bluuebunny/crossref_metadata_2025 huggingface dataset:
Cocoa supplementation reduces amyloid-beta1–42 (Aβ1–42) induced deficits in a transgenic C. elegans
Authors: Munasinghe Mihiri , Almotayri Abdullah , Kolivas Despina , Thomas Jency , Heydarian Deniz , Jois Markandeya
Published: May 2021

BACKGROUND:

Cocoa, a significant contributor of polyphenols to the western diet has been shown to be effective against Aβ induced toxicity in vitro. However, the effects of long-term cocoa supplementation on Aβ induced behavioural deficits, particularly on the short-term memory loss observed in human AD are not well defined.

OBJECTIVE:

This study characterized the phenotype of a pan-neuronal Aβ expressing C. elegans strain and investigated the effects of long-term cocoa supplementation on Aβ induced behavioural deficits including short-term memory loss and lifespan.

METHODS:

Cocoa powder was supplemented to the E. coli OP50 diet of C. elegans starting from L1 stage until they die. Neuronally controlled processes including locomotion, learning and memory were studied at different stages of the lifespan. In addition, lifespan was evaluated with different cocoa doses. Aβ fibril levels were determined with Thioflavin T.

RESULTS:

Aβ expressing worms showed a reduced growth, a reduced maximum speed at old age, short-term memory deficits at middle age and a reduced lifespan. Cocoa-supplementation reversed the deficits in growth, maximum speed, short-term memory loss and lifespan to reach similar levels to control counterparts while reducing the Aβ fibril levels.

CONCLUSIONS:

Long-term cocoa supplementation seemed to improve Aβ induced deficits in C. elegans.
THE GENERAL PRINCIPLES OF THE COMPLEX PROCESS OF THE RESTORATION-RECONSTRUCTIVE TRANSFORMATIONS OF THE HISTORICAL CENTERS OF SMALL TOWNS
Authors: Leshchenko Nellia
Published: May 2021

The article gives the definition of «restoration-reconstructive transformation» (RRT). Four interconnected systemic levels of the complex process of restoration- reconstructive transformations of the historical centers of small towns have been identified, namely: urban, volumetric, functional and socio-economic. The general principles of the complex process of RRT of the historical centers of small towns are formulated. These are the principles of: «cumulative development» (the accumulation of positive properties that together contribute to its qualitative change, a combination of «traditions» and «innovations»); «contextual addition» (introduction of the necessary new buildings and spaces according to the formed context); «attractive spatial disclosure» (increasing the attractiveness of the historical center) and «multi-comfort» (providing a qualitatively different duration of stay of different people in the historical center). The principles are recommended for the implementation of qualitative changes in historic centers at all defined four systemic levels. They are universal for the historical environment, of any degree of value and destruction, when carrying out the restoration-reconstructive transformations using preserving and restoring, as well as renewing and transforming methods, to improve its quality and transition to a multi-comfortable one. The principle of «cumulative development» is highlighted as the main one in the implementation of the restoration-reconstructive transformations of the historical city centers. The conditional correspondence of the general principles and methods of RRT was determined. For the principles of «cumulative development», «attractive spatial disclosure» and «multi-comfort» – all preserving, restoring, renewing and transforming RRT methods of urban level and the corresponding ones from the volumetric and functional levels, depending on the degree of value and destruction of the historical environment. For the principle of «contextual addition» – restoring, renewing and transforming RRT methods of urban level (regeneration, revalorization, renewal, revitalization, transformation, renovation) with the corresponding methods of volumetric and functional levels.
MULTICRITERIA ANALYSIS AS A METHOD OF CHOICE JUSTIFICATION FOR ENGINEERING AND PLANNING DECISIONS OF CITY HIGHWAYS’ INTERSECTIONS
Authors: Osetrin Mykola , Tarasiuk Volodymyr , Bespalov Dmytro , Bespalov Dmytro , Myroshnychenko Оxana
Published: May 2021

This article aims to familiarize the reader with multi-criteria analysis as one of the methods of choice justification of engineering design solutions for urban highways intersections. This method is widely used abroad, as it allows to compare different quantitative and qualitative indicators with different vectors of "positive decision" (maximum or minimum).

Multiple criteria decision analysis – MCDA, as fact-based quantitative method is more appropriate way to evaluate several indicators simultaneously for each of planning decisions – opposed to more popular in Ukraine “expert evaluation”. In transport planning, type of multicriteria analysis method, which should be used for evaluation of urban highways’ intersections planning decisions, depends on specific conditions and chosen scales of evaluations.

Article includes description of one of MCDA’s types: TOPSIS (Technique for Order of Preference by Similarity to Ideal Solution) and illustrates algorithm of its calculation. As an example, four variants of planning decisions of right-bank approaches to the Podilsko-Voskresensky bridge intersection in the city of Kyiv are analyzed. As a result, a rating of design scenarios of intersection planning solutions according to the TOPSIS method was obtained.
NATIONAL SYMBOLS AS THE ELEMENT OF IDENTITY IN ARCHITECTURE OF DIPLOMATIC LEGATIONS
Authors: Tymovchak Iryna
Published: May 2021

The article determines the peculiarities of introducing national symbols into the architecture of modern diplomatic legations with the aim of reflecting identity and uniqueness of different states of the world. In the context of globalization, multiculturalism, development of supranational institutions, and terrorist threats, the problem related to the means of expressing national identity in the architecture of diplomatic legations, which are the representation platform for each state worldwide, has appeared. The interpretation conciseness and artistic rethinking of national symbols is the major tool applied by architects and building constructors of diplomatic legations of the XXI century. From this perspective, it is particularly important to understand that, on the one hand, the mentioned architectural objects should be treated as symbols of state and nation, but on the other hand, should go in line with local traditions of building construction and architecture, cooperation with local culture, and surrounding environment of host country.

