bluuebunny/crossref_metadata_2025 huggingface dataset:
Electroencephalography (EEG)-Based Comfort Evaluation of Free-Form and Regular-Form Landscapes in Virtual Reality
Authors: Ren Hongguo , Zheng Ziming , Zhang Jing , Wang Qingqin , Wang Yujun
Published: January 2024

Urban landscape parks play a crucial role in providing recreational opportunities for citizens. Different types of landscapes offer varying levels of comfort experiences. However, the assessment of landscape comfort primarily relies on subjective evaluations and basic physiological measurements, which lack sufficient quantification of relevant data. This study employed electroencephalography (EEG) technology and subjective questionnaire evaluation methods. Participants observed two sets of landscape demonstration videos using virtual reality (VR) devices, and EEG alpha values and subjective evaluation scores were collected to assess the comfort levels of free-form landscape and regular-form landscape. Additionally, this study explored the correlation between landscape characteristics and physiological comfort. The analysis of the results showed that: 1. The average amplitude of EEG alpha waves recorded from 11 electrodes in the left temporal lobe and right parietal lobe of the participants was higher after they watched the free-form landscape demonstration. The increased alpha values suggest that free-form landscapes are more likely to induce physiological comfort in these specific brain regions. In contrast, regular-form landscape was found to induce higher alpha values at seven specific electrodes located in the occipital cortex, right temporal lobe, and central regions of the participants. In general, free-form landscape provided physiological comfort to a greater number of brain regions. 2. The two groups of landscapes exhibit distinct subjective cognitive differences in terms of their landscape characteristics. These differences, ranked in order of magnitude, include rhythmicity, sense of order, sense of security, and sense of dependence. 3. This study examined the α-waves of specific brain regions, including the right and left temporal lobe and occipital lobe, as well as subjective scoring. It discovered that the rhythmicity, degree of variation, degree of color, and sense of nature of a landscape impact the α-wave value of electrodes in different brain regions. Moreover, there exists a certain linear relationship between the four landscape features and the α-wave values in different regions of the brain. The results of this study provide some reference for the creation of a comfortable landscape design.
Main Nuclear Responses of the DEMO Tokamak with Different In-Vessel Component Configurations
Authors: Park Jin Hun , Pereslavtsev Pavel
Published: January 2024

Research and development of the DEMOnstration power plant (DEMO) breeder blanket (BB) has been performed in recent years based on a predefined DEMO tritium breeding ratio (TBR) requirement, which determines a loss of wall surface due to non-breeding in-vessel components (IVCs) which consume plasma-facing wall surface and do not contribute to the breeding of tritium. The integration of different IVCs, such as plasma limiters, neutral beam injectors, electron cyclotron launchers and diagnostic systems, requires cut-outs in the BB, resulting in a loss of the breeder blanket volume, TBR and power generation, respectively. The neutronic analyses presented here have the goal of providing an assessment of the TBR losses associated with each IVC. Previously performed studies on this topic were carried out with simplified, homogenized BB geometry models. To address the effect of the detailed heterogeneous structure of the BBs on the TBR losses due to the inclusion of the IVCs in the tokamak, a series of blanket geometry models were developed for integration in the latest DEMO base model. The assessment was performed for both types of BBs currently developed within the EUROfusion project, the helium-cooled pebble bed (HCPB) and water-cooled lead–lithium (WCLL) concepts, and for the water-cooled lead and ceramic breeder (WLCB) hybrid BB concept. The neutronic simulations were performed using the MCNP6.2 Monte Carlo code with the Joint Evaluated Fission and Fusion File (JEFF) 3.3 data library. For each BB concept, a 22.5° toroidal sector of the DEMO tokamak was developed to assess the TBR and nuclear power generation in the breeder blankets. For the geometry models with the breeder blanket space filled only with blankets without considering IVCs, the results of the TBR calculations were 1.173, 1.150 and 1.140 for the HCPB, WCLL and WLCB BB concepts, respectively. The TBR impact of all IVCs and the losses of the power generation were estimated as a superposition of the individual effects.
The Effects of Systemic Vitamin D Level on the Healing of Different Graft Materials: An Experimental Histological Study
Authors: Hacibektasoglu Mehmet Sefa , Balcioglu Huseyin Avni , Uyanikgil Yigit , Balcioglu Nilufer Bolukbasi
Published: January 2024

