bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of the Difficult Economic Situation on the Operation of Slovak Companies in the Shadow of War
Authors: POÓR József , KOSÁR Silvia TÓBIÁS , HUSZÁRIK Erika Seres , ZSIGMOND Tibor , KÁLMÁN Botond Géza , TÓTH Zsuzsanna
Published: October 2024

Purpose: The purpose of this study is to examine the organizational and human resource (HR) responses to the challenging economic conditions caused by the war and the COVID-19 pandemic. Given the limited evidence available on how organizations adapt to such crises, this research aims to develop a conceptual model and empirically investigate the influence of two specific factors: organizational size and direct economic ties with the Russian and Ukrainian markets. Methodology: This study employs a mixed-method approach, combining both theoretical and empirical research. A conceptual model was first developed to outline potential organizational reactions to crisis conditions. The empirical part of the study involved data collection from 128 organizations, including companies and institutions, in Slovakia. The analysis was conducted to test two hypotheses regarding how organizational size and economic connections with the Russian and Ukrainian markets affect organizational and HR responses in times of war. Findings: The findings of the study indicate that neither organizational size nor direct economic linkages with the Russian and Ukrainian markets significantly influenced the responses of the organizations studied to the economic difficulties caused by the war. This suggests that other factors may play a more critical role in shaping organizational and HR strategies in response to crises. Implications for theory and practice: For theory, this study contributes to the existing literature by challenging the assumption that organizational size and direct economic ties to conflict-affected markets are primary determinants of organizational responses to crisis. For practice, the findings suggest that managers and HR professionals need to consider a broader range of factors beyond size and market exposure when developing strategies to cope with economic disruptions caused by global crises. Originality and value: This research is original in its focus on the specific impacts of war and pandemic-induced economic conditions on organizations in Slovakia. The study provides valuable insights into how organizations navigate crises, expanding the understanding of crisis management and organizational adaptability. It adds value by highlighting the need for more comprehensive models that consider a wider array of factors influencing organizational behavior in times of global economic disruption.
Análise da atuação da fisioterapia em pacientes com dispareunia pós câncer ginecológico: revisão integrativa
Authors: Débora Campos de Lima Débora Campos de Lima , Yasmin Podlasinski da Silva Yasmin , Pinto Farias Michele , Furlanetto Magda Patrícia
Published: October 2024

Introdução: A dispareunia é caracterizada pela dor antes, durante ou após a relação sexual. Pode ser classificada em primária ou secundária, superficial ou profunda e recorrente ou condicional. Esta disfunção é frequentemente encontrada após tratamentos oncológicos, gerando um impacto negativo na qualidade de vida, incluindo fatores físicos, psicológicos, sociais e sexuais. Objetivo: Revisar a literatura dos últimos 5 anos a fim de avaliar a atuação da fisioterapia no tratamento de dispareunia em pacientes que sofreram câncer ginecológico. Métodos: Trata-se de uma revisão integrativa de estudos que buscaram avaliar a atuação da fisioterapia em mulheres com dispareunia após câncer ginecológico, em artigos científicos publicados em revistas digitais entre os anos de 2017 a 2022, nas bases de dados PubMed, BVS, Science Direct, PEDro e SciELO. Resultados: Diferentes desfechos foram avaliados nesta revisão e mostraram uma melhora estatisticamente significativa na funcionalidade do assoalho pélvico, na função sexual, nos fatores psicossexuais, na qualidade de vida e também na possibilidade de manter os resultados após um ano de acompanhamento. Conclusão: Os estudos avaliados nesta revisão sugerem que a fisioterapia promove melhorias para mulheres com dispareunia após câncer ginecológico. Apesar de todas as pesquisas demonstrarem bons resultados, mais estudos são necessários para confirmar estes achados. Palavras-chave: Dispareunia; neoplasias dos genitais femininos; fisioterapia.
CONFLICTUALITE EN AFRIQUE DE GRANDS LACS : CAUSES, CONSEQUENCES ET PISTES PALLIATIVES
Authors:   Assistant à la Faculté des Sciences Sociales, Administratives et Politiques, Département des Relations Internationales de l’Université de Kolwezi/Lualaba-RDC, KAHILU Yannick KAZANGA
Published: October 2024

Cet article analyse les causes et les conséquences de la conflictualité dans la sous-région des Grands Lacs africains, ainsi que les conditions pour revenir à une paix durable dans cette sous-région. Il s’est agi des causes externes lointaines liées au partage et la colonisation de l’Afrique ainsi que des causes externes proches dues à la fin de la guerre froide, à la démocratisation et aux multinationales étrangères. Les conséquences de cette conflictualité sont notamment liées au rôle de la RDC, aux rivalités des puissances occidentales, à la criminalité et au trafic illégal d’armes, à l’exploitation illicite et au pillage des ressources naturelles. Enfin, la lutte pour l’hégémonie idéologique, ethnique et/ou nationale peut être réellement fondée sur le sentiment d’appartenir à la même communauté d’idées, le même peuple, la même nation, donc sur une identité collective. Mots-clés : Guerre, conflictualité, Afrique des Grands Lacs, paix.
CONFLICTUALITE EN AFRIQUE DE GRANDS LACS : CAUSES, CONSEQUENCES ET PISTES PALLIATIVES
Authors:   Assistant à la Faculté des Sciences Sociales, Administratives et Politiques, Département des Relations Internationales de l’Université de Kolwezi/Lualaba-RDC, KAHILU Yannick KAZANGA , TSHIJIK Jean-Luc TAMB ,   Assistant au Département des Relations Internationales de l’Université de Kolwezi/Lualaba-RDC
Published: October 2024

