bluuebunny/crossref_metadata_2025 huggingface dataset:
Acute Oral Toxicity of Pinnatoxin G in Mice
Authors: Sosa Silvio , Pelin Marco , Cavion Federica , Hervé Fabienne , Hess Philipp , Tubaro Aurelia
Published: January 2020

Pinnatoxin G (PnTx-G) is a marine cyclic imine toxin produced by the dinoflagellate Vulcanodinium rugosum, frequently detected in edible shellfish from Ingril Lagoon (France). As other pinnatoxins, to date, no human poisonings ascribed to consumption of PnTx-G contaminated seafood have been reported, despite its potent antagonism at nicotinic acetylcholine receptors and its high and fast-acting toxicity after intraperitoneal or oral administration in mice. The hazard characterization of PnTx-G by oral exposure is limited to a single acute toxicity study recording lethality and clinical signs in non-fasted mice treated by gavage or through voluntary food ingestion, which showed differences in PnTx-G toxic potency. Thus, an acute toxicity study was carried out using 3 h-fasted CD-1 female mice, administered by gavage with PnTx-G (8–450 µg kg−1). At the dose of 220 µg kg−1 and above, the toxin induced a rapid onset of clinical signs (piloerection, prostration, hypothermia, abdominal breathing, paralysis of the hind limbs, and cyanosis), leading to the death of mice within 30 min. Except for moderate mucosal degeneration in the small intestine recorded at doses of 300 µg kg−1, the toxin did not induce significant morphological changes in the other main organs and tissues, or alterations in blood chemistry parameters. This acute oral toxicity study allowed to calculate an oral LD50 for PnTx-G equal to 208 μg kg−1 (95% confidence limits: 155–281 µg kg−1) and to estimate a provisional NOEL of 120 µg kg−1.
Emerging PCR-Based Techniques to Study HIV-1 Reservoir Persistence
Authors: Lambrechts Laurens , Cole Basiel , Rutsaert Sofie , Trypsteen Wim , Vandekerckhove Linos
Published: January 2020

While current antiretroviral therapies are able to halt HIV-1 progression, they are not curative, as an interruption of treatment usually leads to viral rebound. The persistence of this stable HIV-1 latent reservoir forms the major barrier in HIV-1 cure research. The need for a better understanding of the mechanisms behind reservoir persistence resulted in the development of several novel assays allowing to perform an extensive in-depth characterization. The objective of this review is to present an overview of the current state-of-the-art PCR-based technologies to study the replication-competent HIV-1 reservoir. Here, we outline the advantages, limitations, and clinical relevance of different approaches. Future HIV-1 eradication studies would benefit from information-rich, high-throughput assays as they provide a more efficient and standardized way of characterizing the persisting HIV-1 reservoir.
Genomic Characterization, Formulation and Efficacy in Planta of a Siphoviridae and Podoviridae Protection Cocktail against the Bacterial Plant Pathogens Pectobacterium spp.
Authors: Zaczek-Moczydłowska Maja A. , Young Gillian K. , Trudgett James , Fleming Colin C. , Campbell Katrina , O'Hanlon Richard
Published: January 2020

In the face of global human population increases, there is a need for efficacious integrated pest management strategies to improve agricultural production and increase sustainable food production. To counteract significant food loses in crop production, novel, safe and efficacious measures should be tested against bacterial pathogens. Pectobacteriaceae species are one of the causative agents of the bacterial rot of onions ultimately leading to crop losses due to ineffective control measures against these pathogens. Therefore, the aim of this study was to isolate and characterize bacteriophages which could be formulated in a cocktail and implemented in planta under natural environmental conditions. Transmission electron microscopy (TEM) and genome analysis revealed Siphoviridae and Podoviridae family bacteriophages. To test the protective effect of a formulated phage cocktail against soft rot disease, three years of field trials were performed, using three different methods of treatment application. This is the first study to show the application of a phage cocktail containing Podoviridae and Siphoviridae bacteriophages capable of protecting onions against soft rot in field conditions.
Infections, Vaccines and Autoimmunity: A Multiple Sclerosis Perspective
Authors: Jakimovski Dejan , Weinstock-Guttman Bianca , Ramanathan Murali , Dwyer Michael G. , Zivadinov Robert
Published: January 2020

Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease that is associated with multiple environmental factors. Among suspected susceptibility events, studies have questioned the potential role of overt viral and bacterial infections, including the Epstein Bar virus (EBV) and human endogenous retroviruses (HERV). Furthermore, the fast development of immunomodulatory therapies further questions the efficacy of the standard immunization policies in MS patients. Topics reviewed: This narrative review will discuss the potential interplay between viral and bacterial infections and their treatment on MS susceptibility and disease progression. In addition, the review specifically discusses the interactions between MS pathophysiology and vaccination for hepatitis B, influenza, human papillomavirus, diphtheria, pertussis, and tetanus (DTP), and Bacillus Calmette-Guerin (BCG). Data regarding potential interaction between MS disease modifying treatment (DMT) and vaccine effectiveness is also reviewed. Moreover, HERV-targeted therapies such as GNbAC1 (temelimab), EBV-based vaccines for treatment of MS, and the current state regarding the development of T-cell and DNA vaccination are discussed. Lastly, a reviewing commentary on the recent 2019 American Academy of Neurology (AAN) practice recommendations regarding immunization and vaccine-preventable infections in the settings of MS is provided. Conclusion: There is currently no sufficient evidence to support associations between standard vaccination policies and increased risk of MS. MS patients treated with immunomodulatory therapies may have a lower benefit from viral and bacterial vaccination. Despite their historical underperformance, new efforts in creating MS-based vaccines are currently ongoing. MS vaccination programs follow the set back and slow recovery which is widely seen in other fields of medicine.
Oblique Wave Attack on Rubble Mound Breakwater Crest Walls of Finite Length
Authors: Mares-Nasarre Patricia , van Gent Marcel R. A.
Published: January 2020

