bluuebunny/crossref_metadata_2025 huggingface dataset:
Restoration of Heel–Toe Gait Patterns for the Prevention of Asymmetrical Hip Internal Rotation in Patients with Unilateral Spastic Cerebral Palsy
Authors: Brunner Reinald , Taylor William R. , Visscher Rosa M. S.
Published: September 2021

Forward modelling has indicated hip internal rotation as a secondary physical effect to plantar flexion under load. It could therefore be of interest to focus the treatment for patients with unilateral spastic cerebral palsy on achieving a heel–toe gait pattern, to prevent development of asymmetrical hip internal rotation. The aim of this preliminary retrospective cohort investigation was to evaluate the effect of restoring heel–toe gait, through use of functional orthoses, on passive hip internal rotation. In this study, the affected foot was kept in an anatomically correct position, aligned to the leg and the gait direction. In case of gastrosoleus shortness, a heel raise was attached to compensate for the equinus and yet to provide heel–floor contact (mean equinus = −2.6 degrees of dorsiflexion). Differences in passive hip internal rotation between the two sides were clinically assessed while the hip was extended. Two groups were formed according to the achieved correction of their gait patterns through orthotic care: patients with a heel-toe gait (with anterograde rocking) who wore the orthosis typically for at least eight hours per day for at least a year, or patients with toe-walking (with retrograde rocking) in spite of wearing the orthosis who used the orthosis less in most cases. A Student’s t-test was used to compare the values of clinically assessed passive hip rotation (p < 0.05) between the groups and the effect size (Hedges’ g) was estimated. Of the 70 study participants, 56 (mean age 11.5 y, majority GMFCS 1, similar severity of pathology) achieved a heel-toe gait, while 14 remained as toe-walkers. While patients with heel–toe gait patterns showed an almost symmetrical passive hip internal rotation (difference +1.5 degrees, standard deviation 9.6 degrees), patients who kept toe-walking had an increased asymmetrical passive hip internal rotation (difference +10.4 degrees, standard deviation 7.5 degrees; p = 0.001, Hedges’s g = 0.931). Our clinical findings are in line with the indications from forward modelling that treating the biomechanical problem might prevent development of a secondary deformity. Further prospective studies are needed to verify the presented hypothesis.
Volatile Organic Compounds from Orchis Species Found in Basilicata (Southern Italy)
Authors: Mecca Marisabel , Racioppi Rocco , Romano Vito A. , Viggiani Licia , Lorenz Richard , D’Auria Maurizio
Published: September 2021

This study is part of a project devoted to determining the scent of all the orchid species present in Basilicata. All the analyses were performed by using the solid-phase microextraction technique coupled with gas chromatography-mass spectrometry. The scent of eight species belonging to the Orchis genus was investigated. In the case of O. anthropophora, caryophyllene, tetradecanal and hexadecanal were the main components of the aroma; in O. purpurea, 3,5-dimethoxytoluene and elemicin were found; in O. italica, caryophyllene and 4-(3-hydroxy-2-methoxyphenyl)butan-2-one were found; in O. pauciflora, linalool and 1,4-dimethoxybenzene were found; in O. mascula, linalool was found; in O. quadripunctata, penta- and heptadecane were found; in O. provincialis, β-farnesene and farnesal were found; and in O. pallens, curcumene was the main product.
3D Guided Dental Implant Placement: Impact on Surgical Accuracy and Collateral Damage to the Inferior Alveolar Nerve
Authors: Mistry Amit , Ucer Cemal , Thompson John , Khan Rabia , Karahmet Emina , Sher Farooq
Published: September 2021

An increase in the number of implants placed has led to a corresponding increase in the number of complications reported. The complications can vary from restorative complications due to poor placement to damage to collateral structures such as nerves and adjacent teeth. A large majority of these complications can be avoided if the implant has been placed accurately in the optimal position. Therefore, the aim of this in vitro pilot study was to investigate the effect of freehand (FH) and fully guided (FG) surgery on the accuracy of implants placed in close proximity to vital structures such as the inferior alveolar nerve (IAN). Cone-beam computed tomography (CBCT) and intraoral scans of six patients who have had previous dental implants in the posterior mandible were used in this study. The ideal implant position was planned. FG surgical guides were manufactured for each case. In this study, the three-dimensional 3D printed resin models of each of the cases were produced and the implants placed using FG and FH methods on the respective models. The outcome variables of the study, angular deviations were calculated and the distance to the IAN was measured. The mean deviations for the planned position observed were 1.10 mm coronally, 1.88 mm apically with up to 6.3 degrees’ angular deviation for FH surgery. For FG surgical technique the mean deviation was found to be at 0.35 mm coronally, 0.43 mm apically with 0.78 degrees angularly respectively. The maximum deviation from the planned position for the apex of the implant to the IAN was 2.55 mm using FH and 0.63 mm FG. This bench study, within its limitations, demonstrated surgically acceptable accuracy for both FH and FG techniques that would allow safe placement of implants to vital structures such as the IAN when a safety zone of 3 mm is allowed. Nevertheless, a better margin of error was observed for FG surgery with respect to the angular deviation and controlling the distance of the implant to the IAN using R2 Gate® system.
Quantum Heat Engines with Complex Working Media, Complete Otto Cycles and Heuristics
Authors: Johal Ramandeep S. , Mehta Venu
Published: September 2021

