bluuebunny/crossref_metadata_2025 huggingface dataset:
Adaptation of the Russian-language Version of Parental Bonding Instrument (PBI)
Authors:   Lomonosov Moscow State University (Moscow, Russian Federation), Tikhomirova T.N. ,   Psychological Institute of Russian Academy of Education, Gaysina D.A. ,   University of Sussex, Malykh S.B. ,   Lomonosov Moscow State University (Moscow, Russian Federation); Psychological Institute of Russian Academy of Education
Published: December 2021

The results of adaptation of the Russian-language version of the Parental Bonding Instrument (PBI) (Parker, Tupling, Brown, 1979) with "Mother's Attitude" and "Father's Attitude" options are presented in the article. The questionnaire is aimed to assess the perception of parenting attitudes among young people. According to the original (English) version of the questionnaire, aspects of parental attitude perception can be measured as quantitative indicators of the questionnaire scales: 1) "Care" and 2) "Overprotection". The "Care" scale consists of 12 statements such as “Seemed emotionally cold to me”, “Enjoyed talking things over with me”, “Did not talk with me very much”, etc. The "Overprotection" scale includes 13 statements such as "Felt I could not look after myself unless she/he was around", "Let me decide things for myself", "Let me dress in any way I pleased", etc. The study involved 504 high school students enrolled in schools in the Moscow and Leningrad regions, Samara and St. Petersburg, aged from 14.4 to 19.1 years, among them were 174 9th grade students (44.2% male), 169 10th grade students (34.7% male) and 161 11th grade students (51.1% male). The structure of the questionnaire was studied using exploratory factor analysis of the correlation matrix of the responses to 25 items of each version. The method of principal components with Varimax rotation was chosen for the analysis. The confirmatory factor analysis suggested the two-factor structure of the questionnaire was confirmed, with the following scales: “Care” and “Overprotection” for the options "Mother's Attitude" and "Father's Attitude". For reliability assessment, the scales were tested with the Cronbach's alpha coefficient of internal consistency. Satisfactory internal consistency of the scales on both options was revealed. The Cronbach's alphas reach satisfactory values both for Care and Overprotection scales. The effects of gender and age on the questionnaire scores were estimated. According to analysis, there are no sex differences of perception of maternal and paternal attitude in both “Care” and “Overprotection” scales. It was shown that the effect of age was statistically significant for “Overprotection” scale for paternal attitude only, with a small effect size. The effect of interaction of age and sex was statistically significant for “Care” for paternal attitude only, with a small effect size. According to the psychometric indicators presented in this paper, the Russian-language version of PBI can become a reliable tool to measure high school students’ perception of the parental attitude.
Influence of Irrational Beliefs and Sensitivity to a Person on Future Psychology Students’ Propensity to Coercion or Nonviolence
Authors:   Cherepovets State University, Maralov V.G. , Sitarov V.A. ,   Moscow City University
Published: December 2021

The relevance of the problem is due to the importance of identifying factors that determine the propensity of students to coercion or nonviolence, creating psychological and pedagogical conditions for the formation of the socionomic sphere of nonviolent competencies for future specialists at universities. The theoretical basis of the study was the position of nonviolence as a daily practice of interaction, by which we understand the ability of a person to choose from a number of possible alternatives that carry the least charge of coercion. The aim of the work was to study the influence of irrational beliefs and sensitivity to a person (interest, empathy, understanding and assistance) on the students’ tendency to coercion, manipulation, non-violence and non-interference in the processes of interaction with people. The hypothesis was tested that the tendency of students to coercion, manipulation, and noninterference will be due to expressed irrational beliefs and low level of sensitivity to a person and the tendency to non-violence will be explained by the absence of irrational beliefs and a high level of sensitivity to a person. The study involved 125 students of pedagogical and psychological faculties of the Moscow Humanitarian and Cherepovets State universities. The authors used questionnaires to identify the positions of interaction among students and sensitivity to a person, as well as a list of irrational beliefs proposed by A. Beck and A. Freeman. It is established that the tendency to both coercion and manipulation are determined by the beliefs of anti-social type and low sensitivity to the person. The tendency to manipulate the narcissistic beliefs, high interest in people and understanding them, at the same time the tendency to non-violence and non-interference are determined by beliefs of avoidant and dependent types with a low level of understanding people. And a tendency to non-interference is determined by beliefs of dependent type with unexpressed orientation on helping. The tendency to nonviolence is determined by the high sensitivity to a person and the absence of irrational beliefs of antisocial, passive-aggressive and narcissistic types. As a result, the conclusion is made about the need to form purposefully the ability to nonviolent interaction among students, which should include the work on awareness and overcoming irrational beliefs and the development of sensitivity to a person. The obtained results can be used in practical work with students on the formation of their nonviolent competencies.
Apathy and Academic Failure among Students: Results of a Pilot Longitudinal Study
Authors:   HSE University (Moscow, Russian Federation), Zolotareva A.A.
Published: December 2021

