bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigating the Impact of Experiential Learning on Vocabulary Memorization and Language Production: A Quantitative Study among Moroccan Young English as Foreign Language Learners
Authors: Chankob Atimade , Hdouch Youcef
Published: February 2024

This study explores the effects of experiential learning (EL) on vocabulary memorization and language production in English as a Foreign Language (EFL) among 4th-grade primary school students in Morocco. Two 4th grade classes were involved, with one class receiving traditional instruction over five weeks and the other class immersed in experiential learning through concrete situations. The current investigation endeavors to overcome the shortcomings associated with traditional approaches by examining the potential benefits offered by experiential learning methodologies. Preliminary results indicate a noticeable difference in vocabulary memorization and language production between the two groups. For instance, the experiential learning group demonstrated a deeper understanding of the vocabulary related to the supermarket theme by actively engaging in role-playing scenarios where they simulated grocery shopping. The traditional instruction group, while also exhibiting improvement, did not showcase the same level of enthusiasm and retention. The findings suggest that experiential learning positively influences vocabulary memorization and language production among 4th-grade primary school students. In other words, by incorporating real-life situations into the learning process, students not only acquire language skills but also gain a practical understanding of the context in which these skills are applied. In sum, through the lens of the quasi-experimental design, this study addresses the inadequacies of these traditional methods by exploring the potential benefits of experiential learning approaches, aiming to provide a more holistic and applicable foundation for language acquisition among ELF young learners.
Social Culture Formation and Development of Village-Owned Enterprises as a Hybrid Organization in Indonesia: A Case Study in East Java
Authors: Asmuni  , Raden Andi Sularso  , Supranoto  , Patriadi Himawan Bayu
Published: February 2024

This study aimed to describe the development of Village-Owned Enterprises (BUM Desa) in Indonesia as hybrid organizations. A hybrid organization is formed with different institutions and becomes a new institution. In general, the new institution was created with a double mission. One remains for business-oriented, the other for social purposes. The study followed the guidelines for Village-Owned Enterprises designed uniformly to be implemented by all villages. This study uses studies in East Java to photograph Village-Owned Enterprises in Indonesia. Based on this case study in East Java, Village-Owned Enterprises was found to grow differently following the lines of the socio-cultural area. The results of this study found two important things. First, several Village-Owned Enterprises were successfully formed and then developed into Village-Owned Enterprises with the Advanced category; some villages failed to form Village-Owned Enterprises; some of them succeeded in establishing Village-Owned Enterprises, but the development was not good enough, so they were still the Beginner category. Second, even though it is based on formal institutions that are uniform and apply nationally, the process of forming and developing Village-owned Enterprises in East Java Province, according to initial expectations, turns out to follow the sociocultural divide. Regions with Mataraman and Arek socio-culture generally produce more Village-Owned Enterprises in the Advanced category. Meanwhile, the area with the Pandalungan socio-culture is relatively stagnant because it only produces a few Village-Owned Enterprises in the Advanced category. In conclusion, Village-Owned Enterprises grow differently in different socio-cultural areas. Socio-culture is a supporting factor in the formation and development of Village-Owned Enterprises.
Drug Consumption: Analyzing A Series of Urine Samples from Algiers Addicts by GC-MS Low Cost Derivatization Method
Authors: DALI BRAHAM Lokmane , KADDOUR Salma , BRAHIMI Asma , AMOKRANE Souhila
Published: February 2024

The complex and evolving landscape of drug addiction poses significant public health challenges in Algiers, Algeria. With growing concerns about drug addiction and its associated consequences, it becomes imperative to comprehensively understand drug consumption patterns among individuals grappling with addiction in this region. Drug addiction is a multifaceted issue influenced by various factors such as drug availability, sociodemographic characteristics, and personal choices. The prevalence of drug addiction continues to rise, warranting a thorough examination of the specific substances that dominate the local addiction landscape. A descriptive retrospective analytical study was conducted, analyzing 92 cases of drug consumption profiles among addicts in the Algerian province of Algiers. Urine samples collected between January 1, 2020, and October 15, 2022, from drug-addicted patients in Algiers, were examined using Gas Chromatography-Mass Spectrometry (GC-MS). The meticulous analysis of this diverse population revealed that THC and pregabalin are the two most frequently consumed substances, often used together in poly-drug combinations. Surprisingly, there is a notable prevalence of opioid consumption, especially within families, raising concerns about a potential opioid crisis in Algiers.
EFFECTS OF Azadirachta indica, Parkia biglobosa AND SYNTHETIC INSECTICIDES ON Sesamia calamistis (HAMPSON) ON GROWTH AND YIELD OF MAIZE (Zea Mays L.) IN MAKURDI
Authors: Gambari L. I. , Babatunde Samuel F. , John Ojonimi A. , Akor Raymond U. , Ogbaje S. Ojomola , Ajuu Stephanie N. , Tyoapine Terver S.
Published: February 2024

