bluuebunny/crossref_metadata_2025 huggingface dataset:
Characterization of a pediatric population during the COVID-19 pandemic in a Brazilian Cancer Center
Authors: Raniero Jessica Talita Mariana Wicthoff , Rocha Poline Spitti , Fernandes Carlos Eduardo Ramos , Duarte Maria José Clemente , Souza Fabiana Quinto de , Breves Elaine Cristina , Piotto Luciana Mariano Palanch , Costa Cecilia Maria Lima da
Published: March 2023

Introduction: There is divergence between the severity and mortality rate in oncological children depending on the country or the health center studied, therefore, it was identified the need to develop a study, with the objective of characterizing this population and identifying the reason why the patient is submitted to the examination for research of COVID-19 and its clinical outcome. Methods: Descriptive, retrospective study carried out between February 2020 to February 2022. Patients younger than 18 years of age during treatment at a Brazilian Cancer Center. Results: 668 patients were identified. Divided into two groups: Group 1, 122 (18%) presenting clinical symptoms and Group 2, with 546 (82%) patients who submitted to exam collection prior to the surgical procedure and/or imaging exam. The median age between the groups was 9 and 7 years, respectively. Almost all patients in Group 1, had symptoms related to COVID-19 and all who had feverish neutropenia belonged to this group. The most prevalent underlying disease in Group 1, was hematological and in Group 2, venous malformation. Of the total, 27 (4%) patients tested positive and only one patient died. Conclusion: COVID-19 affected both genders and its severity were independent of underlying disease or age. The protection and prevention measures throughout the period of the pandemic, allowed the low rate of contamination and severity and mortality in the patients of this study not to interrupt the treatment and its follow-up.
Why discuss sexual and gender diversity in school?
Authors: Sousa Sara Gonçalves Figueredo de , Mota Paula Alexandra Trindade , Brito John Jamerson da Silva , Silva Cynthia Valéria de Souza , Zaparoli Witembergue Gomes
Published: March 2023

The uniqueness of different subjects and cultures within the school leads us to reflect on the socialization processes that take place in this environment of social relations. Several currents have been propagating ideas and producing theories, in order to categorize relationships that involve equality, inequality and difference. The purpose of this work is to investigate how gender and sexual diversity issues are addressed in the school context and to try to think about sexual and gender diversity in school from a relational perspective, problematizing the role of the teacher in an attempt to seek the essentialization of identityidentitár ia. Understanding this issue as indispensable for discussions on this theme, and bringing not only authors who work with gender and sexuality, but also the contributions of analyses on culture, interculturality and the development of equity within the school. The research methodology is qualitative, and the analyses started from a bibliographic study. To support this production, works by authors such as Castro, Louro, Candau, Silva and others were used. The results show the importance of the teacher's social work in understanding and discussing the theme of sexual and gender diversity.
Childhood obesity and its complications
Authors: Vasconcelos Beatriz Ferreira , Carvalho Gabriela Peixoto , Ferreira Letícia Queiroz , Paula Valentina Borges de , Rodrigues Iara Guimarães , Pacheco Lucivania Marques
Published: March 2023

Introduction: Childhood obesity is a disease described by excessive accumulation of fat in infants and children. It is given when the Body Mass Index (BMI) is above the recommended for your age. The prevalence of obesity has grown significantly in recent decades in both developed and developing countries. Objective: Therefore, the aim of this study is to analyze the main causes of childhood obesity, as well as to describe the factors associated with this pathology. Methodology: This is a Literature Review study. For the survey of articles in the literature, a search was conducted in the following database: Virtual Health Library. The following descriptors were used to search the articles: pediatric obesity and overweight AND associated factors AND cause and its combinations in Portuguese. Results: The prevalence of obesity in children and adolescents largely reflects the most recent changes in eating patterns and physical inactivity. Urbanization, globalization, increased income, increase in durable consumer goods, among others, contributed to a set of lifestyle changes that directly affected the increase in overweight and obesity in children and adolescents. Associated with overweight is the risk factor for other chronic diseases that, happening at such an early stage of life, may predispose individuals still very young to preventable diseases and complications. Type 2 diabetes mellitus, systemic arterial hypertension, dyslipidemia, gastroesophageal reflux disease, osteoarthritis, orthopedic and postural problems, certain types of cancers in later life, social adjustment problems and depression are some of the diseases associated with childhood obesity. Conclusion: Prevention is the most efficient measure for the control of childhood obesity. Therefore, public health policies associated with educational measures and strategies that promote the incorporation of healthy habits are of great importance.
Multifunctional Resource Room A case study on the process of inclusion in municipal public schools in São Luís/MA
Authors: Silva Iran Alves da , Guimaraes Junior José Carlos , Duque Rita de Cássia Soares , Silva Poliana Kassia Nascimento , Andrade Selmiléia Franciane de , Santana Marttem Costa de , Paula Wellington Santos de , Oliveira Rubia Clara Nascimento de , Sousa Nilcelio Sacramento de
Published: March 2023

This article aimed to understand how municipal public schools in the city of São Luís/MA promote the inclusion of people with disabilities through their multifunctional resource rooms. The methodology used was the qualitative approach, where several documental analyzes took place, reflecting different lines of research on this topic. The research results point to robust legislation on education at the national and state level for special education, however, in the municipality in question, few points related to this discussion were found, which hypothetically suggests that the implementation of these policies in schools, too, is absent. And as propositions, pedagogical proposals were elaborated to contribute to the reflection of teachers and students, regarding issues related to special and inclusive education.
Superconductivity Experiments Confirm an Important Mechanism for Increasing the Maximum Critical Temperature in Cuprates
Authors: Buda Gianina
Published: March 2023

