bluuebunny/crossref_metadata_2025 huggingface dataset:
LA INTENCIÓN EMPRENDEDORA EN ESTUDIANTES DEL CANTÓN SANTA ISABEL – ECUADOR
Authors: Cabrera-Pando Verónica Mireya , Ramón Poma Glenda Maricela , Cordero Guzmán Diego Marcelo
Published: November 2024

El emprendimiento en la actualidad es una operación económica que aporta al desarrollo de un país. Por ello, es importante conocer la intención emprendedora que tienen los estudiantes de bachillerato. Por lo que, se realizó una investigación en elcantón Santa Isabel, Azuay, Ecuador. El estudio se trabajó por medio de la metodología cuantitativa, descriptiva, correlacional
y transversal. Se utilizó un cuestionario de encuesta de 21 preguntas con la finalidad de recabar datos tomando como muestra
a 281 estudiantes de bachillerato. Esta encuesta se sometió a un análisis el cual dio un resultado del Alfa de Cronbach de 0,915 de fiabilidad. Los resultados obtenidos luego de analizar los datos mostraron que el comportamiento hacia el emprendimiento es importante por cuanto influye en la disposición emprendedora de los estudiantes. En cambio, la motivación hacia el
emprendimiento no tuvo un efecto significativo. Estos resultados sugieren que las instituciones educativas deben promover una actitud positiva hacia el emprendimiento en los estudiantes. Esto puede ayudar a fomentar el espíritu empresarial y contribuir al desarrollo socioeconómico del país.
Estimación del ciclo económico de Ecuador. Período 2000-2021
Authors: Arévalo Delgado David Renato
Published: November 2024

En el presente estudio, se analiza el comportamiento del ciclo económico del Ecuador con respecto a los componentes de la actividad económica, los ingresos petroleros y las remesas enviadas desde el exterior para el período 2000-2021. Para su realización, se utilizó el filtro Baxter-King y se contrastaron con los resultados obtenidos mediante el filtro Hodrick- Prescott. Entre los principales resultados se evidencia que, el consumo, gasto público, inversión, exportaciones, importaciones
e ingresos petroleros presentan un comportamiento pro cíclico mientras que, las remesas presentan un comportamiento contrario. Finalmente, en el análisis de temporalidad, los resultados difieren en los filtros, sin embargo, el filtro Baxter-King se adhiere de mejor manera a la teoría económica.
LA INTELIGENCIA DE NEGOCIOS COMO APOYO A LA TOMA DE DECISIONES EN EL ÁREA DE COMERCIALIZACIÓN DE LA EMPRESA AZUAYNET
Authors: Arévalo Valarezo Marisela Elizabeth , Neira Picón Paola Noemí
Published: November 2024

La globalización de los mercados y la incorporación de las Tecnologías de la Información y la Comunicación, requiere de las organizaciones una serie de estrategias que refuercen sus operaciones en respuesta al entorno complejo y competitivo en el que ejercen. En este contexto los sistemas de inteligencia de negocios (BI) desempeñan un papel fundamental, puesto que comprenden aplicaciones y herramientas que facilitan la carga, análisis, extracción y reporte de información valiosa para orientar la correcta toma de decisiones, que en el caso de la empresa Azuaynet es limitada, imprecisa y de bajo alcance en su proceso de comercialización, por lo que el objetivo de este artículo es diseñar una arquitectura tecnológica de inteligencia de negocios que faculte la adecuada toma de decisiones. Los resultados reflejan información relevante para que los directivos puedan gestionar con eficacia y eficiencia la operación comercial. La investigación proporciona una herramienta que garantiza la obtención de un punto de vista global de la actividad comercial para la mejora de su competitividad.
IMPACTO DE LA INVERSIÓN EXTRANJERA DIRECTA SOBRE EL CRECIMIENTO ECONÓMICO DEL ECUADOR. PERÍODO 2000-2019
Authors: Vera Saquicela José Antonio , Vásquez Corral David Bernardo
Published: November 2024

El siguiente estudio tiene la finalidad de analizar el impacto de la Inversión Extranjera Directa sobre el crecimiento económico del Ecuador en el periodo 2000-2019. En el desarrollo del trabajo se utilizan datos de periodicidad trimestral obtenidos en el Banco Central de Ecuador a excepción del Riesgo País que ha sido recopilado del sitio web Ámbito. Utilizando un modelo de Vectores Autorregresivos (VAR), se encuentra que, la Inversión Extranjera Directa no tiene efectos significativos sobre la actividad económica. Finalmente, se puede apreciar que, shocks en la Apertura Comercial, tienden a reducir el riesgo país y a dinamizar la economía
Tasas de interés en las colocaciones y captaciones del sector financiero popular y solidario de Azuay, Cañar y Morona Santiago de Ecuador, 2010-2021
Authors: Jimbo Jonathan , Rosales Namicela Mónica
Published: November 2024

El presente trabajo tiene como objetivo analizar la influencia de la variacion de las tasas de interes activas y pasivas y la oferta monetaria en las colocaciones y captaciones respectivamente del sector financiero popular y solidario, en el periodo desde el 2010 hasta el 2021 en las provincias pertenecientes a la zona 6 que son Azuay, Canar y Morona Santiago de la republica de Ecuador, por lo que se inicio con la revision bibliografica de las variables involucradas y para cuantificar estas relaciones se uso el modelo de rezagos distribuidos autorregresivos, que busca analizar las relaciones a largo plazo y a corto plazo entre variables. Donde se evidencio que la tasa de interes activa, la masa monetaria y sus rezagos explican en un 57% a la variable colocaciones, lo que indica que tienen una relacion directa pero no significativa, lo que indica que a medida que la oferta monetaria aumenta las colocaciones aumentan en 2.58 %. En las captaciones se evidencio que su coeficiente de determinacion es (0.99) esto traduce que el 99% de las veces, las variables independientes tasa de interes activa y oferta monetaria con sus rezagos explican el comportamiento de la variable dependiente. De esta manera, se cumple con lo que dice la teoria, que cuando un pais tiene moneda propia las tasas de interes presentan grandes variaciones y en el caso del Ecuador no sucede este hecho, por el uso de moneda extranjera que es el dolar, que ademas es de hegemonia mundial. Finalmente se recomienda enfocar el analisis del sector con otras variables cualitativas y cuantitativas.
Competencias Gerenciales del Administrador de Empresas. Tendencias para la industria 4.0 y los ODS. Una revisión Bibliométrica
Authors: García Ocampo Ximena , Echeverri Rubio Alejandro
Published: November 2024