Zea mays, plays a crucial role in the dietary habits of numerous individuals residing in Nigeria. Several factors, including the presence of Sesamia calmistis and the effects of synthetic insecticides on beneficial insects and hazards to humans, contribute to the limitation of maize output. The study evaluated the effect of Azadirachta indica and Parkia biglobosa extracts on the control of S. calamistis and this experiment was carried out in two planting seasons of 2021 and 2022. The experiment was carried out at the Teaching and Research Farm, Joseph Sarwuan Tarka University, Makurdi. Three treatments; A. indica, P. biglobosa, Karate 5 EC (Lambda cyhalothrin 5 EC) and control were used. From the study, A. indica extract had a significant effect at p<0.05 on the insect population resulting in a significant increase in the yield parameters which includes the number 100 seed weight of the plant, yield in both 2021 and 2022 planting season with the mean value of 5298.21 and 5428.98 kg/ha respectively. The use of A. indica extract was observed to be effective in the control of insect population and leading to maximum productivity of maize low infestation by observing the maize plant with borers tunnels to be lower in A. indica extracts and Karate 5 EC plots with the mean value of 3.00 and 3.00 in 2021 planting season respectively at p<0.05. The percentage of dead hearts at 60 days after treatment in 2021 and 2022 cropping seasons was significant at p<0.05%, with the control plot having the highest...
DETERMINANTS IN NATIONAL HEALTH INSURANCE SCHEME AWARENESS AND PARTICIPATION IN KADUNA STATE
Authors: Ekpo Regina , Mamman M. , Akpu B. I. , Arigbede Y.
Published: February 2024

National Health Insurance Scheme (NHIS) is a social basic service offered by the Federal Government of Nigeria to its citizen, in order to achieve universal healthcare (UHC) coverage but its progress seems to be facilitated or hindered by some factors. This paper seeks to access the determinants of NHIS participation of Kaduna State. Adopt multiple stages sampling in the collection of data from 400 respondents. Frequencies, percentages and tables were used to present results obtained but applied Pearson product moment correlation coefficient to test for significant relationship at 0.01significant levels. The result shows that majority (80.1%) of NHIS participants in the study are within the productive and reproductive age group, married with children, have a minimum household size of five but enrolled 3-4 family members (28.8%), educated, 45% are income earners that obtain health services from mainly private HCFs with distance that is less than 5km, and awareness in NHIS had positive relationship with age, sex, number of children and household size. Positive relationship existed between age, household size, education, monthly income earned and immediate participation in NHIS while duration in NHIS participation had positive relationship with income and immediate participation in NHIS but employment status had a negative relationship. The paper recommends a comprehensive public awareness on NHIS participation that surpasses the office environment and encourages informal sectors to participate in NHIS is needful and avoids delay in participation after been informed about the scheme, for a successful UHC coverage.
Kearifan Lokal dalam Pelayanan Kesejahteraan Sosial Saat Kebencanaan (Refleksi Pengalaman Masyarakat Saat Terjadi Covid-19)
Authors:   Pusat Riset Kesejahteraan Sosial Desa dan Konektivitas, Badan Riset dan Inovasi Nasional (BRIN), Suryani Suryani , Raharjo Tyas Eko Raharjo F , Andari Soetji
Published: February 2024

Selama pandemi COVID-19, situasi sulit melanda Indonesia dan dunia secara luas. Banyak negara yang terkena dampak gelombang virus ini, yang menyebabkan ketidakstabilan ekonomi. Oleh karena itu, penelitian ini mencoba menjawab pertanyaan tentang bagaimana kearifan lokal dapat digunakan untuk memberikan layanan sosial kepada masyarakat selama pandemi COVID-19. Tujuan penelitian ini adalah untuk memahami peran kearifan lokal dalam menyediakan pelayanan kesejahteraan sosial bagi Masyarakat. Tujuan penelitian ini yakni mengetahui kearifan lokal dalam memberikan pelayanan kesejahteraan sosial bagi masyarakat. Lokasi penelitian dilaksanakan di Kabupaten Gunungkidul dan Kabupaten Kulonprogo. Metode yang digunakan yaitu pendekatan kualitatif. Kearifan lokal yang dapat didayagunakan dalam mengatasi kelangsungan hidup pada saat pandemi COVID-19 meliputi pengetahuan lokal, budaya lokal, keterampilan lokal, sumber daya lokal, proses sosial, dan solidaritas kelompok. Hasil penelitian menunjukkan bahwa kearifan lokal tersebut dapat bermanfaat bagi masyarakat dalam memberikan layanan kesejahteraan sosial saat pandemi COVID-19. Di Kabupaten Gunungkidul berdasarkan pengetahuan sosial masih kental dengan tradisi jimpitan. Hasil dari kegiatan tersebut setelah terkumpul dapat dipergunakan untuk membantu warga masyarakat yang terdampak COVID-19. Sedangkan di Kabupaten Kulonprogo muncul istilah jogo tonggo istilah dalam bahasa jawa yang mengandung makna menjaga antartetangga. Oleh karena itu dalam kehidupan bermasyarakat, selalu ada semangat saling memberi dan menolong antara sesama tetangga. Selain hal tersebut masih ada tradisi-tradisi yang dapat digunakan sebagai alat dalam memberikan layanan bagi warga yakni sifat gotongroyong yang selalu ada di dua lokasi tersebut. Sifat gotongroyong yang sampai saat ini masih dipertahankan. Rekomendasi perlu adanya kerjasama di antara pemerintah setempat dengan warga dalam melestarikan budaya lokal maupun tradisi yang dianggap dapat memberikan pertolongan bagi warga masyarakat pada saat wabah COVID-19 menyebar.
Death – (Re)Birth, Image – Setting: Symbiotic Relationships in a Byzantine Rock-Cut Church
Authors: Mathiesen Sarah
Published: February 2024