The current study was aimed to examine the impact of psychological adjustment / maladjustment on the academic performance of Russian university students. Previous studies have shown that academic performance is closely related to alienation from study, study engagement, academic motivation, perceived stress, academic control, and boredom proneness. Some researchers also have suggested that adolescent apathy may be the risk factor for academic failure among university students. In turn, the American psychologist R. Handelman defined adolescent apathy as a specific state of lack of goal-setting, energy and interest, indifference to changes and experience of difficulties in making decisions in young adults [27]. In September 2019, 103 students (73 females and 30 males) aged 16 to 21 years from several Moscow universities filled out instruments assessing adolescent apathy, alienation from study, study engagement, academic motivation, perceived stress, academic control, and boredom proneness. The study was conducted at seminars in psychological disciplines. All study participants received bonus points in these disciplines. In January 2019, based on the results of the examination session, an average score was calculated for each study participant. This score became a criterion for academic performance of university students. There were no statistically significant age and gender differences in the scores of psychological adjustment / maladjustment. The one-way analysis of variance (ANOVA) revealed that adolescent apathy was the single indicator that affects the academic performance of university students. Thus, the higher scores of adolescent apathy university students showed at the beginning of the academic year, the lower the average scores they received for the first exam session. Based on these data, it was concluded that adolescent apathy is a risk factor for academic failure and can serve as a target for preventive and interventional measures related to academic failure among Russian university students. Currently, in foreign practice, programs and recommendations are being developed and implemented for teachers of higher educational institutions who are faced with the adolescent apathy outcomes. Perhaps this study, which has proved the importance of adolescent apathy in the context of academic failure among university students, will be the first step towards the development and implementation of similar programs and recommendations for Russian educational institutions.
MODELING THE ACCUMULATION OF DAMAGES AND THE FAILURE OF CERAMIC COMPOSITES Al2O3-ZrO2, OBTAINED BY ADDITIVE TECHNOLOGIES, UNDER HIGH-SPEED LOADING
Authors:   Tomsk State University (Tomsk, Russian Federation), Promakhov V.V. , Korobenkov M.V. ,   Tomsk State University (Tomsk, Russian Federation), Schultz N.A. ,   Tomsk State University (Tomsk, Russian Federation), Zhukov A.S. ,   Tomsk State University (Tomsk, Russian Federation), Olisov A.V. ,   Tomsk State University (Tomsk, Russian Federation), Bakhmat V.R. ,   Tomsk State University (Tomsk, Russian Federation), Dronov F.Yu. ,   Tomsk State University (Tomsk, Russian Federation), Myalkovskiy I.S. ,   Tomsk State University (Tomsk, Russian Federation)
Published: December 2021

Functional ceramic composite materials are widely used in industry due to their high strength, hardness, high operating temperature, and chemical inertness. Among the most famous types of functional ceramics are the ceramic composites based on the Al2O3-20% ZrO2 system. In this work, the effect of the loading rate on the crack resistance is studied as well as the effect of the crack resistance of ceramic composites Al2O3-20% t-ZrO2 with a mass content of submicron tZrO2 particles on the high-speed compression of model specimens in shock waves and on the high-speed tension in the region of interaction of unloading waves. It is established that nonlinear effects of the mechanical behavior of ceramic composites ZrO2-Al2O3 with a transformationhardened matrix obtained by additive technologies are manifested at shock loading amplitudes close to or exceeding the Hugoniot elastic limit. Nonlinear effects under intense dynamic impacts on the considered composites are associated with the processes of self-organization of deformation regimes at a mesoscopic level, as well as with the occurrence of martensitic phase transformations in the matrix volumes, which are adjacent to strengthening particles. The modeling approach presented in this work can be used to determine the dynamic characteristics of ceramic composites up to shock loads of 1000 m/s.
EFFECT OF TURBULENT PULSATIONS ON THE FRACTIONAL SEPARATION OF FINE POWDERS OF METAL NITRIDES
Authors:   Tomsk State University, Evseev N.S. ,   Institute for Problems of Chemical and Energetic Technologies of the Siberian Branch of the Russian Academy of Sciences (Biysk, Russian Federation), Zhukov I.A. ,   Tomsk State University (Tomsk, Russian Federation)
Published: December 2021

This paper presents a numerical study of a two-phase swirling turbulent flow in a separation element of a vortex chamber. The paper considers a process of fractional separation in the separation chamber with three particular features in its design. The main feature is the separation mobile element located at the outlet of the separation area. Changes in the position of this element can affect the boundary size and the sharpness of the separation. The second feature of the considered separation chamber is the presence of a rotating element along the vertical axis. This element helps to align the field of the circumferential velocity component. The third feature of this chamber is the presence of a branch pipe for the auxiliary gas flow supply intended to push the particles away from the chamber wall and to blow the separated particles in order to prevent them from agglomeration. In this work, the trajectories of the motion of fine nitride particles are calculated taking into account the turbulent diffusion effect. A possibility to control the boundary size of the particles, when moving the separation element located at the outlet of the vortex chamber, is demonstrated. Numerical study results show that the turbulent pulsations cause significant changes in the separation process and affect the boundary size and the sharpness of the separation.
NUMERICAL STUDY OF A SWIRLING TURBULENT FLOW THROUGH A CHANNEL WITH AN ABRUBT EXPANSION
Authors:   Institute of Mechanics and Seismic Stability of Structures named after M.T. Urazbayev (Tashkent, Republic of Uzbekistan), Malikov Z.M. , Madaliev M.E. ,   Fergana Polytechnic Institute (Fergana, Republic of Uzbekistan)
Published: December 2021

