bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of Non-Invasive Cerebral Blood Flow Monitoring Modalities in Adults Undergoing Extracorporeal Membrane Oxygenation
Authors: Dar Irfaan A. , Khan Imad R. , Maddox Ross K. , Prasad Sunil M. , Selioutski Olga , Donohue Kelly L. , Abramson Kenneth , Yodh Arjun G. , Durduran Turgut , Busch David R. , Choe Regine
Published: May 2020

Effects of extracorporeal membrane oxygenation (ECMO) treatment on brain health are currently unknown. For this study, we will noninvasively monitor these patients with diffuse correlation spectroscopy and transcranial doppler ultrasound during ECMO treatment.
Dual-slope method for focal depth sensitivity enhancement in near-infrared spectroscopy
Authors: Sassaroli Angelo , Blaney Giles , Pham Thao , Fernandez Cristianne , Fantini Sergio
Published: May 2020

We propose to use frequency-domain near-infrared spectroscopy data in combination with a special arrangement of two sources and two detectors, to achieve stronger and more spatially confined sensitivity to deeper tissue than using single-distance data.
Wide field mapping of cell-specific contributions to brain function
Authors: Lee Joonhyuk , Bice Annie R. , Bauer Adam Q.
Published: May 2020

We will review our lab’s work using optogenetics and wide field optical imaging for examining excitatory and inhibitory contributions to neurovascular coupling, and how these cell populations are connected across the cortex.
Multi-modality X-ray/Optical Tomographic Imaging Guided Radiotherapy Research Platform: In Vivo Optical Background Subtraction for Sensitive Tumor Detection
Authors: Shi Junwei , Yang Yidong , Udayakumar Thirupandiyur S. , Ahmad Anis , Marples Brian , Dogan Nesrin , Ford John Chetley , Pollack Alan
Published: May 2020

Multi-modality x-ray CT and optical molecular imaging with effective background subtraction enables specific and sensitive tumor detection, which is critical for precise small animal image-guided irradiation and early treatment response assessment.
Optical Methods for Non-Invasive Assessment of Arteriole Flow Impedance
Authors: Yang Jason , Ruesch Alexander , Kainerstorfer Jana M.
Published: May 2020

Cerebrovascular impedance relates vascular flow dynamics to pressure changes and has been challenging to be measured in the microvasculature. We present a method to measure impedance using diffuse correlation spectroscopy (DCS) and near-infrared spectroscopy (NIRS).
All-Optical Electrophysiology in iPSC-Derived Neurons with Synthetic NIR Voltage Reporter
Authors: Puppo Francesca , Sadegh Sanaz , Trujillo Cleber A. , Thunemann Martin , Campbell Evan , Vandenberghe Matthieu , Miller Evan W. , Bloodgood Brenda L. , Djurovic Srdjan , Andreassen Ole A. , Muotri Alysson R. , Devor Anna
Published: May 2020

We demonstrate a robust and reproducible protocol to achieve all-optical electrophysiology in human iPCS-derived and primary cell cultures using synthetic voltage sensors and genetically encoded optogenetic actuators while minimizing cell death due to viral transfection.
Laser pulse shaping to increase brain blood flow sensitivity of time-domain diffuse correlation spectroscopy
Authors: Carp Stefan A. , Peruch Adriano , Tamborini Davide , Mazumder Dibbyan , Wu Melissa M. , Chan Suk-Tak , Robinson Mitchell , Qu Jason Z. , Delpont Guillaume , Schoenau Thomas , Bourdon Alain , Franceschini Maria A.
Published: May 2020

Time-domain diffuse correlation spectroscopy (TD-DCS) aims to increase cerebral blood flow (CBF) sensitivity by discriminating photon time of flight. We report on the optimization of the laser pulse shape to maximize TD-DCS performance.
Multi-channel ultrasound detection via optical phase modulated pulse interferometry
Authors: Hazan Yoav , Rosenthal Amir
Published: May 2020

Optical detection of ultrasound using high Q-factor resonators lack of scalable scheme. In this work, we present phase-modulated pulse interferometry, a scalable scheme, enabling interrogation of multiple resonators simultaneously.
Computational Evaluation of Ethnic Differences in Photothermal Damage induced by Laser Skin Treatments
Authors: SHIMOJO Yu , NISHIMURA Takahiro , HAZAMA Hisanao , OZAWA Toshiyuki , AWAZU Kunio
Published: May 2020

Photothermal damages in laser skin treatments were evaluated computationally to analyze differences between ethnic groups. Our results revealed the seriousness of photothermal damage was varied between the ethnic groups even on the same irradiation conditions.
Effect of Breast Contour and Optode Coupling Error on Ultrasound-guided Diffuse Optical Tomography
Authors: Li Shuying , Zhang Menghao , Uddin K M Shihab , Zhu Quing
Published: May 2020

A finite element method (FEM) and experiment on phantoms were used to study the influence of breast contour mismatch and probe-tissue coupling mismatch in ultrasound-guided diffuse optical tomography for breast cancer imaging.
Baseline Correction for Biomedical Raman Spectroscopy: Where the Fluorescence Stops and the Raman Begins.
Authors: Fillioe Seth , Peterson Charles M. , Chaiken J.
Published: May 2020

Biomedical applications of Raman spectroscopy must separate fluorescence/phosphorescence from the Raman emission. Two “baseline correction” approaches appear in the literature with success. A recent study [1] suggests that one may be advantageous over the other.
Resin-based optical phantom approximating the absorption spectrum of human tissue
Authors: Yoshimoto K. , Ohmae E. , Suzuki H. , Homma S. , Suzuki N. , Wada H. , Mimura T. , Yamashita Y. , Ueda Y.
Published: May 2020

