bluuebunny/crossref_metadata_2025 huggingface dataset:
Alumbrado Público Fotovoltaico: Análisis de Viabilidad Técnica, Económica, y Social
Authors: Orejón Sánchez Rami D. , Gago Calderón Alfonso
Published: March 2022

Este trabajo analiza la viabilidad de proyectos consistentes en instalaciones de alumbrado público (AP) alimentadas con energía solar fotovoltaica en base a diferentes criterios. En primer lugar se plantea un análisis de la capacidad tecnológica existente en este mercado para alumbrado exterior. En segundo lugar se comparan los requisitos, trabajos necesarios, problemática y costes identificables entre las opciones de planificar y ejecutar el soterramiento del tendido eléctrico y la instalación de nuevas luminarias fotovoltaicas (PV) LED autónomas para cubrir los requisitos normativos exigidos de alumbrado público de calles y vías. Este punto se plantea en base al marco de un caso práctico localizado en un municipio de la Isla de Lanzarote, Las Palmas, con una población en torno a 5.000 habitantes.

El trabajo se completa presentando un estudio estadístico que valora la aceptación social de ciudadanos españoles asociada a este tipo de tecnología en entornos urbanos, desde los aspectos de la mejora de la sostenibilidad urbana, la seguridad de funcionamiento, el impacto visual y la percepción del riesgo de vandalismo
Moreno Trapiella, P.C. Ejecución hipotecaria. Jurisprudencia del TJUE sobre las cláusulas abusivas
Authors: Arribas y Atienza Patricio
Published: March 2022

La Unión Europea siempre ha tenido como objetivo la armonización del Derecho de losdiferentes países miembros, e incluso se ha llegado a plantear la posibilidad deelaborar un código europeo común de derecho privado y si bien estamos lejos dealcanzar esos objetivos, e incluso aparecen movimientos en algunas regiones quepretenden desmembrar aún más el Derecho civil nacional. Pero afortunadamente laexistencia de una estructura judicial propia en la Unión Europea y el reconocimiento dela prevalencia del Derecho europeo sobre el nacional que conlleva a la necesariacompatibilidad de sus normas con las emanadas de la Unión, constituye un avanceque esperemos no tenga vuelta atrás.Para ello se introdujo en el artículo 267 del Tratado de Funcionamiento de la UniónEuropea (TFUE) (1), la denominada cuestión prejudicial europea, conforme a la cual,si en el momento de aplicar una norma nacional hubiese dudas sobre su adaptación aotra norma de la Unión, podrá el Juez nacional plantear al Tribunal de Justicia de laUnión Europea la cuestión.Por otro lado, con la finalidad de proteger a los consumidores se dictó la Directiva93/13/CEE del Consejo de 5 de abril de 1.993, relativa a cláusulas abusivas encontratos celebrados con consumidores.Con estos mimbres y a principio de esta década es, que comienzan a plantearse pordiversos jueces y tribunales diferentes cuestiones prejudiciales europeas planteando lacompatibilidad de la normativa nacional, especialmente en el ámbito del contrato dehipoteca por parte de los consumidores con la mencionada directiva.
Application of The Problem Solving Learning Model Assisted by Roulette Media in Student History Subjects in Aceh Besar District
Authors: Nurvazillah Nurvazillah , Kamza Muhjam
Published: March 2022

This study aims to find out how the application and response of class XI IPS 1 students in the application of problem solving learning models assisted by roulette media in history learning at SMA Negeri 1 Kuta Cot Glie, Aceh Besar District. This research uses a qualitative approach with descriptive research type and the sampling purposive sampling. The subjects in this study were students of class XI IPS 1, totaling 24 students. Based on the results of the research, it is known that (1) The application of the problem solving learning model assisted by roulette media in history learning in class XI IPS 1 has been carried out well according to the problem solving syntax. This can be seen from the results of the analysis of the application of the learning model, an average score of 78,3% is included in the good criteria and the results of the learning mastery analysis show that 21 people scored above the minimum criteria of mastery learning or equivalent to 87,5%, while 3 people scored below the minimum criteria of mastery learning or equivalent to 12,5%. (2) The response of class XI IPS 1 students in the application of learning with problem solving models assisted by roulette media is good. This can be seen from the activities and behavior of students shown in learning activities, students listen and follow the teacher’s directions in accordance with the learning syntax. Students solve  the problems given by the teacher carefully and keep the class organized.
Development of Nutmeg Sweets Making Business in Gampong Hilir, Tapaktuan District 1978 – 2021
Authors: Dayanti Oppy Chotsria
Published: March 2022

The study, entitled "Business Development of Candied Nutmeg Making UD. Dianti Gampong Hilir Kecamatan Tapaktuan 1978 - 2021 "This aims to determine the initial process of the birth of the business of making candied nutmeg of UD. Dianti Gampong Hilir, Tapaktuan District from 1978-2021 and to find out how the development of the business of making candied nutmeg UD. Dianti Gampong Hilir, Tapaktuan District from 1978 - 2021. This study uses a qualitative approach to the type of historical research. The subjects in this study were the owners of candied nutmeg. Data collection techniques using observation and interview techniques. All data from observations and interviews were processed with the data analysis stage, namely, data reduction, data presentation, and verification / drawing conclusions. The results of this study can be concluded that the development of the business of making candied nutmeg UD. Dianti Gampong Hilir, Tapaktuan District is quite good. Among them, the owner of candied nutmeg is getting more advanced than usually selling only candied nutmegs but now there are new products produced by the owner of candied nutmeg due to business development from year to year.
The Role of the Ummul Ayman Islamic Boarding School in Samalanga District, Bireuen Regency in the Education of Children Victims of the Aceh Conflict, 1990-2021
Authors: Yuriza Sinthia , Haikal Muhammad
Published: March 2022

