bluuebunny/crossref_metadata_2025 huggingface dataset:
Association Between Skin Reaction and Clinical Benefit in Patients Treated with Anti-Programmed Cell Death 1 Monotherapy for Advanced Non-Small Cell Lung Cancer
Authors: Aso Mari , Toi Yukihiro , Sugisaka Jun , Aiba Tomoiki , Kawana Sachiko , Saito Ryohei , Ogasawara Takahiro , Tsurumi Kyoji , Ono Kana , Shimizu Hisashi , Domeki Yutaka , Terayama Keisuke , Kawashima Yosuke , Nakamura Atsushi , Yamanda Shinsuke , Kimura Yuichiro , Honda Yoshihiro , Sugawara Shunichi
Published: November 2019

Background

Anti-programmed cell death 1 antibody is a standard therapy for advanced non-small cell lung cancer (NSCLC). However, immune-related adverse events (irAEs), such as skin reactions, are frequently observed. Although skin reactions are associated with clinical efficacy in melanoma, this association in advanced NSCLC and predictors of irAEs remain unclear. Accordingly, this study identified potential correlations of skin reactions with clinical efficacy and clinical predictors of development of skin reactions.

Subjects, Materials, and Methods

We retrospectively surveyed patients with advanced NSCLC who received nivolumab or pembrolizumab monotherapy at Sendai Kousei Hospital (n = 155) during January 2016 to April 2018. Treatment efficacy was evaluated in patients with and without skin reactions, and associated predictive markers were determined. A 6-week landmark analysis was conducted to assess the clinical benefit of early skin reactions.

Results

Skin reactions were observed in 51 patients with a median time to onset of 6.4 weeks. The overall response rate (ORR) was significantly higher in patients with skin reactions (57% vs. 19%, p < .001). Median progression-free survival (PFS) durations of 12.9 and 3.5 months and overall survival durations of not reached and 11.4 months were observed in patients with and without skin reactions, respectively. In the 6-week landmark analysis, the ORR was significantly higher in patients with skin reactions, and skin reactions were significantly associated with increased PFS. A multivariate analysis identified pre-existing rheumatoid factor (RF) as an independent predictor of skin reactions.

Conclusion

Skin reactions appeared beneficial in patients treated with nivolumab/pembrolizumab for advanced NSCLC and could be predicted by pre-existing RF. Further large-scale validations studies are warranted.
Pesquisa em educaçao comparada sob condições de interconectividade global
Authors: Schiedeck Soares de Souza Claudia , Streck Danilo Romeu
Published: November 2019

Essa resenha se destina a apresentar o livro “Pesquisa em Educação Comparada sob condições de Interconectividade Global”, de Jürgen Schriewer, a primeira publicação do autor no Brasil. Ao longo de oito capítulos, o pesquisador alemão nos guia por uma abordagem histórica e sociológica da pesquisa comparativa, apresentando conceitos e aprofundando reflexões sobre o tema. Para o autor, esse campo de estudos deve ser considerado a partir dos diferentes domínios estabelecidos para as análises comparativas e internacionais em educação, bem como das dúvidas que se imbricam na temática ao longo do seu desenvolvimento.
Marcas [brancas] do escravismo nas políticas públicas de educação no Brasil contemporâneo
Authors: Ecker Daniel Dall'Igna
Published: November 2019

Este ensaio discorre acerca da construção do direito a educação no Brasil, evidenciando como a presença de pessoas [com pele branca] foram historicamente determinantes na elaboração das políticas de educação do Brasil contemporâneo. Para isso, analisa as Constituições Federais brasileiras (1824; 1891; 1934; 1937; 1946; 1967; 1988), em articulação com estudos sobre as especificidades sócio históricas do país. Através dos materiais, explicita a presença da cor/raça [branca] na formulação das políticas de educação e aponta alguns dos possíveis efeitos dessa branquitude: no delineamento dos grupos raciais que acessaram a educação enquanto direito e como via de acesso ao poder.
Círculos de Cultura: história de uma prática de educação popular (déc. De 1950 – 1960)
Authors: Parise Brandalise Dalsotto Mariana , Luchese Terciane Ângela
Published: November 2019

Resumo: O artigo aborda a proposta de educação popular organizada por Paulo Freire no Brasil no início da década de 1960, explicitando sua historicidade e sua metodologia. Inicialmente explicitamos aspectos da educação no século XX, com ênfase à década de 1950 e início de 1960, indicando a emergência da educação popular. Em seguida, a proposta de prática educacional de Paulo Freire e sua concepção de educação são pensadas a partir das práticas em que se envolvia e da realidade histórica e geográfica na qual estava inserido. Por fim, através da análise documental da imprensa, apresentamos os tensionamentos e disputas em torno da educação na época entendidas como uma luta de representações.
Apresentação do Dossiê
Authors: Bilhão Isabel , Silveira Éder Da Silva
Published: November 2019

Apresentação
Mediación policial. Un protocolo de prevención del delito y cultura de paz
Authors: Steele Garza José Guadalupe
Published: November 2019

La mediación policial, pretende instaurar una nueva orientación en las actividades cotidianas de la seguridad pública. Se postula como una alternativa irreversible frente a las corrientes clásicas de la imposición de la pena. La transformación política y social en las comunidades, requiere de nuevas formas de acción operativa para satisfacer la seguridad pública. La mediación policial es viable y factible para la reconstrucción de relaciones interpersonales e intergrupales que fortalece el capital social, previniendo las conductas antisociales. La mediación policial supone un nuevo protocolo de intervención más proactivo que reactivo, que atiende y entienda las diferencias de la comunidad, pero con énfasis a la cultura del dialogo y sana convivencia.
Türkiye Tarım Kredi Kooperatifleri için Kurumsal Performans Karnesi Önerisi
Authors: FASAL Abdulkadir , BALABAN Özlem
Published: November 2019

