bluuebunny/crossref_metadata_2025 huggingface dataset:
Novel role of mortalin in attenuating HIV-1 Tat-mediated astrogliosis
Authors: Priyanka  , Wadhwa Renu , Chaudhuri Rituparna , Nag Tapas Chandra , Seth Pankaj
Published: September 2020

Background

In human immunodeficiency virus-1 (HIV-1) infection, activation of astrocytes induces imbalance in physiological functions due to perturbed astrocytic functions that unleashes toxicity on neurons. This leads to inflammatory response finally culminating into neurocognitive dysfunction. In neuroAIDS, HIV-1 protein, transactivator of transcription (Tat) is detected in the cerebrospinal fluid of infected patients. Mortalin, a multifunctional protein, has anti-inflammatory role following its activation in various stress conditions. Recent studies demonstrate downregulation of mortalin in neurodegenerative diseases. Here, we explored the mechanisms of mortalin in modulating HIV-1 Tat-mediated neuroinflammation.

Methods

Expression of mortalin in autopsy section in normal and diseased individuals were examined using immunohistochemistry. To decipher the role of mortalin in HIV-1 Tat-induced activation, human fetal brain-derived astrocytes were transiently transfected with Tat and mortalin using expression vectors. HIV-1 Tat-mediated damage was analyzed using RT-PCR and western blotting. Modulatory role of mortalin was examined by coexpressing it with Tat, followed by examination of mitochondrial morphodynamics using biochemical assay and confocal and electron microscopy. Extracellular ATP release was monitored using luciferase assay. Neuroinflammation in astrocytes was examined using flow cytometry, dye based study, immunocytochemistry, immunoprecipitation, and western blotting. Indirect neuronal damage was also analyzed.

Results

HIV-1 Tat downregulates the expression of mortalin in astrocytes, and this is corroborated with autopsy sections of HIV-1 patients. We found that overexpression of mortalin with Tat reduced inflammation and also rescued astrocytic-mediated neuronal death. Using bioinformatics, we discovered that binding of mortalin with Tat leads to Tat degradation and rescues the cell from neuroinflammation. Blocking of proteosomal pathway rescued the Tat degradation and revealed the ubiquitination of Tat.

Conclusion

Overall, our data demonstrated the protective role of mortalin in combating HIV-1 Tat-mediated damage. We also showed that mortalin could degrade Tat through direct binding with HIV-1 Tat. Overexpression of mortalin in the presence of Tat could significantly reduce cytotoxic effects of Tat in astrocytes. Indirect neuronal death was also found to be rescued. Our in vitro findings were validated as we found attenuated expression of mortalin in the autopsy sections of HIV-1 patients.
Langat virus infection affects hippocampal neuron morphology and function in mice without disease signs
Authors: Cornelius Angela D. A. , Hosseini Shirin , Schreier Sarah , Fritzsch David , Weichert Loreen , Michaelsen-Preusse Kristin , Fendt Markus , Kröger Andrea
Published: September 2020

Background

Tick-borne encephalitis virus (TBEV) is an important human pathogen that can cause the serious illness tick-borne encephalitis (TBE). Patients with clinical symptoms can suffer from severe meningoencephalitis with sequelae that include cognitive disorders and paralysis. While less than 30% of patients with clinical symptoms develop meningoencephalitis, the number of seropositive individuals in some regions indicates a much higher prevalence of TBEV infections, either with no or subclinical symptoms. The functional relevance of these subclinical TBEV infections and their influence on brain functions, such as learning and memory, has not been investigated so far.

Methods

To compare the effect of low and high viral replication in the brain, wildtype and Irf-7−/− mice were infected with Langat virus (LGTV), which belongs to the TBEV-serogroup. The viral burden was analyzed in the olfactory bulb and the hippocampus. Open field, elevated plus maze, and Morris water maze experiments were performed to determine the impact on anxiety-like behavior, learning, and memory formation. Spine density of hippocampal neurons and activation of microglia and astrocytes were analyzed.

Results

In contrast to susceptible Irf-7−/− mice, wildtype mice showed no disease signs upon LGTV infection. Detection of viral RNA in the olfactory bulb revealed CNS infections in wildtype and Irf-7−/− mice. Very low levels of viral replication were detectable in the hippocampus of wildtype mice. Although wildtype mice develop no disease signs, they showed reduced anxiety-like behavior and impaired memory formation, whereas Irf-7−/− mice were not affected. This impairment was associated with a significant decrease in spine density of neurons in the hippocampal CA1 region of wildtype mice. Microglia activation and astrogliosis were detected in the hippocampus.