The aim of this study is to investigate the effects of serum vitamin D levels on the healing of different bone graft materials. Thirty-six male rats were divided into three groups and fed special feeds containing different amounts of vitamin D for 6 weeks before the surgical phase: the high serum vitamin D level group (group H) 10,000 iu/kg vitamin D3; the standard serum vitamin D level group (group C) 1000 iu/kg D3; and the low-level vitamin D group (group L) 100 iu/kg vitamin D3. Under general anesthesia, four defects with a diameter of 5 mm were created in the calvaria of the rats. The defects were augmented with autogenous grafts, allografts, xenografts, or left empty. The serum vitamin D level was measured before the surgery and before sacrifice. At the end of the 6th week, the subjects were sacrificed, and histological and histomorphometric analyses were performed. Study results show that in all graft types, as vitamin D levels increase, the number of new bone formations increases. There was no significant difference between the graft materials in terms of new bone formation criteria in group L. In group H and group C, the highest new bone formation was seen in the allograft group (1.48 ± 0.07, 0.66 ± 0.19, respectively). Prospective randomized clinical studies are required to evaluate the effect of vitamin D dose on the success of augmentation procedures in the clinic.
A Novel Method Using 3D Interest Points to Place Markers on a Large Object in Augmented Reality
Authors: Kim Su Young , Kim Yoon Sang
Published: January 2024

Multiple markers are generally used in augmented reality (AR) applications that require accurate registration, such as medical and industrial fields. In AR using these markers, there are two inevitable problems: (1) geometric shape discrepancies between a real object and a virtual object, and (2) the relative positions of the markers placed on the virtual object and markers placed on the real object are not consistent. However, studies on applying multiple markers to a large object are still insufficient. Additionally, most studies did not consider these inevitable problems because the markers were subjectively placed (hereafter conventional method). In consideration of these problems, this paper proposes a method for placing multiple markers to provide accurate registration on a large object. The proposed method divides a virtual object evenly and determines the positions of multiple markers automatically using 3D interest points within the divided areas. The proposed method was validated through a performance comparison with the conventional method of subjectively placing markers, and it was confirmed to have more accurate registration.
Wire and Cable Quality Traceability System Based on Industrial Internet of Things and Blockchain
Authors: Zhao Jintao , Sun Wenlei , Lu Cheng , Zhang Xuedong , Wang Lixin , Wang Dajiang
Published: January 2024

Wire and cable are important industrial products involving the national economy and people’s livelihood, which are hailed as the “blood vessel” and “nerve” of the national economy, providing the basic guarantee for the normal operation of modern economy and society. The data traceability of their production and circulation process is a key factor in ensuring their quality and safety management. We aim to solve the problems of unsafe data transmission, weak quality control, and information islands in the process of wire and cable quality traceability in order to improve the production management efficiency of wire and cable manufacturing enterprises and to reduce the cost of consumer quality traceability of wire and cable products. We analyzed the technical characteristics and advantages of Industrial Internet of Things (IIoT) identity resolution and the blockchain. Key technologies are introduced, a traceability method that integrates the two is proposed, and a quality traceability framework based on the IIoT identity resolution system and blockchain technology is constructed. By analyzing the quality information composition of the wire and cable supply chain, a new quality traceability model based on the wire and cable supply chain is established. Finally, through the verification of the developed quality traceability system, the quality traceability function and quality information of each production link of wire and cable are successfully realized. This paper fills a gap in the field of cable product quality traceability using the combination of IIoT and blockchain technology. According to this model, it also has some potential for the traceability of other industrial products.
Implementation of Quality Tools in Mechanical Engineering Piece Production
Authors: Markulik Štefan , Šolc Marek , Fiľo Milan
Published: January 2024

The world is undergoing dynamic changes. For businesses, it brings positives, but also negatives. The positive is the global market for business. The downside of the global market is the increasing competitive pressure. Large enterprises with serial production who are setting production for a longer period ahead are not so noticeable. Small companies are the most vulnerable. There are various tools or overall approaches to business management that allow them to increase work efficiency or production productivity or eliminate waste. In recent years, one can see an increase in the popularity of Lean or Six Sigma. Their contribution to businesses cannot be disputed. Most of the tools and approaches to support business management are oriented or based on the conditions of serial production. Small businesses with piece production are at a disadvantage here. It was this fact that motivated us to focus on piece production and to find space for the implementation of supporting tools that could be helpful. Our research has shown that there are tools that can be applied in the conditions of piece production. The application of the identified tools proved that the results achieved in reducing production times or increasing productivity are unmistakable.
Pilot Study on the Biomechanical Quantification of Effective Offensive Range and Ball Speed Enhancement of the Diving Header in Soccer: Insights for Skill Advancement and Application Strategy
Authors: Shan Gongbing , Liu Yufeng , Gorges Tom , Zhang Xiang , Witte Kerstin
Published: January 2024

