bluuebunny/crossref_metadata_2025 huggingface dataset:
Counterintelligence and the Changing Threat Landscape
Authors: Stanton Daniel
Published: June 2023

On March 16, 2023, Daniel Stanton—Director, National Security Program, University of Ottawa, Professional Development Institute—presented Counterintelligence and the Changing Threat Landscape.  The presentation was followed by a question-and-answer period with questions from the audience and CASIS Vancouver executives. The key points discussed were the definitions and outcomes of offensive and defensive counterintelligence (CI), the principle states engaged in CI, and the shift in CI tactics and operations in recent years.
Received: 2023-05-14
Revised: 2023-05-25
Herwaardering van Grotius’ De satisfactione
Authors: Hoogenboom R.P.
Published: June 2023

Grotius refuted Socinus’ attack on the Reformed theory of satisfaction in his De satisfaction, which contains a translation of the doctrine of satisfaction into a legal framework, but it was not understood by everyone. On its surface and within the broader context of De satisfactione, Grotius’ statements about punishment demanded by the common good and the relaxatio of the law, have been misinterpreted to say that Grotius deviated from the orthodox theory of satisfaction. A close analysis of De satisfactione, however, shows that Grotius is closely aligned with Reformed doctrine of satisfaction. As an Arminian Grotius only deviates from the later formulated Canons of Dort about the extent of the atonement.
METAPHYSICS OF THE OBJECT-IMAGE DICHOTOMY IN ARCHITECTURE
Authors: Tkachev Valentin
Published: June 2023

The physical and mental development of the phenomena of the world presupposes the distinction between the ob-ject of knowledge and the concept of it.
The discovery of the difference between a thing and the idea of a thing became an unprecedented triumph of sci-ence in ancient Greece, noted Soviet art critic A. F. Losev [1].
The «stratification» of the object of study marked the beginning of a centuries-old confrontation between ideal-ism and materialism. The thesis «the idea of a thing exists by itself» has been overcome by progressive science for a long time, but recently it has risen from the ashes by the efforts of philosophers of the XX century, who declared the priority of thinking as a creative tool for replacing reality with hyperreality, the triumph of imagination over reality – and quite reasonably.
The concept of metaphysics («that which is after – or outside–physics») is addressed precisely to the idea of a thing that precedes and closes the process of perception of the object of cognition with a conditional shell of a meta-physical cloud that provides functional and aesthetic persuasiveness in this case of architectural work in the role of a synharmonic superstructure, artistic comprehension superimposed on a physical medium – a conceived or realized object.
Vitruvius also considered the content of architecture as a unity of thought and practice [2]. Not to the detriment of the sacred triad «benefit–strength–beauty», the article proposes to consider the dichotomy «architectural object–its semantic image», the dynamics of its historical unfolding.
LOGICAL METHODS OF FORECASTING ENVIRONMENTALLY SAFE HANDLING OF TECHNOSPHERE OBJECTS
Authors: Tshovrebov Eduard
Published: June 2023

The relevance of research in the field of environmental protection, ensuring the environmental safety of the life support of settlements, incl. construction and urban economy, as well as energy and resource saving, rational, eco-nomical, careful use of natural resources is predetermined by the modern course of the Russian state and society to-wards sustainable socio-economic development. The purpose of this study was the formation of necessary and suffi-cient conditions, predictive parameters and indicators of the transition of the life support system of technosphere ter-ritories to a resource-saving technological mode of environmentally safe life. To achieve this goal, for the first time the methods of logical and mathematical analysis were applied, which, according to the author's intention, implement the function of transition from the managerial and organizational and technical formulation of the problem to its mathematical formalization. The paper uses a new conceptual author's approach to the identification of technosphere objects not as sources of environmental and sanitary hazard, but as resource and raw material components of the re-production of material goods, taking into account the implementation of the strategic tasks of preserving the non-renewable strategic reserve of natural resources of the Russian Federation, protecting the population, components of natural environment and territories from unfavorable technospheric factors and environmental threats, possible emergency situations of a man-caused nature. Based on the results of the research, the paper solves the problem of logical analysis and forecasting of the parameters of environmentally safe life on the basis of resource-saving princi-ples of re-use of construction and other products that have completed their service life, were in use. The results of the work can be used in the formation of strategies, concepts, programs for sustainable socio-economic, environmental, industrial-technological, scientific and technical development of various sectors of the economy, municipalities and regions based on the transition to a resource-saving technological mode of environmentally safe life support for terri-tories.
Acquisition of a Lexicon for Family History Information: Bidirectional Encoder Representations From Transformers–Assisted Sublanguage Analysis
Authors: Wang Liwei , He Huan , Wen Andrew , Moon Sungrim , Fu Sunyang , Peterson Kevin J , Ai Xuguang , Liu Sijia , Kavuluru Ramakanth , Liu Hongfang
Published: June 2023

Background

A patient’s family history (FH) information significantly influences downstream clinical care. Despite this importance, there is no standardized method to capture FH information in electronic health records and a substantial portion of FH information is frequently embedded in clinical notes. This renders FH information difficult to use in downstream data analytics or clinical decision support applications. To address this issue, a natural language processing system capable of extracting and normalizing FH information can be used.

