bluuebunny/crossref_metadata_2025 huggingface dataset:
Volatile Organic Compound Vapour Measurements Using a Localised Surface Plasmon Resonance Optical Fibre Sensor Decorated with a Metal-Organic Framework
Authors: He Chenyang , Liu Liangliang , Korposh Sergiy , Correia Ricardo , Morgan Stephen P.
Published: February 2021

A tip-based fibreoptic localised surface plasmon resonance (LSPR) sensor is reported for the sensing of volatile organic compounds (VOCs). The sensor is developed by coating the tip of a multi-mode optical fibre with gold nanoparticles (size: 40 nm) via a chemisorption process and further functionalisation with the HKUST-1 metal–organic framework (MOF) via a layer-by-layer process. Sensors coated with different cycles of MOFs (40, 80 and 120) corresponding to different crystallisation processes are reported. There is no measurable response to all tested volatile organic compounds (acetone, ethanol and methanol) in the sensor with 40 coating cycles. However, sensors with 80 and 120 coating cycles show a significant redshift of resonance wavelength (up to ~9 nm) to all tested volatile organic compounds as a result of an increase in the local refractive index induced by VOC capture into the HKUST-1 thin film. Sensors gradually saturate as VOC concentration increases (up to 3.41%, 4.30% and 6.18% in acetone, ethanol and methanol measurement, respectively) and show a fully reversible response when the concentration decreases. The sensor with the thickest film exhibits slightly higher sensitivity than the sensor with a thinner film. The sensitivity of the 120-cycle-coated MOF sensor is 13.7 nm/% (R2 = 0.951) with a limit of detection (LoD) of 0.005% in the measurement of acetone, 15.5 nm/% (R2 = 0.996) with an LoD of 0.003% in the measurement of ethanol and 6.7 nm/% (R2 = 0.998) with an LoD of 0.011% in the measurement of methanol. The response and recovery times were calculated as 9.35 and 3.85 min for acetone; 5.35 and 2.12 min for ethanol; and 2.39 and 1.44 min for methanol. The humidity and temperature crosstalk of 120-cycle-coated MOF was measured as 0.5 ± 0.2 nm and 0.5 ± 0.1 nm in the humidity range of 50–75% relative humidity (RH) and temperature range of 20–25 °C, respectively.
Does Free Route Implementation Influence Air Traffic Management System? Case Study in Poland
Authors: Dudek Ewa , Krzykowska-Piotrowska Karolina
Published: February 2021

The issue addressed in this publication concerns new Air Traffic Management (ATM) functionality, identified in the Commission Implementing Regulation (EU) No 716/2014, known as Flexible Airspace Management and Free Route (FRA). The authors pose a question—does free route implementation influence air transport safety? What can be done to maintain the current level of safety and still implement modern solutions? To achieve the aim of this paper a developed concept of Risk Priority Number (RPN) calculation, with determination of main RPN components rating scales, in order to carry out the FMEA (Failure Mode and Effects Analysis) risk analysis of FRA implementation was done. The results allow lining up of the identified potential incompatibilities according to their criticality to the system. In effect it can be said that each modification in a management system, related to safety, influence the safety itself. Nevertheless, this influence does not always lead to negative impact.
SELAMAT: A New Secure and Lightweight Multi-Factor Authentication Scheme for Cross-Platform Industrial IoT Systems
Authors: Khalid Haqi , Hashim Shaiful Jahari , Ahmad Sharifah Mumtazah Syed , Hashim Fazirulhisyam , Chaudhary Muhammad Akmal
Published: February 2021

The development of the industrial Internet of Things (IIoT) promotes the integration of the cross-platform systems in fog computing, which enable users to obtain access to multiple application located in different geographical locations. Fog users at the network’s edge communicate with many fog servers in different fogs and newly joined servers that they had never contacted before. This communication complexity brings enormous security challenges and potential vulnerability to malicious threats. The attacker may replace the edge device with a fake one and authenticate it as a legitimate device. Therefore, to prevent unauthorized users from accessing fog servers, we propose a new secure and lightweight multi-factor authentication scheme for cross-platform IoT systems (SELAMAT). The proposed scheme extends the Kerberos workflow and utilizes the AES-ECC algorithm for efficient encryption keys management and secure communication between the edge nodes and fog node servers to establish secure mutual authentication. The scheme was tested for its security analysis using the formal security verification under the widely accepted AVISPA tool. We proved our scheme using Burrows Abdi Needham’s logic (BAN logic) to prove secure mutual authentication. The results show that the SELAMAT scheme provides better security, functionality, communication, and computation cost than the existing schemes.
A Study Validating the Estimation of Anterior Chamber Depth and Iridocorneal Angle with Portable and Non-Portable Slit-Lamp Microscopy
Authors: Shimizu Eisuke , Yazu Hiroyuki , Aketa Naohiko , Yokoiwa Ryota , Sato Shinri , Yajima Junichiro , Katayama Taiichiro , Sato Rio , Tanji Makoto , Sato Yasunori , Ogawa Yoko , Tsubota Kazuo
Published: February 2021