This pioneering study presents an in-depth biomechanical examinations of soccer’s diving header, aiming to quantify its impact on ball speed enhancement (BSE) and effective offensive range (EOR). Despite the diving header’s widespread acclaim and historical significance, there remains a dearth of scientific scrutiny into its biomechanical intricacies. Employing an innovative research design featuring a static hanging ball at varied offensive distances and heights, this study replicates diverse header scenarios. The results of 3D motion quantification have shown that a physically excellent player (identified through the maximal standing long jump test) could reach an EOR around 2.64 times his body height. Furthermore, this study unveils that proficient players could attain BSE surpassing 9 m/s, signifying the diving header’s heightened efficacy compared to traditional heading techniques, which could only result in 4.5 m/s. Correlation analyses unveil noteworthy relationships, highlighting the pivotal role of head speed at impact and the influence of minimizing speed drop and temporal disparities for amplified effectiveness. Considerations for optimizing diving header execution are introduced, emphasizing the necessity for targeted training programs. Despite acknowledged limitations inherent to its pilot nature, this exploration furnishes foundational knowledge to guide subsequent research and practical applications, providing valuable insights into soccer training and skill development through a biomechanical lens.
Unraveling a Histopathological Needle-in-Haystack Problem: Exploring the Challenges of Detecting Tumor Budding in Colorectal Carcinoma Histology
Authors: Rusche Daniel , Englert Nils , Runz Marlen , Hetjens Svetlana , Langner Cord , Gaiser Timo , Weis Cleo-Aron
Published: January 2024

Background: In this study focusing on colorectal carcinoma (CRC), we address the imperative task of predicting post-surgery treatment needs by identifying crucial tumor features within whole slide images of solid tumors, analogous to locating a needle in a histological haystack. We evaluate two approaches to address this challenge using a small CRC dataset. Methods: First, we explore a conventional tile-level training approach, testing various data augmentation methods to mitigate the memorization effect in a noisy label setting. Second, we examine a multi-instance learning (MIL) approach at the case level, adapting data augmentation techniques to prevent over-fitting in the limited data set context. Results: The tile-level approach proves ineffective due to the limited number of informative image tiles per case. Conversely, the MIL approach demonstrates success for the small dataset when coupled with post-feature vector creation data augmentation techniques. In this setting, the MIL model accurately predicts nodal status corresponding to expert-based budding scores for these cases. Conclusions: This study incorporates data augmentation techniques into a MIL approach, highlighting the effectiveness of the MIL method in detecting predictive factors such as tumor budding, despite the constraints of a limited dataset size.
A Study on Developing a Model for Predicting the Compression Index of the South Coast Clay of Korea Using Statistical Analysis and Machine Learning Techniques
Authors: Lee Sungyeol , Kang Jaemo , Kim Jinyoung , Baek Wonjin , Yoon Hyeonjun
Published: January 2024

As large cities are continually being developed around coastal areas, structural damage due to the consolidation settlement of soft ground is becoming more of a problem. Estimating consolidation settlement requires calculating an accurate compressive index through consolidation tests. However, these tests are time-consuming, and there is a risk of the test results becoming compromised while preparing and testing the specimens. Therefore, predicting the compression index based on the results of relatively simple physical property tests enables more reliable and accurate predictions of consolidation settlement by calculating the compression index at multiple points. In this context, this study collected geotechnical data from the soft ground of Korea’s south coast. The collected data were used to construct a dataset for developing a compression index prediction model, and significant influencing factors were identified through Pearson correlation analysis. Simple and multiple linear regression analysis was performed using these factors to derive regression equations, and compression index prediction models were developed by applying machine learning algorithms. The results of deriving the significance of the influencing factors from the developed compression index prediction model showed that natural water content was the most significant factor in predicting the compression index. By collecting a significant amount of high-quality data and using the compression index prediction model and the model construction process proposed in this study, more accurate predictions of the compressive index will be possible in the future.
Distinctive Culture Expressions of Enterobacteria Interfering with Isolation of Salmonella spp. during the Application of the Recommended ISO 6579-1:2017
Authors: Evangelopoulou Grammato , Burriel Angeliki R. , Solomakos Nikolaos
Published: January 2024

The objective of the present report is the dissemination of information acquired during the application of ISO 6579-1:2017 for the isolation of Salmonella spp. from swine samples. ISO 6579-1:2017 is the protocol officially recommended by the EU for the isolation of Salmonella spp., aiming for the harmonization of effective control of Salmonella infection in food-producing animals. Successful control of animal salmonellosis is highly dependent on the sensitivity and reliability of the biochemical methods used to detect the presence of the pathogen in various stages of food production. Application of ISO 6579-1:2017 resulted in the isolation of twelve Salmonella spp. and eighteen other members of the family of Enterobacteriaceae biochemically and other bacteria antigenically resembling salmonellae. An evaluation of the culture media was conducted, including xylose-lysine-desoxycholate agar (XLD), Salmonella–Shigella Agar (SS), Brilliant Green Agar (BGA), Salmonella Chromogenic Agar (SCA), Triple Sugar Iron (TSI), and modified semi-solid Rappaport–Vassiliadis (MSRV) agar. The evaluation showed that these culture-selective media differed significantly in their performance for the isolation of Salmonella from swine samples. It was concluded that the presence of atypical Salmonella strains negatively affects the prevalence of Salmonella, thus affecting the identification of carrier pigs and eventually affecting the efficiency of control programs. Thus, doubtful results require additional biochemical testing to confirm the accuracy of such universally recommended isolation methods.
Quantitative Analysis of the Complex Time Evolution of a Camphor Boat
Authors: Roliński Tomasz , Kitahata Hiroyuki , Koyano Yuki , Górecki Jerzy
Published: January 2024