Objective

In this study, we aimed to construct an FH lexical resource for information extraction and normalization.

Methods

We exploited a transformer-based method to construct an FH lexical resource leveraging a corpus consisting of clinical notes generated as part of primary care. The usability of the lexicon was demonstrated through the development of a rule-based FH system that extracts FH entities and relations as specified in previous FH challenges. We also experimented with a deep learning–based FH system for FH information extraction. Previous FH challenge data sets were used for evaluation.

Results

The resulting lexicon contains 33,603 lexicon entries normalized to 6408 concept unique identifiers of the Unified Medical Language System and 15,126 codes of the Systematized Nomenclature of Medicine Clinical Terms, with an average number of 5.4 variants per concept. The performance evaluation demonstrated that the rule-based FH system achieved reasonable performance. The combination of the rule-based FH system with a state-of-the-art deep learning–based FH system can improve the recall of FH information evaluated using the BioCreative/N2C2 FH challenge data set, with the F1 score varied but comparable.

Conclusions

The resulting lexicon and rule-based FH system are freely available through the Open Health Natural Language Processing GitHub.
Effect of cortisol on achieving target blood pressure levels in patients with resistant hypertension and chronic kidney disease
Authors: Sirenko Yu.M. , Rekovets O.L.
Published: June 2023

Background. Resistant hypertension is defined as failure to achieve the target blood pressure (BP), despite treatment with at least three antihypertensive drugs that include a diuretic, and is associated with a poor prognosis. This is caused by organ damage from long-term exposure to high blood pressure, and is also linked to diabetes mellitus, chronic kidney disease and obesity. The purpose of the work is to evaluate biological markers associated with failure to achieve the target level of blood pressure in patients taking 3 or more antihypertensive drugs, depending on the presence of chronic kidney disease. Materials and methods. The study included 1146 patients with resistant hypertension who took 3 or more antihypertensive drugs. They were examined using both instrumental and laboratory methods with the measurement of office blood pressure upon admission to the hospital and upon discharge, evaluation of biochemical blood parameters, levels of creatinine, blood lipids, renin, blood aldosterone, cortisol. Results. The average age of the patients was 57.90±0.37 years. There were more women than men— 62.7 versus 36.7%. The body mass index was 31.00±0.19kg/m2. The average office systolic/diastolic BP upon admission to the hospital was 174.60±0.64/100.50±0.38 mmHg. 22.4% of patients had glomerular filtration rate (GFR) <60ml/min/1.73m2. In the subgroup with GFR ≥60ml/min/1.73m2, the achievement of the target BP was 44.76%, which is significantly higher than in patients with GFR <60ml/min/1.73m2 (12.56%, p<0.05). Blood cortisol level in the subgroups with failure to reach the target level of office blood pressure was 127.72±4.20 μg/dl (with GFR<60 ml/min/1.73m2) and 163.71±15.20 μg/dl (GFR ≥60ml/min/1.73m2), which was significantly higher compared to the patients with the target BP level: 6.02±0.90 μg/dl (with GFR <60ml/min/1.73m2; p<0.05) and 47.84±4.40 μg/dl (in the subgroup with GFR ≥60ml/min/1.73m2; p<0.05). Conclusions. In patients with resistant hypertension, elevated blood cortisol content, regardless of GFR, was associated with failure to achieve the target level of office blood pressure.
The influence of nanodispersed cerium oxide on the development of oxidative stress and the production of nitric oxide in patients with type 2 diabetes mellitus
Authors: Shayenko Z.O. , Akimov O.E. , Neporada K.S. , Ligonenko O.V. , Spivak M.Ya.
Published: June 2023

Background. In the pathogenesis of complications of diabetes mellitus (DM), in addition to glucotoxicity, the development of oxidative stress plays a leading role. Antioxidants have been of great interest for physicians in recent years. Contemporary diabetology have been focused on the search and practical implementation of pathogenetic medications that can affect the main chains of DM and prevent its negative consequences. Purpose of the study is to determine the effect of nanodispersed cerium oxide (NCO) on the production of nitric oxide (NO), the activity of antioxidant enzymes and the intensity of lipid peroxidation in the blood of patients with type 2 diabetes mellitus. Materials and methods. Seventy-two patients aged 36 to 66 years, average age of 55.20±6.82 years, who received treatment at the Municipal Clinical Hospital 2 in Poltava from July to December 2022 have been involved in the study. They have been divided into 2 groups: controls (n=35), which included people without diabetes; experimental group (n=37), which consisted of patients diagnosed with type 2 DM. Results. The use of NCO in patients with type 2 DM significantly reduces the activity of inducible NO synthase in the blood by 34.70% and the activity of arginases by 52.17% compared to the levels before treatment. The use of nanodispersed cerium oxide in the treatment of type 2 DM increases the activity of superoxide dismutase in the blood by 102.74%, and the activity of catalase by 103.04% compared to same indicators in the experimental group before therapy. Notably, blood malondialdehyde was significantly lower (by 2.35 times) compared to the same indicator before treatment. Conclusions. The use of NCO in patients with type 2 diabetes mellitus leads to an increase in antioxidant protection and a decrease in the intensity of lipid peroxidation in blood. NCO reduces the production of nitric oxide from the inducible NO synthase and weakens the competition between NO synthases and arginases for the reaction substrate. The findings of the study justify the need to include antioxidants in the pathogenetic therapy of diabetes mellitus and its complications.
The effect of the combined use of myo-inositol, vitaminD and selenium on the cytokine status in women of reproductive age with autoimmune thyroiditis
Authors: Pasyechko N.V. , Kulchinska V.M.
Published: June 2023