Con el propósito de identificar las tendencias de investigación en las competencias gerenciales del Administrador de Empresas en la industria 4.0 y su relación con los Objetivos de Desarrollo Sostenible- ODS se hace un abordaje del tema desde el análisis bibliométrico, reconociendo los aspectos relevantes relacionados con esta temática, es así, como se identifican las áreas del conocimiento, los tipos de documentos publicados y su relación con los países y los autores más representativos que han tocado dicho tema; con todo lo anterior se reconocen las tendencias de investigación en este campo de acción. El objetivo de esta investigación es describir el estado de la producción científica relacionada con las competencias gerenciales enmarcadas en la industria 4.0 y su relación con los Objetivos de Desarrollo Sostenible -ODS a partir de la caracterización de los registros bibliográficos de artículos científicos relativos a la temática, indexados en la base de datos Web of Science y publicados en el período 2014-2023. Y así reconocer por medio del análisis bibliométrico las tendencias de investigación mediante el uso de redes de palabras claves y de coocurrencia de palabras. Se concluyó que hay una tendencia al incremento de las publicaciones lideradas por los países desarrollados, y un crecimiento por parte de los países de Latinoamérica.
Análisis Económico del Impacto de la eliminación de subsidios en Ecuador caso: Gasolina, Diésel y GLP
Authors: Sisalima Shiña Santiago
Published: November 2024

En esta investigación, se lleva a cabo una evaluación del impacto económico que surgiría de la eliminación de los subsidios a los combustibles fòsiles (diésel, gasolina y GLP). Con el propósito de evaluar las fluctuaciones en los precios de los factores de producción como consecuencia de la eliminación de estos subsidios, para ello se emplea un modelo econométrico ARIMA de series temporales para realizar proyecciones del Producto Interno Bruto (PIB), una Matriz Insumo Producto (MIP) de Ecuador con información del año 2020, complementando con la ecuación de producción de Leontief, con el fin de fijar la demanda final del Ecuador hasta el año 2027. Una vez establecido lo expuesto anteriormente, se procede a eliminar los subsidios a los combustibles lo cual genera una inflación en los precios de los componentes de producción afectando conjuntamente al consumo intermedio, demanda final y consumo total, en base a estas fluctuaciones se determina los cambios en los índices macroeconómicos y sectoriales del país, estableciendo en el marco de la investigación, una vinculación entre la Matriz Insumo-Producto (MIP) y el modelo econométrico ARIMA. MIP se incorpora de manera integral en el macro modelo, permitiendo resolver uno a partir del otro y viceversa.
Analysis of Tetrachiral Sandwich Structures at High-Velocity Impact: Influence of the Applied Material and Projectile Core Geometry
Authors: Maulana Sultan , Prabowo Aditya Rio , Wibowo Wibowo , Do Quang Thang , Muttaqie Teguh , Muhayat Nurul , Fitri Siti Nurlita
Published: November 2024

This research involved ballistic impact analysis on a tetrachiral sandwich structure in which the shapes of the circular nodes in the tetrachiral core are modified into polygonal shapes, namely a square, hexagon, and octagon. The objectives of this study were to observe the effect of a modified sandwich tetrachiral structure core, investigate the effect of the projectile geometry, and calculate the material performance of the structure. This research was conducted using numerical analysis utilizing the finite element method. The simulation methodology was validated through a benchmarking study, the results of which showed an error below 6%. The findings show that the material with the best performance was Armox 500T, at 5033 J. The most difficult projectile to withstand was conical, followed by ogive, hemispherical, and blunt. The results of the core modification on the tetrachiral sandwich structure show that the octagonal core had better energy absorption, by 2.8%, compared to the circular core. Modifying the node geometry in the tetrachiral core and then analyzing it with stress and strain contours are the novel aspects of this research. Doi: 10.28991/CEJ-2024-010-10-017 Full Text: PDF
Yeni Bulgular Işığında İzmir Kestanepazarı Camii
Authors: Yurdagül Melike , Çakmak Şakir
Published: November 2024

