bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalência do sofrimento emocional em profissionais de enfermagem no combate a Covid-19
Authors: De Araújo Ivani Iasmim , De Souza Talita Araujo , Alves Roberta Machado , Lucena Brunno Alves de , Bezerra Héllyda , Medeiros Arthur de Almeida , Barbosa Isabelle Ribeiro
Published: January 2024

Objetivo: Avaliar a prevalência do sofrimento emocional em profissionais de enfermagem que atuam no combate a COVID-19. Metodologia: Estudo transversal, web-based survey, realizado com profissionais de enfermagem de serviços de média e alta complexidade no Estado do Rio Grande do Norte, Brasil. Considerou-se como variáveis dependentes: prevalência de sentimento de incapacidade de controlar as preocupações e a prevalência de facilidade de ficar aborrecido ou irritado. As variáveis independentes foram características sociodemográficas e familiares, características do processo de trabalho e características de saúde mental. Para a análise dos desfechos realizou-se Regressão de Poisson. Resultados: A prevalência do sentimento de incapacidade de controlar as preocupações foi de 71,02% e de facilidade em ficar aborrecido e irritado foi de 75,31%. A análise multivariada demonstrou que o sentimento de incapacidade de controlar as preocupações esteve prevalente entre mulheres, da raça preta, com renda entre 3-4 salários mínimos, residentes em municípios com mais de 100 mil habitantes, possuem diagnóstico prévio de transtorno mental, apresentam sudorese, dificuldade de respirar, náuseas ou palpitações, reconhecem que a pandemia comprometeu as relações sociais, possuem sintomas de ansiedade e síndrome de Burnout. Conclusões: As consequências relacionadas à saúde mental podem persistir e gerar efeitos danosos mesmo em período pós-pandemia.
Fatores associados à saúde mental, sono e ocupação humana durante a pandemia do COVID-19 no Brasil
Authors: Mei Andre Eduardo , Chaves Ferretti Eliana , Stolses Bergamo Francisco Priscila Maria , Mei Paulo Afonso
Published: January 2024

O objetivo do estudo foi verificar associações entre ansiedade, depressão e alteração do sono com fatores ligados à rotina de trabalho, prática de atividade física e de lazer, participação social e Atividades Instrumentais da Vida Diária (AIVD).Estudo transversal com adultos (18 a 79 anos; n=2.695) que participaram da pesquisa Avaliação Online de Depressão, Ansiedade Generalizada e Transtornos do Sono durante a Pandemia de Coronavírus SARS-CoV-2 e responderam questionário eletrônico entre abril e maio de 2020. Com relação à saúde mental, 56,5% apresentaram episódios de ansiedade, 46,1% de depressão e 64,5% tiveram alterações do sono. Observaram-se associações estatisticamente significativas entre episódios de ansiedade e de depressão, e rotina de trabalho (p<0,05). Esses problemas, assim como alteração do sono, também estiveram associados ao tempo dedicado à atividade física e de lazer, de participação social e de realização de AIVD (p<0,05). Profissionais de saúde, principalmente terapeutas ocupacionais, podem contribuir em projetos terapêuticos e programas voltados para a saúde coletiva, auxiliando as pessoas a ampliarem seus repertórios ocupacionais e adaptarem sua vida ocupacional e cotidiana, em cenários como os vivenciados durante o período crítico da pandemia.
O impacto da pandemia na qualidade de vida dos jovens universitários de cooperação internacional: uma análise exploratória
Authors: De Sousa Nobre MATHEUS
Published: January 2024

Com o objetivo de avaliar o efeito da pandemia na qualidade de vida (QV) dos jovens universitários de cooperação internacional, foi realizada uma pesquisa observacional de delineamento transversal descritivo-exploratório com 169 alunos do ensino superior presencial da Universidade da Integração Internacional da Lusofonia Afro-Brasileira (UNILAB). A (QV) foi analisada utilizando o instrumento Medical Outcomes Study 36 itens (SF-36). Os resultados indicam que os estudantes brasileiros, especialmente o grupo feminino, apresentaram scores mais baixos para (QV) em comparação aos estrangeiros. Fatores como o consumo de bebida alcoólica, cigarro e reprovações em disciplinas influenciaram negativamente na QV desses jovens universitários. Por outro lado, o uso da religião e maior tempo livre foram fatores que proporcionaram melhores scores para (QV). Conclui-se que a pandemia teve um impacto significativo na qualidade de vida dos jovens universitários.
Democracia Participativa e a Democracia Representativa
Authors: Oliveira Santos Alethele , Delduque Maria Célia , Campos Alves Sandra Mara
Published: January 2024

RESUMO: o estudo teve como objetivo comparar o determinado no relatório final da VIII Conferência Nacional de Saúde e a produção legislativa federal posterior, com o intuito de saber se o Congresso Nacional observou as diretrizes da conferência. Metodologia: tratou-se de um estudo qualitativo em base de dados legislativos oficiais, em que se buscou documentos legais sobre o Direito à Saúde. O período levantado foi entre 1986 e 2016. Os textos normativos foram analisados pelo método de Análise de Conteúdo. Resultados: os achados demonstraram haver pelo menos cinco subcategorias relacionadas ao Direito à Saúde, leis produzidas em cada subcategoria. A produção legislativa sobre datas comemorativas foi a de maior número. Conclusão: O poder legiferante do Estado, durante as décadas estudadas não correspondeu às diretrizes do relatório final da VIII Conferência Nacional de Saúde.
Induction Shoots of Black Pomegranate (Punica granatum L.) Seed Explant Using Thidiazuron And Kinetin Hormone In Vitro
Authors: Popilia Intan , Linalatil F Khanna , Rohmah Mita Devi
Published: January 2024

