bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Unilateral Conditioning Activity on Acute Performance Enhancement: A Systematic Review
Authors: Krzysztofik Michał , Wilk Michał , Pisz Anna , Kolinger Dominik , Tsoukos Athanasios , Aschenbrenner Piotr , Stastny Petr , Bogdanis Gregory C.
Published: December 2022

This review aimed to summarize the reported effects of unilateral conditioning activity (CA) on unilateral performance, bilateral performance, and the contribution of activated body limb to bilateral performance. A systematic search on MEDLINE, SPORTDiscus, Scopus, and Google Scholar was conducted on February 2022. Twenty-three studies met the inclusion criteria. Throwing, jumping, swimming, change of direction, and isokinetic performance were used as outcome measures to assess the impact of unilateral CAs on inducing post-activation performance enhancement. Eleven studies examined the effectiveness of resistance exercises as a CA, seven investigated plyometric exercises, and five used isokinetic muscle actions as CAs. Notably, only three studies directly compared the effects of bilateral and unilateral CA, and no study reported possible changes in the contribution of each limb during bilateral exercises executed following unilateral CA. Split squats were the most often studied CA (7), and it was shown that multiple sets of high-loaded split squats (85% one-repetition maximum) executed as CA, improve vertical jumping and change of direction after 4 to 8 min of recovery. At the same time, multiple sets of alternate leg bounds performed with ~10% body weight or without any external load result in an improvement of sprint performance, 2 and 8 min later, with the effect being greater when loaded jumps are used. The unilateral CAs such as split squats, alternate leg bounds, and drop jumps can be effectively used to acutely improve a wide variety of athletic tasks, including jumping, sprinting, change of direction, and swimming performance.
Mateo Tollis de la Roca en la escena teatral madrileña entre 1737-1744
Authors: González Ludeña Carlos
Published: December 2022

Mateo Tollis de la Roca (1714-1781) fue un compositor madrileño de relevancia en el ámbito hispanoamericano, dado que alcanzó el magisterio de capilla de la Catedral de México. Antes de partir al Nuevo Mundo, compuso, en su ciudad natal, una ópera de éxito, La Casandra, estrenada en el Coliseo de la Cruz en 1737, y colaboró estrechamente con la Compañía de José de Parra en la temporada teatral de 1743-1744. Sin embargo, no parece que llegara a ser uno de los principales compositores de los teatros madrileños, por lo que su trayectoria como compositor teatral ha pasado algo inadvertida. Por ello, el presente artículo tratará de arrojar luz acerca de la actividad compositiva de Roca en la escena teatral madrileña.
La Nueva Canción en Lara (1977-2017). Escena musical de la canción protesta en Barquisimeto, Venezuela
Authors: Pérez Valero Luis Ramón
Published: December 2022

Este estudio se enfoca en la presencia de los migrantes chilenos en el estado Lara (Venezuela), y su influencia para transformar una escena local a través del repertorio de la Nueva Canción. El marco conceptual ha partido de las escenas musicales, con una metodología etno y netnográfica, desde la musicología para la producción musical. Se hizo una revisión historiográfica y se levantó información a partir de fuentes documentales y electrónicas. El objetivo principal ha sido describir la interacción entre migrantes chilenos y oriundos en la escena local, y denotar su influencia dentro del circuito local de artistas. Como conclusiones, destaca cómo el repertorio de la Nueva Canción se promovió e hibridó en nuevas propuestas con la música folklórica de la región. Se expone cómo la presencia chilena y el repertorio novocancionista consolidó una transferencia estética con apropiaciones musicales particulares que hacen de esta escena algo único en el contexto venezolano.
Fronteras porosas, sonidos conectados: transnacionalidad de la Nueva Canción a través de sus escritos
Authors: Gavagnin Stefano , Jordán González Laura , Rodríguez Aedo Javier
Published: December 2022

El estudio de la Nueva Canción en América Latina ha puesto en evidencia escenas artísticas cuyos territorios, dinámicas y actores sobrepasan, a menudo, los marcos tradicionales del Estado y sus instituciones. Centrado en el caso chileno, el presente artículo se interroga sobre algunas dimensiones de la transnacionalidad presentes en un corpus bibliográfico específico. En primer lugar, identificamos estudios donde el enfoque transnacional se manifiesta en los marcos generales usados para identificar movimientos musicales. En segundo lugar, examinamos trabajos cuyo objeto de investigación exige una mirada supranacional. En tercer lugar, reflexionamos acerca de trabajos donde el método y el objeto de estudio se cimentan sobre enfoques abiertamente transnacionales. Interrogado desde esta perspectiva, el corpus parece sugerir un mundo musical diverso y heterogéneo, de geografías y dinámicas variables (binacionales, transnacionales, comparativas), donde se articulan y conectan las numerosas capas de la experiencia artística contemporánea.
The economic theory of crime: the history and presence of criminal thought in economic science and its gaps
Authors: Ferreira Gabriela
Published: December 2022

La criminalidad es un tema de investigación históricamente reciente en la economía. Comienza a ganar notoriedad a partir de la Teoría Económica del Delito, desarrollada por Gary Becker a finales de los años 60 y hasta el día de hoy el narcotráfico es una preocupación persistente entre todas las naciones del globo. Dada la importancia del tema, esta nota de investigación pretende desentrañar los orígenes de la Teoría Económica del Delito, así como evaluar su relevancia para el fenómeno actual. Los resultados preliminares muestran que la perspectiva económica ortodoxa es insuficiente para explicar la dinámica del narcotráfico, ya que los actores involucrados en el fenómeno pueden verse influidos por cuestiones políticas y socioeconómicas, no solo por decisiones racionales.
Hegemonía y totalidad ética. La dimensión antimoderna de la hegemonía gramsciana.
Authors: Álvarez Yagüez Jorge
Published: December 2022

