bluuebunny/crossref_metadata_2025 huggingface dataset:
Hope and Spirituality of an AF in Kazuo Ishiguro’s Klara and the Sun
Authors: Aiman Azeem  , Sarvajit Mukerji
Published: December 2024

It has long been believed that emotions are a distinctive feature of humans. In a world where artificial intelligence (AI) is becoming increasingly ingrained, it’s intriguing to consider a time when AI may feel emotions similar to those of human beings. AI systems’ evolution and incorporation of emotional quotient will result in AI that, when a new skill is mastered or a task is completed effectively, it might also feel happy or satisfied. This AI may experience feelings of sadness or disappointment, which, in theory, might motivate it to look for more effective solutions or to convey the severity of the problem more clearly. AI will probably have a stream of consciousness, the same as humans. Klara and the Sun (2021) by Kazuo Ishiguro is set in a future where artificial intelligence and human life meet. Human-like robots, known as “Artificial Friends” (AFs), are created to serve as companions for children. Klara, the central character, is an AF with a unique perspective on the world. The novel explores complex questions about what it means to be human and AI with emotional quotient. This research article attempts to analyze the novel’s underlying themes of hope and spirituality, particularly Klara’s belief in the sun, from the philosophical perspective of a humanoid.
LEUCEMIA MIELOIDE CRÔNICA: AVANÇOS EM DIAGNÓSTICO, TRATAMENTO E PROGNÓSTICO
Authors: Oliveira Carlos Walmyr de Mattos , González Ana Laura Peña , Bezerra Ana Raisa Salles , Rodrigues Alex Oliveira , Sousa Lizia Maria Pessoa de , Gonçalves Alex Gabriel Tenório , González Ana Paula Peña , Mancini Alicia Ferreira
Published: December 2024

A leucemia mieloide crônica (LMC) é uma neoplasia hematológica caracterizada pela proliferação descontrolada de células mieloides, frequentemente associada ao cromossomo Philadelphia e à fusão do gene BCR-ABL. O tratamento com inibidores de tirosina quinase (TKIs), como o imatinibe, trouxe avanços significativos, melhorando a sobrevida e a qualidade de vida dos pacientes. Este artigo realiza uma revisão sistemática da literatura sobre LMC, focando em estudos dos últimos 20 anos que abordam diagnóstico, tratamento e prognóstico da doença. A pesquisa foi conduzida em bases de dados eletrônicas, resultando na seleção de artigos que foram avaliados quanto à qualidade metodológica e organizados em categorias temáticas. Os principais métodos diagnósticos incluem hemograma, biópsia de medula óssea e análise citogenética para identificar a presença do cromossomo Philadelphia. Apesar do sucesso inicial dos TKIs, a resistência ao tratamento e a progressão da doença para fases aceleradas ou blásticas continuam a ser desafios significativos. Modelos prognósticos, como as pontuações de Sokal e EUTOS, são fundamentais para a estratificação de risco dos pacientes e ajudam a guiar as decisões terapêuticas. O transplante alogênico de células hematopoiéticas permanece como a única terapia potencialmente curativa, especialmente em casos de resistência ao tratamento com TKIs. No entanto, a seleção cuidadosa dos pacientes é essencial, devido às complicações associadas ao procedimento, como a doença do enxerto versus hospedeiro (GVHD). A revisão destaca a importância de uma abordagem multidisciplinar e da pesquisa contínua em novas terapias, como combinações de TKIs com imunoterapia, para otimizar os resultados em pacientes com LMC em fase avançada ou com resistência a tratamentos anteriores. Em suma, a busca por uma cura definitiva e a melhoria dos resultados a longo prazo continuam sendo prioridades na pesquisa oncológica.
IMPACTO DA DOENÇA REUMÁTICA CRÔNICA DO CORAÇÃO NO BRASIL: UM ESTUDO PELA PERSPECTIVA DO SUS
Authors: Alves Alice Fermiano , Pereira Pedro Henrique Saldanha , Vidal Tallitha Grawnth Santos , Schulz Maria Eduarda Bonetti , Carvalho Luiza Barreto de , Pinho Marcus Levi Braga , França João Vitor Tavares
Published: December 2024

INTRODUÇÃO: A doença reumática crônica do coração (DRC) é uma complicação relevante da Febre Reumática, responsável por um terço das cirurgias cardiovasculares no Brasil. Apesar disso, há escassez de estudos que descrevam as características dos pacientes com cardiopatia reumática crônica em diferentes regiões do país. OBJETIVO: Mapear as ocorrências e analisar a epidemiologia da RDC, contribuindo para aprimorar ações de diagnóstico e tratamento. METODOLOGIA: Estudo epidemiológico ecológico com dados secundários sobre morbimortalidade por DRC entre 2018 e 2022, extraídos do DATASUS via Sistema de Informações Hospitalares (SIH/SUS). RESULTADOS: No período analisado, ocorreram 5.528.773 internações por doenças circulatórias, das quais 33.791 (0,61%) foram atribuídas à DRC. A maior incidência foi na região Sudeste, com 13.408 casos (39,68%), seguida do Nordeste, com 10.922 (32,32%). As faixas etárias mais acometidas foram de 50-59 anos, com 7.836 internações (23,19%), e de 60-69 anos, com 7.261 (21,49%). CONCLUSÃO: Os dados reforçam a relevância do diagnóstico e tratamento precoce da DRC para reduzir internações e gastos no sistema de saúde. Além disso, são necessários estudos mais aprofundados sobre as causas, diminuindo as complicações, a mortalidade e o impacto na saúde pública.
DIFERENCIAR-SE: A(S) INFLUÊNCIA(S) DAS RELAÇÕES FAMILIARES NO PROCESSO DE INDEPENDÊNCIA E AUTONOMIA DE JOVENS
Authors: Moro Marianna Zampier , Kissula Julia Chiminecki
Published: December 2024

