bluuebunny/crossref_metadata_2025 huggingface dataset:
Initial experience with gamma knife surgery for endocrine ophthalmopathy
Authors: Antico Julio C. , Crovetto Luis , Tenca Eduardo , Artes Carlos
Published: November 2018

Object. The aim of this study was to evaluate both the effectiveness and safety of the treatment of endocrine ophthalmopathy with gamma knife surgery (GKS).

Methods. Five patients were included in a prospective study designed to assess the results of GKS of endocrine ophthalmopathy secondary to Graves disease. All the patients completed a 2-year follow-up period. During this period, the patients were evaluated both clinically and by means of additional methods, including computerized tomography and magnetic resonance imaging studies. The minimum dose delivered to the 50% isodose line was 6.5 Gy in all the patients.

In all cases, a clinical improvement was observed. The best effect was seen in symptom regression related to soft-tissue involvement. No treatment-related side effects were detected.

Conclusions. In light of the results obtained the authors consider that GKS may be a safe and effective way to treat endocrine ophthalmopathy.
Gamma knife surgery for atypical meningiomas
Authors: Huffmann Beate C. , Reinacher Peter C. , Gilsbach Joachim M.
Published: November 2018

Object. Complete resection is the optimal treatment for atypical meningiomas (AMs) but its feasibility depends on the tumor site. The object of this study was to assess the effect of gamma knife surgery (GKS) on AM.

Methods. In 15 patients 21 AMs were treated by GKS. Four patients had residual lesions and 10 patients had recurrent tumors after one or more microsurgical interventions. Three patients were treated twice with GKS because of tumor tissue outside the treatment volume, either at the margin or at a distant location. The median clinical and neuroimaging follow-up period was 35 months (range 21–67 months).

Ten tumors shrank 6 to 12 months after GKS, 10 remained stable, and one grew. Between 18 and 36 months after GKS, four patients had a distant recurrence, and two had a margin recurrence. In one of these cases, an additional local recurrence was demonstrated 1 year later, and the patient underwent standard radiotherapy. No patient suffered persistent adverse effects after radiosurgery.

Conclusions. After early tumor shrinkage, high recurrence rates were demonstrated both at the treatment margin and at distant locations in cases treated for AM. There was only one recurrence within the GKS radiation field. For small- and medium-sized AMs GKS may be a safe adjunct to other treatment modalities.
Tumor recurrence and survival following gamma knife surgery for brain metastases
Authors: Mindermann Thomas
Published: November 2018

Object. The authors evaluated prognostic factors for tumor recurrence and patient survival following gamma knife surgery (GKS) for brain metastasis.

Methods. A retrospective review of 101 patient charts was undertaken for those patients treated with GKS for brain metastases from 1994 to 2001.

Recurrence rates of brain metastasis following GKS depended on the duration of patient survival. Long-term survival was associated with a higher risk of tumor recurrence and shorter-term survival was associated with a lower risk. The duration of survival following GKS for brain metastases seems to be characteristic of the primary disease rather than the cerebral disease.

Conclusions. Recurrence rates of brain metastasis following GKS are related to duration of survival, which is in turn mostly dependent on the nature and course of the primary tumor.
Control of growth of vestibular schwannomas with low-dose Gamma Knife surgery
Authors: Hudgins W. Robert , Antes Kyle J. , Herbert Morley A. , Weiner Richard L. , Desaloms J. Michael , Stamos Denise , Barker Jerry L. , Echt Gregory A. , Nichols Timothy D. , Schwarz Donald E.
Published: November 2018

Object

The treatment of solitary vestibular schwannomas by performing Gamma Knife surgery is well established. It has been reported that decreasing the surface dose reduces patient morbidity, especially facial weakness and numbness. The authors of this retrospective study examine patient data from a single center to determine if low-dose (≤ 14 Gy) GKS controls tumor growth as effectively as higher doses (> 14 Gy).

Methods

Based on the formula for ellipsoid volumes, the tumor volumes were calculated using measurements from MR images obtained at follow up in patients treated at the authors' center. Follow-up data were available in 159 patients with a mean age of 59.5 ± 14.2 years at treatment. Fifty-six percent of the patients were women and 53.5% of the tumors were located on the right side of the brain. The mean tumor volume was 3.3 ± 4.3 cm3 with 10% of the tumors having volumes larger than 8 cm3. After GKS, smaller tumors (≥ 40% decrease in volume) were observed in 44.8% of patients treated with a low dose and in 48.8% treated with a high dose. Enlarged tumors (≥ 40% increase in volume) were seen in 5.2% of the patients receiving a low dose and 2.3% of those receiving a high dose. These differences were not statistically significant.

Patients who had been followed up for longer than 5 years after treatment had median residual volumes of only 28.2% of the starting volume in the low-dose group and 26% in the high-dose group. This difference was statistically not significant.

Conclusions

No statistically significant differences were observed between tumors given low-dose radiation treatment and those given high-dose radiation treatment.
Utility of apparent diffusion coefficient in predicting the outcome of Gamma Knife–treated brain metastases prior to changes in tumor volume: a preliminary study
Authors: Goldman Marc , Boxerman Jerrold L. , Rogg Jeffrey M. , Norén Georg
Published: November 2018

Object

Gamma Knife surgery (GKS) is often the sole treatment for brain metastases. The authors hypothesized that early post-GKS measures of the relative apparent diffusion coefficient (rADC) could predict therapeutic response, recurrence, and radionecrosis prior to changes in tumor volume.

