bluuebunny/crossref_metadata_2025 huggingface dataset:
Human-machine interaction in gait analysis – Review Article
Authors: Radhika Rathi  , Swapna Jawade
Published: November 2022

Background: During locomotion, a gait is a pattern of limb movement. The numerous ways in which a human can move, either naturally or as a result of specific training, are referred to as human gaits. A person's gait is their walking pattern. Walking requires muscle coordination and balance to push the body forward in a rhythm known as the stride. An irregular gait could be caused by a number of factors.Degenerative disease (such as arthritis), stroke, any neurologic ailment, and an inner ear issue are all common causes. Gait analysis is the systematic study of animal locomotion, specifically human motion, employing observers' eyes and brains, as well as apparatus for monitoring body movements, body mechanics, and muscle activation.However, fewer exoskeleton gait planning strategies, such as stride length or step breadth, can suit the demands of patients in real time.
Effects Of Soft Tissue Mobilisation Versus Therapeutic Ultrasound For Patients With Neck Pain- A Randomised Clinical Trial
Authors: Mohini Sunil Gadge  , Swapna Kamble
Published: November 2022

Neck and arm pain is common in the general population.1,2 Individuals with neck and upper extremity symptoms demonstrate greater levels of disability than do individuals with neck pain alone.3 While individuals with cervical radiculopathy often report neck pain, they most frequently seek treatment due to arm pain.3–5 Individuals with whiplash associated disorders who demonstrate signs of irritation of the brachial plexus and subsequent neck and arm pain reported more severe symptoms and achieved worse outcomes than those without brachial plexus irritation.6 Some authors have suggested that patients with neck and arm pain should be treated more expeditiously in order to avoid the further negative impact on mental health status associated with chronic symptoms.
Artificial Intelligence in Stroke – A Review
Authors: Anushri patil  , Shubhangi patil
Published: November 2022

Artificial intelligence is a computer science discipline that can analyse complex medical information. Almost every field of medicine has looked at the capabilities of artificial intelligence systems. Although artificial neural network were the most widely employed logical tool, other artificial intelligent approaches such as transformational computation and hybrid intelligent systems were also applied in a variety of clinical settings. Stroke is a cerebrovascular condition distinguished by the sudden onset of symptoms and scientific findings. Stroke is a main reason of death and morbidity in the world. It can be either ischemic or haemorrhagic, with the former caused by an in-place thrombus or a far-off embolus. The influence of gender on acute ischemic stroke presentation, severity, aetiology, and outcome is becoming more widely recognised. Seizures, conversion illness, migraine headache, and are the most common state that can copy a stroke.
Comparıson Of Lower And Upper Extremıty Y Balance Test Scores Of Some Team And Indıvıdual Adolescent Athletes
Authors: Fatih ERİŞ  , Ergün ÇAKIR  , İbrahim ÇAVUŞOĞLU  , Nida AKYÜREK  , Furkan HAYKIR
Published: November 2022

The aim of this study is to determine the relationships between the Y Balance Test (YBT) upper and lower extremity balance scores of judo, taekwondo, basketball and volleyball players. A total of 46 athletes, including judo (12), taekwondo (10), basketball (10) and volleyball (12), participated in the study. Participants were evaluated with lower extremity Y balance test (LE YBT) and upper extremity Y balance test (UE YBT). The collected data were analyzed with the SPSS 22 program using an independent t test. As a result of the analyzes, it was seen that all of the upper extremity Y Balance Test and Arm length data of taekwondo, judo, basketball and volleyball players were statistically significant according to the branches, and all the lower extremity Y Balance Test and Chimney length data were statistically significant according to the branches P<0,01. As a result, It can be said that lower extremity Y Balance Test and upper extremity Y Balance Test values of basketball and volleyball players, where limb length is at the forefront, are better than judo and taekwondo branches, which are individual double combat sports. This result can be attributed to the limitation of physical structure due to the fact that judo and taekwondo branches are welterweight sports and limitation of the physical activity, and the physical capacity of basketball and volleyball sports to create an advantage in the competition.
THE EFFECTS OF RECREATIONAL ACTIVITIES ON JOB SATISFACTION IN HEALTHCARE PROFESSIONALS
Authors: Abdurrahman Yunus SARIYILDIZ  , Yener AKSOY  , Gülfer AKÇA
Published: November 2022

In this study, it was aimed to investigate the effect of recreational activities on the job satisfaction of health workers. Recreational activities are defined as activities that will relieve physical fatigue of individuals and give them a new strength. Job satisfaction, which is defined as the satisfaction that employees get from their job and the positive impressions they get as a result of evaluating their work, also affects the physical and mental health of employees. Providing sufficient level of job satisfaction and motivation in health services is extremely important for the output of the services. This research was carried out with the participation of 492 people, 234 of whom are women and 258 of whom are actively working in health institutions. In the study, the findings regarding the level of the Job Satisfaction Style Scale sub-dimensions according to whether or not to participate in recreational activities, gender, cigarette use, alcohol use, and monthly income were evaluated in the light of statistical data. It has been determined that the internal job satisfaction factor of the Job Satisfaction Scale differs significantly in terms of medium and high monthly income. There was a significant difference in all factors of the Job Satisfaction scale in terms of the variable of being a smoker. It has been determined that health professionals who use alcohol and participate in recreational activities have higher job satisfaction styles in all factors than health professionals who do not drink and participate in recreational activitie.
Effect of Aerobıc Traınıng Program on Anaerobıc Strength, Balance and Speed Performance in Smokers and Non-Smokers
Authors: Seda AY  , Zarife PANCAR
Published: November 2022

