bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficacy of Wushaoshe Qufeng Tablet and leflunomide combination therapy in the management of rheumatoid arthritis, and its influence on incidence of adverse drug reactions
Authors: Xin Zenghui , Zhang Xiangwei
Published: May 2023

Purpose: To study the effectiveness and safety of combined use of Wushaoshe Qufeng tablets andleflunomide in the treatment of rheumatoid arthritis patients.Methods: A retrospective trial was conducted among 120 patients with rheumatoid arthritis hospitalized in Heyuan Hospital of Traditional Chinese Medicine, Heyuan, from February 2020 to February 2021. The patients were equally divided into study group (n = 60) and control group (n = 60). Both groups received conventional treatment. in addition, the control group received leflunomide, whereas the experimental group received Wushaoshe Qufeng tablets. The two groups were compared with respect to laboratory indicators, TCM syndrome scores, and adverse events.Results: The post-treatment TCM syndrome scores was lower in the experimental group versus control group (p < 0.001). After treatment, the study group was superior to the control group in terms of their biochemical indicators (p < 0.001). Safety profile was better in the study group than in the control group (p < 0.05). Treatment effectiveness was significantly higher in the study group than in the control group (p < 0.05).Conclusion: Combined treatment of rheumatoid arthritis patients with Wushaoshe Qufeng tablets and leflunomide shows improved biochemical indicators, mitigates clinical symptoms, and enhances treatment effectiveness. Moreover, the combination therapy is safe, and therefore, should be considered for the management of rheumatoid arthritis patients.
Treatment efficacy of carrelizumab in metastatic castration-resistant prostate cancer, and the significance of circulating tumor DNA fraction
Authors: Zhou Henan , Chen Yanning , Zhang Xiaonan , Sang Yuanyuan
Published: May 2023

Purpose: To explore the efficacy of carrelizumab in the treatment of metastatic castration-resistant prostate cancer (mCRPC), and the significance of circulating tumor DNA (ctDNA) fraction in the process.Methods: 100 mCRPC patients who were treated in the Oncology Department of Harbin Medical University Cancer Hospital in a time frame of January 2018 to January 2019 were enrolled and assigned (1:1) into control and study groups and were given a regimen consisting of a combination of docetaxel and prednisone. Prognosis of patients with high and low ctDNA fractions relative to baseline ctDNA level, was compared.Results: The study group obtained considerably higher objective response rate (ORR) in relation to the control group (p < 0.05). Serum levels of prostate-specific antigen (PSA) and testosterone (TTE) were significantly lower in the study group versus control group. Better quality of life and bladder function were witnessed in the study group when compared to control group (p < 0.05). The proportion of patients with ctDNA fraction < 2 % in the study group significantly increased, but there was no significant change in ctDNA in the control group. The clinical prognosis of patients with low ctDNA fraction was significantly better than that of patients with high fraction (p < 0.05).Conclusion: Combined use of carrelizumab and docetaxel-prednisone regimen for mCRPC patients substantially improved clinical efficacy, quality of life, and long-term prognosis, while reducing ctDNA levels. Thus, the combination regimen has promise for the treatment of mCRPC patients.
Circ_0001953 contribute to retinal vascular endothelial cell injury induced by high glucose through regulating miR 186
Authors: Yuan Yazhen , Guan Yongqing , Shao Chenjun , Wang Hui , Zhang Shuangmei
Published: May 2023

Purpose: To investigate the effects of circ_0001953/miR-186 on human retinal vascular endothelial cell (HRVEC) injury evoked by high glucose. Methods: A cell model (HG group) was established using high glucose-treated HRVECs, while untreated HRVECs were used as the control group (Con group). The levels of endothelin-1 (ET-1), ICAM-1 and IL-6 were evaluated by ELISA and the content of malondialdehyde (MDA) and superoxide dismutase (SOD) in HRVECs were determined. Apoptosis rate was tested adopting flow cytometry. The interrelationship between circ_0001953 and miR-186 was assessed using dual luciferase reporter assay. Measurement of Bax and Bcl-2 was implemented via western blot. Results: In HG group, circ_0001953 increased while miR-186 was downregulated, ET-1, IL-6, ICAM-1, and apoptosis rate increased and accompanied with up-regulated Bax content and declined Bcl-2 protein level. Furthermore, the content of MDA increased and SOD decreased. MiR-186 was a target of circ_0001953. Conclusion: Inhibition of circ_0001953 can repress inflammation, oxidative stress and apoptosis in HRVECs by up-regulating the expression of miR-186.
Monitored care during anesthesia with remifentanil and lidocaine in pediatric strabismus surgery: A single center experience
Authors: Zhu Shili , Qu Shuangquan , Wang Jiangping
Published: May 2023

Purpose: To evaluate the use of monitored anesthesia care (MAC) in pediatric strabismus surgery. Methods: A total of 17 cases undergoing strabismus surgery with MAC were included in this study. The protocol for sedation was standardized and data were collected prospectively for an ongoing quality assurance project. Intravenous channels were established in the ward for all the children, and penehyclidine 0.01 mg/kg and ondansetron 0.1 mg/kg were injected intravenously. After communicating with children the second time, 0.05 mg/kg midazolam, 0.1 μg/kg sufentanil, and 2 mg/kg propofol were injected intravenously. Continuous intravenous pumping of remifentanil 0.1 ~ 0.2 μg/kg/min while local infiltration anesthesia was performed with 1 % lidocaine after the loss of consciousness. Results: It took 7.0 ± 3.5 min to wake up successfully. There was no nausea, vomiting, or delirium after the operation. The children had good postoperative recovery and no bad memories, and they and their families were highly satisfied with the surgery.Conclusion: Local anesthesia and MAC produces satisfactory sedation in most patients without switching to general anesthesia. However, it has to be fully demonstrated that MAC local anesthesia is superior to general anesthesia in pediatric strabismus surgery via multi-centered studies.
Effect of leuprorelin plus growth hormone on serum luteinizing hormone, follicle stimulating hormone, and estradiol levels in children with idiopathic central precocious puberty
Authors: Zhao Song , Cui Yingying
Published: May 2023

