bluuebunny/crossref_metadata_2025 huggingface dataset:
Toxicity study and effect of protein hydrolysates derived from black tilapia (Oreochromis placidus) on hypertensive induced mice
Authors: Kasran M. , Mohamed N. , Eshak Z.
Published: May 2024

Protein hydrolysates are specific protein fragments, produced during enzymatic hydrolysis and can exert various biological functions. The present study investigated the acute toxicity study of protein hydrolysates derived from black tilapia (Oreochromis placidus) and their effect on hypertensive-induced mice. Protein hydrolysates were produced from black tilapia protein isolate through enzymatic hydrolysis. A single dose of protein hydrolysates at 2000 mg/kg of body weight was administered and any changes were observed for 14 days. During 14 days, there were no significant changes in liver enzyme content and kidney function content, adverse clinical signs and mortality. The effect of the administration of protein hydrolysates in hypertensive-induced mice was studied. The body weight, blood pressure, full blood count {red blood cell (RBC), white blood cell (WBC) and platelets} were observed. Hypertensive mice (systolic blood pressure; 161±3 mm/Hg) were fed with pellet consisting of protein hydrolysates at different concentrations as well as carvedilol and combination of carvedilol and protein hydrolysates and systolic blood pressure was monitored. After 28 days, there was a significant reduction of blood pressure in the group of carvedilol (107±4 mm/Hg), 5% protein hydrolysate (119±1 mm/Hg), 10% protein hydrolysate (123±1 mm/Hg), 20% protein hydrolysate (115±2 mm/Hg) and 10% protein hydrolysate in combination with carvedilol (103±2 mm/Hg). Red blood cells significantly increased in hypertension mice but no significant changes in white blood cells and platelets after 28 days. Administration of protein hydrolysates reduced red blood cell levels similar to control group. A significant increase in body weight was observed in hypertension mice administered with protein hydrolysates at different concentrations as well as carvedilol and a combination of carvedilol and protein hydrolysates compared to control group and hypertensive group. Studies on any changes in liver enzyme level, kidney function level and angiotensin converting enzyme (ACE) activity on blood serum were carried out. Results showed that treatment with protein hydrolysates on hypertensive-induced mice reduced liver enzyme levels (ALP, ALT and GGT) and kidney function levels (Na+, K+ and Cl-) to normal levels. ACE enzyme activity of hypertensive-induced mice in the serum was also reduced similar to control mice after being treated with protein hydrolysates.
Disease risks arising from the disposal of fish‐ and horse‐derived by‐products
Authors: Seppä‐Lassila Leena , Joutsen Suvi , Järvelä Terhi , Rossow Heidi , Pasonen Petra , Tuominen Pirkko
Published: May 2024

Abstract
Animal by‐products are whole dead animals, parts of them and products obtained from them that are not used for human consumption. Legislation related to the utilization and disposal of animal by‐products was revised from the beginning of 2023, which limited the disposal of fish‐derived by‐products by burying or delivering them to a landfill in some parts of Finland. The aim of this risk assessment report is to describe the practices followed in remote and non‐remote areas and to assess the possible disease risk to humans and animals arising from the disposal of by‐products from fish and horse slaughtering as well as cutting plants. The risks related to using animal by‐products as carrion were also assessed.
At environmentally licensed aquaculture facilities, the delivery of by‐products to processing plant facilities was more common (67%) than at aquaculture facilities inspected based on risk (36%). The annual amounts of by‐products buried or delivered to the landfill were small in the non‐remote area, and slightly higher in the remote area. Horse‐derived by‐products were not produced in remote area slaughterhouses during the period under study.
Fish‐derived by‐products from approved food establishments were widely delivered for further processing, most commonly to produce fur animal feed. Disposal of fish‐derived by‐products by burying and delivering to a landfill or as carrion for wild animals was not common.
The dangers (pathogens) associated with the burial of fish‐ and horse‐derived by‐products for animals or humans were not considered significant. In carrion use, the spread of pathogens is more likely. The environmental effects of burying by‐products were not part of the mandate, but this should be studied in the future. Setting an annual upper limit for the by‐product to be buried is recommended. The specification of the remote area for fish could also be re‐evaluated.
Psychometric Properties of Update Arabic Version of the Trait Hope Scale and the Rosenberg Self-Esteem Scale
Authors: Ben Ayad Hatim , Kerekes Nóra , Sfendla Anis , Najdi Adil , Senhaji Meftaha
Published: May 2024

Hope and self-esteem are crucial components of positive psychology, and there is a lack of tools to assess these concepts in Morocco. Therefore, this study aims to provide the necessary instruments for evaluating hope and self-esteem among Moroccan college students. A total of 1150 college students (444 males, 703 females) completed an updated Arabic version of the Trait Hope Scale (THS) and the Rosenberg Self-Esteem Scale (RSES). The data underwent factorial and reliability analyses, with test-retest reliability assessed using responses from 26 students. Both the THS and RSES revealed a two-factor solution, and Multigroup Confirmatory Factor Analysis (MGCFA) demonstrated measurement invariance with respect to gender. Furthermore, the results indicated good and acceptable internal consistency (α = .85 for THS and α = .70 for RSES) and acceptable temporal stability (r = .72 for THS and r = .76 for RSES). In conclusion, the updated Arabic versions of the THS and RSES exhibited strong psychometric properties and stability. They have been established as valid and reliable tools for assessing hope and self-esteem among Moroccan college students.
Norway House Cree Nation reaping successes under Chief's leadership
Authors: Laskaris Sam
Published: May 2024

