bluuebunny/crossref_metadata_2025 huggingface dataset:
LLDPE/TiO2-ZnO Nanocomposite Films induces Transitory Oxidative Stress Response on Human Fibroblast and Blood Cell Lines Models
Authors: Harun Nor Hazliana , Mydin Rabiatul Basria S.M.N. , Sreekantan Srimala , Saharuddin Khairul Arifah , Seeni Azman
Published: July 2023

Healthcare-associated infections (HAIs) are a major safety concern globally that contribute to mortality rates amongst patients especially associated with indwelling or implanted medical devices. The advanced metal-oxide nanocomposites (MNPs) embedded in polymer matrix present an outstanding antibacterial profile, especially for MDR strains owing to reactive oxygen species (ROS) and free radicals’ mode of action. To date, there is still a lack of knowledge on the implication of external reactive species from MNPs-based polymers to humans. This study investigates the bio-interaction of TiO2-ZnO nanocomposite films embedded in linear low-density polyethylene (LLDPE/ TiO2-ZnO) on human fibroblast and blood cell lines model at molecular genes and protein level. The initial analysis of the in vitro bio-interaction responses on fibroblast and blood cell line models showed signs of cell membrane integrity disturbance, which might be due to free radicals’ activities, such as the release of intracellular ROS and Zn ions (Zn2+) during the initial cellular adaptation process on the TiO2–ZnO polymer nanocomposite film. Further findings found that cell–polymer nanocomposite film interaction could possibly trigger transitory oxidative stress response and cellular redox regulation via NF-kβ interactions. However, further comprehensive studies are needed to support this study, especially involving animal models.
Accelerated Variant of an EMD-Based-R Peaks Detection Algorithm Involving FFT-Based Time-Domain Down-Sampling and up-Sampling
Authors: Harkat Amel , Benzid Redha , Athamena Noureddine
Published: July 2023

As most of developed empirical mode decomposition (EMD) based R-peaks detection algorithms consume a considerable time of calculation caused by the large length of the input ECG signal, the design of a new technique that allows the acceleration of such methods becomes necessary. Accordingly, a new variant of an EMD-based strategy for R-peaks localization is presented. The new accelerated variant is constituted of three essential parts. The first step is the length reduction of the input signal by means of the truncation in the Fast Fourier Transform (FFT) domain followed by the application of the inverse FFT guaranteeing a suitable time-domain down-sampling. Consequently, the new input signal of a reduced length preserves all medical information contained initially in the original lengthy signal. The second part is dedicated to identify the QRS complex using EMD-based R-peaks detection. This latter comprises a low-pass filter, Empirical Mode Decomposition (EMD) and the Hilbert transform, Finally, the third phase is the time-domain up-sampling using the FFT, the zero padding and the Inverse Fast Fourier Transform (IFFT) to obtain a resulting processed signal which has the same length as the original signal. Next, as a post-processing step, final R-peaks refined localization is achieved. It is noticeable that the new variant ensures same results, in term of accuracy, as the standard method; however, a significant speed-up ratio of 6.95:1 is reported. Additionally, to more prove the effectiveness of the suggested strategy, it has been applied to accelerate two other efficient algorithms and satisfactory speed up ratios of, 7.20:1 and 4.23:1, respectively have been reached.
Biopolymer Kappa Carrageenan with Ammonium Chloride as Electrolyte for Potential Application in Organic Battery
Authors: Rudati Paula Santi , Dzakiyyah Yumna , Fane Richie , Turnip Maria Artha Febriyanti , Pambudi Muhammad Tegar , Wulandari Priastuti
Published: July 2023

Carrageenan is a generic name for a family of natural, water-soluble, sulphated galactans isolated from red seaweeds and exploited commercially. The biopolymer of kappa carrageenan has been known to be used as electrolyte in electrochemical device since it shows good ionic conductivity characteristic. In this study, we attempt to study the chemical, morphology, and electric properties of biopolymer kappa carrageenan. We developed a free-standing film of kappa carrageenan with addition of ammonium chloride as an electrolyte for an organic battery prototype. We prepared the solution by mixing kappa carrageenan, ammonium chloride and water to form a gel with a particular concentration. Then, the gel was coated on the substrate and cured at 50°C for 4 hours. The final free-standing film product reveals a thickness about 100-200 mm as captured by SEM image in cross-section view. The morphology of kappa carrageenan with or without ammonium chloride clearly shows a non-homogeneous surface that attributed to the nature characteristics of kappa carrageenan immiscible. The addition of ammonium chloride into kappa carrageenan forms a smoother surface that show good mixture of kappa carrageenan. FTIR spectra of the samples show the interaction of ammonium chloride to the host polymer of kappa carrageenan as indicated by the shifted of the O-H peak from 3448 to 3446 cm-1 and from 3288 to 3207 cm-1 while the peak of 2924 cm-1 is disappeared after addition of the ammonium chloride. The implementation of this film in an organic C_Zn battery prototype shows that battery’s voltage reached 2.1 Volt by charging. Then, the battery can be used to emit an LED with 20 µA electrical current for about 1 hour in discharging process.
Anatase/Rutile Phase Control of Titanium Oxide Nanoparticles Synthesized from Potassium Titanium Oxalate by Homogeneous Precipitation and Hydrothermal Methods
Authors: Kajiwara Shohei , Itatani Kiyoshi , Kuwahara Hideki , Yokoi Taishi , Sasaki Tetsuo , Kuroe Haruhiko
Published: July 2023