This study was carried out to examine the effect of aerobic training program applied to smokers and non-smokers on anaerobic power, balance and speed performances. For this purpose, a total of 30 male volunteers between the ages of 18-26 were included. A total of 30 healthy male volunteers participated. These individuals were selected from those who attended the aptitude test preparation courses in Gaziantep. According to this analysis, those who were addicted to cigarettes were determined as the smokers group (n: 15), and those who had never smoked were determined as the non-smokers group (n: 15). A two-hour aerobic training program, three days a week, was applied to both groups for eight weeks. Before the training and after the end of the course, repeated anaerobic sprint test, flamingo balance test and 30 meters sprint test were applied. As a result of the findings, in the analysis of the difference between the pre-test and post-test of the smoking and non-smoking groups, there was no statistical significance in the values of the smoking group (p>0.05); In the speed and raster tests of the non-smoker group, a significant difference was found in favor of the post-test, and between the groups in favor of the non-smoker group (p<0.05). As a result, we can say that the eight-week aerobic training program applied to smokers and non-smokers positively changes and improves the balance and speed levels of non-smokers.
Applied remote sensing technique, and GIS to choose suitable Geopark in south east Iraq
Authors: Masar Mahmood Khalf AL-Saedi  , Sahar T. Almulla  , Riaed S. Jassem
Published: November 2022

Sentinel satellite images are enhanced using Erdas-2014 and analyzed by GIS techniques to distinguish the main geological features in the study area. The enhancement process and correct satellite image with Topography, Geomorphology, and Lithology characterize for landscape classify. GIS method environmental, geological, hydrological, and topographic analysis .to identified and assess the suitable location of Geopark in the eastern masian area. This study shows the east misan area has many suitable sites that can be developed as Geopark. By GIS method can choose the suitable Geopark that achieves the basic requirements set by UNESCO for the establishment of Geopark. It includes The existence of wildlife or watery Presence of geological, geophysical, or hydrological factors Hydrogeology is of importance in the region, and high Geodiversity, the area is of importance to ecotourism, The presence of archaeological sites in the region.
OPEN CHOLECYSTECTOMY UNDER THORACIC ANESTHESIA IN A PATIENT WHO HAS CHRONIC OPSTRACTIVE PULMONARY DISEASE WITH HEART FAILURE AND DEVELOPED RESPIRATORY DISTRESS-A CASE REPORT
Authors: Ali M. Hasan Altaiey
Published: November 2022

For decades, the management of symptomatic cholelithiasis in high surgical risk patients has remained contentious. Cholecystectomy has become firmly established as a procedure of choice in the management of symptomatic cholelithiasis. The procedure usually necessitates general anesthesia and endotracheal intubation to prevent aspiration and respiratory embarrassment secondary to the induction of pneumoperitoneum. Open cholecystectomy (OC) usually necessitates general anesthesia and endotracheal intubation to prevent aspiration and respiratory embarrassment. We report our preliminary experience with open cholecystectomy using thoracic anesthesia in patients with cardiac failure and with previous history of smoking. A 78-year-old mal (weight 81 kg, height 176 cm) with abdominal pain applied to the emergency department. After general surgery and infectious disease consultations, he was admitted to the intensive care unit because of high infection parameters and general condition disorder. He had a history of frequent pain at the right hypochondriac region with ultrasonography documented calculi in the gallbladder for two years and heart failure. With the patient at the right lateral decubitus position, EA was performed with a 18-G thoracic catheter inserted 4cm towards the cephalad-direction from T7/T8 successfully. After completion of the surgical procedure, the thoracic catheter was removed, and the patient was shifted to the post-anesthesia care unit (PACU) for further observation. The patient remained hemodynamically stable and comfortable during the 1 hour at PACU. In this case report, we wanted to demonstrate the management of an emergency case with epidemic anesthesia, with a general condition of poor heart failure and septic shock.
Spectrophotometric Determination of Lanthanum (III) With Bromopyrogallol Red And Cetylpridinium Chloride -Applications in Natural Waters and Urine
Authors: Ahmad I. Saber  , Salim A. Mohammed
Published: November 2022

A highly sensitive spectrophotometric procedure for the estimation of lanthanum in aqueous medium has been established. The method was involved the reaction of lanthanum with bromopyrogallol as chelating agent in the presence of cetylpyridinium chloride at pH4.61 to produce a soluble blue colour ternary complex exhibited maximum absorption at 661nm. The method adheres to Beer's low over the concentration range 0.125 –5.0 μg/ml with coefficient determination (r2= 0.9987). The molar absorptivity(ℇ) of the ternary complex (La(III)-BPR-CPC) is 5.39x104 M-1cm-1 which corresponds to Sandell's sensitivity index of 0.00258 μg.cm-2. The stoichiometric composition of the ternary complex was estimated and found to be (1:2:4) (La:BPR:CPC), respectively. The values of detection limit (DL) and quantitation limit (QL) were calculated and found to be 0.0630 and 0.0817 μg.ml-1, respectively. A recovery% was found in the range 95.3% to 103.5%, while the precision (RSD) was estimated in the range 0.126 to 1.705. The proposed procedure has been applied successfully for the determination of lanthanum in natural waters and urine sample.
Molecular Detection of Fungi from Fish Lakes in Wasit Province
Authors: Hawraa. F. H. Al-abedi
Published: November 2022

