bluuebunny/crossref_metadata_2025 huggingface dataset:
Approximation Functionals and Their Application
Authors: Dem’yanovich A. Yuri K. , Safonova Tatjana A. , Terekhov Andrey N.
Published: September 2021

The purpose of this work is to obtain local estimates, and to calculate the constants of approximation of smooth functions. To achieve this goal, the trajectory of functionals, the concept of an approximation families of functionals, the tape of the trajectory of functionals and the width of the tape are considered. For this, the concepts of approximation functionals and their trajectories in the conjugate space are introduced, and the concepts of the trajectory tape and the tape width at a given point are discussed. The resulting overall evaluation of the approximation is applied to multidimensional cases, namely, to approximations by the Courant and Zlamal elements.
Death as a Way of Women’s Resistance: Feminist Reading of Snow and Women at Point Zero
Authors: Abbas Huda Khudhair
Published: September 2021

Women’s life without oppression, suppression and discrimination is the claim of women’s
rights. Women are subjected to discrimination or violence at various phases of life, by rules
and cultures. Unfortunately, female discrimination and oppression are rooted in the cultures
of male-dominated societies. Gender discrimination is the practice of denying or granting
privilege or rights to someone according to her/his gender, and such practice is acceptable to
both; in such societies with such practices and traditions, women’s mission for liberating
themselves is seen to be impossible because they have to challenge longstanding customs and
traditions of people. This study shed light on the practices of oppression, gender
discrimination that women encounter from infancy to adulthood, from childhood to
womanhood, as portrayed in Orhan Pamuk’s Snow and Nawal El Saadawi’s Women at Point
Zero, as well as the various ways of resistance depending on the cultural differences. Their
persistence trial to free themselves from oppression and male dominance. In Women at Point
Zero, there is a link between the triple effect of patriarchy, religion, and class on women. This
study examines how patriarchal culture, violence, oppression, and gender discrimination
happen not only in a family; in contrast, the violence does not happen from men, husbands in
families only, but again in wives, women’s resistance and reaction against them. In Snow,
women many problems related to their religious norms. The women’s discrimination is
because of using headscarves; Kadhife, the female character, is sketched as a woman who
attempts to have her right to support and defend women’s rights in her place, Kars, and to
retain wearing headscarves.
Barthes’ Semiotic Theory and Interpretation of Signs
Authors: Jadou Sara Hatem , Ghabra Iman M. M. Muwafaq Al
Published: September 2021

The current survey paper aimed to shed light on the science of signs in general, and Barthes’
semiotic theory to interpret signs in particular. In order to achieve this objective, the
researchers reviewed the prominent works of Barthes on this respect to develop an
understanding of his semiotic theory. They also displayed some conducted research applying
Barthes’ semiotic theory. The researchers also intended to answer the question: How can
researchers interpret signs using Barthes’ semiotic theory? Barthes’ major studies reviewed
were Mythologies, Elements of semiology, The five codes, The rhetoric of the image, The
death of the author, and From work to text. The conclusion answered the question in that the
focus of the theory is on three levels: denotative which describes the literal meaning,
connotative which is related to the mental concepts, and mythology which is related to the
history, and culture of viewers.
The Advent of Neoliberal Capitalism Over The 20th Century
Authors: Sharma Vridhi
Published: September 2021

In this paper, I have attempted to trace the emergence of neoliberal capitalism as an economic
system pertaining to the foundations of classical liberalism of the 18th century. The paper
essentially draws a comparative analysis of the Keynesian theory of government intervention
in economic activity as opposed to Hayek’s conceptualization of free-market capitalism,
while tracing the advent, trajectory and scope of neoliberal capitalism in the global context.
Application of Assignment Problem and Traffic Intensity in Minimization of Traffic Congestion
Authors: Rathore Rachna
Published: September 2021

In our daily life, we are facing several problems; Traffic congestion is one of them, which is
becoming serious day by day. High number of vehicles on road, insufficient infrastructure,
unreasonable developments are some reasons for increasing traffic congestion. The aim of this paper
is to introduce a mathematical model which can be applied to traffic control system having fixed
time signal with preset time to minimize traffic congestion at an intersection. In this paper, we use
the concept of traffic intensity and Assignment model for traffic congestion minimization.
Myokines secretion and their role in critically ill patients. A scoping review protocol
Authors:   School of Kinesiology, Faculty of Rehabilitation Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile, Jalil Yorschua , Gutierrez Ruvistay
Published: September 2021

