bluuebunny/crossref_metadata_2025 huggingface dataset:
Predicting the development of cardiac arrhythmias and cardiac conduction disorders in patients
Authors: Nicoulina S. Yu , Chernova A. A , Tretyakova S. S , Plita E. V
Published: February 2021

The article is devoted to descriftion of the new method for diagnostics and predicting of the development of risk for development of cardiac arrhythmias and cardiac conduction disorders in patients by using of the computer system. For oftimization of the diagnostic and prevention of these pathologies in different health facilities (outpatient clinics, in-patient clinics)was developed a technology for the estimation of genetic risk and predicting in families by analysis of clinical, instrumental and genetic data. The process is automated by using the analytical software complex (computer system). The basis for the technology is the results of our multiyear researches to identify associations between the genetic polymorphisms and different cardiac conduction disorders. The article presents the possibilities of using the developed technology in clinical practice, the basic principles of work with the computer system.
A rare case of transthyretine amyloidosis with heart damage and widespread systemic manifestations
Authors: Boldueva S. A , Samokhvalova M. V , Khomulo A. D , Zaitsev V. V , Marinin V. A , Vinnichuk S. A
Published: February 2021

The article describes the rare clinical case of transthyretine amyloidosis in young patient, manifested by heart rhythm disturbances and biventricular heart failure.
The influence of trimetazidine on recovery of functional and mental capacity in patients undergoing II stage of cardiac rehabilitation after coronary artery bypass grafting
Authors: Alexandrov P. V , Perepech N. B
Published: February 2021

Object - to evaluate effect of trimetazidine on functional and mental capacity in patients undergoing II stage of cardiac rehabilitation after coronary artery bypass grafting. Material and methods. 125 patients referred for cardiac rehabilitation after coronary artery bypass grafting were divided in two groups. Patients of control group received pharmacotherapy according to current guidelines on secondary prevention of coronary heart disease. Active treatment group patients (n=30) received trimetazidine 35 mg bis in day additionally. Functional capacity was assessed by six-minute walk test. Mental capacity was evaluated by psychomotor performance express-test of M.P.Moroz. Results. Majority of patients had reduced functional and mental capacity on admission. Performing of cardiac rehabilitation program comes with increase in six-minute walk test distance and psychomotor performance test scores in both groups. An increase in six-minute walk test distance and psychomotor performance test scores in active treatment group was significantly greater than in control group. Conclusion. Trimetazidine therapy improves both functional and mental capacity in patients undergoing II stage of cardiac rehabilitation after coronary artery bypass grafting.
The effects of climate in patients with arterial hypertension, including in combination with chronic obstructive pulmonary disease and/or bronchial asthma
Authors: Chazova I E , Ratova L G , Dolgusheva Y A , Nazarov B M , Agapova O Y , Sivakova O A , Galitsin P V , Rvacheva A V , Kuznetsova T V , Beilina V B , Tkachev G A , Kaznacheeva E I , Zykov K A
Published: February 2021

Objective: to examine the characteristics of the regulation mechanisms of the cardiovascular system under the influence of climatic factors of the patients with arterial hypertension (AH) without comorbidity compared to the patients with AH and associated pathology (chronic obstructive pulmonary disease and/or bronchial asthma).Conclusion: during the spring of 2012 – winter of 2013 abnormal summer heat and abnormally low temperatures in winter in the central region of Russian Federation were not observed. Against this background, patients with AH, including with BOD did not have any significant changes of BP and HR in summer compared to those in spring. The increase of the daily average temperature in summer was followed by a significant increase of ventricular extrasystoles. In assessing of the endothelial dysfunction it was proved that it showed a significant deterioration due to hot weather. The best estimation of general health state was noted in winter period according to the VAS. The spirometric parameters of the patients with AH and BOD were significantly better at this time of the year.
Place of arterial hypertension in brain lesion development - from minor cognitive disorders to dementia
Authors: Shishkova V N
Published: February 2021

He problem of cognitive impairment in patients with somatic diseases today occupies a leading position, as it represents one of the most widespread manifestations of organic brain damage. The role of arterial hypertension(AH) in the formation of cognitive impairment (CI) has been shown in large epidemiological studies. CI detected in 73% of patients of both middle and senior age with hypertension duration of more than 5 years. Early detection of potentially treatable cognitive disorders is one of the most important tasks of the modern practitioner, cardiologist, endocrinologist, family doctor, as the patients in the early stages of CI constitute the majority of people seeking help. In today's world, primary care physicians' actions are often crucial in the prediction of dementia, since the detection of early forms of non-dementia CI and timely and adequate treatment of cardiovascular disease, especially hypertension, is often enough for the severity of the CI patients was significantly decreased, and dementia never came.
The functional state of microcirculatory vessels in patients with arterial hypertension I-II degree with different degrees of cardiovascular risk
Authors: Mordvinova E V , Oschepkova E V , Fedorovich A A , Rogoza A N
Published: February 2021