Rubble mound breakwaters usually present a crest wall to increase the crest freeboards without a large increase of the consumption of material. Methods in the literature to design crest walls are based on estimates of the wave loads. These methods are focused on the maximum loading that attacks a single position of the crest wall. In practice, crest walls have a finite length. Since the maximum loading does not occur at the same instant over the entire length of the crest wall for oblique waves, these methods overestimate the loading in the situation of oblique waves. Wave loads under oblique wave attack have been measured in physical model tests. A method to account for the effect of the finite length of crest walls has been developed, and design guidelines have been derived. The results of this study in combination with the existing methods in the literature to estimate the wave forces enable a more advanced design of crest walls.
Technical Note: A Device to Directly Measure Transpiration from Vegetation Grown in Containers
Authors: Pflug Stefanie , Voortman Bernard R. , Witte Jan-Philip M.
Published: January 2020

Information about evaporation and transpiration fluxes is vital for water budgets, modeling of water flows and climate, as well as for assessing the hydrological impact of land management practices. Under natural conditions, these fluxes are difficult to measure accurately, which results in large measurement inaccuracies. These inaccuracies can be reduced in controlled experiments. We present a device that is especially useful for transpiration studies conducted in large and/or heavy containers where weighing becomes too cumbersome or expensive. With our device we set a water table and control soil moisture of potted small trees by periodically replenishing soil water consumed by the tree, thereby measuring the inflow volume, which represent whole-tree transpiration. The device is made of inexpensive, easily available and durable materials and can be used for in- and outdoor experiments. Data acquisition is fast and easy. The mean measurement error of the device is 4.5% (±3.2% SD) for refill (i.e., transpiration) volumes of 1.5 L or larger. For a transpiring surface of 3 m², this amount is equal to an accuracy of 0.02 mm. Validation on field data showed that transpiration measured by the device is comparable to transpiration measured by gravimetric changes.
Chorological and Ecological Differentiation of the Commonest Leech Species from the Suborder Erpobdelliformes (Arhynchobdellida, Hirudinea) on the Balkan Peninsula
Authors: Marinković Nikola , Karadžić Branko , Slavevska Stamenković Valentina , Pešić Vladimir , Nikolić Vera , Paunović Momir , Raković Maja
Published: January 2020

This study is the result of extensive investigations of leeches on the Balkan Peninsula. Our aim was to detect actual and potential (modeled) distributions of common Erpobdellidae species, and to identify their ecological differentiation with respect to the altitudinal and waterbody type gradient. Although widespread, these species rarely live together. Intense competition is avoided by preferences for different types of habitats. This was confirmed by Pearson correlation analyses that yielded negative results. Differentiation of these species was clarified by the results of logistic Gaussian regression analyses. While Erpobdella octoculata and Dina lineata have a similar distribution along the altitudinal gradient, they prefer different waterbody types. Erpobdella vilnensis prefers higher altitudes than the other two species. Its preferred habitats are smaller rivers and streams located at altitudes from 400 to 1000 m a.s.l. Although present in all waterbody types, large lowland rivers and standing waterbodies are the preferred habitats of E. octoculata. Fast-flowing springs and streams are mostly inhabited by D. lineata. While the distribution of the species overlaps to a large degree, the ecological preferences of species differ significantly and thus they can be used as confident typological descriptors and indicators of ecological status.
Optimization of the Design of Water Distribution Systems for Variable Pumping Flow Rates
Authors: Martin-Candilejo Araceli , Santillán David , Iglesias Ana , Garrote Luis
Published: January 2020

Water supply systems need to be designed in an efficient way, accounting for both construction costs and operational energy expenditures when pumping is required. Since water demand varies depending on the moment’s necessities, especially when it comes to agricultural purposes, water supply systems should also be designed to adequately handle this. This paper presents a straightforward design methodology that using a constant flow rate, the total cost is equivalent to that of the variable demand flow. The methodology is based on the Granados System, which is a very intuitive and practical gradient based procedure. To adapt it to seasonal demand, the concepts of Equivalent Flow Rate and Equivalent Volume are presented and applied in a simple case study. These concepts are computationally straightforward and facilitate the design process of hydraulic drives under demand variability and can be used in multiple methodologies, aside from the Granados System. The Equivalent Flow Rate and Equivalent Volume offer a solution to design procedures that require a constant flow regime, adapting them to more realistic design situations and therefore widening their practical scope.
Beras Coklat Berkecambah (Germinated Brown Rice): Proses Produksi dan Karakteristiknya
Authors: Munarko Hadi , Sitanggang Azis Boing , Kusnandar Feri , Budijanto Slamet
Published: January 2020