Review question / Objective: 1-How and by which means stimulated muscle from critically ill patients can liberate myokines?, 2-Which are the main characteristics of the critically ill population studied and if some of these influenced myokine´s secretion?, 5-Can myokines exert local or distant effects in critically ill patients?, 5-Which are the potential effects of myokines in critically ill patients? Eligibility criteria: Participants and context: We will include primary studies (randomized or non-randomized trials, observational studies, case series or case report) that consider hospitalized critically ill adult patients (18 years or older) in risk for developing some degree of neuromuscular disorders such as ICU-AW, diaphragmatic dysfunction, or muscle weakness, therefore the specific setting will be critical care. Concept: This review will be focused on studies regarding the secretion or measure of myokines or similar (exerkines, cytokines or interleukin) by any mean of muscle activation or muscle contraction such as physical activity, exercise or NMES, among others. The latter strategies must be understood as any mean by which muscle, and there for myocytes, are stimulated as result of muscle contraction, regardless of the frequency, intensity, time of application and muscle to be stimulated (upper limb, lower limb, thoracic or abdominal muscles). We also will consider myokine´s effects, local or systemic, over different tissues in terms of their structure or function, such as myocytes function, skeletal muscle mass and strength, degree of muscle wasting or myopathies, among others.
Simulation of the saturation process of a current transformer with a load
Authors:   Branch of the National Research University ", Krutikov Kirill K. ,   MPEI",   in Smolensk, Rozhkov Vyacheslav V. ,   Branch of the National Research University "MPEI" in Smolensk, Fedotov Vladimir V. ,   The Branch of National Research University MPEI in Smolensk
Published: September 2021

The article deals with the mathematical basis and simulation of the saturation processes of current transformers with aperiodic components of short-circuit currents. Saturation processes of current transformers can affect the correct operation of the protections. At power plants, in particular atomic ones, the number of current transformers is several hundred with different loads, lengths of supply cables and the implementation of relay protection. At the same time, the determination of the time to saturation is essential for the construction of circuits and principles of construction of relay protection systems and automation of power plants. The dynamic processes in the primary and secondary circuits of current transformers in dynamics are considered in detail. A mathematical description of the dynamic processes of a current transformer in the nominal mode and during a short circuit in its primary circuit is given. The substantiation of the expediency of using the hypothesis of a rectangular magnetization characteristic in simplified calculations of saturation processes is given. The possibility of using the characteristics of magnetization in the test protocols available in practice in the no-load mode to simulate saturation processes has been demonstrated. Simulation of current transformers for the no-load experiment and power supply of the current transformer from the secondary side, as well as during its operation under conditions of a short circuit on the primary side and a known load on the secondary side is carried out. Thus, with the help of a computer experiment, it is possible to take the current- voltage characteristics and transfer them to the model with the saturation of current transformers already in the short-circuit mode. The efficiency of dynamic simulation of current transformers is shown. The software implementation of the model is performed by means of structural simulation in the MatLab package, based on the solution of equations of matrix structures and emulation of parallel computations. It was found that with the adequacy of the model and the real current transformer with the involvement of information from the no-load mode, the determination of the magnetization time from the aperiodic current components from the model is much easier than the analysis by other existing methods. They require detailed design details of the current transformer and the magnetic properties of the steel.
A computer program for electromechanical system operational diagnostics based on the topological approach
Authors:   Branch of the National Research University ", Kurilin Sergey P. ,   MPEI",   in Smolensk, Sokolov Andrey M. ,   Branch of the National Research University "MPEI" in Smolensk, Prokimnov Nikolai N. ,   Synergy University
Published: September 2021

The paper presents a method, a mathematical model, and a computer program for the operational diagnostics of an electromechanical system (EMS). During EMS operation, service aging changes the properties of the parametric matrices of the windings and, as a consequence, the characteristics of the EMS vector space. Periodic testing of the vector space offers relevant and reliable data on the current health of the EMS, its changes during operation, and the risk of loss of function. The object of the study is an asynchronous electric motor (AEM). It is urgent to automate the process of assessing the current health of an AEM and to organize the storage of information on its states at different stages of its life cycle. To solve the problem, software (SW) for accumulation of information on AEM operation and for evaluation of its basic performance metrics has been developed in the Python programming language. The SW is based on the topological approach to diagnostics, which implies the analysis of the current responses of motor rotor windings to phase voltage pulses. The SW enables one to determine the rate of the service aging of an item, the probability of its survival and residual life, to obtain access to the history of previous diagnostics, and to visualize the in-service history of the above-mentioned performance metrics. The developed SW can be used to increase the AEM operation efficiency and to plan engineering or repair work; it can also be used as an information source for re- engineering and modification of existing AEMs. The described SW can be extended to perform operational diagnostics based on the topological approach of devices of various types. Also, this SW can be considered as a separate information component of the digital twin of a complex EMS, which will allow us to study the main indicators of its reliability, fault tolerance and operational efficiency at all stages of the life cycle.
An electric power system object model creating experience for researching the operation of digital means of relay protection and automation
Authors:   Branch of the National Research University ", Doletskaya Larisa I. ,   MPEI",   in Smolensk, Ziryukin Vladislav I. ,   Branch of the National Research University "MPEI" in Smolensk, Solopov Roman V. ,   The Branch of National Research University MPEI in Smolensk
Published: September 2021