This study aims to find out how (1) the background of the birth of the Ummul Ayman Islamic Boarding School was, (2) the education management system of the Ummul Ayman Islamic Boarding School was in handling children victims of the Aceh conflict before the Helsinki MoU. (3) the education management system of the Ummul Ayman Islamic Boarding School in handling children victims of the Aceh conflict after the Helsinki MoU, (4) the results of the education process for children of Aceh conflict victims at the Ummul Ayman Islamic Boarding School were . The approach used in this research is a qualitative approach with data collection techniques in the form of interviews, documentation, and literature studies. The results of this study are (1) the background of the establishment of the Ummul Ayman Islamic Boarding School when conditions in Aceh were being hit by armed conflict which caused many negative impacts and the destruction of the social order of society in various aspects of life , especially in the aspect of education. (2), the education management system of the Ummul Ayman Islamic boarding school before the peace in Aceh followed the national education system, while the non-formal education system of the Ummul Ayman Islamic boarding school followed the Dayah Salafiyah method. (3) After the MoU in Helsinki, the situation in the Aceh Province began to improve, Islamic boarding schools began to be built. (4), the results of the education process for children victims of the Aceh conflict at the Ummul Ayman Islamic Boarding School after they leave or finish there are ustadz/teaching staff, establish study centers, writers, and continue
Impact of School Plant on English Teachers Job Performance in Public Secondary School Federal Capital Territory, Abuja, Nigeria
Authors: Fatimayin Foluke , Jacob Ogunode Niyi
Published: March 2022

This study investigated impact of schools plant on English Teachers job performance and students’ academic performance in public secondary schools in FCT, Abuja, Nigeria. The study adopted a descriptive research design with a population of all the English language Teachers and English students in the public secondary schools in FCT. Simple random sampling technique was used to select 120 English Teachers and 300 English students (SS2). Questionnaire was adopted as data collection instrument. The instrument used to collect data was the ‘Impact of School Plant on Teachers Job Performance and Student Academic Performance Questionnaire (ISPTJPQ)’. The questionnaire has sections A and B. Section A was on personal data of the respondents while section B provided answers to the research questions raised for the items on a modified Likert scale of measurement: Strongly agree (SA), agree (SA), disagree (D), Strongly disagree (SD). The reliability of the instrument was established through the test-retest method. The two sets of responses were correlated using Pearson’s Product Moment Correlation and a reliability coefficient of 0.84 was obtained. Data collected were analysed using the mean, percentage, Pearson’s Product Moment Correlation (r), Zero Differentiation Hypothesis statistical. The findings showed that there is significant relationship between school plant and English language teachers’ job performance in public secondary schools. The result also indicated that there is significant relationship between school plant and academic performance of students in public secondary schools.
HUBUNGAN BIMBINGAN KARIR DAN KEPERCAYAAN DIRI DENGAN PERENCANAAN KARIR PESERTA DIDIK KELAS XII MIPA SMA NEGERI 2 TEGAL
Authors: Essa Putra Lukita  , Budisiwi Hastin , Hanung Sudibyo
Published: March 2022

Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara bimbingan karir dan kepercayaan diri dengan perencanaan karir pada peserta didik kelas XII MIPA SMA Negeri 2 Tegal Tahun Pelajaran 2020/2021. Penelitian ini menggunakan pendekatan kuanitatif. Teknik sampling yang digunakan dalam penelitian ini adalah teknik probably sampling dengan jenis simple random sampling. Adapun cara pengambilan data yaitu dengan menggunakan teknik observasi,kuesioner dan dokumentasi. Berdasarkan data yang diperoleh terdapat hubungan antara bimbingan karir dengan perencanaan karir. Hal ini ditunjukan dari nilai Koefisien regresi variabel bimbingan karir yaitu bernilai positif sebesar 0,82; artinya jika bimbingan karir mengalami kenaikan 1%, maka perencanaan karir akan mengalami peningkatan sebesar 0,82. Semakin tinggi bimbingan karir maka semakin tinggi perencanaan karir peserta didik. Sama halnya dengan kepercayaan diri, terdapat hubungan kepercayaan diri dengan perencanaan karir. Hal ini ditunjukan dari nilai Koefisien regresi variabel kepercayaan diri yaitu bernilai positif sebesar 0,041; artinya jika kepercayaan diri mengalami kenaikan 1%, maka perencanaan karir akan mengalami peningkatan sebesar 0,041. Semakin tinggi bimbingan karir maka semakin tinggi perencanaan karirpeserta didik.

Berdasarkan hasil penelitian, terdapat hubungan positif antara variabel bimbingan karir, kepercayaan diri dan perencanaan karir. Hal ini ditunjukan dari perhitungan uji regresi bersama-sama (Uji F), nilai Fhitung adalah 5,04. Jadi nilai Fhitung > Ftabel atau 5,04 > 3,47, artinya H03 ditolak dan Ha3 diterima. Berdasarkan uji F yang telah dilakukan, maka dapat disimpulkan bahwa terdapat hubungan yang positif dan signifikan antara bimbingan karir dan kepercayaan diri dengan perencanaan karir pada peserta didik kelas XII MIPA SMA Negeri 2 Tegal Tahun Pelajaran 2020/2021.
Relationship between stress and bruxism among university students: a cross-sectional study
Authors: De Oliveira Dhelfeson Douglas , Brum-Júnior Jadimar , Soares Luana , Cerqueira Wyllerson , Costa Igor , Oliveira Evandro , Gomes Gabriela , Murta Agnes , Tavano Karine Taís , Galvão Endi , Gonçalves Patricia , Dumont Flecha Olga
Published: March 2022

