bluuebunny/crossref_metadata_2025 huggingface dataset:
Data Supplement from High-Throughput Time-Resolved FRET Reveals Akt/PKB Activation as a Poor Prognostic Marker in Breast Cancer
Authors: Veeriah Selvaraju , Leboucher Pierre , de Naurois Julien , Jethwa Nirmal , Nye Emma , Bunting Tamara , Stone Richard , Stamp Gordon , Calleja Véronique , Jeffrey Stefanie S. , Parker Peter J. , Larijani Banafshé
Published: March 2023

Supplementary Methods
Supplementary Figure Legends from Transient Ablation of Regulatory T cells Improves Antitumor Immunity in Colitis-Associated Colon Cancer
Authors: Pastille Eva , Bardini Katrin , Fleissner Diana , Adamczyk Alexandra , Frede Annika , Wadwa Munisch , von Smolinski Dorthe , Kasper Stefan , Sparwasser Tim , Gruber Achim D. , Schuler Martin , Sakaguchi Shimon , Roers Axel , Müller Werner , Hansen Wiebke , Buer Jan , Westendorf Astrid M.
Published: March 2023

PDF file - 204K
Supplementary Methods from ERBB3-Independent Activation of the PI3K Pathway in EGFR-Mutant Lung Adenocarcinomas
Authors: Song Xiaoling , Fan Pang-Dian , Bantikassegn Amlak , Guha Udayan , Threadgill David W. , Varmus Harold , Politi Katerina
Published: March 2023

Supplementary Methods. Description of additional methods and procedures used in the study.
Supplementary Figure S7 from ERBB3-Independent Activation of the PI3K Pathway in EGFR-Mutant Lung Adenocarcinomas
Authors: Song Xiaoling , Fan Pang-Dian , Bantikassegn Amlak , Guha Udayan , Threadgill David W. , Varmus Harold , Politi Katerina
Published: March 2023

Supplementary Figure S7. Effect of acute loss of ERBB3 in EGFR mutant lung tumors.
Supplementary Figure S6 from ERBB3-Independent Activation of the PI3K Pathway in EGFR-Mutant Lung Adenocarcinomas
Authors: Song Xiaoling , Fan Pang-Dian , Bantikassegn Amlak , Guha Udayan , Threadgill David W. , Varmus Harold , Politi Katerina
Published: March 2023

Supplementary Figure S6. Efficient knock-down of ERBB2 and ERBB3 in PC9 and H3255 cells.
Supplementary Figure S4 from ERBB3-Independent Activation of the PI3K Pathway in EGFR-Mutant Lung Adenocarcinomas
Authors: Song Xiaoling , Fan Pang-Dian , Bantikassegn Amlak , Guha Udayan , Threadgill David W. , Varmus Harold , Politi Katerina
Published: March 2023

Supplementary Figure S4. p85 associates with mutant EGFR and GAB2 in mutant EGFR-driven mouse lung tumors regardless of the presence of ERBB3.
Supplementary Figure S1 from ERBB3-Independent Activation of the PI3K Pathway in EGFR-Mutant Lung Adenocarcinomas
Authors: Song Xiaoling , Fan Pang-Dian , Bantikassegn Amlak , Guha Udayan , Threadgill David W. , Varmus Harold , Politi Katerina
Published: March 2023

Supplementary Figure S1. ERBB3 interacts with EGFRL858R in vitro.
Supplementary Table 1 from Genetic and Phenotypic Diversity in Breast Tumor Metastases
Authors: Almendro Vanessa , Kim Hee Jung , Cheng Yu-Kang , Gönen Mithat , Itzkovitz Shalev , Argani Pedram , van Oudenaarden Alexander , Sukumar Saraswati , Michor Franziska , Polyak Kornelia
Published: March 2023

XLSX file - 14K, Clinical information of the paired metastasis and primary tumors (PR) and lymph node (LN) metastasis series.
Data Supplement from Intestinal Epithelial HuR Modulates Distinct Pathways of Proliferation and Apoptosis and Attenuates Small Intestinal and Colonic Tumor Development
Authors: Giammanco Antonina , Blanc Valerie , Montenegro Grace , Klos Coen , Xie Yan , Kennedy Susan , Luo Jianyang , Chang Sung-Hee , Hla Timothy , Nalbantoglu ILKe , Dharmarajan Sekhar , Davidson Nicholas O.
Published: March 2023

Supplemental Figure S2. Intestinal HuR deletion does not influence ASBT expression or bile acid homeostasis.
Supplemental Figure 4 from Mitochondrial MKP1 Is a Target for Therapy-Resistant HER2-Positive Breast Cancer Cells
Authors: Candas Demet , Lu Chung-Ling , Fan Ming , Chuang Frank Y.S. , Sweeney Colleen , Borowsky Alexander D. , Li Jian Jian
Published: March 2023

Supplemental Figure 4. Cell viability following MKP1 inhibitior, Sanguinarine, treatment in SKBR3 cells
Supplementary Table S1 from TGFβ Receptor 1: An Immune Susceptibility Gene in HPV-Associated Cancer
Authors: Levovitz Chaya , Chen Dan , Ivansson Emma , Gyllensten Ulf , Finnigan John P. , Alshawish Sara , Zhang Weijia , Schadt Eric E. , Posner Marshal R. , Genden Eric M. , Boffetta Paolo , Sikora Andrew G.
Published: March 2023

Supplementary Table S1. Normalized Average E6 Seroreactivity in HNC Subsites
Supplemental Experimental Procedures from Mitochondrial MKP1 Is a Target for Therapy-Resistant HER2-Positive Breast Cancer Cells
Authors: Candas Demet , Lu Chung-Ling , Fan Ming , Chuang Frank Y.S. , Sweeney Colleen , Borowsky Alexander D. , Li Jian Jian
Published: March 2023

Supplemental Experimental Procedures. The details of plasmid construction and siRNA synthesis
Supplementary Materials and Methods from Failure to Induce Apoptosis via BCL-2 Family Proteins Underlies Lack of Efficacy of Combined MEK and PI3K Inhibitors for KRAS-Mutant Lung Cancers
Authors: Hata Aaron N. , Yeo Alan , Faber Anthony C. , Lifshits Eugene , Chen Zhao , Cheng Katherine A. , Walton Zandra , Sarosiek Kristopher A. , Letai Anthony , Heist Rebecca S. , Mino-Kenudson Mari , Wong Kwok-Kin , Engelman Jeffrey A.
Published: March 2023

PDF file - 94KB
Supplementary Figure 5 from Function-Blocking ERBB3 Antibody Inhibits the Adaptive Response to RAF Inhibitor
Authors: Kugel Curtis H. , Hartsough Edward J. , Davies Michael A. , Setiady Yulius Y. , Aplin Andrew E.
Published: March 2023

PDF file - 139K, MCL1 and combo treatment.
Supplementary Figure 4 from Function-Blocking ERBB3 Antibody Inhibits the Adaptive Response to RAF Inhibitor
Authors: Kugel Curtis H. , Hartsough Edward J. , Davies Michael A. , Setiady Yulius Y. , Aplin Andrew E.
Published: March 2023