Background. In recent years, in Ukraine and other countries of the world, there has been an increase in the frequency of autoimmune thyropathies. A significant role in the pathogenesis of autoimmune thyroiditis (AIT) is played by cytokines whose production is increased significantly during immunopathological reactions. The purpose of study was to investigate the effect of the combined use of myo-inositol, vitamin D and selenium on the cytokine status of women with euthyroidism, subclinical hypothyroidism and overt hypothyroidism against the background of autoimmune thyroiditis. Materials and methods. One hundred and forty-seven women aged 18–43 with AIT and 30women of the control group were under observation. Patients of first group (n = 74) received myo-inositol at a dose of 2000 mg/day, cholecalciferol 2000 IU/day, and selenium 100 μg/day additionally to the main treatment. Patients of the second group (n = 73) received only cholecalciferol at a dose of 2000 IU/day and selenium 100μg/day additionally to the main treatment. The functional state of the thyroid gland was studied by determining the levels of thyroid-stimulating hormone, free thyroxine, free triiodothyronine, antibodies to thyroid peroxidase (Ab-TPO) and antibodies to thyroglobulin (Ab-TG). The state of the systemic and local inflammatory process was evaluated according to parameters of tumor necrosis factor α, interleukins 6, 10, 17, and 23. Results. It should be noted all patients with AIT had changes in cytokine status, with some differences depending on the clinical variant of autoimmune thyroid disease. After three months of treatment of patients of the first group with myo-inositol at a dose of 2000 mg/day, cholecalciferol 2000 IU/day and selenium 100 μg/day, and patients of the second group only with cholecalciferol at a dose of 2000 IU/day and selenium at 100 μg /day, a significant difference was found between the indicators in both studied cohorts. Conclusions. The administration of myo-inositol, vitamin D, and selenium had a combination effect on the reduction of cytokine indicators, Ab-TPO and Ab-TG levels, which contributed to the compensation of the underlying disease.
Bempedoic acid: mechanism of action and therapeutic use in atherosclerotic cardiovascular diseases and diabetes
Authors: Serhiyenko V.A. , Serhiyenko A.A.
Published: June 2023

Bempedoic acid is a new cholesterol-lowering drug that recently received approval from the US Food and Drug Administration and the European Medicines Agency. This drug targets lipid and glucose metabolism as well as inflammation by downregulating the ATP citrate lyase and upregulating of AMP-activated protein kinase (AMPK). The main effect is to reduce cholesterol synthesis in the liver, and its use is generally not associated with undesirable muscle disorders. Bempedoic acid can reduce the processes of gluconeogenesis, which leads to an improvement in insulin sensitivity, glucose metabolism and features of the metabolic syndrome. The anti-inflammatory effect of bempedoic acid is mainly achieved by activating the AMPK pathway in immune cells, which helps reduce the level of C-reactive protein in plasma. The effects of bempedoic acid on the course of atherosclerotic cardiovascular disease, type2 diabetes and chronic liver disease have been evaluated in randomized clinical trials that require further research. Phase III clinical safety trial show that bempedoic acid is generally well tolerated in combination with statins, ezetimibe, or proprotein convertase subtilisin/kexin type 9 inhibitors in achieving target levels of low-density lipoprotein cholesterol. The aim of this review is to analyze the main mechanisms of action, potential clinical targets of bempedoic acid and describe the existing evidence from clinical trials. The search was done in the Scopus, Science Direct (from Elsevier), and PubMed databases, including the Medline. The following keywords were used: bempedoic acid, low-density lipoprotein cholesterol, atherosclerotic cardiovascular diseases, diabetes. In order to identify research results that could not be found during the online search, a manual search of the bibliography of publications was used.
Klinefelter syndrome in combination with familial male-limited precocious puberty (clinical case)
Authors: Sorokman T.V. , Koliesnik D.I. , Cherney N.Ya.
Published: June 2023

