bluuebunny/crossref_metadata_2025 huggingface dataset:
MENSURAÇÃO DA APTIDÃO AERÓBIA ATRAVÉS DOS TESTES DE 12 MINUTOS E VELOCIDADE CRÍTICA APÓS OITO SEMANAS DE TREINAMENTO AERÓBIO EM MILITARES
Authors: Beck Wladimir Rafael , Zagatto Alessandro Moura
Published: November 2020

A utilização de protocolos não invasivos para a avaliação e prescrição de exercícios tem sido muito importante nos últimos anos. No entanto, poucos são os estudos que analisam os efeitos de um treinamento sistematizado sobre as variáveis destes protocolos. Com isto, o objetivo deste estudo foi o de verificar o efeito do treinamento aeróbio de oito semanas na intensidade correspondente à velocidade crítica (VCrit) nas performances de 400, 800, 1600 e 2800 metros e aptidão aeróbia, mensuradas pelos testes de 12 minutos e VCrit. Participaram do estudo 10 militares do sexo masculino, moderadamente ativos, com idades correspondentes a 22,4±2,3 anos, estatura de 176±0 cm, massa corporal de 79,9±13,1 kg, percentual de gordura de 20,2±8,3%, índice de massa corporal de 25,8±4,2 kg.m-2, e consumo máximo de oxigênio predito de 48,5±6,9 ml.kg-1.min. Todos foram submetidos ao teste de VCrit (cargas preditivas nas distâncias de 400, 800, 1600 e 2800 metros) e 12 minutos antes e após o treinamento. o treinamento consistiu em corrida com duração de 20 minutos por dia, três vezes por semana e intensidade correspondente à VCrit. Após o treinamento foram encontradas melhoras significativas nas intensidades correspondentes à VCrit, de 6% (p=0,03), assim como nas performances de 400, 1600 e 2800m, e na distancia total percorrida no teste de 12 minutos (D12min) após o treinamento, com um incremento nesta variável de 4,7% (p=0,01). Desse modo, podemos concluir que o treinamento aeróbio sistematizado de oito semanas na intensidade de VCrit, parece promover alterações significativas nesse parâmetro, assim como melhorar significativamente as performances de 400, 1600, 2800m e D12min.
INFLUÊNCIA DA FLEXIBILIDADE NO DESEMPENHO EM SALTOS VERTICAIS
Authors: Couto Bruno Pena , Silva Hosanna Rodrigues , Cunha Caroline Regiane , Cotting Flávia Mansur de Aguiar , De Alcântara Natália Vitor
Published: November 2020

Alguns estudos apontam que indivíduos com unidades músculo-tendíneas com menor amplitude de movimento são capazes de utilizar melhor a energia elástica armazenada na estrutura do tendão em movimentos que envolvem as ações excêntrica e concêntrica. Assim, o objetivo desse estudo foi verificar a influência da flexibilidade de membros inferiores na diferença de desempenho entre o salto Squat Jump (SJ) e o salto Countermovement Jump (CMJ). Doze voluntários do gênero masculino foram submetidos à goniometria de membros inferiores, para avaliação da flexibilidade, na qual foram mensuradas a amplitude de movimento em flexão e extensão de quadril e em dorsiflexão. Posteriormente, foram realizados os testes de saltos verticais e determinada a diferença de desempenho entre os resultados do SJ e os resultados do CMJ. Foi encontrada uma alta correlação inversa (r= -0,81, p<0,05) entre a amplitude de movimento na flexão de quadril e a melhora do desempenho do SJ para o CMJ. Para a extensão de quadril e dorsiflexão foi encontrada baixa correlação inversa (r = -0,45 e r = -0,26 respectivamente, p<0,05). Diante destes resultados foi possível concluir que há um maior aumento do desempenho entre os saltos SJ e CMJ em indivíduos com menor ADM na flexão de quadril. Estes resultados sugerem que indivíduos com menor flexibilidade nos músculos extensores do quadril possuem um maior aproveitamento da energia elástica armazenada durante a ação excêntrica no CMJ.
ESTUDO SOBRE A VISÃO NO ESPORTE: O CASO DO FUTEBOL E DO FUTSAL
Authors: Marques Junior Nelson Kautzner
Published: November 2020

O funcionamento da visão é complexo, mas vários cientistas do esporte investigam sobre esse tema porque diversas tarefas das modalidades dependem da visão para uma boa execução. A maioria dos estudos sobre a visão no esporte acontecem no futebol. Talvez isso ocorra porque a literatura do futebol e dos seus derivados recomendam na partida ênfase na visão periférica. O objetivo da revisão foi de apresentar os estudos sobre a visão no futebol e no futsal. Foram selecionados cinco estudos, quatro sobre o futebol e um sobre o futsal. A primeira investigação mostrou como a visão atua numa tarefa defensiva, o segundo estudo evidenciou a percepção visual, na terceira pesquisa foi estudado o pênalti e no quarto estudo sobre o futebol foi abordado o conhecimento do resultado e a visão. A única investigação sobre o futsal foi sobre o aprendizado neuromotor, os atletas tiveram aquisição do treino da visão periférica. Em conclusão, pesquisar a visão no futebol e no futsal é importante porque o atleta desse esporte precisa jogar de cabeça erguida.
EFEITO DE TREINAMENTO EM MINI-TRAMPOLIM EM SOLO E EM ÁGUA: BENEFÍCIOS ANTROPOMÉTRICOS, ATLÉTICOS E DE QUALIDADE DE VIDA
Authors: Alonso Paula Tatiane , Anjos Tatiana Coletto , Leite Juliana Paula , Gonçalves Aguinaldo , Padovani Carlos Roberto
Published: November 2020

