bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of Hydrogen Bonding and Hydrophobic Interactions on the Stabilization of
Myoglobin (Globular Protein)-Primaquine-4-Dicyanomethylene-2,6-Dimethyl-4H-pyran
(DDP) Conformers
Authors: Sangeetha Murugan Sreedevi , Vinod Seba Merin , Kumaran Rajendran
Published: November 2022

Molecular docking (MD) approach on the binding interaction of two competing ligands with a
well-known globular protein, myoglobin (MB) was carried out. Docking studies of 4-dicyanomethylene-
2,6-dimethyl-4H-pyran (DDP) dye and an anti-malarial drug, primaquine (PRQ) were considered as
the guest molecules in the presence of myoglobin as the host molecule. Docking studies of
dye-myoglobin conformers reveals that the dye resides predominantly in between the helices C and D,
which are stabilized and governed by hydrogen-bonding interactions. Further, the dye is also stabilized
through hydrophobic interactions when confined to E and F helices of the protein. However, the drug
prefers to reside in all the domains of the polypeptide chain structure of myoglobin resulting in a
larger stability when compared to that of dye-protein complex. Interestingly, the displacement of dye
from the binding sites of myoglobin was found to be ineffective in the presence of drug. On the
contrary, the dye efficiently displaces the drug entirely to a single confined region (between C and D,
E and between F and G) of the protein molecule. Docking studies signifies that the hydrogen bonding
donor and acceptor sites were involved in the stabilization of complex thereby provides a clear
elucidation on the binding nature of two competing guest molecules in the presence of host molecule.
Molecular docking technique was used as an efficient and reliable tool to determine the various
bimolecular interactions existing between protein-dye and protein- drug complexes.
Platinum Group Metals Bonded Thiolato Sulfur Oxygenation: Photoactivity and Bioactivity
Authors: Das Ujjwal
Published: November 2022

Platinum group metals mediated thiolato compounds are highly susceptible for S-centered reactivity
owing to high nucleophilicity and which is enormously significant in the point of its bioactivity and
photoactivity. A series of oxygenation reactions of thiolate sulfur attached with platinum metals occurred
with molecular O2 in varying conditions. A variety of sulfenates and sulfinates are produced depending
on nature of starting substrate thiolato and the oxygenations are facile under harshly oxygen
environment. There are numerous mechanistic paths for the oxygenation of platinum metals bonded
thiolate S-center unlike the oxygenation reaction of organic sulphides. It is assumed that S-oxygenation
occurs via the intramolecular and intermolecular dioxygen addition pathways. A number of mysterious
photo-induced sulphur oxygenation and self-sensitization reactions of metal-thiolato to analogous
oxygenate are also mentioned. These compounds show enzymatic catalytic activity and remarkable
bioactivity also interaction with the biomolecules like DNA, which opens a new area for the researchers
for designing novel heavier metals-sulfur-oxygenates compounds as metallodrugs.
Fabrication, Characterization and NH3 Sensing Properties of Zinc
Supported TiO2 Doped Polypyrrole Nanocomposite Thin Films
Authors: Patil Anand , Patil Nirdosh
Published: November 2022

A series of conductive and porous Zn/TiO2 doped polypyrrole (PPy) nanocomposites thin films were
prepared by adding Zn/TiO2 (5, 10, 15, 20 and 25 wt.%) in an aqueous solution of polypyrrole using
a chemical oxidative polymerization process at room temperature. The prepared Zn/TiO2-PPy films
were characterized by electrical resistivity by two probe techniques, Fourier transform infrared (FTIR)
spectroscopy, X-ray diffraction (XRD) and scanning electron microscopy (SEM). The surface
morphology of Zn/TiO2-PPy films has found signicant influence on the gas sensing properties. Results
from FTIR and XRD verified the structural formation of Zn/TiO2-PPy films from the pyrrole monomer.
When the amount of Zn/TiO2 increased, the optical absorption in visible (500-700 nm) and UV (200-400
nm) regions decreases, according to an analysis of the optical characteristics of all tested films. The
NH3 gas was used to examine the prepeared nanocomposites thin films’ sensing properties.
Assessment of Impact of Human Interferences including Mining
Activities on Water Quality of Banas River, Rajsamand City, India
Authors: Pal Deepak , Tripathi Ashutosh , Hussain Tahir , Jindal Tanu , Shukla Kartikeya
Published: November 2022

An attempt has been made in the present study to assess various physico-chemical parameters and
heavy metal analysis of water quality in Banas river, Rajsamand city, India. To maintain a balance in
an aquatic ecosystem, the inter-relationship between varieties of factors is essential to maintain the
water potability at a high level. It is confirmed that mining has a substantial influence. Present study
examined pre- and post-monsoon physico-chemical variables, heavy metal analysis and computed
water quality index, eutrophication index, organic pollution index and heavy metal pollution index.
The pH, EC, COD, total hardness, zinc, silver and iron were within the acceptable limit, whereas the
TDS, phosphate, dissolved oxygen, BOD and lead were found beyond the permissible limit. Therefore,
the present study provides the essential information about deteriorating river water quality. Most
crucially, a number of external factors like mining, soil erosion, religious activities, daily human
needs activities, etc. are responsible for the degradation of water quality of nearby Banas river.
An Efficient and Ecofriendly Synthesis of
3,7-Diaryltetrahydro-1H,5H-[1,2,4]triazolo[1,2-a][1,2,4]triazole-1,5-dithiones
Authors: Mallikarjunaswamy A.M.M. , Vijaya Bhuvaneshwari S. , Khatik Gopal L. , Chopra Sidharth , Akhir Abdul , Saxena Deepanshi , Nair Vipin A.
Published: November 2022

