bluuebunny/crossref_metadata_2025 huggingface dataset:
Estudo comparativo de instrumentos de autoavaliação para triagem de casos de hanseníase: revisão integrativa
Authors: Costa Letícia Gomes , Ignotti Eliane , Frade Marco Andrey Cipriani , Lima Nelzabete Silvino da Silva
Published: May 2024

Objetivo: Revisar a literatura quanto à utilização de instrumentos de autoavaliação para triagem de casos de hanseníase. Métodos: pesquisa conduzida nas bases de dados eletrônicas US National Library of Medicine (PubMed), Biblioteca Virtual em Saúde (BVS), e em documentos dos sites governamentais do Ministério da Saúde; Organização Mundial da Saúde; Organização Pan-americana de Saúde; Sites das Secretarias Estaduais e municipais de Saúde do Brasil; bem como em documentos de sites não governamentais: Parceria Global por Zero Hanseníase; Fundação Novartis e Netherlands Leprosy Relief. Os artigos selecionados nas bases de dados eletrônicas foram transferidos e analisados no aplicativo Rayyan para identificação e quantificação de duplicidades. Resultados: Foram identificados 3 instrumentos de autoavaliação em hanseníase: a Ficha de Autoimagem do Ministério da Saúde do Brasil, o Questionário de Suspeição de Hanseníase (QSH), dos pesquisadores brasileiros Bernardes Filho e Frade e o Instrumento de Autotriagem utilizado na Indonésia. Dentre os três, o mais completo é o QSH. Considerações finais: os instrumentos de autoavaliação em hanseníase demonstraram ser uma ferramenta aliada à detecção de casos em diferentes contextos epidemiológicos, configuram-se como material educativo e facilitam a triagem de casos a serem priorizados no exame dermatoneurológico em abordagens populacionais.
Additive aluminum as a cause of induced immunoexcitoxicity resulting in neurodevelopmental and neurodegenerative disorders: A biochemical, pathophysiological, and pharmacological analysis
Authors: Blaylock Russell L.
Published: May 2024

Much has been learned about the neurotoxicity of aluminum over the past several decades in terms of its ability to disrupt cellular function, result in slow accumulation, and the difficulty of its removal from cells. Newer evidence suggests a central pathophysiological mechanism may be responsible for much of the toxicity of aluminum and aluminofluoride compounds on the brain and spinal cord. This mechanism involves activation of the brain’s innate immune system, primarily the microglia, astrocytes, and macrophages, with a release of neurotoxic concentrations of excitotoxins and proinflammatory cytokines, chemokines, and immune mediators. Many studies suggest that excitotoxicity plays a significant role in the neurotoxic action of several metals, including aluminum. Recently, researchers have found that while most of the chronic pathology involved in the observed neurodegenerative effects of these metals are secondary to prolonged inflammation, it is the enhancement of excitotoxicity by the immune mediators that are responsible for most of the metal’s toxicity. This enhancement occurs through a crosstalk between cytokines and glutamate-related mechanisms. The author coined the name immunoexcitotoxicity to describe this process. This paper reviews the evidence linking immunoexcitotoxicity to aluminum’s neurotoxic effects and that a slow accumulation of aluminum may be the cause of neurodevelopmental defects as well as neurodegeneration in the adult.
Microvascular decompression is effective for oculomotor nerve palsy caused by posterior cerebral artery compression: A case report
Authors: Takeuchi Youhei , Arai Hiroaki , Endo Toshiki , Shibuya Satoshi , Ohtomo Satoru , Endo Hidenori
Published: May 2024

Background:

Oculomotor nerve palsy is often associated with diabetes mellitus or caused by compression by a cerebral aneurysm. Here, we report a rare case of oculomotor nerve palsy caused by compression by the posterior cerebral artery (PCA).

Case Description:

A 66-year-old woman suddenly developed diplopia and right blepharoptosis. Her symptoms suggested incomplete right oculomotor nerve palsy. Magnetic resonance imaging showed that a sharp curve in the right PCA had compressed the right oculomotor nerve. Microvascular decompression surgery was performed. Intraoperative findings showed that the P2 portion of the PCA had caused an indentation in the oculomotor nerve in the prepontine cistern. The transposition of the PCA with a prosthesis released the pressure. After the operation, her right blepharoptosis gradually improved. She had fully recovered by 48 days after the operation.

Conclusion:

Neurovascular compression (NVC) is recognized as the cause of hemifacial spasms, trigeminal neuralgia, and glossopharyngeal neuralgia. This case report demonstrated that NVC can also cause oculomotor nerve palsy. A high index of clinical suspicion can detect vascular compression of the oculomotor nerve. Prompt diagnosis and appropriate surgical management can achieve clinical improvement.
Does Machine Learning Learn the Physics for Pose Ranking of Fragment-Sized Ligands? A Comparison between Machine Learning and Physics-based Methods
Authors: wan xiao , Xue Bai , Bellucci Michael , Lin Zhixiong , Yang Mingjun , Zou Junjie
Published: May 2024