Beras coklat diketahui memiliki komponen bioaktif yang bermanfaat bagi kesehatan. Namun, konsumsi beras coklat di masyarakat saat ini memang masih rendah dibandingkan dengan beras putih. Hal ini disebabkan beras coklat memerlukan waktu pemasakan yang cukup lama, memiliki tekstur agak keras, dan berbau yang kurang disukai. Beras coklat berkecambah atau dikenal dengan germinated brown rice (GBR) merupakan beras coklat yang telah mengalami perendaman dan perkecambahan pada kondisi tertentu. Perkecambahan mampu meningkatkan kandungan senyawa bioaktif beras coklat. Salah satu senyawa bioaktif yang dapat meningkat selama perkecambahan adalah senyawa gamma-aminobutyric acid (GABA). GABA berfungsi sebagai penghambat neurotransmitter di otak yang secara langsung mempengaruhi kepribadian dan manajemen stres. Peningkatan kandungan GABA pada beras coklat berkecambah dapat dilakukan dengan mengoptimalkan kondisi proses perendaman dan perkecambahan seperti suhu, waktu, pH, maupun penambahan senyawa lainnya seperti asam glutamat. Selama proses perkecambahan terjadi perubahan-perubahan biokimia yang diakibatkan oleh aktivitas enzim endogenus yang mengubah komponen makromolekul menjadi komponen yang lebih sederhana. Selain itu, perkecambahan pada kondisi tertentu juga dapat mengakibatkan perubahan fisikokimia GBR. Dengan demikian, perkecambahan juga dapat memperbaiki karakteristik sensori nasi yang dihasilkan, terutama atribut flavor dan tekstur.
How primary care can help survivors of transient ischaemic attack and stroke return to work: focus groups with stakeholders from a UK community
Authors: Balasooriya-Smeekens Chantal , Bateman Andrew , Mant Jonathan , De Simoni Anna
Published: January 2020

Background

Evidence about how primary care can best enable survivors of transient ischaemic attack (TIA)/stroke return to work is limited.

Aim

This study explored the role of primary care in supporting survivors of transient ischaemic attack (TIA)/stroke return to work with stakeholders from a local UK community.

Design

A qualitative study using framework analysis.

Method

Four focus groups were carried out in Cambridgeshire, UK, between September and November 2015. The 18 participants included survivors of TIA/stroke, carers, an employer representative, GPs, occupational therapists (OTs), and clinical commissioners.

Results

There was a mismatch between patient and carer needs and what is provided by primary care. This included: lack of GP awareness of invisible impairments; uncertainty how primary care could help in time-limited consultations; and complexity of return-to-work issues. Primary care physicians were not aware of relevant services they could refer patients to, such as OT support. In addition, there was an overall lack of coordination between different stakeholders in the return-to-work process. Linking with other services was considered important but challenging because of ongoing changes in service structure and the commissioning model. Suggestions for improvement include: a central contact in primary care for signposting to available services; a rehabilitation assessment integrated with the electronic record; and a patient-held shared-care plan at discharge from stroke wards.

Conclusion

Improving the role for primary care in helping survivors of TIA/stroke return to work is challenging. However, primary care could play a central role in initiating/coordinating vocational rehabilitation. Through focus group discussions with stakeholders from a local community, patients, carers, and clinical commissioners were able to put forward concrete proposals to address the barriers identified.
Тюрма у міському просторі Вінниці (кінець ХІХ – початок ХХ ст.): локація та внутрішній устрій
Authors: Кузіна К.
Published: January 2020

Стаття присвячена історії Вінницької міської тюрми. На підставі архівних документів, що вводяться до наукового обігу вперше, проаналізовано такі аспекти: розташування в’язниці у міському просторі; діяльність адміністрації щодо організації тюремного життя; повсякденне життя в’язнів; відносини церкви та тюрми. Дослідження є мікроісторичним, у центрі уваги якого конкретні форми соціальних практик.
«Прагнення реформ»: тюремні перетворення у Великій Британії у 70–х роках XVIII століття
Authors: Сокальська О.
Published: January 2020

У статті проаналізовано суспільно-політичні умови, що призвели до перегляду  англійської  системи  покарань,  визначено  причини  та  етапи  тюремних  перетворень  у  Великій  Британії  у  70-х  роках  XVIII  ст.,  окреслено  ідеї  та погляди філософів, філантропів та правників (Семюеля Денна, Вільяма Сміта, Джонаса  Хенуея,  Вільяма  Ідена,  Вільяма  Блекстона  та  ін.)  щодо  модернізації тюрем,  їх  внесок  у  формування  концепту  виправного  покарання.  Особлива увага приділена процесу розробки та основним положенням тюремних актів 1774 р., Акта про халки 1776 р., законопроєкту про каторжну працю 1778 р. та Пенітенціарного акта 1779 р.
Жандарм Феофіл Рожанов та його «Історія»
Authors: Ярмиш О. , Бернадський Б.
Published: January 2020

У статті розглядається кадрова політика органів політичного розшуку Російської імперії на прикладі одного з його офіцерів Ф. Рожанова. Аналізуються політико-правові погляди, що панували у російських спецслужбах, на прикладі «Історії революційного руху», підготовленої Ф. Рожановим. Автори спиралися на широке коло джерел, серед яких помітне місце посідають архівно-документальні матеріали, частина з яких уперше вводиться до наукового обігу.
Про роль заборонених у місцях позбавлення волі предметів у механізмі вчинення злочинів засудженими
Authors: Махніцька К.
Published: January 2020