An efficient and environmentally friendly method was developed for the synthesis of 3,7-diaryltetrahydro-
1H,5H-[1,2,4]triazolo[1,2-a]-[1,2,4]triazole-1,5-dithiones by reacting aldazines with KSCN and HCl
in an ethanolic medium. The products were obtained in excellent yields within short duration of time,
along with the advantage of ease of isolation by precipitation. The reaction mechanism substantiates the
formation of a protonated intermediate, which facilitates an accelerated nucleophilic addition. Among
the compounds synthesized, the 3,7-bis(4-chlorophenyl)tetrahydro-1H,5H-[1,2,4]triazolo[1,2-
a][1,2,4]triazole-1,5-dithione demonstrated remarkable antibacterial properties.
Synthesis, Characterization and Applications of Plain and Non-Metal Doped,
Biomass-Derived Carbon Quantum Dots: A Short Review
Authors: Padmapriya A. , Krishnaveni R. , Kalaivani R.A. , Shanmugharaj A.M.
Published: November 2022

Carbon dots (CDs) are very small particles have acquired research interest in the last few years, due to
their unique characteristics like low-cost synthetic protocols, fast and flexible modification procedures
and low toxicity. These CDs exhibit excellent physical and chemical properties like high crystallization,
superconductivity, electronic conductivity, etc. and hence they establish themselves as massive entrants
in emerging fields of applications like chemical sensors, nanomedicines and electrocatalytic reactions.
Functional nanosensors with luminescent properties are in high demand in bioanalysis and doped
carbon dots play a great role in this feature. The elements viz. B, C, N, P and S doped carbon dots are
used in the detection of metal ions in biological samples, bioimaging and DNA studies. This critical
review examines the environmentally friendly techniques of synthesizing doped/undoped carbon
quantum dots from biomasses, with an emphasis on their electrochemical and luminescent applications.
Effect of Photodegradation on Ternary FeNiS2 Thin Film with
Complexing Agents EDTA and Leishman Stain
Authors: Gayathri G.D. , Thiruneelakandan R.
Published: November 2022

The aim of this study is to analyze the photocatalytic dye degradation efficiency of FeNiS2 with EDTA
and Leishman stain thin films prepared using a sol-gel technique. The results of surface morphology
and elemental composition, optical characterization of these films obtained using various
characterization techniques such as SEM, EDX, UV-VIS spectroscopy. The photocatalytic studies
show that the addition of EDTA and Leishman extraordinarily enhances the photocatalytic efficiency
of FeNiS2. The FeNiS2 with EDTA, FeNiS2 with Leishman stain thin films causes 92%, 90% and 89%
decomposition of methylene blue, malachite green and crystal violet dye molecules, respectively.
An Efficient, Novel Synthetic Route to (R)-Salmeterol Xinafoate and Facile
Synthetic Protocols for Preparation of its Process Related Potential Impurities
Authors: Boodida Sathyanarayana , Gudla Parandhama , Maddula Srinivasula Reddy
Published: November 2022

In present work, an effective, innovative enantioselective synthetic strategy for the synthesis of
salmeterol xinafoate and its probable process-related impurities was reported. Seven pharmacopeia
specified impurities were synthesized and confirmed by FT-IR, mass, 1H & 13C NMR spectroscopy.
With respect to the corresponding retention factors, these contaminants were validated using the
available RP-HPLC method. These compounds can be used as a reference standard for the active
pharmaceutical ingredient manufactures and research organizations.
On the Question of the Views of A.S. Pushkin on the Insurrection in Poland in 1830-1831
Authors: Shirokova M.A.
Published: November 2022

The article deals with the political ideas expressed by A.S. Pushkin, first of all, in the poem "To the Slanderers of Russia", as well as in personal correspondence and notes from the period of the Polish insurrection of 1830-1831. An overview of the prehistory and prerequisites for the insurrection is given, the historical context is shown, which determined the formation of the poet's views on the "Polish question". Pushkin's worldview was influenced by the "History of the Russian State" by N.M. Karamzin and, in particular, the story about the occupation of Moscow by Polish troops in 1610-1612. In addition, the poet, like his contemporaries, retained direct impressions of the Patriotic War of 1812, in which the Poles participated on the side of Napoleon. The ode to "Slanderers of Russia" was Pushkin's answer to members of the French Parliament, who raised the issue of supporting the Poles. For the French liberals, the events in Poland were of international significance and were characterized as the struggle of one of the emerging European nations for rights and freedoms. For Pushkin, the Polish rebellion was exclusively an internal affair of Russia, an encroachment on its integrity. The article presents the statements of some representatives of Russian culture who were part of Pushkin's circle of friends, among whom were both supporters and opponents of the state-patriotic position of the poet.
The Anthroponym of Prince Oleg Veshchy (The Seer) as a Possible Legacy of the Venetians
Authors: Пивень Павел Владиславович
Published: November 2022

