bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Vestibular vs. Somatosensory Rehabilitation on Balance and Quality of Life of Sub-acute Stroke Patients with Vestibular Syndrome
Authors: Kumar Munaish , Sarwar Namra , Imtiaz Khushbakht , Malik Arooj , Choudhry Muneeba Aziz , Inam Aniqa
Published: October 2024

Background: Stroke is one of the most common causes of disability worldwide, affecting millions of people per year, and it has a large burden on health care systems. In the early subacute phase, patients who survive a stroke usually show impairments in balance, often due to sensory and vestibular deficits; this influences their quality of life.

Methods: A double-blind, randomized controlled trial was conducted to assess the effectiveness of vestibular and somatosensory interventions on balance and quality of life in early subacute stroke patients with vestibular syndrome. Fifty-two patients were randomly divided into a vestibular or somatosensory rehabilitation group or a control group receiving usual care. The trial was completed by 49 patients who were evaluated onon the Berg Balance Scale and the Vestibular Quality of Life Questionnaire at baseline and 12 weeks post-intervention.

Results: The study found that both vestibular and somatosensory rehabilitation interventions led to significant improvements in balance, as indicated by the Berg Balance Scale scores, and quality of life, based on vestibular Quality of Life Questionnaire scores, compared to the control group (p<0.05). There was no significant difference between the two intervention groups in terms of their impact on either balance or quality of life outcomes.

Conclusion: Vestibular and somatosensory rehabilitation interventions represent effective strategies for improving balance and quality of life in early subacute stroke patients with vestibular syndrome. These findings underline the importance of including targeted rehabilitation approaches within stroke care protocols to achieve optimal functional outcomes and long-term recovery.

Keywords: Balance, Stroke, Quality of Life, Vestibular Symptoms.
Reimagining Healthcare Delivery: Enhancing Patient-Centric Services in Pakistan Public Hospitals
Authors: Hasan Zaki , Zeerak Syeda , Fatima Humaira , Zubair Tabassum , Munir Amna
Published: October 2024

Background: The study explored the allied health services provided by Karachi public hospitals. Patient engagement, treatment quality, digital marketing efficacy, accessibility, patterns of usage, and satisfaction with health outcomes were the primary areas of interest. With the potential to improve patient experiences and health outcomes, the findings offered recommendations to enhance patient-centered care, service accessibility, and communication strategies.

Methodology: This cross-sectional study focused on the health outcomes in public healthcare facilities. Stratified random sampling and Smart Partial Least Squares (PLS) analysis were used to examine the associations among the variables. The sample-to-variable ratio determined a sample size of 410 for executing Smart PLS regression and correlation analysis.

Results: The study found a robust correlation between factor loadings and demographic traits. Positive relationships between patient utilization, service accessibility, the efficacy of digital marketing, and the quality of care were revealed. Further, the moderation analysis highlighted that empathy was critical in determining patient happiness. The model fit indices showed a good fit, with some minor differences amongst models. The structural equation model results confirmed the crucial role of patient engagement, care quality, and service accessibility in influencing patient utilization.

Conclusion: The study emphasized that patient-provider relationships and moderating factors like empathy helped serve the patients better and positively. These findings underline the significance of holistic methods in promoting patient-centric care delivery and eventually improving healthcare.

Keywords: Digital Marketing Effectiveness, Patient Engagement, Quality of Care Delivery, Service Accessibility and Convenience.
Effects of Multi-modal Rehabilitation Approach in Headache-related Anxiety and Depression
Authors: Khan Rabia , Latif Danish , Shahid Ghousia , Usman Muhammad , Lata Prem
Published: October 2024

Background: A comprehensive, multi-modal rehabilitation that addresses both the physical and mental health aspects of headache disorders has the potential to give more effective relief and improve patients’ overall quality of life. Further studies are required to determine the most beneficial exercise modalities and incorporate them into a comprehensive treatment strategy for headache-related anxiety and depression.

Methodology: A multi-modal rehabilitation was administered for 8 weeks. Participants engaged in 45 minutes of supervised aerobic exercises three times/week. A dry needling session was performed for 30 minutes on the trigger points associated with neck pain, while massage was performed to reduce muscle tension in the head, neck and shoulder regions, lasting for 30 minutes.

Results: The outcome measures assessed at baseline revealed that the pain intensity as measured using VAS was 7.3±1.3, the value of headache impact test (HIT) was 55.3±1.4 and HADS-Anxiety and Depression was 16.32±1.56 and 15.35±1.47 respectively, that was significantly reduced to 3.26±1.25 (VAS), 35.6±1.21 (HIT) and 10.32±1.52 (HAD-A) and 9.56±1.2 (HAD-D) respectively after 8 week of multi-modal rehabilitation.

Conclusion: The findings of this study demonstrated that a multi-modal rehabilitation intervention, comprising aerobic exercises, dry needling, and massage therapy, significantly reduces headache-related pain intensity, anxiety and depression in patients with primary headache disorders.

Keywords: Anxiety, Depression, Exercise, Headaches.
Enhancing Continuity of Physiotherapy Care: Investigating the Impact of Missed Follow-up Appointments in Outpatient Settings
Authors: Malik Arooj , Gelani Sania , Hashmi Syeda Fatima , Safeer Dr. Anum , Vansi Jai , Ghafoor Dr. Asma
Published: October 2024

Background: Physiotherapy is essential in managing chronic diseases in musculoskeletal, neurological and cardiovascular domains. These conditions have high morbidity rates and hence need therapeutic interventions that enhance the quality of life. However, poor adherence to review appointments diminishes treatment effectiveness and healthcare productivity. Evidence from developed countries reveals varying missed appointment (MA) rates, thereby calling for targeted treatments embedded in contextual factors.

