bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Glucose-Lowering Medications on Health-Related Quality of Life in the Glycemia Reduction Approaches in Diabetes (GRADE) Study: A Comparative Effectiveness Randomized Clinical Trial
Authors: L. Cherrington Andrea , T. Tripputi Mark , Younes Naji , H. Herman William , Katona Aimee , J. Groessl Erik , Craig Jacqueline , S. Gonzalez Jeffrey , Garg Rajesh , Casula Sabina , Kuo Shihchen , J. Florez Hermes
Published: January 2024

Objective: Diabetes is associated with reduced health-related quality of life (HRQoL). Information on the relationship between HRQoL and glucose-lowering medications in recently diagnosed type 2 diabetes (T2D) is limited. We assessed changes in HRQoL in participants with T2D receiving metformin plus one of four glucose-lowering medications in the GRADE study.

Research Design and Methods: 5047 participants with baseline mean age of 57 years, <10 years T2D duration, glycated hemoglobin level of 6.8–8.5%, taking metformin monotherapy were randomly assigned to glargine, glimepiride, liraglutide, or sitagliptin. HRQoL was evaluated at baseline in 4885 participants, and at years 1, 2, and 3 (Y1-Y3), using the Quality of Well-Being Self-Administered Scale (QWB-SA) and the 36-Item Short-Form Health Survey physical and mental component summary scales (PCS, MCS). Linear models analyzed changes in HRQoL over time in intention-to-treat analyses.

Results: None of the medications worsened HRQoL. There were no differences in QWB-SA or MCS by treatment group at any time point. PCS scores improved with liraglutide versus other groups at Y1 only. Greater weight loss during Y1 explained half the improvement in PCS scores with liraglutide versus glargine and glimepiride. Liraglutide participants in the upper tertile of baseline body mass index showed the greatest improvement in PCS scores at Y1.

Conclusion: Adding liraglutide to metformin in participants within 10 years of T2D diagnosis showed improvement in the SF-36 PCS compared with the other medications at 1 year, which was no longer significant at Y2 and Y3. Improvement was related to weight loss and baseline BMI.
Melanoma and LEOPARD Syndrome: Understanding the Role of PTPN11 Mutations in Melanomagenesis
Authors: Palacios-Diaz Rodolfo David , Pozuelo-Ruiz Mónica , De Unamuno-Bustos Blanca , Llavador-Ros Margarita , Botella-Estrada Rafael
Published: January 2024

Abstract is missing (Short communication)
POSITIVE SIGNALS OF TAX INCENTIVES FOR MICRO SMALL MEDIUM COMPANIES (MSEMs)
Authors: Zahro Maratus , Rahayu Rika , Kirana Ardilla Ayu
Published: January 2024

This research was conducted to test whether tax incentives provide a positive signal for medium-level companies. The research method used is descriptive qualitative by analyzing data as supporting data adapted to field case studies. The results obtained from this study: First, the results of the analysis show that from several tax incentive policies issued by the government, the most effective type of tax incentive for PT X is insentif PPh final PP No. 23 in 2018. because for small and medium companies this tax incentive can increase the company's cash inflow. Second, PPh 21 are not effective for small and medium companies because most of the employees at PT X have income below the PTKP, so it does not affect the purchasing power of employees. third, the withdrawal facility has an impact on the greater PPh 29 that must be paid, so it can be concluded that the PPh 25 withdrawal facility is only a delay. The cash inflow received during the use of this facility is only temporary. Fourth, the exemption from tax on dividends is a good signal for company managers and shareholders to immediately distribute dividends. This has been proven that PT X in 2021 distributed dividends of 1.8 billion Rupiah and 760 million Rupiah in 2022.
Exploration of the femtosecond laser pulse thermal effects on the mouse embryos during the assisted hatching procedure
Authors: Kubekina MV , Filatov MA , Silaeva YY , Sitnikov DS
Published: January 2024

Impaired hatching of the embryo from the zona pellucida (ZP), the specialized protective shell, immediately before implantation is one of the factors of infertility. Hatching impairment is often due to the ZP hardening or thickening. In such cases, the laser assisted hatching procedure is used to overcome infertility. During this procedure a hole is drilled in the ZP facilitating the embryo release. The question of the safe use of laser for assisted hatching remains open, since laser beam can heat the environment and cause thermal shock in embryos. The study was aimed to assess safety of the mouse embryo femtosecond laser exposure during the assisted hatching procedure using the embryo viability and HSP gene expression assessment methods. A new type of pulsed laser was used in the study for the ZP dissection — the femtosecond laser. The energy of such pulses was two orders of magnitude lower than the energy of laser dissectors currently used in the clinics. To assess the femtosecond laser exposure to the embryo, the house mouse (Mus musculus) embryos were stained with fluorescence dyes, and expression of the genes encoding heat shock proteins (Hsp90aa1 and Hspa5) was assessed. The embryonic cells remained viable after the laser assisted hatching procedure involving the use of a femtosecond laser, while expression levels of the genes encoding heat shock proteins were slightly increased compared to the negative control group (p = 0.408).
Artificial intelligence-based predictive maintenance, time-sensitive networking, and big data-driven algorithmic decision-making in the economics of Industrial Internet of Things
Authors: Kliestik Tomas , Nica Elvira , Durana Pavol , Popescu Gheorghe H.
Published: January 2024

