bluuebunny/crossref_metadata_2025 huggingface dataset:
Drugaddiction and its role in pedagogical processes, a hidden or an evident problem?
Authors: Munévar Quintero Fabio Ignacio , Quintero Corzo Josefina , Álvarez Márque Diana Yurany
Published: April 2023

Objective. To describe the way in which teachers who are being trained perceive and act towards drug-addiction in children, young people and teenagers.

Methodology. Narrative process supported in the comprehensive qualitative paradigm of case studies. Five journals from teachers who were being trained, men and women, who started their internship in official schools of the department of Caldas (Colombia) in groups with an average of 45 students, enrolled from 5th to 9th grade, were used as tools. Journals had stories, interpretations and thoughts about observed cases in the classes and scholar situations. Information was collected between 2006 and 2007.

Results. The dichotomy between the curriculum and the reality experienced by the students is evident. Trainees consider that the knowledge they receive is not enough to train them on how to intervene drug-addiction and health problems in the students, but they recognize these factors as determinants in the pedagogical processes and useful information to work in an interdisciplinary team with other professionals.

Conclusion. Even though theoretically the direct relationship between curriculum, culture and training processes is explained, they don’t have enough and opportune tools to solve physical, mental and emotional health problems, like drug-addiction that affect children, young people and teenagers integral training processes.
Comparison of the pain severity, drug leakage and ecchymosis rates caused by the application on tramadol intramuscular injection in Z-track and Air-lock techniques
Authors: Najafidolatabad Shahla , Janmohamad Malekzadeh , Mohebbinovbandegani Zinat
Published: April 2023

Objective. To compare the pain severity caused by the application of the Z-track and Air-lock intramuscular injections. 

Methodology. Unblinded clinical trial, where 90 female subjects aged between 18 and 60 years old were randomly assigned to two groups; the first group received the tramadol intramuscular injection using the Z-track technique (ZT) and the second group received it through the air- lock method (AL). A 10 centimeter linear visual scale was used to evaluate the injection pain. The scale length was considered as the pain severity. Data were analyzed using the SPSS version 13. Groups’ age, Body Mass index (BMI), and pain intensity were compared using unpaired student’s t test. 

Results. The study showed that the pain severity of patients in the AL method group was lower than in the ZT technique group (p< 0.05). There was no significant statistical difference between the age, the number of injections previously applied and the BMI between the groups. 

Conclusion. AL method produced less pain than the ZT technique; therefore it can be considered a better choice for intramuscular injections.
Non adherence factors to treatment of people with type 2 Diabetes Mellitus at home. Family caregiver’s view
Authors: Hoyos Duque Teresa Nury , Arteaga Henao María Victoria , Muñoz Cardona Mónica Johana
Published: April 2023

Objective. To understand the non adherence factors to treatment of people with type 2 Diabetes Mellitus (DM2) from the family caregiver’s view.

Methodology. Ethnographic study performed in 2008. 18 interviews to type 2 DM patient’s caregivers who be­longed to diabetes control programs from healthcare institutions of the city of Medellin (Colombia) were conducted. Six observa­tions of significant moments of care were also made.

Results. Treatment adherence in people with type 2 DM is mediated by multiple factors that difficult it, as: Cultural beliefs of the disea­se, disagreement between healthcare professionals and popular knowledge, tiredness of taking that many medicines, fear of multiple punctures for insulin application, dis­satisfaction with healthcare services and the long term cost of the disease.

Conclusion. From the family caregiver’s view, treatment adherence of people with type 2 DM is low as a consequence of multiple factors which influence it.
Tobacco consumption characteristics in nursing students of the University of Antioquia (Colombia)
Authors: Rodríguez Gázquez María de los Ángeles , Pineda Botero Sergio Alejandro , Vélez Yépes Luisa Fernanda
Published: April 2023

Objective. To describe the tobacco consumption characteristics in nursing students of the University of Antioquia.

Methodology. 435 nursing student’s descriptive study. A self applied form was used to report the information of the study variables.

Results. The life prevalence of cigarette consumption was 39.5%, (14.4% current and 25.1% former smokers), 15.4% of smokers are at high risk of nicotine addiction. One out of four smokers started the habit at university. During the last 12 months four out of five smokers have tried to quit smoking and three out of five have the intention to quit smoking. The smoking cessation rate was 63.8%. 98.2% of the students disagree with the fact that nurses smoke.

Conclusion. Cigarette consumption among nursing students although is not of great magnitude, it is a problem that require special attention from the agencies responsible for the university’s welfare programs.
Parenting practices among teenage mothers in the city of Duitama, Colombia.
Authors: González Bossa Alieth Rocío , Estupiñán Aponte María Rosa
Published: April 2023

Objective. To analyze parenting practices in teenage mothers of Duitama. Methodology. A qualitative assessment with comprehensive focus between February and October 2009 was conducted. It involved mothers aged between 13 and 19 years old chosen from the Municipality Education Secretariat databases, first sampled by logical criteria and then by a snowball. Emerging data from the in-depth interviews and participant observation which were subjected to a qualitative analysis, interpret feeding practices, hygiene, rest, discipline, values and support networks. Results. Executed by verbalization, penalties and prohibitions to instill respect and love values, teenage mothers represent the main figure of authority. They incorporate stimulating environments and games as a strategy for the formation of eating and rest habits. Due to permanent fears personal hygiene is initially delegated to the maternal grandmother as a knowledge provider source, emotional and affective support are considered essential to play the moternal role which also is strengthen by health entities, especially during the breast feeding period. Conclusion. Teenage mothers reproduce cultural patterns which are manifested in the intervention of the other caregivers, specially the teenager’s mother; they have a great impact on daily practices.
Theoretical conceptions on the theory on health education.
Authors: Diaz Valencia Paula Andrea
Published: April 2023