A strongly swirling turbulent flow through an abrupt expansion is studied using the highly resolved DNS, LES, and SAS to shed more light on a stagnation region and spiral vortex destruction, though these methods require high computational expenses. The vortex fracture induced by a sudden expansion resembles the so-called vortex rope that occurs in hydropower draft tubes. It is known that large-scale spiral vortex structures can be captured by regular RANS turbulence models. In this paper, a numerical study of a strongly swirling flow, which abruptly expands, is carried out using the Reynolds stress models SSG / LRR-RSM and EARSM with experimental measurements implemented by Dellenback et al. (1988). Calculations are carried out using the finite volume method. The flow dynamics is studied at the Reynolds number of 3.0 × 104 at almost constant large swirl numbers of 0.6. The time-averaged velocity and pressure fields, as well as the root-mean-square values of the velocity fluctuations are recorded and studied qualitatively. The obtained results are compared with known experimental data. The aim of this work is to test the ability of the models to describe anisotropic turbulence. It is shown that the SSG / LRRRSM model is more appropriate for studying such flows.
A STUDY OF RESIDUAL STRESS FORMATION AFTER ELASTOPLASTIC DEFORMATION OF PIPE WALLS, MADE FROM DISPERSE-HARDENED ALUMINUM ALLOY, AS A RESULT OF EXTERNAL PRESSURE
Authors:   Tomsk State University of Architecture and Building, Matvienko O.V. ,   Tomsk State University, Daneyko O.I. ,   Tomsk State University of Architecture and Building; Tomsk State University, Kovalevskaya T.A. ,   Tomsk State University of Architecture and Building; Tomsk State University
Published: December 2021

The formation of residual stresses after elastic-plastic deformation of pipe walls as a result of external pressure is studied using the approach based on a combination of methods of the physical theory of plasticity and mechanics of a deformable solid. As a result of the research, it is found that at the same value of the applied pressure, the thickness of the area subjected to plastic deformation is less for the alloys reinforced with large particles than for those reinforced with small particles. The values of the circumferential and axial residual stresses exceed the value of the radial residual stresses by more than an order of magnitude. Therefore, in the first approximation, the radial residual stresses can be neglected.
Attributive Collocations in the Gold Standard of Russian Collocability and Their Representation in Dictionaries and Corpora
Authors:   Saint Petersburg State University (Saint Petersburg, Russian Federation), Khokhlova Maria V.
Published: December 2021

The article discusses how collocations are represented in Russian dictionaries and how information about them can be covered in a collocation database that is being developed. Such a resource (gold standard) can be in demand when developing applications for teaching or learning Russian as a foreign language and solving other theoretical and applied issues. The aim of the study was twofold: firstly, to analyze how explanatory and specialized dictionaries of the Russian language represent collocations and hence to what extent their data coincide with each other, and, secondly, to investigate how these dictionary collocations are reflected in text corpora. This allows tracing the relation between manually collected data and modern corpora. For the study, the author used the disambiguated subcorpus and the main corpus of the Russian National Corpus (RNC) with a volume of 6 million and 321 million words, respectively, as well as the large Internet corpus ruTenTen with a volume of more than 14.5 billion words. The author considered attributive phrases built according to the “adjective/participle + noun” model. She analyzed 120 collocations with different dictionary index, i.e. the number of dictionaries in which this phrase is given. The following hypothesis was tested: high collocation frequencies correspond to the fact that the item is recorded in several dictionaries. In the analysis, nonparametric analogues of analysis of variance (Friedman and Kruskal-Wallis tests) were used to assess the statistical significance of differences in quantitative data. The frequencies of collocations in corpora of different volume and in different dictionaries were compared. In total, more than 15 thousand examples were processed, less than 0.5% of them were presented in four of the six reviewed dictionaries (five printed and one electronic). The results show data heterogeneity, items selected for a dictionary do not coincide with their frequency characteristics and thus word combinations turn out to be low-frequency. About 34% of the examples are absent in the RNC corpus with removed ambiguity, and about 12% of analyzed collocations are rare (less than 0.01 ipm) even in the ruTenTen corpus. The presence of collocations in several dictionaries indicates their higher frequencies and hence reproducibility in speech. Explanatory dictionaries and collocation dictionaries show the smallest intersection of data. The results show that the amount of data is a crucial issue, and the very phenomenon of collocability should be studied on large corpora.
Jamstvo perspektive u transdisciplinarnoj organizaciji znanja
Authors:   , Kos Denis
Published: December 2021