We propose an epoxy resin-based optical phantom containing six dyes, which approximates the absorption spectrum of human tissue over the wavelength range of 700–850 nm.
Different photosensitizers distribution in Paramecium caudatum Ehrenberg, 1838.
Authors: Grishacheva T.G. , Faizullina D.R. , Muslimov A.R. , Chistyakova L.V. , Korneva E.A , Petrishchev N.N.
Published: May 2020

Ciliates is a promising object for the accumulation and distribution studies of new photosensitizers in the cell by laser confocal scanning microscopy. Data of Radachlorin, Bengal rose and Coproporphyrin III in the cells is shown.
Quantifying Cerebral Autoregulation in Patients with Sickle Cell Disease Using Near-Infrared Spectroscopy
Authors: Wood Sossena , Fanta Abeselom , Dosunmu-Ogunbi Atinuke , Ruesch Alexander , Jonassaint Jude , Huppert Theodore , Novelli Enrico M. , Kainerstorfer Jana M.
Published: May 2020

This study aimed to quantify cerebral autoregulation (CA) in patients with sickle cell disease (SCD) (n=11) and healthy controls (n=14) using near-infrared spectroscopy. Patients and volunteers performed paced breathing and frequency-dependent phase differences were compared.
Analysis and Characterization of 5-Fluorouracil based on Terahertz Spectroscopy
Authors: Cao Yuqi , Huang Zhangwei , Chen Jiani , Huang Pingjie , Ge Weiting , Hou Dibo , Zhang Guangxin
Published: May 2020

Terahertz time-domain spectroscopy is applied for the characterization of 5-Fluorouracil. The absorption coefficients and refractive indices of 5-Fluorouracil at six concentrations are investigated. The refractive index spectra show a positive correlation trend with sample concentration.
Effects of Different Hardware and Measurement Parameters on Diffuse Correlation Spectroscopy
Authors: Cortese Lorenzo , Presti G. Lo , Giovannella M. , Fischer J. B. , Pagliazzi M. , Zanoletti M. , Mora A. Dalla , Contini D. , Wojtkiewicz S. , Dehgani H. , Weigel U. M. , Durduran T.
Published: May 2020

The precision of diffuse correlation spectroscopy (DCS) measurements was evaluated for varying instrumental and experimental parameters to provide recipes for making practical choices when designing devices.
Towards fast and high resolution hyperspectral single-pixel lifetime imaging with deep-learning
Authors: Ochoa Marien , Rudkouskaya Alena , Barroso Margarida , Intes Xavier
Published: May 2020

We report on a CNN architecture to reconstruct high resolution intensity and lifetime maps based on hyperspectral single-pixel data while decreasing experimental acquisition time by a ~40-fold in preclinical imaging scenarios.
Holographic Projection of Brain Magnetic Resonance Data Based White and Gray matter Segmentation
Authors: Abdelazeem Rania M. , Youssef Doaa , El-Azab Jala , Hassab-Elnaby Salah , Agour Mostafa
Published: May 2020

This study reports on a holographic projection system for brain tissue and its white and gray matter extracted from magnetic resonance data where computer-generated holograms are calculated and projected using a phase-only spatial light modulator.
Topography of alpha rhythms evoked by transcranial laser neuromodulation and thermal stimulation
Authors: Wanniarachchi Hashini I. , Wang Xinlong , Wu Anqi , chaudhari Akhil , Liu Hanli
Published: May 2020

To understand the mechanism of action of transcranial photobiomodulation, we measured and compared alpha rhythms evoked by transcranial laser and thermal stimulations. The two types of stimulations resulted in distinct difference in alpha topographs.
Fast Diffuse Correlation Spectroscopy with a low-cost, fiberless embedded diode laser
Authors: Biswas Arindam , Parthasarathy Ashwin B.
Published: May 2020

We demonstrate that fast blood flow measurement with Diffuse Correlation Spectroscopy (DCS) can be achieved with a small, low-cost, fiber-less single-mode diode laser, that can be embedded into an optical probe.
Laser Machining of a Multicore Fibre for Multipoint in vivo Illumination and Collection
Authors: Chandrasekharan H. K. , McShane E. P. , Dhaliwal K. , Tanner M. G. , Thomson R. R.
Published: May 2020

Ultrafast laser pulses are used to machine a multicore fibre (MCF), such that different MCF cores emit light at different positions. This can be applied to many biomedical applications, such as distributed sensing.
The evolving role of confocal microscopy combined with optical coherence tomography to guide Mohs surgery: early adoption at the bedside
Authors: Rajadhyaksha Milind
Published: May 2020

Advances in pre-operative mosaicking of basal cell carcinoma margins in vivo with combined reflectance confocal microscopy-and-optical coherence tomography and intra-operative margins ex vivo with combined reflectance-and-fluorescence confocal microscopy to guide Mohs surgery will be presented.
Dynamic Tissue Oxygenation Measurements from a Hand-Held Near-Infrared Optical Scanner (NIROS): In-vivo Validation Studies
Authors: Leiva Kevin , Robledo Edwin , Ortega David , Wu Wensong , Godavarty Anuradha
Published: May 2020

A hand-held near-infrared optical scanner (NIROS) was developed to acquire spatial and temporal (dynamic) tissue oxygenation measurements, and the measurements validated via in-vivo occlusion studies on controls.
Tracking Breast Cancer Therapies with Handheld and Wearable Diffuse Optics
Authors: Roblyer Darren , Tank Anup , Spink Samuel , Applegate Matthew B. , Ko Naomi
Published: May 2020

We present here our recent clinical data and technological developments in diffuse
optical technologies for monitoring breast cancer at early timepoints.
Clinical Use of Scanning Angle-Resolved Low Coherence Interferometry for Detection of Cervical Dysplasia
Authors: Kendall Wesley , Ho Derek , Chu Kengyeh , Zinaman Michael , Wieland Daryl , Wax Adam
Published: May 2020