Objective. To identify the theoretical conceptions of health education (HE) reported by recent scientific literature. Methodology. Systematic review without meta-analysis of the scientific literature published on the theory on HE between 2000 and 2010 in Spanish, English, and Portuguese in PubMed, Elsevier, and SciELO. This included publications developing at least the theoretical categories on HE: conceptual development, history, current situation, as discipline, teaching and research. Results. Some 58 articles on HE were analyzed. The main categories contained in the articles were those of current situation and conceptual development. The definition and conceptualization of HE are diffuse. Most authors state that the term HE lacks identity and that tension exists between this concept and that of Healthcare Promotion. Conclusion. Processes in HE are not sufficiently qualified.
Surgical site infection incidence after a clean-contaminated surgery in Yasuj Shahid Beheshti hospital, Iran
Authors: Nobandegani Zinat Mohebbi , Doulatabad Shahla Najafi , Masoumeh Rambod , Ardeshir Afraseyabi
Published: April 2023

Objective. To determine the incidence rate of infection after a clean-contaminated surgery and its relationship with some risk factors.

Methodology. Cross sectional study, in a convenience sample of 300 patients who underwent surgery classified as clean-contaminated in a hospital of Yasuj, Iran. Samples were taken directly from the wound at the first dressing change to all the patients. They were studied to determine bacteria growth.

Results. The rate of infection after a clean-contaminated surgery was 53%. The most common gram positive microorganism was Staphylococcus aureus (22%), and among gram negative: Es­cherichia coli (26%), Klebsiella sp (26%) and Pseudomonas sp (25%). Significant correlation between the type of surgery and surgical site infection was found, it was not seen with the varia­bles sex and surgical procedure.

Conclusion. This study shows important problems regarding patient’s safety. Protocols should be reviewed to control infections.
Quality of life of caregivers of children with cardiopathy in Cartagena Colombia
Authors: Montalvo Prieto Amparo , Romero Massa Elizabeth , Flórez Torres Inna Elida
Published: April 2023

Objective. To describe the quality of life of relatives of children with complex congenital cardiopathies in Cartagena, Colombia. Methodology. Descriptive study conducted during the first half of 2008, it included 91 caregivers, users of the cardiology outpatient service from a children´s third level hospital selected through a convenience nonprobability sampling. The instrument proposed by Ferrell et al. was used to measure the quality of life of relatives taking care of the patient. It assesses the quality of life using 37 items that make up its meaning in welfare: physical (5 items), psychological (16 items), spiritual (9items) and social (7 items). The evaluation of each item is made using a 1 to 4 likert scale. The total score and subscale interpretation is an inverse relationship between the score and the deterioration of the caregiver status. Results. The caregiver group presented in the spiritual welfare subscale an average of 23.7 indicating the worst status, followed by the physical and social welfares with averages of 10.5 and 19.2 respectively. The psychological welfare was the best rated (average of 50.5). Conclusion. Caregivers perceive quality of life affected in a greater proportion in the spiritual welfare followed by social and physical welfare. Psychological welfare was the best evaluated. The caregiver experience significantly modifies the perception of quality of life of the people. Caregivers as an important source of informal care require health care system support, and as parts of it of the nursing professionals.
Quality of life of heroin dependent patients from a drug dependence attention center of Medellin (Colombia)
Authors: Tirado Otálvaro Andrés Felipe , Álvarez Gómez Matilde Ligia , Velásquez Tirado Juan david , Lugo Luz Helena , Giraldo Ferrer Luis Fernando , Suárez Bermudez Ana María , Wiedemann Julieth
Published: April 2023

Objective. To describe the quality of life in terms of health, in the different stages of treatment of patients addict to heroin attended in a drug-dependence attention center of Medellin.

Methodology. Cross sectional epidemiological study. 40 heroin addicts in the different stages of treatment: dishabituation, social reinsertion and maintenance program with methadone were interviewed in 2009. The SF-36 instrument for the evaluation of the quality of life and the Zung’s test for depression were used. Descriptive analysis and comparisons through non parametric tests to determine differences among the groups were performed (Group 1: Hospitalized patients, in phase of dishabituation and social reinsertion, and group 2: patients in any of the stages of the methadone’s maintenance program according to the treatment’s phase). Statistical significance was assumed if p<0.05 to determine differences among groups. 

Results. 40 patients participated (19 in group 1 and 21 in group 2). It was found that the quality of life was better in the patients in group 2 with statistical significant differences for all the domains, except for the physical function and mental health, which from the beginning had higher scores than the 75th percentile. 

