bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical and morphological characteristics of chronic pelvic pain in patients with hyperproliferative diseases of the genitals
Authors:   SI Dnipropetrovsk Medical Academy, Ministry of Health of Ukraine, Dnipro, Grek L.P. , Dubossarskaya Z.M. ,   SI Dnipropetrovsk Medical Academy, Ministry of Health of Ukraine, Dnipro
Published: March 2022

Chronic pelvic pain is one of the most significant medical and social problems. The high prevalence of concomitant benign genital diseases in women of reproductive age are genial endometriosis, uterine fibroids, endometrial hyperplasia with common clinical manifestations, namely chronic pelvic pain, abnormal uterine bleeding, impaired reproductive function, and a high frequency of cancer pathology of the reproductive organs in young age that require a holistic approach to patient management and comprehensive problem solving. The objective: to investigate the proliferative and inflammatory activity of the glandular and stromal components of the eutopic endometrium (EE), the presence of nerve fibers in it as mechanisms for the formation of СРР in genital endometriosis in combination with other benign hormonedependent diseases of the genitals Materials and methods. The study involved 85 women with chronic pelvic pain due to genial endometriosis, uterine leiomyoma, endometrial hyperplasia, chronic salpingitis and oophoritis in various combinations, and 35 women by the comparison group with similar gynecological pathology without CPP. In order to objectify pain syndrome, a 10-point visual analogue scale (VAS) was used. Echography of the pelvic organs, the thyroid gland (if necessary) was performed by the Toshiba, Nemio17-pro apparatus. In order to study the molecular mechanisms of the development of CPP, the expression of ER, PGR, KI-67, VEGF, COX-2, NF in the eutopic endometrium was determined by immunohistochemistry. Results. The leading painful role in combined gynecological pathology was assigned to diseases in clinical group 1, which had the most pronounced algogenic anatomical and structural features. Formation of CРР is confirmed by the presence of rank correlations between the level of pain syndrome in VAS and immunohistochemistry characteristics with reliable direct connections of average strength with the ER (Spearman’s coefficient of correlation ρ =0.58; p<0.001), with PGR (p=0.42; p=0.021), with Ki-67 (ρ =0.55; p=0.004) and with COX-2 (ρ =0.42; p=0.021). Conclusions. The concept of the pathogenesis of СРР in proliferative genital diseases has been expanded. It is characterized by moderate expression of VEGF, high expression of ER and PGR, Ki-67 and COX-2, with NF in EE; which determines the development of СРР by the criteria being studied, both individually and in combination. Key words: chronic pelvic pain, proliferative diseases of the genitals, morphogenesis markers.
Atypical hemolytic uremic syndrome in the eyes of the obstetrician (Literature review)
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Lakatosh V.P. , Kupchik V.I. ,   Bogomolets National Medical University, Kyiv, Ukraine, Guzhevskaya I.V. ,   Bogomolets National Medical University, Kyiv, Ukraine,, Kostenko O.Yu. ,   Bogomolets National Medical University, Kyiv, Ukraine, Lakatosh P.V. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: March 2022

The article presents an overview of native and foreign publications on atypical hemolytic-uremic syndrome. Modern terminology, classification is presented, questions about the causes and pathogenesis of this pathology are considered. The opinions of experts of obstetric and gynecological communities of the world on questions of clinics, diagnostics and treatment are given. Key words: pregnancy, obstetric atypical hemolytic-uremic syndrome, eculizumab.
Personalization of Staff Training As an Adaptive Technology of the Future
Authors:   Surgut State University, Shirinkina Elena
Published: March 2022

The relevance of the study is due to the fact that adaptability will become a hit of corporate training in the coming years. In this regard, the article defines the conceptual base, presents the prospects for the development of trajectories for personalization of personnel training, evaluates the existing models and presents an analysis of the best practices for personalization of training. The purpose of the study is to present technologies that will provide the necessary and sufficient depth of analytics for building personal learning paths. An individualized path of personnel development is natural when there is a clearly defined system of a closed set of knowledge and skills, because everyone has their own pace of development, a line according to the type of problem acceptance and decision. The extent to which personalization will be associated not with a closed learning situation, but with an open development situation (where there is only a vector, not a format), depends on the company’s ability to use these tools.
Inflation Uncertanty Influence on Corporate Debt Term Structure
Authors:   Lomonosov Moscow State University, Gurov Ilya , Burdin Tikhomir ,   Lomonosov Moscow State University
Published: March 2022

The subject of this study is the long-term financial indebtedness of companies. The purpose of the article is to identify the constraints that inflationary processes impose on the temporary structure of debt financing for capital-intensive companies. During the study, such scientific methods as analysis, synthesis, longitudinal method, as well as methods of quantitative analysis were used. The authors showed that companies take the service life and payback of their assets into account when choosing the time structure of long-term debt, which confirms the hypothesis that the service life of assets and the time structure of financial liabilities are consistent. At the same time, the uncertainty of inflationary expectations in developing countries has a statistically significant negative impact on the ability of companies to attract long-term financing. The limited availability of long-term financing for companies from developing countries leads to the fact that such companies are forced to abandon the implementation of long-term projects with a positive net present value.
Features of Functioning of Special Economic Zones in Russia at the Current Stage of Development: Problems and Prospects
Authors:   Volgograd State University, Buyanova Marina , Kryukova Ekaterina ,   Astrakhan State University
Published: March 2022

