bluuebunny/crossref_metadata_2025 huggingface dataset:
Sequência didática interdisciplinar: Sherlock Holmes no ensino de química
Authors: Melato de Neri de Sousa Breno , Gaiotto Paulo Alexandre , Terhaag Marcela Moreira , Calaça da Trindade Giselle Nathaly , Martins Darliane Aparecida
Published: October 2024

O presente trabalho trata da aplicação de uma sequência didática interdisciplinar com o tema de química forense. O objetivo foi trabalhar, no primeiro ano do curso Técnico em Química integrado ao Ensino Médio, diferentes metodologias, como práticas experimentais, leitura de textos, para a assimilação do conteúdo de vidrarias de laboratório e confecção de relatórios de forma interdisciplinar, utilizando partes da obra Sherlock Holmes. As histórias lidas auxiliaram os estudantes a interpretar situações que envolvem química. Foi simulado um roubo no laboratório de química e os alunos identificaram o criminoso dentre quatro suspeitos por meio da técnica de revelação de digital, utilizando vapor do iodo, e de comparação entre sequenciamento de DNA simulado do sangue encontrado na cena do crime e dos suspeitos. Constatou-se que houve boa interação dos alunos, resultando em participação ativa nas atividades experimentais e de escrita, o que levou a relatos coerentes do que foi realizado. Notou-se que eles não haviam tido contato com laboratório até então e ao fim da sequência didática, puderam assimilar tanto o nome quanto a função das principais vidrarias. Diante disso, evidenciou-se que a partir de diferentes metodologias e interação entre alunos e professores a assimilação de conteúdo, aconteceu de maneira significativa.
Diretrizes para ampliar a divulgação científica de grupos de pesquisa em plataformas de mídia social: relevância, análise na UFOP e principais ferramentas
Authors: Rezende Matheus Lucas , Freitas Mendes Vítor , Carvalho Aldo Ribeiro de , Mendes Júlia Castro
Published: October 2024

As plataformas de mídia social têm se mostrado ambientes excepcionalmente favoráveis para a divulgação científica, dada sua ampla cobertura e poder de engajamento. Assim, este estudo visa encorajar e facilitar o uso das redes sociais por grupos de pesquisa na disseminação da ciência. Para isso, realizamos um diagnóstico do cenário atual da Universidade Federal de Ouro Preto e introduzimos conceitos e ferramentas relacionados às melhores práticas para transmissão de informações científicas através das principais plataformas de mídia social da atualidade, Facebook, Instagram, Twitter, LinkedIn e YouTube. Observamos grupos interessados em usar as redes sociais, mas lhes faltam ferramentas e recursos necessários. Parte significativa desses grupos (63%) não tem plataformas de mídia social para esse fim. Além disso, notamos que a maioria dos pesquisadores com redes sociais não utiliza alguns dos principais mecanismos de engajamento, como hashtags, call to action e frequência de postagem constante. Portanto, este estudo elucida as principais funções das redes sociais e facilita o uso dessas ferramentas por meio de uma revisão bibliográfica de pesquisas recentes. Buscamos incentivar a divulgação científica feita por pesquisadores em redes sociais, a fim de aumentar a visibilidade dos grupos de pesquisa, o reconhecimento da instituição e o impacto de seus projetos.
Preparándose para la guerra: la Armada Argentina y sus hipótesis de conflicto en Sudamérica durante la década de 1920
Authors: Desiderato Agustín
Published: October 2024

As a result of the impacts and effects of the First World War, during the 1920s, the Argentine Navy was undergoing a pronounced process of material obsolescence. To reverse this situation, its authorities developed a series of studies, outlining possible acquisition and modernization programs that would respond, among other issues, to the existing conflict scenarios in the region. This article will analyze Comparative Study on South American Naval Power, a little-explored source found in the library of the National Naval Museum, which includes a set of memoirs and reports prepared by the General Staff of the Navy in 1923. It details the plans and deployments envisioned by the Navy in the event of war with Brazil, Chile, and Uruguay -nations perceived as rivals at the timealong with the various courses of action and the equipment that would need to be acquired to ensure the success of the operations.
Geopolitical Implications of Transboundary Rivers in South Asia Region
Authors: Yadav Kumari Nishu
Published: October 2024

The Contemporary era is Characterised by intensified competition for water resources among the nations,in the twenty –first century’s global order, hydro-politics emerged as a crucial enemy that significantlyimpacted the strategic landscape and national security has become closely linked to several geopolitics’factors. South Asia is grappling with numerous internal issues, the three major river systems the Ganges,Indus, and Brahmaputra River basins serves as the geopolitical tensions in the region. The researchexamines the historical context and ongoing conflicts between India, Pakistan, China, and Bangladesh overthese critical water resources. It investigates the causes of disputes, such as dam development and water-sharing agreements, as well as their implications for regional stability. The analysis emphasizes the criticalneed for collaborative management and long-term solutions to solve water security and promote regionalharmony.
India-China Geopolitical Tensions: Strategic and NationalSecurity Implications with respect to Maldives
Authors: Umesh M. Uttara , Sreenivas Aishwarya
Published: October 2024

