bluuebunny/crossref_metadata_2025 huggingface dataset:
Becoming Healthier without Paying More? Experimental Evidence from the Impact of Multiple Traffic Lights on Chinese College Students
Authors: Lin Jing , Wang Tingyu , Lin Wen
Published: July 2024

The prevalence of overweight and obesity among Chinese residents has become a pressing public health concern. The UK Multiple Traffic Light labeling system, known for its user-friendly design, has demonstrated success in promoting healthier food choices. This paper presents novel findings from a randomized controlled experiment assessing the impact of traffic light labeling on Chinese consumers’ food choices. Results indicate that the label significantly reduces the intake of calories, fat, carbohydrates, and sodium without increasing the economic costs of food choices. This study contributes empirical evidence to the effectiveness of traffic light labeling in China, with implications for the country’s approach to front-of-pack nutrition labeling.
Species Composition of a Small Mammal Community and Prevalence of Echinococcus spp. in the Alpine Pastoral Area of the Eastern Tibetan Plateau
Authors: Zheng Jia-Xin , Sun Xiao-Hui , Wei Xu , Wang Gang , Yuan Chang-Qing , Weng Xiao-Dong , Zuo Qing-Qiu , Liu Jia-Yu , Mu Zhi-Qiang , Mao Tian-Ci , Ding You-Zhong , Wang Xiao-Ming , Wang Xu , Wang Zheng-Huan
Published: July 2024

We aimed to investigate the species composition of a small mammal community and the prevalence of Echinococcus spp. in a typical endemic area of the Tibetan Plateau. One pika and five rodent species were identified based on the morphological characteristics of 1278 small mammal specimens collected during 2014–2019. Detection of Echinococcus DNA in tissue samples from small mammal specimens revealed that Ochotona curzoniae (pika, total prevalence: 6.02%, 26/432), Neodon fuscus (5.91%, 38/643), N. leucurus (2.50%, 3/120), and Alexandromys limnophilus (21.74%, 10/46) were infected by both E. multilocularis and E. shiquicus; Cricetulus longicaudatus (16.67%, 1/6) was infected by E. shiquicus; and no infection was detected in N. irene (0/15). Neodon fuscus and O. curzoniae were the two most abundant small mammal species. There was no significant difference in the prevalence of pika and the overall rodent species assemblage (6.26%, 53/846); however, the larger rodent populations suggested that more attention should be paid to their role in the transmission of echinococcosis in the wildlife reservoir, which has long been underestimated. Moreover, although DNA barcoding provides a more efficient method than traditional morphological methods for identifying large numbers of small mammal samples, commonly used barcodes failed to distinguish the three Neodon species in this study. The close genetic relationships between these species suggest the need to develop more powerful molecular taxonomic tools.
Oral Treatment with the Pectin Fibre Obtained from Yellow Passion Fruit Peels Worsens Sepsis Outcome in Mice by Affecting the Intestinal Barrier
Authors: da Silveira Bruna C. , da Silva Platner Fernanda , da Rosa Liza B. , Silva Matheus L. C. , da Silva Karien S. , de Oliveira Natalia M. T. , Moffa Eduardo B. , Silva Karinny F. , Lima-Neto Lídio G. , Maria-Ferreira Daniele , Cordeiro Lucimara M. C. , Gois Marcelo B. , Fernandes Elizabeth S.
Published: July 2024

The biological activities of plant-derived soluble dietary fibres (SDFs) have been widely investigated. Pectin from yellow passion fruit (YPF-peSDF) peels was suggested as a protective macromolecule in ulcers and colitis due to its antioxidant and anti-inflammatory properties. Sepsis has high mortality and morbidity and is characterised by inflammatory and oxidative stress imbalances. Evidence suggests that pectins may aid sepsis treatment; however, the effects of YPF-peSDF on sepsis remain unclear. Herein, polymicrobial sepsis was induced by cecal-ligation and puncture in mice treated with YPF-peSDF (1 and 10 mg/kg; gavage). YPF-peSDF accelerated mortality, reaching 100% in 24 h. Inflammation was present in the colons and small intestines (SI) of both vehicle- and fibre-treated mice. Although crypt depth and width, and villus height were preserved in the SI of septic mice administered YPF-peSDF, they exhibited exacerbated muscle layer atrophy and mucosa and submucosa hypertrophy, along with shortened enterocytes. Larger crypts and shorter enterocytes were noted in their colons in comparison with vehicle-controls. YPF-peSDF also reduced inflammatory cell numbers and exacerbated IL-6 levels in peritoneal lavage fluid (PELF) samples. YPF-peSDF modulated SI but not colon cytokines. Lipoperoxidation and antioxidant capacity levels were attenuated in PELF samples. Overall, in contrast to previous evidence, YPF-peSDF worsened polymicrobial sepsis outcomes in mice.
Structure-Based Identification of Novel Histone Deacetylase 4 (HDAC4) Inhibitors
Authors: Agarwal Rupesh , Pattarawat Pawat , Duff Michael R. , Wang Hwa-Chain Robert , Baudry Jerome , Smith Jeremy C.
Published: July 2024