Conclusion

In this study, we demonstrate that subclinical infections by viruses from the TBEV-serogroup affected anxiety-like behavior. Virus replication in the olfactory bulb induced far-reaching effects on hippocampal neuron morphology and impaired hippocampus-dependent learning and memory formation.
Spatially confined vector fields at material-induced resonances in near-field-coupled systems
Authors: Aminpour Hamed , Eng Lukas M. , Kehr Susanne C.
Published: September 2020

Local electric fields play the key role in near-field optical examinations and are especially appealing when exploring heterogeneous or even anisotropic nano-systems. Scattering-type near-field optical microscopy (s-SNOM) is the most commonly used method applied to explore and quantify such confined electric fields at the nanometer length scale: while most works so far did focus on analyzing the z-component oriented perpendicular to the sample surface under p-polarized tip/sample illumination only, recent experimental efforts in s-SNOM report that material resonant excitation might equally allow to probe in-plane electric field components. We thus explore this local vector-field behavior for a simple particle-tip/substrate system by comparing our parametric simulations based on finite element modelling at mid-IR wavelengths, to the standard analytical tip-dipole model. Notably, we analyze all the 4 different combinations for resonant and non-resonant tip and/or sample excitation. Besides the 3-dimensional field confinement under the particle tip present for all scenarios, it is particularly the resonant sample excitations that enable extremely strong field enhancements associated with vector fields pointing along all cartesian coordinates, even without breaking the tip/sample symmetry! In fact, in-plane (s-) resonant sample excitation exceeds the commonly-used p-polarized illumination on non-resonant samples by more than 6 orders of magnitude. Moreover, a variety of different spatial field distributions is found both at and within the sample surface, ranging from electric fields that are oriented strictly perpendicular to the sample surface, to fields that spatially rotate into different directions. Our approach shows that accessing the full vector fields in order to quantify all tensorial properties in nanoscale and modern-type materials lies well within the possibilities and scope of today’s s-SNOM technique.
Ultra-thin and high-efficiency full-space Pancharatnam-Berry metasurface
Authors: Mao Ruiqi , Wang Guangming , Cai Tong , Liu Kaiyue , Wang Dengpan , Wu Borui
Published: September 2020

Full-space metasurfaces (MSs) attract significant attention in the field of electromagnetic (EM) wave manipulation due to their advantages of functionality integration, spatial integration and wide applications in modern communication systems. However, almost all reported full-space metasurfaces are realized by multilayer dielectric cascaded structures, which not only has the disadvantages of high cost and complex fabrication but also is inconvenient to device integration. Thus, it is of great interest to achieve high-efficiency full-space metasurfaces through simple design and easy fabrication procedures. Here, we propose a full-space MS that can efficiently manipulate the circularly polarized (CP) waves in dual frequency bands by only using a single substrate layer, the reflection and transmission properties can be independently controlled by rotating the optimized meta-structures on the metasurface. Our full-space metasurface has the potential to design multifunctional devices. To prove the concept, we fabricate the device and measured it in microwave chamber. For the reflection mode, our metasurface can behave as a CP beam splitter at the frequency of f1 = 8.3 GHz and exhibit high efficiencies in the range of 84.1%–84.9%. For the transmission mode, our metasurface acts as a meta-lens at the frequency of f2 = 12.8 GHz for the LCP incidence, and the measured relative efficiency of the meta-lens reaches about 82.7%. Our findings provide an alternative way to design full-space metasurfaces and yield many applications in EM integration systems.
Switchable broadband and wide-angular terahertz asymmetric transmission based on a hybrid metal-VO2 metasurface
Authors: Dong Xiaoxiang , Luo Xiaoqing , Zhou Yixuan , Lu Yuanfu , Hu Fangrong , Xu Xinlong , Li Guangyuan
Published: September 2020

We propose a switchable broadband and wide-angular terahertz asymmetric transmission based on a spiral metasurface composed of metal and VO2 hybrid structures. Results show that asymmetric transmission reaching up to 15% can be switched on or off for circularly polarized terahertz waves when the phase of VO2 transits from the insulting state to the conducting state or reversely. Strikingly, we find that relatively high asymmetric transmission above 10% can be maintained over a broad bandwidth of 2.6–4.0 THz and also over a large incident angular range of 0°–45°. We further discover that as the incident angle increases, the dominant chirality of the proposed metasurface with VO2 in the conducting state can shift from intrinsic to extrinsic chirality. We expect this work will advance the engineering of switchable chiral metasurfaces and promote terahertz applications.
Recognition of coal from other minerals in powder form using terahertz spectroscopy
Authors: Deng Jingjing , Ornik Jan , Zhao Kai , Ding Enjie , Koch Martin , Castro-Camus Enrique
Published: September 2020

Currently a significant fraction of the world energy is still produced from the combustion of mineral coal. The extraction of coal from mines is a relatively complex and dangerous activity that still requires the intervention of human miners, and therefore in order to minimize risks, automation of the coal mining process is desirable. An aspect that is still under investigation is potential techniques that can recognize on-line if the mineral being extracted from the mine is coal or if it is the surrounding rock. In this contribution we present the proof of concept of a method that has potential for recognition of the extraction debris from mining based on their terahertz transmission.
Google Traffic sebagai Masukan Kebijakan Transportasi Perkotaan (Studi Kasus: Kota Bandar Lampung)
Authors: Ibad Muhammad Zainal , Sulistyorini Rahayu , Rahmah Chania
Published: September 2020

