bluuebunny/crossref_metadata_2025 huggingface dataset:
Interregional Investment Projects: Complexities of Law Enforcement, Limitations, Challenges
Authors:   Fund “Centre for Strategic Research”, Karavaeva Tatyana
Published: May 2022

In the article the main approaches to interregional cooperation in the investment area are analyzed. The article emphasizes the need to intensify efforts to build interregional links in order to achieve the common goals and objectives of social and economic development of the regions that are facing each of the constituent entities of the Russian Federation. It is suggested to analyze the values of the main indicators of the development of territories not only as a separate region, but also in terms of their influence and contribution to the development of the macroregion. During the study the current situation in the regions of the Russian Federation (by federal districts) was assessed. Such methods of research as analysis and comparison of key social and economic indicators together with legal acts of some regions of Russia were applied. At the same time, the paper touches upon international experience in the development and implementation of successful projects in the framework of “mega-regions”. Besides, the practice of interregional projects realization in Russia is being assessed. The main purpose of the work is to study the management of the region’s development through a set of measures used in the territory of a single constituent entity of the Russian Federation alongside with taking into account the possibilities for interregional cooperation, which are provided by the macro-region. The expediency of making changes to the existing laws and regulations, as well as the introduction of platforms of digital technologies for the coordinated management and development of the regional economy, is mentioned. As a result, it is suggested to strengthen the overall work to achieve the key goals and objectives of the regions through interregional cooperation, including the creation of joint investment agencies, the formation of a legislative framework, as well as a platform for the development of joint proposals and their promotion to the federal level.
Kuzbass: External and Internal Challenges As an Impulse for Transformation of Social and Economic System of Region
Authors:   Institute of Economics and Industrial Engineering, Siberian Branch of the Russian Academy of Sciences, Fridman Yuri , Loginova Ekaterina ,   Institute of Economics and Industrial Engineering, Siberian Branch of the Russian Academy of Sciences, Rechko Galina ,   Institute of Economics and Industrial Engineering, Siberian Branch of the Russian Academy of Sciences, Khokhrina Olesya ,   Kemerovo State University
Published: May 2022

The global energy transition, the defining factor for which is the decarbonization and the transition to a low-carbon economy, radically influenced the position of coal in the global fuel and energy supply-demand balance. Coal has long remained one of its basic elements, providing energy security for a significant number of countries. The prospect of abandoning coal as a source of energy has become a serious political and economic challenge for many states, including Russia. The risk exists not only for the owners of the coal business, but also for the regions where the coal industry is a systemic one. In Russia, first of all, it is Kemerovo oblast – Kuzbass, where budget planning depends on world coal prices, and the development strategies of the last twenty years were based on coal production growth. The article attempts to analyze the main challenges caused by the global climate agenda and the energy transition: Kuzbass may face them in the next three or four years, and in the more distant future they will only intensify. The authors identified three such challenges: environmental problems appeared in the region as a result of the activity of enterprises of coal and other industries; reduction of the capacity of the global coal market as a first step towards decarbonizatoin; development of new large coal mining centers in the eastern regions of the Russian Federation. These challenges can provoke numerous risks for sustainable development of Kuzbass. They will have the greatest impact in the 2030s – 2040s. It is when the main world economies plan to stop the growth of CO2 emissions and begin to reduce it in order to achieve carbon neutrality by 2050–2060. Kemerovo region, which is currently experiencing an increase in coal production, should prepare for a deep transformation of its social and economic system in order to be able to maintain its stability in 2030–2040. Within the framework of this article, the authors do not set the goal of a deep analysis of all risks, the results of studying these problems will be presented in the following scientific papers.
Features of Spatial Development of Territories (On the Example of Regions of the Russian Federation in the Far Eastern Federal District)
Authors:   Lomonosov Moscow State University, Molchanov Igor
Published: May 2022

The purpose of the article is to study the key factors and conditions affecting the state and spatial development of territories (based on the materials on social and economic situation of the constituent entities of the Russian Federation in the Far Eastern macroregion). The research methodology is based on the theoretical provisions of regional economic science, dialectical and systemic approaches, economic and statistical, specifically comparative, comparative and content analysis, the use of methods of logical comparison and expert assessments. The features of spatial development, which are typical for the regional level and affect not only the state and prospects of the constituent entities of the Russian Federation and federal districts, but also the entire national economy of Russia, are analyzed. The Far Eastern Federal District is a dynamically developing macroregion with a potential for economic development, which was chosen as the object of research. Based on specific material, the reasons for the differences in the social and economic situation of its constituent regions are revealed, their key macroeconomic indicators are analyzed. The starting point for the analysis is the assumption that the transformational changes in the national economic system of Russia caused by the consequences of the global pandemic crisis naturally affect the functioning of industries and territories in a spatial aspect. The expediency of application of a systematic approach to the analysis of all components of the economic subsystem of the Far Eastern Federal District is substantiated. The factors affecting the territorial and sectoral structure of the economy of the constituent entities of the Russian Federation within the Far Eastern Federal District were identified. This made it possible to present the drivers of economic growth and make suggestions in the optimization of the relationship of all economic entities within the administrative and territorial entities that have distinctive characteristics and essential features. Recommendations for the improvement of the economic and financial condition of the Far Eastern regions, achievement of a balance of subnational budgets were formulated. Productive vectors for further research can be quantitative and qualitative assessment of factors affecting the rates of economic growth, volume and structure of the GRP of these constituent entities of the Russian Federation, substantive analysis of possible areas of international cooperation in the Eurasian space.
A Quinquennial Multivariate Monitoring of the Brackish Water Zone of Hooghly Estuary, Northern Bay of Bengal, India
Authors: Mukherjee Abhishek , Ghosh Phanibhusan , De Tarun Kumar
Published: May 2022

