bluuebunny/crossref_metadata_2025 huggingface dataset:
Kesesatan Berpikir dalam Konteks Hukum dan Masyarakat: Studi Kasus Politik Elektoral dan Budaya Media Sosial di Indonesia
Authors: Sebastian Tanius
Published: December 2019

This article investigates the phenomena of electoral politics and culture of social media in the context of Indonesian law and society through a case study of Jakarta Gubernatorial Election in 2017. The main argument of this article is that the connection between electoral politics and culture of social media shows a fallacious logical thinking in the form of bias and ad populum reasoning. Those two forms of fallacy refer to sectarian politics and ideological polarization. In analyzing the fallacious thinking in some events of the 2017 Jakarta Gubernatorial Election, this article also shows how emotion, anxiety, and hate operate within the reasoning of the relation of the Indonesian state and society. This article primarily aims at identifying the argumentative situation in the case of the 2017 Jakarta Gubernatorial Election, which contains the fallacious thinking. In the end, the ultimate aim is to evaluate an implication that stems from that identification for an adequate conception of legal reasoning in the Indonesian context.
Kosakata Musik Sebagai Ranah Sumber Ungkapan Metaforis
Authors: Kusumaningtyas Adityarini , Darmojuwono Setiawati
Published: December 2019

In Indonesian, music vocabulary is not only used to describe music but also used to express various non-musical concepts. That means music vocabulary has the potential to occupy the source domain in metaphorical mapping. The study aims at describing the vocabulary of music as the source domain of metaphorical expressions in Indonesian and explaining the relation of metaphorical meanings to the music field. The study was qualitative research. The data of the study was collected from the corpus of Indonesian in the Sketch Engine. The data was Indonesian sentences having the vocabulary of nada, melodi, harmoni, and dinamika in which the contexts of sentences were used to talk about anything in non-music field. The results of the study show that the vocabulary of music in Indonesian causes the metaphor of “LIFE IS MUSIC”. The use of music vocabulary as a source domain is mainly related to the characteristics of musical vocabulary concepts that underlie the formation of metaphorical expressions in Indonesian.
PERTARUNGAN JURNALISME DAN SASTRA DALAM MENGUAK KEBENARAN
Authors: Wahyuni Dessy
Published: December 2019

The existence of facts in journalism can be manipulated, while the truth settles in literature. Although both types of writing, namely news texts, which contain facts, and literary texts, which contain fiction, depart from the same reality, the estuary of the truth in it can be different because it is seen from different perspectives and interests. For these various interests, silencing in journalism often occurs. Facts are circumcised, overhauled, and arranged in such a way as to produce new facts. Meanwhile, in literature, facts are packaged using imagination to disguise the truth as if it did not happen. For this reason, using a functional systemic linguistic approach, the authors uncover various linguistic considerations built by Seno Gumira Ajidarma (SGA) in reducing news in Jakarta Jakarta to fulfill certain interests. Then, the writers also dismantled the formation of meaning behind each text in SGA's "Saksi Mata", which contained elements of resistance in literature, by using Derrida's deconstruction. The result of the study shows that the same facts can be stated in a variety of different and subjective ways. In this case, literary work is an effective tool to voice the truth.

 
WACANA NASIONALISME KRITIS DALAM MUSIK BANYUWANGIAN PADA MASA ORDE BARU
Authors: Tallapessy Albert , Setiawan Ikwan , Sariono Agus , Suwargono Eko
Published: December 2019

This article deals with the representation of critical nationalism discourse in Banyuwangian music in the New Order era. By juxtaposing representation and hegemony theory which emphasizes textual-contextual reading, we will analyze the constructions of local metaphors we assume supporting the establishment of nationalism. Such constructions intertwined with the mobilization of the uniqueness of local cultures that contributed to establishing the national culture through which nationalism got its “nutrition”. However, some songwriters constructed critical nationalism by representing unique metaphors related to the characteristics of subaltern subjects that in the midst of their problems songwriters still have, in their silence, critical view toward the ruling faction, without negating their responsibility to guard the nation. The representation of critical nationalism using local metaphors is a critique of the social and economic problems caused by the injustice of development programs as well as a creative strategy to negotiate Using cultures in the midst of modernity.
Yöneticilerin Gözünden Türkiye’de Çevrimiçi Uzaktan Lisansüstü Eğitim
Authors: İZMİRLİ Serkan , ŞAHİN İZMİRLİ Özden , ÇANKAYA Serkan
Published: December 2019

Bu çalışmada Türkiye’deki
çevrimiçi uzaktan lisansüstü eğitim (YL ve DR) hakkında yöneticilik deneyimi
olan uzmanların görüşleri incelenmiştir. Çalışmada Türkiye’de uzaktan tezli
YL’nin neden yaygın olmadığı ve DR programlarının neden bulunmadığı
sorgulanmıştır. Nitel olarak desenlenen araştırmada veriler, açık uçlu soru
formu ile çevrimiçi olarak toplanmıştır. Araştırmanın katılımcılarını uzaktan
öğretimde yöneticilik deneyimi olan 12 öğretim elemanı oluşturmuştur.
Araştırmadan elde edilen nitel veriler içerik analizi yöntemi ile analiz
edilmiştir. Araştırma bulgularına göre, uzaktan öğretim yöneticileri,
Türkiye’de uzaktan tezli YL’nin yaygın olmaması ve DR’nin olmamasının nedenleri
arasında mevzuatın olmaması, uzaktan eğitime karşı negatif algı gibi çeşitli
sorunları ifade etmişlerdir. Araştırmaya katılan yöneticilerin büyük bir
çoğunluğu Türkiye’de tezli YL ve DR’nin uzaktan verilebileceğini ifade
etmişlerdir.
Karadeniz’in Türkiye için Kıyısal Jeopolitik Açıdan Önemi
Authors: Demir Konur Alp
Published: December 2019

