bluuebunny/crossref_metadata_2025 huggingface dataset:
Creative Thinking about God and Respect for Christian Identity
Authors: Gutowski Piotr
Published: June 2023

In the article I refer to the philosophy of William Hasker and his proposal to reconcile respect for the basic dogmas of Christianity with the contemporary standards of knowledge and the needs of people today.

In the first part I analyse Hasker’s view on the idea of Christian philosophy. Since he assumes the truthfulness of the main doctrines of Christianity, he is not opposed to being referred to as a Christian philosopher, but neither is he enthusiastic about this name. This attitude is the result of his conviction that the state of absolute neutrality is not possible in philosophy and that regardless of the views accepted as true by a given thinker the requirement for good philosophy is fairness and evaluating all perspectives and beliefs for their internal coherence and their correspondence with the evidence. Therefore, Hasker first tries very carefully to reconstruct positions different from his own and to track down various difficulties in them, especially contradictions. In my opinion, however, the objection of self-contradiction is ineffective when applied to philosophical positions which, as a rule, use vague concepts. The same applies to the claim that these positions are contradictory to evidence, because one of such vague notions is also the notion of evidence. That is why philosophical claims have the extraordinary ability to persist in life or unexpectedly revive after being considered definitively dead. It does not follow from this that one cannot convincingly justify one’s position using less formal criteria. 

In the second part I focus on the rhetorical device used by Hasker to make his concept of God more attractive. He suggests that we should shape our concept of God based on our idea of a great man, i.e. one who educates children to live independently and is able to effectively and fairly manage large groups of people. Leaving aside the accusation of anthropomorphism, the question arises about the epistemic value of this image, which is not universal, changes over time and depends on the conditions in which people live. The content of this image proposed by Hasker isn’t also consistent with the idea of the God of Christian orthodoxy, which is dominated by traditional rather than open theism. This is where the problem of linking creative thinking and respect for Christian identity arises. Regardless of the opinion that open theism has among traditional theists, Hasker supports the concept of a strong Christian identity determined by a universally recognized creed. I propose to treat this identity a little more flexibly.
Co powinno interesować filozofa w religii?
Authors: Gutowski Piotr
Published: June 2023

Inspiracją do napisania niniejszego artykułu były rozdziały V–VII książki Ryszarda Kleszcza Logika, metafilozofia, wszechmoc. Siedem studiów filozoficznych (2021), dotyczące tej części metafizyki, którą w terminologii scholastycznejokreślano jako filozofię Boga, a obecnie umiejscawia się ją w obrębie teologii filozoficznej lub filozofii religii. Koncentruję się na trzech pytaniach: 1) jak odróżnić badania w zakresie filozofii religii od badań w naukach o religii; 2) czy typowe dla znacznej liczby filozofów religii ograniczanie badań do monoteizmu w największych religiach świata, a w kwestiach bardziej szczegółowych do chrześcijaństwa, można przekonująco uzasadnić bez ujawniania ich własnych przekonań w sprawie religii; 3) czy klasyczny teizm stanowi właściwą artykulację chrześcijańskiego znaczenia słowa „Bóg”. W odpowiedzi na pierwsze pytanie twierdzę, że filozofem religii jest ten, kto bezpośrednio lub pośrednio zajmuje pozytywne lub negatywne stanowisko w sprawie kognitywnego charakteru, a zwłaszcza prawdziwości (Kleszcz wolałby powiedzieć: „uzasadnienia”) wierzeń czy doświadczeń religijnych. Na drugie pytanie, inaczej niż Kleszcz, odpowiadam negatywnie: ujawnienie przez filozofa własnego stosunku do religii nie niweczy ideału obiektywności, natomiast promuje uczciwość wobec czytelników i eliminuje pewien rodzaj teoretycznej hipokryzji spotykany u zwolenników filozofii uprawianej w sposób rzekomo neutralny względem własnych przekonań. Moja odpowiedź na trzecie pytanie jest także negatywna. Potrzebna jest nam dzisiaj mniej zachowawcza, odważniejsza w swoich roszczeniach filozofia religii niż ta proponowana przez Ryszarda Kleszcza — taka mianowicie, która naśladuje sposób uprawiania filozofii przez dawnych mistrzów, np. przez św. Tomasza z Akwinu, polegający na poszukiwaniu filozoficznych podstaw dla chrześcijaństwa, a nie taka, która uznaje wyniki ich ustaleń, np. w kwestii natury Boga, za zasadniczo ostateczne, a korygowalne jedynie w drobnych szczegółach.
Acute esophageal necrosis as a result of taking herbal Medicine
Authors: Jalalabadi Narjes zarei , Khajavirad Nasim , Parsa Samaneh , Karimpour reyhan Sahar
Published: June 2023

Nowadays People use herbal medicines to try to maintain or improve their health but sometimes they cause side-effects and Some herbal drug may also interact with medication. We reported a 37 -year-old man who presented to the emergency department with sever watery diarrhea, vomiting, dysphagia, bicytopenia, renal failure and Acute esophageal necrosis, also known as black esophagus which is a rare syndrome characterized by a striking diffuse circumferential black appearance of the esophageal mucosa that universally affects the distal esophagus, 2-days after use of herbal drug named suranjan . Suranjan is a herbal formulation used to treat Rheumatoid arthritis
Kimura Disease: a Case Report in an Unlikely age group
Authors: Patel Reena , Maheshwari Aradhita , Gawali Vijaykumar
Published: June 2023

