bluuebunny/crossref_metadata_2025 huggingface dataset:
A Comprehensive Analysis of the Gravitational Wave Events with the Stacked Hilbert–Huang Transform: From Compact Binary Coalescence to Supernova
Authors: Hu Chin-Ping , Lin Lupin Chun-Che , Pan Kuo-Chuan , Li Kwan-Lok , Yen Chien-Chang , Kong Albert K. H. , Hui C. Y.
Published: August 2022

We analyze the gravitational wave signals with a model-independent time-frequency analysis, which is improved from the Hilbert–Huang transform (HHT) and optimized for characterizing the frequency variability on the time-frequency map. Instead of the regular HHT algorithm, i.e., obtaining intrinsic mode functions with ensemble empirical mode decomposition and yielding the instantaneous frequencies, we propose an alternative algorithm that operates the ensemble mean on the time-frequency map. We systematically analyze the known gravitational wave events of the compact binary coalescence observed in the first gravitational-wave transient catalog, and in the simulated gravitational wave signals from core-collapse supernovae (CCSNe) with our method. The time-frequency maps of the binary black hole coalescence cases show much more detail compared to those wavelet spectra. Moreover, the oscillation in the instantaneous frequency caused by mode-mixing could be reduced with our algorithm. For the CCSNe data, the oscillation from the proto-neutron star and the radiation from the standing accretion shock instability can be precisely determined with the HHT in great detail. More importantly, the initial stage of different modes of oscillations can be clearly separated. These results provide new hints for further establishment of the detecting algorithm and new probes to investigate the underlying physical mechanisms.
Modeling the Gamma-Ray Burst Jet Properties with 3D General Relativistic Simulations of Magnetically Arrested Accretion Flows
Authors: James Bestin , Janiuk Agnieszka , Nouri Fatemeh Hossein
Published: August 2022

We investigate the dependence of the gamma-ray burst (GRB) jet structure and its evolution on the properties of the accreting torus in the central engine. Our models numerically evolve the accretion disk around a Kerr black hole using three-dimensional general relativistic magnetohydrodynamic simulations. We use two different analytical hydrodynamical models of the accretion disk, based on the Fishbone–Moncrief and Chakrabarti solutions, as our initial states for the structure of the collapsar disk and the remnant after a binary neutron star (BNS) merger, respectively. We impose poloidal magnetic fields of two different geometries upon the initial stable solutions. We study the formation and evolution of the magnetically arrested disk state and its effect on the properties of the emitted jet. The jets produced in our models are structured and have a relatively hollow core and reach higher Lorentz factors at an angle ≳9° from the axis. The jet in our short GRB model has an opening angle of up to ∼25° while our long GRB engine produces a narrower jet, of up to ∼11°. We also study the time variability of the jets and provide an estimate of the minimum variability timescale in our models. The application of our models to the GRB jets in the BNS postmerger system and to the ultrarelativistic jets launched from collapsing stars are briefly discussed.
Timing Properties of the X-Ray Accreting Pulsar 1A 0535+262 Studied with Insight-HXMT
Authors: Wang P. J. , Kong L. D. , Zhang S. , Doroshenko V. , Santangelo A. , Ji L. , Yorgancioglu E. S. , Chen Y. P. , Zhang S. N. , Qu J. L. , Ge M. Y. , Li J. , Chang Z. , Tao L. , Peng J. Q. , Shui Q. C.
Published: August 2022

We report results on the timing analysis of the 2020 giant outburst of 1A 0535+262, using broadband data from Insight-HXMT. The analysis of the pulse profile evolution from the subcritical-luminosity to the supercritical-luminosity regime is presented for the first time. We found that the observed pulse profile exhibits a complex dependence on both energy and luminosity. A dip structure at the energy of the cyclotron resonant scattering features is found for the first time in the pulse fraction–energy relation of 1A 0535+262, when the outburst evolves in a luminosity range from 4.8 × 1037 to 1.0 × 1038 erg s−1. The observed structure is luminosity dependent and appears around the source critical luminosity (∼6.7 × 1037 erg s−1).
GRB 201104A: A “Repetitive” Short Gamma-Ray Burst?
Authors: Wang Yun , Jiang Lu-Yao , Ren Jia
Published: August 2022

Gamma-ray bursts (GRBs) are divided into short gamma-ray bursts (SGRBs) and long gamma-ray bursts (LGRBs) based on the bimodal distribution of their durations. LGRBs and SGRBs are typically characterized by different statistical characteristics. Nevertheless, there are some samples that challenge such a framework, such as GRB 060614, a long-duration burst with short-burst characteristics. Furthermore, GRBs are generally considered to be an event with no periodic or repetitive behavior, since the progenitors usually undergo destructive events, such as massive explosions or binary compact star mergers. In this work, we investigated Fermi data for possible quasiperiodic oscillations and repetitive behaviors of GRBs using timing analysis methods and report a special event GRB 201104A, which is a long-duration burst with the characteristics of an SGRB, and it exhibits a “repetitive” behavior. We propose that such a situation may arise from lensed SGRBs and attempt to verify it by Bayesian inference. In addition, we extend the spectral analysis to Bayesian inference. In spite of the existence of at least two distinct time periods with a nearly identical spectrum, there is no strong evidence that they result from a lensing GRB. Taking the gravitational-lensing scenario out of consideration, a long burst would resemble a short burst in its repetitive behavior, which presents a challenge for the current classification scheme.
An Atlas of Convection in Main-sequence Stars
Authors: Jermyn Adam S. , Anders Evan H. , Lecoanet Daniel , Cantiello Matteo
Published: August 2022