The geopolitical landscape of the Indian Ocean is undergoing significant shifts, with thechanging political dynamics in the Maldives, the evolving India-China relationship, and India'sstrategic moves in the Lakshadweep archipelago. This paper examines the intricate interplaybetween domestic politics, regional alliances, and strategic concerns in the Indian Ocean,focusing on the implications for India's national security. The Lakshadweep-Maldives-Chagosarchipelago has historically been strategically important to India, and recent developments,such as the establishment of India’s second naval facility in the Lakshadweep and the politicalshift in the Maldives, have brought this region into the spotlight. The changing India-Chinarelationship, fuelled by China's growing influence in the Maldives and India's historical tieswith the previous Maldivian administration, has raised concerns about the potential creation ofa power vacuum in the Indian Ocean. The Maldivian President's call for the withdrawal ofIndian troops from the country could potentially favour China's influence and jeopardize vitalsea routes, increasing the risks of instability, piracy, terrorism, and other criminal activities.India's proactive diplomacy under its "Neighbourhood First Policy" aims to sustain its imageas a great power while countering China's rise in the region. This research explores therelationship between China and the Maldives, its implications for India, and the patterns ofinvestment by both India and China in the Maldives. The broader implications of the India-China geopolitical conflict on India's national security in international waters are also examined.
GDF2 and BMP10 coordinate liver cellular crosstalk to maintain liver health
Authors: Zhao Dianyuan , Huang Ziwei , Li Xiaoyu , Wang Huan , Hou Qingwei , Wang Yuyao , Yan Fang , Yang Wenting , Liu Di , Yi Shaoqiong , Han Chunguang , Hao Yanan , Tang Li
Published: October 2024

The liver is the largest solid organ in the body and is primarily composed of hepatocytes (HCs), endothelial cells (ECs), Kupffer cells (KCs), and hepatic stellate cells (HSCs), which spatially interact and cooperate with each other to maintain liver homeostasis. However, the complexity and molecular mechanisms underlying the crosstalk between these different cell types remain to be revealed. Here, we generated mice with conditional deletion of Gdf2 (also known as Bmp9) and Bmp10 in different liver cell types and demonstrated that HSCs were the major source of GDF2 and BMP10 in the liver. Using transgenic ALK1 (receptor for GDF2 and BMP10) reporter mice, we found that ALK1 is expressed on KCs and ECs other than HCs and HSCs, and GDF2 and BMP10 secreted by HSCs promote the differentiation of KCs and ECs and maintain their identity. Pdgfb expression was significantly upregulated in KCs and ECs after Gdf2 and Bmp10 deletion, ultimately leading to HSCs activation and liver fibrosis. ECs express several angiocrine factors, such as BMP2, BMP6, Wnt2, and Rspo3, to regulate HC iron metabolism and metabolic zonation. We found that these angiocrine factors were significantly decreased in ECs from Gdf2/Bmp10HSC-KO mice, which further resulted in liver iron overload and disruption of HC zonation. In summary, we demonstrated that HSCs play a central role in mediating liver cell-cell crosstalk via the production of GDF2 and BMP10, highlighting the important role of intercellular interaction in organ development and homeostasis.
Kapittel 4: Tverrfagleg havari – men samfunnsplanlegging overlevde dei turbulente 1980-åra
Authors: Aarsæther Nils
Published: October 2024

1980-talet skulle bli eit problemfylt tiår for den tverrfaglege utdanninga i samfunnsplanlegging og lokalsamfunnsforsking ved Universitetet i Tromsø. Sjølv om utdanninga gjennom 1970-talet hadde fått studieløpet og forholdet til praksisfeltet på plass, skulle studieretninga virke i eit akademisk miljø som ved inngangen til 1980-talet opplevde stagnasjon i stillingstildelingar og studenttal.
FERDCNN: an efficient method for facial expression recognition through deep convolutional neural networks
Authors: Rashad Metwally , Alebiary Doaa , Aldawsari Mohammed , Elsawy Ahmed , H. AbuEl-Atta Ahmed
Published: October 2024

Facial expression recognition (FER) has caught the research community’s attention recently because it can affect many real-life applications. Multiple studies have focused on automatic FER, most of which use a machine learning methodology, FER has continued to be a difficult and exciting issue in computer vision. Deep learning has recently drawn increased attention as a solution to several practical issues, including facial expression recognition. This article introduces an efficient method for FER (FERDCNN) verified on five different pre-trained deep CNN (DCNN) models (AlexNet, GoogleNet, ResNet-18, ResNet-50, and ResNet-101). In the proposed method, firstly the input image has been pre-processed using face detection, resizing, gamma correction, and histogram equalization techniques. Secondly, the images go through DCNN to extract deep features. Finally, support vector machine (SVM) and transfer learning are used to classify generated features. Recent methods have been employed to evaluate and contrast the performance of the proposed approach on two publicly standard databases namely, CK+ and JAFFE on the seven classes of fundamental emotions, including anger, disgust, fear, happiness, sadness, and surprise beside neutrality for CK+ and contempt for JAFFE. The suggested method tested Four different traditional supervised classifiers with deep features, Experimental found that AlexNet excels as a feature extractor, while SVM demonstrates superiority as a classifier because of this combination achieving the highest accuracy rates of 99.0% and 95.16% for the CK+ database and the JAFFE datasets, respectively.
Human–robot interaction: predicting research agenda by long short-term memory
Authors: Borregan-Alvarado Jon , Alvarez-Meaza Izaskun , Cilleruelo-Carrasco Ernesto , Rio-Belver Rosa Maria
Published: October 2024

