bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring Curriculum Congruence and Connectivity within School-Based Agricultural Education
Authors: Moser Eric M. , McKim Aaron J.
Published: June 2021

Teacher connectivity represents a relatively new and exciting construct within school based agricultural education. Existing research identifying a relationship between teacher connectivity and career commitment illuminates the need for additional research on teacher connectivity within schoolbased agricultural education. Framed using the Relational Theory of Working, the current research analyzes four facets of teacher connectivity (i.e., connection to the community, curriculum, school, and other school-based agricultural education teachers) alongside curriculum congruence, years of teaching experience, and teacher certification type. Results illustrate, among the majority of respondents, personal interest toward an agricultural subject exceeds the presence of that topic within their program. Across all areas studied, only 17.65% of responding teachers experienced alignment between their personal interests and level of curriculum represented within their program. Furthermore, results from this investigation highlight connectivity is highest among teachers who experience congruence between the presence of their curriculum and their personal interests, teachers later in their career, and teachers traditionally certified. In concert, results highlight teacher characteristics which may predispose a teacher to struggle establishing connections within the profession. Recommendations for research and practice are framed by aligning the theoretical framework, findings, and conclusions.
Carole King's Tapestry
Authors: Glass Loren
Published: June 2021

Carole King’s Tapestry is both an anthemic embodiment of second-wave feminism and an apotheosis of the Laurel Canyon singer-songwriter sound and scene. And these two elements of the album’s historic significance are closely related insofar as the professional autonomy of the singer-songwriter is an expression of the freedom and independence women of King’s generation sought as the turbulent sixties came to a close.

Aligning King’s own development from girl to woman with the larger shift in the music industry from teen-oriented singles by girl groups to albums by adult-oriented singer-songwriters, this volume situates Tapestry both within King’s original vision as the third in a trilogy (preceded by Now That Everything’s Been Said and Writer) and as a watershed in musical and cultural history, challenging the male dominance of the music and entertainment industries and laying the groundwork for female dominated genres such as women’s music and Riot Grrrl punk.
Determination of Immune Signal–Receptors, PD-1 and PD-L1, Interactions in Solution using qFRET Technology
Authors: Nwangwu Mary , Liao Jiayu
Published: June 2021

Human PD-L1 (programmed cell death 1 - ligand 1) is a transmembrane protein that is highlyexpressed on the membrane of cancer cells. It binds to inhibitory receptor PD-1 (programmed celldeath protein - 1), which is expressed on the surface of cytotoxic T cells. The interaction betweenPD-L1 and PD-1 reduces the effect of anti-tumor immune response and the strategy of blocking theirinteraction has been used for anti-cancer drug manufacture. Past studies isolated the extracellulardomain of PD-L1 for characterization of the structure. This study aims to recover, isolate, and purifythe insoluble PD-L1 protein (external domain), and study its binding interaction with PD-1 forthe development of an in vitro quantitative FRET (qFRET) assay. To report PD-L1/PD-1 bindinginteraction, fluorescent donor and acceptor pairs, CyPet and YPet were bound to PD-L1 and PD-1proteins respectively and qFRET was applied to assess the interaction of the two proteins basedentirely on fluorescence.The results provide evidence of recovery of the purified and refolded CyPet-Ext.PDL1 and YPet-Ext.PD1 proteins from cell pellets, shown in the coomassie stained SDS-PAGE gel. This study alsoshows that the proteins were able to be recovered through affinity chromatography under denaturingconditions. The qFRET technique showed that the acceptor, YPet-Ext.PD1, is interacting with thedonor, CyPet-Ext.PDL1. This study provides a novel method for better understanding the bindingmechanism of PD-L1/PD-1 that can be applied to other cell-surface protein interactions, as well as tostipulate a platform for small molecule inhibitor related drug screenings and production.
Evaluating Greenhouse Gas Emissions From Soil Application of Anaerobic Organic Digestive Compared With Conventional Manure
Authors: Abonce Guadalupe , Zhao Sharon , Rodrigues Michael , Hopkins Francesca
Published: June 2021

The state of California is investing in anaerobic digesters to reduce methane emissions from agriculture. However, little is known about the impact of anaerobic digesters on nitrous oxide (N2O) and carbon dioxide (CO2) emissions from soils after land application of digestate. The purpose of this study was to compare soil CO2 and N2O emission fluxes from anaerobic digestate treatment in conjunction with manure, manure treatment, and a control group without treatment on agricultural soils from two dairy farms. In addition to comparing treatments and sites, we tested the effects of temperature at either 23°C or 28°C to compare predicted future average temperatures. Soil samples were placed in mason jars with 18 jars per location: three manure treatments x 2, temperatures x 3 replications per treatment, and incubated for six weeks according to the temperature treatment. Soils were watered once a week to maintain 65% water holding capacity. Cavity ring-down spectrometers were used to collect gas emissions in a closed-loop system, and elemental analyzers were used to evaluate soil and treatment nutrient composition. We hypothesized that three main variables — manure, lower temperatures, and soils with low-nutrient content in conjunction with anaerobic diges- tate would all lead to lower emissions. Anaerobic digestate has been found to reduce greenhouse gas emissions while also being a nutrient-rich energy source. Microbial soil communities are also more active in warmer temperatures, which may increase the production of gas emissions. Overall, the results were inconclusive for either argument.
The Effect Of Shame And Guilt On Students Writing Habits
Authors: Gutierrez Daniel , Horton Calen , Murray Carolyn
Published: June 2021

