bluuebunny/crossref_metadata_2025 huggingface dataset:
Literatura y realidad: los cuentos de Después del terremoto de Murakami
Authors: Castellón Alcalá Heraclia
Published: December 2021

Este trabajo aborda cómo el motivo argumental del terremoto de Kobe se recoge en los seis cuentos del libro Después del terremoto, que Murakami escribió tras el impacto que este suceso causó en la sociedad japonesa y en él mismo. Se trata de comprobar la forma en que el suceso real aparece en estos cuentos que se encuadran en la narrativa de Murakami más vinculada a la realidad concreta, en la que elabora un retrato crítico de una época, un acontecimiento, un movimiento social. En cada relato se estudiará la presencia del componente realista, que refleja un cuadro dantesco, y cómo influye en las conductas de los personajes. Al mismo tiempo, ha de reconocerse la aparición del componente fantástico, que, si bien es antitético del anterior, es notoriamente significativo en los relatos murakamianos. El estudio permitirá observar que la causa del seísmo se atribuye –mediante el factor fantástico– a la acción de un mal encerrado en las honduras terrestres, pero sus efectos se tratan desde el plano de lo real.
Viajes y relatos de viajes. Variantes y nuevas posibilidades de un abordaje comparatista
Authors: Duplancic Elena
Published: December 2021

El presente trabajo considera las modalidades más recientes de viajes como experiencias antropológicas y sus correspondientes relatos. Se menciona brevemente el estado de la cuestión en cuanto a los estudios sobre dichos textos. Desde un punto de vista teórico, se analiza tanto el viaje como el viajero y se ofrecen algunos ejemplos prácticos. En relación con los relatos, se enumeran sus contenidos, sus intenciones y sus funciones. Se deja planteada la influencia de los avances tecnológicos vinculados con la experiencia del extranjero a la distancia, así como con la aparición de nuevas textualidades audiovisuales que compiten con el relato. Se destaca el rol del lector de la literatura de viajes, se plantea como viajeros obligados a migrantes y exiliados y se señala a los periodistas como autores privilegiados de relatos de viajes.
Laser-Profilsensor zur Überwachung hochwertiger gespreizter UD-Faserbänder aus Kohlenstofffasern
Authors: Weser Thomas
Published: December 2021

Faserkunststoffverbunde (FKV) sind mit ihren sehr guten gewichtspezifischen Festigkeiten und Steifigkeiten vor allem für Leichtbauanwendungen und zur Reduzierung bewegter Massen von großer Bedeutung. Durch die gezielte Ausnutzung von Konstruktionsfreiheitsgraden bei der Bauteilauslegung können kraftflussgerechte Strukturen entwickelt werden, die neben Merkmalen des Materialleichtbaus auch Aspekte des Formleichtbaus aufweisen. Für die Herstellung von FVK sind Kohlenstofffasern (CF) mit ihren spezifischen Eigenschaften sehr gut geeignet. Die High-Performance-Fasern lassen sich allerdings nur mit energieintensiven Verfahren fertigen, sind damit im Vergleich zu Konstruktionswerkstoffen wie Stahl und Aluminium teuer und müssen deshalb materialeffizient eingesetzt werden. Bei der Verarbeitung von CF zu Verstärkungsstrukturen für FKV haben sich die Multiaxialwirkmaschinen der Karl Mayer Technische Textilien GmbH, Chemnitz, fest etabliert.
L‘Oréal stellt seinen Deutschland-Vertrieb neu auf
Authors: Brändlein Philip
Published: December 2021

Der Kosmetikkonzern L’Oréal stellt seinen Vertrieb für den deutschen Lebensmitteleinzelhandel neu auf. Nach drei Jahren an der Spitze wechselt Benjamin Rachow innerhalb des Konzerns nach Vietnam. Mit Christian Wirtz übernimmt sein bisheriger Stellvertreter künftig die Verhandlungen.
Hype bei SB-Brot ist erstmal vorbei
Authors: Krost Heidrun
Published: December 2021

Aufbackbrötchen und Snacks spülen dem Handel Geld in die Kassen. Sie stehen für 3,5 Prozent Mehrumsatz bei Brot- und Backwaren jedoch aufgrund von Preissteigerungen. Der Mengenschub des Vorjahres ist erstmal vorbei.
El Pozo investiert in Ibérico
Authors: Bender Ralf
Published: December 2021

Speziell für iberische Fleischwaren hat El Pozo einen Betrieb in Jabugo errichtet. Auch Innovationen sollen wichtiger werden.
Schokolade ohne Schuldgefühl
Authors: Bender Ralf
Published: December 2021

Mit zwei neu entwickelten Markenkonzepten will der Schokoladehersteller Casa Grande dem Zeitgeist entgegenkommen.
„Die Sojabohne ist gekommen, um zu bleiben“
Authors: Behme Dagmar
Published: December 2021

Züchtungsfortschritt ist ein Motor für den deutschen Sojaanbau. Stjepan Spretnjak, Produktmanager bei der I.G. Pflanzenzucht, rechnet mit einer schnell wachsenden Fläche.
Barrierefreies Bauen - Funktions- und Konstruktionsmängel.
Authors: Metlitzky Nadine , Engelhardt Lutz
Published: December 2021

