bluuebunny/crossref_metadata_2025 huggingface dataset:
Mi gran compañera. La familia multiespecie y las potencias del afectar
Authors: Varela Trejo David A.
Published: January 2024

Este artículo explora, a partir de un relato de vida, la relación de afinidad, familiaridad y parentesco interespecie entre Mauro, un humano de la tercera edad con una enfermedad neurodegenerativa (Parkinson) y Chabela, una perra racializada como schnauzer miniatura. En la primera parte discuto el marco teórico-político desde el que se enuncia este trabajo. En un segundo momento, introduzco el relato de Mauro y Chabela entendido como un evento interespecie de cuidado, compañía y amor. Por último, realizó un ejercicio de interlocución con Chabela para desvelar su potencia para afectar, la importancia que adquieren los cuerpos y transformar radicalmente las disposiciones afectivas o el orden amoroso del humano con quien convive, lo cual permite pensar futuros multiespecie en clave contra-especista y especular con lo que llamó xeno-familias
Safety and feasibility of preoperative simultaneous portal vein embolization and biliary drainage in hilar cholangiocarcinoma prior to hepatectomy
Authors: Soliman Mohamed M. , Chevallier Olivier , Velayati Sara , Zhao Ken , Marinelli Brett , Ridouani Fourat , Karimi Anita , Covey Anne , Erinjeri Joseph P. , Schattner Mark , Harding James J. , Abou-Alfa Ghassan K. , Wei Alice C. , Soares Kevin C. , Jarnagin William , Yarmohammadi Hooman
Published: January 2024

Purpose: Evaluate safety and feasibility of simultaneous biliary drainage (BD) and portal vein embolization (PVE) prior to hepatectomy in hilar cholangiocarcinoma (HCCA) patients. Methods: From January 2010 to June 2022, patients with potentially surgically resectable HCCA who underwent preoperative PVE and BD were analyzed. Type of initial BD, time interval between BD and PVE, changes in future liver remnant (FLR), time interval between BD, PVE and resection, and complications were recorded. Patients were divided into 3 groups based on the BD-PVE interval: Group A: simultaneous BD and PVE or within 7 days (d), n = 6; Group B: d ≥ 7 to ≤ 30, n = 7; Group C: d > 30, n = 14). Primary endpoints were post-PVE complications, FLR change, and resection rate. Secondary endpoints were Clavien-Dindo ≥ 3, Grade B/C Post Hepatectomy Liver Failure (PHLF) and 90 days mortality rate. Results: A total of 27 patients (mean age = 64.4 +/- 11.2 years) underwent both BD and PVE prior to hepatectomy. Mean degree of hypertrophy at 4-6 weeks post-PVE was 10.4 +/- 3.7% with no significant difference between the 3 groups (p > 0.05). Resection was 67% in Group A, and 57% and 36% in groups B and C respectively (p < 0.05). Time to surgery was 38.5 +/- 12 days in Group A, and 60 and 147 days in groups B and C respectively (p = 0.002). No major post PVE SIR complication was reported in group A. Overall rate of Grade III/IV Clavien-Dindo complication was 61.5% with no difference among the three groups (50%, 75%, and 60%; groups A, B and C, respectively). Overall PHLF Grade B/C was reported in 46.2% of patients. No patients in Group A demonstrated Grade B/C PHLF. Conclusion: Simultaneous BD and PVE is safe and reduces the time to surgery, which may help contribute to a higher rate of surgical resection.
La innovación y la sustitución energética como medidas de corrección medioambiental en países de la OCDE
Authors: Balsalobre Lorente Daniel , Álvarez-Herránz Agustín , Baños Torres José
Published: January 2024

El presente estudio aborda la corrección producida en el nivel de emisiones de gases efecto invernadero (GEI)  a través del papel que, junto al crecimiento económico, juegan tanto la innovación en tecnología energética como el patrón de consumo energético por fuentes de origen renovable; donde además se incorpora al análisis, a través de una variable moderadora, el impacto que el nivel de renta ejerce sobre la sustitución energética en dicho proceso de corrección medioambiental.Para tal fin, se ha utilizado el argumento metodológico que propone la Curva de Kuznets Ambiental -CKA-, a través del diseño de un modelo econométrico con datos de panel de efectos fijos para 24 países de la OCDE en el periodo 1992-2010. Con las limitaciones de alcance propias de los datos utilizados, hemos obtenido evidencia de que el esfuerzo de las administraciones en innovación y sustitución energética se asocia con la reducción en el nivel de emisiones GEI.
PRESENTACIÓN
Authors: Montero José María , Booth Philip
Published: January 2024

Más de un siglo ha pasado (en concreto, 107 años) desde la creación por Antonio Maura del Instituto Nacional de Previsión español, promulgado por Alfonso XIII por la Ley de 27 de Febrero de 1908, que constituyó la primera institución oficial de nuestro país encargada de las cuestiones relativas a la Seguridad Social y la Asistencia Sanitaria. El régimen legal de retiros obreros (por tanto sin carácter universal, incluso dentro de la propia clase obrera) se estableció bajo el sistema de libertad subsidiada, quedando relegado el papel del Estado a las cuestiones de regulación y a una determinada aportación. Y aunque hoy en día a algunos les pueda resultar sorprendente, se trataba de un régimen, aunque no totalmente puro, de capitalización, que pasó por una serie de vicisitudes derivadas de las condiciones en las que se creó, hasta que mediante la Ley de 1 de Septiembre de 1939 fue sustituido por, en términos de la propia ley, "el pago de pensiones fijas en concepto de subsidio de vejez".
Spanish Minimum Pensions after the 2013 Pension Reform
Authors: Díaz-Giménez Javier , Díaz-Saavedra Julián
Published: January 2024