Pomegranate is a fruit that has medicinal properties, it is proven by antibacterial, anti-inflammatory and anticancer activity. The aim of this study was to determine the best concentration of cytokinins in inducing shoots of black pomegranate seed explants (Punica granatum L.) in vitro. This study used one factorial, namely the addition of various concentrations of TDZ and kinetin. TDZ factor and kinetin with 6 treatment levels, namely 0 mg / L, 0.1 mg / L, 0.2 mg / L, 0.3 mg / L, 0.4 mg / L, and 0.5 mg / L, each treatment was repeated 4 times, for a total of 24 experimental units. The parameters observed included the day when the shoots appeared, the number of leaves, the length of the shoots and the day the leaves were fully open. Observation data were analyzed using Kruskal Wallis. The data showed that the cytokinin hormone, both kinetin and TDZ, was not able to significantly induce shoots on black pomegranate seed explants (Punica granatum L.). The hormone kinetin was able to induce shoots on explants of black pomegranate seeds (Punica granatum L.) with the best concentration of 0.4 ppm but the results were not significant. The optimal TDZ concentration in inducing callus appearance was 0.4 ppm with a callus appearance time of 24 DAP.
Schleichera oleosa (Molk.)Oken Callus Induced BAP and 2,4 D In vitro
Authors: Resmisari Ruri Siti , Rahmah Azizatur
Published: January 2024

Schleichera oleosa (Lour.) Oken is a plant that it can used as drug candidate. S. oleosa has several health benefits including as anti-cancer, anti-oxidant, and anti-microbial. One of technique for increasing the secondary metabolite in S. oleosa (Lour.) Oken is callus culture. This study is an experimental research using Factorial Completely Randomized Design (CRD). This study consist of 2 factors are  Benzyl Amino Purin (BAP) and 2,4-Dichlorophenoxyacetic Acid (2,4-D) with various concentrations. Based on the result of callus induction of S. oleosa (Lour.) Oken, it gives some different effect for the variable. The day of emerging callus and weight of callus give the optimum result at 2 mg/L 2,4-D + 0,5 mg/L BAP for 32 Day After Planting and 1,1458 grams. Besides, the percentage of callus formation at 1 mg/L 2,4-D + 0,5 mg/L BAP for 83,33%.
Supra-Cardiac Total Anomalous Pulmonary Venous Connection via Rare Right-Sided Vertical Vein
Authors: Mehnaz Atiq
Published: January 2024

A Total Anomalous Pulmonary Venous Connection (TAPVC) is an uncommon congenital anomaly which occurs as result of defective development or early atresia of common pulmonary vein. TAPVC is categorized into four with supracardiac variety occurring most frequently. Common pulmonary vein anomaly results in the retention of cardinal or umbilico-vitelline drainage systems. If cardinal venous system persists, it provides channels to the innominate or azygous vein, Superior Vena Cava (SVC). This case series reports two cases of supracardiac TAPVC draining into SVC via right-sided vertical vein. Careful evaluation before surgical repair is vital for such complex cardiac anomalies.
Analysis of the factors related to the early outcomes of Type B Acute Aortic Syndromes
Authors: Athayde Soares Rafael de
Published: January 2024

Objective: To determine the outcomes of endovascular treatment (ET) of Type B Acute Aortic Syndrome (AAS) and factors related to mortality and Spinal Cord ischemia. Methods: This was a retrospective cohort of complicated AAS patients who underwent endovascular treatment. The primary outcome variable was mortality rate and clinical outcomes. The secondary outcome variable was SCI. Results: Overall, 32 patients were evaluated, 10 patients submitted to CM and 22 patients ET. 100% of the patients had arterial hypertension, with a higher prevalence of male gender (53.1%). There was a higher prevalence of acute aortic dissection Stanford B with 19 cases (59.4%). Among the 22 patients submitted to interventional therapy, most of them thoracic endoprosthesis (TEVAR), with 16 patients (72.7%). A logistic regression showed that refractory chest pain (HR = 9,57; p = 0.005), aortic diameter higher than 40mm (HR = 16.65; p < 0.001), chronic renal failure (CRF) (HR = 5.2; p = 0.009) and SCI (HR = 1.89; p = 0.029) were related to increased mortality rate. Otherwise, male gender (MG) (HR = 17.20; p < 0.001), concomitant TEVAR + EVAR (HR = 3.88; p = 0.048), malperfusion (HR = 3.88; p = 0.038) and number of internal iliac patency (IIP) (HR = 6.52; p = 0.016) were associated to SCI. Conclusion: This study concluded that refractory chest pain, aortic diameter higher than 40mm, CRF and SCI were related to increased mortality rate. MG, concomitant TEVAR + EVAR, malperfusion and number of IIP were associated to SCI.
Autonomy Outcomes Measured with Barthel Index in Patients with Ischaemic Stroke during SARS-CoV-2 Pandemic. A Descriptive Study
Authors: Pego Pérez Emilio Rubén
Published: January 2024

Background: Acute stroke is the 3rd cause of mortality, the 1st in disability in the adult population, studies focused on the subacute stroke phase are less frequent, and those that focus on longer-term evolution are rare. Aim: To determine the functional repercussion in patients with ischemic stroke during the SARS-CoV-2 pandemic. Methods: A qualitative and retrospective study with a sample of 674 patients with acute ischaemic stroke that were selected. The outcomes were measured with Barthel index. Results: The distribution in the moderate and severe degrees has been higher for the year 2020, in the independent and mild degrees it has been higher in the years 2019 and 2021, for the degree of total dependence it has been higher in the years 2019 and 2021. No significant correlation was found between age and the result of the Barthel scale or between the year in which the stroke occurred and the result of the Barthel scale. Conclusion: No relationship is seen between the SARS-CoV-2 pandemic and worsening of functionality. The structural changes during the pandemic and the reduction in personnel have not affected the diagnosis and involvement of ischemic stroke. The effort of the staff, to maintain adequate care, has been decisive in the functional results of the patients.
Manajemen Pembelajaran Berbasis Hybrid Learning Pasca Pandemi di MTs Negeri 01 Kepahiang
Authors: Aziz Toher , Wanto Der , Kusen Kusen
Published: January 2024