Story on Norway House Cree Nation under Chief Larson Anderson's leadership
Social value of renewable energy in remote northern Indigenous communities
Authors: Lim Anne Brigitte , Poelzer Greg , Noble Bram
Published: May 2024

Renewable energy (RE) is at the forefront of Canada’s strategy to achieve a net-zero electricity grid by 2035. The development of RE projects is also promoted as a means to deliver energy services in rural and remote Indigenous communities across the North. Although RE projects have the potential to contribute to sovereignty, self-sufficiency, and economic reconciliation, the social value of RE to Indigenous communities is often overlooked and poorly understood. This article advances themes for understanding and approaching RE developments to better assess their social value. It does so based on the analysis of lessons from RE research in northern Canada and Alaska. We demonstrate that RE projects can create outcomes that are value generating or value eroding and that such outcomes are often couched in the context of supporting or detracting from self-determination. Techno-human variables, from community vision and capacity to policy environments and local RE ownership, serve to enable or inhibit the realization of value-generating outcomes from RE. Finally, we identify several pathways to creation from RE, including relationships and collaborative leadership, knowledge and skills-development, Indigenous-led policies that decrease energy bureaucracy and manage benefits distribution, and regulations and structures that safeguard ecologies.
Phenomenology of Practice
Authors: Manen Max van
Published: May 2024

Phenomenology of practice is formative of sensitive practice, issuing from the pathic power of phenomenological reflections. Pathic knowing inheres in the sense and sensuality of our practical actions, in encounters with others and in the ways that our bodies are responsive to the things of our world and to the situations and relations in which we find ourselves. Phenomenology of practice is an ethical corrective of the technological and calculative modalities of contemporary life. It finds its source and impetus in practical phenomenologies of reading and writing that open up possibilities for creating formative relations between being and acting, self and other, interiorities and exteriorities, between who we are and how we act.
A new approach in the development of a dental caries vaccine
Authors: Rubnikovich S. P. , Poboinev V. V. , Khrustalev V. V.
Published: May 2024

The genomes of the bacteria Streptococcus mutans and Streptococcus sobrinus, which cause dental caries, currently have been fully sequenced. However, the secondary and tertiary structures of the full-size surface proteins of these microorganisms, by which they attach to the surface of teeth covered with saliva, have not been instrumentally determined at the moment. There are a number of experimental studies on the use of these proteins in the process of developing a dental caries vaccine. However, there is currently no commercially available dental caries vaccine.

The aim of the study was to choose an antigen for subsequent molecular modeling of a unique peptide for the development of a dental caries vaccine.

To develop an effective and safe dental caries vaccine, it is necessary to perform a number of experiments in silico, preceding experiments in vitro and in vivo. Today, this approach is not only generally recognized, but also allows to significantly reduce the cost of experiments and time at the preclinical and clinical studies. According to our hypothesis, as an antigen for the development of a dental caries vaccine, it is necessary to use a short fragment of the surface protein (a peptide) of Streptococcus mutans and/or Streptococcus sobrinus, whose homology in amino acid sequence is 84.8  %, the spatial structure of which should correspond to the spatial structure of the corresponding fragment in a full-sized protein. In addition, the selected protein fragment, which will be part of the vaccine peptide, must be available to antibodies, i. e. located on the surface of the protein and defined as a B-cell linear and spatial epitope. Also, according to our hypothesis, the vaccine peptide may consist of the most stable fragments of alanine and proline rich regions of the surface protein of Streptococcus mutans and/or Streptococcus sobrinus for mutual stabilization of the spatial structure.
Frequency of CYP2C19, P2RY12, ITGB3, ITGA2, and eNOS3 gene polymorphism in patients with myocardial infarction
Authors: Pronko Т. Р. , Snezhitskiy V. А. , Stsiapura Т. L. , Gorchakova О. V.
Published: May 2024

The aim of the study was to assess the distribution of polymorphic variants G681A (*2) of the CYP2C19 gene, H1/H2 of the P2RY12 gene, T1565C of the ITGB3 gene, C807T of the ITGA2 gene, and T786C of the eNOS3 gene in the population of the Grodno region, and to study their associations with myocardial infarction (MI). The study of the population consists of 493 people, including 400 patients with MI aged 31 to 74 years and 93 people of the control group aged 32 to 60 years. Research data (clinical and genotyping performed by polymerase chain reaction) were analyzed using STATISTICA 10.0 software. The prevalence of carriage of genotypes associated with high residual platelet reactivity and variability in response to dual antiplatelet therapy among patients with MI was 25.2 % for the G681A polymorphic locus of the CYP2C19 gene (GA + AA), and for the H1/H2 polymorphic locus of the P2RY12 gene (H1/H2 + H2/H2) – 40.0 %, for the C807T polymorphic locus of the ITGA2 gene (CT + TT) – 65.8, for the T1565C polymorphic locus of the ITGB3 gene (TC + CC) – 25.5, for the polymorphic locus T786C of the eNOS gene (TC + CC) – 69.2 %. Among the individuals of the control group, the frequency of occurrence of these genotypes was 18.3, 46.2, 60.2, 37.6, 48.4 %, respectively. In patients with MI, compared to the control group, the TT genotype of the eNOS gene was less common (χ2   =  13.6, p  =  0.0002), the CC genotype of the eNOS gene (χ2 = 5.4, p = 0.02) and the allele 786C of the eNOS gene (χ2 = 15.1, p = 0.0001) were more often detected. The carriage of the 786C allele of the eNOS gene increased the risk of MI in the studied population (OR = 2.0, 95 % CI: 1.41‒2.82, p = 0.0001). Gender differences were not found in the distribution of genotypes and alleles within the studied groups. There were no differences in carriage by the number of combinations of minor alleles between the control group and patients with MI. The most common combinations of minor alleles in both groups were comparable.
Mechanical properties of breast cancer cells of different molecular biological subtypes in reaction with antibodies against CD109 antigen
Authors: Shkliarava N. М. , Chelnokova I. А. , Nadyrov Е. А. , Krylov А. Yu. , Starodubtseva М. N.
Published: May 2024