The motion of a camphor boat on the water’s surface is a long-studied example of the direct transformation of chemical energy into a mechanical one. Recent experimental papers have reported a complex character of boat motion depending on the location of the camphor source. If the source is close to the stern, the boat moves at a constant speed. When it is shifted towards the boat center, oscillations of speed are observed. When the source is close to the boat center, pulses of speed followed by oscillations appear. Here, we focus on numerical simulations of camphor boat motion. We discuss approximations that allow us to reduce the numerical complexity of the problem and formulate a model in which the equation for boat velocity is coupled with a one-dimensional reaction–diffusion equation for camphor surface concentration. We scanned the phase space of model parameters and found the values that give qualitative agreement with the experiments. The model predicts all types of boat motion (continuous, oscillating, and pulsating) observed in experiments. Moreover, the model with selected parameter values shows that for specific locations of the camphor source, a spike in speed is followed by transient oscillations, which are an inherent part of speed relaxation.
The Effect of Connection Ductility on Composite Steel–Concrete Bridges
Authors: Mohammadi Dehnavi Mohammad Mahdi , De Angelis Alessandra , Pecce Maria Rosaria
Published: January 2024

Connection behavior significantly influences the design efficiency of steel–concrete composite bridges. This study investigates the impact of shear connectors, specifically headed stud connectors, on the structural response of symmetric and skewed composite steel–concrete bridges. Utilizing bilinear or trilinear slip–shear strength laws for studs, in line with the existing literature and code provisions, a finite element (FE) model is developed. This FE model is applied to a case study for composite deck analysis, incorporating variations in connection strength and ductility for nonlinear analyses. The study assesses ductility demands in connections for symmetric and skewed bridges of varying lengths and angles, considering both ductile and elastic designs. Results emphasize the importance of stud capacity, ductility, and strength on the overall bridge response, analyzing slip and shear trends at the interface. Skewed bridges, crucial for non-orthogonal crossings of roads, are integral to modern transportation infrastructure. However, skewness angles exceeding 20° can result in undesirable effects on stresses in the deck due to vertical loads. The results indicate that shear distribution in studs changes significantly as the skew angle increases, contributing valuable insights into optimizing bridge design. Thus, this research provides a comprehensive analysis of principles, design methodologies, and practical applications for both symmetric and skewed steel–concrete composite bridges, considering various parameters.
Synthesis of Porous Carbon Nanomaterials from Vietnamese Coal: Fabrication and Energy Storage Investigations
Authors: Do Tra Huong , Nguyen Van Tu , Nguyen Thi Nga , Ha Xuan Linh , Nguyen Quoc Dung , Tran Thi Kim Ngan
Published: January 2024

The choice of precursor and simple synthesis techniques have decisive roles in the viable production and commercialization of carbon products. The intense demand for developing high-purity carbon nanomaterials through inexpensive techniques has promoted the usage of fossil derivatives as a feasible source of carbon. In this study, Vietnamese-coal-derived porous carbon (PC) was used to fabricate coal-derived porous carbon nanomaterials (CDPCs) using the modified Hummers method. The resulting porous carbon nanomaterials achieved a nanoscale structure with an average pore size ranging from 3 to 10 nm. The findings indicate that CDPC exhibits well-developed micropores and mesopores. The presence of macropores and mesopores not only facilitates the complete immersion of the material in the electrolyte but also effectively shortens the ion diffusion pathways. CDPC boasts a high carbon content, constituting 80.88% by weight. Electrochemical impedance spectroscopy (EIS) Nyquist plot of electrodes made from CDPC showed good conductivity value with low charge-transfer resistance. This electrode worked well and stably with capacitance retention of 74.7% after 1000 cycles. The CDPC specific capacitance reached 236 F/g under a current density of 0.1 A using the constant current discharge method and then decreased as the current density increased. Based on the results of the electrochemical properties of the materials, the energy storage capacity of the CDPC material was good and stable. This investigation presents an eco-friendly methodology for the judicious utilization of coal in energy storage applications, specifically as electrodes for supercapacitors and anodes for Li-ion batteries.
Nutritional Value and Microbiological Aspects of Dried Yellow Mealworm (Tenebrio molitor L.) Larvae Pretreated with a Pulsed Electric Field
Authors: Bogusz Radosław , Pobiega Katarzyna , Kowalczewski Przemysław Łukasz , Onopiuk Anna , Szulc Karolina , Wiktor Artur , Rybak Katarzyna , Nowacka Małgorzata
Published: January 2024