Quantum thermal machines make use of non-classical thermodynamic resources, one of which include interactions between elements of the quantum working medium. In this paper, we examine the performance of a quasi-static quantum Otto engine based on two spins of arbitrary magnitudes subject to an external magnetic field and coupled via an isotropic Heisenberg exchange interaction. It has been shown earlier that the said interaction provides an enhancement of cycle efficiency, with an upper bound that is tighter than the Carnot efficiency. However, the necessary conditions governing engine performance and the relevant upper bound for efficiency are unknown for the general case of arbitrary spin magnitudes. By analyzing extreme case scenarios, we formulate heuristics to infer the necessary conditions for an engine with uncoupled as well as coupled spin model. These conditions lead us to a connection between performance of quantum heat engines and the notion of majorization. Furthermore, the study of complete Otto cycles inherent in the average cycle also yields interesting insights into the average performance.
On the Statistical Discrepancy and Affinity of Priority Vector Heuristics in Pairwise-Comparison-Based Methods
Authors: Kazibudzki Pawel Tadeusz
Published: September 2021

There are numerous priority deriving methods (PDMs) for pairwise-comparison-based (PCB) problems. They are often examined within the Analytic Hierarchy Process (AHP), which applies the Principal Right Eigenvalue Method (PREV) in the process of prioritizing alternatives. It is known that when decision makers (DMs) are consistent with their preferences when making evaluations concerning various decision options, all available PDMs result in the same priority vector (PV). However, when the evaluations of DMs are inconsistent and their preferences concerning alternative solutions to a particular problem are not transitive (cardinally), the outcomes are often different. This research study examines selected PDMs in relation to their ranking credibility, which is assessed by relevant statistical measures. These measures determine the approximation quality of the selected PDMs. The examined estimates refer to the inconsistency of various Pairwise Comparison Matrices (PCMs)—i.e., W = (wij), wij > 0, where i, j = 1,…, n—which are obtained during the pairwise comparison simulation process examined with the application of Wolfram’s Mathematica Software. Thus, theoretical considerations are accompanied by Monte Carlo simulations that apply various scenarios for the PCM perturbation process and are designed for hypothetical three-level AHP frameworks. The examination results show the similarities and discrepancies among the examined PDMs from the perspective of their quality, which enriches the state of knowledge about the examined PCB prioritization methodology and provides further prospective opportunities.
Future-Proofing Startups: Stress Management Principles Based on Adaptive Calibration Model and Active Inference Theory
Authors: Fox Stephen
Published: September 2021

In this paper, the Adaptive Calibration Model (ACM) and Active Inference Theory (AIT) are related to future-proofing startups. ACM encompasses the allocation of energy by the stress response system to alternative options for action, depending upon individuals’ life histories and changing external contexts. More broadly, within AIT, it is posited that humans survive by taking action to align their internal generative models with sensory inputs from external states. The first contribution of the paper is to address the need for future-proofing methods for startups by providing eight stress management principles based on ACM and AIT. Future-proofing methods are needed because, typically, nine out of ten startups do not survive. A second contribution is to relate ACM and AIT to startup life cycle stages. The third contribution is to provide practical examples that show the broader relevance ACM and AIT to organizational practice. These contributions go beyond previous literature concerned with entrepreneurial stress and organizational stress. In particular, rather than focusing on particular stressors, this paper is focused on the recalibrating/updating of startups’ stress responsivity patterns in relation to changes in the internal state of the startup and/or changes in the external state. Overall, the paper makes a contribution to relating physics of life constructs concerned with energy, action and ecological fitness to human organizations.
Entropy in Brain Networks
Authors: Poza Jesús , García María , Gomez-Pilar Javier
Published: September 2021

A thorough and comprehensive understanding of the human brain ultimately depends on knowledge of large-scale brain organization[...]
An Ontology-Based Framework for a Telehealthcare System to Foster Healthy Nutrition and Active Lifestyle in Older Adults
Authors: Spoladore Daniele , Colombo Vera , Arlati Sara , Mahroo Atieh , Trombetta Alberto , Sacco Marco
Published: September 2021

In recent years, telehealthcare systems (TSs) have become more and more widespread, as they can contribute to promoting the continuity of care and managing chronic conditions efficiently. Most TSs and nutrition recommendation systems require much information to return appropriate suggestions. This work proposes an ontology-based TS, namely HeNuALs, aimed at fostering a healthy diet and an active lifestyle in older adults with chronic pathologies. The system is built on the formalization of users’ health conditions, which can be obtained by leveraging existing standards. This allows for modeling different pathologies via reusable knowledge, thus limiting the amount of information needed to retrieve nutritional indications from the system. HeNuALs is composed of (1) an ontological layer that stores patients and their data, food and its characteristics, and physical activity-related data, enabling the inference a series of suggestions based on the effects of foods and exercises on specific health conditions; (2) two applications that allow both the patient and the clinicians to access the data (with different permissions) stored in the ontological layer; and (3) a series of wearable sensors that can be used to monitor physical exercise (provided by the patient application) and to ensure patients’ safety. HeNuALs inferences have been validated considering two different use cases. The system revealed the ability to determine suggestions for healthy, adequate, or unhealthy dishes for a patient with respiratory disease and for a patient with diabetes mellitus. Future work foresees the extension of the HeNuALs knowledge base by exploiting automatic knowledge retrieval approaches and validation of the whole system with target users.
A Survey on Adversarial Deep Learning Robustness in Medical Image Analysis
Authors: Apostolidis Kyriakos D. , Papakostas George A.
Published: September 2021