Die jüngste Novellierung des Behindertengleichstellungsgesetzes des Bundes rückt das Barrierefreie Bauen wieder verstärkt in den Fokus. Welche Anforderungen dabei zu erfüllen sind, gibt die Normenreihe DIN 18040 vor. Die Norm beschreibt anhand von Schutzzielen, welche Eigenschaften Gebäude besitzen müssen, um Menschen mit Behinderungen Zugang und Nutzung zu erleichtern. In der Praxis hat sich herausgestellt, dass diese Ziele technische Detaillösungen erfordern, die teilweise im Widerspruch zu den gültigen bautechnischen Normen stehen. Was im Neubau durch vorausschauendes Planen und Verwendung geeigneter Bauprodukte noch lösbar ist, bereitet im baulichen Bestand oft erhebliche Schwierigkeiten. Funktional und baukonstruktiv mangelhafte Ausführungen sind die Folge. In diesem Buch fassen die Autoren ihre langjährigen Erfahrungen beim Barrierefreien Bauen zusammen. Aus dem Blickwinkel der Sachverständigen schildern sie an bereits in Betrieb gegangenen Objekten und an nachgerüsteten baulichen Anlagen, was passiert, wenn das Gesamtthema der baulichen Barrierefreiheit ungenügend Berücksichtigung gefunden hat.

Das Buch gibt Fachplanern Hilfestellung, Fehler zu vermeiden, indem Konflikte zwischen der Forderung nach barrierefreier Planung und konstruktiv/bauphysikalischen Anforderungen erkannt und geeignete Sonderlösungen entwickelt werden. Zum anderen unterstützt das Buch Sachverständige darin, bei der Beurteilung von Mängeln und Schäden weitsichtig alle funktionalen und konstruktiven Aspekte zu erkennen und zu berücksichtigen.
ОБРАЗИ ЄВРОПЕЙСЬКОЇ ХУДОЖНЬОЇ ЛІТЕРАТУРИ В ДЗЕРКАЛІ ЕКСЛІБРИСУ
Authors: NESTERENKO Petro
Published: December 2021

Екслібрис є важливою складовою книжкової культури, щирим зізнанням книголюба в його відданій любові до книги. Образно-художня сутність українського книжкового знаку приваблює своєю багатогранністю. Враховуючи, що екслібрис – це охоронний знак книжки, найулюбленішим елементом композиції досить часто слугує саме вона, бо найбільше пасує до функціонального призначення книжкового знаку. Важливим стимулом для художників і власників екслібрисів були ювілейні дати, які привертали їхню увагу до літературного процесу не лише в Україні, а й у країнах Європи. Тому значна кількість екслібрисів була представлена досягненням не лише світочів українського народу, а й геніям усього людства, письменникам і їхнім літературним героям. Окрему групу формують численні книжкові знаки, присвячені особливо шанованим Тарасу Шевченку, Миколі Гоголю, Івану Франку, Лесі Українці. Сприяли появі екслібрисів, присвяченим відомим українським письменникам і поетам, ювілейні дати, які особливо широко відзначалися у ІІ пол. XX ст. Серед них 200-ті роковини Івана Котляревського (1969 р.), Григорія Квітки-Основ’яненка (1978 р.), 150-річчя Марка Вовчка (1984 р.), «Русалки Дністрової» (1987 р.), 800-річчя «Слова о полку Ігоревім» (1988 р.), 150-річчя Василя Стефаника (2021 р.) тощо. 

            У творчості художника Георгія Малакова туристична поїздка країнами Європи мала вирішальне значення для його неперевершених ілюстрацій та екслібрисів.

            «Божественна комедія» флорентійця Данте Аліг’єрі (1265-1321 рр.), «Декамерон» Джованні Бокаччо (1313-1375 рр.), герой середньовічного німецького та нідерландського фольклору Тіль Уленшпігель Шарля де Костера (1827-1879 рр.), майстри сатиричних романів Сервантес (1547-1616 рр.) і Рабле (пр. 1494-553 рр.) стали об’єктами творчості українських екслібрисистів.

            Трагедія «Гамлет», яку Шекспір (1564-1616 рр.) написав у 1601 р., а надрукував у 1603 р., набула особливої популярності серед його творів. Загальновідомим став вигук «Бідний Йорик!».

            Серед улюблених персонажів – і герої французького письменника та льотчика Антуана де Сент-Екзюпері (1900-               1944 рр.). Особливо популярним завдяки російському колекціонеру Миколі Яценку став «Маленький принц», який став рекордсменом по кількості створених екслібрисів.
PENGEMBANGAN APLIKASI E-VOTTING UNTUK PEMILIHAN KETUA OSIS BERBASIS ANDROID (STUDI KASUS: SMKN 1 KRAGILAN, KECAMATAN KRAGILAN, KABUPATEN. SERANG PROVINSI BANTEN)
Authors: Rodianto  , Aliyah Jannatun , M.D Irsyad
Published: December 2021

