bluuebunny/crossref_metadata_2025 huggingface dataset:
Main epidemiological data on cases of malignant neoplasms of the bladder in Saint Petersburg in 2012–2021
Authors: Popov S. V. , Guseynov R. G. , Khizha V. V. , Yazenok A. V. , Sivak K. V. , Pomeshkin E. V. , Perepelitsa V. V. , Bunenkov N. S. , Lelyavina T. A.
Published: August 2023

Background. Bladder cancer is the most common malignancy of the urinary tract and one of the most common neoplasias in this group. The incidence and mortality rates of the population from bladder cancer differ significantly in different geographical regions of Russia.Aim. To assess the main epidemiological indicators of malignant neoplasms of the bladder in residents of Saint Petersburg and the regions of Russia.Materials and methods. The main epidemiological indicators of malignant bladder neoplasms in Saint Petersburg, Russia and individual federal districts for the period 2012–2021 were studied: crude and standardized rates of morbidity, mortality, prevalence, age structure of patients, the number of cases of diagnosis of the disease at various stages, indicators of one-year mortality and 5-year survival, data on completed cases of treatment of bladder neoplasms. Sources of information: Form No. 7 “Information on cases of malignant diseases” and the database of the Medical Information and Analytical Center (Saint Petersburg).Results. During the period 2012–2021 in Russia, there was an increase in the incidence and prevalence of malignant neoplasms of the bladder. At the same time, mortality rates decreased, and 5-year survival rates increased. This fact indicates the effectiveness of the treatment of patients in this category. In more than 50 % of cases, the disease was detected at stage I of the pathological process, which is due to the proper level of diagnosis. The main medical and statistical indicators in patients with malignant bladder neoplasms in Saint Petersburg are comparable to the average Russian data, and in a number of parameters they exceed them.Conclusion. Oncourological assistance to the population with malignant neoplasms of the bladder in Saint Petersburg is provided properly. The study of medical and statistical indicators in dynamics can be used to improve the algorithms of medical and diagnostic care for cancer patients.
Correlation between 3D morphometric characteristics of kidney tumors and their histological structure
Authors: Fiev D. N. , Sirota E. S. , Kozlov V. V. , Proskura A. V. , Shpot E. V. , Chernenkiy M. M. , Chernenkiy I. M. , Puzakov K. B. , Azil’gareeva K. R. , Ismailov Kh. M. , Butnaru D. V. , Kutikov A. , Vinarov A. Z.
Published: August 2023

Aim. To assess the correlation between clinical characteristics (sex, age, and maximum tumor size), 3D morphometric characteristics of renal lesions obtained through processing of multispiral computed tomography data, and renal tumor histology.

Materials and methods. Evaluation of kidney tumor malignancy on the basis of comparative analysis of primarily morphometric characteristics of the lesion obtained through processing of multispiral computed tomography data and histological tumor structure is presented. Data of 308 patients (175 (56.8 %) males and 133 (43.2 %) females) with unilateral renal tumors were analyzed.

Results. Multivariable analysis showed that malignancy of kidney tumor is associated with sex (male), location in the middle segment, tumor size, tumor shape (spherical with conical base) (24.8 %), while mushroom-like lesion shape was more common in benign tumors (35.2 %). In univariate models, only two variables were statistically significant predictors: patient sex and tumor shape.

Conclusion. The developed logistic model based on analysis of such predictors as sex and kidney tumor shape has a high percentage (87.6 %) of correct predictions of tumor histological structure.
The first experience of using prostate cancer organoids as a model for personalized selection of drugs
Authors: Nikulin S. V. , Alekseev B. Ya. , Poloznikov A. A. , Osipyants A. I.
Published: August 2023

Background. A promising experimental approach to the personalized selection of treatment regimens is the study of the sensitivity of tumor cells to drugs in vitro on tumor organoids.Aim. To generate a culture of prostate tumor organoids and to assess the effectiveness of the chemotherapeutic drug docetaxel used to treat prostate cancer on this culture.Materials and methods. The initial tissue was dissociated using gentleMACS Octo homogenizer. Next, the cells were cultured in matrix Matrigel with addition of a serum-free complete nutrient medium. For histological analysis, organoids were fixed in a 10 % formalin solution, followed by staining with hematoxylin and eosin according to the standard protocol. Cell viability was assessed using MTS assay.Results. In this work, we generated a new culture of prostate cancer cells. The histological analysis confirmed that the resulting organoids consist of tumor epithelial cells. As a result of the cytotoxic test, it was shown that in this case docetaxel (82.9 %; p = 0.32) didn’t reduce statistically significantly the viability of prostate cancer cells compared to the control.Conclusion. The use of tumor organoids of prostate cancer for selection of an optimal treatment regimen is a promising experimental technology, however, further research is necessary for its introduction into practice.
Comparative analysis of 10-year functional outcomes of robot-assisted radical prostatectomy and radical retropubic prostatectomy. Experience of the Urology Clinic of the A.I. Evdokimov Moscow State University of Medicine and Dentistry
Authors: Ramazanov K. K. , Kolontarev K. B. , Ter-Ovanesov M. D. , Govorov A. V. , Vasilyev A. O. , Kazakov A. S. , Pushkar D. Yu.
Published: August 2023