In the past years, deep neural networks (DNN) have become popular in many disciplines such as computer vision (CV), natural language processing (NLP), etc. The evolution of hardware has helped researchers to develop many powerful Deep Learning (DL) models to face numerous challenging problems. One of the most important challenges in the CV area is Medical Image Analysis in which DL models process medical images—such as magnetic resonance imaging (MRI), X-ray, computed tomography (CT), etc.—using convolutional neural networks (CNN) for diagnosis or detection of several diseases. The proper function of these models can significantly upgrade the health systems. However, recent studies have shown that CNN models are vulnerable under adversarial attacks with imperceptible perturbations. In this paper, we summarize existing methods for adversarial attacks, detections and defenses on medical imaging. Finally, we show that many attacks, which are undetectable by the human eye, can degrade the performance of the models, significantly. Nevertheless, some effective defense and attack detection methods keep the models safe to an extent. We end with a discussion on the current state-of-the-art and future challenges.
A Novel TDoA-Based Method for 3D Combined Localization Techniques Using an Ultra-Wideband Phase Wrapping-Impaired Switched Beam Antenna
Authors: Passafiume Marco , Collodi Giovanni , Ciervo Edoardo , Cidronali Alessandro
Published: September 2021

This paper presents a novel Time Difference of Arrival-based approach suitable for single-anchor positioning systems, implemented by phase wrapping-impaired array antenna. With the latter being a typical occurrence in large Switched Beam Antenna (SBA) operating in the low microwave range. The proposed method takes advantage from the large bandwidth of radio link, established between the anchor and the positioning target, by generating an unambiguous equivalent phase relationship between antenna array elements. The technique is validated by adopting a relatively large SBA antenna operating in the 4.75–6.25 GHz bandwidth, and capable to position a target in a 3D domain. Experimental data, carried out in the 4–7 GHz frequency bandwidth, show that by dealing properly with the inherent constraint of phase wrapping issues, it is possible to get a significant improvement on the elevation angle with respect to methods not capable to deal with phase reconstruction and thus operating in a phase-less context. Combining range and angle errors, the associated cumulative distribution function error in 90% of cases shows an error of 0.13 m.
Breaking the Dichotomies: Climate, Coal, and Gender. Paving the Way to a Just Transition. The Example of Colombia
Authors: Mohr Kerstin
Published: September 2021

Despite recognizing that climate change and its impacts are not gender-neutral, only few studies address the arising complexities. While in some climate-relevant sectors, such as the transport sector, there already is some initial research on the relationship between climate and gender, research on the climate–gender nexus in the coal sector is still underdeveloped, and the few existing studies focus on dichotomous relations (gender–coal and coal–climate). This article discusses the currently neglected climate, coal, and gender triad and develops a conceptualization along the following aspects: (i) common lines of arguments, (ii) shortcomings in predominant arguments, and (iii) the state-of-the-art regarding the climate–gender–coal triad. To illustrate this outline, it uses the empirical case of the Colombian coal sector. Based on original data obtained via semi-structured interviews, it analyzes how imminent national-level climate policies for the coal sector, i.e., an energy transition, can be made gender-responsive and thus contribute to a just transition. The empirical example shows that women are already important change agents at the local level and in informal decision-making spaces. Although more research is needed to obtain further insights and evidence, this article contributes to the findings of more recent research which allow for the assumption that addressing climate and gender simultaneously may be mutually beneficial for both policy objectives.
Projection of Post-Pandemic Italian Industrial Production through Vector AutoRegressive Models
Authors: Oliva Antonio , Gracceva Francesco , Lerede Daniele , Nicoli Matteo , Savoldi Laura
Published: September 2021

Energy system models for the analysis of future scenarios are mainly driven by the set of energy service demands that define the broad outlines of socio-economic development throughout the model time horizon. Here, the long-term effects of the COVID-19 pandemic on the drivers of the industrial production in six energy-intensive subsectors are addressed using Vector AutoRegressive models. The model results are computed either considering or not considering the effects of the pandemic. The comparison to established pre-pandemic trends allows for validating the robustness of the selected model. The anticipated effect of the pandemic to 2040 shows a long-term reduction by 3% to 10%, according to the different subsector, in the industrial energy service demand. When the computed service demands are used as input to the TIMES-Italy model, which shows good capability to reproduce the energy consumption of the industrial sectors in the period 2006–2020, the impact of the pandemic on energy consumption forecasts can be assessed in a business-as-usual scenario. The results show how the long-term effects of the shock caused by the pandemic could lead, by 2040, to a total industrial energy consumption 5% lower than what was foreseen before the pandemic, while the energy mix remains almost unchanged.
Review of Energy Management System Approaches in Microgrids
Authors: Battula Amrutha Raju , Vuddanti Sandeep , Salkuti Surender Reddy
Published: September 2021

