bluuebunny/crossref_metadata_2025 huggingface dataset:
Bat Activity in Organic Rice Fields Is Higher Than in Conventional Fields in Landscapes of Intermediate Complexity
Authors: Boonchuay Ponsarut , Bumrungsri Sara
Published: June 2022

The extent to which organic farming can support biodiversity has been extensively studied. However, most of the research has been conducted on organic farms in temperate regions, with the focus mainly being on birds, insects, and plants and rarely on insectivorous bats, especially in Southeast Asia. We studied pairs of matched organic and conventional rice fields along a gradient of landscape complexity in the Songkhla Lake Basin and conducted acoustic surveys using bat detectors to analyze the influence of farming system and landscape characteristics on bat activity and prey availability. We also tested the “intermediate landscape complexity” hypothesis, which states that local conservation efforts are most effective in landscapes of intermediate complexity compared to extremely simple or extremely complex landscapes. We detected no difference in bat species richness, total bat activity, feeding activity, and insect prey abundance between organic fields and conventional fields. Even though organic farming did not increase bat activity on its own, it was most beneficial to bat activity in landscapes of intermediate complexity. Our findings suggest that landscape traits contribute more to bat activity than farm management and that insectivorous bats have species- and guild-specific responses to various landscape contexts. We also found that disturbance caused by tropical storms negatively impacts the activity of insectivorous bat.
The Influence of c-Kit and NRAS Mutation on Patients’ Survival in Metastatic Melanoma Receiving Immune Checkpoint Inhibitors and Chemotherapy
Authors: Möller Tom , Schulze Hans-Joachim
Published: June 2022

The high metastasis and mortality rates of melanoma in the era of chemotherapy have decreased significantly over the last 10 years. The success is owed largely to the introduction of targeted therapy of oncogenes and immunotherapies, such as checkpoint inhibitors. The aim of the present retrospective, monocentric study is to investigate the impact of chemotherapy or immunotherapy in 550 patients with metastatic melanoma between the years of 2010 and 2019, looking at overall survival while considering BRAF/NRAS/c-KIT mutation status. A total of 17 patients were found to have a c-KIT mutation in exon 11, 13 or 17, including 58.3% with acral lentiginous melanoma, with 53% localized primarily in the lower limbs. In 13.3% of the 231 NRAS-mutated melanomas, primary tumor location was found to be in UV-exposed skin such as on the head and neck, thus about 50% lower than in the 302 patients with wild-type (BRAF-/NRAS-/cKIT-negative) melanoma. Patients with NRAS-mutated melanomas had a significantly lower probability of survival compared to patients with wild-type melanomas, irrespective of the recommendations of the clinical guideline on drug therapy for metastatic melanoma that have been in force since 2010. In contrast to patients with wild-type melanoma who showed a higher probability of survival receiving immune checkpoint inhibitors, the overall survival of patients with NRAS-mutated metastatic melanoma was not more favorable after therapy with immune checkpoint inhibitors compared to chemotherapy treatment.
Modified Immunoscore Improves Prediction of Survival Outcomes in Patients Undergoing Radical Cystectomy for Bladder Cancer—A Retrospective Digital Pathology Study
Authors: Bieri Uwe , Buser Lorenz , Wettstein Marian Severin , Eberli Daniel , Saba Karim , Moch Holger , Hermanns Thomas , Poyet Cédric
Published: June 2022

To evaluate the prognostic value of a modified Immunoscore (mIS) in a cohort of bladder cancer (BC) patients undergoing radical cystectomy (RC), two tissue microarrays of 159 BC patients were immunohistochemically stained for CD3/CD8/FOXP3 and CD45RO to detect Tumor-Infiltrating Lymphocytes (TIL). To predict progression free survival (PFS) and cancer specific survival (CSS), a predictive model cumulatively incorporating all four components was constructed and labeled as mIS. Patients were stratified into two risk groups; “high mIS/favorable risk” and “low mIS/unfavorable risk”. Kaplan–Meier analysis was used to test mIS within each American Joint Committee on Cancer (AJCC) stage group for BC. In a univariable cox regression analysis all single components used for mIS, showed a significant association with CSS. Patients with high mIS (all components) in the AJCC stage IIIa group additionally showed a significantly longer PFS (Hazard Ratio (HR): 2.7; p = 0.008) and CSS (HR: 3.5; p = 0.006) as compared to patients with low mIS. mIS is of prognostic value in BC patients undergoing RC and was able to stratify patients within AJCC stage IIIa and might thus serve as a prognostic marker to guide risk-adapted treatment or follow-up strategies after RC.
Editorial on Special Issue “Spine Imaging: Novel Image Acquisition Techniques and Analysis Tools”
Authors: Sollmann Nico , Baum Thomas
Published: June 2022

Imaging of the spine, including radiography, computed tomography (CT), and magnetic resonance imaging (MRI), is frequently performed in clinical routine [...]
The Utility of Repetitive Cell-Free DNA in Cancer Liquid Biopsies
Authors: Gezer Ugur , Bronkhorst Abel J. , Holdenrieder Stefan
Published: June 2022

