bluuebunny/crossref_metadata_2025 huggingface dataset:
O queijo e os vermes: o cosmo de um historiador do século XX
Authors: LaCapra Dominick
Published: July 2015

O queijo e os vermes: o cosmo de um historiador do século XX foi originalmente publicado em History & Criticism, de 1985, coletânea de ensaios de Dominick LaCapra. Abertamente polêmico, realiza uma leitura cerrada de um texto clássico da historiografia do século XX, O queijo e os vermes (1976), de Carlo Ginzburg, buscando, por aí, explicitar e problematizar certas tendências, então - e ainda -, predominantes na profissão histórica. O propósito de LaCapra é chamar a atenção dos historiadores para a necessidade de refletir sobre sua prática e desenvolver modos de interpretação mais críticos e autocríticos, num diálogo mais próximo com a crítica literária e a filosofia contemporânea. Ao traduzi-lo para o português, visamos contribuir para tornar a obra de LaCapra mais disseminada entre o público acadêmico brasileiro.
Anatomical basis for the intrahepatic glissonian approach during hepatectomies
Authors: SURJAN Rodrigo Cañada Trofo , MAKDISSI Fábio Ferrari , MACHADO Marcel Autran Cesar
Published: July 2015

BACKGROUND: Anatomical liver resections are based on some basic technical principles such as vascular control, ischemic area delineation to be resected and maximum parenchymal preservation. These aspects are achieved by the intrahepatic glissonian approach, which consists in accessing the pedicles of hepatic segments within the hepatic parenchyma. Small incisions on well-defined anatomical landmarks are performed to approach the pedicles, making dissection of the hilar plate unnecessary. AIM: Analyze parameters in liver anatomy related to intrahepatic surgical technique to glissonians pedicles, to set the normal anatomy related to the procedure and thereby facilitate the attainment of this technique. METHODS: Anatomical parameters related to the intrahepatic glissonian approach were studied in 37 cadavers. Measurements were performed with precision instruments. Data were expressed as mean±standard deviation. The subjects were divided into groups according to gender and liver weight and groups were compared statistically. RESULTS: Twenty-five cadavers were male and 12 female. No statistically significant difference was observed in virtually all parameters when groups were compared. This demonstrates the consistency of the anatomical parameters related to the intrahepatic glissonian approach. CONCLUSION: The results obtained in this study made possible major technical advances in the realization of open and laparoscopic hepatectomies with intrahepatic glissonian approach, and can help surgeons to perform liver resections by this method.
Simplified technique for auxiliary orthotopic liver transplantation using a whole graft
Authors: ROCHA-SANTOS Vinicius , NACIF Lucas Souto , PINHEIRO Rafael Soares , DUCATTI Liliana , ANDRAUS Wellington , D'ALBURQUERQUE Luiz Carneiro
Published: July 2015

BACKGROUND: Acute liver failure is associated with a high mortality rate and the main purposes of treatment are to prevent cerebral edema and infections, which often are responsible for patient death. The orthotopic liver transplantation is the gold standard treatment and improves the 1-year survival. AIM: To describe an alternative technique to auxiliary liver transplant on acute liver failure. METHOD: Was performed whole auxiliary liver transplantation as an alternative technique for a partial auxiliary liver transplantation using a whole liver graft from a child removing the native right liver performed a right hepatectomy. The patient met the O´Grady´s criteria and the rational to indicate an auxiliary orthotopic liver transplantation was the acute classification without hemodynamic instability or renal failure in a patient with deterioration in consciousness. RESULTS: The procedure improved liver function and decreased intracranial hypertension in the postoperative period. CONCLUSION: This technique can overcome some postoperative complications that are associated with partial grafts. As far as is known, this is the first case of auxiliary orthotopic liver transplantation in Brazil.
Late surgical complications after gastric by-pass: a literature review
Authors: PALERMO Mariano , ACQUAFRESCA Pablo A. , ROGULA Tomasz , DUZA Guillermo E. , SERRA Edgardo
Published: July 2015

INTRODUCTION: Gastric bypass is today the most frequently performed bariatric procedure, but, despite of it, several complications can occur with varied morbimortality. Probably all bariatric surgeons know these complications, but, as bariatric surgery continues to spread, general surgeon must be familiarized to it and its management. Gastric bypass complications can be divided into two groups: early and late complications, taking into account the two weeks period after the surgery. This paper will focus the late ones. METHOD: Literature review was carried out using Medline/PubMed, Cochrane Library, SciELO, and additional information on institutional sites of interest crossing the headings: gastric bypass AND complications; follow-up studies AND complications; postoperative complications AND anastomosis, Roux-en-Y; obesity AND postoperative complications. Search language was English. RESULTS: There were selected 35 studies that matched the headings. Late complications were considered as: anastomotic strictures, marginal ulceration and gastrogastric fistula. CONCLUSION: Knowledge on strategies on how to reduce the risk and incidence of complications must be acquired, and every surgeon must be familiar with these complications in order to achieve an earlier recognition and perform the best intervention.
Mobility therapy and central or peripheral catheter-related adverse events in an ICU in Brazil
Authors: Lima Natália Pontes , Silva Gregório Marques Cardim da , Park Marcelo , Pires-Neto Ruy Camargo
Published: July 2015