This study will look for the fungus Saprolegnia parasitica from fish in several lakes in the Wasit Province that are associated with fish farming (carp). Sixty samples were collected from several organs, including the gills, skin, and eyes. Which bears the following signs (skin blisters, gills that have turned dark gray from necrosis, and a blow to the eyes led) were collected from lakes in the Wasit Province during the period (October 2021- December 2021). It might take a lot of time and effort to isolate and identify fungi using traditional procedures. The fish parasite Saprolegnia parasitica may be identified using DNA-based fungal detection techniques (carp). According to the results of this PCR study, fish do not harbor this fungus. As a result, it manifests as deficiencies. It therefore shows itself as inadequacies. Poor management, including a poor feed, insufficient oxygen application, and unclean water, were to blame for the dead fish.
Assessment of Knowledge, Attitudes and Practices of Health-Care Providers about Biomedical Waste Management in Primary Health Centers in Erbil City
Authors: Mooayad A, Rasheed  , Haitham E, Banaa
Published: November 2022

Medical waste is infectious, contain toxic chemicals and pose contamination risks to both people and also the environment in primary health care centers. In the present study, we assessed the knowledge, attitude and practices of health care providers about biomedical waste management in primary health care centers PHCC in Erbil district center, Kurdistan Iraq. Using a self-administered questionnaire, we collected data on biomedical waste management from samples of health care providers (HCP) in 25 health centers in the Erbil district center. Based on results, total knowledge, and attitude and practice scores on a 34 questions was prepared related to Knowledge, attitude and practice. Total 687 HCP participated in study and largest proportion of the sample (40.9%) were aged 41-50 years, more than half (58.4%) were females, nurses constituted 41.5% of the sample, 39.9% were diploma certificate holders, The majority of the sample had more than 10 years of experience, but only 10.8% 74 of them had received training about biomedical waste management. Almost all the participants had no strong knowledge about biomedical waste (BMW) management, and very little (less than 10%) had moderate knowledge. More than 90% of the sample had no information about the weakest and strong microbes resistant to antiseptics, the majority 525 (76.4) have little knowledge about importance to taking the vaccination hepatitis B and C to prevent from BMW hazardous, the majority (93.3%) of the participants believe that safe disposal of BMW is extremely important to prevent infection transmission, more than two thirds (69.9%) of the participants always dispose sharps in puncture proof container. Conducting of appropriate training on how to dealing with biomedical waste is essential to develop safe practices among HCP.
Seroprevalence and newly isolated strains of LT-Ag gene (MMGHA2 and MM GHA5) of BK Polyomavirus in A Sample of Iraqi renal transplant recipients
Authors: Ghufran Hammoodi Abed  , Wisam Mahdi Abbas  , Asmaa Baqer Salem  , Ahmed Sattar Abood
Published: November 2022

Background: BK virus (BKV) opportunistic viral infection causes nephropathy and allograft loss in renal transplant recipients (RTRs).Aims: Investigating BKV seropositivity, viremia rate and renal function were the primary goals of this study, in addition to the molecular study of the Iraqi BKV strains (LT antigen gene).Settings and Design: Case-control study.material and methods: Serum and plasma specimens were collected from 106 RTR and 100 non-RTR. Serum samples were analyzed for anti-BK IgG antibodies by BK-IgG ELISA kit. Plasma samples were used for detection of large tumor (LT-Ag) gene region of BKV by RT-PCR technique and then sequenced by Sanger's method.Statistical analysis: frequencies, percentages, and Chi square-test by SPSS v.28Results: The Study showed that 114 (55.3%) have a positive result for BK-IgG, so there was no significant difference between seropositivity of BKV IgG antibody among the studied groups, p =0.191. On the other hand, a total of 206 subjects, 31 (15.0%) had positive viremia and 175 (85.0%) were negative. Renal function showed highly significant differences (p ≤0.000) between seropositive and negative RTR patients. 2 sequences of Iraqi local strains were deposited in the GenBank with the accession numbers LC718551.1 and LC718552.1Conclusions: The viremic state of BKV in RTR has similarly no impact on renal function. While the highly significant association between seropositivity of BK-IgG with high levels of serum creatinine. New strains of BKV were found in the Iraqi RTR patients with 98% similarity with the reference gene.
THE EFFECT OF USING DIFFERENT LEVELS OF CINNAMON OIL AND GINGER OIL ON SOME QUALITY, PHYSICAL CHARACTERISTICS OF LOCAL GOOSE MEAT STORED BY FREEZING FOR DIFFERENT PERIOD
Authors: Najla Danyar Abdl Wahab ALrdwany  , Adnan Shakor Ahmed Al-Perkhdri
Published: November 2022