Hybrid learning merupakan gabungan dari pembelajaran tatap muka dan pembelajaran online, Adapun beberapa Platform yang dianggap populer dalam kegiatan belajar ­Online seperti Zoom meeting, Google Classroom, Google Form, WA, Youtube, e-learning, Strategi pembelajaran dengan menggabungkan media offline dan online ini sering juga disebut sebagai metode pembelajaran Blended Learning ada juga yang mengistilahkan sebagai metode Hybrid Learning, pembelajaran hybrid yang telah digunakan oleh guru yang ada di MTsN 01 Kepahiang agar dapat berjalan dengan maksimal dan sesuai dengan apa yang diharapkan. Subjek penelitian ini adalah seluruh guru MTsN 01 Kepahiang sebanyak 40 Orang yang kemudian diklasifikasikan berdasarkan masalah penelitian yakni guru yang melaksanakan pembelajaran hybrid/blended 16 orang wali kelas, 2 orang guru yang menggunakan google classroom, 3 orang guru mata pelajaran matematika yang menggunakan aplikasi Alef,  40 orang guru mata pelajaran yang melaksanakan ujian, 3 orang menggunakan video youtube, Hasil penelitian bahwa berdasarkan hasil wawancara dan observasi dapat disimpulkan bahwa dalam proses dalam melaksanakan pembelajaran Hybrid pasca pandemi sudah dilakukan dengan baik dan menggunakan perangkat-perangkat maupun aplikasi-aplikasi yang tersedia yang dianggap paling mudah dan murah dalam penggunaannya dan dapat diaplikasikan secara menyeluruh oleh Guru dalam menyampaikan materi ataupun penugasan maupun peserta didik dalam menerima dan menyerap materi dan sebagai media komunikasi yang fleksibel dalam menghubungkan.
Manajemen Pendidikan Karakter Pada Sekolah Dasar Islam Kurikulum Terpadu (SDIKT) Robbi Rodhiya di Kota Bandar Lampung
Authors: Udhhiyah Lailatul , Kholid Idham , Yetri Yetri
Published: January 2024

Penelitian ini mengulas manajemen pendidikan karakter pada Sekolah Dasar Islam Kurikulum Terpadu (SDIKT) Robbi Rodhiya di Kota Bandar Lampung. Pendidikan karakter merupakan bagian penting dari proses pendidikan untuk membentuk generasi yang berakhlak mulia dan beretika. Penelitian ini bertujuan untuk mengevaluasi perencanaan, pengorganisasian, pelaksanaan, dan pengawasan pendidikan karakter di SDIKT Robbi Rodhiya. Metode penelitian yang digunakan adalah penelitian kualitatif dengan pengumpulan data melalui wawancara, observasi, dan analisis dokumen. Hasil penelitian menunjukkan bahwa manajemen pendidikan karakter di SDIKT Robbi Rodhiya mengutamakan peran guru dalam menanamkan nilai-nilai karakter kepada peserta didik. Proses pendidikan karakter melibatkan berbagai aspek, termasuk kurikulum, pelatihan, dan pembinaan. Perencanaan pendidikan karakter di sekolah ini telah diintegrasikan dengan baik dalam kurikulum, sedangkan organisasi pendidikan karakter melibatkan seluruh komponen sekolah. Pelaksanaan pendidikan karakter mencakup berbagai kegiatan seperti pramuka, pelajaran agama, dan olahraga. Pengawasan pendidikan karakter dilakukan melalui pemantauan oleh guru dan komunitas sekolah. Hasil penelitian ini dapat menjadi referensi bagi sekolah-sekolah lain dalam mengembangkan manajemen pendidikan karakter yang efektif dan berkelanjutan.
Analisis Pengembangan Karir Pegawai Pada Lembaga Pendidikan
Authors: Khairunnisa Khairunnisa , Wahyudin Achmad , Zohriah Anis
Published: January 2024

Pengembangan karir pegawai di lembaga pendidikan adalah hal krusial dalam memajukan kualitas pendidikan dalam era globalisasi dan perubahan konstan. Artikel ini membahas berbagai aspek pengembangan karir, termasuk pelatihan, pendidikan berkelanjutan, mentoring, evaluasi kinerja, kenaikan jabatan, kolaborasi, fasilitasi jaringan, serta pemberian reward dan pengakuan. Penelitian ini menggunakan metode kajian literatur untuk menganalisis kontribusi dan tantangan dalam pengembangan karir pegawai di lembaga pendidikan. Hasil penelitian menunjukkan bahwa pelatihan yang relevan dan disesuaikan, pendidikan berkelanjutan, serta pembinaan dan pemantauan yang efektif dapat memotivasi pegawai untuk meningkatkan kualitas pendidikan. Namun, diperlukan pendekatan yang bijaksana dalam kenaikan jabatan dan promosi, serta kolaborasi dan jaringan yang kuat untuk mendukung pengembangan karir yang holistik. Pemberian reward dan pengakuan juga dapat memotivasi staf, tetapi perlu dikelola dengan bijak. Dalam rangka menciptakan masa depan pendidikan yang lebih baik, lembaga pendidikan perlu mempertimbangkan strategi yang efektif dalam pengembangan karir pegawai mereka.
Efektivitas Komunikasi Intereprsonal Kepala Sekolah Dalam Perspektif The 5 Inevitable Laws of Effective Communication di MTs N 1 OKI
Authors: Astuti Mardiah , Marlina Leny , Fitriyanti Riska , Andini Dinda Rizki , Alam Muhammad Helmi
Published: January 2024