We demonstrate the first clinical implementation of a scanning method to perform angle-resolved low-coherence interferometry (a/LCI) to detect cervical dysplasia over a large area without repositioning.
A Novel Portable Fluorophore-free Photonic qPCR for Point-of-Care Applications
Authors: Mohammadyousef P. , Paliouras M. , Trifiro M. , Kirk A.G.
Published: May 2020

Plasmonic-driven Polymerase Chain Reaction is accomplished by a surface-emitting laser with real-time amplification detected via monitoring of DNA-UV transmission. This miniature device provides high amplification efficiency and rapid sample analysis for point-of-care applications.
Development and Translation of intra-Tracheal Multiplexed Sensing Endotracheal Tubes (iTraXS)
Authors: Morgan Stephen P , Correia Ricardo , Korposh Sergiy , Al-Badri Mohammed , Hayes-Gill Barrie R. , Norris Andrew M. , Sinha Rishie , Hardman Jonathan G. , Gardner David S. , Talbot Simon
Published: May 2020

An endotracheal tube with integrated optical fibre sensors (fibre Bragg grating and photoplethysmography) is described. The system aims to ensure the appropriate cuff inflation pressure to achieve a gas seal but reduce pressure injury.
Multimodal Optical Spectroscopy of Functional and Molecular Changes in Tumors after Radiation Therapy
Authors: Dadgar Sina , Paidi Santosh K. , Barman Ishan , Rajaram Narasimhan
Published: May 2020

We present functional and biomolecular changes in head and neck tumor xenografts when exposed to radiation therapy and discuss how these changes can be used to monitor tumor response to therapy.
Intraoperative FLIm on brain tumor margins
Authors: Alfonso-Garcia Alba , Nobel Silvia , Bec Julien , Bobinski Matthew , Lechpammer Mirna , Omofoye Oluwaseun , Bloch Orin , Marcu Laura
Published: May 2020

Fluorescence lifetime imaging (FLIm) is used intraoperatively as a label-free imaging technique to assess brain tumor margins of ten glioma patients. Collection of micro-biopsies at the imaging site allows direct co-registration with histopathological diagnosis.
Diffuse optical evaluation of hemodynamic and metabolic biomarkers towards guiding management in acute ischemic stroke
Authors: Frisk Lisa Kobayashi , Fischer Jonas B. , Alonso Daniel Guisado , Pla Clara Gregori , Jimeno Izaskun Belmonte , de Basea Gomez Anna Bosch , Roman Marta Navarro , Weigel Udo M. , Martí-Fàbregas Joan , Delgado-Mederos Raquel , Durduran Turgut
Published: May 2020

A new hybrid diffuse optical platform was developed with fast, time-resolved and correlation spectroscopied. We present the device and results from an on-going clinical trial to evaluate hemodynamic and metabolic biomarkers for guiding acute ischemic stroke management.
A CMOS-SPAD Array Line Scanning Imaging System for Biophotonic Applications
Authors: McShane E. P. , Chandrasekharan H. K. , Finlayson N. , Erdogan A. , Henderson R. K. , Dhaliwal K. , Thomson R. R. , Tanner M. G.
Published: May 2020

We present a 512 pixel CMOS-SPAD array line scanning imaging system for biophotonic exploitation in the near-infrared. Specifically we discuss utilising this imaging system for the time-resolved study of photon scattering from deep within tissue.
Yes, it is possible! Framing processes and social resonance of Spain’s anti-eviction movement
Authors: Barranco Oriol , Parcerisa Lluís
Published: May 2020

There are few empirical studies on the cultural consequences of social movements. This article contributes to alleviating this problem, examining the cultural outcomes produced by the action of the Platform for People Affected by Mortgages (PAH), one of the most important social movement organizations to appear in Spain in the 2010s. Concretely, through qualitative methods, we analyse the content and form of the PAH’s discourse and the communicative practices developed to disseminate it to the population. Following, we examine this diffusion using quantitative methods. The article shows that PAH activists produced a discourse with a form and content that sought to achieve alignment with the common sense of the majority of the population, that their communicative practices took advantage of the opportunities offered by social and mass media, and, lastly, that the PAH’s diagnosis and proposals resonated among a majority of the population.
Voice, technology and feminist community: An interview with NYX
Authors: Bentivegna Francesco
Published: May 2020

The role of vocality in the field of techno-feminism in performance is undertheorized. The latest takes in posthumanism and eco-feminism wish for a more inclusive, less capitalo-utilitarian use of new technologies. Through the motto ‘make kin, not babies’, the new frontiers of techno-feminism address the anthropo-heterocentric concept of family, hoping for different agglomeration of creatures. Following these stances of feminist and queer critique, it is possible to assume that the work of NYX – an electronic drone choir – addresses vocal composition from an inclusive and posthuman point of view. Through the interview conducted by Francesco Bentivegna with Sian O’Gorman, this voicing explores how the NYX experience might fit in the latest feminist waves, being a shout for a more inclusive, less patriarchal and non-exploited use of technologies.
Primeira classe: como construir uma escola de qualidade para o século XXI
Authors: Hickmann Adolfo Antonio , Hickmann Girlane Moura
Published: May 2020

RESENHA
[SCHLEICHER, A. Primeira classe: como construir uma escola de qualidade para o século XXI. Tradução de Dani Gutfreund e Lenice Bueno. Paris: OECD Publishing; São Paulo: Fundação Santillana, 2019. Disponível em: . Acesso em: 14 ago. 2019.]
Vindicación de las esferas públicas: espacios de crítica para tiempos críticos
Authors: Muñoz Terrón José María
Published: May 2020