OBJECTIVE: To determine whether mobility therapy is associated with central or peripheral catheter-related adverse events in critically ill patients in an ICU in Brazil. METHODS: A retrospective analysis of the daily medical records of patients admitted to the Clinical Emergency ICU of the University of São Paulo School of Medicine Hospital das Clínicas Central Institute between December of 2009 and April of 2011. In addition to the demographic and clinical characteristics of the patients, we collected data related to central venous catheters (CVCs), hemodialysis (HD) catheters and indwelling arterial catheters (IACs): insertion site; number of catheter days; and types of adverse events. We also characterized the mobility therapy provided. RESULTS: Among the 275 patients evaluated, CVCs were used in 49%, HD catheters were used in 26%, and IACs were used in 29%. A total of 1,268 mobility therapy sessions were provided to patients while they had a catheter in place. Catheter-related adverse events occurred in 20 patients (a total of 22 adverse events): 32%, infection; 32%, obstruction; and 32%, accidental dislodgement. We found that mobility therapy was not significantly associated with any catheter-related adverse event, regardless of the type of catheter employed: CVC-OR = 0.8; 95% CI: 0.7-1.0; p = 0.14; HD catheter-OR = 1.04; 95% CI: 0.89-1.21; p = 0.56; or IAC-OR = 1.74; 95% CI: 0.94-3.23; p = 0.07. CONCLUSIONS: In critically ill patients, mobility therapy is not associated with the incidence of adverse events involving CVCs, HD catheters, or IACs.
Diagnostic yield of endobronchial ultrasound-guided transbronchial needle aspiration for mediastinal staging in lung cancer
Authors: Fernández-Bussy Sebastián , Labarca Gonzalo , Canals Sofia , Caviedes Iván , Folch Erik , Majid Adnan
Published: July 2015

OBJECTIVE: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive diagnostic test with a high diagnostic yield for suspicious central pulmonary lesions and for mediastinal lymph node staging. The main objective of this study was to describe the diagnostic yield of EBUS-TBNA for mediastinal lymph node staging in patients with suspected lung cancer. METHODS: Prospective study of patients undergoing EBUS-TBNA for diagnosis. Patients ≥ 18 years of age were recruited between July of 2010 and August of 2013. We recorded demographic variables, radiological characteristics provided by axial CT of the chest, location of the lesion in the mediastinum as per the International Association for the Study of Lung Cancer classification, and definitive diagnostic result (EBUS with a diagnostic biopsy or a definitive diagnostic method). RESULTS: Our analysis included 354 biopsies, from 145 patients. Of those 145 patients, 54.48% were male. The mean age was 63.75 years. The mean lymph node size was 15.03 mm, and 90 lymph nodes were smaller than 10.0 mm. The EBUS-TBNA method showed a sensitivity of 91.17%, a specificity of 100.0%, and a negative predictive value of 92.9%. The most common histological diagnosis was adenocarcinoma. CONCLUSIONS: EBUS-TBNA is a diagnostic tool that yields satisfactory results in the staging of neoplastic mediastinal lesions.
PET/CT imaging in lung cancer: indications and findings
Authors: Hochhegger Bruno , Alves Giordano Rafael Tronco , Irion Klaus Loureiro , Fritscher Carlos Cezar , Fritscher Leandro Genehr , Concatto Natália Henz , Marchiori Edson
Published: July 2015

The use of PET/CT imaging in the work-up and management of patients with lung cancer has greatly increased in recent decades. The ability to combine functional and anatomical information has equipped PET/CT to look into various aspects of lung cancer, allowing more precise disease staging and providing useful data during the characterization of indeterminate pulmonary nodules. In addition, the accuracy of PET/CT has been shown to be greater than is that of conventional modalities in some scenarios, making PET/CT a valuable noninvasive method for the investigation of lung cancer. However, the interpretation of PET/CT findings presents numerous pitfalls and potential confounders. Therefore, it is imperative for pulmonologists and radiologists to familiarize themselves with the most relevant indications for and limitations of PET/CT, seeking to protect their patients from unnecessary radiation exposure and inappropriate treatment. This review article aimed to summarize the basic principles, indications, cancer staging considerations, and future applications related to the use of PET/CT in lung cancer.
Acetolactate Synthase–Inhibitor–Resistant Yellow Nutsedge (Cyperus esculentus): I—Phenotypic Differences
Authors: Bagavathiannan Muthukumar V. , Norsworthy Jason K. , Tehranchian Parsa , Riar Dilpreet S.
Published: July 2015

Acetolactate synthase (ALS) –inhibitor resistance has been recently documented in a yellow nutsedge biotype in Arkansas rice production, with a target-site mutation resulting in an amino acid substitution from Trp574 to Leu. Preliminary observations have indicated that the resistant biotype showed distinct phenotypic characteristics. Two greenhouse experiments were conducted on the resistant biotype in comparison with three susceptible standards (1) to understand differential growth habit and spatial distribution, and (2) to characterize shoot emergence pattern and seedling vigor. The resistant biotype exhibited a drastically different growth habit with secondary and tertiary basal bulbs emerging away from the parent shoot, resulting in a wider spatial distribution and ground coverage compared to the very compact growth habit of susceptible biotypes. Unlike the susceptible biotypes, the rhizomes developing into tubers were not often connected to the primary basal bulb, but were originating randomly from daughter shoots. The resistant biotype produced an extensive subterranean network of rhizomes and basal bulbs, with wider root spread and distribution compared to the susceptible biotypes. The growth habit of the resistant biotype appeared to be intermediate between yellow and purple nutsedges. Further, the resistant biotype showed a considerably delayed emergence pattern with relatively high levels of tuber dormancy. Although the resistant plants exhibited low early-growth seedling vigor and biomass production compared to the susceptible biotypes (perhaps because of smaller tubers), final aboveground biomass production was greater than that of susceptible biotypes. The overall growth habit and phenotype of the resistant biotype may provide a competitive advantage over adjacent species through the ability to occupy niches and gain improved access to critical resources. The distinct growth pattern may also mean that tillage should not be relied upon for control because it can assist further spread by disconnecting and displacing the chains of rhizomes.
Fracture parameters of site-cast dam and sieved concrete
Authors: Guan Junfeng , Li Qingbin , Wu Zhimin , Zhao Shunbo , Dong Wei , Zhou Shaowu
Published: July 2015

