bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of QRSL1 in Clinical Subtypes and Prognosis of Childhood B-cell Acute Lymphoblastic Leukemia
Authors: Yin Sha , Gao Wenjin , Fan Ye , Xia Rui , Duan Mingyue , Zhang Xi , Liu Ansheng , Zhang Yanmin
Published: June 2022

B-cell acute lymphoblastic leukemia (B-ALL) is the most common leukemia
in the pediatric population, caused by a malignant clonal proliferation
of B lymphoid progenitor cells. Identifying new molecular markers
related to B-cell development is helpful for investing the pathogenesis
of B-ALL, and is potentially important for clinical prognosis. We found
that B cells showed the highest expression of glutaminyl-tRNA
amidotransferase subunit QRSL1 (QRSL1) compared with other cells during
the differentiation and development of hematopoietic stem cells and the
expression of QRSL1 also gradually increases with the development of
human fetal B-cell. Moreover, QRSL1 expression was higher in the tissues
and cell lines extracted from patients with B-ALL than in corresponding
control tissues. In the TARGET cohort, EFS and OS decreased in B-ALL
with high expression of QRSL1, suggesting that QRSL1 was an independent
prognostic factor. And high QRSL1 expression is associated with more
bone marrow sites of relapse and TCF3-PBX1 gene fusions. Then analyzing
the gene expression of the TCF3-PBX1 gene fusion subgroup, the
significantly different gene expression between the QRSL1
 group and QRSL1  group
exhibited enrichment in cell development, suggesting that QRSL1 may
participate in leukemic cell development in childhood B-ALL. Therefore,
QRSL1 may be a molecule related to B cell development and is associated
with molecular subtypes of B-ALL. The high expression of QRSL1 is
associated with poor prognosis in patients with B-ALL, showing its
potential as a prognostic marker of B-ALL leukemia.
Dynamic stall prediction of an airfoil using upwind-based numerical solution of non-viscous equations
Authors: Razavi Seyed Esmaeil , adibi tohid , Hassanpour Hussein , soltani saeid
Published: June 2022

Determination of the critical attack angle at which dynamic stall occurs
has been a focus of research over the last few decades. This angle is
usually determined by solving the Navier-Stokes equations, which
includes viscosity, pressure, gravity, and acceleration terms. However,
this article predicts the critical attack angle using Euler equations
that do not contain viscous terms. The key contribution is the use of
the Euler equations to capture the vortices and predict stall dynamics.
The Euler equations are integrated and the resulting equations are
discretized by the finite volume method. A first-order upwind-based
method is used to calculate the convective fluxes at the cell boundaries
in the finite volume approach. A NACA 0012 airfoil is chosen for this
study at various attack angles with a Mach number of 0.3. Based on the
justification of Crocco’s theorem, the Euler equations successfully act
as Navier-Stokes equations. The vortex patterns are found to behave
independently of the artificial dissipation. All the vortices are
successfully predicted using the inviscid governing equations. The
obtained numerical results are validated by the existing experimental
and numerical data.
Historical loss of groundwater-dependent terrestrial ecosystems in undrained and artificial drained landscapes in Denmark
Authors: Sechu Gasper L. , Nilsson Bertel , Iversen Bo V. , Greve Mette B. , Greve Mogens H.
Published: June 2022

Groundwater-dependent terrestrial ecosystems (GWDTE) have been
increasingly under threat due to groundwater depletion globally. Within
the past 200 years, there has been severe artificial drainage of
low-lying areas in Denmark, leading to a gradual loss of GWDTE nature
habitat areas. This study explores the spatial-temporal loss of Danish
GWDTE using historically vectorized topographical maps. We carry out
geographic information systems (GIS) overlap analysis between different
historical topographic maps with signatures of GWDTE starting from the
19 century up to a current river valley bottom map
as a reference period. This is because farmworkers and monks have
practiced drainage by ditching since the early middle ages (1100-1200).
We then examine the changes in two protected GWDTE habitat types in
different periods and different hydrologic spatial locations. Results
reveal a decrease in the area of GWDTE over the last 200 years. We
attribute this to different human interventions that through e.g.,
drainage, have impacted the low-lying landscape throughout history. We
further conclude that downstream parts of the river network have been
exposed to less GWDTE habitat loss than upstream ones. This indicates
that upstream river valleys are more vulnerable to GWDTE decline.
Therefore, as a management measure, caution should be exercised when
designing these areas for agriculture activities using artificial
drainage and groundwater abstraction since this may lead to further
decline. In contrast, there is a higher potential for establishing
constructed wetlands or rewetting peatlands to restore balance.
Safety, tolerability, and serum/tear pharmacokinetics of human recombinant epidermal growth factor eyedrops in healthy subjects
Authors: Yoo Hyounggyoon , Yoon Seonghae , Jang In-Jin , Yu Kyung-Sang , Hyon Joon Young , Hwang Jungi , Hwang Inyoung , Sunwoo Jung , Chung Jae-Yong
Published: June 2022

Aims: The aim of this study was to evaluate the safety/tolerability, and
pharmacokinetics (PKs) of rhEGF eyedrops after administration of a
single and multiple doses in healthy subjects. Methods: A phase 1,
randomized, double-blind, placebo-controlled, and single ascending dose
(SAD) and multiple ascending dose (MAD) study were conducted in 3 dose
groups (10, 50, and 100 μg/mL). The subjects randomly received rhEGF
eyedrops or their placebo in a 3:1 ratio. Serial blood and tear samples
for PK analysis were collected up to 36 h and 180 h post-dose in SAD and
MAD study, respectively. In addition, the serum and tear EGF
concentrations were measured. Immunogenicity evaluations were conducted
using serum anti-EGF antibody level. Results: A total of 50 subjects
were enrolled and 48 subjects completed the study. Adverse drug
reactions were mild and transient. There were no serious adverse events
in this study. The tear EGF concentrations rapidly increased and
returned to baseline after 4 hours without serum EGF level change after
the administration of rhEGF eyedrops. Conclusion: rhEGF eyedrops were
safe and well-tolerated in healthy subjects in a dose range of 10-100
μg/mL, which indicated it was suitable for further studies for corneal
injury patients.
Elemental composition of selected lichen species growing on the Balkan Peninsula
Authors: Tosic Snezana , Pavlovic Aleksandra , Dimitrijevic Ivana , Zlatanovic Ivana , Mitic Violeta , Stojanovic Gordana
Published: June 2022