Purpose: To evaluate the effects of leuprorelin plus growth hormone on serum luteinizing hormone (LH), follicle-stimulating hormone (FSH), and estradiol (E2) levels in children with idiopathic central precocious puberty. Methods: A total of 102 girls with idiopathic central precocious puberty who met the inclusion criteria between April 2020 and September 2021 were enrolled in this study, and assigned randomly to either a control group given leuprorelin only, or a combined treatment group given leuprorelin plus growth hormone. There were 51 cases in each group. The parameters/indices evaluated include sex hormone levels (serum LH, FSH, and E2), height standard deviation scores (HtSDS), predicted adult height (PAH), and insulin-like growth factors-1 (IGH-1). Results: Patients administered combined therapy showed lower levels of LH, FSH, and E2 than those on mono-therapy (p < 0.05). Leuprorelin plus growth hormone resulted in significantly higher HtSDS and PAH, and lower IGF-1 levels compared with those who received leuprorelin (p < 0.05). Conclusion: The combination of leuprorelin and growth hormone effectively reduces the serum levels of LH, FSH, and E2 in children with idiopathic central precocious puberty, and improves their linear growth rate and adult height. However, economic benefits and patient acceptance should be considered in future studies to assess its overall applicability.
Effect of different conization ranges on pregnancy outcomes
Authors: Wang Yue , Liu Shasha , Liu Jixiao , Guo Yuling , Qu Pengpeng
Published: May 2023

Purpose: To analyze the influence of different conization on pregnancy outcomes. Methods: The data of 78 women at childbearing age having cervical conization in our hospital from January 2013 till December 2015, was collected and analyzed. The control group comprised of 80 women of childbearing age with matched clinical data, who did not undergo cervical conization. Data on the conization procedure were analyzed and pregnancy and obstetric outcomes were assessed. using the. Comparisons were made using the 2test or the Fisher exact test and Student T-test as appropriate. Results: Cold knife cervical conization prolonged the time to conception in patients. Following the procedure, the incidence of premature delivery and premature rupture of membranes were significantly increased as also the rate of early abortions. The depth and circumference of conization was found to be directly correlated with the rate of premature delivery and premature membrane rupture, but not with fetal growth restriction and macrosomia. Conclusion: The depth and circumference of resection should be based on the type of cervical lesions as well as the prognosis and the future pregnancy plans of the patients.
Verwendung von Freud. Aspekte zu Weiblichkeit, männlicher Homosexualität, Kolonialismus und Heredität in der klassischen Psychoanalyse
Authors: Strutzenberger Thiemo
Published: May 2023

»Verwendung von Freud« setzt sich mit dem umstrittenen und ungeklärten Status der psychoanalytischen Klassik in feministischen, queeren und postkolonialen Studien auseinander. Die Berufung auf den unkommentierten Originaltext Freuds ist Basis für den Versuch, die Psychoanalyse differenziert und wissenshistorisch einzuordnen. Methodisch werden zeitgenössische Freudkritiken, die mitunter auf ähnliche Weise wiederholte Verdikte verhängen, mit Formulierungen Freuds abgeglichen. Anhand einer genauen Betrachtung wird beurteilt inwieweit Freuds Status als homophober oder antisemitischer Rassist mindestens berechtigt ist oder inwiefern diese Kritiken nicht vielmehr auf verkürzenden Fehllektüren beruhen. Die Studie zeigt, dass angesichts seiner paradoxen rhetorischen Strategien die Gleichsetzung des Textes mit männlich-heterosexuellen und weiß-suprematistischen Herrschaftsdiskursen aufgelöst und diese Bewertung der klassischen Psychoanalyse bei genauerer Lektüre auf den Kopf gestellt werden kann. Zudem wird deutlich, dass die feministische Theorietradition, welche auf den »Weiblichkeitsstreit« der 1920er Jahre zurück geht, in der etablierten Psychoanalyse nicht ausreichend gewürdigt worden ist. Diese Tradition hat sich zum Ziel gesetzt die durchweg problematischen und (pseudo-)analytischen Setzungen Freuds zur sexuellen Differenz grundlegend zu überwinden.
Scribble and the Structures of Depiction: Exploring relationships between patterns of children’s spontaneous gestural mark making and adult designed pictorial schemes in the context of the rectangle.
Authors:   , Parsons Jonathan
Published: May 2023

This study makes a contribution to knowledge through art practice by producing – for the first time – a meta-analysis of children’s scribble typologies and an examination of the correlations between those typologies and simple pictorial structures produced by adults in the context of the rectangle. This research is predicated on the primacy of art practice as a means of research enquiry, both in its role as a materials-based and visual means of finding things out and by using practice as a comparative method across fields and disciplines. The wider significance of this study is its contribution to the development of methodologies of Fine Art practice through research and through emphasising the underdeveloped links between artists’ image making, established cognitive and semiotic research into pictorial typologies and the graphic structures found in children’s drawings. Application of lines and marks to a rectangular surface is a typical method of pictorial construction. Picture making occurs early in human development when infants begin to scribble, usually on rectangular sheets of paper. Studies of the early developmental stages of children’s drawings have identified basic kinds of scribble pattern that evolve into more well-defined graphic forms. A meta-analysis of these typologies had never been put together before this research was undertaken. Nor had a comparison been made between typologies of scribble pattern and the pictorial structures occurring in the simplest visual communication designs produced by adults. Such a comparative study had never been used to generate a body of new artwork as research. The findings indicate that there is a finite typology of 41 Primary Line Formations that are commonly found across studies of children’s spontaneous gestural mark-making. This was compared with the simplest adult designed pictorial structures, namely heraldic partitions and alphanumeric displays. As practice-based research, this PhD demonstrates that, in the context of the rectangle, the phenomena under study are related in terms of: 1. Configural morphology and how this is perceived; 2. Modes of representation and types of abstraction; 3. Modularity.
On triviality of uniform Diophantine exponents of lattices
Authors: German Oleg N.
Published: May 2023