Kimura disease is a rare chronic inflammatory disorder of unknown etiology. The disease is primarily seen in young Asian males and is characterized by painless subcutaneous swelling. It is often accompanied by renal involvement, predominantly manifesting as nephrotic syndrome. We describe a case of Kimura disease in a 69-year-old Indian male, presenting with left postauricular swelling. Clinical and histopathological characteristics are described along with a brief review of the literature
Efeitos da pandemia do novo coronavírus no serviço de atendimento móvel de urgência (SAMU) nas ocorrências em uma cidade do interior de Goiás
Authors: Rodrigues Maria Paula Borges , Silva Anderson Cândido Costa , Duarte Gabriela Pereira , Pitanga Karla Karoline , Traboulsi Lucca Sahium , Silva Constanza Thaise Xavier
Published: June 2023

Objetivo: descrever os efeitos da pandemia do novo coronavírus realizadas pelo serviço de atendimento móvel de urgência (SAMU) em Senador Canedo-Goiás no período de 2019-2020. Métodos: Trata-se de um estudo ecológico descritivo, tomando como fonte de informação os boletins de atendimentos do SAMU do respectivo município, referentes ao período de janeiro de 2019 a dezembro de 2020. Foram calculadas as frequências absolutas e relativas das variáveis selecionadas e calculado o teste qui-quadrado com nível de significância de valor 5% (p< 0,05). Resultados: No ano de 2019, foram registradas 1.078 ocorrências, enquanto no ano de 2020 1.705 atendimentos, evidenciado uma ascensão no número de chamados entre os anos. A maioria dos atendimentos eram do sexo masculino (2019-2020 - 59,4%) na faixa etária entre 19 a 45 anos (2019-2020 - 36,3%). O principal local de ocorrência, foi em domicílio (2019-2020 - 45,9%), no turno vespertino (2019-2020 - 34,1%) e as maiores ocorrências foram realizadas aos finais de semana (2019-2020 - 32,1%). O principal tipo de ocorrência se deu por socorro em ambos os anos (2019 - 90,5%; 2020 - 79,6%), embora a remoção/transporte apresentou uma demanda significativa no ano de 2020 (2019 - 9,5%; 2020 - 20,4% - p= ˂0,0001). O principal motivo de atendimento foram por causas clínicas (2019 - 19,5%; 2020 - 28,5% - p= 0,914), seguido pelas causas externas (2019 - 15,3%; 2020 - 26,6% - p= ˂0,0001). Conclusão: observou-se que a pandemia influenciou significativamente no aumento das ocorrências no ano de 2020, elevando o número de remoção/transporte, causando impacto no serviço de saúde e espera-se que os dados inéditos da casuística obtida possam servir de substrato para o planejamento e execução de medidas voltadas para a melhoria da assistência à saúde.
El papel de los significantes y los afectos en la teoría populista
Authors: Cadahia Luciana
Published: June 2023

Este artículo es una reflexión acerca del populismo, siguiendo el derrotero marcado por Ernesto Laclau. En la visión del autor argentino, del populismo se puede tener una visión positiva, no la de la ciencia política eurocéntrica que descalifica al populismo latinoamericano asimilándolo a lo antidemocrático, dictatorial, al autoritarismo y a la democracia plebiscitaria, dispuesta a pasar por encima de las instituciones. Se propone una teoría renovada del populismo, que hace referencia a las luchas populares por la igualdad y los derechos. El rechazo del populismo es, entonces, rechazo del pueblo. Se trata de vivir la República como iguales, en libertad. En esta visión, el populismo no tiene nada que ver con los movimientos en auge como los de Trump, Bolsonaro, Erdogan o Vox. En el texto se hace especial énfasis en el tema de los afectos, dimensión esencial del ámbito político
Economía circular: una aproximación a su origen, evolución e importancia como modelo de desarrollo sostenible
Authors: Espinoza H. Andy
Published: June 2023

Aunque los orígenes de la economía circular (EC) aparecen formalmente en diversas disciplinas y corrientes de pensamiento desde los años setenta, los resultados evidencian que la economía ambiental y ecología industrial fueron determinantes para impulsar su desarrollo. Se estima que la aplicación de la EC impactaría de manera positiva el PIB global en un 1.1%, potenciando la creación de empleos, una mayor resiliencia de las economías y contribuir con las metas trazadas de la agenda 2030. Esta investigación tiene como propósito mejorar la comprensión acerca de los antecedentes e importancia creciente de la EC como modelo de desarrollo sostenible.
Estimación de la eficiencia de las empresas de servicios públicos domiciliarios en Colombia
Authors: Rodríguez Guevara David , Restrepo Giraldo Fred , Trespalacios Alfedo
Published: June 2023

La administración de las empresas de servicios públicos debe velar por el cumplimiento de su demanda, logrando que los recursos financieros cubran los costos y permitan lograr dividendos para sus propietarios. Este trabajo propone una metodología para medir la eficiencia de las empresas de servicios públicos en Colombia, a través de una frontera estocástica, considerando información desde 2014 hasta 2018 de 44 empresas que presentan un ranking de eficiencia de 39% en los recursos de estas empresas.
Unexpected epileptogenic effect of lethal doses of pentobarbital: a case report
Authors: Giudicelli-Bailly Amélie , Badia Chiara Della , Augsburger Marc , Quintard Hervé , Giraud Raphaël , De Stefano Pia
Published: June 2023

