bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Wet-Dry Cycling on the Phase Behavior and Compartmentalization Properties of Complex Coacervates
Authors: Fares Hadi , Marras Alexander , Ting Jeffrey , Tirrell Matthew , Keating Christine
Published: May 2020

Wet-dry cycling on the early Earth is thought to have facilitated production of molecular building blocks of life, but thus far its impact on self-assembly and compartmentalization of resulting (macro)molecules has been limited. We investigated dehydration/rehydration of complex coacervates, which are membraneless compartments formed by phase separation of polyelectrolyte solutions, and suggested as protocell models. Depending on initial composition of a poly(diallyldimethylammonium)/poly(acrylic acid) system, drying enabled formation or disassembly of coacervate droplets. In compartments surviving tenfold dehydration, partitioning of a fluorescent RNA oligonucleotide decreased, while its local concentration inside the coacervates remained nearly constant, despite increasing tenfold globally. RNA mobility was also enhanced as the system dehydrated. These changes can be understood as resulting from drying induced compositional movements on the phase diagram, with increased ionic strength being particularly important in determining coacervate properties. These results showed that wet-dry cycling can alter the phase behavior and protocell-relevant functions of complex coacervates.
14N1H HMQC Solid-State NMR as a Powerful Tool to Study Amorphous Formulations – an Exemplary Study of Paclitaxel Loaded Polymer Micelles
Authors: Grüne Marvin , Luxenhofer Robert , Iuga Dinu , Brown Steven P. , Pöppler Ann-Christin
Published: May 2020

We present 14N-1H HMQC MAS NMR experiments in the solid state as a promising tool to study amorphous formulations. Poly(2-oxazoline) based polymer micelles loaded with different amounts of the cancer drug paclitaxel serve to highlight the possibilities offered by these experiments: While the very similar 15N chemical shifts hamper a solid-state NMR characterization based on this nucleus, 14N is a very versatile alternative. 14N-1H HMQC experiments yield well-separated signals, which are spread over a large ppm range, provide information on the symmetry of the nitrogen environment and probe 14N-1H through-space proximities.
A Hydrogen Bond Between Linear Tetrapyrrole and Conserved Aspartate Causes the Far-Red Shifted Absorption of Phytochrome Photoreceptors
Authors: Maximowitsch Egle , Domratcheva Tatiana
Published: May 2020

Photoswitching of phytochrome photoreceptors between red-absorbing (Pr) and far-red absorbing (Pfr) states triggers light adaptation of plants, bacteria and other organisms. Using quantum chemistry, we elucidate the color-tuning mechanism of phytochromes and identify the origin of the Pfr-state red-shifted spectrum. Spectral variations are explained by resonance interactions of the protonated linear tetrapyrrole chromophore. In particular, hydrogen bonding of pyrrole ring D with the strictly conserved aspartate shifts the positive charge towards ring D thereby inducing the red spectral shift. Our MD simulations demonstrate that formation of the ring D–aspartate hydrogen bond depends on interactions between the chromophore binding domain (CBD) and phytochrome specific domain (PHY). Our study guides rational engineering of fluorescent phytochromes with a far-red shifted spectrum.
Improving Printability of a Thermoresponsive Hydrogel Biomaterial Ink by Nanoclay Addition
Authors: Hu Chen , Hahn Lukas , Yang Mengshi , Altmann Alexander , Stahlhut Philipp , Groll Jürgen , Luxenhofer Robert
Published: May 2020

As a promising biofabrication technology, extrusion-based bioprinting has gained significant attention in the last decade and major advances have been made in the development of bioinks. However suitable synthetic and stimuli-responsive bioinks are underrepresented in this context. In this work, we described a hybrid system of nanoclay Laponite XLG and thermoresponsive block copolymer poly(2-methyl-2-oxazoline)-b-poly(2-n-propyl-2-oxazine) (PMeOx-b-PnPrOzi) as a novel biomaterial ink, and discussed its critical properties relevant for extrusion-based bioprinting, including viscoelastic properties and printability. The hybrid hydrogel retains the thermogelling properties but is strengthened by the added clay (over 5 kPa of storage modulus, and 240 Pa of yield stress). Importantly, the shear-thinning character is further enhanced, which, in combination with very rapid viscosity recovery (~1 s) and structure recovery (~10 s) is highly beneficial for extrusion-based 3D printing. Accordingly, various 3D patterns could be printed with markedly enhanced resolution and shape fidelity compared to the biomaterial ink without added clay.
Endowing Nanozymes High Biocatalytic Selectivity by Substrates Channeling and Screening
Authors: Zhou Qing , Yang Hong , Chen Xinghua , Xu Yuan , Han Dan , Zhou Sisi , Liu Songqin , Shen Yanfei , Zhang Yuanjian
Published: May 2020

As an alternative to surmount the weakness of natural enzymes, nanozymes have recently attracted extensive attention from early disease diagnosis to tumor therapy. However, due to the lack of enzyme-like molecular recognition units, the poor substrate selectivity of nanozyme-catalyzed reaction significantly restricts their widespread applications. By biomimicking the ingenuity of metabolism process in living, herein we report a multiple-nanozymes system capable of improving the substrate selectivity via cascade reactions in a confined space. As a showcase, the nitrogen-doped carbon nanocages (NCNC) and Prussian blue nanoparticles (PB NPs) were successfully coupled in a microfluidic device to highly selective oxidation and detection of ascorbic acid (AA, an important electron donor and catalyst for alleviation of oxidative stress) against other interferences. It was revealed that the products of the prior nanozymatic reaction were effectively screened as the reactants of the next one, thus stepwise improving the overall selectivity of the all-nanozyme system. This work may open a new door to improve the selectivity of all-nanozyme-system for prospect applications.
Ketoliz defekti tanısıyla izlenen 16 hastanın klinik ve moleküler özelliklerinin incelenmesi: Tek merkez deneyimi
Authors: BULUT Fatma Derya , KOR Deniz , KILAVUZ Sebile , ŞEKER Berna , ÖZCAN Neslihan , INCECİK Faruk , BİŞGİN Atıl , YILDIZDAŞ Dinçer , ÖNENLİ MUNGAN H. Neslihan
Published: May 2020

