bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of Nanoemulsion as Drugs Delivery Systems in Opthalmology: A Comprehensive Review
Authors: Chaudhary Amit , Shivalika Shivalika , Tomar Bhupendra , Kumar Verma Kapil
Published: August 2022

The opthalmic nanoemulsion drug delivery system is novel and advanced modes of drug delivery system. Nanoemulsions are oil in water type of emulsion and water in oil type of emulsion. The diameter of the drops range are 50 -1000nm (109m). The droplet size average range between 100-500nm. It is a part of widespread class of colloidal dispersion of multiphase. Nanoemulsions are accessible to formulate and upscale, and they appear high volatility in their constituents. They have turn out very feasible, cost effective, and non- invasive nanocarriers for intensify opthalmic delivery of a wide range of active compounds that influence to metabolize heavily or suffer from undesirable side effect when taken orally. In addition, the anti-viral and antimicrobial properties of nanoemulsion components, prominent to preservative free formulation, develop nanoemulsion very enticing path for ocular drug delivery. Thus the aim of this article is spotlight on nanoemulsion, various methods of preparation, characterization techniques, Also focus the mechanisms and strategies accomplished to effectively deliver drugs, both oil and water and water in oil nanoemulsion types, via the ocular way. The methods will be used to prepare for nanoemulsion are high energy method such as: high pressure Homoginization, Ultrasonication, Microfluidization. Evaluation parameters will be include particle size analysis, rheological measurement, refractive index, surface tension, viscosity, therapeutic efficacy study, in vitro release study and ocular irritation study respectively.
Almond (Prunus amygdalus Batsch.): A Latest Review on Pharmacology and Medicinal uses
Authors: Singh Diksha , J. Gohil Kashmira , T. Rajput Rekha , Sharma Vikash
Published: August 2022

Prunus amygdalus (Batsch.) is an important medicinal plant and belongs to the family Rosaceae. It is known as Badam in Hindi and almond in English. The nutritional and medicinal properties of badam fruit are related to its kernel. It has been therapeutic uses for constipation, headache, heart weakness, diarrhea, sedative, amnesia, peptic ulcer, leprosy, polyuria, facial paralysis, Cough, Sexual disability, leprosy, etc. Kaempferol-3-xylosylglucoside and Quercitin are common chemical properties. Almond oil contains the source of vitamin A, B1, B2, B6, E, D, and also contains calcium and magnesium. The preclinical studies mainly depend on flavonoids, phenol, alkaloid, and saponins, tannins. The present review provides comprehensive information of the plant on its Pharmacognostical and Pharmacological profile including its preclinical and clinical studies/ clinical trial and nutritional value in different varieties.
An Overview of Stem Cell Therapy
Authors: D. Sutar Kunal , D. Harshad Rutika , S. Sangar Omkar , C. Patil Aishwarya , A. Payghan Santosh
Published: August 2022

Stem cells are defined as strong clonogenic and regenerative cells and differentiate into multiple cell lines. Stem cells are found in all of us, from the earliest stages of human growth to the end of life. According to the classification of stem cells are divided into 5 types: totipotent, pluripotent, multipotent, oligopotent and unipotent. They are essential for growth, development, maintenance and repair of the brain, bones, muscles, nerves, blood, skin, and other organs. Stem cell therapy continues as a new flexible approach to the treatment of diseases and injuries, with extensive medical benefits. Stock research raises many ethical and scientific questions as well as future challenges. Stem cell therapy, a precursor to a period of cell-based treatment that will one day restore function to those whose lives are now facing the daily challenge, is on its way to recovery. Stem cells have great potential for tissue regeneration and tissue repair but much remains to be learned about their biology, deception and safety before their full therapeutic potential can be discovered. In today’s world, disease control is very exciting and new methods are available to provide quality patient care, on the basis of scientific experiments and practical studies conducted by various institutions and organizations. Mesenchymal stem cells (MSCs) are purchased from most body tissues usually by the placenta and umbilical cord but other sources such as bone marrow found in MSCs are also important as each source will give the cells their own characteristics. They can be used for a variety of heart-related problems, bacterial infections, cirrhosis, liver failure, diabetes, and cancer treatment. A variety of procedures, whether physical or surgical, are available including cell therapy, tissue, osteo-engineering engineering and immunosuppressive tests to treat disease and ensure complete recovery.
Individualizing medical treatment in chronic fatigue syndrome/ myalgic encephalomyelitis: Evidence for effective medications and possible relevance to “Long-Hauler Syndrome” in Covid-19 affected patients
Authors:   Department of Epidemiology (retired), College of Public Health, University of Nebraska Medical Center, Omaha, NE, USA., Levine Paul H , Ajmera Kunal M ,   Department of Hospital Medicine, Calvert Health Medical Center, Prince Frederick, MD, USA., Bjorke Brielle ,   Sierra Internal Medicine, Incline Village, NV, USA., Peterson Daniel ,   Sierra Internal Medicine, Incline Village, NV, USA.
Published: August 2022