For the sake of self-identification, each state worldwide uses national symbols that become an integral part of their international image brand. During the course of research, the following types of national state symbols have been distinguished:

The main:

Secondary:

-         flag;

-         coat of arms.

 

-       fauna and flora;

-       peculiarities of natural resources;

-       national identity and social order;

-       architectural style, fine arts, ornamentation;

-         symbols of religion and state regalia;

-         ideology and policy of the state.

Official symbols (state symbols) are determined and enshrined at the constitutional and legal level. They are being created during the process of state establishment. Informal symbols are not always enshrined in law and are not mandatory to be used. However, namely these symbols are the full-fledged reflection of uniqueness of nature, culture, religion, history, traditions, politics, and ideology of nation and state.

Embassy is the diplomatic legation of the highest rank by means of which any state conducts its official activity abroad. The analysis of architectural composition, dimensional and spatial structure, artistic and aesthetic decisions of exterior and interior elements of embassy buildings has enabled the possibility of demonstrating different methods and approaches to solving the problems of using and providing artistic interpretation of national symbols as the element of state identity representation.
PRACTICAL STEPS FOR RENOVATING THE ARCHITECTURAL AND PLANNING ORGANIZATION OF PUBLIC LIBRARY BUILDINGS
Authors: Urenev Valery , Rumilets Tanya , Antonenko Nadiia
Published: May 2021

The article considers the current process of implementing the concept of four spaces in the Ukrainian libraries, which was developed by experts from the Center for Cultural Policy Studies of the Royal School of Library and Information Sciences at the University of Copenhagen (2006) in terms of architectural and planning reorganization of public libraries. The main results of the project-experimental work, which included the development of project documentation for the pilot project of the renovation of the public library in Odesa and a comparison of the stages of work with the information presented in the manual "Four library spaces: innovative model" (2020). The principles on which any project of renovation of library premises should be based were revealed: 1) libraries are places of professional and social development; 2) libraries should become accessible; 3) libraries are inclusive spaces; 4) libraries should be secure; 5) libraries should become convenient. It was found that the manual has a number of shortcomings and does not provide librarians with enough information to reorganize library spaces without the involvement of an architect, namely: 1) the manual does not pay enough attention to the development of universal examples of architectural and planning solutions; 2) there are no recommendations for providing transformative spaces with structures and furniture; 3) there is no emphasis on the need to implement the principles of universal design and barrier-free library spaces; 4) there are no recommendations for improving the insolation of the premises and the lighting design of individual spaces. A plan of alternative measures that need to be worked out to ensure the rapid transformation of libraries is proposed. An effective methodology should be based on the principles of universality of spaces and combinatorics of room equipment, as well as be flexible and able to scale both quantitatively and qualitatively.
Evidence from FDA Compliance Check Inspections on the Effectiveness of Retail Access Controls on Tobacco Purchases
Authors: Chen Tengjiao , Zion Adam , Joselow Jonah , Kasmer Parker
Published: May 2021

This study analyzes data from FDA’s compliance check inspections of tobacco product retailers to assess the effectiveness of Retail Access Control Standards™ (RACS). RACS is a standards-based technology solution at the point-of-sale that automatically prompts electronic ID scanning to verify the age of the purchaser of electronic nicotine delivery systems (ENDS) and imposes automated product-quantity purchase limits (to reduce the potential for social sourcing). Supported by JUUL Labs, Inc., RACS is being adopted for the sale of JUUL products, but has not uniformly been implemented for other tobacco products. This study assesses the incidence of FDA compliance check inspection failures across tobacco-product types at a regional chain of convenience stores that implemented RACS, and compares it to those observed at similar retail locations without RACS. At the chain that implemented RACS, in the 8 months after RACS was installed, there were a total of 10 inspection failures, of which none were ENDS-related. At the comparator sites, 28% of failures were ENDS-related. These findings provide real-world evidence that an automated, technologically-based solution for age-verification at the point-of-sale, such as RACS, may effectively restrict underage access and thus contribute to reducing underage use. This points to the potential benefit of adopting similar approaches across all tobacco products and potentially other age-restricted products.

KEYWORDS:    Retail Access Control Standards (RACS); FDA compliance check inspections; age verification; youth prevention; electronic nicotine delivery system (ENDS); enhanced access controls; tobacco.
Surface lipids of Kalanhoe as a material for nanoparticles preparation
Authors:   Ukrainian State University of Chemical Technology, Berzenina O.V. , Kytova D.E. ,   Ukrainian State University of Chemical Technology, Shtemenko A.V. ,   Ukrainian State University of Chemical Technology, Shtemenko N.I. ,   Ukrainian State University of Chemical Technology
Published: May 2021