Histone deacetylases (HDACs) are important cancer drug targets. Existing FDA-approved drugs target the catalytic pocket of HDACs, which is conserved across subfamilies (classes) of HDAC. However, engineering specificity is an important goal. Herein, we use molecular modeling approaches to identify and target potential novel pockets specific to Class IIA HDAC-HDAC4 at the interface between HDAC4 and the transcriptional corepressor component protein NCoR. These pockets were screened using an ensemble docking approach combined with consensus scoring to identify compounds with a different binding mechanism than the currently known HDAC modulators. Binding was compared in experimental assays between HDAC4 and HDAC3, which belong to a different family of HDACs. HDAC4 was significantly inhibited by compound 88402 but not HDAC3. Two other compounds (67436 and 134199) had IC50 values in the low micromolar range for both HDACs, which is comparable to the known inhibitor of HDAC4, SAHA (Vorinostat). However, both of these compounds were significantly weaker inhibitors of HDAC3 than SAHA and thus more selective, albeit to a limited extent. Five compounds exhibited activity on human breast carcinoma and/or urothelial carcinoma cell lines. The present result suggests potential mechanistic and chemical approaches for developing selective HDAC4 modulators.
Synthesis of Nitrostyrylthiazolidine-2,4-dione Derivatives Displaying Antileishmanial Potential
Authors: Khoumeri Omar , Hutter Sébastien , Primas Nicolas , Castera-Ducros Caroline , Carvalho Sandra , Wyllie Susan , Efrit Mohamed Lotfi , Fayolle Dimitri , Since Marc , Vanelle Patrice , Verhaeghe Pierre , Azas Nadine , El-Kashef Hussein
Published: July 2024

A series of 61 thiazolidine-2,4-diones bearing a styryl group at position 5 was synthesized in 2–5 steps and their structure was proved by elemental and spectral analyses. The compounds obtained were evaluated in vitro against the promastigote stage of the kinetoplastid parasite Leishmania infantum and the human HepG2 cell line, to determine selectivity indices and to compare their activities with those of antileishmanial reference drugs. The study of structure–activity relationships indicated the potential of some derivatives bearing a nitro group on the phenyl ring, especially when located at the meta position. Thus, among the tested series, compound 14c appeared as a hit compound with good antileishmanial activity (EC50 = 7 µM) and low cytotoxicity against both the hepatic HepG2 and macrophage THP-1 human cell lines (CC50 = 101 and 121 µM, respectively), leading to good selectivity indices (respectively, 14 and 17), in comparison with the reference antileishmanial drug compound miltefosine (EC50 = 3.3 µM, CC50 = 85 and 30 µM, SI = 26 and 9). Regarding its mechanism of action, among several possibilities, it was demonstrated that compound 14c is a prodrug bioactivated, predominantly by L. donovani nitroreductase 1, likely leading to the formation of cytotoxic metabolites that form covalent adducts in the parasite. Finally, compound 14c is lipophilic (measured CHI LogD7.7 = 2.85) but remains soluble in water (measured PBS solubility at pH7.4 = 16 µM), highlighting the antileishmanial potential of the nitrostyrylthiazolidine-2,4-dione scaffold.
Extended Release of Bupivacaine from Temperature-Responsive PNDJ Hydrogels Improves Postoperative Weight-Bearing in Rabbits Following Knee Surgery
Authors: Overstreet Derek J. , Zdrale Gabriel , McLaren Alex C.
Published: July 2024

Effective treatment of postoperative pain lasting for multiple days without opioids is an important clinical need. We previously reported analgesia lasting up to 96 h in a porcine soft tissue model of postoperative pain using SBG004, an extended-release formulation of bupivacaine based on the temperature-responsive polymer poly(N-isopropylacrylamide-co-dimethylbutyrolactone acrylamide-co-Jeffamine M-1000 acrylamide) [PNDJ]. Orthopaedic surgical sites such as the knee can involve complex sensory innervation which presents a distinct challenge to local anesthetic delivery. The purpose of this work was to evaluate the pharmacokinetics and efficacy of SBG004 in an orthopaedic surgical model in comparison to currently available local anesthetics. Pharmacokinetics following periarticular (PA) or intraarticular (IA) injection of SBG004 were compared against liposomal bupivacaine (Lip-Bupi) PA in New Zealand White rabbits (all doses 14.5 mg/kg). Analgesic efficacy of SBG004 (IA, PA, or IA + PA), three active comparators, and saline was evaluated following knee surgery in New Zealand White rabbits. Analgesia was assessed via weight-bearing on the operated limb during spontaneous large steps in video recordings. Systemic bupivacaine exposure lasted at least 7 days for SBG004 PA, 4 days for SBG004 IA, and 2 days for Lip-Bupi PA. In the analgesia study, weight-bearing in all active groups except SBG004 IA was more frequent versus saline through 8 h postoperatively (p < 0.05). Only SBG004 IA + PA resulted in a higher proportion of weight-bearing rabbits at 24 h versus saline (6/7 versus 2/10, p = 0.015). Analysis of pooled data from 24–72 h showed significantly greater frequency of weight-bearing in rabbits receiving SBG004 IA + PA (71%) versus saline (37%), ropivacaine cocktail (41%), and Lip-Bupi PA (36%). The results indicate that the release profile from SBG004 PA or IA coincides reasonably with the time course of postoperative pain, and SBG004 may produce longer duration of analgesia than local anesthetics currently used in knee surgery, including during the period of 24–72 h recognized as a target for extended-release local anesthetics.
Emerging Trends in the Treatment of Skin Disorders by Herbal Drugs: Traditional and Nanotechnological Approach
Authors: Agrawal Rutvi , Jurel Priyanka , Deshmukh Rohitas , Harwansh Ranjit Kumar , Garg Akash , Kumar Ashwini , Singh Sudarshan , Guru Ajay , Kumar Arun , Kumarasamy Vinoth
Published: July 2024

