bluuebunny/crossref_metadata_2025 huggingface dataset:
Changes in Cognition Functions and Depression Severity After Bariatric Surgery: A 3-Month Follow-up Study
Authors: Ahmadzad-Asl Masoud , Dinarvand Bita , Bodaghi Fatemeh , Shariat Seyed Vahid , Sabzvari Zainab , Talebi Mina , Shariati Behnoush , Pazouki Abdolreza , Shariati Behnam
Published: June 2022

Background: Changes in cognitive profile, such as memory and other functions in patients with morbid obesity after bariatric surgery have been reported in the literature with inconsistent results. Objectives: This study aimed to evaluate cognitive changes, executive function and depression severity before and after bariatric surgery in patients with morbid obesity. Methods: In this prospective cohort study, 70 patients with morbid obesity (40 patients undergoing bariatric surgery and 30 patients in the waiting list) referred to the Rasool Akram Medical Complex, obesity clinic, Tehran, Iran, in 2016 entered the study. The two groups were assessed using the Wechsler Memory Scale (WMS) (consists of 7 subscales and assesses memory), the Wisconsin Cart Sorting test (WCST) (includes 64 cards and assesses cognitive skills), the Hamilton Depression Scale (HAM-D) (for measuring depression) and bariatric analysis and reporting outcome system (BAROS) questionnaire (scale to report of the therapeutic results of bariatric surgery and including the three criteria of the weight loss percentage, the change in health state, and the quality of life) at the beginning of the study and three months after the surgery. Moreover, the Bariatric Analysis and reporting outcome system (BAROS) questionnaire was filled three months after surgery. Results: The average changes in WMS score (P = 0.043), working memory (P = 0.002), HAM-A (P = 0.032), weight, and BMI (P = 0.0001) in the surgery group were significantly higher than the control group. There was a significant positive correlation between change in the number of preservative errors in WCST within the surgery group with BAROS score (P = 0.004). Moreover, there was a significant correlation between changes in the score of WMS and those in BMI in the surgery group. Conclusions: Bariatric surgery is associated with improvements in some cognitive functions and worsening of depressive scores in patients with morbid obesity.
The Revived Statehood (1918–21) in the Reflection of the Czech (Slovak) and Polish Post Stamps and the Didactic Applications
Authors: Štěpánek Kamil
Published: June 2022

The text analyses the historical, didactic and methodological aspects of the use of post stamps in the educational process. It focuses on the reflection of the renewed Czechoslovak and Polish statehood after the end of the First World War through the period and jubilee post stamps. Like posters, post stamps are a historical source reflecting mainly modern (national) history and, for example, the changes in the statehood. On the basis of an appropriate selection, the mechanisms of legitimization of the state power or propaganda can be concisely and effectively explained in history lessons. The described procedure creates an fective alternative educational medium that strengthens the interdisciplinary cooperation of school history –media education.
Czechoslovaks and Poles in Royal Air Force During the Battle of Britain
Authors: Binar Aleš
Published: June 2022

The study deals with the involvement of foreign pilots in the Battle of Britain, both Czechoslovaks and Poles. Until now, there have been number of studies and monographies describing the formation and deployment of Czechoslovak and Pole pilots. Yet there has been no comparison of both sides. That is why this study focuses on a comparison of the legal status of Czechoslovak and Polish air force units, as well as their numbers, formations, and their structure. Using this approach, the aim is to answer in which aspects there were similarities and in which there were differences, thus, to set the phenomenon of Czechoslovak and Polish pilots in the RAF within a mutual context.
Paleographical Analysis of Scribes’ Hands in the Boskovice Land Register inv. no. 44
Authors: Sedláček Petr
Published: June 2022

The study deals with the land register of the town of Boskovice, inventory no. 44 (1784–1790), from the paleographic point of view. It especially focuses on the handwriting identification of the scribes that participated in its functioning in the 18th century. In addition to elementary questions about determining the style of writing and the way of using abbreviations, it tries to observe possible integration of humanistic elements into neo-Gothic cursive (“Kurrent”).
Civil Defence Subject Matter Education in the Former Czechoslovakia in the 1918–1939 Period
Authors: Kavan Štěpán , Oulehlová Alena
Published: June 2022

Activity of both the individual and the society has been directed towards creation of values essential for their life since ancient times, either for their protection against harmful impacts of natural and anthropogenic phenomena, or a combination thereof. The aim of the research presented in the article is to examine conditions and education development in the civil defence subject matter in the former Czechoslovakia in the 1918–1939 period. The performed research was carried out as a systematic study of socio-educational phenomena in order to obtain knowledge that describes and explains historical approach to civil defence education. The research part included a systematic process of gathering information, synthesizing the already existing knowledge and its structuring and sorting. A system approach to scientific literature research was used in order to obtain available information sources, published results as well as information from the field of education and civil defence education. The results show that the need for civil defence education was seen as an integral part of the education of a conscious, sturdy, disciplined and prepared citizen. Emphasis in school education and training was put mainly on moral awareness, physical fitness and civil defence training.
An Outline of the Teaching Profession in the History of the Polish Nation
Authors: Kuźniewska Zofia Hanna
Published: June 2022