Individuals strive to assuage negative emotions through a myriad of mechanisms, some of which are adaptive while others are not. In the current study, we focus on shame and guilt. Previous research suggests that shame is more associated with defensiveness and the tendency to project negative feelings outward. However, guilt can be an adaptive emotion and is associated with the tendency to take responsibility. The current study explores how such negative emotionality can affect students’ perceived and actual work habits by utilizing Google Docs, which keeps a time-stamped record of workers’ activity that is accurate to the millisecond. Participants (n = 178) were asked to write an essay into Google Docs. Participants also completed self-reported procrastination scales and the Test of Self-Conscious Affect (TOSCA). Therefore, we can compare participants’ self-reported levels of shame and guilt with both their self-reported procrastination and their actual work activity (measured by utilizing the time-stamped data). While both shame-proneness and guilt-proneness are significant predictors of self-reported procrastination, neither predict observed procrastination. Despite this, self-reported procrastination is associated with observed procrastination. Ultimately, this data can be used to better understand students’ perceived and actual work habits and motivations from a psychological perspective and can assist in informing others regarding how to best engage with students concerning their writing activity and habits.
Development Of Quantitative Förster Resonance Energy Transfer (QFRET) Based High Throughput (HTS) Screening For PD-1/PD-L1 Immune-Checkpoint Assay
Authors: Xaypraseuth Amanda , Madahar Vipul , Liao Jiayu
Published: June 2021

Programmed cell death protein 1 (PD-1) and programmed cell death 1 - ligand 1 (PD-L1) are immune-checkpoint proteins that play an important part in cancer immunity. PD-1 is a protein on the surface of cells that down-regulates the immune system1 while PD-L1 is a protein on some normal and cancer cells. The interaction of these proteins play a major role in tumor immune escape, inhibiting T lymphocyte proliferation and survival functions. To combat this issue, targeting these immune checkpoint proteins with monoclonal antibodies (mAbs) has become the turning point in cancer treatment. However, limitations were found using mAbs such as the cost of administration, its high molecular weight, and its lack of clinical efficacy. Recently, researchers are investigating small molecule inhibitors to target the PD-1/PD-L1 mechanism instead. With CA-170 as the only small-molecule modulator in clinical trials targeting PD-1, it is essential to research options that can contribute to cancer treatments. This study provides a novel, rapid assessment for PD-1/PD-L1 interaction with the use of FRET- based kinetic analysis. PD-1/PD-L1 binding will be quantified by fluorescence using donor and acceptor pairs, CyPet and Ypet, which were bound to PD-L1 and PD-1, respectively. From this study, we calculated a Kd value of 0.31±0.13 and developed an HTS assay with a Z’ value > 0.7, values that validate the robustness and efficacy of this assay. With the development of this type of screening, it will be easy to contribute to small molecule inhibitor discovery and the growing field of cancer immunotherapy.
Allicin depresses biological activities of pancreatic cancer cells by regulating miRNA-339-5p/ZNF-689 axis
Authors: Yu Zeqian , Zhao Susu
Published: June 2021

Introduction

The aim of this study was to discuss Allicin’s anti-tumor effects and relative in pancreatic cancer cell via vitro and vivo study.

Material and methods

Using PANC-1 and Hs766T cell as research cell lines in our study. The PANC-1 abd GS799T cell were respectively treated with difference concentrations of Allicin. In next step, the PANC-1 abd GS799T cell were transfected with si-miRNA-339-5p which knockdown miRNA-339-5p. The cells were treated with difference concentration of Allicin. Measuring cell proliferation, apoptosis, invasion and migration by MTT, EDU, flow cytometry, TUNEL, transwell and wound healing assay. Relative gene (miRNA-339-5p, ZNF-689, Caspase-3, Caspase-8, E-cadherin and Vimentin) and protein (ZNF-689, Caspase-3, Caspase-8, E-cadherin and Vimentin) expression were evaluated by RT-qPCR and WB assay.

Results

Allicin had effects to suppress PANC-1 and Hs766T cell biological activities including cell proliferation, invasion and migration with cell apoptosis significantly increasing, however, with si-miRNA-339-5p which inhibit miRNA-339-5p expression transfection, the cells biological activities enhancing with cell apoptosis depressing, Compared with NC group, miRNA-339-5p, Caspase-3, Caspase-8 and E-cadherin expression were significantly increased and ZNF-689 and Vimentin expression were significantly depressed in Allicin treated groups, however, with miRNA-339-5p inhibitor transfection, the Allicin’s effects significantly disappear.

Conclusions

Allicin had anti-tumor effect to pancreatic cancer biological activities via regulation miRNA-339-5p/ZNF-689 axis in vitro study.
Assessment of cardiac function and subclinical atherosclerosis in children with systemic lupus erythematosus
Authors: Wagdy Reham , El Shafie Mohammed , El-Kersh Mohie
Published: June 2021

Introduction

Juvenile onset systemic lupus erythematosus (JSLE) is an autoimmune disease associated with high cardiovascular morbidity. The purpose of the study was to assess cardiac function and subclinical atherosclerosis among children with SLE and to establish risk factors.