The article presents the results of a literature review on Klinefelter syndrome combined with familial male-limited precocious puberty and describes a clinical case. Klinefelter syndrome is a form of male hypogonadism, characterized by the presence of an extra X chromosome, small testes, seminiferous tubule dysgenesis, high levels of gonadotropin, low serum testosterone level, underdeveloped secondary sex characteristics and male infertility. Klinefelter syndrome is characterized by extreme heterogeneity of clinical and genetic manifestations. The prevalence of Klinefelter syndrome is 0.1 to 0.2% in male newborns and increases to 3 to 4% among infertile men and 10 to 12% in patients with azoospermia. Currently, it is not known how to treat patients with mild Klinefelter syndrome that remains undiagnosed or is combined with other genetic pathology, including gonadotropin-independent precocious puberty. This disease is caused by an autosomal dominant inherited activating pathogenic variant of the gene encoding the luteinizing hormone/chorionic gonadotropin receptor, which belongs to the family of G protein-coupled receptors. In men, activation of pathogenic variants of this gene causes excessive secretion of testosterone, which triggers early peripheral (precocious) puberty. Treatment recommendations have been developed in part mainly because of the limited number of reported cases, small sample sizes, and short-term outcomes. The presented clinical case is important in view of the possible risk of developing malignant testicular neoplasms in patients with precocious puberty. Therefore, long-term follow-up during and after puberty is recommended. It is of great importance to take into account the aforementioned clinical manifestations in order to made early diagnosis of this syndrome, offer timely genetic counseling to parents, and rehabilitate these patients physically, psychically and socially.
The Language of social media: A Structuralist Inquiry
Authors: S. Revathy
Published: June 2023

Kevin Kelly, a futurist, puts forth the idea of a seventh kingdom to add to the six-kingdom classification. He labels this kingdom as the “technium.” It refers to all things invented by humans and includes, but is certainly not limited to, such phenomena as the Internet (Lobo, 2017). The language that has developed as a result of the emergence of some phenomena of the technium (for instance, social media) is now integrating into, and sending shockwaves through human languages, especially English. The latter of the two languages is one with a long history of change and unfailing adaptation. As such, the steady burgeoning of this unhackneyed technological vocabulary may not hold serious consequences for the English language which, as it has done numerous times before, will reorient itself around the insurgence of new words and abbreviations. However, for the first time in centuries (taking into consideration the cave paintings of old), there is an alarming increase in the substitution of words and phrases by visual equivalents, all of which seek to literalize the adage that a picture can speak a thousand words. This hybrid language however is still just that — a language, a system of signs as Swiss linguist Ferdinand de Saussure put it. This paper seeks to conduct an analysis of this fairly new language using the methodology of structuralism, employing various theories put forth by critics associated with this umbrella term. Such an analysis would be directed towards facilitating an understanding of this new technological language in its various manifestations.
Niger Delta Literature: Emerging Thematic Preoccupations in Nigerian Literature
Authors: Davies Rebecca Ufuoma
Published: June 2023

The Nigeria Delta region has long been a hotbed of literary activity, producing writers of international repute such as Tanure Ojaide, Chris Aban and Ken Saro-Wiwa. However, in recent years, there has been an emergence of new voices from the region, which is bringing to the fore new thematic preoccupations that reflect the changing socio-political realities of the region. Thus, the paper provides an overview of the emerging thematic preoccupations in Nigeria Delta literature, drawing from a range of contemporary literary works from the region. The paper identifies three key themes that are increasingly becoming central to the discourse of Nigeria Delta literature: environmental degradation, political corruption, and youth restiveness. The first theme, environmental degradation, reflects the devastating impact of oil exploration and exploitation on the Niger Delta region. The second theme, political corruption, is a recurring motif in Nigeria Delta literature. The third theme, youth restiveness, reflects the increasing frustration and anger of young people in the Niger Delta region. Overall, this paper argues that the emerging thematic preoccupations in Nigeria Delta literature reflect the changing socio-political realities of the region. By engaging with these themes, Nigeria Delta writers are providing powerful critiques of the problems facing the region, as well as offering new visions for a more just and equitable future.
Health Consciousness of School Going Adolescents*
Authors: George Anu
Published: June 2023

The study was conducted among the school going adolescents in Kerala to assess their socio-personal profile, food consumption pattern and to understand their health consciousness and health status through health indicators like Body Mass Index (BMI). The study revealed that 15.6 per cent of the respondents had symptoms suggestive of some nutritional problems. Regarding BMI, above two-third of the students were included in the underweight category, 1.7 per cent were having overweight and a small percentage were even obese.
Comparison of Bacterial Pathogens Causing Urinary Tract Infection among Catheterized and Non-catheterized Patients at a Tertiary Care Hospital, Jamnagar
Authors: Fefar Disha Rameshbhai , Shingala Hitesh Kantilal , Mehta Krunal Dineshbhai , Shah Ruchi Virendrakumar
Published: June 2023