Resumo: O objetivo deste estudo foi explorar o efeito de programa no mini-trampolim em solo e na água sobre variáveis antropométricas (peso; índice de massa corpórea; circunferência de cintura, quadril e relação entre estas; média dos valores das dobras cutâneas supra-ilíaca, subescapular e da coxa; percentual de massa gorda e magra), atléticas (salto com e sem auxílio dos membros superiores, flexibilidade, consumo e absorção de oxigênio, freqüência cardíaca logo após o repouso, resistência muscular localizada de membros inferiores, superiores e abdominais) e os domínios de qualidade de vida. Os exercícios eram coreografados e realizados durante 16 semanas de duração, três vezes semanais, com 45 minutos. Foram avaliadas, nos momentos pré e pós intervenção, 46 mulheres jovens, sedentárias, entre 19 e 35 anos de idade (média de 23,97±4,06), divididas em dois grupos. Aplicou-se a técnica da análise de variância não-paramétrica para medidas repetidas em grupos com dois fatores, sendo um deles dependente. A associação entre o conjunto de variáveis, em cada grupo, foi investigada pela técnica multivariada de interdependência, apresentada pela função e carga canônica. Observou-se significância estatística (5%) nas relações entre ambos os grupos de variáveis com os domínios de qualidade de vida físico (p<0,05); psicológico (p<0,0001); social (p<0,01) e ambiental (p<0,005) na modalidade aquática, enquanto que, na terrestre, o mesmo não ocorreu. No entanto, na impossibilidade de adotar-se a primeira alternativa, a segunda não deve ser desconsiderada, pois aí também diferenças significativas foram registradas na comparação antes e após intervenção nos valores individuais das variáveis.
ASPECTOS MORFOLÓGICOS E FISIOLÓGICOS NO CICLISMO DE ESTRADA E MOUNTAIN BIKE CROSS-COUNTRY
Authors: Costa Vitor Pereira , Oliveira Fernando Roberto de
Published: November 2020

As competições de ciclismo podem ser divididas basicamente em dois formatos: contra-relógio e estrada. Já o Mountain Bike (MTB) é caracterizado por ser disputado em diferentes tipos de trilhas e estradas de terra. Na tentativa de sintetizar os recentes estudos científicos no ciclismo e MTB, foi descrita esta breve revisão sobre aspectos morfofisiológicos de atletas de ambas as modalidades. Percebe-se que os ciclistas especialistas em etapas planas são altos e fortes (variação de 180 a 185 cm de altura, 70 a 75 kg de massa corporal), sendo estatisticamente significativa (p < 0,05) a diferença dos especialistas em montanhas (175-180 cm, 60-66 kg). Especula-se que as características morfológicas dos especialistas em montanhas são semelhantes aos mountain bikers (178 ±0,1 cm de altura, 65,3 ± 6,5 kg de massa corporal, média e desvio padrão). Alguns estudos verificaram que os ciclistas atingiram a potência aeróbia máxima (Wmáx) significativamente mais alta que os mountain bikers em valores absolutos e relativos à massa corporal (p < 0,05). Em contraste, outros demonstraram que os atletas de MTB apresentam a Wmáx e consumo de oxigênio de pico (VO2pico) relativo à massa corporal significativamente mais alto que os ciclistas (P = 0,03). Assim, o conflito relatado na literatura sobre as características morfofisiológicas de ciclistas e mountain bikers, se expande além das diferenças metodológicas encontradas nos estudos, sendo que talvez estejam presentes no nível competitivo e de treinamento dos diferentes atletas investigados. Dessa forma, entendemos que a interpretação das informações apresentadas serve como referências para os treinadores realizarem a prescrição do treinamento de ciclistas e mountain bikers.
INDÚSTRIA CULTURAL E ESPORTE DEVEM SE INTERLIGAR PELA PUBLICIDADE.
Authors: Capinussú José Maurício
Published: November 2020

O presente trabalho objetiva estabelecer um elo entre esporte e indústria cultural, a partir do instante em que ambos norteiam seus procedimentos, dentro de uma visão moderna e realista, sem mascaramentos e hipocrisia, por princípios de comercialização e lucro, naturalmente obedecendo a princípios éticos e morais, sem apelar para expedientes que a sociedade critica condena. Tendo origem na década de 40 (1947) na Alemanha, a indústria cultural teve no berlinense Theodor Adorno o seu grande apologista, segundo ele, representando o estudo da comunicação sob o enfoque dos efeitos sociais de caráter ideológico dos meios de comunicação, efeitos esses que subordinam a ideologia ao princípio de comercialização da informação. A infl uência da indústria cultural, segundo opiniões de intelectuais que se aprofundaram no estudo do problema, pode ser prejudicial para o esporte, exigindo providências capazes de neutralizar este lado negativo, utilizando-se o recurso da publicidade como uma espécie de antídoto, cuja aplicação viria benefi ciar o esporte.
Financial Systems Theory and Control of Finances: The Mediating Role of Psychological Empowerment in the Relationship between Transformational Leadership and Employee Engagement: An Evidence from Vietnam
Authors: Hung Do Quang , Tran Anh Tung , Tran The Tuan
Published: November 2020

Employee engagement has been closely linked to work attitudes (e.g., job satisfaction, intentions to quit, withdrawal), employees' innovation, organizational success and financial performance (e.g., profits, shareholder return) and, therefore, getting much attention from academia and practitioner communities. Additionally, to have a full insight in employees, organizations have to take care of psychological side of employees, which manifests in psychological empowerment. This study investigates the mediating role of psychological empowerment in the relationship between transformational leadership and employee engagement in the context of Vietnam. Data were collected through a survey conducted in Vietnam using 254 respondents who are employees and managers. A researcher-administered questionnaire survey method was used for data collection. The findings reveal that Psychological Empowerment is significantly related with Transformational leadership and Employee Engagement; there is a direct effect of Psychological Empowerment and Employee Engagement; and Transformational leadership not only has a direct impact on Employee Engagement, but also has indirect effect through Psychological Empowerment as a mediating variable. These findings have several implications also for human resource practices in organizations. It is expected that this study provides valuable information to consider in business practice for the development of interventions aimed at mitigating turnover behavior and maximizing organizational performances through an engaged workforce.
Right and Wrong from the Standpoint of G. W. Hegel
Authors:   Russian Academy of Natural Sciences (Moscow), Ershov V. V.
Published: November 2020

