bluuebunny/crossref_metadata_2025 huggingface dataset:
Immersing in problems: Challenges of women living with the husband on hemodialysis
Authors: Baghcheghi Nayereh , Ashktorab Tahereh , Seyedfatemi Naiemeh
Published: December 2019

Background & Aim: The caregivers of hemodialysis patients experience a heavy caregiving burden. More caregiving pressure and burden have been reported of the women than men insofar as they are encountered with more physical and psychological problems. This paper explores the challenges faced by women living with husband on hemodialysis. Methods & Materials: The study followed a conventional content analysis method. The participants were selected through a purposive sampling method in hospitals of Shahid Beheshti University of Medical Sciences, Tehran, Iran, in 2017-2018. The first author performed semi-structured, individualized interviews with 14 participants. Results: By analyzing the data, the main category "Immersing in problems" was extracted with two following categories: 1- Inadequate support network (subcategories: inadequate informational support, inadequate instrumental support, inadequate emotional support) and 2- Difficult coexistence with problems (subcategories: role overload, worry and anxiety, fear and hope for the future, suffering of frequent dialyses). Conclusion: The findings of the study showed that women living with the husband on hemodialysis have been encountered with challenges and numerous stressing factors in the course of caregiving. Given the challenges experienced by participants, telenursing, and community health nurses can play an essential role in eliminating the many problems of hemodialysis patients and their caregivers.
The effect of vaginal evening primrose on the Bishop score of term nulliparous women
Authors: Najafi1 Motahareh , Loripoor Marzeyeh , Saghafi Zahra , Kazemi Majid
Published: December 2019

Background & Aim: Desirable bishop score is necessary for having a successful delivery. Prostaglandins are effective on cervical ripening, and primrose contains precursors of these materials. Therefore, the present study was conducted to evaluate the effect of vaginal Evening primrose on the bishop score among term nulliparous women. Methods & Materials: The present double-blind, randomized clinical trial was conducted on 86 nulliparous women who referred to the comprehensive health service centers of Rafsanjan from November 2017 to May 2018. The samples were selected through convenient sampling method and allocated into two intervention and placebo groups with simple random assignment. The intervention group used a daily dose of 1000 mg vaginal capsules of Evening primrose from the 38th week of pregnancy until delivery, and the placebo group received a similar placebo with a similar administration method. The Information about the women’s bishop score was gathered from the participants’ medical files in the hospital and then was analyzed using SPSS software version 16 and Kolmogorov-Smirnov test, Chi-square test, and independent t-test. Results: The total mean and standard deviation of the bishop score in the intervention and placebo groups were respectively 7.83 ± 2.09 and 4.46 ± 2.39, and the simplified bishop score in the intervention and the control groups was respectively 5.93 ± 2.42 and 2.81 ± 2.02. The difference between the two groups considering both of the bishop scores was statistically significant (p = 0.001). Conclusion: Vaginal Evening primrose is useful to ripen the cervix of term nulliparous women, and so, it could be administered for this purpose.
Sexual counseling to patients with myocardial infarction: Nurses' performance, responsibility and confidence
Authors: Gazestani Tayyebeh , Mangolian Shahrbabaki Parvin , Mehdipour Rabori Roghayeh , Azzizadeh Forouzi Mansooreh
Published: December 2019

Background & Aim: One of the main concerns in patients with myocardial infarction is that there is no return to sexual activities. Sexual counseling is an interaction between patient and nurse that requires appropriate performance, responsibility, and confidence. The present study aimed to determine nurses' performance, responsibility, and confidence in sexual counseling of myocardial infarction patients. Methods & Materials: This descriptive/analytical cross-sectional study was carried out on 180 nurses from the cardiac care unit (CCU) at the hospitals located in southeastern Iran in 2018. Sampling was performed with the census method; and the data collection tool was a demographic information form and questionnaire, involving nurses' performance, responsibility, and confidence in sexual counseling of cardiac patients. Information was analyzed using SPSS software (ver.18) through descriptive and inferential statistics, including t-test, ANOVA, and Pearson correlation coefficient. The significance level was considered as 0.05. Results: The mean of total performance scores in the nurses was 14.54 ± 4.4, indicating the average performance of nurses in the sexual counseling of myocardial infarction patients. The total mean score of responsibility was 14.32±2.7, indicating their average responsibility in sexual consultation. The total mean score of confidence was 12.86±2.35, indicating their average confidence in the sexual counseling of cardiac patients. Conclusion: The present research showed that nurses’ performance and confidence were not high or acceptable in the sexual counseling of patients with a myocardial infarction, which can lead to some dangerous events such as recurrent myocardial infarction or sudden death. Thus, holding some workshops or training related to the sexual counseling of the patients can assist nurses to be better in this case.
THE ATTITUDE OF UNIVERSITY STUDENTS TOWARDS CELEBRITY ENDORSEMENTS THROUGH SOCIAL MEDIA
Authors: Alshetti Ahmed , Al Mubarak Muneer
Published: December 2019

Purpose of the study: The study aims to identify the factors that influence students’ attitudes when celebrity endorsements are used through social media. It seeks to determine how effective endorsements are from the consumers’ point of view.

Methodology: A study model was developed to show the effect of different factors on students’ attitudes. A quantitative approach was used for data collection to support the model. This study employed a survey method using a questionnaire to gather information from participants.

Main findings: The findings show celebrity characteristics and social media advertisements affect students’ attitudes. The results were positive for students’ attitude towards celebrity endorsements through social media.

