bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative study of the difficulty of endotracheal intubation in sniffing and 25-degree backup positions
Authors: Ibrahem G.
Published: April 2024

Introduction. The endotracheal intubation procedure is integral to modern medicine and essential to emergency care, surgical practice and intensive care procedures.

The objective was to evaluate the effect of the 25° backup position on glottic view and difficulty of intubation compared to the sniffing position in adult patients receiving general anaesthesia with endotracheal intubation

Materials and methods. The comparative clinical study was conducted in Al-Hussain Military Hospital, Baghdad, Iraq during the period from 1st of January 2022 to 1st of January 2023. A convenient sample of 150 patients who aged 18–60 years, were classified according to the American Society of Anesthesiologists as I or II, and underwent elective surgery under general anaesthesia was included in this study. These patients were allocated into two groups. Group A consisted of 75 patients who were anaesthetized in the sniffing position. Group B consisted of 75 patients who were anaesthetized in 25° backup position.

Results. There was no significant difference between the sniffing position and 25° backup position regarding the number of patients who needed ancillary manoeuvres and ancillary equipment (P-values were 0.583 and 0.151, respectively). The glottic view was significantly better in the 25° backup position than the sniffing position according to the Cormack–Lehane (p = 0.001) with a significantly lower difficulty in intubation according to the intubation difficulty scale (p = 0.008).

Conclusion. The 25° backup position is better than the sniffing position in glottic visualization, the difficulty of intubation and the time of intubation. Age, gender, and body mass index have no significant effects on the visualization of the glottis between the 25° backup position and the sniffing position. There was no significant difference between two regarding the number of patients who needed ancillary manoeuvres and ancillary equipment. The glottic view is significantly better in the 25° backup position than sniffing position according to the Cormack–Lehane. The mean of the time of intubation is lower in the 25° backup position compared to the sniffing position.
The effectiveness of dexmedetomidine cardioprotection during vascular surgery in high cardiac risk patients
Authors: Kozlov I. A. , Sokolov D. A. , Lyuboshevsky P. A.
Published: April 2024

The objective was to study the occurrence of perioperative cardiovascular complications (CVС) and clinical and laboratory cardioprotection parameters in patients treated with dexmedetomidine infusion in perioperative period of vascular surgery.

Materials and methods. The study involved 204 patients with high cardiac risk (revised cardiac risk index > 2, risk of perioperative myocardial infarction or cardiac arrest > 1%) who underwent elective vascular surgery. The patients were randomly divided into two groups. Group I patients received perioperative infusion of dexmedetomidine at a dose 0.40 [0.34–0.47] mg/kg/h during 7.0 [6.0–8.0]) hours. Group II was a control group. In the perioperative period, the occurrence of CVC, the blood level of the N-terminal fragment of the prohormone B-type natriuretic peptide (NT-proBNP) and cardiospecific troponin I (cTnI) were analyzed. The data were statistically processed, using the Fisher’s exact test, Mann–Whitney test and logistic regression.

Results. Perioperative CVC without taking into account arterial hypotension were recorded in 3 (2.9%) patients in group I and in 14 (13.7%) patients in group II (p = 0.009). Arterial hypotension was recorded in 14 (13.7%) patients in group I and in 5 (4.9%) patients in group II (p = 0.051). Perioperative dexmedetomidine infusion reduced the risk of CVC, except for arterial hypotension (OR 0.1905, 95% CI 0.0530–0.6848, p = 0.011) and increased the risk of arterial hypotension (OR 3.5787, 95% CI 1.1254–11.3796, p = 0.031). The cTnI level in patients of groups I and II was 0.017 [0.011–0.024] and 0.019 [0.011–0.028] ng/ml (p = 0.196) before surgery, 0.02 [0.011–0.029] and 0.02 [0.015–0.039] ng/ml (p = 0.050) after surgery, 0.018 [0.014–0.024] and 0.028 [0.018–0.033] ng/ml (p = 0.0002) before discharge from the hospital. At the same stages, the level of NT-proBNP was 221.5 [193.3–306.5] and 237.8 [171.3–310.1] pg/ml (p = 0.572), 237.0 [205–303.5] and 289.0 [217.5–409.5] pg/ml (p = 0.007), 250.5 [198.8–302.0] and 259.6 [171.0–421.6] pg/ml (p = 0.933).

Conclusion. In patients at high cardiac risk undergoing vascular surgery, perioperative dexmedetomidine infusion reduces the risk of a composite outcome including cardiac mortality, nonfatal myocardial infarction, myocardial ischemia, pulmonary embolism, stroke, hypertension, and arrhythmias, while the risk of arterial hypotension increases significantly. The perioperative dynamics of cTnI and NT-proBNP require further research. The start of dexmedetomidine infusion in 2.7% of cases is accompanied by severe bradycardia, requiring discontinuation of the infusion.
Corrosion of austenitic Fe-Ni based alloys with various chromium and aluminum additions in a carburizing-oxidizing atmosphere at 800ᵒC
Authors: Liu Shu , Zhu Yong , Cao JunJie
Published: April 2024

