bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables 1-6 from LRP1B Deletion in High-Grade Serous Ovarian Cancers Is Associated with Acquired Chemotherapy Resistance to Liposomal Doxorubicin
Authors: Cowin Prue A. , George Joshy , Fereday Sian , Loehrer Elizabeth , Van Loo Peter , Cullinane Carleen , Etemadmoghadam Dariush , Ftouni Sarah , Galletta Laura , Anglesio Michael S. , Hendley Joy , Bowes Leanne , Sheppard Karen E. , Christie Elizabeth L. , Pearson Richard B. , Harnett Paul R. , Heinzelmann-Schwarz Viola , Friedlander Michael , McNally Orla , Quinn Michael , Campbell Peter , deFazio Anna , Bowtell David D.L.
Published: March 2023

PDF file - 119K, Supp Table S1. Regions of differential copy number change between primary tumor samples and most distant abdominal deposit Supp Table S2. Top 50 pathways altered between primary tumors and abdominal deposits Supp Table S3. Individual patient chemotherapy regimens for paired primary and relapse ovarian tumors Supp Table S4. BRCA mutation details for mutation positive cases Supp Table S5. Regions of discrete copy number amplification Supp Table S6. Regions of discrete copy number deletion
Supplementary Figures 1-10 from LRP1B Deletion in High-Grade Serous Ovarian Cancers Is Associated with Acquired Chemotherapy Resistance to Liposomal Doxorubicin
Authors: Cowin Prue A. , George Joshy , Fereday Sian , Loehrer Elizabeth , Van Loo Peter , Cullinane Carleen , Etemadmoghadam Dariush , Ftouni Sarah , Galletta Laura , Anglesio Michael S. , Hendley Joy , Bowes Leanne , Sheppard Karen E. , Christie Elizabeth L. , Pearson Richard B. , Harnett Paul R. , Heinzelmann-Schwarz Viola , Friedlander Michael , McNally Orla , Quinn Michael , Campbell Peter , deFazio Anna , Bowtell David D.L.
Published: March 2023

PDF file - 1.8MB, Supp Fig S1. Variation in DNA copy number and gene expression among primary ovarian tumors and associated abdominal deposits Supp Fig S2. Heatmap of CNC in paired primary - relapse tumors for oncogenes/tumour suppressors and literature derived candidates Supp Fig S3. Box plots of gene expression changes of 19 literature derived candidates associated with resistance in ovarian cancer Supp Fig S4. Copy number genome in line view of primary sensitive tumor - relapse resistant ascites pairs Supp Fig S5. Genome in line view of primary resistant tumor - relapse resistant ascites pairs Supp Fig S6. Genome in line view of primary tumor - primary ascites samples Supp Fig S7. Schematic of reported mutations in LRP1B Supp Fig S8. LRP1B expression in 32 ovarian cancer and normal cell lines Supp Fig S9. LRP1B siRNA and minigene sequence targets Supp Fig S10. siRNA knockdown of LRP1B in vitro using individual siRNA constructs alters drug sensitivity in ovarian cancer cell lines, Kuramochi and JHOS3
Supplementary Table 5 from Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
Authors: Tang Xiaohu , Lucas Joseph E. , Chen Julia Ling-Yu , LaMonte Gregory , Wu Jianli , Wang Michael Changsheng , Koumenis Constantinos , Chi Jen-Tsan
Published: March 2023

XLS file - 33K
Supplementary Table 4 from Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
Authors: Tang Xiaohu , Lucas Joseph E. , Chen Julia Ling-Yu , LaMonte Gregory , Wu Jianli , Wang Michael Changsheng , Koumenis Constantinos , Chi Jen-Tsan
Published: March 2023

PDF file - 12K
Supplementary Figure 1 from Reprogramming Tumor-Associated Dendritic Cells In Vivo Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer
Authors: Cubillos-Ruiz Juan R. , Baird Jason R. , Tesone Amelia J. , Rutkowski Melanie R. , Scarlett Uciane K. , Camposeco-Jacobs Ana L. , Anadon-Arnillas Jorge , Harwood Noah M. , Korc Murray , Fiering Steven N. , Sempere Lorenzo F. , Conejo-Garcia Jose R.
Published: March 2023

PDF file - 178K, Enhanced local and splenic anti-tumor responses in mice treated with anti-CD40 and Dmi155-PEI.
Supplementary Table 2 from Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
Authors: Tang Xiaohu , Lucas Joseph E. , Chen Julia Ling-Yu , LaMonte Gregory , Wu Jianli , Wang Michael Changsheng , Koumenis Constantinos , Chi Jen-Tsan
Published: March 2023

PDF file - 201K
Supplementary Table 1 from Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
Authors: Tang Xiaohu , Lucas Joseph E. , Chen Julia Ling-Yu , LaMonte Gregory , Wu Jianli , Wang Michael Changsheng , Koumenis Constantinos , Chi Jen-Tsan
Published: March 2023

XLS file - 84K
Supplementary Figure 2 from Cell Death via DR5, but not DR4, Is Regulated by p53 in Myeloma Cells
Authors: Surget Sylvanie , Chiron David , Gomez-Bougie Patricia , Descamps Géraldine , Ménoret Emmanuelle , Bataille Régis , Moreau Philippe , Le Gouill Steven , Amiot Martine , Pellat-Deceunynck Catherine
Published: March 2023

PDF file - 74K, Nutlin-3a and melphalan induced p53 expression and caspase 3 cleavage
Supplementary Figure 1 from Cell Death via DR5, but not DR4, Is Regulated by p53 in Myeloma Cells
Authors: Surget Sylvanie , Chiron David , Gomez-Bougie Patricia , Descamps Géraldine , Ménoret Emmanuelle , Bataille Régis , Moreau Philippe , Le Gouill Steven , Amiot Martine , Pellat-Deceunynck Catherine
Published: March 2023

PDF file - 94K, TP53Wt HMCLs overexpressed p21, Bax and MDM2 compared with TP53Abn HMCLs
Supplementary Methods and Materials from Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer
Authors: Szabova Ludmila , Yin Chaoying , Bupp Sujata , Guerin Theresa M. , Schlomer Jerome J. , Householder Deborah B. , Baran Maureen L. , Yi Ming , Song Yurong , Sun Wenping , McDunn Jonathan E. , Martin Philip L. , Van Dyke Terry , Difilippantonio Simone
Published: March 2023

PDF file - 192K
Supplementary Table 1 from Mesenchymal Stromal Cell Mutations and Wound Healing Contribute to the Etiology of Desmoid Tumors
Authors: Carothers Adelaide M. , Rizvi Hira , Hasson Rian M. , Heit Yvonne I. , Davids Jennifer S. , Bertagnolli Monica M. , Cho Nancy L.
Published: March 2023