Large controlled studies of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) have shown no effective medical treatment for this disorder. There are individual patients, however, with dramatic responses to some medications. We report two patients with clear responses to rintatolimid and galantamine characterized by rapid reduction of symptoms on starting treatment and return of symptoms on withdrawal. As in cancer, CFS/ME is a heterogeneous disorder but unlike most cancers, such as melanoma, breast cancer, and B-cell lymphoma, CFS/ME has no known biological marker that can distinguish between subtypes. We suggest an approach to medical treatment of CFS/ME that could be utilized by primary caregivers that offer the possibility of more rapid and complete recovery from this debilitating disorder. Current studies indicate that prolonged symptomatic recovery from infection with Covid-19 (“long hauler syndrome” or PASC, for post-acute sequelae of Covid-19) represents a severe form of CFS/ME and thus may also be amenable to personalized medicine with specific medications.
RLR-mediated IFN signaling and aberrant activation
Authors:   School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China., Yang Han , Feng Yunran ,   School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China., Feng Chunjing ,   Tianjin University and Health-Biotech United Group, Joint Laboratory of Innovative Drug Development and Translational Medicine, Tianjin University, Tianjin 300072, China., Mu Xin ,   School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Published: August 2022

Interferon (IFN) signaling is important for host cells in defending microorganisms. “Self” and “non-self” recognition is the key step for proper IFN functioning. Pathogen-derived double-stranded RNAs (dsRNAs) are immunogenic to the cytosolic sensor, RIG-I and MDA5. Together known as RIG-I-like receptors (RLRs), they form filament along the length of dsRNA substrate which in turn activate downstream cascades. Despite RLRs themselves and host encoded regulators managing to avoid self-intolerance, extensive studies in recent years uncovered that the boundary of “self” and “non-self” can be vague. Retrotransposon elements embedded in the genome of humans can turn into RLR ligands under certain circumstances, like incorrect RNA metabolism or epigenetic drug treatment, which in turn, lead to IFN signaling activation. The consequences of such activation can be different according to different circumstances. Here, we summarized the biological features of RLR-mediated IFN signaling and discussed aberrant IFN signaling through RLRs, including situations of gene mutations, irradiation, and anti-cancer drug treatment. We speculated that combining current cancer therapy and RLR-mediated IFN signaling activation would bring beneficial effects to cancer treatment.
The role of digitalization in improving the quality of labor resources
Authors: Smagulova N. T. , Baygelova A. N. , Saurukova A. K.
Published: August 2022

The purpose of the research is to identify the role of digitalization in the development of the quality of labor resources based on an analysis of current research on the labor market and the results of the implementation of the Digital Kazakhstan program, as well as to identify areas for improving the quality of training of labor resources through the development of digital skills.   Methodology. In the course of the study, the rationale for the recommendations was carried out using the methods of system analysis, comparison and grouping, general methods of scientifi c knowledge.   The originality / value of the study lies in the fact that without the qualitative development of human resources, the country will not be able to achieve sustainable economic growth. Therefore, more attention should be paid to the use of digital technologies in the formation of the required quality of labor resources. The article provides an analysis of the eff ectiveness of human capital, notes the shortcomings and problems of developing the quality of labor resources at the present time.

   Findings. The authors propose the main directions for improving the quality of labor resources. In particular, the training of specialists, which should be carried out taking into an account of new requirements through the development of digital skills.
Project management in the development of dual learning in the education system of Kazakhstan
Authors: Ibadildin N. A. , Artykbayeva A. Y. , Borashova Sh. M.
Published: August 2022

Purpose of the research. This article is aimed to study the world experience in the application of project management and its approaches in the fi eld of education and in the system of dual education in the Republic of Kazakhstan too. The rapidly developing technologies of the labor market are tightening the requirements for young professionals, so the authors propose to consider new management approaches that will help educational organizations train highly qualifi ed personnel, so necessary for the labor market. The proposed approaches (predictive, adaptive and hybrid) include a set of project management techniques and methodologies that have the potential to solve all necessary organizational issues.   Methodology. The research methodology was implemented through a literature review of scientifi c articles, according to the following keywords: «project management in education», «waterfall approach in education», «Agile in education» and «hybrid approach in education».

   Originality / value of the research. The relevance of the research topic lies in the potential for solving the social problem associated with youth unemployment in the Republic of Kazakhstan among the NEET (Not in Education, Employment, or Training) generation. The originality of the research is confi rmed and substantiated by a small number of scientifi c studies and articles that reveal the use of project management to organize the educational process, especially in the process of organizing a system of dual education in the Republic of Kazakhstan.   Findings. The results of the article are the authors' recommendations on the application of the necessary and appropriate project management approaches at certain stages of the implementation of dual training for its effective development in the country.
Common Pathogens Isolated from Infected Diabetic Foot Ulcers at King Abdulaziz University Hospital, Saudi Arabia: A Retrospective Study
Authors: Alkhatieb Maram , Alrayiqi Rahaf , Alsulami Omar A. , Albassam Ziyad M. , Wali Sahal M. , Alnahdi Haifa
Published: August 2022

Objectives: To determine the common pathogens isolated from DFI to administer appropriate antibiotic treatment, followed by surgical interventions. Methods: A retrospective study was performed on 260 patients who presented with diabetic foot at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, from October 2014 to September 2020. All patients underwent swabs and tissue culture for microbiological evaluation. Patient medical records were reviewed to collect demographic and clinical data, including Glycated Hemoglobin (HgA1C), Diabetes Mellitus (DM) type, duration of diabetes, swab, tissue culture, type of surgery, and type of isolated organism. Results: Escherichia coli was the most common organism isolated from the feet of diabetic patients, followed by Staphylococcus aureus, Klebsiella pneumoniae, Streptococcus agalactiae, and Pseudomonas aeruginosa. Amputations were significantly higher in patients who did not have Staphylococcus aureus or Pseudomonas aeruginosa infection, with no significant relationship between amputation and any other isolated organisms. A significant negative correlation between patient age and HgA1C level was discovered, as well as a significant positive correlation between HgA1C and the number of minor amputations. Patients with major and minor amputations had a significantly higher percentage of non-Multidrug Resistance (MDR), whereas patients with MDR had a significantly higher rate of infection with Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, or Staphylococcus aureus. Conclusion: DM is a metabolic syndrome that affects all the body systems and impacts both morbidity and mortality. The most common organism isolated from the feet of diabetic patients was Escherichia coli, followed by Staphylococcus aureus. Ulcer specimens should be collected for culture and identification of causative organisms. Preventive measures such as good glycemic control, appropriate foot care, targeted antibiotic therapy, and patient education can reduce the incidence of amputation.
International Anthems for LGBTQI+ Community: A Gay Pride– Thematic Analysis
Authors: Mirafuentes Jhon Kevin A.
Published: August 2022