Congestion in urban areas is vulnerable because of the impact of the growth of activities and an increasingly specialized and complex economy. For this reason, it is necessary to formulate a good urban transportation policy to accommodate increased urban transportation needs. Google Traffic is a feature found on Google Maps to see the level of congestion in an area. Google Traffic can detect an area with red, yellow or green indications through the principle of Real Time Data using data from the Global Positioning System (GPS). This study wanted to see how the use of the Google Traffic Feature as input to urban transportation policies by looking at existing urban transportation policies, analyzing the movement system model on Google Traffic, and analyzing the development of Google Traffic model policies, which would be useful for the development of Urban Transportation Policies, especially Bandar Lampung City as a case study.
The sharper form of a Brunn-Minkowski type inequality for boxes
Authors: TINAZTEPE Gültekin , KEMALİ Serap , SEZER Sevda , EKEN Zeynep
Published: September 2020

In this study, the Brunn-Minkowski inequality for boxes is studied and a sharper version of this inequality is derived by performing the results based on abstract convexity.
ISPARTA SÜLEYMAN DEMİREL ÜNİVERSİTESİ HASTANESİNDE ERİŞKİNLERDE DEMİR EKSİKLİĞİ ANEMİSİ PREVALANSI VE ETYOLOJİK FAKTÖRLERİN DEĞERLENDİRİLMESİ
Authors: KAPLANOĞLU Emre , ÖZBALCI Demircan , ALANOĞLU Emine Güçhan , GÜRDAL Osman
Published: September 2020

Amaç
Demir eksikliği anemisi (DEA) dünyada ve ülkemizde
en sık görülen hastalıktır ve etyolojisinde birçok neden
yer almaktadır. Çalışmamızın amacı DEA’ nın Süleyman
Demirel Üniversitesi Tıp Fakültesi hastanesine
başvuran hastalarda retrospektif olarak prevalansını
ve etyolojisini araştırmaktır.
Gereç ve Yöntem
Çalışmaya Nisan 2017 - Kasım 2017 arasında Süleyman
Demirel Üniversitesi Tıp Fakültesi İç Hastalıkları
polikliniğine başvuran ve en az tam kan sayımı, ferritin,
vitamin B12, folik asit değerleri istenmiş 18-65
yaş arasındaki toplam 1000 hasta alınmıştır. Hastalara
ait cinsiyet, yaş, kadınlarda menopozal durum, ek
hastalıkları ve etyolojik faktörleri kaydedilmiştir. Bütün
hastaların hemoglobin, hematokrit, MCV, RDW, lökosit,
trombosit, ferritin, vitamin B12, folik asit düzeyleri
kayıt altına alınmıştır.Kadınlarda hemoglobin 12 g/dl
altında, erkeklerde 13 g/dl altında (WHO’ya göre) ve
ferritin 15 ng/ml altında (romatizmal hastalığı olanlarda
100 ng/ml’ nin altında) olanlar DEA olarak kabul
edilmiştir. DEA’ si saptanan hastalarda etyolojik faktörleri
incelemek için; diyetle demir alımı, kadınlarda
menstrüel kanama, hemoroid, peptik ülser, mide operasyonu,
gastrit, malignite gibi sebepler araştırılmıştır.
Başvuruda saptanan ek hastalıklar sırasıyla kronik
karaciğer hastalığı, kronik böbrek hastalığı, akciğer
hastalıkları, bağ dokusu hastalıkları, endokrinolojik
hastalıklar, hipertansiyon, diabetes mellitus, maligniteler,
hemoglobinopatiler ve inflamatuar bağırsak hastalıkları
olarak gruplandırılmıştır.
Bulgular
Çalışmamızdaki kadınların % 25’ inde, erkeklerin %
7,4’ inde DEA saptanırken tüm hastalarda ise DEA
prevalansını % 20,3 olarak bulduk. DEA etyolojisi ise
kadınlarda en sık neden menoraji iken erkeklerde
gastrit olarak saptandı. Çalışmamızda DEA olan erkeklerin
% 55 ve kadınların % 34,4’ ünde ise etyoloji
saptanmadı.
Sonuç
Demir eksikliği anemisi ile ilişkili prospektif, pika ve
parazitoz taramalarını da içeren, toplumsal kökenli
çalışmalar yapılması gerekmektedir.
Influence of induction heating of injection molds on reliability of electrical connectors
Authors: Mrozek Krzysztof , Muszyński Paweł , Poszwa Przemysław
Published: September 2020

Continuous increase in demand for electricity causes that electrotechnical industry is relentlessly under pressure of technological development. It is necessary to reduce costs while
increasing a reliability of manufactured products. Common miniaturization of products
mounted in land vehicles, vessels and airplanes along with limitation of their weight requires
the use of innovative production methods. This publication presents the problem of exploitation related with reliable assembly and disassembly of rail-mounted electrical connectors.
In order to improve the reliability of injected electrical connector housings, the authors
proposed the selective induction heating technology as a heating method of injection mould.
To reveal the origin of the problem, in case of this work, the simulation studies of filling the
mould cavity were carried out. They show an incorrect localization of polymer streams weld
line. Then the results of the simulation and induction heating experiment are presented. They
were necessary for the proper design and make of the injection mould. In the final stage, the
experimental tests of the manufactured housings assembly and disassembly were performed
in conditions corresponding to the actual conditions. The obtained results show, that selective induction heating technology has significantly improved the reliability of rail-mounted
electrical connector housings.
Fast bearing fault diagnosis of rolling element using Lévy Moth-Flame optimization algorithm and Naive Bayes
Authors: Sun Shuang , Przystupa Krzysztof , Wei Ming , Yu Han , Ye Zhiwei , Kochan Orest
Published: September 2020

