bluuebunny/crossref_metadata_2025 huggingface dataset:
Projeto como Instrumento de Ensino-Aprendizagem para Integração de Saberes
Authors: Barcellos de Souza Gisela , Magiag Loura Rejane , Dos Santos Roberto E.
Published: February 2024

O artigo discute a convergência de conteúdos no ensino de projeto em Arquitetura e Urbanismo, com ênfase em estratégias e instrumentos de integração não hierarquizada dos saberes e no desenho de ambiente de ensino e aprendizagem orientado para a interação não programada em contexto remoto. O texto está organizado em três partes. Primeiro, discute-se do lugar do projeto no ensino de arquitetura e urbanismo. Na segunda parte, apresentam-se e avaliam-se as estratégias e instrumentos desenvolvidos para integração não hierarquizada entre os saberes. Por último, examina-se o desenho do ambiente de ensino-aprendizagem orientado para a interação não programada. Trata-se de uma análise da Oficina Virtual Integrada, experimento realizado no contexto do Ensino Remoto Emergencial para enfrentamento das restrições impostas pelo isolamento social como medida de contenção da pandemia de COVID-19, ministrada em três edições na Escola de Arquitetura da UFMG entre 2020 e 2021. O experimento promoveu a concepção e a avaliação de estratégias para articulação entre os saberes e de ambiente de ensino-aprendizagem voltado à valorização do projeto como processo de invenção e ao trabalho colaborativo e compartilhado de orientações. Sua realização reitera a identificação da contradição entre a lógica administrativa e as demandas da formação integral e aponta para o necessário aprofundamento das questões levantadas e para a atenção à especificidade dos arranjos locais.
ILUMIARAS:
Authors: Vargas Rodrigues Gabriela , Bezerra Fernandes Ramon , Rafael Melo Teixeira Jonas , Helena Nogueira Isadora , Carvalho Colque Ana Camille
Published: February 2024

O ateliê virtual denominado “International Virtual Architectural Design Studio - IVADS”, ocorrido durante o 11º Seminário Internacional Projetar, teve a intenção de desenvolver um concurso de ideias com foco em intervenções em preexistências de valor patrimonial seguindo os princípios da criação de espaços para a economia criativa. Este artigo descreve o progresso de uma das equipes, a Equipe “Ilumiaras”, teve como objetivo central intervir em bens edilícios de valor cultural do centro histórico da cidade de João Pessoa-PB com o intuito de valorizar a comunidade local como ferramenta de desenvolvimento socioeconômico e de preservação do patrimônio do sítio. A equipe reuniu alunos de Arquitetura e Urbanismo no contexto da graduação e da pós-graduação, além de docentes provenientes da Universidades Federais da Paraíba (UFPB), de Pernambuco (UFPE), do Rio Grande do Norte (UFRN) e Universidade de Lisboa (ULisboa). Nesse sentido, o processo projetual foi marcado pela conceituação desde a escolha do nome da equipe até o partido do projeto; discussões sobre o referencial teórico utilizado e o foco nos valores e virtudes do local que o objeto de estudo está inserido; e desenvolvimento da proposta, explicitando as limitações e competências constatadas. Esse projeto contribuiu para as discussões sobre a formulação de ideias propositivas em equipes colaborativas multi institucionais e sobre a prática projetual em áreas de valor patrimonial, além do foco em projetar para incentivar a economia criativa. A equipe Ilumiaras concluiu que o concurso propiciou uma melhor compreensão de processo de projeto para concursos, com suas limitações e desafios.
VIVA VARADOURO
Authors: AGUIAR CAIO HENRIQUE GOMES DE , DIAS ISLENA MELO DE CARVALHO , Alexandre Neto Antonio
Published: February 2024

O presente artigo discorre sobre a produção de uma proposta de intervenção no Centro Histórico de João Pessoa (PB) como resposta ao concurso de ideias desenvolvido no Ateliê Virtual Internacional de Projeto de Arquitetura – IVADS de 2023. O projeto foi desenvolvido por uma equipe de alunos de graduação, monitores de pós-graduação e docentes orientadores, pertencentes a quatro instituições de ensino: UFRN, UFPB, UFPE e ULisboa. O trabalho está estruturado em três partes, contemplando uma breve contextualização do local intervisto, as ideias iniciais e o processo projetual e, por fim, o produto final apresentado. As decisões projetuais tomadas pela equipe se basearam em estudo bibliográfico acerca da temática de proposições de intervenção na preexistência, elencando aspectos fundamentais para a proposição projetual em respeito ao edificado patrimonial, bem como para a concepção de ambientes criativos. Os resultados apontam estratégias de projeto que aproximam a vivência do centro histórico com a economia criativa, por meio de soluções aplicadas em todo o conjunto edificado, assim como na praça localizada no entorno imediato. Ademais, o produto final reforça a importância da comunicação e da interligação entre os fluxos de pedestres e as diversas possibilidades de uso que podem ocorrer no local de intervenção, como pontos norteadores de uma proposição adequada à realidade local.
Overview of Nanotechnology Applications in Healthcare
Authors: Praful T.R.
Published: February 2024

Microorganisms gaining drug resistance, difficulty in disease screening, unavailability of point-of-care diagnostic tools are few challenges in the healthcare industry. Over the past few decades, much research has been directed towards developing new nanomaterials with tunable properties for diverse applications in biomedicine, bioimaging, disease diagnosis, therapeutic formulations, etc. Nanosystems specifically used in the healthcare sector include specially designed and functionalized nanomaterials for suitable applications. Nanotechnology finds important applications in identification of specific types of cancers even before their onset, identification of specific infections, targeted gene and drug delivery systems, etc.
Nanoparticles in Glioma Therapy and Drug Delivery Systems
Authors: Bhanu Revathi K
Published: February 2024