In fragment-based drug discovery using in silico methods, predicting the binding pose is a crucial step to ensure the accurate prediction of binding affinities. Recent studies have focused on the challenges of docking fragments compared to drug-like molecules, with findings suggesting that more sophisticated scoring functions can improve the accuracy of identifying correct binding poses. In this work, we conducted extensive ABFEP (Alchemical Binding Free Energy Perturbation) calculations on a fragment benchmarking dataset to evaluate the accuracy of ABFEP in ranking binding poses of fragments and compared ABFEP rescoring with Vina and two machine learning (ML)-based scoring functions. Indeed, ABFEP, which has a theoretically more rigorous scoring function, significantly outperforms Vina. In-depth comparison between ML-based scoring functions and ABFEP shows that ML-based scoring functions behave similarly to ABFEP on the prediction accuracy and failed cases, indicating that ML is capable of increasing the prediction accuracy over traditional scoring functions through learning the underlying physics rather than memorizing the coordinates in the training data.
Accelerating Density Matrix Embedding with Stochastic Density Fitting Theory – An Application to Hydrogen Bonded Clusters
Authors: Sun Yi
Published: May 2024

We demonstrate how using semi-stochastic Density Fitting (ss-DF) can accelerate self-consistent Density Matrix Embedding Theory (DMET) calculations by reducing the number of auxiliary orbitals in the three-indexed DF integrals. This results in time savings in building the Hartree Fock (HF) Coulomb and the Exchange Matrix and in integral transformation from the Atomic Orbital (AO) basis to the Embedding orbital (EO) basis. We then apply ss-DF to a range of hydrogen bonded clusters. First, we examine how the amount of deterministic space impacts the quality of the calculation in a $\left(\mathrm{H}_{2} \mathrm{O}\right)_{10}$ cluster. Next, we test the computational efficiency of ss-DF when compared to deterministic DF (d-DF) in water clusters containing 6 to 30 molecules of water using a triple-$\zeta$ basis set. Finally, we perform numerical structural optimisations on water and hydrogen fluoride clusters, revealing that DMET can recover weak interactions when using a back-transformed energy formula. This work therefore demonstrates the potential of using stochastic resolution of identity in quantum embedding theories and their potential to recover weak interactions.
Increasing Atomic Electron Cloud Density Leads to Formation of Body Centered Cubic (BCC) Gold
Authors: Gu Hengfei , Ren Jie , Wu Songquan , Li Mingyuan , Zhang Lifeng , Liu Chengze , Yuan Fusen , Han Fuzhou , Zhang Yingdong , Ali Muhammad , Guo Wenbin , Li Geping
Published: May 2024

Most metallic elements possess one relatively close packed structure of body-centered cubic (BCC), face-centered cubic (FCC) and hexagonal close packed (HCP) structures. Access to these structures as a function of temperature and pressure varies for different groups in the periodic table. Under low pressures, the copper group elements (copper (Cu), silver (Ag) and gold (Au)) only has a FCC structure regardless of temperatures. Recently, BCC Au was detected under extreme compression. The structural preference for a given metal element is still not understood. In this work, we surprisingly observed formation of BCC Au from amorphous Au as well as FCC Au within an electron self-transferred Au nanoparticle supported by our synthesized zirconium hydroxide nitrate tube. We propose a theory behind this unexpected phase formation: the increase in atomic electron cloud densities of Au atoms enabled by the electron transfer contributes more free electrons over the Au nanoparticle, enhancing metallic bonding strength to hold Au atoms closer to form a BCC structure that can store denser electron states within a Fermi sphere in first Brillouin zone as compared to FCC Au. This can also explain formation of BCC Au under compression. Our theory and strategy can guide how to expand the structure world of metals under ambient conditions for beneficial applications.
Chemiexcitation Acceleration of 1,2-Dioxetanes via a Spiro-Fused Inductive Electron-Withdrawing Motifs
Authors: David Maya , Leirikh Thomas , Shelef Omri , Gutkin Sara , Kopp Tal , Zhou Qingyang , Ma Pengchen , Fridman Micha , Houk Kendall , Shabat Doron
Published: May 2024

The chemiluminescent light-emission pathway of phenoxy-1,2-dioxetane luminophores attracts growing interest within the scientific community. Dioxetane probes undergoing rapid flash-type chemiexcitation exhibit higher detection sensitivity than those with a slow glow-type chemiexcitation rate, predominantly due to the higher number of photons produced within a given time interval. We discovered that dioxetanes fused to non-strained six-member rings, with hetero atoms or inductive electron-withdrawing groups, present both accelerated chemiexcitation rates and elevated chemical stability compared to dioxetanes fused to four-member strained rings. DFT computational simulations supported the chemiexcitation acceleration observed by spiro-fused six-member rings with inductive electron-withdrawing groups of dioxetanes. Specifically, a spiro-dioxetane with a six-member sulfone ring exhibited a chemiexcitation rate 293-fold faster than that of spiro-adamantyl-dioxetane. A turn-ON dioxetane probe for the detection of the enzyme β-galactosidase, containing the six-member sulfone unit, exhibited a S/N value of 108 in LB cell growth media. This probe demonstrated a substantial increase in detection sensitivity towards E. coli bacterial cells expressing β-galactosidase, with an LOD value that is 44-fold more sensitive than that obtained by the adamantyl counterpart. The accelerated chemiexcitation and the elevated chemical stability presented by dioxetane containing a spiro-fused six-member ring with a sulfone inductive electron-withdrawing group, make it an ideal candidate for designing efficient turn-on chemiluminescent probes with exceptionally high detection sensitivity.
Self-Nanoformulating Poly(2-oxazoline) and Poly(2-oxazine) Copolymers Based Amorphous Solid Dispersions as Microneedle Patch: A Formulation Study
Authors: D´Amico Carmine , Ziegler Anna-Lena , Kemell Marianna , Molinaro Giuseppina , Luxenhofer Robert , Santos Hélder
Published: May 2024