The subject of the article is the right and «wrong» from the standpoint of G. W. Hegel and other researchers. H. W. Hegel refers the «wrong» to the «unreal» right, which should «gradually disappear». In the article, first of all, legal and individual regulators of legal relations are distinguished. Secondly, the «wrong» refers to a type of individual regulators of legal relations, which have distinctive objective features from the right.
Consequences of Partial Payment of the Fine Appointed as a Criminal Punishment: «Exceeding» Punishment for Poverty or Favour to Poor Convicts
Authors:   Russian State University of Justice (Moscow), Nikolyuk V. V.
Published: November 2020

Using specific cases of the replacement of a fine imposed by a sentence with another punishment in the case of malicious evasion of the convicted person from paying it, the author analyzes the legal consequences of the partial payment of the fine. It is shown that the court takes in to account the partial payment of the fine by the convicted person, its size in relation to the total amount of the fine determined by the sentence, the time when the funds were paid in to the deposit account of the court. As a general rule, they are taken in to account by the court when declaring (non-declaring) malicious evasion of the convicted from paying the fine.
Problematic Issues of Collection Child Support to Maintenance of Minor Children in Actionproceedings of Civil Justice
Authors:   North-West Branch of Russian State University of Justice (St. Petersburg), Voytovich L. V.
Published: November 2020

Present judicial practice detects a number of problems at trail by court about child support in action proceedings of civil justice. Development procedural legislation and substantive legislation shouldbe carried out takinginto account the fact, that the realization of the rights of the child to the material maintenance should not depend on the discretion of his legal representatives; unacceptable set a ban to collect child support for the previous period on the parent, who did not perform his child care duties; burden of proof respectful circumstances in connection with which one of the parents did not provide material support to the child should assigned to the unscrupulous parent; child support for cancellation of adoption must be enforced and, for the court, it should be an obligation, not a right.
Ensuring the Rights of Administrative Process Subjects in the Practice of Issuing Warnings by the Antimonopoly Authority in Connection with Violations of Antimonopoly Legislation
Authors:   Russian State University of Justice (Moscow), Pisenkо К. А. , Zyuzin V. A. ,   Russian State University of Justice (Moscow)
Published: November 2020

The article is devoted to the development of theoretical approaches to solving the problems of ensuring the rights of administrative process subjects in the practice of issuing prevention acts by the antimonopoly authority in connection with violations of the Antimonopoly legislation. Consideration of actual problems and development of proposals are carried out in the context of judicial practice and the judicial interpretation acts content. The suppressive-restorative nature of prevention acts is defined, for the interests balance ensuring the complex of procedural guarantees providing protection of the control relations subjects rights is offered.
Pengaruh Bimbingan Kelompok Terhadap Harga Diri Siswa Kelas VIII SMP Negeri 6 Kota Gorontalo
Authors: Pautina Mohamad Rizal
Published: November 2020

Harga diri merupakan penilaian individu terhadap dirinya maupun orang lain. harga diri individu dipengaruhi oleh faktor dari luar diri individu dan dari dalam diri individu. Faktor dari luar diri individu terdiri atas: keluarga, guru, teman sebaya, dan tempat kerja. Sedangkan faktor dari dalam diri individu terdiri atas: kepercayaan, amalan, keterampilan pribadi, dan pencapaian. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh bimbingan kelompok terhadap harga diri siswa. Penelitian ini mengunakan metode kuatitatif dengan pendekatan eksperimen semu yang menggunakan desain penelitian “One Group Pre-test and Post-test Design” dengan angket sebagai instrumen pengumpul data. Populasi dalam penelitian ini adalah seluruh siswa kelas VIII SMP Negeri 6 Kota Gorontalo yang berjumlah 378 orang yang terbagi dalam 11 kelas. Sedangkan Yang menjadi sampel dalam penelitian ini adalah siswa kelas VIII yang berjumlah 15 orang yang dipilih dengan teknik purposive sampling. Data dianalisis dengan menggunakan uji statistik (uji t). Dari hasil perhitungan diperoleh harga thitung sebesar -5,52 sedangkan tdaftar pada taraf nyata 5% sebesar 2,05. Ternyata harga thitung memperoleh harga lain, atau harga thitung telah berada diluar daerah penerimaan H0, sehingga dapat disimpulkan bahwa H0 ditolak dan menerima H1. Hal ini berarti bahwa layanan bimbingan kelompok berpengaruh terhadap harga diri siswa.
Penerapan Teknik Kejutan Verbal untuk Meningkatkan Self Esteem Siswa
Authors: Idris Idriani , Ulan Arni
Published: November 2020