Bu çalışmada, ülkemiz tarım sektörü açısından
önemli konumda bulunan kooperatiflerin kurumsal performanslarında artış
sağlayacak, yöneticiler için karar verme süreçlerine katkıda bulunacak ve
kooperatiflerin kendi yapılarına uyarlayarak kullanabilecekleri çok boyutlu
ölçme ve değerlendirme sistemini baz alan kurumsal performans karnesi
oluşturulması amaçlanmıştır.  Çalışma kapsamında
verilerin elde edilmesinde kullanılan anket formu yöneticilerden oluşan 5
kişilik bir çalışma grubu ile yapılan 9 haftalık çalışmalar sonucu
oluşturulmuştur. Sonrasında anket formu Tarım Kredi Kooperatifleri Merkez
Birliği ve 17 Bölge Birliğinde çalışan 140 yöneticiye gönderilmiştir.
Yöneticiler tarafından 105 ankete geri dönüş yapılmıştır. Çalışma
sonucunda tarımsal kooperatiflerde finansal ve ortak boyutunun ön planda
olduğu,  öğrenme ve gelişme boyutunun
arka planda kaldığı tespit edilerek, konuya yönelik çözüm önerileri
geliştirilmiştir.
Doğrusal Olmayan Kanonik Korelasyon Analizi ile Seçilmiş Demografik ve Sosyo-Kültürel Kavramların Değerlendirilmesi
Authors: ÖZKAN Mustafa
Published: November 2019

Bu çalışmanın amacı, kategorik değişken gruplarının
değerlendirilmesinde kullanılan önemli yöntemlerden biri olarak bilinen Gifi
terminolojisinin son aşaması olan doğrusal olmayan kanonik korelasyon
analizinin (OVERALS) kullanımıdır. Bu amaçla,  Türkiye'deki bireylerin,
seçilen demografik ve sosyo-kültürel kavramlar açısından farklılık gösterip
göstermedikleri değerlendirilmiştir. Çalışmada, öncelikle OVERALS hakkında gerekli
genel bilgiler verilmiştir. Sonrasında, veriler SPSS 24.0 paket programı ile test
edilmiştir. Araştırma için, Türkiye İstatistik Kurumu (TÜİK) tarafından her yıl
gerçekleştirilen yaşam memnuniyeti anketinin 2017 mikro verileri kullanılmış ve
9876 adet geçerli anket verisinden faydalanılmıştır.  OVERALS sonuçlarına göre, bitirilen okul,
cinsiyet, bilim, moda, ekonomi, spor ve kültür kavramlarının, Türkiye'de
demografik ve sosyo-kültürel açıdan ayırma gücü yüksek değişkenlerdir. Çalışmada
hangi demografik ve sosyo-kültürel kavramlar arasında toplumsal benzerlik ya da
farklılıklar olduğu da değerlendirilmiştir.
Türk Çay Sektöründe Yasal Gelişim ve 1984 Serbestleştirmesi
Authors: SAKLI Ali Rıza
Published: November 2019

Tarihi süreçte, belli alanlardaki yasa değişimlerinin ele alınması,
değişimi gerektiren durumların ve hayata geçirilen uygulamaların izlenmesi
bakımından yarar sağlamaktadır. Türk çaycılığının yasal gelişiminin ele
alınması bir ölçüde ihmal edilmiş sayılabilir. Bu çalışmada, önde gelen çay
yetiştirici ülkelerden Hindistan, Sri Lanka ve Kenya çay yasaları kabaca incelenerek;
üç ülkenin de kapsamlı yasal düzenlemelere sahip oldukları görülmüştür.
Türkiye’de eski tarihli çay yasaları daha kapsamlı olduğu halde, 1984 tarihli
yasanın serbestleştirme (deregulation) kaygısıyla hazırlandığı anlaşılmaktadır.
1984 serbestleştirmesi, çay sektöründe sorunların çözümünü sağlamadığı gibi, birçok
soruna kaynaklık etmiş, özel sektörün kayda değer bir başarı göstermesini de
sağlamamıştır. Bu çalışmada, serbestleşme döneminde yaşanan sorunlar
belirlenmeye çalışılmıştır. Ayrıca bu sorunların çözümü için yeni bir çay
yasası çıkarılması; çay kurulu ve çay borsası kurulması, çay imalatının
standartlara bağlanması, yeni bir yaş çay toplama düzeni kurulması gibi
öneriler getirilmiştir.
Formation of the Integrated Information Environment of a Radio-Electronic Equipment Design
Authors: Drozd Oleg V. , Kapulin Denis V.
Published: November 2019

Widely known method of combining of different information instruments of design support is formation of a common information space. However the modern nomenclature of software for the organization of a common information space not always considers specifics of a radioelectronic equipment production. In article the task on development of a mathematical model for the electronic designer document and formalization of interaction between design tools at all stages of a project cycle of a radio-electronic equipment is researched. The mathematical model of the electronic designer document with using of the subject-oriented ontology apparatus and theory of sets is offered. Dynamics of the electronic designer document life cycle is described by using of the automata theory, graphically the model of dynamics is presented in the form of the oriented graph, simulation modeling of dynamics was carried out in the numerical computing environment MATLAB with using of an extension packet Stateflow. Application area of use of the developed mathematical model is design and tests of digital receivers of navigation satellite signals. The hardware-software automated bench and software of interaction with management system the engineering data “Lotsman: PLM” within a common information space are developed for implementation of tests of the designed digital receiver
Research of the Stress State of the Rail by Three-Exposition Method of Holographic Photoelasticity
Authors: Bryukhovetskaya Elena V. , Konischeva Olga V. , Kudryavcev Ilya V.
Published: November 2019