Complete protein, which includes all the essential amino acids, and bioactive compounds needed in human nutrition, can be found in edible insects. Bioactive compounds play a crucial role in protecting cells from the damage caused by free radicals. Therefore, in this study, fat extraction yield, protein content, amino acid profile, total polyphenol content, antioxidant properties, crustacean and mollusk content, and microbiological quality have been assessed to evaluate the influence of the drying method and pulsed electric field (PEF) pretreatment. To this end, the sample was processed by the PEF at varied specific energy intakes (5, 20, and 40 kJ/kg) and dried by means of two methods: convective (CD) and infrared-convective (IR-CD). A comparable protein content (47.5–48.7 g/100 g d.m.) was determined for most of the samples tested. A significantly higher lysine and methionine content was detected in the CD insects, especially for samples treated by the PEF at 40 kJ/kg. The IR-CD samples exhibited a significantly higher content of polyphenols as compared to those obtained by means of the CD method, whereas the PEF apparently had a significant impact to the extent of increasing their content. Taking into account allergenicity, the crustacean content was approximately 10 times higher than the mollusk content. The study has shown that the PEF treatment prior to infrared-convective drying resulted in the assurance of the microbiological quality of dried insects for food use. Furthermore, a dose of the PEF at 20 and 40 kJ/kg demonstrated the antimicrobial effect. The results have proven that, in this case, a high temperature during the CD method did not cause the undesirable changes that had been expected. Therefore, PEF-assisted convective drying may conceivably be considered to obtain highly nutritionally valuable insects; however, it is crucial to utilize appropriate parameters in the course of the PEF processing.
Experimental Light Rail Traffic Noise Assessment in a Metropolitan Area
Authors: Lázaro João , Costa Pedro Alves , Godinho Luís
Published: January 2024

The growth in the utilization and development of rail transport within urban networks is crucial for transitioning towards a more sustainable form of mobility. However, challenges related to discomfort and noise pollution arising from rail traffic must be addressed and mitigated to foster a harmonious coexistence between residents and trains. This study focuses on analyzing an experimental campaign conducted on the surface metropolitan network of Porto to study and identify the frequency content and pressure levels associated with light rail traffic. The presented experimental campaign holds significant relevance as it comprises various and distinct circulation conditions within the railway network, enabling a comprehensive characterization of railway noise. The collected data indicates a noticeable increase in sound pressure levels as the speed of circulation rises, particularly emphasizing the 1/3 octave band centered around 1000 Hz. The choice of tracks with components having a limited capacity for absorbing acoustic energy leads to a significant rise in noise levels compared to track solutions with elements exhibiting excellent acoustic energy absorption. Furthermore, the study highlights a substantial increase in noise levels (10 dBA) associated with small radius curves, even at low speeds. These findings underscore the importance of considering the track characteristics and geometric features in noise assessment within rail networks. Therefore, the insights gained from this experimental campaign contribute significantly to the understanding and comprehensive characterization of railway noise under diverse circulation conditions within the railway network.
Role of Bacteria-Derived Exopolysaccharides in Inflammatory Bowel Disease with a Special Focus on Cyanobacterial Exopolysaccharides
Authors: Manoharan Devaprakash , Natesan Sivakumar , Billamboz Muriel , Jawhara Samir
Published: January 2024

Instances of inflammatory bowel disease (IBD), a chronic inflammatory condition of the gastrointestinal tract, are rapidly increasing in western and newly industrialized countries. Exopolysaccharides (EPSs) are one of the strategies to enhance the gut microbiota and modulate the immune-inflammatory response deregulation in IBD patients. EPSs are produced by commensal bacteria such as Lactobacillus and Bifidobacterium. Additionally, Cyanobacteria species are promising sources of novel EPS and have potential pharmaceutical and therapeutic applications. The presence of uronic acids and sulphate groups in Cyanobacterial EPSs is an important factor that gives EPSs an anionic charge that is not seen in other prokaryotic species. This feature may impact their physico-chemical characteristics and biological properties. Additionally, Cyanobacterial EPSs have a wide range of biotechnological applications that include use as thickeners, stabilizers, and gelling agents in the food and pharmaceutical sectors. The present review focuses on the role of EPSs in IBD, with a special focus on EPSs derived from Cyanobacteria. This review also covers the biological properties of Cyanobacterial EPS in immuno-inflammatory responses and against pathogens as well as its role in biotechnological applications. Overall, Cyanobacterial EPSs have therapeutic potential against IBD due to their anti-inflammatory and immunoregulatory properties that can reduce inflammation and regulate the immune response and restore the gut microbiota of patients.
Connecting Global Modes of Variability to Climate in High Mountain Asia
Authors: Massoud Elias C. , Lim Young-Kwon , Andrews Lauren C. , Girotto Manuela
Published: January 2024

