bluuebunny/crossref_metadata_2025 huggingface dataset:
Financial fragility and demographic factors predict pet owners’ perceptions of access to veterinary care in the United States
Authors: King Erin , Mueller Megan K. , Dowling-Guyer Seana , McCobb Emily
Published: April 2022

OBJECTIVE

Access to veterinary care is critical for pet, human, and community health. However, inequities in how easily pet owners can access veterinary care may exacerbate health disparities in vulnerable populations. This research analyzed pet owners’ perceptions of access to veterinary care in order to understand how demographic characteristics and financial fragility predict perceived access to veterinary services.

SAMPLE

This study utilized survey data (n = 750) from a larger cross-sectional survey of adults in the US conducted by the Tufts University Equity Research Group.

PROCEDURES

Survey data were collected in May and June of 2020 from a nationally representative group of pet owners via an online panel. Descriptive statistics, ANOVAs, and a sequential linear regression model were conducted in order to predict perceived access to veterinary care.

RESULTS

Results of a sequential linear regression model indicated that race or ethnicity, education, and financial fragility significantly predicted perceived ease of access to veterinary care (F[7,617] = 19.80; P < .001). Additionally, financial fragility was prevalent among most pet owners of almost all income brackets, highlighting the need for more research into the cost burden of veterinary care.

CLINICAL RELEVANCE

Future studies should focus on diverse sampling strategies that capture the experiences of minority pet owners in order to further understand issues of access in veterinary medicine.
CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELLS THERAPY UNTUK PENYAKIT AUTOIMUN
Authors: Iqbal Roihan Mohamad , Ardanari Anindya Intan , Amany Muthia Fahiratunnisa , Oktarina Dyah Ayu Mira
Published: April 2022

Introduction: Pemphigus vulgaris (PV) is a rare and potentially life-threatening chronic bullous autoimmune disease caused by the presence of desmoglein 3 adhesion protein autoantibodies. The most commonly used PV treatment remains immunosuppressants which have adverse effects such as increased immune responses and relapse later on. Therefore, innovative therapeutic strategy that more targeted and can prevent relapse in the long term are needed for autoimmune diseases treatment. eview current trends of CAR T-cell applications in PV. The objectives of this study is to review current trends of CAR T-cell applications in PV.Discussion: The presence of autoantibodies against desmoglein 3 (?Dsg3) is commonly found in patients with PV. ?Dsg3 is localized to the mucous membrane and mucocutaneous. Autoantibodies appear due to overactivation of CD4+ Th2 cells. CAR T-cell is the result of the engineering of vector-assisted T cells that carry the chimera receptor according to what is targeted. This treatment with CAR T-cell is increasingly promising after FDA approval of two drugs for haematological cancer. Researchers are interested in developing CAR T-cell as a treatment for autoimmune disease. In vitro results from CAAR T-cell (which is modification of CAR T-cell) showed specific cytotoxicity activity against ?Dsg3 BCR. The results of the study in vivo discussed the potential for specific elimination of B cells Dsg3 based on serum and succeeded in maintaining epidermal integrity in mice.Conclusion: CAR T-cell shows the potential to be applied as a choice for PV therapy in the future. Nevertheless, further development of the application of CAR T-cell is needed for PV therapy so that specific treatment options can be obtained with minimal adverse effects for patients
Prevalence and Hemodynamic Outcome of Dengue Shock Syndrome in Children Attending the Department of Pediatrics, Dr. Soetomo General Hospital
Authors: Seipalla Fenska , Dharmawati Ira , Wiyasihati Sundari Indah
Published: April 2022

Abstract

The prevalence of Dengue infection has increased markedly worldwide. Dengue shock syndrome (DSS) is a severe manifestation of dengue virus infection. Higher mortality of DSS was found in children. This study’s aim was to portray prevalence and hemodynamic outcome in children attending the department of pediatric in Dr. Soetomo General Hospital. A Descriptive Retrospective study of children aged <15 years old with DSS was performed and evaluated from 2013-2016. The samples were divided into 5 groups, aged <1 years old, 1-2 years old, 3-5 years old 6-11 years old and 12-15 years old. Data were taken secondarily and calculated with Microsoft Excel 2010. The most common findings were prevalence of DSS in 6-11 years old group and mortality rate in <1 years old group.  This can be seen as in the hemodynamic outcome; the average HR was higher in aged group 1-2 years old while RR was higher in group under 1-year-old. Meanwhile, the average blood pressure, PP, and MAP were lower in children under 2 years old. The hemodynamic outcome varies on each group based on age. Incidence of DSS remained high in older children but mortality rates were high in younger children.
EFEK PEMBERIAN EKSTRAK BIJI PEPAYA (Carica papaya Linn.) TERHADAP GAMBARAN HISTOPATOLOGI TESTIS PADA MENCIT (Mus musculus) JANTAN
Authors: Widyanjaya Anak Agung Gede Fandhiananta , Sista Satyarsa Agung Bagus , Dharmadi Ni Luh Gede Ayu Candranita , Sari Maura Marda Mayang , Laveda Xena , Satriyasa Bagus Komang
Published: April 2022