Convection is ubiquitous in stars and occurs under many different conditions. Here we explore convection in main-sequence stars through two lenses: dimensionless parameters arising from stellar structure and parameters that emerge from the application of mixing length theory. We first define each quantity in terms familiar to both the 1D stellar evolution community and the hydrodynamics community. We then explore the variation of these quantities across different convection zones, different masses, and different stages of main-sequence evolution. We find immense diversity across stellar convection zones. Convection occurs in thin shells, deep envelopes, and nearly spherical cores; it can be efficient or inefficient, rotationally constrained or not, transsonic or deeply subsonic. This atlas serves as a guide for future theoretical and observational investigations by indicating which regimes of convection are active in a given star, and by describing appropriate model assumptions for numerical simulations.
Analysis of fractal fractional Lorenz type and financial chaotic systems with exponential decay kernels
Authors: Haq Ihtisham Ul , Ahmad Shabir , Saifullah Sayed , Nonlaopon Kamsing , Akgül Ali
Published: August 2022

In this work, we formulate a fractal fractional chaotic system with cubic and quadratic nonlinearities. A fractal fractional chaotic Lorenz type and financial systems are studied using the Caputo Fabrizo (CF) fractal fractional derivative. This study focuses on the characterization of the chaotic nature, and the effects of the fractal fractional-order derivative in the CF sense on the evolution and behavior of each proposed systems. The stability of the equilibrium points for the both systems are investigated using the Routh-Hurwitz criterion. The numerical scheme, which includes the discretization of the CF fractal-fractional derivative, is used to depict the phase portraits of the fractal fractional chaotic Lorenz system and the fractal fractional-order financial system. The simulation results presented in both cases include the two- and three-dimensional phase portraits to evaluate the applications of the proposed operators.
Penser le développement comme un mythe : croyances, engagements et (in)cohérences de l’engagement coopératif au Chiapas (Mexique)
Authors: Parizet Raphaëlle
Published: August 2022

Cet article se penche sur le cas d’une coopérative de développement agricole réunissant des producteurs indiens de café dans la région du Chiapas au Mexique, initiée par la mission jésuite, et le confronte à l’analyse de G. Rist qui attribue au développement une direction unique et une irréversibilité. En s’appuyant sur les travaux de P. Veyne, l’article propose au contraire un réenchantement mythique du développement : ce qui est central ici, c’est la plasticité et la complexité des régimes de croyances – applaudir la coopérative n’est pas nécessairement l’ovationner. À partir d’une analyse processuelle de l’engagement, l’article cherche à comprendre les raisons d’entrée et de maintien des agriculteurs dans la coopérative. Les croyances des coopérateurs ne sont pas toutes alignées, elles s’ajustent, se contredisent et n’ont pas besoin d’être valides pour opérer. L’irréductible externalité, l’existence de figures tutélaires et d’expériences sociales partagées s’articulent à des nécessités économiques, des chevauchements de sociabilité et de solidarité, l’ensemble faisant tenir un passé collectif marqué par des conflits, des déceptions militantes et des trajectoires individuelles d’engagement.
Lenguaje Multimodal y Códigos de Legitimación: hacia una nueva didáctica de la Filosofía Multimodal Language and Legitimation Codes: towards a new didactics of Philosophy
Authors: Dávila Manrique Verónica , Tamayo Alzate Óscar Eugenio
Published: August 2022

Este ensayo forma parte de la reflexión inicial sobre el desarrollo de la tesis doctoral en educación; un proceso formativo que ha permitido promover otras visiones de la actividad docente dentro del aula. En este sentido, y reconociendo la complejidad de la filosofía como disciplina académica a nivel universitario, se ha podido identificar los enfoques teóricos y metodológicos que se espera que contribuyan a la formación de los docentes en esta área del conocimiento. De esta forma, el contenido de este escrito pretende dar cuenta, por un lado, de los diferentes artistas reflexivos que se despliegan a lo largo de la consolidación de ambas teorías; perspectivas que son de largo alcance y que se mantienen vigentes y, en segundo lugar, muestran los caminos de desarrollo que se están desarrollando, tratando de explicar los intereses que se persiguen en torno a la comprensión de lo que, en términos explicativos, ocurre dentro de la clase. Esta propuesta trae alivio a las discusiones sobre lo que podría denominarse una nueva filosofía didáctica, a través del encuentro con autores como Kress (2013); Maton (2014), entre otros.
Mechanical Properties of Blast Furnace Slag and Rice Husk Ash with Coconut Shell as Partial Replacement of Aggregates
Authors: Vasudevan Gunalaan , Sheng Mau Sau
Published: August 2022