Applications of the study: The study provides insights into how businesses should plan marketing campaigns and influence students’ attitudes towards celebrity endorsements through social media. Companies are encouraged to use social networks to track and respond to the opinions of their customers in a timely manner.

Novelty/Originality of this study: There is a shortage of literature that is associated with celebrity endorsements through social media. This study aims to fill in the gap in knowledge and practice by identifying business opportunities and optimizing available marketing tools that can be used in order to gain a better image.
The Synthesis of New Phosphazene-Bearing Ethyl p-Hydroxybenzoate and Ferrocenyl Pendant Groups and their Spectroscopic and Crystallographic Characterizations
Authors: TÜMER Yasemin , ÇAYIRBAŞI Mahmut , ŞAHİN Onur , HÖKELEK Tuncer
Published: December 2019

Herein, we
report a study of novel hexachlorocyclotriphosphazene (N3P3Cl6)
derivatives bearing ethyl p-hydroxy benzoate
and pendant ferrocenyl groups. Characterizations of the products [mono- 2, di- (geminal 3a; non-geminal transa-3b, transb-3c and cis-3d), tri- 4 and tetra-
5
substitue phosphazene derivatives] were performed using elemental analysis and spectral methods. The structure
of the two compounds  (2 and 5) are
elucidated by X-ray diffraction techniques.
Manifestations of deep degasing into the water column and upper part of the Pechora sea sedimentary section
Authors: Sokolov Sergey Yu. , Moroz Evgeniy A. , Sukhikh Elena A. , Razumovskiy Anatoliy A. , Levchenko Oleg V.
Published: December 2019

Studies of acoustic anomalies in the water column and seismoacoustic anomalies in the Quaternary sediments of Pechora sea and their relationship with deep hydrocarbon sources were conducted by the Institute of Oceanology of the Russian Academy of Sciences and the Geological Institute of the Russian Academy of Sciences in the 38th cruise of RV “Academik Nikolaj Strakhov” in 2018. Mapping of free gas manifestations presents an additional indicator of tectonic activity and the fault network frame, which provides the flow of fluids from deep horizons. Comparison of high-resolution seismic survey data with deep seismic survey data shows that the fluid in the upper part of the section is first accumulated under the bottom of Jurassic-Cretaceous sedimentary sequences, which are fluid-resistant. Local dislocations of fluid trap lead to further rise and redistribution of free gas in Quaternary sequences. Natural or artificial break of their integrity results in the release of gas into the water column from near-surface accumulations that were found in the form of “bright spot” anomalies on seismic-acoustic records. Mapping of sound scattering objects in the water column shows the degassing areas, which are usually located above the deep faults. “Bright spots” of free gas in the Quaternary sequences have a variety of shapes – multi-tiered and inclined. Gas breaks into the water column occur near the edges of these anomalies. Systematic mapping of the considered phenomena is a necessary element in the preparation of the area for industrial operation.
Hydrodynamic features of oil and gas bearing deposits of the southern areas of Ob-Irtysh interfluves
Authors: Novikov Dmitry A. , Dultsev Fedor F. , Chernykh Anatoliy V. , Ryzhkova Svetlana V.
Published: December 2019

The results of study of hydrogeological conditions of oil and gas bearing deposit of the southern areas of Ob-Irtysh interfluves (southern regions of West Siberian basin) are presented. The hydrodynamic field is characterized by direct dependence and the presence of normal and increased pressure (formation anomalous pressure factor not exceed 1.13) is common in Apt-Alb-Cenomanian, Neokomian, Jurassic and pre-Jurassic complexes. The results of study of the reservoir properties and hydrodynamic conditions indicated that the elision water exchange play the dominant role in the modern hydrogeological structure formation. Two types of water drive system is established: elisional (lithostatical and termodehydrational) in the inner areas (southern part of Koltogor-Nyurolsky trench, Nyurolskaya megadepression, Verkhnevasyugansk anteclise and other structures) and infiltrational within the territory of Baraba-Pikhtovo monocline. Elisional system is replaced by the elisional-termodehydrational at the depth 2.0-2.2 km. Large piezo maximum zones (southern part of Koltogor-Nyurolsky trench and Nyurolskaya megadepression) become the inner regions of water pressure generation (the inner feed areas) with the maximal degree of hydrogeological closure of the interior. The region of piezo minima, tracing the structures of the Barabinsk-Pikhtovskaya megamonocline, relates to the external feed area. The hydrodynamic model of the southern areas of Ob-Irtysh interfluves is building for the first time and allow to predict the pressure change trends in the areas with poorly provided with the actual data.
LAS FUMIGACIONES CON GLIFOSATO (“ROUND UP”) A LOS CULTIVOS DE DROGAS EN TERRITORIOS INDÍGENAS EN COLOMBIA
Authors: Arenas-Mendoza Hugo Andrés
Published: December 2019

Este artículo tiene por objetivo demostrar que el marco normativo colombiano de la lucha contra el narcotráfico con fumigaciones aéreas con glifosato ha desconocido gravemente los derechos de los pueblos indígenas, por lo que la Corte Constitucional ha tenido que tutelarlos. La metodología aplicada parte de un análisis histórico general de las principales normas sobre glifosato, con el fin de exponer su evolución y posteriormente, se realiza un estudio jurisprudencial que expone la manera en que la Corte Constitucional ha reconducido la interpretación normativa sobre el glifosato. De este modo, se han obtenido los resultados siguientes: 1. Los lineamientos jurídicos en materia de fumigaciones áreas con glifosato vulneran los derechos de los indígenas y 2. La Corte Constitucional ha tutelado derechos fundamentales de los indígenas como la libre determinación de los pueblos, la consulta previa, la diversidad étnica y cultural, la participación, la salud en conexión con la vida y al medio ambiente. En conclusión, se puede ver como la Corte Constitucional al no estar de acuerdo con los lineamientos sobre glifosato, ha modificado su contenido generando nuevas políticas públicas que desembocaron en la prohibición de las fumigaciones con este químico y colocaron un riguroso procedimiento para su futura autorización.
El derecho humano a un medio ambiente sano, la participación pública y el ius commune
Authors: Aguilar Cavallo Gonzalo Javier
Published: December 2019