Some cuprate superconductors exhibit high critical temperatures at atmospheric pressure. To understand the underlying processes, researchers recently carried out high-pressure nuclear magnetic resonance experiments on the cuprate YBa2Cu3O6+y to determine the charge densities at the Cu and O sites of its CuO2 plane with high precision. Their results revealed that the more generous the in-plane Cu atoms are in transferring their hole content to the O atoms, the higher the critical temperatures that can be achieved.
Configuración de un sello identitario en la Universidad Católica de la Santísima Concepción, Chile
Authors: Uribe Ulloa Pablo , Muñoz Hernández Alex , Bravo Retamal Arturo
Published: March 2023

El objetivo de este trabajo es caracterizar el sello identitario de la Universidad Católica de la Santísima Concepción, Chile y sus elementos constitutivos.  Para ello se ha utilizado un método descriptivo documental, que ha permitido mostrar la relevancia de la formación valórica en las instituciones de educación terciaria de la región del Biobío, Chile, el proceso para la configuración del sello y los aportes que dicha configuración ofrece a la naturaleza fundacional de la Universidad, a los desafíos de la gobernanza y a la vinculación permanente con el medio externo.
METHODS FOR STUDYING COLLECTIVE PERFORMANCE IN SPORTS: A SYSTEMATIC LITERATURE REVIEW
Authors: Isserte Simon , Gaudin Cyrille , Chaliès Sébastien
Published: March 2023

The study conducts a systematic review focused on the methods privileged by researchers when they study collective performance in sports. For this purpose, 158 articles published between 2008 and 2019 were selected and submitted to an iterative process of qualitative analysis. Results showed that there are three main types of research methods to study collective performance in sports: (a) characterization of a high-achieving sport collective, (b) multifactorial impact analysis, and (c) experimentation of an intervention protocol. The results collected also tended to prove that research on performance in sports requires to deal with a wide range of factors at the same time, which makes it necessary to design a research method that's more systemic. Moreover, we identify and discuss two methodological approaches: “studying performance in order to infuse change” on the one hand; “infusing change in order to study performance” on the other.
Electronic cigarettes and health outcomes: umbrella and systematic review of the global evidence
Authors: Banks Emily , Yazidjoglou Amelia , Brown Sinan , Nguyen Mai , Martin Melonie , Beckwith Katie , Daluwatta Amanda , Campbell Sai , Joshy Grace
Published: March 2023

Objective

To review and synthesise the global evidence regarding the health effects of electronic cigarettes (e‐cigarettes, vapes).

Study design

Umbrella review (based on major independent reviews, including the 2018 United States National Academies of Sciences, Engineering, and Medicine [NASEM] report) and top‐up systematic review of published, peer‐reviewed studies in humans examining the relationship of e‐cigarette use to health outcomes published since the NASEM report.

Data sources

Umbrella review: eight major independent reviews published 2017–2021. Systematic review: PubMed, MEDLINE, Scopus, Web of Science, the Cochrane Library, and PsycINFO (articles published July 2017 – July 2020 and not included in NASEM review).

Data synthesis

Four hundred eligible publications were included in our synthesis: 112 from the NASEM review, 189 from our top‐up review search, and 99 further publications cited by other reviews. There is conclusive evidence linking e‐cigarette use with poisoning, immediate inhalation toxicity (including seizures), and e‐cigarette or vaping product use‐associated lung injury (EVALI; largely but not exclusively for e‐liquids containing tetrahydrocannabinol and vitamin E acetate), as well as for malfunctioning devices causing injuries and burns. Environmental effects include waste, fires, and generation of indoor airborne particulate matter (substantial to conclusive evidence). There is substantial evidence that nicotine e‐cigarettes can cause dependence or addiction in non‐smokers, and strong evidence that young non‐smokers who use e‐cigarettes are more likely than non‐users to initiate smoking and to become regular smokers. There is limited evidence that freebase nicotine e‐cigarettes used with clinical support are efficacious aids for smoking cessation. Evidence regarding effects on other clinical outcomes, including cardiovascular disease, cancer, development, and mental and reproductive health, is insufficient or unavailable.

Conclusion

E‐cigarettes can be harmful to health, particularly for non‐smokers and children, adolescents, and young adults. Their effects on many important health outcomes are uncertain. E‐cigarettes may be beneficial for smokers who use them to completely and promptly quit smoking, but they are not currently approved smoking cessation aids. Better quality evidence is needed regarding the health impact of e‐cigarette use, their safety and efficacy for smoking cessation, and effective regulation.

Registration

Systematic review: PROSPERO, CRD42020200673 (prospective).
MORAL DEGRADATION: HIGH RATE OF MARRIAGE DISPENSATION THROUGHOUT 2020-2022 IN PONOROGO
Authors: Nida Wafiah Rafifatun , Puspita Mega
Published: March 2023

Penelitian ini ditujukan untuk membahas tentang degradasi moral yang terjadi di Ponorogo. Sepanjang Tahun 2020-2022 tingkat dispensasi nikah tinggi, banyak siswa yang mengajukan dispensasi nikah disebabkan karena hamil duluan. Berdasarkan data yang ditunjukkan oleh PA Ponorogo kepada Pusat Studi Gender Dan Anak (PSGA) IAIN Ponorogo, angka Diska dari Tahun 2020 hingga 2021 memang mengalami kenaikan, tetapi tidak seluruhnya diska itu diajukan karena kehamilan. Penulisan ini disusun menggunakan metode kepustakaan (library research). Library research ini Studi kepustakaan ini dilakukan mengumpulkan berbagai sumber yang relevan dengan masalah yang dihadapi, dilanjutkan dengan memahami metode teliti untuk menghasilkan beberapa kesimpulan awal. terjadinya pernikahan dini di ponorogo ini diakibatkan oleh 3 faktor yaitu Faktornya ada beragam. Yaitu karena faktor pendidikan, ekonomi, dan budaya. namun yang lebiih perlu di garisbawahi adalah dampak dari pernikahan itu sendiri  yaitu resiko kematian saat melahirkan, Kematangan psikologis belum tercapai hingga hal tersebut berdampak pada pola asuh anak, resiko kematian Bayi yang cukup besar, bayi lahir prematur, kurang gizi, dan anak berisiko terkena hambatan pertumbuhan atau stunting, dan juga perpanjangan garis kemiskinan pada keluarga.

