bluuebunny/crossref_metadata_2025 huggingface dataset:
The need for earlier recognition of attention deficit hyperactivity disorder in primary care: a qualitative meta-synthesis of the experience of receiving a diagnosis of ADHD in adulthood
Authors: Long Nichole , Coats Heather
Published: April 2022

Background

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopment disorder that affects individuals across the lifespan. ADHD causes dysfunction when left untreated. Individuals receiving a diagnosis in adulthood have a unique life experience because of their delayed diagnosis.

Objectives

To identify and methodically review qualitative studies that explored the experiences of receiving a diagnosis of ADHD in adulthood, conduct an interpretive analysis of the identified studies, and produce a qualitative meta-synthesis to provide an understanding of these experiences.

Methods

Studies with adults diagnosed with ADHD in adulthood, focussed on experiences of receiving a delayed ADHD diagnosis, used qualitative methods, and were cited in PubMed, OVID, and ProQuest databases. Out of 251 studies identified, 7 met inclusion criteria.

Results

This qualitative meta-synthesis produced 2 main themes: ADHD as an identity and ADHD as a diagnosis, and 5 subthemes: identity before diagnosis, identity after diagnosis, the unnecessary struggle, the diagnosis as a revelation and a burden, and a functional life was finally possible.

Conclusion

Overall, this study showed that delayed diagnosis of ADHD causes suffering and dysfunction that could be mitigated through earlier diagnosis and treatment.
Interseismic deformation and strain-partitioning along the Main Köpetdag Fault, Turkmenistan, with Sentinel-1 InSAR time-series
Authors: Dodds N , Daout S , Walker R T , Begenjev G , Bezmenov Y , Mirzin R , Parsons B
Published: April 2022

The Main Köpetdag Fault (MKDF) is a predominantly right-lateral strike-slip fault that dissects the northern edge of the Köpetdag mountains of Turkmenistan and Iran. The fault represents the northernmost expression of deformation from the Arabia–Eurasia collision to the east of the Caspian Sea, and plays an important role facilitating the motion of the South Caspian Basin (SCB). Despite the kinematic significance of the MKDF, previous geodetic measurements of the slip-rate across the fault have been highly variable, with a recent geological slip-rate supporting evidence for rapid motion across the fault. To resolve this ambiguity, we derive Sentinel-1 InSAR time-series in both the ascending and descending LOS (line-of-sight) to measure interseismic motion across the MKDF. This implements a processing strategy for the correction and performance analysis of tropospheric models from GACOS (Generic Atmospheric Correction Online Service), which suggests a 25–40 per cent underestimation in the amplitude of the tropospheric path delay in this region. Modelling the rate of fault-parallel motion across the MKDF and combining this with a geological slip-rate constrains 9 ± 2 mm yr–1 right-lateral motion, along with a shallow locking depth of ≈6 km. The LOS time-series resolves path delays of greater than 1 mm yr–1 in both LOS geometries to the north of the MKDF, aligned with mapped frontal thrust scarps to the north of the MKDF. Modelling this as uplift from deformation across these frontal thrusts estimates 4 ± 2 mm yr–1 of shortening across the fault system. This implies that convergence measured with GNSS within the East Caspian Lowlands is partitioned across frontal thrusts to the north of the MKDF. Revising an Iran–Eurasia–SCB velocity triangle suggests that motion along the conjugate MKDF and Shahroud fault zones is representative of the motion of the SCB, which is moving at 10 ± 2 mm yr–1 in a direction of 330° ± 10° relative to Eurasia.
Resolving the location of small intracontinental earthquakes using Open Access seismic and geodetic data: lessons from the 2017 January 18mb 4.3, Ténéré, Niger, earthquake
Authors: Craig Timothy J , Gibbons Steven J
Published: April 2022

A low-magnitude earthquake was recorded on 2017 January 18, in the Ténéré desert in northern Niger. This intraplate region is exceptionally sparsely covered with seismic stations and the closest open seismic station, G.TAM in Algeria at a distance of approximately 600 km, was unusually and unfortunately not operational at the time of the event. Body-wave magnitude estimates range from mb 4.2 to mb 4.7 and both seismic location and magnitude constraints are dominated by stations at teleseismic distances. The seismic constraints are strengthened considerably by array stations of the International Monitoring System for verifying compliance with the Comprehensive Nuclear Test-Ban-Treaty. This event, with magnitude relevant to low-yield nuclear tests, provides a valuable validation of the detection and location procedure for small land-based seismic disturbances at significant distances. For seismologists not in the CTBT system, the event is problematic as data from many of the key stations are not openly available. We examine the uncertainty in published routinely determined epicentres by performing multiple Bayesloc location estimates with published arrival times considering both all published arrival times and those from open stations only. This location exercise confirms lateral uncertainties in seismologically derived location no smaller than 10 km. Coherence for interferometric synthetic aperture radar in this region is exceptionally high, and allows us to confidently detect a displacement of the order 6 mm in the time frame containing the earthquake, consistent with the seismic location estimates, and with a lateral length scale consistent with an earthquake of this size, allowing location constraint to within one rupture length (≤5 km)—significantly reducing the lateral uncertainty compared with relying on seismological data only. Combining Open Access-only seismological and geodetic data, we precisely constrain the source location, and conclude that this earthquake likely had a shallow source. We then discuss potential ways to continue the integration of geodetic data in the calibration of seismological earthquake location.
Monitoring creep along the Hayward Fault using structure-from-motion photogrammetry of offset curbs
Authors: Swiatlowski Jerlyn L , Funning Gareth J , Barth Nicolas C
Published: April 2022

