bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence of 25-OH-Vitamin D and Calcium Deficiency in Adolescent Idiopathic Scoliosis
Authors: Herdea Alexandru ,   Department of Pediatric Orthopedics, �Grigore Alexandrescu� Emergency Hospital for Children, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Charkaoui Adham ,   Department of Pediatric Surgery, Municipal Emergency Hospital of Moinesti, Moinesti, Romania,   Faculty of Medicine and Pharmacy, �Dunarea de Jos� University of Galati, Galati, Romania, Ulici Alexandru ,   Department of Pediatric Orthopedics, �Grigore Alexandrescu� Emergency Hospital for Children, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Alexandru Ulici, M.D., PhD, Associate Professor, “Carol Davila” University of Medicine and Pharmacy, Pediatric Orthopedics Department, �Grigore Alexandrescu� Emergency Hospital for Children, Bucharest, Romania, 30-32 Iancu de Hunedoara Blvd., Bucharest, District 1, 011743, Phone: +40723188988, E-mail: alexandruulici@yahoo.com
Published: November 2022

Several etiologies have been proposed as a basis and evolution theory for the development of adolescent idiopathic scoliosis, but limited data were published until now that link vitamin D and calcium deficiency to this condition. The present study aims to evaluate the relationship between 25-OH-Vitamin D, total calcium, and the following data: Cobb angle, age, and patient sex. The seasonal variation for vitamin D will also be taken into consideration. A total of 101 patients with a mean age of 11.61 ± 2.33 years had vitamin D and calcium levels tested. The mean Cobb angle was 26.21o ± 12.37. The level of vitamin D was, on average, 24 ng/mL ± 9.64. Calcium values were within the normal range, with an average of 9.82 mg/dL ± 0.42. The male group showed lower levels of vitamin D compared to the female group (19.6 vs. 25.45 ng/mL) (p = 0.02). Seasonal variations showed significant differences for vitamin D (p=.0001). Vitamin D level was positively correlated with the calcium level (p=0.01, r=0.973), but also with the patient�s age (p <0.001, r=0.158). The Cobb angle was negatively correlated with serum vitamin D levels (p<0.01, r=-0.472). Patients included in this study had low vitamin D levels, significant differences being observed between boys and girls, boys being more affected. The positive correlation between vitamin D and calcium, together with the negative correlation with the Cobb angle, is yet another proof that patients with idiopathic scoliosis should be investigated regularly for these pathologies.
Invasive Treatment Options for Gastro-Esophageal Reflux Disease
Authors: Dumitru Vlad ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   General and Esophageal Surgery Clinic, “Sf Maria” Clinical Hospital, Bucharest, Romania, Hoara Petre ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   General and Esophageal Surgery Clinic, “Sf Maria” Clinical Hospital, Bucharest, Romania,   Petre Hoara, MD, PhD 37-39 Ion Mihalache Blvd., District 1,Bucharest, Romania, 011172 Phone: +40212227201 E-mail: petre_hoara@yahoo.com, Dumitru Daniela ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   General and Esophageal Surgery Clinic, “Sf Maria” Clinical Hospital, Bucharest, Romania, Birla Rodica ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   General and Esophageal Surgery Clinic, “Sf Maria” Clinical Hospital, Bucharest, Romania, Gindea Cristina ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   General and Esophageal Surgery Clinic, “Sf Maria” Clinical Hospital, Bucharest, Romania, Constantinoiu Silviu ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   General and Esophageal Surgery Clinic, “Sf Maria” Clinical Hospital, Bucharest, Romania
Published: November 2022

Reflux disease continues to be one of the most common pathologies in the world. There is much discussion regarding the mechanism of developing and the variety of possible symptoms. In recent years, the use of new technologies, like high-resolution manometry and pH impedance, brought new insights into this disease. Also, there are emerging therapies that are covering the gap between the patients treated with proton-pump inhibitor (PPI) therapy and those who benefit the most from laparoscopic treatment (hiatal hernia, complications of gastroesophageal reflux disease (GERD). Also, most of them are less invasive than a laparoscopic fundoplication.

We present a short review of the treatment options in patients who need more than lifestyle changes and PPI therapy.
Methods of Delivery in Pregnant Women with Lumbar Disc Herniation: A Narrative Review of General Management and Case Report
Authors: Gabriela Paslaru Francesca ,   Neurosurgical Department, Bagdasar-Arseni Clinical Emergency Hospital, Bucharest, Romania, Giovani Andrei ,   Neurosurgical Department, Bagdasar-Arseni Clinical Emergency Hospital, Bucharest, Romania, Iancu George ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Obstetrics and Gynecology Department, Clinical Hospital of Obstetrics and Gynecology Filantropia, Bucharest, Romania, Panaitescu Anca ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Obstetrics and Gynecology Department, Clinical Hospital of Obstetrics and Gynecology Filantropia, Bucharest, Romania,   Anca Panaitescu, Clinical Hospital of Obstetrics and Gynecology Filantropia 11 Ion Mihalache,Bucharest, Romania. E-mail: panaitescu.anca@yahoo.com, Peltecu Gheorghe ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Obstetrics and Gynecology Department, Clinical Hospital of Obstetrics and Gynecology Filantropia, Bucharest, Romania, Mircea Gorgan Radu ,   Neurosurgical Department, Bagdasar-Arseni Clinical Emergency Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: November 2022