У статті йде мова про таку умову, що сприяє вчиненню злочинів засудженими до позбавлення волі, як наявність у цих осіб заборонених предметів, речовин і засобів, а також про деякі шляхи її усунення, блокування, нейтралізації тощо
Heritability and Variability of Quality Parameters of Tomatoes in Outdoor Production
Authors: Zörb Christian , Piepho Hans-Peter , Zikeli Sabine , Horneburg Bernd
Published: January 2020

The tomato is the most important vegetable globally. In England, outdoor tomatoes are widely grown by amateur gardeners, with the number of their allotment plots exceeding 150000. For instance, in Germany, only about 16% of tomato plants are cultivated according to organic standards, although these rates are expected to increase. Breeding for yield and fruit quality can increase resource efficiency. Therefore, we need to evaluate the variability of yield and fruit quality parameters, to calculate the heritability of these traits and to identify superior genotypes for organic outdoor tomato production and breeding. With these aims, we grew 24 tomato genotypes of diverse origins in a two-year field trial. The heritability of quality traits such as glucose, fructose, organic acid, and lycopene was high. The medium heritability for yield suggests that trials with a larger number of locations are needed for the reliable selection of this character. Negative correlations of sugar concentrations with fruit weight and of organic acid concentration with fruit weight and yield suggest trade-offs in breeding for larger fruits and higher yields. Breeding for increased lycopene content is not subject to these challenges; the concentrations of the primary metabolite sugars and organic acids are positively correlated.
Impacto de la biblioteca académica en la enseñanza y el aprendizaje de los estudiantes universitarios, la investigación académica y la visibilidad del conocimiento:
Authors: Cabral Vargas Brenda
Published: January 2020

En las últimas dos décadas, determinar la contribución que las bibliotecas académicas (BA) tienen en las funciones sustantivas y en el logro de la misión de la universidad, se ha transformado en una prioridad a nivel internacional en el ámbito de la educación superior. En este artículo se presenta un modelo de evaluación de BA basado en tres dimensiones y 43 indicadores estratégicos que permiten valorar de manera integral a la biblioteca; entre los cuales se proponen ocho indicadores que están diseñados específicamente para medir los impactos respecto al “valor “que agregan a: la gestión del aprendizaje (GA), la gestión de la investigación (GI) y la gestión del conocimiento (GC).
PROTOTYPE OF E-OFFICE ADMINISTRATION LETTER SYSTEM IN GENERAL PART OF GOVERNMENT OF TANGERANG REGENCY
Authors: Fadilah Wafah
Published: January 2020

Along with the development of information and communication technology today, the internet has become a powerful tool to rethink the government system with a new model. However, the application of information technology has not been fully implemented in all fields in the government. One of them is in the General Section of the Regional Secretary of the Tangerang Regency Goverment which still manage the administration of the mail manually and archives the letter data that is still stored in Microsoft Excel. So for that it is necessary to make an information system that can help the work of the General Section Regional Secretary of the Tangerang Regency in managing and filing data letters. The infromation ssytem that will be built later will store data letters that have been inputted into the database so that the stored data will be safer and easier when searching for data. E-Office is a system related to office administration that is done electronically and uses the help of communication device and information system. With the creation of this system, it will be able to assist in the administration of correspondence to make it easier, faster and more accurate
EFFECTIVENESS OF FEATURED PRODUCT OF RURAL AREAS PROGRAM (PRUKADES) IN IMPROVING THE ECONOMY OF TELUK VILLAGE COMMUNITY PANDEGLANG REGENCY
Authors: Aulia Rida , Sururi Ahmad , Sukendar Sukendar
Published: January 2020

The purpose of this study was to analyze on how the effectiveness of the Featured Product of Rural Areas Program (Prukades) in improving the economy of rural communities and to determine on how the level of success of Featured Product of Rural Areas Program (Prukades) in improving the economy of the community. This study used descriptive study with analytical descriptive approach. The technique of collecting data was conducted by using interviews, observation and questionnaire. Respondents in this study were 23 respondents who are actively involved in Prukades with data analysis techniques that were used to measure the effectiveness of Prukades by using simple statistical methods and the submission of questions presented in the form of a questionnaire, then of the response is given a score. These results indicated that the program of Prukades in Teluk Village of Pandeglang Regency, included into the category of quite effective. Referring to the four indicators of the effectiveness used, that are the appropriate targeting, socialization, objectives and monitoring, the indicator of monitoring conducted by the part of DPMPD remains a constraint for the community, because even though it is regularly checked, people still do not feel the impact. And the success level of Prukades program is indicated by the absorption of 20 members who joined from three types of Prukades in Teluk Village.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI IMPOR BERAS DI KABUPATEN BERAU
Authors: Ningsih Sulami
Published: January 2020

