bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of Coupling Synergy Level Between Regional Development and Ecological Environment: A Case Study of Chengdu-Chongqing Dual-City Economic Circle, China
Authors: Duan Yujing , Liang Yuan , Wang Zhong , Ji Qingyun
Published: February 2025

The increasing tensions between urban development and ecological environments in China, as evidenced by the country’s rapidly globalising and urbanising society, pose significant challenges to the implementation of sustainable development strategies. In order to evaluate the coupled coordination degree (CCD) between regional development (RD) and ecological carrying capacity (ECC) within the Chengdu-Chongqing Twin Cities Economic Circle, this study proposes a comprehensive CCD evaluation framework. This framework includes indicator analysis, quantitative measurement of coupling coordination, identification of coupling types, and evaluation of coordination impacts. The results indicate that regional development is on a growth trajectory while ecological carrying capacity lags behind. The coupling coordination has shifted from a state of ’basically uncoordinated’ to ’basically coordinated’, exhibiting a decreasing gradient in spatial distribution, with core cities demonstrating leadership. The study thus provides a set of optimised strategies tailored to cities at different stages of development, offering a theoretical foundation and decision-making framework for promoting quality development within the Chengdu-Chongqing Twin Cities Economic Circle.
Comparative Analysis and Optimization of LID Practices for Urban Rainwater Management: Insights from SWMM Modeling and RSM Analysis
Authors: Mai Yepeng , Ma Xueliang , Cheng Fei , Mai Yelin , Huang Guoru
Published: February 2025

Urbanization necessitates Low Impact Development (LID) practices for sustainable development, but existing studies lack analysis about the comprehensive effect and optimal allocation of LID combination practices. To address this gap, this study conducted an in-depth analysis of the runoff control effects of individual and combined LID practices and pollutants under varying retrofit proportions, utilizing the Storm Water Management Model (SWMM). Four evaluation metrics were employed for parameter calibration and validation assessment to ensure the accuracy of the SWMM. The Response Surface Methodology (RSM) was then employed to optimize the retrofit proportions of LID practices due to its high efficiency and statistical rigor. The results showed that, under the same retrofit ratio, bio-retention (BC) has a better runoff reduction rate and pollutant removal rate. For example, when the retrofit proportion is 100%, the runoff pollutant removal rates of BC in Parcel 1 and Parcel 2 are 29.6% and 32.9%, respectively. To achieve a 70% runoff control rate, the optimal retrofit proportions for Parcel 1 were 67.5% for green roofs (GR), 92.2% for permeable pavements (PP), 88.9% for bio-retention cells (BC), and 50% for low-elevation greenbelts (LEG); these correspond to the proportions for Parcel 2 that were 65.1%, 68.1%, 82.0%, and 50%, respectively. In conclusion, this study provides scientific and technical support for urban planners and policymakers in urban rainwater management, especially in similar regions.
Suitable Design Guidelines of City Tourism Site for Public Service: Optimization Design of Marina in Tianjin, China
Authors: Zhao Ying , Cui Canyichen , Han Meng , Zhang Yin , Liu Xiaojun , Lin Yijie
Published: February 2025

As urbanization accelerates in developing countries and populations continue to grow, the demand for sustainable urban regeneration becomes increasingly urgent. This study explores how urban regeneration can be integrated with tourism development to promote sustainable and inclusive growth. Using the theory of organic regeneration, this study emphasizes the role of localized, small-scale interventions that enhance the urban environment while boosting tourism appeal. Through field research at the Tianjin Cruise Terminal, this study applies the KANO model to classify user needs and prioritize design interventions based on the needs of various user groups, including tourists, exercisers, anglers, and local residents. By analyzing user group activity frequencies, the study identifies Must-be, One-dimensional, and Attractive needs, and utilizes weight analysis to assess the impacts of different facilities on user satisfaction. This approach ensures that the design guidelines effectively address both essential and value-enhancing features. The findings provide more suitable design guidelines for improving tourism infrastructure, promoting sustainable development, and enhancing the overall urban experience.
The Prevalence of Maxillary and Mandibular Exostosis in the Mississippi Population: A Retrospective Study
Authors: Wilson Landon , Snyder Dalton , Griggs Jason , Kurt-Bayrakdar Sevda , Bayrakdar İbrahim Şevki , Jagtap Rohan
Published: February 2025

Purpose: The objective of this study was to determine the prevalence of exostosis in the Mississippi population. Methods: The patient archives of the UMMC School of Dentistry between January 2018 and May 2021 were examined. Patients with exostosis were included in the study based on the findings from intraoral photographs, full-moth series (FMS), panoramic radiographs, and cone-beam computerized tomography (CBCT) images of the patients. Patients were excluded from the study if they did not have maxillary or mandibular exostosis. In addition, each patient’s age, gender, and ethnic origins, such as Caucasian, African-American, or Asian, were recorded. All data regarding exostosis were evaluated and categorized according to age, gender, and ethnicity. Multiple logistic regression analysis was performed for more detailed statistical analysis. Results: A total of 1242 patients were examined for the presence of maxillary and mandibular tori. In total, 303 patients were diagnosed with maxillary and/or mandibular tori among the Mississippi population, with a prevalence rate of 24.4%. Exostosis was seen more in females (57.4%) compared to males (42.6%). The highest prevalence of exostosis was seen in Caucasians (71.3%), followed by African-Americans (23.8%) and Asians (5%). Conclusions: High prevalence of exostosis was seen in the Mississippi population. Our findings will help clinicians to be more aware of these bony protuberances and, thus, better at diagnosing them. This may specifically help oral surgeons, periodontists, and prosthodontists in pre-prosthodontic surgery and denture fabrication.
Reconstruction of Scalp Defects with Rotational Flaps: Where Is the Limit?
Authors: Seretis Konstantinos , Bounas Nikos , Lykoudis Efstathios G.
Published: February 2025