To sustain the complexity of growing demand, the conventional grid (CG) is incorporated with communication technology like advanced metering with sensors, demand response (DR), energy storage systems (ESS), and inclusion of electric vehicles (EV). In order to maintain local area energy balance and reliability, microgrids (MG) are proposed. Microgrids are low or medium voltage distribution systems with a resilient operation, that control the exchange of power between the main grid, locally distributed generators (DGs), and consumers using intelligent energy management techniques. This paper gives a brief introduction to microgrids, their operations, and further, a review of different energy management approaches. In a microgrid control strategy, an energy management system (EMS) is the key component to maintain the balance between energy resources (CG, DG, ESS, and EVs) and loads available while contributing the profit to utility. This article classifies the methodologies used for EMS based on the structure, control, and technique used. The untapped areas which have scope for investigation are also mentioned.
Edge HVAC Analytics
Authors: Petri Ioan , Rana Omer , Rezgui Yacine , Fadli Fodil
Published: September 2021

Integrating data analytics, optimisation and dynamic control to support energy services has seen significant interest in recent years. Larger appliances used in an industry context are now provided with Internet of Things (IoT)-based interfaces that can be remotely monitored, with some also provided with actuation interfaces. The combined use of IoT and edge computing enables connectivity between energy systems and infrastructure, providing the means to implement both energy efficiency/optimisation and cost reduction strategies. We investigate the economic implications of harnessing IoT and edge/cloud technologies to support energy management for HVAC (Heating, Ventilation and Air Conditioning) systems in buildings. In particular, we evaluate the cost savings for building operations through energy optimisation. We use a real use case for energy optimisation as identified in the EU “Sporte2” project (focusing on the energy optimisation of sports facilities) and explore several scenarios in relation to costs and energy optimisation.
Application of ORC in a Distributed Integrated Energy System Driven by Deep and Shallow Geothermal Energy
Authors: Yin Hongmei , Hu Likai , Li Yang , Gong Yulie , Du Yanping , Song Chaofan , Zhao Jun
Published: September 2021

This study presents a distributed integrated energy system driven by deep and shallow geothermal energy based on forward and reverse cycle for flexible generation of cold, heat and electricity in different scenarios. By adjusting the strategy, the system can meet the demand of heat-electricity in winter, cool-electricity in summer and electricity in transition seasons. The thermodynamic analysis shows that the thermal efficiency of the integrated energy system in the heating and power generation mode is 16% higher than that in the cooling and power generation mode or the single power generation mode. Meanwhile, the annual heat-obtaining quantity of the system is reduced by 11% compared with that of the independent power generation system, which effectively alleviates the imbalance of the temperature field of the shallow geothermal reservoir. In terms of net power generation, the integrated energy system can generate approximately 31% more electricity than the conventional independent cooling and heating system under the same cooling and heating capacity. An integrated system not only realizes the comprehensive supply of cold and thermal ower by using clean geothermal efficiency, but also solves the temperature imbalance caused by the attenuation of a shallow geothermal temperature field. It provides a feasible way for carbon emission reduction to realize sustainable and efficient utilization of geothermal energy.
Integrated, Multi-Approach, Adaptive Control of Two-Mass Drive with Nonlinear Damping and Stiffness
Authors: Kabziński Jacek , Mosiołek Przemysław
Published: September 2021

In numerous electric drive applications, the mechanical phenomena in the velocity or position control loop determine real difficulties and challenges for the control system. So-called two-mass drive systems with a flexible shaft are the most important example of this situation. The problem becomes even more difficult if the characteristics of torque transmission along the shaft are nonlinear, nonlinear friction is present, and the plant parameters are unknown, as it happens in numerous robotic systems. A novel adaptive controller is derived for such a system. The recurrent design procedure is based on proper modifications of the adaptive backstepping scheme, including non-strict-feedback plant application, tuning functions to exclude controller overparameterization, robust adaptive laws, proper means to avoid controller complexity explosion, and a nonlinear PI controller in the initial loop to minimize quasi-steady-state tracking error. The closed-loop system uniform ultimate boundedness is proven using Lyapunov techniques and the design and tuning procedures are described. The attractive features of the obtained drive, including the robustness against the violation of assumptions, are presented using several examples.
Time-Lapse Integration at FWU: Fluids, Rock Physics, Numerical Model Integration, and Field Data Comparison
Authors: Will Robert , Bratton Tom , Ampomah William , Acheampong Samuel , Cather Martha , Balch Robert
Published: September 2021