Low back pain is a common complaint during pregnancy, affecting approximately half of pregnant women. However, true disc herniation is extremely rare, and the majority of patients heal without surgery. The purpose of this study was to provide an overview of conservative management strategies and delivery modes for pregnant patients suffering from lumbar disc herniation without severe neurologic deficits that would require emergency surgery. We performed a narrative review of the literature using the PubMed database. Thirty-one articles were originally retrieved, out of which 7 met the inclusion criteria, compiling a total of 10 cases of parturient patients with lumbar disc hernia treated conservatively until childbirth. The preferred delivery mode was a Cesarean section, which was performed in 6 out of 10 cases. Two patients developed the cauda equina syndrome, one during a failed induction and the other patient 4 weeks after vacuum extraction. However, the second patient failed to improve after surgery. No patients developed cauda equina syndrome during or after the Cesarean section. Based on limited data, the Cesarean section seems to be preferred compared to vaginal delivery to avoid worsening symptoms and progression to the cauda equina syndrome.
Development of a Knowledge-based Clinical Decision Support System for Multiple Sclerosis Diagnosis
Authors: Hosseini Azamossadat ,   Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Asadi Farkhondeh ,   Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran,   Farkhondeh Asadi Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.E-mail: asadifar@sbmu.ac.ir, Arani Leila Akramian ,   Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Published: November 2022

The diagnosis of multiple sclerosis (MS) is difficult considering its complexity, variety in signs and symptoms, and its similarity to the signs and symptoms of other neurological diseases. The purpose of this study is to design and develop a clinical decision support system (CDSS) to help physicians diagnose MS with a relapsing-remitting phenotype. The CDSS software was developed in four stages: requirement analysis, system design, system development, and system evaluation. The Rational Rose and SQL Server were used to design the object-oriented conceptual model and develop the database. The C sharp programming language and the Visual Studio programming environment were used to develop the software. To evaluate the efficiency and applicability of the software, the data of 130 medical records of patients aged 20 to 40 between 2017 and 2019 were used along with the Nilsson standard questionnaire. SPSS Statistics was also used to analyze the data. For MS diagnosis, CDSS had a sensitivity, specificity and accuracy of 1, 0.97 and 0.99, respectively, and the area under the ROC curve was 0.98. The agreement rate of kappa coefficient (κ) between software diagnosis and physician’s diagnosis was 0.98. The average score of software users was 98.33%, 96.65%, and 96.9% regarding the ease of learning, memorability, and satisfaction, respectively. Therefore, the applicability of the CDSS for MS diagnosis was confirmed by the neurologists. The evaluation findings show that CDSS can help physicians in the accurate and timely diagnosis of MS by using the rule-based method.
Pericarditis as a trigger for Prinzmetal angina – a case report
Authors: Sheibani Hossein ,   Clinical Research Development Unit, Imam Hossein Hospital, Shahroud University of Medical Science, Shahroud, Iran,   Hossein Sheibani, Shahroud University of Medical Sciences, Shahroud, Iran. E-mail: h1a1sheyban@gmail.com, sheybani@shmu.ac.ir https://orcid.org/0000-0003-1632-0511, Javedani Masroor Mojgan ,   Shahid Akbar-Abadi Clinical Research Development Unit, Iran University of Medical Science, Tehran, Iran
Published: November 2022

Prinzmetal angina is one of the causes of acute coronary syndromes, the exact etiology of which is still unknown. Here we introduce a 27-year-old man with no history of cardiovascular disease, with a history of hospitalization due to acute pericarditis in the previous month, who was discharged with a good response to ibuprofen treatment but had clinical and electrocardiographically recurrence of pericarditis with compressive retrosternal chest pain and electrocardiogram (ECG) changes in favor of acute infero-postero-right ventricular (RV) myocardial infarction (MI). Treatment with vasodilator improved compressive retrosternal chest pain and reversed acute myocardial infarction changes completely and left pleuritic chest pain and pericarditis changes in the ECG. Due to the typical chest pain, he was admitted to the emergency room; ECG revealed generalized ST-segment elevation with acute pericarditis pattern again. Acute infero-posterior and right ventricular acute myocardial infarction pattern was also evident. After treatment with nitroglycerin in the Critical Cardiac Unit (CCU), all ECG ischemic changes returned to baseline, and pericarditis remained in all leads. The patient was discharged with non-steroidal anti-inflammatory drugs (NSAIDs), calcium channel blockers, and a good general condition.
Fimasartan ameliorates renal ischemia reperfusion injury via modulation of oxidative stress, inflammatory and apoptotic cascades in a rat model
Authors: Abbas Weaam ,   Department of Pharmacology & Therapeutics, Faculty of Medicine, University of Kufa, Kufa, Iraq, Altemimi Murooj ,   Department of Pharmacology & Therapeutics, Faculty of Medicine, University of Kufa, Kufa, Iraq, Qassam Heider ,   Department of Pharmacology & Therapeutics, Faculty of Medicine, University of Kufa, Kufa, Iraq https://orcid.org/0000-0002-1422-8677, Hameed Ahmed Abdul ,   Department of Pharmacology & Therapeutics, Faculty of Medicine, Jabir Ibn Hayyan Medical University, Najaf, Iraq, Zigam Qassim ,   Department of Pharmacology, Al-Mustaqbal University College, Babylon, Hilla, Iraq, Abbas Lamaan ,   Al-Sadr Medical City, Al-Najaf Health Directorate, Al-Najaf Al-Ashraf, Iraq, Jabir Majid ,   Department of Applied Science, University of Technology, Baghdad, Iraq, Hadi Najah ,   Department of Pharmacology & Therapeutics, Faculty of Medicine, University of Kufa, Kufa, Iraq,   Najah Hadi, Department of Pharmacology & Therapeutics, Faculty of Medicine, University of Kufa, Kufa, Iraq. E-mail: drnajahiraq@gmail.com; drnajahhadi@yahoo.com https://orcid.org/0000-0001-9084-591X
Published: November 2022