A conversion relationship between the fracture parameters of site-cast dam concrete and that of sieved concrete is presented. The concrete mixture produced by the mixing tower system on the construction site of a super-high arch dam was used to cast and mould different sized specimens. The maximum aggregate size for the dam concrete specimens was 150 mm and that for the sieved concrete specimens was 40 mm. The fracture parameters of the dam concrete and sieved concrete, including fracture energy, effective fracture toughness, critical crack tip opening displacement and characteristic length, were determined. In addition, the effect of dam concrete and sieved concrete specimen size on fracture behaviour was analysed. It was found, regardless of the dam concrete or sieved concrete specimen, that when the ratio of the ligament height to the maximum aggregate size was equal to or greater than 6·0, stable values of the fracture parameters were obtained. Based on the test results, formulae for calculating the fracture parameters for large dam-concrete specimens were derived from those for small sieved-concrete specimens.
Roma Children and Young People in Bulgaria: Patterns of Risk and Effective Protection in Relation to Child Sexual Exploitation
Authors: D'Arcy Kate , Brodie Isabelle
Published: July 2015

This article examines patterns of risk regarding child sexual exploitation (CSE). There is specific focus on those living in alternative care, child sexual exploitation and trafficking among Roma communities in Bulgaria and the UK. Data is drawn from a desk-based literature review and partnership work with Bulgarian and British academics and practitioners to explore the issues in both countries. Although there is limited statistical data on CSE and children in care across Europe and the risk-factors for Roma children and young people are still not being fully recognised, we can draw on what is known in Bulgaria to inform practice in the UK with emerging Roma communities. Research on CSE more generally can also inform awareness of risk factors particularly around care systems. Comparative information about what is known in the UK and Bulgaria is considered in order to make some recommendations for international prevention, protection efforts, and prosecution strategies for the future.
Atividade fotossintética da beterraba submetidas a adubação mineral e esterco bovino
Authors: Gondim Ancélio Ricardo de Oliveira , Santos José Lucas Guilherme , Lira Renato Pereira , Brito Marcos Eric Barbosa , Pereira Francisco Hevilásio Freire
Published: July 2015

O presente trabalho foi desenvolvido com o objetivo avaliar os efeitos da adubação mineral e esterco bovino sobre as trocas gasosas em plantas de beterraba. O experimento foi conduzido em condições de campo, com delineamento em blocos casualizados, no esquema fatorial 5 x 2, com três repetições. Os tratamentos serão constituídos por cinco doses de esterco bovino (2,0; 4,0; 6,0; 8,0; e 10,0 kg m-2), na presença e ausência de adubo mineral. Foram avaliados os seguintes parâmetros: fotossíntese liquida (A), a condutância estomática (gs), a transpiração (E) e a concentração intercelular de CO2 (Ci), eficiência instantânea do uso da água (A/E), eficiência de carboxilação (A/Ci). As plantas de beterraba cultivadas na presença da adubação mineral e com a maior dose de esterco revelaram valores maiores para condutância estomática. O tratamento de 10,0 kg m-2 de esterco apresentou maior taxa de fotossíntese. Os valores de transpiração e concentração intercelular de CO2 na beterraba foram influenciados pelas doses de esterco.
Nested species‐rich networks of scavenging vertebrates support high levels of interspecific competition
Authors: Sebastián‐González Esther , Moleón Marcos , Gibert Jean P. , Botella Francisco , Mateo‐Tomás Patricia , Olea Pedro P. , Guimarães Paulo R. , Sánchez‐Zapata José A.
Published: July 2015

Disentangling the processes that shape the organization of ecological assemblages and its implications for species coexistence is one of the foremost challenges of ecology. Although insightful advances have recently related community composition and structure with species coexistence in mutualistic and antagonistic networks, little is known regarding other species assemblages, such as those of scavengers exploiting carrion. Here we studied seven assemblages of scavengers feeding on ungulate carcasses in mainland Spain. We used dynamical models to investigate if community composition, species richness and structure (nestedness) affect species coexistence at carcasses. Scavenging networks showed a nested pattern in sites where highly efficient, obligate scavengers (i.e., vultures) were present and a non‐nested pattern everywhere else. Griffon Vulture (Gyps fulvus) and certain meso‐facultative mammalian scavengers (i.e., red fox, Vulpes vulpes, and stone marten, Martes foina) were the main species contributing to nestedness. Assemblages with vultures were also the richest ones in species. Nested species‐rich assemblages with vulture presence were associated with high carcass consumption rates, indicating higher interspecific competition at the local scale. However, the proportion of species stopping the consumption of carrion (as derived from the competitive dynamic model) stabilized at high richness and nestedness levels. This suggests that high species richness and nestedness may characterize scavenging networks that are robust to high levels of interspecific competition for carrion. Some facilitative interactions driven by vultures and major facultative scavengers could be behind these observations. Our findings are relevant for understanding species’ coexistence in highly competitive systems.
The role of resource limitation in restoration of sagebrush ecosystems dominated by cheatgrass (Bromus tectorum)
Authors: Jones Rachel O. , Chambers Jeanne C. , Board David I. , Johnson Dale W. , Blank Robert R.
Published: July 2015