In this article we explore the consequences of exempting minimum pensions from the Pension Revaluation Index (PRI) introduced by the 2013 reform of the Spanish pension system and making their real value a constant share of per capita output instead. We find that this change essentially implies trading-off higher minimum pensions against a lower PRI -which reduces the real value of all other pensions- and against the higher consumption tax rates that are needed to finance them. When faced with these trade-offs, the optimal responses of the households in our model economy are to work shorter hours, to retire earlier, and to save less. They also consume less to avoid paying some of the higher consumption taxes. All this implies that preserving the real value of minimum pensions makes the growth rates of output smaller. We also find that this change compresses the range of pensions, and that as many as 48 percent of the retirees in our model economy collect the minimum pension in 2050. This share is 28 percentage points higher than the share of 2010. It also implies that pensions are more equally distributed because the bottom tail of the pension distribution collects a larger share of the total. Finally, we find that preserving the real value of minimum pensions brings about large welfare gains.
Appraising the Financial Sustainability of a Pension System with Signal Processing
Authors: Rostan Pierre , Belhachemi Rachid , Rostan Alexandra
Published: January 2024

One key issue of the Spanish pension system is its financial sustainability in regard to slumping fertility rate and rising longevity of the Spanish population. The paper presents a versatile and robust model that may help pension managers gain insight into the future Spanish pyramid of ages, from which they will appraise cash inflows and outflows of the pension system. The model forecasts ninety years of the Spanish population for each cohort of the pyramid of ages. Borrowed from the signal processing discipline, the model relies on the Burg method which fits a pth order autoregressive (AR) model to the input signal by minimizing (least squares) the forward and backward prediction errors while constrai-ning the AR parameters to satisfy the Levinson-Durbin recursión, then uses  an infinite impulse response prediction error filter. Results add better perspective and insight to the Spanish population projection forecasted by the United Nations Population Division.
The Impact of pPb W/Z LHC Data on nCTEQ15 Parton Distribution Functions With an Emphasis on Refitting the nCTEQ15 nPDF Set
Authors:   ,   Southern Methodist University, Godat Eric
Published: January 2024

As the LHC experiments increase their statistics and reduce their systematics, it is in- creasingly important to reduce the theoretical uncertainties so we can perform precision com- parisons. The parton distribution functions (PDFs) which describe the hadronic structure of protons and nuclei are the critical link between the experimental data and the proposed theoretical models; hence, a better understanding of the PDFs is essential for improved pre- dictions. Nuclear PDFs, in particular, have proven valuable in this regard, especially for flavor differentiation. I introduce ”nCTEQ+LHC,” the first PDF set fit using the nCTEQ formalism to include data from the LHC. This PDF set also represents the first results of the new (C++ based) ”nCTEQ++” fitting code. To incorporate many new LHC processes into nCTEQ++, I developed and tested a novel way of uniting various theory tools in a modular framework to enable fast PDF fitting of complex higher-order theory calculations using modern grid techniques. This combination of tools provides a foundation for a wide variety of future analysis involving both proton and nuclear data.
Adequabilidade do conhecimento e atitude de profissionais na avaliação das incapacidades hansênicas
Authors: Santana Emanuelle Malzac Freire de , Brito Karen Krystine Gonçalves de , Antas Ester Missias Villaverde , Nóbrega Matheus de Medeiros , Carvalho Paula Soares de , Pacheco Flávia Cristina dos Santos , Leadebal Oriana Deyze Correia Paiva , Nogueira Jordana de Almeida , Soares Maria Júlia Guimarães Oliveira , Oliveira Simone Helena dos Santos
Published: January 2024

Objetivo: Comparar a adequabilidade do conhecimento e da atitude de profissionais da atenção básica na avaliação do grau de incapacidade física na hanseníase antes e após intervenção educativa e associá-la à vivências em capacitações e na prática assistencial. Métodos: Estudo de intervenção norteado pela Teoria da Aprendizagem Significativa envolvendo 122 profissionais da atenção básica de João Pessoa, Paraíba. Utilizou-se instrumento próprio de conteúdo validado para coletar os dados intitulado “Conhecimento e Atitude sobre a Avaliação do Grau de Incapacidade Física na Hanseníase”, composto por 32 questões, subdivididas em dois constructos: Conhecimento, que englobou as dimensões Avaliação Neurológica Simplificada (ANS) (12 questões) e Grau de Incapacidade Física (GIF) (12 questões); e Atitude (8 questões). Foi aplicada estatística descritiva e inferencial pelo software estatístico R. Resultados: Antes da intervenção as médias de acertos do conhecimento e da atitude estiveram abaixo de 50%, constatando-se diferença estatisticamente significativa (p<0,001) entre os conhecimentos e as atitudes dos profissionais após a intervenção, posto aumento superior a 90%, independente de participação prévia em capacitações ou de vivências na assistência. Conclusão: Ocorreu adequabilidade do conhecimento e da atitude comparada ao momento prévio, atestando que ocorreu aprendizagem significativa entre os profissionais.
Reactivation of retinopathy of prematurity after intravitreal aflibercept treatment depends on gestational age
Authors:   N.I. Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russian Federation, Sidorenko E.I. ,   N.I. Pirogov Russian National Research Medical Universityof the Ministry of Health of the Russian Federation, Brunch Children’s Clinical Hospital, Moscow, Russian Federation, Sidorenko E.E. ,   N.I. Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russian Federation,   V.F. Voino-Yasenetsky Scientific and Practical Center for Specialized Medical Care in Children of Department of Health of Moscow, Moscow, Russian Federation, Obrubov S.A. ,   N.I. Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russian Federation,   N.I. Pirogov Russian National Research Medical Universityof the Ministry of Health of the Russian Federation, Brunch Children’s Clinical Hospital, Moscow, Russian Federation, Le H.T. ,   N.I. Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russian Federation
Published: January 2024