In this paper we prove that uniform Diophantine exponents of lattices attain
only trivial values.
PECULIARITIES OF MARKETING ACTIVITIES OF AGRARIAN ENTERPRISES IN THE CONDITIONS OF MARTIAL LAW
Authors: Lohosha Roman , Mazur Kateryna , Alieksieieva Olha , Babyna Olha , Babyn Ihor , Belkin Igor , Germaniuk Natalia , Gontaruk Yaroslav , Harbar Zhanna , Kubai Oksana , Koval Olena , Pidlubnyi Vladyslav , Trapaidze Sofiia
Published: May 2023

All rights reserved. Printed in the United States of America. No part of this publication may be reproduced, distributed, or transmitted, in any form or by any means, or stored in a data base or retrieval system, without the prior written permission of the publisher. The content and reliability of the articles are the responsibility of the authors. When using and borrowing materials reference to the publication is required.
CONCEPTUALIZATION OF STUDENT-FACULTY
RELATIONSHIPS IN HEALTH PROFESSIONS
EDUCATION: A PRELIMINARY REPORT OF A
SCOPING REVIEW
Authors: Escoto Yosef Eduardo L. , Abantao Alexandra Louise R. , Cordero Maria Mikaela Louise G. , David Bianca Marie C. , de Villa Corina Priscilla C. , Etpison Megan R. , Palomar Jaelen Kyla G. , Perez Krysta Ellieza C. , Sampan Mary Dominique P. , Santos Engeliko Edgar H.
Published: May 2023

Introduction: The aim of this study was to understand how Student-Faculty Relationships (S-FR) has been conceptualized, defined, or operationalized in Health Professions Education (HPED).
Methods: In a scoping review, the authors searched CINAHL for literature on S-FR in HPEd from the year 2002-2022. Twentynine (29) articles met the inclusion criteria. Explicit content on defining S-FR terminologies were analyzed through thematic analysis.
Results: Eight similar terminologies in the conceptualization of S-FR, namely teacher-student relationship, student-instructor relationship, caring relationship, advising, coaching, preceptorship, supervision, and mentorship, are identified. Inconsistent use of terminologies implies the lack of a universal framework for S-FR in HPEd. However, most of these terminologies similarly conceptualize S-FR as an interaction between students and faculty centering on faculty guidance and support for students to develop clinical knowledge, skills, and attitude for personal and professional development.
Discussion: This review is the first report on the conceptualization of S-FR in HPEd. While several terminologies are used in the studies, conceptualizations are found to be comparable. The context-dependency of S-FR was remarkable among literature as differences in HPEd literature are seen in terms of time frame, degree of formality, setting, and persons involved. Although this may pose a challenge in establishing a universal framework for S-FR, it may also inform researchers to consider these as variables. The results provide a baseline for conceptualizing and operationalizing S-FR in HPEd. Further research is needed to facilitate the development of a universal framework to pave the way for improved academic policies, clinical training, and communication among health professionals and researchers.
To accept or reject? Undergraduate
physical therapy students’ attitudes and factors toward COVID-19 vaccine
Authors: Justo Odette , Pacaldo Alaise , Garcillan Jane Laurice , Soliven Rina Theresa
Published: May 2023

Introduction: The transition from online to face-to-face classes in the Philippines necessitated vaccination against COVID-19 for the students to prevent its transmission. The country has yet to benefit from herd immunity given the Filipinos’ hesitancy to COVID-19 vaccine (CoVax). The objective of the study is to describe the attitude of the undergraduate physical therapy students toward CoVax and determine the correlation between attitude toward CoVax and vaccine hesitancy factors.
Methods: A descriptive-correlational research design was used. A convenience sample of 1st year college freshmen (n = 13) was used in the study. A 5-point Likert scale was used to measure attitude toward CoVax and vaccine hesitancy factors. Pearson correlation was used to determine the correlation between attitude toward CoVax and vaccine hesitancy factors and paired t test to compare change in attitude toward CoVax before and after getting vaccinated.
Results: Majority (62%) of the students expressed a neutral attitude toward CoVax before getting vaccinated. Among all factors, the students rated their confidence (4.31) with CoVax as high but were less confident (3.92) and complacent (3.31) about the vaccine. A negative attitude toward COVAX before vaccination showed a statistically significant relationship with CoVax confidence (r = -.565; n = 13; p = .004). There was a change in the attitude toward CoVax from neutral before vaccination toward acceptance after getting vaccinated; however, the change, .31, 95% CI [-.72-1.33], was not statistically significant t (12) = .652, p = 0.527.
Discussion: Reducing complacency toward and improving confidence in CoVax must be done to improve the attitude of the students toward acceptance of the CoVax.
San Agustín. Motivo para el año de la fe
Authors: Morillo Rey Pablo Antonio
Published: May 2023