Pepaya (Carica papaya L.) merupakan tanaman yang hampir semua bagiannya dapat digunakan untuk keperluan manusia. Salah satunya adalah biji pepaya yang telah diuji memiliki efek antifertilitas. Kriteria kontrasepsi yang baik yakni mudah digunakan, efektif, efisien, tidak ada efek samping dan bersifat refersibel yang dapat digunakan dalam jangka waktu panjang. Penelitian ini dilakukan untuk mengetahui efek ekstrak biji pepaya terhadap gambaran histologi testis. Penelitian eksperimental ini menggunakan sebanyak dua puluh tujuh ekor mencit jantan fertil. Kelompok kontrol (P0) diberikan akuabides per oral sebanyak 0,5 ml selama 36 hari. Kelompok perlakuan 1 (P1) diberikan ekstrak biji pepaya muda per oral dengan dosis 20 mg/mencit/hari sebanyak 0,5 ml selama 36 hari. Kelompok perlakuan 2 (P2) diberikan ekstrak biji pepaya muda per oral dengan dosis 50 mg/mencit/hari sebanyak 0,5 ml selama 36 hari. Berdasarkan hasil penelitian dapat disimpulkan bahwa pemberian ekstrak biji pepaya pada dosis 20 mg dan 50 mg selama 36 hari pada mencit jantan berpengaruh terhadap kerusakan struktur histologi testis. Maka dari itu, biji pepaya dapat menyebabkan infertilitas sehingga dapat dikembangan sebagai bahan kontrasepsi alami pada pria.
POTENSI LUMBROKINASE DENGAN CARRIER N,N,N-TRIMETIL KITOSAN KLORIDA (TMC) MENGGUNAKAN LIGAND C-RGD SEBAGAI AGEN FIBRINOLITIK DAN ANTI-PLATELET TERBARUKAN
Authors: Firsty Naufal Nandita , Furqan Muhammad , Aritonang Ilman Arif
Published: April 2022

Introduction: Venous thrombosis is the third most cardiovascular disease in the world. Administration of fibrinolytic agents such as streptokinase is the chosen treatment of the disease. However, the disadvantages are short half-time, unspecific to fibrin, poor targeting, expensive price, and tend to cause bleeding. Therefore another fibrinolytic agent is needed to cope with some of the deficiencies and side effects of current fibrinolytic agents. This literature review aims to explain the potential of lumbrokinase with TMC carrier and c-RGDligand as a renewable fibrinolytic and antiplatelet agent. The method used in this literature review is a literature study using the last 10 years of journal gained from some search engines such as ScienceDirect, PubMed, Google Scholar, and ClinicalKey.

Discussion: Lumbrokinase is an enzyme from the extraction of the earthworm’s digestive tract which consists of several serine protease isoenzymes. As a fibrinolytic agent, lumbrokinase can hydrolyze both fibrin or fibrinogen and also activate plasminogen into plasmin. Besides, lumbrokinase is known as has an antiplatelet effect as aspirin has. The use of TMC as the carrier can increase the bioavailability of lumbrokinase. Meanwhile, the addition of c-RGD ligand can increase the specificity preventing fibrinogen to bind the GPIIb/IIIa receptor thereby inhibiting thrombus formation.

Conclusion: From various in vitro and in vivo studies, it was concluded lumbrokinase with carrier TMC and c-RGD ligand can accelerate thrombolysis, and reduce the risk of bleeding so that it’s potentially a renewable fibrinolytic and antiplatelet agent. However, further research is needed regarding therapeutic doses, side effects, and toxicity studies.
Penggunaan Beberapa Model Peramalan (Forecasting) pada Produksi Gula Kristal Putih di PT. Perkebunan Nusantara X
Authors: Damanik Immanuel , Gunadnya Ida Bagus Putu , Aviantara I Gusti Ngurah Apriadi
Published: April 2022

ABSTRAK

Peramalan adalah proses memperkirakan atau  memprediksi apa yang akan terjadi di masa yang akan datang berdasarkan data masa lalu dan data saat ini, yang paling umum dengan analisis tren. Contoh peramalan yang sederhana adalah peramalan nilai suatu variabel pada beberapa waktu yang akan datang. Tujuan dari penelitian ini adalah (1) untuk mengetahui pola historis data produksi gula, (2) untuk mengetahui model peramalan yang digunakan dan menentukan model peramalan terbaik dan validitas model, dan (3) melakukan peramalan produksi gula beberapa bulan kedepan dengan menggunakan model peramalan yang valid. Metode penelitian ini menggunakan data sekunder dari PT. Perkebunan Nusantara X dan proses pengolahan data menggunakan Microsoft Excel. Berdasarkan hasil dari analisis, exponential smoothing menggunakan ? = 0.8 merupakan model peramalan terbaik. Bila dibandingkan model peramalan moving average 2 periode dan double exponential smoothing dengan ? = 0.8. Uji keakuratan dari exponential smoothing ? = 0.8 menunjukkan nilai MAD = 1.096, MSE = 2.818.871, dan MAPE = 34%. Pada uji validitas model peramalan, model ini memiliki nilai MAD = 1,025, MSE = 2,113,927, MAPE = 22%. Hasil peramalan produksi untuk 6 periode kedepan adalah R1 = 5,106, R2 = 5,047, R3 = 5,035, R4 = 5,032, R5 = 5,032, R6 = 5,032

 ABSTRACT

Forecasting is the process of making a future prediction based on the present and past data using trend analysis. The purpose of this study was (1) to know the historical pattern of refined sugar production, (2) to know what are the forecasting models that be used for prediction, (3) to get the best forecasting model by using an accuracy test. This study uses secondary data from PT Perkebunan Nusantara X and processing data by using Microsoft Excel. Based on analysis results exponential smoothing by using ? = 0.8 is the best model. As comparison by using a moving average with 2 period and double exponential smoothing with ? = 0.6. The accuracy test of exponential smoothing ? = 0.8 showing with value MAD = 2, MSE = 9, and MAPE = 36%. On validity test of forecasting models, exponential smoothing had showing value MAD = 1,025, MSE = 2,113,927, MAPE = 22%. Results of forecasting production with 6 period on the future is R1 = 5,106, R2 = 5,047, R3 = 5,035, R4 = 5,032, R5 = 5,032, R6 = 5,032.
Pengaruh Ketebalan Plastik Polietilen Densitas Rendah sebagai Bahan Pengemas terhadap Mutu Peterseli (Petroselinum crispum L.) selama Penyimpanan Suhu Dingin
Authors: Tampubolon Bob Evan , Pratiwi Ida Ayu Rina Pratiwi , Gunadnya Ida Bagus Putu
Published: April 2022