El derecho humano a disfrutar de un medio ambiente sano, o bien, sin riesgos, limpio, saludable y sostenible se encuentra vinculado con el derecho de acceso a la participación ambiental. La participación pública es un medio para alcanzar el derecho a un medio ambiente sano, pero también forma parte de su contenido. La jurisprudencia de la Corte Interamericana de Derechos Humanos ha desarrollado el derecho a la participación ambiental. De este modo, la Corte ha contribuido a establecer estándares mínimos que forman parte del ius commune de derechos humanos en América Latina. El objetivo principal de este trabajo es determinar la relevancia y el rol que juega la participación pública en la protección ambiental, así como las normas que lo apuntalan. En este contexto, la pregunta que orientaría el estudio sería ¿cuál es el rol que juega la participación pública en la protección ambiental y cuáles son las fuentes de la misma? El método utilizado será el del análisis dogmático y normativo, junto con la técnica de revisión documental.Encontramos que la satisfacción plena de los derechos de consulta, participación y consentimiento en el ámbito ambiental, son supuestos necesarios para la realización de una democracia real, participativa y deliberativa. Desde el derecho internacional de los derechos humanos comienzan a desarrollarse estándares participatorios ambientales mínimos que se proyectan como comunes para los Estados.
APRESENTAÇÃO
Authors: Rezende Elcio Nacur
Published: December 2019

Apresentação da Veredas do Direito – Direito Ambiental e Desenvolvimento Sustentável, v. 16, n. 36, set./dez. 2019.
Eficiencia competitiva de los cantones en Costa Rica: Análisis del índice de competitividad cantonal basado en modelos frontera no-paramétricos
Authors: Araya Solano Manuel
Published: December 2019

Este estudio emplea un modelo de Análisis Envolvente de Datos (DEA) con un único input constante para analizar la eficiencia competitiva de los cantones costarricenses para el año 2016. Los resultados de eficiencia, como frutos del análisis de las siete dimensiones (pilares) del Índice de Competitividad Cantonal (ICC) como outputs de la función de producción no-paramétrica propuesta en este trabajo, indican que, en promedio, los cantones costarricenses pueden mejorar su eficiencia competitiva un 56,84%. Además, los resultados sugieren que la configuración de pilares competitivos tiene importantes implicaciones para la evaluación de eficiencia. En provincias relativamente más desarrolladas, que presentan aglomeraciones urbanas, los pilares competitivos relacionados con las infraestructuras, el empleo, la calidad de vida y la innovación, son las principales prioridades en el diseño de políticas de apoyo que explican el resultado de la eficiencia competitiva; mientras que los indicadores de empleo y calidad de vida son los principales pilares que explican la eficiencia competitiva en las provincias menos desarrolladas. El ICC es un instrumento valioso para monitorear el desempeño competitivo de los cantones, mientras que el enfoque analítico propuesto basado en un modelo DEA puede ofrecer información útil a los observadores de políticas de apoyo que permita identificar qué acciones estratégicas pueden ayudar a optimizar las políticas de asignación de recursos y, como resultado, la competitividad de los cantones.
On the Local Adjacency Metric Dimension of Generalized Petersen Graphs
Authors: Marsidi Marsidi , Dafik Dafik , Agustin Ika Hesti , Alfarisi Ridho
Published: December 2019

The local adjacency metric dimension is one of graph topic. Suppose there are three neighboring vertex , ,  in path . Path  is called local if  where each has representation: a is not equals  and  may equals to . Let’s say, .  For an order set of vertices , the adjacency representation of  with respect to  is the ordered -tuple , where  represents the adjacency distance . The distance  defined by 0 if , 1 if  adjacent with , and 2 if  does not adjacent with . The set  is a local adjacency resolving set of  if for every two distinct vertices ,  and  adjacent with y then . A minimum local adjacency resolving set in  is called local adjacency metric basis. The cardinality of vertices in the basis is a local adjacency metric dimension of , denoted by . Next, we investigate the local adjacency metric dimension of generalized petersen graph.
Pedagogia do esporte
Authors: Costa Roberto Rocha , Santos Marcele Oliveira Pil dos , Pereira Shanaine de Souza , Galatti Larissa Rafaela , Scaglia Alcides José
Published: December 2019

Objetivo: Identificar o quanto e como aparece o termo Pedagogia do Esporte em periódicos científicos da Educação Física no Brasil. Além de indicar quais periódicos científicos nacionais têm publicações sobre Pedagogia do Esporte, pretendeu verificar as variações na quantidade de publicações ao longo desses seis anos, quais os autores que publicaram sobre o tema, e finalmente apresentar que temas ou assuntos foram abordados. Métodos: A pesquisa foi descritiva e com coleta de dados online dos periódicos nacionais, de janeiro de 2010 até junho de 2015. Como critério para a seleção dos artigos, o termo Pedagogia do Esporte deveria aparecer nas palavras-chave e/ou no título dos estudos. Resultados: Foram analisados quarenta (40) artigos publicados nos seis anos, com uma frequência de 7,3 artigos por ano, somente três (3) autores se destacaram com oito (8) ou mais artigos publicados, sendo metodologias de ensino, o assunto mais abordado. Conclusão: Concluímos que as publicações com o termo Pedagogia do Esporte seguem em estágio de desenvolvimento, que há ainda áreas a serem mais estudadas e que os autores devam usar o termo em seus títulos e/ou palavras-chave para facilitar a busca por pesquisas dessa disciplina.
Avaliação em saúde antes da prática de exercícios físicos
Authors: Rosa Claudio Damião , Profice Christiana Cabicieri
Published: December 2019