The article is devoted to the problem of the origin of the name of Oleg Veshchy (The Seer). On the basis of the data of the historiography of Ancient Rus', historical geography, genogeography and linguistics the possible variants of belonging of the given anthroponym to a concrete ethnos and region are analyzed. Using archaeological data and toponymic markers it was shown that the names of the princes of Varangian Rus can be nicknames-demonyms, locating on the territories adjacent to the lower course of the river Odra, belonging to the tribal alliance of the Slavs-Pomorians. It was shown that the demonim "Oleg" may be derived from the Slavic town of Ologost (Ologoshch) Land, located near the Slavic town of Ologost (Volgoshch), modern Volgast. Also the facts of the existence of the Rokhovskaya Land (Rukhovskaya), located on the southern shore of the Szczecin gulf, which may be associated with the remnants of the Rugi tribe assimilated by the Slavs, including those indicated as "Ruses", were cited. Evidence is given that the toponym Voloshch and, respectively, the anthroponym Oleg may be derived from the name of the chthonic god-patron of Veles (Volos), and the basis of this cult may be pre-Slavonic, possibly Venetian and toponymic markers which can be traced to the northern part of the Asia Minor.
Markers of Ethnic Identity of the Russian-Ukrainian Population in Russia (Based on Field Research in European Russia, Siberia, and the Far East, 2020-2021)
Authors: Lyulya N.V.
Published: November 2022

Based on field materials obtained during ethnic sociological expeditions in 2020-2021 to the regions of the Russian Federation (Belgorod, Voronezh, Omsk regions, Primorsky, Altai Territory), the author defines and characterizes markers of the ethnic identity of Russian-Ukrainian biethnors (commonality of historical fate, commonality of territory, religion, life, family order, norms of behavior, commonality of psychological warehouse, language). According to the results of the study, it was revealed that the commonality of the historical past is the preservation and broadcast of family stories; the commonality of the territory in the broad sense can be considered the territory of the Russian Federation; Orthodoxy acts as a marker of religiosity, as an integral part of the culture of Russian-Ukrainian biethnors; life, family order is determined from the position of perception of identity by respondents, and food as the brightest element; norms of behavior, mentality are defined by different character traits (thrifty, strong, etc.); the language of the group in question is Russian, with the preservation of Ukrainian and Khokhlyak ones in everyday life. Each of the identified markers defines both Russianism and Ukrainism as a component of the double ethnic identity of the group.
NOTAS PARA O TRABALHO COM A HERMENÊUTICA NA PESQUISA EM EDUCAÇÃO
Authors: Matos-de-Souza Rodrigo
Published: November 2022

O presente ensaio busca nas teorias schleiermacherianas e ricoeuriana uma proposição para o trabalho de interpretação textual nas pesquisas educacionais. Entendendo que a Hermenêutica pode oferecer, em si, um caminho teórico, metodológico e de análise para os exercícios de linguagem que prefiguram muitos trabalhos do referido campo de investigação, em especial, os trabalhos de análise de textos e documentos, de entrevistas, de grupos de discussão e focal, e no trabalho com o outro que essas técnicas e instrumentos de coleta fornecem. A partir das abordagens teóricas da Hermenêutica Textual e da Teoria da Interpretação, as notas aqui apresentadas investigam o processo de construção de um projeto hermenêutico, em suas particularidades. Além disso, aproxima-se da pesquisa em educação provocando-a a se reconectar com a crítica, um papel que sempre desempenhou, mas, que, nas últimas décadas vem sendo substituído pela escrita, sempre aligeirada, pragmática, que deixa pouco espaço para a leitura e interpretação do que se lê. Conclui conclamando os pesquisadores do campo ao uso das teorias de interpretação, ao trabalho cuidadoso com a linguagem do outro e às muitas aberturas que esse exercício de alteridade nos apresenta.
ALÉM DA SALA DE AULA
Authors: Lima de Arruda Robson , Nádia Araújo Nascimento Robéria
Published: November 2022

Enquanto lócus de vivências e sociabilidade, a escola é um espaço legítimo de produção de saberes e conhecimentos. No entanto, durante a pandemia da Covid-19, essas experiências foram interrompidas, demandando novos arranjos em outros espaços e de outras formas. Nessa direção, o presente estudo ouviu 48 entrevistados de seis cidades do Estado de Pernambuco e Paraíba sobre como se deu o processo de ruptura do ensino presencial para o ensino remoto. Trata-se de um estudo de natureza descritiva que mescla dados quantitativos e qualitativos, cujos resultados enfatizaram aspectos da (in)viabilidade do ensino remoto, considerando critérios da inclusão tecnológica, qualidade e eficiência dos processos e, além disso, destacou o papel da família nas novas mediações e interações de aprendizagem.
ESTADO DA ARTE DOS MEMES
Authors: Carlos Terrado Luisyane de Maria , Barros Rocha Aranha Marize
Published: November 2022