This study assessed the anterior chamber depth (ACD) and iridocorneal angle using a portable smart eye camera (SEC) compared to the conventional slit-lamp microscope and anterior-segment optical coherence tomography (AS-OCT). This retrospective case-control study included 170 eyes from 85 Japanese patients. The correlation between the ACD evaluations conducted with the SEC and conventional slit-lamp was high (r = 0.814). The correlation between the Van-Herick Plus grade obtained using two devices was also high (r = 0.919). A high kappa value was observed for the Van-Herick Plus grading (Kappa = 0.757). A moderate correlation was observed between the ACD measured using AS-OCT and the slit-lamp image acquired with the conventional slit-lamp microscope and SEC (r = 0.609 and 0.641). A strong correlation was observed between the trabecular-iris angle (TIA) measured using AS-OCT and Van-Herick Plus grade obtained with the conventional slit-lamp microscope and SEC (r = 0.702 and 0.764). Strong correlations of ACD evaluation and high kappa value of the Van-Herick Plus grading indicated the adequate subjective assessment function of the SEC. Moderate correlations between the ACD objective measurement and evaluation and strong correlation between the TIA and Van-Herick Plus grade suggested the good objective assessment function of the SEC. The SEC demonstrated adequate performance for ACD evaluation and angle estimation.
A Review on Functionalized Graphene Sensors for Detection of Ammonia
Authors: Tang Xiaohui , Debliquy Marc , Lahem Driss , Yan Yiyi , Raskin Jean-Pierre
Published: February 2021

Since the first graphene gas sensor has been reported, functionalized graphene gas sensors have already attracted a lot of research interest due to their potential for high sensitivity, great selectivity, and fast detection of various gases. In this paper, we summarize the recent development and progression of functionalized graphene sensors for ammonia (NH3) detection at room temperature. We review graphene gas sensors functionalized by different materials, including metallic nanoparticles, metal oxides, organic molecules, and conducting polymers. The various sensing mechanism of functionalized graphene gas sensors are explained and compared. Meanwhile, some existing challenges that may hinder the sensor mass production are discussed and several related solutions are proposed. Possible opportunities and perspective applications of the graphene NH3 sensors are also presented.
A Comparative Analysis of the Response of GNSS Receivers under Vertical and Horizontal L1/E1 Chirp Jamming
Authors: Pavlovčič-Prešeren Polona , Dimc Franc , Bažec Matej
Published: February 2021

Jamming is becoming a serious threat to various users of global navigation satellite systems (GNSS). Therefore, live monitoring tests are required to estimate the sensitivity range of GNSS receivers under jamming. This study analyses the response of some mass-market and professional-grade receivers to intentional interferences based on different 3D jammer positions. First, the vertical jamming was investigated, followed by a horizontal experiment where the receivers were placed at three locations while the jammer was moving within a triangular area. The aim was to determine a fingerprint of the influence of the L1/E1 chirp jammer on receivers used in the research. The results show that low-cost receivers are much more susceptible to interference, while the latest generation of GNSS geodetic receivers are much more resilient. It is encouraging that positioning in the presence of jamming could be achieved on a larger scale, especially by using professional receivers. An attempt to position the jammer will be left for trials when a more frequency stable device is applied.
Hardware-in-the-Loop Simulations with Umbra Conditions for Spacecraft Rendezvous with PMD Visual Sensors
Authors: Klionovska Ksenia , Burri Matthias
Published: February 2021

This paper addresses the validation of a robust vision-based pose estimation technique using a Photonic Mixer Device (PMD) sensor as a single visual sensor in the close-range phase of spacecraft rendezvous. First, it was necessary to integrate the developed hybrid navigation technique for the PMD sensor into the hardware-in-the-loop (HIL) rendezvous system developed by the German Aerospace Center (DLR). Thereafter, HIL tests were conducted using the European Proximity Operation Simulator (EPOS) with sun simulation and in total darkness. For the future missions with an active sensor, e.g., a PMD camera, it could be useful to use only its own illumination during the rendezvous phase in penumbra or umbra, instead of additional flash light. In some tests, the rotational rate of the target object was also tuned. Unlike the rendezvous tests in other works, here we present for the first time closed-loop approaches with only depth and amplitude images of a PMD sensor. For the rendezvous tests in the EPOS laboratory, the Argos3D camera was used at the range of 8 to 5.5 m; the performance showed promising results.
Solid-Phase Extraction of Aristolochic Acid I from Natural Plant Using Dual Ionic Liquid-Immobilized ZIF-67 as Sorbent
Authors: Chen Pei , Li Xiaoman , Yan Xuemin , Tian Minglei
Published: February 2021

(1) Background: ZIF-67 is one of the most intriguing metal–organic frameworks already applied in liquid adsorption. To increase its adsorption performance, dual ionic liquids were immobilized on ZIF-67 in this research; (2) Methods: The obtained sorbent was used to adsorb aristolochic acid I (AAI) in standard solutions. Then, the sorbent was applied in solid-phase extraction to remove AAI from Fibraurea Recisa Pierre extracted solution. (3) Results: By analyzing the adsorption models, the highest adsorption capacity of immobilized sorbent (50.9 mg/g) was obtained at 25 °C within 120 min. In the SPE process, 0.02 mg of AAI was removed per gram of herbal plant, the adequate recoveries were in the range of 96.2–100.0%, and RSDs were 3.5–4.0%; (4) Conclusions: The provided experimental data revealed that ZIF-67@EIM-MIM was an excellent potential sorbent to adsorb and remove AAI from herbal plant extract, and the successful separation indicated that this sorbent could be an ideal material for the pretreatment of herbal plants containing AAI.
Effect of Climate Variability on Green and Blue Water Resources in a Temperate Monsoon Watershed, Northeastern China
Authors: Jiang Junchao , Lyu Leting , Han Yuechi , Sun Caizhi
Published: February 2021

