bluuebunny/crossref_metadata_2025 huggingface dataset:
Music Therapy Assessment for Older Adults: Descriptive Mixed-Methods Study
Authors: Clements-Cortés Amy
Published: April 2024

Background: The purpose of this inquiry was to test the new ‘Music Therapy Assessment for Older Adults’ (MTAOA) tool in Canada and the United States, and to establish its content and predictive utility. Methods: A pilot study using an explanatory descriptive methods design was chosen; n = 18 music therapists completed an online survey about their experiences in administering the assessment and 50% (n = 9) were invited for a follow-up interview. Results: The results indicated that the MTAOA was a beneficial assessment tool that contained relevant domains (89%) to develop a music therapy treatment plan; 89% of music therapists also noted they would continue to use and recommend the MTAOA. The data produced beneficial information that were used to revise the assessment form to ensure inclusive language and reduce any potential inherent or unconscious biases. Conclusions: Future research is needed to assess the utility of the revised MTAOA in other global regions where music therapists work with older adults.
Catalytic Epoxidation Reaction
Authors: Leveneur Sébastien , Tolvanen Pasi , Russo Vincenzo
Published: April 2024

The epoxidation of unsaturated groups is a well-known process [...]
Copper Homeostasis in the Model Organism C. elegans
Authors: Ohse Verena Alexia , Klotz Lars-Oliver , Priebs Josephine
Published: April 2024

Cellular and organismic copper (Cu) homeostasis is regulated by Cu transporters and Cu chaperones to ensure the controlled uptake, distribution and export of Cu ions. Many of these processes have been extensively investigated in mammalian cell culture, as well as in humans and in mammalian model organisms. Most of the human genes encoding proteins involved in Cu homeostasis have orthologs in the model organism, Caenorhabditis elegans (C. elegans). Starting with a compilation of human Cu proteins and their orthologs, this review presents an overview of Cu homeostasis in C. elegans, comparing it to the human system, thereby establishing the basis for an assessment of the suitability of C. elegans as a model to answer mechanistic questions relating to human Cu homeostasis.
Pin1-Catalyzed Conformation Changes Regulate Protein Ubiquitination and Degradation
Authors: Jeong Jessica , Usman Muhammad , Li Yitong , Zhou Xiao Zhen , Lu Kun Ping
Published: April 2024

The unique prolyl isomerase Pin1 binds to and catalyzes cis–trans conformational changes of specific Ser/Thr-Pro motifs after phosphorylation, thereby playing a pivotal role in regulating the structure and function of its protein substrates. In particular, Pin1 activity regulates the affinity of a substrate for E3 ubiquitin ligases, thereby modulating the turnover of a subset of proteins and coordinating their activities after phosphorylation in both physiological and disease states. In this review, we highlight recent advancements in Pin1-regulated ubiquitination in the context of cancer and neurodegenerative disease. Specifically, Pin1 promotes cancer progression by increasing the stabilities of numerous oncoproteins and decreasing the stabilities of many tumor suppressors. Meanwhile, Pin1 plays a critical role in different neurodegenerative disorders via the regulation of protein turnover. Finally, we propose a novel therapeutic approach wherein the ubiquitin–proteasome system can be leveraged for therapy by targeting pathogenic intracellular targets for TRIM21-dependent degradation using stereospecific antibodies.
Climate Change in Rural Australia: Natural Hazard Preparedness and Recovery Needs of a Rural Community
Authors: Pike Caitlin E. , Lykins Amy D. , Bartik Warren , Tully Phillip J. , Cosh Suzanne M.
Published: April 2024

Climate change has resulted in a worldwide increase in intensity and frequency of extreme weather events including bushfires. Previous research has shown that communities often do not engage in disaster preparedness, even when sufficient education and resources are provided. With the projected increase in natural disasters, preparedness is paramount, and more research is needed to gain an understanding into what impacts community preparedness in the face of climate change. This study investigated one rural Australian community’s preparedness for the 2019–2020 bushfires. Thirteen Australian adults who resided within a small rural community in New South Wales during the 2019–2020 bushfires participated in semi-structured interviews. Data were analysed using inductive thematic analysis. Participants reported being unprepared for the 2019–2020 bushfires and that the community has started to prepare for future bushfires. However, they also described a belief in ‘climate cycles’ rather than climate change, limiting engagement in preparedness for future hazards. Participants also reported that they did not talk about the 2019–2020 bushfires, although described experiencing residual anxiety. Recommendations included support needed for rural communities to help with future preparedness efforts and mental health symptoms.
A Worldwide Bibliometric Analysis of Published Literature Assessing Fear of COVID-19
Authors: Cebrino Jesús , Portero de la Cruz Silvia
Published: April 2024