Penelitian ini bertujuan untuk mendeskripsikan tentang efektivitas komunikasi interpersonal kepala sekolah dalam perspektif “the 5 inevitable laws of effective communication” di MTs Negeri 1 Ogan Komering Ilir. Dalam penelitian ini menggunakan metode penelitian yang digunakan adalah metode kualitatif dengan pendekatan fenomenalogi. Adapun pengumpulan data dalam penelitian ini melalui teknik wawancara, observasi, dan studi dokumentasi. Sedangkan dalam teknik analisis data yang digunakan dalam penelitian ini adalah reduksi data, penyajian data, dan penarikan kesimpulan. Dalam hasil penelitian menunjukan bahwa pelaksanaan komunikasi interpersonal kepala sekolah di MTs Negeri 1 Ogan Komering Ilir sudah cukup efektif. Pengembangan komunikasi interpersonal yang efektif kepala sekolah ditinjau dari “the 5 inevitable laws of effective communication” yaitu implementasi dari respect, empathy (empati), audible, clarity, humble. Tentunya komunikasi interpersonal yang efektif juga harus di dukung oleh komunikator dan komunikan.
Konsep Sunnah Nabawiyah dalam Pendidikan Anak Usia Dini
Authors: Pramana Deky , Ismail Ismail
Published: January 2024

Penelitian ini bertujuan untuk memahami konsep pendidikan Nabi Muhammad dalam pendidikan anak sebagaimana yang telah beliau lakukan kepada sahabatnya yang berusia dini hingga dewasanya menjadi generasi terbaik bagi umat. Mengingat bahwa untuk menghadapi krisis pendidikan anak, diperlukan model pedagogis sebagai panduan dalam mengatasi tantangan tersebut. Bagi umat Islam, Nabi Muhammad dianggap sebagai uswatun hasanah atau teladan yang baik dalam kehidupan. Metode penelitian menggunakan pendekatan riset pustaka dengan analisis hermeneutik filosofis, mengumpulkan hadits Nabi dan menganalisisnya untuk membentuk pemahaman yang utuh tentang konsep Nabawiyah dalam pendidikan anak usia dini. Hasil penelitian menunjukkan bahwa pendekatan pendidikan Nabawiyah melibatkan berbagai model pembelajaran, termasuk pengajaran lisan, interaksi verbal, naratif, dan peragaan. Selain itu, pendekatan ini juga mencakup pemberian penghargaan dan sanksi sebagai bagian integral dari proses pendidikan.
İdrar Yolu Enfeksiyonlarında Ampirik Tedavi Tercihi Ne Olmalı?
Authors: ÖZDEMİR Metin , ŞENTÜRK KÖKSAL Zeynep
Published: January 2024

İdrar yolu enfeksiyonları hastane ve toplumda en sık karşılaşılan enfeksiyonların başında gelmektedir. Kültür imkanı olmayan durumlarda ampirik tedavi hastalığın sağaltım ve komplikasyonlarının önlenmesinde kritik öneme sahiptir. Bu çalışmada amaç kümülatif antibiyogram analizi ile klinisyene ampirik tedaviye başlamada yol gösterici olmaktır. 2014 Ocak - 2022 Aralık arasında laboratuvarımıza gelen idrar örneklerinin kültürleri yapıldı. Üreyen bakteriler konvansiyonel yöntemler, disk difüzyon, BD Phoenix (BD, ABD) ve Vitek2 (Biomerieux, Fransa) otomatize sistemleri ile identifiye edilerek antibiyotik duyarlılık testleri yapıldı. Bir hastada üretilen bakterilerin aynı türden olması durumunda ilk izolat verisi kullanıldı. Duyarlılık oranı %90 üzerinde olan antibiyotikler ampirik tedavide önerildi. Çalışmamızda idrar kültürlerinde üreyen etkenlerin %86,6’sının Gram (-) bakteriler ve toplamın %62,9’unun Escherichia coli olduğu görüldü. Tüm izolatlara bakıldığında ayaktan hastalarda siprofloksasin direncinin yüksek ve artmakta olduğu (%44,6); fosfomisin (%10,8) ve nitrofurantoin (%13,2) dirençlerinin düşük olduğu saptandı. Yatan hastalarda intravenöz olarak tercih edilen seftriakson direncinin (%63,3) yüksek olduğu, ertapenem direncinin (%29,3) daha düşük olduğu görüldü. Ayaktan ve yatan hastalarda üreyen E. coli izolatlarında nitrofurantoin ve ertapenem dirençlerinin %10 altında olduğu, E. coli dışındaki izolatlar için bu durumun geçerli olmadığı görüldü. E. coli izolatlarında tüm antibiyotiklere direnç oranının yatan hastalarda ayakta tedavi görenlere göre anlamlı yüksek olduğu saptandı (her biri için P
Telhado verde em edificações convencionais: estudo comparativo em um município do Sudoeste de Minas Gerais
Authors: Dalva Lima Lorena , Camargo Pedro Luiz , Silva Alves Felipe
Published: January 2024

