bluuebunny/crossref_metadata_2025 huggingface dataset:
SYNTHETIC STUDY OF Pc-2, AN ACTIVE COMPOUND FROM INDONESIAN RED BETEL LEAF
Authors: Ritmaleni  , Kim Dong-Hwi
Published: March 2023

PC-2 is one of the active compounds isolated from Indonesian red betel leaf. The structure of the compound is named 2-allyl-4-(1'-hydroxy-1'-(3",4",5"-trimethoxyphenyl)propan-2'-yl)-3,5-dimethoxycyclohexa-3,5-dienone and included in the neolignan’s structure category. This compound was reported to have very good biological activity in giving antiproliferative effects on human breast (T47D) cells. From 2.12 g of its leaf methanolic extract, only 12.1 mg of Pc-2 was collected. This amount is too small to do more studies about its biological activities. The synthetic work should be applied to get a sufficient amount. This paper is aimed to explain the synthetic study and design of the Pc2 compound. The first approach is by involving the aldol reaction in the synthetic pathway through the disconnection approach. The result showed that this attempt did not work very well. The second approach is to design the new synthetic pathway by using the synthia Organic Retrosynthesis Software by Merck. This software gave a reasonable result to be tried. The result proposed the use of the Suzuki coupling reaction for the new synthetic pathway of Pc-2.
SYNTHESIS OF DIHYDROTETRAZOLOPYRIMIDINE DERIVATIVES AS ANTICANCER AGENTS AND INHIBITOR OF α-GLUCOSIDASE
Authors: H. Suwito  , N. Kurnyawaty  , Haq K.U. , R. Ramadhan  , A. Abdulloh  , Hardiyanti H.D. , P. Phuwapraisirisan
Published: March 2023

A series of dihydrotetrazolopyrimidine derivatives were prepared to utilize a three-component Biginelli reaction from ethyl 3-oxo butanoate, 5-amino tetrazole, and various aromatic aldehydes as reactants, pTSA as a Brønsted acid catalyst, and ethanol as the solvent. The structure of the prepared compounds was established by spectroscopic evidence, FTIR, HRMS, and NMR (1H- and 13C-) spectra. The electronic properties of the aromatic aldehyde's substituents affected the reaction's time and yield. Substituents possessing electron-donating character accelerated the reaction time but decreased the reaction yield, whereas substituents with electron-withdrawing properties slowed the reaction but increased the yield. The prepared compounds exhibited moderate to strong anti-proliferative activities against 4T1 and HeLa cancer cell lines. Compound Ethyl (E)-5-methyl-7-(1-phenylprop-1-en-2-yl)-4,7- dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylate and compound Ethyl 7-(1H-indol-3-yl)-5-methyl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylate) showed strong anti-proliferative activities in vitro through induction apoptotic cells death mechanism. In addition, five of the synthesized compounds exhibited better inhibitory activity of α-glucosidase than quercetin, the positive control.
PHARMACOLOGICAL POTENTIAL OF POLYHERBAL FORMULATION KABASURA KUDINEER: A REVIEW
Authors: Suman Shwetang , Rameshwari Rashmi
Published: March 2023

Diabetes is a long-term medical condition in which the body has difficulty converting food into energy. High blood glucose levels are produced by poor glucose management, which alters the overall metabolic process of the body. The accumulation of abnormal (excess) blood glucose and the inability to metabolize plasma glucose causes lethal damage to the body's major organs or organ systems such as heart disease, nephropathy, retinal degeneration, sensory loss, and even premature death. Despite the administration of long-term medications, available diabetes mellitus therapy is unable to cure and unable to prevent patients from key organ damage. Diabetics have a significant financial burden, in addition to drug-drug interactions. A tremendous amount of data and proof has been amassed, proving medicinal plants' enormous potential. Plants are a naturally occurring source of therapeutic strategy for mankind. In accordance with the literature review, people who have metabolic syndrome are more likely to contract COVID-19. To overcome pandemics, we need efficient and effective herbal management. Kabasurakudineer is a polyherbal formulation that is gaining acceptance in the medical world. It may have a synergistic impact that is advantageous in the therapy of metabolic illnesses such as diabetes. Type 2 diabetes is expected to affect 640 million people by 2040, with 70% of those affected being hypertensive and predisposed to obesity and dyslipidemia.
ANTICANCER EVALUATION AND SYNTHESIS OF STYRYLDIHYDROPYRIMIDINE VIA BRONSTED ACIDCATALYZED VINYLOGOUS ALDOL REACTION
Authors: Haq K. U. , R. Ramadhan  , Kristanti A. N. , H. Suwito
Published: March 2023

Vinylogous aldol condensation on some dihydropirimidine (DHPM) derivatives has been successfully performed using p-toluenesulfonic acid as a Brønsted acid catalyst. The pure products could be obtained without further purification. Employing this method, 20 styryldihydropyrimidine derivatives have been successfully synthesized wherein 19 of them are new compounds. The structures of the reaction products were elucidated by spectroscopic methods (IR, NMR, MS), while their cytotoxic activities were determined toward two cancer cell lines HeLa and MCF-7. Some compounds showed high activity better than doxorubicin as a positive control.
MICROWAVE IRRADIATION SYNTHESIS OF NITROGENDOPED Ag/MWCNT/ZnO NANOCOMPOSITE FOR PHOTOCATALYTIC APPLICATION
Authors: M. Singh  , P. Kumar  , Singh N. S. , A. Jain
Published: March 2023