Coincidiendo con los cincuenta años del inicio del Concilio Vaticano II y con los veinte años de la promulgación del Catecismo de la Iglesia Católica, su Santidad el Papa Benedicto XVI, a través de la Carta Apostólica Porta Fidei, ha declarado un Año de la Fe que abarcaría desde el 11 de Octubre del presente año 2012 hasta el 24 de Noviembre del próximo año 2013. Se desea, en este tiempo, redescubrir el don de la fe, y para ello como hará el propio Pontífice– no se encontrará mejor apoyo que la doctrina de San Agustín de Hipona. Les invito, pues, a atravesar “la puerta de la fe” (Hch. 14,27), que permitirá adentrarnos en la Iglesia para vivir en  comunión con Dios, de la mano del “Doctor más universal y el genio más vigoroso que ha poseído la Iglesia”.
Análisis panorámico de los documentos de la Santa Sede sobre las tecnologías de la información
Authors: Jiménez Carreira Manuel
Published: May 2023

El campo de la comunicación ocupa una extensión muy amplia en la Tradición y en el Magisterio y en de la Iglesia Católica. El objetivo de este artículo es el de hacer un recorrido panorámico por los documentos pontificios y de organismos de la Santa Sede referidos a los medios de comunicación desde la época de la imprenta. Nos detendremos de forma especial en las tecnologías más nuevas, que en su día fueron el cine o la televisión y que hoy están vertebradas por Internet. Esta herramienta está suscitando un interés creciente en los últimos pontificados, en especial en el de Benedicto XVI, a raíz del impulso de la nueva evangelización.
Homilía en la inauguración de curso del Centro de Estudios Teológicos. Sevilla, 26-IX-2012
Authors: Asenjo Pelegrina Juan José
Published: May 2023

.
Fe, Trinidad e Iglesia
Authors: Cordovilla Pérez Ángel
Published: May 2023

Yo creo en Dios en la Iglesia. En esta sencilla expresión puede resumirse lo que intentaremos explicar en estas páginas. Se mostrará la relación recíproca que existe entre el sujeto que realiza el acto de fe al decir yo creo, el contenido de esa fe que es expresada en el Credo (en Dios Padre, Hijo y Espíritu Santo) y el lugar concreto donde es realizado el acto de fe y es entregado su contenido (y en la Iglesia).
A Stateless Key Updation Framework for Enhancing Data Security
Authors: C.Satheesh Pandian  , CMT.Karthikeyan
Published: May 2023

Side-channel analysis (SCA) exploits the data leaked through outputs to reveal the secret key of cytological modules. The important threat of SCA lies within the ability to mount attacks over tiny components of the key and to mixture data over completely different encryptions. The threat of SCA are often dynamic the secret key at each run. Indeed, several contributions within the domain of outflow resilient cryptography tried to attain this goal. However, the projected solutions were computationally intensive and were designed to resolve the matter of the present cytologicalschemes.The generic framework of light-weight key change which will shield the present cytological standards and valuate the minimum necessities for heuristic SCA-security. Propose a whole resolution to shield the implementation of any standard mode of advanced cryptography customary. The answer maintains identical level of SCA-security (and typically better) because the state of the art, at a negligible space overhead whereas doubling the turnout.
DRUG-INDUCED PHOTOSENSITIVITY
Authors: Silva Inês , Auxtero Maria
Published: May 2023

Drug-induced photosensitivity is an abnormal skin reaction in individuals exposed to radiation and certain drugs. A literature review was carried out through a database search of Pubmed, Cochrane Library and Science Direct, in order to identify drugs that cause photosensitivity reactions and acknowledge the role of the pharmacist in the management and prevention of such reactions. Articles dated up to 2020 were included in English, Portuguese and Spanish.The prevalence of photosensitivity reactions depends on factors such as the geographical area and prescription and use habits. Various drug classes, namely NSAIDs (ketoprofen and piroxicam), Antifungals, Antibiotics (tetracyclines, fluoroquinolones), Antihypertensive, Statins, Antiarrhythmics (amiodarone), Retinoids e Chemotherapeutics (vemurafenib), are among the most frequently associated with the induction of photosensitivity reactions. Chronic exposure to these drugs may be associated with an increased risk of photocarcinogenesis.A wide range of drugs, including the ones not subject to medical prescription, may induce photosensitivity, meaning that additional photo-protection precautions must be applied to the patient. The role of the pharmacist plays an important part in the medical counselling, prevention and management of eventual cutaneous reactions associated to these therapeutics.
A ENFERMAGEM DE REABILITAÇÃO NA RECUPERAÇÃO FUNCIONAL DAS PESSOAS COM FRATURAS DE MEMBROS INFERIORES ESTUDO DE CASOS
Authors: Rodrigues Marta , Galvão Joana , Bule Maria , Reis Gorete
Published: May 2023

Introdução: O processo de envelhecimento predispõe à fragilidade. A patologia traumática concorre para a dependência funcional. O Enfermeiro Especialista em Enfermagem de Reabilitação (EEER) tem um papel fundamental na recuperação de status pós fratura, através da intervenção precoce, que possibilita a promoção do autocuidado e a capacitação para a independência funcional. O trabalho tem como objetivo identificar o contributo do EEER, na recuperação da funcionalidade da pessoa após fratura.Método: Estudo de caso de natureza descritiva, segundo a metodologia de estudo de caso de Robert Yin.Foram consideradas duas pessoas, com status pós fratura, durante 4 sessões de reabilitação, que incluíram exercícios articulares e treino de autocuidado, utilizando para colheita de dados e avaliações a Medida de Independência Funcional (MIF).Resultados: Em ambos os casos, verificou-se melhoria da funcionalidade, como expresso pelo aumento do score da MIF.Conclusões: Os resultados sugerem que a intervenção precoce do EEER contribui para o incremento da funcionalidade da pessoa em status pós-fratura, para maior independência.
Impact of Anchoring Management Policy Riau Island Province in Indonesia
Authors: Zhuhendrik Zhuhendrik , Kurnianingsih Fitri , Okparizan Okparizan
Published: May 2023