Music as an art form of expression brings the inner side of an artist to the surface, and gives the world an insight of his vision. On the other hand, art is a conscious use of skill and creative imagination especially in the production of aesthetic objects or works. Music is a unique form of art and a lyrical and auditory representation of story. Thus, the study analyzed the patterns or themes of the five selected Gay Pride Playlists or songs such as I’m Coming Out, Born This Way, I Will Survive, True Colors, and Beautiful. The study found out three major themes and patterns that reflected in the five selected Gay Pride Playlists and entailed us to deepen our understanding about sexual orientation, and gender identity and expression. Furthermore, Gay Pride Playlists music, and music as an art, is made for expressing a free spirit that constitutes beauty.
當代金融市場
Authors: 謝劍平 謝劍平
Published: August 2022

國際金融市場正值多事之秋，全球通膨警鐘響起，各國央行為了打擊通膨怪獸，紛紛調升利率，俄烏戰爭開打更加重通膨壓力，新冠肺炎疫情依舊餘波盪漾，全球供應鏈大亂，國際油價持續在高檔震盪，公債殖利率大幅彈升，科技股被重新估值，美元獨強，抗通膨資產成為熱門投資標的。大環境改變也讓金融監理及風險管理愈加重要，另外金融科技、純網銀、ESG、永續金融、開放銀行已成當代金融市場熱門議題，為使讀者掌充分掌握全球金融脈動以及金融產業的創新，本次改版會將上述重大金融史實融入於內文及專欄中。

本書秉持本土化、新觀念的精神，同時搭配「即席思考」、「金融頻道」及「金融新視野」等單元，提供讀者最佳的學習效率。本書探討重心以國內市場為主、國際市場為輔，透過筆者本身在學界多年的教學與研究經驗，以及在實務界任職多年所累積的應用知識，自我期許能讓讀者將理論與實務做更佳的對照與結合。

教學配件：教師教學PowerPoint、教師手冊、題庫

本書搭配：線上題庫、財金新視野影音講座

財金新視野影音講座

引言與介紹

安倍經濟學

金融業打亞洲盃

美QE退場，強勢美元再現

電子支付的潮流

證所稅對台股的影響

是誰在投資殖利率＜0的債券

物價下跌有什麼不好

台灣該加入亞投行嗎

台灣該加入TPP、RCEP嗎

QE一棒接一棒：從美國、日本到歐洲

中國經濟危機

日本負利率政策的影響

2016年世界金融趨勢與展望

負利率政策對全球金融的影響

Fin Tech數位金融的大未來-1

Fin Tech數位金融的大未來-2

從行為投資學探討為何投資人總是賠錢

基金投資的實務分享-1

基金投資的實務分享-2

紅色供應鏈-1

紅色供應鏈-2

英國脫歐對全球經濟的影響

英國脫歐在全球金融市場的後續效應

美國總統大選結果對經濟的影響

美股投資經驗分享

ETF投資經驗分享

中小企業的TRF風暴

從氣候變遷談企業價值永續經營

強勢美元浪潮下的企業避險

艱困地緣政治風險下的台灣企業優勢
經濟學
Authors: 楊雲明 楊雲明
Published: August 2022

本書以淺顯易懂的文句、深入淺出的文字來陳述基礎經濟學的要義，期使初次修習經濟學讀者能夠建立架構；並輔以一些時事問題的探討與分析，讓讀者可以學以致用。本書特色概述如下：

於文中重點標示經濟學名詞、重要結果，以利讀者能輕易地明瞭重點所在。

除更新許多總體經濟資料，並簡要說明景氣對策的綜合分數之計算方式；同時以圖形介紹經濟成長率計算的變革；最後並加上PMI、NMI指標的深入介紹。

在各章內文、章末及智勝文化題庫中，均提供大量練習題（含2021年最新國家考題），對讀者或教師命題都有很大的幫助。

新增許多時事思考，如新冠肺炎下的無薪假、我國平均薪資、群體免疫與外部性、貧窮線、美國通貨膨脹的壓力、通膨螺旋等探討。

教學配件：教學PowerPoint、教師手冊、題庫

本書搭配：線上題庫
América Latina, el Cono Sur y Uruguay: miradas e interpretaciones de los frailes dominicos franceses en los años sesenta
Authors: Monreal Susana
Published: August 2022

Este artículo se refiere a la experiencia de los frailes dominicos franceses de la provincia de Toulouse en Montevideo, y en la región rioplatense, que se inició a mediados del siglo XX. En el estudio de los orígenes, el desarrollo y el agotamiento del proyecto dominico francés en Uruguay, se evidencia la complejidad de esta experiencia humana y religiosa, y la multiplicidad de factores que influyeron en su historia. Esta complejidad fue, por otra parte, incrementada con los profundos cambios que tuvieron lugar en América Latina, en la Iglesia universal y en la vida religiosa, durante estas décadas.

