bluuebunny/crossref_metadata_2025 huggingface dataset:
Change of urban park usage as a response to the COVID-19 global pandemic
Authors: Zhao Haokai , Mailloux Brian J. , Cook Elizabeth M. , Culligan Patricia J.
Published: November 2023

Urban parks became critical for maintaining the well-being of urban residents during the COVID-19 global pandemic. To examine the impact of COVID-19 on urban park usage, we selected New York City (NYC) and used SafeGraph mobility data, which was collected from a large sample of mobile phone users, to assess the change in park visits and travel distance to a park based on 1) park type, 2) the income level of the visitor census block group (visitor CBG) and 3) that of the park census block group (park CBG). All analyses were adjusted for the impact of temperature on park visitation, and we focused primarily on visits made by NYC residents. Overall, for the eight most popular park types in NYC, visits dropped by 49.2% from 2019 to 2020. The peak reduction in visits occurred in April 2020. Visits to all park types, excluding Nature Areas, decreased from March to December 2020 as compared to 2019. Parks located in higher-income CBGs tended to have lower reductions in visits, with this pattern being primarily driven by large parks, including Flagship Parks, Community Parks and Nature Areas. All types of parks saw significant decreases in distance traveled to visit them, with the exception of the Jointly Operated Playground, Playground, and Nature Area park types. Visitors originating from lower-income CBGs traveled shorter distances to parks and had less reduction in travel distances compared to those from higher-income CBGs. Furthermore, both before and during the pandemic, people tended to travel a greater distance to parks located in high-income CBGs compared to those in low-income CBGs. Finally, multiple types of parks proved crucial destinations for NYC residents during the pandemic. This included Nature Areas to which the visits remained stable, along with Recreation Field/Courts which had relatively small decreases in visits, especially for lower-income communities. Results from this study can support future park planning by shedding light on the different uses of certain park types before and during a global crisis, when access to these facilities can help alleviate the human well-being consequences of “lockdown” policies.
Leveraging global climate models to assess multi-year hydrologic drought
Authors: Vieira Michael J. F. , Stadnyk Tricia A.
Published: November 2023

Global climate models (GCMs) offer value for assessments of future water supply and multi-year hydrologic drought. Leveraging GCM data, we develop and analyze global scenarios of mean annual runoff over a span of 640 years. Runoff data from eighteen GCMs are evaluated for skill and bias-adjusted to reflect observations. Unprecedented projections of mean runoff, drought severity, and drought duration are found for 37%, 28%, and 23% of analyzed global land area, respectively, with regions on all continents presenting a risk of a drier future. Conversely, northern latitudes show evidence of increasing runoff, less severe, and shorter-duration droughts. Outside these regions, projections are either indistinguishable from internal climate variability or unreliable due to conflicting signal-to-noise ratios and ensemble agreement. Our analysis contributes to a global gap in understanding future multi-year hydrologic droughts, which can pose significant socio-economic risks.
Predictive analytics for cardio-thoracic surgery duration as a stepstone towards data-driven capacity management
Authors: Nikolova-Simons Mariana , Keldermann Rikkert , Peters Yvon , Compagner Wilma , Montenij Leon , de Jong Ymke , Bouwman R. Arthur
Published: November 2023

Effective capacity management of operation rooms is key to avoid surgery cancellations and prevent long waiting lists that negatively affect clinical and financial outcomes as well as patient and staff satisfaction. This requires optimal surgery scheduling, leveraging essential parameters like surgery duration, post-operative bed type and hospital length-of-stay. Common clinical practice is to use the surgeon’s average procedure time of the last N patients as a planned surgery duration for the next patient. A discrepancy between the actual and planned surgery duration may lead to suboptimal surgery schedule. We used deidentified data from 2294 cardio-thoracic surgeries to first calculate the discrepancy of the current model and second to develop new predictive models based on linear regression, random forest, and extreme gradient boosting. The new ensamble models reduced the RMSE for elective and acute surgeries by 19% (0.99 vs 0.80, p = 0.002) and 52% (1.87 vs 0.89, p < 0.001), respectively. Also, the elective and acute surgeries “behind schedule” were reduced by 28% (60% vs. 32%, p < 0.001) and 9% (37% vs. 28%, p = 0.003), respectively. These improvements were fueled by the patient and surgery features added to the models. Surgery planners can benefit from these predictive models as a patient flow AI decision support tool to optimize OR utilization.
Eigenmode-based approach reveals a decline in brain structure–function liberality across the human lifespan
Authors: Yang Yaqian , Tang Shaoting , Wang Xin , Zhen Yi , Zheng Yi , Zheng Hongwei , Liu Longzhao , Zheng Zhiming
Published: November 2023