We present observations of sidewalk curbs that are offset by creep on the Hayward Fault in Fremont, CA. Using structure-from-motion photogrammetry techniques, we construct 3-D models from suites of 2-D photos taken from 2015 to 2018 at 20 sites along the fault. By aligning and comparing these models, we measure the 3-D displacements of each offset sidewalk through time at precisions of ∼0.5 mm yr−1. We find that on average individual offset curbs record <40 per cent of the overall creep rate measured at nearby alignment arrays (which span a fault-perpendicular distance of 100 m or more). The ‘fault trace’ can more accurately be considered a zone of deformation, narrower than an alignment array width but wider than one curb length (∼3–5 m). Sites for which we have multiple time intervals to compare show interannual temporal variability in creep rate and direction. Our methods offer a new, complementary approach to cheaply and efficiently document creep-related deformation in an urban setting, one that may be particularly useful for tracking deformation of engineered materials and their cohesion to the subsurface. Given the use of readily available equipment (consumer-grade camera, GPS, ruler), ease of data collection and accessibility of urban field sites, we believe that this style of monitoring would lend itself particularly well to citizen science efforts.
The impact of caring for family members with mental illnesses on the caregiver: a scoping review
Authors: Phillips Rita , Durkin Mark , Engward Hilary , Cable Graham , Iancu Maria
Published: April 2022

A large number of multidisciplinary, qualitative and quantitative research suggests that providing care for family members with mental health illnesses can have both positive and negative effects on the carers’ wellbeing. However, to date a comprehensive overview and synthesis of literature that compares and contrasts positive and negative effects of family-caregiving on the carer is missing. To address this gap, this scoping review examines the effects of family-caregiving on carers’ wellbeing. A Boolean search generated a total of 92 relevant articles that were included in the analysis. The results suggest that, to understand the effects of family-caregiving on the carer’s mental and physical wellbeing, it is necessary to take a combination of situational and sociodemographic characteristics into consideration. Elderly, female, spousal-carers and primary-carers may be a group that is at risk of suffering from a lack of positive mental and physical wellbeing as a result of caring. However, the negative effects of caregiving can be balanced by extraversion, social support and religious or spiritual beliefs. Therefore, future interventions that aim to promote family caregivers’ wellbeing may need to take personality, particular circumstances as well as cultural and personal beliefs into consideration.
High site-fidelity and low mortality of juvenile Atlantic cod (Gadus morhua) in subarctic coastal habitat during their first winter
Authors: Geissinger Emilie A , Gregory Robert S , Laurel Benjamin J , Snelgrove Paul V R
Published: April 2022

In subarctic Newfoundland, age-0 juvenile Atlantic cod (Gadus morhua) settle into coastal habitats in several summer and fall pulses, yielding a broad length-frequency distribution prior to their first winter. The first winter is often associated with physiological and metabolic stress and has been considered a critical survival period determining cohort strength. We evaluated size-structured overwinter mortality and movement using mark–recapture and condition metrics by marking 226 cod in two batches one week apart, in October 2016. We estimated fall and overwinter mortality, and documented movement of fish recaptured in May 2017 using Cormack–Jolly–Seber models. We recaptured 30 marked juveniles. High fall mortality characterized late settling cohorts relative to earlier settling cohorts (16.6%∙d−1 vs. 4.5–7.7% ∙d−1). Overwinter mortality was unexpectedly low (0.0052 and 0.0022% ∙d−1). Individual condition (Fulton’s K) of juvenile cod remained high throughout winter across all size groups. We expected higher mortality of juvenile cod and broad dispersal of juveniles over winter (32 weeks). In contrast, our results indicated low mortality and high site-fidelity in their first winter. This study indicates the period leading up to winter is important for survival, suggesting winter is not a survival bottleneck and may even provide a refuge compared to the rest of the year.
Prey-switching to fishery discards does not compensate for poor natural foraging conditions in breeding albatross
Authors: Kuepfer Amanda , Votier Stephen C , Sherley Richard B , Ventura Francesco , Matias Rafael , Anderson Orea , Brickle Paul , Arkhipkin Alexander , Catry Paulo
Published: April 2022