Penelitian ini bertujuan untuk mengembangkan aplikasi e-votting untuk pemilihan ketua osis berbasis android, di smkn 1 kragilan agar pemilihan ketua osis dapat berjalan dan tidak mengganggu pelajaran nantinya. Dengan adanya aplikasi e-votting ini dapat memudahkan para siswa. Votting sendiri dikenal dengan istilah electronicvotting atau lazim disebut dengan e-votting, metode penelitian yang digunakan dalam penelitian ini adalah pengembangan sistem, yaitu experimen untuk merancang bangun aplikasi e-votting dengan android studio. Aplikasi e-votting dikembangkan menggunakan berbasis android. Aplikasi e-votting dibangun dengan menggunakan java, sistem e-votting ini tidak terlepas dari kekurangan, diantaranya perubahan beberapa menu untuk mencegah cybercrime. Untuk pengembangan perangkat lunaknya penulis menggunakan model waterfal.
The effectiveness of manual manipulation versus the Activator Adjusting Instrument in the management of acute facet syndrome of the lumbar spine
Authors:   , Gillespie David McKenzie
Published: December 2021

The purpose of this study was to compare the relative effectiveness of manual manipulation versus the Activator Adjusting Instrument in the management of acute facet syndrome of the lumbar spine
Food Control in Uganda: Gaps and Opportunities in the Rice Value Chain
Authors: Namubiru Leatitiah , Male Denis , Byaruhanga Yusuf Byenkya
Published: December 2021

Food control defines activities, along the food supply chain, that provide consumer protection and ensure that all foods provided for human consumption are wholesome, conform to safety and quality requirements, and are accurately labelled as prescribed by law. This review analysed the capacity and performance of the existing food control system in Uganda, with specific focus on the rice value chain. This study targeted food safety laws, regulations and agreements to which Uganda is signatory for gaps in, and opportunities for improvement of food control along the rice value chain. The operational components of a food control system including inspection, testing, certification, enforcement, and surveillance controls along the rice value chain were investigated. The analysis established there is a significant threat to food safety due to outdated laws, uncoordinated regulatory framework, overlapping mandates, limited testing capacity, inadequate human resource, limited awareness of contaminants and lack of epidemiological data on food outbreaks along the rice value chain. Food control systems must strike a balance between food security, food safety, market access gains and protection of public health.
Schwannoma on Cervical Cervices (C2 & C3): A Case Report
Authors: Supriyandono Djoko , Wibowo Marjono Dwi
Published: December 2021

Background: Schwannoma is classified as a benign, encapsulated tumor, derived from the perineural cells which are classified as neural cell membranes. About 10% of Schwannomas has occurred in the head and neck and the incidence of Schwannoma arising from the Cervical C2 nerve roots is extremely rare.
Aims of study: This case report aims to provide a rare case report on Schwannoma located in cervical cervices (C2& C3).
Case presentation: A 37-year-old female patient with a lump in the left neck for 4 years ago, the first lump appeared as a larger (increasingly large 1×1 cm) marbles with no pain in the lump but over the past 4 months the patient felt his legs and arms are weak. Patients have a history of surgical removal of tumors in the back of the neckline by the end of 2016. At first, we estimated the lump that appeared on the left neck of the patient stands alone in the sense that it was not related to the history of the first lump surgery, but when further examination, the tumor was apparently related to the lump that appeared previously who had surgery.
Conclusion: The extracranial Schwannoma in the head and neck areas is a rare neoplasm. The extracranial Schwannoma case is a case that is difficult to diagnose, in addition to good clinical examination, imaging examination, such as CT scan and MRI are an indispensable way of ensuring the diagnosis of an extracranial Schwannoma.
A CRITICAL EVALUATION OF THE PERCEPTIONS OF ERRORS IN THE LITERATURE ON SECOND LANGUAGE ACQUISITION (SLA) RESEARCH AND HOW APPLIED LINGUISTS AND TEACHERS NEED TO RESPOND TO ERRORS OF SECOND LANGUAGE LEARNERS
Authors: Bonsu Emmanuel
Published: December 2021

Second language learners, in acquiring English as a second language, make errors based on their cognition of concepts. The perception of linguists and teachers about errors inform their approach to language research and pedagogies. Linguists and teachers who have negative attitudes towards errors consider them as deviations that need to be prevented at all costs, while others perceive the errors as innovation. Indeed, while deviations could be innovative and contribute immensely to the development of new varieties of languages, some deviations are clearly deficits that could influence the acquisition process leading, and language teachers need to respond to these deviations appropriately. Through a systematic review of literature, the article presents an evaluation of errors (deviations or innovation) and their pedagogical purposes for applied linguists and teachers. Keywords: Second Language, Errors, Deviations, Innovations, Pedagogical Purposes
SOCIAL CLASS, CONSUMPTION AND CONFLICTS: A QUALITATIVE RESEARCH ON CONSUMERS IN A WEST AFRICAN CHRISTIAN CONTEXT
Authors: Nassè Dr. Théophile Bindeouè , Fielmua Dr. Nicholas , Musah Dr. Halidu , Carbonell Nicolas , Marfo Dr. Samuel
Published: December 2021