El artículo replantea, en confrontación con Reinhart Koselleck, la relación entre tiempos de crisis y esferas públicas, así como la «dialéctica», ahí implicada, entre «secreto» y «publicidad». Desde este marco interpreto la crisis contemporánea de modelos de comunicación y participación políticas, en parte por el impacto de las TIC, con referencia a fenómenos sociopolíticos recientes en España, como el movimiento 15M o el nuevo partido Podemos. La crítica genera o agudiza las crisis y éstas se expresan en aquella. El ideal de la esfera pública se reconfigura con cada crisis, para confrontar a sociedad y política con el nivel de crisis su tiempo. Frente a Koselleck, reitero la exigencia normativa de esferas públicas como espacios críticos, ámbitos sociales, intermedios entre política y mundo de la vida.
Escape the Planet: Empowering Student Designers to Create a Science-Based Escape Room with Augmented Reality
Authors: Vicari Chris
Published: May 2020

The American Museum of Natural History (AMNH) in New York City implemented a science-based curriculum pairing augmented reality (AR) with a student-designed escape room experience to support astronomy learning. AR has the potential to simplify complex systems into digestible concepts. Designing an escape room experience provided students with an exciting opportunity to apply their understanding of astronomy concepts. This paper (1) presents a background of the curriculum, our development process, and describes the student-design framework, (2) describes the design of the escape room and the activities to facilitate science learning, (3) discusses how we utilized augmented reality in the course (4) presents design issues and revelations, and (5) proposes future changes.
Perbedaan Elektrolit Plasma dan Tekanan Darah antara Preload Ringer Asetat Malat Dibandingkan dengan Ringer Laktat
Authors: Yudhowibowo Ifar Irianto , Sutiyono Doso , Nurcahyo Widya Istanto
Published: May 2020

Latar belakang : Pemberian preload untuk mencegah hipotensi pada anestesi spinal dapat mempengaruhi keseimbangan cairan tubuh.Tujuan : Untuk melihat perbedaan elektrolit plasma dan tekanan darah antara preload RAM dibandingkan dengan RL.Metode : Penelitian eksperimental uji klinis tahap II secara acak tersamar ganda. Pemilihan sampel secara Consecutive Random Sampling didapat jumlah sampel 38 orang. Kelompok I (n=19) mendapat preload 20 cc/kgBB RAM dan kelompok II (n=19) mendapat preload 20 cc/kgbb RL. Sebelum  preload, diambil sampel darah untuk pemeriksaan konsentrasi elektrolit plasma. Setelah  preload dan 30 menit setelah itu dilakukan pengambilan sampel darah untuk pemeriksaan konsentrasi elektrolit plasma. Pengukuran tekanan darah dilakukan sebelum anestesi spinal dan segera setelah anestesi spinal tiap 5 menit sampai 30 menit. Uji statistik dengan uji paired t-test.Hasil : Selisih Na sebelum preload dan Na setelah preload dengan Na 30 menit setelah preload antara kelompok yang mendapat preload RAM dan RL berbeda bermakna. Sedangkan selisih Na setelah preload  dengan Na 30 menit setelah preload berbeda tidak bermakna. Selisih K sebelum  preload, K setelah preload dan 30 menit setelah preload dan K 30 menit setelah preload berbeda tidak bermakna. Selisih Cl sebelum dan Cl 30 menit setelah preload berbeda bermakna. Selisih Cl sebelum dan Cl setelah preload dan konsentrasi Cl setelah 30 menit preload berbeda tidak bermakna. Terdapat perbedaan tekanan sistolik yang bermakna antara kelompok preload  RAM dan RL  terjadi antara menit ke-25 sampai menit ke-30 setelah spinal. Sedangkan untuk variabel tekanan darah diastolik terdapat perbedaan yang bermakna antara kelompok preload  RAM dan RL  terjadi antara menit ke-15 sampai menit ke-20 setelah spinal.Simpulan : RAM meningkatkan konsentrasi Na dan Cl lebih tinggi dibanding RL pada pasien dengan spinal anestesi segera setelah dilakukan loading, tetapi perbedaan konsentrasi elektrolit lebih jauh tidak ditemukan. Tidak ada perubahan tekanan darah yang bermakna diantara kedua kelompok.
Od tożsamości do utożsamienia. Inspiracja psychoanalityczna
Authors: Świrek Krzysztof
Published: May 2020

Modern subject is interested in studying his or her identity, however this act of examination nullifies its object: showing it as problematical or even non-existent, impossible to maintain as coherent entity. As time passes, the problem radicalizes itself, as it is shown in the works of theoreticians of ‘late modernity’: identity is often treated as a project, non-conclusive process of seeking the optimal states of well-being. As the various ‘identity crises’ go on, it is stated in various ways, that even subjectivity itself is waning. Maybe focusing on individual, as someone who has particular identity is not the best way of entangling this knot of problems. Interesting inspirations come from psychoanalysis. Firstly, psychoanalytical theory shows us, that individual with particular traits is not the same, as subject, and that subject is always-already ‘deconstructed’, divided. Secondly, problems with identity may be elucidated, when we turn to psychoanalytical theories of identification. In fact, what we often call ‘identities’ is better to be understood as partial and even theatrical identification with some content. The article shows how certain concepts of Freud and Lacan can be used to clarify complex or even obscure problems that haunt the notion of ‘identity’ as a source of meaning, used by social sciences.