1426 yılında kesin olarak Osmanlı topraklarına katılan İzmir kenti 1480 yılında Fatih Sultan Mehmet’in Liman/Aşağı Kale’yi ihya ettirmesi ile daha korunaklı bir çehre kazanmıştır. 17. yüzyıldan itibaren coğrafi konumu ve dönemin siyasi politikaları gereği önemli bir liman ticareti merkezi haline gelen kentte Liman Kale’nin gerisinde kalan Kemeraltı Çarşısı’nın mimari dokusu bu doğrultuda gelişmiştir. Gelişen ticari faaliyetlere bağlı olarak inşa edilen dükkân, depo ve hanların çevresine konumlandırılan İslami ibadet yapıları da çarşı bölgesinin simgeleri haline gelmiştir. Makalemizin özünü oluşturan Kestanepazarı Camii tarihi çarşı bölgesinde, doldurulan eski iç liman yayı üzerinde yer almaktadır. Bulunduğu ticari dokuya paralel olarak dükkân ve depolardan oluşan bir zemin kat üzerinde yükselen fevkani kuruluşlu yapı, geçirdiği farklı inşa evreleri ile günümüze ulaşmıştır. Önceleri burada yer alan Kızıl İbrahim Mescidi kapasite bakımından yetersiz geldiği gerekçesi ile 1730 yılında Eminzâde Hacı Ahmet Ağa tarafından genişletmek suretiyle yenilenmiş, ancak bu yapı 1868 depreminde zarar gördüğü için Mısırlı Hacı Hüseyin Nuri Efendi tarafından aynı yıl onarılarak plan şeması itibariyle günümüzdeki görünümüne kavuşmuştur. Yapıya ilişkin kaynaklarda Eminzâde Hacı Ahmet Ağa tarafından inşa ettirilen yapının görünümüne ilişkin bir bilgi mevcut değildir. Ancak dijital arşivlerden elde edilen fotoğraflar yapının 1730 yılında Eminzâde Hacı Ahmet Ağa döneminde kazanmış olduğu mimari kuruluşu yansıtması bakımından önem arz etmektedir. Söz konusu fotoğraflar üzerinden Kestanepazarı Camii’nin 1868 yılı öncesindeki görünümü ilk kez yayınımızda irdelenecektir.
Development of a Mobile Pocket Book with a Problem-Based Learning Model to Improve Students Physics Literacy
Authors: Magdalena Magdalena , Harjono Ahmad , Busyairi Ahmad , Ayub Syahrial
Published: November 2024

Physics learning, especially on heat, often faces various obstacles, such as low student literacy and limited interactive learning media. Mobile pocketbooks come as one of the solutions to overcome these problems. This application-based digital learning media is designed to provide easy access to students ' learning materials through mobile devices. The mobile pocketbook is an application-based digital learning media designed to facilitate students' flexible access to learning materials through mobile devices. Using the Problem-Based Learning (PBL) model in the mobile pocketbook supports Active Learning, where students solve real problems to improve concept understanding and science literacy. This research aims to develop and test the validity and practicality of the product in the form of a mobile pocketbook as a medium to support physics learning, especially on heat material. The research method used was Research and Development (R&D) with the 4D development model (Define, Design, Develop, Disseminate). However, due to time and cost constraints, this research did not reach the dissemination stage. Product validity was evaluated through assessments from experts and practitioners. The results of the expert assessment showed a validity level of 92.50%, while the practitioner gave a validity value of 96.25%, which indicated that the product was very valid. In addition, the product practicality test was evaluated through a questionnaire given to students and teachers. The questionnaire’s results show that this media is very practical, with a practicality value from the students' response of 90.76% and the teacher reaching 96.47%. Thus, the mobile pocketbook was designed using a problem-based learning model to improve students' physics science literacy. The results showed that this media is valid and practical for enhancing students' understanding of physics material, especially the concept of heat, as evidenced by the average practicality value of 93.61%. Therefore, this mobile pocketbook is expected to be one of the learning media innovations that can improve the quality of physics learning in schools.
APRECIAÇÃO DA FOTOGRAFIA NA EDUCAÇÃO INFANTIL
Authors: FEITOSA MARIA CLEIDE VIEIRA DA SILVA , Santos Maria da Glória Ramos dos , MOURA RAQUEL COSTA DOS REIS
Published: November 2024

Para esse trabalho foi realizado pesquisas bibliográficas de variados autores na área de Educação e experiências vivenciadas nas salas do maternal I C, Pré I D e Pré II F, da EMEI JEFERSON G. MIRA, de acordo com o projeto desenvolvido na Sala de Formação Alfabetiza MT, tendo como base o Conjunto 14 – FOTOGRAFIA (Pág.225 a 240). A proposta é enfatizar a oportunidade interessante para que as crianças apreciem os trabalhos de fotógrafos e aprendam a tirar as próprias fotos, experimentando diversas formas de capturar detalhes de objetos e de materiais sobre diferentes perspectivas. No decorrer destas experiencias significativas foram acompanhadas um pouco das trajetórias de Fotógrafos renomados como David Reeks e Sebastião Salgado, proporcionando as crianças o despertar da imaginação, a curiosidade, a criatividade, o conhecimento de mundo e diferentes culturas, vivenciando experiências significativas e prazerosas por meio da observação. Após a apreciação das obras dos fotógrafos foi instigado quais meios de fotografar as crianças conheciam e após a roda de conversa foi apresentado imagens de câmera fotográfica antigas através da TV interativa, posteriormente entregamos uma câmera fotográfica para as crianças e as convidamos para passear pelo pátio da escola e fotografassem o que elas mais gostassem, foi um momento mágico de novas descobertas e novos olhares, incentivando a curiosidade e criatividade dos pequenos mesmo que ainda não saibam ler, porém adquirem conhecimentos e se divertem ao mesmo tempo. Também foi solicitado que as crianças fotografassem algo que gostassem e enviassem para serem apreciadas pela turma na sala de referência. No momento de apreciação de suas obras cada criança fez o reconhecimento das suas fotografias que foram realizadas no espaço escolar, na sua sala e fotografias do seu cotidiano com suas famílias e seus animais de estimação. Na sala de aula é importante o professor promover experiências nas quais as crianças possam falar e ouvir, potencializando suas descobertas, pois é na participação em conversas, nas narrativas elaboradas individualmente ou em grupo e nas implicações com as múltiplas linguagens que a criança se constitui ativamente como sujeito singular e pertencente a um grupo social.
Various Theories of Fast and Ultrafast Magnetization Dynamics
Authors: Manfred Fähnle
Published: November 2024

The background of my paper is that magnetization dynamics is a very important subject of basic and technological research. The purpose of the paper is to review various theories of magnetization dynamics. There are many important technological applications of magnetization dynamics.
Suitability of axial-flux matrix-rotor induction motors for low-speed high-torque applications: a robust design approach.
Authors:   , Madariaga Cifuentes Carlos Felipe Ignacio
Published: November 2024