ABSTRAK

Riset ini bertujuan untuk mengetahui pengaruh ketebalan plastik polietilena berdensitas rendah sebagai material pengemas terhadap kualitas Peterseli (Petroselinum crispum L.) selama penyimpanan dingin. Rancangan yang digunakan pada penelitian ini adalah metode Rancangan Acak Lengkap (RAL) menggunakan satu faktor perlakuan yaitu perlakuan ukuran ketebalan plastik polietilena berdensitas rendah (LDPE) dengan ukuran 0.02mm; 0.03mm; 0.04mm; 0.05mm; dan ketebalan 0.06mm. Penelitian ini diulangi sebanyak 3 kali ulangan sehingga didapatkan 18-unit hasil percobaan. Adapun parameter yang diamati meliputi; susut bobot, karakteristik, uji warna, tingkat kerusakan dan laju respirasi. Hasil dari penelitian ini menunjukkan bahwa ketebalan plastik densitas rendah (LDPE) berpengaruh sangat nyata terhadap susut bobot, karakteristik tingkat kerusakan dan laju respirasi dari peterseli. Perlakuan terbaik didapatkan dari penggunaan plastik LDEP dengan ketebalan 0.05mm dengan susut bobot 13.93%, warna 18.96, laju respirasi 43.81 mg CO2/kg/jam, nilai uji skoring karakteristik 3.73 dan tingkat kerusakan 3.87. Plastik LDPE dengan ketebalan 0,05mm dapat mempertahankan mutu peterseli lebih baik dibandingkan dengan ketebalan lainnya selama karakteristik 12 hari pada suhu dingin.

ABSTRACT

This research was aimed to determine the effect of Low-density polyethylene as packaging material for the quality of parsley (Petroselinum crispum L.) during cold room. Additionally, this study was to determine the thickness of the low-density polyethylene plastic which can retain the grade of parsley for a longer time. The design experiment used in this study was a Completely Randomized Design (CRD) method using one treatment factor, namely the treatment of low-density polyethylene plastic thickness (LDPE) with a thickness of 0.02 mm; 0.03 mm; 0.04 mm; 0.05 mm; and a thickness of 0.06 mm. This research was replicated 3 times in order to obtain 18 units of experimental results. The parameters observed include: weight loss, characteristics, color test, damage rate, and respiration rate. The results of this research signified that the thickness of low-density plastic (LDPE) gave a very significant effect on characteristics, color test, damage rate, respiration rate, and weight loss. The best handling was obtained by use of LDPE plastic with a thickness of 0.05 mm with a weight loss of 13.88%, the color of 13.93, 43.81 mg CO2/kg/hour for respiration rate, characteristic scoring test value of 3.73, and 3.87 for damage level. Low-density polyethylene plastic with a thickness of 0.05 mm can retain the quality of parsley better than other thicknesses during shelf life of 12 days at 8°C ± 2°C.
Eksplorasi Pengetahuan Guru Inklusi Mengenai Pendidikan Seksual di Masa Pubertas Remaja Putri dengan Disabilitas Intelektual Ringan
Authors: Nadirah Agfa Aghnia , Novianti Langgersari Elsari , Agustiani Hendriati
Published: April 2022

Sexual education at puberty is needed for young women with mild intellectual disabilities (ID) to help with puberty. Through sexual education, young women can have a better understanding of the changes that occur in their bodies and the right behavior to show in the social environment. This study aims to determine the knowledge of inclusive teachers about sexual education at puberty for young women with mild intellectual disabilities. This research was conducted using the principles of qualitative research. Data obtained based on interviews using telephone media to 4 inclusive school teachers in Bandung. Data were analyzed using thematic analysis techniques. The results show that knowledge about the characteristics of ID is still not mastered by all teachers. Knowledge about how to teach students with mild ID in the academic settings and the characteristics of puberty is owned by the four teachers based on their experience. However, all teachers do not yet have complete knowledge about the scope of sexual education material that needs to be provided as well as how to provide effective sexual education for young women with mild ID. Further research can be carried out to develop an intervention program design to improve the knowledge and skils of inclusive teachers to provide sexual education at puberty
Peran dukungan pasangan dan keyakinan diri mengelola konflik kerja-keluarga terhadap konflik kerja-keluarga selama work fromhome pada dosen wanita yang sudah menikah
Authors: Andhini Luh Putu Ratih , Utami Ni Made Sintya Noviana , Dewi Anak Agung Dyah Pramudya , Shantiyani I Gusti Ayu Yurika Wahyuning
Published: April 2022