PDf file - 56K
Supplementary Figure 5 from Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer
Authors: Szabova Ludmila , Yin Chaoying , Bupp Sujata , Guerin Theresa M. , Schlomer Jerome J. , Householder Deborah B. , Baran Maureen L. , Yi Ming , Song Yurong , Sun Wenping , McDunn Jonathan E. , Martin Philip L. , Van Dyke Terry , Difilippantonio Simone
Published: March 2023

PDF file - 253K, Gene expression analysis
Supplementary Figure 4 from Mesenchymal Stromal Cell Mutations and Wound Healing Contribute to the Etiology of Desmoid Tumors
Authors: Carothers Adelaide M. , Rizvi Hira , Hasson Rian M. , Heit Yvonne I. , Davids Jennifer S. , Bertagnolli Monica M. , Cho Nancy L.
Published: March 2023

PDf file - 2.4MB, DT-derived MSCs expressed TGFβ1, 2, 3, active β integrin, and displayed a prominent filamentous actin cytoskeleton. Fluorescent immunohistochemistry of DT-derived MSCs showed predominantly cell surface and cytoplasmic staining for TGFβ1, 2, 3 (top, red), and the active form of β1 integrin (bottom, red) (A). Alexa Fluor 568-labeled phalloidin, which binds to F-actin, showed that DT-derived MSCs are characterized by a prominent cytoskeleton (B). Original magnification for TGFβ1, 2, 3 was 40X. Images for active β1 integrin and phalloidin were taken at 60X.
Supplementary Figure 4 from Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer
Authors: Szabova Ludmila , Yin Chaoying , Bupp Sujata , Guerin Theresa M. , Schlomer Jerome J. , Householder Deborah B. , Baran Maureen L. , Yi Ming , Song Yurong , Sun Wenping , McDunn Jonathan E. , Martin Philip L. , Van Dyke Terry , Difilippantonio Simone
Published: March 2023

PDF file - 325K, Nuclear p53 expression correlates positively with loss of wild type allele in serous epithelial ovarian carcinomas in p53m/+ mutant mice
Supplementary Figure 3 from Mesenchymal Stromal Cell Mutations and Wound Healing Contribute to the Etiology of Desmoid Tumors
Authors: Carothers Adelaide M. , Rizvi Hira , Hasson Rian M. , Heit Yvonne I. , Davids Jennifer S. , Bertagnolli Monica M. , Cho Nancy L.
Published: March 2023

PDF file - 4.1MB, Cell morphology of desmoid-derived MSC line was polyploid. Morphological features of first passage cells cultured from a DT are shown at low (A), intermediate (B), and high (C) densities. Cells aligned at high density (white arrow) to form sites of extensive cell-cell contact denoting polarity. Clusters of cells at high density spontaneously differentiated into neuronal-like cells (D). Original magnification was 10X.
Supplementary Figure 6 from NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells
Authors: Yap Kai Lee , Fraley Stephanie I. , Thiaville Michelle M. , Jinawath Natini , Nakayama Kentaro , Wang Jianlong , Wang Tian-Li , Wirtz Denis , Shih Ie-Ming
Published: March 2023

PDF file - 52K, Silencing profilin-1 in HeLa cell line
Supplementary Figure 5 from Increased Survival of Glioblastoma Patients Who Respond to Antiangiogenic Therapy with Elevated Blood Perfusion
Authors: Sorensen A. Gregory , Emblem Kyrre E. , Polaskova Pavlina , Jennings Dominique , Kim Heisoog , Ancukiewicz Marek , Wang Meiyun , Wen Patrick Y. , Ivy Percy , Batchelor Tracy T. , Jain Rakesh K.
Published: March 2023

PDF file - 894K, Figure S5: Arterial Spin Labeling (ASL) Flow and Response to Treatment. (A) Analysis of blood flow as measured by arterial spin labeling (ASL) when applying the patients groups from the macrovessel tumor flow analysis. (B) ASL blood flow when applying the patients groups from the microvessel tumor flow analysis. Figures show log-scaled averaged values (�SEM) and the day -1 values were set as 100% in all lesions. P-values show results of Mann-Whitney tests for the difference between patients with increase in flow and stable or decreased flow (Holm-Bonferroni corrected).
Supplementary Figure 1 from RALBP1/RLIP76 Depletion in Mice Suppresses Tumor Growth by Inhibiting Tumor Neovascularization
Authors: Lee Seunghyung , Wurtzel Jeremy G. T. , Singhal Sharad S. , Awasthi Sanjay , Goldfinger Lawrence E.
Published: March 2023

PDF file - 47K, Knockdown of RLIP76 in B16F10 and LLC tumor cells
Supplementary Figure 2 from Increased Survival of Glioblastoma Patients Who Respond to Antiangiogenic Therapy with Elevated Blood Perfusion
Authors: Sorensen A. Gregory , Emblem Kyrre E. , Polaskova Pavlina , Jennings Dominique , Kim Heisoog , Ancukiewicz Marek , Wang Meiyun , Wen Patrick Y. , Ivy Percy , Batchelor Tracy T. , Jain Rakesh K.
Published: March 2023

PDF file - 1.7MB, Figure S2: Changes in Imaging Parameters over Time. Based on the three patients groups from the microvessel tumor flow analysis, the plots show: (A) contrast-enhanced T1-weighted tumor volumes, (B) FLAIR tumor volumes and (C) permeability (Ktrans) of the tumor over time. Patients with an increase and decrease in flow showed the same changes in contrast-enhanced tumor volume and peritumoral vasogenic edema during treatment. Indeed, redefining PFS using the Response Assessment in Neuro-Oncology (RANO) Working Group criteria instead of Macdonald did not change the outcome of any test in our study. Numerical data show log-scaled averaged values (�SEM) and values at day -1 were set as 100% in all lesions. P-values show results of Mann-Whitney tests for the difference between patients with stable flow and increased or decreased flow (Holm-Bonferroni corrected).
Supplementary Figure 1 from Androgen Deprivation Causes Epithelial–Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy
Authors: Sun Yuting , Wang Bu-Er , Leong Kevin G. , Yue Peng , Li Li , Jhunjhunwala Suchit , Chen Darrell , Seo Kyounghee , Modrusan Zora , Gao Wei-Qiang , Settleman Jeffrey , Johnson Leisa
Published: March 2023

PDf file - 279K
Supplementary Figure 6 from Caveolin-1 Increases Aerobic Glycolysis in Colorectal Cancers by Stimulating HMGA1-Mediated GLUT3 Transcription
Authors: Ha Tae-Kyu , Her Nam-Gu , Lee Min-Goo , Ryu Byung-Kyu , Lee Jin-Hee , Han Jikhyon , Jeong Seong-In , Kang Min-Ju , Kim Nam-Hoon , Kim Hyo-Jong , Chi Sung-Gil
Published: March 2023

