bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 1 from Combined Administration of Rituximab and ON 013105 Induces Apoptosis in Mantle Cell Lymphoma Cells and Reduces Tumor Burden in a Mouse Model of Mantle Cell Lymphoma
Authors: Prasad Anil , Shrivastava Ashutosh , Papadopoulos Evangelos , Kuzontkoski Paula M. , Reddy M.V. Ramana , Gillum Amanda M. , Kumar Ramesh , Reddy E. Premkumar , Groopman Jerome E.
Published: April 2023

PDF file - 619K, Pharmacokinetic analysis of ON 013105 in mice after various routes of drug delivery
Supplementary Figures 1 - 8 from Transient Activation of Hedgehog Pathway Rescued Irradiation-Induced Hyposalivation by Preserving Salivary Stem/Progenitor Cells and Parasympathetic Innervation
Authors: Hai Bo , Qin Lizheng , Yang Zhenhua , Zhao Qingguo , Shangguan Lei , Ti Xinyu , Zhao Yanqiu , Kim Sangroh , Rangaraj Dharanipathy , Liu Fei
Published: April 2023

PDF file - 2605K, Fig. S1. X-gal staining of SMG sections from Ptch1-lacZ mice non-treated (NT), 7 days after ligation of main excretory ducts or IR. Fig. S2. 7 days of Dox treatment did not rescue IR-induced hyposalivation in female KrtrtTA/ tetO-Shh mice and male wild type mice. (A) Relative saliva flow rate. (B) Relative expression of acinar markers Aqp5 and Chrm3 determined by qRT-PCR. Fig. S3. Transient Hh activation has no long-term effect on percentage of putative salivary stem/progenitor cells. Fig. S4. Effects of transient Hh activation on proliferation and IR-induced apoptosis of SMG cells. Fig. S5. Co-expression of makers for salivary stem/progenitor cells with Hh target genes. Fig. S6. Activation of Hh pathway in female mouse SMGs by SAG. Fig. S7. Morphology of cultured human salivary epithelial cells. Fig. S8. Effects of retrograde Shh gene transfer into SMGs on expression of Hh target genes and SCC VII tumor growth.
Supplementary Tables 1 - 7 from Steroidogenic Germline Polymorphism Predictors of Prostate Cancer Progression in the Estradiol Pathway
Authors: Lévesque Éric , Laverdière Isabelle , Audet-Walsh Étienne , Caron Patrick , Rouleau Mélanie , Fradet Yves , Lacombe Louis , Guillemette Chantal
Published: April 2023

PDF file - 146KB, Supplementary Table 1. Genotype Frequencies of Polymorphisms in SULT2B1 and their Association with Biochemical Recurrence in 526 Cases with Localized Prostate Cancer. Supplementary Table 2. Genotype Frequencies of Polymorphisms in COMT and their Association with Biochemical Recurrence in 526 Cases with Localized Prostate Cancer. Supplementary Table 3. Genotype Frequencies of Polymorphisms in CYP1B1 and their Association with Biochemical Recurrence in 526 Cases with Localized Prostate Cancer. Supplementary Table 4. Genotype Frequencies of Polymorphisms in NQO1 and their Association with Biochemical Recurrence in 526 Cases with Localized Prostate Cancer. Supplementary Table 5. Genotype Frequencies of Polymorphisms in NQO2 and their Association with Biochemical Recurrence in 526 Cases with Localized Prostate Cancer. Supplementary Table 6. Association of SNPs with Prostate Cancer Progression for 213 Patients with Locally Advanced Prostate Cancer. Supplementary Table 7. Association of SNPs with the Overall Survival of 213 Patients with Locally Advanced Prostate Cancer.
Supplementary Figure 6 from Targeting of NAD Metabolism in Pancreatic Cancer Cells: Potential Novel Therapy for Pancreatic Tumors
Authors: Chini Claudia C.S. , Guerrico Anatilde M. Gonzalez , Nin Veronica , Camacho-Pereira Juliana , Escande Carlos , Barbosa Maria Thereza , Chini Eduardo N.
Published: April 2023

PDF file - 141K, mRNA expression in tumor tissues and pancreatic cell lines.
Supplementary Tables from Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 (OCT1)
Authors: Nies Anne T. , Schaeffeler Elke , van der Kuip Heiko , Cascorbi Ingolf , Bruhn Oliver , Kneba Michael , Pott Christiane , Hofmann Ute , Volk Christopher , Hu Shuiying , Baker Sharyn D. , Sparreboom Alex , Ruth Peter , Koepsell Hermann , Schwab Matthias
Published: April 2023

PDF file 64K, Supplementary Table S1. Overview of conflicting reports regarding the importance of OCT1 genetics, OCT1 expression, or cellular imatinib uptake for imatinib pharmacokinetics and response Supplementary Table S2. Multiple reaction monitoring transitions and MS parameters for determination of imatinib, N-desmethyl imatinib and their internal standards with LC-MS-MS Supplementary Table S3. Characteristics of SLC family members whose mRNA expression has been quantified by real-time PCR in the present study
Supplementary Figure 2 from Targeting of NAD Metabolism in Pancreatic Cancer Cells: Potential Novel Therapy for Pancreatic Tumors
Authors: Chini Claudia C.S. , Guerrico Anatilde M. Gonzalez , Nin Veronica , Camacho-Pereira Juliana , Escande Carlos , Barbosa Maria Thereza , Chini Eduardo N.
Published: April 2023

PDF file - 69K, Effect of FK866 on cell viability of SU86.86, Panc04.03, and HPDE pancreatic cells.
Supplementary Methods from Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 (OCT1)
Authors: Nies Anne T. , Schaeffeler Elke , van der Kuip Heiko , Cascorbi Ingolf , Bruhn Oliver , Kneba Michael , Pott Christiane , Hofmann Ute , Volk Christopher , Hu Shuiying , Baker Sharyn D. , Sparreboom Alex , Ruth Peter , Koepsell Hermann , Schwab Matthias
Published: April 2023

PDF file 65K, Supplementary methods including chemicals, generation of a cell line expressing OCT1 variant p.V408, transport studies using oocytes and cell lines, LC-MS-MS analysis of imatinib, RNA isolation and quantification, shRNA knockdown, flow cytometry and confocal laser scanning microscopy
Supplementary Figure 1 from Targeting of NAD Metabolism in Pancreatic Cancer Cells: Potential Novel Therapy for Pancreatic Tumors
Authors: Chini Claudia C.S. , Guerrico Anatilde M. Gonzalez , Nin Veronica , Camacho-Pereira Juliana , Escande Carlos , Barbosa Maria Thereza , Chini Eduardo N.
Published: April 2023

PDF file - 69K, Effect of FK866 treatment on respiratory parameters of intact pancreatic cancer cells.
Supplementary Table 7 from Sequential Binary Gene Ratio Tests Define a Novel Molecular Diagnostic Strategy for Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Richards William G. , Yeap Beow Y. , Coleman Melissa H. , Sugarbaker Peter E. , Chirieac Lucian R. , Wang Yaoyu E. , Quackenbush John , Jensen Roderick V. , Bueno Raphael
Published: April 2023