Material and methods

Data on thirty children with SLE followed up at Alexandria Main Children Hospital were collected and compared to thirty matched controls. The collected data were about demographics, systemic examination and laboratory findings. However, all participants were subjected to echocardiography, pulsed wave tissue Doppler (PWTD) and sonographic assessment of intima media thickness of the abdominal aorta (aIMT) and carotid arteries (cIMT).

Results

The patient group with mean age of 11.3 ±2 years and mean duration of disease 3.2 ±2.3 years included 63.3% (n = 19) hypertensive cases with no heart failure. High cholesterol values were reported in 30%. The main findings of the imaging studies of patients showed significantly low ejection fraction (EF) (57.9 ±5.8, p < 0.001) and low mitral annular velocities at septal and lateral walls at peak systole (Sm) and peak early diastolic filling (Em) (p < 0.001). Also there were significantly high aIMT (1.1 ±0.3) and cIMT (0.5 ±0.7) for patients. The duration of the disease and aIMT were significant risk factors that negatively affect Sm and Em of lateral wall (p ≤ 0.05).

Conclusions

In JSLE, impaired LV function and subclinical atherosclerosis were prevalent specially among children with longer disease duration which highlight the need for periodic checkup by ultrasonography and PWTD.
A Holistic Self-Adaptive Software Model
Authors: Alfar Shatha , Ghoul Said
Published: June 2021

The recent self-adaptive software systematic literature reviews stated clearly the following insufficiencies: (1) the need for a holistic self-adaptive software model to integrate its different aspects (2) The limitation of adaptations to context changes (3) The absence of a general and complete adaptations’ picture allowing its understandability, maintainability, evaluation, reuse, and variability. (4) The need for an explicit and a detailed link with resources, and (5) a usual limitation to known events. In order to metigate these insufficiencies, this paper is proposing a holistic model that integrates the operating, adaptations, and adaptations’ manager aspects. The proposed model covers all possible adaptations: operating (dealing with software functions failures), lifecycle (handling adaptations required by some software lifecycle steps), and context (facing context changes events). The presented work introduces the concept of software adaptations process integrating the specifications of all the above kind of adaptations. In fact, this work shows an explicit trace to its pure bio-inspired origin.An application of the proposed approach on a “car industry case study” demonstrated its feasibility in comparison with similar works that proved its meaningful added value and its promising research perspectives.
The Effectiveness of Human Resource Development Management in Efforts to Improve The Quality of Education in SD Negeri 90 Ogan Komering Ulu
Authors: Dauzar Dauzar , Fitria Happy , Putra Alhadi Yan
Published: June 2021

This study aims to determine the effectiveness of human resource development management to increase quality at SD Negeri 90 Ogan Komering Hulu (OKU). This research is a qualitative research with  qualitative descriptive approach. The data obtained were collected through observation, interview and documentation techniques. The results showed that the human resource development steps carried out at SD Negeri 90 OKU were carried out in 7 steps, namely compiling programs, determining needs, determining targets, determining programs, identifying learning principles, program implementation and evaluation of program implementation. Human resource management at SD Negeri 90 OKU, both in terms of quality improvement, implementation, supporting factors and the quality of education have been running optimally.
Experiencia clínica con ipilimumab en el tratamiento de melanoma metastásico o irresecable en el Instituto Nacional de Cancerología, Bogotá, Colombia : serie de casos.
Authors: Pinilla Paola Andrea , Brugés Maya Ricardo Elías , Sánchez Pedraza Ricardo
Published: June 2021

Objetivo: el presente estudio pretende describir las características clínicas, progresión y mortalidad de pacientes con melanoma metastásico o irresecable tratados con ipilimumab en el Instituto Nacional de Cancerología entre enero de 2013 y junio de 2015. Métodos: se realizó un estudio descriptivo, retrospectivo, en pacientes mayores de 18 años con diagnóstico de melanoma metastásico o irresecable en tratamiento con ipilimumab durante enero de 2013 a junio de 2015 en el Instituto Nacional de Cancerología en Bogotá (Colombia). Se efectuó análisis descriptivo de las variables cuantitativas por medidas de tendencia central y de dispersión, y de las variables cualitativas por medio de frecuencias y porcentajes. Se llevó a cabo análisis de comparación de supervivencia con los datos (Kaplan-Meier). Resultados: se identificaron un total de 22 pacientes, con una edad promedio de 60,7 años (DE 15,2). Un 27,3% recibió el manejo como primera línea; el 59%, como segunda línea; y el 13,6%, como tercera línea. El 59% terminó los cuatro ciclos de tratamiento y el 40,9% tuvo un esquema incompleto, dado por toxicidad limitante en el 18,2%, progresión de la enfermedad en el 9,1% y muerte en el 9,1%. Se encontró una tasa de mortalidad del 0,0106/100 mil pacientes al mes [IC95% 6,15-18,2] y una mediana de supervivencia postratamiento de 6 meses [IC95% 3,78-8,21]. Conclusiones: este estudio descriptivo retrospectivo sugiere que el uso de ipilimumab en nuestra población tiene una eficacia y seguridad inferior a la reportada en estudios internacionales de aprobación de la molécula, por lo cual se hace necesario ampliar los datos nacionales, con la colaboración interinstitucional, para conocer el comportamiento a nivel país de la enfermedad, y con ello también se debe proponer un análisis de costo-efectividad ajustado a nuestra población.
O PNE E A EDUCAÇÃO SUPERIOR NO BRASIL
Authors: Guimarães André Rodrigues , Santiago Francisco Orinaldo Pinto , Barleta Ilma De Andrade , Mororó Leila Pio
Published: June 2021

