bluuebunny/crossref_metadata_2025 huggingface dataset:
An Investigatory Examination as an Excess Link in the Mechanism of Material Evidence Inclusion in Criminal Case Files
Authors:   Professor of the Department of Criminalistics of the East Siberian Institute of the Ministry of Internal Affairs of Russia, Candidate of Legal Sciences, Assistant Professor, Antonov Vladimir A. , Rossinsky Sergey B. ,   Professor of the Department of Criminal Procedure Law of the Kutafin Moscow State Law University (MSAL), Doctor of Law, Assistant Professor
Published: November 2020

Purpose. doctrinal and statutory analysis of the essence of an investigatory examination aimed at identification of theoretical, legislative and applied issues arising in the course of acknowledging objects or documents as material evidence in a criminal case and elaboration of ways and means of their elimination and solution. Methodology: dialectics, analysis, synthesis, historical and legal method, system research method. Conclusions. 1) The scientific doctrine and the criminal procedure laws based on it combine two various forms of cognition of criminal case circumstances: a) an examination as a non-verbal investigatory action aimed at visual and graphic perception of material fragments of objective reality and b) further research of such fragments accompanied by formal and logical thinking and ending with coming to specific conclusions. 2) Primarily, an investigator has to attempt not at an examination of an object or a document rather at its safekeeping within a criminal case, ensuring an opportunity of its further research in the original state, in particular, in a court hearing. 3) An examination as a standalone investigatory action is an excess link in the mechanism of acknowledging objects or documents as material evidence stipulated by Part 2 Article 81 of the Criminal Procedure Code of the Russian Federation except for the cases when it is impossible to ensure their safekeeping up to the termination of the criminal case proceedings. Scientific and practical significance. The conducted research may be useful for scientists, students, postgraduate students and junior scientific assistants, practitioners and everyone interested in the issues of the investigatory action carrying out.
Chemical Constituents of Rumex abyssinicus Roots and Evaluation of Its Antimicrobial Activities
Authors: SHİFA Muaz , ABDİSSA Dele , ASERE Tsegaye Girma
Published: November 2020

Medicinal plants are usually screened for phytochemicals that may lead to its further isolation, purification and characterization of active principles. The roots of Rumex abyssinicus is used traditionally in Ethiopia for treating different diseases such as hepatitis, hemorrhoids, gonorrhea, typhus and wound. Thus, this study was conducted to investigate the phytochemicals and in-vitro antimicrobial activity extracts of the roots of R. abyssinicus. The roots were collected, chopped and air dried under shade in the Laboratory. Then, the dried plant material was subjected to sequentional extraction using maceration technique by soaking 1 kg of the sample in petroleum ether, chloroform, acetone and methanol and concentrated under reduced pressure using rotary evaporator. The crude extracts were dried and exposed to antimicrobial activity test using four bacterial and two fungal strains. Based on its antimicrobial activity, the acetone crude extract was used for column chromatographic isolation. Herein, two anthraquinones were isolated and characterized: chrysophanol and emodin. Its microbial activity was evaluated for potential antimicrobial activity against medically important strains by the agar disc diffusion method. The concentration of the crude extracts and isolated compounds was 100 mg/mL tested against S. aureus ATCC25903, K. pneumoniae NCTC13368, E. coli ATCC 25722, P. aeruginosa DSMZ 1117 and C. albicans and S.cerevisiae. The zone of growth inhibition of extracts and isolated compounds were compared with standard drugs like Gentamycin and Mancozeb. The results showed that isolated compounds (1 and 2) have demonestrated higher bacterial growth inhibition than the crude extracts. However, compound 2 was not actıve againist the S. cerevisiae strain.
La génesis ibérica del moderno poder naval
Authors: Vila González Manuel
Published: November 2020

At the end of the 15th century, a revolutionary approach to the use of the sea for its own benefit emerged from the two Atlantic Iberian peoples, characterized by having to face the challenge of ocean navigation and the exploration of new lands, something never even conceived previously. As happened in the previous historical stages with other protagonists, the main motivation to jump into the sea was economic. However, the geographic scale of the endeavor on this occasion ushered in a new era, characterized both by accelerated scientific development and by a globalization of commerce, politics, technology and culture (language, education and Christianity). Portugal conquered the oceans with the aim of establishing a network of commercial enclaves, creating the mold of what has since been considered the logical procedure for maritime powers in order to move freely through the seas that link the colonies with the metropolis. Accordingly, what for just over a century has been called sea (naval) power was nothing but the part of maritime power that was responsible for protecting its own trade from the ambition of others. Spain, however, undertook a similar epic with a more territorial (and patrimonial) mentality, due to which the oceans themselves came to be considered an integral part of the crown possessions as a link that united the different parts of the kingdom. That assumption created a new concept of naval power, by which in time of peace it complemented maritime power, which became at the same time a tributary of the former in the event of war. What the classic Anglo-Saxon writers (Alfred T. Mahan and Julian S. Corbett, in particular) described as maritime and sea power when studying the new history in British documentary sources is nothing more than the transposition of the principles that governed the constitution of Renaissance Portugal in a thalassocracy of planetary scope. The Spanish case is much more complex, since it was not only equally ignored in late-nineteenth-century and later historical-strategic studies (not only Anglo-Saxon, which is even more inexplicable), but it remains in the mist of the unexplored by not having had recognized historical continuity, which has contributed to preventing an adequate understanding of the historical dimension of the success (due to its resilience, durability, prosperity…) of the “empire” of the Hispanic Monarchy.
The Diamond of Influence: A Model For Exploring Behaviour in Research to Policy Linkages
Authors: Clark Louise
Published: November 2020