Este artigo tem como objetivo fazer um inventário das produções científicas relativas ao trabalho com memes de internet nas aulas de Língua Portuguesa. Para tanto, segue uma abordagem qualitativa utilizando-se uma metodologia de revisão de literatura do tipo estado da arte, a fim de sistematizar o que tem sido pesquisado e disseminado sobre o tema em 15 publicações em revistas e 11 dissertações. Dentre as produções, artigos científicos publicados em revistas nacionais e dissertações localizadas no Google Acadêmico, periódicos da CAPES, portais de congressos, Bibliotecas Digitais, e outras, na última década no Brasil. Todo o compilado foi analisado através da leitura do título, resumo e das palavras-chave, bem como qual tem sido a contribuição dos memes para o processo de ensino e aprendizagem dos alunos. Como principais resultados apontamos algumas reflexões e a indicação de algumas lacunas que acreditamos serem passíveis de investigações mais aprofundadas futuramente.
ROTAS ANALÍTICAS EM CÓDIGO DE ONTOLOGIA CRÍTICA
Authors: Jaramillo Oscar
Published: November 2022

Neste texto são concebidas rotas analíticas desde os códigos foucaultianos sobre a ontologia crítica de nós mesmos, a qual tem como intuito inquirir sobre a forma na qual estamos sendo produzidos e nos significamos no meio deste presente que hoje nos permeia. Assim, estendem-se categorias de análise que podem ser usadas na pesquisa ontológica como eventualização e problematização, para continuar com a reflexão sobre as práticas de si antigas e a possibilidade de uma virada às práticas de si contemporâneas como rota adequada para analisar a produção de subjetividades na atualidade. Logo disso, propõe-se uma matriz analítica que volta e amplia a categoria de prática de si, proposta por Foucault trabalhando sobre as quatro dimensões que a constituem: substância ética, ligação à prática, tipo de prática e teologia do sujeito moral, além da dimensão que acrescenta Sáenz, agente da substancia ética. Estas, expandem-se desde os eixos genealógico, estético, relacional, pragmático e de mathesis ontológica.  Em suma, estas categorias e dimensões são apresentadas em meio de uma reflexão que permite uma análise para problematizar as formas de governo da vida nos tempos que transcorrem, para ali, inteligir as relações de poder que operam no capitalismo neoliberal globalizado, como governo de uns homens sobre outros para acrescentar o controle sobre os sujeitos ou una prática de liberdade ético-política que atinge resistir ao poder desde o governo de si próprio.
Introduction
Authors: Šmejdová Barbora
Published: November 2022

Editorial
The Stranger in the Bible: The Needy and the Brother
Authors: Dosoudil Jiří
Published: November 2022

The article explores the Bible’s relationship to immigrants and people perceived by society as foreigners. The topic is addressed against the backdrop of ongoing society-wide discussions about helping people who have been forced to leave their homes as a result of the February 2022 Russian aggression in Ukraine: outlining how the Bible addresses the issue of acceptance and coexistence with refugees and immigrants is intended primarily as a contribution to the debate in a Christian forum. It shows that the Old Testament society, as long as they were willing to accept the required way of life, treated these people kindly and forbade any disadvantage to them by the local society. The Israelites, it is recalled, were themselves guests in Egypt, so foreigners in Israel should remind them of their own identity as suffering but also God-delivered people. In the New Testament, this attitude is elaborated in a new theologically anchored universalism: the stranger is spoken of in a figurative sense, but in practice, the barriers between the local and the stranger are overcome. The stranger, here as an unknown person, a traveller, is one of the persons in need, and by helping him, the Christian fulfils the gospel of Jesus and meets with God. Although some circles in the Early Church tended to oppose the values and customs of the outside world, they never resigned themselves to the ideal of practically lived brotherly love, which newly included the stranger and the unknown. The paper proves that love for foreigners, regardless of their origin or circumstances, is organically rooted in the Bible and Christian ideals.
Question of Dispensation of the Intrinsically Evil Acts According to St. Thomas Aquinas
Authors: Lovás Peter Samuel
Published: November 2022

If some action is intrinsically evil, it lacks all moral goodness. This act keeps some physical goodness in the sense that it is real, but it suffers from a real deficient moral disorder. It is morally evil in its essence because its moral privation shapes its objective character. Its disorder defines the act at its core. Such an act is not only affected by evil; it is constituted by evil. The evil shapes the formality and the identity of the action itself. St. Thomas Aquinas argues that these actions cannot be rightly performed under any circumstances and for no end. However, could Almighty God in some specific situations give a dispensation from the negative absolute prohibition? Some biblical cases seem to support this explanation. In many morally difficult situations, some kind of mental reservation, or dispensation that would render an otherwise evil act at least morally permissible, might be very convenient. Aquinas explains that God cannot dispense from the precepts of the decalogue because he would deny himself, who is Justice itself. We will see how it was possible to order Abraham to kill his son and other similar morally disputed cases. Later, we will consider cases of lying and fraud, which frequently appear in the Bible.
The Syncretism of the Gabonese Bwiti Religion and Catholic Christianity from a Theological and Theological-Ethical Perspective
Authors: Havelka Ondřej
Published: November 2022

