bluuebunny/crossref_metadata_2025 huggingface dataset:
Творчо-педагогічні аспекти формування інноваційної компетентності майбутніх учителів мистецтва
Authors: Барановська Ірина , Коваль Тетяна , Якименко Юлія
Published: December 2024

The article raises the question of a competence-oriented approach to the professional training of future art teachers. The analysis of normative educational documents, scientific work of modern domestic and foreign scientists in the field of art pedagogy on the problem of research was carried out. The essence of the phenomena of «innovation», «professional competence», «innovative competence of the art teacher» is characterized. It was found that the concept of «innovation» is considered as an effective tool and leading mechanism of development. Innovations in education lead to overcoming crisis phenomena, are associated with the generation of new ideas, improvement of methods, technologies of education and upbringing, contribute to its development. Professional competence is considered "as a personified property that characterizes the teacher's pedagogical skills and his ability to innovate. It was determined that professional skill is the result of education and self-development, it is an indicator of pedagogical experience, artistic erudition and awareness, formed individual abilities and abilities of the teacher. The innovative competence of a modern art teacher is characterized as an integral construct based on awareness of the value and familiarity with traditional and innovative art-pedagogical technologies; the formed motivational professional worldview position of the teacher-artist; striving to acquaint students with the cultural picture of the world by revealing the codes of artistic and figurative language of works of art by means of innovative artistic technologies; innovative orientation, broad artistic erudition, communicative tolerance, ability to reflect. The results of an experiment to study the motivation of applicants to use innovative technologies while performing creative tasks are presented. It has been proven that the development and inclusion in the content of selective disciplines of the artistic direction of creative integrated tasks that require knowledge of the methodology of applying innovative technologies is effective and justified. The issue of substantiating pedagogical conditions for the formation of innovative competence of future art teachers in the process of pedagogical practice requires further research.
Інноваційні методи, технології та моніторинг якості електронного навчання (Лабораторний практикум): навчальний посібник
Authors:   Vinnytsia Mykhailo Kotsiubynskyi State Pedagogical University, Шахіна Ірина
Published: December 2024

У навчальному посібнику основна увага приділена висвітленню матеріалів для проведення лабораторних робіт із дисципліни «Інноваційні методи, технології та моніторинг якості електронного навчання» для магістрів галузі знань 01 Освіта / Педагогіка за спеціальністю 015.39 Професійна освіта (Цифрові технології). Зміст посібника охоплює
питання використання інноваційних технологій, а саме інформаційно-комунікаційних, інтерактивних та проектних технологій в освітньому процесі cучасного фахівця, а також тестових технологій моніторингу та контролю знань електронного навчання (обробки результатів тестування, показників якості тестових завдань, оцінки вірогідностей відповіді,
методик для визначення надійності та валідності тестів, кількісних показників). У посібнику також наведено структуру навчальної дисципліни, розподіл навчального часу, тематичний план, вимоги щодо рівня знань і вмінь, критерії оцінювання знань студентів, розподіл балів,
які отримують студенти, завдання для самостійного опрацювання, питання для підсумкового контролю знань студентів, додатки, тести для проведення незалежного моніторингу знань, глосарій, список джерел для вивчення дисципліни, ресурси Інтернет.
Використані інноваційні методи навчання сприятимуть розвитку творчої особистості студентів, допоможуть закріпити, поглибити та cистематизувати знання, одержані під час занять з предмету «Інноваційні методи, технології та моніторинг якості електронного навчання».
Навчальний посібник буде корисним студентам педагогічних закладів освіти. Стане в пригоді викладачам ЗВО, вчителям ЗЗСО, ЗПТО, методистам, магістрантам, аспірантам, докторантам.
Історія мистецтв у контексті світової культури Т.3
Authors:   Vinnytsia Mykhailo Kotsiubynskyi State Pedagogical University, Москвічова Юлія
Published: December 2024

Навчально-методичний посібник містить широкий комплекс матеріалів курсу “Історія мистецтв” для студентів закладів вищої освіти України; охоплює детальний виклад лекційно-теоретичного масиву, використану та рекомендовану літературу, контрольні запитання та тестові завдання для самоперевірки студентів, широкий ілюстративний матеріал, інформативний глосарій, теми для індивідуальних навчально-дослідних завдань. У посібнику розкрито зміст всіх історичних періодів розвитку провідних культурних регіонів світу, що включає характеристику найважливіших здобутків у літературі, архітектурі, образотворчому мистецтві, освіті, театрі тощо. Основна увага зосереджена на знакових історичних постатях і видатних діячах мистецтва різних країн світу, світоглядних уявленнях та стильових характеристиках кожної конкретної епохи.
Tailored Flood Risk Communication
Authors: Snel Karin A. W. , Priest Sally , Hartmann Thomas , Witte Patrick A. , Geertman Stan C. M.
Published: December 2024

Flood risk is increasing, and residents are expected to undertake adaptation measures to minimize flood damage. This requires them to be aware of the risk they face and how they can adapt, but this is often not the case. Through risk communication, residents’ relation to their flood-prone environment could be strengthened, but the effect remains limited. This article aims to understand how residents across countries prefer flood risk communication and provides a basis for developing communication strategies that manage to raise awareness on risk and adaptation. Residents living in flood risk areas in England and the Netherlands were interviewed on their preferences for flood risk communication. The Q-methodology, consisting of 34 Q-sorts, resulted in four significantly different sets of preferences: (1) localist; (2) sufficientist; (3) imperfectionist; and (4) conventionalist. Moreover, cultural and individual factors, such as country of residence, flood experience, and responsibility division, prove potential determiners for these distinctly different perspectives.
Examining the Role of Teachers' Professionalism in Mitigating Aggressive Behavior among University-Level Resilient Students
Authors: Zaman Muhammad Shokat , Iqbal Muhammad Nadeem , Saleem Khalid
Published: December 2024