Work-family conflict have been strongly felt by married female lecturers in the midst of the Covid-19 virus pandemic. Lecturers must carry out their duties from home, besides that they also have the task of taking care of children and husbands at home. Work-family conflict can be affected by work family conflict self-efficacy and spouse support. The purpose of this study was to see the relationship between the two variables (work-family conflict self-efficacy and spouse support) simultaneously on work-family conflict in married female lecturers. Subject totaled 21 female lecturers who worked as lecturers at a university. Researchers used the work family conflict, the work family conflict self-efficacy, and spouse support scale. The results obtained by R square = 0.428 means that work-family conflict self-efficacy and spouse support has a role as much as 42.8% in explaining work-family conflict. R value = 0.654; F = 6737; and p = 0.007 ?<0.05 where the hypothesis is accepted, meaning that there is a significant role between work-family conflict, self-efficacy, and spouse support for work-family conflict in married female lecturers at University X during work from home. The Beta value shows that spouse support has a higher value that affects work-family conflict than work-family conflict self-efficacy.
The impact of the Northern Sea Route development on economic security of the Far Eastern Federal District
Authors: ZHEBRIK El'za L.
Published: April 2022

Subject. The article addresses development prospects for the Northern Sea Route.
Objectives. The aim is to analyze the role of the Northern Sea Route in the economic security of the Far Eastern Federal District, assess the main directions of development of the Northern Sea Route in terms of economic growth priorities of the Far East.
Methods. The study employs methods of comparative and statistical analysis.
Results. The paper explores the impact of the Northern Sea Route development on economic security of the Far Eastern Federal District. It reveals areas for further development of the region, bearing in mind the factor of the Northern Sea Route.
Conclusions. The development of the Northern Sea Route should be based on the interests and priorities of constituent entities of the Far Eastern Federal District.
دور عناصر التدقيق التسويقي في الاداء التسويقي دراسة استطلاعية لاراء عينة من مديري الوحدات في مصانع انتاج المياه المعدنية في السليمانية
Authors: Saadon Omar Zakiya , Sleman Sadiq Darman
Published: April 2022

يهدف البحث الى تحديد العلاقة والتاثير لعناصر التدقيق التسويقي في الاداء التسويقي لمصانع انتاج المياه المعدنية في محافظة السليمانية، واستخدام في البحث المنهج الوصفي التحليلي لاختبار عينة عشوائية مكونة من (67) بوظائف مديري المصانع والاقسام والوحدات في المصانع المبحوثة عينة البحث،واستخدمت الاستبانة وسيلة في جمع البيانات لقياس ابعاد البحث عن طريق معرفة وجود الارتباط والتاثير بين عناصر التدقيق التسويقي والاداء التسويقي للمصانع المبحوثة للإجابة عن تساؤلات مشكلة البحث والوصول إلى الاهداف الموضوعة ،وقد تم استخدام عدد من الاساليب الاحصائية من اجل معالجة البيانات والوصول للنتائج باستخدام البرنامج الاحصائي (spss) ، وتوصل البحث الى مجموعة استنتاجات اهمها ( أن أكثر المتغيرات التي أخضعت للدراسة تأثيرا في الاداء التسويقي  كان  تدقيق النظم التسويقة ، ثم جاءت المتغيرات الأخرى  وهي تدقيق الانتاجية التسويقية، وتدقيق التنظيم التسويقي وتدقيق الاستراتيجية التسويقية، وتدقيق البيئة التسويقية متسلسلة التأثير فضلا عن تأثيرها كان تأثيرها معنويا) .
La Sustentabilidad Empresarial y el desempeño financiero
Authors: Saavedra García María Luisa
Published: April 2022

La sustentabilidad empresarial es un tema que cobra cada vez más importancia en un contexto en el cual las organizaciones son más conscientes de su responsabilidad ante la sociedad, en cuanto al uso de los recursos que toma de esta y del medioambiente para generar riqueza económica. El objetivo de este trabajo consistió en determinar la importancia de la sustentabilidad empresarial, los temas que la fundamentan haciendo énfasis en su relación con el desempeño financiero. Para lo cual se realizó una revisión documental que permitió desarrollar los temas: Sustentabilidad empresarial, Normas relacionadas con la sustentabilidad, Los fondos socialmente responsables, Informes de sustentabilidad y La sustentabilidad empresarial y el desempeño financiero. Se encontró que la sustentabilidad ha alcanzado una relevancia fundamental para el desempeño financiero, tal es así que cada vez más se han ido creando índices de sustentabilidad, que permiten a los grupos de interés evaluar el desempeño sustentable de las empresas e identificar las inversiones socialmente responsables, que emiten las mismas. En consonancia con esto, los informes de sostenibilidad empresarial, se han adoptado de manera voluntaria con el objetivo de dar a conocer las acciones sostenibles que realizan estos entes. Estos informes se encuentran en constante evolución y buscan cada vez más alinear la estrategia empresarial con las necesidades de la sociedad. Por último, se encontró que las investigaciones empíricas dan cuenta de una relación positiva entre la Sustentabilidad Empresarial y el Desempeño Financiero, mostrando así la imperativa necesidad de las empresas para alcanzar la sustentabilidad financiera.
Interpretation of the image of Tatiana Larina in Chinese Pushkin studies 1978 - 2010 .
Authors: Zhu Yan
Published: April 2022

The main attention in the article is paid to the peculiarities of the interpretation of the image of Tatiana Larina in Chinese Pushkin studies from 1978 to 2010. The article discusses various works of Chinese interpreters dedicated to the image of Tatiana. Based on the analysis of extensive material, an attempt is made to summarize the main features of the interpretation of Pushkin's heroine in China. The comparative-historical approach, methods of generalization, interpretation of the results were used in the study. In modern Pushkin studies, a lot of attention has been paid to the perception of A. S. Pushkin's work outside the homeland, especially in China, to a greater extent it concerns translation interpretation. And the analysis of Chinese literary works about a particular character вЂ” in this work about Tatiana Larina вЂ” is carried out for the first time. The scientific novelty of the study lies in the small knowledge of the problem of interpreting the image of Tatiana in China. In the course of the work, the peculiarities of the interpretation of the image of Tatiana in China were revealed вЂ” the fascination with the assessment of Tatiana's moral qualities, and at the same time вЂ” the neglect of the artistic nature of the Pushkin heroine. The results of the study contribute to the study of the image of Tatiana in Chinese Pushkin studies, and also contribute to a deep understanding of the image of the Russian woman in China. In addition, its results and conclusions can also be used in the study of intercultural relations between China and Russia, the study of the reception of Russian literature in China.
Modern Yakut horror story as a genre of urban post-folklore
Authors: Gogolev Anatolii Ignat'evich , Fedorova Aitalina Rodionovna
Published: April 2022