Liquid biopsy is a broad term that refers to the testing of body fluids for biomarkers that correlate with a pathological condition. While a variety of body-fluid components (e.g., circulating tumor cells, extracellular vesicles, RNA, proteins, and metabolites) are studied as potential liquid biopsy biomarkers, cell-free DNA (cfDNA) has attracted the most attention in recent years. The total cfDNA population in a typical biospecimen represents an immensely rich source of biological and pathological information and has demonstrated significant potential as a versatile biomarker in oncology, non-invasive prenatal testing, and transplant monitoring. As a significant portion of cfDNA is composed of repeat DNA sequences and some families (e.g., pericentric satellites) were recently shown to be overrepresented in cfDNA populations vs their genomic abundance, it holds great potential for developing liquid biopsy-based biomarkers for the early detection and management of patients with cancer. By outlining research that employed cell-free repeat DNA sequences, in particular the ALU and LINE-1 elements, we highlight the clinical potential of the repeat-element content of cfDNA as an underappreciated marker in the cancer liquid biopsy repertoire.
Cytokine Profile of Invasive Pulmonary Aspergillosis in Severe COVID-19 and Possible Therapeutic Targets
Authors: Russo Alessandro , Morrone Helen Linda , Rotundo Salvatore , Trecarichi Enrico Maria , Torti Carlo
Published: June 2022

During the SARS-CoV-2 pandemic, a higher incidence of invasive pulmonary aspergillosis was observed in patients affected by Coronavirus disease 2019 (COVID-19), leading to the delineation of a new entity named COVID-19 associated pulmonary aspergillosis (CAPA). A predisposition to invasive infection caused by Aspergillus spp. in SARS-CoV-2 infected patients can be ascribed either to the direct viral-mediated damage of the respiratory epithelium, as already observed in influenza H1N1 virus infections, or to the dysregulated immunity associated with COVID-19. This narrative review focuses on the impact of immune impairment, particularly due to cytokine dysregulation caused by Aspergillus spp. superinfection in COVID-19 for a more in-depth understanding of the molecular pathways implicated in CAPA. As immune competence has proven to be essential in protecting against CAPA onset, a role already threatened by SARS-CoV-2 infection itself, preventive strategies should focus on reducing factors that could further target the host immune system. We also aimed to focus on well-known and less-known risk factors for IPA in COVID-19 patients, related to the main causes of immune suppression, both virus-mediated and iatrogenic, including treatments currently indicated for COVID-19. Lastly, possible preventive strategies aimed at reducing morbidity and mortality due to CAPA could be implemented.
Oxidative Stress Markers in Cerebrospinal Fluid of Newly Diagnosed Multiple Sclerosis Patients and Their Link to Iron Deposition and Atrophy
Authors: Burgetova Andrea , Dusek Petr , Uher Tomas , Vaneckova Manuela , Vejrazka Martin , Burgetova Romana , Horakova Dana , Srpova Barbora , Krasensky Jan , Lambert Lukas
Published: June 2022

Oxidative stress has been implied in cellular injury even in the early phases of multiple sclerosis (MS). In this study, we quantified levels of biomarkers of oxidative stress and antioxidant capacity in cerebrospinal fluid (CSF) in newly diagnosed MS patients and their associations with brain atrophy and iron deposits in the brain tissue. Consecutive treatment-naive adult MS patients (n = 103) underwent brain MRI and CSF sampling. Healthy controls (HC, n = 99) had brain MRI. CSF controls (n = 45) consisted of patients with non-neuroinflammatory conditions. 3T MR included isotropic T1 weighted (MPRAGE) and gradient echo (GRE) images that were processed to quantitative susceptibility maps. The volume and magnetic susceptibility of deep gray matter (DGM) structures were calculated. The levels of 8-hydroxy-2′-deoxyguanosine (8-OHdG), 8-iso prostaglandin F2α (8-isoPG), neutrophil gelatinase-associated lipocalin (NGAL), peroxiredoxin-2 (PRDX2), and malondialdehyde and hydroxyalkenals (MDA + HAE) were measured in CSF. Compared to controls, MS patients had lower volumes of thalamus, pulvinar, and putamen, higher susceptibility in caudate nucleus and globus pallidus, and higher levels of 8-OHdG, PRDX2, and MDA + HAE. In MS patients, the level of NGAL correlated negatively with volume and susceptibility in the dentate nucleus. The level of 8-OHdG correlated negatively with susceptibility in the caudate, putamen, and the red nucleus. The level of PRDX2 correlated negatively with the volume of the thalamus and both with volume and susceptibility of the dentate nucleus. From MRI parameters with significant differences between MS and HC groups, only caudate susceptibility and thalamic volume were significantly associated with CSF parameters. Our study shows that increased oxidative stress in CSF detected in newly diagnosed MS patients suggests its role in the pathogenesis of MS.
Multidimensional Approach of Heart Failure Diagnosis and Prognostication Utilizing Cardiac Imaging with Biomarkers
Authors: Kim In-Cheol , Yoo Byung-Su
Published: June 2022