Low-speed high-torque electrical machines have been dominated by permanent magnet synchronous machines, given their high torque density, efficiency and power factor. Nevertheless, in direct-drive low-speed applications, a solution consisting of a conventional induction machine and a mechanical converter is used considering the self-starting capability of the IM and acceptable efficiency of the system. The solution for direct-drive LSHT applications is to adopt machines with inherently low speed, self-starting capacity, and high performance, which has not been possible to date from conventional induction machines and synchronous reluctance machines. In this regard, this thesis addressed the sizing, analysis, and optimization of axial flux induction motors with a novel matrix structure rotor to meet the requirements of LSHT applications. Furthermore, in order to identify the competitivity of these machines and their application niche, opening a path to further research on this promising topology, considering both deterministic and robust design features. Firstly, an analytical pre-sizing methodology focusing on the main and particular design parameters of an AF-MRIM is provided, considering guidelines for a suitable selection of the matrix rotor structure. A semi-analytical tool based on finite element simulations was specifically devised to quickly assess the performance of AF-MRIM, simplifying the matrix rotor structure, and enabling the time-efficiency design and multi-objective optimization of an AF-MRIM, unfeasible to perform with conventional techniques so far. Secondly, several finite-element tools and solutions to assess the effect of unavoidable, manufacturing and assembly tolerances on the performance of asynchronous and synchronous machines are presented, meant to serve as input for a detailed comparative analysis between different machine designs from deterministic and robust design approaches. Finally, a detailed comparison of optimized AF-MRIM with other non-conventional and conventional topologies is provided, considering raw performance and robust design capability. Two objective speeds (250 and 500 rpm) are evaluated by means of specific design optimization and robustness assessment of the different topologies. It was demonstrated that an optimized AF-MRIM has superior performance among rare-earth free topologies but does not reach the performance and torque density of an optimized PMSM. Nonetheless, the MRIM has the highest robustness ratings of all the four selected topologies. At last, it was found that the proposed matrix-rotor IM is actually suitable for LSHT applications, with significant superiority at 250 rpm, direct-drive operation; and slight advantages at 500 rpm when compared to prominent rare-earth free topologies.
Revealing Immersive Guest Experiences (IGX) in the Hotel Industry Using Clustering Analysis
Authors: Yörük Tayfun , Akar Nuray , Karsavuran Zeynep , Almaz Fulya
Published: November 2024

The purpose of this study is to analyze existing research on the use of immersive technologies in the hotel industry and build academic and practical knowledge to explore current areas of immersive technology research and development that are critical for the effective digitalization of the hotel industry. Clustering analysis was applied to the publications analyzed by unsupervised machine learning method using the K-Means algorithm. To verify these concepts and answer the research questions, the clustered publications were subjected to in-depth content analysis within the framework of the research questions. The findings provide comprehensive information on the scope of Immersive Guest Experiences (Hereinafter referred to as IGX) for hotel industry and categorize the antecedents, dimensions, and consequences of IGX in hotels to better understand the reasons for the use of immersive technology in the hotel industry. The results provide guidance for practitioners in the design of IGX in hotels.
PRECORDIAL THUMP AS A LIFE-SAVING RESUSCITATION MEASURE IN OBESE PATIENTS DURING OUT-OF-HOSPITAL CARDIAC ARREST
Authors: Andjelic Sladjana , Mitrasinovic Milica , Mitrovic Ivana
Published: November 2024

Introduction: The precordial thump (PT) was until recently recognized as a life-saving measure for confirmed and monitored shockable rhythm cardiac arrest (CA) cases when a defibrillator is not immediately vailable, but cardiopulmonary resuscitation guidelines no longer mention it.
Objectives: We present the PT as a life-saving measure during CA in obese patient.
Case report: The emergency medical team intervened on a 69-year-old man, with, complaining of chest pain lasting >1h. He was dyspneic, pale and clammy skin. RR 18/min, SatO2 89%, HR 76 bpm, BP of 80/50 mmHg. ECG: anterior ST elevation myocardial infarction with right bundle branch block. He was allergic to aspirin. He was treated with 180mg of oral ticagrelor, a 500ml saline solution IV and 4 l/min O2 by mask and then went into CA. Before the defibrillator became available, patient was treated with three PTs, an oropharyngeal airway placement, bag valve mask ventilation with 100% oxygen and the initiation of chest compressions. When the biphasic defibrillator arrived, the monitor showed coarse ventricular fibrillation. One DC shock with 200J of energy was delivered. After the shock, the patient regained consciousness, a pulse and spontaneous breathing. The ECG monitor showed a sinus rhythm of 143 bpm, BP 80/50 mmHg, and SatO2 89%.
Conclusion: Although CPR guidelines no longer mention the PT, the question remains whether it could be an initial life-saving procedure during CA in obese patients.
Prevalencia de la episiotomía y factores asociados en una institución de alta complejidad en Cali, Colombia, 2022
Authors: Suarez Camargo Monica Nathalia , Cano Bautista Luisa Fernanda , Moreno Benavides Luisa Fernanda , Cubides Munévar Ángela Mayerly , Hernández Carrillo Mauricio
Published: November 2024

