bluuebunny/crossref_metadata_2025 huggingface dataset:
WEIGHTED \(S^p\)-PSEUDO \(S\)-ASYMPTOTICALLY PERIODIC SOLUTIONS FOR SOME SYSTEMS OF NONLINEAR DELAY INTEGRAL EQUATIONS WITH SUPERLINEAR PERTURBATION
Authors: El Bazi Hamza , Sadrati Abdellatif
Published: July 2023

This work is concerned with the existence of positive weighted pseudo \(S\)-asymptotically periodic solution in Stepanov-like sense for some systems of nonlinear delay integral equations. In this context, we will first be interested in establishing a suitable composition theorem, and then some existing results concerning the \(S\)-asymptotic periodicity in the scalar case are developed here for the vector case. We point out that, in this paper, we adopt some changes in the definitions, which, although slight, are necessary to accomplish the work.
AN \(M^{[X]}/G/1\) QUEUE WITH OPTIONAL SERVICE AND WORKING BREAKDOWN
Authors: Somasundaram B. , Karpagam S. , Lokesh R. , Kavin Sagana Mary A.
Published: July 2023

In this study, a batch arrival single service queue with two stages of service (second stage is optional) and working breakdown is investigated. When the system is in operation, it may breakdown at any time. During breakdown period, instead of terminating the service totally, it continues at a slower rate. We find the time-dependent probability generating functions in terms of their Laplace transforms and derive explicitly the corresponding steady state results. Furthermore, numerous measures indicating system performances, such as the average queue size and the average queue waiting time, has been obtained. Some of the numerical results and graphical representations were also presented.
Machado Black and Blur
Authors: Monteiro Pedro Meira
Published: July 2023

Atentando para a construção das imagens do autor ao longo do tempo, proponho a inadequação dos procedimentos que pretendem resgatar o “verdadeiro Machado de Assis”. Por meio da discussão de certos passos da fortuna crítica passada e recente, de fotografias, anúncios e de um filme recente, sugiro o alinhamento da perspectiva machadiana às propostas de Fred Moten sobre a natureza oscilante da luta negra, e de Eduardo de Assis Duarte sobre o tratamento indireto da história por Machado.
Correlation of C-Reactive Protein and Severity of Peri-Implant Diseases
Authors: Pradeep Rajasri , Rajasekar Arvina
Published: July 2023

Peri-implant disease pathogenesis is similar to periodontal disease pathogenesis resulting in production of pro-inflammatory mediators. These mediators are released during the inflammation phase, among which C-reactive protein (CRP) is one of the acute phase reactants. The aim of the study was to correlate the levels of CRP with the severity of peri-implant diseases. The present observational study was carried out from June 2022 to December 2022 in the Department of Implantology, Saveetha Dental College and Hospitals, Chennai, India. A total of 60 patients with peri-implant health (n = 20), peri-mucositis (n = 20) and peri-implantitis (n = 20) were enrolled. Unstimulated salivary samples were collected and subjected to latex agglutination assay for CRP analysis. CRP levels were then correlated with severity of peri-implant diseases. The mean CRP level in peri-implant health, peri-implant mucositis, peri-implantitis were 0.25 ± 0.36 mg/dl, 3.56 ± 0.85 mg/dl and 5.07 ± 0.74 mg/dl, respectively. Pearson correlation coefficient analysis revealed a strong positive correlation between CRP and peri-implant parameters suggesting that the CRP level increased as the severity of peri-implant disease increased. CRP level increases with severity of peri-implant diseases and there exists a positive correlation between CRP level and peri-implant parameters. Therefore, CRP can be used as a diagnostic marker for peri-implant diseases.
Comparison of Peri-Implant Health Parameters among Obese and Non-Obese South Indian Population
Authors: M. Kayal V. , Rajasekar Arvina
Published: July 2023

Implant therapy is gaining immense importance in people presenting with missing teeth due to its increased life expectancy. There is a high concern regarding the link between obesity and peri-implant diseases. The aim of this study was to assess the peri-implant health parameters among the obese and non-obese South Indian population. The cross-sectional study was conducted in Department of Implantology, Saveetha Dental College and Hospitals Chennai, India among 859 patients who reported between January 2022-November 2022 and had a minimum of single implant in function for at least 1 year after crown cementation. Among 859 patients, 428 were non-obese (Group A) and 431 were obese (Group B). Patient's data including the menopausal status was recorded. Clinical parameters including peri-implant probing depth (PPD), clinical attachment level (CAL) and radiographic parameter including alveolar bone level (ABL) was recorded and compared between both the groups using independent t-test. The mean PPD among non-obese and obese population were 2.58 ± 0.03 and 4.09 ± 0.04, respectively. The mean CAL among non-obese and obese population were 2.87 ± 0.02 and 4.19 ± 0.01, respectively. The mean ABL among non-obese and obese population were 2.06 ± 0.01 and 3.17 ± 0.03, respectively. Independent t-test revealed there was statistically significant difference in PPD (P = 0.04), CAL (P = 0.05) and ABL (P = 0.04). The present study suggests that the obese individuals demonstrated high peri-implant probing depth, clinical attachment loss and alveolar bone loss as compared to non-obese individuals.
Cellular lipid uptake with flow cytometry readout v1
Authors: Beletchi Igor
Published: July 2023

Cellular lipid uptake with flow cytometry readout
A NEW ACQUISITION PROTOCOL FOR CONDUCTING STUDIES WITH CHILDREN: THE SCIENCE CAMP RESEARCH EXPERIENCE v1
Authors: V. Marquez-Garcia Amparo
Published: July 2023