Peningkatan jumlah penduduk akan meningkatkan jumlah konsumsi beras. Di sisi lain produksi beras walaupun meningkat, tetapi tetap belum dapat mencukupi kebutuhan akan beras di Kabupaten Berau. Oleh karena itu guna mencukupi kebutuhan akan beras, maka didatangkan beras dari luar daerah. Penelitian ini berjudul Analisis Faktor- faktor yang Mempengaruhi Impor Beras dio Kabupaten Berau.Tujuan penelitian ini adalah  untuk mengetahui korelasi produksi beras, konsumsi penduduk, jumlah penduduk dan kurs terhadap impor beras di Kabupaten Berau dan untuk mengetahui pengaruh produksi beras, konsumsi penduduk, jumlah penduduk dan kurs secara parsial dan serentak terhadap impor beras di Kabupaten Berau.Penelitian dilakukan dari bulan desember 2017 sampai Maret 2018 dengan menggunakan data sekunder yang berasal dari Badan Pusat Statistik  Kabupaten Berau, Dinas Pertanian dan Peternakan Kabupaten Berau, Dinas Pangan Kabupaten Berau, Bank Indonesia dan Kantor Bulog Kabupaten Berau  berupa data dari tahun 2007 sampai 2017. Analisa data menggunakan metode Regresi Linier Berganda dengan program SPSS versi 22.Hasil analisa data menunjukkan bahwa terdapat variabel exclude, yaitu konsumsi penduduk sehingga variabel bebasnya berkurang satu dan terdiri dari variabel produksi beras, jumlah penduduk dan kurs.Hasil penelitian menunjukkan bahwa impor beras di Kabupaten Berau 87,7 persen dipengaruhi oleh variabel (X1–(-0,614*Lag(X1)) ; (X3–(-0,614*Lag(X3)) dan  (X4–(-0,614*Lag(X4)) sedangkan 12,3 persen dipengaruhi oleh variabel lain . Model regresi yang dihasilkan adalah      Y-(-0,614*Lag(Y)) =167908,194 + 4,372 (X1-(-0,614*Lag(X1)) - 1,320(X3–(-0,614*Lag(X3)))     + 7,011 (X4-(-0,614*Lag (X4))) + e. dari nilai signifikan F Change adalah 0,001 yang berarti model ini dikatakan valid. Dari uji parsial diketahui bahwa masing- masing variabel bebas yaitu (X1–(-0,614*Lag(X1)) ; (X3–(-0,614*Lag(X3)) dan  (X4–(-0,614*Lag(X4)) secara parsial dan serentak memberikan pengaruh yang signifikan terhadap variabel terikat yaitu Y-(-0,614*Lag(Y). Kata Kunci :Produksi beras, konsumsi penduduk, jumlah penduduk , kurs, impor beras.
Sistem Informasi Akuntansi Kas Kecil Menggunakan Metode Dana Berubah
Authors: Pratama Fidya Arie , Rahaningsih Nining , Nurhadiansyah Nurhadiansyah , Purani Lili
Published: January 2020

Based on the results of observations made, it was found that the lack of research locations have not been able to produce financial statements presentation about petty cash expenses accurately, quickly, and accurately. That is because there is no accounting information system that covers the process of receiving and disbursing petty cash. At present in the presentation of petty cash financial statements still use Microsoft Office Excel where the summing errors can occur due to accidental deletion of the formula, resulting in the addition of errors that are more difficult for beginners to learn. The change fund system method is a system in which the amount of the petty cash fund changes according to the expenditure and receipt or addition of petty cash. In designing this information system using methods with the stages of Requirements analysis, Data modeling, Normalization. This study also uses the PHP (Hypertext Preprocessor) programming language, XAMPP, my sql, sublime text 3, Microsoft Office Vision and data obtained from the results of data collection at the research location. This petty cash accounting information system is made so that the process of presenting financial statements about petty cash expenditures that are urgently needed by the company can be done easily, quickly, accurately, effectively, and efficiently in order to avoid waste and fraud. This accounting information system is designed to manage expenses and receipts or additions to petty cash that are sufficient to monitor and control petty cash expenditures.
Sistem Monitoring Pintu Air Bendungan Menggunakan Mikrokontroler Wemos D1 R1 Berbasis Website
Authors: Rais Rais , Sabanise Yerry Febrian
Published: January 2020

Floodgate monitoring is related to water level monitoring. Problems that occur Weir information about the water level, water runoff, level, status of floodgates and recap results that can be seen on the web in real-time are not yet available, so monitoring the floodgates is difficult, less effective and maximum. Weir officials must go back and forth from the weir to the guard post and then to the control to move the floodgates. The purpose of the design of a sluice monitoring system is based on the website. Assist officers in monitoring floodgates to make it more effective and maximal. Using Wemos D1 R1 Microcontroller, Ultrasonic Sensor HC-SR04 to read water level, DC Motor moves the floodgates. LCD displays runoff and level. Siren as a danger warning. The trial results show that the system that has been made runs well. The system is able to open the floodgates through control of the web and runs automatically. Water runoff and level can be displayed on the LCD. Weir information about water levels, water runoff, levels, sluice status, and recap results can be viewed on the web in real time.
Transplante dental autógeno como alternativa á reabilitação oral
Authors: Fonseca Thais da Silva , Silva Rafael Lopes Quadros da , Hage Caio de Andrade , Ferreira Diego Pacheco
Published: January 2020