The article addresses the identification and prediction of research topics in human–robot interaction (HRI), fundamental in Industry 4.0 (I4.0) and future Industry 5.0 (I5.0). In the absence of research agendas in the scientific literature, the study proposes a multilayered model to create a precise agenda to guide the scientific community in new developments in collaborative robotics and HRI technologies. The methodology is divided into four stages, which make up the three layers of the model. In the first two stages, scientific articles on HRI for the period 2020–2021 were collected and analyzed using data mining techniques together with VantagePoint and Gephi software to identify keywords and their relationships. These initial stages form layer 1 of the model, where the main scientific themes are recognized. In the third stage, article titles and abstracts are cleaned and processed using natural language processing (NLP) techniques, generating word embeddings models that highlight relevant HRI-related terms, forming layer 2. The fourth and final stage uses Recurrent Neural Networks (RNN) with long short-term memory (LSTM) architecture to predict future topics, consolidating the previously identified terms and forming layer 3 of the model. The results show that in layer 1 HRI has intensive application in various sectors through advanced computational algorithms, with trust as a key feature. In layer 2, terms such as vision, sensors, communication, collaboration and anthropomorphic aspects are fundamental, while layer 3 anticipates future topics such as design, performance, method and controllers, essential to improve robot interaction. The study concludes that the methodology is effective in defining a robust and relevant research agenda. By identifying future trends and needs, this work fills a gap in the scientific literature, providing a valuable tool for the research community in the field of HRI.
Automated urban landscape design: an AI-driven model for emotion-based layout generation and appraisal
Authors: Tang Xiaohu , Chung Won-jun
Published: October 2024

The evolution of a city is significantly shaped by the design of its urban landscape. The advancement of artificial intelligence has substantially increased convenience for individuals. This research proposes an urban landscape layout model powered by artificial intelligence that automatically generates urban landscape design based on deep learning (URDDL) with two dimensions: emotional tendency and urban landscape appraisal. The input image represents land use and surrounding road conditions, while the output image depicts the selection of the main entrance and the internal spatial function layout. The Pix2Pix model is trained to learn the internal function layout based on varying land use and road conditions. Additionally, a domain-specific dictionary is constructed using an existing semantic resource vocabulary, where positive and negative sentiment words are compared with their corresponding sentiment values, focusing on categories such as Stimulate, Sense, and Action. Experimental results indicate that the absolute average error of the URDDL model is 91.31%, with a maximum error of 96.87%. The degree of fit is highly appropriate for evaluating the emotional prediction of urban landscapes. The findings demonstrate that the URDDL model outperforms traditional design methods regarding generated results, suggesting its potential for future applications in automated landscape design.
The regulation role of calcium channels in mammalian sperm function: a narrative review with a focus on humans and mice
Authors: Yang Yebin , Yang Liu , Han Xiaoqun , Wu Kuaiying , Mei Guangquan , Wu Baojian , Cheng Yimin
Published: October 2024

Mammalian sperm are characterized as specialized cells, as their transcriptional and translational processes are largely inactive. Emerging researches indicate that Ca2+ serves as a crucial second messenger in the modulation of various sperm physiological processes, such as capacitation, hyperactivation, and the acrosome reaction. Specifically, sperm-specific calcium channels, including CatSper, voltage-gated calcium channels (VGCCs), store-operated calcium channels (SOCCs), and cyclic nucleotide-gated (CNG) channels, are implicated in the regulation of calcium signaling in mammalian sperm. Calcium stores located in the sperm acrosomes, along with the IP3 receptors in the neck of the redundant nuclear envelope and the mitochondria in the tail, play significant roles in modulating intracellular Ca2+ levels in sperm. However, the functions and mechanisms of these calcium channels in modulating mammalian sperm physiological functions have not yet been well elucidated. Therefore, by focusing on humans and mice, this study aims to provide a comprehensive review of the current advancements in research regarding the roles of calcium signaling and associated calcium channels in regulating sperm function. This endeavor seeks to enhance the understanding of calcium signaling in sperm regulation and to facilitate the development of drugs for the treatment of infertility or as non-hormonal male contraceptives.
Effect of Different Chemical Pretreatments and Packaging Systems on Quality Characteristics of Fresh-Cut Pomegranate Arils (Punica granatum, L.)
Authors: R. Amrutha , Kumar Athulya S. , C. Mini
Published: October 2024

Aims: Pomegranate (Punica granatum) is considered as challenging to consume due to its hard structure, hence used for fresh-cut production. Extending the shelf life of fresh-cut pomegranate arils would improve their marketability, transport efficiency, and reduce post-harvest losses.
Study Design: Completely Randomized Design by using GRAPES (General R based Analysis Platform Empowered by Statistics).
Place and Duration of Study: College of Agriculture, Kerala Agricultural University, February 2022-July 2024.
Methodology: Pomegranate arils were extracted and treated with different pre-treatment solutions viz., 0.5% ascorbic acid, 0.5% citric acid, 1% calcium chloride and 1% calcium ascorbate for 4 minutes. The best pre-treatment solution was selected and arils were packaged in different packaging systems viz., shrink wrapping in 15µ polyolefin film, vacuum packaging in laminated pouches, MAP with N2 flushing in laminated pouches, aluminium tray wrapped with cling film and stored under two different storage conditions, after treating with 1% calcium ascorbate.
Results: 1% calcium ascorbate was selected as the best pre-treatment solution and pre-treated arils kept in MAP with N2 flushing in laminated pouches stored under low temperature condition was found to be the best packaging and storage system. 1% calcium ascorbate treated arils in MAP with N2 flushing in laminated pouches stored under low temperature condition (10±5oC) had a shelf life of 6 days with superior physiological (PLW, percent leakage), chemical (acidity, vitamin C, phenol) and sensory characters (color, flavour, texture, appearance, taste and overall acceptability) as compared to control (2.00 days). Maximum vitamin C content of 23.02 mg 100g-1 and least phenol content of 214.16 mg 100g-1 were recorded on 6th day of storage.
Conclusion: Pomegranate arils pre-treated with 1% calcium ascorbate for 4 minutes, kept in MAP with N2 flushing in laminated pouches stored under low temperature condition (10±5oC) can be considered as a protocol for shelf life extension of pomegranate arils.
Evaluation of Field Performance of Groundnut Varieties through Different Vigour Tests
Authors: Chandanasree S. , Reddy B. Rupesh Kumar , Vasundhara S. , Kumar A. R. Nirmal
Published: October 2024