Fishery discards supplement food for many seabirds, but the impacts of declining discards are poorly understood. Discards may be beneficial for some populations but have negative impacts by increasing bycatch risk or because they are junk-food. The Falkland Islands support > 70% of global black-browed albatross Thalassarche melanophris populations, which feed on discards. However, the effect of discards on population demographics, and implications of fishery management changes, are unknown. We analysed stomach contents of black-browed albatross chicks across eight breeding seasons (2004–2020) from New Island, Falkland Islands, to assess variation in discard consumption and how this relates to foraging conditions and breeding success. Across years, 68%–98% of samples contained natural prey, whilst 23%–88% of samples contained fishery discards. Discard consumption was positively related to fishery catches of hoki Macruronus magellanicus and sea surface temperature anomalies SSTA (°C), and negatively related to breeding success. These results suggest a diet-switching behaviour for Falkland Islands albatrosses, whereby birds switch from preferred natural prey to suboptimal discards when environmental conditions, and hence natural feeding opportunities, are unfavourable. Crucially, this study highlights that fishery discards do not compensate for poor natural foraging conditions for breeding albatrosses in the long term.
Support for the hypothesis that growth of eastern Baltic cod is affected by mild hypoxia. A comment on Svedäng et al. (2022)
Authors: Brander Keith
Published: April 2022

Stock biomass and size composition of eastern Baltic cod (EBC) has declined, with low recent stock productivity attributed to loss of major spawning areas, reduced growth rates, and possibly increased natural mortality. Svedäng et al. present valuable new data for evaluating the causes of these changes. However, contrary to their own conclusions, those new data actually provide both direct and indirect support for the hypothesis that the reduced growth rate observed may be due to a decline in ambient oxygen for small cod in the Bornholm Basin area (SD25). Their long time series of reproductive volume (RV) extends our knowledge of historic changes in the limits to spawning imposed by salinity and oxygen. However, the causes and consequences of such spawning area changes are well established. Therefore, this Comment only addresses the contentious debate about causes of decline in growth.
Taking feminism beyond the state: FIFA as a transnational battleground for feminist legal critique
Authors: Duval Antoine
Published: April 2022

The Fédération Internationale de Football Association (FIFA) plays a fundamental role in defining and asserting the boundary between men and women in football. Its decisions condition the way the game is played, the way players and clubs contract, and the way the FIFA World Cup is organized and experienced by people around the world. FIFA’s private transnational governance regime is, at least hypothetically, as prone to gender bias and discrimination as states or international organizations. Nevertheless, feminist legal scholars have rarely directed their sights on transnational private regulators such as FIFA. This article suggests to take the feminist legal critique beyond its traditional battlegrounds and highlights FIFA as a transnational governance site deserving feminist scrutiny. While it does not advocate for the introduction of specific policies, it aims to provide a convincing justification and a helpful roadmap for future feminist engagements with FIFA.
The basins of attraction of the global minimizers of non-convex inverse problems with low-dimensional models in infinite dimension
Authors: Traonmilin Yann , Aujol Jean-François , Leclaire Arthur
Published: April 2022

Non-convex methods for linear inverse problems with low-dimensional models have emerged as an alternative to convex techniques. We propose a theoretical framework where both finite dimensional and infinite dimensional linear inverse problems can be studied. We show how the size of the basins of attraction of the minimizers of such problems is linked with the number of available measurements. This framework recovers known results about low-rank matrix estimation and off-the-grid sparse spike estimation, and it provides new results for Gaussian mixture estimation from linear measurements.
Reliably Assessing Duration of Protection for Coronavirus Disease 2019 Vaccines
Authors: Lin Dan-Yu , Zeng Donglin , Gu Yu , Krause Philip R , Fleming Thomas R
Published: April 2022

Decision making about vaccination and boosting schedules for coronavirus disease 2019 (COVID-19) hinges on reliable methods for evaluating the longevity of vaccine protection. We show that modeling of protection as a piecewise linear function of time since vaccination for the log hazard ratio of the vaccine effect provides more reliable estimates of vaccine effectiveness at the end of an observation period and also detects plateaus in protective effectiveness more reliably than the standard method of estimating a constant vaccine effect over each time period. This approach will be useful for analyzing data pertaining to COVID-19 vaccines and other vaccines for which rapid and reliable understanding of vaccine effectiveness over time is desired.
Susceptibility profiles and resistance genomics of Pseudomonas aeruginosa isolates from European ICUs participating in the ASPIRE-ICU trial
Authors: Torrens Gabriel , van der Schalk Thomas Ewout , Cortes-Lara Sara , Timbermont Leen , del Barrio-Tofiño Ester , Xavier Basil Britto , Zamorano Laura , Lammens Christine , Ali Omar , Ruzin Alexey , Goossens Herman , Kumar-Singh Samir , Kluytmans Jan , Paling Fleur , MacLean R Craig , Köhler Thilo , López-Causapé Carla , Malhotra-Kumar Surbhi , Oliver Antonio ,   the ASPIRE-ICU study team
Published: April 2022

Objectives

To determine the susceptibility profiles and the resistome of Pseudomonas aeruginosa isolates from European ICUs during a prospective cohort study (ASPIRE-ICU).

Methods

723 isolates from respiratory samples or perianal swabs of 402 patients from 29 sites in 11 countries were studied. MICs of 12 antibiotics were determined by broth microdilution. Horizontally acquired β-lactamases were analysed through phenotypic and genetic assays. The first respiratory isolates from 105 patients providing such samples were analysed through WGS, including the analysis of the resistome and a previously defined genotypic resistance score. Spontaneous mutant frequencies and the genetic basis of hypermutation were assessed.