We present the current status of time-lapse seismic integration at the Farnsworth (FWU) CO2 WAG (water-alternating-gas) EOR (Enhanced Oil Recovery) project at Ochiltree County, northwest Texas. As a potential carbon sequestration mechanism, CO2 WAG projects will be subject to some degree of monitoring and verification, either as a regulatory requirement or to qualify for economic incentives. In order to evaluate the viability of time-lapse seismic as a monitoring method the Southwest Partnership (SWP) has conducted time-lapse seismic monitoring at FWU using the 3D Vertical Seismic Profiling (VSP) method. The efficacy of seismic time-lapse depends on a number of key factors, which vary widely from one application to another. Most important among these are the thermophysical properties of the original fluid in place and the displacing fluid, followed by the petrophysical properties of the rock matrix, which together determine the effective elastic properties of the rock fluid system. We present systematic analysis of fluid thermodynamics and resulting thermophysical properties, petrophysics and rock frame elastic properties, and elastic property modeling through fluid substitution using data collected at FWU. These analyses will be framed in realistic scenarios presented by the FWU CO2 WAG development. The resulting fluid/rock physics models will be applied to output from the calibrated FWU compositional reservoir simulation model to forward model the time-lapse seismic response. Modeled results are compared with field time-lapse seismic measurements and strategies for numerical model feedback/update are discussed. While mechanical effects are neglected in the work presented here, complementary parallel studies are underway in which laboratory measurements are introduced to introduce stress dependence of matrix elastic moduli.
Applying Solar PV to Heat Pump and Storage Technologies in Australian Houses
Authors: Simko Tom , Luther Mark B. , Li Hong Xian , Horan Peter
Published: September 2021

Innovative mechanical services coupled with renewable energy systems are crucial for achieving a net zero energy goal for houses. Conventional systems tend to be vastly oversized because they lack the means to buffer energy flows and are based on peak loads. This paper presents an approach to achieve a net zero energy goal for houses by using a solar PV system, heat pumps, and thermal and electrical storage batteries, all off-the-shelf. Constraining one part of the system and then showing how to manage energy storage and flow is a paradigm shift in sizing. The design is for a modest-sized house built in Melbourne, Australia. The output of a solar photovoltaic array drives a small-scale heat pump to heat water, buffering its energy in a thermal battery to energise a radiant space heating system. Space cooling is provided by a separate heat pump. Through energy storage in electrical and thermal batteries, it is possible to meet the electricity, heating and cooling needs of the house for the Melbourne climate with a heat pump that draws less than 1 kW. The design methodology is detailed in an appendix and can be applied to similar projects. This paper contributes to similar work worldwide that aims to reinforce innovative renewable energy driven service design.
Numerical Analysis of Mixed Convective Heat Transfer from a Square Cylinder Utilizing Nanofluids with Multi-Phase Modelling Approach
Authors: Rajpoot Rajendra S. , Dhinakaran Shanmugam. , Alam Md. Mahbub
Published: September 2021

The present study deals with the numerical simulation of mixed convective heat transfer from an unconfined heated square cylinder using nanofluids (Al2O3-water) for Reynolds number (Re) 10–150, Richardson number (Ri) 0–1, and nanoparticles volume fractions (φ) 0–5%. Two-phase modelling approach (i.e., Eulerian-mixture model) is adopted to analyze the flow and heat transfer characteristics of nanofluids. A square cylinder with a constant temperature higher than that of the ambient is exposed to a uniform flow. The governing equations are discretized and solved by using a finite volume method employing the SIMPLE algorithm for pressure–velocity coupling. The thermo-physical properties of nanofluids are calculated from the theoretical models using a single-phase approach. The flow and heat transfer characteristics of nanofluids are studied for considered parameters and compared with those of the base fluid. The temperature field and flow structure around the square cylinder are visualized and compared for single and multi-phase approaches. The thermal performance under thermal buoyancy conditions for both steady and unsteady flow regimes is presented. Minor variations in flow and thermal characteristics are observed between the two approaches for the range of nanoparticle volume fractions considered. Variation in φ affects CD when Reynolds number is varied from 10 to 50. Beyond Reynolds number 50, no significant change in CD is observed with change in φ. The local and mean Nusselt numbers increase with Reynolds number, Richardson number, and nanoparticle volume fraction. For instance, the mean Nusselt number of nanofluids at Re = 100, φ = 5%, and Ri = 1 is approximately 12.4% higher than that of the base fluid. Overall, the thermal enhancement ratio increases with φ and decreases with Re regardless of Ri variation.
Amanita muscaria: Ecology, Chemistry, Myths
Authors: Carboué Quentin , Lopez Michel
Published: September 2021

Amanita muscaria is the most emblematic mushroom in the popular representation. It is an ectomycorrhizal fungus endemic to the cold ecosystems of the northern hemisphere. The basidiocarp contains isoxazoles compounds that have specific actions on the central nervous system, including hallucinations. For this reason, it is considered an important entheogenic mushroom in different cultures whose remnants are still visible in some modern-day European traditions. In Siberian civilizations, it has been consumed for religious and recreational purposes for millennia, as it was the only inebriant in this region.
Sustainable Extraction Techniques for Obtaining Antioxidant and Anti-Inflammatory Compounds from the Lamiaceae and Asteraceae Species
Authors: Villalva Marisol , Santoyo Susana , Salas-Pérez Lilia , Siles-Sánchez María de las Nieves , Rodríguez García-Risco Mónica , Fornari Tiziana , Reglero Guillermo , Jaime Laura
Published: September 2021