Gliomas are tumours of the glial cells of the brain, and they are highly complicated in terms of treatment, recovery, and diagnosis. Some of them are high grade tumours that require sophisticated imaging tools for diagnosis. Nanoparticles offer many advantages as targeted drug delivery systems causing minimal harm to the surrounding tissues and higher bioavailability at the site of the tumour. This chapter aims in exploring the various treatment methods and the possibility of using cellular macromolecules as targets for drug delivery. Combinatorial approaches along with nanoparticles are required to minimise the recurrence of tumour and to enhance patient recovery in various types of gliomas.
Approaches in Synthesis, Fabrication, and Toxicity of Plant-based Nanomaterials
Authors: Gayathri V.
Published: February 2024

Plants contain a wide range of phytochemicals, including flavonoids, alkaloids, tannins, saponins, and other metabolites. The nanomaterials have significant implications in current therapeutic approaches for various diseases, including cancer. Herbal extracts offer a safer pathway for the generation of nanomaterials, as the secondary metabolites present in these extracts act as stabilizing and reducing agents, leading to the formation of nanoparticles (NPs). These plant extract-derived NPs find diverse applications in various fields, particularly in nanomedicine. This review focuses on the recent advancements in the biomedical applications of such nanomaterials, specifically for cancer treatment and combating viral infections.
Nano Antibiotics: Prospects and Challenges
Authors: Jayachandran J.P.
Published: February 2024

Antibiotic resistance is a major global public health concern, resulting in high healthcare costs, increased morbidity, and mortality. With a limited number of new antibiotics being developed, the emergence and spread of antibacterial resistance poses a constant threat to public health. After 1980s the antibiotic pipeline began to dry up and fewer new drugs were introduced, and microbes seem to be on the winning side in tiding over the barricades built by drugs. Adoption of an effective strategy to intervene the burning issue of MDR is a necessity of the hour. Nanotechnology gives great hope to the medical community in their fight against pathogens. As an essential byproduct nanoantibiotics (nAbts) are being developed by conjugating nanoparticles with antibiotic molecules. Various types of nanoparticles are used as drug delivery systems. This chapter explores the prospects of nAbts, the composition and types of nAbts, their mode of action, challenges faced by nAbts in terms of safety, toxicity, manufacturing complexity, regulatory hurdles etc. as well as development of resistance among bacterial pathogens against nAbts.
Diagnostic Nanotechnologies
Authors: Chandrasekharan D.K.
Published: February 2024

The application of nanotechnology in clinical diagnostic purposes can be defined as nanodiagnostics. Since most of the biological molecules as well as cell organelles fall within the nano scale, nanotechnology can assure to meet the rigorous demands being put forth by the clinical laboratory in terms of sensitivity, earlier and faster detection of diseases and cost-effectiveness. Nanotechnology Based Diagnostics or Nanodiagnostics is also termed as "molecular imaging" and it is an evolutionary leap in diagnostic imaging. Nanodiagnostics assays are utilized in immunoassays, DNA diagnostics, imaging, etc for the detection of tumors and infectious diseases.
Green Synthesis of Nanoparticles via Plant Extract: A New Era in Cancer Therapy
Authors: Saad Kirti
Published: February 2024

There are many potential applications for the production of green nanoparticles (NPs) in medical and environmental sciences. Green synthesis is focused on minimizing the use of harmful chemicals. Scientists are working to create unique approaches for treatment and diagnostics of cancer in light of development of the newest technology. Primarily plant-based approaches have been chosen as the best course of action due to benefits of biogenic approaches over traditional synthesis, including their simplicity, speed, energy efficiency, one-pot operations, safety, economics, and biocompatibility. The finest sources of biogenic NPs are secondary metabolites that operate as stabilizers or reducers to form NPs. Here, we discuss the role of plant mediated NPs for cancer therapy.
Future Directions in Nanomaterials Research for Biological Applications
Authors: Das R.
Published: February 2024

Nowadays, nanomaterial-based technologies have reached a great height from the application point of view. However, this chapter is mainly focused on nanomaterials research for biological applications and its future directions. Depending on the shape, size and elemental composition, nanomaterials are capable of exhibiting some unique and remarkable functional properties. Due to such functional properties, nanomaterials have attracted much attention for biomedical applications and are being tested for easier treatment and diagnosis without any side effects. This chapter not only provides the expected biological applications of nanomaterials but also points out some information starting from key properties of biologically applicable nanomaterials to characterization through fabrication processes.
Cardiovascular Toxicity of Nanoparticles
Authors: Thakur A.
Published: February 2024

The integration of nanotechnology into various industries has raised concerns about potential health risks, particularly regarding cardiovascular toxicity. This book chapter comprehensively examines the impact of nanoparticles on the cardiovascular system, elucidating the underlying mechanisms and critical factors influencing toxicity. It reviews the current state of research on nanoparticle exposure via different routes, such as inhalation and ingestion, and their subsequent distribution in the cardiovascular system. Furthermore, the chapter delves into the cellular and molecular events triggering adverse cardiovascular effects, including oxidative stress, inflammation, and endothelial dysfunction. Understanding these toxicological aspects is crucial in developing effective safety guidelines and tailored nanomedical interventions for safer nanotechnology applications.
Cage Structured Compounds
Authors: Gupta Anita
Published: February 2024