Dated to the late ninth century, scholars position the rock-cut church Yılanlı Kilise as an idiosyncratic outlier, representative of non-Byzantine influence, within Byzantine Cappadocia. I suggest scholars overemphasize Yılanlı’s oddities and underemphasize the complex programmatic and liturgical conception behind Yılanlı and its relation to eleventh-century, Constantinopolitan-influenced Cappadocian churches. I present a case study centered on the interaction between the Koimesis of the Theotokos and a carved water basin that demonstrates that the church’s furniture and images constitute a symbiotic relationship that amplifies and extends their function and meaning. The Yılanlı Koimesis notably includes the Jew Jephonias. Located below the Theotokos’s bed, Jephonias raises arms with severed hands in an orant-like gesture while his body breaches the image border to touch the water basin below. By representing Jephonias without hands, the Yılanlı program purposefully displays the moment after Jephonias is punished for attempting to upset the bier of the Theotokos but before the subsequent recovery of his hands and “rebirth” as a Christian. The presence of Jephonias both creates a narrative image with a supersessionist conversion message and identifies the basin’s baptismal function; simultaneously, the completion of the Jephonias episode is only activated due to his proximity to the baptismal basin.
Basic life support knowledge among nurses at public health center in rural Banten Province, Indonesia
Authors: Sasmito Priyo , Mikawati Mikawati , Prasetya Fika Indah , Syafridawita Yetti , Purwanti Nunuk Sri , Tafwidhah Yuyun , Santoso Mochamad Budi , Arifani Nisa
Published: February 2024

Background: Public Health Center (PHC) is one of the primary healthcare facilities that has an important role in the chain of survival of out-of-hospital cardiac arrest (OHCA) patients, especially in rural areas. Nurses are an important component of health workers in PHC. Basic Life Support (BLS) knowledgeis the basic component of building a qualified resuscitation.Purpose: To analyze the relationship between demographic characteristics of PHC’s nurses in a rural area and their knowledge about BLS.Method: An observational analytical study with a cross-sectional approach involved 32 PHC nurses with total sampling techniques. The data was analyzed with the Spearman Rho and Fisher Exact test.Results: 32 nurses were involved. Most respondents are male (18/56.25%), have a Diploma educational background (23/71.88%), and non-government employees (24/75%). The average age of respondents was 34.75 years, and the average worked for 9.25 years. The level of knowledge of BLS was mostly more than 56% (25/78.1%). The knowledge average was 74.06+ 8.93 with a median of 75 anda score range of 50-85. Gender, educational background, BLS certificate upgrades, and employment status were not related to the level of knowledge of BLS. Age and length of work variables have a significant correlation with knowledge. Calculated rs was -0.043 with a p-value of 0.008 (α 0.05) for age and rs value of -0.353 with a p-value of 0.024 (α 0.05) for length of work.Conclusion: Gender, educational background, BLS certificate upgrades, and employment status were not related to the level of knowledge of BLS.There is a sufficient and significant relationship between the age and length of workwith knowledge of BLS with the opposite direction of the relationship.The older and longer a nurseworks, the lowerthe nurse’s knowledge of BLS.  Routine BLS training sessions or emergency drills in PHC both online and offline can be some solution in partnership with emergency organizations and nearby referral hospitals.
Education intervention model on clean and healthy living habits among mothers having children less than 2 years of age border in remote areas, Indonesia
Authors: Gustina Mely , Ali Haidina , Bathari Rosalia Rina , Hendryani Atika , Rahmawati Ullya
Published: February 2024

Background: Stunting in toddlers reflects a failure to grow due to nutritional deficiencies. Repeated exposure to fecal pathogens, especially prevalent in areas where open defecation practices exist, can lead to diarrhea, hindered growth, health issues, and irreversible developmental impairments.Purpose: To determine the effectiveness of Agamis Sistematis Interaktif Kreatif/ASIK (Religious, Systematic, Interactive, Creative) education model (focusing on water, sanitation, and hygiene) on clean and healthy living habit (CHLH) among toddlers at risk of stunting in the remote border areas of Enggano Island, Bengkulu Province in 2023.Method: The researcher employed a non-equivalent control group design, also known as a pre-test post-test control group design, for the experimental and control groups. This research involved a sample of 60 mothers having children less than 2 years of age, comprising 30 in the intervention group and 30 in the control group. Data collection utilized a questionnaire. Univariate and bivariate data analysis was conducted using the paired t-test statistical analysis. The results of this study revealed a difference in the mean values between the experimental and control groups concerning WAZ (weight-for-age z-scores), with values in the experimental group pre=72.7000, post=75.2667, and the control group pre=76.8167, post=78.4167.Results: The research findings indicated a difference in CHLH between the treatment and control groups (ρ=0.000, ρ<0.05). The ASIK education model on CHLH among toddlers at risk of stunting is effectively applicable in the remote border areas of Enggano Island, Bengkulu Province in 2023.Conclusion: Government support in the form of budget allocation is crucial for the sustainability of continuous education aimed at stunting prevention in village communities.
ФОРМУВАННЯ ЕКОЛОГІЧНОГО МИСЛЕННЯ ЗДОБУВАЧІВ В УМОВАХ ПРОФЕСІЙНОЇ ПІДГОТОВКИ
Authors: Олександренко К.
Published: February 2024