Background/Objectives: Scalp defect reconstruction often poses a challenge due to the distinct anatomy and limited skin elasticity of the region. Rotational flaps, when properly planned, offer a superior and creative solution for effectively covering most scalp defects. The aim of this study is to present the indications, and versatile use of rotational flaps in scalp reconstructive surgery, guided by an algorithmic approach and exemplified by numerous clinical applications. Methods: An observational cohort study was conducted between 2019 and 2024. The study protocol adhered to the ethical guidelines of the Declaration of Helsinki, was approved by the local ethics committee, and followed the STROBE statement for cohort studies. Results: A total of 152 rotational flaps were performed in 138 patients to reconstruct scalp defects, mostly following skin cancer excision. The defect size ranged from 30 to 96 mm in largest diameter (mean diameter, 52.8 ± 8.8 mm). Postoperative complications occurred in 13 cases (9.4%), and 5 cases (3.6%) required further surgical treatment, due to wound healing problems and/or necrosis. Based on high VAS scores (9.4 + 0.3), the cosmetic outcomes were deemed satisfactory, with excellent color and texture matching. Conclusions: This study underscores the critical role of meticulous surgical planning and technique in achieving optimal outcomes in scalp reconstruction. By combining the principles of tissue biomechanics with the versatility of rotational flaps, surgeons can effectively address a wide range of defects, achieving both functional and esthetic excellence.
Lie Group Classification, Symmetry Reductions, and Conservation Laws of a Monge–Ampère Equation
Authors: Samina Samina , Arif Faiza , Jhangeer Adil , Wali Samad
Published: February 2025

The nonhomogeneous Monge–Ampère equation, read as wxxwyy−wxy2+h(w)=0, is a nonlinear equation involving mixed second derivatives with respect to the spatial variables x and y, along with an additional source function h(w). This equation is observed in several fields, including differential geometry, fluid dynamics, and magnetohydrodynamics. In this study, the Lie symmetry method is used to obtain a detailed classification of this equation. Symmetry analysis leads to a comprehensive classification of the equation, resulting in specific forms of the smooth source function h(w). Furthermore, the one-dimensional optimal system of the associated Lie algebras is derived, allowing for symmetry reductions that yield several exact invariant solutions of the Monge–Ampère equation. In addition, conservation laws are constructed using the Noether approach, a highly effective and widely used method for deriving conserved quantities. These conservation laws can help evaluate the accuracy and reliability of numerical methods.
Combining MAMBA and Attention-Based Neural Network for Electric Ground-Handling Vehicles Scheduling
Authors: Li Jiawei , Fu Weigang , Huang Gangjin , Liu Kai , Zhang Jiewei , Fu Yaoming
Published: February 2025

To reduce airport operational costs and minimize environmental pollution, an increasing number of airports are transitioning from fuel-powered to electric ground-handling vehicles. However, the limited battery capacity of electric vehicles and the need for charging make the scheduling of these vehicles more complex. To address this scheduling problem, this paper proposes an electric ground-handling vehicle scheduling algorithm that combines the MAMBA model with an attention-based neural network. The MAMBA model is designed to process multi-dimensional features such as flight information, vehicle locations, service demands, and time window constraints. Subsequently, an attention mechanism-based neural network is developed to dynamically integrate vehicle states, service records, and operational and charging constraints, in order to select the most suitable flights for electric ground-handling vehicles to service. The experiments use flight data from Xiamen Gaoqi International Airport and compare the proposed method with CPLEX solvers, existing heuristic algorithms, and custom heuristic algorithms. The results demonstrate that the proposed method not only effectively solves the electric ground-handling vehicle scheduling problem and provides high-quality solutions, but also exhibits good scalability in different parameter settings and real-time scheduling scenarios.
Coupled Water–Energy–Carbon Study of the Agricultural Sector in the Great River Basin: Empirical Evidence from the Yellow River Basin, China
Authors: Song Jingwei , Cong Jianhui , Liu Yuqing , Zhang Weiqiang , Liang Ran , Yang Jun
Published: February 2025