Preparation conditions of titanium oxide (TiO2) powders were examined by the hydrolysis of titanium potassium oxalate (K2TiO(C2O4)2), through the homogeneous precipitation method (80oC for 24 h) and hydrothermal treatment (160 or 170oC for 1 h). According to the Rietveld analysis, almost a single phase of anatase TiO2 could be obtained by the hydrothermal treatment at 160oC for 1 h, followed by the heating at 900oC for 10 min in air. The molar ratio of anatase to rutile TiO2 was found to be controlled by optimizing the hydrothermal conditions in the solution and the heating conditions in air for the photocatalytic activity.
Screen-Printing of NiO-ScSZ on YSZ Substrate Using Solid-State Reaction and Glycine-Nitrate Process Precursors for Solid Oxide Electrochemical Cells
Authors: Macalisang Christine Mae , Cervera Rinlee Butch M.
Published: July 2023

Solid oxide electrochemical cells (SOCs) consisting of solid oxide fuel cells (SOFCs) and solid oxide electrolysis cells (SOECs) are widely studied for the development of high-efficiency energy generation and storage devices. To investigate the effect of precursor particle size on the microstructural and morphological properties of the electrode, glycine nitrate process and solid-state reaction ball-milling were utilized as synthesis methods for Nickel oxide-scandia stabilized zirconia (NiO-ScSZ) powders. The synthesized powders were then screen-printed on commercial YSZ solid electrolyte substrates. The structure and morphology of the sintered electrodes were investigated. Particle size analysis (PSA) revealed that NiO-ScSZ precursor powders obtained from GNP ball-milled had a smaller average particle size than solid-state reaction ball-milled powders. For the sintered NiO-ScSZ films, cubic structures of both NiO and ScSZ have been observed from the X-ray diffraction (XRD) patterns. A better porous morphology with less agglomeration and better dispersion of NiO and ScSZ phases was revealed by the scanning electron microscopy (SEM) micrographs and elemental mapping for the GNP-ball-milled synthesized powders.
Two Distinct Deleterious Causative Variants in a Family with Multiple Cancer-Affected Patients
Authors: Khorram Erfan , Tabatabaiefar Mohammad A. , Zeinalian Mehrdad
Published: July 2023

Background:

Only 5 to 10% of cancers are hereditary, but they are particularly important since they can be passed down from generation to generation, and family members are at elevated risk. Although screening methods are one of the essential strategies for dealing with hereditary cancers, they do not have high specificity and sensitivity. The emergence of whole-exome sequencing (WES) causes a significant increase in the diagnostic rate of cancer-causing variants in at-risk families.

Materials and Methods:

We performed WES on the proband's DNA sample from an Iranian family with multiple cancer-affected members to identify potential causative variants. Multiple in silico tools were used to evaluate the candidate variants' pathogenicity and their effects on the protein's structure, function, and stability. Moreover, the candidate variants were co-segregated in the family with Sanger sequencing.

Results:

The WES data analysis identified two pathogenic variants (CHEK2: NM_007194.4: c.538C>T, p.Arg180Cys and MLH1: NM_000249.4, c.844G>A, p.Ala282Thr). Sanger sequencing data showed each of the variants was incompletely segregated with phenotype, but both of them explained the patient's phenotype together. Also, the structural analysis demonstrated that due to the variant (c.538C>T), a salt bridge between arginine 180 and glutamic acid 149 was lost. Indeed, several protein stability tools described both variants as destabilizing.

Conclusion:

Herein, we interestingly identify two distinct deleterious causative variants (CHEK2: NM_007194.4: c.538C>T, p.Arg180Cys and MLH1: NM_000249.4, c.844G>A, p.Ala282Thr) in a family with several cancer-affected members. Furthermore, this study's findings established the utility of WES in the genetic diagnostics of cancer.
Alteration in corneal topography asymmetry indices following corneal refractive surgery
Authors: Abdelhalim Tamer I. , Sorour Osama A. , Elkadim Mohamed , Tadros Dina.
Published: July 2023

Purpose

We aimed to follow up corneal refractive asymmetry index changes following refractive surgery for cornea after correction of low-grade myopia and to determine which technique causes marked affection of the indices.

Patients and methods

This prospective study conducted from October 2020 to December 2021 included two groups of patients, the photorefractive keratectomy (PRK) group and the laser in-situ keratomileusis (LASIK) group. Every patient in each group had to follow a schedule of visits after surgery for the next day, 1 week, 1 month, and after 3 months. Patients who failed to follow this schedule were excluded from the study.

Results

The PRK group contained 42 eyes with a mean uncorrected visual acuity that improved significantly, corneal power (K-reading) and pupil center thickness reduced significantly. Surface variance index, central keratoconus index, and height decentration index did not change significantly. Vertical asymmetry index and minimum radius of curvature (Rmin) increased significantly while height asymmetry index decreased significantly. Our LASIK group contained 40 eyes that underwent changes similar to those in the PRK group regarding uncorrected visual acuity, the K-reading, and the pupil center thickness. The surface variance index, vertical asymmetry index, and height asymmetry index, height decentration index and Rmin increased significantly while the central keratoconus index decreased significantly. The keratoconus index reduced significantly in both groups.