The article presents an analysis of the features of the functioning of special economic zones in Russia at the present stage of development. Port special economic zones represented by Murmansk and Ulyanovsk regions, as well as the Khabarovsk Krai were selected as the object of research. The indicated special economic zones are analyzed from the perspective of their similarities and differences in terms of the initial conditions of development, target guidelines, as well as types of economic activities. As a result of the analysis of the indicated economic entities of the Russian Federation, the problems and development prospects of each of them were identified. The directions for improving the functioning of free economic zones (of institutional and economic nature) have been determined, which can be introduced into reality through the interaction of the business sector with public authorities, and, accordingly, resolving the contradictions between their heterogeneous interests within the framework of achieving a common goal – increasing the efficiency of some territories of the abovementioned regions. This circumstance is considered from the point of their compliance with modern challenges and threats that are dictated by new economic realities, but at the same time, open up unique unprecedented opportunities for their exponential development in terms of competitiveness, stability and security.
Principles of Forming the Economic Effect of Typification Design Solutions for Oil and Gas Facilities
Authors:   Tyumen Petroleum Research Center, Kravchenko Alexandr
Published: March 2022

This article opens a series of publications devoted to the problems of evaluating the effectiveness of the use of standard solutions in the oil and gas sector. The maximum effect of increasing the efficiency of production processes can be achieved with the introduction of a complex of new technologies, best practices, approaches and innovations (standardization, unification, effective design solutions, improving production efficiency, multi-level decomposition design, digital technologies, etc.). Both domestic and foreign scientists pay special attention to the theory and methodology of evaluating the effectiveness of enterprises. The publication provides general formulas for calculating economic efficiency, typification coefficients, reduction of the complexity of creating project products using standard solutions and the economic effect of using standard design solutions. The analysis of the innovative development programs of the largest companies of the complex allows us to determine its priority areas: cost reduction, development of new methods of energy extraction, discovery of new methods of equipment design, introduction of digital technologies, improving the efficiency of design solutions, search and implementation of innovative ones. The tasks of introducing innovative technologies and effective design solutions into the production process of oil and gas producing enterprises are solved by improving the methodological base, optimizing design solutions and managing design technology. Examples of effective design solutions are given. The development of standard design allows us to realize the qualitative and economic advantages of replicating effective design solutions, which is expressed in improving the quality of design solutions, reducing costs and timing of design and construction and installation work. Due to the development of typification and the analysis of technical solutions carried out on a constant basis, within the framework of large fuel and energy companies, it becomes possible to build an effective management platform and synthesis of best practices in a single solution. The publication presented to the readers sets out the main directions of obtaining an economic effect from the typification of project solutions, which are important for further understanding of the problems of evaluating the effectiveness of typing and unification.
Dois pesos e duas medidas na sala de aula: análise das redes sociossemânticas de categorização operadas por professores
Authors: Lotta Gabriela , Kirschbaum Charles
Published: March 2022

Resumo Este artigo analisa categorias operadas por burocratas ao classificar tipos de usuários e seus efeitos em distribuição de serviços, observando contextos de alta desigualdade e políticas universais. Para tanto, analisa de que modo professores, como burocratas de nível de rua, implementam a política categorizando diferentes tipos de alunos. Adotamos aqui a lente analítica de esquemas culturais, que considera que indivíduos internalizam associações entre categorias oficiais e sociais (informais). Os dados analisados foram coletados de vinhetas aplicadas com 40 professores da rede municipal de São Paulo. Investigamos o uso de categorias por meio de redes sociossemânticas e semânticas de categorizações e construção de cadeias de encaminhamentos. Os resultados apontam que os professores mobilizam de forma concomitante categorias oficiais e sociais, bem como que a introdução da variável “vulnerabilidade” nos casos abre espaço para introdução de categorias sociais que geram diferentes tipos de tratamento para alunos com comportamentos similares.
Paradoxos na divulgação de salários de servidores em municípios
Authors: Precinotto André , Aquino André Carlos Busanelli de , Dias Lidiane Nazaré da Silva
Published: March 2022

Resumo A folha de pagamento é uma das maiores despesas do município, porém uma das mais difíceis de serem monitoradas. Se a divulgação dos salários de servidores é de interesse público para controle, a divulgação das despesas com pessoal, na forma como previsto em lei, pode não ser suficiente para detectar diversos tipos de irregularidades. Analisamos os paradoxos envolvidos na divulgação de dados da folha de pagamento e as tensões que emergem do posicionamento de diversos interessados na questão. Entrevistamos profissionais de prefeituras, sindicatos, empresas de softwares, tribunais de contas, organizações sociais e jornalistas. Procuramos reunir diversas perspectivas e interesses envolvidos na divulgação de salários e benefícios de servidores como exemplo dos desafios de ampliar a transparência pública. Com abordagem indutiva, apresentamos uma lista não exaustiva de irregularidades que reconhecidamente ocorrem no país e que, por não serem detectadas apenas com os dados divulgados nos portais de transparência, demandam cooperação entre diversos atores de controle.
A instabilidade ministerial importa? Compreendendo a produção legislativa dos ministérios no Brasil
Authors: Ribeiro Pedro Feliú , Poiatti Natália Dus
Published: March 2022