Material and methods. This study was conducted at the V.F. Voino-Yasenetsky Scientific and Practical Center for Specialized Medical Care in Children from September 2021 to February 2023. The study included 122 premature infants (244 eyes) with retinopathy of prematurity who received intravitreal administration of aflibercept. All patients were divided into 3 groups depending on gestational age, including a group of patients with a gestational age of less than 27 weeks (70 eyes), a group of patients with a gestational age of 27 to 29 weeks (106 eyes) and a group of patients with a gestational age of from 29 weeks (68 eyes). All patients were monitored for reactivation of retinopathy of prematurity after intravitreal aflibercept injection. Results. The overall relapse rate after treatment was 37/244 eyes (15.16%); The reactivation rate of the gestational age >29 weeks group was 5.88% of the middle gestational age group – 9.43% and the low gestational age group (<27 weeks) – 32.86% respectively. The reactivation time in the three groups of patients was 10.75±5.03 weeks for the low gestational age group, 7.40±4.04 weeks for the middle gestational age group, and 15,00±11,31 weeks for the high gestational age group. Conclusion. Intravitreal injection of aflibercept is an effective treatment for ROP. The younger the gestational age, the more often and faster reactivation of ROP occurs after injections of angiogenesis inhibitors. Key words: recurrence, reactivation, retinopathy of prematurity, risk factor, gestational age, intravitreal injection, aflibercept, vascular endothelial growth factor, angiogenesis inhibitors
Retinal hemorrhages in newborns. Clinical features and risk factors
Authors:   St. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, St. Petersburg, Russian, Kireeva V.A. , Brzheskiy V.V. ,   St. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, St. Petersburg, Russian
Published: January 2024

Material and methods. The study included newborns born at the Perinatal Center of St. Petersburg State Pediatric Medical University in the period from July 2021 to October 2022. Anamnestic and other risk factors for the development of retinal hemorrhages were assessed in newborns with and without retinal hemorrhages (RH). Depending on the severity of RH (according to the results of the examination on the RetCam retinal camera), the newborns were divided into groups in which the bilaterality of the RH was assessed, localization in the layers and area of the retina, with an emphasis on the macular region and the optic disk. Results. Of the 75 newborns, 16 had birth-related RH (23.1%). Normal spontaneous vaginal delivery showed the highest association with RH (odds ratio, 5.515; 95% confidence interval, 1.15–26.46, p<0.001). Hemorrhages were more often bilateral (68.8%), intraretinal (87.5%) and localized in the central zone of the retina (81.3%). At the same time, severe RH were more often located in zones I and II, in each newborn they affected the optic nerve or macula, in 6.3% of cases they spread to the vitreous body, and in 25% they were accompanied by Roth’s spots. Conclusion. RH occur in 21.3% of full-term newborns and are largely associated with normal delivery. The main characteristics of hemorrhages in newborns differ notably depending on their severity. Severe retinal hemorrhages in newborns may have negative consequences for the development of visual functions at an older age, which requires further long-term studies. This study confirmed that the digital wide-angle retinal camera is an effective method for examining a large number of newborns with RH. Key words: newborn, retinal hemorrhages, vitreous hemorrhages, Roth’s spots
EFEKIVITAS MUSYAWARAH PERENCANAAN PEMBANGUNAN (MUSRENBANG) DESA DI DESA PULAU KOMANG KECAMATAN SENTAJO RAYA KABUPATEN KUANTAN SINGINGI TAHUN 2016
Authors: Rivaldi Andesko , Yusa Ahmad Tarmizi
Published: January 2024

This research was conducted in Pulau Komang Village, Sentajo Raya District, Kuantan Singingi Regency. The purpose of this study was to determine the effectiveness of the Village Development Planning Meeting (Musrenbang) in Pulau Komang Village, Sentajo Raya District, Kuantan Singingi Regency in 2016. The usefulness of this study is also expected to be an input for Pulau Komang Village regarding the implementation of Village Development Planning Consultations, and also expected to be useful to increase knowledge and can be a reference for further research with the same subject matter. With the aim of knowing and explaining the Effectiveness of Village Development Planning Consultation in Pulau Komang Village. In line with the purpose of this study, the population and sample in this study were the Village Heads of Pulau Komang, the Village Commands of Pulau Komang amounted to 3 people, the Village Consultative Body of Pulau Komang as many as 3 people and the Community Shop of Village Pulau Komang as many as 5 people. The sampling technique used is the Slovin formula cited by Danang Sunyoto (20013; 16), and the theory I use is a theory from Permendagri Number 66 of 2007, with indicators set as many as 3 indicators. After all data were analyzed with quantitative and qualitative research, the results of research on the effectiveness of Village Development Planning (Musrenbang) in Pulau Komang Village, Sentajo Raya District, Kuantan Singingi Regency in 2016 were included in the category of "Effective Enough"..
IMPLEMENTASI KEBIJAKAN ELEKTRONIK KARTU TANDA PENDUDUK (E-KTP) DI KABUPATEN KUANTAN SINGINGI
Authors: Zulkifli Zulkifli , Wedayanti Made Devi , Arjuna Nita
Published: January 2024