Methods

Magnetic resonance (MR) images of 25 metastatic tumors in 15 patients were reviewed. Inclusion criteria included a history of surgery or GKS, a minimum tumor diameter of 5 mm at treatment, and a minimum of two follow-up MR images. Tumor volumes were normalized to baseline, and tumor ADC values were normalized to normal-appearing white matter (rADC). A successful therapeutic response (STR) was defined by a monotonically decreasing tumor volume throughout the follow-up period. Magnetic resonance spectroscopy was used to classify non-STRs as radionecrosis or tumor recurrence.

All tumors exhibited a decreased normalized volume (mean 37%) at the first follow-up examination (range 33–124 days after GKS, mean 54 days), and three distinct rADC patterns subsequently evolved: Group 1 (STR [10 cases]), monotonically decreasing volume with gradually increasing rADC; Group 2 (radionecrosis [three cases]), initial volume reduction followed by gradual increase, with initial rapidly increasing rADC followed by more gradual increase or plateau; and Group 3 (recurrent tumor [12 cases]), initial volume decrease followed by increase, with a preceding gradual decrease in the rADC.

Conclusions

The rADC patterns outperform initial post-GKS tumor volume in predicting the long-term response to treatment. Decreasing tumor volume with an increasing rADC predicts an STR. For lesions with increasing volume, antecedent rADC reduction predicts recurrence, whereas a rapidly increasing rADC predicts radionecrosis. Evaluation of the rADC at the initial post-GKS follow-up examination appears to be a useful prognostic measure of metastatic tumor response.
Gamma Knife surgery for multiple brain metastases from a malignant schwannoma of the penis
Authors: Eck Albertus T. C. J. van , Horstmann Gerhard A.
Published: November 2018

✓The occurrence of brain metastases from a malignant schwannoma of the penis is extremely rare. In patients with a single brain metastasis, microsurgical extirpation is the treatment of choice and verifies the diagnosis. In cases of multiple or recurrent metastases, radiosurgery is an effective and safe therapy option. Gamma Knife surgery was performed in a patient who had previously undergone tumor resection and who presented with recurrence of the lesion and three de novo brain metastases. This first report on brain metastasis from a malignant penile schwannoma illustrates the efficacy and safety of radiosurgical treatment for these tumors.
Gamma Knife surgery for metastatic brain tumors without prophylactic whole-brain radiotherapy: results in 1000 consecutive cases
Authors: Serizawa Toru , Higuchi Yoshinori , Ono Junichi , Matsuda Shinji , Nagano Osamu , Iwadate Yasuo , Saeki Naokatsu
Published: November 2018

Object

The authors analyzed the effectiveness of Gamma Knife surgery (GKS) for metastatic brain tumors without adjuvant prophylactic whole-brain radiotherapy (WBRT). Salvage GKS was performed as the sole treatment for new distant lesions.

Methods

Among 1127 patients in whom new brain metastases had been diagnosed, 97 who met one or more of the following three criteria were excluded from the study: any surgically inaccessible huge (≥ 35 mm) lesion; tumor number and size requiring an internal skull dose exceeding 10 J; or symptomatic carcinomatous meningitis. Thus, 1030 consecutive patients formed the basis for this study. Huge tumors were totally removed, whereas smaller lesions were treated with GKS. No adjuvant WBRT was given prior to GKS, and new distant lesions were appropriately retreated with GKS. Overall, neurological and new lesion–free survival curves were calculated and the prognostic values of covariates were obtained. In total, 1853 separate GKS sessions were required to treat 10,163 lesions.The patients' median overall survival period was 8.6 months. Neurological survival and new lesion–free rates at 1 year were 89.1 and 49.3%, respectively. In a multivariate analysis, the significant factors for poor prognosis were the development of more than four new brain metastases and active extracranial disease.

Conclusions

In meeting the goal of preventing neurological death and maintaining activities of daily living for patients with brain metastases, GKS alone provides excellent palliation without prophylactic WBRT. New distant lesions were quite well controlled with GKS salvage treatment alone.
Book Publishing in the Context of Digital Economy: A Statistical Analysis
Authors: Horobets O. O.
Published: November 2018

In the era of the digital economy, books should continue to be relevant to modern society, and book publishing needs to be a competitive industry in the market. Therefore, the statistical analysis of world book publishing is necessary to determine the landmark movement for domestic publishers supposed to find a solid niche in the digital economy.
Book publishing is an economic activity which effectiveness is measured by not only publication figures but by the level of education and consciousness of the nation, demonstrating its intellectual capacity to the whole world.
The article gives an example of a successful online Amazon business. The state of popularity of the e-book in France, Korea, and China is investigated. A statistical analysis of book publishing of Ukraine is presented. The dynamics of the increase of Internet subscribers in the territory of Ukraine was observed. The dynamics of the main indicators presented in the tables is simulated. The simulation results showed that the time dependence of the number of published books and brochures, as well as the total circulation of publications, is best described by the polynomial of the fourth degree, Internet subscribers – the polynomial of the third degree. Summarizing the analysis, it was concluded that the years 2014 and 2015, when indicators and number of publications and circulation have rapidly decreased, are critical for book printing, as well as for almost all spheres of life of Ukraine, the first – from 26323 thousand units. in 2013 to 19958 thousand units. in 2015, the circulation during this time decreased by almost one and a half times. Taking into account the number of the population of Ukraine as of 2017 (44.03 million people), the indicators of the book publishing industry can be argued that the index of bookkeeping of Ukraine by 2017 was 1.02 books per person.
Las fotografías más antiguas del AGN, en papel salado, procedentes del registro de ladrones de la Cárcel Nacional de Belem
Authors: Quintero Barajas Ana Lilia
Published: November 2018