Viewpoint warrant in transdisciplinary knowledge organization: This doctoral thesis report on original research employed to organize knowledge and provide documentational support in the field of bioethics. More particularly, this doctoral thesis confronts the problem of perspectival ambiguity in bioethics by considering the notion of perspectives as points of access to diverse outlooks on particular phenomena. Knowledge organization as a discipline of library and information sciences has a long research and professional tradition. In the last 25 years a growing number of authors researching interdisciplinary and transdisciplinary knowledge organization are restating and emphasising the problem of the disciplinary foundations of traditional knowledge organisation systems. These foundations is apparent in the very structures of the most accomplished systems like the Universal Decimal Classification. The critique is focused on the monodimensionality and monoperspectivity of traditional systems, and is characterized by a distinct evocation of the concept of perspectives and advocacy for the development of multi-perspective knowledge organization. According to those authors traditional systems can't respond to the needs of interdisciplinary and transdisciplinary researchers. This doctoral thesis deals with viewpoint warrant in interdisciplinary and transdisciplinary knowledge organization in the context of a specific inter- and transdiscipline of integrative bioethics.
Paranephelius (Asteraceae: Liabeae): A case study in high-elevation hybridization and taxonomic insights
Authors: Dillon Michael O. , Zapata Cruz Mario Enrique , Quipuscoa Silvestre Victor
Published: December 2021

Paranephelius Poepp. (Liabeae: Asteraceae) is a genus, here comprised of three species confined to high-elevation Andean habitats from 3°–25°S latitude from northern Peru to northern Argentina. In a prior investigation, sequence data was analyzed from samples throughout the range of the genus to evaluate the morphological variation used in delineating species. This detailed sampling allowed for molecular studies at a fine geographic scale. Within Paranephelius, genetic divergence is low, and not adequate to fully resolve phylogenetic relationships at the species level. Two genetically and morphologically recognizable genomes were reveled in northern Peru; these correspond to P. ovatus Wedd. and P. uniflorus Poepp., respectively. Several accessions possess sequences representing putative hybrids between these two species. These putative hybrids have caused taxonomic confusion in establishing species boundaries in Paranephelius. The molecular analysis suggested that P. asperifolius (Muschl.) H. Rob. & Brettell, distributed in Bolivia and northwestern Argentina, is related to P. ovatus, while it most closely resembles P. uniflorus. Species that have changed status include, P. ferreyrae H. Rob., here within the parameters of P. uniflorus; and P. jelskii (Hieron.) H. Rob. & Brettell, P. bullatus A. Gray ex Wedd., and P. wurdackii H. Rob. are here within parameters of P. ovatus. This study is not intended to be a monograph, but does includes a key to species, descriptions, illustrations, and citation of specimens examined.
Nomenclatural notes on Amomyrtus, Campomanesia, and Psidium (Myrtaceae)
Authors: Landrum Leslie R.
Published: December 2021

In this paper a neotype is chosen for Myrtus luma, a name first proposed by J.I. Molina in 1782 and the basionym of the currently used name, Amomyrtus luma; the illegitimate name Campomanesia sessiliflora var. lanuginosa is formalized with a new description and type; a new variety is described, Psidium striatulum var. rondoniense; and lectotypes are chosen for Psidium cattleyanum var. coriaceum and Psidium thea.
Vascular flora of the Outer Banks, North Carolina, U.S.A.
Authors: Sorrie Bruce A.
Published: December 2021

A complete catalogue of the vascular flora of the North Carolina Outer Banks is presented. Rarity, habitat, distribution within the Outer Banks, and earliest and latest specimens are given for each taxon. The flora contains 1020 species and infraspecific taxa, plus an additional 80 taxa that lack voucher specimens. Some 770 taxa are considered native; 250 non-native. Fifty-one taxa reach their northern range limit on the Outer Banks; 11 their southern limit. Fifty-five taxa are listed as rare in North Carolina; one of them also listed Threatened by the U.S. Fish and Wildlife Service. Twenty-four natural communities are described and assessed for vulnerabil-ity to sea level rise. Prior botanical research is listed chronologically.
[RETRACTED] Kushly CBD Gummies Reviews - Is Kushly CBD Gummies Safe or Not? v1
Authors: CBD Gummies Kushly
Published: December 2021

[RETRACTED]

Recently referenced are the nuances of Kushly CBD Hemp Gummies. This medication is helpful for an individual dealing with some resting issues, apprehension, and misery and skin aggravation or torture.
GENOTYPE × ENVIRONMENT INTERACTION AND STABILITY ANALYSIS FOR HIGH YIELDING DOUBLED HAPLOID LINES OF LOWLAND RICE
Authors: PURWOKO Bambang Sapta , AKBAR Miftahur Rizqi
Published: December 2021