Sostenemos la tesis de que el concepto de hegemonía que desarrolló Gramsci es deficiente en dos puntos claves: en dar cuenta de los modos de integración característicos de las sociedades complejas, y en su proyección respecto a la construcción de la sociedad futura. Los dos aspectos están relacionados en cuanto que uno y otro remiten a la concepción de una totalidad ética, vertebrada por una concepción del mundo. El concepto de hegemonía, según esto, debiera superar su honda dimensión eticista. Para la exposición de esta tesis hacemos una confrontación de la posición gramsciana con las observaciones de la gran sociología clásica (Durkheim, Weber) y particularmente con los enfoques de Habermas y Rawls.
El “filósofo democrático” y la posthegemonía
Authors: Moreiras Alberto
Published: December 2022

Este artículo busca problematizar parcialmente la constitución ontológica de la noción de praxis hegemónica en Antonio Gramsci; producir una definición de posthegemonía como posición política y no como doctrina; arriesgar la noción de que, de haber una “ontología” posthegemónica, convendría asentarla bajo tacha en el lugar de un posible pensamiento de la diferencia ontológica; describir brevemente un espacio de praxis emergente en el que la noción posthegemónica se hace explícita; y regresar a Antonio Gramsci a partir de una posible entrada en crisis del concepto de hegemonía en su obra misma.
Gramsci nelle pieghe della postegemonia. Alcune note critiche sulle radici e le contradizioni di una teoria
Authors: Tarascio Giacomo
Published: December 2022

Il seguente contributo presenta una ricognizione sulla teoria della postegemonia e di quella parte al suo interno che può essere raggruppata nella definizione di fondazionale. Questa area di studi si definisce a partire dal rifiuto della relazione tra subalternità ed egemonia, dichiarando la fine della seconda. La particolarità della postegemonia si trova nella radice di questa idea, derivata dall’intreccio tra l’idea di subalternità dei Subaltern Studies e la teoria dell’egemonia sviluppata da Ernesto Laclau e Chantal Mouffe. Dal punto di vista degli studi gramsciani verranno analizzate le due concezioni chiave di subalternità ed egemonia, in particolare come sono state elaborate nelle due correnti menzionate formando le basi della postegemonia. Successivamente sarà analizzata la stessa postegemonia nelle sue due principali ramificazioni, una legata all’infrapolitica e l’altra alla moltitudine.
Poshegemonía, multitud y neoliberalismo
Authors: Castro Orellana Rodrigo
Published: December 2022

El artículo estudia tres formas diferentes de articulación del «discurso poshegemónico»: el uso histórico, la construcción ontológica y las teorías de la multitud, identificado la específica modalidad de negación del concepto de hegemonía que opera en cada una de ellas. Se evalúa el rendimiento de estas críticas desde el punto de vista de su efectividad histórica. Es decir,  considerando su capacidad para diagnosticar adecuadamente las sociedades contemporáneas y su energía para desarrollar un pensamiento y una acción política transformadora que esté en condiciones de suponer un antagonismo sustantivo a las condiciones imperantes del poder en nuestro presente.
SHORT HISTORICAL NOTES XXI
Authors: Gajdoš Anton
Published: December 2022

MEMORY ON OLYMPIC GAMES IN TOKYO 1964
GAMBARAN PREVALENSI STUNTING PADA ANAK BALITA UMUR 24-59 BULAN
Authors: Anasiru M. Anas , Setiawan Denny Indra , Ibrahim Wilka Audina
Published: December 2022

ABSTRACT Stunting or chronic malnutrition refers to  a form of growth failu re.The term is also defined as nutritional status based on body index according to length or height-for-age (L/A or H/A); these terms are the equivalent of the terms stunted and severely stunted.respectively. The purpose of this research was to get an overview of the prevalence of stunting among children aged 24 to 59 months,which conducted in Buhu village, Telaga Jaya sub-district of Gorontalo regency. This descriptive research involved children aged 24 to 59 months. Furthermo re, the sample consisted of 57 children, with one variable, namely stunting prevalence.Indicated that of the 57 respondents had stunting nutritional status; eight children had nulritional status based on body index accord ing to length or height-for-age (L/A or H/A).There were two (3.5%) stunted children, and six (10.52%) severely stunted children. This research concluded that there was 14.02% of stunting prevelence in Buhu village. ABSTRAK Stunting atau malnutrisi kronik merupakan bentuk lain dari kegagalan pertumbuhan. Definisi lain menyebutkan bahwa pendek dan sangat pendek adalah status gizi yang didasarkan pada indeks panjang badan menurut umur (PB/U) atau tinggi badan menurut umur (TB/U) yang merupakan padanan istilah stunted (pendek) dan severely stunted (sangat pendek). Penelitian ini bertujuan untuk mengetahui gambaran prevalensi stunting pada anak balita umur 24-59 Bulan di Desa Buhu Kecamatan Telaga Jaya Kabupaten Gorontalo. Metode penelitian yang digunakan yaitu penelitian desktiptif. Populasi yaitu anak balita yang berusia 24-59 bulan. Sampel penelitian ini berjumlah 57 balita. Variable dalam penelitian ini menggunakan 1 variabel yaitu prevalensi stunting. Hasil Penelitian menunjukan bahwa dari 57 responden yang memiliki status gizi stunting yaitu berjumlah 8 balita dengan status gizi berdasarkan indeks panjang badan menurut umur (PB/U) atau tinggi badan menurut umur (TB/U). Status gizi pendek berjumlah 2 balita (3,5%). Dan status gizi sangat pendek berjumlah 6 balita (10,52%). prevalensi stunting di Desa Buhu yaitu (14,02%) dengan status gizi pendek berjumlah 2 balita (3,5%), dan status gizi sangat pendek berjumlah 6 balita (10,52%).
Comparison of Effect of McKenzie Exercises with or Without Theraband in Patient with Sub Acute Non-Specific Low Back Pain
Authors: Saxena Amar , Khan Abdur Raheem , Naqvi Zia Abbas
Published: December 2022