O objetivo deste artigo é analisar o processo de expansão e interiorização da educação superior no Brasil, no contexto de vigência inicial do Plano Nacional de Educação, Lei n. 13.005/2014. Trata-se de pesquisa fundamentada no materialismo histórico-dialético cujo os dados analisados foram extraídos do Censo da Educação Superior do Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira, órgão vinculado ao Ministério da Educação. Para tanto, considera-se especificamente as categorias de conteúdo expansão, interiorização, público e privado, com base nos dados da evolução no número de Instituições, Cursos e matrículas na educação superior no período de 2014 a 2018. A análise mostrou que a política de expansão da educação superior induzida pela meta 12 do PNE vigente apresenta traços de continuidade e aprofundamento da lógica de mercado na educação.
Introducing Ice Nucleating Particles functionality into the Unified Model and its impact on the Southern Ocean short-wave radiation biases
Authors: Varma Vidya , Morgenstern Olaf , Furtado Kalli , Field Paul , Williams Jonny
Published: June 2021

Abstract. Insufficient reflection of short-wave radiation especially over the Southern Ocean region is still a leading issue in many present-day global climate models. One of the potential reasons for this observed bias is an inadequate representation of clouds. In a previous study, we modified the cloud micro-physics scheme in the Unified Model and showed that choosing a more realistic value for the capacitance or shape parameter of atmospheric ice-crystals, in better agreement with theory and observations, benefits the simulation of short-wave radiation over the Southern Ocean by brightening the clouds. However, attempts to modify the cloud phase by directly adjusting the micro-physics process rates like capacitance tend to affect both the hemispheres symmetrically whereas we seek to brighten only the high-latitude Southern Hemisphere clouds. In this study we implement a simple prognostic parametrisation whereby the heterogeneous ice nucleation temperature is made to vary three-dimensionally as a function of the mineral dust distribution in the model. As a result, those regions with less dust number density would have lower nucleation temperature compared to the default global value of −10 °C. By using mineral dust as an indicator for ice nucleating particles in the model, this parametrisation thus captures the impact of ice nucleating particles on the cloud distribution due to its general paucity over the Southern Ocean region. This approach thus improves the physics of the model with minimal complexity.
Benchmarking microbarom radiation and propagation model against infrasound recordings: a vespagram-based approach
Authors: Vorobeva Ekaterina , De Carlo Marine , Le Pichon Alexis , Espy Patrick Joseph , Näsholm Sven Peter
Published: June 2021

Abstract. This study investigates the use of a vespagram-based approach as a tool for multi-directional comparison between simulated microbarom soundscapes
and infrasound data recorded at ground-based array stations. Data recorded at the IS37 station in northern Norway during 2014–2019 have been
processed to generate vespagrams (velocity spectral analysis) for five frequency bands between 0.1 and 0.6 Hz. The back azimuth resolution
between the vespagram and the microbarom model is harmonized by smoothing the modeled soundscapes along the back azimuth axis with a kernel
corresponding to the frequency-dependent array resolution. An estimate of similarity between the output of the microbarom radiation and propagation
model and infrasound observations is then generated based on the image-processing approach of the mean square difference. The analysis reveals that
vespagrams can monitor seasonal variations in the microbarom azimuthal distribution, amplitude, and frequency, as well as changes during sudden
stratospheric warming events. The vespagram-based approach is computationally inexpensive, can uncover microbarom source variability, and has the potential for near-real-time stratospheric diagnostics and atmospheric model assessment.
Does maximization of net carbon profit enable the prediction of vegetation behaviour in savanna sites along a precipitation gradient?
Authors: Nijzink Remko Christiaan , Beringer Jason , Hutley Lindsay Beaumont , Schymanski Stanislaus Josef
Published: June 2021

Abstract. Most terrestrial biosphere models (TBMs) rely on more or less detailed information about the properties of the local vegetation. In contrast, optimality-based models require much less information about the local vegetation as they are designed to predict vegetation properties based on general principles related to natural selection and physiological limits. Although such models are not expected to reproduce current vegetation behaviour as closely as models that use local information, they promise to predict the behaviour of natural vegetation under future conditions, including the effects of physiological plasticity and shifts of species composition, which are difficult to capture by extrapolation of past observations. A previous model intercomparison using conventional terrestrial biosphere models (TBMs) revealed a range of deficiencies in reproducing water and carbon fluxes for savanna sites along a strong precipitation gradient of the North Australian Tropical Transect (Whitley et al., 2016). Here we examine the ability of an optimality-based model (the Vegetation Optimality Model, VOM) predict vegetation behaviour for the same savanna sites. The VOM optimizes key vegetation properties such as foliage cover, rooting depth and water use parameters in order to maximize the Net Carbon Profit (NCP), defined here as the difference between total carbon taken up by photosynthesis minus the carbon invested in construction and maintenance of plant organs. Despite a reduced need for input data, the VOM performed similarly or better than the conventional TBMs in terms of reproducing the seasonal amplitude and mean annual fluxes recorded by flux towers at the different sites. It had a relative error of 0.08 for the seasonal amplitude in ET, and was among the best three models tested with the smallest relative error in the seasonal amplitude of gross primary productivity (GPP). Nevertheless, the VOM displayed some persistent deviations from observations, especially for GPP, namely an underestimation of dry season evapo-transpiration at the wettest site, suggesting that the hydrological assumptions (free drainage) have a strong influence on the results. Furthermore, our study exposes a persistent overprediction of vegetation cover and carbon uptake during the wet seasons by the VOM. Our analysis revealed several areas for improvement in the VOM, including a better representation of the hydrological settings, as well as the costs and benefits related to plant water transport and light capture by the canopy. The results of this study imply that vegetation optimality is a promising approach to explain vegetation dynamics and the resulting fluxes. It provides a way to derive vegetation properties independently from observations, and allows for a more insightful evaluation of model shortcomings as no calibration or site-specific information is required.
Development and parameter estimation of snowmelt models using spatial snow-cover observations from MODIS
Authors: Gyawali Dhiraj Raj , Bárdossy András
Published: June 2021