The teaching profession is one of the oldest in the history of mankind and plays a very important role in society. A teacher’s education and duties varied throughout history. In Poland, the process of shaping the teaching profession began with the establishment of the first parish schools in the 11th century. Since then, both the schools and the teacher were fully subordinate to the Church. The teaching profession developed slowly from the time of obtaining qualifications in parish schools until the present day, when education can be acquired in teacher training colleges or universities.
Thinking in Crisis: Towards an Ethics of Speculation?
Authors: Duvernoy Russell J. ,   International Association for Environmental Philosophy
Published: June 2022

The paper critically explores tensions inherent in speculative thinking in the context of climate change. It argues that speculative thinking is not a supererogatory luxury or idle pastime, but rather an essential necessity, especially in the context of climate change. Understanding this requires becoming more aware of operative tensions of speculative practice. In particular, the paper focusses on how climate discourses intersect and engage our variable affective economies through the affect of fear and proposes two practical virtues (“speculative courage” and “contemplative attending”) to be cultivated towards a responsible practice of speculative thought in this context.
Enhanced dehydroepiandrosterone levels are positively correlated with N3 sleep stage in long-term mindfulness meditation practitioners
Authors: Nagendra Ravindra P. , Sathyaprabha Talakad N. , Kutty Bindu M.
Published: June 2022

Objectives Meditation practices positively influence the neural, hormonal and autonomic systems. We have demonstrated that long-term practice of mindfulness meditation increases N3 and rapid eye movement (REM) sleep stages and bring efficient autonomic modulation during sleep. In the present study, the probable humoral correlation that could bring about these changes is evaluated.

Material and Methods Long-term Vipassana meditators (n=41) and controls (n=24) (males, 30-60 years of age) underwent a two-day consecutive whole night polysomnography recording. During the second day, with exposure to 100Lux brightness, blood was sampled from the antecubital vein between 8-9 PM and in subsequent early morning. Sleep stage was scored as per American Society of Sleep Medicine (ASSM) guidelines for the second-day recording. Sleep-related hormones were estimated - melatonin by radioimmunoassay; dehydroepiandrosterone (DHEA), cortisol, growth hormone (GH) and prolactin with enzyme-linked immunosorbent assay (ELISA); DHEA/cortisol ratio was calculated. Percentage of sleep stages and hormonal levels were compared between both groups using independent ‘t’ test and Pearson’s correlation was estimated between sleep stages and hormonal levels.

Results Meditators showed increased N3, REM sleep stages. Though evening cortisol was comparable between the two groups; early morning cortisol, diurnal DHEA and melatonin were significantly higher in meditators. Diurnal DHEA correlated significantly with the N3 sleep stage in meditators.

Discussion Higher diurnal DHEA despite variations in corresponding cortisol in meditators demonstrates that long-term Vipassana meditation practice modulates the hypothalamicpituitary-adrenal (HPA) axis and thereby influences sleep. Thus, the study provides evidence to explore the mechanism most likely involved with mindfulness meditation intervention in insomnia.
Central sleep apnea in a treatment-resistant migraine patient: a case report
Authors: Parsapour Zahra , Torabi Erfan , Amirifard Hamed , Emami Leila
Published: June 2022

Introduction Patients with migraine, who suffer from sleep apnea, whether obstructive or central, might lead to treatment-resistant headaches. In this study, we have reported a 42-year-old man with a confirmed treatment-resistant migraine headaches and hemiplegic attacks, who was referred to our sleep clinic for evaluation of sleep breathing problems.

Case Report The patient had recurrent attacks of migraine headaches with hemiplegic attacks. The patient had headache in the past 15 years that based on ICHD-3 criteria classified as hemiplegic migraine. The severity and recurrences of headache and hemiplegic attacks gradually increased for 1 year, before he referred to our sleep clinic that led to several hospital admissions. He had been evaluated for other causes of headache; it seems that other headache causes have been ruled out. Treatment with medication was not effective to abolish symptoms. He had a history of occasional snoring and his wife had witnessed multiple episodes of apnea and frequent awakening by feeling suffocation at sleep. The patient abused methadone since 2 years ago. Based on the findings in polysomnography, the patient was diagnosed with central sleep apneas. After titration, bi-level positive airway pressurespontaneous timed mode (BiPAP-ST) was prescribed for the patient. In one year of using BiPAPST the central apneas events were controlled, while the frequency of migraine headache decreased remarkably to one attack per month and the hemiplegic attacks resolved without any other change in his medical treatment or methadone use.

Discussion Patients with chronic headaches usually have insufficient sleep, sleep apnea and poor sleep quality, change in sleep architecture can be an introduced trigger for headache, furthermore in opium abusers, symptoms got intensified. Resolve exacerbating factors can reduce headache recurrence and severity.