Over 80% of global grain production relies on green water, water from precipitation that is stored in unsaturated soil and supports plant growth. Blue water, precipitation that turns into surface water and groundwater, is also a vital surface water resource, and it can be directly utilized. The Tanghe River Basin is a typical temperate continental monsoon watershed in Northern China where residents and crops rely on blue and green water resources. In this study, the spatiotemporal distributions of water resources in the Tanghe River Basin were simulated using the soil and water assessment tool (SWAT) model for the period between 1970 and 2015. The results demonstrate that the Nash–Sutcliffe efficiency and coefficient of determination were both higher than 0.64 during the calibration and validation periods at all hydrological stations, indicating high simulation accuracy. The average annual water resources of the Tanghe River Basin are 759.37 mm. Green and blue water account for 68% and 32% of the total water resources, respectively. The study period was divided into the reference period (1970–1976) and the variation period (1977–2015), to explore the impact of climate change on the green and blue water resources of the Tanghe River Basin water resources. Compared with the reference period, the average green and blue water resources in the variation period decreased by 78.48 and 35.94 mm/year, and their rate changes were −13.45% and −13.17%, respectively. The water resource relative change rates were high in the south and low in the north, and they were predominantly affected by precipitation. This study improves our understanding of the hydrological processes as well as the availability of blue and green water in the study region, and can prove beneficial in promoting the sustainable development of small basins and the integrated watershed management in areas with similar climatic conditions.
Botulinum Toxin Type A to Improve Facial Symmetry in Facial Palsy: A Practical Guideline and Clinical Experience
Authors: de Sanctis Pecora Carla , Shitara Danielle
Published: February 2021

Unilateral peripheral facial nerve palsy jeopardizes quality of life, rendering psychological consequences such as low self-esteem, social isolation, anxiety, and depression. Among therapeutical approaches, use of Botulinum toxin type A (BoNT-A) on the nonparalyzed side has shown promising results and improvement of quality of life. Nevertheless, the correct technique is paramount, since over-injection of the muscles can result in lack of function, leading to a “paralyzed” appearance, and even worse, functional incompetence, which may cause greater distress to patients. Therefore, the objective of this article is to provide a practical guideline for botulinum toxin use in facial palsy. To this aim, adequate patient assessment, BoNT-A choice, injection plan and dosage, and injection techniques are covered.
Identification, Distribution, and Habitat Suitability Models of Ixodid Tick Species in Cattle in Eastern Bhutan
Authors: Namgyal Jamyang , Lysyk Tim J. , Couloigner Isabelle , Checkley Sylvia , Gurung Ratna B. , Tenzin Tenzin , Dorjee Sithar , Cork Susan C.
Published: February 2021

Tick infestation is the most reported parasitological problem in cattle in Bhutan. In May and June 2019, we collected ticks from 240 cattle in two districts of Eastern Bhutan. Tick presence, diversity, and infestation prevalence were examined by morphological identification of 3600 live adult ticks. The relationships between cattle, geographic factors, and infestation prevalence were assessed using logistic regression analyses. Habitat suitability for the tick species identified was determined using MaxEnt. Four genera and six species of ticks were found. These were Rhipicephalus microplus (Canestrini) (70.2% (95% confidence interval (CI): 68.7–71.7)), Rhipicephalus haemaphysaloides Supino (18.8% (95% CI: 17.5–20.1)), Haemaphysalis bispinosa Neumann (8.2% (95% CI: 7.3–9.1)), Haemaphysalis spinigera Neumann (2.5% (95% CI: 2–3)), Amblyomma testudinarium Koch (0.19% (95% CI: 0.07–0.4)), and a single unidentified Ixodes sp. Logistic regression indicated that the variables associated with infestation were: longitude and cattle age for R. microplus; latitude for R. haemaphysaloides; and altitude and cattle breed for H. bispinosa and H. spinigera. MaxEnt models showed land cover to be an important predictor for the occurrence of all tick species examined. These findings provide information that can be used to initiate and plan enhanced tick surveillance and subsequent prevention and control programs for ticks and tick-borne diseases in cattle in Bhutan.
Water Quality-Based Double-Gates Control Strategy for Combined Sewer Overflows Pollution Control
Authors: Wei Zhongqing , Shangguan Haidong , Zhan Jiajun , Lin Ruisheng , Huang Xiangfeng , Lu Lijun , Li Huifeng , Du Banghao , Fan Gongduan
Published: February 2021

The combined sewer overflows (CSO) pollution has caused many serious environmental problems, which has aroused a worldwide concern. Traditional interception-storage measures, which exhibit the disadvantages of the larger storage tank volume and the low concentration, cannot efficiently control the CSO pollution. To solve this problem, a water quality-based double-gate control strategy based on the pollution based real-time control (PBRTC) rule was proposed, and the chemical oxygen demand (COD) concentration was taken as the control index. A case study was carried out in Fuzhou, China as an example, in which the hydraulic and water quality model were constructed to evaluate two schemes. According to the results, compared to the traditional scheme, the double-gate scheme can not only reduce the storage tank volume by 1515 m3, but also increase the average COD interception rate by 1.84 times, thus ensuring the effective and stable operation of the facility. Furthermore, the traditional scheme and the double-gate scheme were evaluated under design rainfall beyond the design return period, which confirmed the high performance of the double-gate scheme in controlling CSO pollution.
Women—An Open Access Journal
Authors: Seeman Mary V.
Published: February 2021