Heart failure (HF) is a clinical syndrome caused by various etiologies that results in systolic and diastolic cardiac dysfunction with congestion. While evaluating HF and planning for treatment, physicians utilize various laboratory tests, including electrocardiography, diverse imaging tests, exercise testing, invasive hemodynamic evaluation, or endomyocardial biopsy. Among these, cardiac imaging modalities and biomarkers are the mainstays during HF diagnosis and treatment. Recent developments in non-invasive imaging modalities, such as echocardiography, computed tomography, magnetic resonance imaging, and nuclear imaging, have helped us understand the etiology, pathophysiology, and hemodynamics of HF, and determine treatment options and predict the outcomes. Due to the convenience of their use and potential impact on HF management, biomarkers are increasingly adopted in our clinical practice as well as research purpose. Natriuretic peptide is the most widely used biomarker for the diagnosis of HF, evaluation of treatment response, and prediction of future outcomes. Other cardiac biomarkers to evaluate the pathophysiological mechanisms of HF include myocardial injury, oxidative stress, inflammation, fibrosis, hypertrophy, and neurohormonal activation. Because HF results from complex cardiac disorders, it is essential to assess the disease status multidimensionally. The proper utilization of multimodality imaging and cardiac biomarkers can improve the quality of patient management and predict clinical outcomes in HF in the era of personalized medicine.
Study of the Anatomical Association between Morton’s Neuroma and the Space Inferior to the Deep Transverse Metatarsal Ligament Using Ultrasound
Authors: del Mar Ruiz-Herrera María , Criado-Álvarez Juan José , Suarez-Ortiz Mario , Konschake Marko , Moroni Simone , Marcos-Tejedor Félix
Published: June 2022

Morton’s neuroma (MN) is a common condition in clinical practice. The compressive etiology is the most accepted, in which compression occurs in the tunnel formed by the adjacent metatarsals, the deep transverse metatarsal ligament (DTML) and the plantar skin. Ultrasound (US) is a reliable method of study. The presence of insufficient space under the DTML may be related to the appearance of MN. Objectives: To verify the relationship between MN and the space under the DTML between the metatarsal heads of the third (M3) and the fourth (M4) metatarsals using US. Methods: This is a cross-sectional epidemiological study. The research study using the ultrasound (US) technique was carried out on 200 feet belonging to 100 patients aged 18 to 65 of both sexes, with a control group formed by 62 patients and a study group formed by 38 patients diagnosed with MN. Results: The presence of MN and the factors associated with it were studied in 100 patients using ultrasound (US). The assessment and comparison with US of the space inferior to the DTML between M3 and M4 in control groups and patients with MN show that patients with MN have a smaller size in the variable “h” (height or distance DTML-plantar skin), in the variable “b” (base or intermetatarsal distance M3 and M4) and in the variable “s” (surface of the parallelogram “h” × “b”). The predictors of MN are a decrease in dimension “b” and an increase in weight. Sitting in an office chair and the use of a bicycle, due to equinus, have an influence on the space below the DTML, reducing it and promoting the appearance of MN. Conclusions: The two US measurements (“h” and “b”) in the space below the DTML are smaller in patients with MN than in the asymptomatic group. A shorter distance between M3 and M4, and an increase in BMI are predictors of MN.
Assessment and Intervention for Tool-Use in Learning Powered Mobility Intervention: A Focus on Tyro Learners
Authors: Nilsson Lisbeth , Kenyon Lisa
Published: June 2022

Young infants, children, and persons of any age who have cognitive limitations can be thought of as tyro learners, who are beginners in learning. For tyro learners, the self-produced mobility afforded by a powered mobility device offers opportunities, to explore tool-use learning and interact with the surrounding environment, thereby potentially enhancing development and learning, providing a foundation for future goal-directed, tool-use activities. The Assessment of Learning Powered mobility use tool, version 2.0 (ALP), developed with tyro learners, is a process-based implementation package, focused on assessing and progressing an individual’s understanding of how to use a powered mobility device. Although the ALP tool can be used with any powered mobility learner, research suggests that this process-based approach may be, especially, beneficial for tyro learners, who are in the early phases of learning how to operate a powered mobility device. This article aims to (1) explain tool-use learning in powered mobility intervention; (2) distinguish between the characteristics of process-based and task-based implementation packages; (3) provide an in-depth description of using the ALP tool in providing powered mobility intervention; and (4) highlight the benefits of using the ALP tool, with a focus on tyro learners.
Transition Probability Test for an RO-Based Generator and the Relevance between the Randomness and the Number of ROs
Authors: Kodera Yuta , Sato Ryoichi , Ali Md. Arshad , Kusaka Takuya , Nogami Yasuyuki
Published: June 2022

A ring oscillator is a well-known circuit used for generating random numbers, and interested readers can find many research results concerning the evaluation of the randomness with a packaged test suit. However, the authors think there is room for evaluating the unpredictability of a sequence from another viewpoint. In this paper, the authors focus on Wold’s RO-based generator and propose a statistical test to numerically evaluate the randomness of the RO-based generator. The test adopts the state transition probabilities in a Markov process and is designed to check the uniformity of the probabilities based on hypothesis testing. As a result, it is found that the RO-based generator yields a biased output from the viewpoint of the transition probability if the number of ROs is small. More precisely, the transitions 01→01 and 11→11 happen frequently when the number l of ROs is less than or equal to 10. In this sense, l>10 is recommended for use in any application, though a packaged test suit is passed. Thus, the authors believe that the proposed test contributes to evaluating the unpredictability of a sequence when used together with available statistical test suits, such as NIST SP800-22.
Amplification, Inference, and the Manifestation of Objective Classical Information
Authors: Zwolak Michael
Published: June 2022