Conclusion It is important to screen high-risk patients for possible sleep disorders such as apnea, especially in treatment resistant migraine cases. Also, we should assess analgesics or opioids abuses and a complete history for other risk factors of central sleep apnea.
The secret of the London contract from 1915
Authors: Nadoveza Branko
Published: June 2022

The Treaty of London of April 1915 was primarily provided for an expansion of Italy and its access to the Entente and a break with the Central Powers. The Treaty of London did not mention the creation of a "Greater Serbia", but what Italy will gain and what will remain for Serbia and Yugoslavian peoples within Austria-Hungary. Bulgaria and its compensations in Macedonia are especially included in that agreement, to the detriment of Serbia. The Treaty of London was secret and was therefore rejected in Versailles. Its ideas were only partially realized. It was an important military, political and moral issue. The ideas of the Treaty of London were a subject of speculation.
Emergency remote teaching during the pandemics at tertiary level: Student's perceptions
Authors: Kulić Danijela , Janković Anita
Published: June 2022

The paper explores students' perceptions of the new learning model imposed on them from March to September 2020 due to the COVID-19 pandemic. This study aims to map students' cognitive attitudes towards emergency remote teaching (ERT) in order to draw relevant conclusions about whether this practice has been successful in overcoming objective obstacles. Namely, the authors are tasked with exploring the student perspective of a new academic reality and with recording how and how well the students have adapted to ERT. For the purposes of the cross-sectional study, the authors selected three faculties of the University of Priština in Kosovska Mitrovica: the Faculty of Philosophy, the Faculty of Arts, and the Faculty of Medicine. Data are collected by means of a survey, while the respondents are selected by the method of convenient sampling. The results of the study are used to improve teaching practice as well as to assess the readiness of the higher education institution to respond to emergencies in order to maintain the integrity and continuity of the teaching process.
Influence of Vojislav Bakic (PhD) on the development of the scientific pedagogy in Serbia in XIX and XX century
Authors: Rajčević Petar , Minić Vesna
Published: June 2022

Vojislav (Vuk) Bakić was born in Kordun, in the village of Perna in 1847. At that time his place of birth was in the space never precisely defined by a consistent border between Kordun and Banija as a part of Vojna Krajina which was then and a few decades later still under the direct jurisdiction of Vienna. That is how he had an early opportunity to learn German language. That fact together with his natural talents and other opportunities gave him a chance to improve his studies in Leipzig and Heidelberg. He received his PhD in Leipzig. Apart from professional literature in German, Bakić regularly used literature in French, English and Italian language. He also spoke Latin and Czech. He followed closely development of education in Serbia, surrounding countries and Europe in general. His pedagogical work took place in times when pedagogy and psychology were separating from philosophy. In that time, system of education was established as a part of modern social system. That is why the work of Vojislav Bakić must be regarded in the context of history of pedagogical science in Serbia, and at a lower level as an impact on the development of pedagogy as a science in Serbia in those times. He is an extraordinarily prolific writer of valuable pedagogical works. He was considered a pioneer in a number of pedagogical disciplines within the pedagogical science. He advocated for the high education of secondary school teachers in Serbia. He turned pedagogy into a university discipline. He organized studies of pedagogy in Serbia at the European level at the time.
Traditional culture in the first cycle of basic education in the Republic of Serbia
Authors: Sekulić Bojana
Published: June 2022

This paper presents the results of the analysis of the content related to the knowledge of traditional culture in the current curricula for the first cycle of primary education. Primary education in the Republic of Serbia is divided into two cycles with four grades each. In the first cycle there is class teaching, and in the second there is subject teaching. This analysis includes curricula, as well as their amendments, in the period from 2004 to the end of 2021. In these amendments, the contents of traditional culture have been constantly in various stages of change, adapting to changes in the ruling system of social values, the processes of interculturalism and globalization. The main starting point in this paper, which was confirmed after the research, is that in the curricula can be identified content related to knowledge of traditional culture, such as: language, values, moral principles, customs, folklore, beliefs, myths, legends, rituals and ceremonies. These contents are especially represented in the following subjects: Serbian language, Music culture, Religious education, Folk tradition and Mother tongue with elements of national culture, and then to a lesser extent in other subjects, such as: The world around us (first and second grade), Nature and Society (third and fourth grade), Art Culture and Physical Education. The goals of teaching in these subjects are mainly: acquiring knowledge of folk traditions, preserving national and religious identity, nurturing the traditions and culture of Serbian and other peoples living in the Republic of Serbia, adopting the spiritual values of the church or community to which they historically belong and developing interculturality. The importance of traditional culture in the curriculum for the first cycle of primary education is great, because through them students gain knowledge about the cultural and spiritual values of the community to which they belong and, at the same time, strengthen their personal, ethnic, religious and national identity. identities.
Strict penalty policy: Challenges of international criminal law in crime prevention
Authors: Igrački Jasmina
Published: June 2022