This study was conducted on 10/12/2021 until 15/11/2021 in the Graduate Studies Laboratory of the College of Agriculture, Kirkuk University / Department of Animal Production. In order to study the effect of using medicinal plant oils on some physical characteristics of thigh and breast meat for local frozen almonds for different periods at a temperature of -18°C, the meat was minced separately from the thigh and the breast, and the meat was mixed and naturalized. Then it was divided into five treatments, the first treatment (1) was considered the control treatment, as it was not treated with any additives, while cinnamon oil was added at a concentration of (0.25 ml ̸ kg of meat) to the second treatment (T2), and cinnamon oil was added at a concentration of (0.5 ml ̸ kg of meat) ) to the third treatment (T3), adding ginger oil at a concentration (0.25 ml/kg of meat) to the fourth treatment (T4), and adding ginger oil at a concentration (0.5 ml̸ kg of meat) to the fifth treatment (T5). And three replicates for each of the thigh and chest for each period, and were stored by freezing at a temperature of (-18) ° C for periods of 1, 15 and 30 days until physical examinations were performed. The study reached the following results: The treatment of adding cinnamon oil and ginger oil recorded the lowest percentage of loss during thawing and loss during cooking, with an improvement in the ability of meat to carry water when stored in freezing . As for the interaction between treatments and the effect of storage period and treatment effect, we note that there are significant (P<0.05) differences in all study treatments compared with the control treatment. As for the effect of freezing storage periods, the results were: Increasing the storage period led to an increase in the percentage of loss during thawing and loss during cooking and a significant decrease in water carrying capacity.
Assessment of serum alkaline phosphatase and calcium levels during bone fracture healing in dogs stabilized with a bone plate after being treated with an amniotic membrane loaded with platelet rich plasma
Authors: Ali A. Ghadban  , Bassim K. Khashjoori
Published: November 2022

Background/aim: The goal of the present study was to investigate the effects of an acellular amniotic membrane loaded with autologous platelet-rich plasma on bone healing biochemically by measuring serum factors including calcium and alkalinity in a dog model. Materials and methods: Fifteen dogs were used in the current study. The animals were divided into three groups of five dogs each. A transverse osteotomy was induced in the midshaft of the left tibia of all animals. The first group was treated with acellular amniotic membrane only by wrapping it around the fracture site. The second group was given acellular amniotic membrane and platelet-rich plasma to treat them, while the third group (the control) was left alone and not treatedWhole blood was drawn from all groups on the 0th day prior to surgery as well as on the 14th, 28th, 42nd, and 56th days following surgery. Physiological data was then reported. in order to estimate calcium and alkaline phosphatase at various phases of fracture healing. Results: the results of the present study illustrated that the serum alkaline phosphate and calcium levels increased (p≤0.01) on days 14 and 28, followed by a decreasing trend after day 28 to day 56. And their levels were higher in group AM+PRP than in other groups (39.4 ± 1.21, 15.79±0.66 respectively). When compared to the control and AM groups, the rate of formation of new bone tissue in Group AM+PRP was the fastest. It was concluded that serum alkaline phosphatase and calcium were found to be helpful biochemical indicators for evaluating bone development and contributed to proving the superiority of using the amniotic membrane loaded with platelet-rich plasma in promoting bone healing. These biochemical parameters, in conjunction with clinical and radiographic examinations, provide reliable information about the degree of bone healing.
Synthesis and characterization of some new Indazolone and Carbohydrazide derivatives from azachalcones
Authors: Marwa T. Mhmood  , Muneera Y. Roof
Published: November 2022

Pyridine-4-carboxaldehyde can be used for the synthesis 1-aryl-3-(2-pyridyl)-2-propenone(4-azachalcone)(m1-m3) by coupling with acetophenone, 4-methyl acetophenone and 4-amino acetophenone in basic medium. The compounds (m1-m3) converted by Robinson annulation reaction to form the corresponding cyclohexenone derivatives (m4-m6) by coubling with ethyl acetoacetate after mandate reflux. Reaction of cyclohexenone derivatives (m4-m6) with hydrazine hydrate (99%) in presence of some drops glacial acetic acid gives Indazolone derivatives (m7-m8). On the other side, the synthesized cyclohexenone (m4-m6) were treated with hydrazine hydrate (99%) in absolute ethanol to yield carbohydrazide derivatives (m9-m11).The chemical structures of the new compounds (m1-m11) were established on the basis of some physical properties and some spectroscopy methods like, FT-IR, 1HNMR and 13C-NMR spectra. Also, all these reactions followed by thin layer chromatography (TLC) technique.
Synthesis and characterization of some new Indazolone and Carbohydrazide derivatives from azachalcones
Authors: Noor H. Dawood  , Nashwan H.Ali
Published: November 2022

Captopril The sample preparation for captopril using UV-V technology, and the use and advantages of nano-sorbent materials, when applied to the determination and pre-concentration of captopril, were reviewed. In this work, we use spherical silver nanoparticles (Ag NPs) prepared by reacting silver nitrate with citrus aurantium leaf extract to form nanocomposite (CAP_AgNPs), by binding captopril to silver nanoparticles, to obtain a new methodology for captopril identification. Under the chosen experimental conditions, the chain structures (CAP_Ag NPs) were easier to synthesize, stable in the widest pH range and in a regular form. Showed high selectivity and excellent sensitivity to captopril. It was applied for the determination of captopril with overlaid nanomaterial dye. Furthermore, based on electron microscopy (TEM) and X-ray measurements, a mechanism has been proposed. It is assumed that the mechanism of the high selectivity towards captopril arises from the tight binding of the sulfhydryl groups of captopril to the active site of the previously prepared CAP-AgNPs.
The effect of infection with the Entamoeba histolytica on oxidative stress status in Kirkuk hospital patients
Authors: Layth Ali Mohsin  , Sadia Shahab Hamad  , Saleh Muhammad Rahim
Published: November 2022