Objetivo: Reportar um caso clínico de transplante dentário autógeno associado à contenção com fio de sutura e descrição dos passos cirúrgicos. Materiais e métodos: Um indivíduo submetido a transplante de terceiro molar inferior para um alvéolo de primeiro molar inferior com comprometimento de erupção por dilaceração radicular avançada, através de exodontia pela técnica de incisão em envelope, seguido de contenção com fio de sutura por um período de uma semana. Resultados: O dente transplantado obteve satisfatória acomodação no novo alvéolo, uma vez que ao acompanhamento de 12 meses apresentou seguimento da rizogênese, ausência de bolsas periodontais, anormalidade pulpar e inexistência de mobilidade dentária.  Conclusões: Perante a técnica cirúrgica utilizada e indicações adequadas, observou-se terapêutica de baixo custo e biologicamente viável - por não comprometer o seguimento da formação radicular - como solução em caso de reabilitação oral.
Previsibilidade na instalação imediata de implante Cone Morse pelo planejamento digital e provisionalização imediata: relato de caso
Authors: Reyes Ángel José Sánchez , Thomé Geninho , Cartelli Carolina Accorsi , Bernardes Sérgio Rocha , Moura Marcos Boaventura de , Trojan Larissa Carvalho
Published: January 2020

A instalação imediata de implantes em região estética é uma prática frequente, pois reduzir a remodelação óssea e tecidual. Os implantes com interface cone Morse apresentam resultados biológicos e estéticos satisfatórios a longo prazo, pois apresentam gap reduzido entre implante e componente protético e a interface fica distante do tecido ósseo. Este artigo tem como objetivo relatar a reabilitação estética de um incisivo central superior comprometido através da instalação de um implante cone Morse utilizando a técnica da cirurgia guiada com provisionalização imediata. Paciente com 40 anos de idade, do sexo masculino, apresentava incisivo central superior (#21) com tratamento endodôntico prévio, recessão gengival vestibular, escurecimento coronário e mobilidade. O caso clínico apresentado mostrou que, após 12 meses, resultados precisos e estéticos são possíveis de alcançar com a instalação de implantes em alvéolos pós-extração e instalação de um dente provisório imediato em regiões estéticas.
Tratamento conservador de fratura condilar alta: relato de caso
Authors: Rodrigues Cristovão Marcondes de Castro , Santos Daniela Meneses , Oliveira Mirlany Mendes Maciel , Silva Marcelo Caetano Parreira , Furtado Lair Mambrini
Published: January 2020

Objetivo: Este trabalho tem como objetivo descrever um caso clínico de paciente com fratura côndilar tratado de forma incruenta com acompanhamento de dezoito meses. Relato de caso: paciente jovem, do sexo masculino, vítima de acidente motociclístico evoluindo com mordida aberta anterior, limitação da abertura bucal, dor bilateralmente nas articulações temporo-mandibulares, ausência de excursão dos côndilos em abertura, limitação dos movimentos de lateralidade e protrusão mandibular. Foram realizados exames de imagem e diagnosticado com fratura bilateral de côndilo alta. A conduta adotada foi a realização de instalação de barra de erich bimaxilar e bloqueio maxilo-mandibular por 21 dias, posterior instalação de elásticos para guiar oclusão, fisioterapia intensiva e acompanhamento ambulatorial mensalmente. Considerações finais: mesmo com as distintas vertentes literárias quanto ao tratamento das fraturas côndilares, o tratamento fechado mostra-se eficaz, sendo de consenso que o diagnóstico precoce, intervenção imediata e retorno extemporâneo das atividades funcionais, visando promover um melhor prognóstico no tratamento de fraturas.
Influência do uso da irrigação durante o acabamento e polimento de resinas compostas: rugosidade superficial, estabilidade de cor e morfologia de superfície
Authors: De Freitas Marcus Vinicius Nadler Mendonça dos Reis Perillo , De Freitas Denise Tavares Nadler Perillo , De Almeida Letícia Nunes , Magalhães Ana Paula Rodrigues , Cardoso Paula de Cavalho , Decurcio Rafael de Almeida
Published: January 2020

Objetivo: Avaliar rugosidade superficial (RS), estabilidade de cor (EC) e morfologia de superfície (MS) de um compósito nanoparticulado após diferentes protocolos de acabamento/polimento com ou sem irrigação. Material e métodos: Cem espécimes foram confeccionados e divididos em 10 grupos (n=10) conforme protocolo de acabamento/polimento: Tira de poliéster; discos abrasivos (DA); DA+espirais (DAE); DA+multi-laminada+espirais (DAME); espirais (E); e nenhum polimento. Protocolos com DA, DAE, DAME, e E foram realizados a seco e com irrigação. Após acabamento/polimento, os espécimes foram armazenados em água destilada à 37°C. Durante 14 dias, cinco espécimes de cada grupo foram imersos em café por 5min/dia. A EC foi analisada com Espectrofotômetro (CIEL*a*b*) 0, 7 e 14 dias após armazenamento em água ou imersão em café. A RS foi analisada com Rugosímetro (parâmetro Ra) e MS foi analisada com Microscopia Eletrônica de Varredura (MEV). ANOVA, Tukey e Teste T foram realizados para comparações entre os grupos (α=0,05). Resultados: A irrigação promoveu maior EC nos protocolos DAE e E. Os diferentes protocolos promoveram variação de cor semelhante após 14 dias de armazenamento em água. O protocolo E a seco promoveu os maiores valores RS, sendo inferior ao grupo DAME, que promoveu menor rugosidade e foi semelhante aos demais protocolos. Para DAME e E a irrigação foi significativa para diminuir a rugosidade. Na análise por MEV, E com irrigação apresentaram maior lisura superficial. Conclusão: A irrigação durante acabamento/polimento influencia na EC, RS e MS de compósitos. Os protocolos de acabamento/polimento DAME e E com irrigação foram mais efetivos.
La evolución de gobierno electrónico mexicano para institucionalizar la comunicación electrónica gubernamental
Authors: Portillo Barraza Selene
Published: January 2020