Background: Bruxism is defined as repetitive masticatory muscle activity characterized by clenching or grinding of the teeth and it has been related to psychological factors, such as personality traits, anxiety and stress.
Objective: To investigate association between stress and bruxism among university students.
Materials and methods: Lipp's Stress Symptoms Inventory for Adults (LSSI) was applied to 253 university students in Diamantina, Brazil. They were clinically evaluated to verify dental wear. The non-instrumental evaluation of probable bruxism was determined by the patients’ reports. Sociodemographic variables and self-reported stress data were collected by using the questionnaire. The chi-square test was used, and significance level of 5% (p<0.05) was adopted.
Results: The prevalence of bruxism was 45.8% and stress, 37.9%. There was no significant association between the presence of stress diagnosed by ISSL and bruxism (p = 0.815). Among the students diagnosed as stressed, 31.6% were in the resistance phase. Self-reported stress was associated with the habit of tooth grinding (p < 0.001).
Conclusions: No association was found between stress and bruxism. Nevertheless, the prevalence of bruxism among these students was considered high.
Types of retention for implant-supported fixed prosthesis: a narrative literature review
Authors: Almeida-Mares Clara , Metzker Lyra Fernando Teodoro , Rocha Dias Danilo , Santos Lages Fedrerico
Published: March 2022

Background: The development of implant dentistry, along with implant-supported prostheses, made it possible to carry out functional and aesthetic rehabilitation treatments for patients, promoting comfort and durability in the results. For the achievement of the rehabilitation treatment, the choice of the retentive system of the prosthesis that best suits the patient's expectations, together with their clinical and radiographic conditions is essential.
Objective: Perform a literature review addressing the main retention systems for fixed prostheses on implants, especially screwed and cemented, contextualizing them with new materials, components and techniques, guiding the decision-making of dental surgeons for their clinical planning.
Materials and methods: A bibliographic search was performed on MEDLINE, Embase, Cochrane Library and SciElo platforms, filtering articles in Portuguese or English, with no date restriction until June 2, 2021.
Conclusion: The choice of the retention system to be used involves several factors. A gold standard retention technique has not yet been established, due to the advantages and disadvantages of each. The choice of retention method must be made in conjunction with the patient and more clinical studies with longer follow-up are necessary to obtain more information.
3D Printing in Dental Science
Authors: Cruz Olivo Edison Andrés
Published: March 2022

3D printing is a technology that describes a manufacturing process previously planned and designed in a computer to create an object 1,2. This technology was introduced in dentistry by Chuck Hull since 1986 and allowed the automation and thus improved dental workflow 2. Technologies used in 3D printing involves: Stereolithography (SLA), bioprinting, fused deposition modeling (FDM), selective laser sintering (SLS), and PolyJet printing. We can choose one of them depending on the clinical use and material, need of accuracy among others.  
To 3D printing you need to use a scanner with an integrated software in order to capture the 3D images of the object being scanned. Those 3D images are stored in Standard Tessellation Language (STL) file 3. But what “Tessellation” means? Tessellation is the covering process of a surface, using one or more geometric shapes, with no overlaps and no gaps. It means that the object scanned is copied in detail with high reliability and then can be printed.  
Before printing, the software cuts the STL file into multiple horizontal layers and creates the G-code for the machine command for the printer. Thus, the resolution of the printer is determined by its layer thickness (z-axis) which represents the vertical accuracy of 3D printer 1. There are two approaches used to fabricate 3D objects: subtractive approach (milling); additive approach (layered manufacturing) 4 . The first, normally use a small model or block to machining it and is indicated to fabricate ceramic crowns in dentistry. The last, can produce complex structures and thus is suitable for reproduce the anatomy of different structures of oral cavity 4.
3.63 Ga grey gneisses reveal the Eoarchaean history of the Zimbabwe craton
Authors: Hofmann A. , Kröner A. , Iaccheri L.M. , Wong J. , Geng H. , Xie H.
Published: March 2022

Grey gneisses from the Tokwe and Rhodesdale terrains of the Zimbabwe craton have zircon ages of ~3.63, 3.52, and 3.34 Ga, validating the existence of Eo- to Palaeoarchaean crust. In-situ zircon Hf isotope compositions reveal the interplay between episodes of juvenile magma addition, crustal thickening and crustal differentiation. Starting from juvenile mafic crust (with chondritic composition) at ~3.9 Ga, the oldest nucleus of the Zimbabwe craton developed into a stable crustal block by ~3.35 Ga, following a tectonic and mantle evolution that is mirrored by other ancient terrains.
Weekly Isotretinoin Therapy (WIT) Study: A Potential Alternative for the Treatment of Moderate Acne Vulgaris
Authors: Karlin Samantha , Ritter Alexandra , Linkous Courtney , Wehlage Katherine , Wine Lee Lara
Published: March 2022

Background: Treatment options for moderate acne remain limited.

Methods: We evaluated the efficacy of once-weekly dosed isotretinoin for moderate acne. Nineteen participants took isotretinoin dosed at 1-1.5 mg/kg/week for four months. Patient clinical improvement, quality of life, and adverse effects were measured at baseline and at monthly follow-up visits. Laboratory monitoring was performed at baseline and after two months.

Results: Ninety-five percent of patients (18/19) had improvement in their acne. The majority (68%) went from a baseline of moderate acne (score 3) to either clear (score 0) or almost clear (score 1) by the end of four months. There were no major lab abnormalities or adverse events. Eighty-nine percent of patients (17/19) reported improvement in their quality of life.