Since the earliest days, people have been employing herbal treatments extensively around the world. The development of phytochemical and phytopharmacological sciences has made it possible to understand the chemical composition and biological properties of a number of medicinal plant products. Due to certain challenges like large molecular weight and low bioavailability, some components of herbal extracts are not utilized for therapeutic purposes. It has been suggested that herbal medicine and nanotechnology can be combined to enhance the benefits of plant extracts by lowering dosage requirements and adverse effects and increasing therapeutic activity. Using nanotechnology, the active ingredient can be delivered in an adequate concentration and transported to the targeted site of action. Conventional therapy does not fulfill these requirements. This review focuses on different skin diseases and nanotechnology-based herbal medicines that have been utilized to treat them.
Development, Characterization, and Evaluation of Potential Systemic Toxicity of a Novel Oral Melatonin Formulation
Authors: Cheaburu-Yilmaz Catalina N. , Atmaca Kemal , Yilmaz Onur , Orhan Hilmi
Published: July 2024

The need to create safe materials for biomedical and pharmaceutical applications has become a significant driving force for the development of new systems. Therefore, a chitosan-coated copolymer of itaconic acid, acrylic acid, and N-vinyl caprolactam (IT-AA-NVC) was prepared by radical polymerization and subsequent coating via nanoprecipitation to give a system capable of sustained delivery of melatonin. Although melatonin brings undoubted benefits to the human body, aspects of the optimal dose, route, and time of administration for the obtaining of suitable treatment outcomes remain under discussion. The entrapment of melatonin in biocompatible polymeric systems can prevent its oxidation, decrease its toxicity, and provide an increased half-life, resulting in an enhanced pharmacokinetic profile with improved patient compliance. The structures of the biopolymer and conjugate were proven by FTIR, thermal properties were tested by DSC, and the morphologies were followed by SEM. The loading efficiency and in vitro release profile were studied by means of HPLC, and a delayed release profile with an initial burst was obtained. The potential systemic toxicity of the formulation was studied in vivo; a mild hepatotoxicity was observed following administration of the melatonin-loaded formulation to mice, both by histopathology and blood clinical biochemistry. Histopathology showed a mild nephrotoxicity as well; however, kidney clinical biochemistry did not support this.
Cationic Liposomes Carrying HPV16 E6-siRNA Inhibit the Proliferation, Migration, and Invasion of Cervical Cancer Cells
Authors: Sánchez-Meza Luz Victoria , Bello-Rios Ciresthel , Eloy Josimar O. , Gómez-Gómez Yazmín , Leyva-Vázquez Marco Antonio , Petrilli Raquel , Bernad-Bernad María Josefa , Lagunas-Martínez Alfredo , Medina Luis Alberto , Serrano-Bello Janeth , Organista-Nava Jorge , Illades-Aguiar Berenice
Published: July 2024

The E6 and E7 oncoproteins of high-risk types of human papillomavirus (HR-HPV) are crucial for the development of cervical cancer (CC). Small interfering RNAs (siRNAs) are explored as novel therapies that silence these oncogenes, but their clinical use is hampered by inefficient delivery systems. Modification (pegylation) with polyethylene glycol (PEG) of liposomal siRNA complexes (siRNA lipoplexes) may improve systemic stability. We studied the effect of siRNA targeting HPV16 E6, delivered via cationic liposomes (lipoplexes), on cellular processes in a cervical carcinoma cell line (CaSki) and its potential therapeutic use. Lipoplexes-PEG-HPV16 E6, composed of DOTAP, Chol, DOPE, and DSPE-PEG2000 were prepared. The results showed that pegylation (5% DSPE-PEG2000) provided stable siRNA protection, with a particle size of 86.42 ± 3.19 nm and a complexation efficiency of over 80%; the siRNA remained stable for 30 days. These lipoplexes significantly reduced HPV16 E6 protein levels and restored p53 protein expression, inhibiting carcinogenic processes such as proliferation by 25.74%, migration (95.7%), and cell invasion (97.8%) at concentrations of 20 nM, 200 nM, and 80 nM, respectively. In conclusion, cationic lipoplexes-PEG-HPV16 E6 show promise as siRNA carriers for silencing HPV16 E6 in CC.
Process-Induced Crystal Surface Anisotropy and the Impact on the Powder Properties of Odanacatib
Authors: Bade Isha , Karde Vikram , Schenck Luke , Solomos Marina , Figus Margaret , Chen Chienhung , Axnanda Stephanus , Heng Jerry Y. Y.
Published: July 2024