Introdução: A prática regular de exercício físico (EF) é compreendida como principal meio não medicamentoso de prevenir doenças e melhorar a qualidade de vida. A avaliação antes do início da prática de exercícios (pré-participação) é fundamental para a prática segura e eficiente. Objetivos: Este estudo tem como objetivo abordar a relevância da avaliação em saúde, seus principais protocolos e as atualizações do American College of Sports Medicine (ACSM). Metodologia: O termo “preparticipation health screening” foi utilizado na base de dados PubMed e Google Scholar. Resultados e Discussão: De acordo com a literatura, informações obtidas por meio da avaliação pré-participação facilitam a escolha do exercício mais adequado e seguro. Os principais protocolos de avaliação pré-participação em saúde se baseiam, em geral, na presença de sintomas de doenças cardiovasculares, metabólicas e renais. As novas orientações do ACSM indicam que na avaliação pré-participação é mais adequado considerar a presença de sinais ou sintomas de doenças cardiovasculares (DCV), metabólicas ou renais, o condicionamento físico atual do indivíduo e a intensidade do exercício desejada. Conclusão: Considerando as novas orientações do ACSM, é possível diminuir as barreiras para o início de um programa de EF e ainda assim garantir a segurança de seus praticantes.
Atividade física como estratégia no processo de reabilitação psicossocial de dependentes químicos
Authors: Honorato Eduardo Jorge Sant'Ana , Anselmo Suzane Monteiro Gonçalves , Lemos Sonia Maria , Ferreira Darlisom Sousa , Silva Tirza Almeida da
Published: December 2019

Objetivo: Identificar quais benefícios que a atividade física pode oferecer como estratégia no processo de reabilitação psicossocial de um dependente químico e os efeitos produzidos por ela sobre o indivíduo. Metodologia: revisão sistemática integrativa, tendo como base de dados os artigos encontrados no google acadêmico no período de 2006 a 2015. Resultados e discussão: Estudos demonstram que a prática de atividade física regular traz diversos benefícios, não somente para saúde física, mas principalmente para saúde mental. Sabemos também que o número de dependentes químicos cresce alarmantemente em nossa sociedade e já é considerado um quadro epidêmico. Pode-se destacar os efeitos da atividade física como estratégia no processo de reabilitação de dependentes químicos e identificar como a prática de atividade física está sendo discutida como fator protetivo no processo de reabilitação. Conclusão: Enseja-se por meio desta análise, que os resultados possam direcionar a aplicação da atividade física de forma mais efetiva no tratamento de dependentes químicos. Conclui-se que os artigos apontam para a importância significativa no tratamento, uma vez que esta possibilita a melhora das condições de saúde e de qualidade de vida, entre outros.
Hóquei sobre a Grama e Indoor no estado do Rio Grande do Sul
Authors: Finco Daniel David , Finco Mateus David , Mazo Janice Zarpellon
Published: December 2019

Objetivo: Descrever como ocorreu a trajetória da modalidade hóquei sobre a grama e indoor com base nas ações realizadas no primeiro mandato da Federação de Hóquei sobre a Grama e Indoor do Estado do Rio Grande do Sul (FHERS) de 2010 a 2014. Métodos: Esta pesquisa histórico-documental foi elaborada por meio de revisão bibliográfica, pela análise de documentos e de fontes orais com seis entrevistas com fundadores e dirigentes do primeiro e segundo mandatos da FHERS. Resultados: A trajetória da modalidade está vinculada a clubes, escolas, projetos sociais e universidades. Estas instituições foram o alicerce para o desenvolvimento de cursos, oficinas, workshops, vivências, práticas em aulas de educação física e em projetos de extensão, a criação da disciplina eletiva da modalidade na Universidade Federal do Rio Grande do Sul e a realização de festivais e campeonatos da modalidade. Conclusão: Em razão de o Brasil sediar os Jogos Pan-Americanos e os Jogos Olímpicos, a implantação desse esporte no território sul-rio-grandense, ocorreu através de recursos financeiros tanto da esfera nacional quanto estadual, além da visibilidade dada ao esporte devido a esses megaeventos.
Entre a racionalidade médica e o espetáculo do circo
Authors: Guerra Laryssa Rangel , Menez Yuri Santos de , Santos Felipe Lameu dos
Published: December 2019

