bluuebunny/crossref_metadata_2025 huggingface dataset:
Pulsed Electric Field Induces Significant Changes in the Metabolome of Fusarium Species and Decreases Their Viability and Toxigenicity
Authors: Behner Adam , Palicova Jana , Tobolkova Anna-Hirt , Prusova Nela , Stranska Milena
Published: January 2025

Fusarium fungi are widespread pathogens of food crops, primarily associated with the formation of mycotoxins. Therefore, effective mitigation strategies for these toxicogenic microorganisms are required. In this study, the potential of pulsed electric field (PEF) as an advanced technology of increasing use in the food processing industry was investigated to minimize the viability of Fusarium pathogens and to characterize the PEF-induced changes at the metabolomic level. Spores of four Fusarium species (Fusarium culmorum, Fusarium graminearum, Fusarium poae, and Fusarium sporotrichioides) were treated with PEF and cultured on potato dextrose agar (PDA) plates. The viability of the Fusarium species was assessed by counting the colony-forming units, and changes in the mycotoxin content and metabolomic fingerprints were evaluated by using UHPLC-HRMS/MS instrumental analysis. For metabolomic data processing and compound identification, the MS-DIAL (v. 4.80)–MS-CleanR–MS-Finder (v. 3.52) software platform was used. As we found out, both fungal viability and the ability to produce mycotoxins significantly decreased after the PEF treatment for all of the species tested. The metabolomes of the treated and untreated fungi showed statistically significant differences, and PEF-associated biomarkers from the classes oxidized fatty acid derivatives, cyclic hexapeptides, macrolides, pyranocoumarins, carbazoles, and guanidines were identified.
Mapping Variability of Mycotoxins in Individual Oat Kernels from Batch Samples: Implications for Sampling and Food Safety
Authors: Teixido-Orries Irene , Molino Francisco , Castro-Criado Bianca , Jodkowska Monika , Medina Angel , Marín Sonia , Verheecke-Vaessen Carol
Published: January 2025

Oats are susceptible to contamination by Fusarium mycotoxins, including deoxynivalenol (DON), zearalenone (ZEN), and T-2/HT-2 toxins, posing food safety risks. This study analyses the variation in levels of 14 mycotoxins in 200 individual oat kernels from two DON-contaminated batch samples (mean = 3498 µg/kg) using LC-MS/MS. The samples also contained deoxynivalenol-3-glucoside (DON-3G), 3-acetyldeoxynivalenol (3-ADON), 15-acetyldeoxynivalenol (15-ADON), and ZEN. Contamination levels varied notably among individual kernels, with DON detected in 70% of them, followed by DON-3G (24.5%) and 3-ADON (20.5%). Importantly, 8% of kernels exceeded the EU legal limit for DON (1750 µg/kg), and some occasionally surpassed limits for ZEN and T-2/HT-2. Correlation analyses revealed strong associations between DON and its derivatives but weaker correlations with other toxins. Mycotoxin ratios varied widely, indicating that although they often co-occur, their concentrations differ between kernels. Contamination did not significantly impact kernel weight, though a slight trend toward lower weights in contaminated kernels was noted. Additionally, sampling statistics showed that as the percentage of selected kernels increased, the probability of batch sample rejection for DON contamination rose significantly. The study highlights the heterogeneity of mycotoxin contamination in oat batches, emphasising the importance of accurate detection and regulatory compliance to ensure safer oat-based products.
HDAC6 Facilitates PRV and VSV Infection by Inhibiting Type I Interferon Production
Authors: Zheng Hu , Yang Xiaohui , Zhong Haiwen , Song Changxu , Wu Zhenfang , Yang Huaqiang
Published: January 2025

HDAC6 modulates viral infection through diverse mechanisms. Here, we investigated the role of HDAC6 in influencing viral infection in pig cells with the aim of exploiting the potential antiviral gene targets in pigs. Using gene knockout and overexpression strategies, we found that HDAC6 knockout greatly reduced PRV and VSV infectivity, whereas HDAC6 overexpression increased their infectivity in PK15 cells. Mechanistic studies identified HDAC6 as a DNA damage inhibitor in PK15 cells. HDAC6 overexpression attenuated DNA damage levels, which can further reduce type I IFN production to promote viral infection. Conversely, HDAC6 deficiency can limit viral infection by increasing DNA damage-mediated type I IFN production. This work demonstrates that HDAC6 affects the infection process of multiple viruses by modulating type I IFN production, highlighting a regulatory role of HDAC6 linking host immune response and viral infection levels in pig cells.
COVID-19 and HIV: Clinical Outcomes and Inflammatory Markers in a Cohort from a Reference Hospital in Rio de Janeiro, Brazil
Authors: de Sá Nathalia Beatriz Ramos , Macieira Karine Venegas , Coelho Mariana Rosa Inacio , Goulart Milena Neira , Ribeiro-Alves Marcelo , Rosadas Leonardo Azevedo da Silva , Geraldo Kim Mattos , Ribeiro Maria Pia Diniz , Cardoso Sandra Wagner , Grinsztejn Beatriz , Veloso Valdiléa G. , Cazote Andressa da Silva , de Almeida Dalziza Victalina , Giacoia-Gripp Carmem Beatriz Wagner , Côrtes Fernanda Heloise , Morgado Mariza Gonçalves
Published: January 2025