Permasalahan Pokok yang dikaji dalam penelitian ini yaitu meningkatkan self esteem siswa dengan Teknik Kejutan Verbal. Tujuan penelitian ini (1) Mengetahui gambaran penerapan teknik kejutan verbal,(2) Mengetahui tingkat self esteem siswa sebelum dan sesudah diberikan teknik kejutan verbal, (3) Mengetahui pengaruh teknik kejutan verbal dalam meningkatkan self esteem siswa. Pendekatan penelitian yang digunakan adalah kuantitatif dengan desain pre-experimental, one group pretest-posttest  design. Populasi dan sampel penelitian ini adalah siswa kelas X SMA Negeri 9 Makassar yang teridentifikasi memiliki self esteem rendah dengan jumlah sampel penelitian sebanyak 9 orang. Instrumen yang digunakan adalah skala dan observasi. Analisis data yang digunakan adalah analisis deskriptif, dan analisis statistik inferensial dengan t-test. Hasil penelitian menunjukkan bahwa: (1) Pelaksanaan teknik kejutan verbal melalui konseling kelompok terdiri dari lima tahap yaitu membangun lingkungan konseling, eksplorasi wants and needs, eksplorasi doing and direction, evaluasi diri serta rencana dan tindakan dimana siswa penuh antusias pada setiap tahap yang dilaksanakan, (2) Tingkat self esteem siswa sebelum diberikan teknik kejutan verbal berada pada kategori rendah kemudian mengalami peningkatan setelah diberikan teknik kejutan verbal yaitu berada pada ketegori sedang, (3) Teknik kejutan verbal berpengaruh signifikan dalam penigkatan self esteem siswa.
Sistem Pendukung Kepututusan Menentukan Kriteria Dosen Terbaik Di Sekolah Tinggi Teknologi Muhammadiyah Cileungsi Metode Simple Additive Weighting
Authors: Nurkholis  , Sukamto Pria , Siswanto
Published: November 2020

Sebagai pendidik profesional dan ilmuwan dosen bertugas mentransformasikan, mengembangkan dan menyebarluaskan ilmu pengetahuan teknologi dan seni melalui pendidikan, penelitian dan pengabdian masyarakat sesuai perundang-undangan pendidikan nasional. Namun pada kenyataanya masih banyak dosen sebagai tenaga pendidik profesional itu tidak melakukan tridarma sesuai peraturan perundang-undangan tersebut. Dalam mengukur kinerja setiap dosen supaya sesuai dengan yang disyaratkan tersebut maka perlu suatu metode bahwa dosen yang bersangkutan termasuk pada kriteria dosen baik atau kurang baik. Dalam mengetahui permasalahan diatas penelitian ini bertujuan bagaimana mengukur kinerja dosen menggunakan aplikasi sistem pendukung keputusan atau support system untuk menentukan kriteria dosen terbaik menggunakan metode Simple Additive Weighting (SAW) dalam impelementasinya sistem pendukung keputusan menggunakan server Localhost Xampp dan Database MySql. Dengan sistem pendukung keputusan ini diharapkan dapat membantu manajemen perguruan tinggi dalam menentukan kinerja dosen.
DYNAMICS OF MORBIDITY AND MORTALITY FROM MALIGNANT TUMORS IN RUSSIA
Authors: Zaridze David , Kaprin Andrey , Stilidi Ivan
Published: November 2020

The article presents an analysis of the dynamics of the incidence of malignant tumors (MT) and mortality from them. An attempt has been made to analyze the causes of the growth or decrease in morbidity and mortality from some forms of MT. Based on the analysis of domestic and international experience suggestions on planning measures to further reduce MT mortality and morbidity in the Russian Federation were made. Mortality from MT in Russia reduces mainly by decreasing of mortality from lung cancer and other forms of cancer, the cause of which is smoking, as well as from stomach cancer. Primary prevention plays a dominant role in this decline. Reducing death rates from MT alone saved the lives of at least 300 000 Russians as well as many tens of thousands of citizens of other countries of the former USSR, in which the mortality from this disease also decreased. The observed increase in MT incidence is the result of an increase in the prevalence in the population of risk factors for a number of MT. However an important role in this growth is played by the use for early diagnosis of modern highly sensitive technologies that “reveal” clinically insignificant tumors that were not previously found in clinical practice. To further reduce death rates from MT it is necessary to expand the range of preventive measures. We need a program to vaccinate adolescents against human papillomavirus (HPV). The vaccinated generation will be cured of cervical cancer and this is one of the most common forms of cancer among women. In the next 2-3 decades it is necessary to conduct regular organized screening to detect HPV infection. A serious revision of our position on screening will allow reducing mortality from cancer of the cervix, colon and rectum and, possibly, the breast. It is necessary to introduce methods of so-called drug prevention. A convincing evidences of the effectiveness of taking aspirin for the prevention of colon and stomach cancer, tamoxifen - for the prevention of breast cancer. The future of early diagnosis is of tumor markers. It is necessary to test in the population the effectiveness of determining tumor markers, for example, circulating free tumor DNA and mRNA for early detection of cancer. Of course this does not mean that we must give up measures aimed at limiting smoking and promoting healthy lifestyles. Reducing alcohol consumption, changing the type of food to reduce consumption of processed meat products and meat and increasing consumption of fish, vegetables and fruits as well as increasing physical activity will undoubtedly lead to a reduction in morbidity and mortality from many basic forms of MT.
MELATONIN AND METFORMIN IN NEOADJUVANT HORMONOTHERAPY IN LOCALLY ADVANCED BREAST CANCER
Authors: Semiglazova Tatyana , Tsyrlina Yevgeniya , Poltoratskiy Artem , Busko Yekaterina , Semiglazov Vladislav , Artemeva Anna , Ivanov Sergey , Bershteyn Lev , Anisimov Vladimir , Belyaev Aleksey , Semiglazov Vladimir , Kostorov V. , Novik Aleksey , Kasparov Boris , Osipov Mikhail , Krivorotko Petr , Klimenko Veronika , Dashyan Garik , Paltuev Ruslan , Zhiltsova Yelena , Tabagua Tengiz , Komyakhov Aleksandr , Nikolaev Kirill , Bashlyk Viktoriya , Donskikh Roman , Apollonova V.
Published: November 2020