This article examines a special genre of Yakut oral literature вЂ“ modern Yakut "horror stories". This new genre was formed on the basis of traditional folklore in the late Soviet period during the era of active Urabanization processes in the Republic of Sakha (Yakutia) and is a genre of modern post-folklore. Proceeding from the point of view that any folklore transformations are indicators of the dynamics of public sentiment, an attempt was made to look at this genre as a reflection of some social experiences that support and are reflected in certain plots that remain more stable. The sources of the study were data from a survey conducted in 2018, in which 213 respondents took part. With the help of the obtained materials, some quantitative data were revealed, as well as the most popular and frightening motives of the modern Yakut horror story according to the respondents. The review of the most popular plots is carried out, the characteristics and regional features of the genre are given. The author comes to the conclusion that the Yakut horror story, arising during the period of urbanization processes, is the result of the decomposition of rural communications, and the characters of the modern chthonic spectrum differ from the traditional ones in their simplified appearance and universality in relation to global culture.
The technique for determining time for rescuing people from height with the help of an aerial ladder
Authors:   State Fire Academy of EMERCOM of Russia, SIBIRYAKOV M.V. , SOKOVNIN A.I. ,   State Fire Academy of EMERCOM of Russia, MIRONENKO R.V. ,   State Fire Academy of EMERCOM of Russia
Published: April 2022

Purpose. The article provides an analysis of people rescue procedure from height during a fire with the help of an aerial ladder, defines the speed characteristics for people to descend the ladder, analyzes the factors that influence the speed of descent, and offers the technique for determining time for rescuing people from height. Methods. To develop the calculation methods the authors of the article used the methods of statistical analysis, field observation, including the analysis of video recordings, and mathematical modeling. Findings. The search for records suitable for the conditions of the experiment resulted in ten videos containing elements of rescuing people from height. Video analysis made it possible to collect and generalize data on 27 descents during actual fire situations. The key parameter that needed to be assessed in the analysis is the speed of descent. Taking into account the method of obtaining data, the unit of measurement at the first stage was the number of steps of the ladder passed for unit (one minute) of time. After analyzing all the descents an average speed of descent was determined, as well as speeds of descent depending on various parameters, such as the gender of the escaping person, the way of descent, and various combinations of these parameters. Research application field. The obtained results can be used for methodological support of the process of pre-planning documents development in terms of determining the required means and forces for rescuing people from height with the help of aerial ladders. Conclusions. The technique proposed by the authors allows determining the necessary fire service means and forces to conduct rescue operations with the help of an aerial ladder.
Dermatological manifestations of arsenic exposure
Authors: Rajiv Shwetha V. , George Mamatha , Nandakumar Gopalapillai
Published: April 2022

Arsenic is a toxic metal which is found ubiquitous in nature. The past decade has witnessed a significant increase in global arsenic contamination with reports of arsenic-induced toxicity from several regions. Arsenic exposure can be from natural, industrial, or medicinal sources. Of this, natural groundwater contamination tops the list. Arsenic in toxic doses can cause both acute and chronic ill effects on the human body. Cutaneous and neurological changes are the earliest and the most common manifestations of chronic arsenic toxicity and hence provide a clue to early diagnosis. Dermatological manifestations may be the presenting symptom and include pigmentary changes, nail manifestations, arsenic keratosis, changes affecting distal extremities, and cutaneous malignancies. There is no established specific treatment for arsenic toxicity, though chelating agents have been tried with varying results.
Radical Alkynylations with EthynylBenziodoXolones: from Photocatalysis to Direct Excitation
Authors: Amos Stephanie G. E. , Waser Jerome
Published: April 2022

Ethynylbenziodoxolones (EBXs) have recently emerged as potent reagents for the alkynylation of radicals. Their combination with photocatalysis allows the synthesis of valuable alkynes at room temperature. Herein, we discuss two photomediated strategies for the synthesis of internal alkynes. The first transformation is a 1,2-oxyalkynylation of N- and O-alkenes using 4ClCzIPN as a photocatalyst. The second strategy makes use of EBXs as strong photooxidants allowing the oxidation of a variety of substrates with no need for a photocatalyst.
APAKAH ADA KORELASI ANTARA ASET BIOLOGIS DAN AUDITOR SWITCH TERHADAP AUDIT FEE DIMASA PANDEMI COVID-19?
Authors: Abdullah Sulthan Yusuf , R. Nelly Nur Apandi  , Agus Widarsono
Published: April 2022

Tujuan kajian adalah menguji dan menganalisis apakah aset biologis dan auditor switch berkorelasi terhadap audit fee dalam masa pandemi Covid-19 dengan sampel perusahaan agrikultur yang terdaftar di Bursa Efek Indonesia (BEI). Data yang dikumpulkan dianalisis secara deskriptif kuantitatif dan diikuti dengan analisis korelasi. Hasil kajian menunjukkan bahwa tidak ada satupun variabel yang berkorelasi terhadap audit fee. Penelitian ini hanya menggunakan dua variabel penjelas untuk menjelaskan audit fee. Untuk itu, kajian selanjutnya dapat menambah variabel lain untuk memperoleh hasil yang dapat digeneralisir. Implikasi penelitian adalah, diharapkan dapat menjadi referensi untuk penelitian selanjutnya.
PENGARUH LIKUIDITAS, STRUKTUR ASET, KEPEMILIKAN MANAJERIAL TERHADAP STRUKTUR MODAL DENGAN TINGKAT PERTUMBUHAN SEBAGAI MODERASI
Authors: Ramadhan Muhammad Rifqi , Mayangsari Sekar
Published: April 2022