The article is devoted to the operation logic modeling of relay protection and automation terminals in order to their verification, adjustment and further exploitation. The problem of adjusting protection terminals mutual interaction is unlikely to appear in real conditions due to wide variety of them. The authors propose a solution to this problem by creating a verified model based on a digital twin of an electric power network section created in the MatLab software package. This model helps to study the functioning of the researched protection settings in nominal, repair, emergency and post-emergency equipment operation modes. A model of the selected substation was created displaying all the properties that are significant for research of the original one. In addition, the requirements analysis for the main and backup protection operation settings of the three-winding transformers was carried out. The main unit is a differential transformer relay protection and the backup one is maximal current protection in amount of three units for every transformer winding circuit: higher, middle and lower transformer voltage branch. The model makes it possible to analyze the relay protection operation selectivity by checking the current settings which could be imported from XML documents unloaded from existing terminals and to evaluate the correctness of new calculated ones with the possibility of their manual input. As a result of the researched object modeling, a three-stage operation analysis of the differential and maximal current protections was carried out. It has shown relay protection selective operation both in the case of nominal and abnormal modes, including the event of the main transformer protection malfunction. This technique can be extended to the other electric power network.
Virtualization of information object vulnerability testing container based on DeX technology and deep learning neural networks
Authors:   Branch of the National Research University ", Okunev Boris V. ,   MPEI",   in Smolensk, Lazarev Alexey I. ,   Branch of the National Research University "MPEI" in Smolensk, Kharlamov Pavel S. ,   The Branch of National Research University MPEI in Smolensk
Published: September 2021

The modern development of information security tools, along with the improvement of remote access methods, allows software and hardware to be audited without the need for direct access to the system under test. One of its components is related to the implementation of software on mobile ARM processor architectures. Within this direction of development, the approach that allows integrating Linux kernel-based distributions by introducing a virtual container chroot (change root) into the Android OS- based system and, consequently, performing penetration testing without the need to use personal computers is highlighted. An example of this approach is the Kali NetHunter distribution which allows remote system administration functionality through the KeX module. Besides the obvious advantages of KeX functionality, some disadvantages should also be mentioned: firstly, the low speed of GUI processing due to translation to remote hosts and the need to support translation at operating system level; secondly, the consumption of energy resources when using the desktop features of the KeX module. In order to solve the mentioned problems, a system of virtualization of energy-efficient container for testing the vulnerabilities of critical information objects has been developed and based on the principle of multi-containerization. The software of the system is represented by two components: an enlarged module for integration of the chroot container into the DeX environment (primary), and an enlarged module for ensuring energy efficiency using predictive neural network models based on variable time intervals (secondary). As a result of comparing the effectiveness of existing and implemented approaches in penetration testing, it is noted that the proposed system can be used in testing the security of particular platforms and systems, including highly sensitive information objects or resources.
Phenotipic pigmentary traits – important risk factors for skin cancer
Authors:   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, GRIGORE Mariana ,   Clinica I Dermatologie, Spitalul Clinic Colentina, Bucureşti, AVRAM Alina ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

Prevention and early detection in skin cancer are of utmost importance as they increase survival rates, life quality indicators and overall prognosis. In order to achieve an optimal primary prophylaxis one must first know and recognise documented risk factors. The colour of skin, hair and eyes were linked to the risk of developing skin cancer and are easy to evaluate morphologic traits. Pigmentary phenotypic traits are used worldwide to evaluate an individual’s risk for cutaneous carcinogenesis. A high number of epidemiologic studies highlight the importance of skin type as an independent skin cancer risk factor, fair skin and the inability to tan being frequent characteristics of patients suffering from this pathology. Regarding eye colour, there is less scientific data available, but most published studies link light irises to the risk of developing skin cancer.
Rheumatoid arthritis – a subject always in actuality
Authors:   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, BALTA Mihaela Daniela ,   Policlinica Vitan, Bucureşti, MATEI Dumitru ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti,   Institutul de Ocrotire a Mamei şi Copilului „Alfred Rusescu“, Bucureşti, MILICESCU Mihaela ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti,   Clinica de Medicină Internă şi Reumatologie, Spitalul Clinic „I. Cantacuzino“, Bucureşti, ŞERBAN Teodora ,   Clinica de Medicină Internă şi Reumatologie, Spitalul Clinic „I. Cantacuzino“, Bucureşti, VUTCANU Oana ,   Clinica de Medicină Internă şi Reumatologie, Spitalul Clinic „I. Cantacuzino“, Bucureşti, BOJINCĂ Mihai ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti,   Clinica de Medicină Internă şi Reumatologie, Spitalul Clinic „I. Cantacuzino“, Bucureşti
Published: September 2021