O artigo tem como objetivo investigar como os padrões de comportamento intergeracionais e as dinâmicas familiares afetam a capacidade dos jovens de alcançarem a independência, à luz da teoria da diferenciação do self de Murray Bowen. Utilizando uma revisão narrativa da literatura baseada no trabalho original de Bowen e em sete artigos científicos, o estudo explora o conceito de diferenciação do self entre jovens adultos, compreendido como a habilidade de equilibrar autonomia e vínculo emocional com a família de origem. Esse processo é essencial para a formação da identidade individual e a construção de relacionamentos fora do ambiente familiar, exigindo que o jovem desenvolva uma identidade emocional independente, ainda que conectada aos familiares. A pesquisa indica que relações parentais funcionais facilitam a autodiferenciação, oferecendo apoio sem imposição de expectativas rígidas, o que promove a independência emocional e o bem-estar. Jovens com maior autodiferenciação demonstram melhor satisfação pessoal e relações familiares mais harmoniosas, enquanto aqueles oriundos de famílias com emaranhamentos emocionais tendem a enfrentar desafios nesse processo, perpetuando dependências emocionais. Contudo, a escassez de estudos empíricos e de traduções das teorias de Bowen para o português dificultara o acesso ao conhecimento sobre diferenciação do self e sua conexão com o funcionamento familiar, apontando para a necessidade de mais pesquisas que embasem intervenções clínicas eficazes, promovendo a saúde emocional e relações familiares funcionais com foco na autonomia e na comunicação.
O IMPACTO DO TRATAMENTO PALIATIVO NOS FAMILIARES: UMA PESQUISA EXPLORATÓRIA
Authors: Diedrich Rafael Augusto , Perufo Carlos Eduardo , Prudente Regina Lucia de Oliveira , Santos Lucimaira Cabreira dos
Published: December 2024

Esta pesquisa demonstra que o tratamento de um familiar em cuidados paliativos gera impacto aos familiares cuidadores. O objetivo desta pesquisa foi identificar e analisar os impactos aos familiares que podem decorrer dos cuidados paliativos, analisando possíveis impactos emocionais, sociais e psicológicos, e relacionando-os às relações familiares. Como metodologia de pesquisa, realizou-se uma pesquisa exploratória transversal de cunho misto para a coleta de dados com uma entrevista qualitativa semiestruturada e um questionário quantitativo como instrumentos. Já como metodologia de análise, utilizou-se da análise temática, que é uma das técnicas dentro da análise de conteúdo, além de uma tabulação em planilhas dos dados utilizados para melhor visualização por meio de tabelas. Além disso, conceitos como cuidados paliativos e impactos psicológicos foram apresentados para melhor entendimento do tema proposto, juntamente com uma breve introdução que dialoga com pesquisas, estudos e bibliografia sobre o tema. Concluiu-se que o tratamento de cuidados paliativos pode ser um fator de agravamento no bem-estar, podendo gerar angústia e impactos nas esferas sociais, emocionais e psicológicas dos familiares. Por outro lado, observa-se que os participantes com uma rede de apoio funcional, bem como um suporte profissional adequado, e que recebem acompanhamento de longo prazo, conseguem, em grande parte, lidar melhor com os desafios e dificuldades que se apresentem ao longo do tratamento. Por fim, observou-se a importância da presença de profissionais da área da psicologia nestes contextos, demonstrados pelos relatos de participantes que receberam apoio psicológico, resultando numa amenização dos impactos e melhora da qualidade de vida.
Iniciativa institucional: “abre tu puerta al cuidado de la población migrante internacional. Salud para los nuevos bogotanos y bogotanas: un asunto de derechos"
Authors: Curiel Iliana , Reyes Yolima
Published: December 2024

A partir de la crisis migratoria desde Venezuela, la cual se ha documentado como el éxodo más grande que se ha registrado en el hemisferio occidental en los últimos 50 años, según el Alto Comisionado de las Naciones Unidas para los Refugiados - UNHCR (2020) (RMP.R4V.INFO, 2023), situación que ha conllevado a vulnerabilidades en la población repercutiendo en su situación de salud, lo que ocasiona una gran demanda de atenciones, siendo un gran reto desde el Estado garantizar el derecho fundamental a la salud, a personas que ingresan en calidad de migrantes al país, ya sean estos nacionales de otros países, o bien, a colombianos de origen que están retornando a su patria. Por lo cual, como respuesta a esta dinámica migratoria, el Estado ha implementado acciones para la integración de los individuos en los territorios y comunidades afectadas por el fenómeno migratorio desde la República Bolivariana de Venezuela. En este contexto nacional, la Secretaría Distrital de Salud de Bogotá, atendiendo a la necesidad de impactar la gran demanda de atenciones y la situación en salud dada por el fenómeno migratorio, planteó una iniciativa de respuesta institucional que permitiera garantizar sus derechos en salud. Iniciativa que incluye como líneas de trabajo: planteamiento de intervenciones estratégicas, construcción de documentos técnicos de abordaje integral a la población migrante internacional, espacios de articulación, coordinación institucional e intersectorial, fortalecimiento de sistemas de información y generación de conocimiento para la toma de decisiones; así como el desarrollo de atenciones individuales, colectivas y poblacionales diferenciales.