Our everyday reality is characterized by objective information—information that is selected and amplified by the environment that interacts with quantum systems. Many observers can accurately infer that information indirectly by making measurements on fragments of the environment. The correlations between the system, S, and a fragment, F, of the environment, E, is often quantified by the quantum mutual information, or the Holevo quantity, which bounds the classical information about S transmittable by a quantum channel F. The latter is a quantum mutual information but of a classical-quantum state where measurement has selected outcomes on S. The measurement generically reflects the influence of the remaining environment, E/F, but can also reflect hypothetical questions to deduce the structure of SF correlations. Recently, Touil et al. examined a different Holevo quantity, one from a quantum-classical state (a quantum S to a measured F). As shown here, this quantity upper bounds any accessible classical information about S in F and can yield a tighter bound than the typical Holevo quantity. When good decoherence is present—when the remaining environment, E/F, has effectively measured the pointer states of S—this accessibility bound is the accessible information. For the specific model of Touil et al., the accessible information is related to the error probability for optimal detection and, thus, has the same behavior as the quantum Chernoff bound. The latter reflects amplification and provides a universal approach, as well as a single-shot framework, to quantify records of the missing, classical information about S.
Phosphate Treatment by Five Onsite Wastewater Systems in a Nutrient Sensitive Watershed
Authors: Humphrey Charles P.
Published: June 2022

Excess phosphate (P) loading to surface waters increases productivity sometimes causing an imbalance leading to eutrophication and water quality degradation. Wastewater contains elevated concentrations of P and other contaminants that pose threats to environmental health. Onsite wastewater systems (OWS) are used in many rural areas, but most are not monitored for P removal effectiveness. The goal of this research was to gain a better understanding of the P treatment efficiency of OWS in a nutrient-sensitive watershed. Groundwater monitoring infrastructure, including networks of wells and piezometers, was installed at five sites with OWS in coastal North Carolina. Groundwater samples from the piezometers and wastewater samples from the septic tanks were collected and analyzed for phosphate and physicochemical parameters. Results suggest that significant reductions in P concentrations (79.7 to 99.1%) were occurring in the soil immediately beneath the drainfield trenches, but P concentrations in groundwater near the OWS and more than 35 downgradient were alike and significantly elevated relative to background concentrations. OWS in areas with sandy soils such as the Hoods Creek watershed may be sources of P to groundwater and surface water. Nutrient management policies in watersheds with sandy soils should include provisions for assessing and reducing P contributions from OWS to surface waters.
Can Nonwoven Tea Bags Be Used to Determine the Tea Bag Index?
Authors: Mori Taiki
Published: June 2022

Researchers have studied the impact of various anthropogenic activities on litter decomposition rates because of their large impact on the future carbon budget and climate change. However, any assessment of the global-scale impact of anthropogenic activity on litter decomposition requires standardized methods that can exclude the variability of litter chemistry. The Tea Bag Index (TBI) is widely used as a standardized method to obtain both the decomposition constant k of early-stage litter decomposition and the stabilization factor S. Recently, a tea bag manufacturer changed the materials and size of the tea bag mesh from a 0.25 mm woven mesh to a nonuniform, nonwoven mesh. To test whether these changes in mesh materials have any effect on the TBI approach, an incubation study was performed. Obtaining time series decomposition data for both green and rooibos teas, two essential assumptions of the TBI approach were examined: (i) that most of the unstabilized hydrolyzable fraction of green tea is decomposed within 90 days (unless the environment is unfavorable for decomposition) and (ii) the S of green tea is equal to that of rooibos tea. The results did not show a clear breakdown of the first assumption of the TBI approach due to the changes in mesh materials, and they did not support the second assumption. The S of rooibos tea determined by fitting an asymptote model to the time series data was significantly larger than the TBI-based S. In conclusion, the TBI may be undeterminable using nonwoven tea bags.
Efficacy of the PlasmaShield®, a Non-Thermal, Plasma-Based Air Purification Device, in Removing Airborne Microorganisms
Authors: Whiley Harriet , Keerthirathne Thilini P. , Kuhn Emma J. , Nisar Muhammad Atif , Sibley Alex , Speck Peter , Ross Kirstin E.
Published: June 2022