PDF file- 341K, Collaborative effect of CAV1 on HMGA1 binding to the GLUT3 chromatin
Supplementary Figure 4 from Loss of Fibroblast HIF-1α Accelerates Tumorigenesis
Authors: Kim Jung-whan , Evans Colin , Weidemann Alexander , Takeda Norihiko , Lee Yun Sok , Stockmann Christian , Branco-Price Cristina , Brandberg Filip , Leone Gustavo , Ostrowski Michael C. , Johnson Randall S.
Published: March 2023

PDF file - 300K, Targeted Deletion of Hif-1� in Stromal Fibroblasts Improves Perivascular Coverage.
Supplementary Figure 4 from Caveolin-1 Increases Aerobic Glycolysis in Colorectal Cancers by Stimulating HMGA1-Mediated GLUT3 Transcription
Authors: Ha Tae-Kyu , Her Nam-Gu , Lee Min-Goo , Ryu Byung-Kyu , Lee Jin-Hee , Han Jikhyon , Jeong Seong-In , Kang Min-Ju , Kim Nam-Hoon , Kim Hyo-Jong , Chi Sung-Gil
Published: March 2023

PDF file- 474K, CAV1 regulation of aerobic glycolysis and mitochondrial function
Supplementary Figure 1 from Loss of Fibroblast HIF-1α Accelerates Tumorigenesis
Authors: Kim Jung-whan , Evans Colin , Weidemann Alexander , Takeda Norihiko , Lee Yun Sok , Stockmann Christian , Branco-Price Cristina , Brandberg Filip , Leone Gustavo , Ostrowski Michael C. , Johnson Randall S.
Published: March 2023

PDF file - 198K, Hif-1a in Macrophages.
Supplementary Table 1 from The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation
Authors: Jun Hyun Jung , Johnson Hannah , Bronson Roderick T. , de Feraudy Sebastien , White Forest , Charest Alain
Published: March 2023

XLS file - 186K, Summary of phosphopeptide MS/MS data
Supplementary Figure Legends 1-6 from CXCR3+ T Regulatory Cells Selectively Accumulate in Human Ovarian Carcinomas to Limit Type I Immunity
Authors: Redjimi Nassima , Raffin Caroline , Raimbaud Isabelle , Pignon Pascale , Matsuzaki Junko , Odunsi Kunle , Valmori Danila , Ayyoub Maha
Published: March 2023

PDF file - 74K
Supplementary Figure 4 from CXCR3+ T Regulatory Cells Selectively Accumulate in Human Ovarian Carcinomas to Limit Type I Immunity
Authors: Redjimi Nassima , Raffin Caroline , Raimbaud Isabelle , Pignon Pascale , Matsuzaki Junko , Odunsi Kunle , Valmori Danila , Ayyoub Maha
Published: March 2023

PDF file - 21K, Assessment of the capacity of CXCR3+ and CXCR3- MTreg to suppress the proliferation of CXCR3+ and CXCR3- effector cells
Supplementary Figure 5 from Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
Authors: Fokas Emmanouil , Im Jae Hong , Hill Sally , Yameen Sabira , Stratford Michael , Beech John , Hackl Wolfgang , Maira Sauveur-Michel , Bernhard Eric J. , McKenna W. Gillies , Muschel Ruth J.
Published: March 2023

PDf file - 90K
Supplementary Figures 1-9 from MET Signaling Regulates Glioblastoma Stem Cells
Authors: Joo Kyeung Min , Jin Juyoun , Kim Eunhee , Ho Kim Kang , Kim Yonghyun , Gu Kang Bong , Kang Youn-Jung , Lathia Justin D. , Ho Cheong Kwang , Song Paul H. , Kim Hyunggee , Seol Ho Jun , Kong Doo-Sik , Lee Jung-Il , Rich Jeremy N. , Lee Jeongwu , Nam Do-Hyun
Published: March 2023

PDF file - 6.4MB, Figure S1: High MET mRNA expression in GBM specimens portends poor patient survival. Figure S2: Dual immunofluorescence of MET and GSC enrichment markers (CD133 and CD15) on the frozen sections of GBM specimens. Figure S3: HGF/MET signaling in GBMs. Figure S4: METhigh cells generated xenograft tumors consisting of both METhigh and METlow/- cells. Figure S5: Immunohistochemical analysis of HGF protein in orthotopic xenograft tumors derived of from GBM 578 (A and C) and 464 (B and D). Figure S6: Effects of MET blockade on cell survival and clonogenicity of GSCs. Figure S7: In vitro migration and invasion assays using GSCs with MET targeting. Figure S8: Immunohistochemical analysis using human nuclei-specific antibody on the sections of GBM xenografts. Figure S9: Limiting dilution sphere forming assay to determine the clonogenic potentials of 822 GSCs after treatments of radiation and SU11274
Supplementary Figure 1 from Acyclic Retinoid Targets Platelet-Derived Growth Factor Signaling in the Prevention of Hepatic Fibrosis and Hepatocellular Carcinoma Development
Authors: Okada Hikari , Honda Masao , Campbell Jean S. , Sakai Yoshio , Yamashita Taro , Takebuchi Yuuki , Hada Kazuhiro , Shirasaki Takayoshi , Takabatake Riuta , Nakamura Mikiko , Sunagozaka Hajime , Tanaka Takuji , Fausto Nelson , Kaneko Shuichi
Published: March 2023

PDF file - 348K, A: Immunohistochemica l staining of collagen 4, desmin, CD31 and Tie2 expression in Pdgf-c T9 or WT mouse livers fed with basal diet or 0.06% peretinoin. B: Densitometric analysis of CD31 - or CD34-positive areas in liver of Pdgf-c T9 Tgmice fed different diets (n=10).
Supplementary Materials and Methods from The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype
Authors: De Bacco Francesca , Casanova Elena , Medico Enzo , Pellegatta Serena , Orzan Francesca , Albano Raffaella , Luraghi Paolo , Reato Gigliola , D'Ambrosio Antonio , Porrati Paola , Patanè Monica , Maderna Emanuela , Pollo Bianca , Comoglio Paolo M. , Finocchiaro Gaetano , Boccaccio Carla
Published: March 2023

PDF file - 125K
Supplementary Table 2 from BCL2 Suppresses PARP1 Function and Nonapoptotic Cell Death
Authors: Dutta Chaitali , Day Tovah , Kopp Nadja , van Bodegom Diederik , Davids Matthew S. , Ryan Jeremy , Bird Liat , Kommajosyula Naveen , Weigert Oliver , Yoda Akinori , Fung Hua , Brown Jennifer R. , Shapiro Geoffrey I. , Letai Anthony , Weinstock David M.
Published: March 2023

