bluuebunny/crossref_metadata_2025 huggingface dataset:
Plotting the Major Proteins of Alaskapox Virus
Authors: Thomas Sunil
Published: March 2024

In an era marked by rapid environmental transformations, the viability of numerous species hinges crucially on their ability to navigate and adjust to shifting climatic conditions through migration. Yet, amidst this natural quest for survival, a consequential and often overlooked consequence emerges: the inadvertent transportation of a diverse array of parasites and pathogens across landscapes. This phenomenon poses a substantial and tangible threat to global health, particularly in the wake of recent outbreaks and pandemics fueled by zoonotic viruses, which leap from animals to humans. These viruses, originating in animals but capable of infecting humans, serve as poignant reminders of the intricate relationship between human and wildlife health, and the potential dangers of disregarding this delicate balance. In 2015, the Alaskapox virus (AKPV), classified as an Orthopoxvirus, was first identified in a woman living near Fairbanks, Alaska. The first recorded fatality attributed to AKPV infection occurred in January 2024. Current evidence suggests that AKPV primarily targets small mammals, particularly red-backed voles and shrews, as evidenced by sampling efforts in the Fairbanks North Star Borough. However, it is likely that the virus is more widespread among Alaska's small mammal populations, potentially leading to undiagnosed human infections. Additionally, domestic pets, such as cats and dogs, may also contribute to the transmission of the virus. To date, no instances of human-to-human transmission have been documented, but the lack of diagnostics and vaccines for AKPV remains a concerning gap. This paper aims to address this issue by reporting the structure and epitopes of the major proteins of AKPV. This data could serve as a foundation for the development of novel diagnostics and vaccines to combat AKPV, thereby mitigating its impact on both human and animal populations.
Garlic-specific Fertilizer Improves Economic and Environmental Outcomes in China
Authors: Cui Yuandong , Zhang Shuhong , Dong Xiangyang , Li Qun , Huang Yufang , Meng Xiangping , Wang Yang , Ye Youliang
Published: March 2024

Traditional methods of garlic fertilization involve large amounts of balanced fertilizer with equal proportions of N, P, and K, leading to nutrient imbalances, reduced yield and nutritional quality, and elevated risk of environmental pollution. This study for the first time measured garlic nutrient absorption and mineral elements status in garlic fields. In addition, a garlic-specific fertilizer formula and recommended rate were designed and applied in multiple garlic fields during the 2019–21 growing season. We assessed the performance of garlic-specific fertilizer in terms of yield, quality, and nutrient utilization efficiency. We showed that garlic prefers to absorb N and K, and its absorption of P was much lower. Deficiencies in Cl, Mn, S, and Fe are found in 98.7%, 56.1%, 22.8%, and 11.9% of garlic fields. Compared with farmer fertilization, the garlic-specific fertilizers increased sprout yield by 12.9% to 30.5%, bulb yield by 11.0% to 33.5%, and net income by 18.2% to 45.6%. Furthermore, it improved the nutritional quality [vitamin C (Vc), soluble sugar (SS), and soluble protein] of the garlic and reduced the accumulation of nitrate. The formula of special fertilizer was more in line with the law of garlic nutrient absorption, increasing the nutrient utilization effect, reducing the environmental risks. Application of specific fertilizer increased N, P, and K partial productivity by 26.6% to 50.1%, 82.6% to 116.5%, and 54.6% to 83.3%, respectively. These results suggest that replacing balanced fertilizers in the garlic market with garlic-specific fertilizers can improve garlic farmers' incomes and soil health.
Rearticulating Islamic Feminism
Authors: Kabir Gedong Maulana
Published: March 2024

This article explores the role and impact of the Indonesian Women Ulema Congress—Kongres Ulama Perempuan Indonesia (KUPI) in shaping the narrative of Islamic feminism and public policy regarding gender issues in Indonesia. This movement faces challenges from both cultural (patriarchal culture) and conservative religious views that reject the narrative of Islamic feminism. Nevertheless, the two occurrences of KUPI in 2017 and 2022 demonstrate that the impact of this movement is significant. This research uses content analysis methods to assess various types of publication material, including justice gender fatwas and official publications related to KUPI. The main research question is to what extent the theological and juridical approaches KUPI used in formulating gender fatwas influence public perceptions and policies in Indonesia. This article finds that the gender justice fatwa by KUPI not only impacts the social and cultural aspects but also shapes policy decisions, particularly in areas of anti-sexual violence, forced marriage, environmental, health, and religious violence. This article enriches the academic understanding of how Islamic feminism is articulated and implemented in a context with broad cultural and religious diversity and provides new insights into the dynamics of Islamic feminism at the global level through a contemporary case study in Indonesia.
Gender Justice: Construction of Family Guidance and Counseling by the Islamic Religious Extension Communication Forum
Authors: Aibak Kutbuddin , Musonnif Ahmad
Published: March 2024