Success of invasive annual grasses is often linked to increases in resources, and restoration ecologists have suggested that decreasing nitrogen (N) availability and restoring more conservative N cycles with lower N turnover should decrease the competitive advantage of these invaders and facilitate establishment of native perennials. We developed a multivariate conceptual model of the likely effects of environmental factors (precipitation and temperature) and potential management treatments (repeated burning, litter manipulation, and seeding an annual competitor) on soil N availability and success of cheatgrass, the most widespread invader in the western United States. We examined effects of the treatments in a five year field study in a cold desert shrubland. We used generalized linear mixed‐effects models to examine differences among treatments over time, and structural equation modeling (SEM) to evaluate component hypotheses of the conceptual model. We hypothesized that burning would result in a pulse in soil available N due to heat‐induced soil organic matter denaturation, but that subsequent fires would volatilize soil and biomass N resulting in progressive N deficiency. However, soil available N in burned plots was never lower than pre‐burn levels, likely because burn temperatures were too cool to volatilize N from soils or aboveground biomass. Repeated burning decreased litter biomass, but there were generally no differences in soil available N between litter intact and litter removed plots. Litter removal had a negative effect on cheatgrass success likely due to effects on seed entrapment and plant establishment rather than N mineralization. Plots seeded with wheat generally had the lowest cheatgrass success, but available N was similar to other treatments, and decreased cheatgrass success was likely due to competition for other soil nutrients or water and reduced litter. In this semi‐arid shrubland, long‐term trends in available soil N and cheatgrass success were most strongly associated with precipitation and winter minimum temperatures. Treatments did not result in longer‐term decreases in soil N, but indicated that integrated restoration approaches that reduce litter and seed banks and increase competitive interactions may be effective at reducing cheatgrass success and facilitating establishment of natives.
Optimization of Process on Extracting Flavonoids from Dry Onion Skins by Alkaline Method
Authors: Guoqing Shi , Qisen Xiang , Yichao Fan , Wenen Zhao , Yanqi Liu
Published: July 2015

The flavonoids in dry onion skins were extracted by alkaline solution method. On the basis of single factor combined with ternary quadratic regression general rotary unitized design, the effects of several extraction parameters on the extraction efficiency of total flavonoids were investigated, including extraction times, pH of the extraction solution, material / extraction solution ratio, extraction time, and temperature. NaNO2-Al(NO3)3-NaOH method was used for the determination of total flavonoids. The optimal extraction conditions were as follows: two times of extraction; pH, 11; material / extraction solution ratio, 30 : 1; extraction temperature, 83.0 ~ 84.0 °C; extraction duration, 1.9 ~ 2.0 h. Under the above optimal conditions, the flavonoids extracted from dry onion skins yielded 2.82%.
The Synthesis of New Solid-phase Microextraction Adsorption Material and Its Adsorption Performance
Authors: Shuang Fu , Chunhui Xia , Hongmei Li , Feng Xu
Published: July 2015

This article uses three kinds of monomers: the styrene, butyl acrylate and Vinyltriisopropoxysilane, synthesized the solid phase micro extract coating adsorption material, carries on the structure characterization and the physical performance test. Takes it as the solid phase micro extract coating, carries on the inspection to its adsorbability, the experiment obtains the detection limit of the benzene which is 0.21 µ g/L; The detection limit of the toluene is 30 µ g/L; The detection limit of the m-Xylene is 0.55 µ g/L. Indicated the adsorptivity of this polymer has more effection toward the small molecular aromatic hydrocarbon as the solid phase micro extract coating adsorption material, and the limit of detection is lower compared to the commodity extract coating, there are some promotion and adoption value.
Tsunami Loading Analysis and Engineering Prevention and Control
Authors: Wang Tiecheng , Meng Tao , Zhao Hailong
Published: July 2015

Tsunami is one of the serious natural disasters in coastal areas. Tsunami waves produce huge horizontal thrust
on costal buildings, resulting in a large number of houses collapsed instantaneously, causing serious casualties and
economic losses. Based on a reinforced concrete frame structure under different conditions of tsunami effect analysis, this
paper clarified the calculation method of tsunami loading and proposed two kinds of the most disadvantageous
combination effects of the tsunami loading, namely the combination effect of the advancing water front of a tsunami and
the combination effect of the tsunami inundation. It is indicated that the right structure type and the multi-story or highrise
buildings should be chosen in the tsunami damage prevention and control measures, and the ability of the key loadbearing
members to resist tsunami impact at the bottom of the structure should be strengthened.
Improved Total Least Square Algorithm
Authors: Yonghe Deng
Published: July 2015