This learning paper presents an initial analysis of the emerging research to policy linkages within the Agricultural Policy Research in Africa (APRA) programme of the Future Agricultures Consortium, which is funded by the Foreign, Commonwealth & Development Office (FCDO). APRA has an innovative monitoring, evaluation and learning approach known as the ‘Accompanied Learning on Relevance and Effectiveness’ (ALRE), which is being delivered by a small team of embedded evaluation specialists. This paper discusses how ALRE has applied the COM-B (Capability, Opportunity, Motivation and Behaviour) (Mayne 2018; Mayne 2016; Michie, van Stralen and West 2011) model of behaviour change to explore the interactions and influencing strategies between researchers and policymakers in the context of agricultural policy research in Africa. These insights have produced the Diamond of Influence, a new ALRE-adapted model, which applies each of the COM-B elements to discuss the different aspects of research to policy processes, drawing on examples of how researchers in each of the APRA focus countries (Ethiopia, Ghana, Malawi, Nigeria, Tanzania and Zimbabwe) are engaging in policy spaces.
Computadores e ensino médio no nordeste: considerações de um problema de pesquisa
Authors: Melo Maria Emília Ferraz Almeida de , Soares Félix Alexandre Antunes , Omena Cristhiane Maria Bazílio
Published: November 2020

Este trabalho apresenta um levantamento bibliográfico de publicações científicas indexadas e teses/dissertações publicadas, relativas aos anos de 2013 e 2017, que referenciam as políticas de inserção das TIC nas escolas brasileiras, com ênfase em estudos desenvolvidos na região nordeste, apontando as principais barreiras encontradas nesse processo, assim como informações complementares sobre a visão dos docentes e discentes do ensino médio. Observou-se que políticas que aumentam a oferta destes recursos no ensino devem ser combinadas com mudanças no uso dessas ferramentas, principalmente com o treinamento específico de professores e da equipe gestora, além de maior conhecimento e planejamento do projeto pedagógico da escola, maior valorização da profissão docente e melhoria das políticas públicas que invistam na infraestrutura das escolas.
A integração de saberes sobre a Lua no Estágio Supervisionado/Licenciatura em Educação do Campo
Authors: Resende Edilene Pereira , Klepka Verônica , Crepalde Rodrigo dos Santos , Pinto Tânia Halley Oliveira
Published: November 2020

O texto discute sobre os resultados de uma experiência de integração de saberes no ensino de ciências, realizada durante o Estágio Supervisionado na Licenciatura em Educação do Campo de uma universidade federal. O projeto teve como objetivo proporcionar, por meio dos conhecimentos tradicionais de uma comunidade do campo do município de Sacramento, na região do Triângulo Mineiro, o reconhecimento acerca do emprego da orientação pelas fases da Lua em práticas sociais, especialmente aquelas ligadas ao plantio e à colheita. A proposta foi desenvolvida com uma turma do 9º ano do ensino fundamental, com auxílio de uma maquete que possibilitava a visualização das fases da Lua atrelada às informações dos conhecimentos tradicionais daquela comunidade do campo acerca da Lua nas plantações. Este trabalho assume como perspectiva teórica a educação intercultural e defende a necessária integração dos conhecimentos tradicionais dos povos do campo no ensino de ciências. A análise dessa experiência demonstra que, mesmo para estudantes do contexto do campo, onde ainda há estreito vínculo entre os conhecimentos tradicionais sobre a Lua e as práticas sociais de plantio e colheita, o conhecimento científicoainda é priorizado por esses estudantes, que atribuem seu valor ao relato escrito em livros, ao passo que o conhecimento tradicional carrega, muitas vezes, apenas a transmissão oral. Os resultados apontam ainda a potencialidade da integração de saberes das próprias comunidades do campo na sala de aula, de modo a reconhecer que, ao dar voz ao conhecimento construído pelos sujeitos do campo, está se rompendo comuma maneira secular de exclusão de sujeitos, identidades, saberes e existências.
Strategi Pengurangan Tingkat Pengangguran dengan Mengetahui Korelasi Tingkat Pertumbuhan Ekonomi dan Tingkat Angkatan Kerja di Kabupaten Bondowoso
Authors: Aprilia Sonia Nuri , Wulandari Ratri , Qomarodin Nizar
Published: November 2020