Materials and methods. The effect of melatonin (MLT) and metformin (MTF) on the efficacy of neoadjuvant hormone therapy with toremifene was investigated in 54 patients with estrogen receptor-positive, locally advanced breast cancer (ER + BC). The average age of women was 67 years. The patients had no diabetes mellitus. The first group of patients (n = 19) received toremifene 120 mg per day, the second group (n = 16) - toremifene in combination with MLT 3 mg orally every night, the third group (n = 19) - toremifene in combination with MTF 850 mg twice daily. Randomization was performed - 1: 1: 1. The duration of therapy in all study groups was 4 months. After the end of treatment, all patients were undergone surgery. Further adjuvant treatment depended on the results of the postoperative pathomorphological conclusion. The primary endpoint was a decrease in the Ki-67% level (a surrogate marker for the effectiveness of hormone therapy), the secondary endpoints were the objective response, a pathological response in the tumor and lymph nodes, and the quality of life.
Results. In all patients (n = 54), the frequency of decrease Ki-67 level and the frequency of objective response were 57% and 50%, respectively. At the same time, the incidence of Ki-67% level decrease in the «toremifene» group was 42%, in the «toremifene+MLT» group - 56%, in the «toremifene+MTF» group - 74%. Multifactor analysis showed that the addition of MTF to toremifene increases the chances of reducing Ki-67 compared with control 4.2 times (RR 4.23 [95% CI 1,04417,139], p = 0.043). It is important that only in the patients of the «toremifene+MTF» group a significant correlation was found between the Ki-67 index decrease in the tumor and the BMI value above the norm (p = 0.015). A complete pathomorphological response in the tumor and lymph nodes was not achieved in any patient. The objective response in the study groups was 31.6%, 86.7% and 47.3%, respectively. The addition of MLT to hormone therapy with toremifene significantly increased the frequency of the objective response from 31.6% to 86.7% (x2 = 10.32, p = 0.001). The inclusion into neoadjuvant hormone therapy with toremifene of MLT or MTF did not reduce the quality of life of patients, while in 50% of patients in the «toremifene+MLT» group there was an improvement in sleep.
BIOLOGICAL EFFICIENCY OF THE PROTON SCANNING BEAM OF THE THERAPEUTIC COMPLEX "PROMETHEUS" OF THE A.F. TSYB MEDICAL RADIOLOGICAL RESEARCH CENTER IN STUDIES ON CELL CULTURE OF MURINE MELANOMA B-16
Authors: Beketov Yevgeniy , Lepilina Olga , Saburov Vyacheslav , Chernukha Aleksandr , Ulyanenko Liliya , Golovanova Olga , Malakhov Yegor , Arguchinskaya Nadezhda , Isaeva Yelena , Ulyanenko Stepan
Published: November 2020

The basis for the use of protons for radiation therapy tasks is a fixed conventional value of their relative biological efficiency equal to 1,1. Numerous studies have showed that RBE of proton radiation is not a constant value and depends on a number of factors. The purpose of this study was to determine RBE of a thin scanning proton beam at the center of the distributed Bragg peak in experiments on the culture of murine B-16 melanoma cells. The cell suspension was irradiated in an aqueous phantom by a horizontal proton beam from three directions (0,90 and 180°) in doses from 2 to 8 Gy. Modulation of the energy of proton radiation was 47,5÷92,0 MeV. RBE protons were determined from the clonogenic activity of the cells compared with 60Co gamma quanta. A linear-quadratic model was used to construct the dose dependencies. Obtained RBE values of proton radiation (LET 3÷8 keV/μm) differed in the big party from the generally accepted value and was at the level of 10% survival rate of 1.5. The results obtained generally coincided with data of foreign authors performed on different facilities.
VARIETY OF TUMOR MODELS FOR TESTING ANTITUM TREATMENT ACTIVITY OF SUBSTANCES IN MICE
Authors: Nekhaeva Tatyana , Chernov A. , Toropova Yana , Galagudza Mikhail , Baldueva Irina
Published: November 2020

Selection of tolerated and toxic doses, schemes of therapy for new anticancer drugs, assessment of its toxicity, pharmacokinetics, metabolism, study of the mechanism of action and tumor sensitivity are carried out using models of human tumors in mice. The review contains a diverse description of experimental models (transplantable, genetically engineered, humanized, autochthonous, orthotopic, heterotopic and metastatic) tumors using laboratory mice. The advantages, disadvantages, directions and specific features of the use of mouse models, their role in the study of mechanisms of action of antitumor drugs are considered on the examples of recent research.
Antibacterial Activity of Modified Carbon Sorbents, Prospective for Application
Authors: Dolgikh V. T. , Pyanova L. G. , Naumkina E. V. , Lavrenov A. V. , Matushchenko E. V. , Kornienko N. V.
Published: November 2020

The aim of the work is to study the antibacterial and antimycotic properties of carbon sorbents modified with biologically active substances in relation to pathogens of purulent-inflammatory diseases. Material and methods. The activity of modifier solutions and modified samples of carbon sorbents was studied in relation to test strains of opportunistic microorganisms in comparison with the initial sample of carbon sorbent. A suspension with a known content of microbial cells was prepared from test strains of microorganisms; it was incubated in wells with test samples for 48 hours. The survival of microorganisms was determined by quantitative inoculation from each well of the sample and microorganism mixture at regular intervals of incubation on Petri dishes with simple agar nutrient, then the number of viable microbial cells in the test mixture was counted. Results. Studies have shown high antibacterial and antimycotic activity of modified carbon sorbents. The best result in comparison with the initial sample was demonstrated by a carbon sorbent modified with lactic acid oligomers and immobilized lysozyme. Studies have shown the promise of using modified carbon sorbent samples for the application therapy in bacterial infections.
Reactive Arthritis: Modern Aspects of Diagnosis and Treatment
Authors: Belov B. S. , Balabanova R. M.
Published: November 2020