Aim to blemish of total least square algorithm based on error equation of virtual observation,this paper
proposed a sort of improved algorithm which doesn’t neglect condition equation of virtual observation,and considers both
error equation and condition equation of virtual observation.So,the improved algorithm is better.Finally,this paper has
fitted a straight line in three-dimensional space based on the improved algorithm.The result showed that the improved
algorithm is viable and valid.
GC/MS Analysis of Fatty Acids in Italian Dry Fermented Sausages
Authors: Liguori Angelo , Belsito Emilia Lucia , Gioia Maria Luisa Di , Leggio Antonella , Malagrinò Francesca , Romio Emanuela , Siciliano Carlo , Tagarelli Antonio
Published: July 2015

The present investigation reports a study about the evolution, during ripening, of the fatty acid profile and the
fatty acid composition in acylglycerols of three different fermented sausages industrially produced in the Calabria region
(Southern Italy). Statistical analysis (ANOVA) was applied to the results obtained for the profiles to check all the
differences between samples. The study comprised also an evaluation of the lipid oxidation level. All kind of sausages
showed a free fatty acids profile in which the monounsaturated fatty acids were predominant, followed by saturated and
polyunsaturated fatty acids. In acylglycerols, a low content in linoleic acid (approximately 2% of total methyl esters) was
displayed, while that found in the free fatty acids profile was higher (approximately 17% of total FFAs). In addition, the
generation of aldehydes through secondary lipid oxidation was clearly confirmed after long ripening period by classical
qualitative colorimetric method supported by 1H NMR spectroscopy. The differences in fatty acids profiles observed in
the free fatty acids and the acylglycerol fractions were certainly due to the high selectivity of lypase activity during the
ripening.
The Migration of Chemical Contaminants from Polyethylene Bags into Food During Cooking
Authors: Musoke L. , Banadda N. , Sempala C. , Kigozi J.
Published: July 2015

Cooking food in polyethylene bags has of late substituted banana leaves in Uganda. However, such a practice is
risky as chemical contaminants may migrate from polyethylene bags into food during cooking causing health
complications. Therefore, this study was done to identify and quantify the levels of chemical contaminants (heavy metals)
in black and green polyethylene bags. Polyethylene bags were ashed and digested with acid and heavy metal
concentrations determined using an AAS. Samples analyzed contained heavy metals with concentrations ranging between;
1125 - 1725, 76 - 112, 35 - 52, 18 - 31 ppm for Pb, Cd, Cr and Co respectively. Heavy metal migration studies into posho
cooked in the black polyethylene bags was done at 65°C (T), 80°C (T) and 95°C (T). The highest migrated heavy metal
concentrations 120.60, 12.25, 9.45 and 15.42 ppm for Pb, Cd, Cr and Co respectively were obtained at T3 at the surface of
the posho cube (0.5cm) after 5 hours of heating. While the lowest values for Pb (10.60 ppm), Cd (1.26 ppm), Cr (0.20 ppm)
and Co (1.55 ppm) were obtained at T1 towards the centroid of the posho cube (1.5 cm) after 2 hours of heating. Pb
migrated highest followed by Co, Cr and Cd. Though small quantities migrated, over a long period of time they may
accumulate in the body and cause health complications to the victims. To make this research of substantial importance to
the polyethylene bag user, the findings were disseminated through media to the general public.
How Patients Contribute to an Online Psychoeducation Forum for Bipolar Disorder: A Virtual Participant Observation Study
Authors: Poole Ria , Smith Daniel , Simpson Sharon
Published: July 2015

Background

In a recent exploratory randomized controlled trial, an online psychoeducation intervention for bipolar disorder has been found to be feasible and acceptable to patients and may positively impact on their self-management behaviors and quality of life.

Objective

The objective of the study was to investigate how these patients contribute to an online forum for bipolar disorder and the issues relevant for them.

Methods

Participants in the intervention arm of the Bipolar Interactive PsychoEDucation (“BIPED”) trial were invited to contribute to the Beating Bipolar forum alongside receiving interactive online psychoeducation modules. Within this virtual participant observation study, forum posts were analyzed using thematic analysis, incorporating aspects of discourse analysis.

Results

The key themes which arose from the forum posts included: medication, employment, stigma, social support, coping strategies, insight and acceptance, the life chart, and negative experiences of health care. Participants frequently provided personal narratives relating to their history of bipolar disorder, life experiences, and backgrounds, which often contained emotive language and humor. They regularly sought and offered advice, and expressed encouragement and empathy. The forum would have benefitted from more users to offer a greater support network with more diverse views and experiences.

Conclusions

Online forums are inexpensive to provide and may offer peer support and the opportunity for patients to share their experiences and explore issues related to their illness anonymously. Future research should focus on how to enhance patient engagement with online health care forums.