This study was aimed at obtaining information on the effects of G × E interaction on yield among doubled haploid lines (DH) of lowland rice and to obtain stable and high yielding lines. The experiment was conducted in 9 environments (E), namely Indramayu (2018), Subang (2018), Malang I (2018), Malang II (2019), Blitar (2019), Cianjur (2019), Lombok (2019), Bali (2019), and Madiun (2019). A randomized complete block design with 3 replications was used in each location. The genotypes evaluated were fourteen doubled haploid rice lines and two check varieties namely Ciherang and Inpari 18. The results of the combined analysis of variance indicated significant effects of genotype (G), environment (E), and genotype × environment (G × E) interactions on grain yield. G1, G4, G9, G10, G11, G12, G13, and G14 DH lines had higher genotype mean yield than the average. Among those genotypes, the DH line of G9 was classified as high yielding, stable, and widely adapted in all locations based on Francis and Kannenberg, Finlay-Wilkinson, Eberhart-Russell, Kang, and AMMI analyses.
EXERCISE OF THE RIGHT TO A FAIR TRIAL IN CASES RELATED TO DOMESTIC VIOLENCE
Authors:   National University of Life and Environmental Sciences of Ukraine, Golovko Liudmyla , Ladychenko Viktor ,   National University of Life and Environmental Sciences of Ukraine, Gulaс Olena ,   National University of Life and Environmental Sciences of Ukraine
Published: December 2021

The purpose of the article is to investigate the effectiveness of Ukrainian legislation in the fieldof combating domestic violence, as well as the implementation of the right to a fair trial in casesinvolving domestic violence. The following methods were used in the study: analysis and synthesis,system-functional method, comparative method. Results. The article analyzes the legislation ofUkraine in the field of prevention and counteraction to domestic violence, lists both its advantagesand disadvantages, reveals measures in the field of prevention and counteraction to domesticviolence, responsibility for domestic violence, the main directions of state policy in the field ofprevention and counteraction to domestic violence, types of domestic violence. Legal regulation of judicial protection for victims of domestic violence has been studied. Judicial practice in casesrelated to domestic violence was considered. Problems of exercising the right to a fair trial inUkraine in cases related to domestic violence were revealed. Conclusions. Undoubtedly, theadoption of the Law of Ukraine “On Prevention and Counteraction to Domestic Violence”, theintroduction of criminal liability for domestic violence and amendments to a number of regulationsto address domestic violence is a positive step in combating such a negative phenomenon asdomestic violence. At the same time, a significant number of issues remain unresolved. This isespecially true for the resolution of cases of domestic violence and the exercise of the right to afair trial in cases of domestic violence, as well as for the enforcement of court decisions on theissuance of restrictive orders. The need to develop a form for assessing the risks of recurrenceof domestic violence has been demonstrated, as has been done for police officers during theessessment of the need to issue an emergency injunction. The need to enshrine at the legislativelevel what is the preventive work of police officers with the offender and how it is carried outwas proved, because without proper regulation of this issue, this type of special measure tocombat domestic violence is declarative and not applied in practice. In addition, the problem ofrefusal of public and private executive services to enforce court decisions on the establishmentof restrictive measures is pointed out, which also requires legislative regulation. The need tostrengthen the position of the victim of domestic violence by giving her/him the opportunity toclaim compensation for non-pecuniary damage in criminal proceedings was noted.
LEGAL STATUS OF THE COURT SESSION SECRETARY IN CIVIL AND ADMINISTRATIVE PROCEEDINGS
Authors:   National Scientific Center Hon. Prof. M. S. Bokarius Forensic Science Institute of the Ministry of Justice of Ukraine, Kutsenko Kateryna
Published: December 2021

The scientific research is focused on the legal status of the court session secretary in civil and administrative proceedings. The purpose of the article is to determine specific features of the legal status of the court session secretary. The objective of the research is to develop recommendations for amending the current legislation to improve the legal status of the court session secretary. The methodological basis of the research constituted general scientific and special legal methods of cognition. The author has used the method of philosophical dialectics among the general scientific methods, which is revealed through the methods of analysis and synthesis, ascent from simple to complex, from abstract to concrete, modeling, abstraction, idealization and formalization. The special legal methods used in the research combine systemic, theoretical and legal, formal and dogmatic, comparative and legal methods of cognition, as well as the method of state and legal modeling. The norms of legislative acts and by-laws regulating the legal status of this official have been analyzed. The author has defined specific features of the legal status of the court session secretary related to the public service, belonging to the court administration, place and significance in civil and administrative proceedings. Specific features of the legal status of the court session secretaries are to apply the rights and responsibilities of civil servants to them; to appoint them to the position based on the results of the competition; the submission of a declaration of their property status for the previous year before the appointment; to apply restrictions of civil servants and anti-corruption restrictions for them. Remuneration, social and legal protection of the court session secretaries are determined in accordance with the legislation on public service; they exercise their powers within the internal labor regulations established for court staff, they comply with the rules of conduct for court employees and ethical requirements for civil servants in relations with court staff and visitors. Among specific features of the legal status we should name the existence of special grounds for bringing to disciplinary liability, the focus of powers on organizational provision of the case hearing by a judge, the impact of the nature of communication (interaction) of the court session secretary with the participants in the trial on the authority of the judicial power in society, the possibility to file the motion to recuse the court session secretary in civil and administrative proceedings. The author as a result of studying the researched problem has formulated own definition of the “legal status of the court session secretary”. It has been offered to amend the current legislation, which determines the legal status of the court session secretary.
SPECIFIC FEATURES OF THE FORMATION OF CITIZENS’ RIGHT TO USE NATURAL OBJECTS OF THE OWNERSHIP RIGHT OF THE PEOPLE OF UKRAINE IN THE XX CENTURY
Authors:   Law Firm KB Partners, Branovytskiy Viktor
Published: December 2021