Oscillations in global modes of variability (MoVs) form global teleconnections that affect regional climate variability and modify the potential for severe and damaging weather conditions. Understanding the link between certain MoVs and regional climate can improve the ability to more accurately predict environmental conditions that impact human life and health. In this study, we explore the connection between different MoVs, including the Arctic oscillation (AO), Eurasian teleconnection, Indian Ocean dipole (IOD), North Atlantic oscillation (NAO), and El Niño southern oscillation (Nino34), with winter and summer climates in the High Mountain Asia (HMA) region, including geopotential height at 250 hPa (z250), 2 m air temperature (T2M), total precipitation (PRECTOT), and fractional snow cover area (fSCA). Relationships are explored for the same monthly period between the MoVs and the climate variables, and a lagged correlation analysis is used to investigate whether any relationship exists at different time lags. We find that T2M has a negative correlation with the Eurasian teleconnection in the Inner Tibetan Plateau and central China in both winter and summer and a positive correlation in western China in summer. PRECTOT has a positive correlation with all MoVs in most regions in winter, especially with the IOD, and a negative correlation in summer, especially with the Eurasian teleconnection. Snow cover in winter is positively correlated with most indices throughout many regions in HMA, likely due to wintertime precipitation also being positively correlated with most indices. Generally, the AO and NAO show similar correlation patterns with all climate variables, especially in the winter, possibly due to their oscillations being so similar. Furthermore, the AO and NAO are shown to be less significant in explaining the variation in HMA climate compared to other MoVs such as the Eurasian teleconnection. Overall, our results identify different time windows and specific regions within HMA that exhibit high correlations between climate and MoVs, which might offer additional predictability of the MoVs as well as of climate and weather patterns in HMA and throughout the globe.
Monitoring of Thermal Runaway in Commercial Prismatic High-Energy Lithium-Ion Battery Cells via Internal Temperature Sensing
Authors: Kisseler Niklas , Hoheisel Fabian , Offermanns Christian , Frieges Moritz , Heimes Heiner , Kampker Achim
Published: January 2024

The temperature of a lithium-ion battery is a crucial parameter for understanding the internal processes during various operating and failure scenarios, including thermal runaway. However, the internal temperature is comparatively higher than the surface temperature. This particularly affects cells with a large cross-section, which is due to heat development within the cell and lower heat dissipation due to a poorer ratio of volume to surface area. This paper presents an approach that enables real-time monitoring of the behavior of a commercial prismatic high-energy battery cell (NMC811/C, 95 Ah, Contemporary Amperex Technology Co., Limited (Ningde, China)) in the event of thermal runaway induced by overcharging. The internal cell temperature is investigated by the subsequent integration of two hard sensors between the two jelly rolls and additional sensors on the surface of the aluminum housing of the battery cell. The sensor’s signals show a significant increase in the temperature gradient between the temperature in the core of the cell and the cell casing surface until the onset of venting and thermal runaway of the battery. The data enable a detailed investigation of the behavior of the battery cell and the comparatively earlier detection of the point of no return in the event of thermal runaway.
AI-Based User Empowerment for Empirical Social Research
Authors: Reis Thoralf , Dumberger Lukas , Bruchhaus Sebastian , Krause Thomas , Schreyer Verena , Bornschlegl Marco X. , Hemmje Matthias L.
Published: January 2024

Manual labeling and categorization are extremely time-consuming and, thus, costly. AI and ML-supported information systems can bridge this gap and support labor-intensive digital activities. Since it requires categorization, coding-based analysis, such as qualitative content analysis, reaches its limits with large amounts of data and could benefit from AI and ML-based support. Empirical social research, its application domain, benefits from Big Data’s ability to create more extensive human behavior and development models. A range of applications are available for statistical analysis to serve this purpose. This paper aims to implement an information system that supports researchers in empirical social research in performing AI-supported qualitative content analysis. AI2VIS4BigData is a reference model that standardizes use cases and artifacts for Big Data information systems that integrate AI and ML for user empowerment. Thus, this work’s concepts and implementations try to achieve an AI2VIS4BigData-compliant information system that supports social researchers in categorizing text data and creating insightful dashboards. Thereby, the text categorization is based on an existing ML component. Furthermore, it presents two evaluations that were conducted for these concepts and implementations: a qualitative cognitive walkthrough assessing the system’s usability and a quantitative user study with 18 participants revealed that though the users perceive AI support as more efficient, they need more time to reflect on the recommendations. The research revealed that AI support increased the correctness of the users’ categorizations but also slowed down their decision-making. The assumption that this is due to the UI design and additional information for processing requires follow-up research.
Effects of Light Color on the Growth, Feeding, Digestion, and Antioxidant Enzymes of Tripneustes gratilla (Linnaeus, 1758)
Authors: Zhao Xinye , Guo Yu , Li Jiayang , Ma Zhenhua , Yu Gang , Qin Chuanxin
Published: January 2024