Trial Registration

ISRCTN81375447; http://www.isrctn.com/ISRCTN81375447 (Archived by WebCite at http://www.webcitation.org/6YzWtHUqu).
Retraction: Shuang-Qing L, Jiang-Ying G, Qun D, Zhong-Jie H, Shu-Hong L. Anticoagulant effect of Huisheng Oral Solution in a rat model of thrombosis. Arch biol sci. 2013;65(3):1223-31. DOI: 10.2298/ABS1303223L
Authors: Editorial E
Published: July 2015

This is a notice of retraction of the article: Anticoagulant effect of
Huisheng Oral Solution in a rat model of thrombosis, published in the
Archives of Biological Sciences in 2013, Vol. 65, Issue 3. The
Editor-in-Chief has been informed that this paper is a redundant publication
of an earlier paper: Shuang-Qing L, Jian-Ying G, Jun D, Qun D, Zhong-Jie H,
Hong-Yuan L, Shu-Hong L. Anticoagulant effect of Huisheng oral solution in a
rat model of thrombosis. Indian J Pharmacol. 2013;45(4):359-64. DOI:
10.4103/0253-7613.115018. This claim is correct and almost the entire paper
is a copy of the earlier one. After confirmation of this fact, the
Editor-in-Chief of the Archives of Biological Sciences has decided to
retract the paper immediately.

 Link to the retracted article 10.2298/ABS1303223L
Whether integrating refining and petrochemical business can provide opportunities for development of petrochemical industry in Serbia
Authors: Popovic Zoran , Soucek Ivan , Ostrovskii Nickolay , Ocic Ozren
Published: July 2015

Since the beginning of 90s of last century both the petroleum industry and
petrochemical industry have operated in difficult circumstances. In
particularly, margins of petroleum and petrochemical industry were
exacerbated during global economic crisis in 2008-2009 years. At that time,
as one option that could be the solution, the global analysts had started to
more intense investigate the benefits of Refining-Petrochemical Integration.
Shortly afterwards, more and more petroleum refineries and petrochemical
manufacturers began to see the future in this kind of operational,
managerial, marketing and commercial connection. This paper evaluates, in
particular, the achieved level of integration of refinery and petrochemical
businesses in Central and South-Eastern Europe. And specifically, the paper
identifies current capabilities and future chances of linking this kind of
integration between Serbian refining and petrochemical players. The viability
of integration between possible actors and benefits of every single
refining-petrochemical interface in Serbia depend on many factors, and
therefore each integrated system is unique and requires prior serious Cost
Benefit Analysis.
The influence of liners on the pulp inflammation
Authors: Davidovic Lado , Cuk Mirjana , Zivkovic-Sandic Marija , Grga Djurica , Zivkovic Slavoljub
Published: July 2015

Introduction. The study included application of liners and dental composites
in to cavities of six experimental animals - rabbits (Oryctolagus cuniculus).
Objective. The aim of the study was to investigate rabbit dental pulp
response to different liners. Methods. Cavity preparation for class V were
made on the maxillary central incisors and one lower incisor, while the
second lower incisor served as a control tooth. These teeth were restored
with the use of one of the following liners - Calcimol LC, ANA Liner and Fuji
II LC Improved, and Ceram-X mono dental composite. After an observation
period of five days animals were sacrificed and prepared for histological
analysis. The existence and degree of the pulp inflammation was determined by
using a light microscope. Results. Results showed that the used liners do not
cause distortion of the structure and continuity of the odontoblastic layer.
Inflammation was not registered in the control group, while in each group of
tested materials one tooth with mild signs of hyperemia was registered.
Results showed that all three tested liners demonstrated favorable effects on
the pulp of the tooth and did not lead to inflammatory reactions. Conclusion.
Histological analysis of the dental pulp of experimental animals suggests
that the liners used in this study do not compromise the integrity of the
odontoblastic layer, if it is applied over a thin layer of dentin. In each
group of tested materials one tooth with mild signs of hyperemia and
vasodilation was registered.
Splenomegaly in sarcoidosis: Frequency, treatment, prognosis and long-term follow-up
Authors: Pavlovic-Popovic Zora , Zaric Bojan , Kosjerina Zdravko , Petrovic Dragana
Published: July 2015

Introduction. The splenic involvement is common in sarcoidosis, but its real
frequency is still obscure, depending doubtless on the method of splenomegaly
detection. Splenomegaly may be accompanied with pain or anemia, leucopenia
and thrombocytopenia. Objective. The aim of this study was to investigate the
frequency of splenomegaly related to clinical characteristics of sarcoidosis
and to solve the dilemma - whether to introduce medicaments, and when to
perform splenectomy. Methods. The method of the study is a retrospective and
prospective analysis of the patients? material. Results. The study included
540 patients with sarcoidosis in a 20-year period. Of them, 26% had
splenomegaly detected by computerized tomography screening. Splenomegaly was
more frequently registered in the patients with a longer history of
sarcoidosis (38%), as compared to those with a shorter history of the disease
(23%) (p<0.05). Splenomegaly was more frequently registered in the patients
with other extrapulmonary lesions detected (33%) than in those who had no
extrapulmonary manifestations of sarcoidosis (17%) (p<0.01). Indications,
possible benefits and complications of splenectomy were analysed in 11
sarcoidosis patients undergoing this intervention for various reasons, of
which the follow-up period ranged from one to 20 years. Conclusion.
Splenomegaly was more frequent in chronic cases or in the patients with
established sarcoid lesions of other extrapulmonary organs. The primary
treatment of uncomplicated symptomatic splenic sarcoidosis includes
medicamentous therapy. Occasionally, splenectomy is required. Prognostically,
splenomegaly indicates an unfavorable course of the disease.
Adverse effects of pharmacological therapy of benign prostatic hyperplasia on sexual function in men
Authors: Stojanovic Nebojsa , Ignjatovic Ivan , Djenic Nebojsa , Bogdanovic Dragan
Published: July 2015