El desarrollo de esta iniciativa con sus componentes ha permitido impactar de manera positiva el estado de salud de las personas extranjeras en el Distrito Capital.
İzlerken Al Özellikli Ürün Yerleştirme Uygulamaları: 4N1K Yeni Başlangıçlar Örneği
Authors: Sundurdu Seden
Published: December 2024

Her “yeni” iletişim aracı, yalnızca iletişim alanını değil, aynı zamanda reklamcılık gibi kitle iletişimini kullanan pek çok farklı sektörü etkilemektedir. İnternet teknolojilerindeki gelişmeler yeni reklam alanları yaratmış, buna paralel olarak hem yeni reklam türleri ortaya çıkmış hem de var olan reklam türlerinde birtakım dönüşümler yaşanmıştır. Bu reklam türlerinden biri ürün yerleştirmedir. Günümüzde ürün yerleştirme uygulamaları, çevrim içi yayınlarda izleyicilerin sahnede gördükleri ürünleri, doğrudan aynı ekrana tıklayarak satın alabilecekleri “izlerken al” özelliğini taşıyabilmektedir. Bu özellik, ikinci ekran uygulamalarından farklı olarak, ikinci cihazın varlığına olan ihtiyacı ortadan kaldırmaktadır. Araştırmada Türkiye’de daha önce herhangi bir çalışmaya konu olmamış “izlerken al” özelliği incelenmekte ve bu özelliğin nasıl kullanıldığı konusunda durum tespiti yapmak amaçlanmaktadır. Bu bağlamda araştırma soruları, izlerken al özellikli ürün yerleştirmelerin süreleri, ürünün sektörü, markası ve yerleştirme stratejisinin ne olduğu ile yerleştirmelerin sıklığını ölçmek üzerine kurulmuştur. İzlerken al özellikli ürün yerleştirmeleri araştırmak üzere, Türkiye’nin ilk izlerken al özellikli dizisi 4N1K Yeni Başlangıçlar seçilmiştir. Dizinin tüm bölümleri araştırmaya dahil edilmiş, metin içerik analizi tekniğiyle incelenmiştir. Çözümleme sonucunda, izlerken al özelliğine sahip ürün yerleştirme uygulamalarının, geleneksel ürün yerleştirme uygulamalarından farklı olarak belirli bir zaman aralığıyla sınırlı olmadığı, bölüm boyunca erişilebilir olduğu görülmüştür. İzlerken al özellikli ürün yerleştirmelerin sektörlere göre dağılımı incelendiğinde, beyaz eşya ve küçük ev aletleri ilk sırada yer almıştır. Araştırmanın markalara ilişkin analiz bölümünde, sektöre ilişkin bulgulara paralel olarak, Vestel’in en çok reklam veren marka olduğu görülmüştür. İzlerken al özellikli ürün yerleştirmesi yapılan bazı ürünlerin markasının bulunmadığı, markası belirtilmeyen bu ürünlerin tersine ürün yerleştirmelerinin yapıldığı tespit edilmiştir. Uygulamaların %90,94’ünün görsel yerleştirme olduğu saptanmıştır.
Diagnóstico y manejo de la apendicitis no perforada: revisión de la literatura
Authors: Vega Tenesaca Yessenia Marisol , Yacelga Araguillin Katherine Andrea , Celi Yanangómez Verónica Nathaly , Morales Tashintuña Carlos Javier , Acosta Salazar Karen Vanessa , Tipán Iza Alex Antonio , Chicaiza Alomoto Richar Alonso , Mafla Maza Karen Dominique
Published: December 2024

La apendicitis, que es la inflamación del apéndice vermiforme vestigial, representa una de las causas más habituales del abdomen agudo y una de las razones más recurrentes para realizar cirugías abdominales de emergencia a nivel mundial. El análisis de las personas con sospecha de apendicitis se enfoca en identificar de manera temprana a quienes padecen apendicitis aguda mientras se procura reducir al mínimo la cantidad de cirugías laparoscópicas o laparotómicas innecesarias. Un diagnóstico erróneo de apendicitis, particularmente si ya se encuentra perforada, puede conllevar resultados severamente negativos para el paciente, mientras que las cirugías no terapéuticas generan morbilidad sin abordar la causa subyacente. Por más de cien años, la apendicectomía abierta era el tratamiento estándar para la apendicitis. Hoy en día, las estrategias actuales son más complejas y refinadas: la apendicectomía laparoscópica ahora supera a la abierta en frecuencia, algunos pacientes con apendicitis perforada pueden beneficiarse al comenzar con tratamiento antibiótico preliminar seguido de apendicectomía diferida, y se han realizado ensayos que indican que tratar la apendicitis no complicada solo con antibióticos podría ser viable.
Pragmatic Analysis of Flouting Maxim in Romantic Dialogue: A Case Study of Dilan 1990
Authors: Saefudin Dery Purnama , Santosa Prima Pantau Putri , Lutvaidah Ukti , Restoeningroem Restoeningroem , Albab Suhfi , Puadah Adah
Published: December 2024