XLSX file - 196K, List of the enriched functional terms for the analysis Epithelioid MPM vs. Sarcomatoid MPM.
Supplementary Table 5 from Sequential Binary Gene Ratio Tests Define a Novel Molecular Diagnostic Strategy for Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Richards William G. , Yeap Beow Y. , Coleman Melissa H. , Sugarbaker Peter E. , Chirieac Lucian R. , Wang Yaoyu E. , Quackenbush John , Jensen Roderick V. , Bueno Raphael
Published: April 2023

XLSX file - 34K, List of the enriched functional terms for for the analysis MPM vs. other tumor types.
Supplementary Methods from Sequential Binary Gene Ratio Tests Define a Novel Molecular Diagnostic Strategy for Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Richards William G. , Yeap Beow Y. , Coleman Melissa H. , Sugarbaker Peter E. , Chirieac Lucian R. , Wang Yaoyu E. , Quackenbush John , Jensen Roderick V. , Bueno Raphael
Published: April 2023

PDF file - 53K, Identification of Diagnostic Molecular Markers and Data Analysis, Real-Time Quantitative PCR Results, Hierarchical clustering analysis.
Supplementary Figure 2 from Putative Predictive Biomarkers of Survival in Patients with Metastatic Pancreatic Adenocarcinoma Treated with Gemcitabine and Ganitumab, an IGF1R Inhibitor
Authors: McCaffery Ian , Tudor Yanyan , Deng Hongjie , Tang Rui , Suzuki Samuel , Badola Sunita , Kindler Hedy L. , Fuchs Charles S. , Loh Elwyn , Patterson Scott D. , Chen Li , Gansert Jennifer L.
Published: April 2023

PDF - 26K, Receiver Operator Characteristic Analysis for circulating biomarkers.
Supplementary Figures 1 - 8 from Reversal of Acquired Drug Resistance in FLT3-Mutated Acute Myeloid Leukemia Cells via Distinct Drug Combination Strategies
Authors: Zhang Weiguo , Gao Chen , Konopleva Marina , Chen Ye , Jacamo Rodrigo O. , Borthakur Gautam , Cortes Jorge E. , Ravandi Farhad , Ramachandran Abhijit , Andreeff Michael
Published: April 2023

PDF file - 468K, S1. Sorafenib-resistant murine AML (Ba/F3-ITD-Res) and parental cells (Ba/F3-ITD) were treated with indicated concentrations of sorafenib for 72 hours. Cell apoptosis induction was analyzed by measuring the percentage of annexin V-positive cells using flow cytometry. S2. Ba/F3-D835G, Ba/F3-D835Y and Ba/F3-FLT3 wild type cells were treated with crenolanib for 72 hours and their EC50s for apoptosis induction were determined by measuring percentage of annexin V-positive cells using flow cytometry. S3. Isobologram and combination index (CI) analyses were performed on sorafenib resistant cells after 48 hours combination treatment with crenolanib and sorafenib . S4. Isobologram and combination index (CI) analyses were performed on sorafenib resistant cells Ba/F3-ITD+676/842 after 48 hours combination treatment with vary combination strategies of type I and type II tyrosine kinase inhibitors. S5. Ba/F3-FLT3 wild type cells were treated with vary combination strategies of type I and type II tyrosine kinase inhibitors for 48 hours and apoptosis induction were determined by measuring percentage of annexin V-positive cells using flow cytometry. Creno: crenolanib; sora: sorafenib; PKC: PKC412; MLN: MLN518. S6. Normal bone marrow cells were exposed to indicated agents for 48 hours and apoptosis induction was determined by measuring the percentage of Annexin V-positive cells using flow cytometry. S7. FLT3 wild type AML patient blasts were exposed to crenolanib and/or sorafenib at physiologically achievable concentrations (i.e. Crenolanib @ 2 microM and sorafenib @ 5 microM) for 48 hours and apoptosis induction was determined by measuring the percentage of Annexin V-positive cells by gating CD33/CD34 positive population using flow cytometry. * Specific apoptosis (%) was calculated as follow: 100 X (drug-induced apoptosis − spontaneous apoptosis)/(100 − spontaneous apoptosis). S8. Sorafenib-resistan cells Ba/F3-ITD+676/842 were cultured in normoxic (21% oxygen) or hypoxic (1% oxygen) condition in the presence/absence of mesenchymal stem cells (MSC) feeder for 6 hours and phosphorylation levels of FLT3 and its downstream signaling ERK and AKT were determined using Western blotting.
Supplementary Figure 5 from Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance
Authors: de Haart Sanne J. , van de Donk Niels W.C.J. , Minnema Monique C. , Huang Julie H. , Aarts-Riemens Tineke , Bovenschen Niels , Yuan Huipin , Groen Richard W.J. , McMillin Douglas W. , Jakubikova Jana , Lokhorst Henk M. , Martens Anton C. , Mitsiades Constantine S. , Mutis Tuna
Published: April 2023

Supplementary Figure 5 - PDF file 41K, Bortezomib does not improve the CTL mediated lysis of Fas negative L363 cellsL3L3 reactive CD8+CTLs were incubated at the indicated effector to target ratios with luc-transduced L3L3 cells alone or in the presence of various dilutions of bortezomib. The CTL mediated and bortezomib mediated lysis of L3L3 cells was determined after 48 hours by BLI. Results are depicted as % surviving cells using the triplicate cultures without T cells and bortezomib as the 100% survival control
Supplementary Tables from Uncovering the Molecular Secrets of Inflammatory Breast Cancer Biology: An Integrated Analysis of Three Distinct Affymetrix Gene Expression Datasets
Authors: Van Laere Steven J. , Ueno Naoto T. , Finetti Pascal , Vermeulen Peter , Lucci Anthony , Robertson Fredika M. , Marsan Melike , Iwamoto Takayuki , Krishnamurthy Savitri , Masuda Hiroko , van Dam Peter , Woodward Wendy A. , Viens Patrice , Cristofanilli Massimo , Birnbaum Daniel , Dirix Luc , Reuben James M. , Bertucci François
Published: April 2023