The cytoskeleton is a participant in key cell events in oncogenesis and the reaction of cancer cells to therapeutic factors. The state and structure of the actin cytoskeleton contributes significantly to the mechanical behavior of cancer cells, forming the main features of their mechanical phenotype.

In the work, using atomic-force microscopy and fluorescent microscopy, we studied the changes in the structure of the actin cytoskeleton and parameters of the mechanical properties of breast cancer cells of different molecular biological subtypes (hormone-sensitive, line ZR-75, and triple-negative, BT-20 line, subtypes) when cells interact with the CD109 antigen, a TGF-β signaling pathway inhibitor. The use of antibodies for immobilizing the CD109 antigen has been shown to cause significant changes in the spatial organization of the actin cytoskeleton, stiffness and adhesive properties of the cell surface of both cell lines. Because of differences in the structure of the actin cytoskeleton, changes in the mechanical properties of the cells of different molecular biological breast cancer subtypes and the implementation of the TGF-β signaling pathway in these cells when binding to antibodies against the CD109 antigen occur in different ways. The obtained data open new perspectives for the development and evaluation of the effectiveness of anticancer drugs.
Pengembangan Ekonomi Kreatif Hasil Pertanian Dan Manajemen Bisnis Kecil Menengah Di Era Digital Di Desa Mekar Sari Sekotong
Authors: Bayu wijaya I gede , Suli Asmara Yanti Ni Nyoman , Sukendri Nengah , Kade Suparta Ida , Nyoman Sutrian Ida Ayu , Rani Putri Mahendri Ni Ketut
Published: May 2024

Perubahan orientasi ekonomi global ini, yang menekankan pentingnya aset sumber daya manusia, menghasilkan persaingan yang ketat dalam ranah kreativitas (kompetisi bakat global). Peningkatan kapasitas desa dapat meningkatkan kemandirian masyarakat pedesaan dengan mempromosikan potensi yang luar biasa, memperkuat institusi, dan memberdayakan masyarakat. Peningkatan daerah pedesaan melalui industrialisasi pertanian atau peningkatan produksi pangan bergantung pada kemajuan lokal dan ekspansi ekonomi. Terletak di dusun Nusa Sari, Desa Mekar Sari, dicirikan oleh ekonomi berbasis pertanian dan perkebunan, yang dapat menjadi sumber daya dalam membangun industri kreatif Usaha Mikro dan Kecil. Tujuan dari pengabdian kepada Masyarakat ini adalah memberikan pemahaman dan pelatihan tentang pemanfaatan sumber daya dari hasil pertanian dan perkebunan sehingga menjadi industry kreatif yang dapat dijalankan oleh Masyarakat pada lokasi pengabdian.
Metode yang digunakan pada pengabdian kepada Masyarakat yang pertama adalah dengan melakukan observasi sasaran yang dituju untuk diberikan pelatihan pengembangan industry kreatif.  Selanjutnya, sumber daya pelatihan yang diberikan kepada masyarakat, meliputi identifikasi prospek ekonomi dalam masyarakat, menanamkan dorongan kewirausahaan, dan mengawasi administrasi keuangan bergulir. Ini diikuti dengan eksplorasi semua aset yang layak dalam masyarakat yang dapat berfungsi sebagai dasar untuk kegiatan bisnis.
Hasil dari pengabdian kepada masyarakat menunjukkan bahwa dusun Nusa Sari, memiliki potensi yang besar untuk dimanfaatkan sebagai sumber daya yang dikelola oleh masyarakat yang menjanjikan untuk perdagangan dan memperoleh bahan-bahan yang diperlukan. Tingkat pendidikan para ibu dan remaja di Dusun Nusa Sari mempengaruhi kemampuan mereka untuk maju dan berkembang. Kurangnya modal ventura di antara mitra menghambat motivasi mereka untuk meningkatkan situasi ekonomi mereka. Meskipun demikian, mitra menunjukkan dedikasi yang kuat untuk secara efektif mengelola dana bergulir yang disediakan oleh tim proyek, yang bertujuan untuk mendukung modal kerja mereka
Pendampingan Penyusunan Rencana Usaha Sentra Industri Pengolahan Kelapa di Kabupaten Lombok Utara
Authors: Basuki Prayitno , Ismiwati Baiq , Dayani Rahman
Published: May 2024