Airborne microorganisms play a significant role in the transmission of infectious diseases. As such, improving indoor microbial air quality can enhance infection control in numerous settings. This study examined the efficacy of the PlasmaShield® air purification device to remove airborne microorganisms under laboratory conditions. Pure cultures of model microorganisms at varying concentrations were aerosolized using a 1-jet Collison nebulizer through stainless-steel removable piping prior to reaching the PlasmaShield® device. The surviving microorganisms were captured using the Staplex® MBS-6 Six Stage Microbial Air Sampler and enumerated via culture on agar plates. The positive-hole-corrected colony/plaque-forming units were compared with the negative control (microorganisms aerosolized through an empty PlasmaShield® casing). The PlasmaShield® statistically significantly (p < 0.05) reduced airborne Escherichia coli, Staphylococcus epidermidis, Bacteriophage MS2 and Cladosporium sp. compared with the negative control. The maximum removal achieved was estimated to be 4 × log10E. coli (99.99% removal), 4 × log10S. epidermidis (99.97% removal), 7 × log10 MS2 (99.99998% removal) and 5 × log10Cladosporium sp. (99.999% removal). Scanning electron microscope images of the surviving microorganisms showed that the PlasmaShield® damaged the cell membrane of these model microorganisms. This study provides proof-of-concept evidence to support the use of this technology to improve indoor microbial air quality.
Control-Based Two-Layer Protection for Short-Circuit Fault at an LVDC Feeder Branch
Authors: Yang Jiajun , Brueske Sebastian , Buticchi Giampaolo , Gu Chunyang , Guenter Sandro , Wheeler Pat
Published: June 2022

Low-voltage dc distribution offers high efficiency for grid integration of dc-based technologies such as photovoltaic and battery storage systems and new loads such as charging stations for electric vehicles due to reduced number of conversion stages. However, the selection of protection devices, protection coordination and selectivity is still subject to research. This work proposes to use a two-layer protection technique utilizing the control capability of power converters in case of a short-circuit fault at branch level of a low voltage dc feeder. The first layer is limiting the bus current using a virtual resistance in the droop control to avoid tripping of the grid-forming converter. The second layer implements a soft fuse tripping technique for selectivity. The control concept is presented and the system stability is analyzed using impedance-based stability analysis. Experimental results on a hardware-in-the-loop setup verify the findings.
Global Maximum Power Point Tracking of Partially Shaded PV System Using Advanced Optimization Techniques
Authors: Akram Nouman , Khan Laiq , Agha Shahrukh , Hafeez Kamran
Published: June 2022

In this work, a meta-heuristic optimization based method, known as the Firefly Algorithm (FA), to achieve the maximum power point (MPP) of a solar photo-voltaic (PV) system under partial shading conditions (PSC) is investigated. The Firefly Algorithm outperforms other techniques, such as the Perturb & Observe (P&O) method, proportional integral derivative (PID, and particle swarm optimization (PSO). These results show that the Firefly Algorithm (FA) tracks the MPP accurately compared with other above mentioned techniques. The PV system performance parameters i.e., convergence and tracking speed, is improved compared to conventional MPP tracking (MPPT) algorithms. It accurately tracks the various situations that outperform other methods. The proposed method significantly increased tracking efficiency and maximized the amount of energy recovered from PV arrays. Results show that FA exhibits high tracking efficiency (>99%) and less convergence time (<0.05 s) under PSCs with less power oscillations. All of these methods have been validated in Matlab simulation software.
Assessment of Explosion Safety Status within the Area of an LNG Terminal in a Function of Selected Parameters
Authors: Kalbarczyk-Jedynak Agnieszka Magdalena , Ślączka-Wilk Magdalena , Kaup Magdalena , Ślączka Wojciech , Łozowicka Dorota
Published: June 2022

This paper examines the issues of designing optimization tasks with the objective of ensuring the safety and continuation of transportation processes. Modelling the processes that are a consequence of a breakdown is a crucial issue enabling an increase of safety at selected stages of transport. This paper elaborates on the matter of modelling hazardous situations resulting from an uncontrolled LNG release due to a crash or damage to a ship’s hull. This paper demonstrates subsequent stages of modelling along with theoretical assumptions and finally it presents the results of simulation calculations for various scenarios of LNG releases. The article shows the complexity of modelling at a time when variable atmospheric conditions occur, which hinder the planning of rescue operations in the event of an uncontrolled LNG release into the atmosphere. It needs to be remembered that making decisions in critical situations and developing proper procedures at a time when people’s lives are at risk or in the face of an environmental pollution incident constitutes one of the most significant components of effective management in transport. Two LNG release scenarios are presented in this article: catastrophic rupture and leak, for which danger zone dimensions were calculated. Simulations were conducted with the use of a tool called Phast ver. 8.23 for LNG. Calculations were made in a function of variable weather conditions and for two values of Pasquill coefficients.
A Simplified Space Vector Pulse Width Modulation Algorithm of a High-Speed Permanent Magnet Synchronous Machine Drive for a Flywheel Energy Storage System
Authors: Hu Hongjin , Wang Haoze , Liu Kun , Wei Jingbo , Shen Xiangjie
Published: June 2022