Conclusion. Quality of life is better in patients who have longer time in the maintenance program with methadone.
Lifetime prevalence of drugs use in adolescents
Authors: Gómez Bustamante Edna , Cogollo Milanés Zuleima
Published: April 2023

Objective. To estimate the prevalence of lifetime use of psychoactive drugs in adolescents from Cartagena, Colombia. Methodology. Cross-sectional study carried out with a representative sample of 244 adolescents between 13 and 17 years of age from the general population. The study inquired on use of psychoactive drugs at any time of their lives (cocaine, ecstasy, inhalants, marihuana, or any drug that can be injected). The explanatory variables were adjusted through logistic regression. Results. Participants were from low and middle socio-economic levels. The lifetime prevalence of use of any drug was 20%. A total of 19% of the participants reported daily cigarette use and 18% had risky alcohol use. The following risk factors were related to drug use some time in their lives: daily cigarette use (OR=30.2; CI95%=11.8-77.6), not being religious (OR=5.8; CI95%=1.8- 18.8), male gender (OR=3.7; CI95%=1.1-13.1), and risky alcohol use (OR=3.5; CI95%=1.2-9.8). Conclusion. Use of any illegal drug some time in their lives by adolescents is high, constituting a healthcare problem, which should be addressed by government organizations. This use was related to male gender, not being religious, cigarette smoking, and having risky alcohol use.
Transvestites’ narratives about their experience with HIV/Aids
Authors: Lafaurie Villamil Maria Mercedes , Forero Rozo Ana Elizabeth , Miranda Jiménez Rafael José
Published: April 2023

Objective. To describe reflections of a group of transvestites, who work or have worked as prostitutes, about their experience as people who live with HIV/Aids, and their necessities of nursing support. Methodology. Qualitative study. 10 transvestites with HIV/Aids from 23 to 40 years of age, linked to prostitution, who attend a third level hospital of Bogota, were interviewed in depth. For data analysis the AtlasTi vr. 6 was used. Results. For these people money’s priority over health, alcohol consumption, and psychoactive substances take them not to use protection with the clients; preservative use failure with the sex couple precedes the infection. Depression is frequent. Attending the HIV program is essential for coping with the disease. Conclusion. There is a high HIV/Aids vulnerability in this group of people. It is necessary to create safe sex programs and strengthen life sense.
Nursing undergraduates experiences with nursing management subjects.
Authors: LLapa Rodriguez Eliana Ofelia , Sirqueira Carvalho Ticiana , Lisboa Gois Cristiane Franca , D’Ávila Nery Guimarães Alzira Maria
Published: April 2023

Objective. To explore the perception nursing students have towards their experiences with management subjects.

Methodology. Case study, in which, content analysis and the Strengths Opportunities Weaknesses and Threats matrix were used. The research was carried out from December 2009 to August 2010. 18 nursing students from the 6th and 7th semesters of the Federal Brasileña University participated

Results. From the nucleus identified the following categories emerged: 1) Nursing student and their reception in health institutions, 2) theory and practice connection, 3) professor’s role and subject organization, 4) student’s role in the subject. Possibilities and limitations about the analyzed teaching process emerged.

Conclusion. The subject’s teaching-learning process is not appropriate, reason why action strategies are required to balance academic contents with local contexts.
Arsenic Trioxide: Pharmacological Applications
Authors: Madrigal Redondo German , Rojas Salas María Fernanda , Vargas Zúñiga Rolando , González Corrales Daniela , Ortega Monge Celeste , Ceciliano Porras Pamela , Cerdas Delgado Mariana , Montero Rivera Jeison
Published: April 2023

Background: Arsenic trioxide is a chemical compound that has been used as a treatment for various diseases. Despite being potentially toxic, this compound has been used as a therapy to treat Acute Myeloid Leukemia and is being investigated as a possible treatment for different types of cancer. Objectives: The present review aims to describe the use and studies reported in the literature of Arsenic Trioxide as a possible therapeutic agent for Acute Myeloid Leukemia, Acute Promyelocytic Leukemia, Chronic Myeloid Leukemia, Multiple Myeloma, Myelodysplastic Syndrome, Hepatocellular Carcinoma, Lung Cancer, Neuroblastoma, Breast Cancer, Aplastic Hepatitis C, and HIV-1. Methods: A systematic review was conducted using databases (Elsevier, Google Scholar, PubMed) to compile documents published before December 2023. Results: Multiple pharmacological applications of arsenic trioxide have been reported to treat acute and chronic myeloid leukemia. Arsenic trioxide has been shown to inhibit angiogenesis, which helps treat multiple myeloma. Several studies have shown and suggested the effectiveness of arsenic trioxide as a treatment of hepatocellular carcinoma, lung cancer, neuroblastoma, prostate cancer, breast cancer, aplastic anemia, hepatitis C, and HIV-1.Conclusion: Despite potentially toxic effects, Arsenic compounds are therapeutic agents for multiple diseases, from syphilis to cancer. In recent years, more efficient ways have been investigated to deliver and find the specific dose to treat the disease, causing the fewest possible adverse effects.
Gastric cancer with tumour thrombosis of the portal vein: literature review and clinical case
Authors: Kharbediya E. Kh. , Peregorodiev I. N. , Magamedova S. S. , Nered S. N. , Stilidi I. S.
Published: April 2023

Tumoural portal vein thrombosis is a rare manifestation in gastric cancer. There is no reliable information in the worldwide literature on the overall survival of this category of patients. Few clinical cases have been described. This is a clinical case: a patient has diagnosed with body and antral gastric cancer complicated by tumour thrombosis of the portal vein and ingrowth into the pancreas. The clinical case described by the authors demonstrates yours the relevance of a number of issues. How can we namely be staging, treatment options and prognosis. The aim of this publication is to draw attention to a rare but common category of patient in oncologists’ clinical practice.
Análise de diagnósticos, intervenções e atividades de enfermagem em pacientes submetidos à hemodiálise secundária à COVID-19: estudo descritivo
Authors: Lima Lais Batista de , Pessoa Natalia Ramos Costa , Sousa Ramon Silva de , Amorim Rafaella Gomes Pinho , Palha Luana Carla de Andrade , Lima Joana Carvalho de Andrade , Gomes Anthony Moreira , Frazão Cecília Maria Farias Queiroz
Published: April 2023