It is time for a new comprehensive journal about women [...]
Prevalence and predictors of potentially inappropriate prescribing in middle-aged adults: a repeated cross-sectional study
Authors: Khatter Amandeep , Moriarty Frank , Ashworth Mark , Durbaba Stevo , Redmond Patrick
Published: February 2021

Background

Potentially inappropriate prescribing (PIP) is common in older adults and known to be associated with polypharmacy and multimorbidity. Less is known about the prevalence and causes of PIP in middle-aged adults.

Aim

To determine the prevalence and predictors of PIP in middle-aged adults.

Design and setting

A repeated cross-sectional study was conducted using primary care data in London.

Method

PIP was defined using the PRescribing Optimally in Middle-aged People’s Treatments (PROMPT) criteria. Prescribing and demographic data were extracted from Lambeth DataNet (LDN), a pseudonymised database of all patients registered at general practices in Lambeth, for those aged 45–64 years prescribed ≥1 medicines in each year from 2014–2019 (n = 46 633–52 582). Prevalence and trends over 6 years were investigated, including the association of PIP with polypharmacy, multimorbidity, deprivation, sex, and age.

Results

The prevalence of PIP decreased from 20% in 2014 to 18% in 2019. The most prevalent PROMPT criteria in 2019 were the use of ≥2 drugs from the same pharmacological class (7.6%), use of non-steroidal anti-inflammatory drugs for >3 months (7.1%) and use of proton pump inhibitors above recommended maintenance dosages for >8 weeks (3.1%). Over the study period, the prevalence of multimorbidity increased (47–52%) and polypharmacy remained stable (27%). Polypharmacy, multimorbidity, deprivation, and age were independently associated with PIP. Sex was the only variable not associated with PIP.

Conclusion

Almost one-fifth of middle-aged adults prescribed medicines are exposed to PIP, as defined by the PROMPT criteria. This is likely to be linked with exposure to avoidable adverse drug events. The PROMPT criteria may provide a useful aid in interventions to optimise prescribing.
Measures of Regional Labour Productivity
Authors: Burtseva T. A.
Published: February 2021

In this article, in the form of publication, are presented key study ﬁndings that cover both methodological issues of measurement and comprehensive analysis of regional labor productivity, along with extended formulations of study results. Based on the experience of domestic and foreign statisticians, the author substantiates the system of regional labour productivity indicators required for its integrated assessment. In the author’s opinion, this system is needed in a formation of a single coordinated approach to the calculation of labour productivity from the perspective of branches, enterprises, and constituent entities of the Russian Federation.

The introduction argues for the relevance of the issues related to measuring regional labour productivity, which is necessary to evaluate the progress of the Federal Project “Systemic Measures to Improve Labor Productivity” implemented under the national project “Labor Productivity and Employment Support”.

The author justiﬁes the solution to the problem of clustering regions by regional labour productivity indicator using a combined approach, which explains the trends in the economic development of the regions of Russia in the selected clusters.

The ﬁnal part of the article concludes that the study is relevant in assessing the factors of regional labour productivity needed to identify growth reserves or to prevent stagnation in economic development, measured, in particular, by means of a basic indicator of the economic production efficiency in constituent entities of the Russian Federation.
Electrolyte Changes in Contemporary Hemodialysis: A Secondary Analysis of the Monitoring in Dialysis Study
Authors: Correa Simon , Scovner Katherine Mikovna , Tumlin James A. , Roy-Chaudhury Prabir , Koplan Bruce A. , Costea Alexandru I. , Kher Vijay , Williamson Don , Pokhariyal Saurabh , McClure Candace K. , Mc Causland Finnian R. , Charytan David M. ,   on behalf of the MiD Investigators and Committees,   MiD Investigators and Committees
Published: February 2021

Key Points

Electrolyte fluxes after contemporary HD and the relationship between serum electrolytes and dialysate prescription remain understudied.

HCO3, Ca, and albumin increased, whereas K, Mg, and PO4 decreased immediately post-HD. Dynamic changes followed at 15- and 30-minutes post-HD.

We provide predictive models to estimate the pre- to post-HD change in serum electrolytes. Validation of models is warranted.

Background

There is a paucity of contemporary data examining electrolyte changes during and immediately after hemodialysis (HD), and their relationship with dialysate prescriptions. This study examines these relationships.

Methods

We analyzed patient (n=66) and HD session–level pre and postdialysis laboratory data (n=1713) over a 6-month period from the Monitoring in Dialysis Study. We fit mixed-effects regression models to analyze electrolyte, BUN, creatinine, and albumin levels immediately post-HD, accounting for pre-HD and dialysate prescriptions. In a subset of US patients (n=40), 15-minute post-HD and 30-minute post-HD values were available at one session. Predictive models were fit to estimate electrolyte levels immediately post-HD, accounting for pre-HD concentrations and dialysate prescriptions.