A quinquennial study (Mar'2010-Feb'2015) was undertaken to comprehend the interrelationship of the selected ecological variables in the lower Hooghly estuarine complex. The yielded data pointed out that there was a paradigm shift after in the year 2013 as the real time data revealed
considerable changes in mean before and after that period. A total of 19 variables were considered for the study among which 4 were ecological indices derived. From the extensive study it was evident that variables such as dissolved nutrients, pH, water temperature, air temperature, turbidity,
wind speed, relative humidity and precipitation etc were all influential on the population density of phytoplankton [r-values ranging from -0.99 to +0.95 @ 95% confidence level; p-values of upto +0.99]. A 'single factor ANOVA' was performed on the normalized data sets, the 'Null hypothesis'
was rejected. To detect the set(s) where the differences in variances of means lie, two sets of t-tests were performed (assuming equal and unequal variances) where in both the cases the 'Null hypothesis' was rejected. A multivariable regression analysis was also performed [Multiple R:+0.9004;
R Square: 0.8107; Adjusted R Square: 0.7519; Standard Error: 3.1117; Observations (n): 60, at 0.05 level of significance] and the generated equation is as follows: NPP = [+47.0402] + (-0.1054) Rh + (-0.0056) Precpn. + (+0.4871) WS + (0.4080) pH + (+0.2870) Sal + (+0.2006) D. O. + (-0.9625)
aT + (+0.7120) wT + (-0.0340) Turb + (+0.0068) NO3 -N + (+0.4755) PO4 -P + (+0.0109) SiO4 -Si + (-0.6815) Chl a + (+0.0005) Den.
Bio Imaging Applications of Noble Metal Nanoclusters
Authors: Banerjee Subhamoy
Published: May 2022

Metal nanoclusters are considered as the bridge between nanoparticle and discrete noble metal atoms. It comes typically in the size range of <3 nm. They exhibit excellent photophysical properties. In the visible and near infra red (IR) range, they demonstrate fluorescence phenomena.
Also, they are more stable in biological condition. Owing to these properties, the prospect of using noble metal nanoclusters for biomedical imaging has been exploited as the conventional fluorescent dues have limited use in cellular condition. In the current article, the synthesis and imaging
application of noble metal nanoclusters have been discussed.
Cardiovascular risk among nursing workers: a cross-sectional study
Authors: Ferreira Patricia Paula Eduardo , Santos Kelli Borges dos , Griep Rosane Harter , Motta Vanessa Vieira da , Evangelista Renata Alessandra , Bueno Alexandre de Assis , Paiva Elenir Pereira de
Published: May 2022

ABSTRACT Objective: to assess cardiovascular risk among nursing workers at a public hospital. Method: a cross-sectional study, with 324 nursing workers, using a questionnaire composed of two information blocks. The first covered issues related to sociodemographic and occupational and health characteristics, and the second, the Revised Framingham Risk Score (FRS), to stratify cardiovascular risk. To assess work-related psychosocial stress, the Swedish Social Control Demand Scale was used. Results: the most prevalent modifiable risk factor for CVDs was waist circumference (75.9%), followed by overweight (43.8%), obesity (29.3%), alcohol consumption (21.9%), lipoprotein cholesterol low density (LDL) > 130 (20.7%) and hypertension (20.4%) Conclusion: it was found that 96% of workers had a low risk of developing cardiovascular disease in the next ten years, and male workers aged >40 years with shorter working hours are more likely to have cardiovascular disease.
Beyond technology: Can artificial intelligence support clinical decisions in the prediction of sepsis?
Authors: Scherer Juliane de Souza , Pereira Jéssica Silveira , Debastiani Mariana Severo , Bica Claudia Giuliano
Published: May 2022

ABSTRACT Objective: To analyze the critical alarms predictors of clinical deterioration/sepsis for clinical decision making in patients admitted to a reference hospital complex. Methods: An observational retrospective cohort study. The Machine Learning (ML) tool, Robot Laura®, scores changes in vital parameters and lab tests, classifying them by severity. Inpatients and patients over 18 years of age were included. Results: A total of 122,703 alarms were extracted from the platform, classified as 2 to 9. The pre-selection of critical alarms (6 to 9) indicated 263 urgent alerts (0.2%), from which, after filtering exclusion criteria, 254 alerts were delimited for 61 inpatients. Patient mortality from sepsis was 75%, of which 52% was due to sepsis related to the new coronavirus. After the alarms were answered, 82% of the patients remained in the sectors. Conclusions: Far beyond technology, ML models can speed up assertive clinical decisions by nurses, optimizing time and specialized human resources.
Nursing Process in the Brazilian context: reflection on its concept and legislation
Authors: Barros Alba Lucia Bottura Leite de , Lucena Amália de Fátima , Morais Sheila Coelho Ramalho Vasconcelos , Brandão Marcos Antônio Gomes , Almeida Miriam de Abreu , Cubas Marcia Regina , Chianca Tania Couto Machado , Silva Viviane Martins da , Lopes Maria Helena Baena de Moraes , Santana Rosimere Ferreira
Published: May 2022