Ischemia-reperfusion injury (IRI) can be defined as changes in the functions and structures of the tissues resulting from the restoration of blood after a period of ischemia. This study aimed to assess the potential protective effect of Fimasartan (angiotensin receptor antagonist) in the bilateral renal IRI in male rats through its potential effect on renal functions, modulation of the inflammatory cascade, oxidative stress, and apoptotic effect. The animals were equally assigned into four groups. The sham (negative control) group was exposed to surgical conditions without induction of IRI. The control group was exposed to ischemia by occluding the renal pedicles by clamps for 30 min, followed by restoration of blood for 2h. The vehicle-treated group received dimethyl sulfoxide (DMSO) by intraperitoneal injection (IP) 30 minutes before clamping. Fimasartan-treated group: rats pretreated with Fimasartan a dose of 3 mg/kg IP; this was half hour before occluding the renal pedicles. Animals were then exposed to 30 min ischemia (clamping the renal pedicles) followed by 2h reperfusion by releasing the clamps. Blood samples were collected to examine the levels of serum urea and creatinine. Renal tissue was used to measure the levels of cytokines (TNFα, IL-6) and total antioxidant capacity (TAC). Immunohistochemistry was used to assess the levels of Bax, caspase 3, and Bcl-2. Histopathological analyses were performed to detect the parenchymal injury. The present study shows that pretreatment with Fimasartan improves kidney function through its effects on oxidative stress, cytokines, and apoptotic markers.
The expansion of the role of nurse prescribing in intensive care units in the healthcare system of Iran: a qualitative content analysis
Authors: Naderi Azam ,   School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran https://orcid.org/0000-0001-7755-9257, Abbaszadeh Abbas ,   Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran,   Abbas Abbaszadeh, Department of Medical-surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. E-mail: aabaszadeh@sbmu.ac.ir https://orcid.org/0000-0001-5708-7838, Pazokian Marzieh ,   Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran https://orcid.org/0000-0002-7583-1824, Rohani Camelia ,   Community Health Nursing Department, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran,   Department of Health Care Sciences, Palliative Care Center, Marie Cederschiöld Högskola, Ersta Sköndal Bräcke University College, Stockholm, Sweden https://orcid.org/0000-0002-6456-6586, Jalali Rostam ,   Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran https://orcid.org/0000-0003-1781-9939
Published: November 2022

Intensive Care Unit (ICU) nurses prescribe medication for patients in many countries. However, there is still no evidence on the legitimacy of nurse prescribing roles in the healthcare system of Iran. This qualitative study with 30 experts was conducted to explore the experiences regarding the expanding role of prescribing medication by the ICU nurses. Data were collected through 31 individual semi-structured interviews and analyzed using the conventional content analysis method by MAXQDA 10. One major theme, “applicability of prescribing medication by ICU nurses”, together with three sub-themes of “facilitators”, “potential risks of nurse prescribing” and “the professional pathway”, emerged. The use of successful global experiences, patient-oriented healthcare system policies, current culture and positive professional position of nurses, physician shortage, and high capacity of ICU nurses appeared as facilitators to perform the new role in our context. For the expansion of the new role, different professional pathways such as discussion with physicians and special groups with conflicts of interests, training qualified nurses in this area, and gradual development were proposed by the participants. The next step of the research is to prepare a set of standards for the prescription of medication by the ICU nurses in our context.
Calculating the number of undetected active SARS-CoV-2 infections from results of population-wide antigen tests
Authors: Standl Fabian ,   Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany,   Fabian Standl, Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen Hufelandstr, 55D-45147 Essen, Germany. Phone: +49 201/723-77263; E-mail: Fabian.Standl@uk-essen.de,   Both authors have contributed equally to the manuscript., Kowall Bernd ,   Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany,   Both authors have contributed equally to the manuscript., Frost Anna Katharina ,   Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany, Brune Bastian ,   Medical Direction Communal Emergency Service of the City Essen, Essen, Germany,   Clinic for Trauma, Hand and Reconstructive Surgery, University Hospital Essen, Essen, Germany, Brinkmann Marcus ,   Center for Clinical Trials Essen, University Hospital Essen, Essen, Germany, Dudda Marcel ,   Medical Direction Communal Emergency Service of the City Essen, Essen, Germany,   Clinic for Trauma, Hand and Reconstructive Surgery, University Hospital Essen, Essen, Germany, Oesterling Florian ,   Federal Cancer Registration gGmbH, Bochum, Germany, Jansen Philipp ,   Clinic for Dermatology, University Hospital Essen, Essen, Germany, Jöckel Karl-Heinz ,   Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany, Stang Andreas ,   Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany,   Department of Epidemiology, Boston University, Boston, United States of America
Published: November 2022