У статті на за результатами аналізу уявлень респондентів сформульовано показники вимірювання ефективності формування екологічного мислення через еко-спільноти та його моніторингу в умовах професійної підготовки. Результати дослідження дозволяють стверджувати, що утворення екологічних спільнот надає можливість заповнити дефіцит знань у царині охорони довкілля та підготувати здобувачів до вибору найменш ворожих щодо довкілля шляхів розв'язання власних проблем і задоволення власних потреб.
Pengaruh Penerapan Pendekatan STEAM Terhadap Kemampuan Berpikir Kreatif Siswa Kelas IV SD
Authors: Atang Sutisna  , Nova Aryanti  , Dadang Cunandar
Published: February 2024

Tujuan penelitian ini adalah untuk mengetahui pengaruh penerapan pendekatan STEAM terhadap kemampuan berpikir kreatif siswa di kelas IV SD Negeri 1 Jalaksana. Metode dalam penelitian ini adalah metode penelitian Quasi Experiment Design dengan desain Nonequivalent Control Group Design. Populasi penelitiannya adalah seluruh siswa kelas IV SD Negeri 1 Jalaksana yang berjumlah 57 siswa. Sampelnya adalah kelas IV A sebagai kelas kontrol yang berjumlah 29 siswa dan kelas IV B sebagai kelas eksperimen yang berjumlah 28 siswa. Instrumen dalam penelitian ini adalah tes kemampuan berpikir kreatif berupa pre-test dan post-test sebanyak 10 soal. Hasil penelitian menunjukkan bahwa pembelajaran dengan pendekatan STEAM berpengaruh terhadap kemampuan berpikir kreatif siswa. Hal ini dibuktikan dengan diperolehnya hasil hipotesis Sig. (2-tailed) = 0,000 < 0,05 maka H1 diterima, yang artinya terdapat pengaruh pembelajaran dengan pendekatan STEAM terhadap kemampuan berpikir kreatif siswa di kelas IV SD Negeri 1 Jalaksana
THE EFFECT OF IMMERSIVE TECHNOLOGY ON ENHANCING STUDENT LEARNING:
Authors: Nastiti Kharisma Alivia , Santoso Harry Budi , Junus Kasiyah , Ahmad Mubarik , Purwandari Endina Putri
Published: February 2024

Education is one of the fundamental factors influencing national development. Educators are required to constantly explore the newest and creative strategies to deliver topics to students and promote students’ engagement in the learning process. One technology that has numerous potentials to facilitate the education process is immersive technology. Immersive technology has the potential to improve student achievement by enabling better learning outcomes. This study aims (1) to analyze the trends and impact of immersive technology usage in education; (2) to identify immersive technology that supports students’ learning processes in the pandemic era; and (3) to identify the usage of learning theories in educational application development that implement immersive technology to enhance students’ learning outcomes. This study examined seventeen selected studies after adopting the selection process of the systematic literature review process by Kitchenham. The selected studies were published between 2018 and 2022 by Emerald Insight, IEEE Xplore, and Scopus. There are three kinds of immersive technology identified in this study: virtual reality, augmented reality, and mixed reality. The study showed the nine types of students’ learning outcomes, and the results showed that using immersive technology significantly improved student learning compared to traditional methods. Furthermore, thirteen learning theories were adopted as the basis for developing educational applications. Future research directions are also suggested to continue developing promising and limited new technologies to enhance the variety of education-oriented applications. Immersive technologies designed for learning are still on a long journey, including considerations of readiness and potential effects that may arise for users such as privacy and security concern.
Effect of High-Power Laser Cleaning for Surface Contaminants Removal on SS304L
Authors: Choi Soojin , Yoo Hyun Jong , Choi Jiyeon , Noh Jiwhan , Kang Heeshin , Ahn Sanghoon , Park Junsu , Choi Philgong , Kim Dohyun , Kim Yeonggyu , Kim Byeongju , Jeon Ikgeun , Kim Jeng O , Sohn Hyonkee , Kim Kyunghan , Park Changkyoo
Published: February 2024

In this study, artificially formed corrosion and paint layers on 304L stainless steel (SS304L) specimen were removed using a kilowatt level high-power Nd:YAG laser. A laser power of 1140 W and a pulse duration of 89 ns were used for the corrosion removal, and a laser power of 850 W and a pulse duration of 54 ns were adopted for the paint removal. Surface composition was analyzed via electron probe micro-analysis (EPMA) and x-ray diffraction (XRD) analysis before and after the laser cleaning process, confirming that the corrosion and paint layers were successfully removed from the SS304L surface by the laser cleaning process. The effect of the laser cleaning process on the mechanical properties of SS304L was investigated. The hardness and tensile strength of the laser-cleaned specimens were analyzed to determine their mechanical properties. After the laser cleaning process, the surface hardness was slightly increased up to depths of 250 µm for the corrosion removal and up to 50 µm for the paint removal. However, only marginal changes in tensile strength and elongation were detected after the laser cleaning process. These results confirmed that laser cleaning can effectively remove surface contaminants (i.e., corrosion and paint) on SS304L with only a minimum modification of microstructure and mechanical properties.
GAMBARAN TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN KEFARMASIAN DI APOTEK EMPUNALA PERIODE MARET – MEI 2023
Authors: Priyoherianto Andri , Fitriany Erna , Legowo Deny Budi , Arif M. Rizky
Published: February 2024