ABSTRACT Objectives: to reflect on the global understanding of the Nursing Process concept, with emphasis on the Brazilian context. Methods: a reflection article, aligned with the vision and expertise of researchers who are members of the Nursing Process Research Network. Results: the reflection is presented in two main topics: The evolution of Systematization of Nursing Care X Nursing Process concepts and its consonance with national and international practices, and Brazilian legislation; The Nursing Process concept realignment in Brazilian legislation in line with current care, teaching and research practices. Final Considerations: the reflections were oriented to the Nursing Process’ conceptual, normative and legal issues, including elements of its historical evolution, and, with that, pointed to the need to modify the Brazilian regulation on the Nursing Process.
Solar collector for soil disinfestation to produce Meloidogyne enterolobii free tomato seedlings in semiarid conditions
Authors: Silva Aline Mayara Gonçalves Barros , Moura Maria Andreia Rodrigues de , Castro José Mauro da Cunha , Cabral Patrícia Gonçalves Castro , Ishikawa Francine Hiromi , Capucho Alexandre Sandri
Published: May 2022

ABSTRACT: In this study, we validated a solar collector for disinfest soil infested by Meloidogyne enterolobii for tomato seedlings production in semiarid conditions. An experiment using a randomized block design was conducted with six exposure times of the sieved substrate in the solar collector of zinc tubes. The treatments consisted of 0 (control), 6, 12, 24, 30 and 36 hours of exposure, with five replicates. After 12 hours of soil exposure in the solar collector, no galls were observed in the tomato roots, neither were eggs and second stage juveniles of M. enterolobii were observed in the soil. Based in the results obtained in this study, the solar collector was efficient in the disinfest of soil infested by M. enterolobii aiming production of tomato seedlings in semiarid conditions.
Molecular characterization of Corynebacterium pseudotuberculosis, C. silvaticum, and C. auriscanis by ERIC-PCR
Authors: Ramos Carolina Pantuzza , Dorneles Elaine Maria Seles , Haas Dionei Joaquim , Veschi Josir Laine Aparecida , Loureiro Dan , Portela Ricardo Dias , Azevedo Vasco , Heinemann Marcos Bryan , Lage Andrey Pereira
Published: May 2022

ABSTRACT: The aims of the present study were (i) to genotype Corynebacterium pseudotuberculosis, C. silvaticum, and C. auriscanis strains using enterobacterial repetitive intergenic consensus (ERIC-PCR), and (ii) to analyze the epidemiological relationships among isolates according to biovar (Equi and Ovis), species, host, and geographical origin of the C. pseudotuberculosis strains. Sixty-eight C. pseudotuberculosis, nine C. silvaticum, and one C. auriscanis, C. pseudotuberculosis ATCC® 19410™ strain and the attenuated C. pseudotuberculosis 1002 vaccinal strain were fingerprinted by ERIC 1+2-PCR. Field strains were isolated from various hosts (cattle, buffaloes, sheep, goats, horses, dogs, and pigs) in six countries (Mexico, Portugal, Brazil, Equatorial Guinea, Egypt, and Israel). High genetic diversity was found among the studied Corynebacterium spp. isolates, clustering in 24 genotypes with a Hunter & Gaston diversity index (HGDI) of 0.937. The minimal spanning tree of Corynebacterium spp. revealed three clonal complexes, each associated with one bacterial species. Twenty-two genotypes were observed among C. pseudotuberculosis isolates, with an HGDI of 0.934. Three major clonal complexes were formed at the minimal spanning tree, grouped around the geographic origin of C. pseudotuberculosis isolates. These results reinforce the high typeability, epidemiological concordance, and discriminatory power of ERIC-PCR as a consistent genotyping method for C. pseudotuberculosis, which could be useful as an epidemiological tool to control caseous lymphadenitis. Moreover, our results also indicate the potential of ERIC 1+2-PCR for the genotyping of other species of Corynebacterium other than C. pseudotuberculosis.
New insights on the influence of the quality of tomato seedlings on production of fruits cultivated in substracts
Authors: Diel Maria Inês , Lúcio Alessandro Dal’Col , Tartaglia Francieli de Lima , Tischler André Luís , Lambrecht Darlei Michalski , Zemolin João Alberto , Marques Lucas Encarnação
Published: May 2022

ABSTRACT: This study evaluated the relationships between the biometric characters of tomato seedlings with the production characters obtained at the end of the crop cycle, to determine how the quality of seedlings interferes with tomato productivity. An experiment was carried out in two growing seasons, in a completely randomized design, with four replications and the experimental unit consisting of five plants. The treatments consisted of seedlings with different ages, differentiated by the days after sowing (DAS): (15, 20, 25, 30, 35, and 40 DAS). After each evaluation of the seedlings, they were transplanted to the definitive production site, being evaluated until the end of the cycle. Biometric characters of seedlings and characters of fruit production were evaluated. Pearson correlation analysis and principal components (PCA) were performed to determine the relationships between the characters, path analysis to determine the direct and indirect effects, and analysis of canonical correlations between the groups of characters. In all analyses performed, weak correlation between the biometric characters of the seedlings (which evaluate the quality) with the characters of tomato fruit production in substrate cultivation was identified.
Epidemiology and economic impact of bovine cysticercosis in the state of Espírito Santo, Brazil
Authors: Rossi Gabriel Augusto Marques , Mathias Luis Antonio , Tobias Fernando Luiz , Ferraz Carolina Magri , Sobral Samilla Alves , Veloso Francielle Bosi Rodrigues , Lima José Antonio Correia , Aguiar Deivisson Ferreira , Braga Fabio Ribeiro
Published: May 2022