Many people experience intense fear of COVID-19. The purpose of this study was to provide a comprehensive visual overview of the published literature from 2020 to 2022 assessing fear of COVID-19. From 2020 to 2022, we employed the Scopus database to conduct a bibliometric analysis. We used the VOSviewer program to perform the author co-citation analysis, Mapchart to produce a worldwide map, and Wordart to make a word cloud image. From the 1769 records examined, 1654 (93.50%) were articles, with English being the most common language (96.31%). From 2020 to 2022, annual citations experienced significant growth (R2 = 99.91%; p = 0.0195). The Institut National de la Santé et de la Recherche Médicale (INSERM, France) and China led in terms of publication output (n = 36; n = 255). M. D. Griffiths authored the highest number of articles (n = 21). The most active journal was the International Journal of Environmental Research and Public Health (n = 146), and the most prevalent keyword was “human/s” (11.51%). This bibliometric analysis evaluates the quality of the research on fear of the pandemic and the crisis management of COVID-19, which can provide managers and researchers with crucial insights for future decision making.
Manufacture of Microstructured Optical Fibers: Problem of Optimal Control of Silica Capillary Drawing Process
Authors: Vladimirova Daria , Pervadchuk Vladimir , Konstantinov Yuri
Published: April 2024

The effective control of any technological process is essential in ensuring high-quality finished products. This is particularly true in manufacturing knowledge-intensive and high-tech products, including microstructured photonic crystal fibers (PCF). This paper addresses the issues of stabilizing the optimal control of the silica capillary drawing process. The silica capillaries are the main components of PCF. A modified mathematical model proposed by the authors is used as the basic model of capillary drawing. The uniqueness of this model is that it takes into account the main forces acting during drawing (gravity, inertia, viscosity, surface tension, pressure inside the drawn capillary), as well as all types of heat transfer (heat conduction, convection, radiation). In the first stage, the system of partial differential equations describing heat and mass transfer was linearized. Then, the problem of the optimal control of the drawing process was formulated, and optimization systems for the isothermal and non-isothermal cases were obtained. In the isothermal case, optimal adjustments of the drawing speed were obtained for different objective functionals. Thus, the proposed approach allows for the constant monitoring and adjustment of the observed state parameters (for example, the outer radius of the capillary). This is possible due to the optimal control of the drawing speed to obtain high-quality preforms. The ability to control and promptly eliminate geometric defects in the capillary was confirmed by the analysis of the numerical calculations, according to which even 15% deviations in the outer radius of the capillary during the drawing process can be reduced to 4–5% by controlling only the capillary drawing speed.
BEM Modeling for Stress Sensitivity of Nonlocal Thermo-Elasto-Plastic Damage Problems
Authors: Fahmy Mohamed Abdelsabour
Published: April 2024

The main objective of this paper is to propose a new boundary element method (BEM) modeling for stress sensitivity of nonlocal thermo-elasto-plastic damage problems. The numerical solution of the heat conduction equation subjected to a non-local condition is described using a boundary element model. The total amount of heat energy contained inside the solid under consideration is specified by the non-local condition. The procedure of solving the heat equation will reveal an unknown control function that governs the temperature on a specific region of the solid’s boundary. The initial stress BEM for structures with strain-softening damage is employed in a boundary element program with iterations in each load increment to develop a plasticity model with yield limit deterioration. To avoid the difficulties associated with the numerical calculation of singular integrals, the regularization technique is applicable to integral operators. To validate the physical correctness and efficiency of the suggested formulation, a numerical case is solved.
III-Nitride Materials: Properties, Growth, and Applications
Authors: Li Yangfeng
Published: April 2024

Since the activation of magnesium (Mg) in p-type gallium nitride (GaN) [...]
Comparison of Functional Outcomes after Anterior Cruciate Ligament Reconstruction with Meniscal Repair for Unstable versus Stable Meniscal Tears
Authors: Lee Jin , Lee Gyu , Chung Woo Yong , Wang Ji , Han Sun , Rhim Hye , Han Seung-Beom , Jang Ki-Mo
Published: April 2024

This study aimed to compare functional outcomes including knee muscle strength in the quadriceps and hamstrings, and proprioception, assessed through dynamic postural stability (overall stability index [OSI]) and self-reported outcomes in the operated and non-operated knees between anterior cruciate ligament reconstruction (ACLR) with meniscal repair for unstable (root and radial tears) and stable (longitudinal, horizontal, and bucket handle tears) meniscal tears. A total of 76 patients were randomly selected (41 with ACLR with meniscal repair for unstable meniscal tears and 35 with ACLR with meniscal repair for stable meniscal tears) at three different time points (preoperative, 6 months, and 12 months). Repeated measures analysis of variance was used to investigate the differences in outcomes for between-subject and within-subject factors. In the operated knees, there were no significant differences for functional outcomes between the two groups (all p > 0.05). In the non-operated knees, a significant difference was observed for the OSI between the two groups, which was significantly higher in ACLR with meniscal repair for unstable meniscal tears than for stable meniscal tears at 6 months (p < 0.001). Multiple linear regression analysis showed that age (p = 0.027), preoperative OSI in the operated knees (p = 0.005), and postoperative OSI in the operated knees at 6 months (p = 0.002) were significant and independent predictors for OSI in the non-operated knees at 6 months postoperatively. Therefore, while no differences were observed in functional outcomes between the two groups in the operated knees, dynamic postural stability was poorer at 6 months postoperatively in the non-operated knees of patients with ACLR with meniscal repair for unstable meniscal tears. Furthermore, a significant correlation was observed between preoperative/postoperative dynamic postural stability in the operated knees and postoperative dynamic postural stability in the non-operated knees. Hence, we recommend incorporating balance exercises for both knees in post-surgical rehabilitation, particularly for patients with unstable meniscal tears.
Cultivating Professional Identity: The Vital Role of Practical Teaching Experience for Future Educators
Authors: Simon Eitan
Published: April 2024