Non-specific back pain in general refers to any type of back pain that is caused by placing abnormal stress and strain on muscles of the vertebral column. The current study was based on the evaluation of the effect of Mckenzie exercises with theraband for reducing pain, disability and improves the strength in patients with subacute non-specific low backpain. It also evaluated the effect of Mckenzie exercises alone for reducing pain, disability and improves the strength in patients with subacute non-specific low backpain and compared the pain effectiveness of McKenzie exercises with theraband versus Mckenzie exercises alone in reducing pain, disability and improves the strength in patients with subacute non- specific low backpain. he participants for the study were recruited from the population of Integral University at Physiotherapy OPD, Lucknow (UP). On the basis of dependent variables NPRS, ODI, MMT and all the measurements were checked on first day (pretreatment) and last day (post treatment) i.e., after 4 weeks. The subjects were selected according to the inclusion and exclusion criteria and were divided into 2 groups-Group A and Group B. tables showed average difference of ODI, NPRS, MMT showed at 1st to 28th respectively and showed that average difference in pre to post ODI, NPRS, MMT scores was significant in both groups but Group A showed statistically significant difference of pre to post ODI, NPRS, and MMT score in order to decrease pain, disability and in improving muscle strength. Mckenzie exercises with theraband showed statistically more significant difference in ODI, NPRS and MMT score in order to decrease pain, disability and in improving muscle strength.

Key words: Mckenzie Exercise, Theraband, low back pain, ODI, MMT .
A Study to Compare the Effectiveness of Scapular Mobilization v/s Shoulder Mobilization in Patients with Frozen Shoulder
Authors: Upadhyay Vidhi Jha , Sutaria Shivani
Published: December 2022

Background: Frozen shoulder is a painful condition in which movement of the shoulder becomes severely restricted. The condition can vary in severity from mild to severe pain and/or from some to severe restriction in movement.
Aims & Objectives: This study aimed to compare the scapular mobilization along with conventional physiotherapy versus shoulder mobilization along with conventional physiotherapy in patient with frozen.
Methodology: This study designed to double blinded randomized control trial and pre–post assessment study. This study included 30 patients diagnosed with stage 3 frozen shoulders. Divided into two groups, Group A Experimental Study (n=15) received scapular mobilization & conventional treatment and Group B Control group (n=15) received Conventional physiotherapy treatment. Before and after commencing the exercise programmed VAS, Goniometry and SPADI was taken as an outcome measure and the data was analyzed by applying non parametric test.
Result: As the data was not normally distributed non parametric test was used to compare within and between groups.Statistical analysis showed that by applying Wilcoxon test there was significant improvement noted on SPADI (p< 0.03), VAS (p<0.001), and Goniometry (p<0.003) in group A, also the result shows statically significance on VAS (p< 0.05), SAPDI (p< 0.05),and goniometry(p< 0.04), in Group B. while comparing both the groups by Man Whitney U test there was no significant improvement ( P> 0.09).
Conclusion: This study concluded that both scapular mobilization and shoulder mobilization was effective to relieve pain, improve shoulder range of motion and quality of life of patient but scapular mobilization was found to be more effective compared to shoulder mobilization.

Key words: Frozen shoulder, scapular mobilization, shoulder mobilization, SPADI, VAS, goniometry.
Total Knee Arthroplasty in Elderly Patient: A Case Report and Literature Review
Authors: Pratama Ricky Renardi , Oka Dharmayuda Cokorda Gde , Wien Aryana I Gusti Ngurah
Published: December 2022

Introduction: Osteoarthritis is a dynamic and metabolically active disease that involves all tissue components of the joint, bone, cartilage, synovium, muscle, and ligament. Currently, total knee arthroplasty (TKA) is the most common reason for in patient hospitalization; 3 million women and 1.7 million men have undergone knee arthroplasty.
Case Presentation: We report, A male 65-year-old, slightly non-obese Balinese male with an atraumatic progressive painful of his left knee. The patient had become limited to minimal house activity. He required a walker and/or wheelchair for independent mobility at home. According to physical examination and imaging revealed end stage of osteoarthritis, and we performed total knee arthroplasty. The patient had a good postoperative recovery and was discharged to a rehabilitation facility to continue his therapy. He returned to her home after a week post-surgery and walked independently in non-weight-bearing with a walker. Rehabilitation was continued, initially within the home and then outside the home.
Discussion: Treatment designed for knee OA should aim to relieve pain, improve function, and limit disabilities. Knee OA treatment is usually driven by the patient’s symptoms and the potential to improve quality of life.
Conclusion: Total knee arthroplasty is a frequently performed and successful operation. The complications though not common, are challenging to address and require early recognition and intervention with an appropriate referral to a dedicated arthroplasty surgeon with the requisite expertise for revision surgery when necessary to obtain a favorable clinical outcome