A field experiment was carried out to evaluate the field performance of groundnut varieties through different vigour tests during Rabi, 2023-24 at S.V. Agricultural College, Tirupati, Acharya N.G. Ranga Agricultural University, Andhra Pradesh. The experimental material consisted of 10 groundnut varieties Narayani, Dharani, Dheeraj, TCGS-1694, Nithya Haritha, Kadiri-9, Kadiri-6, Kadiri Amaravathi, Kadiri-1812 and TAG-24 collected from different sources. In the preliminary experiment seed multiplication was done and the multiplied seed was used for conducting six vigour tests namely Germination test, speed of germination test, Seedling vigour index-Ⅰ, Seedling vigour index-Ⅱ, Accelerated ageing test, Electrical conductivity test in the laboratory using Completely Randomised Design with four replications. The multiplied seed was used for evaluating field performance using Randomised block design with three replications. Significant differences were found among the varieties based on vigour levels. Results with respect to field experiment showed that growth parameters i.e. field emergence percentage, days to 50 % flowering, days to maturity, number of branches per plant, number of pods per plant, pod yield per plant, kernel yield per plant, pod yield per plot, plant height, shelling percentage, 100 seed weight and harvest index varied significantly among different varieties based on different vigour levels. Varieties with higher vigour had shown higher field emergence percentage. Among the ten varieties Kadiri-6 had shown highest field emergence percentage. Significant correlation was observed among laboratory and field experiments. Vigorous varieties were able to perform better in terms of some of the field parameters and among all the vigour tests performed speed of germination test had high correlation with field emergence.
The Impact of Next-generation Sequencing on Biotechnology: A Review of Current Applications
Authors: Singh Lukram Sushil , Iqbal Gowhar , Singh Arya , Limbola Maharshi , Kumar Ad Viral
Published: October 2024

Since sequencing was developed by Sanger and Gilbert in 1977, various sequencing methods have been introduced in biotechnology to sequence DNA. Next-generation sequencing is a novel high-tech method where the sequencing of thousands of DNA molecules can be done in parallel to generate enormous amounts of genetic data within one experiment. This novel generation of sequencing superseded conventional techniques like Sanger sequencing with parallelization to achieve rapid genome sequencing at minimum costs. In this chapter, we highlighted various applications of using NGS in different fields, such as genomic research, clinical diagnostics, metagenomics, water quality assessment, and food authenticity. Besides, NGS could identify genetic variations, diagnose diseases, and assess food quality with high accuracy, rapidity, and specificity.
Characterization of X-ray Beams: Determination of K\(_{a,e}\) for Comparison with DRLs
Authors: Claus Thiago Victorino , Cassol Luísa Vargas , Favarin Nataly Nogueira , Nogueira Laura Pizarro Trojahn , Gomes Tobias Soares , Schwarz Stefanie Camile , Torres Herculis Rolins , Baumhardt Tadeu
Published: October 2024

Aims: The aim of this experimental study was to quantify the entrance surface air kerma (Ka,e) of X-ray beams in radiographic examinations, and the obtained values were compared with national and international Diagnostic Reference Levels (DRLs).
Place and Duration of Study: Sample: Department of Medical Physics and Radiology, Franciscan University (UFN), between June 2023 and August 2024.
Methodology: Initially, the main quality control (QC) tests were applied to characterize the radiographic equipment. During the evaluation of the X-ray beam, a dosimetric set was used, and for the same QC geometry, Air Kerma Rate (KAIR) measurements were obtained to determine the output of the X-ray tube. Under the same conditions, a phantom without water and the same filled with water were used to determine the backscatter factor (BSF), which was then used to estimate the Ka,e for the main radiographic examinations.
Results: The results of this study are consistent with other studies and identified the region/anatomy with the highest radiation exposure, highlighting the importance of its optimization and verifying that continued professional training should be integrated into best practices to ensure greater safety in procedures. The results obtained evidence the necessity for adjustments in image acquisition protocols, as the Ka,e values found in this study, although within the limits established by the national DRLs, exceed the reference values of countries such as the United Kingdom and Japan in the areas of the skull, abdomen, and lumbar spine. This discrepancy highlights the importance of the periodic review and update of DRLs, in accordance with international recommendations and the technological evolution of equipment. Dose optimization is an ongoing process that involves the evaluation of image quality, the appropriate selection of technical parameters, and the implementation of specific dose protocols. The continuous training of radiology professionals is essential to ensure the correct application of imaging techniques and the minimization of patient exposure to ionizing radiation.
Conclusion: This study shows the importance of evaluating radiation dose in diagnostic imaging and the need for a multidisciplinary approach to dose optimization. Implementing quality assurance programs, updating DRLs, and providing ongoing training for professionals are essential to ensure patient safety and high-quality diagnostic imaging. The methodology adopted in this study can contribute to the ongoing education of radiology professionals, promoting the correct application of imaging techniques and reducing patient exposure to ionizing radiation.
Exploring Women Journey And Factors That Act As Glass Ceiling On Women In Getting Into Senior Management: A Literature Review
Authors: Gqozo Sivuyile , Jowah Larry
Published: October 2024

