bluuebunny/crossref_metadata_2025 huggingface dataset:
Políticas Públicas de Educación Rural y Desarrollo territorial: Una Revisión Sistemática de la Literatura (2012-2023).
Authors: Suárez Caro Laura Katherine , Camacho Bonilla Aureliano
Published: July 2023

Para identificar las discusiones académicas generadas sobre políticas gubernamentales de educación rural y desarrollo territorial, se realizó una revisión sistemática de artículos publicados en Scopus entre 2012 y 2023. Las investigacio[1]nes han aumentado en los últimos años y aplican principalmente metodología cualitativa. Los debates giran alrededor de los desafíos de la educación rural y los resultados de la implementación de estas políticas públicas. Se identificaron tres tendencias desde las que se aborda la educación rural y el desarrollo: Incorporación de los Objetivos de Desarrollo Sostenible (ODS) en prácticas pedagógicas, iniciativas productivas rurales que generan conocimiento y reflexiones sobre el impacto de la educación rural en el desarrollo de los territorios. Finalmente, se analizó la relación de la educación rural con las comunidades y el uso de las Tecnologías de la Información y las Comunicaciones (tic) en contextos educativos rurales.
Transferencia y divulgación del conocimiento:
Authors: Merchán Avenia Johanna Andrea , Ramírez Triana Nelida Yaneth
Published: July 2023

La transferencia del conocimiento presenta etapas metodológicas como producir, transformar, socializar e integrar la información adquirida y aplicable a las necesidades humanas; es un proceso que involucra la participación consciente en la creación de conocimiento, la divulgación del saber por parte del emisor y la adquisición y aplicación de este por parte del receptor. Su interés conceptual es la divulgación del conocimiento científico y tradicional en una población. Por tanto, en este artículo se pretende resaltar la transversalidad conceptual de la transferencia del conocimiento, desde el desarrollo de un análisis de revisión bibliográfica apoyada en la técnica de la bibliometría de 17 artículos debidamente indexados. En la primera fase se seleccionaron los artículos en un periodo de doce años, en el que se analizaron sus indexaciones, países y años de publicación influyentes. En la segunda fase se seleccionó la bibliografía de dichos artículos, relacionada con la temática y que correspondiera a un rango temporal de catorce años. Aquí se desarrolla un análisis de datos representativos como año, país, autores y filiaciones. Este análisis evidencia una mayor influencia en la investigación del concepto por países como Canadá (MacMaster University) y México (Universidad Nacional Autónoma de México y Centro de Investigación en Alimentación y Desarrollo); con una prevalencia de año por publicación entre 2009 y 2014.
The Janus Face of Valuation: Global Performance Indicators as Powerful and Criticized Public Measures
Authors: Ringel Leopold
Published: July 2023

The article conceptualizes global performance indicators as public measures that are powerful but also receive a wide range of criticism. Global performance indicators derive their power from combining three analytically distinct elements: (a) commensuration (comparing performances on a common metric), (b) visual simplification (presenting performances in an appealing format), and (c) serialization (framing performance as a continuous developing property). However, the very same elements are often subject to criticism. The producers of global performance indicators, therefore, defend methodologies and the validity of commensurated numbers, meet charges of visual oversimplification by professing sobriety and nuance, and balance temporal continuity and discontinuity. By conceptualizing global performance indicators as powerful and criticized public measures, the article draws attention to the Janus face of valuation, which the producers must tackle continuously. Investing considerable time, energy, and resources, these organizations are a key feature of today’s vast indicator culture.
Social Inclusion Beyond Education and Work: Migrants Meaning‐Making Towards Social Inclusion
Authors: Nyström Sofia , Fejes Andreas , Mešić Nedžad
Published: July 2023

In public discourse, the social inclusion of migrants is often regarded as a challenge demanding migrants to increase their engagement in adapting to the new host country. Such imaginaries commonly declare migrants as being unwilling to acquire language skills and specific cultural values. In parallel, formal education is often proposed as the single most important remedy to inclusion, which generally solely implies labor market participation. However, there is a range of other, often neglected, practices that migrants themselves regard as important for their social inclusion in society. This article aims to analyze what practices are assigned meaning by newly arrived migrants in Sweden on their path toward social inclusion in the country. This is a longitudinal interview study with 19 newly arrived adult migrants that were interviewed on two occasions, three years apart. Drawing on a sociocultural perspective, we understand social inclusion as an ongoing process by which individuals become members of different communities. The result shows that important for social inclusion is access to valuable relationships and close social ties. These relations are important in all communities in which the migrants participate. The analysis illustrates three different communities, outside of formal education and employment, that migrants ascribe meaning to concerning language learning and social inclusion. These communities are sports, internships, and civil society engagements. Through its longitudinal design, this study also illustrates how migrants’ narratives and their meanings shift with time and how migrants relate to these communities over time.
USING NEARPOD TO TEACH SCHOOLCHILDREN WITH SPECIAL NEEDS: REVIEW OF THE INNOVATIVE ONLINE LESSON IN UKRAINIAN LITERATURE
Authors:   Taras Shevchenko national University of Kyiv, Zyazyun Laryssa , Zakhariia Anastasiia ,   Taras Shevchenko national University of Kyiv
Published: July 2023