Background: Barbiturate poisoning is rare but potentially fatal. Case Report: We reported a case of barbiturate poisoning in a 28-year-old woman who recovered from lethal pentobarbital deliberate self-poisoning. The initial blood pentobarbital concentration was 61 mg/L, corresponding to a potentially lethal dose. Despite the ingestion of a high dose of pentobarbital, the electroencephalogram revealed an unattended pattern compatible with possible nonconvulsive status epilepticus. Following resuscitation maneuvers, appropriate care, and antiseizure medication, the patient awakened after 7 days. The evolution was excellent without neurological deficits at 2 months.Conclusion: Despite the expected and known effects of high-dose pentobarbital in reducing and suppressing cortical activity in the brain, the present case demonstrates that lethal dose of pentobarbital may have an epileptogenic effect. Our hypothesis was that the mechanism of the origin of such a picture is a relatively abrupt decrease in toxic doses of pentobarbital, resulting in a withdrawal phenomenon.
ACESSIBILIDADE E HIBRIDISMO INFORMACIONAL
Authors: Nhacuongue Januário Albino
Published: June 2023

O problema da acessibilidade de pessoas com deficiência ficou agudizado com a pandemia do COVID-19. Atualmente, a Web é a principal tecnologia para o acesso à informação e utilização de serviços, e a falta desse acesso pode causar consequências graves. O objetivo deste trabalho era avaliar a acessibilidade dos sítios dos 645 municípios do Estado de São Paulo, com base nas diretrizes para conteúdo Web, e utilizando o software Avaliador e Simulador de Acessibilidade em Sítios (ASES). Dessa forma, procurou-se responder aos seguintes questionamentos: em que níveis de promoção de acessibilidade os municípios do Estado de São Paulo impulsionam o princípio da inclusão? Como potencializar os ganhos do hibridismo informacional na Web com base na promoção da acessibilidade? Para responder às questões, fez-se uma pesquisa bibliográfica e documental. Como resultados, verificou-se que 547 sítios tinham 34944 erros de marcação, 469 tinham 2235 erros de comportamento, 548 tinham 40397 erros de conteúdo, 133 tinham 1 erro de apresentação e 362 tinham 766 erros nos formulários. No geral, os órgãos analisados preocupam-se com a acessibilidade, mas os problemas identificados apontam para obstáculos que ainda precisam ser superados. Conclui-se que o primeiro passo para potencializar os ganhos do hibridismo informacional na Web com base na promoção da acessibilidade é reconhecer que a atual estrutura social é caracterizada pela concomitância entre híbridos de natureza e cultura diferentes, com actantes humanos e não humanos. O segundo passo é mapeá-los para compreender e mitigar o impacto de suas ações.
Ética y ejercicio de la ciudadanía
Authors: Simons Camino Alberto
Published: June 2023

Este libro tiene como objetivo mostrar que la ética representa primordialmente una forma de pensar, de actuar e intervenir sobre la realidad, sobre los otros seres humanos y sobre uno mismo para lograr una manera de buen vivir —sumak kawsay—, entendida como una existencia digna, cuyo valor fundamental es el respeto por la vida, la naturaleza y de realizarse en comunidad. Alberto Simons Camino busca impulsar la reflexión crítica sobre la importancia, la necesidad y conveniencia de la ética para la persona misma y para cualquier forma de convivencia, sobre todo en la realidad del Perú de hoy.
Análisis económico del derecho
Authors: Bullard G. Alfredo
Published: June 2023

Estudiar derecho sin analizar sus consecuencias es como estudiar medicina sin saber si un medicamento matará o curará al paciente. El derecho es más que la norma o su mera aplicación: es también su consecuencia, pero mucha de la ciencia jurídica tradicional no se plantea estos temas y se distrae en discusiones dogmáticas. El análisis económico del derecho -que regula las conductas- pretende ser una teoría de conducta y es un intento, entre muchos otros disponibles, para tratar de responder preguntas conceptuales relevantes. Para ello toma prestados de la economía su método y aproximación. El usar el método y aproximación de la que es quizás la reina de las ciencias sociales permite descubrir aspectos del derecho que, paradójicamente, no pueden ser descubiertos usando solo el derecho.
Tratado de la venta
Authors: Castillo Freyre Mario
Published: June 2023

En esta obra se abordan temas básicos. El primero corresponde a un análisis del concepto del contrato de compraventa propiamente dicha, que incluye además uno comparativo entre la compraventa y otros contratos y figuras jurídicas afines. El segundo tema es el estudio de los elementos esenciales de la compraventa, como el bien y el precio, así como las fundamentales obligaciones del vendedor y el comprador.
Grupos de poder y derecho en el Perú : el caso de las industrias harinera y oleaginosas
Authors: Flint Blanck Pinkas
Published: June 2023

Metodológicamente toda la obra está estructurada como un universo que partiendo de lo general: el poder, su aplicación a la economía, se va deslizando hacia una realidad concreta donde son ubicados como actores económicos los grupos de la industria harinera y oleaginosa. Desde tal perspectiva Flint, medirá y precisará su condición de grupo económico con poder; es decir de acción e influencia determinante en las políticas económicas del Estado, tomando en cuenta sobre todo, su representatividad estructural como grupo en términos de organización, inversiones o diversificación, características de los grupos económicos en el Perú. El análisis del poder de los grupos económicos perfila evolutivamente la composición, variaciones y alianzas operadas por estos grupos. Así, el estudio lleva a observar fenómenos tales como la concentración industrial, calificada como un componente útil para medir la ubicación y el poder de un determinado sector. Como es obvio, este criterio facilitará la observación de una estructura empresarial en concreto: las harineras y oleaginosas, que serán calificadas como duopólica, la oleaginosa y oligopólica la harinera; ambas integradas verticalmente desde el punto de vista empresarial. Adicionalmente, un nivel más desagregado del trabajo realizará una exploración en profundidad de ambas industrias. Flint se apoya para este efecto en el modelo teórico creado por el profesor Michael Porter, sobre "Estrategia Competitiva", que permite identificar las fuerzas competitivas para el análisis de un sector industrial: amenazas de ingreso en el sector, intensidad de la rivalidad entre los competidores existentes, presión de productos sustitutos, poder negociador de compradores y poder negociador de los proveedores. A ellos el análisis de Flint . suma el aporte de Eduardo Bueno Campos: el Estado y los propietarios.
La desprotección del cónyuge y del tercero en la sociedad de gananciales
Authors: Almeida Briceño José
Published: June 2023