Com o desenvolvimento das cidades, é possível ver a falta de área verde nos centros urbanos, por isso novas técnicas sustentáveis estão sendo aplicadas, como os telhados verdes. As coberturas sustentáveis possuem a mesma função das convencionais, porém mais do que isso, auxiliam no combate às ilhas de calor, na retenção de águas, diminuem a poluição sonora, entre outras vantagens. Neste trabalho, foram desenvolvidas planilhas que apresentam uma estimativa de custo real de implantação de cada tipo de telhado, sendo possível verificar qual deles é mais viável, listando suas vantagens e desvantagens. Devido a vários fatores, o valor de instalação do telhado verde é mais caro, porém deve-se levar em consideração as diversas vantagens que ele possui, tais como: auxílio ao combate às ilhas de calor, retenção de águas e diminuição da poluição sonora. Um dos motivos que torna o custo dessa técnica mais alto é a demanda, visto que, por ainda ser baixa, há poucas empresas especializadas no ramo, o que diminui a concorrência. Algumas cidades do Brasil já incluíram o uso dos telhados verdes nas leis municipais, porém seu uso ainda é pouco difundido. Portanto, políticas públicas e incentivos quanto à sua utilização devem ser desenvolvidos, buscando compatibilizar meio ambiente e crescimento urbano.
Role Clarity and Individual Performance at Work: The Role of Emotional Exhaustion and Interpersonal Justice
Authors:   IAGBT, f f , f f
Published: January 2024

Purpose - This study examines the effects of role clarity on individual performance at work and emotional exhaustion and the moderating effect of interpersonal justice on the relationship between them. Additionally, this study investigated the moderated mediating effect of emotional exhaustion on the relationship between role clarity and individual performance.
Design/Methodology/Approach - Data were collected through an online response method from 327 employees of companies located in Seoul, Korea. This study verified hypotheses using the SPSS 28.0 program and the PROCESS Macro v4.2 program.
Findings - The results of this study are as follows: first, role clarity was found to have a positive effect on individual performance and a negative effect on emotional exhaustion; second, interpersonal justice was shown to moderate the relationship between emotional exhaustion and individual performance; and finally, emotional exhaustion was found to have a moderated mediation of the relationship between role clarity and individual performance.
Research Implications - The results of this study have several practical implications. First, companies should clarify employees’ roles in performing their jobs through an accurate division of duties. Second, companies should attract and foster leaders who act fairly. Finally, companies should try to reduce the emotional exhaustion of their employees.
Calidad de las exportaciones manufactureras de México en el contexto de fragmentación internacional de la producción
Authors: Fujii-Gambero Gerardo , Morales-López Rodrigo
Published: January 2024

Hausmann, Rodrik y Klinger determinan la calidad de las exportaciones según el nivel de complejidad de las economías. El método se basa en la cercanía de los bienes producidos dentro de un país, la cual se establece por la estructura de la producción. Los productos que están simultáneamente presentes en la estructura productiva de un país son cercanos. Los productos se especifican según la Clasificación Uniforme del Comercio Internacional (CUCI) y, más recientemente, según el Sistema Armonizado. Argumentamos que, en el contexto de la creciente fragmentación internacional de la producción, la complejidad de las economías debe establecerse según su especialización por fases en los procesos productivos. Se estima la calidad de las exportaciones mexicanas de acuerdo con indicadores de composición de las exportaciones, origen del valor de las exportaciones, eslabonamientos hacia atrás de los sectores exportadores, tipos de bienes exportados y su uso por los importadores, propiedad del capital de las empresas exportadoras, investigación y desarrollo en los sectores exportadores y precios unitarios.
Enhancing the long-term cycling stability of Ni-rich cathodes via regulating the length/width ratio of primary particle
Authors: Han Duzhao , Zhang Jilu , Yang Mingyu , Xie Keyu , Peng Jiali , Dolotko Oleksandr , Huang Cheng , Wu Yuping , Shao Le , Hua Weibo , Tang Wei
Published: January 2024

Ni-rich layered oxide cathode materials are promising candidates for high-specific-energy battery systems owing to their high reversible capacity. However, their widespread application is still severely impeded by severe capacity loss upon long-term cycling. It has been proven that the cyclic stability of Ni-rich cathode materials is closely related to their microstructure and morphology. Despite this, the influence of the microstructure of primary particles on the fatigue mechanism of Ni-rich cathode materials during prolonged cycling has not been fully understood. Here, two Ni-rich layered spherical agglomerate oxides consisting of the primary particle with different length/width ratios are successfully synthesized. It is found that the long-term structural stability of both materials strongly depends on the microstructure of primary crystallites, although there is no significant difference between the electrochemical and crystalline characteristics during the initial cycle. A higher primary particle length/width ratio could effectively inhibit the accumulation of microcracks and chemical degradation during long-term cycling, thereby promoting the electrochemical performance of the cathode materials (80% capacity retention after 200 cycles at 1 C compared to the 55% of the counterpart with a lower primary particle length/width ratio). This study highlights the structure-activity relationship between the primary particle microstructure and fatigue mechanisms during long-term cycling, thereby advancing the development of Ni-rich cathode materials.
Light chain (AL) amyloidosis following gastrointestinal symptoms that involve multiple organs: a case report
Authors: Chen Yeqing , Wang Zhenxiang , Pi Xiaofang , Yuan Shuai , Tang Xueyu , Liao Yong , Wen Xing , Zhou Hongyu
Published: January 2024