Background: Severe COVID-19 presents a variety of clinical manifestations associated with inflammatory profiles. People living with HIV (PLWH) could face a higher risk of hospitalization and mortality from COVID-19, depending on their immunosuppression levels. This study describes inflammatory markers in COVID-19 clinical outcomes with and without HIV infection. Methods: We analyzed 112 inpatients of the Hospital Center for COVID-19 (INI/FIOCRUZ), including 22 cases of COVID-19 in PLWH (COVID/PLWH group). Plasma samples were tested for a panel of 15 cytokines by Luminex. Sociodemographic, clinical, and laboratory data were collected from patients’ clinical records. Results: COVID-19 individuals were stratified according to the WHO clinical severity profiles at hospitalization. Significant differences in clinical scores, symptoms (coughs), and the occurrence of HIV infection were found among the groups. Clinical blood parameters and plasma cytokines were analyzed among COVID-19 groups with distinct severity profiles. Critical COVID-19 cases showed higher levels of inflammatory markers (Bilirubin, D-dimer, PCR, and urea, as well as IL-8, IL-10, TNF-α, INF-α, IL-1β, IL-17A, IL-23, IL-6) than moderate and severe groups. The COVID/PLWH group had lower CD4 counts (64 cells/mm3) and cytokine levels than other COVID-19 patients. Conclusions: Overall, critically ill COVID-19 patients exhibited heightened inflammatory responses, while COVID/PLWH demonstrated unique immunological characteristics without increased mortality risk.
Use of ProMED as a Surveillance System for Emerging and Re-Emerging Infectious Diseases in Brazil from 2015 to 2020
Authors: Rocha Davi Carreiro , Santos Louro Luana , Ewald Oliveira Hosana , Cancian de Araujo Bruno , Ryu Sukhyun , Vicente Creuza Rachel
Published: January 2025

Emerging and re-emerging infectious diseases have been frequently reported in Brazil. The Program for Monitoring Emerging Diseases (ProMED) is a virtual system with expert curation for monitoring health events, including those occurring in Brazil. This study aimed to describe the ProMED as a complementary surveillance system for emerging infectious diseases in Brazil. It has a retrospective and descriptive design, and was conducted using ProMED-PORT reports that cited Brazil and were published from 1 January 2015, to 31 December 2020. In total, 220 new reports were identified during the study period. Most of these were published between January and June. Reports on humans were predominant (n = 177), and comprised 78 kinds of events, most of which were related to arboviruses. Reports on animals were the second most prevalent (n = 35), and encompassed 18 kinds of events, particularly yellow fever in non-human primates, rabies in different mammals, and sporotrichosis in felines. Six (2.7%) reports were related to humans and animals, while two (0.9%) were related to plants or the environment. Most reports were from Southeast and Northeast regions. ProMED identified leading emerging and reemerging infectious diseases in Brazil, serving as an information source for local and international health authorities.
Egyptian Novel Goose Parvovirus in Immune Organs of Naturally Infected Ducks: Next-Generation Sequencing, Immunohistochemical Signals, and Comparative Analysis of Pathological Changes Using Multiple Correspondence and Hierarchical Clustering Approach
Authors: Lebdah Mohamed A. , Eid Amal A. M. , ElBakrey Reham M. , El-Gohary Abd Elgalil. , Seadawy Mohamed G. , Mousa Mohamed R. , Gouda Hagar F. , Goda Nehal I. A. , El-Hosseny Mostafa F. , El-tahlawy Ahmed S. , Sami Rokayya , Al-Eisa Rasha A. , Helal Sarah S.
Published: January 2025

The present study aims to better understand the nature of currently circulating GPV strains and their pathological impact on the immune system during natural outbreaks among different duck breeds in Egypt. For this purpose, 99 ducks (25 flocks) of different breeds, aged 14–75 days, were clinically examined, and 75 tissue pools from the thymus, bursa of Fabricius, and spleen were submitted for virus detection and identification. Clinical and postmortem findings were suggestive of GPV infection. Concerning the immune system organs, atrophy in the thymus (60.6%), bursa (45.5%), and spleen (38.3%) was the most common gross lesion. Microscopically, the pathological impact of the virus was exhibited by a necrotic thymic cortex with Hassall’s corpuscle disintegration, the disappearance of normal bursal histological morphology accompanied by atrophied follicles and lymphocytic depletion, and apoptosis of B-lymphocytes in lymphoid follicles of the spleen. Furthermore, immunohistochemical examination revealed positive signals of the parvovirus detected in thymic lymphocytes in the cortex, bursa-dependent lymphoid follicle of the medulla, and diffuse positive expression of viral antigens in the spleen. GPV was detected in ducks using polymerase chain reaction, with the highest percentage of positive detection in the bursa of Fabricius (76%). Next-generation sequencing and phylogenetic analysis revealed that the detected virus was a variant of GPV, globally named novel GPV (NGPV), and closely related to Chinese NGPV isolates. To our knowledge, the current study is pioneering to address the immunopathological impact of NGPV among naturally infected ducks confirmed with full genome sequencing and immunohistochemical identification worldwide.
Role of the Psi Packaging Signal and Dimerization Initiation Sequence in the Organization of Rous Sarcoma Virus Gag-gRNA Co-Condensates
Authors: Lambert Gregory S. , Maldonado Rebecca J. Kaddis , Parent Leslie J.
Published: January 2025