Introdução: A historiografia da Educação Física apontou que o saber médico era um dos mais importantes para a legitimação da ginástica no Brasil do século XIX. Objetivo: Compreender as propostas de ginásticas defendidas nos periódicos médicos no Rio de Janeiro entre os anos de 1870 e 1879. Métodos: Os documentos tornados fontes do conhecimento histórico foram os artigos publicados nos Annaes Brasilienses de Medicina, no Progresso Médico e na Revista Médica que abordava uma temática da educação física e/ou ginástica dentro do período pesquisado. Resultados: A partir das fontes, percebe-se a relação estabelecida entre a ginástica e um modelo de educação integral que abarcava a educação intelectual, moral e física. A ginástica seria uma das formas de se alcançar a educação física do modelo de educação integral, mas não só isso, ela também tinha um forte componente moral e uma ligação com a busca da criação de um espírito nacionalista. A ginástica, defendida pelos artigos analisados, era criada em contraposição a ginástica praticada nos circos, que ao olhar dos médicos era entendida como não higiênica e como contra-norma. Eram estabelecidos conflitos entre o saber médico e o saber circense sobre a ginástica. Conclusão: As fontes dão indícios de que o saber médico disputava espaço com outras formas de conceber os exercícios ginásticos.
Organização didático-pedagógica das aulas de educação física na educação básica
Authors: Maldonado Daniel Teixeira , Jabois Diego Pinto , Neira Marcos Garcia
Published: December 2019

Relatam-se duas experiências com a tematização dos esportes. A primeira trata de um projeto educativo realizado em uma escola municipal de Itanhaém, com o desenvolvimento de esportes com bastão e/ou implementos, para estudantes dos anos finais do Ensino Fundamental. A segunda experiência educativa ocorreu no Ensino Médio, em uma escola da rede federal de ensino, com vivências de esportes coletivos, individuais, radicais e para pessoas com deficiência, além de refletir sobre questões biológicas, fisiológicas, históricas, sociais, econômicas e políticas relacionadas às práticas esportivas. Após as reflexões expostas nesse texto, é possível concluir que entramos em um paradigma em que os professores e as professoras são intelectuais no tratamento da sua própria prática pedagógica.
Lipofobia, disciplinamento do corpo e produção de valor
Authors: Freitas Rogério Gonçalves de , Pereira Lana Lima , Alves Pamela Soares , Oliveira Marcos Renan Freitas de
Published: December 2019

Objetivo: Este artigo versa sobre a relação existente entre lipofobia, disciplinamento do corpo e produção de valor. Procurou entender a lipofobia como técnica biopolítica de disciplinamento do corpo. Método: O caráter metodológico deste artigo foi qualitativo e bibliográfico. Resultados e Discussão: Percebemos que a subjetivação lipofóbica contribui para o desejo de um estilo de vida saudável para a produtividade no trabalho e o consumo de um corpo-capital. Conclusão: Concluímos que o modelo de governamentalidade neoliberal utiliza-se da lipofobia como política social para o disciplinamento do corpo, no qual o corpo-capital torna-se espaço de dominação e o consumo ganha uma dimensão mais complexa, já que o “bem” comprado adere-se ao corpo criando novas cadeias de produção de valor para o capital.
Osteogenesis imperfecta and cerebrospinal fluid leak: a unique presentation and treatment challenge
Authors: Pompeu Clara Mota Randal , Matos Anna Caroline Rodrigues de Souza , Pompeu Mirian Mota Randal , Meireles Luis Fernando Falcão de Castro , Dias Daniel Aguiar , Gomes Erika Ferreira
Published: December 2019

Introduction: Osteogenesis imperfecta (OI) is a heritable disorder of the connective tissue that mainly manifests as bone fragility. Other signs and symptoms may be present, such as sensorineural hearing loss, cardiac malformations, and teeth alterations. Case description: 72-year-old female patient presented with left abundant spontaneous hyaline rhinorrhea, history of several bone fractures since early childhood, and a blue grayish sclera was noted. Cerebrospinal fluid (CSF) leak was diagnosed. Neuroimaging revealed lowering of the sella turcica floor, platybasia, basilar impression, left middle fossa calcified meningioma, syringobulbia, ventricular dilatation, and left ethmoidal fistula. Due to the patient’s age and clinical status, a medical approach was chosen, and treatment with acetazolamide and furosemide in low dosages, which resulted in a decrease of the rhinorrhea. Discussion: Clinical features and imaging study are often sufficient for diagnosis of OI. The neurological and cranial features in OI are varied. CSF leak is not commonly reported and might have been a consequence of bone softening and hydrocephalus. Conclusions: This case represents a treatment challenge, as the surgical results were uncertain, once bone fragility could result in the development of new leaks. Clinical treatment was chosen and resulted in a significant improvement of the symptoms.
Nocardiosis in Pets: First Reported Cases in Russia
Authors: Ovchinnikov Roman , Gaynullina Alla
Published: December 2019

Two cases of cutaneous nocardiosis in a cat and in a dog have been described. Diagnosis was made on basis of direct microscopy and cultural mycological analysis. Phenotypic characteristics of two indigenous Nocardia strains are presented. The strain isolated from cat was presumably identified as N. asteroids. There have been no reports of suchlike cases in pets in Russia so far.
Hypothetical Role of Large Nuclear Gravity in Understanding the Significance and Applications of the Strong Coupling Constant in the Light of Up and Down Quark Clusters
Authors: Seshavatharam U.V.S , Lakshminarayana S.
Published: December 2019