Background. Prostate cancer is the 3rd most common diagnosis among malignant tumors. The first robot-assisted radical prostatectomy (RARP) was performed in 2001. Studies comparing RARP and radical retropubic prostatectomy (RRP) are limited. In Russia, the Da Vinci robot was first installed in 2007. At the Urology Clinic of the A.I. Evdokimov Moscow State University of Medicine and Dentistry the program of robot-assisted surgery started in November of 2008.Aim. To perform first in Russia evaluation of 10-year functional treatment outcomes for patients with localized prostate cancer after RARP. To perform comparative analysis with RRP outcomes.Materials and methods. Medical histories of 211 patients from the Urology Clinic of the A.I. Evdokimov Moscow State University of Medicine and Dentistry were analyzed. Among them, 62 patients did not satisfy the inclusion criteria. Therefore, the study included 149 patients who underwent surgical treatment for localized prostate cancer between January of 2009 and December of 2011. Depending on the technique of surgical intervention, patients were divided into 2 groups: 1st – RARP (n = 82), 2nd – RRP (n = 67). All RARP were performed by a single surgeon, RRP by 2 experienced surgeons (experience >1000 RRP).Results. Median follow-up was 120 months in both groups. Overall survival in the 1st and 2nd groups was 85.4 and 86.6 %, respectively (p >0.05). For accuracy of functional outcomes analysis, patients who died during follow-up were excluded from the study. Frequency of neurovascular bundle preservation in the 1st and 2nd groups was 60.9 % (50/82) and 40.2 % (27/67), respectively (p = 0.01). Erectile function was preserved in 60.0 and 44.4 % males of the 1st and 2nd groups, respectively (p = 0.01). Age below 60 years (р = 0.009) and disease stage рТ2 (p = 0.026) were predictors of erectile function preservation after RARP. Continence frequency was 92.7 and 82.1 % in the 1st and 2nd groups, respectively (p = 0.048).Conclusion. Ten-year comparative analysis shows that RARP allows to achieve significantly better parameters of urinary continence and erectile function preservation in men with localized prostate cancer than RRP.
Neuroendocrine prostate cancer
Authors: Safina S. Z. , Isyangulova A. Z.
Published: August 2023

In Russia, prostate cancer is a common disease with fast increasing incidence. In the vast majority of prostate cancer patients receiving hormone therapy, on average 18–36 months after the start of treatment refractoriness to androgen ablation develops. In 15–20 % of patients, signs of neuroendocrine differentiation may develop.Neuroendocrine prostate cancer is an aggressive variant of castration-resistant prostate cancer with poor prognosis and low survival.Due to the rarity of these types of tumors, specific diagnostic and treatment algorithms have not been developed. As a rule, they are similar to the methods for other malignant forms of prostate cancer and neuroendocrine tumors.
Development of Saponin based Nano emulsion formulations from Phaleria macrocarpa to Control Aphis gossypii
Authors: Anis S Mokhtar*, Nurhayo Asib Abdul Rehman Roonjho, Rita Muhamad Awang,
Published: August 2023

Aphis gossypii is one of the most devastating insect pests of agricultural crops due to its polyphagous nature. A sustainable environment friendly method to manage this pest is botanical aphicides because of their easily biodegradability and overall safety. In this study, saponin based nano emulsions from Phaleria macrocarpa with Termul 1284 and methyl oleate /rapeseed oil were formulated and tested against A. gossypii for their efficacy in both laboratory and glasshouse conditions.  Results exhibited that all three formulated nano emulsions effectively suppressed A. gossypii population under laboratory and glasshouse conditions. However, TR3 revealed highest repellency (62%) and mortality percentage (100%) with lowest LC50 (1516 mg-L1) and LT50 (27.50 h), following by TM1 repellency (58%) and mortality percentage (98%) with lowest LC50 (1732 mg-L1) and LT50 (34.43 h). Glasshouse bioassay also revealed that TR3 (Termul 1284+rapeseed oil) and TM1 (Termul 1284+methyl oleate) could suppress A. gossypii population at LC50 values of 2512 and 2904 mg-L1 at 72 hours and LT50 values of 68.7 and 71.2 hours at 10000 mg-L1 respectively. Therefore, these both formulations could be considered as eco-friendly alternative approach in pesticides technology.
Descriptive study of the species Limnophora Robineau-Desvoidy 1830 (Diptera:Muscidae) in Iraq – Kerbala
Authors: Haider Naeem Al-Ashbal Muna Ibrahim jassem, , Alhesnawi Asaad Sh. M.
Published: August 2023

The current study was conducted during the year 2020 in some areas of the holy Kerbala governorate with the aim of diagnosing some species of insects of environmental and biological importance and knowing their distribution and the time of occurrence during seasons. The results showed that the species Limnophora obsignata (Rondani, 1866) (Muscidae: Coenosiinae) was recorded for the first time in Iraq. It was found that throughout the study period, this species was more frequently found in river habitats and seasons with moderate temperatures and humidity (spring and autumn). The external appearance of this species was described, as well as the anatomy of the male reproductive system of the samples.
Automatic Digitization of JMA Strong-Motion Seismograms Recorded on Smoked Paper: An Attempt Using Deep Learning
Authors: Furumura Mitsuko , Ogawa Yoko , Sakamoto Kazuo , Matsu’ura Ritsuko S.
Published: August 2023