This paper aims to look at the construction of gender equality in family guidance and counselling. The construction of gender equality in the family aims as a preventive measure against family problems. This is a pattern and strategy to respond to various family problems caused by gender inequality, such as domestic violence. Through this problem, the Islamic Religious Extension Communication Forum (FKPAI) has a gender equality-based family guidance and counselling curriculum. In order to see the pattern and construction of gender equality in family guidance and counselling by FKPAI, this paper uses a qualitative method through a case study presented through descriptive techniques and content analysis as a data analysis method. The findings in this paper show that the pattern of guidance and counselling of FKPAI of the Ministry of Religious Affairs of Tulungagung and Trenggalek Regency prioritises the approach aspect. The construction of gender equality in marriage guidance and counselling by FKPAI is based on the fact that gender equality has been able to become a preventive aspect of family problems.
The Changing Role of Gender in Contemporary Muslim Families
Authors: Karimullah Suud Sarim , Ruchiat Nugraha Aat , Andini Yokke , Shofiyatun Nisa’ Ihda
Published: March 2024

In the modern era, gender roles in Muslim families have undergone a striking transformation, giving rise to exciting new dynamics in a society previously dominated by tradition. This study explores these changes using literature study methods through integrative and comprehensive literature analysis in collecting, evaluating, and integrating findings from previous studies that are relevant to the topic of study. The study's results stated that the change in gender roles in Muslim families today reflects social, cultural, and religious evolution. This brings balance and inclusiveness between men and women regarding family responsibilities and individual aspirations. Religious influences, especially in Islam, provide a framework that supports diverse interpretations of gender roles. Despite challenges and resistance, especially from groups that held traditional values, these changes increased family well-being, political participation, and economic growth. Greater gender equality in Muslim societies requires education, awareness, and mutual support. With commitment, these changes can lead Muslim communities towards inclusivity, gender justice, and benefits for all members.
A Novel Gene Signature based on Immune Cell Infiltration Landscape Predicts Prognosis in Lung Adenocarcinoma Patients
Authors: Ma Chao
Published: March 2024

Background:

The tumor microenvironment (TME) is created by the tumor
and dominated by tumor-induced interactions. Long-term survival of lung adenocarcinoma
(LUAD) patients is strongly influenced by immune cell infiltration in TME. The current
article intends to construct a gene signature from LUAD ICI for predicting patient
outcomes.

Methods:

For the initial phase of the study, the TCGA-LUAD dataset was chosen as the
training group for dataset selection. We found two datasets named GSE72094 and
GSE68465 in the Gene Expression Omnibus (GEO) database for model validation. Unsupervised
clustering was performed on the training cohort patients using the ICI profiles.
We employed Kaplan-Meier estimators and univariate Cox proportional-hazard
models to identify prognostic differentially expressed genes in immune cell infiltration
(ICI) clusters. These prognostic genes are then used to develop a LASSO Cox model
that generates a prognostic gene signature. Validation was performed using Kaplan-Meier
estimation, Cox, and ROC analysis. Our signature and vital immune-relevant signatures
were analyzed. Finally, we performed gene set enrichment analysis (GSEA) and
immune infiltration analysis on our finding gene signature to further examine the functional
mechanisms and immune cellular interactions.

Results:

Our study found a sixteen-gene signature (EREG, HPGDS, TSPAN32, ACSM5,
SFTPD, SCN7A, CCR2, S100P, KLK12, MS4A1, INHA, HOXB9, CYP4B1,
SPOCK1, STAP1, and ACAP1) to be prognostic based on data from the training cohort.
This prognostic signature was certified by Kaplan-Meier, Cox proportional-hazards, and
ROC curves. 11/15 immune-relevant signatures were related to our signature. The
GSEA results indicated our gene signature strongly correlates with immune-related pathways.
Based on the immune infiltration analysis findings, it can be deduced that a significant
portion of the prognostic significance of the signature can be attributed to resting
mast cells.

Conclusions:

We used bioinformatics to determine a new, robust sixteen-gene signature.
We also found that this signature's prognostic ability was closely related to the resting
mast cell infiltration of LUAD patients.
The Relationship between Quantitative Parameters of Dual-energy CT and
HIF-1α Expression in Non-Small Cell Lung Cancer
Authors: Meng Xi-Wen , Pi Ya-Wen , Wang Guang-Li , Qi Shu-Na , Zhang Gui-Hui , Cheng Yu-Xia
Published: March 2024

Objective::

This study aimed to investigate whether there is a correlation between quantitative parameters of dual-energy computed tomography (DECT) and
the relative expression of HIF-1α in patients with non-small cell lung cancer (NSCLC) to preliminarily explore the value of DECT in evaluating
the hypoxia of tumor microenvironment and tumor biological behavior and provide more information for the treatment of NSCLC.

Methods::

This retrospective research included 36 patients with pathologically confirmed NSCLC who underwent dual-energy enhanced CT scans. The
quantitative parameters of DECT were analyzed, including iodine concentration, water concentration, the CT values corresponding to 40keV,
70keV, 100keV, and 130keV in arterial and venous phases, and the normalized iodine concentration and the slope of the energy spectrum curve
were calculated. Postoperative specimens underwent HIF immunohistochemical staining by two pathologists. Spearman correlation analysis was
adopted as the statistical methodology. The data were analyzed by SPSS26.0 statistical software.

Results::

Water concentration (r=0.659, P<0.001 and r= 0.632, P<0.001, the CT values corresponding to 100keV (r=0.645, P<0.001 and r= 0.566, P<0.001)
and 130keV (r=0.687, P<0.001 and r= 0.682, P<0.001) in arterial and venous phases, and CT value of 70keV in arterial phase (r=0.457, P=0.005)
were positively correlated with HIF-1α expression level. There was no correlation among iodine concentration, standardized iodine concentration,
CT value of 40keV, λHU, and HIF-1α expression in arterial and venous levels (P >0.05).