In the last 50 years, the study of brain development has brought major discoveries to education and medicine, changing the lives of millions of children and families. However, collecting behavioral and neurophysiological data from children has specific challenges, such as high rates of data loss and participant dropout. We have developed a science camp method to collect data from children using the benefits of positive peer interactions and interactive and engaging activities, to allow researchers to better collect data repeatedly and reliably from groups of children. A key advantage of this approach is that by increasing participant engagement, attention is also increased, thereby increasing data quality, reducing data loss, and lowering attrition rates. This protocol describes the step-by-step procedure for facilitation of a science camp, including behavioral, electrophysiological, and participatory engagement activities. As this method is robust but also flexible, we anticipate that it can also be applied to different demographics and research needs.
MicroMPN:Software for Automating Most Probable Number Estimates from Laboratory Microplates v1
Authors: R Rivers Adam
Published: July 2023

We developed a command-line Python package named "MicroMPN" to enable the automation of most probable number (MPN) value estimations from microplates of different formats and sample designs. In this protocol, we guide users on how to run MicroMPN from a Jupyter Notebook using simulated fluorescence data values. To run MicroMPN, the users must input two data files. Input file 1: the user provides a CSV file with the plate name, the well locations of each samplein a microplate, and the spectrofluorometric data. Input file 2: the user specifies the layout of a microplate with a Wellmap TOML-based format file. The second file contains the number of replicates, the dilution series, and the number of samples per plate. The Python package “wellmap” parses the information of a microplate from the TOML formatted file for downstream calculation of an MPN value. Additionally, users must specify a cutoff/threshold value, which is used to determine which wells are positive or negative for microbial growth. Output file: MicroMPN will calculate an MPN value, a bias-corrected MPN value, 95% confidence intervals, and a rarity index.
Human urine procurement and processing v1
Authors: not provided hannah.anvari
Published: July 2023

Purpose: This protocol is intended for use in the collection and storage of human urine in a research setting. The protocol details the collection, processing, and long-term storage for downstream analysis alongside other tissues or samples of interest (i.e. follicular fluid, ovary).
Co-culture leukemia high-content image analysis using supervised machine learning v1
Authors: L Bell Hayden
Published: July 2023

This protocol describes a non-informatics based approach to high-content image analysis of acute leukemia cells in co-culture with mesenchymal stromal cells (MSCs) using supervised machine learning. The analysis pipeline leverages two powerful, open-source software applications - Cell Profiler and Ilastik. The aim of this protocol is to provide a basic skeleton pipeline for image analysis to, at minimum, determine absolute cell numbers for each cell class from a fluorescence microscopy image of cells stained with a DNA dye. This protocol is a detailed companion walkthrough for the Github repository available at https://github.com/hayden-bell/Image_Analysis.
Cell surface biotinylation v1
Authors: not provided rosanne.wouters
Published: July 2023

The protocol describes cell surface biotinylation to identify plasma membrane localized proteins in cell culture via western blotting.
Çatalca-Binkılıç yöresindeki sürgün kökenli meşe koru ve baltalık ormanlarının odun verimi açısından karşılaştırılması
Authors: ÖZER Gülçin , AKALP Tahsin
Published: July 2023

Bu çalışmada, Çatalca-Binkılıç Orman İşletme Şefliği’ne ait sürgün kökenli koru ve baltalık ormanlarının odun verimi karşılaştırmalı olarak incelenmiştir. Odun verimini tespit için amenajman planı verileri kullanılmış; geçici örnek alanların ölçümleriyle de amenajman planı verilerinin uygunluğu denetlenmiştir. Baltalıkta yaş-hacim ilişkisi, ayrılan ve kalan meşcere hacimleri ile genel hacim verimi belirlenmiş; Eraslan’ ın (1954), odun çeşitleri tablosu kullanılarak meşcere hacimlerinin tomruk, maden direği ve yakacak odun ürün çeşitlerine dağılımı bulunmuştur. Tomruk “100” olmak üzere fiyat endeksleri maden direği için “80” ve yakacak odun için “15,5” hesaplanmış ve böylece her yaş ve ürün çeşidi için fiyat endeksleri belirlenmiştir. 120 yıllık idare süresi sonunda fiyat endeksi baltalıklar için 4548; koru ormanları için ise bunun 5 katına yakın bir değer olarak 19282 bulunmuştur.
The Anatomy and Morphology of Taenitis Willd. ex Sprengel (Monilophytes) in Peninsular Malaysia
Authors: Haja Maideen Haja Maideen , Nurul Nadhirah Nurul Nadhirah , Nur Aliah Nur Aliah , Nik Norhazrina Nik Norhazrina
Published: July 2023

The present study investigates the anatomical and morphological characteristics of four Taenitis species sampled from several localities in Peninsular Malaysia, namely Taenitis blechnoides, T. interrupta, T. dimorpha and Taenitis sp. The morphological and anatomical characters were observered with compound and dissecting microscopes, and sliding microtome. The species exhibited varying frond sizes (length and width) and positions of sori. Conversely, all the species showed common short creeping rhizomes with black hairy scales, scales at the base of stipes, U-shaped steles, simple trichome, sclerenchyma cells under the epidermis on stipes and rhizomes, polocytic stomata, and sinuous anticlinal walls. Morphologically, the frond form of Taenitis sp. is distinct from the other Taenitis. Thus, the species could be a new record for ferns in Peninsular Malaysia. However, molecular studies are required to confirm this.
Toxicity of Clove Oil Nanoparticles against Diamondback Moth Plutella xylostella (L.)
Authors: Silvi Ikawati Silvi Ikawati , Abdul Choliq Fery
Published: July 2023