Methods: This was a retrospective study using clinic data to identify MA rates and associated variables that included age, gender, and residential origins. The effect of each variable on appointment adherence was investigated. An intervention plan was designed to reduce MA through appointment reminders and patient education. Incentives were also foreseen. Descriptive statistics, Pearson’s correlation and cost-benefit analysis was conducted using SPSS version 23.

Results: The rate of MA was 22% initially, significantly reducing to 12% after the intervention (p<0.001). The demographic variables significantly relating to appointment adherence were age group and residential location (p<0.001, 0.012) respectively. Seasonality and referral sources played their role in attendance patterns, which align with earlier studies on healthcare use determinants.

Conclusion: This study provides deep insights from physiotherapy appointment adherence in Pakistan and depicts successful measures for reducing MAs and improving treatment delivery. The findings represent the values of patient-centred treatments, which result in a better functional outcome for patients, with a smooth running of clinic operations.

Keywords: Appointments, Follow-up, Physiotherapy, Records.
Effect of Strengthening versus Neuromuscular Training on Pain and Functionality in Individuals with Patellofemoral Pain Syndrome
Authors: Bhutto Mazhar Ali , Nazir Amman Ullah , Katta Ravi Kumar , Rani Mahnoor , Talha Dr. Muhammad , Sheikh Naseebullah
Published: October 2024

Background: Patellofemoral pain syndrome (PFPS) is a disorder that commonly affects young adults and athletes and causes disability in physical function and quality of life. Therefore, effective management strategies, including but not limited to exercise interventions, are necessary to relieve symptoms and improve outcomes.

Methods: A total of 45 PFPS patients were randomly assigned to either a group receiving strengthening exercises (EG 1) and neuromuscular training (EG 2) combined with conventional Physical Therapy, or a control group (CG) that only received conventional Physical Therapy. The interventions were conducted 3 times/week for 4 weeks. Kujala AKPS and KOOS scores were measured before and after the intervention period.

Results: The AKPS and KOOS scores improved significantly in all the groups after the interventions (p<0.001). The greatest improvement was observed in the EG 1 group, followed by the EG 2 group, and the least improvement was observed in the CG. However, a significant time, group, and interaction effect was demonstrated regarding AKPS (p<0.05) and KOOS (p<0.05) through repeated measures of ANOVA.

Conclusion: The findings of the study indicate that strengthening exercises are more effective than neuromuscular training and conventional therapy for treating PFPS. This study provides consistent evidence to support the use of targeted exercise interventions to improve clinical outcomes and quality of life for individuals with PFPS.

Keywords: Exercise, Patellofemoral Pain Syndrome, Physical Function, Quality of Life.
Efficacy of Post-Isometric Relaxation vs. Sustained Stretching for Improving Cervical Spine Mobility in Upper Cross Syndrome-A Randomized Controlled Trial
Authors: Kumar Dr. Vinod , Tanveer Erum , Ahmed Dr. Hamza , Kumar Dr. Sumeet
Published: October 2024

Background: Upper Crossed Syndrome (UCS) is a common musculoskeletal disorder characterized by muscle imbalance in the head and shoulder areas, often exacerbated by poor posture. Muscle Energy Technique (MET), including Post-Isometric Relaxation (PIR) and sustained stretching, is commonly used to alleviate symptoms associated with UCS.

Methodology: This randomized controlled trial compared the efficacy of PIR versus sustained stretching in reducing muscle tightness of the upper trapezius and levator scapulae muscles among 30 participants at Al-Sehat Rehabilitation Centre, Karachi, Pakistan. Pain intensity was assessed using the Numeric Pain Rating Scale (NRS), and cervical range of motion (ROM) was measured with an inclinometer.

Results: PIR and sustained stretching significantly reduced pain and improved cervical ROM. PIR showed superior pain reduction, while sustained stretching enhanced ROM, particularly in left rotation and lateral flexion.

Conclusion: PIR and sustained stretching are effective treatments for managing UCS-related symptoms. PIR excels in pain management, whereas sustained stretching enhances cervical ROM. Clinicians should consider these findings when designing treatment protocols for UCS.

Keywords: Disability, Pain Management, Range of Motion, Upper Cross Syndrome.
The effect of Capparis spinosa extract on some immunological and physiological variables of mice
Authors: Intisar Masier Abd  , Nuha Majeed Farhan  , Lubab Mohammed Awad
Published: October 2024

Background The pungent taste and numerous health advantages of the caper plant are not to be overlooked. Thanks to its high vitamin content—including B12, niacin, vitamin K, vitamin A, vitamin E, and fiber—it finds widespread usage as both a culinary seasoning and a medicinal herb. Methodology The Soxhlet device was the most efficient and effective way to isolate the plant's active organic ingredient crude.  I ground the plant into a powder using a blender. Then, I added 250 mL of ethanol and added 95% after extraction. I extracted the plant within 24 hours and concentrated the mixture using a rotary evaporator. Finally, I frozen it at -20 ° until I needed it. The mice were housed in sanitary cages that met their nutritional, thermal, and ventilation needs. The experiment did not begin until the mice had been allowed to acclimate for one week without treatment. Result The results presented here appear to be descriptive statistics for a number of physiological characteristics measured in mice treated with varying concentrations of Capparis spinosa extract (control, 10%, and 20%). Haemoglobin (Hb), packed cell volume (PCV), red blood cell count (RBC), white blood cell count (WBC), and the total count for each therapy group are the variables that are being considered. In order to compare the control group with the groups treated with varying doses of Capparis spinosa extract, this data sheds light on the central tendency and variability of physiological variables under different treatments. The results showed an increase in some blood variables compared to the control. There is also an increase in the number of white blood cells, which enhances the increase in the first line of defense against pathogenic organisms.
Vertretene Organe
Authors: Klatt Matthias , Weber Max
Published: October 2024