Results

Serum bicarbonate, calcium, and albumin increased (mean increase 4.9±0.3 mEq/L, 0.7±0.1 mEq/L, and 0.4±0.03 g/dl, respectively), whereas potassium, magnesium, and phosphate decreased immediately post-HD (mean −1.2±0.1 mEq/L, −0.3±0.03 mEq/L, and −3.0±0.2 mg/dl, respectively). Hypokalemia and hypophosphatemia were present in 40% and 67% of immediate post-HD samples, respectively. Dynamic changes were observed in electrolyte concentrations at 15- and 30-minutes post-HD, compared with immediately post-HD.

Conclusions

We describe the magnitude of postdialytic changes in serum electrolytes with contemporary HD, reporting a high incidence of electrolyte abnormalities post-HD, and present predictive nomograms relating electrolyte changes immediately post-HD to dialysate prescriptions. Our results may be useful for clinical care and provide insights for future research on dialysate prescriptions.
Low cost Automation on headlamp control for vehicles
Authors: B Sivashankar , Pradeep K.R. , Asfaq Ahamed N.A
Published: February 2021

Nowadays automobile sector plays an important role in day to day life. Most of the people were using private vehicle instead of public vehicle for their convenient. Amount of usage of vehicle in the year 2016 is increased by 4 times while comparing to the year 2011. At the same time accidents are also increased simultaneously. Even though latest technologies are implemented. As such most of the accidents are happened during night time. Most of the accidents are happened due to reflection or Troxler's Effect of light. So far the vehicles are manufactured with manual head light control. Our project is providing an automatic control of head lamp even for the old model vehicles.
Investigation of mechanical properties on Al 6061-B4C composite by squeeze casting process technique
Authors: Sathishkumar A. , A Gowtham , Jeyasuriya M. , DineshBabu S.
Published: February 2021

Aluminum alloy is widely used in automotive, aerospace and other engineering industries because of its excellent mechanical properties. The main objective is to enhance 6061 Al alloy’s mechanical properties by producing 6061-B4C composite through squeeze casting process. Experimentation was carried out with different micron sizes and weight fraction of B4C particles. The mechanical properties of reinforced metal matrix were experimentally investigated in terms of Ultimate Tensile Strength and Hardness. We observe that these two properties are improved by the reinforcement of B4C particles and applied squeeze pressure.
Analysis of Risk in Construction Projects
Authors: B Dhivya , V Prabu
Published: February 2021

The construction industry is subject to more risk and uncertainty than any other industry. Most of the participants experience risks in cost and time over runs and many times fail to meet quality standards and operational requirements. Therefore the need to increase the understanding of risk management. In this project, the qualitative analysis of all types of risks except financial and economical risks in the construction projects is done by ‘Risk factor and priority model’. The industry has shifted from risk transfer to risk reduction, current risk management systems are inadequate to manage project risks, and lack of joint risk management mechanisms is the key barrier to adequate risk management. SPSS (Statistical Package for Social Sciences) software is used for statistical analysis of the data collected from respondents. The general methodology of this study relies largely on the survey questionnaire which was collected from the local building contractors of different sizes by mail or by personnel meeting. A thorough literature review is initially conducted to identify the risk factors that affect the performance of construction industry as a whole. The survey questionnaire is designed to problem the cross-sectional behavioral pattern of construction risks in construction industry.
Using machine learning algorithms to detect frauds in telephone networks
Authors: Apostu Sergiu
Published: February 2021

This paper presents an analysis of voice traffic in telephone networks, based on machine learning algorithms to detect frauds made by callers. Starting from the raw data set that includes information about the call date, destination number, duration and caller's number, in our approach we were able to identify fraudulent calls in early stages. For balance, the data set was split in 2 parts: one for training and one for testing. To obtain mean’s values from dataset, a standardization technique was applied in order to scale the data before the dimensionality reduction using Principal Component Analysis. Then, the first two components were used as inputs for Logistic Regression and Random Forest models, having the caller as target. Finally, the target was moved on the destination file so as to identify the caller and the moment when the call has started based on a vector representation of words.
Diabetes mellitus e hipertensión arterial como factor de riesgo de mortalidad en pacientes con Covid-19
Authors: Navarrete-Mejía Pedro Javier , Lizaraso-Soto Frank Antonio , Velasco-Guerrero Juan Carlos , Loro-Chero Luis Melchor
Published: February 2021

Objetivo. identificar la posible asociación de diabetes mellitus e hipertensión arterial como factores de riesgo de mortalidad en pacientes con COVID-19. Material y métodos: estudio de cohorte prospectivo, incluye a 1947 pacientes con 30 o más años de edad, atenciones realizadas entre marzo y agosto del 2020; pacientes con diagnóstico clínico y laboratorial de COVID-19; se excluyeron pacientes con inconsistencias en la información registrada, fallecidos en primeras 24 horas o estuvieron muertos al ingreso. Se incluyeron variable periodo de atención, edad, sexo, diabetes mellitus, hipertensión arterial, estancia hospitalaria, frecuencia respiratoria, frecuencia cardiaca, saturación de oxígeno y temperatura; para el análisis se utilizó la prueba chi cuadrado de Pearson, Odds Ratio y prueba T de student para muestras no emparejadas (p <0,05). Resultados: 73% de los fallecidos de sexo masculino (p<0.001), mayor frecuencia entre los 60 – 79 años de edad (54,8%, p<0,001); diabetes como comorbilidad en 17% de los casos (p=0,019) e hipertensión arterial en 24% (p<0,001). Las variables sexo (OR 1,5) y las comorbilidades diabetes (OR 1,4) e hipertensión arterial (OR 1,9) representan factores de riesgo de mortalidad. Conclusiones: la diabetes mellitus e hipertensión arterial, para la población en estudio, se identificaron como factor de riesgo de mortalidad frente al COVID-19.
Características de pacientes con alta clínica post SARS-Cov-2 hospitalizados en EsSalud. Región Lambayeque
Authors: Soto-Cáceres Rosario Alexandra , Terrones-Huamán Cynthia Ivonne , Soto-Cáceres Victor Alberto , Díaz-Vélez Cristian
Published: February 2021