Kıyısal jeopolitik, okyanus, deniz, göl, boğaz, delta ve nehir gibi su kütlelerinin bir ülkenin jeopolitiğine stratejik açıdan katkı yapmasını açıklayan bir kavramdır. Bu kavram çerçevesinde ve aynı eksen etrafında değerlendirildiği takdirde bir iç deniz olarak nitelendirilebilecek Karadeniz’in coğrafi konumu ile Türkiye’nin Avrupa ile Asya’yı birbirine bağlayan bir noktada konumlanması Karadeniz’i hem Türkiye hem de Avrupa ve Asya için önemli bir konuma yükseltmektedir. Bu bağlamda Karadeniz’in Türkiye için coğrafya, ekonomi, siyaset ve güvenlik unsurları açısından incelenmesi gereken bir değeri ortaya çıkmaktadır. Karadeniz’in uluslararası ilişkiler bağlamında siyaset, ekonomi ve güvenlik üçlemesinin kilit noktasında durması bu bölgeye olan ilgiyi arttırmaktadır. Bu çalışmada Türkiye’nin Karadeniz’de en uzun kıyı şeridine sahip olması bağlamında küresel siyaset ve uluslararası güvenlik konularındaki üstünlüğüne vurgu yapılacak, Karadeniz’in küresel siyasetteki önemi ve yeri değerlendirmeye alınacak, uluslararası güvenlik konularında Türkiye’nin yeterliliğini güçlendiren Karadeniz’in jeopolitik konumu incelenecektir. Bununla birlikte, çalışmada farklı unsurların Karadeniz üzerindeki hâkimiyet kurma çabaları incelenecektir. İlgili çabalar küresel yapılanmalar ve anlaşmazlıklar üzerinden gerçekleştirilmeye çalışılacaktır. Çalışmanın nihai amacı Karadeniz’in Türkiye için öneminin kıyısal jeopolitik konumu açısından değerlendirilmesidir.
Investigation of the Collimator Effect on the 3’’x3’’ NaI(TI) Detector System by the FLUKA code
Authors: KULUÖZTÜRK Zehra Nur , DEMİR Nilgün
Published: December 2019

The efficiency of the
3’’x3’’ NaI(TI) detector and gamma attenuation calculations were investigated
under the different collimation parameters. In this purpose, photon beams with
511 and 1332 keV energy were collimated by using Pb collimator with different
diameters. This system was defined by the FLUKA Monte Carlo code; the detector
efficiency and gamma attenuation coefficients were simulated.
Analisis Perbandingan Kinerja Pengkodean Kanal Non-Return-to-Zero (NRZ) dan Return-to-Zero (RZ) pada Rancangan Jaringan Long-haul Dense Wavelength Division Multiplexing (DWDM)
Authors: Pratama Olivian Bagas , Isnawati Anggun Fitrian , Zulherman Dodi
Published: December 2019

Abstrak Perkembangan jangkauan dan penggunaan internet mendorong pengembangan penyediaan layanan dengan transmisi data yang cepat dan kapasitas yang besar seperti layanan berbasis serat optik. Jaringan long-haul DWDM sebagai teknologi multipleksing sangat mendukung proses transmisi optik jarak jauh. Performa media transmisi long-haul DWDM membutuhkan teknik pengkodean kanal yang dapat diimplementasikan pada sisi pengirim agar diperoleh sistem yang efisien dalam hal bandwidth transmisi. Dalam komunikasi serat optik terdapat beberapa jenis teknik pengkodean kanal yang umum digunakan seperti non-return-to-zero (NRZ) dan return-to-zero (RZ). Penelitian ini bertujuan untuk membandingkan kinerja rancangan sistem dengan variasi teknik pengkodean dengan memberikan variasi daya pancar laser sebesar 0, 2, 4, 6, dan 8 dBm dan variasi jarak sebesar 200, 400, 600, 800, dan 1000 km. Rancangan sistem menggunakan modulasi eksternal dan NRZ atau RZ pada sisi transmitter, serat optik dan penguat EDFA pada media transmisi, dan detektor optik pada sisi receiver. Berdasarkan hasil penelitian, tidak semua kanal sesuai dengan hasil Q-factor dan BER berdasarkan standar ITU-T, namun jenis pengkodean kanal NRZ lebih baik digunakan pada jenis jaringan long-haul DWDM. Abstract The increasing of coverage area and demand for internet services are both drive the development of providing services with high bitrate transmission and gigantic capacity, such as fiber optic communication. Long-haul DWDM network as a multiplexing technology is very supportive in the long-distance optical transmission link requiring channel coding which can be implemented in transmitter. There are various types of channel coding used in optical fiber communication, such as non-return-to-zero and return-to-zero. The aims of this work are to compare the system performance with different channel coding in long-haul link using variations of optical power launch with value 0, 2, 4, 6, and 8 dBm and variations of length of link with value 200, 400, 600, 800, and 1000 km. The design system uses external modulation and NRZ or RZ on the transmitter, optical Fiber with EDFA amplifier on the optical transmission, and optical detector on the receiver. Based on the results, there are several channels with the Q-factor and BER that do not meet the ITU standards. In addition, the NRZ channel coding is better used in the long-haul DWDM link.
Borsa İstanbul’un gelişmiş ve gelişmekte olan ülke borsaları ile eşbütünleşme analizi
Authors: GÜZEL Fatih , Uçan Okyay , Acar Melek
Published: December 2019