Crystalline active pharmaceutical ingredients with comparable size and surface area can demonstrate surface anisotropy induced during crystallization or downstream unit operations such as milling. To the extent that varying surface properties impacts bulk powder properties, the final drug product performance such as stability, dissolution rates, flowability, and dispersibility can be predicted by understanding surface properties such as surface chemistry, energetics, and wettability. Here, we investigate the surface properties of different batches of Odanacatib prepared through either jet milling or fast precipitation from various solvent systems, all of which meet the particle size specification established to ensure equivalent biopharmaceutical performance. This work highlights the use of orthogonal surface techniques such as Inverse Gas Chromatography (IGC), Brunauer–Emmett–Teller (BET) surface area, contact angle, and X-ray Photoelectron Spectroscopy (XPS) to demonstrate the effect of processing history on particle surface properties to explain differences in bulk powder properties.
Recent Advances in the Development of Hybrid Drugs
Authors: Morais Tânia S.
Published: July 2024

In the search for innovative, selective, effective, and safer treatment strategies, hybrid drugs have gained worldwide momentum [...]
A High-Precision Identification Method for Maize Leaf Diseases and Pests Based on LFMNet under Complex Backgrounds
Authors: Liu Jintao , He Chaoying , Jiang Yichu , Wang Mingfang , Ye Ziqing , He Mingfang
Published: July 2024

Maize, as one of the most important crops in the world, faces severe challenges from various diseases and pests. The timely and accurate identification of maize leaf diseases and pests is of great significance for ensuring agricultural production. Currently, the identification of maize leaf diseases and pests faces two key challenges: (1) In the actual process of identifying leaf diseases and pests, complex backgrounds can interfere with the identification effect. (2) The subtle features of diseases and pests are difficult to accurately extract. To address these challenges, this study proposes a maize leaf disease and pest identification model called LFMNet. Firstly, the localized multi-scale inverted residual convolutional block (LMSB) is proposed to perform preliminary down-sampling on the image, preserving important feature information for the subsequent extraction of fine disease and pest features in the model structure. Then, the feature localization bottleneck (FLB) is proposed to improve the model’s ability to focus on and locate disease and pest characteristics and to reduce interference from complex backgrounds. Subsequently, the multi-hop local-feature fusion architecture (MLFFA) is proposed, which effectively addresses the problem of extracting subtle features by enhancing the extraction and fusion of global and local disease and pest features in images. After training and testing on a dataset containing 19,451 images of maize leaf diseases and pests, the LFMNet model demonstrated excellent performance, with an average identification accuracy of 95.68%, a precision of 95.91%, a recall of 95.78%, and an F1 score of 95.83%. Compared to existing models, it exhibits significant advantages, offering robust technical support for the precise identification of maize diseases and pests.
Genome Assembly and Structural Variation Analysis of Luffa acutangula Provide Insights on Flowering Time and Ridge Development
Authors: Huang Aizheng , Feng Shuo , Ye Zhuole , Zhang Ting , Chen Shenglong , Chen Changming , Chen Shijun
Published: July 2024

Luffa spp. is an important worldwide cultivated vegetable and medicinal plant from the Cucurbitaceae family. In this study, we report a high-quality chromosome-level genome of the high-generation inbred line SG261 of Luffa acutangula. The genomic sequence was determined by PacBio long reads, Hi-C sequencing reads, and 10× Genomics sequencing, with an assembly size of 739.82 Mb, contig N50 of 18.38 Mb, and scaffold N50 of 56.08 Mb. The genome of L. acutangula SG261 was predicted to contain 27,312 protein-coding genes and 72.56% repetitive sequences, of which long terminal repeats (LTRs) were an important form of repetitive sequences, accounting for 67.84% of the genome. Phylogenetic analysis reveals that L. acutangula evolved later than Luffa cylindrica, and Luffa is closely related to Momodica charantia. Comparing the genome of L. acutangula SG261 and L. cylindrica with PacBio data, 67,128 high-quality structural variations (SVs) and 55,978 presence-absence variations (PAVs) were identified in SG261, resulting in 2424 and 1094 genes with variation in the CDS region, respectively, and there are 287 identical genes affected by two different structural variation analyses. In addition, we found that the transcription factor FY (FLOWERING LOCUS Y) families had a large expansion in L. acutangula SG261 (flowering in the morning) compared to L. cylindrica (flowering in the afternoon), which may result in the early flowering time in L. acutangula SG261. This study provides valuable reference for the breeding of and pan-genome research into Luffa species.
Unearthing Grape Heritage: Morphological Relationships between Late Bronze–Iron Age Grape Pips and Modern Cultivars
Authors: Ucchesu Mariano , Depalmas Anna , Sarigu Marco , Gardiman Massimo , Lallai Andrea , Meggio Franco , Usai Alessandro , Bacchetta Gianluigi
Published: July 2024

