, students could not classify objects according to certain properties according to the concept, and students could not apply the concept algorithmically to problem-solving.
Seed germination requirements and responses to salinity and water stress of Centaurea eriophora
Authors: Bouker Amar , Mehdadi Zoheir , Latreche Ali , Saidi Boubakr
Published: June 2022

Centaurea eriophora L. (Asteraceae) is a rare annual plant, found in some Mediterranean regions and requiring conservational measures. The present study was carried out to highlight the species germination behavior under two controlled environmental constraints: salt and water stress. Achenes collected on Mount Tessala (North-West Algeria) were germinated under a water potential gradient (0 to –2.45 MPa) induced by different concentrations of polyethylene glycol and under different concentrations of NaCl (0 to 102 mM). The experiments were conducted at constant temperature. The obtained results showed a high significant effect of salinity and water stress, especially on final germination percentage, while the highest germination (85%) was obtained at control conditions in both of the tests. Under salinity and water stress conditions, there was a significant deterioration in most germination parameters, particularly a lower final germination percentage. The tolerance thresholds for salinity and water deficit were 68 mM and –1.2 MPa respectively. Beyond these values, seed germination of C. eriophora was completely inhibited. The sensitivity of C. eriophora achenes to environmental pressures should be considered in the long-term effective conservation plans.
Adherence of Aeromonas veronii, Shigella flexneri and Escherichia fergusonii with Microcystis-dominated bloom relates to their ability to utilize chitin
Authors: Dwivedi Pushpendra Kumar , Bagchi Divya , Bagchi Suvendra Nath
Published: June 2022

The study was undertaken to size-fractionate the bacterial population associated with Microcystis blooms of an eutrophic lake. Two bacterial cultures were isolated from the particulate-bound fraction, and biochemical tests, phylogenetic analysis and homology of 16S rRNA gene sequences revealed their high similarity with Aeromonas veronii and Shigella flexneri. Another isolate with characteristics resembling Escherichia fergusonii was obtained in phytoplankton-free water samples. Since these three cultures were enriched on chitin-selective medium, their capability to utilize chitin as a sole C source was examined. The in vivo chitinase activity (as µg N‑acetyglucosamine produced min–1 mL–1 culture) was 82.1, 28.5 and 18.5 for A. veronii, S. flexneri and E. fergusonii, respectively. The corresponding N‑acetylglucosamine accumulation in medium was 421, 288 and 122 µg mL–1. There was also a gradation in growth indices in the three bacteria, which corresponded to their chitin utilization ability. Notwithstanding differences in chitinase activity, the three strains utilized almost equally the exogenous N‑acetylglucosamine. We propose that chitinase activity may have a role in affinity of the particular bacterial cell to phytoplankton extracellular polymeric substances and therefore, adherence ability.
Optimal Hierarchical Control of Isolated Microgrids
Authors: Alzate-Castaño Ricardo , Mantilla-Villalobos María Alejandra
Published: June 2022

The objective of this article is to propose a novel method that uses hierarchical control to efficiently manage power resources in an isolated Direct Current (DC) microgrid. The scope of this paper is limited to a numerical study of the components of the micro-generation system using accurate mathematical models in a commercial simulation tool. The control methodology is based on power sharing by means of a hierarchical topology including several control layers. In particular, the internal control loops that regulate the electrical variables in individual generators are at the bottom of the hierarchy. In addition, the power-sharing technique distributes power at an intermediate level, and it is complemented by a Newton-Raphson optimization algorithm at the top, which aims to minimize the cost function. The cost of the microgrid is defined in terms of investment and maintenance indices. This study analyzes the case of a low-power isolated DC microgrid that combines an array of photovoltaic panels and a battery bank. The most relevant result was the optimization of its generation cost, which was verified using simulations of the control and power circuits. In conclusion, although simple, the proposed technique achieves efficient performance in managing the power resources of this microgrid under environmental disturbances.
De extraer a circular: enfoques de la protección ambiental
Authors: Jaramillo Zapata Leyla
Published: June 2022