The corrosion behaviors of Fe-19Ni-13/21Cr-xAl (x = 0, 2, 6 at. %) alloys in a carburizing-oxidizing atmosphere were compared with those in a purely carburizing atmosphere at 800oC. For alloys with 13 at. % Cr, 2 at. % addition of Al did not improve the corrosion resistance effectively but induced a slightly increase of the total mass gain. 6 at. % addition of Al produced a large decrease of the total mass gain, therefore the corrosion resistance was improved significantly. For alloys with 21 at. % Cr, additions of Al did not affect the total mass gain obviously. Fe-19Ni-21Cr-xAl (x = 0, 2, 6 at. %) showed similar mass gain. Increase of Cr content from 13 at. % to 21 at. % is effective for protecting the alloys from the carbon attack for Al-free alloys and alloys with 2 at. % Al. However, addition of Cr is not so helpful for alloys with 6 at. % Al. The addition of oxygen improved the corrosion resistance of all alloys significantly except the Fe-19Ni-13Cr-6Al. Pure external chromia scales on alloys without Al and with 2 at. % Al could not suppress the inward diffusion of the carbon atoms. Aluminum and chromium worked together to form mixed oxide scales inhibiting the carbon attack totally on alloys with 6 at.% Al.
Linguística y significación
Authors: Baena Z. Luis Angel
Published: April 2024

Resumen
Mesh-Agnostic Decoders for Supercritical Airfoil Prediction and Inverse Design
Authors: Li Runze , Zhang Yufei , Chen Haixin
Published: April 2024

Mesh-agnostic models have advantages in terms of processing unstructured spatial data and incorporating partial differential equations. Recently, they have been widely studied for constructing physics-informed neural networks, but they need to be trained on a case-by-case basis and require long training times. On the other hand, fast prediction and design tools are desired for aerodynamic shape designs, and data-driven mesh-based models have achieved great performance. Therefore, this paper proposes a data-driven mesh-agnostic decoder that combines the fast prediction ability of data-driven models and the flexibility of mesh-agnostic models. The model is denoted by an implicit decoder, which consists of two subnetworks, i.e., ShapeNet and HyperNet. ShapeNet is based on implicit neural representation, and HyperNet is a simple neural network. The implicit decoder is trained for the fast prediction of supercritical airfoils. Different activation functions are compared, and a spatial constraint is proposed to improve the interpretability and generalization ability of the model. Then, the implicit decoder is used together with a mesh-based encoder to build a generative model, which is used for the inverse design of supercritical airfoils with specified physical features.
Dem „Mahlstrom des Vergessens entzogen“. Der Bestand des Staatsarchivs Oppeln als Forschungsquelle für Germanisten
Authors: Blach-Margos Małgorzata
Published: April 2024

Zwischen den Antonymen ‚Erinnern‘ und ‚Vergessen‘ gibt es nach Aleida Assmann (2016) eine Zwischenstufe, die sie als ‚Verwahrensvergessen‘ bezeichnet und mit dem Eintritt ins Archiv gleichsetzt. In Archiven werden Unterlagen verwahrt, die Antworten auf künftig gestellte Fragen geben oder ein neues Licht auf die Vergangenheit werfen können. Da im Oppelner Staatsarchiv ca. fünf Kilometer Schriftgut in deutscher Sprache aufbewahrt wird, soll der folgende Beitrag Wissenschaftler, vor allem Germanisten, zurQuellenforschung anregen.
Kanzleisprachliche Syntax in mittelalterlichen Breslauer Ratsbüchern
Authors: Smereka Joanna
Published: April 2024

Im vorliegenden Beitrag werden Breslauer Ratsprotokolle aus den Jahren 1451 und 1501 in Bezug auf die Syntax untersucht. Die Ergebnisse der am handschriftlichen Sprachmaterial durchgeführten Analysen werden mit Untersuchungen zur frühneuhochdeutschen Syntax verglichen. Ausgehend von der These, dass syntaktische Entwicklungen in den Kanzleisprachen einen besonderen Einfluss auf die Herausbildung des heutigen Deutsch hatten, wird nach der Modernität der Syntax in den Breslauer Ratsbüchern gefragt. Die syntaktische Formelhaftigkeit der Eintragungen in den Stadtbüchern hatte jedoch – wie es sich bei derUntersuchung herausgestellt hat – Einfluss auf die verspätete Umsetzung der als modern angesehenen Muster in diesen Texten.
Transforming medical education in the 21st century: the role of competency-based medical education
Authors:   Universidad Privada del Norte, Ramos Zaga Fernando
Published: April 2024

Introduction: With the changing landscape of medical education, it is crucial to critically examine existing approaches and frameworks. competency-based medical education (CBME) emerges as a promising paradigm shift, which prioritizes learner-centered, outcome-oriented development of skills, knowledge, and attitudes. Objective: To identify the essential structural and procedural adjustments needed for effective implementation of CBME. It underscores the importance of reorganizing educational institutions, adapting instructional and assessment techniques, and fostering acceptance of CBME in the classroom. Results: To effectively deliver CBME, it is imperative to restructure educational institutions to focus on competency-based curricula and personalized instruction. Also, there is a need to modify teaching and assessment strategies to facilitate continuous assessment and active learning. Conclusions: Adopting CBME principles can enable medical education to produce professionals equipped with the skills necessary to meet the dynamic demands of modern medicine.
Correlation of histopathological results and tomographic findings in patients with liver lesions suspicious for malignancy
Authors:   Centro Médico Nacional “Gral. de Div. Manuel Ávila Camacho”, Valencia Montiel Luis P. , Hernández Santos Jorge R. ,   Centro Médico Nacional “Gral. de Div. Manuel Ávila Camacho”, García-Galicia Arturo ,   Centro Médico Nacional “Gral. de Div. Manuel Ávila Camacho”, Montiel-Jarquín Álvaro J. ,   Centro Médico Nacional “Gral. de Div. Manuel Ávila Camacho”, López García Diana ,   Centro Médico Nacional “Gral. de Div. Manuel Ávila Camacho”, Tapia Venancio Maricarmen ,   Centro Médico Nacional “Gral. de Div. Manuel Ávila Camacho”, Bertado-Ramírez Nancy R. ,   Centro Médico Nacional “Gral. de Div. Manuel Ávila Camacho”
Published: April 2024