Plutella xylostella, diamondback moth (DBM), has been one of the most challenging insects to control in the world to date. Environmentally friendly methods of control, such as the use of botanical insecticides, are available. A formulation that can sustain the main compound's level is required, which can be accomplished through soluble powder nanoformulation. The goal of this research was to test and evaluate the ability of clove oil nanoparticles produced from polyethylene glycol 6000 (PEG 6000) to control DBM utilizing a solid dispersion technique. Bioassay by leaf dip method in laboratory was used to test the lethal effect of clove oil nanoparticles (CO-NPs) on DBM. Clove oil nanoformulation was successful because it produced nanoparticles (179.98 nm in diameter) while maintaining high levels of the active component eugenol. Clove oil nanoparticles may increase clove oil's toxicity to DBM, seen from the LC50 value after 24 h of treatment. The LC50 values for clove oil nanoparticles after 24 and 48 h of treatment were 10.308 and 9.451%, respectively.
Filem Mikrosfera Akrilik Terpegun Alizarin Merah S untuk Pengesanan Pendarfluor Optik Asid Bori
Authors: Raja Jamaluddin Raja Zaidatul Akhmar , Ahmad Musa , Lee Yook Heng , Tan Ling Ling
Published: July 2023

Mikrosensor pendarfluor optik untuk kuantifikasi asid borik dalam sampel makanan telah dibangunkan berdasarkan filem mikrosfera poli(n-butil akrilat) [poli(nBA)]. Pencirian optik reagen alizarin merah S (ARS) terpegun pada filem mikrosfera poliakrilat dengan asid borik telah dilakukan melalui pendekatan transduksi pendarfluor. Reagen ARS telah dijerap secara fizikal pada filem mikrosfera akrilik hidrofobik untuk membentuk mikropolimer kelat dengan sokongan matriks sol-gel untuk mengelakkan larut lesap molekul ARS yang bersifat larut air. Pengkelat ARS yang terpegun pada filem mikrosfera poli(nBA) memberikan tindak balas pengesanan optik yang cepat dalam masa 1 minit. Julat rangsangan linear dinamik yang berguna bagi mikrosensor pendarfluor optik asid borik telah diperoleh antara 1.6 µM dan 32.0 µM asid borik dengan had pengesanan (LOD) pada 1 μM. Mikrosensor pendarfluor optik asid borik berasaskan mikropolimer akrilik menghasilkan prestasi kebolehulangan yang baik dengan nilai sisihan piawai relatif (RSD) yang dicapai dalam julat 3.3-3.6%. Mikrosensor optik yang dibangunkan telah digunakan untuk pengukuran pendarfluor asid borik dalam sampel mi kuning dan mi beras leper ('hor fun'/'kway teow') dan tidak menunjukkan perbezaan yang ketara berbanding dengan kaedah rujukan tradisional spektrometri pemancaran plasma-optik berganding secara induktif (ICP-OES).
Effect of Alkali Treatment and Fibre Composition on the Performance of Pineapple Leaf Fiber-Polyvinyl Alcohol Composites
Authors: Zubairi Hanis Nurafiqah , M. Salleh Noordini , Abd Rahman Nor Mas Mira
Published: July 2023

This paper studied the properties of composites based on polyvinyl alcohol reinforced with pineapple leaf fibres (PALF/PVA). The surface of pineapple leaf fibres (PALF) has been previously treated with 6% sodium hydroxide solution. The influence of fibre loading and fibre surface treatment were examined. Analysis by Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD) displayed physico-chemical changes on treated PALF/PVA composites compared to untreated PALF/PVA composites. The results from thermogravimetric analysis (TGA) showed that the introduction of untreated PALF into the composites enhanced the thermal stability of the composites. Progressive improvement of thermal stability was discovered by associating treated PALF with the composites. The treated PALF composites produced also improved mechanical properties with increasing fibre content. Differential scanning calorimetric (DSC) analyses showed no significant changes in melting temperatures upon incorporating untreated PALF into the PALF/PVA composites. The best improvement in tensile strength value was obtained for treated PALF composite having 3 wt% of fibre loading, with enhancements of about 11% and 54%, compared to untreated PALF composites and plain PVA matrix, respectively.
Proportion of CD44+ Subset of Tumour Cells in Single Cell Suspension Prepared from FFPET Sections Directly Correlates with Histological Subtyping of Head and Neck Squamous Cell Carcinoma
Authors: Muhammad Kashif Muhammad Kashif , Sadia Minhas Sadia Minhas , Shah Jahan Shah Jahan , Afra Samad Afra Samad , Faheem Shahzad Faheem Shahzad , Romeeza Tahir Romeeza Tahir , Abdul Hanan Nagi Abdul Hanan Nagi , Nadeem Afzal Nadeem Afzal
Published: July 2023

CD44 expression in tumours imparts potential to progress, metastasize, recurrence, and resistance against antineoplastic therapy. In this study, we sought to describe the variation in the immuno-expression and numeration of MDR1+ and CD44+ potential cancer stem cells in different histological grades and subtypes of head and neck squamous cell carcinoma (HNSCC). Flow-cytometric analysis was performed on single cell suspension prepared from formalin fixed paraffin embedded tissue (FFPET) sections of HNSCC using anti-CD44 and anti-MDR1/ABCB-1 primary monoclonal antibodies. Immunohistochemical (IHC) staining was also carried out using both of these antibodies on HNSCC tissue sections mounted on super frosted glass slides. On immunohistochemical analysis, the mean IRS for CD44 and MDR1 were 8.6364 ±3.02114 and 1.5909 ±1.27674 respectively. When mean immune-expression scores of CD44 antibody and MDR1/ABCB-1 were compared with histological grades and subtypes of HNSCC, the relationship was found to be statistically insignificant. Interestingly, a strong statistical difference (p = 0.000) was observed when the mean score of subset of dysplastic squamous epithelial cells with characteristics of cell stemness (CD326+CD44+) was compared among different histological subtypes of HNSCC using flowcytometric analysis. While no statistically significant association was observed when the mean score for subset of dysplastic cells with potential of drug resistance (CD44+MDR1+) was compared among different histological subtypes of HNSCC. Although potential cancer stem cell marker CD44 and the multidrug resistance maker ABCB-1/MDR1 co-expressed in HNSCC but the proportion of CD326+CD44+ subset of tumour cells (potential cancer stem cells/CSCs) significantly correlates with least aggressive to more aggressive tumour subtypes.
A Scoping Review on Determinants of Active Ageing in Southeast Asian Region
Authors: Salih Sarah , Hamid Tengku Aizan , Ibrahim Rahimah , Ashari Asmidawati , Abdullah Siti Farra , Chai Sen Tyng
Published: July 2023