Daerah Kabupaten Lombok Utara (KLU) memiliki potensi kelapa yang sangat besar di NTB, namun lebih banyak diperdagangkan dalam bentuk gelondongan ke luar Pulau Lombok. Akibatnya, KLU tidak banyak memperoleh nilai tambah dari perdagangan kelapa tersebut. Pada sisi lain, IKM pengolah kelapa KLU yang tersebar, berkelompok-kelompok, dan jumlahnya relatif banyak belum dapat beroperasi secara optimal, karena masih menjalankan praktik bisnis secara konvensional, sehingga belum banyak memanfaatkan potensi buah kelapa yang ada. Melihat seluruh kondisi tersebut Pemerintah KLU memfasilitasi berdirinya sentra industri pengolahan kelapa dengan maksud memanfaatkan potensi sumber daya lokal agar memberikan nilai tambah yang tinggi bagi IKM pengolah kelapa khususnya dan masyarakat serta pemerintah KLU umumnya. Tujuan kegiatan pendampingan kali ini adalah untuk memperkuat motivasi IKM pengolah kelapa yang tergabung dalam sentra industri pengolahan kelapa dalam menyusun rencana usaha yang akan mereka jadikan acuan selama 5 (lima) tahun ke depan
USE OF DIGITAL MEDIA AND TECHNOLOGY IN THE LEARNING PROCESS BY TEACHER SDIT BAITUSSALAM
Authors: Putra Lovandri Dwanda , Hedrina Lusy , Idam Devi Akita , Arifa Dian Nur
Published: May 2024

The world of education is currently increasingly developing. In the past, learning in schools usually used manual methods, namely teachers explained lessons in class by explaining directly to students . The aim of this research is to determine the use of digital media and technology at SDIT BAITUSSALAM. The research method used is descriptive qualitative. Media and technology in the world of education today is increasingly developing, one of which is at SDIT BAITUSSALAM. The school also has information technology-based facilities and infrastructure available . The technology at SDIT BAITUSSALAM uses computers. Learning media also plays an important role in the learning process to support smooth teaching and improve student learning outcomes . SDIT BAITUSSALAM utilizes learning media available in schools, for example maps, globes, atlases and photos of the Garuda Pancasila bird for classroom learning. Meanwhile, the technology used is LCD projectors and laptops. How to use it: Teachers usually use Kahoot and Quiziz for classroom learning . An interesting learning atmosphere at SDIT BAITUSSALAM, by using the Student Center Learning learning method teachers can invite students to be more active.
ARABIC-FUNDAMENTALS OF FINANCIAL INTEGRITY AND THEIR APPLICATIONS IN ISLAMIC LAW
Authors:   College of Education, Prince Sattam bin Abdulaziz University, Saudi Arabia, Mohammad Omar Abu Al-Majd Hussain Qasem
Published: May 2024

The study of the foundations of integrity and its applications in Islamic law stems from the priorities of reality, the requirements of safety of life, the development of society, and the success of economic and social life. This study came to show the foundations of integrity based on the legal evidence from the Holy Qur’an and the Noble Hadith, which included the method of trading public and private money and how to deal with job holders, and this is the first goal that the study sought to achieve, and revealed a number of provisions that preserve money and make disposal It is for the wise, and the hands of the foolish are restrained from it, and the basis of financial dealings is established on the basis of trust. For this reason, cheating, deceit, bribery, theft, and other things that mean encroaching on money are prohibited. As for the second objective represented in the legal applications, he studied a selected group of noble hadiths that give the reader an integrated picture of the comprehensiveness of these applications and their complete agreement with the provisions of the Noble Qur’an and the noble hadith, and at the same time make money a high value, preventing encroachment on it, whether it is little or a lot, and closes the outlets Deception and manipulation under the name of gift, favoritism, or others, noting that the meanings of the legal texts and their applications provide the basic foundation for fair financial action, far from extravagance, waste, or irresponsible behavior. The study concluded with some recommendations related to its subject.
URDU-AN ANALYTICAL STUDY OF THE SUBCONTINENTS’ SUFIS EFFORTS FOR ETHICS AND SOCIAL REFORMS
Authors:   Institute of Education and Research, University of the Punjab, Lahore, Salma Umme , Qayyum Aisha ,   Lecturer of islamic Studies Punjab college Minar e pakistan campus, Lahore
Published: May 2024

Sufism means purity and” Suf” is the name of purity of heart and action, which civilizes his conduct and affairs and becomes clean from the calamities of nature, and in reality, a Sufi is one whose heart is free from filth. Self-purification is a very important factor if a person wants to live peacefully and according to the wishes of Allah Almighty. Therefore, in every period of history. A large number of people were impressed by the simple teachings, lofty character, and fair treatment of the Sufis and entered the fold of Islam and contribution towards the spread of Islam in the sub-continent. The message of Islam was spread across the length and breadth of the sub-continent by the Islamic mystics. All work of educating people in the simple and direct message of Islam was done by Sufis like Ali Hajvery of Lahore, Khawaja Moinuddin of Ajmer, Khwaja Bakhtiyar Kaki, Baba Farid of Pakpattan, Sheikh Bahaudin Zakriya of Multan, Makhdoom Jahania Jhangasgt of Bahawalpur, Sheikh Nazimudin of Delhi etc. Sufis taught clear faith to the people around them. They did their best for inculcating the concept of the mercy of God in human hearts and eventually purifying spiritual and moral behaviors. The pleasures of honest dealing, sympathizing with fellow beings, and striving to obtain the nearness of God. Understanding the power of prayer and the beauties of faith, and ultimately fulfilling the duties and responsibilities.
Digital transformation in SMEs: Identifying cybersecurity risks and developing effective mitigation strategies
Authors: Lucky Bamidele Benjamin  , Ayodeji Enoch Adegbola  , Prisca Amajuoyi  , Mayokun Daniel Adegbola  , Kudirat Bukola Adeusi
Published: May 2024