Fault diagnosis is part of the maintenance system, which can reduce maintenance costs,
increase productivity, and ensure the reliability of the machine system. In the fault diagnosis
system, the analysis and extraction of fault signal characteristics are very important, which
directly affects the accuracy of fault diagnosis. In the paper, a fast bearing fault diagnosis
method based on the ensemble empirical mode decomposition (EEMD), the moth-flame
optimization algorithm based on Lévy flight (LMFO) and the naive Bayes (NB) is proposed,
which combines traditional pattern recognition methods meta-heuristic search can overcome
the difficulty of selecting classifier parameters while solving small sample classification
under reasonable time cost. The article uses a typical rolling bearing system to test the actual performance of the method. Meanwhile, in comparison with the known algorithms and
methods was also displayed in detail. The results manifest the efficiency and accuracy of
signal sparse representation and fault type classification has been enhanced.
Strength tests of polymer-glass composite to evaluate its operational suitability for ballistic shield plates
Authors: Szymczak Tadeusz , Kowalewski Zbigniew
Published: September 2020

The paper concerns the study of polymer-glass composite under tensile loading in order to
determine changes in the tensile characteristics. Mechanical properties and features of damage zones important for operation and assessment of the technical conditions of the components made of this material are considered. Selected details of the experimental technique
used are presented. The tensile characteristics of the polymer-glass composite are given.
They were determined using specimens taken from various directions, with the main focus
on the Young's modulus, elastic limit, yield point and ultimate tensile strength. An influence
of the number of reinforcement layers, percentage content of the glass fibres as well as the
resin quantity, on the mechanical parameters, are discussed.
Sensory quality of tilapia hamburger (oreochromis niloticus) with addition of soybean residue (okara)
Authors: Oliveira Rafaela Bergmann Strada de , Della Lucia Flávia , Ferreira Eric Batista , Castilho Dayana Aparecida Queiroz , Carvalho Estella Peixoto , Guimarães Isabela Garcia da Cunha
Published: September 2020

This paper intends to develop and evaluate the sensory quality of tilapia hamburgers with addition of okara flour, aiming to develop a product of good protein quality, rich in fiber, low cost and easy access to the population. Okara flour was added at different concentrations (0, 5, 10, 15, 20 and 25%) to hamburgers and then these were subjected to analysis of acceptability (9-point hedonic scale). The averages for all evaluated parameters varied between 5.02 and 7.5, within the range of "indifferent" to "liked moderately". The highest means were found for formulations with 10 and 15% of okara, indicating the okara amount that provides better sensory quality of the product. These results confirm the tendency to seek products with higher nutritional value, and tilapia hamburger with added okara as an alternative to market, aiming at making fish and soybean increasingly present in the eating habits of the population.
Analisis Faktor-Faktor Yang Mempengaruhi Literasi Keuangan Pada Petani Tanaman Pangan dan Holtikultura di Kabupaten Maros Sulawesi Selatan
Authors: Anwar Anas Iswanto , Putri Rezki , Sabir Sabir
Published: September 2020

This study aims to determine the effect of demographic characteristics on the level of financial literacy of food crops and horticulture farmers in Camba sub-district in South Sulawesi Province. This research data obtained from the questionnaire (primary) and few observations and direct interviews with Camba sub-district farmers. This study uses a multiple linear regression analysis method. The results of the analysis concluded that the demographic characteristic variables consisting of income level, age, education level, risk preference dummy, and distance to financial institutions simultaneously had a significant effect on financial literacy variables with a five percent significance level. Income level, education level, risk preference partially had a positive and significant effect on the variable financial literacy. Distance to financial institutions had a negative and significant effect while age doesn’t have a significant effect on financial literacy. Of 43.8 percent from the variation in financial literacy variables is explained by the independent variables used in this model, while the rest of 56.2 percent is explained by other variables.
Pembentukan Mata Uang Tunggal Kawasan ASEAN
Authors: Cholifah Nurul , Wahyuningsih Diah
Published: September 2020

Financial integration is the last step that can be done to achieve economic integration. One condition that must be met before the implementation of financial integration is the existence of the optimal currency area (OCA) criteria. The purpose of this study: 1) to find out the closeness of the currency to changes in the bilateral exchange rate as a supporter in the possibility of forming a single currency in the ASEAN region, 2) to analyze the chosen anchor currency which has a positive influence (appreciation) on the local currency of the ASEAN region as a currency single money region. This study uses annual real output data, size of GDP ratio, bilateral trade, differences in the composition of trade, and the exchange rate throughout of 1995-2018 period. The analytical method used is panel data test. The results showed that the currencies of ASEAN countries did not yet have the closeness of forming a single currency in the ASEAN region. Meanwhile, to determine the appropriate anchor currency to be used as a shared currency, namely SGD (Singapore Dollar) empirically has a positive influence (appreciation) in the ASEAN region compared to RMB, JPY, Euro, or USD. Therefore SGD can be proposed as an anchor currency for ASEAN countries.
ANALISIS PERILAKU PENGENDARA DAN JARAK PANDANG HENTI SEPEDA MOTOR MATIC
Authors: Buchari Erika , Junanta Ahmad Gilang Dwi
Published: September 2020