Kata Kunci: Pernikahan dini, degradasi moral, dispensasi nikah.
Keadilan Nilai Nilai Ekonomi Islam Dalam Akad Pembiayaan Pada BMT Mitra Mandiri Wonogiri
Authors: Setiawan Indra
Published: March 2023

Akad perjanjian kontrak yang dibuat tidak pasti dapat menjamin terlaksana dan dilakukan dengan baik. Harapan antara pihak yang melakukan perjanjian bisa mewujudkan kemaslahatan dan kemanfaatan dari sebuah perjanjian tersebut. Pasal 1338 ayat 3 KUH Perdata tegas menuliskan bahwa, ”Perjanjian harus dilaksanakan dengan iktikad baik”. Sebelum mengadakan dan menyepakati suatu kontrak, para pihak yang mengadakan kontrak harus memahami serta mengetahui syarat-syarat dalam kontrak.

Menggunakan analisa Good Corporate Governance(GCG) serta kaidah nilai –nilai Islami, guna memahami asas iktikad baik pada perjanjian kredit di BMT Mitra Mandiri Wonogiri dihasilkan berbagai temuan. Pertama, Fase utama dari sebuah perjanjian adalah tahapan penyelesaian kontrak. BMT Mitra Mandiri Wonogiri menawarkan opsi kontrak yang digunakan klien untuk analisis keuangan lebih lanjut. Analisis dilakukan untuk meminimalkan gagal bayar kontrak. Ketersediaan jaminan serta kelancaran pengembalian diasumsikan cukup guna mendorong perkembangan pembiayaan. Padahal penyelesaian suatu masalah akad mencerminkan asas iktikad baik. Kedua, secara umum pengaturan keuangan membawa keuntungan dan manfaat bagi para pihak dan menjamin keadilan hukum dan keuangan. Kesimpulan teoritis, dasar itikad baik berasal dari sejauh mana para pihak mengaplikasikan nilai - nilai pada proses kontrak, pengaturan serta kompromi. Semakin taat nilai-nilai syariah diterapkan oleh para pihak, maka semakin besar kemaslahatan dan keuntungan yang dicapai, sehingga dapat tercapai keadilan hukum dan ekonomi untuk tujuan kontraktual serta harapan pihak – pihak yang melakukan kontrak dapat terpenuhi dan sebaliknya.

KataKunci : Keadilan, Nilai -Nilai Islami, Good CorporateGovernance, Maslahah.
Vade-mecum for the elderly and for elderly care
Authors: Muylle Ferdy , Vandamme Fernand
Published: March 2023

Introducing and providing insight into many facets, aspects, challenges and problems of the elderly, of ageing and care for elderly, a comprehensive elaboration is made of Nestors: elderly and very elderly. Special attention is given to the issue if and when “do elderly couples become like cat and dog”. Intensively is discussed the impact of dyssocials, psychopaths or persons with antisocial personality characteristics in their efforts to abuse the elderly and how these can defend themselves. Between the many topics treated in the book are the problem of dementia and the challenges of the nestors’ intimacy and sexuality’ in these circumstances and in general. The challenges of intra and outside the family violence on and by the elderly is treated. From this perspective some reflections are made on other challenges of elderly and care for the elderly, especially on the need for support of conflict resolution in a specialized Nestor Juridical court. Moreover one needs to have attention for elderly people and their problems with loss of access to and leaving behind their goods, possessions, collections, knickknacks with emotional memories, etc. Nevertheless, we must also keep in mind that the group of nestors, like the group of children and actually like all age groups, is a highly variable group. Each member with his own perspective, wishes, possibilities, experiences, yet also with his many always increasing shortcomings and declining abilities. Hereby we must also not forget the reversal of values that takes place. After all, in human life we often witness the elderly helping, dominating, directing the young, even if this is sometimes unjustified and inefficient. In elderlies: the nestors, we see the opposite : young people, even children help, correct,... punish, etc. sometimes the elderlies. Yet some elderlies remain dominant, even when they are very old: even as company leaders, presidents, kings,... This makes not at all easier the challenge to integrating and building a harmonious society with a strong increasing ageing population.
Avaliação dos sintomas de depressão em pessoas com deficiência visual
Authors: Cambraia Maria Izabel de Albuquerque , Nazima Maira Tiyomi Sacata Tongu
Published: March 2023

A deficiência visual provoca alterações biopsicossociais e favorece o desenvolvimento de sintomas depressivos. Este estudo avaliou a ocorrência de sintomas de depressão na cegueira e seus determinantes e utilizou: entrevista semiestruturada; inventário de depressão de Beck; teste de acuidade visual. A amostra avaliou 68 pessoas, maioria do sexo masculino (60,3%), faixa etária acima de 50 anos (33,8%), solteiros (57,3%), ensino superior a pós-graduação (44,1%) e renda familiar entre 1-3 salários mínimos (36,7%).
Implementação da política de humanização nas Unidades de Terapia Intensiva
Authors: Ternus Brenda Fernandes , Wollmann Isabela
Published: March 2023

Esta pesquisa objetivou investigar as ações de humanização utilizadas pela equipe multidisciplinar na UTI adulto e refletir sobre sua importância para pacientes e familiares, bem como compreender os desafios encontrados para a realização dessas ações e os impactos da falta de humanização nos hospitais. Realizou-se uma revisão integrativa da literatura com busca nas bases de dados Web of Science, PubMed, Scopus e PsycNET. Foram identificados, inicialmente, 77 artigos e, após a aplicação dos critérios de inclusão e de exclusão, restaram oito artigos sobre a temática.
Entre a saudade e o aconchego
Authors: Lucini Thaís Caroline Guedes , Rieth Carmen Esther
Published: March 2023