Los documentos históricos sobre soporte fotográfico más antiguos con que cuenta el Archivo General de la Nación forman parte de dos expedientes del Fondo Archivo de Guerra, son copias al papel salado con fechas de manufactura aproximada de abril y junio de 1855. Fueron hechas presumiblemente por el coronel José Muñoz, Fotógrafo de la Cárcel Nacional de Belem y responden históricamente a la necesidad política de nuestro país de reglamentar y renovar el sistema jurídico y penitenciario utilizando la fotografía como un adelanto científico útil para el control y clasificación de los criminales. La toma de retratos para la identificación de reos permite reconstruir las gestiones administrativas de la Comandancia de la Ciudad de México para la administración de justicia.
Expert knowledge-infused deep learning for automatic lung nodule detection
Authors: Tan Jiaxing , Huo Yumei , Liang Zhengrong , Li Lihong
Published: November 2018

BACKGROUND:

Computer aided detection (CADe) of pulmonary nodules from computed tomography (CT) is crucial for early diagnosis of lung cancer. Self-learned features obtained by training datasets via deep learning have facilitated CADe of the nodules. However, the complexity of CT lung images renders a challenge of extracting effective features by self-learning only. This condition is exacerbated for limited size of datasets. On the other hand, the engineered features have been widely studied.

OBJECTIVE:

We proposed a novel nodule CADe which aims to relieve the challenge by the use of available engineered features to prevent convolution neural networks (CNN) from overfitting under dataset limitation and reduce the running-time complexity of self-learning.

METHODS:

The CADe methodology infuses adequately the engineered features, particularly texture features, into the deep learning process.

RESULTS:

The methodology was validated on 208 patients with at least one juxta-pleural nodule from the public LIDC-IDRI database. Results demonstrated that the methodology achieves a sensitivity of 88% with 1.9 false positives per scan and a sensitivity of 94.01% with 4.01 false positives per scan.

CONCLUSIONS:

The methodology shows high performance compared with the state-of-the-art results, in terms of accuracy and efficiency, from both existing CNN-based approaches and engineered feature-based classifications.
Volkspartei neuen Typs?
Authors: Niethammer Lutz
Published: November 2018

Im folgenden Beitrag wird die Geschichte der SED als Abfolge unterschiedlicher Generationenbiindnisse dargestellt. Dabei zeigt sich, daß sich die SED nur zu einem geringen Teil aus der Arbeiterklasse selbst rekrutiert und zum größeren Teil aus aufgestiegenen Mitgliedern, die ihre Prägung nicht zuletzt im Nationalsozialismus e1fuhren.
Research of functional and technological properties of minced meat products with using fish raw materials
Authors: Matsuk Y. , Marchenko I. , Pasichnyi V.
Published: November 2018

The article is devoted to the improvement of the recipes of minced meat products with using fish raw materials and the study of organoleptic and functional and technological properties of developed minced meat systems and finished products. The research has been carried out on the rational combining of meat and fish raw materials and the expansion of assortment of minced semi-finished products. The formulations of minced meat systems for the production of meat semi-finished with a partial replacement of the main raw material to fish raw materials have been developed. The organoleptic and functional and technological parameters of minced meat systems and finished products are investigated. According to the results of the organoleptic evaluation, it was found that partial replacement of meat raw material with minced fish does not worsen the sensory characteristics of minced meat products. It is established that in comparison with the control sample there is an improvement of functional and technological indicators. In particular, the moisture content increased by an average of 6.1%, moisture absorption capacity – 5.91%, energy absorption capacity – 2.49%, fat-retaining ability – 2.52%. The obtained results confirmed the expediency of using minced meat with pollack in the technology of minced meat semi-finished products with due observance of the parameters of production cycle of heat treatment of products. It has been theoretically substantiated and experimentally confirmed the technology of meat products using minced meat and developed recipes. It has been established that with careful selection of components that are part of minced meat semi-finished products with the addition of fish raw materials can increase the organoleptic and functional and technological parameters of finished products. The obtained data suggest that the improved recipes of minced meat semi-finished products can be recommended for production by enterprises of the meat industry and restaurants
The estimation of effects of food crioprotectors on quality indicators of semi-fragrances
Authors: Skochko O. I. , Shevchenko I. I. , Polichuk G. E. , Paska M. Z.
Published: November 2018

A prerequisite for the preservation of quality indices of truncated semi-finished products after defrosting is compliance with the recommended conditions of refrigeration. However, it is not always possible to maintain high consumer properties of frozen semi-finished products, as the degree of destructive influence of low minus temperatures on muscle fibers of meat raw materials also depends on its quality. In world practice, the issue of the use of physico-chemical methods of treating biotechnological objects is often discussed with the use of substances of cryoprotective action. In order to stabilize the functional and technological properties of low-grade meat raw material and protect frozen brooded semifinished products from the negative influence of physico-chemical factors, protein-hydrocarbon compositions of cryoprotective action were developed. According to the results of the research, the use of Vepro 75 PSC, sodium caseinate and vegetable fiber (wheat, flax, plantain) as part of semi-finished products helps to obtain high quality products with stable consumer properties. Stabilizing effect of protein-polysaccharide mixtures ... in the model samples, the cutlet manifests itself in improving their consistency, increasing juicing and other quality indicators. The most effective composition of the complex cryoprotective protein-polysaccharide mixture containing the blood plasma protein, sodium caseinate, plantain fiber and flaxseed was determined in equal proportions. It was established that the use of developed cryoprotective complex mixtures in the model of meat minced meat systems in the amount of 2% reduces the cryoscopic temperature by 2.09–2.81 ºС, reduces the mass fraction of frozen moisture by 0.9% and increases the moisture content capable of 9.7–15.3%, in comparison with the control sample, which positively affects the quality indices of finished products. According to the results of the conducted research, it was found that the use of protein-carbohydrate compositions in the half-finished semifinished products can preserve the dense structure and succulence of the semi-finished products after 30 days of storage in the frozen state. It is confirmed that the mechanism of cryoprotective action of the developed protein-polysaccharide compositions is associated with a decrease in water activity, the formation of an amorphous structure within the product and a decrease in the number of crystallization centers.
The estimation of the parameter Gruneisen metal hexaborides
Authors: Fedyshyn Y. , Vadets D. , Garashchenko O. , Romanov O. , Fedyshyn T.
Published: November 2018