The description of a method of three expositions, for separate obtaining the main tension by method of holographic photoelasticity with use of two volume models of a rail with inserts from active materials various optically is given. The comparative analysis of experimental data with the analytical solution of a task for a rail which showed good convergence of results is provided
Studies on the Changes, Occurring at the Initial Stage of the Interaction of Btadiene Rubber and its Vulkanized Produkt with Nitric Acid
Authors: Dimov Milen , Taneva Ira , Dimov Ivan
Published: November 2019

The purpose of this work was to study the chemical changes, taking place during the initial stage of the interaction of butadiene rubber and its vulcanized product with nitric acid by means of the differential IR spectroscopy. Thus some mechanistic knowledge, associated with the complex nature of this process could be obtained
Structural-Phase Conditions and Flow Stress at Plastic Deformation of Steel 12Х18Н10Т
Authors: Tussupzhanov Aidyn E. , Yerbolatuly Dosym , Kveglis Liudmila I.
Published: November 2019

The article presents the results of structural and phase transformations and their correlation with microhardness in steel 12X18H10T after thermomechanical treatment and high-temperature plastic deformation. Assessments of the true flow stress during high-temperature uniaxial tension
Non-Reagent Cleaning of Industrial Wastewater, Containing Heavy Metals Based on Technology of Hydrothermodynamic Cavitation
Authors: Dubrovskaya Olga G. , Kulagin Vladimir A.
Published: November 2019

The results of studies on the conditioning systems of industrial wastewater containing heavy metal ions are presented. An analysis of the physicochemical modifications of the component composition of the model runoff has been carried out and the effectiveness of reducing the content of heavy metal ions under various hydrothermodynamic modes has been determined. Methods for mathematical modeling of determining the modes of optimal cavitation treatment of runoff are proposed, the advantages of upgrading cleaning equipment with the inclusion of SC reactors are identified
Before Landing: How Do New European Emigrants Prepare Their Departure and Imagine Their Destinations?
Authors: Coletto Diego , Fullin Giovanna
Published: November 2019

In migration studies, the preparation for the departure of people who decide to migrate has seldom been addressed as a distinct topic. This article aims at investigating how European migrants who moved or plan to move to another European country prepare their departure. It analyses stories of migrants who move from Italy, Spain, Romania, and Bulgaria. More specifically, attention is focused on departure preparation in order to investigate what migrants do before they depart and how the free mobility of work is perceived by Europeans and applied to their migration plans. Different from general statements about European integration and belonging or about obstacles to intra-EU mobility, the analysis of what individuals do in order to get ready to leave their country of origin provides a very realistic idea of how people perceive European Union and the mobility within it.
Linguistic ideologies of students entering an Argentine university
Authors: Casas Ivana , Gurvit Julieta , Pereira Paola Viviana
Published: November 2019

This work is part of the PROAPI Research Project “Reading and writing in the initial cycle of the Universidad Nacional de Avellaneda”. One of the axes developed in it is linguistic diversity in relation to academic writing processes. A significant percentage of our students are in a situation of languages ​​in contact, they can even be considered bilingual in a broad sense (Speranza, 2012). Considering these specificities in the academic field helps prevent linguistic differences from becoming linguistic inequality with the consequence of abandonment of university studies. Therefore, in the first stage of the investigation, we conducted a survey of incoming students, whose partial result we are interested in exhibiting in this work. One of the questions was to describe with a word or phrase a list of languages ​​that were offered in order to identify linguistic ideologies (del Valle, 2007). From the analysis carried out, it is observed that the predominant linguistic ideologies on the Quechua and Guaraní languages are built, on the one hand, in negative terms of emptiness and enigma, as an unknown terrain of which little and nothing can be said, and on the other, in terms affirmative based on the ideas of ethnicity and foreigners.
Approximators and mitigators in Chilean Spanish: the case of 'como' and 'como que'
Authors: Mondaca Becerra Lissette Andrea
Published: November 2019

This article analyses the use of the approximators como and como que in Chilean Spanish, and the link between their approximative semantic value and pragmatic mitigation. Previous works have given the marker como an approximative value (Mihatsch, 2009, 2010; Jørgensen and Stenstrøm 2009; Jørgensen, 2011; Holmvik, 2011; Kornfeld, 2013; Kern, 2014; Jiménez and Flores-Ferrán, 2018), and also a mitigating one (Puga, 1997; Briz, 1998; Jørgensen, 2011; Holmvik, 2011; Kornfeld, 2013, Panussis, 2016; Mondaca, 2017; Panussis and San Martín, 2017). Thus, the objective here is to analyze the relationship between semantic approximation and pragmatic mitigation through these particles, in order to establish whether all those approximative uses of como and como que also perform a mitigating function. Likewise, this paper seeks to propose a general description of those contexts that motivate Chilean speakers to approximate and mitigate their discourse through como and como que. For this purposes, 24 sociolinguistic interviews extracted from the corpus compiled in the Fondecyt Project 11110211 have been used. The main results show that como is a semantic approximator that, in those contexts where the speaker seeks to safeguard his or her face, acquires a pragmatic mitigation function, while como que, on the other hand, is a particle which predominant function is to mitigate.
Virus respiratorios identificados de pacientes hospitalizados en una institución de alta complejidad
Authors: Viola Luz Marina , Pacheco Robinson , Rosso Fernando , Villegas Adriana
Published: November 2019

Introducción: Las Infecciones Respiratorias Agudas (IRA) son un grupo de enfermedades con sintomatología respiratoria similar, causadas por bacterias o virus que se adquieren por contacto directo o a través del aire.

Objetivo: Determinar la prevalencia de virus respiratorios identificados por RT-PCR múltiplex y detección por microarreglos,  en la Fundación Valle del Lili entre junio de 2013 y diciembre de 2014.