Amaç: Beta-ketotiolaz (T2) ve suksinil-KoA:3-ketoasit KoA transferaz (SCOT) keton cisimlerinin yıkımında görev alan iki enzimdir. Ketolizde görevli bu iki enzimin eksikliğinde erken çocuklukta açlık veya diğer katabolik süreçlerle tetiklenen ve tekrarlayan ketoasidoz atakları görülür. Bu çalışmada, ketoliz defekti tanısıyla izlenen hastaların klinik ve moleküler özelliklerinin incelenmesi amaçlandı. Yöntem: Çukurova Üniversitesi Çocuk Metabolizma ve Beslenme Bilim Dalı’nda takipli 15 T2 eksikliği ve bir SCOT eksikliği tanılı hasta çalışmaya dahil edildi. Geriye dönük hastaların tıbbi kayıtları incelendi. Bulgular: Hastaların sekizi kız, sekizi erkekti. 13 hastada anne-baba akrabalığı, 11 hastada aile öyküsü vardı. SCOT eksikliği olan hastanın ilk ketoasidoz atağı iki günlükken olmuştu. T2 eksikliği olan hastalarda ise ilk atak yaşı ortalama 8,0±6,7 aydı (4 gün-29 ay). SCOT eksikliği olan hastanın atakları arasında hem negatif hem pozitif aseton değerleri olması ilginç özelliğiydi. T2 eksikliği tanılı hastaların tümünde atak dışında keton hep negatifti. Atak sırasında 10 hastada hipoglisemi, altısında ise hiperglisemi görüldü. Hastaların izlem süresince ortalama atak sayısı 3,8±3,1 idi. Hastalardan tanı ve ayırıcı tanı için açilkarnitin profili ve organik asit analizi çalışıldı. Mutasyon analizi yapılabilen 11 hastadan 10’unda bulunan mutasyonlar literatürde ilk kez bu çalışmayla tanımlandı. Sonuç: Ketoasidoz tablosunda gelen hastalarda organik asidemi ayırıcı tanısında daha nadir görülseler de ketoliz defektlerinin akılda tutulması gereklidir. Organik asidemilerden farklı olarak hastaların çoğunda kan şekeri ve beslenme durumundan bağımsız süreğen ketozisin olması, tipik organik asit ve açilkarnitin profili en önemli tanısal ipuçlarıdır. Bu gruptaki iki hastalığın tedavileri organik asidemiler kadar ciddi ve süreğen protein kısıtlaması ve kofaktör desteği gerektirmediğinden hem hastaların büyümelerini hem de yaşam kalitelerini daha az etkilemektedir.
Qualifying the TIG orbital welding technology of titanium pipes with a perforated bottom
Authors: Górka Jacek , Przybyła Mateusz , Chudzio Andrzej , Ładak Dariusz , Szmul Marcin
Published: May 2020

The article presents the method of qualifying orbital welding technology using the TIG (142) method of the perforated bottom heat exchanger made of steel A516M (Grade 485) explosively clad with titanium B265 (Grade 1) with titanium pipes B338 (Grade 2) with a diameter of 34.93 mm and thickness 0.7 mm. Based on preliminary tests, welding technologies have been developed that meet the acceptance criteria for acceptance requirements. Qualification of the developed technology and welding parameters that were used during welding was carried out in accordance with PN-EN ISO 15614 Specification and qualification of metal welding technology, welding technology testing, Part 8: Welding of tubes with perforated bottom. This standard specifies the requirements for the qualification of automatic arc welding technology, metal pipe joints with perforated bottom by means of technology testing.
DEĞİŞEN JANDARMA TÖREN KIYAFETİNİN PERSONEL İMAJ VE AİDİYET ALGISINA ETKİSİ
Authors: KAPLAN Mehmet
Published: May 2020

İş giysileri çalışanların gereksinimlerine uygunluğunun yanı sıra kurum imajı ve insan kaynaklarından yararlanma gibi kurum dinamiklerini de etkileyebilmektedir. Kurumlar imajlarına göre ve vermek istedikleri mesaja göre üniformalarının model ve rengini seçmektedir. Jandarma Genel Komutanlığında üniforma şeref ve onur timsali olarak görülür ve kurumsal imajının somut halidir. Jandarma Genel Komutanlığı Türk Silahlı Kuvvetlerinden ayrılarak tamamen İçişleri Bakanlığına bağlanması sonrasında 1 numaralı (harici) üniforması da değişmiştir. Bu araştırmada amaç, yeni bir kimlik oluşturma doğrultusunda seçilen siyah renkli 1 numaralı üniformanın jandarma personelinin imaj ve aidiyet algılarına etkisini ortaya çıkarmaktır. İyi seçilmiş bir üniforma çalışanların moralini yükseltmekte, kurum atmosferine katkıda bulunmakta ve kurumun hizmet verdiği bireylerin tatmin düzeyini artırmaktadır. Bu doğrultuda yeni kıyafetin personel imaj ve aidiyet algısına etkisinin ortaya konulmasında elde edilen sonuçların faydalı olacağı beklenmektedir. Bu çalışmada Ankara’da farklı birimlerde görev yapan 20 subay, 36 astsubay ve 23 uzman jandarma çavuş/uzman erbaş statüsünde toplam 79 jandarma personeline yarı yapılandırılmış sorular sorulmuştur. Elde edilen veriler yeni, 1 numaralı kıyafetin imaja ve aidiyete etkileri olmak üzere iki tema altında sınıflandırılmıştır. Görüşmeye katılanların yüzde 62’si yeni üniformanın imaja katkısıyla ilgili, yüzde 43’ü aidiyete katkısı ile ilgili olumlu görüş bildirmiştir. Etkisi olmayacağını bildirenlerin sayısı olumsuz olacağını bildirenlerin sayısından daha fazladır. Üniforma değişimini askerlikten kopma olarak gören subaylar olumsuz düşünceye sahipken uzman jandarma çavuş/uzman erbaşlar ise bunu olumlu görmektedir.
SİLAHLI KUVVETLERİN KURUMSAL DÖNÜŞÜMÜNÜ İNCELEMEK: BÜTÜNCÜL BİR KURAMSAL ÇERÇEVE ÖNERİSİ
Authors: BARBAK Ahmet
Published: May 2020