Conclusion::

The quantitative parameters of DECT have a certain correlation with HIF-1α expression in NSCLC. Moreover, it has been demonstrated that
DECT can be used to predict hypoxia in tumor tissues and the prognosis of lung cancer patients.
Analysis of Suicide-related Tweets During the COVID-19 Pandemic
Authors: Balasooriya K.D.S. , Rupasingha R.A.H.M. , Kumara B.T.G.S.
Published: March 2024

Background:

The COVID-19 virus started in 2019 and badly affected the different sectors
of many countries around the world. Based on this, financial difficulties, loss of loved ones, sudden
anger, relationships, family disputes, and psychological distress increased, and individuals were
stalled from carrying out their lifestyle in a normal way, and some individuals were even motivated
to commit suicide.

Objective:

It is important to reduce the number of suicides and identify the reasons for this situation.
Through this research, the focus is on identifying the main topics discussed relevant to suicides during
the COVID-19 pandemic.

Methods:

Individuals use Twitter, a social media platform, to share their ideas freely and publically.
We collected 9750 primary data through Twitter API (Application Programming Interface). After
preprocessing and feature extraction by TF-IDF (Term Frequency-Inverse Document Frequency), we
applied the LDA (Latent Dirichlet Allocation) and Probabilistic Latent Semantic Analysis (PLSA)
topic modeling algorithms to identify topics.

Results:

Based on the LDA results, we extracted ten different topics under the three themes, such as
the impact of COVID-19, human feelings, getting support, and having awareness. Intertopic Distance
Map, Most Salient Terms, and Word Clouds Visualization are used to check the results. The coherence
score and perplexing value are used to measure how interpretable the extracted topics are to
humans. PLSA also extracted 25 topics with their probabilities, and Kullback–Leibler (KL) divergence
was used to check the results.

Conclusion:

We were able to gain insight into human emotions and the main motivations behind
suicide attempts using the topics we extracted. Expert feedback proved that LDA results were better
than PLSA. Based on that, we found the main impact of COVID-19 on human lives, how human
feelings were changed positively and negatively during that period, what supporting and awareness
methods people used, and what they preferred. The required measures can then be taken by those
responsible authorities and individuals to prevent, reduce, and get ready for this kind of suicidal incident
in the future.
Oxidative Stress and Protein Misfolding in Skin Aging
Authors: Oak Tushar , Patel Riya , Kumar Maushmi S.
Published: March 2024

Aging is a visible indicator of malfunctioning or toxic proteins that sensitize
other proteins to oxidative damage which is most prominently observed on the skin.
Protein misfolding is caused by the protein following an incorrect folding pathway
which may lead to spontaneous misfolding while oxidative stress refers to the
disruption of the balance between antioxidant defenses and reactive oxygen species
production. Oxidation may alter noncovalent interactions within proteins, peptide chain
fragmentation, and protein cross-linking, which causes protein misfolding and further
skin aging. A feedback loop is observed in all three processes. A proper understanding
of these events is significant in the formulation of anti-aging preparations and further
understanding of the mechanism of aging. In this Chapter, we will be discussing some
natural antioxidants available to combat oxidative stress which facilitate healthy aging
and normal functioning of the body. We will be elaborating on the body’s natural
defense mechanism against these problems such as the role of Chaperones. We will be
looking at the detailed mechanism of oxidative stress, protein misfolding, and their
correlation with skin aging along with factors influencing it. The biomarkers for
oxidative stress will be enlisted. A brief correlation between these processes in a test
worm and how it correlates to humans and its importance will be explained in this
chapter.
Pathogenesis of Atherosclerosis and Coronary Heart Disease: Epidemiology, Diagnostic Biomarkers and Prevention by Nutraceuticals, Functional Foods, and Plant-Derived Therapies
Authors: Kaur Prabhnain , Dahiya Ritu , Kaur Ginpreet , Buttar Harpal S. , Wilson Douglas W. , Telessy Istvan G.
Published: March 2024

Atherosclerosis is characterized by hardening/narrowing of arteries and
reduction of blood flow to vital organs. Animal models and human research show that
endothelial dysfunction and plaque development precede the pathogenesis of
atherosclerosis, and related coronary heart disease, neurological, and renal disorders.
Cardiac CT-scans are used to detect atherosclerosis. Early diagnosis of atherosclerosis
reduces mortality, morbidity, and healthcare expenditures. Biomarkers like C-reactive
protein, IL-6, IL-8, phospholipase A2, cardiac troponin, MicroRNA, miR-21, and other
endothelial inflammation biomarkers are novel targets for monitoring atherosclerosisrelated cardiovascular disorders. Anti-platelet and anti-cholesterol drugs are used in the
treatment of atherogenesis and blood vessel clots. However, cholesterol-lowering drugs