Using deep learning, an attempt was made to automatically digitize waveforms in scanned Japan Meteorological Agency (JMA) analog seismograms of strong-motion seismographs recorded on smoked paper. We manually traced the waveforms in the scanned images to be used as supervised data for a convolutional neural network (CNN) model using these images. In the analog recording system, ground shaking was recorded on paper with a needle attached to the end of an arm. Because the other end of the arm is fixed on a pivot, the needle moves in an arc around the pivot for large shaking compared to the arm length. We carefully considered the effects of the finite arm length in the analog system and trained the CNNs. To validate the learning results, the trained CNN model was applied to images that were not used for the training. The automatic digitization by our method works fairly well, except for seismograms rich in high-frequency components and those with long-period large amplitudes. Even these images can be well digitized by resizing the image height by, for example, 1/2. To further improve the accuracy of automatic digitization, it would be effective to prepare many additional input and supervised data, and retrain the model. Other training is also necessary for other types of seismographs that have features and characteristics different from strong-motion seismograms.
Humans versus Chatbots: Scaling-up behavioral interventions to reduce teacher shortages
Authors: Ajzenman Nicolás , Elacqua Gregory , Jaimovich Analia , Pérez-Nuñez Graciela
Published: August 2023

Empirical results in economics often stem from success in controlled experimental settings, but often fail when scaled up. This study presents a behavioral intervention and a scalable equivalent aimed at reducing teacher shortages by motivating high school students to pursue an education degree. The intervention was delivered through WhatsApp chats by trained human promoters (humans arm) and rule-based Chatbots programmed to closely replicate the humans program (bots arm). Results show that the humans arm successfully increased high-school students demand for and enrollment in education majors, particularly among high-performing students. The bots arm showed positive but smaller and statistically insignificant effects. These findings indicate that a relatively low-cost intervention can effectively reduce teacher shortages, but scaling up such interventions may have limitations. Therefore,testing scalable solutions during the design stage of experiments is crucial.
Cultura infantil, culturas infantis e culturas da infância: polissemias em debate
Authors: Botega Giovana Alonso , Moruzzi Andrea Braga
Published: August 2023

Este artigo apresenta definições e entendimentos sobre os conceitos cultura infantil, culturas infantis e culturas da infância, resultado da dissertação intitulada Cultura infantil, culturas infantis e culturas da infância: polissemias em debate. A dissertação realizou uma espécie de genealogia sobre os conceitos citados, no interior do campo da Sociologia da Infância. O artigo se empenha em apresentar o percurso metodológico pelo qual a pesquisa foi realizada, assim como as análises empreendidas, das quais apresentam-se, de modo geral, o seguinte resultado: o campo da Sociologia da Infância é um campo que caminha de forma tangencial ao da Educação, em especial ao da Educação Infantil. Na tentativa de estruturar o campo da Sociologia da Infância, notou-se um movimento muito particular no Brasil, inaugurado a partir dos estudos de Florestan Fernandes e impulsionado por teóricos e pesquisadores interessados pela infância, pela formação de professores, pelas práticas pedagógicas e por outras áreas, temas e campos similares.
Profissão Docente: adolescentes e adultos emergentes escolhem ser professores?
Authors: Dias Elaine Teresinha Dal Mas , Silveira Fernanda Caline Casemiro
Published: August 2023

Esta pesquisa tem como objeto a escolha da docência por adolescentes e adultos emergentes matriculados nos primeiros e segundos semestres de cursos de licenciaturas, públicos e privados, com a intenção de identificar e compreender as influências, as peculiaridades das experiências e das histórias de vida, e as determinações externas e internas que induziram a opção pela Educação. Emprega a abordagem qualitativa de investigação e utiliza-se de entrevistas abertas em aprofundamento, com quinze estudantes distribuídos por quatro áreas do conhecimento: Filosofia, Geografia, História e Letras. Destaca quatro Unidades de Significado - Adolescência e processo de escolha profissional, Identificação com o professor, O ambiente e a experiência escolar, Educação como ferramenta de transformação – associadas a Expressões Significativas correspondentes para apontar os elementos captados nas narrativas, com o intuito de demonstrar os percursos dos estudantes no processo de opção profissional. A epistemologia da complexidade, nas proposições de Edgar Morin, ancora a compreensão e as análise das narrativas, pautando-se, em especial, nos princípios operadores – hologramático, recursivo, dialógico, exclusão e inclusão -, nos complexos imaginários (PIT) e na compreensão humana. As análises, em movimento contrário às conclusões da literatura consultada acerca da temática, denotam que há ainda os jovens têm interesse em seguir a carreira e os principais influenciadores são os genitores e o grupo de iguais, em uma dinâmica projetiva-identificatória inspiradora. No ambiente escolar são os docentes que mobilizam o apreço pelo campo de trabalho e imprimem características pessoais ao ato educativo e possibilitam identificação e compreensão da função e do papel do educador, tanto em situações positivas como negativas, em um curso antagônico-complementar. Nota-se, majoritariamente, que a intenção é fazer da educação uma ferramenta de transformação social e educacional.
Percepções dos professores orientadores sobre as contribuições do Salão UFRGS Jovem para desenvolver habilidades e conhecimento científico dos alunos participantes
Authors: Bertoglio Lorenzoni Bruna , Miskinis Salgado Tania Denise
Published: August 2023