Objetivo: Analisar os diagnósticos, as intervenções e atividades de enfermagem em pacientes submetidos à hemodiálise secundária à COVID-19. Método: Estudo descritivo, retrospectivo e de natureza quantitativa. A população do estudo foi representada pelos prontuários de pacientes submetidos à hemodiálise secundária à COVID-19, totalizando cerca de 64 registros. Consultaram-se os dados do instrumento de coleta de dados, bem como dados sociodemográficos, clínicos e indicadores dos diagnósticos de enfermagem. Para análise, utilizou-se da estatística descritiva e inferencial. Resultados: Os principais diagnósticos de enfermagem encontrados foram: risco de infecção, risco de volume de líquidos desequilibrado, déficit no autocuidado para banho/higiene íntima e troca de gases prejudicada. As intervenções e atividades assinaladas foram correspondentes aos diagnósticos traçados. Conclusão: O estudo possibilitou identificar os principais diagnósticos, as intervenções e atividades de enfermagem em pacientes acometidos pela COVID-19 que desenvolveram lesão renal aguda.
The Supreme Court of the RSFSR as a Court of First Instance
Authors: Vinnichenko O. Yu. , Gavrilova A. V.
Published: April 2023

The establishment of the Supreme Court of the RSFSR is connected with the unification of the judicial system, the renewal of the legal system and the first codification of republican legislation, due to the proclamation of a new economic policy and strict implementation of the principle of legality in all spheres of public life. In this regard, the Supreme Court of the RSFSR was entrusted with the most important function of ensuring the implementation of the principle of legality in the law enforcement activities of the republican courts. It was implemented through the consideration of cases by way of appeal in cassation and review of cases in a supervisory manner, through judicial explanations, interpretation of law, as well as a result of the reclamation of any cases that are in the proceedings of other courts of the Republic. The paper examines the little-studied practice of the Supreme Court of the RSFSR as a court of first instance. The material and procedural law of the Soviet period is analyzed to determine the categories of cases within the jurisdiction of the Supreme Court of the RSFSR in the first instance. The first procedural codes (Civil Procedure and Criminal Procedure of 1923) outlined the judicial activity of the Supreme Court of the RSFSR as the first instance in both civil and criminal cases. In this regard, it is stated both the generic jurisdiction of cases, due, in particular, to counter-revolutionary, economic or official crimes, and exceptional, determined by cases of national importance. In the future, during the period of updating legislation dictated by the new codification of law, only exclusive jurisdiction is noted in the activities of the Supreme Court of the RSFSR, predetermined by cases of special complexity or special social significance, including those related to encroachment on state and ideological interests. The political resonance that accompanied the consideration of such cases ensured the achievement of the preventive goal of the «show trial».
Source-Parameter Estimation after Attenuation Correction through the Use of Q Tomography
Authors: De Gori Pasquale , Pio Lucente Francesco , Chiarabba Claudio
Published: April 2023

The measurement of earthquake source parameters is affected by large uncertainties, and different approaches lead to large variability in results. One crucial aspect is the trade-off between attenuation (Q) and corner frequency (fc) in spectral fitting: The source corner frequency, inversely proportional to the fault size, can be severely masked by attenuation and site effects. In this article, we describe a method to solve the trade-off based on the fit of displacement spectra to find the source characteristics (corner frequency, fc, and the signal moment, Ω0) and the single-station attenuation operator (t*), in addition to the site response. We follow a parametric approach based on the use of 3D Q seismic tomography and a bootstrap-based method for selecting the best spectra fit. The correction of attenuation with synthetic values derived by 3D attenuation tomography efficiently deals with the trade-off between source and path terms, leading to small uncertainties in the determination of source unknowns (fc and signal moment, Ω0), thus yielding constrained estimates of source parameters for low- to medium-magnitude earthquakes. We show an application to the Emilia 2012 seismic sequence, for which we computed the source parameters for 1240 aftershocks (from an initial dataset of 1748) with local magnitude ranging from 2.0 to 4.7 using the spectral fit from P and S waves. About 80% of stress-drop estimations are characterized by relatively low uncertainties (within 20% of the estimated values), with maximum values of about 40% for the remaining 20%. The attenuation correction is effective to determine source parameters for small-magnitude earthquakes; hence, we obtain reliable estimates of source parameters for the entire aftershock sequence. This approach gives the opportunity to infer the mechanical state of a complete fault system by taking advantage of the larger number of low-magnitude events (with respect to the largest ones) that always follow a major earthquake.
Sobre la estructura de la jurisdicción contencioso-administrativa
Authors: Díez-Picazo Luis María
Published: April 2023