Introducción: la episiotomía es un procedimiento obstétrico frecuente, aunque no rutinario, durante la atención de parto, que con el paso de los años va en incremento.
Objetivo: determinar la prevalencia de la episiotomía y factores asociados en una institución de alta complejidad. Metodología: estudio transversal con componente analítico, se incluyeron gestantes con atención de parto durante el primer semestre del año 2022 en una clínica de alta complejidad en Cali, Colombia. Se realizó un muestreo aleatorio con n = 343 partos y un error de 4.1%. Se estimaron frecuencias relativas con un IC 95% y medidas de tendencia central y de dispersión según la distribución de la variable. Para evaluar la asociación y ajustar por factores de con-fusión se realizó una regresión logística múltiple. Resultados: la prevalencia de la episiotomía fue de 37.4% (IC 95%: 32.4% - 42.6%), en multíparas, 13.3% (IC 95%: 8.5% - 19.7%), y en nulíparas del 54.5% (IC 95%: 47.6% - 61.3%). Los factores de riesgo fueron: nuliparidad OR 8.56 IC 95% (4.6 - 15.9), mientras que se identificaron factores protectores, como bajo peso al nacer OR 0.21 IC 95% (0.05 - 0.82), desga-rro grado I OR 0.08 IC 95% (0.03 – 0.22) y desgarro grado II OR 0.17 IC 95% (0.08– 0.034).
Conclusión: la tasa de la episiotomía fue de 37.4%, la cual se encuentra por fuera de los parámetros establecidos por la Organización Mundial de la Salud, por lo que se plantea la necesidad de realizar intervenciones educativas en los pro-fesionales de la salud para reducir estas cifras. Palabras clave: episiotomía; parto; desgarro perineal
1337-1338 (1921-1922) Tarihli Sinop Livası Meclis-i Umumisi Görüşmeleri Çerçevesinde Bölgede İdari, Sosyo-Ekonomik ve Kültürel Faaliyetler
Authors: Alpaslan Erhan
Published: November 2024

Türk idare tarihinde, Tanzimat Fermanı’nın hemen sonrasında uygulanan muhassıllık meclisleriyle başlatılan yerel yönetimlerin doğuşu ve gelişim sürecinde, il özel idaresi açısından, yeni bir adımın atılmasıydı. Bu adım bu dönemde yürürlüğe giren, 1864 Vilayet Nizamnamesiyle atıldı. Bu nizamname, il özel idarelerinin doğuşunun ve il yönetiminde ikili yapıya geçişin miladı olarak kabul edilmektedir. 1864 Vilayet Nizamnamesi ile İdare Meclisleri dışında vilayete özgü bir meclis olan “Meclis-i Umumi–i Vilâyet” adıyla bir meclis daha kuruluyordu. Sadece yerel temsilcilerden oluşan bu meclis, halkın istek ve sorunlarını vilayetin yöneticilerine ileten ve danışma görevini yerine getiren bir fonksiyona sahipti. Vilâyet Umumi Meclisi, seçimle işbaşına gelen kalabalık bir üye yapısına sahipti ve yılda bir defa vilayet merkezinde toplanırdı. Görevleri vilayet nizamnamesinde vilayetin özel işleri olarak belirlenmişti. Genel meclislerin oluşturulmasından itibaren bu meclislerde dönemsel olarak meclis üyelerinde, meclis sorumluluklarında ve yetki alanlarında düzenlemeler ve yeniliklerin olduğunu görmekteyiz. Bu meclislerin günümüzde il özel idareleri olarak görev yaptığı anlaşılmaktadır. Bu çalışmada Sinop Sancağı Meclisi Umum’sinin R. 1337-1338 (M.1921-1922) yılı görüşmeleri ve alınan kararlar üzerine bir değerlendirilme yapılmıştır.
Kütahya Sancağı'nda 1912 Meclis-i Mebusan Seçimleri
Authors: Bilgin Taner , Erden Kürşat Nusret
Published: November 2024

23 Temmuz 1908’de Meşrutiyetin ilan edilmesinin ardından Osmanlı Devleti, seçim sürecine girdi. II. Meşrutiyet’in ilk devre seçimleri olan 1908 seçimlerinde İttihat ve Terakki Cemiyeti, karşısında henüz ülke genelinde örgütlenmiş bir siyasi fırka söz konusu değildi. Bu yüzden İttihat ve Terakki Cemiyeti bu seçimlere kendi açısından rahat bir ortamda girdi. Ancak ilerleyen süreçte ülke içinde ve dışında sorunların artmasıyla birlikte İttihat ve Terakki Cemiyetine karşı yavaş yavaş örgütlenen muhalefet cephesi oluşmaya başladı. 1911 yılına gelindiğinde İttihatçı saflarında çözülme hızlandı. Nitekim Miralay Sadık ve Abdülaziz Mecdi Bey’in önderliğinde “Hizbi Cedid” adlı grup oluşturuldu. Bu grup 21 Kasım 1911’de Hürriyet ve İtilaf Fırkası’nı kurarak İttihat ve Terakki Cemiyetine karşı siyaset sahnesine çıktı. Meşrutiyet döneminin ikinci dönem seçim süreci ise 18 Ocak 1912’de Osmanlı Mebusan Meclisi’nin feshedilmesiyle başladı. Meclisin kapatılmasının ardından her iki fırka da çatışmalı bir seçim kampanyası yürüttü. 1912 Mart-Nisan ayları arasında yapılan seçimler, Türk siyasi tarihinde ilk erken seçim olmanın yanında “Dayaklı ve sopalı seçim” olarak da anıldı. Ancak bu tabir, Fevzi Demir'in belirttiği gibi daha çok İstanbul ve Makedonya'da yaşanan olaylar dolayısıyla verilmişti. Bu makalede Anadolu'da 1912 seçimlerinin nasıl gerçekleştiği sorusuna Kütahya Sancağı özelinde cevap aranmaya çalışılmıştır. Yapılan çalışmada arşiv ve yerel kaynakların yanı sıra İttihat ve Terakki Cemiyeti ile Hürriyet ve İtilaf Fırkası’nın sözcülüğünü üstlenen Hakikat, Tanin, İkdam, İktiham, Teminat ve Meslek gibi dönemin yerel ve ulusal gazetelerinden yararlanılmıştır. Bu sayede siyasî fırkaların 1912 seçimlerinde Kütahya Sancağı’nda siyasî faaliyetleri ve seçim sürecinin işleyişi tespit edilmeye çalışılmıştır. Ayrıca yeni kurulan Hürriyet ve İtilaf Fırkasının Kütahya merkezi ile ona bağlı Eskişehir ve Uşak ilçelerindeki teşkilatlanışı, bu bölgelerde hangi kesimler tarafından desteklendiği ve teşkilatlanmanın seçime etkileri incelenmeye çalışılmıştır.
The First Years of the Kaunas Dominicans (1641–1655)
Authors: Kamuntavičienė Vaida
Published: November 2024