Dilan 1990 is a popular Indonesian film known for its romantic dialogue and engaging narrative. This study analyzes the use of flirtatious remarks within the film through Grice's Cooperative Principle, focusing specifically on the concept of flouting his four maxims: Quantity, Quality, Relevance, and Manner. The analysis reveals that the maxim of Relevance is most frequently flouted (18 instances, 32%), followed by Quantity (17 instances, 30%), Quality (15 instances, 26%), and Manner (7 instances, 12%). This pattern suggests that the characters prioritize emotional expressiveness and romantic appeal over strict adherence to conversational norms. The flirtatious remarks often manipulate language strategically to heighten romantic tension and evoke humor, which significantly contributes to the film’s charm and cultural resonance. These findings provide valuable insights into the pragmatic strategies of flouting used in romantic discourse and their impact on viewer engagement and narrative effectiveness, highlighting the complexities of youthful romance.
PERBANDINGAN DESAIN PENGERING BERBASIS EFEK RUMAH KACA VARIASI CEROBONG PENGHAWAAN: IMPLEMENTASI PADA MASYARAKAT LOKAL
Authors: Djamalu Yunita
Published: December 2024

Greenhouse effect-based dryers are an efficient and environmentally friendly technological solution to improve the quality and added value of agricultural and fishery products. This research aims to analyze the comparative technical and economic performance of three variations of ventilation chimney designs, namely conventional, thermal, and multidirectional, in their implementation in local communities. Research methods include field experiments to measure technical parameters, such as temperature, humidity, drying time, and airflow speed, and economic analysis to calculate investment costs, payback period, and net profits. The results showed that the thermal chimney provided the best performance with an average temperature of 50°C, drying time of 21 hours, and high airflow efficiency, suitable for rural areas. Multidirectional chimneys are more flexible against unstable wind conditions, making them ideal for coastal areas. This technology is environmentally friendly with a reduction in carbon emissions of up to 1.2 tonnes of CO₂ per year per unit. The novelty of this research lies in the combination of innovative design, in-depth economic analysis, and the application of technology that is adaptive to local needs and challenges, making it relevant and beneficial to society and the environment. In conclusion, a greenhouse effect-based dryer with a ventilation chimney design is a technology that is feasible to apply to increase productivity, environmental sustainability, and the welfare of local communities.
O IMPACTO DA EDUCAÇÃO EMOCIONAL NO DESEMPENHO ACADÊMICO DOS ALUNOS
Authors: Júnior Hermócrates Gomes Melo , De Almeida Evaristo Fernandes , Dos Santos Ana Maria Viana Guerra , Mafra Mackson Azevedo , Miranda Laura Elice de Souza Ferreira , Martins Karla Patrícia Costa , Otani Tatsue dos Santos , Passos Luiz Marcelo
Published: December 2024

This study addressed the implementation of emotional education in schools, seeking to respond to the problem of the insufficiency of these practices and their impacts on student development. The general objective was to analyze how emotional education contributes to the personal and academic development of students. The methodology adopted consisted of a literature review, in which several academic sources on the subject were consulted. The results indicated that the integration of emotional education into the school curriculum results in improvements in students' socio-emotional skills, in addition to influencing their academic performance and interpersonal relationships. The analysis revealed that interventions involving parental participation were effective, evidencing the relevance of family support in the continuity of emotional learning. In the final considerations, the study emphasizes the need for institutional commitment so that emotional education practices are systematically implemented in schools. The research also pointed to the urgency of further research that explores different approaches and contexts of implementing emotional education, aiming to improve existing interventions.
Septal extensor 2024 with costal cartilage: the use of aesthetic parameters and dynamics, in primary Rhinoplasty, an advanced surgical technique of the nasal tip
Authors: Lema Balla Jose Roberto , Lara Jácome Alex Gabriel , Cordero Carvallo Cristian Ernesto , Pilalumbo Choloquinga Edwin Rubén , Ante Loor Mayra Alejandra , Venegas Ortiz Yolanda Maribel , Orbea Tovar María José , Lema Balla Juan Carlos
Published: December 2024

Adjusting the lower third of the nose can be considered the most complicated part of nose surgery.  The caudal septal edge is usually located behind the nasal spine without direct contact; Additionally, thick skin contributes to limited definition of the nose, especially at the nasal tip. Repairing these problems and their consequences represents a genuine challenge for the cosmetic surgery surgeon, especially considering the importance of correcting imperfections in the bone and cartilaginous structure of the nose, including alterations in the nasal cartilages themselves, such as the partial or complete lack of the same, which may be the result of a process of absorption or necrosis of the tissues. The purpose of this document is to explain the use of costal cartilage as implant in the nasal tip during a primary rhinoplasty as part of aesthetic surgery of the nose, with the purpose of supporting an innovative technique called Septal Extender 2024. A novel surgical technique is presented and also carried out a retrospective descriptive analysis by reviewing medical records, surgical procedures for primary nasal tip rhinoplasty with Septal extender 2024.
Knowledge of research and scientific publication in medical students
Authors: Carías Alejandro , Auza-Santivañez Jhossmar Cristians , Carias Pablo , Condori Villca Nayra , Vallejos-Rejas Daniel Ramiro Elías , Velez Alejo Roy Wilson , Carvajal-Tapia Aaron Eduardo
Published: December 2024

Medical schools prepare students in academic knowledge, sometimes without introducing them to the research process. Objective: to analyze the knowledge in research and scientific publication of medical students in social service, 2023. Methods: quantitative, correlational study, sample of 84 students, through non-probabilistic convenience sampling, statistical analysis was performed with SPSS version 25 doing descriptive analysis of central tendency, grouping, and inferential with p value = 0.05 using Pearson's R test. Results: 64.3% participants reported having knowledge about research methodology, of those 39.3% had average knowledge of research methodology. 8.3% acknowledged having at least one scientific publication made, of them, 2.3% with high knowledge. 53.6% reported having participated in some scientific research, of which 8.3% had a scientific publication, with p value=0.014 (0.012-0.016). 64.3% of participants reported having knowledge about research methodology, of which 40.4% reported having participated in some scientific research, with p value=0.024 (0.021 – 0.026). Conclusions: There is no correlation between knowledge of scientific research and publication for undergraduate students, about to complete their studies, however there is a correlation between participation in scientific research and publication, and knowledge of scientific research and participation in research; which opens the door to the hypothesis that knowledge of scientific research does not allow them to publish on their own, in addition, that they do not feel interest or do not perceive a benefit in achieving research and publishing before graduating from the degree
SME in Albania: A Descriptive Analyses of Business Environment Based on SME Policy Index
Authors: Thoma Ledia , Boshnjaku Anila , Dafa Juna
Published: December 2024