Conclusion

The PRK is a more conservative technique than the LASIK technique regarding the affection of corneal asymmetry indices.
Knowledge, attitude and practice of traditional eye medicine use among patients attending a tertiary care hospital
Authors: Sridhar Sriya , Kartha Keerthi M. , Rahul Bhogi , Deeja Santhalayam Sivankunju
Published: July 2023

Purpose

This study is intended to assess Knowledge, Attitude and Practice of traditional eye medicine (TEM) use among the patients attending a tertiary care hospital.

Settings and design

Hospital-Based, Cross-Sectional, Observational Study

Methods and material

Questionnaire-based assessment of knowledge, attitude and practice regarding TEM use.

Results

TEM usage was not gender-dependent. The dependent factors were age, marital status, religious beliefs and socio-economic status. Married and lower socio-economic status participants were more prone to seek TEM. Commonly used TEM were, rose water (31.3%), castor oil (17.9%) and Cucumber (14.9%). 35.8% used TEM following foreign body falling into eye. The commonest symptoms for using TEM were redness (73.1%) and watering (59.7%). 71.64% sought TEM following acquaintances’ advice. 43.28% self-medicated. 87.1% did not have any improvement in symptoms following use of TEM. 58.2% consulted an ophthalmologist within 1 week of no improvement in initial symptoms/following complications from TEM usage. Lack of knowledge was the commonest reason quoted for delay in consultations.

Conclusions

TEM is ineffective, cause ocular complications and can even lead to irreversible blindness. This study gives us an in-depth idea on the need for health education, awareness and reform policies to improve eye health.
Celiac artery thrombosis presenting as acute abdomen
Authors: Sharma M , Natarajan K , Kumar A Mahesh , Paramasivan P
Published: July 2023

Mesenteric vascular thrombosis, typically of the superior mesenteric artery, is a frequent occurrence in patients with hypercoagulable conditions. Isolated involvement of the celiac artery is rare. Patients with celiac artery thrombosis can present with an acute abdomen or occasionally with acid peptic symptoms. A delay in diagnosis is associated with high rates of morbidity and mortality. We present a rare case of splenic infarction with celiac trunk thrombosis in a 54-year-old patient with underlying antiphospholipid (APLA) syndrome who presented with epigastric pain that was mistaken for symptoms of acid reflux.
Решение модифицированного уравнения Камассы-Холма методом обратной задачи рассеяния
Authors: Mao Hui , Yu Qian , Miao Yuanyuan
Published: July 2023

С помощью преобразования взаимности и ассоциативного уравнения изучается обратная задача рассеяния на основе матричной задачи Римана-Гильберта для модифицированного уравнения Камассы-Холма с ненулевыми граничными условиями на бесконечности.
С помощью униформизующей переменной представлены прямая и обратная задачи рассеяния для ассоциированного модифицированного уравнения Камассы-Холма.
С помощью преобразования взаимности и формулы восстановления потенциала этого уравнения построено $N$-солитонное решение для модифицированного уравнения Камассы-Холма с ненулевыми граничными условиями.
В качестве приложения представлены различные решения как светлого, так и темного типа для модифицированного уравнения Камассы-Холма: гладкие солитонные решения, сингулярные солитонные решения, многозначные сингулярные солитонные решения, а также их взаимодействия.
Векторные поля и инварианты полной симметричной системы Тоды
Authors: Sorin Aleksandr Savel'evich , Chernyakov Yury Borisovich , Sharygin Georgii Igor'evich
Published: July 2023

Изучаются геометрические свойства полных симметричных систем Тоды. А именно, описана простая геометрическая конструкция, позволяющая построить коммутативное семейство векторных полей на компактной группе, включающее в себя векторное поле Тоды, т. е. поле, порождающее полную симметричную систему Тоды, связанную с разложением Картана полупростой алгебры Ли. В этой конструкции используются представления полупростой алгебры, и она не зависит от расщепимости пары Картана. Полученный результат тесно связан с семейством инвариантов и полуинвариантов системы Тоды на $SL_n$.
Четырехкомпонентные интегрируемые иерархии гамильтоновых уравнений с парами Лакса ($m+n+2$)-го порядка
Authors: Ma Wen-Xiu
Published: July 2023

Сформулирован класс матричных спектральных задач высокого порядка, и с помощью уравнений нулевой кривизны получены соответствующие интегрируемые иерархии. Для задания гамильтоновых структур полученных иерархий и, таким образом, для исследования их интегрируемости по Лиувиллю используется следовое тождество. Наглядными примерами таких иерархий являются связанные нелинейные уравнения Шредингера и связанные модифицированные уравнения Кортевега-де Фриза с четырьмя компонентами.
Development of Sustainable Ulva Lactuca Genus Algae and Hemp Based Composites for Agrotextiles Application
Authors: KADINKIZ Naz , UZUN Muhammet
Published: July 2023