Der Deutsche Bundestag hat kürzlich erstmals konkrete Gesetzesentwürfe zur Absicherung des Bundesverfassungsgerichts beraten. Nachdem das Plenum Vorschläge zur Änderung des Grundgesetzes sowie des Bundesverfassungsgerichtsgesetzes diskutiert hat, ist nun der Rechtsausschuss damit befasst. Ein Blick auf die geplanten Regelungen lässt jedoch Unklarheiten hinsichtlich der Zuständigkeitsverteilung im Rahmen des vorgesehenen Ersatzwahlmechanismus erkennen, die dringend behoben werden sollten.
Migración. Retos actuales
Authors: López Velarde-Campa Jesús Armando
Published: October 2024

El fenómeno migratorio ha sido una constante en la historia de la humanidad, motivado por diversas razones como la búsqueda de oportunidades laborales, la reunificación familiar, el estudio, o la necesidad de escapar de conflictos, persecuciones, desastres naturales y los efectos del cambio climático. Según estimaciones de la ONU, en 2020 había cerca de 281 millones de migrantes internacionales, cifra que ha crecido debido a situaciones de crisis y desigualdad. En América Latina, se han vivido momentos clave de migración relacionados con la llegada de europeos, crisis internas, movilizaciones entre países fronterizos y, más recientemente, la globalización. Sin embargo, el fenómeno migratorio se enfrenta a desafíos derivados de las desigualdades estructurales y la explotación laboral en los países receptores, lo que genera discriminación y un entorno de inseguridad para los migrantes. A nivel global, el texto "Migración. Retos actuales" examina los principales desafíos que enfrenta la migración contemporánea, incluyendo la protección de los derechos humanos de los migrantes, la jurisprudencia de la Corte Interamericana de Derechos Humanos, el impacto del cambio climático, y los conflictos armados como causas de desplazamiento forzado. El libro destaca la necesidad de un enfoque integral que considere tanto las causas como las consecuencias de la migración, así como la cooperación internacional para promover políticas inclusivas y basadas en derechos humanos. La obra subraya también la importancia de instituciones y organismos internacionales como ACNUR y OIM, que juegan un papel crucial en la protección y asistencia humanitaria para los desplazados y refugiados.
ENTREVISTA
Authors: Dr. Saulo Ribeiro dos Santos
Published: October 2024

ENTREVISTA 
Dr. Saulo Ribeiro dos SantosSecretário Municipal de Turismo de São Luís.
Association of Intellectual and Developmental Disabilities With Worse Outcomes After Surgical Treatment of Cancer
Authors: Resende Vivian , Woldesenbet Selamawit , Katayama Erryk , Munir Muhammad Musaab , Lima Henrique Araújo , Khalil Mujtaba , Rawicz-Pruszyński Karol , Khan Muhammad Muntazir Mehdi , Waqar Usama , Mavani Parit , Endo Yutaka , Pawlik Timothy M.
Published: October 2024

Background: Patients with intellectual and developmental disabilities (IDD) face unique challenges resulting in disparities in their health care. We sought to define the effect that IDD had on achievement of a “textbook outcome” (TO) following a cancer operation among a nationally representative cohort of patients. Methods: Data on patients who underwent surgery for a malignant indication, including lung, breast, liver, biliary tract, pancreas, and colorectal, between 2014 and 2020 were extracted from the 100% Medicare Standard Analytical Files database. The association of IDD with TO (defined as the absence of postoperative complications, extended length of stay, 90-day readmission, and 90-day mortality), expenditures, and discharge status was assessed using multivariable logistic regression. Results: Among 500,472 Medicare beneficiaries, 4,326 (0.9%) with IDD had a cancer diagnosis (breast, n=481; lung, n=419; hepatobiliary, n=194; pancreas, n=145; colorectal, n=3,087). Although overall incidence of TO was 50.5%, patients with IDD were less likely to achieve a TO than those without (37.1% vs 50.6%, respectively; odds ratio [OR], 0.50; 95% CI, 0.46–0.53; P<.001). On multivariable regression, patients with IDD had higher odds of a postoperative complication (OR, 1.53; 95% CI, 1.43–1.64), extended length of stay (OR, 2.06; 95% CI, 1.93–2.21), 90-day readmission (OR, 1.15; 95% CI, 1.07–1.24), 90-day mortality (OR, 1.90; 95% CI, 1.70–2.13), and discharge to a skilled nursing facility (OR, 4.28; 95% CI, 3.97–4.62) (all P<.001). Conclusions: Patients with IDD had a much lower chance of a postoperative TO, as well as discharge to a nonhome setting. The data highlight the need to improve the care of patients with IDD to assure equitable oncologic surgical care.
Synthesis of biocompatible hydroxyapatite from quail eggshell, oyster shell, and periwinkle snail shell
Authors: Suandork Phurinart , Hongsuwong Marchin
Published: October 2024