This study aims to examine the impact of liquidity, asset structure, and managerial ownership on capital structure with growth rate as a moderating variable. This empirical analysis is based on secondary data on manufacturing businesses listed on the Indonesia Stock Exchange. Purposive sampling was used, resulting in as many as 74 firms being acquired. Data sources were acquired from www.idx.co.id and the observation period 2018-2020. According to the findings of this study, liquidity and management ownership have a negative correlation with capital structure, and Asset Structure does not correlate with capital structure. Moreover, the growth rate mitigates the negative correlation between liquidity on capital structure. The growth rate does not enhance the positive correlation between asset structure on capital structure and does not mitigate the negative correlation between managerial ownership on capital structure.
PENGARUH MANAJEMEN MODAL KERJA TERHADAP KINERJA PERUSAHAAN SEKTOR NON KEUANGAN
Authors: Hayundaniswara Allgamanora , Faisal Faisal
Published: April 2022

Penelitian ini menguji hubungan antara manajemen modal kerja, profitabilitas, nilai perusahaan, dan volatilitas return saham dengan menggunakan sampel 115 perusahaan non-keuangan yang terdaftar di database Bloomberg pada tahun 2018. Hasil kajian menemukan bahwa modal kerja bersih berpengaruh negatif dan signifikan terhadap profitabilitas, nilai perusahaan dan volatilitas return saham. Ini dapat dimaknai bahwa terkait manajemen modal kerja, manajer perlu membuat keputusan untuk meningkatkan profitabilitas mereka sambil mengendalikan risiko. Hasil kajian berkontribusi pada literatur tentang peran modal kerja terhadap profitabilitas, nilai perusahaan dan volatilitas return saham. Hasil kajian juga bermanfaat bagi manajer dalam mempertimbangkan manajemen modal kerja untuk mengatasi keputusan trade-off, meningkatkan profitabilitas sekaligus mengurangi potensi risiko perusahaan.
Co-Immobilization of Enzymes and Aptamers to create Self-Regenerating Ultrafiltration Membranes for Toxin Removal
Authors: Romero-Reyes Misael A. , Patterson Kristen , Heemstra Jennifer
Published: April 2022

Aptamer-functionalized membranes offer a promising platform for toxin removal, but regeneration of binding capacity requires heat and washing. Moreover, bound molecules can be eluted, resulting in recontamination. Here we report the tandem use of aptamers and enzymes to trap and degrade small-molecule contaminants, resulting in an autonomously self-regenerating purification system.
The Relationship between Energy Security, Exports and Economic Growth: The Case of the Middle East Countries
Authors: KARTAL Gökhan
Published: April 2022

In this study, it is aimed to examine the relationship between energy security, growth and exports for 16 Middle Eastern countries between 1980 and 2016 by taking into account the 4 dimensions of energy security (4 A's of energy security). Unlike other studies on the subject of Middle Eastern countries, this study covers more Middle Eastern countries and a wider period, and takes into account the cross-sectional dependency. The results of empirical analysis conducted by using second-generation unit-root and cointegration methods demonstrate that there is cointegration relationship between the variables. According to the results obtained from AMG estimator, which also considered cross-section dependence; the 1% increase in energy security risk level reduces the economic growth by approximately 0.66%, while the 1% increase in exports increases the economic growth by 0.41%. Finally, Granger non-causality test results demonstrate that there is a bi-directional causality relationship between variables. The results highlight the importance of policies to be implemented policies to ensure energy security such as choosing safe trade routes in oil and gas trade, ensuring the security of the major crossing points in the region, developing policies to decrease the share of energy revenues/expenses in the region economies, implementing policies for country and route diversification, ensuring energy efficiency and the use of renewable energy sources to prevent environmental pollution.
Student Perceptions of Skills Training Program as a Mean of Preparation for Nurse Profession Program
Authors: Mashfufa Erma Wahyu , Setyowati Lilis
Published: April 2022

The nursing profession must be pursued through higher education. Practice vehicles, such as hospitals require students to pass a skills test before they can practice. The Nursing Study Program, FIKES UMM, has implemented a matriculation program for students who will join the Nursing Profession. This activity has been carried out for a long time and has undergone several method changes to produce more effective outputs. However, there has never been an evaluation of how successful and valuable this program is for students. This type of research is a descriptive study because the researcher only observed Student' Perceptions Skills Training Programs in Preparing to Participate in Nursing Professional Education. The population in this study were all students of professional practice Nurses wave 20, a total of 50 respondents were taken by total sampling technique. The Dundee Ready Education Environment Measure (DREEM) questionnaire is appropriate for measuring the learning environment. Data analysis was carried out descriptively with percentages, tables, mean, and standard deviation.Â The result has shown that a score the DREEM questionnaireÂ  200 value indicates that there is a positive perception of the matriculation learning environment that has been carried out in preparation for entering professional practice, including the expertise of the teacher/facilitator.Â Students' perceptions of the matriculation program for the preparation of professional education are positive. On the other hand, to improve student skills to be more optimal, it is necessary to enhance the skills of facilitators and more supportive facilities and infrastructure
The Relationship of Stress Level with The Fair Production of Breast Milk on Nurses Who are Breastfeeding at Panti Waluyo Hospital Malang
Authors: Susmini Susmini
Published: April 2022