Here, we introduce a pioneering approach in the domain of transdermal drug delivery systems (TDDS) by using microneedles (MNs) fabricated from amorphous solid dispersion comprising only a model drug and an amphiphilic block copolymer to form a drug nanoformulation upon MN dissolution. This approach presents the most minimalistic approach to maximize drug loading in MN, reaching 40 wt.%. Using scanning electron microscopy, we carefully examined the morphology of MNs across a spectrum of drug loading ratios, revealing a remarkable consistency in structure and integrity. Mechanical testing confirms the MNs' proficiency in effective skin penetration. Furthermore, a comparative study on the formation of polymeric micelles underscores the innovative concept of a “nano-in-micro drug delivery system”, offering an approach to drug release. The results demonstrate that MNs manufactured from an amorphous solid dispersion of drug and amphiphilic block copolymer with ultra-high loading, enhancing the availability and release dynamics of hydrophobic drugs, positioning them as a potent tool for enhancing TDDS. This study sets a new benchmark in the utilization of polymer-drug nanoformulations for transdermal applications and underscores the exceptional capacity for high drug loading and the creation of adaptable drug delivery mechanisms for the studied amphiphilic block copolymer.
Metal–Water Interface Formation: Thermodynamics from Ab-Initio Molecular Dynamics Simulations
Authors: Domínguez-Flores Fabiola , Kiljunen Toni , Groß Axel , Sakong Sung , Melander Marko M.
Published: May 2024

Metal–water interfaces are central to many electrochemical, (electro)catalytic, and materials science processes and systems. However, our current understanding of their thermodynamic properties is limited by the scarcity of accurate experimental and computational data and procedures. In this work, thermodynamic quantities for metal–water interface formation are computed for a range of FCC(111) surfaces (Pd, Pt, Au, Ag, Rh, and PdAu) through extensive density functional theory based molecular dynamics and the two-phase entropy model. We show that metal–water interface formation is thermodynamically favorable and that most metal surfaces studied in this work are completely wettable, i.e., have contact angles of zero. Interfacial water has higher entropy than bulk water due to the increased population of low-frequency translational modes. The entropic contributions also correlate with the orientational water density and the highest solvation entropies are observed for interfaces with a moderately ordered first water layer; the entropic contributions account for up to ca. 25 % of the formation free energy. Water adsorption energy correlates with the water orientation and structure, and is found to be a good descriptor of the internal energy part of the interface formation free energy but it alone cannot satisfactorily explain the interfacial thermodynamics; the interface formation is driven by the competition between energetic and entropic contributions. The obtained results and insight can be used to develop, parametrize, and benchmark theoretical and computational methods for studying metal–water interfaces. Overall, our study yields benchmark-quality data and fundamental insight into the thermodynamic forces driving metal–water inter- face formation.
Constrained synthesis planning with disconnection-aware transformer and multi-objective search
Authors: Westerlund Annie M. , Saigiridharan Lakshidaa , Genheden Samuel
Published: May 2024

Designing synthesis routes with shared intermediates for a set of target compounds is a common task in drug discovery. Multistep retrosynthesis tools such as AiZynthFinder are frequently used by chemists to generate possible routes. Although these tools can find solved routes for a majority of target compounds, they may not generate routes which comply with specific bond constraints. Such bond constraints could be defined in the project to obtain synthesis routes with common intermediates for the set of compounds. Here, we present a novel retrosynthesis approach which aims to generate routes in the feasible region defined by these constraints. The constraints are divided into bonds to break and bonds to freeze. First, we introduce a filter in the search which discards any reaction that violates the frozen bond constraints. Second, we benchmark four possible strategies for breaking selected bonds in the search for synthetic routes. We show that a combination of disconnection-aware transformer and multi-objective search generates routes which satisfy bond constraints for more targets in the PaRoutes dataset compared to the standard search (75.57% vs. 54.80%). Finally, we apply the strategy on a set of drug compounds to exemplify a real-world scenario. Using our novel approach, we can build a short joint synthesis route which satisfies the given bond constraints and covers eight of the ten compounds.
Development of Complete Enumeration Program for Polymer Structural Isomers: A Case of Nylon-n (n = 3-10)
Authors: Usuki Gikyo , Tsutsumi Takuro , Hasebe Kohei , Kobayashi Masato , Matsuoka Keitaro , Taketsugu Tetsuya , Sada Kazuki
Published: May 2024

The enumeration of structural isomers of organic molecules using programs capable of enumerating all structural isomers for a given molecular formula has been expanding the chemical library. Here, we report the development of the program (PolyENU) that completely enumerates polymer structural isomers. PolyENU program enumerates all isomers of the repeating unit defined by a molecular formula and a functional group constituting the polymer structure. From the repeating unit of nylon 6 (C6H11NO and an amide group), 387 polymer isomers were generated by PolyENU. The enumerated polymer library includes common organic polymers such as nylon 6, polyleucine, poly(2-isopropyl-oxazoline), and poly(N-propylacrylamide), as well as many unexplored polymers. The enumeration of nylon n (n = 3-10) yielded 36,505 polymers within 44 minutes. These results clearly indicate that PolyENU expands polymer chemical space and contributes to diversity in polymer science.
Transducing chemical energy through catalysis by an artificial molecular motor
Authors: Wang Peng-Lai , Borsley Stefan , Power Martin , Cavasso Alessandro , Giuseppone Nicolas , Leigh David
Published: May 2024