Bu makalenin amacı, silahlı kuvvetlerin kurumsal dönüşümünü incelemeye yönelik bir kuramsal çerçeve önermektir. 1970’lerden itibaren siyasal, ekonomik ve toplumsal alanlarda ileri sürülen kuramsal yaklaşımlar genellikle post-modern, post-fordist ve/veya neoliberal olarak nitelenmektedir. Devleti ve onun idari vasıtası olan kamu yönetimini yeniden yapılandırmayı amaçlayan bu yaklaşımlar, devletin meşru güç kullanma tekelini temsil eden ve modern bürokratik devlet düşüncesine göre örgütlenmiş olan silahlı kuvvetlerin kurumsal değişimini de hedeflemiştir. Bu süreçte, silahlı kuvvetlerin bir taraftan meşru güç kullanma tekelinin diğer taraftan bürokratik örgütlenme biçiminin dönüşümü üzerinden hem düşünsel olarak hem de uygulamada yeniden inşa edildiği gözlenmektedir. Bu çalışma, ülkelerin silahlı kuvvetlerindeki dönüşümün genel olarak devlet aygıtı ve kamu yönetimine ilişkin değişimden bağımsız ele alınamayacağını savunmaktadır. Bu kapsamda, çalışmada önerilen kuramsal çerçevenin ana gövdesini kamu yönetimi ve onun yakın ilişki içinde olduğu disiplinler oluşturmaktadır. Kuramsal çerçeve ekonomik (Yeni Kurumcu İktisat), siyasi (Demokratikleştirme) ve yönetsel (Yeni Kamu İşletmeciliği) boyutları içermektedir. Çalışma, farklı bir bilimsel disiplin kullanarak veya kuramsal değişimlere göre farklı veya tamamlayıcı kuramsal çerçevelerin oluşturulabileceğini kabul etmektedir.
TERÖRİZM KAYNAKLI TEHDİTLERDE İSTİHBARAT KURUMLARININ TEHDİT DEĞERLENDİRMESİ: GELENEKSEL YAKLAŞIM
Authors: ÖVET Talha
Published: May 2020

İstihbarat kurumlarının ana görevlerinden en önemlisi tehdidin tanımlanması, analiz edilmesi ve değerlendirilmesidir. Singer tarafından tanımlanan tehdit değerlendirmesi modeli istihbarat literatürü ve istihbarat uygulaması içerisinde temel konsepttir. İki parametreli (niyet ve kapasite) bu model, hem devlet temelli hem de terörizm temelli tehditleri değerlendirmek için istihbarat kurumları tarafından kullanılan geleneksel yaklaşımdır. Tehditlerin doğası ve karakteristiğinde anlamlı ve önemli değişiklikler olmasına rağmen, tehditleri değerlendirmek için kullanılan bu geleneksel yöntem çok az değişikliğe uğramıştır. Bu makalenin temel argümanı, istihbarat kurumları tarafından kullanılan bu geleneksel yöntemin terörist örgütlerden kaynaklı tehditleri değerlendirmede çok basit kaldığıdır. Bu çalışma, istihbarat analizindeki geleneksel ve ana yaklaşımı analiz etmekte olup iki parametrenin de önemli olduğuna, fakat terörist örgütlerin tehdit değerlendirmesinde yetersiz kaldığına vurgu yapmaktadır. Terörizm tehdidinin değerlendirmesindeki analitik problemi göstermek için 9/11 terör saldırısı eleştirel bir şekilde incelenmiştir.
DEFEATING COMMUNIST INSURGENCY: THE LESSONS OF MALAYA AND VIETNAM
Authors: BERK Mehmet Burak
Published: May 2020

Sir Robert Thompson, 1916-1992 yılları arasında yaşamış İngiliz askeri subayı ve ayaklanmalara karşı koyma uzmanıdır. Alanında birçok çalışma gerçekleştirmiş olan Thompson, Mao Zedong’un kır gerillası ayaklanma tekniği üzerinde dünyanın önde gelen uzmanlarından biri olarak anılmaktadır. Kitabın önsözünde Thompson, Malaya’da 1948-1960 yılları arasında kaldığı süreçte “Malayan Emergency” olarak bilinen olağanüstü hal döneminde görev aldığı İngiliz İstişâri Misyonu yöneticisi pozisyonu dolayısıyla kişisel tecrübelerini anlatacağından bahsetmektedir.
15 bölümü bulunan kitapta; Malaya’da gerçekleşen olağanüstü hal ortamı, komünist ideolojinin yayılması süreci, ayaklanma süreci, ayaklanmalara karşı koyma prosedürünün temel ilkeleri, hükümetin etkisi, idari yapı, istihbarat alanı, dönemin bilişim hizmetleri, güçler dengesi, temel operasyon konsepti, stratejik köyler –hamlets-, gerillanın izole edilme süreci, orman ve hudut alanı, içerisinde bulunduğu danışmanlık rolü ve son olarak durumun genel değerlendirmesinin yapıldığı bölümlerden oluşmuştur.
A STUDY OF THE CHANGING CONSUMER BUYING BEHAVIOUR IN ORGANISED RETAILING IN LUCKNOW CITY
Authors: Ahmad Zubair
Published: May 2020

