bluuebunny/crossref_metadata_2025 huggingface dataset:
The migraine landscape on YouTube: A review of YouTube as a source of information on migraine
Authors: Saffi Hillah , Do Thien Phu , Hansen Jakob Møller , Dodick David W , Ashina Messoud
Published: July 2020

Introduction

YouTube is the most widely used video hosting website in the world; however, the quality and reliability of information is unknown. The aim of this study is to evaluate the content and distribution of the most popular videos on YouTube about migraine.

Methods

We searched for migraine-related videos on the online video hosting resource YouTube ( http://youtube.com/ ). Two authors screened the titles and video descriptions independently for all videos with a view count of ≥ 10,000 views. For each video we recorded descriptive data, the source/author and the primary purpose/content.

Results

We identified 351 eligible videos. In total, there was more than 3 days of content viewed more than 163 million times. Only 9% of these videos were authored by healthcare professionals. The majority (44%) of videos focused on complementary and alternative medicine.

Discussion

YouTube provides a wide array of easily accessible information on migraine, ranging from authoritative sources to potentially questionable content. If used uncritically, this may result in inadequate clinical management. Peer-reviewed information on migraine mechanisms and treatment is needed to provide the best available evidence for the public and patients. Ideally, a professional society or foundation such as the International Headache Society would develop, curate, and distribute content.
Pothole Mapping and Patching Quantity Estimates using LiDAR-Based Mobile Mapping Systems
Authors: Ravi Radhika , Habib Ayman , Bullock Darcy
Published: July 2020

Pavement distress or pothole mapping is important to public agencies responsible for maintaining roadways. The efficient capture of 3D point cloud data using mapping systems equipped with LiDAR eliminates the time-consuming and labor-intensive manual classification and quantity estimates. This paper proposes a methodology to map potholes along the road surface using ultra-high accuracy LiDAR units onboard a wheel-based mobile mapping system. LiDAR point clouds are processed to detect and report the location and severity of potholes by identifying the below-road 3D points pertaining to potholes, along with their depths. The surface area and volume of each detected pothole is also estimated along with the volume of its minimum bounding box to serve as an aide to choose the ideal method of repair as well as to estimate the cost of repair. The proposed approach was tested on a 10 mi-long segment on a U.S. Highway and it is observed to accurately detect potholes with varying severity and different causes. A sample of potholes detected in a 1 mi segment has been reported in the experimental results of this paper. The point clouds generated using the system are observed to have a single-track relative accuracy of less than ±1 cm and a multi-track relative accuracy of ±1–2 cm, which has been verified through comparing point clouds captured by different sensors from different tracks.
The feasibility of degradable glass microspheres as transient embolic medical devices
Authors: Doucet Jensen , MacDonald Kathleen , Lee Changseok , Hana Renato Abu , Soulez Gilles , Boyd Daniel
Published: July 2020

The deliberate occlusion of blood flow through transarterial embolization is currently being used to treat conditions ranging from hemorrhages to hypervascular tumors. Degradable, imageable high borate glass microspheres (BRS2) were developed and tested to improve lesion targeting and promote a temporary vascular occlusion which is sufficient for most embolization procedure. A 48 hour pilot study, in a swine renal model, was conducted to assess the embolization effectiveness and potential risks of this new embolic agent. Bilateral embolization of the caudal branch of the renal arteries using test and control particles were performed in 4 pigs. Embolization efficacy, recanalization and resulting ischemia were evaluated at different time frame (0, 24 and 48 hours). The primary outcomes for this study were the assessment of: (i) embolization effectiveness, and (ii) vessel recanalization. The test article was found to occlude vessels as effectively as the control microspheres, with the use of a smaller volume of microspheres. At the 24 hour time point, over 95% of the material was found to be completely degraded, although little to no recanalization was observed. This data suggests that BRS2 is an effective embolic agent, however further investigations into the method of delivery are required prior to clinical implementation.
Using Automatic Assessment of Speech Production to Predict Current and Future Cognitive Function in Older Adults
Authors: Ostrand Rachel , Gunstad John
Published: July 2020

Neurodegenerative conditions like Alzheimer disease affect millions and have no known cure, making early detection important. In addition to memory impairments, dementia causes substantial changes in speech production, particularly lexical-semantic characteristics. Existing clinical tools for detecting change often require considerable expertise or time, and efficient methods for identifying persons at risk are needed. This study examined whether early stages of cognitive decline can be identified using an automated calculation of lexical-semantic features of participants’ spontaneous speech. Unimpaired or mildly impaired older adults (N = 39, mean 81 years old) produced several monologues (picture descriptions and expository descriptions) and completed a neuropsychological battery, including the Modified Mini-Mental State Exam. Most participants (N = 30) returned one year later for follow-up. Lexical-semantic features of participants’ speech (particularly lexical frequency) were significantly correlated with cognitive status at the same visit and also with cognitive status one year in the future. Thus, automated analysis of speech production is closely associated with current and future cognitive test performance and could provide a novel, scalable method for longitudinal tracking of cognitive health.
Design and verification of enhanced CFRTPCs fabrication technique using fused deposition modeling
Authors: Naveed Ali Bin , Butt Shahid Ikramullah , Mubashar Aamir , Chaudhry Fausz Naeem , Qadir Najam ul , Faping Zhang
Published: July 2020