This study focuses on the synthesis of hydroxyapatite (HA, Ca10(PO4)6(OH)2) from calcium carbonate (CaCO3)-rich quail eggshells, oyster shells, and periwinkle snail shells (Filopaludina bengalensis) through the use of the wet precipitation method. The methodology involved calcining the shell waste to convert CaCO3 to calcium oxide (CaO), undergoing hydration, and reacting with phosphoric acid (H3PO4) to synthesize HA. The results indicated that periwinkle snail shells had the highest percent yield of HA at 92.12%, followed closely by quail eggshells at 92.01%, and oyster shells at 73.65%. For producing CaO, oyster shells provided the highest percent yield of CaO at 103.72%, followed by quail eggshells at 98.6% and periwinkle snail shells at 92.09%. The synthesized HA exhibited high biocompatibility, which is crucial for its potential applications in medical fields such as bone replacement and regeneration. The X-ray diffraction (XRD) analysis confirmed the successful synthesis of high-quality HA, with characteristic peaks indicative of excellent crystallinity and purity and near identicality to the standard XRD pattern of HA of ICDD 9-432 and the XRD pattern of successfully synthesized HA in other studies, indicating high biocompatibility. The research highlights the potential of recycling food waste, specifically shell waste, into valuable biomaterials. This not only addresses environmental concerns but also supports sustainable practices in the food industry. Moreover, the study contributes to advancements in biomaterials for medical applications, emphasizing the viability of utilizing organic waste for high-value products. By transforming food waste into useful medical materials, this research offers promising solutions for waste management and resource utilization, particularly within Thailand's ecological and industrial framework.
AVALIAÇÃO DA QUALIDADE DE COMPRIMIDOS DE HEMITARTATO DE ZOLPIDEM 10 MG COMERCIALIZADOS NA CIDADE DE ITACOATIARA-AM
Authors: Afilhado Juciane Carvalho , Colares Eldon Carlos dos Santos , Santos Mateus Feitosa , Da Silva Anyele Ramos , Souza Sabrina dos Santos
Published: October 2024

O desenvolvimento tecnológico e de qualidade de medicamentos deve seguir diversos padrões de qualidade para garantir que um determinado fármaco tenha sua atividade farmacológica evidenciada. Dentre os medicamentos comercializados está o Hemitartarato de Zolpidem que pertence a classe das imidazopiridinas usado no tratamento da insônia. Os comprimidos revestidos necessitam obedecer a critérios de controle de qualidade como: doseamento, dureza, peso médio, desintegração e dissolução. O objetivo deste trabalho foi avaliar a qualidade dos comprimidos de Hemitartarato de Zolpidem comercializados em Itacoatiara através de ensaios farmacopeicos. Os ensaios foram realizados na UFAM de Itacoatiara e Fametro Manaus. Os resultados obtidos apresentaram valores dentro do que é estabelecido pela Farmacopeia Brasileira.
ATIVIDADE ANTIDIABÉTICA DE FLAVONOIDES: REVISÃO INTEGRATIVA
Authors: Da Silva Anyele Ramos , Afilhado Juciane Carvalho , Colares Eldon Carlos dos Santos , Santos Mateus Feitosa , Souza Sabrina dos Santos
Published: October 2024

O diabete mellitus é caracterizado por ser uma doença crônica decorrente de um nível elevado de glicose no sangue (hiperglicemia), que ocorre quando o organismo não produz o hormônio insulina suficiente. Um dos métodos naturais para controle do diabetes é o uso de produtos bioativos ricos em substâncias conhecidas como flavonoides. Este estudo consiste em uma revisão do tipo integrativa e descreve acerca da a atividade antidiabética dos flavonoides. Foram selecionados 14 artigos publicados no período de 2000 a 2018. Em todos os trabalhos selecionados os flavonoides apresentaram-se ativos na diminuição de índices glicêmicos e no tratamento do diabetes.
Explorando la empleabilidad en Nayón: tendencias y desafíos actuales
Authors: Sanguna Carrera Katherine Lorena , Achig Pillajo Jonathan Alexander
Published: October 2024

El presente artículo se enfocó en determinar el estado de la empleabilidad en la Parroquia de Nayón, provincia de Pichincha, Ecuador, con el objetivo de proponer recomendaciones para mejorar las oportunidades de empleo en la comunidad en donde se analizó un contexto de crecimiento demográfico y económico, impulsado por la cercanía con Quito, que ha llevado a un aumento en la actividad económica local y, consecuentemente, a una mayor competencia en el mercado laboral. La parroquia tiene una economía diversa, con sectores como el comercio minorista, la agricultura, la construcción, y los servicios, donde se resaltó la importancia de la educación y la formación profesional en la empleabilidad de la población, ya que existe un notable aumento de profesionales en la zona, aunque persiste una tendencia hacia empleos que requieren menor cualificación para comprobar lo anterior se utilizó una metodología aplicada se divide en 3 fases principales: recopilación de la información, fase 2: procesamiento e interpretación de la información, fase 3: creación del modelo integral. Como recomendaciones, se sugirió promover el turismo, apoyar a emprendedores locales, y desarrollar programas de capacitación ajustados a las necesidades del mercado laboral.
Estudio exploratorio del uso de las TIC en la modalidad de educación M-learning (Mobile Learning)
Authors: Espinosa Cevallos Paola Alejandra
Published: October 2024

El modelo de aprendizaje basado en el uso de dispositivos móviles o M-learning se presenta como una de las tecnologías emergentes con un importante impacto en los procesos educativos presentes y futuros, debido que, la facilidad de acceso a la información en cualquier momento y en cualquier lugar permite desarrollar una experiencia de aprendizaje flexible y personalizado en la que el contexto es importante. El M-learning es el resultado de una combinación del E-learning con los dispositivos móviles, con la capacidad de propiciar experiencias educativas en cualquier situación, lugar y momento, trasladando los procesos de aprendizaje a una nueva dimensión al poder cubrir necesidades educativas urgentes con movilidad y alta interactividad. En base a lo anterior se desarrolló la presente revisión bibliográfica con el objetivo de estudiar el uso de las TIC en la modalidad de educación M-learning, permitiendo dejar en evidencia el trabajo investigativo realizado en esta área, así como el conocimiento de los aportes de esta metodología a los procesos educativos, los cuales siempre están orientados a obtener un aprendizaje significativo, que trascienda a la vida cotidiana, profesional y laboral de los estudiantes.
Necrólise Epidérmica Tóxica (NET): Relato de caso
Authors: Pozzer Mocellin Diana , Carraro Merlos Priscila Gabriella , Merlos Fernando
Published: October 2024