Pharmaceutical services are health services that have an important role in realizing health quality. Pharmaceutical services apart from being a 2 demand for professionalism such as a factor that attracts consumers' interest in purchasing drugs at pharmacies in order to obtain patient satisfaction. The purpose of this study was to describe the level of patient satisfaction with pharmaceutical services at the Empunala Drug store and to improve the quality of pharmaceutical services at the Empunala Drug store. This Research is descriptive non-experimental with incidental sampling, data collection using a questionnaire. The results of the study on the level of patient satisfaction with pharmaceutical services at the Empunala Drug store period March until May 2023 concluded on the Reliability dimension is 76%, the Responsiveness dimension is 78%, the Assurance dimension is 78%, the Emphaty dimension is 77%, and the Tangible dimension is 80%.
Att verka som specialpedagog: Ett uppdrag under förhandling
Authors: Franzén Adam , Ek Andersson Jenni , Lindqvist Henrik
Published: February 2024

Specialpedagogens uppdrag och roll innefattar många olika ansvarsområden och arbetsuppgifter. Rektor är den som sätter ramar och därmed också skapar förutsättningar för hur det specialpedagogiska arbetet ska utformas på den skola där specialpedagogen är verksam. Det verkar vanligt att specialpedagoger själva är med och skriver sina egna arbetsbeskrivningar. Specialpedagogers uppdrag kan därmed komma att bli format i förhandlingen som sker mellan rektor och specialpedagog. Denna artikel tar utgångspunkt i ett examensarbete av Franzén och Ek Andersson (2023) för att diskutera rollen som en specialpedagog kan få på en skola.
A/R/TOGRAFIAS: CORPOS DANÇANTES, DOCENTES PESQUISADORES EM FORMAÇÃO
Authors: Carvalho Carla , Souza Marco Aurélio da Cruz
Published: February 2024

Este artigo tem como objetivo refletir sobre aspectos que se entreleçam no processo de formação de um artista, professor, pesquisador na área da dança. É um estudo qualitativo que analisa três pesquisas a/r/tográficas realizadas num curso de formação em licenciatura em dança numa universidade brasileira. Faz parte dos estudos do GP Arte e Estética na Educação. Os trabalhos foram selecionados segundo três critérios: ser a/r/tografia; refletir sobre processos com estudantes; e ter relação com a educação básica. Os dados indicam que, nesse processo, a a/r/tografia, como metodologia de pesquisa, possibilitou que as pesquisadoras se deparassem frente aos dados e, com eles se percebessem criadoras de seu processo de pesquisa, de docência e de arte. A a/r/tografia foi reconhecida como prática de criação intencional na relação com a pesquisa, aspecto que já estava presente em suas práticas artí­sticas e docentes. Ainda, pode-se afirmar a potência da a/r/tografia na formação nas licenciaturas em arte numa relação entre a pesquisa e o processo de formação docente, o que afirma a condição da pesquisa enquanto princí­pio de educativo.
PISTAS PARA UM TEATRO DE IMERSÃO NA CRIAÇÃO DO ESPETÁCULO RÉSTIAS DE HISTÓRIAS [OU] NA SOLIDÃO DE UMA CASA IMENSA
Authors: Paulino Walkiria Presa , Carraro Cristóvão Oliveira
Published: February 2024

O presente artigo apresenta uma reflexão sobre o teatro de imersão a partir da experiência de criação do espetáculo Réstias de Histórias [ou] Na solidão de uma casa imensa do Núcleo de Intermitências Teatrais. Esse estudo foi realizado a partir da minha participação como criadora neste coletivo teatral e como pesquisadora no projeto de Iniciação Cientí­fica (PIC). No texto realizam-se descrições do processo criativo do grupo em aproximação com teorias sobre a criação da obra de arte de Cecí­lia Almeida Salles e a relação do público com a obra de arte a partir de autores como Nicolas Bourriaud, Jacques Rancière, John Dewey e Umberto Eco. O estudo passa por três importantes pontos da criação do espetáculo sendo o primeiro a imersão de artistas criadores no processo, o segundo a imersão na obra do escritor Gabriel Garcí­a Márquez e o terceiro a imersão como poética do espetáculo teatral. Nesse último considero alguns parâmetros norteadores para a construção de um espetáculo imersivo como a dramaturgia aberta, a democratização do espaço cênico e a atuação em diferentes camadas. Posteriormente o texto traz apontamentos sobre a organicidade entre processo criativo e obra final.PALAVRAS-CHAVE: Teatro imersivo; Arte relacional; Processo criativo; Processo colaborativo.
"A partilha do sensível" : arte e vida nos encontros de arte moderna e nos domingos de criação
Authors: HAUPTMAN CARDOSO DE OLIVEIRA LUANA
Published: February 2024

Durante a década de 1960-70 alguns eventos e propostas artí­sticas foram realizados a partir de uma estética de aproximação entre arte e vida. Em meio a um perí­odo conturbado e de censura da cultura no paí­s, a arte, em diálogo com as movimentações artí­sticas internacionais e na resistência ao regime militar, construiu-se em meio a questões artí­sticas e polí­ticas ou como Jacques Rancière conceituou, uma "partilha do sensí­vel" . Neste contexto, este artigo analisa dois eventos: os Encontros de Arte Moderna idealizados pela crí­tica de arte Adalice Araújo, em Curitiba e os Domingos de criação, proposta do crí­tico Frederico Morais que aconteceram no Rio de Janeiro. A aproximação desses eventos tem por objetivo refletir sobre como as discussões da arte de vanguarda brasileira produziram ecos distintos nas diferentes localidades a partir de um programa artí­stico que propôs a transformação do sensí­vel na arte e na sociedade através da renovação das práticas artí­sticas e da inserção dos sujeitos invisibilizados no processo de produção e apreciação da arte.
Dando tempo ao tempo: experiências com o tempo na prática teatral pandêmica online
Authors: De Paula Macedo Angela Stadler
Published: February 2024