La preocupación por el ambiente, el planeta y nuestro futuro no es reciente, ya que ha evolucionado a través de las décadas, y en la actualidad es un tema global que nos involucra a todos. Sin embargo, la evolución de la protección ambiental ha estado marcada por algunos aspectos que caracterizan cada época.
IMPROVING OBSERVATION REPORT TEXT WRITING SKILLS THROUGH THE IMPLEMENTATION OF PROBLEM-BASED LEARNING MODEL USING POWTOON APPLICATION IN JUNIOR HIGH SCHOOL
Authors: Septiana Sinta Dinar , Wuryaningrum Rusdhianti , Syukron Akhmad
Published: June 2022

The skill of writing observation report text is one of the skills that need to be mastered by class X high school students. Based on the results of observations and interviews with Indonesian language subject teachers at Arjasa Junior High School, there is a problem in the process of writing observation report text. Students have d ifficulties in starting and developing ideas, have errors in applying linguistic rules, and difficulties in compiling a text framework for the observation report. This is indicated by the low-level of difficulty in learning to write the text of the observation report: only 7 students whose grades have reached the standard grade Standard Score, 28 students do not complete. To improve the writing skills of the observation report text, it is necessary to take action by applying the Problem Based Learning (PBL) model combined with the powtoon application media. The research design used was CAR (Classroom Action Research) which consisted of two cycles starting from planning, action, observation, reflection, re-planning, action, observation, and reflection. The method used to get data is through questionnaires, interviews, observations, tests, and documentation. The results showed that student learning outcomes increased from cycle I to cycle II, namely by 45.7% or as many as 16 students who reached the standard grade increased to 80% or as many as 28 students in cycle II. Based on the results obtained, it can be concluded that the application of the PBL model with the powtoon application media can improve students' skills in writing observation report text in class X IPA 4 Arjasa Junior High School.
Unveiling biogeographic patterns in the worldwide distributed Ceratitis capitata (medfly) using population genomics and microbiome composition
Authors: Arias María Belén , Hartle-Mougiou Katherine , Taboada Sergi , Vogler Alfried , Riesgo Ana , ELFEKIH SAMIA
Published: June 2022

Invasive species are among the most important, growing threats to food
security and agricultural systems. The Mediterranean fruit fly Ceratitis
capitata is one of the most damaging representatives of a group of
rapidly expanding species in the family Tephritidae due to their wide
host range and high invasiveness. Here, we used restriction
site-associated DNA sequencing (RADseq) to investigate population
genomic structure and phylogeographic history of medflies collected from
six sampling sites, including Africa (South Africa), the Mediterranean
(Spain, Greece), Latin America (Guatemala, Brazil) and Australia. A
total of 1,907 single nucleotide polymorphisms (SNPs) showed two genetic
clusters separating native and introduced ranges, consistent with
previous findings. In the introduced range, all individuals were
assigned to one genetic cluster except for those in Brazil, which showed
introgression of a genetic cluster that also appeared exclusively in
South Africa and could not be previously identified using microsatellite
markers. Moreover, the microbiome variations in medfly populations from
selected sampling sites was assessed by amplicon sequencing of the 16S
ribosomal RNA (V4 region). No strong patterns of microbiome variation
were detected across geographic regions or host plants, except for the
differentiation of the Brazilian specimens which showed increased
diversity and unique composition of its microbiome compared to other
sampling sites. The unique SNP patterns in the Brazilian specimens could
point to a direct migration route from Africa with subsequent adaptation
of the microbiota to the specific conditions present in Brazil. These
findings significantly improve our understanding of the evolutionary
history of global medfly invasions and adaptation to newly colonised
environments.
How many fathers? Study design implications when inferring multiple paternity in crocodilians.
Authors: Isberg Sally
Published: June 2022