Micro, small and medium enterprises make an important contribution to the economic development of Albania. Due to globalization and EU integration process, business environment in our country is becoming more and more complex and SMEs have to undertake proper actions in order to compete at national and international markets. Under these circumstances, more attention should be paid to innovation as the main tool to remain competitive in a globalized world. This paper aims to provide a descriptive analysis of SMEs sector in Albania focusing on their contribution to the national economy as well as of the environment where this type of businesses operates. Analysis is based on secondary research and the majority of data used are mostly retrieved SME Policy Index, a benchmark tool designed to assess policies that support small and medium-sized enterprises (SMEs) in emerging economies and monitor progress in policy implementation over time. Over the last years, significant progress is made toward the establishment of the proper business environment for SMEs in Albania Government policies and initiatives seem to have produced concrete results with regard to some specific indicators institutional and regulatory framework for SME policy making; operational environment for SMEs; public procurement; standards and technical regulations; and internationalisation of SMEs
 
 
Received: 30 September 2024 / Accepted: 28 November 2024 / Published: 3 December 2024
The subjective experience of an impasse in psychotherapeutic interaction
Authors: Stepanova Tatiana A.
Published: December 2024

This article is devoted to the metaphorical description of the subjective world of a person experiencing an intrapsychic or interpersonal impasse. Based on the work “Impasse and Intimacy: Applying Berne’s Concept of Script Protocol” by W.F. Cornell and M.N. Landaiche (2006) the author of the article gives a brief overview of the phenomenon of an impasse, which can occur both in the client’s inner world and in the interaction between the psychologist and the client. In the latter case, the impasse acts as an interpersonal process that disrupts the work of a psychotherapeutic alliance. The uniqueness of living both an individual impasse and an impasse arising in a therapeutic relationship depends on individual unconscious relational patterns (primal protocols).
In the article, the author’s attention is more focused on the subjective experiences of a person who is in a state of impasse, including the examples of mythology. Throughout its development, humanity has had many experiences of being in the impasses and getting out of them, and has captured these experiences, along with other products of the collective unconscious, in myths, legends, and fairy tales.
Understanding the subjective experience of an impasse is very important from the point of view that the primal protocol is not verbalized by the client, therefore images, metaphors, metaphorical stories can help bring the living of this experience into a verbal plan, allowing us to discuss what is happening.
The statements of clients describing the inner experience of impasses are given with their consent.
CONTRIBUIÇÕES AO TURISMO DE OBSERVAÇÃO DE AVES
Authors: Bonfim Alan Ferreira , Almeida Renato de , Santos Juracy Marques dos , Nogueira Eliane Maria de Souza
Published: December 2024

A relação histórica entre aves e humanos é crucial, envolvendo manifestações culturais e subsistência. O Brasil destaca-se como o terceiro país em endemismo avícola, especialmente na Caatinga, impondo uma responsabilidade de conservação. A observação de aves emerge como ferramenta vital para o desenvolvimento sustentável, destacando-se nas serras do sertão norte da Bahia, um corredor ecológico essencial para a biodiversidade. Apesar de estratégico para o Birdwatching, a região demanda conhecimento específico das aves locais, conectando biomas e oferecendo potencial para o ecoturismo. Este estudo busca avaliar o potencial turístico da avifauna na região serrana de Jaguarari, norte da Bahia, com base na Etnoornitologia e na Ecologia Humana em ambientes de altitudes elevadas. Identificaram-se dois promissores roteiros, como Serras de Catuni e Serra dos Morgados, catalogando diversas espécies, incluindo as ameaçadas de extinção, como Araponga e Jacu. Essas aves podem se tornar ícones para programas de conservação, contribuindo não apenas para a proteção ambiental, mas também para a economia local e a valorização das comunidades. O estudo visa promover a inclusão social no manejo sustentável, destacando a importância das aves na região e combatendo a destruição dos habitats devido a empreendimentos complexos em regiões montanhosas.
İş Başvurusunda Bulunan Engelli Bireylerin Bilişsel ve Fiziksel Düzeylerinin Yaşam Kalitelerine Etkisinin İncelenmesi
Authors: Yücel Hülya , Erarslan İbrahim
Published: December 2024