Research shows that mechanical properties of parts produced using fused deposition modeling (FDM) are inferior when compared to parts produced using conventional techniques such as injection molding. Efforts have been made in recent years to improve mechanical properties by reinforcing the parts with high strength fibers. This has been achieved by either modifying FDM setups to extrude fibers with thermoplastics and fabricate continuous fiber reinforced thermoplastic composites (CFRTPCs) or employing manual techniques subsequent to part production. Existing CFRTPCs fabrication procedures have limitations of fiber exposure to environment, no direct control method for volume fraction, and poor surface finish. This research work is focused on improving the process of producing CFRTPCs by addressing these limitations using a dual extruder FDM setup. The process developed was tested for its feasibility using Kevlar fiber as reinforcement for commercially available ABS, PLA, PLA-C, and PLA-Cu thermoplastic fibers. Taguchi L16 orthogonal array was used to design experiments, while tensile and flexural testing was performed to determine mechanical properties achieved. Tensile strength was improved up to 3 times the baseline value of thermoplastics, while flexural strength was improved up to 1.6 times. This technique can further the goal of developing CFRTPCs, on industrial level, using FDM with better control over volume fraction and fiber layup.
Coupling effect of strain rate and temperature on tensile damage mechanism of polyphenylene sulfide reinforced by glass fiber (PPS/GF30)
Authors: Shirinbayan Mohammadali , Fitoussi Joseph , Kheradmand Farid , Montazeri Arash , Zuo Peiyuan , Tcharkhtchi Abbas
Published: July 2020

Influence of loading temperature on the damage mechanism of polyphenylene sulfide (PPS) reinforced by glass fiber (PPS/GF30) under tension was experimentally studied from quasi-static (QS) to high strain rates. Two kinds of PPS/GF30 samples were prepared: PPS-0° and PPS-90° (correspond to fibers oriented parallel and perpendicular to the injection direction, respectively). After microscopic observation and thermomechanical characterizations by dynamic mechanical analysis, tensile tests up to failure with strain rates varying from 10−3 s−1 to 100 s−1 have been carried out at 25°C and 120°C with regard to PPS/GF30 glass transition temperature. To achieve the coupling effect of high strain rate and high temperature, a special chamber was designed to install on the servo-hydraulic machine. The results of QS tensile tests confirm the significant effect of fiber orientation and temperature on the Young’s modulus, the ultimate stress, and strain. High strain tensile test results showed that the PPS/GF30 composite is strain rate dependent at both temperatures. The results indicated that Young’s modulus remains constant by strain rate increasing at both temperatures while ultimate stress and strain are increased. No significant damage has been observed at 25°C in QS loading, whereas the macroscopic damage variable is increased to 20% at 120°C. Debonding at the fiber–matrix interface is the main damage mechanism at 120°C.
Influence of patellar implantation on the patellofemoral joint of an anatomic customised total knee replacement implant: A case study
Authors: Wang Linjie , Wang Chang Jiang
Published: July 2020

Few studies have been conducted to investigate kinematics and kinetics of the patellofemoral joint under physiological muscle forces and ankle joint loads. In this study, a preliminary design of a customised total knee implant was proposed and created. To compare the influences of different patella treatment scenarios, a dynamic knee simulation model was created with patient-specific muscle forces and ankle joint loads that are calculated from an OpenSim musculoskeletal model. The goal is to improve patellar implant-bone connection and restore patellofemoral joint mobility. Identical dynamic boundary conditions were applied on an unresurfaced patella and three different dome-shaped patellar implants. It was found that the unresurfaced patella and patellar implants resulted in different motions of patellar internal rotation and medial tilt. The size of the dome-shaped patellar implant affected the motion and loading of the patellofemoral joint. When the exposed patella bone was not fully covered by the patellar implant, the patella bone then contacted the femoral component during knee flexion. This would most likely lead to anterior knee pain and subsequent revision.
Tensed toward the collective: A Simondonian perspective on human experience in context
Authors: Wrbouschek Markus , Slunecko Thomas
Published: July 2020

In this article, we use Gilbert Simondon’s work on psychic and collective individuation in order to develop a process theoretical framework for studying human experience in context. We argue that experience should be conceptually understood as coextensive with the processual becoming of an individual human being. We further develop this by taking into account two complementary trajectories of becoming: psychic individuation and collective individuation. We will show how this can help us to understand the situatedness and collectivity of human experience.
Understanding the role of water in the aggregation of proteins and polymers in aqueous solution using near-infrared spectroscopy
Authors: Sun Yan , Ma Li , Wang Li , Zhu Xuewei , Cai Wensheng , Shao Xueguang
Published: July 2020