Retroviral genome selection and virion assembly remain promising targets for novel therapeutic intervention. Recent studies have demonstrated that the Gag proteins of Rous sarcoma virus (RSV) and human immunodeficiency virus type-1 (HIV-1) undergo nuclear trafficking, colocalize with nascent genomic viral RNA (gRNA) at transcription sites, may interact with host transcription factors, and display biophysical properties characteristic of biomolecular condensates. In the present work, we utilized a controlled in vitro condensate assay and advanced imaging approaches to investigate the effects of interactions between RSV Gag condensates and viral and nonviral RNAs on condensate abundance and organization. We observed that the psi (Ψ) packaging signal and the dimerization initiation sequence (DIS) had stabilizing effects on RSV Gag condensates, while RNAs lacking these features promoted or antagonized condensation, depending on local protein concentration and condensate architecture. An RNA containing Ψ, DIS, and the dimerization linkage structure (DLS) that is capable of stable dimer formation was observed to act as a bridge between RSV Gag condensates. These observations suggest additional, condensate-related roles for Gag-Ψ binding, gRNA dimerization, and Gag dimerization/multimerization in gRNA selection and packaging, representing a significant step forward in our understanding of how these interactions collectively facilitate efficient genome packaging.
Live Plague Vaccine Development: Past, Present, and Future
Authors: Anisimov Andrey P. , Vagaiskaya Anastasia S. , Trunyakova Alexandra S. , Dentovskaya Svetlana V.
Published: January 2025

During the last 100 years, vaccine development has evolved from an empirical approach to one of the more rational vaccine designs where the careful selection of antigens and adjuvants is key to the desired efficacy for challenging pathogens and/or challenging populations. To improve immunogenicity while maintaining a favorable reactogenicity and safety profile, modern vaccine design must consider factors beyond the choice of target antigen alone. With new vaccine technologies currently emerging, it will be possible to custom-design vaccines for optimal efficacy in groups of people with different responses to vaccination. It should be noted that after a fairly long period of overwhelming dominance of papers devoted to subunit plague vaccines, materials devoted to the development of live plague vaccines have increasingly been published. In this review, we present our opinion on reasonable tactics for the development and application of live, safe, and protective human plague vaccines causing an enhanced duration of protection and breadth of action against various virulent strains in vaccination studies representing different ages, genders, and nucleotide polymorphisms of the genes responsible for immune response.
Efficacy of Anti-Cancer Immune Responses Elicited Using Tumor-Targeted IL-2 Cytokine and Its Derivatives in Combined Preclinical Therapies
Authors: Balkhi Sahar , Bilato Giorgia , De Lerma Barbaro Andrea , Orecchia Paola , Poggi Alessandro , Mortara Lorenzo
Published: January 2025

Effective cancer therapies must address the tumor microenvironment (TME), a complex network of tumor cells and stromal components, including endothelial, immune, and mesenchymal cells. Durable outcomes require targeting both tumor cells and the TME while minimizing systemic toxicity. Interleukin-2 (IL-2)-based therapies have shown efficacy in cancers such as metastatic melanoma and renal cell carcinoma but are limited by severe side effects. Innovative IL-2-based immunotherapeutic approaches include immunotoxins, such as antibody–drug conjugates, immunocytokines, and antibody–cytokine fusion proteins that enhance tumor-specific delivery. These strategies activate cytotoxic CD8+ T lymphocytes and natural killer (NK) cells, eliciting a potent Th1-mediated anti-tumor response. Modified IL-2 variants with reduced Treg cell activity further improve specificity and reduce immunosuppression. Additionally, IL-2 conjugates with peptides or anti-angiogenic agents offer improved therapeutic profiles. Combining IL-2-based therapies with immune checkpoint inhibitors (ICIs), anti-angiogenic agents, or radiotherapy has demonstrated synergistic potential. Preclinical and clinical studies highlight reduced toxicity and enhanced anti-tumor efficacy, overcoming TME-driven immune suppression. These approaches mitigate the limitations of high-dose soluble IL-2 therapy, promoting immune activation and minimizing adverse effects. This review critically explores advances in IL-2-based therapies, focusing on immunotoxins, immunocytokines, and IL-2 derivatives. Emphasis is placed on their role in combination strategies, showcasing their potential to target the TME and improve clinical outcomes effectively. Also, the use of IL-2 immunocytokines in “in situ” vaccination to relieve the immunosuppression of the TME is discussed.
Computed Tomography Evaluation of Morphological Types of Femoral Trochlear Dysplasia in Small-Breed Dogs—A Retrospective Study
Authors: Garnoeva Radka S.
Published: January 2025

Abnormal trochlear morphology is one of the most important factors for patellar luxation occurrence in dogs, yet no studies have investigated its prevalence in the general population. This retrospective computed tomography study was designed to evaluate the trochlear groove morphology in four small dog breeds and the prevalence of trochlear dysplasia types according to Déjour’s classification depending on the breed, sex, and medial patellar luxation (MPL) presence and grade. A total of 174 joints (68 healthy, 96 grade II MPL, and 10 grade III MPL) from Mini-Pinschers, Yorkshire Terriers, Pomeranians, and Chihuahuas were included in the study. The morphological type of trochlear dysplasia (TD) was evaluated on axial scans and 3D reconstruction images according to the four-type classification of Déjour, sulcus angle, trochlear depth, and lateral/medial inclination angles. Of all 174 joints, 140 had trochlear dysplasia—all joints with MPL (n = 106) and 50% of healthy joints (n = 34). The classification of Déjour for trochlear dysplasia types (A, B, C, and D) corresponds to the morphology of the femoral trochlea in the studied small breeds of dogs. The results demonstrated three types of trochlear dysplasia according to Déjour: most commonly, type A, followed by type C, and most infrequently, type D. The Déjour type B was an incidental finding. The large proportion of clinically healthy joints with TD (50%) emphasises the significance of early trochlear morphology evaluation for the orthopaedical health of dogs from susceptible breeds, especially in female breeders.
Pathophysiology of Penetrating Captive Bolt Stunning in Horned and Polled Sheep and Factors Determining Incomplete Concussion
Authors: Gibson Troy John , Ridler Anne Lisa , Limon Georgina , Lamb Christopher , Williams Alun , Gregory Neville George
Published: January 2025