Introduction. Since 2022, thousands of Ukrainian educators have been facing a dramatic challenge – training during the war. The lack of approaches, methods or tools that would be effective in organizing the instruction of children affected by injuries that caused physical limitations turned out to be an even greater challenge. Inclusive education has experienced an urgent need to use new, effective online tools for distance learning of children without and with special educational needs (SEN) as well as encouraging them to communicate in Ukrainian literature lessons. Thus, the purpose of the article is to investigate the educational potential and effectiveness of the Nearpod online platform while teaching secondary school students with SEN. Methodology. Methodologically, the lesson relies on the concept of inclusive education in Ukraine, which is implemented by the Order of the Ministry of Education and Culture of Ukraine «On approval of the concept of inclusive education development « (2010). The piloting of the lesson in Ukrainian literature for the 6th graders with special educational needs was carried out in the conditions of online learning in the format of a video conference using the Nearpod educational platform Results and Discussion. The lesson piloting has proved the effectiveness of the NEARPOD platform in distance learning of students with SEN. Based on the analysis of the latest research into inclusive education, the authors have managed to implement the appropriate information technologies to overcome communicative isolation of children with musculoskeletal disorders and physical injuries. The Nearpod educational online platform has enabled equal involvement of all schoolchildren in game and competitive forms of learning, shaping schoolchildren’s responsibility for the success of all team members and respect for the intellectual and emotional contribution of each student to overall class achievements..
Examination in the Conditions of the Moratorium Regime
Authors: Korepina A. V.
Published: July 2023

The paper attempts to theoretically substantiate a new legal institution in the system of administrative law, which requires independent scientific understanding. The author identifies the essential features of the moratorial administrative law regime, allowing to determine its place and purpose in the system of administrative law regulation. In the process of analyzing the urgent legal norms adopted in the Russian Federation in recent years, it has been established that many administrative law institutions are implemented within the framework of the moratorium regime. One of them is the Institute of expertise in the field of public administration. On the one hand, examination as a professional tool for assessing legally significant circumstances and facts necessary for making a public management decision provides an additional safeguard of compliance with the interests of the state, society and the individual in the implementation of economic or other activities. On the other hand, it acts as an administrative barrier, the overcoming of which requires additional time, labor, and financial costs from the participants of legal relations. In this regard, the establishment of moratorium measures in the implementation of the institute of expertise in the field of public administration should be recognized as justified in emergency conditions. Special attention is paid to the characteristics of the main types of the moratorium in the field of state expert activity.
The Principle of Citizens’ Participation in the Budget Process
Authors: Boltinova O. V.
Published: July 2023

The paper explains the principle of citizens’ participation in the budget process in the context of the general principles of the budget system of the Russian Federation. Today, this principle is implemented in our country through the procedure of public hearings. They are held annually when the budget law is being developed, or during the period when a report on its implementation is being drafted. The author of the article points out that in the legislation there are special principles of the budget process applicable to budget-procedural activities and activities of public entities. In author’s opinion, the principle of citizens’ participation in the budget process should take a special place in the list of special principles of the budget process. In practice, in particular, the principle of citizens’ participation in the budget process is implemented through the launch of initiative budgeting programs. This is especially noticeable at the regional and municipal levels. The article traces the idea that the principle of citizens’ participation in the budget process is currently not fully implemented. Therefore, it is necessary to consolidate the legal norms providing for this principle at the legislative level.
Conditions for the Recognition and Enforcement of Foreign Judgments on Disputes Involving «Sanctioned» Persons in the Russian Jurisdiction
Authors: Gilmanova V. I.
Published: July 2023

The paper aims at studying the legal nature and procedure for applying the rules of arbitration procedural legislation, which determine the conditions for the recognition and enforcement in Russia of foreign decisions on disputes involving «sanctioned» persons. These conditions are both an additional guarantee and a means of protecting the rights of these persons. The author argues that the legislator’s admission of the issuance of an exequatur to a foreign decision taken at the suit of a «sanctioned» person is justified, since the said person himself initiated a lawsuit in a foreign jurisdiction. The objections of the «sanctioned» person against the consideration of the case by a foreign court with his participation are characterized as one of the procedural and legal means of protecting the rights of the defendant, aimed at completing the consideration of the case without making a decision on the merits. The paper concludes that the fact of filing these objections in a foreign court is assessed taking into account the procedural norms of the place where the case is heard, the obstacles in their statement due to the effect of sanctions and the applicant’s good faith.
Ecosystem of Preliminary Investigation
Authors: Smushkin A. B.
Published: July 2023