While brain function is supported and constrained by the underlying structure, the connectome-based link estimated by current approaches is either relatively moderate or accompanied by high model complexity, with the essential principles underlying structure-function coupling remaining elusive. Here, by proposing a mapping method based on network eigendecomposition, we present a concise and strong correspondence between structure and function. We show that the explanation of functional connectivity can be significantly improved by incorporating interactions between different structural eigenmodes. We also demonstrate the pronounced advantage of the present mapping in capturing individual-specific information with simple implementation. Applying our methodology to the human lifespan, we find that functional diversity decreases with age, with functional interactions increasingly dominated by the leading functional mode. We also find that structure-function liberality weakens with age, which is driven by the decreases in functional components that are less constrained by anatomy, while the magnitude of structure-aligned components is preserved. Overall, our work enhances the understanding of structure-function coupling from a collective, connectome-oriented perspective and promotes a more refined identification of functional portions relevant to human aging, holding great potential for mechanistic insights into individual differences associated with cognition, development, and neurological disorders.
Synaptic proteasome is inhibited in Alzheimer’s disease models and associates with memory impairment in mice
Authors: Ribeiro Felipe C. , Cozachenco Danielle , Heimfarth Luana , Fortuna Juliana T. S. , de Freitas Guilherme B. , de Sousa Jorge M. , Alves-Leon Soniza V. , Leite Renata E. P. , Suemoto Claudia K. , Grinberg Lea T. , De Felice Fernanda G. , Lourenco Mychael V. , Ferreira Sergio T.
Published: November 2023

The proteasome plays key roles in synaptic plasticity and memory by regulating protein turnover, quality control, and elimination of oxidized/misfolded proteins. Here, we investigate proteasome function and localization at synapses in Alzheimer’s disease (AD) post-mortem brain tissue and in experimental models. We found a marked increase in ubiquitinylated proteins in post-mortem AD hippocampi compared to controls. Using several experimental models, we show that amyloid-β oligomers (AβOs) inhibit synaptic proteasome activity and trigger a reduction in synaptic proteasome content. We further show proteasome inhibition specifically in hippocampal synaptic fractions derived from APPswePS1ΔE9 mice. Reduced synaptic proteasome activity instigated by AβOs is corrected by treatment with rolipram, a phosphodiesterase-4 inhibitor, in mice. Results further show that dynein inhibition blocks AβO-induced reduction in dendritic proteasome content in hippocampal neurons. Finally, proteasome inhibition induces AD-like pathological features, including reactive oxygen species and dendritic spine loss in hippocampal neurons, inhibition of hippocampal mRNA translation, and memory impairment in mice. Results suggest that proteasome inhibition may contribute to synaptic and memory deficits in AD.
ASMT determines gut microbiota and increases neurobehavioral adaptability to exercise in female mice
Authors: Liu Weina , Huang Zhuochun , Zhang Ye , Zhang Sen , Cui Zhiming , Liu Wenbin , Li Lingxia , Xia Jie , Zou Yong , Qi Zhengtang
Published: November 2023

N-acetylserotonin O-methyltransferase (ASMT) is responsible for melatonin biosynthesis. The Asmt gene is located on the X chromosome, and its genetic polymorphism is associated with depression in humans. However, the underlying mechanism remains unclear. Here, we use CRISPR/Cas9 to delete 20 bp of exon 2 of Asmt, and construct C57BL/6J mouse strain with Asmt frameshift mutation (Asmtft/ft). We show that female Asmtft/ft mice exhibit anxiety- and depression-like behaviors, accompanied by an obvious structural remodeling of gut microbiota. These behavioral abnormalities are not observed in male. Moreover, female Asmtft/ft mice show a lower neurobehavioral adaptability to exercise, while wild-type shows a “higher resilience”. Cross-sectional and longitudinal analysis indicates that the structure of gut microbiota in Asmtft/ft mice is less affected by exercise. These results suggests that Asmt maintains the plasticity of gut microbiota in female, thereby enhancing the neurobehavioral adaptability to exercise.
Reminders of Japanese redress increase Asian American support for Black reparations
Authors: Kraus Michael W. , Vinluan A. Chyei
Published: November 2023

Informational interventions can shape policy attitudes, and in this study, we examined whether largely unknown information about past reparations payments toward one minoritized group would shape current policy judgments. In 1942, the U.S. government wrongfully relocated and imprisoned more than 120,000 Japanese Americans. In 1988, the government apologized and offered $20,000 USD in reparations payments. Japanese American redress is a recent, but not widely known, concrete example of communities who have successfully fought for reparative economic action. In two preregistered studies of online crowdsourced panels of Asian Americans (N = 329, N = 500), an intervention that raised awareness of this history of incarceration and redress increased support for reparations for Black Americans, relative to a control condition, and national polling data on support for reparations. Exploratory analyses revealed that the degree of learning about Japanese American redress in the intervention explained its impact on support for Black reparations. Future research should target representative samples to understand how education about past redress within one’s own social group affects support for reparative economic justice for others.
Antiepileptic drug concentration detection based on Raman spectroscopy and an improved snake optimization-convolutional neural network algorithm
Authors: Fu Xinghu , Cao Xiqing , Fu Zizhen , Huang Zhexu , Jin Wa , Fu Guangwei , Bi Weihong
Published: November 2023

A method for measurement of antiepileptic drug concentrations based on Raman spectroscopy and an optimization algorithm for mathematical models are proposed and investigated.
Advances in biomedical systems based on microneedles: design, fabrication, and application
Authors: Wang Xinghao , Wang Zifeng , Xiao Min , Li Zhanhong , Zhu Zhigang
Published: November 2023

Microneedle technology advances healthcare with drug release, biosensing and theranostic systems. While promising, issues including production require multidisciplinary efforts to bridge the gap between research and individualized healthcare devices.
Helix-based screening with structure prediction using artificial intelligence has potential for the rapid development of peptide inhibitors targeting class I viral fusion
Authors: Suzuki Satoshi , Kuroda Mio , Aoki Keisuke , Kawaji Kumi , Hiramatsu Yoshiki , Sasano Mina , Nishiyama Akie , Murayama Kazutaka , Kodama Eiichi N. , Oishi Shinya , Hayashi Hironori
Published: November 2023