Research background: The article explores the integration of Artificial Intelligence (AI) in predictive maintenance (PM) within Industrial Internet of Things (IIoT) context. It addresses the increasing importance of leveraging advanced technologies to enhance maintenance practices in industrial settings.
Purpose of the article: The primary objective of the article is to investigate and demonstrate the application of AI-driven PM in the IIoT. The authors aim to shed light on the potential benefits and implications of incorporating AI into maintenance strategies within industrial environments.
Methods: The article employs a research methodology focused on the practical implementation of AI algorithms for PM. It involves the analysis of data from sensors and other sources within the IIoT ecosystem to present predictive models. The methods used in the study contribute to understanding the feasibility and effectiveness of AI-driven PM solutions.
Findings & value added: The article presents significant findings regarding the impact of AI-driven PM on industrial operations. It discusses how the implementation of AI technologies contributes to increased efficiency. The added value of the research lies in providing insights into the transformative potential of AI within the IIoT for optimizing maintenance practices and improving overall industrial performance.
Reading the Tragic Smile Singularities of the Short Story Senyum Karyamin by Ahmad Tohari
Authors: Mulyani Via Ajeng , Praditama Angger Gilang , Purnomo Eko
Published: January 2024

Penelitian ini hendak menelaah mengenai ke-saling berbagi-an (the common) dan singularities dalam cerpen Senyum Karyamin karya Ahmad Tohari. Menggunakan pisau analisis Antonio Negri khususnya mengenai ke-saling berbagi-an (the common) yang merupakan wujud kekuatan biopolitis yang bersifat lentur melawan hegemoni kapital. Berangkat dari kisah para pengumpul batu yang senasib sepenanggungan di bawah kuasa tengkulak, rendahnya harga batu dan tanjakan licin yang setiap hari mereka lewati. Kondisi semacam itu membuat para pengumpul batu memiliki kemampuan biopolitis berkait ke-silih berbagi-an berupa menertawakan diri mereka sendiri. Sebagai the multitude dari rakyat kecil yang bekerja sebagai pengumpul batu, mereka saling berbagi tawa dan senyum yang mereka anggap sebagai simbol kemenangan atas tengkulak. Dalam hal ini, tokoh Karyamin sebagai salah satu subjek singular memiliki kemampuan berbagi motivasi, rasa, kepada orang-orang yang ditemuinya dalam situasi kelaparan akut dan hutang yang melilit. Kemampuan untuk tersenyum pada orang lain ketika situasi demikian barangkali merupakan suatu upaya pengembangan jejalin relasi sosial sekaligus penyelamatan diri. Meski pada akhirnya, kemampuannya berbagi senyum tetap tak dapat mengatasi kelaparan akutnya This research aims to examine the commons and singularities in the short story Senyum Karyamin by Ahmad Tohari. Using Antonio Negri's analytical knife, especially regarding the common, which is a form of biopolitical power that is flexible against capital hegemony. Departing from the story of stone collectors who share the same fate under the power of middlemen, the low price of stones and the slippery slopes they pass every day. Conditions like that make stone collectors have a biopolitical ability related to mutual sharing in the form of laughing at themselves. As the multitude of lowly people who work as stone collectors, they share laughter and smiles which they regard as a symbol of victory over the middlemen. In this case, Karyamin's character as a singular subject has the ability to share motivations, feelings, with people he meets in situations of acute hunger and heavy debts. The ability to smile at others in such a situation is perhaps an attempt to develop a network of social relations as well as self-rescue. Although in the end, his ability to share a smile still could not overcome his acute hunger
Una edición no identificada de la obra Libellus de octo orationis partium constructione de Erasmo de Rotterdam atribuida a John Colet (Barcelona 1578)
Authors: GIMÉNEZ ZÁLVEZ ROCÍO
Published: January 2024

Este artículo tiene por objeto la presentación y el estudio de la edición no identificada hasta el momento de la obra de Erasmo de Rotterdam Libellus de octo orationis partium constructione impresa por Sansón Arbús en Barcelona en 1578. Tras trazar una aproximación a la obra y a su tradición editorial, se ofrece la descripción material de esta edición y de su único ejemplar conservado (Biblioteca Civica Romolo Spezioli, Fermo), así como un acercamiento a la forma textual de la edición en relación con la tradición editorial previa en el contexto de las reacciones de la época contra Erasmo.
Xosé Antonio LÓPEZ SILVA, Historia Natural de Plinio. El bibliotecario del mundo, Madrid Guadalmazán, 2022, 600 páginas, ISBN 978-84-1754-759-2
Authors: García Jurado Francisco
Published: January 2024

Reseña ensayo de Xosé Antonio López Silva, Historia Natural de Plinio. El bibliotecario del mundo, Madrid Guadalmazán, 2022, 600 páginas, ISBN 978-84-1754-759-2
Inmaculada DELGADO JARA, Gramática griega del Nuevo Testamento. II. Sintaxis. Con clave comentada de las prácticas, Estella (Navarra), Editorial Verbo Divino, Colección Instrumentos para el estudio de la Biblia, 2023, 223 páginas, ISBN 978-84-9073-905-1,
Authors: Domínguez Cely Federico
Published: January 2024

Reseña de Inmaculada Delgado Jara, Gramática griega del Nuevo Testamento. II. Sintaxis. Con clave comentada de las prácticas, Estella (Navarra), Editorial Verbo Divino, Colección Instrumentos para el estudio de la Biblia, 2023, 223 páginas, ISBN 978-84-9073-905-1, ISBNE Ebook 978-84-9073-914-3, Depósito legal: NA 588-2023
Jeremiah COOGAN, Eusebius the Evangelist: Rewriting the Fourfold Gospel in Late Antiquity, New York, Oxford University Press, 2023, 234 páginas, ISBN 9780197580042
Authors: Seoane Zangrando Letizia
Published: January 2024