Nos detendremos en lo que llamamos las “visiones dominicanas” en relación a América Latina, el Cono Sur y Uruguay. Por una parte, hubo en algunos frailes una confianza tal vez desmedida en los aportes que un grupo de religiosos franceses podía realizar en América Latina. Por otro lado, se aprecia de qué manera, inevitable por cierto, la vida en Uruguay y los contactos con las culturas iberoamericanas iban transformando la visión y la vida de cada fraile. En concreto, las posiciones fueron variando desde la comodidad y el aprecio de los inicios, hasta posiciones de descontento, de cansancio, de disgusto -ligadas al cuestionamiento de las raíces españoles e italianas de la región-, hasta de desdén, en algún caso, hacia 1970, cuando las ilusiones pastorales se centraron en Perú y México, “una América Latina más auténtica”.
Rezension von: Kohl, Thomas (Hrsg.), Konflikt und Wandel um 1100
Authors: Peltzer Jörg , Kohl Thomas
Published: August 2022

Thomas Kohl (Hg.), Konflikt und Wandel um 1100. Europa im Zeitalter von Feudalgesellschaft und Investiturstreit (Europa im Mittelalter, Bd. 36). Berlin: De Gruyter 2020. 238 S. ISBN 978-3-11- 068064-5. Geb. € 89,95
Rezension von: Kälble, Mathias; Wittmann, Helge (Hrsg.), Reichsstadt als Argument
Authors: Meyer-Schlenkrich Carla , Kälble Mathias , Wittmann Helge
Published: August 2022

Reichsstadt als Argument. 6. Tagung des Mühlhäuser Arbeitskreises für Reichsstadtgeschichte Mühlhausen 12. bis 14. Februar 2018, hg. von Mathias Kälble und Helge Wittmann (Studien zur Reichsstadtgeschichte, Bd. 6). Petersberg: Imhof Verlag 2019. 320 S., 79 Abb. ISBN 978-3-7319-0818-0. € 29,95
Rezension von: Brüser, Joachim, Reichsständische Libertät zwischen kaiserlichem Machtstreben und französischer Hegemonie
Authors: Eberl Immo , Brüser Joachim
Published: August 2022

Joachim Brüser, Reichsständische Libertät zwischen kaiserlichem Machtstreben und französischer Hegemonie. Der Rheinbund von 1658. Münster: Aschendorff Verlag 2020. XI, 448 S., 31 s/w Abb., Kart. ISBN 978-3-402-13406-1. € 62,–
Rezension von: Schapka, Christoph, Die katholischen Kirchen
Authors: Aderbauer Herbert , Schapka Christoph
Published: August 2022

Christoph Schapka (Bearb.), Glocken im Landkreis Tübingen, Teil 2: Die katholischen Kirchen (Tübinger Bausteine zur Landesgeschichte, Bd. 28). Ostfildern: Jan Thorbecke 2019. 414 S., zahlr. Abb. ISBN 978-3-7995-5528-9. € 27,50
Rezension von: Rückert, Peter; Thaller, Anja; Oschema, Klaus (Bearb.), Die Tochter des Papstes: Margarethe von Savoyen
Authors: Auge Oliver , Rückert Peter , Thaller Anja , Oschema Klaus
Published: August 2022

Die Tochter des Papstes: Margarethe von Savoyen / La Figlia del Papa: Margherita di Savoia / La Fille du Pape: Marguerite de Savoie. Begleitbuch und Katalog zur Ausstellung des Landesarchivs Baden-Württemberg, Hauptstaatsarchiv Stuttgart, bearb. von Peter Rückert, Anja Thaller und Klaus Oschema unter Mitarbeit von Julia Bischoff. Stuttgart: Kohlhammer 2020. 248 S., zahlr. farb. Abb., CD und Booklet. ISBN 978-3-17-039341-7. € 22,–
Rezension von: Bihrer, Andreas; Czock, Miriam; Kleine, Uta (Hrsg.), Der Wert des Heiligen
Authors: Kühne Hartmut , Bihrer Andreas , Czock Miriam , Kleine Uta
Published: August 2022

Andreas Bihrer / Miriam Czock / Uta Kleine (Hg.), Der Wert des Heiligen. Spirituelle, materielle und ökonomische Verflechtungen (Beiträge zur Hagiographie, Bd. 23). Stuttgart: Franz Steiner 2020. 234 S. 15 farb. Abb. ISBN 978-3-515-12680-9. € 46,–
Influence of electrospinning parameters on the morphology and performance of filter media
Authors: De Oliveira Alessandro Estarque , Aguiar Mônica Lopes , Guerra Vádila Giovana
Published: August 2022

Nanofibrous filter media used for filtration of nanoparticles dispersed in air can be produced by electrospinning of polymer solutions. However, this process is influenced by many operating variables, including the solution feed conditions. In this work, a 2³ factorial design was used to evaluate the influence of electrospinning variables on the morphology and performance characteristics of filter media composed of polyvinyl alcohol (PVA) nanofibers. The variables considered were needle-collector distance, collector rotation speed, and spinning time. The dependent variables were the median and geometric standard deviation of the fiber diameter distribution, the overall efficiency for collection of NaCl particles (5.94–224.7 nm), and the initial pressure drop. It was found that the needle-collector distance had the most significant influence on the output variables, especially for the median fiber diameter and the initial pressure drop. For these variables, the fitted curves provided coefficient of determination (R²) values of 0.98 and 0.96, respectively.
Sistema público de saúde para adultos e idosos indígenas: relato de experiência sobre o povo Kariri Xocó, estado de Alagoas, Brasil
Authors: Silva Marília Enike Mendonça da , Euzebio Umberto , Faustino Andrea Mathes
Published: August 2022