Resumo O que explica a produção legislativa dos ministérios federais no Brasil? O artigo explora a relação entre a instabilidade ministerial e o desempenho dos ministérios mensurado pela quantidade de propostas legislativas produzidas entre 1999 e 2014. Por meio de um modelo de média exponencial com regressores endógenos, argumentamos que a troca de ministros e ministras afeta negativamente a capacidade de produção legislativa das pastas. Ainda assim, o distanciamento ideológico entre os partidos do ministro e o presidente, bem como a expertise legislativa prévia dos ministros, tem impacto mais pronunciado no nível de produção de propostas legislativas dentro da agenda política do governo. Os resultados corroboram a percepção do efeito negativo da instabilidade ministerial na eficiência da concepção e da formulação de políticas públicas, contribuindo para o entendimento da produção legislativa e do desempenho burocrático do presidencialismo brasileiro.
Policy drift in ideologically heterogeneous governments: tax policy in Latin America
Authors: Lazzari Eduardo
Published: March 2022

Abstract The relation between taxation and partisanship is a widely studied topic in Political Science. However, previous works have provided conflicting findings without clarifying which parties are most prone to progressive taxation. These studies also did not consider one distinctive feature of Latin American politics: coalition governments. Using the level of direct tax collection as a proxy for progressive taxation and panel data of Latin American countries since 1990, we investigate how progressive taxes vary across a scale of ideology observed in the executive branch along with the ideological heterogeneity of its coalition. The results show that ideologically heterogeneous governments present a policy drift, as the policies being enacted depart from parties’ original preferences. Homogeneous left-wing governments collect more direct taxes than ideologically heterogeneous coalitions led by governments with the same ideology. The same dynamic is observed with homogeneous right-wing governments, which collect more indirect taxes in ideologically homogeneous coalitions. These results create new paths of research highlighting the need to include the government’s composition in the analysis to understand policy design and the need to unravel the mechanism through which policy drift occurs in ideologically heterogeneous governments.
Performance and outcome of ressucitative thoracotomies in a southern Brazil trauma center: a 7-year retrospective analysis
Authors: HAIDA VITOR MAMORU , YAMASHITA EDUARDO MASSARO , FRANCO GIÓRGIA SOUZA , AMADO WELLIDHA BIANCA ROCHA , ARAKAKI ISABELLA KOHATSU , DAL-BOSCO CAROLINE LOUISE BALCEWICZ , ZWIERZIKOWSKI JAQUELINE ALVES , COLLAÇO IWAN AUGUSTO , CAVASSIN GUILHERME PASQUINI
Published: March 2022

ABSTRACT Objective: the study aims to analyze the performance and outcome of resuscitation thoracotomy (TR) performed in patients victims of penetrating and blunt trauma in a trauma center in southern Brazil during a 7 years period. Methods: retrospective study based on the analysis of medical records of patients undergoing TR, from 2014 to 2020, in the emergency service of the Hospital do Trabalhador, Curitiba - Paraná, Brazil. Results: a total of 46 TR were performed during the study period, of which 89.1% were male. The mean age of patients undergoing TR was 34.1±12.94 years (range 16 and 69 years). Penetrating trauma corresponded to the majority of indications with 80.4%, of these 86.5% victims of gunshot wounds and 13.5% victims of knife wounds. On the other hand, only 19.6% undergoing TR were victims of blunt trauma. Regarding the outcome variables, 84.78% of the patients had declared deaths during the procedure, considered non-responders. 15.22% of patients survived after the procedure. 4.35% of patients undergoing TR were discharged from the hospital, 50% of which were victims of blunt trauma. Conclusion: the data obtained in our study are in accordance with the world literature, reinforcing the need for a continuous effort to perform TR, respecting its indications and limitations in patients victims of severe penetrating or blunt trauma.
Núcleo Interno de Regulação hospitalar: repercussões da implantação nos indicadores dos serviços de saúde
Authors: Feijó Vivian Biazon El Reda , Barreto Maynara Fernanda Carvalho , Tanita Marcos , Balsanelli Alexandre Pazetto , Cunha Isabel Cristina Kowal Olm , Haddad Maria do Carmo Fernandez Lourenço
Published: March 2022

Resumo Objetivo Avaliar os indicadores hospitalares e suas repercussões, antes e após a implantação do Núcleo Interno de Regulação, no número de internações mensais em hospital universitário público. Método Pesquisa avaliativa, do tipo Estudo de Caso desenvolvida em hospital universitário público. Foram mensurados 28 indicadores relacionados à estrutura, produção, produtividade e qualidade, que integram o referencial de Benchmarking interno. Os dados foram analisados por estatística descritiva e regressão múltipla para identificar os fatores independentes e associados ao número de internações mensais com intervalos de confiança de 95%. Resultados A implantação do Núcleo aumentou significativamente (p<0,001) o número de altas, o fator de utilização e índice de renovação dos leitos, internação de urgência, porcentagem de ocupação dos leitos, procedimentos cirúrgicos realizados e média de paciente-dia (p=0,027). Houve redução (p<0,001) no número de atendimentos no pronto socorro médico, obstétrico e ortopédico, nas taxas de infecção hospitalar e de mortalidade infantil, bem como na diminuição média de permanência de 0,81/dia, aproximadamente um dia a menos de internação por paciente, ou um ganho de 40 leitos disponíveis ao mês. Conclusão Embora o número de leitos disponíveis tenha sido menor no período pós-implantação, o intervalo de substituição de leitos reduziu, representando o aumento de mais 40 leitos ao mês devido à diminuição do tempo de permanência dos pacientes na instituição.
Analysis of sales of vertical residential real estate projects in Goiânia and its influencing factors
Authors: Amaral Tatiana Gondim do , Kafuri Roberto Sebba , Oliveira Marcelo Leite , Kafuri Matheus Ramos , Medrano Ronny Marcelo Aliaga
Published: March 2022

