bluuebunny/crossref_metadata_2025 huggingface dataset:
Nanoparticles as Delivery Systems for Antigenic Saccharides: From Conjugation Chemistry to Vaccine Design
Authors: Archambault Marie-Jeanne , Tshibwabwa Laetitia Mwadi , Côté-Cyr Mélanie , Moffet Serge , Shiao Tze Chieh , Bourgault Steve
Published: November 2024

Glycoconjugate vaccines have been effective in preventing numerous bacterial infectious diseases and have shown recent potential to treat cancers through active immunotherapy. Soluble polysaccharides elicit short-lasting immune responses and are usually covalently linked to immunogenic carrier proteins to enhance the antigen-specific immune response by stimulating T-cell-dependent mechanisms. Nonetheless, the conjugation of purified polysaccharides to carrier proteins complexifies vaccine production, and immunization with protein glycoconjugates can lead to the undesirable immunogenic interference of the carrier. Recently, the use of nanoparticles and nanoassemblies for the delivery of antigenic saccharides has gathered attention from the scientific community. Nanoparticles can be easily functionalized with a diversity of functionalities, including T-cell epitope, immunomodulator and synthetic saccharides, allowing for the modulation and polarization of the glycoantigen-specific immune response. Notably, the conjugation of glycan to nanoparticles protects the antigens from degradation and enhances their uptake by immune cells. Different types of nanoparticles, such as liposomes assembled from lipids, inorganic nanoparticles, virus-like particles and dendrimers, have been explored for glycovaccine design. The versatility of nanoparticles and their ability to induce robust immune responses make them attractive delivery platforms for antigenic saccharides. The present review aims at summarizing recent advancements in the use of nano-scaled systems for the delivery of synthetic glycoantigens. After briefly presenting the immunological mechanisms required to promote a robust immune response against antigenic saccharides, this review will offer an overview of the current trends in the nanoparticle-based delivery of glycoantigens.
Human Papillomavirus-Related Cancer Vaccine Strategies
Authors: Cai Xia , Xu Ling
Published: November 2024

Background: Human papillomavirus (HPV) persistent infection is a major pathogenic factor for HPV-related cancers, such as cervical cancer (CC), vaginal cancer, vulvar cancer, anal cancer, penile cancer, and head and neck cancer (HNC). Since the introduction of the world’s first prophylactic HPV vaccine, there has been a decline in the incidence of HPV infections and associated cancers. This article reviews the latest literature on the research progress, efficacy, and safety of HPV vaccines for these cancers, providing a reference for HPV vaccination strategy. Methods: By utilizing databases such as PubMed, Google Scholar, CNKI, and Wanfang, we conducted a literature search on research papers related to HPV vaccines from 2014 to 2024, employing keywords such as “HPV”, “HPV vaccine”, “CC”, ”vaginal cancer”, “vulvar cancer”, “anal cancer”, “penile cancer” and “HNC”. Additionally, we reviewed the latest information available on official websites, including the World Health Organization (WHO). Based on the quality and relevance of the papers, we selected over 100 of the most representative articles for further summarization and analysis. Results: Vaccination against HPV can effectively block the transmission of the virus and prevent HPV-related cancers. Current studies have confirmed the efficacy and safety of prophylactic HPV vaccination. However, numerous challenges remain. The global vaccination rate for preventive vaccines remains low, particularly in low- and middle-income countries. Nonetheless, in the future, we can enhance the accessibility, affordability, and coverage of HPV vaccines by expanding the indications of already licensed vaccines, continuously developing new vaccines. Conclusions: The HPV vaccine is an extremely effective measure for the prevention and treatment of HPV-related cancers. Although there are many challenges in expanding the coverage of the HPV vaccine. It is believed that in the not-too-distant future, both prophylactic and therapeutic HPV vaccines will achieve commendable results.
Human Papillomavirus (HPV) Vaccination: Progress, Challenges, and Future Directions in Global Immunization Strategies
Authors: Branda Francesco , Pavia Grazia , Ciccozzi Alessandra , Quirino Angela , Marascio Nadia , Gigliotti Simona , Matera Giovanni , Romano Chiara , Locci Chiara , Azzena Ilenia , Pascale Noemi , Sanna Daria , Casu Marco , Ceccarelli Giancarlo , Ciccozzi Massimo , Scarpa Fabio
Published: November 2024

Human papillomavirus (HPV) is a widespread viral pathogen, responsible for a significant burden of cervical and other cancers worldwide. Over the past decades, the development and widespread adoption of prophylactic HPV vaccines have dramatically reduced the incidence of HPV-related diseases. However, despite the efficacy of these vaccines, global immunization efforts still face several obstacles, including low vaccination coverage in low- and middle-income countries, vaccine hesitancy, and disparities in access to healthcare. This review aims to provide a comprehensive overview of the current state of HPV vaccines, including their mechanisms of action, safety profiles, and real-world efficacy. We will explore the impact of HPV vaccines on cancer prevention, examine the challenges related to vaccine distribution and uptake, and assess the role of public health policies in improving global vaccination rates. Additionally, the review will highlight the latest advancements in therapeutic HPV vaccines, ongoing research into next-generation vaccines, and the potential of HPV vaccination strategies in the context of personalized medicine. By examining these factors, we aim to provide insights into the future directions of HPV vaccination and its role in global public health.
Extensive Epidural Hemorrhage Associated with Thoracolumbar Disc Extrusion in French Bulldogs
Authors: Underberg Julius , Maiolini Arianna , Waschk Maja , Schweizer Daniela
Published: November 2024