The literature review indicates that the progression of women in many fields in getting into senior management has been growing very slow. Men are still dominant in numbers when it comes to such positions, for example in the construction industry, men are still dominant in construction industry due to the fact that the working conditions of the construction environment(s) are dangerous to conduct work on and the culture of hard labor altogether with long working hours deprive women an opportunity to flourish in such environments. Therefore, there is a need to interpolate such industries into novel models and transform them into advanced state for all. Subsequently, the literature postulates that there is a need for more women to study Science, Technology, Engineering and Mathematics (STEM) fields further to be able serve in senior management positions. However, many organizations need to have women empowerment programs for those who exhibit the attributes to serve in senior management/leadership positions with the inclusion of capable women. Senior women need to mentor and train junior women within permissible structures of organizations. The literature suggests that the gap between the two genders when it comes to senior management is great apart even though women are perceived to have skills to serve in those positions. Thus, there is a need for more studies focusing on how to minimize this gender disparity as most of the studies are centric in the disparity of the two genders rather than establishing the cause and proposing solutions. Therefore, the research proposes that a new model for numerous industries ought to be generated in order to exterminate this exacerbating effect.
Effect Of Funding Structure And Liquidity On The Financial Performance Of The Sugar Industry In Kenya
Authors: Oando Odoyo Samson , Ombok Dr Benjamin O. , Ndichu Dr Peter K.
Published: October 2024

The main aim of this study was to determine the effect of funding structure on the financial performance of the sugar industry in Kenya. The relationship between funding structure and financial performance is crucial within Kenya's sugar industry, as it directly impacts resource allocation, expense management, and overall profitability. Inadequate financial management can result in liquidity challenges, affecting the sector's competitiveness and sustainability. Conversely, a well-balanced funding structure, incorporating both debt and equity, has the potential to strengthen financial stability. Stockholder, Trade-offs, and Pecking order guided the study. The study employed a correlational research design. The study's target population consisted of 16 sugar companies operational in Kenya. Purposive sampling was used to select 9 sugar companies. A total of 324 secondary data points from 2014 to 2022 were collected, including the cost of equity, debt, retained earnings, and economic value added, derived from financial statements and cash flows. The results showed a significant positive relationship between funding structure and Economic value added (coeff=0.863126, p=0.000<0.005). This reveals that Companies that maintain an appropriate funding structure are more likely to achieve higher Economic Value Added (EVA) over the long run. Given the positive long-term correlation between funding structure and EVA, it can be inferred that Kenyan sugar companies should prioritize maintaining a balanced funding structure to improve financial performance. The study concludes that funding structure has a significant relationship with economic value added
Plano De Negócios E Suas Contribuições Para Micro E Pequenos Empreendedores
Authors: Fonseca Marcello Pires , Santos Ansselmo Ferreira Dos , Santos Ellen Sandra Eduarda , Júnior Gilberto Claudino da silva , Rodrigues Agustin Pérez
Published: October 2024

A pesquisa aborda a importância do plano de negócios como ferramenta essencial para micro e pequenos empreendedores, que enfrentam desafios significativos na gestão de seus negócios. Utilizando uma metodologia de pesquisa bibliográfica, foram analisados diversos estudos e publicações em plataformas renomadas para contextualizar a relevância do planejamento estratégico. Os resultados indicam que um plano de negócios bem estruturado não só orienta a gestão e minimiza riscos, mas também educa os empreendedores sobre finanças e marketing, facilitando a captação de recursos. A análise revela que a flexibilidade e a revisão constante do plano são cruciais em um ambiente de negócios dinâmico, permitindo que os empreendedores se adaptem às mudanças e aproveitem oportunidades. Conclui-se que a elaboração de um plano de negócios é indispensável para o crescimento e a sustentabilidade das micro e pequenas empresas, contribuindo para a geração de empregos e o fortalecimento da economia local em todos os segmentos, como alimentício, saúde, educação, entre outros
A Inteligência Nas Operações De Paz De Caráter Naval: O Caso Do Líbano E Suas Lições Para A Inteligência Marítima
Authors: Nunes Prof. Me. Carlos Eduardo Vieira
Published: October 2024

Este artigo tem como objetivo apresentar uma abordagem sobre a experiência brasileira na Atividade de Inteligência (AI) da Força-Tarefa Marítima (FTM) da United Nations Interim Force in Lebanon (UNIFIL), voltada à aplicação das lições que se mostraram válidas, nessa relevante missão, à segurança marítima no Atlântico Sul, mormente à proteção do ambiente marítimo da Amazônia Azul. Como principais resultados, foram apresentados aspectos doutrinários e históricos de uma operação de paz de caráter naval, sua importância na atualidade e o papel da Inteligência em operações dessa natureza; foi abordada a AI desenvolvida na FTM, com suas especificidades, identificando-se desafios e oportunidades de melhoria, sendo analisadas a validade das lições aprendidas e a relevância de sua aplicação na segurança marítima da Amazônia Azul; e foi verificada a possibilidade de aprimoramento no processo de produção de conhecimento em apoio à tomada de decisão, na área da segurança marítima, aliando a utilização racional de novas tecnologias ao valioso trabalho humano, constatando-se a importância do incremento da AI marítima, visando à segurança e defesa da Amazônia Azul.
Microbiologia E Imunologia Médica: Desenvolvimento E Eficácia De Vacinas De Mrna Contra Variantes Emergentes Do Sars-Cov-2
Authors: Albuquerque Raquel Angélica Andrade Corrêa De , Lopes Euller Fernandes , Ramos Magno Oliveira , Lima Odaize Do Socorro Ferreira Cavalcante , Lima Agnaldo Braga
Published: October 2024