The basis for the estimation of the Gruneisen parameter γ is laid  (θД – Debye’s characteristic temperature, V– molar volume) from which the mathematical expression follows . In previous publications in order to determine θД the Lindemann formula was used. However, due to the ambiguity of the dimensional coefficient C in the Lindemann formula, the authors used the method of high-temperature roentgenography within the limits of 293–973 K. On the basis of analisys of the intensity of one maximum interference (hkl) at different temperatures, was determined by Chipman’s method X-ray characteristic temperature  θр(Т) groups of hexaboard type CaB6, namely CaB6, YB6, LaB6, CeB6, PrB6 , NdB6, ErB6, ThB6, YbB6. Considering, that neither the structure nor the interatomic connections within the temperature search of hexaborides does not change, the value of the parameter γ is determined. Its value was obtained within 2.5–4.7 for CeB6, NdB6, ErB6, YbB6, ThB6 and order 5.5–6.6 for CaB6, YB6, LaB6, PrB6. The parameters of Gruneisen proved to be practically independent of temperature. The presence of the meanings of γ made it possible to divide the implicit and explicit parts of the anagrammonism into a calming measure. The generalizing measure of anharmonism is mainly exhausted by the product γβ (β – the coefficient of the volumetric expansion of the crystalline lattice.
KEPUASAN MASYARAKAT TERHADAP KUALITAS PELAYANAN PUSKESMAS SANANWETAN KOTA BLITAR
Authors: Irtanto Irtanto
Published: November 2018

Penyelenggaraan pelayanan publik haruslah dimaknai sebagai sebuah usaha untuk pemenuhan hak-hak dasar masyarakat dan merupakan kewajiban pemerintah untuk melakukan pemenuhan hak-hak dasar tersebut. Pengaduan masyarakat adalah hal penting yang harus disikapi, karena mereka yang mengetahui dan merasakan baik buruknya pelayanan.
STRATEGI MENINGKATKAN KEPUASAN DAN MENARIK INVESTOR DI JAWA TIMUR
Authors: Priyambodo Priyambodo
Published: November 2018

Kebijakan Pemerintahan Daerah untuk menaikan Pendapatan Asli Daerah (PAD) bisa berakibat kontra produktif karena yang terjadi bukan PAD yang meningkat, akan tetapi justru mendorong para pengusaha memindahkan lokasi usahanya ke daerah lain yang lebih menjanjikan. Pemerintah haru berhati-hati dalam mengeluarkan Peraturan Daerah tentang pajak, dan jangan smapai terjadi ekonomi biaya tinggi akibat beban pajak yang terlalu tinggi.
PERAN SUMBERDAYA HUTAN TERHADAP KEPARIWISATAAN JAWA TIMUR *)
Authors: Sasongko Widodo Djati
Published: November 2018

Tujuan kajian : (1) Memahami peranan sumber daya hutan Taman Nasional Bromo Tengger Semeru (TN-BTS) dan kepariwisataan di Jawa Timur; (2) Menghasilkan rekomendasi usulan strategi pengembangan TN-BTS untuk pemanfaatan kepariwisataan. Metode kajian deskriptif dengan pendekatan yang digunakan adalah kajian kualitatif dan analisannya kualitatif. Lokasi kajian di TN-BTS. Metode pengumpulan data dilakukan dengan 3 (tiga) teknik metode, yaitu : (1) wawancara, (2) Observasi, dan (3) dokumentasi dan literatur.sedangkan metode analisis menggunakan analisis SWOT dan analisis interaktif. Rekomendasi : (1) Memberi kesempatan kepada civil society turut mengembangkan zona pemanfaatan, melalui hubungan kemitraan yang bisa melibatkan organisasi internasional, nasional, lokal maupun pribadi-pribadi dengan balai TH-BTS, (2) Mendorong berdirinya pendidikan konservasi alam atau laboratorium konservasi alam di zona pemanfaatan yang dapat dikunjungi oleh para peminat pendidikan lingkungan hidup maupun para peminat kegiatan alam terbuka termasuk wisatawan, (3) Mempertahankan dan mengembangkan adat istiadat dan budaya masyarakat Tengger yang arif bijaksana, luhur dan positif, misalnya ajaran wewaton, aturan adat untuk tidak merusak hutan dan lingkungannya, sistem pemilikan tanah yang tidak boleh dijual atau dipindahkan ke masyarakat di luar masyarakat Tengger; (4) Pemanfaatan pariwisata TN-BTS sebagai kawasan wisata terbatas dengan menekankan pada kualitas. TN-BTS bukanlah lokasi kawasan wisata massal (non mass tourism), (5) Mengembangkan obyek dan daya tarik wisata kompleks Gn. Semeru dan kompleks Gn. Bromo menjadi kopleks pariwisata yang terpadu dan berkelanjutan yang berdampak pariwisata negatif rendah dan memiliki daya saing; (6) Melengkapi fasilitas yang dibutuhkan oleh wisatawan didaerah penyangga (buffer zone) yang menuju pintu masuk kawasan TN-BTS yang sesuai dengan skala kebutuhannya.
PROFIL KOMPETENSI GURU SMAN BERDASARKAN PP 19 TAHUN 2005 DI KOTA KEDIRI
Authors: Irtanto Irtanto
Published: November 2018