In the context of sustainable development, water resources, energy, and carbon emissions are pivotal factors influencing the rational planning of economic development and the secure establishment of ecological barriers. As a core food production area, how can the Great River Basin balance the pressure on the “water–energy–carbon” system (WEC) to realize the coordinated development of “nature–society–economy”? Taking the Yellow River Basin in China as the research object, this paper explores the coupling characteristics and virtual transfer trends of WEC in the agricultural sector under the condition of mutual constraints. The results show the following: (1) On the dynamic coupling characteristics, W-E and E-C are strongly coupled with each other. The optimization of water resource allocation and the development of energy-saving water use technology make the W-E consumption show a downward trend, and the large-scale promotion of agricultural mechanization makes the E-C consumption show an upward trend. (2) On the spatial distribution of transfer, there is an obvious path dependence of virtual WEC transfer, showing a trend of transfer from less developed regions to developed regions, and the coupling strength decreases from developed regions to less developed regions. The assumption of producer responsibility serves to exacerbate the problem of inter-regional development imbalances. (3) According to the cross-sectoral analysis, water resources are in the center of sectoral interaction, and controlling the upstream sector of the resource supply will indirectly affect the synergistic relationship of WEC, and controlling the downstream sector of resource consumption will indirectly affect the constraint relationship of WEC. This study provides theoretical and methodological references for the Great River Basin to cope with the resource and environmental pressure brought by global climate change and the effective allocation of inter-regional resources.
ADMM-TransNet: ADMM-Based Sparse-View CT Reconstruction Method Combining Convolution and Transformer Network
Authors: Wang Sukai , Sun Xueqin , Li Yu , Wei Zhiqing , Guo Lina , Li Yihong , Chen Ping , Li Xuan
Published: February 2025

Background: X-ray computed tomography (CT) imaging technology provides high-precision anatomical visualization of patients and has become a standard modality in clinical diagnostics. A widely adopted strategy to mitigate radiation exposure is sparse-view scanning. However, traditional iterative approaches require manual design of regularization priors and laborious parameter tuning, while deep learning methods either heavily depend on large datasets or fail to capture global image correlations. Methods: Therefore, this paper proposes a combination of model-driven and data-driven methods, using the ADMM iterative algorithm framework to constrain the network to reduce its dependence on data samples and introducing the CNN and Transformer model to increase the ability to learn the global and local representation of images, further improving the accuracy of the reconstructed image. Results: The quantitative and qualitative results show the effectiveness of our method for sparse-view reconstruction compared with the current most advanced reconstruction algorithms, achieving a PSNR of 42.036 dB, SSIM of 0.979, and MAE of 0.011 at 32 views. Conclusions: The proposed algorithm has effective capability in sparse-view CT reconstruction. Compared with other deep learning algorithms, the proposed algorithm has better generalization and higher reconstruction accuracy.
Effects of Exposure to Different Types of Microplastics on the Growth and Development of Rana zhenhaiensis Tadpoles
Authors: Xiao Shimin , Chen Hao , Gao Xiyao , He Xinni , Jin Rongzhou , Wei Yunqi , Li Shuran , Xie Lei , Zhang Yongpu
Published: February 2025

Microplastic (MP) pollution is a major environmental problem, but a comparative study of the toxicological effects of different MPs remains lacking. To explore the toxicological effects of three different microplastics, namely, polypropylene (PP), polystyrene (PS) and polyethylene (PE), Zhenhai brown frog (Rana zhenhaiensis) tadpoles were used as the model animal. The results showed that exposure to PE and PS significantly reduced the metamorphosis rate of the tadpoles. Compared with the control group, the body weight of tadpoles in all MP treatments was significantly reduced compared with that of the control group. In addition, exposure to PE reduced the body length and hind limb length of tadpoles. The number of pigment cells increased and intercellular spaces expanded in the liver tissues of tadpoles receiving PS and PE treatments. The composition and function of the intestinal microbiota in the PP treatment and control groups were similar, whereas between the PS treatment and control, they differed. Liver transcriptome sequencing revealed significant alterations in key genes associated with oxidative stress, energy metabolism, immune response, and apoptosis signaling pathways with PS treatment and PP treatment. In summary, MPs may have harmed tadpoles to varying degrees by interfering with related signaling pathways. The negative effects of PE and PS were greater than those of PP.
In Vitro System for Studying Ilhéus Virus, a Neglected Arbovirus: Ultrastructural Characterization of Cytopathology, Morphology, and Morphogenesis
Authors: Garcia Maycon Douglas do Nascimento , Da Costa Igor Pinto Silva , da Silva Marcos Alexandre Nunes , Ferreira Vivian Neuza dos Santos , de Almeida Ana Luisa Teixeira , Caldas Gabriela Cardoso , de Almeida Andressa Santos , de Filippis Ana Maria Bispo , Fintelman-Rodrigues Natalia , Silva Aline de Paula Dias da , Alves Ferreira Marcelo , Souza Thiago Moreno L. , Pauvolid-Corrêa Alex , Barreto-Vieira Debora Ferreira
Published: February 2025

Ilhéus Virus (ILHV) was first detected in 1944 in Ilhéus, state of Bahia, northeast Brazil. During cellular infection, orthoflaviviruses induce cellular changes related both to the replication process, the formation of replication complexes, and to structures resulting from cellular damage. Although more detailed data are available in the literature for other orthoflaviviruses, the relationship between ILHV, the formation of these structures, its replication cycle, and cellular changes remains unknown. One of the main objectives of this study is to characterize the primary ultrastructural changes in green monkey kidney epithelial cell lineage (Vero cell) infected with ILHV, as well as to map its replication cycle, virion structure, and genome. To achieve these objectives, Vero cell monolayers were infected with an MOI of 0.01 and collected at different times post-infection. Cell monolayers were evaluated under bright-field microscopy and transmission electron microscopy. Ultrastructural analyses confirmed that ILHV can induce the formation of double-membrane vesicles, convoluted membranes, and vesicular packets. These structures, like those observed in zika (ZIKV) and dengue (DENV) viruses, form replication complexes that aid ILHV’s replication process in cells. Our preliminary results reveal that ILHV infection induces cytopathogenesis like that observed in vitro studies for other arboviruses.
Epidemiological Characteristics of the African Swine Fever Genotype II Epidemic in Domestic Pigs in Lombardy (Northern Italy) in 2023 and 2024
Authors: Bellini Silvia , Salvato Sara , Bernardis Martina , Chiari Mario , Martinello Federico , Galimberti Luigi , Maggiano Valentina , Feliziani Francesco , Farioli Marco , Alborali Giovanni Loris
Published: February 2025