The grapevine was one of the earliest domesticated fruit crops and has been cultivated since ancient times. It is considered one of the most important fruit crops worldwide for wine and table grape production. The current grape varieties are the outcome of prolonged selection initiated during the domestication process of their wild relative. Recent genetic studies have shed light on the origins of the modern domestic grapevine in western Europe, suggesting that its origin stems from the introgression between eastern domestic grapes and western wild grapes. However, the origin of ancient grapevines remains largely unexplored. In this study, we conducted an extensive analysis of 2228 well-preserved waterlogged archaeological grape pips from two sites in Sardinia (Italy), dated to the Late Bronze Age (ca. 1300–1100 BC) and the Iron Age (4th and 3rd centuries BC). Using morphometrics and linear discriminant analyses, we compared the archaeological grape pips with modern reference collections to differentiate between wild and domestic grape types and to investigate similarities with 330 modern cultivars. Grape pips from the Late Bronze Age displayed a high percentage of similarity with domesticated grapevines, with a small percentage assigned to wild ones, while the majority of grape pips from the Iron Age were classified as domestic. Discriminant analyses revealed that both white and red grape varieties were cultivated during the Late Bronze and Iron Ages, suggesting a high level of diversification in grape cultivation. Furthermore, a high percentage of archaeological grape pips from both periods showed strong similarities with modern cultivars from the Caucasus and Balkans. This suggests that the great diversity of grapevines present in Sardinia could result from interbreeding between western Asian cultivars and local grapevines that began in the Late Bronze Age. Additionally, a substantial proportion of archaeological grape pips exhibited similar morphometric characteristics to two important Mediterranean grape cultivars: “Muscat à petits grains blancs” and “Garnacha”.
Interpreting Digital Transformation from a Psychological Perspective: A Case Study of the Oil and Gas Industry
Authors: Zhang Jiaming , Yang Yan , Zhang Yundong , Liu Shuaiqi , Qiu Maoxin , Zhang Huazhen
Published: July 2024

This article addresses the problem statement and objective by exploring the necessity, scope, and execution of digital transformation in the oil and gas industry from a psychological perspective. It highlights the cognitive barriers faced by non-ICT professionals, which are often overlooked in traditional approaches. The study integrates case studies and empirical evidence from a mixed-methods approach, including qualitative interviews with industry experts and quantitative surveys among employees, to provide a comprehensive understanding of the transformation process. The research emphasizes the integration of psychological theories with practical digital transformation strategies, illustrating key obstacles and solutions. By adopting a holistic approach that incorporates both technological advancements and psychological insights, the study aims to enhance the effectiveness and sustainability of digital transformation efforts. Major contributions include identifying cognitive barriers, proposing solutions to overcome these barriers, and presenting real-world applications that demonstrate the successful merging of psychological insights and digital strategies in the oil and gas sector.
Religious and Spiritual Communities Must Adapt or Die: Surviving and Thriving during Challenging Contemporary Times
Authors: Plante Thomas G.
Published: July 2024

Current trends within both religious and secular communities suggest that contemporary times mean that people spend more time alone than with others. Community engagement in general has been declining, while religious and spiritual community engagement in particular has dropped off significantly in recent decades, and most especially following the COVID-19 global pandemic. Although humans are social beings and benefit from community engagement, we tend to avoid or minimize our affiliations and associations, including our religious and spiritual ones today. Religious and spiritual communities must adapt to changing times or risk becoming irrelevant, diminishing further, and losing their sustainability to continue with their activities and services. Religious communities might wish to consider the best state-of-the-art evidence-based practices to engage their members, as well as appeal to those who might be interested in joining with them. There are many mental and physical health benefits to active engagement with spiritual religious practices and communities. The world could use more rather than less community engagement, including religious and spiritual engagement, during our challenging contemporary times.
Unraveling Prapañca: A Yogācāra Examination of Consciousness, Language, and Liberation in the Laṅkāvatāra Sūtra
Authors: Cai Tiantian
Published: July 2024

In Yogācāra epistemology, the term prapañca refers to various dimensions of the cognitive process in aspects ranging from consciousness, language formation, the conceptualization of subject–object duality, mental defilements, and ignorance. Given that the Laṅkāvatāra Sūtra conveys the richness of early tenets for both the Yogācāra and Madhyamaka traditions, an investigation of the meaning and discourse context of prapañca is a necessity. This paper conducts a contextual examination of the word prapañca, primarily addressing (1) a range of meanings, (2) possible characteristics, (3) conditions and consequences, especially the associations with the conceptualization (vikalpa) process, and (4) the significance of the elimination of prapañca that the corresponding dialogue implies. This paper finds that prapañca is associated with dualistic conceptualization and the evolution of consciousness within saṃsāra. It shows some qualities of the beginningless conceptual structure of saṃsāric conditioned negativity and is related to language formation. As the discourse in Laṅka adduces it as the root of suffering, liberation from it is a prerequisite for reaching enlightenment and achieving the state of Buddhahood.
Unveiling the Inner World: Exploring Emotional Intelligence, Faith, and Time Perspective among Italian Nuns
Authors: Collazos Ugarte Cecilia , Crea Giuseppe , Swaminathan Joseph Jeyaraj
Published: July 2024