The major factor of consumer behaviour in organised retailing is the changing buying behaviour. Various management thinkers have conducted several studies to understand the relationship of buying behaviour and organised retailing. Consumer behaviour is defined as the behaviour that consumers display in searching for, purchasing, using, evaluating and disposing of products and services that they expect will satisfy their needs. (L.G. Schiffman, L.L. Kanuk, 2005). Consumer buying behaviour is changes due to organised retailing sector which introduce in India in 2000 year. Slowly organised retail flourish in India year after year and till 2008 many malls and other hypermarkets open in many cities of India. In this sector some Indian players took the initiative and open their retail chains. For example Future Group opened Big Bazaar, RPG Group opened Spencer Store, Ruia Group opened Shoppers Stop in many cities Now-a-days employees have been hired, trained and remunerated in organised sector. In this respect the malls and hypermarkets provide job opportunities to many people in the country. The organised retailing changes a lot the “consumer buying behaviour” in the country. Under one roof the whole items related to each category available to the consumers in the shops. Times have changed people want a good shopping experience and this experience they feel in purchasing the products from malls, hypermarkets etc. The purpose of this study was to identify through hypothesis testing how consumer buying behaviour changes in organised retailing. The study was conducted using structured questionnaire on private and public sector employees. Chi- Square technique was applied and chi value was computed to test the formulated hypothesis in order to find relevance of consumer buying behaviour in organised retailing.
MOODY’S CHANGE RATING: BUT A LONG DUE, WHAT IS NEXT?
Authors: Neeraj Mahavir
Published: May 2020

Any decision of the government does widely affect an economy because these decisions are affecting the sentiments of a local investor as well as a foreign investor. The economic and structural reforms to boost the growth of the country were taken by the Indian government from last many years. This is the result of institutionalized reforms, that MOODY’S INVESTOR SERVICE upgrades the rating of Indian sovereign bond from Baa3 to Baa2. MOODY'S also changed the outlook of the Indian economy from positive to stable. The rating agency doesn’t upgrade rating of any economy merely some step those are beneficial for a nation in short-term, but rating agency keeps in mind such measure of government that will benefit the economy for a long time. Last time Moody’s upgrade Indian rating in 2004. The current upgrade comes after 13 years. So, it is a long overdue. This research paper is based on a conceptual study. Secondary data is used in this paper and the data is collected from newspapers, magazines, and internet. In this research paper, I investigate, why Moody’s take a long time? And what is next step for the government to maintain or further upgrade the rating of India?
PLASTIC MONEY: PROSPECTIVE AND CHALLENGES
Authors: Mukaria Bhawna
Published: May 2020

In present era, it is impossible to imagine modern bank transactions, commercial transactions and other payments without using the plastic cards. Plastic currency is now gradually becoming a necessity across the globe as more and more developed countries are opting for plastic compared to paper as there are several inherent advantages. The growing involvement of smart phones has made technology applications much more accessible to users. The Government also move forward for a “Digital India” and its focus on growing electronic payments is significant drivers of growth in replacing physical payments with technologybacked solutions. India is at the stage of an amazing shift towards electronic money from traditional cash. For instance the Pradhan Mantri Jan Dhan Yojana (PMJDY), is slowly building recognition among people to move from paper to electronic money. The PMJDY alone has seeded over 150 million Rupay cards in the last year, in addition to the 400 million debit cards already in circulation. There is still emergence for significant increase in the usage of debit cards in the years to come as card. This paper focus on the challenges and future prospects of plastic money in India.
THE ANALYSIS OF LOCAL OSCILLATION IN THE GAS TURBINE GENERATOR CONNECTTO POWER GRID SYSTEMS USE LINEAR OBSERVER
Authors: Hoang Mai Nguyen , Dung Tran van
Published: May 2020

The low frequency oscillation in the electrical generator connect to power grid is an important problem to control systems, especially in the gas turbine generators with high speed. The oscillation makes affect to life time, finance of operating and effect of energy process. There are many cause of the oscillation in governor speed control of power plants. They use PSS to do damping low frequency oscillation in recently [11], [12], [13], [14], [22], [23]. So PSS usually does process with delay cycle time, therefore it makes effect isn’t good result. This paper presents a method using linear in the gas turbine generator, which connects to power grid. By observe affect action of local oscillation of the power, study finds key point of oscillation time. From that, we take out decision to do prediction of damping in system and supply signal in to PSS to reduce damaging of this oscillation. Simulation results explain difference action of the system with linear observer and system without linear observer.
CLASSIFICATION OF BIOMEDICAL IMAGES USING CONTENT BASED IMAGE RETRIEVAL SYSTEMS
Authors: Zhang Yinghui , Zhang Fengyuan , Cui Yantong , Ning Ruoci
Published: May 2020

Because of the numerous application of Content-based image retrieval (CBIR) system in various areas, it has always remained a topic of keen interest by the researchers. Fetching of the most similar image from the complete repository by comparing it to the input image in the minimum span of time is the main task of the CBIR. The purpose of the CBIR can vary from different types of requirements like a diagnosis of the illness by the physician, crime investigation, product recommendation by the e-commerce companies, etc. In the present work, CBIR is used for finding the similar patients having Breast cancer. Gray-Level Co-Occurrence Matrix along with histogram and correlation coefficient is used for creating CBIR system. Comparing the images of the area of interest of a present patient with the complete series of the image of a past patient can help in early diagnosis of the disease. CBIR is so much effective that even when the symptoms are not shown by the body the disease can be diagnosed from the sample images.
INVESTIGATION OF COUNTER-CURRENT FLOW LIMITATION FOR AIR-WATER IN A PWR HOT LEG EXPERIMENTAL LOOP FOR DIFFERENT GEOMETRY
Authors: Morghi Youssef , Puente Jesus , Mesquita Amir , Baliza Ana
Published: May 2020