Relato de pesquisa prático-teórica que investigou o tempo e alguns de seus vocábulos adjacentes, e procurou estabelecer relações entre conceitos e experimentos sencientes. Isto se deu através da consonância de experiências em laboratórios tecnovivos Dubátticos, com base no conceito de duração de Henri Bergson, e seus princípios pragmáticos. Uma principal questão delineou a investigação: Como ideias sobre o tempo influenciam performers em experimento de ação? Assim, procurei compreender as interferências temporais em corpos actantes, tendo como registro as reflexões dialógicas entre conceitos e atos, em processos concomitantes. Como objetivo da pesquisa, intencionei apreender uma compreensão mais profunda sobre a temática apresentada, assimilando as aplicações práticas em laboratório, sobre a qual esta investigação foi pavimentada – um tempo que constrói, instiga, promove e causa acontecimentos na ação elaborada. A pesquisa justifica-se em seu caráter pedagógico, tendo a pedagogia da experiência como viés ideológico; a apresentação se dá através de uma escrita performática, com sua poesia inspirada pela forma dramática.
Can arctic migrants adjust their phenology based on temperature encountered during the spring migration? The case of the greater snow goose
Authors: Reséndiz-Infante Cynthia , Gauthier Gilles
Published: February 2024

The reproductive phenology of many long-distance migrants breeding at high latitudes remains unresponsive or responds only slightly to climate warming. In order to adjust migration speed and arrival time on the breeding grounds, environmental cues encountered during the migration must be related to conditions prevailing at the breeding site. However, heterogeneity in rate of climate warming across latitudes may hamper the ability of birds to adjust their migration speed adequately. We examined to what extent temperatures encountered at stopovers were a good predictor of temperatures at subsequent stopovers and at the breeding site in greater snow geese (Anser caerulescens atlanticus), an Arctic species that showed little change in its breeding phenology over the past 3 decades. We also examined temperature trends at various stopovers used by geese and at the breeding site over a 40-year period. We found that warming was stronger at the Arctic stopovers and the breeding site than at southern staging areas. The mean temperature and rate of temperature change encountered at the southern stopover, where this species accumulates most of its body reserves, was weakly correlated to temperatures prevailing at more northern stopovers and the breeding site located 3,000 km further north. Correlations in temperatures between stopovers and the breeding site increased with decreasing distance between sites and as geese moved further north. Lastly, laying date was strongly related to temperature during the arrival and pre-laying period on the breeding grounds but not to temperatures encountered at stopovers during migration. Temperatures encountered along the migratory route are thus a poor predictor of temperatures prevailing at the breeding site in any given year except when geese are getting close to their breeding grounds. This may be a major constraint preventing geese from adjusting their migratory schedule to conditions on their breeding grounds and may explain why their reproductive phenology did not change despite a warming trend at the breeding site.
Next-generation direct reprogramming
Authors: Keshri Riya , Detraux Damien , Phal Ashish , McCurdy Clara , Jhajharia Samriddhi , Chan Tung Ching , Mathieu Julie , Ruohola-Baker Hannele
Published: February 2024

Tissue repair is significantly compromised in the aging human body resulting in critical disease conditions (such as myocardial infarction or Alzheimer’s disease) and imposing a tremendous burden on global health. Reprogramming approaches (partial or direct reprogramming) are considered fruitful in addressing this unmet medical need. However, the efficacy, cellular maturity and specific targeting are still major challenges of direct reprogramming. Here we describe novel approaches in direct reprogramming that address these challenges. Extracellular signaling pathways (Receptor tyrosine kinases, RTK and Receptor Serine/Theronine Kinase, RSTK) and epigenetic marks remain central in rewiring the cellular program to determine the cell fate. We propose that modern protein design technologies (AI-designed minibinders regulating RTKs/RSTK, epigenetic enzymes, or pioneer factors) have potential to solve the aforementioned challenges. An efficient transdifferentiation/direct reprogramming may in the future provide molecular strategies to collectively reduce aging, fibrosis, and degenerative diseases.
Antibody responses to Chlamydia trachomatis vaccine candidate antigens in Chlamydia-infected women and correlation with antibody-mediated phagocytosis of elementary bodies
Authors: Yu Hong , Geisler William M. , Dai Chuanbin , Gupta Kanupriya , Cutter Gary , Brunham Robert C.
Published: February 2024