The nursing profession has an important role in providing health services in every health institution. Demands for professional services provide a workload that can increase stress on nurses, one of which can have an impact on breast milk production for nursing mothers. This study aims to determine the relationship between stress levels and the smooth production of breast milk in nursing nurses at Panti Waluya Hospital, Malang. This type of research is pre-experimmental with a cross sectional approach. The research sample used a simple random sampling technique with a total sample of 44 respondents. The research was conducted at Panti Waluya Hospital. Most of the 28 respondents (63.7%) had moderate stress levels, most of the respondents (61.3%) had non-fluent milk production. Based on the results of the Chi Square test, p-value + (0.036)<(0.05) is obtained so that Ho is rejected, meaning that there is a relationship between stress levels and the smooth production of breast milk for nurses at Panti Waluya Hospital, Malang. Nurses are expected to increase milk production by using stress coping and increasing nutritional intake.
Editorial
Authors: Junior Otoniel Fernandes da S , Silva Peixoto Filipe
Published: April 2022

Editorial do volume 5 n 1
The Secondary School Students’ Interest toward the TVET Programs: Demographic Differences
Authors: Azeem Nazia , Omar Muhd Khaizer , Rashid Abdullah Mat , Abdullah Arnida
Published: April 2022

Technical and Vocational Education and Training (TVET) has been globally recognized as one of the most vital subjects in any educational system. Pakistan is currently confronted with numerous challenges because of globalization and the emergence of new economic and social orders. To satisfy the updated requirements of economic trends, current educational systems must prioritize TVET as the most effective tool for satisfying globalization expectations. This study aimed to determine the demographic differences of secondary school students' interest toward TVET programs, which may be considered success factors for future enrollment initiatives. We perform an in-depth investigation into the relationship between students' interest in TVET programs and their demographic features, including gender, field of education, and geography. A total of 386 secondary school pupils in Pakistan participated in the study. A cross sectional research approach was employed. The mean, frequency, t-test, and ANOVA results were calculated on the collected data using the Statistical Package for the Social Sciences (SPSS). The findings indicate that students' perceptions of their interest in the TVET programs on all three dimensions (i.e. affection, cognition and conation) were somewhat poor. The t-test revealed a statistically significant difference in male and female students' interest in TVET programs. Male students were more interested in TVET programs compared to females. According to their field of education, the one-way ANOVA test revealed a substantial difference in their interest in TVET programs. Tukey HSD post-hoc analysis results suggest that there is a substantial disparity in students' interest in TVET programs in the field of education. The mean scores indicate that students in the humanities group were more interested in TVET programs, followed by bioscience, and computer science. The t-test reveals that students who live in urban regions have a higher level of interest compared to those who live in rural areas. The data gathered from this study provide insight onto the possible approaches academic institutions can take to prepare for and address current problems associated with introducing TVET programs in secondary schools. This paper argues for the need to integrate TVET programs in Pakistan which can promote transformative, lifelong learning and provide vital implications with recommendations for policy and practice.
The Effect of the Securities Transaction Tax Rate Cut on the Liquidity in KRX
Authors: Lee Woo Baik
Published: April 2022

This study evaluated the impact of the securities transaction tax rate cut implemented in 2019 on the liquidity of the stock market. The empirical results are summarized as follows. First, cutting the transaction tax rate affects trading volume rather than spread or price. Additionally, this liquidity improvement more strongly affects low liquid stocks in the period before the transaction tax rate cut. Second, in low liquid stocks that showed effects in trading volume, individuals and foreigners took the leadership in overall trading. Third, liquidity improvement persisted not only in the short term immediately after the transaction tax rate cut, but also until the second half of the sample period. These empirical results show the differing effect of the transaction tax on improving liquidity by liquidity level and a limited effect in low-liquidity stocks. As investors trading low-liquidity stocks with high tax elasticity were sensitive to the burden of transaction costs, the effect of transaction tax cuts was strong, while such effects could not be found in stocks with high liquidity. These empirical results provide practical implications for the level of transaction costs and the method of setting as a means to revitalize market liquidity.
Studi fenomenologi: Memaknai aktivitas dog walking sebagai fungsi rekreasi
Authors: Juliadilla Risa
Published: April 2022

Dog walking provides double-positive impacts to the owner and its dog both psychologically and physically. Dog walking with the aim of recreational activity can accommodate the dog owners and their pets with the good involvement that can perform as therapeutic to reduce stress. The research is qualitative within the perspective of phenomenology. The research question is how the pet owners understand dog walking as a recreational activity? This research aims to provide the reference on the Human-Animal Interaction implementation with the scope of psychology. Dog walking becomes a fun activity for the owner and performs proper stress relief. Dog walking for the pet owners is a sense to interact and communicate with their pets.
Pengaruh dukungan sosial dari orang tua terhadap motivasi belajar Mahasiswa komplasi Bima di kota Malang
Authors: Rizkan Muhamad , Diah Dewanti Ruparin , Priyanggasari Al Thuba Septa
Published: April 2022

This study aims to investigate the influence of social support for parents of students learning motivation Komplasi in Malang. The study population was all members of the Bima Komplasi student in Malang City. which numbered 134 students. Sampling in this study used simple random sampling technique and obtained 70 research samples from Komplasi Bima students. The results of data analysis that has been done with linear regression calculations obtained a value of 0,000. These results can be concluded that there is a positive influence between social support from parents and students' motivation to learn Komplasi Bima in Malang because the sig p value 0.05. Student motivation can not be increased if social support from parents is low and therefore it is expected that parents always give a sense of optimism and self-confidence to their children.
Faktor Determinan Penentu Minat Kewirausahaan pada Mahasiswa Universitas Merdeka Malang
Authors: Siswati Aris
Published: April 2022