may cause serious adverse effects. Thus, safe and cost-effective non-pharmacological
anti-atherogenic and anticoagulant therapies are urgently needed. Nutraceuticals,
functional foods, plant-derived therapies, antioxidant/anti-inflammation,
foods/fruits/vegetables, and lifestyle changes (e.g., physical activity, less alcohol,
smoking cessation) reduce atherogenesis, diabetes mellitus, obesity, hypertension, LDL, and C-reactive protein in all age groups, especially younger people.
Overwhelming evidence suggests that regular physical activity (30 min/day), cessation
of cigarette smoking, and consumption of antioxidant nutraceuticals rich in flavonoids
and retinoids, fresh vegetables and fruits, omega-3 PUFA, culinary spices, probiotics,
Mediterranean-type diet, and “DASH DIET” lower the risk of atherogenesis and
cardiovascular diseases. This review summarizes current advances in the diagnosis and
management of atherosclerosis and related cardiovascular illnesses with plant-based
and wholesome diets, including the Mediterranean diet, DASH DIET, and lifestyle
changes. New preventative measures and alternative therapies, including dietary
interventions and plant-based foods may be the most cost-effective ways to manage
atherosclerosis and cardiovascular illnesses.
Pengaruh Penambahan Ekstrak Maserasi Kulit Bawang Putih pada Ransum Itik Magelang Terhadap Kadar Kolesterol, Warna, dan Bobot Kuning Telur
Authors: Hendrawan  , Anastasia Putri Setyawati  , Muhammad Akbar Firmansyah  , Nur Sofiatul Zuhriah  , Tri Puji Rahayu
Published: March 2024

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstak kulit bawang putih yang sudah dimaserasi pada ransum itik Magelang terhadap warna yolk, bobot yolk, dan kadar kolestrol yolk. Pembuatan ekstrak meliputi maserasi kulit bawang putih metode maserasi dengan pelarut etanol 96% sdengan perbandingan 1000 gram:7,5 liter (1:7,5) selama 3x24 jam, setelah itu dilakukan penguapan menggunakan rotary evaporator setelah pelarut tidak menetes dilanjutkan pemekatan dengan waterbath hingga diperoleh ekstrak. Penelitian ini dilakukan secara in vivo selama 28 hari menggunakan 40 ekor bebek betina berumur 20 minggu yang sudah bertelur. Pemeliharaan empat perlakuan dan masing-masing 5 ulangan yaitu P0= sebagai kontrol tanpa tambahan ekstrak kulit bawang; P1= 98% ransum basal + 2% ekstrak bawang putih; P2= 96% ransum basal + 4% ekstrak bawang putih; P3= 94% ransum basal + 6% ekstrak bawang putih. Hasil yang diperoleh penambahan ekstrak kulit bawang putih tidak berpengaruh nyata menurunkan kadar kolestrol pada minggu ke-3 dan ke-4. Warna yolk berpengaruh nyata antar perlakuan dengan perlakuan kontrol didapatkan hasil bahwa perlakuan kontrol memiliki warna tergelap, sedangkan pada bobot yolk tidak berpengaruh nyata.
Bobot Karkas dan Persentase Organ Itik Magelang Jantan (Anas Platyrhynchos) yang Diberi Suplemen Inulin Pada Ransumnya
Authors: Lilis Hartati  , Galy Hardyta  , Tri Puji Lestari  , Rizki Nur Amin
Published: March 2024

Itik Magelang merupakan salah satu jenis unggas dwiguna yang mampu menghasilkan daging dan telur. Optimalisasi produktivitas itik dapat dilakukan dengan memberikan imbuhan pakan (feed aditif) berupa prebiotik. Penelitian ini bertujuan untuk mengkaji pengaruh penambahan inulin dalam pakan terhadap bobot karkas dan persentase organ dalam Itik Magelang jantan. Rancangan percobaan pada penelitian ini adalah Rancangan Acak Lengkap (RAL). Penelitian ini menggunakan itik Magelang jantan sebanyak 100 ekor. Penelitian ini terdiri dari 4 perlakuan dengan 5 ulangan. Perlakuannya adalah: P0 (pakan control) P1(pakan + Inulin 0,5%) P2 (pakan + Inulin 1%) P3 (Pakan + Inulin 1,5%) dengan jumlah itik ulangan adalah 5 ekor. Variabel yang diamati meliputi: bobot karkas, dan persentase organ dalam (hati, jantung, ampela, dan Limpa). Analisis data menggunakan analisis ragam (ANOVA) dan data yang berbeda nyata diuji lanjut Duncan's Multiple Range (DMRT). Hasil penelitian ini menunjukkan bahwa penambahan inulin pada pakan tidak berpengaruh nyata terhadap bobot karkas dan persentase organ dalam. Bobot karkas (899,35 ± 92,39) persentase jantung (0,87 ± 0,52%) persentase hati (2,70 ± 0,35%) persentase ampela (4,36 ± 0,47%) persentase limpa (0,11 ± 0,05%) yang masih ke dalam kondisi normal. Berdasarkan hasil penelitian dapat disimpulkan bahwa penambahan prebiotik inulin sebanyak 0, 0,5, 1, dan 1,5% dalam pakan itik Magelang jantan tidak berpengaruh nyata terhadap bobot karkas dan persentase organ dalam (jantung, hati, ampela, dan limpa).
Transformasi Silase: Profil Terbaru Rumput Odot (Pennisetum purpureum cv Mott) Dan Dedak Padi Dengan Penggunaan Sirup Afkir
Authors: Sadarman Sadarman , Juliantoni Jepri , Febrina Dewi , Bayu Prastyo Agustin , Fazly Mhd , Qomariyah Novia
Published: March 2024