At the end of the 1980s, it was realized that the policy of punishment and institutions such as prisons were in a serious crisis, and that punishment did not achieve the proclaimed goals. The repressive concept of punishment has traditionally been resorted to, and it is still present in practice in most developed countries in the world. The application of a stricter concept of crime response did not significantly change the growth trend of crime; on the contrary, such an approach increased the number of prisoners to unsustainable limits for prison institutions. Starting from the effects of imprisonment, in particular long prison sentences and life sentences and the consequences of imprisonment, there are growing calls to limit or altogether avoid imprisonment, as its shortcomings are very serious and affect both the prisoner's personality and the society. As a result of more severe punishment, there was an increase in the imposition of life imprisonment. According to available data, about half a million people in the world are serving life sentences. Life imprisonment is imposed in 183 out of 216 countries and territories, and between 2004 and 2015 there was an increase in the imposition of this sentence by about 84%. It is certainly necessary, in the coming period, to find a balanced penal policy and, wherever possible, to impose alternative sanctions because of the negative impact and very visible negative consequences that imprisonment leaves.
Objective indicators of quality of life in people with different visual status
Authors: Stanimirov Ksenija , Jablan Branka , Mijatović Luka , Grbović Aleksandra
Published: June 2022

Quality of life is a broad and complex construct. World Health Organization refers to it as an "individual's perception of their position in life (…) in relation to their goals, expectations, standards, and concerns". Reduced visual functions have a negative impact on the overall individual's functioning. Difficulties in accessing visual information and problems in orientation and mobility create significant limitations in performing daily activities and lead to diminished opportunities for education, work, social participation, and leisure. Limited participation in the aforementioned areas with lower social interactions have a negative impact on the individual's quality of life. However, it is unclear whether this construct of people with visual impairment is compromised due to reduced ability to perform daily activities or due to difficulties in establishing social interactions. Objectives. In an effort to indicate the consequences of visual impairment on quality of life, the goal of this research was to determine the objective quality of life in adults with different visual status when controlling the age. Methods. The Comprehensive Quality of Life Scale was used to evaluate the quality of life. The sample consisted of 175 people - 92 participants with visual impairment and 83 participants without structural or functional problems in the visual system. Results. Results of eight one-way ANCOVAs indicated a significant effect of visual status on Objective quality of life in total (p < .001) and on its four domains: Material well-being, Health, Productivity, Place in Community. Conclusion. The effects of different visual status on the observed construct revealed when age as a variable is controlled.
Family and friends' expected support to parents of children with disabilities
Authors: Vučinić Vesna , Martać Valentina , Anđelković Marija
Published: June 2022

Informal and formal support to parents of children with disabilities affects family functioning and life satisfaction of family members in many ways. Objective. The aim of this research was to determine the extent to which parents of children with disabilities expected support of their family and friends. Methods. The sample included 65 parents of children with disabilities, most of whom were mothers (N = 62, P = 95.4%). The Social Support Behaviors - SS-B scale (Vaux et al., 1987) was used to examine the expected support of family and friends. Results. Descriptive statistics showed that parents counted on family members' support much more than on their friends' support. Parents of children with multiple disabilities, unemployed parents, and those who lived in rural areas had lower expectations regarding family and friends' support compared to other groups. Their expectations were the lowest in the segments of financial and physical support. Conclusion. Extended family members were expected to provide greater help in all five support dimensions (emotional, social, physical, financial, and counselling). The analysis of individual items within these dimensions indicates the existence of various expectation levels within the same dimension, which is the result of specific requirements.
Computational Simulations of Wide-Beam Air-Cavity Hull in Waves
Authors: Matveev Konstantin I.
Published: June 2022

An effective method to reduce ship drag is to supply air under specially profiled bottom with the purpose to decrease the wetted surface area of the hull and thus its water resistance. Although such systems have been installed on some vessels, the broad implementation of this technique has not yet occurred. A major problem is how to sustain air lubrication in rough water. Modeling of air-ventilated flows is challenging, but modern computational fluid dynamics tools can provide valuable insight. In this study, a wide-beam, shallow-draft hull with a bottom air cavity is considered. This hull imitates a semiplaning boat that can be used for fast transportation of cargo from large marine vessels to shallow shores. To simulate fluid flow around this hull in calm water and head waves, as well as heave and pitch motions of the boat, CFD (computational fluid dynamics) software Star-CCMþ has been employed. It is found that the air cavity effectiveness decreases in waves; vertical accelerations exhibit high-frequency oscillations; and heave, pitch, and vertical accelerations increase, while time-averaged heave, pitch, and added drag show nonmonotonic behavior with increasing wave amplitude. The air-cavity hull also demonstrates substantially lower vertical accelerations in waves in comparison with a similar solid hull without bottom recess. Time histories of kinematic parameters and distributions of flow field variables presented in this article can be insightful for developers of air-cavity hulls.