Krzysztof Świrek, Od tożsamości do utożsamienia. Inspiracja psychoanalityczna [From Identity to Identification. Psychoanalytical Inspiration] edited by E. Smolarkiewicz, J. Kubera, „Człowiek i Społeczeństwo” vol. XLIV: Tożsamość i identyfikacje. Propozycje teoretyczne – doświadczenia badawcze [Identity and identifications. Theoretical proposals – research experiences], Poznań 2017, pp. 33-48, Adam Mickiewicz University. Faculty of Social Sciences Press. ISSN 0239-3271.
Cyganie vs Romowie w Hiszpanii. Przynależność etniczna, język i tożsamość
Authors: Biernacka Maja
Published: May 2020

The paper scrutinizes the particularities of the terms Gypsy and Romaní and selected differences between them in the context of the Spanish society. The first notion refers to the ethnicity which has been historically linked with the Iberian Peninsula since the first half of the fifteenth century and the term Romaní is used with reference to nomadic groups mainly from the Balkans. While the notion ‘Gypsy’ has been abandoned in Central and Eastern Europe as disparaging, its equivalent i.e. gitano is legitimate and acceptable in Spain. The article also draws upon some of qualitative research carried out by the author in Spain, i.e. participant observation and unstructured interviews conducted with the Gypsies with a focus on identity and language issues.
Puferi u nastavi. II. Priprema i upotreba
Authors: Dabić Dario , Petrin Damjan
Published: May 2020

U ovom tekstu razmatra se kako odabrati pufer ovisno o svrsi i kako ga pripraviti, pri čemu je navedeno nekoliko načina pripremanja puferskih otopina. Uz naglašeno nužno razumijevanje konstanti disocijacije kiselina, čitateljima se nastoji približiti ispravan način pripremanja željenih puferskih otopina. To se ponajprije odnosi na uzimanje u obzir svih faktora koji mogu utjecati na neki puferski sustav. U tekstu se zato obrađuju važni pojmovi i povezuju s njihovim primjenama u znanstvenom i inženjerskom svijetu. Također, pojašnjava se pojam kapaciteta pufera i njegova uloga, pojam ionske jakosti te na što ona utječe. Navedena su bitna svojstva koja pufer treba imati te kako produljiti trajanje puferskih otopina. Na kraju se može provjeriti što su zapravo puferi te su dani zadatci s ciljem samostalne provjere usvojenosti rješavanja računskih zadataka.
Mikroplastika u morskom okolišu Jadrana
Authors: Bule Kristina , Kučić Grgić Dajana , Ocelić Bulatović Vesna , Miloloža Martina , Radin Edi , Tolić Ana , Zadro Karla
Published: May 2020

Plastika se zbog svoje široke uporabe može naći u svim dijelovima okoliša, gdje štetno utječe na različite sastavnice okoliša, a toksični spojevi koje adsorbira prenose se kroz hranidbene lance te s vremenom dolaze do čovjeka. Odabrana istraživanja u ovom radu usredotočena su na karakterizaciju i kvantifikaciju mikroplastike pronađene u Jadranskom moru kao i na toksičnost mikroplastike. Istraživanja su pokazala da je najviše mikroplastike detektirano u području Sjevernog Jadrana. Provedena ispitivanja ekotoksičnosti mikroplastike primjenom testa s algama ukazuju na to da mikroplastika uzrokuje smanjenje brzine rasta i kretanja algi, obavljanje fotosinteze, fizičke deformacije te dolazi do smanjenja plodnosti i promjena u metaboličkim ciklusima.
HYPOXIA AND REPRODUCTIVE HEALTH: Oxygen and development of the human placenta
Authors: Burton Graham J , Cindrova-Davies Tereza , Yung Hong wa , Jauniaux Eric
Published: May 2020

Development of the human placenta takes place in contrasting oxygen concentrations at different stages of gestation, from ~20 mmHg during the first trimester rising to ~60 mmHg at the start of the second trimester before gradually declining to ~40 mmHg at term. In view of these changes, the early placenta has been described as ‘hypoxic’. However, placental metabolism is heavily glycolytic, supported by the rich supply of glucose from the endometrial glands, and there is no evidence of energy compromise. On the contrary, the trophoblast is highly proliferative, with the physiological low-oxygen environment promoting maintenance of stemness in progenitor populations. These conditions favour the formation of the cytotrophoblastic shell that encapsulates the conceptus and interfaces with the endometrium. Extravillous trophoblast cells on the outer surface of the shell undergo an epithelial-mesenchymal transition and acquire invasive potential. Experimental evidence suggests that these changes may be mediated by the higher oxygen concentration present within the placental bed. Interpreting in vitro data is often difficult, however, due to the use of non-physiological oxygen concentrations and trophoblast-like cell lines or explant models. Trophoblast is more vulnerable to hyperoxia or fluctuating levels of oxygen than to hypoxia, and some degree of placental oxidative stress likely occurs in all pregnancies towards term. In complications of pregnancy, such as early-onset pre-eclampsia, malperfusion generates high levels of oxidative stress, causing release of factors that precipitate the maternal syndrome. Further experiments are required using genuine trophoblast progenitor cells and physiological concentrations to fully elucidate the pathways by which oxygen regulates placental development.
SÁDABA GARAY, Javier: Memorias comillenses, Foca, Madrid, 2016, 125p; La religión al descubierto, Herder, Barcelona, 2016, 162p; ¿Van los perros al cielo?, Alfaguara, Madrid, 2016, 199p.
Authors: Del Olmo Ibáñez María
Published: May 2020

Reseña conjunta de los tres libros sobre religión publicados por Javier Sádaba en 2016
Teología platónica: a propósito de la Idea Suprema de Bien en la República
Authors: Acosta Jean Seas
Published: May 2020

La Idea Suprema de Bien constituye un problema investigativo que amerita reflexión, porque es posible determinar en Platón al primer teólogo de Occidente. Si la teología implica una reflexión racional sobre la divinidad, este es quien sienta la base de un acercamiento intelectual al dios. La teología que expresa el ateniense está matizada por la dimensión ontológica de la realidad, donde el dios puede ser comprendido como realidad-fundamento, donde es posible extraer consecuencias morales solamente a posteriori. Y esta concepción implica que su adecuada contemplación debe ser llevada a cabo por la vía de la religación, más que la religión. Palabras clave: Platón, República, Bien, Zubiri, Religación
Benefits and Risks of Visitor Restrictions for Hospitalized Children During the COVID Pandemic
Authors: Virani Alice K. , Puls Henry T. , Mitsos Rebecca , Longstaff Holly , Goldman Ran D. , Lantos John D.
Published: May 2020