The paper states that the digital transformation of the investigation procedure requires new, effective tools, including those that accumulate the network capabilities of various law enforcement agencies. One of the leading tools in this area are digital platforms. However, the use of not isolated digital platforms of various bodies, but their collaboration into a full-scale digital ecosystem will have a greater synergistic effect. At the same time, it is stated that the prospective ecosystem under consideration should be composed of digital platforms of all three main types: instrumental, infrastructure and applied digital platforms. The paper discusses the essence of digital ecosystems. Within the ecosystem of the preliminary investigation, the author provides for the allocation of at least three main areas (blocks): criminal procedure, organizational (office work) and forensic. Within the framework of the organizational direction, the author considers issues related to the automation of receiving reports of crimes, solving logistical issues of sending guard services, investigative teams, as well as unmanned devices to the scene, expanding the possibilities of electronic office work, automating the selection of the required legislation and judicial practice. In the procedural direction, the use of elements of an electronic criminal case, remote investigative actions (with the use of not only video conferencing, but also other technologies) within the ecosystem is considered. Much attention is given to the use of electronic evidence. Within the framework of the forensic direction, the author considers it important to analyze open databases and Internet information using big data analysis technologies. It also seems reasonable to pair this ecosystem with the Safe City program with the obligatory use of face recognition systems. Intelligent recommender systems and decision support systems are considered. Attention is also given to the study of virtual traces.
Modern International Legal Discourse Regarding the Use of Lead
Authors: Norboeva T. V.
Published: July 2023

The problems of environmental protection are still one of the most pressing international legal issues. Among the causes of environmental pollution, and hence the violation of human rights and harm to public health, is the use of lead. The presence of lead in the human body increases the risk of cognitive decline, disruption of the endocrine and reproductive systems, etc. However, young children are most at risk of lead poisoning. Issues of regulating the handling of lead (individually or as part of a group of heavy metals) are the subject of special attention in international law. One of the burning issues is the limitation of the use of lead in paints, implemented through a global partnership of governmental, non-governmental and private organizations and actors. According to the author, this way of solving environmental problems involves the development of a «multi-level» international legal management in the field of handling chemicals. The paper emphasizes the need to take coordinated measures to limit the use and eliminate lead-containing paints, which implies the abandonment of voluntaristic approaches by states to the establishment of regulatory limits for the content of lead in paints. Two ways of resolving the problem are proposed: the creation of an international agreement of a binding nature (following the example of the UN Convention on Mercury), and the prolongation of the practice of global partnership. The main measure of the effectiveness of such a method should be recognized as a sufficient degree of protection of human rights and, in a broader sense, compliance with the principles of international law as a whole.
Three-dimensional reconstruction of the pelvic bones on MRI scans
Authors: Ikryannikov Egor O.
Published: July 2023

BACKGROUND: Pelvimetry is an important part of the obstetric examination for predicting a mismatch between the size of the fetus and the mothers pelvis, which leads to difficulty or impossibility of vaginal delivery. Contracted pelvis is one of the main causes of maternal birth trauma and perinatal morbidity and mortality.
AIM: To create a computer vision model for automatic segmentation and three-dimensional (3D) reconstruction of the pelvic bones.
METHODS: A 3D U-Net-based neural network was used and trained on T2 weighted images in frontal projection (repetition time, 7500; echo time, 130; slice thickness, 4mm; field-of-view, 4039; matrix, 256256). The sample size covered 49 patients. The training and test samples included 42 and 7 examinations, respectively. The segmentation of areas of interest was done manually and verified by a specialist. The sample size was justified by achieving representativeness of the data for obtaining a qualitative model (according to the SorensenDice coefficient).
RESULTS: 3D reconstructions of the pelvic bones were obtained. The average Sorensen-Dice coefficient on the accuracy of pelvic bone segmentation in the test sample was 0.86. The result justified the use of a 3D U-Net-based neural network as a tool capable of perceiving a 3D structure of images and conducting qualitative segmentation. The results allow further work on automating the determination of key points at reconstructions.
CONCLUSIONS: A computer vision model for automatic segmentation of the pelvic bones to obtain 3D reconstruction of images was created. This enabled the next stage of the study, i.e. the development of a model for determining the key points in the images and the distances between the points.
Digital diagnostics: A computer application for lymph node metastases in cervical cancer
Authors: Kuznetsov Anton I.
Published: July 2023

BACKGROUND: Since 2020, staging accuracy improvements in cervical cancer (CC) revealed that major errors occur due to missed metastases to regional lymph nodes. The presence or absence of metastases seriously affects the staging of cancer and, consequently, its treatment methods, since metastases make cancer inoperable.