This chapter has targeted the features of inorganic cage compounds, their classification, and their overabundant applications. The term ‘Cage’ is utilized as a specific term for three-dimensional structures which have a definite and rigid geometry. There can be various atomic positions in the cage, these positions can operate as branching origins and additional ligands can be introduced at these positions. Recent advances in the synthetic chemistry and strategies adopted for the synthesis of cage compounds with special attention to Calixarenes and Cryptophanes have played an analytical role in the development of Biomedical Applications, drug freightage systems, sensing, bio-imaging, and other smart materials. The adsorption of dye from industrial wastewater by the functionalized Calixarene cage e.g. Dinitro Calix [4] arene cage (DNCC) was tested for the first time [1]. Recent research indicates that Cryptophane cages can also adopt different configurations and demonstrate various applications [2]. During the 1970s, a founding work by Corbett and Simon on rare-earth halides led to the establishment of the fact that these highly cluster skeleton electron-deficient clusters always involve an interstitial atom inside the metal cluster cage. A novel development in the field of coordination chemistry of integral cage molecules and their ligand complexes has been extensively researched for their budding application as building blocks in polymers [3]. Caged structure complexes, one of its kind in supramolecular chemistry have always garnered the attention of the scientific community worldwide. This book chapter is an initiative to instill the essence of the caged compound with its striking features and a plethora of applications.
História Centenária da Associação de Futebol de Braga
Authors: Fernandes João M.
Published: February 2024

Este livro apresenta um primeiro capítulo em que se faz um enquadramento geográfico e social do distrito de Braga, para se perceber o contexto em que a AFB realiza a sua missão. No segundo capítulo, apresenta-se um resumo dos 100 anos de vida da AFB, discute-se a forma como se processou a fundação da associação, enumeram-se as sedes e descrevem-se os factos mais relevantes de cada uma das épocas entre 2011/12 e 2021/22. O terceiro capítulo é integralmente dedicado a todos os clubes da AFB, as células básicas que a compõem e lhe dão força e vida. Seguem-se os capítulos 4 e 5 sobre jogadores e treinadores, ligados ao contexto, seja geográfico seja clubístico, da AFB. O 6.º capítulo trata dos presidentes da AFB, o mais alto cargo de responsabilidade. O sector da arbitragem é tratado no capítulo seguinte. O capítulo 8 aborda as seleções distritais, com destaque para aquelas que jogaram nas décadas de 1920, 1930 e 1940, um período muito rico nesse tipo de iniciativa. O conteúdo deste 8.º capítulo apresenta muito material que não foi abordado nos três livros anteriores da AFB. Os capítulos finais fazem referências ao futsal, modalidade que tem na AFB forte expressão, e à vertente feminina do futebol. Do ponto de vista temático faria sentido existir um capítulo sobre o futebol de praia, mas dado o escasso número de clubes que o praticou ou pratica acabou por se optar pela sua não inclusão.
The Old Frisian MASC.SG. form of the proximal demonstrative pronoun this
Authors: Versloot A.
Published: February 2024

The ACC.SG.MASC. form of the Old Frisian proximal pronoun 'this', thissen, does not appear in the earliest Old Frisian texts. Ms. B2 contains five instances of thenne with a proximal meaning, alongside the form thene as form of the definite article in the same fragment. This rare form of the proximal pronoun, which resembles Old Norse þenna, is corroborated by 19th c. Wangerooge Frisian din 'this (MASC.)'. The form thenne is frequent in Old West Frisian in the Unia version of the Old Skelta-law, where it appears as an archaic equivalent to the article thine; the latter is the default in younger Unia texts. It is hypothesised that incipient, incidental weakening of the geminate realisation in unstressed pronouns in pre-Old West Frisian, together with the existence of analogical patterns in the ACC.SG.MASC. forms minne, thinne, sinne, enna/anne 'my, thy, his, one', provoked a merger of the proximal form thenne with the much more frequent article thene. Eventually, when geminates were lost in unstressed syllables in the early 14th c., thenne disappeared and thine – independently developed from older thene or (re)created by analogy with the anaphoric pronoun hine – became the sole form of the ACC.SG.MASC. article in late Old West Frisian. A new analogical form of the proximal pronoun thissen was created in the 14th c.
Pengembangan Bahan Ajar E-Handout Berbasis Kodular untuk Sekolah Dasar Fase C pada Mata Pelajaran Bahasa Indonesia
Authors: Latip Asep Ediana , Putri Kinanti Adlina , Hokiani Friski
Published: February 2024

This study aims to determine the validity and feasibility of products in the form of codular-based e-handouts that are usable, valid, practical, and effective in understanding Indonesian language subjects in phase C. This research is included in the Research and Development (R&D) development model in the form of ADDIE which consists of five stages of development namely analysis, design, development, implementation, and evaluation. The subjects in this study were instrument validators. All results of data analysis using the validity index assessment aspects of Aiken. With the results of data analysis in the aspect of validity obtained from the material expert test of 3 statements with a validity index value status of 0.5, 3 statements with a validity index status of 0.75, and 1 statement with a validity index value status of 1.00. Based on the validity index criteria from Aiken's validity of the design expert's score, the 3 value statements are included in the revision criteria, and 4 statements are in the valid criteria. According to the accumulation of assessments from design expert validators, it shows that this Kodular-based e-handout teaching material is suitable for use in learning with some notes that must be revised. The calculation results obtained from design experts based on the validity index from Aiken are 2 statements with a validity index value status of 0.5, and 5 statements with a validity index status of 0.75. Based on the validity index criteria from Aiken, the validity of the linguist's score, the 2 statements are included in the revision criteria, and 5 statements are in the valid criteria. It can be concluded that the development of codular-based e-handot teaching materials is valid and feasible to use for Indonesian language subjects in phase C.