The purpose of the investigation was to elaborate the methods of extraction of surface lipids from Kalanchoe Degremona plants and preparation of solid lipid nanoparticles containing a dirhenium(III) cluster compound. The procedure of growing plants and increasing the quantity of surface lipids by means of adaptation biochemistry to toxicants was used in this work. Data on the quantities of extracts, IR-spectra, and GC-MS-data of hydrocarbons and oxocompounds of surface lipids obtained were presented. An increase in the total number of surface lipids and an insignificant change in heterogeneity under the influence of monochlorobenzene exposition were shown. The absence of differences in the ratio of the intensity of the characteristic bands in the FTIR spectra allowed concluding that the toxicant did not affect the qualitative composition of the surface lipids. The nanoparticles (with a size of 14540 nm) with high encapsulation efficiency were prepared, these nanoparticles containing the dirhenium(III) cluster compound that previously showed a cytostatic action in experiments in vivo.
Dehydration of isopropyl alcohol with activated carbon functionalized with Br- and S-containing reagents
Authors:   Taras Shevchenko National University of Kyiv, Grishchenko L.M. , Zaderko A.N. , Tsapyuk G.G. , IMatushko I.P. , Yatsymyrskyi A.V. , Mischanchuk O.V. ,   Chuiko Institute of Surface Chemistry of the National Academy of Sciences of Ukraine
Published: May 2021

Bromination of activated carbon GSGD was performed and active bromine-containing precursors were obtained, in which bromine is capable of being replaced by sulfur-containing functional groups. Bromination with liquid bromine and a solution of bromine in potassium bromide at room temperature leads to the introduction of 0.44–0.45 mmol g–1 of bromine into the surface layer of activated carbon. The treatment of brominated samples with sulfur-containing reagents with subsequent oxidation allows obtaining carbon samples that are catalytically active in the dehydration reaction of isopropyl alcohol in a gas phase. The temperature of complete conversion of isopropyl alcohol to propylene is a measure of catalytic activity. The concentration of sulfogroups in the prepared samples is up to 0.3 mol g–1. Thermogravimetry and thermoprogrammed desorption with mass spectrometric registration of products were used to study the thermal stability of modified activated carbon samples. The influence of the nature of brominating reagents, hydrolysis conditions and oxidation conditions on the structure, surface concentration of grafted S-containing groups and catalytic properties of the obtained materials was studied. Pre-bromination leads to an increase in the catalytic activity of activated carbon modified with sulfur-containing groups and the temperature of complete conversion of isopropyl alcohol to propylene decreases up to 400C depending on the concentration of sulfogroups.
Using the Irrigation Controller for a Better Lawn on Less Water
Authors: Tichenor Jack , Dukes Michael D. , Trenholm Laurie E.
Published: May 2021

Would you like to have an attractive, healthy lawn that uses less water, costs less to maintain and may even reduce fertilizer and pesticide use? This may sound too good to be true. The right amount of water at the right time can make it happen for you. This document is Fact Sheet ENH978, one of a series of the Environmental Horticulture department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Original publication date: December 23, 2003. Reviewed November 2004.
Preventing Foodborne Illness: Bacillus cereus and Bacillus anthracis
Authors: Schneider Keith R. , Parish Mickey E. , Goodrich Renée M. , Cookingham Taylor
Published: May 2021

Bacillus species are Gram positive, aerobic heterotrophs, ubiquitous bacteria, characterized by their ability to form resistant spore coats. There are about 48 known species in the genus Bacillus but only B. anthracis and B. cereus are associated with human disease. Bacillus species are mesophilic bacteria that produce heat-resistant endosopores with a growth range of 10°C to 48°C, with optimal growth at 28°C to 35°C. In addition, they can grow in a broad pH range of 4.9 to 9.3. This document is FSHN04-05, one of a series of the Food Science and Human Nutrition Department discussing common foodborne pathogens of interest to food handlers, processors and retailers; Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Date published: November 2004.
Healthy Eating for Elders: Sixteen Savory Snacks
Authors: Hillan Jennifer B.
Published: May 2021

Here are some snack ideas that are not only easy to prepare, they are healthy too! Keep some of these choices handy for the next time you have the snacking urge. This is document FCS 8697-ENG, one in a series of the Department of Family, Youth and Community Sciences, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611. Publication date: February 2005.
UF/IFAS Strawberries beyond the USA: A Success Story from Egypt
Authors: EL-Borai Fahiem , Whitaker Vance M.
Published: May 2021

Currently, Florida strawberry varieties are grown in over 70 countries spread across six continents. The main objective of this Extension publication is to communicate the benefits of licensing UF/IFAS strawberries outside of the USA, with a special focus on Egypt. The target audience of this new 6-page publication of the UF/IFAS Horticultural Sciences Department includes those involved in the strawberry industry as well as the general public. Written by Fahiem EL-Borai and Vance M. Whitaker.https://edis.ifas.ufl.edu/hs1411
Eggplant Pest Management Strategic Plan (PMSP)
Authors: Mossler Mark A. , Nesheim Olaf Norman
Published: May 2021

This circular describes discussions held between Florida eggplant producing stakeholders and pest management professionals in June 2004. Specific actions for research, education, and regulation are presented in the document.
Anurans of the Everglades Agricultural Area
Authors: Casler Michelle L. , Bear Wendy M. , Pearlstine Elise V. , Mazzotti Frank J.
Published: May 2021

This is a guide to frogs and toads in south Florida. This is document Cir 1463, one of a series in the Department of Wildlife Ecology and Conservation, University of Florida. Published December 2004. 

Cir 1463/UW210: Anurans of the Everglades Agricultural Area (ufl.edu)
CORRELATION OF HB1AC WITH LIPID PROFILE IN NEWLY DIAGNOSED TYPE 2 DM PATIENTS
Authors: Chain Sukh , Saran Mansa Ram
Published: May 2021

Background: HbA1c is a main indicator for mean blood glucose level. Dyslipidemia especially high LDL, is common in diabetes mellitus and is strongly associated with poor glycemic control.