Supplementary Tables XLS file - 236K, Supplementary Table 1: Comparison of ER- and ErbB2-status determined using gene expression profiling and immunohistochemistry Supplementary Table 2: Validation of the algorithm to identify transcription factor activation Supplementary Table 3: Description of the public nIBC data sets Supplementary Table 4: Molecular data of IBC and nIBC samples Supplementary Table 5: List of 491 probe sets differentially expressed between IBC and nIBC samples in a molecular subtype-independent manner Supplementary Table 6: IPA analysis of the list of 443 unique genes differentially expressed between IBC and nIBC Supplementary Table 7: Networks identified by IPA analysis of the list of 443 unique genes differentially expressed between IBC and nIBC Supplementary Table 8: Uni- and multivariate analyses for DMFS in the public pooled nIBC data set
Supplementary Data File and Legend from Uncovering the Molecular Secrets of Inflammatory Breast Cancer Biology: An Integrated Analysis of Three Distinct Affymetrix Gene Expression Datasets
Authors: Van Laere Steven J. , Ueno Naoto T. , Finetti Pascal , Vermeulen Peter , Lucci Anthony , Robertson Fredika M. , Marsan Melike , Iwamoto Takayuki , Krishnamurthy Savitri , Masuda Hiroko , van Dam Peter , Woodward Wendy A. , Viens Patrice , Cristofanilli Massimo , Birnbaum Daniel , Dirix Luc , Reuben James M. , Bertucci François
Published: April 2023

Supplementary Data File and Legend PDF file - 113K, Supplementary Data File and legend
Supplementary Figure Legend from Inhibition of NF-κB–Mediated Signaling by the Cyclin-Dependent Kinase Inhibitor CR8 Overcomes Prosurvival Stimuli to Induce Apoptosis in Chronic Lymphocytic Leukemia Cells
Authors: Cosimo Emilio , McCaig Alison M. , Carter-Brzezinski Luke J.M. , Wheadon Helen , Leach Michael T. , Le Ster Karine , Berthou Christian , Durieu Emilie , Oumata Nassima , Galons Hervé , Meijer Laurent , Michie Alison M.
Published: April 2023

PDF file - 88K
Supplementary Table 3 from Identification of FGFR4 as a Potential Therapeutic Target for Advanced-Stage, High-Grade Serous Ovarian Cancer
Authors: Zaid Tarrik M. , Yeung Tsz-Lun , Thompson Melissa S. , Leung Cecilia S. , Harding Tom , Co Ngai-Na , Schmandt Rosie S. , Kwan Suet-Ying , Rodriguez-Aguay Cristian , Lopez-Berestein Gabriel , Sood Anil K. , Wong Kwong-Kwok , Birrer Michael J. , Mok Samuel C.
Published: April 2023

PDF file - 2689K, Common differentially expressed genes in both OVCA432 and SKOV3 cells transfected with the FGFR4-specific siRNAs Hs_FGFR4_5 and Hs_FGFR4_6
Supplementary Figure Legend from Identification of FGFR4 as a Potential Therapeutic Target for Advanced-Stage, High-Grade Serous Ovarian Cancer
Authors: Zaid Tarrik M. , Yeung Tsz-Lun , Thompson Melissa S. , Leung Cecilia S. , Harding Tom , Co Ngai-Na , Schmandt Rosie S. , Kwan Suet-Ying , Rodriguez-Aguay Cristian , Lopez-Berestein Gabriel , Sood Anil K. , Wong Kwong-Kwok , Birrer Michael J. , Mok Samuel C.
Published: April 2023

PDF file - 78K
Supplementary Figure 7 from Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair
Authors: Wei Dongping , Parsels Leslie A. , Karnak David , Davis Mary A. , Parsels Joshua D. , Marsh Amanda C. , Zhao Lili , Maybaum Jonathan , Lawrence Theodore S. , Sun Yi , Morgan Meredith A.
Published: April 2023

PDF file - 167K, LB100 leads to persistent radiation-induced DNA damage.
Supplementary Materials and Methods, Figure Legends, Tables 1 - 9 from Identification of miR-133b and RB1CC1 as Independent Predictors for Biochemical Recurrence and Potential Therapeutic Targets for Prostate Cancer
Authors: Li Xia , Wan Xuechao , Chen Hongbing , Yang Shu , Liu Yiyang , Mo Wenjuan , Meng Delong , Du Wenting , Huang Yan , Wu Hai , Wang Jingqiang , Li Tao , Li Yao
Published: April 2023

PDF file - 183KB, Table S1. Correlation between miR-133b expression and RB1CC1 protein level and clinicopathologic features in prostate cancer patients after radical prostatectomy (RP). Table S2. 5-year biochemical recurrence (BCR)-free survival rates and mean BCR-free time for negative and positive miR-133b expression (a) and RB1CC1 expression (b) groups of prostate cancer patients after RP. Table S3. Sequences of synthetic oligonucleotides. Table S4. Primers used for real-time PCR amplification. Table S5. Locations and primer pairs for candidate AREs of miR-133b and negative control (a region of the DNA adjacent to miR-133b gene without a putative ARE). Table S6. Primers used for positive and negative DNA controls of ChIP assay. Table S7. Primers used for cloning the wild-type and mutation of 3'-UTR of RB1CC1 gene into pGL3-promoter Luciferase vector downstream of the Luciferase gene. Table S8. Pearson's rank correlation coefficient analysis. Table S9. Spearman's rank correlation coefficient analysis.
Supplementary Figure 3 from Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair
Authors: Wei Dongping , Parsels Leslie A. , Karnak David , Davis Mary A. , Parsels Joshua D. , Marsh Amanda C. , Zhao Lili , Maybaum Jonathan , Lawrence Theodore S. , Sun Yi , Morgan Meredith A.
Published: April 2023

PDF file - 69K, LB100 decreases cell survival in a concentration dependent manner.
Supplementary Figure 3 from Identification of miR-133b and RB1CC1 as Independent Predictors for Biochemical Recurrence and Potential Therapeutic Targets for Prostate Cancer
Authors: Li Xia , Wan Xuechao , Chen Hongbing , Yang Shu , Liu Yiyang , Mo Wenjuan , Meng Delong , Du Wenting , Huang Yan , Wu Hai , Wang Jingqiang , Li Tao , Li Yao
Published: April 2023

PDF file - 254KB, Quantitative analyses of cell apoptosis in LNCaP and PC-3 cells and the transfection efficiency of cell apoptosis assays in these two cell lines.
Supplementary Figure 1 from Identification of miR-133b and RB1CC1 as Independent Predictors for Biochemical Recurrence and Potential Therapeutic Targets for Prostate Cancer
Authors: Li Xia , Wan Xuechao , Chen Hongbing , Yang Shu , Liu Yiyang , Mo Wenjuan , Meng Delong , Du Wenting , Huang Yan , Wu Hai , Wang Jingqiang , Li Tao , Li Yao
Published: April 2023

PDF file - 167KB, The expression of PSA and KLK2 in DHT treated LNCaP cells and the transfection efficiency of cell proliferation in prostate cancer cells.
Supplementary Table 3 from Proteomic Characterization of Breast Cancer Xenografts Identifies Early and Late Bevacizumab-Induced Responses and Predicts Effective Drug Combinations
Authors: Lindholm Evita M. , Krohn Marit , Iadevaia Sergio , Kristian Alexandr , Mills Gordon B. , Mælandsmo Gunhild M. , Engebraaten Olav
Published: April 2023