Introduction. Liver cancer is the seventh most common neoplasm worldwide and the second cause of mortality directly associated with cancer. In Mexico it has an incidence of 3.9% in the entire population. Although computed tomography (CT) is the imaging study of choice, the final diagnosis is established with the anatomopathological study of the lesion. Objective. Correlate the tomographic findings with the histopathological result in patients with liver lesions with suspicion of malignancy, who underwent USG-guided biopsy. Methods. Descriptive, correlation, retrolective, homodemographic and single-center study. The study period was from September 2021 to February 2022. Patients older than 18 years with liver lesions suspicious of malignancy were selected and underwent Computed Axial Tomography and ultrasound-guided biopsy. Shapiro Wilk tests (for normality) were used and chi-square was used for an analysis of association of categorical variables. Results. Twenty-four patients were included, who underwent Tomography and lesion biopsy, finding an average size of lesions of 2.39cm. The results of the correlation between the tomographic diagnosis and the definitive histopathological diagnosis did not have statistical significance p=0.069. Conclusion. No significant correlation was found between the histopathological study and tomographic findings in liver lesions suggestive of malignancy.
Non-Fatal strangulation/suffocation in context of gender violence: Medicolegal aspects and implications in clinical practice
Authors:   Universidad de La Frontera, Núñez Garrido Mónica A. , Herrera Umanzor Sergio ,   Universidad de La Frontera
Published: April 2024

Despite the numerous efforts of the international community to eradicate all forms of violence against women, this problem is far from being resolved. According to the UN, one in three women has suffered physical or sexual violence from an intimate partner, sexual violence outside the couple, or both at least once in their life. Addressing this problem as a social health need of population groups allows an approach to gender violence as a collective health problem. At the level of physical violence, strangulation/suffocation has been identified as one of the most lethal forms of domestic violence and sexual assault. Victims of domestic violence who have been choked or strangled are 7.5 times more likely to be killed by their partner. A victim of strangulation/suffocation can lose consciousness in seconds or die within minutes, days or weeks after the attack, as well as suffer permanent brain damage or disability or emotional trauma. Recently, legal changes have been generated in the configuration of this crime, the penalties have increased in United Kingdom, the United States, Australia and New Zealand. The current non-systematic narrative review of literature sought to explore updated medico-legal aspects of non-fatal strangulation/suffocation in the context of gender violence, and are highlightedrelevant implications for clinical practice.
Vitamins B1, B6, and B12 and Peripheral Neuropathies: International expert consensus
Authors:   Instituto de Investigación en Ciencias Biomédicas, Longa López John CM. , Dinamarca-Montecinos José L. ,   Universidad de Valparaíso, Mejía-Rojas Koni ,   Hospital Nacional Daniel Alcides Carrion, Bernaola Cuadro Astrid C. ,   Sociedad de Medicina de Rehabilitación del Perú y de la Asociación Médica Latinoamericana de Rehabilitación, Ampuero Bárcena Jessica B. ,   Clínica del Adulto, Palacios-Sánchez Leonardo ,   Centro de Neurociencia “Neurovitae”, Fernandez-Fairen Mariano ,   Universidad Internacional de Cataluña
Published: April 2024

Based on a bibliographic review of the literature, a consensus of international experts has been carried out on the use of vitamins B1, B6, B12, in their deficiencies, and in the peripheral neuropathy that may be associated with them, to optimize the management of these conditions. Several questions considered important and worthy of being addressed and clarified were raised, retaining nine of them for further discussion to achieve consensus. Forty one recommendations on the management of these conditions have been proposed, with unanimity of the participants in the consensus. This has been an attempt to clarify controversial points, assisting the clinician's attitude in current medical practice.
Tratamento da obesidade com a liraglutida e suas principais manifestações clínicas
Authors: Dos Santos Leonardo Miranda , Rocha Caio Viñé , E Silva Demetrius de Souza , De Brito Victoria Duarte Barros , Albuquerque Yasmin de Sousa , Barros Mariana Tenório Cavalcante Duarte de , Da Silva Anderson Felipe Bezerra , Lima Letícia Laís Ribeiro de , Resquim Fabrizio Daniel Mendonça , Leite Cleber Queiroz
Published: April 2024