Aim: to evaluate the main parameters of the microcirculatory blood flow and to determine its reserve capacity in patients with arterial hypertension (AH) and different degrees of cardiovascular risk (CVR).Subjects and methods. We examined 64 subjects aged 47-58 years, of which 27 were healthy volunteers and 37 patients with 1st and 2nd degree arterial hypertension, with medium, high and very high CVR (the antihypertensive therapy was cancelled for 2 weeks before the study). In all subjects laser Doppler flowmetry (LDF) with studing initial perfusion parameters, 2 constrictor and 3 dilatator tests waky perfomed. To assess the status of the tone-shaping «active» and «passive» parts of microcirculatory modulation, analysis of the amplitude and frequency spectrum of LDF- grams was carried out.Results. A significant increase in the rate of «base perfusion» in all hypertensive groups compared with the control group was found. The amplitude of respiratory oscillations was one-third higher in high and very high CVR groups in comparison with the control, the amplitude of the myogenic and neurogenic oscillations were maximal and reached significant values in very high CVR group. A reduction in constrictor response in hypertensive patients with middle and high CVR and its increase in the very high CVR group was shown during constrictor functional tests. The power of perfusion increase was reduced in response to all kinds of dilatator stimulus in hypertensive patients group.Conclusion. The findings indicate a progressive increase in the level of «base perfusion», worsening of venous congestion symptoms in hypertensive patients with the progression in CVR severity. High and very high CVR patients showed a reduction in myogenic tone of microvessels when compared with those with normotension. Dilatator functional tests showed a tendency to lower capillary blood flow reserve in hypertensive patients compared with the control group.
Role of the Pulse Oximetry in the cardiologist's practice‌‌
Authors: Aksenova A V , Yelfimova Ye M , Galitsin P V , Goriyeva Sh B , Bugayev T D , Mikhailova O O , Litvin A Yu , Rogoza A N , Chazova I Ye
Published: February 2021

The study had two phases: the first phase of exploring the possibility of a computer pulse oximetry as a screening method for the diagnosis of respiratory disorders during sleep in patients with cardiac profile in steady-state conditions, the second - a screening study of prevalence of obstructive sleep apnea in the same category of patients. In a comparative study of two methods: cardiorespiratory monitoring (4 channels, held monitoring device «Kardiotekhnika-07», «Incart», Russian, and computer pulse oximetry device PulseOx 7500, SPO medical, Israel) included 70 patients (70% men and 30% of women), mean age 55,5±11,2 years. The sensitivity of the computed pulse oximetry in detecting disorders of breathing during sleep (number of episodes of more than 5 per hour, reducing the saturation of more than 3%) was 94,4%; specificity - 79,2%; positive predictive value - 91,1%; negative - 86,4%; accuracy - 87,7%. In a screening study included every fifth patient entering the Russian Cardiology Research and Production Complex MH of the Russian Federation. Patients of the departments of cardiovascular surgery, emergency cardiology department of chronic heart failure, patients with respiratory diseases COPD, asthma were excluded. Statistical analysis included 206 patients. Median age was 68,4±13,7 years, BMI - 32,9±5,5 kg/m2, 43,6% of men and 56,3% of women. From 5 to 15 events per hour was observed in 31,1% of patients, from 15 to 30 events/h - 31,1% and more than 30 events per hour - 23,9%. Thus, respiratory disorders of varying severity were in 77,4% randomly sampled in the study patients.
The state of the vascular wall in adult population of Tomsk in the framework of the project ESSAY RF
Authors: Rogoza A N , Kaveshnikov V S , Trubacheva I A , Serebriakova V N , Zairova A R , Zhernakova Yu V , Oshepkova Ye V , Karpov R S , Chazova I Ye
Published: February 2021

The article presents the results of study of arterial stiffness, ankle-brachial index and pulse pressure in adult population of Tomsk in the framework of the project ESSAY RF (Epidemiology of Cardiovascular diseases in the Regions of the Russian Federation). 1379 men and women of 24-64 y.o. were studied by using volumetric sphygmography (VaSera VS-1500, Fukuda Denshi, Japan).The optimal values of CAVI (cardio-ankle vascular index), as a marker of arterial stiffness, were considered in group of relatively healthy persons in russian population. CAVI values in whole studied population were analyzed in comparison with data of other researchers and in association with CVD and CVD risk factors.
Longitudinal deformation of the left ventricle and the left atrium in workers of railway transport with arterial hypertension
Authors: Marsalskaya O A , Nikiforov V S
Published: February 2021

The research objective was in studying and evaluating the indicators of longitudinal deformation of the left ventricle and the left atrium in persons with arterial hypertension (AH), and also in persons with risk factors, but without AH, workers of railway transport.Materials and methods. The workers of railway transport under research are: 45 patients with AH, 35 people with risk factors, but without AH and 20 healthy volunteers. All the people under research were exposed the transthoracal echocardiography on ultrasonic Philips iE 33 system (Holland) including two-dimensional impulsive wave tissue Doppler echocardiography.Results. The decrease of a systolic velocity of a fibrous ring of the mitral valve in the region of septal and lateral segments in both groups is observed in comparison with the control. In studied groups deterioration of a diastolic function and significant decline of indicators of global longitudinal deformation of a left ventricle and the left atrium in comparison to healthy people are also registered. Depression of segmental deformation of a left ventricle in both groups has a chaotic character. The more the index of mass of a myocardium of a left ventricle, the lower indicators of global deformation are; the more the index of volume of the left atrium, the lower indicators of deformation of the left atrium are.Conclusion. Depression of diastolic and segmental systolic functions of a left ventricle of workers of railway transport is registered both with AH and without AH, but with risk factors that are reflected in indicators of longitudinal deformation of a left ventricle and a left atrium.
Prognostic factors of cardiovascular complications during the heatwave of 2010 (cohort observational study)
Authors: Smirnova M D , Fofanova T V , Ageev F T
Published: February 2021