The study focused on investigating the role of teachers' professionalism in mitigating aggressive behavior among university-level resilient students. The quantitative survey design was followed to conduct this study. The study sample consisted of 237 students with MPhil and PhD degrees (Edu). Three tools (The Brief Resilience Scale, the Aggression Questionnaire, and the Teachers Professionalism Scale) were used in this quantitative study to collect data. Tools were converted to Google Forms and disseminated for data collection. Data were analyzed by utilizing descriptive (percentage, mean, standard deviation) and inferential statistics (Pearson correlation, and Hays Process macro mediation analysis model-4). Results revealed that university students were normally resilient and, there was a significant moderating role of the resilience of students on the relationship between teachers' professionalism and the aggressive behavior of students. The study indicates that university teachers necessitate more interventions to enhance the resilience of graduate students and decrease the level of aggression.
Maternal factors associated with low birth weight among new-borns delivered in selected government hospitals in Kalutara district
Authors:   Faculty of Medicine, University of Moratuwa, Sri Lanka, Herath H.M.S.N. , Hasanga P.K.D.T. , Haneeka M.H.F. , Hettiarachchi B.R.N.R. , Hewage T.K. , Samarasinghe S. ,   Department of Physiology, Faculty of Medicine, University of Moratuwa, Siriwardene I.D. ,   Department of Biochemistry and Clinical Chemistry, Faculty of Medicine, University of Moratuwa
Published: December 2024

Low Birth Weight (LBW) is a major global public health concern, with profound implications on neonatal morbidity and mortality. Understanding the factors associated with LBW is crucial for effective interventions. Hence, this study was conducted to assess the maternal factors associated with low birth weight among newborns delivered in selected government hospitals in Kalutara District.
Proportion of undernutrition and its associated factors among preschoolers in Wadduwa MOH area of Kalutara district
Authors:   Faculty of Medicine, University of Moratuwa, Sri Lanka, Dunanja W.W.R. , Dassanayake N.S.S. , Dilakshika B.G.D. , De Seram H.G.S.T. , Dulanjana W.M.M. , Paranavithana S.S. ,   Department of Biochemistry and Clinical Chemistry, Faculty of Medicine, University of Moratuwa, Uluwaduge D.I. ,   Department of Basic Sciences, Faculty of Allied Health Sciences, University of Sri Jayewardenepura
Published: December 2024

Background: Undernutrition consisting of wasting, stunting, and underweight, among preschoolers is a major public health concern as it results in increased morbidity and mortality. Insights into the proportion and associated factors of undernutrition among preschoolers are imperative for effective interventions. This study was conducted to assess the proportion of undernutrition and its associated factors among preschoolers in Wadduwa MOH area of Kalutara district.
Knowledge, attitudes, and their association with practices on prevention of healthcare associated infections among selected hospital staff categories of teaching hospital Kalutara
Authors:   Faculty of Medicine, University of Moratuwa, Sri Lanka, Chandrarathna H.M.P.S. , Samarasinghe J.A. , Vimalaraj A. , Jayasinghe D.M.De.S.
Published: December 2024

Healthcare associated infections (HAIs) are significant and challenging problems faced by patients as well as healthcare professionals in hospitals worldwide. This study was conducted to determine the association of knowledge and attitudes of selected hospital staff categories of Teaching Hospital Kalutara (THK) with their practices of prevention of HAIs.
Risk factors of knee osteoarthritis among patients attending the orthopaedic clinics at teaching hospital Kalutara
Authors:   Faculty of Medicine, University of Moratuwa, Sri Lanka, Rifdha M.R.F. , Ruberu T.P.W. , Sahra M.N.F. , Sajith A.D.S. , Sasni M.S.M. , Nethikumara U.
Published: December 2024

Knee osteoarthritis (OA) is a leading musculoskeletal condition affecting millions globally, causing significant pain and disability. Identifying risk factors associated with knee OA is essential for its prevention and management. Our study investigated the risk factors of knee OA among patients aged 50 and above attending orthopedic clinics at Teaching Hospital Kalutara.
Digitalizing the pregnancy record
Authors:   Faculty of Medicine, University of Moratuwa, Sri Lanka, Herath H.M.S.N. , Hasanga P.K.D.T. , Haneeka M.H.F. , Hettiarachchi B.R.N.R. , Hewage T.K. , Dayananda N.W.N. ,   Department of Electronic and Telecommunication Engineering, Faculty of Engineering, University of Moratuwa, Warnakula P. ,   Department of Anatomy, Faculty of Medicine, University of Moratuwa
Published: December 2024

Pregnancy requires extensive medical care due to various physical and psychological changes, making thorough antenatal care and record-keeping essential for the health of both mother and fetus. To overcome the inefficiencies, inaccessibility, and lack of real-time monitoring in paper-based systems, digitalizing pregnancy records can greatly enhance the quality and efficiency of antenatal care.
Proportion of caesarean deliveries and maternal and neonatal factors associated with it among mothers delivered in teaching hospital Kalutara
Authors:   Faculty of Medicine, University of Moratuwa, Sri Lanka, Punchihewa R.G.D.G. , Wijenanda I.M. , Panawala C.L. , Cooray W.C.V. , Udage J.B.H. , Goonaratne K. ,   Department of Medicine and Mental Health, Faculty of Medicine, University of Moratuwa
Published: December 2024