This study delves into the cybersecurity landscape for small and medium-sized enterprises (SMEs), focusing on identifying prevalent cybersecurity risks, evaluating existing mitigation strategies, and exploring the role of innovation and technology in bolstering cyber resilience. Employing a systematic literature review and content analysis, the research scrutinizes academic journals, industry reports, and government publications from 2015 to 2024, to gather insights into the cybersecurity challenges and strategies pertinent to SMEs. Key findings reveal that SMEs are particularly vulnerable to a range of cyber threats, including phishing, malware, data breaches, and ransomware, primarily due to resource constraints, lack of awareness, and inadequate cybersecurity measures. Effective mitigation strategies highlighted include the adoption of comprehensive cybersecurity policies, regular employee training, and the implementation of advanced technological solutions. The study predicts an increasing reliance on artificial intelligence and machine learning for threat detection, alongside a growing trend of collaboration between SMEs and cybersecurity firms. The research underscores the necessity for supportive policies and frameworks that encourage SMEs to strengthen their cybersecurity posture, recommending financial incentives and the development of SME-specific cybersecurity standards. Building a cyber-secure culture within SMEs, characterized by organizational commitment and regular awareness programs, is identified as crucial for enhancing cyber resilience. Finally, the study emphasizes the importance of cybersecurity for SMEs, offering strategic recommendations for navigating digital threats and suggesting avenues for future research, including the exploration of behavioral aspects of cybersecurity and the impact of emerging technologies.
Agile methodologies: Adapting product management to rapidly changing market conditions
Authors: Prisca Amajuoyi  , Lucky Bamidele Benjamin  , Kudirat Bukola Adeusi
Published: May 2024

This review paper explores the effectiveness of agile methodologies in adapting product management practices to the dynamics of rapidly changing market conditions. The paper synthesizes existing literature on the application of agile principles across different sectors, focusing on how these methodologies facilitate responsiveness and adaptability in product management. The core analysis centers on the comparison of traditional and agile product management approaches, drawing on case studies and expert opinions to highlight the benefits and challenges associated with agile adoption. Key findings demonstrate that agile methodologies, such as Scrum and Kanban, enable organizations to enhance product innovation and customer satisfaction by fostering a culture of continuous improvement and rapid response to market feedback. Despite these advantages, the review also identifies potential drawbacks, including the complexity of transitioning to agile frameworks and the scalability of agile practices in large organizations. The paper argues that agile methodologies are crucial for companies aiming to remain competitive in fluctuating markets, provided there is a strategic commitment to agile transformation and an investment in overcoming the initial hurdles of adoption. Recommendations for effective implementation of agile practices in product management are provided to guide organizations in their agile journey.
Legal, regulatory, and policy framework hypothesis testing in a proposed e-procurement implementation assessment model framework
Authors: Md. Abdur Rashid  , Mohammad Shorif Uddin
Published: May 2024

Purpose: This paper investigated the essential variables that contribute to the successful implementation of an electronic procurement system in Bangladesh. Another goal was to build an efficient e-procurement implementation assessment model. Design/methodology/approach: The hypothesized model was operationalized with survey data from 206 samples of procurement entity (PE) officers collected via primary investigation. Survey questionnaires were employed to collect data from eleven zones in Roads and Highways Division (RHD) as a population in Bangladesh. Findings: The analysis found that the proposed conceptual framework for the e-procurement assessment model confidently asserts that the legal, regulatory, and policy framework was accepted. The results also demonstrated that the alternative hypothesis was accepted, so the proposed model was fit. Originality/value: The study was an early attempt for the first time to get the theoretical design of a unique e-procurement implementation assessment model that had been developed and proposed. The study's findings would be helpful to e-procurement practitioners. The suggested assessment model would further help review, implement, and modify subsequent e-GP policy/guidelines.
SOSIALISASI DIGITAL MARKETING UNTUK MENUNJANG PEREKONOMIAN YANG INOVATIF DAN KREATIF
Authors: Pradana Wildan , Sukaris Sukaris , Widiharti Widiharti , Rahim Andi Rahmad
Published: May 2024

Strategi dalam digital marketing dapat membantu pemasar untuk menganalisis kebutuhan konsumen dan membuat keputusan berdasarkan informasi yang diperoleh secara langsung dari konsumen. Seperti di daerah Gresik khususnya di kelurahan Kroman, banyak ditemukan potensi besar di wilayah tersebut namun warga menghadapi beberapa tantangan terutama dalam mengangkat produk lokal ke pasar yang lebih luas dengan seiring berkembangnya zaman. Sehingga permasalahan ini menjadi fokus dan tujuan bagi mahasiswa KKN, untuk menjadikan sebuah program kerja terkait pemasaran berbasis digital untuk mendukung pemasaran produk lokal dengan memanfaatkan teknologi khususnya di kalangan generasi muda. Pada saat pelaksanaan kegiatan, generasi muda di kelurahan Kroman mencapai 26% dimana mencapai seperempat populasi yang ada di kelurahan Kroman. Salah satu tantangan utama adalah komitmen yang berkelanjutan dari semua pihak baik. Selain itu terus beradaptasi terhadap perubahan teknologi yang dapat berevolusi dengan cepat. Berdasarkan temuan tersebut dapat disimpulkam bahwa program kerja sosialisasi digital marketing dapat meningkatkan kesadaran masyarakat kelurahan Kroman akan produk-produk lokal serta memperkuat partisipasi dalam ekonomi digital. Dengam terus memperkuat upaya dan melibatkan banyak pihak terkait, kami yakin daoat memperbaiki kualitas hidup masyarakan Kroman.
ANALISIS PERENCANAAN SISTEM PEMBANGKIT LISTRIK HYBRIDE (PLTS DAN DIESEL) PADA KAPAL TANKER
Authors: Akbar M Aidil , Tarigan Amani Darma , Lesmana Dicky
Published: May 2024