The relationships between alcohol consumption and conflicts has been explored in several contexts. Little research has been conducted on the subject in Burkina Faso. The purpose of this research is to deeply investigate the relationship between social class and alcohol consumption on one hand, and alcohol consumption and household conflicts on the other in Burkina Faso where alcohol consumption is on the increase. This exploratory research is focused on the constructivist epistemological posture. A qualitative method research design is used to collect data from both primary and secondary sources for analysis. Semi-structured interview guide was used for data collection. The results show that social class moderates the relationship between alcohol consumption and conflicts, and a high relationship between alcohol consumption and household conflicts. The findings imply that there should be a rigorous segmentation and religious hyper-personalisation of the alcohol beverage market in order to meet the local Christian consumers’ core needs and real expectations.  
To the best of authors’ knowledge, this is an exploratory research in the West African Christianity context that shows the relationship between different social classes and alcohol consumption and conflicts.
 Keywords: Social class, Alcohol Consumption, Household Conflicts, Ouagadougou
DYNAMIC CAPABILITY AND SUSTAINABILITY OF SMES IN SOUTH-EAST NIGERIA: THE NEXUS
Authors: Okeke Patrick , Owulo Odey Joshua , Akaegbobi Grace
Published: December 2021

Dynamic capability (DC) is an ability that has helped big corporations navigate successfully through the ever-changing and competitive business environment. However, SMEs in the southeast of Nigeria seem not to have fully maximized the opportunities embedded in these practices, hence, the need to examine the dynamic capabilities SMEs in Southeast Nigeria need, to stay relevant and ahead of competitors. This study, therefore, looked at the concept of DC and those capabilities that could help SMEs stay afloat in the ever-changing business environment. The capabilities looked at include sensing, absorptive and adaptive capabilities. Others are innovative networking and integrative capabilities. The study further examined the micro-foundations of DC and the composition of SMEs in South East, Nigeria. To embellish the work, Dynamic Capability Theory (DCT) was used to anchor the work. Some studies were reviewed empirically. The study concluded that DC is one of the surest ways to ensure that SMEs compete favourably in the ever dynamic marketplace. Hence, it was recommended among other things that SMEs need not to be operating in isolation of what is happening in the global market, as what happens outside has an implication on what happens inside the organization, and as such, need to be alert through the application of DC principles.
 Keywords: Dynamic Capability, Sustainability, SMEs, South-East, Absorptive, Adaptive and Innovative Capability.
NILAI-NILAI BUDAYA DALAM LEGENDA SITI PAYUNG
Authors: Handayani Dila , Sitinjak Dedy Rahmad , Hardi Rini Salsa Bella
Published: December 2021

Penelitian ini  menggunakan pendekatan Antropologi sastra untuk mengkaji tentang nilai-nilai budaya yang tedapat dalam Legenda Siti Payung. Cerita Legenda Siti Payung merupakan cerita rakyat yang berasal dari masyarakat Melayu Kabupaten Batu Bara. Adapun teori yang digunakan dalam penelitian ini adalah teori yang dikemukakan oleh Djamaris  (1996:3) tentang nilai-nilai budaya. Penelitian ini menggunakan metode penelitian kualitatif dengan menggunakan metode analisis analisis deskriftif  maka bentuk hasil penelitian ini berbentuk deskripsi kata-kata. Adapun sumber data primer dalam penelitian ini diambil dari buku Antologi Cerita Rakyat Batu Bara tahun 2015. Dari hasil analisis cerita Legenda Siti Payung ditemukan 5 nilai budaya yaitu 1. Nilai budaya dalam hubungan manusia dengan Tuhan sikap berdoa 2. Nilai budaya dalam hubungan manusia dengan alam yaitu sikap menjaga lingkungan. 3. Nilai budaya dalam hubungan manusia dengan masyarakat yaitu sikap patriotis membela yang benar. 4. Nilai budaya dalam hubungan manusia dengan manusia lain yaitu sikap sopan dalam berkomunikasi menenangkan hati lawan bicaranya. , 5. Nilai budaya dalam hubungan manusia dengan diri sendiri yaitu kegigihan diri.
Yaws: The forgotten tropical skin disease
Authors: Md Alwi Nadiah , Muhamad Rosediani , Ishak Azlina , Wan Abdullah Wan Noor Hasbee
Published: December 2021

Yaws is a rare skin disease endemic to tropical countries caused by Treponema pertenue. It is highly infectious and spreads through physical contact. In Malaysia, it was presumably eradicated during the 1960s, with the last reported case published in 1985. Due to its rarity, the disease often goes unrecognised and misdiagnosed. Here, we report the case of a 5-year-old aboriginal boy diagnosed with secondary yaws who presented with fever and an incidental finding of chronic painless ulcerated nodules and plaques on his lower limbs and gluteal region. His diagnosis was confirmed serologically with a venereal disease research laboratory lab test and he was successfully treated with a single dose of intramuscular benzathine penicillin G. Primary care physicians should not ignore this disease since its early recognition and appropriate treatment is vital to its eradication, especially in high-risk communities.
O PAPEL DO FARMACÊUTICO NO PROCESSO DE HEMODIÁLISE
Authors: Araujo Adeilza Almeida Pinto , Santos Vanessa Jesus dos , Araújo Neto José Fernando de
Published: December 2021