The aim of this article is to analyse the process of the establishment of the Kaunas Dominicans between 1631 and 1641, and to discuss the first years of the Kaunas friary’s existence up to the occupation of Kaunas in 1655, and the subsequent wars and cataclysms. It was in this period that the foundations of the Kaunas friary’s existence were laid and the main devotional practices were formed. Even though the historian Sławomir Brzozecki has revealed the main moments in the existence of the Lithuanian province of the Dominicans, and Jurgis Oksas has conducted research into the development of the plot of land administered by the Kaunas Dominicans and the construction of the church and friary, the structure, activities and importance of the Kaunas Dominican community have yet to be discussed. In this article, the establishment of the Dominicans in Kaunas is shown in the context of the formation of the Lithuanian Dominican Province, the role of the provincial Petroniusz Kamieński in creating the Kaunas friary is shown, the dating of the founding of the Kaunas friary is corrected, the sponsor-patrons and other people of goodwill, and the institution’s material situation, are discussed, the first known Dominican friars and features of their daily life are determined, and their devotional practices, which reflect general trends in the Dominican Order, are described, pointing out local features. This research is important as a case study for revealing the activities of the Dominicans in the Early Modern Period.
Survive and Thrive in the Time of Changes: A Bibliometric Review of Teacher Resilience, 1998–2023
Authors: Li Xinlin , Chen Junjun
Published: November 2024

Teacher resilience literature has expanded rapidly with a large number of publications and an evolving knowledge base. To capture a synthetic account systematically and effectively, this review provides a bibliometric approach to quantitatively examine the metadata of 692 relevant publications during the 26 years from 1998 to 2023.

The finding traces the field’s progression from an initial concern for at-risk children to early conceptual discussions of resilience and, ultimately, more in-depth theoretical, empirical, and experimental investigations of teacher resilience, particularly within specific contexts like language teaching. However, the future trajectory of this domain remains an open question.

The bibliometric review also enabled the researchers to anchor future research directions and contemplate the key challenges, such as the need for more international collaborations, concerted efforts to study teacher resilience across varied contexts, and the need to carefully balance productivity and influence when conducting new studies. Overall, this review aims to spark thoughtful discussions among researchers, practitioners, and policymakers regarding teacher resilience, in order to establish a more sustainable and global knowledge base.
Extracting Quercetin from Different Plant Sources, Purifying It Using Different Extraction Methods (Chemical, Physical, and Enzymatic), and Measuring Its Antioxidant Activity
Authors: Baqer Safa Hussein , Al-Younis Zena Kadhim , Al-Shawi Sarmad Ghazi
Published: November 2024

Background: Flavonoids are among the most important compounds found in plants, since laboratory studies have shown them to be a daily requirement in human diets due to their various health benefits. Therefore, this study focused on extracting, purifying, and measuring the antioxidant activity of the flavonoid quercetin, which is widely found in plants and possesses a variety of biological activities, from different plant sources. Methods: The extraction of quercetin was performed using several methods (chemical, physical, and enzymatic) and several extraction solutions (water, ethanol, and chloroform) from several plants (spinach, dill, Onion Skin, Pistacia eurycarpa, sumac, digalkhasab chemri, and leelwi chemri). The alcoholic extract extracted by chemical method was purified and the content of total flavonoids based on quercetin in all plant extracts was determined using adsorption chromatography on a silica gel column (100–200 mesh), followed by thin layer chromatography (TLC). TLC and high performance liquid chromatography (HPLC) were used to assess the purity of quercetin. The ability of quercetin to capture free radicals using 2,2-diphenyl-1-picrylhydrazyl (DPPH) was compared to that of butylated hydroxytoluene (BHT). Statistical analyses were performed using completely randomized designs (CRD) for factorial experiments, and the least significant difference (LSD) test was used to calculate the significant differences between the averages of the coefficients at the 0.05 probability level. Results: The alcoholic Pistacia extract extracted by chemical method yielded the highest concentration of quercetin (84.037 mg/g). Furthermore, it was found that quercetin purified from Pistacia possessed strong antioxidant activity, and its antioxidant activity increased with increased concentration. Conclusions: Pistacia eurycarpa showed the highest quercetin content among the assessed plants. Moreover, solvents played a major role in extracting plant components due to the high polarity of flavonoids. Quercetin purified using a silica gel column demonstrated antioxidant activity.
The PLCG2 Inhibits Tumor Progression and Mediates Angiogenesis by VEGF Signaling Pathway in Clear Cell Renal Cell Carcinoma
Authors: Zhao Chuanyi , Miao Daojia , Tan Diaoyi , Shi Jian , Lv Qingyang , Xiong Zhiyong , Zhang Xiaoping
Published: November 2024