This research showed the application of concrete material in construction industry were highly demand which growing rapidly demonstrate the need for various types and properties of concrete to meet the diverse needs of the user. Normally, the quality of concrete with high durability properties can be generated by consideration of the composition of the materials used such as cement, sand, aggregates or water. Besides that, mix design and the way of production like mixing, transporting and pouring concrete is also the factors to get a better quality of concrete. Recently, the sustainability in construction is one of the efforts that have been practiced by developed countries to create healthier environment and to reduce the environmental impact of a building over its entire lifetime, while optimizing its economic viability and the comfort and safety of its occupants. One of the steps that can be practice is to use materials that are categorized as agricultural waste material such as palm oil fuel ash, rice husk, fly ash slag, sludge, coconut shell and etc. in concrete manufacturing. Hence, the objective of this paper is to evaluate the performance of blast furnace slag, rice husk ash and coconut shell as partial replacement of aggregates in cement. A series of test were conducted to investigate the performance of blast furnace slag, rice husk ash and coconut shell as partial replacement of aggregates in cement. The tests that are being conducted are compressive strength test, flexural strength test, rebound hammer test, ultrasonic pulse velocity test, water permeability test, sieve analysis test, water absorption test, carbonation test, alkali-silica reaction test, SEM test and shrinkage test.
Strength Properties and Toughness Indices of Hybrid Polymeric Fibre Reinforced Renewable Oil Palm Shell Concrete
Authors: Yew Ming Kun , Yew Ming Chian , Ang Bee Chin , Beh Jing Han , Lee Foo Wei
Published: August 2022

In this study, the strength properties and durability of polymeric fibre-reinforced concrete containing renewable oil palm shell (ROPS) lightweight aggregate were investigated. The effect of individual Polyvinyl Alcohol (PVA) fibre, individual Polypropylene (PP) fibre and hybrid PVA-PP fibre with various percentage of volume fraction, Vf (0, 0.3 and ‘0.25+0.05’%) on the compressive strength and toughness indices of ROPS LWC were examined. The research outcomes show that compressive strength of ROPS lightweight concrete strengthened with individual PVA fibre or PP fibre enhanced with the increase of Vf fibre. From the results, toughness indices increased significantly by 38.3% compared to control mix. Furthermore, the hybrid ‘PVA0.25/PP0.05’ had revealed the optimum results as associated to other mixes. Thus, the outcomes of this paper showed that the blend of both PVA and PP polymeric fibre could potentially be utilized in concrete industry.
Opportunity Utilization Tailings Waste as Fine Aggregate Material in Asphalt Mixture Performance to Support Sustainable Development Goals (SDGs): A Preliminary Study
Authors: Lapian Franky E.P. , Tumpu M.
Published: August 2022

Currently, road pavement construction in Indonesia utilized standard materials derived from natural materials such as coarse and fine aggregate. The used of these materials, especially sand used as fine aggregate, will interfere with environmental sustainability, in addition in several locations in Indonesia, these materials were very difficult to obtain or the quality was not in accordanced with the National Indonesian Standard (Bina Marga requirements). In several locations in Indonesia, such as in Timika (Papua) there was material that has the size of sand, included waste from PT Freeport as a waste material from the gold and copper ore mining processed. This material was known as tailings. Currently, tailings waste has reached 223,100 tons per day. This condition was certainly very disturbed to the environment due to the large deposits and so far it has not been optimally utilized for road pavement construction. By conducted an assessment of the properties of this material, both the tailings themselves and the asphalt mixture that has used tailings as its constituent material that functions as a road pavement layer, will provide answers to the benefits of tailings in road pavement construction. The results showed that the asphalt mixture using tailings waste can be used as asphalt mixture material in the LPPA mix type. The used of tailings as one of the asphalt mixture materials can also supported the acceleration of sustainable development carried out by Indonesia to support global actions carried out based on the Sustainable Development Goals (SDGs) to be achieved in 2030.
Cycle integrals of the $j$-function on Markov geodesics
Authors: Bengoechea Paloma
Published: August 2022

We give asymptotic upper and lower bounds for the real and imaginary parts of cycle integrals of the classical modular

j

-function along geodesics that correspond to Markov irrationalities.
Computability Theory
Authors: Brattka Vasco , Greenberg Noam , Kalimullin Iskander , Soskova Mariya
Published: August 2022

Over the last decade computability theory has seen many new and fascinating developments that have linked the subject much closer to other mathematical disciplines inside and outside of logic. This includes, for instance, work on enumeration degrees that has revealed deep and surprising relations to general topology, the work on algorithmic randomness that is closely tied to symbolic dynamics and geometric measure theory. Inside logic there are connections to model theory, set theory, effective descriptive set theory, computable analysis and reverse mathematics. In some of these cases the bridges to seemingly distant mathematical fields have yielded completely new proofs or even solutions of open problems in the respective fields. Thus, over the last decade, computability theory has formed vibrant and beneficial interactions with other mathematical fields.

The goal of this workshop was to bring together researchers representing different aspects of computability theory to discuss recent advances, and to stimulate future work.
Classical Algebraic Geometry
Authors: Debarre Olivier , Eisenbud David , Farkas Gavril , Vakil Ravi
Published: August 2022

Progress in algebraic geometry often comes through the introduction of new tools and ideas to tackle the classical problems in the development of the field. Examples include new invariants that capture some aspect of geometry in a novel way, such as the derived category, and the extension of the class of geometric objects considered to allow constructions not previously possible, such as the transition from varieties to schemes or from schemes to stacks. Many famous old problems and outstanding conjectures have been resolved in this way over the last 50 years. While the new theories are sometimes studied for their own sake, they are in the end best understood in the context of the classical questions they illuminate. The goal of the workshop was to study new developments in algebraic geometry, with a view toward their application to the classical problems.
The Role of Rural Women’s Occupations on Electrification and Use of Electric Stoves for Households in Busega District, Tanzania
Authors: Andrew Ngusa Deborah
Published: August 2022