In this proposed research work, Zinc oxide is fabricated with carbon nanotubes, nitrogen, and silver. The conclusion of the distinctive hybrid of dopants on the ZnO/MWCNT nanocomposite was studied. Acidic and basic nature dyes are used to check the efficiency of the composite photocatalyst. The hydrothermal & microwave route was adapted for combining mesoporous nanocomposite samples. The XRD analysis confirmed the information to the nanoscale crystal with the hexagonal dimension of ZnO. The observation of UV-vis spectra validates its photocatalytic competency in the visible beam as an outcome of the reduction in the bandgap energy. The proficiency of the photocatalyst was additionally entrenched over the axing in electron-hole recombination activity referring to dwindling PL intensity. The BET inspection supports the mesoporous structures of the samples. The SEM micrograph revealed the existence of agglomeration in nanoparticles with MWCNT while the perusal of TEM images established the existence of a 16–24 nm diameter of the MWCNT. Furthermore, the EDX analysis confirmed the presence of the Zn, N, O, Ag, and C.
MICROWAVE FACILITATED THE SYNTHESIS OF ISOPROPYL MYRISTATE AND PALMITATE USING HETEROGENEOUS CATALYST
Authors: Tarigan J.B. , Barus D.A. , G. Brahmana  , Hulu D.A. , Sembiring W.S. , S. Perangin-angin  , Sitepu E.K.
Published: March 2023

In the present research, a microwave-intensified esterification reaction of myristic acid and palmitic acid with isopropyl alcohol (IPA) to produce an emollient ester using Amberlyst46 as a catalyst was studied. The effect of the ratio of molar fatty acid to alcohol, catalyst weight, reaction time, and microwave power on isopropyl myristate (IPM) and isopropyl palmitate (IPP) conversion and yield were investigated systematically. The results showed that catalyst weight and microwave power significantly affect the conversion and yield of IPM and IPP, respectively. The maximum conversion and yield of IPM were achieved under microwave irradiation power of 100% and catalyst weight of 15 wt.% while only 50% microwave power was required to achieve maximum conversion and yield of IPP using 18 wt.% of catalyst weight. These findings show that microwave-facilitated esterification reaction is a promising alternative method to produce emollient ester as the maximum conversion could achieve in a short reaction time.
NATURAL ACID-CATALYZED SYNTHESIS OF 6,6'-(((3,3'- DIMETHOXY-[1,1'-BIPHENYL]-4,4'- DIYL)BIS(AZANYLYLIDENE))BIS(METHANYLYLIDENE))BIS( 2,4-DICHLOROPHENOL), ITS CONVENTIONALLY SYNTHESIZED METAL COMPLEXES AND THEIR POTENTIAL AS BIOLOGICAL AGENTS
Authors: M. Thakor Priteshkumar
Published: March 2023

Organic research has recently focused on the development of a more environmentally friendly process that uses alternate reaction media in place of harmful and expensive catalysts. So here a facile protocol was developed for the green synthesis of a novel Schiff base ligand, and the synthesized ligand was characterized using physicochemical techniques. The homobinuclear complexes of synthesized ligands made of Iron (II), Cobalt (II), Manganese (II), Nickel (II), Zinc (II), and Copper (II) were characterized through the FTIR technique after synthesizing them conventionally. The in-vitro antimicrobial and antioxidant activities were examined for all the synthesized compounds
(.Effect of Quizalofop-p-Tefuryl herbicide in combination with Johnson grass extract on weed control in flax crop (Linum usitatissimum L
Authors: NEMR RASOL HASSAN , HAMMOOD WTHEQ FALHI
Published: March 2023

A field experiment was carried out to determine the best effect of Johnson grass extract, alone or in combination with Quizalofop-p-Tefuryl herbicide, to achieve the benefit of their integration into weed control programs to reduce reliance on herbicides in controlling weeds, increasing yield and reducing environmental pollution by these herbicides. The randomized complete block design (RCBD) with the split plot arrangement by three replicates was applied, the distance between the rows (20, 25 and 30 cm) represents the main plots. The control treatments : weed-free (T1), application Quizalofop-p-Tefuryl at rate 2 ml/l (T2), Johnson grass extract at rate 18 l/ha (T3), half herbicide amount + half extract amount (T4) and weedy treatment (T5) , represent the sub-plots . The results showed that of distance 20 cm achieved lowest density of companion weeds (52.20 weeds/m2) and highest percentage of weed control (50.42) after 60 days of application, and highest seed yield, oil yield reached 1.781 and 0.675 t/ha, respectively. The distance 30 cm achieved highest number of capsules (14.790 capsules/plant) seeds (8.337 seeds/capsule) and highest weight of 1000 seeds reaching 7.379 g. Application of Quizalofop-p-Tefuryl (T2) achieved lowest weed density (54.78 weeds/m2), highest weed control percentage (52.22) after 60 days of application. Besides, highest number of capsules (14.956 capsules/plant), seeds were (8.580 seeds/capsule), highest weight of 1000 seeds was 7.611 g, and highest seed yield , oil yield reached 1.779 and 0.7113 t/ha, respectively. Distance 20 cm with treatment (T2) achieved lowest number of weeds reaching (44.67 weeds/m2), highest percentage of weed control (57.59) after 60 days of application, highest seed yield, oil yield reached 2.067 and 0.7267 t/ha, respectively. Distance 30 cm and treatment (T2) achieved highest number of capsules (16.05 capsules/plant), seeds (8.580 seeds/capsule) and highest weight of 1000 seeds reaching 7.873 g.
Аналіз провідного вітчизняного та зарубіжного досвіду з підвищення дослідницької спроможності університетів України в умовах війни та повоєнного відновлення у контексті імплементації концепції "Відкрита наука"
Authors: Луговий Володимир , Драч Ірина , Петроє Ольга , Зінченко Віктор , Мєлков Юрій , Жиляєв Ігор , Регейло Ірина , Камишин Володимир , Базелюк Наталія
Published: March 2023

