bluuebunny/crossref_metadata_2025 huggingface dataset:
A Cross-Sectional Study of Etiological and Sensitivity Profiling of Meningitis in Under-Five Children
Authors: Gahlot Tanushree , Kasana Dimple
Published: September 2024

Objectives:

The study aimed to understand the organism spectrum and antibiotic sensitivity profile of acute bacterial meningitis in pediatric population.

Methods:

A cross-sectional study was conducted at the department of microbiology of a tertiary care center for a period of 18 months. Suspected cases of meningitis between 1 and 60 months of age were considered for the study. All cases underwent cerebrospinal fluid tap for direct microscopy (DM), Gram staining, and culture sensitivity.

Results:

The mean age of the study patients was 10.42 months, with 61.7% of males and 38.3% of females. DM and culture were positive in 22.90% and 28.00% of the patients, respectively. On Gram stain, there were 29 (59.18%) cases of Gram positivity and 20 (40.82%) cases of Gram negativity. The culture growth showed that Acinetobacter spp. was isolated in 15 (30.6%) of the cases. Enterococcus spp. was isolated in 9 (18.4%) of the cases. Klebsiella pneumoniae was isolated in 8 (16.3%) of the cases. Staphylococcus aureus was isolated in 8 (16.3%) of the cases. Enterobacter spp. was isolated in 3 (6.12%) of the cases. Pseudomonas aeruginosa was isolated in 3 (6.12%) of the cases. Streptococcus pneumoniae was isolated in 3 (6.1%) of the cases. The antibiogram of different agents showed wide variation, with colistin being 100% sensitive for Acinetobacter, Enterobacter, K. pneumoniae, and P. aeruginosa.

Conclusion:

The present study revealed that Acinetobacter, Enterococcus, K. pneumoniae, and S. aureus were the most common bacterial etiologic agents of ABM. The 100% antibiotic sensitivity of the organisms to some antibiotics may suggest the use of such antibiotics while awaiting for culture sensitivity reports.
Rare Manifestation of Ocular Immune Reconstitution Inflammatory Syndrome from Mycobacterium Scrofulaceum Infection in a Patient with AIDS
Authors: Jiamjunkupt Thanin , Sasiprapha Nathamon , Changpradub Dhitiwat , Choontanom Raveewan , Sansanayudh Wiwan
Published: September 2024

Immune reconstitution inflammatory syndrome (IRIS) is a common complication following the initiation of antiretroviral therapy (ART). The most commonly associated pathogens include Mycobacterium tuberculosis and Cryptococcus spp.[1] IRIS following nontuberculosis mycobacteria (NTM) infection is uncommon, particularly, IRIS following NTM conjunctivitis.[2] Herein, we present a case of Mycobacterium scrofulaceum conjunctivitis with peripheral ulcerative keratitis and orbital cellulitis in a 45-year-old patient with AIDS who developed IRIS 1 month after starting ART therapy. A combination of both systemic and topical antibiotics together with corticosteroids were used and resulted in a satisfactory outcome with no early recurrence. This case demonstrated a rare ocular IRIS manifestation involving both the external eye and orbit and to the author's knowledge is the first case in the literature in which M. scrofulaceum has been found to be involved in the eye.
A Laboratory-Based Analysis of Rapidly Growing Mycobacteria in Northwest Paulista, Sao Paulo, Brazil
Authors: da Silveira Paro Pedro Heloisa , Tonelli Nardi Susilene Maria , Ule Belotti Naiara Cristina , Tegon de Freitas Ana Carolina , de Souza Nilza Gomes , Chimara Erica
Published: September 2024

Background:

Rapidly growing mycobacteria (RGM) are a group of nontuberculous mycobacteria (NTM) implicated in difficult-to-treat pulmonary and extrapulmonary diseases, possibly associated with invasive procedures and failures in sterilization of materials and equipment.

Methods:

We report our experience with the laboratory identification of RGM in a routine work and give an overview of the RGM isolated in our setting. Laboratorial data from all RGM mycobacterial isolates received at Adolfo Lutz Institute of São José do Rio Preto were analyzed from January 2000 to December 2015.

Results:

Five hundred and seventy-nine isolates were identified with NTM, of which 193 were RGM, which affected 113 patients. Among the 113 patients, the female gender was more frequent (55%) and the average age was 50 years. Pulmonary samples were the most frequent (79%), and 54.9% of the cases were isolated from sputum. Twelve different species were found and the most identified were group Mycobacterium abscessus and Mycobacterium fortuitum, making up 77.9% of all identified RGM. The most frequent comorbidities were smoking (n = 21), alcoholism (n = 12), and human immunodeficiency virus (n = 16). Drug susceptibility test was performed for nine patients and all showed susceptibility to amikacin and seven resistances to doxycycline.