O luto de pais que perderam filhos recém-nascidos é um processo de muita dor e sofrimento, especialmente pelo curto tempo de vida que tiveram juntos. O objetivo deste trabalho é analisar se o Memory Box influenciou o processo de luto do casal que perdeu seu filho na Unidade de Tratamento Intensivo Neonatal (UTIN). Para isso, foi realizado um estudo de caso único, na modalidade situacional com um casal, com o qual foi realizada uma entrevista em profundidade. A entrevista foi gravada e transcrita na íntegra, sendo analisada com base nos pressupostos de Minayo (2014). A partir da análise, emergiram três categorias: À espera de Pedrinho, sua chegada prematura e o ser pai e mãe na UTIN; A partida de Pedrinho; e O aconchego de lembrá-lo a partir do Memory Box. Com base nos resultados, foi possível perceber que o Memory Box tem influenciado positivamente o processo de luto dos entrevistados de diferentes formas, ficando evidente o quanto a possibilidade de recorrer aos objetos reais usados pelo filho auxilia na narrativa e na comprovação da existência real deste filho para as pessoas que não puderam conhecê-lo, provando a concretude de sua vida.
efeitos do desamparo psíquico em profissionais da saúde no atendimento de pacientes com COVID-19
Authors: Franco Lucas Jivago Lourenço , Corsino Debora Lydinês Martins , Cordeiro Sílvia Nogueira
Published: March 2023

A infecção COVID-19, causada pelo coronavírus SARS-CoV-2, foi responsável por uma pandemia de escala mundial, ocasionando grande impacto na sociedade como um todo, especialmente no âmbito da saúde. No que se refere aos profissionais da linha de frente no combate contra o vírus, sabe-se que eles foram uma das primeiras classes de trabalho afetadas pelo novo cenário. Nesse sentido, a presente pesquisa objetivou compreender os efeitos na saúde mental dos profissionais de saúde que vivenciaram o processo de cuidado de pacientes adoecidos pela COVID-19. O delineamento do estudo apresentou-se como descritivo, de natureza clínico-qualitativa. Utilizou-se de entrevistas semidirigidas, com questões abertas direcionadas a sete profissionais da saúde que atuavam no contexto de pandemia da COVID-19 em hospitais do Paraná. Os resultados e a discussão foram apresentados em forma de categorias, que foram estudadas a partir do método da análise de conteúdo de Bardin. Foi possível compreender que as vivências do ofício hospitalar para aqueles presentes na linha de frente da pandemia foram marcadas pelo desamparo psíquico, que trouxe sofrimento aos profissionais de saúde, decorrente das especificidades do tratamento dos pacientes com COVID-19, excesso de casos e falta de amparo dos órgãos competentes.
Gambaran Pengetahuan dan Perilaku Remaja Tentang Obesitas di SMA Negeri 1 Kota Tarakan
Authors: Argi Sriargianti amir , Adhar Siti Khadijah , Haris Haris , Baharuddin Rohandi
Published: March 2023

Obesitas menjadi salah satu masalah para remaja yang dipengaruhi oleh faktor pola makan yang kurang baik seperti pilihan makanan yang kurang sehat serta kurangnya kegiatan aktifitas fisik, sehingga memicu terjadinya penumpukan lemak berlebih di dalam tubuh yang dapat mengakibatkan timbulnya berbagai jenis penyakit tidak menular dan menjadi salah satu penyebab kematian di seluruh dunia.  Penelitian ini dilakukan untuk mengetahui gambaran pengetahuan dan perilaku remaja tentang obesitas di SMA Negeri 1 kota Tarakan. Penelitian ini adalah penelitian deskriptif. Pengambilan sampel dilakukan secara non probability sampling dengan quota sampling dengan jumlah 53 responden. Hasil penelitian menunjukkan karakteristik responden berdasarkan usia didapatkan hasil terbanyak kategori 17 tahun sebanyak 28 (52,4%), responden. Karakteristik berdasarkan IMT didapatkan hasil sebagian besar memiliki IMT terbanyak obesitas I sebanyak 27 (50,9) responden, karakteristik berdasarkan genetik (keturunan) didapatkan hasil terbanyak pada kategori tidak memiliki riwayat obesitas sebanyak 41 (77,4%) responden, karakteristik responden berdasarkan pengetahuan didapatkan hasil sebagian besar pengetahuan baik sebanyak 46 (86,8%), berpengetahuan cukup 3 (5,7%), pengetahuan kurang 4 (7,5%) responden, dan karakteristik responden berdasarkan pola makan didapatkan hasil sebagian pada pola makan tidak baik sebanyak 38  (71,7%) responden. Kesimpulan pada penelitian ini menunjukkan bahwa remaja yang berusia 17 tahun memiliki pengetahuan baik tentang obesitas dan perilaku pola makan.
Gambaran Penggunaan Antıhıpertensı pada Pasıen ST- Elevatıon Myocardıal Infractıon
Authors: Aulia Khofifah , Novrianti Irma , Ubrusun Jufri
Published: March 2023

ST-Elevation Myocardial Infraction (STEMI) disebabkan oleh beberapa faktor terutama akibat gangguan kardiovaskular. Adapun beberapa keluhan dari STEMI seperti nyeri dada, peningkatan enzim, dan ST elevasi pada pemeriksaan elektrokardiogram. Salah satu faktor mayor terjadinya STEMI adalah hipertensi, semakin berat kondisi hipertensi perlahan akan merusak dinding pembuluh darah sehingga terjadi pembengkakan yang mengarah pada STEMI. Tujuan dari penelitian ini untuk melihat penggunaan antihipertensi pada pasien stemi yang menggunakan terapi fibrinolitik. Metode penelitian ini bersifat deskriptif retrospektif dengan melihat catatan rekam medik pasien STEMI yang mendapatkan penanganan antihipertensi saat di Unit Gawat Darurat (UGD) dan menjalani rawat inap di Rumah Sakit (RS) “X” kota Tarakan periode 2017-2018. Berdasarkan penelitian diperoleh sebanyak 55 pasien menggunakan antihipertensi. Klasifikasi tekanan darah tertinggi saat masuk RS ada pada kondisi stage II berdasarkan JNC VII sebanyak 15 orang (27,28%) dan klasifikasi tekanan darah saat keluar rumah sakit didapati kondisi normal sebanyak 23 orang (41,82%). Antihipertensi terbanyak yang digunakan di RS “X” di kota Tarakan adalah golongan ACE-Inhibitor yaitu captopril dengan persentase 10,90% di UGD dan golongan Beta blocker yaitu bisoprolol fumarate dengan persentase 65,46% di Ruang Rawat Inap.
The Relationship between Work Motivation and Workload on Employee Job Satisfaction at PT. Pratomo Putra Teknik Palopo
Authors: Rima Rima , Indra Kusdarianto  , Samsinar
Published: March 2023