Cells display a range of mechanical activities enabled by the cytoskeleton, a viscoelastic hydrogel manipulated by motor proteins powered through catalysis. This raises the question of how the acceleration of a chemical reaction can enable the energy released from that reaction to be transduced, and thereby work to be done, by a molecular catalyst. Here we demonstrate the molecular-level transduction of chemical energy to mechanical force in the form of the powered contraction and powered re-expansion of a crosslinked polymer gel driven by the directional rotation of embedded artificial catalysis-driven molecular motors. Continuous 360° rotation of the rotor about the stator of motor-molecules incorporated within the polymeric framework of the gel, twists the polymer chains of the crosslinked network around one another (either clockwise or anti-clockwise, depending on the chirality of the fuelling system). This progressively increases writhe and tightens entanglements, causing macroscopic contraction of the gel to ~70% of its original volume. The limit of contraction corresponds to the stall force of the motor; the point at which, despite catalysis continuing, the untwisting force exerted by the entwined strands balances conformation selection in the motor’s catalytic cycle. Subsequent addition of the opposite enantiomeric fuelling system powers rotation of the motor-molecules of the contracted gel in the reverse direction, unwinding the entanglements and causing the gel to re-expand. Continued powered twisting of the strands in the new direction causes the gel to contract once again. The experimental demonstration of work against a load by a synthetic catalyst, and the mechanism of the transduction of energy by a catalyst through kinetic asymmetry in its acceleration of a fuel-to-waste reaction, informs both the debate surrounding the mechanism of force generation by biological motors and the design principles for artificial molecular nanotechnology.
Feedback-aligned Mixed LLMs for Machine Language-Molecule Translation
Authors: Gkoumas Dimitris , Liakata Maria
Published: May 2024

The intersection of chemistry and Artificial Intelligence (AI) is an active area of research focused on accelerating scientific discovery. While using large language models (LLMs) with scientific modalities has shown potential, there are significant challenges to address, such as improving training efficiency and dealing with the out-of-distribution problem. Focussing on the task of automated language-molecule translation, we are the first to use state-of-the art (SOTA) human-centric optimisation algorithms in the cross-modal setting, successfully aligning cross-language-molecule modals. We empirically show that we can augment the capabilities of scientific LLMs without the need for extensive data or large models. We conduct experiments using only 10% of the available data to mitigate memorisation effects associated with training large models on extensive datasets. We achieve significant performance gains, surpassing the best benchmark model trained on extensive in-distribution data by a large margin and reach new SOTA levels. Additionally we are the first to propose employing non-linear fusion for mixing cross-modal LLMs which further boosts performance gains without increasing training costs or data needs. Finally, we introduce a fine-grained, domain-agnostic evaluation method to assess hallucination in LLMs and promote responsible use.
Ordered Transfer from 3D-oriented MOF Superstructures to Polymeric Films: Microfabrication, Enhanced Chemical Stability, and Anisotropic Fluorescent Patterns
Authors: Brandner Lea A. , Marmiroli Benedetta , Linares-Moreau Mercedes , Barella Mariano , Abbasgholi-NA Behnaz , Velásquez-Hernández Miriam de J. , Flint Kate L. , Dal Zilio Simone , Acuna Guillermo P. , Wolinski Heimo , Doonan Christian J. , Falcaro Paolo
Published: May 2024

Films and patterns of 3D-oriented metal-organic frameworks (MOFs) afford well-ordered pore structures extending across centimeter-scale areas. These macroscopic domains of aligned pores are pivotal to enhance diffusion along specific pathways and orient functional guests. The anisotropic properties emerging from this alignment are beneficial for applications in ion conductivity and photonics. However, the structure of 3D-oriented MOF films and patterns can rapidly degrade under humid and acidic conditions. Thus, more durable 3D-ordered porous systems are desired for practical applications. Here, oriented porous polymer films and patterns are prepared by using heteroepitaxially oriented N3-functionalized MOF films as precursor materials. The film fabrication protocol utilizes an azide–alkyne cycloaddition on the Cu2(AzBPDC)2DABCO MOF. The micropatterning protocol exploits the X-ray sensitivity of azide groups in Cu2(AzBPDC)2DABCO, enabling selective degradation in the irradiated areas. The masked regions of the MOF film retain their N3-functionality, allowing for subsequent cross-linking through azide-alkyne coupling. Subsequent acidic treatment removes the Cu ions from the MOF, yielding porous polymer micro-patterns. The polymer has high chemical stability and shows an anisotropic fluorescent response. The use of 3D-oriented MOF systems as precursors for the fabrication of oriented porous polymers will facilitate the progress of optical components for photonic applications.
Ninguém faz samba porque prefere
Authors: Netto Ana Julia Toledo
Published: May 2024

A proposta deste artigo é analisar as influências das religiões afro-brasileiras, em particular a Umbanda, dentro da expressão musical nacional, com destaque para o samba. Expressão musical que se formou a partir do processo de assimilação, adaptação e deculturação dos ritmos e instrumentos africanos em contato com a cultura branca européia. Procura-se levantar algumas questões acerca das apropriações que inúmeros compositores fizeram e fazem das divindades do panteão afro e dos pontos cantados - cantigas umbandistas - em suas composições musicais.
Passado, presente e futuro do Som da Aura, uma criação de Hermeto Pascoal, com a colaboração de Jovino Santos Neto (1984-2022...)
Authors: Neto Luiz Costa-Lima
Published: May 2024