Keyword: teaching materials, codular, indonesian language
Penerapan Model Pembelajaran Kooperatif Tipe MAM (Make A Match) terhadap Kemampuan Berpikir Kreatif Siswa Kelas III MI Al-Muhsin 1 Krapyak
Authors: Yatimah Durrotun , Sukati Sukati , Maksum Khanif
Published: February 2024

This research is motivated by the learning has not been varied, the interest in learning owned by third grade students of MI Al-Muhsin 1 is still low so that it affects the ability to think creatively. The learning of MI Al-Muhsin 1 Krapyak has never applied the cooperative learning model of make a match type, especially on theme 8 subtheme 1 lesson 2 of Ppkn subject The purpose of this research is to: 1) Describe the application of cooperative learning model of make a match type in creative thinking ability of third grade students of MI Al-Muhsin 1 Krapyak; 2) Knowing the application of cooperative learning model of make a match type can improve the creative thinking ability of third grade students of MI Al-Muhsin 1 Krapyak.

This research is a quantitative research with quasi-experimental type. The population of this research was all third grade students of MI Al-Muhsin 1 Krapyak with 20 students of class IIIA (experimental class) and 20 students of class IIIB (control class). Sampling is by simple random sampling or random sample, data collection techniques with test and observation techniques.

The results showed that; 1) The application of cooperative learning model of make a match type to the creative thinking ability of third grade students of MI Al-Muhsin 1 Krapyak is running smoothly in accordance with the lesson plan that the creative thinking ability of students obtained pre test value 100% (20 people) students think creatively with good category and post test value obtained 85% (17 people) students have creative thinking ability.

Keywords: learning model, make a match, creative thinking

 
Identification and functional characterization of novel inflammation-associated genes differentially expressed by pulmonary arterial hypertension patients:Method (Preprint)
Authors: He Yaqin
Published: February 2024

BACKGROUND

Pulmonary arterial hypertension (PAH) is a severe disease with high mortality. The characteristics of PAH pathology include pulmonary arterial vasoconstriction and vascular remodeling, subsequently leading to right ventricular dysfunction and right heart failure. Recent advancement in clinical and experimental studies have documented that multiple types of immune cells are recruited to and accumulated in the PAH lungs, and high levels of inflammatory mediators have been observed in both vascular remodeling environment and circulation of PAH patients, demonstrating that inflammation plays an important role in vascular remodeling in PAH. How the immune cells crosstalk with other cells involved in the process of vascular remodeling is unclear.

METHODS

Single cell sequencing and bulk transcriptome database associated with PAH were obtained from Gene Expression Omnibus (GEO). GSE154959 was used for single cell sequencing analysis, data set of GPL6244 was used for target cell annotation. For model construction and Hub gene identification, PAH patient databese GSE117261 was used as the training set, and GSE113439 as the verification set. STRING was used for protein-protein interaction analysis, and CIBERSORT algorism was used for immune cell and inflammatory mediator analysis. The hub genes identified were further characterized by gene set enrichment analysis (GSEA) to illustrate their signal pathways, and by Cistrome DB for their transcription factor network. The receiver operating characteristic (ROC) curves were analyzed for evaluating and validating the diagnostic values of the hub genes.

RESULTS

Four Hub genes differentially expressed by PAH immune cells were identified. The correlation of these genes with immune cell infiltration and inflammatory mediator secretion in PAH were established. The diagnostic value of these genes was evaluated and validated with PAH patient data, and the signaling pathways of the hub genes potentially associated with inflammation of the pathology process of PAH were defined.

CONCLUSIONS

In this study, we have identified four Hub genes associated with PAH through machine learning algorisms coupled with bioinformatics methods. These genes were differentially expressed by immune cells of PAH lungs, and highly correlated with immune cell infiltration and inflammatory mediator secretion. The genes were enriched in multiple signal pathways characteristic of inflammation and fibrosis and have diagnostic values of high confidence as validated using PAH patient data from GSE113439 database.

CLINICALTRIAL

None
Чи є положення лежачи на животі безпечним для органів ризику при променевій терапії молочної залози? Клінічний випадок та огляд літератури
Authors: Oz Sumeyra , Sabah Aslı , Kılınc Ilyas Anıl , Bascik Oguzhan , Babayigit Yunus , Sucak Ipek , Celik Yasemin , Kurtman Cengiz
Published: February 2024

Ад’ювантна променева терапія є важливою у хворих на рак молочної залози, однак її довгострокові ускладнення є проблемою, особливо для серця та легенів. Описано випадок раку в 77-річної пацієнтки, якій виконано операцію зі збереження грудей та ад’ювантну променеву терапію. Жінка мала великі відвислі тканини молочної залози, тому комп’ютерну томографію проведено в положенні лежачи на животі або на спині. Оскільки в нашій клініці не було спеціального пристрою, за допомогою блоків із пінополістиролу та ліжка з нахилом ми розробили механізм для проведення радіотерапії в положенні пацієнтки лежачи на животі. Завдяки цьому знижується променеве навантаження на серце та легені, без шкоди для зони охоплення. Таким чином, радіотерапія в положенні лежачи є ефективним методом у пацієнток із раком молочної залози, тому в кожному випадку слід оцінювати, яким положенню та методу буде віддано перевагу
Профілактика та лікування периферичної нейропатії, індукованої хіміотерапією (огляд літератури)
Authors: Hannotska A.Yu. , Zotov O.S.
Published: February 2024