The existence of waters in the Kepulauan Riau Province at the crossing of international shipping relations brings Indonesia various opportunities for developing valuable environmental and marine services. This research aims to make efforts and alternatives to the optimization strategy of anchorage activities in the Kepulauan Riau Province to manage the potential for environmental and marine services to increase local revenue in the border region. The research method used descriptive qualitative by using secondary data derived from documents, journals, books, websites and other supporting data that focused on analyzing the anchorage development strategy in the waters of the Riau Island Province. The data analysis technique used a data source triangulation approach. The findings show that the impact which occurs in the development of anchorage has three options for optimizing strategies during the COVID-19 pandemic; firstly, maximizing ship guiding and towing services in the Malacca Strait and Singapore Strait, secondly, ship guiding and towing services at TUKS and TERSUS must be given the authority to the Regional Owned Enterprises (BUMD), namely P.T. Pelabuhan Kepri; and thirdly, the importance of controlling environmental impacts on anchorage activities in the Kepulauan Riau Province. Afterwards, the researcher also provides an alternative to implementing the Penta-helix concept as a form of monitoring anchors in the waters of the Kepulauan Riau Province.
Literature Review on Auditor Independence
Authors: Masyitah Emi
Published: May 2023

This study aims to provide an overview of the development of auditor independence research. Data were taken from articles published in Scopus indexed international journals from American Accounting Association publishers, Emerald, Wiley, Elsevier, Routledge, Academic Press Inc, and Taylor and Francis Ltd. Samples were taken from 2002 to 2022 as many as 27 auditor independence articles. The method of analysis is through classifying articles based on the research method used, the name of the journal, the year of publication, and the country of origin of the first author. In general, the results of the study found that research on auditor independence has increased from year to year and is still an interesting research topic to study.
Application of Information Systems at PT Angkasa Pura II Silangit Airport
Authors: Kurnia Sari Ayu , Saputra Hendra , Ku Ariffin Ku Halim Bin
Published: May 2023

PT Angkasa Pura II (Persero) is one of the State-owned Enterprises engaged in the business of airport services and services linked to the air city. The purpose of the research is to analyze the accounting data system at PT. Angkasa Pura II Silangit. This research uses descriptive research methods. From the results of this research, it can be seen that the accounting data system presented by the industry is stored and recorded in SAP. Strandar is used to view code in processing and inputting every transaction contained in industrial activities. PT. Angkasa Pura already has a very complete accounting data system, this system can be connected to all components of central and branch activities. In manual use, this system has been designed very well but must be checked and memorized in use with SAP that has been available. Employees cannot use the system carelessly and the code must also be able to be adjusted properly.
Implications of Limited Liability Company After Being Declared Bankrupt
Authors: Hadrian Endang
Published: May 2023

Bankruptcy is a situation where a debtor is unable to pay his debts and can be billed. Companies that have been declared bankrupt in this case must be dissolved in order to change their legal entity status so as not to cause losses to related parties. A limited liability company that is declared bankrupt does not immediately stop and disband but still exists as a legal entity. Under certain circumstances, it continues to operate as usual, the limited liability company does not go bankrupt and can still carry out its business activities. This study formulates two problems, namely first, what is the process for dissolving a Limited Liability Company after being declared bankrupt? and second, what are the implications of a Limited Liability Company after being declared bankrupt. The type of research used in this case is normative juridical. Legal research conducted by reviewing the literature is referred to as secondary data. The results of this study are that liquidation is processed by first holding a General Meeting of Shareholders and the implication is that a Limited Liability Company after being declared bankrupt makes the company lose its right to manage and control the company's assets
Protein Quality Analysis of Baby Porridge, Soybean Protein Concentrate, Rebon and Casein Against Weight Gain in Experimental Rats
Authors: Talahatu Anna Henny
Published: May 2023

Protein quality is assessed based on the speed of growth that occurs after consuming and digesting something protein and the amount of nitrogen absorbed or used by the body. Complete protein can ensure good body growth and can maintain or replace damaged body tissues while incomplete protein although it cannot guarantee growth but is able to maintain body tissues. The purpose of this study to determine high-quality protein food sources can be seen from the value of protein quality indicators, including Protein Efficiency Ratio (PER), Biological Value (BV), Net Protein Utilization (NPU), Net Protein Ratio (NPR), True Digestibility (Dt) and Apparent Digestibility (Da). The research design developed in this study is an experiment using experimental mice with indicators of weight gain and protein quality in some foods. The results showed that the average weight gain (8.5 gr) of the largest rats was rats given baby porridge in their diet, as for weight loss (-2.4 gr) of rats given soy protein concentrate (KPK) in their diet. Furthermore, from the assessment of protein quality, it is known that the highest PER value is baby porridge (10.03), the highest BV value is soy protein concentrate (KPK: 0.99), the highest NPU value is soy protein concentrate (KPK: 1.28) and casein (1.23), the highest NPR value is baby porridge (0.13) while the Dt value (protein / casein 1.36) and Da for all types of protein tested are almost the same.
PENGARUH RISIKO INFLASI TERHADAP TINGKAT RETURN SAHAM DI PT. UNILEVER TAHUN 2015 - 2019
Authors: Julita Saffanah , Manda Gusgana Suria
Published: May 2023