Abstract Several topics were analyzed to produce this article, such as Evaluation Engineering, Data Modeling, Data Mining and Big Data. Although the literature on these theories is extensive, there is no record of their simultaneous use in favor of conducting an analysis of the real estate market in a city or region. The present work aims to use these theories to elaborate and implement quantitative criteria which group real estate projects according to their sale speed in order to classify them as high or low demand in the market. Thus, a database was used to develop the proposal, containing the number of units sold from 268 real estate developments in Goiânia with a launch date between January 2016 to December 2019, recorded month by month, generating a total of 4746 entries in the database. Data Mining and Big Data techniques were used to determine the database to perform the research and enable direct comparison between the analyzed enterprises. It was possible to accurately define the greatest market opportunities by studying the characteristics of the number of bedrooms, private square footage, price per square meter, apartment price and location.
Perfil do consumidor de alimentos funcionais: identidade e hábitos de vida
Authors: Safraid Giovana Flores , Portes Cristine Zanquetta , Dantas Roseana Machado , Batista Ângela Giovana
Published: March 2022

Resumo Com a mudança na alimentação dos adultos nas últimas décadas, aumenta o desenvolvimento de doenças crônicas não transmissíveis. Aumentar o consumo de alimentos funcionais, com ações metabólicas benéficas ao organismo, é uma estratégia para proporcionar benefícios à saúde em longo prazo. O objetivo deste trabalho foi identificar os fatores que têm influência na percepção e no consumo de alimentos funcionais por adultos. Neste estudo, dentre os fatores que interferem no consumo de alimentos funcionais identificados, os aspectos socioeconômicos, de saúde e de qualidade dos alimentos se destacaram. No âmbito geral, apesar de controvérsias, os estudos caracterizam os consumidores de alimentos funcionais como mulheres, de boa situação financeira e alto nível de escolaridade, que se preocupam com a saúde de forma global, na medida em que praticam atividades físicas e têm uma alimentação adequada. Ademais, percebe-se que a cultura local tem bastante influência na percepção dos alimentos funcionais. Alguns fatores, como a familiaridade, sejam do produto, seja da alegação funcional, também são importantes para determinar a atitude do consumidor perante esses alimentos. O sabor é o principal atributo sensorial que define o consumo de alimentos funcionais. Os consumidores também tendem a preferir alimentos que são considerados naturais e não processados. Portanto, estudos que relacionem hábitos globais de saúde e o consumo de alimentos funcionais podem ser interessantes para assim nortear as intervenções e a inovação na produção de alimentos nesta área.
Management of bruxism associated with temporomandibular disorder: case report
Authors: OLIVEIRA Marcus Vinícius Andrade , PORTO Marco Aurélio Fonseca , SIMAMOTO JÚNIOR Paulo Cézar , COELHO Uriel Paulo , CABRAL Luana Cardoso
Published: March 2022

ABSTRACT Studies have found the association between episodes of bruxism and the presence of signs and symptoms of temporomandibular disorder (TMD). The aim of the present study was to report the diagnosis and palliative therapy of bruxism associated with TMD. Patient, 23 years old, male gender, presented at dental clinic, complaining of pain in the temporomandibular joint on the left side and alteration of the form of the anterior teeth. During the anamnesis it was documented that this symptom was recurrent and reported the habit of grinding teeth. The clinical examination observed discrepancy between the centric relation and the maximum habitual intercuspation, unsatisfactory protrusive guide, presence of wear facets, clicking and mandibular deviation during mouth opening. The Research Diagnostic Criteria for Temporomandibular Disorders (RDC / TMD) questionnaire was applied to diagnose TMD. By means of specific algorithms this disorder was classified as myofascial pain, disc displacement with reduction and osteoarthritis, all affecting the left side. Thus, it was proposed the assembly of the models in semi-adjustable articulator for occlusal mapping and waxing diagnosis, then the occlusal adjustment by selective wear and material addition was executed. After this procedure, the occlusal splint was installed as a palliative therapy for bruxism. This case report suggests that the dental approach by means of occlusal adjustment and occlusal splint, in a patient diagnosed with bruxism and temporomandibular disorder, reduces the signs and symptoms that affect the components of the Stomatognathic System.
A new species of Characidium (Characiformes: Crenuchidae) from the rio Doce basin, Brazil
Authors: Oliveira-Silva Leonardo , Santos Sérgio A. dos , Lopes Maridiesse Morais , Zanata Angela Maria
Published: March 2022