O presente estudo teve como objetivo descrever aspectos relacionados à estrutura e funcionamento do sistema de saúde do povo Kariri Xocó além de apresentar o perfil da população adulta, idosa e dos profissionais de saúde, com foco nas redes de cuidados tradicionais. Trata-se do relato de experiência de uma acadêmica de Enfermagem da Universidade de Brasília, indígena e pertencente ao povo Kariri Xocó. Em relação à estrutura física é de alvenaria com coberturas de telhas, além de veículos de apoio para o transporte de pacientes e profissionais de saúde. A equipe é constituída por indígenas e não indígenas, totalizando 38 funcionários, dos quais 30 são indígenas. Os adultos representam 52% e os idosos 23% da população. Há déficit quanto ao número de médicos, enfermeiros e de programas estruturados que possam atender de forma específica a comunidade no que tange a Saúde da Mulher, Saúde do Idoso e Saúde Mental. É perceptível a necessidade de um elo maior por parte dos profissionais de saúde que atuam frente a saúde indígena, como forma de inclusão em seus planos de cuidados, para que haja um planejamento de cuidados de acordo com a singularidade e crenças de saúde desta população.
Comparison of interlaminar and transforaminal epidural steroid injection for lumbosacral radiculopathy
Authors: Akkamahadevi P , Srinivas H T , Rashmi H S , Girish B K , Girish Vaishnavi , Reddy Mallireddy Chetan
Published: August 2022

Background: Low back pain due to Intervertebral disc herniation, intervertebral disc degeneration without disc herniation are the most common diagnosis of chronic persistent low back and lower extremity symptoms. Epidural steroid injections (ESI) are one of the most common interventional techniques for managing low back pain with or without lower extremity radiation Aims and objectives: Comparison of the effectiveness of lumbar Interlaminar and Transforaminal epidural steroid injections in managing various types of chronic low back pain. Material and methods: A total of 60 patients with history of lumbosacral radicular pain (≥3 months with VAS score ≥50) and magnetic resonance imaging (MRI) of the lumbar spine showing the exact disc level protrusion, who met the inclusion criteria were selected. With simple purposive sampling techniques, all patients were randomly divided into two groups. Group I Received 4 ml of 0.25% bupivacaine with 8mg dexamethasone through fluoroscopy guided interlaminar epidural route  and Group T Received 2ml of 0.25% bupivacaine with 4mg dexamethasone through transforaminal route. Baseline assessment was completed just before the randomization and then follow up SLRT and VAS score recordings were taken - post 1 week, 1 month and 3 months after the procedure.
Photoacoustic technique for diagnosis of blood clotting
Authors: Majeed Saman Hameed , Hasan Jamal A. , Khalil Eman Ghadhban
Published: August 2022

The photoacoustic technique is considered a scientific renewal in the world of diagnosing blood diseases. The motivation of this study is to get the bio-information about RBCs aggregation by analyzing of the photoacoustic signals represented with microscopic images which linking with artificial intelligence technology. The photoacoustic technique uses the pulsed laser to get the power of photoacoustic signals for recognizing the non-aggregated and aggregated RBCs, as well as estimate the viscosity of blood before and after laser irradiation, that gives an indication to the RBCs aggregation level. On the other hand, microscopic imaging explains the shape, size and amount of RBCs clusters depending on the processing of microscopic images by threshold algorithms.The results of the photoacoustic technique are useful for detection, prediction and identification the potential RBCs clustering and formation of clots in arteries and veins, which occur in several diseases such as infection, inflammation and cardiovascular diseases.
Nocturnal enuresis and related behavioral problems in children
Authors: Kamel Reham Mohamed , Fakher Walaa , Afifi Dina Youssri
Published: August 2022

Objectives: The purpose of this study is to investigate how the prevalence of emotional and behavioural issues in a sample of Egyptian youngsters relates to nocturnal enuresis. Methods:The Center of Social and Preventive Medicine at Cairo University's Enuresis specialised outpatient clinic served as the source of 200 of the youngsters for this cross-sectional study. Children in the NE varied in age from 5 to 14 years; their mean age was 8.6 2.3 years. There were just as many boys and girls among the children. Strength and Difficulties Questionnaire was used to evaluate behavioural problems (SDQ). Results: When it comes to emotional scale, 37% of participants fall into the abnormal category, and 41% were labelled abnormal when it comes to hyperactivity and inattention. Although 34% of the individuals reported aberrant scores for all issues, boy's average scores were significantly higher. the existence of behavioural and emotional issues in a sample Females scored lower on the hyperactivity-inattention scale than males (6.5 vs. 4.5; p-value 0.001) In summary, NE is linked to an increased incidence of behavioural issues that point to both internalising and externalising symptoms.
effectiveness of the main commodity buffalo cow program in Rokan Hilir Regency
Authors: Putra Dedy Kurnia , Salioso Herdi , Febrianto Surizki , Rahman Firdaus A , Rosmayani Rosmayani
Published: August 2022