Reseña de

Jeremiah Coogan, Eusebius the Evangelist: Rewriting the Fourfold Gospel in Late Antiquity, New York, Oxford University Press, 2023, 234 páginas, ISBN 9780197580042
Dialog dan Kerjasama Antariman sebagai Upaya Pemaknaan Nilai Agama dalam Menangkal Radikalisme
Authors: Ziaul Haq Mochamad , Sari Yunika
Published: January 2024

This study aims to discuss the study of religion and radicalism in the realm that focuses on religion as conflict resolution and peacebuilding in an effort to ward off radicalism. This research method is qualitative in nature to describe and systematically interpret the facts of radicalism, using relevant literature study methods, which examine library sources such as research reports (thesis, journals), books and other supporting data related to the topic of religious radicalism, in addition to a descriptive analysis approach that places more emphasis on reviews related to the theme that has been determined and then described according to the formulation, and the results are summarized briefly and clearly. The discussion of this research includes the understanding of religious radicalism, indications and implications of radicalism, and religion as conflict resolution and peace. This study concludes that radicalism is an understanding that requires major changes and reforms by using violence. So there is a ned for conflict resolution to overcome or prevent the occurrence of radicalism, namely the concept of a religion of peace that presents the concept of inter-faith dialogue.
Investigating the effective indicators on the realization of good governance in border cities: A case study of Paveh, Iran
Authors: Mousavi Mir Najaf , Jafarpour Ghalehteimouri Kamran , Zadeh Robab Hossein
Published: January 2024

Border cities face significant challenges due to political, environmental, and social issues. Strong urban governance can help resolve many of these problems, but it requires identifying practical factors specific to each city’s location. This study aimed to assess the state of urban governance in Paveh, a border city with a population of 25,771 people. The research used both primary data collection (through a questionnaire) and secondary data sources (local and national databases and documents). The study randomly selected 379 households from Paveh’s population and determined a reliability value of 0.913 using the Cochrane procedure. To assess Paveh’s urban governance, eight criteria were used: participatory, rule-of-law compliance, transparency, responsiveness, consensus-oriented, equitable and inclusive, effective and efficient, and accountability. The findings revealed that Paveh’s urban governance, particularly in the dimensions of transparency and participation, is in an unfavorable situation.
Polidata: Modelo de inteligencia artificial para la evaluación del diseño de interfaz de usuario en dispositivos móviles
Authors: Santorcuato-Tapia MA. Lic. José Luis , Lloret Dr. Jaime
Published: January 2024

Dada la proliferación de chats y prompts para el uso de inteligencia artificial, especialmente en el ámbito del diseño y generación de contenidos, aparecen desafíos y oportunidades para el diseño. Este artículo propone la investigación y el desarrollo de un  modelo de aprendizaje profundo multiclase, destinado a evaluar el diseño de interfaz de usuario para dispositivos móviles, especialmente como apoyo durante el proceso de prototipado de interfaces en alta fidelidad. También, presenta la creación de un dataset o conjunto de datos destinado a ser la base de conocimiento del modelo. Se han seleccionado los ejemplos que constituyen el dataset, provienen desde aplicaciones para el sistema Android, empleando, como criterio de selección, la consistencia y estándares de ellas, para este propósito, se ha utilizado como guía de estilo el sistema de diseño Material Design de Google. El modelo se ha integrado a una interfaz que permite de manera intuitiva obtener las inferencias o el nivel de confianza frente a una interfaz diseñada que se le presente al modelo.
Conexión de la innovación y el diseño para potenciar la innovación en las empresas
Authors: Fernández Gago Paula , Martínez Rodríguez Rodrigo
Published: January 2024

Este trabajo estudia la conexión entre la innovación y el diseño desde varias ópticas y profundiza en la capacidad del diseño para potenciar innovaciones de producto y de proceso en las empresas. Para ello se analizan distintas definiciones de diseño, poniendo el foco tanto en el ámbito de la innovación a través del Manual de Oslo, como en el ámbito del diseño. Se busca evidencia sobre la conexión del diseño y la innovación en la literatura académica, en las políticas de la Comisión Europea y en las empresas. Por otro lado se muestra la importancia del sector servicios en la economía española y se conecta con la capacidad del diseño para contribuir a la generación de innovaciones de cualquier índole.
«Bellezas atroces». Fundamentos del juicio crítico sobre la calidad tipográfica
Authors: Cano Martín Laura , López Rubiño David
Published: January 2024

Este artículo es una revisión de las manifestaciones críticas vinculadas a las prescripciones relacionadas con el supuesto gusto tipográfico. El análisis se ha considerado en base a dos posiciones: la crítica sobre tipografías no recomendadas (o de mal gusto) y la recomendación de uso de tipografías entendidas como buenas tipografías (o de buen gusto). En base a los resultados obtenidos de dicha recopilación, se plantea una lista de doce variables que intervienen en la definición del criterio tipográfico.
El Faro clase: cómo hacer uso del b-learning en la asignatura de lengua y cultura francesas aplicadas a la traducción e interpretación
Authors: Valdenebro Sánchez Jorge
Published: January 2024