Aim of the study was to identify prognostic factors of hypertensive crisis during the heatwave of 2010. Materials and methods: observational cohort study involving 754 patients with moderate/low, high/very high risk and patients with CAD. Medical documentation and questionnaires was used. Selectively (344 pers.) were done sphygmography Visits were conducted in april - may and september - october 2010. Results: The frequency of cardiovascular complications increased during heat waves than in the september - october 2010. There were more hypertensive crises, unscheduled visits to the doctor and arrhythmia during the heat wave than after the heat. CAD [OR 1.8 (1.1-2.8)], a history of stroke [OR 3,4 (1.0-11.4)], intake of nitrates [OR 3.1 (1.1-9.1)] and discontinuation of antihypertensive medications [OR 2.7 (1.4-5.1)] proved to be predictors of hypertensive crisis during heat wave. Independent predictors had a history of stroke [OR 5.3 (1.1-25.1)] and the discontinuation of antihypertensive medications [OR 2.5 (1.2-4.9)]. Conclusion: CAD, intake of nitrates, history of stroke and discontinuation of antihypertensive medications proved to be predictors of hypertensive crisis during heat wave. Independent predictors had a history of stroke and the discontinuation of antihypertensive medications.
Chronotherapy’s opportunities of a fixed combination of perindopril 10 mg/indapamide 2.5 mg in patients with a lack of night reduction in blood pressure
Authors: Aksenova A V , Elfimova E M , Litvin A Yu , Chazova I E
Published: February 2021

Currently, adequate reduction of blood pressure (BP) during the night in patients with arterial hypertension remains important problem. To study chronotherapy’s opportunities to achieve better BP control by a single dose of antihypertensive drugs while maintaining high compliance. Aim. To evaluate the efficacy, tolerability, safety of various prescription regimes of fixed combination: perindopril 10 mg and indapamide 2.5 mg in patients with insufficient degree of BP reduction at night. Design and methods. The study included 30 patients (20 men and 10 women, 56±9.3 years, body mass index 30.5±5.3 kg/m2, the duration of arterial hypertension - 7.1±5.8 years), on ineffective dual antihypertensive therapy (BP>140/90 mm Hg). Initially, ambulatory BP monitoring (ABPM) and blood tests were performed. Then, previous therapy was terminated and fixed combination of perindopril 10 mg/indapamide 2.5 mg (Noliprel A Bi-forte) was administered. Patients were randomized into two groups: morning and evening regimens of therapy. After 8 weeks of treatment ABPM and blood tests were repeated. Statistical analysis was done after further separation of patients into groups with sufficient (dippers) and insufficient (non-dippers) degree of BP reduction at night. Results. In the group of "non-dippers" average ambulatory systolic BP (SBP) during wakefulness declined from 149.4±11.7 mm Hg to 129.8±10.6 mmHg (p
Advantages azilsartan medoxomil in patients with arterial hypertension: how to make a choice and to optimize antihypertensive therapy?
Authors: Martynyuk T V , Chazova I E
Published: February 2021

Azilsartan medoxomil is a drug from class of angiotensin II receptor antagonist (sartans), have a antihypertensive effect and excellent tolerability profile. In comparison with other drugs (candesartan, olmesartan, ramipril, chlorthalidone, valsartan) according to comparative studies and meta-analyses azilsartan medoxomil demonstrated high antihypertensive efficacy, in terms of 24-hour BP control, which allows to recommend its purpose in patients of hypertension 1-2 degrees. This is due to the ability of the drug not only safely reduce AD during day and night hours, but also to normalize the circadian profile. Pleiotropic effects of azilsartan medoxomil in the form of increased sensitivity of receptors to insulin, a positive effect on glucose metabolism, improved endothelial function allow us to consider its purpose in patients with carbohydrate metabolism disorders, overweight, obesity, and metabolic syndrome. The drug is indicated for as patients who have not previously received antihypertensive therapy and if previous treatment with other RAAS blockers did not lead to reliable achievement of target BP levels. High efficiency and safety of azilsartan medoxomil can provide better patient adherence to long term therapy and achieve optimal results of therapy.
A Study on Different Hurdle Factors of Nano Metal Vitamin Complex for the Prevention of Microbial Spoilage in Seafood
Authors: Haris V T  , Gobianand K
Published: February 2021

Hurdles that have a positive effect by inhibiting microorganisms may have a negative one on other parameters such as nutritional properties or sensory quality, depending on their intensity. In order to lower the preservative level, the hurdle technology concept has been developed, consisting in using combined hurdles to establish an additive antimicrobial effect, and even sometimes a synergetic one, thus improving the safety and the sensory quality of food. The antibacterial and anti-oxidant potential of copper oxide nano particles coupled with vitamin-E (CuONPs+VE) was investigated by applying the novel hurdle factors against seafood pathogens and by studying the cell viability using MTT assays. The hurdle method is proposed to explain the significance of combined use of different preservation factors as synergistic effects instead of using a large-intensity preservation factor. Effect of CuONPs+VE and chilling temperatures (-18°C and +4°C); and Effect of CuONPs+VE and brine salts at various concentrations (5%, 10%,) were evaluated. CuONPs+VE with different chilling temperatures and brine salt concentration showed significant results on compared to control temperatures. Thus CuONPs+VE due to their bacteriostatic activity can be efficiently used in hurdle technology which reduces the food spoiling organisms. Thus CuONPs+VE in combined with hurdle technology can be used as alternatives for chemical preservatives in preservation techniques.
THE CONSTRUCTION OF A PERSONAL BRAND AS PART OF PROFESSIONAL IDENTITY FASHION- AND BEAUTY BLOGGERS
Authors: Бурлаченко Лариса Сергеевна
Published: February 2021