Water plays an important role in chemical and biological processes. For understanding the role of water in the aggregation of proteins and polymers, the variation of water structures in the process of aggregation was studied by near-infrared spectroscopy. The near-infrared spectra of the aqueous R2/wt and poly( N, N-dimethylaminoethyl methacrylate) solutions of different concentrations were measured at different temperatures. The spectral changes of the solutes and water with temperature were analyzed with the help of chemometric methods. In the aggregation of R2/wt, the water species with one hydrogen bond around the NH groups dissociate to initiate the change of the hydrogen bonding network of the hydration water, and then, the water molecules with two hydrogen bonds (S2) near the hydrophobic side chains release from the R2/wt, resulting in the formation of the ordered amyloid fibers. In the aggregation process of low concentration poly( N, N-dimethylaminoethyl methacrylate) solutions, the chains of the polymer tend to form a loose hydrophobic structure below 36°C and then aggregate into a micelle at a lower critical solution temperature of around 39°C. S2 acts as a bridge to connect the polymer chains in the loose hydrophobic structure, and the dissociation of the S2 bridge at high temperature is the reason for the formation of the micelle. For high concentration solution, however, the spectral information of S2 was not found in the aggregation, suggesting a direct formation of the micelle from the dehydrated chains.
Effect of addition of hydroxyapatite as secondary filler in CNT-reinforced polypropylene hybrid composites
Authors: Chaudhary Babulal , Panwar Vinay , Roy Tushar , Pal Kaushik
Published: July 2020

This work entails the effectiveness of hydroxyapatite (HAp) as secondary filler in polypropylene (PP) matrix composites reinforced with HAp-decorated multiwalled carbon nanotubes (MWCNTs). Different composites were prepared through the melt mixing approach. The consequent effect of typical biocompatible ceramic coating on the dispersion of CNTs in a PP matrix and thereby effect on its thermal and mechanical properties have been discussed in this research work. Isothermal hydroxylation technique has been used for the coating of HAp on MWCNTs. It has been observed from the collective information obtained from X-ray diffraction, Fourier-transform infrared spectroscopy, Raman spectroscopy and field-emission scanning electron microscopy images that HAp constitutes a new phase in the HAp-CNT nanocomposite in the form of a coating of HAp over nanotubes. As a result of which, the use of HAp-coated MWCNTs in PP improved its tensile strength by 38%, modulus of elasticity by 72%, storage modulus by 43% and ductility by around 7.4% in comparison to uncoated MWCNT-reinforced PP composite. However, the coating of HAp shows an insignificant effect for change in temperature-dependent properties of the CNT/PP composites. The improvement in mechanical properties is attributed to the interfacial compatibility between HAp and PP.
Variations on a Dance of the Roma
Authors: Howard Karen
Published: July 2020

Explore a music and dance tradition known as čoček in Macedonia, and by other names in Bulgaria. Albania, Serbia, and throughout the Balkan Peninsula. This tradition is long associated with the Roma people who carry a reputation of music virtuosity. Suggestions for using the dance and music in elementary and secondary general music classes are offered as well as options for listening.
Handedness and White Matter Networks
Authors: Budisavljevic Sanja , Castiello Umberto , Begliomini Chiara
Published: July 2020

The development and persistence of laterality is a key feature of human motor behavior, with the asymmetry of hand use being the most prominent. The idea that asymmetrical functions of the hands reflect asymmetries in terms of structural and functional brain organization has been tested many times. However, despite advances in laterality research and increased understanding of this population-level bias, the neural basis of handedness remains elusive. Recent developments in diffusion magnetic resonance imaging enabled the exploration of lateralized motor behavior also in terms of white matter and connectional neuroanatomy. Despite incomplete and partly inconsistent evidence, structural connectivity of both intrahemispheric and interhemispheric white matter seems to differ between left and right-handers. Handedness was related to asymmetry of intrahemispheric pathways important for visuomotor and visuospatial processing (superior longitudinal fasciculus), but not to projection tracts supporting motor execution (corticospinal tract). Moreover, the interindividual variability of the main commissural pathway corpus callosum seems to be associated with handedness. The review highlights the importance of exploring new avenues for the study of handedness and presents the latest state of knowledge that can be used to guide future neuroscientific and genetic research.
Brain Organoids: Tiny Mirrors of Human Neurodevelopment and Neurological Disorders
Authors: Yadav Anuradha , Seth Brashket , Chaturvedi Rajnish Kumar
Published: July 2020

Unravelling the complexity of the human brain is a challenging task. Nowadays, modern neurobiologists have developed 3D model systems called “brain organoids” to overcome the technical challenges in understanding human brain development and the limitations of animal models to study neurological diseases. Certainly like most model systems in neuroscience, brain organoids too have limitations, as these minuscule brains lack the complex neuronal circuitry required to begin the operational tasks of human brain. However, researchers are hopeful that future endeavors with these 3D brain tissues could provide mechanistic insights into the generation of circuit complexity as well as reproducible creation of different regions of the human brain. Herein, we have presented the contemporary state of brain organoids with special emphasis on their mode of generation and their utility in modelling neurological disorders, drug discovery, and clinical trials.
Violence Against Women: Representations, Interpretations, and Education
Authors: Chhabra Meenakshi , Fiore Lisa B. , Pérez-Villanueva Sonia
Published: July 2020