Caesarean section is a commonly used surgical procedure performed in obstetrics. Generally, the cesarean section is performed under special maternal and fetal indications. However, it is globally acknowledged that the rates of caesarean section delivery are increasing gradually, due to various maternal and neonatal factors. However, cesarean section entails specific short-term and long-term complications for both mother and baby. This study was conducted to assess the proportion of cesarean delivery and maternal and neonatal factors associated with it among mothers delivered in obstetric wards of Teaching Hospital Kalutara.
Propose a mobile application which can analyze measured health parameters
Authors:   Faculty of Medicine, University of Moratuwa, Sri Lanka, Nawarathna N.M.H.V. , Mathangi R. , Alahapperuma M.C.A. , Mufseer M.M.M. , Perera M.R.K. , Wijesiriwardana C. ,   Department of Information Technology, Faculty of Information Technology, University of Moratuwa, Goonaratne K. ,   Department of Medicine and Mental Health, Faculty of Medicine, University of Moratuwa
Published: December 2024

Modern healthcare systems are faced with great difficulty when managing chronic conditions as they require continuous monitoring and scheduled conducting of treatment for optimized care of the patients. Irregular medical check-ups obstruct the effective management of diseases, early intervention to avoid severe complications and increase the costs of healthcare along with congestion in hospitals. Remote patient monitoring (RPM) can help manage chronic diseases. However, many challenges exist to set back the integration of it into healthcare systems.
Detection of air leakage at the skin – edge of the mask surface with the component of automation in bag valve mask
Authors:   Faculty of Medicine, University of Moratuwa, Sri Lanka, Kiriharan K. , Kanuwana K.P.M.C. , Kariyapperuma P.W. , Kaviraja G.K.M.R.S. , Kumarasiri H.K.S.T. , Gopura R.A.R.C. ,   Department of Mechanical Engineering, Faculty of Engineering, University of Moratuwa, Peries W.A.N.N. ,   Department of Medical Education, Faculty of Medicine, University of Moratuwa
Published: December 2024

The study focuses on improving manual resuscitation bag valve masks (BVM) used in emergencies. Manual BVMs require skilled operation and face challenges like inconsistent ventilation and air leakage. The proposed solution is an automated BVM with air leakage detection at the mask's skin-edge surface. The research aim is the development of a bag valve mask that provides adequate ventilatory support during CPR with minimal air leakage via skin-edge of the mask surface.
Evaluation of machine learning models for bus travel time prediction
Authors:   Department of Civil Engineering, University of Moratuwa, Sri Lanka, Medawatte M.P.V.P. , Perera H.L.K. ,   Department of Civil Engineering, University of Moratuwa, Sri Lanka, Jayasinghe A.B. ,   Department of Town & Country Planning, University of Moratuwa, Sri Lanka, Sumathipala K.A.S.N. ,   Department of Computational Mathematics, University of Moratuwa. Sri Lanka
Published: December 2024

Accurate real-time bus arrival information is essential for an efficient public transport network, as it significantly impacts passenger experience, system reliability, reduced waiting times, dwell times, and operational efficiency. In Sri Lanka's public transport system, current bus arrival time computations primarily rely on static data, neglecting real-time information and critical factors influencing travel times. This highlights the need to identify the unique variables affecting bus arrival times within the Sri Lankan context and to develop robust prediction models that account for these influences. While traditional methods such as Historical Average Models, Regression, Time Series Analysis, and Kalman Filtering have been used in previous research for short-term travel time predictions, Machine Learning (ML) approaches have proven to deliver superior accuracy. ML models are regarded as the most effective for heterogeneous, lane-less traffic conditions with varying traffic volumes, such as those found in Sri Lanka. ML techniques excel in processing large, high-quality datasets and provide accurate predictions by accounting for all relevant variables influencing travel times. Although research has been conducted on developing various basic ML models for travel time prediction, there is a noticeable gap in studies comparing these models to determine the most suitable one for the Sri Lankan context. A Long- Short Term Memory (LSTM) neural network is a deep learning model that is capable of handling long-term dependencies. In the context of bus travel time prediction, LSTMs can leverage historical traffic and travel data to capture temporal patterns and fluctuations that influence travel times. By evaluating LSTMs against basic machine learning models, this study seeks to explore the advantages of applying deep learning techniques to transportation forecasting, ultimately contributing to more accurate and efficient predictive systems in transit planning. The ML models selected in this study include two basic traditional models K- Nearest Neighbours (KNN) and Support Vector Regression (SVR) and four advanced models that utilize ensemble techniques and advanced optimization as Random Forest Regression (RFR), Ada Boost, XG Boost and Gradient Boosting Machine (GBM). The performance of these models was compared with the LSTM model to identify the gap in their accuracies.
Pozycja procesowa pokrzywdzonego w świetle wyników badań instytucji warunkowego umorzenia postępowania karnego
Authors: Juszka Karol
Published: December 2024

Celem artykułu jest przedstawienie pozycji procesowej pokrzywdzonego w postępowaniu w przedmiocie warunkowego umorzenia postępowania karnego. Prezentacja jest oparta na wynikach analizy badań własnych akt sądowych 405 spraw dotyczących efektywności badanej instytucji warunkowego umorzenia postępowania karnego z lat 2003-2009. Rezultatem badań własnych jest przedstawienie postulatów de lege ferenda dotyczących zarówno modyfikacji ustawowej konstrukcji badanej instytucji, jak również działań jakie należy podjąć w praktyce jego stosowania w ramach obowiązujących przepisów.
Metody wykładni prawa stosowane przez Trybunał Sprawiedliwości Unii Europejskiej
Authors: Pikuła Łukasz Jerzy
Published: December 2024