Method: A retrospective study was carried out to determine the LDL levels in newly diagnosed type 2 diabetics. A total of 100 newly diagnosed type 2 diabetics were enrolled in our study.

Result: In our study, maximum patients (54.00%) were from 46-60 years followed by, 25.00% patients who were more than 60 years and 21.00% patients were less than 45 years of age. HbA1c is significantly directly proportional to LDL level

Conclusion: It was concluded from the results of this study that type 2 diabetic patients are more prone to dyslipidemia. In newly diagnosed type type 2 diabetes mellitus, high LDL levels were found in patients with high HbA1C levels. 

Keywords: Type 2 diabetes mellitus, HbA1c, LDL
A Covid-19-világjárvány hatása a telemedicina védelmi besorolására
Authors: Helyes Marcell , Fejes Zsolt
Published: May 2021

A szerzők célja, hogy rávilágítsanak egy jelenleg még határterületi megjelenéssel jellemezhető, de a koronavírus-világjárvány során kiemelt szerepet elnyerő és egyreinkább önálló domén formájában megjelenő rendszer, a telemedicina jelentős térnyerésére. A betegség természetéből adódó korlátozások és az ezzel egyidőben a lakosság részéről fokozódó egészségügyi ellátási igény együttesen emelte a telemedicinát az egészségügyi ellátás fókuszába. Ennek következményeként jelent meg hazánkban a jogalkotók részéről azon törvényi módosítás, amely a telemedicina működését mind szabályozás, mind finanszírozási oldalról egyaránt támogatta.A szerzők a tanulmányban arra keresik a választ, hogy a konvencionális egészségügy mellett a telemedicinális rendszer felfogható-e mint önálló entitás, és ennek jogána közeljövőben alkalmassá válik-e majd arra, hogy a törvényi szabályozás szerint a létfontosságú rendszeri besorolással járó fokozott védelmi prioritást élvezzen.
Az egészségügyi szűrés kockázatelemzésen alapuló új modellje
Authors: Szepesváry Zsolt , Pelcz Dominika
Published: May 2021

A Magyarországon használatos szűrővizsgálati rendszer nem egységes elvek mentén épül fel a katonai és a polgári egészségügyben. Nincsen csak evidenciaalapú vagykockázatbecslésre hagyatkozó módszer. Egyik szűrési rendszer sem vizsgálta meg, hogy mely betegségek szűrendők az egymáshoz képesti előfordulásuk függvényében. A jelen szűrővizsgálati protokollban szereplő betegségek kimutatása bizonyítottan szükséges, de nem történt vizsgálat arra nézve, hogy biztosan ezek a legfontosabb szűrendő kórképek, illetve a lista frissítésére sincsenek irányelvek. Létrehoztunk egy modellt, amely alapján összehasonlíthatóak a szűrendő betegségek az előfordulási kockázatuk alapján. A modell segítséget nyújthat az egészségügyi rendszerek üzemeltetésében és a szűrővizsgálatok tervezésében.
Új személyi légideszantejtőernyő-típus rendszerbe állítása előtt a Magyar Honvédség V. rész
Authors: Szaniszló Zsolt
Published: May 2021

Többrészes tanulmányom a Magyar Honvédség (MH) új személyi légideszantejtőernyő-rendszerrel történő ellátásának szükségességére hívja fel a figyelmet, és természetesen javaslatot tesz a beszerzésre irányuló kezdeti lépések megtételére. A tanulmány korábbi részeiben napjaink legelterjedtebben alkalmazott konvencionális személyi légideszantejtőernyő-rendszereit mutattam be, és elemeztem a főés a tartalékejtőernyő-, illetve a biztonságinyitóműszer-típusokat. A tanulmány ötödik, egyben befejező része számos hadseregben alkalmazott modern, de ugyanakkor még hagyományos rendszerű személyi légideszantejtőernyő- rendszerekhez rögzíthető személyi felszereléseket vizsgálja meg, amelyekkel az MH légideszantosai, mint lehetséges alkalmazók, ugrásaikat a jövőben biztonságosan végrehajthatják.
A kibertér fejlődése (második rész)
Authors: Kralovánszky Kristóf
Published: May 2021

Az állami akaratérvényesítés eszközei között egyre hangsúlyosabb szerepet kapnak a kiberműveletek. Alkalmazásuk sokkal komolyabb körültekintést igényel,mint a hagyományos tartományokban végzett műveletek, mivel a megtámadott infrastruktúra nem kellően felmért interdependenciái hatalmas járulékos károkat okozhatnak a támadónak is. Jelen tanulmány ennek bizonyos kockázatait és összefüggéseit vizsgálja.
UPAYA PENINGKATAN HASIL BELAJAR MATEMATIKA SISWA KELAS XI IPS 1 SMA NEGERI 3 TEBING TINGGI DENGAN MENERAPKAN MODEL PROBLEM BASED LEARNING
Authors: Balad Miftahul , Maimunah . , Nur Siregar Syarifah
Published: May 2021