This article endeavors to investigate the impact of three years of teaching experience acquired during student teaching training on the professional identity of aspiring educators. The ensuing literature review expounds upon the concepts of identity and professional identity. To scrutinize this subject comprehensively, a quantitative study was conducted, the details of which are elucidated in the subsequent section devoted to research methodology. The findings of this study underscore the paramount significance of fostering a sense of belonging and mission as integral components that underpin the means of support, adaptability, and PI development, particularly pertinent to student teachers and, especially, those immersed in the practical experience phase, as discerned through their self-perceptions. The principal conclusions and insights drawn from the cumulative body of research evidence underscore that, despite the recent recognition accorded the pedagogical training processes and their multifaceted impact on various aspects of a student’s life as a future educator, the teaching profession still remains underappreciated. The finding that emerged during this study underscores the heightened significance of teaching practices as an essential element in the preparation of a prospective graduate who aspires to become a pioneering educator in shaping the future of generations to come. The investigation surveyed 216 students pursuing teaching degrees, analyzing their professional identity development throughout their academic journey. Results revealed a positive association between the students’ advancement in their training curriculum and the enhancement of their professional identity. Specifically, as students progressed further in their studies, there was a discernible growth in their identification with the teaching profession.
Random Numbers Generated Based on Dual-Channel Chaotic Light
Authors: Liu Guopeng , Mu Penghua , Wang Kun , Guo Gang , Liu Xintian , He Pengfei
Published: April 2024

This paper presents a chaotic system based on novel semiconductor nanolasers (NLs), systematically analyzing its chaotic region and investigating the influence of key parameters on the unpredictability of chaotic output. This study found that under optical feedback conditions, NLs generate chaos across a wide range of feedback parameters, with the highly unpredictable region completely overlapping with the chaotic region. Further injection into the slave lasers enhances the chaotic output, expanding the range of unpredictability. Additionally, we analyzed the impact of internal parameter mismatch on the complexity of chaotic signals and found it to be similar to the scenario when parameters are matched. Using this chaotic system as an entropy source, we constructed a random number generator (RNG) and investigated the effects of internal parameters mismatch and differences in the injection parameters on the generator’s performance. The simulation results show that the RNG performs well under different parameter settings, and the generated random sequences pass all random number tests successfully. Therefore, this chaotic system can yield a high-complexity chaotic light source with appropriate parameter selection, and when combined with effective post-processing, it can generate high-quality random numbers. This is crucial for advancing the realization of small-sized, high-randomness RNGs.
Be Cool: A Holistic and Innovative Approach to Rehabilitation in Multiple Sclerosis: Study Protocol for a Randomized Controlled Trial
Authors: Kaltsatou Antonia , Theodorou Sofia , Orologas Anastasios
Published: April 2024

(1) Background: Individuals with multiple sclerosis (MS) have to deal with numerous symptoms that adversely impact their quality of life. While pharmaceutical treatments offer some relief, they often fall short of addressing the full spectrum of MS symptoms. To bridge this gap, we introduce the Be Cool rehabilitation program, a comprehensive protocol designed to enhance the well-being and life quality of MS individuals. (2) Methods: The Be Cool program is a multifaceted approach that combines exercise training, nutritional guidance, psychological support, and cooling strategies. Adapted to meet the unique needs of MS individuals, this program aims to mitigate symptoms, promote physical and mental health, and improve overall quality of life. The integration of these strategies addresses the complex challenges faced by MS individuals, offering a holistic solution beyond conventional medication. (3) Conclusions: The Be Cool rehabilitation protocol is designed to offer individuals with MS a comprehensive approach to symptom management, fostering improvements in their quality of life. By addressing the multifaceted nature of MS through an integrated strategy, the program holds promise for more effective management of the condition.
Impact of a Rounding Checklist Implementation in the Trauma Intensive Care Unit on Clinical Outcomes
Authors: Seo Dongmin , Heo Inhae , Moon Jonghwan , Kwon Junsik , Huh Yo , Kang Byunghee , Song Seoyoung , Kim Sora , Jung Kyoungwon
Published: April 2024

We aimed to evaluate the effectiveness of an intensive care unit (ICU) round checklist, FAST HUGS BID (Feeding, Analgesia, Sedation, Thromboembolic prophylaxis, Head-of-bed elevation, Ulcer prophylaxis, Glycemic control, Spontaneous breathing trial, Bowel regimen, Indwelling catheter removal, and De-escalation of antibiotics—abbreviated as FD hereafter), in improving clinical outcomes in patients with severe trauma. We included patients admitted to our trauma ICU from 2016 to 2020 and divided them into two groups: before (before-FD, 2016–2017) and after (after-FD, 2019–2020) implementation of the checklist. We compared patient characteristics and clinical outcomes, including ICU and hospital length of stay (LOS) and in-hospital mortality. Survival analysis was performed using Kaplan–Meier curves and multivariable logistic regression models; furthermore, multiple linear regression analysis was used to identify independent factors associated with ICU and hospital LOS. Compared with the before-FD group, the after-FD group had significantly lower in-hospital mortality and complication rates, shorter ICU and hospital LOS, and reduced duration of mechanical ventilation. Moreover, implementation of the checklist was a significant independent factor in reducing ICU and hospital LOS and in-hospital mortality. Implementation of the FD checklist is associated with decreased ICU and hospital LOS and in-hospital mortality.
Comprehensive Equilibrium Function Tests for an Accurate Diagnosis in Vertigo: A Retrospective Analysis
Authors: Futami Shumpei , Miwa Toru
Published: April 2024