The growth of Matic-Motorcycle in Indonesia is increased steeply lately. According to Assosiasion of Indonesian Motorcycle Industry, AISI the sales of matic motorcycle have achieved 75,49% (3,639,000) of the wholesaler 4,821,000. In fact, motorcycle users do not realize that automatic motorcycle’s characteristics especially braking distance are different with those of non-automatic motorcycles. The different way of riding can cause uncontrolled vehicles during braking, when promptly change speed either faster or slower. Stopping sight distance is the distance needed by riders in order to stop their moving vehicles after seeing the obstacles in the front. This research is seeking to know the behavior of motorcycle users and stopping sight distance that is ideal for the users of automatic motorcycles. Multi linear Regression model is made to find out the relationship between stopping sight distance and other variables such as speed, machine capacity, type of brakes etc. From this model, it can be derived the ideal stopping sight distance which is affected by speed, machine capacity, type of front brakes.

Perkembangan sepeda motor matic di Indonesia mengalami pertumbuhan yang sangat pesat beberapa tahun belakangan ini. Menurut data dari asosiasi industri sepeda motor Indonesia( AISI,2015) penjualan sepeda motor matic mengalami pertumbuhan yang sangat pesat dibandingkan dan motor bebek dan sport, yaitu 75,49% (3,639 juta matic dari penjualan 4,821 juta motor keseluruhan). Fakta di lapangan, pengguna tidak menyadari beda karakteristik kendaraan motor matic dengan non matic. Perbedaan ini mengakibatkan tidak terkontrolnya kecepatan kendaraan dimana seringnya terjadi perubahan percepatan dan perlambatan pada kendaraan tersebut. Jarak pandangan henti adalah jarak yang dibutuhkan oleh pengendara untuk menghentikan kendaraannya yang bergerak setelah melihat adanya rintangan pada lajur jalannya. Penelitian ini ingin mengetahui perilaku pengendara dan jarak pandang henti yang ideal bagi pengendara sepeda motor matic. Model Multi linear Regression hubungan Jarak pandangan henti dengan variable kecepatan, kapasitas mesin dan jenis rem diteliti. Hasilnya diperoleh jarak henti ideal yang dipengaruhi oleh kecepatan, kapasitas mesin, dan jenis rem depan.
FAKTOR SOSIAL PSIKOLOGIS PERILAKU MENGGUNAKAN HELM PADA PENGENDARA SEPEDA MOTOR: STUDI DI WILAYAH DEPOK
Authors: Guritnaningsih Guritnaningsih , Maulina Dewi , Siregar Ermanda
Published: September 2020

An impact to the head when it is not protected by a helmet generally results in brain injury and may result in death. The current study aimed to identify the psychosocial factors that play a role in helmet wearing behavior among motorcyclists. A mixed-method approach was used on a sample of active motorcycle riders in Depok area who are in early and middle adulthood. Data were collected using a questionnaire and a Focused Group Discussion. The results showed a difference between adults under 25 years and adults over 25 years in their attitude towards helmet use. Level of education and attitude were also both found to be significant predictors of helmet use. Findings of the study imply the need for a more structured effort to build a positive attitude towards helmet use, especially among younger motorcycle riders.

Benturan pada kepala yang tidak dilindungi oleh helm umumnya menyebabkan kerusakan pada otak dan berujung pada kematian. Penelitian ini bertujuan untuk mengidentifikasi faktor sosial psikologis yang berperan pada perilaku menggunakan helm pada pengendara sepeda motor. Pendekatan yang digunakan adalah mixed-method, dengan sampel pengendara sepeda motor aktif di wilayah Depok, yang berusia dewasa muda dan dewasa menengah. Pengumpulan data dilakukan dengan menggunakan kuesioner dan diskusi kelompok terfokus (Focus Group Discussion) . Hasil penelitian ini menunjukkan bahwa terdapat perbedaan sikap terhadap penggunaan helm antara pengendara sepeda motor berusia di bawah 25 tahun dan yang berusia di atas 25 tahun . Ditemukan juga bahwa tingkat pendidikan dan sikap merupakan prediktor yang signifikan terhadap penggunaan helm. Implikasi penelitian ini adalah dilakukannya upaya yang lebih terstruktur untuk pembentukan sikap positif pada para pengendara sepeda moto r terutama pengendara usia muda.
FACTORS AFFECTING HIGH SCHOOL AND UNIVERSITY STUDENTS TO SPEEDING
Authors: Dewanti Dewanti , Harmanto Jan Prabowo
Published: September 2020

This study aims to find factors influencing students to do speeding in Yogyakarta Special Region. 179 respondents filled in on-line and off-line questionnaires to determine options or probabilities of speeding up on a variety of different road / environmental conditions. Cross tab tests and ordered logistic regression are adopted to analyze influencing factors (both internal and external). 3 of 18 predictor variables do not affect speeding behavior, and those are driving experience, road separator, and speed limit signs. While the age, education, and police presence are negatively correlated with speeding behavior, it means that the older, and the higher a person's education and the presence of police, people tend not to have speeding behavior. The other research result is the level order of the influencing factor of speeding (predictor variables).