Results

All agents except colistin showed resistance rates above 20%, including ceftolozane/tazobactam and ceftazidime/avibactam. 24.9% of the isolates were XDR, with a wide intercountry variation (0%–62.5%). 13.2% of the isolates were classified as DTR (difficult-to-treat resistance). 21.4% of the isolates produced ESBLs (mostly PER-1) or carbapenemases (mostly NDM-1, VIM-1/2 and GES-5). WGS showed that these determinants were linked to high-risk clones (particularly ST235 and ST654). WGS revealed a wide repertoire of mutation-driven resistance mechanisms, with multiple lineage-specific mutations. The most frequently mutated genes were gyrA, parC, oprD, mexZ, nalD and parS, but only two of the isolates were hypermutable. Finally, a good accuracy of the genotypic score to predict susceptibility (91%–100%) and resistance (94%–100%) was documented.

Conclusions

An overall high prevalence of resistance is documented European ICUs, but with a wide intercountry variability determined by the dissemination of XDR high-risk clones, arguing for the need to reinforce infection control measures.
Stress-Delta B-Type Natriuretic Peptide Does Not Exclude ACS in the ED
Authors: Susman Stephen J , Bouffler Andrew , Gordee Alexander , Kuchibhatla Maragatha , Leahy J Clancy , Griffin S Michelle , Christenson Robert H , Newby L Kristin , Limkakeng Alexander T
Published: April 2022

Background

There are many detectable changes in circulating biomarkers in the setting of myocardial ischemia. We hypothesize that there are associated changes in circulating B-type natriuretic peptide (BNP) level after stress-induced myocardial ischemia, which can be used for emergency department (ED) acute coronary syndrome (ACS) risk stratification.

Methods

In a prospective study, we enrolled 340 patients over the age of 30 receiving an exercise echocardiography stress test in an ED observational unit for suspected ACS. We collected blood samples at baseline and at 2 and 4 h post–stress test, measuring the relative and absolute changes (stress-delta) in plasma BNP concentrations. In addition, patients were contacted at 90 days and at 1 year posttest for a follow-up. We calculated the diagnostic test characteristics of stress-delta BNP for a composite outcome of ischemic imaging on stress echocardiogram, nonelective percutaneous coronary intervention, coronary artery bypass graft surgery, subsequent acute myocardial infarction, or cardiac death at 1 year via a logistic regression. We analyzed the 2-h BNP concentrations using an ANOVA model to adjust for the baseline BNP level.

Results

Baseline and 2-h post-stress BNP were both higher in the positive outcome group, but the stress-delta BNP was not. Stress-delta BNP had a sensitivity and specificity, respectively, of 53% and 76% at 2 h and 67% and 68% at 4 h. It was noted that patients with the composite outcome had a higher baseline BNP level.

Conclusions

BNP stress-deltas are poor diagnostic means for ACS risk stratification, but resting BNP remains a promising prognostic tool for ED patients with suspected ACS.
International Legal Issues Arising from Repatriation of the Children of Islamic State
Authors: Bagheri Saeed , Bisset Alison
Published: April 2022

The detention of children of Islamic State within Kurdish-controlled camps in Syria presents a complex dilemma for national authorities and the international community. Although a small number of states have repatriated their nationals, overall, little progress has been made and thousands of children continue to languish in deplorable conditions. Resolution has been urged from both humanitarian and international security perspectives, but Western states, in particular, have sought to avoid responsibility, often using legal mechanisms to impede repatriation efforts. This article asks whether international legal frameworks can provide a route to resolution. It argues that by centralizing the international law and policy on children’s rights, repatriation becomes the priority rather than domestic political and security objectives. Conceptual light is shed on the ways in which international human rights law standards can be mobilized for the protection of conflict-affected children as individual rights holders.
Review of Protecting Human Rights Defenders at Risk, ed. Alice M. Nah
Authors: Fletcher Laurel E
Published: April 2022

This review considers Protecting Human Rights Defenders at Risk, edited by Alice M. Nah, and explores the book’s key implications for human rights practitioners and their organizations.
On semantically labelled syntax trees and the non-existence of certain Sahlqvist formulae
Authors: Iliev Petar
Published: April 2022

We elaborate on semantically labelled syntax trees that provide a method of proving the non-existence of modal formulae satisfying certain syntactic properties and defining a given class of frames and use them to show that there are classes of Kripke frames that are definable by both non-Sahlqvist and Sahlqvist formulae, but the latter requires more propositional variables.
Policies and Practices to Address Cancer’s Long-Term Adverse Consequences
Authors: Bradley Cathy J , Kitchen Sara , Bhatia Smita , Bynum Julie , Darien Gwen , Lichtenfeld J Leonard , Oyer Randall , Shulman Lawrence N , Sheldon Lisa Kennedy
Published: April 2022

