Prognostication of the development of different ovarian neoplasm for women of reproductive age
Authors: Marchenko Andrii 
Published: January 2024

The objective: to promote the efficiency of prognostication of ovarian neoplasm for women of reproductive age on the basis of the establishment of basic factors of risk.

Materials and methods. It was conducted A retrospective analysis of 500 operating rooms of protocol and histological conclusions for the purpose accordance of with clinical and pato morphologic diagnosis of the volume of operative treatment. All women were up diffused on the proper subgroups– cysts of ovaries – 284 women and benign tumours of ovaries – 216 patients. The general clinical methods of research included information on reproductive anamnesis,presence of gynaecological and extragenital diseases, therapy which is conducted, general objective inspection, special gynaecological inspection and laboratory methods of research. For the exposure of predictive factors of risk retrospectively there was the conducted analysis of anamnestic, clinical and echographic information, results of tomography, and laboratory morphological research. For statistical treatment of the results of research the generally accepted self-reactance and nonparametric methods drew on.

Results. The most meaningful factors of risk are: benign diseases of the uterus and cervix, infertility, violations of the menstrual cycle, inflammatory diseases of uterine appendages; operative interferences are carried before on the organs of the small pelvis; among extragenital pathology is high-frequency of quinsies and viral infections, disease of liver and overhead respiratory tracts, pathology of the thyroid. Summarizing the results of the preoperative echographic research of organs of the small pelvis, it would be desirable to mark the high diagnostic value of the method in differential diagnostics of cysts (94,7%) and of benign tumours of ovaries (88,4%). During the lead-through of colour Doppler mapping, there were the got signs of the benign process: absence of internally swollen bloodstream (99,3%), the middle level of resistance of vessels at the peripheral bloodstream of different intensity (45,6%). Magnetically resonance tomography after ultrasonic research was conducted 28 by a patient on the followings testimonies: the sizes of ovarian neoplasm less than 2 see and impossibility to find out new formation at ultrasonic research (r=0,32; р<0,001), heterogeneity of underlying structures of neoplasm from data of ultrasonic research (r=0,16; p=0,001) which found confirmation at operative treatment(r=-0,13; p<0,001).

Conclusion. For patients with cysts and of benign tumours of ovaries the row of general nootropic meaningful signs takes place violations of reproductive function and somatic health, most meaningful from which is: violation of menstrual cycle (cysts of ovaries – 57,5%, benign tumours – 44,9%); high-frequency of inflammatory diseases of organs of small pelvis (cysts of ovaries – 42,2%, benign tumours – 35,9%), more frequent after artificial abortions (cysts of ovaries– 50,5%, benign tumours – 40,7%); infertility of different genesis (cysts of ovaries – 36,5%, of benign tumours – 22,2%); operative interferences are carried before on the organs of small pelvis and abdominal region (cysts of ovaries – 36,5%, benign tumours – 37,6%) and disease of the liver and (cysts of ovaries – 38,6%, benign tumours – 48,1%). The group of high-risk morbidity patients belong to cysts and benign tumours of ovaries with high-frequency benign diseases of the cervix (OR=7,32) and body of the uterus (OR=6,23), infertility (OR=2,77), inflammatory diseases of organs of small pelvis (OR=2,39), with violations of the menstrual cycle (OR=2,3); with high-frequency of quinsies and viral infections (OR=6,55), diseases of the thyroid (OR=6,4), liver (OR=4,59) and overhead respiratory tracts (OR=4,32) which do not use rational contraception (OR=2,09). The got results must be taken into account in prognostication of ovarian neoplasm for women of reproductive age.