Este libro presenta un amplio panorama sobre las materias más controvertidas en la sociedad de gananciales: la disposición unilateral de los bienes sociales y la responsabilidad de estos frente a deudas privativas
Las doctrinas tradicionales frente a la contratación computarizada : análisis del funcionamiento de las doctrinas tradicionales sobre consentimiento, nulidad, anulabilidad y disentimiento en los contratos celebrados a través de medios informáticos
Authors: Castillo Freyre Mario , de Trazegnies Granda Fernando
Published: June 2023

El advenimiento de la tecnología de la información ha signado el desarrollo de la sociedad contemporánea. Hoy, en efecto, la cultura de nuestro tiempo se explica por la influencia que en ella ejerce el despliegue vertiginoso de la información. Y el Derecho no se ha mantenido ajeno a esta realidad. El presente trabajo se ubica en el horizonte generado por estas transformaciones con la mira puesta en el examen de los principios jurídicos cuestionados por el impacto delas tecnologías informáticas.
Reglas simples para un mundo complejo
Authors: Epstein Richard A.
Published: June 2023

La primera edición en inglés de Reglas simples para un mundo complejo fue publicada en 1995 por la Universidad de Harvard, y la presente constituye su primera edición en castellano. En Reglas simples para un mundo complejo, el autor critica la cada vez más agobiante y complicada regulación presente en los ordenamientos jurídicos, así como la excesiva intervención del Estado en las actividades de los particulares. En lugar de ello, Epstein, firme creyente de que los acuerdos cooperativos entre los individuos son mejores si están sujetos solo a su voluntad en lugar de al control público, propone el establecimiento de un orden jurídico basado en pocas reglas, simples, que no limiten la autonomía de los individuos. El libro, además de explicar las seis reglas básicas (reglas sobre autonomía o «propiedad sobre uno mismo», propiedad, contratación, responsabilidad civil extracontractual, contratación forzada y expropiaciones) que debe contener un sistema jurídico, analiza temas tan interesantes y polémicos como las relaciones laborales, la discriminación, la responsabilidad profesional y por productos defectuosos, y el medio ambiente, entre otros.
Integrating EMDR With Enhanced Cognitive Behavioral Therapy in the Treatment of Bulimia Nervosa: A Single Case Study
Authors: Ergüney-Okumuş F. Elif
Published: June 2023

Eating disorders (EDs) are complex and treatment-resistant problems. Despite evidence-based methods like enhanced cognitive behavioral therapy (CBT-E), the number of clients who do not respond positively to treatment is also remarkable. Eye movement desensitization and reprocessing (EMDR) therapy has been adapted for EDs. As far as it is known, no case study has been reported in which EMDR was integrated with CBT-E in the treatment of EDs. This study provides a detailed description of the treatment of a participant with bulimia nervosa (BN) who received 20 sessions of CBT-E followed by five sessions of EMDR with a focus on body image. Presenting symptoms were measured on the Eating Attitudes Test-26, Eating Disorder Examination Questionnaire, Eating Disorder Belief Questionnaire, Bulimia Nervosa Stages of Change Questionnaire, and Body Satisfaction Scale. Results showed that the client had important improvements in terms of symptoms (binge-eating, restricting, and preoccupation with weight, shape, and eating) as well as motivation, body satisfaction, and social relations. This single case study provides preliminary evidence for the possible effectiveness of CBT-E plus EMDR in the treatment of BN. It also indicates that EMDR can make unique positive contributions to treatment. In this context, the use of EMDR as an integrative method appeared to increase the effectiveness of treatment results.
“There Is No Part of My Life That Hasn’t Been Destroyed”: The Impact of Parental Alienation and Intimate Partner Violence on Fathers
Authors: Hine Benjamin A. , Bates Elizabeth A.
Published: June 2023

Previous research has demonstrated the profound negative impact of both intimate partner violence (IPV) and parental alienation (PA) on both the mental and physical health of fathers. However, considering the increasing arguments for PA to be categorized and examined as a form of IPV, there is an urgent need to explore the impact of PA as part of a broader pattern of IPV. This is a particularly relevant line of inquiry for fathers as men are largely invisibilized in research examining IPV. The present study analyzed qualitative responses to an online survey by 171 fathers who have experienced alienating behaviors within the context of IPV. Three themes were identified: impact on fathers (including health, finances, grief, identity, and relationships), perceived impact on children (including siblings and extended family, health and well-being, and loss of childhood), and impact on relationships with children (including lack of closeness, feeling responsible, and improvements over time). The impacts described by men are discussed in relation to the theoretical and practical relationship between IPV and PA, and the implications for support and help-seeking for men experiencing this form of abuse.
Una aproximación a la metáfrasis escurialense del libro primero de la Ilíada
Authors: Pérez Moro David
Published: June 2023