Penelitian ini bertujuan untuk mengevaluasi pengaruh penggunaan sirup komersial afkir terhadap sifat silase yang terbuat dari campuran dedak halus dan rumput odot. Dalam percobaan ini, efektivitas metode penyimpanan pakan dinilai sebagai cara untuk menjamin ketersediaan pakan disaat kekeringan. Eksperimen ini menggunakan rancangan acak lengkap dengan lima perlakuan dan lima ulangan. Intervensi yang disediakan antara lain: P1 (kontrol), berupa rumput odot dan dedak padi 5% dari bahan kering (BK), ditambah sirup afkir masing-masing sebanyak 2,50%, 5%, 7,50%, dan 10% DM pada P2, P3, P4, dan P5. Setelah itu, campuran didiamkan selama 30 hari pada suhu kamar. Unsur-unsur yang diamati adalah kandungan nutrien, suhu, pertumbuhan kapang, aroma, tekstur, dan warna silase. Berdasarkan data analisis, suhu, tekstur, dan aroma silase terbukti nyata (P<0,05) dipengaruhi oleh penambahan sirup afkir pada konsentrasi tertentu. Meskipun suhu silase tidak berbeda secara signifikan antara perlakuan, penggunaan sirup afkir pada konsentrasi 2,50-10% BK dapat meningkatkan kualitas nutrisi dan sifat fisik silase secara keseluruhan. Perlakuan terbaik terlihat pada penambahan 5% sirup afkir (P3) yang menghasilkan silase dengan nilai nutrisi dan karakteristik fisik yang optimal. Oleh karena itu, pemanfaatan sirup komersial afkir dapat menjadi alternatif yang efektif dalam meningkatkan kualitas silase dari campuran rumput odot dan dedak padi halus.
Kartini in two lenses: The shifting image of Indonesian modern woman in R.A. Kartini (1982) and Kartini (2017)
Authors: Chusna Aidatul , Utami Shofi Mahmudah Budi , Subuhi Moh. Imam
Published: March 2024

This paper aims to examine the construction of Kartini figure in two Indonesian films titled R.A. Kartini (1982) and Kartini (2017) and how it represents the idealization of Indonesian woman in both eras. By utilizing textual analysis, the study finds different images of Kartini presented in the films. The 1982 film tends to emphasize on the critical nature of Kartini and her anti-colonial attitude. Moreover, Kartini is also presented as a figure of Javanese woman who is characterized by her feminine gestures and manner. Meanwhile, the 2017 film constructs Kartini figure differently. Instead of focusing on her femininity, the film constructs Kartini as an energetic, and rebellious young woman. The different characterizations of Kartini presented in the films indicate the shifting image of an idealized woman in both eras. As the first film produced in 1982, the ideal woman is represented as a feminine and motherly figure. Meanwhile in the second film, Kartini is imagined as the representation of the female millennial generation, characterized by their productivity, and creativity.
Enhancing the Professional Caring Behaviour of Nurses: Module Development Protocol
Authors: Seman Nordianna , Mohd Shafie Zainab , Ahmad Sharoni Siti Khuzaimah , Inggriane Puspita Dewi
Published: March 2024

Positive patient outcomes are greatly enhanced by compassionate nursing care. This study protocol describes the development of a caring module by adopting the ADDIE instructional model to address identified gaps and promote caring behaviour among nurses. The module will be designed in three phases with mixed-method design and purposive sampling that includes nurses, care recipients, practitioners, and experts from comparable centres to ensure the content's relevance and effectiveness. By addressing obstacles to caring behaviour, the module has the potential to be an invaluable tool for nursing professionals' professional growth, contribute to positive patient outcomes, and promote high-quality care delivery.
Online Food Delivery Practices and Association with Body Mass Index among University Students
Authors: Ab Hamid Mohd Ramadan , Mat Rani Jannat , Khairul Anuar Syaza Firzanah , Silvi Lailatul Mahfida
Published: March 2024

This study aims to investigate the utilisation of online food delivery among 150 undergraduate students. 71.3% of participants used the online food delivery (OFD) services. Fast food was the top type of meal bought online. Participants pay more attention to the price of the food than the nutritional value. Participants perceived unhealthy foods online because they were high in salt, sugar and oil. A Pearson chi-square test revealed a statistically significant association between body mass index and OFD. In conclusion, the present study shows that participants place less emphasis on the nutritional value of food when ordering online.
Diagnosing the Well-Being of Gig Workers in Malaysia: A Viable System Model Approach
Authors: Abd Samad Khairunnisa , Anuar Muhammad Eddy Aizad , Abd Rahman Nur Hayati , Ahmad Khaizie Sazimah , Harmain Hendra , Satrianto Alpon , Mahadi Nur Farhah
Published: March 2024

This paper aims to assess the well-being of gig workers in Malaysia using the Viable System Model (VSM) approach. The qualitative methodology is employed through semi-structured online interviews with two gig workers and a focus group discussion with policymakers. The current gig system adheres to the five tenets of VSM, signifying the interconnection between policymakers. This represents the strength of VSM in emphasising the importance of flexibility and adaptability in complex systems. The emergent issues significantly call for government and policymakers to design the right policies to enhance the welfare of gig workers overall.
Knowledge Map on Construction of Ceramic Tableware Design
Authors: Wu Wenchao , Irwan Syah Md Yusoff  , Hassan bin Hj Alli  , Wang Heng
Published: March 2024