The paper addressed occupations as socio-economic qualities that determine rural women’s capabilities to install and use electric stoves in their households. The study applied the cross-sectional design through conducting a household survey. The study sample size included 210 rural women and seventeen key informants. Qualitative data was analysed through content analysis while the quantitative data was analysed by computing descriptive statistics, cross tabulation and chi-square test. The study established that majority of rural women were interested in installing electricity and using electric cookers in their households. However, households without electricity lacked income for paying the required charges to get services. Men controlled installation and usage of electric cookers in households as they were the main bread winners while women lacked income to meet the required charges. As a result, rural women were negatively affected by the burden of firewood collection and cooking that led into deforestation in the area. The study recommends that sensitization on the installation and use of electric cookers should be done to rural women to increase their awareness on the benefits of adopting them. In addition, development stakeholders should support rural women by increasing their capacity for conducting income generation activities to get higher profits.
Screen Time and Health Disturbances during the Covid-19 Pandemic: A Case of University Students in Zimbabwe
Authors: Nhatuve Diocleciano , Wayne Madzokere Amanda
Published: August 2022

This study sought to establish health disturbances experienced by university students due to prolonged screen use during the covid-19 Pandemic in Zimbabwe. It employed the descriptive design under the quantitative approach. The study involved students from two universities in Zimbabwe, and it used a random sampling technique. A total of 128 students participated completing a survey. Data collection was conducted through a survey with a one closed-ended question seeking to identify health challenges experienced by students due to prolonged use of screens. Results were presented in percentages through graphs. The study concludes that headaches, tiredness and difficulties to sleep were experienced by students as a consequence of prolonged screen time. Furthermore, students experienced different psychological disturbances including stress and depression, inattention (difficulties to concentrate), anxiety and low self-esteem as a consequence of prolonged screen time. Finally, sight loss, tearing eyes, eye irritation, eye redness, eye swelling and dry eye disease were experienced by respondents.  Based on the conclusions, the study recommends that students and all users of digital technologies for different purposes should control the time they spend on the screen and visit doctors whenever they have abnormal experience in their eyes for further guidance. The study further recommends that learning institution should come up with measures to reduce the time individuals spend on the screen by providing alternative study options that may reduce the time spent on screens for learning.
Education and the Scourge of Child Marriages in Chegutu Urban and Peri-urban Clusters of Zimbabwe
Authors: Samkange Wellington
Published: August 2022

This study sought to establish factors that contributed to child marriages in two Chegutu urban and peri-urban clusters of Zimbabwe. It used the mixed research method and the descriptive survey design. Five primary schools and five secondary schools were purposively sampled out of a total of forty schools in the clusters. Two hundred stakeholders were randomly selected from a population of one thousand five hundred. A questionnaire and interviews were used to collect data from selected school heads, teachers, parents, school development committee members and community leaders. The study established that poverty, socio-economic background, society’s perception of marriage, cultural values, lack of information and religion remain major drivers of child marriages. At the same time, the school curriculum did not fully address the issues of children’s rights and health education. The study recommends a radical approach to ending child marriages which may include banning religious sects and traditional practices that promote child marriages.  It further recommends an improvement of the school curriculum, for it to take the issue of children’s rights and health education seriously.
America or India: Identifying a Suitable Off-Grid Rural Electrification Model for Nigeria.
Authors: Herbert Eti Best
Published: August 2022

Most Nigerian living in the rural areas lack access to electricity due to lack of connectivity to the national grid network. The national grid expansion strategy to rural areas has not yielded much result due to financing and centralised approach. Off-grid electricity is considered more suitable for rapid electrification of rural areas. This paper examined the American and Indian approach to rural electrification and derived suitable lessons for Nigeria. While America ensured a robust national grid network to service rural areas, India adopted the renewable energy based off-grid options, thereby becoming the fastest developing country in rural electrification.

Keywords: Rural Electrification; Off-grid, National Grid; Renewable Energy; Financing; Decentralisation
Chrysoeriol alleviated inflammation in infantile pneumonia by inhibiting PI3K/AKT/mTOR signaling pathway
Authors: Wang Yan , Hong Qiuyue
Published: August 2022

Purpose: To assess the therapeutic effects of chrysoeriol (CHE) on pediatric pneumonia and determine the mechanism of action.

Methods: The role of chrysoeriol was investigated in a human lung fibroblasts (HFL1) cell model of pneumonia. The effects of lipopolysaccharide (LPS) and CHE on cell viability and apoptosis were determined by CCK-8 kit and flow cytometry, respectively, while oxidative stress was determined by evaluating the levels of superoxide dismutase (SOD), glutathione, r-glutamyl cysteine +glycine (GSH)- px, myeloperoxidase (MPO) and malondialdehyde (MDA). Inflammatory response was assessed by determining IL-1β, TNF-α, IL-18 and IL-10 levels using enzyme-linked immunosorbent assay (ELISA). The mechanisms of action of CHE were evaluated by immunoblot assays.

Results: Chrysoeriol increased the viability of LPS-induced pneumonia cells (p < 0.001) but decreased cell apoptosis (p < 0.001). Furthermore, chrysoeriol reduced oxidative stress and inflammation in LPSinduced pneumonia cells, and suppressed the activation of PI3K/AKT/mTOR pathway.

Conclusion: Chrysoeriol alleviates inflammation of infantile pneumonia by inhibiting PI3K/ AKT /mTOR signaling pathway. Thus, CHE is a potential drug for the management of pneumonia.