Tujuan penelitian ini adalah untuk meningkatkan hasil belajar matematika siswa dengan menerapkan model Problem Based Learning. Bentuk penelitian ini adalah penelitian tindakan kelas yang terdiri dari dua siklus. Subjek penelitian ini adalah siswa kelas XI IPS 1 SMA Negeri 3 Tebing Tinggi yang berjumlah 16 orang dengan tingkat kemampuan akademik heterogen yaitu digolongkan dalam kategori tinggi, sedang dan rendah. Instrumen penelitian terdiri dari instrumen pengumpulan data berupa lembar pengamatan dan lembar tes hasil belajar serta perangkat pembelajaran berupa Silabus dan Rencana Pelaksanaan Pembelajaran yang sudah dilengkapi dengan Lembar Aktivitas Siswa. Teknik pengumpulan data pada penelitian ini adalah teknik pengamatan dan teknik tes. Lembar pengamatan dianalisis secara deskriptif naratif, sedangkan tes hasil belajar dianalisis secara statistik deskriptif. Berdasarkan analisis data kualitatif disimpulkan bahwa terjadi perbaikan proses pembelajaran setelah penerapan model Problem Based Learning. Pada analisis data kuantitatif, persentase siswa yang mencapai KKM kompetensi pengetahuan pada skor dasar yaitu 31,25% (5 siswa), meningkat menjadi 43,75% (7 siswa) pada siklus pertama dan meningkat menjadi 62,5% (10 siswa) pada siklus kedua. Pada kompetensi keterampilan, persentase siswa yang mencapai KKM pada siklus I yaitu 43,75% (7 siswa) meningkat menjadi 81,5% (13 siswa) pada siklus kedua. Berdasarkan analisis penelitian tersebut dapat disimpulkan bahwa penerapan model Problem Based Learning dapat meningkatkan hasil belajar matematika siswa kelas XI IPS 1 SMA Negeri 3 Tebing Tinggi semester ganjil tahun pelajaran 2019/2020Kata kunci: : Hasil Belajar Matematika, Model Problem Based Learning, Penelitian Tindakan Kelas
PERIOD USE OF LANGUAGE TERMS PANDEMY COVID-19
Authors: Widodo Widodo , Syamsu Muhajir , Masduki Uki
Published: May 2021

A word or phrase (a combination of words) that is used as a name or symbol and which accurately expresses the meaning of a concept, process, state, or characteristic that is unique in a particular field such as science, technology, art and so on. This study aims to describe the characteristic patterns of various linguistic terms during the Covid-19 pandemic. This study uses a qualitative descriptive approach in which this study does not use numbers but in the form of words to describe the results of the study. The technique used in this study is to use observation and data collection techniques. The results showed that there were 36 data on the pattern of the Covid-19 language terms which were analyzed and then classified into 14 data in the form of English, 8 data in the form of synonyms, 3 data in the form of English abbreviations, 4 data in the form of Indonesian abbreviations and 6 data in acronym form. The implication of this research is that many people use foreign terms such as corona virus, social distancing, physical distancing, and new normal. Therefore, it is necessary for the role of every citizen, government and media during a pandemic to use the Indonesian language in order to protect the sovereignty of the nation.Keywords: language terms, Covid-19
Influence of vitamin-mineral supplement on protein metabolism in rabbits’ organisms
Authors: Fedorchenko M.
Published: May 2021

The purpose of the study is to study the influence of different vitamin-mineral supplement “Tekro” doses on biochemical parameters in blood plasma and liver of rabbits of New Zealand breed. The research methodology is based on research according to generally accepted research methods. Biochemical parameters were studied in rabbits’ organisms at 45, 60, 75 and 90 days of rearing with feeding of different doses of vitamin-mineral supplement “Tekro”, namely 3 %, 3.5 %, 4 %. The academic novelty is that nowadays the problem of the effect of different vitamin-mineral supplement “Tekro” doses on biochemical parameters in the blood and liver of rabbits has not been studied. Analyzing the indicators of the total protein content in the blood plasma of rabbits of the experimental groups and the control one for 90 days, it was noted that there was no significant difference in the indicators. In the liver of rabbits of the age from 45 to 90 days there was a tendency to increase the protein content due to the effects on the body of various doses of vitamin and mineral supplement “Tekro”. It has been established the positive effect of vitamin-mineral supplement “Tekro” on ALT activity of rabbits in experimental groups. At the age of 75 days, significantly higher ALT activity was recorded in rabbits of the 3rd experimental group by 35.8 % compared to animals in the control group.
Diagnostic value of echocardiographic indices of left atrial and ventricular morphology in dogs with myxomatous mitral valve disease (MMVD)
Authors: Trofimiak R. M. , Slivinska L. G.
Published: May 2021