(1) Background: Intervertebral disc extrusion may be accompanied by extensive epidural hemorrhage (EEH) and result in spinal cord compression. EEH is more commonly seen in French Bulldogs compared to other breeds. The majority of French Bulldogs have lumbar intervertebral disc extrusion, but it is unclear if there is an association between the site of thoracolumbar disc extrusion and EEH. This retrospective study’s aim was to investigate the association and prevalence between the site of thoracolumbar intervertebral disc extrusion and EEH in French Bulldogs. (2) Methods: Thoracolumbar MRI of French Bulldogs was examined for the site of intervertebral disc extrusion and the presence, distribution, and extent of EEH. (3) Results: In 148 French Bulldogs with thoracolumbar intervertebral disc extrusion, the most common location was L4/L5 (22%), followed by L3/L4 (20%) and T13/L1 (15%), and 70.3% had EEH. The highest incidence of EEH across all thoracolumbar sites was seen at L1/L2 (84.2%), followed by L5/L6 (81.3%) and L2/L3 (72.2%). The incidence of EEH was 70.5% across all lumbar sites and 66.9% for all thoracic sites. (4) Conclusion: In this population of French Bulldogs, the prevalence of lumbar disc extrusion was high, and 70.3% had EEH. There was no significant difference between the site of thoracolumbar intervertebral disc extrusion and EEH.
Effects of Dietary Cobalt Levels on Growth Performance, Antioxidant Capacity, and Immune Status of Juvenile Largemouth Bass (Micropterus salmoides)
Authors: Huang Dongyu , Jahazi Joshua Daniel , Ren Mingchun , Zhang Lu , Liang Hualiang
Published: November 2024

A 9-week experiment investigated the effects of dietary cobalt levels on the growth performance, antioxidant capacity, and immunity of largemouth bass. Six feed groups were designed and each group received different cobalt levels, including 0.129 mg/kg (control group), 0.192 mg/kg, 0.201 mg/kg, 0.233 mg/kg, 0.277 mg/kg, and 0.316 mg/kg. The results show that the control group (0.129 mg/kg diet) had the lowest final body weight (FBW), weight gain rate (WGR), and specific growth rate (SGR), and the highest feed conversion ratio (FCR), when compared to the cobalt supplementation groups. Dietary cobalt levels of 0.192 mg/kg increased the body protein content and decreased the body moisture content. Regarding antioxidant capacity, the highest catalase (CAT) activity was found in the 0.277 mg/kg dietary cobalt group, while the malondialdehyde (MDA) content was significantly diminished; the total antioxidant capacity (T-AOC) content and glutathione peroxidase (GSH-Px) activity exhibited the highest values in the 0.192 mg/kg and 0.233 mg/kg dietary cobalt groups, respectively. Regarding gene expression, compared with the control group, the mRNA expression of sod was upregulated in the 0.192 mg/kg, 0.233 mg/kg, and 0.277 mg/kg dietary cobalt groups, while the mRNA expression of gpx was diminished when dietary cobalt levels were below 0.233 mg/kg. In addition, the highest il-10 and tgf-β mRNA expression levels were observed in the 0.201 mg/kg and 0.233 mg/kg dietary cobalt groups, respectively. According to the quadratic regression analysis based on the SGR and FCR, the optimal requirement was 0.24 and 0.26 mg/kg of dietary cobalt, respectively.
Research on the Smooth Switching Control Strategy of Electric Vehicle Charging Stations Based on Photovoltaic–Storage–Charging Integration
Authors: Wang Tao , Ma Jinghao , Lin Cunhao , Li Xin , Chen Shenhui , Zhang Jihui
Published: November 2024

To facilitate seamless transitions between grid-connected and islanded modes in PV–storage–charging integration, an energy storage system converter is designated as the subject of investigation, and its operational principles are examined. Feed-forward decoupling, double closed-loop, constant-power (PQ), constant-voltage–constant-frequency (V/F), and constant-voltage charge and discharge control strategies are developed. The PQ and V/F control framework of the energy storage battery comprises an enhanced common current inner loop and a switching voltage outer loop. The current reference value output by the voltage outer loop and the voltage signal output by the current inner loop are compensated. The transient impact is reduced, and the smooth switching of the microgrid from the grid-connected mode to the island mode is realized, which significantly improves the power quality and ensures the uninterrupted charging of electric vehicles and the stable operation of the key load of the system. By constructing a simulation model of the photovoltaic energy storage microgrid on the MATLAB/Simulink platform, the practicability of the control strategy proposed in this paper is verified.
An Adaptive Cruise Control Strategy for Intelligent Vehicles Based on Hierarchical Control
Authors: Hu Di , Zhao Jingbo , Zheng Jianfeng , Liu Haimei
Published: November 2024

To minimize the occurrence of traffic accidents, such as vehicle rear-end collisions, while enhancing vehicle following, stability, economy, and ride comfort, a hierarchical adaptive cruise control strategy for vehicles is proposed. The upper-level controller computes the desired vehicle output acceleration based on model predictive control and switches between speed and spacing control in accordance with driving conditions. The brake/throttle opening switching model, brake control inverse model, and throttle opening inverse model in the lower-level controller of ACC are designed to obtain the desired throttle opening and braking pressure of the vehicle, thereby achieving control of the vehicle. A joint simulation platform was established using PreScan, CarSim and Matlab/Simulink. Finally, simulations for three typical working conditions were conducted in Simulink to verify the performance of the adaptive cruise control strategy. The results indicate that, in both the constant-speed cruise and vehicle-following cruise conditions, the vehicle can rapidly and stably follow the set initial speed and consistently maintain a safe distance from the preceding vehicle. Under the emergency braking condition, the vehicle can promptly respond with deceleration, ensuring driving safety. The proposed control strategy can accurately and safely track the target vehicle in diverse driving conditions and can concurrently fulfill the requirements of economy and comfort during vehicle travel.
Optimal Driving Torque Control Strategy for Front and Rear Independently Driven Electric Vehicles Based on Online Real-Time Model Predictive Control
Authors: Yin Hang , Ma Chao , Wang Haifeng , Sun Zhihao , Yang Kun
Published: November 2024