Penetrating captive bolt (PCB) is widely used for stunning and on-farm dispatch of livestock, yet its efficacy can vary, with the potential for animal welfare compromise. This study investigated the pathophysiology of PCB-induced trauma in horned and polled sheep (Ovis aries), focusing on factors contributing to incomplete concussion. Thirty-seven (n = 18 horned Scottish blackface and n = 19 polled North Country mule) mature ewes (aged 4–10 years) were shot with PCB with varying cartridge power and PCB modifications, followed by clinical assessment and post-mortem analysis using magnetic resonance imagining (MRI) and gross pathology. The results indicated that damage to the reticular activating system, bolt velocity and penetration depth are crucial for inducing irreversible unconsciousness, with depths less than 37 mm often resulting in incomplete concussion. MRI provided detailed insights into brain injuries, aligning well with gross pathological findings. This study highlights the importance of precise bolt placement and appropriate PCB configurations in ensuring humane outcomes, with MRI proving to be a valuable tool for assessing brain trauma in stunned animals. These findings enhance the understanding of effective stunning techniques and support improved welfare practices in livestock management.
Application of Homogenization Method in Free Vibration of Multi-Material Auxetic Metamaterials
Authors: Gunaydin Kadir , Gülcan Orhan , Tamer Aykut
Published: January 2025

Different additive manufacturing modalities enable the production of multi-material components which can be used in a wide range of industrial applications. The prediction of the mechanical properties of these components via finite element modelling rather than through testing is critical in terms of cost and time. However, due to the higher computational time spent on the modelling of lattice structures, different methods have been investigated to accurately predict mechanical properties. For this purpose, this study proposes the use of a homogenization method in the two most common types of multi-material lattices: honeycomb and re-entrant auxetics. Modal analyses were performed, and the first six mode shapes were extracted from explicit and implicit models. The results were compared in terms of mode shapes and natural frequencies. The results showed that homogenization can be successfully applied to multi-material honeycomb and re-entrant auxetic lattices without compromising the accuracy. It was shown that the implicit models predict the natural frequencies with an error range of less than 6.5% when compared with the explicit models in all of the mode shapes for both honeycomb and re-entrant auxetic lattices. The Modal Assurance Criteria, which is an indication of the degree of similarity between the mode shapes of explicit and implicit models, was found to be higher than 0.996, indicating very high similarity.
The Ellipsoid Zone Is a Structural Biomarker for Visual Outcomes in Diabetic Macular Edema and Macular Hole Management
Authors: Chaturvedi Shivani , Paul Amisha , Singh Samya , Akduman Levent , Saxena Sandeep
Published: January 2025

Objectives: The goal was to study the ellipsoid zone (EZ) as a structural biomarker for final visual outcomes after pharmacological intervention in center-involving diabetic macular edema (DME) and surgical intervention for full-thickness macular holes (FTMHs). Methods: This was a tertiary care center-based retrospective study. After sample size calculations, data from 64 consecutive cases were collected, with subjects aged between 40 and 60 years. Thirty-two cases of DME with anti-vascular endothelial growth factor (VEGF) therapy and 32 cases of FTMHs with successful macular hole surgery (MHS) were studied. Spectral-domain optical coherence tomography (SD-OCT) data were collected. Measurements of EZ defects documented at the time of presentation and 12 weeks after intervention were analyzed using the caliper function of the machine. EZ restoration was graded, and a Pearson correlation analysis was performed. Results: Mean logMAR VA decreased after intravitreal therapy (IVT) from 1.12 ± 0.22 pre-intervention to 0.81 ± 0.41 post-intervention and after MHS, from 1.05 + 0.25 to 0.62 + 0.11 (p < 0.001). EZ disruption reduced from 73.4% to 19.4% after IVT and from 67% to 19.3% after MHS. DME and MHS postoperative visual acuity and residual EZ defect were observed to have a statistically significant linear correlation (r = 0.794, p < 0.001 and r = 0.894, p < 0.001, respectively). The EZ was found to be an excellent structural biomarker for final BCVA (area under curve = 0.95 for DME and 1.00 for MHS). Conclusion: Notable EZ restoration results were obtained from pharmacological and surgical interventions. The EZ proves to be a critical structural biomarker for predicting visual outcomes in center-involving DME and MHS.
The Optimization of River Network Water Pollution Control Based on Hydrological Connectivity Measures
Authors: Bu Jiuhe , Li Chunhui , Xu Tian , Wang Tao , Da Jinrong , Li Xiaoyun , Chen Hao , Song Weixin , Sun Mengjia
Published: January 2025

Urbanization, driven by socio-economic development, has significantly impacted river ecosystems, particularly in plain city regions, leading to disruptions in river network structure and function. These changes have exacerbated hydrological fluctuations and ecological degradation. This study focuses on the central urban area of Changzhou using a MIKE11 model to assess the effects of four hydrological connectivity strategies—water diversion scheduling, river connectivity, river dredging, and sluice connectivity—across 13 different scenarios. The results show that water diversion, river dredging, and sluice connectivity scenarios provide the greatest improvements in water environmental capacity, with maximum increases of 54.76%, 41.97%, and 25.62%, respectively. The spatial distribution of improvements reveals significant regional variation, with some areas, particularly in Tianning and Zhonglou districts, experiencing declines in environmental capacity under sluice diversion and river-connectivity scenarios. In addition, the Lao Zaogang River is identified as crucial for improving the overall water quality in the network. Based on a multi-objective evaluation, combining environmental and economic factors, the study recommends optimizing water diversion scheduling at sluices (Weicun, Zaogang, and Xiaohe) with flow rates between 20–40 m3/s, enhancing connectivity at key river hubs, and focusing management efforts on the Lao Zaogang and Xinmeng rivers to strengthen hydrological and water quality linkages within the network.
Development of Deep Learning-Based Algorithm for Extracting Abnormal Deceleration Patterns
Authors: Jun Youngho , Kim Minha , Lee Kangjun , Woo Simon S.
Published: January 2025