Up to ten males have been reported to sire clutches of crocodilian eggs
but review of the underlying study designs raised questions of potential
upward bias of inferred sire numbers. To test this premise, different
scenarios were explored using a published dataset of 16 known
single-sire saltwater crocodile pairs and their offspring which were
originally confirmed using an 11 loci microsatellite panel in CERVUS.
Varying the number of microsatellites, omitting one or both parental
genotypes and using different parentage analysis techniques revealed
that total allele number, rather than number of loci, determined
inferred sire accuracy in two opposing ways. Using the single-locus
minimum method and GERUD, which both require prior knowledge of family
groupings (ie nests), fewer alleles (and loci) accurately inferred only
one father. In contrast, CERVUS and COLONY required all 11 loci (65
alleles) and both parental genotypes to (a) assign correct family groups
and (b) infer the correct sire number, except in one family where two
sires were equally assigned based on their number of homozygous loci.
When less genotype information was provided, CERVUS and COLONY inferred
up to six and seven sires, respectively. Consequently, crocodilian
maternal genotypes should at least be obtained either directly (blood,
tissue) or indirectly (eggshells, eDNA) in addition to a representative
population sample of adult genotypes before embarking on multiple
paternity determination. Running different scenarios using different
analytical methods and reporting on the lowest number of inferred sires
is encouraged remembering these sires are hypothetical until proven by
true genotype.
Genetic diversity of Cordia myxa L. assessed by ISSR markers
Authors: Nikkhah Maryam , Arbabian Sedigheh , Majd Ahmad , Sharifnia Fariba
Published: June 2022

A large number of species of Cordia (Boraginaceae) are found across the
tropical and subtropical parts of the planet. Cordia species are mentioned
in popular medicine as being used to cure a variety of ailments affecting a
variety of human organs. Population genetic structure, genetic diversity,
and phenotypic variation are unknown for this species in Iran. For this
reason, we collected morphological as well as molecular data on this plant
species, which is significant in its own right. We employed 70 plants that
were randomly picked from seven geographical communities spread throughout
four provinces to conduct our research. These populations' genetic diversity
variables were analyzed. The results of the structure and K-Means grouping
analyses indicated the existence of five distinct gene pools in the nation,
which were isolated from one another geographically. Genetic and
geographical separation were shown to be correlated using the Mantel
analysis. Among communities, AMOVA found considerable genetic differences,
with within-population variance accounting for around 55% of the overall
genetic variability. Upcoming breeding and conservation efforts for this
vital medicinal plant in the nation may benefit from these findings.
Identification of genetic diversity in wild pear (Pyrus elaeagrifolia Pall.) genotypes collected from different regions of turkey with SSR marker system
Authors: Uzun Aydın , Pinar Hasan , Yaman Mehmet , Yigit Merve , Cakiroglu Yaşar , Karakaya Arif , Uysal Mehmet , Ozturk Gökhan , Yilmaz Kadir , Gurcan Kahraman , Ercisli Sezai
Published: June 2022

Turkey with diverse ecologies is among the unique countries in terms of plant
species and diversity. Among these plant species, naturally growing wild
pears (Pyrus elaeagrifolia Pall.) are resistant to chlorosis and drought and
could be used in rootstock development programs. In present study, genetic
diversity in 96 wild pear genotypes collected from 11 different provinces
(Kayseri, Ankara, Kahramanmara?, Adana, Nev?ehir, Konya, Isparta, Denizli,
U?ak, Afyonkarahisar, Eski?ehir) and regions of Turkey through selection was
investigated with the use of SSR (Simple Sequence Repeat) molecular marker
system. Present analyses carried out in ABI (Applied Biosystem) 3500
capillary electrophoresis system revealed 93 scorable and all polymorphic
bands, thus polymorphism rate was 100%. In UPGMA (Unweighted pair group
method with arithmetic mean) dendrogram of wild pear genotypes, similarity
index values varied between 0.20-0.83 and a large variation was observed
among the genotypes. Present finding may have significant contributions to
further studies to be conducted for preservation of gene sources and
breeding of wild pear genotypes.
Species identification and genetic diversity of Alcea (Malvaceae) using SCoT molecular markers: Medicinal plant
Authors: Sun Yanxia , Jiang Hanxiu , Zeng Fang , Pan Xin , Wu Xiaoxia , Qi Yue , Wu Xiaoyong
Published: June 2022