To control the spread of severe acute respiratory syndrome coronavirus 2, the virus responsible for coronavirus disease 2019, many hospitals have strict visitor restriction policies. These policies often prohibit both parents from visiting at the same time or having grandparents or other family members visit at all. We discuss cases in which such policies created ethical dilemmas and possibly called for compassionate exceptions from the general rules.
Interrelationships between some vegetative components and fruit quality of Algerian date palm
Authors: Rekis A. , Laiadi Z.
Published: May 2020

Abstract. The date palm is a monocotyledon thermophilic desert plant, in Algeria grown more than 18 million trees. To have a better quality of dates for the most answered cultivars in Algeria, we can act with fertilization on the palm and these components of the leaflets and spines that affect dates quality. The three cultivars of date palms (Deglet nour-C1, Ghars-C2 and Mechdegla-C3) have been studied to estimate the relationship between leaflet and spine number and date quality. Five phenotypic traits were exploited and subjected to analysis of the principal components in ascending hierarchical classification. The results revealed that the cultivar Deglet nour scored the highest value for the parameters spine number (25) and weight of the date (8.63g), the cultivar Ghars also recorded the highest value for the parameters: number of leaflets (80) and length (4.35cm) and thickness (2.25cm) of the date. In all studied cultivars positive correlations between the length and width of the leaf – on the one side, and weight of the date – on the other, and between the width of leaf and width of the date were found.
A biszfoszfonátkezelés állcsontnekrózist előidéző kockázatának megítélése CBCT-felvételek alapján
Authors: Koppány Ferenc , Joób-Fancsaly Árpád , Németh Zsolt , Belik Andrea Alexandra , Vaszilkó Mihály , Varmuzsa Edvárd Márton , Csomó Krisztián Benedek
Published: May 2020

Absztrakt:

Bevezetés: A biszfoszfonátok által okozott
állcsontnekrózis (BRONJ) az életminőséget jelentősen befolyásoló megbetegedés,
mely mind általános, mind sebészeti vonatkozásaiban indokolja a korai diagnózis
felállítását, illetve a kialakulás kockázatának felmérését.
Célkitűzés: A BRONJ prognózisának becslése
nem megoldott, számos radiológiai lehetőség közül a legkedvezőbbnek a
fogászatban használatos képalkotó eljárások tűnnek, melyek közül a
legígéretesebb lehet a ’cone-beam computed tomography’ (CBCT). Az oralisan
alkalmazott biszfoszfonátterápia következtében kialakuló BRONJ kockázatbecslését
nem hangsúlyozzák a vizsgálatok, a nagyobb kockázatot jelentő intravénás
alkalmazásra fókuszálnak. Módszer: Méréseinket –
az eddig publikált vizsgálatokkal ellentétben – preoperatív CBCT-felvételeken
végeztük, ezáltal a kockázatbecslés lehetőségét közvetlenül vizsgáltuk.
Vizsgálatainkat CBCT-felvételek értékelésével végeztük; reprezentatív
területként a foramen mentale középvonalában elhelyezkedő frontális metszeteket
választottuk ki, és több ponton mértünk denzitást, a corticalis csontállomány
vastagságát, valamint a foramen mentale átmérőjét is megmértük. Az első
vizsgálati csoportban olyan osteoporosisos betegeket vizsgáltunk, akiknél oralis
biszfoszfonátterápiát követően alakult ki BRONJ. A második csoportban olyan
betegeket néztünk, akik osteoporosis miatt oralis biszfoszfonátterápiában
részesültek, és a szájsebészeti beavatkozást követően nem alakult ki BRONJ. A
kontrollcsoportban olyan betegek voltak, akik nem kaptak a BRONJ etiológiájában
szereplő gyógyszert. Eredmények: Eredményeink
alapján elmondható, hogy a preoperatív CBCT-felvételeket értékelve nem
tapasztalható jelentős különbség a BRONJ-elváltozástól szenvedők és az
egészségesek csontdenzitási értékei között.
Következtetés: Ezek alapján kijelenthető, hogy
a sugárterheléssel járó CBCT-felvétel az osteoporosis miatt oralis
biszfoszfonátot szedők esetében a BRONJ prognosztikai becslésére nem
alkalmazható. Mindez fontos ahhoz, hogy a prognózisbecsléshez a pácienst érő
sugárdózist ne emeljük szükségtelenül az ALARA (as low as reasonably
achievable)-elv értelmében. Orv Hetil. 2020; 161(21): 867–872.
A COVID–19-betegek, tünetmentes hordozók, illetve a betegségen már átesettek periodikus monitorizálási lehetősége IgM/IgG antitest alapú gyorstesztekkel az egészségügyi személyzet körében a SARS-CoV-2-járvány idején
Authors: Ragó Zsuzsanna , Szijjártó László , Duda Ernő , Bella Zsolt
Published: May 2020

Absztrakt:

Magyarország 2020. március 4-én jelentette az első COVID–19-fertőzésben szenvedő
beteget. Az új koronavírusnak (SARS-CoV-2) az egészségügyben dolgozók vannak
kitéve a legnagyobb mértékben, akik a jelenleg igazolt fertőzöttek 12%-át teszik
ki. Az esetek 80%-a enyhe, középsúlyos tünetekkel vagy akár tünetmentesen
zajlik. A vírus örökítőanyaga (egyszálú RNS) 30–40 napig mutatható ki RT-PCR
technikával a légutakból, a vizeletből, a vérből vett mintákból és – főleg
gyermekek esetében – a székletből. A szisztematikus tesztelés hiányában nincs
adatunk, hogy a magyarországi járvány kezdete óta vajon hány egészségügyi
dolgozó eshetett át a fertőzésen, akik maguk is kritikus fertőzőforrások
lehetnek mind az általuk ellátott betegek, mind családtagjaik számára. Fontos
lenne tudni keresztmetszeti és longitudinális vizsgálattal is, hogy milyen
közöttük a betegséget már átvészeltek, azaz a védettek, az akut fázisban lévők,
azaz a fertőzők, és a vírusnaivok, azaz a veszélyeztettek aránya. A
rendelkezésre álló laboratóriumi diagnosztikai módszerek közül az RT-PCR mellett
az újonnan elérhető, antitestalapú gyorstesztek jöhetnének szóba a kérdés
megválaszolására, amelyek gyorsak, könnyen kivitelezhetők, olcsók, és alkalmasak
lehetnek az egészségügyi dolgozók periodikus monitorizálására a SARS-CoV-2 által
okozott, még ismeretlen időtartamú járvány alatt. Orv Hetil. 2020; 161(21):
854–860.
Про існування деформацій овалоїдів
Authors: Подоусова Тетяна , Вашпанова Ніна
Published: May 2020

У даній роботі у тривимірному евклідовому просторі E3 розглядаються загальні нескінченно малі (н.м.) деформації вищих порядків однозв'язних поверхонь, які мають важливе значення при вивченні їх неперервних деформацій. Завдання знаходження векторів зсуву цих деформацій зводиться до дослідження і розв'язку системи n рівнянь (або основних рівнянь) загальних н. м. деформацій скінченого порядку n, які отримані відносно довільно обраної на поверхні системи координат. Показано, що для замкнутих поверхонь додатньої гаусової кривини математичною моделлю цього завдання в сполучено-ізотермічній системі координат буде система n неоднорідних рівнянь комплексного виду, яка у випадку овалоїда приводиться до системи n інтегральних рівнянь. Використовуючи тензорні методи, апарат теорії узагальнених аналітичних функцій і методи функціонального аналізу, доведено, що регулярний овалоїд в E3 «в цілому» допускає загальну н.м. деформацію скінченого порядку n, яка однозначно визначається заздалегідь заданими 3n функціями. Знайдений їх геометричний зміст: завдання їх рівносильно завданням значень варіацій орта нормалі і елемента площі до порядку n включно. Векторні поля деформації при цьому визначаються з точністю до постійних векторів. Встановлено, що овалоїд буде жорстким щодо загальних н.м. деформацій скінченого порядку n тоді і тільки тоді, коли всі значення варіацій орта нормалі і елемента площі до порядку n включно тотожно рівні нулю. В якості прикладу поверхні, яка підтверджує отриманий результат, розглянута сфера радіуса R. Вектори зміщень при цьому знайдені в явному вигляді.
Evaluation of the Biomass of Beetle Families in Different Districts of Volgograd Region
Authors: Brekhov Oleg
Published: May 2020

The biomass of two groups of beetles was assessed in Volgograd region.All areas under research were different in their environmental conditions. In Kumylzhensky district, biotopes of the mountain oak, in Novonikolaevsky – the floodplain of the Kaldair River, in Chernyshkovsky – sand sections, and in Kalachevsky – steppe sections of the BolshayaGolubaya river valleywere studied. During the study of herpetobiont beetles, 2497 trap-days were conducted, with the help of which 2465 copies of beetles from 20 families were caught. The biomass of all beetlescollected was 460.67 g and the average weight was 0.184 g/trap-day. Arid conditions increase the biomass of ground beetles due to the family of black teats and plate trees, the maximum biomass is in sandy soils. The base of the complex of ground beetles of the region are representatives of families of tenebrionidae and carabidae, under favorable conditions the predominant families can include scarabaeioidae, cerambycidae, silphidae, histeridae and curculionidae. 114 mowingswere carried out in grasslands and steppe areas to study hortebion beetles. As a result, about 4000 beetles from 29 families were collected. The total biomass was 28.572 g, with the average weight of 2.506 g/10 sacks. Arid conditions reduce the mass of herbal beetles due to more sparse vegetation, and as a result, species diversity and the number of beetles decrease. The base of the complex of horthobion beetles of the region are members of the family of curculionidae, scarabaeioidae, coccinellidae and chrysomelidae. Depending on the type of vegetation, locally, high biomass can have families of cerambycidae, elateridae, cantharidae, oedemeridae, malachidae.
Cartographic Methods of the Research of the Rural Settlement System in Volgograd Region
Authors: Khavanskaya Natalya , Alyaev Vladimir , Semenova Diana
Published: May 2020

The article presents the methodology of cartographic support of economic and geographical research of rural territories in Volgograd region. The methodological basis of the article is the theoretical foundations of classical economic geography and applied directions of geoinformation mapping. The authors consider the stages of the study, including: identification of mapped indicators; formation of an information base; compilation of thematic maps for each indicator; compilation of an integrated assessment card for a set of indicators. The following are proposed as the main mapped indicators: the number of rural population in 2010, % by 1969; density of the rural population in 2010, people / km2; grouping of rural settlements by population, people; grouping of rural settlements by extrapolation tendency; conditions of the temporary transport accessibility of Volgograd; conditions of the temporary transport accessibility of the district center; natural fertility of agricultural lands in bonitet points. When constructing thematic maps, methods for classifying numerical fields are used, based on the calculation of the standard deviation: for maps of population dynamics, population density, and soil quality of agricultural land. Isoline mapping is used in the construction of maps of temporary transport accessibility, where the main methods of mapping are isochrones. To conduct a comprehensive assessment of the favorable resource potential of rural areas, the method of applying thematic maps is used, i.e. overlay operations. The methodology proposed by the authors as a whole allows the formation of an information database that includes information on the dynamics of the rural population in Volgograd region for individual villages, individual rural settlements, the density of the rural population in rural settlements, the conditions of transport accessibility of rural settlements, and the natural fertility of agricultural land in rural settlements, on the differences in resource potential in rural settlements.
COVID-19: unidades de terapia intensiva, ventiladores mecânicos e perfis latentes de mortalidade associados à letalidade no Brasil
Authors: Moreira Rafael da Silveira
Published: May 2020