As the global population grows, there is an increasing demand for food, requiring sustainable farming methods to increase agricultural productivity. Soil covers and mulches used in agriculture are mostly made of synthetic materials derived from petrochemicals, which pose various problems such as soil contamination and long-term insolubility. This study aims to use Ulva Lactuca algae as a sustainable raw material for soil covers, as it contains vitamins and minerals that the soil needs. As seawater acidity increases, the population of this algae is also increasing, creating the opportunity to use it in agriculture. The product is expected to retain moisture and reduce water consumption and high temperatures. In addition, hurds obtained from industrial hemp waste are used due to their high-water retention potential. The study combined Ulva lactuca algae from the Marmara region and hemp strings from Narlı and Vezir seeds to create various composites with different structures. Basic tests were conducted to determine the mechanical and physical properties of the products. The goal is to increase soil organic matter by using these materials as fertilizer after their use as soil covers.
Teknik Dasar Yang Dominan Digunakan Pada Saat Pertandingan Kejuaraan Pencak Silat Piala Ketua Umum IPSI Kabupaten Kediri II-2023
Authors: Moch. Miftachurrohman  , Wasis Himawanto  , Moh. Nurkholis
Published: July 2023

Latar belakang dilakukannya penelitian ini adalah agar para atlit dan pelatih dapat mengembangkan teknik serangan untuk menghasilkan performa yang maksimal. Metode yang digunakan adalah deskriptif dengan pendekatan kuantitatif. Penelitian ini dilakukan pada kejuaraan pencak silat Piala Ketua Umum IPSI Kabupaten Kediri II – 2023 dengan sampel yang digunakan sebanyak G sebanyak 4 orang (berat badan 57 kg - 60 kg). Sebanyak empat atlet diteliti oleh penulis dan penelitian hanya melibatkan empat atlet tersebut.. teknik dasar yang digunakan pada saat pertandingan kejuaraan pencak silat Piala Ketua Umum IPSI Kabupaten Kediri II – 2023 Kategori Tanding Kelas G Putra Remaja adalah pukulan lurus sebanyak 60 dengan presentase 50,54%, tendangan lurus sebanyak 16 dengan presentase 13,44%, tendangan sabit sebanyak 15 dengan pre sentase 12,60%, tendangan T sebanyak 17 dengan presentase 14,28%, guntingan sebanyak 8 kali presentase 6,74%, dan bantingan sebanyak 3 kali dengan presentase 2,52%.tendangan T sebanyak 17 kali (15,74%).
Systemtherapie des Urothelkarzinoms der Harnblase
Authors: Kramer Mario W.
Published: July 2023

Die Systemtherapie des Harnblasenkarzinoms hat durch die Integration immunonkologischer Strategien in die ­Therapiekonzepte bei muskelinvasiven Karzinomen und im metastasierten Stadium deutliche Fortschritte gemacht. Nach dem Versagen von platinbasierter Chemotherapie und Immuntherapie ergeben sich außerdem neue Optionen für die Therapie in späteren Linien. Neben den Inhibitoren des Fibroblasten-Wachstumsfaktor-Rezeptors (FGFR) sind hier vor allem Antikörper-Wirkstoff-Konjugate vielversprechend.
Metastasiertes Nierenzellkarzinom - Erstlinientherapie: Vor- und Nachteile einer ­Kombinationstherapie berücksichtigen
Authors: Hilser Thomas , Bedke Jens , Grünwald Viktor , Darr Christopher
Published: July 2023

Das Nierenzellkarzinom gehört in Deutschland zu den häufigsten malignen Tumoren bei steigender Inzidenz. In der metastasierten Situation haben sich heutzutage kombinierte Therapien mit Immuncheckpoint-Inhibitoren (ICI) als Erstlinientherapie etabliert. Die ICI-Kombinationstherapien sind lebensverlängernde Standardtherapien beim fortgeschrittenen oder metastasierten Nierenzellkarzinom (mRCC), und sie sind der Monotherapie überlegen. Basierend auf den in diesem Beitrag dargestellten Studien sprechen die Autoren in Abhängigkeit des Risikoprofils der Patient:innen Empfehlungen für die Erstlinientherapie aus.
The Role of Management Information Systems in Kerambitan Village Governance with Tri Hita Karana Culture as a Mediation Variable
Authors:   Faculty of Economics and Business, Warmadewa University, Bali, W Mada I Gede Nyoman Carlos , Asteria Putri Putu Yudha ,   Faculty of Economics and Business, Warmadewa University, Bali
Published: July 2023

This study aims to examine the effect of Management Information Systems on Governance. The mediating variable, namely the concept of Hindu culture Tri Hita Karana is included in this study. This research was conducted in one of the agro-tourism villages in Bali, namely Kerambitan Village – Tabanan by taking 128 research samples. The overall model evaluation results are based on the R-Square (R2), Q-Square Predictive Relevance (Q2) and Goodness of Fit (GoF) values, so the model is declared good. The results obtained by the Management Information System have a positive effect on Tri Hita Karana, Tri Hita Karana has a positive effect on corporate governance and Tri Hita Karana mediates the influence of management information systems on corporate governance.
Company Valuation of PT Adaro Energy Indonesia Due to the Coal Price Volatility
Authors:   School of Business and Management, Institute Technology of Bandung, Sinaga Darius Armando , Soekarno Subiakto ,   School of Business and Management, Institute Technology of Bandung
Published: July 2023