Cette analyse les attributs classiques de la puissance et relève les différentes ingérences dont certains Etats de la région des Grands Lacs Africains font objets, compromettant ainsi leur souveraineté et occasionnant une lutte pour le leadership régional. Il évalue ensuite, les facteurs de puissance de quelques pays en compétition du leadership dans cette région. Mots-clés : déchéance, souveraineté, puissance, interférence, politique, leadership.
Excavaciones en la muralla vaccea de Cauca
Authors: Blanco García Juan Francisco
Published: October 2024

Noticia de los primeros resultados obtenidos en las excavaciones realizadas en la muralla vaccea de Cauca.
NUEVOS DESAFÍOS EN MATERIA DE DIGITALIZACIÓN: DERECHOS FUNDAMENTALES, PROTECCIÓN DEL TRABAJADOR, SEGURIDAD Y SALUD EN EL TRABAJO
Authors: López Insua Belén del Mar
Published: October 2024

El crecimiento de la capacidad informática, la disponibilidad de datos y los avances en los algoritmos, han convertido la IA en una de las tecnologías más estratégicas del s. XXI. La IA ha dado lugar a la aparición de nuevas formas de desarrollo de la prestación laboral, fuera de los esquemas clásicos del contrato de trabajo. La gestión algorítmica implica el uso de técnicas de IA para planificar y gestionar los recursos humanos de una empresa. Ante ello, los juristas están obligados conceptualizar en clave jurídica el fenómeno, reconocer derechos y facultades donde corresponda, detectar posibles riesgos y peligros y, en consonancia, proponer requisitos, condiciones y límites al su uso de la IA, y este es el fin es el que pretenden conseguir los autores de esta obra. En la monografía se analiza de una forma minuciosa el Reglamento Europeo de IA desde la perspectiva de Derecho del Trabajo, y con diferentes vértices: evaluaciones de riesgo, selección de personal, sesgos y discriminación, prevención de riesgos laborales. Por otro lado, sobre las nuevas formas de trabajo, se estudian los empleos verdes, la regulación europea de plataformas digitales, la relación de las TICs con el derecho a la conciliación de la vida familiar y laboral. En definitiva, una obra de sumo interés para profesionales del Derecho, que puede ayudar a comprender la regulación actual, los derechos del trabajador, las obligaciones del empresario y las carencias normativas existentes.
HACIA UN MARCO EUROPEO DE ARMONIZACIÓN DEL TRABAJO EN PLATAFORMAS DIGITALES
Authors: Núñez-Cortés Contreras Pilar
Published: October 2024

El crecimiento de la capacidad informática, la disponibilidad de datos y los avances en los algoritmos, han convertido la IA en una de las tecnologías más estratégicas del s. XXI. La IA ha dado lugar a la aparición de nuevas formas de desarrollo de la prestación laboral, fuera de los esquemas clásicos del contrato de trabajo. La gestión algorítmica implica el uso de técnicas de IA para planificar y gestionar los recursos humanos de una empresa. Ante ello, los juristas están obligados conceptualizar en clave jurídica el fenómeno, reconocer derechos y facultades donde corresponda, detectar posibles riesgos y peligros y, en consonancia, proponer requisitos, condiciones y límites al su uso de la IA, y este es el fin es el que pretenden conseguir los autores de esta obra. En la monografía se analiza de una forma minuciosa el Reglamento Europeo de IA desde la perspectiva de Derecho del Trabajo, y con diferentes vértices: evaluaciones de riesgo, selección de personal, sesgos y discriminación, prevención de riesgos laborales. Por otro lado, sobre las nuevas formas de trabajo, se estudian los empleos verdes, la regulación europea de plataformas digitales, la relación de las TICs con el derecho a la conciliación de la vida familiar y laboral. En definitiva, una obra de sumo interés para profesionales del Derecho, que puede ayudar a comprender la regulación actual, los derechos del trabajador, las obligaciones del empresario y las carencias normativas existentes.
LA MODIFICACIÓN DE CONDICIONES DE TRABAJO POR CAUSA DIGITAL
Authors: San Martín Mazzucconi Carolina
Published: October 2024

El crecimiento de la capacidad informática, la disponibilidad de datos y los avances en los algoritmos, han convertido la IA en una de las tecnologías más estratégicas del s. XXI. La IA ha dado lugar a la aparición de nuevas formas de desarrollo de la prestación laboral, fuera de los esquemas clásicos del contrato de trabajo. La gestión algorítmica implica el uso de técnicas de IA para planificar y gestionar los recursos humanos de una empresa. Ante ello, los juristas están obligados conceptualizar en clave jurídica el fenómeno, reconocer derechos y facultades donde corresponda, detectar posibles riesgos y peligros y, en consonancia, proponer requisitos, condiciones y límites al su uso de la IA, y este es el fin es el que pretenden conseguir los autores de esta obra. En la monografía se analiza de una forma minuciosa el Reglamento Europeo de IA desde la perspectiva de Derecho del Trabajo, y con diferentes vértices: evaluaciones de riesgo, selección de personal, sesgos y discriminación, prevención de riesgos laborales. Por otro lado, sobre las nuevas formas de trabajo, se estudian los empleos verdes, la regulación europea de plataformas digitales, la relación de las TICs con el derecho a la conciliación de la vida familiar y laboral. En definitiva, una obra de sumo interés para profesionales del Derecho, que puede ayudar a comprender la regulación actual, los derechos del trabajador, las obligaciones del empresario y las carencias normativas existentes.
Characterization of Production Technologies Employed by Selected Small and Medium Scale Enterprises in Food Industry in Southwestern Nigeria
Authors:   The Polytechnic, Ibadan, Nigeria, Olagunju Y. , Oluwale Billy ,   African Institute for Science Policy and Innovation (AISPI), Obafemi Awolowo University, Ile-Ife, Nigeria, Ilori Matthew ,   African Institute for Science Policy and Innovation (AISPI), Obafemi Awolowo University, Ile-Ife, Nigeria
Published: October 2024