Melissa officinalis L. and Origanum majorana L., within Lamiaceae family, and Calendula officinalis L. and Achillea millefolium L., within the Asteraceae, have been considered a good source of bioactive ingredients with health benefits. In this study, the supercritical fluid extraction (SFE) using pure CO2, and the ultrasound assisted extraction (UAE) were proposed as green techniques to obtain plant-based extracts with potential antioxidant and anti-inflammatory activities. Higher values of total phenolic content and antioxidant activity were achieved in UAE ethanol:water (50:50, v/v) extracts. Meanwhile, UAE pure ethanol extracts showed greater anti-inflammatory activity. RP-HPLC-PAD-ESI-QTOF-MS/MS analysis showed a vast number of phenolic compounds in the extracts, including unreported ones. O. majorana ethanol:water extract presented the highest content of phenolics and antioxidant activity; among its composition, both rosmarinic acid and luteolin glucoside derivatives were abundant. The pure ethanol extract of A. millefolium resulted in an important content of caffeoylquinic acid derivatives, luteolin-7-O-glucoside and flavonoid aglycones, which could be related to the remarkable inhibition of TNF-α, IL-1β and IL-6 cytokines. Besides, borneol and camphor, found in the volatile fraction of A. millefolium, could contributed to this latter activity. Thus, this study points out that O. majorana and A. millefolium are considered a promising source of bioactive ingredients with potential use in health promotion.
Food Innovation as a Means of Developing Healthier and More Sustainable Foods
Authors: Rabadán Adrián , Nieto Roberto , Bernabéu Rodolfo
Published: September 2021

The current demand for healthy and sustainable foods has encouraged the development of new alternatives even in traditional products. Improved foods may be produced by reducing the amount of some ingredients, adding new ones, or replacing traditionally used ingredients for others. By reformulating their products, manufacturers can offer healthier choices for an ever-growing number of consumers interested in maintaining a balanced diet. In addition, the market demand for more sustainable foods contributes to a lower environmental impact in their production. In this regard, current areas of interest include the production of foods using a lower number of inputs, as well as the utilization of food by-products, to improve the amount and quality of available foods. Another aspect to be considered is that not all consumers are willing to eat foods produced with new ingredients or novel technologies. Hence, the development of innovations in food products should take into account the influence of so-called “consumer food neophobia”.
Survival of Escherichia coli and Listeria innocua on Lettuce after Irrigation with Contaminated Water in a Temperate Climate
Authors: Machado-Moreira Bernardino , Richards Karl , Abram Florence , Brennan Fiona , Gaffney Michael , Burgess Catherine M.
Published: September 2021

Microbial disease outbreaks related to fresh produce consumption, including leafy green vegetables, have increased in recent years. Where contamination occurs, pathogen persistence may represent a risk for consumers’ health. This study analysed the survival of E. coli and L. innocua on lettuce plants watered with contaminated irrigation water via a single irrigation event and within stored irrigation water. Separate lettuce plants (Lactuca sativa var. capitata) were irrigated with water spiked with Log10 7 cfu/mL of each of the two strains and survival assessed via direct enumeration, enrichment and qPCR. In parallel, individual 20 L water microcosms were spiked with Log10 7 cfu/mL of the individual strains and sampled at similar time points. Both strains were observed to survive on lettuce plants up to 28 days after inoculation. Direct quantification by culture methods showed a Log10 4 decrease in the concentration of E. coli 14 days after inoculation, and a Log10 3 decrease in the concentration of L. innocua 10 days after inoculation. E. coli was detected in water samples up to 7 days after inoculation and L. innocua was detected up to 28 days by direct enumeration. Both strains were recovered from enriched samples up to 28 days after inoculation. These results demonstrate that E. coli and L. innocua strains are able to persist on lettuce after a single contamination event up until the plants reach a harvestable state. Furthermore, the persistence of E. coli and L. innocua in water for up to 28 days after inoculation illustrates the potential for multiple plant contamination events from stored irrigation water, emphasising the importance of ensuring that irrigation water is of a high quality.
High-Frequency Focused Ultrasound on Quality Traits of Bovine Triceps brachii Muscle
Authors: Caraveo-Suarez Reyes Omaro , Garcia-Galicia Ivan Adrian , Santellano-Estrada Eduardo , Carrillo-Lopez Luis Manuel , Huerta-Jimenez Mariana , Vargas-Bello-Pérez Einar , Alarcon-Rojo Alma Delia
Published: September 2021

This aim of this study was to evaluate the effect of high-frequency focused ultrasound (HFFU) on quality traits of bovine Triceps brachii. Four treatments (0, 10, 20, and 30 min) of HFFU (2 MHz and 1.5 W/cm2) were applied to bovine T. brachii muscle. Immediately after treatment, evaluations of color, pH, drip loss, water holding capacity, and shear force in meat were undertaken. The application of HFFU slightly decreased (p < 0.05) the redness of meat. In addition, a significant (p < 0.05) decrease in the shear force of meat was observed after the application of HFFU at 30 min. No effect (p > 0.05) was observed on other color parameters, drip loss, and water holding capacity of meat. Overall, HFFU improved beef tenderness without negative impacts on color, pH, drip loss, and water holding capacity of meat. HFFU offers the option of tenderizing specific muscles or anatomical regions of the beef carcass. These findings provide new insights into the potential application of ultrasound in meat processing.
Key Factors Affecting the Flesh Flavor Quality and the Nutritional Value of Grass Carp in Four Culture Modes
Authors: Zhang Junming , Kaneko Gen , Sun Jinhui , Wang Guangjun , Xie Jun , Tian Jingjing , Li Zhifei , Gong Wangbao , Zhang Kai , Xia Yun , Yu Ermeng
Published: September 2021