The implementation of the national electronic program for current residents' cards and future time frames has always been an actual phenomenon to be discussed and researched. The same phenomenon in linear terms certainly reaches throughout the regency and city areas in Indonesia, including in KuantanSingingi Regency. The purpose of this study was to find out and analyze the conditions of the objective implementation of the resident card electronic policy in KuantanSingingi Regency. The reference analysis is an indicator of the implementation of public policy theory - communication, resources, disposition, bureaucratic structure. The research method used descriptive survey, data analysis instruments using frequency tables. Sunber frequency table data from Likert scale development. Likert scale is used as a reference to categorize the opinions or attitudes of respondents. While the main instrument for collecting data is a semi-guided interview. The results of the study, the implementation of the electronic policy of identity cards in KuantanSingingi District has been well run by the implementors
Penerapan Prinsip Prinsip Pelayanan Publik Di Bidang Pelayanan Pendaftaran Penduduk Dan Catatan Sipil Kantor Dinas Kependudukan Dan Catatan Sipil Kota Pekanbaru
Authors: Hamim Sufian , Vianda Lolita , Pitaloka Sella
Published: January 2024

The purpose of the study was to analyze and explain the application of the principles of public service in the Field of Population Registration and Civil Registration Services Office of the Population and Civil Registry Office of the City of Pekanbaru. This research uses quantitative and qualitative approaches to strengthen one another. A quantitative approach to descriptive statistical analysis, with survey methods. In survey research, information was collected from 42 respondents using a questionnaire and the collection of relevant secondary data. The qualitative approach was carried out by interviewing 10 informants and observations involved to complement the quantitative approach. Overall implementation of the principles of public service in the Department of Population and Civil Registry Pekanbaru City is in the category of implemented or 36%, quite implemented or 45% and less implemented or 19%. Civil Registry Pekanbaru City, only one indicator of the principle of public service security that has been implemented well or 56%. This means that the management process feels safe, there are security guards, no fighting incidents have occurred, all applicant communities can take shelter from rain or heat because the office is quite large, it's just not comfortable because the service and waiting rooms feel cramped and noisy, while the products are legal and legal. Only one indicator of the principle of public service convenience is less well implemented or 39%. This means that public services at the Department of Population and Civil Registry of Pekanbaru City are lacking in comfort, the community feels that the service process is lacking in order, many people stand unable to sit, a bit chaotic, noisy noise and hot air temperature; office environment Not comfortable there is no green park and the office waiting room is narrow and not clean; The parking lot is narrow and cluttered, mostly using public roads; the toilets are less clean, the number of users is small, there are no prayer rooms for prayer rooms. The other eight principles of public service have been implemented quite well or 45%, namely: simplicity, clarity, time certainty, accuracy, responsibility, infrastructure, ease of access, and discipline. The indicator that is not well implemented is the principle of comfort. Therefore, in the future Pekanbaru City Population and Civil Registry Office should improve comfort in public services.
“Satu Nagari Satu Event” Sebuah Upaya Untuk Kemajuan Kabupaten Tanah Datar
Authors: Feby Hidayat  , Frinaldi Aldri , Magriasti Lince
Published: January 2024

The authority given to local governments by the central government to manage regional affairs for the benefit of the people is known as decentralization. The Tanah Datar Regency Government makes a policy through the “One Village One Event” program. The purpose of this study was to determine the benefits and inhibiting factors in implementing “One Village One Event” using a qualitative approach. By describing the implementation of “One Village One Event” activities, this type of research is descriptive in nature. In this study, interview techniques, documentation, literature reviews in journals and online media, and documentation were used to collect data. The results of this study indicate that the benefits of ”One Village One Event” are Preserving Culture, Exploring Local Potential, Increasing Tourism and Increasing the Community's Economy. The implementation went smoothly and without any significant obstacles.
Passing the Torch: How Parental Privacy Concerns Affect Adolescent Self-Disclosure on Social Networking Sites
Authors:   University of Texas at Arlington, Wang Jingguo , Dong Meichen ,   Lamar University, Yang Zhiyong ,   Miami University, Li Yuan ,   University of Tennessee
Published: January 2024