The research analyzed 347 ceramic tableware design papers published in the CNKI database from 2003 to 2023 through CiteSpace, revealing the hotspots and future trends of ceramic tableware design research in the past 20 years. The study employs descriptive statistical analysis, keyword mapping, and burst detection to emphasize the critical role of metrics in future research. The graphical quantification reveals the research trends in ceramic tableware design, identifies the research gaps, challenges, and opportunities, and provides a firm reference and new ideas for future research.
Current Review on Issues and Challenges for the Immovable Property Auction Process In Malaysia
Authors: Shaari Norshafiqah , Sulaiman Muhammad Azwan , Alias Muhammad Nazim , Lestari Nadia Ayu Rahma
Published: March 2024

The immovable property public auction process is a legal mechanism used to revoke the rights of original owners who have violated a contract. Banks will sell distressed property when a borrower fails to repay their housing loan. There is a significant knowledge gap in understanding Malaysia's immovable property auction processes. This research aims to address this gap by reviewing existing literature, gathering secondary data, and addressing the need for more standardization in the public auction procedure. The findings have significant benefits for stakeholders in property auctions and aim to enhance the auction process by developing standardized standards.
Learning Style and English Argumentative Writing Proficiency – How They Complement Each Other
Authors: Tian Jie , Ng Soo Boon
Published: March 2024

Argumentative writing in a foreign language is challenging for non-native speakers. The study was conducted in a China Normal University with 356 English major participators to uncover whether specific Learning Style (Converging. Diverging, Assimilating, Accommodating) has a higher significant impact on English Argumentative Writing Proficiency (EAWP). This study employed an explanatory sequential mixed-method research design. Findings showed that Convergers obtained the highest mean score in EAWP, while Divergers gained the lowest. The interviews revealed that students with different LS generally underwent four similar writing procedures. However, they differ concerning the strategies they employ in the writing process.
Rapport Building in Written Crisis Services: Qualitative Content Analysis
Authors: Schwab-Reese Laura , Short Caitlyn , Jacobs Larel , Fingerman Michelle
Published: March 2024

Background

Building therapeutic relationships and social presence are challenging in digital services and maybe even more difficult in written services. Despite these difficulties, in-person care may not be feasible or accessible in all situations.

Objective

This study aims to categorize crisis counselors’ efforts to build rapport in written conversations by using deidentified conversation transcripts from the text and chat arms of the National Child Abuse Hotline. Using these categories, we identify the common characteristics of successful conversations. We defined success as conversations where help-seekers reported the hotline was a good way to seek help and that they were a lot more hopeful, a lot more informed, a lot more prepared to address the situation, and experiencing less stress, as reported by help-seekers.

Methods

The sample consisted of transcripts from 314 purposely selected conversations from of the 1153 text and chat conversations during July 2020. Hotline users answered a preconversation survey (ie, demographics) and a postconversation survey (ie, their perceptions of the conversation). We used qualitative content analysis to process the conversations.

Results

Active listening skills, including asking questions, paraphrasing, reflecting feelings, and interpreting situations, were commonly used by counselors. Validation, unconditional positive regard, and evaluation-based language, such as praise and apologies, were also often used. Compared with less successful conversations, successful conversations tended to include fewer statements that attend to the emotional dynamics. There were qualitative differences in how the counselors applied these approaches. Generally, crisis counselors in positive conversations tended to be more specific and tailor their comments to the situation.

Conclusions

Building therapeutic relationships and social presence are essential to digital interventions involving mental health professionals. Prior research demonstrates that they can be challenging to develop in written conversations. Our work demonstrates characteristics associated with successful conversations that could be adopted in other written help-seeking interventions.
The Political Economy of Digital Health Equity: Structural Analysis
Authors: Shaw James , Glover Wiljeana
Published: March 2024

Digital technologies have produced many innovations in care delivery and enabled continuity of care for many people when in-person care was impossible. However, a growing body of research suggests that digital health can also exacerbate health inequities for those excluded from its benefits for reasons of cost, digital literacy, and structural discrimination related to characteristics such as age, race, ethnicity, and socioeconomic status. In this paper, we draw on a political economy perspective to examine structural barriers to progress in advancing digital health equity at the policy level. Considering the incentive structures and investments of powerful actors in the field, we outline how characteristics of neoliberal capitalism in Western contexts produce and sustain digital health inequities by describing 6 structural challenges to the effort to promote health equity through digital health, as follows: (1) the revenue-first incentives of technology corporations, (2) the influence of venture capital, (3) inequitable access to the internet and digital devices, (4) underinvestment in digital health literacy, (5) uncertainty about future reimbursement of digital health, and (6) justified mistrust of digital health. Building on these important challenges, we propose future immediate and long-term directions for work to support meaningful change for digital health equity.
Electronic Media Use and Sleep Quality: Updated Systematic Review and Meta-Analysis
Authors: Han Xiaoning , Zhou Enze , Liu Dong
Published: March 2024

Background

This paper explores the widely discussed relationship between electronic media use and sleep quality, indicating negative effects due to various factors. However, existing meta-analyses on the topic have some limitations.