A smart regenerative braking system for EVs can reduce unnecessary brake operations by assisting in the braking of a vehicle according to the driving situation, road slope, and driver’s preference. Since the strength of regenerative braking is generally determined based on calibration data determined during the vehicle development process, some drivers could encounter inconveniences when the regenerative braking is activated differently from their driving habits. In order to solve this problem, various deep learning-based algorithms have been developed to provide driving stability by learning the driving data. Among those artificial intelligence algorithms, anomaly detection algorithms can successfully separate the deceleration data in abnormal driving situations, and the resulting refined deceleration data can be used to train the regression model to achieve better driving stability. This study evaluates the performance of a personalized driving assistance system by applying driver characteristic data, obtained through an anomaly detection algorithm, to vehicle control.
Expressive means, the «matter» of art and artistic form
Authors:   Sector of Interdisciplinary Problems of Scientific and Technological Development, Institute of Philosophy, Russian Academy of Sciences, Rozin Vadim Markovich
Published: January 2025

The author shows that artistic reality is created, and not only lived and perceived as a
naturally existing artistic world and events. It is created on the basis of specifi c semiotic
matter (sounds, words, colors, etc.), expressive means (ideas about melody, harmony,
rhythm, themes, drama, form-composition, and so on; these means diff er for diff erent types of art), and artistic form. The author proves that despite the fact that at fi rst glance
it seems that the matter of art is the main, there are still many conditions for the perception
of musical sound: we hear not the vibrations of the auditory nerve, but the musical
tone, theme, and melody. The auditory image, the whole, arises as a result of the meeting
of sonorous information and the actualization of our “experience of hearing” (Helmholtz).
The latter is formed on the basis of many components: actual live listening to music, the
implementation of knowledge, and comprehension.
Patriotic project in the student space
Authors:   Department of General Humanities and Mass Communications, Moscow International University, Department of Sociology and Media Communications, Federal State Budgetary Educational Institution of Inclusive Higher Education Russian State University of Social Technologies, Nazmetdinova Irina Sayranovna
Published: January 2025

The article presents signifi cant events of the patriotic project “Memory of Generations”,
implemented at the Federal State Budgetary Educational Institution of Inclusive Higher
Education “Russian State University of Social Technologies” together with the State Budgetary
Educational Institution School No. 1795
Camaronicultura en Colombia, estado actual, retos y oportunidades
Authors: Porto Fragozo Pedro Luis , Cervera Cahuama Sigifredo José , Albis Arrieta Alberto Ricardo , Rodriguez Forero Adriana
Published: January 2025

La producción de camarón en Colombia marcó un hito muy importante en la acuicultura del país en la década de los 90 y principios del 2000, llegando a aportar a la economía del país alrededor de USD$51.000.000. Sin embargo, varios aspectos fundamentales como la aparición de patógenos, la revaluación del peso colombiano, entre otros, ocasionaron una eventual caída en la producción no solo en el país sino también a nivel mundial. La reactivación de la industria se ha visto afectada, principalmente por la fuerte competencia en los mercados internacionales debido a la baja productividad resultante de la escasa tecnología utilizada en sistemas de producción sostenibles, así como por la implementación de nuevas fuentes de alimentación para el cultivo de este crustáceo. En este documento se exploran los desafíos y retos históricos y actuales en la producción del camarón Penaeus vanammei en Colombia.
Paginas Preliminares del Vol 5 No. 2
Authors: Editorial Equipo
Published: January 2025

Portada
Patrocinantes
Créditos de esta edición
Contenido
Páginas Preliminares del Vol. 5 No. 3
Authors: Editorial Equipo
Published: January 2025

Portada
Portada del Vol. 5 No. 3 Composición formada por las fotografías del II PhotoFIRMA que llevan por título: "Atardecer en la granja" de Alexander Valera Mejías, "Apaguen la luz" de Bernardo Battaglia Aljaro, "Alevines clasificación y traslado" de Ana Laura Anzueto Herrera, "Academia de Alto Nivel" de María Mercedes Espinoza Vera, "Arte de la Naturaleza" de Adrián José Márquez Montiel tercer lugar.
Patrocinantes:
Esta publicación es patrocinada por:
Megasupply   que es un socio estratégico que contribuye generando valor en la distribución de equipos, suministros, alimentos, probióticos, químicos y servicios en general en todo lo relacionado a la industria acuícola.
North American Renderers Association  que trabaja para promover un mayor y más eficaz uso de los productos de origen animal al organizar seminarios educativos y delegaciones comerciales, patrocinar investigación y diseminar la información comercial y técnica en todo el mundo.
Foro Iberoamericano de los Recursos Marinos y la Acuicultura (FIRMA),  que es un foro anual que gestiona capacitación, difusión y discusión sobre de ciencia y tecnología para el desarrollo sostenible en el aprovechamiento de los recursos acuáticos y la acuicultura.
Créditos de esta edición
Contenido
DEVELOPING RIVER WATERSHEDS INTO TOURISM DESTINATIONS WITH AN ENVIRONTMENT BASED TOURISM (ECOPTOURISM) APPROACH: A CASE STUDY FROM SUNTENJAYA TOURISM VILLAGE, INDONESIA
Authors: Rachmat Syam
Published: January 2025