O presente artigo aborda as percepções dos professores orientadores a respeito da importância da pesquisa na educação básica e das contribuições da participação dos alunos no evento científico Salão UFRGS Jovem. O Salão UFRGS Jovem é uma atividade destinada aos alunos da educação básica e da educação profissional de nível médio, realizado na Universidade Federal do Rio Grande do Sul (UFRGS). A pesquisa, caracterizada como descritiva, teve como público-alvo professores participantes no Salão UFRGS Jovem entre o período de 2014 a 2019. Aplicou-se um questionário, enviado para 100 professores, via plataforma Google Docs, com retorno de 36 participantes. A partir das informações coletadas foi possível traçar o perfil deste público, como idade, escolaridade, tempo de docência, vínculo institucional, área do conhecimento que lecionam e o contato com a iniciação científica na sua formação. A análise das respostas permitiu verificar as contribuições do Salão UFRGS Jovem para os alunos quanto ao desenvolvimento de habilidades e ao conhecimento científico na opinião desses professores. Utilizou-se a análise de conteúdo de Bardin (2010) para análise das respostas. O estudo mostrou que os professores identificaram que o evento contribuiu para o desenvolvimento de 15 habilidades nos alunos. A habilidade mais destacada foi Apresentar, que segundo a Base Nacional Comum Curricular (BNCC) está no grupo da Compreensão, que é classificado como complexo. Referente à construção do conhecimento científico, verificou-se a ocorrência de 13 subcategorias, com predomínio da Motivação. Concluiu-se que a pesquisa deve ser incentivada nas escolas, assim como a sua divulgação em eventos científicos, por oportunizarem aos alunos o desenvolvimento de importantes habilidades e a apropriação do conhecimento científico.
Educação, igualdade e diversidade: Perfil dos professores do norte do Brasil egressos de cursos de Pedagogia
Authors: Gonzales Neidimar Vieira Lopes , Raitz Tânia Regina
Published: August 2023

Resumo: O Brasil é um país que contrasta riqueza e pobreza marcadamente visíveis nas suas cinco regiões. É possível perceber a desigualdade de condições e acesso aos bens econômicos, culturais e educacionais existente entre as regiões brasileiras. Considerando tais disparidades, este trabalho é recorte de uma tese e tem como objetivo apresentar o perfil socioeconômico de professores de Rondônia, região norte do Brasil, egressos de cursos de Pedagogia. Quanto a estrutura metodológica, trata-se de pesquisa analítica/descritiva de abordagem quanti-qualitativa, cuja interpretação prima pelo enfoque qualitativo. O instrumento utilizado para coleta de dados foi o questionário on line (google forms) aplicado a 48 egressos. Os estudos de Moret (2021), Arroyo (2011), Gatti et al. (2019) e Canclini (2011) foram fundamentais para o conhecimento histórico e análise crítica. Concluiu-se que o perfil socioeconômico dos egressos dos cursos de Pedagogia muito se assemelha ao perfil levantado pelo Relatório Síntese do curso de Pedagogia do Enade-2017, divergindo quanto a idade (entre 35 e 39 anos), mas convergindo na atratividade pela docência que ocorre como possibilidade de ascensão social. A feminização do magistério pode estar associada a construção social da diferença entre os sexos (dominação masculina). E que os resultados do Enade-2017 não estão sendo considerados para melhorar a qualidade da educação superior brasileira.
Educação inclusiva e o Ensino de Ciências: um estudo bibliográfico
Authors: Silva Stéfane da , Borges Dias Viviane , Silva Menezes Naiara , Siqueira Maxwell
Published: August 2023

Com a  chegada dos alunos com deficiência e/ou transtornos nas classes regulares, a escola precisa ser reestruturada para proporcionar um ensino que contemple a diversidade. Em relação ao Ensino de Ciências, é notório que essa área do saber apresenta certa complexidade, visto que seu papel não se restringe apenas a cumprir com questões curriculares, mas formar cidadãos críticos. Assim, levando em consideração a importância de ampliar as discussões envolvendo o Ensino de Ciências da Natureza (Biologia, Química e Física) e a Educação Inclusiva, esse trabalho objetiva mapear e analisar artigos publicados em revistas de Qualis A1 e A4 da área de Ensino de Ciências, que abordem o Ensino de Ciências e a Educação Inclusiva, no período de 2010 a 2022. Essa é uma pesquisa qualitativa, do tipo levantamento bibliográfico. Para a análise dos dados, foi realizada a leitura dos títulos e resumos, foram identificados 13  artigos.  Os resultados foram organizados nas seguintes categorias: a) referencial teórico e metodológico; b) distribuição das pesquisas nas áreas específicas das ciências da natureza  c) deficiências e /ou transtornos abordados nos trabalhos e  d) distribuição das pesquisas em relação ao eixo central das discussões. Assim, a investigação apontou que a maioria dos trabalhos apresentam uma discussão geral sobre a Educação Inclusiva e o Ensino de Ciências, sem um referencial teórico base. Foi possível identificar a predominância da deficiência visual, seguida da deficiência auditiva como pautas centrais nas discussões. Em relação as principais tendências das pesquisas, elas estão implicadas com as dificuldades encontradas para efetivar um ensino democrático, como é proposto pela educação inclusiva, por isso há uma necessidade de reestruturar as instituições de ensino. Os resultados encontrados se limitam aos periódicos encontrados e ao recorte temporal adotado, contudo, possibilita refletir sobre lacunas encontradas e a necessidade de ampliação das pesquisas na área.Palavras-chave: Ensino de Ciências; Educação Inclusiva; Revisão Bibliográfica.
“Eu sou porque nós somos”: Experiências do emocionar nas aprendizagens umbandistas
Authors: Chagas Wagner dos Santos
Published: August 2023