Current European research estimates the number of undetected active SARS-CoV-2 infections (dark figure) to be two- to 130-fold the number of detected cases. We revisited the population-wide antigen tests in Slovakia and South Tyrol and calculated the dark figure of active cases in the vulnerable populations and the number of undetected active cases per detected active case at the time of the population-wide tests. Our analysis follows three steps: using the sensitivities and specificities of the used antigen tests, we first calculated the number of test-positive individuals and the proportion of actual positives in those who participated in the antigen tests. We then calculated the dark figure in the total population of Slovakia and South Tyrol, respectively. Finally, we calculated the ratio of the dark figure in the vulnerable population to the number of newly detected infections through PCR tests. Per one positive PCR result, another 0.15 to 0.71 cases must be added in South Tyrol and 0.01 to 1.25 cases in Slovakia. The dark figure was in both countries lower than assumed by earlier studies.
Assessment of the incidence and etiology of nosocomial diarrhea in a medical ward in Iraq
Authors: Hamad Ammar Jabbar ,   Department of Medicine, College of Medicine, University of Kufa, Al-Najaf, Iraq, Albdairi Aseel Jassim ,   Department of Physiology, College of Medicine, University of Kufa, Al-Najaf, Iraq, Alkemawy Samer Nema Yassen ,   Department of Medicine, College of Medicine, University of Kufa, Al-Najaf, Iraq, Khudair Safaa Ali ,   Department of Medicine, College of Medicine, University of Kufa, Al-Najaf, Iraq, Abdulhadi Noor Rafea ,   Department of Medicine, Al Sadar Medical City, Al-Najaf, Iraq
Published: November 2022

This study aimed to detect the incidence, etiology, risk factors, and severity of nosocomial diarrhea among adult inpatients in a medical ward in Iraq. The study was conducted among patients admitted to the medical ward from June 1, 2019, to January 31, 2020, in AL-Sader medical city. The surveillance for nosocomial diarrhea was performed by monitoring every patient in the ward 3 times/week. 1050 patients were admitted to the medical ward in AL-Sader medical city. Of these, 52 patients (mean age 58±12.91 years, range 32 to 80) developed new-onset diarrhea during hospitalization. There was a significant relationship between the severity of diarrhea and age, residence, antibiotic use, including number and duration of antibiotics, immunosuppressive agents (steroids/chemotherapy), duration of hospital stay, level of consciousness, and enema use. Nosocomial diarrhea is a significant clinical problem that complicates about 5% of all admission in the medical ward. Various microorganisms account for nosocomial diarrhea, including E. histolytica, G. lamblia, and Candida. Several risk factors associated with the severe form of nosocomial diarrhea include old age, antibiotic use, immunosuppressive use, and length of hospital stay.
Exploring experiences of psychological distress among Iranian parents in dealing with the sexual behaviors of their children with autism spectrum disorder: a qualitative study
Authors: Masoudi Mojgan ,   Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran, Maasoumi Raziyeh ,   Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran,   Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran,   Raziyeh Maasoumi, Department of Reproductive Health, Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran. Phone: +982161054231; P.O. Box: +981419733171; E-mail: r.masoomie@gmail.com, Effatpanah Mohammad ,   Pediatric Department, Tehran University of Medical Sciences, Tehran, Iran, Bragazzi Nicola Luigi ,   Department of Mathematics and Statistics, York University, Toronto, Canada, Montazeri Ali ,   Academic Center for Education, Culture and Research (ACECR), University of Science and Culture, Tehran, Iran
Published: November 2022

Sexual behavior is influenced by social and communication deficits in autism spectrum disorder (ASD) and is a serious challenge for parents who lack effective strategies for providing sexual education to their children with ASD. The purpose of this study was to explore Iranian parents' experiences of psychological distress in dealing with the sexual behaviors of their children with ASD. This qualitative study was designed following the conventional content analysis approach. Semi-structured and in-depth interviews were conducted with 27 parents of children with ASD aged 8–34 years. All interviews were audio-recorded and transcribed verbatim. The data were collected through purposeful sampling and continued until data saturation. The worries theme was extracted from data interpretation using qualitative content analysis, and this theme entailed four subthemes: 1) sexual vulnerability, 2) unintended social consequences, 3) psychological suffering, and 4) confusion about the future of a child's sex life. This study emphasized the importance of paying attention to parents' concerns about the sexual behaviors of children with ASD. Parents' psychological distress is a major obstacle to proper coping with sexual behaviors, and using coping strategies may help reduce psychological distress in parents of children with ASD. Therefore, it is necessary to design, implement, and evaluate culture-appropriate educational programs to address parents' concerns regarding the sexual health of a child with autism.
Management of percutaneous treatment of aorta coarctation diagnosed during pregnancy
Authors: Cherpak Bogdan Volodymyrovych ,   Pediatric Cardiology and Cardiosurgery Department, National Amosov Institute of Cardiovascular Surgery NAMS, Kyiv, Ukraine,   Bogdan Volodymyrovych Cherpak, Pediatric Cardiology and Cardiosurgery Department, National Amosov Institute of Cardiovascular Surgery NAMS, Kyiv, Ukraine. E-mail: bcherpak@gmail.com, Davydova Yulia Volodymyrivna ,   Obstetrics Department for Extragenital Pathology in Pregnant Women, Institute of Pediatrics, Obstetrics and Gynecology NAMS, Kyiv, Ukraine, Kravchenko Vitalii Ivanovich ,   Department of Surgical Treatment of Aortic Pathology, National Amosov Institute of Cardiovascular Surgery NAMS, Kyiv, Ukraine, Yaschuk Natalia Sergiivna ,   Pediatric Cardiology Intervention Department, National Amosov Institute of Cardiovascular Surgery NAMS, Kyiv, Ukraine, Siromakha Sergii Olegovich ,   National Amosov Institute of Cardiovascular Surgery NAMS, Kyiv, Ukraine, Lazoryshynets Vasil Vasylovych ,   National Amosov Institute of Cardiovascular Surgery NAMS, Kyiv, Ukraine
Published: November 2022