This study examines the financial performance and valuation of PT Adaro Energy Indonesia, a major coal mining company in Indonesia, considering declining coal prices. The analysis reveals a downward trend in the forecast coal price index from 2023 to 2030, but the company’s coal production continues to grow due to global demand. Financial ratios indicate a strong performance compared to industry peers. Discounted cash flow analysis shows positive cash flow, assuming coal price growth ceases by 2030 due to zero carbon emission policies. The study concludes that PT Adaro Energy Indonesia is overvalued and suggests strategic measures such as diversification and exploring new business areas to mitigate risks and enhance long-term sustainability.
Challenges to the Teaching of ICT Related Courses in Office Technology and Management Programmes In Colleges of Education
Authors:   Department of Business Education, Ebonyi State University, Abakaliki, Nigeria, A. Igboke Dr. Stephen , Adebanji Olufumilayo ,   Department of Business Education, Ebonyi State University, Abakaliki, Nigeria
Published: July 2023

The study focused on the challenges to the teaching of ICT-related courses in OTM programmes of Colleges of Education in Katsina and Kano States. Two research questions and two null hypotheses guided the study. The design of the study was a survey design. The population of the study comprised one hundred and seventy-seven (177) lecturers in the Department of Business Education in the Colleges of Education in Katsina and Kano States. There was no sampling. The entire population was studied. A structured questionnaire duly validated and with reliability coefficient of 0.95 was used for data collection. One hundred and seventy-seven copies of the questionnaire were administered on the respondents. All the copies were accurately completed and returned. Mean and standard deviation were used to answer the research questions while t-test was used to test the hypotheses at 0.05 confidence level. The results of the study showed that the challenges to teaching of ICT related courses in Office Technology and Management (OTM) programmes in colleges of education are teaching facilities and human resources related. It was also found that there is a significant difference between the mean responses of male and female lecturers on teaching facilities related challenges to the teaching of ICT-related courses in OTM programmes in Colleges of Education. In addition, it was found that there is a significant difference in the mean response of lecturers on human resources-related challenges to the teaching of ICT-related courses in OTM programmes in Colleges of Education based on ownership. The implication is that OTM education graduates may not be relevant in this era of ICT if these challenges are not well tackled by the management of colleges of education. It was recommended, among others, that management in colleges of Education should provide adequate ICT teaching facilities and adequate human resources for effective implementation of OTM programmes. Government should provide adequate funding to enable effective provision of teaching facilities and appropriate mix of the quality and quantity of human resources needed for the effective implementation of ICT related programmes in OTM in the colleges of education.
Relationship between Arm Muscle Strength, Lemb Muscle Strength, and Eyes-Feet Coordination with Basic Movement Ability of Elementary School Students
Authors:   Sports Science Study Program, Faculty of Sports,Universitas Sebelas Maret Ir. Sutami Street Number 36, Kentingan, Kec. Jebres, Surakarta City, Central Java 57126, Indonesia, Karismadarma Dinasti Rahma , Sugiyanto Sugiyanto ,   Sports Science Study Program, Faculty of Sports,Universitas Sebelas Maret Ir. Sutami Street Number 36, Kentingan, Kec. Jebres, Surakarta City, Central Java 57126, Indonesia, Ekawati Febriani Fajar ,   Sports Science Study Program, Faculty of Sports,Universitas Sebelas Maret Ir. Sutami Street Number 36, Kentingan, Kec. Jebres, Surakarta City, Central Java 57126, Indonesia, Riyadi Slamet ,   Sports Science Study Program, Faculty of Sports,Universitas Sebelas Maret Ir. Sutami Street Number 36, Kentingan, Kec. Jebres, Surakarta City, Central Java 57126, Indonesia
Published: July 2023

Purpose: The purpose of this study was to examine relationship between arm muscle strength, lemb muscle strength, and eyes- feet coordination with basic movement ability of elementary school students. Materials and Methods: The use of quantitative methods to examine certain populations or samples, generally sampling techniques are random or random, requires research instruments for data collection. The study was conducted in that place because researchers wanted to test the basic movement skills of upper class students of Madrasah Ibtidaiyah Negeri Kota Cirebon. The total of the 6 classes is 62 male students. Test the hypothesis of the relationship level of arm muscle strength, leg muscle strength, and eye-foot coordination together with basic motion ability using multiple correlation coefficients. Results: Based on the analysis, a value coefficient of 20.583 > (2.79) was obtained at a significance level of 5% and = 0.929 > = 0.279, thus it is interpreted that there is a significant relationship between arm muscle strength, leg muscle strength and eye-foot coordination with the basic movement ability of MIN Cirebon City male students. This relationship means that there is a relationship between these variables with basic motion ability. When performing each daily activity the strength of arm muscles, leg muscles, and eye-foot coordination contributes to the results of movement. Conclusions: Based on the research results, it can be concluded that there is the contribution was arm muscle strength of 13.39%, leg muscle strength of 15.51%, and eye-foot coordination of 26.38%, and the remaining 44.7% was influenced by other factors that were not studied in this study.
Single Versus Double Layer Uterine Closure Technique According to Development of Uterine Niche: A Literature Review
Authors:   Margono Soekarjo County Hospital – Faculty of Medicine University of Jenderal Soedirman, Indonesia, Alhamdi Mochammad Haikal , Fawzy Ahmad ,   Margono Soekarjo County Hospital – Faculty of Medicine University of Jenderal Soedirman, Indonesia, Margono Rudi ,   Margono Soekarjo County Hospital – Faculty of Medicine University of Jenderal Soedirman, Indonesia, Kuncorojati R. Alif ,   Margono Soekarjo County Hospital – Faculty of Medicine University of Jenderal Soedirman, Indonesia
Published: July 2023