Bu çalışmanın amacı, Türkiye
ile gelişen ve gelişmekte olan ülkeler arasındaki ekonomik etkileşimi
incelemektir. Türkiye başta olmak üzere 10 adet gelişmekte olan ülke ve sekiz
adet gelişmiş ülke borsası analize dahil edilmiştir. Veri seti Ocak 2010 -
Aralık 2017 aylık borsa endeks değerlerinden oluşmaktadır. Sonuç olarak,
Türkiye’nin hem gelişmiş hem de gelişmekte olan seçilmiş ülkelerin borsaları
ile eşbütünleşik olduğu, bununla birlikte gelişmekte olan seçilmiş ülke
grubunun kendi aralarında eşbütünleşik, ancak seçilmiş gelişmiş ülke grubunun
kendi aralarında eşbütünleşik olmadığı tespit edilmiştir. Dolayısıyla,
eşbütünleşik yapıları nedeniyle, gelişmekte olan ülke borsalarının modern
portföy teorisi çerçevesinde birbirlerinin alternatifi olamayacağı bulgusuna
ulaşılmıştır. Bu sonuca göre, uzun vadede gelişmekte olan ülke borsaları
arasında risk dağıtımı yapmak mümkün değildir. Gelişmiş ülke borsaları ise,
grup içerisinde entegre olmamaları nedeniyle, yatırım alternatifi olarak
birbirlerinin ikamesi konumundadır.
Pilotlar üzerinde iş tatmini ve motivasyon ölçme aracının geliştirilmesi: Geçerlilik ve güvenilirlik çalışması
Authors: İNAN Tüzün Tolga
Published: December 2019

Pilotlar üzerindeki iş
tatmini ve motivasyonu ölçmek amacıyla yapılan geçerlilik ve güvenilirlik
çalışmasının giriş bölümünde, geçerlilik ve güvenilirlik kavramları
incelenmiştir. Materyal ve metod bölümünde; kayşat planı (scree plot),
özdeğerlerin 1’den büyük olma kuralı ve toplam varyansın açıklayıcılık yüzdesi
ölçütleri kullanılmıştır. Anketin güvenilirliği iç tutarlılık ve sınıflararası
tutarlılık kavramları ile açıklanmıştır. Anketin geçerliliği bölümünde ise
geçerlilik/açıklayıcı faktör analizi ile birlikte rotasyonlu bileşenler matrisi
(faktör yükleri), faktörlerin tanımlayıcı istatistikleri ve korelasyon matrisi
ile faktörler arasındaki ilişki tablo ve şekiller ile ifade edilmiştir. Son
bölüm sonuç ve önerilerde ise 15 ayrı faktörün birbirleriyle korelasyon analiz
edilerek yorumlanmış ve ilerideki çalışmalar için öneride bulunulmuştur.
Conceptual Approaches to the Formation of Architecture of Documents of Strategic Planning in Russia
Authors: Smirnova O. O. , Bocharova L. K. , Belyaevskaya-Plotnik L. A. , Bogdanova Ju. N.
Published: December 2019

Purpose: of the article is to prepare evidence-based proposals for the formation of document architecture, strategic planning, fundamental for modern needs and ensuring the integrity of the strategy for all levels of government and business, as well as to ensure the implementation of the principles of unity, integrity, continuity, continuity and delineation of powers in organizing and system functioning, strategic planning as part of a single management cycle.

In the framework of the task of creating the architecture of documents, strategic planning also solves the important task of linking issues of socioeconomic development and ensuring national security, and as a result – improving the efficiency of public administration, ensuring coherence and coordination of the country's strategic priorities.

Methods: the main method of work is the disclosure of the principles of strategic planning. The architecture of strategic planning documents under development is based on the disclosure of regulatory acts of the Federal Law dated 28.06.2014 N 172-FZ “On Strategic Planning in the Russian Federation”.

Results: the absence of normatively fixed principles and a system for ensuring strategic planning, as well as the procedure for implementing strategic planning, leads to inconsistency of the approved strategies and forecasting, the development of new documents and studies in the Federal Law “On Strategic Planning in the Russian Federation” and other violations of the systematic approach. In this regard, it is necessary to determine the architecture of the system of strategic planning documents developed as part of the target definition, forecasting, planning and programming.

Conclusions and Relevance: the architecture of strategic planning documents proposed in the article is based on the creation of a three-level document system with a central place in it the National Security Strategy of the Russian Federation as the main document of strategic goalsetting. In accordance with Federal Law N 172-FZ, the level of forecasting, target definition, planning and programming allows you to add a conceptual level that ensures the quality of the overall ideological superstructure, which should provide an idea of what kind of character for the state and its position in the world the strategic planning system should provide. Taking into account the task of minimizing amendments and clarifications to the Federal Law “On Strategic Planning in the Russian Federation”, the proposed changes are more in the nature of clarifying the provisions of this law.

The architecture of the documents built in this way will allow implementing and, if necessary, further detailing the principles of strategic planning defined by law 172-FZ and, above all, the principles of continuity, balance of the strategic planning system.
Digital Transformation Policy in Japan: the Case of Artificial Intelligence
Authors: Kostyukova K. S.
Published: December 2019

Purpose:this article includes the review of the Japanese policy on the national economy Digital Transformation, using the case of implementation of artificial intelligence for production and services, description and analysis of the current results, as well as identification of obstacles to achieve the expected results.

Methods:the article is based on the analysis of scientific and analytical materials to the problem of research. The factual basis is the framework documents of the Cabinet of Japan, media, reports on research conducted by Japanese research institutes.