A síndrome de Steven Johnson (SSJ) e Necrólise Epidérmica Tóxica (NET) são desordens do sistema de hipersensibilidade à exposição de fármacos. Na totalidade sua patologia é desconhecida, mas com envolvimento do sistema imune e dos queratinócitos na junção dermo-epidérmica, resultando assim do desprendimento cutâneo e formação de bolhas. Para um desfecho favorável é necessário uma rápida detecção do agente desencadeante e sua suspensão ao mesmo tempo que medidas terapêuticas devem ser feitas em ambiente de terapia intensiva ou ala de grandes queimados. O presente artigo expõe um relato de caso de uma paciente com necrólise epidérmica tóxica, desencadeada por uso de um  medicamento e seu desfecho,  com o propósito de demonstrar a importância, de uma rápida detecção e um suporte adequado, preferencialmente em terapia intensiva, assim como foi observado no relato de caso apresentado. Sendo assim, as síndromes SSJ e NET são verdadeiras emergências médicas, demonstrando a importância no rápido diagnóstico e início precoce de tratamento, com o intuito de diminuir a morbimortalidade.
Tratamento de Resgate do Cálculo Renal Gigante com Pielolitotomia Videolaparoscópica Após Nefrolitotripsia Percutânea
Authors: Chaves Ramos Luíza , De Castro Almeida Abílio , Carvalho Ribeiro Daniel , Antunes Garcia Marcondes , Mendes Cupertino Yara
Published: October 2024

A nefrolitíase é uma condição comum, de etiologia multifatorial, influenciada por fatores genéticos, metabólicos e ambientais, e com uma apresentação clínica que pode variar desde quadros assintomáticos até sintomas clássicos como dor lombar intensa e hematúria. O tratamento abrange desde abordagens conservadoras, como a terapia expulsiva clínica, até técnicas minimamente invasivas e procedimentos cirúrgicos. Este relato de caso descreve o manejo de uma paciente do sexo feminino, portadora de cálculo renal gigante, com apresentação clínica de infecção urinária de repetição e dor lombar. Após diagnóstico por tomografia computadorizada, optou-se pela pielolitotomia videolaparoscópica devido à dimensão significativa do cálculo. O procedimento transcorreu sem complicações, resultando na remoção completa do cálculo e alívio dos sintomas.
INDIVIDUAL FORAMINIFERAL ANALYSES: A REVIEW OF CURRENT AND EMERGING GEOCHEMICAL TECHNIQUES
Authors: Fehrenbacher Jennifer S. , Hupp Brittany N. , Branson Oscar , Evans David , Foster Gavin L. , Glock Nicolaas , Thirumalai Kaustubh , Wycech Jody
Published: October 2024

The trace element (TE) and isotopic composition of calcareous foraminifera has been invaluable in advancing our understanding of environmental change throughout the geological record. Whereas “bulk” geochemical techniques, typically requiring the dissolution of tens to hundreds of foraminiferal tests for a single analysis, have been used for decades to reconstruct past ocean-climate conditions, recent technological advances have increased our ability to investigate foraminiferal geochemistry from an individual test to a micron-scale domain level. Here we review current and emerging techniques and approaches to studying the trace element and stable isotope geochemistry of individual foraminifera (i.e., individual foraminiferal analyses or “IFA”), covering spatial scales including whole-test analysis, intratest spot analysis, and cross-sectional chemical mapping techniques. Our discussion of each technique provides an overview of how the specific analytical tool works, the history of its usage in foraminiferal studies, its applications, considerations, and limitations, and potential directions for future study. Lastly, we describe potential applications of combining multiple IFA techniques to resolve key questions related to paleoceanography, (paleo)ecology, and biomineralization, and provide recommendations for the storage, dissemination, and transparency of the vast amounts of data produced through these methods. This review serves as a resource for budding and experienced foraminiferal geochemists to explore the wide array of cutting-edge approaches being used to study the geochemical composition of modern and fossil foraminifera.
METODA KONSOLIDACE DEGRADOVANÝCH HEDVÁBNÝCH TEXTILIÍ POMOCÍ FIBROINU A EGDE
Authors:   Muzeum hlavního města Prahy, Řeřichová Jaroslava , Koubová Pavlína ,   Muzeum hlavního města Prahy
Published: October 2024

Studie popisuje experiment postavený na čínské metodě konsolidace degradovaného hedvábí pomocí fibroinu a etylen glykol diglycidyl etheru (EGDE), publikované v roce 2021 na konferenci ICOM – CC v Pekingu. Výhodou tohoto ošetření (oproti dosud používaným kon- solidačním prostředkům) je aplikace látky, která má chemické složení shodné s hedvábím. Úvodní fáze naší studie měla ověřit uvedený pos- tup aplikace fibroinu a zhodnotit využití metody v muzejním prostředí. Postup nanášení fibroinu i EGDE byl nejprve zkoušen na referenčních hedvábných vzorcích, poté byly vybrány vhodné historické předměty ze sbírek Muzea hlavního města Prahy, které byly ošetřeny fibroinem, čištěny a adjustovány. Stav předmětů byl zdokumentován před i po nanesení konsolidačního prostředku a také po procesu čištění. K vyhodnocení byla využita optická mikroskopie a organoleptická zkouška. Experiment je základem pro dlouhodobější projekt, ve kterém se zaměříme na další možnosti a využití metody.
CMV hepatiti ilişkili portal ven trombozu “olgu sunumu”
Authors: Kilic Tekin Merve , Erbağcı Enes
Published: October 2024