Background: Clear cell renal cell carcinoma (ccRCC) represents the most prevalent form of renal cell carcinoma. The management of early-stage ccRCC has a better prognosis, while patients with metastatic ccRCC have a lower five-year survival rate. Angiogenesis serves as the fundamental process underlying tumor metastasis. Therefore, it is crucial to discover new targets for angiogenesis to improve patient survival rates. Methods: The Cancer Genome Atlas database, International Cancer Genome Consortium database, Clinical Proteomic Tumor Analysis Consortium database, and a gene set of the vascular endothelial growth factor (VEGF) signaling pathway were utilized to identify differentially expressed genes. Western blot (WB), quantitative real-time polymerase chain reaction, and immunohistochemistry were employed to validate the downregulation of phospholipase C gamma 2 (PLCG2) in ccRCC tissues and cells. Cell Counting Kit-8 (CCK-8) assays, transwell assays, tube formation assays, and oil-red staining were performed to elucidate the biological functions of PLCG2 in tumor cells. Gene set enrichment analysis was applied to explore the downstream pathway. Subcutaneous tumor models and live small animal fluorescent imaging assay were utilized for in vivo investigation of the roles played by PLCG2. Results: Our study has identified a novel biomarker, PLCG2, for ccRCC. PLCG2 is a central gene in regulating angiogenesis in ccRCC, as validated by bioinformatics analysis. The findings revealed a diminished expression of PLCG2 in both ccRCC tissues and cells. Further experiments in vivo and in vitro have demonstrated the significant roles of PLCG2 in tumor proliferation, invasion, migration, and lipid accumulation. Results of tube formation assays and WB support the role of PLCG2 in regulating VEGFA expression and angiogenesis. Conclusions: Our results show that PLCG2 functions as a potential biomarker and an independent prognostic indicator for ccRCC. PLCG2 may modulate angiogenesis by influencing the expression of VEGFA. Therefore, targeting PLCG2 could potentially lead to drug discovery and improved cancer treatment strategies.
SENP1 Promotes Caspase-11 Inflammasome Activation and Aggravates Inflammatory Response in Murine Acute Lung Injury Induced by Lipopolysaccharide
Authors: Du Mingjun , Wang Wenhan , Zhang Shaoyuan , Gu Jianmin , Zhang Chunbing , Zhang Hai
Published: November 2024

Background: Infection is the leading cause of acute lung injury (ALI). Macrophages, which are pivotal innate immune cells, play a critical role in mediating inflammatory processes. Intracellular lipopolysaccharide (LPS) from invasive Gram-negative bacteria can activate the caspase-11 inflammasome, leading to the induction of pyroptosis in macrophages. This process subsequently triggers the release of inflammatory cytokines and damage-associated molecular patterns from pyroptotic macrophages, thereby exacerbating inflammatory progression in ALI. However, the precise regulatory mechanisms governing caspase-11 activation is still unclear. Sentrin-specific proteases (SENPs) have been identified as notable targets for their anti-inflammatory properties. Nevertheless, the specific role of SENPs in macrophage pyroptosis during the pathogenesis of ALI remains unknown. Methods: We used LPS as an endotoxin to induce ALI. We analyzed the expression and location of sentrin-specific protease 1 (SENP1), pulmonary impairment, macrophage infiltration, caspase-11 inflammasome expression and activation, caspase-11 SUMOylation, and inflammatory cytokine secretion. Results: Upregulated expression of SENP1 in lung tissue and macrophages was observed following LPS stimulation. SENP1 mediates de-SUMOylation and activation of caspase-11 inflammasome in macrophages. Moreover, pharmacological inhibition or genetic deficiency of SENP1 in macrophages significantly improved ALI-related histological damage by reducing the secretion of inflammatory cytokines and suppressing caspase-11-dependent pyroptosis. Conclusions: Collectively, our findings highlight the involvement of SENP1 in caspase-11 activation and inflammatory progression in macrophages, thereby establishing a scientific foundation for the exploration of novel therapeutic strategies aimed at treating ALI.
Predictive Value of Coronary Calcifications for Future Cardiac Events in Asymptomatic Patients with Severe Chronic Kidney Disease
Authors: Greif Martin , Lackermair Korbinian , Wessely Matthias , von Ziegler Franz , Becker Alexander
Published: November 2024

Background: Coronary calcification is a well-established risk factor for cardiovascular events. This retrospective study sought to determine the predictive value of coronary calcification in a specific group of patients with chronic kidney disease. Methods: We included 1094 asymptomatic patients (724 males, 370 females, age 62 ± 9.3 years) referred for cardiological examination. Patents were divided into two groups depending on their renal function. Coronary calcification was determined with a multi-slice computer tomography (CT) scanner. For quantification of coronary calcification the Agatston score was calculated. Over a mean follow up period of 6.2 ± 1.3 years we observed the rate of cardiovascular events (185 events, 61 myocardial infarctions, 103 revascularizations, 21 cardiac deaths). Results: The calcium score was significantly higher in patients with severe kidney disease (glomerular filtration rate (GFR) ≤30 mL/min/1.72 m2) compared with those with normal to moderate reduced renal function (GFR ≥30 mL/min/1.72 m2) (207 ± 190 vs.121 ± 169, p ≤ 0.001). The event rate in patients with severe impaired renal function was significantly higher compared to patients with normal to moderate reduced renal function (20.6% vs. 14.8%, p = 0.0001). The hazard ratio for cardiovascular events increased constantly with the calcium score in both groups. The hazard ratio in patients with severe kidney disease was significantly lower compared to patients in corresponding groups with regular to moderate reduced renal function (7.3 vs. 9.3, p = 0.01). No cardiac events were observed in patients with a calcium score of 0. Conclusions: We could demonstrate that risk prediction with the calcium score is possible in patients with severe chronic kidney disease even if the calcium score overestimates the risk for future cardiovascular events compared to patients with normal to moderate reduced renal function.
Early and Mid-Term Outcomes of Coronary Protection during Transcatheter Aortic Valve Replacement: A Single-Center Retrospective Analysis
Authors: Zhou Jiawei , Li Yuehuan , Shen Jinglun , Wu Kaisheng , Wang Jiangang , Yu Yi , Zhang Haibo
Published: November 2024