Introducción. La pandemia por Covid 19 ha ocasionado alta letalidad en la región Lambayeque colapsando los hospitales. Objetivos: Describir según genero las características de pacientes con alta clínica post Sars.Cov2 hospitalizados en Essalud de la Región Lambayeque. Material y Métodos: Estudio observacional, retrospectivo, descriptivo, seleccionando una muestra representativa de los casos confirmados COVID 19 entre el 01 de abril al 30 de junio del 2020 en el Hospital Nacional Almanzor Aguinaga Asenjo (HNAAA) y Hospital Luis Heysen Inchaustegui (HLHI); como criterios de exclusión: Aquellos con menos de 48 horas de estancia, los fallecidos y los referidos a otros establecimientos. Se recolectaron los datos de historia clínica en el sistema SGSS, se utilizó el software Excel para el procesamiento de datos. Resultados: se registraron 329 pacientes de los cuales 70% fueron varones, promedio de edad 55,9 +/- 11 años; el diagnóstico fue mediante prueba serológica 80% y Tomografía de tórax 17%. La disnea fue el síntoma predominante 85%, linfopenia 51% y proteína C reactiva alta 39% y LDH alta 35%. El tratamiento fue principalmente oxígeno 89% y enoxaparina 87%, azitromicina 86% y ceftriaxona 70%, las complicaciones hospitalarias fueron el SDRA 88,1% y la neumonía atípica 86,6%, la estancia en hospitalización fue de 7,85 +/- 5,42 días. Conclusiones: La mayoría de hospitalizados en Essalud fueron varones, promedio edad 55,9 años; síntoma principal disnea; predominó la linfopenia con proteína C reactiva y LDH altas; el tratamiento fue en base a oxígeno, y enoxaparina, promedio de estancia en hospitalización de 7,85 días.
¿Es el dímero D un marcador confiable de la letalidad durante la COVID-19 en Hispanoamérica?
Authors: Delgado-Lavado Norma K. , Chigne-Castro Yomayra D. , Espinoza-Cueva Fernando E. , Correa-Verde Christian E. , Vergara-de la Rosa Esteban Y.
Published: February 2021

Carta al editor (sin resumen)
Role of polyphenols in the prevention of immunoinflammatory diseases
Authors: Delmas Dominique
Published: February 2021

Inflammation has been described as an initiator event of major diseases with significant impact in terms of public health such as cardiovascular diseases, autoimmune diseases, eye diseases, age-related diseases and more particularly neurodegenerative diseases, or the occurrence and development of cancers. Among the microcomponents of the diet which can participate in a prevention of inflammation and subsequently to various associated diseases, polyphenols from different origins such as resveratrol, could be good candidates. Indeed, in this presentation, we highlight the potential effect of polyphenol on both interleukins secretion by pro-inflammatory lymphocytes Th17 and on the lymphocyte differentiation. In this process, we demonstrate the main role of the NAD-dependent deacetylase, Sirtuin 1 and of the nuclear factor STAT3. T lymphocytes that are not only the cells where the STAT3 factor plays an important role, it is also the case of macrophages where this nuclear factor makes it possible to activate the transcription of genes encoding pro-inflammatory interleukins such as interleukin-6 and -8. Furthermore, macrophages are also able to produce interleukin-1β from an inflammatory complex namely inflammasome. In this way, polyphenols could reduce interleukin-6 level thus down regulates STAT3 activation in macrophages, leading to the impairment of the running inflammatory amplification loop between macrophages and chondrocytes and subsequently could reduce some inflammatory diseases such as arthritis.
Diseños biomiméticos
Authors:   , Venturelli Leonardo
Published: February 2021