Abstract A new species of Characidium is described from the tributaries of the upper and middle rio Doce basin, Minas Gerais, Brazil. The new species is distinguished from most congeners, except C. cricarense, C. hasemani, C. helmeri, C. kalunga, C. pterostictum, C. schubarti, C. summus, and C. travassosi by lacking scales in the area between the anterior limit of the isthmus and the anterior margin of cleithrum. The new species differs from the aforementioned species by a series of characters, including the presence of the adipose fin, 2–4 scales between the anus and anal fin, two rows of dentary teeth, presence of the parietal branch of the supraorbital canal, 4 scale rows above the lateral line, and absence of two conspicuous inclined dark bands on each caudal-fin lobe. The new species further differs from most congeners with an unscaled ventral surface of the isthmus by the presence of 33–34 pored scales on the lateral line and by the dark dashes on the caudal fin-rays not forming well-defined bands.
New small-sized species of Astyanax (Characiformes: Characidae) from the upper rio Paraguai basin, Brazil, with discussion on its generic allocation
Authors: Dagosta Fernando C. P. , Marinho Manoela M. F.
Published: March 2022

Abstract A new species of Astyanax is described from the rio Salobra, tributary of rio Cuiabá, rio Paraguai basin. The new taxon can be distinguished from its congeners by having a well-defined dark midlateral stripe on body extending from the posterior margin of the opercle to the base of middle caudal-fin rays and a single vertical elongate humeral blotch. Although the new species is described in Astyanax, some specimens present an incomplete or a discontinuous series of perforated scales in the lateral line. Therefore, a discussion on its generic allocation is presented. Comments on different patterns of coloration among dark-striped species of Astyanax are also provided. The discovery of a new species in an underwater tourist point relatively near a large urban center underscores that even fish species daily observed by hundreds of people in limpid waters may lack a formal taxonomic identity. Such finding also highlights how the megadiverse Brazilian freshwater ichthyofauna still needs efforts and investments to identify and describe new taxa.
Differences in biochemical, physiological and molecular response mechanisms of rice, weedy rice and barnyardgrass subjected to drought
Authors: Agostinetto Dirceu , Oliveira Cláudia , Langaro Ana Claudia , Silva Jéssica Dias Gomes da , Barbieri Geovana Facco
Published: March 2022

ABSTRACT The drought stress tolerance may differ among species and cultivars. The drought effect on plants depends on the impact on the plant’s physiological, biochemical and molecular processes, as well as on its ability to adapt under these conditions. This study aimed to evaluate the physiological and biochemical responses, and determine the expression of the genes OsAPX2, OsHSP24.15, OsHSP71.10 and OsHSP85.88 under drought conditions in rice, weedy rice and barnyardgrass. A greenhouse experiment was performed in a complete randomized design, with four replications and two factors: water conditions (well-watered and water deficit) and plant species [rice (Oryza sativa cv. Puitá), weedy rice (Oryza spp.) and barnyardgrass (Echinochloa spp.)]. Under drought conditions, the rice and weedy rice plants showed more cellular damage than the barnyardgrass, and the three species showed a reduced photosynthetic rate. C3 plants (rice and weedy rice) increased the damage to lipids and proteins at 5 days of drought. However, for C4 plants (barnyardgrass), the drought conditions did not affect the biochemical parameters. The expression of the OsHSP85.88 gene increased in the three plants exposed to water deficit.
O CUSTO DO ALUNO DAS 2.537 INSTITUIÇÕES DE EDUCAÇÃO SUPERIOR BRASILEIRAS: CAI UM MITO?
Authors: Bielschowsky Carlos Eduardo , Amaral Nelson Cardoso
Published: March 2022

RESUMO Este estudo apresenta uma modelagem para o cálculo do custo médio do aluno das 2.537 Instituições de Educação Superior brasileiras, dividindo-as em segmentos, tanto públicos quanto privados. O modelo utiliza informações contidas em bancos de dados nacionais, estabelecendo premissas a serem consideradas no cálculo dos recursos financeiros e no número de estudantes a serem considerados. É estabelecida, além disto, uma relação entre o custo e a presença da educação a distância nas Instituições de Educação Superior e discute-se sobre a existência de um mito na educação brasileira, o de que as universidades federais possuem custos anuais médios maiores que os das universidades particulares.
A VIOLÊNCIA URBANA E ESCOLAR NAS PERIFERIAS DE BRASÍLIA
Authors: Garcia-Silva Sullyvan , Lima Junior Paulo , Caruso Haydée
Published: March 2022

RESUMO Este artigo visa discutir as relações entre a violência escolar e urbana na região de Brasília. Por meio de uma análise exploratória multivariada de dados governamentais, buscou-se avaliar a associação entre indicadores de classe e violência. Os resultados mostram que a violência escolar é irredutível à violência urbana, podendo ser intensa em regiões consideradas muito seguras ou escassa em regiões consideradas violentas e periféricas. Crimes de desacato e agressão registrados na escola são tipicamente independentes das taxas de homicídios na vizinhança. Implicações para políticas públicas, evasão discente e trabalho docente são discutidas.
Validation of a one-tube nested real-time PCR assay for the detection of Cryptosporidium spp. in avian fecal samples
Authors: Santana Bruna Nicoleti , Ferrari Elis Domingos , Nakamura Alex Akira , Silva Giane Serafim da , Meireles Marcelo Vasconcelos
Published: March 2022