As cancer detection and treatment improve, the number of long-term survivors will continue to grow, as will the need to improve their survivorship experience and health outcomes. We need to better understand cancer and its treatment’s short- and long-term adverse consequences and to prevent, detect, and treat these consequences effectively. Delivering care through a collaborative care model; standardizing information offered to and collected from patients; standardizing approaches to documenting, treating, and reducing adverse effects; and creating a data infrastructure to make population-based information widely available are all actions that can improve survivors’ outcomes. National policies that address gaps in insurance coverage, the cost and value of treatment and survivorship care, and worker benefits such as paid sick leave can also concurrently reduce cancer burden. The National Cancer Policy Forum and the Forum on Aging, Disability, and Independence at the National Academies of Sciences, Engineering, and Medicine sponsored a virtual workshop on “Addressing the Adverse Consequences of Cancer Treatment,” November 9-10, 2020, to examine long-term adverse consequences of cancer treatment and to identify practices and policies to reduce treatment’s negative impact on survivors. This commentary discusses high-priority issues raised during the workshop and offers a path forward.
Inhibition of human ether-à-go-go-related gene K+ currents expressed in HEK293 cells by three gingerol components from ginger
Authors: Liu Miaomaio , Yang Yakun , Zhang Muqing , Xue Yucong , Zheng Bin , Zhang Yuanyuan , Liu Yu , Chu Xi , Sun Zhenqing , Han Xue
Published: April 2022

Objectives

Gingerols are bioactive compounds derived from ginger, our experiment investigates the effects of 6-, 8- and 10-Gin on the human ether-à-go-go-related gene (hERG) K+ channels by using patch clamp technology.

Key findings

hERG K+ currents were suppressed by 6-, 8- and 10-Gin in a concentration-dependent manner. The IC50 values of 6-, 8- and 10-Gin were 41.5, 16.1 and 86.5 μM for the hERG K+ currents, respectively. The maximum inhibitory effects caused by 6-, 8- and 10-Gin were 44.3% ± 2.0%, 88.6% ± 1.3% and 63.1% ± 1.1%, respectively, and the effects were almost completely reversible.

Conclusion

These findings suggest that 8-Gin is the most potent hERG K+ channel inhibitor among gingerol components and may offer a new approach for understanding and treating cancer.
Mucin-poor mucinous tubular and spindle cell carcinoma of the kidney: one case report and review of the literature
Authors: Zhong Minglei , Zhang Zhaocun , Qi Wenqiang , Zhou Yongheng , Lv Guangda , Jiang Xianzhou
Published: April 2022

Mucinous tubule and spindle cell carcinoma (MTSCC) of the kidney is a rare renal pleomorphic tumor considered as low-grade malignant, with occurring mainly in female. Few mucin-poor MTSCC cases have been reported so far. A typical MTSCC is composed of closely arranged tubules with pale mucus matrix and spindle cell components. Mucin-poor MTSCC is difficult to distinguish from other renal cell carcinomas due to small amount of mucus. We reported a case of mucin-poor MTSCC in a 37-year-old male with detailed imaging, histology, immunohistochemical and next-generation sequencing information, looking forward to providing an insight into mucin-poor MTSCC.
The response of mesophyll conductance to ozone-induced oxidative stress is genotype-dependent in poplar
Authors: Joffe Ricardo , Berthe Audrey , Jolivet Yves , Gandin Anthony
Published: April 2022

The CO2 diffusion conductance within the leaf mesophyll (gm) is considered a major limiting factor of photosynthesis. However, the effects of the major secondary air pollutant ozone (O3) on gm have been poorly investigated. Eight genotypes of the economically important tree species Populus × canadensis Moench were exposed to 120 ppb O3 for 21 d. gm showed a genotype-dependent response to O3-induced oxidative stress and was a major limiting factor of net assimilation rate (Anet), ahead of stomatal conductance to CO2 (gsc) and of the maximum carboxylation capacity of the Rubisco enzyme (Vcmax) in half of the tested genotypes. Increased leaf dry mass per area (LMA) and decreased chlorophyll content were linked to the observed gm decrease, but this relationship did not entirely explain the different genotypic gm responses. Moreover, the oxidative stress defence metabolites ascorbate and glutathione were not related to O3 tolerance of gm. However, malondialdehyde probably mitigated the observed gm decrease in some genotypes due to its oxidative stress signalling function. The large variation of gm suggests different regulation mechanisms amongst poplar genotypes under oxidative stress.
Interpreting through AI: A note on the possibility of weaving ancient traditions with novel technologies
Authors: Neuman Yair , Danesi Marcel
Published: April 2022

Language, like any other semiotic code, is a sign system whose forms (words, phrases, sentences, etc.) are governed by the standing for principle (SFP). However, the SFP is more complex to envision when ‘composite forms’ such as novels and dialogues are involved. In this article, and following the work of Bakhtin and Gasset, we present the idea that a composite semiotic form, such as a paragraph in a novel, does not stand for a simple referential situation only, but provides us with a context for anticipation. We show how these ideas can be expressed in the state-of-the-art language models in AI (Artificial Intelligence) and the way AI may provide us with novel directions for developing old practices of interpretation.
Not Half True
Authors: Mankowitz Poppy
Published: April 2022

The word ‘true’ shows some evidence of gradability. For instance, there are cases where truth-bearers are described as ‘slightly true’, ‘completely true’ or ‘very true’. Expressions that accept these types of modifiers are analysed in terms of properties that can be possessed to a greater or lesser degree. If ‘true’ is genuinely gradable, then it would follow that there are degrees of truth. It might also follow that ‘true’ is context-sensitive, like other gradable expressions. Such conclusions are difficult to reconcile with most existing theories: deflationists and inflationists alike tend to reject the thesis that one true truth-bearer can have more or less truth than another. Based on work in natural language, I argue that ‘true’ is not a genuinely gradable expression. I also provide an explanation of the apparent evidence for gradability. Hence there is no reason to think that there is a truth property that comes in degrees.
The Struggle Over Education in the Yishuv: Rav Kook and the Herzliya Gymnasium
Authors: Cohen Yehudit , Goldstein Yossi
Published: April 2022