The amount of nineteen elements in eleven different lichen species, six fruticose (Bryoria capillaris, Bryoria fuscescens, Cladonia rangiformis, Ramalina capitata, Usnea chaetophora and Evernia prunastri) and five foliose (Hypogymnia tubulosa, Lobaria pulmonaria, Peltigera horizontalis, Umbilicaria cylindrica and Umbilicaria crustulosa) from five natural areas of the Balkan Peninsula (Serbia and Bulgaria) were determined by using inductively coupled plasma optical emission spectrometry (ICP-OES). Among macronutrients, the highest content was observed for Ca and K, while Mg and Na were represented in the smallest amount. Fe, Mn, Zn and Ba were the most abundant trace elements in contrast to Cd and Co, whose concentration? w?re the lowest.
CHCHD10 Modulates Thermogenesis of Adipocytes by Regulating Lipolysis
Authors: Ding Meng , Ma Yin-jun , Du Ruo-qi , Zhou Wei-yu , Dou Xin , Yang Qi-qi , Tang Yan , Qian Shu-wen , Liu Yun , Pan Dong-ning , Tang Qi-Qun , Liu Yang
Published: June 2022

Brown and beige adipocytes dissipate energy in a nonshivering thermogenesis manner, exerting beneficial effects on metabolic homeostasis. CHCHD10 is a nuclear-encoded mitochondrial protein involved in cristae organization; however, its role in thermogenic adipocytes remains unknown. We identify CHCHD10 as a novel regulator for adipocyte thermogenesis. CHCHD10 is dramatically upregulated during thermogenic adipocyte activation by PPARγ-PGC1α and positively correlated with UCP1 expression in adipose tissues from humans and mice. We generated adipocyte-specific Chchd10 knockout mice (Chchd10-AKO) and found that depleting CHCHD10 leads to impaired UCP1-dependent thermogenesis and energy expenditure in the fasting state, with no effect in the fed state. Lipolysis in adipocytes is disrupted by CHCHD10 deficiency, while augmented lipolysis through ATGL overexpression recovers adipocyte thermogenesis in Chchd10-AKO mice. Consistently, overexpression of Chchd10 activates thermogenic adipocytes. Mechanistically, CHCHD10 deficiency results in the disorganization of mitochondrial cristae, leading to impairment of oxidative phosphorylation complex assembly in mitochondria, which in turn inhibits ATP generation. Decreased ATP results in downregulation of lipolysis by reducing nascent protein synthesis of ATGL, thereby suppressing adipocyte thermogenesis. As a result, Chchd10-AKO mice are prone to develop high-fat diet–induced metabolic disorders. Together, our findings reveal an essential role of CHCHD10 in regulating lipolysis and the thermogenic program in adipocytes.
CHCHD10 Modulates Thermogenesis of Adipocyte by Regulating Lipolysis
Authors: Ding Meng , Ma Yin-jun , Du Ruo-qi , Zhou Wei-yu , Dou Xin , Yang Qi-qi , Tang Yan , Qian Shu-wen , Liu Yun , Pan Dong-ning , Tang Qi-Qun , Liu Yang
Published: June 2022

  

Brown and beige adipocytes dissipate energy in a non-shivering thermogenesis manner, exerting beneficial effects on metabolic homeostasis. CHCHD10 is a nuclear-encoded mitochondrial protein involved in cristae organization; however, its role in thermogenic adipocytes remains unknown. Herein, we identify CHCHD10 as a novel regulator for adipocyte thermogenesis. CHCHD10 is dramatically upregulated during thermogenic adipocytes activation by PPARγ-PGC1α, and positively correlated with UCP1 expression in the adipose tissues from human and mice. We generate adipocyte-specific Chchd10 knockout mice (Chchd10-AKO) and find that depleting CHCHD10 leads to impaired UCP1-dependent thermogenesis and energy expenditure in the fasting state, with no effect in fed state. Lipolysis in adipocytes is disrupted by CHCHD10 deficiency, while augmented lipolysis via ATGL overexpression recovers adipocyte thermogenesis in Chchd10-AKO mice. Consistently, overexpression of Chchd10 activates thermogenic adipocytes. Mechanistically, CHCHD10 deficiency results in the disorganization of mitochondrial cristae, leading to impairment of oxidative phosphorylation complex assembly in mitochondria, which in turn inhibits ATP generation. Decreased ATP results in downregulation of lipolysis by reducing nascent protein synthesis of ATGL, thereby suppressing adipocyte thermogenesis. As a result, Chchd10-AKO mice are prone to develop high-fat diet-induced metabolic disorders. Together, our findings reveal essential role of CHCHD10 in regulating lipolysis and thermogenic program in adipocytes.
REVERBERAÇÕES DA SEMANA DE 1922
Authors: Rodrigues Rodrigo , Da Silva  Delfino Duarte Ana Helena da Silva  Delfino Duarte
Published: June 2022

Um século depois da tão polêmica e emblemática Semana de Arte Moderna de 1922, a atuação do artista Di Cavalcanti, se revela particularmente importante na medida em que sua investigação pictórica, comprometida com uma nova pesquisa plástica, aliada a outras tradições culturais brasileiras, trazia ao lume o grande debate intelectual sobre um projeto nacional. Considerando a Semana de 22 na conjuntura de um amplo e complexo processo de transformação cultural que ocorria no vasto território brasileiro, o qual não pode ser circunscrito exclusivamente a um fenômeno eminentemente urbano e paulistano, diretamente conectado ao crescimento industrial, à migração maciça de estrangeiros e à urbanização que caracterizavam a cidade de São Paulo na década de 1920, Di Cavalcanti pode ser entendido como figura central para pensar as reverberações desse fenômeno moderno nas décadas seguintes e inclusive nas implicações e releituras críticas que empreendemos transcorridos cem anos de seu acontecimento.
Mulher independente ou dona de casa?
Authors: Leal Francisca Mansilla
Published: June 2022