Conclusion: Once weekly isotretinoin may be an additional treatment option for patients with moderate acne.
Döviz kuru enflasyon ve dış ticaret arasındaki ilişkinin ekonometrik bir analizi: Türkiye örneği
Authors: AYTEKİN İbrahim , UÇAN Okyay
Published: March 2022

Sanayi Devrimi ve küreselleşme Dünya’yı hızla tek bir pazar haline dönüştürmüştür. Bu durum dış ticareti ülkeler için önemli bir iktisadi faaliyet kolu haline getirmiştir. Böylece ülkeler için büyük bir önem kazanan dış ticaret, dövize olan küresel talebi de arttırmıştır. Dış ticaret ile etkileşim halinde olan döviz kuru aynı zamanda ülkelerin enflasyon rakamlarını da etkilemektedir. Bu doğrultuda bu çalışmanın amacı, Türkiye’nin 2004:M1–2019:M12 yılları arasındaki aylık; döviz kuru, enflasyon, ihracat ve ithalat serileri arasında bir ilişkinin olup olmadığını ekonometrik bir yöntemle incelemektir. Çalışmada ilk olarak teorik çerçeve ve literatür incelemesi ele alınmış ardından ekonometrik analize geçilmiştir. Ekonometrik analizde ilk olarak serilere genişletilmiş Dickey-Fuller birim kök testi uygulanmış ve serilerin birinci farkta durağan oldukları anlaşılmıştır. Ardından serilere Johansen eşbütünleşme testi uygulanmış ve serilerin eşbütünleşik oldukları tespit edilmiştir. Analizin son aşasında ise Granger nedensellik testi yapılmış ve bu testin sonucunda, Türkiye’nin 2004-2019 yılları arasında yapmış olduğu ihracat ile ithal arasında çift yönlü bir nedensellik ilişkisinin varlığına rastlanmıştır. Ayrıca döviz kurundan enflasyon ve ihracata doğru tek yönlü bir nedensellik ilişkisinin olduğu gözlemlenmiştir. Nihayetinde çalışmada Türkiye’nin; döviz kuru, enflasyon, ihracat ve ithalat rakamlarının uzun dönemde birbirlerini etkiledikleri sonucuna ulaşılmıştır.
Entegre raporlama ve güvence
Authors: ZOZİK Adalet , DOĞAN Zeki
Published: March 2022

Paydaşların farklı ihtiyaçlarını karşılamak üzere çeşitli raporlama modelleri mevcuttur. Bununla birlikte, yıllardır süregelen arayışlar sonucu mevcut raporların eksikliklerini tamamlamayı amaçlayan entegre raporlama kavramı ortaya çıkmıştır. Entegre raporlama uygulamaları, hem iş dünyası hem de diğer paydaşlar arasında oldukça dikkat çekmektedir. Bu çalışmada, entegre raporlama ve bağımsız dış güvence konusu incelenmiştir. Bu bağlamda entegre düşünce yaklaşımı, kuruluşların entegre raporlamayı benimsemesinin nedenleri, Uluslararası Entegre Raporlama Çerçevesi ve entegre raporlamanın işletme içi/dışı bilgi kullanıcıları için faydaları ve finansal/finansal olmayan bilgi bileşenleri için güvence konusu ayrıntılarıyla ele alınmıştır. Sonuç olarak, yeni bir kurumsal yaklaşımı olan entegre raporlama ile birlikte güvence/bağımsız denetim konusu da dikkat çekmektedir. Bu kapsamda, finansal ve finansal olmayan bilgi bileşenlerinin denetim sürecinde bir araya nasıl getirileceği, entegre raporun alt bileşenlerinden olan finansal olmayan bilgi için güvencenin nasıl sağlanacağı, finansal olmayan bilgilere ilişkin standartların oluşturulmasından hangi kurum yada kuruluşların sorumlu olacağı, finansal olmayan bilgilere ilişkin denetim standartlarının yeterli olup olmadığı, bağımsız dış güvenceyi hangi kurum yada kuruluşların sağlayacağı, bağımsız dış güvenceyi sağlayan kurum yada kuruluşların sorumluluğunun ne olacağı, bağımsız dış güvencenin etkin bir maliyetle yapıpılıp/yapılamayacağı gibi sorulara cevap aranmaktadır.
TMS-37 çerçevesinde karşılıkların, koşullu borçların, koşullu varlıkların karşılaştırılmalı olarak incelenmesi ve muhasebe uygulamaları
Authors: ÖZULUCAN Abitter
Published: March 2022

Bu çalışmada, TMS 37 kapsamında karşılıklar, koşullu borçlar ve koşullu varlıkların önce kavramsal olarak sonra da uygulamada sıklıkla karşılaşılan olaylardan örnekler verilerek özelliklerinin tanıtılmasına, ölçüm esaslarına, hangi durumlarda muhasebeleştirileceklerine, hangi durumlarda mali tablo dipnotlarında yer verileceklerine, belirli dönemlerde değerlemelerine ve sonuçların güncellenmelerine ve iptallerine ilişkin açıklamalarda bulunulmuştur. Özü itibariyle “karşılık” kavramı, mali tablolara yansıtılma koşullarını sağlayan yükümlülük olarak kabul edilirken, mali tablolara yansıtılması mümkün olmayan sadece dipnotlarda yer verilen muhtemel yükümlülükler “koşullu borç” olarak işlem görmelidir. Koşullu varlık kavramı sözü edilen her iki kavramdan farklıdır. Çünkü “koşullu varlıklar”, işletmelerin ileri tarihte elde etmeyi düşündükleri muhtemel varlıkları niteliğindedir. Sonuçta belirsizlikler nedeniyle ortaya konulan bilgilerin kişilerin değer yargısına dayandığı ve bu yargılar esas alınarak mali tablolarda ve dipnotlarda bilgi ortaya konulduğu göz ardı edilmeden, bu bilgileri kullanma durumunda olan tüm paydaşların daha sağlıklı karar almaları mümkün olabilecektir.
Synthese und Röntgenstruktur einer Triafulvalen-Vorstufe
Authors: Engel Peter , Läng Christoph , Mühlebach Michel , Neuenschwander Markus
Published: March 2022