Aim. The main objective of this study is represented by a clinical and epidemiological evaluation of the impact that biologic therapy exerts on patients suffering from rheumatoid arthritis. Material and methods. We have performed a study on a lot made up of 92 patients with rheumatoid arthritis, treated and accounted for inside the Rheumatology Clinic of Cantacuzino Hospital Bucharest, where they underwent biologic therapy, and we have analyzed the epidemiological, clinical and paraclinical data, establishing correlations with the received therapy. Results. Results show that the lot was predominantly made up of patients from urban areas, with an average education level. Men have presented higher percentages of highly seropositive forms, whereas women had higher DAS 28 and increased ESR levels, as well as more frequently associated cardiovascular pathology, dyslipidemia and diabetes mellitus. A connection between the evolution of the disease and the number of births could not be confirmed. Smokers have recorded different responses to biologic therapy. Dyslipidemia was present in 69.6% of the patients, but cholesterol levels did not positively correlate with inflammation markers and were not influenced by treatment in order to establish a statistical significance, although patients treated with etanercept presented decreased levels of cholesterol. 89.1% of patients with dyslipidemia already had statins included in their therapy. The evolution of DAS 28 and ESR in the studied lot was in favor of patients treated with adalimumab and rituximab. Conclusions. An urban lifestyle, the level of education (an average level), gender, menopause, and smoking as well as intensely positive serology have all represented factors which determined the onset and evolution of rheumatoid arthritis. Smokers exhibited decreased responses to biologic therapy.
Acute respiratory infections in children from an ENT perspective
Authors:   „Grigore Alexandrescu“ Clinical Hospital for Children, Bucharest, ZAMFIR-CHIRU-ANTON A. , MANEA N. ,   „M.S. Curie“ Emergency Clinical Hospital for Children, Bucharest,   „Carol Davila“ University of Medicine and Pharmacy, Bucharest, GHEORGHE D.C. ,   „M.S. Curie“ Emergency Clinical Hospital for Children, Bucharest,   „Carol Davila“ University of Medicine and Pharmacy, Bucharest
Published: September 2021

Background. Adenoidectomy remains a frequent surgical approach for recurrent upper respiratory tract infections (URTI) in children. We research if only age and collectivity are responsible for recurrences, or other anatomic conditions can account for the history of the patient. Design. Retrospective case series review. Material and method. Questionnaire about respiratory symptoms and correlations observed between the history of the patient and the presence or absence of short soft palate. Results. 102 children could provide enough data to be included in the study. Frequent URTI were observed in 30% of the affected children and only 16% of their normal peers. 41% of URTIs each persisted longer than 10 days in short soft palate children vs. 17% in normal patients. Broncho-pulmonary complications were encountered in 44% of children with short palate as opposed to 27% in others. Conclusions. Short velli palatini can disturb normal swallowing process and allow rhinopharyngeal chronic inflammation. That can lead to persistent recurrent URTIs, more probable chronic obstruction through the adenoids and other diseases in pediatric ENT practice.
Childhood obesity – a serious problem in our society
Authors:   Disciplina Medicină de Familie, Universitatea de Medicină și Farmacie „Carol Davila“, Bucureşti, IANCU Mihaela Adela , MATEI Dumitru ,   Disciplina Medicină de Familie, Universitatea de Medicină și Farmacie „Carol Davila“, Bucureşti, BEJAN Gabriel Cristian ,   Disciplina Medicină de Familie, Universitatea de Medicină și Farmacie „Carol Davila“, Bucureşti
Published: September 2021

The childhood obesity is a serious public health problems. The prevalence of childhood obesity is on the rise. The most recent recommendations regarding prevention of childhood obesity focus on increased exercise and improved diet to prevent childhood obesity and on incresed prevention of perinatal factors that determine the development of childhood obesity. Material and method. During 2013-2015 we evaluated a number of 78 patients. We took a standardized history, performed a physical examination, measured height, weight, blood pressure, heart rate, calculated body mass index. Also we analyzed the results of plasma serum glucose, blood lipid levels and liver transaminaze levels. Conclusions. Low birth weight and prematurity can be considered predisposing factors for obesity. We observed an increase in the average total cholesterol and in the average alanine transaminase in obese children group compared to the overweight children group.
Basic special needs and related approaches – mainly medical – for patients following moderate/severe traumatic brain injury
Authors:   Physical (Neural-Muscular) and Rehabilitati on Medicine Clinic Division,  „Bagdasar-Arseni“ Teaching Emergency Hospital, Bucharest, Romania, POPESCU Cristina ,   „Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania, ANGHELESCU Aurelian ,   Physical (Neural-Muscular) and Rehabilitati on Medicine Clinic Division,  „Bagdasar-Arseni“ Teaching Emergency Hospital, Bucharest, Romania,   „Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania, DAIA Cristina ,   Physical (Neural-Muscular) and Rehabilitati on Medicine Clinic Division,  „Bagdasar-Arseni“ Teaching Emergency Hospital, Bucharest, Romania,   „Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania, ONOSE Gelu ,   Physical (Neural-Muscular) and Rehabilitati on Medicine Clinic Division,  „Bagdasar-Arseni“ Teaching Emergency Hospital, Bucharest, Romania,   „Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania
Published: September 2021