Pertumbuhan ekonomi sering dijadikan acuan sebagai indicator keberhasilan ekonomi di suatu wilayah. Indikator tersebut salah satunya adalah terkait pengangguran. Pengangguran merupakan suatu permasalahan serius yan harus ditindaklajuti oleh pemerintah Kabupaten Bondowoso untuk mencapai kesejahteraan masyarakat dan keberhasilan ekonomi daerah. Tujuan penelitian ini adalah untuk mengetahui pengaruh pertumbuhan ekonomi dan tingkat angkatan kerja terhadap tingkat pengangguran dan merumuskan strategi pengurangan tingkat pengangguran di Kabupaten Bondowoso. Dalam penelitian ini dilakukan dengan menggunakan analisis korelasi untuk megetahui hubungan antar variable yaitu variable pertumbuhan ekonomi dan tingkat angkatan kerja. Dilanjutkan dengan analytical hierarchy process (AHP) untuk mengetahui variabel yang menjadi prioritas dalam penelitian ini.  Hasil penelitian ini menunjakkan bahwa: Hasil analisis korelasi berdasarkan nilai Sig. (2-tailed) dan correlation pearson diketahui bahwa antara variabel pertumbuhan ekonomi dan angkatan kerja dengan jumlah pengangguran tidak berhubungan. Namun, karena r hitung atau pearson correlations dalam analisis ini bernilai positif maka itu artinya hubungan antara kedua variabel tersebut bersifat positif (+) atau dengan kata lain semakin meningkatnya pertumbuhan ekonomi dan angkatan kerja maka akan meningkatkan pula jumlah pengangguran. 2) Berdasarkan hasil Analitycal Hierarchy Process (AHP) untuk mengetahui faktor prioritas yang berpengaruh signifikan terhadap jumalah pengangguran, diketahui bahwa faktor prioritas yang berpengaruh signifikan terhadap jumlah pengangguran adan kualitas sumber daya manusia. 3) Berdasarkan faktor prioritas yang berpengaruh signifikan terhadap jumlah pengangguran, maka dapat dilauka upaya dalam mengurangi jumlah pengangguran di Kabupaten Bondowoso antara lain mengadakan pelatihan kerja, pengembangan dan bimbingan usaha secara mandiri, meningkatkan mutu pendidikan, dan meningkatkan hubungan antara lembaga pendidikan dan industri.
Daur Ulang Air Limbah Domestik untuk Peningkatan Kualitas Permukiman Kumuh dengan Penggunaan Reaktor Biofilter Anaerob Aerob dan Pengolahan Lanjutan
Authors: Nugraha Cahyadi Setya , Wijaya Nugroho Chandra , Romadona Wulida Putri , Akhsani Hendi Rengga , Arrochimi Dewi Rizqi
Published: November 2020

RT 002, RW 003 Kelurahan Bataran, Kecamatan Patrang termasuk kawasan permukiman kumuh sesuai dengan SK Bupati Jember Nomor 188.45/ 338/1.12/ 2016 Tentang penetapan lokasi Lingkungan Perumahan dan Permukiman Kumuh Perkotaan di Kabupaten Jember. Salah satu upaya dalam penanganan permukiman kumuh di Kota Jember adalah dengan adanya Rencana Pencegahan dan Peningkatan Kualitas Permukiman Kumuh Perkotaan atau RP2KP-KP. Terdapat tiga rencana pembangunan yang diterapkan di RT 002, RW 003 Kelurahan Baratan yaitu perbaikan kondisi rumah, pembangunan TPS dan pembangunan MCK. Program pembangunan MCK yang telah dilaksanakan di RT 002 RW 003 Kelurahan Baratan pada kondisi eksistingnya tidak dapat digunakan oleh masyarakat ketika musim kemarau karena tidak adanya pasokan air. Pengguaan reaktor biofilter anaerob aerob dan pengolahan lanjutan dapat memenuhi kebutuhan air dalam program pembangunan MCK di Kelurahan Baratan. Metode dalam perencanaan ini dilakukan secara kuantitaitf dan kualitatif. Metode kuantitatif dilakukan dengan menghitung kebutuhan air serta buangan limbah yang dihasilkan, sedangkan kualitatif dilakukan dengan studi literature terkait reaktor biofilter anaerob aerob dan pengolahan lanjutan serta dilanjutkan pada tahap implementasi desain serta strategi penerapanya. Reaktor anaerob aerob dan pengolahan lanjutan secara umum merupakan teknik daur ulang limbah domestik untuk dirubah menjadi air bersih sehingga dapat dimanfaatkan kembali. Hasil dari adanya pembahsan ini adalah berupa strategi progam yang ditangani oleh Dinas Perumahan Rakyat, Kawasan Permukiman dan Cipta Karya dan organisasi masyarakat setempat. Dengan adanya reaktor biofilter anaerob aerob dan pengolahan lanjutan pasokan air untuk keperluan MCK akan tetap terpenuhi sehingga program pembangunan MCK di RT 002 RW 003 dapat bermanfaat bagi masyarakat sehingga penganganan permukiman kumuh di Kota Jember dapat semakin berkualitas.
Los permisos retribuidos tras un periodo de turbulencias judiciales
Authors: Martínez Yáñez Nora María
Published: November 2020

La primera mitad del año 2020 ha sido especialmente prolífica en pronuncia­mientos del Tribunal Supremo en torno a los permisos retribuidos. Incluso el Tribunal de Justicia de la Unión Europea ha tenido ocasión de pronunciarse sobre una cuestión prejudicial planteada por la Audiencia Nacional en relación con esta institución. La mayor parte de estas resoluciones traen causa de un debate abierto entre la Audiencia Nacional y el Tribunal Supremo en torno a la forma de cómputo de los permisos retribuidos. La contundencia y reitera­ción del criterio del Tribunal Supremo en varias sentencias dictadas en marzo justifica la necesidad de analizar las líneas jurisprudenciales que han emergido del debate, destacando además otros avances jurisprudenciales en materia de retribución de los permisos.
Hylocereus polyrhizus Peel Extract Increase Testosteron Levels of Balb/C Mice (Mus musculus) Exposed Lead Acetate
Authors: I’tishom Reny , Wulandari Evy , Agus Sudjarwo Sri
Published: November 2020