Rural areas, especially those that are river basins, are very vulnerable to destructive changes from various activities, including tourism. This is also indicated as happening in the Suntenjaya Tourism Village, Indonesia. Therefore, it is necessary to study the application of ecotourism to mitigate the negative impacts of tourism on Cikapundung watershed conservation. The application of ecotourism to nature tourism activities in Suntenjaya Village was studied through descriptive research with a qualitative approach. Through observation, interviews, and secondary data collection, it was found that ecotourism has only been partially applied to nature tourism activities in Suntenjaya Tourism Village. The application of ecotourism can be promoted through the sustainable development orientation of Pokdarwis, but it is hindered by social conflicts and organizational duality in Suntenjaya Tourism Village
Implementation of Environtmentally Friendly Exhibition Booths by PT. City Neonindo Indah Murni
Authors: Sa'diyah Halimatus
Published: January 2025

In contemporary society, the imperative to reduce carbon footprints and mitigate other environmental impacts has become increasingly paramount. Businesses and industries are under mounting pressure to innovate and incorporate environmentally friendly practices across all sectors, including those historically perceived as less eco-friendly, such as exhibition stands. This research examines the perspective of PT City Neonindo Indah Murni, a leading exhibition stand contractor, regarding environmentally conscious exhibition stand design. The primary focus of this study is to investigate the utilization of environmentally friendly materials in exhibition stand construction. It is anticipated that the research findings will make a significant contribution to the general development of environmentally sustainable exhibition stands, which can be widely applied in exhibitions and by other stand contractors. The research methodology employs a qualitative descriptive approach. Data collection processes involve interviews, observations, documentation studies, and literature reviews. As a final step, the data analysis process will utilize an interactive model approach, subsequently validated through source triangulation to verify the validity of the research conclusions. Based on the data collection steps undertaken, it can be posited that PT City Neonindo Indah Murni, as one of Indonesia's preeminent stand contractors, has demonstrated efforts to utilize more environmentally friendly materials and implement reuse concepts for certain components. However, there remains scope for improvement through further research into the exploration of alternative materials such as bamboo, recycled fiberboard, or other eco-friendly composite materials, as well as the development of more efficient and environmentally friendly modular construction methods.
Pengaruh Aksesibilitas Terhadap Keputusan Berkunjung di Chevilly Resort and Camp
Authors: Sam Samuel , Raidah Zhafirah Febrianti
Published: January 2025

Accessibility is an important aspect of tourist destinations that makes it easier for visitors to travel. Accessibility also influences visitors' desire to visit tourist destinations. Easy, adequate access and connected to public infrastructure services such as gas stations, minimarkets and others will influence tourists' interest in coming. The purpose of this research is to determine the influence of accessibility on the decision to visit Chevilly Resort and Camp.
This research uses quantitative methods with a sample of 109 visitors. This sampling technique uses accidental sampling. The data analysis method used is simple linear regression which includes validity test, reliability test, normality test, T test and coefficient of determination test ¬(R2). The author uses quantitative descriptive methods with data analysis using IBM SPSS Statistics 26.
The research results show that accessibility influences the decision to visit with the results being 72.9% influenced by this variable and the remainder influenced by other variables not examined in this research. The conclusion is that accessibility has a significant influence on the decision to visit through the ease of access provided by the Chevilly Resort and Camp to meet visitors' travel needs.
Optimizing Promotion and Service Quality in Influencing Purchase Decisions in the Tourism Sector
Authors: Hari Rachmadi  , Fuadi Afif  , Hermadistha Dheanova
Published: January 2025

This research examines the influence of promotion and service quality on purchase decisions for tourism products at Wuki Travel Jogja. Using a quantitative approach, a survey was conducted with 100 respondents who had previously used Wuki Travel Jogja's services. The study employed various analytical techniques, including validity and reliability testing, as well as multiple regression analysis to examine the impact of the independent variables (promotion and service quality) on the dependent variable (purchase decision). The results indicate that both promotion and service quality have a significant and positive influence on purchase decisions when analyzed simultaneously. However, when analyzed separately, promotion was found to have a more dominant effect, with a coefficient value of 0.897, compared to service quality, which showed no significant impact. The study concludes that improving promotional strategies may have the most substantial effect on influencing customer purchase decisions, while service quality, though important, may not play as significant a role in isolation
Implementation of Sustainable Development Goals (SDGs) Indicators at Makassar International Eight Festival & Forum 2023 by PT Festival Delapan Indonesia
Authors: Rizky Ady Satria Mulya  , Firman Karim Muhammad , Syafruddin
Published: January 2025

Sustainable Event are currently being echoed at this time, especially with the statement that events that produce negative impacts cannot be continued. One of the events that concern for the environment is Makassar International Eight Festival & Forum 2023. This research aims, To assess the extent to which the concept of sustainable event management has been implemented. The sustainability indicators used in this research are guided by the Sustainable Development Goals (SDGs) which have 17 global goals including, No Poverty, Zero Hunger, Good Health and Well-Being , Quality Education, Gender Equality, Clean Water and Sanitation, Affordable and Clean Energy, Decent Work and Economic Growth, Industry, Innovation and Infrastructure, Reduced Inequalities, Sustainable Cities, and Communities,  Responsible Consumption and Production, Climate Action, Life Below Water, Life on Land, Peace, Justice and Strong Institutions, Partnership For the Goals.  In this research the author used qualitative research methods. The data collection techniques in this research are interviews, document analysis and documentation. Informants in the research consisted of the main director and visitors to the Makassar International Eight Festival & Forum 2023. The results of this research show that there is one global goal of the Sustainable Development Goals (SDGs), namely SDGs 2 Zero Hunger, which has not been implemented. The 16 global SDGs goals have been implemented. Apart from that, the efforts made by the organizers also need to be increased to support sustainable events.
Key Words : Festival, Sustainable Development Goals;Sustainable Event;Management ;Sustainability
Pelibatan Masyarakat dalam Festival Tujuh Sungai
Authors: Raga Marsianus , Annisa Balqis , Syahril Lalu , Devania Keisya , Navaz Maria
Published: January 2025