This study aims to determine the relationship between work motivation and workload on employee satisfaction at PT Pratomo Putra Teknik Palopo. The research method used was quantitative research with a total of 40 respondents. Data collection techniques were carried out by distributing questionnaires directly to employees at PT Pratomo Putra Palopo. The results of this study indicate that work motivation has a significant effect on job satisfaction, while workload has a positive effect on employee satisfaction, while workload has a positive effect on employee satisfaction because the influence of employee satisfaction has increased by 0.400 units. The regression coefficient of the work motivation variable has a positive relationship with employee satisfaction.
Assessing the Impact of Holocene Climate Change on Bioavailable Strontium Within the Nile River Valley
Authors: Simonetti Antonio , Buzon Michele , Simonetti Stefanie , Guilbault Kari , Kordofani Maha Ahmed , Miller Naomi
Published: March 2023

The impact of the climate drying during the Holocene within the Nile River Valley System (NRVS) has been the focus of recent debate in the archaeological community. It is argued that the increased contribution of aeolian material from the neighboring Sahara Desert during the last ~7,000 years has changed the isotope compositions of bioavailable Sr relative to the geological background and thus hinders provenance investigations of human remains within the NRVS. This study reports new trace element and strontium (Sr), neodymium (Nd), and lead (Pb) isotope compositions for a combined total of 125 samples consisting of human tooth enamel and various faunal samples from different time periods, and present-day botanical samples from 11 archaeological sites along the NRVS. The new isotope data combined with published data do not support a time-dependent increase in a Saharan aeolian bioavailable Sr component during the Holocene within the NRVS; in general, Sr isotope compositions for human enamel samples match those of their corresponding faunal matrices, and these define a similar range of isotope compositions over the various time periods. The Nd and Pb isotope compositions for human tooth enamel reported here also support the limited contribution of Saharan aeolian dust within the NVRS.
A APLICABILIDADE DO PRINCÍPIO DA SUPREMACIA DO INTERESSE PÚBLICO SOBRE O PRIVADO
Authors: Fonseca Kelly Patrícia Rodrigues
Published: March 2023

O Estado visando garantir a coletividade o direito à saúde, em meio a atual situação de calamidade que surgiu com o surto do vírus SARS-Cov-2 ou COVID-19, instituiu a lei 13.979/2020. Contudo, a norma supracitada gerou discussões na sociedade referente a constitucionalidade da medida de compulsoriedade de vacinação disposta no artigo 3.º. Uma parte da sociedade alega que a norma seria inconstitucional, pois, infringiria os direitos fundamentais dos indivíduos, em contrapartida, os que defendem a constitucionalidade explícita que as garantias resguardadas por meio das medidas de prevenção são; à saúde e à vida da coletividade, e que esses prevalecem sobre os direitos individuais. O presente trabalho teve como objetivo analisar as decisões do STF, em relação à compulsoriedade da vacinação, visando discutir e refletir no caso concreto a preponderância na aplicação do princípio da supremacia do interesse público sobre o privado em confronto com os direitos fundamentais individuais. Verificou-se que por tratar-se de um atrito entre os direitos fundamentais individuais e os direitos coletivos, o STF foi instado a se manifestar sobre aconstitucionalidade da norma. Nesta senda, o Tribunal julgou constitucional a compulsoriedade da vacinação, pois, não ocorre a violação da integridade física da pessoa humana, sendo preservado o direito à dignidade humana na medida imposta na lei 13.979/2020. Conclui-se que não há violação aos direitos fundamentais pelo uso da medida de vacinação compulsória, devendo preponderar o interesse da coletividade e prevalecendo a aplicação do princípio da Supremacia do Interesse Público sobre o particular. Assim, não há que se falar na inconstitucionalidade do artigo 3.º da lei 13.979/2020, sob a alegação de violação dos direitos individuais fundamentais.
ALGUMAS CONSIDERAÇÕES SOBRE A CONSTITUCIONALIDADE DAS MEDIDAS DE COMBATE E PREVENÇÃO À COVID – 19 PREVISTAS NA LEI FEDERAL Nº 13.979, DE 6 DE FEVEREIRO DE 2020
Authors: Paula Wesley Luiz Alves de
Published: March 2023

Este trabalho tem como objeto de estudo a constitucionalidade das medidas de combate e prevenção à covid – 19 previstas na Lei Federal nº 13.979, de 6 de fevereiro de 2020. A referida lei federal prevê no seu artigo 3º um rol de medidas sanitárias que poderão ser adotadas pelo gestor público para enfrentamento da emergência sanitária causada pelo Covid. Tendo em vista o extenso rol apresentado pela lei, optou-se por fazer considerações gerais sobre a constitucionalidade das medidas, como uma teoria geral, e usar como exemplo apenas a medida de quarentena decretada por estados e municípios. A decretação de medidas de combate a pandemia traz reflexos evidentes na promoção e na restrição de direitos fundamentais. A aplicação destas medidas ocasiona no caso concreto a colisão de diversos direitos fundamentais. Assim, analisou-se a constitucionalidade sob o signo da proporcionalidade das restrições adotadas, vis-à-vis os direitos afetados, como as liberdades de locomoção, trabalho, reunião, etc. O presente trabalho focou na questão da proporcionalidade das medidas sanitárias. Para tanto, socorreu-se da doutrina de Robert Alexy sobre a ponderação de princípios. Houve a análise, também, de alguns julgados mais relevantes do Supremo Tribunal Federal sobre a matéria, em especial as Ações Diretas de Inconstitucionalidade de nºs 6343 do DF e nº 6.855 e de algumas posições doutrinárias divergentes sobre a questão. Buscou-se, desta forma, à luz da teoria dos direitos fundamentais, analisar criticamente o entendimento esposado pelo Supremo Tribunal Federal. O assunto merece grande atenção da comunidade jurídica, pois ainda vivemos sobre o impacto da pandemia.
PROTEÇÃO DE DADOS E ADMINISTRAÇÃO PÚBLICA
Authors: Moreira Matheus Teixeira
Published: March 2023