AIM: To develop an application to help the doctor in predicting metastases to regional lymph nodes in CC, with the ability of installing on any personal computer regardless of the operating system (Windows, Linux, or Mac OS) and saving data about the patients.

METHODS: The development was performed on the .NET platform (framework v4.7.2), by means of C# language, based on a proprietary prognostic model using seven blood parameters such as erythrocyte sedimentation rate, erythrocytes, hemoglobin, fibrinogen, D-dimer, and platelet aggregation with adenosine diphosphate and soluble fibrin monomer complexes.

RESULTS: A window application was developed that automatically calculates the probability of metastases to regional lymph nodes in СС and provides the ability to save the data from the input form and the predicted value into TXT and/or CSV files. TXT and CSV formats are supported in various operating systems. The .txt file allows each individual patients prognosis results to be saved in a separate file for easy printing and attachment to the patients electronic or paper medical record. The CSV file format enables the aggregation of data of all patients by adding line-by-line data from the input form to the end of the file.

CONCLUSIONS: The developed application facilitates the process of using the patented formula to diagnose metastases to regional lymph nodes in СС at the early stages of examination, which allows choosing the optimal tactics and, consequently, improving the prognosis of the disease.
Assessment of chewing efficiency with artificial intelligence
Authors: Levashov Nikita E. , Gus’kov Alexander  V. , Oleynikov Aleksandr  A. , Domashkevich Nikolai  S.
Published: July 2023

BACKGROUND: Artificial intelligence (AI) is a system based on machine learning of neural networks. AI structure resembles nerve tissue, having the so called neurons, i.e. mathematical codes. A neural network has three levels, including the input layer (information enters the system), the hidden layer (multidimensional data is analyzed), and the output layer (the system generates conclusions). Current neural networks use a perceptron, i.e. a neuron consisting of a large number of interconnected input and hidden layers, which makes the system capable of self-learning and analysis of non-linear data and generalization and processing of incomplete information, including the method of projection onto latent structures.
AIM: To develope a program based on multivariate data analysis to determine the chewing efficiency at the stages of prosthetics.
METHODS: In 2016, the Department of Orthopedic Dentistry and Orthodontics developed and tested a program for determining chewing efficiency based on the analysis of digital occlusiograms obtained by scanning dental prints on a wax plate. The results were processed by mathematical methods of multivariate data analysis using the projection on latent structures (the partial least-squares [PLS-2] model), which allowed assessing the relationship between the value of chewing efficiency and the area and brightness characteristics of the areas corresponding to occlusal contacts. The program compared the measurement results with the reference occlusiograms in the database and gave a conclusion. The experiments yielded statistically significant results for the efficiency of the program compared to traditional chewing tests. Due to the relevance of implementing AI in orthopedic treatment, the decision was made to improve the training methods of the program to update the existing array of reference data. Starting in 2019, 24 occlusiograms were added to the previously received data with dental defects from 9 to 12 teeth. Using an expanded database, the program, when analyzing the occlusiogram of a new patient, allowed to consider changes in chewing efficiency obtained earlier with the Trezubov chewing test for various defects of the dentition and compare the reference and minimally achievable values of chewing efficiency. The program algorithm was verified by the researchers using the classical Trezubov chewing test. Chewing efficiency was measured as a percentage.
RESULTS: The obtained combinations of the digital algorithm parameters for assessing chewing efficiency resulted in increased accuracy in the range of 4%6% compared to the traditional Rubinov and Ryakhovsky chewing tests.
CONCLUSIONS: A digital algorithm for assessing chewing efficiency allows for quick and accurate assessment without the use of time-consuming analog tests.
Multidisciplinary approach to postmortem diagnostics
Authors: Lozina Milena V. , Shiripenko Ivan  A. , Sidorova Olga  A. , Soldatova Antonina  A. , Tarasova Polina  A. , Kuznetsov Vasiliy  A. , Malygin Bulat  V.
Published: July 2023