Currently, the problem of reactive arthritis (ReA) retains its importance due to the fairly high prevalence of the disease, primarily in Russia. Analysis of epidemiological data allows us to put forward a number of possible reasons explaining the different frequency of ReA in certain regions of the Russian Federation and in other countries. The lecture describes the clinical picture of the disease, as well as analyzes the significance of various laboratory techniques aimed at identifying the causative agent of ReA. The Russian diagnostic criteria for ReA are presented. The main approaches to the therapy of ReA are outlined with an emphasis on the use of antimicrobial drugs. The effectiveness and safety of drug immunocorrection (inducers of interferon, polyoxidonium, immunofan, etc.) in the treatment of urogenital chlamydia in patients with ReA have not been confirmed by data from randomized controlled trials.
«"Dels ·XII· signes del cel e de la natura de cascuns". Edició crítica d’un fragment de la traducció catalana medieval del Breviari d’amor de Matfre Ermengaud»
Authors: Capdevila Arrizabalaga Irene
Published: November 2020

Resum: En aquest treball es presenta l’edició inèdita del fragment dedicat als dotze signes del zodíac de la traducció catalana medieval de l’obra didàctico-enciclopèdica Breviari d’amor de Matfre Ermengaud.Paraules clau: Matfre Ermengaud, Breviari d’amor, traducció catalana medieval, signes del zodíac, literatura didàctico-enciclopèdica.«"Dels ·xii· signes del cel e de la natura de cascuns". Critical edition of a fragment of the Catalan medieval translation of Matfre Ermengaud’s Breviari d’Amor»Abstract: This article presents the unpublished edition of the section devoted to the twelve signs of the Zodiac in the Catalan medieval translation of the didactic and encyclopaedic work Breviari d’amor of Matfre Ermengaud.Keywords: Matfre Ermengaud, Breviari d’amor, Catalan Medieval translation, Signs of the Zodiac, Didactic and Encyclopaedic Literature.
«Técnica e inspiración en la poesía de Ferrán Manuel de Lando»
Authors: Álvarez Ledo Sandra
Published: November 2020

Resumen: Este artículo se encamina a analizar el tratamiento de la métrica en las composiciones conservadas de Ferrán Manuel de Lando para valorar el relieve de los aspectos técnicos en la obra del autor, quien desdeñó la importancia de las normas del arte de trovar frente a la inspiración y recibió duras críticas de impericia por parte de otros poetas. Con este fin, se analiza la estructura estrófica de los textos, los procedimientos para la elaboración de versos y rimas, así como el empleo de determinadas estrategias para el embellecimiento métrico de las composiciones. La consideración de estos elementos se lleva a cabo atendiendo al contexto literario en que Lando desarrolló su labor y, también, reflexionando sobre los efectos que el proceso transmisor pudo ejercer sobre el nivel formal de las piezas conservadas.Palabras clave: Lando, métrica, estrofas, versificación, rimas, estrategias retóricas.«Technique and inspiration in Ferrán Manuel de Lando’s poetry»Abstract: The main purpose of this article is to analize the metrical uses in Ferrán Manuel de Lando’s known poems in order to arrive into conclusions about the relevance that this formal component had in the author’s poetry, who disdained the importance of the poetic rules against inspiration and received harsh criticism from other poets. According to this, it analizes the stanzas structure, versification, rimes, as well as the use of specific strategies for the metrical enrichment. The matter is taken by considering the literary context in which Lando developed his work and reflecting on the effects that the transmission process could have caused over the conserved poems’ formal level.Keywords: Lando, Metrics, Stanzas, Versification, Rimes, Rethorical Strategies.
«Debates en torno al ocio en la narrativa anglonormanda: del Brut de Wace al Roman de Horn e Ipomedon»
Authors: Dumas María
Published: November 2020

Resumen: El trabajo analiza la recepción del problema planteado por el ocio, la recreantise, en la narrativa caballeresca de la Inglaterra anglonormanda. Esta cuestión, introducida por Wace en el Brut, fue abordada de manera célebre por Chrétien de Troyes en su primer roman, Erec et Enide. Sin embargo, como se desprende de la lectura del Roman de Horn de Thomas y de Ipomedon de Hue de Rotelande, en el ámbito insular este debate también goza de gran vitalidad, aunque recibirá un tratamiento diferente. La representación de un héroe ocioso lleva tanto a Thomas como a Hue a problematizar, por distintas vías, las convenciones narrativas propuestas por el roman como género. La resistencia manifestada por ambos autores hacia este modelo genérico será determinante en el desarrollo ulterior del género, tanto en dialecto anglonormando como en inglés medio, y constituye un testimonio de gran valor sobre las peculiaridades de la recepción del roman en la Inglaterra del siglo XII.Palabras clave: roman anglonormando, ocio, Roman de Horn, Ipomedon.«Discussing idleness in Anglo-Norman narrative: from Wace’s Brut to the Roman de Horn and Ipomedon»Abstract: The aim of this article is to analyze how the problem of idleness, i.e. recreantise, is addressed in Anglo-Norman chivalric literature. This question, introduced by Wace in his Brut, was notably handled by Chrétien de Troyes in his first romance, Erec et Enide. However, as it becomes evident from Thomas’s Roman de Horn and Hue de Rotelande’s Ipomedon, this discussion was also quite lively in the insular context. Representing an idle hero leads both Thomas and Hue to challenge, in different ways, the narrative conventions of the romance genre. The resistance evinced by the two authors towards this generic model would be highly influential on the later development of the genre in England, both in Anglo-Norman and Middle English, and affords a valuable testimony to the peculiarities of the reception of romance in twelfth-century England.Keywords: Anglo-Norman romance, idleness, Roman de Horn, Ipomedon.
«Perigos e medos nas Cantigas de Santa Maria. Do mar e dos seus tormentos»
Authors: González Déborah
Published: November 2020