Периферична нейропатія (ПН), спричинена хіміотерапією, є поширеним побічним ефектом терапії раку, який може мати глибокий вплив на якість життя та виживання. Частота виникнення ПН залежить від хіміотерапевтичного засобу, дози та тривалості впливу. Найчастіше засобами, що індукують ПН, є препарати платини, особливо цисплатин і оксаліплатин, таксани та алкалоїди барвінку. Завдяки успіхам протипухлинної терапії очікується, що кількість вилікуваних пацієнтів зростатиме. Отже, тривала нейротоксичність є важливою проблемою для осіб, що отримували таке лікування, особливо з приводу раку молочної залози та/або товстої кишки. Крім того, периферична нейропатія, індукована хіміотерапією, може негативно впливати на результати лікування через вимушену зміну дози та/або передчасне припинення лікування. Однак, незважаючи на значну поширеність, ПН часто діагностується і лікується незадовільно. У цьому огляді буде розглянуто існуючі методи профілактики та лікування периферичної нейропатії, індукованої хіміопрепаратами.
The Legal Protection Path of Intangible Cultural Heritage of Ethnic Minorities Beyond the Framework of Intellectual Property Rights
Authors: Wu Xueping
Published: February 2024

For the legal protection of intangible cultural heritage of ethnic minorities, China has basically formed a legal protection mode combining international legal protection with domestic legal protection, and combining public law protection with private law protection. However, the protection of intangible cultural heritage by the intellectual property system is concentrated in two aspects: creative products (works) based on traditional knowledge and traditional skills that have not yet been disclosed and can be applied in industry. The protection of intangible cultural heritage of ethnic minorities is facing the dilemma of limited compatibility of intellectual property rights. Therefore, we should clarify the protection ideas of intangible cultural heritage of ethnic minorities, go beyond the framework of intellectual property rights, and form a diversified protection path of intangible cultural heritage of ethnic minorities.
Jayadeva’s Gita Govinda: a poem about the agony and separation of Lord Krishna and his beloved Radha
Authors: Kharyal Priya
Published: February 2024

Love is not merely an emotion but a potent feeling everyone desires to experience. When someone falls in love, they lose control over their feelings. Some individuals love selflessly, even without any hope for reciprocation. We all wait for someone who makes us feel unique and adds extraordinary value to our lives. However, love also demands sacrifices; sometimes, our love becomes the reason for someone's pain. In love, one should not be selfish and should not expect reciprocation from the other person. Love is unconditional and knows no bounds. "If someone does not love you, you do not have to convince them to love you back. True love comes naturally when you truly care for someone. Only when someone who loves you disappears from your life do you realise their importance? In contemporary times, everyone desires to be loved and to love in return. We are all lonely people who crave love and care. No one can love someone like Radha loved Lord Krishna. “Their love is everlasting and serves as an example of true love for future generations. Their love, respect, and care for each other cannot be matched. This paper will analyse the theme of love by examining the story of Lord Krishna and his beloved Radha and their love and sacrifice for each other."
Automated Waste Sorting System
Authors: Sontakke Prof. Sneha R.
Published: February 2024

Abstract: Managing solid waste through recycling is a crucial measure to mitigate adverse effects like sanitation and health issues arising from excessive landfill usage. However, the intricacies and costs associated with sorting solid waste pose challenges to recycling efforts. To streamline this process, our study proposes a Deep Learning approach employing computer vision to automatically recognize and categorize waste into five primary types: plastic, metal, paper, cardboard, and glass. Our conceptual system entails an automated recycling bin that opens its lid corresponding to the identified waste type. The primary focus of our work lies in the development and optimization of Machine Learning algorithms for efficient waste identification. We utilized pre-existing images to train a minimum of 12 variants of the Convolutional Neural Network (CNN) algorithm across three classifiers: Support Vector Machine (SVM), Sigmoid, and SoftMax. Our findings reveal that the VGG19 model with a SoftMax classifier achieves an accuracy of approximately 88%.
Decision Making in Monopoly Using a Hybrid Deep Reinforcement Learning Approach
Authors: Parihar Hitesh , M Suman
Published: February 2024

Abstract: This research introduces a novel approach to decision-making in the classic board game Monopoly by leveraging a hybrid deep reinforcement learning framework. Traditional methods for decision-making in Monopoly often rely on heuristic strategies or rule-based systems, which may lack adaptability and fail to capture the dynamic and complex nature of the game. In contrast, this study proposes a hybrid model that combines the strengths of deep learning and reinforcement learning to enable an agent to autonomously learn effective decision-making strategies through interactions with the Monopoly environment. The hybrid deep reinforcement learning model is designed to process and interpret the intricate game state representations, learning optimal decision policies over time. The incorporation of deep neural networks allows the model to capture complex patterns and dependencies in the data, while reinforcement learning enables the agent to iteratively improve its decision-making abilities through trial and error. The research focuses on developing a suitable reward structure and feature representation that enhances the model's ability to navigate the diverse scenarios encountered in Monopoly, ultimately aiming to achieve superior decision-making performance compared to traditional approaches.
Analisa Performansi Controller Pada Arsitektur Jaringan Software Defined Network (SDN)
Authors: Rahmawan Agung Dwi , Syaifuddin Syaifuddin , Risqiwati Diah
Published: February 2024