Métodos: Realizamos un estudio observacional descriptivo de corte transversal, se evaluaron registros de pacientes hospitalizados en la FVL entre junio de 2013 y diciembre de 2014. Las muestras fueron evaluadas por RT-PCR múltiplex y detección por microarreglos (CLART PneumoVir), se aplicó estadística descriptiva.

Resultados: De 161 muestras, 96 (60 %) fueron positivas. El servicio con la mayor proporción de pacientes positivos fue la Unidad de Cuidados Intensivos-UCI (56%). El 32 % de los aislamientos positivos se identificaron en pacientes mayores de 60 años. Los virus más frecuentemente detectados fueron: Rinovirus (30%), Influenza (H1N1/ 2009) (12 %) y Bocavirus (12 %). Influenza A (H1N1/2009) fue la cepa más comúnmente aislada entre los virus de la gripe (12%), seguido de un 11% (17 casos) con coinfección viral. No se identificó el patrón estacional.

Conclusión: La RT-PCR múltiplex y la detección por microarreglos para la identificación de los virus de mayor circulación en el mundo, son herramientas útiles, sensibles y rápidas. A diferencia de lo reportado por la literatura científica, en este estudio se observó mayor porcentaje de pruebas positivas en adultos y no se observó estacionalidad para ninguno de los virus evaluados
The Christian Attitude towards Health in John Paul II's Teaching
Authors: Dyrka Anna
Published: November 2019

The issue of health is generally considered to be a domain of medicine. It has to be noted, however, that the conception of medicine is closely connected with the understanding of man's nature. A human person is the place where medicine and theology meet. Theology, drawing on Divine Revelation, brings the truth about the essence of man's nature, and this is why it can influence the way health is understood and the way medicine is practiced. The article presents chosen medical conceptions of health – the bio-medical model and the holistic one, as well as the understanding of health in the theological perspective – mainly on the basis of John Paul II's teaching (Christian personalistic anthropology). The Christian attitude towards health should be characterized by contemplation of the gift of life, by an ancillary love of the neighbor resulting from love of God, by perception of suffering as a place where God's visit is experienced and as participation in redeeming the world, as well as by hope that concern for life and health is a forecast of resurrection and glory in the eternal life.
Pomoc psychologiczna a modlitwa o uzdrowienie wewnętrzne
Authors: Jastrzębski Andrzej
Published: November 2019

W procesie uzdrowienia wewnętrznego biorą udział różnorodne czynniki. Bogactwo tych czynników wskazuje na niezwykłą złożoność bytu ludzkiego, w którym napotykamy zarówno elementy duchowe jak i biologiczne. Szczególne miejsce w tym względzie zajmuje psychika człowieka, która stanowi łącznik różnych sfer bytu ludzkiego.
W niniejszym artykule poddamy analizie różne metody prowadzące do uzdrowienia wewnętrznego człowieka. W szczególności porównamy pomoc psychologiczną oraz modlitwę o uzdrowienie wewnętrzne. Postaramy się ukazać odmienność obu tych podejść poprzez analizę ich celu oraz metod, wskażemy na różnice metodologiczne oraz przedyskutujemy możliwą współpracę dla dobra człowieka cierpiącego.
Uzdrowienia Boskie a uzdrowienia demoniczne
Authors: Zalewski Sławomir
Published: November 2019

W chrześcijaństwie istnieją nadzwyczajne uzdrowienia, których przyczyną jest Bóg. Dokonują się one w określonym kontekście religijnym i modlitewnym oraz zakładają otwartość iwiarę podmiotu, który pragnie odzyskać utracone zdrowie. Musi on dokonać aktu przebaczenia w imię Jezusa, ażeby mógł bez przeszkód przyjąć dar uzdrowienia. Ten dar dotyka zawsze całego człowieka i uzdrawia również jego ducha. Człowiek przeżywa głębiej swoją wiarę, doświadcza gorętszej miłości Jezusa oraz nowości życia, która będzie w pełni osiągnięta wKrólestwie Niebieskim. Istnieją również nadzwyczajne zjawiska, których autorami są demony. Ponieważ są bytami czysto duchowymi, mogą przekazywać ludziom im oddanym swoje moce w postaci np.: nadzwyczajnej siły; lewitacji; nienaturalnego ciężaru ciała; recytowania długich passusów książek, których nigdy nie czytali; retroskopii. Wśród tych nadzwyczajnych zjawisk występuje również fenomen uzdrawiania. Demony potrafią zainfekować człowieka chorobą i usuwać jej objawy. Potrafią także usuwać symptomy chorób naturalnych, posługując się uzdrowicielami jako swoimi narzędziami. Chory może doświadczyć efektów pozytywnych w wymiarze fizycznym, lecz zawsze musi zapłacić za to cenę w postaci pojawienia się gorszej choroby, trudności duchowych, pogorszenia albo zniszczenia więzów rodzinnych czy społecznych i otwarcia szeroko drzwi na działanie osobowego zła w rodzinie. Są to ciężkie konsekwencje, które muszą ponosić ludzie ulegający podstępnemu działaniu demonów.
Miłosierdzie Boże w relacji do kapłaństwa i formacji kapłańskiej
Authors: Ciereszko Henryk
Published: November 2019