Resumo: Nas Cantigas de Santa Maria de Alfonso X, a sociedade medieval aparece representada dun modo máis ou menos realista. Textos e imaxes dan conta da mobilidade característica dos distintos grupos sociais que aparecen retratados nesta colección. Ademais, estas viaxes adoitan presentarse en estreita relación ao marabilloso, de tal modo que se presentan como unha aventura transformadora, non exenta de risco e emocións. Este traballo céntrase naquelas narracións das Cantigas de Santa Maria que incorporan unha travesía por mar, que normalmente aparece descrito como un medio indómito e perigoso para os homes, atendendo ás emocións que se desencadenan neses episodios de perigo mariño.Palabras chave: Cantigas de Santa Maria, Lírica galego-portuguesa, emocións, medo, coita, perigos do mar.«Danger and fear in the Cantigas de Santa Maria. Do mar e dos seus tormentos»Abstract: In the Cantigas de Santa Maria of Alfonso X, the medieval society is represented in a realistic manner. Into the collection, texts and images show the movement of different social groups. In addition, their travels involved marvels and miracles, so they were transforming adventures with risks and emotions. This paper aims to explore some narratives of the Cantigas de Santa Maria that include a journey across the sea, which is usually described as a wild and unsafe environment for medieval people, paying attention to the emotions that are triggered in those episodes of danger.Keywords: Cantigas de Santa Maria, Galician-Portuguese lyric, emotions, fear, coita (anxiety), dangers of the sea.
«A vueltas con la progresión narrativa en la lírica gallego-portuguesa. ¿Una secuencia en las Cantigas de Sancho Sanchez, clérigo?»
Authors: Pousada Cruz Miguel Ángel
Published: November 2020

Resumen: Los apógrafos renacentistas B y V conservan un conjunto de cinco cantigas de amigo y una cantiga de amor que son atribuidas, a la luz de las rúbricas atributivas y de la Tavola colocciana, al clérigo Sancho Sanchez. En este trabajo se analiza la posible existencia de una secuencia narrativa entre esas seis composiciones, tras una lectura y un atento análisis de los textos.Palabras clave: Sancho Sanchez, clérigo, secuencia narrativa, secuencia lírica, progresión narrativa, lírica profana gallego-portuguesa.«Rethinking the narrative progression in Galician-Portuguese lyric poetry. Is there a sequence in the cantigas by Sancho Sanchez, clérigo?»Abstract: The Renaissance apographs B and V preserve a collection of five cantigas de amigo and a cantiga de amor attributed to the clergyman Sancho Sanchez, in the light of the identifying rubrics and the tavola by Colocci. The aim of this paper is to analyze the possible existence of a narrative sequence among the aforementioned six verses, following a detailed reading and examination of the poems.Keywords: Sancho Sanchez, clérigo, narrative sequence, lyric sequence, narrative progression, Galician-Portuguese prophane lyric poetry.
«El espacio construido, el banquete y la fiesta en Durmart le Galois»
Authors: Bermejo Larrea Esperanza
Published: November 2020

Resumen: Durmart le Galois no es una novela artúrica convencional. Los caballeros de la Tabla Redonda son relegados a un segundo plano frente al protagonismo que cobra el héroe epónimo. Su estructura carece de una etapa de crisis personal o social del héroe, de forma que la aventura constituye un itinerario cuyas etapas se despliegan a través de una vasta geografía. Los castillos y ciudades se imponen sobre otros espacios salvajes, como el bosque, más frecuentes en otras obras caballerescas. La descripción de estos lugares construidos parte de los cánones establecidos por la tradición literaria, pero se aleja después y muestra un espacio amable, abierto a la sociabilidad y al entretenimiento. El ambiente festivo inunda la novela y encuentra su culminación en el banquete, con sus rituales y su protocolo. En torno a la mesa, los comensales intercambian conversaciones que mar- carán el progreso de la intriga.Palabras clave: espacio, sociabilidad, banquete, fiesta.Abstract: Durmart le Galois is not a conventional Arthurian novel. The knights of the Round Table are pushed into the background, while relevance is given to the eponymous hero. Its structure lacks a stage of personal or social crisis of the hero, so, adventure covers an itinerary whose stages are displayed throughout a vast geography. Castles and cities replace other wild spaces, such as the forest, which are more frequent in other chivalric works. The description of these built-up spaces starts from the pre-established literary canons, but later it moves away from conventions, and it depicts a gentle space, which is open to sociability and entertainment. A merry atmosphere floods the novel, and it reaches its climax in the banquet, with its rituals and protocol. Around the table, guests exchange conversa- tions, which will influence the unfolding of the plot.Keywords: space, sociability, banquet, party.
«Entre la realidad y la ficción. El ornato femenino en la literatura castellana bajomedieval y renacentista»
Authors: Hamer Flores Adolfo , Criado Vega Teresa María
Published: November 2020

Resumen: El presente trabajo analiza las técnicas de elaboración de cosméticos contenidos en obras de literatura castellana de fines del medievo y primeros momentos del Renacimiento, comparándolas con la realidad recogida en recetarios castellanos coetáneos. En dichas obras aparecen un número importante de recetas que muestran el fin de los afeites, los ingredientes usados en su elaboración y, en menor medida, el proceso o procesos seguidos en su ejecución. Todo ello pone de relieve una faceta poco estudiada de la vida cotidiana del medievo y primeros años del Renacimiento, relacionada con la estética y la belleza y con el cuidado del cuerpo.Palabras clave: canon de belleza, cosmética, literatura castellana, recetas, mujer.Abstract: This paper analyzes the techniques for preparing cosmetic contained in works of Spanish literature of the late Middle Ages and early Renaissance times, comparing with reality recipe collection in Castilian contemporaries. In such work a number of recipes to show the makeup, the ingredients used in its preparation and to a lesser extent, the process or processes used in its execution appear. All this highlights a little-studied facet of daily life in the Middle Ages and early Renaissance, related to aesthetics and beauty and body care.Keywords: canon of beauty, cosmetics, Spanish literature, recipes, woman.
«Variantes, variaciones e imprenta: SA10A y 11CG»
Authors: Rodado Ruiz Ana M.
Published: November 2020