У препринті представлено результати другого етапу наукового дослідження за темою "Підвищення дослідницької спроможності університетів України в умовах війни та повоєнного відновлення у контексті імплементації концепції "Відкрита наука" (державний реєстраційний № 0122U200775). Розділи препринту відображають результати аналізу та узагальнення зарубіжного та вітчизняного досвіду щодо реалізації тенденцій і механізмів інтеграції освітньої і дослідницької діяльності університетів (розділ 1); реалізації політики і процедур імплементації концепції "Відкрита наука" в університетах (розділ 2); підвищення відповідальності дослідницької діяльності університетів (розділ 3); концепції "Відкрита наука" як механізму трансформації дослідницької діяльності університетів задля досягнення цілей стійкого розвитку (розділ 4); ціннісні виміри демократизації наукової діяльності (розділ 5); регулювання дослідницької діяльності університетів у мирний час, в умовах війни (військового стану) та повоєнного відновлення та розвитку (розділ 6); розвитку дослідницької інфраструктури університетів (розділ 7); моделювання е-інфраструктури університетів для розвитку відкритої науки в Україні (розділ 8). Адресовано представникам університетської спільноти, усієї когорти науково-педагогічних і наукових працівників закладів вищої освіти, академічних, наукових організацій та установ, фахівців фінансуючих структур, громадськості, а також публічним службовцям різних гілок і рівнів влади, що опікуються науковою і науково-технічною діяльністю та вищою освітою в Україні.
НАУКОВО-ДОСЛІДНИЦЬКА КОМПЕТЕНТНІСТЬ МАЙБУТНІХ ОФІЦЕРІВ-ПРИКОРДОННИКІВ ЯК ВАЖЛИВА СКЛАДОВА ПРОФЕСІЙНОЇ ПІДГОТОВКИ
Authors: ТОРІЧНИЙ Олександр
Published: March 2023

Наведено науково-теоретичну обумовленість науково-дослідницької компетентності майбутніх офіцерів-прикордонників, що розглянута в контексті аналізу сутності ключових понять: “науково-дослідницька компетенція” і “науково-дослідницька компетентність”. Науково-дослідницьку компетентність майбутніх офіцерів-прикордонників визначено як інтегративну якість особистості, щопоєднує в собі знання, уміння, здатність до опанування сучасних технологій проєктування й організації наукового дослідження на основі компетентнісного підходу до вирішення проблем професійної діяльності; сформованість особистісно значущих якостей фахівця; здатність до визначення цілей, завдань, стратегії професійної діяльності; готовність використовувати результати наукових досліджень для забезпечення ефективності власної професійної діяльності; здатність до вирішення професійних завдань шляхом розуміння фундаментальних засад військово-професійної діяльності. На підставі певного змісту науково-дослідницької діяльності курсантів (проєктувальної, інформаційної, аналітичної, практичної) виокремлено компоненти науково-дослідницької компетентності майбутніх офіцерів-прикордонників: мотиваційно-ціннісний, інтелектуальний, конструктивно-проєктивний, організаційно-комунікативний, інформаційний та рефлексивний. При цьому самостійна діяльність курсантів щодо освоєння дослідницьких умінь та навичок, активізована дослідницьким підходом у навчанні, сприяє формуванню науково-дослідницької компетентності майбутніх офіцерів-прикордонників. Визначальними у формуванні дослідницьких умінь курсантів є методика й організація їхньої навчально-пізнавальної та науково-дослідницької діяльності, реалізація якої здійснюється у кілька етапів: орієнтаційно-дослідницький; організаційно-дослідницький; науково-дослідницький.
Uma reflexão sobre a acriticidade social em tempos de COVID19
Authors: Calais Mariana Perle de , Pinheiro Jeane Macedo de Oliveira , Alves Cléber Consoni , Consoni Fátima Simone Silva Pereira
Published: March 2023

O mapa da covid-19 no mundo registra números elevados de casos e de mortes, no Brasil os discursos conflitantes entre Governo, Estados e Municípios dificultaram a adesão da população às medidas de controle do contágio, como resultado,diminuir a circulação de pessoas em locais públicos acabou causando desgaste e baixa aderência. Neste ínterim, cabe discutir a formação moral do sujeito. Jean Piaget e Lawrence Kohlberg organizaram estudos que levaram a uma teoria universal e estruturalista do desenvolvimento moral. Em face da saúde física e mental da coletividade, discutir sobre moralidade contribui para que comportamentos individualistas, fragilizados pela fragmentação e conduta moral heterônoma possam ser refletidos tendo em vista valores universais, a partir da cooperação e do respeito mútuo.
O despontar de uma nova cultura de comunidades budistas Shin pelo Brasil a partir de sua visibilidade na internet
Authors: Algieri Jean Jacques , Jesus Leomar Nascimento de
Published: March 2023

O presente trabalho pretende refletir sobre o formato de comunidade virtual da ordem Shin Ōtani, pertencente à escola budista Jōdo Shin, no Brasil, por conta de sua visibilidade nos últimos anos, através da internet, em uma possível expansão para além dos templos físicos. Com o advento da internet e das redes sociais, o ensinamento budista se tornou acessível a todos lugares e pessoas, passando a despertar interesse público, antes delimitado à etnia japonesa imigrante, a qual trouxe o Budismo para o Brasil. O trabalho será exposto em três seções: primeiramente o estabelecimento do Budismo japonês em terras brasileiras, sua transição enquanto instituição étnica para um formato nacional e a crescente demanda via internet. Na segunda parte pensaremos o mundo digital como meio de acesso à formação religiosa, refletindo sobre o papel das instituições, em especial budistas e a sobrevivência na nova configuração de grupos religiosos virtuais. E, por fim, refletiremos sobre a possibilidade de comunidades Shin a partir do mundo virtual, como espaço de experiência religiosa, comparado à época do Mestre Shinran por suas cartas aos fiéis nas reuniões caseiras e ainda o processo de aculturação da ordem Shin Ōtani derivada de um Budismo étnico japonês por convertidos brasileiros. Esta pesquisa conta com levantamento bibliográfico de autores como Hervieu-Léger (2015), Berger (1985), Usarski (2009) e Ries (2017) e com pesquisa quantitativa simples. O resultado deste trabalho poderá contribuir para a reflexão e operacionalização de novos formatos de presença e atuação da comunidade Shin Ōtani no Brasil na era digital.
O que é a política hoje?
Authors: Ruzza Antonio
Published: March 2023