A space vector pulse width modulation (SVPWM) algorithm is an important part of the permanent magnet synchronous machine (PMSM) drive to achieve direct current (DC) to alternating current (AC) conversion. The execution of the conventional SVPWM algorithm is a complex process which will limit the sampling frequency of the high-speed PMSM drive. Low sampling frequency will cause high current total harmonic distortion (THD) and eddy current loss. To increase the sampling frequency, this paper proposes a novel simplified SVPWM algorithm. The proposed SVPWM algorithm turns the vector composition problem of the conventional SVPWM algorithm into an optimization problem of the dwell time of the basic vector. The proposed SVPWM algorithm has an optimal vector dwell time (OVDT). The dwell time of the basic vector can be directly calculated by solving the optimization problem. The proposed SVPWM algorithm does not need sector identification compared to the conventional algorithm. The experiments of the proposed SVPWM algorithm are performed in a high-speed PMSM drive of a flywheel energy storage system (FESS). Compared to the conventional SVPWM algorithm, the execution time of the proposed SVPWM algorithm is reduced by 38%. By using the proposed SVPWM algorithm, the sampling frequency can be increased from 33 kHz to 40 kHz. With the higher sampling frequency, the current THD is reduced by 25.6%. The effectiveness of the proposed simplified SVPWM algorithm is verified experimentally.
Efficiency of Emission Reduction Technologies for Residential Biomass Combustion Appliances: Electrostatic Precipitator and Catalyst
Authors: Vicente Estela D. , Duarte Márcio A. , Tarelho Luís A. C. , Alves Célia A.
Published: June 2022

Residential biomass combustion has been pointed out as one of the largest sources of atmospheric pollutants. Rising awareness of the environmental effects of residential biomass combustion emissions boosted the development of different emission reduction devices that are currently available on the market for small-scale appliances. However, detailed studies on the efficiency of these devices in different combustion systems available in Southern European countries are lacking. In this study, two pollution control devices (catalytic converter and electrostatic precipitator) were tested in two different combustion systems (batch mode operated woodstove and automatically fed pellet stove) in order to assess the emission reduction potential of the devices. Pine firewood was used to fuel the woodstove. One commercial brand of pellets and an agricultural fuel (olive pit) were taken for the experiments in the pellet stove. While the efficiency of the electrostatic precipitator in reducing PM10 was only recorded for woodstove emissions (29%), the effect of the catalyst in decreasing gaseous emissions was only visible when applied to the pellet stove flue gas. For wood pellet combustion, reductions of CO and TOC emissions were in the range of 60–62% and 74–77%, respectively. For olive pit combustion, a lower decrease of 59–60% and 64% in CO and TOC emissions, respectively, was recorded.
Risks for a Successful Transition to a Net-Zero Emissions Energy System
Authors: Malecha Ziemowit
Published: June 2022

The year 2021 brought a significant increase in CO2 emissions despite the rapid growth of new renewable energy sources (RES) installations being commissioned [...]
Achievement of Sustainable Development Goals through the Implementation of Circular Economy and Developing Regional Cooperation
Authors: Cudečka-Puriņa Natālija , Atstāja Dzintra , Koval Viktor , Purviņš Māris , Nesenenko Pavlo , Tkach Oleksandr
Published: June 2022

Circular economy is a tool based on the inclusion of environmental, social, and governance performance (ESG) in decision-making to achieve sustainable development goals (SDG). In recent years, it has become clear that business-as-usual has nothing to do with sustainability, and alternative business models, primarily on technological grounds, must be implemented to mitigate the damage caused by significant and unpredictable effects of climate change. The current situation requires unprecedented and urgent changes to policies and business development models. The current research aimed to target on industrial symbiosis as one of the business models of the circular economy. It evaluated the benefits of symbiosis and the fostering of cooperation between industries and, consequently, has a major impact on resource efficiency ratios. The research is based on quantitative and qualitative research methods, including a literature review, assessment, and application of the triangulation method. As a result of this research, the authors realized a matrix for the development of regional or cross-country industrial symbiosis that can be used by policymakers to foster the development of symbiotic interconnections on a wide scale. The authors also recommend the development of the Baltic University Program (BUP) network center of excellence and methodological justification for industries to engage in industrial symbiosis (IS).
Design of a Thermoelectric Device for Power Generation through Waste Heat Recovery from Marine Internal Combustion Engines
Authors: Konstantinou Georgios , Kyratsi Theodora , Louca Loucas S.
Published: June 2022

Modern ships discharge large amounts of energy into the environment. More specifically, internal combustion engines (ICE) of commercial and passenger ships waste significant amounts of thermal energy at high temperature through their exhaust gases that are discharged to the atmosphere. A practical approach of recovering some amount of this energy is by using thermoelectric generator systems, which can convert thermal into electrical energy, given that there is a significant temperature difference. It is the aim of this work to propose a thermoelectric generator to recover energy from the exhaust gases of marine ICEs. The proposed thermoelectric generator uses the outside surface of the ICE manifold as the hot side of the thermoelectric module, while the cold side is maintained at a low temperature through a heat sink and induced water flow. The goal of this work is to design this thermoelectric generator and identify the configuration that produces the maximum electric power. The analysis and design are performed with the use of modeling and simulation, while commercial software is employed to study the 3-dimensional coupled fluid flow and heat transfer at a steady state. A sensitivity analysis is carried out to identify the parameters with the highest influence on power production. In addition to a full factorial sensitivity analysis, the more efficient Latin hypercube sampling is used. The analysis shows that significant energy of the exhaust gases can be converted into electric power with the use of an optimized heatsink, which creates the highest temperature difference between the two sides of the thermoelectric module.
Life Cycle Saving Analysis of an Earth-Coupled Building without and with Roof Evaporative Cooling for Energy Efficient Potato Storage Application
Authors: Singh Ramkishore , Buddhi Dharam , Vatin Nikolai Ivanovich , Prakash Chander , Dixit Saurav , Khera Gurbir Singh , Solovev Sergei A. , Ilyashenko Svetlana B. , John Vinod
Published: June 2022