The study examined the production technologies used by selected small and medium enterprises (SMEs) in the food industry in Southwestern Nigeria. This is with a view to determining the extent to which production of quality foods is done with adopted technologies. The study was carried out in Lagos, Ogun and Oyo States in Southwestern Nigeria where there is high concentration of food processing firms (FPFs). Multi-stage sampling technique was used to select the local governments and towns with high concentration of FPFs in each state. Two hundred and fifty small and medium scale FPFs were selected using purposive sampling. Primary data were collected with two sets of questionnaire. The first set elicited information on the type and nature of production technologies and was administered on production managers of the firms. The second set elicited information on effectiveness of production technologies and was administered on one randomly selected production employee from each firm. Data collected were analyzed using mean and frequency distribution. The results showed that 48% of the production technologies of the firms were for baking, 31% were for filtration and 14.4% were used for pasteurization. Furthermore, 39.2% and 41.6% of the firms used automated and a mixture of automated and manual machines respectively. A total of 42% used imported machines, while 41.6% used a mixture of imported and local machines. Majority (74%) used batch production system. The study concluded that the reliance of firms on imported technologies, which they have poorly maintained, cannot help to achieve sustainable development in Nigeria.
A REALIZAÇÃO ABUSIVA DA FRENECTOMIA LINGUAL EM RECÉM-NASCIDOS, COMO TRATAMENTO DA ANQUILOGLOSSIA
Authors: Farias Ana Carolina Melo de Oliveira , Dias Francilena Maria Campos Santos
Published: October 2024

O presente trabalho aborda a realização abusiva da Frenectomia Lingual em recém-nascidos como tratamento para a Anquiloglossia, destacando os impactos que essa condição pode ter na vida do bebê. O objetivo é ressaltar a importância do diagnóstico precoce e do tratamento adequado, realizado por uma equipe multiprofissional, visando à saúde e ao bem-estar da criança e da mãe. O estudo investiga a banalização do procedimento, analisando as indicações e contraindicações da frenectomia, além de explorar os fatores que contribuem para essa prática, como experiências clínicas e a percepção dos pais sobre a anquiloglossia, ressaltando a preocupação com a realização indiscriminada da frenectomia, que, embora indicada em casos severos, tem sido frequentemente aplicada de forma desnecessária. O trabalho propõe a adoção de práticas baseadas em evidências e a educação dos pais como medidas essenciais para mitigar riscos e promover intervenções mais seguras. Recomenda-se o desenvolvimento de protocolos de avaliação padronizados, a formação de equipes multidisciplinares e o acompanhamento pós-operatório, sempre priorizando o bem-estar do recém-nascido.
NEUROPSICOLÓGICAS E PSICOLÓGICAS NO TRANSTORNO DO ESPECTRO AUTISTA ABORDAGEM IMPACTO TERAPÊUTICO
Authors: Arie Sarah Maya M.Mantler. T.
Published: October 2024

Este estudo aborda a importância das intervenções neuropsicológicas e  psicológicas no tratamento do Transtorno do Espectro Autista (TEA), enfatizando como essas práticas promovem o desenvolvimento das habilidades sociais e comunicativas dos indivíduos afetados. Utilizando uma abordagem multidisciplinar, são exploradas diversas técnicas, como a Análise do Comportamento Aplicada (ABA), a Terapia Cognitivo-Comportamental (TCC) e a Terapia Ocupacional. O estudo destaca a importância da personalização das intervenções e a participação ativa dos familiares, além de discutir os desafios enfrentados pelos profissionais que trabalham com autismo. Ao integrar diferentes abordagens terapêuticas, as intervenções psicológicas contribuem para a melhoria da qualidade de vida dos indivíduos com TEA e promovem uma maior inclusão social, escolar e familiar.
激光测风雷达在“9.9”天气过程的应用
Authors: 欧 紫娴 , 陈 求振
Published: October 2024

随着民航气象的不断发展，航空气象预报在航空安全中扮演越来越重要的角色，其中对低空风切变的预报一直是民航气象预报中的重点和难点，其特征在于尺度小、持续时间短，难以被常规设备监测，激光测风雷达由于其精密性，能有效对小尺度的风切变进行探测及告警，为了解风切变的成因机理以及激光测风雷达的使用效果，通过对2023-09-09三亚机场一次低空风切变过程进行详细分析，结果表明：激光测风雷达基本能清楚地探测到风切变的结构、位置、高度并相应提供告警；PPI4°仰角在此次过程能更加及时、清晰监测到低层风的辐合变化，此次过程中，将风廓线模式和下滑道模式进行综合应用，既可监测更高的高度，又可兼顾低层更加精细的下滑道风场变化，RHI探测模式相较前三者提前19min探测有低层风向的改变。雷达基本可以实现提前10min左右的预警；监测结果与机组报告结果有较好的一致性。
探索人工智能在空中交通管理的潜力与应用场景
Authors: 倪 昕超
Published: October 2024

为了分析人工智能在空中交通管理中应用的作用和价值，并展望其未来发展趋势。主要采用文献综述的方法，系统分析人工智能在空中交通管理中的应用现状、优势和局限。研究人工智能在空中交通管理中的应用，重点关注机器学习、自然语言处理、专家系统等技术在空中交通管理中的应用，并探讨其优势和局限。人工智能在空中交通管理中的应用，具有很大的潜力和价值。未来，随着人工智能技术的不断发展和应用，人工智能在空中交通管理中的应用将会越来越重要，为航空业界和学术界提供更多的机会。人工智能的研究和实践，能够进一步推动人工智能在空中交通管理中的应用和发展。
现代教育技术的发展及对教育的促进作用
Authors: 冯 雪燕
Published: October 2024