African swine fever (ASF) is a severe hemorrhagic disease of suids caused by the African swine fever virus (ASFV). In 2023, the introduction of genotype II ASFV into Lombardy was a cause for serious concern; the region is home to approximately 50% of the national pig population and is of economic importance to the processing industry of the entire country. Since then, two ASF epidemics have resulted in a total of 30 outbreaks in domestic pigs in the same areas of Lombardy, where the disease is endemic in wild boars. The results of the control activities conducted in the affected areas seem to indicate the establishment of self-sustaining infection cycles in the wild boar population with spillover and spillback events occurring between wild boars and domestic pigs. This manuscript describes some epidemiological features of the ASF epidemics in Lombardy with the aim of providing useful information to combat the disease.
The Identification of Dual T-Cell and B-Cell Epitopes Within Viral Proteins Utilizing a Comprehensive Peptide Array Approach
Authors: Liu Binghang , Bai Muqun , Zheng Fei , Yan Mingchen , Huang Enen , Wen Jie , Li Yingrui , Wang Jun
Published: February 2025

Background/Objectives: The development of vaccines that elicit both T-cell and B-cell responses is crucial for effective immunity against pathogens. This study introduces a novel approach to identify precise epitope peptides within viral proteins that can stimulate both arms of the adaptive immune response, using Porcine Parvovirus (PPV) as a model. Methods: Mice were infected with PPV, and a peptide array was utilized to detect IgG signals in their sera. This approach facilitated the assessment of the immunogenicity of the PPV proteome, leading to the identification of 14 potential epitope candidates. These candidates were then used to immunize additional mice, and their ability to induce T-cell and B-cell responses was evaluated. Results: The immunization experiments identified an optimal peptide, P6, which robustly activated both T cells and B cells. Further analysis of the sub-regions of this peptide confirmed P6 as the most potent inducer of immune responses. The anticipated epitope was detected in mice immunized with P6, highlighting the efficacy of our method in identifying epitopes that engage both T cells and B cells. Conclusions: This study presents a novel strategy for the identification of dual T-cell and B-cell epitopes by directly evaluating the immunoreactivity of antibodies in serum. This finding holds significant promise for the advancement of epitope-based vaccines.
Respiratory Vaccines in Older Adults: A Bibliometric Analysis and Future Research Agenda
Authors: Parodi Jose F. , Runzer-Colmenares Fernando , Cano-Gutiérrez Carlos , Dinamarca-Montecinos José Luis , Torre Patricio Bendía-Gomez de La , Villas Boas Paulo Fortes , Flores-Cohaila Javier , Urrunaga-Pastor Diego , Gutiérrez-Robledo Luis Miguel
Published: February 2025

Background/Objectives: Respiratory infections impact older adults due to immunosenescence and comorbidities, resulting in increased healthcare costs and mortality. While vaccination is a critical preventive measure, research on respiratory vaccines in older adults in Latin America and the Caribbean (LAC) remains underexplored. This study aims to map the research landscape and identify emerging themes to guide future studies. Methods: A bibliometric analysis was conducted using the Web of Science database, focusing on publications up to 2023 related to respiratory vaccines in LAC’s older adult population. PRISMA-ScR guidelines were followed for data extraction and analysis, with performance metrics and scientometric mapping conducted using Biblioshiny 4.1 and VOSviewer. Results: Ninety-nine studies spanning forty-one journals and 575 authors were included. Brazil contributed 70% of publications, followed by Mexico and Argentina. Influenza and pneumococcal vaccines were the most studied, focusing on coverage, acceptance, and cost-effectiveness. Emerging themes included COVID-19 vaccine effectiveness and vaccination-associated factors. Brazil was identified as the primary hub for collaboration across the region, while other countries made limited contributions. Conclusions: The findings highlight disparities in research output, with Brazil dominating and significant gaps in other LAC countries. Future research should prioritize genomic studies, vaccine efficacy in comorbid populations, and adaptive immunization strategies. Building research capacity and fostering international collaborations are essential for improving vaccination outcomes in older adults across LAC.
The Effects of Xanthan Gum as a Synergistic Delivery Reagent on Perchloroethylene Remediation in Lower-Permeability Zones of Aquifers
Authors: Xu Qi , Jia Zhuofei , Wen Xiaogang , Xiao Yanping , Zhong Haobin , Chen Jiajun
Published: February 2025