Gas/liquid two-phase stratified flows in horizontal channels are frequently encountered in nuclear reactors, oil and gas pipelines, steam generators, refrigeration equipment, reflux condensers, packed columns, and heat pipes. The phenomenon known as countercurrent flow limitation, or flooding, is the limiting condition where the flow rates of neither the gas nor the liquid can be further increased without changing the flow pattern. This is the condition where the maximum air mass flow rate at which the down-flowing water mass flow rate is equal to the inlet water mass flow rate. This limiting condition, also known as onset of flooding, can occur in vertical or horizontal geometry. This work is a review of recent experimental investigations of countercurrent flow limitation (CCFL) for various hot-leg geometries of pressurized water reactors (PWRs). We compare results with those obtained from the Nuclear Technology Development Centre (CDTN) in 2005. Recent experimental results in the literature are in good agreement with the 2005 findings.
Performance of Levenberg-Marquardt Algorithm in Backpropagation Network Based on the Number of Neurons in Hidden Layers and Learning Rate
Authors: Mustafidah Hindayati , Suwarsito Suwarsito
Published: May 2020

One of the supervised learning paradigms in artificial neural networks (ANN) that are in great developed is the backpropagation model. Backpropagation is a perceptron learning algorithm with many layers to change weights connected to neurons in hidden layers. The performance of the algorithm is influenced by several network parameters including the number of neurons in the input layer, the maximum epoch used, learning rate (lr) value, the hidden layer configuration, and the resulting error (MSE). Some of the tests conducted in previous studies obtained information that the Levenberg-Marquardt training algorithm has better performance than other algorithms in the backpropagation network, which produces the smallest average error with a test level of α = 5% which used 10 neurons in a hidden layer. The number of neurons in hidden layers varies depending on the number of neurons in the input layer. In this study an analysis of the performance of the Levenberg-Marquardt training algorithm was carried out with 5 neurons in the input layer, a number of n neurons in hidden layers (n = 2, 4, 5, 7, 9), and 1 neuron in the output layer. Performance analysis is based on network-generated errors. This study uses a mixed method, namely development research with quantitative and qualitative testing using ANOVA statistical tests. Based on the analysis, the Levenberg-Marquardt training algorithm produces the smallest error of 0.00014 ± 0.00018 on 9 neurons in hidden layers with lr = 0.5. Keywords: hidden layer, backpropogation, MSE, learning rate, Levenberg-Marquardt.
Pullout strength behaviour of self-compacted concrete in aggressive solutions
Authors: Sabhan Maha , Al-Sibahy Adnan
Published: May 2020

The aim of this study was to investigate the pullout strength behaviour of self-compacted concrete under corrosion conditions. Block samples with two configurations were formulated. A total number of twelve block samples in addition to 24 cubes were tested. The hardened concrete samples were either cured in tap water or exposed to salt solution. A suitable epoxy was used for coating part of the formulated samples. The preliminary mechanical properties and the rate of corrosion were firstly measured, the pullout was then carried out. A comparison was also made with the relevant code of practice. The results obtained showed that both compressive strength and density features exhibited a notable increase at an early age when the samples are exposed to salt solution. The adverse effect of such curing condition appeared at the later ages when the corrosion rate became more intensive. The highest decrease in the value of pullout strength was observed for the reinforced concrete block samples containing epoxy coating reaching to 44.5% less than those cured in tap water.
PENGEMBANGAN SUMBER BELAJAR GEOMETRI SMP BERBASIS ETNOMATEMATIKA UNTUK MENINGKATKAN KARAKTER
Authors: A. M Abi , N. J. M Gella
Published: May 2020

Pembelajaran kontekstual menjadi isu penting karena melibatkan budaya peserta didik. Etnomatematika menjadi salah satu solusi untuk menjawab kebutuhan tersebut terutama pada materi geometri. Penelitian ini adalah Research and Development (R & D) model Borg & Gall menggunakan pre-experimental one group pretest-posttest design. Tujuan penelitian ini adalah untuk menguji kevalidan, kepraktisan dan keefektifan penggunaan sumber belajar. Penelitian ini dilakukan di SMP Negeri 2 Amanuban Barat kelas VIII tahun ajaran 2017/2018 pada materi geometri. Hasil penelitian menunjukkan bahwa sumber belajar yang dikembangkan berkategori valid, praktis dan efektif. Kevalidan sumber belajar sebesar 98% sedangkan kepraktisannya  sebesar 96% ditunjukkan dengan respon positif peserta didik dan guru. Keefektifan sumber belajar dilihat dari perbedaan prestasi belajar yang signifikan antara kelas eksperimen dan kontrol. Peningkatan prestasi belajar setelah implementasi sebesar 0,6 dilihat dari skor gain.
ANALISIS FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN TERJANGKITNYA PENYAKIT MALARIA DENGAN MENGGUNAKAN MODEL REGRESI LOGISTIK BINIMIAL
Authors: V. Babo Margareta , A. Dwiatmoko Ig.
Published: May 2020

Topik yang dibahas dalam penelitian ini adalah aplikasi model regresi logistik dalam bidang kesehatan. Analisis regresi logistik merupakan model regresi yang digunakan bila variabel Y bersifat kualitatif yang hanya terdiri dari dua kategori. Bentuk umum model regresi logistik dengan  variabel bebas yakni

 . Dengan  adalah 2.718,  adalah koefisien regresi dari variabel bebas ke-j,  adalah nilai variabel bebas ke-j dengan j=1,2,...,  dan  adalah konstanta. Model regresi logistik bersifat nonlinear terhadap parameter dan dapat diubah dalam bentuk linear terhadap parameter dengan menggunakan transformasi logaritma dan dapat dinyatakan dalam bentuk; . Dengan , dengan  dan  diduga menggunakan Metode Kemungkinan Maksimum.
PENGGUNAAN MEDIA GAMBAR MOTIF TENUN BUNA UNTUK MENINGKATKAN PRESTASI BELAJAR MATEMATIKA SISWA SMPN 4 KUPANG TAHUN PELAJARAN 2016/2017
Authors: Nainaban Anastasia
Published: May 2020