Conclusions:

This study showed the experience of mycobacterial diagnosis in a routine laboratory, revealing that failure to meet the bacteriological criteria generates losses in the establishment of cases of RGM and consequently its correct treatment.
Bacillus Calmette-Guerin as a Quick and Temporary Solution to Coronavirus Disease-2019
Authors: Kumari Priyanka , Gupta Umesh Datta , Bhagyawant Sameer Suresh
Published: September 2024

The coronavirus disease-2019 (COVID-19) pandemic is one of the most devastating things that happened in the world which has taken the lives of millions of people and has brutally shattered the world economy. This pandemic has instigated an urgent need for a vaccine to reduce the ongoing morbidity and mortality. Bacillus Calmette-Guerin (BCG) apart from being used as an effective and old vaccine against tuberculosis has some known off-target protection effect and is getting more attention in this scenario. BCG confers nonspecific innate immune-boosting effects called trained immunity against secondary infection. Various recent publications have proposed the inverse relationship between the COVID-19 morbidity and mortality with that of BCG coverage of that country on the basis of epidemiological studies. However, these studies have not considered the confounding factors, and a lot of recent articles are contradicting these epidemiological and observational data. Several random control trials for BCG on health-care workers and elderly people are ongoing worldwide and could depict the actual relation between COVID-19 and BCG protection. Although a recent trial has found a protective function of BCG against COVID-19 in health-care workers, more results of the trials can only give approval on this. There has been a shortage of BCG worldwide due to its use in bladder cancer and vaccination in neonates, and hence, its use should be carefully regulated. In this review, we have tried to summarize the various issue and conflicts on BCG to be used as a temporary solution to COVID-19.
Impact and Cost-Effectiveness Evaluation of Nutritional Supplementation and Complementary Interventions for Tuberculosis Treatment Outcomes under Mukti Pay-for-Performance Model in Madhya Pradesh, India: A Study Protocol
Authors: Prinja Shankar , Sharma Atul , Nadipally Sudheer , Rana Saroj Kumar , Bahuguna Pankaj , Rao Neeta , Chakraborty Gautam , Shankar Manjunath , Rai Varsha
Published: September 2024

Background:

A ”pay-for-performance” (P4P) intervention model for improved tuberculosis (TB) outcomes, called “Mukti,” has been implemented in an underdeveloped tribal area of central India. The target of this project is to improve nutritional status, quality of life (QoL), and treatment outcomes of 1000 TB patients through four interventions: food baskets, personal counseling, peer-to-peer learning and facilitation for linkage to government schemes. The current study aims to assess the success of this model by evaluating its impact and cost-effectiveness using a quasi-experimental approach.

Methods:

Data for impact assessment have been collected from 1000 intervention and control patients. Study outcomes such as treatment completion, sputum negativity, weight gain, and health-related QoL will be compared between matched samples. Micro costing approach will be used for assessing the cost of routine TB services provision under the national program and the incremental cost of implementing our interventions. A decision and Markov hybrid model will estimate long-term costs and health outcomes associated with the use of study interventions. Measures of health outcomes will be mortality, morbidity, and disability. Cost-effectiveness will be assessed in terms of incremental cost per quality-adjusted life-years gained and cost per unit increase in patient weight in intervention versus control groups.

Results:

The evidence generated from the present study in terms of impact and cost-effectiveness estimates will thus help to identify not only the effectiveness of these interventions but also the optimal mode of financing such measures. Our estimates on scale-up costs for these interventions will also help the state and the national government to consider scale-up of such interventions in the entire state or country.

Discussion:

The study will generate important evidence on the impact of nutritional supplementation and other complementary interventions for TB treatment outcomes delivered through P4P financing models and on the cost of scaling up these to the state and national level in India.
Primary tumor lymphangiogenesis in oral squamous cell carcinoma with N0 neck is the key determinant of its therapeutics
Authors: Tandon Ankita , Sandhya Kumari , Singh Narendra N. , Kumar Amit
Published: September 2024

Background:

Vascular Endothelial Growth Factor-C (VEGF-C) plays a critical role in tumor growth and invasion through lymphangiogenesis and helps to identify the variability of lymphatic potential of oral squamous cell carcinoma (OSCC) cases with or without lymph node metastasis.

Materials and Methods:

A total of 65 cases of OSCC were included. The clinical details were obtained from patient records. The cases were grouped as N0 versus any N categories. All the cases were immunohistochemically evaluated for VEGF-C within the primary tumor using a standard protocol. An average of 5 lymph nodes were dissected from all neck dissection specimens and were evaluated histopathologically. The data obtained were statistically evaluated at 95% confidence interval and P ≤ 0.05.

Results:

100% cases in our study showed VEGF-C immunopositivity. The immunoreactivity increased linearly with advancing grades. A total of 31 out of 40 N0 OSCC revealed score 2 (26%–50%) of VEGF-C immunoreactivity. Eighteen cases were false negative clinically.

Conclusion:

Recognition of locoregional spread may empower clinicians for correct therapeutic decisions in N0 versus any N case.
Clot waveform analysis of prolonged activated partial thromboplastin time in various disorders
Authors: Kadu Apeksha , Shah Ami M. , Goswami Hansa
Published: September 2024

Introduction:

The prolongation in APTT reflects various disorders affecting the blood coagulation system. Automated coagulation analyzers such as ACL TOP, help in evaluating the clotting cascade by displaying clot reaction curves or waveforms. The fibrin formation curve forms S-shaped curve showing the changes in the absorbance on X-axis and time in seconds on Y-axis. The clotting data is processed to obtain derivatives.

Materials and Methods:

This observational study analyzed 80 samples including 20 samples from normal healthy individuals as control. The parameters studied were time (secs), height (mAbs), and width (secs) of first derivative (FD), fibrin clot time at ½ height, height (mAbs), and width (secs) of both first and second peaks of second derivative (SD).

Result and Discussion:

Hemophilia (n = 13) that consisted of factor VIII deficiency (n = 11) and factor IX deficiency (n = 2) showed biphasic patterns in both first DC and second DC. Cases with thrombosis (n = 8) showed marked elevation in first DC. Various other disorders (n = 39) that consisted of mainly hepatic dysfunction (n = 24) showed prolongation in fibrin formation, first DC, and second DC peak time.