PDF file - 242K, A375 in vivo.
Data Supplement from TIGAR Has a Dual Role in Cancer Cell Survival through Regulating Apoptosis and Autophagy
Authors: Xie Jia-Ming , Li Bin , Yu Hong-Pei , Gao Quan-Geng , Li Wei , Wu Hao-Rong , Qin Zheng-Hong
Published: March 2023

Supplemental Figure S4. Knockdown of TIGAR enhanced epirubicin-induced activation of caspase 3 and apoptosis.
Supplementary Figure 1 from Function-Blocking ERBB3 Antibody Inhibits the Adaptive Response to RAF Inhibitor
Authors: Kugel Curtis H. , Hartsough Edward J. , Davies Michael A. , Setiady Yulius Y. , Aplin Andrew E.
Published: March 2023

PDF file - 202K, A375 RPPA.
Supplementary Figure Legends from Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma
Authors: Gopal Y.N. Vashisht , Rizos Helen , Chen Guo , Deng Wanleng , Frederick Dennie T. , Cooper Zachary A. , Scolyer Richard A. , Pupo Gulietta , Komurov Kakajan , Sehgal Vasudha , Zhang Jiexin , Patel Lalit , Pereira Cristiano G. , Broom Bradley M. , Mills Gordon B. , Ram Prahlad , Smith Paul D. , Wargo Jennifer A. , Long Georgina V. , Davies Michael A.
Published: March 2023

Supplementary Figure Legends. This file contains the text legends that describe the data presented in the supplementary figures.
Supplementary Table S2 from RHPN2 Drives Mesenchymal Transformation in Malignant Glioma by Triggering RhoA Activation
Authors: Danussi Carla , Akavia Uri David , Niola Francesco , Jovic Andreja , Lasorella Anna , Pe'er Dana , Iavarone Antonio
Published: March 2023

Table S2. Drivers identified by Multi-Reg
Supplementary Information from Downregulated miR329 and miR410 Promote the Proliferation and Invasion of Oral Squamous Cell Carcinoma by Targeting Wnt-7b
Authors: Shiah Shine-Gwo , Hsiao Jenn-Ren , Chang Wei-Min , Chen Ya-Wen , Jin Ying-Tai , Wong Tung-Yiu , Huang Jehn-Shyun , Tsai Sen-Tien , Hsu Yuan-Ming , Chou Sung-Tau , Yen Yi-Chen , Jiang Shih Sheng , Shieh Yi-Shing , Chang I-Shou , Hsiao Michael , Chang Jang-Yang
Published: March 2023

Supplementary Information. Include supplementary material, methods, table title and figure legends
Data Supplement from IL4 Receptor ILR4α Regulates Metastatic Colonization by Mammary Tumors through Multiple Signaling Pathways
Authors: Venmar Katherine T. , Carter Kathy J. , Hwang Daniel G. , Dozier E. Ashley , Fingleton Barbara
Published: March 2023

Supplemental Figure 6: The IL4/IL4Ra interaction promotes colonization ability in vitro
Data Supplement from Afatinib Enhances the Efficacy of Conventional Chemotherapeutic Agents by Eradicating Cancer Stem–like Cells
Authors: Wang Xiao-kun , He Jie-hua , Xu Jing-hong , Ye Sheng , Wang Fang , Zhang Hui , Huang Zhen-cong , To Kenneth Kin Wah , Fu Li-wu
Published: March 2023

Supplementary Table S1. Acute leukemia patient characteristics.
Data Supplement from Afatinib Enhances the Efficacy of Conventional Chemotherapeutic Agents by Eradicating Cancer Stem–like Cells
Authors: Wang Xiao-kun , He Jie-hua , Xu Jing-hong , Ye Sheng , Wang Fang , Zhang Hui , Huang Zhen-cong , To Kenneth Kin Wah , Fu Li-wu
Published: March 2023

Supplementary Figure S3. Body weight changes in xenograft model in athymic nude mice with time, and a concentration-dependent increase in DNMTs activity under treatment with afatinib.
Data Supplement from Afatinib Enhances the Efficacy of Conventional Chemotherapeutic Agents by Eradicating Cancer Stem–like Cells
Authors: Wang Xiao-kun , He Jie-hua , Xu Jing-hong , Ye Sheng , Wang Fang , Zhang Hui , Huang Zhen-cong , To Kenneth Kin Wah , Fu Li-wu
Published: March 2023

Supplementary Figure S4. A representative Western blot of the effect of afatinib on AKT and ERK 1/2 phosphorylation.
Supplementary Figure S4 from Selective In Vivo Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe
Authors: Stangl Stefan , Varga Julia , Freysoldt Bianca , Trajkovic-Arsic Marija , Siveke Jens T. , Greten Florian R. , Ntziachristos Vasilis , Multhoff Gabriele
Published: March 2023

Supplemental Figures S4A,B,C,D: Primary tumor growth kinteics and size distribution of 4T1 lung metastases of CT26 (s.c.) and 4T1 (o.t.) tumors. Figure S4A: Tumor volume of CT26 (s.c.) tumors in the neck area. Figure S4B: Tumor volume of 4T1 (o.t.) tumors in the mammary gland as determined by sonography. Figure S4C,D: Size distribution of lung metastases of 4T1 tumors on day 25.
Supplementary Figure S3 from Selective In Vivo Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe
Authors: Stangl Stefan , Varga Julia , Freysoldt Bianca , Trajkovic-Arsic Marija , Siveke Jens T. , Greten Florian R. , Ntziachristos Vasilis , Multhoff Gabriele
Published: March 2023

Supplemental Figure S3: Immunohistochemical staining of tumors using cmHsp70.1 monoclonal antibody
Supplementary Figure Legend, Tables 1 - 2 from Manganoporphyrins Increase Ascorbate-Induced Cytotoxicity by Enhancing H2O2 Generation
Authors: Rawal Malvika , Schroeder Samuel R. , Wagner Brett A. , Cushing Cameron M. , Welsh Jessemae L. , Button Anna M. , Du Juan , Sibenaller Zita A. , Buettner Garry R. , Cullen Joseph J.
Published: March 2023

PDF file - 102K, Table 1. AscH- and MnT4MPyP are synergistic as seen by Combination Index (CI) and Dose Reduction Index (DRI). Table 2. Summary statistics for tumor volume measurements in the generalized estimating equations analysis.
Supplementary Figure Legends from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: March 2023

PDF file - 78K
Supplementary Figure 5 from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: March 2023

PDF file - 71K, Luciferase assays the effect of Sp3 and Sp4 on miR-22 transcription regulation.
Supplementary Figure 2 from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: March 2023

PDF file - 37K, Luciferase assays the effect of Sp3 and Sp4 on CD147 transcription regulation.
Supplementary Table 3 from Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
Authors: Richards Kristy L. , Motsinger-Reif Alison A. , Chen Hsiao-Wei , Fedoriw Yuri , Fan Cheng , Nielsen Dahlia M. , Small George W. , Thomas Rachael , Smith Chris , Dave Sandeep S. , Perou Charles M. , Breen Matthew , Borst Luke B. , Suter Steven E.
Published: March 2023