This paper presents a novel driving torque control strategy for the front and rear independently driven electric vehicle (FRIDEV) to reduce energy consumption and enhance vehicle stability. The strategy is built on a comprehensive vehicle model that integrates vertical load transfer, tire slip dynamics, and an electric system model that accounts for losses in induction motors (IMs), permanent magnet synchronous motors (PMSMs), inverters, and batteries. The torque control problem is framed with a nonlinear model predictive control (MPC) method, utilizing state-space equations as representations of vehicle dynamics. The optimization targets adjust in real-time based on road traction conditions, with the slip rate of front and rear wheels determining the torque control strategy. Active slip control is applied when slip rates exceed critical thresholds, while under normal conditions, torque distribution is optimized to minimize energy losses. To enable online real-time implementation, an improved sparrow search algorithm (SSA) is designed. Simulations in MATLAB/Simulink confirm that the proposed online strategy reduces energy consumption by 2.3% under the China light-duty vehicle test cycle-passenger cars (CLTC-P) compared to a rule-based strategy. Under low-adhesion conditions, the proposed online strategy effectively manages slip ratios, ensuring stability and performance. Improved SSA also enhances computational efficiency by approximately 44%–52%, making the online strategy viable for real-time applications.
Identidades: Acercamiento a la Identidad Juvenil
Authors: De la Llana Pérez Evelyn , Bringas León Sheila , Cruzata Walter Jorge
Published: November 2024

La cuestión de las identidades se torna recurrente en este nuevo siglo. Nos encontramos en un constante enfrentamiento entre la equidad, justicia social y las tendencias de globalizar un mundo dominado por el capital transnacional. Ante esta disyuntiva, las identidades irrumpen en el contexto social como un arma poderosa en defensa de las tradiciones históricas y culturales de las diversas comunidades. Este tema ha sido el epicentro de valoraciones de aquellos que han intentado argumentar las diferencias, especificidades y semejanzas culturales en el desarrollo de los pueblos, así como, la formación de sus cualidades y la manera de expresarlas. Sin embargo, como todo proceso intra e intersubjetivo, la formación de las características identitarias de un individuo, grupo o colectividad es continua, matizada por momentos de ruptura, que obligan a la redimensión de los significados y permiten su permanente evolución. El presente artículo analiza las diferentes perspectivas teóricas y posturas, referente al tema de la construcción de la identidad y en especial la identidad juvenil.
Factores que Influyen para la Transformación Digital de Nuevas Empresas Ecuatorianas
Authors: Cando Cedeño Jordan Lindon , Cando Cedeño Jhonson Orlando
Published: November 2024

Cuando se juntan factores como el confinamiento y el continuo progreso empresarial se crea el ambiente perfecto para la expansión de las actividades comerciales, pero en torno a un contexto digital; es por ello que el presente artículo tiene como objetivo analizar los factores que son necesarios para potencializar la transformación digital en las empresas de la Zona 8 de Ecuador a raíz de la pandemia del covid-19. Se efectuó una metodología de carácter inductivo-deductivo, el instrumento fueron las encuestas, y se aplicó a 61 estudiantes de administración de la universidad de Guayaquil con negocios para determinar los puntos críticos que las empresas deben afrontar para alcanzar una transformación digital, dando como resultado la desconfianza, la competencia, la portabilidad, entre otros.
Vínculo universidad–empresa en la formación de profesionales. Resulados y experiencias en la universidad de oriente, Cuba
Authors: Ruiz Ducasse David , Dulayna Pineda Ramos , Ocejo Salvador Aida María
Published: November 2024

El vínculo Universidad - Empresa parte de determinar los problemas profesionales acordes al perfil ocupacional, esta se materializa en el desarrollo de la práctica laboral de los estudiantes. El artículo es el resultado de una investigación cualitativa desarrollada en cinco años. Se ofrecen resultados alcanzados por las carreras con las entidades tanto en la producción y los servicios, en la formación del profesional y el desarrollo local, siendo posible por el análisis, la triangulación y la sistematización minuciosa de fuentes teóricas investigativas que permitieron sacar inferencias y profundizar en la organización y planificación de las actividades. Se hace patente la responsabilidad que tienen las entidades y los organismos en la formación de un profesional competente en alianza con las universidades.
Las cuestiones de género e indígenas en revistas latinoamericanas de Geografía entre 1990 y 2021
Authors: Cabre Pilar Guadalupe , Brasca Micaela
Published: November 2024

Este trabajo surge de la necesidad de conocer el estado del arte en torno a la producción científica dentro de la Geografía con respecto a las mujeres indígenas. En este sentido, se propone relevar publicaciones en revistas latinoamericanas de Geografía en línea, entre 1990 y 2021, donde se aborden de manera conjunta las categorías de género y cuestión étnica, así como identificar los principales conceptos utilizados. A través de metodologías cuantitativas, se seleccionan y sistematizan publicaciones en revistas de Geografía vinculadas a las categorías de género y etnia. Además, mediante el análisis de contenido, se identifican los principales temas, metodologías y discusiones teóricas presentes en dichas publicaciones. El trabajo revisa un total de 71 revistas, de las cuales se seleccionaron 18 publicaciones por su pertinencia temática. Estos artículos se agruparon en cuatro líneas principales: territorialidades y prácticas cotidianas, participación política, trabajo y condiciones de vida, y cuestiones de género e indígenas. Entre las principales conclusiones, se destaca que la temática representa un campo de conocimiento emergente, siendo estas discusiones parte de un universo reducido de revistas y publicaciones.
Pendugaan Area Kecil Tingkat Pengangguran Terbuka Level Kecamatan Di Provinsi Kepulauan Riau Tahun 2022
Authors: Puspita Desak Nyoman Febrina Ambara , Ubaidillah Azka
Published: November 2024