Até 2020, as marcas de produtos investirão metade de seu orçamento de marketing de publicidade na Internet, o que reflete a importância que esse meio on-line está adquirindo no futuro. A Internet não é apenas um novo canal de comunicação para publicidade, mas também tem a capacidade de moldar comportamentos sociais, oferecendo imagens de mulheres e homens como estereótipos que podem influenciar futuras gerações de consumidores. A propaganda tem o poder de transformar a opinião pública, ajudando e encorajando, por meio de suas mensagens, que os membros de um país são equitativos em termos de gênero.
Imaginário coletivo sob as palafitas do dique da Vila Gilda
Authors: Bocaiuva Ribas Mariana
Published: June 2022

A pesquisa tem como objetivo identificar os principais elementos que compõem o imaginário coletivo dos moradores do Dique da Vila Gilda - a maior favela de palafitas da América Latina (que abriga 20 mil pessoas), na Zona Noroeste do município de Santos, litoral do Estado de São Paulo. O imaginário é composto da massificação de significados gerados, sobretudo pela mídia hegemônica, para temas do cotidiano local como "violência", "lixo" e "políticas públicas", por meio de entrevistas e de produções artístico-culturais dos moradores locais, assim como refletir sobre a produção jornalística sobre o bairro. Agrega-se à pesquisa o aprofundamento de estudos sobre a temática do imaginário com base em obras de teóricos sobre o tema. Dessa forma, será possível contribuir para o desenvolvimento dos veículos de comunicação propostos pelo Projeto “Redic” (Rede de Informação Comunitária) levado a cabo pelo o grupo de pesquisa "Mediações Telemáticas" (Mediatel), do curso de Jornalismo da PUC-SP, para a comunidade do Dique da Vila Gilda. O Redic tem o objetivo de criar e manter dois veículos de comunicação comunitários locais: um informativo digital intitulado "Jornal da Maré", uma Radioweb Comunitária, com o nome de "Rádio Palafita".
FUNERAL RITES OF KET AND NAVAJO INDIANS: EXPERIENCE OF HISTORICAL AND ETHNOGRAPHIC COMPARISON
Authors: Николаев Вячеслав Романович
Published: June 2022

В статье проведен сравнительный анализ погребально-поминальной обрядности кетов (представителей енисейской языковой семьи) и индейцев навахо (представителей языковой семьи на-дене) с целью выявления в этих обрядах каких-либо культурных сходств и связей для сбора данных, позволяющих впоследствии анализировать характер самих этих связей. В результате автором статьи были получены выводы о том, что среди характеристик в погребально-поминальном обряде кетов и индейцев навахо есть как существенные (захоронения на лабазе и на дереве, объяснение смертности человека, ориентация умершего), так и менее существенные сходства. Некоторые элементы сходства в погребально-поминальных обрядах сравниваемых этносов позволяют (с большой осторожностью) оценить имеющиеся черты сходства как носящие характер культурно-генетических, что может стать неким дополнительным аргументом в пользу теории о родстве индейцев на-дене и енисейцев.

The study is carried out a comparative analysis of the memorial and funeral rites of the Indians of the Na-Dene (Navajo) group and the Yenisei (Kets). The purpose of this study is to conduct a comparative analysis of ethnographic material in order to identify any cultural similarities and parallels in the memorial and funeral rites of the Navajo Indians and Kets and to collect data that would allow to analyze the nature of these ties themselves afterwards. As a result, the author of the article reached the conclusions that among the characteristics in the funeral ritual of the Kets and Navajo Indians there are both principal (the burials in a warehouse and on a tree, an explanation of human mortality and the orientation of the deceased in an eastern direction) and insignificant similarities among the characteristics in the funeral rituals of the Kets and Navajo Indians. There are cultural ties in memorial and funeral rites that allow (with great caution) to evaluate the existing similarities as cultural and genetic, which may become an additional argument in favor of the theory of the Na-Dene Indians’ and the Yenisei’s kinship.
ATTITUDES, CONSUMPTION PATTERNS AND CONSUMER SATISFACTION OF KETJE COFFEE IN THE CITY OF BANDAR LAMPUNG
Authors: Lestari Rizki Tri , Haryono Dwi , Adawiyah Rabiatul
Published: June 2022

This study aims to analyze attitudes, consumption patterns, and consumer satisfaction of Kopi Ketje in Bandar Lampung City. This study uses a survey method which was carried out at 16 branches of Kopi Ketje in Bandar Lampung City in January 2022 with 50 respondents. The analytical tools used are Fishbein multi-attribute, qualitative descriptive analysis, and the Customer Satisfaction Index (CSI). The consumers who made the most purchased were women aged 17-25 years as many as 34 consumers. The number of family members of Kopi Ketje consumers are mostly 4 people and the majority(82%) of Kopi Ketje consumers is students. Most of the consumer respondents (46%) earn an income of IDR 500.001.00 - IDR 1.000.000,00 per month. The results of the study show that the total attitude value of consumers is 90.18 with a fairly good category. Kopi Ketje consumers usually buy and consume Kopi Ketje drinks as much as 250-549 ml per transaction (66%) with most of the frequency of purchasing Kopi Ketje as much as 1-3 times per month (88%). The variation of Kopi Ketje that is much preferred by consumers is the ndeso coffee variation (42%) with most of the reasons for enjoying the taste (46%), however, most of the other coffee drink brands that are often purchased by consumers are Kopi Janji Jiwa (58%) because of the taste. Halal assurance is considered very important by consumers (86%). The CSI value was obtained at 82.29 percent (very satisfied).Keywords: attitude, coffee, consumption pattern, satisfaction.
KETAHANAN PANGAN RUMAH TANGGA PETANI KELAPA SAWIT SWADAYA DI KABUPATEN TULANG BAWANG
Authors: Aisy Alifia Marsa , Haryono Dwi , Ismono Raden Hanung
Published: June 2022