Tujuan dari penelitian ini adalah untuk mengetahui peningkatan prestasi belajar matematika siswa kelas VIIB SMP Negeri 4 Kupang dengan penggunaan media gambar motif tenun buna. Jenis penelitian yang digunakan adalah penelitian tindakan kelas. Subjek penelitian adalah siswa Kelas VIIB SMP Negeri 4 Kota Kupang berjumlah 32 yang terdiri dari 14 orang laki-laki dan 18 orang perempuan. Penelitian dilaksanakan dalam 2 siklus. Teknik analisis data menggunakan tekni deskripsi kualitatif. Pengumpulan data dalam penelitian ini dilakukan melalui observasi dan tes. Observasi dilakukan pada saat pembelajaran berlangsung dalam setiap siklus, sedangkan tes dilakukan pada akhir pembelajaran dalam setiap siklus. Hasil penelitian menunjukkan adanya peningkatan prestasi belajar siswa setelah penggunaan media gambar motif tenun buna dalam pembelajaran. Hal ini terlihat dari meningkatnya hasil tes yang diberikan pada akhir setiap siklus, dimana nilai rata-rata tes siklus I mencapai 76,09 dengan persentase ketuntasan belajar secara klasikal 68,75% dan pada hasil tes siklus II nilai rata-rata meningkat menjadi 83,12 atau meningkat sebesar 7,03 dengan persentase ketuntasan belajar secara klasikal mencapai 90,62% atau meningkat sebesar 21,87%. Dari data tersebut dapat disimpulkan bahwa penggunaan media gambar motif tenun buna dalam pembelajaran matematika materi belah ketupat dapat meningkatkan prestasi belajar siswa.
PENGARUH MODEL PEMBELAJARAN MATEMATIKA REALISTIK TERHADAP KEMAMPUAN PEMECAHAN MASALAH MATEMATIKA SISWA SMP
Authors: Logo Tamar B. , R. Rowa Yohana , Uskono Irmina V.
Published: May 2020

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran matematika realistik terhadap kemampuan pemecahan masalah matematika siswa SMP. Jenis penelitian yang digunakan adalah penelitian kuantitatif dengan metode experimental dengan desain penelitian one group pretest-posttest design. Adapun populasi dalam penelitian ini yaitu seluruh kelas VII disalah satu SMPN di kota Kupang, sedangkan sampel dalam penelitian ini yaitu kelas VIIF yeng berjumlah 30 siswa yang dipilih menggunakan Teknik Simple Random Sampling. Instrumen yang digunakan untuk mengukur kemampuan pemecahan masalah matematika siswa SMP berupa test  Essay yang berjumlah 3 soal. Teknik analisis data yang digunakan yaitu uji t. Data yang digunakan dalam penelitian yaitu data nilai pretest dan data nilai posttest dari kelas eksperimen yang diajarkan dengan menggunakan model pembelajaran matematika realistik  terhadap kemampuan pemecahan masalah matematika siswa SMP. Berdasarkan hasil observasi dan penacapaian indikator, pelaksanaan pembelajaran dengan menggunakan model PMR terhadap kemampuan pemecahan masalah matematika siswa SMP tergolong sangat baik. Uji t menunjukkan thitung = - 17,576 dan ttabel =- 2,045 pada taraf signifikan  5% yang berarti ada pengaruh yang signifikan pada model pembelajaran matematika realistik terhadap kemampuan pemecahan masalah matematika siswa SMP.
Participation in the World War I and Lester Pearson’s Views Transformation
Authors: Pokrovskaya Dar'ya Mikhailovna
Published: May 2020

Canada’s participation in world politics is often associated with the notion of liberal internationalism as the main tool of conducting the Canadian foreign policy. One of the originators of this idea is considered to be the diplomat and prime minister Lester Bowles Pearson. The article analyses the diplomat’s views transformation during the World War I. The author substantiates the necessity of studying Pearson’s views by significance of his contributions to the development of the Canadian national and foreign policies, as well as to the international relations of the mid-20th century. It is argued that it was during his participation in the Great War when the concepts of war and peace developed in Pearson’s mind. The study has also identified sociopolitical conditions under which the formation and further transformation of Lester Pearson’s views on the use of force in world politics took place.
Modern Urban Woman’s Costume of Dagestan Peoples as a Component of the North-Caucasian Regional Fashion
Authors: Zul'pukarova El'mira Magomed-Gereevna , Seferbekov Ruslan Ibragimovich
Published: May 2020

The paper aims to study the modern urban woman’s costume of Dagestan peoples. The authors consider ecological, economic and cultural, ethno-cultural, gender, social-demographical, confessional and professional peculiarities, preferences and restrictions, regarding such issues as group and peculiar subculture, dress code and remaining elements of traditional national clothes. Scientific originality of the paper lies in the fact that the researchers analyze the modern urban woman’s costume, identify elements of traditional mountaineers’ clothes in it and reveal common and specific features of Dagestan trend of the North Caucasian regional fashion. Thus, functions, details and peculiarities of the urban woman’s costume allow concluding on existence of Dagestan woman’s fashion - an inherent component of the North Caucasian regional fashion.
Memphite Sacerdotal Decree: Comments
Authors: Panov Maxim Vyacheslavovich
Published: May 2020

The second part of the study, devoted to the decree of the Egyptian priests, adopted in Memphis in 196 BC. Parallels and major differences of three text versions: hieroglyphic, Demotic and Greek, are discussed. Variation in introducing toponyms is defined; specifics in referring to the three writing systems in ancient times are indicated; different implications in introducing Ptolemy’s V name and his epitheta are analyzed. Two improvements for the hieroglyphic text edited by K. Sethe (stela Nebireh, lines 21-22) are made; a new interpretation of the disputable word in the Demotic version of the Rosetta stone, line 28 proposed as a preposition.
The German Public Diplomacy Discourse (2014-2019)
Authors: Kuzina Oksana Evgen'evna
Published: May 2020