Guru profesional memiliki kualifikasi akademik minimal D4 atau S1 pada bidang studi yang sesuai dengan yang diajarkannya. Guru juga harus memiliki kompetensi yang meliputi profesional, pedagogik sosial dan personal.
EFEKTIVITAS PROMOSI BERSAMA DALAM MENINGKATKAN KEGIATAN EKONOMI DAERAH JAWA TIMUR
Authors: Djati Sasongko R. Widodo
Published: November 2018

Tujuan kajian ini adalah : (1) mengetahui atau memahami pelaksanaan program promosi bersama di tingkat pelaksanaan program efektif dalam meningkatkan kegiatan ekonomi Jawa Timur; (2) menyususn rekomendasi sbagai masukan rumusan kebijakan strategi promosi bersama agar dapat terpadu dan efektif dalam meningkatkan kegiatan ekonomi daerah di Jawa Timur. Penelitian ini trmasuk jenis penelitian evaluasi, pendekatan yang digunakan dalam penelitian ini kualitatif dan analisa kualitatif dengan metode penelitian deskriptif. Analisis data menggunakan analisisi interaktif dan Analitys Hierarchy Process (AHP) Aproach. Rekomendasi yang ditawarkan beberapa upaya yang seharusnya dilakukan oleh Pemerintah Daerah (propinsi, kabupaten dan kota) maupun swasta untuk efektivitas promosi bersama dalam meningkatkan kegiatan ekonomi daerah di Jawa Timur.
RETHINKING KEBIJAKAN POLITIK PENDIDIKAN NASIONAL DAN LOKAL
Authors: Mahfud Choirul
Published: November 2018

Belakangan ini, kajian politik dan pendidikan sangat ramai dibincangkan. Sebab, antara keduanya saling mempengaruhi. Salah satu wujudnya adalah berupa kebijakan politik pendidikan. Politik pendidikan membahas hal ihwal kebijakan pendidikan. Urgensi politik pendidikan di sebuah negara dan pemerintahan lokal sangat penting. Sama halnya dengan pentingnya kebijakan ekonomi dan kebijakan prioritas lain dalam suatu negara. Masalah pendidikan tidak mungkin dilepaskan dari masalah sosio-politik, karena kebijakan politik sangat menentukan arah pembinaan dan pengembangan pendidikan.
MODEL PENGEMBANGAN SISTEM PELAYANAN DENGAN MENGGUNAKAN CITIZEN’S CHARTER UNTUK MENINGKATKAN PELAYANAN YANG BERBASIS MASYARAKAT
Authors: Ratnawati Susi
Published: November 2018

Banyaknya keluhan dan pengaduan masyarakat, baik secara langsung maupun melalui media massa tentang rendahnya kualitas pelayanan publik yang diterima masyarakat menjadi salah satu indikator rendahnya kualitas penyelenggaraan pelayanan publik saat ini. Pelaksanaan Citizen;s Charter adalah suatu cara pendekatan pelayanan publik yang terbaik. Aspirasi masyarakat lebih bisa diakomodasikan, pelayanan yang diberikan menjadi lebih baik meski disisi lain diperlukan adanya dukungan teknologi untuk mempercepat dan mempermudah layanan, yaitu dengan penerapan Sistem Informasi Puskesmas (Sispusk) secara On-line.
STUDI PERENCANAAN PELAYANAN KESEHATAN KELUARGA MISKIN DI KABUPATEN MOJOKERTO
Authors: Sutomo Ibnu
Published: November 2018

“Program Kesehatan” tidak hanya menjadi milik, apalagi hanya ditandatangai oleh sektor kesehatan saja. Program kesehatan harus menjadi milik masyarakat, karena telah menjadi kebutuhan dasar. Program kesehatan harus dapat dilaksanakan masyarakat sendiri dengan kemandiriannya; advocasy , fasilitasi, dan technical assistant di bantu oleh multi sektoral termasuk masyarakat bisnis. Selain itu, di sektor kesehatan upaya yang dilakukan harus mampu lebih bersifat preventif dan promotif, tanpa meninggalkan upaya kuratif dan rehabilitatif. Dasar pandang dalam pembangunan seperti ini dikenal dengan paradigma sehat. “Pembangunan berwawasan kesehatan merupakan hak asasi manusia”. Pembangunan yang tidak mengindahkan dampak positif dan dampak negatif terhadap kesehatan manusia, lingkungan, sosial, dan budaya merupakan bentuk dari pelanggaran hak asasi manusia.
KELAYAKAN DAN PELUANG USAHA TANI ANGGUR DI KOTA PROBOLINGGO
Authors: Subagio Herman , Purnomo Sudarmadi
Published: November 2018