PDF file - 41K, Distribution of lymphoma samples into "Ongoing" or "Static" categories based on the proportion of IGHV subclones that are identical at the CDR3 region for each sample.
Supplementary Figure 3 from Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
Authors: Richards Kristy L. , Motsinger-Reif Alison A. , Chen Hsiao-Wei , Fedoriw Yuri , Fan Cheng , Nielsen Dahlia M. , Small George W. , Thomas Rachael , Smith Chris , Dave Sandeep S. , Perou Charles M. , Breen Matthew , Borst Luke B. , Suter Steven E.
Published: March 2023

PDF file - 881K, Western blot comparing phospho-NF-κB (p65) levels in "ABC-like" and "GCB-like" canine samples.
Supplementary Figure 1 from Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
Authors: Richards Kristy L. , Motsinger-Reif Alison A. , Chen Hsiao-Wei , Fedoriw Yuri , Fan Cheng , Nielsen Dahlia M. , Small George W. , Thomas Rachael , Smith Chris , Dave Sandeep S. , Perou Charles M. , Breen Matthew , Borst Luke B. , Suter Steven E.
Published: March 2023

PDF file - 2708K, Immunohistochemistry of cBCLs.
Supplementary Table S1 from Novel Paracrine Modulation of Notch–DLL4 Signaling by Fibulin-3 Promotes Angiogenesis in High-Grade Gliomas
Authors: Nandhu Mohan S. , Hu Bin , Cole Susan E. , Erdreich-Epstein Anat , Rodriguez-Gil Diego J. , Viapiano Mariano S.
Published: March 2023

Antibodies used for Western blotting and immunohistochemistry.
Supplementary information from Cellular Disposal of miR23b by RAB27-Dependent Exosome Release Is Linked to Acquisition of Metastatic Properties
Authors: Ostenfeld Marie Stampe , Jeppesen Dennis K. , Laurberg Jens R. , Boysen Anders T. , Bramsen Jesper B. , Primdal-Bengtson Bjarke , Hendrix An , Lamy Philippe , Dagnaes-Hansen Frederik , Rasmussen Mads H. , Bui Khan H. , Fristrup Niels , Christensen Erik I. , Nordentoft Iver , Morth Jens P. , Jensen Jørgen B. , Pedersen Jakob S. , Beck Martin , Theodorescu Dan , Borre Michael , Howard Kenneth A. , Dyrskjøt Lars , Ørntoft Torben Falck
Published: March 2023

Supplementary materials&methods and figure legends for supplementary figures and tables.
Supplementary Figure S1 from Sentinel Lymph Node Biopsy Revisited: Ultrasound-Guided Photoacoustic Detection of Micrometastases Using Molecularly Targeted Plasmonic Nanosensors
Authors: Luke Geoffrey P. , Myers Jeffrey N. , Emelianov Stanislav Y. , Sokolov Konstantin V.
Published: March 2023

Identification of the mouse anatomy from US images.
Supplementary Table S2 from PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer
Authors: Yao Ruosi , Jiang Hao , Ma Yuhui , Wang Liping , Wang Lin , Du Juan , Hou Pingfu , Gao Yanyan , Zhao Li , Wang Guannan , Zhang Yu , Liu Dong-Xu , Huang Baiqu , Lu Jun
Published: March 2023

Expression of PRMT7 in clinical breast carcinoma samples
Supplementary Figure S11 from CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression
Authors: Takayama Ken-ichi , Suzuki Takashi , Fujimura Tetsuya , Urano Tomohiko , Takahashi Satoru , Homma Yukio , Inoue Satoshi
Published: March 2023

Supplementary Figure S11. A model for the functions of CtBP2 in modulating AR signaling in prostate cancer.
Supplementary Figure Legends, Tables 1 - 2 from CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression
Authors: Takayama Ken-ichi , Suzuki Takashi , Fujimura Tetsuya , Urano Tomohiko , Takahashi Satoru , Homma Yukio , Inoue Satoshi
Published: March 2023

Supplementary Table S1. Primer sequences. Supplementary Table S2. Association between CtBP2 immunohistochemical status and clinicopathological parameters in 105 human prostate carcinomas.
Supplementary Video #4 from Live-Cell Imaging of Invasion and Intravasation in an Artificial Microvessel Platform
Authors: Wong Andrew D. , Searson Peter C.
Published: March 2023

A single MDA-MB-231 breast cancer cell invading through the ECM towards an HMVEC vessel under shear stress (12-15 dyne cm-2).
Supplemental Table and Figure Legends from Hedgehog Signaling Drives Radioresistance and Stroma-Driven Tumor Repopulation in Head and Neck Squamous Cancers
Authors: Gan Gregory N. , Eagles Justin , Keysar Stephen B. , Wang Guoliang , Glogowska Magdalena J. , Altunbas Cem , Anderson Ryan T. , Le Phuong N. , Morton J. Jason , Frederick Barbara , Raben David , Wang Xiao-Jing , Jimeno Antonio
Published: March 2023

Supplemental Table and Figure Legends. Legends for Supplemental Figures S1-S6 and Supplemental Tables S1-S2.
Supplementary Figures 1 - 2, Methods, Legends from Live-Cell Imaging of Invasion and Intravasation in an Artificial Microvessel Platform
Authors: Wong Andrew D. , Searson Peter C.
Published: March 2023

Supplementary video legends; supplementary Figures S1 and S2; supplementary experimental procedures. Supplementary Figure S1. 3D projection from above and side of a confocal z-stack. Supplementary Figure S2. A, Time lapse images of an intravasating tumor cell.
Supplemental Table S1 from Transient SNAIL1 Expression Is Necessary for Metastatic Competence in Breast Cancer
Authors: Tran Hung D. , Luitel Krishna , Kim Michael , Zhang Kun , Longmore Gregory D. , Tran David D.
Published: March 2023

Supplemental Table S1. Spatiotemporal expression of SNAIL1 in MMTV-PyMT mice
Supplemental Figure S4 from Transient SNAIL1 Expression Is Necessary for Metastatic Competence in Breast Cancer
Authors: Tran Hung D. , Luitel Krishna , Kim Michael , Zhang Kun , Longmore Gregory D. , Tran David D.
Published: March 2023

Supplemental Figure S4. Related to Figure 3: SNAIL1 expression in primary breast tumors precedes detection of DTCs, but SNAIL1 is not expressed by DTCs and lung metastases in MMTV-PyMT mice
Supplementary Figure 2 from Molecular Modulation of Estrogen-Induced Apoptosis by Synthetic Progestins in Hormone Replacement Therapy: An Insight into the Women's Health Initiative Study
Authors: Sweeney Elizabeth E. , Fan Ping , Jordan V. Craig
Published: March 2023