Drawing upon the literatures in information privacy, developmental psychology, and family science, this research investigates how parental online privacy concerns can be passed on to adolescents and affect their self-disclosure on social networking sites. We propose that parental privacy concerns decrease adolescents’ self-disclosure both directly (i.e., compliance) and indirectly through adolescents’ privacy concerns (i.e., internalization) and that such effects are moderated by parent-child privacy dissonance, parental internet evaluative mediation, and adolescents’ gender. To test the research model, we collected matched parent-child data from 726 families in China. The results show the indirect effect of parental privacy concerns on adolescents’ self-disclosure via their influence on adolescents’ privacy concerns. In addition, parent-child privacy dissonance weakens the effect of adolescents’ privacy concerns on self-disclosure. The extent to which parents employ internet evaluative mediation to guide adolescents’ online activities reinforces the effect of parental privacy concerns on adolescents’ privacy concerns. Statistical analyses further revealed that the mediating effect of adolescents’ privacy concerns is weakened by parent-child privacy dissonance but strengthened by internet evaluative mediation. We also found that parental privacy concerns affect sons and daughters through different paths, especially when parents employ high internet evaluative mediation. Under high internet evaluative mediation, parental privacy concerns affect sons’ self-disclosure primarily through an indirect path (via sons’ privacy concerns), but influence daughters’ self-disclosure both directly and indirectly via daughters’ privacy concerns. We conclude by discussing theoretical contributions and practical implications.
Reviewing from a Distance: Uncovering Asymmetric Moderations of Spatial and Temporal Distance between Sentiment Negativity and Rating
Authors:   Paderborn University, Neumann Jürgen , Gutt Dominik ,   Erasmus University Rotterdam, Kundisch Dennis ,   Paderborn University
Published: January 2024

Drawing on construal level theory, prior literature has found a positivity bias in online ratings when consumers evaluate an experience from a psychological distance, whether spatial or temporal. Self-distancing theory posits that psychological distance enables individuals to reflect on psychologically distant negative experiences more genuinely, in a less biased way. This raises the question of whether the positivity bias in ratings due to psychological distance persists for negative experiences. To address this question, we collected data from a large review platform that enables the identification of reviewers’ spatial and temporal distance. The negativity of an experience was operationalized via review text sentiment. We introduced spatial and temporal distance as moderators between sentiment negativity and ratings and found a negative moderation by spatial distance and a positive moderation by temporal distance. Our findings indicate that the relationship between sentiment negativity and rating grows stronger under spatial distance and gets weaker under temporal distance. Text mining confirmed self-distancing as the driver behind the spatial moderation and construal levels as the driver behind the temporal moderation. We attribute the asymmetric moderations to differences in the tangibility of spatial distance (more tangible) and temporal distance (less tangible). These results improve our understanding of reviewing behavior and can help platforms de-bias ratings.
Comparing Platform Owners’ Early and Late Entry into Complementary Markets
Authors:   University of Sussex, Shi Runyu , Aaltonen Aleksi ,   Temple University, Henfridsson Ola ,   University of Miami, Gopal Ram ,   University of Warwick
Published: January 2024

Research on platform owners’ entry into complementary markets points in divergent directions. One strand of the literature reports a squeeze on post-entry complementor profits due to increased competition, while another observes positive effects as increased customer attention and innovation benefit the complementary market as a whole. In this research note, we seek to transcend these conflicting views by comparing the effects of the early and late timing of platform owners’ entry. We apply a difference-in-differences design to explore the drivers and effects of the timing of platform owners’ entry using data from three entries that Amazon made into its Alexa voice assistant’s complementary markets. Our findings suggest that early entry is driven by the motivation to boost the overall value creation of the complementary market, whereas late entry is driven by the motivation to capture value already created in a key complementary market. Importantly, our findings suggest that early entry, in contrast to late entry, creates substantial consumer attention that benefits complementors offering specialized functionality. In addition, the findings also suggest that complementors with more experience are more likely to benefit from the increased consumer attention. We contribute to platform research by showing that the timing of the platform owner’s entry matters in a way that can potentially reconcile conflicting findings regarding the consequences of platform owners’ entry into complementary markets.
Water-Soluble Poly(phenylene ethynylene)s that Contain Phosphonium Pendant Groups
Authors: Barboza-Ramos Isaí , Gobeze Habtom , Wherrit Daniel , Schanze Kirk
Published: January 2024

Expanding the functionality of conjugated polyelectrolytes (CPEs) is important for polymer- mediated biosensing applications. The current study reports the design and synthesis of a novel class of water-soluble poly(phenylene ethynylene) (PPE)-based CPEs, featuring cationic trimethyl phosphonium (-PMe3+) moieties as pendant groups. A series of four CPEs were prepared which vary in the number of -PMe3+ groups and the length of the side-chains linking the phosphonium groups to the PPE backbone (3- or 6-carbon linkers). The polymers’ molecular weights (MW) were estimated by diffusion-ordered NMR spectroscopy (DOSY) in methanol relative to poly(ethylene glycol) standards, and MW values ranging from 10 – 30 kD were recovered. The photophysical properties of the new CPEs were assessed by steady state and time-resolved fluorescence spectroscopy analysis, using polymer solutions in water and methanol. Interesting relationships were observed between the optical properties and the structural variations of the new CPEs. Namely, the fluorescence reveals that the CPEs aggregate in water, with the degree of aggregation increasing with fewer -PMe3+ groups, and longer side-chains. The fluorescence quantum yields of the CPEs in methanol are high, with one exhibiting > 90% yield. Transient absorption spectroscopy on timescales from picoseconds to microseconds probes the excited state structure and dynamics of the CPEs in water and methanol. The singlet exciton state decays more rapidly in water due to non-radiative decay promoted by aggregation states. Excitation of the polymers produces triplet excitons and studies using singlet oxygen (1O2) phosphorescence and an anthracene-based probe confirm that 1O2 is produced by sensitization. Addition of pyrophosphate (PPi) to the phosphonium CPEs in methanol leads to fluorescence quenching; the mechanism of quenching is attributed to aggregation induced quenching.
Pre-analytical (mis)handling of plasma investigated by 1H-NMR metabolomics
Authors: Malmodin Daniel , Bay Nord Anders , Zafar Huma , Paulson Linda , Karlsson Göran , Torinsson Naluai Åsa
Published: January 2024