Resumo: O artigo apresenta os resultados da pesquisa que investigou os processos de aprendizagem nos espaços umbandistas. O objetivo principal da pesquisa foi analisar como acontecem os processos de aprendizagem na Umbanda, tendo como fundamentação teórica a perspectiva Ubuntu e a Biologia do Amor de Humberto Maturana. Como orientação metodológica utilizou-se a pesquisa qualitativa numa perspectiva de recortes de histórias de vida.  A produção dos dados foi realizada por meio de entrevista semiestruturada, com dez sujeitos de pesquisa de quatro espaços umbandistas da região metropolitana de Porto Alegre/RS. Os resultados indicam que nos espaços umbandistas as práticas religiosas não se separam das experiências de aprendizagem. Essas experiências de aprendizagem acontecem por meio da significação e ressignificação das práticas cotidianas que estão encharcadas pelos saberes tradicionais da Umbanda. Aprender na Umbanda é um processo de viver e conhecer em comunidade, em que os saberes tradicionais estão entrelaçados com as configurações do emocionar presente nos espaços umbandistas, representando uma grande diversidade epistemológica.
Роль волонтерской деятельности в формировании патриотических качеств у студенческой молодежи
Authors: Акимова Е.А. , Гапеев И.П.
Published: August 2023

Статья посвящена проблематике волонтѐрства в контексте важности продолжения патриотического воспитания молодѐжи в студенческом возрасте, как возрасте наиболее благоприятном для подобного рода деятельности. Выявлена и обоснована роль волонтѐрской деятельности как одного из ключевых инструментов формирования чувства патриотизма в новых поколениях.
Основы правильных движений при игре в теннис
Authors: Балашов М.С. , Илюшин О.В.
Published: August 2023

В данной статье описаны основы правильных движений для максимальной эффективности игры в таком виде спорта, как теннис.
Домашняя учебная работа как средство формирования познавательной активности младших школьников
Authors: Ворсобина Н.В. , Сулейманова Ф.Ш.
Published: August 2023

В статье анализируются виды домашней работы, рассматриваются средства формирования познавательной активности, а также специфика работы с домашними учебными заданиями. Показана возможность активизации познавательной активности младших школьников по предмету «Окружающий мир» средствами домашней работы.
Образовательный туризм как фактор обучения и воспитания студентов педагогических высших учебных заведений Краснодарского края
Authors: Гречишко Д.Н. , Ярина А.А.
Published: August 2023

В статье исследуется значение образовательного туризма в профессиональном становлении бакалавров педагогического образования. Анализируется сущность понятия «образовательный туризм», основные его элементы и формы реализации, а также влияние туристской деятельности на обучение и воспитание студенческой молодежи.
Фольклор в художественной литературе
Authors: Зайдиева Л.М
Published: August 2023

В данной статье нами рассматривается термин «фольклор» и его значимость в литературе. В основу работы положено изучение особенностей фольклорных произведений и их классификация. Раскрывается его роль в обыденной разговорной речи, в источниках словесной образности и в сказочной фантазии.
Современные тенденции развития студенческого спорта
Authors: Керницкая Д.Д.
Published: August 2023

В статье рассмотрены современные тенденции развития студенческого спорта при содействии спортивных студенческих клубах России. Раскрывается положительное влияние физической культуры на личностное развитие студенческой молодежи
Роль условно-графической наглядности и практика ее использования в обучении английскому языку в основном общем образовании
Authors: Киреева И.А. , Михеева Л.Д. , Гриб А.А.
Published: August 2023

Актуальность настоящего исследования обусловлена востребованностью анализа практики применения условно-графической наглядности в решении задач обучения английскому языку в основном общем образовании, учитывающей особенности определенной возрастной группы, и еѐ недостаточной практической разработанностью. Целью исследования является анализ роли условно-графической наглядности и практики ее использования в обучении английскому языку в основном общем образовании. Новизна исследования в статье состоит в изучении практики использования условно-графической наглядности в обучении грамматике английского языка учащихся VII – VIII классов. В результате было установлено, что овладение грамматическим материалом, подлежащим усвоению практическим путем в школе на основе использования условно-графической наглядности при формировании грамматических умений по английскому языку у учащихся VII – VIII классов, стало более рациональным и эффективным.
Способы и формы контроля эффективности использования интерактивной наглядности в экометодике обучения английскому языку учащихся в основном общем образовании
Authors: Киреева И.А. , Табарова А.Д. , Приданова М.В.
Published: August 2023

Актуальность исследования в статье обусловлена трансформацией и появлением новых видов контроля на основе использования мультимедийных технологий и средств обучения английскому языку в современной общеобразовательной школе. Целью исследования является рассмотрение способов и форм контроля эффективности использования интерактивной наглядности в экометодике обучения английскому языку учащихся в основном общем образовании. Новизна исследования в статье состоит в обозначении способов и форм контроля эффективности использования интерактивной наглядности в экометодике обучения английскому языку. В результате доказана значимость интерактивной наглядности в экометодике обучения английскому языку учащихся в основном общем образовании. Итоги и материалы работы могут быть использованы учителями иностранных языков при обучении английскому языку учащихся в основном общем образовании.
Дистанционные возможности в современном мире: новые вызовы и перспективы
Authors: Коган Т.И. , Акимова Е.А.
Published: August 2023

Бурное развитие информационных технологий привело к внедрению в учебный процесс компьютера как средства обучения. В статье рассматривается проблема дистанционного образования, специфика которого заключается в применении информационных технологий и учебных систем, обеспечивающих удаленный процесс передачи учебной информации для разных категорий учащихся, включая тех, кто не имеет возможности присутствовать на занятиях очно. С помощью дистанционного образования можно осуществлять не только процесс передачи информации, но и контролировать ее усвоение.
Шрифтовая композиция и особенности ее выполнения при обучении студентов
Authors: Крючков Е.М. , Уманова А.И. , Пилипер А.В.
Published: August 2023