Key words: Osteoarthritis, Knee, Total Knee Arthroplasty, Elderly age, Case report..
Parturient with Heart Rate 32bpm for Cesarean Delivery- Anaesthesiologist’s Nightmare
Authors: P. Chaskar Vaishali , Oak Shrikanta , Hemantkumar Indrani
Published: December 2022

Sinus Bradycardia in parturient is very rare condition. It can be associated with hypothyroidism, pathological factors or drug related. Bradycardia may worsen during labour and subarachnoid block due to hypotension. We report a successful anaesthesia management for cesarean section in a parturient with heart rate of 32bpm.

Key words: [Parturient, bradycardia, epidural anaesthesia].
Effect of Sleeve Gastrectomy on the Lipid Profile of Patients with Morbid Obesity Effect of Sleeve Gastrectomy on the Lipid Profile of Patients with Morbid Obesity
Authors: Meena Mukesh Kumar , Singh Aditi , Prisi Shailata
Published: December 2022

Obesity is a kind of malnutrition in which excess body fat has accumulated to the extent that it may have negative effect on health. The treatment of obesity is difficult, weight loss through pharmacotherapy or dietary restrictions have shown to have short term benefits and lack long term benefits. Therefore, surgical treatment is considered as one of most effective procedure for long term perspective. Laparoscopic intervention is preferred method among bariatric surgery. Out of these Laparoscopic sleeve gastrectomy (LSG) is accepted as a primary bariatric surgery for patients with severe obesity BMI > 50kg/m2 due its low risk and easier technique. We planned to evaluate the role of Bariatric Surgery in weight reduction, improved dyslipidaemia with near normo-glycemic status after sleeve Gastrectomy. The study was conducted on 50 morbid obese cases, b/w age 20-40 years with BMI > 35/kg2 who agreed to undergo restrictive bariatric Surgery (sleeve gastrectomy). The study groups were further subdivided into 3 stages-1. Morbid obese subjects selected before Sleeve Gastrectomy as baseline group for serum analysis,2. Morbid obese subjects 9 weeks after Sleeve Gastrectomy,3. Morbid obese subjects 12 weeks after Sleeve Gastrectomy. The results demonstrated significant improvement in levels of parameters like total cholesterol, LDL, triglyceride and HDL at 9 weeks and 12 weeks post surgery in patients with non diabetic status. On contrary in diabetic patients these lipid parameters including serum cholesterol and TG levels didn’t reveal any significant improvement at both 9 as well as 12 weeks post surgery, whereas LDL showed significant improvement at 9 weeks but not at 12 weeks. HDL levels were significantly increased at both 9 weeks and 12 weeks post surgery in diabetic patients. Improved glucose metabolism after Sleeve Gastrectomy may be mediated by an improvement in the insulin Resistance. Moreover, improved lipid metabolism after Sleeve Gastrectomy leads to increase in HDL-C and decrease in LDL-C, which can possibly reduce the risk of cardiovascular disease. Properly controlled studies with larger cohorts are necessary to elucidate the beneficial effects of bariatric surgery.

Key words: Bariatric surgery, Blood glucose, Diabetes, HDL-C, Laparoscopic Sleeve gastrectomy, LDL-C, Lipid profile, Morbid obesity, Triglycerides, Total cholesterol .
Antifungal Activity of Aloe Vera Extracts Against Phytopathogenic Fungus Aspergillus Spp.
Authors: Bhatnagar Nupur , Sharma Mudit , Naz Faridi Farah
Published: December 2022

Medicinal plant contains many natural products to perform antifungal activity. The present study was undertaken to determine the antifungal activity of Aloe vera gel with ethyl acetate and methanol extracts against the Aspergillus spp. The fungus was isolated using standard potato dextrose agar. After identifying the fungus based on their morphology they were subjected to various biochemical tests. Gas chromatography-mass spectrometry (GC-MS) analysis was also performed to determine the content of Aloe vera gel with ethyl acetate and methanol extractions. The Aloe vera gel with methanol extract was found to have high yield as compared to ethyl acetate extract. The methanol extraction of Aloe vera also showed high inhibition rate of fungal flora as depicted by colony forming unit (CFU) method. Further studies are recommended to ascertain the role of Aloe vera with other solvent extracts as a potent pharmacological and therapeutic agent

Key words: Antifungal activity, Aloe vera, extracts, GCMS
Some Serum Cytokines (Adiponectin, Apolipoprotein B, hsCRP, IL-6) in a Cohort of Type 2 Diabetes Mellitus Patients
Authors: Chidinma Agu Nneka , Ogbonna Ogbuabor Alphonsus , Nwachukwu Okwuosa Chigozie
Published: December 2022