Artykuł podejmuje problematykę związku prawdy miłosierdzia Bożego z kapłaństwem głównie w aspekcie jej wpływu na kształt kapłaństwa i formację kapłańską. Kapłaństwo sakramentu święceń wprowadza w szczególną więź z Bogiem w Jego trynitarnej tajemnicy, upodabnia do Chrystusa Arcykapłana, uzdalnia i zaprasza do naśladowania Go w postawie i misji wobec Kościoła. Przeżywanie tej więzi z Bogiem, który jest Ojcem miłosierdzia, z Chrystusem, który uosabia i urzeczywistnia miłosierdzie Ojca jako Arcykapłan „wiarygodny i miłosierny” oraz z Duchem Świętym, w mocy którego w Kościele rozdzielane są łaski zbawcze w posłudze kapłańskiej jako dary miłosierdzia Bożego, nie może nie ujawniać w samym życiu i posłudze prezbiterów rysu miłosierdzia. Stąd też w autentycznym i owocnym przeżywaniu swego kapłaństwa prezbiterzy winni dostrzegać znaczące odniesienia miłosierdzia Bożego i kapłaństwa, zgłębiać tajemnicę Bożego miłosierdzia, zwłaszcza w relacji do kapłaństwa, rozwijać nabożeństwo do miłosierdzia Bożego, naśladować to miłosierdzie w swej posłudze kapłańskiej, czyli niejako formować siebie stale także w świetle tajemnicy miłosierdzia Bożego.
The Measures of Modernity: The New Quantitative Metrics of Historical Change Over Time and Their Critical Interpretation
Authors: Guldi Jo
Published: November 2019

What can digital methods tell us about modernity? This article reviews a series of recent traditional and quantitative attempts to define ‘modernity’ in the nineteenth century. Mass digitization allows scholars to track modernity through counts of words per year, the study of discourses (through topic modelling), and relative statistical expression over time (through divergence measurement). The results of this work confirm recent scholarship in social history that demonstrates the rising importance of meat, other food and water to national policy, as well as understudied debates on the history of fisheries. It also demonstrates that different parties in parliament had different relationships to futurity. A case study compares Liberal and Conservative party relationships to past and future through an overview of particular speakers’ lexicons. As a survey of methods, this article’s conclusion is that digital methods can demonstrate not only shifting values, but also require us to think about different relationships to chronology and periodization of individuals and ideas embedded in the past.
As plantas e seus usos nos quintais de Alta Floresta, Mato Grosso
Authors: Silva Jociane Rosseto de Oliveira , Silva Ivan Cleiton De Oliveira , Coelho Maria de Fatima Barbosa , Camili Elisangela Clarete
Published: November 2019

As plantas dos quintais urbanos são utilizadas para múltiplas finalidades, com destaque para as espécies alimentícias e medicinais. O objetivo do presente estudo foi realizar o levantamento das espécies vegetais e seus respectivos usos nos quintais de dois bairros em Alta Floresta, estado de Mato Grosso e estabelecer o perfil dos informantes. Na seleção dos entrevistados aplicou-se a amostragem bola de neve, onde foram utilizadas as técnicas de observação direta e participante, sendo os principais envolvidos na manutenção dos quintais indagados sobre o manejo das plantas e as partes utilizadas para cada uso. Foram observados 99 táxons pertencentes a 49 famílias botânicas. As famílias mais frequentes foram Lamiaceae, Fabaceae e Myrtaceae. As espécies Cocos nucifera L., Myrciaria cauliflora (Mart.) O.Berg e Lippia alba (Mill.) N.E.Br. ex P. Wilson estavam presentes em 50% dos quintais. As categorias de uso citadas pelos informantes foram: a) arborização; b) condimentar; c) cultivo; d) frutífera; e) medicinal e f) paisagismo. Mais de 50% das espécies destina-se ao uso alimentício, destacando a função de segurança alimentar dos quintais. A segunda categoria com maior número de espécies foi a de uso medicinal com 29 táxons, pertencentes à 17 famílias e, Lamiaceae foi a família com maior número de espécies usadas. O uso medicinal mais citado foi na forma de decocção (chá) para gripes e resfriados.
Produção de pimentão em ambiente protegido com água residuária
Authors: Carvalho Pedro Henrique Máximo de Souza , Silva Jamerson Da Silva e , Silva Rodrigo Rafael da , Costa William Ralf Santos , Queiroz Sérgio Oliveira Pinto de , Rocha Ruy De Carvalho
Published: November 2019

Objetivou-se estudar o desempenho agronômico do pimentão cv. Ikeda, irrigado com diferentes qualidades de água, sob dois métodos de manejos de irrigação: reflectometria no domínio da frequência e tensiometria, sob ambiente protegido. O delineamento estatístico utilizado foi o inteiramente casualizado, em esquema de parcelas subdivididas, constituído de três qualidades de água nas parcelas, e dois manejos de irrigação nas subparcelas. Foram avaliadas a produtividade total; produtividade comercial; eficiência do uso da água; massa média dos frutos; comprimento; diâmetro; relação comprimento/diâmetro; teor de sólidos solúveis; acidez titulável e pH. Os resultados obtidos permitem concluir que a produtividade e qualidade físicas dos frutos de pimentão não foram afetadas pela qualidade da água de irrigação, enquanto a menor demanda hídrica quantificada pela tensiometria influenciou significativamente apenas nos pH dos frutos.
Blends de frutos tropicais à base de tamarindo
Authors: Gadelha Maria Rejane De Abrantes , Gomes Jaqueline De Sousa , Silva Amanda Kelly Da , Alves Maria Jaizia Dos Santos , Santos Adriana Ferreira do
Published: November 2019