Flavor and nutritional value are important qualities of freshwater fish products, but the key factors affecting these quality parameters remain unclear. In this study, four typical aquaculture modes, including the commercial feed treatment (control), faba bean treatment (FBT), grass powder treatment (GPT), and waving water treatment with commercial feed (WWT), were used to explore the regulatory effect of water quality and feed (eaten and uneaten) on the flesh flavor and nutrition in grass carp (Ctenopharyngodon idella), a freshwater fish of the largest global production. During the culture period (90 days), water quality parameters of the four modes were measured every 15 days, and the flavor quality was evaluated by volatile flavor compounds detection and electronic nose analyzer. Flesh crude protein, crude fat, free fatty acid and free amino acid profiles were also determined. The results showed that, in the late period, the FBT mode had the poorest water quality with highest concentrations of nitrite and nitrate, while the GPT mode has the best water quality among the four modes. Most flesh flavor compounds found in the flesh of the control, GPT and WWT modes were pleasant. In the FBT mode with the poorest water quality, on the other hand, we found lower flavor quality (higher contribution of fishy compounds), higher water content, and lower contents of crude protein, crude fat, free fatty acids and free amino acids, compared to the other three modes. Correlation analyses showed that nitrite and nitrate are probably key water quality factors affecting the flavor quality and nutritional values besides eaten feed and uneaten feed factors. This study can serve as an important reference for ecological regulation and feeding administration of flesh quality in freshwater aquaculture fish.
Locally-Procured Fish Is Essential in School Feeding Programmes in Sub-Saharan Africa
Authors: Ahern Molly B. , Thilsted Shakuntala Haraksingh , Kjellevold Marian , Overå Ragnhild , Toppe Jogeir , Doura Michele , Kalaluka Edna , Wismen Bendula , Vargas Melisa , Franz Nicole
Published: September 2021

Fish make an important contribution to micronutrient intake, long-chained polyunsaturated omega-3 fatty acids (n-3 LC-PUFAS), and animal protein, as well as ensuring food and nutrition security and livelihoods for fishing communities. Micronutrient deficiencies are persistent in sub-Saharan Africa (SSA), contributing to public health issues not only in the first 1000 days but throughout adolescence and into adulthood. School feeding programs (SFPs) and home-grown school feeding programs (HGSF), which source foods from local producers, particularly fisherfolk, offer an entry point for encouraging healthy diets and delivering essential macro- and micronutrients to schoolchildren, which are important for the continued cognitive development of children and adolescents and can contribute to the realization of sustainable development goals (SDGs) 1, 2, 3, 5, and 14. The importance of HGSF for poverty alleviation (SDG1) and zero hunger (SDG 2) have been recognized by the United Nations Hunger Task Force and the African Union Development Agency–New Partnership for African Development (AUDA-NEPAD), which formulated a strategy for HGSF to improve nutrition for the growing youth population across Africa. A scoping review was conducted to understand the lessons learned from SFPs, which included fish and fish products from small-scale producers, identifying the challenges and best practices for the inclusion of fish, opportunities for improvements across the supply chain, and gaps in nutritional requirements for schoolchildren which could be improved through the inclusion of fish. Challenges to the inclusion fish in SFPs include food safety, supply and access to raw materials, organizational capacity, and cost, while good practices include the engagement of various stakeholders in creating and testing fish products, and repurposing fisheries by-products or using underutilized species to ensure cost-effective solutions. This study builds evidence of the inclusion of nutritious fish and fish products in SFPs, highlighting the need to replicate and scale good practices to ensure sustainable, community-centred, and demand-driven solutions for alleviating poverty, malnutrition, and contributing to greater health and wellbeing in adolescence.
Accessibility Indicators for the Geographical Assessment of Transport Planning in a Latin American Metropolitan Area
Authors: Martínez Marcela , Rojas Carolina , Condeço-Melhorado Ana , Carrasco Juan Antonio
Published: September 2021

Accessibility represents a key element in strengthening developed regions in terms of investment in transportation infrastructure. Accessibility is also an equity indicator to measure the ease with which a specific location achieves desired outcomes as well as the spillover effect; traditionally, these effects have been analyzed with econometric and engineering techniques, rather than from the perspective of geographical studies. The purpose of this research is to measure the spillover effects and the territorial cohesion of Infrastructure Regional Planning (PRI) for the Latin American metropolitan area of Concepción (MAC), Chile. To meet this purpose, locational and network efficiency indicators of spatial accessibility were calculated using network analysis in GIS. The results showed that the improvements differ according to the accessibility indicator employed; however, they generally showed benefits in consolidated urban centers and corridors near investment and industrial areas. In contrast, more distant and rural areas presented limited and irregular benefits.
COVID-19 Disease Leading to Chronic Spontaneous Urticaria Exacerbation: A Romanian Retrospective Study
Authors: Muntean Ioana Adriana , Pintea Irena , Bocsan Ioana Corina , Dobrican Carmen Teodora , Deleanu Diana
Published: September 2021