Light chain (AL) amyloidosis is a complex and rare disease characterized by low incidence and diverse clinical manifestations. At the time of diagnosis, most patients exhibit involvement of multiple organs or tissues, leading to severe illness and a poor prognosis. Therefore, early diagnosis, active treatment, and a comprehensive assessment of the disease hold paramount importance. The initial presentation of this rare condition often manifests as gastrointestinal symptoms, posing challenges in clinical identification and differential diagnosis. In this case report, we describe a 70-year-old man with AL amyloidosis, initially misdiagnosed as irritable bowel syndrome and colon polyps. Subsequently, he experienced a series of complications including renal function impairment, pulmonary nodule, pleural effusion, mediastinal lymph node enlargement, spleen enlargement, reduction of white blood cells, red blood cells and platelets, and small intestinal obstruction. Despite multiple pulmonary nodule biopsy and lymph node biopsy, as well as concurrent splenectomy and partial resection of the small intestine, a clear diagnosis remained elusive. Before admission, diarrhea was aggravated, accompanied by emaciation and fatigue. Following the completion of serum immunofixed protein electrophoresis, renal biopsy, bone marrow and rectal biopsy, a conclusive diagnosis of AL amyloidosis involving multiple organs (Mayo 2012 revision stage III) was finally confirmed after a 12-year period. Treatment with proteasome inhibitors, immunomodulators, and glucocorticoids was recommended. The patient underwent methylprednisolone treatment and was discharged after symptom improvement. However, eight months into the follow-up, the patient succumbed to multiple organ failure. The repeated misdiagnoses over the past 12 years were attributed to limited perspectives among some specialists who did not conduct a systematic and detailed medical history analysis or comprehensive physical examinations. Additionally, they did not strictly follow the principle of "monism" in diagnosis. On the contrary, early diagnosis and active treatment of the disease are of great significance to improve the prognosis.
Study designs in medical research and their key characteristics
Authors: Nowak Dr Jan
Published: January 2024

Medical research study designs are many and varied. At first glance they may be difficult to distinguish. Knowledge of their specific strengths and limitations is useful for investigators planning new projects and for readers of the medical literature. This review has three aims: (i) to present an overview of medical research types, (ii) to attract attention to multiple characteristics of medical study designs, and (iii) to provide a concise educational resource for young researchers in health sciences. The goals are achieved by analyzing main characteristics of medical study designs.
Prognostic significance of grade of malignancy based on histopathological differentiation and Ki-67 in pancreatic ductal adenocarcinoma
Authors: Liang Yuexiang , Sheng Guannan , Guo Yu , Zou Yiping , Guo Hanhan , Li Zhifei , Chang Shaofei , Man Quan , Gao Song , Hao Jihui
Published: January 2024

Objective: Tumor cell malignancy is indicated by histopathological differentiation and cell proliferation. Ki-67, an indicator of cellular proliferation, has been used for tumor grading and classification in breast cancer and neuroendocrine tumors. However, its prognostic significance in pancreatic ductal adenocarcinoma (PDAC) remains uncertain. Methods: Patients who underwent radical pancreatectomy for PDAC were retrospectively enrolled, and relevant prognostic factors were examined. Grade of malignancy (GOM), a novel index based on histopathological differentiation and Ki-67, is proposed, and its clinical significance was evaluated. Results: The optimal threshold for Ki-67 was determined to be 30%. Patients with a Ki-67 expression level > 30% rather than ≤ 30% had significantly shorter 5-year overall survival (OS) and recurrence-free survival (RFS). In multivariate analysis, both histopathological differentiation and Ki-67 were identified as independent prognostic factors for OS and RFS. The GOM was used to independently stratify OS and RFS into 3 tiers, regardless of TNM stage and other established prognostic factors. The tumor-node-metastasis-GOM stage was used to stratify survival into 5 distinct tiers, and surpassed the predictive performance of TNM stage for OS and RFS. Conclusions: Ki-67 is a valuable prognostic indicator for PDAC. Inclusion of the GOM in the TNM staging system may potentially enhance prognostic accuracy for PDAC.
Time Evolution of Energy States
Authors: Oldani Richard
Published: January 2024

In order to describe the time evolution of energy states we choose to abandon the non-relativistic Hamiltonian method, which has been the standard for nearly a century, in favor of a more fundamental, relativistically correct Lagrangian method based on theories originally proposed by Dirac and Einstein. Integral equations of motion for the absorption and emission of radiation are derived that underlie and anticipate the differentially motivated Schrödinger equation. This new interpretation applies to a large volume of experimental evidence of both classical and quantum mechanical origin. Among the examples discussed in support are Planck’s law describing black body radiation, the function of the simplest quantum mechanical system an electron cyclotron, atomic clocks, matrix mechanics, chaos theory, and evolutionary biology.
A Machine Learning Approach to Understand the Impact of Temperature and Rainfall Change on Concrete Pavement Performance Based on LTPP Data
Authors: Argha Debo Brata Paul , Ahmed Md Ashik
Published: January 2024

Climate change is one of the most concerning global issues and has the potential to influence every aspect of human life. Like different components of society, it can impose significant adverse impacts on pavement infrastructure. Although several research efforts have focused on studying the effects of climate change on natural and built systems, its impact on pavement performance has not been studied extensively. Due to the weather effect the lifetime of pavement is getting lower on the other hand maintenance cost is getting higher and higher. The data has been collected from LTTP website and as a site The State of Texas has been considered. The primary objective of this project is to quantify the effect of temperature as well as precipitation changes on pavement response and performance prediction using the ARIMA model and develop a logistic regression model to analyze the forecast data.
Sarah’s גרש (Gāreš) and Abraham’s שלח (Šellach) of Hagar: Expulsion or Apostolic Mission?
Authors: Teke Metin
Published: January 2024

Abraham’s sending forth of Hagar and Ishmael in Gen 21:14 has generally been viewed as an expulsion. Popularly it is held that the primary, if not sole, purpose behind this act was to prevent Ishmael from interfering with Isaac’s inheritance. Interpreting, however, Sarah’s גרש (gāreš) demand and Abraham’s שלח (šellach) of Hagar through the lens of the narratives of Israel, Jesus, and Adam opens the passage to a new dynamic, one in which Hagar has been sent on a mission to establish a colony as an extension of their faith-based activity. An examination of the LXX and Josephus’ Antiquities of the Jews supports this view. Finally, an analysis of Abraham’s rule and motivations enables a mission objective behind Hagar and Ishmael’s being “sent forth” quite plausible. These approaches to the biblical story bring into focus a picture that is different from the standard interpretation where there are multiple objectives of Hagar and Ishmael’s being sent into the wilderness primary among them being expanding Abraham and Sarah’s evangelical mission.
Land Use and Cover Changes and the Occurrence of Dengue Fever in Minas Gerais State, Brazil: Governing Deforestation for Public Health
Authors: Andrade Ana Clara , Falcão Luiz Alberto Dolabela , Borges Magno Augusto Zazá , Leite Marcos Esdras , Santo Mário Marcos do Espírito
Published: January 2024