Conclusion:

The atypical derivative curve analysis helps in determining the interferences in clotting cascade. It gives significant information and provides direction for further testing.
Advanced female urethral adenocarcinoma: A case report
Authors: Sharma Ankitkumar , Kumar P. B. Barani , Muthusamy Rajeshwari K. , Mehta Sangita S.
Published: September 2024

Urethral cancer in females is a rare occurrence. Although initially believed to be derived from skene glands, there is no consensus on the cell of origin. Squamous cell carcinoma is the most common, whereas adenocarcinoma is the least common. We report the case of a 58-years-old lady with a history of voiding lower urinary tract symptoms, later requiring a suprapubic cystostomy for retention. Cystoscopy and biopsy showed prostate-specific antigen (PSA) negative adenocarcinoma and postiron emission computed tomography (PETCT) showing pelvic and inguinal nodal metastasis. The patient underwent neoadjuvant chemotherapy followed by anterior exenteration with pelvic lymphadenectomy and ileal conduit. Final histology showed ypT4 yN1 adenocarcinoma, not otherwise specified.
Expeditious management of an unexpected complication of left renal vein ligation during right retroperitoneoscopic simple nephrectomy: A lesson learned the hard way
Authors: Bhargava Priyank , Sharma Kartik , Singh Mahendra
Published: September 2024

We present a case of inadvertent left renal vein clipping during right retroperitoneoscopic nephrectomy (RPN) and describe its expeditious identification and management. A 13-year-old girl underwent RPN for nonfunctioning kidney due to urolithiasis. During the dissection of the right renal vein, the inferior vena cava (IVC) got lifted off the parietal wall and the left renal vein was mistakenly ligated. Based on a strong intra-operative suspicion, the patient underwent an urgent computed tomography angiography which confirmed the ligation of the left renal vein. The patient was reoperated immediately and an end-to-side anastomosis was performed between the left renal vein and the IVC.
An effective Ayurveda management of Sarvangavata W.S.R. to Guillain–Barre syndrome: A case report
Authors: Aswathy Y. S. , Therokar Sagar , Dahiya Abhijeet , Dharmarajan Prasanth
Published: September 2024

Guillain–Barré syndrome (GBS) is a rare but potentially serious autoimmune disorder affecting the peripheral nervous system, leading to muscle weakness, paralysis, and in severe cases, respiratory failure. Therapies, such as immunoglobulin therapy and plasmapheresis, are considered mainstays of GBS treatment. Ayurveda treatment can potentially offer therapeutic support to GBS patients in enhancing recovery. A 43-year-old male presented to the in-patient department of an Ayurvedic hospital with bilateral weakness in both upper and lower limbs, accompanied by pain in the left thigh and lower back region, as well as tingling sensations in the ring and middle fingers of the right hand. Following a comprehensive evaluation, including clinical assessment, neurological examination, magnetic resonance imaging, and nerve conduction study, a conclusive diagnosis of GBS was established. Based on the detailed Ayurveda assessment, an Ayurveda diagnosis of Sarvangavata was also made. Upon admission, the patient underwent a comprehensive in-patient treatment regimen spanning 44 days, which included Udwarthana (dry powder massage), Ksharavasti (enema), Sneha Pana (internal administration of medicated oils), Abhyanga (oil massage) and Sweda (sudation therapy), Virechana (therapeutic purgation), Samsarjana Karma (diet for restoring Agni)), Vasti (medicated enema), Shirobasti (medicated oil retention in the head), Pizhichil (oil bath therapy), and Nasya (nasal administration of medicine). Following these intensive therapies, the patient was discharged and continued on Samana Ousadha (palliative medication) for ongoing management of symptoms. The patient was routinely followed up for 6 months with routine clinical assessments and the symptoms gradually improved and consistent recovery was noticed. This case study underscores the promising prospects of integrating Ayurvedic principles and treatments into the management of GBS. However, to substantiate these findings and elucidate the mechanisms through which Ayurvedic therapies operate, further investigation and rigorous clinical trials are warranted.
Ayurveda Approach in the Management of Hypertensive Retinal Hemorrhage: A Case Report
Authors: Prabi Kunneparambil Prakasan , Garg Vandna , Mehar Kapil , Tripathi Ankur , Bavalatti Narayan , Rajagopala Manjusha
Published: September 2024

Hypertensive retinopathy (HR) refers to changes in the retinal microvasculature that occur with elevated blood pressure and are a visible manifestation of vascular damage. A 54-year-old female patient presented with complaints of headache and blurred vision in both eyes over the last year and with a 5-year history of hypertension. On fundus examination, a flame-shaped hemorrhage associated with arteriolar light reflex changes (copper wiring) was observed in the inferior quadrant of the right eye with deflection of veins at the arteriovenous crossing (Salu’s sign). Management was done on an outpatient basis for 1 month, which included oral administration of Avipattikara Churna, Kaishora Guggulu, Brihat Manjishtadi Kwatha, and Saptamrita Lauha. The retinal features of HR underwent complete resolution with the Ayurveda treatment regimen for 26 days. HR-induced retinal hemorrhage can be successfully managed with the Ayurveda treatment approach.
An Exploratory Case–Control Study for Mitochondrial DNA G10398A in Bipolar I Disorder Patients with a Family History of Affective Disorders
Authors: Mishra Rajan , Quraishi Rizwana , Deep Raman , Jain Raka
Published: September 2024

Background:

The mitochondrial DNA (mtDNA) G10398A polymorphism has been associated with bipolar disorder (BD). It leads to an amino acid substitution within NADH dehydrogenase subunit, thereby altering the mitochondrial complex I function. This exploratory case–control study assesses the association of mtDNA G10398A with the risk of BD and its relationship to clinical variables in Indian patients.