Um dos recursos à disposição da indústria para a produção de bebidas com novos sabores, coloração atraente, textura e valor nutricional é o desenvolvimento de suco ou néctar de frutos. O objetivo do trabalho foi avaliar a qualidade de polpas e néctares e a partir dessa avaliação, desenvolver blends de frutos tropicais quantificando-os em relação aos aspectos físico-químicos e compostos bioativos presentes. A partir das polpas dos frutos do tamarindo, abacaxi, acerola e maracujá, foram elaborados néctares com 30% de polpa e 70% de água mineral, utilizados como matrizes para a elaboração de sete formulações de blends. As polpas, néctares e blends foram submetidos a análises físico-químicas (sólidos solúveis, acidez, pH e ratio) e de compostos bioativos (ácido ascórbico, clorofila, carotenoides, antocianinas, flavonoides e polifenóis extraíveis totais). O pH das polpas, néctares e todas as formulações apresentaram valores abaixo de 4,5. A polpa e o néctar de acerola apresentaram o maior teor de ácido ascórbico, clorofila, antocianinas e polifenóis extraíveis totais. A Formulação 7 (30% tamarindo + 20% abacaxi + 25% acerola + 25% maracujá) apresentou o maior teor de acidez titulável, ácido ascórbico, antocianinas, flavonoides e carotenoides. A Formulação 4 (30% tamarindo + 30% abacaxi + 30% acerola + 10% maracujá) foi a que apresentou o maior teor de polifenóis extraíveis totais.
Percepção de povos tradicionais do Cerrado sobre a implantação do Parque Nacional da Chapada das Mesas, Maranhão
Authors: Silva Maria Lindalva Alves da , Araújo Maria de Fátima Veras , Conceição Gonçalo Mendes da
Published: November 2019

O Parque Nacional da Chapada das Mesas, foi criado em 2005, com objetivo de proteger a diversidade florística, faunística, espécies endêmicas, atributos naturais, como a presença de 400 nascentes de rios e morrarias esculpidas pelo processo de intemperismo natural presentes na região conhecida como Chapada das Mesas localizada no domínio fitogeográfico de Cerrado, no Sul do Maranhão, Brasil. Alguns aspectos a serem abordados quando se cria uma unidade de conservação são os conflitos gerados pela limitação da exploração dos recursos naturais pelos moradores do lugar, onde se implantará áreas protegidas e a questão fundiária. Neste sentido, a pesquisa teve como objetivo investigar a participação dos moradores no processo de criação do Parque Nacional da Chapada das Mesas. A pesquisa foi descritiva, com aplicação de formulários a 40 moradores. Verificou-se que 77,5% residem no Parque antes de sua criação, 75% não participaram do projeto de implantação da unidade de conservação e 50% foram contra. Com a perspectiva de as famílias ficarem morando dentro do Parque e com a elaboração do Plano de Manejo, espera-se que os moradores compreendam a importância do Parque Nacional para preservação desse ecossistema e passe a apoiar sua implantação.
Extratos de pimentão vermelho (Capsicum annuum) sobre Colletotrichum gloeosporioides in vitro
Authors: França Kevison Romulo da Silva , Paiva Yaroslávia Ferreira , Azevedo Plínio Tércio Medeiros de , Nóbrega Lídia Pinheiro da , Silva Everton Vieira da , Cardoso Tiago Augusto Lima
Published: November 2019

O presente estudo avaliou o potencial fungitóxico in vitro de extratos de pimentão vermelho (Capsicum annuum L.) sobre o crescimento micelial de Colletotrichum gloeosporioides. O experimento foi conduzido em delineamento inteiramente casualizado em esquema fatorial 2x10, sendo dois tipos de extratos (etanólico e hidroetanólico) aplicados em 10 concentrações (0,0; 0,2; 0,4; 0,6; 0,8; 1,0; 2,0; 3,0; 4,0; e 5,0%). Cada extrato foi incorporado ao meio de cultura BDA (Batata Dextrose Ágar) e vertido em placas de Petri. As placas foram inoculadas com discos de 1 cm de diâmetro contendo micélios do fungo e incubadas durante sete dias a 27±2°C. Para verificar a diferença entre os tratamentos, foram estimadas a porcentagem de inibição de crescimento micelial (PIC) e o índice de velocidade de crescimento micelial (IVCM). Todas as concentrações dos dois extratos de pimentão apresentaram inibição do crescimento micelial de C. gloeosporioides quando comparados à testemunha. A inibição total do crescimento foi obtida quando se utilizou o extrato etanólico na maior concentração (5,0%) e ultrapassando 50% de inibição na concentração de 2%, sendo superior à obtida pelo extrato hidroetanólico que na concentração máxima inibiu apenas 27,5% do crescimento do fungo. Assim, em condições in vitro, o extrato etanólico de pimentão vermelho mostrou-se promissor no controle de C. gloeosporioides. A concentração de 5,0% promoveu o maior efeito inibitório.
ANALYSIS OF EXPERT VALIDATION ON DEVELOPING FACTORS INFLUENCING CAREER CHOICE MALAYSIAN VOCATIONAL COLLEGE TEACHERS’ MODEL
Authors: Mutalib M. R. Abdul , M. I. Mahmud , Affandi, H. Mohd , I. Irawan , Rus R Che
Published: November 2019

Purpose of study: The teaching profession is often seen as a non-rewarding career due to high burden duties that the teachers must endure. Consequently, many teachers lose interest in teaching, which resulted in a lack of job satisfaction. However, this profession has been chosen due to intrinsic, extrinsic and altruistic motivation. In view of this, there are some factors that are not explored in depth in a teaching career at Vocational Colleges.The purpose of this study is to explore Malaysian Vocational College teachers’ career choice. The goals of this research are to discover factors that lead Malaysian Vocational College teachers to pursue teaching and to identify the sub-factors in preparing them to be vocational teachers.

Methodology: The development of the constructs Malaysian Vocational College teachers’ career choice is based on 114 literature review articles. This goal is accomplished through 5 panels of experts consensus through the online questionnaires. Online questionnaires are chosen to conduct the survey because of its good review and user-friendliness. All levels of the agreement will be elevated by using the Fliess Kappa (K ) because more than 2 respondents. Fleiss Kappa is then used to evaluate the level of agreement between the raters.