The article deals with the theology and theological ethics of syncretism of the traditional Gabonese Bwiti religion and Catholic Christianity in equatorial Africa. Traditional Bwiti religious rituals are based on the consumption of the root of the iboga shrub, which has strong psychedelic effects. In Gabon, some believers profess syncretism, which is enshrined in the Bwiti initiation ritual through the Catholic Sacrament of Penance, the Holy Communion, Christian prayers, etc. These Catholic Christians thus undergo a complex and physically demanding initiation process in Gabon. The aim of the paper is to answer the basic question of the whole text, i.e. is the psychedelic initiation ritual in the depths of the Gabonese rainforest consistent with the theological and theological-ethical foundations of the Catholic Christian life? The topic is elaborated by the method of own field research, supported by a comparison of relevant literature. Between 2001 and 2019, the author spent a total of three years on research stays in Africa, of which 12 months were devoted to West and Central Africa and the study of local syncretisms.
From Liberal to Social Vision of Human Rights: The Innovative Contribution of Socialism to Social and Economic Rights
Authors: Vilanculo Anselmo
Published: November 2022

Liberalism and Socialism as well as the contribution of Socialism to Social and Economic Rights (SER) is explored. Enjoyment of Human Rights in different milieus is a result of differences between Liberal and Social understanding and approaches of Human Rights. Liberal approaches founds their roots in the Enlightenment movement and values of nation-state, rights to life, freedom of expression, civil liberty and property. Socialism has its foundations in the Marxist theories. Social relativism and relativism of rights challenges the Liberal universalism of rights. In Socialism, Social and Economic Rights are emphasized. Both Liberalism and Socialism have strengths and weaknesses. As so, the future of Human Rights depends on the combination of approaches, complementarities and synergies, which will result in a multiplicity and plurality of approaches toward Human Rights protection and promotion.
O bezpośredniości interesu prawnego w prawie administracyjnym
Authors: Jakimowicz Wojciech Jakimowicz
Published: November 2022

The aim of the article is to draw attention to the direct nature of the legal interest and to try to answer the question about the sources (grounds) of this interest. The analysis is carried out from the perspective of understanding individual interest in administrative law and focuses on the issues of qualifying legal interest, including law from the perspective of the nature of the relationship between individual interest and its normative basis, and from the perspective of the normative foundations for protecting this interest. It also refers to the issue of the axiological determinants of directness legal interest in administrative law. The analysis here justifies the conclusion that the source of legal interest in administrative law comprises substantive norms belonging to the entire system of generally applicable law, which objectify the individual interest, and only the close relationship between individual interest and the legal norm which is the source of this interest allows such interest to be defined as a legal interest. The lack of a close relationship between the individual interest and the legal norm, which is considered as the source of this interest, allows such an interest to defined, from the perspective of administrative law, only as a factual interest. The close bond that must exist between an individual interest and the legal norm on which it is based in order for such an interest to be classified as a legal interest is expressed by the characteristic defined as the directness of the legal interest. The article also presents arguments to justify the thesis that the mere need to protect a legal interest, or even real protection provided to a legal interest in the area of civil law, does not constitute a source of legal interest in the area of administrative law. Just as the source of the legal interest should be sought in the norms of generally applicable law, the legislator decides on the protection and the degree of protection for this interest by establishing appropriate separate legal norms in this respect.
Maternal use of methamphetamine induces sex‐dependent changes in myocardial gene expression in adult offspring
Authors: Dague Alex , Chavva Hasitha , Brazeau Daniel A. , Denvir James , Rorabaugh Boyd R.
Published: November 2022

Methamphetamine is a commonly abused illicit stimulant that has prevalent use among women of child‐bearing age. While there are extensive studies on the neurological effects of prenatal methamphetamine exposure, relatively little is known about the effect of prenatal methamphetamine on the adult cardiovascular system. Earlier work demonstrated that prenatal methamphetamine exposure sex dependently (females only) sensitizes the adult heart to ischemic injury. These data suggest that prenatal exposure to methamphetamine may induce sex‐dependent changes in cardiac gene expression that persist in adult offspring. The goal of this study was to test the hypothesis that prenatal methamphetamine exposure induces changes in cardiac gene expression that persist in the adult heart. Hearts of prenatally exposed female offspring exhibited a greater number of changes in gene expression compared to male offspring (184 changes compared with 74 in male offspring and 89 changes common between both sexes). Dimethylarginine dimethylaminohydrolase 2 and 3‐hydroxybutyrate dehydrogenase 1 (genes implicated in heart failure) were shown by Western Blot to be under expressed in adult females that were prenatally exposed to methamphetamine, while males were deficient in 3‐Hydroxybutyrate Dehydrogenase 1 only. These data indicate that prenatal methamphetamine exposure induces changes in gene expression that persist into adulthood. This is consistent with previous findings that prenatal methamphetamine sex dependently sensitizes the adult heart to ischemic injury and may increase the risk of developing cardiac disorders during adulthood.
The Ebla Chancery Texts in the Light of Recent Linguistic Research
Authors: Arkhipov Ilya , Kogan Leonid
Published: November 2022