Celem publikacji jest ukazanie metod interpretacji prawa stosowanych przez Trybunał Sprawiedliwości UE. Autor przedstawił interpretację jako zjawisko kulturowe, metody językowe, historyczne, celowościowe, kontekstowe oraz porównawcze, wskazując przy tym na ich znaczenie w kontekście omawianej problematyki.
Dokument w aspekcie historyczno-prawnym
Authors: Lis Artur
Published: December 2024

rzez dokument rozumie się pisemne oświadczenie o treści prawnej, wyrażające jakąś czynność prawną, sporządzoną w wymaganej formie. Dokumenty średniowieczne (dyplomy) spisywano w języku łacińskim na pergaminie (tj. specjalnie wyprawionej skórze). Po uformowaniu się państwa i przyjęciu chrześcijaństwa nastąpiło stopniowe przejmowanie różnych elementów kultury. Jako pierwszy o zapisywanie swych spraw dbać zaczął Kościół. Nastąpiła ewolucja od rozbudowanych i opatrzonych pewnymi for­mułami notycji zapisywanych w księgach ku samodzielnemu dokumentowi spisanemu na osobnej karcie pergaminu. Rozwój dokumentu polskiego odbywał się pod wpływem wzorów czerpanych z zagranicy, głównie z Rzeszy Niemieckiej oraz papiestwa. Następnie pojawił się dokument pieczętny dający uwierzytelnienie czynności prawnych. Właśnie w wieku XII rozpoczyna się ich powolne wprowadzenie do powszechnej praktyki, co zapewne powoduje nie tylko ewolucję ich formy i struktury, ale pociąga za sobą kształtowanie się początków instytucji zwanej kancelarią, a w stuleciu XIII jej szybszy rozwój. Kancelaria kościelna w zakresie funkcji i organizacji nie różniła się zasadniczo od kancelarii świeckich, podlegały one tym samym procesom przemian, wzajemnie na siebie oddziałując, w przeszłości w kancelariach świeckich wiele urzędów powierzano duchownym.
Construction of the Structures of the Polish Workers’ Party in the Districts of the Lublin Voivodeship in the Light of the Documents of the Voivodeship Party Control Commission in the Years 1945–1948
Authors:   The John Paul II Catholic University of Lublin, Bednarczyk Michał
Published: December 2024

The priority of the Polish communists after the end of World War II was the expansion of the small, staff Polish Workers’ Party (PPR) and its transformation into a mass party capable of exercising power. For the leadership of the “workers’ party”, this was a difficult task, since a significant percentage of the society was against their rule, the ranks of the organisation rarely included people worthy of the title of communist, and the field structures were formed in the conditions of the struggle against the Polish independence underground. The article attempts to show the process of building district party organs of power in the Lublin area – an important area with revolutionary and communist traditions dating back to the 19th century for the executors of Joseph Stalin’s will. The source for consideration are archival materials of the PPR Voivodeship Party Control Commission in Lublin.
التنمية الحاكمة للتحول الديمقراطي في السودان: ما بعد الحرب والمسارات المستدامة للأمام
Authors: شيخ الدين قصي , النيل موزان
Published: December 2024

إن التطلع إلى التحول الديمقراطي يكون أقوى عندما يعيش الناس نتائج نقيضه. ومع ذلك، فإن التحول الديمقراطي طر يق صعب يتطلب وسائل يمكن الاعتماد عليها، وإحدى الوسائل البارزة هي إعطاء الأولوية للتنمية المستدامة كجدول أعمال وطني ومن خلال برامج وطنية شعبية. تقدم هذه الورقة حالة للدور الحاسم لحوكمة التنمية في عملية التحول الديمقراطي في سودان ما بعد الحرب. وتقدم استعراضاً تاريخياً للإخفاقات في عدم التوفيق بين الديمقراطية والتنمية في السودان من قبل الأنظمة المتعاقبة، وتدرس دراسات الحالة في قطاعاته الإنتاجية (الزراعة والصناعة والطاقة والتعدين) لإثبات جدوى النهج الرئيسي المتمثل في ’إكساب التنمية طابعاً ديمقراطياً‘، من خلال أمثلة وقصص ديناميكية من الميدان.

سيتطلب التحول الديمقراطي في السودان إعطاء الأولوية لأهداف التنمية المستدامة، ولكي يحدث ذلك، نحتاج إلى دراسة وتخطيط نماذج وأدوات حوكمة التنمية التي يمكن أن تصمد أمام المهمة. توفر هذه الورقة معلومات وأدوات تحليلية للمساعدة في مناقشة الموضوع، من قبل جمهور أوسع ومجموعات من أصحاب المصلحة، بطريقة مستنيرة.
Yerli turistlerin gösterişçi tüketim eğilimlerinin konaklama işletmesi tercihleri üzerindeki etkisi
Authors: Dinç Tansu Elif , Bengül S.süreyya
Published: December 2024