Penelitian ini bertujuan menemukan faktor – faktor yang mempengaruhi pelajar dan mahasiswa melakukan ‘speeding’ atau ngebut di Daerah Istimewa Yogyakarta. Sebanyak 179 responden mengisi kuesioner on-line maupun off-line untuk mengetahui pilihan-pilihan atau probabilitas melakukan ngebut untuk berbagai kondisi jalan/lingkungan yang berbeda. Uji cross tab dan regresi logistic ordinal digunakan untuk menganalisis factor-faktor (baik internal maupun eksternal) yang berpengaruh. Dari 18 variabel predictor, 3 diantaranya tidak berpengaruh, yaitu: pengalaman berkendara, pemisah jalan dan rambu batas kecepatan. Sementara variable usia, pendidikan dan keberadaan polisi berkorelasi negative terhadap perilaku ngebut, artinya semakin bertambah usia, dan makin tinggi pendidikan seseorang serta adanya polisi mendorong orang untuk tidak ngebut. Dihasilkan juga urutan tingkat pengaruh masing-masing factor (variable predictor)
MODELING THE PROBABILITY OF SPEEDING BEHAVIOUR AND ACCIDENT INVOLVEMENT USING BINARY LOGISTIC REGRESSION IN EAST JAVA PROVINCE
Authors: Kriswardhana Willy , Sulistyono Sonya , Ervina Iin , Supriyanto Dadang , Hayati Nunung Nuring , Wicaksono Achmad , Mujanarko Sri Wiwoho , Ramadhani Raka Aminul
Published: September 2020

Driving at high speed has negative consequences, namely, the high number of accidents. Several factors have been considered as causes of the increasing severity of victims of traffic accidents, such as a human, vehicle, and environmental factors. The risky driving behavior factor is a factor that needs to be considered in traffic safety studies. This study aims to determine the probability model of speeding behavior based on several driver characteristics and their relationship to accident involvement. This study used a binary logistic regression method to determine the probability of driving behavior exceeding the speed limit and accident involvement. The results showed that the younger a person is, the higher the probability of breaking the maximum speed limit. Furthermore, driving experience also shows a similar trend, where the longer the driving experience of someone, the less likely it is to be involved in an accident. Directions for further research are also presented.

Berkendara dengan kecepatan tinggi mempunyai konsekuensi negatif, yaitu tingginya angka kecelakaan. Beberapa faktor telah dipertimbangkan sebagai penyebab dari peningkatan tingkat keparahan korban kecelakaan lalulintas. Faktor tersebut seperti faktor manusia, kendaraan, dan lingkungan. Faktor perilaku berkendara yang berbahaya, menjadi faktor yang perlu diperhatikan dalam kajian keselamatan lalulintas. Penelitian ini bertujuan untuk mengetahui model probabilitas pada perilaku speeding berdasarkan beberapa karakteristik pengendara, serta hubungannya dengan keterlibatan kecelakaan. Penelitian ini menggunakan metode regresi logistik biner untuk mengetahui probabilitas perilaku berkendara melebihi batas kecepatan dan keterlibatan kecelakaan. Hasil penelitian menunjukkan bahwa semakin muda usia seseorang, maka semakin tinggi probabilitasnya dalam melanggar batas kecepatan maksimum. Lebih lanjut diperlihatkan bahwa pengalaman mengemudi juga menunjukkan tren yang serupa. Pengalaman mengemudi seseroang, yang lebih lama akan memperkecil kemungkinan dalam keterlibatan kecelakaan. Arahan untuk penelitian selanjutnya juga ditampilkan.
The urgency of asset confiscation sanction in tax crimes
Authors: Margono Rudi , Nurjaya I Nyoman , Negara Tunggul Anshari Setia , Hadi Heru
Published: September 2020

Law Number 16 of 2009 concerning General Provisions and Tax Procedures (UU KUP), regulates administrative sanctions and criminal sanctions. The KUP Law method does not yet regulate how to save the loss of state revenue because it does not regulate the implementation of criminal fines, the legal implications of different decisions that cause legal uncertainty, injustice and have not provided benefits, especially in an effort to collect taxes. The purpose of this paper is to find out, analyze, and find the urgency of regulating criminal sanctions for the deprivation of assets in tax crime. This study is normative legal research with a legislation approach, historical approach, comparative law approach, conceptual approach, and case approach. The legal materials used are primary and secondary legal materials. Analysis of legal material is done with a descriptive perspective. The results of this study indicate that the inclusion of fine sanctions in the KUP Act turns out to lead to different interpretations resulting in legal uncertainty and does not provide economic benefits for the state in law enforcement, because the sanctions for fines are not complemented by implementing sanctions in the form of additional criminal sanctions in the form of confiscation of assets belonging to the defendant or an act (maatregel) in the form of requiring improvement of corporate governance in accordance with good corporate governance or placement of a legal company, where an economic crime is committed under a certain period of time, so that in the future the KUP Act, additional sanctions or actions to strengthen / complete in the future criminal sanctions for fines.
Influence of work specialization on employee development
Authors: Kimani Tabithah Kabui , Gesimba Paul Omato , Gichuhi David
Published: September 2020