Management of coarctation of the aorta (CoA) during pregnancy is complicated by increased procedural risks to the pregnant woman and her fetus. The aim of this research was to analyze 10-years of experience of CoA treatment diagnosed during pregnancy. During 2010–2020 we performed percutaneous stents implantations (SI) in 4 women during 15–23 weeks of pregnancy and in 6 women 48 hours – 5 years after delivery. In all presented cases, successful CoA repair was achieved. There was a significant decrease of peak-to-peak invasive systolic pressure gradient across the CoA (60.0±31.2 and 11.8±7.3 mmHg, p=0.001) and mean noninvasive systolic arterial pressure (163.0±46.2 and 120.5±9.2 mmHg, p=0.01) after SI. All percutaneously treated women during pregnancy (n=4) delivered healthy full-term babies. At follow-up (from 2 months to 10 years), all 10 women are alive without significant Doppler gradient across CoA with no signs of aortic aneurysm formation. To the best of our knowledge, we presented the largest published cohort of CoA percutaneous treatment during pregnancy. We categorized our experience in managing aortic coarctation diagnosed during pregnancy in one algorithm. Our experience demonstrates that excellent maternal and neonatal pregnancy outcomes can be obtained in women after CoA percutaneous repair, diagnosed during pregnancy. An aortic stent implantation is effective and safe for both mother and fetus.
Verglichene Körper. Normieren, Urteilen, Entrechten in der Vormoderne
Authors: Aust Cornelia
Published: November 2022

Menschliche Körper sind in vielfältige Praktiken eingebunden, darunter solche der Wahrnehmung und Herrschaft. Körper wurden normiert, beurteilt, häufig auch entrechtet. Die Beiträge in diesem Band gehen der Frage nach, welche Rolle Praktiken des Vergleichens in Bezug auf den Körper spielten. Wurden Körper oder bestimmte körperliche Merkmale verglichen? Waren Körperpraktiken, Körpermerkmale oder Körperteile Variablen, die dazu dienten, einzelne Frauen und Männer oder Menschengruppen miteinander zu vergleichen? Zugleich fragen die Autor*innen für den Zeitraum des 12. bis 19. Jahrhunderts nach der Materialität und Wahrnehmung von Körpern in ihrer Verbindung mit Konzepten von gesellschaftlicher Ordnung und Hierarchie. Die Beiträge zeigen, dass die Bedeutung von Körpern und Körperlichkeit für die Bildung von Ordnung(en) im Laufe der Vormoderne zunahm, ohne dass sich jedoch ein linearer Verlauf beschreiben lässt.
Brain metastasis from a thoracic myxofibrosarcoma: A case report and literature review
Authors: Ferreira Neto Otávio da Cunha , Bezerra Roberto Borges , Silva Rhuann Pontes dos Santos , Silva Melissa Helena Rodrigues , de Alencar Neto Joaquim Fechine , Lopes Arthur José Maia
Published: November 2022

Background:

Myxofibrosarcoma (MFS) is a type of sarcoma that mainly affects elderly people; it represents only 5% of all sarcomas and shows no line of differentiation. Intracranial MFS is a rare condition. At present, limited data exist regarding brain metastasis from MFS. This article reports a case of MFS and reviews the literature regarding MFS metastasis.

Case Description:

We report a case of brain metastasis from chest wall MFS. The patient was diagnosed with an anterior thoracic MFS and underwent surgery and radiotherapy. One year later, he noticed a tumor on his left shoulder, and more than 1 year thereafter, bilateral lung metastasis was observed. Twelve months after lung metastasis, he presented to the emergency department and underwent contrast-enhanced magnetic resonance imaging, which demonstrated a left frontal tumor suggestive of brain metastasis. Since the main hypothesis was a sarcoma metastasis at the location close to the left motor area, and the patient had a good Karnofsky performance scale, the patient underwent neuronavigation-guided surgery. After surgery, the patient developed Grade III hemiparesis and aphasia. Brain tumor histopathology confirmed a malignant neoplasm with osteosarcomatous differentiation and metastasis from MFS.