Methods:

Cases met the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition diagnosis of BD-I in remission and had a family history of BD or recurrent unipolar disorder in biological relatives. The healthy controls (HC) had no known illness and were screened negative for Family Interview for Genetic Studies. Participants were assessed using Clinical Pro forma, NIMH-Life Chart Method and Alda lithium response scale. The mtDNA G10398A was assessed with real-time polymerase chain reaction using TaqMan assay.

Results:

A total of 82 participants were recruited across cases and controls, with 42 patients (50% with maternal history) and 40 healthy individuals with similar demographic profiles. The mean age of onset was 25.16 (standard deviation [SD] 7.6) years, with illness for 11.59 years (SD: 7.18). Allele A was found in 50% of cases compared to 32.5% HC (odds ratio = 2.08; 95% confidence interval [CI]: 0.85–5.09). Findings remain non-significant for patients with maternal mood disorders (allele A: 38.9%; 21/42). Cases with allele G had significantly higher body mass index (BMI) (P = 0.008) than those with allele A.

Conclusion:

The study adds information on mtDNA 10398A amongst Indian patient samples and healthy individuals. No significant group difference was found with respect to mtDNA G10398A. The positive association of allele G with higher BMI has potential clinical relevance that can be further investigated in larger samples.
Obesity and the Need for Bariatric Surgery in Nigeria: A Review
Authors: Adenuga Adedire Timilehin , Salu Iliya Karniliyus , Bello Usman Mohammed , Okaro Abuchi
Published: September 2024

Obesity was mainly regarded as a disease of developed countries, but currently there is a growing rise in the population of patients with obesity in developing countries of Africa. A body mass index of 30 kg/m2 or higher is regarded as obesity, and this may be associated with comorbidities such as metabolic and cardiovascular diseases, orthopaedic and psychiatric conditions, and cancer. There is conclusive scientific evidence that shows that obesity is caused by complex psychosocial, genetic and environmental factors. Diet and exercise are not effective as sole management of severe obesity. Bariatric surgery is the most cost-effective definitive treatment for all classes of obesity, and the associated weight reduction causes improvement or complete resolution of obesity-associated comorbidity, improves the quality of life and reduces all-cause mortality. It is estimated that about 15% of adults in Nigeria are obese, and in the year 2023, it was reported that only 214 bariatric procedures were done locally, with 134 (62.6%) being gastric balloon insertions, 75 (35.1%) primary weight loss surgeries and 5 revisional surgeries (2.3%). In this article, we discussed the existing weight loss options in Nigeria, the current state of bariatric surgery and the need to improve the practice of bariatric surgery for obese Nigerians and complications of obesity.
Prevalence, Characteristics and Distribution of Odontogenic Cysts amongst the Indian Subpopulation of Southern Rajasthan: A 5-year Retrospective Study of 218 Cysts
Authors: Khandelwal Pulkit , Rai A. Bhagavandas , Bulgannawar Bipin , Gupta Himanshu , Khan Zibran , Hajira Neha
Published: September 2024

Background:

Odontogenic cysts (OCs) arise from the odontogenic epithelium and occur in the tooth-bearing regions of the jaws. Proliferation and/or degeneration of this epithelium lead to OC development.

Aim and Objectives:

The purpose of this study was to determine the prevalence, characteristics, distribution and clinicopathological features of OCs and compare with other studies.

Materials and Methods:

Records of OCs were retrieved, and patient’s data, aetiology, clinical features, histopathological distribution, treatment, complications and recurrence were studied.

Results:

A total of 218 OCs were studied in 200 patients. The mean age of patients was 35.74 years. The overall sex ratio (male: female) was 1.22:1. Second, third and fourth decades of life were commonly affected. The majority of the patients (85%) reported with a complaint of pain (with or without swelling). Radicular cyst was the most prevalent type (49.55%). The most common site involved was the anterior maxilla (41.75%). Dental complications such as displacement, mobility, discoloration and root resorption were diagnosed in 91 cysts (41.75%). Bony complications such as expansion and perforation were present in 136 cysts (62.38%). Dentition was non-vital in 61.46% of cysts. The most common treatment method performed was combination surgery (enucleation with or without endodontic treatment/extraction and apicoectomy). Recurrence rate was 3.20%.

Conclusion:

The prevalence, characteristics and distribution features of OCs in India are similar to those of studies conducted in other parts of the world. There is a broad spectrum of OCs, with some cysts having a propensity for certain age, gender and site, whereas a few cysts have distinct properties to recur and have aggressive and invasive behaviour.
Prevalence of Hypertension, Its Risk Factors and 10-year Cardiovascular Disease Risk among Bank Employees in Lagos State, Nigeria
Authors: Ojo Omobola Yetunde , Olasehinde Tolulope , Adeniran Adeyinka , Chieme Chisom Florence , Aderibigbe Adedayo Ayodele
Published: September 2024

Background:

Hypertension is a significant global public health concern, with unique risk factors affecting those in the banking sector due to their work environment. This study aimed to determine the prevalence of hypertension among bank employees and identify specific contributing risk factors.

Materials and Methods:

A cross-sectional survey of 250 bank employees used pretested structured questionnaires. Various measurements, including body mass index (BMI), blood pressure, lipid profile parameters and cardiovascular events, were recorded. Data were analysed using SPSS software. Categorical variables are presented as frequencies and percentages. Binary logistic regression was employed to identify independent predictors of hypertension (P < 0.05).