Traumatic brain injury (TBI) may affect almost every aspect of a person’s life. The relationships with family and friends, their roles and responsibilities, all, will require an adjustment period, preferably to be achieved one step at a time, with training and guidance of a specialized health care team. Consequently, such neurologically severe impaired patients have almost always including long term needs, which are quasi-permanent or permanent so endured for a life time. The only way these special needs can be fulfilled or – at best made unnecessary – is the discovery of the way to cure the central nervous system lesions. Because medicine is unfortunately not there yet, this article will review the respective specific numerous long-term needs that may be met by the tools medicine has to offer today, aiming to improve health care in hospital units with rehabilitation profile and to provide ongoing guideline constructs for patients with TBI and their families, after discharge too, aiming at an as complete as possible family social and professional reintegration. Post TBI evolution is influenced by a variety of factors making patients with brain injuries care a complicated and sustained process, the improvements being undoubtedly influenced by their multimodal way to be approached within interdisciplinary teams, applying individualized rehabilitation programs – all in purpose to reach a quasi-normal life or as close to its sense.
Current synthetic overview on spinal cord injury epidemiological data
Authors:   Teaching Emergency Hospital „Bagdasar-Arseni“ (TEHBA), Bucharest, Romania, ANDONE Ioana ,   „Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania, ANGHELESCU Aurelian ,   Teaching Emergency Hospital „Bagdasar-Arseni“ (TEHBA), Bucharest, Romania,   „Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania, DAIA Cristina ,   Teaching Emergency Hospital „Bagdasar-Arseni“ (TEHBA), Bucharest, Romania,   „Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania, ONOSE Gelu ,   Teaching Emergency Hospital „Bagdasar-Arseni“ (TEHBA), Bucharest, Romania,   „Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania
Published: September 2021

Aim. To have updated information on the epidemiology of spinal cord injury (SCI) is required for developing an adequate and effective related health policy strategies and consequent contextual decisions making regarding this category of patients and also for planning and implementing SCI prevention education and measures. Accordingly, the rationale of this article is to provide a systematic overview of the literature regarding SCI epidemiology. Material and methods. We reviewed epidemiological published reports and searched on internet specifically databases, from different centres, worldwide, about SCI, collecting descriptive data for properly estimating the incidence, prevalence, and/ or causes of SCI. Results. The global annual incidence rate is considered to be 23 cases of Traumatic Spinal Cord Injury (TSCI) per million (179,312 new cases per annum – results provided by World Health Organisation’s (WHO) in 2007). Prevalence per million inhabitants varies quite largely among statistics in different countries (from 280 in Finland to 681 in Australia, 755 in the United States of America or maybe even more, and even bigger in Canada). Men more commonly suffer from this kind of pathology and the direction of SCI evolution is to have a higher cord lesion level (more tetraplegics than paraplegics) and age at injury. Conclusion. Even if the results of this literature review showed that the SCI incidence and prevalence are rising, they did not suffer significant changes in the last three decades of time. The prevalence surveys remain poor, mainly because a basic requirement for having correct and appropriately updated figures would need national and or regional electronic dedicated registers of evidence, and this is not a situation frequent enough. But the incidence studies from USA and Europe have been increased in the last years. This article asserts the need for improving the SCI data standardised collection in many countries, especially in the ones from low developed or emergent areas.
Rotational thromboelastometry (ROTEM) – a new diagnostic method for assessment of hemostatic response in multiple trauma patient
Authors:   Clinica Anestezie Terapie Intensivă, Spitalul Clinic de Urgenţă Bucureşti, GRINŢESCU Ioana Cristina , MIREA Liliana ,   Clinica Anestezie Terapie Intensivă, Spitalul Clinic de Urgenţă Bucureşti,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, BEURAN Mircea ,   Clinica de Chirurgie Generală, Spitalul Clinic de Urgenţă Bucureşti,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, GRINŢESCU Ioana Marina ,   Clinica Anestezie Terapie Intensivă, Spitalul Clinic de Urgenţă Bucureşti,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

The coagulopathy is one of the most frequent causes of early posttraumatic mortality. The changes induced by multiple trauma in the coagulation cascade lead to different shapes: from massive bleeding to thrombosis, with different time evolution. Acute intrinsic coagulopathy arising in severely injured trauma patients is now termed trauma-induced coagulopathy (TIC) and is an emergent property of tissue injury combined with hypoperfusion. Mechanisms contributing to TIC include: coagulation factor and platelet consumption, platelet dysfunction, hyperfibrinolysis. But it also could be induced by iatrogenic factors such as: massive transfusion, hypothermia, quantity and type of replacement solutions. Rotational thrombelastometry (ROTEM) is a rapid method to diagnose the type of coagulopathy, showing graphical and numerical data and provides information on the rapidity of coagulation initiation, kinetics of clot growth, clot strength and breakdown by measuring the viscoelastic changes of clot formation in whole blood under low shear conditions. This method can give a „big picture“ of the coagulation cascade, and it can represent a start for the coagulopathy treatment guideline in multiple trauma.
The concept of tonsillar outbreak infection
Authors:   Institutul Naţional de Neurologie şi Boli Neurovasculare, Bucureşti, TOADER Corneliu , TOADER Mioriţa ,   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“, Bucureşti, MITEA Gabriela ,   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“, Bucureşti, CONSTANTIN Anca ,   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“, Bucureşti, NICULESCU Liviu ,   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“, Bucureşti, DRĂGHICI Mircea ,   Dentirad Hospital, Ploieşti, PALADE Dragoş ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi
Published: September 2021