Este artículo versa sobre la realización de una propuesta docente llevada a cabo en la asignatura de «Lengua y cultura “C” aplicadas a la Traducción e Interpretación (IV) – Francés» del Grado en Traducción e Interpretación de la Universidad de Málaga (curso 2021-2022). Ante la imposibilidad de poder abordar cada uno de los bloques de la materia de manera presencial, nuestro deseo como docentes era poder trabajar alguno de los contenidos por medio de entornos virtuales de aprendizaje. El resultado de nuestra reflexión dio lugar a la concepción de la actividad El Faro clase, cuyo objetivo principal no era otro que cubrir las necesidades del bloque de léxico de la asignatura. Así, a lo largo de estas páginas presentamos cómo esta propuesta, inspirada en el programa de radio El Faro, vio la luz y se adaptó y aplicó a la asignatura objeto de este trabajo.
Análisis integral de las prácticas externas: Perspectiva de tutores y estudiantes
Authors: Rico-Belda Paz
Published: January 2024

El carácter formativo de las prácticas externas y su contribución a mejorar la empleabilidad del estudiantado hacen que resulte fundamental conocer cómo se desarrollan. Este trabajo se centra en analizar las prácticas externas de un doble grado impartido durante los cursos 2015-2016 a 2021-2022. El propósito de este análisis es extraer, de las encuestas a los tutores de empresa y al estudiantado, información relevante para conocer cómo se desarrollan las prácticas externas. El análisis de las encuestas, durante varios cursos, permite contrastar dos fuentes de información complementarias, además de proporcionar un análisis temporal del desarrollo de las practicas externas. La explotación estadística de las encuestas permite conocer, entre otros, el grado de satisfacción con las prácticas, el nivel de competencia alcanzado por el estudiantado y el grado de inserción laboral de las prácticas. Este conocimiento facilita a la Comisión de Prácticas incidir sobre aquellos aspectos mejorables de las prácticas externas.
Percepción sobre la orientación en el prácticum del máster de secundaria
Authors: Monzó Martínez Anna M. , Chocomeli  Fernandez M.  Fernanda , Martínez-Agut M. Pilar
Published: January 2024

Los departamentos de orientación realizan una labor fundamental en los centros de secundaria para la mejora educativa, la coordinación entre diferentes agentes de la comunidad educativa y de fuera de ella. En esta investigación se analizaron las percepciones de los estudiantes del prácticum del máster de secundaria de la especialidad de Física y Química sobre el papel que estos adquieren en los centros de secundaria. También se pretendió dar a conocer y poner en valor la aportación de estos profesionales, así como su contribución a la consecución de los Objetivos de Desarrollo Sostenible (ODS). Los resultados evidencian que el alumnado, durante su periodo de prácticas, ha advertido, en mayor medida, las funciones relacionadas con la atención a la diversidad, a la orientación tanto académica como profesional, y al apoyo al desarrollo personal del alumnado, así como su contribución, sobre todo, a los ODS 3 y 4.
Efectividad de una intervención educativa sobre la construcción de comunidades activas y saludables, en Bogotá-Colombia
Authors: Gonzalez-Cifuentes Silvia Alejandra , Domìnguez-Sànchez Maria Andrea , Gámez-Martínez Elda Rocio , Correa-Bautista Jorge Enrique
Published: January 2024

Comparar los cambios en conocimientos, actitudes y prácticas (CAP) de gestores y promotores en actividad física y deporte, posterior a una intervención educativa, en la construcción de comunidades activas y saludables (CCAS). Diseño cuasiexperimental pre y post-test sin grupo control. Se recopilaron datos auto diligenciados en 254 gestores y promotores de actividad física, recreación y deporte, pertenecientes a los programas comunitarios de Bogotá. La intervención educativa, se orientó a las temáticas en comunidad y promoción de estilos de vida saludables. Se evaluó los cambios en los (CAP) con relación a la (CCAS) mediante el programa estadístico JASP, versión 0.17.1. Los cambios en conocimientos y las prácticas sobre la CCAS mostraron diferencias estadísticamente significativas (p< ,001) entre el pre-test y post-test, luego de la intervención educativa (p< ,001). Las intervenciones educativas pueden considerarse como estrategias efectivas para capacitar en el modelo de CCAS.
La práctica aleatoria frente a la enseñanza sin errores en el aprendizaje del putt de golf en adolescentes
Authors: Gavala González Juan , Román Alconchel Blanca , Miranda León Mª Teresa , Fernández García José Carlos
Published: January 2024

El aprendizaje del putt de golf ha sido objeto de múltiples estudios, si bien en la franja de edad de la adolescencia apenas hay referencias de cómo plantear un proceso de aprendizaje que tenga el gradiente de desafío y la dificultad adecuada en contextos de aprendizaje en Educación Física (EF). Purpose: El objetivo de este estudio es investigar mediante una aproximación ecológica, si la práctica aleatoria (variabilidad) permite el aprendizaje del putt de golf en la iniciación deportiva al igual que el aprendizaje sin errores (repetitivo). Método: Han participado 46 estudiantes (M=13.8±.07años) de segundo curso de la enseñanza secundaria obligatoria (ESO), sin ninguna experiencia previa en este deporte. Se han tomado varias mediciones: a) pretest, b) tratamiento, consistente en siete bloques de práctica de 10 repeticiones, c) post-test y d) test de transferencia (dos semanas después del post-test). Resultados: Los datos nos indican que tanto el grupo de aprendizaje aleatorio (variabilidad) como el grupo de aprendizaje sin errores consiguen resultados parecidos tanto en el post-test (M=1,36, SD=0,32 vs M=