Introduction. The development of effective medications makes pharmacological
therapy of BPH the dominant mode of treatment today. It improves urinary
symptoms and prevents disease progression while producing side effects on
male sexual function. Objective. The aim of the study is to present the
effects of BPH pharmacological treatment on the occurrence of sexually
adverse effects in men: changes in sexual desire, erectile, ejaculatory and
the orgasmic function. Methods. A prospective study involving 156 BPH
patients. The average age was 61.16?2.97. Four groups of 39 patients each
were formed. The 4 groups were administered tamsulosin (alpha-blocker),
finasteride (5-alpha reductase inhibitor), combination therapy (tamsulosin
and finasteride) respectively, while the control group received no treatment.
IPSS-QoL, IIEF and MSHQ-EjD questionnaires were used to evaluate the symptoms
of voiding and sexual function. Follow-up examinations were performed 3 and 6
months into treatment. Results. Voiding symptoms improved in all groups
receiving therapy. The side effects on the sexual function in all these
groups include significant disorders of ejaculation and the orgasmic
function. Ejaculation disorders: tamsulosin (-4.38?2.55; p<0.001), combined
therapy (-3.89?2.84) and finasteride (-1.49?2.52). Orgasmic function
disorders: tamsulosin (-1.03?1.94), combined therapy (-0.76?2.07) and
finasteride (-0.54?1.68). Complete absence of ejaculation was experienced by
23% of patients on combined therapy, 15% on tamsulosin and 5% on finasteride.
Conclusion. Pharmacological therapy of BPH improved voiding symptoms
producing different effects on male sexual function. The main adverse effect
on sexual function in men is the deterioration in ejaculation or the absence
thereof. Clinical consideration of BPH should include the elements of male
sexual function, patients? age, the characteristics and effects of each group
of drugs.
Primary Merkel cell carcinoma of the eyelid - clinical, histopathological, immunohistochemical and electron microscopical features: A case report
Authors: Bobic-Radovanovic Anica , Latkovic Zoran , Labudovic-Borovic Milica , Rasic Dejan
Published: July 2015

Introduction. Merkel cell carcinoma (MCC) is a rare eyelid neoplasm which can
cause significant diagnostic and especially therapeutic challenges. Case
Outline. This is the first documented report of the case of primary MCC of
the eyelid in Serbia. Conclusion. The optimal therapy must be individualized
in any given patient and, early diagnosis and meticulous follow-up are
mandatory to achieve a long-term cure.
Colorectal adenocarcinoma metastasizing to the oral mucosa of the upper jaw
Authors: Baranovic Marijan , Vidakovic Bruno , Sauerborn Damir , Peric Berislav , Uljanic Ivana , Mahovne Ivana
Published: July 2015

Introduction. Metastases to the oral cavity are uncommon, accounting for only
1% of all oral malignant tumors. When they occur they mostly originate from
primary tumors of the lungs, kidney, breast and prostate. Oral metastases
from the primary colorectal carcinoma are much more infrequent. Case Outline.
We present an unusual case of a 78-year-old man with a soft tissue oral
metastasis originating from the primary colorectal carcinoma. The patient was
referred to the Department of Otorhinolaryngology, Head and Neck Surgery with
an intraoral mass on the right side of the maxilla. The diagnosis was
confirmed by histopathologic examination and immunohistochemical analysis.
Conclusion. Oral metastases occur rarely and often can mimic much more common
benign lesions, therefore they should be considered as a possibility in a
differential diagnosis.
Cardiac manifestations in antiphospholipid syndrome - a brief review of the literature
Authors: Djokovic Aleksandra , Stojanovic Ljudmila
Published: July 2015

Antiphospholipid syndrome (APS) or Hughes syndrome represents a systemic
autoimmune disorder characterized by arterial and/or venous thrombosis,
multiple and recurrent fetal losses, accompanied by persistently elevated
levels of antiphospholipid antibodies (aPL). This syndrome is considered
primary if unassociated with any other connective tissue disease, or
secondary if it appears in association with other autoimmune disorders,
mainly systemic lupus erythematosus. Cardiac manifestations in APS are
integral part of the syndrome. aPL are involved in the pathogenesis of
pseudoinfective endocarditis (Libman Sacks) and other valvular manifestations
presented as their thickening and dysfunction. Intracardiac thrombi and
myxomas, pulmonary hypertension and left ventricular dysfunction are also
distinguishing features of APS. On the other hand, accelerated
atherosclerosis, proven in APS and also aPL mediated, is accountable for the
development of coronary and peripheral artery disease. This leads to higher
cardiovascular mortality rate in the population of patients with low
incidence of the traditional atherosclerosis risk factors. Furthermore,
recent studies implied that presence of certain aPL could be a risk factor
for a specific cardiac manifestation. Bearing all this in mind, early
diagnosis of cardiac manifestations, control and abolition of traditional
risk factors, as well as close cardiac follow-up of APS patients, are crucial
in reducing their cardiovascular mortality.
Combined effect of photobiomodulation with a matrix metalloproteinase inhibitor on the rate of relapse in rats
Authors: Lee Sang-Hyun , Kim Kyung-A , Anderson Stephanie , Kang Yoon-Goo , Kim Su-Jung
Published: July 2015

Objective: 

To investigate combined effect of photobiomodulation with a matrix metalloproteinase (MMP) inhibitor on the relapse rate in relation to MMP expression in rats.