This study aims to see the effectiveness of the main commodity Buffalo Cow program in Rokan Hilir Regency. In carrying out the program, of course, the Regional Government of Rokan Hilir Regency in this case is at the Food and Agriculture Security Agency wanting to achieve or meet the targets in the Program so that the program is effectively implemented in Rokan Hilir Regency and of course increases the population, especially cow and buffalo. This research uses a qualitative research method with a descriptive research type. The main informants in this study were Supervisor, Recorder, Inseminator, Botanical Inspection Officer, Birth Officer and Breeder. Sample selection is made by (purposive sampling). The result of this article is Production; this program's results can increase the cattle population more quickly and produce good quality offspring. Efficiency; this commander program is implemented based on technical instructions and decrees but has no optimal operational support from the Government of Rokan Hilir Regency; officers or human resources that are still limited by long distances are an obstacle in implementing the commander program
Understanding meaning expression parable by an Indian students
Authors: Mafuzin Tunku Aidayuhanna Raja , Wan Mohammad Wan Muna Ruzanna , Mahamod Zamri
Published: August 2022

This study aims to explore the understanding of meaning in parables by Indian students. The adaptation and modification of Roland Barthes’s Semiotic Theory and Lev Vygotsky’s Theory of Social Constructivism were used as the basis of the study. A qualitative design was used in this study. The study was conducted in a regular daily secondary school in Selangor involving five Indian students, where Malay is the second language. Parables are one of the types of proverbs contained in the Form Two Malay Language Curriculum and Assessment Standard Document. Cermin Minda Instrument: Parables are used to test students' levels of understanding of the meaning of parables. The results of the analysis found that the study participants could name visual objects denotatively but failed to associate the parable with the visual object. Study participants also failed to express the meaning of proverbs accurately based on their concepts. Overall, students have not yet mastered the understanding of the meaning of parables because they are unable to reach the level of expressing implicit understanding in producing new cognitive. The implication is that students need to be given comprehensive exposure to parable expressions as well as denotative and connotative meanings to produce new cognitive.
Homologous ELISA for detection of 17α-methyltestosterone in serum
Authors: Verma Divya , Shrivastav T. G. , Thakur Sonu Chand
Published: August 2022

17 α Methyl testosterone is a synthetic steroid hormone having androgenic properties. It is used in aquaculture, medical treatments, in sports as doping drugs, in improving food efficacy but its residue in meat and their products can cause risk to the human, animals and environment. In this article, we have focused on developing homologous ELISA using 17α Methyl testosterone-3-Carboxymethyloxime-Bovine serum albumin antiserum and 17α Methyl testosterone-3-Carboxymethyloxime-Horseradish peroxidase enzyme conjugate. Immunogen and enzyme conjugate both were prepared by N-hydroxysuccinimide mediated carbodiimide reaction method. The sensitivity, affinity and ED50 of the assay were found to be 0.11 ng/ml, 0.02x10-8 L/mol and 5.78 ng/ml respectively. The cross reactivity for this assay combination was seen with eight steroids out of 59 structurally related steroids. The assay was then studied for analytical variables like recovery (94.8%-111.6%), precision (Inter and Intra-assay coefficient of variation less than 10%), correlation (R2= 0.96) by comparing with commercially available kit and further validated by measuring levels of 17α methyltestosterone in rat serum after injecting rats intramuscularly.
Determine the correlation between malaria severity assessment score and duration of hospital stay in malaria patients at tertiary care centre
Authors: Nawaz Alam , Solati Rahul Reddy , Bhat Ajay Nagesh , Nayak Arjun
Published: August 2022

INTRODUCTION: Malaria is the most important tropical disease accounts for mortality with estimates of over million deaths around the world making an impact to society. Malaria can lead to various organ system dysfunction and cause mortality and morbidity of the patient. Purpose of this study is to determine correlation between malaria severity assessment score and duration of hospital stay among the patients of malaria at tertiary care centre. METHODS: A cross-sectional study involving patients diagnosed with malaria as per WHO guidelines across a study period of 18 months was conducted from 2019- 2021. organ dysfunction was taken into consideration and used for assessment of malaria severity score. RESULTS: Among 82 positive cases of malaria, various parameters were taken into consideration for the assessment of score. among them neurological and hepatic parameters are least significant and contributes for less than 1 percent of cases and also severity. Renal parameters contribute for about 50 percent of mild cases and 2 percent of moderate cases among both males and females. Respiratory parameters show 40 percent of mild cases and 1.2 percent of moderate cases.
Significance of mindfulness, Al-Quran recital and prayer factors in coping with COVID 19 symptoms
Authors: Malek Jalaluddin Abdul , Hasan Ahmad Zaki , Rahman Ab Z. , Khairuddin Wan Haslan , Muhamad Siti Norlina , Said Suzana Muhamad , Tahir Zurinah
Published: August 2022

Mindfulness in Islam is akin to muqarabah, which refers to an individual’s practices in a situation where he has completely surrendered himself to Allah SWT, which is reflected in the calmness, peacefulness and awareness evident in him after doing so. According to Islam, prayers (solat) affect a person’s mental health. The word “solat” originates from Arabic and it is the derivative noun (masdar) from the verbs (fi’li) solla, yusolli, solatan, which means doa (supplication prayers), istighfar, al-maghfirah, al-rahmah, al-Islam, al-din. Al-Quran contains various elements needed by humankind, such as religious, social, economic, health, medical, scientific, political and other aspects, as a guide for achieving prosperity in this life and the afterlife, reciting the al-Quran daily showers a person with continuous serenity, which is a very effective therapy for a person facing pressures in life. recital Quran has a unique power in changing an individual’s inappropriate behaviour to appropriate behaviour. Al-Quran also provides all the internal and external needs required by a person to face the various challenges, reciting the al-quran is not only advantageous to a person but listening to recitals can also provide serenity and blessings from Allah swt.
Evaluating Geochemical Discriminants in Archean Gold Deposits: A Superior Province Perspective with an Emphasis on the Abitibi Greenstone Belt
Authors: Hastie E.C.G. , Kontak D. J. , Lafrance B. , Petrus J. A. , Sharpe R. , Fayek M.
Published: August 2022