The genus Alcea that is a member of Malvaceae family, is a Mediterranean
perennial herb with major diversity centers in the Middle East and Western
Mediterranean Basin. Alcea is a unique genus with several endemic taxa, and
many of these endemic taxa from the Irano-Turanian phytogeographical area
are particularly interesting. The genus contains 34 species in Iran, 15 of
which are endemic. As a result of the importance of Alcea species, molecular
data were collected for this genus in this research. For this study, 83
plants were used, which were randomly obtained from 5 species found in 6
provinces. Genomic DNA Amplification with 5 primers resulted in 75 bands, 66
of which were polymorphic (88.12%). The high average MI and PIC values
indicated that SCoT primers have a high capacity for detecting polymorphic
loci among the species of Alcea. The range of genetic similarities between 5
collected species was estimated to be between 0.77 and 0.89. The SCoT
markers analysis revealed that the species Alcea angulata and Alcea popovii
had the least similarity, while Alcea loftusii and Alcea sulphurea had the
most similarity. The current study?s objectives are as follows: 1) is it
possible to identify Alcea species through SCoT markers, 2) what genetic
structure do these species have in Iran, and 3) what is the species
inter-relationship? The current research found that SCoT markers can be used
to identify the species.
Clinical exome sequencing in Serbian patients with movement disorders: Single centre experience
Authors: Brankovic Marija , Dragasevic Natasa , Dobricic Valerija , Maver Ales , Bergant Gaber , Petrovic Igor , Peric Stojan , Marjanovic Ana , Jankovic Milena , Jancic Jasna , Novakovic Ivana , Peterlin Borut , Svetel Marina , Kostic Vladimir
Published: June 2022

The aim of the study was to analyze the genetic basis of a various range of
neurodegenerative disorders manifesting by movement disorders (MD) using
next generation sequencing (NGS) clinical exome panel. The study included a
total number of 42 cases, 36 unrelated and 3 sibling pairs patients
diagnosed with movement disorders, all negative after targeted genetic
testing available at Neurology clinic, UCCS, Belgrade, Serbia. In a
selection of respondents, preference was given to family cases with the
early presentation, patients with a positive family history, or complex MD
phenotype. Sequencing of a Clinical exome (CE) panel for 4813 genes with
known associated clinical phenotypes was performed on an Illumina MiSeq NGS
platform according to the manufacturer?s instructions. Sequence variants
were analyzed by Illumina?s Variant Studio v3 software as well as using
previously developed pipeline. Variants analysis and interpretation were
based on phenotype gene target approach, literature and databases search,
allele frequency, and pathogenicity prediction by in silico software.
Causative variants were confirmed by Sanger sequencing. Whenever possible,
additional family members were studied for segregation analysis. We
identified a likely genetic cause of MD in 5 cases. CE panel analysis
revealed 7 different missense and one splice site pathogenic/likely
pathogenic variants in 5 genes related to rare neurodegenerative disorders.
Detected pathogenic/likely pathogenic variants in the TUBB4A, PANK2, SETX,
MFSD8, and ARSA genes have been compatible with the clinical phenotype of
the patients. Furthermore, in additional three cases variants in the DCTN1,
PDGFRB, and POLG genes have been detected as a possible cause of disease. In
the rest of the studied cases, genetic diagnosis remains unclear. These
results emphasize the significance of CE panel analysis in elucidating the
diagnosis of neurodegenerative diseases manifesting by movement disorders
and gave us insight into the complexity of the genetic background of this
group of disorders.
Safety and Glycemic Outcomes With a Tubeless Automated Insulin Delivery System in Very Young Children With Type 1 Diabetes: A Single-Arm Multicenter Clinical Trial
Authors: Sherr Jennifer L. , Bode Bruce W. , Forlenza Gregory P. , Laffel Lori M. , Schoelwer Melissa J. , Buckingham Bruce A. , Criego Amy B. , DeSalvo Daniel J. , MacLeish Sarah A. , Hansen David W. , Ly Trang T. ,   for the Omnipod 5 in Preschoolers Study Group:, Sherr Jennifer L. , Weyman Kate , Tichy Eileen , VanName Michelle , Brei Michelle , Zgorski Melinda , Steffen Amy , Carria Lori , Bode Bruce W. , Busby Anna , Forlenza Gregory P. , Wadwa R. Paul , Slover Robert , Cobry Erin , Messer Laurel , Laffel Lori M. , Isganaitis Elvira , Ambler-Osborn Louise , Freiner Emily , Turcotte Christine , Volkening Lisa , Schoelwer Melissa , Brown Sue A. , Krauthause Katie , Emory Emma , Oliveri Mary , Buckingham Bruce A. , Ekhlaspour Laya , Kingman Ryan , Criego Amy B. , Schwartz Betsy L. , Gandrud Laura M. , Grieme Aimee , Hyatt Jamie , DeSalvo Daniel J. , McKay Siripoom , DeLaO Kylie , Villegas Carolina , MacLeish Sarah A. , Wood Jamie R. , Kaminski Beth A. , Casey Terri , Campbell Wendy , Behm Kim , Adams Ramon , Hansen David W. , Stone Sheri L. , Bzdick Suzan , Bulger Jane , Agostini Lynn , Doolittle Sarah , Kivilaid Kaisa , Kleve Krista , Ly Trang T. , Dumais Bonnie , Vienneau Todd , Huyett Lauren M. , Lee Joon Bok , O’Connor Jason , Benjamin Eric
Published: June 2022