Many developing countries face a rapidly ageing population requiring sufficient preparation to integrate various services for enhancing healthy active ageing. However, there is a lack of evidence on the comprehensive framework of active ageing and its overall determinants, especially in the Southeast Asia region. The current review sought to understand the main determinants of active ageing to predict the indicators of active ageing in the Southeast Asia region. A scoping review is conducted by reviewing English language literature published between 2002 and 2022 in three electronic databases, including Scopus, ScienceDirect, and PubMed, using MeSH terms, keywords, and inclusion and exclusion criteria. The review found a wide range of variables related to five determinants of healthy ageing in Southeast Asia. Participation in social, physical, learning, and labour activities is the most frequent and popular determinant of active ageing in Southeast Asia. Followed by health (health services and health status), perceived environment (neighbourhoods and housing), security (financial security, social status, and independency), behavioural (spirituality and lifestyle), and personal demographic characteristics, respectively. Overall, this scoping review contributed to the identification of comprehensive indicators ofactive ageing in Southeast Asia, including Malaysia.
Gel Mengandungi Nanopartikel Kitosan yang Dimuatkan dengan DsiRNA dan Kurkumin sebagai Pembalut Luka Kencing Manis: Pelepasan Bahan Aktif dan Kesan Sitotoksik
Authors: Mohd Fadhil Fatin Hanani , Ng Shiow-Fern , Katas Haliza
Published: July 2023

Baru-baru ini, RNA penghalang kecil substrat-Diser (DsiRNA) telah digabungkan dengan satu agen anti-radang semula jadi iaitu kurkumin (Cur) dalam bentuk nanozarah dan dimuatkan ke dalam gel untuk rawatan luka kencing manis. DsiRNA telah digunakan untuk melenyapkan ekspresi berlebihan gen pembawa prostaglandin (PGT) yang mengganggu respons pembentukan salur darah dan melambatkan penyembuhan luka. Selain sifat fizikokimia, keberkesanan dan keselamatan formulasi ini juga bergantung kepada corak pelepasan bahan aktif. Oleh itu, kajian ini telah menilai corak pelepasan bahan aktif daripada nanozarah dan gel tersebut serta kesan kesitotoksikannya. Dalam kajian ini, kedua-dua bahan aktif ini telah dimasukkan ke dalam nanozarah kitosan (CSNPs) menggunakan kaedah gelasi ion dan kemudiannya dicampur ke dalam pembawa gel Pluronik F-127 (PF-127) pada kepekatan berbeza. CSNPs yang terhasil telah dioptimumkan untuk memperoleh zarah bersaiz kecil (301.3 ± 57.6 nm) dan cas permukaan yang tinggi (+23.7 ± 0.7 mV). Kebanyakan zarah adalah berbentuk sfera dengan keberkesanan pemerangkapan yang tinggi untuk Cur (86.8 ± 4.2%) dan DsiRNA (100.9 ± 52.5%). Gel yang terhasil pula mempunyai tekstur dan morfologi gel yang baik dan sesuai untuk aplikasi topikal. Kajian pelepasan dadah selama 24 jam secara in-vitro menunjukkan jumlah kumulatif pelepasan DsiRNA adalah lebih tinggi berbanding Cur iaitu dalam lingkungan 23.8-35.4 µg/cm2. Kebolehidupan fibroblas yang didedahkan kepada formulasi ini juga adalah melebihi 80%, menggambarkan sifat tidak toksik CSNPs terhadap sel. Kesimpulannya, formulasi gel yang mengandungi CSNPSs ini berpotensi untuk dibangunkan sebagai pembalut luka dan agen penyembuh luka kencing manis.
Visually Impaired Persons and Social Encounters in Central Melbourne
Authors: Pourafkari Shirin
Published: July 2023

Urban spaces are areas where routes, activities, and people, including visually impaired persons (VIPs), intersect. Most urban research on VIPs focuses on wayfinding. However, the experience of urban spaces is not limited to utilitarian functions and also includes people’s lived experiences and random social encounters. To understand how a broader range of activities, experiences, and encounters may be better enabled, VIPs have participated in multi-method research including interviews, word games, walking interviews, and diary recordings in central Melbourne. Results not only indicate a broad range of unmediated conflicts between VIPs’ mobility needs and key aspects of intense street life but also reveal opportunities that are potentially hidden in random encounters in public spaces.
Planlamada Açık Veri Portalları/Etkileşimli Haritalar: İzmir (Türkiye) - Sidney (Avustralya) Örneği
Authors: ÖZBEK Tuğçe Nida Nur , ERCOSKUN Ozge
Published: July 2023