The article aims at establishing new, more reliable meanings and functions for a number of lexical and semi-grammatical elements of Eblaite (Syrian East Semitic). The so-called “chancery texts”, first published by Pelio Fronzaroli and Amalia Catagnoti as ARET 13, 16 and 18, are in the focus of the analysis. While feasible contextual interpretation is an absolute priority for the present authors, other (notably, comparative) methods are also used when applicable. As a result, a substantial progress in our understanding of these exceedingly difficult documents is expected to be achieved.
Penalized logistic regression with prior information for microarray gene expression classification
Authors: Genç Murat
Published: November 2022

Cancer classification and gene selection are important applications in DNA microarray gene expression data analysis. Since DNA microarray data suffers from the high-dimensionality problem, automatic gene selection methods are used to enhance the classification performance of expert classifier systems. In this paper, a new penalized logistic regression method that performs simultaneous gene coefficient estimation and variable selection in DNA microarray data is discussed. The method employs prior information about the gene coefficients to improve the classification accuracy of the underlying model. The coordinate descent algorithm with screening rules is given to obtain the gene coefficient estimates of the proposed method efficiently. The performance of the method is examined on five high-dimensional cancer classification datasets using the area under the curve, the number of selected genes, misclassification rate and F-score measures. The real data analysis results indicate that the proposed method achieves a good cancer classification performance with a small misclassification rate, large area under the curve and F-score by trading off some sparsity level of the underlying model. Hence, the proposed method can be seen as a reliable penalized logistic regression method in the scope of high-dimensional cancer classification.
Reception of Scripture in Rashi’s Torah Commentary
Authors: Eisenstat Yedida
Published: November 2022

The most influential biblical commentary in Jewish history is that of the late eleventh century scholar, Rabbi Shlomo Yitzḥaki (“Rashi”) of northern France. This essay examines Rashi’s Torah Commentary as a midrashic anthology and examines Rashi’s reception of the Bible through the lens of his use of midrash. After highlighting shared traits of first-millennium midrashic corpora and Rashi’s Torah Commentary, I offer a new reading of Rashi’s “methodological statement.” I then turn to Rashi’s historical context to suggest that the Commentary’s lemmatized form demonstrates that Scripture cannot be properly understood without its rabbinic accompaniment, the midrash of the rabbis’ Oral Torah. Finally, I offer examples of the range of ways Rashi employed midrash in his Commentary, the primary lens through which traditional Jews have received Scripture for a millennium.
Effect of carrier (hole) temperature on performance of optical amplifiers quantum dot structure
Authors: Ghazai Alaa Jabbar , Flayyih Ahmed H. , Attab Rasool R. , Al-Khursan Amin H.
Published: November 2022

Carriers temperature in quantum dot (QD) optical amplifiers has been modelled theoretically taken into account hole contribution, which is not considered early. The contributions of wetting layer (WL), first excited state (ES1), and second excited state (ES2) have also been considered. Effect of WL−ES2 recombination time of both electrons and holes, carrier heating (CH) time of electrons and holes, in addition to electron hole recombination time are examined. The results show that there is a gap between electron and hole heating temperature due to the difference between there recovery times. It is found that fast hole (long electron) recombination time yield a high carrier temperature.
Intracardiac thrombosis following intravenous zoledronate treatment in a child with steroid-induced osteoporosis
Authors: Case Samantha J. , Moon Rebecca J. , Bharucha Tara , Davies Justin H.
Published: November 2022

Objectives

Bisphosphonates are used in childhood osteoporosis but can cause an acute phase reaction (APR) and hypocalcemia. We present a child with cardiac thrombosis following zoledronate, a previously unreported complication.

Case presentation

An 11-year-old with Duchenne muscular dystrophy and steroid-induced osteoporosis presented 48 h after first zoledronate infusion with fever, tachycardia, tachypnoea and hypoglycaemia. This was managed as acute adrenal crisis and possible sepsis. He also had hypocalcemia, hypophosphatemia, hyponatraemia and hypokalaemia. Echocardiography performed due to persistent chest pain and tachycardia revealed a left ventricular thrombus.

Conclusions

Potential causes for intracardiac thrombosis in this patient include ventricular dysfunction due to acute adrenal crisis or electrolyte disturbance, and hypercoagulability due to the APR. Echocardiography should be considered in children with acute cardiovascular compromise following zoledronate. Stress-dose steroids to cover the APR and a reduced starting dose of zoledronate might have reduced the risk of this complication.
Developing and contributing to systemic functional translation studies in China: an interview with Professor Guowen Huang
Authors: Huang Guowen , Wang Bo , Ma Yuanyi
Published: November 2022

Systemic functional translation studies (SFTS) has been a research area sustained by scholars from both Systemic Functional Linguistics (SFL) and translation studies over the past decades. In China, there have been an increasing number of studies in SFTS after the 2000s, with Professor Guowen Huang being one of the pioneering and influential scholars contributing to this emerging research area. This paper is a transcript of an interview conducted with Guowen Huang and it serves to provide a general introduction to his research. In the interview, he discusses his motivation for exploring SFTS, the advantages of applying SFL to translation studies, and the Ph.D. students he has supervised over the past decades. He also introduces his own work on the translations of ancient Chinese poems, the translations of the Analects (Lunyu 论语) of Confucius, and his investigation of applying ecolinguistics to translation studies. Finally, he suggests some future studies needed in this area.
Unum, Verum, Bonum and the System Formation of Critical Philosophy
Authors: Nakano Hirotaka
Published: November 2022