Lead is a heavy metal, the main polluting material in the environment, which comes from gasoline, batteries, paint, pipes, soil, cosmetics, household appliances, and decorations. Lead is a free radical causing oxidative stress. Lead can accumulate in the body due to its slow elimination process. Lead increases oxidative stress by forming reactive oxygen species (ROS) such as superoxide ion (O2-), hydroxil radical (OH-), and nitric oxide (NO), and direct suppression of antioxidant reserves such as Superoxide Dismutase (SOD), Catalase, and Glutathione Peroxide (GPx). Hylocereus polyrhizus peel is a natural antioxidant that can overcome the toxic effects of lead. The aim of this study was to analyze the treatment of Hylocereus polyrhizus peel extract orally once in a day for 40 days to increase testosteron levels of Balb/C mice (Mus musculus) exposed to lead acetate. The type of this study was true experimental study with Post Test Only Control Group design. Forty mice aged 8-10 weeks and the range of the body weight 30-40 grams were divided into 5 groups (each group of 8 mice). K- group was the control group without lead acetate and Hylocereus polyrhizus peel extract. K+, P1, P2 and P3 group was given 100 mg/kgBW lead acetate orally on the 1st day until day 14th. P1, P2 and P3 group was continued by giving Hylocereus polyrhizus peel extract orally on the 15th day until 39th day. P1 with dose 250 mg/KgBW, P2 with dose 500 mg/KgBW, and P3 with dose 1000 mg/KgBW. The results showed significant differences in testosterone levels between the K+ groups with P1 and P2. The conclusion of this study is Hylocereus polyrhizus peel extract can increase the testosteron levels of mice exposed to acetate lead.
Computer Assisted Sperm Analysis: A Review
Authors: Agustinus  , Cennikon Pakpahan
Published: November 2020

Background: A semen analysis exam is a routine check that is done to evaluate fertility. The World Health Organization (WHO) recommended a manual method to obtain objective and standardized values. However, sometimes some errors can be found with this method such as motility. Computer-Assisted Sperm Analysis offers a way to reduce inaccuracies that often occur with manual methods.

Reviews:  CASA systems consist of a microscope which connected into a camera to detect microscopic sperm suspension images and a computer installed with special software to extract desired information and produce the desired output. In the morphological examination, CASA can reduce the coefficient of variation (CV) which is around 4.8% compared to the manual examination but the time required is longer than manual. CASA can visualize and evaluate sperm kinematics. Various parameters such as mean path velocity (VAP), curved velocity (VCL), straight-line velocity (VSL), lateral head displacement amplitude (ALH), or beat cross frequency can be obtained, and this allows a detailed view into the behavior of individual sperm. The limitations affecting CASA's ability to provide accurate results for sperm concentration and percentages of motile or progressively motile spermatozoa.

Summary: CASA has several advantages through its ability to calculate more detailed parameters, but a qualified operator must operate it because there is some potential for misinterpretation. The combination of The Manual and CASA is highly recommended for better results.
Parent Training Program for Autism Spectrum Disorder During The Covid-19 Pandemic Period in Indonesia
Authors: Ardiyani Ina Dewi , Febriyana Nining , Setiawati Yunias , Kalalo Royke Tony
Published: November 2020

Autism Spectrum Disorder (ASD) is a pervasive developmental disorder that shows difficulties in communication, social interaction, behavior, interests and activities that are limited and repetitive. The prevalence of ASD also continues to increase worldwide, followed by an increase in the need for early intervention in ASD children. The limited services available make early intervention a challenge in itself. The long Covid-19 pandemic has resulted in limited therapy, because therapy in treatment service facilities cannot be carried out as before. In this case it is important to involve parents as the primary caregivers for ASD children in interventions to anticipate the limited interventions due to a pandemic situation. Parent Training can be done as an effort to provide information, education, and skills to parents so that they can provide intensive, comprehensive, sustainable, and early intervention.
Development of New Analytical Method for Estimation of
Lansoprazole in Bulk and Tablet dosage forms
Authors: Karajgi S R , Mallikarjun D T , Somashekhar M , Shivakumar B
Published: November 2020

The present paper reports a simple, accurate and precise spectroscopic technique for
estimation of Lansoprazole by first order derivative technique in tablet dosage form. The
spectroscopic method for estimation of Lansoprazole by first order derivative technique was
carried out using methyl alcohol as solvent. The absorbance maximum was 275nm. Beers law
observed in the range of 30 - 150μg/ml concentration. The recovery studies demonstrated the
accuracy of the proposed procedure and the results were established as per ICH guidelines. The
technique was used successfully for the estimation of Lansoprazole in bulk and tablet and pure
dosage form.
Formulation and Evaluation of Roflumilast Fast dissolving
Tablets employing Lepidium sativum mucilage using 23
Factorial design
Authors: Bharathi A. , Sree K.Vijaya , Sekhar Naik D.Chandra
Published: November 2020

To evaluate fast dissolving tablets for Roflumilast employing with novel
superdisintegrant using lepidium sativum mucilage by using 23 factorial design.The physical,
chemical and micromeritic studies were evaluated for the prepared mucilage. To estabish fast
dissolving tablets of Roflumilast with lepidium sativum mucilage ie a superdisinitegrant in
different ratios by using direct compression method employing 23 factorial design. All the fast
dissolving tablets were evaluated pre compression and post compression parameters like
dissolution efficiency (DE%) percent of drug dissolved at 5 min (PD5). The Lepidium sativum
mucilage was to be found fine,free flowing crystaline powder and excellent swelling nature in
water. The FTIR and DSC studies were indicated to no interactions between roflumilast and
Lepidium sativum mucilage. All the formulation batches shows good quality with regrad to
drug content (98±0.092 to 100±0.026)hardness(3.4±0.43 to 3.6±0.64)friability (0.21±0.04 to
0.88±0.42). The optimized formulation batch shows less disintegrant time (52±0.24). The In–
Vitro wetting time was less (i.e., 90s) in optimized formulation F2. The water absorption ratio
of the formulated tablets was found to be in the range of (90.3±0.027 ). The cumulative drug
dissolved in the optimized formulation F2 was found to be ( 99%) in 5 min. Lepidium sativum
mucilage was found to be a super disintegrant which enhanced the dissolution efficiency when
combined with Crospovidone, croscarmellose sodium, and hence it could be used in the
formulation of fast dissolving tablets to provide immediate release of the contained drug within
5 min.
Phytochemical Evaluation and Antibacterial Activity of Fruit
Extract of Solanum surattense Burm F. against Some
Pathogenic Bacteria
Authors: Dhanalakshmi R , JaffarIqbal J , Jabeen K Nausath , Hidhaya M Noorul Zaithun , Meena K , Tamizharasan
Published: November 2020