本文全面概述了现代教育技术的演进路径及其在教育领域中的推动作用。通过采用多媒体教学、虚拟现实、人工智能以及大数据分析等前沿科技，现代教育技术根本性地转变了传统的教学模式，显著提高了教学效率并优化了学生的学习体验。文章主要探讨了这些技术目前的应用现状，所面临的主要挑战及其未来发展的可能方向。
A Critical Analysis of Kurdistan Movement Leadership in Iran
Authors: Yusefi Keyhan
Published: October 2024

After the First World War, Kurdistan was further divided. In Iran, Reza Shah tried to assimilate the Kurds with his policies, but they fought back with uprisings such as that of Simko. The Kurdistan Democratic Party (KDP), founded in 1945, strove for self-determination and was able to form the Republic of Kurdistan for a short time before it was crushed in 1946. In the 1960s and 1970s, Kurdish politics were influenced by Marxism and political Islam.After the revolution in Iran in 1979, the Kurds strived for political participation but were suppressed. Ideological differences weakened the Kurdish liberation movement and led to a military defeat against the Islamic regime in Iran. Despite the setbacks, civilian activities and a renewed demand for self-determination continue, particularly via social media. The realisation of Kurdish self-determination requires unity across political and religious boundaries, with a collective, non-ideological approach at the forefront.
Machine learning based Computer Aided Tongue Diagnosis system for illness Prognosis
Authors: Patil Jaykumar M. , Kate Dipalee M. , Thakare Amita P. , Chaudhari Narendra , Gawande P. V.
Published: October 2024

Examining a patient's pulse, eyes, face, tongue, etc. has been a standard practice in medicine since ancient times. Because the tongue contains so much information, observing it is a hard task. The medical professional may learn something new by studying the Tongue's many regions, colours, and coatings. To diagnose internal organ problems by studying the tongue calls for a great deal of training and expertise. Disease prediction using tongue image analysis (DPTIA) was the central emphasis of the suggested model's artificial intelligence architecture. As a first step, the test picture undergoes pre-processing, various noise reduction processes, and colour improvements via the use of Fast Non-Local Mean (FNLM) filtering. To do this, the picture resolutions in the dataset are pre-processed. To further extract textural information, the Grey Level Cooccurrence Matrix (GLCM) is also used. The last step is to utilise the retrieved characteristics to identify the various illnesses using a Hybrid Extreme Learning Machine (HELM) classifier. A variety of diseases, including appendicitis, bronchitis, gastritis, heart disease, and pancreatitis, may be predicted using the DPTIA model. The proposed Computer Aided Tongue Diagnosis System (CATDS) model outperforms state-of-the-art methods like Random Forest and Support Vector Machine (SVM).
A Significant Correlation of Glutamine and Interlukin-6 with Pregnancy Rate in Women Undergoing ICSI
Authors: Hussein (D.O.G) Nidhal Abdulrazzaq , Al-Maliki (PhD) Rehab Shafiq Abdul Said , Jawad (PhD) Mufeeda Ali
Published: October 2024

Background: The composition of follicular fluid (FF) is significantly influenced by metabolic factors, and the analyses of metabolites in FF could reveal the correlation between metabolites and oocyte quality, embryo development, and pregnancy outcome. FF provides nutrients and growth factors that promote oocyte growth, development, and maturation.
Objective: To investigate the relationship between serum and FF glutamine and FF IL-6 levels and their influence on the pregnancy rate in women who are undergoing an ICSI treatment cycle.
Materials and Methods: A prospective cross-sectional study was performed on 90 women aged 20- 44 years who underwent ICSI treatment from July 2023 to February 2024. Serum and follicular fluid collected on the day of oocyte pick-up were used as biological material. The embryological laboratory examined the retrieved follicular fluid and collected oocytes using stereomicroscopy. ELISA analysed serum, FF glutamine and FF IL-6. The ICSI method was utilized for fertilization. The pregnancy test is done by measuring serum BHCG. Statistical data processing was conducted using the software package SPSS 23.
Results: There was a highly significant correlation between FF glutamine and FF IL-6 (p < 0.001)  and a positive correlation between FF glutamine and FF IL-6 with pregnancy rate ( p < 0.001) (p < 0.001 ).
Conclusion The correlation of FF glutamine and FF IL-6 affects the pregnancy rate in women undergoing ICSI. FF glutamine and FF IL-6 can be considered predictors for pregnancy while serum glutamine has no significance.
Differential Expression of Circulating miR-195 in a Sample of Iraqi Breast Cancer Patients Associations with Molecular Subtypes and Disease Stages
Authors: AbdulMuhsen Noor Esam , Aziz Ismail Hussein
Published: October 2024