1,16 SD=0,30), como en el test de transferencia (M=2,56, SD=0,07 vs M=2,53, SD= 0,07). Conclusión: El aprendizaje de un gesto técnico tan complejo como es el putt de golf puede plantearse en estas edades y en la fase de iniciación tanto desde la variabilidad de la práctica como mediante la reducción del error y con una manifestación del nivel de aprendizaje parecido a corto y largo plazo.
El "lenguaje puro" y la traducción mística de Walter Benjamin
Authors: Silvestre Miralles Alicia
Published: January 2024

Walter Benjamin reflexiona en "La tarea del traductor" sobre el lenguaje y la traducción. Este trabajo tiene por objetivo principal evaluar la aplicabilidad de su teoría en el análisis de la obra Subida del Monte Carmelo de san Juan de la Cruz. Se ponen en relación los conceptos de su teoría para delimitar y comparar en qué medida pueden ser aplicados y averiguar en cuáles puntos concretos la teoría puede aplicarse a este género místico. Una aproximación inicial confirma la funcionalidad de conceptos como «lengua pura», «no comunicabilidad», entre otros, para la aprehensión de la obra del místico carmelita.
Anthology of Arabic Discourse on Translation
Authors: Solá Portillo Sara
Published: January 2024

Reseña de Anthology of Arabic Discourse on TranslationTarek Shamma y Myriam Salama-Carr (Eds.)Nueva York, Routledge, 2022, 399 pp.
Veleszületett rendellenességek epidemiológiája
Authors: Valek Andrea , Szabó Miklós
Published: January 2024

A veleszületett rendellenességek a test szerkezetének vagy működésének számos olyan rendellenességét foglalják magukban, amelyek a méhen belüli fejlődés során keletkeznek. Népegészségügyi jelentőségüket mutatja gyakori előfordulásuk, valamint az 5 éves kor alatti halálozásban játszott meghatározó szerepük. Az általuk okozott tartós megbetegedés nagy terhetró az érintett egyénekre, családjaikra és a társadalomra.A veleszületett rendellenességeket klinikai következményeik alapján major és minor kategóriákba sorolják. A morfológiai rendellenességek lehetnek izoláltak, amikor egy szervet vagy szervrendszert érintenek, és lehetnek több szervrendszert érintő multiplex rendellenességek. Megkülönböztetünk malformációs, deformációs, diszrupciós és diszpláziás elváltozásokat. A multiplex rendellenességek között előfordulnak szindrómák, asszociációk és szekvenciák. A kiváltó ok szerint két csoportba oszthatók: genetikai és nem genetikai eredetű, ún. teratogén ágens által okozott rendellenességekre. A teratogén ágensek lehetnek anyai betegségből eredők, fertőző kórokozók, fizikai behatások, valamint gyógyszerek és egyéb kémiai anyagok. Azonban a veleszületett rendellenességek nagy részének oka ismeretlen, mások pedig multifaktoriálisak lehetnek, azaz genetikai és környezeti hatások együttesen játszanak szerepet kialakulásukban. A közlemény az előzőleg felvetett meghatározások kiterjesztésével és részletesebb kifejtésével foglalkozik.
Performance Evaluation and Analysis of Cloud Attenuation Prediction Models for Satellite Transmission Quality Improvement
Authors: Adewusi Mustapha O. , Ometan Oluwafunmilayo O. , Akinwumi Oluwasayo A. , Omotosho Victor T. , Akinyemi Marvel L.
Published: January 2024

The reliability of social and business interactions on communication infrastructure determines the technological advancement of a nation. In the disclaimer notices of our financial institution’s transaction forms, they declared that they are not liable for communication channels malfunction that may lead to transaction interruption, transmission blackout and delayed services. Thus, effective hydrometeors attenuation margins are needed from accurate models to have reliable signal transmissions. Earlier research works established that increase in transmission frequency is directly proportional to attenuation on the signal, and that satellite communication unavailability in most tropical regions is above the allowed 1% outage percentage, significantly due to cloud attenuation contribution at satellite bands. The existence of clouds in tropical climates is almost perpetual, making cloud models all the more fundamental in tropical regions – which include Africa and about half of the rest of the world. The published new tropical cloud attenuation algorithm and its accompanying new tropical cloud attenuation model (NTM) - derived from it, is hereby further analysed with respect to wider frequency range. In the primary research to this work, data were collected from spectrum analyzer, weather-link and radiosonde equipment. The data were used to calculate values of projected attenuation by each major existing cloud model in the propagation range of 12 to 50 GHz. The predicted cloud attenuation values were spectrally processed and analysed. These results in the observation that the NTM’s predictions generally average the characteristics prediction values of existing models as shown by the graphical outputs. Also, the predicted attenuation values by each of the cloud models converge increasingly with frequency.
D-optimal chemical balance weighing designs with positively correlated errors: part II
Authors: Graczyk Małgorzata , Ceranka Bronisław
Published: January 2024

Some questions related to the problem of determining a chemical balance weighing design satisfying the criterion of D-optimality are considered. The theory is based on the assumption that the measurements are equally positively correlated and have the same variances. In this paper, we present a method of adding three measurements to a regular D-optimal chemical balance weighing designs to obtain a highly D-efficient chemical balance weighing design. The problem formulated in this way is an extension of results contained in a paper previously published in Biometrical Letters.
Epigenetics as a New Challenge in the Legal Field
Authors: Pečarič Mirko
Published: January 2024