Keywords: Chrysoeriol; Pneumonia; Cell viability; Oxidative stress; PI3K/AKT/mTOR pathway
IRF2BP2 attenuates gestational diabetes mellitus by activating AMPK signaling
Authors: Zhang Shuyun , Wang Yunjie , Zhou Ling , Yu Ziyang , Gao Aihua
Published: August 2022

Purpose: To investigate the role of interferon regulatory factor 2 binding protein 2 (IRF2BP2) in gestational diabetes mellitus (GDM).

Methods: Mice were injected intraperitoneally with streptozotocin to establish a model of GDM and then subjected to intraperitoneal glucose tolerance test (IPGTT) and intraperitoneal insulin tolerance test (IPITT) to determine glucose and insulin tolerances. Lipid metabolism was evaluated by enzyme-linked immunosorbent assay (ELISA). The histomorphology of pancreatic islets was assessed by hematoxylin and eosin staining.

Results: IRF2BP2 was downregulated in pancreatic tissues of mice with GDM (p < 0.001). Mice in GDM group showed higher blood glucose levels than those in normal pregnancy group. However, overexpression of IRF2BP2 reduced glucose and insulin levels in mice with GDM. Overexpression of IRF2BP2 increased the level of high-density lipoprotein (HDL) and reduced triglyceride (TG), total cholesterol (TC), and low-density lipoprotein (LDL) levels in mice with GDM (p < 0.001). The histopathological changes in the islets of mice with GDM were also ameliorated by overexpression of IRF2BP2. Overexpression of IRF2BP2 reduced IL-6, IL-1β, and TNF-α levels and increased protein expression of p-AMPK in mice with GDM.

Conclusion: IRF2BP2 ameliorates the outcomes of GDM and suppressed inflammation in mice with GDM through activation of AMPK signaling. Thus, IRF2BP2 is a potential therapeutic strategy for the management of GDM.

Keywords: IRF2BP2; inflammation; gestational diabetes mellitus; AMPK; mice; insulin tolerance
Pharmacy students’ perceptions and attitudes towards experiential training in Jordan and United Kingdom
Authors: Hammad Alaa M , Al-Qerem Walid A , Sunoqrot Suhair Z , Amawi Haneen A , Arabyat Rasha M , Ling Jonathan , Robertshaw Carlie
Published: August 2022

Purpose: To examine the quality of pharmaceutical experiential training by developing an experiential training survey.

Methods: An online survey was placed on E-learning platforms in Jordan and UK to develop a validated instrument that can assess pharmacy students' perceptions of the experiential program implemented in their curricula.

Results: A total of 377 students from Jordan (250 students) and the UK (127 students) completed the survey. Principal component analysis was used to conduct exploratory factor analysis and to assess the factor structure for the data. A two-factor model was applied to the data obtained from the students. These factors included students’ feelings toward experiential training (Perceiver Feelings; PF) and their ability to conduct a full Pharmaceutical Care Plan (PCP). Students from both Jordan and the UK showed a higher satisfaction PF score toward the experiential training program compared to PCP. Being female and not having prior practice experience led to significantly lower PCP scores compared to males and having a prior practice experience, respectively.

Conclusion: The availability of a validated questionnaire will help in investigating the effectiveness of experiential training courses.

Keywords: Experiential training; Factor Analysis; Survey development; Pharmacy
Bauerenol inhibits proliferation, migration and invasion of retinoblastoma cells via induction of apoptosis, autophagy and cell cycle arrest
Authors: Chen Yiyi , Peng Jianjun , Cao Si
Published: August 2022

Purpose: To determine the anticancer effects of bauerenol on human retinoblastoma cells.

Methods: The effect of bauerenol on cell proliferation was evaluated using 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide (MTT) assay, while cancer cell migration and invasion were determined by Transwell assay. Apoptosis of retinoblastoma cells was assessed by Annexin VFITC/PI staining procedure. Autophagy was evaluated using TEM, while cell cycle was studied by flow cytometry.

Results: Bauerenol significantly inhibited the proliferation of retinoblastoma cells, with a half-maximal inhibitory concentration (IC50) of 10 μM (p < 0.05). However, bauerenol exhibited a comparatively lower antiproliferative effect on normal paediatric retina cells, with a higher IC50 of 100 μM. Annexin V/PI staining results revealed that the antiproliferative effect of bauerenol was due to apoptotic cell death. The proportion of apoptotic SORB-50 cells increased from about 4 % in control to about 19 % on exposure to 20 μM bauerenol. Western blot assay showed marked up-regulation of LC3B II protein, indicating autophagy. Cell cycle analysis showed that the arrest of SO-RB50 cells at the G2/M phase of the cell cycle markedly contributed to the antiproliferative effects of bauerenol. Moreover, the migration and invasion of SO-RB50 cells were suppressed by bauerenol (p < 0.05).

Conclusion: These results indicate that bauerenol suppresses the growth of retinoblastoma cells. Therefore, it may be a beneficial lead molecule for the development of a suitable agent for the treatment of retinoblastoma.