ABSTRACT: Bovine cysticercosis (BCC) is an important disease in Brazil due to its detection in abattoirs, resulting in economic losses for cattle farmers, and a public health corcern. Besides its importance, the knowledge about BCC epidemiology and impact remains not fully described in several areas in this country, requiring more studies. Thus, this study focused on establishing BCC prevalence in the regions and municipalities of the state of Espírito Santo from 2017 to 2019, establishing the associated risk factors, and estimating the economic losses for cattle farmers. A set of 2,330 cases of BCC was detected in the 407,529 bovine inspected by Federal Inspection Service (0.57%; C.I. 95% 0.55 - 0.60%) with a higher detection of unviable cysticercus (66.14%). The beef producers lost at least US$153,000.20 due to BCC through this period. The highest risk for BCC infection occurred in Metropolitana (OR = 9.19), Litoral Sul (OR = 7.77), Caparó (OR = 7.44), and Central Sul (OR = 7.19) mesoregions, respectively. The BCC was detected in animals from 67 municipalities and its prevalence increased in areas with high human population density (OR = 1.58;; p = 0.01). In conclusion, BCC is an important disease for beef production chain in the Brazilian state of Espírito Santo and a cause of economic losses, mainly in some areas, and urgently requires the adoption of prophylactic strategies to reduce the ocurrence of this parasite.
What is the best way to define sample size for cauliflower seedlings?
Authors: Bittencourt Karina Chertok , Souza Rafael Rodrigues de , Pazetto Stella Bonorino , Toebe Marcos , Toebe Iris Cristina Datsch
Published: May 2022

ABSTRACT: This study compared four methods for defining the ideal sample size per experimental unit to estimate the overall experimental mean for the total length, shoot length, root length, and the number of leaves of cauliflower seedlings. An experiment was carried out where the number of leaves, shoot, root, and total length were measured, and the general, perpendicular distance, linear response plateau, and spline methods were tested. While the general method may under or overestimate sample size and the sampling of 10 seedlings suggested by the spline method is still too far from the stabilization point of the curve, the perpendicular distance and linear plateau response methods are recommended to obtain results corresponding to narrower confidence interval widths. Therefore, according to the perpendicular distance method, at least 15 seedlings per experimental unit are required to estimate the overall experimental mean of cauliflower seedlings reliably for the traits here measured.
PRE-FRAILTY IN OLDER ADULTS: PREVALENCE AND ASSOCIATED FACTORS
Authors: Oliveira Adriana Delmondes de , Reiners Annelita Almeida de Oliveira , Azevedo Rosemeiry Capriata Souza de , Silva Kátia Moreira da , Silva Ageo Mário Candido da
Published: May 2022

ABSTRACT Objective: to analyze pre-frailty prevalence in older adults residing in the community and associated factors. Method: a cross-sectional study, carried out with 291 elderly people registered in Family Health Strategy units. Pre-frailty was measured using the Edmonton Frail Scale, and the other variables were measured using different instruments. Data were collected from June to August 2018. Data analysis was performed using the Mantel Haenszel chi-square test, Fisher’s test and Poisson multivariate regression. Results: pre-frailty prevalence was 69.42% (95% CI; 63.77%-74.66%). Factors associated with pre-frailty were: low education (PR=1.37; 95% CI: 1.11-1.71), dependence on basic (PR=1.39; 95% CI: 1.22-1.59) and instrumental activities of daily living (PR=1.58; 95% CI: 1.40-1.78), depressed mood (PR=1.58; 95% CI: 1.40-1.78). =1.53; 95% CI: 1.31 1.78), negative self-rated health (PR=1.39; 95% CI: 1.15-1.69), polypharmacy (PR=1.30; CI 95%: 1.13-1.50), and nutritional risk (PR=1.27; 95% CI: 1.09-1.46). Conclusion: pre-frailty prevalence was higher than that found in other studies that used the same instrument, and the variables associated with this outcome demonstrated the existence of a common phenomenon among older adults. These are important results, as they highlight the need for investment in research and preventive interventions on the clinical, functional and social conditions of this population. Furthermore, it is necessary to invest in professional training programs for the comprehensive care of older adults, especially with regard to frailty assessment and prevention.
Satisfação dos responsáveis por adolescentes com as informações recebidas para o uso dos psicotrópicos em Unidade de Saúde Mental
Authors: Matos Dafny Oliveira de , Medeiros-Souza Patrícia , Melo Renata Passos de , Menezes Ricardo Azevedo de , Tavares Noemia Urruth Leão
Published: May 2022