Results:the article provides a brief review and analysis of the Japanese public policy of the development of AI technology, summarizes the interim results of the measures taken, identifies problematic factors that prevent the achievement of the expected results. The hypothesis is put forward about the insufficiency of government efforts to monitor and analyze the activities already implemented, the lack of practice of taking into account failures in the formation of new programs and projects. Recently, significant attention to the development of AI technology is paid in Russia. In 2019, Russian President Vladimir Putin approved the "National strategy for the development of AI until 2030". It is expected that the using of digital technologies, will increase the competitiveness of the national economy, improve the welfare of society. In this regard, the study of Japan's experience as one of the technological leaders in the development and using of digital transformation, is especially important.

Conclusions and Relevance:To solve the current socio-economic problems, Japan government relies on the development of the advanced technologies. At the same time, the government continues to develop measures to stimulate the cooperation of the academic and industrial sectors to conduct joint R&D on priority technologies. However, due to the "closed" nature of Japanese corporations and the relative independence of government plans in determining the technological priorities development, the corporate sector is reluctant to follow government recommendations on the using new technologies in management and production processes, as well as joint projects with the academic sector are not large-scale and are rather formal. This situation indicates the continuing unpreparedness of key NIS participants for the perception of the advanced technologies and digital transformation.
Methodology and Practical Tools for Digital Transformation of High-tech Enterprises
Authors: Batova M. M. , Baranova I. V. , Mayorov S. V. , Korobchenko O. V.
Published: December 2019

Purpose: the aim of the article is to develop a methodology and practical tools for effective digital transformation of high-tech enterprises. To achieve this goal, a concept of enterprise transformation by means of innovative modernization, affecting changes in products, technological operations and organizational and production structures, was developed. For this, a number of tasks were solved, including the development of original economic and mathematical models that describe the change in the functional business strategies of a high-tech enterprise; selection and formalization of model variables; development of organizational design methods for flexible robotic structures and models for determining the parameters of flexibility and productivity of a robotic structure; software development of digital transformation processes.

Methods: in preparing the article, methods of systems theory, project management of an innovative focus, mathematical modeling and a number of other methods were used.

Results: a set of information systems for decision support in the areas of design and economic activities of a high-tech enterprise has been developed. The design of such systems was due to a number of circumstances. Firstly, the need to transform traditional information technologies used in the practice of a high-tech enterprise into digital information technologies. Secondly, the need for a high-tech enterprise in original applied software applications that provide solutions to innovative and economic problems, taking into account the specifics of the enterprise. To do this, an analysis was performed and models of data collection and storage were proposed for solving the problems of information support of the economic activity of a high-tech enterprise. The possibility of using a consistent data model in organizing the management of receivables and payables is shown. Cross-platform software was developed for the support system for decisions made by a high-tech enterprise, and a convenient user interface was implemented.

Conclusions and Relevance: the study showed that it is advisable to create information systems as hierarchical structures covering the strategic, tactical and operational levels of management. In order to bring the automation level of the control and production subsystems into conformity, industrial robotics must be integrated into the created production links.
Intramuscular oxytocin 10 units versus intravenous methylergometrine 0.2 mg in active management of third stage of labour for prevention of postpartum haemorrhage: a comparative study
Authors: Narayana Divya , Pathak B. , Khurana Abha , Kohli Uttara Aiyer
Published: December 2019

Background: To compare the effectiveness of 10 IU of oxytocin IM with 0.2 mg methyl ergometrine IV in the prevention of post-partum hemorrhage when used as a part of active management of third stage of labour. This study aims to compare their influence on duration of the third stage of labour, the amount of blood loss during the third stage of labour and the immediate post-partum period and side effects of the drugs if any.Methods: The study was conducted in a tertiary care teaching hospital. 200 women, who underwent normal delivery with or without episiotomy, were enrolled and were randomly distributed into two groups. 100 women received 10 IU of intramuscular Oxytocin and 100 women received intravenous 0.2 mg of methyl ergometrine. Women of both the groups were given the medication after delivery of anterior shoulder of the baby. Comparison done between percentages fall in Hb from before delivery to 24 hours after delivery, need for additional uterotonic agents, need for blood transfusion, duration of third stage of labour and any side effects including retained placenta and need for manual removal of placenta.Results: Intravenous methylergometrine was observed to be equally effective as intramuscular oxytocin in prevention of post-partum hemorrhage. There was no difference in the duration of third stage of labour, amount of blood loss, need for additional uterotonic agents, and need for blood transfusion in both the groups. There was no significant side effect in both the groups.Conclusions: Intramuscular oxytocin is as efficacious as Intravenous methylergometrine in the prevention of postpartum hemorrhage with no side effects.
Is Ibn Sina’s Theory of Time Compatible with McTaggart’s B-Series?
Authors: BİLGİLİ Hanife
Published: December 2019

Ibn Sina, indubitably one of the most essential
philosophers of Islamic Philosophy, constructed a new account of time
independently of Aristotle’s system, despite the major Aristotelian impact on
his time. Whilst doing this in his book Kitab
Al-Shifa, Ibn Sina also gave a proof for the reality of time based on
certain notions such as motion, speed, spatial magnitude, and the capacity he
calls “imkan” which is a divisible
magnitude, possessing before and after essentially; and how “time” is required
in order for these notions to gain meaning.The question concerning the reality of time has
attracted great attention from contemporary philosophers as well. J. Ellis
McTaggart argued time to be an illusion in his highly controversial yet
influential article “The Unreality of Time”. In this article and in his book The Nature of Existence McTaggart
claimed that time is unreal on the basis that our descriptions of time are
either circular, contradictory or insufficient. McTaggart constructed his
disproof on two different ways to cite positions in time; one being the
“A-series”, which identifies time as past, present and future moments, and the
other being the “B-series”, which basically identifies time as earlier and
later moments.This study aims at answering the question whether the
temporal system presented by Ibn Sina is compatible with McTaggart’s B-theory
of time or not.