Amaç: İş başvurusunda bulunan engelli bireylerin bilişsel ve fiziksel aktivite düzeyleri iş istihdamları için önemlidir. Bu çalışmada iş başvurusunda bulunan engelli bireylerin bilişsel ve fiziksel durumlarının yaşam kalitelerine etkisinin incelenmesi amaçlandı. Gereç ve Yöntemler: Çalışmaya Mayıs-Haziran 2024 tarihleri arasında, İstanbul ili XXX ilçesinde bulunan İŞKUR’a başvuran 72 engelli birey dahil edildi. Çalışmanın verileri yüz yüze görüşme tekniği ile Sosyo-Demografik Bilgi Formu, Montreal Bilişsel Değerlendirme Ölçeği, Fiziksel Engelli Bireyler İçin Fiziksel Aktivite Ölçeği ve Dünya Sağlık Örgütü Yaşam Kalite Ölçeği kullanılarak elde edildi. Değişkenler normal dağılım göstermediğinden ilişkisel tarama için Spearman korelasyon analizi kullanıldı. Bulgular: Katılımcıların bilişsel seviyeleri ile yaşam kaliteleri arasında anlamlı bir ilişki olmadığı tespit edildi (r=0.172, p=0.15). Katılımcıların fiziksel aktivite düzeyleri ile yaşam kaliteleri arasında pozitif yönde ve zayıf bir ilişkinin olduğu (r=0.26, p=0.03) bulundu. Sonuç: Çalışmamızda, iş başvurusunda bulunan engelli bireylerin fiziksel aktivite düzeylerinin ve yaşam kalitelerinin birbiri ile pozitif yönde bir ilişkisinin olduğu sonucuna varıldı. Çalışmamız işe başvuran özel bir engelli grubunda bilişsel ve fiziksel limitasyonların yaşam kalitesine etkisini değerlendiren Ülkemizdeki ilk çalışmadır. Çalışmamızın sonucunun gelecekte yapılacak araştırmalara yol gösterici olacağı düşünülmektedir.
Avaliação de Desempenho de API Gateways para o Gerenciamento de Acessos a Microsserviços
Authors: Cargnelutti Rodrigo , Minuzzi Giulliano , Agilar Everton de Vargas , Basso Fábio Paulo , Bernardino Maicon
Published: December 2024

Este estudo desenvolve e avalia API Gateways para o controle de acessos em uma arquitetura de microsserviços. O trabalho compara a API Gateways desenvolvida e o Kong API Gateway, utilizando a ferramenta Locust para testes de desempenho com workloads de 100 e 500 usuários simultâneos. Foram analisados os endpoints Mobile e Webservice, com métricas de número de requisições, tempo de resposta e uso de recursos computacionais. Os resultados mostram que ambas as soluções são eficientes, com o Kong se destacando no uso de rede, enquanto a API Gateways desenvolvida demonstrou melhor consumo de memória. Conclui-se que uma API Gateways é fundamental para o controle de acessos e a segurança na arquitetura de microsserviços.
Especificação de Requisitos de Segurança em Firewalls de Próxima Geração: Abordagens e Desafios
Authors: Morais Tiago W. , Scherer Felipe H. , Dresch Felipe N. , Quincozes Silvio E. , Kreutz Diego , Quincozes Vagner E.
Published: December 2024

Este trabalho especifica o framework MORAIS, o qual oferece direções iniciais para auxiliar equipes de desenvolvimento na estruturação e validação de requisitos de segurança no desenvolvimento de Firewalls de Próxima Geração (NGFWs), considerando a adaptação às ameaças dinâmicas e a conformidade com regulamentações. As etapas do framework incluem Monitoramento, Otimização, Auditoria, Requisitos, Integração e Simulação, permitindo uma abordagem estruturada para enfrentar os principais desafios de desempenho, integração e conformidade. Os resultados obtidos através de uma prova de conceitos indicam que a implementação do MORAIS pode trazer melhorias contínuas, adaptabilidade e eficácia para NGFWs.
Kernel for IoT Systems Software (KISS)
Authors: Alves Luis Fernando , Amalfi Pedro , Martin Santiago , Schepke Claudio , Rodrigues Elder , Bernardino Maicon
Published: December 2024

O estudo explora a modelagem Essence, uma abordagem flexível da SEMAT para gerenciar o desenvolvimento de software. Organizada em torno de três áreas principais — Clientes, Solução e Esforço — a metodologia facilita o alinhamento de requisitos e a entrega de soluções eficientes. Por meio da aplicação em um domínio de um sistema de monitoramento ambiental, o estudo propõe como os componentes essenciais, chamados Alfas, poderiam ajudar a acompanhar o progresso e apoiar a melhoria contínua do software, destacando ainda as competências necessárias e os benefícios de transparência e flexibilidade.
Antifeministische Netzwerke in Europa: Akteure, Mechanismen und Gegenstrategien
Authors: Amberger Silja
Published: December 2024

„Räume zurückerobern“ – ein Auftrag, der vielversprechend und herausfordernd zugleich klingt: Antifeministische Netzwerke versuchen seit einigen Jahren gezielt und systematisch, die Gleichberechtigung der Geschlechter in Frage zu stellen und Rechte von Frauen einzuschränken. Diese Entwicklung gab Anlass für die Kooperationsveranstaltung des Deutschen Juristinnenbundes e.V. (djb) mit dem Verbindungsbüro des Europäischen Parlaments und der Vertretung der Europäischen Kommission, welche am 23.09.2024 im Europäischen Haus in Berlin stattfand. Es nahmen 170 Personen in Präsenz und mehr als 150 Personen via Live-Stream an der Veranstaltung teil. In einem moderierten Gespräch mit anschließender Podiumsdiskussion beleuchteten Dr. Katarina Barley, Judith Rahner, Josephine Ballon und Dr. Roya Sangi den Einfluss antifeministischer Netzwerke unter unterschiedlichen rechtlichen Gesichtspunkten und setzten sich mit Ansätzen zum Umgang mit Antifeminismus auseinander. Die Veranstaltung nahm rechtliche und rechtspolitische Instrumente in den Blick, mit denen antifeministische Netzwerke Einfluss auf den europäischen Diskurs, die Rechtsetzung und die Rechtsprechung nehmen. Im Fokus der Diskussion stand dabei vor allem der Umgang mit Hasskriminalität im Internet.
ATP-Sensitive Potassium Channel
Authors: Yang Hua-Qian , Che Shuhan , Huo Jianyi , Yang Qianqian
Published: December 2024