Murine research has revealed a significant role for antibody responses in protection against Chlamydia reinfection. To explore potential humoral immune markers of protection elicited by Chlamydia trachomatis (CT) antigens in humans in the context of presumed clinical correlates of protection, we used both an IgG1-based ELISA and a conventional total IgG ELISA to evaluate antibody responses. We evaluated responses to five CT outer membrane proteins (PmpE, PmpF, PmpG, PmpH, and MOMP), along with other promising CT antigens (Pgp3 and HSP60), negative control antigens (RecO and AtpE), and CT elementary bodies (EBs) in sera from a well-characterized cohort of 60 women with different CT infection outcomes, including two outcomes that are likely clinical correlates of protective immunity: spontaneous resolution of infection and absence of reinfection after treatment. Furthermore, we used a flow cytometry-based assay to measure antibody-mediated phagocytosis by neutrophils in these sera. Results demonstrated that IgG1 ELISA displayed higher sensitivity than conventional total IgG ELISA in assessing antibody responses to CT EBs and antigens. Pgp3 IgG1 ELISA exhibited the highest sensitivity compared to IgG1 ELISA incorporating CT EBs or other antigens, confirming Pgp3 IgG1 ELISA as an ideal assay for CT antibody detection. Most (95%) sera from women with CT infection outcomes exhibited antibody-mediated phagocytosis of CT EBs, which was significantly correlated with IgG1 antibody responses to MOMP, Pgp3, HSP60, and PmpF. However, neither IgG1 responses to CT antigens and EBs nor antibody-mediated phagocytosis were associated with clinical correlates of protection. These findings suggest that neither CT IgG1 antibody detection nor antibody-mediated phagocytosis will be useful as immune correlates of protection against CT infection in humans.
Alternative in-vivo models of mucormycosis
Authors: Scheler Jakob , Binder Ulrike
Published: February 2024

Mucormycosis is still regarded a rare fungal infection, but the high incidences of COVID-associated cases in India and other countries have shown its potential threat to large patient cohorts. In addition, infections by these fast-growing fungi are often fatal and cause disfigurement, badly affecting patients’ lives. In advancing our understanding of pathogenicity factors involved in this disease, to enhance the diagnostic toolset and to evaluate novel treatment regimes, animal models are indispensable. As ethical and practical considerations typically favor the use of alternative model systems, this review provides an overview of alternative animal models employed for mucormycosis and discusses advantages and limitations of the respective model.
Individualized post-crisis monitoring of psychiatric patients via Hidden Markov models
Authors: Garriga Roger , Gómez Vicenç , Lugosi Gábor
Published: February 2024

Introduction

Individuals in the midst of a mental health crisis frequently exhibit instability and face an elevated risk of recurring crises in the subsequent weeks, which underscores the importance of timely intervention in mental healthcare. This work presents a data-driven method to infer the mental state of a patient during the weeks following a mental health crisis by leveraging their historical data. Additionally, we propose a policy that determines the necessary duration for closely monitoring a patient after a mental health crisis before considering them stable.

Methods

We model the patient’s mental state as a Hidden Markov Process, partially observed through mental health crisis events. We introduce a closed-form solution that leverages the model parameters to optimally estimate the risk of future mental health crises. Our policy determines a patient should be closely monitored when their estimated risk of crisis exceeds a predefined threshold. The method’s performance is evaluated using both simulated data and a real-world dataset comprising 162 anonymized psychiatric patients.

Results

In the simulations, 96.2% of the patients identified by the policy were in an unstable state, achieving a F1 score of 0.74. In the real-world dataset, the policy yielded an F1 score of 0.79, with a sensitivity of 79.8% and specificity of 88.9%. Under this policy, 67.3% of the patients should undergo close monitoring for one week, 21.6% during 2 weeks or more, while 11.1% do not need close monitoring.

Discussion

The simulation results provide compelling evidence that the method is effective under the specified assumptions. When applied to actual psychiatric patients, the proposed policy showed significant potential for providing an individualized assessment of the required duration for close and automatic monitoring after a mental health crisis to reduce the relapse risks.
Feasibility analysis of hybrid energy generation systems for desert highway service areas: a case study in northern Xinjiang, China
Authors: Wang Guangtao , Zhang Yufei , Tang Wenbin , Liao Zhen , Wang Teng , Zhang Shuo , Zhao Xin
Published: February 2024

Highways consume a significant amount of electrical energy annually, especially in remote desert regions where the cost of electricity is high. This research explores the utilization of natural resources along desert highways to establish hybrid energy generation systems for service areas. Three service areas along the desert highway in northern Xinjiang, China, serve as case studies. To assess the feasibility of hybrid energy generation systems in these service areas, meteorological data for the three locations were obtained from the NASA platform. The HOMER Pro software was employed for technical, economic, and environmental analyses of the systems. The results indicate the feasibility of Photovoltaic (PV)/Wind/Battery hybrid energy systems in the Huanghuagou, Kelameili, and Wujiaqu service areas. The application of these hybrid energy generation systems across the three service areas could provide 3,349,557 kWh of electrical energy annually for the desert highway. Sensitivity analysis reveals that the Net Present Cost (NPC) and Cost of Energy (COE) values decrease with increasing radiation levels, while NPC shows an increasing trend with growing load demand, and COE exhibits a decreasing trend. Among the three regions, Wujiaqu demonstrates the highest economic viability, with a COE of $0.34/kWh and an NPC of $3,141,641/kWh. Furthermore, Wujiaqu exhibits the lowest environmental impact, with CO2 emissions of 198,387 kg/yr, SO2 emissions of 493 kg/yr, and NOx emissions of 1,711 kg/yr.
The greatest contribution to medical science is the transformation from studying symptoms to studying their causes—the unrelenting legacy of Robert Koch and Louis Pasteur—and a causality perspective to approach a definition of SLE
Authors: Rekvig Ole Petter
Published: February 2024