Introduction

The development of systems that can lead to ship fuel savings, accompanied by the decrease in pollutant emissions, is a part of global sustainability efforts in the maritime engineering industry. Reducing the hydrodynamic drag of marine vessels can effectively address this goal. One of the methods that was proposed over a century ago but only recently started to appear on ships involves air injection under hull bottoms (Butuzov et al. 1981; Latorre 1997; Dern et al. 2015; Pavlov et al. 2020). Among several air-based methods, the formation of continuous air cavities attracted significant attention in the past and is addressed in this article. A concept of a hull with an air cavity formed inside a bottom recess is shown in Fig. 1.
The Kidney in Heart Transplantation, Tale of a Journey
Authors: Belziti César
Published: June 2022

The aim of this update is to highlight the relationship between the heart and the kidney throughout the entire journey involved in heart transplantation. Faced with heart transplantation, the cardiovascular and renal systems behave as mates of a journey that, at times, is difficult to determine when it starts, and that forces them to overcome different obstacles, such as hemodynamic changes, neuro-humoral and inflammatory response, surgical injury, immune reaction, and drug toxicity. This relationship can be seen as an adventure that they must inevitably share. We will try to accompany both organs in this journey, but paying special attention to the kidney, and to describe the associations and protection and damage mechanisms generated throughout its course. In this journey we can recognize solidarity responses to maintain the balance between both systems, but in this attempt to protect, collateral injury occurs.
Detection of Fibrosis in Cine Magnetic Resonance Images Using Artificial Intelligence Techniques
Authors: Curiale Ariel H. , Cabrera Facundo , Jimenez Pablo , Medus Jorgelina , Mato Germán , Calandrelli Matías
Published: June 2022

Background: Artificial intelligence techniques have demonstrated great potential in cardiology, especially to detect imperceptible patterns for the human eye. In this sense, these techniques seem to be adequate to identify patterns in the myocardial texture which could lead to characterize and quantify fibrosis. Purpose: The aim of this study was to postulate a new artificial intelligence method to identify fibrosis in cine cardiac magnetic resonance (CMR) imaging. Methods: A retrospective observational study was carried out in a population of 75 subjects from a clinical center of San Carlos de Bariloche. The proposed method analyzes the myocardial texture in cine CMR images using a convolutional neural network to determine local myocardial tissue damage. Results: An accuracy of 89% for quantifying local tissue damage was observed for the validation data set and 70% for the test set. In addition, the qualitative analysis showed a high spatial correlation in lesion location. Conclusions: The postulated method enables to spatially identify fibrosis using only the information from cine nuclear magnetic resonance studies, demonstrating the potential of this technique to quantify myocardial viability in the future or to study the lesions etiology
Frequency of Utilization of ICT Tools by Krishi Vigyan Kendra Scientists of Rajasthan State, India
Authors: Dashora Poorva , Henry Chitra
Published: June 2022

Information communication technology (ICT) is a multidimensional term for information technology (IT) that addresses the role of integrated communication and the integration of telecommunications (telephone lines and wireless signals) and computers as well as essential enterprise software, middleware, storage, communication which enable users to access, store, transmit and manipulate information. ICT’s is emerging as an important tool for the progress of society. The new technology has significantly improved lifestyle and efficiency levels in all sectors of the economy. This enables the utility of information & communication technology to overcome physical distances and time gaps in communication. Rapid improvements in information technology have increased their cost and space requirements, speed and storage capacity in a short span of time with traditional communication materials such as posters, charts, leaflets, folders, bulletins, audio tapes, transparency, photographs, prepared slides, videotape etc. In simple terms, ICT is a set of techniques evolved to manage information and move it from one place to another. It has been observed that in this traditional system used to take a lot of time to convey the information given to the farmers and the information was not received correctly. The rapid development of information technology has given a new look to communication systems. Now connecting two computers across the country has become an easy task. Separate ICT projects have been initiated by government, NGO’s and private companies. As a result, villages in many parts of the country have been connected through a wired network to eliminate the distance between rural and urban people. Krishi Vigyan Kendra are established by Indian Council Of Agricultural Research (ICAR) all over the country as an institutional innovation for application of agricultural science and technology on the farmer’s field with the help of multidisciplinary team i.e. Senior Scientists and Subject Matter Specialists. Who give skill or knowledge oriented training to farmers in multidisciplinary areas like Horticulture, Animal Husbandry and Fisheries, Home Science Agriculture Extension, Agronomy, Plant Protection Entomology/Pathology and Agriculture Engineer. The result of the study depict that the frequency of utilization of ICT tools by scientists for the farmers the tool which is utilized maximum by the KVK scientist is Smart phone, Internet and WhatsApp with (x = 5.00) and Rank-I and the minimum utilized by scientists Agri Guru, Mahadhan App, Agro medix agriculture app, Farm Key were not very frequently used ICT tools with (x= 0.21, 0.17., 0.7,.0.00). Rank L,LI,LII.LIII,LIV.
Utility of Platelet Derived Microparticles in Predicting Complications of Diabetes Mellitus
Authors: Sanyal Kaninika , Wadhwa Shagun , Kotru Mrinalini , Gupta Richa , Raizada Alpana , Pathak Rajesh
Published: June 2022

Background: The long term complications related to DM are the main cause of mortality and morbidity in DM. However, many of the Diabetes related complications are detected later at end stage. Thus, there is a need for early diagnosis of the complications and biomarker that predicts the outcome of the disease and its complications. PMPs are the recent particles of interest that play a major role in pathophysiology of the disease and can be used to detect complications earlier.