The purpose of the article is to clarify the peculiarities of the formation of citizens’ right to use natural objects of the ownership right of the people of Ukraine in the XX century. Methods. The research methodology consists of such methods of scientific cognition as: systematic and structural, historical and legal, comparative and legal, formal and legal, interpretation, deduction, induction, analysis, synthesis, etc. Results. The author studies in the section “Period of power changes on the territory of Ukraine” the peculiarities of the legal regulation of the rights to natural objects in the period from 1917 to 1920 and finds out that there was no single practice of regulating natural management relations at that time in Ukraine, since it changed depending on the region, the authorities whose sphere of influence extended to it and the year of issuance of the regulatory act. The author studies in the section “Soviet period” the specifics of the legal regulation of the rights to natural objects during Ukraine’s stay in the USSR and finds out that the only form of the ownership to all natural objects was state, the natural management concept was significantly developed, the mechanism of administrative and legal provision for the realization of citizens’ right to use natural objects of state property, an extensive system of legislation were formed. The author emphasizes in the section “Period of Sovereign Ukraine” how the approach to the regulation of the rights to natural objects was changed after Ukraine’s secession from the USSR, especially the ownership right of the people of Ukraine to natural resources and citizens’ rights to use them. Conclusions. The author indicates in the conclusions: when and which regulatory legal acts enshrined for the first time the people’s ownership to natural objects, citizens’ right to use natural objects of the ownership right of the people and the procedure to use them at the legislative level; main features of legal regulation of the rights to natural objects in the period from 1917 to 1920, the Soviet period and the period of sovereign Ukraine; the circumstances depending on guaranteeing this right. Finally, the author formulates a position according to which it is necessary to distinguish land plots and other objects that may be owned by others and those that constitute the exclusive ownership of the people due to their value and significance. Besides, the author emphasizes the need to get back to the method of normative and legal regulation of the rights to natural objects, which was used in 1990–1991, when the people of Ukraine were endowed with independent powers and had a real status of the owner to natural resources.
Relations between a social subject and a social institution: philosophical foundations and public policy practises
Authors: Davydov Sergey V.
Published: December 2021

The article deals with theoretical and applied issues of the development of relationships between social (political) subjects and social (political) institutions. In the philosophical aspect, the author notes the alternativeness of theoretical approaches to understanding the role of man in society, where the idea of social institution is opposed by the philosophy of the idea of subjective human activity. In this approach the work of E. Ostrom Managing the Common. Evolution of institutions of collective activity is analyzed and the main conclusion is that the relationship between a social (political) subject and an institution develops harmoniously and integrated is rethink. In connection with disagreement with Ostroms position of the author of this work in a practical aspect, an analysis of various situations is carried out, which show three types of interaction: 1) a strong social subject a strong social institution; 2) a weak social institution a strong social subject; 3) there is a developed social institution, but there is no a social subject. The philosophical analysis allows us to conclude that the sphere of relationships between a social subject and any institution is very heterogeneous. This is most vividly illustrated in the political sphere by the example of city public policy.
Changes of Serum miR-202-3p Level and Its Correlation with Prognosis in Patients with Acute Kidney Injury Induced by Sepsis
Authors: Chen Yueyao , Zhou Shiqun , Li Haixiang
Published: December 2021

To investigate the changes of serum miR-202-3p level and its correlation with prognosis in patients with acute kidney injury (AKI) induced by sepsis. From April 2017 to January 2019, 66 patients with AKI induced by sepsis in our hospital and 70 healthy people in the same period were
selected as the research objects. The levels of miR-202-3p, BUN and Cr in serum were tested. Subsequently, cell experiments were carried out to verify the effects of the decrease of miR-202-3p level on BUN, Cr and cell growth and apoptosis. The risk factors were analysed. Compared with healthy
volunteers, patients with AKI induced by sepsis had higher levels of miR-202-3p, BUN and Cr in serum. When miR-202-3p level was knocked down, the levels of BUN and Cr were declined, cell growth was improved and apoptosis rate was decreased. The risk factors were analysed, and the results revealed
that miR-202-3p, BUN and Cr were independent risk factors for poor prognosis in patients with AKI induced by sepsis. The level of miR-202-3p is elevated in patients with AKI induced by sepsis, which may be a potential biomarker for diagnosis and prognosis of patients with AKI induced by sepsis.
The Impact of Community Health Coalitions On Preventative Health Outcomes: A Systematic Review
Authors: Shockley Emily , Amin Aliya , Savaiano Dennis
Published: December 2021