Este artigo utiliza como fontes principais o texto inédito escrito originalmente pelo compositor e pianista Jovino Santos Neto, em 1992, além da entrevista por nós realizada com o músico em 08 de abril de 2022, sobre o Som da Aura, denominação criada pelo compositor e arranjador brasileiro Hermeto Pascoal para designar composições musicais baseadas na noção de que a voz falada é uma melodia não-convencional. Por meio de pesquisa documental e etnográfica, apresentamos informações sobre a gênese, o desenvolvimento e os desdobramentos do Som da Aura, desde a década de 1980 até a atualidade, mostrando aplicações desse tipo de composição na música, no audiovisual, no teatro e em obras multimídia.
Personas Plásticas
Authors: Desideri Marcio
Published: May 2024

Através da linguagem da maquiagem nas artes da cena, estudamos os seus desdobramentos com as novas tecnologias, o seu campo expandido, como a proliferação de personas plásticas, a relação de in(corporação) com o corpo animado e inanimado, a virtualidade e a sua voz polifônica. Analisamos as redes de criação que a circundam, as divergências e as convergências, em diferentes processos criativos, no cinema, teatro e vídeo performance. Além de observar o uso de próteses e sua reprodutibilidade. Em seguida, refletimos sobre os questionamentos, aqui encontrados, sobre a maquiagem e suas vozes através das artes da cena.
Editorial / Apresentação
Authors: Lignelli César , Dordete Daiane , Vargens Meran , Mundim Tiago Elias
Published: May 2024

Editorial / Apresentação
por César Lignelli, Daiane Dordete, Meran Vargens e Tiago Mundim
Em ritmo intenso de celebração apresentamos o número 02 do ano de 2022 da Revista Voz e Cena. Esbanjamos motivos para festejar, uma vez que, para além das tradicionais comemorações de final de ano, enquanto colaboradores deste periódico conseguimos chegar até aqui com a resiliência que se fez necessária; enquanto representantes das Instituições de Ensino parceiras de nossa revista tivemos a oportunidade de nos encontrar presencialmente no X Seminário A Voz e a Cena, em edição que ocorreu pela primeira vez na região norte do país, no estado do Acre; enquanto pessoas pertencentes a essa nação estamos prestes a respirar outros ares;  e ainda com este número, mesmo que parcialmente, exaltamos ressonâncias conceituais e estéticas de parte significativa das pesquisas do artista, professor, pesquisador Ernani Maletta.  
Para tal, apresentamos o Dossiê Temático Polifonia nas Artes da Cena organizado por comissão editorial composta por Ernani Maletta professor da Universidade Federal de Minas Gerais (UFMG), César Lignelli professor da Universidade de Brasília (UnB), Jussara Fernandino professora da Universidade Federal de Minas Gerais (UFMG) e Vinícius Assunção Albricker, professor da Universidade Federal do Estado do Rio de Janeiro (UNIRIO).
Em seu conjunto, este número conta com 11 (onze) artigos, sendo 1 (um) escrito originalmente em italiano, e 4 (quatro) entrevistas, sendo que 1 (uma) dessas foi realizada originalmente em inglês, não compõe o Dossiê Temático Polifonia nas Artes da Cena e trata dos exercícios vocais e dos princípios metodológicos no trabalho do ator, na perspectiva de Zygmunt Molik. 
Aproveitamos o ensejo para agradecer ao PPG-CEN/UnB e à CAPES pelo apoio institucional, aos integrantes da Rede Voz e Cena e às nossas parcerias interinstitucionais via professoras e professores atuantes nos cursos técnicos, de graduação e de pós-graduação em Artes Cênicas da Universidade de Brasília (UnB), da Universidade Federal Grande Dourados (UFGD), da Universidade Federal do Acre (UFAC), da Universidade Federal de Pernambuco (UFPE), da Universidade Federal da Paraíba (UFPB), da Universidade Federal da Bahia (UFBA), da Universidade Federal do Estado do Rio de Janeiro (UNIRIO), da Universidade Estadual de São Paulo (UNESP), da Universidade Federal de Minas Gerais (UFMG), da Universidade do Estado de Santa Catarina (UDESC), da Escola de Arte Dramática (EAD/ECA/USP), da Universidade Federal de Ouro Preto (UFOP), da Universidade Federal de Uberlândia (UFU) da Universidade Federal de Santa Catarina (UFSC) e da Universidade Federal de São João Del Rei (UFSJ).
Por fim, reiteramos a importância da leitura e da utilização de nossos artigos e entrevistas, sobretudo em pesquisas relacionadas às sonoridades e às artes da cena, para que possamos dar continuidade à revista e, cada vez mais, melhorar a qualidade de nossas publicações.
The Keeper of My Memories
Authors:   , Williams Beth
Published: May 2024