PDF file - 37K, Supplementary Table 3: Protein regulation in basal‐like tumors after bevacizumab and BEZ235 treatment.
Supplementary Table 2 from Therapeutic Potential of HSP90 Inhibition for Neurofibromatosis Type 2
Authors: Tanaka Karo , Eskin Ascia , Chareyre Fabrice , Jessen Walter J. , Manent Jan , Niwa-Kawakita Michiko , Chen Ruihong , White Cory H. , Vitte Jeremie , Jaffer Zahara M. , Nelson Stanley F. , Rubenstein Allan E. , Giovannini Marco
Published: April 2023

Supplementary Table 2 - XLS file 40K, qPCR validation of transcriptome
Supplementary Figure 4 from Phase I Clinical Trial of Mixed Bacterial Vaccine (Coley's Toxins) in Patients with NY-ESO-1 Expressing Cancers: Immunological Effects and Clinical Activity
Authors: Karbach Julia , Neumann Antje , Brand Kathrin , Wahle Claudia , Siegel Ekkehard , Maeurer Markus , Ritter Erika , Tsuji Takamasa , Gnjatic Sacha , Old Lloyd J. , Ritter Gerd , Jäger Elke
Published: April 2023

PDF file, 39K, Reactivation of cytokine response by further MBV administration after a MBV treatment-free period.
Supplementary Figure 7 from Electrocardiographic Studies of Romidepsin Demonstrate Its Safety and Identify a Potential Role for KATP Channel
Authors: Noonan Anne M. , Eisch Robin A. , Liewehr David J. , Sissung Tristan M. , Venzon David J. , Flagg Thomas P. , Haigney Mark C. , Steinberg Seth M. , Figg William D. , Piekarz Richard L. , Bates Susan E.
Published: April 2023

Supplementary Figure 7 - PDF file 317K, Changes in mean heart rate occurring during cycle 1 days 1, 8 and 15 grouped by baseline heart rate
Supplementary Figure 3 from Electrocardiographic Studies of Romidepsin Demonstrate Its Safety and Identify a Potential Role for KATP Channel
Authors: Noonan Anne M. , Eisch Robin A. , Liewehr David J. , Sissung Tristan M. , Venzon David J. , Flagg Thomas P. , Haigney Mark C. , Steinberg Seth M. , Figg William D. , Piekarz Richard L. , Bates Susan E.
Published: April 2023

Supplementary Figure 3 - PDF file 62K, Changes in mean heart rate during cycles 1 when patients taking betablockers were excluded
Supplementary Figure 2 from Electrocardiographic Studies of Romidepsin Demonstrate Its Safety and Identify a Potential Role for KATP Channel
Authors: Noonan Anne M. , Eisch Robin A. , Liewehr David J. , Sissung Tristan M. , Venzon David J. , Flagg Thomas P. , Haigney Mark C. , Steinberg Seth M. , Figg William D. , Piekarz Richard L. , Bates Susan E.
Published: April 2023

Supplementary Figure 2 - PDF file 260K, Changes in mean heart rate occurring during cycle 1 days 1, 8 and 15 grouped by baseline heart rate
Supplementary Tables 1 - 5 from Targeting the NF-κB and mTOR Pathways with a Quinoxaline Urea Analog That Inhibits IKKβ for Pancreas Cancer Therapy
Authors: Radhakrishnan Prakash , Bryant Vashti C. , Blowers Elizabeth C. , Rajule Rajkumar N. , Gautam Nagsen , Anwar Muhammad M. , Mohr Ashley M. , Grandgenett Paul M. , Bunt Stephanie K. , Arnst Jamie L. , Lele Subodh M. , Alnouti Yazen , Hollingsworth Michael A. , Natarajan Amarnath
Published: April 2023

PDF file - 53K, Table S1: Pancreatic cancer cell growth inhibition by 13-197; Table S2: % Neutrophils upon prolonged treatment with 13-197; Table S3: Metastases in mice treated with 13-197; Table S4: Immunohistochemical analysis of tumor samples; Table S5: Inflammation and Necrosis in tumor tissues
Supplementary Figure 1 from Downregulation of FOXO3a Promotes Tumor Metastasis and Is Associated with Metastasis-Free Survival of Patients with Clear Cell Renal Cell Carcinoma
Authors: Ni Dong , Ma Xin , Li Hong-Zhao , Gao Yu , Li Xin-Tao , Zhang Yu , Ai Qing , Zhang Peng , Song Er-Lin , Huang Qing-Bo , Fan Yang , Zhang Xu
Published: April 2023

PDF file - 143KB, Pathway analysis based on KEGG, Biocarta, and Reatome database.
Supplementary Figure 4 from A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors
Authors: Rodon Jordi , Tawbi Hussein A. , Thomas Anne L. , Stoller Ronald G. , Turtschi Christian P. , Baselga Jose , Sarantopoulos John , Mahalingam Devalingam , Shou Yaping , Moles Melissa A. , Yang Lin , Granvil Camille , Hurh Eunju , Rose Kristine L. , Amakye Dereck D. , Dummer Reinhard , Mita Alain C.
Published: April 2023

PDF file - 97K, Reduction in glioma-associated oncogene homolog 1 in patients with available tumor and matching skin specimens.
Supplementary Figure 2 from An In Vivo Immunotherapy Screen of Costimulatory Molecules Identifies Fc-OX40L as a Potent Reagent for the Treatment of Established Murine Gliomas
Authors: Murphy Katherine A. , Lechner Melissa G. , Popescu Flavia E. , Bedi Jessica , Decker Stacy A. , Hu Peisheng , Erickson Jami R. , O'Sullivan M. Gerard , Swier Lauryn , Salazar Andres M. , Olin Michael R. , Epstein Alan L. , Ohlfest John R.
Published: April 2023

PDF file, 210K, In vitro activity assay of costimulatory molecules tested.
Supplementary Table 1 from Systematic Kinome shRNA Screening Identifies CDK11 (PITSLRE) Kinase Expression Is Critical for Osteosarcoma Cell Growth and Proliferation
Authors: Duan Zhenfeng , Zhang Jianming , Choy Edwin , Harmon David , Liu Xianzhe , Nielsen Petur , Mankin Henry , Gray Nathanael S. , Hornicek Francis J.
Published: April 2023

PDF file, 43K, Lentiviral shRNA sequences target CDK11 (PITSLRE).
Supplementary Figure 4 from Nupr1-Aurora Kinase A Pathway Provides Protection against Metabolic Stress-Mediated Autophagic-Associated Cell Death
Authors: Hamidi Tewfik , Cano Carla E. , Grasso Daniel , Garcia Maria Noé , Sandi Maria José , Calvo Ezequiel L. , Dagorn Jean-Charles , Lomberk Gwen , Urrutia Raul , Goruppi Sandro , Carracedo Arkaitz , Velasco Guillermo , Iovanna Juan L.
Published: April 2023