Discriminating Archean Au deposit types and related ore-forming processes is challenging but paramount for increasing Au exploration success. This study tests the validity of applying geochemical data generated from conventional bulk versus modern in situ methods as discriminants for classifying Au deposits in the Archean Swayze greenstone belt with further comparison to other deposits in the contiguous Abitibi greenstone belt and Red Lake area (Superior Province, Canada). The study used five well-characterized Au settings, based on new mapping, as a basis for evaluating in situ (δ18Oquartz, δ33, 34Ssulfide, laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) analysis of pyrite, electron microprobe analysis of gold), and whole-rock geochemical datasets to resolve whether intrusion-related Au deposits can be discriminated from orogenic-type Au deposits. Results show that the in situ methods provide insight into processes related to Au mineralization, both primary and subsequent remobilization and upgrading, and define elemental and isotopic correlations that cannot be resolved using conventional bulk methods. For example, when comparing the whole-rock to laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) trace metal data, only Ag, Te, and Hg show a consistent positive correlation with Au across deposit types in both data sets. Furthermore, the wholerock datasets combined with in situ isotopic analysis suggest the Archean sanukitoid-associated Au deposits represent a distinct group of intrusion-related deposits with mineralization characterized by low δ34Spyrite (<–5 to –25‰), inferred high fO2, an Hg-Te signature, and hosted in intrusions of <2690 Ma that predate shearing. The data and interpretations presented herein provide a baseline that can be widely utilized in future studies of Au deposits.
Acute Coronary Syndrome with ST Segment Elevation: New Electrocardiographic Pattern
Authors: Abreo Diego
Published: August 2022

A 58-year-old man with a history of hypertension and diabetes, presented to the emergency department (ED) after 2 hours of oppressive, severe chest pain radiating to the left arm and associated with dyspnea. Upon arrival he was stable, an ECG was performed that demonstrated an isolated elevation of the J point in DIII, with depression of the J point in DI, DII, AVL, V4 to V6, with isoelectric ST segment in AVF. Troponine was not expected because an ST equivalent pattern was suspected. Should the patient be treated for an acute coronary syndrome with elevation of the ST or non-ST elevation based on the ECG findings?
An Examination of Common Errors in Essays Written By Secondary School Students in Malawi: Some Implications for Teaching
Authors:   Mzuzu University, Kwachakale Kavute Christopher , Chimangeni Chaliwa Hara Agness ,   Mzuzu University
Published: August 2022

This study aimed at analysing errors in essays written by Malawian students who were learning English as a Second Language (ESL). Its specific focus was three-fold: to analyse errors using Corder’s (1974) five-stage approach to Error Analysis, to assess sources of the errors and to identify measures that could be applied to help students attain proficiency in English. The study utilised qualitative and quantitative designs. The participants in this study were students and teachers. The former were required to write essays which were analysed using Corder’s (1974) five-stage approach to Error Analysis while the latter were interviewed to establish sources of errors and ways to overcome them. The study has revealed that the following were the most frequent errors: tense, spelling, subject-verb agreement, articles, nouns, capitalisation and fragment. The study has further revealed that inter- lingual and intra-lingual interferences were the main sources of errors. The study has further demonstrated that other factors such as a lapse in reading culture, carelessness and social media’s writing style influence students’ errors. This study has shown that Error Analysis is helpful to teachers because it enables them to identify specific and common problems. Teachers can, therefore, focus more attention on the identified problems. The findings have pedagogical implications for ESL teachers because they would employ appropriate pedagogy to minimise students’ errors in the area of grammar and sentence structures. The findings also have practical implications in the sense that some platforms could be organised in order to grill teachers on how to improve their content and pedagogical skills in ESL writing. Teachers could also use these platforms to share their experiences with fellow teachers and map the way forward to improve their instruction skills.
Application of Political Satire in Mission to Kala and Devil on The Cross
Authors:   University of Zambia, Mbewe Ian
Published: August 2022

The study attempted to demonstrate how political satire is applied in a pre-independence African fiction Mission to Kala and a post- independence African fiction Devil on the Cross. Satire, mild or bitter, has a history of being used to expose the negative socio-economic and political realities perpetrated by both the sympathisers of colonialism and later the agents of neo-colonialism in the post-independence phase. The study employed the Marxist literary theory and Literary Onomastics through stylistic analysis and demonstrated how satire exposed the evils and how a ‘training camp’ in the colonial era was transformed into a ‘jungle’ in post-independent Africa. Character types in both periods exhibited parasitic traits such as greed, selfishness, narrow appetites and sadistic violence leading to exploitation and oppression. This historical transition was delineated on the basis of the colonised African elite and subordinates as the direct off-shoot of the African bourgeoisie groups, which created a symbolic connection between the two periods of time in the African context. The findings indicated that both texts maintained the Marxist outlook, employed ironic juxtaposition to satirise capitalism, each satirist employed a different style and Beti had the colonised African elite and subordinates as his targets of satire as opposed to Ngugi’s comprador politicians, comprador and national bourgeoisie. The masses were not spared of criticism.
Spatial Analysis of Ecological Corridors in Giant Panda National Park Based on GIS
Authors: Yang Mengting
Published: August 2022