Minat para pengusaha/investor terhadap usaha tani anggur kurang karena belum jelas tentang usaha tani anggur terutama ketersediaan teknologi dan kelayakan usaha. Kelayakan usaha anggur dapat memberikan rata-rata keuntungan dari lebih 30 persen dalam 10 pohon anggur. Titik impas produksi usaha tani anggur adalah 6 kg/pohon, sedangkan titik impas harga (BEP) berkiasar Rp. 4.000,-/kg. Usaha tani anggur layak diusahakan dengan modal pinjaman secara komersial.
PENGEMBANGAN INSTITUSI DAN PENINGKATAN PELAYANAN PUBLIK
Authors: HT M Amir
Published: November 2018

Penelitian ini bertujuan mengidentifikasi institusi dan personil daerh dalam peningkatan pelayanan publik, dan tingkat kualitas pelayanan aparatur sesuai harapan masyarakat. Pengembangan institusi hanya merupakan wadah tempat untuk melaksanakan fungsi-fungsi kegiatan yang memang dibutuhkan dalam aktivitas pemerintahan, maka faktor-faktor yang mempengaruhi tingkat kapasitas kelembagaan pemerintah daerah dan pelayanan publik dapak disimak dalam dua aspek yakni : (a) faktor internal meliputi sumber daya manusia, sumber daya bukan manusia, perangkat lunak dan anggaran. (b) faktor eksternal meliputi lingkungan, kondisi masyarakat dan lain-lain.
PEMATAAN RAGAM SOSIAL KULTURAL MASYARAKAT DI JAWA TIMUR DALAM HUBUNGAN DENGAN PERUBAHAN SOSIAL BUDAYA DAN SOSIAL POLITIK
Authors: Irwantoro Irwantoro
Published: November 2018

Masyarakat Jawa Timur dibagi menjadi beberapa subkultur area besar antara lain masyarakat Jawa Mataram, Arek, Madura dan Osing, dimana masing-masing subkultur area mempunyai kelebihan dan kekurangan yang berdampak pada proses pembangunan. Proses pembangunan seyogyanya dapat mengembangkan nilai-nilai budaya agar pembangunan itu sendiri member manfaat yang maksimal bagi kehidupan masyarakat. Dengan demikian pembangunan harus menggunakan pendekatan yang memperhatikan aspek kultur masyarakat yang bersangkutan agar masyarakat dapat menikmati kemajuan tanpa kehilangan akar historis kulturnya.
REPOSISI DESA SEJUTA LONTAR BERDASARKAN ANALISIS SWOT
Authors: GS Ahcmad Daengs
Published: November 2018

Penelitian ini berfokus pada kegiatan ekonomi di pedesaan. Obyek penelitian adalah desa Hendro Sari Kecamatan Menganti Kabupaten Gresik. Penelitian ini menarik karena adanya potensi tanaman Lontar seluas kurang lebih delapan puluh hektar, yang ternyata dapat merupakan inspirasi sumber penghidupan bagi penduduk setempat. Hasil dari tanaman Lontar yang utama diunggulkan adalah minuman yang berasal dari deresan bunga Lontar. Minuman ini dapat menjadi dua bentuk atau jenis, yakni legen dan toak.
Banjir dan Pencemaran Kali Surabaya
Authors: Husein Ahmad
Published: November 2018

Peristiwa banjir kali Surabaya terjadi akibat kerja sistem daur intrologi yang tidak normal,karena distribusi air yang meresap ke dalam tanah (inlet) jauh lebih sedikit dibandingkan distribusi air yang keluar dan mengalir di atas permukaan tanah (outlet) untuk kebutuhan hidup manusia dan makhluk hidup lainnya. Jenid penelitian ini adalah penelitian terapan, karena hasil penelitian ini bersifat menjawab secara langsung masalah yang dihadapi masyarakat (Charters, 1925), yaitu Banjir dan Pencemaran Kali Surabaya. Tujuan penelitian ini adalah untuk mengetahui bagaimana proses terjadinya banjir dan pencemaran Kali Surabaya,factor-faktor penyebab dan solusi yang harus dilakukan agar kedua peristiwa tersebut segera dapat diatasi.
Experimental analysis of chemical demulsification of cutting oil
Authors: Pacholski Piotr , Sęk Jerzy
Published: November 2018

The wastewater produced by the metal industry is often present in the form of oil-in-water (O/W) or water-in- oil (W/O) emulsions. These fluids contain a certain amount of valuable oil that can be recovered in the recycling process. Therefore, the development of novel, efficient, and low cost processes for the treatment of metalworking fluid is necessary. Demulsification to separate oil/water mixtures is a very interesting option
because it allows the recovery and reuse of the lubricant oil and effects in cleaner, easily treatablemwastewater.Chemical destabilization is the most common way of demulsification of metalworking fluids. As an example, inorganic salts can be used as demulsifiers. In the presented work the efficiency of treatment of cutting emulsions with chemical demulsification with usage of aluminum sulfate (IV) is described. The emulsion
was prepared with Emulgol-ES12 self-emulsyfing oil delivered by Orlen S.A. In the research the feasibility of the demulsifier was checked.The novel in this paper is determination of the optimal dosage of emulsifier using the TurbiscanLab® apparatus. It is relatively quick and precise method that can be applied in the industry.
Assessment of environmental impact of agricultural biogas plants
Authors: Janas Monika , Zawadzka Alicja
Published: November 2018