The objective of this study was to evaluate phytochemical constituents and
antibacterial activity of hydroalcoholic extract of Solanum surattense fruit against some grampositive
and gram-negative bacterial strains. The evaluation of antibacterial activity was carried
out by using the disc diffusion method, determination of minimum inhibitory concentration
(MIC) and minimum bactericidal concentration (MBC). Ciprofloxacin was used as positive
control. Hydroalcoholic extract of Solanum surattense fruit containing alkaloids, flavonoids,
phenol, saponins, terpenoids, glycosides, sterols, proteins and tannins. Efficacy data analysis
showed that hydroalcoholic extracts of fruit of Solanum surattense (1 mg/ml) inhibited the
growth of Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Salmonella typhi with
mean diameters of inhibition zones being 24, 25, 28 and 30 mm respectively. On the other hand,
minimum inhibitory concentration and minimum bactericidal concentration value of 0.062 and
0.25 mg/ml, 0.062 and 0.25 mg/ml, 0.312 and 0.125 mg/ml, 0.156 and 0.0312 mg/ml were
recorded against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Salmonella typhi
respectively. Hydroalcoholic extracts of Solanum surattense fruit have potent antibacterial
activity against the different tested bacterial strains. This activity supports their use in treatment
of infections caused by such resistant bacteria.
Isolation, Characterization & Phytochemical Screening,
Analytical Method Development and Validation for the
Determination of Catechins in B.ciliata by RP HPLC Method
Authors: Saradhi NDVR , Gopal N Madan , Chetty C Madhusudhna , Sushmitha K
Published: November 2020

Ayurveda, an ancient system of medicines detailing a number of medicinal plants
and their activities in human or animals. The present research work was aimed to develop an
analytical procedure for the determination of catechins in the selected plant - B.Ciliata. It is
famously known as stone flower/ stone breaker having various biological activities like anti
urolithiatic, antiviral, antidiabetic antitumor and cardio protective activity. The methanolic
extract of the plant is isolated and a method is developed by using RP HPLC for the
determination of catechins in the crude plant extract using a C18 column (200*4.6mm, 5μ) and
detected at 241 nm. The method is validated for its system suitability, Linearity, Accuracy,
Precision, Robustness and sensitivity as per the ICH guidelines Q2(R1) to meet the analytical
procedure in academic and industrial usage
Insights on traditional and modern oil extractions of wheat
germ: Chemical and antimicrobial evaluation
Authors: Soltan Maha M. , Mahfouz Sabry A. , Karam Eman A. , Motawe Fatima H
Published: November 2020

Medicinal plants particularly with higher nutritional values are attracting the
attention of both the pharmacological and nutritional affairs. In the present study, we
extracted the wheat germ oil with cold press, hexane as well as supercritical carbon dioxide
(SC-CO2). All were chemically and biologically (antimicrobial) evaluated to investigate how
far can the differential in fatty acid composition affect the biological properties. The most
eminent result was recorded by SC-CO2 oil. It was the only among the extracted oils that
possessed moderate antibacterial and strong antifungal activities.
Short term Functional outcome of Harris HIP Score from
Open Reduction Internal Fixation action
(ORIF Intertrochanter)
Authors: Meliala Charles , Kadar Pranajaya Dharma , Akbar Husnul Fuad
Published: November 2020

Background- Intertrochanter fracture is commonly found in geriatric and young
active patient and it can affects the overall health system. The death rate of intertrochanter
fracture has increased by 1 person in 1 year with mortality rate of around 14-36%.Objective-
To find out the functional evaluation by Harris hip score from the action of open reduction
internal fixation (ORIF) on the intertrochanter femur fractures. Material and Methods-A total
of 42subjects were used in the study. The study wasanobservationalanalytic study with no
retrospective pairing and with a crossectional approach, whichaimedtoanalyzetheclinical
outcomeoftheHarris HipScore after performed ORIF intertrochanter femurfracture. In thiscase,
the control group are healthy femur from the same patient. Unpaired T-Test is use if normal
distributed data aquired, otherwise Mann-Whitney is the option. The affordable
populationofthe study waspatientswho were operated using internal fixation due to
intertrochanter femur fracture measures in January 2012 - June 2018.Results-In this case the
distribution of the number of intertrochanter femur fracture samples was 42 subjects with 14
women (33.3%) and 28 men (66.7%). The youngest age of the study subjects was 17 years and
the oldest age of the research subjects was 82 years with a mean and standard deviation of
60.77 ± 18.23 years, there were significant differences in outcomes of the clinical score of the
hip score of the action Open reduction internal fixation (ORIF ) in the case of intertrochanter
fracture femur, with a significance value of 0.0001 (<0.05).Conclusion-From the results of the
statistical analysis of the outcome of the clinical hip score score of ORIF compared to the
healthy side in the case of intertrochanter femur fractures, there is a significant result (15.1%)
between ORIF actions compared to the healthy side in the case of intertrochanter fracture
femur, with p value <0,0001.
Development and Validation of UV-Spectrophotometric and
HPLC Method determination of Dofetilide in Formulation
Authors: Dhurve Harsha , Parshuramkar Yasmini , Umekar Milind , Gupta Krishna
Published: November 2020