El estudio de las metáfrasis bizantinas de la Ilíada de Homero ha avanzado de forma demasiado paulatina en el último siglo, motivo por el cual muchas de estas reescrituras en la actualidad continúan sin ser estudiadas. El objetivo del presente artículo es realizar una primera aproximación a una de las metáfrasis bizantinas inéditas del poema homérico. Para lograr dicho objetivo, se analizará el libro primero de la metáfrasis partiendo de los manuscritos que la contienen. Además, se examinarán tanto las fuentes como la metodología de su autor y la trascendencia de esta metáfrasis comparándola con otras reescrituras del poema homérico. Este análisis permitirá concluir, en primer lugar, que la metáfrasis denominada bodleiana está formada por tres versiones diferentes; en segundo lugar, que el autor se inspiró en los escolios a la Ilíada como fuente para elaborar su obra y, por último, que esta obra se empleó en la composición de reescrituras posteriores.
“Humildad” y “orgullo” en la Homilía sobre la humildad (PG 31, 525 A-540 B) de Basilio de Cesarea (329-379)
Authors: Valdés García María Alejandra
Published: June 2023

Nuestro objetivo es abordar desde el texto original griego los términos con que Basilio de Cesarea expresa los conceptos de “humildad” y “orgullo” en su  Homilía 20 Sobre la humildad contrastando la parquedad del primero y la abundancia de sinónimos existentes para el segundo, y sus múltiples posibilidadesde traducción.
A HISTÓRIA DA MÚSICA NOS PROJETOS PEDAGÓGICOS DOS CURSOS DE LICENCIATURA EM MÚSICA DO RIO GRANDE DO SUL
Authors: Sphor Bárbara Cecília , Wolffenbüttel Cristina Rolim
Published: June 2023

Esta pesquisa investigou a presença de aspectos históricos e histórico-musicais nos currículos dos cursos de licenciatura em Música de universidades públicas do Rio Grande do Sul. O desenho metodológico incluiu a abordagem qualitativa, a pesquisa documental como método e a coleta de documentos como técnica para a coleta dos dados. Para a análise dos dados coletados utilizou-se a análise de conteúdo. Reconhecendo a variedade de possibilidades de desenvolvimento desta pesquisa e, de acordo com o método utilizado, os dados coletados na investigação foram os projetos pedagógicos dos cursos de licenciatura em Música. O referencial teórico constituiu-se de teorias do currículo e organização disciplinar (LOPES; MACEDO, 2011); a importância do conhecimento histórico para formação do indivíduo (FONTOURA, 2016); e as dimensões pedagógico-musicais e como elas estão imbricadas às diversas disciplinas, em especial à história e à musicologia (KRAEMER, 2000). Com base nos dados coletados e, à luz do referencial teórico, concluiu-se que os aspectos históricos e histórico-musicais estão presentes nos currículos dos cursos de licenciaturas em música, foco desta investigação. Além disso, observou-se que estes aspectos se apresentam nos componentes curriculares obrigatórios e eletivos/optativos, além de a forma organizacional variar, considerando-se o currículo e a instituição.
Investigation of processes in the WLTC test of a passenger car with a diesel engine
Authors: Andrych-Zalewska Monika
Published: June 2023

The tests were carried out in accordance with the WLTP (Worldwide Light Duty Test Procedure), on a passenger car with a compression ignition engine. The analysis was conducted doe the following variables: vehicle speed, exhaust emission rate and fuel consumption volumetric rate. The subject of the research are exhaust emission components that are harmful to the health of living organisms: carbon monoxide, hydrocarbons and nitrogen oxides, as well as greenhouse gases. The research results have shown a very large range of values for carbon monoxide, organic compounds and nitrogen oxides emission rate characteristics. The average distance-specific emissions values of carbon monoxide, organic compounds and nitrogen oxides were very small and were in line with the Euro 6 requirements within a large margin. Correlation studies of the measured variables were conducted – between vehicle speed and exhaust emission rate as well as volumetric fuel consumption rates, and between exhaust emission rates and volumetric fuel consumption rates. Dimensionless statistical characteristics of the measured variables were determined, such as: extreme values, range, mean value, median, standard deviation, kurtosis, skewness and coefficient of variation. The coefficient of variation analysis made it possible to assess that the most dynamic properties could be observed in organic compounds emission rate, followed by carbon monoxide and nitrogen oxides emission rates, and finally – the vehicle speed. The vehicle speed histogram was characterized by relative uniformity apart from the dominance of the idle speed. Histograms of exhaust emission rate variables were most frequently dominated by small values.
Prevalence of permanent numeric dental anomalies in panoramic radiography in an Iranian population
Authors: Shokri Abbas , Bakhshaei Anahita , Tapak Leili , Shokouhi Parisa
Published: June 2023