Treating contamination plumes in relatively lower-permeability zones (LPZs) presents a significant challenge for injection-based remediation due to aquifer heterogeneity. Currently, xanthan gum, as a co-remediation agent, has been confirmed to enhance the removal efficiency of contaminants in these zones. However, its associated effects on plume migration remain to be clarified. This study revealed the mechanisms by which xanthan addition enhances the removal rate of perchloroethylene (PCE), as well as its effects on plume migration. The results demonstrated that the injection of xanthan induces adverse migration of contamination plumes. A nonlinear relationship was observed between xanthan concentration, injection rate, and remediation performance. Within the studied range (0 g/L–0.8 g/L; 10 mL/min–40 mL/min), an optimal xanthan concentration (0.8 g/L) and injection rate (25 mL/min) were identified, at which the PCE removal efficiency was significantly improved, and the contamination plume migration was effectively inhibited. For combinations of porous media with a lower permeability contrast, adding xanthan led to better performance. To provide a comprehensive assessment of the remediation performance, four key indicators were proposed: remediation measurement factor, PCE removal rate, sweeping uniformity, and injection pressure. The results identified the optimal remediation conditions: M-F combination with the lowest permeability contrast (4.9), 0.4 g/L xanthan, and an injection rate of 25 mL/min. These findings contribute valuable insights for the formulation of more efficient remediation strategies.
FOREST VEGETATION IN THE MODERN NATURE RESERVE NETWORK OF THE SNOV RIVER BASIN (WITHIN UKRAINE)
Authors: Asmakovskyi Y. , Karpenko Yu.
Published: February 2025

The article provides a brief description of forest vegetation in the modern structure of the nature reserve fund of the Snov River basin. The network of nature reserves in the study region includes 90 forest objects of various statuses and categories with a total area of 13,330.7 ha within the Chernihiv, Koriukivka and Novhorod-Siverskyi districts. The first two objects of the nature reserve fund of the study area were created in 1958, and the vast majority in the period from 1975 to 2000. The largest category of the nature reserve fund in terms of number and area are reserves – 63 (two of which have state protection status) with an area of 10,250.9 ha; The second position is occupied by protected tracts – 11 sites with a total area of 5890.1 hectares and natural monuments – 11 (two of which have national protection status) with an area of 138.7 hectares. The largest number of protected forest areas of the Snov River basin is located in the Koriukivka district (49 objects, with a total area of 1935.5 ha, the percentage of reserves within the district is 0.79%), the middle position is occupied by the Chernihiv district (23 objects, 7147.5 ha, 3%), the last is the Novhorod-Siverskyi district (18 objects, 4247.7 ha, 2.47%). The distribution of forest vegetation within protected areas is determined mainly by edaphic and hydrological factors, which are significant in the formation of forest vegetation of the Snov River basin, its floristic and coenotic composition. The forest cover of the research area, which has a protected status in terms of coenotic composition, is mainly pine, oak-pine and alder forests with a different floristic set, and areas with spruce are found fragmentarily. The sustainability, functionality and value of the forest areas of the basin are determined by the species composition, rare components, cenotic diversity, and role in the formation of landscape complexes of the relevant territories, and form an integral part of the Chernihiv region nature reserve fund, within which an appropriate regime of preservation, protection, restoration and use is established.
CLEMATIS IN URBAN LANDSCAPES OF POLTAVA: VARIETY AND MORPHOLOGICAL PROFILE
Authors: Kovalenko N. , Pospielova G. , Samorodov V.
Published: February 2025

The study presents the results of research on the variety of clematis grown in the urban landscapes of Poltava. It was found that the varieties studied are the result of the work of breeding centers in the United Kingdom, Poland and the Netherlands (each comprising 20%), as well as Japan and Sweden (each comprising 10%), and Germany, France, Estonia and Ukraine (each comprising 5%). It was found that preference is given to well-known varieties that have been cultivated in Ukraine for a long time: 5 varieties have been known since the 19th century (Netherlands – 2, the United Kingdom, France and Sweden – 1 each), and 11 varieties since the second half of the 20th century. (Poland – 4, the United Kingdom – 3, Estonia, the Netherlands, Ukraine, Japan and Sweden – 1 each). The modern varieties (XXI century) include 2 varieties from the Netherlands and Germany. The studied clematis varieties differ by taxonomic position and geographical origin. Based on natural distribution areas, European-bred varieties dominate the sample, with only one representing Japanese selection. It was found that the varieties belong to four horticultural groups: Patens, Florida, Viticella, and Jackmanii. Their quantitative composition is heterogeneous: 10 varieties (50% of the total number of the studied varieties) belong to the Patens group; 5 varieties (25%) to Jackmanii; 3 varieties (15%) to Viticella; and 2 varieties (10%) to Florida. Data from route surveys enabled the grouping of clematis varieties by pruning groups. Attention is drawn to the fact that mainly varieties of the 2nd and 3rd pruning groups are grown. The third group includes 4 varieties: Mefistofel, Polish Spirit, Ville de Lyon, and Rosamunde.Nelly Moser, Liberty, and Mrs Cholmondeley belong to both the 2nd and 3rd groups. The remaining varieties fall into the 2nd pruning group. It was established that all varieties studied are deciduous shrub vines, differing in height. The tall varieties (vines up to 4 meters) include Mefistofel, Jan Pawel II, Polish Spirit, Ville de Lyon and Mrs Cholmondeley. Piilu and Rosamunde are characterized by shoots up to 1.5 meters in length and are considered short. The rest of the varieties have medium-length shoots. The varieties studied by us grow well in the region of the research, therefore, they are recommended to be integrated into the practice of sustainable horticulture.
Гарантії захисту трудових прав викривачів: міжнародний досвід та актуальна національна судова практика
Authors: Кайда Н. Я. , Дубас Д. І.
Published: February 2025