The aims of this research are to analyze the level of food security, the factors that affect the level of food security, and efforts to increase the level of food security of palm oil farmer households (POFH). The research was conducted using a survey method in Tulang Bawang Regency by involving 67 respondents from POFH who were chosen by a simple random sampling. The results of the research showed that 47.76 percent of POFH were categorized as the most secure of food, 29.85 percent as less secure, 20.90 percent as vulnerable, and 1.49 percent as food insecure. The factors that positively affect household food security were household income, formal education level of household head, and ethnicity.  The factor that negatively affect household food security was the the number family members. The efforts to increase the level of food security by Government were monitoring the stock of rice, drafting food balance, Programs called Pengembangan Usaha Pangan Masyarakat (PUPM), Kawasan Rumah Pangan Lestari (KRPL) and Modal Pengembangan Pangan Pokok Lebel (MP3L). The efforts of palm oil farmer households were owing groceries (47.50%), do outside work of palm oil farmer (50.62%), and changing dietary habit (1.88%). Key words: cross-classification, food security, palm oil households.
PERAN GENDER, PENDAPATAN DAN KESEJAHTERAAN SUBJEKTIF RUMAH TANGGA PETANI KOPI DI KECAMATAN SUMBEREJO KABUPATEN TANGGAMUS
Authors: Fitri Rama Ayu , Prasmatiwi Fembriarti Erry , Riantini Maya
Published: June 2022

This study aims to analyze gender roles, household income, subjective well-being and correlation between gender roles and subjective well-being of coffee farmer households in Sumberejo District, Tanggamus Regency.  This research is conducted by a survey method.  The location is chosen purposively in Sumbermulyo Village and Margoyoso Village, for the villages are the center of coffee production in Sumberejo District.  The samples in this research are 67 coffee farmers.  The samples determined by simple random sampling method.  Data were collected in March-April 2019 and analyzed by descriptive qualitative analysis, descriptive quantitative analysis and Chi-Square test.  The results of this research showed that gender roles in domestic activities and public activities were categorized as low and gender roles in social activities were categorized as moderate.  The average household income of coffee farmers was IDR39,467,773.88 per year.  The most contributed income was derived from coffee farming activities.  The subjective well-being was categorized as high. There was a significant relationship between gender roles and subjective well-being.Key words: coffee farming, gender roles, income, subjective well-being
VALUASI EKONOMI DENGAN METODE TRAVEL COST PADA WISATA TAMAN KEANEKARAGAMAN HAYATI KABUPATEN MESUJI
Authors: Novita Susan , Abidin Zainal , Kasymir Eka
Published: June 2022

This research aims to analyze visitor satisfaction on tourism facilities and infrastructures, travel cost, factors that affect the number of visits, and economic value of Taman Kehati in Mesuji Regency.  This research used a survey method involving 65 respondents.  Data were collected in December 2019.  The first objective was analized using likert scale analysis, the second objective used travel cost method, the third objective used multiple linear regression analysis, and the fourth objective used consumer surplus analysis.  The study suggests that visitors were satisfied with facilities and infrastructure provided by Taman Kehati, travel cost was IDR165.614 per individual with the highest cost allocated for consumption, which was IDR101.656,72 or 61 percent of total travel cost.  The factors affecting the number of visits to Taman Kehati included age, income, travel cost, travel time, day of the visit, and conditions of the park.  The economic value of Taman Kehati is IDR993.850.777.736 per year. Key words: economic value, travel costs, visitor satisfaction.
Persepsi Masyarakat Nagari Kasang terhadap Pengadaan Tanah Pembangunan Jalan Tol Padang Pekanbaru (Padang-Sicincin)
Authors: Fahmi Andra , Eka Putri Nora
Published: June 2022

From the field review, this study aims to determine the opinion of Kasang Nagari residents on land acquisition for the construction of the Padang-Pekanbaru (Padang-Sicincin) Toll Road. This analysis is the background of the intensity of policy makers in providing this land properly so that no party feels betrayed, especially residents. However, the application for land acquisition in Nagari Kasang is still in the form of the low price offered by the government to the residents, the unsuccessful negotiation of land prices by the policy authorities with the community, and residents whose lands have been evicted. in danger of running out of livelihood. This research is qualitative with descriptive procedures that have been carried out in Nagari Kasang, Padang Pariaman Regency, which was attacked in the construction of the Padang-Pekanbaru toll road (the Padang-Sicincin section). The results of this study indicate that the residents' assumptions have been accepted and interpreted well, land acquisition has been attempted in a structured manner, and compensation for land losses has been explained to residents
Analisis Pemanfataan Dana Desa dalam Pemberdayaan Masyarakat dan Pembangunan Berkelanjutan
Authors: Wima Putri Nada , Frinaldi Aldri
Published: June 2022

This study aims to determine the results of the use of village funds in Lewalu village related to community empowerment and sustainable development and whether the use of village funds is in accordance with the plan or not. This research was carried out using a qualitative descriptive approach in which data collection was based on the factors that became the main supporters of the research object. In this study, the withdrawal of informants was based on a purposive sampling technique which was based on the main criteria, namely that they must be the people of Lewalu Village, regardless of their role or position in the village. Thus data collection is done by means of interviews, observation and documentation. Data analysis is done by collecting data, reducing data, presenting data, and drawing conclusions. Then the validity of this data was tested by triangulation of sources which was then analyzed. The use of village funds in community empowerment and sustainable development found the research results, namely; the use of village funds in Lewalu Village related to community empowerment and sustainable development has been carried out by the village government in accordance with the stages of village financial management as stated in the Minister of Home Affairs Regulation No. 20 of 2018. Utilization of village funds in Lewalu Village provides many benefits for the community. . With the existence of village funds in Lewalu Village, it has provided improvements in Lewalu Village such as increasing physical buildings and infrastructure and increasing community productivity through empowerment programs that have been carried out.
Efektivitas Pelayanan Rumah Pangan Kita (RPK) di Perusahaan Umum Badan Urusan Logistik (Perum Bulog) Kantor Cabang Bukittinggi
Authors: Ridha Muhammad , Mubarak Adil
Published: June 2022