Este texto recoge una de las ponencias del seminario anual entre la Revista de Administración Pública y la Sala de lo Contencioso-Administrativo del Tribunal Supremo. Refleja la visión personal del autor sobre la estructura de la jurisdicción contencioso-administrativa en España, poniendo el acento en su evolución histórica. Trata, en especial, sobre la regulación de planta judicial y la competencia. Aborda, asimismo, el debate actual sobre la ampliación de la doble instancia y las posibles opciones.
Presupuestos y garantías de la expropiación forzosa en el Iusnaturalismo moderno
Authors: Rodríguez Portugués Manuel
Published: April 2023

Se estudia el tratamiento doctrinal de los presupuestos y garantías de la expropiación forzosa realizado por los juristas del derecho natural moderno. Se examina una gran cantidad de fuentes directas y se concluye que, frente a la nitidez con que fueron establecidas por uno de sus primeros representantes (Vázquez de Menchaca), dichos presupuestos y garantías no se configuraron con la firmeza que cabría esperar por parte de los iusnaturalistas posteriores. Más bien parece que la primera disciplina constitucional de la materia trató de reaccionar contra ciertas malas prácticas, en parte respaldadas por algunas de esas propuestas doctrinales.
La reciente evolución de la regla de prevalencia del derecho estatal en la doctrina constitucional
Authors: Ibáñez Buil Pedro
Published: April 2023

En el presente estudio se analiza la doctrina del Tribunal Constitucional sobre el significado y función de la regla de la prevalencia del Derecho estatal que establece el art. 149.3 de la Constitución. Algunas decisiones recientes del Tribunal Constitucional han ofrecido una interpretación algo distinta de la que venía siendo tradicional, permitiendo la inaplicación de las leyes autonómicas en determinados supuestos. El artículo pretende dar cuenta de la evolución de dicha doctrina del Tribunal y su situación en el momento actual.
Entre Roosevelt y Biden: ¿Aumentar el número de jueces del Tribunal Supremo y limitar su tiempo de servicio activo?
Authors: Pérez Alonso Jorge
Published: April 2023

Una vez se incorporaron al Tribunal Supremo los tres jueces que Trump propuso, por primera vez en décadas hay una sólida mayoría conservadora en el tribunal, que los liberales perciben como una potencial amenaza para algunos precedentes en asuntos como el aborto o el matrimonio entre personas del mismo sexo. Se han alzado voces defendiendo aumentar el número de jueces e introducir límites en su mandato. El presidente Biden expidió una orden ejecutiva creando una Comisión integrada por miembros de ambos partidos al objeto de analizar una reforma del Tribunal Supremo. La Comisión hizo público su informe final en diciembre de 2021. El presente trabajo trata los principales temas que abordó dicho informe. También analiza la frustrada iniciativa de Franklin Roosevelt para incrementar el número de jueces del Tribunal Supremo.
Chemotherapy resistance in non-small lung cancer regulate by holliday junction-recognizing protein through YAP1/NDRG1 transcriptional axis
Authors: Luo Chen
Published: April 2023

Lung cancer remains the leading cause of cancer death and often diagnosed at an advanced stage because of its speedy growth and early tendency to spread to other organs and tissues The objective of this study focuses on exploring the role of the HJURP/YAP1/NDRG1 transcriptional regulation axis in NSCLC. We observed significantly increased upregulation of HJURP expression levels in NSCLC tissues. Loss of function experiments identified that HJURP promotes NSCLC cells proliferation and decreases chemo-sensitivity. HJURP could affect the level of ubiquitination modification of YAP1 protein and then regulate its downstream transcriptional activity. Mechanistically, we found that YAP1 positively regulates NDRG1 transcription by binding the promoter region of the NDRG1 gene, and HJURP/YAP1/NDRG1 axis could affect chemotherapy sensitivity in NSCLC. Taken together, these findings provide insights into the HJURP as a tumor promoter in NSCLC via the activation of YAP1/NDRG1 axis, indicating HJURP may be a promising therapeutic target for NSCLC.
Congenital chylothorax managed with octreotide and skimmed milk: a case report
Authors: Sandhu Jaskirat Kaur , Kaur Satpreet
Published: April 2023

Pleural effusion occurs when a large amount of free fluid accumulates in the pleural space. A chylothorax is caused by chyle-containing lymphatic fluid draining into the pleural cavity. This is the most common type of pleural effusion observed during the neonatal period. It causes a number of respiratory and nutritional issues and has a significant mortality rate. It is usually treated by intercostal chest tube drainage and total parenteral nutrition. Octreotide is a relatively newer strategy in the management. Here we describe the case of a 16 days old male neonate who presented to us with sudden onset severe respiratory distress requiring invasive ventilation. Radiology suggested pleural effusion and so intercostal chest tube was inserted, which revealed Chylous effusion. The patient was successfully managed with dietary therapy including skimmed milk and octreotide infusion.
Recomendaciones para incorporar la gestión del riesgo de desastres y la adaptación al cambio climático en los proyectos de infraestructura: América Latina y El Caribe
Authors: Escuder-Bueno Ignacio , Yarritu-Sánchez Helena , Morales-Torres Adrián , Suarez Ginés
Published: April 2023

Esta nota técnica fue elaborada como parte del Diálogo Regional de Política “La Integración del Análisis del Riesgo de Desastres y Cambio Climático en la Inversión Pública”, celebrado en noviembre de 2020. En ésta se consideran los retos y oportunidades para que la metodología de análisis de riesgos de desastres y cambio climático del BID (DRCCA por sus siglas en inglés) sea adoptada por los países de la región.
Georreferenciamento: uma abordagem da Lei 10.267/2001 sobre registro de imóveis rurais utilizando tecnologia GPS
Authors: Nascimento Aline Bezerra do , Souza Karla Lira de
Published: April 2023