Kepulauan Riau merupakan provinsi dengan Tingkat Pengangguran Terbuka (TPT) tertinggi kedua pada tahun 2022. TPT Kepulauan Riau pernah melonjak dua kali lipat pada periode satu dekade terakhir, yaitu 5,08 persen pada Agustus 2012 menjadi 10,34 persen pada Agustus 2020. Kepulauan Riau memiliki pengangguran yang putus asa mencapai 31,8 persen. Kebijakan pengentasan pengangguran lebih efisien jika difokuskan pada pemerintahan kecil seperti kecamatan. Namun, data TPT hanya tersedia hingga level kabupaten/kota. Sakernas Agustus 2022 tidak memiliki ukuran sampel yang cukup untuk mengestimasi TPT level kecamatan. Maka, penelitian ini bertujuan mengestimasi TPT level kecamatan di Kepulauan Riau tahun 2022 menggunakan Small Area Estimation (SAE) dengan informasi tambahan dari potensi Desa 2021. Hasil penelitian menunjukkan bahwa SAE Hierarchical Bayes Beta menghasilkan penduga TPT kecamatan dengan relative standard error yang lebih kecil dibandingkan pendugaan langsung. Kecamatan bernilai TPT tinggi di Kepulauan Riau tersebar di wilayah perkotaan sehingga memerlukan kebijakan khusus dalam menekan angka pengangguran.
Peramalan Produksi Minyak dan Gas Bumi di Indonesia
Authors: Gampar Yohanes Apriyano , Agustina Neli
Published: November 2024

Sektor minyak dan gas bumi (migas) masih menjadi tumpuan penggunaan energi primer di Indonesia. Namun, masalah yang dihadapi dalam industri migas yaitu penurunan produksi migas dari tahun ke tahun. Kondisi tersebut memerlukan kebijakan dan keputusan terkait pengelolaan migas yang tepat agar mencapai ketahanan dan kemandirian energi migas melalui data hasil peramalan. Melalui hasil peramalan dapat memperkirakan realisasi terhadap target RPJMN untuk produksi migas 2023 – 2024. Penelitian ini bertujuan untuk menganalisis gambaran umum produksi migas Indonesia periode triwulan I 2007 hingga triwulan II 2023, menentukan model peramalan terbaik dengan membandingkan metode Holt’s Double Exponential Smoothing dan ARIMA, dan meramalkan produksi migas periode triwulan III 2023 hingga triwulan IV 2024 dengan metode terbaik. Hasil penelitian menunjukkan produksi migas mengalami penurunan dengan rata-rata laju pertumbuhan sebesar -0,69 persen dan -0,48 persen. Metode terbaik untuk meramalkan produksi minyak bumi adalah Holt’s Double Exponential Smoothing dan untuk meramalkan produksi gas bumi adalah ARIMA. Hasil peramalan menunjukkan produksi minyak bumi mengalami penurunan dengan rata-rata produksi sebesar 52.763,19 ribu barel dan produksi gas bumi mengalami kenaikkan dengan rata-rata produksi sebesar 493.306,05 MMscf selama enam triwulan ke depan. Kondisi tersebut menunjukkan bahwa target produksi migas dari RPJMN Ditjen Migas 2023 – 2024 masih belum tercapai.
Potensi Pemanfaatan Machine Learning dan Transfer Learning untuk Klasifikasi Baku Pekerjaan
Authors: Dwicahayaniawan Agnes Septi , Saadi Terry Devara Tri
Published: November 2024

Pemantauan kondisi data ketenagakerjaan di Indonesia melibatkan klasifikasi baku untuk memberikan keseragaman konsep. Proses pengkodean sangat bergantung pada pengetahuan petugas, yang seringkali dapat menimbulkan permasalahan seperti kemungkinan adanya perbedaan pemahaman dan interpretasi antar individu yang menyebabkan inkonsistensi hasil pengkodean klasifikasi baku. Penelitian ini bertujuan untuk mengeksplorasi peluang pemanfaatan Machine Learning dalam pengkodean Klasifikasi Lapangan Usaha Indonesia (KBLI) dan Klasifikasi Baku Jabatan Indonesia (KBJI). Model dikembangkan dan dievaluasi untuk melakukan klasifikasi kode KBLI dan KBJI berdasarkan pertanyaan terbuka mengenai apa yang dikerjakan, output yang dihasilkan dan bidang pekerjaan oleh responden yang dikumpulkan melalui Survei Angkatan Kerja Nasional (Sakernas). Hasil penelitian menunjukkan bahwa walaupun hasil performa metode IndoBERT sedikit lebih unggul dengan angka accuracy sebesar 0,76 pada pemodelan KBLI dan 0,65 untuk KBJI. Keunggulan tersebut tidak terlalu signifikan dengan beban komputasi yang lebih besar dan proses training yang menghabiskan waktu lebih lama dibanding machine learning.
Pembangunan Chatbot Sistem Informasi KBLI dan KBJI Berbasis LLM
Authors: Anassai Bayu Rayhan , Josaphat Bony Parulian
Published: November 2024