Tonsillar outbreak infection is an non-discharging inflammatory disease of the connective tissue, with multiple organ manifestations, with a self-timing nature, being chronologically and etiopathogenically linked to the infection with beta-hemolytic streptococcus group A. An important role for the emergence and persistence of the outbreak infection is assigned to the poor local immunity, which is translated, among others, by low levels of serum and secretory IgA in upper respiratory mucosa. Tonsil immune pathology is at the origin of various diseases, mainly cardiac and renal. We present some data regarding the concept of tonsillar infection, hoping to help the physicians in making better decisions for the amigdalectomy indication.
The microsurgical solution in supratentorial cavernous angiomas
Authors:   Department of Neurosurgery, „Bagdasar-Arseni“ University Hospital, Bucharest, Romania, SASARAN A. , MOHAN A. ,   Bihor County University Hospital, Oradea, Romania, MOISA H.A. ,   „Carol Davila“ University School of Medicine, Bucharest, Romania, CIUREA A.V. ,   „Carol Davila“ University School of Medicine, Bucharest, Romania,   Sanador Medical Center Hospital, Bucharest, Romania
Published: September 2021

Cavernous angiomas of the central nervous system are rare, neurovascular lesions usually detected in patients aged 20-50 and represent up to 8-15% of all intracranial malformations. The association between cavernomas and arteriovenous malformations is met in 10-30% of cases. Treatment strategies for intracranial cavernomas include conservative management, open microsurgery and finally stereotactic radiosurgery (the use of which is still highly debatable as there are no available methods to determine its short term effects). The authors present their surgical experience in what regards a cohort of 149 consecutive patients, diagnosed with intracranial and supratentorial cavernomas, admitted, investigated and treated between January 2000 and January 2015. The clinical particularities of the patients together with the surgical approaches are debated. Last but not least the outcome and quality of life of the patients is discussed.
The management of latent tuberculosis infection in Romania – limits and perspectives
Authors:   Institutul de Pneumoftiziologie „Marius Nasta“, Bucureşt, BĂLTEANU Mara , TĂNĂSESCU Mihaela ,   Institutul de Pneumoftiziologie „Marius Nasta“, Bucureşt, CIOLAN Gina ,   Institutul de Pneumoftiziologie „Marius Nasta“, Bucureşt, MARICA Constantin ,   Institutul de Pneumoftiziologie „Marius Nasta“, Bucureşt,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

In 2014 the World Health Organization adopted a new strategy for tuberculosis control – infectious disease with the highest mortality in the world after AIDS. This new strategy – The End TB Strategy – is aimed to reducing tuberculosis disease by 90% and tuberculosis mortality by 95%, so that by 2035 TB is no longer considered a problem global public health. The World Health Organization report on tuberculosis published in 2014 is estimated that about one third of the world population is infected with M. tuberculosis (approx. 2 billion); 5-10% of them will develop active disease, thus fullfiling the TB pandemia. It is therefore an essential objective to diagnose these cases of latent tuberculosis infection and to establish precise criteria of the latent TB infection treatment. Tuberculin skin test is the most important test for emphasis of TB infection in an organism. The results obtained in recent years in mycobacterial genomics and human cell immunology have led to the development of other tests that detect tuberculosis infection, of which the most commonly used is the test that measures the release of IFN-γ (Interferon gamma-releasing assay IGRA). Any patient with increased risk of infection to disease progression and who has a positive skin test is a candidate for treatment. Immuno-compromised patients (HIV infected, treatment with anti-TNF, organ transplantation, immunosuppressive medication) with LTBI have a higher risk of reactivation. Immuno-compromised patients with LTBI should receive treatment.
Prostate cancer tumor markers
Authors:   „Carol Davila“ University of Medicine and Pharmacy, Bucharest, BACALBASA Nicolae , GIREADA Alexandra ,   „Carol Davila“ Central Military Emergency Hospital, Bucharest, BALESCU Irina ,   „Ponderas“ Hospital, Bucharest, BRASOVEANU Vladislav ,   „Dan Setlacec“ Center of Gastrointestinal Diseases and Liver Transplantation, Fundeni Clinical Institute, Bucharest, BALALAU Cristian ,   „Sf. Pantelimon“ Emergency Hospital, Bucharest
Published: September 2021

Prostatic cancer represents an important health problem worldwide, being the third most common malignancy in men older than 55 years, after pulmonary and colon cancer. In early stages prostatic cancer remains hard to be diagnosed at clinical or imagistical studies, the most efficient way to detect it being based on the determination of tumor markers. This is a literature review of the largest studies conducted on the theme of prostatic tumor markers.
Health care team in rural areas – past, present and future
Authors:   Facultatea de Medicină, Farmacie şi Medicină Dentară, Universitatea de Vest „Vasile Goldiş“, Arad, JOMPAN Afilon
Published: September 2021