The hybrid power generation system (solar cells and diesel generator) is one of the alternative solutions to the negative impacts of conventional energy systems on ships in Indonesia. The use of this hybrid power generation system can support the development of environmentally friendly ship technology as global warming issues become more widespread. The advantages of implementing a hybrid power generation system include a reduction in fuel consumption by the generator and a simultaneous decrease in emissions from the ship. Choosing a hybrid system with solar power is particularly advantageous in Indonesia due to its abundant sunlight. This study employs technical and economic analytical methods to design a hybrid power generation system (solar cells and diesel generator). Technical and economic analyses are conducted using a tanker ship as the research object, comparing the hybrid power generation system with the conventional system widely used on ships in Indonesia. The research results indicate that the implementation of a hybrid power generation system on tanker ships results in a 15.5% annual fuel consumption saving compared to the use of conventional power generation systems. Therefore, due to the increased investment costs and reduced operational costs in the hybrid power generation system compared to the conventional system, the break-even point can be achieved in 3.69 years or equivalent to a total nominal cost of Rp 23,980,000,000.00 or $1,803,007.52.
Arsitektur Gereja yang Kontekstual
Authors: Hutagalung Fitry Hanna
Published: May 2024

Abstract. This paper studied the concept of contextual church architecture by focusing on the integration of theological, liturgical, and local cultural values, through case studies of the HKBP Parapat and HKBP Pondok Gede churches. The qualitative research methodology carried out involved a literature review and field research to investigate how church architecture can reflect and facilitate dialogue between Christianity and local culture, especially Toba Batak culture. The research finding emphasized the importance of incorporating local cultural elements and philosophies into church architecture to create worship spaces that are in harmony with their context and support the liturgical and socio-cultural needs of their communities.Abstrak. Tulisan ini mengkaji konsep arsitektur gereja kontekstual dengan memfokuskan pada integrasi nilai-nilai teologis, liturgis, dan budaya lokal, melalui studi kasus gereja HKBP Parapat dan HKBP Pondok Gede. Metodologi penelitian kualitatif yang dilakukan melibatkan tinjauan literatur dan penelitian lapangan untuk menyelidiki bagaimana arsitektur gereja dapat mencerminkan dan memfasilitasi dialog antara kekristenan dan budaya lokal, khususnya budaya Batak Toba. Temuan penelitian menekankan pentingnya memasukkan elemen dan filosofi budaya lokal ke dalam arsitektur gereja untuk menciptakan ruang ibadah yang selaras dengan konteksnya dan mendukung kebutuhan liturgi serta sosial-kultural komunitasnya.
“Tersungkurlah Ia Memohon pada Yesus”: Kritik Naratif Markus 5:21-24, 35-43 dalam Perspektif Tanggung Jawab Seorang Ayah
Authors: Raulina Raulina
Published: May 2024

Abstract. This study aimed to re-read the Gospel text Mark 5:21-24, 35-43 from the perspective of a father's responsibility. This perspective emerged from researchers' concerns regarding the widespread phenomenon of fatherlessness in families. The method used in this research is the narrative criticism method. The research result showed that the narrative of Jairus' struggle to find healing for his daughter can be a reflection of a father's responsibility. From the result of this re-reading, it can be concluded that reading a text using a different approach and perspective can produce new meanings that are relevant to contextual needs.Abstrak. Kajian ini bertujuan untuk melakukan pembacaan ulang teks Injil Markus 5:21-24, 35-43 melalui perspektif tanggung jawab seorang ayah. Perspektif ini lahir dari keprihatinan peneliti atas maraknya fenomena fatherless dalam keluarga. Metode yang digunakan dalam penelitian ini adalah metode kritik naratif. Hasil penelitian menunjukkan bahwa narasi perjuangan Yairus untuk mengupayakan kesembuhan bagi anak perempuannya dapat menjadi refleksi atas tanggung jawab seorang ayah. Dari hasil pembacaan ulang tersebut dapat disimpulkan bahwa pembacaan terhadap suatu teks dengan menggunakan pendekatan dan perspektif yang berbeda dapat menghasilkan makna baru yang relevan dengan kebutuhan kontekstual.
Vapaasti tuotettu puhe tutkimuksen kohteena
Authors: Toivola Minnaleena , Heikkola Leena Maria , Lintunen Pekka
Published: May 2024

Freely produced speech is a common source of data for speech research. This article is an introduction to this thematic volume and discusses freely produced speech from different perspectives. Freely produced speech is often seen as the opposite of controlled, often phonetic experiments in laboratory conditions. However, it is very difficult to determine which data collection methods are sufficient for freely produced speech to be considered authentic and natural. The topics of the articles included vary from dialectological research in Finland and the phonetic features of Namibian English to second language fluency studies as well as proficiency or speaker assessments in a second language. As this thematic issue will show, it is essential to conduct research on freely produced speech in a comprehensive way, as well as to understand the importance of the results obtained. The way freely produced speech is assessed can have a significant impact on an individual’s life, for example, in gatekeeper evaluations.
AUTHENTIC VIDEO
IN TEACHING UKRAINIAN AS A FOREIGN LANGUAGE
Authors: Lynchak Inna
Published: May 2024