PDF file, 222K, Protective role of Nupr1 and AURKA in Panc-1 cells.
Supplementary Figure 2 from Systematic Kinome shRNA Screening Identifies CDK11 (PITSLRE) Kinase Expression Is Critical for Osteosarcoma Cell Growth and Proliferation
Authors: Duan Zhenfeng , Zhang Jianming , Choy Edwin , Harmon David , Liu Xianzhe , Nielsen Petur , Mankin Henry , Gray Nathanael S. , Hornicek Francis J.
Published: April 2023

PDF file, 38K, Dose-dependent effect of siRNA targeting CDK11 in osteosarcoma cell lines KHOS and U-2OS.
Supplementary Figure 4 from Stromal Responses among Common Carcinomas Correlated with Clinicopathologic Features
Authors: Chen Julia L-Y. , Espinosa Iñigo , Lin Albert Y. , Liao Olivia Y-W. , van de Rijn Matt , West Robert B.
Published: April 2023

PDF file, 393K, The results of the survival analysis of the lung tumors in lung cancer datasets including caArray-beer-00153 (Supp Fig4A), GSE4573 (Supp Fig4B), GSE10445 (Supp Fig4C), GSE10245 (Supp Fig4D) and GSE11969 (Supp Fig4E).
Supplementary Table 3 from TGF-β–Induced Upregulation of malat1 Promotes Bladder Cancer Metastasis by Associating with suz12
Authors: Fan Yu , Shen Bing , Tan Mingyue , Mu Xinyu , Qin Yan , Zhang Fang , Liu Yong
Published: April 2023

PDF file - 67K, siRNA Sequence in the study.
Supplemental Materials for Smith and Houghton from A Proposal Regarding Reporting of In Vitro Testing Results
Authors: Smith Malcolm A. , Houghton Peter
Published: April 2023

Supplemental Materials for Smith and Houghton (A Proposal Regarding Reporting of in Vitro Testing Results): References to justify specific statements made in the manuscript
Supplementary Methods from 18F-Fluorodeoxyglucose Positron Emission Tomography in the Management of Patients with Thymic Epithelial Tumors
Authors: Thomas Anish , Mena Esther , Kurdziel Karen , Venzon David , Khozin Sean , Berman Arlene W. , Choyke Peter , Szabo Eva , Rajan Arun , Giaccone Giuseppe
Published: April 2023

PDF file - 105K, Methodological details of 18F-FDG PET/CT image acquisition and analysis
Supplementary Methods from Temozolomide Does Not Impair Gene Therapy-Mediated Antitumor Immunity in Syngeneic Brain Tumor Models
Authors: Candolfi Marianela , Yagiz Kader , Wibowo Mia , Ahlzadeh Gabrielle E. , Puntel Mariana , Ghiasi Homayon , Kamran Neha , Paran Christopher , Lowenstein Pedro R. , Castro Maria G.
Published: April 2023

PDF file - 83K
Supplementary Figures from Relationships between LDH-A, Lactate, and Metastases in 4T1 Breast Tumors
Authors: Rizwan Asif , Serganova Inna , Khanin Raya , Karabeber Hazem , Ni Xiaohui , Thakur Sunitha , Zakian Kristen L. , Blasberg Ronald , Koutcher Jason A.
Published: April 2023

Supplementary Figures - PDF file 259K, Figure S1. Comparison of 4T1-WT, NC and KD9 cell lines. (A) Oxylite Oxygen Consumption Rate; (B) Reactive oxygen species (ROS); (C) mitochondria level; (D) Primary tumor (~ 100 mm3) lactate concentration. Figure S2. Histology of small (100 mm3) primary NC and KD9 tumors (A). Representative small tumors show similar features: a few small areas of necrosis (H&E) and reduced blood flow (Hoechst). Scale bar represents 5 mm. Cell Mitochondria (B). NC and KD9 cells were grown on the cover slips and stained for mitochondria by Mitotracker red CMXRos. Fig. S3. Primary orthotopic tumor growth and development of lung metastases. Three weeks after tumor inoculation, the mice were sacrificed and the primary tumor volume and weight, as well as lung weight (reflecting the presence of lung metastases) were measured in NC (n=6) and KD9 (n=6) tumor bearing animals Fig. S4. Western blot analysis of LDH-A expression: The absence of puromycin in the culture media results in a reappearance of LDH-A expression in KD9 cells growing in vitro (columns 3 and 5)
Supplementary Figure 7 from Temozolomide Does Not Impair Gene Therapy-Mediated Antitumor Immunity in Syngeneic Brain Tumor Models
Authors: Candolfi Marianela , Yagiz Kader , Wibowo Mia , Ahlzadeh Gabrielle E. , Puntel Mariana , Ghiasi Homayon , Kamran Neha , Paran Christopher , Lowenstein Pedro R. , Castro Maria G.
Published: April 2023

PDF file - 2644K, Effect of TMZ in combination with immunotherapy on the content of lymphocytes in the spleen.
Supplementary Figure 5 from Temozolomide Does Not Impair Gene Therapy-Mediated Antitumor Immunity in Syngeneic Brain Tumor Models
Authors: Candolfi Marianela , Yagiz Kader , Wibowo Mia , Ahlzadeh Gabrielle E. , Puntel Mariana , Ghiasi Homayon , Kamran Neha , Paran Christopher , Lowenstein Pedro R. , Castro Maria G.
Published: April 2023

PDF file - 1820K, Effect of TMZ on the number of circulating lymphocytes.
Supplementary Figures 4 - 8 from Predicting Response to Bevacizumab in Ovarian Cancer: A Panel of Potential Biomarkers Informing Treatment Selection
Authors: Collinson Fiona , Hutchinson Michelle , Craven Rachel A. , Cairns David A. , Zougman Alexandre , Wind Tobias C. , Gahir Narinder , Messenger Michael P. , Jackson Sharon , Thompson Douglas , Adusei Cybil , Ledermann Jonathan A. , Hall Geoffrey , Jayson Gordon C. , Selby Peter J. , Banks Rosamonde E.
Published: April 2023

PDF file - 963K, Supplementary Figure 4: Correlation between biomarkers investigated in validation cohort I; Supplementary Figure 5: Longitudinal patterns in AGP concentration in validation cohort I; Supplementary Figure 6. Prognostic and predictive potential of candidate biomarkers in validation cohort I; Supplementary Figure 7. Kaplan Meier estimates of the survival function showing prognostic and predictive ability of the biomarker index in validation cohort I; Supplementary Figure 8. Prognostic and predictive potential of individual elements of biomarker index in the combined validation cohort.
Supplementary Table 1 - 4 from Efficacy, Safety, Pharmacokinetics, and Biomarkers of Cediranib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study
Authors: Zhu Andrew X. , Ancukiewicz Marek , Supko Jeffrey G. , Sahani Dushyant V. , Blaszkowsky Lawrence S. , Meyerhardt Jeffrey A. , Abrams Thomas A. , McCleary Nadine Jackson , Bhargava Pankaj , Muzikansky Alona , Sheehan Susan , Regan Eileen , Vasudev Eamala , Knowles Michelle , Fuchs Charles S. , Ryan David P. , Jain Rakesh K. , Duda Dan G.
Published: April 2023