PDF file - 18K, Clinical characteristics for the 14 patients outlined in Figure 6A. The majority of cases were previously untreated and harbored 13q deletion, the most common cytogenetic abnormality in CLL. Several higher risk patients with unmutated IGHV, positive ZAP-70, or adverse cytogenetics were also assessed
Supplementary Table 9 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Authors: Hilvo Mika , Denkert Carsten , Lehtinen Laura , Müller Berit , Brockmöller Scarlet , Seppänen-Laakso Tuulikki , Budczies Jan , Bucher Elmar , Yetukuri Laxman , Castillo Sandra , Berg Emilia , Nygren Heli , Sysi-Aho Marko , Griffin Julian L. , Fiehn Oliver , Loibl Sibylle , Richter-Ehrenstein Christiane , Radke Cornelia , Hyötyläinen Tuulia , Kallioniemi Olli , Iljin Kristiina , Orešič Matej
Published: March 2023

Supplementary Table 9 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Supplementary Table 8 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Authors: Hilvo Mika , Denkert Carsten , Lehtinen Laura , Müller Berit , Brockmöller Scarlet , Seppänen-Laakso Tuulikki , Budczies Jan , Bucher Elmar , Yetukuri Laxman , Castillo Sandra , Berg Emilia , Nygren Heli , Sysi-Aho Marko , Griffin Julian L. , Fiehn Oliver , Loibl Sibylle , Richter-Ehrenstein Christiane , Radke Cornelia , Hyötyläinen Tuulia , Kallioniemi Olli , Iljin Kristiina , Orešič Matej
Published: March 2023

Supplementary Table 8 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Supplementary Figure 3 from BCL2 Suppresses PARP1 Function and Nonapoptotic Cell Death
Authors: Dutta Chaitali , Day Tovah , Kopp Nadja , van Bodegom Diederik , Davids Matthew S. , Ryan Jeremy , Bird Liat , Kommajosyula Naveen , Weigert Oliver , Yoda Akinori , Fung Hua , Brown Jennifer R. , Shapiro Geoffrey I. , Letai Anthony , Weinstock David M.
Published: March 2023

PDF file - 12K, Sensitivity of lung cancer cell lines to the PARP1 inhibitor AG014699
Supplementary Figure 1 from BCL2 Suppresses PARP1 Function and Nonapoptotic Cell Death
Authors: Dutta Chaitali , Day Tovah , Kopp Nadja , van Bodegom Diederik , Davids Matthew S. , Ryan Jeremy , Bird Liat , Kommajosyula Naveen , Weigert Oliver , Yoda Akinori , Fung Hua , Brown Jennifer R. , Shapiro Geoffrey I. , Letai Anthony , Weinstock David M.
Published: March 2023

PDF file - 901K, Confocal images were acquired of OCI-LY8 cells either in the (A) absence of irradiation or (B) 30 minutes after 3 Gy IR
Supplementary Table 2 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Authors: Hilvo Mika , Denkert Carsten , Lehtinen Laura , Müller Berit , Brockmöller Scarlet , Seppänen-Laakso Tuulikki , Budczies Jan , Bucher Elmar , Yetukuri Laxman , Castillo Sandra , Berg Emilia , Nygren Heli , Sysi-Aho Marko , Griffin Julian L. , Fiehn Oliver , Loibl Sibylle , Richter-Ehrenstein Christiane , Radke Cornelia , Hyötyläinen Tuulia , Kallioniemi Olli , Iljin Kristiina , Orešič Matej
Published: March 2023

Supplementary Table 2 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Supplementary Table 1 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Authors: Hilvo Mika , Denkert Carsten , Lehtinen Laura , Müller Berit , Brockmöller Scarlet , Seppänen-Laakso Tuulikki , Budczies Jan , Bucher Elmar , Yetukuri Laxman , Castillo Sandra , Berg Emilia , Nygren Heli , Sysi-Aho Marko , Griffin Julian L. , Fiehn Oliver , Loibl Sibylle , Richter-Ehrenstein Christiane , Radke Cornelia , Hyötyläinen Tuulia , Kallioniemi Olli , Iljin Kristiina , Orešič Matej
Published: March 2023

Supplementary Table 1 from Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
Supplementary Figure 1 from FGFR2 Isoforms Support Epithelial–Stromal Interactions in Thyroid Cancer Progression
Authors: Guo Miao , Liu Wei , Serra Stefano , Asa Sylvia L. , Ezzat Shereen
Published: March 2023

PDF file - 622K
Supplementary Methods and Materials, Results from Transcriptional Signatures of Ral GTPase Are Associated with Aggressive Clinicopathologic Characteristics in Human Cancer
Authors: Smith Steven C. , Baras Alexander S. , Owens Charles R. , Dancik Garrett , Theodorescu Dan
Published: March 2023

PDF file - 44K, Transcriptional signatures of Ral GTPase are associated with aggressive clinicopathologic characteristics in human cancer
Supplementary Figure 2 from The Nedd8-Activating Enzyme Inhibitor MLN4924 Induces Autophagy and Apoptosis to Suppress Liver Cancer Cell Growth
Authors: Luo Zhongguang , Yu Guangyang , Lee Hyuk Woo , Li Lihui , Wang Lingyan , Yang Dongqin , Pan Yongfu , Ding Chan , Qian Jing , Wu Lijun , Chu Yiwei , Yi Jing , Wang Xiangdong , Sun Yi , Jeong Lak Shin , Liu Jie , Jia Lijun
Published: March 2023

PDF file - 979K, MLN4924-induced autophagy was partially rescued by N-Acetyl-L-cysteine (NAC)
Supplementary Figure 2 from NF-κB Hyperactivation in Tumor Tissues Allows Tumor-Selective Reprogramming of the Chemokine Microenvironment to Enhance the Recruitment of Cytolytic T Effector Cells
Authors: Muthuswamy Ravikumar , Berk Erik , Junecko Beth Fallert , Zeh Herbert J. , Zureikat Amer H. , Normolle Daniel , Luong The Minh , Reinhart Todd A. , Bartlett David L. , Kalinski Pawel
Published: March 2023

PDF file - 215K, Presence of Treg and Teff markers in tumors correlate with intra-tumoral expression of Teff- and Treg-attracting chemokines
Supplementary Figure 1 from NF-κB Hyperactivation in Tumor Tissues Allows Tumor-Selective Reprogramming of the Chemokine Microenvironment to Enhance the Recruitment of Cytolytic T Effector Cells
Authors: Muthuswamy Ravikumar , Berk Erik , Junecko Beth Fallert , Zeh Herbert J. , Zureikat Amer H. , Normolle Daniel , Luong The Minh , Reinhart Todd A. , Bartlett David L. , Kalinski Pawel
Published: March 2023

PDF file - 191K, Processing of tumors and marginal tissues
Supplementary Figure 3 from Protein Tyrosine Phosphatase Shp2 (Ptpn11) Plays an Important Role in Maintenance of Chromosome Stability
Authors: Liu Xia , Zheng Hong , Qu Cheng-Kui
Published: March 2023

PDF file - 39K, Shp2 depletion causes premature PLK1 and Cyclin B1 degradation
Supplementary Figure 2 from Protein Tyrosine Phosphatase Shp2 (Ptpn11) Plays an Important Role in Maintenance of Chromosome Stability
Authors: Liu Xia , Zheng Hong , Qu Cheng-Kui
Published: March 2023