Results:

The study participants had a mean age of 37.56 ± 8.98, with 54.5% being female. The majority (98.8%) had tertiary education, and 94.7% resided in urban areas. The prevalence of hypertension was 33.3%. Higher BMI is significantly associated with increased odds of hypertension. For each unit increase in BMI, the odds of having hypertension are approximately 1.98 times higher. Hypertension was also significantly more prevalent in those participants with prior hypertension diagnosis, those with a family history of hypertension, smokers and those who added salt to their food on the table (P < 0.05).

Conclusion:

The alarmingly high prevalence of hypertension underscores the need for targeted intervention and health promotion initiatives. With recognised risk factors, emphasis must be placed on the importance of lifestyle modifications and workplace wellness programmes to mitigate the burden of hypertension.
An extension of the Fukaya–Kato method
Authors: Sharifi Romyar
Published: September 2024

In a groundbreaking paper, T. Fukaya and K. Kato proved a slight weakening of a conjecture of the author under an assumption that a Kubota–Leopoldt

p

-adic

L

-function has no multiple zeros. This article describes a refinement of their method that sheds light on the role of the

p

-adic

L

-function.
Hindi translation and validation of the English version of the gastrointestinal symptom rating scale questionnaire: An observational study
Authors: Jindal Neha , Jena Anuraag , Kumar Krishan , Padhi Bijaya K , Sharma Rajni , Jearth Vaneet , Dutta Usha , Sharma Vishal
Published: September 2024

BACKGROUND

The gastrointestinal symptom rating scale (GSRS) is a questionnaire in English language which is designed to assess the clinical symptoms in patients with irritable bowel syndrome (IBS) and peptic ulcer disease. This validated scale has questions on around 15 items and has been validated in patients with dyspepsia and IBS.

AIM

To translate and validate the English version of the GSRS questionnaire to the Hindi version.

METHODS

The purpose of the present work was to create a Hindi version of this questionnaire for use in the Indian population. The process involved various steps as per the World Health Organization methodology including initial forward translation, backward translation, and assessment by an expert committee. Initial pilot testing was followed by testing in healthy and diseased individuals.

RESULTS

The Hindi translation was pilot tested in 20 individuals and further validated in healthy controls (n = 30, 15 females) and diseased individuals (n = 72, 27 females). The diseased group included patients with functional dyspepsia and IBS. Cronbach's alpha for internal consistency on the final translated GSRS questionnaire was 0.715 which is considered adequate. Twelve questions significantly differentiated the diseased population from the healthy population (P value < 0.05) in the translated Hindi version of the GSRS.

CONCLUSION

The translated Hindi GSRS can be used to evaluate gastrointestinal function in clinical trials and community surveys in Hindi speaking populations.
“Marvellous Scripture of the Divine Incantations of the Emperor of the North” Through the Lens of Social Crisis
Authors: Petrovčič Živa
Published: September 2024

This article explores the Daoist scripture titled Dongzhen taiji beidi ziwei shenzhou miaojing 洞真太極北帝紫微神呪妙經 (Marvellous Scripture of the Divine Incantations of the Deity of the Pole Star, Emperor of the North of the Supreme Ultimate, A Dongzhen Canon), which was arguably composed during the Eastern Jin dynasty in Southeast China. The examination aims to illuminate portrayals of crisis and the presented solutions, and thus investigate reflections of and responses to the social crisis of the period. The study demonstrates how the messaging about the crisis is structured and how individual aspects inter-relate, while simultaneously exploring its correlations with historical circumstances, thus also revealing information on the movement from which the scripture originated, i.e. the author and the intended audience. In doing so, it shows how the author creates a proselytizing strategy which is particularly tailored to the audience in the social crisis of the time. The purpose of this study is also to highlight the significance of considering crisis-related content or message in the scripture as a whole, including correlations with specific historical circumstances.
Alchimia speranței
Authors: Palaghianu Ciprian , Nichiforel Liviu , Barnoaiea Ionuț
Published: September 2024

Profesor doctor inginer Radu Leontie Cenușă, Profesor Emeritus al Universității Ștefan cel Mare Suceava, creator de școală silvică, decan al Facultății de Silvicultură Suceava și distins cercetător a fost o figură emblematică a silviculturii românești. De o anvergură intelectuală uriașă, profesorul Radu Cenușă a susținut activ ideea de reînființare a școlii silvice superioare în Bucovina unde a fost un dascăl excepțional, cu o abilitate uimitoare de a transmite cunoștințele și de a inspira discipoli. Un proiect caracteristic spiritului optimist al domnului profesor a fost renașterea revistei științifice ”Bucovina Forestiera”. Din 1977 a urcat treptele ierarhice în cadrul colectivului de cercetare al Stațiunii Câmpulung Moldovenesc din cadrul Institutului de Cercetări și Amenajări Silvice, iar din 1993 a activat în cadrul Facultății de Silvicultură Suceava unde a fost decan în perioada 2004-2008. Activitatea sa științifică a fost recunoscută prin numeroase premii naționale și internaționale, precum Premiul ”Leopold Pfeil” al Fundației Freiherr von Stein, Hamburg (1984), Premiul ”Traian Săvulescu” al Academiei Române (1990) sau Premiul ”Progresul Silvic” (1992). A fost un om cu viziune și alchimist al speranței luptând până în ultima clipă pentru idealurile sale morale.
Boğaz Sözcüğünün Monografisi: Boğaz Sözcüğünün Kavram Alanı ve Kullanımı Üzerine Bir İnceleme
Authors: Yaman Hanife
Published: September 2024