O Brasil possui um território com dimensões continentais, esta grande área dificulta o controle da ocupação de suas terras. Até pouco tempo, as técnicas utilizadas para realizar o cadastro de imóveis rurais no país se baseavam em aspectos basicamente descritivos, o que impossibilitavam relacionar o espaço geográfico cadastrado univocamente ao seu proprietário. [..]
Redes de distribuição de conteúdo: replicação de objetos reduzindo a sobrecarga nos backbones da internet
Authors: Gomes Anselmo Lacerda , Oliveira Felipe Soares de , Lima Giuseppe Anthony Nascimento de , Sousa Dênio Mariz Timóteo de
Published: April 2023

A Internet é o meio mais abrangente para requisição de objetos (dados) por parte dos usuários espalhados pelo mundo. Atualmente, a centralização do armazenamento de conteúdos muito acessados tem razoável impacto no tráfego gerado na Internet, principalmente nos casos em que os usuários finais estão distantes topologicamente do centro. Em geral, quanto maior à distância, maior é o número de sub-redes através das quais os dados devem ser transmitidos, o que gera atrasos, perdas e, eventualmente, congestionamentos. Uma Rede de Distribuição de Conteúdo (RDC) é um sistema de computadores conectados pela Internet e instalados em múltiplas redes de trânsito (backbones) que cooperam entre si de forma transparente para armazenar, replicar e fornecer dados para usuários finais. As RDCs são geralmente mantidas por provedores de serviços e seus componentes replicam bases de dados regionais usando algoritmos especiais de roteamento, permitindo a disponibilização racional do conteúdo de acordo com a localização geográfica e topológica do usuário final e das condições de tráfego da rede. Este trabalho é o resultado de uma pesquisa bibliográfica e documental que busca caracterizar e classificar, quanto a sua arquitetura, as principais RDCs atualmente em funcionamento na Internet.
Condutividade hidráulica não saturada de um fragipânico coeso determinada pelo método do perfil instantâneo
Authors: Guerra Hugo Orlando Carvallo , Lacerda Rogério Dantas de , Junior Genival Barros
Published: April 2023

A condutividade hidráulica é o coeficiente de proporcionalidade da equação de Darcy e que, no solo, expressa a facilidade com que a água se transmite no perfil. A sua avaliação sob condições de não saturação é de fundamental importância na resolução de problemas práticos ligados ao uso e manejo da água, visto que, a maior parte dos processos que envolvem o movimento de água em condições de campo, ocorre quando o solo se encontra não saturado. A presença de camadas subsuperficiais no solo, fortemente adensadas, apresenta forte influência na condutividade hidráulica do solo e, consequentemente, na infiltração e condução de água no perfil. Visando identificar estas camadas, realizaram-se testes pelo método do perfil instantâneo em solos dos tabuleiros costeiros do distrito de irrigação de Platô de Neopolis-SE para determinar a condutividade hidráulica (K(θ)) em função da umidade do solo. Valores do potencial matricial e umidade volumétrica correspondentes foram obtidos a partir de tensiômetros instalados a seis diferentes profundidades. Os resultados comprovaram a adequação do método utilizado, com os valores obtidos de 12,0 cm.h-1 e de 2,0 cm.h-1 para o conteúdo de água do solo de 0,22 cm3.cm-3 para a primeira e segunda profundidade, respectivamente.
Degradação da bacia hidrográfica do Rio do Cabelo e os efeitos ao meio ambiente
Authors: Farias Maria Sallydelândia Sobral de , Lima Vera Lúcia Antunes de , Dantas Neto José , Leite Eugênio Parcelli Fernandes , Andrade Antonio Ricardo Sousa
Published: April 2023

O presente trabalho tem como objetivo fazer um levantamento das principais fontes de poluição pontuais e difusas dos recursos hídricos na bacia hidrográfica de um rio que contribuem para degradação na área. A metodologia utilizada constou de visitas de campo e registros através de fotografias. No levantamento das fontes de poluição na bacia hidrográfica do Rio do Cabelo foram observadas contribuições poluentes significativas de: esgotos domésticos e industriais, resíduos sólidos, exploração da mineração pela retirada de areia, exploração agropecuária, desmatamento, aterramento do mangue, ocupação irregular da praia e urbanização caracterizada por uma ocupação em que predominam os condomínios, diversos loteamentos e residências construídas irregularmente. De um modo geral, as ações nocivas ao meio ambiente, tais como a devastação das florestas com um alto índice de substituição dos ambientes naturais; cortes e desmontes em encostas para instalação de edificações e sistema viário; mutilações nas várzeas e leito do Rio do Cabelo pela extração de areia; que comprometimento a qualidade da água do rio, trazendo risco aos ecossistemas ainda presentes, mesmo em área legalmente protegida pelo Plano Diretor da cidade de João Pessoa.
Uma metodologia para o descarte de resíduos oxidantes gerados em laboratórios de análise de solos
Authors: Farias Robson Fernandes de , Silva Cleiciane M. da , Silva Anna Paula V. de Siqueira e , Souza Rita de Cássia P. de
Published: April 2023