Background/Objective: Six out of ten deaths in the United States are caused by chronic diseases. There are multiple approaches to prevention and/or early detection of chronic diseases through screenings, nutrition, physical activity, and more. Unfortunately, a large portion of the US population have low rates of preventative care. Community health coalitions have the potential to improve preventative health outcomes by partnering with key members of communities to design programs that best fit community needs. In this systematic review, we examine evidence that community health coalitions can improve preventative health outcomes.
Methods: PubMed, WebofScience, CINAHL, and PsycINFO were searched for (outcome OR health outcome) AND (prevention) AND (diabetes OR hypertension OR cancer OR prenatal) AND (community-based participatory research OR community coalition OR coalition OR health coalition). After screening 490 articles, 30 full-text, peer-reviewed, English articles meeting inclusion criteria of health coalition, prevention, health outcomes reported, and conducted in the United States were reviewed.
Results: 27 of the 30 studies showed community health coalitions having a positive impact. Roughly half of the articles were randomized control trials. Community members and academia were represented in 80% and 77%, respectively, of the coalitions described, while other representations included faith-based organizations, health care, public health, industry, and education. Diabetes and cancer represented 74% of the targeted preventions addressed. 90% of the interventions focused on educating the community, and 33% focused on increasing health screening rates. 60% utilized trained community members to deliver interventions. 60% reported health measurements, 33% reported screening rates, and 30% reported knowledge and awareness.
Conclusion, Impact, & Implications: While the evidence suggests community health coalitions are effective in improving preventative health outcomes, the quality of the studies remain low. There is a need for increased rigor of study design and assessment in order to determine the true efficacy of community health coalitions. The majority of the randomized-control trials in this review were rated as low-quality, highlighting the difficulty of designing a randomized, controlled study in a community. Inadequate funding, lack of rigorous design, or ethical challenges can limit the quality of the assessment. Further, although prenatal care was included as a search term, there were no coalitions found that addressed this type of preventative care. This points to a future need for the creation of or increased publications from prenatal health coalitions.
The Effects of Integrative Palliative Oncology on Hospital Time, Hospice Referrals, and Advanced Care Planning
Authors: Sims Rebecca , McCollom Joseph
Published: December 2021

Background:
Integrative palliative oncology incorporates mental, physical, and familial aspects of care into standard cancer treatment. Patients in these programs have access to a doctor, nurse, psychologist, social worker, and chaplain who are all trained in palliative oncology whereas standard oncology does not have this team. Integrative programs improve well-being while reducing futile treatments. We hypothesize that emergency department (ED) visits, inpatient admissions, intensive care unit (ICU) stays, hospital deaths, hospice referrals, and advanced care planning (ACP) are affected by these programs.
 
Methods:
A retrospective chart review analyzed patients from Parkview Regional Medical Center. Cohort A included 100 patients from a palliative oncology program. Cohort B included 100 patients who received standard oncology care. Cohorts were matched on gender, age, cancer type, and stage. Number of ED visits, ICU admissions, and inpatient stays were analyzed. Hospice referrals, hospital deaths, and ACP documents were also compared.
 
Results:
A T-test showed no difference between ED visits, ICU stays, or inpatient admissions between cohorts. A chi-square analysis also showed no difference in hospice referrals or hospital deaths. However, there were significantly more ACP documents on file for cohort A (p = 0.000132). This suggests that palliative oncology programs do not strongly affect hospital time or hospice referrals but may impact advanced care planning.
 
Conclusion:
Since the benefits of palliative oncology programs do not seem related to hospital time or hospice care, another factor must be responsible for improving patients’ quality of life. These programs emphasize family involvement and planning thus explaining the significant increase in ACP documents. Perhaps this extra support and preparedness also improves patients’ moods and well-being.
 
Impact:
Future studies should involve a larger sample size and focus on psychological aspects of these programs to determine why they benefit patient health, specifically mental health, and what improvements can be made.
Study of Protein Targeting and Mislocalization in Rod Photoreceptors
Authors: Nunez Asael , Takita Shimpei , Imanishi Sanae , Imanishi Yoshikazu
Published: December 2021

The photoreceptor outer segment (OS) is a highly specialized organelle for light absorption. Precise localization of OS resident proteins is important for photoreceptor function. Molecular mechanisms underlying OS targeting of proteins and their mislocalization, which frequently causes inherited retinal degeneration, have been intensely investigated. Rhodopsin, a major protein of the rod OS, is often mislocalized to the inner segment (IS) plasma membrane of rod photoreceptors in retinal degeneration patients. In the Xenopus laevis model of retinitis pigmentosa, we previously found that Na+/K+-ATPase (NKA), a major IS protein, was downregulated. The Imanishi lab recently created a novel retinitis pigmentosa mouse model carrying the Q344ter rhodopsin gene mutation, which causes rhodopsin mislocalization to the rod IS plasma membrane. In this summer program, we examined whether this mouse model also displays reduced NKA expression in the rod IS’s by immunohistochemistry at postnatal day 30. Although NKA was properly localized to the IS plasma membrane, expression of NKA was reduced in mutant photoreceptors compared to wildtype cells. In the rod OS, activation of rhodopsin eventually leads to the closure of the cyclic nucleotide gated (CNG) channel, which consists of a and b subunits. This channel localizes to the OS plasma membrane, and the N-terminal proline-rich region (R) of the b subunit (CNGb1) may be important for its interaction with peripherin (PRPH2), another OS resident protein. Currently, it is not well understood whether this interaction is necessary for the proper localization of CNGb1 to the OS plasma membrane. Using Xenopus as a model, we studied the role of the N-terminal proline-rich region in properly localizing CNGb1 to the OS plasma membrane by generating transgenic CNGb1(DR) tadpoles that expressed CNGb1(DR) in rods under the control of a rhodopsin promoter. We found that CNGb1(DR) properly localized to the OS plasma membrane.
Brain Resting State Functional Networks in Infants with Prenatal Opioid Exposure
Authors: Steinhardt Nicole , Vishnubhotla Ramana , Zhao Yi , Haas David M. , Sokol Gregory M. , Sadhasivam Senthilkumar , Radhakrishnan Rupa
Published: December 2021