A pandemia de COVID-19 impôs à comunidade científica um desafio sem precedentes na busca por vacinas eficazes para combater o vírus SARS-CoV-2 e suas variantes emergentes. Nesse contexto, a tecnologia de mRNA surgiu como uma ferramenta inovadora e promissora, oferecendo uma nova abordagem para o desenvolvimento rápido de vacinas seguras e eficazes. Este artigo analisa o desenvolvimento de vacinas baseadas em mRNA, com foco em sua eficácia contra variantes emergentes do SARS-CoV-2. O uso dessa tecnologia permitiu uma resposta rápida à pandemia, proporcionando um alto grau de proteção em curto período. No entanto, o surgimento de novas variantes do vírus, como a Delta e a Ômicron, desafiou a eficácia dessas vacinas, exigindo adaptações contínuas nas formulações e estratégias de vacinação. Este estudo revisa os mecanismos de ação das vacinas de mRNA, o desenvolvimento de novos imunógenos específicos para variantes emergentes, e as barreiras logísticas e imunológicas associadas à administração dessas vacinas em larga escala. Além disso, são discutidas as perspectivas futuras para o uso de vacinas de mRNA em outras doenças infecciosas e suas implicações na imunologia médica. A análise inclui dados recentes sobre a eficácia das vacinas em diferentes faixas etárias e populações vulneráveis, além de explorar os desafios relacionados à produção, distribuição e hesitação vacinal
The Development Of Learner’s Self-Concept As A Function Of Education Quality In Secondary Schools In The Drc
Authors: Pendeza Vira Banzwa
Published: October 2024

Many schools in the Democratic Republic of Congo face the challenge in fostering educational quality due to learner’s negative self-concept. The use of traditional teaching methods and destructive feedback provided by most of teachers to learners greatly reduces learners’ self-concept in secondary schools, leading to failure and school dropout. However, scientific discourses in education reveals that learner’s self-concept is a key fact resulting to the learner’s motivation to learn. Learner’s self-concept is relevant at secondary school level in enhancing education quality, especially when it leads learner’s better outcomes. The present article reflects the role of the learner’s self-concept and some strategies to develop it at secondary school level for educational quality attainment in DRC
U.S.-China Trade War: Analysis Of The Semiconductor Industry
Authors: . .
Published: October 2024

This research paper analyses the causes and outcomes of the U.S.-China trade conflict through the lens of the semiconductor industry. It explores strategic measures the U.S. took to curb China’s technological progress. Furthermore, the paper looks at China’s countermeasures to mitigate the repercussions of U.S. policies. This research paper is a literature review of various research papers to unveil the causes and effects of the trade war, in the semiconductor industry. Some of the leading causes include intellectual property disputes(Huawei and ZTE) and trade relations, the outcomes of the trade war are more directed toward economic competition and global impact. The paper proposes potential policies to mitigate the damages caused by the trade war and recommends policies to create a robust economic environment. The paper explores policies that could enhance diplomatic relations and minimize trade wars. Methodology The research methodology used in this paper is a Literature review. The five main papers reviewed are... 1. “What the Huawei Case Can Teach Us about the U.S.-ChinaPower Game” by Lu Chuanying and Nicolas Huppenbauer. 2. “The U.S.-China Trade War: Is Malaysia benefiting from "Diversions" in US import demand?” by Calvin Cheng, Firdaos Rosli, and Dwintha Maya Kartika. 3. “Economic Security: Uncertainty Rises as U.S.-China Strategic Competition Deepens” by Yeon Wonho. 4. “U.S.-China Bilateral Economic Relations” by Amy P. Celico and Song Guoyou. 5. “The India-China-U.S. Triangle” by Vijay Gokhale. These research papers are analyzed to highlight some of the chief factors in the semiconductor industry that led to the trade war, as well as investigate papers to comprehend the outcomes of the trade war on the semiconductor industry
A Importância Da Gestão Educacional E Das Políticas Públicas Para A Minimização Da Evasão Escolar
Authors: Gonçalves Gustavo Henrique , Santos Adelcio Machado Dos , Oliveira Vladimir Bezerra De , Ribeiro Claudiane , Magnago Walaci
Published: October 2024

Esta pesquisa sobre a evasão escolar investiga como a gestão educacional e as políticas públicas podem mitigar esse fenômeno crítico que afeta o desenvolvimento social e econômico. Utilizando uma metodologia de pesquisa bibliográfica, foram analisados dados e estratégias de diferentes contextos, evidenciando a importância de uma gestão eficaz e de políticas bem estruturadas para criar ambientes escolares inclusivos. Os resultados mostram que uma articulação entre gestão e políticas é vital para o sucesso de programas de apoio e capacitação, e que a participação comunitária é essencial. A conclusão enfatiza que a luta contra a evasão não se resume a manter alunos nas salas de aula, mas a promover uma educação de qualidade que transforme vidas, requerendo a colaboração de todos os envolvidos no processo educativo
Capacitação De Servidores Públicos: O Processo Adotado Em Um Instituto Federal De Educação
Authors: Viana Mayuma Martins Santana , Costa Débora Vargas Ferreira
Published: October 2024