Urinary tract infections (UTIs) are among the most common bacterial infections of the urinary tract, accounting for a high percentage of all infections. The insertion of a catheter into the bladder increases the susceptibility of the patient to tract infection and serves as the initial site of infection by introducing pathogenic organisms into the tract. Indwelling catheters in the bladder facilitate the colonization of uropathogens through various mechanisms. The objective of this study was to compare the different pathogenic bacteria causing UTIs and their antibiotic sensitivity patterns in catheterized and non-catheterized patients. The study included catheterized and non-catheterized patients, regardless of gender, exhibiting clinical signs or symptoms of urinary tract infection. Urine samples were examined and cultured for bacterial growth using standard microbiological procedures. After confirming the pathogens, antibiotic susceptibility testing was conducted on Mueller-Hinton agar using the Kirby-Bauer disc diffusion method. Out of the 200 samples, 88 were catheterized and 112 were non-catheterized. Catheterized patients exhibited a higher infection rate (39, 44.32%) compared to non-catheterized patients (31, 27.68%), and women had a higher infection rate than men. Various organisms were isolated, with Escherichia coli being the most common organism in both catheterized and non-catheterized patients. Among the tested drugs against gram-negative organisms, nitrofurantoin displayed higher sensitivity. The present study demonstrated a higher incidence of bacterial infection in catheterized patients compared to non-catheterized patients, highlighting the importance of avoiding unnecessary catheter insertion. To prevent antimicrobial resistance, it is crucial to implement various infection control policies, care bundle approaches, and regular surveillance.
Enterococcus Species: A Systemic Review
Authors: Kalode Vaishnavi , Patil Praful
Published: June 2023

Enterococci are gram-positive facultative anaerobes, these are commensals in the intestinal system of numerous animals, including humans. They affect hospitalized patients and cause nosocomial infections, respiratory infections, endocarditis, wound infections, UTIs, and other enterococcal infections. This discovery can be explained by hemolysin, gelatinase, aggregation substances, hyaluronidase, capsular polysaccharides, and cell wall carbohydrate. Various enterococcal spp. include Enterococcus avium Vancomycin resistance was acquired by enterococci throughout the antibacterial spectrum, primary antibiotic used regimen based on dual β lactams and aminoglycosides.
Document Analyzing Using Deep Learning
Authors: Akare Prajwal
Published: June 2023

Abstract: Many businesses and large organizations have a large set of documents that need to be stored in various locations. cluster. In recent years, this task has become time consuming as the number of documents and articles has increased. Analysis of Documents are her one of the subjective research techniques analysts use to validate ideas. with some help. A visual technique that takes full advantage of layout and text formatting in a very clean output format. with the help of the model Most large and lots of architectural documents can be sorted. With the help of layout models and new interaction strategies Various layouts of any format within a single.
Plant Disease Detection and it’s Health Monitoring using CNN and Arduino
Authors: Bhargav Ganipisetty Akhil , Pathak Dr. Ajita
Published: June 2023

Abstract: Plant diseases are a major threat to crop yield and food security. Early detection and diagnosis are crucial to prevent the spread of disease and minimize crop losses. Plant diseases can have devastating effects on crop yields and food security. Disease detection is crucial for effective disease management. In recent years, deep learning techniques, such as Convolutional Neural Networks (CNN), have shown promising results in disease detection. In this study, we propose a plant disease detection system using CNN and Arduino. The system involves capturing images of plant leaves using a camera module connected to an Arduino board. In recent years, deep learning techniques such as Convolutional Neural Networks (CNNs) have shown great promise in image-based disease detection. Additionally, the use of low-cost microcontrollers like Arduino can provide a costeffective solution for real-time disease detection in the field. This paper proposes a plant disease detection system that combines CNN and Arduino for early and accurate disease detection. The system utilizes a CNN model to classify plant disease images and an Arduino board to analyze the results and provide real-time feedback to the user. The proposed system is tested on a publicly available dataset of plant disease images, achieving high accuracy, and demonstrating its potential for practical use. The results show that the proposed system can provide an affordable and efficient solution for early plant disease detection, facilitating prompt action and reducing crop losses.
An Artificial Intelligence Driven Review of Literature on the Detection of COVID-19 Disease from Radiographic Images
Authors: Srivastava Arshita , Mishra Shubham
Published: June 2023

Abstract: Pandemic of COVID-19 has attained significance in the field of research and innovation. After the arrival of various variants of covid 19, it demands more research for the identification and analysis of features. Medical investigations are found to be risky and costly. And so, the use of artificial intelligence techniques become more popular for the classification of covid 19 features. Such AI techniques perform recognition with accuracy and time effective in order to control diagnosis. The use of AI for COVID-19 detection has emerged as a promising solution. The proposed review of literature performs the analysis of the effectiveness of the AI models such as CNN and Inception-ResNet-V2, for the identification of COVID-19 from the radiographic scans. While these models have shown promising results, it is important to use them as an additional tool to assist medical professionals, rather than as a replacement. Ethical considerations such as reliability, transparency, and fairness must also be considered in the development of these models. Additionally, the data used to train and test these models should be diverse, representative, and validated to avoid potential biases and improve generalization capabilities. Further research and collaboration between medical professionals and AI experts are needed to advance the management and deployment of AI models for the detection of COVID-19.
An Approach to Managing Public Services that uses Big Data and Cloud Computing
Authors: Shroff Meet
Published: June 2023