Supplementary Figure 2. MCF-7:5C cells were treated with Dex (A), MPA (B), or NETA (C) at concentrations ranging from 10-10 M to 10-6 M for seven days, and DNA was quantified.
Supplemental Figure S3 from Transient SNAIL1 Expression Is Necessary for Metastatic Competence in Breast Cancer
Authors: Tran Hung D. , Luitel Krishna , Kim Michael , Zhang Kun , Longmore Gregory D. , Tran David D.
Published: March 2023

Supplemental Figure S3. Related to Figure 2F-J: SNAIL1 expression in primary breast tumors correlates with increased invasion
Supporting information_Figure legends from mTORC1-Driven Tumor Cells Are Highly Sensitive to Therapeutic Targeting by Antagonists of Oxidative Stress
Authors: Li Jing , Shin Sejeong , Sun Yang , Yoon Sang-Oh , Li Chenggang , Zhang Erik , Yu Jane , Zhang Jianming , Blenis John
Published: March 2023

This document contains figure legends for the supporting figures
Supplementary Figure Legends from Influence of Drug Formulation on OATP1B-Mediated Transport of Paclitaxel
Authors: Nieuweboer Annemieke J.M. , Hu Shuiying , Gui Chunshan , Hagenbuch Bruno , Ghobadi Moghaddam-Helmantel Inge M. , Gibson Alice A. , de Bruijn Peter , Mathijssen Ron H.J. , Sparreboom Alex
Published: March 2023

PDF file - 61KB
Supplementary Figure 1 from Influence of Drug Formulation on OATP1B-Mediated Transport of Paclitaxel
Authors: Nieuweboer Annemieke J.M. , Hu Shuiying , Gui Chunshan , Hagenbuch Bruno , Ghobadi Moghaddam-Helmantel Inge M. , Gibson Alice A. , de Bruijn Peter , Mathijssen Ron H.J. , Sparreboom Alex
Published: March 2023

PDF file - 636KB, In vitro transport of paclitaxel by OATP1B1 and OATP1B3.
Supplementary Figure 2 from A Hypusine–eIF5A–PEAK1 Switch Regulates the Pathogenesis of Pancreatic Cancer
Authors: Fujimura Ken , Wright Tracy , Strnadel Jan , Kaushal Sharmeela , Metildi Cristina , Lowy Andrew M. , Bouvet Michael , Kelber Jonathan A. , Klemke Richard L.
Published: March 2023

Contains additional data on the growth of PDAC cells with eIF5A knockdown or overexpression.
Supplementary Table S1 from Distinct Subpopulations of Head and Neck Cancer Cells with Different Levels of Intracellular Reactive Oxygen Species Exhibit Diverse Stemness, Proliferation, and Chemosensitivity
Authors: Chang Ching-Wen , Chen Yu-Syuan , Chou Shiu-Huey , Han Chia-Li , Chen Yu-Ju , Yang Cheng-Chieh , Huang Chih-Yang , Lo Jeng-Fan
Published: March 2023

Supplementary Table S1. Antibodies and reagents used.
Supplementary Figure 4 from Targeting of miR34a–NOTCH1 Axis Reduced Breast Cancer Stemness and Chemoresistance
Authors: Park Eun Young , Chang EunSun , Lee Eun Ji , Lee Hyun-Woo , Kang Hyeok-Gu , Chun Kyung-Hee , Woo Yu Mi , Kong Hyun Kyung , Ko Je Yeong , Suzuki Hiromu , Song Erwei , Park Jong Hoon
Published: March 2023

Supplementary Figure 4. Overexpression of miR-34a by lentiviral system in primary cells.
Supplementary Figure 1 from Targeting of miR34a–NOTCH1 Axis Reduced Breast Cancer Stemness and Chemoresistance
Authors: Park Eun Young , Chang EunSun , Lee Eun Ji , Lee Hyun-Woo , Kang Hyeok-Gu , Chun Kyung-Hee , Woo Yu Mi , Kong Hyun Kyung , Ko Je Yeong , Suzuki Hiromu , Song Erwei , Park Jong Hoon
Published: March 2023

Supplementary Figure 1. Expression levels of cancer stem cell markers in tumorsphere cells.
Supplemental Figure S2 from Targeting Cancer Stem–like Cells as an Approach to Defeating Cellular Heterogeneity in Ewing Sarcoma
Authors: Cornaz-Buros Sandrine , Riggi Nicolo , DeVito Claudio , Sarre Alexandre , Letovanec Igor , Provero Paolo , Stamenkovic Ivan
Published: March 2023

Supplemental Figure S2. ESFT-1 response to enoxacin in vivo.
Data Supplement from Validation and Structural Characterization of the LEDGF/p75–MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia
Authors: Čermáková Kateřina , Tesina Petr , Demeulemeester Jonas , El Ashkar Sara , Méreau Hélène , Schwaller Juerg , Řezáčová Pavlína , Veverka Vaclav , De Rijck Jan
Published: March 2023

Supplementary Tables S1-S6. Primers used in this study (S1); The statistics for the final water-refined set of NMR structures of IBD-MLL 140-160 complex (S2); The solvent-accessible surface area (BSA) of individual lBD residues buried upon IBD-HIV1-integrase (HIV IN) or IBD-MLL complex formation is expressed as a portion of the residue total solvent accessible area (BSA in %). The BSA was calculated using PDBePISA tool (S3); Effect of LEDGF/p75 mutations on the interaction with MLL as measured by AlphaScreen (S4); Effect of LEDGF/p75 mutations defective for binding to HIV-1 integrase on the interaction with MLL as measured by AlphaScreen (S5); Melting temperatures of the PWWP and IBD domain of wild type LEDGF/p75 or its mutants as determined by DSF (S6).
Data Supplement from Natural Killer Cells Eradicate Galectin-1–Deficient Glioma in the Absence of Adaptive Immunity
Authors: Baker Gregory J. , Chockley Peter , Yadav Viveka Nand , Doherty Robert , Ritt Michael , Sivaramakrishnan Sivaraj , Castro Maria G. , Lowenstein Pedro R.
Published: March 2023

Supplementary Figure S4. GL26-Cit-gal1i cells do not undergo spontaneous cell-death in-vitro.
Data Supplement from Neuronal Pentraxin 2 Supports Clear Cell Renal Cell Carcinoma by Activating the AMPA-Selective Glutamate Receptor-4
Authors: von Roemeling Christina A. , Radisky Derek C. , Marlow Laura A. , Cooper Simon J. , Grebe Stefan K. , Anastasiadis Panagiotis Z. , Tun Han W. , Copland John A.
Published: March 2023

Supplementary Figure Legends
Supporting Data from Oncogenic KRAS Confers Chemoresistance by Upregulating NRF2
Authors: Tao Shasha , Wang Shue , Moghaddam Seyed Javad , Ooi Aikseng , Chapman Eli , Wong Pak K. , Zhang Donna D.
Published: March 2023