Conclusion:

We report a rare case of MFS metastasis. To the best of our knowledge, this is the eighth case of intracerebral metastasis from MFS.
The future of artificial intelligence in neurosurgery: A narrative review
Authors: Iqbal Javed , Jahangir Kainat , Mashkoor Yusra , Sultana Nazia , Mehmood Dalia , Ashraf Mohammad , Iqbal Ather , Hafeez Muhammad Hassan
Published: November 2022

Background:

Artificial intelligence (AI) and machine learning (ML) algorithms are on the tremendous rise for being incorporated into the field of neurosurgery. AI and ML algorithms are different from other technological advances as giving the capability for the computer to learn, reason, and problem-solving skills that a human inherits. This review summarizes the current use of AI in neurosurgery, the challenges that need to be addressed, and what the future holds.

Methods:

A literature review was carried out with a focus on the use of AI in the field of neurosurgery and its future implication in neurosurgical research.

Results:

The online literature on the use of AI in the field of neurosurgery shows the diversity of topics in terms of its current and future implications. The main areas that are being studied are diagnostic, outcomes, and treatment models.

Conclusion:

Wonders of AI in the field of medicine and neurosurgery hold true, yet there are a lot of challenges that need to be addressed before its implications can be seen in the field of neurosurgery from patient privacy, to access to high-quality data and overreliance on surgeons on AI. The future of AI in neurosurgery is pointed toward a patient-centric approach, managing clinical tasks, and helping in diagnosing and preoperative assessment of the patients.
On the problem of national peculiarities in epos
Authors: Егиазарян А.К.
Published: November 2022

В статье рассматриваются проблемы национального своеобразия народных эпосов и связанные с этим вопросы типологии. Автор исходит из того, что проблема до сих пор не рассматривалась достаточно глу- боко, хотя национальное своеобразие эпосов кажется очевидным. Но огромное разнообразие эпических памятников ставит перед исследователем массу вопросов. Первый из них – это типология эпосов. Здесь существуют различные подходы. Точка зрения автора близка к взглядам русского ученого Е. М. Мелетин- ского и английского ученого Сесиля Боуры. Автор мировые эпические памятники делит на две большие группы – архаические и средневековые. И уже то, к какому типу относится эпос данного народа, является показателем национального своеобразия. Ибо в культуре каждого народа есть черты, которые ее связы- вают или с архаикой, или со Средневековьем. Но в этих группах тоже эпосы разных народов отличаются друг от друга достаточно существенно. Автор сравнивает три памятника, которые, созданы или сфор- мированы в средние века – армянский эпос «Давид Сасунский», французский эпос «Песнь о Роланде» и испанский эпос «Песнь о моем Сиде». «Давид Сасунский» вобрал в себя множество мифологических сю- жетов, возникших в древнейшие времена, но переосмысленные с точки зрения средневековых традиций и ценностей армян. Французскaя и испанская эпические поэмы почти полностью лишены мифического элемента. Герои трех памятников действуют как рыцари, но при этом армянский Давид Сасунский поня- тия не имеет о правилах рыцарского поведения, которые были так важны в средневековой Европе, а Сид и Роланд, каждый по-своему, верны правилам рыцарского поведения. Притом, поступки Сида и Роланда очень часто выдают разное понимание ими рыцарских правил, что было характерно для национальных культур Испании и Франции
Some issues of genesis research and poetics of the Tatar version of the «Son of Kur»
Authors: Мухаметзянова Л.Х.
Published: November 2022

Статья посвящена исследованию эпического произведения под названием «Кур углы». Актуальность данного исследования обусловлена отсутствием комплексного аналитического исследования генезиса и поэтики татарской версии дастана. Цель статьи – исследовать татароязычный книжный эпос «Кур углы» как памятника, способного хранить поэтические традиции творческого сознания этноса. Задача, вытека- ющая из поставленной цели – исследовать различные татарские варианты дастана на сюжет о Кур углы; описать общие структурно-содержательные особенности текстов; выявить общее и различие между тра- диционным тюркским героическим и татарским книжным эпосом на данный сюжет. В статье использова- ны сравнительно-исторический, историко-типологический, текстологический методы исследования. Национальные версии дастана о Кур условно подразделяются на западные (аджарские, турецкие, азер- байджанские) и восточные (туркменские, узбекские, казахские, таджикские) версии. Немало восточных и западных версий были записаны из уст знаменитых бахши в музыкальном исполнении. На анализе существующих рукописных и изданных татарских текстов, относящихся к XIX в., в статье прослежены отдельные мотивы знаменитого эпоса о Кур углы, проведены параллели между общетюркским героиче- ским эпосом, выявлены особенности татарской версии «Кур углы». В отличие от западных и восточных версий сюжетная система татарских вариантов компактнее, и они у татар не исполнялись ашугами, а рас- пространялись в книжной форме. На определенном этапе формирования книжной разновидности эпоса дастан «Кур углы» знаменателен как произведение, удовлетворявшее потребности народа в письменной литературе.
Some comparative-typological features Batyr in the epos of the Tatar people
Authors: Гайфутдинова Р.М.
Published: November 2022