This study aims to determine the impact of inflation in Indonesia on stock returns at PT. Unilever 2015 – 2019. In determining the impact of inflation on stock returns, data that is relevant to the title of the study is needed. This research method is a quantitative research method, the data collection method is a secondary data collection method derived from journals, final assignments, and books that are relevant to this research. Furthermore, for the data analysis method used quantitative descriptive analysis method with stock return data used which means the difference between stock prices in the current period and stock prices in the previous period (capital gain loss). The results of this study indicate that inflation has no effect on the value of stock returns at PT. Unilever in 2015 – 2019.
Hidrólise da proteina do Grilo Preto (Gryllus assimilis) potencializada por ultrassom: efeito na cinética de hidrólise, solubilidade e atividade antioxidante
Authors:   , Justino Heloísa de Fátima Mendes
Published: May 2023

A população mundial encontra-se em crescimento, ocasionando a busca constante por novas fontes de alimentos que possuam alto valor nutricional e sejam produzidas de maneira sustentável. O Grilo Preto (Gryllus assimilis) é uma fonte de proteína com grande potencial de uso na obtenção de peptídeos bioativos e técnico-funcionais. Atualmente, a hidrólise enzimática é o principal método de obtenção desses peptídeos, porém possui desvantagens tecnológicas como o longo tempo de processo, alto custo e baixo rendimento. Nesse sentido, o uso de tecnologias emergentes, como o ultrassom (US), têm sido uma estratégia empregada para melhorar a performance enzimática e otimizar o processo de obtenção dos hidrolisados. Este estudo investigou a aplicação da tecnologia de ultrassom como potencializadora da hidrólise enzimática das proteinas de grilo preto (Gryllus assimilis) e seu impacto na solubilidade e atividade antioxidante dos hidrolisados obtidos. Primeiramente foi testada a aplicação do ultrassom (23,8 W/L, 25 kHz/ 25, 40 ou 60 °C/ ate 180 min) sobre enzima (Alcalase®) e substrato (Gryllus assimilis) separadamente. A avaliação dos processos foi realizada pela determinação da atividade enzimática obtida com a enzima sonicada ou sobre o substrato processado, sendo observados, como melhores resultados, aumentos que variaram de 59,4 a 148,5% após processamento de enzima (30 min a 25°C) e substrato (30 min a 40°C), respectivamente. Os ensaios cineticos mostraram que a hidrolise da proteina de grilo preto (PGP) sob estas condições de maior aumento de atividade alcançadas pela pré- sonicação ou em reações assistidas por US resultou em um aumento de até 227% na taxa de proteólise. Além disso, a utilização do PGP pré-processada por US (30'/40ºC) aumentou o grau de hidrólise em 52,2% comparado ao processo convencional após 180 min de reação à 60 “C. Consequentemente, os hidrolisados obtidos com a intervenção do US apresentaram melhor capacidade antioxidante (47,8 para DPPH e 113,6% para ABTS) e maior solubilidade (9,7%) em relação aqueles obtidos pela hidrólise convencional. Portanto, a utilização do banho ultrassônico, tanto no pré-tratamento do substrato como para realização de hidrólise assistida, se mostrou uma estratégia promissora para aplicação na industria alimentícia visando potencializar a produção de hidrolisados com melhores propriedades biológicas e técnico-funcionais. Palavras-chave: Grau de hidrólise. Grilo Preto. Propriedades biológicas. Propriedades técnico-funcionais. Proteína de inseto. Sonicação.
The Effect of Job Satisfaction and Employee Commitment on Employee Performance at the Social Service of Makassar City
Authors: Karmila Maharani  , Romansyah Sahabuddin  , Tenri S.P. Dipoatmodjo  , Burhanuddin  , Zainal Ruma
Published: May 2023

This study aims to (1) determine the effect of job satisfaction on employee performance, (2) determine the effect of employee commitment on employee performance, (3) determine the effect of job satisfaction and employee commitment jointly on employee performance at the Makassar City Social Service . The data used in this study are primary and secondary data with a total sample of 69 respondents. This study used a quantitative approach and was analyzed using multiple linear regression analysis with the help of SPSS 22 data processing to prove three hypotheses. The results of this study prove that the variable Job Satisfaction has a significant effect on Employee Performance with a t count of 2.964 > t table of 1.996. The Employee Commitment variable has a significant effect with a t count of 2.943 > t table of 1.996. Based on the results of this study it is also known that the independent variables jointly or simultaneously have a positive and significant effect on the dependent variable, namely Employee Performance at the Makassar City Social Service. Therefore, if job satisfaction and employee commitment continue to be improved, it will certainly increase employee performance.
SISTEM PENDETEKSI JARAK OBJEK UNTUK TUNANETRA BERBASIS MIKROKONTROLER DAN ANDROID
Authors: Junaedy Junaedy , Lukman Musfirah Putri
Published: May 2023

Tunanetra merupakan sebutan sebagai orang yang memiliki keterbatasan dalam melihat. Tunanetra saat ini masih menggunakan alat konvensional untuk berjalan dalam kegiatan sehari-harinya. Adapun juga kerabat dari tunanetra tidak mengetahui keberadaan tunanetra jika sedang dicari. Penelitian ini bertujuan untuk mengimplementasikan sensor ultrasonik, modul suara, dan pendeteksian lokasi tunanetra melalui smartphone dimana penelitian ini mengembangkan sistem yang memudahkan tunanetra khususnya saat berjalan dan melakukan aktivitas sehari-hari serta memiliki tujuan untuk membantu kerabat dari tunanetra untuk memantau aktivitas tunanetra melalui lokasi keberadaannya. Adapun metode yang digunakan dalam proses pembuatan sistem ini yakni Metode Waterfall dalam pembuatan alat dan Black Box Testing dalam proses pengujian sistem alat dan aplikasi. Hasil akhir dari penelitan ini yakni penulis berhasil mengimplementasikan sistem pendeteksi jarak objek untuk tunanetra berbasis mikrokontroler dan android. Pada penelitian ini alat akan mendeteksi adanya objek dalam rentang 75 cm ke bawah dengan tingkat akurasi sebesar 80% dari pengujian yang telah dilakukan dan nilai error sebesar 20%.
ALAT KONTROL AKSES PINTU MENGGUNAKAN SIDIK JARI DENGAN NOTIFIKASI TELEGRAM BERBASIS IOT
Authors: Hanafie Ahmad , Husain Nursuci Putri , Sukirman Sukirman , Nurhidayah Ulfa
Published: May 2023