В статье рассматривается специфика компоновки, построения, цветового решения, содержания и эмоциональной нагрузки при выполнении шрифтовой композиции, а также способы реализации при практическом исполнении.
Диагностика уровня сформированности коммуникативных компетенций у одаренных детей
Authors: Самбулова К.В.
Published: August 2023

Данная статья посвящена проблеме недостаточной сформированности коммуникативных компетенций у одаренных подростков. В работе выделены понятия одаренности, коммуникативной компетенции, ее структура, компоненты, а также особенности жизнедеятельности одаренных подростков, препятствующие полноценному формированию коммуникативных компетенций. Проведена диагностика коммуникативных и организаторских склонностей (КОС-2), приведены результаты и сформулирован вывод.
The development of university students’ self-organization with remote tutor support
Authors: Vlasova I.V.
Published: August 2023

The article studies remote tutoring as a possible resource for the development of selforganization components of university students. The concepts were given and revealed: selfrealization, support, tutoring, individualization, as well as methodological features were identified and the concept of remote tutor support was derived. It is concluded that self-determination, selforganization of university students is the subject of a tutor's work. Modern technologies, new social tools offer students access to knowledge, as well as the ability to interact with peers in the context of learning. Remote tracking has additional advantages: synchronicity and asynchrony; effective access to information; reducing social distance; open redundant educational environment.
Educational Value of Youtube Videos in Dialysis Catheter Application
Authors: ERCAN Zafer , GÜMÜŞ Fatih , ACAR Türkan , İSLAM Mahmud , DHEİR Hamad
Published: August 2023

Objective: Youtube is one of the most popular video-sharing websites and can be a powerful tool for disseminating health information. The number and use of Youtube videos in the medical field is increasing, so there is a need to research its educational value. We examined dialysis catheter application videos' characteristics, usefulness, and scientific accuracy. Methods: We performed a Youtube search with the keywords of "dialysis catheter" without selecting any filter in the English language in April 2022. The content of the videos, video sources, type of catheter mentioned in the video, presence of animation, and the accuracy of the information was evaluated. mDISCERN score was also determined to clarify the power of the accuracy. Results: The evaluation showed that the number of videos with accurate information was 171 (83.4%) with a significantly higher mDISCERN score (2.85±0.59). Among the targeted videos, the mDISCERN score of the videos uploaded by healthcare professionals and the official institution was significantly higher. The average usefulness score was 1.96±0.23, and there was no significant difference between the sources. Conclusions: It would be more appropriate to present the videos selected in terms of education and reliability under a sub-title such as "YouTube Medical Education" for use by medical professionals.
Supportive Environments Providing Social and Emotional Learning Explain Success in People with Learning Disabilities
Authors: DeBono Amber , English Julia , Heimbauer Michele , Mendelsohn Elizabeth , Cohen Jonathan
Published: August 2023

Although students with learning disabilities (SwLD) are at greater risk (compared to typical learners) for dropping out of high school, not attending college, and unemployment, some SwLD lead successful lives (Aro et al., 2019; Mazzotti et al., 2021; Wagner et al., 2005). Little, however, is known as to what factors support this subset of SwLD in defying the odds and achieving success by graduating from college and leading satisfying lives. Alumni from Winston Preparatory School (Winston), a school exclusively for SwLD that has a strong track record for high school graduation and college attendance, were recruited for this study. Results from a previous study on Winston alumni indicated all attended college and most: graduated college, were employed, and had someone who socially supported them. The present study described in this paper built on these findings. Results indicated that when students felt supported by teachers and people at home, they were more likely to report high levels of three social and emotional learning skills which predicted several measures of student success. These results may offer possible explanations for why certain SwLD succeed but more research, possibly longitudinal, is needed to gain a more thorough understanding of the factors involved.
Panorama dos instrumentos de planejamento e gestão da drenagem urbana no Brasil
Authors: Tsuji Thays Mitsuko , Carrara de Freitas Thiago Felipe , Rocha Pereira Alice , Uda Patrícia Kazue , Rodrigues Finotti Alexandra
Published: August 2023

O aumento do número de eventos extremos como consequência das mudanças climáticas têm agravado problemas e desastres associadas à drenagem urbana especialmente em climas tropicais e em localizações cuja urbanização ainda segue o modelo higienista. Para lidar com esses problemas, planejamentos bem feitos e executados são essenciais. Em termos de instrumentos legais de planejamento de drenagem urbana, a única exigência é que os municípios possuam planos municipais de saneamento básico (PMSB), estes por sua vez, costumam ser documentos volumosos o que dificulta a análise comparativa e global. Nesse sentido, esse trabalho teve como objetivo usar das análises de conteúdo para comparar e alcançar um panorama geral sobre como a drenagem urbana tem sido planejada. Portanto, utilizou-se do software de análise textual Iramuteq para a realização de análises quantitativas de 280 planos agrupados em quatro Corpora referentes aos estados do Mato Grosso, Amazonas, Bahia e municípios distribuídos pelo Brasil. Os resultados mostraram que nos estados do Mato Grosso e Amazonas, os planos não contemplaram os sistemas de drenagem urbana com a mesma relevância que os demais serviços do saneamento. Foram encontrados planos em que trechos dos textos apresentaram o mesmo número de ocorrência de termos com erros de grafia. Entre os termos mais frequentes não foram observados nenhum associado às terminologias de drenagem urbana sustentável.
Preservasi pengetahuan terhadap kegiatan katalogisasi literatur aksara Jawa di Perpustakaan Balai Bahasa DIY
Authors: Prabowo Thoriq Tri , Anjarwati Siwi , Rosita Mela
Published: August 2023