La adhesión del suelo sobre la superficie de los órganos de laboreo representa uno de los principales factores críticos junto a la resistencia al deslizamiento y al desgaste por abrasión. Afecta el rendimiento de numerosas máquinas agrícolas, civiles y de movimiento de suelos, aumentando el consumo de energía con consecuencias negativas sobre los costos de producción y el ambiente. En la historia del diseño de maquinaria agrícola fueron empleadas distintas estrategias para minimizar su impacto, la modificación de la superficie, la reducción del área de contacto, la utilización de distintos materiales y métodos físicos, la lubricación, la electro-ósmosis y el empleo de vibraciones. En los últimos años comenzaron a desarrollarse tecnologías para disminuir la adhesión del suelo sobre los órganos de remoción empleando el enfoque biomimético. La biomimética es definida como una disciplina que engloba el estudio de las propiedades funcionales de los sistemas biológicos para el desarrollo de nuevas tecnologías. A partir de la observación de las características anti-adhesivas de los insectos de suelo, específicamente la cutícula de la cabeza y del tórax del bicho torito hembra (Diloboderus abderus) se diseñó una superficie para ser aplicada en órganos que actúen en remoción del suelo. Este trabajo pretende determinar la relación entre dos variables: la fuerza de adhesión normal y la humedad gravimétrica del suelo y por otro lado establecer la influencia sobre la demanda de tracción al modificar la topografía de la superficie metálica. Se realizó un ensayo de laboratorio con el fin de cuantificar la adhesión normal y otro ensayo a campo, utilizando un carro dinamométrico, para determinar la demanda de tracción de una púa con diseño biomimético y una púa lisa. La modificación de la superficie metálica redujo la adhesión normal del suelo sobre el metal y fue influenciada por el valor de humedad del suelo. También se manifestó como una diferencia en la demanda de tracción.
FEATURES OF USING PROJECT MANAGEMENT IN THE AGRICULTURAL SECTOR OF THE REGION ON THE BASIS OF AN AGRICULTURAL UNIVERSITY
Authors:   Saratov State Vavilov Agricultural University, Vorotnikov I.L. , Petrov K.A. ,   Saratov State Vavilov Agricultural University, Morenova E.A. ,   Saratov State Vavilov Agricultural University
Published: February 2021

In the current conditions of unstable financial situation in the world, the most important task should be to increase the efficiency of agricultural production, which is the basis of the country's stability. The introduction of project management in the agro-industrial sector can become a growth point not only for individual organizations, but also for the economy of the region as a whole. The purpose of this study is to develop practical recommendations for using project activities in the management of the agricultural sector at the regional level. In studying the project management problem, the following methods were used: general scientific methods for analyzing science works, methods of systemic, comparative analysis, abstract-logical, expert-analytical and sociological methods. The algorithm of university's project activities implementation, on the basis of which its strategic goals are achieved, is considered in detail. A model of modern agricultural project management at the regional level is presented; its problems and solutions are identified. The effect of introducing project-oriented activities in the agricultural sector at the regional level, as well as the need to improve the economic mechanism for developing agriculture in the region, is substantiated. The results of the study are consistent with the hypothesis put forward. In accordance with it, the proposed measures will contribute to the effective implementation of project-oriented management in the regional economy of the agro-industrial complex on the part of factors of managing agricultural sector in the region. The implementation of the proposed development areas will significantly improve existing methods of managing the agro-industrial complex of the region, since the introduction of project management will allow not only to concentrate financial and managerial resources, but also to obtain sustainable indicators of agricultural development.
IDENTIFICATION AND MINIMIZATION OF RISKS FOR THE LOCAL INITIATIVES SUPPORT PROJECTS
Authors:   “Public Administration” Depart., Tsurkan M.V. , Korotkevich E.R. ,   Depart. of Social and Humanitarian Disciplines
Published: February 2021

The purpose of the article is to identify the typical risks of participatory budgeting projects within the framework of the most common regional practice introduced in more than 40 constituent entities of the Russian Federation - a program to support local initiatives and the formation of measures to minimize their occurrence as part of the monitoring function implemented by various stakeholders. Local government bodies, executive authorities of the constituent entity of the Russian Federation, the population of the municipality - the territory of the project are identified as stakeholders for the participatory budgeting projects under consideration. The main element of the research methodology was the structural level method, which allows us to consider the risks of projects supporting local initiatives as an element of the economic system and economic level of public administration in the subject of the Russian Federation. The article clarifies the concept of “project risk management” through the systematization of the economic categories included in it, such as risk, threat, uncertainty, factors of uncertainty and chance, project risk, management system. As a prerequisite for the functioning of the management system, the authors noted the need to take into account risk-forming factors and their sources, as well as elements of uncertainty. The phases and stages of the life cycle of projects supporting local initiatives and typical risks within each of the elements are identified. Measures have been developed to minimize the possibility of the onset of risks of projects supporting local initiatives that can be implemented by various stakeholders as part of the management function “control”. The significance of the identity of representatives of local communities for the implementation of projects supporting local initiatives and minimizing their risks is substantiated. The results of the study can be embedded in the activities of public authorities at the state and municipal levels, of interest to scientists in the field of economics and management.
USE OF SIMULATION MODEL
Authors:   Russian State University of Justice (Kazan branch), Faskhutdinova M.S. , Latfullina D.R. ,   Russian State University of Justice (Kazan branch), Leontyeva O.L. ,   Russian State University of Justice (Kazan branch)
Published: February 2021

The article reveals the concept of simulation modeling, which remains the generally recognized method of research in various fields of science, production, and business. The more complex are the challenges facing modeling, the greater is the need for computing resources. In the modern world, computers and special software are used to calculate and process large amounts of data. The method of simulation modeling is used for the most frequent study of economic problems, their behavior, impact on the situation and development of factors. This modeling technique is often used to analyze complex multi-level business systems. It is based on statistical tests that help calculate random factors. The simulation method allows you to solve problems when you need to quickly perform calculations. The advantages of the modeling method are: the use of special software that increases data processing speed and minimizes the number of errors; repeated or indirect experiments without negative impact on the system; modeling the system for a long period of time or analysis of its activity over a certain period of time; application of software that allows you to bring the model as close as possible to real data; ability to change variables; the use of the model as a training material for the experiment. A feature of simulation can be called mathematical tools that are as close as possible to reality in order to identify the processes existing in the system and to bring the indicators to real values.
EFFECTIVE MOTIVATION SYSTEM AS A TOOL TO INCREASE THE COMPANY COMPETITIVENESS
Authors:   Kazan (Volga region) Federal University, Sharafutdinova N.S. , Kuz’mina M.S. ,   Kazan (Volga region) Federal University
Published: February 2021