Resumen: El ms. 2763 de la Biblioteca Universitaria de Salamanca es un códice que contiene dos cancioneros colectivos independientes. El códice consta de 163 folios y su primera parte –SA10a, según el sistema de siglas de Brian Dutton (El cancionero del siglo XV, c. 1300-1520, Salamanca, Universidad de Salamanca, 1990-91)– ocupa los folios 1-93 y contiene 75 composiciones. De ellas, solo siete llegaron a la imprenta, cuando fueron publicadas por Hernando del Castillo en el Cancionero General de 1511 (11CG). El objetivo de este artículo es analizar el proceso de transmisión de esas obras desde el manuscrito hasta su recepción en el Cancionero General, a través del recuento y estudio de las variantes textuales en el impreso y de la collatio con las que aparecen en otros testimonios manuscritos. En última instancia, este trabajo demuestra que el análisis de variantes y variaciones resulta útil para avanzar en el estudio de la génesis y transmisión de SA10a.Palabras clave: cancioneros españoles del siglo XV, variantes textuales, manuscritos e impresos.Abstract: Ms. 2763 Salamanca University Library is a codex that contains two independent collective songbooks. The codex consists of 163 folios, and its first part –SA10a, according to Brian Dutton’s acronym system (El cancionero del siglo XV, c. 1300-1520, Salamanca, Universidad de Salamanca, 1990-91)– extends from the folio 1 to 93 containing 75 compositions. Only seven of these reached to print, when were published by Hernando del Castillo in the Cancionero General (11CG). This article aims to analyze the textual transmission process of those works, from the manuscript to their reception in the Cancionero General of 1511, through the recount and examination of the printed textual variants, and the collatio with others variants appeared in manuscript testimonies. Finally, this article provides evidence that the analysis of variants and variations is helpful to further research on the study of the genesis and transmission of SA10a.Keywords: Fifteenth Century Spanish Songbooks, textual variants, manuscripts and printing.
«El recetario final del manuscrito BNE 3378. Edición crítica»
Authors: Pensado Figueras Jesús
Published: November 2020

Resumen: El estudio de las obras científicas en lengua vulgar no ha dejado de intensificarse en los últimos años y de realizar aportaciones significativas en los ámbitos de la lexicografía diacrónica y de la historia de la medicina. Asimismo, al tratarse generalmente de versiones de textos latinos, las obras en romance aportan elementos de estudio para la historia de la traducción, así como para la circulación y difusión de los textos científicos por la geo- grafía europea. El presente trabajo añade una nueva obra a este elenco, con el análisis y la edición crítica del recetario anónimo, inédito hasta ahora, que se encuentra en los folios finales del manuscrito 3338 de la Biblioteca Nacional de España.Palabras clave: Recetario, Macer Floridus, Thesaurus Pauperum, medicina medieval.Abstract: Studies about scientific works in vulgar tongue have not stopped increasing in the last years and making significant contributions in the fields of diachronic lexicography and the history of medicine. Likewise, as they are usually versions from Latin texts, the works in Romance provide elements of study for the history of translation and also for the circulation and spreading of scientific texts all over Europe. The present work adds a new study to this huge catalogue with the analysis and critical edition of the anonymous receptary, unpublished up to now, mentioned in the last folios of manuscript mss. 3338 of the National Library of Madrid.Keywords: Receptary, Macer Floridus, Thesaurus Pauperum, Medieval medicine.
«Female (co)authorship in Cancionero Poetry»
Authors: Gómez-Bravo Ana M.
Published: November 2020

Resumen: La autoría femenina era una cuestión polémica en la Iberia del siglo XV y principios del XVI. Gran parte de la producción poética de este período estaba asociada con la interacción social, lo que permitía una compleja negociación de la autoría y los papeles de género. Si bien el discurso femenino era fundamental para la escritura poética y las prácticas culturales relacionadas con el mismo, estaban en funcionamiento prácticas editoriales que suprimían las contribuciones de las mujeres a la escritura. El estudio apunta a una imbricación textual del discurso femenino y masculino en varias etapas de la composición poética y propone una reconsideración de las aproximaciones a la autoría femenina (y masculina).Palabras clave: Cancionero, mujeres escritoras, poesía medieval, poesía renacentista.Abstract: Female authorship was a contentious subject in fifteenth- and early sixteen-century Iberia. During the period, a substantial amount of poetic production was associated with social interaction, which enabled a complex negotiation of authorship and gender roles. While female discourse was central to poetic writing and to the cultural practices connected to it, editorial practices worked to erase women’s contributions to poetic writing. The study shows a textual imbrication of female and male discourse at several stages of poetic composition and proposes a reconsideration of existing approaches to female (and male) authorship.Keywords: Cancionero, Women writers, medieval poetry, renaissance poetry.
«El tono proverbial del Cantar de mio Cid»
Authors: Justel Pablo
Published: November 2020

Resumen: En el presente trabajo se examinan cinco ejemplos de «pseudo- rrefranes» del Cantar de mio Cid, compuestos por una prótasis (introducida por el relativo indefinido «qui») y una apódosis. Se verá cómo estos cinco casos poseen implicaciones en la caracterización de los personajes, el didactismo del poema y su estructura.Palabras clave: Cantar de mio Cid, refranes, proverbios, estética, estructura.Abstract: The present study examines five examples of «pseudoproverbs» from the Cantar de mio Cid, composed of a protasis (introduced by the indefinite pronoun «qui») and an apodosis. This examination will highlight the implications these examples have on the didacticism of the poem and its structure as well as the portrayal of the characters.Keywords: Poem of my Cid, sayings, proverbs, aesthetics, structure.