У статті досліджено гарантії захисту трудових прав викривачів у контексті боротьби з корупцією. Звернута увага, що гарантії захисту трудових прав викривачів є ключовим інструментом у боротьбі з корупцією. Виявлені основні в Україні проблеми в їх реалізація, зокрема є прогалини у законодавстві, нечіткість визначень термінів, складність процедур, відсутність ефективних механізмів захисту та недостатня обізнаність працівників і роботодавців. Вказано, що ці недоліки створюють бар’єри для викриття корупційних правопорушень, а також призводить до випадків переслідування викривачів.
Розглянуто актуальну судову практику, зокрема рішення КЦС ВС, яке підкреслює важливість захисту викривачів від негативного впливу роботодавців. В результаті проведеного дослідження відмічена готовність судів захищати права викривачів, включно із поновленням на роботі та компенсацією збитків. Така позиція судової влади сприяє зміцненню довіри до судової системи та мотивує громадян повідомляти про корупцію.
Виявлено основні проблеми: прогалини у законодавстві, відсутність ефективних механізмів реалізації гарантій та недостатню обізнаність працівників і роботодавців. Водночас наголошено на позитивних тенденціях у судовій практиці, що сприяють зміцненню довіри до судової системи. Для ефективного захисту викривачів в статті пропонується  вжити заходів до вдосконалення національного законодавства, на необхідності гармонізації його з міжнародними стандартами, розробки чітких процедур захисту викривачів, посиленні відповідальності за порушення прав викривачів, створити спеціалізовані органи та впровадити міжнародні стандарти захисту викривачів.
Щодо застосування спеціальних засад призначення покарання при його призначенні за вчиненні діяння, передбаченого ч. 1. ст. 152 КК України
Authors: Шинкарьов Ю. В.
Published: February 2025

Пропонована стаття присвячена дослідженню застосування спеціальних засад призначення покарання за вчинення діяння, передбаченого ч. 1 ст. 152 чинного Кримінального кодексу України. У статті констатується, що у значній кількості сучасних наукових робіт, присвячених дослідженню інституту призначення покарання, науково обґрунтовується наявність субінституту спеціальних засад призначення покарання. При чому, незважаючи на це, значна кількість питань з ними пов’язаних, досі залишається поза увагою сучасних вчених у галузі кримінального права. В статті щодо цього визначається, що у сучасній правовій літературі відсутній аналіз застосування спеціальних засад призначення покарання при його застосуванні за вчинення конкретного кримінального правопорушення. Одним із них є склад кримінального правопорушення, передбачений ч. 1 ст. 152 КК України. Метою пропонованої наукової статті є аналіз практики застосування спеціальних засад призначення покарання на ґрунті дослідження практики правозастосування. Пропонуються основні підходи до визначення поняття спеціальних засад призначення покарання. Констатується значення спеціальних засад для реалізації принципу індивідуалізації покарання. Окреслюються основні підходи до визначення переліку або системи спеціальних засад призначення покарання. Визначається, що базою для проведення дослідження виступають 100 вироків суду про призначення покарання, за вчинення діяння передбаченого ч. 1 ст. 152 КК України протягом 2019-2024 років. При проведенні дослідження за основу взятий більш широкий перелік спеціальних засад призначення покарання, який пропонується у літературі. В процесі дослідження встановлено, що окремі спеціальні засади призначення покарання не застосовувалися під час його призначення за вчинення діяння, окресленого у ч. 1 ст. 152 КК України, хоча законом передбачена така можливість. Визначені спеціальні засади призначення покарання, що не можуть бути застосовані з огляду на конструкцію складу кримінального правопорушення, передбаченого ч. 1 ст. 152 КК України. Визначена група спеціальних засад, що застосовуються частіше за все при призначенні покарання за вчинення діяння, передбаченого ч. 1 ст. 152 КК України. Робиться висновок про значний індивідуалізуючий потенціал спеціальних засад призначення покарання.
Сучасний погляд на підстави визнання доказів недопустимими у кримінальному процесі України
Authors: Цімура Я. В.
Published: February 2025

У статті висвітлено результати наукового дослідження сучасних підходів до визначення підстав визнання доказів недопустимими в кримінальному процесі України. Проаналізовано позиції вітчизняних науковців з зазначеного предмета дослідження. За результатами їх критичної оцінки сформульовано власний підхід до визначення кола критеріїв недопустимості доказів. У роботі також приділено увагу проблемі істотності та неістотності порушень кримінальної процесуальної форми та їх впливу на визнання доказів недопустимими у їх нерозривному зв’язку із поняттям очевидної та неочевидної недопустимості доказів. Зокрема до очевидно недопустимих доказів слід в першу чергу відносити ті фактичні дані, недопустимість яких прямо визначена законом, де це ті порушення, які безпосередньо передбачені КПК України. Доведено, що істотність порушення кримінальної процесуальної форми прямо визначена законодавцем, у зв’язку із чим суду не потрібно досліджувати істотність чи неістотність такого порушення, адже статус таких порушень презюмується законодавцем. Всі інші можливі порушення, які не презюмуються законодавцем повинні становити  предмет судового дослідження щодо їх недопустимості. Вказується, що саме право суду у разі встановлення очевидної недопустимості доказу припинити його дослідження в судовому засіданні або не досліджувати взагалі є важливою гарантією використання допустимих доказів в кримінальному процесі України. Зазначено про закладену на законодавчому конструкцію презумпції істотності порушень кримінальної процесуальної форми, що породжує очевидну недопустимість доказів.
“Eu não sou mulher de Lucifér, sou mãe de Lucifér”:
Authors: Regis Eduardo
Published: February 2025