Breast cancer (BC) is a multifaceted disease characterized by different molecular subtypes and stages. MicroRNAs (miRNAs)are increasingly becoming recognized as valuable tools for predicting and identifying persons with BC, particularly miR-195. This study aimed to evaluate the expression of miR-195 in BC patients and its correlation with demographic and clinical parameters. The study involved 60 female BC patients and 60 healthy controls. Demographic analysis showed that 65% of BC patients have a family history of BC. Invasive ductal carcinoma (IDC) was the most prevalent type (85%), and luminal A was the most common molecular subtype (57%). The majority of cases were in stage II (40%) and stage III (36%), with patients primarily in the 40-59 age range (70%). RT-qPCR analysis revealed significant upregulation of miR-195 (6.752 ± 4.06-fold change) in BC patients compared to healthy controls. However, expression levels varied among molecular subtypes and stages. Triple-negative BC patients showed significant downregulation of miR-195 (0.45±0.3-fold change) compared to other subtypes. Similarly, stage IV patients exhibited significant downregulation (0.63±0.24-fold decrease) compared to earlier stages. Interestingly, no significant differences in miR-195 expression were observed among different BC types (IDC, ILC, and others). These findings suggest that miR-195 could potentially serve as a biomarker for BC, particularly in distinguishing molecular subtypes and advanced stages. However, further research is needed to validate its clinical utility and understand its role in BC progression and prognosis.
Evaluation of Lifestyle for Women with Breast Cancer
Authors: Khalifa Mohammed F. , Hade Istikrar M. , Al_ Ghuraibawi Zahraa Adnan Ghadhban , Abid Ali Maryam Majid
Published: October 2024

Introduction: Breast cancer is a significant global health concern, affecting millions of women worldwide. While advancements in diagnosis and treatment have improved survival rates, the impact of this disease extends beyond physical health. It also significantly influences a woman's lifestyle and overall well-being. Objectives: The current study intends to analyze the lifestyle of breast cancer patients who are receiving therapy or are being followed up at the Oncology Teaching Hospital in Medical City, Baghdad, Iraq. Method: The present study uses a descriptive design with an application of an evaluation approach. A convenience sample of 100 women with breast cancer was selected from the Teaching Oncology Hospital at the Medical City in Baghdad City, Iraq. The study's objectives are served by a questionnaire. Physical, role, emotional, cognitive, and social functioning are its five functional domains. These domains are evaluated as low, moderate and high. Each study participant received a questionnaire explaining how to complete it, along with a form requesting their approval to remain anonymous. They also had the opportunity to leave the study at any time without being provided an explanation. A panel of (10) experts determines the questionnaire's content validity, and its internal consistency reliability is calculated via the split-half method with a Cronbach’s alpha correlation coefficient of (r=0.92). Data are collected using the study questionnaire, and they are then analyzed via a descriptive statistical data analysis approach on the basis of frequency and percentage. Results: The study revealed that the majority of these women experienced sleep issues, but most of them experienced problems with body weight gain (70%), social and community activity (70%), sexuality (60%), stress (60%), diet (56%), physical activity (50%) and smoking (45%), and some of them took birth control pills and used hormone replacement therapy (43%). Conclusion: This study revealed that women with breast cancer have experienced a variety of lifestyle domain-associated problems. These problems are clearly manifested in the results of this study.
Immunological Assessment of Interleukin-6 and 8 in Baghdad Patients with β-thalassemia
Authors: Aneed Nabaa Saeed , Fadhil Rusul Kareem , Kadhum Sarah Majid , Sadoon Nada Mohammed , Hussein Basim Jawad , Abood Ali Jalal
Published: October 2024

A genetic disorder known as β-thalassemia major is characterized by a decreased rate of hemoglobin synthesis, which results in inadequate binding of at least one globin chain. Depending on the exact illness, the actuality of deficiencies may vary. The study's model included participants who were not certain they had β-thalassemia, and a control group of fifty people who did not have the disease. The blood tests were assembled by the Medical city Thalassemia Center. between June 1st and October 31, 2023, to be exact. The purpose of this study was to evaluate the serum immunological marker levels, namely IL-6 and IL-8, in Iraqi patients suffering from β-thalassemia. The Panel has approved the survey design for the postgraduate examinations at the School of Baghdad. Human interleukin-6 (IL-6) and interleukin-8 (IL-8) unions were evaluated using the protein-associated immunosorbent assay (ELISA). The review's findings demonstrated that individuals diagnosed with β-thalassemia had notably elevated blood levels of IL-6 and IL-8, which is relevant information. IL-6 foci measuring 33.90±3.42 pg/ml were seen in β-thalassemia patients, whereas the reference group showed levels of 25.21±2.93 pg/ml. Comparably, the benchmark group's estimated IL-8 level was found to be 76.86±23.11 pg/ml, but the patient gathering revealed a higher IL-8 degree of 217.10±44.26 pg/ml. The results of this investigation demonstrate that individuals with thalassemia exhibit an insusceptible dysregulation characterized by concurrent inflammation and immunosuppression.
Kallistatin and Glypican-3 as Reliable Biomarkers for the Prediction of Liver Cirrhosis
Authors: Kasim Hayder Mohammed , Al-Fartosy Adnan Jassim Mohammed
Published: October 2024

Background: Cirrhosis is a condition in which the liver does not function properly due to long-term damage, this damage is characterized by the replacement of normal liver tissue by scar tissue. Objective: In the present study, an attempt was made to explore the role of kallistatin (KAL) and glypican3 (GPC3) as a predictor of liver cirrhosis (LC) in patients with hepatitis, non-alcoholic fatty acid and autoimmune diseases. Materials and Methods: This case–control study included 98 cirrhotic patients (34 patients with hepatitis B & A, 31 patients with non-alcoholic fatty liver disease and 33 patients with autoimmune) and 30 apparently healthy individuals. The laboratory investigations were performed, and the serum KAL and GPC3 were measured in all volunteers. Results: Serum levels of KAL, GPC3, and TAC were significantly decreased and MDA increased (p<0.01) in patients with LC as compared to control. The significant difference can also be indicatly seen in patients with hepatitis > non-alcoholic fatty acid > autoimmune diseases, respectively. The area under the curve (AUC) results obtained indicate that Kal and GPC3 could potentially be used as greater predictive biomarkers in LC with hepatitis ˃ NAFLD ˃ autoimmune diseases (Kal: AUC= -0.97, -0.91, -0.88; Gyp3: AUC=  0.89, 0.84, 0.79, respectively). Conclusion: Incorporating KAL and GPC3 screening into routine check-ups for patients with hepatitis, non-alcoholic fatty liver, and autoimmune diseases could aid in the early detection and prevention of LC-associated complications.
The Association Between Type 2 Diabetes Mellitus and Levels of Total Cholesterol, Low-Density Lipoprotein (LDL) Cholesterol, Very Low-Density Lipoprotein (VLDL) and the Role of Dehydrated Vegetables in Glycemic Control
Authors: Jaafar Hawar Jawdat , Jaafar Harez Jawdat , Jaafar Hawraz Jawdat
Published: October 2024