Background: Coronary obstruction (CO) is a fatal complication in transcatheter aortic valve replacement (TAVR). However, data on the outcomes and details of coronary protection (CP) use in TAVR are limited. Methods: We retrospectively analyzed the patients who had undergone CP during TAVR at our tertiary cardiac center from March 2017 to January 2024. CP was achieved by an undeployed coronary balloon or stent positioned within the coronary artery, which releases the stent at CO occurrence. Patients' computed tomography (CT) evaluation reports and perioperative and follow-up outcomes were reviewed. Results: A total of 33 out of 493 patients (6.7%) underwent CP during TAVR due to the high risk of CO based on preoperative CT analysis. The mean sinus dimensions measured 30.1 ± 3.6 mm, 29.2 ± 3.4 mm, and 30.4 ± 3.7 mm for the left, right, and non-coronary sinus, respectively. The average left main height was 11.7 mm, and the right coronary height was 14 mm. Self-expanding valves were used in 93.9% of the patients. Coronary balloons were used for CP in 30 patients, whereas undeployed coronary stents were used in three cases. A total of 36 coronary arteries were protected, including 28 left coronary arteries alone, two right coronary arteries alone, and three dual coronary arteries. Eight patients (24.2%) developed CO and underwent stent release. The in-hospital and 30-day all-cause mortality rates were 9.1% and 0%, respectively. The median follow-up time was 10 months, and only one patient died 2 months after discharge due to stroke during the follow-up. Conclusions: Pre-emptive coronary balloons or stents for CP allow for revascularization in the shortest possible time in the event of CO. Early and mid-term outcomes of CP during TAVR in patients with a high risk of CO show that CP is safe and feasible.
Evaluation of Right Heart Structure and Function in Pacemaker-dependent Patients by Two-Dimensional Speckle Tracking Echocardiography: A 1-Year Prospective Cohort Study
Authors: Mei Yingchen , Han Rui , Cheng Liting , Li Haiwei , He Yihua , Liu Wei , Wu Yongquan
Published: November 2024

Background: Left bundle branch area pacing (LBBAP) has evolved into a practical and secure pacing procedure. However, previous studies of LBBAP focused on left heart function and synchronization and lacked assessment of right heart structure and function and interventricular synchrony. The objective of this study was to examine the impacts of LBBAP, right ventricular (RV) septal pacing (RVSP), and RV apical pacing (RVAP) on right heart structure, function and interventricular synchrony. Methods: Between January and July 2021, A total of 90 patients exhibited a normal left ventricular (LV) ejection fraction and received dual chamber pacemaker implantation for bradycardia at Beijing Anzhen Hospital. The patients were assigned to three groups based on the pacing site: LBBAP, RVSP, or RVAP. RV function was evaluated using right ventricular fractional area change (RVFAC), tricuspid annular plane systolic excursion (TAPSE), tissue Doppler–derived tricuspid lateral annular systolic velocity (S'), right ventricular myocardial performance index (RVMPI), global longitudinal strain of the right ventricle (GLSRV), and right ventricular free wall longitudinal strain (RVFWLS). Tricuspid regurgitation (TR) was assessed using vena contracta magnitude (VCM) and the ratio of TR jet area to right atrial area (RAA). Interventricular mechanical synchrony was evaluated using interventricular mechanical delay (IVMD) and left ventricular to right ventricular time-to-peak standard deviation (LV-RV TPSD). Results: Baseline echocardiographic parameters and characteristics were comparable among the three groups. No significant differences were observed in the LBBAP group from baseline to follow-up for QRS duration (p = 0.783), TAPSE (p = 0.122), RVFAC (p = 0.679), RVMPI (p = 0.93), GLSRV (p = 0.511), RVFWLS (p = 0.939), VCM (p = 0.467), and TR jet area/RAA (p = 0.667). In contrast, a significant decline was observed in the RVAP group (all p < 0.05). RVSP resulted in a similar percentage reduction in TAPSE, GLSRV, and RVFWLS (all p > 0.05). However, there were significant differences in RVFAC (p = 0.009), RVMPI (p = 0.037), TRVCM (p = 0.046), and TR jet area/RAA (p = 0.033) in the RVSP group. Moreover, compared to baseline, a 1-year follow-up showed that LBBAP significantly reduced IVMD (from 17.3 ± 26.5 ms to 8.6 ± 7.1 ms, p < 0.05) and LV-RV TPSD [from 16.41 (8.81–42.5) to 12.28 (5.64–23.7), p < 0.05], while RVSP and RVAP worsened IVMD and LV-RV TPSD (all p < 0.05). Conclusions: Compared with RVSP or RVAP, LBBAP can maintain RV function and improve electrical and interventricular synchrony, with limited TR deterioration after a 1-year follow-up. Clinical Trial Registration: No. ChiCTR2100048503, https://www.chictr.org.cn/showproj.html?proj=129290.
Gardening as a responsible leisure activity: The geography of Central European food self-provisioning
Authors: Daněk Petr , Jehlička Petr
Published: November 2024

Recent research on food self-provisioning (FSP) has pointed to its material similarity with the practices of alternative food networks (AFNs) – a subject of enormous scholarly interest in the last two decades. Most of the limited research on FSP has so far focused on comparing gardeners with the non-gardening population in a single country and overlooked geographical differences in FSP practices. The objective of this article is to assess the differences in FSP in two Central European countries (Austria and Czechia) and between urban, suburban and rural areas. More specifically, we have analysed robust survey data on 1,284 households practising gardening with the objective of comparing FSP practices in different geographical settings in terms of time spent in the garden, motivations for growing food, the volume of vegetable production, the extent of mutual help and food sharing and fertiliser and pesticide use. The results reveal similarities rather than differences between geographical categories, despite a significant disparity in living standards between the two countries. Associating FSP with the quality of produce and a leisure activity rather than poverty or obligation, as well as proving its comparable relevance in both rural and urban areas and across international boundaries, contributes to bridging the gap between research on AFNs and FSP. It also demonstrates that food alternatives have significantly greater material significance in terms of volume of production and the number of participants than previously realised.