A Umbanda é uma religião híbrida que traz para si elementos de diferentes fontes e que é principalmente caracterizada pela sua paleta colorida de espíritos, dentre os quais se destacam exu e sua contraparte feminina: pombagira. A relação entre pombagira e a Umbanda passa necessariamente pela sua inequívoca associação ao feminino como algo perigoso, livre e que não se presta às convenções sociais. Entretanto, a plasticidade de pombagira não pode ser restrita. Em uma visita ao Centro Espírita Estrela Guia (Tijuca, Rio de Janeiro/RJ), a pombagira chefe da casa, Pombagira Dona Figueira, em entrevista exibiu sua face maternal, subvertendo as expectativas mais ordinárias acerca do imaginário de Pombagira. Neste artigo, são apresentadas reflexões acerca da noção de Pombagira em Umbanda e Quimbanda, seguindo as revelações de Dona Figueira, que se costuram de maneira surpreendente e complexa a elementos católicos, de bruxaria e, claro, de brasilidade.
Caminhos Hermenêuticos de Dioniso
Authors: Telles Luana
Published: February 2025

Este artigo propõe uma análise hermenêutica dos símbolos associados ao deus Dioniso na religião da Grécia Antiga, examinando como esses símbolos são interpretados tanto em contextos empíricos quanto teóricos. Ao utilizar as abordagens hermenêuticas de Paul Ricoeur e Martin Heidegger, como o dossiê sugere, é possível explorar como os símbolos dionisíacos, incluindo rituais, mitos e representações artísticas, servem como meios para acessar e construir significados religiosos e ontológicos. A metodologia envolve a análise de textos antigos, como As Bacantes e hinos órficos, além de estudos contemporâneos de autores como Marcel Detienne, Jean Pierre Vernant e Walter Burkert. Os resultados mostram que o simbolismo de Dioniso é multifacetado e reflete diversas tensões e complexidades da espiritualidade grega. Este estudo destaca a importância de uma abordagem hermenêutica para desvendar as camadas de significados que esses símbolos carregam, convidando os leitores a reconsiderar a maneira como interpretamos as divindades e suas representações no contexto cultural e religioso da Grécia Antiga.
PENGARUH ASPEK PENGALAMAN MEREK TERHADAP CUSTOMER DELIGHT PADA PENGGUNAAN KOSMETIK DEKORATIF KOREA
Authors: Sitepu Adma Sari
Published: February 2025

The objective of this study is to examine direct impact of consumer brand experience through sensory, affective, behavioral and cognitive on the customer delight to use Korean decorative cosmetics. A survey-based data collection approach was employed, utilizing a questionnaire administered to 255 respondents in five region city of the Special Capital Territory of Jakarta. The data were analyzed using Multiple Regression Analysis. The findings indicate a positive effect of sensory and affective on the customer delight of usages of Korean decorative cosmetics. Additionally, the study reveals that the effect of behavioral and cognitive are not impactful on the customer delight . This research offers managerial insights, suggesting that marketers and stakeholders within the Indonesian cosmetics industry should develop marketing strategies that enhance consumers' emotions and foster positive attitudes toward the behavior of using Korean decorative cosmetics to incline further contributing to customer delight
Липосомальные нанотехнологии в лечении заболеваний предстательной железы
Authors: Ниткин Д.М.
Published: February 2025

В статье рассматриваются перспективы использования липосом в роли транспортной системы доставки лекарственных средств к органам-мишеням и возможность применения липосомальных нанотехнологий в урологии при лечении болезней предстательной железы. Отдельное внимание уделяется доказательной базе практического использования субстанций: липосомального эпигаллокатехина, дииндолилметана, бета-ситостерола, липосомального кверцетина, липосомального ресвератрола, липосомального пиридоксина, а также экстрактов лекарственных растений для лечения таких заболеваний, как хронический простатит, доброкачественная гиперплазия простаты, и для профилактики неопластических процессов в предстательной железе.