Triafulvalene precursors 3b and 3c have been synthesized by CuII-catalyzed 'carbene dimerization' of cyclopropyl carbenoids (obtained by halogen-lithium exchange of 1,1-dibromo-2-(phenylthio)-3-(trimethylsilyl)cyclopropane (2b; see Scheme 2) in moderate yields. Diastereoselectivity of the central step 2b → 3b is low. An X-ray analysis of the predominantly formed trans-anti isomer has been performed.
Triafulven- und Calicen-Vorstufen für retro-Diels-Alder Reaktionen
Authors: Mühlebach Michel , Neuenschwander Markus
Published: March 2022

An attractive concept for the synthesis of triafulvene (1) and calicene (2) by retro-Diels-Alder reaction (RDA reaction) of precursors 3 and 4 is presented. Precursors 3 and 4 are easily available in three steps starting with dibenzobarrelene (5). First thermal-fragmentation experiments are summarized.
Synthesis of Cyclic α-Diones, a Class of Natural Flavor Compounds
Authors: Wild Hannes , Huber Ulrich , Fráter Georg
Published: March 2022

A practical and generally applicable synthesis of the important flavor ingredients corylone (5) and its alkyl homologues 11, 13, 15, and 16 is described, based on alkylation of methyl 4-methoxyacetoacetate (6) with an α-chloro-ketone and subsequent cyclization, hydrolysis, and decarboxylation. The one-pot transformation of methyl 4-chloroacetoacetate to 17 through four consecutive steps is demonstrated. The principle has also been used to prepare the six-membered ring analogues 23 and 24.
Application de méthodes d'analyse statistique univariée et multivariée à l'étude parallèle de critères chimiques, biochimiques, rhéologiques, microbiologiques et sensoriels du fromage d'emmental au moment de sa taxation Partie I: Analyse de quelques profils de distribution
Authors: Bosset Jacques O. , Collomb Marius , Eberhard Pius , Grand Marius , Lavanchy Pierre , Kaufmann Erwin , Kreuter Ulrich
Published: March 2022

This multidisciplinary study of Swiss Emmental cheese relates values determined by chemical, biochemical, rheological, and bacteriological analyses to those obtained by sensoric analysis of taste as well as tactile and visual properties. To this effect, 50 four-months-old Emmental loaves
of different qualities were chosen at their taxation and submitted to 165 analyses; six of these analyses were sensoric evaluations. The instrumental analyses included quantitative determination of water, fat, salt, volatile fatty acids, lactic acid (L and D), nitrogen fractions (TN, WSN,
NPN), ammonia, free amino acids, biogenic amines, one peptide, and volatile components. The latter were analyzed with two different methods. Moreover, two microbiological analyses were carried out (non-lactic-acid bacteria and streptococci of group D), four rheological measurements
(penetration depth, stress at 33% deformation, compression rate and stress at peak stress point) and determination of three colour components according to Hunter. The sensoric taste analysis permitted us to evaluate the flavour development, the typical character and the quality of the
cheese. The tactile analysis enabled us to characterize the texture, structure, and consistency and the visual evaluation to examine the eyes of the cheese body. The first part of this paper divided into 3 parts deals with univariate analysis of distribution profiles of some characteristic
measurable variables for Swiss Emmental cheese.
Lebensmittelkontamination durch Mykotoxine: eine Übersicht
Authors: Cerny Milan S.
Published: March 2022

Mycotoxins can cause adverse health effects in humans and animals. Therefore, it is important to control their presence in foods and feeds. For the following mycotoxins: aflatoxins, ochratoxins, fusarium toxins (trichothecenes, zearalenone, fumonisins), patulin, and ergot alkaloids,
up-to-date information concerning the occurrence, toxicological aspects, legal regulations, and analytical methods has been reviewed. The current situation of the mycotoxin contamination and monitoring in Switzerland is discussed.
New [4 + 2] Cycloadditions of in situ Generated Indolyl Enol Ethers and Their Anions with Dimethyl Acetylenedicarboxylate: A One-Pot Access to 4-Alkoxy-Substituted Carbazoles
Authors: Pindur Ulf , Rogge Martina
Published: March 2022

The 3-indolyl(methyl)methoxycarbenium tetrafluoroborates 1a-d were deprotonated with NaH to furnish in situ the highly reactive 3-indolyl enol ethers 2a or their corresponding 3-indolyl enol ether anions 2b. Subsequent trapping of the enol ethers 2 with dimethyl acetylenedicarboxylate gave rise to 4-methoxy-functionalised carbazole derivatives in a HOMO(diene)-LUMO(dienophile)-controlled [4 + 2] cycloaddition. After variation of the 3-indolyl(alkoxy)carbenium tetrafluoroborates 1, Michael-type adducts and a ring-opened, biaryl product 6 were formed additionally.
Photoactivation Properties of Self-n-Doped Perylene Diimides: Concentration-Dependent Radical Anion and Dianion Formation
Authors: Powell Daniel , Rhodes Zayn , Zhang Xinwen , Miller Jacob , Jonely McKenzie , Hansen Kameron , Nwachukwu Chideraa , Roberts Andrew , Wang He , Noriega Rodrigo , Minteer Shelley , Whittaker-Brooks Luisa
Published: March 2022