Resumo Objetivo: Analisar a satisfação dos responsáveis por adolescentes com as informações recebidas para o uso dos medicamentos psicofármacos. Métodos: Estudo transversal realizado em ambulatório de referência entre 2017 e 2019, em Brasília, com 173 responsáveis por adolescentes diagnosticados com transtornos mentais e comportamentais em uso de psicofármacos. O questionário Satisfaction with Information about Medicines Scale (SIMS) foi utilizado para identificar o grau de satisfação em relação às informações recebidas sobre os medicamentos. Resultados: A maioria dos responsáveis estava insatisfeita quanto às informações recebidas sobre psicofármacos (n=112; 64,7%). Destacou-se a insatisfação com as informações sobre potenciais problemas do medicamento (n=127; 73,4%), quando comparada à ação e ao uso (n=89; 51,5%). As informações sobre o impacto do medicamento na vida sexual do adolescente foram consideradas insatisfatórias ou inexistentes. Conclusões: A satisfação dos responsáveis com as informações recebidas sobre psicofármacos foi baixa. Os participantes demonstraram insatisfação com as informações sobre potenciais problemas, especialmente às relacionadas ao impacto na vida sexual dos adolescentes.
Parents’ satisfaction with information received on psychotropic drugs used by adolescents in a Mental Health Unit
Authors: Matos Dafny Oliveira de , Medeiros-Souza Patrícia , Melo Renata Passos de , Menezes Ricardo Azevedo de , Tavares Noemia Urruth Leão
Published: May 2022

Abstract Objective: To analyze the satisfaction of those responsible for adolescents with information received for the use of psychotropic drugs. Methods: Cross-sectional study carried out in a reference outpatient clinic in Brasília between 2017 and 2019. It involved 173 legal representatives of adolescents diagnosed with Mental and Behavioral Disorders using psychotropic drugs. In order to identify the level of satisfaction about the information received on psychotropic drugs, the Satisfaction with Information about Medicines Scale (SIMS) was used. Results: Most guardians were dissatisfied with the information received on psychotropic drugs (n=112; 64.7%). The dissatisfaction with information about potential problems of medication was the one that stood out the most (n=127; 73.4%) when compared to information about action and usage (n=89; 51.5%). Participants considered information on the impact of medication on the adolescent’s sexual life unsatisfactory or nonexistent. Conclusions: The parents’ satisfaction with the information received about psychotropic drugs was low. Participants showed dissatisfaction with the information about potential problems, especially related to the impact on the sexual life of their tutored.
Polymorphisms and avascular necrosis in patients with sickle cell disease – A systematic review
Authors: Leandro Márcio Passos , Almeida Natália Damasceno , Hocevar Lara Santana , Sá Cloud Kennedy Couto de , Souza Amâncio José de , Matos Marcos Almeida
Published: May 2022

Abstract Objective: To systematically establish whether there is an association between polymorphisms and avascular necrosis in patients with sickle cell disease. Data source: The review, conducted according to PRISMA guidelines and registered with PROSPERO, was based on research of studies in PubMed, SciELO, LILACS, BVS databases and in the gray literature (Google Scholar and Open Gray) published until June 2020. The STROBE initiative was used to analyze the articles’ quality. Data synthesis: Ten articles were selected from the databases and two were included through manual search, totaling 12 studies. All samples gathered 2,362 patients. According to STROBE, seven studies fully and/or partially covered more than 70% of the essential items and two studies reached less than 60%, with an overall variation of 86.4–54.5%. The results indicate that polymorphisms in the genes of the bone morphogenetic protein 6 (BMP6), Klotho (KL) and Annexin A2 (ANXA2) may be associated with osteonecrosis in the context of sickle cell disease. Six articles addressed the polymorphism in the MTHFR enzyme gene, but only one found a positive association. Polymorphisms associated with the DARC receptor, the ITGA4 gene, CD36 and thrombophilia protein genes were not associated in any of the studies. Conclusions: The results indicate that the polymorphisms in BMP6, Klotho and ANXA2 genes may be associated with avascular necrosis in patients with sickle cell disease. However, in order to confirm these genetic changes as risk factors, further studies with greater statistical power and methodological rigor are needed.
Evidências de alterações na linguagem oral de crianças nascidas a termo pequenas para a idade gestacional: uma revisão sistemática
Authors: Rios Noemi Vieira de Freitas , Fernandes Luciene da Cruz , Andrade Caio Leônidas Oliveira de , Magalhães Luan Paulo Franco , Santiago Ana Cecília , Alves Crésio de Aragão Dantas
Published: May 2022