(1) Background: The COVID-19 pandemic has resulted in the exacerbation of various chronic diseases. Due to the potential impact of SARS-CoV-2 on mast cells, we aimed to analyze the relevance of COVID-19 disease on chronic spontaneous urticaria (CSU) clinical presentation and biological profile. (2) Methods: This study is a retrospective case series of patients with CSU diagnosed and treated in the Allergy Department of the Professor Doctor Octavian Fodor RIGH, (Cluj-Napoca, Romania). Patients were assessed for disease activity and level of control with the weekly urticaria activity score and the visual analogue scale. Results were correlated with COVID-19 severity and with nonspecific markers of inflammation during and after the SARS-CoV-2 infection. (3) Results: SARS-CoV-2 impacted a significant proportion (33%) of the CSU patients, of which 71% developed a moderate-severe form of COVID-19. Most of the patients (68%) had moderate-severe forms of CSU and 65% took AH1 treatment (one dose, two-fold dose or four-fold dose). The rest of them (35%) received the second-line treatment (40.3% Omalizumab, 53% Prednisolone and 4.8% Cyclosporine). In Omalizumab treated group of UCS patients we observed that COVID-19 disease was not severe. We established a positive correlation between the severity of the infection and that of the CSU clinical presentation, with most bothersome symptoms of urticaria being experienced by moderate to severe COVID-19 CSU patients (47%). Inflammatory markers were positively correlated (p = 0.01) with a more severe clinical profile of CSU, in accordance with our hypothesis that the level of inflammation triggered by COVID-19 disease has a role in CSU exacerbation. The non-specific inflammatory markers, such as CRP, were positively associated with the UAS7 score (R2 = 0.363; p = 0.001). An increased rate of exacerbation of CSU was observed in moderate-severe COVID-19 infection. (4) Conclusions: COVID-19 disease can result in the exacerbation of chronic spontaneous urticaria, more likely in moderate to severe forms of infection.
Influence of Nordic Walking Training on Vitamin D Level in the Blood and Quality of Life among Women Aged 65–74
Authors: Podsiadło Szymon , Skiba Agnieszka , Kałuża Anna , Ptaszek Bartłomiej , Stożek Joanna , Skiba Amadeusz , Marchewka Anna
Published: September 2021

Introduction. Demographic forecasts indicate the progressive aging process of societies in all countries worldwide. The extension of life span may be accompanied by deterioration of its quality resulting from a decrease in physical activity, mental or even social performance, and a deficit in certain chemical compounds responsible for proper functioning of the body. Aim. The aim of the study was to evaluate the influence of a 12-week Nordic walking (NW) training intervention on the level of vitamin D in the blood and quality of life among women aged 65–74 years. Materials and methods. The study comprised 37 women aged 65–74 (x = 68.08, SD = 4.2). The subjects were randomly assigned to 2 groups: experimental group (NW), which consisted of 20 women who underwent an intervention in the form of Nordic walking training for 12 weeks, and the control group (C), including 17 women who underwent observation. In the experimental group, training sessions were held 3 times a week for 1 h. At that time, the C group was not subject to any intervention. The SF−36 questionnaire was used to measure quality of life. Vitamin D was assessed based on the results of biochemical blood tests. The analysed parameters were assessed twice-before and after the completed intervention or observation. Results. Comparison of the results regarding trials 1 and 2 allowed to note statistically significant improvement in quality of life for all health components and factors in the NW group. Analysis of vitamin D levels demonstrated a statistically significant increase in the NW group. In group C, no significant changes in the analysed parameters were observed. Conclusions. Regularly undertaking Nordic walking training significantly influences the improvement of self-evaluation regarding the components of physical and mental health, as well as the concentration of vitamin D in women aged 65–74 years.
Predicting Emotional Valence of People Living with the Human Immunodeficiency Virus Using Daily Voice Clips: A Preliminary Study
Authors: Lin Ray F. , Cheng Shu-Hsing , Liu Yung-Ping , Chen Cheng-Pin , Wang Yi-Jyun , Chang Shu-Ying
Published: September 2021

To detect depression in people living with the human immunodeficiency virus (PLHIV), this preliminary study developed an artificial intelligence (AI) model aimed at discriminating the emotional valence of PLHIV. Sixteen PLHIV recruited from the Taoyuan General Hospital, Ministry of Health and Welfare, participated in this study from 2019 to 2020. A self-developed mobile application (app) was installed on sixteen participants’ mobile phones and recorded their daily voice clips and emotional valence values. After data preprocessing of the collected voice clips was conducted, an open-source software, openSMILE, was applied to extract 384 voice features. These features were then tested with statistical methods to screen critical modeling features. Several decision-tree models were built based on various data combinations to test the effectiveness of feature selection methods. The developed model performed very well for individuals who reported an adequate amount of data with widely distributed valence values. The effectiveness of feature selection methods, limitations of collected data, and future research were discussed.