Aim: Dental number anomalies are a group of congenital developmental disorders divided into two groups supernumerary and missing teeth. This study was conducted to investigate the prevalence of numeric dental anomalies using panoramic images in patients referred to the Hamadan Dental Faculty. Methods: In this cross-sectional study, 2,197 panoramic radiographs of patients aged 6-49 years were evaluated. These anomalies are divided into two groups: 1) Supernumerary teeth, including Mesiodens, Distodens, and Peridens, and 2) Missing teeth, including Hypodontia, Oligodontia, and Anodontia. A Chi-square test was performed to assess the relationship between the anomalies. Data analysis was performed using SPSS 16, in which P-value < 0.05 was considered the statistical significance level. Results: Of 736 males (32.2%) and 1548 females (67.8%) in this study, 32 (4.3%) and 55 cases (3.8%) had supernumerary teeth, respectively. The prevalence of supernumerary teeth was 0.3%, 0.5%, and 0.6% in males and 0.2%, 1% and 1.2% in females for mesiodens, distodens, and peridens, respectively. Also, 243 males (10.6%) and 655 females (28.6%) had missing teeth anomalies. Hypodontia in the maxilla was the most common anomaly in both genders, while mesiodens was the least common. Conclusion: Hypodontia was the most common anomaly, followed by peridens; the least common anomaly was mesiodens. The prevalence of supernumerary teeth was greater in males, though the difference was not statistically significant. In comparison, females had a greater prevalence of missing teeth.
Mitigating the impact of skin necrosis in reconstruction after nipple-sparing mastectomy
Authors: Black Grant G. , Chen Yunchan , Wang Marcos Lu , Condez Karina , Otterburn David M.
Published: June 2023

Skin flap necrosis is a common postoperative complication after breast reconstruction, with an incidence of up to 43.4% among patients undergoing nipple-sparing mastectomy. Necrosis can adversely impact aesthetics due to the need to excise nonviable tissue, and increase the risks of infection, implant loss, nipple-areola complex sacrifice and malposition. Patient-specific factors including age, body mass index, and breast size may affect the risk of necrosis. Mastectomy and reconstruction techniques (i.e., choosing between skin- and nipple-sparing mastectomy, and between autologous and alloplastic reconstruction) may also influence necrosis rates. Intraoperative measures such as indocyanine green angiography and autologous skin banking, and the postoperative use of nitroglycerin paste for high-risk patients and warming blankets for autologous reconstruction are methods to help prevent and minimize the morbidity of skin necrosis. Herein, we share our institution’s approaches to predicting and mitigating skin necrosis, and methods of optimizing outcomes for breast reconstruction patients.
Evaluation of a global training program in One Health communication
Authors: Thomson Deborah J. , Ma Doris , Lennard Patrick R. , Ferri Maurizio
Published: June 2023

Aim: A global Train-the-Trainer Program, focused on improving the communication techniques of One Health advocates, is assessed and evaluated in this study. Methods: Between November 2020 and November 2022, a Train-the-Trainer Program engaged 1.583 trainees from 98 countries between the ages of 18 and 74. Trainees practiced public speaking by teaching a lesson about One Health in mostly underserved primary school classrooms. Two surveys of trainees (n = 222 and 203) assessed the impact of the Program’s orientation session on their confidence in science communication to a novice audience. The classroom teacher survey (n = 184 teachers, representing 4.109 students) measured the trainee’s impact at the community level during and following the lesson. Results: The Program significantly improved the trainee’s confidence in communicating science (0.1 scale points) and teaching novice audiences (0.3 scale points) about One Health. Trainees cultivated student interest in One Health [median = 9 (7.3, 10)] and 90.8% of responding classroom teachers reported a desire to continue teaching about One Health after the trainee’s lesson, 99.1% noted a post-lesson increase in student interest in science, and 97.4% recommended this lesson to their colleagues. Conclusion: This study was the first to evaluate an extensive One Health-focused communication program finding the model effective for trainees and communities alike. The trainees, through public speaking, active teaching and engaging mostly primary school students, mainstreamed One Health and inspired action in communities. The classroom teachers benefited by learning about One Health and gained a desire to share this new knowledge with others in their community.
Conceptualising Micromobility: The Multi-Dimensional and Socio-Technical Perspective
Authors: Behrendt Frauke , Heinen Eva , Brand Christian , Cairns Sally , Anable Jillian , Azzouz Labib , Glachant Clara
Published: June 2023

Micromobility has gained attention from policymakers, industry stakeholders, and academia; however, a comprehensive conceptualization of micromobility is still missing. Existing definitions are largely vehicle-centric: either listing modes or detailing vehicle characteristics. This paper addresses this gap by developing a ‘beyond vehicles’, multi-dimensional conceptualization of micromobility, accompanied by a novel socio-technical definition. Through a review of related concepts, combined with an analysis of the use and definitions of the term micromobility in publications, this study establishes a new conceptualization of micromobility. It incorporates human, social, and cultural dimensions, considers environmental, economic, infrastructure, vehicle technology, regulatory and policy aspects, and considerations for public health. Our definition of micromobility encompasses a wide range of mobility options typically used for shorter trips and manoeuvrable by an individual without motor assistance, at least for short distances. These modes are characterized by their ‘micro’ attributes, including low energy demand, environmental impact, and road space use relative to automobility. The conceptualization incorporates a range of micromobility modes, including fully human-powered (including walking), partially motor-assisted, and fully powered options. These modes typically operate at speeds not exceeding 25 to 32 kilometres per hour (or 45 km/h for faster options), weigh (typically substantially) below 350 kilograms and often yield significant (public) health benefits. Trip length is generally less than 15 kilometres, and daily distances under 80 kilometres. Importantly, our definition includes the practices, policies, cultures, and infrastructures that emerge around the use of micromobility options and shape their uptake. This proposed conceptualization significantly broadens the prevailing vehicle-focus in micromobility debates towards a socio-technical perspective. Embracing a widely accepted conceptualisation of micromobility would offer several advantages, including robust design standards, legislation, and evaluation metrics and methods. Additionally, this paper highlights the pivotal role micromobilities can play in transcending the limitations of automobility, towards more sustainable and equitable mobility futures.
In-silico Based Designing of Benzo[d]thiazol-2-amine Derivatives as Analgesic and Anti-Inflammatory Agents
Authors: Mishra Arun K. , Thajudeen Kamal Y , Salam Shahana , Singh Mhaveer , Rasool Gulam , Kumar Arvind , Singh Harpreet , Sharma Kalicharan , Mishra Amrita
Published: June 2023