Рассматриваются понятия личного бренда, профессиональной идентичности, самоконструирования и трансляции образа себя в социальной сети. Проведён сравнительный анализ самопрезентации и построения блогерами личного бренда за рубежом и в России. Использован метод контент-анализа самопрезентации личного бренда бьюти- и фэшн-блогеров социальной сети Instagrаm, методологическая основа теории интеракционизма И. Гоффмана [2]. Было выявлено: для конструирования и укрепления образа «я» в представление «других» блогеры используют визуальные средства (фото/видео), а для расширения социальных взаимодействий блогеры используют технические возможности: Instagram-хэштеги, отметки пользователей и брендов. Исследование направлено на изучение личного бренда, профессиональной идентичности блогеров как новой профессиональной группы современного общества, а также позволяет сравнить способы самопрезентации личных брендов зарубежных и российских блогеров.

The article discusses the concepts of personal brand, professional identity, self-construction and translation of self-image in a social network. The aim of the study is a comparative analysis of self-presentation and the creation by bloggers of a personal brand abroad and in Russia. The method of content analysis of self-presentation of the personal brand of beauty and fashion bloggers of the social network Instagram was used, the methodological basis of I. Hoffman's theory of interactionism [2]. As a result, it was revealed that bloggers use visual means (photos / videos) to design and strengthen the image of «I» in the representation of «others», and to expand social interactions, they use the technical capabilities of Instagram - hashtags, user and brand marks. This study fills the gaps in the study of personal brand, professional identity of bloggers as a new professional group of modern society, and also allows to compare the ways of personal presentation of personal brand of foreign and Russian bloggers.
PSYCHOLOGICAL PREDICTORS OF FORMATION OF A CONCEPTUAL MODEL OF THE CONTROL OBJECT IN ELECTRICIANS OF ELECTRIC NETWORKS
Authors: Епатко Сергей Сергеевич
Published: February 2021

Проведено исследование психологических предикторов сформированности концептуальной модели объекта управления ремонтно-эксплуатационного персонала на базе двух электросетевых компаний: акционерного общества «ЛОЭСК - Электрические сети Санкт-Петербурга и Ленинградской области» (АО «ЛОЭСК») и открытого акционерного общества «Сетевая компания» Республики Татарстан (ОАО «Сетевая компания»). Проведен факторный анализ и выявлен фактор, влияющий на состав концептуальной модели объекта управления. Выявлены предикторы, влияющие на профессиональную деятельность обслуживающего персонала электросетевых компаний.

The study of psychological predictors of formation of a conceptual model of the control object for maintenance and repair personnel on the basis of two electric grid companies: the joint-stock company LOESK - Electric Networks of St. Petersburg and the Leningrad Region (JSC «LOESK») and the open joint-stock company Network Company Republic of Tatarstan (OJSC «Network Company»). A factor analysis is carried out and a factor is identified that affects the composition of a conceptual model of the control object. Predictors are identified that affect the professional activities of maintenance personnel of electric grid companies.
FEATURES OF EMOTION RECOGNITION BY STUDENTS FROM RUSSIA AND ASIAN COUNTRIES (Intellectual foundations)
Authors: Карабущенко Наталья Борисовна , Сунгурова Нина Львовна , Чхиквадзе Тинатин Владимировна , Пилишвили Татьяна Сергеевна
Published: February 2021

Представлен теоретический анализ основных концепций восприятия выражения лица, раскрыты теории, посвященные особенностям выражения экспрессии, закономерностям восприятия эмоций людьми, специфике интерпретации. Особое внимание уделено кросс-культурным исследованиям, раскрывающим этно-специфические особенности выражения эмоций, «феномен узнаваемости», характер реагирования на определенную экспрессию представителями различных культур, стиль визуального контакта и др. В эмпирической части раскрыты результаты верификации теоретической модели интеллектуальных оснований распознавания эмоций, выявлено общее и особенное в реализации данной модели на двух выборках студентов (России и стран Азии). Общими для выборок являются следующие компоненты модели: социально-личностный аспект структурного компонента, поведенческий аспект содержательного компонента и регуляторная функция. Специфичны для россиян: деятельностный аспект структурного компонента, когнитивный и мотивационный аспекты содержательного компонента; для студентов из стран Азии: метакогнитивный аспект содержательного компонента, динамическая составляющая, функции адаптации и антиципации. Сформулированы практические рекомендации.

Presents a theoretical analysis of psychological concepts of facial perception of emotions, reveals theories of emotion expression, laws of emotion perception and features of its interpretation. Special attention is paid to cross-cultural studies that reveal the ethno-specific features of expression, «phenomenon of recognition», the nature of the response to a specific expression of different cultures, styles of eye contact, etc. Empirical part reveals the results of the verification of the theoretical model of the intellectual foundations of emotion recognition, identifies common and particular aspects in the implementation of this model on two samples of students (from Russia and Asia). Both samples have common components: social-personal aspect of the structural component, behavioral aspect of the meaningful component and regulation function. Specific for Russian students are the activity aspect of the structural component, cognitive and motivational aspects of the meaningful component. Specific for students from Asian countries are the metacognitive aspect of the meaningful component, the dynamic component, the functions of adaptation and anticipation. The article also contains practical recommendations.
RESEARCH OF FACTORS OF THE ORIGIN OF FOOD DISORDERS: CONTENT ANALYSIS OF TEXTS ON THE INTERNET
Authors: Кононов Александр Николаевич , Комиссарова Анастасия Сергеевна
Published: February 2021