Prevalence of cesarean deliveries increases globally. The prevalence of cesarean births increased from 5% in 1970 to 31.9% in 2016. There are short term and long-term complications of cesarean delivery including uterine niche. After a cesarean, the uterus is closed using a variety of methods, such as single- and double-layer closures with/without locking. This study compared single-layer and double-layer uterine closure with regard to the outcomes and complications. This review was synthesized and obtained from various online databases. Scientific articles were selected based on the inclusion criteria. The result showed that cesarean deliveries is a hysterotomy and an open abdominal incision (laparotomy) to deliver the fetus. An iatrogenic pouch-like defect known as a uterine niche result from improper tissue repair at the site of a prior cesarean scar. Up to 70% of women who have had a prior cesarean section experience uterine niche, of which 30% have symptoms. Compared to a single full-thickness closure, a single-layer, decidua sparing closure approach is more likely to result in an incomplete closure. No differences were discovered between the single- and double-layer closure techniques with locked first layers, but double-layer closures without locking resulted in thicker residual myometrium thickness when compared with locked single-layer closures. It is also possible that the locked suture can strangulate the scar tissue leading to poorer healing. Current evidence shows that no significant difference between single-layer and double-layer uterine closure techniques following in terms of uterine niche development.
Mesenchymal Stem Cells (MSCs) Therapy for Pressure Ulcers: A Literature Review
Authors:   Margono Soekarjo County Hospital – Faculty of Medicine University of Jenderal Soedirman, Indonesia, Margono Rudi , Fawzy Ahmad ,   Margono Soekarjo County Hospital – Faculty of Medicine University of Jenderal Soedirman, Indonesia, Kuncorojati R. Alif ,   Margono Soekarjo County Hospital – Faculty of Medicine University of Jenderal Soedirman, Indonesia, Alhamdi Mochammad Haikal ,   Margono Soekarjo County Hospital – Faculty of Medicine University of Jenderal Soedirman, Indonesia
Published: July 2023

Pressure ulcers or injuries, arise from ischemic damage to soft tissues induced by unrelieved pressure over a bony prominence. They are usually difficult to treat with standard medical therapy and often they recur. Promising alternative methods for treatment are now developing in the search for better treatment choices. Within the field of regenerative medicine, ongoing research on advanced therapies seeks to treat pressure ulcers with mesenchymal stem cells (MSCs). This review was synthesized and obtained from various online databases. Scientific articles were selected based on the inclusion criteria. MSCs have anti-inflammatory capabilities, they are very helpful for treating chronic wounds such as pressure ulcers because they can restart healing infected wounds by moving the wound through a chronic inflammatory state and into the subsequent stage of healing. The research indicates that MSCs produce soluble compounds that promote the proliferative and migratory behavior of the dominant cell types in the wound. MSCs promote wound closure with promoting angiogenesis, granulation tissue production, and faster epithelialization. Additionally, it was discovered that the cells create bioactive chemicals that appear to accelerate the regeneration process. These findings show that MSC therapy affects all stages of wound healing, including inflammation, epithelialization, development of granulation tissue, and tissue remodeling. Although there are many medications to treat pressure ulcers, there are surprisingly new therapies that take use of MSCs' positive benefits and crucial for wounds that are difficult to heal.
The Juridical Analysis of Corporate Crimes Accountability in the Indonesian Penal System
Authors:   Master of Law, Faculty of Law, Diponegoro University, Indonesia, Winjaya Dadang Kurniawan , Pujiyono Pujiyono ,   Master of Law, Faculty of Law, Diponegoro University, Indonesia
Published: July 2023

Evil grows as society progresses, not only to the types and methods of evil, but also to the subject or perpetrator themselves. Corporate acceptance asa subject of criminal action, which leads to criminal law enforcement problems in corporate criminal liability. Whereas law enforcement doesn't recognize corporations as the subject of law, allowing people to exploit their legal loopholes. As for the rules governing corporate accountability that exist up until now are considered less effective and efficient. The clear corporate policy is still at the stage of criminal design that has been fully regulated and firm as the subject of criminal law and is accountable in criminal law and receives absolute criminal accountability and replacement crimes, even with the exception of solving the difficulties of proving an element of wrongdoing committed by a corporation. Research methods used are normative law research methods with law enforcement approaches, comparisons and concept analysis of the law.
Juridical Implications of the Regulation on Specific Time Work Agreements for Termination of Employment and Overtime Pay in Indonesia
Authors:   Master of Law Program, Diponegoro University, Zakiyya Ferian Luthfi , Purwanti Ani ,   Master of Law Program, Diponegoro University
Published: July 2023