The following discussion seeks to clarify the attitude of Rav Kook, the chief rabbi of Jaffa and one of the most important moral figures in the Jewish community, regarding the founding and early development of the Herzliya Gymnasium in 1905, the world’s first secondary school to employ Hebrew as its language of instruction. The Gymnasium was criticized for two reasons: the way of life it promoted, which ran counter to the spirit of the Halacha (Jewish law), and its method of teaching Bible studies. Despite his opposition to the worldview of the founders and teachers of the Gymnasium, Kook refrained from speaking out against them publicly, preferring a less confrontational approach. He also wholeheartedly believed that they contained a degree of inner goodness that would cause them to return to what he regarded as the righteous path. Moreover, he was convinced that so long as he was unable to offer the public an alternative religious institution, one that would provide the same level of general studies as the Gymnasium, embarking on a public campaign against it was ill-advised. In his view, the situation also had a positive side: the existence of the Gymnasium provided an incentive for Jewish religious educational institutions to raise their own academic levels in order to compete. Had the Gymnasium not had something positive to offer, it would not have posed a threat at all.
Impact of COVID-19 on the antifungal susceptibility profiles of isolates collected in a global surveillance program that monitors invasive fungal infections
Authors: Pfaller Michael A , Carvalhaes Cecilia G , DeVries Sean , Rhomberg Paul R , Castanheira Mariana
Published: April 2022

Studies demonstrated the impact of the COVID-19 pandemic in the prevalence and susceptibility profiles of bacterial and fungal organisms. We analyzed 4821 invasive fungal isolates collected during 2018, 2019, and 2020 in 48 hospitals worldwide to evaluate the impact of this event in the occurrence and susceptibility rates of common fungal species. Isolates were tested using the CLSI broth microdilution method. While the percentage of total isolates that were C. glabrata (n = 710 isolates) or C. krusei (n = 112) slightly increased in 2020, the percentage for C. parapsilosis (n = 542), A. fumigatus (n = 416), and C. lusitaniae (n = 84) significantly decreased (P < .05). Fluconazole resistance in C. glabrata decreased from 5.8% in 2018–2019 to 2.0% in 2020, mainly due to fewer hospitals in the US having these isolates (5 vs. 1 hospital). Conversely, higher fluconazole-resistance rates were noted for C. parapsilosis (13.9 vs. 9.8%) and C. tropicalis (3.5 vs. 0.7%; P < .05) during 2020. Voriconazole resistance also increased for these species. Echinocandin resistance was unchanged among Candida spp. Voriconazole susceptibility rates in A. fumigatus were similar in these two periods (91.7% in 2018 and 2019 vs. 93.0% in 2020). Changes were also noticed in the organisms with smaller numbers of collected isolates. We observed variations in the occurrence of organisms submitted to a global surveillance and the susceptibility patterns for some organism-antifungal combinations. As the COVID-19 pandemic is still ongoing, the impact of this event must continue to be monitored to guide treatment of patients affected by bacterial and fungal infections.

Lay Summary

Secondary infections were documented in COVID-19 patients. We compared the prevalence of invasive fungal isolates consecutively collected in 48 worldwide hospitals and their susceptibility patterns between 2020, the year of the global COVID-19 pandemic, and the two prior years.
Asteroid phase curves using sparse Gaia DR2 data and differential dense light curves
Authors: Wilawer E , Oszkiewicz D , Kryszczyńska A , Marciniak A , Shevchenko V , Belskaya I , Kwiatkowski T , Kankiewicz P , Horbowicz J , Kudak V , Kulczak P , Perig V , Sobkowiak K
Published: April 2022

The amount of sparse asteroid photometry being gathered by both space- and ground-based surveys is growing exponentially. This large volume of data poses a computational challenge owing to both the large amount of information to be processed and the new methods needed to combine data from different sources (e.g. obtained by different techniques, in different bands, and having different random and systematic errors). The main goal of this work is to develop an algorithm capable of merging sparse and dense data sets, both relative and differential, in preparation for asteroid observations originating from, for example, Gaia, TESS, ATLAS, LSST, K2, VISTA, and many other sources. We present a novel method to obtain asteroid phase curves by combining sparse photometry and differential ground-based photometry. In the traditional approach, the latter cannot be used for phase curves. Merging those two data types allows for the extraction of phase-curve information for a growing number of objects. Our method is validated for 26 sample asteroids observed by the Gaia mission.
Long-term evolution of decayless kink oscillations of solar coronal loops
Authors: Zhong Sihui , Nakariakov Valery M , Kolotkov Dmitrii Y , Anfinogentov Sergey A
Published: April 2022