Resumo Objetivo: Realizar uma revisão sistemática para verificar a associação entre o nascimento a termo de crianças pequenas para a idade gestacional (PIG) e os desfechos no desenvolvimento da linguagem oral. Fontes de dados: Artigos dos bancos de dados MEDLINE/PubMed, Web of Science, Embase, LILACS, SciELO e Cochrane Library foram identificados, selecionados e avaliados criticamente por dois revisores independentes e um juiz, às cegas, sem restrições de idioma e período de publicação. A ferramenta PRISMA foi utilizada e foram incluídos estudos originais envolvendo crianças nascidas a termo e PIG, desfechos relacionados a aspectos do desenvolvimento da linguagem oral, bem como o uso de testes, escalas e/ou questionários específicos para a investigação, cuja metodologia estava descrita na íntegra, com crianças como população-alvo. Síntese dos dados: Nove artigos foram incluídos a partir dos critérios de elegibilidade. Os estudos demonstraram que nascer PIG pode interferir em aspectos relacionados à linguagem e relataram que as chances de crianças PIG apresentarem um desempenho inferior são maiores quando comparadas as com tamanho adequado para a idade gestacional. Observou-se que os diferentes estudos não tinham um delineamento uniforme e seus objetivos eram bastante diversificados. Além disso, poucos focavam em questões relacionadas à avaliação da linguagem e foi possível notar uma variabilidade de instrumentos utilizados para investigar esse domínio. Conclusões: Os efeitos do baixo peso ao nascer em nascidos a termo persistem além do período neonatal e podem ter impacto no desempenho infantil, principalmente no que se refere ao desenvolvimento da linguagem oral.
Evidence of changes in the oral language in children born full-term and small for gestational age: a systematic review
Authors: Rios Noemi Vieira de Freitas , Fernandes Luciene da Cruz , Andrade Caio Leônidas Oliveira de , Magalhães Luan Paulo Franco , Santiago Ana Cecília , Alves Crésio de Aragão Dantas
Published: May 2022

Abstract Objective: To perform a systematic review in order to verify the association between full-term birth of small for gestational age (SGA) children and the outcomes in the development of oral language. Data source: Articles from MEDLINE/PubMed, Web of Science, Embase, Lilacs, SciELO and Cochrane Library databases were identified, selected and critically evaluated by two independent reviewers and a judge, blindly, without language restriction and publication period. The PRISMA tool was used, and original studies with a theme involving children born full-term and SGA were included, outcome related to aspects of oral language development, as well as the use of tests, scales and/or specific questionnaires for the investigation, whose methodology was described in full, with children as the target population. Data synthesis: The researchers included nine articles based on the eligibility criteria. Studies have shown that being born SGA can interfere in aspects related to language and reported greater chances of under performance in SGA children when compared to children with appropriate size for gestational age. It was observed that the different studies did not have a uniform design, and the objectives were quite diverse. Furthermore, few of them had as focus issues related to the assessment of language, as well as the variability of instruments used to investigate this domain. Conclusions: The effects of low weight for gestation age in full-term infants continue beyond the neonatal period and may impact on children’s performance, mainly with regard to oral language development.
Dietary patterns and associated factors of children under two years of age born prematurely
Authors: Godinho Ana Paula Kulig , Conceição Amanda de Oliveira da , Rodrigues Elisa Leite , Siqueira Ilanna Mirela Becker Jorge , Taconeli Cesar Augusto , Crispim Sandra Patrícia , Dias Marcia Regina Messaggi Gomes , Almeida Claudia Choma Bettega
Published: May 2022

ABSTRACT Objective: To identify the dietary patterns and associated factors of children aged between 6 and 23 months, born prematurely and assisted at a University Hospital in Curitiba, state of Paraná, Brazil. Methods: The parents or guardians of the 135 children were asked about their children’s eating habits and the family’s socioeconomic and demographic conditions. Information regarding birth and health history were obtained from medical records. Data on food consumption were subjected to exploratory factor analysis and the principal component analysis method was used to estimate the factor loads. Multiple linear regression was performed to verify possible associations. Results: Two dietary patterns were observed: “unhealthy” and “healthy.” The “unhealthy” pattern was significantly associated with maternal age, the child’s corrected age, and gestational age at birth. The “healthy pattern” was associated with the child’s corrected age. Maternal age and child’s corrected age remained significant after multiple regression analyses. For the “unhealthy” pattern, a positive effect was observed, suggesting that the consumption of this pattern is higher as the child’s age increases and less intense for children with mothers aged 30 years or older. For the “healthy” dietary pattern, the same two variables showed statistical significance. The authors observed a direct proportion between the age and consumption of food groups in both patterns. Conclusions: These results indicate the importance of nutritional education for younger mothers regarding their children’s eating practices, especially as the child grows.
Avaliação das propriedades físicas e térmicas de cerâmicas refratárias produzidas com cinza da casca de arroz e alumina calcinada
Authors: Quevedo Juliana Calage , Tier Marco Antonio Durlo , Marangon Ederli , Cenci Charles Severo
Published: May 2022

RESUMO A casca do arroz aparece como um subproduto de grande importância para a geração de energia devido ao seu elevado poder calorífico, assim como as cinzas resultantes do processo de queima que são ricas em sílica. O objetivo principal deste trabalho foi avaliar os efeitos da incorporação da cinza da casca de arroz e da alumina calcinada nas propriedades físicas e térmicas de cerâmicas refratárias. As matérias-primas foram caracterizadas quanto à composição química pela Fluorescência de Raios-X e composição de fases por Difração de Raios-X. As propriedades físicas investigadas foram porosidade aparente, absorção de água, densidade aparente, retração linear e variação de massa. As propriedades térmicas avaliadas foram resistência ao choque térmico à temperatura de 500 ºC e a condutividade térmica. A cinza da casca de arroz empregada nesta pesquisa confirmou seu potencial como precursor cerâmico no desenvolvimento de refratários silicosos. Após a sinterização observou-se a presença das fases cristobalita, alumina-α, mulita e quartzo. Com a adição de 10 % de cinza de casca de arroz observou-se um aumento da retração linear das cerâmicas. A porosidade aparente, a absorção de água, a condutividade térmica e a resistência ao choque térmico aumentaram com a adição de alumina calcinada, em particular no percentual de 30 %. As modificações nas propriedades podem ser explicadas pelo aumento da porosidade e pelas fases, em especial alumina-α. A resistência ao choque térmico e condutividade térmica apresentaram valores aceitáveis para o uso na indústria siderúrgica.
Chemical treatment of sugarcane bagasse and its influence on glyphosate adsorption
Authors: Bezerra Williene Faria da Penha , Dognani Guilherme , Alencar Laura Neves de , Parizi Marcela Prado Silva , Boina Rosane Freire , Cabrera Flávio Camargo , Job Aldo Eloízo
Published: May 2022