Abstract: Governmental regulations have accelerated the development of information technology and resource grouping. One area of "digital gold" that is extremely practical and scientific is large-scale data mining. This is not simply a contemporary issue; it also calls for the rapid expansion of public service. As a result, it is possible to fully realise the advantages of information, improve service effectiveness, and close the service gap. Due to its speedy accounting, low memory requirements, and effective resource allocation, cloud computing has grown in popularity. Big data was therefore used in this work to analyse the current state of public cloud services, and fuzzy evaluation was used to analyse accurate monitoring. Eventually, the structure of the public service was enhanced, and a strategy for the precise organisation of the complete big data-driven public service process was created. According to a fuzzy comprehensive assessment, the design value and data entropy of public cloud services were increasing exponentially; the average design value of the accurate organisation for cloud-based government services was around 4.35, and the average significance of data entropy was around 0.98. Furthermore, big data-driven precision organisation of social public social welfare outperformed traditional precision monitoring of cloud-based services for the public, with results that suggested effects were 7% higher and overall capacity was 9% higher than the compared techniques.
Human Activity Recognition System
Authors: Giri Pranit
Published: June 2023

Abstract: Almost every university has its management system to manage the students' records. Currently, even though there is a student management system that manages the students' records in Universiti Malaysia Sarawak (UNIMAS), no permission is provided for lecturers to access the system. This is because the access permission is only to top management such as Deans and Deputy Deans of Undergraduate and Student Development due to its privacy setting. Thus, this project proposes a system named Student Performance Analysis System (SPAS) to keep track of students' results in the Faculty of Computer Science and Information Technology (FCSIT). The proposed system offers a predictive system that can predict the student's performance in the course "TMC1013 System Analysis and Design", which in turn assists the lecturers from the Information System department to identify students that are predicted to have bad performance in the course "TMC1013 System Analysis and Design". The proposed system offers student performance prediction through the rules generated via the data mining technique. The data mining technique used in this project is classification, which classifies the students based on students' grades. Keywords- Student performance; student analysis; data mining; student performance analysis; classification; prediction; system
Decentralized Voting System Using Blockchain
Authors: Raskar Atharva
Published: June 2023

Abstract: India is the world's huge democracy and has the greatest population. The necessity for more advanced technology is brought on by security flaws in the current voting system. Although there are difficulties in creating a safe electronic voting system, there are advantages such as ease and cost savings. There are problems that need to be solved, like user authentication and faulty equipment. In order to increase security and transparency, the suggested solution calls for building a secure voting system that makes use of blockchain technology. The dependability and integrity of the Indian election process would increase as a result of this, which would guarantee the users' legitimacy and safeguard against manipulation or fraud.
Rainwater Harvesting
Authors: Sinha Mayank
Published: June 2023

Abstract: One of the severe issues that is well recognized on the planet is the water scarcity. Overexploitation of groundwater and surface water resources is the outcome of population growth, urbanization, and industrial expansion. Due to uneven rainfall, the traditional water sources, such as wells, rivers, and reservoirs, are unable to supply all of the water needed .While a new water source is being investigated by the rainwater gathering system. Utilizing rainwater is the study goal, which is closely related to the idea of protecting the environment. This study examines the Rain Water Harvesting (RWH) system as a substitute for the BBDITM H-block as a source of water. By taking into account nearly all technological aspects, the development system satisfies social requirements and maybe implemented in both urban & rural areas.
Shortest Path Finding Visualizer
Authors: Haldavanekar Prof. Sayali , Mahadwad Sushant , Dighe Satyam , Suryawanshi Kunal , Rai Deepak
Published: June 2023

Abstract: Visualization is an effective way to learn concepts faster than traditional methods. Modern technologies make it possible to create e-learning tools, which also greatly contribute to improving the quality of computer science teaching. The goal of this project is to create a Pathfinding Visualizer, a web-based e-learning tool that can be used to visualize the shortest path algorithm. Conceptual applications of the project are illustrated through implementations of algorithms such as Dijkstra's and DFS. This project aims to perform all these tasks with some knowledge of HTML, CSS, JavaScript and React framework. Since the final product is a web application, users can easily see and learn how the algorithm works. Ease of use of the project provides users with a simple instruction manual. The first results using the app promise the benefits of this learning tool for students who have a good understanding of the shortest path algorithm.
Impact of Urbanization on Landuse/Landcover Change in Old Cuttack and Sikharpur Zone of Cuttack Municipal Corporation
Authors: Biswal Sushmita , Kumar Santosh , Dhal Rohan
Published: June 2023

Land use mapping is fundamental for assessment, managing and protection of natural resources of a region . • The information on the existing land use is one of the prime pre-requisites for suggesting better use of terrain. • Land use maps are valuable tools for agricultural and natural resources studies. , With the growth of population and socio-economic activities, natural land cover is being modified for various development purposes. • Land use mapping is an important tool for land management and monitoring. • The rapid expansion of urban areas due to rise in population and economic growth is increasing additional demand on natural resources thereby causing land-use changes especially in megacities. • Therefore, serious problems associated with rapid development such as additional infrastructure, informal settlements, environmental pollution, destruction of ecological structure and scarcity of natural resources has been studied carefully using remote sensing and GIS technologies for a rapidly grown city
Analysing and Enhancing Agricultural Productivity-Banki-Dampara Block, Cuttack District, Odisha
Authors: Das Soumya Priyadarshini , Swain Swapna Sarita , Das Shrestha
Published: June 2023