Peptide inhibitors against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are designed using a screening system for peptide-based inhibitors containing an α-helix region (SPICA) and structures predicted by AlphaFold2.
Mechanistic insights and comparative analysis of Ru(ii)–NNC pincer complexes with anionic-, protic-, and classical-NHCs for transfer hydrogenation of ketones
Authors: Nath Shambhu , Yadav Ekta , Raghuvanshi Abhinav , Singh Amrendra K.
Published: November 2023

A series of Ru(ii)–NNC pincer-type complexes bearing anionic-, protic- and classical-NHC ligands are reported. Comparative analysis of catalytic activity in transfer hydrogenation of ketones is investigated both experimentally and computationally.
Automated MUltiscale simulation environment
Authors: Sabadell-Rendón Albert , Kaźmierczak Kamila , Morandi Santiago , Euzenat Florian , Curulla-Ferré Daniel , López Núria
Published: November 2023

AMUSE is a multiscale framework integrating detailed atomistic information on materials and reactions to predict the performance of heterogeneous catalytic full-scale reactors.
1,2-Azolylamidino ruthenium(ii) complexes with DMSO ligands: electro- and photocatalysts for CO2 reduction
Authors: Jennings Murphy , Cuéllar Elena , Rojo Ariadna , Ferrero Sergio , García-Herbosa Gabriel , Nganga John , Angeles-Boza Alfredo M. , Martín-Alvarez Jose M. , Miguel Daniel , Villafañe Fernando
Published: November 2023

Ru(ii) 1,2-azolylamidino-DMSO complexes are herein described. Their electrochemical behavior in CO2 media is consistent with CO2 electrocatalyzed reduction, whereas photocatalytic CO2 reduction experiments lead to CO and trace amounts of formate.
Aggregation-induced emission of cyclometalated rhodium(iii) and iridium(iii) phenylpyridine complexes with ancillary 1,3-diketones
Authors: Kiseleva Marina A. , Churakov Andrei V. , Taydakov Ilya V. , Metlin Mikhail T. , Kozyukhin Sergey A. , Bezzubov Stanislav I.
Published: November 2023

In the solid state, a simple bis-cyclometalated rhodium(iii) complex with 2-phenylpyridine and ancillary benzoyltrifluoroacetone demonstrates enhanced phosphorescence emission compared to a practically non-emissive analogous iridium(iii) complex.
Advances in graphene-based nanoplatforms and their application in Parkinson's disease
Authors: Oz Tuba , Kaushik Ajeet Kumar , Kujawska Małgorzata
Published: November 2023

Graphene and GBNs offer diverse PD management modalities by targeting neurodegeneration, exerting regenerative properties and their use as carriers, biosensors, and imaging agents.
Novel pyrazolo[3,4-d]pyrimidine derivatives: design, synthesis, anticancer evaluation, VEGFR-2 inhibition, and antiangiogenic activity
Authors: Abdelhamed Ahmed M. , Hassan Rasha A. , Kadry Hanan H. , Helwa Amira A.
Published: November 2023

A novel series of 12 pyrazolo[3,4-d]pyrimidine derivatives were created and evaluated in vitro for their antiproliferative activity against the NCI 60 human tumor cell line panel.
Development of a light-responsive fluorinated poly(arylene ether) copolymer containing azobenzene groups in the main polymer chain
Authors: Tkachenko Ihor M. , Kurioz Yuriy I. , Kravchuk Ruslan M. , Tolstov Alexander L. , Glushchenko Anatoliy V. , Nazarenko Vassili G. , Shevchenko Valery V.
Published: November 2023

A novel azo-based polymer with high mechanical and thermal stability is obtained. The polymer exhibits stable birefringence changes, enabling the fabrication of diffraction gratings, showing its potential for various optical applications.
Correction: A super-high brightness and excellent colour quality laser-driven white light source enables miniaturized endoscopy
Authors: Li Shuxing , Huang Linhui , Guo Yuqin , Wang Le , Xie Rong-Jun
Published: November 2023

Correction for ‘A super-high brightness and excellent colour quality laser-driven white light source enables miniaturized endoscopy’ by Shuxing Li et al., Mater. Horiz., 2023, 10, 4581–4588, https://doi.org/10.1039/D3MH01170D.
High spin polarization, large perpendicular magnetic anisotropy and room-temperature ferromagnetism by biaxial strain and carrier doping in Janus MnSeTe and MnSTe
Authors: Zhang Long , Zhao Yan , Liu Yuqi , Gao Guoying
Published: November 2023

Strain- and doping-dependent magnetic anisotropy energies and Curie temperatures of MnSeTe and MnSTe monolayers.
Suppressed Auger recombination and enhanced emission of InP/ZnSe/ZnS quantum dots through inner shell manipulation
Authors: Chen Yaru , Wang Rixin , Kuang Yanmin , Bian Yangyang , Chen Fei , Shen Huaibin , Chi Zhen , Ran Xia , Guo Lijun
Published: November 2023

The inner shell-regulated exciton dynamics, fluorescence blinking and photon emission properties of environmentally friendly InP/ZnSe/ZnS quantum dots.
The linkage-type and the exchange molecule affect the protein-labeling efficiency of iminoboronate probes
Authors: van der Zouwen Antonie J. , Jeucken Aike , van der Pol Elske , Boerema Gerben , Slotboom Dirk J. , Witte Martin D.
Published: November 2023