Com a popularização da internet e a digitalização do cotidiano, o tema da proteção de dados tem se destacado cada vez mais no debate jurídico. A corrida pela adequação ao data privacy e a necessidade de maiores ferramentas para a tutela da privacidade fazem parte de uma realidade que tem sido imposta aos entes e agentes da sociedade, do mercado e, evidentemente, do Estado. Desse modo, a atuação da Administração Pública está condicionada à observância desse direito, em todas as suas instâncias e competências, desde administrativas ou executórias até mesmo as normativas. Nesse sentido, por meio da metodologia qualitativa e revisão bibliográfica, o presente artigo busca analisar o julgamento conjunto das ações diretas de inconstitucionalidade 6387, 6388, 6389, 6390 e 6393, no âmbito do Supremo Tribunal Federal, para investigar a controvérsia acerca da possibilidade ou necessidade de utilização de dados pessoais por entidade pública com vistas à execução de políticas públicas ao longo do estado pandêmico-emergencial instaurado no Brasil devido à pandemia de Covid-19. Buscar-se-á, ainda, compreender se o entendimento adotado pela Corte Suprema se trata de mais um caso de ativismo judicial ou se, por outro lado, constitui mecanismo de proteção ao Estado Democrático de Direito e está em conformidade com as boas práticas da proteção de dados pessoais.
A IN(EFICÁCIA) DA LEI MARIA DA PENHA NO ÂMBITO DAS MEDIDAS CAUTELARES
Authors: Guerra Isabella Nogueira Abrahão
Published: March 2023

A Lei Maria da Penha tem como foco as relações domésticas envolvendo vítima e agressor, sem prever exatamente novos crimes e penas. Assim, o objetivo não é a punição do agressor, e sim a proteção da vítima. Embora a igualdade de gênero tenha alcançado importantes avanços no Brasil, ainda há muito a ser desenvolvido, principalmente a aplicabilidade da proteção à mulher em situação de violência. Diante de alguns impasses, pode-se afirmar que a efetividade da referida Lei depende da superação de paradigmas jurídicos antigos que não mais fazem parte da atual sociedade. Nesse sentido, não é o objetivo aqui extinguir todos os aspectos referentes à Lei Maria da Penha, senão elaborar reflexões e análises sobre sua eficácia nas medidas protetivas.
A TESE DA "LEGÍTIMA DEFESA DA HONRA" VS. O DIREITO À VIDA DAS MULHERES
Authors: Caldas Rebecca de Moura
Published: March 2023

O presente artigo explana como a “tese da legitima defesa da honra” apresentada como defesa do réu no âmbito de atuação no “tribunal do júri”, pode ser uma forma de violação do direito constitucional à igualdade das mulheres perante os homens, na sociedade democrática brasileira, pelo motivo, desta deter uma herança histórica culturalmente marcada pelo patriarcalismo. Diante disso, a discussão existente entre a plenitude de defesa com o fulcro na defesa da “honra objetiva do acusado” vs. A violação do direito à vida da vítima do crime de feminicídio, como também a afetação integral de sua dignidade como ser humano, é presente na ação de descumprimento de preceito fundamental 779 (ADPF 779 – Distrito Federal). Assim, este conflito de direitos fundamentais, é um marco inicial para reconhecer que as mulheres, apesar dos avanços formais quanto aos seus direitos, ainda perece a carência de efetivação destes em âmbito material, constituindo a sua implementação social um verdadeiro desafio no seio da sociedade brasileira.
2021 SAEM Consensus Conference Proceedings: Research Priorities for Implementing Emergency Department Screening for Social Risks and Needs
Authors: Yore Mackensie , Fockele Callan , Duber Herbert , Doran Kelly , Cooper Richelle , Lin Michelle , Campbell Steffani , Eswaran Vidya , Hong Haeyeon , Gbenedio Kessiena , Stanford Kimberly , Gavin Nicholas
Published: March 2023

Introduction: Despite literature on a variety of social risks and needs screening interventions in emergency department (ED) settings, there is no universally accepted or evidence-based process for conducting such interventions. Many factors hamper or promote implementation of social risks and needs screening in the ED, but the relative impact of these factors and how best to mitigate/leverage them is unknown.

Methods: Drawing on an extensive literature review, expert assessment, and feedback from participants in the 2021 Society for Academic Emergency Medicine Consensus Conference through moderated discussions and follow-up surveys, we identified research gaps and rated research priorities for implementing screening for social risks and needs in the ED. We identified three main knowledge gaps: 1) screening implementation mechanics; 2) outreach and engagement with communities; and 3) addressing barriers and leveraging facilitators to screening. Within these gaps, we identified 12 high-priority research questions as well as research methods for future studies.

Results: Consensus Conference participants broadly agreed that social risks and needs screening is generally acceptable to patients and clinicians and feasible in an ED setting. Our literature review and conference discussion identified several research gaps in the specific mechanics of screening implementation, including screening and referral team composition, workflow, and use of technology. Discussions also highlighted a need for more collaboration with stakeholders in screening design and implementation. Additionally, discussions identified the need for studies using adaptive designs or hybrid effectiveness-implementation models to test multiple strategies for implementation and sustainability.