Monografik yöntem, ele aldığı unsuru tüm yönleriyle inceler. Özellikle halk bilimi alanında yaygın olarak kullanılan bu yöntem dil araştırmalarında da kullanılmaktadır. Sözcük monografisi adı verilen çalışmalarda, bir dilde incelenmek istenen bir sözcük, art zamanlı ve eş zamanlı olarak ele alınmakta ve sözcüğün dildeki kullanımının tüm yönleriyle ortaya konulması amaçlanmaktadır. Türkçenin temel söz varlığında, organ adlarından biri olan “boğaz” sözcüğü işlek bir yapıya sahiptir. Tanıtımı yapılan eserde, “boğaz” sözcüğünün anahtar kelime olarak seçilmesinde, sözcüğün bu özelliğinin etken olduğu düşünülmektedir. Dr. Şahin Yıldız’a ait bu çalışma, “boğaz” sözcüğü üzerine hazırlanan bir sözcük monografisidir. Metin tarama yöntemiyle hazırlanan bu kitap, üç müstakil bölümden oluşmaktadır. İlk bölüm, “Boğaz Sözcüğü Üzerine Bilgiler” adını taşımaktadır. Bu bölümde, sözcüğün kökeni, yapısı ve anlamıyla ilgili bilgiler ve kullanımlar üzerinde durulmuştur. “Dil ve Edebiyat Ürünlerinde Boğaz” adını taşıyan ikinci bölümde, Türkçenin dil ve edebiyat ürünlerinde boğaz sözcüğünün anlamı ve kullanımı eserlerden tanıklanarak sunulmuştur. “Diğer Bilim Dallarında Boğaz” adlı üçüncü bölümde ise “boğaz” sözcüğünün işlek bir yapıya sahip olduğunu da tanıklayan farklı disiplinlerle olan ilişkisi ortaya konulmuştur. “Boğaz” sözcüğünün Türk dilinin Eski Türkçe döneminden bugüne kazandığı farklı anlam ve kullanım alanlarının ortaya konulduğu bu eser tanıtılarak, Türkoloji alanına yaptığı katkılar üzerinde durulmuştur.
COMPARISON OF FASTING BLOOD GLUCOSE LEVELS (BETWEEN GOD-PAP METHOD AND STRIP METHOD) IN DIABETES MELLITUS PATIENTS ATSOKARAJA PUBLIC HEALTH CARE CENTER 1
Authors: Saputri Ririn Indah
Published: September 2024

ABSTRACT
Diabetes Melitus is a severe chronic disease that occurs when the pancreas does not produce enough insulin (a hormone that regulates blood sugar or glucose), or the boddy cannot effectively use the insulin it produces (WHO, 2016). This was an analytical observasional comparative study to compare the results of fasting blood glucose examination using the GOD-PAP method and the Strip method with a Cross-Sectional study design in patients with Diabetes Melitus at Puskesmas Sokaraja 1. The sample of this study was 56 patients, with the number or patients examined, 28 people. All samples from DM patients has had blood glucose levels more than the normal limit, and the measurement results showed a difference in fasting blood glucose levels with the GOD-PAP method and the Strip method was carried out using the T-Dependent Test, which showed a p-value=0.000 (p<0.05), so it can be concluded that there is a significant comparison of fasting blood glucose levels between the GOD-PAP method and strip method in Diabetes Melitus patients at Sokaraja Health Care Center 1.
Keywords: Fasting blood glucose, GOD-PAP, Strip test
 
ABSTRAK
Diabetes Melitus merupakan penyakit kronis serius yang terjadi karena pankreas tidak menghasilkan cukup insulin (hormon yang mengatur gula darah atau glukosa), atau ketika  tubuh tidak dapat secara efektif  menggunakan  insulin  yang  dihasilkan  (WHO,  2016).  Penelitian  ini  adalah  observasional analitik yang bersifat studi komparatif untuk membandingkan hasil pemeriksaan glukosa darah puasa menggunakan metode GOD-PAP dengan metode strip dengan rancangan penelitian menggunakan Cross Sectional. Tujuan penelitian ini yaitu untuk mengetahui perbandingan hasil pemeriksaan kadar glukosa darah puasa metode GOD-PAP dengan metode strip pada penderita Diabetes Melitus di Puskesmas Sokaraja 1. Sampel penelitian ini berjumlah 56 dengan jumlah yang diperiksa adalah 28 pasien. Seluruh sampel dari pasien DM memiliki kadar glukosa darah lebih dari batas normal dan hasil pengukuran menunjukkan selisih kadar glukosa darah puasa metode GOD-PAP dengan metode strip sebesar 84,75 mg/dL. Penentuan perbandingan kadar glukosa darah puasa metode GOD-PAP dan metode strip dilakukan dengan menggunakan Uji T-Dependent yang menunjukkan nilai p=0.000 (p<0.05),  sehingga  dapat  disimpulkan  bahwa  terdapat  perbandingan  yang  signifikan  pada  kadar glukosa darah puasa metode GOD-PAP dengan metode strip pada pasien Diabetes Melitus di Puskesmas Sokaraja 1.
Kata kunci : Glukosa darah puasa, GOD-PAP, Strip tes
GAMBARAN JUMLAH ERITROSIT PADA PASIEN SUSPEK COVID-19 DI RSUD KOTA KENDARI
Authors: Umar Ani , Wenty Darmayanita , Salni Salni
Published: September 2024

ABSTRACT
Red blood cell or called Erythrocyte is red blood that has the most number of blood cells in the human body. The number of red blood cells can provide information that indicates the presence of hematological disordes. Hematological disorder is interference with the formation of red blood cells, including a decrease and increase in the number of cells (polycythaemia). Reduction in the number of red blood cells is found in chronic diseases, such as: liver disease, anemia, and leukemia, while polycythemia is found in patients with diarrhea, severe dehydration, burns, and heavy bleeding. The purpose of this study was to determine description of erythrocyte amounts in covid-19 suspected patients by using descriptive research, and sampling with total sampling from June -July 2020. The sample of this study was the result of examination of the number of erythrocytes in patients with suspected Covid-19. The results of the study provided a high number of erythrocytes found in patients with suspected Covid-19, as many as 7 patients (26%), the number of erythrocytes in patients with suspected Covid-19 was low, as many as 1 patient (4%), and the normal erythrocytes in patients with suspected Covid-19 was 19 patients (70%).
 
key words: Erythrocyte, Covid-19, Number of Erythrocytes.
 