The Keeper of My Memories explores architecture within a narrative that bridges the built world and our imagined spaces. This thesis uses the imagined worlds created throughout my life to question, what if childhood daydreaming can be harnessed through architectural narrative so that real and imaginary realms are bridged, sparking moments of reverie and nostalgia? Design-led research is used to explore the research question. Firstly, research-for-design is used to provide a theoretical context and case study analysis, situating the idea of architecture as part of a narrative to enhance the lives of occupants. Secondly, the methodology of research-through-design is used as an iterative design process. The research question is addressed through a narrative methodology, both visually and through supplementary writing. The narrative methodology uses methods of drawing, painting, physical model making and digital Blender models. Research-through-design explores the development of three designed outcomes, presented as part of an overall story, in Chapters Four, Five and Six. Each design chapter increases in detail and scale as the story is told through architecture. Chapter Four, the installation, operates at the miniature scale of the body, acting as a tool to transport the viewer to the imagined realm, invoking the reverie. It follows a model maker as they construct a doll’s house. Chapter Five scales up to the domestic, creating a house at Lime Road and presenting an architecture that is not static. Over time, the house develops alongside the seven characters who reside within it. Chapter Six scales up to a public-scale building by constructing a film set within the reality created in Chapter Five. As a result, the characters at Lime Road become actors in the film, and the house becomes the film set. The Keeper of My Memories is an architectural fantasy that considers imaginary worlds and the architecture within them. This thesis reclaims the worlds constructed within children’s imagination and uses architecture to tether these worlds to a perception of reality.
Explore the Application of Machine Vision Technology in the Automation of Machinery Manufacturing
Authors: Chen Yujie
Published: May 2024

The continuous acceleration of China’s industrialization process has made automation and intelligent technologies increasingly dominant. Implementing these technologies can enhance machining and production efficiency, free up manpower, automate machinery manufacturing processes, and yield greater economic benefits. Thus, this paper outlines the key applications of machine vision technology in modern machinery manufacturing automation. It discusses how machine vision can contribute to core functions such as workpiece measurement, detection, and robot welding, facilitating automation, intelligence, and sustainable development. The aim is for the findings of this paper to offer valuable insights into relevant professions and production processes, thereby catalyzing the pace of mechanical manufacturing automation.
Analysis of Intelligent Financial Management Systems in Enterprises
Authors: Peng Yumin
Published: May 2024

With the advent of the era of artificial intelligence, traditional corporate financial management cannot adapt to the rapid development of modern economic society and scientific and technological progress. Therefore, they need to pay more attention to digital transformation and artificial intelligence. Artificial intelligence is a new technology that has changed the business and operation models of various industries and has put forward new requirements for corporate financial management. This paper explores the concept of intelligent finance, delves into the principles underlying intelligent financial management, discusses the significance of adopting intelligent financial management practices, and proposes a roadmap for constructing a intelligent financial management system.
Research on the Strategy of Artificial Intelligence Education in the Information Technology Curriculum of Primary and Secondary Schools
Authors: Zhao Dawei , Sun Xinlei
Published: May 2024

The development of science and technology has ushered in the era of artificial intelligence. This development affects school education in terms of information technology curriculum. The improvement of China’s national strength has led to the widespread of information technology education in primary and secondary schools. In this context, this paper studies artificial intelligence education in terms of its curriculum in primary and secondary schools.
Students’ Attitudes in Mathematics: When the Context Highlights the Importance of Emotions – A Secondary Publication
Authors: Genoud Philippe
Published: May 2024

This article aims to gain a better understanding of how students’ attitudes toward mathematical problem-solving operate. More specifically, it examines the extent to which these attitudes may play a different role depending on the context. To this end, we submitted two very similar golden rule math problems to 94 students in grade 10, once in the mathematics class and once in the French class. Our results are presented in three parts. First, in line with much other research, we highlight the significant gender differences in attitudes, with girls developing more negative and potentially deleterious attitudes to their learning. Second, we find significant links between various dimensions of attitudes (cognitive, affective, and behavioral) and students’ academic achievement in mathematics. Finally, our analyses underline that in the context of the mathematics course, it is mainly anxiety that disturbs the success of the exercise, whereas the resolution of a very similar exercise is favored by positive emotions when it is inserted into a French worksheet. This suggests that students activate certain attitudes depending on the context – and in particular certain affects – which will have an impact on their performance. Such a result thus underlines the importance of emotions in learning and the way in which the context can induce them.
A Study on the Construction Path of Campus Culture in Public Security Colleges with Hongyan Culture as the Background: A Case Study of Chongqing Police College
Authors: Quan Hualing , Li Tao , Peng Linquan , Wang Xianrong , Huang Qiao
Published: May 2024

This paper expounds on the feasibility of integrating Hongyan culture into the campus culture construction of public security colleges and universities, and takes Chongqing Police College as an example to analyze the current situation of integrating Hongyan culture into the campus culture construction of public security colleges and universities. It also puts forward measures and suggestions for accelerating the construction of campus culture construction based on Hongyan culture.
Analysis of GPS Technology in Surveying and Mapping Engineering Technology
Authors: Zhao Hanyu
Published: May 2024

With the rapid advancement of digital and information technology, global positioning system (GPS) technology has seen increasing utilization in surveying and mapping engineering, extending its application across land, ocean, and various other domains. By analyzing the technical means of GPS in surveying and mapping engineering, understanding the characteristics and key technologies in different application environments, and exploring the application process and key technical means, accurate control can be effectively realized. Based on this, this paper mainly analyzes the specific application of GPS technology in surveying and mapping engineering technology for reference.
Comparative evaluation of the promising lines of winter soft wheat in the south of the Rostov region
Authors: Chernova A. A. , Podgorny S. V. , Skripka O. V. , Chernova V. L. , Samofalov A. P.
Published: May 2024