Objective: This study aimed to assess Total Cholesterol, Low-Density Lipoprotein (LDL) and Very Low-Density Lipoprotein (VLDL) Levels, identify specific lipid markers altered in individuals with type 2 diabetes mellitus (T2DM), and evaluate the correlation between HbA1C and total cholesterol, LDL cholesterol, and VLDL levels.
Materials and Methods: Ninety-six volunteers aged 35-72 with confirmed T2DM underwent total cholesterol, LDL, VLDL and HbA1c testing using the COBAS INTEGRA 400 PLUS device. Data on age, gender, diabetes status, and lipid profiles were collected in November 2023 to April 2024 from Layla Qasim Health Center located in Erbil, Iraq and then analyzed.
Results: Result: In our study, the prevalence of dyslipidemia among type 2 diabetes mellitus (T2DM) patients was 50.88%. This varied regionally, from 59.3% in China to 83.9% in Saudi Arabia. Dyslipidemia was more common in patients with poor blood glucose control. Weight and waist circumference were positively correlated with HbA1c levels, while age showed no significant effect on glycemic control. Women showed higher LDL and HbA1c levels than men. Although weak correlations were observed between HbA1c and LDL cholesterol, LDL was strongly correlated with total cholesterol and moderately with VLDL. Early detection and management of dyslipidemia is important to reduce the risk of cardiovascular disease in patients with T2DM.
Conclusion: Our study highlights the significant prevalence of dyslipidemia among patients with type 2 diabetes mellitus (T2DM), emphasizing the importance of lipid profile management to reduce the risk of cardiovascular disease. We found associations between weight, waist circumference and HbA1c levels, with gender differences in lipid profiles. While the association between HbA1c and LDL cholesterol was weak, early diagnosis and management of dyslipidemia could significantly reduce CVD risk, advocating a comprehensive strategy targeting both glycemic control and lipid management in T2DM patients.
Treatment of Full-Thickness Cutaneous Wounds Using a Novel Fish Skin Acellular Dermal Powder as Hydrogel with Gene Expression of Some Growth Factors Genes
Authors: Albayati Yasir S. , A. Q Alawadi , A. H. F. Al-Bayati
Published: October 2024

The purpose of this study is to evaluate how well fish skin acellular dermal powder hydrogel (FADPH)

promotes the healing of cutaneous wounds in Iraqi bucks. 48 of full-thickness cutaneous wounds (3X3 cm)

created on the dorsal back of twelve bucks, each two wounds on both sides. Then, divided into two groups

according  to  treatment  method (6  bucks  /group).  The  wounds  in  control  group  (A),  were  left  without

treatment and the wounds in treatment group (B) were treated by topical application of (FADPH). The

outcomes were assessed clinically, morphometrically scoring at (7, 14, 35, and 42) days post treatment, and

gene expression by RT-PCR of two genes including fibroblast growth factor (FGF) and epidermal growth

factor (EGF) at three times periods (0,7 and 14) days and histopathological assessment at (7,14, 35 and 42)

days post treatment. The scoring results of group B showed that the percentages of scoring results were

significantly higher than that of control wounds at the level of (P<0.001) from the first 7 days until the end of

the study. Also, results of gene expression of FGF and EGF was considerably higher in the treated group than

control  group  at  the  level  of  (p<0.001).  The  histopathological  results  in  group  B  showed  faster  re-

epithelialization of the epidermis, proliferation of fibrin and regenerated epithelia, dense collagen fibers, and

finally complete regeneration of the epidermal layer at the end of study in compared with group A which was

showed  slowly development  in wound healing proses  and highly inflammatory  reaction. In conclusion,

FADM hydrogel enhanced and accelerated the healing of skin wounds in male goats.
Análisis de los modelos de trasferencia tecnológica desde la diversidad de la información digital
Authors: Rodríguez Muñoz. Raúl
Published: October 2024

El artículo informa sobre el estado de los Modelos y sistemas de Transferencia de tecnología correspondiente a varios países latinoamericanos. Se utiliza el método analítico - sintético teniendo en cuenta el análisis de información cualitativa y la información cuantitativa se precisa referente al número de documentos específicos de acceso digital. El modelo latinoamericano de trasferencia de tecnología evidencia la necesidad de establecer los proyectos y las oficinas con la mencionada finalidad a lo cual se agrega una vigilancia de los resultados transferidos. Se confirmó la necesidad de que las Instituciones de Educación Superior cuenten con observatorios de vigilancia tecnológica para evaluar los cambios, tendencias y posibles trasformaciones en los Modelos y sistemas de transferencia de tecnologías. Apoyado en estos resultados se concluye, que es preciso para los países Latinoamericanos desarrollar ajustes en los nuevos modelos de transferencia de tecnologías, lo cual podría iniciarse por cambios en el sistema de relaciones entre los elementos claves la Universidad las oficinas de transferencia de tecnologías e innovar en estas relaciones entre la Universidad y empresa, al colocar las oficinas de transferencia de tecnologías como un ente articulador que asegure un proceso de retroalimentación y activación del sector productivo en los parques tecnológicos e incubadoras de empresas.
ESSAI DE TRAITEMENT BIOLOGIQUE DES HUILES LUBRIFIANTES USAGÉES RÉCUPÉRÉES DANS DES GARAGES DE KINSHASA À L’AIDE DES URINES HUMAINES ET KAOLIN EN RÉPUBLIQUE DÉMOCRATIQUE DU CONGO
Authors:   Faculty of Sciences and Technologies, Lanasa Alain , Ngangu Herve , N’siala Gurvitch , Mayimbi Samuel , Mbom George , Mbokadi Norbert , Kalulu Taba , Sungula Kayembe , Valu Gizanga , Makaly Biey
Published: October 2024