Abstract The aim of this study was to validate a one-tube nested real-time PCR assay followed by genetic sequencing to detect and identify Cryptosporidium species and genotypes in birds. A total of 443 genomic DNA extracted from avian fecal samples were analyzed by one-tube nested real-time PCR and conventional nested PCR. By one-tube nested real-time PCR, 90/443 (20.3%) samples were positive for Cryptosporidium spp. In contrast, 36/443 (8.1%) samples were positive for Cryptosporidium spp. by conventional nested PCR. The analytical sensitivity test showed that one-tube nested real-time PCR detects approximately 0.5 oocyst (2 sporozoites) per reaction. An evaluation of analytical specificity did not reveal amplification of microorganisms that commonly present nonspecific amplification with primers used for the diagnosis of Cryptosporidium spp. The repeatability analysis showed the same result in 27 out of 30 samples (90%). As for the reproducibility of one-tube nested real-time PCR, 24 of the 30 samples examined (80%) showed the same result. All the 90 samples amplified by one-tube real-time nested PCR were successfully sequenced, leading to the identification of C. baileyi, C. galli, C. meleagridis, C. proventriculi, and Cryptosporidium avian genotype I. Genetic sequencing of conventional nested PCR amplicons was successful in 10/36 (27.8%) of positive samples.
A phonological solution to allomorphy in Georgian nominal inflection
Authors: Fortuna Marcin
Published: March 2022

Georgian features three patterns of nominal inflection, which are dependent on the structure of the stem. The stem can be consonantal, vocalic truncating, and vocalic non-truncating, with the consequences for the shape of the inflectional suffixes. However, variants of each individual case suffix differ across the three stem types in unique ways, with no single pattern being used for more than one grammatical case. This could suggest a solution based on traditional allomorph selection from a predefined list of stored forms. The paper argues, however, that a phonological explanation of the pattern is possible when rich autosegmental representations are employed. The analysis is couched within the CVCV model of phonology (Scheer 2004).
Molecular weight distribution of fructans extracted from Agave salmiana leaves
Authors: Plascencia Arizbeth , Gutiérrez-Mora Antonia , Rodríguez-Domínguez José Manuel , Castañeda-Nava José Juvencio , Gallardo-Valdez Juan , Shimada Harumi , Camacho-Ruiz Rosa María
Published: March 2022

Background: In mezcal industry, Agave salmiana leaves are a crop residue and a potential source of fructans. Agave fructans are a soluble fiber that can act as prebiotic in gut microbiota.

Questions and Hypotheses: The molecular weight distribution of agave fructans extracted from leaves of Agave salmiana depends on the region where agaves growth and on the subspecies.

Studied species: Agave salmiana Otto ex Salm Dyck, spp. salmiana and Agave salmiana spp. crassispina.

Study site: Twelve municipalities from Guanajuato México were sampled: Ocampo, San Felipe, San Diego de la Unión, Victoria, Xichú, Atarjea, Dolores Hidalgo, Doctor Mora, Santa Catarina, Tierra Blanca, San Miguel Allende and Comonfort.

Methods: The base of the leaf close to the stem of Agave salmiana ssp. salmiana and A. salmiana ssp. crassispina plants, six years old, were harvested. Water s oluble carbohydrates were extracted, the content molecular weight distribution of fructans was determined by HPLC-SEC.

Results: An average of 0.7 % of soluble carbohydrates was recovered from the leaves. The molecular weight distribution of Agave salmiana fructans was: number average molecular weight: 3,209 g/mol; average molecular weight: 5,046 g/mol; number average degree of polymerization: 19; weight average degree of polymerization: 30. High polymerization degree fructans content was greater in Agave salmiana spp. salmiana (55 %) than in Agave salmiana spp. crassispina (47 %).

Conclusions: The leaves of Agave salmiana contain a low proportion of high-molecular-weight fructans, compared to commercial agave fructans. The results demonstrated the technical feasibility to obtain fructans from Agave salmiana leaves.
Il lavoro del medico: La legge, la deontologia
Authors: Loner Arnaldo
Published: March 2022

Gli esseri umani stanno insieme, vivono insieme. Sono milioni nelle grandi capitali, poche migliaia nei piccoli centri. Il loro stare vicini cagiona e promuove incontri, relazioni, rapporti. Anche contrasti. Sono necessarie delle regole, una disciplina. Questo per ogni settore delle molteplici attività umane. La sanità rappresenta un elemento essenziale nella vita delle comunità e sussiste una particolare necessità di regolamentare compiutamente lo svolgimento di questa indispensabile attività di protezione della vita e della salute dell’uomo. Lo stato, con il parlamento e le istituzioni locali provvedono a disciplinare in modo dettagliato con specifiche disposizioni legislative il funzionamento delle organizzazioni sanitarie e il lavoro degli operatori sanitari. Vi sono numerose leggi che obbligano tutti i cittadini, non soltanto gli addetti alla sanità, all’applicazione ed al rispetto delle disposizioni.
[RETRACTED] Ketosium XS Keto Reviews Why Keto Dietary Plan Is Necessary Get All Answers In This Article (Work Or Hoax) v1
Authors: XS Keto Ketosium
Published: March 2022

[RETRACTED]

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[RETRACTED] Ketosium XS Keto Reviews : - Get The Best Version of Your Body With Keto Pills | Perfect for USA & UK v1
Authors: XS Keto Ketosium
Published: March 2022

[RETRACTED]

Ketosium XS Keto Reviews : - Get The Best Version of Your Body With Keto Pills | Perfect for USA & UK
DNA extraction from insect gut-dwelling fungi v1
Authors: Wang Yan
Published: March 2022