Diabetes mellitus has over the years become a public health challenge and a complex disease which is characterized by chronic hyperglycemia that results in microvascular and macrovascular complications. The present study was designed to determine the serum IL-6, hsCRP, Adiponectin and apolipoprotein B levels in patients with type 2 diabetes mellitus (T2DM) and controls. A total of 180 subjects comprising 90 type 2 diabetic patients and 90 healthy controls were recruited for the study. Blood samples (7.0ml) were collected from each subject for the analysis of the cytokines, using Enzyme Linked Immunosorbent Assay kit obtained from Sunlong Diagnostic Ltd,China. Data was analysed using T-test, one way analysis of variance and the Turkey post hoc test with level of significance set at p < 0.05.The results revealed increase in hs CRP (10.22 + 0.80ng/ml), , Apoliprotein B (300.07 + 23.96ng/ml), IL-6 (21.49 + 2.86ng/ml) in the T2DM patients compared to the hs CRP (2.80 + 1.66ng/ml). Apoliprotein B (261.45 + 5.69ng/ml) and IL-6 (4.83 + 1.25ng/ml) for the controls. There was a decrease in the level of Adiponectin (6.70 + 0.64ng/ml) in the T2DM patients compared to (11.04 +0.81ng/ml) for the controls. This finding supports the claim for cytokine deregulation in T2DM patients.

Key words: Cytokines, Adiponectin, Apolipoprotein B, hs CRP, IL-6, Type2 Diabetic Mellitus
Coumarin Hydrazide: Chemistry, Synthesis and Pharmacological Activities - A Review
Authors: Shaji Neethu , M J Nair Sandhya , S Dharan Shaiju
Published: December 2022

Coumarins are heterocyclic compound with a benzopyrone structure. Coumarins are a large group of organic compounds found in several plants even in bacteria and fungi. The biological activities of coumarins and its derivatives includes anticoagulant, anticancer, antiulcer, antifungal, anti-HIV, antimicrobial, antiosteoporosis, antioxidant and anti- inflammatory activity. Hydrazide-hydrazone derivatives act as structural sub units in many pharmacologically active compounds including coumarins to give biological activities like antimicrobial, anticancer, antifungal, anti-inflammatory, antiviral, anti-tubercular, and antiprotozoal activity. The interest in the synthesis of coumarin derivatives has been gaining importance over the last decades, reflecting the importance of such compounds in both medical and chemical research. In this review hydrazide-hydrazone derivatives of coumarins are taken into consideration and emphasised on the anticancer, antitubercular, antimicrobial, antioxidant and antidiabetic activity of these derivatives.

Keywords: Coumarin, hydrazide, heterocyclic, benzopyran, antitumor, antimicrobial, antioxidant
A Study to Assess the Prevalence of Medication Related Problems in Elderly Patients
Authors: Pradhan Abhishek , Sudha Sanjay Jayakumar , Shabaraya A.R
Published: December 2022

Medication-related problems are referred to drug therapy that interferes with or can intervene with the preferred health outcomes for a patient. The geriatric populace that almost represents 21% of the whole populace, devours a remarkable deal of drug treatments due to the age-associated physiological changes, pharmacokinetic and pharmacodynamics alterations, consequently developing into medication related problems. The high prevalence of multiple drug use with age-related changes in pharmacokinetics and pharmacodynamics makes elderly patients vulnerable to medication-related problems.
A community-based observational study was conducted among the residents who met the inclusion and exclusion criteria belonging to different regions of Dakshina Kannada district. The duration of the study was 6 months and enrolled 150 elderly patients aged 60 years and above of either sex and diagnosed to have any disease except cancer and being bedridden , to assess the prevalence of medication-related problems in elderly patients.
Out of 150 elderly patients enrolled in the study, 107 were identified to have Medication Related Problems (MRPs). A total of 196 MRPs were identified amongst those 107 patients. The prevalence of patients with MRPs was found to be 72% in this study. The prevalence of MRPs was found to be varying among males (68.29%) and females (75%), across different age groups & others.
So, the study concluded that the number of elderly patients and multiple co-morbidities are increasing consequently with the increase in the number of medications and thus leading to increase in MRPs. So, it's vital to ensure optimum care for positive outcomes in the elderly.

Keywords: Medication-related problems, MRPs, elderly patients, geriatric populace
Individual approach in treating patients with pulmonary and tracheobronchial tuberculosis, with a long history of tobacco smoking and decompensated diabetes mellitus
Authors: Chumovatov N. V. , Chernyh N. A. , Saharova G. M. , Antonov N. S. , Romanov V. V. , Ergeshov A. E.
Published: December 2022

Introduction. At the end of 2020, the clinical cure rate in all registration groups of patients with pulmonary tuberculosis was 48.2 %. There is now ample evidence that additional risk factors influence the more severe course of pulmonary tuberculosis and reduce the effectiveness of standard anti-tuberculosis therapeutic programs. Diabetes mellitus and tobacco use are among the significant risk factors. Complementing standard TB therapeutic programs with nicotine addiction and diabetes mellitus treatment programs with the formation of an individual comprehensive patient treatment plan will increase the effectiveness of TB treatment. Thus, the goal of this work is to demonstrate the high effectiveness of an individualized approach to the treatment of a patient with pulmonary tuberculosis with a comorbid background.

The aim of the work was to demonstrate the high effectiveness of an individualized approach to the treatment of a patient with pulmonary tuberculosis with a comorbid background.

Materials and methods At the Central TB Research Institute the patient underwent a comprehensive examination, including mandatory, additional and facultative methods of investigation. Based on the findings, the patient underwent complex treatment: antituberculosis chemotherapy, correction of carbohydrate metabolism disorders using oral antidiabetic drugs, nicotine replacement therapy according to the selected scheme, taking into account the degree of nicotine addiction.