Abstract. Given the importance of snow on different land and atmospheric processes, accurate representation of seasonal snow evolution including distribution and melt volume, is highly imperative to any water resources development trajectories. The limitation of reliable snow-melt estimation in these regions is however, further exacerbated with data scarcity. This study attempts to develop relatively simpler extended degree-day snow-models driven by freely available snow cover images in snow-dominated regions. This approach offers relative simplicity and plausible alternative to data intensive models as well as in-situ measurements and have a wide scale applicability, allowing immediate verification with point measurements. The methodology employs readily available MODIS composite images to calibrate the snow-melt models on snow-distribution in contrast to the traditional snow-water equivalent based calibration. The spatial distribution of snow cover is simulated using different extended degree-day models calibrated against MODIS snow-cover images for cloud-free days or a set of images representing a period within the snow season. The study was carried out in Baden-Württemberg in Germany, and in Switzerland. The simulated snow cover show very good agreement with MODIS snow cover distribution and the calibrated parameters exhibit relative stability across the time domain. The snow-melt from these calibrated models were further used as standalone inputs to a “truncated” HBV without the snow component in Reuss (Switzerland), and Horb and Neckar (Baden-Wuerttemberg) catchments, to assess the performance of the melt outputs in comparison to a calibrated standard HBV model. The results show slight increase in overall NSE performance and a better NSE performance during the winter. Furthermore, 3–15 % decrease in mean squared error was observed for the catchments in comparison to the results from standard HBV. The increased NSE performance, albeit less, can be attributed to the added reliability of snow-distribution coming from the MODIS calibrated outputs. This paper highlights that the calibration using readily available images used in this method allows a flexible regional calibration of snow cover distribution in mountainous areas across a wide geographical extent with reasonably accurate precipitation and temperature data. Likewise, the study concludes that simpler specific alterations to processes contributing to snow-melt can contribute to identifying the snow-distribution and to some extent the flows in snow-dominated regimes.
Lesões não cariosas: revisão de literatura
Authors: Pinheiro Camila Ferreira , Melo Miréia Pinto Ferreira , Silva Rafael Rodrigues da , Pedron Irineu Gregnanin , Shitsuka Caleb
Published: June 2021

As lesões não cariosas são um conjunto de lesões que podem ocorrer e apresentam característica de perda da estrutura dental sem estar ligada ao fator cárie, elas ocorrem por uma associação de alguns fatores, o que caracteriza uma etiologia multifatorial. Dentre essas lesões temos a abfração, abrasão, atrição e erosão. O objetivo deste trabalho foi realizar uma revisão de literatura comentando sobre as principais características das lesões não cariosas. Na metodologia foram considerados 12 arquivos no período de 2002 a 2020, com base em dados inglês e português: Scielo, PubMED, Google Acadêmico. Concluímos que é de extrema importância que o cirurgião-dentista deva realizar uma boa anamnese e exame clínico criterioso, para que possa dar um diagnóstico precoce e. Para um tratamento adequado deve ser realizado um planejamento de acordo com a lesão e seu estágio de severidade. É importante remover os fatores causais das lesões, assim evitando a progressão e surgimento de novas lesões.
Flourishing: Role of Perseverance and Passion for Long-Term Goals in Relation to Subjective Vitality
Authors: Padhy Meera , Hariharan Meena , Mutnury Suma Lavanya
Published: June 2021

Several psychosocial factors contribute to flourishing which is a state of optimal human functioning. The objectives of this study were to explore the relationship between grit, vitality and flourishing; and to assess the impact of grit and vitality on flourishing. A correlational design was used to collect data from 449 participants (211 women and 238 men) aged between 18-57 years. The Flourishing Scale, the Grit Scale and the Subjective Vitality Scale were administered. The obtained data were scored and analyzed suitably. Results revealed positive relationships between all the variables. Further, hierarchical multiple regression analyses showed that grit and vitality significantly predicted flourishing. Results from this study indicate the need to further investigate the impact of grit and vitality on an important positive psychological construct like flourishing.