Çalışmanın amacı, gösterişçi tüketimin konaklama işletmesi tercihleri üzerindeki etkisini inceleyen az sayıda çalışma olmasından dolayı ilgili teorik boşluğu doldurmak, bu konuda birçok farklı örneklemde ve ülkede çalışma yapılmışken sabit gelirli bireyler (öğretmenler örnekleminde) üzerinde araştırma yaparak literatürü zenginleştirmek ve konaklama endüstrisinde uygulayıcıların pazarlama faaliyetlerine bir katkı sunmaktır. Bu amaçla, Kütahya il merkezi ve ilçelerinde yer alan Millî Eğitim Bakanlığı’na bağlı devlet okullarında çalışan öğretmenler ve okul yöneticilerinden online anket yöntemi kullanılarak 400 adet veri toplanmıştır. Toplanan veriler üzerinde geçerlilik ve güvenilirlik analizleri, t-testi, tek yönlü varyans analizi, keşfedici faktör analiz, regresyon ve korelasyon analizi gerçekleştirilmiştir. Yapılan analizler sonucunda, gösterişçi tüketimin satın alma tercihleri üzerinde anlamlı ve olumlu bir etkiye sahip olduğu belirlenmiştir. Ayrıca öğretmenlerin gösterişçi tüketim eğilimleri ile konaklama işletmesi tercihleri arasında anlamlı, olumlu ve orta düzeyde bir ilişki olduğu tespit edilmiştir.
Constructing Theoretical Model of Triple Helix Institutionalization Effectivity in Global Value Chains Upgrading
Authors: Hakim Amri , Yandra Alexander , Kabullah M. Ichsan , Kenepri
Published: December 2024

Government collaboration with industry and university in innovation is a necessity to upgrade a country position in global value chains. This article aims to construct theoretical model of triple helix institutionalization effectivity. By using integrating theory method, it is modeled that the process, product, function and intersectoral upgrading determined by agent’s material capability, regime formation which create incentive structure, and trust for each parties. The quality of these independent variables produce the level collaborations as intermediate variable which consist of information and communication stream; coordination in planning and implementation; centrality of effectivity assesment.
Karaeng Electability In Village Head Elections: A Review Of Patron-Client Relations And Capital Power In Bontomate’ne Village, Jeneponto Regency
Authors: A. Rahman A. M. Fatwa , Armin Armin , Ariana Ariana
Published: December 2024

This study explores the role of Karaeng in local politics in Bontomate'ne Village, Jeneponto, to understand the relevance of traditional power in the context of a modern political system. The phenomenon studied involves the transition from traditional governance to modern bureaucracy, as well as the continued political dominance of Karaeng through a patron-client system and resource control. The objectives of this study are to identify how Karaeng maintain their political influence, analyze the inequality of resource control, and evaluate the role of economic, cultural, social, and symbolic capital in their political dominance. Data collection was conducted through in-depth interviews with 22 purposively selected informants. The conclusion of the study shows that Karaeng continue to play an important role in local politics despite the transition to a modern bureaucratic system. The patron-client system in Bontomate'ne Village shows inequality in resource control, with Karaeng having significant control over land and wealth. The mutually beneficial relationship between Karaeng and their followers strengthens Karaeng's political position, while economic, cultural, social, and symbolic capital supports the continuation of their political dominance in Jeneponto society.
Control of the Activity of Mobile Elements in Cancer Cells as a Strategy for Anticancer Therapy
Authors: Pavlov S. R , Gursky V. V , Samsonova M. G , Kanapin A. A , Samsonova A. A
Published: December 2024

An important direction in cancer prevention is the development of novel strategies that can be used in the treatment by affecting the mechanisms of the regulatory pathways and genomic elements involved in malignant transformation. Strategy proposed in this study is to initiate cell death mechanisms in response to the depletion of the energy resources within a cancer cell due to the uncontrolled spread of mobile genetic elements throughout its genome. The calculation results obtained using a preliminary mathematical model that simulates cellular bioenergetic balance, taking into account the energy consumption for retrotransposition of the mobile elements such as LINE-1 and SINE, show that this scenario is plausible. Intracellular resources undergo a critical redistribution when affecting the genomic defense mechanisms and the LINE-1 transcription rate. This leads to a sharp increase in energy consumption for retrotransposon transcription that causes a significant decrease in the pool of free ATPs in the cell.
Cytotoxicity of Gold and Silver Polyacrylates for Tumor Cells
Authors: Ostrovskaya L. A , Korman D. B , Nekrasova E. I , Bluhterova N. V , Hochenkova Yu. A , Abzaeva K. A
Published: December 2024

The study of the cytotoxic activity of two polyacrylic acid-based compounds containing gold (aurumacryl) and silver (argacryl) against a panel of human tumor cell cultures (769-P, Caki-2, SK-RC-1 renal carcinoma lines, BT-474 breast carcinoma, NCI-H211 small cell lung carcinoma) was carried out in vitro. The results obtained were analyzed in comparison with the data established earlier for other cell cultures (MCF-7 breast carcinoma, A-549 lung carcinoma, HCT116 colon carcinoma, Mel Me melanoma). The IС50 cytotoxic index of drugs for the nine tested tumor cell lines ranged from 0.8 to 5.2 µg/ml for aurumacryl and from 0.2 to 14.4 µg/ml for argacryl (in terms of gold and silver content, respectively), varying depending on the type of tumor. Significant differences have been found in the spectra of the lethal effect of aurumacryl and argacryl against tumor cells of various natures.
The Effect of Ethidium Bromide on Purinergic Modulation of Myoneural Transmission and Skeletal Muscle Contraction
Authors: Gorshunova A. N , Teplov A. Yu , Grishin S. N , Mukhamedzyanov R. D , Khairullin A. E
Published: December 2024