Supporting Data. Supporting reference, Supporting Figure Legends and Supporting Materials and Methods
Supplemental Figure 1. In vitro phantom containing 100 μCi 177Lu. from In Vivo Localization of 90Y and 177Lu Radioimmunoconjugates Using Cerenkov Luminescence Imaging in a Disseminated Murine Leukemia Model
Authors: Balkin Ethan R. , Kenoyer Aimee , Orozco Johnnie J. , Hernandez Alexandra , Shadman Mazyar , Fisher Darrell R. , Green Damian J. , Hylarides Mark D. , Press Oliver W. , Wilbur D. Scott , Pagel John M.
Published: March 2023

Supplemental Figure 1. In vitro phantom containing 100 μCi 177Lu. Phantom images were obtained by placing a minimal volume of activity source within a 1.5 mL polypropylene tube, which was then suspended in water inside a larger polypropylene tube. This allowed simulation of Cerenkov radiation through an aquatic medium in order to more closely mimic an activity source within tissue.
Supplemental Figure Legends from AEG-1 Promoter–Mediated Imaging of Prostate Cancer
Authors: Bhatnagar Akrita , Wang Yuchuan , Mease Ronnie C. , Gabrielson Matthew , Sysa Polina , Minn Il , Green Gilbert , Simmons Brian , Gabrielson Kathleen , Sarkar Siddik , Fisher Paul B. , Pomper Martin G.
Published: March 2023

Legend for Supplemental Figures S1-S8.
Supplementary Figures S1-S4 from Paclitaxel Therapy Promotes Breast Cancer Metastasis in a TLR4-Dependent Manner
Authors: Volk-Draper Lisa , Hall Kelly , Griggs Caitlin , Rajput Sandeep , Kohio Pascaline , DeNardo David , Ran Sophia
Published: March 2023

The effects of nab-PXL on upregulation of cytokines in MDA-MB-231 cells expressing dominant negative (DN)-TLR4 or DN-MyD88 and control cell lines (S1); The comparison of nab-PXL and docetaxel effects on the TLR4-positive human and mouse BC cells (S2); FACS analysis of spleen and bone marrow cells (S3); Effect of a blocking mouse CD11b antibody on PXL-induced tumor recruitment of myeloid cells and blood vascular densities (S4).
Data Supplement from TRIB1 Supports Prostate Tumorigenesis and Tumor-Propagating Cell Survival by Regulation of Endoplasmic Reticulum Chaperone Expression
Authors: Mashima Tetsuo , Soma-Nagae Taeko , Migita Toshiro , Kinoshita Ryoko , Iwamoto Atsushi , Yuasa Takeshi , Yonese Junji , Ishikawa Yuichi , Seimiya Hiroyuki
Published: March 2023

Supplementary Table 3 shows TRIB1 protein expression in clinical prostate cancer tissues.
Data Supplement from TRIB1 Supports Prostate Tumorigenesis and Tumor-Propagating Cell Survival by Regulation of Endoplasmic Reticulum Chaperone Expression
Authors: Mashima Tetsuo , Soma-Nagae Taeko , Migita Toshiro , Kinoshita Ryoko , Iwamoto Atsushi , Yuasa Takeshi , Yonese Junji , Ishikawa Yuichi , Seimiya Hiroyuki
Published: March 2023

Supplementary Table 4 shows the expression of TRIB1 and the ER chaperone in prostate cancer specimens.
Data Supplement from EFA6B Antagonizes Breast Cancer
Authors: Zangari Joséphine , Partisani Mariagrazia , Bertucci François , Milanini Julie , Bidaut Ghislain , Berruyer-Pouyet Carole , Finetti Pascal , Long Elodie , Brau Frédéric , Cabaud Olivier , Chetaille Bruno , Birnbaum Daniel , Lopez Marc , Hofman Paul , Franco Michel , Luton Frédéric
Published: March 2023

Supplementary Figures. Fig.S1: Additional confocal images showing that expression of EFA6Bvsvg in MCF7 cells restores normal apico-basal polarity and promotes lumen formation Fig.S2: Analysis of the specificity of EFA6B repression using siRNAs Fig.S3: Additional confocal images showing that repression of EFA6B in MCF7 cells abrogates the assembly of TJ and leads to unorganized aggregates Fig.S4: Exogenous expression of EFA6Bvsvg abrogates the TGFβ-induced EMT in MDCK cells Fig.S5: Analysis of EFA6B/PSD4 mutations and copy number alterations from the cBioPortal website
Data Supplement from EFA6B Antagonizes Breast Cancer
Authors: Zangari Joséphine , Partisani Mariagrazia , Bertucci François , Milanini Julie , Bidaut Ghislain , Berruyer-Pouyet Carole , Finetti Pascal , Long Elodie , Brau Frédéric , Cabaud Olivier , Chetaille Bruno , Birnbaum Daniel , Lopez Marc , Hofman Paul , Franco Michel , Luton Frédéric
Published: March 2023

Supplementary Methods
Supplemental Figure S1 from Aurora-A Inhibition Offers a Novel Therapy Effective against Intracranial Glioblastoma
Authors: Van Brocklyn James R. , Wojton Jeffrey , Meisen Walter H. , Kellough David A. , Ecsedy Jeffery A. , Kaur Balveen , Lehman Norman L.
Published: March 2023

Aurora-A inhibitor effects on proliferation and metabolic activity in GB neurosphere cells, and apoptosis in normal primary astrocytes.
Data Supplement from EFA6B Antagonizes Breast Cancer
Authors: Zangari Joséphine , Partisani Mariagrazia , Bertucci François , Milanini Julie , Bidaut Ghislain , Berruyer-Pouyet Carole , Finetti Pascal , Long Elodie , Brau Frédéric , Cabaud Olivier , Chetaille Bruno , Birnbaum Daniel , Lopez Marc , Hofman Paul , Franco Michel , Luton Frédéric
Published: March 2023

Supplementary Table. Description of the datasets used for EFA6B/PSD4 mRNA expression analysis in breast cancer samples
SuppFigure2 from Changes in Pyruvate Metabolism Detected by Magnetic Resonance Imaging Are Linked to DNA Damage and Serve as a Sensor of Temozolomide Response in Glioblastoma Cells
Authors: Park Ilwoo , Mukherjee Joydeep , Ito Motokazu , Chaumeil Myriam M. , Jalbert Llewellyn E. , Gaensler Karin , Ronen Sabrina M. , Nelson Sarah J. , Pieper Russell O.
Published: March 2023

SuppFigure2. Representative hyperpolarized 13C MRSI data shows T1 post-Gd images, 13C spectra, and Lac/Pyr overlay map of G55 tumor-bearing animals at D0, D1 and D2 following vehicle, BG, TMZ (100 mg/kg), or BG+TMZ treatment. Lac/Pyr dropped in the MGMT-deficient, TMZ-treated group (G55+BG+TMZ) beginning at D1 while all the other groups exhibited increased conversion of pyruvate to lactate. Yellow boxes, tumor.
Supplemental Figure and Table Legends from Androgen Receptor Is the Key Transcriptional Mediator of the Tumor Suppressor SPOP in Prostate Cancer
Authors: Geng Chuandong , Rajapakshe Kimal , Shah Shrijal S. , Shou John , Eedunuri Vijay Kumar , Foley Christopher , Fiskus Warren , Rajendran Mahitha , Chew Sue Anne , Zimmermann Martin , Bond Richard , He Bin , Coarfa Cristian , Mitsiades Nicholas
Published: March 2023