Results and Discussion Against the background of complex treatment, by four months of therapy the following was achieved: knockdown of systemic inflammatory reactions, cessation of bacterial excretion, compensation of diabetes mellitus. X-ray examination revealed closure of a large decay cavity, resorption and consolidation of focal infiltrative changes. There was regression of infiltrative changes of trachea and bronchi. The patient completely stopped using tobacco due to nicotine replacement therapy.

Conclusion This clinical example demonstrates the high effectiveness of an individualized approach to the treatment of tuberculosis, including the need for an individualized regimen of anti-tuberculosis therapy, adequate compensation for diabetes mellitus, and the implementation of relevant smoking cessation techniques among smokers with pulmonary tuberculosis.
Principles of bioethics in the work of a nurse during the mass vaccination of adults against COVID-19
Authors: Lapickaya T. Yu.
Published: December 2022

Introduction. The bioethical principles in the work of a nurse during the vaccination of the population against COVID-19 were discussed in the article. Emphasis on the role of the nurse in communicating with patients is placed in the article.

The purpose of this paper is to identify the key principles of bioethics that are most significant in the nursing profession.

Materials and methods The analysis of 15 documentary and literary sources found in the databases and electronic libraries Cyberleninka, ConsultantPlus, garant.ru. The study was carried out by means of the method of content analysis of legal acts.

Results and Discussion The content analysis of the normative-legal acts regulating the citizens' right to health protection and the sphere of vaccine prophylaxis of the population, scientific literature allowed to estimate the order of COVID-19 vaccination organization and the nurse's role in this process. The problems of complexity of vaccination decision-making on the part of the adult population were revealed. Showed the moral and ethical qualities that the nurse must possess.

Conclusion As transhumanism develops, its irreversible consequence is the erasure of the principles of humanism in medicine
Threat-measuring capabilities of the NTISS scale in the pre-transport phase of neonatal preparation
Authors: Kovtun O. P. , Davydova N. S. , Mukhametshin R. F. , Kurganski A. A.
Published: December 2022

Introduction. Medical evacuation of newborns in critical condition remains an important area of neonatal intensive care. The study of threat-metric tools for assessing severity during the inter-hospital transport phases is of considerable practical interest.

The aim of the study was to determine the ability of the NTISS scale to predict neonatal outcomes during the pre-transplant preparation phase, depending on the score obtained.

Materials and Methods The cohort study includes data from 604 visits of the resuscitation and consultative center (RSCC) transport team to newborns under remote monitoring by the RSCC between August 1, 2017, and December 31, 2018. Division of the total sample into subgroups according to the score on the studied scale, with subsequent comparison of characteristics and outcomes in these subgroups was performed.

Results In the subgroup of patients with a score of 30 or more there was a significant predominance of children with a birth weight of less than 1000 grams (85.72 %); in the subgroup with a score of 0–9, children with a birth weight of more than 2500 grams accounted for 83.33 %. Similar patterns were observed in the analysis of gestational age. Analysis of the volume of intensive care indicates an increase in the proportion of patients requiring high-frequency ventilatory ventilation, dopamine and adrenaline infusion as the NTISS score increased. When analyzing outcomes in the overall sample, there was an increase in the proportion of fatal outcomes from 0.00 % to 75.00 % as the NTISS score increased.

Discussion The NTISS scale, being a therapeutic profile instrument, divided the sample according to the need for intensive care, which was significantly associated with birth weight and gestational age. Thus, the observed differences in outcomes are a legitimate result of the prevalence of extremely premature infants at high NTISS scores.

Conclusion The NTISS scale demonstrates a reliable division of patients by severity and predicts the outcomes of the hospital phase of treatment.
Problems of implementing the federal project "Development of export of medical services" at the regional level
Authors: Moskvicheva M. G. , Safina E. R.
Published: December 2022

Introduction. The purpose of the study is to determine the leading and least represented on the website of the Federal project "Development of exports of medical services" (Federal project) profiles of medical services for the formation of proposals for the development of medical tourism in the Chelyabinsk region.

Materials and methods The study is based on empirical and theoretical methods of studying the website of the Federal Project and the information of the Coordinating Center for Medical Tourism Development placed on the websites of the Ministry of Health of Russia and Central Research Institute of Health Organization and Informatization. Statistical method and questionnaire survey method were used.

Results and Discussion Factors influencing the choice of medical organization are: availability of information about the medical organization in free access, transport accessibility, staffing of hospitals with equipment, level of professional training of doctors, quality of service and patient safety in medical organizations, the cost of medical services. Leading areas of medical tourism for adult patients: obstetrics and gynecology, neurology and neurosurgery, traumatology and orthopedics. Rating of medical services profiles for children's age category of foreign tourists: pediatrics, rehabilitation, ophthalmology, neurology, otorhinolaryngology and dentistry. The main factors motivating managers of medical organizations to participate in the Federal project: attracting additional funds, development of quality system management and obtaining a JSI certificate, improving the image of the medical organization in the framework of medical tourism. Reasons that hinder participation in the project: lack of targeted funding, problems of interaction with the project organizers, maintenance and processing of permits for medical tourism, pandemic conditions.