Cultural representations of violence against women have been mystified, eroticized, and depicted as heroic, camouflaging, and trivializing acts of violence as a societal norm for thousands of years. This themed issue invites people to re/claim identities and power, and enter into a global cultural discourse connected with cross-disciplinary channels and creative work.
Metabolic Profiling of Blood and Urine for Exploring the Functional Role of the Microbiota in Human Health
Authors: Diallo Ana F. , Lockwood Mark B. , Maki Katherine A. , Franks Alexis T. , Roy Abhrarup , Jaime-Lara Rosario , Joseph Paule V. , Henderson Wendy A. , Chung Seon Yoon , McGrath Jacqueline , Green Stefan J. , Fink Anne M.
Published: July 2020

The quantification of metabolites in blood and urine allows nurses to explore new hypotheses about the microbiome. This review summarizes findings from recent studies with a focus on how the state of the science can influence future nursing research initiatives. Metabolomics can advance nursing research by identifying physiologic/pathophysiologic processes underlying patients’ symptoms and can be useful for testing the effects of nursing interventions. To date, metabolomics has been used to study cardiovascular, respiratory, endocrine, autoimmune, and infectious conditions, with research focused on understanding the microbial metabolism of substrates resulting in circulating/excreted biomarkers such as trimethylamine N-oxide. This review provides specific recommendations for the collection of specimens and goals for future studies.
Arterial percutaneous angioplasty in hemodialysis access: Endovascular treatment of hand ischemia
Authors: Teixeira Gabriela , Almeida Paulo , Loureiro Luís , Antunes Inês , Rego Duarte , Teixeira Sérgio , Mendes Daniel , Sousa Clemente N , Queirós José , de Matos Norton , Almeida Rui
Published: July 2020

Background:

Hemodialysis access–induced distal ischemia consists of symptomatic extremity malperfusion after vascular access creation. It is usually caused by discordant vascular resistance, with arteriovenous shunting of a high blood volume from arterial into venous system and subsequent hand hypoperfusion. Less often, hemodialysis access–induced distal ischemia is caused by arterial stenosis. In these cases, access frequently has normal/low flow, radial pulse is usually absent and not recoverable with vascular access digital compression, diabetes is often present, and percutaneous transluminal angioplasty can be critical for access and limb salvage.

Methods:

Retrospective study conducted between June 2011 and February 2018 of patients with vascular access submitted to arterial percutaneous transluminal angioplasty for limb-threatening ischemia.

Results:

Twenty-nine patients were referred for arterial angiography after hemodialysis access–induced distal ischemia diagnosis and physical examination or ultrasound findings suggestive of arterial disease. In 11 patients, percutaneous transluminal angioplasty was not technically feasible. Among 18 treated patients, 83.3% had diabetes and 60% had skin ulcerations. Target arteries were radial (11), brachial (7), axillar (2), ulnar (2), and subclavian (1). Clinical success, defined as arteriovenous maintenance and wound healing/pain resolution, was observed in 12 patients (66.7%). Concomitant procedures included adjuvant banding ( n = 2) and finger amputation ( n = 1), and one reintervention was performed. No intra- or postoperative complications were reported.

Conclusion:

Hemodialysis access–induced distal ischemia is a serious complication of hemodialysis vascular access, with multifactorial etiology. Correct and timely diagnosis is crucial for maintaining access and limb salvage. Percutaneous transluminal angioplasty is a minimally invasive procedure that may be effective and long-lasting in carefully selected patients with ischemic complaints.
Dynamic stability analysis of noncircular two-lobe journal bearings with couple stress lubricant regime
Authors: Zare Mehrjardi Mahdi
Published: July 2020

In this research, the steady state and dynamic performances of two-lobe noncircular journal bearings with couple stress lubricant are presented. The lubricating oil, containing additives and contaminants, is modeled as the couple stress fluid. The modified Reynolds equation is obtained using the couple stress lubrication theory and is then solved by finite element method as an efficient numerical technique. The steady-state characteristics of bearings, including the load carrying capacity and attitude angle, are determined for various values of the couple stress parameter. The results show that applying the couple stress fluid improves the efficiency of two-lobe bearings in terms of an increased load carrying capacity and reduced attitude angle. Also, the stability performance of the investigated bearings is studied using rotor motion equations based on linear and nonlinear dynamic methods. The results indicate that any increase in the lubricant couple stress parameter enhances the bearing ability to damp the rotor perturbations. In other words, by varying the lubricant from Newtonian oil to the couple stress type and upgrading its properties, the curves of the critical mass parameter and whirl frequency ratio have an increasing and decreasing trend, respectively. Based on the fourth-order Runge–Kutta method results, the dynamic trajectory of the rotor center in the bearing space changes with increasing the couple stress parameter from diverging disturbances and limits the cycle perturbations around the bearing center to converging oscillations to the static equilibrium point. Moreover, the effect of changing lubricant properties on the two-lobe bearing’s performance is more pronounced at higher values of the couple stress parameter, especially with an increase in the noncircularity of bearings’ geometry.
Analysis of hydrostatic rough thrust bearing lubricated with Rabinowitsch fluid considering fluid inertia in supply region
Authors: Singh Udaya P , Sinha Prawal , Kumar Mukesh
Published: July 2020