BACKGROUND: The technique that allows detecting various pathologies and clearly identifying the cause of death and other associated diseases without disturbing the integrity of the skin refers to postmortem radiological diagnostics and is called virtopsy. The number of autopsies decreases worldwide, which creates the need to use alternative non-invasive methods, including virtopsy. The main method of postmortem radiology is multislice computed tomography (CT), with its advantages including high sensitivity to bone pathology. Postmortem radiological diagnostics allow supplementing the classical autopsy. This multidisciplinary approach helps visualize a wide variety of pathologies and assist the pathologist in the diagnostic search.
AIM: To assess the possibility of applying radiological diagnostic methods in the pathological anatomical practice and features of non-invasive autopsy (virtopsy) and its differences from the classical autopsy.
METHODS: The archival material including macro preparations of two lower limbs with tumor-like masses of unclear genesis (the upper third of the femur and the calcaneal tuber) was used. The biomaterial was previously encased in a specially treated gelatin medium, which ensured its preservation and left parts of the CT scanner intact. Multislice CT was used for radiological assessment of the preparations. From the primary CT sequences obtained, scans with the best visualization in the bone and soft tissue windows were selected, and three-dimensional (3D) reconstruction was applied. Scans and 3D reconstructions of images of tumor-like masses of the heel and thigh bones were obtained. Interpretation of the borders of the mass, characteristics of morphology and possible source of growth of the neoplasm allowed assuming a malignant nature of the tumor, suggesting its bone origin. Further histologic examination in both cases confirmed the neoplasm (osteogenic sarcoma).
RESULTS: CT scans and 3D reconstructions of images of tumour-like masses in the heel and femur were obtained. The interpretation of the boundaries of the mass, the morphological characteristics and the possible source of growth of the neoplasm suggested a malignant nature of the tumour, suggesting a bony origin. Further histological evaluation in both cases confirmed the nature of the neoplasm (osteogenic sarcoma).
CONCLUSIONS: The use of postmortem radiological diagnostic elements provides a sufficiently accurate verification of the nature of some pathologies. However, the absence of tissue damage and disturbances of intact topographic characteristics play not the least role in the postmortem diagnosis. In contrast to autopsy, this technique allows to return to the original appearance of the structures examined and, if necessary, start the diagnostic search anew. Moreover, specialists from other regions can be remotely involved by sending the data of CT scanning.
A chat-bot in rheumatoid arthritis treatment control
Authors: Prokofeva Yuliya A. , Zheleznykh Elena  A. , Menshikova Irina  V.
Published: July 2023

BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune rheumatic disease with joint damage and systemic manifestations, which worsens the quality of life and life expectancy, leading to disability in the absence of effective therapy at a young age. The goal of RA treatment is to achieve remission/low disease activity. Frequent monitoring of the disease is needed (every 13 months until the goal is reached, then every 36 months), which is not always possible due to remoteness of residence, financial capabilities of patients, and epidemic situation. Remote monitoring appears to be a possible solution to the problem; however, the effectiveness of telemedical technologies in the treatment of patients with RA is not sufficiently studied.
AIM: To investigate the effectiveness of remote-control treatment of patients with RA of high and moderate activity using a chat-bot.
METHODS: An algorithm for remote monitoring and communication with RA patients was developed. The chat-bot performs a survey every month and out-of-schedule when the patients condition worsens and provides the data to the doctor in a convenient form. Regular assessments of RA activity, functional impairment, and quality of life and correction of recommendations if necessary are made. All participants are coded, with only the doctor having access to personal data. In remote (60 patients) and traditional (30 patients) control groups, the time to remission/low disease activity will be compared. Adherence to the chat-bot and cost-effectiveness analysis will be studied.
RESULTS: Twenty patients were trained on how to use the chat-bot and have been using the program for 2 months. The condition is monitored and online counseling is provided if necessary. Nineteen patients had no difficulties when working with the chat-bot. One patient needed a second consultation on how to use the chat-bot. Half of the patients were over 60 years old. Most patients prefer remote counseling to a face-to-face appointment. Patients report an improved understanding of the disease, treatment principles, and methods of self-assessment of the joint condition. Remote monitoring is planned to achieve stable control of RA activity by timely detection of exacerbations and therapy correction and assessment of the need for hospitalization, which will help to reduce the period of remission/low RA activity. The economic cost of treating RA is expected to be reduced.
CONCLUSIONS: Remote monitoring using a chat-bot to improve the effectiveness of RA treatment is an important aspect of current rheumatology and a potential method for increasing the availability of medical care. The results may serve as a basis for further research on telemedical technologies and the development and application of personalized algorithms for monitoring, prevention, and treatment of patients with rheumatic diseases.
Impact of heat waves and cold spells on mortality in cities located in the Russian Arctic macroregion
Authors: Shaposhnikov Dmitry A. , Revich Boris A.
Published: July 2023