This study aims to determine the effectiveness of the Rumah Pangan Kita (RPK) service at the General Logistics Affairs Agency (Perum BULOG) Bukittinggi Branch Office. This research was carried out using a qualitative descriptive approach in which data collection was based on the factors that became the main supporters of the research object. In this study, the withdrawal of informants was based on a purposive sampling technique which was based on the main criteria, namely that they must be the people of the City of Bukittinggi. This data collection is done by means of interviews, observation, and documentation. Data analysis is done by collecting data, reducing data, presenting data, and drawing conclusions. Then the validity of this data was tested by triangulation of sources which was then analyzed. Based on the findings, it can be concluded that the Rumah Pangan Kita program carried out by Perum BULOG at the Bukittinggi Branch Office has been effectively carried out through the RPK companion application. The obstacles experienced by partners are delays in payments exceeding the compensation provided by Perum Bulog
Examination of the Pre-service Teachers’ Experiences and Perceptions on Teaching Practices: English Language Teaching Case
Authors: KARSLİ Veysel , YAĞIZ Oktay
Published: June 2022

This study aims to evaluate the pre-service teachers’ experiences and perceptions on teaching practices provided within an internship program carried out at a major state university in Turkey in a holistic way from various aspects. The participants of the study were 65 pre-service teachers studying in the English Language Teaching department at a state university in Turkey. For this purpose, in the study, an explanatory mixed-methods research design was used. A Likert scale questionnaire was conducted with the pre-service teachers to collect quantitative data. Then a semi-structured interview was conducted with eight pre-service teachers to support the quantitative data with qualitative data. The results show that the teaching practice offered within the scope of the internship program is effective as it responds to the needs of pre-service teachers in terms of professional development and mentoring support regarding their teaching professional skills. However, the findings also show that according to the pre-service teachers, there are some issues such as the length of the teaching practice, the inadequacy of mentorship support, organizational problems, and the limited freedom given during teaching practice need to be considered. Finally, the study concludes by presenting some recommendations in line with the results to improve the quality of the teaching practice provided to pre-service teachers in Turkey.
Investigating the Importance of Conversational Implicature and Violation of Maxims in Daily Conversations
Authors: Rabaab Elmahady Musa Osman , subaiah Sarvanan , Bahia Afrin Mohammed Sharifa
Published: June 2022

According to linguistic theory, conversational Implicature (CI) is the original intent of the speech expressed by a speaker. The assumption is that both the speaker and the receiver understand and respect the communication rules. In conversation theory, this is the significant component that has been the subject of discussion. This study investigates the importance of CI in various contexts of daily conversations. The focus of this study is to identify the violation of Grice’s theory in the conversation. There is a shortcoming in literature to investigate CI in everyday conversations. Moreover, some studies focussed on specific discussions, which led to a literature gap. The study’s outcome will assist researchers in exploring new ideas in conversational implicatures. In addition, it reveals the shortcomings of the usage of implicatures. In this study, the researchers analyzed a set of 77 daily conversations. The study showed that context is critical in determining the meaning of a person’s thoughts. In addition, the finding suggests that particularized CI are primarily employed in daily conversations.
PENGEMBANGAN MEDIA PEMBELAJARAN INTERAKTIF MENGGUNAKAN LECTORA INSPIRE PADA MATA PELAJARAN INSTALASI PENERANGAN LISTRIK KELAS XI TEKNIK INSTALASI TENAGA LISTRIK DI SMK NEGERI 1 PERCUT SEI TUAN
Authors: Sihombing Apri W , Sutopo Adi
Published: June 2022

Abstrak: Penelitian ini bertujuan untuk mengembangkan multimedia pembelajaran. Multimedia pembelajaran termasuk hal yang sangat penting dalam proses pembelajaran, multimedia pembelajaran yang baik sangat efektif digunakan dalam proses belajar mengajar. Peneliti mencoba mengembangkan multimedia pembelajaran interaktif yang dapat digunakan dalam bentuk CD interaktif, menggunakan beberapa software yang terdiri dari Lectora Inspire, Adobe Photoshop CS5, Bandycam, dan EKTS. Bertujuan untuk memudahkan peserta didik dalam memahami pelajaran dan juga memudahkan pendidik dalam menyampaikan pelajaran. Multimedia pembelajaran pada penelitian ini menggunakan model desain Borg and Gall yang diadaptasi oleh Sugiyono.Sasaran penelitian ini adalah Dosen Ahli Universitas Negeri Medan. Pengujian terhadap multimedia interaktif oleh validator media dan validator materi menunjukkan bahwa multimedia pembelajaran yang dihasilkan baik pada validasi materi dengan skor rata-rata 4,6 dan untuk validasi media dengan skor rata-rata 4,3. Maka diperoleh kesimpulan media yang dikembangkan layak untuk digunakan. Kata Kunci: Pengembangan  Media Interaktif, Software Lectora, Instalasi Penerangan Listrik Abstract: This research aims to develop multimedia learning. Multimedia learning is very important in the learning process, good multimedia learning is very effective in the teaching and learning process. Researchers try to develop interactive learning multimedia that can be used in the form of interactive CDs, using several software consisting of Lectora Inspire, Adobe Photoshop CS5, Bandycam, and EKTS. Aims to make it easier for students to understand the lesson and also make it easier for educators to deliver lessons. Multimedia learning in this study uses the Borg and Gall design model which was adapted by Sugiyono. The target of this research is an Expert Lecturer at the State University of Medan. Testing of interactive multimedia by media validators and material validators shows that the learning multimedia produced is good for material validation with an average score of 4.6 and for media validation with an average score of 4.3. Then it can be concluded that the developed media is feasible to use. Keywords: Interactive Media Development, Lectora Software, Electrical Lighting Installation
PENGEMBANGAN BAHAN AJAR ENSIKLOPEDIA DIGITAL PADA MATA KULIAH SEJARAH INDONESIA MASA HINDU BUDHA
Authors: Diansyah Arfan , Tanjung Flores , Nasution Abd Haris
Published: June 2022