Preservation of potatoes in a controlled cool environment (i.e., in cold storage) consumes a substantial amount of energy. The specific energy consumption in Indian cold storage has been estimated to be between 9 and 26 kWh/ton/year. In this article, the potential for minimizing the energy consumption in the refrigeration process of cold storage through passive cooling concepts (i.e., roof evaporative cooling and the earth integration of the storage building) was explored. These passive concepts of cooling have shown significant potential for lowering the cooling loads and the energy consumption in different types of buildings. Therefore, a feasibility analysis for a potato storage building, considering the effect of the passive cooling concepts, was conducted for three different climatic conditions (i.e., hot–dry, warm–humid, and composite) in India. The energy saving potentials in the cold storage were assessed by quantifying the thermal energy exchange between the indoor and outdoor environments using the modified admittance method. The effect of heat transfer through the building envelope on total energy consumption was estimated for the building having various sunken volumes (buried depths) without and with roof evaporative cooling. Further, the economic feasibility of adopting passive concepts was assessed in terms of life cycle saving compared to the base case. Results indicate that earth coupling without and with evaporative cooling has substantial potential to reduce the cooling load and can produce significant savings.
A Simplified Techno-Economic Analysis for Sophorolipid Production in a Solid-State Fermentation Process
Authors: Martínez María , Rodríguez Alejandra , Gea Teresa , Font Xavier
Published: June 2022

Sophorolipids (SLs) are microbial biosurfactants with an important role in industry and a continuously growing market. This research addresses the use of sustainable resources as feedstock for bioproducts. Winterization oil cake (WOC) and molasses are suitable substrates for SLs via solid-state fermentation (SSF). The model proposed herein was established for annually processing 750 t of WOC and comparing three support materials: wheat straw (WS), rice husk (RH), and coconut fiber (CF). Production capacity ranged 325–414 t of SLs per year. Unit Production Cost was 5.1, 5.7, and 6.9 USD/kg SL for WS, RH, and CF production models, respectively, and was slightly lower with other substrates. Financial parameters were CAPEX 6.7 MM USD and OPEX 1.9 MM USD/y, with a NPV, IRR and payback time of 6.4 MM USD, 31% and 3.2 y, respectively. SLs recovery from the solid matrix was the major contributor to operating costs, while fermentation equipment shaped capital costs. Results show that the physical properties (bulk density, WHC) of substrates and supports define process costs beyond substrate purchase costs and process yields in SSF systems. To our knowledge, this is the first attempt to model SLs production via SSF at full scale for the economic valuation of the SSF process.
Effects of n-Heptane/Methane Blended Fuel on Ignition Delay Time in Pre-Mixed Compressed Combustion
Authors: Yoon Myeongsu , Choi Minsung , Kang Kijoong , Oh Chaeho , Park Yeseul , Choi Gyungmin
Published: June 2022

This study analyzed factors that influence the ignition delay characteristics of n-heptane/methane-blended fuel. The effects of chemical species, exhaust gas recirculation rate, compression ratio, cool/hot flames, and combustion chamber conditions (temperature, pressure, and O2 concentration) were determined and analyzed using CHEMKIN Pro. The experiment conditions for verification were 550–1000 K at 15 bar with 50% H2/50% CH4 fuel. The main combustion reactions were confirmed through reactivity analysis and sensitivity analysis on the ignition delay time. The ignition delay time at 14.7% O2 concentration was significantly higher than that at 21% O2 concentration by more than 30%. In addition, a higher ratio of methane in the blended fuel increased the ignition delay time as a result of methane dehydrogenation, delaying the ignition of heptane.
The Research on Characteristics of CI Engine Supplied with Biodiesels from Brown and Yellow Grease
Authors: Ciesielski Radosław , Zakrzewski Mateusz , Shtyka Oleksandr , Maniecki Tomasz , Rylski Adam , Wozniak Marek , Kubiak Przemyslaw , Siczek Krzysztof
Published: June 2022

The effect of three kinds of fuels used to supply a diesel engine on its characteristics, fuel consumption, and emissions was studied. The fuels comprised pure diesel, a blend of diesel with 6% of methyl ester of yellow grease in the form of rapeseed oil, and a blend of diesel with methyl ester of brown grease in the form of goose fat. The chromatographic analysis was conducted for these fuels, and the results are presented. Two tests, comprising measurement of fuel consumption and engine emissions, were conducted on a vehicle with a diesel engine operating under zero load and under full load. The engine’s characteristics, including both power and torque versus speed, were determined under full engine load. The results of these tests are presented in this paper. The results indicated that the use of different methyl ester-based biodiesel blends with the same content of diesel to supply the diesel engine resulted in different fuel consumption and emissions of the engine not only in comparison to the supply of pure diesel but between biodiesels analyzed.
Isolation and Characterization of Chicken Serum Albumin (Hen Egg Alpha-Livetin, Gal d 5)
Authors: Jiang Xingyi , Mu Han , Hsieh Yun-Hwa Peggy , Rao Qinchun
Published: June 2022