Badan Pusat Statistik (BPS) mengumpulkan data melalui sensus dan survei untuk menyediakan data kepada pemerintah dan masyarakat. Data ini didapat dari kuesioner yang berisi pertanyaan terbuka dan tertutup. Salah satu pertanyaan terbuka yang diajukan adalah mengenai pekerjaan responden yang nantinya akan disimpulkan dengan pemberian kode KBLI dan KBJI. KBLI dan KBJI adalah klasifikasi yang digunakan BPS untuk mengklasifikasikan kegiatan ekonomi. BPS menggunakan aplikasi Sibaku Mobile untuk memudahkan petugas dalam mengisi kode KBLI dan KBJI, namun aplikasi ini memiliki kekurangan bagi pengguna baru. Penelitian ini bertujuan untuk mengembangkan chatbot yang dapat memberikan kode KBLI/KBJI yang tepat menggunakan Large Language Models (LLM). Pembangunan chatbot dilakukan dengan metode prototyping. Evaluasi klasifikasi tujuan menunjukkan nilai accuracy, precision, recall, dan F1-score yang mendekati angka 97%. Evaluasi RAG robustness memperoleh nilai hallucination rate sebesar 0% dan error rate sebesar 7%. Usability testing menunjukkan tingkat penerimaan chatbot berada di angka 87.45%.
Pengelompokan Kabupaten/Kota Di Jawa Tengah Menurut Indeks Kerawanan Sosial Terhadap Demam Berdarah Dengue
Authors: Muzakky A. Naufal , Budiarti Winih
Published: November 2024

Tingginya angka kematian akibat DBD di Jawa Tengah membuat pemerintah perlu melakukan upaya dalam menurunkan beban penyakit DBD yaitu dengan mengurangi kerawanan dalam masyarakat atau kerawanan sosial terhadap DBD. Kerawanan sosial merupakan konsep multidimensi yang bisa diukur menggunakan indeks komposit. Indeks ini berguna untuk menentukan daerah dan dimensi prioritas kebijakan. Oleh karena itu, tujuan penelitian ini adalah menyusun Indeks Kerawanan Sosial terhadap DBD (IKS DBD) menggunakan analisis faktor, mengelompokkan kabupaten/kota berdasarkan IKS DBD, serta mengidentifikasi dimensi prioritas kebijakan. Hasil penelitian menunjukkan bahwa terdapat empat faktor penyusun IKS DBD yaitu sosioekonomi dan perkotaan, layanan kesehatan, penduduk rentan, serta perumahan. Pengelompokan kabupaten/kota menghasilkan lima kategori kerawanan yaitu kerawanan sangat tinggi, tinggi, sedang, rendah, dan sangat rendah. Dari radar plot yang dihasilkan, setiap kelompok memiliki dimensi prioritas kebijakan yang berbeda sehingga dapat membantu pemerintah dalam menentukan kebijakan yang berdampak signifikan.
Kajian Peningkatan Implementasi Sistem Akuntabilitas Kinerja Instansi Pemerintah Melalui Pembangunan Aplikasi Evaluasi Akuntabilitas Kinerja Instansi Pemerintah
Authors: Abdi Pradana Achmad Arfiandys , Maghfiroh Lutfi Rahmatuti
Published: November 2024

Inspektorat Utama Badan Pusat Statistik (BPS) merupakan unit kerja yang bertanggung jawab untuk melaksanakan evaluasi Akuntabilitas Kinerja Instansi Pemerintah (AKIP). Saat ini sistem yang digunakan dalam evaluasi masih memanfaatkan beberapa aplikasi pihak ketiga yang memiliki keterbatasan. Selain itu, dalam Laporan Hasil Evaluasi (LHE) BPS Republik Indonesia terdapat rekomendasi agar BPS memiliki aplikasi mandiri. Oleh karena itu, Inspektorat Utama perlu melakukan kajian terhadap peningkatan implementasi sistem akuntabilitas kinerja instansi pemerintah melalui pembangunan sebuah aplikasi yang dapat memenuhi kebutuhan tersebut. Pembangunan aplikasi diawali dengan pengumpulan data untuk analisis kebutuhan yang dilanjut dengan perancangan aplikasi, implementasi rancangan serta evaluasi dan pengujian. Aplikasi dibangun menggunakan metode System Development Life Cycle model iterative waterfall. Aplikasi yang telah dibangun, dievaluasi dengan Computer System Usability Questionnaire dan diuji menggunakan black box testing. Hasil pengujian aplikasi menunjukkan bahwa semua fungsi berjalan dengan semestinya, sedangkan hasil evaluasi menunjukkan pengguna sangat puas dengan kinerja dan tampilan aplikasi.
Pola Pernikahan Asortatif dan Ketimpangan Pengeluaran Penduduk di Jawa Barat
Authors: Kristy Nurine
Published: November 2024

Provinsi Jawa Barat merupakan provinsi dengan jumlah penduduk terbesar di Indonesia. Pertumbuhan ekonomi Jawa Barat tahun 2023 sebesar 5,05 persen, namun kesenjangan ekonomi terus meningkat setiap tahunnya. Pola pernikahan asortatif khususnya pendidikan diindikasikan turut serta memperlebar kesenjangan di masyarakat. Penelitian ini bertujuan untuk menganalisis pola pernikahan asortatif, baik ditinjau dari sisi usia maupun dari sisi pendidikan di Jawa Barat tahun 2022. Penelitian ini juga menganalisis hubungan antara pola pernikahan asortatif dan ketimpangan pengeluaran per kapita. Analisis berupa grafik, tabel, korelasi Kendall’s Tau, serta kurva Lorenz digunakan dalam penelitian ini. Data yang digunakan yaitu data Susenas Maret tahun 2022. Hasil analisis menunjukkan terjadi pernikahan asortatif di Jawa Barat dari sisi pendidikan. Pola pernikahan yang terjadi adalah pernikahan asortatif positif di seluruh kategori wilayah. Hubungan antara pola pernikahan asortatif dengan ketimpangan pengeluaran perkapita adalah terdapat indikasi pernikahan asortatif memiliki asosiasi dengan ketimpangan pengeluaran perkapita yang menjadi lebih buruk (lebih timpang).
Guidelines on Telerehabilitation for Breast Cancer Patients: Methodical Recommendations
Authors: Vladymyrov Oleksandr , Semykopna Tetiana , Vakulenko Dmytro , Syvak Oksana , Budnyk Mykola
Published: November 2024