With the advancement of lubrication technology, precise prediction of performance characteristics of bearings is the first and inevitable step for stability of mechanical systems. Most of the existing theoretical analyses of hydrostatic thrust bearings lubricated with non-Newtonian fluids have considered the lubricant inertia, only in the recess and land regions but did not account either for the inertia of lubricant in the supply region or the surface roughness of the bearings. This could be a cause for the deviation between the theoretical results and the experimental data under certain conditions. In this work, combined influence of surface roughness as well as lubricant inertia in the supply region, on the static properties of a hydrostatic stepped thrust bearing lubricated with a non-Newtonian fluid, has been discussed using Rabinowitsch fluid model. Surface roughness effects have been accounted for using Christensen theory of rough surfaces. It is expected that the current study could bridge the gap between the experimental and theoretical studies. Solution for momentum equation has been obtained by means of average inertia approach. Analytic expressions for film pressure have been derived for radial and circumferential roughness patterns. Mathematica 11.0 has been used for numerical computations, wherever necessary. Results for film pressure and load carrying capacity have been plotted and discussed. It is observed that the present results are in a better agreement with the experimental data.
Effects of viewing flowering plants on employees' wellbeing in an office-like environment
Authors: Elsadek Mohamed , Liu Binyi
Published: July 2020

Despite the existence of plentiful studies on how plants can positively affect human wellbeing, few have focused on the potential effects of flower colours on stressed people. The present study was designed to illustrate the psychophysiological relaxation impacts of seeing purple and blue hydrangea flowers among finance workers. Thirty employees were asked to view purple, blue flowers or an empty table for 3-min, during which we measured the participants' brain activity, heart rate variability and skin conductance. We also assessed their emotions and mood states. Findings suggest that, compared with viewing the control, viewing blue and purple flowers resulted in a significant increase in alpha relative waves in the prefrontal and occipital lobes, and a significant increase in parasympathetic nervous activity. A significant increase in the sensation vote for ‘comfort', ‘relaxation' and ‘cheerfulness', as well as a dramatic improvement in the mood state was observed. The results show clear evidence for the support of the use of blue and purple flowering plants in places where comfort and calmness are required. In addition, blue flowers were more favoured and had the greatest positive effects. Results indicate that viewing flowering plants would be a promising therapeutic approach for enhancing physiological functions and improving psychological relaxation for office workers.
COVID-19/Sociology
Authors: Connell Raewyn
Published: July 2020

Though the COVID-19 epidemic is a social disaster as much as a medical one, and though some sociological ideas circulate in public discussions, disciplinary sociology has had little influence. Internal discussions have mostly been conventional, and familiar sociological theory and methodology seem inadequate to this situation. Taking the viewpoint of the virus helps to shift perspective on a historical moment where a deadly threat is enabled by megacities, mass air travel, callous and corrupt regimes, and the undermining of public services. In this conjuncture sociology, with other social sciences, is under threat. But we can contribute to responses that mobilize community resources to deal with a social/biological crisis, and prepare for the others that will certainly come.
Non-lethal strangulation by a towrope: A complication of water tubing
Authors: J Yi Amy , Kurachek Stephen , Zagel Alicia , Posani Yogitha , Mishra Avisya , Hanson Deb , Hustad Leah , Chinnadurai Sivakumar
Published: July 2020

Water tubing accidents can result in significant morbidity and mortality, with injuries often following collisions with objects, boats, or other recreating individuals. A less frequent subgroup of these accidents is related to the towrope, which can cause severe injuries such as amputation or limb strangulation. Herein we report a case of a 14-year-old female who sustained significant airway injuries from a water tubing towrope strangulation that required a multidisciplinary approach and extensive follow-up. The resuscitation at a local hospital with a rapid sequence intubation was likely life-saving and allowed patient transfer to specialized care. This is the first published documentation of a non-lethal strangulation by water tubing towrope that underscores the importance of pre-hospital decision-making and local stabilization.
The experience of attending a farm-based day care service from the perspective of people with dementia: A qualitative study
Authors: Ibsen Tanja L , Eriksen Siren
Published: July 2020