Several studies have already demonstrated the relationship between the loss of natural habitats and the incidence of diseases caused by vectors, such as dengue, which is an acute fever disease, considered a serious public health problem. The aim of the present study was to analyze the relationship between land use changes between 2009 and 2019 and the occurrence of dengue fever in 2015 and 2019 by municipality, using the state of Minas Gerais as a case study. For this, secondary data obtained from openly available sources were used. Natural vegetation cover data were obtained from the MAPBiomas platform and dengue occurrence data from the Ministry of Health, in addition to socioeconomic indicators from the Brazilian Institute for Geography and Statistics. Between 2015 and 2019, 1,255,731 cases of dengue were recorded throughout the state of Minas Gerais, ranging from 0 to 227 per thousand inhabitants between municipalities. The occurrence of dengue was distributed throughout all regions of Minas Gerais, affected by climatic and socioeconomic aspects. In general, municipalities with net loss of natural vegetation, predominantly located in the Cerrado biome, had the highest number of dengue cases in the studied period. Despite the significant positive relationship between these two variables, three of the eight socioeconomic parameters analyzed also affected the occurrence of dengue: population density, human development index (both positively) and Gini inequality index (negatively). These results indicate that, contrary to expectations, municipalities with better social conditions had more dengue cases. Our study indicates that natural vegetation is, directly or indirectly, involved in the ecosystem service of dengue control, despite the occurrence of this disease being affected by multiple factors that interact in a complex way. Thus, policies towards reducing deforestation must be complemented by a continuous investment in public health policies and reduction of social inequalities to efficiently control dengue fever.
Comparing the Zirconium Crowns’ Marginal Adaptation in Preparations with Two Different Occlusal Reduction
Authors: Khekan Ali , Kordaß Bernd
Published: January 2024

The aim of this study was to assess and contrast the effects on the vertical marginal fit of full contour CAD/CAM generated monolithic zirconia crowns pre- and post-cementation of employing chamfer finishing line designs with various occlusal reduction schemes (planar and flat) and cements. Material and Method: Forty sound human maxillary first premolars were selected for this study. Samples will be divided into two main groups of twenty samples in each group according to the occlusal reduction scheme: Group A: chamfer finishing line design with planar occlusal reduction scheme. Group B: chamfer finishing line design with flat occlusal reduction scheme. Each main group will be subsequently separated into two smaller groups based on the kind of cement that was utilized (n=10) Subgroup A1: crowns will be cemented by using resin-modified Glass Ionomer cement (Fuji Plus). Subgroup A2: crowns will be cemented using a Universal adhesive system (Duo Estecem II). Subgroup B1: crowns will be cemented by using Fuji Plus. Subgroup B2: crowns will be cemented using a Duo Estecem II. Result: Marginal gaps were measured at 4 indentations, using a Dino light-stereomicroscope (230X). Paired T-tests and student t-tests analyzed the data. Prior to cementation, subgroup A1 scored the lowest mean of vertical marginal gap values (80.284±23.021), while subgroup B2 scored the highest mean (118.597±9.956); following cementation, subgroup A1 scored the lowest mean of vertical marginal gap values (95.45±17.598), and subgroup B2 scored the highest mean of vertical marginal gap values (134.806 ±8.114). Chamfer finishing line design with a planar occlusal reduction scheme could be a preferable occlusal reduction scheme.
Study on the Separation and Mixing Characteristics of Wide-Grained Dense Medium in Vibration Separation Fluidized Bed
Authors: Fan Ruikang , Guo Zhibin , Guo Ziyi , Zhang Ronmiao , Wang Yifan , Xiong Sai
Published: January 2024

Vibro-fluidized dry coal beneficiation involves the unavoidable mixing of -1 mm coal dust into the fluidized bed, which compromises the stability and homogeneity of the bed density and reduces the effectiveness of fine-grained coal separation. In order to understand the features of coal powder separation and mixing (-1 mm) in a vibrating fluidized bed, as well as to achieve a uniform and stable bed density, a wide-grained dense medium consisting of -1 mm coal dust and 0.3-0.15 mm magnetite powder was homogeneously mixed in this work. The degree of density separation in the entire bed was examined, as well as the local mixing properties of the Wide-grained Dense Medium. It was discovered that when low vibrational energy was introduced at the same gas velocity, particle separation was enhanced in comparison to the usual fluidized bed. Little bubbles were found to ensnare fine coal dust and migrate upward, increasing density separation. The introduction of high vibrational energy leads to particle disorder within the bed and an increase in the level of particle mixing. The beneficial effects of vibration on the bed are diminished when the gas velocity is gradually increased under specified vibration circumstances. This causes big bubbles to develop more frequently, which increases particle mixing. Among them, the 1-0.5 mm fine-grained coal exhibits the best mixing state; it is less impacted by variations in air velocity and vibration levels, whereas the -0.5 mm coal dust is more affected by each of these variables. Furthermore, a wide range of air velocity regulation without a significant segregation state change was discovered to be achievable by the particle system under vibration circumstances of f=25Hz A=1mm and f=25Hz A=2mm.
Effects of Authentic Leadership on Intrapreneurial Intention: A Study in the Service Sector of Southern Spain
Authors: González-Cánovas Alejandro , Trillo Alejandra , Jiménez-Barrionuevo Maria Magdalena , Bretones Francisco D.
Published: January 2024