Kesuksesan penyelenggaraan suatu festival dapat diukur dari seberapa terlibatnya masyarakat dalam mendukung dan membantu perencanaan, persiapan, serta pengadaan festival tersebut. Tanpa pelibatan masyarakat, kemungkinan festival untuk berjalan dengan lancar sangat kecil. Desa Cibuluh telah menyelenggarakan Festival Tujuh Sungai sejak 2015. Penyelenggaraan Festival Tujuh Sungai tentunya tidak luput dari pelibatan masyarakat. Penelitian ini bertujuan untuk meneliti sejauh mana pelibatan masyarakat dalam penyelenggaraan Festival Tujuh Sungai dan memberikan masukan untuk penyelenggara agar dapat meningkatkan pelibatan masyarakat. Fokus utama yang digunakan dalam penelitian ini yaitu keterlibatan sekolah; kesempatan menjadi sukarelawan; partisipasi dalam pengambilan keputusan; aksesibilitas; dan kerja sama bisnis. Metodologi penelitian yang digunakan adalah metode penelitian kualitatif, karena peneliti melakukan wawancara dengan hasil yang berbentuk deskriptif, teknik penentuan sampel purposive sampling dan snowball sampling, serta teknik kumpul data wawancara tidak terstruktur pada key informan dan kumpul data studi pustaka dan dokumentasi, yang kemudian dianalisis menggunakan teknik triangulasi. Hasil yang disimpulkan dari data penelitian menyatakan bahwa Festival Tujuh Sungai sudah sangat melibatkan masyarakat namun terdapat inovasi-inovasi yang dapat diterapkan untuk memajukan kualitas dari pelibatan tersebut.
Pengembangan Potensi Atraksi Pariwisata Berbasis Masyarakat
Authors: Izzatulmumtaz Nazhara , Muhammad Walid  , Ristiyanti Dwi Anggraini  , Reyhan Hartanto Akbar
Published: January 2025

PPenelitian ini membahas dampak signifikan pariwisata terhadap aspek sosial dan ekonomi masyarakat di Indonesia, terutama dengan potensi pariwisata yang melimpah dari kekayaan alam dan budaya yang beragam. Indonesia, sebagai negara berkembang dengan keragaman suku, adat istiadat, dan kebudayaan, memiliki daya tarik utama bagi wisatawan yang didukung oleh sumber daya alam yang melimpah. Undang-Undang Nomor 10 Tahun 2009 mengatur pariwisata sebagai sektor strategis dalam pembangunan ekonomi nasional. Desa Cibuntu, sebagai contoh wilayah dengan potensi pariwisata, dianalisis dalam konteks geografis dan iklimnya. Penelitian ini menggunakan metode kualitatif dengan pendekatan deskriptif dan metode kepustakaan, dengan teknik pengumpulan data berupa wawancara mendalam dan analisis dokumen. Hasil penelitian menunjukkan pentingnya pariwisata dalam kontribusi terhadap pertumbuhan ekonomi dan pelestarian warisan budaya.
Strategi Pengembangan Eduwisata dan Ekowisata Berbasis Masyarakat
Authors: Yusuf Amier Dhonny
Published: January 2025

Penelitian ini bertujuan untuk mengeksplorasi dan merumuskan strategi pengembangan ekowisata berbasis masyarakat di Desa Lebakmuncang, Ciwidey. Dengan kekayaan alam dan budaya yang melimpah, desa ini memiliki potensi besar untuk pengembangan ekowisata yang berkelanjutan. Metode penelitian yang digunakan adalah kualitatif, melalui wawancara mendalam dengan masyarakat, pengelola wisata, serta observasi lapangan. Hasil penelitian menunjukkan bahwa keterlibatan masyarakat, peningkatan infrastruktur, dan strategi pemasaran yang efektif adalah kunci untuk pengembangan ekowisata yang berhasil. Penelitian ini diharapkan dapat menjadi acuan bagi pengembangan ekowisata di desa-desa lain di Indonesia.
Pengembangan Potensi Desa Wisata Melalui Gerakan Masyarakat Sadar Wisata
Authors: Rusmana Odang , Syadad Saefullah Moch. Agus , Sudayat Ridwan Iskandar
Published: January 2025

Potensi desa dapat digali dan dikembangkan melalui kemampuan Kelompok Penggerak Pariwisata (Kompepar) dan Kelompok Sadar Wisata (Pokdarwis). Keberadaan mereka perlu memiliki pengetahuan, keahlian dan pengalaman supaya dapat menjalankan fungsi dan perannya secara maksimal dengan harapan tujuan pariwisata dapat tercapai. Peningkatan kualitas Kompepar dan Pokdarwis dapat diupayakan melalui penyuluhan dan pelatihan serta pembinaan secara berkelanjutan. Materi Pelayanan Prima dan sadar wisata merupakan aspek yang diperlukan dalam memberikan pelayanan jasa kepada wisatawan. Dengan harapan mereka merasa puas dan berkelanjutan untuk mengunjungi objek wisata. Tujuan dari kegiatan ini adalah memberikan penyuluhan dan pelatihan dengan materi pelayanan prima dan sadar wisata guna meningkatkan kompetensi anggota Kompepar dan Pokdarwis Desa Margacinta. Metode yang digunakan dalam kegiatan ini terdiri dari lima tahapan diantaranya, tahap survey lokasi dan observasi, tahap perizinan, tahap pengembangan materi, tahap kegiatan pembinaan dan tahap evaluasi kegiatan. Dari hasil kegiatan ini didapatkan hasil 100% peserta puas pada seluruh kegiatan ini.
Evaluation of the Impact of Tourism on Environmental Sustainability at the Situ Bagendit Tourist Destination
Authors: Adiatma Dani , Rukma Deden Firman Syuyaman
Published: January 2025