People with dementia have different needs, and it is important to have variation in the services that are offered for this population. Farm-based day care aims to meet this diversity in need, but research on such services is lacking. The present study provides knowledge about how people with dementia experience attending farm-based day care services in Norway. Ten semi-structured interviews were conducted for five different services, while the participants were at the farm. The interviews were analysed in accordance with the content analysis of Graneheim, U., & Lundman, B. (2004) [ Nurse Education Today, 24(2), 105-112] and revealed three main categories that included (1) social relations, (2) being occupied at the farm, and (3) individually tailored service. The findings were summarised in the overall theme that attending day care at a farm makes me feel like a real participant. Our findings indicate that the farm-based day cares in the present study provide person-centred care. The farm setting facilitates services that are tailored to the individual, where the participants get to use their remaining resources and spend time outdoors. Further, farm-based day care was described as being suitable for people with or without farm experience and must be seen as an important supplement to regular day care for those who could benefit from a more active service.
‘They Really Should Start Listening to You’: The Benefits and Challenges of Co-Producing a Participatory Framework of Youth Justice Practice
Authors: Smithson Hannah , Gray Paul , Jones Anna
Published: July 2020

This article presents the findings from a pioneering project between a university and 10 regional youth justice services. The project resulted in the co-production, with young people, of a framework of principles termed ‘Participatory Youth Practice’ (PYP). The benefits and challenges of producing PYP are discussed. We argue that the framework – grounded in Article 12 of the United Nations Convention on the Rights of the Child and ‘child first, offender second’ principles – is a formative step in the process of creating a youth justice system that respects and acknowledges children and young people’s rights and enables them to meaningfully participate in decision-making processes.
Rapid postearthquake safety evaluation of buildings using sparse acceleration measurements
Authors: Tsuchimoto Koji , Narazaki Yasutaka , Hoskere Vedhus , Spencer Billie F
Published: July 2020

After a seismic event, buildings need to be inspected to confirm their safety prior to reoccupation. As such, the rapid evaluation of the condition of individual buildings is important for minimizing disruption to lives and business. However, traditional manual inspection by experts is laborious and time-consuming. Structural health monitoring provides the potential to accelerate the required evaluation. This article proposes a cost-effective approach for rapid safety evaluation of buildings after seismic events using sparse acceleration measurements. First, a damage-sensitive feature is defined that can be used to infer the condition of buildings. Herein, the maximum interstory drift angle is proposed as a reliable damage index to classify the safety of buildings after seismic events. A convolutional neural network is then employed to uncover the complex relationship between the damage-sensitive features and the building condition. A five-story steel building is considered to validate the proposed approach. First, a three-dimensional nonlinear model of the building is created. To generate the required training data, a simplified nonlinear model is developed, along with a corresponding linear model, as use of the three-dimensional model is too computationally expensive. The training data for the convolutional neural network incorporates uncertainties in both the analysis model and the ground motion. Initial evaluation is conducted using the simplified nonlinear model, while final validation of the proposed approach is performed using the results of the three-dimensional nonlinear analysis model subjected to historical earthquakes. The results demonstrate the ability of the proposed approach to accommodate differences between the in-situ structure and the analysis model, as well as the efficacy of this approach for rapid postearthquake safety evaluation of buildings.
Efficacy of Next-Generation EGFR-TKIs in Patients With Non-Small Cell Lung Cancer: A Meta-Analysis of Randomized Controlled Trials
Authors: Qi Yi-Tian , Hou Yi , Qi Liang-Chen
Published: July 2020

Background:

The efficacy of next-generation epidermal growth factor receptor-tyrosine kinase inhibitors in patients with advanced non-small cell lung cancer who have failed first-generation epidermal growth factor receptor-tyrosine kinase inhibitors still remains under investigation.

Objective:

The aim of this meta-analysis was to systematically assess the efficacy and safety profiles of next-generation epidermal growth factor receptor-tyrosine kinase inhibitors in patients with advanced non-small cell lung cancer who failed first-generation epidermal growth factor receptor-tyrosine kinase inhibitors.

Methods:

We performed a comprehensive search of several electronic databases up to September 2018 to identify clinical trials. The primary end point was overall survival, progression-free survival, disease controlled rate, objective response rate, and adverse events. Epidermal growth factor receptor-tyrosine kinase inhibitor emergent severe adverse events (grade ≥ 3) were analyzed. Odds ratio along with 95% confidence interval were utilized for main outcome analysis.

Results:

In total, we had 3 randomized controlled trials in this analysis. The group of next-generation epidermal growth factor receptor-tyrosine kinase inhibitors had significantly improved progression-free survival (odds ratio = 0.34, 95% confidence interval = 0.29-0.40, P < .00001), as well as objective response rate (odds ratio = 10.48, 95% confidence interval = 3.87-28.34, P < .00001) and disease controlled rate (odds ratio = 6.03, 95% confidence interval = 4.41-8.25, P < .00001). However, there was no significant difference in overall survival with next-generation epidermal growth factor receptor-tyrosine kinase inhibitors (odds ratio = 1.05, 95% confidence interval = 0.85-1.31, P = .66). Meanwhile, the odds ratio for treatment-emergent severe adverse events (diarrhea, rash/acne, nausea, vomiting, anemia) between patients who received next-generation epidermal growth factor receptor-tyrosine kinase inhibitors and those who received first-generation epidermal growth factor receptor-tyrosine kinase inhibitors did not show safety benefit ( P > .05).