En este texto se hace una revisión de la evolución de los portales del gobierno electrónico federal de los Estados Unidos Mexicanos, desde la mención del sexenio de Vicente Fox hasta el actual, el de Andrés Manuel López Obrador, uniendo los parámetros entregados por la ONU en diferentes ocasiones en sus mediciones globales para los estudios de gobierno electrónico en diferentes países con el fin de evaluar la importancia de los programas gubernamentales y de la necesidad de que se le informe al ciudadano de las acciones de gobierno de forma expedita.
Humanizar la tecnología. Implicaciones culturales y formativas de la comunicación
Authors: Castro Rosales Elba Aurora
Published: January 2020

Reseña de libro.
America Latina aportes lexicos al italiano contemporaneo
Authors: López Castro Cruz Hilda
Published: January 2020

This work is a historical-etymological analysis of neologisms and linguistic borrowings from American Spanish, penetrated into the contemporary Italian language. Through an extensive lexicographic inventory, the author attempts to determine if Spanish can be considered the second foreign language that has had the most influence on Italian in the second half of the 20th century. The first chapter -the most important of the volume- analyses six semantic fields: politics, Liberation Theology, music (Andean and Afro-Caribbean), typical drinks, soccer, and drug trafficking. The telenovela lexical unit is also analysed.
Palazzi senesi tra '600 e '700
Authors: Rovida Maria Antonietta
Published: January 2020

The theme of residential architecture in Siena between the 17th and 18th centuries is directly linked to a central historiographical issue concerning modern age Siena, that is, the relationship between Siena’s aristocracy and the Medici power. In fact, starting from the the second half of 17th century it is possible to observe an intensification of urban residential building interventions, with restructuring activities and new constructions, that is directly linked to the social and political representation needs of Siena’s aristocratic class. The book examines in particular some buildings, whose unpublished documents have been recently the object of study of new researches.
Wir Kinder. La questione del potere nelle relazioni adulti/bambini
Authors: Spinosi Nicola
Published: January 2020

The relationships between adults and children requires the presence of two parties involved, but one of the two, the children, has all the rights on their side, while the other, the parents, the adults, has all the duties and many responsibilities towards the first. "Who has the power?". This is the question around which the essays in this volume revolve: they are dedicated to the analysis of the relationships between adults and children as a question of “power”, considered on Foucault’s basis not as something that is shared between those who possess it and those who suffer it, but as something that “circulates”. The analysis is carried out not only through the work of childhood and family historians, the critique of Freudian psychoanalysis, and Gregory Bateson’s theory on the “double bind”, but above all through the reading of works of Italian (Collodi, De Amicis, Vamba) and foreign fiction (Flaubert, Kafka, Bernhard).
Le «cognizioni inutili»
Authors: Monserrati Michele
Published: January 2020

The project of the periodical “Lo Spettatore fiorentino” (“The Florentine Spectator”) is a surprising attempt to challenge the ideology of progress using the typical means of that propaganda. With an ironic and cutting style, Leopardi addresses the varied audience of newspaper readers to help them recognise the unhappiness of living and, at the same time, share with them the “pleasure of the useless”. The light and moralistic tone of the Manifesto takes up the model of eighteenth-century publications, in particular the newspapers of Gaspare Gozzi. But the eulogy of the useless prefigures the deeds of the flâneur, a character who represents a suggestive interpretation key of the latest works by Leopardi.
Censura, istituzioni e politica letteraria in URSS (1964-1985)
Authors: Zalambani Maria
Published: January 2020

Soviet society has always been characterised by a marked institutional censorship which, in the face of the power of the written word, has set in motion a series of highly repressive institutions. However, censorship does not necessarily exert its power through forms of coercion; there are also approaches that are implemented through a complex network of cultural institutions that can "produce" society, expunging concepts and attitudes that are a threat to the system and at the same time masterminding a series of organisms designed to forge orthodox behaviour and mindframes, to the extent that the role of the external censor often becomes almost superfluous, being replaced by the "censor of the soul". This book seeks to bring to the fore this second type of censorship, albeit without neglecting the complex repressive machinery set in motion by Soviet power.

Press Review:
Il Giornale, L'INTERVISTA - MARIA ZALAMBANI: «Così Breznev censurò persino Sartre» a cura di Giuseppe Ghini, 19/04/2010
Dalle esigenze alle opportunità
Authors: Ercolini Michele
Published: January 2020

The volume aims to create an idea of the river landscape project as a cultural and social investment, to attain a “control” of a landscape transforming itself, while maintaining harmonious forms and sustainable structures from an ecological-environmental point of view; a landscape that continuously redesigns itself, based on human needs without overwhelming nature. The need to primarily safeguard river hydraulic over infrastructure thus becomes an opportunity for a “third landscape” project, an opportunity to transform “non-places” into “places”.
Tra economia e politica: l'internazionalizzazione di Finmeccanica, Eni ed Enel
Authors: Renda Francesco , Ricciuti Roberto
Published: January 2020