Entamoeba histolytica is one of the principal intestinal pathogenic parasitic protozoans that cause health issues globally. The purpose of this study is to evaluate how the oxidative stress indicators glutathione (GSH), malondialdehyde (MDA), catalase(CAT), and superoxide dismutase (SOD) are affected by E. histolytica infection. This study, which involved 476 patients of all ages and genders, was conducted between September 2020 and the end of August 2021 to look in to the prevalence of E. histolytica among those who had diarrhea, and tow diagnostic methods were used, including the direct smear method and ELISA technology to detect the parasite in stool samples. 20 blood samples were collected from those infected with the parasite of both sexes, 20 samples from patients suffering from diarrhea symptoms, in addition to 20 samples from healthy individuals as a control group. The results showed that the total percentage of infection with E. histolytica reached to 29.6%. and showed significantly increased the concentration of malondialdehyde (P<0.01) compared to the diarrhea-infected group and the healthy group and the decreased in the activity of glutathione concentration and the activity of catalase enzymes and superoxide dismutase in the infected with the parasite significantly (p<0.01) compared to the diarrhea-infected group and the healthy group.It is concluded from the results of the current study that infection by E. histolytica induced oxidative stress status of the infected people, which may have different health consequences.
Mitochondrial DNA (Hypervariable region II) diversity from Basrah population
Authors: Bassim Muften Ohied  , Adnan Issa Al-Badran
Published: November 2022

Mitochondrial DNA hypervariable regions II of control region were sequenced from 139 random healthy unrelated individuals ethnic of Iraqi population in Basrah city. The aim of this study was to detect and classify the mtDNA haplotypes into mtDNA haplogroups will be better in applications of the forensic genetics and will determine the history of the Iraqi Population The variation in sequence within the D-loop control region was analyzed for the haplogroups composition which displayed a high haplogroups frequency. H, J, U, B, N and R (25%, 12%,12%, 7%, 5% and 5%, respectively, Moderate Haplogroups Frequency L, T and W was (3%) HV, I, X and M (1%), and low haplogroups frequency in pre-HV (0.7%). This study Reported absence of haplogroups V, P, Y, O, Z, Q, G, E and C.
An Evaluation of Factors Affecting Family Business Succession for Smart Human Resource Management
Authors: Sunil Mishra  , Nasa Dhanraj  , M.Seethamahalakshmi  , P.Venkaiah Babu  , Rupa Zabulal Gupta  , Rashmi Mishra
Published: November 2022

Family size, ties to the family, heir preparedness level, planning and management activities, legal counsel, and human resources are some of the internal or controllable aspects that affect how a family business transfers. To evaluate the ease of generational change and the effect of each variable set on the success of the family business in the future, a complete survey of second- and third-generation family business owners/managers was done. A family business's management and treatment of its employees may be impacted by early family influences. This special issue investigates family theory in order to comprehend how families affect human resource management in family firms and how human resource management affects the important outcomes of family enterprises. It implies that careful succession planning is frequently employed as a fruitful experiment for smooth transitions. The goal of the study is to conduct a more thorough analysis of the family business succession process and to pinpoint the elements that support smooth transitions and productive outcomes.
PREGNANCY-RELATED IRON DEFICIENCY ANEMIA AND ITS ASSOCIATION WITH HBA1C
Authors: Muhammad Wasif Saleem  , Shazia Hashmat  , Huma Salahuddin  , Kevin Joseph Jerome Borges  , Inayatullah  , Syed Nudrat Nawaid Shah
Published: November 2022

BACKGROUND: Iron deficiency anemia is most common nutritional deficiency in pregnant women due to increased iron turnover and additional requirement by fetus. Glycemic index is popularly measured by assessing glycated proteins. HbA1c is affected by several factors including pregnancy.OBJECTIVE: The aim of this study is to assess the relationship between iron deficiency anemia in pregnant women and glycated protein (HbA1c).PATIENTS AND METHODS: It is a prospective study conducted at a tertiary care hospital between the duration of April 2019 to June 2019. Total of 40 normal females were taken as control group, while 42 pregnant non – diabetic iron deficient patients.RESULTS: Both groups included females of reproductive age. All parameters including hemoglobin, serum iron, serum total iron – binding capacity (TIBC), serum transferrin saturation and serum ferritin showed statistically significant between two groups (p <0.001). HbA1c also showed statically significant difference (p = 0.021).CONSLUSION: Study showed strong correlation between iron deficiency anemia and glycated proteins as it is increased as iron deficiency develops. So it may give false increase in levels in evaluation of glycemic index.
Assessment of Depressionn, Anxiety and Stresss among a Samplee of patients with Chronic HepatitissB in Gastroenterology and Hepatology Center/ AL-Najaf Province
Authors: Hanan N. Najaf  , Dheyaa J. Kadhim  , Helen F. Marzooq
Published: November 2022