O acelerado aumento do número de casos de doença pelo novo coronavírus (COVID-19) exige que os países aumentem as vagas nas unidades de terapia intensiva (UTI). Doenças respiratórias, neoplasias, cardiopatias, hipertensão e diabetes aumentam sua letalidade. O estudo objetivou identificar tanto as regiões com as maiores taxas de mortalidade específica por essas doenças quanto as com maior escassez de UTI e ventiladores pulmonares. Foi realizado um estudo ecológico transversal, as unidades de análise foram as Regiões de Saúde no Brasil. A fonte de dados foi o Departamento de Informática do SUS - DATASUS (Cadastro Nacional de Estabelecimentos de Saúde - 2019, Sistemas de Informação de Mortalidade - 2017 e Projeções Populacionais - 2017). Foram calculadas as taxas por 100 mil habitantes de mortalidade específica para hipertensão, neoplasias, diabetes, doenças cardíacas e respiratórias, leitos de UTI total, leitos de UTI privados, leitos de UTI do Sistema Único de Saúde (SUS) e ventiladores do SUS. O perfil de mortalidade foi determinado pela análise de perfis latentes, e a análise de clusters dos leitos e ventiladores foi feita pelo método de varredura espacial. Mapas de Kernel foram construídos para a visualização dos dados. O nível de significância foi de 5%. Observou-se quatro perfis latentes de mortalidade. As regiões de saúde com as maiores médias na mortalidade estão localizadas em regiões cuja escassez de leitos de UTI e de ventiladores foi visualizada, especialmente, em partes das regiões Nordeste, Sudeste e Sul. A localização espacial das regiões com maior mortalidade e com escassez de leitos de UTI/ventiladores requer a atenção dos gestores e planejadores públicos, para o enfrentamento eficiente e equânime da epidemia no Brasil.
Vertical social distancing policy is ineffective to contain the COVID-19 pandemic
Authors: Duczmal Luiz Henrique , Almeida Alexandre Celestino Leite , Duczmal Denise Bulgarelli , Alves Claudia Regina Lindgren , Magalhães Flávia Costa Oliveira , Lima Max Sousa de , Silva Ivair Ramos , Takahashi Ricardo Hiroshi Caldeira
Published: May 2020

Abstract: Considering numerical simulations, this study shows that the so-called vertical social distancing health policy is ineffective to contain the COVID-19 pandemic. We present the SEIR-Net model, for a network of social group interactions, as a development of the classic mathematical model of SEIR epidemics (Susceptible-Exposed-Infected (symptomatic and asymptomatic)-Removed). In the SEIR-Net model, we can simulate social contacts between groups divided by age groups and analyze different strategies of social distancing. In the vertical distancing policy, only older people are distanced, whereas in the horizontal distancing policy all age groups adhere to social distancing. These two scenarios are compared to a control scenario in which no intervention is made to distance people. The vertical distancing scenario is almost as bad as the control, both in terms of people infected and in the acceleration of cases. On the other hand, horizontal distancing, if applied with the same intensity in all age groups, significantly reduces the total infected people “flattening the disease growth curve”. Our analysis considers the city of Belo Horizonte, Minas Gerais State, Brazil, but similar conclusions apply to other cities as well. Code implementation of the model in R-language is provided in the supplementary material.
Intergenerational financial transfers and physical health of old people in rural China: evidence from CHARLS data
Authors: Chen Guangyan , Si Wei , Qiu Lingling
Published: May 2020

ABSTRACT: With the reduction of intergenerational temporal transfers, financial transfers from adult offspring to their elderly parents are prevailing in rural China. Although much has been done, little is known about the association between the expansion of intergenerational transfers and rural old people’s physical health in China. The purpose of this paper was to examine the effect of intergenerational financial transfers on the elders’ physical health in rural China. Using data collected from China Health and Retirement Longitudinal Study (CHARLS), panel data fixed effect model and threshold model are employed to estimate the impact of intergenerational financial transfers on the old people’s physical health in rural areas. Results showed that; although, the intergenerational financial transfers have a positive effect on the old people’s physical health, no linear relationship exists between them. Intergenerational financial transfers are clearly less effective for low-income old people’s physical health than those of middle-income, while the effect on high-income old people’s health is the most insignificant. Studies concerning the effect of intergenerational financial transfers on the elders’ health in developing countries remain limited. Findings of this paper provided great insights into how intergenerational transfers, such as intergenerational financial transfers, may affect the well-beings of old residents in rural areas. Additionally, this study can offer inspiration to policy makers regarding what measures they should take to enhance rural old residents’ well-beings.
Application of product development tools in equipment design for a technology-based small business
Authors: Pierobom Felipe Mello , Andrade Jairo José de Oliveira
Published: May 2020

Abstract: The main objective of this paper is to use the techniques and methods of Product Process Development in the equipment development for a technology-based small business. Conceptual design concepts were generated and through the use of a morphological matrix the options of confection of the final conceptual prototype were verified. With the definition of the previous steps, the project team cataloged the main requirements and functions of the equipment and compared and evaluated them with a reference concept already used in the external environment of the company, verifying their priorities through the Mudge Method. Subsequently, the study of the needs of improvements in the main functions was done creating a final functional prototype for use in the work environment. The application of these techniques allowed quantifying the productivity of the product manufactured by equipment, comparing the situation before and after the process with the new equipment. In addition it was verified that when the process is carried out by the equipment developed there is a productivity improvement since this allowed to reduce the amount of losses; decrease production variability over time, since there is no operator wear and more results standardization.