Abstract: This study has been undertaken to analyses the factors those are affecting for the less productivity and enhance the agricultural productivity in Banki-Dampara Block of Cuttack District. The agricultural productivity decreases day by day that is 51.08% from 2010-2022. The non agricultural area also increases day by day that is 22.5% from 2010-2022.There are mainly four factors are affecting the agricultural productivity such as lack of irrigation facilities , frequently flood attack , frequently attack of elephant & pest. This research will provide some solutions for increasing the agricultural productivity in near future
Introduction
Authors: Morrison Sheila , Bergmanson Jan
Published: June 2023

This special issue of JCLRS outlines some of the proceedings and topics discussed.
IOP and Glaucoma
Authors: Nau Cherie
Published: June 2023

Scleral lenses have steadily gained popularity and their efficacy in managing complex ocular disease is increasingly being recognized. They provide an exciting opportunity to allow us to improve vision and comfort in some of our most challenging patients. However, enthusiasm for the potential benefits of scleral lenses should not overshadow potential complications that could be caused by scleral lens wear. One specific area of concern is the possibility that scleral lenses may cause an increase in intraocular pressure (IOP).
Use of Standardized Patients in Mental Health Simulation
Authors: Irwin Amber , Colella Christine
Published: June 2023

Standardized patients (SP) have been utilized in nursing education lab simulations to offer students a realistic and standardized environment for practicing skills. The use of the SP for mental health education has not been widely used. Due to a lack of mental health clinical sites and safety concerns, using a SP in mental health nursing education is an exciting and viable option. Preparing and using the SP could be a way to make sure nursing students get the experience without the anxiety.
O reggae em São Luís: identidade cultural e o surgimento da Jamaica brasileira
Authors: Marques Matheus Andrade
Published: June 2023

O presente artigo discute a chegada e consolidação do reggae em São Luís. Constata-se que São Luiz é o território fora da Jamaica onde o gênero musical mais faz sucesso, tendo incorporado pela sua população, principalmente por negros, uma série de hábitos particulares durante a apropriação do reggae jamaicano, deste modo, o regueiro de São Luís criou laços únicos com o ritmo jamaicano e essa relação perdura até os dias atuais. Estes aspectos contribuíram para que São Luís fosse concebido como ‘Jamaica Brasileira’. O objetivo da pesquisa é analisar a relação do reggae com a população ludovicense, suas particularidades e simbolismos. Como resultados, identificou-se que a relação sociedade e reggae existente em São Luís possuem singularidades, que expressam aspectos históricos, culturais, raciais e de resistência.
Gender diversity in the workplaces: Regulatory framework, public policies, and a possible future scenario
Authors: Calabrese Giuseppe , Bianco Rosario , Anjomrouz Elaheh
Published: June 2023

The concept of diversity management refers to the business strategy adopted by organizations for the recruitment, retention, and inclusive development of individuals from a variety of backgrounds. Since then, due to the huge socio-cultural, political, and economic transformations, along with the globalization of trade and business models, on the one hand, and the migration flows of people across the globe, on the other, the degree of diversity within organizations has grown exponentially, diversity management has become strategic, and copious literature on this issue has developed over the last three decades. After a brief introduction to the wide field of diversity management, the paper focuses attention on the specific issues of gender diversity in the workplace. Particularly, the analysis concern women’s access to the workplace and the related education and training paths, economic treatment, career opportunities, and the possibility of having in charge leadership roles in organizations. Subsequently, the gender gap is explored by presenting a snapshot of the situation in the European Union (EU) and Italy, also considering the consequences of the COVID 19 pandemic. Then the attention is focused on the current Italian regulatory framework. Finally, some concluding remarks and a possible scenario are presented.
Rare single‐nucleotide variants of MLH1 and MSH2 genes in patients with Lynch syndrome
Authors: Mirabdolhosseini Seyed Mohsen , Taleghani Mohammad Yaghoob , Rejali Leili , sadeghi hossein , Fatemi Nayeralsadat , Tavallaei Mehdi , Meyari Amin Famil , Saeidi Narges , Sadeghi Amir , Aghdaei Hamid Asadzadeh , Zali Mohammad Reza , Mojarad Ehsan Nazemalhosseini
Published: June 2023