Представлены результаты исследования методом контент-анализа опубликованных текстов в одном из сообществ ВКонтакте, представляющим определенную социальную группу, включающую более 134 тыс. участников, предметом общения которых является тема борьбы с лишним весом. Цель исследования - изучение психологических характеристик членов данного сообщества на основе анализа их публикаций, выделение смысловых блоков (контекстов) и определение социальных факторов, оказывающих негативное влияние на возникновение и развитие расстройств пищевого поведения. Контент-анализ позволил установить, что высказывания участников группируются вокруг 7 смысловых блоков: жир, жирный, похудение, ужасное, порции, школа, худеть. Проведенный анализ контекстов позволил подтвердить гипотезу исследования, что значительное влияние на возникновение расстройств пищевого поведения оказывают социальные факторы, в частности семья и близкое окружение (друзья, одноклассники), особенно сильно воздействию социальной среды подвержены девушки-подростки.

Presents the results of a study by the method of content analysis of texts of one of the communities on VKontakte that includes more than 134 thousand participants and devoted to diets, the use of medications to block appetite and dramatic weight loss. The aim of the study was the selection of semantic blocks (contexts), their analysis and determination of factors contributing to the development of eating disorders. Identified 7 semantic blocks around which statements are grouped. As a result of the analysis of the allocated blocks, the hypothesis was confirmed that a significant influence on the occurrence and development of eating disorders is exerted by the family and close circle (friends, classmates), and teenage girls are especially affected by this effect.
VOCATIONAL TRAINING OF FUTURE ENTREPRENEURS AT THE UNIVERSITY
Authors: Погонышев Владимир Анатольевич , Погонышева Дина Алексеевна , Хвостенко Татьяна Михайловна
Published: February 2021

Рассмотрены вопросы профессиональной подготовки бакалавров как субъектов будущей предпринимательской деятельности. Показано, что качество подготовки обучающихся обусловлено социокультурными, психолого-педагогическими и социально-экономическими факторами, включающими трансформацию предпринимательской и общей культуры, гуманизацию образования с опорой на системный, личностно ориентированный, деятельностный, аксиологический, синергетический, компетентностный подходы и формирование цифровой среды. Установлено, что профессиональная компетентность бакалавра как субъекта будущей деятельности в сфере предпринимательства включает когнитивно-деятельностный, мотивационно-ценностный и рефлексивно-коммуникативный компоненты. Обоснованы организационно-педагогические условия профессиональной подготовки студентов как субъектов будущей предпринимательской деятельности, включающие моделирование профессиональной подготовки, учитывая социально-экономические и личностные аспекты с опорой на системный, деятельностный, личностно ориентированный, аксиологический, фрактальный, синергетический и компетентностный подходы; использование цифровых технологий; мониторинг уровня подготовки субъектов будущей деятельности в предпринимательстве, обусловленной образовательными потребностями общества и личности, цифровыми образовательными ресурсами вуза.

Аrticle considers issues of professional training of bachelor 's degrees as subjects of future business activity. It is shown that the quality of training of students is due to sociocultural, psycho-pedagogical and socio-economic factors, including transformation of entrepreneurial and general culture, humanization of education based on systemic, personality-oriented, activity, axiological, synergistic, competent approaches and formation of digital environment. It has been established that the professional competence of the bachelor as a subject of future activity in the sphere of entrepreneurship includes cognitive-activity, motivation-value and reflexive-communicative components. Organizational and pedagogical conditions of professional training of students as subjects of future business activity are justified, including modeling of professional training, taking into account socio-economic and personal aspects based on systemic, activity, personality-oriented, axiological, fractal, synergistic and competent approaches; use of digital technologies; Monitoring the level of training of subjects of future activities in entrepreneurship due to educational needs of society and personality, digital educational resources of the university.
Rhodnius pallescens microsatellite markers for population genetic analysis in Rhodnius ecuadoriensis: preliminary assessment
Authors: Grijalva Mario J.
Published: February 2021

Rhodnius ecuadoriensis Lent & León (Hemiptera: Reduviidae) es el prinicipal vector de    la enfermedad de Chagas en Ecuador, donde la estructura genética de sus poblaciones es poco conocida. Nosotros probamos seis Repeticiones Cortas en Tamdem (RCT) de R. pallescens Barber en poblaciones selváticas y domésticas de R. ecuadoriensis. Dos microsatelites fueron monomórficos, dos dieron resultados ambiguos y dos fueron polimórficos (16 y 19 alelos) y fueron utilizados para análisis. Los resultados de las frecuencias alélicas, AMOVA y los pruebas Bayesianas para genética favorecen la teorí­a de la existencia de una sola población. Estos resultados preliminares sugieren que las poblaciones selváticas y domésticas d R. ecuadoriensis intercambian frecuentemente migrantes. Por consiguiente el control de la Enfermedad de Chagas requiere vigilancia entomológica continua en la costa del Ecuador.
Actividad bactericida del agua de plata coloidal sobre indicadores de calidad microbiológica: un estudio a partir de muestras ambientales
Authors: Puente Balda Marí­a Belén , Gudiño Gomezjurado Marco Esteban , Granda Moreno Elena Isabel
Published: February 2021