Objetivo: Identificar os aspectos gerais do tratamento da obesidade através do uso da liraglutida e as suas principais manifestações clínicas com a atualização do tema na literatura nacional. Revisão bibliográfica: O efeito resultante da prescrição de liraglutida para o tratamento da obesidade funciona através do precursor metabólico de um agonista do receptor do peptídeo 1 semelhante ao glucagon (GLP-1), o que significa que imita a ação de um hormônio natural chamado GLP-1. O GLP-1 ajuda a regular os níveis de açúcar no sangue, aumentando a secreção de insulina, reduzindo a produção de glucagon e retardando o esvaziamento gástrico. As manifestações clínicas evoluem com reações adversas gastrointestinais transitórias, incluindo náusea, vômito e diarreia. Outrossim, há na literatura outras manifestações apresentadas, como colelitíase e colecistite, bem como doenças da tireóide e aumento da frequência cardíaca. Considerações finais: As manifestações clínicas decorrentes do uso da liraglutida para o tratamento da obesidade são relativamente raras, porém muito subdiagnosticadas. Tratando-se de condições clínicas de extrema importância, principalmente, pelo reconhecimento das alterações metabólicas, devendo ser reconhecidas pelos profissionais da saúde. O diagnóstico precoce das manifestações clínicas e um tratamento eficaz evita as lesões de diversos órgãos, diminuindo a nocividade do medicamento no tratamento da obesidade.
Rights of data subjects in the processing and use of personal information by automated decision-making systems
Authors: Bolotayeva O. S.
Published: April 2024

The modern technological development of society poses new challenges to legal science, the federal industry base for regulating the newly united broad relations. Despite the undeniable benefits and benefits that a person receives in connection with the use of digital technologies, there are many different risks and risks, including objects that occupy a central place occupied by human rights. The vulnerability of the rights and legitimate interests of people, including in connection with the processing and use of their personal information, requires the adoption of a number of restrictions and rules designed to prevent possible adverse consequences of a personal and property nature. The article considers the conceptual provisions on the use of automated decision-making systems with respect for the rights and legitimate interests of data subjects, reflected in the documents of the European Union, conclusions and proposals are made regarding the application of a risk-based approach in the legal regulation of relations related to the use of such systems.
Development of the legal framework for the functioning regional parliaments in modern Russia
Authors: Grigoriev N. A. , Zakharov A. N.
Published: April 2024

This paper considers the issue of the evolution of the regulatory framework for the functioning of regional parliaments in the modern history of the Russian Federation. Regional legislative assemblies (legislatures) are an important political institution in the development of Russian federalism. The problem of the formation of regional legislative assemblies and the definition of a clear regulatory framework for functioning are noted. The materials of the article are based on the study of regulations that implement the provisions of the federal law of October 6, 1999, Federal Law No. 184 “On the general principles for the implementation of legislative and executive bodies of state power of the constituent entities of the Russian Federation.”
The effectiveness of criminal law norms with administrative prejudice: the essence and signs
Authors: Laktyukhin A. О.
Published: April 2024

The adoption of any legal norms pursues certain goals. This rule also applies to criminal law norms with administrative prejudice. The achievement of such goals in conjunction with compliance with the general principles of legal regulation ensures the necessary effect. At the same time, criminal law science has not developed a unified concept of interpretation of the essence of the effectiveness of criminal law norms with administrative prejudice. In this regard, the article aims to determine the essence of their effectiveness, as well as the main features of this category as features of some norms. To achieve this goal, existing approaches to the interpretation of the effectiveness of legal norms were analyzed, in general, signs of effectiveness as features of the rule of law were identified. The latter were correlated with signs of criminal law norms with administrative prejudice to establish the true essence of their effectiveness.
Professors as people who bring light to the masses
Authors: Kim-Kimen A. N.
Published: April 2024

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The role of M. E. Nikolaev in the development of the Sakha Republic (Yakutia) and the Russian federal statehood
Authors: Kim-Kimen A. N. , Ilyina A. A. , Samsonova S. S.
Published: April 2024

The article examines the role of Mikhail Nikolaev,the first President of the Sakha Republic (Yakutia), in the development of our republic and country, during the period of global changes in the life of society. The authors of the article consider various aspects of the multifaceted activities of the recognized leader of our people, thanks to which our republic occupies its rightful place among 89 subjects of the Russian Federation. The relevance of the article lies in the fact that due to the strategic course determined by Nikolaev and implemented by the successors of his cause, the popularly elected leaders of the SR(Y) V. A. Shtyrov, E. A. Borisov and A. S. Nikolaev, our republic has made and continues to make its worthy contribution to the development of Russian federalism and strengthening the unity of our multinational and multi-confessional Homeland, during the period when we celebrate the 30th anniversary of the Constitution of the Russian Federation and will participate in the next eighth presidential elections of the Russian Federation in March 2024, and also began active preparations for the 400th anniversary of Yakutia’s entry into the Russian state, which will be celebrated in 2032. The aim of the research is to create an image of a true leader who can inspire and become a role model for current and future generations of activists, public figures and politicians at the regional and federal levels. The objectives of the study are to determine the effectiveness of regulatory regulation in order to achieve high results in government activities. The authors conclude that today the ideas and initiatives implemented in the regulatory decisions of the first President of Yakutia M. E. Nikolaev are successfully implemented in the region and, moreover, are scaled to the federal level and are highly appreciated in the world community.
Review of the All-Russian Scientific and Practical Conference of the Institute of State and Law of the Russian Academy of Sciences and North-Eastern Federal University «Relevant issues of Private Law» dedicated to the 30th anniversary of the adoption by popular vote of the Constitution of Russia
Authors: Koryakina Z. I.
Published: April 2024

The article provides a review analysis of the All-Russian scientific and practical conference “Current problems of private law”, dedicated to the 30th anniversary of the Constitution of Russia, which took place within the walls of the Institute of State and Law of the Russian Academy of Sciences (Moscow), Faculty of Law, M. K. AmmosovNorth-Eastern Federal University in Yakutsk, December 07-08, 2023.
Issues of ethnic and cultural identity in the Sakha Republic (Yakutia)
Authors: Koryakin K. D. , Vasiliev K. E.
Published: April 2024