Long-term evolution of instantaneous parameters of decayless kink oscillations of six solar coronal loops observed for longer than 2 h each is studied. The oscillations are analysed by processing sequences of 171 Å images obtained with the Solar Dynamics Observatory (SDO)/Atmospheric Imaging Assembly (AIA) in the time interval from 2020 December till 2021 June, with the motion magnification technique. It is established that decayless kink oscillations could exist for more than 30 or 40 oscillation cycles. Neither the loop brightness nor instantaneous parameters of the oscillations show a monotonic increase or decrease during the oscillation. The observed instantaneous oscillation periods and amplitudes are found to vary randomly in time, with distributions around the mean values that resemble Gaussian profiles. Mean values of the oscillation periods and amplitudes are consistent with previous observations of this phenomenon. A power-law dependence of the oscillation period on the displacement amplitude is found, with the power-law index of 0.41 and with the 95 per cent confidence interval of [0.39, 0.71]. In general, we established the lack of correlation between instantaneous oscillation parameters and loop brightness. One exception is an event with relatively strong anticorrelation of the amplitude and the loop’s brightness, with the cross-correlation coefficient of about −0.81, but this effect requires a further study. Fourier power spectra of the envelopes of the time-evolving instantaneous amplitudes and periods are white noise, indicating that consecutive values of the instantaneous parameters are independent of each other. The results obtained provide an empirical ground for validating and comparing existing and future theoretical models of decayless kink oscillations of coronal loops.
Apostle–Auriga: effects of different subgrid models on the baryon cycle around Milky Way-mass galaxies
Authors: Kelly Ashley J , Jenkins Adrian , Deason Alis , Fattahi Azadeh , Grand Robert J J , Pakmor Rüdiger , Springel Volker , Frenk Carlos S
Published: April 2022

Modern hydrodynamical simulations reproduce many properties of the real Universe. These simulations model various physical processes, but many of these are included using ‘subgrid models’ due to resolution limits. Although different subgrid models have been successful in modelling the effects of supernovae (SNe) and active galactic nuclei (AGNs) feedback on galactic properties, it remains unclear if, and by how much, these differing implementations affect observable halo gas properties. In this work, we use ‘zoom-in’ cosmological initial conditions of two volumes selected to resemble the Local Group (LG) evolved with both the Auriga and Apostle galaxy formation models. While the subgrid physics models in both simulations reproduce realistic stellar components of L⋆ galaxies, they exhibit different gas properties. Namely, Auriga predicts that the Milky Way is almost baryonically closed, whereas Apostle suggests that only half of the expected baryons reside within the halo. Furthermore, Apostle predicts that this baryon deficiency extends to the LG (r ≤ 1 Mpc). Some of the baryon deficiency in Apostle is due to SNe feedback at high redshift, which generates halo-wide outflows, with high covering fractions and radial velocities, which both eject baryons and significantly impede cosmic gas accretion. Conversely, in Auriga, gas accretion into the halo appears to be almost unaffected by feedback. These differences appear to result from the different energy injection methods from feedback (both SNe and AGNs) to gas. Our results suggest that both quasar absorption lines and fast radio burst dispersion measures could constrain these two regimes with future observations.
The non-ideal finite Larmor radius effect in the solar atmosphere
Authors: Pandey B P , Wardle Mark
Published: April 2022

The dynamics of the partially ionized solar atmosphere is controlled by the frequent collisions and charge exchange between the predominant neutral hydrogen atoms and charged ions. At signal frequencies below or of the order of either of the collision or charge exchange frequencies, the magnetic stress is felt by both the charged and neutral particles simultaneously. The resulting neutral-mass loading of the ions leads to the rescaling of the effective ion-cyclotron frequency (it becomes the Hall frequency), and the resultant effective Larmor radius becomes of the order of few kms. Thus, the finite Larmor radius effect that manifests as the ion and neutral pressure stress tensors operates over macroscopic scales. Whereas parallel and perpendicular (with respect to the magnetic field) viscous momentum transport competes with the Ohm and Hall diffusion of the magnetic field in the photosphere–chromosphere, the gyroviscous effect becomes important only in the transition region between the chromosphere and corona, where it competes with the ambipolar diffusion. The wave propagation in the gyroviscous effect-dominated medium depends on the plasma β (a ratio of the thermal and magnetic energies). The abundance of free energy makes gyro waves unstable with the onset condition exactly opposite of the Hall instability. However, the maximum growth rate is identical to the Hall instability. For a flow gradient of ${\sim} 0.1 \, \mbox{s}^{-1}$, the instability growth time is 1 min. Thus, the transition region may become subject to this fast-growing gyroviscous instability.
ProFuse: physical multiband structural decomposition of galaxies and the mass–size–age plane
Authors: Robotham A S G , Bellstedt S , Driver S P
Published: April 2022