The analysis of variability of winter soft wheat lines by quantitative traits is presented. The research was conducted in 2020–2023 in the Rostov region. Seven lines of winter soft wheat of the competitive variety trial were taken as an object of research. The Ermak variety was used as a standard. The yields of the lines during the years of study averaged from 9.78 to 10.12 t/ha with an average of 9.76 t/ha in the experiment. Plant height ranged from 85.0 to 115.0 cm. All the lines studied were classified as small- to medium-grained (32.9–45.9 g) in terms of 1000 grain weight. On average for the years of study, the minimum mass of 1000 grains was formed by the line 1638/19 (34.6 g), and the maximum – by the line 1361/19 (43.5 g). The lines had different groups of ripeness according to the indicator of the earing date. The spikelet length varied from 7.3 to 10.0 cm. The highest spikelet length was formed by the line 1361/19 (10.0 cm), the shortest – by the line 1120/19 (7.3 cm). The number of productive stems ranged from 471 to 924 stems/m2. The maximum number of productive stems for the years of the study was formed by the line 1921/20 (758 pcs./m2), the minimum –  by the line 1361/19 (689 pcs./m2). The number of grains per plant ranged from 61.6 to 110.6. On average, the highest number of grains per plant was formed by the line 1638/19 (100.6 pcs.), the lowest – 1343/19 (70.4 pcs.). The grain weight per plant averaged 3.54 g and ranged from 2.26 to 4.56 g. The number of grains per ear varied from 28.9 to 51.5 pieces, the maximum number was formed by the lines 1361/19 (42.7 pcs.) and 1638/19 (41.2 pcs.). In terms of the grain weight per ear the standard was exceeded by the line 1361/19 (1.93 g), the values for the indicator varied from 1.02 to 2.28 g.
Potato productivity on the background of the entomopathogenic fungus Metarhizium robertsii application in production trials
Authors: Shaldyaeva E. M. , Pilipova Yu. V. , Tomilova O. G. , Tyurin M. V. , Shmidt N. V. , Vasilenko N. V. , Glupov V. V.
Published: May 2024

For the first time in Western Siberia (Novosibirsk region), two-year production trials of an experimental prototype of a drug based on the entomopathogenic fungus Metarhizium robertsii have been conducted. Strain P-72 isolated from the dead larvae of Colorado potato beetle Leptinotarsa decemlineata Say from the collection of microorganisms of the Institute of Systematics and Ecology of Animals of the Siberian Branch of the Russian Academy of Sciences was used in this work. Species identification of the fungus was performed based on sequencing of the elongation factor gene region EF1α. The ability of the preparation to significantly increase the parameters of potato yield structure elements throughout the whole vegetation period was shown. A reliable increase in the number of surviving sprouts by 1.4 times, the number of stems and tubers by 1.5 times was found. The growth-stimulating effect of using the preparation based on entomopathogenic fungus was manifested in the increase of plant weight by the flowering phase. The average yield increase for two years amounted to 36.0% in the variant with application of M. robertsii significantly exceeding the productivity of potatoes in the control. The level of profitability of potato production with the use of entomopathogenic fungus M. robertsii increased to 92.0% (with 50.0% in the control) due to the increase in gross yield and improved quality of marketable products. Infestation of new harvest tubers with rhizoctoniose significantly decreased in the variant including treatment with entomopathogenic fungus: the number of tubers with sclerotia decreased 2.8 times compared to the control, which eventually led to an increase in the number of healthy tubers and a significant (2.5 times) decrease in the sclerotial index.
АВТОМАТИЗАЦІЯ ВНУТРІШНЬО-СКЛАДСЬКИХ ВИРОБНИЧИХ ЛОГІСТИЧНИХ ПРОЦЕСІВ ДЛЯ ВПРОВАДЖЕННЯ КОНЦЕПЦІЇ INDUSTRY 4.0: ЕНЕРГООЩАДЛИВІСТЬ, ПРОДУКТИВНІСТЬ, МОБІЛЬНІСТЬ, МОДУЛЬНІСТЬ, АВТОНОМНІСТЬ
Authors: Vzhesnievskyi M. , Chala O.
Published: May 2024

У статті розглянуто основні тенденції та завдання, що ставлять перед собою топові фірми основним профілем роботи яких є розробка, впровадження та підтримка систем внутрішноьскладскьої логістики. Основними критеріями на які в найближчому майбутньому будуть направлені розробки в сфері автоматизації виробничої внутрішньої логістики є енергоощадливість, продуктивність , мобільність, модульність та автономність. Доведено, що одним із основних шляхів удосконалення виробничих внотрішньоскладських логіститчних процесів є шатлові системи, що можуть бути модернізовані, шляхом використанням концепції кіберфізичних підходів. Це є один з найкоротших шляхів підвищення параметрів зменшення часу транспортування, сортування, зберігання та підвищення продуктивності, енергоефективності та гнучкості процесів виробничої внутрішньо складської логістики.
СУЧАСНІ ІНСТРУМЕНТИ ОРКЕСТРАЦІЇ ДАНИХ ДЛЯ ПОБУДОВИ КОНВЕЄРІВ АВТОМАТИЧНОЇ ОБРОБКИ ДАНИХ
Authors: Zaleskyi V. , Ivanovskii P. , Fedorchenko V.
Published: May 2024