Approximately 5% of colorectal cancers (CRCs) are hereditary. Lynch
syndrome (LS), also known as hereditary nonpolyposis colorectal cancer
(HNPCC), is the most common form of recognized hereditary CRC. Although
Iran, a developing country, has a high incidence of CRC, the spectrum of
mutations has yet to be thoroughly investigated. Therefore, this study
aimed to investigate pathogenic and non-pathogenic variants in MLH1 and
MSH2 genes in Iranian patients with suspected Lynch syndrome (sLS). In
the present study, 25 peripheral blood samples were collected from
patients with sLS and high microsatellite instability (MSI-H). After DNA
extraction, all samples underwent polymerase chain reaction (PCR) and
Sanger sequencing to identify the variants in the exons of MLH1 and MSH2
genes. The identified variants were interpreted using prediction tools,
including SIFT, CADD, PolyPhen, PROVEAN, REVEL, MetaLR, and Mutational
Assessor. In our study population, 13 variants were found in the MLH1
gene and 8 in the MSH2 gene. Interestingly, 7 of the 13 MLH1 variants
and 3 of the 8 MSH2 variants were novel, whereas the remaining variants
were previously reported or available in databases. In addition, some
patients with sLS did not have variants in the exons of the MLH1 and
MSH2 genes. The variants detected in the MLH1 and MSH2 genes had
specific characteristics regarding the number, area of occurrence, and
their relationship with demographic and clinicopathologic features. We
identified two novel pathogenic/likely pathogenic variants in these two
genes. Overall, our results suggest that analysis of MLH1 and MSH2 genes
alone is insufficient in the Iranian population, and more comprehensive
tests are recommended for detecting LS.
Impact of COVID-19 on adverse reactions of SCIT in children
Authors: Li Jingjing , Chen Yanling , Ye Hong , Wang Chengyi , Zhou Qing , Jiang Liyuan , Peng Xiuling , Chen Lumin , Li Haibo
Published: June 2023

Objective: To investigate whether severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection increases the adverse
reactions of subcutaneous specific immunotherapy in children.
Methods: This study was conducted by collecting relevant data
from children who underwent house dust mite SCIT from April 3, 2021 to
March 18, 2023, including information on the time of COVID-19 infection,
symptoms, and adverse reactions after each allergen injection. A
mixed-effects model was used to analyze the changes in adverse reactions
before and after COVID-19 infection. Results: Among the records
of adverse reactions from 2658 injections in 123 children who underwent
SCIT, the overall adverse reaction rate before COVID-19 infection was
39.8% and 30.0% after COVID-19 infection. Compared with pre-infection
with COVID-19, the risks of overall adverse reactions, local adverse
reactions, and systemic adverse reactions of desensitization treatment
after COVID-19 infection were reduced (OR = 0.24, 0.31, and 0.28, all P
<0.05). Among the local adverse reactions, the incidence of
the unvaccinated group was the highest (15.3% vs. 7.1%). The incidence
of overall and local adverse reactions to SCIT decreased in 2-vaccinated
COVID-19 recipients (OR = 0.29–0.31, P <0.05)
Conclusions: SARS-CoV-2 infection does not increase the
incidence of adverse reactions to SCIT in children. SCIT can be
performed according to the course of treatment after the SARS-CoV-2
infection is controlled, just like with other common infectious
diseases.
Specific aortic regurgitation: rupture of Valsalva aneurysm causes aortic valve prolapse and spontaneous valve perforation; Concomitant ventricular septal defect
Authors: Bang-hui Lai , Qi Yang , Mingbin Deng
Published: June 2023

Severe aortic regurgitation from a ruptured Valsalva aneurysm is rare.
We report on a 28-year-old male patient was presented with a Ruptured
Sinus of Valsalva Aneurysm by Transthoracic echocardiography.
Intraoperatively, a perforated aortic lobe was found to have caused
specific aortic regurgitant flow. The patient underwent successful
surgery. Intraoperative transesophageal echocardiography provides
important information for the surgical plan.
Intercostal nerve cryoablation reduces opioid utilization after thoracotomy in children with cancer
Authors: L Kathryn McElhinney , Zeineddin Suhail , L Samantha Ahle , Goldstein Seth D. , Lautz Timothy
Published: June 2023

BACKGROUND: Intercostal nerve cryoablation (INC) has shown
promise as an adjunct method for analgesia in adults undergoing
thoracotomy but has yet to be widely used in children for this
indication. We hypothesize that INC decreases opioid utilization in
children undergoing thoracotomy for cancer operations. METHODS:
A retrospective review was performed of children who underwent
thoracotomy for a cancer diagnosis at a freestanding children’s hospital
from 2018-2023. Patient characteristics, intraoperative data, and data
on clinical course were collected. Patients were divided into those who
underwent INC and those who underwent routine care for comparison.
RESULTS: Twenty-six patients underwent 38 procedures at a
median age of 16 years (range 5-21 years). INC was performed in 23 cases
over a median of 5 intercostal levels (range 2-7). Total oral morphine
equivalents (OME) during inpatient admission were significantly lower in
INC patients (137.6mg versus 514.5mg, p=0.002). Routine care patients
were more likely to be discharged with an opioid prescription (30.4%
versus 80.0%, p=0.008). Length of stay was similar between patients
with INC and routine care (4 versus 5 days, p=0.15). There were no
differences in rates of reoperation or 30-day readmission (emergency
department (ED) or inpatient). CONCLUSTIONS: INC is a feasible
and safe adjunct for children undergoing thoracotomy for cancer. INC is
associated with reduced postoperative opioid utilization with respect to
both inpatient use and outpatient prescriptions.