In the various car garages of Kinshasa (in the Democratic Republic of Congo), the lack of consideration of environmental standards is the basis of the voluntary and/or accidental discharges of used oils directly into the environment without any prior treatment. These used hydrocarbons are pollutants that can cause major environmental problems due to their toxicity. The aim of this study is to treat used lubricating oils from car garages biologically in order to reduce their toxic potential. To this end, an aerobic biological treatment system was set up by mixing 4L of used oils with IL of urine, 2Kg of active Kaolin and 20L of water. The reduction in the toxicity of hydrocarbons was assessed through acute toxicity tests on the species Gambusia Affinis and microbiological analyses before and after biological treatment of these oils. The results obtained on the toxicity before treatment of these oils revealed that the LC50 was around ±3 ml/g of used oils to say that the pollutant is very toxic. After biological treatment, the LC50 rise to around ±66.7 ml/g for the treated oils, which represents a significant reduction in toxicity and ranks these treated oils in the order of less toxic effluents. The microbiological analyses of the used oils before their treatment did not show any bacteria; on the other hand, the analyses after treatment made it possible to highlight the presence of bacterial colonies whose identification revealed the following bacteria: Citrobacter, Enterobacter, Klebsiella and Pseudomonas, which are mostly lipolytic. This study thus allowed to treat used oils thanks to microorganisms and the intrinsic properties of urine and Kaolin.
O atraso como condição da crítica
Authors: Zanola Gisele
Published: October 2024

In this article, we present Paulo Arantes' new interpretative approach to the manuscripts of The German Ideology: the understanding that the fundamental problem of Dialectic – the mediation between the universal and the particular, or, the settling of accounts between the idea and the effective reality – persists precisely in Marx and Engels’ consideration of the political and economic backwardness of Vormärz Germany and in the way in which post-Hegelian philosophy expresses this backwardness. By emphasizing Stirner’s critique of universals as fundamental to the Marx and Engels’ critique of ideology, Arantes both differs from the history of the classical reception of these manuscripts, which centralizes the authors’ critique of Feuerbach, and anticipates the widespread position in recent bibliography on Marx and Engels, without resorting, however, to philological studies, as has been done in the literature surrounding the MEGA² project since the 1990s. With this, the text that is commonly seen as a departure from philosophy towards the so-called historical materialism can be read as a “determinate negation [to idealism] [...] whose materialism, it can be seen immediately, does not stop at reducing ideas to the literal matter that supports them” (Arantes, 1996, p. 369).
The Necessary Illusion – Giannotti on Fetishism
Authors: Repa Luiz
Published: October 2024

The main aim of this article is to investigate the most fundamental meanings that José Arthur Giannotti attributes to the phenomenon of fetishism in Marx. His interpretation, as expounded in Certa herança marxista [Certain Marxist Heritage] and grounded in the concept of a necessary illusion in a predominantly Kantian sense, appears to challenge a fundamental aspect of the new readings that Uspian Philosophical Marxism, with Giannotti as a key figure, has advanced since the 1960s. These new readings have underscored the notion of real abstraction as the foundation of commodity fetishism in a predominantly Hegelian sense. The article aims to clarify that Giannotti's interpretation does not aim to replace one perspective with another but rather to integrate the initial insights of the critique of real abstraction with the illusory measurement practices inherent in the process of production and exchange of commodities.
First Pregnancy Abortion or Natural Pregnancy Loss: A Cohort Study of Mental Health Services Utilization
Authors: Studnicki James , Cox Tessa Longbons , Fisher John , Circucci Christina , Reardon David , Skop Ingrid , Craver Christopher , Tsulukidze Maka , Ras Zbigniew
Published: October 2024

Introduction: While both induced abortion and natural pregnancy loss have been associated with subsequent mental health problems, population-based studies directly comparing these two pregnancy outcomes are rare. We sought to compare mental health morbidity after an induced abortion or natural loss. Methods: Continuously eligible Medicaid beneficiaries age 16 in 1999 were assigned to two cohorts based upon the first pregnancy outcome: abortion (n = 1,331) or natural loss (n = 605). Outcomes were mental health outpatient visits, inpatient hospital admissions and hospital days of stay per patient per year. Average exposure periods before and after the first pregnancy outcome for each cohort were used to adjust the mental health service rates. Results: Prior to the first pregnancy outcome, all three utilization rates were significantly higher for the natural loss cohort compared to the abortion cohort. For the abortion cohort, the per-patient per-year increase from the pre- to post-pregnancy periods was significant for all three rates: 2.04 times for outpatient visits (p < 0.0001), 3.04 times for inpatient admissions (p = 0.0003), and 3.01 times for hospital days of stay (p = 0.0112). None of the pre-to-post rate increases were significant for the natural loss cohort. Conclusion: Higher pre-pregnancy use rates for women who experience a natural pregnancy loss indicate that increased mental health services use following abortion cannot be solely attributed to pre-existing mental illness. Only the abortion cohort, but not the natural loss cohort, experienced significant increases in mental health services use following the first pregnancy outcome. Keywords: abortion, miscarriage, mental health
Tumores a distancia y afectación orbitaria como manifestación inicial
Authors: Faretta Martina , Rodríguez Joaquín , Cardozo Laura , Rocco Camila , Valeiras Andrea
Published: October 2024