This article deals with Kant’s intentions in adding § 12 of the second edition of the Critique of Pure Reason. Here, Kant remarks on the so-called transcendentals (unum, verum, bonum) in the metaphysical or ontological tradition. This article focuses on their trans-categorial character to clarify their role in the system formation of Kant’s three critiques. In order to clarify Kant’s difficult terminology in § 12, fragments from his reflections and transcripts of his lectures are analyzed. Furthermore, an examination of Kant’s references to qualitative unity, plurality, and perfection reveals that these logical criteria of cognition in general help him to organize the content of the three critiques.
Mechanical and heat transfer properties of 4D-printed shape memory graphene oxide/epoxy acrylate composites
Authors: Xu Jinghang , Chen Long , Yang Xue , Liu Zhanqiang , Song Qinghua
Published: November 2022

4D printing is a new technology to fabricate active smart materials, which can change the configuration according to environmental stimuli. To obtain shape memory graphene oxide/bisphenol A epoxy acrylate (GO/Bis-A EA) composites with outstanding shape memory properties and significant thermal conductivity, GO was introduced into Bis-A EA to prepare shape memory GO/Bis-A EA composites by light curing. Through the shape recovery and heat transfer experiments, the shape recovery rate and heating rate were tested to characterize the shape memory and heat transfer performance. The relationship between various influencing factors and the properties of composites were investigated, and the optimal fitting model was established to optimize the preparation process by setting shape recovery rate and heating rate as response values. The results showed that when the content of diphenyl (2,4,6-trimethylbenzoyl) phosphine oxide was 4.4%, 1,6-hexanediol diacrylate/Bis-A EA was 0.6, curing power was 40 W, GO content was 0.05%, and curing time was 14 s, the shape recovery rate of the experiments was 87.22% with the heating rate being 0.1532°C/s. The predicted values of shape recovery rate and heating rate inferred by the response surface optimization model were 86.35% and 0.1520°C/s, respectively, which were within 2% error. Through the process optimization research, the 4D-printed shape memory GO/Bis-A EA can achieve excellent shape recovery and heat transfer performance to meet the application of shape memory composites in extreme environments.
American Spanish dizque from a Functional Discourse Grammar perspective
Authors: Olbertz Hella
Published: November 2022

This article discusses the diachronic development and the different uses of the reportative word dizque (diachronically based on diz que ‘she/he/it says that’) using data from Colombian and Mexican Spanish. The study presents a predominantly qualitative analysis of diachronic, twentieth- and twenty-first-century written data. The theoretical framework applied in this article is Functional Discourse Grammar (FDG), which is particularly useful in this context as it distinguishes between the interpersonal and representational functions of language. The main points made are: (i) dizque is an adverb that arose from a process of lexicalization rather than grammaticalization; (ii) in most of its uses, dizque has an interpersonal function in the sense that the Speaker instructs the Addressee that she/he is not the source of the information provided; (iii) by means of diachronic, dialectal, and typological data, it is shown that the scope of dizque is gradually decreasing; (iv) the only scope decrease that leads to a functional change of dizque is its application outside the context of speech-reports. FDG serves to account for each step in the scope decrease of dizque by means of its hierarchical approach to the actional and descriptive functions of verbal interaction.
Modification in Functional Discourse Grammar: State of the art and issues addressed
Authors: Keizer Evelien , Schwaiger Thomas , ten Wolde Elnora
Published: November 2022

This is an introduction to the Special Issue on Modification in Functional Discourse Grammar.
Ethnic networks in the internationalization of Turkish food producers
Authors: Bagci Utku Eren , Franz Martin , Yavan Nuri
Published: November 2022

The Uppsala Internationalization Process Model falls short in its ability to explain how emerging market firms internationalize. In this respect, the model needs to be enhanced through theoretical and empirical contributions. In this study, we aimed to increase the relationality of the model by employing the ethnic networks approach. As a case study for emerging market companies, we focused on the internationalization processes of Turkish food companies, which have been relatively little studied until now. Based on data from qualitative interviews, we found that ethnic networks in Germany play an important role in the initial stages of export activities, in location selection, in gaining market information, and in reaching the mainstream retailers and consumers for Turkish food companies. Adopting the ethnic networks approach enables us to see the roles of previously ignored relationships. Our findings show that, in future research, the role of ethnic networks should not be overlooked in the process of applying the Uppsala Internationalization Process Model on emerging market firms.
From maximum force to physics in 9 lines and towards relativistic quantum gravity
Authors: Schiller Christoph
Published: November 2022

A compact summary of present fundamental physics is given and evaluated. Its 9 lines describe all observations exactly and contain both general relativity and the standard model of particle physics. Their precise agreement with experiments, in combination with their extreme simplicity and their internal consistency, suggest that there are no experimental effects beyond the two theories. The combined properties of the 9 lines also imply concrete suggestions for the microscopic constituents in a complete theory of relativistic quantum gravity. It is shown that the microscopic constituents cannot be described by a Lagrangian or by an equation of motion. Finally, the 9 lines specify the only decisive tests that allow checking any specific proposal for such a theory.
Capital social y su vínculo con la pobreza en Costa Rica
Authors: Collado Andrea
Published: November 2022