Myxomatous mitral valve disease (MMVD) is one of the most common acquired diseases of the cardiovascular system of genetic etiology in small breed dogs. A long asymptomatic course characterizes the disease. Presently, the main diagnostic technique for heart diseases is echocardiography. This study evaluates individual echocardiographic indices of the left atrial and ventricular morphology with the determination of the diagnostic value of each of them in predicting the course of the disease. The study was conducted in a private veterinary hospital “Eurovet” and on the basis of the clinic of the Department of internal animal diseases and clinical diagnostics of Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnology Lviv during 2018–2019. The objects consisted of 46 dogs with a confirmed diagnosis of myxomatous mitral valve disease according to the recommendations of the American College of Veterinary Internal Medicine (ACVIM) and no signs of comorbidities. During the study, three experimental groups of animals were formed according to the clinical and functional status characteristic of each stage of MMVD development – B1, B2, C. According to the results, all experimental dogs showed changes in the mitral apparatus in the form of thickening of the anterior and posterior cusps, mitral valve (MV) prolapse into the left atrial (LA) cavity and regurgitation (MR), the severity of which increased with the stage of the disease (from 20 % to 60 %). In 44.4 % of animals in group B2, thickening of the left ventricular walls was diagnosed in diastole and in 22.2 % in systole. Instead, these values increase to 46.1 % and 53.8 % in group C, respectively. However, the degree of hypertrophy is disproportionate. With the development of the disease, we detect its decrease from 0.64 ± 0.03 (group B1) to 0.50 ± 0.04 (group B2) and 0.51 ± 0.03 (group C) also we observed an increase in LVEDD/2 from 1.30 ± 0.05 cm (group B1) to 1.46 ± 0.12 cm (group B2) and 1.54 ± 0.13 cm (group C). The value of nLVEDD in B1 was 1.36 times (P < 0.001) lower compared to B2 and C. Higher values of this parameter were found in 23.1 % of dogs in group C compared to the maximum value of B2. As MV insufficiency progresses, the LA/Ao index increases slightly (1.08 times) in B2, followed by an increase in C (1.38 times, P < 0.001). At the same time, we diagnose an increase (P < 0.05) in PV/PA by 1.18 times in B2 and 1.46 times (P < 0.001) in C. Thus, an increase in the severity of mitral regurgitation, a rapid increase in nLVEDD, the dynamics of the decrease in the degree of hypertrophy h/R, as well as an increase in LA/AO, PV/PA indices are predictors of unfavorable prognosis of myxomatous degeneration of the mitral valve in dogs.
Use of plant-derived drugs in the prevention and treatment of dairy cow mastitis
Authors: Xu Ping , Fotina Hanna , Fotina Tetiana , Wang Sanhu
Published: May 2021

Dairy cow mastitis is one of most seriously diseases affecting dairy herds.  The prevention and treatment of this pathology is especially done through antimicrobials, but the increasing antimicrobial resistance of pathogens to this disease may affect the efficiency of conventional drugs. Plant extracts are increasingly being valued by livestock producers because of their wide sources, low toxic and side effects, and high environmental affinity. Thereby, a lot of research has been conducted on the control of dairy cow mastitis by plant-derived drugs in recent years. This review summarizes the current of the plant types, main active ingredients, and the mechanism of action of plant extracts for preventing and treating dairy cow mastitis. Finally, a review was carried out to prospect the future development of plant extracts in the treatment of dairy cow mastitis.
Die Rolle des Schlichters im Sonder Zivilgericht am 4. Sondern Sozialgericht von Macapá-AP, Amazônia, Brasilien
Authors: Neto Dalk Dias Salomão , Sousa Nicole Moreira Faria , Dendasck Carla Viana , Fecury Amanda Alves , Oliveira Euzébio de , Dias Claudio Alberto Gellis de Mattos
Published: May 2021

Aufgrund zahlreicher sozialer Probleme wurde Gerechtigkeit von der Gesellschaft mehr gefordert. Es bestand dringender Bedarf an einem neuen Paradigma, mit der Schaffung von Sonderverfahren, die auf Vermittlung basieren, als alternatives Mittel zur Konfliktlösung als Teillösung. Die Sondergerichte haben sich seit ihrer Gründung durch das Gesetz 9.099/95, das sich angesichts der großen Forderungen der Klagen als äußerst wichtig für die Neuordnung der Justiz erwies, stark weiterentwickelt. Ziel dieser Arbeit war es, die Rolle des Schlichters im speziellen virtuellen Zivilgericht in der 4avara des Sonderzivilgerichts von Macapá AP, Amazônia, Brasilien zu analysieren. Es wird der Schluss gezogen, dass die Sonderjustiz von der Umsetzung über das Gesetz 9.099/95 bis zum Aufbau ihrer Grundsätze wie Verfahrensschnelligkeit, Informalität und, was auf die Verwirklichung eines schnelleren und effizienteren Prozesses hindeutet, eine historische Entwicklung war. PROJUD und TUCUJURIS durch die Computerisierung der Sondergerichte scheinen bei der Modernisierung des Prozesses wichtig zu sein, sie einfacher, schneller und für alle zugänglich zu machen und damit den technologischen Trends der Welt zu folgen. Sondergerichte als Ganzes sollten versuchen, immer mehr in Schlichter und Schlichtungsklagen zu investieren, wie etwa staatliche und nationale Vermittlungswochen, denn so wird es eine große Möglichkeit geben, dass Fälle in der Justiz stärker fließen.
El rol del conciliador en el Juzgado Especial Civil Especial del Cuarto Juzgado Especial Civil de Macapá-AP, Amazônia, Brasil
Authors: Neto Dalk Dias Salomão , Sousa Nicole Moreira Faria , Dendasck Carla Viana , Fecury Amanda Alves , Oliveira Euzébio de , Dias Claudio Alberto Gellis de Mattos
Published: May 2021

Debido a numerosos problemas sociales, la sociedad comenzó a pedir más justicia. Era urgente un nuevo paradigma, con la creación de cortes especiales, basados en la conciliación, como medio alternativo de resolución de conflictos como solución parcial. Los tribunales especiales han evolucionado mucho desde su creación, a través de la ley 9.099/95, que resultó extremadamente importante para la reorganización de la justicia, frente a las grandes demandas de los juicios. El objetivo de este trabajo era analizar el papel del conciliador en el tribunal civil virtual especial en el 4avara de la corte civil especial de Macapá AP, Amazônia, Brasil. Se concluye que hubo una evolución histórica de los jueces especiales, desde su aplicación a través de la Ley 9.099/95 hasta la construcción de sus principios como la rapidez procesal, la informalidad y, todo apuntando a la realización de un proceso más rápido y eficiente. PROJUD y TUCUJURIS computarizando las canchas especiales parecen ser importantes en la modernización del proceso, haciéndolos más simples, rápidos y accesibles para todos y siguiendo así las tendencias tecnológicas del mundo. Los tribunales especiales en su conjunto deben tratar de invertir cada vez más en conciliadores y acciones encaminadas a la conciliación, como las semanas de conciliación estatales y nacionales, porque por lo tanto, habrá una gran posibilidad de que los casos en el poder judicial ganen mayor fluidez.
Strategy to strengthen the traditional milpa family production systems
Authors: Uzcanga Pérez Nelda Guadalupe , Cano-González Alejandro , Cadena-Iñiguez Pedro
Published: May 2021