A insuficiência renal crônica consiste em lesão renal e perda progressiva e irreversível da função dos rins. O paciente renal necessita de um procedimento chamado hemodiálise que retira do corpo as substâncias indesejáveis como toxinas, líquidos e sais minerais. Dessa forma, o presente estudo tem o objetivo de analisar a importância do farmacêutico no tratamento de hemodiálise. Para a elaboração do estudo, foi utilizado o método de pesquisa bibliográfica, sendo esta realizada por meio de livros e estudos de natureza científica, oriundos das seguintes bases de dados online: PubMed, Web of Science, Bireme e Scientific Electronic Library Online (SciELO). O estudo expôs acerca da insuficiência renal e processo da hemodiálise, abordou como a farmácia clínica auxilia no tratamento da hemodiálise, o demonstrou os benefícios da atenção farmacêutica ao paciente renal. Por fim, conclui-se que o farmacêutico tem um papel fundamental no tratamento de hemodiálise, prestando a atenção farmacêutica de forma segura e eficaz, garantindo a adesão ao tratamento e melhor qualidade de vida.
ATENÇÃO FARMACÊUTICA NO TRATAMENTO DE ACNE VULGARIS
Authors: Costa Yasmin Matias da , Lobo Lívia Cabral
Published: December 2021

Acne vulgaris (AV) é uma doença inflamatória crônica das glândulas sebáceas do folículo piloso. Envolvendo as glândulas sebáceas, é uma doença caracterizada por Acne, pápulas, pústulas, nódulos, cistos e cicatrizes. A incidência de AV na população é elevada, principalmente entre adolescentes, 85% dos jovens de 12 a 24 anos são afetados. Embora AV não seja uma ameaça física, esta doença de pele tem efeitos de longo alcance. Psicossocial, principalmente na adolescência, período de mudanças de aparência. A terapia medicamentosa tem se mostrado eficaz na solução dessa situação. Neste caso, o farmacêutico provou ser um fator chave na transmissão de informações relacionadas a doenças de pele, tratamentos e tratamentos prescritos, também trazendo recomendações sobre os cosméticos mais adequados.
A BASE DE CÁLCULO DO ICMS SOBRE AS BONIFICAÇÕES EM MERCADORIA NO ESTADO DE SÃO PAULO
Authors: Chaves Leonardo Anacleto
Published: December 2021

O Fisco Estadual exige o recolhimento de ICMS sobre as operações bonificadas, exigência esta inconstitucional. A natureza da bonificação é o abatimento dado sob a forma física da mercadoria. Relativamente à própria operação de saída do estabelecimento comercial, sendo incondicional, deve ser excluído da base de cálculo do ICMS o valor das mercadorias bonificadas, nos termos da Constituição Federal e Código Tributário Nacional, ao disporem que a base de cálculo do imposto corresponde ao valor da operação. No entanto, a Fazenda do Estado de São Paulo, inconstitucionalmente, passou a exigir o ICMS sobre as mercadorias bonificadas a partir da Decisão Normativa CAT 4, de 30/11/2000.
TECNOLOGIA E A FORMAÇÃO DE PROFESSORES UNIVERSITÁRIOS: DESAFIOS E PERSPECTIVAS
Authors: Barros Reviu
Published: December 2021

Este artigo tem por objetivo abordar questões quanto à formação de professores universitários, procurando contextualizar as tecnologias como um novo paradigma emergente na educação superior. Atualmente, a evolução causada pelas novas tecnologias da informação e comunicação (TICs) trouxe mudanças sociais significativas para a sociedade. Na esfera educacional não é diferente, do ensino básico ao superior passaram e passam por mudanças, por isso, a necessidade de acompanhar a evolução tecnológica para melhorar a aprendizagem, não aderindo à estagnação e ao obsoleto. Na modalidade qualitativa e no sentido de tratar dos desafios e perspectivas do docente no ensino superior frente às perspectivas inovadoras da tecnologia, o objetivo específico deste artigo é elencar alguns pressupostos no viés com a prática pedagógica do professor. Diante disso, surgiu a seguinte indagação: quais os desafios e perspectivas dos professores com o auxílio das tecnologias para melhorar a prática pedagógica e promover aprendizagem no século XXI? Sob essa égide, este trabalho irá se debruçar com o enfoque na educação, principalmente no ensino superior, para tentar achar resposta para a problemática dessa pesquisa e contribuir para melhorar a prática pedagógica e por fim, trazer aportes que possam corroborar para a pesquisa e a aprendizagem significativa dos alunos.
JARDIM ZOOLÓGICO DO RIO DE JANEIRO: HISTÓRICO E DIVULGAÇÃO PELA MÍDIA IMPRESSA
Authors: D`Almeida José Mario , D`Almeida Claudia Alves
Published: December 2021

Com o presente trabalho, objetivamos avaliar a divulgação científica do Jardim Zoológico do Rio de Janeiro (JZRJ), pela mídia impressa, no período de 1945 a 2017, enquanto instituição pública. As notícias publicadas sobre o JZRJ foram classificadas, arbitrariamente, em três áreas temáticas: Educação, pesquisa e entretenimento, sendo que esta última foi a que apresentou maior divulgação pelos jornais avaliados, o que nos leva a concluir que a importância científica e educacional do JZRJ não teve a devida abordagem e divulgação pela mídia impressa. Por conseguinte, torna-se importante ressaltar que os Zoológicos deveriam priorizar mais a conservação, a Educação Ambiental e a pesquisa científica, partindo da premissa de que, só para conhecer “bichos”, bastam os documentários exibidos pelas televisões.
ESTADO SECURITÁRIO, DIREITO PENAL DO INIMIGO E A SEGURANÇA COMO RAZÃO DE SER DO ESTADO
Authors: Brito Fernando Vidal
Published: December 2021