El objetivo del presente trabajo fue evaluar la actividad bactericida del agua de plata coloidal sobre los microorganismos indicadores de la calidad microbiológica aislados a partir de muestras de: (i) agua de 16 canales de riego en la provincia de Tungurahua-Ecuador y (ii) los utensilios e insumos de una cocina en una cafeterí­a en Quito-Ecuador. Para esto se confrontó 4 ppm, 10 pmm y 15 ppm de agua de plata coloidal durante 15, 30 y 60 minutos con los crecimientos equivalentes a A625 de 0,08-0,1 de las cepas de: Escherichia coli ATCC 11229, Salmonella Choleraesuis ATCC 10708, Staphylococcus aureus ATCC 6538 y Pseudomonas aeruginosa ATCC 15442. Una vez estandarizada la técnica se comparó la densidad poblacional de: mesófilos aerobios, E. coli -coliformes totales y enterobacterias de 16 muestras de agua de canales de riego y de 11 superficies de preparación de alimentos antes y después de la exposición a 4 ppm, 10 ppm y 15 ppm de la suspensión de plata coloidal. La plata inhibió el crecimiento de todos los grupos microbianos evaluados en los canales de riego excepto en el 31,3% (n=5) de los casos en los que a 4 ppm de plata los recuentos de las bacterias mesófilas aerobias estuvieron en un rango de entre 10x102 UFC/mL y 40x102 UFC/mL. Para el caso de las muestras recolectadas en la cafeterí­a, los recuentos de mesófilos aerobios disminuyeron en el 64,3% (n=9) del total de superficies muestreadas mientras que el número de E. coli - coliformes totales disminuyó en el 93% (n=13) de las áreas muestreadas a partir los 5 minutos de exposición con de 4 ppm de agua de plata coloidal.
Plataforma de Información Geográfica del Centro Internacional de Hidroinformática
Authors:   Centro Internacional de Hidroinformática, Itaipu Binacional-Unesco, Paraguay, Vera Santiago , Alderete María Eugenia ,   Centro Internacional de Hidroinformática, Itaipu Binacional-Unesco, Paraguay
Published: February 2021

La Plataforma de Información Geográfica fue diseñada por el Centro Internacional de Hidroinformática para proporcionar un mejor acceso a información geográfica (IG) de alta calidad entre los funcionarios de la Itaipu Binacional y otros colaboradores vinculados con la gestión de recursos hídricos. La plataforma conjuga un software libre y de código abierto estable y robusta con una interfaz amigable y moderna permitiendo a los usuarios utilizar e interactuar con datos espaciales en el ambiente de trabajo. La Plataforma de Información Geográfica tiene los siguientes objetivos: (1) organizar la información geográfica a través de una Infraestructura de Datos Espaciales (IDE), (2) disponer de la información geográfica a los usuarios interesados, (3) promover la interacción entre los diferentes usuarios de información geográfica. Algunas de las funcionalidades de la Plataforma de Información Geográfica son la carga de datos, metadatos, documentos y la creación de mapas. Los datos pueden ser visualizados y compartidos por los usuarios, dependiendo de las restricciones previamente establecidas. La creación de grupos de usuarios facilita el uso, la gestión y el control de calidad de datos de la plataforma. Una de las principales ventajas de la Plataforma de Información Geográfica es la flexibilidad con la que los desarrolladores de software pueden mejorar sus características y adaptarlas a las necesidades de los usuarios.
Management of a transport company during the Covid-19 pandemic
Authors:   Rzeszow University of Technology, Faculty of Management, Department of Management Systems 5 and Logistics, BEŁCH Paweł
Published: February 2021

Purpose: The end of the first quarter of 2020 is the beginning of a new, difficult time in the functioning of transport companies, as well as the entire Polish and world economy. The appearance of Covid-19 (SARS-CoV-2) resulted in a number of market restrictions and a sharp decline in transport orders. Enterprises had to change the way they were managed and operated, had to adapt to a different economic reality in order to continue to prosper. The aim of the article is to define the essence of managing a transport company in the new market and economic conditions that appeared during the Covid-19 pandemic. Design/methodology/approach: The research procedure included review of polish and foreign literature, analysis of legal acts, questionnaire research, analysis of the content of internal documents of transport companies, method of analysis and synthesis, case study, methods of inductive and deductive reasoning. The article presents the results of scientific research on the impact of Covid-19 on the management and decisions made in a transport company. Findings: The high level of impact of the Covid-19 pandemic on the management of a transport company has been demonstrated. The factor that most influenced the management and decisions of transport companies is the decline or fear of a decline in contracts for transport services. Transport companies are afraid of the further negative effects of the pandemic, and therefore do not want to take out investment loans in order to develop the company. The article discusses the activities of transport companies and the management of a transport company in crisis conditions. Research limitations/implications: The article presents a survey carried out in Polish transport companies from the Podkarpackie and Lubelskie voivodships. Therefore, the research results concern the area of south-eastern Poland. Practical implications: The results of the research may be helpful for managers of transport companies (management decisions made) in order to limit the negative impact of the Covid-19 pandemic on their business activities. Originality/value: The presented research and conclusions provide practical guidance to managers about what decisions and actions can improve the economic condition of their transport companies in the difficult period of the Covid-19 pandemic, based on the example of the analyzed transport companies.
Opinions of Polish students on the need for the transition to distance learning when facing the global pandemic Covid-19
Authors:   Technical University of Czestochowa, PUTO Agnieszka
Published: February 2021