Objective: Hepatitis B has recently been identified as the primary cause of cirrhosis, chronic hepatitis, and hepatocellularr cancer (HCC) (1). stress, depression, anxiety, and other psychological problems accompanied with decay in social and work functionality along may occur in patients with CHB (2). The study's objective was to assess the prevalence and severity of depression, anxiety, and stress in a sampling of chronic hepatitis B patients at the gastroenterology and hepatology center in the Iraqi province of Al-Najaf.Subjects and methodd: ̏ The Gastroenterology and Hepatology Center/Al-Sader Medical City/Najaf treated 104 patients with chronic viral hepatitis B who had already been diagnosed with the disease between November 2018 and May 2019. 100 people who appeared to be in good health were also added as a control group. To evaluate mental health, the Depression, Anxiety, Stress scale (DASS-21) in Arabic was employed.Results: Depression, anxiety and stress which associated in patients with hepatitis B were significantly affected on quality of life of those patients where the prevalence rate of depression, anxiety and stress was significantly high in compared with healthy control group and within extremely severe stage.Conclusion: In conclusion, chronic hepatitis B patients have a higher significantly prevalence rate and level of severity of depression, anxiety and stress which consequently greatly affected on quality of life in comparison to healthy control individuals at the province of AL-gastroenterology Najaf's and hepatology center .
The Antioxidant Impact of Supplementing High and Low doses of Ashwagandha Extract in Chronic Pancreatitis Induced Experimentally
Authors: Badria Al-Harbi  , Rasha H. Hussein  , Reem Al-azragi
Published: November 2022

The pancreas is part of the gastrointestinal system that lies in the upper abdomen behind the stomach. It is a mixed endocrine/exocrine gland enveloped by a thin layer of connective tissue. Connective tissue septa invade the gland, dividing it into lobules, serving as a support for tissue and providing a pathway for vasculature, nerve fibers, and lymphatic ducts. The pancreas lacks a complete fibrous capsule (Abozaid et al., 2020). The pancreas is composed of exocrine portion which comprises more than 95% of the pancreatic mass and it responsible for makes and secretes digestive enzymes into the intestine and endocrine portion (the islets) which makes and secretes hormones as (insulin, glucagon, somatostatin and pancreatic polypeptide) into the blood to control energy metabolism and storage throughout the body, it includes acinar and duct cells with associated connective tissue, vessels, and nerves.it comprise 1-2% of pancreatic mass Mederos et al (2021).
RESULTS OF THE STUDY OF RESISTANCE TO CLARITHROMYCIN IN PATIENTS WITH HELICOBACTER PYLORI-ASSOCIATED GASTRIC DISEASES IN UZBEKISTAN
Authors: J.A.Ismailova  , A.A.Yusupbekov  , A.A.Abdurahimov
Published: November 2022

The authors studied the resistance of bacteria to clarithromycin in 194 patients with a positive CagA gene of H. pylori-associated stomach diseases. The study is based on the results of molecular genetic research methods and statistical data. According to the study, the studied population was characterized by the presence of three types of gene mutations in the 23S-rRNA gene: 2142 G, 2142C and 2143 G. Wild type Wt type H. pylori was detected in 58.8% of cases.
Skill and Simulation Lab in Dentistry – A Futuristic Era
Authors: Rachita G. Mustilwar  , Ira Gupta  , Harsha Hardiya  , Fazil Arshad Nasyam  , Anshu Gupta  , Aleta M Shyam
Published: November 2022

Simulation is a technique where the situation or a process is imitated. This process makes one to pretend the scenario. Aviation industry is one of the oldest industry which uses simulation technique to simulate the aviation technique. The main aim of having simulation lab is to make students acquire psychomotor skills before they actually treat the patients. Presently the National Medical Council of India has made it mandatory to have a skill lab but desirable to have a simulated mannequin for the training of medical students before actually treating the patients. Various advantages and disadvantages are appreciated in simulation technique. It is not very far that Dental council of India may make compulsory training of certain simulated modules in dentistry before treating the patient. Simulation lab in the pandemic like COVID has really helped people to undergo extensive training before treating patients, especially one who were catering the COVID ward or intensive care units. The simulation in dentistry is not a very old technique, certain technique are already in practice, but this article tries to highlight the necessity and gray areas where simulation can be improved for the benefit of students to learn and for the benefit of patients in view of safety.
SYNTHESIS AND STUDY OF N,N1 - HEXAMETHYLENE BIS- {[(4,41-DIMETHYLDIPHENYL)-AZO-2,21-DIAMINO] UREA} PROPERTIES, APPLICATIONS
Authors: Holboyev Yusufjon Khakimovich  , Abdurakhmanov Ulugbek Kurganbaevich  , Makhsumov Abdukhamid Gafurovich  , Valeeva Nailya Gennadievna
Published: November 2022

The proposed article relates to organic chemical synthesis and the study of bis-azourea compounds, the chemical properties of new N,N1 derivatives - hexamethylene bis-[(4,41-dimethyldiphenyl)-azo-2,21-diamino) ureas]. The interaction of [(4,41-dimethyldiphenyl)-azo-2,21-diamino)-urea] with hexamethylene diisocyanate gave derivatives N,N1 - hexamethylene bis-[(4,41-dimethyldiphenyl)-azo-2,21-diamino) ureas]. The structure of N,N1 - hexamethylene bis-[(4,41-dimethyldiphenyl)-azo-2,21-diamino)urea] was established by elemental analysis, IR and PMR spectroscopy. Reactivity of NH reaction centers N,N1 - hexamethylene bis-[(4,41-dimethyldiphenyl)-azo-2,21-diamino) urea] is studied by the reactions: N,N1-dinitrosation, N,N1-dimetallation, N,N1 -dialkylation, N,N1-dichlorination. Comparative tests show that the tested derivative of the N,N1 compound - hexamethylene bis-[(4,41-dimethyldiphenyl)-azo-2,21-diamino)urea] showed a higher growth-promoting activity.
Quantification of an Anti-Rheumatic Agent: Upadacitinib in Biological Fluid (Plasma) By LC- MS/MS
Authors: Yamarthi Venkateswara rao  , Jithendra Chimakurthy
Published: November 2022