Aim: To study the role of PMPs in DM

Objectives: To compare the levels of PMPs in adults who are Diabetics and in complicated diabetes

Material and Methods: A prospective case control study was done in Department of Pathology and Department of Medicine. 30 Diabetic patients were taken as cases while 30 healthy adults were taken as controls. Complete hematological profile was done for both the groups. Immunophenotyping using antibodies like CD45, CD41, CD61 and Annexin V+ was used to distinguish PMPs from platelets. The annexin V + particles were identified first and separately gated which were then observed in the CD41 vs CD 61 plots. The particles that were annexin V +, CD41+, CD 61+ were taken as PMPs.

Results: There was significant difference between Hemoglobin, total leucocyte count, platelet count and Annexin V between cases and controls as p< 0.05. PMPs ranged from 2± 169 with a mean ± SD 53.7 ±57.49 in controls and from 36 ± 2256 with a mean ± SD 574.50 ±647.98 in diabetic cases while PMPs in the complicated diabetes group was from 848.42± 810.51 (78-2264). Thus, higher levels of PMPs were seen in Diabetes and Diabetic complications and the difference was statistically significant.

Conclusion: Thus, this study shows that there is an increase in the levels of PMPs in DM and its complications and thus can play a role in the thrombotic state of the disease as well as can give rise to various DM related complications.
Value Relevance of Accounting Information from PSAK 72
Authors: Mubarika Natatsa Rizqina , Handayani Rr. Sri
Published: June 2022

This study examines the value relevance of accounting information after PSAK 72 on the companies that are listed on Indonesia Stock Exchange. Ohlson’s model is used to evaluate the research hypothesis and to estimate the research model using Generalized Least Squares (GLS) regression analysis. The results indicate that applying PSAK 72 has value relevance to accounting information. Stock price significantly correlates with the company’s earnings, but the book value of equity has no value. PSAK 72 requires professional interpretation and judgment, which resulted in the recognition of differences for similar transactions. The complexity of PSAK 72 requires adjustments for the company to reduce profits, and it will react negatively to the users. PSAK 72 will better disclose its contract revenue with customers, but it requires lengthy preparation. To provide better information, IAI (Ikatan Akuntan Indonesia) needs to consider the transition period for the implementation.
SAMHSA announces new Recovery Innovation Challenge
Authors: Knopf Alison
Published: June 2022

Last month, the Substance Abuse and Mental Health Services Administration (SAMHSA) announced its first‐ever Behavioral Health Recovery Innovation Challenge. The goal is to identify innovations developed by peer‐run or community‐based organizations (and entities that may partner with them), such as local or state governments, health systems, hospitals, or health plans, that advance recovery.
Inflatable Origami: Multimodal Deformation via Multistability
Authors: Melancon David , Forte Antonio Elia , Kamp Leon M. , Gorissen Benjamin , Bertoldi Katia
Published: June 2022

Inflatable structures have become essential components in the design of soft robots and deployable systems as they enable dramatic shape change from a single pressure inlet. This simplicity, however, often brings a strict limitation: unimodal deformation upon inflation. Here, multistability is embraced to design modular, inflatable structures that can switch between distinct deformation modes as a response to a single input signal. This system comprises bistable origami modules in which pressure is used to trigger a snap‐through transition between a state of deformation characterized by simple deployment to a state characterized by bending deformation. By assembling different modules and tuning their geometry to cause snapping at different pressure thresholds, structures capable of complex deformations that can be pre‐programmed and activated using only one pressure source are created. This approach puts forward multistability as a paradigm to eliminate a one‐to‐one relation between input signal and deformation mode in inflatable systems.
Rational Design of Multifunctional CuS Nanoparticle‐PEG Composite Soft Hydrogel‐Coated 3D Hard Polycaprolactone Scaffolds for Efficient Bone Regeneration
Authors: Xue Xu , Zhang Hao , Liu Han , Wang Sicheng , Li Jiadong , Zhou Qirong , Chen Xiao , Ren Xiaoxiang , Jing Yingying , Deng Yonghui , Geng Zhen , Wang Xiuhui , Su Jiacan
Published: June 2022

3D‐printed polycaprolactone (PCL) scaffolds have been extensively studied for application in bone tissue engineering. However, PCL‐based scaffolds with enhanced bioactivity and intelligent delivery capability for bone repair remains challenging. Herein, CuS nanoparticle‐PEG soft hydrogel‐coated 3D hard polycaprolactone scaffolds (denoted as CuS‐PEG‐PCL scaffold) are rationally designed for efficient bone regeneration. CuS nanoparticles cross‐linked PEG hydrogel (CuS‐PEG‐hydrogel) endows the PCL‐based scaffold with excellent photothermal properties and stable soft elasticity, while the PCL scaffold provides excellent mechanical performance. Upon exposure to 1064 nm near‐infrared (NIR) light irradiation, dexamethasone sodium phosphate (Dexp), stored in the CuS‐PEG‐PCL scaffold, can be controllably released, which efficiently promotes osteogenic differentiation of bone mesenchymal stem cells (BMSCs). In addition, the combination of mild heating at 42 ± 0.5 °C further promoted osteogenic differentiation of BMSCs. Subsequently, this Dexp‐loaded CuS‐PEG‐PCL scaffold (D‐CuS‐PEG‐PCL scaffold) with NIR light treatment at the tibial defect of rats presented the highest bone regeneration capacity. These findings demonstrate that the Dexp‐loaded CuS‐PEG‐hydrogel can effectively modify the 3D printed PCL scaffold. Therefore, this multifunctional scaffold with a soft‐hard hybrid structure has the potential to become an advanced drug delivery vehicle in the treatment of large bone defects.
Surface‐Decorated High‐Entropy Alloy Catalysts with Significantly Boosted Activity and Stability
Authors: Zeng Kaizhu , Zhang Jianwei , Gao Wenqiang , Wu Lianping , Liu Hanwen , Gao Jinlong , Li Zezhou , Zhou Jihan , Li Teng , Liang Zhiqiang , Xu Bingjun , Yao Yonggang
Published: June 2022