Ethnic and cultural identity plays an important role in shaping people’s consciousness and selfawareness. This topic becomes especially relevant in multinational regions where different ethnic groups live side by side and coexist on the same territory. One of these regions is the Sakha Republic (Yakutia), where different ethnic groups coexist and interact, each of which retains its unique national and cultural identity.
Ethics and law in the regulation of artificial intelligence
Authors: Bolotaeva О. S.
Published: April 2024

While improving the quality of life, digital technologies, which are developing rapidly and covering more and more social spheres, also carry potential threats, including to the rights and interests of people, organizations, and the state. The development of methods and forms of communication contributes to the emergence of new ethical problems, but the greatest concern is the development of artificial intelligence technologies, which can replace human intellectual work and ensure autonomous decisionmaking, including without human control. The latter circumstance is a serious reason for discussing the ethics of artificial intelligence and the legal regulation of relations related to the use of such technologies.
Optimization of Superchilling Liquid Formula and Solutions for Storage of Duck Meat
Authors:   Anhui Institute of Product Quality Supervision and Inspection, Hefei, P.R. China, P-X Lou , T-T Li ,   Anhui Institute of Quality and Standardization, Hefei, P.R. China
Published: April 2024

In order to optimize the proportion of materials in the superchiling solution, a freezing temperature superchiling solution was designed to meet the requirements of storage of duck meat. Response surface analysis (RSM) method was used to investigate the effect of salt and alcohol on the change of freezing point. The CCD response surface model was used to determine the optimum conditions and the optimal ratio was obtained. The results showed that the optimum design conditions were 6 % Cacl2 and 3% 1,2-Propanediol The freezing point temperature is -5.21°C. And optimizing the sorbitol solution, the ascorbic acid solution, and the chitosan solution with different mass ratios based on obtaining the optimal proportion of the micro-freezing liquid. The results showed that 2% sorbitol, 0.3% ascorbic acid and 0.6% chitosan were good in duck meat quality.
Efficacy of Edible Coating Based on the Rice Bran Oil and Acetylated Potato Starch Carrier Natamycin on the Qualitative Properties of Grape
Authors:   Department of Food Science and Technology, Ferdowsi University of Mashhad (FUM), Mashhad, Iran, AO Jeivan , M Taghizadeh ,   Department of Food Science and Technology, Ferdowsi University of Mashhad (FUM), Mashhad, Iran, M Yavarmanesh ,   Department of Food Science and Technology, Ferdowsi University of Mashhad (FUM), Mashhad, Iran
Published: April 2024

Use of agricultural products and their wastes have provided edible coatings and films, which have been more developed in recent years. This type of the food storage system, especially for fruits has well increased the product’s shelf life greatly and has reduced wastes. Emulsion gel consisting 6.57 gr of the acetylated potato starch and 2 gr of the rice bran oil produced at 7 rpm homogenization rate was selected as the best combination of edible coating. Edible coating consisting the rice bran oil and acetylated potato starch (control) increased acidity but reduced pH and TSS during storage. Addition of the high concentrations (10 and 20 mg L-1) of the natamycin caused the reduction of spoilage agent, waste and weight loss of clusters; also, it caused to more brightness of the clusters and reduced pH and acidity during storage; however, TSS was increased.
Ovarian Sertoli Cell Tumor and its Association with Infertility in a Patient with Peutz–Jeghers Syndrome
Authors:   University Clinic of Gynecology and Obstetrics, Medical faculty, Skopje, R North Macedonia, Vesna Antovska , Borivoje Pavlovski ,   University Clinic of Gynecology and Obstetrics, Medical faculty, Skopje, R North Macedonia, Eva Sozovska ,   University Clinic of Gynecology and Obstetrics, Medical faculty, Skopje, R North Macedonia, Siandra Sejfullai ,   University Clinic of Gynecology and Obstetrics, Medical faculty, Skopje, R North Macedonia, Rubens Jovanovich ,   Institute of Pathology, Medical Faculty, Skopje, R North Macedonia
Published: April 2024

We present a case of a 39-year-old woman whose primary concern was infertility, for which she came to the University Clinic for Gynecology and Obstetrics, Medical Faculty, Skopje, seeking further evaluation. On routine ultrasound, a solid tumor of the right ovary was visualized. She had been previously diagnosed with Peutz–Jeghers syndrome. She underwent a right salpingo-oophorectomy, and the final histopathological diagnosis revealed a well-differentiated Sertoli cell tumor of the right ovary.
Mitotically Active Cellular Fibroma of the Ovary: A Case Report
Authors:   Department of Gynecology and Obstetrics, University of Clinical Gynecology and Obstetrics, Macedonia, Antovska Vesna , Belchovska Eva Sozovska ,   Department of Gynecology and Obstetrics, University of Clinical Gynecology and Obstetrics, Macedonia, Gjoreska Iva Malahova ,   Department of Gynecology and Obstetrics, University of Clinical Gynecology and Obstetrics, Macedonia, Chipurovska Angela ,   Department of Gynecology and Obstetrics, University of Clinical Gynecology and Obstetrics, Macedonia, Dimovska Ivona ,   Department of Gynecology and Obstetrics, University of Clinical Gynecology and Obstetrics, Macedonia
Published: April 2024