ABSTRACT Due to the production rates of sugarcane, nowadays, the sugarcane bagasse stemming in the sugar and alcohol industry is the agro-industrial waste produced in greater volume throughout in Brazil. In 2019, about 192 million tons of this waste were generated. The use of this waste has been the aim of researches around the world, with emphasis on applications that aim to meet the prerogatives of the concept of circular economy. Within this scenario, sugarcane bagasse (SB) was treated in an alkaline medium, forming an adsorbent material, SBNaOH. The effects of chemical treatment were evaluated for surface properties and for glyphosate removal in an aqueous medium. The adsorptive phenomenon was studied through isotherm tests. The results obtained were fitted to classical models of Langmuir, Freundlich and Dubinin-Radushkevich. The characterization indicated that the chemical treatment promoted an important change in the surface of the residue, increasing the surface area. SB and SBNAOH had a feasible behavior as adsorbent and good performance in the removal of the herbicide, presenting values greater than 65% of under all working conditions. The theoretical adsorption saturation governed by Dubinin-Radushkevich (qS) was in the order of 8.988 mg/g (R2=0.988) for SB at 120 minutes of contact and maximum adsorption capacity by Langmuir (Qmax) was 13.720 mg/g (R2=0.984) for SBNaOH at 40 minutes of contact. The process was governed by the exchange or sharing of electrons. The adsorbate is distributed heterogeneously on the SB surface, justifying the presence of active sites with greater ionic strength, and homogeneously on the SBNaOH surface (monolayer). In general, the treated sugarcane bagasse, coming from an agro-industrial residue, proved to be an alternative and promising biosorbent for the removal of glyphosate from aqueous systems, thus generating a new application of this residue.
Desenvolvimento de filmes biodegradáveis de poli(ácido láctico) e proteína isolada de soja produzidos via extrusão plana
Authors: Morais Ana Carolina Lemos de , Silva Thyago Camelo Pereira da , Castro Layara Lorrana Ribeiro Leite de , Barbosa Renata , Alves Tatianny Soares
Published: May 2022

RESUMO Com o agravamento dos problemas ambientas causados pela má gestão de resíduos sólidos, os polímeros biodegradáveis surgem como alternativas de materiais sustentáveis que podem de minimizar o impacto ambiental. Diante da demanda urgente por produtos sustentáveis, o presente trabalho teve como objetivo desenvolver filmes a base poli (ácido láctico) (PLA) e a proteína isolada de soja (SPI) via extrusão plana para estudo como potencial aplicação em embalagens para alimentos. Os filmes foram produzidos em cinco diferentes formulações: a matriz pura de PLA como filme controle; PLA com 3 e 5% da proteína isolada de soja, PLA com 3 e 5% da proteína isolada de soja com o acréscimo de 1,5% de glicerol, e analisados via termogravimetria, espectroscopia de infravermelho, transmitância por UV-vis e ângulo de contato. O resultados indicaram que a inserção dos componentes à matriz de PLA levou a redução da estabilidade térmica dos filmes, que também não apresentaram interação química entre os seus componentes. As partículas de soja, melhor dispersas na matriz em função da presença do plastificantes, auxiliaram na redução da transmitância dos filmes, e na formação de sistemas hidrofílicos.
Um programa de educação musical para desenvolvimento da habilidade de leitura
Authors: Rocha Fábio
Published: May 2022

Tanto a linguagem verbal quanto a música se baseiam em padrões temporais da informação auditiva, ou seja, no seu ritmo. O ritmo da fala se dá pela variação da amplitude, ou volume, de cada sílaba, assim como das sílabas acentuadas, o que ocorre por volta de 0,2 e 0,5 segundos respectivamente, ou seja, nas frequências entre 5 e 2 hertz. A percepção desses ritmos é uma das principais pistas para que as crianças possam começar a distinguir as sílabas das palavras. Crianças disléxicas apresentam dificuldades para distinguir as sílabas tônicas e defasagem no treinamento rítmico com batidas em 2 hertz. Por isso, tem sido proposto que um treinamento musical, que envolva habilidades de precisão temporal poderia auxiliar crianças disléxicas a remediar seu prejuízo no processamento temporal da fala. Neste artigo justificamos e propomos uma intervenção musical para ajudar crianças a aprenderem a ler, tendo ou não dificuldades de aprendizagem. Essa intervenção consiste em um conjunto de atividades elaboradas para trabalhar habilidades rítmicas, fonológicas e de leitura com o uso de canções infantis.
Empagliflozin Changes Urine Supersaturation by Decreasing pH and Increasing Citrate
Authors: Harmacek Dusan , Pruijm Menno , Burnier Michel , Muller Marie-Eve , Ghajarzadeh-Wurzner Arlène , Bonny Olivier , Zanchi Anne
Published: May 2022