Nowadays, service sector workers face an increasingly demanding environment in terms of intrapreneurial behaviour due to the key role it plays in the survival of firms and the elimination of threats in the organisational environment. This paper investigates the antecedents of intrapreneurial behaviour in the service sector in southern Spain, analysing the interrelationships between authentic leadership, practised creativity, autonomy and meaningful work. This study employs a quantitative approach through the distribution of a questionnaire. A total of 333 employees in this sector responded to the research questionnaire. The results show that both meaningful work and creativity are direct antecedents of intrapreneurial behaviour. In contrast to these variables, authentic leadership was found to have significant negative effects on intrapreneurial behaviour, although it is essential for promoting employee creativity and autonomy and for fostering the perception of meaningful work. Finally, no significant relationship was found between autonomy and intrapreneurial behaviour. This research provides empirical results that can help broaden the understanding of intrapreneurial behaviour by highlighting the importance of balanced authentic leadership and offering guidance to organisations in designing a work climate that enhances organisational effectiveness.
Qualitative Properties of the Solutions to the Lane-Emden Equation in the Cylindrical Setup
Authors: Palestini Arsen , Recchi Simone
Published: January 2024

Some qualitative results are provided on the cylindrical version of the Lane-Emden equation. Although the explicit form of the solution is not exactly known, we establish some properties on the critical points of the solution in some specific cases and we propose a technique to evaluate the distance between a pair of solutions in small intervals.
Correlation of Presynaptic and Postsynaptic Proteins with Pathology in Alzheimer’s Disease
Authors: Serrano Geidy E. , Walker Jessica , Nelson Courtney , Glass Michael , Arce Richard , Intorcia Anthony , Cline Madison P. , Nabaty Natalie Lana , Acuña Amanda , Steed Ashton Huppert , Sue Lucia , Belden Christine , Choudhury Parichita , Reiman Eric , Atri Alireza , Beach Thomas G
Published: January 2024

Synaptic transmission is essential for nervous system function and the loss of synapses is a known major contributor to dementia. Alzheimer’s disease dementia (ADD) is characterized by synaptic loss in the mesial temporal lobe and cerebral neocortex, brain areas associated with memory and cognition. The association of synaptic loss and ADD was established in the late 1980s and it has been estimated that 30-50% of neocortical synaptic protein is lost in ADD, but there has not yet been a quantitative profiling of different synaptic proteins in different brain regions in ADD from the same individuals. Very recently, PET imaging of synapses is being developed, accelerating the focus on the role of synaptic loss in ADD and other conditions. In this study, we quantified densities of two synaptic proteins, the presynaptic protein SNAP25 and the postsynaptic protein PSD95 in human brain using enzyme-linked immunosorbent assays (ELISA). Protein was extracted from the cingulate, hippocampus, frontal, visual, and entorhinal cortex from cognitively unimpaired controls, subjects with mild cognitive impairment (MCI) and demented subjects with different levels of Alzheimer’s pathology. SNAP25 is significantly reduced in ADD when compared to controls in frontal cortex, visual cortex and cingulate; while hippocampus showed a smaller, non-significant reduction and entorhinal cortex concentrations were not different. In contrast, all brain areas showed lower PSD95 concentrations in ADD when compared to non-demented controls, although in hippocampus this failed to reach significance. Interestingly, cognitively unimpaired cases with high levels of AD pathology had higher levels of both synaptic proteins in all brain regions. SNAP25 and PSD95 concentrations significantly correlated with densities of neurofibrillary tangles, amyloid plaques and Mini Mental State Examination scores. Our results suggest that synaptic transmission is affected by ADD in multiple brain regions. Differences were less marked in entorhinal cortex and hippocampus, most likely due to a ceiling effect imposed by the very early development of neurofibrillary tangles in older people in these brain regions.
Improving Pediatric Patient Outcomes: An Interrupted Time Series (ITS) Approach to Explore the Impact of Rapid Response Teams in Reducing Unplanned PICU Admissions and Cardiopulmonary Arrests.
Authors: Al Harbi Samah
Published: January 2024

Background: Pediatric Rapid Response Teams (RRTs) are expected to significantly lower pediatric mortality in healthcare settings. This study evaluates RRTs' effectiveness in decreasing cardiac arrests and unexpected Pediatric Intensive Care Unit (PICU) admissions.

Methods: A quasi-experimental study (2014-2017) at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, involved 3,261 pediatric inpatients, split into pre-intervention (1,604) and post-intervention (1,657) groups. The intervention entailed pediatric specialists collaboratively managing acute decompensations following set protocols.

Results: RRT was activated 471 times, primarily for respiratory distress (29.30%), sepsis (22.30%), clinical anxiety (13.80%), and hematological abnormalities (6.7%). Family concerns triggered 0.1% of activations. Post-RRT implementation, unplanned PICU admissions significantly reduced (RR = 0.552, 95% CI 0.485-0.628, P < 0.0001), and non-ICU cardiac arrests were eliminated (RR = 0). Patient care improvement was notable, with a -9.61 coefficient for PICU admissions (95% CI: -12.65 to -6.57, P < 0.001) and a -1.641 coefficient for non-ICU cardiac arrests (95% CI: -2.22 to -1.06, P < 0.001). Sensitivity analysis showed mixed results for PICU admissions, while zero-inflation Poisson analysis confirmed a reduction in non-ICU arrests.

Conclusions: The deployment of pediatric RRTs is associated with fewer unexpected PICU admissions and non-ICU cardiopulmonary arrests, indicating improved PICU management. Further research using robust scientific methods is necessary to conclusively determine RRTs' clinical benefits.