PDF file - 27K, Shp2-depleted cells fail to sustain nocodazole-induced mitotic arrest
Supplementary Results from miR-23b Represses Proto-oncogene Src Kinase and Functions as Methylation-Silenced Tumor Suppressor with Diagnostic and Prognostic Significance in Prostate Cancer
Authors: Majid Shahana , Dar Altaf A. , Saini Sharanjot , Arora Sumit , Shahryari Varahram , Zaman Mohd Saif , Chang Inik , Yamamura Soichiro , Tanaka Yuichiro , Deng Guoren , Dahiya Rajvir
Published: March 2023

PDF file - 65K, Clinicopathological characteristics of patients and their correlation with miR-23b
Supplementary Figure 4 from miR-23b Represses Proto-oncogene Src Kinase and Functions as Methylation-Silenced Tumor Suppressor with Diagnostic and Prognostic Significance in Prostate Cancer
Authors: Majid Shahana , Dar Altaf A. , Saini Sharanjot , Arora Sumit , Shahryari Varahram , Zaman Mohd Saif , Chang Inik , Yamamura Soichiro , Tanaka Yuichiro , Deng Guoren , Dahiya Rajvir
Published: March 2023

PDF file - 141K, miR-23b directly targets Akt in prostate cancer
Supplementary Figures 1-12, Table 1 from CDK8 Maintains Tumor Dedifferentiation and Embryonic Stem Cell Pluripotency
Authors: Adler Adam S. , McCleland Mark L. , Truong Tom , Lau Shari , Modrusan Zora , Soukup Tim M. , Roose-Girma Merone , Blackwood Elizabeth M. , Firestein Ron
Published: March 2023

PDF file - 1.3MB
Supplementary Figure 2 from Vitronectin–αvβ3 Integrin Engagement Directs Hypoxia-Resistant mTOR Activity and Sustained Protein Synthesis Linked to Invasion by Breast Cancer Cells
Authors: Pola Carolina , Formenti Silvia C. , Schneider Robert J.
Published: March 2023

Supplementary Figure 2 - PDF file 19K, S2. Plating efficiency of MB-435 cells under hypoxia on plastic or vitronectin with beta3 silencing
Supplementary Figure 1 from Vitronectin–αvβ3 Integrin Engagement Directs Hypoxia-Resistant mTOR Activity and Sustained Protein Synthesis Linked to Invasion by Breast Cancer Cells
Authors: Pola Carolina , Formenti Silvia C. , Schneider Robert J.
Published: March 2023

Supplementary Figure 1 - PDF file 20K, S1. Plating efficiency of MB-435 and MB-231 cells on different ECM matrices
Supplementary Tables 3-5 from Deficiency in Mammalian Histone H2B Ubiquitin Ligase Bre1 (Rnf20/Rnf40) Leads to Replication Stress and Chromosomal Instability
Authors: Chernikova Sophia B. , Razorenova Olga V. , Higgins John P. , Sishc Brock J. , Nicolau Monica , Dorth Jennifer A. , Chernikova Diana A. , Kwok Shirley , Brooks James D. , Bailey Susan M. , Game John C. , Brown J. Martin
Published: March 2023

PDF file - 61K
Supplementary Materials and Methods from Deficiency in Mammalian Histone H2B Ubiquitin Ligase Bre1 (Rnf20/Rnf40) Leads to Replication Stress and Chromosomal Instability
Authors: Chernikova Sophia B. , Razorenova Olga V. , Higgins John P. , Sishc Brock J. , Nicolau Monica , Dorth Jennifer A. , Chernikova Diana A. , Kwok Shirley , Brooks James D. , Bailey Susan M. , Game John C. , Brown J. Martin
Published: March 2023

PDF file - 58K
Supplementary Figure Legends from SIRT1 Pathway Dysregulation in the Smoke-Exposed Airway Epithelium and Lung Tumor Tissue
Authors: Beane Jennifer , Cheng Luis , Soldi Raffaella , Zhang Xiaohui , Liu Gang , Anderlind Christina , Lenburg Marc E. , Spira Avrum , Bild Andrea H.
Published: March 2023

PDF file, 53K
Supplementary Figure Legends 1-4, Methods from Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression
Authors: Bobrie Angélique , Krumeich Sophie , Reyal Fabien , Recchi Chiara , Moita Luis F. , Seabra Miguel C. , Ostrowski Matias , Théry Clotilde
Published: March 2023

PDF file - 113K
Supplementary Figure Legends 1-4 from Targeting BRCA1 Localization to Augment Breast Tumor Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition
Authors: Yang Eddy S. , Nowsheen Somaira , Rahman Mohammad A. , Cook Rebecca S. , Xia Fen
Published: March 2023

PDF file - 93K
Supplementary Figures 1-2 from Comparison of Neuropathy-Inducing Effects of Eribulin Mesylate, Paclitaxel, and Ixabepilone in Mice
Authors: Wozniak Krystyna M. , Nomoto Kenichi , Lapidus Rena G. , Wu Ying , Carozzi Valentina , Cavaletti Guido , Hayakawa Kazuhiro , Hosokawa Satoru , Towle Murray J. , Littlefield Bruce A. , Slusher Barbara S.
Published: March 2023

Supplementary Figures 1-2 from Comparison of Neuropathy-Inducing Effects of Eribulin Mesylate, Paclitaxel, and Ixabepilone in Mice
Supplementary Figure Legends 1-2 from Comparison of Neuropathy-Inducing Effects of Eribulin Mesylate, Paclitaxel, and Ixabepilone in Mice
Authors: Wozniak Krystyna M. , Nomoto Kenichi , Lapidus Rena G. , Wu Ying , Carozzi Valentina , Cavaletti Guido , Hayakawa Kazuhiro , Hosokawa Satoru , Towle Murray J. , Littlefield Bruce A. , Slusher Barbara S.
Published: March 2023

Supplementary Figure Legends 1-2 from Comparison of Neuropathy-Inducing Effects of Eribulin Mesylate, Paclitaxel, and Ixabepilone in Mice
Supplementary Figures 1-10 from Immune-Dependent and Independent Antitumor Activity of GM-CSF Aberrantly Expressed by Mouse and Human Colorectal Tumors
Authors: Urdinguio Rocio G. , Fernandez Agustin F. , Moncada-Pazos Angela , Huidobro Covadonga , Rodriguez Ramon M. , Ferrero Cecilia , Martinez-Camblor Pablo , Obaya Alvaro J. , Bernal Teresa , Parra-Blanco Adolfo , Rodrigo Luis , Santacana Maria , Matias-Guiu Xavier , Soldevilla Beatriz , Dominguez Gemma , Bonilla Felix , Cal Santiago , Lopez-Otin Carlos , Fraga Mario F.
Published: March 2023