As one of the national park pilot areas, the main goal of The Giant Panda National Park is to protect the authenticity and integrity of the natural ecosystem which is centered on the giant panda. Because of the large scope of national parks, it is necessary to plan ecological corridors reasonably to protect the integrity and authenticity of the ecological environment. Based on the GIS system, this paper analyzes the ecological environment of giant pandas living in The Giant Panda National Park and processes the information from the spatial scale. Using the cost-distance analysis tool to analyze the corridors with the method of least cost, 12 ecological corridors within the research scope were accumulated. An ecological corridor model planning and construction with the purpose of the giant pandas have been proposed, and the writer also discusses how to promote the construction of ecological corridors when developing Ecotourism at the same time in the national park. Then point out the management of ecological corridors of The Giant Panda National Park.
Analysis of Enterprise Performance Management from The Perspective of Game Theory
Authors: Li Linling , Li Kang , Yang Junze , Zhao Wenzhuang , Li Shihao
Published: August 2022

Performance management has always been one of the most important problems in human resource management. This paper mainly uses the classic example of "Prisoner's Dilemma" in game theory and the theory of dynamic game, through analyzing the process of horizontal game and vertical game in enterprise development, reveals the direct influence of game behavior in enterprise development, and aims at the adverse influence caused by it in enterprise development. This paper gives a set of suggestions on establishing and improving the game theory criterion in enterprise performance management, and uses the constraint system and game theory criterion to help the company's leadership and management team form an effective equilibrium solution to ensure the completion of the performance management goal, and then achieve the company's strategic goal.
The Impact of Epidemic on High School Students' Consumption Behavior
Authors: Ji Wenhan , Li Xinyi
Published: August 2022

COVID-19 is affecting people's lives from 2020 to today. Among all the influences, the influence on people's consumption behavior is particularly prominent. In this paper, the impact of the epidemic on the consumption behavior of high school students in Beijing is studied. With the progress of The Times and the development of science and technology, the consumption behavior of senior high school students becomes more and more, no matter online consumption or offline entity shop. Therefore, studying the impact of the epidemic on the consumption behavior of high school students can also extend the impact of the epidemic on the society and even the macro economy of the country.
The Influence of Byzantine Law in East Central Europe
Authors: Šarkić Srđan
Published: August 2022

The first part of the chapter is dedicated to the sources of Byzantine law, that is, secular and ecclesiastical. The most important secular laws are: 1) the Farmer’s Law from the 7 th or 8 th century, concerning the peasantry and the villages; 2) the Ecloga (726 or 741) issued by Emperor Leo III and his son Constantine V; 3) Legislation of the Macedonian dynasty or the so-called ‘Re-cleansing of the Ancient Laws,’ including Epanagoge, Procheiron, Basilika, and the Novels of Leo VI; and 4) Hexabiblos (Six Books), which is a private codification compiled by Constantine Harmenopoulos, judge of Thessalonica. The most important ecclesiastical laws are: 1) Synopsis Canonum, a summary of abridged canons arranged in alphabetical or chronological order; 2) ‘Systematic collections’, Synagoge, and Syntagma Canonum, organized by topic; 3) Nomokanons, compilations of secular laws and canons; and 4) Matheas Blastares’ Syntagma and Constantine Harmenopoulos’ The Epitome of the Holy and Divine Canons. The second part of the text treats the reception of Byzantine law in Slavonic countries: 1) the Slavonic Ecloga and the oldest preserved Slavonic legal text Zakon Sudnyj Ljudem (Law for Judging the People or Court Law for the People); 2) the Slavonic Nomokanons or Kormchaia kniga; and 3) the Stefan Dušan’s codification, consisting of the Serbian translation of Matheas Blastares’ Syntagma, Justinian’s Law (a short compilation of 33 articles regulating agrarian relations), and Dušan’s law code in the narrow sense. The third part of the chapter refers to the reception of Byzantine law in the Danubian principalities (Wallachia and Moldavia) transmitted through the Serbs and the Bulgars and their processed Slavic legal works received through Byzantine officials and through the church. The last part of the text is dedicated to the Byzantine public law’s ideas in East Central Europe. The most important and common ideas espoused in the work are: 1) the Roman, Byzantine, and Slavonic concepts of law, 2) the idea of Rome and a hierarchical world order, 3) the emperor’s task, and 4) concordance or ‘symphonia’ between the church and the state.
Regulation of Public Finances in Slovenia in Light of Financial Constitutionality
Authors: Bohinc Rado
Published: August 2022

The purpose and the objectives of this chapter is to present briefly some of the legal theory of finance, followed by information on recent developments and current challenges in financial law and to present relevant financial institutions in the Republic of Slovenia (RS). This chapter is comprised of four subchapters. The first subchapter deals with the legal theory of finance, presenting theoretical views on public finance and financial law, about legal nature of the public budget, further on the legal theory of finance and on theoretical views related to constitutional provisions and the performance of the economy. The second subchapter deals with the public finances developments and trends in Slovenia, followed by brief description of fiscal system in Slovenia and some facts on management of public property. The third subchapter presents financial institutions in Slovenia. Ministry of finance, constitutional (Court of Audit and the Central Bank) and other financial institutions are briefly presented as follows: the Financial Administration, Agency for public oversight of auditing, Securities market agency, Ljubljana stock exchange, Slovenian sovereign holding and public institutions and public funds in general. The fourth subchapter presents current and planned regulatory challenges; it presents resilience and recovery measures, current measures to mitigate the effects of the COVID-19 epidemic and information on some of the planned future legislative initiatives.