Keywords: Retinoblastoma; triterpenoid; anticancer; apoptosis; autophagy; migration; invasion; metastasis
Bir Pazar Günü (1930) Filmi Üzerinden Kracauer’in Bulunmuş Öykü Kavramına Bakış
Authors: DEMOĞLU Meliha Elif
Published: August 2022

Gerçekçi kuramcılardan Siegfried Kracauer, sinemaya toplumbilimsel açıdan yaklaşan ilk kuramcılardandır. Caligari’den Hitler’e (1947, 2011a) eserinde Weimar dönemi sinemasını incelemiş ve Nazi Partisi iktidara gelmeden önce filmlerde faşist eğilimlerin simgelerinin görülebileceğini dile getirmiştir. Sinemanın toplumu gerçekçi biçimde yansıtması gerektiğini ifade eden Kracauer, fiziksel gerçekliğin sinemada ‘bulunmuş öykü’ (found story) ile yakalanabileceğini belirtmiştir. Bulunmuş öyküde, hayatın doğal akışının yakalanması, belirsizlik gibi unsurlar önem kazanmaktadır. Bulunmuş öykü, sinemada gerçekliğe ulaşmada işlevsel bir biçim olmasına rağmen toplumun gerçekliğini yansıtmada tek başına yeterli değildir. Naziler iktidara gelmeden hemen önceki yılların Berlin’ini belgeleyen, sıradan insanların kendi gündelik yaşamlarını canlandırdığı Bir Pazar Günü (1930, R. Siodmak, E. Ulmer) filmi, Weimar dönemi sineması içerisinde çekim koşulları, belgesel ve kurmaca arasında kurduğu köprü açısından ayrıksı bir yerde dururken, filmde bulunmuş öykü yapısı görülmektedir. Aynı zamanda, Kracauer’in Caligari’den Hitler’e (2011a) kitabında eleştirdiği Weimar dönemi sinemasının ürünü olmasıyla, eleştirel bir okumaya imkân tanımaktadır. Bu çalışmada, bulunmuş öykü yapısını, sinema ve toplum ilişkisi bağlamında incelemek amacıyla Bir Pazar Günü filmi toplumbilimsel yöntemle analiz edilmiştir. Kracauer’in Caligari’den Hitler’e (2011a) kitabında eleştirdiği film, yazarın Film Teorisi (2015) kitabında ideal film biçimi olarak öne sürdüğü bulunmuş öykü yapısını taşısa da, bu yapının toplumun, dönemin gerçeklerini aktarmada tek başına yeterli olmadığı ortaya koyulmuştur.
Diegesis - Mimesis
Authors: HALLIWELL Stephen
Published: August 2022

Bu makale, Stephen Halliwell’in The Living Handbook of Narratology’de yer alan 2014 tarihli “Diegesis-Mimesis” isimli makalesinin Türkçe çevirisidir. Anlatıbilim alanının anlatmak/göstermek (telling/ showing) olarak karşıladığı diegesis/mimesis terimleri ilk kez Platon’un Devlet’indeki bir pasajda bir arada kullanılmıştır. Sonrasında Aristoteles, Poetika adlı eserinde terimleri kendi bağlamınca yeniden kullanır; fakat bu kullanım kimi noktalarda Platoncu izler taşıyor olmakla birlikte, kimi bakımlardan münferit yeni bağlamlarıyla Devlet’deki kullanımdan ayrışır. Günümüzde bu dikotomi, anlatıbilim alanının tayin ettiği dar karşılıklarıyla dolayıma girmiştir. Öte yandan Platon’un Devlet’i referans alındığında Sokrates tarafından çizilen temel ayrımın standart modern kullanımdaki gibi tümüyle “göstermek” ve “anlatmak” arasında olmadığı görülmektedir. Dahası, Antik Çağ’daki bu ilk kullanımlarından itibaren, eleştirel düzlemde kategorik bir çift olarak terimlerin uzun ve kimi zaman ziyadesiyle karmaşık kullanımlarının tarihi, günümüze kadar uzanmaktadır. Bu makalede Stephen Halliwell, söz konusu bu karmaşayı, Sokrates’in görüşlerinin aktarıldığı/yorumlandığı Platon’un Devlet’ine ve Aristoteles’in Poetika’sına odaklanarak ortaya koymakta, terimlerin Orta Çağ ve Rönesans’taki kullanımlarına değinmekte, modern anlatıbiliminin indirgemeci kategorizasyonu kaynaklı açmazlara dikkat çekmekte, ve son olarak, konu üzerine çalışmak isteyen araştırmacılara alanda gördüğü boşlukları işaret etmektedir.
FAMILY FUNCTIONALITY IN CONTEXT OF SYSTEMIC FAMILY THERAPY AND FAMILY CONSTELLATIONS METHOD
Authors: Matejević Marina , Petrović Jelena
Published: August 2022

This paper analyses family functioning from the perspectives of family systemic therapy and family constellations method. In explaining family functionality Olson (2000) describes this phenomenon from the point of view of present situation, analyzing current patterns of family functioning, whereas Hellinger (2014) describes it from the perspective of transgenerational transmission. Both approaches emphasize the importance of differentiation from the family of origin. They find the problem of pathological loyalty to the family of origin important for understanding the dysfunctional patterns of family functioning, although they analyze it from different perspectives. Both methods can fully contribute to the healing of family and the individual: family constellations by successfully resolving the problems in the unconscious sphere, and systemic approach by helping development of awareness and understanding of family functioning. Systemic family therapy and family constellations can represent a good synthesis of therapeutic methods that, when used together, can significantly contribute to the harmonious family functioning.
Effectiveness of Various Types of LASER Therapy during In-Office Teeth Bleaching: A Systematic Review
Authors:   Under Graduate Student (Bachelor of Dental Surgery), Department of Public Health Dentistry, SRM Dental College and Hospital, Ramapuram, Chennai, India., Infantina Vincy
Published: August 2022