In the article, the author analyses the scientific achievements of Ukrainian linguodidactics in the field of theoretical and practical comprehension of working with authentic audiovisual materials as an additional teaching source in the study of foreign language.
Numerous publications by Ukrainian scholars on this topic (from the early 2000s to the present day) are divided into 3 groups. The first group of articles focuses on the general issues of using the audiovisual method in the process of developing foreign language communicative competence. The second group of studies includes articles reviewing the most frequent “audiovisual practices” in the course of UFL. The third group of articles is in-depth research on working with certain genres of authentic video for foreign audiences.
The range of genres of authentic video products that can be used for educational purposes in the process of mastering UFL is outlined. These include feature films, documentaries, animated films, informative and entertaining TV programmes (news release, video interviews, academic lectures, video presentations, virtual tours of museums and cities of Ukraine, video blogs, TV shows, stand-up comedy, etc.), video messages from public figures, advertising blocks, trailers, music videos, etc. It is emphasized that among the above, Ukrainian methodologists pay the most attention to films of various genres (primarily short films). The article highlights the key issues that Ukrainian film didactics is working on. The article analyses the scientific studies of Ukrainian methodologists on the use of other genres of authentic video for linguodidactic purposes – video interviews, song videos, commercials, virtual tours, professional videos, etc. The author presents her own comments on the stated topic and outlines issues for the future. It is emphasised that working with authentic video requires the teacher to understand the specific purpose of its use in the classroom, knowledge of the repertoire of Ukrainian authentic material and its linguistic and didactic potential, and special methodological study for presentation in a foreign language audience.
Key words: authentic video, genre, listening, Ukrainian as a foreign language, linguodidactics.
Kajian Keamanan Sistem Informasi Akademik Menggunakan Framework COBIT 5
Authors: Supit Yonal , Edy Irwansyah
Published: May 2024

This study examines the security of academic information systems using the COBIT 5 Framework. Key issues are uncertainty in protecting student and staff data, the potential for cyberattack vulnerabilities, and non-compliance with international security standards. The goal is to evaluate the security level of the system and suggest improvement recommendations according to COBIT 5 principles. Research methods include Renstar IT policy analysis, system audits, and interviews with IT personnel and related academic communities. Data is analyzed quantitatively to identify weaknesses and opportunities for improvement. The COBIT 5 framework is used as a security assessment framework. The results highlight the need for improvement, including access management, activity monitoring, and continuous improvement plans. Using COBIT 5, substantial measures such as strengthening access controls and developing disaster recovery plans can be identified. The research emphasizes the importance of a structured approach in improving the security of academic information systems, with COBIT 5 as a useful tool. With the right measures, system security can be enhanced to protect the integrity, confidentiality, and availability of critical data for educational institutions. In conclusion, these measures demonstrate how important COBIT 5 implementation is in addressing information security challenges in academic environments.
Histodiagnosis of heterakidosis in chickens
Authors: Stafford V. V.
Published: May 2024

The purpose of the research is to study pathology findings in heterakidosis in broilers.

Materials and methods. The study used pathological material (cecum, liver) from 8 laying hens aged one year. Organ samples were delivered to the Pathology Sector in 10% buffered formalin. They were fixed for 36 hours and examined histologically using paraffin embedding. Semi-automatic Thermo Scientific equipment was used to process tissue samples. Histologic specimens were stained with hematoxylin and eosin. The specimen histoarchitecture was assessed with an Axio A1.0 microscope; photographs were taken using the AxioVision software.

Results and discussion. Visual assessment of the pathological material revealed thickening of the distal cecum while the liver samples had no signs of pathology. It was found that Heterakis spp. was about 1 cm long; helminth eggs were oval-shaped and had a strong, uniform shell; their size was 49 × 26 micrometers in the mean. When dwelling in the cecum, Heterakis spp. causes atony of the distal cecum wall, and development of inflammatory and necrotic processes in the intestinal mucosa, which promotes active growth of bacterial flora, accumulation of bacterial byproducts and intoxication. In places where the helminth is localized, eggs accumulate and a risk of Histomonas spp. infection increases, namely, amoebic (in the intestinal lumen) and spherical (in the intestinal mucosa) forms of the protozoan were identified. It was not possible to differentiate Histomonas spp. in assessing the histological specimens of the liver from the infected birds. In diagnostics, we should consider the great similarity of morphological characteristics of Heterakis spp. and Ascaridia spp. eggs.
The efficacy of antiparasitic drug based on Lufenuron, Moxidectin, and Praziquantel against ixodidosis in dogs
Authors: Tsepilova I. I. , Shemyakova S. A. , Bolatchiev K. Kh.
Published: May 2024

The purpose of the research is to study the efficacy of antiparasitic drug based on Lufenuron, Moxidectin, Praziquantel against ixodidosis in dogs under natural conditions and during experimental infection with ixodid ticks.