Objective

The study aims to analyze and compare the impacts of different digital media types, such as smartphones, online games, and social media, on sleep quality.

Methods

Adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, the study performed a systematic meta-analysis of literature across multiple databases, including Web of Science, MEDLINE, PsycINFO, PubMed, Science Direct, Scopus, and Google Scholar, from January 2018 to October 2023. Two trained coders coded the study characteristics independently. The effect sizes were calculated using the correlation coefficient as a standardized measure of the relationship between electronic media use and sleep quality across studies. The Comprehensive Meta-Analysis software (version 3.0) was used to perform the meta-analysis. Statistical methods such as funnel plots were used to assess the presence of asymmetry and a p-curve test to test the p-hacking problem, which can indicate publication bias.

Results

Following a thorough screening process, the study involved 55 papers (56 items) with 41,716 participants from over 20 countries, classifying electronic media use into “general use” and “problematic use.” The meta-analysis revealed that electronic media use was significantly linked with decreased sleep quality and increased sleep problems with varying effect sizes across subgroups. A significant cultural difference was also observed in these effects. General use was associated with a significant decrease in sleep quality (P<.001). The pooled effect size was 0.28 (95% CI 0.21-0.35; k=20). Problematic use was associated with a significant increase in sleep problems (P≤.001). The pooled effect size was 0.33 (95% CI 0.28-0.38; k=36). The subgroup analysis indicated that the effect of general smartphone use and sleep problems was r=0.33 (95% CI 0.27-0.40), which was the highest among the general group. The effect of problematic internet use and sleep problems was r=0.51 (95% CI 0.43-0.59), which was the highest among the problematic groups. There were significant differences among these subgroups (general: Qbetween=14.46, P=.001; problematic: Qbetween=27.37, P<.001). The results of the meta-regression analysis using age, gender, and culture as moderators indicated that only cultural difference in the relationship between Eastern and Western culture was significant (Qbetween=6.69; P=.01). All funnel plots and p-curve analyses showed no evidence of publication and selection bias.

Conclusions

Despite some variability, the study overall confirms the correlation between increased electronic media use and poorer sleep outcomes, which is notably more significant in Eastern cultures.
Digital Alcohol Interventions Could Be Part of the Societal Response to Harmful Consumption, but We Know Little About Their Long-Term Costs and Health Outcomes (Preprint)
Authors: Ulfsdotter Gunnarsson Katarina , Henriksson Martin , Bendtsen Marcus
Published: March 2024

UNSTRUCTURED

Alcohol consumption causes both physical and psychological harm and is a leading risk factor for noncommunicable diseases. Digital alcohol interventions have been found to support those looking for help by giving them tools for change. However, whether digital interventions can help tackle the long-term societal consequences of harmful alcohol consumption in a cost-effective manner has not been adequately evaluated. In this Viewpoint, we propose that studies of digital alcohol interventions rarely evaluate the consequences of wider dissemination of the intervention under study, and that when they do, they do not take advantage of modeling techniques that allow for appropriately studying consequences over a longer time horizon than the study period when the intervention is tested. We argue that to help decision-makers to prioritize resources for research and dissemination, it is important to model long-term costs and health outcomes. Further, this type of modeling gives important insights into the context in which interventions are studied and highlights where more research is required and where sufficient evidence is available. The viewpoint therefore invites the researcher not only to reflect on which interventions to study but also how to evaluate their long-term consequences.
The Political Economy of Digital Health Equity: Structural Analysis (Preprint)
Authors: Shaw James , Glover Wiljeana
Published: March 2024

UNSTRUCTURED

Digital technologies have produced many innovations in care delivery and enabled continuity of care for many people when in-person care was impossible. However, a growing body of research suggests that digital health can also exacerbate health inequities for those excluded from its benefits for reasons of cost, digital literacy, and structural discrimination related to characteristics such as age, race, ethnicity, and socioeconomic status. In this paper, we draw on a political economy perspective to examine structural barriers to progress in advancing digital health equity at the policy level. Considering the incentive structures and investments of powerful actors in the field, we outline how characteristics of neoliberal capitalism in Western contexts produce and sustain digital health inequities by describing 6 structural challenges to the effort to promote health equity through digital health, as follows: (1) the revenue-first incentives of technology corporations, (2) the influence of venture capital, (3) inequitable access to the internet and digital devices, (4) underinvestment in digital health literacy, (5) uncertainty about future reimbursement of digital health, and (6) justified mistrust of digital health. Building on these important challenges, we propose future immediate and long-term directions for work to support meaningful change for digital health equity.
A Snapshot of COVID-19 Vaccine Discourse Related to Ethnic Minority Communities in the United Kingdom Between January and April 2022: Mixed Methods Analysis (Preprint)
Authors: Ullah Nazifa , Martin Sam , Poduval Shoba
Published: March 2024

BACKGROUND

Existing literature highlights the role of social media as a key source of information for the public during the COVID-19 pandemic and its influence on vaccination attempts. Yet there is little research exploring its role in the public discourse specifically among ethnic minority communities, who have the highest rates of vaccine hesitancy (delay or refusal of vaccination despite availability of services).

OBJECTIVE

This study aims to understand the discourse related to minority communities on social media platforms Twitter and YouTube.