The synthesis of the presented benzo[d]thiazol-2-amine derivatives was performed by condensing-(4-chlorobenzylidene) benzo[d]thiazol-2-amine with a number of substituted phenols in the presence of potassium iodide and anhydrous potassium carbonate in dry acetone. IR spectroscopy, 1HNMRspectroscopy and spectroscopy methods were used to characterize the structural properties of newly synthesized derivatives. In order to observe the attributes of drug-like candidates of these derivatives, the number of their molecular properties was estimated. Benzo[d]thiazol-2-amine derivatives were molecularly docked with selective enzymes COX-1 and COX-2. Findings suggested that Compounds G3, G4, G6, G8 and G11 possess higher binding affinity than diclofenac sodium, when docking was performed with enzyme COX-1. Compounds G1, G3, G6, G8and G10 showed lower binding affinity than Indomethacin when docking performed with enzyme COX-2.In vitro evaluation of the COX-1 and COX-2 enzyme inhibitory activities were performed for synthesized compounds. Compounds 10 and 11 exhibited significant COX-1 and COX- enzyme inhibitory action with IC50 values of 5.0 and 10 µM, respectively. Using the hot plate method and the carrageenan-induced rat paw edema model, the synthesized compounds were screened for their biological activities, including analgesic and anti-inflammatory activities.
The highest analgesic action was exhibited by derivative G11and the compound G10 showed the highest anti-inflammatory response.
Forest Wildfires in Chile: Effects on Soil Degradation and Damage Mitigation
Authors: Matus Francisco Javier , Duarte Efraín , Rojas Claudia , Smith-Ramírez Cecilia , Rubilar Rafael A , Merino Carolina , Aburto Felipe , Jofre Ignacio , Stehr Alejandra , Nájera Francisco , Dörner José , Morales Luis
Published: June 2023

The 2022-2023 Chilean summer showed increased temperatures and similar burned area, compared to the 2016-2017 season, where more than 500,000 hectares were compromised, mainly in the rural areas. After a brief review, it is revealed that the effects of forest fires on soil and hydrological properties are barely debated in Chile. Here, we showed a climatological analysis where temperature records in the 2016-2017 season were unusual, as well as another unexpected increase in the summer of 2022-2023, resulting in high-severity fires known as ‘mega-fires’ or “storm-fires”. Mega-fires affect forest plantations and native forests mainly from 33º S (Maule Region) to 39º S (Los Ríos Region) and they are expected to become frequent due to climate change, moving from the north to the south. We present an overview of the influence of wildfires on soil components in the most affected areas (inland, Coastal, and Andes ranges), their hydrological impacts, and potential erosion risk due to high winter precipitation. We propose several management practices that could help to prevent or mitigate these events, including pre-and post-fire interventions, such as afforestation and seeding, selective logging, mulching, erosion barriers, soil preparation, and dam monitoring. We argue that any effective plan in fire-prone and affected areas should include a combination of actions taken at the hillslope scale at integral ecosystem management, whose effectiveness should be monitored and verified regionally at the watershed scale.
Computation of Matrix Determinants by Cross-Multiplication: A Rethinking of Dodgson’s Condensation and Reduction by Elementary Row Operations Methods
Authors: Protacio Judel Villas
Published: June 2023

We formulate a more straightforward, symmetry-based techniques in manually computing the determinant of any n×n matrix by revisiting Dodgson’s condensation method and strategically applying elementary row operations and the definition and properties of determinants. The result yields a more simplified mnemonical algorithm than the usual reduction by elementary row operations and co-factor expansion and with minimal terminal divisions performed compared to Dodgson’s internal divisions.
Piceatannol as an Antiviral Inhibitor of Prv Infection in Vitro and in Vivo
Authors: Wang Zhi ying , Cai Xiaojing , Ren Zhiyuan , Shao Yi , Xu Yongkang , Fu Lian , Zhu Yan
Published: June 2023

Piceatannol is a naturally occurring polyphenolic compound that is widely found in grapes, blueberries, mushrooms, passion fruit and other edible fruits and vegetables. It has a variety of biological activities and pharmacological effects, including anti-inflammatory, antioxidation, antiaging, antiviral, antitumor, anticancer, antiatherosclerosis, antiparasitic, immunoregulatory, and cardiovascular protection effects. The aim of this study was to investigate the antiherpesvirus effects of piceatannol. Pseudorabies virus (PRV) belongs to the family Herpesviridae. PRV has a wide host range and can cause cytopathic effects (CPEs) in PK-15 cells. Therefore, PRV was used as a model to study the antiherpesvirus effect of piceatannol. In this study, we evaluated the antiviral activity of piceatannol against PRV in vitro and in vivo. The results showed that piceatannol could reatrain PRV multiplication in PK-15 cells in a dose-dependent manner. The 50% inhibitory concentration (IC50) was 0.0307 mg/mL, the IC50 was 0.0307 mg/mL, and the selectivity index (SI, CC50/IC50) was 3.68. The addition of piceatannol at different stages of PRV infection inhibited the viral adsorption and intracellular replication phases of PRV. Piceatannol significantly reduced the expression levels of the IE180, EP0, UL29, UL44, US6 and UL27 genes of PRV within 48 h, significantly reduced the expression levels of the PRV gB and gD proteins, and reduced PRV-induced apoptosis. Molecular docking showed that piceatannol had good binding activity with the PRV gB and gD proteins. The results of animal experiments in vitro indicated that piceatannol could delay the onset of disease, improve the survival rate of the mice (14.3%), reduce the viral load in the brain and kidney of the mice, alleviate the pathological changes in the mouse tissues and organs, and increase the levels of TNF-α, IEN-γ and IL-4 in the serum of the mice. These data indicate that piceatannol has good anti-PRV activity in vitro and in vivo, indicating that it could be a novel antiherpesvirus infection agent in the future.
Antimicrobial Resistance and Prevalence of Methicillin-resistant Staphylococcus aureus in Bovine Mastitis Milk from Conventional and Organic Dairy Farms in South Korea
Authors: Neri Therese Ariane N. , Park Hyunjung , Kang Sujin , Baek Seung Hee , Nam Insik
Published: June 2023