Objective: To characterize family production units (FPUs) to identify critical points for their activities and propose intervention strategies for them.Design/methodology/approach: The research took place at Yaxcabá municipality, state of Yucatán, Mexico. It is descriptive and its information obtained through 1) a questionnaire in a mobile application compatible with the Android operating system, structured by modules: producer data, FPU characteristics, crops, infrastructure, machinery, equipment, and marketing. The sample size was randomized with replacement, under the maximum variance condition, 2) assessment visits to the farmer’s plots and 3) participatory community diagnosis workshops.Results: The traditional milpa system was oriented to the cultivation of corn, beans and squash of creole origin, for consumption by the FPUs with minimum technologies usage. Through apiculture, producers obtain an economic resource to finance other activities, including those of the milpa. It is, therefore, necessary to strengthen their productivecapacities of this activity with a chain approach, for the diversification of their products and derivatives of their hives that allow their income to increase.Limitations on study/implications: The proposals and intervention strategies may only be applied to the production system in the evaluated area.Findings/conclusions: The strategies for the traditional milpa production should be oriented to food security, biodiversity preservation and the nutritional health of their related population. Apuculture strategies should aim to include producers in the value chain.
The melliferous flora of Veracruz, Mexico
Authors: Real Luna Natalia , Alcántara Salinas Graciela , Rivera Hernández Jaime Ernesto , Zalazar Marcial Edgardo , Pérez-Sato Juan Antonio
Published: May 2021

Objective: To contribute to the knowledge of the situation of the melliferous flora in Veracruz for pollinators and to communicate it for the benefit of beekeepers and stingless beekeepers, as well as to develop comprehensive strategies with these activities.
Design/Methodology/Approach: The information was obtained through a bibliographic review in reference databases such as Scopus, Web of Science Group, Academic Google, Elsevier and Springer Link, using the following keywords: flora, bees, pollinators, honey, pollen.
Results: 63 families were recorded, with 176 genera and 216 species of melliferous flora, finding that the largest number of species are found in the Fabaceae family (20%) and Asteraceae (16.55%). There were also 44 crops with 22 families.
Study Limitations/Implications: There were no limitations in conducting this study.
Findings/Conclusions: The greatest diversity of melliferous flora species is seen in wild plants, and strategies need to be implemented for their protection and multiplication. For these actions, various actors must be involved at different levels of government, educational and private institutions, civil society, farmers, beekeepers, and stingless beekeeping. Conservation actions include the use of melliferous plants in gardens and their protection in crops, sites surrounding crops and on edges. It is necessary to preserve natural landscapes and restore damaged ones, as well as to lead favorable practices in pollinator-dependent crops.
Cerium (Ce) Affects the Phenological Cycle and the Quality of Tulip (Tulipa gesneriana L.)
Authors: Gómez-Navor Tsujmejy , Gómez-Merino Fernando C. , Alcántar-González Gabriel , Fernández-Pavía Y. Leticia , Trejo-Téllez Libia I.
Published: May 2021

Objective: To study the effect of Ce applied in a nutrient solution during the productive cycle, on the duration of the phases of the phenological cycle of tulip cv. Jan van Nes.
Design/Methodology/Approach: Commercial bulbs (caliber 12+) were planted under shade cloth conditions during the autumn-winter period. The levels of Ce used were 5, 15 and 15 µM from CeCl3 7H2O; Ce was applied in the nutrient solution from the first day of the sowing, apart from the control without its application.
Results: The different concentrations of Ce bulb sprouting. The low concentration of Ce (5 ?M) promoted the early formation of floral buds and their coloration. Hence, the application of 5 ?M Ce advances flowering of the tulip without exhibiting changes in the period of time to reach senescence. When 25 ?M Ce were applied, the opposite effects were observed. The duration of the flower was not significantly affected by the treatments.
Study Limitations/Implications: This study was made only in one cultivar of tulip.
Findings/Conclusions: The application of 5 µM of Ce had a positive effect in the tulip cycle, by stimulating bulb sprouting, the formation of the floral bud, the coloration, and the advance of the flowering cycle
Editorial
Authors: Rocha-de-Oliveira Sidinei
Published: May 2021

Editorial
Sala multimídia: novas tecnologias para potencializar o ensino e a aprendizagem
Authors: Santos Lúcia Maria Gonçalves da Cruz
Published: May 2021