Background/Objectives: An accurate diagnosis of vertigo is crucial in patient care. Traditional balance function tests often fail to offer independent, conclusive diagnoses. This study aimed to bridge the gap between traditional diagnostic approaches and the evolving landscape of automated diagnostic tools, laying the groundwork for advancements in vertigo care. Methods: A cohort of 1400 individuals with dizziness underwent a battery of equilibrium function tests, and diagnoses were established based on the criteria by the Japanese Society for Vertigo and Equilibrium. A multivariate analysis identified the key diagnostic factors for various vestibudata nlar disorders, including Meniere’s disease, vestibular neuritis, and benign paroxysmal positional vertigo. Results: This study underscored the complexity of diagnosing certain disorders such as benign paroxysmal positional vertigo, where clinical symptoms play a crucial role. Additionally, it highlighted the utility of specific physical balance function tests for differentiating central diseases. These findings bolster the reliability of established diagnostic tools, such as audiometry for Meniere’s disease and spontaneous nystagmus for vestibular neuritis. Conclusions: This study concluded that a multifaceted approach integrating multiple diagnostic indicators is crucial for accurate clinical decisions in vestibular disorders. Future studies should incorporate novel tests, quantitative assessments, and advanced technologies to enhance the diagnostic capabilities of vestibular medicine.
Coagulation Tests and Reversal Agents in Patients Treated with Oral Anticoagulants: The Challenging Scenarios of Life-Threatening Bleeding and Unplanned Invasive Procedures
Authors: Pozzi Andrea , Lucà Fabiana , Gelsomino Sandro , Abrignani Maurizio Giuseppe , Giubilato Simona , Di Fusco Stefania Angela , Rao Carmelo Massimiliano , Cornara Stefano , Caretta Giorgio , Ceravolo Roberto , Parrini Iris , Geraci Giovanna , Riccio Carmine , Grimaldi Massimo , Colivicchi Furio , Oliva Fabrizio , Gulizia Michele Massimo
Published: April 2024

In clinical practice, the number of patients treated with direct oral anticoagulants (DOACs) has consistently increased over the years. Since anticoagulant therapy has been associated with an annual incidence of major bleeding (MB) events of approximately 2% to 3.5%, it is of paramount importance to understand how to manage anticoagulated patients with major or life-threatening bleeding. A considerable number of these patients’ conditions necessitate hospitalization, and the administration of reversal agents may be imperative to manage and control bleeding episodes effectively. Importantly, effective strategies for reversing the anticoagulant effects of DOACs have been well recognized. Specifically, idarucizumab has obtained regulatory approval for the reversal of dabigatran, and andexanet alfa has recently been approved for reversing the effects of apixaban or rivaroxaban in patients experiencing life-threatening or uncontrolled bleeding events. Moreover, continuous endeavors are being made to develop supplementary reversal agents. In emergency scenarios where specific reversal agents might not be accessible, non-specific hemostatic agents such as prothrombin complex concentrate can be utilized to neutralize the anticoagulant effects of DOACs. However, it is paramount to emphasize that specific reversal agents, characterized by their efficacy and safety, should be the preferred choice when suitable. Moreover, it is worth noting that adherence to the guidelines for the reversal agents is poor, and there is a notable gap between international recommendations and actual clinical practices in this regard. This narrative review aims to provide physicians with a practical approach to managing specific reversal agents.
Editorial for Special Issue: “Current and Emerging Therapies for Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia”
Authors: Savvides Eliophotos , Langas Georgios , Sountoulides Petros
Published: April 2024

Lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH) constitute a significant health concern worldwide, particularly among aging male populations [...]
Biologics and Non-Biologics Immunosuppressive Treatments for IgA Nephropathy in Both Adults and Children
Authors: Chiarenza Decimo Silvio , Verrina Enrico Eugenio , La Porta Edoardo , Caridi Gianluca , Ghiggeri Gian Marco , Mortari Gabriele , Lugani Francesca , Angeletti Andrea , Bigatti Carolina
Published: April 2024