A new, simple, specific and economic UV Spectrophotometric method and HPLC
method for the estimation of Dofetilide content in bulk and laboratory prepared mixture. UV
spectrophotometric detection was carried out at absorption maxima (λmax) at 231nm using
methanol as a solvent. The quantitation of drug was carried out using A1% 1cm at 231nm and
Beer’s law was obeyed in the concentration range of 2.5-20 μg/ml, with correlation coefficient
value less than 1.The chromatographic separation was carried on a C-18 (250 mm × 4.6 mm,
5μ) column using an isocratic mode with a mixture of Acetonitrile:Phosphate Buffer (pH-7) in
the ratio of 55:45% v/v as a mobile phase. The flow rate was 1.5ml/min, temperature is
maintained at ambient and detection was made at 231 nm using Photodiode array (PDA)
detector. The developed method was validated according to ICH guidelines and different
analytical parameters such as linearity, precision, accuracy, specificity, limit of detection, limit
of quantitation were determined. The percent amount of drug estimated was nearly 100%,
found to be a good agreement with label claim of prepared laboratory mixture. The proposed
method was validated for its accuracy, precision, robustness, ruggedness, linearity, limit of
detection, limit of quantitation and was found to be in range (% RSD<2.0 and SD <±2.0). Both
methods were validated and found to be simple, sensitive, accurate, and precise. The results of
the study and statistical data proved the applicability of the present method in routine analysis
of Dofetilide in bulk as well as laboratory prepared mixture.
Evaluation of Histamine Levels in Smoked Fish Product in
South Sulawesi
Authors: Amir Nursinah , Syahrul  , Syamsuar
Published: November 2020

Histamine is a derivative composition of the histidine amino acid that is widely
found in scombroid fish such as skipjack, tuna and mackerel tuna. Skipjack and tuna are
fisheries commodities that are often used as raw material for smoked fish in several districts in
South Sulawesi. This study aims to evaluate the level of histamine in smoked fish products in
South Sulawesi. Smoked fish samples were immediately taken from processors in Bulukumba,
Bone and Sinjai districts using the Purpossive Sampling method. Analysis of histamine levels
was carried out at the Laboratory of the Application Center for Fisheries Product Quality
South Sulawesi used spectrophotometry based on SNI 2354.10: 2009. The results determined
the value of histamine levels of smoked fish products in South Sulawesi as required by SNI
2725: 2013 which was 3.00-7.32 mg / kg.
Comparative Analysis of Flexural Strength and Modulus Elasticity of Sustainable Concrete Using Supplementary Cementitious Material (SCM)
Authors: Samad Shahab , Shah Attaullah
Published: November 2020

The use of Supplementary Cementitious Material (SCM) is widely used in production of sustainable concrete. Blended cements, incorporating SCM such as Pulverized Fly Ash (PFA) and Ground Granulated Blast Furnace Slag (GGBFS) have been widely used to reduce the cement contents and avoid adverse environmental impacts of CO2 produced during cement manufacturing. The analysis of various structural properties of concrete such as compressive strength, flexural strength and modulus of elasticity is important for its structural application. In this research, flexural strength of 100mmx100mmx500mm beams made from blended cement were tested under three curing conditions i.e. winter, summer and under water and the flexural strength was calculated using EN-12390-5 at the ages of 28 days and 56 days. For modulus of elasticity, concrete cylinders 150mmx300mm were tested as per procedure described in BS 1881-121(1983) at the age of 28 days. The compressive strength, flexural strength and modulus of elasticity for blended cement incorporating PFA and GGBFS has been increased under summer curing environment. The experimental values of Modulus of Elasticity are compared with the provision of BS 1881.
INTRODUCING WAQF TO FRACTIONAL AND FULL RESERVE BANKING SYSTEMS FOR ECONOMIC STABILITY
Authors: Tekdogan Omer Faruk
Published: November 2020

Fractional reserve banking is a system in which banks extend loans by creating credit/deposit money, and which can be considered the basis of modern financial architecture. Nevertheless, it has been criticised because of its inherently weak and fragile structure in terms of financial and economic stability. As a theoretical solution, full reserve banking has been supported in academic circles, with many technical variations. However, Islamic economics can help to maintain financial and economic stability with its original institution of waqf. Besides performing social functions, waqf also undertakes financial intermediary functions and preserved financial stability in the period of the Ottoman Empire. The purpose of this study is to examine the effects of fractional reserve banking on economic stability and to make a comparison with full reserve banking to observe its potential as an alternative solution. The study also examines the efficiency of the Islamic social and economic institution of waqf in maintaining economic stability in both fractional and full reserve systems. The results demonstrate that full reserve banking is a promising approach to maintaining economic stability and that waqf enhances economic stability in both banking systems.
EFEITO DO Hg2+ E DOS ÍONS Cu2+, Fe2+, Ni2+, Sn2+ E Zn2+ NA ESTABILIDADE DE NANOPARTÍCULAS DE PRATA: UMA PRÁTICA INTERDISCIPLINAR DE NANOTECNOLOGIA EXPERIMENTAL
Authors: Katanosaka Aline , Fostier Anne , Santos Elias
Published: November 2020