Purpose:
Infants of mothers with opioid and substance use can present with postnatal withdrawal symptoms and are at risk of poor neurodevelopmental outcomes in later childhood. Identifying methods to evaluate the consequences of substance exposure on the developing brain can help initiate proactive therapies to improve outcomes for opioid-exposed neonates. Additionally, early brain imaging in infancy has the potential to identify early brain developmental alterations that could prognosticate neurodevelopmental outcomes in these children. In this study, we aim to identify differences in global brain network connectivity in infants with prenatal opioid exposure compared to healthy control infants, using resting-state functional MRI performed at less than 2 months completed gestational age.
 
Materials and Methods:
In this prospective, IRB-approved study, we recruited 20 infants with prenatal opioid exposure and 20 healthy, opioid naïve infants. Anatomic imaging and resting-state functional MRI were performed at less than 48 weeks corrected gestational age, and rs-fMRI images were co-registered to the UNC neonate brain template and 90 anatomic atlas-labelled regions. Covariate Assisted Principal (CAP) regression was performed to identify brain network functional connectivity that was significantly different among infants with prenatal opioid exposure compared to healthy neonates.
 
Results:
Of the 5 significantly different CAP components identified, the most distinct component (CAP5, p= 3.86 x 10-6) spanned several brain regions, including the right inferior temporal gyrus, bilateral Hesch’s gyrus, left thalamus, left supramarginal gyrus, left inferior parietal lobule, left superior parietal gyrus, right anterior cingulate gyrus, right gyrus rectus, left supplementary motor area, and left pars triangularis. Functional connectivity in this network was lower in the infants with prenatal opioid exposure compared to non-opioid exposed infants.
 
Conclusion:
This study demonstrates global network alterations in infants with prenatal opioid exposure compared to non-opioid exposed infants. Future studies should be aimed at identifying clinical significance of this altered connectivity.
Nonmetastatic Colon Cancer Model C26 Upregulates Glycolysis in Osteocytes in Vitro and Bone in Vivo
Authors: Tollar M. Roarke , Prideaux Matthew , Pin Fabrizio , Bonewald Lynda F.
Published: December 2021

Background: Developing effective treatments for musculoskeletal complications in cancer patients requires understanding metabolic effects of cancer on bone, and particularly osteocytes, the most abundant bone cell and key regulator of bone remodeling. However, little is known regarding how cancer impacts normal osteocyte energy metabolic pathways, such as glycolysis. Given that changes in metabolism are important regulators of cellular function, it is essential to determine how osteocyte metabolism is disrupted by cancer and how this may impact skeletal and whole-body health.
Methods: Mice inoculated with saline (N=5) or C26 cells (N=6) were sacrificed after 2 weeks. Bones were harvested for metabolic profiling by GC-MS, gene expression by RT-PCR and bone morphology by µCT. Differentiated IDG-SW3 osteocyte-like cells were cocultured with C26 cells for 12-24hrs and metabolites and gene expression analyzed by GC-MS and RT-PCR.
Results: Trabecular bone mass was significantly decreased in the C26 mice. GC-MS analysis revealed decreased glucose in C26 mice tibiae, but no change in lactate. The bone resorption promoting gene Rankl was upregulated, whereas the inhibitor Opg was unchanged. Bone mineralization regulators Mepe and Phex were decreased. In vitro metabolic studies revealed increased glucose and lactate in IDG-SW3 cell lysate; culture media glucose levels were decreased whereas lactate was increased in the co-cultures with C26 cells. RT-PCR demonstrated increases in the glycolysis promoter Hif1α in addition to glycolysis pathway genes including Glut1, Hk2, Slc16a3 and Pdk1. Rankl was also increased in the IDG-SW3 cells co-cultured with the C26 cells whereas Opg, Phex, and Mepe were downregulated.
Conclusion: Glycolysis is upregulated in mouse bone and in vitro IDG-SW3 cells exposed to cancer. Our study provides novel understanding for how cancer affects bone metabolism. Integrating these results with whole body metabolism will aid in the development of novel therapeutic strategies to target musculoskeletal and systemic complications of cancer.