The role of the family doctor in a properly established health system is to provide primary health care, family assistance and nursing. Today it is inconceivable that, in absence of the health care team, to meet its obligations and health indicators to be improved.
Correlations between serum bilirubin, leukocytosis and anatomo-pathological form in acute appendicitis
Authors:   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, ŞERBAN Dragos , BRANESCU Cristian ,   Spitalul Universitar de Urgenţă Bucureşti, SAVLOVSCHI Costel ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, TUDOR Corneliu ,   Spitalul Universitar de Urgenţă Bucureşti, BORCAN Răzvan ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, NICA Adriana ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, VANCEA Geta ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, DASCĂLU Ana-Maria ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti
Published: September 2021

The prevalence of acute appendicitis as the number 1 inflammatory disease, occurring in 1 out of 500-600 inhabitants of the world population, has made it imperative for us to study the pathology of the inflammation in the presurgery stage. The present paper is a retrospective study, conducted on 147 patients diagnosted and operated for acute appendicitis in our clinic, between October, 1st, 2009 and January, 15th, 2012. The pre-surgical stage comprised clinical data, and also an important number of paraclinical data, out of which, for the purpose of this presentation, we selected bilirubin and leukogram. These pre-surgery biological markers were correlated to the post-operatory pathological anatomy results. These results confirmed our hypothesis that the paraclinical stage in diagnosing the acute appendicitis consists in the inflammation prognosis factors, which can be highlighted through a complex paraclinical range of methods, later confirmed by both the clinical stage, and its anatomo-pathological forms.
Depression in some categories of diabetes patients
Authors:   Spitalul Clinic „Nicolae Malaxa“, Clinica Diabet, Nutriţie şi Boli Metabolice, Bucureşti, DOBJANSCHI Carmen , CULMAN Mirela ,   Institutul Naţional de Diabet, Nutriţie şi Boli Metabolice „N.C. Paulescu“, Bucureşti
Published: September 2021

Depression increases the risk of diabetes but depressive symptoms are more common in type 1 and type 2 diabetes patients with micro- and macrovascular complications. Women with diabetes should be also closely monitored for signs of postpartum depression that may be difficult to distinguish from the normal sequelae of childbirth. For people who have diabetes and depression, treating depression can raise quality of life and increase blood glucose control. Comorbid depression and diabetes represent a major public health challenge through increased health care consumption and health care expenditure. Coordinated clinical care requires the implementation of effective strategies to increase the recognition of depression and the adoption of evidence-based interventions. Studies examining mechanisms and interventions are necessary.
Psychological aspects of patients with encopresis associated with chronic constipation
Authors:   Universitatea de Medicină şi Farmacie „Gr. T. Popa“ Iaşi, OLARU Claudia , IORGA Magdalena ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“ Iaşi, OLARU Radian Alexandru ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“ Iaşi, GIMIGA Nicoleta ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“ Iaşi, SOPONARU Camelia ,   Universitatea „Al. I. Cuza“ Iaşi, DIACONESCU Smaranda ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“ Iaşi
Published: September 2021

Chronic constipation is an extremely common and costly condition that can negatively impact the patient’s quality of life, resulting in a major economic and social burden. Most patients do not understand their situation and suffer from social isolation. The developmental particularities of the child cause the etiology and symptomatology of constipation to differ from those described by adults, which requires a specific management in terms of diagnosis and treatment. The specialty literature to date relies on fragmented studies focused on these particularities, as well as on the multitude of aspects of diagnostic and treatment related to chronic stool retention and bowel evacuation in children. The problem that is being studied is important not only from a medical and socioeconomic point of view, but also because some complications caused by chronic constipation (such as encopresis and enuresis) lead to the social isolation and physical and psycho-emotional impairment of these children.
Soft tissue coverage types for complex limb trauma in children
Authors:   Facultatea de Medicină, Universitatea „Titu Maiorescu“, Bucureşti, MATLAC Ileana-Carmen , ENESCU Dan Mircea ,   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“,  Clinica de Chirurgie Plastică şi Microchirurgie Clinică Reconstructivă, Bucureşti,   Spitalul Clinic de Urgenţă pentru Copii „Grigore Alexandrescu“,  Clinica de Chirurgie Plastică şi Microchirurgie Clinică Reconstructivă, Bucureşti
Published: September 2021