The article discusses current issues of increasing competitiveness through the introduction of an effective motivation system. In literary sources, the authors proposed various approaches to the formation of a motivation system for employees. The general opinion of the authors is that the motivation system must be changed as a whole, the employee must have complete information on how to achieve maximum performance, the elements of motivation are differentiated and their choice depends on the competencies of the employees. The motivation system is aimed at ensuring that the employee is focused on the effective implementation of his work. The determination of the constituent elements of a motivation system depends on a number of factors. The article considers an example of a system of motivation for an educational services company. The authors believe that when developing a motivation system, it is necessary to digitize the goal for the company and employee. When developing a motivation system, it is necessary to take into account that the employee is interested in increasing the company’s performance. The constituent elements of a motivation system may vary. These include a fixed part, a premium part, fines, performance indicators. According to the authors, it is necessary to introduce innovations into the motivation system taking into account changes in employee behavior, their effectiveness, and market conditions. Innovations should be systematic. When developing a motivation system, it is advisable to focus on understanding the valuable final product. A valuable end product is differentiated for employees and takes into account their competencies, functionality, and performance. If the employees believe in the high value of the final product, they will understand that they are an integral part of a large chain, and that the company’s performance and competitiveness depend on the result of their work.
Green areas in Białystok
Authors: Niedzielko Jolanta , Łochnicka Agata
Published: February 2021

This work contains a description of four housing estates in Białystok from different decades of the 20th century. The approximate percentage of green areas in these states was determined based on available sources. Existing development plans were analysed with a view to the records regarding greenery. Own observations allowed to define the state of green areas – their functions, accessibility, quality and relation to space. The results of the analysis made it possible to discuss the observed problems and indicated the ways to solve them.
‘Economic, Education, Environment’ Pelatihan Guru TK Dan TPA Serta Bakti Sosial Di Mesjid At-Taqwa Universitas Pancasila
Authors: Widyastuti Sri , Parenrengi Sudarmin , Ichwani Tia
Published: February 2021

Early childhood education is the basis for the development of individual character in his future life. Teachers are not only required to master the fields of science, teaching materials, and methods, but also must be able to motivate students to have skills, be creative and have broad insights. This relates to the potential that exists in the community that has not been carried out optimally, so it requires the involvement of other parties in this case universities to provide counseling and training to the community. Therefore, there was a training and counseling activity for kindergarten and TPA teachers located at the At-Taqwa Mosque.
Kegiatan Pelatihan Peningkatan Adversity Quotient (AQ) Bagi Usaha Kecil Dan Menengah (UKM) Kreatif Di Kota Bogor
Authors: Whisnu H Tyahya , Retno Bayu , Widayadi Wasi
Published: February 2021

Small and Medium Enterprises (SMEs) have been proven to make significant positive contributions to efforts to tackle economic and social problems in Bogor City. But in fact people with an entrepreneurial mindset alone are not enough to succeed because many are still unable to overcome the problem of adversity. Without a high advertisy quotient (AQ), it is feared that someone will experience frustration and setbacks in becoming an entrepreneur. For this reason, to solve the existing problems, the Adversity Quotient (AQ) Enhancement Training for Creative Small & Medium Enterprises (SMEs) is given. Adversity Quotient is intelligence to overcome difficulties.
Pelatihan Pelayanan Prima untuk Mendukung Pembelajaran Jarak Jauh Bagi Guru Al-Azhar DKI Jakarta
Authors: Ichwani Tia , Munira Mira , Hilmiyah Nurul , Putriana Lies
Published: February 2021

Perusahaan atau organisasi yang bergerak di bidang jasa, selalu mengutamakan pelayanan sebagai produk utama mereka. Pelayanan prima sangat diutamakan demi tercapainya kepuasan pelanggan, terutama di lembaga pendidikan. Lembaga pendidikan tidak hanya mengajarkan ilmu pengetahuan atau ilmu science, tetapi juga mengajarkan tentang bagaimana cara individu memanusiakan manusia dan juga mencitai alam beserta isinya. Melalui pendidikan berkualitas, relevansi pendidikan dalam mencapai titik perubahan manusia dapat terwujud. Sekolah Al-Azhar didirikan oleh Yayasan Pesantren Islam Al-Azhar pada tahun 1963 dan merupakan salah satu pelopor sekolah islam modern di Jakarta. Sekolah ini dilengkapi dengan fasilitas pendidikan yang lengkap dengan tenaga pengajar yang berkualitas. Fakultas Ekonomi dan Bisnis Universitas Pancasila bekerjasama dengan YPAI Al-Azhar DKI Jakarta dalam memberikan webinar pelatihan pelayanan prima bagi guru dan karyawan. Pelatihan yang diberikan merupakan pelatihan pelayanan prima guna meningkatkan pemahaman dan keterampilan guru Al Azhar di Wilayah DKI Jakarta dalam memberikan pelayanan atau pengajaran kepada siswa