PDF file - 159K, Supplementary Table S1: Kinetics of plasma biomarkers and circulating progenitor cells (CPCs) at days 1 and/or 14 during the first cycle of daily 30mg cediranib monotherapy in advanced HCC patients. Supplementary Table S2: Analysis of correlation between pre-treatment and on-treatment changes (normalized to baseline values) in blood biomarkers and PK parameters after daily 30mg cediranib monotherapy in advanced HCC patients. Supplementary Table S3: Analysis of correlation between adverse effects (AEs) after daily 30mg cediranib monotherapy in advanced HCC patients with pre-treatment and on-treatment changes(normalized to baseline values) in blood biomarkers. Supplementary Table S4: Changes in hemoglobin after daily 30mg cediranib monotherapy in advanced HCC patients.
Supplementary Figure 2 from Human Regulatory T Cells Do Not Suppress the Antitumor Immunity in the Bone Marrow: A Role for Bone Marrow Stromal Cells in Neutralizing Regulatory T Cells
Authors: Guichelaar Teun , Emmelot Maarten E. , Rozemuller Henk , Martini Bianka , Groen Richard W.J. , Storm Gert , Lokhorst Henk M. , Martens Anton C. , Mutis Tuna
Published: April 2023

PDF file - 54K, Human Tregs allow GvT against murine lymphoma tumors. Human PBMC were infused alone or together with expanded human Tregs to treat immune deficient mice carrying murine Luciferase+ A20 lymphoma cells in the bone marrow. PBMC (n=10), PBMC + Treg (n=9), untreated control group (n=10) (A) Kaplan Meier survival curves of mice, which all were sacrificed due to paralysis ***, p<0.0005 ( Mantel Cox Log-Rank test). (B) The tumor load in different groups at two weeks after PBMC/Treg infusion Mean values are indicated . *** p <0.0005 (unpaired t test).
Supplementary Figure 1 from Human Regulatory T Cells Do Not Suppress the Antitumor Immunity in the Bone Marrow: A Role for Bone Marrow Stromal Cells in Neutralizing Regulatory T Cells
Authors: Guichelaar Teun , Emmelot Maarten E. , Rozemuller Henk , Martini Bianka , Groen Richard W.J. , Storm Gert , Lokhorst Henk M. , Martens Anton C. , Mutis Tuna
Published: April 2023

PDF file - 49K, Ex vivo expansion and suppressor capacity of Tregs. (A) Ex vivo expansion rate of CD4+CD25+ Tregs isolated from peripheral blood. (B) Suppressive activity of ex vivo cultured Tregs on CD4+CD25- effector T cells stimulated with CD3/CD28 expander beads. Ex vivo cultures and suppression assays were executed as indicated in the material and methods section. Presented data are representative of >5 individual Treg cultures from different donors. Error bars indicate the SEM of at least duplicate measurements. The expanded Treg cultures contained 70% +/- 3% Foxp3+ T cells which were also negative for CD127. The cultures also contained 4.5+/-3.6 % IL-17 producing cells as detected after stimulation with PMA/Ionomycin (see also ref 20)
Supplementary Figure 4 from The Prognostic Significance and Therapeutic Potential of Hedgehog Signaling in Intrahepatic Cholangiocellular Carcinoma
Authors: Tang Liang , Tan Ye-Xiong , Jiang Bei-Ge , Pan Yu-Fei , Li Shuang-Xi , Yang Guang-Zhen , Wang Min , Wang Qing , Zhang Jian , Zhou Wei-Ping , Dong Li-Wei , Wang Hong-Yang
Published: April 2023

PDF file - 132K, Silence of Gli1 inhibited cholangiocarcinoma cells growth in vitro and in vivo.
Supplementary Figure Legends, Table Legends from Differences in the Transcriptional Response to Fulvestrant and Estrogen Deprivation in ER-Positive Breast Cancer
Authors: Patani Neill , Dunbier Anita K. , Anderson Helen , Ghazoui Zara , Ribas Ricardo , Anderson Elizabeth , Gao Qiong , A'hern Roger , Mackay Alan , Lindemann Justin , Wellings Robert , Walker Jill , Kuter Irene , Martin Lesley-Ann , Dowsett Mitch
Published: April 2023

PDF file - 29KB
Supplementary Table 2 from Notch Pathway Activity Identifies Cells with Cancer Stem Cell–like Properties and Correlates with Worse Survival in Lung Adenocarcinoma
Authors: Hassan Khaled A. , Wang Luo , Korkaya Hasan , Chen Guoan , Maillard Ivan , Beer David G. , Kalemkerian Gregory P. , Wicha Max S.
Published: April 2023

PDF file - 90K, Notch pathway genes categorized based on function.
Supplementary Table S7 from Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors
Authors: Vrignaud Patricia , Sémiond Dorothée , Lejeune Pascale , Bouchard Hervé , Calvet Loreley , Combeau Cecile , Riou Jean-François , Commerçon Alain , Lavelle François , Bissery Marie-Christine
Published: April 2023

Supplementary Table S7 - PDF file 53K, Median tumor volumes � interquartile ranges following treatment with cabazitaxel and docetaxel in female nude mice bearing human breast UISO BCA-1 tumor xenografts
Supplementary Figure S3 from Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer
Authors: Zhang Geng , He Peijun , Tan Hanson , Budhu Anuradha , Gaedcke Jochen , Ghadimi B. Michael , Ried Thomas , Yfantis Harris G. , Lee Dong H. , Maitra Anirban , Hanna Nader , Alexander H. Richard , Hussain S. Perwez
Published: April 2023

Supplementary Figure S3 - PDF file 112K, Immunohistochemical staining of PNLIP in pancreatic tumors and adjacent nontumor tissue
Supplementary Figure S1 from Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer
Authors: Zhang Geng , He Peijun , Tan Hanson , Budhu Anuradha , Gaedcke Jochen , Ghadimi B. Michael , Ried Thomas , Yfantis Harris G. , Lee Dong H. , Maitra Anirban , Hanna Nader , Alexander H. Richard , Hussain S. Perwez
Published: April 2023

Supplementary Figure S1 - PDF file 115K, Gene expression of PNLIP, CLPS, PNLIRP1 and PNLIPRP2 in Panc1, MIApaca2 and non-tumorigenic hTERT-HPNE cell lines
Supplementary Table 1 from ETS2 Mediated Tumor Suppressive Function and MET Oncogene Inhibition in Human Non–Small Cell Lung Cancer
Authors: Kabbout Mohamed , Garcia Melinda M. , Fujimoto Junya , Liu Diane D. , Woods Denise , Chow Chi-Wan , Mendoza Gabriela , Momin Amin A. , James Brian P. , Solis Luisa , Behrens Carmen , Lee J. Jack , Wistuba Ignacio I. , Kadara Humam
Published: April 2023