The problem of changes in myoneural transmission in the presence of an intercalating agent, ethidium bromide, which has a known inhibitory effect on neuromuscular transmission, has been investigated, but the nature of such an effect remains unclear. To solve the question of the possible participation in this process of known modulators of synaptic transmission – purines (ATP and adenosine), we evaluated their effects in the presence of this agent. After holding the neuromuscular frog preparation in a perfusing solution containing ethidium bromide, the amplitude of postsynaptic responses and muscle contraction forces decreased. Under these conditions, both purines additionally exerted their usual suppressive effect on both the amplitude of postsynaptic responses and the strength of skeletal muscle contraction. Thus, the inhibitory effect of ethidium bromide on neuromuscular transmission is not associated with an increase in the inhibitory effect of endogenous purines caused by the quantum release of the neurotransmitter.
The Action of Dinitrosyl Iron Complexes with a Ligand Based on N-acethyl-L-cysteine upon Inhalation Delivery of These Complexes to Rats
Authors: Timoshin A. A , Shumaev K. B , Lakomkin V. L , Abramov A. A , Ruuge E. K
Published: December 2024

The objective of the present research was to study the action of dinitrosyl iron complexes (DNIC) with a ligand based on N-acetyl-L-cysteine upon long-term inhalation exposure of rats to this substance. It has been shown that as a result, NO stabilized forms pass efficiently through the alveolal membrane into the lung tissue leading to the accumulation of dinitrosyl iron complexes with protein ligands and to an increase in the total NO level in the lungs and other organs thereby inducing a significant and long-lasting hypotensive effect.
Water-Extractable Organic Matter of Soils with Different Degree of Degradation from Erosion and Sedimentation in a Small Catchment in the Central Forest-Steppe Part of the Central Russian Upland (Tillage Soils)
Authors: Kholodov V. A. , Yaroslavtseva N. V. , Ziganshina A. R. , Danchenko N. N. , Farkhodov Yu. R. , Maksimovich S. V. , Zhidkin A. P.
Published: December 2024

Dissolved organic matter is the most mobile part of soil organic matter. At the same time, its change and transformation processes occuring during soil erosion have not been sufficiently studied. The goal of the work was to assess the optical properties of water-extractable organic matter (WEOM) in arable soils of different degree of degradation from erosion and sedimentation in a plowed small arable catchment in the Kursk region. We studied WEOM of arable Protocalcic Chernozems (noneroded and moderately eroded) and their analogue with soil matter sedimentation – Novic Protocalcic Chernozems. WEOM was isolated from aggregates 2–1 and 10 mm. Aqueous extracts were characterized by their organic carbon and nitrogen content. Optical properties were assessed based on absorption spectra and three-dimensional fluorescence spectra. It was shown that in terms of the main quantitative indicators of soil organic matter – the content of organic carbon and nitrogen, as well as the pH value – washed away and reclaimed soils were close to each other and differed significantly from Protocalcic Chernozems. At the same time, both the quantitative and qualitative indicators of WEOM showed a different trend: the WEOM of Novic Protocalcic Chernozems differed significantly from noneroded and moderately eroded Protocalcic Chernozems. Besides, some indicators of WEOM (nitrogen content, SUVA254, S350–400 и SR) depended on the size of the aggregates from which WEOM was obtained (2–1 or 10 mm). In addition, the fluorescent properties of WEOM depend on the size of the aggregates. The obtained data allow us to conclude that the properties of WEOM in a small arable catchment in the central forest-steppe zone are largely determined by the processes of destruction of non-water-stable aggregates and the consolidation of their particles, as well as the leaching of water-soluble organic matter. When aggregates are destroyed by water, their particles migrate with flows along the slope, and organic matter undergoes decomposition; in depressions, particles accumulate, consolidate into blocky structural units, while the properties of their WEOM change significantly, both due to the degradation of organic matter and as a result of its leaching.
Dynamics of the Content of Water-Soluble Forms of Carbon and Nitrogen in Soils in the First Years after Logging
Authors: Startsev V. V. , Severgina D. A. , Dymov A. A.
Published: December 2024

Logging is one of the main anthropogenic factors that change forest ecosystems. An experiment was launched to study the effect of logging equipment on soil properties after cutting spruce forests in the middle taiga of the Komi Republic, during which the laying of drags with different numbers of passes of wheeled vehicles (forwarder PONSSE ELEPHANT) was carried out. Carbon (WSOC) and nitrogen (WSON) of water-soluble compounds play an important role in the global cycle of elements. The article presents the results of observations on the content of WSOC and WSON soils of indigenous forests (Albic Retisols) and deforestation soils that have experienced different loads: portage (3P – three passes of logging equipment, 10P – ten passes, 10P – followed by leveling). A significant increase in total carbon in soils after logging in the first two years was revealed. The greatest changes relate to the upper mineral horizons (EL and TURcwd), in which the carbon content increases 3–6 times (0.32–2.2%) compared with the soil values of the original forest (0.45%). A significant increase in the WSOC content in organogenic (up to 33.4 mg/g) and mineral horizons (up to 0.46 mg/g) soils after continuous logging was found, which is on average three times higher than the baseline values. The content of water-soluble nitrogen increases in the organogenic horizon from 0.23 to 2.12 mg/g two years after logging. In the mineral horizons after logging, the WSON index varied from 0.003 to 0.020 mg/g (values in the soil of the original forest were 0.002–0.011 mg/g). It is shown that an increase in the carbon and nitrogen content of water-soluble compounds can be considered a conditional diagnostic sign of the influence of logging activities on soil organic matter, since concentrations differ significantly from the initial indicators.
Particularities of Hydrolytic Enzymes Pool in Soils of Agricultural Terraces in the Eastern Caucasus
Authors: Chernysheva E. V. , Fornasier F.
Published: December 2024