EFFECT OF Hg2+ AND OF THE IONS Cu2+, Fe2+, Ni2+, Sn2+, AND Zn2+ ON THE STABILITY OF SILVER NANOPARTICLES: AN INTERDISCIPLINARY PRACTICE OF EXPERIMENTAL NANOTECHNOLOGY. The growing predominance of nanoscience and nanotechnology makes it increasingly important that these topics become an integral part of all scientific education. For this reason, in the present work, an interdisciplinary experiment of nanotechnology is introduced. As silver nanoparticles (AgNPs) are the most applied nanomaterial in consumer products, the current understanding of their stability is needed. Silver nanoparticles were synthesized using chitosan as a capping agent and a size distribution of 9.7 nm was determined by transmission electron microscopy. After preparation, the AgNPs colloid was divided into two parts. One part was stored in dark at 4.0 ± 1.0 o C and it was removed out from the fridge only to be analyzed by UV-vis. The second part was used to study the colloid stability in the presence of Hg2+, and also in the combination of mercury with the ions Cu2+, Fe2+, Ni2+, Sn2+, and Zn2+. The UV-vis analysis indicated that the AgNPs were oxidized in the presence of these ions, but in different intensities, which can be explained by using the electrochemistry approach. This work may be relevant for graduate-level or upper-level undergraduate experimental course preparation as the procedure is simple and easily reproducible in a typical chemistry laboratory.
Numerical simulation of polygonal spiral curved pipe with abrasive flow machining based on large eddy simulation
Authors: Zhao Weihong , Dong Xiwei , Hui Ximing , Peng Qifei , Li Junye , Zhang Chenri
Published: November 2020

Abrasive flow machining (AFM) technology can achieve precision machining finish for processing special curved pipe parts. In order to study the processing effect of abrasive flow machining for special curved pipe parts, polygonal spiral curved pipe is taken as the research object. The large eddy simulation (LES) method is used to simulate and numerically analyze the processing of polygonal spiral curved pipe. The static pressure cloud diagram, turbulence kinetic energy cloud diagram and turbulence intensity cloud diagram under different inlet pressures are obtained to analyze the influence of inlet pressure on the workpiece processed by abrasive flow. The fluid trace diagrams are obtained at the inlet and outlet of the workpiece, and the vortex changes of the fluid inside the workpiece are analyzed. The mechanism of vortex variation is revealed, which provides theoretical support for practical processing in the future.
Comparison of friction power loss between crankpin and crankshaft bearings on improving the engine power
Authors: Van Liem Nguyen , Guo Xiaoyan , Jiao Renqiang
Published: November 2020

To compare the friction power loss between the crankpin bearing (CPB) and crankshaft bearing (CSB) on improving the engine power, a slider-crank-mechanism dynamic model is established to compute the dynamic loads, Wp and Ws, impacting on the CPB and CSB. Based on the impact of Wp and Ws, a hydrodynamic lubrication model of the CPB and CSB is built to calculate the friction forces, Fp,s, and coefficient of frictions, μp,s, generated on the CPB and CSB. The simulation results of the Fp,s and μp,s on improving the engine power are then compared and analyzed, respectively. Under the same operation condition, the research results show that the friction power loss of the CPB is larger than that of the CSB under both the low and high engine speeds. Besides, the friction power loss of the CPB at 6000 rpm is also higher than that of 2000 rpm of the engine speed. Consequently, the friction power loss of the engine is greatly influenced by the crankpin bearing and at a high engine speed of 6000 rpm.
Vibration diagnosis of turbomachinery coupled with induction motor
Authors: G Krishnareddy , B Venkatesham , G Ramireddy
Published: November 2020

This paper is focusing on diagnosis for longitudinal and radial vibrations of turbomachinery coupled with induction motors. In this context, extensive field vibration measurements are conducted and analysed to identify the source of predominant vibrations on rotor bearing system in a chosen centrifugal compressor in the radial and longitudinal directions. As a first step, the measured overall vibration levels at multiple locations on bearing surface are compared with the existing ISO standard limits. These measurements showed severe longitudinal vibration values and failure of thrust collar assembly which were not considered in turbomachinery (API) design standards. The second step in diagnosis for vibration spectrum measurements are conducted both in longitudinal and radial directions during transient and steady state operations to find the vibration source and thrust collar assembly failure mechanism. This study on vibration diagnosis and analysis on turbomachinery is useful in correcting the severe longitudinal vibrations and damage control measures and corrections associated with static eccentric airgaps through motor air gap diagram.
Processing method of EMD endpoint effect based on SVRM extension
Authors: Chai Kai , Feng Shao-Wei
Published: November 2020

Aiming at the problem of endpoint effect in empirical mode decomposition (EMD), the application method of support vector regression machine (SVRM) in EMD extension data prediction is studied. Firstly, the basic principle, data extension method and parameter setting of SVRM are introduced. Secondly, several application methods of SVRM in EMD extension are studied to analyze and verify the operational efficiency and decomposition accuracy characteristics of each method respectively. Finally, the proposed extension method based on SVRM extreme value point prediction can greatly improve the operation efficiency of SVRM long time extension. The simulation signal analysis shows that the SVRM extreme point prediction extension method not only improves the accuracy and reliability of EMD decomposition, but also effectively inhibits the end-point effect phenomenon, significantly reduces the SVRM extension time, and improves the practicability of EMD method.
A system design method based on digital AGC photoelectric preamplifier gain adaptive control
Authors: Gu Xuefeng , Gu Gaoquan , Zhang Jing
Published: November 2020