As there exist no repulsive forces in strong interaction, in a hypothetical approach, strong interaction can be assumed to be equivalent to a large gravitational coupling. Based on this concept, strong coupling constant can be defined as a ratio of the electromagnetic force and the gravitational force associated with proton, neutron, up quark and down quark. With respect to the product of strong coupling constant and fine structure ratio, we review our recently proposed two semi empirical relations and coefficients 0.00189 and 0.00642 connected with nuclear stability and binding energy. We wish to emphasize that- by classifying nucleons as ‘free nucleons’ and ‘active nucleons’, nuclear binding energy can be fitted with a new class of ‘three term’ formula having one unique energy coefficient. Based on the geometry and quantum nature, currently believed harmonic oscillator and spin orbit magic numbers can be considered as the lower and upper “mass limits” of quark clusters.
Less Cytotoxic Protoflavones as Antiviral Agents: Protoapigenone 1′-O-isopropyl Ether Shows Improved Selectivity Against the Epstein-Barr Virus Lytic Cycle
Authors: Vágvölgyi Máté , Girst Gábor , Kúsz Norbert , Otvos Sandor , Fülöp Ferenc , Hohmann Judit , Servais Jean-Yves , Seguin-Devaux Carole , Chang Fang-Rong , Chen Hao , Chang Li-Kwan , Hunyadi Attila
Published: December 2019

Protoflavones, a rare group of natural flavonoids with a non-aromatic B-ring, are best known of their antitumor properties. The protoflavone B-ring is a versatile moiety that may be explored for other pharmacological purposes, but common cytotoxicity of these compounds is a limitation to such efforts. Protoapigenone was previously found to be active against the lytic cycle of Epstein-Barr virus (EBV). Further, the 5-hydroxyflavone moiety is a known pharmacophore against HIV-integrase. The aim of this work was to prepare a series of less cytotoxic protoflavone analogs, and to study their antiviral activity against HIV and EBV. Twenty-seven compounds including 18 new derivatives were prepared from apigenin through oxidative de-aromatization and subsequent continuous-flow hydrogenation, deuteration, and/or 4′-oxime formation. One compound was active against HIV at the micromolar range, and 3 compounds showed significant activity against the EBV lytic cycle at the medium-low nanomolar range. Among these, protoapigenone 1′-O-isopropyl ether (6) was identified as a promising lead due to its 73-times selectivity of its antiviral over its cytotoxic effect, which exceeds that of protoapigenone by 2.4-times. Our results open new opportunities to design new, potent and safe anti-EBV agents based on the natural protoflavone moiety.
Cluster approach to sustainable tourism development
Authors: Allayorov Ravshan
Published: December 2019

The article considers the cluster approach to the sustainable development of tourism destinations. The concept of the "regional tourism cluster" and its features, as well as the symbol of the formation of the tourist group.
The Role of the Language Norm in the Definition Style Status
Authors: Zaripova Rano
Published: December 2019

This paper investigates major points of the the role of the language norm in the definition of stylist status. On this case, research was conducted both methodologically and practically. Literature review of the different scholars who studied this topic was also covered by the author. The way of conclusion is linked with vivid suggestions of the research directing to further investigations as the whole.
Budaya Organisasi dan Kepuasan Kerja dengan Motivasi Kerja Anggota Satlantas
Authors: Adhiyana Ferdyanzah Wira , Rini Rr. Amanda Pasca , Saragih Sahat
Published: December 2019

Work motivation in the organization has a close relationship with the willingness to complete the work properly. Such will is a form of encouragement that creates a passion for work. Positive work spirit is a useful factor in improving the ability to work. This research was conducted on member of Traffic Unit at Police of Sidoarjo with number of subjects of this study was 89 people. All subjects have long worked in the Traffic Police Sidoarjo unit at least 1 year with the rank of Bripda up to Aiptu. There is significant relation between organization culture and work statisfication with work motivation F = 38,691; p = 0,000) on member of traffic unit at police of Sidoarjo.
Hubungan antara Self Control dan Stres Kerja dengan Agresivitas Polisi
Authors: Putra Andra Purnama , Rini Rr. Amanda Pasca , Saragih Sahat
Published: December 2019

Aggression is a behavior that is intentionally to hurt,threaten, or endanger others or another object physically or verbal and direct or indirect. Aggression is a common characteristic that can’t be erase from human life, especially police. All police has it own aggression, but the capacity is different with others police depend on self control and work stress they have. The research purpose’s to know correlation of self control (X1) and work stress (X2) with police aggression (Y). It subject is sergeant policeman in Sidoarjo. Subject amount 120 Police. The sampel taken by purposive sampling method. Statistical analysis method that be used is regression and using SPSS 22.00 for windows. the first result is there is correlation between self control, work stress and Police aggression.the second result is there is correlation negatively between self control and aggression. The third result is there is correlation positively between work stress and aggression.
Marker-Based Method for Analyzing the Three-Dimensional Upper Body Kinematics of Violinists and Violists: Development and Clinical Feasibility
Authors: Wolf Edward , Möller Dirk , Ballenberger Nikolaus , Morisse Karsten , Zalpour Kristoff
Published: December 2019

AIMS: High string players (violin and viola) often suffer from musculoskeletal disorders. Although 3D motion analysis has proved helpful in diagnosing different musculoskeletal syndromes and identifying injurious movement patterns in violin and viola performance, more detailed analyses
of upper body movement strategies and especially of the shoulder complex have not yet been recorded. The use of spherical surface markers on some anatomical landmarks is, however, inappropriate when an instrument is being played. The aim of this study was to develop and evaluate a novel marker-based
method for analyzing upper body kinematics of high string players using conditions specific to violin and viola playing. METHODS: A custom upper body marker set was developed and a biomechanical model applied to 3D motion capture data of the pelvis, thorax, spine, head, and both upper limbs
(scapula, upper arm, forearm, hand) of 12 professional violinists, to assess its clinical feasibility. FINDINGS: Lumbar and thoracic spine, thorax, neck, and left upper limb were quite static, while extensive motion occurred in the right upper limb. Most rotation angles showed a reasonable
intersubject variability except for glenohumeral and wrist joints. Significant differences were observed between G- and D-string bowing, especially in the left wrist and right shoulder joints. INTERPRETATION: This study suggests that the proposed method is a valid tool for quantifying upper
body movements in violin and viola performance. With the extended upper body model, it will improve understanding of the motor strategies adopted by high string players and may contribute to injury prevention, diagnosis, and treatment.
De novo sequencing of the transcriptome of Fargesia macclureana (Poaceae) reveals regulators of the floral transition and ecological adaptations to high altitude
Authors: Li Ying , Zhang Chunxia , Yang Kebin , Shi Jingjing , Ding Yulong , Gao Zhimin
Published: December 2019