The aim of this chapter is to delve comprehensively into ATP-sensitive potassium (KATP) channel, which is a ubiquitous class of potassium ion channels located in the biological membrane to sense intracellular nucleotide (ATP/ADP) concentration and mediate potassium efflux in various cell types (and mitochondria), thus functions as a link between intracellular metabolic state and cell membrane excitability. This chapter mainly includes five parts: the road to the discovery of KATP channel, protein subunit composition of KATP channel, the pharmacology of KATP channel, and the physiological and pathological roles of KATP channel, with particular emphasis on pancreas, heart, vascular smooth muscles, and the nervous system.
Environmental Factors and Cyanobacteria Genotype: Implications for Toxin Production
Authors: Iasmina Moza Maria , Bianca Pavel Ana , Postolache Carmen
Published: December 2024

Starting from the well-known fact that a poor ecological status is associated with increasing phytoplankton abundance, greater proportions of cyanobacteria, and more frequent and intense toxic blooms, the main purpose of this chapter was to investigate abiotic and biotic factors influencing the ecology of Cyanobacteria populations and the expression of their toxigenic potential, by presenting results and conclusion both from field and laboratory studies found in the literature so far. A general overview of the complexity of factors is summarized at the end of the review in five scenarios about the Cyanobacteria behavior in freshwater ecosystems under different ecological statuses.
Endovascular Techniques for the Treatment of Venous Diseases
Authors: da Cruz Renó Leonardo , Araújo Cortines Laxe Renó Angélica
Published: December 2024

This chapter analyzes the use of minimally invasive endovascular techniques for the treatment of acute and chronic venous diseases, demonstrating their improved use due to the development of new materials and improved techniques. We conclude that today, we can treat everything from acute venous thrombosis, with the aim of reducing progression to chronic venous disease, to pulmonary embolism, with the aim of reducing mortality and improving quality of life. In addition, pulmonary embolism is prevented with vena cava filters that are increasingly easy to implant, and venous compressions and chronic venous occlusions are treated with stents dedicated to the venous system.
Understanding Pyroprocessing Throughput in the Context of Safeguards
Authors: Barker Eva , I. Hargreaves Abigayle , Witt Jolanna , Berry Jaylyn , Bice Leyton , Frasure Mitchell , Gannon Leo , Gundersen Christopher , Lambert Matthew , Lang Ethan , Munoz Salvador , Palmer Jaden , Shanahan Sweet , Snow Nelson , L. Pope Chad
Published: December 2024

As advanced reactors are nearing end-stage development as part of the growing effort to resolve society’s energy crisis, the interest in reprocessing used nuclear fuel is increasing. Pyroprocessing is a tested reprocessing technology requiring additional study before it may be considered for commercial viability. The Resonance Absorption Densitometry for Materials Assay Security Safeguards (RADMASS) program aims to study a non-destructive assay (NDA) method and create a safeguards model that may aid in the commercial development of pyroprocessing. Measurement uncertainties and time for input accountancy measurements are incorporated into the safeguards model, which is used to inform the development of a pyroprocessing facility model. Preliminary safeguards modeling results show that the magnitude of input accountancy uncertainty is of critical importance, with other factors vary. The initial findings from the safeguards model generated measurement averages that match what is expected for a real facility. Results from modeling assist in the understanding that as throughput size of a facility increases, the standard error of inventory difference (SEID) and inventory difference (ID) values also increase. While these results represent great progress toward the commercial viability of pyroprocessing, there is still more to be done before commercialization may proceed.
The Effect of COVID-19 Lockdown on Appendicitis Severity and Management
Authors: Rodwell Aaron , Gracias Dylan , Seth Ishith , Hewitt Lyndel
Published: December 2024

The COVID-19 pandemic placed substantial strains on healthcare systems globally causing downstream sequalae on emergency surgical conditions including acute appendicitis. The primary aims of this study were to examine rates of complicated appendicitis, conservatively managed uncomplicated appendicitis and outcomes of acute appendicitis management before, during and after the New South Wales’ COVID-19 lockdown in Australia. Retrospective analysis of patients with acute appendicitis in a NSW local health district between 4th December 2019 and 13th October 2020 was undertaken. Patients were grouped temporally into Pre-lockdown, Lockdown or Post-lockdown groups. No significant change in the rates of complicated appendicitis during the lockdown compared to periods immediately before and after the lockdown were found. Patients with complicated appendicitis tended to be older and have longer hospital stays. Conservatively treated uncomplicated appendicitis rates did not increase during the lockdown period. The findings indicate potential for lower threshold for investigation and management of suspected acute appendicitis in older people and criteria for conservative management of uncomplicated appendicitis may require revision. Analysis of pandemic surgical rates could enhance bed management planning for future disasters, ensuring optimal patient safety. Further research is required to delineate the effect of lockdowns on acute appendicitis and may inform changes to practice.
Application of Artificial Intelligence-Driven Federated Learning Based on Machine Learning and Deep Learning in Medicine
Authors: Li Luwei
Published: December 2024