Aim: Upadacitinib is a Janus kinase/signal transducers and activators of transcription (JAKs) of cytoplasmic tyrosine kinase that has been proven to be effective in treating inflammatory conditions and various immunological diseases/disorders, including rheumatoid arthritis. Tofacitinib and ruxolitinib, which are members of this drug's first generation, did not affect JAK1/JAK3 or JAK1/JAK2 receptors specifically due to a lack of subtype selectivity. As far as we are aware, there is currently no method for the accurate quantification of the anti-rheumatic drug upadacitinib in biological fluid.Material and Materials: To detect upadacitinib in biological fluid, an unique and reliable LC-MS/MS technique must be developed. Using a symmetric C18 column (150 x 4.6 mm, 3.5 m) and isocratic elution with acetonitrile: water (50:50) as the mobile phase, we created a unique bioanalytical approach here. Formic acid was used to bring the mobile phase's pH down to 4.0, and the flow rate was 1 ml/min. The retention time of the medication was discovered to be 3.12 min, and the total run time was set to 7 min.Results: With a correlation coefficient (r2) of 0.999, the upadacitinib linearity curve was established at concentrations ranging from 12.5 ng/ml to 100 ng/ml. The theoretical plates, resolution, and tailing factor are system suitability parameters found to be within the acceptable criteria. The recovery studies indicated that the developed method can extract the acceptable % amount of drug 100.3%. The matrix effect study indicates there is no effect of matrix on recovery, the result shown as 104.20% and also other validation parameters like precision, LOD, LOQ are within the acceptable criteria.Conclusion: The created techniques enable a precise, delicate, and consistent analytical process for the estimation of Upadacitinib in biological matrix. The stability studies indicate the drug is stable in different accelerated stability study conditions the results are within limits.
The effect of an intermediate dose of Heparin solution in the Prevention of Central Venous Catheter occlusion on ICU admitted patients: A randomized Controlled Trial
Authors: Asieh Yahyaie  , Ahmad Bagheri Moghaddam  , Alireza Sedaghat  , Majid Khadem-Rezaiyan  , Somaye Akbari  , Jafar Motaharinasab
Published: November 2022

Background and aim: Central venous catheters (CVC) are widely used in critical care units. Due to the high prevalence of central venous catheter dysfunction, the cost, and the complications of their replacement, finding the right way to prevent catheter occlusion becomes important. The current study aimed to evaluate the effect of an intermediate dose of heparin solution in the prevention of central venous catheter occlusion in ICU-admitted patients.Method: This randomized controlled trial was performed in the Adult Intensive Care Unit (AICU) of Imam Reza Hospital from 2019 to 2020. In each patient (153 patients), the lines were divided into two categories: active or inactive. Inactive lines in the intervention group (76 patients) were washed every 8 hours with 10 ml of saline solution and then filled with 1.5 ml of heparin solution (at a concentration of 100 units per ml). In the control group (77 patients) only washing with 10 ml of saline solution was performed. The active lines in the intervention group were first washed with 10 ml of saline solution after each use and filled with 1.5 ml of heparin solution if not used immediately. In the control group, only saline washing was performed. Each line was examined once daily during the morning shift to determine whether it was open or closed.Result: In the studied lines in 153 patients admitted to the intensive care unit who were divided into two groups of intervention (heparin) and control (saline), no significant difference was observed in the occlusion of the catheter lines (p>0.05).Conclusion: After 14 days of examination of central venous catheters in patients, the effectiveness of an intermediate dose of heparin in preventing catheter obstruction was not more than the saline solution.
SOME COMMENTS ON THE STUDY OF NAZAR ESHANQUL'S WORK IN LITERARY STUDIES
Authors: KURDOSH KAHRAMONOV
Published: November 2022

The article examines the study of the works of the talented writer Nazar Eshanqul in contemporary Uzbek literary studies and criticism. The author's poetic world, the skill of character creation, the use of various poetic elements - metaphorical image, symbols and symbols, and issues of creative influence are the leading issues in the published studies.
Correlation of Placental Thickness with Gestational Age and Other Fetal Parameters Among Pregnant Women: A prospective cross-sectional study from North India
Authors: Arvind Kumar Jha  , Yogesh Yadav  , Nisha V Kaul  , Ashish Kumar Shukla  , Neelima Agarwal
Published: November 2022