Conclusions:

Next-generation epidermal growth factor receptor-tyrosine kinase inhibitors were shown to be the better agent to achieve higher response rate and longer progression-free survival in patients with non-small cell lung cancer as the later-line therapy for previously treated patients with first-generation epidermal growth factor receptor-tyrosine kinase inhibitors. Meanwhile, they did not achieve benefit in overall survival and safety compared with the chemotherapy group. Further research is needed to develop a database of all EGFR mutations and their individual impacts on the various treatments.
Persistent second cervical intersegmental artery in a case of possible PHACE syndrome
Authors: Gailloud Philippe
Published: July 2020

The proximal segment of the vertebral artery most often consists of a persistent sixth cervical intersegmental artery that originates from the subclavian artery, but it may also derive from a fifth, fourth, or third cervical intersegmental artery (in decreasing order of frequency), or from a first thoracic intersegmental artery. The involvement of more cranial cervical branches is exceptional, with no known persistent first cervical intersegmental artery and possibly five cases of persistent second cervical intersegmental arteries reported so far. This report describes a patient with multiple arterial variations including right persistent second cervical intersegmental artery of common carotid origin, distal VA duplication, circumflex aortic arch, and segmental internal carotid agenesis in a context of possible PHACE syndrome.
Treatment of cerebral vasospasm secondary to subarachnoid hemorrhage utilizing the Comaneci device
Authors: Badger Clint A , Jankowitz Brian T , Shaikh Hamza A
Published: July 2020

Delayed cerebral ischemia due to vasospasm following subarachnoid hemorrhage continues to have high morbidity and mortality despite current treatments. This report highlights the use of the Comaneci (Rapid Medical, Yokneam, Israel), a device FDA approved for temporary coil embolization assistance, for the treatment of symptomatic vasospasm. Ten days post subarachnoid hemorrhage, a patient developed acute left-sided hemiparesis with angiographic vasospasm. Through a Headway 17 microcatheter, a Comaneci 17 was deployed in the right ICA terminus, M1, M2, A1, and, A2 segments resulting in improvement of angiographic vasospasm and the patient’s left-sided hemiparesis. On the following day, a repeat angiogram demonstrated no recurrence of vasospasm. The patient had complete return on neurologic function by post bleed day 18 continuing to her four-week follow-up appointment. This case demonstrates the feasibility of the Comaneci device as an effective tool in the treatment of vasospasm following subarachnoid hemorrhage.
Application of fiber-reinforced concrete lining for fault-crossing tunnels in meizoseismal area to improving seismic performance
Authors: An Dong , Chen Zheng , Meng Linghan , Cui Guangyao
Published: July 2020

The fault-crossing tunnel in meizoseismal area is directly subjected to strong ground motion, which leads to the failure of the tunnel lining. In order to improve the seismic safety of tunnel, fiber-reinforced concrete is applied to tunnel lining in this article. Taking the section of Zhongyi tunnel crossing Wanlong fault as an example, seismic performance of fiber-reinforced concrete tunnel lining was studied by finite difference numerical calculation software FLAC3D. The seismic displacement, stress response, and side wall convergence of secondary lining structures which are plain concrete, steel fiber-reinforced concrete, and steel-basalt hybrid fiber-reinforced concrete were comparatively analyzed. Moreover, the safety factor of each lining structure was investigated with the present numerical model. With the obtained data, seismic performance of steel-basalt hybrid fiber-reinforced concrete secondary lining is better than that of steel fiber-reinforced concrete secondary lining. The results may provide references for seismic design of fault-crossing tunnels in meizoseismal area.
Numerical buckling analysis of cracked Bi-material thin plates
Authors: Ould Hamouda Sara , Tani Nabil Kazi , Tamine Tawfik
Published: July 2020

The aim of this present study is to analyze numerically the buckling behavior of cracked thin bi-material structures subjected to compression and tensile stresses and this, by considering the evolution of crack lengths and its orientations at the interface. This research work allows to quantify numerically the buckling phenomenon which can affects the thin plates for both cases, with and without interface crack especially, when the plate is subjected to tensile loading. The main important results of numerical simulations show that for the case of compression loading, the presence of interfacial crack increases significantly the strength of the thin plate against buckling phenomena. In the other hand, thin crack plates buckling is more pronounced when the crack tip is close to the interface (θ = 90°, θ = 75°). Finally, unlike to the case of homogeneous thin plates, the incorporation of bi-material aspect in thin plates design offers more strength against buckling either for compression or tensile loading.
Study on a high-speed oil-free pump with fluid hydrodynamic lubrication
Authors: Fang Xufeng , Hou Yu , Cai Yijie , Chen Liang , Lai Tianwei , Chen Shuangtao
Published: July 2020