To study the effects of light color on sea urchin (Tripneustes gratilla), blue light (B, λ450nm), yellow light (Y, λ585–590nm), red light (R, λ640nm), green light (G, λ510nm), white light (W, λ400–780nm), and darkness (H) groups were established in a recirculating seawater aquaculture system. Six different LED light color treatment groups with a photoperiod of 12 L:12 D were tested for 30 days to investigate the effects of different light colors on the feeding, growth, and enzyme activities of T. gratilla (142.45 ± 4.36 g). We found that using different LED light colors caused significantly different impacts on the feeding, growth, and enzyme activity of T. gratilla. Notably, the sea urchins in group B exhibited better growth, with a weight gain rate of 39.26%, while those in group R demonstrated poorer growth, with a weight gain rate of only 26%. The feeding status differed significantly (p < 0.05) between groups B and R, with group B consuming the highest daily intake (6.03 ± 1.69 g) and group R consuming the lowest (4.54 ± 1.26 g). Throughout the three phases, there was no significant change in the viability of the α-amylase (p > 0.05). Conversely, the pepsin viability significantly increased (p < 0.05) in group B. The lipase viability consistently remained at the lowest level, with no notable differences between group W and group B. In group R, both the α-amylase and pepsin viabilities remained lower, whereas the lipase viability was noticeably greater in each phase than in group B (p < 0.05). Among the antioxidant enzymes, group R exhibited a trend of initial increase followed by decreases in catalase, superoxide dismutase, and glutathione peroxidase activities, particularly during the third stage (15–30 days), during which a significant decrease in antioxidant enzyme activity was observed (p < 0.05). Taken together, these findings suggest that blue light positively affects the growth, feeding, digestion, and antioxidant capacity of T. gratilla in comparison with those in other light environments, whereas red light had an inhibitory effect. Furthermore, T. gratilla is a benthic organism that lives on shallow sandy sea beds. Thus, as short wavelengths of blue and green light are more widely distributed on the seafloor, and long wavelengths of red light are more severely attenuated on the seafloor, shorter wavelengths of light promote the growth of bait organisms of sea urchins, which provide better habitats for T. gratilla.
Zinc-Dependent Histone Deacetylases in Lung Endothelial Pathobiology
Authors: Patil Rahul S. , Maloney McKenzie E. , Lucas Rudolf , Fulton David J. R. , Patel Vijay , Bagi Zsolt , Kovacs-Kasa Anita , Kovacs Laszlo , Su Yunchao , Verin Alexander D.
Published: January 2024

A monolayer of endothelial cells (ECs) lines the lumen of blood vessels and, as such, provides a semi-selective barrier between the blood and the interstitial space. Compromise of the lung EC barrier due to inflammatory or toxic events may result in pulmonary edema, which is a cardinal feature of acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS). The EC functions are controlled, at least in part, via epigenetic mechanisms mediated by histone deacetylases (HDACs). Zinc-dependent HDACs represent the largest group of HDACs and are activated by Zn2+. Members of this HDAC group are involved in epigenetic regulation primarily by modifying the structure of chromatin upon removal of acetyl groups from histones. In addition, they can deacetylate many non-histone histone proteins, including those located in extranuclear compartments. Recently, the therapeutic potential of inhibiting zinc-dependent HDACs for EC barrier preservation has gained momentum. However, the role of specific HDAC subtypes in EC barrier regulation remains largely unknown. This review aims to provide an update on the role of zinc-dependent HDACs in endothelial dysfunction and its related diseases. We will broadly focus on biological contributions, signaling pathways and transcriptional roles of HDACs in endothelial pathobiology associated mainly with lung diseases, and we will discuss the potential of their inhibitors for lung injury prevention.
Prophylactic Oral Application of Activated Charcoal Mitigates Acute Campylobacteriosis in Human Gut Microbiota-Associated IL-10−/− Mice
Authors: Heimesaat Markus M. , Schabbel Niklas , Langfeld Luis Q. , Shayya Nizar W. , Mousavi Soraya , Bereswill Stefan
Published: January 2024

The incidence of human Campylobacter jejuni infections is increasing worldwide. It is highly desirable to prevent campylobacteriosis in individuals at risk for severe disease with antibiotics-independent non-toxic compounds. Activated charcoal (AC) has long been used as an anti-diarrheal remedy. Here, we tested the disease-mitigating effects of oral AC versus placebo in human gut microbiota-associated (hma) IL-10−/− mice starting a week prior to C. jejuni infection. On day 6 post-infection, the gastrointestinal C. jejuni loads were comparable in both infected cohorts, whereas campylobacteriosis symptoms such as wasting and bloody diarrhea were mitigated upon AC prophylaxis. Furthermore, AC application resulted in less pronounced C. jejuni-induced colonic epithelial cell apoptosis and in dampened innate and adaptive immune cell responses in the colon that were accompanied by basal concentrations of pro-inflammatory mediators including IL-6, TNF-α, IFN-γ, and nitric oxide measured in colonic explants from AC treated mice on day 6 post-infection. Furthermore, C. jejuni infection resulted in distinct fecal microbiota shift towards higher enterobacterial numbers and lower loads of obligate anaerobic species in hma mice that were AC-independent. In conclusion, our pre-clinical placebo-controlled intervention study provides evidence that prophylactic oral AC application mitigates acute murine campylobacteriosis.
Regulated Cell Death in Endometriosis
Authors: Huang Erqing , Wang Xiaoli , Chen Lijuan
Published: January 2024