O presente estudo tem como objetivo relatar como ocorre o processo de planejamento e execução das ações de capacitação no Instituto Federal de Educação, Ciência e Tecnologia de Rondônia à luz da Política Nacional de Desenvolvimento de Pessoas. Para tanto, foi realizada uma análise em documentos institucionais, como também entrevista semiestruturada com a Diretoria de Gestão de Pessoas da instituição em questão. Trata-se de pesquisa qualitativa, de natureza aplicada com análise de conteúdos realizada com base nos pressupostos de Bardin. Os resultados alcançados mostram que mesmo com dificuldades, o Instituto Federal de Educação, Ciência e Tecnologia de Rondônia tem ações para capacitação de servidores que possibilitam a melhoria nos índices de qualificação dos servidores. Ao final, foi possível considerar que a instituição precisa reformular sua Política de Capacitação de servidores para atender à legislação vigente, bem como às necessidades de sua realidade organizacional
The Rise Of Retail Investors In India: Trends And Challenges
Authors: Sharma Prof. Prashant
Published: October 2024

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Assédio Moral No Trabalho/Workplace Bullying: Uma Revisão De Literatura
Authors: Pegoraro Daniela , Oliveira Rayssa Cleide De , Saragozo Rosangela De Arruda , Silva José Maria Alves Da , Lopes Luis Felipe Dias
Published: October 2024

Workplace bullying, recognized as a form of violence, has significant impacts on professional relationships and employee well-being. This systematic literature review aims to explore the coping strategies used by workers facing workplace bullying, with a focus on identifying the sociodemographic factors that influence trust, stress, and anxiety in the workplace. Through a comprehensive review of articles published between 2014 and 2024, this study examines the existing research on the subject, analyzing how gender, age, and marital status affect both the experience of bullying and the coping mechanisms employed. The findings suggest that women, particularly in leadership roles, and divorced individuals are more likely to experience severe stress and anxiety due to bullying, while organizational interventions remain critical for preventing and addressing such issues. This review highlights the need for further investigation into organizational-level coping strategies and the role of modern workplace dynamics, such as remote work and digital communication, in exacerbating or mitigating workplace bullying
Rate of Mass Loss Across the Instability Threshold for Thwaites Glacier Determines Rate of Mass Loss for Entire Basin
Authors: Waibel M. S. , Hulbe C. L. , Jackson C. S. , Martin D. F.
Published: January 2018

Rapid change now underway on Thwaites Glacier (TG) raises concern that a threshold for unstoppable grounding line retreat has been or is about to be crossed. We use a high‐resolution ice sheet model to examine the mechanics of TG self‐sustained retreat by nudging the grounding line just past the point of instability. We find that by modifying surface slope in the region of the grounding line, the rate of the forcing dictates the rate of retreat, even after the external forcing is removed. Grounding line retreats that begin faster proceed more rapidly because the shorter time interval for the grounding line to erode into the grounded ice sheet means relatively thicker ice and larger driving stress upstream of the boundary. Retreat is sensitive to short‐duration re‐advances associated with reduced external forcing where the bathymetry allows regrounding, even when an instability is invoked.
Big Jump of Record Warm Global Mean Surface Temperature in 2014–2016 Related to Unusually Large Oceanic Heat Releases
Authors: Yin Jianjun , Overpeck Jonathan , Peyser Cheryl , Stouffer Ronald
Published: January 2018

A 0.24°C jump of record warm global mean surface temperature (GMST) over the past three consecutive record‐breaking years (2014–2016) was highly unusual and largely a consequence of an El Niño that released unusually large amounts of ocean heat from the subsurface layer of the northwestern tropical Pacific. This heat had built up since the 1990s mainly due to greenhouse‐gas (GHG) forcing and possible remote oceanic effects. Model simulations and projections suggest that the fundamental cause, and robust predictor of large record‐breaking events of GMST in the 21st century, is GHG forcing rather than internal climate variability alone. Such events will increase in frequency, magnitude, and duration, as well as impact, in the future unless GHG forcing is reduced.
Hybrid Organic/PbS Quantum Dot Bilayer Photodetector with Low Dark Current and High Detectivity
Authors: Wei Yuanzhi , Ren Zhenwei , Zhang Andong , Mao Peng , Li Hui , Zhong Xinhua , Li Weiwei , Yang Shiyong , Wang Jizheng
Published: January 2018

Owing to their ease of fabrication, low cost, and high flexibility, organic materials have attracted great interests in photodetector (PD) applications. However, suffering from large dark current, small photocurrent, low on–off ratio, and low sensitivity, performances of bare organic‐based PDs are not satisfactory. Integrating organic materials with other novel semiconductor materials offers an opportunity to overcome these drawbacks. Here, a lateral hybrid organic/lead sulfide (PbS) quantum dot bilayer PD is designed and fabricated, which significantly suppresses the dark current and enhances the photocurrent, leading to improved light detecting capability. Meanwhile, the bilayer PD can be made on a flexible polyimide substrate.
Double‐Emulsion‐Templated Anisotropic Microcapsules for pH‐Triggered Release
Authors: Kim Bomi , Lee Sangmin , Kim Shin‐Hyun
Published: January 2018