Perylene diimides (PDIs) have garnered attention as organic photocatalysis in recent years for their ability to drive challenging synthetic transformations, such as aryl halide reduction and olefin iodoperfluoroalkylation. Previous work in this area employs spectator pendant groups attached to the imide nitrogen positions of PDIs that are only added to impart solubility. In this work, we employ electron-rich ammonium iodide or ammonium hydroxide pendant groups capable of self-n-doping the PDI core to form radical anions (R●―) and dianions (D●●―). We observe R●― formation is favored at low concentrations where aliphatic linkers are able to freely rotate, while D●●― formation is favored at elevated concentrations likely due to Coulombic stabilization between adjacent chromophores in a similar manner to that of Kasha exciton stabilization. Cyclic voltammetric measurements are consistent with steric encumbrance increasing the Lewis basicity of anions through Coulombic destabilization. However, sterics also inhibit dianion formation by disrupting aggregation. Finally, femtosecond transient absorption measurements reveal that low wavelength excitation (400 nm) preferentially favors the excitation of R●― to the strongly reducing doublet excited state 2[R●―]*. In contrast, higher wavelength excitation (520 nm) favors the formation of the singlet excited state 1[N]*. These findings highlight the importance of dopant architecture, counterion selection, excitation wavelength, and concentration on R●― and D●●― formation, which has substantial implications for future photocatalytic applications. We anticipate these findings will enable more efficient systems based on self-n-doped PDIs.
Beyond Atoms and Bonds: Contextual Explainability via Molecular Graphical Depictions
Authors: Bertolini Marco , Zhao Linlin , Clevert Djork-Arné , Montanari Floriane
Published: March 2022

The field of explainable AI applied to molecular property prediction models has often been reduced to deriving atomic contributions. This has impaired the interpretability of such models, as chemists rather think in terms of larger, chemically meaningful structures, which often do not simply reduce to the sum of their atomic constituents. We develop an explanatory framework yielding both local as well as more complex structural attributions. We derive such contextual explanations in pixel space, exploiting the property that a molecule is not merely encoded through a collection of atoms and bonds, as is the case for string- or graph-based approaches. We provide evidence that the proposed explanation method satisfies desirable properties, namely sparsity and invariance with respect to the molecule’s symmetries.
Boron-promoted Deprotonative Conjugate Addition: Development of Geminal diborons as Versatile Soft Pronucleophiles and Acyl An-ion Equivalents
Authors: Wang Lucia , Lin Shengjia , Santos Emmanuel , Pralat Jenna , Spotton Kaylyn , Sharma Abhishek
Published: March 2022

Conjugate addition of α-boron stabilized carbanions is an underexplored reaction modality. Existing methods require deborylation of geminal di/triboryl alkanes and/or the presence of additional activating groups. We report the 1,4-addition of α,α-diboryl carbanions generated via deprotonation of corresponding geminal diborons. The methodology enabled a general route to highly substituted and synthetically useful γ,γ-diboryl ketones. The development of geminal diborons as soft pronucleophiles also enabled their use as acyl anion equivalents via one-pot tandem conjugate addition-oxidation sequence.
Influence of ring modifications on nucleolar stress caused by oxaliplatin-like compounds
Authors: McDevitt Christine , Guerrero Andres , Smith Haley , DeRose Victoria
Published: March 2022

Oxaliplatin, a platinum compound in broad clinical use, can induce cell death through a nucleolar stress pathway rather than the canonical DNA damage response studied for other Pt(II) compounds. Previous work has found that the oxaliplatin 1,2-diaminocyclohexane (DACH) ring but not the oxalate leaving group is important to the ability to induce nucleolar stress. Here we study the influence of DACH ring substituents at the 4-position on the ability of DACH-Pt(II) compounds to cause nucleolar stress. We determine that DACH-Pt(II) compounds with 4-position methyl, ethyl, or propyl substituents induce nucleolar stress, but DACH-Pt(II) compounds with 4-isopropyl substituents do not induce nucleolar stress. This effect is independent of whether the substituent is in the axial or equatorial position relatively to the trans diamines of the ligand. These results suggest that spatially sensitive interactions could be involved in the ability of platinum compounds to cause nucleolar stress.
Monobodies with potent neutralizing activity against SARS-CoV-2 Delta and other variants of concern
Authors: Kondo Taishi , Matsuoka Kazuhiro , Umemoto Shun , Fujino Tomoshige , Hayashi Gosuke , Iwatani Yasumasa , Murakami Hiroshi
Published: March 2022

Neutralizing antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are useful for patients’ treatment of the coronavirus disease 2019 (COVID-19). We report here affinity maturation of monobodies against the SARS-CoV-2 spike protein and their neutralizing activity against SARS-CoV-2 B.1.1 (Pango v.3.1.14) as well as four variants of concern. We selected matured monobodies from libraries with multi-site saturation mutagenesis on the recognition loops through in vitro selection. One clone, the C4-AM2 monobody, showed extremely high affinity (KD < 0.01 nM) against the receptor-binding domain of the SARS-CoV-2 B.1.1, even in monomer form. Furthermore, the C4-AM2 monobody efficiently neutralized the SARS-CoV-2 B.1.1 (IC50 = 46 pM, 0.62 ng/ml), and the Alpha (IC50 = 77 pM, 1.0 ng/ml), Beta (IC50 = 0.54 nM, 7.2 ng/ml), Gamma (IC50 = 0.55 nM, 7.4 ng/ml), and Delta (IC50 = 0.59 nM, 8.0 ng/ml) variants. The obtained monobodies would be useful as neutralizing proteins against current and potentially hazardous future SARS-CoV-2 variants.
Restoring Relevance: Interpreting the historic ritual of pilgrimage in New Zealand to restore relevance to theological architecture
Authors:   , Murphy Katie-Rose
Published: March 2022