Key words: flourishing, grit, vitality, regression, correlation, well-being.
Effect of Tai Chi and Stepping Exercise for Balance Training in Geriatrics: Randomized Control Trial
Authors: Mhaske Gaurav C. , Fursule Darshana , Khairnar Anagha
Published: June 2021

Introduction: Approximately 40% of geriatric population in India experience some form of balance difficulty. It may be due to decreased muscular strength, flexibility, impaired vision and hearing problem. There are many approaches for improving balance such as Tai Chi exercise, stepping exercise, wobble board exercises, strengthening exercises. Tai Chi is a series of slow, smooth and graceful movements for improving neuromuscular function, endurance, joint sense and cognitive function. Stepping exercise is exercise performed using stepper. It improves balance by strengthening muscles, flexibility and range of motion.
Objective: To compare the effect of Tai Chi and stepping exercise for improving balance in geriatric population.
Method: In the present study, 40 participants of age group 60-80 years with balance problem were taken. Random sampling was done in two group, group A (n=20) and group B (n=20) giving Tai Chi and Stepping exercise respectively. Outcome measured used were BBS, TUG, FES and POMA.
Results: In present study, Tai Chi exercise was more effective than Stepping exercise statistically proved with unpaired t test BBS (p=0.0001), TUG(p=0.0001), FES (p=0.0679) and POMA (p=0.0039). When comparison was done within the groups, all outcome measures showed significant values at pre and post intervention, BBS (p=<0.0001 in group A and B), TUG (p=<0.0001 in group A and B), FES (p=<0.0001 in group A and B) and POMA (p=<0.0001 in group A and B),
Conclusion: Tai Chi exercise showed more effect than Stepping exercise in geriatric population with balance impairments.

Key words: Tai Chi exercise, stepping exercise, geriatric population, Balance Training in Geriatrics, balance impairments.
FPD Supported Cu-Sil Like Denture - A Simplified Approach to Preserve the Teeth and Bone
Authors: Savitha K. , PS Manoharan , E Rajkumar
Published: June 2021

Cu-Sil denture is a simplified approach which helps in preserving the few remaining natural teeth .It is a new type of transitional denture which clasps the neck of the tooth providing space for the remaining teeth to emerge into the oral cavity through the denture. Preserving the remaining teeth not only preserves the alveolar ridge but also maintains proprioception providing psychological benefit for the patient. Cu-Sil denture is one such simpler clinical approach which offers many advantages. This case report represents a simple chair-side clinical approach to fabricate Cu-Sil denture by preserving the few natural teeth.

Key words: Cu-Sil denture, transitional denture, proprioception.
A Rare Case of Isolated Cecal Necrosis
Authors: Sravani Challa , Killedar Madhura M
Published: June 2021

Isolated cecal necrosis is a rare abdominal condition. Usually presents as acute appendicitis clinically. Mostly occurring in older patients with cardiac and renal comorbidities. Anatomical abnormality of cecal blood supply is usually observed. Diagnosis is difficult preoperatively without high degree of suspicion. Any delay in diagnosis can lead to fatal complication.

Key words: isolated cecal necrosis, ischemic colitis, acute appendicitis.
An Atypical Adult Presentation of Acute Clonidine Intoxication: A Case Report
Authors: Theresa Manna Maria , K Arunkumar , K P Gireesh Kumar
Published: June 2021

Clonidine is drug which was initially used as a nasal decongestant and now commonly used in the treatment of several conditions both in adults and children. Even though there is no minimum toxic dose for this drug, low-dose clonidine poisonings are commonly seen in children. Accidental ingestion of this drug or transdermal exposure can cause altered sensorium, hypertension, hypotension and bradycardia because of various mechanism of action.

Key words: Clonidine, intoxication, hypotension, miosis.
The Impact of Interregional Economic Differentiation on the Economic Security of the Regions of Ukraine
Authors: Lebedchenko Vira V.
Published: June 2021

Interregional economic differentiation is common in most countries. On the one hand, economic differentiation is a natural phenomenon, on the other hand, it demonstrates the inefficiency of the national budget policy. However, to develop effective mechanisms for reducing interregional economic differentiation, its objective assessment is a priority. The purpose of this study is to analyse and evaluate the socio-economic differentiation of regional development. It considers the systematisation of theoretical provisions and methodological recommendations for the analysis and regulation of differentiation of socio-economic development of regions in the system of their economic security. The method of analysis for research of structure and dynamics of differentiation of social and economic development of regions is offered. The study proves the necessity of using a set of statistical characteristics and the method of cluster analysis. The authors of the study propose a methodical approach to the calculation of a one-dimensional relative indicator of the rank spread, which shapes an idea of the distribution of economic differentiation in the middle of the economic group under study. The methods used in problems of research of structure and dynamics of differentiation of social and economic development of regions are analysed, the technique of an estimation of level of differentiation is offered. The concept of socio-economic differentiation of regions is covered. The lines of regulation of social and economic differentiation and intensification of economic security of the region are offered. In accordance with the cluster analysis and the used adaptive method of assessing the economic security of the regions for monitoring and strategic planning of socio-economic development of the region, the socio-economic development of the regions of Ukraine was studied. According to the results of the analysis, it was found that there is a considerable discrepancy in many economic and social indicators, which may confirm the disparities in regional development
Integral Assessment of the Competitiveness of Socio-Economic Activity of the Western Regional Market of Tourism Services of Ukraine
Authors: Zaichuk Kateryna A.
Published: June 2021