Acyl hydrazides are the most suitable substrates for the synthesis of iminoboronate probes. They have the appropriate balance between stability, which is required for targeting, and reversibility, which is required for detecting the labeled proteins.
QN-302 demonstrates opposing effects between i-motif and G-quadruplex DNA structures in the promoter of the S100P gene
Authors: Alexandrou Effrosyni , Guneri Dilek , Neidle Stephen , Waller Zoë A. E.
Published: November 2023

The potent G-quadruplex experimental drug QN-302 has strong opposing effects with i-motif DNA structures at the promoter of S100P.
Exploring effects of polymeric stabiliser molecular weight and concentration on emulsion production via stirred cell membrane emulsification
Authors: Manga Mohamed S. , Higgins Lucy , Kumar Akshai A. , Lobel Benjamin T. , York David W. , Cayre Olivier J.
Published: November 2023

Polymer stabiliser adsorption kinetics influence a stirred-cell membrane emulsification process output. An optimized combination of low/higher MW PVA at very low concentration (0.1 wt%) produces narrow size distribution and size-controlled droplets.
Selective dye adsorption by pH modulation on chemically modified nanopolyaniline by N-grafting of maleic acid
Authors: Rath Sai Sushree , Mohanty Nehapadma , Patra Braja N.
Published: November 2023

Polyaniline grafted maleic acid was synthesized via the ring opening reaction of maleic anhydride using polyaniline as a nucleophile. The polymer was used for selective removal of cationic (pH > 6.8) and anionic (pH < 6.8) dyes at different pH values.
Photoredox Ni-catalyzed decarboxylative arylation of oxamic acids for amide synthesis
Authors: Duan Depeng , Song Lu
Published: November 2023

Readily accessible oxamic acids are employed as carbamoyl radical precursors in photoredox nickel catalysis for amide synthesis.
Photoinduced defluorinative alkylation of trifluoromethyl alkenes with carbonyl derivatives by C–C bond scission
Authors: Yan Lu-Yu , Zhang Tian-Zhen , Lv Ze-Zhong , Fu Ming-Chen
Published: November 2023

A practical strategy for the photoinduced defluorinative alkylation of α-trifluoromethyl styrenes with carbonyl derivatives via C–C bond cleavage was disclosed.
Copper-catalyzed crosscoupling of vinyl nitrenes and CF3-carbenes to synthesize CF3-2-azadienes
Authors: Jiao Yongjuan , Wu Tao , Zhang Xinyu , Jiang Yaojia
Published: November 2023

A unique and efficient copper catalytic system has been established for the synthesis of fluorinated 2-azadienes from isoxazoles and CF3-N-tosylhydrazones via crosscoupling reactions of vinyl nitrenes with fluoroalkyl carbenes.
Enantioselective synthesis of pyrroloquinolines via a three-component Povarov reaction with aminoindoles
Authors: Zhou Zijie , Ye Ling , Yang Lu , Li Xinying , Zhao Zhigang , Li Xuefeng
Published: November 2023

This protocol provides concise access to enantioenriched pyrroloquinolines, and presents an alternative methodology for functionalizing the carbocyclic ring of indoles.
Kinetic study of rare earth elements extraction from decrepitated magnet powder using liquid magnesium
Authors: Stankovic Nicolas , Jourdan Julien , Marin Jérôme , Chagnes Alexandre , Quatravaux Thibault
Published: November 2023

Extraction of rare earth elements from spent NdFeB magnets with liquid magnesium was investigated using a laboratory scale perfect stirred reactor. Data were processed to model Nd extraction performances for treating decrepitated magnet powder.
One-pot four-component synthesis of novel isothiourea-ethylene-tethered-piperazine derivatives
Authors: Hajizadeh Fatima , Mojtahedi Mohammad M. , Abaee M. Saeed
Published: November 2023

A multicomponent synthesis of piperazines tethered to isothiourea group via an ethylene link was developed. Several derivatives of the target products are formed by combination of DABCO, alkyl bromides, secondary amines, and phenylisothiocyanate.
Recent advances in the utilization of covalent organic frameworks (COFs) as electrode materials for supercapacitors
Authors: Xu Shen , Wu Jinghang , Wang Xiang , Zhang Qichun
Published: November 2023

This review summarizes the recent advances in the electrode application of covalent organic frameworks (COFs) for supercapacitors, including the design strategies from the molecular scale to morphology control level and their device performance.
A highly efficient synthetic strategy for de novo NP encapsulation into metal–organic frameworks: enabling further modulated control of catalytic properties
Authors: Zhou Li , An Yuanyuan , Ma Jialong , Hao Guoxiu , Li Zhehui , Chen Junchen , Chou Lien-Yang
Published: November 2023

The surface-energy-dominated synthetic strategy to enhance efficiency of NP encapsulation into MOFs.
Hydrogen production by waste tire recycling by photo-pyrolysis
Authors: Silva Wanderson O. , Nagar Bhawna , Ellersiek Dennis , Bondaz Luc , Espín Jordi , Soutrenon Mathieu , Girault Hubert H.
Published: November 2023