Chicken serum albumin, i.e., hen egg alpha-livetin, is a recognized food allergen in chicken meat and hen eggs. Currently, there is no immunoassay available for its detection from food matrices. The characterization of chicken serum albumin-specific antibodies and the extraction of the target protein are essential for immunoassay development. One monoclonal antibody (mAb), 3H4, was used in this study due to its selectivity to a linear epitope on avian serum albumin. To study the extraction of chicken serum albumin, phosphate-buffered saline (PBS) with two additives, i.e., sodium dodecyl sulfate (SDS) and dithiothreitol (DTT), was used for its extraction from chicken blood plasma and hen egg yolk. SDS and DTT improved the chicken serum albumin’s recovery and enhanced chicken serum albumin’s immunodetection. In addition, chicken serum albumin retained the best solubility and immunoreactivity after heat treatment in a neutral condition. It experienced degradation and aggregation in acidic and alkaline conditions, respectively. Overall, PBS containing 0.1% SDS and 1 mM DTT (pH 7.2) was a better extraction buffer for chicken serum albumin. However, the complexity of the food matrix and elevated temperature could reduce its solubility and immunoreactivity.
Hermite–Hadamard-Type Inequalities for h-Convex Functions Involving New Fractional Integral Operators with Exponential Kernel
Authors: Wu Yaoqun
Published: June 2022

In this paper, we use two new fractional integral operators with exponential kernel about the midpoint of the interval to construct some Hermite–Hadamard type fractional integral inequalities for h-convex functions. Taking two integral identities about the first and second derivatives of the function as auxiliary functions, the main results are obtained by using the properties of h-convexity and the module. In order to illustrate the application of the results, we propose four examples and plot function images to intuitively present the meaning of the inequalities in the main results, and we verify the correctness of the conclusion. This study further expands the generalization of Hermite–Hadamard-type inequalities and provides some research references for the study of Hermite–Hadamard-type inequalities.
Study on Associating Emotions in Verbal Reactions to Facial Expressions in Dementia
Authors: Hwang SungHo , Hwang JiWon , Jeong HyeonCheol
Published: June 2022

The purpose of this study was to provide basic data on cognitive therapy and to improve social support programs for the elderly with dementia by identifying the difficulties they experienced in emotional communication by identifying how they recognized emotions in verbal reactions to facial expressions using Ekman’s photographs of facial expressions and comparing their responses with the general elderly population. There were 141 participants in this study. Data collection was conducted from 3 April 2019 to 30 June 2019 in Seoul, in the Gyeonggi-do and Gangwon-do provinces of South Korea. This study performed descriptive research in which subjects made participative decisions with their guardian through recruitment. The tools used in this study included a general characteristic questionnaire and the Ekman 6 facial expressions photographs tool, which underwent intensive validity studies. The collected data were analyzed using the R version 3.5.1 statistic computing platform. The ability of the elderly with dementia to associate verbal expressions with facial expressions differed from that of the general elderly population. The rates of correct associations of verbal expressions to facial expressions were similar across dementia grades. There was a significant difference in the proportion of correct associations between positive and negative emotions in the elderly with dementia compared to the general elderly population. In the elderly with dementia, pictures showing fear, anger, and disgust had higher wrong rates of incorrect answers than correct answers. The average score of elderly with dementia in associating verbal expressions with six facial expressions was 2.69, which was even lower when they were asked to associate verbal expressions with pictures showing facial expressions of anger or disgust. This study shows that elderly persons with dementia have difficulties identifying two negative emotions (anger, disgust) and find it much easier to identify a positive emotion of happiness represented by a smiling face. Since the ability of the elderly with dementia to interpret verbal expressions to facial expressions was different from that of the general elderly population, careful attention and consideration are needed to support and communicate emotions to the elderly with dementia.
Different Vitamin D Supplementation Strategies in the First Years of Life: A Systematic Review
Authors: Corsello Antonio , Milani Gregorio Paolo , Giannì Maria Lorella , Dipasquale Valeria , Romano Claudio , Agostoni Carlo
Published: June 2022

Vitamin D (VD) is an essential micronutrient with multiple functions for human growth, and adequate intake should be guaranteed throughout life. However, VD insufficiency is observed in infants all over the world. Low VD concentration in the breast milk of non-supplemented mothers and low compliance to VD daily supplementation are the main causes of VD insufficiency, especially in the long term. Furthermore, VD supplementation dosages are still debated and differ by country. We conducted a systematic review to compare the most recent evidence on different postnatal VD supplementation strategies, determining whether supplementation given to the mother is as effective as that administered directly to the child, and whether different dosages and administration schedules differ significantly in terms of efficacy and safety. We identified 18 randomized controlled trials (RCTs) addressing the role of infant (n = 961), maternal (n = 652) or combined infant and maternal VD supplementation (n = 260 pairs). In all studies, similar outcomes emerged in terms of efficacy and safety. According to our findings, alternative approaches of VD supplementation may be adopted, especially in cases where the adherence to daily supplementation strategies is poor. This review shows that different dosages and supplementation strategies result in similar VD sufficiency rates. Therefore, international guidelines may be revised in the future to offer multiple and different options of supplementation for specific settings and ages.