Uluslararası boyutta giderek artan açık veri girişimleri gerçekleşmektedir. Hükümetler bu girişim kapsamında büyük ölçekte ve detayda veri toplamakta ve/veya üretmektedir. Bu verilerin açık erişimde ve yeniden kullanılabilir formatlarda yayınlanmasını sağlayabilmek adına açık veri portalları oluşmuştur. Bu nedenle çok sayıda açık veri havuzu, katalog, haritalama sistemi ve portal ortaya çıkmıştır. Coğrafi (mekânsal) işaretleme dili ile çevrimiçi erişilebilen içeriklere, görüntülenebilir ya da indirilebilir veriler olarak rastlanmaktadır. Birlikte çalışabilir ve bağlanabilir açık verilerin daha fazla mevcudiyeti, bu tip verilerin ikincil kullanımını katalize etmektedir. Başarılı açık veri portallarının verimli bir şekilde kullanılabilmesi ve geliştirilebilmesi için gerekli iyileştirmelerin sistematik biçimde değerlendirilmesini gerekli kılmaktadır. Bu nedenle bu çalışma özellikle açık veri portalları alanına yönlendirilmiştir ve ulusal açık veri portalının kullanılabilirliğinin analizine odaklanmaktadır. Çalışmanın amacı ulusal ve uluslararası düzeyde seçilmiş kentlerin açık veri portallarını karşılaştırmak ve bu portalların kalitesini daha da artıran yeni bir değerlendirme çerçevesi önermektir. Bu nedenle yoğunluklarının benzer olmasının göz önünde bulundurulduğu örneklem olarak seçilen kıyı kentlerinden İzmir ve Sidney’in sahip olduğu açık veri portallarının içerik analizi yapılarak sağlanan veri kümelerini ve nasıl paylaşıldığını değerlendirmek çalışmanın merkezinde yer almaktadır.
Low-temperature properties of fuel blends based on biodiesel derived from frying oil wastes
Authors: Krivtsov Sergey N. , Krivtsova Tatiana I. , Kovaleva Nadezhda I.
Published: July 2023

BACKGROUND: Automotive engines are one of the environment pollutants with harmful substances and greenhouse gases. Recently, the field of carbon-free or carbon-neutral energy has become the most relevant. In this regard, the task of reducing the carbon footprint of automotive equipment equipped with internal combustion engines remains urgent. This can be done by complete or partial replacement of the fuel with the carbon-neutral one, such as plant-origin biofuels.
AIMS: Study of low-temperature properties of fuel blends based on biodiesel derived from frying oil wastes.
MATERIALS AND METHODS: The vegetable oil ether was derived from purified frying oil wastes by esterification. Then fuel blends were obtained by mixing the derived ether with diesel fuel of different brands and butanol. The study of viscosity-temperature properties and density of the obtained fuel blends was carried out in the temperature range from -20C to 40C. The methods and equipment for determining these parameters meet the requirements of GOST.
RESULTS: The obtained study results helped to conclude that blended biodiesel in certain proportions can be used as fuel even at negative ambient temperatures, which is not uncommon for the start of a sowing campaign in spring and the end of field work in autumn in sharply continental climatic conditions.
CONCLUSIONS: The practical value of the study lies in the possibility of using fuel blends based on biodiesel derived from frying oil wastes at low temperatures.
The mathematical model of turning kinematics of a two-section active road train with real and ideal control systems of semitrailer wheels turning
Authors: Godzhaev Zahid A. , Kapitonov Mikhail V.
Published: July 2023

BACKGROUND: The development of aerospace machinery leads to the need for transportation of increasingly large-sized indivisible cargo by ground vehicles. At the same time, taking into account the peculiarities of the transported cargo, a number of special requirements including maneuverability are imposed on vehicles.
AIMS: Defining the magnitude of the semitrailer path offset relative to the truck path.
METHODS: The solution of the system of ordinary differential equations is performed using the MATLAB/Simulink software implementing the Runge-Kutta-Felberg method of the fourth-fifth orders.
RESULTS: The comparative graph of the values of the normal and ideal jack-knifing angles has been obtained.
CONCLUSIONS: The developed mathematical models and calculation software make it possible to assess the maneuverability of newly developed prototypes quite quickly and accurately.
Results of surgical treatment of patients of fertile age planning pregnancy with hernias of the anterior abdominal wall
Authors: Sigua Badri V. , Semin Dmitrii S. , Gurzhiy Dmitrii V. , Kozobin Alexander A. , Zemlyanoy Vyacheslav P.
Published: July 2023

BACKGROUND: Currently, there is no consensus and approved tactics for choosing the method of hernioplasty in the surgical treatment of patients of fertile age planning pregnancy with hernias of the anterior abdominal wall. The study is devoted to the comparative analysis of surgical treatment of these patients.
AIM: To determine the algorithm of surgical treatment of hernias of the anterior abdominal wall in the patients of fertile age planning pregnancy.
MATERIALS AND METHODS: The analysis of the treatment results of fertile age patients with hernias of the anterior abdominal wall in the period from 2010 to 2019 has been carried out. The inclusion criteria were as follows: patients of fertile age who underwent surgical treatment of hernias of the anterior abdominal wall, who did not have a relapse before pregnancy. Thus, 252 patients have been included in the study.
RESULTS: The surgical tactics and optimal timing of the operation in patients of fertile age with hernias of the anterior abdominal wall have been determined.
CONCLUSIONS: When planning surgical treatment of hernias of the anterior abdominal wall in patients of fertile age, it is necessary to clarify information about pregnancy planning. The most favorable period for planning pregnancy and childbirth is 3 years or more after hernioplasty. When planning a pregnancy in the next 12 years after surgical treatment of a ventral hernia, it is necessary to give preference to hernioplasty with local tissues, which has fewer complications in the long-term postoperative period as well as fewer relapses after childbirth compared with open prosthetic surgery. When planning a pregnancy 3 or more years after surgical treatment, preference should be given to prosthetic hernioplasty. When analyzing the results of treatment of the patients of fertile age with inguinal and femoral hernias, planning pregnancy, clinical experience has shown that there are no contraindications to performing laparoscopic transabdominal preperitoneal prosthetic hernioplasty.
New approaches to pathogenetic anti-inflammatory therapy of cardiovascular diseases
Authors: Kolesova Ekaterina P. , Maslyanskiy Alexey L. , Rotar Oxana P. , Konradi Alexandra O. , Mazurov Vadim I.
Published: July 2023