Waste tires are a major environmental concern due to their non-degradable nature and the large area occupied by them in landfills worldwide.
Ice modulatory effect of the polysaccharide FucoPol in directional freezing
Authors: Guerreiro Bruno M. , Lou Leo T. , Rubinsky Boris , Freitas Filomena
Published: November 2023

Directionally grown sharp, anisotropic ice dendrites can be converted into thin, isotropic spicules or tubules (cooling rate-dependent) of enhanced symmetry and alignment with FucoPol, revealing its ice modulation effect.
Unraveling the role of surface and interfacial defects in hydrogen production to construct an all-in-one broken-gap photocatalyst
Authors: Li Jingwei , Wang Xuyu , Fang Hongli , Guo Xiaomin , Zhou Rongfu , Wang Cong , Li Jian , Ghazzal Mohamed Nawfal , Rui Zebao
Published: November 2023

A rational design of WO3−x/ZnFe2O4−x broken-gap heterojunction achieved higher charge carrier separation, light-harvesting ability, and good surface reaction, as an all-in-one photocatalyst for H2 generation.
A moisture-controlled Prussian white/CNT composite high energy cathode for next-generation sodium-ion batteries
Authors: Lee Jun , Jeong Wangchae , Baek Jaeryeol , Kim Yeongmin , Choi Yuri , Mathew Vinod , Sambandam Balaji , Alfaruqi Muhammad Hilmy , Kim Jaekook
Published: November 2023

In this study, we present a Prussian white–carbon nanotube (PW–CNT) composite material with a carbon conductive network as a promising high energy cathode for sodium-ion batteries (SIBs).
Dendronization of chitosan to afford unprecedent thermoresponsiveness and tunable microconfinement
Authors: Yao Yi , Shi Xiaoxin , Zhao Zihong , Zhang Afang , Li Wen
Published: November 2023

Dendronization of chitosan with 3-fold dendritic oligoethylene glycols generates stimuli-responsive and biocompatible dendronized chitosans, which form microconfinement to protect guests or modulate reactions. This confinement can be greatly enhanced through the formation of hydrogels.
A functionalized CNT-azobenzene-PVA-based self-healing aqueous gel as a conductive photo-responsive actuator
Authors: Narayanan Aswini , Bhagyasree T. M. , Torris Arun , Babu Sukumaran Santhosh
Published: November 2023

Responsive conductive gels have gained attention owing to potential applications in flexible displays, implantable medical devices, touch panels, wearable electronic skin, sensors, soft robotics, and related areas.
All-green Cs4CuSb2Cl12 perovskite films deposited in situ by AACVD and their doping with F− ions for photodetectors and memdiodes
Authors: Balderas-Aguilar Jesús Uriel , Falcony-Guajardo Ciro , Garduño-Wilches Ismael Arturo , Aguilar-Frutis Miguel Ángel , Hernández-Como Norberto , Martínez-Merlín Iván Enrique , García-Hipólito Manuel , Alonso-Huitrón Juan Carlos
Published: November 2023

Lead-free perovskite photoconductor devices fabricated by AACVD showcasing tunable morphological, photoresponse, memory window, electronic plasticity, and conductivity by F-doping.
Communication in Daily Life of Children With Developmental Language Disorder: Parents' and Teachers' Perspectives
Authors: Bruinsma Gerda Ingrid , Wijnen Frank , Gerrits Ellen
Published: November 2023

Purpose:

This study explores limitations in communication in daily life of children with developmental language disorder (DLD) from their parents' perspective as well as communicative abilities and social functioning in the classroom from their teacher's perspective. Furthermore, differences between children with mixed receptive–expressive disorder and children with expressive-only disorder in communication in daily life and social functioning are studied.

Method:

Data were collected through questionnaires completed by parents and teachers of children (5–6 years old) who attended schools for special education for DLD. Language test scores were retrieved from school records. Parents of 60 children answered open-ended questions about situations and circumstances in which their child was most troubled by language difficulties. Teachers of 83 children rated communicative abilities, social competence, and student–teacher relationship.

Results:

Parents reported communication with strangers as most troublesome and mentioned the influence of the mental state of their child. Parents considered limitations in expressing oneself and being understood and not being intelligible as core difficulties. Teachers rated the children's communicative abilities in the school context as inadequate, but their scores concerning social competence and the quality of teacher–child relationships fell within the normal range. Children with receptive–expressive disorder experienced limitations in communication in almost all situations, whereas those with expressive disorder faced limitations in specific situations. Children with receptive–expressive disorder were also significantly more limited in their communicative abilities and social competence at school than children with expressive disorder. No differences were found between the two groups in the quality of the teacher–child relationship.

Conclusions:

The results confirm that children with DLD face significant challenges in a variety of communicative situations. We found indications that children with receptive–expressive disorder experience more severe limitations than children with expressive disorder. The involvement of parents and teachers in evaluating a child's communicative ability provides valuable and clinically relevant information.
Increasing the resource efficiency of storing agricultural products
Authors: Novikova A.V. , Rudomazin V.V. , Sergienko O.I.
Published: November 2023