Conclusion The condition for effective implementation of the Federal project in the Chelyabinsk region is to create a Regional Coordinating Center, which will organize and carry out activities aimed at the development of medical tourism in the region and the promotion of medical organizations in the Chelyabinsk region.
Characterization of treated and untreated Sawdust and its Valorization as Adsorbent
Authors: A Boukraa. , M. M Messaoui.
Published: December 2022

Lignocellulosic residues can be used in wastewater treatment as clean, natural and low cost adsorbents. In the present study, our approach is to develop the preparation and characterization by physicochemical methods of an adsorbent material, from mixed red and hard wood sawdust. The preparation of the adsorbent material includes the sieving of the sawdust, the extraction of the extractables, a pretreatment with sulphuric acid H2SO4 (at 20% to 50% and at 80%) as an activating agent. The chemical modification, which serves to improve the adsorption capacity of the material, is verified by means of analysis: Fourier Transfer Infrared (FTIR) and X-Ray Diffraction (XRD) (crystallinity index). The chemical modification of the lignocellulosic material induced a significant elimination of hemicelluloses, which resulted in the appearance of a new microstructure, especially in the case of acid pre-hydrolysis at 50% and 80%, in favor of increasing its potential adsorption capacity proven by testing it on the adsorption of acetic acid.
A Simple Group-Interaction Contribution Method for the Prediction of the Freezing Point of Ionic Liquids
Authors: Mokadem Khadra , Mohemed Lakhdar Belfar , Tumba Kaniki , Saad Abed Abdulqader , Korichi Mourad
Published: December 2022

A linear model based on group-interaction contributions is proposed for the estimation of the freezing temperature (Tf) of ionic liquids (ILs). This property is important for modelling solid-liquid equilibrium and selecting ionic liquids as reaction media among other things. A database of 66 experimental freezing points different ionic liquids was used to obtain all interaction contribution parameters and model constants. The database included various classes of ionic liquids and a wide range of cation and anion groups., with an average absolute relative deviation of 4,09% and a correlation coefficient of 0,93.
Predictive QSAR models for the toxicity of Phenols
Authors: Hamada Hakim Auteur
Published: December 2022

Toxicity data for the 50% growth inhibitory concentration against Tetrahymena pyriformis pCIC50 = -logCIC50 for 85 phenols substituted were obtained experimentally. Log (CIC50)-1 along with the hydrophobicity, the logarithm of the 1-octanol/water partition coefficient (log Kow), and R2u (GETAWAY descriptors). The entire data set was randomly split into a training set (60chemicals) used to establish the QSAR model, and a test set (25 chemicals) for statistical external validation The descriptors models were selected from an extensive set of several descriptors (topological, geometrical and quantum). Quantitative structure-activity/property (QSAR / The values of the statistical parameters obtained from the multiple linear regression analysis (R²=95.5%, Q²=95.01%, S=0.157, F=604.34, P=0, SDEC=0.153, SDEP=0.161, Q²ext=95.96%, SDEPext=0.153) testify to the good fit of the model.
A Validated Potentiometric Titration Method for Quantitative Determination of Molnupiravir from Pharmaceutical Preparation
Authors: Rajan V. Rele , Prathamesh P. Tiwatane
Published: December 2022

A simple precise, rapid accurate and sensitive non-aqueous potentiometric titration method was developed for quantitative determination of molnupiravir from pharmaceutical dosage form. The titration was carried out using standardized 0.1 N perchloric acid. The proposed method was found to be precise with % RSD <1 (n = 6). The method showed strict linearity (r2 > 0.9999) between 10 % to 50 % w/v of 100 mg of drug substance weight. The percentage recovery of molnupiravir in the optimized method was between 99.05 to 99.81 %. The method is also found to be rugged when checked by different analysts and using different lots of reagents and different makes of titrators.
Modeling of Log Kow of a Series of PAHs using Computational Chemistry
Authors: Mebarki Fatiha , Meneceur Souhaila , Bouafia Abderrhmane
Published: December 2022

The importance of Chemometrics Methods in Modeling (in QSAR analysis) of the mathematical model’s study of large datasets of molecules with huge numbers of physicochemical and structural parameters quantitative structure-Toxicity relationship (QSTR) are mainly based on multiple regression analysis in QSAR analysis The study of Least Square in deriving QSTR models for datasets of Quantitative Structure-Toxicity relationship on Log kow (Octanol-water partition coefficient) for 16 Hydrocarbons compounds has been using the software Hyperchem 6.3 for computing descriptors and MINITAB 16 for data modeling. A three -descriptors model [two electronics molecules’ descriptors (QSER descriptor), HOMO (is Highest occupied molecular orbital) and LUMO (Lowest unoccupied molecular orbital), one QSAR descriptor E_H (Hydration Energy) by Least Squares with correlation coefficient r=0.868, S=0.635, R2 = 75.4%, R2ajd=73.7% and Durbin-Watson statistic =1.85277 and graphical analysis by diagram of goodness of fit and line plot. The results statistical of new model after removing the aberrant compounds (Toxicity compounds) shows high Coefficient of correlation r=0.9581, S=0.4316, determination coefficient R2 =91. 8%, ajustemed R2ajd = 89.3%, Durbin-Watson statistic D=2.373, Three explanatory Variable model selected is robust and has good fitness. Two influential compounds detected and important the model and absence aberant compounds of the studied sample.
Ethnomedicinal, Phytochemical and Pharmacological properties of Pistacia atlantica Desf. (Anacardiaceae): Review
Authors: Bakka Chahrazad , Smara Ouanissa , Dendougui Hocine , Hadjadj Mohamed
Published: December 2022