A política hoje continua sendo uma atividade muito importante, apesar do grande número de pessoas que mostra um desprezo para ela e se orgulha desse sentimento. Porém, me parece que o aspecto emocional é mais difuso, se comparado às ações e aos temas de 5-6 décadas atrás, quando o aspecto racional e os grandes planos pareciam prevalecer. O professor Sidnei citou a presença desta característica na política atual, ao lado de um aspecto instrumental, aquele das redes sociais que permitem a difusão das mentiras mais absurdas, aceitas pelas massas mais despreparadas e que confiam cegamente em um líder populista. Isso não é surpreendente, já que vários filósofos, como Maquiavel e Rousseau, mostraram como é fácil para um príncipe ou para um déspota ou para um oportunista encontrar pessoas fáceis de enganar: é só possuir uma boa capacidade retórica, que por isso Hobbes e Nietzche condenavam por ser manipuladoras; porém, hoje, numa sociedade mais complexa, é necessário apresentar alguma ideia genérica, algum valor a ser perseguido. Mas voltando ao aspecto emocional, que mereceu o nome de psicologia de massas, além dos citados Le Bon e Freud, gostaria lembrar Reich, que justificou o sucesso do fascismo entre as duas guerras mundiais, a partir também de um erro dos marxistas: estes reduziram tudo à discussão econômica (salário, desemprego, meios de produção, exploração), e desconsideraram que há um fator, que Reich chama de misticismo (não em sentido religioso), que prevalece sobre a teoria puramente econômica das condições materiais. O seu pensamento continua atual e permite entender certas ações e comportamentos.
O S.I.M. – Sistema de Informação de Marketing para a elaboração de planos de marketing e estudo do comportamento do consumidor
Authors: Proetti Sidney
Published: March 2023

Este texto, fruto de um Estudo Qualitativo e de Pesquisa Bibliográfica, visa a apresentar o uso da Pesquisa de Marketing, pelo S.I.M. – Sistema de Informação de Marketing, como elementos de busca e estudo de cenários de mercado. Também demonstrará o S.I.M. como atividade de marketing como analisar, organizar, planejar, implementar e controlar, bem como as necessidades, análises e distribuições de informações de marketing obtidas em pesquisas de mercado, visando a elaboração de um Plano de Marketing. Finalmente, o texto visa a apresentar o Modelo de Comportamento do Consumidor, que é o ponto essencial do S.I.M. e do Plano de Marketing de uma organização.
Performa Reproduksi dan Body Condition Score Kerbau Rawa (Bubalus bubalis) Betina di Pulau Lanting
Authors: Salsabela Annisa , Suhardi
Published: March 2023

Tujuan dari penelitian ini adalah untuk mengevaluasi performan reproduksi untuk pengembangan populasi kerbau rawa pada Desa Pulau Lanting. Penelitian dilaksanakan pada 22 Oktober sampai dengan 5 November 2022 di Desa Pulau Lanting, Kabupaten Kutai Barat, Provinsi Kalimantan Timur. Sampel yang digunakan adalah 30 ekor kerbau yang dipilih menggunakan metode purposive sampling dengan kriteria yaitu berjenis kelamin betina, kerbau telah melahirkan minimal 2 kali dan dipelihara di wilayah Pulau Lanting minimal 2 tahun. Data performa reproduksi dan body condition score (BCS) disajikan dalam bentuk rataan dan standar deviasi kemudian dijabarkan secara deskriptif. Hasil dari penelitian ini menunjukkan bahwa kerbau memiliki umur kawin pertama 34,90±1,03 bulan, periode kebuntingan 10,50±0,39 bulan, umur beranak pertama 45,93±2,1 bulan, days open 2,86±0,47 bulan, calving interval 13,61±0,98 bulan, efisiensi reproduksi 70,22%, dan mortalitas 16,11% sedangkan untuk Body Condition Score  memiliki rata-rata 3,6±0,5. Nilai BCS adalah 3,6±0,5 dengan hasil uji korelasi adalah BCS berhubungan negatif terhadap umur kawin pertama, umur beranak pertama, dan calving interval.
Prevalensi Escherichia coli pada Feses Sapi Simmental di Pasar Ternak Kota Payakumbuh
Authors: Putri Ii Amelya , Zelpina Engki , Noor Prima Silvia , Lutfi Ulva Mohtar , Suliha
Published: March 2023