The article presents statistical data on the dynamics of the development of the Russian agro-industrial complex in the direction of increasing productivity and notes the problems faced by the processing industry (crop products). For successful crop production, plant protection products are used that enter the soil and groundwater, which indirectly affects the state of the environment. The importance of the implementation of the Long-term strategy for the development of the grain complex of the Russian Federation was emphasized. Analyzed data from studies on the storage of grain harvest, which is subjected to fumigation; an assessment of the safety of the tightness of the filled power carriers was carried out. The features of soil, water and air pollution in the zone of influence are discussed. The danger of using pesticides, which create risks of chemical contamination of environmental objects and food products of the population, is emphasized. Statistical information characterizing modern methods of grain storage in the Southern and Central Federal Districts, the pros and cons of these methods are considered. Examples of the practical significance of power runners in the process of grain storage are given (based on data from representatives of the agro-industrial complex). The issues of fumigation of the grain mass at the stage of storage in silobags are touched upon. The possibility of environmental impact of by-products of storage of grain mass is discussed. Ecological aspects of this storage technology are analyzed. Proposals for improving approaches to the storage of grain mass are formulated.
Biopharmaceutical study of general tonic capsules by in vitro method
Authors: Maksudova Feruza , Mamatkulov Zukhridin , Vakhidova Nargiza , Narzullaev Davronbek
Published: November 2023

One of the main indicators of the quality of modern drugs are biopharmaceutical indicators, in particular, the “Dissolution” test - for solid dosage forms, as well as theoretical and experimental justification for the creation of new drugs and improvement of existing ones, taking into account the increase in their therapeutic effect and the reduction of side effects on organism. The article presents the results of research on the development of the “Dissolution” test for Indian ginseng, conducted at the Tashkent Pharmaceutical Institute. Determination of the dissolution rate of drugs from solid dosage forms is carried out on the device “Rotating basket”. To study the release rate of active substances from the analyzed encapsulated dosage form, the generally accepted method “Rotating basket” included in the XIV edition of the State Pharmacopoeia (SP XIV) was used. Based on the results of the experiments, the following conditions for determining the bioavailability of the analyzed capsules by the in vitro method were selected: to determine the dissolution profile, two dissolution media are used in succession - a 0.1 M solution of hydrochloric acid (capsules should not dissolve within 60 minutes) and - a phosphate buffer solution with pH 7 ,4 (at least 75% of the active substances should be released within 45 minutes), the volume of the medium is 1000 ml, the rotation speed of the basket is 100 rpm, the temperature regime is 37±10oC.
Species composition of rare weeds in the south of the Far East
Authors: Morokhovets Tamara , Morokhovets Vadim , Skorik Nina , Vostrikova Svetlana , Markova Elena , Basai Zoya
Published: November 2023

The results of monitoring (2016–2022) of the weed component of agrophytocenoses in the Primorsky Territory of the Russian Federation are presented. The species affiliation of rare weeds was determined, the average occurrence of which in soybeans, early grain crops and corn was less than 5% and with a maximum average abundance of 0.53 pcs/m2. A total of 58 low active weed species were identified, 29 of which were not previously found in the surveyed areas. The data on the average frequency of occurrence of rare species, the density of infestation by them of all surveyed areas and the results of monitoring of crops of individual crops are analyzed. It has been established that the species diversity and abundance of rare weeds depend on the characteristics of cultivated crops. Weed species confined to individual crops and weeds growing everywhere have been identified. Eight species were recorded in areas under all crops: Galinsoga parviflora Cav., Potentilla anserina L., Gnaphalium uliginosum L., Arctium lappa L., Crepis tectorum L., Inula salicina L., Avena fatua L. and Poa pratensis L. Exclusively in 26 rare species were noted in soybean crops. In total, 57 low-active species were recorded in soybean agrocenoses, 26 species in corn crops, and 18 species in early grain crops. The most problematic species with increased occurrence in recent years, representing a potential danger for crop production in Primorsky Krai, have been identified.
Analysis of scientific research conducted to improve the efficiency of solar concentrator systems
Authors: Khuzhakulov S.M. , Faiziev T.A. , Sherkulov B.G. , Murodov I. , Samatova Sh.Y.
Published: November 2023

The article presents a scientific analysis based on scientific research conducted in the field of solar concentrators in leading institutions of the world. Parabolocylindrical concentrators with a free surface have been shown to be more efficient. concentrator model with free surface shape is proposed and based on its ability to solve problems in the design and analysis of optical systems, including boundary surfaces of arbitrary shape.
On the accepting state complexity of operations on permutation automata
Authors: Rauch Christian , Holzer Markus
Published: November 2023

We investigate the accepting state complexity of deterministic finite automata for regular languages obtained by applying one of the following operations on languages accepted by permutation automata: union, quotient, complement, difference, intersection, Kleene star, Kleene plus, and reversal. The paper thus joins the study of the accepting state complexity of regularity preserving language operations which was initiated in [J. Dassow, J. Autom., Lang. Comb. 21 (2016) 55–67]. We show that for almost all of the above-mentioned operations, except for reversal and quotient, there is no difference in the accepting state complexity for permutation automata compared to deterministic finite automata in general. For both reversal and quotient we prove that certain accepting state complexities cannot be obtained; these numbers are called “magic” in the literature. Moreover, we solve the left open accepting state complexity problem for the intersection of unary languages accepted by permutation automata and deterministic finite automata in general.
Posterior Sinuplasty: A New Strategy for Managing Hydrocolpos in Cloaca—Case Series
Authors: AbouZeid Amr AbdelHamid , Abdelmoniem Ahmed Saad , Fathy Mohamed Abdelrahman , Negm Mohamed Ahmed , Mohammad Shaimaa Abdelsattar
Published: November 2023