OBJECTIVE

Very young children with type 1 diabetes often struggle to achieve glycemic targets, putting them at risk for long-term complications and creating an immense management burden for caregivers. We conducted the first evaluation of the Omnipod 5 Automated Insulin Delivery System in this population.

RESEARCH DESIGN AND METHODS

A total of 80 children aged 2.0–5.9 years used the investigational system in a single-arm study for 13 weeks following 14 days of baseline data collection with their usual therapy.

RESULTS

There were no episodes of severe hypoglycemia or diabetic ketoacidosis. By study end, HbA1c decreased by 0.55% (6.0 mmol/mol) (P < 0.0001). Time with sensor glucose levels in target range 70–180 mg/dL increased by 10.9%, or 2.6 h/day (P < 0.0001), while time with levels <70 mg/dL declined by median 0.27% (P = 0.0204).

CONCLUSIONS

Use of the automated insulin delivery system was safe, and participants experienced improved glycemic measures and reduced hypoglycemia during the study phase compared with baseline.
Risk Assessment for Electricity Generation Management Process with SWARA Based Fuzzy TOPSIS Method
Authors: KARAMOLLAOĞLU Hamdullah , YÜCEDAĞ İbrahim , DOGRU İbrahim
Published: June 2022

In the successful maintenance of electricity generation management processes in power generation plants, it is of great importance to determine the risks that may arise during the operation of the relevant processes, take measures to minimize these risks, and take the necessary actions. In this study, common risks in the electricity generation management process in HEPPs were identified and these risks were rated by experts (decision-makers) within each power plant itself. Since this rating is made by the experts of each power plant, the impact and probability values of the same risk may differ, and accordingly, different risk levels may arise for the same risk. In the study, the SWARA method was used to compare the risk levels of common risks in the electricity generation process in different power plants and calculate the final weight values of the related risks. As a result of the measures determined for each risk in the electricity generation management processes in the power plants and the actions taken for these measures, it was determined whether the relevant risks were reduced to acceptable levels by looking at the results of the internal audits. In the internal audits, the performance of HEPPs in eliminating the related risks is evaluated with fuzzy expressions separately for each risk. The risk weight values obtained by the SWARA method and the fuzzy expressions obtained as a result of the risk assessment were analyzed with the Fuzzy TOPSIS method, and the performance values of the power plants in eliminating the risks were calculated, then the performance ranking was made in the light of these values.
Adaptive analysis of multistage down-hole throttling and optimization design of process parameters in Sulige gas field
Authors: Yijun W. , Wu Y. , Zheng X. , Li Y. , Lu X. , Liu C. , Lu X.
Published: June 2022

The Sulige Gas Field mainly adopts down-hole throttling production technology. For gas Wells with high bottom-hole pressure and productivity and low pressure drop in the testing process, it is difficult to reduce the wellhead pressure to the ideal value by installing a single-stage down-hole throttle, which cannot meet the needs of existing middle and low-pressure gas gathering technology in Sulige Gas field. Therefore, it is proposed to adopt down-hole multi-stage throttling technology, which not only makes full use of the residual pressure and heat of the well bore, but also ensures the safety of the surface gathering and transportation process system and the normal production of gas wells. In this paper, the optimization design method and theory for the technological parameters of the down-hole multi-stage throttling system of gas wells are established. According to the constraint of low-pressure gas collection mode in a temperature and pressure of wellhead safety to determine the number of down-hole choke and the process parameters. Discuss the applied conditions of down-hole multi-stage throttling, and provide theoretical support for the selection of the down-hole choke technology of the Sulige gas well and the safe and stable production of the gas well. It has important guiding significance for gas field quality and efficiency improvement and fine management.
Use of phosphate silicate corrosion inhibitor in the treatment of make-up water for full internal hot water recirculation systems of apartment buildings in St. Petersburg
Authors:   «Mosslein RUS» company, Koptev A. V. , Baruzdin R. Eh. ,   Saint Petersburg State University of Architecture and Civil Engineering, Rukobratsky N. I. ,   Saint Petersburg State University of Architecture and Civil Engineering
Published: June 2022