Escherichia coli (E. coli) adalah bakteri yang biasa hidup disaluran pencernaan dan bisa menyebabkan colibacillosis yang biasanya menyerang pada ternak muda dan  dapat ditularkan melalui saluran pencernaan,  pusar yang masih basah, intra uterina serta bersifat patogen apabila berada ditempat yang bukan habitatnya. Escherichia coli yang merupakan bakteri komensal atau flora normal di peritoneum atau usus bagian bawah. Bakteri E. coli dapat memproduksi racun yang dapat menimbulkan penyakit. Salah satu racun yang paling sering teridentifikasi adalah Shiga Toxinproducing Escherichia coli. Sebanyak 60 sampel feses yang terdari dari ( 30 indukan Simmental dan  30 pedet) yang diperoleh di pasar ternak Kota Payakumbuh. Data dianalisis secara deskriptif dengan keberadaan E. coli pada saluran pencernaan sapi di Pasar Ternak Kota Payakumbuh berdasarkan umur, jenis kelamin, dan kondisi ternak diare atau tidak. Hasil penelitian menunjukkan bahwa prevalensi E. coli pada feses sapi Simmental di Pasar Ternak Kota Payakumbuh adalah 91,6%. Prevalensi pada jenis sampel tertinggi pada sampel indukan sebesar 96,6% dan pedet 86,6%. Sapi berumur 48-60 bulan memiliki prevalensi tertinggi sebesar 100%. Pedet didapatkan hasil prevalensi pedet betina lebih tinggi dibandingkan dengan pedet jantan dengan prevalensi sebesar 92,3%. Prevalensi sampel diare yang terinfeksi  E. coli sebesar 100%.
Pengaruh Penambahan Ekstrak Jahe Merah (Zingiber officinale Var. Rubrum) Terhadap Kualitas Mikrobiologi Daging Ayam Petelur Afkir
Authors: Mutmainna Andi , Irmawaty  , Melani Aprilia , Thaha Aminah Hajah
Published: March 2023

Jahe merah (Zingiber offinale Var. Rubrum) salah satu tumbuhan herbal dan pengawet alami daging karena terdapatnya senyawa bioaktif. Senyawa ini dapat meningkatkan kualitas daging dengan menghambat pertumbuhan mikroba. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan ekstrak jahe merah pada kualitas mikrobiologi daging ayam afkir. Rancangan Acak Lengkap (RAL) digunakan dengan 4 perlakuan yaitu P0 (kontrol/tanpa perlakuan), P1 (penyimpanan 2 jam), P2 (penyimpanan 4 jam), dan P3 (waktu penyimpanan 6 jam). Penelitian ini menguji TPC, E. coli, dan Coliform. Anova dan BNT digunakan untuk analisis data. Ekstrak jahe merah (Zingiber officinale Var. Rubrum) berpengaruh nyata pada uji Coliform tapi tidak berpengaruh pada TPC, dan E. coli.
Pengetahuan dan Preferensi Konsumen Yogurt di Kota Jambi
Authors: Rosana Mayang , Winarto Adi , Pisestyani Herwin
Published: March 2023

Yogurt adalah produk olahan susu yang diproses dengan cara fermentasi dan termasuk pangan fungsional, karena memiliki manfaat kesehatan yang besar bagi masyarakat. Tujuan penelitian ini adalah mengidentifikasi faktor-faktor yang memengaruhi pengetahuan dan preferensi konsumen Yogurt di Kota Jambi. Data kuesioner dikumpulkan dari 100 responden yang disebarkan melalui google form secara online. Karakteristik konsumen yogurt di Kota Jambi, yaitu sebagian besar perempuan (70%), berumur kurang dari 20 tahun (53%), berpendidikan menengah ke atas (SMA) (64%) dan berstatus sebagai pelajar atau mahasiswa (84%) yang diberikan uang jajan oleh orang tua kecil dari Rp 1.000.000,- per bulan (52%). Setiap bulannya, konsumen mengonsumsi yogurt secara rutin (58,75%) yang dibeli dari supermarket/minimarket (96,25%). Konsumen lebih menyukai yogurt cair (81,25%) dan dikemas botol plastik (60%), dengan rasa buah (83,75%), serta dikonsumsi langsung (78,75%). Bagi konsumen, yogurt adalah camilan (77,5%) yang disimpan di kulkas (±4 ºC) (88,75%). Tingkat Pengetahuan konsumen terhadap yogurt kurang baik (40,6%), sehingga pertimbangan konsumen dalam membeli yogurt yaitu logo halal 37%, masa kadaluarsa 35% , kebersihan tempat berjualan 25% dan terdapatnya logo NKV dalam kemasan sebanyak 3%.
Profil Organ Dalam Broiler Dengan Penambahan Probiotik Effective Microorganism-4 (EM-4) Dalam Air Minum
Authors: Ananda Suci , Hifizah Amriana , Kiramang Khaerani , Jamili Muhammad Arsan , Mutmainna Andi , Rismawati
Published: March 2023

Probiotik adalah salah satu feed Additif yang di dalamya terkandung sebuah mikroorganisme yang memiliki fungsi dalam mengontrol komposisi bakteri dalam menekan jumlah bakteri merugikan dalam saluran pencernaan agar mampu menambah nilai daya cerna serta penyerapan nutrisi yang ada di saluran pencernaan pada unggas. Penelitian ini dilakukan agar dapat mengetahui profil organ dalam ayam broiler dengan pemberian probiotik Effective Microorganism-4 (EM-4) di dalam air minumnya. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan jumlah Perlakuan sebanyak 4 dan ulangan sebanyak 3 kali, tiap unit terdiri dari 3 ekor ayam sehingga total ayam yang dipergunakan yaitu 36 ekor. Adapun perlakuan yang diberikan adalah yaitu P0= Ransum tanpa probiotik (Perlakuan Kontrol), P1= Ransum + EM4 1 ml/ liter air minum/ hari, P2= Ransum + EM4 1,5 ml/ liter air minum/ hari, P3= Ransum + EM4 2 ml/ liter air minum/ hari. Durasi penelitian ini adalah selama 35 hari. Variabel yang diuji pada penelitian ini yaitu bobot relatif hati, proventrikulus, ventrikulus, bobot relatif segmen usus halus (duodenum, jejenum dan ileum) dan persentase panjang segmen usus halus (duodenum, jejenum dan ileum). Hasil penelitian menunjukkan dengan penambahan EM-4 dalam air minum tidak memberikan pengaruh nyata terhadap bobot relatif hati, proventikulus, ventrikulus, segmen usus halus (duodenum, jejenum, dan ileum) dan panjang relatif segmen usus halus (duodenum, jejenum dan ileum) namun, secara rerata terlihat peningkatan terhadap level yang berbeda. Adapun kesimpulan dari penelitian ini yaitu dengan penambahan EM-4 tidak berpengaruh nyata terhadap profil organ dalam ayam broiler berupa bobot relatif organ tambahan (hati, proventrikulus dan ventrikulus), bobot dan panjang relatif segmen usus halus (duodenum, jejenum dan ileum).
Fetish, Shaman and Root Seeking — Evgeny Antufiev’s Maze
Authors: Mu Di , Tang Yi
Published: March 2023