In New Zealand’s increasingly secular society, theological architecture
has become more and more obsolete. Although certainly still practiced,
religion is no longer an integral part of everyday life in New Zealand
culture. The church is now but a shadow of its former power and
influence. This thesis seeks to reconnect theological architecture in
today’s modern New Zealand society by rethinking and challenging the way
Catholics can practice, through the design medium of architecture. This
research looks at how an element of the old can be taken and
reinterpreted to generate the new. This has been tested using the
ancient practice of Pilgrimage in the context of New Zealand landscape.
The typically arduous and prolonged nature of this sacred journey could
offer a different religious experience that doesn’t currently exist in
New Zealand. The increased time duration of the journey leads to
increased contemplation and anticipation to ultimately lead to a deeper
spirituality. The concept of pilgrimage integrates with our New Zealand
culture. It parallels in a secular sense with our characteristic New
Zealand outdoor hiking and adventurous culture. Taking New Zealand’s
beautiful clean green landscape image and framing it in a Catholic
setting as the holy land that God created can be a way of applying
religious principles to a new setting, one that is more relevant to
current society. This concept also draws on human’s natural spiritual
connection with nature, highlighting the power of the earths sanctity.
This concept has been tested at two different architectural scales,
firstly considering the overall route of the pilgrimage and secondly
focusing on the culmination site where pilgrimage is also evident within
the church building itself.
The early history of Te Aute College, 1854-1912 : together with a sketch, 1912-1949
Authors:   , Alexander Robert Ritchie
Published: March 2022

The History of Te Aute College appears to be an unexplored, great, wide
field, for developments in this, college effected the whole Maori
race. Hence it was with trepidation that this piece of research was started.
Material was not scarce, so that to write a history which might not be
too sketchy, could be done, but not within a hundred pages. So then the
decision was made to write the "Early History of Te Aute College",
adding an outline sketch of developments and policies leading up to the
present day.
Simulasi Berbasis MEH untuk Pemodelan Distribusi Potensial Listrik dan Medan Listrik pada Isolator Porselen 20 kV
Authors: NURHAKIM ASHADI AMIR , AR RASYID ROBBY IKHSAN , WALUYO WALUYO
Published: March 2022

AbstrakIsolator adalah suatu perlengkapan yang cukup berarti dalam saluran udara tegangan menengah. Distribusi potensial serta medan listrik di sekitar isolator ialah wilayah yang masih mendapat pengaruh sifat kelistrikan dari suatu muatan. Riset ini mengulas simulasi distribusi potensial serta medan listrik pada isolator tegangan menengah berjenis porselen berbasis metode elemen hingga (MEH). Metode ini digunakan agar memudahkan dalam mengukur pendistribusian potensial listrik dan medan listrik pada isolator karena merupakan salah satu metode numerik yang lebih praktis untuk memecahkan masalah elektrostatik. Dari hasil simulasi 3D diperoleh pola distribusi potensial listrik selalu mengikuti kontur dari isolator sedangkan untuk distribusi medan listriknya mencapai nilai tertinggi sebesar 5,3 kV/cm. Sedangkan dari grafik distribusi medan listrik terlihat lebih jelas bahwa stress medan listrik yang besar terdapat pada daerah koneksi antara isolator dengan konduktor serta  isolator dengan ground.Kata kunci: Isolator Porselen, Medan Listrik, Metoda Elemen Hingga (MEH), Potensial Listrik.AbstractAn insulator is a fairly significant piece of equipment in a medium-voltage overhead line. The distribution of potential and electric field around an insulator is an area that is still affected by the electrical properties of a charge. This research reviews the distribution of potential and electric field simulations on porcelain-type medium-voltage insulators based on the finite element method (FEM). This method is used to make it easier to measure the distribution of electric potential and electric field on an insulator because it is one of the more practical numerical methods for solving electrostatic problems. From the 3D simulation results, the distribution pattern of the electric potential always follows the contours of the insulator, while the electric field distribution reaches the highest value of 5.3 kV/cm. Meanwhile, from the electric field distribution charts, it is clearer that the large electric field stress is found in the area around the insulator with conductors and insulators with ground.Keywords: Porcelain Insulator, Electric Field, Finite Element Method (FEM), Electric Potential.
Pemodelan Analisis Sentimen Masyarakat terhadap Adaptasi Kebiasaan Baru (AKB) mengunakan Algoritma Naïve Bayes
Authors: YULIYANTI SITI , SHOLIHAH SITI
Published: March 2022

AbstrakPandemi Covid-19 hampir masuk tahun ke dua di Indonesia, pemerintah terus berupaya menekan laju peningkatan penularan Covid-19 melalui berbagai media. Sosialisasi dan informasi melalui media sosial yang merupakan wadah paling cepat untuk tersampaikan kepada masyarakat. Berbagai istilah digunakan seperti adaptasi kebiasaan baru, social distancing, PSBB sampai PPKM sehingga memicu masyarakat untuk beropini di media sosial. Penelitian ini menganalisis sentiment masyarakat terkait opini peningkatan Covid-19 dari twitter. Klasifikasi tweet menggunakan Naive Bayes dengan penambahan seleksi fitur. Penggunaan confusion matriks untuk mengetahui performance algoritma Naive Bayes. Berdasarkan pengujian, penelitian ini menghasilkan 76% dengan accuracy positif sebesar 72,727%, accuracy negatif sebesar 75% dan accuracy netral sebesar 78,947%. Sehingga disimpulkan penggunaan model klasifikasi Naive Bayes dengan fitur seleksi dapat meningkatkan akurasi.Kata kunci: analisis sentimen, seleksi fitur, twitter crawling, naïve bayes, klasifikasi, emosiAbstractCovid-19 pandemic is almost in its second year in Indonesia, the government continues to try to suppress the rate of increase in the transmission of Covid-19 through various media. Socialization and information through social media which is the fastest medium to be conveyed to the public. Various terms are used, such as adapting new habits, social distancing, PSBB to PPKM, thus triggering the public to share opinions on social media. This study analyzes public sentiment regarding the increasing opinion of Covid-19 from twitter. Tweet classification based on positive, negative and neutral classes using Naive Bayes with feature selection. The use of confusion matrix to determine the performance of the Naive Bayes algorithm. BasedThis Research, the results from the sentiment analysis system using the nave Bayes classifier of 76% with positive accuracy of 72.727%, negative accuracy of 75% and neutral accuracy of 78.947%. So it can be concluded that the use of the Naive Bayes classification model with the selection feature can increase accuracy.Keywords: sentiment analysis, fitur selection twitter crawling, naïve bayes, clasification, emotion
Metode Simple Additive Weigting dalam Penerapan Sistem Pendukung Keputusan Seleksi Santri Terbaik TPQ Yayasan Hubbu Ahmad Center
Authors: NULHAKIM LUKMAN , FAUSIYAH NANDA
Published: March 2022