This provides a comprehensive analysis of the current developments in telerehabilitation, focusing on the regulatory and legal frameworks for delivering telerehabilitation services, the clinical manifestations of postmastectomy pain syndrome, and the role and significance of the International Classification of Functioning, Disability, and Health (ICF) in the telerehabilitation of breast cancer (BC) patients. The document also explores telerehabilitation interventions for BC.

A detailed description of the software and hardware tools is provided, including the structural and functional overview of the Telerehabilitation Platform (TRP), software modules such as "Telerehabilitation," "Medical Reports," the Administrative Subsystem, the Information-Analytical Subsystem, which encompass the PM&R physician’s digital workspace, the PM&R Expert Subsystem, and the Patient’s digital workspace. It also covers existing and prospective scales for evaluating the effectiveness of telerehabilitation, as well as the specifics of working with identified patients in accordance with the eHealth (Electronic Healthcare System of Ukraine) requirements.

The guidelines conclude with organizational and methodological aspects for implementing telerehabilitation programs, including initial and stage-specific
rehabilitation assessments, basic ICF sets, and various patient-specific telerehabilitation programs. These includea patient-centered program for the preoperative stage of telerehabilitation and individualized programs for the post-acute and long-term phases. The eight appendices include questionnaires, physical therapy programs, protocols, diaries, and requirements for the equipment and staff of the telerehabilitation/telemedicine office, among other resources.
Influence of Tooth Loss and Malocclusions on Condylar Position - Analysis by Cone Beam Computed Tomography
Authors: Barbosa de Sousa Lara Lecy Nogueira , De Barros Silva Paulo Goberlânio , Linard Avelar Rafael , Tavares Pereira Filho Claudio Roberto , de Souza Maysa Luna , Araújo Sampaio Fernanda , de Melo Silva Jonathan Francisco , Cabral Thaís Cavalcante , Pinto Bandeira Lucas Muniz , Cetira Filho Edson Luiz , Barbosa Alencar Phillipe Nogueira
Published: November 2024

This study aimed to assess the position of the condyle in the condylar fossausing cone beam computed tomography in patients with tooth loss and malocclusion. A sample of 47 patients of both genders from the Unichristus Dentistry service was selected and divided into six groups. The division was as follows: 1. Angle Class I patients; 2. Angle Class II patients; 3. Angle Class III patients; 4. edentulous patients in both arches; 5. edentulous upper and partially edentulous lower patients; 6. patients with multiple losses. All the patients underwent closed-mouth cone-beam computed tomography, with exposure values of 85kVp, 6.3ma, and 20s of exposure. The images were analyzed in sagittal and axial sections on both sides. Data was expressed as mean and standard deviation, and the Kolmogorov-Smirnov normality test was used to compare theright and left sides or ANOVA/ Bonferroni for independent or repeated measures.
ASEAN Legal Mechanism in Geopolitical Conflict of the South China Sea
Authors: Abd Aziz Saidatul Nadia , Mat Basir Salawati
Published: November 2024

South China Sea competition is real and hostile. Following the South China Sea Arbitration, the dynamics of territorial sovereignty in the South China Sea have shifted considerably. The position of ASEAN as the most enduring regional organization in the "global south" faces challenges, particularly in balancing rising great power competition in the Indo-Pacific region. ASEAN as a regional institution may be able to deal with some uncertainties, but it is impossible to overcome the recurrent "power dilemma," particularly when powerful states are intent on disrupting the existing quo. However, ASEAN must continue to act as an impartial arbiter in a strategic environment characterized by competing interests. ASEAN cohesion is very important and if the territorial issue is not properly managed, it might jeopardize regional stability and affect all member states. Without cohesiveness and centrality, existing ASEAN mechanisms and multilateralism can never be successful, and great powers will continue to intervene in the region's affairs.
Design Thinking for Kami Peduli Website to Mobilize Community Disaster Response
Authors: Nanda Rifqi , Anggun Pratama Septiano , Pusadan Mohammad Yazdi , Anshori Yusuf
Published: November 2024

Central Sulawesi, particularly Palu City, is a disaster-prone area with communities lacking sufficient knowledge and preparation for natural disaster risks. This study aims to develop a sustainable digital platform that enhances community preparedness through a user-friendly and engaging website design. By applying the Design Thinking method, the platform integrates sustainable digital innovation to provide essential information on disaster-prone areas, volunteer opportunities, and donation channels. The platform’s design prioritizes efficient use of digital resources to minimize environmental impact, supporting long-term resilience and community mobilization. Utilizing both qualitative and quantitative approaches, data was gathered through questionnaires and interviews with PMI staff, volunteers, and the public. The Design Thinking stages: Empathize, Define, Ideate, Prototype, and Test, were employed to create a responsive and effective user experience. SEQ testing results revealed an average usability score of 4.25, highlighting the platform's ease of use. This project contributes to sustainable innovation in disaster preparedness by leveraging digital resources to empower communities in Central Sulawesi.
Проблемы и специфика подготовки кадров для сферы пожарной безопасности России
Authors: М.Н. Краснова , Л.В. Юшкова
Published: November 2024