The discovery of epigenetics as hidden external influences on genes could in the future affect all aspects of our lives. This includes also legal life, both in terms of its different application or enforcement of liability and the understanding of law itself. Epigenetics is a path towards personalised medicine, and with this to personalised and transgenerational justice. The aim of this paper is – based on the literature review and the critical evaluation of the material – to present epigenetics as a new legal perspective that allows a more personal perspective on issues of individual and transgenerational justice which brings to the fore intergenerational solidarity. The result of this is the increased awareness of the importance of changes in genetic profiles that can affect a person’s actions and thoughts, which can affect the way cases are handled. As epigenetics is focused on actual rather than chronological age, new discoveries on rejuvenation give us a new basis for a different interpretation and application of legal provisions. If the law changes during use and its violation (as proteins patch the DNA chain), thereby lowering the rule of law, an epigenetic view of the rejuvenation or reprogramming, resetting, and restarting of the DNA backup may offer a new-old, i.e. always baseline, perspective on the understanding of law.
Czech VAT Gap Progress
Authors: Kukalová Gabriela , Moravec Lukáš , Pfeiferová Daniela , Kuchařová Ivana , Marešová Kateřina
Published: January 2024

The article aims to estimate the VAT Gap amount development from 2010 to 2016 in the Czech Republic. The methodology of the VAT Gap identification was based on the indirect top-down method for each year of the reporting period, using the authors’ calculation of the weighted average VAT rate in the Czech Republic. The results of the years under review show a VAT gap of more than CZK 100,000 million per year. The breakdown of the VAT Gap into individual parts shows that it is mainly due to the intentional misrepresentation of data by business entities. The VAT Gap associated with this factor ranged from CZK 40,004 to CZK 52,765 million in the monitored years. Only 3.53%–7.03% of the VAT Gap of unlawful tax evasion is subject to prosecution for the tax evasion offense.
Hyponatremia: A Rare Complication of Gitelmans's Syndrome - Literature Review and Clinical Case
Authors: Stoian Marilena
Published: January 2024

Gitelman's syndrome (GS) is a variant of classical Bartter's syndrome (BS) in adults characterized by hypokalemic metabolic alkalosis, hypocalciuria (daily excretion <2.0 mg/kg body weight), hypomagnesaemia (<1.5 mg/dl), together with a normal to low blood pressure. In 1996, Simon et al. reported complete linkage between the syndrome and the thiazide-sensitive sodium chloride coporter (TSC) on chromosome 16q13 (Human Gene Mapping Workshop-approved symbol: SLCA3). Other metabolic features of GS include normonatremia, hyperuricemia, normocalcemia, increased plasma renin and aldosterone/potassium ratio, and inappropriately high renal potassium, magnesium, and chloride excretion. In this paper, we describe two affected patients who developed severe hyponatremia and hypouricemia. To the best of our knowledge, this complication has not been described previously.
A new two-parametric weighted generalized inaccuracy measure
Authors: Fayaz A. , Baig M. A. K.
Published: January 2024

In this article, we present a novel approach to measuring inaccuracy, introducing a two-parametric weighted generalized inaccuracy measure of order α and type β, along with its residual version. Our proposed measure depends on the proportional hazard rate model (PHRM) to uniquely determine the survival function, and we have derived a characterization result for this measure. Through our analysis under the PHRM framework, we have studied various properties of the proposed measure and their interrelationships.
Comparative Extraction of Components from Ukrainian and Baltic Ambers
Authors: Chornyi Valentyn , Krūma Zanda , Mysiura Taras , Popova Nataliia , Zavialov Volodymyr
Published: January 2024

The research is devoted to the issue of processing substandard amber to enable the use of the processing products in food, cosmetics, and pharmaceutical industries. For the first time, comparison was made of the extractive characteristics of amber from the two largest world deposits – the Baltic and Ukrainian. Nine times more dry substances are transferred to the extract from Ukrainian than from Baltic amber, when extracting amber with ethanol under the same conditions. The antioxidant activity of the obtained extracts was determined by ABTS+ and DPPH methods. The values of these indicators were higher in the extract of Ukrainian amber and also differed in extracts from different fractions. Analysis of the volatile components composition did not indicate a significant difference between the extracts of different amber, but clear differences were seen between the fractions from which the extract was obtained. The main component, representing more than a half of the volatile components, was o–Cymene. Most of the identified components are characterised by camphor odour. Amber from different places of origin have different extraction characteristics, which was confirmed by the research results.
Multi-institutional study of ‘Sandwich treatment’ for motor area large brain metastases (LBM) with diameter over 3 cm
Authors: Wang Zheng , Chen Haining , Chen Qun , Zhu Yucun , Li Min , Zhou Jia
Published: January 2024

Background

The objective of the present study was to explore the effectiveness and safety of ‘Sandwich treatment’ strategy for large brain metastases (LBM) with diameter over 3 cm (minimum volume >= 15 cm3) located in motor area.

Patients and methods

Patients from four gamma knife center that received ‘Sandwich treatment’ were retrospectively studied from January 2016 to March 2023. The strategy was one-week treatment course including 2 stages of stereotactic radiosurgery (SRS) and using bevacizumab once during SRS gap. The tumor volume and peri-tumor edema changes were analyzed before and after ‘Sandwich treatment’. Manual muscle testing (MMT) score and Barthel Index (BI) score were used to evaluate the changes of patients’ movement and physical strength rehabilitation. The patients’ overall survival (OS) and tumor local control (TLC) rate was calculated. Cox regression model was used to analyze the risk factors that related to TLC.