Pengembangan Bahan Ajar Ensiklopedia Digital Dejarah Indonesia Masa Hindu Budha merupakan konsekuensi yang harus diambil dalam menyikapi perkembangan teknologi informasi. Tujuan dari penelitian ini adalah menghasilkan bahan ajar digital dalam mata kuliah sejarah Indonesia periode Hindu Budha. Penelitian ini menggunakan model pengembangan ADDIE (Analysis, Design, Develop, Implement and Evaluate) oleh Dick and Carry dengan menghilangkan tahap evaluasi. Subjek penelitian terdiri dari ahli materi, ahli media, dan mahasiswa program studi pendidikan sejarah Universitas Negeri Medan. Teknik analisis data menggunakan deskriptif kuantitatif dan kualitatif. Teknik pengumpulan data menggunakan kuesioner dan wawancara. Teknik analisis data dilakukan dengan membandingkan data dengan jumlah yang diharapkan dan persentase yang diperoleh. Hasil penelitian menunjukkan persentase uji kelayakan ahli materi tahap 1 sebesar 72,6%, hal ini menunjukkan bahwa bahan ajar yang dikembangkan dalam kategori cukup layak. Persentase uji kelayakan ahli materi tahap 2 sebesar 88,6%, hal ini menunjukkan bahwa bahan ajar yang dikembangkan layak. Persentase kelayakan hasil pengujian ahli media sebesar 88%, hal ini menunjukkan bahwa produk yang dikembangkan layak. Hasil penilaian siswa rata-rata dari kelompok kecil adalah 4,2. Persentase kelayakan hasil penilaian siswa kelompok kecil adalah 84%. Hasil tersebut menunjukkan bahwa bahan ajar yang dikembangkan layak untuk digunakan. Hasil penilaian siswa rata-rata dari kelompok besar adalah 4,1. Persentase kelayakan hasil penilaian siswa kelompok besar adalah 82%. Hasil tersebut menunjukkan bahwa bahan ajar yang dikembangkan layak untuk digunakan.
PERKEMBANGAN WISATA BAHARI DI DESA TUAPEJAT KECAMATAN SIPORA UTARA KABUPATEN KEPULAUAN MENTAWAI
Authors: Erivera Rospita , Yulia Refni , Ersi Livia
Published: June 2022

Tuapejat merupakan salah satu Desa yang ada di Kabupaten Kepulauan Mentawai dan merupakan salah satu Desa induk dari desa lainnya yang berada di pusat Kabupaten. Desa Tuapejat memiliki  potensi wisata alam yang menarik seperti wisata wisata pantai, surfing, menyelam. Potensi  yang dimiliki Desa Tuapejat mengalami peningkatan kunjungan wisatawan setiap bulan atau setiap tahun mengalami peningkatan. Tujuan Penelitian ini untuk mengetahui perkembangan wisata bahari khususnya di Desa Tuapejat Kabupaten Kepulauan Mentawai. Metode yang digunakan adalah metode penelitian sejarah. Hasil penelitian ini diuraikan bahwa wisata bahari di Desa Tuapejat terdiri dari beberapa, antara lain Wisata pantai, wisata menyelam, wisata ombak Telescope. Wisata ini dikategorikan sebagai wisata bahari. Wisata pantai merupakan salah wisata yang paling banyak diminati para pengunjung  wisata yang datang di Tuapejat. Selain untuk  menikmati pantai wisatawan yang berkunjung juga dapat menikmati ombak. Wisatawan yang datang seperti wisatawan mancanegara sangat senang menikmati ombak dengan berselancar. Secara keseluruhan khususnya wilayah Sipora Utara objek wisata yang dapat dikunjungi yaitu Dermaga  Tuapejat, Pantai jati, Air Terjun Pajujurung, Taman Patung Sikerei, Pulau Umat Siteu dan Pulau  Awera. Namun tidak terlepas peran dari masyarakat dan pemerintah  terhadap perkembangan wisata di DesaTuapejat. Oleh karena itu kepada Pemerintahan Daerah agar dapat  membuat aturan-aturan dan evalusi agar pengembangan objek wisata bahari di Desa Tuapejat lebih berkembang.
PERAN GURU SEJARAH DALAM MENGUATKAN NASIONALISME PADA PESERTA DIDIK KELAS XI IPS DI SMAN 2 SUNGAI LIMAU
Authors: Prayogi Prayogi , Husnita Liza , Kaksim Kaksim
Published: June 2022

Penelitian ini dilatarbelakangi oleh rasa nasionalisme siswa di SMA Negeri 2 Sungai Limau. Guru mata pelajaran sejarah menerangkan tidak semua siswa yang mempunyai rasa nasionalisme, fenomena yang terlihat seperti tidak mengikuti upacara Bendera, masih berbincang dengan teman sebelah saat upacara bendera, membuang sampah sembarang, kurang menghargai guru, kurang tegur sapa, berkelahi di lingkungan sekolah, serta main games, hal tersebut menunjukkan kurangnya kedisiplinan siswa, dan karakter siswa menjadi tidak peduli kepada pendidikan, sehingga ini berdampak kepada kurangnya rasa nasionalisme. Penelitian ini dilakukan dengan pendekatan kualitatif menggunakan metode deskriptif kualitatif. Hasil penelitian ini menunjukkan bahwa peran guru sejarah dalam menguatkan nasionalisme pada peserta didik kelas XI IPS di SMA Negeri 2 Sungai Limau ditanamakannya nilai karakter, tanggung jawab, jujur kepada peserta didik, dengan cara diskusi, kuis, Tanya jawab, selama proses pembelajaran berlangsung. Mulai dari kegiatan pembukaan, kegiatan inti, sampai pada kegiatan penutupan pembelajaran. Adapun peran guru dalam penguratan rasa nasionalisme kepada siswa SMA Negeri 2 Sungai Limau terbagi kepada tiga tahap yaitu, dalam tahap pembuatan Perencanaan Pembelajaran, implementasi dan tahap evaluasi hasil belajar. Berdasarkan hasil penelitian, dapat disimpulkan bahwa peran guru sejarah dalam membangun rasa nasionalisme dikelas XI SMA Negeri 2 sungai limau sudah berjalan dengan sebagaimana semestinya, banyak dari siswa kelas XI IPS sudah mengetahui pentingnya mempelajari serta membangun “rasa nasionalisme”.
PROSEDUR PENYELESAIAN LAPORAN KASUS MAL-ADMINISTRASI OLEH OMBUDSMAN RI PERWAKILAN PROVINSI SUMATERA BARAT
Authors: Fatmawati Fatmawati , Isnaini Isnaini , Yuhelna Yuhelna
Published: June 2022