Objetivo: Revisar la frecuencia de aparición en corto plazo y las características de casos que tuvieron metástasis orbitaria de tumores primarios localizados a distancia.
Métodos: Se realizó un estudio retrospectivo de una serie de casos que incluyó pacientes que tuvieron metástasis orbitarias de tumores primarios localizados a distancia, atendidos entre enero y febrero de 2023 en un servicio de oftalmología. Se evaluaron las características como sexo, edad, localización del tumor primario, forma de presentación, métodos diagnósticos, tratamiento, evolución y supervivencia desde el diagnóstico.
Resultados: En el período de estudio se atendieron en el servicio de oftalmología 462 pacientes y se encontraron tres casos (0,6%) que cumplieron con los criterios de inclusión. La edad media al diagnóstico fue de 45,6 años (rango 29-6). En los 3 casos la metástasis fue unilateral. Las localizaciones del tumor primario fueron la mama, el pulmón y el testículo. Sólo 1 paciente tenía enfermedad neoplásica diagnosticada al momento de la consulta oftalmológica. Los signos y síntomas más frecuentes fueron  dolor, hiperemia bulbar, proptosis, ptosis, diplopía y disminución de agudeza visual. La supervivencia media fue de 3,8 meses desde el momento del diagnóstico. Los pacientes con cáncer de testículo y mama fallecieron en un corto plazo de tiempo desde el momento de la consulta.
Conclusiones: En dos meses se encontraron 3 casos de metástasis orbitarias de tumores de testículo, pulmón y mama, representando el 0,6% de los casos atendidos en nuestro servicio. En dos casos (66%) las manifestaciones orbitarias precedieron a la detección del tumor primario.
Trombofilia
Authors: Kovalivker Sol M. , Bonavita Constanza , Passarelli Florencia , Sarotto Lidia , Braccia Gancedo M. Laura
Published: October 2024

Objetivo: Reportar una forma de expresión de trombofilia a partir del caso clínico de una paciente con papiledema por trombosis de 2 senos venosos cerebrales producto de esa afección.
Caso clínico: Paciente femenina de 47 años de edad que concurrió al servicio de urgencias oftalmológicas refiriendo episodios de oscurecimientos transitorios de la visión, cefalea intensa y tinnitus. Al examen oftalmológico se evidenció edema de papila bilateral y en la angiorresonancia se detectó trombosis de senos venosos cerebrales. Luego de exhaustivos análisis clínicos y de laboratorio se confirmó el diagnóstico de trombofilia como responsable de la trombosis, por lo que se le realizó tratamiento anticoagulante con marcada mejoría de su cuadro clínico.
Conclusión: En este caso se resalta que la trombofilia puede ser causa de trombosis de senos venosos cerebrales, lo que puede generar en consecuencia papiledema bilateral.
Reabilitação estética de dente conóide: relato de caso
Authors: Santos Anna Danielle Oliveira dos , Melo Diana Fernandes de , Moya Jorge Alberto Carrazana , Sousa Kathleen Rebelo de , Souza Lizete Karla Filgueiras de , Linhares Marcela Lopes , Castelo Branco Márcio Langbeck , Linhares Márcio Lopes
Published: October 2024

As aesthetics advance in modern dentistry, people's expectations of their smiles become ever higher. Microdontia or conoid tooth, which refers to teeth smaller than normal, is one of the abnormalities that causes major aesthetic complaints due to its characteristics. Conoid teeth have a prevalence of 0.6 to 9.9%, with conical upper lateral teeth affecting approximately 55,000 people, with women being more susceptible than men. Many factors must be considered when restoring anterior teeth, depending on patient expectations and dental practice. The direct composite resin technique has stood out for providing aesthetic benefits, preserving tooth structure, being performed in a single consultation, being cheaper and not requiring any laboratory process. The objective of this study was to report a clinical case of aesthetic rehabilitation in a conoid tooth in the upper left lateral incisor with composite resin restoration using the direct technique. Clinical planning is essential for choosing the technique and restorative material to be used. Despite the various techniques proposed for the treatment of conoid lateral incisors, the aesthetic reanatomization with a direct veneer of composite resin, with diagnostic waxing, used in this study, was effective and inexpensive, allowing a minimally invasive treatment and possible posterior adjustments, enabling the restoration of self-esteem and the harmony of the patient's smile.
Harmonização estética do sorriso com lentes de contato dental: relato de caso
Authors: Nunes Aline Silva , Litaiff Guibson da Silva , Pereira Natália Stefany da Silva , Smith Camila Valente , Silva Jefter Haad Ruiz da , Melo Luciana Aleixo dos Santos de , Gonçalves Junior Fernando dos Santos , Ferreira Guilherme Motta Antunes
Published: October 2024

The harmonic smile has taken most patients to the dental office, which becomes a challenge for the Dental Surgeon. Among the various existing techniques for restoring anterior teeth, contact lenses are currently the most sought after. Thus, in this case, the objective was the report that addresses a rehabilitation through 20 ceramic laminates, in a 51-year-old patient, who sought care at the Faculty of Amazonas - IAES. The therapeutic option was discussed with the patient, aiming at the benefits of porcelain, and it was chosen. After previous procedures, the elements were prepared and adapted to receive the porcelain, where there was a minimally invasive preparation, respecting the patient's entire dental structure. This procedure generated better self-esteem and confidence when talking, smiling and eating, considering the cost-effectiveness of the chosen material.