Legends for Supplemental Figures S1-S12 and Supplemental Table S1.
Figure S4 from PELP1 Overexpression in the Mouse Mammary Gland Results in the Development of Hyperplasia and Carcinoma
Authors: Cortez Valerie , Samayoa Cathy , Zamora Andrea , Martinez Lizatte , Tekmal Rajeshwar R. , Vadlamudi Ratna K.
Published: March 2023

Figure S4. Representative IHC images showing the status of diK9me2Characterization of PELP1 Tg mice
Figure S3 from PELP1 Overexpression in the Mouse Mammary Gland Results in the Development of Hyperplasia and Carcinoma
Authors: Cortez Valerie , Samayoa Cathy , Zamora Andrea , Martinez Lizatte , Tekmal Rajeshwar R. , Vadlamudi Ratna K.
Published: March 2023

Figure S3. Representative IHC images showing the status of phos-MAPK
Supplementary Table S1 from Transcriptional Dynamics in Colorectal Carcinogenesis: New Insights into the Role of c-Myc and miR17 in Benign to Cancer Transformation
Authors: Ben-David Eyal , Bester Assaf C. , Shifman Sagiv , Kerem Batsheva
Published: March 2023

WGCNA modules.
Supplementary Tables S1-S8 from Dsh Homolog DVL3 Mediates Resistance to IGFIR Inhibition by Regulating IGF-RAS Signaling
Authors: Gao Shan , Bajrami Ilirjana , Verrill Clare , Kigozi Asha , Ouaret Djamila , Aleksic Tamara , Asher Ruth , Han Cheng , Allen Paul , Bailey Deborah , Feller Stephan , Kashima Takeshi , Athanasou Nicholas , Blay Jean-Yves , Schmitz Sandra , Machiels Jean-Pascal , Upile Nav , Jones Terry M. , Thalmann George , Ashraf Shazad Q. , Wilding Jennifer L. , Bodmer Walter F. , Middleton Mark R. , Ashworth Alan , Lord Christopher J. , Macaulay Valentine M.
Published: March 2023

Supplementary Tables S1-S8. S1: Antibodies used for western blotting, immunoprecipitation and immunofluorescence S2: siRNA libraries and individual siRNAs used in this study S3: Sequences of qPCR primers S4: Z' values in primary siRNA screens S5: Candidate resistance mediators tested in second round screens S6: Validation of screen hits S7: DVL3 expression and clinical parameters in breast and prostate cancer S8:DVL3 IPS on tumor tissue from 22 patients recruited to trials of IGF-1R antibodies
Supplemental Figures 1 - 4 from MHC-Restricted Phosphopeptides from Insulin Receptor Substrate-2 and CDC25b Offer Broad-Based Immunotherapeutic Agents for Cancer
Authors: Zarling Angela L. , Obeng Rebecca C. , Desch A. Nicole , Pinczewski Joel , Cummings Kara L. , Deacon Donna H. , Conaway Mark , Slingluff Craig L. , Engelhard Victor H.
Published: March 2023

Supplemental Figure 1. Sequence of pIRS-21097-1105 TCR chains. Supplemental Figure 2. Sequence of pCDC25b38-46 TCR chains. Supplemental Figure 3. Electroporation of IVT RNA encoding murine TCR chains results in functional cell surface expression of phosphopeptide-specific TCR. Supplemental Figure 4. pSer1100-IRS-2 staining of colon melanoma metastasis
Data Supplement from Trim32 Facilitates Degradation of MYCN on Spindle Poles and Induces Asymmetric Cell Division in Human Neuroblastoma Cells
Authors: Izumi Hideki , Kaneko Yasuhiko
Published: March 2023

Supplementary Figure S10. Trim32 ubiquitinylates MYCN in vitro. Trim32 in TGW cells with or without nocodazole treatment (30ng/ml for 16h) was immunoprecipitated by an anti-Trim32 antibody, and mixed with recombinant GST-MYCN. Then, an in vitro ubiquitinylation assay was performed. Ubiquitinylation ability of Trim32 was active both in interphase and mitosis. Since the ubiquitin ligase activity of Trim32 was inhibited by phosphorylation of PKA in interphase as reported recently (2), Trim32 may be more active in mitosis rather than in interphase. 2. Ichimura T, Taoka M, Shoji I, Kato H, Sato T, Hatakeyama S, et al. 14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation. Journal of cell science. 2013;126:2014-26.
Supplementary Table 3 from Cancer-Associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling
Authors: Lapeire Lore , Hendrix An , Lambein Kathleen , Van Bockstal Mieke , Braems Geert , Van Den Broecke Rudy , Limame Ridha , Mestdagh Pieter , Vandesompele Jo , Vanhove Christian , Maynard Dawn , Lehuédé Camille , Muller Catherine , Valet Philippe , Gespach Christian P. , Bracke Marc , Cocquyt Veronique , Denys Hannelore , De Wever Olivier
Published: March 2023

IDCA: invasive ductal carcinoma, Max diam: maximal diameter, ER: estrogen receptor, PR: progesterone receptor, Pos LN: positive lymph nodes, LVI: lymphovascular invasion, BMI: body mass index.
Data Supplement from Trim32 Facilitates Degradation of MYCN on Spindle Poles and Induces Asymmetric Cell Division in Human Neuroblastoma Cells
Authors: Izumi Hideki , Kaneko Yasuhiko
Published: March 2023

Supplementary Figure S13. Relapse-free survival curves for 20 patients with high Trim32 expression in neuroblastoma and 68 patients with low Trim32 expression. Data was obtained from Public microarray database (R2); http://hgserver1.amc.nl/cgi-bin/r2/main.cgi
Supplementary Figure 3 from Cancer-Associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling
Authors: Lapeire Lore , Hendrix An , Lambein Kathleen , Van Bockstal Mieke , Braems Geert , Van Den Broecke Rudy , Limame Ridha , Mestdagh Pieter , Vandesompele Jo , Vanhove Christian , Maynard Dawn , Lehuédé Camille , Muller Catherine , Valet Philippe , Gespach Christian P. , Bracke Marc , Cocquyt Veronique , Denys Hannelore , De Wever Olivier
Published: March 2023