This protocol is good for DNA extraction from microbial fungi isolated from aquatic insect guts. It works for small input tissues (starting from one fungal thallus). The product can be used for PCR and Sanger sequencing directly, which is ideal for fungal barcode analyses. This protocol is modified from a method described in Gottlieb and Lichtwardt 2001 (Mycologia Vol. 93, No. 1, pp. 66-81).
[RETRACTED] True Science Anti Aging Cream - Where to buy it? v1
Authors: not provided truescienceagingcream
Published: March 2022

[RETRACTED]

True Science Anti Aging Cream - Where to buy it?
Purifying Vps13-VAB domain proteins v1
Authors: not provided jyoti.adlakha
Published: March 2022

In this protocol, we have listed the steps to purify the Vps13 adaptor binding domain (or VAB) with or without PxP motif fusion peptide derived from adaptor proteins Mcp1, Ypt35 or Spo71.
Experience in managing severe and extremely severe COVID-19 in pregnant women
Authors: Gareyeva Aygul I. , Mozgovaya Elena V. , Belopolskaya Maria A. , Kovalchuk Alexey S. , Kucheryavenko Alexandr N.
Published: March 2022

BACKGROUND: In the context of the COVID-19 pandemic caused by the SARS-CoV-2 virus, viral pneumonia is the leading clinical form of coronavirus infection and a significant cause of maternal mortality.
AIM: The aim of this study was to assess the course of severe and extremely severe forms of COVID-19, its impact on pregnancy and fetus, as well as on maternal mortality.
MATERIALS AND METHODS: In this retrospective study, we evaluated 39 case histories of patients with severe and extremely severe COVID-19, which were divided into two groups. Group 1 included 22 pregnant women with a severe course of coronavirus infection and a favorable outcome. Group 2 comprised 17 pregnant women in whom complications caused by SARS-CoV-2 were fatal.
RESULTS: More than 80% of patients with severe disease course had anaemia in pregnancy. The most significant clinical and anamnestic factors of adverse outcome were gestational diabetes mellitus (p = 0.02), preeclampsia (p = 0.05), and oligoamnios (p = 0.01). Obesity in group 2 was twice more common. The clinical manifestations of the disease in the both study groups were dominated by fever, shortness of breath, weakness and dry cough. In patients with a fatal outcome at the height of the disease, the levels of leukocytosis, urea and lactate dehydrogenase were higher than in those who recovered (p = 0.05). Besides, the levels of alanine transferase and aspartate transaminase were twice as high as in pregnant women who recovered later. Patients in the both study groups required oxygen support as respiratory failure progressed. The vast majority of patients with severe and extremely severe forms of coronavirus infection were in the third trimester of pregnancy.
CONCLUSIONS: Women in the third trimester of pregnancy are more susceptible to severe and extremely severe COVID-19 with an unfavorable outcome. Gestational diabetes mellitus, preeclampsia and oligoamnios are significant comorbidities that predispose to severe course and poor outcome in pregnant women and puerperas with COVID-19. The characteristic clinical manifestations of the severe course of coronavirus infection are shortness of breath and fever against a backdrop of significant damage to the lung tissue. A pronounced increase in hepatic enzymes and placental insufficiency is a harbinger of an unfavorable outcome as a manifestation of multiple organ failure.
Stabilization of theS-to-PEnergy Ratio of a Diffuse Wavefield from Reflections at Free Surfaces
Authors: Nagasaka Yosuke , Nozu Atsushi
Published: March 2022

Seismic interferometry relates the Green’s function between two observation sites to the cross correlation of recordings at these sites. In the formulation of seismic interferometry to retrieve the exact Green’s function, an assumption that the energy density ratio of S-to-P waves is 2(α/β)3 is used. Thus, understanding how and under what conditions a wavefield satisfies this energy partition ratio is important for these studies. Previous studies revealed that multiple scattering by random inhomogeneities of the medium equilibrates the S- to P-wave energy densities, and the ratio is 2(α/β)3. However, the effect of the free surface on the energy partition ratio is not fully understood. This study analyzes the effect of the free surface to the energy density ratio in a diffuse wavefield. We employ the definition of a diffuse wavefield by a random superposition of plane waves. We consider a wavefield where plane waves travel inside a homogeneous solid with a free surface and repeat P-to-S and S-to-P conversions at the free surface. Under this condition, it is known that the energy density ratio of S-to-P waves tends to a specific value. However, the value proposed in a previous study slightly deviated from 2(α/β)3, and it was argued that the deviation was due to a numerical error. We prove that the ratio exactly equals 2(α/β)3. Our results show that repeated reflections at the free surface as well as scattering in random media equilibrate the energy ratio of S-to-P waves into 2(α/β)3 regardless of the energy partition of the source.
The Impact of Lackawanna County's Arts, Culture, and Education Tax
Authors:   , Carestia Melissa A. , Gibbs Amy
Published: March 2022