The relevance of the study is that tourism is a leading field of activity in many countries, as its development provides an opportunity to use the most valuable natural resources, create new jobs, intensify investment activities, improve the environmental and socio-economic situation. Despite the actualization of the outlined problem, it is worth noting the lack of research on the market of tourist services in the Western regional market in the scientific literature, and in particular the processes of socio-economic activity and mechanisms for their regulation. The following research methods were used in this work: statistical, mathematical, method of analysis and cartographic. Also, statistical data of the State Statistics Service of Ukraine, the Ministry of Finance of Ukraine, the Ministry of Economic Development of Ukraine, the Ministry of Infrastructure of Ukraine, the Ministry of Social Policy, the Ministry of Development of Communities and Territories of Ukraine, etc. were used. This paper substantiates the level of competitiveness of socio-economic activity of the Western regional market of tourist services, analyses a number of scientific works of foreign and Ukrainian scientists. The main results of the study is an integrated assessment of the competitiveness of the Western regional market of tourist services. For this purpose, all-Ukrainian indicators for assessing the socio-economic development of the regions were used. The analysis revealed that the studied objects (Volyn, Rivne, Ternopil and Lviv regions) during 2015-2018 improved their level of integrated competitiveness in the market of tourism services, but it remains critically low, although it is gradually growing
Models of Team Role Composition for Completing an IT Company on a Fuzzy Set Platform
Authors: Kramskyі Serhiy O. , Yevdokimova Olha M. , Zakharchenko Oleg V.
Published: June 2021

At present, in the global economic crisis and the COVID-19 pandemic, the development and operation of distance learning and student education are more relevant than ever. The COVID-19 crisis, in addition to the world pandemic, has dealt a devastating blow to the economy of the state and organisations. Insufficient level of research support, imperfection of organisational structure and organisation of management of scientific and technical activities in IT projects necessitate revision and improvement of the existing management system of such projects. The purpose of the study is to develop comprehensive models to increase the objectivity of the role assessment of the applicants' competences during the staffing of specialists for the IT company in conditions of uncertainty on the platform of fuzzy sets. The following theoretical methods of scientific cognition were used in the study: method of synthesis and analysis of information, statistical method, method of maximisation and method of Max-disjunction. The study considers the developed model for assessing the applicants' competences in the staffing of the role of specialists of the IT company using the platform of fuzzy sets. The study analyses the current problems of recruitment, human or labour resources in corporations whose activities are related to the development of software in various fields. The approximate composition of roles in modern IT companies with the recommended socionic types of information metabolism for each specific executor of the IT project is given. The incentive mechanism in the context of specific constraints enables the improvement of the system of rewarding IT staff and makes it possible to differentiate such staff using project management tools. The authors of the study have developed a fuzzy model for assessing the competences of a candidate for any position in an IT corporation. The study provides linguistic variables, the basis of the rules of fuzzy products, and the conclusion of the dependences of the output variable on the input data of the developed fuzzy model
Labour Protection as a Component of Effective Management of a Modern Enterprise
Authors: Kachynska Nataliia F. , Zemlyanska Olena V. , Husiev Arkadii M. , Demchuk Hlib V. , Kovtun Andrii I.
Published: June 2021

Occupational safety issues, especially in a large enterprise, constitute key components of the social and labour sphere, which largely affect the operation of the entire enterprise. In modern economic environment, where every company aims to produce competitive, high-quality products and make a profit, maintaining the health and efficiency of each employee is a top priority. Any socially oriented enterprise is interested, first and foremost, in reducing the level of accidents, injuries, industrial and occupational diseases of employees. The purpose of the study was to identify and assess the role of labour protection and industrial safety in the development of an effective management system and enterprise activities. In the process of research the method of comparison, analogy, formalization, structural analysis, dialectical method of cognition was used. As a result of the study, the authors determined that the modern organisation of occupational safety should be aimed at effective management of industrial safety of all technological processes and international standards, including OHSAS 18001, ISO 4501, ISO 9001, which is the basis of effective management in general and helps identify and prevent the occurrence of adverse factors and, as a consequence, minimises the occurrence of injuries and occupational diseases, loss of life, health and ability to work in general, allows identifying and preventing the occurrence of adverse factors
Prevalence of Tuberculosis/HIV co-infection in the state of Ceará: a literature review
Authors: Goes João Vitor Caetano , Laranjeira Bruno Jaegger
Published: June 2021

Based on literature review, the present study aimed to evaluate data on cases of co-infections between tuberculosis and HIV in the period from 2015 to 2018 in the state of Ceará. Between 2015-1018, there were a total of 16,776 new TB cases in the state of Ceará (Figure 1). When we analyzed the first two years (2015 and 2016), there was a minimal difference, at 1%, this figure increased in the following year (2017), from 24.02% to 25.75%, leveraging in 2018, representing a total of 26.28% of the total cases of the last 4 years, that is, there was no change above 2% over the years. However, the number of cases increases gradually. Recognizing the epidemiological status of different regions and locations allows the state to recognize and interpret more efficiently the ways of combating the diseases that so devastate humanity and take the sleep of so many scientists and government leaders. Furthermore, the correct assessment of these data allows us to understand the growth of the disease in the region, and thus help in the process of controlling and informing the population.
Resección endoscópica bajo visión coledocoscópica de pólipo biliar. Reporte de un caso
Authors: Soler Aníbal , Palmili Gonzalo , Cassone Eduardo , Silva Aníbal
Published: June 2021