Materials and methods. The experiments used the drug in tablet formulation containing Lufenuron in 320 mg, Moxidectin in 9.6 mg and Praziquantel in 160 mg. To study the preventive and therapeutic acaricidal effect of the drug against ixodid ticks in the country part of the Karachaevsky District of the Karachay-Cherkess Republic, two groups (10 dogs each) were formed of Alabai dogs or outbred dogs with a body weight of 16–76 kg. The dogs of the first experimental group were administered the drug in tablets. The dogs of the second group served as controls and were not treated. The experiment used clinically healthy dogs of both sexes over 6 weeks of age, spontaneously infected with Ixodidae. Animals were selected so that they were not exposed to drugs for at least 1 month prior to the experiment. The animals were kept under normal conditions throughout the experiment and received their usual food. Antiparasitic tablets were administered to the dogs individually, once, orally, mixed with food at a dose of 1 tablet per 16–32 kg of body weight. The ixodid infection was diagnosed in the dogs by clinical examination. The genus of Ixodidae was determined by typical morphological characteristics. The drug efficacy was evaluated based on reduced number or absence of ticks on the treated animals (experimental) versus the untreated animals (control). Before the experiment and after the drug, the animals were examined every hour for 48 hours, and condition, separation, separation time from the start of the drug and death of the ticks were recorded; the dogs were then examined every 5–7 days for two months.

Results and discussion. The article presents study data on antiparasitic drug efficacy against ixodidosis in dogs spontaneously infected with Ixodes ricinus, I. persulcatus, and Dermacentor reticulatus. The result of the studies found that the antiparasitic drug (active substances were Lufenuron, Moxidectin, and Praziquantel) had a therapeutic effect that was recorded on day 5 after treatment and was 90%. The preventive efficacy was also above 70%: on day 7 and 14, this value was 90.0 and 86.9%, respectively, which indicated the duration of the preventive effect for 25–28 days. To fully evaluate the acaricidal efficacy against ixodidosis, studies were conducted on experimentally infected animals. Forty percent efficacy was determined at 48 hours after the drug; at 2 weeks after the drug, 90 %, 98.5 and 100 % efficacy were determined against ixodidosis in the dogs at 24 hours, 48 and 72 hours after the transfer of ticks, respectively. At 4 weeks after the drug, 100 % efficacy was determined against ixodidosis in the dogs at 24, 48 and 72 hours after the transfer of ticks, respectively.
VISUAL SIGNS ON THE BILLBOARD OF BALI ARTS FESTIVAL XLV YEAR 2023 : PEIRCE SEMIOTICS ANALYSIS
Authors: Gede Bayu Segara Putra  , I Kadek Jayendra Dwi Putra
Published: May 2024

This study is aimed at examining the visual signs found on the billboard of the Bali Arts Festival XLV Year 2023 using Charles Sander Peirce's semiotics approach. In an effort to understand how messages are communicated to the audience, an analysis is conducted on the icons, indexes, and symbols that appear in the design of the billboard. Through qualitative descriptive methods, the visual elements in the billboard are separated and observed, then analyzed using Peirce's semiotics framework. The results of the analysis indicate that the theme "Segara Kerthi" (Ocean of Harmony) is successfully represented in the billboard by using icons such as the illustration of Gajah Mina, which symbolizes the protector of the sanctity of the sea, indexes such as the rising sun, which depicts hope and a new beginning, and symbols such as government logos and social media icons that reflect support and technological advancement. These visual signs provide profound meanings related to the protection and appreciation of the sea as a source of life and civilization. In conclusion, this analysis provides a deeper understanding of how the visual signs in this billboard create a strong cultural identity, educate, and capture the audience's attention. This research offers a positive contribution to the analysis of visual communication works and has the potential to be further developed with diverse theoretical approaches and disciplines.
Educational cooperation between Indonesia and Russia as a tool of “soft power”
Authors: Sibarani Dame Maria Nova
Published: May 2024

Currently, Indonesia and Russia are interested in improving the image of the states among the most active part of civil society, as well as creating a more favorable investment and political climate for strengthening bilateral cooperation. The purpose of the article is to identify the mechanisms and features of educational cooperation between Indonesia and Russia. The author emphasized the branching structure of bilateral cooperation in this segment of Indonesian-Russian relations. The article assesses the effectiveness of the educational policy of Indonesia and Russia on the formation of an image component in the partner country, and also offers recommendations on strengthening the “soft power potential” of the two sides.
The Scent of Mating Strategy: Sociosexual Orientation Might Influence Body Odor Sniffing Behavior Through Subjective Importance of Olfaction in Chinese and American Populations
Authors: Chen Ying , Lv Huan , Wu Mengze , Mahmut Mehmet Kibris , Zou Laiquan
Published: May 2024

Human sexuality and mating behaviors have been linked to the subjective importance of olfaction and body odor in one’s life; however, the relationship among these factors has not been fully explored. Therefore, this study aimed to investigate the relationships between sociosexual orientation, subjective importance of olfaction, and body odor sniffing behavior, and to determine whether there is cultural consistency. A total of 1,904 Chinese college students (Study 1) and additional 861 participants from more general population (410 Chinese and 451 Americans) (Study 2) completed three questionnaires measuring sociosexual orientation, subjective importance of olfaction, and body odor sniffing behavior, respectively. The results of Study 1 indicated a significant association between sociosexual orientation, subjective importance of olfaction, and body odor sniffing behavior for both males and females. Besides, the subjective importance of olfaction mediated the relationship between sociosexual orientation and body odor sniffing behavior. The results of Study 2 suggested that the relationships between sociosexual orientation, subjective importance of olfaction, and body odor sniffing behavior were consistent across cultures. To conclude, this research highlights the significant association between sociosexual orientation, subjective importance of olfaction, and body odor sniffing behavior, which exhibited consistency across genders and cultural backgrounds. These findings provide valuable insights into the role of human mating strategies in olfaction.