Materials and Methods: 

Fifty-two rats were divided into four groups according to the treatment modality: control group, irradiation group, doxycycline group, and irradiation with doxycycline group. During a relapse period of 5 days after orthodontic movement, maxillary central incisors were treated by low-level laser therapy (LLLT) as a photobiomodulation and/or doxycycline as a synthetic MMP inhibitor. Relapse rate was evaluated in association with MMP expression at the gene and protein levels.

Results: 

Relapse rates were increased by LLLT (1.57-fold) and decreased by doxycycline (0.83-fold) compared with the control, showing positive correlation with the levels of expression for all MMPs in the periodontal ligament (PDL). LLLT concomitant with doxycycline administration resulted in no significant differences of relapse rate and MMP expression from the control.

Conclusions: 

The combined effect of photobiomodulation with an MMP inhibitor around the relapsing teeth proved to be antagonistic to PDL remodeling activity during relapse. This study suggests a basis for developing a novel biologic procedure targeting the MMP-dependent PDL remodeling to control the relapse rate.
Allogeneic Mesenchymal Precursor Cells in Type 2 Diabetes: A Randomized, Placebo-Controlled, Dose-Escalation Safety and Tolerability Pilot Study
Authors: Skyler Jay S. , Fonseca Vivian A. , Segal Karen R. , Rosenstock Julio
Published: July 2015

OBJECTIVE

To assess the safety, tolerability, and feasibility of adult allogeneic bone marrow–derived mesenchymal precursor cells (MPCs) in type 2 diabetes inadequately controlled with metformin either alone or with one additional oral antidiabetic agent.

RESEARCH DESIGN AND METHODS

The study was a dose-escalating randomized placebo-controlled trial assessing one intravenous (IV) infusion of MPCs (rexlemestrocel-L; Mesoblast Inc.) 0.3 × 106/kg (n = 15), 1.0 × 106/kg (n = 15), or 2.0 × 106/kg (n = 15) or placebo (n = 16). Study duration was 12 weeks.

RESULTS

Subjects (21 women, 40 men) with a mean ± SD baseline HbA1c 8.3 ± 1.0% (67 ± 10.9 mmol/mol), BMI 33.5 ± 5.5 kg/m2, and diabetes duration 10.1 ± 6.0 years were enrolled at 18 U.S. sites. No acute adverse events (AEs) were associated with infusion. No serious AEs, serious hypoglycemia AEs, or discontinuations due to AEs over 12 weeks were found. No subjects developed donor-specific anti-HLA antibodies or became sensitized. The safety profile was comparable among treatment groups. Compared with placebo, a single IV infusion of rexlemestrocel-L reduced HbA1c at all time points after week 1. The adjusted least squares mean ± SE dose-related differences in HbA1c from placebo in the rexlemestrocel-L groups ranged from −0.1 ± 0.2% (−1.1 ± 2.2 mmol/mol) to −0.4 ± 0.2% (4.4 ± 2.2 mmol/mol) at 8 weeks and from 0.0 ± 0.25% to −0.3 ± 0.25% (−3.3 ± −2.7 mmol/mol) at 12 weeks (P < 0.05 for 2.0 × 106/kg dose at 8 weeks). The clinical target HbA1c <7% (53 mmol/mol) was achieved by 33% (5 of 15) of the subjects who received the 2.0 × 106/kg dose vs. 0% of those who received placebo (P < 0.05).

CONCLUSIONS

This short-term study demonstrates the safety and feasibility of up to 246 million MPCs in subjects with type 2 diabetes.
Influence of phylogeny, migration and type of diet on the presence of intestinal parasites in the faeces of European passerine birds (Passeriformes)
Authors: Bandelj Petra , Blagus Rok , Trilar Tomi , Vengust Modest , Rataj Aleksandra Vergles
Published: July 2015

Migratory and non‐migratory passerine birds can carry several pathogens, including parasites, which may cause significant diseases in birds, other animal species and humans. Parasites have been shown to negatively impact many populations of wildlife, and this may become more significant with global temperature changes. This study was performed to investigate the prevalence of intestinal parasites in faecal samples of European passerines. Intestinal parasites identified were statistically associated with passerines phylogenetic classification, migratory habits (migratory, non‐migratory) and the type of diet (omnivorous, insectivorous and granivorous). A total of 385 passerines of 42 species were captured and their droppings collected. The prevalence of parasites in faecal samples of passerines was 15.6%. Intestinal parasites were identified in 50/309 (16.2%) migratory passerines and 10/76 (13.2%) non‐migratory passerines using the faecal flotation method. Coccidia were most often identified parasites; they were more likely to be present in an omnivorous bird species (p = 0.02). Syngamus spp. was more likely to be detected in omnivorous passerines (p = 0.04). Tits (p = 0.01) and finches (p = 0.006) were less likely to have intestinal parasites present in their faecal samples than passerines classified in other phylogenetic clades. Tits (p = 0.02) and finches (p = 0.008) were also less likely to have coccidia present in their faecal samples. Phylogeny was associated with the presence of parasites in faecal samples of passerines (p = 0.03). The prevalence of parasites, however, was not associated with the migration habit of passerines, but to the type of diet (p = 0.04). Our analysis suggests that the diversity of feeding sources of omnivore passerines exposes them to infection with intestinal parasites to a greater extent than granivore or insectivore passerines.