Biocompatible microcapsules with a function of pH‐triggered release are promising for the site‐specific release of bio‐actives in the human body. In this work, smart microcapsules with three distinct configurations of membranes are produced to control the rate of pH‐triggered release. The microcapsules are prepared with a template of water‐in‐oil‐in‐water double‐emulsion drops. The oil shells of drops contain two polymers dissolved in an organic solvent: one is a biodegradable polymer selected from poly(lactic acid), poly(lactic‐co‐glycolic acid), and polycaprolactone, and the other is a pH‐responsive cationic polymer. Upon the depletion of organic solvent, two polymers confined in the shell undergo phase separation and double‐emulsion drops transform to microcapsules with the solid membrane. Three different configurations of the membranes − spherical, snowman‐like, and eyeball‐like structures − are exclusively produced according to the selection of biodegradable polymers. Although all the microcapsules release hydrophilic encapsulant loaded in the core when they are subjected to a weakly acidic condition, the release kinetics strongly depends on the configuration of the membrane. Larger surface coverage and thinner membrane of pH‐responsive domains result in faster release.
Efficient Ternary Polymer Solar Cells with Two Well‐Compatible Donors and One Ultranarrow Bandgap Nonfullerene Acceptor
Authors: Ma Xiaoling , Mi Yang , Zhang Fujun , An Qiaoshi , Zhang Miao , Hu Zhenghao , Liu Xinfeng , Zhang Jian , Tang Weihua
Published: January 2018

Nonfullerene polymer solar cells (PSCs) are fabricated by using one wide bandgap donor PBDB‐T and one ultranarrow bandgap acceptor IEICO‐4F as the active layers. One medium bandgap donor PTB7‐Th is selected as the third component due to the similar highest occupied molecular orbital level compared to that of PBDB‐T and their complementary absorption spectra. The champion power conversion efficiency (PCE) of PSCs is increased from 10.25% to 11.62% via incorporating 20 wt% PTB7‐Th in donors, with enhanced short‐circuit current (JSC) of 24.14 mA cm−2 and fill factor (FF) of 65.03%. The 11.62% PCE should be the highest value for ternary nonfullerene PSCs. The main contribution of PTB7‐Th can be summarized as the improved photon harvesting and enhanced exciton utilization of PBDB‐T due to the efficient energy transfer from PBDB‐T to PTB7‐Th. Meanwhile, PTB7‐Th can also act as a regulator to adjust PBDB‐T molecular arrangement for optimizing charge transport, resulting in the enhanced FF of ternary PSCs. This experimental result may provide new insight for developing high‐performance ternary nonfullerene PSCs by selecting two well‐compatible donors with different bandgap and one ultranarrow bandgap acceptor.
Battery‐like Supercapacitors from Vertically Aligned Carbon Nanofiber Coated Diamond: Design and Demonstrator
Authors: Yu Siyu , Yang Nianjun , Vogel Michael , Mandal Soumen , Williams Oliver A. , Jiang Siyu , Schönherr Holger , Yang Bing , Jiang Xin
Published: January 2018

To fabricate battery‐like supercapacitors with high power and energy densities, big capacitances, as well as long‐term capacitance retention, vertically aligned carbon nanofibers (CNFs) grown on boron doped diamond (BDD) films are employed as the capacitor electrodes. They possess large surface areas, high conductivity, high stability, and importantly are free of binder. The large surface areas result from their porous structures. The containment of graphene layers and copper metal catalysts inside CNFs leads to their high conductivity. Both electrical double layer capacitors (EDLCs) in inert solutions and pseudocapacitors (PCs) using Fe(CN)63−/4− redox‐active electrolytes are constructed with three‐ and two‐electrode systems. The assembled two‐electrode symmetrical supercapacitor devices exhibit capacitances of 30 and 48 mF cm−2 at 10 mV s−1 for EDLC and PC devices, respectively. They remain constant even after 10 000 charging/discharging cycles. The power densities are 27.3 and 25.3 kW kg−1 for EDLC and PC devices, together with their energy densities of 22.9 and 44.1 W h kg−1, respectively. The performance of these devices is superior to most of the reported supercapacitors and batteries. Vertically aligned CNF/BDD hybrid films are thus useful to construct high‐performance battery‐like and industry‐orientated supercapacitors for future power devices.
A rare male patient with classic Rett syndrome caused by MeCP2_e1 mutation
Authors: Tokaji Narumi , Ito Hiromichi , Kohmoto Tomohiro , Naruto Takuya , Takahashi Rizu , Goji Aya , Mori Tatsuo , Toda Yoshihiro , Saito Masako , Tange Shoichiro , Masuda Kiyoshi , Kagami Shoji , Imoto Issei
Published: January 2018

Rett syndrome (RTT) is a severe neurodevelopmental disorder typically affecting females. It is mainly caused by loss‐of‐function mutations that affect the coding sequence of exon 3 or 4 of methyl‐CpG‐binding protein 2 (MECP2). Severe neonatal encephalopathy resulting in death before the age of 2 years is the most common phenotype observed in males affected by a pathogenic MECP2 variant. Mutations in MECP2 exon 1 affecting the MeCP2_e1 isoform are relatively rare causes of RTT in females, and only one case of a male patient with MECP2‐related severe neonatal encephalopathy caused by a mutation in MECP2 exon 1 has been reported. This is the first reported case of a male with classic RTT caused by a 5‐bp duplication in the open‐reading frame of MECP2 exon 1 (NM_001110792.1:c.23_27dup) that introduced a premature stop codon [p.(Ser10Argfs*36)] in the MeCP2_e1 isoform, which has been reported in one female patient with classic RTT. Therefore, both males and females displaying at least some type of MeCP2_e1 mutation may exhibit the classic RTT phenotype.