Supplementary Table 1 - PDF file 57K, Clinicopathological information of the NSCLC tissue microarray specimens analyzed by IHC analysis
Supplementary Figure 5 from Network Analysis Identifies an HSP90-Central Hub Susceptible in Ovarian Cancer
Authors: Liu Hanqing , Xiao Fang , Serebriiskii Ilya G. , O'Brien Shane W. , Maglaty Marisa A. , Astsaturov Igor , Litwin Samuel , Martin Lainie P. , Proia David A. , Golemis Erica A. , Connolly Denise C.
Published: April 2023

PDF file - 172KB, HSP90-interacting proteins in ganetespib-treated cells and tumors.
Supplementary Video 4 from Rab25 Regulates Invasion and Metastasis in Head and Neck Cancer
Authors: Amornphimoltham Panomwat , Rechache Kamil , Thompson Jamie , Masedunskas Andrius , Leelahavanichkul Kantima , Patel Vyomesh , Molinolo Alfredo , Gutkind J. Silvio , Weigert Roberto
Published: April 2023

MOV file - 313K, Rab25 expression reduces protrusion at the plasma membrane
Supplementary Video 3 from Rab25 Regulates Invasion and Metastasis in Head and Neck Cancer
Authors: Amornphimoltham Panomwat , Rechache Kamil , Thompson Jamie , Masedunskas Andrius , Leelahavanichkul Kantima , Patel Vyomesh , Molinolo Alfredo , Gutkind J. Silvio , Weigert Roberto
Published: April 2023

MOV file - 313K, Intravital imaging of tumor cells migration
Supplementary Figure Legend from Phase II Trial of MEK Inhibitor Selumetinib (AZD6244, ARRY-142886) in Patients with BRAFV600E/K-Mutated Melanoma
Authors: Catalanotti Federica , Solit David B. , Pulitzer Melissa P. , Berger Michael F. , Scott Sasinya N. , Iyriboz Tunc , Lacouture Mario E. , Panageas Katherine S. , Wolchok Jedd D. , Carvajal Richard D. , Schwartz Gary K. , Rosen Neal , Chapman Paul B.
Published: April 2023

PDF file - 48K
Supplementary Figure 3 from Phase II Trial of MEK Inhibitor Selumetinib (AZD6244, ARRY-142886) in Patients with BRAFV600E/K-Mutated Melanoma
Authors: Catalanotti Federica , Solit David B. , Pulitzer Melissa P. , Berger Michael F. , Scott Sasinya N. , Iyriboz Tunc , Lacouture Mario E. , Panageas Katherine S. , Wolchok Jedd D. , Carvajal Richard D. , Schwartz Gary K. , Rosen Neal , Chapman Paul B.
Published: April 2023

PDF file - 6545K, Detection of a K57N MEK1 mutation in DNA from formalin-fixed paraffin-embedded tumor and matched normal tissue from one patient. Multiple reads from tumor-derived DNA (panel on left) show a GC transversion in 21% of reads. This indicates a lysineaspargine mutation in MEK1. No such mutation is detected in germline DNA (panel at right).
CCR Translation for This Article from Myeloid-Derived Suppressor Cells Predict Survival of Patients with Advanced Melanoma: Comparison with Regulatory T Cells and NY-ESO-1- or Melan-A–Specific T Cells
Authors: Weide Benjamin , Martens Alexander , Zelba Henning , Stutz Christina , Derhovanessian Evelyna , Di Giacomo Anna Maria , Maio Michele , Sucker Antje , Schilling Bastian , Schadendorf Dirk , Büttner Petra , Garbe Claus , Pawelec Graham
Published: April 2023

CCR Translation for This Article from Myeloid-Derived Suppressor Cells Predict Survival of Patients with Advanced Melanoma: Comparison with Regulatory T Cells and NY-ESO-1- or Melan-A–Specific T Cells
Supplementary Figure 1 from Hedgehog–GLI Signaling Inhibition Suppresses Tumor Growth in Squamous Lung Cancer
Authors: Huang Lingling , Walter Vonn , Hayes D. Neil , Onaitis Mark
Published: April 2023

PDF file - 574K, Analysis of human LSCC microarray data.
Supplementary Table 16 from Nonequivalent Gene Expression and Copy Number Alterations in High-Grade Serous Ovarian Cancers with BRCA1 and BRCA2 Mutations
Authors: George Joshy , Alsop Kathryn , Etemadmoghadam Dariush , Hondow Heather , Mikeska Thomas , Dobrovic Alexander , deFazio Anna , Smyth Gordon K. , Levine Douglas A. , Mitchell Gillian , Bowtell David D.
Published: April 2023

PDF file - 28K
Supplementary Methods from PI3K Pathway Dependencies in Endometrioid Endometrial Cancer Cell Lines
Authors: Weigelt Britta , Warne Patricia H. , Lambros Maryou B. , Reis-Filho Jorge S. , Downward Julian
Published: April 2023

Supplementary Methods - PDF file 28K, Supplementary Methods
Supplementary Figure Legend from HER2-Associated Radioresistance of Breast Cancer Stem Cells Isolated from HER2-Negative Breast Cancer Cells
Authors: Duru Nadire , Fan Ming , Candas Demet , Menaa Cheikh , Liu Hsin-Chen , Nantajit Danupon , Wen Yunfei , Xiao Kai , Eldridge Angela , Chromy Brett A. , Li Shiyong , Spitz Douglas R. , Lam Kit S. , Wicha Max S. , Li Jian Jian
Published: April 2023

PDF file - 112K
Supplementary Figure 3 from HER2-Associated Radioresistance of Breast Cancer Stem Cells Isolated from HER2-Negative Breast Cancer Cells
Authors: Duru Nadire , Fan Ming , Candas Demet , Menaa Cheikh , Liu Hsin-Chen , Nantajit Danupon , Wen Yunfei , Xiao Kai , Eldridge Angela , Chromy Brett A. , Li Shiyong , Spitz Douglas R. , Lam Kit S. , Wicha Max S. , Li Jian Jian
Published: April 2023

PDF file - 144K, FACS of irradiated MCF7 cells and xenograft tumors
Supplementary Figure 3 from Inactivation of the CDKN2A Tumor-Suppressor Gene by Deletion or Methylation Is Common at Diagnosis in Follicular Lymphoma and Associated with Poor Clinical Outcome
Authors: Alhejaily Abdulmohsen , Day Andrew G. , Feilotter Harriet E. , Baetz Tara , LeBrun David P.
Published: April 2023

PDF file - 49K, Overall survival according to pRb expression as determined by visual scoring of immunohistochemically stained slides.
Supplementary Figure S1 from Ligand-Dependent Activation of EGFR in Follicular Dendritic Cells Sarcoma is Sustained by Local Production of Cognate Ligands
Authors: Vermi William , Giurisato Emanuele , Lonardi Silvia , Balzarini Piera , Rossi Elisa , Medicina Daniela , Bosisio Daniela , Sozzani Silvano , Pellegrini Wilma , Doglioni Claudio , Marchetti Antonio , Rossi Giulio , Pileri Stefano , Facchetti Fabio
Published: April 2023