Software Defined Network (SDN) merupakan sebuah konsep pendekatan baru dalam jaringan untuk mendesain, membangun serta mengelola suatu jaringan komputer. Konsep ini melakukan pemisahan terhadap Data Plane dan Control Plane. Dalam konsep SDN ini terdapat suatu komponen penting yang bertanggung jawab terhadap segala aturan dalam pengelolaan dan pendistribusian informasi terhadap seluruh perangkat jaringan yaitu Controller. Karena peran Controller yang penting maka performa dari Controller perlu diuji sehingga dapat mengetahui kemampuan dari Controller yang digunakan. Dalam penelitian ini dilakukan perbandingan analisis nilai Quality of Services (QoS) terhadap implementasi SDN menggunakan Controller Floodlight dan Ryu dengan menjalankan topologi linear dan mesh dalam jumlah Switch yang beragam mulai dari 4, 8, 12 dan 16 Switch. Selama pengujian berlangsung dari node sumber ke node tujuan yang sama juga dialiri variasi background traffic mulai dari 50 hingga 200 Mbps. Hasil yang didapatkan yaitu Controller Ryu memiliki nilai QoS yang lebih baik dari floodlight pada semua topologi yang diujikan, nilai latency dan jitter pada floodlight lebih tinggi dari ryu serta cenderung meningkat pada traffic 100 Mbps Pada throughput, ryu memiliki nilai lebih tinggi dengan kisaran 856-933 Kbps. Sedangkan pada packet loss floodlight lebih tinggi sementara ryu hanya memiliki rata-rata packet loss sebesar 0,5%. Namun pada pengujian hanya pada jumlah switch, floodlight menjamin dalam tingkat respons serta pengelolaan data yang besar di dalam arsitektur jaringan SDN.
Rancang Bangun Alat Pendeteksi Jarak Aman, Intensitas Cahaya, dan Waktu Ideal Pengguna Laptop
Authors: Utama Shoffin Nahwa , Musthafa Aziz , Syahrin Moch Alfi
Published: February 2024

Laptop merupakan suatu perangkat yang banyak digunakan oleh semua kalangan baik muda maupun orang tua. Penggunaan internet yang semakin popular dapat menyebabkan para pengguna menghabiskan waktu di depan laptop dengan berjam-jam. Berada di depan laptop yang terlalu lama dapat memberikan dampak pada indra penglihatan yaitu mata. Selain itu layar monitor memancarkan sinar-x yang dapat mengganggu kesehatan mata. Untuk mengurangi dampak penggunaan laptop, harus memperhatikan jarak aman, intensitas cahaya dan waktu ideal saat menggunakan laptop. Tujuan dari penelitian adalah untuk merancang alat pendeteksi jarak aman, intentias cahaya dan waktu ideal ketika sedang beraktivitas menggunakan laptop. Rancangan alat ini mampu memberikan peringatan bila jarak dan cahaya telah melewati nilai ambang batas standar yang telah ditentukan. Rancangan alat ini dilengkapi Mikrokontroler Arduino Uno sebagai kendali utama, Sensor Ultrasonik sebagai pendeteksi jarak kurang dari 50 cm, Sensor Intensitas Cahaya sebagai pendeteksi cahaya sekitar minimal 100 lux dan maksimal 300 lux, Lcd Oled sebagai informasi untuk menampilkan waktu ideal yang telah ditentukan selama 4 jam serta memberikan peringatan berupa tulisan, jika masing-masing sensor mendeteksi nilai ambang batas yang telah ditentukan. Indikator peringatan pada rancangan dilengkapi dengan dua buah peringatan yaitu Lampu LED dan Buzzer. Buzzer berbunyi apabila pengguna terlalu dekat dengan layar laptop. Sedangkan bunyi buzzer dan LED menyala, apabila intensitas cahaya yang diterima gelap dan terlalu terang. Jika waktu berakhir maka buzzer dan lampu LED akan menyala sampai tombol off dimatikan. Pengujian rancangan ini menggunakan uji coba eksperimen. Hasil uji coba menunjukkan bahwa rancangan dapat mendeteksi jarak pengguna dengan laptop dan juga dapat mendeteksi cahaya yang disesuaikan Light Meter dengan Sensor Intensitas Cahaya dengan baik.
Perancangan Aplikasi Maturity Meter Menggunakan Implementasi Framework COBIT 5
Authors: Syaifuddin Iqbal Musyaffa , Hermanto Agus
Published: February 2024

Layanan teknologi informasi bukan hanya digunakan sebagai sebuah alat untuk membantu performa dan produktivitas perusahaan atau organisasi, akan tetapi layanan teknologi informasi juga termasuk dalam bisnis strategi yang dimiliki oleh organisasi. Layanan teknologi informasi telah diterapkan di PT.XYZ untuk mendukung kegiatan operasional organisasi, akan tetapi mereka tidak tahu tingkat kematangan pada layanan teknologi informasi yang telah diterapkan yang menyebabkan penurunan tingkat awareness para karyawan terhadap teknologi informasi organisasi. Turunnya tingkat awareness dapat menyebabkan proses operasional organisasi menjadi terganggu. Salah satu framework yang digunakan untuk mengukur tingkat kematangan layanan teknologi informasi adalah framework COBIT. COBIT adalah kerangka panduan tata kelola teknologi informasi yang dapat membantu mengukur tingkat kematangan penerapan teknologi informasi pada organisasi melalui pendefinisian strategi dan kontrol teknologi informasi. Untuk mengurangi kebocoran data yang disebabkan penurunan tingkat awareness para karyawan, maka dibutuhkan sebuah model untuk mengumpulkan data dokumen bukti dan menghitung tingkat kematangan teknologi informasi dengan cepat dan tepat berbasis web dengan metode prototype dan pengumpulan data secara kualitatif untuk menentukan kebutuhan perancangan dan pengukuran tingkat kematangan teknologi informasi organisasi. Perancangan aplikasi ini dapat menampilkan hasil tingkat kematangan sesuai dengan proses framework COBIT dalam bentuk chart.
Penerapan Desain Pattern Observer Pada Pengembangan Aplikasi Android (Studi Kasus: Aplikasi KataFilm)
Authors: Hadisyah Ramadhani Ilham , Suharso Wildan , Rizki Didih
Published: February 2024