Ovarian fibromas are benign sex cord stromal tumors composed of fibroblastic cells within a collagenous stroma. Fibromas are composed of spindled, ovoid to round cells and collagenous stroma. There are three types of benign fibromas: Fibroma with minor sex cord elements, cellular fibroma and mitotically active cellular fibroma. Fibromas are most common ovarian stromal tumors and encompasses approximately 4% of all ovarian tumors. Cellular fibromas represent approximately 10% of all ovarian fibromas. According to published studies median age of patients with ovarian fibroma is 48 years and are uncommon before 30. The potential of mitotically active cellular fibromas for reccurence and malignant transformation is low (approximately 1%) but possible. So, diagnosis od MACF is important in order to avoid misdiagnosis with ovarian fibrosarcomas and to avoid unnecessary overtreatment. Also, because of low but possible malignant potential in case of MACF, long term follow-up should be recommended. We report a case of mitotically active cellular fibroma in a 68 year old woman with previous vaginal hysterectomy without adnexectomy who applied to our clinic with mild pelvic pain and discomfort. Our intention is to point out its rarity among ovarian tumors and need for long term follow-up, because of its low but possible potential for reccurence and malignant transformation.
Latent Fingerprint Development by Brick Powder
Authors:   Applied Forensic Research Sciences, Indore, India, Mia Rakesh , Panchal Vijay ,   Applied Forensic Research Sciences, Indore, India, Dangi Preeti ,   Depertment of Forensic Science, Government Holkar Science College, India, Kamle Chanchal ,   Depertment of Forensic Science, Government Holkar Science College, India, Tripathi Asutosh ,   HOD, Institute of Sciences, Department of Forensic Science, SAGE University, India
Published: April 2024

In forensic investigations, the relationship between the criminal, the victim, and the crime scene can be firmly established through the detection of latent finger marks. Fingerprints are avital and unique identity of a person. These are impressions left by the friction ridges of a human finger on contact with any surface. Many unique characteristics in the human body like a fingerprint, DNA, palm prints, iris patterns, voices, etc. So, Fingerprint is a unique characteristic of the human body, and every human’s different fingerprints between identical twins. As we know friction ridges develop in a 3-4 month of gestation duration time. Mayer, a German doctor, and anatomist were the first to write that friction ridge skin is unique. The fingerprint is the most important evidence at the Crime scene and identification of the criminal. Fingerprint identification is a method of identification using the impression formed by the minute ridges seen on the fingertips. Fingerprint has certain individual characteristics that are unique. Latent fingerprints are most generally seen prints from the crime scene. Such prints are obtained when natural oils and perspiration existing between the fingertip ridges are transferred to a surface by any contact. Latent prints are invisible and are much harder to detect and preserve. In this research paper, a new method for the development of Latent fingerprints is used that’s brick powder. The brick powder is used in various Porous and Non-porous surfaces like plastic glass, ordinary mirror, matchbox, painted wall, writable CD, wooden substrate, currency note, door handle, floor surface, book cover, sunglasses, and mobile glass card for development of latent fingerprint impression.
Information and Cyber Security in Digitally Transformed E-Commerce Landscapes in 21st Century: An Overview
Authors:   Department of User Studies, University Library, Bayero University, Nigeria, Adakawa Murtala Ismail
Published: April 2024

The current paper aims at reviewing information security and cybersecurity in digitally transformed e-commerce landscapes. COVID-19 pandemic has led to the disruption of technology and met several businesses unprepared to take off technological transformation consequently, jeopardized many clients into untold hardships and loss. The lockdown period has changed the way people transact their businesses from physical to online mood. More recently, India has been placed on 8th position in terms of e-commerce. This requires protection of network and Apps used in communicating and transacting businesses. Students of commerce and other related programs should be encouraged to take interest in this regard for the continued development and progress of the country in particular and world in general. Governments, organizations, and societies need to security budgetary allocations for tackling the issues of cybersecurity squarely. Several issues have been discussed to justify the claim raised in the paper.
Foot Posture after MS and Functional Consequences
Authors:   Department of Mechanical Engineering, Islamic Azad University – Ilam Branch, Ilam, Iran, Taheri Alireza , Forghany Saeed ,   Department of Mechanical Engineering, Islamic Azad University – Ilam Branch, Ilam, Iran, Shaygannejad Vahid ,   Department of Mechanical Engineering, Islamic Azad University – Ilam Branch, Ilam, Iran, Kamali Mostafa ,   Department of Mechanical Engineering, Islamic Azad University – Ilam Branch, Ilam, Iran
Published: April 2024

Background: Clinical convention suggests that foot posture and movements are adversely affected by MS and cause walking difficulties but there is little objective data to support or refute these beliefs. This study explores static foot posture in people with MS and their relationship to walking disability and limitations Materials and Methods: This is a cross-sectional study that was conducted in the multiple scoliosis specialist department of Kashani Hospital in Isfahan on 44 patients with MS with mobility limitations. The indices for determining Foot Posture Index (FPI), demographic characteristics, Expanded Disability Status Scale (EDSS), and walking scale (msws-12) were investigated. Results: About one-third of participants had abnormal foot posture, which wasn’t associated with walking limitations. Most (80%) had a symmetrical foot posture with similar frequencies of supination (9%) and pronation (11/5%) abnormalities. There was no relationship between foot posture and walking limitation and expanding disability. Conclusions: A minority of people with MS had abnormal or asymmetrical foot posture and equal numbers suffered pronation and supination abnormalities; these findings challenge the beliefs that underpin the clinical management of MS-related foot problems.
Diversity-driven, efficient exploration of a MOF design space to optimize MOF properties: application to NH3 adsorption
Authors: Liu Tsung-Wei , Nguyen Quan , Bousso Dieng Adji , Gomez-Gualdron Diego
Published: April 2024