This research evaluates the impact of tourism on environmental sustainability at Situ Bagendit, a natural tourist destination in Garut Regency, West Java. The increase in tourist numbers has led to both positive and negative environmental impacts, such as water pollution, waste accumulation, and ecosystem degradation. The mixed-methods approach used in this study involved field observations, interviews with local stakeholders, and surveys with tourists and residents. The findings indicate significant challenges, including pollution from motorized boats and inadequate waste management, but also highlight increased community awareness and sustainable initiatives. The study recommends improvements in environmental regulations, waste management systems, and educational programs for tourists.
Le Lac Pavin. Historique et hydrobiologie
Authors: Omaly Nicole
Published: January 2025

Situé dans le massif des monts Dore, le lac Pavin, formé il y a environ 6 600 ans, à la suite d’une explosion volcanique, couvre une superficie de 44 ha, sa profondeur atteint 92,10 m. Il a été donné aux habitants de la ville de Besse-en-Chandesse par les comtesses de Bourgogne et d’Auvergne en 1514. Actuellement, il est empoissonné et ses eaux abritent truites, ombles-chevaliers et perches.

Ses eaux sont soumises à deux périodes de circulation, l’une automnale avant que le lac soit pris sous la glace, l’autre printanière à la suite du dégel ; mais il reste au fond du lac une couche morte qui n’est pas renouvelée. Elle est dépourvue d’oxygène et contient de l’H2S impropre à toute vie animale. Cette couche serait actuellement en formation. Elle est probablement due à la décomposition des organismes vivants dans l’eau. La zone supérieure (0-50 m) des eaux du lac est très peu minéralisée par rapport à la zone profonde.

Depuis la fin du siècle dernier, de nombreux auteurs ont étudié la flore et la faune. Une mise au point du travail floristique et faunistique effectué par les auteurs depuis le siècle dernier vient de paraître. D’après la composition physicochimique des eaux et le peuplement animal et végétal, c’est un lac de type méso-oligotrophe. Peu de travaux portent sur la région benthique. Les poissons viennent puiser leur nourriture dans la zone pélagique riche en plancton. Un petit Crustacé Copépode rouge particulièrement abondant donne aux poissons leur chair saumonée. Des travaux d’évaluation de la biomasse de la productivité primaire et secondaire et de l’énergie utilisée mériteraient d'être entrepris dans les années à venir.
Sur la mise en place du granite de Gelles (Puy-de-Dôme)
Authors: Fernandez Angel , Tempier Paul
Published: January 2025

La zone étudiée se situe à l’ouest de Clermont-Ferrand (Puy-de-Dôme) ; elle est comprise entre la vallée de la Sioule et le Sillon Houiller.

L’étude porte essentiellement sur le granite de Gelles, qui apparaît sous forme d’un petit massif allongé ENE-WSW, présentant une apophyse orientée NS dans sa partie nord. Le diamètre maximum du massif est de 13 km et le minimum de 7 km.

Il s’agit d’un granite intrusif, qui s’est mis en place dans une série cristallophyllienne assez complète, allant des micaschistes aux anatexites à cordiérite. L’analyse des structures internes du granite, et ses relations avec les roches encaissantes, ont mis en évidence une mise en place diapirique, avec un mouvement ascensionnel relatif plus marqué dans la partie sud du massif.
Géochronologie sur l'âge d'une des coulées du Puy de Banson (Petite chaîne des Puys, France)
Authors: Pelletier Henri , Tempier Paul
Published: January 2025

Le Puy de Banson, volcan de la petite chaîne des Puys a émis un certain nombre de coulées dont l'une recouvre un paléosol comportant des bois carbonisés. Une datation au carbone 14 indique un âge égal ou supérieur à 35000 ans BP.
Caractérisation et évolution géochimique superficielle d'un massif granitique fossilisé par des formations volcaniques près du Falgoux (Cantal)
Authors: Dejou Jean , Kimpe Christian de , Larroque Pierre , Mayenobe Christiane , Moynac Pierre
Published: January 2025

A small granitic stock was located and sampled in the Mars Valley, near Falgoux, Cantal. This stock that intruded the metamorphic bedrock was covered by the Miocene breccias and basalts which, at that site, have an approximate thickness of 350 m.

This granite has been transformed into a saprolite over several meters. The main features of the saprolite are an alkaline pH and a fully saturated exchange complex. The effect of the volcanic formation overbruden is extremely important. It eroded the upper part of the alteration profile and prevented further evolution of the saprolite, which has a chemical composition very close to that of the fresh granite.
Caractérisation d’un niveau argileux surmontant une arène granitique et fossilisé par les brèches volcaniques près du Falgoux (Cantal)
Authors: Dejou Jean , Kimpe Christian de , Larroque Pierre , Mayenobe Christiane , Moynac Pierre
Published: January 2025

L’arène du massif granitique localisé à proximité du Falgoux (Cantal) est surmontée d’une formation argileuse d'épaisseur variable (8 à 15 cm), visible sur une quinzaine de mètres et recouverte elle-même par les brèches volcaniques miocènes de la vallée du Mars. Elle se subdivise en deux niveaux de teinte et de composition différentes. Le niveau supérieur verdâtre est constitué d’une smectite largement dominante associée à une kaolinite. Celle-ci devient prépondérante dans le niveau inférieur blanchâtre. De plus, elle est associée à un minéral micacé, absent dans le niveau supérieur et à une smectite de nature différente de la précédente. Cet exemple illustre toute l’importance du «site» et de son environnement dans la genèse des minéraux argileux secondaires.