Um método para o descarte de resíduos oxidantes gerados em laboratórios de análise de solos é apresentado. O Cr+6 é primeiramente reduzido a Cr+3 pela reação com bissulfito de sódio, sendo em seguida precipitado sob a forma de hidróxido, mediante reação com hidróxido de sódio.
PROTEIN PROFILING OF CANDIDATE STRAINS OF BACTERIAL COMPOSITION
Authors:   FSBEI HE Ulyanovsk SAU, Suldina E. V. , Bogdanov I. I. ,   FSBEI HE Ulyanovsk SAU, Feoktistova N. A. ,   FSBEI HE Ulyanovsk SAU, Bart N. G. ,   FSBEI HE Ulyanovsk SAU
Published: April 2023

Organic farming and the application of organic and biological fertilizers and protective equipment is not only a promising, but also a safe way to obtain food products. Various bacterial compositions are widely used to increase the microbial activity of the soil, which increases the availability of nutrients that plants can easily absorb. They increase soil fertility by fixing nitrogen and dissolve insoluble phosphates in the soil, resulting in the formation of chemicals that promote plant growth. The aim of this work was to determine the presence of phytase, nitrogenase and alkaline phosphatase enzymes in strains of candidate bacteria of bacterial composition by proteomic profiling in polyacrylamide gel. The molecular weights of phytase, nitrogenase and phosphotase of candidate strains were determined in the system http://molbiol.ru/ based on amino acid sequences. After that, proteins with the corresponding molecular weights were detected on the forogram. According to the results of proteomic analysis of Bacillus subtilis, proteins with molecular weights of 50.5, 16.5 and 74.9 kDa corresponding to the enzymes phytase, nitrogenase and phosphatase were identified in 10 strains. Proteins with molecular weights of 41.8, 16.7 and 24.8 kDa corresponding to the enzymes phytase, nitrogenase and phosphatase were detected in 6 strains of Bacillus megaterium. 4 strains of Pseudomonas stutzeri contained proteins with molecular weights of 69, 31.8 and 73.5 kDa corresponding to the required enzymes. As a result of the carried out experiments, candidates bacterial strains were identified for the development of a biocomposition to increase the coefficient of assimilation of mineral components of fertilizers.
DEVELOPMENT OF PRIMER SYSTEM AND PROBE FOR IDENTIFICATION OF STAPHYLOCOCCUS AUREUS BY PCR-RV
Authors:   FSBEI HE Ulyanovsk SAU, Suldina E. V. , Feoktistova N. A. ,   FSBEI HE Ulyanovsk SAU, Lomakin A. A. ,   FSBEI HE Ulyanovsk SAU, Vasilenko A. V. ,   FSBEI HE Ulyanovsk SAU
Published: April 2023

The article presents the results of the development and testing of original system of primers and a probe for the identification of bacteria of the Staphylococcus aureus species by polymerase chain reaction in «real time» mode. The extension of domestic poultry industry opens up opportunities for the incidence rate of zoonoses. Staphylococci are one of the leading pathogens of bacterial infections in birds, and Staphylococcus aureus causes a wide range of diseases in chickens, including septic arthritis, subcutaneous abscesses and gangrenous dermatitis. Therefore, the development of methods for the timely detection of pathogenic variants of Staphylococcus aureus is an important task of food safety. For the development of a molecular genetic identification system, a unique DNA region of Staphylococcus aureus K39 NODE_3_length_262400_cov_12.378: 113,355..114,623 bp encoding transcription regulator U32 family peptidase was selected. With the help of the BLAST-primer NCBI resource, the UGENA program and the Oligoevaluator resource, the selection and design of oligonucleotide primers and a fluorescent probe for PCR were carried out. Optimization of primer systems showed that the optimal concentration is 3 pM of each primer per reaction, and an increase in the concentration of primers does not affect the effectiveness of the reaction. It has been experimentally established that the optimal concentration of the fluorescent probe in the reaction is 0.4 pM. Protocols have been selected for PCR-RV both in the presence of intercalating dye SYBR Green and using a fluorescent probe.The species specificity of selected primer systems was confirmed experimentally on 9 strains of heterologous bacterial genera and amounted to 100%. The sensitivity of primer system and probe was 102 copies.
TO THE QUESTION OF THE “SUNNY” NATURE OF THE WORDVIEW OF HRYHORII SKOVORODA
Authors: Musiy Valentina
Published: April 2023

The article is devoted to revealing the meanings and place of the constant "light" in the works of Hryhorii Savych Skovoroda. The idea of ​​its structural role in the picture of the world created in Skovoroda’s works is substantiated. In article the thesis about the viability, "sunshine" character of the  worldview of such outstanding and original artist-philosopher as Skovoroda.. The object of analysis is the poems and philosophical treatise "Booklet called Silenus Alcibiadis” (1776). The author of the article bases on the ambiguity of the constant "light" and founds the following meanings: "day, daylight hours, greetings to all in nature, time of sunshine", “a sign of the circle of life that passes man ("golden age")”; "happiness that everyone dreams of". It is also the spiritual part of human because, Skovoroda identified the cognition of light with self-knowledge, which, in turn, was the guiding principle of his conception of man. After all, the image of the light and of the sun was a manifestation of the wisdom of God, a necessary component of the universe.
Basing on the presence of the idea of ​​light as a divine energ, which is spread throughout the earth, in the philosophical system of Hryhorii Skovoroda, the author of the article concludes that this poet and philosoph was close to the ideas of hesychasm. According to the concept of hesychasts, each person becomes God-like with the help of concentrating on his inner world, spiritual perfection. As a result of inner transforming such person becomes capable to influence the world and make it perfect according to the divine plan of the world order. The ideas of hesychasm influenced the Skovoroda’s concept of two worlds, which is developed in his treatise "Booklet called Silenus Alcibiadis”. In the article the ideas of treatise are correlated with mythological ideas about the opposition of the light to darkness, with mystical systems, with Greek philosophy, in particular Epicurus.
TWITTER SOCIAL NETWORK: MAIN DISCURSIVE FEATURES IN UKRAINIAN-SPEAKING AND ENGLISH-SPEAKING COMMUNICATIVE ENVIRONMENT
Authors: Shvelidze L. D.
Published: April 2023