The aim of this study was to verify whether emotional intelligence and intrinsic religious orientation have a positive influence on a balanced time perspective (BTP) in the lives of Italian consecrated women. A positive, balanced time perspective, together with the ability to recognize one’s own emotions and those of others, is integral to people’s experience of religiosity in their lives. In this way, a balanced time perspective can open the experience of religiosity, contributing to a better world, along with all those who are engaged in a religious sentiment that is no longer limited to single segments of self-interest. In this study, we provided evidence that religious beliefs (not just participation in corporate religious life) can provide an alternative source of understanding emotions and perceiving time, for the religious people who live their consecrated life together. We tested whether this phenomenon was specific to the potential associations between various aspects of religious belief, emotional intelligence, and time perspective. This research was conducted on a sample of 283 Italian nuns, and it was verified that both emotional intelligence and intrinsic religiosity contribute significantly to a BTP. Furthermore, the fact that emotional intelligence is mediated by intrinsic religious orientation increases the benefits of emotional intelligence on the BTP of Italian nuns. Altogether, our results suggest that religiosity is linked to a balanced temporal profile and to a positive way of understanding emotions. More specifically, the pattern of relationships between religion, emotions, and time can influence and deepen both the individual and collective understanding of humanity among these religious women and create space for mutual engagement despite obvious differences. These results are in line with the requisites of Public Theology, as they allow us to specify selectively the developments on a more secure and empirical basis of how religiosity can affect the life of people, by exposing the submerged theological assumptions that characterize the internal beliefs of religiosity. Moreover, the research data indicate that the deep aspects of religiosity influence greatly the day-to-day living of religious women. This practical influence of religiosity confirms the urgency of opening up theological reflection in the public sphere of life. In fact, as long as the religiosity of the nuns is not reduced to private practice, theological reflection will also be opened to its public significance in the different fields of their apostolic mission.
Assyrian Chronology and Ideology of Kingship: The Impact on Biblical Historiography and Religion
Authors: Derstine Philip
Published: July 2024

Studies since 2005 have raised doubts about the Assyrian King List’s (AKL) intention and ability to measure absolute time. If telescoping of time occurred, it would be difficult to detect during periods when royal annals were scant. The best way to detect discontinuity in the AKL is by comparison with contemporary king lists, such as one constructed from 1–2 Kings regnal formulas. If the AKL conflates time, an assessment of the plausibility of historical scenarios resulting from different timeframes allows for discrimination between one timeline or another. Israel and Judah’s interlocking chronological systems make a comparison with the Neo-Assyrian timeline possible but contain 44 more years than the timeline implied by the AKL and Assyrian Eponym Canon. By narrowing the window of time within which a deficit in the Neo-Assyrian canons may have occurred, possible reasons for missing years in the consensus chronology present themselves. This investigation concludes that Assyria sought to maintain the legitimacy of the institution of kingship during a protracted period of unacceptable or anomalous authority. Concerns surrounding the continuity of kingship would have dictated the final form of the Assyrian King List/Assyrian Eponym Canon. Using Divided Kingdom regnal data, a revision of the historical timeline is proposed that aligns archaeological, radiocarbon, biblical, and Assyrian data.
Is the Muslim Brotherhood a Sect?
Authors: Menshawy Mustafa
Published: July 2024

This article proposes the novel understanding of the Egyptian Muslim Brotherhood as a sect, going against the grain of the existing literature, which posits it as a political group, a social movement, or a religious movement (or some combination of all of the above). The sectarianisation occurs within the group via ideological build-up, organisational tactics, and internal socialisation of behaviour. The group is also a sect by constituting its unique identity in opposition to external actors. To make the argument, the analysis draws on the statements of key figures within the movement’s history, such as its founder Hasan al-Banna, as well as a range of interviews with current and ex-members. My argument has two main consequences for our understanding of sectarianism in general and the Brotherhood in particular. First, sectarianism is a process of sectarianisation that operates beyond the state and at lower levels, such as groups and individuals. Second, the Brotherhood is not a mere victim of the sectarianising practices of the state. Its sectarianisation is partly of its own making.
Cultural Governmentality and the Momentum of Religious Rituals in Taiwan: A Religio-Cultural Evolution of Popular Religion
Authors: Chi Wei-Hsian
Published: July 2024

Taiwanese popular religion has encountered significant challenges due to the sweeping social changes accompanying the modernization of Taiwanese society. This paper seeks to uncover the distinct dynamics at play, focusing on the transformation of procession troupes, which are an essential part of important religious events known as divine processions: a common collective ritual among local worship communities in Taiwan. Two pivotal external forces have surfaced, providing traditional procession troupes with opportunities for revitalization amidst what had been waning relevance. The first is the narrative of cultural heritage advanced by the public sector, and the second is the commercialization trend of the troupe market. The interplay of ‘cultural coding’ and ‘commercial coding’ has emerged as a key factor in maintaining the relevance and operations of traditional procession troupes in contemporary times. The analysis in this paper reveals that the modern evolution of popular religion is grounded not in its religious core but rather in the cultural significance of its rituals amidst the broader process of ‘culturalization of religion’.
Travelling Thomas: Slave Trade and Missionary Travel in the Acts of Thomas
Authors: Kartzow Marianne Bjelland
Published: July 2024