The paper presents the results of technological research on the use of phosphate-silicate corrosion inhibitor for processing the make-up water of a full internal hot water recirculation system of apartment buildings in St. Petersburg. The inhibitor stops the process of corrosion of the inner surface of pipelines and protects them from deposits. With continuous dosing of this inhibitor at a dose of 15-20 mg/dm3 after 1-3 months from the beginning of its use, the quality of hot water according to organoleptic indicators, the content of total iron and zinc meets the current regulatory requirements. A break in the dosing of the inhibitor for up to one month and no more than five months does not lead to the deterioration in the quality of hot water.
The use of ammonia as motor fuel for vehicles operating in the Arctic region
Authors:   Saint Petersburg State University of Architecture and Civil Engineering, Vorobyov S. A. , Nikiforov O. A. ,   Saint Petersburg State University of Architecture and Civil Engineering, Abyzov I. T. ,   Saint Petersburg State University of Architecture and Civil Engineering
Published: June 2022

The article deals with the issue of using ammonia as fuel for vehicles operating in the Arctic region. A comparative analysis of various types of hydrogen fuels has been carried out. The prospects for the use of ammonia as a hydrogen carrier on board a vehicle have been determined. A power supply system for a diesel engine based on the decomposition of ammonia with the subsequent addition of hydrogen as an additive to the main fuel is proposed.
Comparative analysis of assessing natural vibration frequencies of rectangular panels with freely pinched edges
Authors:   Admiral Makarov State University of Maritime and Inland Shipping, Sukhoterin M. V. , Maslennikov A. M. ,   Saint Petersburg State University of Architecture and Civil Engineering, Rasputina E. I. ,   Admiral Makarov State University of Maritime and Inland Shipping, Voytko I. V. ,   Admiral Makarov State University of Maritime and Inland Shipping
Published: June 2022

An iterative method for assessing the frequency spectrum of free vibrations of rectangular panels with different support conditions in combination with the parameter enumeration method is proposed. Two hyperbolo-trigonometric series on two coordinates with indeterminate coefficients containing the desired frequency of free vibrations as a parameter are taken as a basis. The obtained natural frequencies and waveforms are compared with the results provided by other authors, and are presented very fully in tabular form, the accuracy of calculations and methods are analyzed.
Pengaruh Atribut Produk dan Harga Terhadap Brand Switching Produk Smartphone Samsung Ke Merek Lain
Authors: Atifah Murni , Rahmidani Rose
Published: June 2022

The purpose of this study was to determine the effect of product attributes and price on brand switching on Samsung smartphone products at Padang State University. This research used causative form.The population in this research were students of State University of Padang. The Number of samples were decided base on William Cochran's. As many as 100 people and were chosen by using non probability sampling method and purposive sampling technic.Data were used is primer data were provided through questionnaire shared to students of State University of Padang based on predetermined criteria. Analysis method was used is multiple regression by using spss 26. The results showed that (1) product attributes had a significant effect on brand switching of Samsung smartphone products to other brands, (2) price had a significant effect on brand switching of Samsung smartphone products to other brands, (3) product attributes and prices had a significant effect on brand switching products Samsung smartphones to other brands. Keywords : product attributes, price, brand switching
Problem-based learning in mathematics learning to improve reflective thinking skills and self-regulated learning
Authors: Yuni Yatha , Kusuma Arie Purwa , Huda Nurul
Published: June 2022