Results

61 patients with 72 lesions received the ‘Sandwich treatment’. The median prescription dose was 13.0 Gy and 12.5 Gy at the first- and second-stage SRS. The mean tumor volume at the time of ‘Sandwich treatment’ and 3 months later was 20.1 cm3 and 12.3, respectively (P < 0.01). The mean peri-tumor edema volume at the first- and second-stage SRS was 12.6 cm3 and 5.2 cm3, respectively (P < 0.01). Patients’ median MMT score improved from 6 at the beginning to 8 at the end of ‘Sandwich treatment’ (P < 0.01), BI score was also greatly improved from 45 at the time of ‘Sandwich treatment’ to 95 after 3 months (P < 0.01). Patients’ median OS was 14.0 months, and the 3, 6, 12 months OS rate was 92.0%, 86.0% and 66.0%, respectively. The TLC rate at 3, 6, 12 months was 98.4%, 93.4%, and 85.3%, respectively. Patients with lung cancer had lower risk of tumor relapse. The cumulative incidence of patient’s hemorrhage and radiation necrosis was 4.92% (3/61) and 13.11% (8/61) after ‘Sandwich treatment’.

Conclusions

‘Sandwich treatment’ strategy is safe and effective for LBM located in motor area. The strategy could rapidly improve the patients’ movement and enhance their physical strength rehabilitation.
Legal and ethical rules of plagiarism
Authors: LAZÍKOVÁ Jarmila , RUMANOVSKÁ Ľubica
Published: January 2024

Plagiarism has always been a problem in the university environment as well. There is no legal definition of plagiary, plagiarism or self-plagiarism in the national, supranational (EU) law or international agreements. The definition of plagiarism and selfplagiarism should be clear for academic staff and university students as well. We can conclude that the whole academic society agrees that plagiarism is a serious problem. The paper identifies the legal framework of plagiarism in the Slovak and EU law, the forms of plagiarism behind the legal framework and the problems arising from the use of - artificial intelligence (AI) and proposes solutions for how to fight against plagiarism in the academic environment. The Slovak declaration confirms the fact that existing legal regulations do not reflect the whole gamut of possible instances and circumstances of unscientific, unethical, and dishonest conduct. It seems to be necessary to prepare a directive in the EU law as a repressive measure to define which research conducts is not acceptable, including the AI considered often as a new form of plagiarism. As well as the training courses for teachers and students focused on plagiarism, including the AI and the possibilities for using it in academic research would be a preventive measure for avoiding plagiarism and selfplagiarism.
Efektivitas Teknik Forward Chaining Untuk Meningkatkan Kemampuan Menggosok Gigi Pada Anak Dengan Disabilitas Intelektual Kategori Ringan
Authors: Laililyah Fauziatul , Rusli Rusdi , Safitri Jehan
Published: January 2024

The study aims to investigate the effectiveness of forward chaining technique in improving the teeth-brushing ability in children with mild intellectual disability. The hypothesis is that the chaining technique with forward chaining method is effective in improving the teeth-brushing ability in children with mild intellectual disability. Intellectual disability is a disorder during a period of development characterized by deficits in conceptual, social and practical aspects of daily life. The forward chaining technique is a chaining method in which each activity is arranged coherently and becomes a small series by teaching the first steps to success. The research method was a quasi-experiment with one group pretest-posttest design, using the purposive sampling technique with the criteria of children with mild intellectual disability, aged 6-11 years, experiencing barriers to intellectual functions, being adaptive, and unable to brush their teeth. Data were collected using assessment, observation and interviews. The assessment test tools were the CPM and Binet tests. The instrument was an observation sheet. Data were analyzed using the Paired Sample t-Test with a result of 0.04, so the Ha was accepted. It is concluded that the forward chaining technique is effective in significantly improving the teeth-brushing ability in children with mild intellectual disability.
Kilka uwag o fonetyce ligi bałkańskiej
Authors: Bednarczuk Leszek
Published: January 2024

The focus of this article is the origins of (1) reduced vowels in languages of the Balkan Sprachbund, (2) lenition of soft stops, (3) its (pre)nasalization, (4) the change of ninto rin the Tosk dialect of Albanian and a similar process in Old Romanian as well as the Istro Romanian, Maramuresh and Oltenian dialects of this language, a parallel change of Latin linto rin common Romanian and certain Italian dialects.
Personzentrierte Systemtheorie
Authors: Kriz Jürgen
Published: January 2024

Gegenstand dieses Beitrags ist eine Darstellung der „Personzentrierten Systemtheorie“, wobei der Fokus weniger auf die Korrespondenz zu Modellen der interdisziplinären Systemtheorie gelegt wird, sondern eine an Erfahrungen orientierte Perspektive auf zentrale Prinzipien zum Verständnis klinischer und therapeutischer Prozesse gewählt wird. Das Interesse richtet sich dabei insbesondere auf Prozesse der Generierung und Veränderung von Sinn und Bedeutung sowie deren Verflechtung auf unterschiedlichen Systemebenen – Interdependenzen zwischen körperlichen, psychischen, interaktiven und gesellschaftlich-kulturellen Prozessen. Sinn ist eine Reduktion kognitiver Komplexität, wie auch Interaktionsmuster chaotisch große Handlungsräume ordnen. Die Selbstorganisation solcher dynamischer Ordnungen ergibt sich aus der Unterstützung bei der Realisation inhärenter Möglichkeiten. Dies steht im Gegensatz zur typischen Alltagsvorstellung, dass Ordnung stets fremdorganisiert von außen geschaffen werden muss. Sie entspricht aber genau dem, was im Personzentrierten Ansatz von Rogers als Aktualisierung bzw. Selbst-Aktualisierung thematisiert wird. Es wird gezeigt, dass die Aktualisierungstendenz keine Frage des Glaubens ist oder es sich um eine Annahme in Rogers Theorie handelt, sondern schlicht um eine Beschreibung der Konsequenzen die sich ergeben, wenn man Vernetzung und Beziehung in Prozessen ernst nimmt.
Modeling and simulation of absorption solar air conditioning to reduce energy consumption: A case of some cities in tropical region
Authors: Nematchoua Modeste Kameni , Yvon Rakotondrazano , Chrysostome Raminosoa
Published: January 2024