Всесвіт даних у сучасних компаніях постійно розширюється. Зі збільшенням кількості даних збільшується потреба в управлінні, синхронізації розкладів та вирішення проблем обробки. Компаніям потрібно зламати бар'єри між джерелами даних та сховищами, щоб по-справжньому використовувати всю інформацію, яку вони збирають. Оркестрація даних дозволяє організаціям автоматизувати та оптимізувати свої дані, перетворюючи їх на оперативні активи, щоб цінну інформацію можна було використовувати для прийняття бізнес-рішень у режимі реального часу. За деякими оцінками, 80% роботи, пов'язаної з аналізом даних, зводиться до збирання та підготовки даних, що означає, що оркестрація даних може скоротити велику кількість часу на обробку та планування. Метою даної роботи є аналіз сучасних інструментів оркестрації. Об’єктом дослідження є дата інженерія. Предметом дослідження є оркестрація даних.
ДОСЛІДЖЕННЯ ЕФЕКТИВНОСТІ МЕТОДІВ ГЕНЕРАЦІЇ ТЕСТОВИХ ДАНИХ В РЕЛЯЦІЙНИХ БАЗАХ ДАНИХ
Authors: Minukhin S. , Bashkirov M.
Published: May 2024

У статті проведено порівняльний аналіз трьох основних методів генерації тестових даних для реляційних баз даних: циклічного, на основі Common Table Expressions (CTE) та з використанням тимчасових таблиць. Експериментальне тестування здійснено в середовищі MS SQL Server на прикладі таблиць бази даних торговельної компанії. Проведено порівняння за ключовими метриками ефективності генерації - часу генерації, використання системних ресурсів та масштабованістю об’ємів таблиць тестової бази даних. Результати дослідження обґрунтували ефективність методу рекурсивних CTE для різних обсягів і структур даних. Подано рекомендації щодо вибору методів генерації тестових наборів відповідно до вимог проектів БД, зокрема при використанні сервісів роботи з реляційними БД на хмарних платформах.
COMPARATIVE ANALYSIS OF THE APPLICATION OF HEURISTIC ALGORITHMS FOR SOLVING THE TSP PROBLEM
Authors: Skakalina О. , Kapiton A.
Published: May 2024

The need to solve the traveling salesman problem (TSP) often arises when solving practically significant optimization problems, such as problems in the field of economics, logistics in the widest range of applications, in chains of technical programs. Quite often, the specifics of these problems require obtaining a solution that is as close to the exact value as possible. But the TSP problem is NP-complex, that is, its exact solution can be obtained only in exponential time. Therefore, it is not efficient to solve the TSP problem by the full search algorithm in the presence of a large number of vertices of the graph. However, there are various heuristic algorithms that allow finding a rational solution to this problem with a large number of vertices in a time acceptable for the relevant subject area. In this work, the problem of the traveling salesman is defined as a mathematical programming task of finding the shortest path for the movement of a traveling salesman (traveling salesman), the goal of which is to visit all the objects involved in the task in the shortest time and with minimal costs. Appropriate adaptations of the heuristic algorithms, namely the genetic algorithm and the ant colony algorithm, were developed in the MATLAB environment. A computational experiment was performed on the same input sample, a comparative analysis of the performance of two heuristic algorithms, and the effectiveness of the use of heuristic algorithms for solving NP-complex problems was proven.
МАТЕМАТИЧНЕ МОДЕЛЮВАННЯ ПРОЦЕСІВ ОСАДЖЕННЯ ПИЛУ КАРБОНОВИХ КОМПОЗИТІВ ПРИ ШТУЧНІЙ ІОНІЗАЦІЇ ПОВІТРЯ РОБОЧОЇ ЗОНИ
Authors: Chencheva Olga
Published: May 2024

Мета. Математичне моделювання взаємодії аероіонів з різнофракційними пиловими частинками волокнистих карбонових композитів невизначеної геометричної, які мають у складі як елементи матриці, так і злами карбонових волокон. Методика. Моделювання здійснювалося шляхом виведення нових прогнозованих залежностей взаємодії аероіонів з елементами пилу, які ґрунтується на застосуванні рівнянь аеродинаміки, електростатики та масопереносу з урахуванням особливостей пилового та фракційного складу повітряного простору робочого середовища, а також емпіричного методу під час натурного експерименту та аналітичного аналізу отриманих результатів. Результати. Отримані результати дозволяють здійснювати оцінку аероіонного складу повітря та вплив на концентрацію пилу при використанні штучної іонізації повітря робочої зони. Наукова новизна. Розроблена математична модель поточної концентрації аероіонів при штучній іонізації повітря в робочій зоні під час механічної обробки карбонвмісних волокнистих композитів, яка враховує особливості утворення карбонового пилу, а саме геометричну форму пилових частинок та взаємодію елементів матриці і волокна композиційного матеріалу з аероіонами. Практична цінність. Використання штучної іонізації повітря робочої зони дозволяє прискорити процеси осадження виробничого пилу, який утворюється внаслідок механічної обробки волокнистих композиційних матеріалів, що дозволяє зменшити негативний вплив карбонового пилу на здоров’я працівників.
Arabic language (level A1 – A2. Conversation)
Authors: Akinina Olga , Zakryzhevsky Maxim , Yahya Mohannad
Published: May 2024

Textbook for the basic discipline “Second foreign language (Arabic)” of the curriculum in the direction of “International Relations”, developed according to MSU OS 3++ for the 2nd year students of the Faculty of Global Processes of Lomonosov Moscow State University. This issue contains materials for conversation on topics at the initial level of Arabic language proficiency, as well as socio-political texts of small volume and methodological recommendations for those who want to successfully pass an exam or take testing in Arabic at level A1 – A2. The textbook also includes questions for selfchecking, basic vocabulary and concepts, a list of recommended literature and Internet sources