BACKGROUND: Climate warming in Russia is most pronounced in the Arctic, where it is accompanied by an increase in the frequency and duration of heat waves. This emerging risk factor for the health of the population in major cities has not yet received adequate scientific attention. To effectively plan for adaptation to these phenomena, it is crucial to understand their specific impacts in regions with different climate types. Therefore, comprehensive analysis of the associations between climatic factors and health is needed for informed decision-making and strategic adaptation planning.
AIM: To assess the impact of heat waves and cold spells on excess age-specific mortality within the urban populations of the Arctic macroregion. Furthermore, we analyzed the potential differences in the studied outcomes across climate types, ranging from marine to continental.
METHODS: We analyzed the daily counts of deaths in Arkhangelsk, Magadan, Murmansk, and Yakutsk from 1999 through 2019. Poisson generalized linear regression models were employed to determine the relative mortality risks during heat waves and cold spells. All models accounted for potential lagged effects, seasonal and weekly patterns, and long-term mortality trends. Pearsons chi-squared tests were used to study the differences between the effects of heat and cold, as well as site-specific and age-specific variations in mortality.
RESULTS: Effects of the studied climatic phenomena were more pronounced in continental than in marine climate. The age group 65+ years was more susceptible to the effects of extreme heat and cold than the middle-age group. Cold spells had a greater impact on the health of the residents of Murmansk, Arkhangelsk, and Magadan than heat waves, while the opposite was observed in Yakutsk. Cerebrovascular mortality during heath waves was 1.69 (95% CI: 1.342.13) times as high as during periods with normal temperature in the age-group 65+ in Yakutsk while cold spells were associated with 1.54 (95% CI: 1.182.01) greater risk of death from respiratory causes in the same age-group in Arkhangelsk.
CONCLUSION: Our findings can be utilized by public health authorities to effectively prevent further fatalities among subarctic populations during heatwaves and cold spells.
Gender differences in sensitization to formaldehyde among urban adolescents in relation to parental chemical exposure
Authors: Masnavieva Liudmila B. , Efimova Natalia V. , Kudaeva Irina V. , Zhurba Olga M.
Published: July 2023

BACKGROUND: The burden of sensitization and allergies increases every year. The development of allergopathology can be influenced by various external factors, including the exposure of parents to chemical compounds with the subsequent impact on the child's health.
AIM: to identify gender differences in sensitization to formaldehyde among adolescents of industrial cities in relation to parental chemical exposure.
METHODS: A cross-sectional survey was conducted on a sample of 800 adolescents who were exposed to varying levels of formaldehyde inhalation. We assessed the serum levels of total immunoglobulin E (IgE) and the concentration of formaldehyde in urine among 340 participants who met the inclusion criteria. Additionally, the sensitization to formaldehyde was evaluated using the leukocytes migration inhibition test (LMIT) with this compound. Furthermore, the personalized hazard indices (HQfa) of formaldehyde exposure were calculated.
RESULTS: Urine formaldehyde concentration exceeded the reference values in 89.7% of the study participants. Elevated concentrations of IgE were more common among boys (35.4% vs. 21.9%). The highest concentrations of IgE [70.0 (4.0138.9) mU/ml] were observed in boys with HQfa 1 with the history of parental chemical exposure. It was 3.8 times as high as in girls [18.5 (1.853.4) mU/ml]. The proportion of boys with altered LMIT and HQfa 1 was greater in the group of adolescents with exposed parents (66.7%) compared to 13.3% among their counterparts with unexposed parents. The proportion of LMIT alterations in girls with HQfa 1 was 66.7% with exposed parents which is 3 times higher as high as among girls with unexposed parents (22.8%). The relative risk of sensitization to formaldehyde in boys with HQfa 1, whose parents had no pre-conceptional industrial contact with chemical compounds, was 3 times as high as in girls [OR (CI) = 3.01 (1.326.88)] under the same chemical load.
CONCLUSION: The prevalence of formaldehyde sensitization was greater among adolescent boys compared to girls. Pre-gestational parental chemical exposure was not associated with sensitization levels in regression analysis. This finding highlights the importance of considering variations in adolescent body sensitization to pollutants when developing diagnostic, preventive, and therapeutic strategies with the further going aim to reduce the burden of allergopathology and contribute to better health of the population.
Adaptation of functional systems in different generations of Caucasians in the North-East of Russia
Authors: Averyanova Inessa V. , Maksimov Arkadiy L.
Published: July 2023