PDF file - 434K, (S1) GM-CSF expression and DNA methylation values at the GM-CSF promoter in human colon cancer cell lines; (S2) Association between LINE-1 and GM-CSF hypomethylation in human colon primary tumors; (S3) Characterization of mouse healthy colon (mHC), two murine colon cancer cell lines (MC38 and CT26), and the clones derived from Gm-CSf interference by stable transfection of those cell lines; (S4) Characterization of other independent clones derived from Gm-CSf interference by stable transfection of MC38 and CT26 cell lines and paracrine effects of Gm-CSf in vivo; (S5) Autocrine effects of Gm-CSf on tumor growth in vitro using an independent shRNA; (S6) Combination of autocrine and paracrine effects in vivo using an independent shRNA; (S7) Properties of wild-type MC38 cell line; (S8) Confocal representative images showing the expression of GM-CSF and its receptor in human colon primary tumors; (S9) Kaplan-Meier study of overall survival in 124 human paired colon samples; (S10) Published data of DNA methylation levels at the GM-CSF promoter and GM-CSF expression in human healthy primary samples.
Supplementary Tables 1-7 from Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with BRCA1/2 Inactivation
Authors: Popova Tatiana , Manié Elodie , Rieunier Guillaume , Caux-Moncoutier Virginie , Tirapo Carole , Dubois Thierry , Delattre Olivier , Sigal-Zafrani Brigitte , Bollet Marc , Longy Michel , Houdayer Claude , Sastre-Garau Xavier , Vincent-Salomon Anne , Stoppa-Lyonnet Dominique , Stern Marc-Henri
Published: March 2023

PDF file - 198K, Table S1. Number of chromosomes in the cell lines according to ATCC description, SKY images, and GAP estimation. Table S2. Tumor ploidy and percentage of genomic states in tumor genome. Table S3. Validation of LSTs by NGS, PCR and Sanger sequencing. Table S4. Final results obtained on the Experimental set of BLCs. Table S5. Final results obtained on the Validation set of BLCs. Table S6. LSTs fit validated rearrangements in triple-negative cell lines. Table S7. LSTs are conserved in xenografts.
Supplementary Figure 5 from Soluble CD200 Is Critical to Engraft Chronic Lymphocytic Leukemia Cells in Immunocompromised Mice
Authors: Wong Karrie K. , Brenneman Fred , Chesney Alden , Spaner David E. , Gorczynski Reginald M.
Published: March 2023

PDF file - 125K, Engraftment of CD19+CD5+ CLL cells in peritoneal cavity: CD19+CD5+ CLL cells within the CD45+ population in the peritoneal cavity of mice that received one of three plasma infusions: sCD200lo normal plasma (upper panel), sCD200hi CLL plasma (middle panel), or sCD200lo normal plasma + CD200Fc (lower panel). Representative data from individual animals from each group are shown
Supplementary Figure 4 from Soluble CD200 Is Critical to Engraft Chronic Lymphocytic Leukemia Cells in Immunocompromised Mice
Authors: Wong Karrie K. , Brenneman Fred , Chesney Alden , Spaner David E. , Gorczynski Reginald M.
Published: March 2023

PDF file - 66K, 6.Engraftment of CD19+CD5+ CLL cells in peritoneal cavity: Absolute count (x105 cells) of CD19+CD5+ CLL cells in the peritoneal cavity of animals receiving one of the three plasma infusions: sCD200hi CLL plasma, sCD200hi CLL plasma + anti-CD200 (Fab), or sCD200 absorbed CLL plasma
Supplementary Figure 3 from Soluble CD200 Is Critical to Engraft Chronic Lymphocytic Leukemia Cells in Immunocompromised Mice
Authors: Wong Karrie K. , Brenneman Fred , Chesney Alden , Spaner David E. , Gorczynski Reginald M.
Published: March 2023

PDF file - 137K, Engraftment of human CLL and T cells in murine bone marrow: Engraftment of human CD45+ cells in murine bone marrow (left column) at day 70 (Sp6) . Within the CD45+ population, the distribution of CD19+CD5+ CLL cells and T cells (CD4+ and CD8+) are shown in the middle and right column, respectively. CD19, CD5, CD5, and CD8 staining on engrafted cells is compared to that of the original cells used for engraftment from Sp6 (upper panel). FACS data from two representative animals are shown
Supplementary Figure 1 from RNF8 Regulates Assembly of RAD51 at DNA Double-Strand Breaks in the Absence of BRCA1 and 53BP1
Authors: Nakada Shinichiro , Yonamine Rikako Miyamoto , Matsuo Koichi
Published: March 2023

PDF file - 121K, A schematic of the assembly of DNA damage response-related proteins at DSB sites
Supplementary Figure 7 from Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors
Authors: Laurent Julien , Hull Eveline Faes-van't , Touvrey Cedric , Kuonen François , Lan Qiang , Lorusso Girieca , Doucey Marie-Agnès , Ciarloni Laura , Imaizumi Natsuko , Alghisi Gian Carlo , Fagiani Ernesta , Zaman Khalil , Stupp Roger , Shibuya Masabumi , Delaloye Jean-François , Christofori Gerhard , Ruegg Curzio
Published: March 2023

Supplementary Figure 7 from Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors
Supplementary Table S2 from LIN28B Polymorphisms Influence Susceptibility to Epithelial Ovarian Cancer
Authors: Permuth-Wey Jennifer , Kim Donghwa , Tsai Ya-Yu , Lin Hui-Yi , Chen Y. Ann , Barnholtz-Sloan Jill , Birrer Michael J. , Bloom Gregory , Chanock Stephen J. , Chen Zhihua , Cramer Daniel W. , Cunningham Julie M. , Dagne Getachew , Ebbert-Syfrett Judith , Fenstermacher David , Fridley Brooke L. , Garcia-Closas Montserrat , Gayther Simon A. , Ge William , Gentry-Maharaj Aleksandra , Gonzalez-Bosquet Jesus , Goode Ellen L. , Iversen Edwin , Jim Heather , Kong William , McLaughlin John , Menon Usha , Monteiro Alvaro N.A. , Narod Steven A. , Pharoah Paul D.P. , Phelan Catherine M. , Qu Xiaotao , Ramus Susan J. , Risch Harvey , Schildkraut Joellen M. , Song Honglin , Stockwell Heather , Sutphen Rebecca , Terry Kathryn L. , Tyrer Jonathan , Vierkant Robert A. , Wentzensen Nicolas , Lancaster Johnathan M. , Cheng Jin Q. , Sellers Thomas A.
Published: March 2023

Supplementary Table S2 from LIN28B Polymorphisms Influence Susceptibility to Epithelial Ovarian Cancer
Supplementary Figure 1 from Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors
Authors: Laurent Julien , Hull Eveline Faes-van't , Touvrey Cedric , Kuonen François , Lan Qiang , Lorusso Girieca , Doucey Marie-Agnès , Ciarloni Laura , Imaizumi Natsuko , Alghisi Gian Carlo , Fagiani Ernesta , Zaman Khalil , Stupp Roger , Shibuya Masabumi , Delaloye Jean-François , Christofori Gerhard , Ruegg Curzio
Published: March 2023