Объектом статьи «Некоторые сравнительно-типологические черты батыра в эпосе татарского народа» является образ главных героев в эпических сказаниях татарского народа. В эпических сказаниях батыр – это, прежде всего, представитель простого народа, который символизирует его вековые идеи и чаяния. По- другому, данного типа героя называют народным. Так как он обогащен мировоззренческими взглядами, политическими убеждениями народа. И среда эпоса символически стала охарактеризовать героя как при- мер, идеал подражения. Прослеживая эволюцию эпической биографии главного героя и его богатырских поступков на сравнительно-типологической и историко-типологической основе, выявляются ведущие мотивы создания образа батыра с национальным характером. В современном эпосоведении понятие «на- родный герой» употребляется как харизматический символ национальной идентичности. Реконструкция портретной характеристики народного батыра идет через анализ общеэпических приемов. Такие мотивы как чудесное рождение, добывание богатырского коня и оружия, магическая неуязвимость определяют «лицо» каждого народного героя. Также акцентируется внимание на трансформации роли главного героя с его функциональным назначением. Иногда народный герой отличается многофункциональностью, кото- рый определяется исходом развивающихся событий эпоса.
Question about historicism of epic folklore (along the ancient Silk Road)
Authors: Соегов М.
Published: November 2022

В свете современных научных знаний, накопленных за последние годы, рассматриваются специфиче- ские вопросы отражения маршрутов древнего Шелкового пути в туркменском эпическом народном твор- честве в сравнении с аналогичными фактами из фольклора и литературы некоторых других народов. Все туркменские любовно-фантастические дестаны (романы), названия которых содержат личные имена возлюбленных («Лейли и Меджнун», «Юсуп и Зулейха», «Гюль и Билбил», «Зохра и Тахир», «Шах- сенем и Гариб» и др. Общее число подобных произведений доходит до 25), пропитаны духом странствий в далекие края, где главный герой подвергается cуровым испытаниям в прочности своих чувств к возлю- бленной, проходя через ужасные приключения с дивами, джиннами, пери и другими сверхъестественны- ми персонажами. Несмотря на то, что в любовно-фантастическом дестане «Гюль и Сенубер» чувствуется сильное вли- яние арабских сказок из цикла «Тысяча и одна ночь», а также местных туркменских сказок, изложение событий в нем начинается именно с рассказа о том, что отец главного героя Сенубера, Хуршид-падишах является правителем города (страны) под названием Чин (т. е. Китай). Автор свое произведение закан- чивает также тем, что после многочисленных приключений и мытарств в разных странах, в том числе в шехри-Шебистане (городе-стране Мрака), Сенубер со своей возлюбленной Гюль возвращается в род- ной город (страну) Чин (Китай) на постоянное жительство. В туркменском анонимном любовном дестане «Хюрлукга и Хемра» наблюдается обратный маршрут следования главного героя из Египта (Misr / Müsür) в Китай (Çyn-Maçyn) и обратно. В статье данный сюжет преследуется полностью.
Translation methods of the epic formulas of the universe from Yakut into French (based on the olonkho “Eles Bootur” by P. V. Ogotoev)
Authors: Шапошникова В.И.
Published: November 2022

Статья посвящена исследованию эпических формул мироздания в олонхо «Элэс Боотур» П. Оготоева (в оригинале и в переводе на французский язык). Цель работы – сопоставление якутского и французского вариантов эпических формул мироздания для выявления способов их перевода с якутского на француз- ский язык. Показано, что в оригинале и в переводе олонхо имеются вертикальная (контактная простая и сложная) и горизонтальная (контактная простая и сложная) аллитерации. В аллитерации преобладает анафориче- ский повтор. Одинаковые синтаксические конструкции в эпических формулах образуют ритмико-синтаксические параллелизмы, состоящие из нескольких стиховых строк, создают ритмическую организацию эпических формул и придают олонхо необычайную торжественность. Параллельные конструкции способствуют созданию возрастающей градации. Градационный эффект обеспечивается выбором близких по значению слов, синонимов и их расположением в параллельных конструкциях. Основой градуирования являются перечисляемые признаки слов, которые располагаются в порядке их возрастания. Во французском переводе больше количество слов и слогов в стихотворной строке, чем в якутском оригинале. Используется множество переводных трансформаций (замена, добавление, перестановка чле- нов предложения, перестройка стиховых строк). Для передачи на французский язык аллитерации исполь- зуются определенные и неопределенные артикли в начале стиховых строк и порядок слов в параллельных конструкциях. Для передачи градационного эффекта выбраны слова, близкие по значению, учитывается их расположение в параллельных конструкциях
Peculiarities of the Russian epic folklore in the North-Eastern Yakutia
Authors: Чарина О.И.
Published: November 2022