In recent years, new data have been obtained confirming the role of inflammation as the leading pathogenetic mechanism for the development of atherosclerosis and its complications. In addition, atherosclerosis is considered in the spectrum of atypical autoinflammatory diseases.
The aim of the paper is to highlight the role of inflammation in the development and progression of atherosclerosis and other cardiovascular diseases as well as to identify new therapeutic targets for the treatment of cardiovascular disease.
The search has been performed in the PubMed, e-library, Embase, ClinicalTrials.gov databases, using the keywords: inflammation, NLRP3 inflammasome, TNF-, IL-1 blocker, atherosclerosis, cardiovascular disease. As a result, 210 references have obtained; the results of 15 clinical studies have been selected for the final analysis as well as 15 papers containing the results of original studies with access to the full text articles in Russian or English.
The analysis of literature sources revealed that inflammation plays a crucial role in the development of cardiovascular diseases, and modern anti-inflammatory therapy is a promising, pathogenetically justified strategy for the prevention and treatment of cardiovascular diseases.
The role of plasminogen and urokinase activator of plasminogen in the treatment of endogenous uveitis in children
Authors: Katargina Ludmila А. , Chesnokova Natalya B. , Denisova Ekaterina V. , Khrabrova Mariia A. , Beznos Olga V.
Published: July 2023

AIM: To determine the content of plasminogen and urokinase activator of plasminogen in tears and blood serum and to identify correlations between the studied parameters and the clinical picture of uveitis.
MATERIAL AND METHODS: One hundred thirty-three eyes with uveitis were examined in 74 patients aged 3 to 17 yr (average 10.453.35 yr). The content of the urokinase activator of plasminogen (UPA) was studied in 188 tear samples and 22 blood serum samples. The dynamics of UPA in tears were studied in 28 patients (51 eyes). The plasminogen content of 86 tear samples and 34 blood serum samples was studied. The dynamics of plasminogen in tears were studied in five patients (nine eyes). The concentrations of UPA and plasminogen were measured using the ELISA method and the kits ELISA kit for plasminogen activator, urokinase (UPA)/ELISA Kit for Plasminogen, Cloud-Clone Corp., USA).
RESULTS: An increase in the content of UPA in the tears of children with uveitis was associated with higher inflammatory activity (p=0.04). An increase in the content of UPA in tears was associated with an increase in the degree of proliferative changes (p=0.04). An increase in the content of UPA and plasminogen in tears was found 12 months after surgery. There was an increase in the content of UPA (p=0.0001) and plasminogen in tears (p=0.009) and blood serum (p=0.09) with age.
CONCLUSION: The content of UPA in tears increased significantly when severe uveitis was compared with inactive uveitis. An increase in the content of UPA in tears was associated with an increase in the degree of proliferative changes, which reflects the severity of the uveitis course. The content of UPA and plasminogen in tears and blood serum increased with age. An increase in UPA and plasminogen was observed within 12 months after surgery, with both returning to preoperative values by the third month of the postoperative period, which reflects the normal course of the wound healing process.
Clinical features, diagnosis, and treatment of dry eye syndrome in children
Authors: Filatova Irina A. , Kondratieva Julia P. , Shemetov Sergey A. , Trefilova Marina S.
Published: July 2023

Ptosis of the upper eyelid remains the most common pathology of the auxiliary apparatus of the eye in children and adults alike. Presently, there are no methods of pharmacological correction for the omission of the upper eyelid; hence, only surgical treatment is available. However, the recommended surgery has been associated with unsatisfactory outcomes in 826% of all patients. There are several directions of surgical treatment of blepharoptosis, depending on the main cause of its development and degree, such as operations on the muscle that raises the upper eyelid (levator resection, recession, levatoroplasty with the formation of a duplicate of the levator) and its tendons (aponeurosis); operations on the tarsal plate; and suspension type operations. Despite the large number of approaches to surgical treatment available for blepharoptosis they are associated with a high risk of hypo and hyper side effects. Therefore, it is not always possible to eliminate the existing changes or damage in different types of ptosis, which may raise the need for a reoperation, which is quite complicated. The standard linear methods for determining the biometric parameters of the mobility of the upper eyelid and degree of ptosis conducted in the preoperative period do not always result in good outcomes. In fact, no reliable criteria allow the prediction of the outcome of surgical treatment with a high degree of probability and planning the volume of surgery. Therefore, it is extremely likely that the addition of dynamometric analysis of the contractile activity of the upper eyelid lifting and tarsal muscles to the scheme of preoperative diagnosis of blepharoptosis, as well as the continuation and intensification of research aimed at creating the doctrine of the pathomorphology of upper eyelid prolapse in the future, will serve as the key factors contributing to the improvement of the results of surgical treatment of blepharoptosis.
Inteligencia emocional en población adulta: medición y correlatos, una revisión sistemática
Authors: Moreyra Ruiz Miluska Glamis , Olivas Ugarte Lincol Orlando
Published: July 2023