BACKGROUND: A substantial body of research has focused on adaptation of the new residents of the European and Asian Far North. However, these publications fail to address the changes occurring in successive generations of native Caucasians who migrated to the regions with harsh climatic conditions.
AIM: To study functional adaptations exhibited by individuals born in the Magadan Region to various generations of Caucasians permanently living in the area.
METHODS: A total of 1632 male volunteers, all students aged 181.1 years, and of Caucasian ethnicity, participated in this study. These individuals were either migrants or residents of Russia's North-East, born within the first to third generations. We investigated anthropometric characteristics, cardiohemodynamic parameters, and gas exchange to understand the adaptive readjustments that take place within the body's functional systems.
RESULTS: Migrants and first-generation residents in the Magadan region experience constant stress and inadequate functioning of their cardiohemodynamic and energy exchange systems under extreme conditions. However, the third-generation subjects exhibited optimal performance of the cardiovascular system. Remarkably, the third-generation residents demonstrate an increased systolic volume at lower arterial pressure and lower total peripheral resistance. Furthermore, they had elevated proportion of the high frequency component and total power of the heart rhythm spectrum. This represents a new level of changed influence on the heart rhythm, as seen in the altered balance of its statistical and spectral wave characteristics. Moreover, the adaptability of the cardiovascular system to the harsh conditions of the North is reflected not only in the physiological indicators of the body but also in the integral structure of their correlations. This includes the magnitude and sign of the correlation coefficients and their significance.
CONCLUSIONS: Our main findings suggest that adaptive changes in cardiohemodynamic and gas exchange exhibited by the migrants and several generations of residents of the Far North-East of Russia are directed to minimization of the total energy expenditure in functional systems. Additionally, the parasympathetic contribution increases fostering a novel interaction between the components of autonomic nervous regulation reflected by both qualitative and quantitative alterations in the structure and patterns of correlation clusters. These findings contribute to our understanding of the physiological mechanisms behind the morphofunctional readjustments of Caucasian men in the process of adaptation to the harsh climatic conditions of the Russian North-East.
Is coracoid fracture with ac dislocation an unusual case
Authors: Makkar Dheeraj , Paila Kamik Raju
Published: July 2023

The coracoid process is a unique anatomical structure that extends anteriorly from the scapula in a hook-shaped manner, with variations in size, shape, and orientation among individuals. Although uncommon, fractures of the coracoid process may occur and can be difficult to detect on regular X-rays due to their morphology. In this case study, we report on a 46-year-old daily wage worker who presented to the emergency department with left shoulder pain and limited mobility following a traffic collision. Initial X-rays revealed only an acromioclavicular joint dislocation, but further evaluation with a CT scan confirmed a coracoid fracture with minor displacement. Despite the concurrent dislocation, we opted for conservative treatment, and the fracture had completely healed after six weeks of physical therapy. The use of specific shoulder X-ray views, such as the scapula Y or axillary view is recommended to rule out coracoid fractures, while CT scans are considered the gold standard for diagnosis. Treatment options for coracoid fractures may range from non-operative management to surgical repair, depending on the type of fracture. Our case report highlights a rare occurrence of a coracoid process fracture with acromioclavicular joint dislocation treated conservatively.
Isolation of New Strains of Microorganisms for Bio-Purification of Polluted Reservoirs of Northern Kazakhstan
Authors: Tekebayeva Zhanar , Bazarkhankyzy Aidana , Bissenova Gulmira , Temirkhanov Aslan , Sarmurzina Zinigul
Published: July 2023

This study aims to explore the potential of new microorganisms for bio-purification of polluted reservoirs in Northern Kazakhstan. Through laboratory experiments involving field collection of hydrobiological samples and screening of new strains of microorganisms, the study suggests that biological purification using organic and inorganic compounds found in polluted waters as a nutrient medium is the most effective method. This research contributes to the development of effective strategies for addressing pollution in Northern Kazakhstan's water resources and highlights the potential of using microorganisms as a tool for environmental remediation. The significance of the research lies in the fact that it proposes a solution to the issue of pollution in reservoirs in Northern Kazakhstan through the introduction of new strains of microorganisms, contributing to the development of effective strategies for improving water quality and minimizing the negative impact of pollutants on the hydrosphere.
Зарубежный опыт законодательного регулирования реализации правоохранительной функции в сфере предупреждения и пресечения административных правонарушений, связанных с потреблением наркотических средств и психотропных веществ
Authors: Ситник А.В. , Ткаченко В.В.
Published: July 2023

Распространение и пропаганда наркотиков в настоящее время находится на высоком уровне, являясь, по мнению автора, серьезной угрозой нормального и эффективного функционирования всех сфер жизнедеятельности в государстве. Наркомания не имеет границ, она разрушает общество, стимулирует рост криминогенных проявлений лиц, употребляющих наркотики, увеличивает число коррумпированных связей, поражает людей и создает другие серьезные проблемы.
Проблемы производства осмотра трупа
Authors: Суходолов . Д.С
Published: July 2023

Законодатель определяет осмотр трупа в качестве самостоятельного следственного действия, порядок его производства отражен в отдельной правовой норме - ст. 178 УПК РФ. Однако эта единственная правовая норма, посвященная осмотру трупа, а также эксгумации, недостаточно четко регламентирует порядок их производства, в виду чего на практике появляются определенные проблемы, и они требуют разрешения
Участие прокурора в рассмотрении дел о признании гражданина умершим
Authors: Филатов С.С. , Кокоха Т.С
Published: July 2023