The article is devoted to a comparative analysis of the speech behavior of Ukrainian and English speakers on the social network Twitter. The specifics of Twitter as a social network and the main speech genre – tweet are characterized. A comparison of the frequency of network activity of Ukrainian and English speakers on Twitter is presented. A comparison of the speech behavior of users on Twitter and Facebook. The structural, semantic and linguo-pragmatic parameters of tweets in the Ukrainian-language and English-language communicative environment are determined. English-language tweeting has been shown to be highly subjective and based on communicative strategies of argumentation and discrediting; Ukrainian-language tweeting tends to involve ritual genres and self-presentation strategies as a priority.
Proto-professionalism: Opportunities for student learning and service to homeless people
Authors:   University of Leicester, UK, Anderson Elizabeth , Kinnair Daniel ,   Leicester Medical School College of Life Sciences University of Leicester, Ford Jenny ,   Leicester Medical School College of Life Sciences University of Leicester, Bleazard Lucy ,   Leicester Medical School College of Life Sciences University of Leicester, Malcherczyk Steve ,   Leicester Medical School College of Life Sciences University of Leicester
Published: April 2023

The concepts of professionalism including ethical practice, reflection, self-awareness, respect, teamwork and social responsibility are present in the healthcare curriculum but rarely learned in combination. The concepts can be combined when students receive practical experiences on the challenges of delivering health and social care to populations experiencing poverty and disadvantage. We report on work with homeless people in our local communities designed to align social accountability responsibilities with healthcare curricula through a student volunteering project; initially established in a medical school. Using an ethical approach we developed this learning through a staff-student-community partnership. The outcome was learning consisting of theoretical teaching, practice learning and the potential to volunteer. We report on the development phases over several years (2013-2017). The pedagogical evaluation used a sequential mixed methods approach. One hundred and ninety-five student participants scored pre- and post-questionnaires. Of these 75% completed reflective assignments and many went on to volunteer. Twenty of those who volunteered participated in one-to-one interviews. Scored data were analysed statistically and reflective written materials were analysed using content analysis. The interview data were analysed using thematic analysis. The learning was positively experience and students reported changed attitudes and understandings of homelessness. Practice-placements and volunteering further enhanced these insights and student’s perceptions of readiness for clinical practice. This can be described as proto-professionalism. The student-staff-community partnership offers an ethical platform on which to build sustainable local outreach projects. The students gained a deeper appreciation of social injustice for homeless people.
Exploring how Undergraduate BSc (Hons) Nursing (Child) Students Learn About End of Life Care Through Simulation – A Descriptive Case Study.
Authors:   University of Brighton, UK, Ford Lisa
Published: April 2023

Research suggests that nursing students have many anxieties about dealing with death and dying and feel unprepared to care for these patients as newly registered nurses. Effective education has been found to be an important factor in preparing nursing students for end of life care. Simulation is a pedagogical strategy widely used within nursing education and can provide an opportunity for students to develop their end of life care skills in the absence of opportunities in the practice setting. The purpose of this study was to explore how BSc (Hons) Nursing (Child) students learn about end of life care through simulation. A new simulation pedagogy was designed and delivered to second year child nursing students, and case study methodology was used to explore student learning. Data was collected through a focus group discussion and individual interviews. The findings revealed that during simulation, students learned about end of life care through a combination of hands-on practice and reflection, collaborating with their peers and facilitators, and by engaging in the experience through the provision of a safe and authentic environment. Learning theory was applied to the findings in order to explain the simulation learning process. In conclusion, learning through simulation is socially constructed, occurring through experiential learning which promotes perspective transformation. Student engagement in the simulation learning process is influenced by effective and supportive facilitation.
Se garder de la tyrannie de la peste en France (XVIe-XVIIe siècles)
Authors: Koźluk Magdalena
Published: April 2023

Prolongeant les recherches actuelles sur les pandémies en Europe et en particulier dans la France des XVIe et XVIIe siècles, nous nous sommes proposés d’examiner dans le présent article les recommandations médicales qui visaient à protéger les patients des épidémies de peste. En nous appuyant sur les régimes de santé et sur les traités de pestes de l’époque, nous avons analysé les instructions proposées par les médecins, chirurgiens et apothicaires, pour mener une vie saine, vertueuse et préservée de la maladie. Dans la première partie, nous avons rappelé au lecteur contemporain les fondements et théories de l’ancienne médecine qui, sur la base d’un système complexe et cohérent, privilégiait le « juste milieu » et la sobriété. Dans la seconde partie, nous avons regroupé les diverses prescriptions prophylactiques relatives aux six choses non-naturelles en nous concentrant sur le manger et le boire, le mouvement et le repos, l’évacuation des humeurs superflues et la conduite des passions.