ABSTRAK
Sel darah merah atau disebut juga eritrosit merupakan sel darah yang jumlahnya terbanyak dalam tubuh manusia.  Jumlah sel darah merah dapat memberikan informasi yang mengindikasikan adanya gangguan sel darah. Gangguan sel darah adalah gangguan pada pembentukan sel darah merah, meliputi penurunan dan peningkatan jumlah sel (polisitemia). Penurunan jumlah sel darah merah ditemukan pada penyakit kronis, seperti penyakit hati, anemia, dan leukemia, sedangkan polisitemia ditemukan pada penderita diare, dehidrasi berat, luka bakar, maupun pendarahan berat. Tujuan penelitian ini untuk mengetahui gambaran jumlah eritrosit pada pasien suspek Covid-19. Jenis penelitian ini adalah deskriptif dan pengambilan sampel dilakukan dengan total sampling yang merupakan data suspek Covid-19 di RSUD Kota kendari pada bulan juni-juli 2020. Sampel penelitian ini adalah data hasil pemeriksaan jumlah eritrosit pasien suspek Covid-19. Hasil penelitian menunjukkan jumlah eritrosit yang tinggi dijumpai pada pasien suspek Covid-19 yaitu 7 pasien (26%), jumlah eritrosit pada pasien suspek Covid-19 yang rendah yaitu 1 pasien (4%), dan jumlah eritrosit yang  normal pada pasien suspek Covid-19 yaitu 19 pasien (70%).
Kata Kunci : Eritrosit, Covid-19, Jumlah Eritrosit.
Microbial Fuel Cell: Optimizing Graphene-Sponge Anode Thickness and Chamber pH Using Taguchi Experimental Method
Authors: Navarro Emilio Steven C. , Boado Melissa May M.
Published: September 2024

The rapid consumption of fossil fuels has led to calls to switch from non-renewable to renewable energy sources. Microbial fuel cells are a promising technology that simultaneously treats wastewater and produces power. This study used the Taguchi Experimental method to optimize anode thickness and pH to obtain the maximum power density of an air-cathode microbial fuel cell (ACMFC). The graphene-sponge (G-S) anode thickness and chamber pH were selected as operating parameters, with their corresponding levels. The L9 orthogonal array was chosen for the experimental design. According to the Taguchi Method, the optimum G-S anode thickness and chamber pH were determined to be 1.0 cm and 8.0, respectively. A confirmatory run was performed under these optimum conditions, and the maximum power density observed was 707.75 mW·m−3. Analysis of variance (ANOVA) was conducted to identify the percentage contributions of the operating parameters to the process, which were found to be 30.66% for pH and 69.34% for anode thickness.
Survey and Characterization of Edible Fruit and Ethnomedicinal Trees in the Forest Landscape of Apayao Province
Authors: Martin Hannie T. , Tomas Olivia C. , Gabit Ryan W. , Manicad Maria Christina Z. , Rodolfo David A.
Published: September 2024

This study was conducted in the six municipalities of Apayao Province, namely, Luna, Pudtol, Flora, Conner, Kabugao, and Calanasan. This aimed to survey and characterize the edible fruit and ethnomedicinal trees in the forest landscape of Apayao province. It determined the geographical location, morphological characteristics, ecological status, DNA sequencing, phytochemical contents, uses, and threats of the edible and ethnomedicinal trees in the forests of Apayao. The methods used were qualitative and quantitative research. Fifteen (15) edible and 10 ethnomedicinal trees were surveyed with sixteen (16) families were identified.Out of 25 edible and ethnomedicinal trees, the conservation status is endangered, threatened, rare, vulnerable, and least concerned. Out of 25 edible and ethnomedicinal fruit trees, most are with identity results that range from 93 to 100% identity. Flavonoids, tannins, and sapotin compounds are mostly present in edible and ethnomedicinal trees. The community members are using 15 different ethnomedicinal trees to address 32 health-related conditions. The results of the phytochemical analyses provide support evidence to support the traditional uses of ethnomedicinal trees. All surveyed trees are susceptible to pests, diseases, and destruction brought by natural phenomena such as the effect of climate change. A policy recommendation for the conservation and protection of edible and ethnomedicinal trees is then proposed.
GIS-Based Mapping of the Water Quality and Geochemical Assessment of the Ionic Behavior in the Groundwater Aquifers of Middle Ganga Basin, Patna, India
Authors: Zafar Mohammad Masroor , Sulaiman Mohammed Aasif , Kumari Anupma
Published: September 2024