Aplikasi seluler sangat mempengaruhi hampir di semua bidang terpenting di kehidupan seperti perbankan, kesehatan, militer dan masih banyak lagi. Dengan hadirnya aplikasi-aplikasi tersebut membawa pengaruh besar di era digital ini terutama perubahan pada masyarakat, baik budaya, etika dan norma yang ada. Dengan keadaan tersebut, banyak perusahaan IT yang dituntut untuk mengembangkan aplikasi seluler dengan cepat, namun mengesampingkan kualitas kode yang menyebabkan meningkatnya kompleksitas kode dan menurunkan nilai metrix maintainability-nya. Salah satu cara untuk menangani permasalahan yang diuraikan diatas adalah penggunaan pola desain yang tepat, salah satunya adalah pola desain observer. Tujuan penelitian ini adalah mengimplementasikan pola desain observer pada aplikasi KataFilm yang sebelumnya memiliki desain pattern Chain of Responsibility yang dianggap memiliki kekurangan khususnya pada sisi maintainabilitynya.
Perancangan UI/UX Fitur Kebugaran Lansia Untuk Membangun Desain Aplikasi Konsultasi Kesehatan Lansia Menggunakan UX Journey
Authors: Muzaki Rizqi Wildan
Published: February 2024

Aplikasi kesehatan lansia adalah solusi teknologi yang dirancang khusus untuk memenuhi kebutuhan kesehatan dan kesejahteraan lansia. Tujuan dari aplikasi ini adalah untuk meningkatkan kualitas hidup para lansia dengan memberikan akses mudah dan terjangkau ke informasi kesehatan, monitoring kondisi fisik dan mental, serta memfasilitasi koordinasi perawatan dengan tim kesehatan. Dengan teknologi yang terus berkembang, aplikasi kesehatan lansia memiliki potensi besar untuk meningkatkan kualitas hidup para lansia dan mengurangi beban sistem perawatan kesehatan. Namun, perlu diperhatikan bahwa penggunaan aplikasi ini harus didukung oleh pendidikan dan pelatihan yang memadai untuk memastikan bahwa lansia dan orang-orang di sekitarnya dapat memanfaatkannya secara efektif dan aman.
Efeitos adversos decorrentes do uso indiscriminado de zolpidem
Authors: Cavalcante Beatriz Gonçalves Urbano , Coelho Guilherme Cabral de Alencar , Moreira Rafael Soares Sales , Bachur Tatiana Paschoalette Rodrigues
Published: February 2024

Zolpidem é um medicamento da classe das imidazopiridinas utilizado no tratamento da insônia, agindo por meio da modulação da função dos receptores GABA. Os distúrbios do sono, marcados pela dificuldade em adormecer, manter a continuidade do sono ou acordar muito cedo pela manhã antes do horário desejado, constantemente prejudicam o cotidiano de grande parte da população mundial, devido a diminuição da produtividade, fato que contribui para o recorrente uso indiscriminado de agentes hipnóticos, a exemplo do zolpidem. Desse modo, o objetivo do presente estudo foi revisar a literatura científica a fim de analisar os principais efeitos adversos decorrentes do uso de zolpidem. Para tal, foi conduzida uma pesquisa bibliográfica nas bases de dados MEDLINE, LILACS e EMBASE. Após a seleção de estudos publicados entre 2017 e 2023, foram incluídos oito artigos na presente revisão. Os resultados dos trabalhos analisados indicam que o uso do zolpidem é bastante eficaz para o tratamento dos distúrbios do sono, mas o seu uso indevido pode trazer reações adversas que são toleradas por alguns indivíduos, como também, pode desencadear danos irreversíveis aos usuários, principalmente, idosos. Portanto, a administração desse medicamento exige uma conscientização dos seus usuários para seguir as orientações posológicas, e requer cautela dos médicos prescritores.
O uso de dietilamida do ácido lisérgico (LSD) e outras drogas psicodélicas no tratamento de transtornos psiquiátricos
Authors: Rattacaso Gabriela Gadelha , Moraes Raíssa Almeida de , Bachur Tatiana Paschoalette Rodrigues
Published: February 2024

Drogas psicodélicas, a exemplo da dietilamida do ácido lisérgico (LSD), são substâncias psicoativas usadas em diversos contextos socioculturais e que, nas últimas décadas, têm ganhado atenção especial quanto a possibilidade de seu uso no tratamento psiquiátrico de alguns transtornos mentais. Neste contexto, o objetivo do presente estudo foi revisar a literatura científica a fim de elucidar os mecanismos neurobiológicos de atuação das drogas psicoativas e discutir sua possível utilização como terapêutica psiquiátrica. Para tal, foi conduzida uma pesquisa bibliográfica nas bases de dados MEDLINE, LILACS e Embase. Após seleção dos estudos publicados entre 2017 e 2023, foram incluídos cinco artigos na presente revisão. Os resultados dos trabalhos analisados indicam envolvimento de drogas psicodélicas na liberação de serotonina e noradrenalina sem efeito tóxico no cérebro. Além disso, os estudos analisados que avaliaram a eficácia e segurança do uso de LSD e outros psicodélicos mostraram resultados promissores, com melhora da qualidade de vida e dos sintomas disruptivos, além de terem sido observados poucos efeitos colaterais. Entretanto, as amostras analisadas ainda são pequenas e, alguns aspectos, como dose a ser utilizada e tempo de tratamento, ainda não foram bem elucidados. Portanto, o uso de psicoativas aponta como uma proposta terapêutica viável em alguns transtornos mentais, porém precisa ser melhor investigada, com a análise de mais variáveis e com o aumento das amostras utilizadas.
THE CONCEPTION OF PEOPLE'S SOVEREIGNTY IN INDONESIA: MOHAMMAD HATTA'S THOUGHT APPROACH
Authors: Eza Aulia  , Isra Saldi , Yuslim
Published: February 2024