Currently, artificial intelligence (AI) technology is developing rapidly. Machine learning and deep learning are algorithms in the field of AI, and their combined use in federated learning is becoming increasingly common in medical research. The emergence of federated learning technology aims to train machine learning and deep learning algorithms across multiple distributed devices or servers. Federated learning has greatly promoted the development of AI in the medical field. The core of this approach is to construct complex and accurate models by automatically learning and extracting useful features from large amounts of data from multiple data sources, thereby building models with both high accuracy and precision. The widespread adoption of federated learning is bound to lead to breakthrough advances in areas such as precision medicine, clinical decision support, new drug development, medical image recognition, medical language processing, and medical speech recognition. This chapter draws on the author’s experience in big data medical modeling and validation from multiple data sources to introduce algorithms and operational modes in the field of federated learning, offering a glimpse into the promising future of the intelligent world.
Exploring AI Applications in Essay-Based Assignments: Affordances and Risks
Authors: Alzahrani Ahmad , Zheng Ying
Published: December 2024

This study examined the feasibility of employing artificial intelligence (AI) for feedback provision on essay-based assignments in a UK Higher Education setting. Although the critical role of feedback in enhancing students’ learning experiences is widely recognised, resource limitations and large student numbers often hinder its quality and timely delivery. Through in-depth interviews with four participants from a university in the UK, this research investigated AI applications in essay evaluation, utilising data from 12 AI-generated essays and their corresponding feedback. The aims of the study are to evaluate tutors’ abilities in discerning human and AI-generated essays, as well as evaluating the quality of AI-generated feedback from their perspectives. Findings showed that assessors could detect certain characteristics consistent with AI generation and noted ethical concerns regarding deviations from academic standards. Participants also acknowledged AI’s capacity for swift feedback delivery as compared to human. The results of this study help enhance our understanding of AI’s affordances and risks in assessment and feedback, particularly in the less explored university essay assignments.
Management of Prostate Cancer Associated Disseminated Intravascular Coagulation (DIC): A Multidisciplinary and Individualized Approach
Authors: Schwartzman William , Wilson Parker , Gray Zane , Wang Jue
Published: December 2024

Disseminated intravascular coagulation (DIC) is a complex clinical syndrome characterized by systemic activation of coagulation pathways, leading to the formation of microvascular thrombi, which can result in multi-organ dysfunction and bleeding due to the consumption of coagulation factors and platelets. In patients with prostate cancer, DIC poses a significant diagnostic and management challenge due to its multifactorial etiology, overlapping clinical features with other coagulopathies, and its impact on patient outcomes. DIC often presents with non-specific symptoms that overlap with those of advanced prostate cancer and its treatments, which may lead to delays in diagnosis. While the prognosis for prostate cancer patients with DIC is generally poor, active cancer therapy, including androgen deprivation therapy (ADT), chemotherapy, and newer anticancer therapies can improve overall survival by addressing the underlying malignancy. Understanding the interplay between prostate cancer progression and hypercoagulation provides a foundation for developing individualized precision medicine strategies to prevent and manage DIC in prostate cancer patients, potentially improving outcomes in this challenging clinical scenario. Future research will continue to refine these approaches, integrating new discoveries into personalized care strategies that address both the malignancy and its hematologic complications.
Comparison of the Effect of High-Intensity Laser Therapy and Quadriceps Muscle Strengthening Exercises Using Biofeedback on Pain, Stiffness and Function of Patients with Knee Osteoarthritis: A Randomized Clinical Trial
Authors: Rahimi Maryam Sadat , Jafari-Nozad Amir Masoud , Jazebi Fatemeh
Published: December 2024

Objectives: This study aims to compare the effects of high-intensity laser therapy (HILT) and quadriceps muscle strengthening exercises using biofeedback on pain and function in patients with knee osteoarthritis (KOA). Methods: This randomized, two-group clinical trial included patients with KOA (grades II - III of the Lawrence Kellgren classification) who met the inclusion criteria. Written informed consent was obtained from participants before they were randomly allocated into one of two groups: HILT + therapeutic exercise (group A) or quadriceps muscle strengthening exercises using biofeedback + therapeutic exercise (group B). Both groups followed the same therapeutic exercise regimen during the study. Knee pain severity was evaluated using the Visual Analogue Scale (VAS), and functional disability was assessed with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire before the intervention. For group A, HILT was performed using a BTL-6000 HIL device (wavelength 1064 nm, maximum power 12 W) following the manufacturer-recommended protocol. A pain relief program (10 W, 120 J/cm²) was administered for 120 seconds per session over ten sessions. Treatment protocol, laser positioning, and session duration were standardized. Two follow-up assessments (immediately and one-month post-intervention) were conducted to evaluate outcomes based on the VAS and WOMAC scores. Results: The study included 40 participants with KOA, divided evenly between the two groups (20 in each). The average age of the participants was 59.34 ± 6.92 years. High-intensity laser therapy group (group A): Visual analogue scale pain scores decreased significantly immediately after and one month post-intervention compared to baseline (P < 0.01). However, the VAS score one month after the intervention showed no significant difference compared to the immediate post-intervention score (P = 0.59). Biofeedback group (group B): VAS pain scores also decreased significantly both immediately after and one month post-intervention compared to baseline (P < 0.05). The difference in VAS pain reduction between the two groups was significant, with the HILT group showing greater improvement immediately after the intervention and one month later (P = 0.007). Conclusions: The study findings suggest that both quadriceps muscle strengthening exercises using biofeedback and HILT effectively reduce pain in KOA patients. However, HILT demonstrated superior efficacy compared to biofeedback exercises. These results support the use of HILT as a noninvasive therapeutic modality for KOA, particularly for patients with a higher risk of surgery due to preexisting comorbidities.