A study of the influence of farming practices in the Middle Ages (X–XV AD) on the activities of 11 hydrolytic enzymes involved in the biogeochemical cycles of basic elements in soils was carried out. Agrostratozems of medieval agricultural terraces of mid-mountain Dagestan (Plaggic and Hortic Anthrosol) were chosen as objects of study. In all cases, the enzymatic activity of the studied soils, in all soil layers, decreased in the following order: alkaline phosphatase phosphodiesterase acid phosphatase pyrophosphatase ≥ leucine aminopeptidase arylsulfatase chitinase β-glucosidase xylanase α-glucosidase cellobiohydrolase. The enzymatic activity of the studied soils was primarily determined by the amount of microbial biomass (Cmic). Thus, the activity of enzymes of various groups depended on Cmic by 61–94%. Agricultural practices associated with ploughing, manuring, and irrigation lead to convergence in the activity of nitrogen cycle enzymes in soils of the mountain zone, which is associated with similar features of the nitrogen cycle in agrogenic soils, regardless of bioclimatic conditions. The addition of organic materials has led to an increase in the physiological efficiency of microbial communities and the rate of enzyme production, and high levels of biological activity can persist in soil for about 1000 years. Ploughing with the application of organic fertilizers in the past led to an increase in enzymatic activity expressed per unit of microbial biomass (specific activity), and therefore this indicator can be used as an indicator of agrogenic transformation of soils in the past.
A component of the Nigella sativa plant as a radioprotector and antitumor drug
Authors: Fomina D. V. , Abdullaev S. A. , Raeva N. F. , Zasukhina G. D.
Published: December 2024

To date, natural species are widely used as pharmaceutical agents for many human diseases. One of these is the seeds of Nigella sativa and its constituent thymoquinone (TQ). Being a biologically active compound, TQ has a variety of therapeutic properties, including antioxidant, anti-inflammatory, antitumor and a number of others. TQ is an absorber of free and superoxide radicals, therefore it is a promising natural radioprotector against the immunosuppressive and oxidative effects of ionizing radiation. The review presents data on the radioprotective properties of TQ and some mechanisms of its activity. In addition, TQ exhibits antitumor activity by inhibiting cell proliferation, migration and invasion. Despite the fact that TQ induces apoptosis by regulating the expression of pro-apoptotic and anti-apoptotic genes in many types of cancer, the mechanism of action of TQ in oncological diseases has not yet been fully studied. Thus, this review highlights the mechanisms of action of TQ as a promising radioprotector and as a future candidate for antitumor therapy.
Evaluation of the therapeutic effectiveness of a composite agent in the treatment of radiation-thermal damage
Authors: Gaynutdinov Timur R. , Vagin Konstantin N. , Nizamov Ramzi N.
Published: December 2024

The paper presents the results of evaluating the therapeutic effectiveness of a composition based on anti-radiation serum and metabolic products of bifidobacteria on laboratory animals subjected to experimental combined radiation and thermal effects. 124 mongrel white rats of both sexes with a live weight of 180–220 g were used as a biological model in the work. The simulation of radiation damage to the body was carried out by a single external irradiation of animals on a Puma gamma installation with a 137Cs radiation source with an exposure dose of 8.5×10–2 A/kg in an absorbed dose of 7.5 Gy. Thermal injury was inflicted by applying a brass plate heated to 200°C with an area of 4.9 cm2 with a retention exposure of 8 seconds to the trimmed area of the upper third of the thigh, inducing a grade III burn. The effectiveness of the therapeutic drug was evaluated according to the following criteria: changes in the titer of the compliment, the concentration of radiotoxin and thermotoxin, changes in the methodological parameters of peripheral blood, the degree of burn damage, survival and life expectancy of fallen animals. The results of tests evaluating the therapeutic effectiveness of the tested composition showed that a single subcutaneous injection of a medicinal product at a dose of 20 mg/kg followed by application of an anti-burn ointment based on bee podmore and St. John’s wort oil at intervals of 24, 48 and 168 hours accelerated the formation of a burn scab by 1.75 times (p 0.01), complete rejection of the burn scab — by 1.15 times (p 0.05), the complete healing of the burn wound accelerated by 1.18 times compared with the control groups, thereby increasing the survival rate to 87.5% (p 0.05) of animals exposed to two-factor exposure to the affected factors, while increasing the average life expectancy to 28.0 days versus 6.5 days in the control (irradiation + burn).
Evaluating in vitro and in vivo the photoprotective effectiveness of combinations of lichen extracts
Authors: Goncharov Sergey V. , Khramchаnkova Volha M. , Kozlov Alexander E.
Published: December 2024