Purpose: The objective of the article is to present the condition of Polish universities and trends occurring in distance learning and e-learning. The results of the research conducted among students of Polish universities (N-2226), who were forced to the transition to distance learning from day to day, are presented in the article. Using well-known statistical measures, the correlations between the selected factors have been indicated. The research results on the correlations between the following variables have been presented – the opinions on the need for the transition to distance learning during the pandemic and:  gender,  age,  taking up employment in addition to studying,  an opportunity to study in a separate room. Design/methodology/approach: For the research purposes, a well-known Internet Survey Panel was utilized, which was used to create and manage the surveys as well as to collect the results. The bivariate analysis was used, the objective of which was to determine the empirical relationship between the selected variables. In the research, among others, the following were used: Chi-Square Test for Independence, Phi-Square Test for Independence, Spearman’s rank correlation test. For the data with the responses specified on the ordinal scale in the correlation analysis, Spearman’s rank correlation coefficient was used. Findings: The change in the teaching method which has been experienced in relation to the global pandemic may prove to be a breakthrough and give rise to changes in student education So as to educate the future staff of Industry 4.0 using distance learning. Increasing students’ involvement in the learning process may help them acquire competences useful in their professional life more effectively
Lectura exegético-teológica de los viajes de Elías y el movimiento de YHWH en 1 Reyes 19, 1-18
Authors: Mauricio Urbina Villamil
Published: February 2021

Este artículo presenta una propuesta de lectura exegético-teológica del texto de 1 Reyes 19, 1-18 a partir de la categoría movimiento. La dinámica polar entre movilidad e inmovilidad en las acciones de los dos protagonistas del relato, el profeta Elías y YHWH, su Dios, conducen al lector a descubrir la riqueza de un texto cargado del choque entre la enérgica fuerza divina con la estática debilidad humana. El movimiento mostrado en el relato va más allá del simple desplazamiento físico, sino que involucra esferas de mayor profundidad, sobre todo en el campo psicológico y espiritual. Partiendo de una lectura atenta del texto hebreo, se procede a identificar algunas estrategias narrativas que permitan hacer claridad sobre su mensaje final. La investigación se enriquece a través del diálogo con diversos exégetas contemporáneos, con el fin de hacer brillar el significado y la relevancia actual este relato.
Antibacterial Activity of Methanol Extract of Sargassum polycystum on Escherichia coli and Staphylococcus aureus
Authors: Ghazali Mursal , Zaki Muhammad , Hidayati Ernin
Published: February 2021

Macroalgae is a commodity that is used as food, medicine, fertilizer and other materials in industries. Macroalgae in the medical world have the potential to be anticancer, antiviral, antifungal and antibacterial. One type of macroalgae that has the potential as an antibacterial source is Sargassum polycystum. This study aims to analyze the ability of the methanol extract of S. polycystum to inhibit the growth of bacteria (Escherichia coli and Staphylococcus aureus) and analyze the potential compounds contained in the methanol extract of S. polycystum. This research is an experimental study using a completely randomized design. Extraction method by maceration. The test concentrations used were 20%, 40%, 60%, 80%, positive and negative control. While the test method uses a good diffusion method. Data were analyzed using description and SPSS application. The results showed that the methanol extract of S. polycystum had better inhibition against S. aureus growth than E. coli. The methanol extract concentration of S. polycystum, which had the best inhibition against S. aureus and E. coli was 80%. Metabolites content on S. polycystum extract is Tetradecanoic Acid, Loliolide; Hexadecanoid Acid, Methyl Ester, 9-Hexadecanoid Acid, Hexadecenoic Acid, 8-Octadecanoic, Methyl Ester, 5,8,11,14-Eicosatetraenoic Acid and Ethyl Ester.
KAPSARC Oil Market Outlook
Authors:   KAPSARC (King Abdullah Petroleum Studies and Research Center)
Published: February 2021

Total global oil demand is expected to increase year-on-year (YoY) by 4.2 million barrels per day (MMb/d) in 2021 and further grow by 3.5 MMb/d in 2022, returning to 2019 levels by the third quarter (Q3) 2022. The International Monetary Fund (IMF) predicts economic growth of around 5.4% in 2021, compared with a decline in real gross domestic product (GDP) in 2020 of -4.4%. However, KOMO estimates a forecast more in line with the OECD’s outlook for growth (4.2%), which presumes that GDP levels will only reach 2019 levels by the end of 2021.
Uji Aktivitas Analgesik Minyak Ikan pada Mencit Putih (Mus musculus) Jantan Galur BALB/c dengan Metode Writhing Test
Authors: Amilia Risca , Kresnamurti Angelica , Faizah Ana Khusnul
Published: February 2021

Minyak ikan merupakan sumber EPA dan DHA yang berasal dari sumber daya laut. Kapsul minyak ikan merupakan salah satu nutraseutikal untuk memenuhi kebutuhan omega-3 dan omega-6. Penelitian telah dilakukan menggunakan minyak ikan salmon yang mengandung EPA dan DHA. Tujuan dari penelitian ini adalah untuk menentukan aktivitas analgesik pada tikus putih jantan (Mus musculus) strain BALB/c. Sejumlah 25 ekor tikus putih jantan dibagi menjadi 5 kelompok, masing-masing kelompok terdiri dari 5 ekor tikus putih jantan. Kelompok kontrol negatif diberi kombinasi emulsi Tween 80 dan Span 80, kelompok kontrol positif diberi aspirin, dan kelompok perlakuan diberi emulsi minyak ikan salmon dengan dosis 20, 30, dan 40 mg/kg BB. Metode yang digunakan pada penelitian ini adalah writhing test dengan menginduksi tikus putih jantan dengan asam asetat 0,6%. Hasil penelitian menunjukkan bahwa emulsi minyak ikan salmon dengan dosis 20, 30, dan 40 mg/kg BB memiliki persentase hambatan nyeri masing-masing sebesar 29,44; 42,64; dan 52,59%. Dapat disimpulkan bahwa emulsi minyak ikan salmon memiliki aktivitas analgesik.
Analisis Rhodamin B pada Lipstik Impor yang Beredar di Kota Batam secara Kromatografi Lapis Tipis dan Spektrofotometri UV-Vis
Authors: Elfasyari Trie Yuni , Putri Mutia Amelia , Andayani Regina
Published: February 2021