There are visible challenges with employee development at Telkom Kenya where employees remain in one position for many years with some remaining in the same position until their retirement. Anecdotal evidence suggests that this problem could be linked to the design of the organization, but no systematic study has been conducted to ascertain this claim. This study, therefore, sought to determine the influence of work specialization on employee development at Telkom Kenya Nakuru Branch. The study was guided by the Axiomatic Theory of Organizations. It made use of the correlational research design where all the 51 employees of the Telkom Kenya Nakuru Branch were involved in the census study. Questionnaires were used to collect quantitative data from operational staffs while interview guides were used to gather qualitative data from heads of departments. Quantitative data were analyzed using frequencies, percentages, means, and the multiple regression techniques while qualitative data were analyzed using the thematic content analysis technique. Results showed that work specialization (?= 0.491, p=.000) had a statistically significant and positive influence on the development of employees at TKNB. Based on the findings, the study recommends that the management at TKNB should enhance work specialization by implementing job rotation programs and promoting a match between employees’ skills and their job.
Influence of church policies on the economic empowerment of the youth
Authors: Karanu Mercy , Koome Peter , Gesimba Paul Omato
Published: September 2020

Kenyan youths have been marginalized from mainstream economic activities since independence. This situation has had a negative impact such as slowed economic growth, a rise in crime and violence, and the spread of diseases. It is these issues that have prompted this study on the influence of church policies on the economic empowerment of youths with a specific focus on the PCEA Nyahururu Parish. The study was guided by the Positive Youth Development model. It employed the descriptive research design and targeted a population of 233respondents comprising of 220 youths and 13 leaders (2 congregation chairpersons, 1 clergy, 1 evangelist, 1 youth coordinator, and 8 youth leaders). From this population, a sample of 94respondentswas selected using the clustered random sampling method where the two congregations that make up the PCEA Nyahururu Parish formed the clusters. Quantitative data was collected from youths using structured questionnaires while qualitative data was collected from the church administrators using interview guides. Quantitative data were analyzed using descriptive statistics such as percentages and means as well as inferential statistics. Qualitative data were analyzed using the thematic content analysis technique and results reported using quotes. Findings revealed that there is a low level of economic empowerment among the youths at the PCEA Nyahururu parish. Church policies on single parenthood and divorce/ separation have a statistically significant and negative contribution towards youth economic empowerment. Church policies on the use of modern technologies have a positive and statistically significant relationship with youth economic empowerment. The study recommends that churches should re-examine its policies in single parenthood and divorce/ separation.
Longevity of the process of selling rice in bulk in municipal markets
Authors: Merchan Diana , Criollo Mónica , Arteaga Marina , Agila Mercy
Published: September 2020

Municipal markets began to be built more than 90 years ago in Ecuador, some have already been remodeled and there are also new buildings with modern designs but within them, the process of selling rice in bulk remains in this XXI century. The object of study of this work is the market "Las Manuelas" located in the province of Guayas in the canton of Duran. The method of selling bulk rice exposes this product to some types of food hazards, so the aim of this research is to determine the index of the criticality of the activities related to this long-lasting process that is currently being promoted as a process that does not pollute the environment. The observation technique was applied to make the food circulation diagram and the AMEF methodology was used to obtain the criticality index (CI) and according to the decision tree of the World Health Organization, the critical control points were established. Results obtained showed that the activity of storage and dispatch of bulk rice within the municipal market presented the highest ICs, under these parameters the importance of establishing preventive actions that could give a turn to this type of business.
The practice of job crafting and its impact on job outcomes
Authors: Karollah Banta , Monita Yuli , Vilzati Vilzati , Muhammad Muhammad , Ibrahim Mahdani
Published: September 2020

This study aims to investigate the effect of job crafting practices on job outcomes (work engagement and job satisfaction). This research was conducted on workers at Perseroan Terbatas (PT). Petra Arun Gas (PAG) with a working population of 180 people. Samples were taken as many as 123 people based on Krejcie and Morgan Sample Tables (in Sekaran & Bougie, 2009, pp. 254-255). The selection of sample members was carried out using the simple random sampling method. Primary data is obtained by distributing questionnaires to all samples. Data were analyzed using simple linear regression analysis tools with the help of SPSS. The results of the research data analysis show that job crafting has a significant effect on the two dependent constructs, namely work engagement and job satisfaction.
Examining stakeholder involvement in the evaluation process for program improvement
Authors: Okul Edwin Ochieng , Nyonje Raphael Ondeko
Published: September 2020