In a series of experiments, the photoprotective properties of ethanol and ethanol-castor compositions based on perspective combinations of lichen extracts (1:1) were studied in terms of a set of parameters: 1) SPF, λcrit and UV-A/UV-B — in vitro; 2) morphological and functional characteristics of the skin, pro- and antioxidant processes in mice’ blood (line Af) after topical application of the compositions and exposure to UV-A/B — in vivo. In general, photometric studies showed a very high level of photoprotection in all created lichen compositions, which are close to each other quantitatively and approach the category of “sunscreens”. Compositions based on the combination of extracts “ethylacetate Cladonia arbuscula + methanol Ramalina pollinaria” favorably stand out in terms of the combination “SPF — λcrit — UV-A/UV-B”. According to biochemical and morphometric parameters, ethanol and a 30% solution of castor oil in ethanol do not have a noticeable modifying effect on the action of UV on the skin and blood serum and can be used for topical applications of lichen extracts. Among the tested ethanol compositions of extracts in the entire series of experiments at concentrations of 0.2 g/l and 15-20 g/l, according to the sum of the burn severity values at 20 min of UV irradiation, the combinations of extracts “ethylacetate C. arbuscula + methanol R. pollinaria” and “benzene Evernia prunastri + ethanol C. arbuscula” have shown the best photoprotective effect (5-6 points on a 10-point scale). These combinations of extracts worked in a similar way in ethanol-castor compositions, where they showed a less stable photoprotective effect. The introduction of castor oil into ethanol increased the severity of the burn by 6.5-10.5% for all combinations of extracts. The summary of UV effects based on biochemical parameters with a clear direction (GPx, TBARS, TAOC, GSH) shows the photosensitizing nature of all lichen compositions at a concentration of 0.2 g/l. This was observed to the greatest extent for the combination of methanol extracts of Hypogymnia physodes and C. arbuscula. The lowest photosensitivity was noted for the combination of extracts “ethylacetate C. arbuscula + methanol R. pollinaria”, which in various compositions and by the totality of photometric, biochemical and morphometric parameters demonstrated the most expressed photoprotective properties.
EXPLORING THE CAUSES OF ACCOUNTING RESISTANCE IN MSME’s THROUGH MULTI STAKEHOLDER PERSPECTIVE
Authors: Suryantara Adhitya Bayu , Ridhawati Rini , Hanani Tri
Published: December 2024

Micro, small, and medium enterprises (MSMEs) play a pivotal role in Indonesia’s economy, contributing to economic growth and job creation. However, these businesses often face challenges related to financial reporting. Without proper accounting practices, MSMEs lack clarity regarding their profitability and overall business development. Previous research highlights the unpreparedness of MSME actors as a significant barrier to implementing accounting standards (SAK EMKM). This study investigates the relevance of SAK EMKM for MSMEs by exploring stakeholder perspectives. Data were collected through Focus Group Discussions (FGDs) involving participants from various sectors, including PLUT, DJP Nusa Tenggara, conventional and sharia banking institutions, MSME representatives, and educational accountants. The research reveals that the bargaining value between MSMEs and stakeholders is crucial for accounting adoption. When stakeholders exert stronger influence, coercive isomorphism encourages MSMEs to adopt accounting systems. Conversely, if MSMEs perceive their bargaining power as higher, coercive approaches are less effective. Policy makers and decision makers must actively support an enabling environment for MSMEs, emphasizing the importance of accounting information. By doing so, Indonesia can enhance financial transparency, promote sustainable growth, and empower its vital MSME sector.
ПОЛУЧЕНИЕ ОБЪЕМНЫХ КРИСТАЛЛОВ ОКСИХОЛОРИДА СУРЬМЫ И ИССЛЕДОВАНИЕ ЕГО СТРУКТУРНЫХ ХАРАКТЕРИСТИК
Authors: Шонгалова А.К. , Сайлаубек А. , Kемелбекова A.E.
Published: December 2024

Оксихлорид сурьмы (Sb₄O₅Cl₂) является перспективным материалам для применения в фотокатализе, для хранения энергии в калий-ионных аккумуляторах и в качестве огнестойкой добавки для различных материалов. Данная статья подчеркивает важность контроля синтеза для получения кристаллов с улучшенными функциональными характеристиками. В статье представлен процесс получения объемных кристаллов Sb₄O₅Cl₂ методом гидротермального синтеза с использованием хлорида сурьмы, глицерина и гидразин-гидрата. Изучены структурные и морфологические характеристики полученных кристаллов с применением рентгенофазного анализа, спектроскопии комбинационного рассеяния света и сканирующей электронной микроскопии. Полученные результаты показали, что кристаллы кристаллизуются в моноклинной фазе с пространственной группой P2(1)/C, демонстрируя слоистую структуру и плотное расположение зерен. Спектры комбинационного рассеяния света подтвердили наличие валентных колебаний связей Sb–Cl и Sb–O, характерных для структуры Sb₄O₅Cl₂.
Rola fortyfikacji w obronie wschodniej granicy Prus w koncepcjach Karla Wilhelma von Willisena
Authors: Podruczny Grzegorz
Published: December 2024

Karl Wilhelm von Willisen is a lesser-known Prussian military theoretician from the 19th century who, among other things, was concerned with the role of fortifications in war. This article deals with the use of fortifications in the defence of Prussia’s eastern border, the source material for which is provided by three texts written by Willisen between 1832–1868. In these papers, the importance of the fortresses in Toruń, Wrocław, Królewiec, Głogów and Poznań is emphasised. Willisen also considered the construction of the Poznań fortress to be a mistake, as was the failure to rebuild the fortress in Wrocław.
Przemyśl czy Jarosław? Kulisy debaty austro-węgierskich władz wojskowych nad lokalizacją twierdzy nad Sanem
Authors: Baczkowski Michał
Published: December 2024

Discussions regarding the location of the Austro-Hungarian fortress on the San River in Galicia were held between 1868–1871 in the context of preparations for war with Russia. The construction in Jarosław was to support the country’s own offensive operations, while its construction in Przemyśl gave it a defensive character. As a result of France’s defeat in the war with Germany (1870–1871), the idea of locating the fortress in Przemyśl, with exclusively defensive tasks, prevailed.