Keywords: Ibn Sina, Time, Spatial Magnitude, Imkan, Motion, McTaggart, B-series
The method of strengtheningcharacter education values for students in industrial revolution 4.0 era
Authors: Ifadah Luluk
Published: December 2019

This study aims at providing an understanding of the Method of Strengthening the character education value for students in the Industrial revolution 4.0 era. In writing this study seeks to present methods that are relevant for strengthening the value of character education in students in Industrial revolution 4.0 era. The results showed that the method of strengthening the value of character education for students in the Industrial Revolution 4.0 era included: a) Exemplary Method, b) Pilot Method, c) Habituation Method, d) Repetition Method, e) Training Method, f) Motivation Method. The challenges are the readiness of educational institutions and educational resources, the readiness of families, the still weak control and support of elements of society, and the shift in the community's paradigm from productivity to consumptive. Then opportunities that can be exploited are self-development faster, opportunities to become innovators in every field of expertise, students from all walks of life have the same opportunity in strengthening competitiveness in the global era.
Fragments of LINE-1 retrotransposons flanked by inverted telomeric repeats are present in the bovine genome. Homology with human LINE-1 elements.
Authors: Płucienniczak G , Płucienniczak A
Published: December 2019

In the bovine genome we found two intrachromosomal DNA fragments flanked by inverted telomeric repeats (GenBank Accession Nos. AF136741 and AF136742). The internal parts of the fragments are homologous exclusively to the human sequences and to the consensus sequence of the L1MC4 subfamily of LINE-1 retrotransposons which are widespread among mammalian genomes. We found that distribution of homologous human sequences within our fragments is not random, reflecting a complicated pattern of insertion mechanisms of and maintenance of retrotransposons in mammalian genomes. One of the possible explanations of the origin of LINE-1 truncated elements flanked by inverted telomeric repeats in the bovine genome is that extrachromosomal DNA fragments may be modified by telomerase and subsequently, transferred into chromosomal DNA.
Extraribosomal function of the acidic ribosomal P1-protein YP1alpha from Saccharomyces cerevisiae.
Authors: Tchórzewski M , Boldyreff B , Grankowski N
Published: December 2019

The yeast acidic ribosomal P-proteins YP1alpha, YP1beta, YP2alpha and YP2beta were studied for a possible transactivation potential beside their ribosomal function. The fusions of P-proteins with the GAL4 DNA-binding domain were assayed toward their transcriptional activity with the aid of reporter genes in yeast. Two of the P-proteins, YP1alpha and YP1beta, exhibited transactivation potential, however, only YP1alpha can be regarded as a potent transactivator. This protein was able to transactivate a reporter gene associated with two distinct promoter systems, GAL1 or CYC1. Additionally, truncated proteins of YP1alpha and YP1beta were analyzed. The N-terminal part of YP1alpha fused to GAL4-BD showed transactivation potential but the C-terminal part did not. Our results suggest a putative extraribosomal function for these ribosomal proteins which consequently may be classified as "moonlighting" proteins.
SDS/PAGE characteristics of protein kinases tightly associated with chick embryo brain ribosomes.
Authors: Sanecka-Obacz M
Published: December 2019

Protein kinases tightly associated with chick embryo brain ribosomes washed with Triton X-100 and KCl were characterized by their ability to phosphorylate ribosomes and two exogenous substrates, histone IIA and casein. c-AMP-dependent kinase (PKA) and casein kinases (CK1, CK2) were examined in the presence of specific modulators by SDS/PAGE followed by renaturation in gel assay according to Kameshita & Fujisawa (Anal. Biochem. 1989, 183, 139-143). Basing on these data it can be presumed that PKA activity increases, but the levels of CK2 and CK1 decrease during chick embryo development.
Molecular modeling of the oxytocin receptor/bioligand interactions.
Authors: Politowska E , Czaplewski C , Ciarkowski J
Published: December 2019

Oxytocin is a nonapeptide hormone (CYIQNCPLG-NH2, OT), controlling labor and lactation in mammalian females, via interactions with specific cellular membrane receptors (OTRs). The native hormone is cyclized via a 1-6 disulfide and its receptor belongs to the GTP-binding (G) protein-coupled receptor (GPCR) family, also known as heptahelical transmembrane (7TM) or serpentine receptors. Using a technique combining multiple sequence alignments with available experimental constraints, a reliable OTR model was built. Subsequently, the OTR complexes with a selective agonist [Thr4,Gly7]OT, a selective cyclohexapeptide antagonist L-366,948 and oxytocin itself were modeled and relaxed using a constrained simulated annealing (CSA) protocol. All three ligands seem to prefer similar modes of binding to the receptor, manifested by repeating receptor residues which directly interact with the ligands. Those involved in the three complexes are putative helices: TM3: R113, K116, Q119, M123; TM4: Q171, and TM5: I201 and T205. Most of them are the equivalent residues/positions to those found in our earlier studies, regarding related vasopressin V2 receptor/bioligand interactions.
Inhibition of plasminogen activator inhibitor release in endothelial cell cultures by antisense oligodeoxyribonucleotides with a 5'-end lipophilic modification.
Authors: Kobylańska A , Pluskota E , Swiatkowska M , Wójcik M , Cierniewska-Cieślak A , Krakowiak A , Boczkowska M , Pawłowska Z , Okruszek A , Koziołkiewicz M , Cierniewski C S , Stec W J
Published: December 2019