Upper left panel: Image representing a protein array of 507 proteins used for detection of soluble factors present in a mixture of CMCAAT from two patients. Each protein is spotted in duplicate. The boxes show the positive controls. The brackets indicate adiponectin (1) confirming the adipose nature of CMCAAT, GCSF (2), IL-6 (3), IL-8 (4), leptin (5), LIF (6), OSM (7). Upper right panels: western blot analysis of Y705 pSTAT3 of MCF-7 cells treated for 48h with control medium; neutralizing antibodies against hIL-6, hLIF and hIL-8 (1 µg/ml); rhIL-6, rhLIF and rhIL-8 (10 ng/ml); combination of the recombinant protein with the neutralizing antibody (same concentrations); western blot analysis of MCF-7 cells treated for 48h with CMCAAT and neutralizing antibodies against hIL-6, hLIF and hIL-8 at indicated concentrations. Lower panel: Phase-contrast images of MCF-7 cells treated or 48h with control medium, rhIL-6, rhLIF and rhIL-8 at indicated concentrations, CMCAAT and CMCAAT combined with neutralizing antibodies against hIL-6, hLIF and hIL-8 at indicated concentrations (Scale bar is 100 µm).
Data Supplement from Trim32 Facilitates Degradation of MYCN on Spindle Poles and Induces Asymmetric Cell Division in Human Neuroblastoma Cells
Authors: Izumi Hideki , Kaneko Yasuhiko
Published: March 2023

Supplementary Figure S8. Colocalization of T58-phosphorylated-MYCN and Trim32 to spindle poles in TGW (A) and SK-N-DZ (B) cells under MG132 treatment for 5h. Trim32 is red, MYCN-T58-P or MYCN is green, and DAPI (DNA) is blue. Arrows show spindle poles. Scale bars indicate 10 μm.
Supplementary Figure 1 from Cancer-Associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling
Authors: Lapeire Lore , Hendrix An , Lambein Kathleen , Van Bockstal Mieke , Braems Geert , Van Den Broecke Rudy , Limame Ridha , Mestdagh Pieter , Vandesompele Jo , Vanhove Christian , Maynard Dawn , Lehuédé Camille , Muller Catherine , Valet Philippe , Gespach Christian P. , Bracke Marc , Cocquyt Veronique , Denys Hannelore , De Wever Olivier
Published: March 2023

Flow chart indicating CMCAAT prepared from 25 breast cancer patients and tested in the experimental conditions described throughout the article. OSM concentration was measured by ELISA for the samples indicated in bold type (see also figure 3C).
Data Supplement from Trim32 Facilitates Degradation of MYCN on Spindle Poles and Induces Asymmetric Cell Division in Human Neuroblastoma Cells
Authors: Izumi Hideki , Kaneko Yasuhiko
Published: March 2023

Supplementary Figure S9. TP58 phosphorylation in MYCN is dispensable for interaction with Trim32 in vivo. Each 1mg of lysates from SH-SY5Y cells transfected with the MYCN or MYCN-T58A expression vector was immunoprecipitated with an anti-MYCN antibody. As a control, immunoprecipitates with preimmune mouse immunoglobulin-G (IgG) were used. The immunoprecipitates were then subjected to immunoblotting using an anti-Trim32 antibody. Right panel shows 5% input.
Data Supplement from IL-1β-Mediated Repression of microRNA-101 Is Crucial for Inflammation-Promoted Lung Tumorigenesis
Authors: Wang Lin , Zhang Ling-Fei , Wu Jing , Xu Shu-Jun , Xu Yang-Yang , Li Dangsheng , Lou Jia-Tao , Liu Mo-Fang
Published: March 2023

Supplementary Figure S1. No significant difference in the serum levels of IL-4, IL-6, TNF-a and TGF-B between NSCLC patients and healthy controls. Supplementary Figure S2. Repression of mir-101 is involved in the tumorigenic activity of IL-1B in NSCLC cells. Supplementary Figure S3. IL-1B down-regulates mir-101 via the COX-2/HIF-1alpha pathway in NSCLC cells. Supplementary Figure S4. miR-101 up-regulates let-7 family miRNAs by targeting Lin28B in NSCLC cells. Supplementary Figure S5. Comparison of the expression of Lin28B and miR-101 in A549 and H1299 cells. Supplementary Figure S6. miR-101 plays a tumor suppressive role in NSCLC cells. Supplementary Figure S7. Repression of miR-101 is critical to IL-1B-mediated induction of Cox-2 and Lin28B in NSCLC cells. Supplementary Table S1 Sequences of chemically synthesized DNA and RNA oligonucleotides.
Supplementary Figures S1-S10 from The Notch Pathway Inhibits TGFβ Signaling in Breast Cancer through HEYL-Mediated Crosstalk
Authors: Han Liangfeng , Diehl Adam , Nguyen Nguyen K. , Korangath Preethi , Teo Weiwen , Cho Soonweng , Kominsky Scott , Huso David L. , Feigenbaum Lionel , Rein Alan , Argani Pedram , Landberg Goran , Gessler Manfred , Sukumar Saraswati
Published: March 2023

Supplementary Figures S1-S10. Tests for specificity of the anti-HEYL antibody (S1); Notch pathway induces HEYL expression (S2); In vitro analysis of direct interaction of HEYL and Smad3 in Cos 1 cells (S3); Transcriptional control of TGF-ÃŸ responsive reporter consisting of tandem synthetic Smad-binding elements by luciferase assays (S4); Hematoxylin and eosin (H&E) staining of mammary glands of wild-type or transgenic HEYL+ virgin mice, 13 weeks of age (S5); Mammary gland H&E staining of wild-type or transgenic mice at day 10 of pregnancy (S6); Mammary gland hyperplasia was commonly observed in HEYL+ transgenic mice, Representative photomicrographs from mouse numbers, 1-4 are shown (S7); Expression of HeyL in mammary tumors from two HEYL+ transgenic mice measured by RT-PCR and IHC staining (S8); Expression of downstream effectors of TGFÃŸ, PAI-1 and P15 in HEYL+ transgenic mammary tumors in comparison to normal mammary glands of WT mice (S9); The antagonistic network between Notch and TGF-ÃŸ signaling through the interactions between HEY genes and Smads (S10).
Supplementary Figure 1 from Patient-Derived Ovarian Tumor Xenografts Recapitulate Human Clinicopathology and Genetic Alterations
Authors: Ricci Francesca , Bizzaro Francesca , Cesca Marta , Guffanti Federica , Ganzinelli Monica , Decio Alessandra , Ghilardi Carmen , Perego Patrizia , Fruscio Robert , Buda Alessandro , Milani Rodolfo , Ostano Paola , Chiorino Giovanna , Bani Maria Rosa , Damia Giovanna , Giavazzi Raffaella
Published: March 2023

Supplementary Figure 1. Histologic characteristics of the original patient tumors and corresponding EOC-xenografts.
Supplementary Fig. 5 from Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis
Authors: Menard Julien A. , Christianson Helena C. , Kucharzewska Paulina , Bourseau-Guilmain Erika , Svensson Katrin J. , Lindqvist Eva , Chandran Vineesh Indira , Kjellén Lena , Welinder Charlotte , Bengzon Johan , Johansson Maria C. , Belting Mattias
Published: March 2023