Sitomegalovirüs enfeksiyonu nadiren portal ven trombozuna yol açabilir. Vakamızda sunduğumuz gibi, son yıllarda bağışıklığı yeterli bireylerde Sitomegalovirüs ilişkili tromboz vakaları dikkat çekmektedir. 31 yaşında erkek hastanın iş başvurusu öncesi rutin taramalarında alanin aminotransferaz ve aspartat aminotransferaz düzeylerinde yükseklik tespit edildi. Aktif yakınması yoktu. Portal venöz doppler incelemesinde sağ portal ven içerisinde lümeni subtotal oklüde eden ekojen trombüs materyalleri tespit edildi. Anti-CMV IgM ve IgG pozitif, trombozu açıklayacak diğer tetkikler normaldi. Anti-CMV IgG düşük avidite, CMV PCR 137 kopya/mL idi ve akut Sitomegalovirüs hepatitine sekonder portal ven trombozu olarak değerlendirildi. Antiviral tedavi uygulanmaksızın, antikoagülan tedavi ile transaminazlar normal düzeye geriledi. Kontrol portal venöz doppler incelemesinde trombüsün çözüldüğü tespit edildi. Portal ven trombozu nedeni araştırılırken hasta asemptomatik olsa da Sitomegalovirüs infeksiyonu akla gelmelidir. Sitomegalovirüs hepatiti varlığında asemptomatik vakalarda portal ven trombozu yönünden inceleme gerekebilir.
(DES)ACESSO À JUSTIÇA, OBSTÁCULOS E ALTERNATIVAS PARA A EFETIVIDADE
Authors: MAZZINI CRISTIANO
Published: October 2024

O acesso à justiça como direito constitucional está posicionado como direito fundamental e a dificuldade em sua implementação, por parte do usuário, é um dos maiores entraves enfrentados no Brasil, constituindo-se em grave obstáculo a concretização da justiça, além de descrença e inegável obstáculo ao acesso à justiça. Por essa razão, são estabelecidas várias causas que obstaculizam o acesso, a maioria relacionada a questões monetárias, sendo, pois, a pobreza a principal a trazer uma série de óbices acessórios que levam a criação de uma demanda reprimida, ou seja, ao “desacesso”. Nesse sentido, o objetivo do trabalho foi apresentar os principais obstáculos ao acesso e apresentar, de forma inicial, algumas premissas que contribuirão com sua efetivação. Para isso, foi realizada pesquisa bibliográfica e documental, além do uso de compreensões provenientes da experiência profissional. A conclusão indica que para tornar o acesso à justiça eficiente, ou seja, para lhe garantir implementação, principalmente nos casos em que os valores econômicos envolvidos são de pequena monta, deverá existir investimento em técnicas alternativas à judicialização convencional, evitando-se a heterocomposição, em prol da autocomposição e o uso da tecnologia.
The Role of Business Incubators in Encouraging Maritime Technology Start-up Innovation
Authors: Yusup Muhammad Firdaus Bin
Published: October 2024

This study examines the critical role of business incubators in driving innovation in maritime technology start-ups. With the growing need for innovative technology solutions in the maritime industry, business incubators have emerged as a key catalyst in developing and introducing new ideas to the market. The study used a qualitative approach, involving in-depth interviews with 30 stakeholders, including start-up founders, incubator managers, and maritime industry experts. The results showed that business incubators provide critical support in the form of access to funding, expert mentoring, research and development facilities, and extensive industry networks. The findings also revealed that incubators that focus on the maritime sector are more effective in helping start-ups overcome industry-specific challenges. The study highlights the importance of collaboration between incubators, the maritime industry, and educational institutions to create an ecosystem that supports innovation. Implications of this study include recommendations for policymakers and industry players in designing more effective incubation programs to drive maritime technology innovation.
Étude de la mort fœtale in utero à Lubumbashi, République Démocratique du Congo
Authors: Mpoy Charles Wembonyama , Katembo Barry Mukwarari , Missumba Willy Kakozi , Kinenkinda Xavier K.
Published: October 2024

Introduction. La mort fœtale in utéro (MFIU) constitue un véritable problème en obstétrique avec une fréquence élevée dans les pays en développement. Le présent travail s’est fixé comme objectifs de déterminer la fréquence de mort fœtale in utero à l’hôpital général de référence provincial Jason Sendwe, de décrire le profil épidémio-clinique des accouchées et d’identifier les étiologies probables. Matériel et méthodes. Il s’agit d'une étude descriptive transversale avec mode de récolte prospectif, portant sur 63 accouchements des fœtus mort in utero, des grossesses monofœtale et d’âge gestationnel supérieur à 22 semaines d’aménorrhées, réaliser au cours de la période allant du 1er janvier au 31 décembre 2021 à la maternité de l’hôpital Jason Sendwe de Lubumbashi (RDC). Les paramètres sociodémographiques, anamnestiques, cliniques, obstétricaux et fœto-annexiels ont été étudiés. Résultats. La prévalence de la MFIU était de 4%. La moyenne d’âge des accouchées était de 29,5 ± 6,0 ans et la parité moyenne était de 3,5 ± 1,6 enfants. La plupart des accouchées n’étaient pas instruites (57,1%). L’arrêt des mouvements fœtaux actifs était le motif de consultation le plus fréquent (55,6%) et la majorité des accouchées n’avaient pas suivi de consultations prénatales (52,4%). L’âge gestationnel moyen était de 34,6±4,9 SA et la moitié de grossesses (50,8%) étaient âgées de moins de 33 SA. L'éclampsie et l’hématome retro-placentaire venaient en tête des étiologies (avec chacun 17,5%). La psychose puerpérale était la complication la plus retrouvée avec 9,5% et 6 accouchées (9,5%) étaient décédées. Plus de la moitié (53,97%) des morts-nés avaient un poids de naissance inférieur à 2500 grammes et la macération fœtale était noté dans 39,7% des cas. Conclusion. Le dépistage des facteurs de risque de MFIU et un suivi rapproché de la grossesse en se basant sur le profil maternel et fœto-annexiel pourraient contribuer à diminuer la fréquence de cette mortalité fœtale. Mots-clés : Mort fœtale in utéro, Profil épidémio-clinique, Fréquence, Lubumbashi.
Patellar Tendon Reconstruction Using Hamstring Graft: A Case Report
Authors: - Dr Shripad Joshi , - Dr Andela Veerendra , - Girish Gadekar
Published: October 2024