This research was aimed to determine the effectiveness of the Problem-Based Learning (PBL) model in mathematics learning on students' reflective thinking skills and self-regulated learning. The researchers employed the quantitative-qualitative method. The quantitative data was obtained through pretest and posttest, and qualitative data were obtained through interviews with three students selected using a purposive random sampling technique. The research subjects were selected using the accidental sampling technique because it was still in the new normal era of the COVID-19 pandemic. The subjects consisted of 33 eighth-grade students. The data was collected using test instruments and questionnaires. Furthermore, the data was tested using the independent sample t-test. This research found three results. First, there was a significant increase in reflective and self-regulated thinking skills through the application of the PBL model. Second, based on the t-test, there was a reflective thinking skills difference between pretest and posttest, with a higher score was found in the posttest. Third, there was no self-regulated learning difference between the pretest and posttest.
DIAGNOSING THE CHILD’S READINESS FOR MATHEMATICAL EDUCATION
Authors: Skibska Joanna
Published: June 2022

The following text concentrates on the readiness of a six–year–old child to learn mathematics. It presents brain organization of using numbers, paying special attention to existence of special network of nerve connections responsible for capturing changes in number, comparing sets of numbers and ordering numbers according to their physical and numerical size. The author com-pares the terms of readiness and maturity to learn mathematics, indicating their mutual relations, as well as presents available tools that serve estimating a child’s mathematical skills. Furthermore, she also discusses the researchers conducted on the group of six–year–olds in the scope of their maturity to learn mathematics in selected aspects.
MILITARY DISCOURSE AND PECULIARITIES OF ITS TRANSLATION
Authors: Korolova Tetiana , Sorich Rostyslav , Aleksandrova Olga
Published: June 2022

This article considers the concept and essence of the phenomenon of military discourse, reveals its structural features. The author focuses on the peculiarities of the functioning of military terms in the English military discourse, analyzes the general features of the translation of military discourse. The main translation transformations in the translation of military discourse were studied; the specifics of the transformation of English naval and air terminology in the Ukrainian translation were researched.
After analyzing the terminological units in the sample of 230 cases of translation transformations, we can conclude that the most frequent type of translation transformation of military terminology from English into Ukrainian are the use of lexical translation transformations, in particular, calque (26 cases, or 11.3 %), transliteration (20 cases, or 8.7 %), lexical-semantic substitutions (52 cases, or 22.6 %), concretization of meaning (26 cases, or 11.3 %), generalization of meaning (16 cases, or 7 %), modulation (32 cases, or 13.9 %).
Regarding grammatical transformations in the translation of military texts, the frequency of their use is as follows: grammatical substitutions (6 cases, or 2.6 %), sentence fragmentation (5 cases, or 2.2 %), sentence integration (3 cases, or 1.3 %), permutations (12 cases, or 5.2 %), zero translation (16 cases, or 7 %).
Also, for the translation of military texts were used such translation methods as half-calque (2 cases, or 0.9 %); interpretation (3 cases, or 1.3 %); elimination (4 cases, or 1.7 %); explication (7 cases, or 3 %). As a rule, foreign terms have corresponding equivalents in the language of translation, therefore such receptions, as synonymous substitutions, descriptive translation, are used only in those cases when in the language of translation, the corresponding term is absent.
COMPOSITIONAL AND SPEECH FRAMES OF ENGLISH ADVERTISING AND INFORMATION TEXTS AND THEIR IMPLEMENTATION IN UKRAINIAN TRANSLATION
Authors: Popova Oleksandra , Savaliuk Iryna
Published: June 2022