Regulated cell death (RCD) represents a distinct mode of cell demise, differing from accidental cell death (ACD), characterized by specific signaling cascades orchestrated by diverse biomolecules. The regular process of cell death plays a crucial role in upholding internal homeostasis, acting as a safeguard against biological or chemical damage. Nonetheless, specific programmed cell deaths have the potential to activate an immune–inflammatory response, potentially contributing to diseases by enlisting immune cells and releasing pro-inflammatory factors. Endometriosis, a prevalent gynecological ailment, remains incompletely understood despite substantial progress in unraveling associated signaling pathways. Its complexity is intricately tied to the dysregulation of inflammatory immune responses, with various RCD processes such as apoptosis, autophagic cell death, pyroptosis, and ferroptosis implicated in its development. Notably, limited research explores the association between endometriosis and specific RCD pathways like pyroptosis and cuproptosis. The exploration of regulated cell death in the context of endometriosis holds tremendous potential for further advancements. This article thoroughly reviews the molecular mechanisms governed by regulated cell death and their implications for endometriosis. A comprehensive understanding of the regulated cell death mechanism in endometriosis has the potential to catalyze the development of promising therapeutic strategies and chart the course for future research directions in the field.
Stereoelectroencephalography-Guided Radiofrequency Thermocoagulation: Diagnostic and Therapeutic Implications
Authors: Castellano James F. , Singla Shobhit , Barot Niravkumar , Aronson Joshua P.
Published: January 2024

Despite recent medical therapeutic advances, approximately one third of patients do not attain seizure freedom with medications. This drug-resistant epilepsy population suffers from heightened morbidity and mortality. In appropriate patients, resective epilepsy surgery is far superior to continued medical therapy. Despite this efficacy, there remain drawbacks to traditional epilepsy surgery, such as the morbidity of open neurosurgical procedures as well as neuropsychological adverse effects. SEEG-guided Radiofrequency Thermocoagulation (SgRFTC) is a minimally invasive, electrophysiology-guided intervention with both diagnostic and therapeutic implications for drug-resistant epilepsy that offers a convenient adjunct or alternative to ablative and resective approaches. We review the international experience with this procedure, including methodologies, diagnostic benefit, therapeutic benefit, and safety considerations. We propose a framework in which SgRFTC may be incorporated into intracranial EEG evaluations alongside passive recording. Lastly, we discuss the potential role of SgRFTC in both delineating and reorganizing epilepsy networks.
Your Pain Pleases Others: The Influence of Social Interaction Patterns and Group Identity on Schadenfreude
Authors: Sun Binghai , Huang Tongyin , Wu Ying , Fan Liting
Published: January 2024

Schadenfreude is a joyful emotional response to the misfortune of others. Individuals’ schadenfreude over the misfortunes of ingroup and outgroup members may vary depending on how groups interact. Accordingly, this study examines the effects of different social interaction patterns and group identity on schadenfreude and their mechanisms. The study participants were Chinese college students. Study 1 (n = 83) investigated whether there are differences in individuals’ schadenfreude towards ingroup and outgroup members under two different patterns of social interaction: cooperation and competition. On the basis of this study, Study 2 (n = 73) focused on the mechanisms underlying the influence of individuals’ Schadenfreude on ingroup and outgroup members in competitive situations, and the mediating role of disgust. It was found that there was an interaction between group identity and social interaction patterns, with people showing more schadenfreude over the misfortunes of outgroup members than ingroup members, and competitive situations increasing disgust and schadenfreude over outgroup members. However, no differences were found in individuals’ schadenfreude towards ingroup and outgroup members in cooperative situations. This is instructive in terms of real-life intergroup relations as well as patterns of social interaction. This proves that cooperation and group contact is a way to reduce schadenfreude.
Buffeting Characteristics of a Long-Span Cable-Stayed Bridge Crossing a Deep Canyon during Erection: Response Evaluation and Vibration Control
Authors: Zhang Yichi , Zhang Tianyi , Su Yi
Published: January 2024

The stiffness of a long-span cable-stayed bridge under construction may be much lower than that observed in service, making it more susceptible to wind effects, especially for a bridge designed using high piers crossing a deep canyon. To study the buffeting characteristics of such cable-stayed bridges under construction, a long-span cable-stayed bridge (the main span is 575 m) is taken as the engineering background. In this study, the buffeting responses and vibration countermeasures at three different construction states were systematically studied using time-domain analysis. It was found that the buffeting response enlarges with an increase in the wind attack angle. The RMS values of the vertical buffeting of the bridge deck end are relatively greater at the maximum double cantilever construction state and maximum single cantilever state. At maximum double cantilever construction state, the traditional wind-resistant cable connecting the bridge deck end to the bridge pile cap significantly reduces the vertical buffeting response, while the suppression effect on lateral and torsional buffeting is limited. When the bridge deck nears completion, wind-resistant cables installed at both cantilever ending in the ‘soft connection’ method would effectively suppress the vertical, lateral, and torsional buffeting. The suppression effect of cross-arranged wind-resistant cables is superior to that of the parallel arrangement. It is recommended that a reasonable wind-resistant cable layout scheme according to different construction conditions is selected.