A series of conjugates containing residues of lipophilic alcohols covalently bound to 5' end of oligodeoxyribonucleotides targeted against human plasminogen activator inhibitor (PAI-1) mRNA was synthesized via the oxathiaphospholane approach. The highest anti-PAI-1 activity in EA.hy 926 endothelial cell cultures was found for conjugates containing menthyl or heptadecanyl groups linked with an oligonucleotide complementary to a segment of human PAI-1 mRNA. The phosphodiester antisense oligonucleotides, which otherwise exhibit only limited anti-PAI-1 activity, were found to be more active than phosphorothioate oligonucleotides when conjugated to lipophilic alcohol residues. For menthyl conjugates an evidence of antisense mechanism of inhibition was found.
Interferon gamma bound to endothelial cells is phosphorylated by ecto-protein kinases.
Authors: Al-Nedawi K N , Pawłowska Z , Cierniewski C S
Published: December 2019

The presence of protein kinase activity and its phosphorylated products has been demonstrated on the outer surface of the plasma membrane of endothelial cells. Extracellular phosphorylation was detected by incubation of primary endothelial cells (HUVEC's) and endothelial cell line EA.hy 926 with [gamma-32P]ATP. The reaction products were subjected to SDS/PAGE, autoradiography and scanning densitometry. Under the experimental conditions, five proteins with apparent molecular masses of 19, 23, 55, 88, and 110 kDa were prominently phosphorylated in both types of cells. Phosphorylation of the 19 kDa protein was the most rapid reaching maximum after 60 s and then the protein became dephosphorylated. Ecto-protein kinases responsible for the surface labeling of membrane proteins were characterized by using (a) protein kinase C inhibitors: K-252b, chelerythrine chloride, and [Ala113] myelin basic protein (104-118), (b) protein kinase A inhibitor Kemptide 8334, and (c) casein kinase II inhibitor 5,6-dichloro-1-beta-D-ribofuranosyl benzimidazole (DRB). Stimulation of endothelial cells with tumor necrosis factor alpha (TNF alpha) and interferon gamma (IFN gamma) is associated with 20-80% reduction of extracellular phosphorylation of all membrane proteins. IFN gamma bound to membrane receptors becomes rapidly phosphorylated. Only in the case of IFN gamma it was associated with the appearance of a strongly phosphorylated band of 17 kDa corresponding to IFN gamma itself. Phosphorylation of this 17 kDa exogenous substrate was prevented by an ecto-kinase inhibitor K-252b. The existence of ecto-phosphoprotein phosphatase activity in endothelial cells was evidenced by testing the effect of microcystin LR--a membrane impermeable reagent that inhibits both PP-1 and PP-2a phosphoprotein phosphatases. The extent of phosphorylation of 19 kDa and 110 kDa phosphoproteins significantly increased in the presence of microcystin. Our results suggest the presence of at least two ecto-kinase activities on endothelial cells that may play a significant role(s) in the regulation of cytokines function.
RT-PCR and Northern blot analysis in search for a putative Paramecium beta-adrenergic receptor.
Authors: Płatek A , Wiejak J , Wyroba E
Published: December 2019

RT-PCR and Northern blot analysis were performed in order to search for a putative beta-adrenergic receptor (beta-AR) in Paramecium using several beta2-adrenergic-specific molecular probes. Under strictly defined RT-PCR conditions DNA species of expected molecular size about 360 bp were generated with the primers corresponding to the universal mammalian beta2-AR sequence tagged sites (located within the 4th and the 6th transmembrane regions of the receptor). This RT-PCR product hybridized in Southern blot analysis with the oligonucleotide probe designed to the highly conservative beta2-AR region involved in G-proteins interaction and located within the amplified region. Northern hybridization was performed on Paramecium total RNA and mRNA with human beta2-AR cDNA and two oligonucleotide probes: the first included Phe 290 involved in agonist binding (Strader et al., 1995) and the second was the backward RT-PCR primer. All these probes revealed the presence of about 2 kb mRNA which is consistent with the size of beta2-AR transcripts found in higher eukaryotes.
Cytostatic and cytotoxic effects of (E)-2'-deoxy-2'-(fluoromethylene)-cytidine on a solid tumor and a leukemia cell line.
Authors: Grie P , Koronkiewicz M , Skierski J S
Published: December 2019

(E)-2'-deoxy-2'-(fluoromethylene)-cytidine (FMdC), a deoxycytidine analog displaying a very high toxicity toward a variety of solid tumor cell lines and xenografts, is activated intracellularly by deoxycytidine kinase (dCK). We have compared cytotoxicity of FMdC towards a human promyeolocytic leukemia line HL-60 and a human colorectal carcinoma line COLO-205. Despite dCK activity being by far the highest in cells of lymphoid origin, the effects of FMdC were detectable at the lowest drug concentration only in a solid tumor cell line, and at higher concentrations they were qualitatively similar in the two tumor lines (increased cell protein content, cell cycle block and apoptosis). Apparently, low dCK activity in solid tumor cells sufficiently activates FMdC to yield cytotoxic effects, while high dCK activity in leukemia cells does not increase its cytotoxicity.
Temperature-dependent regulatory mechanism of larval development of the wax moth (Galleria mellonella).
Authors: Cymborowski B
Published: December 2019