We present a simple surgical technique aiming to improve urine outflow through the common urogenital sinus in cloaca and facilitate drainage of existing hydrocolpos. The study included three cases of cloaca with associated hydrocolpos that were operated during the period 2022 through 2023. The patient is placed in the prone position for a standard posterior sagittal anorectoplasty. The distal rectal fistula is severed flush with the vagina/sinus leaving an open defect in the posterior wall of the vagina/sinus. The defect is then widened distally via a vertical incision (∼1 cm) through the posterior wall of the common urogenital sinus toward but not reaching the perineum. This vertical defect is then closed horizontally displacing the posterior vaginal wall downwards toward the perineum (posterior sinuplasty). The postoperative recovery was uneventful in the three cases. Adequate drainage of hydrocolpos was confirmed by imaging at follow-up, as well as improvement of upper urinary tract dilatation. In selected cases of cloaca, posterior sinuplasty is a simple procedure that can be applied during anorectoplasty to provide effective drainage of associated hydrocolpos.
Bidentate Lewis Acid-Catalyzed Inverse Electron-Demand Diels–Alder Reaction of Phthalazines and Cyclooctynes
Authors: Wegner Hermann A. , Große Michel
Published: November 2023

Herein we report a method for facilitating the inverse-electron-demand Diels–Alder reaction of 1,2-diazines and cyclooctynes by utilizing a boron-based bidentate Lewis acid catalyst. Readily available electron-deficient and electron-rich phthalazines proved to be suitable substrates in this transformation. The described method enables the facile construction of diversely substituted polycyclic aromatic hydrocarbons fused to eight-membered carbocycles.
Simulation-Based Bypass Training and Learning Curves—Resident Experience
Authors: Jalolova Mohira , Jankovic Dragan , Sasaki Kento , Tanaka Riki , Kato Yoko
Published: November 2023

Introduction Bypass surgery is a challenging operative procedure that requires surgical excellence. Achieving the skills required for vascular surgery is difficult to master in the operating room without intensive microsurgical training. Various models have been developed to provide training to young neurosurgeons and increase dexterity and patient safety. Bypass surgery requires complex microsurgical techniques.

Methods Microanastomosis training was performed on plastic tubes and chicken wings for 2 months. Each microanastomosis was evaluated by a senior author.

Results An improvement in the quality and patency of microanastomosis was observed.

Conclusion Microsurgical simulation training can contribute to the improvement of surgical skills and dexterity.
OCT angiography in the monitoring of vaginal health
Authors: Qiu Saijun , Arthur Afiba , Jiang Yuchen , Miao Yusi , Li Yan , Wang Jingyi , Tadir Yona , Lane Felicia , Chen Zhongping
Published: November 2023

Fractional-pixel CO2 laser therapy shows promise for treating the genitourinary syndrome of menopause (GSM). Nevertheless, it remains controversial in the field of female pelvic medicine. This is due to the inherent difficulties in obtaining noninvasive biopsies to evaluate the treatment's efficacy and safety objectively. To address this challenge, we developed a noninvasive intravaginal optical coherence tomography (OCT)/OCT angiography (OCTA) endoscopic system, whose probe features a shape identical to the laser treatment probe. This system can provide high-resolution OCT images to identify the microstructure of vaginal tissue and visualize the vasculature network in vivo. We conducted clinical research on 25 post-menopausal patients with GSM. OCT/OCTA scans were acquired at four different locations of the vagina (distal anterior, distal posterior, proximal anterior, and proximal posterior) during the whole laser treatment session. A U-Net deep learning model was applied to segment the vaginal epithelium for assessing vaginal epithelial thickness (VET). Blood vessel density and VET were quantified to monitor the efficacy of fractional-pixel CO2 laser therapy. Statistical correlation analyses between these metrics and other clinical scores were conducted, validating the utility of our system. This OCT/OCTA endoscopic system has great potential to serve as a noninvasive biopsy tool in gynecological studies to screen, evaluate, and guide laser treatment for GSM.
Influence of incoming turbulence and shear on the flow field and performance of a lab-scale roof-mounted vertical axis wind turbine
Authors: Jooss Y. , Hearst R. J. , Bracchi T.
Published: November 2023

Flow conditions in an urban environment are complex, featuring varying levels of turbulence intensity and shear. The influence of these flow characteristics on the performance of a roof-mounted vertical axis wind turbine of the Savonius (drag) type is investigated at lab scale. Five different inflow conditions are generated with an active grid in a wind tunnel, covering turbulence intensities from 0.9% to 11.5% and relative vertical shear from 0% to 17%. The flow field is captured using particle image velocimetry, and the power output of the turbine is assessed through measurements of the converted power. The set-up consists of two-surface mounted cubes aligned with each other in the main flow direction, spaced apart by two cube heights. The turbine is placed on top of these model buildings at six different streamwise positions along the centerline and at two different heights. It was observed that the turbulence intensity in the inflow has a significant impact on the flow field and also on the power output of the turbine. The increasing turbulence intensity leads to smaller regions of recirculating flow. Thus, the turbine experiences higher flow velocities, which is reflected in the measured power. The influence of shear is comparably small on both the flow field and the turbine performance. The higher of the two turbine positions yields higher power output overall. Furthermore, it was shown that the impact of the turbine on the flow field is significant for all inflow conditions and can vary substantially depending on the inflow.
Research on the action characteristics and breaking control of 100 kA series double break DC vacuum circuit breaker for CRAFT quench protection system
Authors: Hu Xingguang , Li Hang , Li Hua , Song Zhiquan , Gao Xiang , Li Jiangang
Published: November 2023