High‐entropy alloy (HEA) nanoparticles are emerging catalytic materials and are particularly attractive for multi‐step reactions due to their diverse active sites and multielement tunability. However, their design and optimization often involve lengthy efforts due to the vast multielement space and unidentified active sites. Herein, surface decoration of HEA nanoparticles to drastically improve the overall activity, stability, and reduce cost is reported. A two‐step process is employed to first synthesize non‐noble HEA (FeCoNiSn) nanoparticles and then are surface alloyed with Pd (main active site), denoted as NHEA@NHEA‐Pd. As a demonstration in the ethanol oxidation reaction, a high mass activity of 7.34 A mg−1Pd and superior stability (>91.8% retention after 2000 cycles) in NHEA@NHEA‐Pd are achieved, substantially outperforming traditional HEA, binary M@M‐Pd (M = Sn, Fe, Co, Ni), and commercial Pd/C. In situ spectroscopy reveals that NHEA@NHEA‐Pd can catalytically produce and oxidize CO at <0.5 V, which is >200 mV lower than Sn@Sn‐Pd, suggesting enhanced activity in NHEA@NHEA‐Pd owing to Pd's unique high‐entropy coordination environment. This work provides a novel design of HEA catalysts by combining surface decoration (exposing more active sites) and high‐entropy coordination (enhancing intrinsic activity and structural stability) to boost catalysts’ activity and durability.
Two‐Color Strip‐Patterned White OLEDs: Tunable Color‐Temperature via Pattern Dimension Control
Authors: Han Dongheon , Lee Myeongjae , Jang Wooik , Lee Seunghan , Yang Jeehye , Jo Hyunwoo , Lee Hojin , Kwak Kyungwon , Kim BongSoo , Kang Moon Sung
Published: June 2022

White light is attained by combining different‐colored emissions. White organic light‐emitting diodes, therefore, should be fabricated to obtain mixed emissions from different organic luminophores while suppressing energy transfer between each other. Here, the authors present a simple means to realize this goal by forming two‐color strip‐patterns of light‐emitting polymer (orange) and an iridium complex (sky‐blue) luminophores entirely through solution processes. The formation of the two‐color patterns is facilitated by i) the use of a highly efficient crosslinker permitting the construction of structurally robust orange primary strip‐patterns and ii) the contrast in the surface energy allowing selective wetting of the secondary sky‐blue patterns between the orange primary patterns. The emissive layer comprising the two‐color strip ‐patterns allows for the mixing ratio of the two colors to be adjusted by simply varying the areal ratio of the two patterns, which in turn, controls the white emission color‐temperature from 2119 to 7994 K.
A Facile, Fabric Compatible, and Flexible Borophene Nanocomposites for Self‐Powered Smart Assistive and Wound Healing Applications
Authors: Chen Shuo‐Wen , Huang Shih‐Min , Wu Han‐Song , Pan Wei‐Pang , Wei Shih‐Min , Peng Chih‐Wei , Ni I‐Chih , Murti Bayu Tri , Tsai Meng‐Lin , Wu Chih‐I , Yang Po‐Kang
Published: June 2022

Smart fabrics that can harvest ambient energy and provide diverse sensing functionality via triboelectric effects have evoked great interest for next‐generation healthcare electronics. Herein, a novel borophene/ecoflex nanocomposite is developed as a promising triboelectric material with tailorability, durability, mechanical stability, and flexibility. The addition of borophene nanosheets enables the borophene/ecoflex nanocomposite to exhibit tunable surface triboelectricity investigated by Kelvin probe force microscopy. The borophene/ecoflex nanocomposite is further fabricated into a fabric‐based triboelectric nanogenerator (B‐TENG) for mechanical energy harvesting, medical assistive system, and wound healing applications. The durability of B‐TENG provides consistent output performance even after severe deformation treatments, such as folding, stretching, twisting, and washing procedures. Moreover, the B‐TENG is integrated into a smart keyboard configuration combined with a robotic system to perform an upper‐limb medical assistive interface. Furthermore, the B‐TENG is also applied as an active gait phase sensing system for instantaneous lower‐limb gait phase visualization. Most importantly, the B‐TENG can be regarded as a self‐powered in vitro electrical stimulation device to conduct continuous wound monitoring and therapy. The as‐designed B‐TENG not only demonstrates great potential for multifunctional self‐powered healthcare sensors, but also for the promising advancements toward wearable medical assistive and therapeutic systems.
Piezo‐Electrocatalysis for CO2 Reduction Driven by Vibration
Authors: Ma Jiangping , Jing Shaojie , Wang Yang , Liu Xue , Gan Li‐Yong , Wang Cong , Dai Ji‐Yan , Han Xiaodong , Zhou Xiaoyuan
Published: June 2022