Buruknya pelayanan Publik disebabkan oleh diskriminasi pelayanan, tidak adanya kepastian biaya dan waktu pelayanan dan rendahnya tingkat kepuasan masyarakat terhadap pelayanan public. Untuk mewujutkan penyelenggaraan negara dan pemerintah yang berkualitas, bebas dari praktek Maladminstrasi maka dipandang perlu adanya pengawasan ektrenal seperti Ombudsman RI. Tujuan penelitian yakni mendeskripsikan Keberadaan Ombudsman Republik Indonesia merupakan Lembaga negara yang bersifat mandiri (Independent) artinya tidak berada di bawah kendali presiden dan tidak memiliki hubungan organik dengan lembaga negara dan instansi pemerintah lainnya. Hasil penelitian ini yakni Kehadiran Ombudsman RI Perwakilan Sumatera Barat diharapkan mampu mewujudkan penyelenggaran pemerintah daerah yang bersih, demokratis, transparan, dan akuntabel serta bebas dari Korupsi, Kolusi dan Nepotisme, penyalahgunaan kekuasaan atau jabatan, dan tindakan sewenang-wenang serta membantu setiap warga masyarakat untuk memperoleh pelayanan yang baik, berkualitas, profesional dan proporsional. Dengan Teori institusi merupakan suatu teori yang mempelajari bagaimana organisai-organisasi dapat meningkatkan kemampuannya untuk tumbuh dan bertahan hidup (serevise) dalam suatu lingkungan yang serba kompetitif dengan menjadi terpercaya (legitimate) di mata para stakeholdersnya. Tentunya, nilai-nilai normatif organisasi seperti efesiensi, efektivitas dan ekonomis sebagai landasan dalam pencapaian tujuan organisasi perlu menjadi perhatian untuk meningkatkan kemampuan kompetisinya agar mampu bertahan hidup dalam era globalisasi ini. Oleh karena itu tulisan ini akan mengupas tuntas mengenai Teknik Monitoring Dan Evaluasi (Monev) Dalam Rangka Penyelesaian Kasus Mal-Administrasi Dilembaga Ombudsman RI Perwakilan Provinsi Sumatera Barat.
BENTUK MODAL SOSIAL PADA PELAKU USAHA INDUSTRI BATU BATA DI KORONG PALEMBAYAN NAGARI SINTUK KECAMATAN SINTUK TOBOH GADANG
Authors: Santi Nova Agus , Rahmadani Sri , Isnaini Isnaini
Published: June 2022

Modal sosial terjadi pada unsur industri yang menciptakan kesadaran kolektif. Kesadaran kolektif didasarkan pada kepercayaan dan kesetiakawanan meliputi seluruh kepercayaan dan perasaan bersama orang kebanyakan dalam sebuah masyarakat akan membentuk suatu system yang tetap yang punya kehidupan sendiri. Industri merupakan kegiatan ekonomi yang bertujuan untuk meningkatkan kesejahteraan masyarakat dengan memanfaatkan sumber daya alam, sumber daya manusia, dan dana,. Penelitian ini bertujuan untuk mendeskripsikan bentuk modal sosial pada pelaku usaha industri batu bata di Korong Palembayan Nagari Sintuk Kecamatan Sintuk Toboh Gadang Pendekatan yang dilakukan dalam penelitian ini adalah pendekatan kualitatif dengan jenis penelitian kualitatif deskriptif. Jenis data yang digunakan dalam penelitian ini yaitu data sekunder dan data primer. teknik pengumpulan data yang digunakan yaitu observasi, wawancara, dan studi dokumen. Berdasarkan hasil penelitian terdapat beberapa modal sosial pada pelaku usaha industri batu bata di Korong Palembayan Nagari Sintuk Kecamatan Sintuk Toboh Gadang yaitu: 1) modal sosial yang mengikat (social bounding), dan 2) Modal Sosial Menjembatani (bridging social capital).
Insomnia Audio Therapy Mobile Application with Music Recommender System
Authors: Mohamad Zamani Nur Azmina , Omar Nasiroh , Huda Azmi Nur Damira
Published: June 2022

With the quick advancement of Internet and artificial intelligence technologies, development of a robust and accurate music recommendation system has become an important issue in the field of music information retrieval. Music recommendation system has been widely used in many real-life applications, including in the health domain as an alternative of therapies. This paper presents the research design and implementation of music recommendation system that possible to be used as an insomnia audio therapy in a mobile application platform. The research focused on investigating the performances of three machine learning algorithms namely Random Forest, Decision Tree and Support Vector Machine to be selected as the music recommendation tool. For the machine learning training and testing purposes, data was collected based on the simulated run of the proposed insomnia audio therapy mobile application. The results indicated that Random Forest performed as the best machine learning algorithm in predicting the relevant music. The proposed mobile application with machine learning music recommender system will provide a basis for the realization of intelligent music therapy in treating insomnia disorder patients as well as in other music applications.
SANITASI MAKANAN DAN POLA MAKAN DI PONDOK PESANTREN SUNAN DRAJAD LAMONGAN
Authors: Lestari Marselli Widya , Winarningsih Wiwik
Published: June 2022