The pre-analytical handling of plasma, how it is drawn, processed, and stored, influences its composition. Samples in e.g. biobanks often lack this information and consequently important information about their quality. Especially metabolite concentrations are affected by pre-analytical handling making conclusions from metabolomics studies particularly sensitive to misinterpretations. The perturbed metabolite profile, however, also offers an attractive choice for assessing the pre-analytical history from the measured data. Here we show that it is possible using Orthogonal Projections to Latent Structures Discriminative Analysis to divide plasma NMR data into a multivariate 'original sample space' suitable for further less biased metabolomics analysis and an orthogonal 'pre-analytical handling space' describing the changes occurring from pre-analytical mishandling. Apart from confirming established pre-analytical effects on glucose metabolization and the consequent increase in e.g. lactate and pyruvate, the sample preparation protocol involved methanol precipitation which allowed the observation of reversible changes in short-chain fatty acid concentrations as a function of temperature.
Transition State Theory within Constrained Nuclear-Electronic Orbital Framework: Accurate Hydrogen Atom Transfer Reaction Rates with Direct Incorporation of Quantum Nuclear Delocalization Effects
Authors: Chen Zehua , Yang Yang
Published: January 2024

Hydrogen atom transfer is crucial in a myriad of chemical and biological processes, yet the accurate and efficient descriptions of hydrogen atom transfer reactions remain highly challenging due to the significant nuclear quantum effects of hydrogen nuclei. In this paper, we integrate traditional transition state theory (TST) with the recently developed constrained nuclear-electronic orbital density functional theory (CNEO-DFT) and predict the reaction rate constants for two prototypical gas-phase hydrogen atom transfer reactions. We find that with a good description of nuclear quantum effects, especially the quantum delocalization effects, CNEO-DFT in combination with TST can accurately predict the hydrogen transfer reaction rates. Notably, this approach maintains computational efficiency comparable to conventional DFT-based TST but achieves accuracy comparable to more intricate DFT-based variational TST with tunneling corrections. Hence, CNEO-DFT combined with TST is a promising tool for future investigations of hydrogen atom transfer reactions within more complex chemical and biological systems.
HCN Dimers to HCN Tetramers: Computational Exploration of Binary Reactions
Authors: Panda Sunanda , Roy Saikat , Khatun Maya , Anoop Anakuthil
Published: January 2024

This study explores the self and cross-dimerization of HCN and HNC dimers, key elements in prebiotic chemistry, to explore potential phenomena crucial to the early stages of life on Earth, Titan, and other extraterrestrial environments. We utilise computational analysis to reveal various reaction products, predominantly featuring imine, nitrile, amine, and iminoamine functional groups, along with N-heterocycles like aziridines, azetenes, and triazole. Transition state search methods illuminate the mechanistic details of these reactions. Notably, we identify biomarkers such as a func- tional isomer of DAMN (D95) and imidazole derivatives (D45, D76, D79), which are potential precursors to nucleobases such as adenine, and polyimines that may serve as precursors to DNA and RNA helical structures. This study enhances our under- standing of the complex chemical pathways that may have contributed to the genesis of life’s foundational molecules in various cosmic settings.
Antioxidant and Antibacterial Activity of Endophytic Fungi Isolated from Fruit of Sungkai (Peronema canescens)
Authors: Oktiansyah Rian , Widjajanti Hary , Setiawan Arum , Elfita Elfita
Published: January 2024

Peronema canescens, often known as sungkai, is widely used and can be found all around Indonesia. The public believes that the leaves may reduce fever and strengthen the immune system. However, the effectiveness of sungkai fruit has not been thoroughly investigated. In this research, we looked at endophytic fungus extracts from sungkai fruit’s that have antioxidant and antibacterial properties. The study’s results will serve as the foundation for further investigation into the development of potential natural chemicals with antioxidant and antibacterial properties. Morphologically, the endophytic fungi isolated from sungkai fruit were identified. The antioxidant and antibacterial properties of endophytic fungal extracts were studied using the DPPH technique and the paper disk diffusion method. By employing molecular identification and column chromatography to separate the active compounds, the most likely endophytic fungal isolates were found based on the results of the bioactivity tests. Using 1D NMR spectroscopic methods, the chemical’s structure was determined, and the results were compared to NMR data for the same compound published in the literature. Fruit of sungkai had 8 strains of endophytic fungus (RBH1-RBH8). Strong antibacterial and very strong antioxidant activity were shown by the RBH5 isolate (IC50 < 20 μg/mL). Pythium periplocum was determined to be the RBH5 isolate based on molecular testing. Pure chemical compound extracted from RBH5 isolates shown highly potent and potent antibacterial and antioxidant effects. The chemical compound was identified by spectroscopy as 3-hydroxy-4(hydroxy(4-hydroxyphenyl)methyl)-γ-butyrolactone. The results of this study serve as the foundation for developing compounds as pharmaceutical raw materials via further research phases.
Carbon Dots-based Antifungal Coating Film Against Pathogens Colletotrichum sp. for Active Coating Application of Mango
Authors: Safitri Idayu , Sugiarti Sri , Darmawan Noviyan
Published: January 2024