With rising CO2 emissions caused by the massive consumption of fossil fuels, it is highly desirable to develop strategies that adopt renewable energy to convert CO2 into value‐added chemical feedstocks. Over the past decades, photocatalytic reduction of CO2 using light energy has attracted considerable attention. However, the advanced photocatalysis techniques cannot exert their action where light is unavailable. Here, a method for CO2 reduction on basis of vibration‐driven piezoelectricity to yield a piezo‐electrocatalysis effect which requires mechanical vibration rather than light, is proposed. Under mild vibration and sacrificial agent‐free conditions, the piezoelectric BaTiO3 catalyst provides a suitable piezo‐potential to overcome the redox potential of CO2 and convert it into CO with a maximum yield of 63.3 µmol g−1, achieving a reactivity comparable to those of photocatalysts. The piezo‐electrocatalytic CO2 reduction reaction adds a new avenue in addition to the existing photocatalytic techniques by expanding the scope of energy utilization to promote carbon neutrality.
Alternative Benzoxazole Assembly Discovered in Anaerobic Bacteria Provides Access to Privileged Heterocyclic Scaffold
Authors: Horch Therese , Molloy Evelyn M. , Bredy Florian , Haensch Veit G. , Scherlach Kirstin , Dunbar Kyle L. , Franke Jonathan , Hertweck Christian
Published: June 2022

Benzoxazole scaffolds feature prominently in diverse synthetic and natural product‐derived pharmaceuticals. Our understanding of their bacterial biosynthesis is, however, limited to ortho‐substituted heterocycles from actinomycetes. We report an overlooked biosynthetic pathway in anaerobic bacteria (typified in Clostridium cavendishii) that expands the benzoxazole chemical space to meta‐substituted heterocycles and heralds a distribution beyond Actinobacteria. The first benzoxazoles from the anaerobic realm (closoxazole A and B) were elucidated by NMR and chemical synthesis. By genome editing in the native producer, heterologous expression in Escherichia coli, and systematic pathway dissection we show that closoxazole biosynthesis invokes an unprecedented precursor usage (3‐amino‐4‐hydroxybenzoate) and manner of assembly. Synthetic utility was demonstrated by the precursor‐directed biosynthesis of a tafamidis analogue. A bioinformatic survey reveals the pervasiveness of related gene clusters in diverse bacterial phyla.
A Lattice‐Matching Strategy for Highly Reversible Copper‐Metal Anodes in Aqueous Batteries
Authors: Cai Haixia , Bi Songshan , Wang Rui , Liu Lili , Niu Zhiqiang
Published: June 2022

Copper metal is an attractive anode material for aqueous rechargeable batteries due to its high theoretical specific capacity (844 mAh g−1), good environmental compatibility and high earth abundance. However, the Cu anodes often suffer from poor deposition/stripping reversibility and nonuniform deposition during the charge/discharge process, degrading the lifetime of aqueous Cu‐metal batteries. Herein, a lattice‐matching strategy was developed to design high‐performance Cu‐metal anodes. In such a strategy, Ni substrates that exhibit high lattice matching with Cu were selected to support the Cu anodes. The high lattice matching endows Cu anodes with high deposition/stripping reversibility, low nucleation overpotential as well as a uniform and dense electrodeposition on Ni substrates. Based on the Ni substrate‐supported Cu anodes, the full cells paired with lead dioxide cathodes show a stable cycling behavior. This work provides a route for the design of high‐performance Cu electrodes in aqueous rechargeable batteries.
Expanded Azaporphyrins Consisting of Multiple BODIPY Units: Global Aromaticity and High Affinities Towards Alkali Metal Ions
Authors: Rao Yutao , Xu Ling , Zhou Mingbo , Yin Bangshao , Osuka Atsuhiro , Song Jianxin
Published: June 2022

The one‐pot self‐coupling reaction of 3‐amino‐5‐bromo‐BODIPY 9 under Buchwald–Hartwig amination conditions gave nitrogen‐bridged cyclic BODIPY tetramer 10, pentamer 11, and hexamer 12. Oxidation of 10, 11, and 12 in the presence of alkali metal ions provided 13, 15, and 16, respectively, as the first examples of expanded azaporphyrins possessing more than six pyrrole rings. Curiously, the oxidation even in the absence of alkali metal ions gave the same complexes as a result of spontaneous complexation. 10–12 showed large association constants (104–106 M−1) with K+ and Na+, but the spontaneous complexations were not observed, indicating the extremely high affinities of 13–16 toward alkali metal ions, which can be ascribed to the multiple and effective ion–dipole interaction of the alkali metal ion with the negatively polarized F atoms of the BF2 walls surrounding the cavity. Importantly, 13, 14, and 15 show diatropic ring currents as a result of global aromaticity.