O punitivismo moderno e o estado constante de vigilância na sociedade moderna encontram raízes teóricas nas correntes punitivistas da jusfilosofia penal que acumula séculos de tradição. A noção do homem como lobo que é predador do homem é tradição antiga que influencia a corrente punitivista e defende que a razão fundamental do Estado é garantir a segurança daqueles que estão sobre a umbrela do Estado. Tal cenário levou a construção de um estado securitário no qual a segurança é o valor supremo, influenciando as relações pessoais e erguendo e derrubando governos, assim como auxiliando na construção do Direito Penal do Inimigo. O presente artigo buscará demonstrar as raízes desse contexto e como correntes naturalistas nefastas se fazem presentes por meio da construção de um inimigo a ser destruído.
Kepuasan Wisatawan : Tinjauan Terhadap Atraksi, Aktivitas, Amenitas dan Aksesibilitas Di Taman Nusa Bali
Authors: Dyah Palupiningtyas  , Heru Yulianto
Published: December 2021

This study aims to analyze and explain the influence of Attractions, Activities, Amenities, and Accessibility (4A) on tourist satisfaction at Taman Nusa Bali which is experiencing unfavorable conditions including a decrease in the level of tourist visits every year, besides that there are several conditions of tourism components that need to be improved. The sample used in the study was 100 respondents. The research data was processed by quantitative statistical analysis using multiple regression analysis to determine the effect of the independent variable on the dependent variable. The results of the regression analysis show that an increase in variable 4A will increase tourist satisfaction. The results of the multiple regression analysis test show a significant F value, the adjusted R2 square coefficient value of 0.604 indicates that all 4A variables have a significant effect on tourist satisfaction together with a close relationship of 60.4%. This shows that to increase tourist satisfaction it is necessary to increase all tourism components in order to increase tourist satisfaction in the next period.
Biotherapy of miceâ€™s serum 13cH modifies parasitological and immunological parameters of Trypanosoma cruzi infection.
Authors: Ferraz Fabiana Nabarro , Da Veiga Franciele Karina , Aleixo Denise Lessa , Da Silva Suelen Santos , Pavanelli Wander RogÃ©rio , De AraÃºjo Silvana Marques
Published: December 2021

Background: T. cruzi biotherapiesâ€™ alter the infection course by this protozoan [1,2], fact that encourages the evaluation of other highly diluted medicines which modulates hostâ€™s immune system. Aim: Evaluate effect of biotherapy produced from micesâ€™s serum in experimental infection by T. cruzi. Methodology: A blind, randomized and controlled study was performed. Animals: 60 male Swiss mice, four weeks old were inoculated intraperitoneally with 1400 trypomastigotes-Y strain and divided: MNI: mice non-infected by T. cruzi; IC: treated with hydroalcoholic solution 7%; BSI13cH: treated with miceâ€™s serum infected by T. cruzi 13cH. Biotherapies: produced from miceâ€™s serum infected by T. cruzi in 13cH dynamization [3]. Treatment: mice were treated 48 hours before and after infection. Subsequently animals were treated 56/56 hours until 9th day of infection (d.i). The medicine was diluted in water (1/100mL) and offered ad libitum, for 16 hours. Parasitological parameters: were evaluated pre-patent and patent period, parasitemia peak, total parasitemia and mortality [4]. Cytokine dosage: IL-4, IL-17, TNF-Î± and IFN-Î³ were measured in serum on 0, 8th and 12th d.i., by enzyme immunoassay. Ethics: study was approved by Ethics Committee for Experiments in Animals/UEM. Statistic: data were compared with Mann Whitney or Student t test, significance 5%. Results: BSI13cH showed tendency to increase total parasitemia (p=0.06) and parasitemia peak (p=0.05), with lower patent period (p=0.03) and higher mortality (p=0.03) compared to IC. In dosage of cytokines BSI13cH group showed on 0 d.i. a decrease in IL-17 (p = 0.02) and increased IL-4 (p = 0.01) compared to MNI (baseline value), probably caused by modulation of medication administration 48 hours before infection. IL-17 concentration didnâ€™t vary throughout the infection to BSI13cH, different IC that tended to decrease concentration of cytokine on 8th d.i. IL-4 increased significantly on 0 d.i. to BSI13cH, with subsequent return to baseline values. IC group didnâ€™t change significantly IL-4 value along the infection. IFN-Î³ concentration on 12th d.i. to BSI13cH was lower (p = 0.00) than IC, which increased this cytokine on 8th and 12th di. TNF-Î± concentration of BSI13cH followed the same evolution as IC, with an increase on 8th and 12th d.i. (Figure 1). The medicine seems initially promote Th2 response (IL-4), hindering the development of effective Th1 response (INF-Î³), causing an increase of parasitemia and animals' death. Conclusions: BSI13cH demonstrated effect in experimental infection by T. cruzi with increased parasitemia, animalsâ€™ premature death and modulated immune response differently of IC.
Homeopathy: a possible weapon against multidrug-resistant bacteria to antibiotics
Authors: Passeti TÃ¢nia Aguiar , Souza Ana Paula Macedo , Bissoli Leandro Ribeiro , Beltrame Registila Libania , Coelho CidÃ©lia Paula , Diniz Suzana
Published: December 2021