The results of an evaluation should be used for the envisioned goal and the evaluation process and/or outcomes should be used in practice and decision making. This article presents research whose objective was to establish the extent to which stakeholder involvement in evaluations impacts the utilization of evaluation findings for program improvement. Guided by the pragmatic paradigm and supported by the Utilization-Focused Evaluation Model and Knowledge Use Theory, the researchers assumed a descriptive and correlational design using mixed methods. The sample size for this study was 232 project staff from Non-Governmental Organizations (NGOs) in Kisumu Central Sub-County, Kenya. To analyze qualitative data, the open-ended responses from key informant interviews were recorded and coded appropriately for further analysis for themes through content analysis and comparative analysis. Frequencies and percentages were calculated to describe the basic characteristics of the quantitative data. To ensure the validity and reliability of the research instruments, pilot testing was conducted. Cronbach’s alpha at ? = 0.908 was attained as the reliability coefficient of the pre-test instruments. Tests of statistical assumptions were carried out before data analysis to avoid invalidation. A hypothesis was tested at the ? = .05 level of significance and was rejected. The findings demonstrate that there is a significant relationship between stakeholder involvement in evaluations and the utilization of evaluation results. This research, therefore, reinforces literature and helps to understand the ways in which stakeholder involvement in evaluations influences the utilization of evaluation results. It informs the evaluation field of study, fills gaps in the evaluation use literature, and contributes to the appreciation of factors that predict and enhance the utilization of evaluation results
Influence of income-generating activities on management effectiveness of charitable children institutions in Nakuru Town East Sub-County
Authors: Waweru John Anthony , Koome Peter , Omondi Alice Wairimu
Published: September 2020

This study investigates the influence of income-generating activities on the effective management of charitable children institutions (CCIs) with a particular focus on CCIs in Nakuru Town East Sub County, Kenya. The study was guided by the resource-based theory. The study adopted a mixed-method approach and deployed the descriptive research design to capture data from a target population of 45 respondents comprising of 39 CCI staff (both management and subordinate) and 6 key informants. A complete census was conducted on all the respondents and purposive sampling was utilized to identify key informants. Data from the CCI staff was collected using questionnaires while data from key informants was collected using discussion guides. A pilot study was conducted at Tumaini Bethany and Holy Family children in Nakuru Town West Sub-County to assess the validity and reliability of the instruments. Data were analyzed using the descriptive statistics with the help of the Statistical Package for Social Sciences software (SPSS) and the thematic content analysis technique. The findings from the study showed that income-generating activities had an influence on the effective management of CCIs. The study concluded that effective management of CCIs is shaped by the presence of income-generating activities in CCI, type of income-generating activities, and the amount of income generated by the activity in which the CCI is engaged. The study recommended that CCIs should develop income-generating activities in their institutional plans to mitigate shocks that occur when there is little funding from external partners.
Effect of talent management on service delivery in the hospitality industry
Authors: Wangechi Edward Mwangi , Koome Peter , Gesimba Paul
Published: September 2020

Talent management impacts on service delivery in the hospitality industry. The aim of the study was to assess the effect of learning and development on service delivery in the hospitality industry in Nyeri County, Kenya. The study employed a cross-sectional survey design to determine the relationship between the variables. The target population was 310 employees of three hotels who comprised of supervisors, room stewards, food and beverage managers, waiters, storekeepers, and chefs in three hospitality establishments in Nyeri County. The research used a stratified sampling technique to select 104 participants for the study.  The main instrument for data collection was a semi-structured questionnaire. The findings of the study revealed that learning and development have a significant and positive influence on service delivery. The study recommends that organizations should stress and develop robust learning and development interventions to mitigate performance-related challenges, realize the desired quality service delivery and stability, and gain a competitive edge. It is hoped and desired that this journal will lead to a supplementary examination of the bene?ts of this refocus on talent and management, including the development of useful de?nitions.
Examining the relationship between self-actualization and job performance via taking charge
Authors: Kumar Nilesh , Liu Zhiqiang , Hossain Md.Yahin
Published: September 2020

Based on Construal-level theory, this study hypothesized that self-actualization positively relates to employees’ taking charge, and self-actualization affects creative performance and normal performance through taking charge positively, but the effect is different. The authors selected a cross-sectional design to investigate interrelations amongst study variables at two different time points with the interval of one month, and surveyed 417 team members and 186 immediate team leaders in the banking sector in Pakistan. The authors used individual-level data to evaluate the validity and test the proposed relationships by using Mplus. They revealed that self-actualization affects taking charge positively, and taking charge mediated the relationship with the difference in effect e.g. taking charge has high effect on creative performance in comparison to normal performance. The outcomes carry important implications aimed at increasing high-level self-actualization that results in taking charge, and so on leads to creative and normal performance.
Investments and portfolio structure of private pension and insurance companies in North Macedonia
Authors: Dervishi Bulent
Published: September 2020

The financial market in general is where supply and demand for funds are met. In other words, funds saved in the financial market are directed to investments in order to contribute to the economy. In the Macedonian financial market, the banking sector is really dominant but also pension funds and insurance funds have an active role. This research will be studied the distribution of pension funds’ portfolios in the North Macedonian financial market. The global financial crisis in 2008 negatively affected the economies and financial markets of many countries, including the USA and Europe, and the effects of the crisis continued until 2013. This negatively affected the confidence in the financial markets, and the current surplus of funds was directed towards low-risk but fixed or low-yield financial instruments. As of 31.12.2018, fund accumulation in private pension funds amounted to 1.04 billion euros, corresponding to approximately 10 percent of GDP. The total premium production of insurance companies is around 157 million euros, while the GDP ratio of premium production is around 1.5 percent. Funds collected in both sectors are generally used in treasury bills, bank deposits, and stocks traded on the Macedonia Stock Exchange and foreign financial markets.