Figure S5. A-D, Hypoxic induction of lipoprotein receptor expression in GBM cells. E, Heparin treatment reverses hypoxic induction of lipoprotein uptake.
Data Supplement from The SIRT1/HIF2α Axis Drives Reductive Glutamine Metabolism under Chronic Acidosis and Alters Tumor Response to Therapy
Authors: Corbet Cyril , Draoui Nihed , Polet Florence , Pinto Adan , Drozak Xavier , Riant Olivier , Feron Olivier
Published: March 2023

Supplementary Figure S4. HIF acetylation is regulated by acidosis-triggered SIRT1 activity.
Supplementary Fig. 1 from Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis
Authors: Menard Julien A. , Christianson Helena C. , Kucharzewska Paulina , Bourseau-Guilmain Erika , Svensson Katrin J. , Lindqvist Eva , Chandran Vineesh Indira , Kjellén Lena , Welinder Charlotte , Bengzon Johan , Johansson Maria C. , Belting Mattias
Published: March 2023

Figure S1. Hypoxic induction of the expression of lipid metabolism related proteins and LDs is not related to acidosis, LDL aggregation or cell toxicity.
Data Supplement from The SIRT1/HIF2α Axis Drives Reductive Glutamine Metabolism under Chronic Acidosis and Alters Tumor Response to Therapy
Authors: Corbet Cyril , Draoui Nihed , Polet Florence , Pinto Adan , Drozak Xavier , Riant Olivier , Feron Olivier
Published: March 2023

Supplementary Figure S6. Model of metabolic adaptation of tumor cells under chronic low pH conditions.
Supplementary Materials, Figures 1 - 3, Tables 1 - 4, 6 - 8 from The 19q12 Bladder Cancer GWAS Signal: Association with Cyclin E Function and Aggressive Disease
Authors: Fu Yi-Ping , Kohaar Indu , Moore Lee E. , Lenz Petra , Figueroa Jonine D. , Tang Wei , Porter-Gill Patricia , Chatterjee Nilanjan , Scott-Johnson Alexandra , Garcia-Closas Montserrat , Muchmore Brian , Baris Dalsu , Paquin Ashley , Ylaya Kris , Schwenn Molly , Apolo Andrea B. , Karagas Margaret R. , Tarway McAnthony , Johnson Alison , Mumy Adam , Schned Alan , Guedez Liliana , Jones Michael A. , Kida Masatoshi , Hosain GM Monawar , Malats Nuria , Kogevinas Manolis , Tardon Adonina , Serra Consol , Carrato Alfredo , Garcia-Closas Reina , Lloreta Josep , Wu Xifeng , Purdue Mark , Andriole Gerald L. , Grubb Robert L. , Black Amanda , Landi Maria T. , Caporaso Neil E. , Vineis Paolo , Siddiq Afshan , Bueno-de-Mesquita H. Bas , Trichopoulos Dimitrios , Ljungberg Börje , Severi Gianluca , Weiderpass Elisabete , Krogh Vittorio , Dorronsoro Miren , Travis Ruth C. , Tjønneland Anne , Brennan Paul , Chang-Claude Jenny , Riboli Elio , Prescott Jennifer , Chen Constance , De Vivo Immaculata , Govannucci Edward , Hunter David , Kraft Peter , Lindstrom Sara , Gapstur Susan M. , Jacobs Eric J. , Diver W. Ryan , Albanes Demetrius , Weinstein Stephanie J. , Virtamo Jarmo , Kooperberg Charles , Hohensee Chancellor , Rodabough Rebecca J. , Cortessis Victoria K. , Conti David V. , Gago-Dominguez Manuela , Stern Mariana C. , Pike Malcolm C. , Van Den Berg David , Yuan Jian-Min , Haiman Christopher A. , Cussenot Olivier , Cancel-Tassin Geraldine , Roupret Morgan , Comperat Eva , Porru Stefano , Carta Angela , Pavanello Sofia , Arici Cecilia , Mastrangelo Giuseppe , Grossman H. Barton , Wang Zhaoming , Deng Xiang , Chung Charles C. , Hutchinson Amy , Burdette Laurie , Wheeler William , Fraumeni Joseph , Chanock Stephen J. , Hewitt Stephen M. , Silverman Debra T. , Rothman Nathaniel , Prokunina-Olsson Ludmila
Published: March 2023

Supplementary Figure 1: Electrophoretic mobility shift assays (EMSA) for CCNE1 SNPs rs8102137 and rs7257330. Supplementary Figure 2: Alignment of cyclin E protein isoforms - WT1, WT2 and ES and ET. Supplementary Figure 3: Functional analysis of cyclin E isoforms.Supplementary Table 1: Description of sub-studies included in NCI-GWAS1 and GWAS2 of bladder cancer. Supplementary Table 2: Characteristics of bladder tissue samples used for mRNA expression analysis. Supplementary Table 3: PCR primers, genotyping and gene expression assays, EMSA probes and antibodies. Supplementary Table 4: Bladder cancer stage and grade information for patients in the combined GWAS1+2 set. Supplementary Table 6: Association with bladder cancer risk with mutual adjustment for CCNE1 variants. Supplementary Table 7: Association with bladder cancer risk for CCNE1 variants previously associated with other cancers and for two non-synonymous coding variants. Supplementary Table 8: Association between cyclin E protein expression (IHC scores), bladder cancer patient characteristics and CCNE1 variants.
Supplementary Table from β-Catenin Contributes to Lung Tumor Development Induced by EGFR Mutations
Authors: Nakayama Sohei , Sng Natasha , Carretero Julian , Welner Robert , Hayashi Yuichiro , Yamamoto Mihoko , Tan Alistair J. , Yamaguchi Norihiro , Yasuda Hiroyuki , Li Danan , Soejima Kenzo , Soo Ross A. , Costa Daniel B. , Wong Kwok-Kin , Kobayashi Susumu S.
Published: March 2023

Clinical information of IHC samples.
Supplementary Figure S6 from β-Catenin Contributes to Lung Tumor Development Induced by EGFR Mutations
Authors: Nakayama Sohei , Sng Natasha , Carretero Julian , Welner Robert , Hayashi Yuichiro , Yamamoto Mihoko , Tan Alistair J. , Yamaguchi Norihiro , Yasuda Hiroyuki , Li Danan , Soejima Kenzo , Soo Ross A. , Costa Daniel B. , Wong Kwok-Kin , Kobayashi Susumu S.
Published: March 2023

Generation of conditional, lung-specific Ctnnb1 knockout/EGFR-L858R-T790M (EGFRTL) transgenic mice.
Supplementary Figure S5 from β-Catenin Contributes to Lung Tumor Development Induced by EGFR Mutations
Authors: Nakayama Sohei , Sng Natasha , Carretero Julian , Welner Robert , Hayashi Yuichiro , Yamamoto Mihoko , Tan Alistair J. , Yamaguchi Norihiro , Yasuda Hiroyuki , Li Danan , Soejima Kenzo , Soo Ross A. , Costa Daniel B. , Wong Kwok-Kin , Kobayashi Susumu S.
Published: March 2023

Effect of ICG-001 in EGFR-LR-TM transgenic mice.