A educação é uma das dimensões essenciais na evolução do ser humano, pois em cada conquista rumo à civilização, faz-se presente junto a esta, a necessidade de transmissão aos semelhantes. Ela é a base do conhecimento para todas as pessoas Os grandes desafios que os países enfrentam hoje se encontram a melhoria da qualidade do ensino, a permanência dos estudantes na escola e a ampliação do acesso à educação. Tais desafios estão associados ao papel cada vez mais importante que a educação vem assumindo em todo o mundo por sua relevância na busca do desenvolvimento sustentável da sociedade, na construção da cidadania e no combate à exclusão social. A construção de políticas públicas baseadas nessa perspectiva constitui-se estratégia primordial para assegurar a universalização do acesso, a permanência e a aprendizagem em todas as etapas da educação básica. A mudança de ideologia impregnada na sociedade, uma alteração da concepção de ensino e do papel da escola enquanto instituição social. Busca-se uma escola democrática, pluralista, que venha valorizar a diversidade frente às problemáticas sociais perpassadas pelo educador e educando. No Colégio Estadual Dulce Petri buscamos constantemente melhorar a qualidade do ensino, através de aulas atrativas e projetos multidisciplinares. Um dos fatores que influenciam a aprendizagem é o ambiente, o espaço onde é realizada a aprendizagem. Pensando nisso, apesar do pouco espaço físico que a Unidade Escolar tem, optamos em transformar um dos espaços e criar a sala multimídia. Para realização deste projeto o valor solicitado ao edital será de R$ 27.439,00, que será destinado a reforma da sala, material de consumo, compra de mobiliário e de equipamento multimídia e serviços. O projeto vem de encontro aos anseios de professores e alunos por um espaço diferente e atraente que ajude a motivar a aprendizagem, pois as aulas serão ministradas com equipamentos diferentes aos utilizados nas salas de aula convencionais da Unidade Escolar. Este projeto vem de encontro ao EDITAL nº 2 – Projetos Inovadores em Educação – Fundação Novo Brasil – Educação para o Futuro, da qual esperamos o apoio financeiro para implementação deste empreendimento que segue nos próximos capítulos.
Programação de computadores para melhoria da aprendizagem
Authors: Moralles Adriana
Published: May 2021

Estamos vivendo uma realidade onde a tecnologia invadiu todos os ambientes de trabalho, escolas, casas... O que temos hoje em termos de tecnologia , será obsoleto daqui 2, 3 anos, tamanha é a rapidez da evolução tecnológica. As opções de trabalho vão sofrer uma grande transformação. Segundo pesquisas, ainda não conhecemos a maioria das ocupações profissionais que existirão daqui a 10 anos. Seguindo essa lógica e baseados nos resultados da escola em avaliações externas e internas, percebemos uma fragilidade dos alunos em relação ao desenvolvimento do raciocínio lógico e na interpretação de textos/dados. Os resultados das avaliações como SARESP e ENEM, trouxeram a consciência da necessidade de aprofundar conhecimentos nas áreas da matemática(resolução de problemas) e português (interpretação de textos/dados). Pensamos em aliar a tecnologia, através da programação em computadores, para a melhoria da aprendizagem dos alunos, visando o desenvolvimento do raciocínio lógico e favorecendo também a interpretação de textos/dados. O Plano de empreendimento escolhido “Programação de computadores para melhoria da aprendizagem”, foi pensado a partir da necessidade de melhorar o raciocínio lógico e a criatividade dos alunos, através de situações-problema reais que necessitam de soluções. Contamos com uma equipe de professores dinâmicos, com disposição para aprender e abertos à mudanças que favorecem a aprendizagem dos alunos. Para a realização do Plano de Empreendimento, o valor solicitado ao edital será de R$ 23.891,95 destinados a compra de computadores, softwares, contratação de professor especializado em programação de computadores, treinamento de professores, despesas com material de consumo e serviços, despesas correntes e manutenção. Esperamos contar com o apoio financeiro necessário para o desenvolvimento desse Plano de Empreendimento que tem como objetivo criar uma geração de pessoas confiantes e que possam controlar e manipular o mundo digital, em vez de apenas consumir passivamente o conteúdo. Nos capítulos seguintes poderemos conhecer melhor o Plano de Empreendimento que já vislumbra os frutos desse trabalho promissor. Acreditamos que a educação é fundamental para melhorar e desenvolver as pessoas em busca de um mundo melhor.
DICIONÁRIO ON LINE SPREAD THE SIGN digital para a educação: Integração internacional de um recurso para surdos
Authors: Azevedo Renata Rodrigues
Published: May 2021

O Projeto que estamos desenvolvendo, teve inicio com a Profª Ruth Mariani, Doutoranda pela UFF, que atendeaproximadamente 40 alunos surdos na sala de recurso. Percebemos sempre que após os Conselhos deClasses, a maioria dos alunos surdos apresentava baixo rendimento, com dificuldades em compreenderconceitos das disciplinas. Sabemos que alguns erros na interpretação de uma aula podem prejudicar oprocesso de aprendizagem do aluno surdo.A comunicação é imprescindível para todos, inclusive para os alunos surdos, para que estes tenham, atravésde uma melhor relação, condições de não exercerem seu trabalho isolada e mecanicamente, como semprelhes foi exigido e feito, mas que saibam e sintam sua real inserção no ambiente escolar, o que é fundamentalpara seu desenvolvimento profissional e pessoal. Assim a implantação do Dicionário on line Spread the sign,pioneiro no Brasil, poderá ampliar a comunicação e o acesso destas pessoas com deficiências.Tentamos nos adequar as dificuldades que são apresentadas, pois promover a inclusão significa uma mudançade postura, implica em quebra de paradigmas, em reformulação do nosso sistema de ensino para a conquistade uma educação de qualidade e prevendo a permanência de todos os alunos na escola independentementede suas diferenças e necessidades.