Immunoglobulin A nephropathy represents the most prevalent cause of glomerulonephritis worldwide and may lead to renal failure in a relevant number of cases in both paediatric and adult subjects. Although their pathogenesis is still largely unclear, evidence of immune abnormalities provides the background for the use of immunosuppressive drugs, such as corticosteroids, calcineurin inhibitors, and antiproliferative and alkylating agents. Unfortunately, these treatments fail to achieve a sustained remission in a significant percentage of affected patients and are burdened by significant toxicities. Recent developments of new biologics, including anti-BAFF/APRIL inhibitors and molecules targeting complement components, offered the opportunity to selectively target immune cell subsets or activation pathways, leading to more effective and safer hypothesis-driven treatments. However, studies testing new biologic agents in IgAN should also consider paediatric populations to address the unique needs of children and close the therapeutic gap between adult and paediatric care.
Efficacy of Single- and Dual-Docking Robotic Surgery of Paraaortic and Pelvic Lymphadenectomy in High-Risk Endometrial Cancer
Authors: Bizoń Magdalena , Olszewski Maciej , Grabowska Agnieszka , Siudek Joanna , Mawlichanów Krzysztof , Pilka Radovan
Published: April 2024

(1) The surgical method of choice for the treatment of endometrial cancer is minimally invasive surgery. In cases of high-risk endometrial cancer, completed paraaortic and pelvic lymphadenectomy are indicated. The aim of this study was to analyze the types of docking during robotic surgery assisted with the da Vinci X system while performing paraaortic and pelvic lymphadenectomy. (2) Methods: A total of 25 patients with high-risk endometrial cancer, with a mean age of 60.07 ± 10.67 (range 34.69–83.23) years, and with a mean body mass index (BMI) of 28.4 ± 5.62 (range 18–41.5) kg/m2, were included in this study. The analyzed population was divided into groups that underwent single or dual docking during surgery. (3) Results: No statistical significance was observed between single and dual docking during paraaortic and pelvic lymphadenectomy and between the type of docking and the duration of the operation. However, there was a statistically significant correlation between the duration of the operation and previous surgery (p < 0.005). The number of removed lymph nodes was statistically associated with BMI (p < 0.005): 15.87 ± 6.83 and 24.5 ± 8.7 for paraaortic and pelvic lymph nodes, respectively, in cases of single docking, and 18.05 ± 7.92 and 24.88 ± 11.75 for paraaortic and pelvic lymph nodes, respectively, in cases of dual docking. (4) Conclusions: The robot-assisted approach is a good surgical method for lymphadenectomy for obese patients, and, despite the type of docking, there are no differences in the quality of surgery.
Impact of Water Management Policies on Volatility Transmission in the Energy Sector
Authors: Gormus Elif , Harrell Katharine
Published: April 2024

Purpose: This study evaluates the impact of the water management policies of energy companies on their volatility interactions with energy commodities. Design/methodology: We tested for volatility transmissions between 66 energy funds and fossil-fuel commodities. After identifying possible integrations, we investigated whether water management policies, after controlling for other fund characteristics, impact the probability of integration. Results: Our findings indicate strong volatility transmission from oil prices to energy funds. However, a reverse of this information flow was not observed. From the perspective of natural gas, we found strong bi-directional integration with energy funds. When we analyzed the influence of fund characteristics on the previously established integrations, water management policies do not impact the probability of the integration of oil. However, these policies are shown to have a significant influence on integration with the natural gas market. Originality/value: While there are multiple studies that show the integration between energy companies and corresponding commodities, according to our knowledge, this is the first study that evaluates the significance of water management policies with respect to volatility integration. This study highlights the importance of water-related policies with respect to the susceptibility of energy firms to volatility contagion from the natural gas market.
Land Cover Dynamics in the Northwestern Virunga Landscape: An Analysis of the Past Two Decades in a Dynamic Economic and Security Context
Authors: Musavandalo Charles Mumbere , Sambieni Kouagou Raoul , Mweru Jean-Pierre Mate , Bastin Jean-François , Ndukura Chantale Shalukoma , Nguba Timothée Besisa , Balandi Julien Bwazani , Bogaert Jan
Published: April 2024

The Beni region in the eastern Democratic Republic of Congo is grappling with socioeconomic development and security challenges that have affected its natural ecosystems, especially those located in the northern Virunga National Park. This study aims to document the anthropization of the northwestern Virunga landscape from 1995 to 2021 in the context of insecurity. Using a cartographic approach and ecological-landscape-analysis tools, this study delves into the overall landscape changes through a comparative analysis of protected and unprotected areas. These investigations focus on landscape composition, transitions between land-cover classes, and the spatial transformation process. The northwestern Virunga landscape is undergoing significant land cover changes due to the influence of insecurity on socioeconomic activities, primarily agriculture. Agricultural land encompasses a larger area than other land-cover types. However, its expansion has decelerated since the 2000s. The loss of forested area is discontinuous. During relatively stable periods (1995–2005), forests exhibited a reduction of up to 2.90% in area, while in the period of the return of Iturian refugees to their province, followed by terrorist insecurity in Beni (2005–2021), the forested area increased by 2.07%. Savannah areas, which are mainly located in the graben rift valley and near Butembo, have been more heavily affected by human activity than forests. Ultimately, the apparent stability of the landscape can be attributed to its protected areas, especially Virunga National Park.
Vibration-Based Detection of Axlebox Bearing Considering Inner and Outer Ring Raceway Defects
Authors: Liu Chuang , Zhang Xinwen , Wang Ruichen , Guo Qiang , Li Junguo
Published: April 2024