This study examines how public funding for the arts through earmarked taxes is beneficial to communities, specifically in Lackawanna County, PA. With data from grant reports, surveys, and interviews, my goal for this research was to see the level of impact that the Lackawanna County Arts, Culture and Education Tax has had in Lackawanna County and if the tax is a viable funding method. For this research, both qualitative and quantitative data were used. The qualitative data was gathered through interviews with leaders from the community including Lackawanna County's Arts and Culture Department, the City of Scranton's Office of Economic and Community Development, and the Lackawanna County Convention & Visitors Bureau. In addition to interviews, I conducted an audience survey about arts and culture participation in Lackawanna County which gave insight into the community's perception of arts and culture in the county along with some of their audience habits. The quantitative data was collected from Lackawanna County's Arts and Culture grant reports and from SMU DataArts's Cultural Data Project. This data was compared to find trends with programs, audience attendance, and organizational budgets. Through this research, I found that elimination of the tax would do harm to the arts and culture sector. It was difficult to measure the full impact of the tax with the data that is available, mostly due to inconsistent data among the different reporting structure. Overall, the data showed that organizations are using the funds granted to them for programming and operations. The interviews and survey brought up many positive aspects of the relationship between arts and culture and the county, however without the support of the quantitative data it is challenging to draw a definitive conclusion on the full level of impact. By examining current processes and procedures in place and looking at examples of dedicated taxes in other communities, I was able to create some recommendations for the administration of the grants funding by Lackawanna County's Arts, Culture, and Education tax. I believe that these recommendations can help establish better ways to measure the tax's impact and success.
Афганский кризис как глобальная и региональная проблема международного сообщества
Authors: Кокошин Андрей , Кокошина Злата
Published: March 2022

В статье рассматривается комплекс вопросов, связанных с нынешним афганским кризисом – таких, как подход к нему на глобальном и региональном уровнях различных государств (с противоречиями и разногласиями между ними); экономическое и внутриполитическое положение Афганистана и проблемы предотвращения масштабной гуманитарной катастрофы; вопросы легитимности временного правительства талибов в глазах международного сообщества и проблема его признания; террористическая угроза со стороны Афганистана после захвата власти талибами; проблема производства и распространения наркотиков. Авторы кратко анализируют предысторию кризиса, в том числе ряд характеристик предыдущего режима талибов (1996-2001). Подчеркивается, что афганский кризис имеет глубокий, масштабный и затяжной характер, что он чреват разного рода обострениями, в том числе с самыми негативными последствиями для стран Центральной Азии, в безопасности и стабильности которых кровно заинтересована Россия.
«Дипломатия для науки» в интерпретации российских научных и дипломатических работников
Authors: Райнхардт Роман , Панов Александр
Published: March 2022

В статье рассматривается роль “дипломатии для науки” как одного из направлений научной дипломатии по поддержке и осуществлению международного научно-технического сотрудничества (МНТС). Авторы выделяют два уровня реализации практик дипломатии для науки, а именно макроуровень, на котором заключаются межгосударственные соглашения об МНТС, и микроуровень, предполагающий поддержку дипломатами конкретных ученых и научных коллективов в их взаимодействии с иностранными контрагентами. С целью выявления важнейших проблем, стоящих и перед научными, и перед дипломатическими работниками прежде всего на микроуровне, авторы провели серию полуструктурированных интервью с представителями русскоязычного научного сообщества и работниками Министерства иностранных дел России. В ходе данных бесед удалось установить, во-первых, что ученые сталкиваются с недостатком информации по консульского-визовым и юридическим вопросам, что вкупе с бюрократическими проволочками может отрицательно влиять на решения об активном поддержании научных контактов с зарубежными партнерами. Во-вторых, низкий уровень консолидации так называемой научной диаспоры зачастую подрывает усилия по координации российских и русскоязычных ученых за рубежом. У дипломатов, в свою очередь, возникает ряд проблем, связанных с отсутствием формально закрепленных понятий “ученый” и “научная диаспора”, что приводит к сложностям в определении круга возможных получателей консульской и дипломатической поддержки. И ученые, и дипломаты указывают на трудности коммуникации, которая обусловливается в том числе низким уровнем взаимного доверия. На основании полученных эмпирическим путем данных авторами сформулирован ряд рекомендаций, нацеленных на оптимизацию применяемых практик. К ним относятся: в части консульско-визовой проблематики – выделение поездок в рамках МНТС в отдельную визовую категорию и разработка проекта “паспорта ученого” по модели “паспорта болельщика”; в части работы с научной диаспорой – выработка четкого определения данного понятия, упрощение правил въезда и получения гражданства РФ для лиц, причисляемых к российской научной диаспоре; в части информационно-разъяснительной работы – активизация работы профильных информационных ресурсов и создание объединяющей их специализированной интернет-платформы.
Design and Control of Electronic Syringe Pump using AVR Microcontroller
Authors: Zope Pankaj H. , Suralkar Shekhar R.
Published: March 2022

The infusion and retract rate of the electronic syringe injection pump is one of the major challenge in the designing and control of electrospinning system. The selective droplet materials of a small size with controlled structured and patterned is released through a needle of the syringe pump very important. This investigation focuses on control parameter like infusion and retract rate, flow rate, the droplet volume, and syringe size dimension. It is observed the infusion rate 1ml for 5.7sec to 7.11 sec, retract rate 1ml for 1600-2000 signals pulses of stepper motor, the droplet volume is 0.0001 to 0.02ml increasing after every 300-500 signal pulses observed on CRO with different types of syringe injection pump. It is observed that the average error for the measured flow rate is 10% and average error for the measured volume is 1.91%. In this study the design and control of low cost and simple system is discussed using prototype of electronic syringe injection pump designed using AVR microcontroller for changeable and small delivery rates for the control of low volumes.