Mangos are one of horticultural products that are leading the Indonesian agricultural industry. Simple post-harvest handling leads to high damage. The most common causes is anthracnose disease caused by Colletotrichum sp. Therefore, it’s necessary to modify the existing methods in postharvest handling such as coating. Adding active agents such as carbon dot (CD) in coating material to prevent anthracnose from growing and shorten the shelf life. This study aims to investigate the applicability and antifungal properties of CD as a composite coating. CDs were synthesized using chitosan as the carbon source in a one-pot hydrothermal technique. The CDs have blue-emitting luminescence caused by the functional group at the surface of CD. The CDs were used to prepare chitosan/pectin (Chi/Pec)-based composite coatings. The addition of CDs increased the viscosity and density of composites, increased the blue-emitting luminescence, and showed potential antioxidant activity. The CDs and composite coatings exhibited high antifungal activity against Colletotrichum sp. by agar well diffusion method and were classified as very strong antifungal agents. The chitosan/pectin/CDs-coating effectively reduced the growth of black spots on the surface of mangos and increased the fruit shelf life of the fruit by 24 days. The CDs are evidently safe, affordable, and value-added nanomaterials that can be used to prepare active packaging applications.
Optimization and Characterization of Liquid Smoke Produced by Terminalia catappa Wood Pyrolysis and its In Vitro Antifungal Activity
Authors: Oramahi Hasan Ashari , Maurisa Tirsa , Nurhaida Nurhaida , Darwati Herlina , Rifanjani Slamet
Published: January 2024

This research utilized response surface methodology (RSM) to explore how the yield of liquid smoke obtained from ketapang wood (Terminalia catappa) is influenced by the size of wood particles and the temperature of pyrolysis. Gas chromatography-mass spectrometry (GC-MS) was used to characterize the liquid smoke. To assess liquid smoke’s antifungal effects, a petri dish bioassay was conducted using 1.0-4.0% (v/v) concentrations against Schizophyllum commune. RSM was applied to optimize vinegar from T. catappa by varying the wood particle size and the pyrolysis temperature. The optimal yield, 24.67%, was obtained with a 3.22 mm particle size and a 425°C pyrolysis temperature. The liquid smoke produced at 400-450°C completely inhibited of S. commune growth at 2.0-4.0%. The primary components of the liquid smoke at 400°C were 2-methoxy- phenol (24.85%), creosol (8.39%), 4-ethyl-2-methoxy- phenol (7.21%), 2-5-methyl-furancarboxaldehyde (4.55%), and 4-ethyl-2-methoxy-phenol (3.74%). The primary components at 425°C were 2-methoxy-phenol (25.60%), creosol (15.15%), 5-methyl-2 furancarboxaldehyde (12.75%), and 2,6-dimethoxy-phenol (9.31%). At 450°C, the main components were 2-methoxy-phenol (25.26%), 4-ethyl-2-methoxy-phenol (8.46%), creosol (8.40%), 5-methyl-2-furancarboxaldehyde (4.02%), and 4-ethyl-2-methoxy-phenol (3.98%).
Palm Oil Fuel Ash and Fly Ash for a Partial Replacement of Cement in High-Quality, Environmentally Friendly Mortar as a Solution to Industrial Waste
Authors: Siregar Shinta Marito , Humaidi Syahrul , Bukit Nurdin , Frida Erna
Published: January 2024

This study explores the effects of incorporating palm oil fuel ash (POFA) and fly ash (FA) as partial cement substitutes on the mechanical properties and characteristics of high-quality mortar, specifically Engineered Cementitious Composites (ECC). ECC mortar was fabricated by milling POFA waste and FA through a top-down method utilizing a ball mill. The resulting material was subjected to tests for slump flow, water absorption, compressive strength, and characterized through XRF, FTIR, SEM/EDX, and XRD analyses. FTIR analysis verified the existence of Si-O and Al-O groups within the composite made of POFA-FA ECC. XRF analysis of FA and POFA showed cementitious properties, with SiO2+Al2O3+Fe2O3 exceeding 50% and CaO surpassing 10%. SEM and XRD results indicated minimal cavity formation, suggesting a high compressive strength in the mortar. Particle size distribution analysis revealed prevalent particles in the 1.5×10−1 to 2.0×10−1 μm range. The compressive strength test after 28 days, incorporating 15% FA and 10% POFA, yielded the highest strength at 59.30 MPa. The water absorption values ranged from 1.25% to 2.67%, indicating that POFA-FA assists in the cement hydration process and also serves as a filler. As a result, the material’s density is very high, leading to fewer voids formed, thus reducing the trapped water, which significantly affects the mortar’s strength.
Forest Fire Detection System for Preventing Flora & Fauna from Fire Using Computer Vision
Authors:   Department of Information Technology, Greater Noida Institute  Of Technology (Engineering Institute) Greater Noida, India, Gupta Dr.Pankaj , Singhal Prof.Vikas ,   Department - Information Technology,Greater Noida Institute of Technology (Engineering Institute) Gautam Buddh Nagar, India, Dubey Dr.Shivani ,   Department - Information Technology Greater Noida Institute of Technology (Engineering Institute) Gautam Buddh Nagar, India, Sahu Dr.Ajay Kumar ,   Department of Information Technology, Greater Noida Institute Of Technology (Engineering Institute) Greater Noida, India, Bhardwaj Parth ,   Department of Information Technology, Greater Noida Institute Of Technology (Engineering Institute) Greater Noida, India
Published: January 2024