The mechanisms underlying larval diapause in the wax moth (Galleria mellonella) is one of the most throughly studied aspects. At the low temperature of 18 degrees C, the last instar larvae did not pupate but transferred to 30 degrees C they initiated development and pupation in a circadian manner. Different types of surgical manipulations including head-ligation, nerve cord-severance, implantation of the brain, prothoracic glands, accompanied with ecdysteroid titre measurements indicated that diapausing arrest of larval development at 18 degrees C might be due to the nervous inhibition of their prothoracic glands.
THE STRATEGY OF PREVENTING RADICALISM THROUGH REINFORCEMENT OF THE MOSQUE TA’MIR MANAGEMENT BASED ON ASWAJA ANNAHDLIYAH
Authors: Ibda Hamidulloh , Khaq Ziaul
Published: December 2019

This article’s aim is to discuss the strategies of radicalism preventing in mosques through strengthening Aswaja Annahdliyah’s Islamic-based of mosque takmir management that is tolerant, moderate, and upholds the Islamic principle of Rahmatan Lil-alamin. This field research uses descriptive qualitative method. Data collection was obtained from interviews and observations. The results of the study mentioned that from 104 mosques in Kandangan Subdistrict, Temanggung Regency, only 96 mosques had been noted  in the Nahdlatul Ulama Mosque Takmir Institute (LTM NU), while 8 other mosques had been not. After the research was carried out, four mosques were joined and had become members of the NU LTM and implemented the takmir management of the Aswaja Annahdliyah based mosque. There are seven strategies carried out, namely; (1) strengthening management of the ideals (management of the physical building of the mosque), imarah (management of  the activities of the mosque), and riayah (management of mosque hygiene), (2) forming LTM NU at the sub-district and village level, (3) forming  management of mosques takmir by involving all elements, (4) making syllabus/ curriculum for worship timetable, education and ritual activities, (5) giving tasks to takmir to maximize mosque functions, (6) strengthening administration  management and symbolizing mosques, (7) strengthening social economic empowerment in mosques. The strategy of strengthening the takmir of mosques management has been aligned with Talcott Parsons’ structural functionalism theory with schemes adaptation, goal attainment, integration, and latency (AGIL). There are challenges and opportunities that faced. In the internal aspects, namely limited access to the city center, low human resources, and lack of comprehensive knowledge about the management of takmir of mosque External aspects, namely the existence of four mosques still controlled by radical Islamic groups, and often there are religious studies in mosques from radical groups.
Jakie oblicza glottodydaktyki polonistycznej? Różnorodność i współzależność
Authors: Dembowska-Wosik Iwona
Published: December 2019

Celem artykułu jest omówienie zawartości tekstów opublikowanych w niniejszym numerze czasopisma. Autorka pokrótce omawia wszystkie artykuły, w kolejności, w której występują, wskazując na wspólne wątki nie tylko w poszczególnych sekcjach, ale także pomiędzy tekstami o pozornie odległej tematyce.
Wymowa polska jako obca. Rozwiązywanie trudności artykulacyjnych w grupie międzynarodowej na rocznym kursie przygotowawczym
Authors: Majewska-Tworek Anna
Published: December 2019

Niniejszy tekst dotyczy pracy nad wymową polską jako obcą w grupie międzynarodowej podczas Rocznego Kursu Przygotowawczego w Szkole Języka Polskiego i Kultury dla Cudzoziemców we Wrocławiu. Porusza problem badania trudności artykulacyjnych, opisu wymowy studenta oraz doskonalenia jego sprawności w zakresie wymowy. Formułuje także ogólne wnioski dotyczące planowania zadań fonetycznych dla cudzoziemców.
TOC logical branch as a tool in teaching Polish as a foreign/second/heritage language to children
Authors: Smoleń-Wawrzusiszyn Magdalena
Published: December 2019

This article is devoted to the presentation of the author`s solutions in adapting one of the TOC thought tools to teaching Polish as a foreign/second/heritage language, specifically to children. TOC tools were primarily developed for the business sector as a tool for diagnosing areas which should be modified or improved. Applied in the sphere of education, the tools turned out to be universal methods of supporting students’ cognitive processes. In the existing research on the possible applications of the TOC methodology, no attention was paid to its use in the field of Polish as a non-native language didactics, and the TOC tools seem to be a useful solution in teaching foreign languages to children. The article presents proposals for the use of the so-called logical branch to explain grammar rules in teaching Polish to children. The discussed tool may perform this function well as it conforms to the standards of the methodology appropriate in children’s language education: It is attractive as a graphic tool, it shows the structure of the Polish language system in a transparent and orderly manner, it has mnemonic values, it can be also used for games, as well as allowing for flexibility (differentiation) of the didactic process.
Collocations of dimension adjectives with the names of human body parts in Polish and Korean
Authors: Szalkowska-Kim Emilia
Published: December 2019

This article presents the results of comparative research into the collocations of the names of human body parts with dimension adjectives. The aim of the analysis was to indicate the similarities, limitations and differences in the manners of conceptualising the world established in Polish and Korean, or more precisely: how both languages define the elements of the world of human body parts, and how they assign dimensions to the elements depending on the needs and experiences of native users of both. The results of the research could have a practical application in teaching both languages, facilitating students’ absorption of the lexis of the other language, and result in a deeper mutual understanding of linguistic and cultural differences..
Czy mogę odczuwać hygge, jeśli w polszczyźnie nie ma takiego wyrazu? O (nie)przekładalności emocji w kontekście glottodydaktycznym
Authors: Rabczuk Anna
Published: December 2019