The paper aims to identify specificity of public diplomacy understanding among the basic German actors in the period from 2017 to 2019. The article presents an overview of the German-language publications on this issue some of which were previously unknown in the Russian scientific circles. Analysing the latest conceptions, strategies, reports and other official publications of the basic actors of the German public diplomacy, the author evaluates relevance of the acquired information. Scientific originality of the study involves introducing the author’s definition of the modern German public diplomacy taking into account its typical features identified during the research. The author concludes that recent practical activity of a wide range of the German public diplomacy institutions influences formation of its conceptual foundations.
Barack Obama’s “Pivot to Asia” and the Issue of Strengthening Transatlantic Relations
Authors: Pokudov Zakhar Vasil'evich , Kalimonov Il'dar Kimovich
Published: May 2020

The study aims to analyse the impact that Barack Obama’s “pivot to Asia” had on the development of transatlantic relations. The article traces the premises of such a “pivot” on the part of the USA, as well as the European Union’s reaction to it. Moreover, the paper examines difference in military-political approaches of the European Union and the USA to the Southeast Asian Region. The study is novel as, despite the fact that there are many works devoted to studying transatlantic relations, there has been no research that would analyse their development from the perspective of forming relations with another region. Furthermore, a wide range of new foreign sources and references will be introduced into the Russian scientific discourse. The results prove that the Southeast Asian Region holds both economic and military-political interests for the USA, whereas the European Union considers the region from the geo-economic point of view. Differences in the approaches adopted by the European Union and the USA may further divide the NATO due to progressively diverging military-political goals of the European and the American parts of the alliance.
Protest Movement in the Czechoslovak Corps and Irkutsk Extraordinary Congress at the Final Stage of the Russian Civil War
Authors: Vasil'chenko Maksim Anatol'evich , Panin Evgenii Valer'evich
Published: May 2020

The paper aims to study protest movement in the Czechoslovak Corps in the years of the Civil War in Russia. Scientific originality of the research lies in the fact that the authors examine causes for protest moods formation among the Corps personnel who played a key role in confrontation escalation in Russia. The soldiers and officers’ discontent is a poorly investigated factor that incited mutiny of the Czechoslovak Corps in May, 1918. The article considers Irkutsk Extraordinary Congress - the most vivid manifestation of the soldiers and officers’ disagreement with the command’s actions. Conclusions are made that protest movement and Irkutsk Congress influenced the decision of the Allied Forces Headquarters in Siberia about the soldiers evacuation through Vladivostok and refusal to interact with A. V. Kolchak’s troops.
Socially Oriented Non-Profit Organisations and Youth Associations as Factor of Youth’s Civic Consciousness Formation
Authors: Velikodnyaya Ekaterina Maksimovna , Zadvornyak Alisa Denisovna , Cherepanova Ekaterina Sergeevna
Published: May 2020

The article analyses the issue of youth’s civic consciousness formation in the face of new emerging communication formats. The topic of youth’s civic consciousness formation is one of the most relevant and requires comprehensive scientific analysis. The study aims to determine how modern subjects of the civil society - non-profit socially oriented organisations and public associations - affect youth’s acquisition of civic values. Argumentation is carried out by means of the data collected through an empirical research conducted by the authors in 2019.
Ethicalisation of Engineering in the Age of Digitalisation
Authors: Kal'va Inna Sergeevna , Dyagileva Tat'yana Vladimirovna
Published: May 2020

The aim of the study is to determine specifics of engineering, which is treated as a sociocultural phenomenon influencing changes in political, economic, social life of the society. It is proven that a change of an engineer’s status throughout scientific history depends on a degree of the technosphere development. The study is novel in that it defines the content of the notion “digital engineer” used to denote a personality type of an engineer, which is characterised by a combination of professional and informational competences, the latter being among the crucial ones in the age of digitalisation. The results have proven that it is necessary to teach the principles of engineering ethicalisation to students for further successful development of the society.
Religious Identity in Foreign Research: Constructivist Approach
Authors: Idrisov Azamat Zhambulatovich
Published: May 2020

The article is devoted to analysing the constructivist approach in studying the origin and formation of religious identity. The aim of this study is to review the theoretical research based on the constructivism methodology, which explains the individual and collective aspects of religious identity and its place in foreign social and religious studies. By analysing the constructivist approach to studying national and ethnic identity it was found that this methodological approach is also relevant to the study of religious identity, which makes this research novel. The paper concludes that identity is interpreted in foreign works as a way of constructing social reality.
G. V. Chernov’s Adaptation of N. A. Rimsky-Korsakov’s “The Battle of Kerzhenets” for the Russian Folk Orchestra: Timbre and Textual Peculiarities of the Score
Authors: Romashkova Ol'ga Nikolaevna , Romashkov Anatolii Anatol'evich
Published: May 2020

The authors consider specificity of folk instrumental interpretation. By the example of instrumentation of N. A. Rimsky-Korsakov’s “The Battle of Kerzhenets” score, the paper examines difficulties that occur while adapting symphonic music for the Russian folk orchestra. Special attention is paid to analysing tutti and solo parts in the score of the folk orchestra version. The techniques to adapt symphonic score for the Russian folk orchestra are revealed.
Annexation of the Crimea by Catherine the Great as a Way of Solving the State’s Historical Tasks in the Second Half of the XVIII Century
Authors: Zherebkin Mikhail Vasil'evich
Published: May 2020

The article presents an analysis of the reasons on account of which Catherine the Great made a decision to annex the Crimea in April of 1783. The author examines the circumstances under which Russia was objectively bound to access the Black Sea coast and annex the Crimean Peninsula that allowed establishing the southern border within its natural boundaries. The annexation of the Crimean Peninsula offered new opportunities of developing trade relations with Europe, as well as protecting the state in the south and increasing its prominence in the Black Sea region.
Architectural Specifics of Iran Sunni and Shia Mosques
Authors: Aysan Daroudi
Published: May 2020