The Acts of Thomas is a long, rich, and fascinating narrative about the Apostle Thomas who was forced to travel to India as a missionary. When Thomas hesitates to go, his master Jesus literally sells him as a slave to an Indian merchant. Like other Apocryphal Acts, the Acts of Thomas revolves around the apostolic figure battling both human and demonic adversaries. Celibacy is central, although familiar narrative elements from ancient romances and novels are also present. On his way, Thomas sings, prays, teaches, heals, converts, and baptizes. His travel follows open trade routes in the ancient world, by land and by sea. He participates in various social events like parties, weddings, and family celebrations. His own status as a foreign slave/apostle, with a strange religion, is negotiated and contested: Sometimes he is treated like a foreign slave, suffering violence and harassment. On other occasions, his exotic strangeness in language and religion gives him access to royal palaces and influential men and women. By examining the role played by slavery in initiating this travel, as well as various intersections of religion and gender in the overall narrative, this article explores the Acts of Thomas to draw a more nuanced picture of travel in the ancient world.
Hydrogen in Energy Transition: The Problem of Economic Efficiency, Environmental Safety, and Technological Readiness of Transportation and Storage
Authors: Revinova Svetlana , Lazanyuk Inna , Gabrielyan Bella , Shahinyan Tatevik , Hakobyan Yevgenya
Published: July 2024

The circular economy and the clean-energy transition are inextricably linked and interdependent. One of the most important areas of the energy transition is the development of hydrogen energy. This study aims to review and systematize the data available in the literature on the environmental and economic parameters of hydrogen storage and transportation technologies (both mature and at high technological readiness levels). The study concluded that salt caverns and pipeline transportation are the most promising methods of hydrogen storage and transportation today in terms of a combination of all parameters. These methods are the most competitive in terms of price, especially when transporting hydrogen over short distances. Thus, the average price of storage will be 0.35 USD/kg, and transportation at a distance of up to 100 km is 0.3 USD/kg. Hydrogen storage underground in a gaseous state and its transportation by pipelines have the least consequences for the environment: emissions and leaks are insignificant, and there is no environmental pollution. The study identifies these methods as particularly viable given their lower environmental impact and potential for seamless integration into existing energy systems, therefore supporting the transition to a more sustainable and circular economy.
A Systematic Review and Meta-Analysis of Factors Influencing Water Use Behaviour and the Efficiency of Agricultural Production in South Africa
Authors: Kotze Heinrich C. , Qotoyi Mlibo S. M. A. , Bahta Yonas T. , Jordaan Henry , Monteiro Markus A.
Published: July 2024

Water use behaviour and efficiency are essential topics regarding water scarcity. Water is a life-sustaining resource used for various activities within the three primary sectors: agricultural, industrial, and domestic. Increasing competition among these sectors could affect the availability and sustainability of water use. The higher demand for agricultural-related commodities emphasizes the efficient and productive use of water. Still, to achieve this, the behaviour of consumers regarding water use needs to be changed. This systematic review paper aims to highlight the factors affecting water use behaviour and efficiency for agricultural production in South Africa. It further aims to determine how agricultural producers change their behaviour to improve their water use efficiency. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria were used as a reporting framework and guidelines to identify the articles included in the review. The review only included articles focussing on agricultural water use behaviour and efficiency and articles written in English and excluded articles from web pages, blogs, magazines, etc. The databases used for the review were Google Scholar and Web of Science. The articles were reviewed by the five authors to avoid the risk of bias, along with the inclusion and exclusion criteria. The final review included 30 peer-reviewed articles. A word frequency table was developed using the NVivo 14 software to conduct a thematic analysis for the review. The main factors which played a role in the water use behaviour and efficiency of farmers were (i) climate and adaptation strategies, (ii) policy and water pricing, and (iii) agricultural production and management. Each category elaborated on how water use could be improved and the different measures adopted to incorporate sustainable farm water use. This could be a guideline for farmers, stakeholders, and policymakers to improve and enhance water use behaviour and efficiency in Sub-Saharan Africa, particularly South Africa. This could ultimately assist in efficiently using the water while enhancing sustainability within the agricultural sector and attaining Sustainable Development Goal (SDG) six, which is to increase water use efficiency. The limitation of this study was that it was only narrowed down to the geographical context of South Africa. This review was funded by the Water Research Commission (WRC) of South Africa (Project Number: C20222023-00798). This review was not registered.
Multichannel Sensorimotor Integration with a Dexterous Artificial Hand
Authors: Abd Moaed A. , Engeberg Erik D.
Published: July 2024

People use their hands for intricate tasks like playing musical instruments, employing myriad touch sensations to inform motor control. In contrast, current prosthetic hands lack comprehensive haptic feedback and exhibit rudimentary multitasking functionality. Limited research has explored the potential of upper limb amputees to feel, perceive, and respond to multiple channels of simultaneously activated haptic feedback to concurrently control the individual fingers of dexterous prosthetic hands. This study introduces a novel control architecture for three amputees and nine additional subjects to concurrently control individual fingers of an artificial hand using two channels of context-specific haptic feedback. Artificial neural networks (ANNs) recognize subjects’ electromyogram (EMG) patterns governing the artificial hand controller. ANNs also classify the directions objects slip across tactile sensors on the robotic fingertips, which are encoded via the vibration frequency of wearable vibrotactile actuators. Subjects implement control strategies with each finger simultaneously to prevent or permit slip as desired, achieving a 94.49% ± 8.79% overall success rate. Although no statistically significant difference exists between amputees’ and non-amputees’ success rates, amputees require more time to respond to simultaneous haptic feedback signals, suggesting a higher cognitive load. Nevertheless, amputees can accurately interpret multiple channels of nuanced haptic feedback to concurrently control individual robotic fingers, addressing the challenge of multitasking with dexterous prosthetic hands.
Guaranteed Trajectory Tracking under Learned Dynamics with Contraction Metrics and Disturbance Estimation
Authors: Zhao Pan , Guo Ziyao , Cheng Yikun , Gahlawat Aditya , Kang Hyungsoo , Hovakimyan Naira
Published: July 2024