Supplementary Figure 1 from Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors
Supplementary Methods, Table 1, Figures 1-8 from Genetic Deficiency in Plasma Protein HRG Enhances Tumor Growth and Metastasis by Exacerbating Immune Escape and Vessel Abnormalization
Authors: Tugues Sònia , Honjo Satoshi , König Christian , Noguer Oriol , Hedlund Marie , Botling Johan , Deschoemaeker Sofie , Wenes Mathias , Rolny Charlotte , Jahnen-Dechent Wilhelm , Mazzone Massimiliano , Claesson-Welsh Lena
Published: March 2023

PDF file - 168K
Supplementary Figures Legends 1-2, Methods from S-Glutathionylated Serine Proteinase Inhibitors as Plasma Biomarkers in Assessing Response to Redox-Modulating Drugs
Authors: Grek Christina L. , Townsend Danyelle M. , Uys Joachim D. , Manevich Yefim , Coker Woodrow J. , Pazoles Christopher J. , Tew Kenneth D.
Published: March 2023

PDF file - 84K
Supplementary Movie 2 from Interstitial Fluid Pressure and Associated Lymph Node Metastasis Revealed in Tumors by Dynamic Contrast-Enhanced MRI
Authors: Hompland Tord , Ellingsen Christine , Øvrebø Kirsti Marie , Rofstad Einar K.
Published: March 2023

MOV file - 305K, Video showing the outward movement of the peritumoral high-signal-intensity rim of a human cervical carcinoma
Supplementary Figure 1 from S-Glutathionylated Serine Proteinase Inhibitors as Plasma Biomarkers in Assessing Response to Redox-Modulating Drugs
Authors: Grek Christina L. , Townsend Danyelle M. , Uys Joachim D. , Manevich Yefim , Coker Woodrow J. , Pazoles Christopher J. , Tew Kenneth D.
Published: March 2023

PDF file - 2.1MB
Supplementary Material from Inhibition of Tumor Cell Migration by LD22-4, an N-Terminal Fragment of 24-kDa FGF2, Is Mediated by Neuropilin 1
Authors: Zhang Ling , Parry Graham C. , Levin Eugene G.
Published: March 2023

Supplementary Material - PDF file 116K, This supplemental material contains the experimental details of the Binding Experiments, In vivo Analysis of LD22-4 Activity, and Cell Viability Assay
Supplementary Table 2 from Transition from Colitis to Cancer: High Wnt Activity Sustains the Tumor-Initiating Potential of Colon Cancer Stem Cell Precursors
Authors: Shenoy Anitha K. , Fisher Robert C. , Butterworth Elizabeth A. , Pi Liya , Chang Lung-Ji , Appelman Henry D. , Chang Myron , Scott Edward W. , Huang Emina H.
Published: March 2023

PDF file - 102K, Tumorigenic potential of Wnt(high) vs Wnt(low) cells derived from pCCSCs and CCSCs in primary passage
Supplementary Table 1 from Transition from Colitis to Cancer: High Wnt Activity Sustains the Tumor-Initiating Potential of Colon Cancer Stem Cell Precursors
Authors: Shenoy Anitha K. , Fisher Robert C. , Butterworth Elizabeth A. , Pi Liya , Chang Lung-Ji , Appelman Henry D. , Chang Myron , Scott Edward W. , Huang Emina H.
Published: March 2023

PDF file - 91K, Characteristics of patients from whom colon tissues were derived for immunostaining of beta-catenin and ALDH
Supplementary Materials and Methods from Gliomagenesis Arising from Pten- and Ink4a/Arf-Deficient Neural Progenitor Cells Is Mediated by the p53-Fbxw7/Cdc4 Pathway, Which Controls c-Myc
Authors: Kim Hong Sug , Woolard Kevin , Lai Chen , Bauer Peter O. , Maric Dragan , Song Hua , Li Aiguo , Kotliarova Svetlana , Zhang Wei , Fine Howard A.
Published: March 2023

PDF file, 117K
Supplementary Figure Legends 1-8 from Transition from Colitis to Cancer: High Wnt Activity Sustains the Tumor-Initiating Potential of Colon Cancer Stem Cell Precursors
Authors: Shenoy Anitha K. , Fisher Robert C. , Butterworth Elizabeth A. , Pi Liya , Chang Lung-Ji , Appelman Henry D. , Chang Myron , Scott Edward W. , Huang Emina H.
Published: March 2023

PDF file - 104K
Supplementary Figure 5 from Transition from Colitis to Cancer: High Wnt Activity Sustains the Tumor-Initiating Potential of Colon Cancer Stem Cell Precursors
Authors: Shenoy Anitha K. , Fisher Robert C. , Butterworth Elizabeth A. , Pi Liya , Chang Lung-Ji , Appelman Henry D. , Chang Myron , Scott Edward W. , Huang Emina H.
Published: March 2023

PDF file - 995K, Comparison of primary versus secondary Wnt(high) CT-2 tumor xenografts
Supplementary Figure 4 from Transition from Colitis to Cancer: High Wnt Activity Sustains the Tumor-Initiating Potential of Colon Cancer Stem Cell Precursors
Authors: Shenoy Anitha K. , Fisher Robert C. , Butterworth Elizabeth A. , Pi Liya , Chang Lung-Ji , Appelman Henry D. , Chang Myron , Scott Edward W. , Huang Emina H.
Published: March 2023

PDF file - 2MB, Wnt activity in ALDH(high)-Wnt(high) and ALDH(high)-Wnt(low) primary tumor xenografts (1o)
Supplementary Figure 3 from Transition from Colitis to Cancer: High Wnt Activity Sustains the Tumor-Initiating Potential of Colon Cancer Stem Cell Precursors
Authors: Shenoy Anitha K. , Fisher Robert C. , Butterworth Elizabeth A. , Pi Liya , Chang Lung-Ji , Appelman Henry D. , Chang Myron , Scott Edward W. , Huang Emina H.
Published: March 2023

PDF file - 66K, Validation of Wnt/beta-catenin reporter in CT-1 pCCSCs
Supplementary Figure 2 from Transition from Colitis to Cancer: High Wnt Activity Sustains the Tumor-Initiating Potential of Colon Cancer Stem Cell Precursors
Authors: Shenoy Anitha K. , Fisher Robert C. , Butterworth Elizabeth A. , Pi Liya , Chang Lung-Ji , Appelman Henry D. , Chang Myron , Scott Edward W. , Huang Emina H.
Published: March 2023

PDF file - 1.2MB, FACS profile and experimental overview
Supplementary Figure 1 from Transition from Colitis to Cancer: High Wnt Activity Sustains the Tumor-Initiating Potential of Colon Cancer Stem Cell Precursors
Authors: Shenoy Anitha K. , Fisher Robert C. , Butterworth Elizabeth A. , Pi Liya , Chang Lung-Ji , Appelman Henry D. , Chang Myron , Scott Edward W. , Huang Emina H.
Published: March 2023