Cataloging Javanese script literature is a specific skill that cannot be done by everyone or librarians. This study aims to describe the efforts to preserve knowledge and good practices in the cataloging activities at the Perpustakaan Balai Bahasa DIY. We collected qualitative data by interview, non-participant observation, and documentation to collect data. Data analysis was carried out by collecting data, reducing data, presenting data, and drawing conclusions. The informants of this research are library coordinators and other related staff. The results of the study indicate that the preservation of tacit, explicit, and traditional knowledge is carried out at this institution. Knowledge preservation efforts need to be made into a structured activity so that the transfer of knowledge between librarians is more optimal.
Analisis Pemanfaatan E-book Sebagai Bahan Penunjang Pembelajaran Oleh Pengguna Perpustakaan SMAN 1 Kedungwaru Tulungagung
Authors: Prajawinanti Arin , Khoirunnisa Nita
Published: August 2023

Current technological advances lead us to rapid development. One of the developments that occurred was in the library. The information needs of library users are facilitated by the existence of e-books which can be used as learning support. . E-books are library materials in digital form which are considered as library materials that can be accessed whenever and wherever we need them. This research was conducted to find out how the use of e-book library materials as a support for learning at SMAN 1 Kedungwaru. The research method used in this study is qualitative and presented in a descriptive form using observation, interviews and documentation. Data analysis was carried out by collecting data, reducing data, presenting data, and drawing conclusions/verification. The results of the study show that students at SMAN 1 Kedungwaru have used e-books as a learning support. They use e-books as reading material to add insight. This is considered a practical matter to obtain learning materials, especially during a pandemic. The existence of this e-book also has a big influence on student academic achievement. E-books are also considered to make it easier for students to fulfill academic information. The results of this study also show that there are still students who have not been able to make full use of e-books. What's more, the collections provided are still limited, so students choose to look for library materials in physical form. However, librarians try their best to add library materials and carry out promotions so that students can make the most of e-books. E-book library materials can be put to good use and are also effective in utilizing the facilities provided. The e-book is used as a reference in supporting the learning process. The suggestion of this research is the need for encouragement or motivation so that users can make the most of e-books.
Penyuluhan Efek Penggunaan Smartphone Pada Anak Usia Dini
Authors: Prabowo Wahyu Adi , Arifa Amalia Beladinna , Nur Yohani Setiya Rafika
Published: August 2023

Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan orangtua dan anak-anak mengenai penggunaan gawai pada proses belajar mengajar di Srambi Paud Center Purwokerto. Penyuluhan dilakukan untuk membantu orangtua mengawasi penggunaan gawai oleh anak-anak mereka dalam kegiatan sehari-hari. Pelatihan ini diadakan di aula Srambi Paud Center Purwokerto dan berhasil meningkatkan pemahaman para orangtua dan anak-anak mengenai penggunaan gawai secara umum, serta memberikan pemahaman mengenai efek positif dan negatif yang dapat timbul akibat penggunaan gawai. Para peserta juga berhasil menerapkan hasil dari penyuluhan dengan mencari dan menggunakan media pembelajaran yang lebih bervariasi dan menarik perhatian anak-anak melalui gawai. Selain itu, kegiatan ini juga berhasil meningkatkan motivasi para guru dalam menciptakan bahan ajar yang menarik dengan memanfaatkan teknologi, sehingga memudahkan dalam penyampaian materi kepada anak-anak. Kegiatan praktik penyuluhan, para peserta diminta untuk mencari media pembelajaran melalui gawai dan membuat materi ajar untuk mata pelajaran yang sering diajarkan oleh masing-masing guru. Hasil praktik menunjukkan bahwa 95% guru mampu membuat media pembelajaran untuk anak-anak. Hasil kegiatan ini menunjukkan adanya peningkatan pengetahuan orangtua dan anak-anak mengenai penggunaan gawai serta memberikan manfaat yang signifikan bagi pembelajaran di Srambi Paud Center Purwokerto
Beyond the Umbrella: A Systematic Review of the Interventions for Prevention of and Reduction in the Incidence and Severity of Ovarian Hyperstimulation Syndrome in Patients Who Undergo In Vitro Fertilization Treatments
Authors: Palomba Stefano , Costanzi Flavia , Nelson Scott M. , Besharat Aris , Caserta Donatella , Humaidan Peter
Published: August 2023

Ovarian hyperstimulation syndrome (OHSS) is the main severe complication of the ovarian stimulation for in vitro fertilization (IVF) cycles. The aim of the current study was to identify the interventions for prevention of and reduction in the incidence and severity of OHSS in patients who undergo IVF not included in systematic reviews with meta-analysis of randomized controlled trials (RCTs), assess and grade their efficacy and evidence base. The best available evidence for each specific intervention was identify, analyzed in terms of safety/efficacy ratio and of risk of bias, and graded using Oxford Centre for Evidence-Based Medicine (CEBM) hierarchy of evidence. A total of 15 interventions to prevent OHSS were included in the final analysis. In IVF population not at high risk for OHSS, follitropin delta for ovarian stimulation may reduce the incidence of early OHSS and/or preventive interventions for early OHSS. In high-risk patients, inositol pretreatment, ovulation triggering with low doses of urinary hCG, and the luteal phase administration of GnRH antagonist may reduce the OHSS risk. In conclusion, even if not supported by systematic reviews with homogeneity of the RCTs, several treatments/strategies to reduce the incidence and severity of OHSS have shown to be promising.
A Soft Sensor Model Based on ISOA-GPR Weighted Ensemble Learning for Marine Lysozyme Fermentation Process
Authors: Lu Na , Wang Bo , Zhu Xianglin
Published: August 2023