Background: Fargesia macclureana (Poaceae) is a woody bamboo species found on the Qinghai–Tibet Plateau (QTP) approximately 2,000 ~ 3,800 m above sea level. It rarely blossoms in the QTP, but it flowered 20 days after growing in our lab, which is in a low-altitude area outside the QTP. To date, little is known regarding the molecular mechanism of bamboo flowering, and no studies of flowering have been conducted on wild bamboo plants growing in extreme environments. Here, we report the first de novo transcriptome sequence for F. macclureana to investigate the putative mechanisms underlying the flowering time control used by F. macclureana to adapt to its environment. Results: Illumina deep sequencing of the F. macclureana transcriptome generated 140.94 Gb of data, assembled into 99,056 unigenes. A comprehensive analysis of the broadly, specifically and differentially expressed unigenes (BEUs, SEUs and DEUs) indicated that they were mostly involved in metabolism and signal transduction, as well as DNA repair and plant-pathogen interactions, which may be of adaptive importance. In addition, comparison analysis between non-flowering and flowering tissues revealed that expressions of FmFT and FmHd3a, two putative F. macclureana orthologs, were differently regulated in NF- vs F- leaves, and carbohydrate metabolism and signal transduction were two major KEGG pathways that DEUs were enriched in. Finally, we detected 9,296 simple sequence repeats (SSRs) that may be useful for further molecular marker-assisted breeding. Conclusions: F. macclureana may have evolved specific reproductive strategies for flowering-related pathways in response to photoperiodic cues to ensure long vegetation growing period. Our findings will provide new insights to future investigations into the mechanisms of flowering time control and adaptive evolution in plants growing at high altitudes.
Metabolite profile comparison of a graft chimera ‘Hongrou Huyou’ (Citrus changshan-huyou + Citrus unshiu) and its two donor plants
Authors: Zhang Min , Jing Luyang , Wu Qun , Zhu Kaijie , Ke Fuzhi , Xu Jianguo , Zhao Siqing , Wang Gang , Zhang Chi
Published: December 2019

Background: Chimeras synthesized artificially by grafting are crucial to the breeding of perennial woody plants. ‘Hongrou Huyou’ (Citrus changshan-huyou + Citrus unshiu) is a new graft chimera originating from the junction where a Citrus changshan-huyou (“C”) scion was top-grafted onto a stock Satsuma mandarin ‘Owari’ (C. unshiu, “O”). The chimera was named OCC because the cell layer constitutions were O for Layer 1(L1) and C for L2 and L3. In this study, profiles of primary metabolites, volatiles and carotenoids derived from different tissues in OCC and the two donors were investigated, with the aim of determining the relationship between the layer donors and metabolites.
Results: The comparison of the metabolite profiles showed that the amount and composition of metabolites were different between the peels and the juice sacs, as well as between OCC and each of the two donors. The absence or presence of specific metabolites (such as the carotenoids violaxanthin and β-cryptoxanthin, the volatile hydrocarbon germacrene D, and the primary metabolites citric acid and sorbose) in each tissue was identified in the three phenotypes. According to principal component analysis (PCA), overall, the metabolites in the peel of the chimera were derived from donor C, whereas those in the juice sac of the chimera came from donor O.
Conclusion: The profiles of primary metabolites, volatiles and carotenoids derived from the peels and juice sacs of OCC and the two donors were systematically compared. The content and composition of metabolites were different between the tissues and between OCC and the each of the two donors. A clear donor dominant pattern of metabolite inheritance was observed in the different tissues of OCC and was basically consistent with the layer origin; the peel of the chimera was derived from C, and the juice sacs of the chimera came from O. These profiles provide potential chemical markers for genotype differentiation, citrus breeding assessment, and donor selection during artificial chimera synthesis.
Quick selenium accumulation in the selenium-rich rice and its physiological responses in changing selenium environments
Authors: Liang Yuanke , Su Yang , Li Ling , Huang Xing , Panhwar Faiz Hussain , Zheng Tengda , Tang Zhichen , Ei Hla Hla , Farooq Muhammad Umer , Zeng Rui , Zhang Yujie , Ye Xiaoying , Jia Xiaomei , Zheng Lanlan , Zhu Jianqing
Published: December 2019