The basic initiative related to this study is derived from the fact that systemic lupus erythematosus (SLE) is a unique and fertile system science subject. We are, however, still far from understanding its nature. It may be fair to indicate that we are spending more time and resources on studying the complexity of classified SLE than studying the validity of classification criteria. This study represents a theoretical analysis of current instinctual1 SLE classification criteria based on “the causality principle.” The discussion has its basis on the radical scientific traditions introduced by Robert Koch and Louis Pasteur. They announced significant changes in our thinking of disease etiology through the implementation of the modern version of “the causality principle.” They influenced all aspects of today’s medical concepts and research: the transformation of medical science from studies of symptoms to study their causes, relevant for monosymptomatic diseases as for syndromes. Their studies focused on bacteria as causes of infectious diseases and on how the immune system adapts to control and prevent contagious spreading. This is the most significant paradigm shift in the modern history of medicine and resulted in radical changes in our view of the immune system. They described acquired post-infection immunity and active immunization by antigen-specific vaccines. The paradigm “transformation” has a great theoretical impact also on current studies of autoimmune diseases like SLE: symptoms and their cause(s). In this study, the evolution of SLE classification and diagnostic criteria is discussed from “the causality principle” perspective, and if contemporary SLE classification criteria are as useful as believed today for SLE research. This skepticism is based on the fact that classification criteria are not selected based on cogent causal strategies. The SLE classification criteria do not harmonize with Koch’s and Pasteur’s causality principle paradigms and not with Witebsky’s Koch-derived postulates for autoimmune and infectious diseases. It is not established whether the classification criteria can separate SLE as a “one disease entity” from “SLE-like non-SLE disorders”—the latter in terms of SLE imitations. This is discussed here in terms of weight, rank, and impact of the classification criteria: Do they all originate from “one basic causal etiology”? Probably not.
Pre-transplant donor specific antibodies in ABO incompatible kidney transplantation – data from the Swiss transplant cohort study
Authors: Deng Yun , Frischnknecht Lukas , Wehmeier Caroline , de Rougemont Olivier , Villard Jean , Ferrari-Lacraz Sylvie , Golshayan Déla , Gannagé Monique , Binet Isabelle , Wirthmueller Urs , Sidler Daniel , Schachtner Thomas , Schaub Stefan , Nilsson Jakob
Published: February 2024

Background

Living donor (LD) kidney transplantation in the setting of ABO blood group incompatibility (ABOi) has been previously reported to be associated with increased risk for antibody-mediated rejection (ABMR). It is however unclear if the presence of pre-transplant donor specific antibodies (DSA) works as an additive risk factor in the setting of ABOi and if DSA positive ABOi transplants have a significantly worse long-term outcome as compared with ABO compatible (ABOc) DSA positive transplants.

Methods

We investigated the effect of pre-transplant DSA in the ABOi and ABOc setting on the risk of antibody-mediated rejection (ABMR) and graft loss in a cohort of 952 LD kidney transplants.

Results

We found a higher incidence of ABMR in ABOi transplants as compared to ABOc transplants but this did not significantly affect graft survival or overall survival which was similar in both groups. The presence of pre-transplant DSA was associated with a significantly increased risk of ABMR and graft loss both in the ABOi and ABOc setting. We could not detect an additional risk of DSA in the ABOi setting and outcomes were comparable between DSA positive ABOi and ABOc recipients. Furthermore, a combination of DSA directed at both Class I and Class II, as well as DSA with a high mean fluorescence intensity (MFI) showed the strongest relation to ABMR development and graft loss.

Conclusion

The presence of pre-transplant DSA was associated with a significantly worse long-term outcome in both ABOi and ABOc LD kidney transplants and our results suggests that the risk associated with pre-transplant DSA is perhaps not augmented in the ABOi setting. Our study is the first to investigate the long-term effects of DSA in the ABOi setting and argues that pre-transplant DSA risk could potentially be evaluated similarly regardless of ABO compatibility status.
Towards Human-like Walking with Biomechanical and Neuromuscular Control Features: Personalized Attachment Point Optimization Method of Cable-Driven Exoskeleton
Authors: Chen Yasheng , Yu Weiwei , Benali Abderraouf , Lu Donglai , Kok Siong Yuen , Wang Runxiao
Published: February 2024

The cable-driven exoskeleton can avoid joint misalignment, and is substantial alterations in the pattern of muscle synergy coordination, which arouse more attention in recent years to facilitate exercise for older adults and improve their overall quality of life. This study leverages principles from neuroscience and biomechanical analysis to select attachment points for cable-driven soft exoskeletons. By extracting key features of human movement, the objective is to develop a subject-specific design methodology that provides precise and personalized support in the attachment points optimization of cable-driven exoskeleton to achieve natural gait, energy efficiency, and muscle coordination controllable in the domain of human mobility and rehabilitation. To achieve this, the study first analyzes human walking experimental data and extracts biomechanical features. These features are then used to generate trajectories, allowing better natural movement under complete cable-driven exoskeleton control. Next, a genetic algorithm-based method is employed to minimize energy consumption and optimize the attachment points of the cable-driven system. This process identifies connections that are better suited for the human model, leading to improved efficiency and natural movement. By comparing the calculated elderly human model driven by exoskeleton with experimental subject in terms of joint angles, joint torques and muscle forces, the human model can successfully replicate subject movement and the cable output forces can mimic human muscle coordination. The optimized cable attachment points facilitate more natural and efficient collaboration between humans and the exoskeleton, making significant contributions to the field of assisting the elderly in rehabilitation.