The marine lysozyme fermentation process is a highly nonlinear, multi-stage, strongly time-varying system, making it hard to ensure model stability and prediction accuracy in the global scope by a conventional single global soft sensor model. To effectively solve the above problem, this study innovatively proposed a soft sensor modeling method based on an improved seagull optimization algorithm (ISOA) combined with Gaussian process regression (GPR) weighted ensemble learning. First, the sample data set is divided into multiple local sample subsets by the improved density peak clustering algorithm (ADPC). Second, the Gaussian process regression model is optimally altered with an improved seagull optimization algorithm for the purpose of establishing the corresponding sub-prediction model. Finally, the prediction model's fusion strategy is ultimately determined depending on the degree of connection between the test samples and a subset of local pieces. Simulation results show that the proposed soft sensor model can predict the key biochemical parameters of the marine lysozyme fermentation process well with less prediction error through fewer training data, which can be extended to soft sensor modeling of general nonlinear systems.
Phytocoenological, Ecological, and Eco-Protective Study on the Sustainable Development of the Ecosystem Vegetation Built by the Phytocoenoses of the Carici echinatae-Sphagnetum Association in the Vlădeasa Massif, Western Carpathians, Romania
Authors: Burescu Laviniu Ioan Nutu , Pop Iulia Florina , (Burescu) Morar Eugenia Adriana , Mateș Constantin Iosif , Vlad Ioana Andra
Published: August 2023

The purpose of this paper is to develop a phytosociological, ecological, cytogenetic, eco-protective and economic study of the vegetation of the wetland ecosystems in the Vlădeasa Massif built by the phytocoenoses of the association Carici echinatae-Sphagnetum (Balázs 1942) Soó 1955. In order to attain the aim and objectives put forward we carried out 10 phytocoenological surveys (surveys) in the phytocoenoses of the ecosystems during the optimal vegetation periods related to the summer-serotinal season in the timeframe 2020-2021. The taxonomically inventoried species were included in an association table by the criteria of their belonging to the basic coenotaxa of the association, alliance, order, vegetation class. The outcomes of the phytocoenosis research of the vegetation of the wetland ecosystems were processed, analysed, interpreted based on tables, histograms, diagrams, regarding the numerical and percentage weight of the species in the ecological categories of bioforms, phytogeographic elements (geoelements) and cytogenetic elements. The ecological behaviour of the species confined in ecosystems was also analysed by their relationship with ecological factors, edaphic soil moisture, air temperature and chemical reaction of the soil. The current state of ecosystems, potential threats, sustainable conservation of biodiversity, dynamics of phytocenoses, economic and scientific relevance were also subjected to research. The results obtained in the surveyed territory were analysed and compared numerically and as percentage with the data provided by two reference scientific works belonging to authors who independently carried out research with a similar topic in two different geographical regions of the Western Carpathians.
Development of Bedaquiline Loaded SNEDDS Using Quality by Design (QbD) Approach to Improve Biopharmaceutical Attributes for the Management of Multidrug-Resistant Tuberculosis (MDR-TB)
Authors: Jahan Rao Nargis , Solanki Pavitra , Akhtar Md Sayeed , Khan Zafar , Ahmad Farhan Jalees , Aqil Mohd. , Sultana Yasmin
Published: August 2023

Background: The ever-growing emergence of antibiotic resistance associated with tuberculosis (TB) has become a global challenge. In 2012, USFDA has given expedited approval to bedaquiline (BDQ), as a new treatment for drug-resistant TB in adults when no other viable options are available. BDQ is a diarylquinoline derivative and exhibits targeted action on mycobacterium tuberculosis but due to poor solubility desired therapeutic action is not achieved.
Objective: To develop a QbD-based self-nanoemulsifying drug delivery system of Bedaquiline using various oils, surfactants, and co-surfactants.
Methods: The quality target product profile (QTPP) and critical quality attributes (CQAs) were identified with a patient-centric approach which facilitated the selection of critical material attributes (CMAs) during pre-formulation studies and initial risk assessment. Caprylic acid as a lipid, propylene glycol as a surfactant and Transcutol-P as a co-surfactant were selected as CMAs for the formulation of Bedaquiline fumarate SNEDDS. Pseudo-ternary phase diagrams were constructed to determine the optimal ratio of oil and Smix. To optimize the formulation, a Box-Benkhen design (BBD) was used. The optimized formulation (BDQ-F-SNEDSS) was further evaluated for parameters such as droplet size, polydispersity index (PDI), percentage transmittance, dilution studies, stability studies, and cell toxicity through the A549 cell.
Results: Optimized BDQ-F-SNEDDS showed well-formed droplets of 98.88±2.1 nm with a zeta potential of 21.16 mV. In vitro, studies showed enhanced drug release with a high degree of stability at 25 ± 2 ºC & 60 ± 5 % and 40 ± 2 ºC & 75± 5 %. Furthermore, BDQ-F-SNEDDS showed promising cell viability in A549 cells indicating BDQ-F-SNEDDS as a safer formulation for oral delivery.
Conclusion: Finally, it was concluded that the utilization of a QbD approach in the development of BDQ-F-loaded SNEDDS offers a promising strategy to improve the biopharmaceutical properties of the drug, resulting in potential cost and time savings.