The occurrence of an axlebox bearing ring raceway defect is an inevitable and commonly observed phenomenon in railway wheels. It not only leads to surface damage but also poses the potential threat of further damage and degradation, thereby increasing the risks associated with running safety and maintenance costs. Hence, it becomes imperative to detect raceway defects at an early stage to mitigate safety hazards and reduce maintenance efforts. In this study, the focus lies in investigating the effectiveness of vibration-based detection techniques for identifying raceway defects in high-speed train axlebox bearing systems. To achieve this, a dynamic model that accurately represents the coupling dynamics between the vehicle and the track is developed. This model incorporates various dynamic factors, such as traction transmission, gear transmission, and track geometry irregularities. By using the comprehensive dynamic model, the dynamic responses of the axlebox can be accurately calculated. The proposed methodology primarily revolves around analysing the vertical vibrations of the axlebox caused by raceway defects in both the time and frequency domains. Additionally, an envelope analysis using a developed band-pass filter is also employed. The results obtained from this study clearly demonstrate the successful detection of raceway defects in a more realistic vehicle model, thereby providing an efficient approach for the detection of axlebox bearing raceway defects. Consequently, this research contributes significantly to the field of high-speed train systems and paves the way for enhanced safety and maintenance practices.
Research on Hydrogen-Induced Induced Cracking Sensitivity of X80 Pipeline Steel under Different Heat Treatments
Authors: Wu Chen , Yan Chunyan , Zhang Shenglin , Zhou Lingchuan , Shen Mengdie , Tian Zhanpeng
Published: April 2024

X80 pipeline steel has played a vital role in oil and gas transportation in recent years. However, hydrogen-related issues frequently lead to pipeline failures during service, resulting in significant losses of properties and lives. Three heat treatment processes (furnace cooling (FC), air cooling (AC), and water cooling (WC)) were carried out to investigate the effect of different microstructures on hydrogen-induced cracking (HIC) susceptibility of X80 pipeline steel. The WC sample demonstrated the highest hydrogen embrittlement index, registering at 21.9%, while the AC and FC samples exhibited progressively lower values of 15.45% and 10.98%, respectively. Under equivalent hydrogen charging durations, crack dimensions with a maximum length exceeding 30 μm in the WC sample generally exceed those in the FC sample and AC sample. The variation is attributed to the difference in microstructures of the samples, predominantly lath bainite (LB) in water-cooled samples, granular bainite (GB) in air-cooled samples, and ferrite/pearlite (F/P) in FC samples. The research results demonstrate that the sensitivity of lath bainite (LB) to HIC is significantly higher than that of pearlite, ferrite, and granular bainite (GB). The presence of a large amount of martensite/austenite (M/A) constituents within bainite results in a multitude of hydrogen trap sites. HIC cracks in bainite generally propagate along the profiles of M/A constituents, showing both intergranular and transgranular cracking modes.
Requirement Dependency Extraction Based on Improved Stacking Ensemble Machine Learning
Authors: Guan Hui , Xu Hang , Cai Lie
Published: April 2024

To address the cost and efficiency issues of manually analysing requirement dependency in requirements engineering, a requirement dependency extraction method based on part-of-speech features and an improved stacking ensemble learning model (P-Stacking) is proposed. Firstly, to overcome the problem of singularity in the feature extraction process, this paper integrates part-of-speech features, TF-IDF features, and Word2Vec features during the feature selection stage. The particle swarm optimization algorithm is used to allocate weights to part-of-speech tags, which enhances the significance of crucial information in requirement texts. Secondly, to overcome the performance limitations of standalone machine learning models, an improved stacking model is proposed. The Low Correlation Algorithm and Grid Search Algorithms are utilized in P-stacking to automatically select the optimal combination of the base models, which reduces manual intervention and improves prediction performance. The experimental results show that compared with the method based on TF-IDF features, the highest F1 scores of a standalone machine learning model in the three datasets were improved by 3.89%, 10.68%, and 21.4%, respectively, after integrating part-of-speech features and Word2Vec features. Compared with the method based on a standalone machine learning model, the improved stacking ensemble machine learning model improved F1 scores by 2.29%, 5.18%, and 7.47% in the testing and evaluation of three datasets, respectively.
What about the Use of Ice Cream as a Supplementary Diet in Chronic Kidney Disease? A Case–Control Study
Authors: Metro Daniela , Corallo Francesco , Cardile Davide , Gembillo Guido , Manasseri Luigi , Santoro Domenico , Buda Martina , Calabrò Rocco Salvatore , Bonanno Lilla
Published: April 2024