Inflammatory pseudotumors of the biliary tract represent an infrequent biliary pathology, with few cases reported in literature. In radiological or surgical explorations, these tumors are usually diagnosed as unsuspected findings. They represent a challenge in preoperative diagnosis, due to the cost of specific technology such as Spyglass DS (Boston Scientific) and the need of trained personnel for its correct use. This means that most patients are usually treated with major resections with wrong preoperative diagnosis of cholangiocarcinoma, missing a chance of an endoscopic solution while adding unnecessary morbidity and mortality in benign pathology. We present a case that underwent endoscopic resection by ERCP under direct choledochoscopic view for Kehr’s biliary fístula in the General Surgery Department of a central hospital.
TINGKAT ANSIETAS PADA PASIEN HIPERTENSI PRIMER DI RSUD ABDUL WAHAB SJAHRANIE KALIMANTAN TIMUR
Authors: Ermmayani Made
Published: June 2021

Hipertensi merupakan penyakit kronis yang jika tidak dapat dikelola dengan tepat dapat meningkatkan risiko untuk pengembangan gangguan kesehatan mental khususnya ansietas dan depresi. Tujuan penelitian adalah mengetahui tingkat ansietas pada pasien hipertensi primer. Penelitian merupakan penelitian kuantitatif dengan jenis penelitian adalah penelitian deskriptif. Pengumpulan data menggunakan kuisioner Hamilton Anxiety Scale (HARS). Populasi penelitian ini adalah semua pasien hipertensi yang berkunjung ke Instalasi Rawat Jalan dan Poliklinik Jantung di RSUD Abdul Wahab Sjahranie dengan jumlah sampel adalah 91 responden. Hasil penelitian menunjukan bahwa tingkat ansietas responden mayoritas termasuk dalam ansietas ringan sebanyak 48 responden (52,7%). Pasien hipertensi primer lebih banyak mengalami tingkat ansietas ringan.
KOMPARASI HASIL BELAJAR MAHASISWA MENGIKUTI KULIAH DARING MATA KULIAH K3 ANTARA MAHASISWA YANG TINGGAL DI KOTA SAMARINDA DAN LUAR KOTA SAMARINDA TAHUN 2021
Authors: Sastrini Yovita Erin , Herni Pertiwi Gracia
Published: June 2021

Penelitian ini menguraikan tentang perbandingan hasil belajar mahasiswa dalam mengikuti kuliah daring antara mahasiswa yang tinggal di Wilayah Kota Samarinda dan di luar  Wilayah Kota Samarinda (Pelosok). Tujuan penelitian ini adalah 1) mengetahui hasil belajar mahasiswa yang mengikuti kuliah daring Mata Kuliah K3 di Kota Samarinda, 2) mengetahui hasil belajar mahasiswa yang mengikuti kuliah daring Mata Kuliah K3 di luar Kota Samarinda, 3) mengetahui perbedaan hasil belajar antara mahasiswa yang mengikuti kuliah daring Mata Kuliah K3 di Kota Samarinda dan mahasiswa yang mengikuti kuliah daring di luar Kota Samarinda.Penelitian ini merupakan penelitian komparasi dengan pendekatan kuantitatif. Sampel yang digunakan dalam penelitian ini adalah 15 orang mahasiswa yang berdomisili di Samarinda, dan 15 orang mahasiswa yang berdomisili di luar samarinda yang saat kuliah dilaksanakan tidak berada di Kota Samarinda. Data hasil belajar diperoleh berdasarkan evaluasi hasil belajar mahasiswa pada Mata Kuliah K3 di semester enam. Hasil penelitian menunjukkan bahwa rata-rata nilai mahasiswa yang mengikuti kuliah daring di kota Samarinda adalah 83.27, sedangkan rata-rata nilai mahasiswa yang mengikuti kuliah di luar Kota Samarinda adalah 81.87. Hasil uji hipotesis menggunakan Mann Whitney menunjukkan bahwa tidak ada perbedaan hasil belajar antara mahasiswa yang mengikuti kuliah di wilayah Kota Samarinda dengan mahasiswa yang mengikuti kuliah di luar kota samarinda. Penelitian selanjutnya diharapkan dapat mengembangkan penelitian ini melalui penelitian kualitatif untuk menggali pengalaman mahasiswa dalam mengikuti kuliah daring selama masa Pandemi Covid-19.
TINGKAT ANSIETAS PADA PASIEN HIPERTENSI PRIMER DI RSUD ABDUL WAHAB SJAHRANIE KALIMANTAN TIMUR
Authors: Ermayani Made
Published: June 2021

Hipertensi merupakan penyakit kronis yang jika tidak dapat dikelola dengan tepat dapat meningkatkan risiko untuk pengembangan gangguan kesehatan mental khususnya ansietas dan depresi. Tujuan penelitian adalah mengetahui tingkat ansietas pada pasien hipertensi primer. Penelitian merupakan penelitian kuantitatif dengan jenis penelitian adalah penelitian deskriptif. Pengumpulan data menggunakan kuisioner Hamilton Anxiety Scale (HARS). Populasi penelitian ini adalah semua pasien hipertensi yang berkunjung ke Instalasi Rawat Jalan dan Poliklinik Jantung di RSUD Abdul Wahab Sjahranie dengan jumlah sampel adalah 91 responden. Hasil penelitian menunjukan bahwa tingkat ansietas responden mayoritas termasuk dalam ansietas ringan sebanyak 48 responden (52,7%). Pasien hipertensi primer lebih banyak mengalami tingkat ansietas ringan.