Статья сосредотачивает внимание авторов на актуальных вопросах специфики подготовки кадров для сферы пожарной безопасности, в том числе в контексте взаимодействий разных органов системы подготовки, направлениях и качестве профессиональных компетенций специалистов разного уровня системы пожарной безопасности. Ключевым моментом статьи стал сравнительный анализ системы подготовки кадров гражданской службы государственного муниципального управления и кадров сферы пожарной безопасности в Российской Федерации. В статье обозначены основные проблемы качества подготовки сотрудников сферы пожарной безопасности: отсутствие нормативно-правовых регламентов взаимодействия высших профессиональных учебных заведений и комплектующих органов МЧС, недостаточное участие комплектующих органов МЧС России в формировании программ подготовки и оценке ее результатов на всех этапах реализации, отсутствие четкой обратной связи между уровнями подготовки, предполагающей понимание остаточных знаний и компетенций специалистов, отсутствие единой системы взаимодействия высших профессиональных учебных заведений и комплектующих органов МЧС.

The article focuses the authors' attention on topical issues of the specifics of personnel training for the field of fire safety, including in the context of interactions between different bodies of the training system, directions and quality of professional competencies of specialists of different levels of the fire safety system. The key point of the article was a comparative analysis of the training system of the civil service of the state municipal administration and personnel in the field of fire safety in the Russian Federation. The article identifies the main problems of the quality of training of employees in the field of fire safety: the lack of regulatory and legal regulations for the interaction of higher professional educational institutions and components of the Ministry of Emergency Situations, insufficient participation of components of the Ministry of Emergency Situations of Russia in the formation of training programs and evaluation of its results at all stages of implementation, lack of clear feedback between levels of training, assuming an understanding of residual knowledge and competencies specialists, the lack of a unified system of interaction between higher professional educational institutions and components of the Ministry of Emergency Situations.
Внедрение экологически значимых мероприятий на предприятии (на примере ООО завод горного оборудования)
Authors: А.А. Шивков , Е.В. Щербенко
Published: November 2024

Исследуется значение разработки экологической политики предприятия для реализации национальной экологической повестки устойчивого развития. Показано, что в текущий период мероприятия программ реализации экологической политики предприятий направлены на снижение степени загрязнения окружающей среды, обеспечение сокращения эксплуатационных затрат и выпуск промышленной продукции на принципах бережливого производства, активное внедрение современных экологических технологий, оборудования и материалов. Предложены рекомендации совершенствования технологической линии очистки сточных вод предприятия.

The article shows the role of the implementation of the environmental policy (EP) of the enterprise, organization and industry in the implementation of the national EP, which is the most important component of the sustainable development of the country in both the environmental and social spheres. It is established that the activities of environmental programs are primarily aimed at reducing environmental pollution, ensuring the reduction of operating costs and the production of industrial products based on waste-free production, the active introduction of highly environmentally friendly and cost-effective modern technologies, equipment and materials. It is recommended to improve the technological line of wastewater treatment of the enterprise.
Актуальность задачи анализа пожарной опасности электрооборудования объектов теплоэнергетического комплекса
Authors: Р.В. Кибус , А.В. Чубарь , Е.Ю. Трояк
Published: November 2024

Рассмотрена актуальность задачи анализа пожарной опасности электрооборудования объектов теплоэнергетического комплекса. Представлен статистический анализ пожаров, возникающих в результате нарушения устройства и эксплуатации теплогенерирующих установок. Проведен обзор крупнейших пожаров на теплоэлектроцентралях за последние 10 лет. Определена доля пожаров на ТЭЦ, приходящихся на электрооборудование, а также распределительные устройства и кабельные линии

The relevance of the fire hazard analysis task of electrical equipment of the heat and power complex objects is considered. The statistical analysis of fires arising as a result of violation of the design and operation of heat generating plants is presented. The largest fires at heat and power plants over the past 10 years have been reviewed. The share of fires at the CHPPs accounted for electrical equipment, switchgears and cable lines
Вопросы интеграции взаимодействия образования, науки и практики в системе подготовки кадров в МЧС России
Authors: Л.В. Юшкова
Published: November 2024

Статья посвящена вопросам интеграции взаимодействия образования, науки и практики в контексте всеобъемлющей комплексной подготовки кадров для МЧС России, где основное внимание уделяется точкам соприкосновения всех элементов системы подготовки кадров, ее приоритетам в современных быстроменяющихся условиях и возрастающих внешних вызовов, ответы на которые по своей сути должны стать в плоскость приоритета квалификации специалиста сферы защиты населения и территорий от чрезвычайных ситуаций.

the article is devoted to the integration of the interaction of education, science and practice in the context of comprehensive integrated training for the Ministry of Emergency Situations of Russia, where the main attention is paid to the points of contact of all elements of the training system, its priorities in modern rapidly changing conditions and increasing external challenges, the answers to which, in essence, should be in the plane of the priority of the qualification of a specialist in the field of public protection and territories from emergency situations.
Подходы к оценке действий оперативной дежурной смены при реагировании на техногенные пожары
Authors: Е.В. Скочилов , С.А. Гилек , Н.В. Мартинович , К.А. Корнейчук
Published: November 2024

На основании существующих алгоритмов предложен вариант оценки действий оперативной дежурной службы при реагировании на техногенные пожары по каждому основному показателю, характеризующему качество работы центров управления в кризисных ситуациях, опираясь на логистическую функцию Харрингтона.