В статье рассмотрены вопросы связанные с участием прокурора при рассмотрении судом дел о признании гражданина умершим В ней рассматривается роль прокурора в процедуре гражданского объявления о смерти, необходимость участия прокурора, особенности и проблемы, которые могут возникнуть в ходе рассмотрения дела. В статье изложены пути решения этих проблем, включая развитие законодательства и навыков прокуроров, занимающихся этим вопросом. Авторы подчеркивают важность роли прокурора в таких делах и призывают к более эффективному использованию этой роли для защиты прав граждан
THE ACTIVITIES OF DELEGATION OF THE ALBANIAN COLONY OF TURKEY IN THE PARIS PEACE CONFERENCE 1919
Authors: DRAGNEA Mihai
Published: July 2023

It was at the end of the First World War, in 1918, that a peace conference in Paris was made possible to be convened. The Peace Conference finally opened a new page in the history of international relations. Albanian people were wholly and directly focused on the proceedings of the Paris Conference from the very beginning, hoping that there they would find solutions to their problems and concerns regarding the national question. In the framework of these efforts and fully aware of the danger that threatened the country, the Albanians had to raise their voice and make known the national cause at the Conference meetings considering that, at the time, the territory of the Albanian state was occupied and the Albanians could not depend on the support of any of the triumphant post-war states. They believed that displaying their demands at the Conference convened to establish world peace would be a good opportunity to defend their rights and the injustices inflicted to them. Therefore, in addition to the delegation of the National Government from the Congress of Durrës, whose purpose was to represent the Albanian people in the Conference, there were other representatives from the Albanian diaspora. One of them was the delegation of the Albanian Colony of Turkey. The purpose of the activity of this Albanian representation was the protection of the independence of Albania, the protection of the territorial integrity of the Albanian state from the danger of a new fragmentation and the efforts for the recovery of the country. The delegates of the Albanian colonies worked together carrying out many activities in aid of the national cause, as well as propagating the right of existence of this nation through the press, meetings with various personalities or through memoranda sent to major states. Despite the difficult circumstances, the representatives of the Albanian Colony of Turkey believed in the idea that the Albanian state would rise again. Their activity marked the historical period of the Albanian people.
La IA y la ética digital: reales posibilidades y cuestionamientos para América Latina
Authors: Lotero Echeverri Gabriel Jaime
Published: July 2023

La inteligencia artificial (IA) se ha convertido en un tópico de moda. Cada organización social, económica y política tiene una visión propia sobre sus alcances y utilidades. En ocasiones colinda con la fascinación y en otras con el temor. Realmente la conocemos mal pues es una innovación que llega y se expande por el ámbito social, integrándose de manera casi imperceptible en los marcos de vida cotidiana más diversos. El ChatGTP la llevó a la superficie y las posturas sobre la IA se encuentran polarizadas. De ahí la importancia de conocer a fondo el contexto desde el cuál surge. Será fundamental, en consecuencia, analizar además de sus funciones y alcances, las preguntas pertinentes que debemos formularnos para comprender su naturaleza y la manera como nos puede llegar a ayudar.
Structural Properties, Photoluminescence, and Judd-Ofelt Parameters of Eu3+- Doped CoNb2O6 Phosphor
Authors: İLHAN Mustafa , GÜLERYÜZ Lütfiye Feray , EKMEKCİ Mete Kaan
Published: July 2023

Trivalent Eu-activated CoNb2O6 phosphors were fabricated using the molten salt method, which provides enhanced homogeneity and low sintering temperature. The ceramic samples were examined by spectral and structural analyses. In X-ray diffractions, the single phase of orthorhombic columbite type CoNb2O6 structure was obtained for 0.5-10 mol% Eu3+ doping concentrations, while a two theta peak shift towards the smaller angles occurred. SEM examinations show an irregular morphology and sub-micron grain sizes. In photoluminescence (PL) spectra, the phosphors showed typical Eu3+ emissions with the 5F0 → 7FJ (J=0, 1, 2, 3, 4) transitions, and high emission peaks were observed at the 5D0 → 7F2 transition. The photoluminescence of CoNb2O6:Eu3+ decreased over 5 mol% because of the concentration quenching. The energy transfer mechanism and critical distance of the phosphor are the dipole-dipole (d–d) interaction, and 15.70 Å, respectively. The spectral features of the phosphors were assessed by calculating the Judd-Ofelt intensity parameters (Ω2, Ω4) from the PL emission spectrum. The low Ω2 parameter values or/and the Ω4>Ω2 trend for CoNb2O6:Eu3+ phosphors were related to the less covalent or more ionic character of the Eu3+–O2˗ bond and the high local symmetry of the Eu3+ sites, while the high Ω4 parameter values may be ascribed to the decrease in the electron density in the ligands.