Zat warna rhodamin B adalah bahan pewarna yang dilarang penggunaannya dalam sediaan lipstik karena memiliki potensi karsinogenik dan merusak organ hati. Penelitian ini bertujuan untuk mengetahui secara kualitatif dan kuantitatif zat rhodamin B dalam sediaan lipstik impor yang beredar di Pasar Kota Batam. Metode yang digunakan adalah kromatografi lapis tipis untuk mengidentifikasi senyawa rhodamin B dengan menghitung nilai Rf dari fluoresensi bercak di bawah sinar ultraviolet. Penentuan kadar rhodamin B dilakukan dengan alat spektrofotometer UV-visibel dengan mengukur absorban pada panjang gelombang maksimum 548,5 nm. Konsentrasi larutan baku standar rhodamin B adalah 0,8; 1,2; 1,6; 2,0; dan 2,4 µg/mL. Didapatkan persamaan kurva y=0,0128+0,276x dengan r=0,9999. Hasil analisis kualitatif dari 15 merek sampel lipstik didapatkan dua merek lipstik yang teridentifikasi positif rhodamin B yaitu lipstik I dengan Rf 0,78 dan lipstik L dengan nilai Rf 0,77. Penentuan kadar rhodamin B dari masing-masing lipstik didapatkan kadar sebesar 73,225 µg/g pada lipstik I dan 92,61 µg/g pada lipstik L.
Analisis Sistem Penyimpanan Obat di Instalasi Farmasi Dinas Kesehatan Kabupaten Rokan Hulu Tahun 2018
Authors: Anggraini Deni , Merlina Syarifah
Published: February 2021

Penyimpanan obat yang baik  penting untuk menjaga persediaan obat agar terhindar dari kerusakan, kadaluwarsa, dan untuk menjaga mutu. Tujuan penelitian ini adalah untuk mengetahui kesesuaian sistem penyimpanan obat di Instalasi Farmasi Dinas Kesehatan Kabupaten Rokan Hulu berdasarkan 5 indikator penyimpanan obat. Penelitian ini merupakan penelitian observasional yang bersifat deskriptif dengan pengumpulan data secara retrospektif dari bulan Januari sampai Desember 2018. Pengumpulan data dilakukan dengan observasi dan telaah dokumen. Hasil penelitian menunjukkan bahwa untuk parameter sistem penataan gudang dan parameter kesesuaian antara obat dengan kartu stok hasilnya kategori sangat baik. Persentase nilai obat rusak dan kadaluwarsa memenuhi persyaratan yaitu <1% (0,33%). nilai Turn Over Ratio (TOR) 0,85 kali, dan persentase stok mati 2,78% belum memenuhi persyaratan (0%).
Evaluasi Penggunaan Antibiotik Infeksi Saluran Pernapasan Atas pada Anak di Puskesmas Olak Kemang Kota Jambi Tahun 2018
Authors: Dewi Rasmala , Dewi Rasmala , Sutrisno Deny , Sutrisno Deny , Medina Fhatia
Published: February 2021

Prevalensi penyakit ISPA (Infeksi Saluran Pernapasan Atas) tahun 2018 di Provinsi Jambi sebesar 5,5%. Hal ini berdampak pada meningkatnya kunjungan berobat ke Puskesmas dan penggunaan obat, salah satunya antibiotik. Hasil survey di Puskesmas Olak Kemang, Kota Jambi menunjukkan masih ada ketidakrasionalan dalam penggunaan antibiotik pada penderita ISPA, khususnya pada anak. Penelitian ini bertujuan untuk mengevaluasi karakteristik demografi, pola, dan kerasionalan penggunaan antibiotik pada anak di Puskesmas Olak Kemang, Kota Jambi Tahun 2018. Sampel dalam penelitian yaitu anak berusia 5-11 tahun, yang didapat dari data register harian dan data sekunder berupa rekam medik dan resep obat. Pengambilan data secara retrospektif, dan data dianalisis dengan kriteria kerasionalan penggunaan obat yang disesuaikan dengan acuan Pharmaceutical Care untuk infeksi saluran pernapasan. Terdapat 70 kasus anak yang didiagnosis ISPA, dengan penggunaan antibiotik terbesar berupa amoksisilin (88,5%). Kerasionalan penggunaan antibiotik, meliputi parameter ketepatan indikasi, ketepatan pasien, ketepatan obat, ketepatan dosis berdasarkan frekuensi pemberian, dan durasi pemberian, masing-masing dengan skor 100; 98,5; 54,2; 48,5; dan 1,4%. Dapat disimpulkan bahwa kerasionalan penggunaan antibiotik pada anak di Puskesmas Olak Kemang, Kota Jambi untuk diagnosis ISPA, dari empat parameter ketepatan hanya ketepatan indikasi yang dinilai sudah rasional.