Clinical Trial registry name and registration number: Empagliflozin and Renal Oxygenation in Healthy Volunteers (EMPA-REIN), NCT03093103
Color and Architecture: Walter Gropius and the Bauhaus Wall-Painting Workshop in Collaboration, 1922-1926
Authors: Ridler Morgan Jane
Published: May 2022

The Bauhaus was rooted in the idea of collaboration between artist and craftsman and the visual arts and architecture. No medium was more dependent on this spirit of cooperation than painting. Instead of easel painting, Walter Gropius, an architect and the founding director, promoted wall painting. He involved the school’s Wall-Painting Workshop in many of his private and official Bauhaus commissions, however these collaborative relationships were never easy. This essay examines four projects involving Gropius and Bauhaus wall painters from 1922 to 1926: the Municipal Theater and Haus Auerbach, both in Jena; Gropius’s office in Weimar; and the Bauhaus building in Dessau. In these projects, the role of paint and color in architectural form emerged as a key issue and point of conflict between painter and architect. Wassily Kandinsky' 1924 memo on wall painting made it clear that color could emerge with form (Entstehen), accompany form (Mitgehen), or be in opposition to form (Entgegengesetzte) - a group of terms that might describe both the effects of wall painting and the nature of collaboration. Early on, painters such as Oskar Schlemmer and Alfred Arndt envisioned dynamic and colorful paintings in architecture. However, these transformative effects threatened to dematerialize the architecture itself, and as the 1920s progressed, Gropius increasingly rejected bold pictorial wall paintings or lively painting schemes, opting instead for restrained subordinate color. By 1926, Hinnerk Scheper, the leader of the Wall-Painting Workshop, used paint to subtly and functionally accentuate and enhance buildings. In their collaborations with Gropius, the Bauhaus wall painters transitioned from independent cooperators to subordinated collaborators, and ultimately they developed an approach in which color yields to the demands of architecture.
Emergent General Surgical Patient: Evaluation Patterns in the Emergency Department
Authors: Harpole Bethany , Helmer Stephen , Quinn Karson , Chang Howard , Brown Nicholas
Published: May 2022

Introduction.  Emergency general surgery patients represent a growing segment of general surgical admissions and national healthcare burden.  A paucity of literature exists evaluating the work-up of these patients presenting to the Emergency Department (ED), particularly possible evaluation differentials between emergency physicians and physician assistants or advanced practrice registered nurses (PA/APRNs).  The purpose of this study was to evaluate differences in ED work-up of general surgical patients between emergency physicians and PA/APRNs.
Methods.  A retrospective review was conducted of patients presenting to the ED with the chief complaint of abdominal pain.  Demographic data, evaluating provider, laboratory and imaging tests, diagnostic data, and disposition were obtained.
Results.  Patients median age was 53.5 years, with 49% male and 81.6% Caucasian.  Emergency physicians saw a majority (61.2%) of patients.  Emergency physicians saw older patients (62.0 vs. 45.5 years, p=0.017), and more patients that were anemic (28.3% vs. 14.3%), or with elevated creatinine levels (46.7% vs. 25.7%). There was no significant difference between groups for time in the ED (6.1 ± 2.4 vs. 5.7 ± 2.6 hrs, p=0.519), time to surgical consult (3.4 vs. 3.3 hrs, p=0.298), or time to OR (29.5 vs. 12.0 hrs, p=0.075).  Patients seen by emergency physicians had a longer length of hospital stay (4.5 vs. 2 days, p=0.002).
Conclusions.  Time in the ED and time to surgical consult did not vary between groups although patients first seen by emergency physicians had potentially higher acuity.  Decreased hospital length of stay in patients seen by PA/APRNs may reflect disease-specific differences.
Workflow for human placental ECM proteomics v1
Authors: Saviola Anthony , C Hansen Kirk
Published: May 2022

Described here is the workflow used by the Female Reproductive Tissue Mapping Center at UCSD to generate extracellular matrix proteomics (ECM) data from human placenta.
Bladder leiomyosarcoma originating from the muscular elements of the bladder mucosa (clinical case)
Authors: Reva I. A. , Nyushko K. M. , Plekhanova E. N. , Sanikovich V. D. , Chernushenko A. S. , Akhvlediani N. D. , Pushkar D. Yu.
Published: May 2022

Leiomyosarcoma of the bladder is an extremely aggressive malignant tumor. Today in the world literature there are a little more than 200 described cases of bladder leiomyosarcoma. In all the cases described, the neoplasm originated from the proper muscle layer of the bladder. In this work, we present a unique clinical case – bladder leiomyosarcoma originating from the muscular elements of the bladder mucosa.
Review of the article “Laparoscopic partial nephrectomy: results of various surgery techniques”
Authors: Perlin D. V.
Published: May 2022

.
Apalutamide compared with darolutamide for the treatment of non-metastatic castration resistant prostate cancer: efficacy and tolerability in a matching-adjusted indirect comparison
Authors: Chowdhury S. , Oudard S. , Uemura H. , Joniau S. , Dearden L. , Capone C. , Van Sanden S. , Diels J. , Hadaschik B. A.
Published: May 2022

.