Background: Vital bleaching is most requested cosmetic dental procedure asked by patients who seek pleasing smile. Laser helps to reduce the stain and helps in teeth whitening. Aim: To investigate the effect of laser therapy induced by teeth bleaching. Methodology: A Literature review was performed using PubMed, Medline, PMC, Grey literature, Cochrane, Prospero, Wiley online library using MeSH term laser and teeth bleaching. Of a total 1658 appeared from various sources; all articles were screened and 14 were related to the research question and 5 were selected for the study. This review was reported according to PRISMA guidelines. Result: In the five studies of our systematic review shows that laser used in the case of teeth bleaching with higher concentration of hydrogen peroxide produced better result and comparatively lesser sensitivity than any other bleaching agents or lesser concentration of hydrogen peroxide. Conclusion: Clinical trials suggests that laser used in bleaching the tooth has better efficacy on tooth surface which resulted in lesser sensitivity and better tooth color, at the same time effectiveness of the treatment is same as that of the normal procedure.
An Unloving Parenthood: Understanding Narcissistic Parenting through Japanese Pop Culture
Authors:   Program Studi Kajian Wilayah Jepang, Sekolah Kajian Stratejik dan Global, Universitas Indonesia  Jl. Salemba Raya No.4, RW.5, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta 10430, Goenawan Teresa Chiquita
Published: August 2022

This research discusses narcissistic parenting represented in the comic Fruits Basket by Natsuki Takaya. Narcissistic parenting is a parenting style affected by a parent’s narcissism. This parenting style doesn’t offer enough space for a child to be themselves. A parent’s narcissism causes the parent to inflict physical and emotional abuse against children. This research is a descriptive qualitative research based on the concept of narcissistic parenting written in The Narcissistic Family: Diagnosis and Treatment by Stephanie Donaldson-Pressman and Robert M. Pressman. This research discusses the effect of narcissistic parenting found in children through the relationship between characters in the text. This research found out that children who survive narcissistic parenting might develop internal problems such as lack of emotional stability, lack of confidence and self-esteem, fragile sense of identity, inappropriate desire to be the center of attention, lack of empathy, grandiosity, and tendency to justify one’s wrongdoing and commit blame-shifting.
Kualitas Pelayanan Publik Pada Dinas Kependudukan Dan Catatan Sipil Kabupaten Dompu
Authors: Novita Anggun Putri , Wardani Rosyia , Helmida Baiq Ertin
Published: August 2022

This study aims to determine the quality of public services at the Department of Population and Civil Registry of Dompu Regency. The variable in this study is the single variable of Public Service Quality. The population of this study were residents of Dompu Regency aged 17 years and over who received services at the Department of Population and Civil Registry of Dompu Regency. The sample was determined by the Incidental Sampling technique with a total of 100 respondents who provided services at the Population and Civil Registry Office of Dompu Regency. Data were analyzed using SPSS. The results of this study indicate that the quality of public services at the Department of Population and Civil Registry of Dompu Regency is 70% higher than the average ideal value (accepted), in other words Ho, namely the quality of public services at the Department of Population and Civil Registry of Dompu Regency is lower 70 % (rejected). The conclusion of this research is that the quality of public services at the Department of Population and Civil Registration of Dompu Regency has met most of the expectations of the Dompu people.
Pengaruh Kualitas Pelayanan, Kinerja Petugas dan Fasilitas terhadap tingkat Kepuasan Masyarakat dalam Pelaksanaan Program Pelayanan Administrasi Terpadu Kecamatan (PATEN) di Kecamatan Aur Birugo Tigo Baleh
Authors: Febriani Dewi
Published: August 2022

This study aims to analyze the effect of service quality, officer performance and facilities on the level of satisfaction in the implementation of PATEN in Aur Birugo Tigo Baleh District, Bukittinggi City. This study uses a quantitative approach because the observed symptoms are converted into numbers that are analyzed using statistics. The author chose the sample using a saturated sampling technique because the population is relatively small. So that the sample used in this study amounted to 63 people. The purpose of this study was to determine the effect of each variable of Service Quality (X1), Officer Performance (X2) and Facilities (X3) on Community Satisfaction (Y). (X1) Service Quality and (X2) Officer Performance have a significant and positive effect on Community Satisfaction and the Facility variable (X3) has a positive but not significant effect. It can be concluded that human resources and service quality are very important to be improved in order to create satisfaction for the people who get PATEN services.

Keywords: Service Quality, Officer Performance, Facilities, Community Satisfaction, District integrated administrative services (PATEN)
Efektifitas Pelayanan Jemput Bola Kartu Identitas Anak (KIA) Dinas Kependudukan Dan Pencatatan Sipil Kota Payakumbuh
Authors: Brianda Wiko Okta , Hasan Alizar
Published: August 2022