This essay is mainly about Evgeny Antufiev’s solo exhibition: “Twelve, wood, dolphin, knife, bowl, mask, crystal, marble and bones — fusion. Exploring material”. Analyzing his motivation and final presentation, aiming to grasp the unique national characteristics of Evgeny Antufiev’s artwork, exploring the source of Shamanic elements and how these effect his artwork. This article goes through “Fetish, Shaman, Rooting” three topics. Evgeny Antufiev’s artwork has special charisma, also provides a paradigm for contemporary art create activities. And the most important is to bring more dimensional thinking of artistic activity which intends to against the era.
A Study on Chinese-English Translation of the 2023 New Year Address of Chinese President Xi Jinping from the Perspective of Catford’s Translation Shifts Theory
Authors: Jia Tongxin
Published: March 2023

The New Year Address of 2023 delivered by Chinese president Xi Jinping can be an important and representative way for the international community to know about today’s China. As a text containing many long complex sentences with political connotations, the New Year’s address can be a challenge for translators. In this passage, a study on the Chinese-English translation of the New Year’s address under the guidance of Translation Shifts Theory of Catford was made, so as to see how this theory was applied in this kind of text, as well as to provide ways for translators to make shifts on some certain compositions in the sentences when doing Chinese-English translation, deliver proper and faithful translation, and show the Chinese spirits to the world.
French SLA State in Chinese University: A Study Case of CTBU
Authors: Harinivo Ramamonjisoa Mialitiana
Published: March 2023

Considered as one of the United Nations official language, English is widely spoke and learned as a Second Language among the world, after English comes French, German and Spanish. In China, after the introduction of English, other language like French, German, Russian and Japanese also took place in recent years, and French have been one of the most popular second language teached and learned as a subject but also field after English. With that state take into consideration, this article will briefly discuss about French acquisition as a Second language through Chinese undergraduate student in Chongqing Technology and Business University or CTBU.
Explore the Effective Ways to Cultivate the "Inner" Hearing of Lower Grade Children in Chinese Primary Schools
Authors: Tu Yiqi , Mazlan Chamil Arkhasa Nikko bin
Published: March 2023

The cultivation of inner hearing is one of the important components of music skills learning and mastery. Nowadays, music teachers begin to pay attention to students' inner hearing, but the current lack of effective training methods are available for teaching in China. Although there are many teaching methods to study inner hearing theories at home and abroad, none is based on low-grade music classes in primary school. In terms of physical development rules, the earlier the music needs to be learned, the better. Therefore, the purpose of this study is to provide a set of feasible teaching methods suitable for junior primary school students (6-8 years old) to cultivate music inner hearing, and to provide a feasible training method for improving the inner hearing of the lower grade of primary schools in China.
The Effect of Participatory Teaching Method Combined with Virtual Simulation System in Ultrasonic Imaging Teaching
Authors: Ao Meng , Zhang Yun
Published: March 2023

Objective: To explore the effect of participatory teaching method combined with virtual simulation system in the teaching of ultrasound imaging. Method: From September 2022 to December 2022, a total of 90 students from 2 classes of Grade 2019 in the Department of Imaging were selected. 45 people in the control group will adopt the traditional teaching method, and 45 people in the experimental group will adopt the participatory teaching method + virtual simulation system, to compare the teaching effect of the two groups. Results: The teaching satisfaction of the experimental group in teaching form (95.56%), teaching content (95.56%), student learning initiative (97.78%), learning interest (95.56%), practical operation (97.78%), etc. Higher than the control group, P<0.05; the theoretical knowledge and practical operation test scores of the experimental group were significantly higher than the control group, P<0.05. Conclusion: In the teaching of ultrasound imaging, choosing participatory teaching method combined with virtual simulation system can effectively improve students' theoretical knowledge and practical operation level, and strictly grasp the characteristics of ultrasound images, which is worth adopting.
Federation of Law Societies: Towards a Deeper Understanding of the Principles of Fundamental Justice
Authors: Mogyoros Alexandra
Published: March 2023

In Attorney General of Canada v. Federation of Law Societies of Canada, Cromwell J., writing for the majority, recognized a new principle of fundamental justice under section 7: a lawyer’s duty of commitment to the client’s cause. Discussion surrounding Federation of Law Societies has generally focused on the importance of solicitor-client privilege and of its significance for the independence of the bar. Relatively less consideration, however, has been given to how this case contributes to section 7 Charter jurisprudence more broadly. This paper seeks to fill this gap by exploring how Justice Cromwell’s reasons in Federation of Law Societies develop our understanding of the principles of fundamental justice. Specifically, this paper considers four insights that may be drawn from Cromwell J.’s analysis of the lawyer’s commitment to the client’s cause as a principle of fundamental justice explores, namely: (i) a principle of fundamental justice may be sub-divided into different aspects or variations of the same principle; (ii) solicitor-client privilege is not the only aspect of a lawyer-client relationship that has a constitutional dimension; (iii) this principle is distinctive as compared to previously-recognized ones, in that it is justified by engaging with a non-state actor’s role in the architecture of the legal system; and (iv) this one evades being classified as either a substantive or procedural principle. 
Blurred Boundaries: Social Media Privacy and the Twenty-First-Century Employee
Authors: Abril Patricia Sánchez , Levin Avner , Riego Alissa Del
Published: March 2023

This paper discusses the future of employee privacy in social media.