The article is devoted to the study of the peculiarities of the reproduction of frames of English advertising and informational texts in the Ukrainian language. The relevance of the work is due to the urgent need to consider the specifics of the translation of English-language advertising texts, and the importance of reproduction in the translation of compositional and informational advertising frames. The aim of the study is a theoretical and practical study of the specifics of the implementation of compositional-speech frames of English advertising and informational texts in Ukrainian. Scientific novelty lies in the identification of the specifics of the translation of a number of frames in the advertising discourse, focused on certain age and gender categories of consumers. Advertising discourse is a communicative structure, the frame strategies of which functioning in the communicative space of advertising are determined by the complex interaction of frames of various slots. As a result of the research, the author comes to the conclusion that the purpose of the translator is to use all knowledge of the theoretical foundations of translation to convey the communicative function of the original and to comply with such criteria of the advertising text as compactness, laconism, accuracy, and concreteness. Translated ad copy is a means that allows overseas companies to gain visibility and build a reputation with buyers in other countries. The success of an advertising campaign directly depends on the quality of its translation, which is considered a kind of art and requires from the translator not only good knowledge of linguistic and stylistic skills, but also such qualities as creativity, accuracy, awareness of the cultural traditions of the target language. During the analysis, we determined that a prerequisite for translation is the selection of appropriate means to convey not only the very meaning of the advertising message, but its expressive, gender, age and functional characteristics.
PECULIARITIES OF TRANSLATING COLOR NAMES FROM ENGLISH INTO UKRAINIAN
Authors: Stoianova Tetiana , Kotsabenko Olena , Kylymnyk Olha
Published: June 2022

The article has been devoted to the description of colour names in the aspect of their functioning in belles-lettres style and their adequate rendering in artisic translation from English into Ukrainian. Nominations of colour have been investigated as linguistic units with semantic sustainability, high adaptiveness, and variability depending on the author’s cultural background and experience. Colour names have been studied as linguistic and cultural symbols, charged by certain mentality and expressiveness. The topic of the research is up-to-date in the paradigm of the functional-communicative approach to translation. In the focus of the research there are various types of colour names and the peculiarities of rendering English colour names in Ukrainian translation. The research is done on the basis of the long short stories “Dandelion Wine” by Ray Bradbury and “The Great Gatsby” by Francis Scott Fitzerald. The colour names’ semantics is realized in belles-lettres texts on linguistic, extralinguistic and cultural levels. It has been proved that colour names often have symbolic meaning in artistic texts. Being associated with the author’s mentality and world outlook, symbols are relevant for artistic translation in general. Thus, it has been resumed that adequate rendering of colour names is essential for faithful translation. To preserve scientific specificity of the source text, in particular in the aspect of redering the semantics of colour names, translators employ proper translation operations according to the chosen translation strategy of the communicatively relevant translation. Translation transformations are the most widely distributed among other operations at work. The perspective is seen in further investigation of colour names on the different linguistic material and in other Indo-European languages.
Activation of proteinase-activated receptor-2 (PAR-2) simultaneously induces interleukin 8 (IL-8) and suppresses monocyte chemoattractant protein-1 (MCP-1) in HaCaT cells
Authors: Murakami Yoshinobu , Azuma Seisho , Baba Kimiye , Taniguchi Masahiko , Furukawa Fukumi
Published: June 2022

Allergic diseases are currently considered diseases of excessive type 2 inflammation created by orchestration between the innate and acquired immune systems. Since pattern recognition receptors (PRRs) are present in epidermal keratinocytes, it is noteworthy that aggravating factors of allergic diseases act directly on keratinocytes via PRRs. To investigate the relationship between the activation of PRRs and inflammation, we stimulated a keratinocyte cell line (HaCaT cells) with agonists against proteinase-activated receptor-2 (PAR-2), Toll-like receptor (TLR)2, and TLR4, alone or in combination, and we evaluated the changes in inflammatory cytokines and chemokines. Activation of TLR2 or TLR4 alone induced interleukin 6 (IL-6), IL-8, and monocyte chemoattractant protein-1 (MCP-1) in an agonist concentration-dependent manner. Simultaneous activation of TLR2 and TLR4 induced IL-8 synergistically, MCP-1 in an additive trend, and IL-6 weakly but synergistically. PAR-2 activation of HaCaT cells induced IL-6 and IL-8 but suppressed MCP-1 in an agonist concentration-dependent manner. The enhancement of IL-8 and the suppression of MCP-1 by PAR-2 activation were both neutralized by the PAR-2 antagonist AZ3451, supporting the possibility that PAR-2 activation simultaneously induces the following opposing effects in inflammation: enhancement of IL-8 and suppression of MCP-1. The nuclear factor-κB (NF-κB) pathway inhibitor BAY 11-7082 neutralized the induction of IL-8 but not the suppression of MCP-1 by PAR-2 activation, indicating that PAR-2 activation induces activation of the NF-κB pathway, and that the suppression of MCP-1 by PAR-2 activation is not related to the NF-κB pathway.