Pistacia atlantica belongs to the Anacardiaceae family, it has been widely used in the Middle Eastern and Mediterranean areas since ancient times. Pistacia atlantica has been used for different diseases like stomach, pain, peptic ulcer, wounds, renal disorders, and coughs. This study aims to review its ethnobotanical characterization, traditional uses, phytochemistry, and pharmacological activities found in this plant. The data in this review article was based on electronic databases such as Web of Science, Springer, Yahoo search, Science Direct, PubMed, and Google Scholar for papers published from 2016 until March 2021 are considered. The results showed that Pistacia atlantica has many medicinal properties such as antioxidant, antidiabetic, anticancer, anti-inflammatory, and others. Phytochemical has shown the presence of numerous valuable compounds, including volatile compounds, fatty acids, phenolic compounds, and flavonoids. In this regard, the ethnomedicinal, phytochemistry, biological, and pharmacological properties of Pistacia atlantica have been reviewed here.
Review on Forced Flow Thin Layer Chromatography: An updated Analytical Technique
Authors: Karati Dipanjan , Ghosh Somsubhra , Pati Parna , Ganguli Debgopal , Saha Puja
Published: December 2022

Chromatography is a method for the isolation of a mixture into separate sections. It is usually based on the principle of partition of solute between two phases. It usually consists of a mobile phase and a stationary phase. The advancement of the mobile process in the planar stationary stage is evoked by different external or internal forces. Capillarity and gravity are the intrinsic force whereas external forces are electric field, pump, and centrifugal forces. Thin layer chromatography and high-pressure thin layer chromatography are based on the adsorption theory. Forced flow thin layer chromatography is also based on the adsorption principle. FFTLC is an authoritative method of separation that uses a solvent pump to extract the sample mixture into a pressurized ultra-micro cavity containing an adsorbent analytical or preparative planer bed. FFTLC needs no or slight sample preparation as in TLC. One relation between FFTLC and high-pressure liquid chromatography is that as in HPLC, the maximum layer length is used for analytical and preparatory separation. FFTLC is a process in which continuous production and continual evaporation of the mobile phase from the end of the chromatography plate produces forced-flow. Here, we focus on FFTLC, an advanced and more sophisticated chromatographic technique.
Factors Influence the Performance of Training Organizations: A Study on Bangladesh Public Administration Training Centre
Authors: Islam Md. Zohurul , Asrafujjaman Syed , Hosen Shamim
Published: December 2022

Bangladesh Public Administration Training Centre (BPATC), an apex training organization, is a key player in the development of public sector human resources by offering and arranging high-quality training programs. A current curriculum and qualified training professors and staff are required for quality and effective training. As a result, the study's goals are to identify variables that determine training institution performance and as well measuring factors that influence, or impact training organizations’ performance and policy implications are drawn. A quantitative approach is adopted and as a research technique employs a highly known and frequently utilized structured questionnaire survey instrument. The respondents' data is collected using a purposive sampling approach. For data analysis, a scholarly software program called SPSS is employed. In addition to descriptive statistics, principal component factor analysis is used in this study. Unstandardized Coefficients values with significant levels (p<.001) are used to test stated hypotheses and ANOVA is used to evaluate model significance. For organizational performance, PCA has identified four variables. Factors have high loading values. Among the four hypotheses, regression results confirmed that only one hypothesis ‘training staff relationship’ is having a positive and significant relationship with training organizations’ performance.
Financial Performance Analysis of Banks – A Study of SBI
Authors: Kumar Gulshan , Kapoor Gaurav
Published: December 2022

Banking Industry in India is led by Public Sector Banks (PSB) with a big share in the Indian market. The present study is to compare the financial performance of SBI with the industry averages on the basis of financial ratios for the period 2016-17 to 2020-21. It was found that the solvency position of SBI and the employment of assets are far better than the industry and the other banks. The employment of shareholders’s funds and CASA of SBI is also better than the industry and other banks.
An Empirical Study on Issues and Challenges of Corporate Social Responsibility Activities in India
Authors: Debnath Prashant , Chellasamy P.
Published: December 2022

Corporate social responsibility (CSR) is a management idea where companies incorporate their socio-environmental problems into their operations and maintain good relations with its stakeholders. Recently government of India has implemented new CSR regulation. The Companies Act of 1956 was repealed and the Companies Act of 2013 was enacted in its place. Section 135 of the companies Act of 2013, a new section of the new act, set certain provisions on corporate social responsibility for entities doing business in India, which resulted in a significant change in the creation, administration, and governance of companies. India has been the first country among all other nations to mandate the requirement to engage in CSR activities and to disclose it under the Companies Act of 2013. This signals the commencement of a new era in India's corporate social responsibility. All organizations that qualify for CSR requirements will be required to spend 2% of revenues on CSR within a specified time frame or turn this money over to government-run entities. In the present time of Covid-19 outbreak, the Indian government motivating Indian entities to give some assistance to the community. According to a circular of March 23, 2020 Ministry of Corporate Affairs, All Covid-19 related expenditure would be considered as CSR expenditure. In this study, researcher has made an effort to study the present scenario of CSR, including CSR practices followed by companies during a pandemic and the issues and challenges related to CSR, including making suggestions as to how these challenges can be resolved.