Government Regulation No. 35 of 2021 concerning work agreements for a certain time, outsourcing, work time and rest time, and termination of employment, hereinafter referred to as the Regulation concerning work agreements for a certain time, raises various fundamental questions which is also the problem raised in this research. The first problem is what are the implications of the Regulation regarding work agreements for a certain time for overtime pay in Indonesia? and the second problem, namely what are the implications of the Regulation regarding work agreements for a certain time on Termination of Employment? These problems were analyzed using normative juridical research methods. Based on the results of the study it was concluded that overtime pay is a right owned by workers/laborers who are given by employers/employers as a consequence of work performed outside working hours. Overtime pay is also an obligation owned by employers/employers to be given to workers/laborers for their work. Wages begin when work begins and end when employment is terminated. Whereas employers/employers who do not fulfill their obligations to pay overtime wages to workers/laborers will be subject to criminal sanctions.
Effect of Green Accounting, Quality Management on Financial Performance, and Green Innovation as Moderation Variables
Authors:   Mercu Buana University, Jakarta Indonesia, Choiriah Siti , Lysandra Shanty ,   Pancasila University, Jakarta Indonesia
Published: July 2023

This study empirically examines whether green innovation moderates the relationship between Green Accounting, Quality Management, and Financial Performance. This research is a causal descriptive quantitative research on traditional banking companies listed on the Indonesia Stock Exchange (IDX). This survey data is secondary data from the 2018-2021 Financial and Sustainability Reports of banking companies listed on the Indonesia Stock Exchange. It consists of three independent variables. Green accounting, Quality Management, and Green Innovation. The dependent variable is Financial Performance. The results show that Green Accounting affects Financial Performance, but Quality Management does not, whereas Green innovation moderates the relationship between Green Accounting and Financial Performance and between Quality Management and Financial Performance.
Implementasi Data Mining Menggunakan Algoritma Fp-Growth Untuk Menganalisa Transaksi Penjualan Ekspor Online
Authors: Hafizh Muhammad , Novita Triana , Guswandi Dodi , Syahputra Hadi , Mayola Liga
Published: July 2023

In today's online technology, we have to learn various things so that we can adjust to social behavior, for example, buying and selling activities that cover all walks of life, now everyone doesn't hesitate to shop online. The online market is growing fast, especially in Indonesia. Anyone can sell and buy goods easily through online stores, so that people's purchasing power and sales increase due to the proliferation of online stores, XYZ stores are still beginners in terms of sales strategies so they try all efforts without careful preparation, one of the ways to do this is to expand its market coverage even to export goods abroad. the process of exporting goods in the current era is not a difficult thing to do, but it requires knowledge and preparation of a good strategy. from existing sales data can be analyzed to determine the right strategy in marketing goods. Data Mining is a science that helps analyze large amounts of data with the aim of gaining new knowledge that can be utilized. In Data Mining Analysis there is the FP-Growth algorithm which is a data mining technique for finding association rules from lots of data. This is known as the Association rule, where the rule will be determined from the minimum support and confidence results. the rules that are formed produce 10 rules out of 51 existing data, these rules help determine the export sales strategy at the XYZ store.
The Role of Information Technology in Improving Human Resources Career Development
Authors: Prastyaningtyas Efa Wahyu , Almaududi Ausat Abu Muna , Muhamad Lili Fadli , Wanof M. Indre , Suherlan Suherlan
Published: July 2023

The ubiquity of information technology in contemporary society has rendered it an indispensable component across a wide. The significance of information technology in the advancement of human resource careers is progressively gaining momentum in the current era of globalisation and rapid technological development. The impact of information technology on the business environment has resulted in significant changes in the management of human resources within organisations. The objective of this investigation is to examine the influence of information technology on the progression of HR careers, investigate the related obstacles and prospects, and furnish pragmatic recommendations for enterprises to proficiently adopt and execute information technology in HR career development. The central focus of this inquiry is predominantly qualitative in character. The methodology of acquiring data entails a rigorous approach of observing and documenting data, which is then subjected to analytical techniques such as data reduction, visualisation, and inference to extract significant findings. The research findings indicate that the utilisation of information technology plays a crucial role in enhancing the professional growth of human resources. The field of information technology facilitates convenient retrieval of information, affords avenues for remote education, enables networking among professionals, and offers tools for enhancing productivity. This facilitates the human resources department to augment their skill set, broaden their knowledge base, establish professional connections, and leverage existing career prospects.
Web Store Teh Krisan (erpekrisan) Rachmat Purnama Farm
Authors: Renanti Medhanita Dewi , Ristianingrum Anita , Lidya Leni
Published: July 2023

The Rachmat Purnama Farm Company, a producer of chrysanthemum flowers located in Cianjur Regency, has made efforts to process chrysanthemum flowers into chrysanthemum tea. However, the marketing remains limited, as sales are conducted directly. Consequently, the company recognizes the need for an online web store to enhance its marketing reach. The purpose of this system is to provide customers with information about chrysanthemum tea and facilitate convenient purchase transactions. The waterfall model is used as the software development method, which covers requirements analysis, system design, program code development, program testing, and program implementation and maintenance. The features of the online web store include account management, customer management, product categorization, product listings, attributes, sales, payments, shipping, and transaction reports. The implementation has positively impacted the company’s sales of chrysanthemum tea products, as shown by the increasing number of online purchases. Moreover, the marketing area coverage has expanded to Jakarta and Kalimantan.
Value Engineering Techniques and its Application in Construction Projects
Authors:   Civil Engineering Department, Al Gubba, University of Derna, Libya, Younis Elfargani Mabrouka Shahat
Published: July 2023