Result: There are six major key factors found: family influence, socio-cultural influence, individual, situational and spiritual. There are 130 items developed and the overall finding K value is 0.55. Nevertheless, the K value within six major key factors is 0.4 to 0.86. The expert panels agree that this questionnaire might be acceptable with some improvement based on their additional comments in the online form. Based on this validation process, this questionnaire can be used in selecting the quality of Malaysian Vocational College teachers or TVET instructors. For the next step, this questionnaire will be conducted on 52 excellent teachers at Malaysian Vocational Colleges to understand in depth the key factors that significantly influence the decision of an individual to enter the vocational teaching profession in Malaysian Vocational Colleges.

Implications/Applications:  In the future, the findings on this research will expose rich sources on the field of teaching and will be helpful to identify some high-quality TVET teachers in Malaysian Vocational College.
REFLECTION OF LABOR MARKET INTERESTS AND EXPECTATIONS IN EDUCATIONAL ORDER FOR CONTEMPORARY SCHOOL
Authors: V. Rogach Olga , V. Frolova Elena , M. Ryabova Tatyana , A. Vetrova Ekaterina
Published: November 2019

Purpose of the study: The main objective of the study was the analysis of key labor market request content for the secondary education system, the level of employers' expectations compliance and actual learning outcomes, the research of resources and partnership interaction limitations of all interesting subjects in the process of an educational order development.

Methodology: The main method was the questionnaire survey of experts (individual entrepreneurs, the heads of industrial and structural divisions) of Moscow (N = 316). The results of the expert survey showed the interest of employers in close cooperation with school in order to reflect the interests of the labor market in the educational order adequately.

Results: The most motivated group is a small business, the leaders of the lowest level in the sphere of trade and service, who directly interact with the school graduates in the process of their early start of labor activity. The experts noted the problems in the development of the social competencies among schoolchildren: excessive self-esteem, an excessive level of claims, low level of willingness to work in a team, the lack of such qualities as responsiveness and responsibility. The cooperation between school and employers is limited to traditional sponsorship practices. The interaction of employers and educational institutions is quite fragmentary, it depends on a variety of random factors (personal and situational motives), which does not ensure the stability and the effectiveness of social partnership.

Applications of this study: This research can be used for the universities, teachers, and students.

Novelty/Originality of this study: In this research, the model of Reflection of Labor Market Interests and Expectations in Educational Order for Contemporary School is presented in a comprehensive and complete manner.
ADAPTIVE POTENTIAL ASSESSMENT OF FUTURE TEACHERS AT THE FIRST STAGE OF THEIR PROFESSIONAL TRAINING
Authors: N. Voloshina Lyudmila , K. Buslovskaya Lyudmila , Ju. Kovtunenko Alexey , P. Ryzhkova Yulia , A. Prokopenko Yulia
Published: November 2019

Purpose of the study: The topicality of the research is determined by the social order for a healthy personality, awareness of education possibilities to improve the adaptative potential, competitiveness, and activity.

Methodology: The assessment of the health state was based on the medical examination results in the clinic of Belgorod National Research University. Somatometric, somatoscopic and physiometric methods were used to define the functional state of the students’ organism.

Results: The health of a growing person starts with the health of his family and the teacher. The quality of the pedagogical strategy and the tactics of healthy generation education are defined by the teacher’s ability to design a personal model of safe behavior and to assess his own health adaptive risks and students too. Adaptative potential assessment of a future teacher as an integral health indicator at the primary stage of his professional training will determine the measures to prevent misadaptation and design strategies for personal safe behavior.

Applications of this study: This research can be used for the universities, teachers, and students.

Novelty/Originality of this study: In this research, the model of the Adaptive Potential Assessment of Future Teachers at the First Stage of their Professional Training is presented in a comprehensive and complete manner.
DIAGNOSTICS OF PROBLEMS OF REPRODUCTION OF PROFESSIONAL POTENTIAL OF THE STATE AND MUNICIPAL MANAGEMENT AS A PRECONDITION OF ITS SYSTEM RENOVATION
Authors: M. Zaharov Viktor , V. Bykhtyn Oleg , I. Gulyaev Ivan , V. Shevchenko Natal'ya , V. Selyukov Maksim , N. Shmigirilova Larisa
Published: November 2019

Purpose of the study: This article deals with the renovation system of reproduction of professional potential and provides a definition of this concept.

Methodology: The study uses the methods of dialectical contradiction, the ascent from the abstract to the concrete, structural-functional and comparative analysis, theoretical modeling and generalization. Primary sociological information is collected through a questionnaire survey, document analysis, free interview, and observation. Methods of grouping and classification of empirical data, qualitative analysis of factors are also used.

Results: the renovation system of reproduction of the professional potential of a state municipal government involves the diagnosis of its problems with the aim of determining the ways of their resolution. The conducted diagnostics identified six groups of actual problems, namely lack of professionalism, the disintegration of indicators of individual and institutional efficiency, the imperfect system of training and advanced training of managerial personnel, the weak motivation of their professional development, inefficient use of professional potential, and passive personnel policy

Applications of this study: This research can be used for the universities, teachers, and students.

Novelty/Originality of this study: In this research, the model of Diagnostics of Problems of Reproduction of Professional Potential of the State and Municipal Management as a Precondition of Its System Renovation is presented in a comprehensive and complete manner.
Mesanenin Nadir Benign Neoplazmı: Mesane Leiomyomu
Authors: BABA Dursun , BAŞARAN Ekrem , KAYIKÇI Muhammet Ali
Published: November 2019