Background: The antimicrobial resistance is a genetic phenomenon, related to the existence of the gens restrained in microorganism that codify different biochemical mechanisms that obstruct the drugs actions. Some species present resistance widespread in all over the world, like the case of Staphylococcus aureus. This is one of the main bacteria that, in a period of time, has got multiple resistance against the antibiotics, and itâ€™s also, an important agent causative of the nosocomiais infections. The present report evaluated the action of the different homeopathic medicines about the growth of the bacteria Staphylococcus aureus and Staphylococcus aureus MRSA (Methicillin-resistant Staphylococcus aureus) â€œin vitroâ€. Methods: Doses of 150, 250 and 350 ÂµL of the homeopathic medicines Silicea, Hepar sulfor, Belladona, Arnica montana, Mercurio solubilis and nosode of Stafilococcus aureus, in the dynamism 6cH, 12cH e 30cH had been placed in 3mL culture liquid Mueller Hinton. It was added to this blend 10 ÂµL of a diluted bacterial solution 1/10, where of the solution in 0,5 of the Macfarley scale in 37Â°C, the growth in the tubes was evaluated in Spectrophotometric of 600 nm. Results: The results demonstrated that, for the Staphilococcus aureus, we have got significant bacteria inhibition in about 70 to 90% of the growth â€œin vitroâ€, provided by the homeopathic medicines Hepar sulfor in the dynamism of 30cH, Belladona in the dynamisms of 6cH and 30cH, in the Staphilococcus aureus nosode in the dynamisms 6cH and 30cH and Silicea in the dynamism of CH6, with regard to the control with alcohol 30%. The Staphilococcus aureus MRSA presented inhibition from 40% to 20% of the bacteria growth â€œin vitroâ€ related to the control with alcohol 30%, with the same medicines used before. Conclusion: We can conclude that the homeopathic medicines have an inhibitory action in the bacteria growth, including in bacteria resistance to the antibiotics. This information can suggest that a concerted action of antibiotics and homeopathic medicines, could improve the action of the antibiotics in the bacteria causative of infections in the biological tissues.
Highly diluted natural complex (M2) effects on leishmanias
Authors: Nascimento Katia Fialho , GonÃ§alves Jenifer Pendiuk , Baum MaurÃ­cio , Pritsch Izanara , Ribeiro Magda Clara Vieira da Costa , Castro Edilene AlcÃ¢ntara de , Oliveira Carolina Camargo de , Buchi Dorly de Freitas
Published: December 2021

Introduction: Leishmaniosis is regarded as a serious public health issue either by its magnitude, morbidity or mortality. Depending on Leishmania species disease ranges from cutaneous, which is relatively confined and controlled, until a progressive and fatal visceral disease [4]. In order to complete their lifecycle Leishmania undergo transformations in the vector digestive tract to get to metacyclic infective form [3,5]. Those include secretion of the â€œpromastigote secretory gelâ€ (PSG) that protect parasites from digestive enzymes. PSG acts on survival and colonization of parasites inside the vector, on transmission and infection development in mammals, and also facilitates and increases transmission [1,2]. Drugs used for leishmaniosis treatment show high toxicity and several side effects, leading patients to quit the treatment and consequently generating resistant strains. The search for new therapeutic approaches is considered a strategic research priority by the World Health Organization. Highly diluted natural products show efficacy in modifying immunological response by stimulating the immune system through macrophages activation, then favoring the organism in many pathological conditions. Aim: To assess the direct action of M2 treatment on promastigotes of different Leishmania species. Methods: 3x106 were cultured in the presence of 20% of M2 plus booster 1% doses every 24h for up to 96h at 25ÂºC in humidified incubator and then submitted to assays for determining mitochondrial activity by MTT (5mg/mL), cell proliferation trough cell counting on Neubauer chamber and rosettes formation (around PSG) by light microscopy. Results of 3 independent experiments were statistically analyzed using t-test. Results: M2 treatment changed mitochondrial metabolic activity in all tested Leishmania strains. L. amazonensis proliferation decreased after 96h treatment and likewise the rosettes formation (total, closed and open ones). Discussion: Our data show that Leishmania cultures treated with M2 present decreased number of rosettes and these rosettes may be slowing the production of PSG, that is typically synthesized by Leishmania during metacyclic infective phase. Rosettes are also a place for fusion between 2 or more leishmanias, a process that involves nuclear and kinetoplast genetic material exchange. Conclusion: M2 acts on L. amazonensis promastigote forms by reducing the total number of rosettes (the same for open and closed rosettes) that are related to infective form of promastigotes, which produce PSG while on rosettes. This result suggests that M2 treatment is capable of decreasing Leishmania infectivity. Although our results are preliminary, these changes open new perspectives for the disease treatment and/or prevention using M2.
Transmission of the effect of Mercurius corrosivus 30 CH on ï¡-amylase in cell free medium through water.
Authors: Sarkar Tandra , Konar Atheni , Chakraborty Indrani , Sukul Nirmal Chandra , Sukul Anirban , Chakravarty Rathin
Published: December 2021

Abstract

Background

Mercurius corrosivus 30CH promoted ï¡-amylase activity in a cell free medium invitro. ï¡-amylase causes hydrolysis of starch. The activity of the enzyme is measured in terms of the amount of maltose liberated due to breakdown of starch. In a number of experimental studies it has been demonstrated that the effect of homeopathic potency would be transmitted from one plant to another through water. Here one leaf of a pair of plants was dipped in water in a beaker. The two beakers were connected by a water filled polythene tube. The effect of treatment of one plant with homeopathic potency would be observed in the directly treated plant as well as the connected plant. Two groups of toads were kept in water in two different containers. The two containers were connected by a water filled polythene tube. The effect of treatment of one group of toads with homeopathic potency would be observed in both the directly treated group as well as the connected group.