Metal-organic frameworks (MOFs) promise to engender technology-enabling properties for numerous applications. However, one significant challenge in MOF development is their overwhelmingly large design space, which is intractable to fully explore even computationally. To find diverse optimal MOF designs without exploring the full design space, we develop Vendi Bayesian optimization (VBO), a new algorithm that combines traditional Bayesian optimization with the Vendi Score, a recently introduced interpretable diversity measure. Both Bayesian optimization and the Vendi Score require a kernel similarity function, we therefore also introduce a novel similarity function in the space of MOFs that accounts for both chemical and structural features. This new similarity metric enables VBO to find optimal MOFs with properties that may depend on both chemistry and structure. We statistically assessed VBO by its ability to optimize three NH3-adsorption dependent performance metrics that depend, to different degrees, on MOF chemistry and structure. With ten simulated campaigns done for each metric, VBO consistently outperformed random search to find high-performing designs within a 1,000-MOF subset for i) NH3 storage, ii) NH3 removal from membrane plasma reactors, and iii) NH3 capture from air. Then, with one campaign dedicated to finding optimal MOFs for NH3 storage in a “hybrid” ~10,000-MOF database, we identify twelve extant and eight hypothesized MOF designs with potentially record-breaking working capacity ∆NNH3 between 300 K and 400 K at 1 bar. Specifically, the best MOF designs are predicted to i) achieve ∆NNH3 values between 23.6 and 29.3 mmol/gm, potentially surpassing those that MOFs previously experimentally tested for NH3 adsorption would have at the proposed operation conditions, ii) be thermally stable at the operation conditions and iii) require only ca. 10% of the energy content in NH3 to release the stored molecule from the MOF. Finally, the analysis of the generated simulation data during the search indicates that a pore size of around 10 Å, a heat of adsorption around 33 kJ/mol, and the presence of Ca could be part of MOF design rules that could help optimize NH3 working capacity at the proposed operation conditions
Introductory Information about Quantum Dots and their Applications
Authors: Yang Brady , Valdiviezo Jesus
Published: April 2024

Quantum dots (QDs), a type of nanoparticles, have displayed promising applications within many scientific fields. A QD is a nanoscale semiconductor particle with unique quantum mechanical properties. These tiny structures, typically ranging from 1 to 10 nanometers in diameter, exhibit distinct electronic and optical behaviors due to their size-dependent quantum confinement effects. Their applications improve upon quality, energy consumption, and efficiency in LEDs, batteries, catalysts, solar energy, and more. This review article goes over the fundamentals of nanochemistry as a whole, before proceeding into more in-depth procedures on synthesizing quantum dots and delving into various applications today. The key points of this article are to introduce scholars who are new to the field of quantum dots in the fundamentals of quantum chemistry before elaborating on the improvements quantum dots have brought to many fields. This article covers in-depth enough to grasp most concepts behind these applications, but as a whole, this field is still relatively new, in which case new applications and improvements of quantum dots can be found. In the future, quantum dots may become a key to advancing society, with possible applications in medicinal processes, more efficient energy storage, better energy generation, and quantum computing, in addition to what QDs already improved within those fields.
A Mitochondrial-Targeted Activity-Based Sensing Probe for Ratiometric Imaging of Formaldehyde Reveals Key Regulators of the Mitochondrial One-Carbon Pool
Authors: Tenney Logan , Pham Vanha , Brewer Thomas , Chang Christopher
Published: April 2024

Formaldehyde (FA) is both a highly reactive environmental genotoxin and an endogenously produced metabolite that functions as a signaling molecule and one-carbon (1C) store to regulate 1C metabolism and epigenetics in the cell. Owing to its signal-stress duality, cells have evolved multiple clearance mechanisms to maintain FA homeostasis, acting to avoid the established genotoxicity of FA while also redirecting FA-derived carbon units into the biosynthesis of essential nucleobases and amino acids. The highly compartmentalized nature of FA exposure, production, and regulation motivates the development of chemical tools that enable monitoring of transient FA fluxes with subcellular resolution. Here we report a mitochondrial-targeted, activity-based sensing probe for ratiometric FA detection, MitoRFAP-2, and apply this reagent to monitor endogenous mitochondrial sources and sinks of this 1C unit. We establish the utility of subcellular localization by showing that MitoRFAP-2 is sensitive enough to detect changes in mitochondrial FA pools with genetic and pharmacological modulation of enzymes involved in 1C and amino acid metabolism, including the pervasive, less active genetic mutant aldehyde dehydrogenase 2*2 (ALDH2*2), where previous, non-targeted versions of FA sensors are not. Finally, we used MitoRFAP-2 to comparatively profile basal levels of FA across a panel of breast cancer cell lines, finding that FA-dependent fluorescence correlates with expression levels of enzymes involved in 1C metabolism. By showcasing the ability of MitoRFAP-2 to identify new information on mitochondrial FA homeostasis, this work provides a starting point for the design of a broader range of chemical probes for detecting physiologically important aldehydes with subcellular resolution and a useful reagent for further studies of 1C biology.
Aprendizaje de arquitectura empresarial mediante prototipo de software de realidad virtual. Caso de estudio
Authors: Camargo Lemos Ricardo David , Castañeda Restrepo María Daniela , Parra Montaño Omar Santiago
Published: April 2024