In the process of measuring the radiated noise of underwater structure, using optical fiber hydrophone array is the main means of information acquisition. Due to the complexity of the measurement environment, when the wavelength of the light source and the array deformation in the optical fiber measurement system are changed, the power fluctuation of the input light and the demodulation failure of the system will be caused, which will affect the measurement effect of the radiated noise. For this reason, an adaptive control system for the optical source and the demodulator is designed, which can ensure the stability of the laser source and the digital demodulation system. The experimental data show that the adaptive control system designed in this paper can realize signal stable modulation and signal synchronous processing, which provides a more suitable scheme for accurate measurement of underwater equipment radiated noise.
Simulation of three-phase short circuit electromagnetic transient process of synchronous generator
Authors: Wang Hongtao
Published: November 2020

This paper studies the transient process of synchronous generator after three-phase short circuit, deduces the expression of stator current in the transient process of synchronous generator, and verifies the theoretical conclusion through simulation. After the short circuit occurs, the electromagnetic transient process is complex. In the electromagnetic transient process, the stator current and rotor current of synchronous generator appear attenuation oscillation due to direct-axis reactance, cross-axis reactance, transient reactance and sub-transient reactance. Based on the basic principle of synchronous generator, this paper analyzes the analytical expressions of stator straight axis current, stator cross axis current and total current. After that, the simulation model is built in Matlab/Simulink, and the simulation results are consistent with the theoretical analysis results. This simulation method provides convenience for analyzing the transient process of synchronous generator and has good engineering application value.
System dynamics simulation of crop yield under different irrigation water quality and quantity
Authors: Nozari Hamed , Azadi Saeed
Published: November 2020

Agricultural products are one of the major sources of food for people in many countries. So, increasing crop yield is a major challenge for governments as increasing the population. On the other hand, agricultural improvement needs to take into consideration the type of land and water available. The decrease of water availability and soil salinity are two major limiting factors in sustainable agriculture in the arid and semiarid regions. In this study, the combined effect of salinity and water stress on crop yield was simulated by developing a computer model based on a system dynamics approach. Model calibration and validation were performed using data collected from the Abshar Irrigation Network located on the hydrological Zayandehrud River. For each individual run of the model, two statistics were calculated: Root Mean Square Error and Standard Error. The averages of these indices were estimated as 2,777 kg·ha−1 and 0.07 for sugar beet yield, 0.026 and 0.09 for soil moisture and finally 0.54 dS·m−1 and 0.08 for salinity of the root zone, respectively. The result showed a good agreement between the simulation model and the actual data. Therefore, the model can be calibrated and used to estimate the crop yield with reasonable accuracy.
Suicide and Suicide Attempts in Elderly Patients: An Epidemiological Analysis of Risk Factors and Prevention
Authors: Makara-Studzińska Marta , Somasundaram Siva G. , Halicka Joanna , Madej Agata , Leszek Jerzy , Rehan Mohd , Ashraf Ghulam M. , Gavryushova Liliya V. , Nikolenko Vladimir N. , Mikhaleva Liudmila M. , Muresanu Cristian , Kirkland Cecil E. , Avila-Rodriguez Marco , Aliev Gjumrakch
Published: November 2020

:

A number of elderly patients commit suicide due to the interaction of various factors, including, for example, feelings of loneliness, financial distress, alcohol abuse, chronic pain, progressive diseases, and personality disorders. The data from the EU countries with the highest rates of suicide and suicide attempts among people over 55 years of age warrant the consideration of new approaches to address this social problem.

Methods:

PubMed and other databases, including Polish National data, were used for the analyses.

Results:

The average European suicide-attempt rate is 18 per 100 thousand inhabitants. More cases of suicides were reported among those over 55 years of age. Suicide attempts from the year 2012 to 2014 and deaths in 2012 have been reviewed. The risk factors involved in these events, such as depression and social situations including loneliness, health condition, etc., have been discussed to suggest a plausible preventative approach for this important elderly problem.

Conclusion:

The psychophysiology of elderly persons affected by retirement, socio-economic changes, limited personal autonomy, loneliness, lack of support by the family, and diseases ultimately may lead elderly patients to commit suicide. Thus, financial freedom, family support (respect, love, and care), proper medications, psychological and psychiatric interventions may help the elderly avoid suicidal thoughts and prevent attempts.
Recent Progress in the Drug Development for the Treatment of Alzheimer’s Disease Especially on Inhibition of Amyloid-peptide Aggregation
Authors: Liu Yuanyuan , Cong Lin , Han Chu , Li Bo , Dai Rongji
Published: November 2020

As the world's population is aging, Alzheimer’s disease (AD) has become a big concern
since AD has started affecting younger people and the population of AD patients is increasing
worldwide. It has been revealed that the neuropathological hallmarks of AD are typically characterized
by the presence of neurotoxic extracellular amyloid plaques in the brain, which are surrounded
by tangles of neuronal fibers. However, the causes of AD have not been completely understood yet.
Currently, there is no drug to effectively prevent AD or to completely reserve the symptoms in the
patients. This article reviews the pathological features associated with AD, the recent progress in
research on the drug development to treat AD, especially on the discovery of natural product derivatives
to inhibit Aβ peptide aggregation as well as the design and synthesis of Aβ peptide aggregation
inhibitors to treat AD.