Background: Placental thickness is the lone parameter that can predict gestational age without relying on the foetus. For many years, the last menstrual period (LMP) date has been used to calculate the foetus gestational age; but, as shown by the studies, approximately 56 percent of females can recall the last menstrual period date with absolute precision. This forgetting might not have a big impact on an uncomplicated pregnancy, but in complicated pregnancies, proper foetal gestational age data is vital. In order to determine the relationship between placental thickness and foetal age and other growth parameters, this study was carried out.Methods: Between July 22, 2021, and July 22, 2022, the Department of Anatomy at Santosh Medical College and Hospital in Ghaziabad, Uttar Pradesh, India, worked with the Departments of Radiology and Obstetrics & Gynaecology on this prospective cross-sectional study. The convenient sampling technique was used to enrol the study subjects, and during the first five months of study, 254 ANC subjects with gestational ages between 11 and 20 weeks were included in the study. The pregnant subjects were examined by USG machine for gestational age (GA), and placental thickness (PT). The analysed data were represented as frequency, percentages, mean, median standard deviation (SD), minimum and maximum values.Results: Among enrolled pregnant subjects, the most common placenta positions were anterior (42.6%) and posterior (30.1%). Between the time of enrolment in the study (1.61±0.26 cms), the first follow-up visit (2.62±0.07 cms), and the second follow-up visit (3.35±0.26 cms), the mean placental thickness significantly increased. A very significant association (r=0.746) was found between gestational age and placental thickness in the Pearson correlation analysis of subjects between 31 and 40 weeks of gestation. Similar to this, a very significant correlation (r=0.965) was found between gestational age and foetus gestational weight.Conclusion: In our study during the first, second, and third trimesters of pregnancy, there was a significant linear association between placental thickness, gestational age, and other foetal parameters. Statistics was found to support the relationship.
Maternal and fetal outcome in preterm premature rupture of membrane: A cross sectional study
Authors: Nidhi Patel  , Deepashree Arbune  , N. S. Kshirsagar  , Shital patil
Published: November 2022

Background: The present study was conducted for assessing the maternal and fetal outcome in preterm premature rupture of membrane.Materials & methods: A total of 100 pregnant subjects were enrolled in the present study. Only those subjects were enrolled who were diagnosed with preterm rupture of membrane (PROM). The outcome variables for this study were maternal and fetal outcomes, grouped as favorable and unfavorable (complications). All the results were recorded in Microsoft excel sheet and were analysed by using SPSS software.Results: About 19% of the women showed unfavorable maternal outcomes.79 percent of the subjects were of primigravida. Duration of PROM was less than 12 years in 68 percent of the patients. Out of 19 subjects with maternal complications, sepsis, wound infection and haemorrhage was seen in 10 percent, 5 percent and 4 percent of the patients respectively. Still birth was seen in 7 percent of the patients while need of NICU was seen in 21 percent of the cases.Conclusion: In conclusion, PPROM is associated with a prenatal morbidity and the key to reducing the adverse effects of PPROM is to make a prompt diagnosis, admission and start antibiotic coverage.
Insight to oral health status, knowledge and practices of Saudi Pregnant women
Authors: Khalid Ibrahim Almutlaq  , Rahul N Gaikwad  , Feras Sulaiman Alfreidi  , Nada Asker Alrkabee  , Nujud Ibrahim Almutlaq  , Salman Sadeq Abdo
Published: November 2022

Background: Pregnancy is a time of increased susceptibility in terms of dental health due to typical physiological changes. Pregnant women with better oral health are less likely to experience pregnancy-related dental disease problems.Methodology: This cross-sectional study was conducted at college of dentistry, Qassim university, Qassim province of Saudi Arabia. A piloted tested self-administered questionnaire was used to collect data which was available in Arabic and English languages. Data collection was done through social media platform among pregnant women. Pearson's chi-square test was used to analysehe difference of opinions among different trimester of pregnant women’s.Result: In the present study, 208 pregnant women’s responded to online forms through social media platform, with mean age of participants was 33.10 ±8.11. Significantly, higher number of second trimester woman reported dental problem and majority of them attended private dental clinic. The majority of women’s were dissatisfied about the instruction given by gynecologist for dental care. But surprisingly, significantly higher number of women were aware about the aware about eruption time of baby tooth and harmful effect of bottle-feeding.Conclusion: Saudi women's oral health knowledge and practices need to be improved in order to prevent dental and oral diseases and to motivate them to receive routine dental care in order to ward off additional illness.
To evaluate the incidence of gallbladder content spillage and the factors contributing to it during laparoscopic cholecystectomy
Authors: Salunkhe Paras Vijaykumar  , A Y Kshirsagar  , H B Janugade
Published: November 2022

Aim: To evaluate the incidence of gallbladder content spillage and the factors contributing to it during laparoscopic cholecystectomy.Materials and methods: The research comprises 100 consecutive laparoscopic cholecystectomy patients. The data was collected prospectively in accordance with the proforma, which documented the patient's detailed diagnosis, preoperative physical and ultrasound abdomen findings, intra-operative details such as technique, spillage of stones, cause of spillage, method and port of specimen extraction, duration of surgery, and postoperative events and complications. A one-week, one-month, six-month, and one-year postoperative follow-up was undertaken.Results: In our research, 100 consecutive laparoscopic cholecystectomy procedures were performed. There were 63 female patients and 37 male patients among them. The research group's average age was 49.85±11.58 years. The majority of the patients had several 1 cm movable gallstones. In 88% of patients, the procedure lasted between 30 and 60 minutes. Adhesions of varied degrees were found in 78% of the cases, resulting in a 7% conversion rate. Minimal bleeding was seen in 51% of the instances, significant haemorrhage in 37% of the cases, and no bleeding was observed in 12% of the cases. Gallstone leakage happened in 20% of the instances. In our research, the complication rate for laparoscopic cholecystectomy was 3%; however, the complication rate from spilled gallstones was 1%. At 1, 6, and 12 months of post-operative follow-up, no complaints about the procedure were noted.Conclusion: Leakage of gallstones and bile after routine laparoscopic cholecystectomy is uncommon and usually results in very minor problems. To prevent difficulties after a spill, it is crucial to remove the stones and do a peritoneal toileting.