In an economic system dominated by small and medium enterprises, striking among the large companies are Finmeccanica, Eni and Enel, partially controlled by the Ministry of the Economy and Finance. What are the links between politics and the choices of these companies? Have the changes in the political colour of the governments modified the entrepreneurial policies? Starting from the partial privatisation of these large companies, the book seeks to trace the thread linking politics and economics.
Azienda Ospedaliero-Universitaria Meyer. Relazione Clinico-Scientifica 2007-2008-2009
Authors: Sirianni Luigi , Prokopova Zuzana , Majer Katalin
Published: January 2020

The clinical-scientific report 2007-2009 of the Meyer Hospital is the annotated description of the activities stemming from the two elements that make up the 'mission' of the structure: health care and research. It has been structured in such a way that the integration between these two functions emerges as an essential element for the pursuit of hospital excellence.
For those working in the hospital the work undoubtedly represents a useful stimulus for meditation and self-assessment regarding the activities performed; at the same time it also offers an ulterior tool for making the Meyer better known beyond the hospital itself.
Bioinformatics of genome evolution: from ancestral to modern metabolism
Authors: Fondi Marco
Published: January 2020

Bioinformatics, that is the interdisciplinary field that blends computer science and biostatistics with biological and biomedical sciences, is expected to gain a central role in next feature. Indeed, it has now affected several fields of biology, providing crucial hints for the understanding of biological systems and also allowing a
more accurate design of wet lab experiments.
In this work, the analysis of sequence data has be used in different fields, such as evolution (e.g. the assembly and evolution of metabolism), infections control (e.g. the horizontal flow of antibiotic resistance), ecology (bacterial bioremediation).
La filosofia di R. Carnap tra empirismo e trascendentalismo
Authors: Sandrini Maria Grazia
Published: January 2020

This book addresses the development of the thought of Carnap, from his adherence to early Neopositivism through to his more mature reflections, identified here in the essay Empiricism, Semantics and Ontology. The idea is to identify, within his studies on logic, semantics and inductive logic, the philosophical implications that underpin them, and the conflictual tensions characterising the different phases of Carnap's thought.
The appendix proposes Ernesto Palombi's translation of Carnap's article Über Protokollsätze, not previously translated into Italian, complete with meticulous commentary. The article represents a historically important moment, in terms both of the development of Carnap's thought and of the epistemological debate in general.
Rieducazione del piede
Authors: Martinelli Elena
Published: January 2020

The foot is physiologically flat until the age of 4 before gradually transforming into a helicoidal structure with variable step; at the age of 5-6 the vertebral curves stabilize and this happens thanks to the extero-proprioceptive maturation of the foot. Having reached the age of 8-9, many children display defects, amongst the most common: pronation of the rearfoot, flat feet and high-arched feet. This monograph describes the biomechanical and psychomotor study at the basis of static and dynamic distortions in posture and the problems caused by the foot's contact and impact with the ground. It illustrates the contribution of Applied Human Movement Sciences for obtaining fundamental and long-term results in terms of prevention, postural rebalancing and re-education during the developmental, adult and elderly stages of life.
AMAtI (Archivio Multimendiale Attori Italiani)
Authors: Ferrone Siro
Published: January 2020

The Archivio Multimediale degli Attori Italiani (AMAtI) is an on-line computerized archive devoted to the Italian actors, dancers and singers who have practised the profession from the fifteenth to the twenty-first century.
For every actor AMAtI offers a complete original and up-to-date profile, bibliography, list of sources, and a detailed selection of data on his/her career and single performances. Documents, images and multi-media material (video and audio), linked to the collected information, can be viewed in order to provide a more in-depth rundown on each actor. It is also possible to research single performances independently, how characters have been interpreted over time, as well as theatre companies and historical theatres.
Differenziali geografici di sviluppo
Authors: Dini Francesco
Published: January 2020

Geographical differentials of development derive from regional specializations. As classical political economics advised, they are what actively or passively create, and each one with more or less intensity, inter-regional commerce and the nations' different capacities to produce wealth. It is not only through categories of the economy that this capacity can be interpreted: equally as salient factors are the eco-system conditions, cultures and the state formation process. But it is true that the market for a long time has been the form of organization of human behaviour aimed at creating surplus within which this capacity is expressed, distinctly takes shape and gradually builds different pictures from that, since the second half of the twentieth century, usually defined as «economic development». The different capacity of places to produce wealth, in the same way as regional specializations, is indeed subject to endless evolution; the process is long term, very long term, and is characterized by clear but changing geographical regularities, within which moments of accelerated change can yet also be seen. By observing it from a geographical point of view, this work tries to fit the pieces back together, starting from the advent of so-called «capitalism» and going onto look at the logic and rules of the current configurations.
Sull'immagine sonora della città
Authors: Radicchi Antonella
Published: January 2020

The dissertation deals with the contemporary city soundscape and fits into the disciplinary field of sensuous urbanism, soundscape studies and emotional geography. The key term, soundscape, is to be understood as all the sounds that surround us, as a perceptual theme, that is, object of a subject's perception, in its sense of 'landscape' including the metaphorical meaning of an emotional or mnemonic emotional soundscape. The dissertation is structured in two parts: the first and second chapters define the disciplinary spheres of sensory urbanism and soundscape studies, while the third and fourth chapters explore the forms that classical sound environment analysis and planning tools take on within the aforesaid disciplinary fields. Finally, the conclusions give a methodological indication aimed at favouring the integration of soundscape studies within the town planning discipline, and propose «tender sound map» and «sound niche» operating tools to help achieve the goal of planning the contemporary city's physical and sound spaces at the same time.