Sovereignty of the people is a principle embedded in paragraph IV of the preamble to the opening of the 1945 Constitution. However, the concept of popular sovereignty developed in Indonesia is a different concept from that developed in the West according to Rousseau's teachings. This research is doctrinal legal research using a historical approach and a conceptual approach, namely the idea of people's sovereignty based on Hatta's thoughts as one of the founding figures of the nation. Where the results of the research illustrate that the concept of popular sovereignty developed in Indonesia must be rooted in indigenous Indonesian cultures that have a collectivist pattern, collectivism is here seen as a way to accommodate the diversity of people in Indonesia who are bound by their respective regional characteristics. Conceptually, the people's sovereignty adopted by the Indonesian state contains 5 principles which are grouped into 2 basic principles, namely the essential principle which contains the principle of freedom and the principle of equality, as well as the procedural principle of implementing people's sovereignty which includes the principle of majority vote, the principle of accountability, and the principle of territoriality. The territorial principle is a finding developed from one of the ideals of popular sovereignty for Hatta, namely eliminating cultural nationalism, so that democracy can develop in a button-up manner that accommodates the noble values that exist in Indonesian society.
THE ROLE OF RELIGIOUS FATWAS IN INDONESIA: AN ANALYSIS OF SELF-GOVERNMENT AND BIOPOLITICS DURING THE PANDEMIC
Authors: Fathorrahman  , Prihantoro Hijrian Angga , Fadlullah Nyak
Published: February 2024

This study aims to analyze the role of religious fatwas issued by Indonesian Ulama Council (MUI), Nahdlatul Ulama (NU), and Muhammadiyah in assisting the Indonesian government in implementing health protocols and vaccination programs during the pandemic era. In fact, not all Indonesian citizens comply with the health protocols and vaccination programs established by the Indonesian government. This study employs the concepts of self-government and biopolitics from Michel Foucault's perspective. Both concepts are used to see how MUI, NU, and Muhammadiyah fatwas can control and direct the religious understanding of Indonesian society during the pandemic era. The religious fatwas issued by MUI, NU, and Muhammadiyah play a crucial role in assisting the government in responding to and addressing the contestation of religious discourse during the pandemic era in Indonesia. These three institutions are aware that religious discourse during the pandemic era must consider medical discourse. With religious narratives considered inclusive and adaptive to the issues faced by Indonesian society during the COVID-19 pandemic, fatwas from MUI, NU, and Muhammadiyah can shape and guide the religious awareness of Indonesian society in the public sphere. This research concludes that religious fatwas, especially in the pandemic era, are capable of positioning religious discourse and scientific knowledge proportionally
FLAGELLATION IMPOSED AS A SANCTION BASED ON THE ASPECT OF CHILD PROTECTION
Authors: Nurini Aprilianda  , Mufatikhatul Farikhah  , Liza Agnesia Krisna
Published: February 2024

Aceh came up with a sharia-based compilation of penal law, Qanun Number 6 of 2014 concerning Jinayat Law. QanunJinayat governs the provisions regarding a child involved in jarimah, where several principles set forth in the regulatory provisions differ from those in the national judicial system of juvenile crime. This study discusses the differences in the handling of the violation of Qanun Jinayat by children on which flagellation is imposed in terms of the aspect of child protection. This study was conducted based on socio-legal and socio-juridical approaches. The research result shows that flagellation imposed on a child contravenes the child protection principle in the national judicial system of juvenile crime. The flagellation regulated in Qanun Jinayat is based on the consideration suggesting that flagellation is the essence of punishment in Islamic law. Qanun Jinayat should be evaluated by referring to the principle of child protection in the national judicial system to reach the objectives of legal protection in children especially those facing legal disputes.
Competency Development in Industrial Engineering and Related Academic Programs Regarding the Optimization of Production and Logistics Processes: The Case of Medellín
Authors: Aguirre-Álvarez Yenny Alejandra , Montoya-Peláez Mauricio , Trujillo-Cabezas Raúl , Solano Hurtado Camilo Esteban
Published: February 2024

This study examines the correlation between the skills and competencies developed in engineering programs and those required by the most representative economic sectors in Medellín for optimizing their production and logistics processes. In general terms, this paper aims to contribute to the research on higher education institutions and the alignment of their programs with the expectations of businesses in emerging countries. Thus, the proposed research question is as follows: What is the systemic relationship between academia and businesses in Colombia regarding the development of skills and competencies related to the optimization of production and logistics processes? To address this question, the study methodology starts by defining the target population (Industrial Engineering and related academic programs) and the dialogue methods adopted. Subsequently, a morphological space is created to establish systemic interconnections among the study variables and factors. Finally, patterns and qualitative/quantitative relationships are identified and grouped into two drivers that support the optimization of production and logistics processes. These drivers, in turn, consist of five key driving variables: quality defects, work environment, information and communication technology usage, operation traceability, and logistics and planning. The results indicate a correlation of 60% between courses and job competencies, 85.71% between academic skills and job competencies, and 71.88% between courses and academic skills. These findings provide insights to enhance cooperation between the academic and business sectors and foster the development of new local competitive capacities.