PDF file - 3.7MB, Levels of Wnt/beta-catenin signaling in normal, colitis and CRC colons
Supplementary Table 2 from Lymphatic Reprogramming by Kaposi Sarcoma Herpes Virus Promotes the Oncogenic Activity of the Virus-Encoded G-protein–Coupled Receptor
Authors: Aguilar Berenice , Choi Inho , Choi Dongwon , Chung Hee Kyoung , Lee Sunju , Yoo Jaehyuk , Lee Yong Suk , Maeng Yong Sun , Lee Ha Neul , Park Eunkyung , Kim Kyu Eui , Kim Nam Yoon , Baik Jae Myung , Jung Jae U. , Koh Chester J. , Hong Young-Kwon
Published: March 2023

PDF file - 65K, Regulation of the expression of various nuclear receptors by KSHV in BECs
Supplementary Table 1 from Neuropilin-1 Identifies a Subset of Bone Marrow Gr1− Monocytes That Can Induce Tumor Vessel Normalization and Inhibit Tumor Growth
Authors: Carrer Alessandro , Moimas Silvia , Zacchigna Serena , Pattarini Lucia , Zentilin Lorena , Ruozi Giulia , Mano Miguel , Sinigaglia Milena , Maione Federica , Serini Guido , Giraudo Enrico , Bussolino Federico , Giacca Mauro
Published: March 2023

PDF file - 91K, Supplementary Table 1. List of genes analyzed for expression by real-time, quantitative RT-PCR. All the amplifications were performed on a 7000 ABI Prism Instrument (Applied Biosystems), using pre-developed assays ("Mm" code), custom assays (for CCL5 and CXCR4) (Applied Biosystems) or SYBR Green (for Gr-1 and HPRT). The housekeeping genes GAPDH and HPRT were used to normalize the results.
Supplementary Figure 2 from Neuropilin-1 Identifies a Subset of Bone Marrow Gr1− Monocytes That Can Induce Tumor Vessel Normalization and Inhibit Tumor Growth
Authors: Carrer Alessandro , Moimas Silvia , Zacchigna Serena , Pattarini Lucia , Zentilin Lorena , Ruozi Giulia , Mano Miguel , Sinigaglia Milena , Maione Federica , Serini Guido , Giraudo Enrico , Bussolino Federico , Giacca Mauro
Published: March 2023

PDF file - 3108K, Flow cytometry analysis of NEMs purified from the bone marrow. Flow cytometry analysis of bone marrow CD11b+/Gr1-/Nrp1+ cells (NEMs) using the indicated antibodies conjugated with phycoerythrin (PE). Percentages of positive cells, referred to the total number of NEMs, are reported. The plots reported in the first row are also shown in Figure 1D, fourth column.
Supplementary Figure 3 from Tumor Vascular Microenvironment Determines Responsiveness to Photodynamic Therapy
Authors: Maas Amanda L. , Carter Shirron L. , Wileyto E. Paul , Miller Joann , Yuan Min , Yu Guoqiang , Durham Amy C. , Busch Theresa M.
Published: March 2023

PDF file - 2.6MB
Supplementary Figure 1 from Neuropilin-1 Identifies a Subset of Bone Marrow Gr1− Monocytes That Can Induce Tumor Vessel Normalization and Inhibit Tumor Growth
Authors: Carrer Alessandro , Moimas Silvia , Zacchigna Serena , Pattarini Lucia , Zentilin Lorena , Ruozi Giulia , Mano Miguel , Sinigaglia Milena , Maione Federica , Serini Guido , Giraudo Enrico , Bussolino Federico , Giacca Mauro
Published: March 2023

PDF file - 1560K, Quantification of the flow cytometry profiles for the characterization of the four bone marrow cell populations sorted according to the expression of Nrp1 and Gr1. The results (shown as bar charts in the upper part of the figure and as a table in the bottom part) refer to four independent experiments; shown are the mean � s.d. The markers analyzed are the same as in the representative experiment shown in Figure 1D.
Supplementary Figure Legends from PML-RARα and Its Phosphorylation Regulate PML Oligomerization and HIPK2 Stability
Authors: Shima Yutaka , Honma Yuki , Kitabayashi Issay
Published: March 2023

PDF - 80K, Legend for Supplementary Figures S1-S6
Supplementary Figures 1-6, Methods from The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion
Authors: Koh Mei Yee , Lemos Robert , Liu Xiuping , Powis Garth
Published: March 2023

Supplementary Figures 1-6, Methods from The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion
Supplementary Figure Legend from Aptamer Identification of Brain Tumor–Initiating Cells
Authors: Kim Youngmi , Wu Qiulian , Hamerlik Petra , Hitomi Masahiro , Sloan Andrew E. , Barnett Gene H. , Weil Robert J. , Leahy Patrick , Hjelmeland Anita B. , Rich Jeremy N.
Published: March 2023

PDF file - 61K
Supplementary Figure 3 from Endoneurial Macrophages Induce Perineural Invasion of Pancreatic Cancer Cells by Secretion of GDNF and Activation of RET Tyrosine Kinase Receptor
Authors: Cavel Oren , Shomron Olga , Shabtay Ayelet , Vital Joseph , Trejo-Leider Leonor , Weizman Noam , Krelin Yakov , Fong Yuman , Wong Richard J. , Amit Moran , Gil Ziv
Published: March 2023

PDF file - 178K, Scratch assays of MiaPaCa2 cells in the presence or absence of EMPhi-CM. (a) Representative pictures taken after 24 and 48 hours showing increased motility of cancer cells incubated with EMPhi-CM (lower row) relative to normal medium (DMEM- upper row). (b) Summary of the data showing statistically significant increase in cancer cell motility after incubation in EMPhi-CM compared to normal media (n=6, P<0.001).
Supplementary Figure Legend from Host Immune Defense Peptide LL-37 Activates Caspase-Independent Apoptosis and Suppresses Colon Cancer
Authors: Ren Shun X. , Cheng Alfred S.L. , To Ka F. , Tong Joanna H.M. , Li May S. , Shen Jin , Wong Clover C.M. , Zhang Lin , Chan Ruby L.Y. , Wang Xiao J. , Ng Simon S.M. , Chiu Lawrence C.M. , Marquez Victor E. , Gallo Richard L. , Chan Francis K.L. , Yu Jun , Sung Joseph J.Y. , Wu William K.K. , Cho Chi H.
Published: March 2023

PDF file - 58K
Supplementary Table 1 from TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells
Authors: Weiss Michele B. , Abel Ethan V. , Mayberry Melanie M. , Basile Kevin J. , Berger Adam C. , Aplin Andrew E.
Published: March 2023

PDF file - 2984K, Oligonucleotide and primer sequences