The study implemented Geographic Information System (GIS) techniques and multivariate hydrogeochemical analysis to evaluate the spatial-temporal and seasonal variation in the groundwater quality of Patna, India. For this purpose, sixty groundwater samples were collected and analyzed for major anions and cations during the pre-monsoon, monsoon, and post-monsoon seasons of 2019-2020. The physicochemical parameters such as pH, EC (Electrical Conductivity), TDS (Total Dissolved Solids), TH (Total Hardness), Ca2+, Mg2+, Na+, K+, HCO3-, Cl-, SO42- were considered to evaluate the water quality index. The result revealed degradation in groundwater quality from pre-monsoon (49.21) to post-monsoon (74.48). EC, TDS, TH, Mg2+, Na+, Ca2+, K+, and HCO3- ions were found accountable for high WQI values at various sampling sites during different seasons. Spatial maps showed that 45 % of the sampling stations exhibited poor quality in all three seasons, where the eastern part of the studied region was revealed to be the most affected area. The application of multivariate statistical methods and hydrogeochemical investigation has clearly defined the dominant role of the weathering process, and reverse ion exchange mechanism in controlling the aquifer’s ionic chemistry. Moreover, poor seepage system, and waste leachate from the surface have been found as the main cause of high levels of Na+, K+, and Cl- in the eastern part of Patna.
The Effect of Mycorrhiza and Plant Growth-Promoting Rhizobacteria Supplementation on Zea mays saccharata Sturt. Growth and Productivity Grown on Low Nutrients Soil
Authors: Nurhidayati T. , Sari L. N. , Anggraeni A. R. , Luqman A. , Shovitri M. , Kuswytasari N. D. , Saputro T. B. , Rizki H. D
Published: September 2024

Marginal land has low nutrient content (nitrogen, phosphorus, potassium). Addressing nutrient deficiencies on marginal land requires a strategic approach. Biological fertilizers like Arbuscular Mycorrhizal Fungi (AMF) and plant growth-promoting rhizobacteria (PGPR) enhance nutrient availability through symbiotic interactions. In addition, organic fertilizers such as compost could provide organic matter and improve soil structure to increase plant growth and productivity. Combining these three fertilizers with the addition of low doses of NPK fertilizer can increase the growth and productivity of maize crops on sub-marginal land. This study aims to determine the effect of AMF, consortium of PGPR, and a low dose of NPK on the growth and productivity of maize and soil nutrients on sub-marginal land by measuring plant growth up to 8 WAP (week after planting) (parameters: plant height, stem diameter, number of leaves, leaf area, chlorophyll content, stomatal density) and productivity (parameters: cob length, cob weight with husk, fresh weight, dry weight) and levels of N, P, and K elements at 8 WAP in the soil after planting. All treatments showed an increase in the level of N and K elements, while the P element showed a decrease compared to the control (soil without treatment). Moreover, each parameter did not show a significant difference, but the P2 (Compost + PGPR consortium + AMF + 50% of NPK) treatment showed the best growth and productivity. Overall, the data showed the utilization of PGPR and AMF combination was able to reduce the usage of chemical fertilizer by 50%.
Stabilization of Dredged Soil by Compensating the Sand Content in the Jhelum River
Authors: Hamid Yasir , Malik Owais Shafi , Khan Huma , Mehmood Gauhar , Zakiah Amina
Published: September 2024

River dredging is crucial for mitigating the risk of floods by enhancing the water-carrying capacity of rivers. Nevertheless, the key difficulty lies in the appropriate disposal of dredged material, resulting in escalated costs. Predominantly consisting of silt, the dredged material demonstrates constrained bearing capacity and strength. Nonetheless, there is a prospect to derive value from excavated sediments, with potential applications in diverse public works projects. The processed product derived from dredged material can serve diverse purposes, such as filling railway and highway embankments, as well as the subgrade of pavements. The comprehensive study involved analyzing the fundamental properties of the dredged material collected from the Allochibagh flood channel of the Jhelum River. The analysis focused on determining the basic geotechnical properties of the soil mass. The tests unveiled the fine and cohesive nature of the dredged soil. To enhance its properties, sand was introduced as a stabilizing agent in varying proportions. The investigation revealed an initial augmentation in compressive strength as the proportion of sand increased, attaining an optimal mixture whereafter the strength declined. This study explores the utilization of sand as a stabilizing agent for dredged soil to enhance its strength and optimize its application. The process of stabilizing dredged soil with sand demands a thorough examination of hydrogeological processes, the specific characteristics of the dredged soil, and the intricate transport of contaminants. This formal and multidisciplinary effort seeks to elevate the overall stability of the soil.
Exploring the Adsorption Efficiency of Local Apricot Seed Shell as a Sustainable Sorbent for Nitrate Ion
Authors: Ishaq Mohd , Chhipa R. C. , Sharma Anupama , Ali Gh. , Hussain Riyaz-ul
Published: September 2024

Locally available apricot seed shell as agro-waste was used for the preparation of adsorbents. The biochar was prepared at 370°C via pyrolysis and 80 mesh particle sizes were modified by 1N HCl. Nitrate adsorption and effect of co-ions from aqueous solution were studied under batch model using apricot seed shell powder (ASSP), apricot seed shell biochar (ASSB), and activated apricot seed shell biochar (AASSB). FTIR and pHPZC measurements were used to characterize the adsorbents. Based on the experimental findings, the optimum conditions follow pH 2, 0.3g dosage, initial concentration of 50 mg.L-1, and contact time of 90 min. The three forms of adsorbent exhibited good adsorption for nitrate. However, the maximum percentage removal of nitrate ions from the aqueous solution followed the order AASSB>ASSB>ASSP. The adsorption kinetic of nitrate ion was best fitted by pseudo 2nd order, and the parameters of adsorption isotherms elucidated favorable and improved sorption. This agro-waste could be used to develop sustainable adsorbents in water and wastewater treatment methods and has great potential to replace commercially available sorbents.