Este artículo explora algunas de las relaciones teóricas y empíricas entre el capital social y la pobreza en Costa Rica. Se define "capital social" como el valor de las relaciones sociales mediadas por "normas de reciprocidad". Se usan datos de la encuesta de Opinión Pública de América Latina (2004) y del Censo de Población y Vivienda (2000). Se comprobó que la pobreza disminuye, conforme aumenta el capital social. Los estratos bajos y altos participan más en organizaciones formales e informales que el estrato medio. Las zonas urbanas tienen una menor probabilidad de ser pobres, en comparación con los barrios rurales. Sin embargo, las áreas rurales posen más capital social. Investigaciones futuras deben tratar de mejorar las mediciones de capital social, estudiar a fondo las organizaciones y redes donde participan los pobres y profundizar en los tipos del capital social que contribuyen a disminuir la pobreza en el país.
Economía, sociedad y ambiente
Authors: Huaylupo Alcázar Juan
Published: November 2022

El presente ensayo analiza críticamente la concepción dominante de la economía. Esta ciencia es generalmente concebida como una ciencia exacta y universal. Esto produce que se dogmaticen las teorías y tiendan a aplicarse de manera estandarizada. Ejemplos de ello ocurren cuando se abordan los temas relacionados con el crecimiento económico y la maximización de las ganancias. La consecuencia de este enfoque es que se transfigura la comprensión y explicación de la ciencia económica, para hacer de la economía una técnica absoluta, comprometida políticamente y con pretensiones de modelar las relaciones sociales al margen de la historia, cultura y organización de los pueblos y sociedades. La economía, siendo un resultado de complejas interrelaciones sociales, ha sido transformada en subsidiaria de modelos "teóricos", técnicos o matemáticos. Esto es, se reduce y simplifica los procesos sociales a cuantificaciones y relaciones econométricas como si estos recursos formales pudieran ser válidos como diagnosis y prognosis de las realidades. La renuncia a la comprensión y explicación de los fenómenos económicos, ha transformado a la economía en una disciplina funcional a las relaciones económicas y poderes predominantes. Por ello, muchos economistas son justificadores, asesores o ideólogos de las prácticas económicas del poder político, empresarial y trasnacional. Este ensayo retoma una rica perspectiva analítica que articula lo económico a las relaciones políticas, históricas y culturales específicas de los espacios sociales donde se producen e intercambian mercancías. Asimismo, adopta una posición para la reconversión científica y crítica de la teoría económica actual.
Actores sociales y relaciones de poder: la globalización como proceso y fenómeno socio-político
Authors: Paulino Vargas Luis
Published: November 2022

La idea dominante acerca de la globalización -así elaborada desde la ideología neoliberal- la presenta como un proceso inevitable, que se despliega y avanza al margen de toda voluntad humana. Esta concepción, sin embargo, posee un estatuto metafísico, no científico. En cambio, admitir el carácter social y político de la globalización, es decir, el hecho de que ésta es simplemente resultante del pensamiento, las acciones y decisiones de seres humanos que interactúan de forma compleja, implica admitir que la globalización no es más evitable o inevitable de lo pueda ser cualquier fenómeno humano. Este artículo diserta teóricamente sobre esta problemática, e intenta desarrollar, en sus aspectos más generales, una elaboración teórica que haga inteligibles las categorías principales de actores y el entramado sistémico a que las interrelaciones entre esos actores da lugar, todo lo cual constituye, a fin de cuentas, las fuerzas sociales -y por lo tanto humanas- que subyacen a la globalización.
Desarrollos geotérmicos en parques nacionales, una posibilidad constitucional
Authors: Campos Vargas Henry
Published: November 2022

En este artículo, sostenemos que la generación geotérmica de electricidad respeta el ordenamiento constitucional costarricense, así como sus compromisos internacionales y su derecho interno
La cultura y el proceso de globalización en el desarrollo de las pequeñas y medianas empresas latinoamericanas
Authors: Arroyo Venegas Isabel Cristina
Published: November 2022

No cabe duda de que el sector de las pequeñas y medianas empresas (Pymes) de todos los países latinoamericanos está en un obligado crecimiento y con urgentes necesidades debido a los cambios veloces que desde todos los ámbitos se están generando, por las fuertes concentraciones de la riqueza en muy pocos grupos y el crecimiento acelerado del número de personas en condiciones de extrema pobreza. Si bien existen importantes iniciativas y esfuerzos, a nivel de algunos gobiernos y varios grupos organizados de la sociedad, para impulsar y fortalecer el desarrollo de este sector, es claro que su entorno sigue impregnado de incertidumbre y pesimismo porque el proceso de apertura comercial continúa extendiéndose sin considerar las prioridades y condiciones de cada nación. En congruencia con lo anterior, en este artículo se presenta un estudio y análisis que demuestra el impacto que han tenido la cultura y el proceso de globalización en el desarrollo de las Pymes latinoamericanas y una propuesta de apoyo a este sector con ideas para los distintos grupos de actores involucrados: gobiernos, organizaciones de apoyo, instituciones financieras, escuelas de negocios de las universidades y Pymes.