Value Engineering (VE) is an efficient management technology that can significantly contribute to value rise and decrease in building projects. In addition to that EV is an accepted way of recognizing and removing excessive product construction, inspection, manufacture and design, operation, repairs. The technique comprises three main stages. The first step of the study on VE is designed to schedule and organize the study of significance. Value Engineering routinely employs well-known techniques that classify the functions of the innovative product or service and thus operate at the lowest average cost of performance. Value engineering relies on the lowest marginal feature efficiency. It enables waste, time, and unnecessary expenses to be eliminated or minimized that increases customer loyalty. The second step consists of several phases: knowledge phase, research purposes phase, innovative phase, assessment phase, and initial phase. The principal components of value engineering study are value analysis. Value analysis. The two steps and actions function sequentially. This series of approaches to the VE research goals will lead to a logical and organized process flow. The third step is postal analysis. It seeks to ensure that the acceptance criteria are applied to change the research of significance in the course of study operations. The second process consists of five phases: information phase, purpose analysis phase, creative phase, evaluation phase, and introduction phase. Value analysis is the main component of Value Engineering Research. Sequentially both stages and measures work. The rational and structured process flow is anticipated to help with this sequence of the approach to reach the VE research goals. The postal study is the third phase. It is intended to ensure the execution of the agreed guidelines to modify the important study during study operations. In the study, the values engineering principles are applied and value engineering practices in this project are defined by the study of the constructor project.
Seksio Seserea dan Tubektomi dengan Regional Anesthesia Subarachnoidal Block pada Multigravida Preterm dengan Preeklamsia Berat, Sindrom HELLP, dan Obesitas
Authors: Supraptomo RTH
Published: July 2023

Preeklamsia berat (PEB) serta sindrom hemolysis, elevated liver enzymes, and low platelets (HELLP) merupakan komplikasi yang bersifat fatal pada ibu hamil, dimana kondisi ini juga dapat mengancam kondisi janin. Seksio sesarea merupakan tindakan yang dipilih pada pasien dengan kondisi tersebut. Manajemen anestesi yang baik dapat menurunkan risiko komplikasi pasca persalinan pada pasien. Laporan kasus ini bertujuan untuk membahas mengenai manajemen anestesi pada pasien multigravida preterm dengan PEB, sindrom HELLP, dan obesitas. Seorang wanita, 48 tahun G4P2A1, usia kehamilan preterm, dengan PEB, sindrom HELLP, dan obesitas kelas II, status fisik ASA II direncanakan untuk dilakukan sectio caesarea transperitoneal profunda (SCTP) dan metode operasi wanita (MOW). Teknik regional anesthesia subarachnoidal block (RASAB) dengan menggunakan kombinasi levobupivakain dan fentanil diberikan pada pasien. Manajemen pasca operasi tidak didapatkan adanya komplikasi pada pasien. Teknik anestesi RASAB aman diberikan kepada pasien hamil dengan komplikasi multipel dimana teknik ini juga mengurangi rasa nyeri pasca pembedahan dengan baik
A Review on Markhor (Capra falconeri falconeri Wagner 1839) population trends (2016-2019) and community-based conservation in Toshi Shasha, Gehrait Goleen, Kaigah Kohistan Conservancies and Chitral Gol National Park, Khyber Pakhtunkhwa, Pakistan
Authors: Kakakhel Syed Fazal Baqi
Published: July 2023

Purpose: Recognizing the dynamics of ungulate populations is vital because of their economic and ecological significance. The dry temperate ecosystem of Hindu Kush is one of the most remarkable and significant mountain ranges, which supports near threatened markhor population in districts Chitral and Kohistan of Pakistan. However, the current population trends and community-based management of markhor are data lacking or unrevealed, requiring a crucial need for research to examine. The central goal of this study is to review population trends (2016-2019) of markhor and community-based conservation in Toshi Shasha, Gehrait Goleen conservancies, Chitral Gol National Park in district Chitral and Kaigah conservancy in district Kohistan using well developed questionnaire.Methodology: Review of existing record of Khyber Pakhtunkhwa Wildlife Department Pakistan through a well-developed questionnaireFindings: The finding revealed that over a period of four years population of markhor enlarged to 5658 individuals, fawn population to 2185, female population to 1589, young population to 1491 and the trophy size male increased to 850. Community based conservation resulted 15 markhor trophy hunts in Toshi Shasha, Gehrait Goleen and Kaigah conservancies with gross income of USD 5770400 except Chitral Gol National Park where trophy hunting is not allowed under Khyber Pakhtunkhwa Wildlife and Biodiversity Act 2015.Unique contribution to the theory, practice and policy:The author recommended that, As the government has fixed Markhor trophy hunting quota of hunting four animals per year in Khyber Pakhtunkhwa province of Pakistan. This quota of Markhor trophy hunting should not be fixed but should be based on population of Markhor with reference to trophy size male. The present quota of four Markhor trophy hunt need to be increase from 4 animals per year to 1% leading to 2% of the population of markhor. As the population of Markhor in Chitral Gol National Park Khyber Pakhtunkhwa Pakistan has been increased to 2926 individuals and have enlarged to buffer zone of the National Park. At least 1% of Markhor trophy hunts in buffer zone is recommended to support local community for their livelihood improvement and encouragement of the conservation. The community organizations should be strengthened in terms of establishing their offices, field equipment and mobility beside protection.