En esta investigación se buscó identificar los mejores instrumentos disponibles para medir la inteligencia emocional, y esclarecer las relaciones de este constructo con otras variables relevantes en población adulta, a partir de una sistematización de la literatura científica producida en la última década. Por eso, se seleccionó una muestra de 74 artículos científicos publicados entre los años 2012 y 2022 en revistas indexadas en las bases de datos Scopus, Scielo, EBSCO, ProQuest y Redalyc. Entre los principales hallazgos se encontraron 13 instrumentos con adecuadas evidencias de validez y confiabilidad. Asimismo, la inteligencia emocional se relaciona con 49 variables, y en la mayoría de estudios se asocia con el sexo. En conclusión, los test más recomendables para medir la inteligencia emocional en adultos son TMMS-24, WLEIS y EQ-i. Además, esta variable se relaciona directamente con el rendimiento académico y la resiliencia, e inversamente con la depresión, la ansiedad y el estrés.
Influencia de los factores actitudinales hacia la pandemia COVID19 como predictor de la autoeficacia académica en ingresantes de Psicología
Authors: Cubas Romero Taniht Lisseth
Published: July 2023

La autoeficacia académica ha sido uno de los elementos fundamentales en la influencia de los factores actitudinales hacia la pandemia por la COVID19. La presente investigación tuvo como objetivo establecer una relación entre los factores actitudinales como predictores de la autoeficacia académica en ingresantes a la carrera de Psicología en una universidad privada en Lima. Metodología: Se tuvo una muestra de 187 estudiantes pertenecientes al primer ciclo de la escuela de Psicología. Bajo un diseño no experimental descriptivo correlacional. Se utilizaron instrumentos como el Cuestionario de actitudes hacia la pandemia COVID19 y la Escala de Autoeficacia percibida específicas en situaciones académicas – EAPESA. En cuanto a la correlación, el valor del coeficiente de determinación (R cuadrado= 0.51), indica que los factores actitudinales influyen en un 5.1% en variación a la autoeficacia académica. Y en cuanto a la regresión lineal, se estableció un modelo de predicción de la autoeficacia académica, teniendo en cuenta los siguientes datos Y1= 18.427 + .97 (Factores actitudinales). Finalmente, se concluye que los factores actitudinales no predicen de manera significativa la autoeficacia académica.
Study of cord blood lipid profile of term (appropriate and small for gestational age) and preterm (appropriate and small for gestational age) newborns with special reference to atherogenic index: a cross-sectional study
Authors: Kumar Neeraj , Manazir Ali Syed , Abqari Shaad
Published: July 2023

Background: Atherosclerotic cardiovascular diseases is a major cause for morbidity and mortality in adult population. Increasing awareness about the origin of the atherosclerosis in early life has renewed interest in determination of various lipid fractions in paediatric age group. Therefore, the present study was planned to estimate the lipid levels in Term (Appropriate and small for Date) and Preterm (Appropriate and Small for Date) newborn as well to plan meticulous follow-up of babies with a deranged profile. Aim was to study cord blood lipid profile of term and preterm (appropriate and small for date) newborns with special reference to atherogenic index.
Methods: This cross-sectional study was conducted at neonatal section of department of paediatrics in collaboration with department of obstetrics and gynaecology and Rajiv Gandhi centre for diabetes and endocrinology Jawaharlal Nehru medical college, Aligarh Muslim University. A total of 200 newborns were enrolled in the study. Cord blood samples were collected from placental side at birth and analysed for lipid profile which includes total cholesterol, triglycerides, low density and high-density lipoprotein and atherogenic index.
Results: All the lipid parameters were higher among the low-birth weight babies when compared with the normal birth-weight babies, the difference was statistically significant for total cholesterol, triglyceride, HDL and VLDL cholesterol.
Conclusions: Prematurity is a factor associated with a more Atherogenic lipid profile is reaffirmed and SGA as an additional risk factor has been proven giving scope for future research and primordial prevention.
Cryptococcal antigenemia in a Nigerian child with advanced HIV disease: a case report
Authors: Ekeng Bassey E. , Nwankwo Grace I. , Adedokun Olufunke F. , Bassey Glory E. , Ide Christian , Okorafor Linda N. , Essien Kingsley A. , Oladele Rita O.
Published: July 2023

Cryptococcal infection in Nigeria’s advanced HIV disease (AHD) population is not uncommon but is sparsely reported in children. The dearth of data on cryptococcal disease in our paediatric population suggests it is an uncommon clinical entity and may cause delayed diagnosis and preventable deaths. It is pertinent that cognizance be done of this clinical entity in our paediatric population. We report a 16-month-old HIV-positive child with complaints of weight loss of 3 months, cough of 1 month, fever, passage of watery stool, fast and difficulty in breathing for 1 week. She was initially managed as a case of paediatric AIDS with septicaemia and was receiving ceftriaxone and cotrimoxazole. The diagnosis was subsequently reviewed to paediatric AIDS with cryptococcal disease as the cryptococcal antigen screening test was positive and oral fluconazole commenced. However, the patient deteriorated and eventually died. This case report suggests a significant knowledge gap in the occurrence of cryptococcosis in our paediatric population and as a matter of urgency the need to conduct studies targeted at ascertaining the burden of cryptococcosis in children living with AHD in Nigeria.
A case of permeant neonatal diabetes with KCNJ11 mutation
Authors: V. Renjish , Cherian Carol Sara , Abraham Jacob , Koshy Shanty Mary , Philiip Rajeev
Published: July 2023