Mesanenin benign mezenşimal lezyonları oldukça nadirdir ve tüm mesane tümörlerinin %1-5’inin oluştururlar. Bunların içinde de en sık leiomyoma saptanmaktadır. Benign lezyonlar radyolojik olarak maling kitleleri taklit etmesi nedeniyle klinik öneme sahiptir. Tanı radyolojik tetkiklerle kitlenin saptanması ve sonrasında yapılan cerrahi eksizyon ya da biyopsi ile histopatolojik olarak konulmaktadır. Ekstravezikal ve intramural form sistoskopik olarak saptanamayabilirken intravezikal leiomyomlar sistoskopi ile saptanabilir. Sistoskopi sırasında mesane içinde protrüde, kısmen düzgün sınırlı ve yüzeyi mesane mukozası ile kaplı lezyonlar görüldüğünde mesane leiomyomu ayırıcı tanıda düşünülmelidir. 44 yaşında kliniğimize irridatif semptomlarla tarafımıza başvuran ve mikroskopik hematüri saptanan erkek hastada mesanede 2x2 cm kitle saptandı. Minimal invaziv tedavi (TUR-mesane) sonrasında leiomyoma tanısı konulan vaka sunulmaktadır.
El tercero del juego
Authors: Bettendorff María Elsa
Published: November 2019

Desde un análisis crítico, la autora afirma que la divulgación masiva de los avances de la tecnociencia, y el territorio del saber legítimo aparentan abrir sus fronteras al ciudadano, sin embargo la distancia entre el conocimiento general y el conocimiento especializado constituye una brecha que obtura la realización armónica del proceso social. En la búsqueda de una justificación tentativa para la imbricación entre teoría y praxis sitúa, desde un punto de vista semiótico la noción de relación, a través de un tercer elemento vinculante, la creatividad o la imaginación creadora. Sobre el foco de la creatividad sustenta la posibilidad del sujeto de indagar por sí mismo acerca de su entorno y sus condiciones de existencia.
Arte y tecnología
Authors: Chalkho Rosa
Published: November 2019

Esta publicación reúne investigaciones de autores que provienen de diversos quehaceres del campo delarte: La composición musical, la curaduría de arte y la gestión cultural. Sus ensayos están atravesados poruna enunciación de la impronta tecnológica en el arte de los últimos tiempos. A través de diversos recorridosla publicación en su conjunto condensa las problemáticas y reflexiones que transitan los discursos del artey en especial de aquellos formatos, artistas y obras posicionados en las puntas experimentales. Este artículoa modo de introducción retoma aquellos conceptos claves expresados por los autores intentando producira partir de ellos un tejido conceptual de vinculaciones, en el marco de la intensa reflexión que en generalcaracteriza a las prácticas artísticas en la actualidad.
Las artes mediáticas interactivas corroen el alma
Authors: La Ferla Jorge
Published: November 2019

El ensayo revela las diversas alternativas y problemáticas del arte en la actualidad, especialmente de lastendencias de fuerte impronta tecnológica, desde el video arte hasta las manifestaciones digitales. Desde laperspectiva del análisis de la circulación y legitimación de obras y artistas en reconocidos festivales, bienalesy concursos internacionales, se reflexiona acerca del campo de las políticas culturales como espacios en crisisfrente a los grandes cambios del denominado espacio público. El texto plantea una mirada crítica de losfactores económicos y políticos dominantes y su relación con lo tecnológico. Dentro de este contextovincula la producción e inserción en el entramado cultural de las recientes manifestaciones del arte ydelibera acerca del campo del arte y el rol en el contexto social de la gestión cultural y la curaduría.
The study of the frequency of buccal epithelium cells with nuclear in athletes in dependence on the place got in the competition
Authors: Kalaev Vladislav N. , Nechaeva M. S.
Published: November 2019

Cytogenetic homeostasis ofathletes involved in hand-to-hand armyfighting, depending on the outcome of the fight and the level of aggressiveness has been studied. Status of the genetic apparatus in athletes was evaluated in buccal epithelium with the use of micronucleus test, which is widely usedfor the determination of the influence of various factors on the genetic stability of the organism. Psychological testing of athletes was executed with the use of Spielberger’s State-Trait Anger Expression Inventory scale, Bass-Darky questionnaire for the diagnostics of aggression and hostile reactions, Eysenck Personality Questionnaire test for the evaluation ofpsychic conditions and method of U.P. Ilyin and P.A. Kovalev for the identification of the propensity to conflictness and aggressiveness (positive and negative) as the personal characteristics. The place taken by the athlete on the competition was shown to have an impact on the frequency of buccal epithelium cells with nuclear abnormalities (micronuclei, perinuclear vacuoles, notches, protrusions "tongue" and "broken egg”). Losers have nuclear aberrations more than winners. At that in athletes with higher aggressiveness and its attendant psychological characteristics the influence of the outcome of the competition on the number of cells with aberrations core is more pronounced.
The application of complex assessment of the health status of the population in tasks of the improvement of the socio-hygienic monitoring system
Authors: Aydinov G. T. , Marchenko B. I. , Sinelnikova Yuliya A.
Published: November 2019

Improvement and unification of information and analytical technologies is the one of the priorities, the solution of which will provide the gain in the efficacy and appropriateness of management decisions, developed preventive and wellness measures. In the article there is explained the use of generalized indices of the real risk as criteria for the comprehensive assessment of the health state of the population at the regional and the municipal levels. The proposed criteria make it possible to increase the objectivity of the assessment of the health state in the sociohygienic monitoring system and in the implementation of the special studies of epidemiological type. There are presented results of a comprehensive assessment of the health state of the population in the cities of Rostov region for the ten-year period and according to socio-hygienic monitoring in 2014 year. In terms of twenty of markers characteristics ofpopulation health there were used indices of the total mortality and morbidity rate. There was executed the complex assessment of the cancer prevalence rate in the urban population on nine priority localizations of the malignant tumors, including stomach, colon, rectum, lungs, skin, mammary gland, corpus uteri, ovary and thyroid gland. There were identified territories of high and elevated real risk to health state of the population. There is presented the result of the application of mathematical modeling used for the assessment and prediction of the impact of environmental factors on the complex assessment of the health staty of the population. Results of research were used for the shaping of information and analytical materials in the Rostov region.