Part I reviews the extant legal landscape with an emphasis on three general areas of employer activity related to employees’ online activities: (1) monitoring and surveillance of employee social media profiles, (2) evaluation of applicants’ social media profiles and online speech in making hiring decisions, and (3) limiting employees’ off-duty online activities.

Part II reports the results of an empirical research project into the expectations of young employees regarding the role of social media in the workplace. We asked respondents about a wide range of topics related to social media, such as the extent of personal information they post online, the privacy-protective measures they employ on social media sites, their level of concern regarding their privacy online, and their attitudes and expectations regarding the use of social media in the workplace. Despite granting employers access to information about their private lives by participating online, respondents expect that work life and private life should be generally segregated — and that actions in one domain should not affect the other.

Guided by the survey findings and legal examples from international jurisdictions, in Part III we offer workable recommendations designed to protect employees’ desire to maintain some separation between personal and professional contexts.
From cybercrime to cyberwar? The international policy shift and its implications for Canada
Authors: Levin Avner , Goodrick Paul
Published: March 2023

Countries are creating strategies to defend themselves from cyberwar and cyberespionage in response to cyber attacks such as Stuxnet, Flame and the use of social media in national conflicts. Nations are grouping in blocs for these strategies along traditional international-relations lines. Combating cybercrime is becoming more difficult, and less important, as a result, since potential partners in crime-fighting must increasingly treat each other as cyber opponents. Canada should not abandon potential partnerships with China, Russia and their allies because of increased cyberwarfare concerns. Canada should strive for a middle ground that that will allow Canada to cooperate with every country as long as that cooperation advances the Canadian interest in a more secure cyberspace for Canadians.

 
Big and Little Brother: The Potential Erosion of Workplace Privacy in Canada
Authors: Levin Avner
Published: March 2023

Recent research shows that monitoring and surveillance of workers in Canada is increasing. The Canadian Federal Government, at the same time, is calling for increased access to proprietary databases for lawful purposes. Employers therefore face a distinct possibility that their monitoring and surveillance data will be routinely accessed by various government and law enforcement agencies. Since in many provinces workers enjoy little legal protection of their right to a private life, and since new legal protective measures are unlikely, employers must look to their role as socially responsible members of a liberal and democratic society, and respect the rule of law by minimizing their collection of personal worker information.
The Participant Perspective
Authors: Levin Avner
Published: March 2023

A discussion of the methodology of legal theory and its implications for jurisprudence. Methodological differences between Hart, Dworkin and Raz are highlighted through an examination of Hart's idea of the perspective of the participant in the legal system and the light it throws on the law. The analysis reveals how Dworkin and Raz share a prescriptive approach that can be contrasted with Hart's descriptive approach. I discuss how the methodology of these theorists informs their substantive positions as well as the debate between exclusive and inclusive positivism. Ultimately, I suggest how these mutually exclusive approaches complement each other.
Losing the Battle But Winning the War: Why Online Information Should Be a Prohibited Ground
Authors: Levin Avner
Published: March 2023

This paper contends that in the “war” to protect the privacy of individuals’ personal information online, the battle to limit the collection of such information has been lost. Existing personal information protection regimes, with their emphasis on notice and consent, have proven inadequate, especially in light of the advent of “big data analytics” and revelations of large-scale privacy violations by governments and corporations. I argue, however, that the war can still be won on another front — that of limiting the use of personal information. In developing this theme, I explore the notion of “network privacy,” which posits that information shared online within a given social circle is intended to stay within that social circle, and is not to be shared beyond its boundaries without permission. Currently there is no legal protection in Canada against the invasion of network privacy (though in several recent decisions, the courts have shown a more nuanced understanding of privacy in online information). One potential source of such protection might be the adoption of the “Oxford principles” formulated in 2013, which propose a new model for regulating the processing of information, one that is focused on the use of personal information rather than on its collection. In my view, though, those principles, as well as other proposals, would not provide sufficient protection. Instead, I outline an approach that is broadly similar to the prohibition against the use of information relating to protected grounds under Canadian human rights legislation. Under this approach, no action could be taken against an individual — including in the employment context — based on his or her online information, except where that information reveals criminal, illegal or unethical conduct, or causes significant harm to others.
Austin’s Complementary Jurisprudence
Authors: Levin Avner
Published: March 2023

The jurisprudence of Austin has long served as a straw man for positivism and as a punching bag for positivism's opponents as well as its more sophisticated promoters, such as Hart. This article discusses the richness of Austin's jurisprudence and its complementary nature - its ability as a theory to include a moral perspective on law that serves as a basis for hard legal power and authority.
Contentious terrain: defining a human rights museology
Authors: Carter Jennifer , Orange Jennifer
Published: March 2023

The work of museums is changing, radically. As the global rise of museums and museum networks dedicated to the subject of human rights over the past few decades has confirmed, museums can be beneficial to the dialog and ongoing negotiation of human rights between civil society and government institutions. Indeed, the foundational roles of museums as places of collecting, conserving and exhibiting artifacts of material culture have shifted significantly over the last quarter century in response to calls for greater social accountability to pressing contemporary issues – human rights, the environment, immigration and social justice among them. Human rights museums have specific responsibilities, however, and the positions these institutions take on human rights have both the opportunity and the danger of affecting human rights of future generations – a task these museums must consider with the greatest ethical sensibilities and concerns.