La dificultad en el aprendizaje de la arquitectura empresarial es una de las problemáticas más comunes en los estudiantes de Ingeniería de Software en el programa de Ingeniería de Sistemas de la Universidad El Bosque, por la densidad de los conceptos, la poca experiencia de los estudiantes en el ámbito laboral, y las escasas herramientas pedagógicas para su enseñanza, entre otras. Este trabajo de investigación se basa en la metodología de investigación acción. Presenta los resultados del diseño y construcción de un prototipo de software de realidad virtual como herramienta que contribuya con el aprendizaje de Arquitectura Empresarial (basado en el marco de referencia The Open Group Architecture Framework), su aplicación a un grupo de estudiantes de la asignatura, y la posterior medición y evaluación del proceso de aprendizaje resultante. Se concluyó que el prototipo es adecuado para reforzar y evaluar conceptos complejos y de una manera didáctica.
Proyectos de diseño mecánico como herramienta para el desarrollo de competencias transversales en los ingenieros
Authors: García Caicedo Jesús Marcey
Published: April 2024

Los proyectos pueden utilizarse para la adquisición de competencias técnicas y el desarrollo de competencias transversales producto de las vivencias y retos superados durante la ejecución del proyecto. En este artículo se describen las experiencias desarrolladas en un curso de diseño mecánico donde a través de la ejecución de proyectos que van desde el planteamiento de una necesidad o problema hasta la construcción y uso, junto con herramientas adicionales como: preparación de eventos académicos y gamificación, han permitido incrementar la adquisición de competencias técnicas y transversales en los participantes tales como: mejores habilidades para el trabajo en equipo, trabajo bajo presión y mayor capacidad de respuesta ante imprevistos. Aparte del mejoramiento de estas competencias, se ha vislumbrado que el uso de proyectos como herramienta de aprendizaje permite incrementar la motivación de los estudiantes y su compromiso para enfrentar asignaturas con un componente técnico profundo, como es el diseño mecánico.
Análisis de la respuesta de los sistemas lineales mediante diversas técnicas, incluyendo el análisis de Fourier para un filtro pasabajas de primer orden
Authors: Llanos Avila Jesús María
Published: April 2024

En este trabajo se presenta el estudio del comportamiento de un filtro pasabajas pasivo de primer orden mediante diferentes técnicas como son, el análisis de la función de transferencia en forma matemática, análisis experimental en laboratorio, simulación mediante programas de software de circuitos, analizando además la respuesta del filtro a una entrada de ruido blanco, y por último se utiliza  el método del análisis de Fourier para relacionar la señal de entrada y la salida del mismo filtro. Adicionalmente se estudia la serie de Fourier para reconstrucción de una señal periódica partiendo de sus armónicos para verificar el comportamiento de las fases de los armónicos y sus respectivas amplitudes al pasar por el mismo filtro con el fin de generalizar la respuesta del sistema a cualquier señal de entrada periódica a la cual se le conoce su serie de Fourier.
Comparativo de los sistemas aseguramiento de la calidad de la educación superior en Colombia y Ecuador
Authors: Acosta Lina , Stefos Efstathios
Published: April 2024

En este trabajo el objetivo fue hacer una revisión de los sistemas de aseguramiento de la calidad de la educación superior vigentes en Ecuador y Colombia, las principales normativas que han orientado los procesos de calidad, desde las Constituciones Políticas como marcos legislativos, hasta las normas más recientes. Esto permitió comprender el camino de la calidad en países tan cercanos y con tradiciones educativas, culturales, sociales y políticas, comunes. La metodología se fundamenta en la revisión documental de las principales normativas que rigen los procesos en ambos países y por ser un trabajo de corte cualitativo, se recurrió a la herramienta de análisis cualitativo Atlas.ti. El artículo se estructura en tres partes: en la primera, una revisión de la normatividad de los Sistemas de Aseguramiento de la Calidad, una segunda parte que presenta un comparativo de los sistemas de los dos países y finalmente algunas reflexiones.
Barrow Holographic Dark Energy Model in Bianchi Type-III Universe with Quintessence
Authors: Mahanta Chandra Rekha , Das Dibyajyoti
Published: April 2024

In this paper, we study a spatially homogeneous and anisotropic Bianchi type-III universe containing cold dark matter and Barrow holographic dark energy within the framework of General Relativity. We assume the cold dark matter and Barrow holographic dark energy to be non-interacting and obtain exact solutions of the Einstein field equations by considering a hybrid expansion law and assuming that the expansion scalar is proportional to the shear scalar. We examine the physical and kinematical properties of the resulting model using parameters such as the Hubble parameter, the anisotropic parameter, the deceleration parameter, the equation of state parameter, the jerk parameter etc. We also examine whether the energy conditions are violated or validated. We find that the Null, Weak, and Dominant energy conditions are fulfilled, while the Strong Energy Condition is violated, which supports the accelerated expansion of the universe. The Statefinder diagnostics have been conducted based on recent cosmological observations. In addition, wereformulated the correspondence between quintessence scalar field and Barrow holographic dark energy model.