Buildings are one of the most important infrastructure sectors in today’s society. However, in Madagascar, most hotels, malls, hospitals use fossil fuels to meet energy needs, especially in the traditional air conditioning system. they consume a considerable amount of energy that has negative effects on the environment. The emergence of solar cooling systems is a very interesting solution to this problem because the use of renewable energies in this sector contributes to a significant reduction of greenhouse gas emissions in the environment. Madagascar is one of the countries with high renewable energy potential, notably solar energy estimated at 2000kWh/m².an.At present, the rate of exploitation of this potential for the operation of the solar absorption cooling system coupled with the building is still non-existent. This energy is clean, sustainable, profitable and environmentally friendly. This is the main objective of this work which uses this energy source to ensure thermal comfort in a building in Madagascar and contributes to the development of this system. The TRNSYS software helped us to model and simulate this system.  To do this, first we will select 4 big cities of the big island, a building of total surface 80 m² was used. Then, the hourly thermal loads of this building for the whole year were simulated using the TRNbuild sub-program using meteorological data for a typical year of the selected cities. The dimensions of the components of the solar absorption air conditioning system were obtained using the maximum loads of the building. The results of the simulations show, the system meets the cooling load needs of the building with the climatic conditions of each selected city.
Application of machine learning methods to counter insider threat to information security
Authors: Strizhkov Vladislav Alexandrovich
Published: January 2024

The subject of the study is the problem of internal threats to information security in organizations in the face of malicious insiders, as well as negligent employees. The object of the study is machine learning algorithms in terms of their applicability for detecting abnormal behavior of employees. The author delves into the problems of insider threat, and also considers various approaches to detecting malicious user actions, adapting these concepts to the most suitable machine learning algorithms in terms of functionality, implemented further in the framework of the experiment. The emphasis is on the insufficiency of existing generally accepted security measures and policies and the need to improve them through new technological solutions. The main result of the conducted research is an experimental demonstration of how controlled machine learning and data mining can be effectively used to identify internal threats. During the experiment, a realistic set of input data is used, compiled on the basis of real cases of insider activity, which makes it possible to evaluate the operation of machine learning algorithms in conditions close to combat. When comparing the results obtained, the most efficient algorithm is determined, which is preferable for future studies with a larger data set. A special contribution of the author is a fresh look at the understanding of the insider threat and an experimentally substantiated argument in favor of a new approach to countering this threat, combining a complex of diverse measures. Thus, the work involves both mathematical methods on which the logic of machine-learning algorithms is based: classification, regression, adaptive enhancement, etc., and linguistic methods used for preprocessing the input data set, such as stemming, vectorization and tokenization.
Criticism of modern approaches to the interpretation of the concept of «threat» in technical disciplines: elements of theoretical absurdity of some researchers' ideas
Authors: Massunov Sergei L'vovich
Published: January 2024

In the presented work, the subject of research is one of the main categories of the conceptual apparatus of such a new direction of theoretical thought as the science of safety - the concept of «threat». Despite the obvious simplicity of this term and its widespread use in everyday life and legal practice, disputes about its substantive basis do not stop in the scientific community. Insufficient elaboration of the main categories of safety theory leads to numerous ambiguous interpretations of its fundamental terms, which do not allow forming a strictly defined theoretical basis. Therefore, in this article, using the example of the analysis of publications published in scientific journals and on the «AGA-Sofia»s website, the most obvious shortcomings of existing approaches to the interpretation of the concept of «threat» and its main characteristics are revealed. The solution of the tasks set in the work is based on the application of methods of logical analysis, laws of terminology and methodological principles of philosophy. The paper draws attention to the fact that, unlike the general case, when a threat is formulated as the intention (possibility) of causing any harm to someone / something (the object of the threat) on the part of someone/something (the source of the threat), in technical disciplines, the threat is presented as the possibility of harmful consequences as a result of object–object/subject relations (the impact of something on someone/something). Among the identified shortcomings in the interpretation of the characteristics of the threat, it is emphasized that it does not necessarily have to be manifested. If the threat is real, it can be both explicit and hidden. In addition, its potential form is legitimate, due to the two-dimensionality of the universal «possibility». At the same time, the author draws attention to the grossest methodological miscalculation made by some researchers - the threat cannot be a phenomenon, since it represents only the possibility of harmful consequences of any phenomenon. The article draws attention to the fallacy of attempts by some authors to extend the scope of the definition of «threat» to the concepts of «blackmail» and «ultimatum», as well as to the possibility of perception responses when harm is caused as a result of the threat. The inaccuracies allowed by researchers in defining the term «threat source» are analyzed, and the validity of the use of certain terms closely related to the concept of threat, such as «threat to the safety of the object», «threat to interests», «threat of unauthorized access» is justified.