Natura emocji to zagadnienie od wielu lat frapujące psychologów, psychiatrów, lingwistów, neurobiologów i wielu innych badaczy. Trudno sobie wyobrazić życie bez uczuć. Szczególnie dzisiaj człowiek poświęca wiele czasu i energii na wprawianie siebie w dobry nastrój. Zabiegi te jednak wcale nie ułatwiają kwestii mówienia o emocjach. W artykule tym autorka zastanawia się nad implikacjami lingwakulturowymi w odniesieniu do nauczania języka emocji po polsku. Poszukuje zależności między kontekstem kulturowym a doborem konkretnych środków językowych w określonych sytuacjach emocjonalnych w różnych językach. Przygląda się historyczności emocji, skryptom kulturowym, a także ładunkom kulturowym zawartym w poszczególnych leksemach. Proponuje wiele ćwiczeń, które można wykorzystać zarówno na zajęciach z cudzoziemcami, jak i lektorkami i lektorami języków obcych.
Poder punitivo e produção do espaço: uma leitura de discursos institucionais sobre conflito e controle no centro de Salvador-BA
Authors: Matos Lucas
Published: December 2019

Este trabalho tem como problema central a atuação – material e simbólica – do poder punitivo como produtor de espacialidades urbanas, tendo como ancoragem empírica o Centro da cidade de Salvador no período de 2013 a 2016. O recorte temporal se refere à gestão de ACM Neto na prefeitura da cidade, marcada pela adoção retórica do empreendedorismo urbano, tendo a segurança e ordem pública como temas políticos centrais. O percurso metodológico partiu de observação exploratória em torno da atuação das instituições de controle (Secretaria de Ordem Pública, Guarda Civil Municipal e Policia Militar) em situações cotidianas e especiais (como as festas populares) do Centro da cidade, com a produção de notas descritivas e analíticas em caderno de campo. O eixo empírico central da pesquisa, contudo, são entrevistas com personagens importantes dessas instituições que exercem atividades de controle na região. A realização das entrevistas buscou escapar de maniqueísmos, com a intenção de ler criticamente os discursos institucionais como um importante caminho de interpretação e levantamento de novas questões. A partir desses caminhos de pesquisa, o trabalho discute as interações entre controle e conflito social transgredindo os tradicionais binômios normativos lícito/ilícito penal e crime/punição e concentrando o olhar nas dinâmicas de produção da cidade potencializadas pela gestão diferenciada dos espaços, em um movimento de criminalização racializada que articula pessoas em situação de rua, trabalhadores de rua, prostitutas e autores de pequenos furtos sob o signo comum de sujeitos da desordem e da criminalidade.
Vulnerabilidade e envelhecimento: um estudo das Instituições de Longa Permanência em Sergipe
Authors: Sposato Karyna Batista , Morais Douglas Farias de , Lage Renata Carvalho Martins
Published: December 2019

O artigo sintetiza questões abordadas na pesquisa com o tema: Um Olhar sobre Direitos Fundamentais nas Instituições de Longa Permanência para Idosos (ILPI) de Sergipe. A discussão sobre as dificuldades dos gestores em meio aos desafios de promover as garantias de direitos pretendidas pela Política Nacional do Idoso, pelo Estatuto do Idoso, e pela Constituição de 1988 traz importantes contribuições para a análise do Direito Asilar no Brasil. Ao tratar das limitações legislativas, o artigo destaca dispositivos que na tentativa de proteger, acabam por limitar a autonomia do idoso e considera as questões da senescência, da senilidade e das características sociais das ILPIs, como fatores contribuintes da perda de autonomia, que tendem a provocar um afastamento do idoso de outros convívios sociais. Além disso, o estudo apresenta os resultados da pesquisa com gestores das ILPIs em 2018, comparando com os dados da pesquisa realizada pelo Instituto de Pesquisas Econômicas Aplicadas (IPEA) em 2008, revelando-se o aumento do número total de idosos residentes em ILPI e uma queda percentual de residentes em relação à população total de idosos em Sergipe. Os resultados indicam grandes dificuldades financeiras das instituições para a manutenção dos serviços e uma transferência da responsabilidade do poder executivo para instituições filantrópicas em relação à criação e manutenção das ILPIs em Sergipe, demonstrando-se que a fragilidade das políticas públicas agrava a vulnerabilidade dos idosos.
Desempenho em Juizados Especiais no Brasil: uma análise do período 2009-2016
Authors: Silva Jeovan Assis , Ferreira Guilherme Viana , Prata Ana Aires
Published: December 2019

Este artigo tem como objetivo principal comparar o desempenho dos juizados especiais na Justiça Estadual Brasileira, entre os anos 2009 e 2016, sob a ótica da produção e produtividade. Os juizados especiais são um marco institucional em resposta às pressões oriundas dos problemas de morosidade e da falta de acesso à justiça no Brasil. Críticas recentes, contudo, alertam que esse modelo de justiça já parece sofrer da mesma morosidade que almejou combater. A presente pesquisa busca preencher uma lacuna de estudos escassos voltados para a avaliação do desempenho judicial brasileiro. Dados secundários oficiais foram analisados por meio de técnica econométrica de regressão em painel, utilizando como variável dependente o Índice de Produtividade dos Magistrados nos Juizados Especiais e, como variáveis independentes, total de servidores da área judiciária, total de magistrados, casos novos e carga de trabalho. Os resultados indicam que o crescimento dos casos novos, ao longo dos anos, tem ocasionado o aumento, em menor proporção, da produtividade, enquanto que o aumento do quantitativo de magistrados está relacionado a uma piora no desempenho dos juizados especiais. A pesquisa complementa estudos prévios de objetivo similar e aponta para fragilidades do modelo dos juizados que precisam ser enfrentadas.