The DC vacuum circuit breaker plays an important role in the quench protection system of the Comprehensive Research Facility for Fusion Technology (CRAFT) project. The study of the operating characteristics of vacuum circuit breakers can effectively improve breaking reliability. This article introduces the design and basis of the series double break DC vacuum circuit breaker for the CRAFT quench protection system. It adopts the electromagnetic repulsion driving method to ensure rapid action and the operating mechanism design to ensure the synchronization of the double break action. A magnetic shielding setting is proposed through simulation calculations to solve the uniformity of magnetic induction strength between breaks. Combining the test data of action characteristics with the theory of optimal opening distance for current zero crossing, a DC breaking platform for the vacuum circuit breaker was designed, and control strategies were determined, thus completing the 100 kA DC breaking experiment. The vacuum circuit breaker studied in this article meets the technical requirements of the CRAFT quench protection system and provides experience and experimental data for the design of high-current vacuum circuit breakers.
INDETERMINATE1
-mediated expression of
FT
family genes is required for proper timing of flowering in
Brachypodium distachyon
Authors: Liu Bing , Woods Daniel P. , Li Weiya , Amasino Richard M.
Published: November 2023

The transition to flowering is a major developmental switch in plants. In many temperate grasses, perception of indicators of seasonal change, such as changing day-length and temperature, leads to expression of
FLOWERING LOCUS T1
(
FT1
) and
FT-Like
(
FTL
) genes that are essential for promoting the transition to flowering. However, little is known about the upstream regulators of
FT1
and
FTL
genes in temperate grasses. Here, we characterize the monocot-specific gene
INDETERMINATE1
(
BdID1
) in
Brachypodium distachyon
and demonstrate that
BdID1
is a regulator of
FT
family genes. Mutations in
ID1
impact the ability of the short-day (SD) vernalization, cold vernalization, and long-day (LD) photoperiod pathways to induce certain
FTL
genes.
BdID1
is required for upregulation of
FTL9
(
FT-LIKE9
) expression by the SD vernalization pathway, and overexpression of
FTL9
in an
id1
background can partially restore the delayed flowering phenotype of
id1
. We show that BdID1 binds in vitro to the promoter region of
FTL
genes suggesting that ID1 directly activates
FTL
expression. Transcriptome analysis shows that
BdID1
is required for
FT1
,
FT2
,
FTL12
, and
FTL13
expression under inductive LD photoperiods, indicating that
BdID1
is a regulator of the
FT
gene family. Moreover, overexpression of
FT1
in the
id1
background results in rapid flowering similar to overexpressing
FT1
in the wild type, demonstrating that
BdID1
is upstream of
FT
family genes. Interestingly,
ID1
negatively regulates a previously uncharacterized
FTL
gene,
FTL4,
and we show that
FTL4
is a repressor of flowering. Thus,
BdID1
is critical for proper timing of flowering in temperate grasses.
Rights-based approaches and Indigenous peoples and local communities: Findings from a literature review
Authors: Sarmiento Barletti Juan Pablo , Prouchet Léna , Larson Anne M.
Published: November 2023

This preliminary assessment of rights-based approaches (RBAs) seeks to contribute to the ongoing discussions of RBAs for Indigenous Peoples and local communities (IPs and LCs). RBAs purposefully position the recognition of, respect for, and access to individual and collective rights as central to an initiative’s planning, design, implementation, process monitoring, and outcomes. In mainstream climate change, conservation, and development programs and policies, this means refocusing the relationship between “beneficiaries” and “implementers” to one of rights-holders and duty-bearers. RBAs hold growing discursive importance in relation to the rights of IPs and LCs in conservation and climate change spheres, including the agendas of international agencies. The growing interest in RBAs, and their inclusion in frameworks that will guide development, conservation, and climate projects over the next decade, is laudable. However, there are few reviews that seek to understand how RBAs emerged and how they have been conceptualized. Such analysis is a necessary basis from which to advance discussions on the impact of RBAs and provide lessons to support them. In this review, our primary interest is the conception, conceptualization, and implementation of RBAs in forest-based initiatives, but we reviewed the wider scholarly and gray literature on RBAs in development, conservation, and climate action initiatives.
Methods and models for fibre–matrix interface characterisation in fibre-reinforced polymers: a review
Authors: AhmadvashAghbash Sina , Verpoest Ignaas , Swolfs Yentl , Mehdikhani Mahoor
Published: November 2023

The fibre–matrix interface represents a vital element in the development and characterisation of fibre-reinforced polymers (FRPs). Extensive ranges of interfacial properties exist for different composite systems, measured with various interface characterisation techniques. However, the discrepancies in interfacial properties of similar fibre–matrix systems have not been fully addressed or explained. In this review, first, the interface-forming mechanisms of FRPs are established. Following a discourse on three primary factors that affect the fibre–matrix interface, the four main interface characterisation methods (single-fibre fragmentation, single-fibre pull-out, microbond and fibre push-in/-out tests) are described and critically reviewed. These sections review various detailed data reduction schemes, numerical approaches, accompanying challenges and sources of reported scatter. Finally, following the assessment of several infrequent test methods, comprehensive conclusions, prospective directions and intriguing extensions to the field are provided.