Operation of biogas plants, anaerobic fermentation processes, collection and purification of biogas and its subsequent combustion may be a source of environmental hazard. The construction and operation of biogas plants is inextricably connected with the generation and emission of solid, liquid and gaseous pollutants into the environment. The aim of the work is to analyze environmental hazards resulting from the construction and operation of biogas plants. As part of the work, a comprehensive analysis of their impact on individual
components of the environment was made. The effect of biogas plants on atmospheric air, soil and water environment and acoustic climate was analyzed and the potential range of these impacts was presented.
Exploitation of a Multifunctional Twistable Wing Trailing-Edge for Performance Improvement of a Turboprop 90-Seats Regional Aircraft
Authors: Rea Francesco , Amoroso Francesco , Pecora Rosario , Moens Frederic
Published: November 2018

Modern transport aircraft wings have reached near-peak levels of energy-efficiency and there is still margin for further relevant improvements. A promising strategy for improving aircraft efficiency is to change the shape of the aircraft wing in flight in order to maximize its aerodynamic performance under all operative conditions. In the present work, this has been developed in the framework of the Clean Sky 2 (REG-IADP) European research project, where the authors focused on the design of a multifunctional twistable trailing-edge for a Natural Laminar Flow (NLF) wing. A multifunctional wing trailing-edge is used to improve aircraft performance during climb and off-design cruise conditions in response to variations in speed, altitude and other flight parameters. The investigation domain of the novel full-scale device covers 5.15 m along the wing span and the 10% of the local wing chord. Concerning the wing trailing-edge, the preliminary structural and kinematic design process of the actuation system is completely addressed: three rotary brushless motors (placed in root, central and tip sections) are required to activate the inner mechanisms enabling different trailing-edge morphing modes. The structural layout of the thin-walled closed-section composite trailing-edge represents a promising concept, meeting both the conflicting requirements of load-carrying capability and shape adaptivity. Actuation system performances and aeroelastic deformations, considering both operative aerodynamic and limit load conditions, prove the potential of the proposed structural concept to be energy efficient and lightweight for real aircraft implementation. Finally, the performance assessment of the outer natural laminar flow (NLF) wing retrofitted with the multifunctional trailing-edge is performed by high-fidelity aerodynamic analyses. For such an NLF wing, this device can improve airplane aerodynamic efficiency during high speed climb conditions.
Using Radio-Frequency Identification Technology to Measure Synchronised Ranging of Free-Range Laying Hens
Authors: Campbell Dana L.M. , Horton Brian J. , Hinch Geoff N.
Published: November 2018

Free-range laying hen systems provide individuals a choice between indoor and outdoor areas where range use may be socially influenced. This study used radio-frequency identification technology to track the ranging of individually-tagged hens housed in six experimental free-range pens from 28 to 38 weeks of age (46–50 hens/pen). All daily visits to the range were used to study group behaviour. Results showed that 67.6% (SD = 5.0%) of all hen movements through the pop-holes outdoors or indoors were following the movement of another hen (‘pop-hole-following’) compared to only 50.5% of movements in simulated random data. The percentage overlap in time that all combinations of hen pairs within each pen spent simultaneously outdoors or indoors showed a median value of overlap greater than the 90th percentile of random data. Pens housing hens that had been provided variable enrichments from 4 to 21 days (n = 3 pens) showed higher ‘pop-hole-following’ behaviour and a higher percentage of hen-pair association compared to hens reared in non-enriched conditions (n = 3 pens). These results show that birds in each free-range pen were primarily a cohesive flock and early enrichment improved this social cohesiveness. These results have implications for understanding free-range flock-level behaviour.
Towards a Fair, Rigorous and Transparent Fine Art Curriculum and Assessment Framework
Authors: Clarke Angela , Hulbert Shane , Summers Fleur
Published: November 2018

Assessing creative work is a complex issue in fine art education, particularly with the academy’s push toward the standardisation of assessment practices. This creates particular challenges for art educators such as defining creativity; balancing assessment of the person, the process and the outcome; identifying suitable assessment criteria; moderating subjective responses of assessors; providing feedback that does not inhibit future risk-taking, experimentation and creativity; and considering assessment for, as and of learning. This paper reports on a five-year curriculum and assessment project in the fine art undergraduate degree within an Australian university. The project was designed to provide greater clarity and transparency in the assessment of all aspects of creative and written works within the degree. Using case study and action learning methodologies, we found that assessing in fine art requires artistry and engaged dialogue. This dialogue must allow the language of the discipline to emerge and take into account the pedagogical purpose of assessment. When this process is systemically enacted across the curriculum of a program, assessment can move towards a fairer, more rigorous and transparent approach. We present a fine art curriculum and assessment framework that embeds the values of art educators and simultaneously acts within institutional requirements for assessment.
Intersection of Brain Development and Paediatric Diffuse Midline Gliomas: Potential Role of Microenvironment in Tumour Growth
Authors: Loveson Katie F. , Fillmore Helen L.
Published: November 2018

Diffuse intrinsic pontine glioma (DIPG) is a devastating and incurable paediatric brain tumour with a median overall survival of 9 months. Until recently, DIPGs were treated similarly to adult gliomas, but due to the advancement in molecular and imaging technologies, our understanding of these tumours has increased dramatically. While extensive research is being undertaken to determine the function of the molecular aberrations in DIPG, there are significant gaps in understanding the biology and the influence of the tumour microenvironment on DIPG growth, specifically in regards to the developing pons. The precise orchestration and co-ordination of the development of the brain, the most complex organ in the body, is still not fully understood. Herein, we present a brief overview of brainstem development, discuss the developing microenvironment in terms of DIPG growth, and provide a basis for the need for studies focused on bridging pontine development and DIPG microenvironment. Conducting investigations in the context of a developing brain will lead to a better understanding of the role of the tumour microenvironment and will help lead to identification of drivers of tumour growth and therapeutic resistance.
Moral Judgment: An Overlooked Deficient Domain in Multiple Sclerosis?
Authors: Ayache Samar S. , Chalah Moussa A.
Published: November 2018