Conclusion: Through a robust consensus process we developed an actionable research agenda for implementing social risks and needs screening in EDs. Future work in this area should use implementation science frameworks and research best practices to further develop and refine ED screening for social risks and needs and to address barriers as well as leverage facilitators to such screening.
Optimizing Recruitment and Retention in Substance Use Disorder Research in Emergency Departments
Authors: Worth Lindsay , Macias-Konstantopoulos Wendy , Moy Lauren , Crandall Cameron , Chavez Roberta , Forcehimes Alyssa , Mandler Raul , Bogenschutz Michael
Published: March 2023

Introduction: Clinical trial recruitment and retention of individuals who use substances are challenging in any setting and can be particularly difficult in emergency department (ED) settings. This article discusses strategies for optimizing recruitment and retention in substance use research conducted in EDs.

Methods: Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments (SMART-ED) was a National Drug Abuse Treatment Clinical Trials Network (CTN) protocol designed to assess the impact of a brief intervention with individuals screening positive for moderate to severe problems related to use of non-alcohol, non-nicotine drugs. We implemented a multisite, randomized clinical trial at six academic EDs in the United States and leveraged a variety of methods to successfully recruit and retain study participants throughout the 12-month study course. Recruitment and retention success is attributed to appropriate site selection, leveraging technology, and gathering adequate contact information from participants at their initial study visit.

Results: The SMART-ED recruited 1,285 adult ED patients and attained follow-up rates of 88%, 86%, and 81% at the 3-, 6-, and 12-month follow-up periods, respectively. Participant retention protocols and practices were key tools in this longitudinal study that required continuous monitoring, innovation, and adaptation to ensure strategies remained culturally sensitive and context appropriate through the duration of the study.

Conclusion: Tailored strategies that consider the demographic characteristics and region of recruitment and retention are necessary for ED-based longitudinal studies involving patients with substance use disorders.
Prevalence and Risk Factors of Insomnia and Sleep-aid Use in Emergency Physicians in Japan: Secondary Analysis of a Nationwide Survey
Authors: Chiba Takuyo , Hagiwara Yusuke , Hifumi Toru , Kuroda Yasuhiro , Ikeda Shunya , Khoujah Danya , Imaizumi Takahiro , Shiga Takashi
Published: March 2023

Introduction: Emergency physicians (EP) are suspected to have a high prevalence of insomnia and sleep-aid use. Most prior studies about sleep-aid use in EPs have been limited by low response rates. In this study our aim was to investigate the prevalence of insomnia and sleep-aid use among early-career Japanese EPs and assess the factors associated with insomnia and sleep-aid use.

Methods: We collected anonymous, voluntary, survey-based data regarding chronic insomnia and sleep-aid use from board-eligible EPs taking the initial Japanese Association of Acute Medicine board certification exam in 2019 and 2020. We describe the prevalence of insomnia and sleep-aid use and analyzed demographic and job related factors using multivariable logistic regression analysis.

Results: The response rate was 89.71% (732 of 816). The prevalence of chronic insomnia and sleepaid use was 24.89% (95% CI 21.78-28.29%) and 23.77% (95% CI 20.69-27.15%), respectively. Factors associated with chronic insomnia were long working hours (odds ratio [OR] 1.02, 1.01-1.03, per onehour/ week), and “stress factor” (OR 1.46, 1.13-1.90). Factors associated with sleep-aid use were male gender (OR 1.71, 1.03-2.86), unmarried status (OR 2.38, 1.39-4.10), and “stress factor” (OR 1.48, 1.13-1.94). The “stress factor” was mostly influenced by stressors in dealing with patients/families and co-workers, concern about medical malpractice, and fatigue.

Conclusions: Early-career EPs in Japan have a high prevalence of chronic insomnia and sleep-aid use. Long working hours and stress were associated with chronic insomnia, while male gender, unmarried status, and stress were associated with the use of sleep aids.
Impact of Ultrasonography on Chest Compression Fraction and Survival in Patients with Out-of-hospital Cardiac Arrest
Authors: Lien Wan-Ching , Chong Kah-Meng , Chang Chih-Heng , Cheng Su-Fen , Chang Wei-Tien , Ma Matthew , Chen Wen-Jone
Published: March 2023

Introduction: Whether ultrasonography (US) contributes to delays in chest compressions and hence a negative impact on survival is uncertain. In this study we aimed to investigate the impact of US on chest compression fraction (CCF) and patient survival.

Methods: We retrospectively analyzed video recordings of the resuscitation process in a convenience sample of adult patients with non-traumatic, out-of-hospital cardiac arrest. Patients receiving US once or more during resuscitation were categorized as the US group, while the patients who did not receive US were categorized as the non-US group. The primary outcome was CCF, and the secondary outcomes were the rates of return of spontaneous circulation (ROSC), survival to admission and discharge, and survival to discharge with a favorable neurological outcome between the two groups. We also evaluated the individual pause duration and the percentage of prolonged pauses associated with US.

Results: A total of 236 patients with 3,386 pauses were included. Of these patients, 190 received US and 284 pauses were related to US. Longer resuscitation duration was observed in the US group (median, 30.3 vs 9.7 minutes, P<.001). The US group had comparable CCF (93.0% vs 94.3%, P=0.29) with the non-US group. Although the non-US group had a better rate of ROSC (36% vs 52%, P=0.04), the rates of survival to admission (36% vs 48%, P=0.13), survival to discharge (11% vs 15%, P=0.37), and survival with favorable neurological outcome (5% vs 9%, P=0.23) did not differ between the two groups. The pause duration of pulse checks with US was longer than pulse checks alone (median, 8 vs 6 seconds, P=0.02). The percentage of prolonged pauses was similar between the two groups (16% vs 14%, P=0.49).