Forest fires present a significant threat to ecosystems, endangering both human and animal life while causing irreversible environmental damage. To address this pressing issue in this research paper introduces an innovative & Affordable forest fire detection system that utilises the HSV algorithm and various computer vision libraries with the use of AI. Our advance system aims to detect & respond to forest fires in real-time, mitigating potential harm to flora and fauna. Our proposed System employs deploy camera sensors distributed at the Sensitive Parts of the forest, continually monitoring the environment. The HSV algorithm enhances the system's capability to accurately identify fire-related hues, ensuring reliable fire detection. Upon detecting a fire, an automatic alarm is triggered, initiating a series of measures to protect the ecosystem proactively. In response to a detected fire, the system automatically reroutes animal pathways to minimize their exposure to danger. Concurrently, the system sends immediate notifications to the local fire department and forest authorities via direct email, providing vital information on the fire's location and severity. This rapid communication facilitates timely intervention and improves the chances of successful firefighting efforts. We can put our system at Jim Corbett National Park & at different Sensitive forest Regions. Furthermore, the system features live monitoring capabilities, enabling authorities to observe the fire's real-time progression. This live feed supports informed decision making and facilitates the swift deployment of resources to contain and extinguish the fire. Through the integration of advanced computer vision technology, our system aims to redefine forest fire detection & response mechanisms, ultimately safeguarding the delicate balance of flora and fauna in ecosystems.
Tubuh dan Politik: Perspektif Feminis Iris Marion Young
Authors: Laku Silvester Kanisius
Published: January 2024

Artikel ini mengeksplorasi pemikiran salah seorang tokoh politik feminis kontemporer, Iris Marion Young tentang tubuh, serta menganalisis dinamika kekuasaan, ketidaksetaraan, dan pengalaman alienasi sosial, budaya, dan politik. Young menyatakan bahwa tubuh melampaui fisikalitas, ia muncul sebagai lokus politik. Kekuasaan, katanya, beroperasi pada tubuh melalui norma-norma sosial, harapan budaya, dan kebijakan, membentuk cara individu memahami dan mengalami tubuh mereka. Norma-norma ini, digambarkan sebagai sumber ketidaksetaraan dalam pengalaman tubuh, berkontribusi pada pembentukan hierarki sosial-politik dalam masyarakat. Memahami potensi dan kapasitas tubuh memiliki pengaruh politik signifikan dalam menentukan eksistensi perempuan dalam kerangka masyarakat. Makalah ini bertujuan untuk mendeskripsikan dan menganalisis konsep politik feminis Young dan menyoroti implikasi politisnya terkait peran perempuan dalam masyarakat. Penelitian ini dimulai dengan asumsi bahwa, melalui self-transcendence dan pemahaman terhadap kapasitas tubuh untuk menolak immanence, perempuan dapat menegaskan keberadaan mereka dalam masyarakat. Berakar pada keyakinan bahwa, sebagai subyek politik, semua manusia secara inheren setara, Young menantang paradigma tradisional peran sosial dan politik, menawarkan perspektif radikal tentang tubuh dan kapasitas pemberdayaan diri untuk hidup bersama yang lain. Untuk mencapai tujuan ini, penulis menggunakan metodologi tinjauan literatur, menekankan elemen-elemen metode penelitian filosofis seperti hermeneutika, deskripsi, analisis induktif dan deduktif, serta analisis koherensi gagasan Young. Artikel ini memberikan kontribusi pada wacana berkelanjutan tentang filsafat feminis, menawarkan eksplorasi komprehensif tentang pemikiran berpengaruh Young tentang dimensi politik tubuh dan implikasinya bagi peran perempuan dalam masyarakat.
Scientific Integrity in Educational Research Processes
Authors: Canchola González José Antonio , Medina Zuta Patricia , Barón-Velandia Benjamín
Published: January 2024

The academic and scientific community must conduct research with the accountability, ethics, truthfulness, integrity, and respect that is necessary. The omission or lack of academic integrity on the part of researchers is influenced by several variables: key abilities, such as those required for finding, choosing, and validating trustworthy sources of information to enable the creation of scientific articles.

On the other hand, educational institutions and research-related organizations can have an impact on the development or destruction of academic integrity through a variety of incentive programs for scientific output that support the concept of "publish or perish." They make it quite evident that in the research endeavors of thousands of scholars around the world, academic integrity is simply theoretical and unapplied.
Utilization of the Wondering, Exploring, and Explaining (WEE) Learning Model Assisted by GeoGebra to improve Understanding of Mathematical Concepts
Authors: Faradiba Surya Sari , Walida Sikky El , Alifiani Alifiani , Sari Fadhila Kartika , Ilmi Yuli Ismi Nahdiyati , Khairunnisa Gusti Firda , Syabrina Dafa Atrian
Published: January 2024

This study aims to describe the application of the Geogebra-assisted Wondering, Exploring, and Explaining (WEE) learning model in improving the ability to understand mathematical concepts on lines and angles material at Junior High School of Darush Sholihin Batu in the 2022/2023 academic year. The study employs practical classroom action research, recruiting class VII-B as the research subjects. Interview guides, observation sheets, end-of-cycle test questions adapted to indicators of the ability to understand concepts, and field notes were the study's pilots for data collection. The findings showcased that the observation of teachers' and students' activities, the final cycle test completeness, and the interview results with happy students were boosted from cycles I to II. Furthermore, cycle II met the indicators of action success, indicating that the Geogebra-assisted Wondering, Exploring, and Explaining (WEE) learning model can improve the ability to understand mathematical concepts on lines and angles material at SMP Darush Sholihin Batu.