We present the new ProFuse r package, a simultaneous spectral (ultraviolet to far-infrared) and spatial structural decomposition tool that produces physical models of galaxies and their components. This combines the functionality of the recently released ProFound (for automatic source extraction), ProFit (for extended source profiling), and ProSpect (for stellar population modelling) software packages. The key novelty of ProFuse is that it generates images using a self-consistent model for the star formation and metallicity history of the bulge and disc separately, and uses target images across a range of wavelengths to define the model likelihood and optimize our physical galaxy reconstruction. The first part of the paper explores the ProFuse approach in detail, and compares results to published structural and stellar population properties. The latter part of the paper applies ProFuse to 6664 z < 0.06 GAMA galaxies. Using re-processed ugriZYJHKs imaging we extract structural and stellar population properties for bulges and discs in parallel. As well as producing true stellar mass based mass–size relationships, we further extend this correlation to explore the third dimensions of age and gas phase metallicity. The discs in particular demonstrate strong co-dependency between mass–size–age in a well-defined plane, where at a given disc stellar mass younger discs tend to be larger. These findings are in broad agreement with work at higher redshift, suggesting discs that formed earlier are physically smaller.
Merger-induced galaxy transformations in the artemis simulations
Authors: Dillamore Adam M , Belokurov Vasily , Font Andreea S , McCarthy Ian G
Published: April 2022

Using the artemis set of 45 high-resolution cosmological simulations, we investigate a range of merger-induced dynamical transformations of Milky Way-like galaxies. We first identify populations of accreted stars on highly radial orbits, similar to the ‘Gaia Sausage’ in the Milky Way. We show that ≈1/3 of the artemis galaxies contain a similar feature, and confirm that they usually comprise stellar debris from the most massive accreted satellite. Selecting 15 galaxies with discs at the present-day, we study their changes around the times of the GS-like mergers. Dark matter haloes of many of these exhibit global changes in shape and orientation, with almost half becoming significantly more spherical when the mergers occur. Focusing on the galaxies themselves, we find that 4/15 have stellar discs which experience large changes in the orientation of their angular momentum (AM) axes, at rates of up to ∼60 degrees Gyr−1. By calculating the orbital angular momentum axes of the satellites before they are accreted, we show that there is a tendency for the disc’s AM to become more aligned with this axis after the merger. We also investigate the origin of in situ retrograde stars, analogous to the ‘Splash’ in the Milky Way. Tracing them back to earlier snapshots, we demonstrate that they were often disrupted on to their extreme orbits by multiple early mergers. We also find that the total mass of these stars outside the central regions positively correlates with the total accreted stellar mass.
On the lower limit of contact binary star periods
Authors: Koen Chris
Published: April 2022

Data for 405 contact binary systems extracted from a recent compilation are supplemented by information from the literature for an additional ten ultrashort period (P < 0.2 d) binaries. This is used to calibrate period–luminosity–temperature relations for contact binaries. The derived relations are applied to a standard mean temperature–luminosity tabulation to obtain predicted periods for contact systems over the spectral range M9.5–A2. Minimum periods in the range 0.08–0.15 d follow, depending on the precise period–luminosity–temperature model fitted.
Characterizing eclipsing white dwarf M dwarf binaries from multiband eclipse photometry
Authors: Brown Alex J , Parsons Steven G , Littlefair Stuart P , Wild James F , Ashley R P , Breedt E , Dhillon V S , Dyer M J , Green M J , Kerry P , Marsh T R , Pelisoli I , Sahman D I
Published: April 2022

With the prevalence of wide-field, time-domain photometric sky surveys, the number of eclipsing white dwarf (WD) systems being discovered is increasing dramatically. An efficient method to follow these up will be key to determining any population trends and finding any particularly interesting examples. We demonstrate that multiband eclipse photometry of binaries containing a WD and an M dwarf can be used to determine the masses and temperatures of the WDs to better than 5 per cent. For the M dwarfs, we measure their parameters to a precision of better than 6 per cent with the uncertainty dominated by the intrinsic scatter of the M dwarf mass–radius relationship. This precision is better than what can typically be achieved with low-resolution spectroscopy. The nature of this method means that it will be applicable to LSST data in the future, enabling direct characterization without follow-up spectroscopy. Additionally, we characterize three new post-common-envelope binaries from their eclipse photometry, finding two systems containing hot helium-core WDs with low-mass companions (one near the brown dwarf transition regime) and a possible detached cataclysmic variable at the lower edge of the period gap.
Bending waves in velocity space: a first look at the THINGS sample
Authors: Nandakumar Meera , Narayan Chaitra , Dutta Prasun
Published: April 2022

Detection of bending waves is a highly challenging task even in nearby disc galaxies due to their sub-kpc bending amplitudes. However, simulations show that the harmonic bending of a Milky Way-like disc galaxy is associated with a harmonic fluctuation in the measured line-of-sight (los) velocities as well, and can be regarded as a kinematic signature of a manifested bending wave. Here, we look for similar kinematic signatures of bending waves in H i discs, as they extend too much beyond the optical radii. We present a multipole analysis of the H i los residual velocity fields of six nearby spiral galaxies from the THINGS sample, which uncovers the bending wave-induced velocity peaks. This allows us to identify the radial positions and amplitudes of the different bending modes present in the galaxies. We find that all of our sample discs show a combined kinematic signature of superposition of a few lower order bending modes, suggesting that bending waves are a common phenomenon. The identified velocity peaks are found to be of modes m = 2, 3, and 4, not more than 15 km s−1 in amplitude and spread across the entire H i disc. Interestingly, they appear to be concentrated near the optical edge of their host galaxies. Also, m = 2 appears to be more common than the other two modes.