AbstrakProses seleksi santri terbaik pada Yayasan Hubbu Ahmad Center masih belum optimal. Banyaknya data nilai yang harus diolah dan seleksi hasil nilai tertinggi masih dilakukan dengan cara konvesional dengan memilih santri berdasarkan data yang ada kemudian dibuat kesimpulan bahwa santri tersebut mendapat predikat terbaik, tentu hal ini sangat kurang efektif dan tingkat ke akuratan yang dirasa kurang tepat. Dengan metode Simple Additive Weighting (SAW) proses seleksi dilakukan dengan urutan dan kriteria serta perhitungan yang tepat dan sesuai, sehingg sistem seleksi santri terbaik ini dengan tujuan membantu guru dalam menentukan santri terbaik dan tidak terjadi kesalahan. Dalam perancangan ini penulis menggunakan web base PHP sebagai aplikasi perhitungan seleksi santri terbaik dan MySQL sebagai database sistem.  Kata kunci: Santri Terbaik, Mysql, PHP, SAWAbstractThe selection process for the best students at the Hubbu Ahmad Center Foundation is still not optimal. The amount of value data that must be processed and the selection of the highest results is still carried out in the conventional way by selecting students based on existing data and then a conclusion is made that these students get the best predicate, of course this is very less effective and the level of accuracy is felt to be less precise. With the Simple Addtive Weighting (SAW) method, the selection process is carried out with precise and appropriate sequences and criteria as well as calculations, the best student selection system with the aim of helping teachers determine the best students and there are no errors. In this design the author uses a web base PHP as the best student selection application and MySQL as a database system.Keywords: Best Santri, Mysql, PHP, SAW
Analisis Sistem Tanggap Darurat Tumpahan B3 Studi Kasus di Perusahaan Manufaktur
Authors: Pasha Mochamad Ulwan , Soemirat Juli , Deni M Candra Nugraha
Published: March 2022

AbstrakIndustri semakin banyak menggunakan material dan proses yang tergolong berbahaya  yang dikelompokan sebagai bahan berbahaya dan beracun (B3). Setiap proses produksi memiliki risiko terjadinya kecelakaan kerja yang diakibatkan oleh B3 hingga mengakibatkan keadaan darurat yang dapat merugikan secara kesehatan, material, dan finansial. PT X merupakan perusahaan yang bergerak di bidang manufaktur, dengan terdapat 5 proses produksi diantara nya: gudang penyimpanan barang produksi, konstruksi, nailing, assembling, dan finishing. Dalam tahap tersebut terdapat B3 seperti nikel, chromium, asam sulfat, dan solar yang digunakan. Oleh karena itu, perlu dilakukan evaluasi sistem tanggap darurat tumpahan B3 pada PT X, yang terdiri dari manajemen tanggap darurat, sarana dan prasarana tanggap darurat, dan pengelolaan B3 itu sendiri. Evaluasi dilakukan dengan membandingkan kondisi eksisting dengan peraturan diantaranya PermenLHK 74/2019, PermenLH 03/2008, dan beberapa National fire protection association (NFPA). Hasil evaluasi menunjukan nilai penerapan sistem tanggap darurat B3 di PT X sebesar 49,82% dikarenakan terdapat beberapa komponen yang belum tersedia dan beberapa komponen yang tidak sesuai standar. Oleh karena itu diperlukan suatu sistem tanggap darurat tumpahan B3 berupa rencana pengelolaan kedaruratan (RPK), mulai dari merencanakan tindakan pencegahan tumpahan, tindakan pada saat terjadi tumpahan, hingga pada pemulihan pasca tumpahan B3. Kata kunci: Industri, B3, Sistem Tanggap Darurat, rencana pengelolaan kedaruratanAbstractHazardous chemicals are  substances that are classified known as hazardous substances. Production processes using such substances may carry a risk of work accidents caused by them resulting in emergencies that can be detrimental to health, and cause material, and financial losses. PT X is a manufacturing company, with 5 production processes i.e: warehouse storage of production, construction, nailing, assembling, and finishing, where hazardous materials such as nickel, chromium, sulfuric acid, and diesel are being used. Evaluation of hazardous materials spill emergency response system at PT X consisting of emergency response management, facilities and infrastructure, and proper management were conducted by comparing existing conditions with regulations including PermenLHK 74/2019, PermenLH 03/2008, and several National fire protection associations. The results showed that the implementation of these hazardous materials emergency response system at PT X only comply for 49.82% due to lack of some components and some were not in accordance with the exisiting standards. Hence the need for a comprehensive hazardous materials emergency response system in the form of an emergency management plan, starting from planning spill prevention measures, taking action in the event of a spillage to post hazardous materials spill recovery.Keywords: Industry, Hazardous Materials, Emergency Response, Emergency Management Plan