Indonesian citizens aged 17 years and over have an Identity Card (KTP) as their iden-   tity.   Children also have their own identity cards.   The government has implemented MCH   by issuing Minister of Home Affairs Regulation Number 2 of 2016 concerning Child Identity Cards. Permendagri Number 67 of 2020, the central government sets a target in achieving  the Issuance of Child Identity Cards (KIA) for Provinces and Regencies/Cities throughout Indonesia. The targets that must be realized by Provinces and Municipalities from 2020- 2024 are: 20% in 2020, 30% in 2021, 40% in 2022, 50% in 2023, 60% in 2024. MCH Policy

in the City Payakumbuh is still not fully known by the public.  Some of the people do not  know about the existence of MCH and the benefits of MCH. For people who already know about MCH, they also have a lack of awareness to manage MCH where people think MCH         is not really needed, especially for children under 5 years old where all children’s activities are under the supervision of their parents.   So that the issuance of MCH in Payakumbuh          is still low. In addition to the lack of public knowledge about MCH, the community is also reluctant to take their children to the Population and Civil Registration Office on the grounds that the children are in school, the location of the Population and Civil Registration Office is quite far or the community lacks time to take their children so they can have a Child Identity Card ( KIA) because they work.   The purpose of this study is to describe the effectiveness      of the ball pick-up service carried out by the Population and Civil Registration Service in increasing MCH ownership and to find out the supporting factors and inhibiting factors in    the Payakumbuh City Population and Civil Registration Service. This type of research is qual- itative research

In the study,  it was found that the number of residents aged 0-17 years less than 1 day       who had a Child Identity Card (KIA) in Payakumbuh City was quite a lot and almost met       the targeted MCH ownership standards. This is sufficient to prove that the MCH services provided are adequate by implementing the Ball Pick-up program, namely direct services to various places in Payakumbuh City including the Kelurahan office,  schools and others       to provide direct services with the aim of making it easier for the community to manage  MCH. However, the services provided are still experiencing various kinds of obstacles where the ball pick-up service has not been scheduled due to an inadequate budget,  besides that  the facilities and infrastructure are still inadequate. to the center and the lack of socializa- tion specifically to the community regarding the importance of MCH so that the community considers MCH as a form of service for population administration documents that are less important so they are lazy to manage it.

Keywords : Effectiveness, Ball Pick-up Service, Child Identity Card (KIA)
Pengaruh Kualitas Pelayanan Terhadap Kepuasan Pelanggan Super Optical Padang
Authors: Novalinda Rina , Suryanta Dolly iman
Published: August 2022

This Scientific Paper discusses the Effect of Service Quality on Customer Satisfaction at Super Optical Padang. This study aims to reveal; (1) knowing the description of service quality at Super Optical, (2) knowing customer satisfaction at Super Optical Padang, (3) knowing the relationship between service quality and customer satisfaction at Super Optical Padang. This research was conducted by distributing questionnaires to customers who came to Super Optical Padang. , then the data that has been collected through the questionnaire is discussed based on the theory proposed in the literature review, and the data is presented based on the answers from the respondents who came to Super Optical Padang. Respondent samples taken were 30 respondents consisting of 11 male respondents (36.67%) and 19 female respondents (63.33%). The results of this study indicate that the variables of Service Quality and Customer Satisfaction have a correlation value of 0.502, which means that the two variables have a fairly strong relationship. Service Quality has a significant influence on Customer Satisfaction. The conclusion obtained from this study is that the influence of service quality is quite strong on customer satisfaction. And there are several dimensions of service quality that must be improved again, this is to continue to improve customer satisfaction.
Kariya Pod-Husks: A Novel Biocatalyst in Biodiesel Production
Authors:   Department of Agricultural Engineering, First Technical University, Ibadan, Nigeria, Ogundahunsi OE , Ogunsina BS ,   Department of Agricultural & Environmental Engineering, Obafemi Awolowo University, Ile Ife, Nigeria
Published: August 2022

Diverse challenges faced with the use of homogeneous catalysts in biodiesel production coupled with the interest in converting waste resources to useful products in solving occurring climatic and environmental challenges around the world have triggered research into the use of various heterogeneous catalysts. In this study, the catalytic properties of kariya pod-husks were investigated to examine their suitability in biodiesel production. Kariya podhusks were ash and calcined at 600°C for 4 h. In the morphological structure examination, the scanning electron image of calcined kariya pod-husks shows that it has a more compact microstructure with a cluster of big crystals but irregular pores which is an attribute of high catalytic potentials. The elemental composition of the calcined kariya pod-husks reveals that it contains a higher percentage weight of calcium (42%) and potassium (31%) which makes it a more suitable catalyst for biodiesel production. The developed catalyst was further used in the production of kariya biodiesel. A biodiesel yield of 94% was obtained. This study shows that calcined kariya pod-husks could catalyze biodiesel production. It also helps in proving suitable biocatalyst to solve the challenges associated with the separation of catalyst from the product stream which consequently aids in the creation of continuous chemical processes.
Multidimensional Comparative Analysis of the House Price Index in Europe Between 2021-2022 in the Aspect of Economic Security
Authors: Kozicki Bartosz , Tomaszewska Aleksandra , Jaśkiewicz Paweł , Jurgilewicz Oktawia , Przybylski Przemysław
Published: August 2022

The article presents a multidimensional comparative analysis of the impact of crude oil and liquefied petroleum gasses (LPG) prices on the housing price index in 28 European countries. Research shows that the COVID-19 pandemic and the attack of Russia on Ukraine have led to similar large fluctuations in crude oil and LPG prices. This, in turn, contributed to an increase in inflation and house price indices in the 28 analyzed European countries. Such an increase was driven by higher total construction costs, including higher prices for materials, energy and charges for building services. Housing prices in respective European countries vary. The study examines the dynamics of their changes and compares them with the use of ranking.