Keamanan sistem dalam rumah atau tempat tinggal yang kurang ketat dapat menyebabkan hal-hal yang tidak diinginkan seperti pencurian dll. Oleh karena itu dibutuhkan suatu perangkat sistem keamanan untuk dapat menjaga keamanan setiap waktu bahakan melindungi aset dan privasi yang dimiliki. Tujuan penelitian ini untuk merancang dan menguji sistem akses pintu menggunakan sidik jari dengan notifikasi telegram. Metode yang digunakan berupa penelitian terdahulu yang serupa. Data yang yang diperoleh kemudian dianalisis menggunakan metode Analisa SWOT (Strenght, Weaknes, Opportunities, Threats). Cara kerja alat ini yaitu setiap sidik jari memiliki ID yang tersimpan dalam database Arduino, jika sensor fingerprint mendeteksi kemiripan sidik jari maka Arduino secara otomatis akan membuka pintu, informasi ini juga akan dikirim melalui Telegram ke pemilik rumah sebagai notifikasi bahwa telah terdeteksi sidik jari pada fingerprint. Hasil yang diperoleh adalah rancangan Alat kontrol akses pintu menggunakan sidik jari dengan notifikasi telegram, dirancang menggunakan Arduino Uno sebagai pusat kendali. Pengujian diperoleh jika sidik jari teridentifikasi cocok pintu akan terbuka dan membutuhkan waktu notifikasi masuk  2.3 detik, sensor mendeteksi adanya pembukaan pintu secara paksa buzzer berbunyi dan membutuhkan waktu notifikasi masuk   detik. Dapat disimpulkan bahwa alat pengamana pintu menggunakan sidik jari dan Arduino Uno sebagai pusat kendali dengan modul esp32 untuk mengirimkan informasi ke telegram. Alat ini sudah dapat diimplementasikan pada pintu dengan skala prototype.
RANCANG BANGUN ALAT PENGUSIR BURUNG PEMAKAN BUAH BERBASIS SUARA ULTRASONIC
Authors: Muddin Saripuddin , Kamal Kamal , Lianti Lianti , Yuhardianti Yuhardianti
Published: May 2023

Burung pemakan buah sulit  dikendalikan, Dan masalah yang dihadapi  petani  dapat menyebabkan gagal panen. Penelitian ini bertujuan untuk menghasilkan alat pengusir burung berbasis suara ultrasonic  dan untuk mengetahui hasil pengujian serta  implementasi alat pengusir burung berbasis suara ultrasonic. Metode penelitian yang digunakan adalah R&D, diagram alir dan diagram blok yang menunjukkan tahapan perancangan perangkat sel surya yang mengubah panas dari matahari menjadi energi listrik, baterai yang menyimpan listrik, saklar yang mengontrol arus, Dan sensor untuk pendeteksi gerakan. Hasil desain pengusir burung pemakan buah berbasis suara ultrasonic dapat mendeteksi gerakan hingga jarak 5 meter dan mengusir hama burung hingga jarak 15 meter. Alat ini mengeluarkan suara selama 10 detik setiap kali gerakan terdeteksi. Dari hasil pengujian serta implementasi  bahwa Semua  alat ini berfungsi persis seperti yang diinginkan dan diharapkan oleh peneliti. Dapat disimpulkan bahwa pengusir burung pemakan buah berbasis suara ultrasonic dapat membantu petani dalam mengusir hama burung pemakan buah.
PERANCANGAN ALAT BLOCKING JARINGAN SMARTPHONE 3G DAN 4G SECARA OTOMATIS PADA AREA MESJID
Authors: Muddin Saripuddin , Alamsyah Nur , Rahayu Sri , Ardi M Ardi M
Published: May 2023

Seringnya terjadi gangguan smartphone saat melaksanakan ibadah oleh sebab itu kami membuat alat yang dapat mengcegah adanya gangguan smartphone dalam mesjid.penelitian ini bertujuan untuk melakukan perangcangan alat, pengujian sistem serta melakukan pengukuran jarak yang dapat dijangkau oleh jammer.metode yang digunakan yaitu membuat desain rancangan, pengadaan alat, bahan, pengerjaan alat lab teknik, pengujian sistem dengan memberikan arus listrik 220 volt untuk memastikan semua komponen berfungsi dengan baik serta  pengujian jammer otomatis ON dan OFF pada waktu shalat , pengujian jamming pada jaringan 3G, 4G pada sinyal GSM (Telkomsel, Indosat, XL, Tri), CDMA (smartfren) kemudian pengukuran jarak jangkauan jammer menggukan meter yang di lakukan di mesjid dan  pengujian jarak jangkaun jammer  dengan dua tembok yang menghalangi sinyal. Hasil yang dapat di ambil dari penelitian ini yakni perangcangan dan pembuatan alat bloking jaringan smartphone 3G dan 4G  secara otomatis pada area mesjid mampu berfungsi dengan baik  saat mematikan dan menghidupkan jammer pada waktu shalat. Kesimpulan dari pengujian alat ini mampu menghilangkan jaringan 3G dan 4G pada radius 10 meter serta pengujian dengan menggunakan penghalang pada percobaan 5 meter mampu menghilangka jaringan 3G dan 4G pada radius 4 meter.
Effect of cigarette smoking on blood parameters in young smokers
Authors: Sulaiman Musa Marwah Isam
Published: May 2023