Bovine mastitis (BM) has been causing great economic and financial losses in the dairy industry worldwide and one of its major pathogenic agents is S. aureus. BM treatment still relies on antibiotics. The extensive use of antimicrobials gives rise to bacterial strains such as methicillin-resistant S. aureus (MRSA) and mupirocin-resistant S. aureus (MuRSA). This study aimed to investigate and compare the prevalence of MRSA and MuRSA and antimicrobial susceptibility in S. aureus isolates from bovine mastitis milk in conventional and organic dairy farms. Milk samples were taken from mastitis-infected cattle in 6 conventional and 7 organic dairy farms from South Korea. According to the Food Codex, 163 suspected S. aureus colonies were isolated from the pooled milk samples from each farm. Further rapid coagulase test confirmed 11 out of 74 isolates from 4 conventional farms (CF1, CF2, CF3, CF4) while 17 out of 89 isolates from 3 organic farms (OF1, OF2, OF3) exhibited coagulase activity. Multiplex PCR amplification showed that the nuc gene marker for S. aureus was found in all coagulase-positive isolates from OF 1 and at least one isolate from CF1, CF2, CF3, and CF4. Conversely, only 2 isolates from CF2 contained mecA gene for MRSA while none had the mupA gene for MuRSA. Antimicrobial susceptibility testing revealed that conventional farm isolates were more resistant to antibiotics particularly, against ampicillin and tetracycline, and, in turn, could imply a potential to develop multidrug resistance if stringent measures to control antimicrobial use in dairy farms is not implemented properly.
Proteome and Interactome Linked to Metabolism, Genetic Information Processing, and Abiotic Stress in Gametophytes of Two Woodferns
Authors: Ojosnegros Sara , Alvarez José Manuel , Grossmann Jonas , Gagliardini Valeria , Quintanilla Luis G. , Grossniklaus Ueli , Fernández Helena
Published: June 2023

Ferns and lycophytes, now known as monilophytes, have received scant molecular attention in comparison to angiosperms. The advent of high-throughput technologies allowed an advance towards a greater knowledge of their elusive genomes. In this work, proteomic analyses of heart-shaped gametophytes of two ferns were performed: the apomictic species Dryopteris affinis ssp. affinis and its sexual relative Dryopteris oreades. In total, a set of 218 proteins shared by these two gametophytes were analyzed using the STRING database, and the proteome associated with metabolism, genetic information processing, and responses to abiotic stress is discussed. Specifi-cally, we report proteins involved in the metabolism of carbohydrates, lipids, and nucleotides, the biosynthesis of amino acids, and secondary compounds, energy, oxido-reduction, transcrip-tion, translation, protein folding, sorting and degradation, and responses to abiotic stress. Look-ing at the interactome of this set of proteins, it represents a total network composed of 218 nodes and 1,792 interactions, obtained mostly from databases and textmining. The interactions among the identified proteins of the ferns D. affinis and D. oreades, together with the description of their biological functions, might contribute to a better understanding of the function and develop-ment of ferns as well as to fill knowledge gaps in plant evolution.
Metabolome Mining of Curcuma longa L. Using HPLC-MS/MS and Molecular Networking
Authors: Budhathoki Rabin , Timilsina Arjun Prasad , Regmi Bishnu P. , Sharma Khaga Raj , Aryal Niraj , Parajuli Niranjan
Published: June 2023

Turmeric, Curcuma longa L., is a type of medicinal plant characterized by its perennial nature and rhizomatous growth. It is a member of the Zingiberaceae family and is distributed across the world’s tropical and subtropical climates, especially in South Asia. Its rhizomes are highly valued for food supplements, spices, flavoring agents, and yellow dye in South Asia since ancient times. It exhibits a diverse array of therapeutic qualities that encompass its ability to combat diabetes, reduce inflammation, act as an antioxidant, exhibit anticancer properties, and promote anti-aging effects. In this study, organic extracts of C. longa rhizomes were subjected to HPLC separation followed by mass spectrometry analysis. The Global Natural Product Social Molecular Networking (GNPS) approach was utilized for the first time in this ethnobotanically important species to conduct an in-depth analysis of its metabolomes based on their fragments. A total of 30 metabolites including 16 diarylheptanoids, 1 diarylpentanoid, 3 bisabolocurcumin ethers, 4 sesquiterpenoids, 4 cinnamic acid derivatives, and 2 fatty acid derivatives were identified. Among 16 diarylheptanoids identified in this study, five of them are reported for the first time in this species.