Conclusion: When compared to the non-ultrasound group, patients receiving US had
comparable chest compression fractions and rates of survival to admission and discharge, and survival to discharge with a favorable neurological outcome. The individual pause was lengthened related to US. However, patients without US had a shorter resuscitation duration and a better rate of ROSC. The trend toward poorer results in the US group was possibly due to confounding variables and nonprobability sampling. It should be better investigated in further randomized studies.
Response to “Comments on Economic Evaluation of Ultrasound-guided Central Venous Catheter Confirmation vs Chest Radiography in Critically Ill Patients: A Labor Cost Model”
Authors: Ablordeppey Enyo , Koenig Adam , Barker Abigail , Hernandez Emily , Simkovich Suzanne , Krings James , Brown Derek , Griffey Richard
Published: March 2023

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NGHIÊN CỨU HOẠT TÍNH KHÁNG OXY HÓA TRÊN MỘT SỐ MÔ HÌNH IN VITRO CỦA DƯỢC LIỆU BÌM BỊP CLINACANTHUS NUTANS (BURM. F.) LINDAU, ACANTHACEAE
Authors: Nguyễn Thị Trang Đài , Cao Nguyễn Ngọc Ân , Lê Thị Thanh Yến
Published: March 2023

Đặt vấn đề: Dược liệu Bìm bịp từ lâu được sử dụng trong dân gian để làm thuốc kháng oxy hóa, kháng viêm, thấp khớp, bệnh gút, giảm đau. Mục tiêu nghiên cứu: Xác định hoạt tính kháng oxy hóa các cao toàn phần và cao phân đoạn của Bìm bịp trên một số mô hình in vitro mô hình DPPH, thử nghiệm FRAP. Đối tượng và phương pháp nghiên cứu: Dược liệu Bìm bịp được thu hái tại Núi Cấm – An Giang, tiến hành chiết xuất bộ phận dùng bằng cồn 96%, chiết phân bố lỏnglỏng cao cồn với các dung môi có độ phân cực tăng dần dichloromethan, ethyl acetat, và nước thu được các cao phân đoạn, sắc ký cột chân không cao phân đoạn thu được phân đoạn đơn giản. Thử tác dụng kháng oxy hóa trên các cao bộ phận dùng và các cao phân đoạn trên mô hình thử khả năng loại gốc tự do DPPH và mô hình khử sắt FRAP. Kết quả: Thử tác dụng kháng oxy hóa các bộ phận dùng của dược liệu Bìm bịp cho thấy cao thân có tác dụng mạnh nhất. Chiết phân bố lỏng-lỏng cao thân với các dung môi khác nhau thu được các cao phân đoạn dichloromethan, ethyl acetat và nước, kết quả thử kháng oxy hóa cao ethyl acetat có tác dụng mạnh, sắc ký cột chân không cao ethyl acetat thu được 4 phân đoạn, thử tác dụng kháng oxy hóa trên 4 phân đoạn. Kết luận: Từ kết quả nghiên cứu đã cung cấp dữ liệu về hoạt tính kháng oxy hóa của Bìm bịp, góp phần quan trọng cho cơ sở lựa chọn sử dụng dược liệu này một cách hợp lý, an toàn và phát triển nghiên cứu thành phần hóa học của Bìm bịp theo định hướng tác dụng sinh học.
NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG VÀ HÌNH ẢNH CỘNG HƯỞNG TỪ Ở BỆNH NHÂN THOÁI HÓA CỘT SỐNG CỔ CÓ CHÈN ÉP THẦN KINH TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ NĂM 2020 – 2022
Authors: Đào Quốc Toàn , Nguyễn Vũ Đằng , Nguyễn Hoàng Thuấn , Tô Anh Quân , Nguyễn Vương , Trần Hùng Quốc
Published: March 2023

Đặt vấn đề: Thoái hóa cột sống cổ là bệnh lý mạn tính ngày càng phổ biến trong cộng đồng. Do đặc điểm giải phẫu của cột sống cổ có liên quan với cả tủy sống và rễ thần kinh, nên nếu không được phát hiện và điều trị sớm có thể gây ra nhiều biến chứng nguy hiểm. Cộng hưởng từ (MRI) là phương pháp chẩn đoán hình ảnh hữu hiệu giúp phát hiện sớm bệnh lý, từ đó có hướng điều trị và dự phòng tránh những tổn thương tiến triển không hồi phục. Mục tiêu nghiên cứu: Mô tả đặc điểm lâm sàng, hình ảnh cộng hưởng từ và mối liên quan giữa đặc điểm lâm sàng ở bệnh nhân thoái hóa cột sống cổ có chèn ép rễ thần kinh hoặc tủy sống với hình ảnh cộng hưởng từ ở bệnh nhân thoái hóa cột sống cổ có hẹp lỗ liên hợp hoặc hẹp ống ống tại Bệnh viện Trường Đại học Y Dược Cần Thơ. Đối tượng và phương pháp nghiên cứu: Mô tả cắt ngang, tiến cứu trên 101 bệnh nhân đến khám tại Bệnh viện Trường Đại học Y Dược Cần Thơ được khám lâm sàng và chụp MRI có biểu hiện chèn ép thần kinh cổ năm 2020 - 2022. Kết quả: Độ tuổi trung bình là 48,48 ± 11,4. Đau cổ và rối loạn cảm giác kiểu rễ là triệu chứng hay gặp nhất. MRI ghi nhận: Vị trí thoát vị nhiều nhất ở C5-C6 (35%). Mức độ hẹp lỗ liên hợp theo Park độ 0 chiếm tỷ lệ cao nhất (31,7%); Mức độ hẹp ống sống cổ theo Kang độ 2 chiếm tỷ lệ cao nhất (40,6%). Kết luận: Có mối tương quan giữa mức độ chèn ép rễ thần kinh trên lâm sàng và mức độ chèn ép rễ thần kinh trên MRI. Có mối tương quan giữa mức độ tổn thương tủy trên lâm sàng và mức độ hẹp ống sống trên MRI.