Based on the logistics function of Harrington, an assessment of the actions of the operational duty service in responding to man-made fires was carried out for each main indicator characterizing the quality of the work of control centers in crisis situations
Проблемы доведения прогнозной информации до территориальных подсистем единой государственной системы предупреждения и ликвидации чрезвычайных ситуаций
Authors: Ж.Р. Костюнина , Л.В. Юшкова
Published: November 2024

В статье проводится анализ проблемного поля информативно-прогнозной базы в области защиты населения и территорий от чрезвычайных ситуаций природного характера. Среди таких проблем выявлены авторами сложность иерархических коллизий информационного регулирования, с запараллеливанием ряда функций, не соответствие научным критериям использования прогнозной информации, актуализации терминологии и алгоритмов действий в случаях чрезвычайных ситуаций, адаптация нормативно-правового регулирования под конкретные регионы и ситуации.

The article analyzes the problem field of the informative and predictive base in the field of protection of the population and territories from natural emergencies. Among such problems, the authors have identified the complexity of hierarchical collisions of information regulation, with parallelization of a number of functions, non-compliance with scientific criteria for the use of predictive information, updating terminology and algorithms of actions in emergency situations, adaptation of regulatory regulation to specific regions and situations.
Пути совершенствования систем мониторинга лесных пожаров на территории Республики Тыва
Authors: И.Н. Двойцова , А.Г. Монгуш
Published: November 2024

Мониторинг лесных пожаров на территории Республики Тыва имеет важное значение. Целью проведения мониторинга является профилактика и предотвращение горения лесов, а также защита населенных пунктов и объектов инфраструктуры. В настоящей статье проведен сравнительный анализ систем мониторинга лестных пожаров, предложены пути совершенствования мониторинга территорий.

Wildfire monitoring in the Republic of Tyva is extremely important. The purpose of the monitoring is prevention and avoidance of wildfires as well as protection of localities and infrastructure. In this article, the analysis of monitoring systems for wildfires is conducted and proposed ways to improve monitoring of territories.
Полимерные материалы: классификация и методы пожарно-технического исследования
Authors: А.А. Субраков , Е.С. Кабакова
Published: November 2024

В статье рассмотрена классификация полимерных материалов. Можно отметить, что полимерные материалы широко применяются во многих областях человеческой деятельности, удовлетворяя потребности различных отраслей промышленности, сельского хозяйства, медицины, культуры и быта. В связи с этим стоит отметить что полимеры обладают высокой горючестью. Показано, что основными методами исследования полимеров в целях пожарно-технической экспертизы являются методы термического анализа.

The article discusses the classification of polymer materials. It can be noted that polymer materials are widely used in many areas of human activity, satisfying the needs of various industries, agriculture, medicine, culture and everyday life. In this regard, it is worth noting that polymers are highly flammable. It is shown that the main methods of studying polymers for the purposes of fire-technical examination are thermal analysis methods.
Уровень пожарной безопасности в лечебных учреждениях на территории Российской Федерации
Authors: Н.Н. Назаров , Л.В. Долгушина
Published: November 2024

Рассмотрены вопросы пожарной безопасности в лечебных учреждениях Российской Федерации. Приведены сведения по пожарам, произошедшим в лечебных учреждениях на территории Российской Федерации за последние десять лет с 2012 по 2021 годы.

Fire safety issues in medical institutions of the Russian Federation were considered. Information on fires that occurred in medical institutions on the territory of the Russian Federation over the past ten years from
Возможные пути совершенствования системы обеспечения пожарной защиты радиотелевизионного передающего центра (РТПЦ)
Authors: М.В. Шевчук , Л.В. Долгушина
Published: November 2024

В статье рассматривается комплексная проблема повышения пожарной защиты радиотелевизионного предающего центра (РТПЦ). Акцентируется внимание на конструктивных особенностях объекта, обуславливающих электрических и неэлектрические причины пожаров. Предпринята попытка научного осмысления повышения мер пожарной защиты с учетом практико-ориентированного подхода, повышения профессионализма персонала РТПЦ. Приводятся примеры новых средств раннего обнаружения возгорания и обоснование применения газовых автоматических средств пожаротушения.

The article examines the complex problem of increasing fire protection of a radio-television transmission center (RTTC). Attention is focused on the design features of the facility that determine electrical and non-electrical causes of fires. An attempt has been made to scientifically comprehend the increase in fire protection measures, taking into account a practice-oriented approach, increasing the professionalism of the RTTC personnel. Examples of new means of early fire detection and justification for the use of gas automatic fire extinguishing means are given
Развитие экологической безопасности городской среды на примере комплексной системы обращения с твердыми коммунальными отходами на территории Ямало-Ненецкого автономного округа в рамках национального проекта «экология»
Authors: Д.С. Капустина , К.А. Кузнецова , Н.С. Изупов
Published: November 2024

Развитие экологической безопасности городской среды. Анализ сферы переработки отходов во вторичное сырье в Российской Федерации. Предотвращение вредного воздействия отходов на здоровье человека и окружающую среду, путем формирования комплексной системы обращения с твердыми коммунальными отходами на примере Ямало-Ненецкого автономного округа в рамках национального проекта «Экология».

Development of ecological safety of the urban environment. Analysis of the sphere of waste processing into secondary raw materials in the Russian Federation. Prevention of the harmful effects of waste on human health and the environment through the formation of an integrated system for handling municipal solid waste on the example of the Yamalo-Nenets Autonomous Okrug within the framework of the national project «Ecology».
Разработка способа предупреждения возникновения пожаров от больших переходных сопротивлений в электрических розетках
Authors: А.С. Горбунов , А.И. Анфиногенов
Published: November 2024

Разработан способ для предупреждения пожаров, возникающих от теплового проявления электрического тока при больших переходных сопротивлениях в электрических розетках. Предложена схема реализации установки для обнаружения и предотвращения пожара в электрических розетках.

A method has been developed to prevent fires arising from the thermal manifestation of electric current at high transient resistances in electrical outlets. A scheme for implementing an installation for detecting and preventing fire in electrical outlets is proposed.