This study set out to evaluate the detrimental impact of cigarette smoking on the metabolic characteristics of smokers, looking at how smoking altered physiological factors differently for both smokers and nonsmokers. The results showed a significant difference in hemoglobin content, a gauge of blood oxygenation, between smokers and non-smokers. The findings of the current investigation enable us to reach the following judgment: Leukocytes, average erythrocyte volume, and average hemoglobin content in erythrocytes are all increased by smoking cigarettes on a regular basis. These changes could raise the risk of cardiovascular disease, polycythemia, pulmonary disease, and/or atherosclerosis. According to the number of years of smoking, the groups of smokers in the analysis were divided, with smoking periods of 10 years or longer being the longest
Influence of Self-Efficacy Competences on Management of Scholarly Information among Postgraduate Students in Kiambu County Kenya
Authors: Njiru Leah , Thinguri Ruth , Chui Mary
Published: May 2023

Purpose: The study investigates the effects of student literacy self-efficacy competences on management of scholarly information among postgraduate students in Kiambu county Kenya. Self-efficacy is a tool in information literacy.

Methodology: The study adopted a mixed methodology so as to collect and analyze qualitative and quantitative data where data was collected using self-administered questionnaires.

Findings: The findings of the study revealed that self-efficacy as a practice of information literacy influence Management of Scholarly Information.

Unique Contribution to Theory, Practice and Policy: The paper recommends that more attention be given to the practice of self-efficacy competence since it’s a vital factor evaluate to quality papers among scholars. Further studies should evaluate the extent to which self-efficacy influence postgraduate scholars on their scholarly information management.
Leading Technological Change – Case Study of Emirates Airlines
Authors: Naqeeb Ahmad , Darwish Hessa , Alhajri Reem
Published: May 2023

Purpose: Emirates Airlines is one of the leading airlines with over 100 international destinations. The airline sector is continually evolving, bringing both difficulties and possibilities. Emirates Airlines has reacted to these changes by effecting an organizational change plan. Implementing a Resource Management System (RMS) in the line maintenance department is the primary subject of this study since it was the main change in the Emirates. Based on specified criteria and flight updates, the RMS software program produces jobs for technicians and engineers. Therefore the study aims to evaluate how the organization handles the change process after introducing new technological applications in the emirates airlines.

Methodology: This study employs various qualitative research techniques, including interviews.

Findings: The study reveals that critical leadership traits for implementing change include self-awareness, self-regulation, empathy, self-motivation, and social skills. Embracing change enables organizations to enhance their services and provide a distinct competitive edge compared to resistance, which can render the firm irrelevant. Resistance to change mainly occurs due to inadequate information, poor comprehension, and varying visions (Elgohary & Abdelazyz, 2020).

Unique Contribution to Theory, Practice and Policy: The study was anchored on change model. The study recommends that the RMS should benefits the department by improving labor utilization, lowering maintenance costs, and raising customer satisfaction.
A Review of the Integrated Creative Arts Curriculum Implementation in Nigerian Teacher Education Colleges
Authors: Clare Dr. Kubra
Published: May 2023

Purpose: The purpose of this study is to evaluate the implementation of Integrated Creative Arts (ICA) curriculum in Teacher Education Colleges (TECs) in Nigeria.

Methodology: The paper used a desk study review methodology where relevant empirical literature was reviewed to identify main themes and to extract knowledge gaps.

Findings: The study concluded that the lack of schemes of work, lesson plans, ICA syllabus and handbooks has a negative an impact on the implementation of ICA curriculum in TECs in Nigeria.

Unique Contribution to Theory, Practice and Policy: The study recommends that the college management should make it a point of duty to avail art rooms, workshops and music rooms in all Teachers Education Colleges (TECs) with adequate provision of equipment, and tools this will make teaching and learning of the subject to be meaningful, as the students will have the opportunity to be engaging in practical works, which is the major aspect of the curriculum; Instructional materials should be provided and their usage be made compulsory in TECs.
Peran Madrasatul Ula Dalam Pembentukan Kecerdasan Spiritual Anak
Authors: Mulasi Syibral
Published: May 2023

Pembahasan ini bertujuan untuk melihat peran orangtua sebagai madrasatul ula dalam pembentukan kecerdasan spiritualitas anak, dalam Islam dikatakan orangtua sebagai guru yang paling utama (madrasatuul ula) bagi anak-anaknya, maka selayaknya mampu menjalankan peran mereka sesuai konteks yang diajarkan Rasulullah Saw, pembahasan ini menggunakan pendekatan kualitaif dengan metode analis tesk baik dari ayat ayat Al-Qur‟an maupun Hadits Rasulullah Saw dan serta tulisan yang berkaitan dengan tema pembahasan. Dari hasil kajian ditemukan bahwa peran orangtua sebagai madrasatul ula sangatlah menentukan arah pembentukan kepribadian anak, orangtua yang tidak mampu menjalankan perannya dengan baik dan maksimal akan berpengaruh langsung terhadap sikap religiusitas anak, disamping itu dalam membentuk anak yang baik sudah selayaknya orangtua memberikan teladan yang baik bagi anak, mendidik anak dengan akhlakul karimah, selalu menasehati serta harus selalu memproteksi setiap apa yang mereka lakukan dan membimbing serta mengarahkan anak dari setiap kesalahan yang telah mereka lakukan anak.