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system through which patients can suffer from sensory, motor, cerebellar, emotional, and cognitive symptoms. Although cognitive and behavioral dysfunctions are frequently encountered in MS patients, they have previously received little attention. Among the most frequently impaired cognitive domains are attention, information processing speed, and working memory, which have been extensively addressed in this population. However, less emphasis has been placed on other domains like moral judgment. The latter is a complex cognitive sphere that implies the individuals’ ability to judge others’ actions and relies on numerous affective and cognitive processes. Moral cognition is crucial for healthy and adequate interpersonal relationships, and its alteration might have drastic impacts on patients’ quality of life. This work aims to analyze the studies that have addressed moral cognition in MS. Only three works have previously addressed moral judgement in this clinical population compared to healthy controls, and none included neuroimaging or physiological measures. Although scarce, the available data suggest a complex pattern of moral judgments that deviate from normal response. This finding was accompanied by socio-emotional and cognitive deficits. Only preliminary data are available on moral cognition in MS, and its neurobiological foundations are still needing to be explored. Future studies would benefit from combining moral cognitive measures with comprehensive neuropsychological batteries and neuroimaging/neurophysiological modalities (e.g., functional magnetic resonance imaging, tractography, evoked potentials, electroencephalography) aiming to decipher the neural underpinning of moral judgement deficits and subsequently conceive potential interventions in MS patients.
Layered Ternary and Quaternary Transition Metal Chalcogenide Based Catalysts for Water Splitting
Authors: Tiwari Anand P. , Novak Travis G. , Bu Xiuming , Ho Johnny C. , Jeon Seokwoo
Published: November 2018

Water splitting plays an important role in the electrochemical and photoelectrochemical conversion of energy devices. Electrochemical water splitting by the hydrogen evolution reaction (HER) is a straightforward route to producing hydrogen (H2), which requires an efficient electrocatalyst to minimize energy consumption. Recent advances have created a rapid rise in new electrocatalysts, particularly those based on non-precious metals. In this review, we present a comprehensive overview of the recent developments of ternary and quaternary 6d-group transition metal chalcogenides (TMCs) based electrocatalysts for water splitting, especially for HER. Detailed discussion is organized from binary to quaternary TMCs including, surface engineering, heterostructures, chalcogen substitutions and hierarchically structural design in TMCs. Moreover, emphasis is placed on future research scope and important challenges facing these electrocatalysts for further development in their performance towards water splitting.
Walking Ecosystems in Microbiome-Inspired Green Infrastructure: An Ecological Perspective on Enhancing Personal and Planetary Health
Authors: Robinson Jake M. , Mills Jacob G. , Breed Martin F.
Published: November 2018

Principles of ecology apply at myriad scales, including within the human body and the intertwined macro and microscopic ecosystems that we depend upon for survival. The conceptual principles of dysbiosis (‘life in distress’) also apply to different realms of life—our microbiome, the macro environment and the socioeconomic domain. Viewing the human body as a holobiont—a host plus billions of microbial organisms working symbiotically to form a functioning ecological unit—has the potential to enhance personal and planetary health. We discuss this ecological perspective in our paper. We also discuss the proposals to rewild the microbiome, innovative microbiome-inspired green infrastructure (MIGI) and the basis of prescribing ‘doses of nature’. Particular emphasis is given to MIGI—a collective term for the design and management of innovative living urban features that could potentially enhance public health via health-inducing microbial interactions. This concept builds upon the microbiome rewilding hypothesis. Mounting evidence points to the importance of microbial diversity in maintaining favorable health. Moreover, connecting with nature—both physically and psychologically–has been shown to enhance our health and wellbeing. However, we still need to understand the underlying mechanisms, and optimal types and levels of exposure. This paper adds to other recent calls for the inclusion of the environment-microbiome-health axis in nature–human health research. Recognizing that all forms of life—both the seen and the unseen—are in some way connected (ecologically, socially, evolutionarily), paves the way to valuing reciprocity in the nature–human relationship. It is with a holistic and symbiotic perspective that we can begin to integrate strategies and address connected issues of human and environmental health. The prospective strategies discussed in our paper focus on enhancing our connections with the natural world, and ultimately aim to help address the global challenge of halting and reversing dysbiosis in all its manifestations.
The Elephant in the Room: The Need for Increased Integrative Therapies in Conventional Medical Settings
Authors: Hall Missy , Bifano Susanne , Leibel Leigh , Golding Linda , Tsai Shiu-Lin
Published: November 2018

Pediatric integrative therapy programs are essential to the treatment and well-being of patients. Identifying an effective integrative therapy model within conventional pediatric medical settings, however, often proves difficult. Our goal in this article is to explore varied solutions to increase access and inclusion of integrative therapies in an effort to promote best practice and holistic care. The main methods applied in this article are vignettes that illustrate how the integrative therapies in a metropolitan academic hospital successfully treat the patient by complementing conventional medicine. This leads to comprehensive care. The central finding of the article proposes viable solutions to increase interdisciplinary collaboration both internally within the institution and externally. Integrative therapists detail how they were able to increase visibility and yield best practice through increased educational initiatives and interdisciplinary collaboration.