METHODS

Social media data from the United Kingdom was extracted from Twitter and YouTube using the software Netlytics and YouTube Data Tools to provide a “snapshot” of the discourse between January and April 2022. A mixed method approach was used where qualitative data were contextualized into codes. Network analysis was applied to provide insight into the most frequent and weighted keywords and topics of conversations.

RESULTS

A total of 260 tweets and 156 comments from 4 YouTube videos were included in our analysis. Our data suggests that the most popular topics of conversation during the period sampled were related to communication strategies adopted during the booster vaccine rollout. These were noted to be divisive in nature and linked to wider conversations around racism and historical mistrust toward institutions.

CONCLUSIONS

Our study suggests a shift in narrative from concerns about the COVID-19 vaccine itself, toward the strategies used in vaccination implementation, in particular the targeting of ethnic minority groups through vaccination campaigns. The implications for public health communication during crisis management in a pandemic context include acknowledging wider experiences of discrimination when addressing ethnic minority communities.
Designing mHealth Apps to Incorporate Evidence-Based Techniques for Prolonging User Engagement (Preprint)
Authors: Monachelli Rebecca , Davis Sharon Watkins , Barnard Allison , Longmire Michelle , Docherty John P , Oakley-Girvan Ingrid
Published: March 2024

UNSTRUCTURED

Maintaining user engagement with mobile health (mHealth) apps can be a challenge. Previously, we developed a conceptual model to optimize patient engagement in mHealth apps by incorporating multiple evidence-based methods, including increasing health literacy, enhancing technical competence, and improving feelings about participation in clinical trials. This viewpoint aims to report on a series of exploratory mini-experiments demonstrating the feasibility of testing our previously published engagement conceptual model. We collected data from 6 participants using an app that showed a series of educational videos and obtained additional data via questionnaires to illustrate and pilot the approach. The videos addressed 3 elements shown to relate to engagement in health care app use: increasing health literacy, enhancing technical competence, and improving positive feelings about participation in clinical trials. We measured changes in participants’ knowledge and feelings, collected feedback on the videos and content, made revisions based on this feedback, and conducted participant reassessments. The findings support the feasibility of an iterative approach to creating and refining engagement enhancements in mHealth apps. Systematically identifying the key evidence-based elements intended to be included in an app’s design and then systematically testing the implantation of each element separately until a satisfactory level of positive impact is achieved is feasible and should be incorporated into standard app design. While mHealth apps have shown promise, participants are more likely to drop out than to be retained. This viewpoint highlights the potential for mHealth researchers to test and refine mHealth apps using approaches to better engage users.
Enhancing Suicide Risk Prediction With Polygenic Scores in Psychiatric Emergency Settings: Prospective Study (Preprint)
Authors: Lee Younga Heather , Zhang Yingzhe , Kennedy Chris J , Mallard Travis T , Liu Zhaowen , Vu Phuong Linh , Feng Yen-Chen Anne , Ge Tian , Petukhova Maria V , Kessler Ronald C , Nock Matthew K , Smoller Jordan W
Published: March 2024

BACKGROUND

Despite growing interest in the clinical translation of polygenic risk scores (PRSs), it remains uncertain to what extent genomic information can enhance the prediction of psychiatric outcomes beyond the data collected during clinical visits alone.

OBJECTIVE

This study aimed to assess the clinical utility of incorporating PRSs into a suicide risk prediction model trained on electronic health records (EHRs) and patient-reported surveys among patients admitted to the emergency department.

METHODS

Study participants were recruited from the psychiatric emergency department at Massachusetts General Hospital. There were 333 adult patients of European ancestry who had high-quality genotype data available through their participation in the Mass General Brigham Biobank. Multiple neuropsychiatric PRSs were added to a previously validated suicide prediction model in a prospective cohort enrolled between February 4, 2015, and March 13, 2017. Data analysis was performed from July 11, 2022, to August 31, 2023. Suicide attempt was defined using diagnostic codes from longitudinal EHRs combined with 6-month follow-up surveys. The clinical risk score for suicide attempt was calculated from an ensemble model trained using an EHR-based suicide risk score and a brief survey, and it was subsequently used to define the baseline model. We generated PRSs for depression, bipolar disorder, schizophrenia, suicide attempt, and externalizing traits using a Bayesian polygenic scoring method for European ancestry participants. Model performance was evaluated using area under the receiver operator curve (AUC), area under the precision-recall curve, and positive predictive values.

RESULTS

Of the 333 patients (n=178, 53.5% male; mean age 36.8, SD 13.6 years; n=333, 100% non-Hispanic and n=324, 97.3% self-reported White), 28 (8.4%) had a suicide attempt within 6 months. Adding either the schizophrenia PRS or all PRSs to the baseline model resulted in the numerically highest discrimination (AUC 0.86, 95% CI 0.73-0.99) compared to the baseline model (AUC 0.84, 95% Cl 0.70-0.98). However, the improvement in model performance was not statistically significant.

CONCLUSIONS

In this study, incorporating genomic information into clinical prediction models for suicide attempt did not improve patient risk stratification. Larger studies that include more diverse participants are required to validate whether the inclusion of psychiatric PRSs in clinical prediction models can enhance the stratification of patients at risk of suicide attempts.