Expression of EGFR by FDC and FRC on human lymph nodes.
Supplementary Table 4 from Next-Generation Sequencing of Translocation Renal Cell Carcinoma Reveals Novel RNA Splicing Partners and Frequent Mutations of Chromatin-Remodeling Genes
Authors: Malouf Gabriel G. , Su Xiaoping , Yao Hui , Gao Jianjun , Xiong Liangwen , He Qiuming , Compérat Eva , Couturier Jérôme , Molinié Vincent , Escudier Bernard , Camparo Philippe , Doss Denaha J. , Thompson Erika J. , Khayat David , Wood Christopher G. , Yu Willie , Teh Bin T. , Weinstein John , Tannir Nizar M.
Published: April 2023

XLSX file - 172K, List of genes that have been reported previously to be involved in translocations.
Supplementary Methods from Safety and Pharmacokinetics of Ganitumab (AMG 479) Combined with Sorafenib, Panitumumab, Erlotinib, or Gemcitabine in Patients with Advanced Solid Tumors
Authors: Rosen Lee S. , Puzanov Igor , Friberg Gregory , Chan Emily , Hwang Yuying C. , Deng Hongjie , Gilbert Jill , Mahalingam Devalingam , McCaffery Ian , Michael Shaunita A. , Mita Alain C. , Mita Monica M. , Mulay Marilyn , Shubhakar Poornima , Zhu Min , Sarantopoulos John
Published: April 2023

PDF file, 86KB.
Supplementary Figures 1 - 2 from PD-L1 Expression Is Characteristic of a Subset of Aggressive B-cell Lymphomas and Virus-Associated Malignancies
Authors: Chen Benjamin J. , Chapuy Bjoern , Ouyang Jing , Sun Heather H. , Roemer Margaretha G.M. , Xu Mina L. , Yu Hongbo , Fletcher Christopher D.M. , Freeman Gordon J. , Shipp Margaret A. , Rodig Scott J.
Published: April 2023

PDF file - 1425K, Figure S1. (A) Human placenta stained with the rabbit monoclonal anti-PD-L1 (original lot concentration of 0.22 mg/ml) and showing membrane staining of syncytiotrophoblasts and, (B) the same case stained with the mouse monoclonal anti-PD-L1 (original lot concentration of 0.65 mg/ml). (C) Human tonsil stained with rabbit anti-PD-L1 antibody (original lot concentration of 1.55 mg/ml) and, (D) stained with the rabbit anti-PD-L1 antibody (original lot concentration of 0.22 mg/ml) and, (E) stained with the mouse anti-PD-L1 antibody (original lot concentration of 0.65 mg/ml). Figure S2. (A-C) Case of classical Hodgkin lymphoma stained with (A) the rabbit anti-PD-L1 antibody (original lot concentration of 1.55 mg/ml), (B) the rabbit anti-PD-L1 antibody (original lot concentration of 0.22 mg/ml, and (C) the mouse anti-PD-L1 antibody (original lot concentration of 0.65 mg/ml). (E-F) Case of EBV-negative PTLD stained with (D) the rabbit anti-PD-L1 antibody (original lot concentration of 1.55 mg/ml), (E) the rabbit anti-PD-L1 antibody (original lot concentration of 0.22 mg/ml, and (F) the mouse anti-PD-L1 antibody (original lot concentration of 0.65 mg/ml).
Related Article from Imaging Tumor Sensitivity to a Bioreductive Prodrug: Two for the Price of One!
Authors: Brown J. Martin
Published: April 2023

Related Article from Imaging Tumor Sensitivity to a Bioreductive Prodrug: Two for the Price of One!
Table S8 from MicroRNA Array Analysis Finds Elevated Serum miR-1290 Accurately Distinguishes Patients with Low-Stage Pancreatic Cancer from Healthy and Disease Controls
Authors: Li Ang , Yu Jun , Kim Haeryoung , Wolfgang Christopher L. , Canto Marcia Irene , Hruban Ralph H. , Goggins Michael
Published: April 2023

Table S8 - XLSX file 13KB, Supplemental Table S8. Association between serum miR-1290 and miR-486-3p levels and clinicopathologic characteristics among patients undergoing resection of their primary pancreatic cancer
Supplementary Table S1 from NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases
Authors: Fogliatto Gianpaolo , Gianellini Laura , Brasca Maria G. , Casale Elena , Ballinari Dario , Ciomei Marina , Degrassi Anna , De Ponti Anna , Germani Massimiliano , Guanci Marco , Paolucci Mauro , Polucci Paolo , Russo Micaela , Sola Francesco , Valsasina Barbara , Visco Carlo , Zuccotto Fabio , Donati Daniele , Felder Eduard , Pesenti Enrico , Galvani Arturo , Mantegani Sergio , Isacchi Antonella
Published: April 2023

Supplementary Table S1 - PDF file 94K, Antiproliferative activity of NMS-E973
Table S7 from MicroRNA Array Analysis Finds Elevated Serum miR-1290 Accurately Distinguishes Patients with Low-Stage Pancreatic Cancer from Healthy and Disease Controls
Authors: Li Ang , Yu Jun , Kim Haeryoung , Wolfgang Christopher L. , Canto Marcia Irene , Hruban Ralph H. , Goggins Michael
Published: April 2023

Table S7 - XLSX file 13K, Supplemental Table S7. Univariate and multivariate analysis of serum miR-1290 and miR-486-3p and clinicopathologic factors associated with survival in pancreatic cancer
Supplementary Figure S3 from NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases
Authors: Fogliatto Gianpaolo , Gianellini Laura , Brasca Maria G. , Casale Elena , Ballinari Dario , Ciomei Marina , Degrassi Anna , De Ponti Anna , Germani Massimiliano , Guanci Marco , Paolucci Mauro , Polucci Paolo , Russo Micaela , Sola Francesco , Valsasina Barbara , Visco Carlo , Zuccotto Fabio , Donati Daniele , Felder Eduard , Pesenti Enrico , Galvani Arturo , Mantegani Sergio , Isacchi Antonella
Published: April 2023

Supplementary Figure S3 - PDF file 132K, Bioluminescence imaging of the intracranial growth of luciferized A375 cells after treatment with NMS-E973
Supplementary Figure 5 from Targeting the CD20 and CXCR4 Pathways in Non-Hodgkin Lymphoma with Rituximab and High-Affinity CXCR4 Antagonist BKT140
Authors: Beider Katia , Ribakovsky Elena , Abraham Michal , Wald Hanna , Weiss Lola , Rosenberg Evgenia , Galun Eithan , Avigdor Abraham , Eizenberg Orly , Peled Amnon , Nagler Arnon
Published: April 2023

Supplementary Figure 5 - PDF 65K,Apoptosis induction in BL-2 cells infiltrated to the BM