 
The Inter-American Court’s Environment and Human Rights Advisory Opinion: Implications for International Climate Law
Authors: Campbell-Duruflé Christopher
Published: March 2023

The Advisory Opinion of the Inter-American (IA) Court of Human Rights on Environment and Human Rights, released in February 2018, has the potential to usher in a new era for the relationship between climate law and international human rights law. This article begins with the Inuit Petition submitted to the IA Commission on Human Rights in 2005 to identify three legal challenges which it brought to light on the application of the international human rights framework to climate change: enforceability, causality, and extraterritoriality. By relying on examples from the Human Rights Council and the Paris Agreement negotiations, we show that these three issues continue to have an impact on the relationship between climate law and human rights. We then draw attention to the groundbreaking character of the IA Court’s Advisory Opinion, and in particular to the finding that the American Convention on Human Rights gives rise to an autonomous right to a healthy environment and to state duties that are both preventive and extraterritorial in nature. We suggest that the IA Court’s revisiting of the three legal hurdles provides an opportunity to close the gap between the disciplines of international human rights and climate law. 
Accountability or Accounting? Elaboration of the Paris Agreement’s Implementation and Compliance Committee at COP 23
Authors: Campbell-Duruflé Christopher
Published: March 2023

This article provides an analysis of progress regarding the modalities and procedures for the Paris Agreement’s Implementation and Compliance Committee up to cop 23. I use the perspective of legal accountability to address three points of long-lasting divergence between parties: whether the Committee will be tasked to require parties to justify their performance by making specific reference to applicable legal standards; the contentious question of mandating the Committee to assess the progress of parties on the achievement of their ndc targets; and the involved party’s degree of control over the measures adopted. I conclude that a richer approach to accountability calls for granting a substantive role to practices of legal justification, assessment, and consequences within the modalities for the Committee in all three cases. Subject to political acceptance, such a mandate has the potential to foster parties’ sense of trust, reciprocity, and legal obligation toward one another. 
Clouds or Sunshine in Katowice? Transparency in the Paris Agreement Rulebook
Authors: Campbell-Duruflé Christopher
Published: March 2023

This article identifies outstanding issues regarding the adoption of MPGs for the transparency framework of the Paris Agreement at the Conference of the Parties in Katowice in December 2018. The article first offers a definition of the concept of transparency, and reviews certain salient elements in the literature. This includes a warning that adopting transparency rules that elude questions of accountability of Parties for their domestic policies and equity in burden sharing may fail the objective of building the trust and confidence for which the transparency framework was adopted. The article next offers a brief overview of the requirements of Article 13 of the Paris Agreement, before assessing three key matters raised by the August 2018 draft of the MPGs in light of the literature and recent submissions by Parties. The article underscores the relevance of including a focus on ex ante accountability for climate policies in the way the transparency framework is set to operate, in view of the overall focus of the Paris Agreement on prevention of environmental harm. Comparing the potential of transparency rules to promote accountability of reporting and accountability of implementation of Parties’ commitments, it further argues for the inclusion of both foci in the modalities. Lastly, the article highlights that the Paris Rulebook presents a unique opportunity to craft specific roles for non-Party stakeholders in the operation of the transparency framework, thereby developing the links between the United Nations Framework Convention on Climate Change and transnational climate governance initiatives.
Методи вивчення високотехнологічних дисциплін
Authors: Карпюк Л.В. , Давіденко Н.О. , Ганжа С.А. , Гезеві Абдалхалех Гома Ахмед
Published: March 2023

У статті розглядаються питання та проблеми навчання студентів, з якими вони зустрічаються під час вивчення високотехнологічних дисциплін. У вищих навчальних закладах (ВНЗ) в сучасних умовах потрібен новий підхід до підготовки студентів різних рівнів навчання − якісний, технологічний. До підготовки фахівців галузі знань «Автоматизація та приладобудування» висуваються підвищені вимоги. Зважаючи на умови традиційної освіти, реалізація цих вимог пов'язана з певними труднощами. Впровадження високотехнологічних дисциплін в навчання дозволяє досить швидко розробляти та пропонувати студентам різноманіття варіантів індивідуальних завдань за великою кількістю тем з урахуванням рівня початкової комп'ютерної підготовленості студентів. При правильному підході САПР може бути прекрасною основою запровадження у освітній процес проєктного способу навчання. Суть його полягає втому, що викладач задає вихідні дані та формулює заплановані результати навчальної задачі. Студенти самі намічають проміжні завдання, шукають шляхи їх вирішення, а виконуючи проєкт, порівнюють отримані результати із затребуваними, при необхідності коригують регульовані параметри. У результаті вони набувають навичок самостійно «добувати» нові знання, вчаться застосовувати їх до вирішення практичних завдань, набувають першого досвіду дослідницької роботи. Але на шляху вирішення цієї проблеми вищі навчальні заклади сьогодні зустрічають низку серйозних труднощів, пов'язаних з недостатньою матеріальною базою (нестача потужних комп'ютерів, висока вартість ліцензійного програмного продукту тощо). Щоправда, низка великих компаній – розробників САПР – пропонують (безкоштовно) «урізані» студентські версії САПР, які можуть надати значну допомогу в навчанні. В свою чергу вивчення сучасних САПР та набуття навичок у роботі з ними, безумовно, сприятиме підвищенню якості підготовки інженерних кадрів, значно скоротить період часу, необхідний для адаптації молодого спеціаліста на робочому місці після закінчення вищого навчального закладу, суттєво підвищить його затребуваність з боку роботодавця. Крім того, використання у навчальному процесі систем автоматизованого проєктування, поряд з рішенням основного завдання, дає низку додаткових освітніх ефектів. Сумарна дія таких ефектів багаторазово покращує результати навчання. В даній статті розглядаються деякі відмінні риси САПР, які позитивно впливають на результативність підготовки сучасного спеціаліста.