Background:The element selenium (Se) deficiency is thought to be a global human health problem, which could disperse by daily-supplement from Se-rich food. Increasing the accumulation of Se in rice grain is an approach matched to these nutrient demands. Nonetheless, Se is shown to be essential but also toxic to plants, with a narrow margin between deficiency and toxicity. Notably, the regulatory mechanism balancing the accumulation and tolerance of Se in Se-rich rice plants remains unknown. Results:In this study, we investigated the phenotypical, physiological, and biochemical alterations of Se-rich rice in the exposure to a variety of Se applications. Results showed that the Se-rich rice was able to accumulate more abundance of Se from the root under a low Se environment comparing to the Se-free rice. Besides, excessive Se led to phytotoxic effects on Se-rich rice plants by inducing chlorosis and dwarfness, decreasing the contents of antioxidant, and exacerbating oxidative stresses. Furthermore, both phosphate transporter OsPT2 and sulfate transporters OsSultr1;2 may contribute to the uptake of selenate in rice. Conclusions:Se-rich red rice is more sensitive to exogenous application of Se, while and the most effective application of Se in roots of Se-rich rice was reached in 20μM. Our findings present a direct way to evaluate the toxic effects of Se-rich rice in the Se contaminated field. Conclusively, some long-term field trial strategies are suggested to be included in the evaluation of risks and benefits within various field managements.
Autologous plasma versus fetal calf serum as a supplement for the culture of neutrophils.
Authors: Alipour Razieh , Fatemi Alimohammad , Alsahebfosul Fereshteh , Andalib Alireza , Pourazar Abbasali
Published: December 2019

Objective

Currently the replacement of fetal calf serum (FCS) by a more suitable alternative is a sought aim in the field of tissue and cell culture research. Autologous plasma (AP) and especially autologous serum (AS) have been shown to be effective substitutes of FCS in culture media for some of cell types. Nevertheless, there is no comparative data on the most appropriate supplement for cell media in neutrophil studies, it is now unclear whether AP have relatively an equal, superior or inferior performance to FCS in neutrophil cell culture. In the present study, human blood neutrophils were isolated and cultured in FCS- or AP-supplemented medium. After 12, 36 and 60 hours of incubation, cell viability, oxidative burst and CD11b expression were determined by flow cytometry.Results

Compared to the culture of neutrophils in FCS 10% medium, the culture of neutrophils in a medium with AP 10% could prolong their life span without affecting their function. The findings introduce AP as a better supplement for human neutrophil cell culture than FCS and propose a simple and economical procedure for neutrophil isolation and culture.
Association of Daily Copayments with Use of Hospital Care among Medicare Advantage Enrollees
Authors: McHugh John , Keohane Laura , Grebla Regina , Lee Yoojin , Trivedi Amal
Published: December 2019

Background: While the traditional Medicare program imposes a deductible for hospital admissions, many Medicare Advantage plans have instituted per-diem copayments for hospital care. Little evidence exists about the effects of changes in cost-sharing for hospital care among the elderly. Changing inpatient benefits from a deductible to a per diem may benefit enrollees with shorter lengths of stay, but adversely affect the out-of-pocket burden for hospitalized enrollees with longer lengths of stay. Methods: We used a quasi-experimental difference-in-differences study to compare longitudinal changes in proportion hospitalized, inpatient admissions and days per 100 enrollees, and hospital length of stay between enrollees in MA plans that changed inpatient benefit from deductible at admission to per diem, intervention plans, and enrollees in matched control plans – similar plans that maintained inpatient deductibles. The study population included 423,634 unique beneficiaries enrolled in 23 intervention plans and 36 matched control plans in the 2007-2010 period. Results: The imposition of per-diem copayments were associated with adjusted declines of 1.3 admissions/100 enrollees (95% CI -1.8 to -0.9), 6.9 inpatient days/100 enrollees (95% CI -10.1 to -3.8) and 0.7 percentage points in the probability of hospital admission (95% CI -1.0 to -0.4), with no significant change in adjusted length of stay in intervention plans relative to control plans. For persons with 2 or more hospitalizations in the year prior to the cost-sharing change, adjusted declines were 3.5 admissions/100 (95% CI -8.4 to 1.4), 31.1 days/100 (95% CI -75.2 to 13.0) and 2.2 percentage points in the probability of hospitalization (95% CI -3.8 to -0.6) in intervention plans relative to control plans. Conclusions: Instituting per-diem copayments was associated with reductions in number of admissions and hospital stays, but not length of stay once admitted. Effects of inpatient cost-sharing changes were magnified for persons with greater baseline use of hospital care.
Practice, Perceived Barriers and Motivating factors to medical-incident reporting: A cross-section survey of health care providers at Mbarara Regional Referral Hospital, Southwestern Uganda.
Authors: Turyahabwe Naome , Mwesigwa James , Atuhairwe Christine , Taremwa Ivan Mugisha
Published: December 2019

Background Medical-incident reporting (MIR) ensures patient safety and delivery of quality of care by minimizing unintentional harm among health care providers. We explored medical-incident reporting practices, perceived barriers and motivating factors among health care providers at Mbarara Regional Referral Hospital (MRRH).Methods We conducted a cross-sectional study on 158 health provider at Mbarara Regional Referral Hospital (MRRH), Western Uganda, using a structured questionnaire and analyzed the data obtained using SPSS. The chi-square was used to test for association and principle component analysis was used to establish with the highest correlation with MIR at MRRHResults The results showed that there was no formal incident reporting structure. However the medical-incidences identified were: medication errors (89.9%), diagnostic errors (71.5%), surgical errors (52.5%) and preventive error (47.7%). The motivating factors of MIR were: establishment of a good communication system, instituting corrective action on the reported incidents and reinforcing health workers knowledge on MIR (p-value 0.004); presence of effective organizational systems like: written guidelines, practices of open door policy, no blame approach, and team work were significantly associated with MIR (p-value 0.000). On the other hand, perceived barriers to MIR were: lack of knowledge on incidents and their reporting, non-existence of an incident reporting team and fear of being punished (p value 0.669).Conclusion Medical Incident Reporting at MRRH was sub-optimal. Therefore setting up an incident management team and conducting routine training MIR among health care workers will increase patient safety.