A novel centrifugal pump with axial directional inlet and outlet flow was presented. The system fluid was employed as the lubricant for the hydrodynamic bearings by which the pump can operate at the maximum speed of 8100 r/min without oil lubrication or rigid support. The performance curves related to the efficiency, head, and volume flow rate were obtained via a water cycle test rig. The efficiency at best efficiency point reached 36.14% with a volume flow rate of 4.13 m3/h and a head of 27.34 m at 7800 r/min. The maximum head reached 37.28 m, with a volume flow rate of 0.568 m3/h at 7800 r/min. The maximum volume flow rate of 6.05 m3/h was obtained with a head of 19.45 m at 8100 r/min. Then, the three-dimension computational fluid dynamics model with Reynolds-averaged Navier–Stokes equations and shear stress transport k- ω turbulence model for the pump and bearings was set up individually. The numerical results agreed well with the experimental data.
Recontextualising race, politics and inequality in transnational knowledge circulation: Biographical resignifications
Authors: Windle Joel
Published: July 2020

This article examines shifts in the meaning and relevance of institutionalised knowledge about social inequalities as it circulates globally. In so doing, it contributes to research critiquing an unequal geopolitics of knowledge that grants greatest authority to theories produced in the global north (Connell, 2007; Mignolo, 2003). I discuss the resignification of globally circulating texts in terms of their entextualisation and reflect on my own role in this process through an auto-ethnographic narrative. I focus on two widely circulating texts that explicitly deal with questions of social power and globalisation: ‘On the cunning of imperialist reason’ (Bourdieu and Wacquant, 1999) and ‘A pedagogy of multiliteracies’ (The New London Group, 1996). Examination of their re-entextualisation in Brazil points to the need to bring to bear additional epistemological resources attuned to social and political struggles in order to address the racial inequalities that have come to be at the forefront of my own scholarly concerns. The article concludes by suggesting ways of engaging with globally circulating knowledge through the incorporation of knowledge produced by local struggles and emerging from everyday categories, giving the example of possible uses of the Brazilian concept of gambiarra.
Performance characteristics of top-level youth judokas in light- and heavy-weight categories
Authors: Engwerda Ingrid M , Lidor Ronnie , Elferink-Gemser Marije T
Published: July 2020

Professionals involved in training programs for judokas should have access to evidence-based data on various characteristics of these athletes. In the current study, anthropometric (e.g., body height, body mass), physiological (e.g., power based on vertical jump height, maximal handgrip strength), and psychological (e.g., athletic coping skills) characteristics of judokas were examined. The judokas, aged 16-21, were classified into two groups: 30 light weight (males = 19, females = 11) and 27 heavy weight (males = 13, females = 14). Four MANCOVAs separated by sex were performed on the anthropometric, physiological, and psychological data. A discriminant analysis was also carried out. Results showed that heavy-weight males outscored their lighter peers on body height ( d = 1.88), arm span ( d = 1.88), and maximal handgrip strength. In the females, light-weight judokas outscored their heavier peers on jumping ability ( d = 1.02) and peak power bench press ( d = 1.20). Female heavy-weight judokas had greater body height ( d = 1.46), a longer arm span ( d = 1.35), and higher scores on maximal handgrip strength than light-weight judokas. The discriminant analysis revealed that 87.5% and 84.0% of the original grouped male and female judokas, respectively, were correctly classified. No differences in coping skills or self-regulation of learning between categories were observed. It is recommended that professionals involved in training programs may consider these differences in data when developing training programs for young judokas.
Paulo Freire’s role and influence on the praxis of popular communication in Brazil
Authors: Peruzzo Cicilia MK
Published: July 2020

The article approaches the relationship between the aims of Paulo Freire’s education for liberation and the praxis of popular communication in Brazil. The goal is to understand the extent to which aspects of Freire’s thoughts can intersperse with concepts and practices of popular, community, and alternative communication in Brazil. The study is based on bibliographic research on Freire’s work while reflecting on some of the principles of the education for liberation, particularly those embedding the praxis of popular communication in social movements. This paper concludes by arguing that principles such as ‘communication as dialogue’, ‘critical consciousness’, the ability to become a ‘subject’, ‘education as a practice for freedom’, ‘connection to reality’, and ‘social transformation’ lie prominently in the concept and practices of popular and community communication.
Follow Me Too: Determinants of Transitive Tie Formation on Twitter
Authors: Malik Parul , Lee Seungyoon
Published: July 2020

Transitivity, defined as the tendency for node A to be connected to node B given that A is connected to node X and X is connected to B, has been found to be a strong predictor of tie formation in various types of social networks. As transitive ties can influence information sharing, diffusion, and attitudes toward messages, understanding the motivations and mechanisms behind transitive tie formation in online social networks (OSNs) is important. Using a large longitudinal dataset from a popular OSN, Twitter, we examine the factors affecting transitivity. Results show that the strength of ties, activity like the number of tweets, and most importantly, the number of common connections are key factors affecting transitive tie formation. Theoretical implications regarding the evolution of network structure and polarization of views as well as practical suggestions for organizations aiming to accumulate followers for information sharing are discussed.