The article discusses the prospects of using liposomes as a transport system for delivering drugs to target organs and the possibility of using liposomal nanotechnology in urology in the treatment of prostate diseases. Special attention is paid to the evidence base for the practical use of substances: liposomal epigallocatechin, diindolylmethane, beta-sitosterol, liposomal quercetin, liposomal resveratrol, liposomal pyridoxine, as well as extracts of medicinal plants for the treatment of diseases such as chronic prostatitis, benign prostatic hyperplasia and for the prevention of neoplastic processes in the prostate.
Эстетрол – новая парадигма гормональной контрацепции
Authors: Гутикова Л.В.
Published: February 2025

Статья посвящена исследованию применения эстетрола (Е4) в составе комбинированных оральных контрацептивов (КОК) и его эффектов в организме женщины. Естественный фетальный эстроген Е4 отличается высокой биодоступностью и низким риском метаболических последствий. Проанализированные данные исследований демонстрируют, что Е4 может снижать риск развития рака молочной железы, так как его действие приводит к меньшей пролиферации клеток молочной железы по сравнению с другими эстрогенами. На фоне приема Е4 сведен к минимуму риск венозной тромбоэмболии и отмечается меньшее воздействие на печеночные ферменты, что улучшает качество сексуальной жизни и дает возможность назначать КОК с Е4 женщинам, получающим постоянно ряд лекарственных препаратов, таких как статины, антиретровирусные, противосудорожные. Представленный обзор подчеркивает перспективные результаты клинических исследований, свидетельствующих об эффективности КОК на основе Е4, что доказывает высокий уровень удовлетворенности женщин. Клиническое применение КОК с Е4 улучшает качество жизни женщин, ликвидируя отрицательные последствия, связанные с сексуальной дисфункцией, и обеспечивая высокий контроль менструального цикла. Е4 как представитель третьего поколения эстрогенов в составе КОК может обеспечить в перспективе дополнительные преимущества для здоровья женщин, что в ближайшие годы станет предметом большого интереса исследователей и будет способствовать дальнейшей персонализации безопасного использования и выбора гормональной контрацепции.

The article is devoted to the study of the use of estetrol (E4) in combined oral contraceptives (COCs) and its effects in the female body. Natural fetal estrogen E4 is characterized by high bioavailability and low risk of metabolic consequences. The analyzed research data demonstrate that E4 can reduce the risk of breast cancer, since its action leads to less proliferation of breast cells compared to other estrogens. Against the background of taking E4, the risk of venous thromboembolism is minimized and there is a lesser effect on liver enzymes, which improves the quality of sexual life and makes it possible to prescribe COCs with E4 to women who constantly receive a number of drugs, such as: statins, antiretrovirals, anticonvulsants. The presented review highlights promising results of clinical studies indicating the effectiveness of COCs based on E4, which proves a high level of satisfaction of women. Clinical use of COCs with E4 improves the quality of life of women, eliminating the negative consequences associated with sexual dysfunction and providing high control of the menstrual cycle. E4 as a representative of the third generation of estrogens in the composition of a combined oral contraceptive may provide additional benefits for women’s health in the future, which in the coming years will be the subject of great interest of researchers and will contribute to further personalization of the safe use and choice of hormonal contraception.
Фертильность и нутриативные особенности
Authors: Камлюк А.М.
Published: February 2025

В период планирования беременности образ жизни супругов, психологическая установка в семье на правильные пищевые привычки, исключение вредных и токсических влияний, обеспечение организма полезными веществами для увеличения его резервов имеют большое значение для достижения важной цели – воспроизводства здорового потомства. Пищевое поведение отражается на качестве половых клеток, как женских, так и мужских, которое во многом определяет здоровье ребенка. Вредные и токсические компоненты табачного дыма, вейп-пара, алкоголя, ряда лекарственных средств приводят к повреждениям ДНК ооцитов, сперматозоидов, эмбрионов. В результате – заметный рост обращений в клиники репродукции по поводу бесплодия и невынашивания беременности.

During the period of pregnancy planning the lifestyle of the spouses, the psychological family attitude based on rational eating habits, the exclusion of harmful and toxic influences, the provision of the body with biological substances to increase its reserves, are adjusted for the main goals – the reproduction of healthy offspring. Eating behavior affects the quality of reproductive cells, both female and male, which largely determine the health of the child. Harmful and toxic components of tobacco, vaping vapor, alcohol, and several medications lead to damage to the DNA of oocytes, sperm, and embryos. As a result, there is a noticeable increase in visits to fertility clinics regarding infertility and miscarriage.
На вершине пирамиды: центральные гормональные нарушения как провокатор нарушений менструального цикла и патологии молочной железы
Authors: Иванишкина-Кудина О. Л. , Сопич И.В.
Published: February 2025

Несмотря на тысячелетние попытки понять и изучить причины нарушений менструального цикла (НМЦ), нерегулярный, болезненный или осложненный другими отклонениями от принятой нормальности менструальный цикл пугает молодых пациенток возможными последствиями и нарушениями фертильности и поэтому служит частым поводом для обращения к врачу. В обзорной статье проведен анализ современных научных данных о патогенетических механизмах влияния центральных гормональных нарушений на развитие НМЦ и патологии молочной железы. Изучены результаты применения препарата Префемин у пациенток с данными нарушениями. Представлен обзор современных подходов к негормональному лечению НМЦ, терапевтическим вопросам применения препаратов на основе стандартизированного экстракта прутняка Ze440.

Despite millennia of attempts to understand and study the causes of menstrual cycle disorders (MCD), irregular, painful or complicated by other deviations from the accepted normality of the menstrual cycle frightens young patients with possible consequences and fertility disorders and therefore serves as a frequent reason for visiting a doctor. The review article analyzes modern scientific data on the pathogenetic mechanisms of the influence of central hormonal disorders on the development of MCD and breast pathology. The results of using the drug Prefemin in patients with these disorders were studied. A review of modern approaches to non-hormonal treatment of MCD and therapeutic issues in the use of drugs based on standardized vitex agnus extract Ze440.