Background: Patellar tendon ruptures presenting in a chronic setting are rare events that impose technical surgical challenges due to proximal retraction of the patella, quadriceps muscle atrophy and contracture, and peripatellar adhesions. Various reconstruction techniques have been described using different grafts and fixation methods; however, there is a paucity of reported out- comes and there is no consensus on standard of care.
Indications: The patient is a young female of 18yrs who presented with a history of trauma to right knee and was diagnosed with chronic patellar tendon tear. The patient was indicated for patellar tendon reconstruction with autologous hamstring tendon graft due to chronicity of the injury.
Method: Patellar tendon reconstruction using hamstrings graft and fixing with anchor suture and interference screw.
Result: Achieving normal patella tendon height and complete range of motion with restoration of extensor mechanism of knee.
Conclusion: Knee extensor mechanism disruptions necessitate prompt surgical correction. In patients with poor tendon quality and/or a history of knee arthroplasty, primary repair should be supplemented with autograft or allograft. Early repairs yield better results than late interventions, which necessitate intricate reconstructions to reestablish the extensor mechanism's continuity. Achieving early osteointegration of the graft is important in case of tendon reconstructive procedures such as in this case as it leads to better outcomes in terms of rehabilitation and early progress to daily activities.
Keys Words: tendon injuries, patellar tendon reconstruction, chronic patellar tendon tear, hamstring graft, hamstring tendon autograft, interference screw
Blockchain in Supply Chain Management: Enhancing Transparency, Efficiency, and Trust
Authors: - Nahid Khan , - Sarowar Hossain , - Umesh Khadka , - Shifa Sarkar
Published: October 2024

Supply chain management has become an area of focus as organizations around the world work to leverage blockchain technology to increase supply chain visibility, productivity, and reliability. As a novel approach to innovation, this paper aims at assessing whether or not blockchain technology could help overcome problems that have attributed lack of consensus between SCM and its stakeholders including, inadequate information flow, complex logistics, ad inadequate inter-organizational trust. As such, using scientific data I investigate how innovations built on the blockchain enhance efficiency, contain costs, and create instant permanent transparency, including in the supply chain. The research methods include a literature search and analysis, calculations of blockchain benefits in relation to the most important SCM indicators: transaction time, cost cutting, and transparency of suppliers. From our research, it can be suggested that advanced use of blockchain results in improved efficiency by around 20-25% of OM costs, while the error rate will be decreased up to 30%. In addition, by enhancing the history of each product, blockchains decrease fraud rates in high-risk sectors, including the pharmaceutical marketplace, by a half. These findings emphasize the positive impact that blockchain implements to alter the supply chain by promoting trust between the chain’s participants and allowing for secure transfer of necessary information. This research helps to complete the existing literature by giving concrete information about blockchain’s efficiency in the real business environment which could be useful for those companies and government agencies which are aiming to implement blockchain-based solutions in supply chain management. Finally, the ethical issues and implications related to the practical realization of blockchain in SCM are highlighted and analyzed with the help of corresponding recommendations.
The mechanism of using the geographic information system in detecting unsafe spaces in the municipal areas of big cities (Investigation of unsafe places in the city of Dallas, Texas, USA)
Authors: Mehdi Norouzian Mohammad , Gheitarani Nima , Heidarian Najmeh , Safaei-Mehr Mahboobe , Amin Gheitarani Mohammad
Published: October 2024

For a long time, identifying the environmental and spatial factors of crime and trying to eliminate these factors or reduce their effects has been known as the most important way to increase safety and prevent the occurrence of anomalies. Because social anomalies, no matter how they happen to humans, have a place and place and time characteristics. Which distinguishes these behaviors from each other. Surveys show that some urban spaces have a higher crime rate due to their physical, social, and economic characteristics; a city is a collection of special mutual narratives that originate from the role and context of its internal institutions. Therefore, without providing a subjective definition, we accept the existence of the city based on objective characteristics, that is, the quality of the structure of the society and its economic and administrative role, not just the population quantity. Also, some thinkers have provided a comprehensible definition of urban space "Urban space is an organized, decorated, and orderly structure for human activities". Part of human actions and activities take place in place and space, and according to Anthony Giddens, "space is a physical set for social interactions". And on the contrary, some spaces prevent and prevent crimes from being committed inside them. On the other hand, research has proven that criminals often make rational choices when committing crimes and look for the simplest, least dangerous, and most suitable opportunities and conditions in place and time to commit crimes.
PERBANDINGAN PEMBERIAN REBUSAN DAUN SIRIH MERAH DAN REBUSAN DAUN BINAHONG TERHADAP PENYEMBUHAN LUKA PERINEUM PADA IBU POSTPARTUM DI TPMB D KABUPATEN GARUTTAHUN 2024
Authors: Priyanti Decy , Hanifa Fanni , Pangestu Gaidha Khusnul
Published: October 2024