This paper presents a contraction-based learning control architecture that allows for using model learning tools to learn matched model uncertainties while guaranteeing trajectory tracking performance during the learning transients. The architecture relies on a disturbance estimator to estimate the pointwise value of the uncertainty, i.e., the discrepancy between a nominal model and the true dynamics, with pre-computable estimation error bounds, and a robust Riemannian energy condition for computing the control signal. Under certain conditions, the controller guarantees exponential trajectory convergence during the learning transients, while learning can improve robustness and facilitate better trajectory planning. Simulation results validate the efficacy of the proposed control architecture.
Polish Mother and (Not) Her Children: Intersectional State-Violence against Minors in Poland
Authors: Sygnowska Aleksandra
Published: July 2024

This article seeks to explain the political responsibility that Polish right-wing female politicians directly associated with the 2015–2023 Polish government and the then-ruling Law and Justice Party bear in the state-sanctioned violence against minors in the context of LGBT- and immigration-related issues. Its main assumption is that, in times of the nationalist surge that has been sweeping Poland, women using anti-LGBT and anti-immigration discourses helped to legitimize discriminatory state practices and, consequently, made a significant contribution to the enactment of white, Christian, and heteronormative identity on Polish children. Drawing upon Critical Discourse Analysis, this work examines the anti-LGBT and anti-immigration political talk by female politicians who, in their narrative strategies, adopt the position of a “Polish mother” on a mission to save a “child in danger”. Through my analysis, I aim to demonstrate that anti-LGBT and anti-immigration discourses are equally significant areas of women’s political engagement. Despite the prevalent cultural norms of caring motherhood, women do exercise their agency in political struggles as supporters of discriminatory state policies directed against minors by re-politicizing a symbolic figure of the “Polish mother”.
The Role of the Quality Management Process within Society 5.0
Authors: Maljugić Biljana , Ćoćkalo Dragan , Bakator Mihalj , Stanisavljev Sanja
Published: July 2024

This paper conducts a comprehensive review following the PRISMA methodology to explore the evolution and necessity of quality management in the era of Society 5.0, covering publications from 2017 to 2022. Through a meticulous process involving planning, conducting and reporting the review, along with a theory-driven selection and analysis of content, it aims to construct a theoretical model for quality management in Society 5.0. This model underscores the integration of quality management with Society 5.0’s principles, focusing on human-centric technological advancement and addressing social challenges to enhance life quality. The findings reveal a framework that could drive the transition to Society 5.0 by leveraging key inputs for tangible outcomes. The paper’s originality lies in its in-depth analysis and the proposed model’s potential to guide industries and governments towards sustainable development in the context of Society 5.0, marking a valuable contribution to future research in this field.
A Matter of Style: Community Building between Seduction and Indirect Communication
Authors: Vagni Tito
Published: July 2024

Diverging from studies that categorize influencers solely as advertising figures subject to interpretation within marketing frameworks, this research employs an extensive netnography to examine influencers through the lens of cultural production theory. It views them as creators and creative individuals who adeptly cultivate communities around themselves using communicative techniques akin to literary narration. On digital platforms, social connections are reshaped into a seductive game, unfolding on both aesthetic and communicative planes. This process yields influence indirectly, gradually reshaping the community imaginary, over time. Users become immersed in a realm of objects, each bearing the distinctive mark of the influencer who has imbued them with their unique style, “like that of the potter cradling a clay cup”. Influencers’ ability to invent and inhabit digital platforms effectively positions them as key figures in shaping the dynamics of these new environments.
Estimator Comparison for the Prediction of Election Results
Authors: Chalikias Miltiadis S. , Papageorgiou Georgios X. , Zarogiannis Dimitrios P.
Published: July 2024

Cluster randomized experiments and estimator comparisons are well-documented topics. In this paper, using the datasets of the popular vote in the presidential elections of the United States of America (2012, 2016, 2020), we evaluate the properties (SE, MSE) of three cluster sampling estimators: Ratio estimator, Horvitz–Thompson estimator and the linear regression estimator. While both the Ratio and Horvitz–Thompson estimators are widely used in cluster analysis, we propose a linear regression estimator defined for unequal cluster sizes, which, in many scenarios, performs better than the other two. The main objective of this paper is twofold. Firstly, to indicate which estimator is most suited for predicting the outcome of the popular vote in the United States of America. We do so by applying the single-stage cluster sampling technique to our data. In the first partition, we use the 50 states plus the District of Columbia as primary sampling units, whereas in the second one, we use 3112 counties instead. Secondly, based on the results of the aforementioned procedure, we estimate the number of clusters in a sample for a set standard error while also considering the diminishing returns from increasing the number of clusters in the sample. The linear regression estimator is best in the majority of the examined cases. This type of comparison can also be used for the estimation of any other country’s elections if prior voting results are available.