Berdasarkan survey pada 10 santri Pondok Pesantren Sunan Drajad, Lamongan, 9 diantaranya tidak memiliki pola makan yang baik. Hal-hal ini meningkatkan risiko seseorang menjadi gemuk, overweight, bahkan obesitas. Berdasarkan analisis situasi diatas, penyuluhan mengenai pola hidup dan makan yang sehat sangat diperlukan untuk mencegah resiko penyakit yang tidak diinginkan. Pengabdian masyarakat ini dilakukan dengan metode penyuluhan kepada siswa sekolah menengah atas yang dihadiri oleh tenaga kesehatan yang berasal dari dokter pengajar dan mahasiswa kedokteran Universitas Nahdlatul Ulama Surabaya. Hasil yang didapatkan cukup memuaskan, peserta sangat antusias, dan aktif menjawab pertanyaan yang diberikan. Dilihat dari feedback peserta dapat dikatakan kegiatan penyuluhan ini berhasil. Dari hasil kegiatan yang dilakukan, dapat disimpulkan bahwa pengetahuan untuk meningkatkan kesadaran dalam berperilaku hidup sehat dan menerapkan pola makan yang sehat sudah diterima dengan baik oleh peserta. Program ini diharapkan dapat dilakukan secara berkala sehingga dapat terus menambah wawasan masyarakat mengenai kesehatan.
SOSIALISASI LITERASI KESEHATAN TENTANG PENCEGAHAN DAN PENANGGULANGAN KANKER SERVIKS BAGI REMAJA DI KAB.BANDUNG BARAT
Authors: Hadisiwi Purwanti , Arifin Hadi Suprapto
Published: June 2022

Tingginya angka penderita kanker serviks antara lain disebabkan oleh kurangnya kesadaran dalam upaya pencegahan dan penanggulangan kanker serviks. Kanker serviks yang merupakan “the silent killer” adalah penyakit mematikan yang gejalanya baru muncul setelah 15-20 tahun terinfeksi, membuat perempuan tidak menyadari bahayanya penyakit ini. Oleh karena itu, salah satu cara dalam pencegahannya adalah dengan memberikan sosialisasi literasi kesehatan tentang kanker serviks kepada khalayak remaja. Remaja sebagai sasaran yang paling tepat untuk diberikan sosialisasi literasi kesehatan tentang pencegahan kanker serviks tersebut. Hal ini sebagai upaya pencegahan sejak dini agar remaja peduli pada kesehatan reproduksinya. Kegiatan PKM ini dilakukan di SMAK Cimareme, Padalarang, kabupaten Bandung Barat. Metode sosialisasi dilakukan dengan pemberian ceramah, pemutaran video tentang kanker serviks, diskusi, dan pengumpulan feedback. Melalui metode-metode tersebut, pesan utama dari penyuluhan ini dapat dipahami oleh kalangan remaja, yaitu secara aktif melakukan deteksi dini kanker serviks dengan rutin serta dapat menghindarkan dirinya dari pola hidup atau budaya yang memicu terkena kanker serviks.
PELATIHAN MEMBUAT BLOG INTERAKTIF BAGI SISWA PUSAT KEGIATAN BELAJAR MASYARAKAT DENGAN MEMANFAATKAN AKUN GMAIL
Authors: Nawindah Nawindah , Fajarita Lusi
Published: June 2022

ABSTRAK. Pusat Kegiatan Belajar Masyarakat (PKBM) dapat dikatakan maju apabila terjadi partisipasi masyarakat dalam berbagai kegiatan. Keberadaan Universitas Budi Luhur tidak jauh dari PKBM Negeri 27 Petukangan Selatan Jakarta Selatan sekitar 2,2 km. Kondisi PKBM Negeri 27 saat ini belum memiliki laboratorium komputer, sehingga ditemukan beberapa masalah yang dihadapi diantaranya : a.Siswa belum mengetahui bagaimana mendokumentasikan apa yang ada dalam pikiran berupa ilmu pengetahuan, pengalaman, pendapat dengan metode yang sesuai dengan kepribadian masing-masing, b. Bagaimana menarik minat belajar siswa PKBM, c. Bagaimana menghemat biaya publikasi gagasan. Untuk itulah dirasa perlu mengadakan kegiatan pengabdian kepada masyarakat berupa pelatihan membuat blog. Metode yang digunakan: a. Memberikan teori pengenalan dasar tentang internet, b.Metode praktek dalam membuat blog, c. Memberikan soal latihan . Adapun hasil yang didapatkan dari pelatihan tersebut adalah 3 orang peserta mendapatkan nilai baik sekali (A), 5 orang peserta mendapatkan nilai cukup (C) dan 16 orang peserta mendapatkan nilai baik (B).
PENINGKATAN GIZI MASYARAKAT DENGAN MEMANFAATKAN PASCA PANEN TERNAK PUYUH PADA KELOMPOK TANI DI DESA LOA, KECAMATAN PASEH KABUPATEN BANDUNG
Authors: Widjastuti Tuti
Published: June 2022

Desa Loa merupakan desa yang berada di Kecamatan Paseh, Majalaya Kabupaten Bandung yang memiliki potensi di bidang peternakan. Banyak dari penduduknya yang masih belum memanfaatkan potensi yang ada. Salah satu potensi yang harus dikembangkan adalah usaha peternakan puyuh yang menjadi altenatif penghasil daging dan telur yang cukup produktif selain peternakan ayam dan itik. Pasca panen dari beternak puyuh adalah telur, daging dan kotoran. Melihat profil desa seperti di atas, maka kami tertantang untuk memberikan pengetahuan mengenai pemanfaatan ternak puyuh kepada para anggota kelompok tani melalui Kegiatan KKN-PPMD virtual universitas Padjadjaran kepada masyarakat Desa Loa khususnya kepada kelompok peternak. Tujuan melakuka kegiatan ini adalah untuk meningkatkan pengetahuan dan keterampilan dalam budidaya beternak dan pengolahan hasil ternak puyuh. Ternak puyuh mempunyai potensi yang besar untuk dikembangkan karena merupakan penghasil telur dan daging yang cukup baik, tidak memerlukan modal yang terlalu besar serta memungkinkan diusahakan pada lahan yang tidak terlalu luas, sehingga menjadi salah satu dalam meningkatkan gizi masyarakat. Terlihat antusiasme peserta untuk memperoleh pengetahuan dan keterampilan usaha budidaya beternak puyuh cukup tinggi. Wawasan peserta mengenai tatalaksana pemeliharaan dan pengolahan cukup kurang, tetapi animo peternak sangat baik untuk belajar semua pengetahuan tentang budidaya beternak puyuh, sehingga kegiatan ini dapat meningkatkan pengetahuan mengenai manajemen dan keterampilan pengolahan pasca panen puyuh serta semangat untuk usaha beternak puyuh.