Berdasarkan laporan Dinas Kesehatan Kabupaten Garut, kejadian ruptur perineum mencapai 61% dari jumlah ibu yang melahirkan sementara di Puskesmas Citeras pada tahun 2022 terdapat 237 kasus ibu nifas (28,7%) yang mengalami luka perineum dari 823 ibu bersalin. Dampak yang terjadi apabila penyembuhan luka terhambat dapat menimbulkan banyak permasalahan diantaranya sub involusi uterus. Upaya untuk mencegah infeksi luka perineum dapat dilakukan melalui terapi farmakologis dan nonfarmakologis. Tujuan penelitian ini untuk mengetahui perbandingan pemberian rebusan daun sirih merah dan rebusan daun binahong terhadap penyembuhan luka perineum pada ibu postpartum. Metode penelitian ini menggunakan penelitian kualitatif dengan pendekatan studi kasus. Kegiatan ini dilakukan pada 2 orang ibu nifas yang mengalami luka perineum. Pemberian rebusan sirih merah dan rebusan daun binahong sama-sama efektif dalam penyembuhan luka perineum dengan skor luka yang sama yaitu sebelum diberikan intervensi sebesar 6 menjadi 0 sesudah diberikan intervensi selama 5 hari sehingga dapat disimpulkan bahwa tidak terdapat perbedaan efektivitas antara rebusan daun binahong dan rebusan daun sirih merah yang sama-sama efektif terhadap penyembuhan luka perineum pada ibu nifas. Diharapkan hasil penelitian ini dapat membantu dalam meningkatkan pengetahuan keluarga atau masyarakat tentang pengobatan dan perawatan luka perineum dengan menggunakan air rebusan daun binahong dan daun sirih merah dengan cara membasuh atau membersihkan luka sehingga masyarakat dapat melakukannya secara mandiri sesuai dengan arahan
Peningkatan Karakter Disiplin dan Tanggung Siswa Kelas 5 SD Negeri 1 Bedali Lawang melalui Kegiatan Pembiasaan
Authors: Fauziyah Zahrotul , Indawati Ninik , Nawaji Nawaji
Published: October 2024

Pendidikan karakter di Indonesia terus dikembangkan guna memperbaiki mutu pendidikan. Tujuan penelitian untuk menganalisis penerapan kegiatan pembiasaan siswa kelas 5 SD Negeri 1 Bedali Lawang untuk meningkatkan karakter disiplin dan tanggung jawab. Permasalahan yang terjadi adalah menurunnya karakter disiplin dan tanggung jawab. Penelitian ini menggunakan pendekatan kualitatif. Penelitian dilakukan di SD Negeri 1 Bedali Lawang. Subjek dari penelitian ini adalah siswa kelas 5 SD Negeri 1 Bedali Lawang. Jenis dan sumber data pada penelitian ini adalah data primer dan data sekunder. Teknik pengumpulan data yang digunakan adalah wawancara, observasi, dan dokumentasi. Hasil penelitian menunjukkan bahwa untuk meningkatkan karakter disiplin dan tanggung jawab pada siswa kelas 5 SD Negeri 1 Bedali Lawang adalah dengan penerapan kegiatan pembiasaan. Penerapan pembiasaan yang dilakukan pada siswa kelas 5 SD Negeri 1 Bedali Lawang adalah pembiasaan rutin, pembiasaan spontan, pembiasaan terprogram, dan pembiasaan keteladanan. Kendala yang dihadapi dalam penerapan kegiatan pembiasaan diantaranya terbatasnya kontrol dari guru, faktor keluarga terutama orang tua, faktor lingkungan, serta faktor kemajuan teknologi. Tolak ukur keberhasilan dari penerapan pembiasaan adalah siswa mulai disiplin dalam waktu, tingkah laku, dan peraturan. Siswa menjadi lebih bertanggung jawab terhadap setiap perbuatan yang dilakukan, menggunakan waktu secara efektif, serta bisa bekerja sama dengan baik.
Isolation and Identification of Entomopathogenic Fungi from the Soils of Northwest Iran and their Biological Control Efficacy on the Flour Moth (Ephestia kuehniella)
Authors:   Department of Plant Protection, Tabriz Branch, Islamic Azad University, Tabriz, Iran, Moghasem Mohadeseh , Jamshidi Manizheh , Khakvar Reza ,   Department of Plant Protection, Faculty of Agriculture, University of Tabriz, Tabriz, Iran, Nematollahi Sevil
Published: October 2024

Entomopathogenic fungi have the potential to serve as alternatives to or supplements for chemical pesticides in insect biocontrol, with many of these fungi being utilized in commercial and integrated pest control practices globally. This study aimed to isolate and evaluate the efficacy of various entomopathogenic fungi for the biocontrol of the flour moth, Ephestia kuehniella (Lep: Pyralidae). Multiple isolates of entomopathogenic fungi were acquired from soils across different districts of Azerbaijan province in northwest Iran, and their virulence against E. kuehniella larvae was assessed. Seventeen isolates representing diverse entomopathogenic fungi were isolated and purified using the soil trap method from 20 distinct soil samples. Their pathogenicity against E. kuehniella was evaluated in three replicates through the immersion technique at concentrations of 104, 105, 106, 107, and 108 conidia/mL. Identification of selected fungal isolates was based on morphological features, mycological parameters, and sequencing of the internal transcribed spacer (ITS) region. The study identified seven fungal species, namely Lecanicillium lecanii, Beauveria bassiana, Metarhizium anisopliae, Purpureocillium lilacinum, Aspergillus oryzae, Penicillium citrinum, and Aspergillus lavus, among the 17 isolates collected. Bioassay assessments revealed the susceptibility of 4th-instar larvae of E. kuehniella to the selected isolates, with the larval mortality rate increasing with higher conidial concentrations. A. lavus, A. oryzae, P. citrinum, and P. lilacinum exhibited maximum virulence, causing nearly 90% lethality, while Metarhizium anisopliae demonstrated the lowest level of virulence, resulting in approximately 30% lethality in E. kuehniella. The virulence pattern of isolates across different concentrations was notably distinct. The findings of this research demonstrate that entomopathogenic fungi isolated in this investigation could be effectively incorporated into future pest management programs.