Objective. The analysis of the soft tissue coverage types employed in complex limb trauma in children towards a potential subsequent optimization of their management. Materials and methods. Data regarding the children admitted to the Burns and Plastic Surgery Clinic of ‘Grigore Alexandrescu’ children’s hospital, between 2005 and 2013 with complex limb trauma requiring soft tissue coverage was obtained from the surgical protocols. Information was gathered regarding patients’ sex and age, the type of incident, the mode of occurence, the region in need of coverage, the number and type of surgical procedures, as well as regarding the type of coverage employed. Results. A number of 80 children required soft tissue coverage in complex limb trauma. Boys accounted for approximately two thirds of all cases. The pacients had a minimum age of 1 year and a maximum one of 16 years. There were approximately 50% more trauma of this type affecting the upper limb than the lower one. The fingers required coverage in the majority of cases (77.5%). In the majority of cases at this level (77%) split-level thickness grafts and local flaps were applied. Conclusions. The majority of the complex pediatric soft tissue limb coverage cases were boys. Fingers were the predominantly affected area and most often the usage of split-level thickness grafts or of local flaps was required. The accidents were predominantly home related. The cases had an uncomplicated evolution, the coverage solutions employed being successful in over 90% of the situations.
The Impact of Accounting Fundamentals and Macroeconomic Indicators on Manufacturing Companies' Stock Prices
Authors: Shih Van hyung , Hoang Chien
Published: September 2021

The aim of this research is to ascertain if accounting fundamentals and macroeconomic indicators have an effect on stock prices. In this research, a quantitative method was used. The population of this research includes manufacturing firms listed on the Stock Exchange, with a sample size of ten companies collected through secondary data during the 2019-2020 quarter. Scale of data measurement using a ratio scale. The findings indicated that inflation and interest rate macroeconomic variables had little impact on stock values. Fundamentals of Accounting The return on equity and the price-earnings ratio both have a substantial beneficial impact on company prices
Employees' Knowledge and Skills on Work Productivity at the Manpower Department
Authors: Nishu Sarthek , Lalrinzuala Akash
Published: September 2021

The purpose of this research is to evaluate the impact of improving staff knowledge and skills on job productivity. This study employs a descriptive quantitative approach. The findings of this research show that increasing knowledge has a positive and significant impact on job productivity, with tcount = 4.236 > ttable = 1.674 and a significance level of 0.000 0.05. While the employee competence variable has a positive and substantial impact on job production (tcount = 3.143 > ttable = 1.674 with a significant 0.003 0.05)
A EDUCAÇÃO EM VIAS DE LIBERTAÇÃO
Authors: Leal Rayane
Published: September 2021

O artigo tem como propósito apresentar uma reflexão sobre a educação para jovens e adultos, bem como a formação docente no contexto latino-americano. Busca também analisar e, por isso mesmo, resgatar o contexto histórico, cultural e social da América Latina através de uma análise filosófica em vias de libertação. Tal proposta se justifica pela importância de uma educação latino-americana contextualizada, popular e democrática que contribua para a formação de identidade dos sujeitos, bem como sua autoestima como educandos. Esta investigação se apresenta como um farol em tempos sombrios, re-pensando e re-construindo o contexto educativo a partir das perspectivas pedagógica e filosófica de Enrique Dussel (1971) e Paulo Freire (1996) com ênfase nas categorias: Utopia e Amorosidade.
Bridging the Gap 2021- Report
Authors: Chakravorty Indranil , Daga Sunil , Sharma Shivani , Chakravorty Subarna , Fischer Martin , Mehta Ramesh
Published: September 2021

Bridging the Gap- Workshop series 2020-21

This is the full report and discussions in the consensus building workshops and highlights of the thematic synthesis.
TRAO Survey of the Nearby Filamentary Molecular Clouds, the Universal Nursery of Stars (TRAO FUNS). II. Filaments and Dense Cores in IC 5146
Authors: Chung Eun Jung , Lee Chang Won , Kim Shinyoung , Gopinathan Maheswar , Tafalla Mario , Caselli Paola , Myers Philip C. , Liu Tie , Yoo Hyunju , Kim Kyoung Hee , Kim Mi-Ryang , Soam Archana , Cho Jungyeon , Kwon Woojin , Lee Changhoon , Kang Hyunwoo
Published: September 2021

We present the results on the physical properties of filaments and dense cores in IC 5146, as a part of the TRAO FUNS project. We carried out on-the-fly mapping observations using the Taeduk Radio Astronomy Observatory (TRAO) 14 m telescope covering about 1 square degree of the area of IC 5146 using various molecular lines. We identified 14 filaments (24 in total, including sub-filaments) from the C18O (1–0) data cube and 22 dense cores from the N2H+ (1–0) data. We examined the filaments’ gravitational criticality, turbulence properties, accretion rate from filaments to dense cores, and relative evolutionary stages of cores. Most filaments in IC 5146 are gravitationally supercritical within the uncertainty, and most dense cores are formed in them. We found that dense cores in the hubs show a systemic velocity shift of ∼0.3 km s−1 between the N2H+ and C18O gas. Besides, these cores are subsonic or transonic, while the surrounding filament gas is transonic or supersonic, indicating that the cores in the hubs are likely formed by the dissipation of turbulence in the colliding turbulent filaments and the merging is still ongoing. We estimated a mass accretion rate of 15–35 M
⊙ Myr−1 from the filaments to the dense cores, and the required timescales to collect the current core mass are consistent with the lifetime of the dense cores. The structures of filaments and dense cores in the hub can form from a collision of turbulent converging flows, and mass flow along the filaments to the dense cores may play an important role in forming dense cores.