The study aims to examine impact of Iran religious beliefs on architectural and spatial structure of the Muslim temple buildings belonging to the Sunni and Shia religious denominations. The work is devoted to analysing, for the first time in science, the volume-spatial composition of the Shia mosques compared to that of the Sunni ones in Iran architecture. The article is novel in that it studies architectural specifics dictated by peculiarities of the Sunni and Shia cults. The results show that the main distinctive feature separating the Shia mosques from the Sunni ones is precise organisation of believers’ movements inside a mosque achieved by a number of architectural techniques reviewed in the article.
Mental Models of Image Transformation in Symbolic Space of Drama-Tale (by the Material of the Plays “The Sunken Bell” by G. Hauptmann and “Ariane and Bluebeard” by M. Maeterlinck)
Authors: Alesenkova Viktoriya Nikolaevna
Published: May 2020

The paper aims to identify archetypal models of image transformation (mental schemes) by the material of a symbolist drama-tale. The article provides a cognitive analysis of space and its interaction with personages in the plays “The Sunken Bell” by G. Hauptmann and “Ariane and Bluebeard” by M. Maeterlinck. Scientific originality of the study lies in the fact that the accent is shifted from the analysis of the personages’ discrete functions in the story structure to the comprehensive study of the image cyclic development. The findings indicate that mental models of the image transformation represent the dramatists’ metaphysical experience and promote deeper understanding of human soul with the help of art.
Forest Protection Activity of Voronezh Provincial Administration in the Middle of the XIX Century
Authors: Semenova Elena Viktorovna
Published: May 2020

The article considers development of Russia’s forest policy in the middle of the XIX century. Relying on activity of Voronezh provincial administration and archival data, the author analyzes forest protection activity of Voronezh Chamber of State Property, identifies its basic trends, estate specificity and efficiency. Special attention is paid to the problem of the state’s struggle with illegal forest felling. In this connection, the researcher examines the state social policy towards social classes representatives and towards forestry officers.
Estudio de arenas de trituración para el reemplazo de arenas naturales en la elaboración de morteros y hormigones
Authors: Rolny Daiana Gisele , Couyoupetrou Luis , Ontivero Emiliano Pablo , Etcheverry Ricardo , Forte Luís María
Published: May 2020

El hormigón es uno de los materiales de uso más difundido a nivel global. Su empleo, demanda grandes volúmenes de recursos naturales no renovables y elevados consumos de energía.

 
El desarrollo sustentable como responsabilidad social universitaria experiencias en la FAU de la UNT
Authors: Saleme Horacio , Aráoz Soledad
Published: May 2020

La Universidad Nacional Tecnológica de Tucumán (UTN) fue inaugurada en 1914. Sus fundadores se alejaron de los modelos tradiciones de entonces latinos y napoleónico dando al mundo una nueva concepción de universidad, volcada a actuar intensamente en el medio que la sustenta.

 
Tecnología y ambiente. Propuesta pedagógica dentro de la carrera de arquitectura FADU UNL
Authors: Maidana Alberto , Pérez Manuel , Bruschini César , Armelini Griselda
Published: May 2020

La asignatura “Tecnología y ambiente: una mirada a la arquitectura sustentable”, surge en el año 2011 como consecuencia de la instrumentación en la FADU UNL de un nuevo plan de estudio al cual se le incorporan materias con carácter de optativas y electivas como oferta abierta al alumno y que le permite a lo largo de la carrera indagar y profundizar sobre temas de su interés, que pueden o no tener pertenecer a los contenidos de grado.
More than impossible: negative and complex probabilities and their philosophical interpretations
Authors: Penchev Vasil
Published: May 2020

A historical review and philosophical look at the introduction of “negative probability” as well as “complex probability” is suggested. The generalization of “probability” is forced by mathematical models in physical or technical disciplines. Initially, they are involved only as an auxiliary tool to complement mathematical models to the completeness to corresponding operations. Rewards, they acquire ontological status, especially in quantum mechanics and its formulation as a natural information theory as “quantum information” after the experimental confirmation the phenomena of “entanglement”. Philosophical interpretations appear. A generalization of them is suggested: ontologically, they correspond to a relevant generalization to the relation of a part and its whole where the whole is a subset of the part rather than vice versa. The structure of “vector space” is involved necessarily in order to differ the part “by itself” from it in relation to the whole as a projection within it. That difference is reflected in the new dimension of vector space both mathematically and conceptually. Then, “negative or complex probability” are interpreted as a quantity corresponding the generalized case where the part can be “bigger” than the whole, and it is represented only partly in general within the whole.
Fbxo6 is a differentially expressed gene in the blood of patients with Crohn’s Disease.
Authors: Mamoor Shahan
Published: May 2020

We used published microarray datasets (1-3) to compare global gene expression profiles in whole blood, from patients with Crohn’s Disease and from healthy control subjects. We identified the F-box protein 6 Fbxo6 as differentially expressed in the peripheral blood of patients with Crohn’s Disease. Patients with Crohn’s Disease expressed significantly higher levels of mRNA for FBXO6 protein in the peripheral blood than did control subjects.
Legionnaire’s disease and COVID-19: Could Legionella be acting in conjunction with the Corona virus to aggravate the COVID-19 disease?
Authors: PENDERY Andrew John
Published: May 2020

There are some striking similarities between Legionnaire’s disease and COVID-19. Thesymptoms, age group and sex at risk are identical. The geographical distribution of both diseases is similar in Europe overall, and within the USA, France and Italy. The environmental distributions are also similar. However Legionnaire’s disease is caused by Legionella bacteria while COVID-19 is caused by the Corona virus. Whereas COVID-19 is contagious, Legionnaire’s disease is environmental. Legionella bacteria are commonly found in drinking water systems and near air conditioning cooling towers. Legionnaire’sdisease is caught by inhaling contaminated water droplets. The Legionella bacteria does not spread person to person and only causes disease if it enters the lungs.Could the Corona virus be making it easier for Legionella bacteria to enter the lungs?