Neonatal diabetes mellitus is considered when there is hyperglycaemia requiring insulin therapy. Phenotypically NDM is classified into three types-transient, permanent and syndromic forms. Permanent NDM-may start in new-born life and is mainly due single gene mutations-KCNJ11 and ABCC8. This mutation is almost 90% manageable with oral sulphonyl ureas. We report a case of Permanent NDM with KCNJ11 mutation who presented in diabetic Ketoacidosis at 4 months of age. Clinical genome sequencing revealed a heterozygous missense variation in exon 1 of the KCNJ11 gene (chr11: g.17387491G>A) that results in the amino acid substitution of cysteine for arginine at codon 201. She was initially treated with insulin for which she had poor glycaemic control. She responded well following the switch over to sulphonylureas with good compliance and has normal development.
Rising incidence of malignancy in thyroid nodule: a clinico radio pathological evaluation
Authors: Kapoor Abha A. , Anand Akash M. , Nimkar Nimisha U. , Soni Hiren D. , Panchal Rutul B. , Kapoor Abhay A.
Published: July 2023

Background: Thyroid nodules are a common endocrine problem with varied aetiology and presentation. Benign nodules also need to be evaluated in detail for possibility of malignancy in today’s era of rising incidence of malignancy. This study aims to comparatively analyse and verify the incidence of malignancy reported in tertiary care hospital with incidence of malignancy published in standard journals and research. The study also endeavours to clinically examine solitary thyroid nodules in patients admitted to the tertiary care centre.
Methods: A retrospective study was carried out from 2019 to 2022, in the Department of ENT, in a Tertiary Care Hospital. Thirty patients, with solitary thyroid nodule, were clinically examined and investigated using ultrasonography and Fine Needle Aspiration Cytology, before undergoing hemi/total thyroidectomy. The histopathological reports and pre-operative investigations were analysed by standard statistical methods.
Results: Clinically detected solitary thyroid nodule turned out to be malignant in 30% of studied cases with preponderance of papillary carcinoma. This figure is significantly higher than most of the previous data published in standard journals. A rare case of cystic presentation of anaplastic thyroid carcinoma was also studied.
Conclusions: It is concluded from the present study that incidence of malignancy has shown sharp rise- from the published average of 19-21 percent to 30 percent in the present case. The study also infers that there is female preponderance in thyroid swellings. The mean age of solitary thyroid nodule is 35 years i.e., between 30 to 40 years.
A study on olfactory improvement assessed with butanol threshold test in chronic rhinosinusitis patients after fess at a tertiary care centre in Malabar region
Authors: K. K. Adheela Nusrin , Kizhakkethil Ramachandran , Menon Ashwin M. , Jacob Amal John , Varghese Bindu Sara , Saleem Thasneem
Published: July 2023

Background: Chronic Rhinsinusitis is a hetreogenous disorder with a broad range of etiologic factors involving mucosa of nasal cavity and paranasal sinuses. Olfactory dysfunction has been reported in approximately 60-80% of patients who suffer from CRS.
Methods: Hospital based prospective observational study in the department of ENT, KMCT medical college, Mukkam done in Patients diagnosed with CRS who require FESS having anosmia or hyposmia as an additional symptom. Calculated sample size was 87. Butanol threshold test was done in patients before undergoing FESS and at 1st week,6th week and 24 weeks following FESS and improvement noted. Independent sample t test and ANOVA were used to test statistical significance
Results: Out of 87 subjects, 36% belonged to age group of 36-45 years 15-25 years was the least involved group and majority of patients had nasal obstruction (83.9%) or nasal discharge (81.6%). 69% of patients experienced facial pain and 79.3% had post nasal discharge. Pre operative BTT showed a mean value of 4.89.BTT at 1st week post op showed a mean value of 3.63. At 6 weeks post op BTT value showed significant difference from pre op value with a mean of 2.05 and at 24 weeks post op the mean BTT was 1.70
Conclusions: Summarising the results from our study we affirm that FESS improves olfactory function substantially in CRS patients especially in patients with polyps.
Ossifying fibroma of mastoid: a case report
Authors: Sadath Mohammed , Amadi Ahmad A. , Hammadi Mohammed A. , Busafared Faiza A.
Published: July 2023

Ossifying fibroma is a slow growing benign neoplasm usually Involving bones of the skull and the face, mainly mandible and maxilla. The tumor is composed of bone that develops within fibrous connective tissue, sometimes with cementum-like calcifications. Clinical presentation is usually asymptomatic, rarely presented with facial asymmetry, swelling, pain, bowing of long bones. Radiological investigations are mainly computed tomography (CT) scan and magnetic resonance imaging (MRI). Ossifying fibroma very rarely can be seen as a tumor in temporal bone. In this case report 30-year-old male presented with a history of blocked ear and occasional left ear ache. On examination left externa auditory canal was narrow with bony prominence in the posterior canal wall. CT and MRI revealed left mastoid mass, during surgery hard vascular mass filling the mastoid antrum dissected out and histopathology confirmed as ossifying fibroma. The definitive treatment of ossifying fibroma is complete surgical excision. Complications can be local invasion, intracranial extension.
Intracochlear schwannoma: about a case
Authors: Mercado Martinez Victor , Torres Moyano Francisco , Pino Urrutia Carlos , Fuentealba Bassaletti Constanza , Krishnan Muthaiah Vijaya Prakash , Novoa Cornejo Ignacio
Published: July 2023

Vestibular schwannoma is a benign tumor that originates from Schwann cells. It is most often found in the internal auditory meatus or cerebellopontine angle. Less frequently, intralabyrinthine localization (IL) can be found. These benign lesions usually present with progressive sensorineural hearing loss, tinnitus, and vertigo. Magnetic resonance imaging (MRI) allows a precise diagnosis of these tumors, also defining their exact location within the labyrinth. Currently, the treatment of IL may require radiosurgery, tumor removal surgery, and tumor follow-up with MRI. We will present a clinical case of a patient with intracochlear schwannoma (ICS) of the left ear.