Maintaining a healthy lifestyle can extend life expectancy and improve a person’s health status. In addition to physical activity and bad habits related to smoking and alcohol, diet is also a determining factor. Following a healthy diet pattern over time and supporting a healthy body weight contributes to reducing the risk of developing more severe complications associated with very common diseases such as chronic kidney disease (CKD), diabetes, or cardiovascular diseases. The 2015–2020 Dietary Guidelines for Americans promote the adoption of fat-free or low-fat diets and discourage the consumption of foods with added sugar and solid fats, such as ice creams and other frozen desserts. On the other hand, ice cream, from a nutritional and healthy point of view, can be considered a possible food choice, due to its greater palatability and high nutritional content, but its consumption must be scheduled in a balanced diet. In this retrospective study, 36 patients with chronic renal failure were enrolled. Two different diets were proposed (A and B). In Diet B, lemon sorbet was added twice a week as an alternative food to replace fruit or snacks making the diet more varied and palatable. Nutritional status and biohumoral, immunological, and blood parameters were evaluated after 6 months. A statistical analysis shows a significant inter-group difference in creatinine and azotemia between T0 and T1. Intra-group significant differences were found in lymphocytes (p = 0.005) and azotemia (p < 0.001) in Diet A, and in azotemia (p < 0.001) and transferrin (p < 0.001) in Diet B. The results indicated that ice cream represented a good alternative food in both groups of patients regarding nutritional values and patient satisfaction. Furthermore, the treatment with ice cream allowed for better control of azotemia, maintaining stable levels even in patients with advanced CKD. This study concludes that ice cream could exert beneficial effects in addition to CKD patients’ dietary regimens.
Abietane-Type Diterpenoids from the Arils of Torreya grandis
Authors: Gao Yuqi , Yang Jinghui , Zhang Yue , Gao Linlin , Tian Junmian , Han Wenbo , Gao Jinming
Published: April 2024

A chemical investigation of the arils of Torreya grandis led to the isolation of seven abietane-type diterpenoids (compounds 1–7) including three previously undescribed compounds, one unreported natural product, and three known analogs. The structures of these compounds were determined by means of spectroscopy, single-crystal X-ray diffraction, and ECD spectra. An antibacterial activity assay showed that compounds 5 and 6 had significant inhibitory effects on methicillin-resistant Staphylococcus aureus, with MIC values of 100 μM. Moreover, compounds 1, 3, 4, and 7 exhibited anti-neuroinflammatory activity in LPS-stimulated BV-2 microglia cells, with the IC50 values ranging from 38.4 to 67.9 μM.
Terroir Dynamics: Impact of Vineyard and Canopy Treatment with Chitosan on Anthocyanins, Phenolics, and Volatile and Sensory Profiles of Pinot Noir Wines from South Tyrol
Authors: Tchouakeu Betnga Prudence Fleur , Poggesi Simone , Darnal Aakriti , Longo Edoardo , Rudari Elena , Boselli Emanuele
Published: April 2024

The effects of canopy treatment with chitosan and the effects of the vineyard location on the quality parameters, volatile and non-volatile profiles, and sensory profile of Pinot Noir wines from South Tyrol (Italy) were studied. Multivariate statistical analysis was applied to identify the most relevant compounds associated with the variability in phenolics and anthocyanins (analyzed by UHPLC-MS), volatile components (HS-SPME-GCxGC-ToF/MS), and basic enological parameters. A clear separation of low-altitude wines (350 m.a.s.l.), which had a high concentration of most of the identified volatile compounds, compared to high-altitude wines (800 and 1050–1150 m.a.s.l.) was pointed out. Low altitude minimized the concentration of the most significant anthocyanins in wines from a valley bottom, presumably due to reduced sun exposure. Wines obtained from chitosan-treated canopies, and, more particularly, those subjected to multiple treatments per year showed a higher amount of the main non-volatile phenolics and were sensorially described as having “unpleasant flavors” and “odors”, which might suggest that grape metabolism is slightly altered compared to untreated grapevines. Thus, optimization of the treatment with chitosan should be further investigated.
Skeletal Editing: Ring Insertion for Direct Access to Heterocycles
Authors: Li Xue , Xu Zhigang
Published: April 2024

Skeleton editing has rapidly advanced as a synthetic methodology in recent years, significantly streamlining the synthesis process and gaining widespread acceptance in drug synthesis and development. This field encompasses diverse ring reactions, many of which exhibit immense potential in skeleton editing, facilitating the generation of novel ring skeletons. Notably, reactions that involve the cleavage of two distinct rings followed by the reformation of new rings through ring insertion play a pivotal role in the construction of novel ring skeletons. This article aims to compile and systematize this category of reactions, emphasizing the two primary reaction types and offering a thorough exploration of their associated complexities and challenges. Our endeavor is to furnish readers with comprehensive reaction strategies, igniting research interest and injecting fresh impetus into the advancement of this domain.
Correction: Sarwer et al. Green Synthesis and Characterization of Silver Nanoparticles Using Myrsine africana Leaf Extract for Their Antibacterial, Antioxidant and Phytotoxic Activities. Molecules 2022, 27, 7612
Authors: Sarwer Qudsia , Amjad Muhammad Shoaib , Mehmood Ansar , Binish Zakia , Mustafa Ghazala , Farooq Atikah , Qaseem Mirza Faisal , Abasi Fozia , Lastra José Manuel Pérez de la
Published: April 2024

The authors wish to make the following corrections to this paper [...]
Effectiveness of Mentorship Using Cognitive Behavior Therapy to Reduce Burnout and Turnover among Nurses: Intervention Impact on Mentees
Authors: Ohue Takashi , Menta Masaru
Published: April 2024