В статье рассматриваются особенности бытования русского эпического фольклора, зафиксированного на Колыме в Якутии. Для анализа используются варианты текстов, собранных Д. И. Меликовым в 1893 г.; В. Г. Богоразом в 1894 г.; а также – материалы, опубликованные в сборниках «Русская эпическая поэзия Сибири и Дальнего Востока», «Фольклор Русского Устья» [4, 6]. Для примера рассматривается былина о Добрыне Никитиче и Змее. Выясняется, что уже записи вариантов XIX в. разнятся. Так, в меликовском ва- рианте Змей мужского рода, в варианте Богораза Змеинища – женского рода. Происходит замена мотивов, например, когда вместо мотива «жары меженные» появляются в «жары крестовские». Совершенно очевидно, что былины Колымы имеют непосредственную связь с произведениями фоль- клора, бытовавшими на Русском Севере Европейской части России. Эти произведения фольклора отли- чает региональное своеобразие, так как они имеют отличие от вариантов былины, зафиксированных на Индигирке, о чем говорит Л. Н. Скрыбыкина [8]. Постепенно эпический фольклор был утрачен. Об этом свидетельствуют записи фольклора в 1982 г., когда часть вариантов приводились в прозе, отсутствовал ряд образов, мотивов, концовка произведения. Автор ссылается на ряд своих работ по данной тематике. Влияние якутского языка в былинах не про- явилось, хотя оно заметно в исторических песнях
Alkyne Polymers from Stable Butatriene Homologues: Controlled Radical Polymerization of Vinylidenecyclopropanes
Authors: Wu Bin , Ding Qian-Jun , Wang Zheng-Lin , Zhu Rong
Published: November 2022

Controlled polymerization of cumulenic monomers represents a promising yet underdeveloped strategy towards well-defined alkyne polymers. Here we report a stereoelectronic effect-inspired approach using simple vinylidenecyclopropanes (VDCPs) as butatriene homologues in controlled radical ring-opening polymerizations. While being thermally stable, VDCPs mimic butatrienes via conjugation of the cyclopropane ring. This leads to exclusive terminal-selective propagation that affords a highly structurally regular alkynebased backbone, featuring complete ring-opening and no backbiting regardless of polymerization conditions.
THE LOSS OF STATE-OWNED ENTERPRISE (BUMN) AS NOT STATE LOSS IN SEPARATION PRINCIPLE PERSPECTIVE
Authors: Ambarwati Siska , Yuliati Yuliati , Widhiyanti Hanif Nur
Published: November 2022

The study aims to analyze, first, the BUMN sub-holding loss as a state loss and secondly, the responsibility of the BUMN holding company for the BUMN sub-holding loss. There is a dualism in the conception of state assets that are separated from BUMN in Indonesian laws and regulations. The research methods was normative legal research with a statutory approach and a case approach. The shares of BUMN sub-holding don’t come from the state but come from the BUMN and also the public. The capital investment which it does by the BUMN holding company to the BUMN sub-holding doesn’t make the BUMN sub-holding become a BUMN. In the Group Company, the principle of a separate entity continues to apply which leads to the principle of limited liability holding as a subsidiary shareholder. However, if BUMN as the majority shareholder has the right to actively intervene and it is proven that there is control of the company, then the principle of piercing the corporate vision can be applied. So the BUMN holding company must be responsible for BUMN sub-holding because of the control carried out by these BUMN holding companies. The results show that the BUMN sub-holding loss isn’t state loss.
THE SELF REGULATION ON PEER TO PEER (P2P) OF LENDING INDUSTRY IN INDONESIA AS PROBLEMS AND PROSPECTS
Authors: Fajar Mukti , Setianingrum Reni Budi
Published: November 2022

The purpose of this research is to find out that the industrial revolution 4.0 has had a significant impact, especially in the use of technology and the internet in daily human activities, both in personal life and in economic activities. This study used a normative legal research method that examines various legal theories related to financial technology both in Indonesia and other countries. The P2P lending service carries out business activities by providing, managing, and operating money-borrowing services by utilizing information technology as a liaison. Peer to Peer (P2P) Lending in Indonesia is regulated in POJK No. 77/POJK.01/2016 concerning Information Technology-Based Lending and Borrowing Services. This regulation is the basis for the implementation of P2P Lending business activities or online borrowing, which is one type of fintech, including regulations regarding supervision carried out by the Financial Services Authority (OJK) on the implementation of these business activities. However, in practice, lending by P2P Fintech has attracted a lot of controversies because there are still many problems, including interest arrangements, the rise of illegal fintech applications and also the weakness of consumer protection where these things have not been fully addressed and regulated by POJK No. 77/POJK. 01/2016.
THE CONSTRUCTION OF THE VICE PRESIDENT'S AUTHORITY IN INDONESIA'S STATEMENT SYSTEM
Authors: Widayati Widayati , Kusriyah Sri , Winanto Winanto
Published: November 2022

The 1945 Constitution of the Republic of Indonesia stipulates that the President and Vice President are directly elected by the people. The position of the Vice President is at the level below the President. The authority of the Vice President is not clearly and unambiguously regulated in the 1945 Constitution of the Republic of Indonesia or in the laws and regulations below it. As an assistant to the President, the authority of the Vice President is highly dependent on the President. The Vice President's authority will only appear when the President is absent. The authority of the Vice President in Indonesia's constitutional history varies from one to another. For the division of authority between the President and the Vice President, as well as clarity on the authority of the Vice President, it is necessary to have a law regulating the presidential institution. The law on the presidential institution will later serve as the legal basis for the President to share authority with the Vice President. With the division of authority, there will be clarity as to what is the authority of the Vice President, so that when a problem occurs, it can be resolved quickly and thoroughly, without throwing responsibilities at each other. The clarity of the division of authority will also greatly assist the DPR in carrying out its supervisory function, and for the public to assess the performance of the Vice President.