Minat kewirausahaan pada mahasiswa dipengaruhi oleh banyak faktor antara lain dari dalam diriserta lingkungan sekitar. Tujuan dari kajian ini adalah untuk menentukan dampak faktor internaldan faktor eksternal terhadap minat kewirausahaan mahasiswa Universitas Merdeka Malang.Metode analisis yang dipergunakan ialah regresi berganda. Sampel dalam penelitian ini berjumlah110 responden. Teknik pengumpulan data dilakukan dengan menggunakan kuesioner kemudiandiolah dengan menggunakan SPSS. Kualitas data diuji dengan menggunakan uji validitas, ujireabilitas dan uji asumsi klasik. Hasil penelitian ini menunjukkan pada hipotesis pertama bahwafaktor internal (X1) menunjukkan pengaruh yang signifikan terhadap Minat Kewirausahaan (Y).Hipotesis kedua menunjukkan bahwa faktor eksternal (X2) tidak berpengaruh signifikan terhadapMinat Kewirausahaan (Y). Hipotesis ketiga bahwa faktor internal (X1) dan faktor eksternal (X2)secara bersama-sama mempunyai pengaruh yang signifikan Minat Kewirausahaan (Y) MahasiswaUniveritas Merdeka Malang.
Tingkat	Kemandirian	Keuangan	Daerah	dan	Implikasinya Terhadap Pertumbuhan Ekonomi Kabupaten Bojonegoro Tahun 2010-2019
Authors: Karenina Silvia , Andayani Krisna Dwi , Aditya Imanuel Andre , Wasil Mohammad
Published: April 2022

Tujuan penelitian ini adalah untuk menganalisis tingkat kemandirian keuangan daerah Kabupaten Bojonegoro dan hubungannya dengan tingkat kemandirian keuangan daerah dengan pertumbuhan ekonomi tahun 2009–2019. Hasil penelitian menunjukkan bahwa Kabupaten Bojonegoro memiliki tingkat kemandirian keuangan daerah yang sangat rendah sehingga dapat dikatakan tidak dapat melaksanakan otonomi daerah. Selain itu terdapat hubungan yang negatif dan tidak signifikan antara rasio untuk mengukur tingkat kemandirian keuangan daerah terhadap pertumbuhan ekonomi.
Analisis Pengaruh Pendapatan Asli Daerah, Dana Alokasi Khusus, dan Dana Alokasi Umum Terhadap Pertumbuhan Ekonomi di Kota Malang Tahun 2010- 2019
Authors: Sisilia Maria , Harsono Harsono
Published: April 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh Pendapatan Asli Daerah (PAD), Dana Alokasi Khusus (DAK) dan Dana Alokasi Umum (DAU) terhadap Pertumbuhan Ekonomi di Kota Malang tahun 2010-2019. Penelitian dilakukan di wilayah Kota Malang dengan menggunakan data sekunder tahun 2010-2019. Pengumpulan data dilakukan melalui dokumentasi yaitu pengumpulan data sekunder dengan sumber-sumber tertulis berupa laporan keuangan yang ada di Dinas Pendapatan Daerah Kota Malang. Analisis data yang dilakukan menggunakan Analisis Deskriptif dan Analisis Regresi Linier Berganda. Berdasarkan hasil penelitian menunjukkan bahwa PAD, DAK dan DAU berpengaruh signifikan terhadap Pertumbuhan Ekonomi di Kota Malang tahun 2010-2019.
Penguatan Peran Sektor Keuangan bagi Percepatan Pemerataan Kesejahteraan
Authors: Nasution Lokot Zein
Published: April 2022

Kebijakan untuk mengoptimalkan peranan sektor keuangan bagi penurunan angka kemiskinan dan ketimpangan seringkali kurang berhasil. Hal ini diakibatkan oleh lemahnya daya analisis untuk memetakan akar masalah penyebab kemiskinan. Padahal, peranan sektor keuangan sangat dibutuhkan dalam menyediakan aksesibilitas jasa layanan keuangan terutama kepada masyarakat miskin. Mengoptimalkan peran sektor keuangan dalam menciptakan model keuangan yang inklusif diyakini mampu menciptakan pemerataan kesejahteraan yang bisa bertahan dalam jangka panjang. Berdasarkan latar belakang tersebut, tulisan ini bertujuan untuk mengeksplorasi bagaimana mekanisme untuk mengoptimalkan peranan sektor keuangan dalam mempercepat pemerataan kesejahteraan. Berdasarkan metode literature review, hasil beragam studi empiris menemukan bahwa optimalisasi peranan sektor keuangan harus bisa mengkonstruksi akar masalah penyebab kedalaman dan keparahan kemiskinan. Strategi yang bisa dikembangkan adalah meningkatkan edukasi dan literasi keuangan di perdesaan, menciptakan ekosistem keuangan yang kondusif, dukungan politik, dan perbaikan kelembagaan bagi masing-masing pelaku sektor keuangan, khususnya agar mampu menciptakan skema pemberdayaan pasca aksesibilitas keuangan diberikan. Semua skema tersebut menjadi syarat untuk mendorong inovasi atas produk dan jasa layanan keuangan yang yang sesuai dengan karakteristik masyarakat sasaran, sehingga diharapkan mampu mempercepat pemerataan kesejahteraan dalam jangka panjang.