Objective: Mentoring programs can improve nurses’ mental health. This study examined the effects of a staff training program based on cognitive behavior therapy for burnout in which mentors provided intervention to their mentees. Methods: The principal investigator served as a facilitator and conducted staff training in cognitive behavior therapy. An original cognitive behavior therapy manual was presented to trained nurses (mentors), and lectures were provided on using the manual, ways of implementing cognitive behavior therapy, and other important points. The study participants included 35 mid-career nurses (mentors) and 34 young nurses in their first to third year (mentees) working in acute care hospitals. Groups of five mentees were formed in which two mentors provided cognitive behavior therapy based on the manual. Changes in mentees’ stress, burnout, and turnover intention at pre-intervention, post-intervention, and follow-up (3 months after the intervention) were objectively evaluated using an evaluation index. Results: The intervention significantly reduced the following evaluation indicators: total strain, conflict with other nursing staff, nursing role conflict, qualitative workload, quantitative workload, conflict with patients, problem avoidance due to irrational beliefs, escape-avoidance, emotional exhaustion of burnout, desire to change hospitals or departments, and turnover intention. Conclusion: Implementation of cognitive behavior therapy by mentors effectively reduced mentees’ stress, burnout, and turnover.
Conservation of the Rare and Endangered Vascular Plants in the Mining and Tourism Area: Khibiny Mountains, Murmansk Region, Russia
Authors: Borovichev Eugene A. , Kozhin Mikhail N. , Koroleva Natalia E. , Petrova Olga V. , Akhmerova Diana R. , Shulina Maria V.
Published: April 2024

The Khibiny Mountains (hereafter called Khibiny Mts.) are one of the most urbanized and industrialized regions in the Russian Arctic. There are combined a developed mining complex, elaborate infrastructure, a well-known tourist resort, and a large population, all amidst an exceptionally rich biodiversity of plants. In this study, we analyzed the current knowledge of the spatial distribution of rare and endangered vascular plants and vegetation and the impacts of human activities on these ecosystems. Approximately 28% of the protected vascular plant species in the Murmansk Region were registered within the confines of the Khibiny Mts. In particular, although only a handful of protected species had a widespread presence, most rare species were confined to the southern reaches of the mountain range, with only a select few extending into other parts. Papaver lapponicum was the only species that thrived across the entire territory, including industrial areas. The studied territory contained nine specially protected areas spanning 123,220 hectares. Nature monuments adjacent to mining sites and urban centers play an important role in preserving regional biodiversity. However, the expansion of the mining industry, alongside deforestation and wildfires, poses considerable threats to the biodiversity of the Khibiny Mts. A comprehensive biodiversity conservation strategy implemented in this region balances the local and expansive territorial protection of rare species and habitats, ensuring environmental preservation while facilitating social and economic progress, a noteworthy example of environmental protection in the Arctic.
High Consistency Silicone Rubber Foams
Authors: Hofmann Timo , Giesen Ralf-Urs , Heim Hans-Peter
Published: April 2024

Silicone elastomers are high-performance plastics. In the extrusion process, only high-consistency silicone rubbers were used. In order to reduce the cost and weight, silicone rubbers can be foamed during processing. In this study, high-consistency silicone rubber is processed with different physical and chemical blowing agents. The resulting reaction kinetics, as well as the mechanical and morphological properties, had been investigated and compared with each other. This showed that the chemical blowing agent significantly influenced the crosslinking reaction compared to the microspheres and the water/silica mixture tested, but it also achieved the lowest density compared to the physical blowing agents. When evaluating the foam morphology, it became clear that the largest number of pores was achieved with the microspheres and the largest pores when using the water/silica mixture. Furthermore, it has been shown that the different mechanisms of action of the blowing agents have a major influence on the mechanical properties, such as the micro shore hardness and the foam morphology.
Sustainable Development Processes for Renewable Energy Technology II: An Overview
Authors: Zhironkin Sergey , Rybar Radim
Published: April 2024

This Special Issue, titled “Sustainable Development Processes for Renewable Energy Technology II: An Overview”, presents a collection of papers in the field of sustainable development in the mineral resource sector, detailing the “seamless” process of transforming energy production into the use of renewable sources [...]
Impact of Wellbore Cross-Sectional Elongation on the Hydraulic Fracturing Breakdown Pressure and Fracture Initiation Direction
Authors: Jolfaei Somaie , Lakirouhani Ali
Published: April 2024

Investigation of breakdown pressure in wellbores in complex conditions is of great importance, both in fracture design and in wellbore log interpretation for in situ stress estimation. In this research, using a two-dimensional numerical model, the breakdown pressure is determined in ellipsoidal and breakout wellbores. To find the breakdown pressure, the mixed criterion is used, in which the toughness and the tensile strength criteria must be satisfied concurrently. In breakout boreholes, the breakdown pressure is lower than the circular wellbores; indeed, the ratio of the breakdown pressure of the breakout wellbore to the breakdown pressure in the circular wellbore is between 1 and 0.04, depending on the deviatoric stress and the width and depth of the breakout zone. In breakout wellbores, the fracture initiation position depends on the deviatoric stress. In small deviatoric stresses, the fracture initiation position is aligned with the minimum in situ stress, unlike circular boreholes; and in large deviatoric stresses, the fracture initiates in the direction of the major principal stress. In large wellbores, the breakdown pressure is controlled by the tensile strength of the rock; and in small wellbores, the breakdown pressure is under the control of the energy spent to create new crack surfaces.