Objectives

The purpose of the present study is to see whether the effect of Mercurius corrosivus 30 CH on ï¡-amylase in one test tube would be transmitted to another test tube connected with the former by water filled capillary tube.

Methods

Mercurius corrosivus 30 CH was diluted with distilled water (1:100). Two hard glass test tubes each containing ï¡-amylase were connected with a water filled capillary tube while one test tube received Mercurius corrosivus 30CH solution, the other only the control solution. The control solution consisted of equal amount of 90% ethanol diluted with water (1:100).There were two more test tubes, one containing same amount of distilled water instead of Mercurius corrosivus 30 CH solution and the other test tube the same amount of 90% ethanol (1:100) as in the control set. After 10 mins starch solution in Sodium acetate buffer was added to each test tube. The enzyme in each test tube was allowed to react with starch for 15 mins and then it was stopped by DNSA (Dinitro salicylic acid) solution .The activity of ï¡-amylase was measured by standard biochemical process. The breakdown product maltose in each test tube was quantified by a standard curve prepared by measuring the optical density of the maltose solution at 560 nm in a UV-VIS Spectrophotometer. This experiment was repeated 20 times.

Results

Activity of ï¡-amylase was expressed in terms of the amount of maltose liberated from breakdown of starch with standard errors in 15mins at a fixed temperature. The data were analyzed statistically using t-test. Mercurius corrosivus 30 CH enhanced the enzyme activity significantly in the directly treated test tube as well as the connected one (p
Homeopathic Medicines Influence Fungal Adhesion and Cellular Oxygen Metabolism of MDCK and MA104 Cell Lines
Authors: Holandino Carla , Veiga Venicio , Barbosa Gleyce Moreno , Monteiro Camila Siqueira , Galina Antonio , El-Bacha Tatiana , Couceiro JosÃ© Nelson , Dos Santos AndrÃ© Luis Souza
Published: December 2021

Background: Fungal and viral infections constitute a serious public health problem, because morbidity and mortality rates of these diseases have been increasing in the last decades [1,2]. The resistance to antifungal and antiviral agents [3,4] currently available in the pharmaceutical market motivates the development of new therapies, including complementary and alternative health practices [5,6]. In this context, our research group has deepened the knowledge about the therapeutic potential of homeopathy using different models [7-9]. Homeopathic medicines undergo a process of serial dilution whereby the final remedy contains extremely low amounts of the active substance, with pharmacological action, and, consequently, cannot be considered merely placebos [10]. Aims: In the present study, we evaluated the potential of two different homeopathic medicines, named Influenzinum RC (compounded with influenza A virus) and Candida albicans RC (compounded with Candida albicans yeasts), which are prepared according to Brazilian homeopathic procedures [11]. Methodology: The biotherapics (12x, 30x) were prepared from Candida albicans yeasts [7, 11] and from influenza A (H3N2) viruses [6,11]. The cellular parameters evaluated after biotherapic treatments were: cytotoxicity by MTT assay; PFK-1 activity; and maximum respiratory capacity. Results: Our results showed that Influenzinum RC did not cause cytotoxic effects but induced morphological alterations, increased (p < 0.05) mitochondrial respiration, and significantly modified (p < 0.05) PFK-1 activity of MDCK cells. Additionally, using high-resolution respirometry we could detect an increase in the maximum respiratory capacity when these cells were treated with Influenzinum RC, despite a well-preserved ultrastructure of their mitochondrial organelles. In contrast, when MA104 cells were treated with Candida albicans RC, a significant decrease in cellular respiratory capacity as well as in yeasts adhesion rate was detected. Conclusions: These results indicate that homeopathic medicines modify important cellular and metabolic aspects of mammalian cells and these alterations should be responsible for the therapeutic potential of these drugs.
Behavioral parameters evaluation after homeopathic Zincum metallicum treatment: a transgenerational study in mice
Authors: Monteiro da Silva Silvio Leite , Coelho Cideli de Paula , Soares Luana de Ramos , Cesar Amarilys de Toledo , Bernardi Maria Martha , Holandino Carla , Bellavite Paolo , Bonamin Leoni Villano
Published: December 2021

Background: ZINCUM METALLICUM (ZM) is a homeopathic medicine whose materia medica is defined by diverse behavioral and mental symptoms, including depression. Moreover, as a microelement, zinc itself is involved in several functions of Central Nervous System, including development and cell maturity during the intra-uterus life. Aims: Herein, the putative transgenerational effects of different homeopathic potencies of ZM upon behavioral parameters in P and F1 generations were evaluated. Methodology: Since mice and the tail suspension test (TST) are references for evaluating antidepressant agent activity, the TST together with the open field test (OPT) and the elevated plus maze test (EPM) were used to analyze offspring behavioral parameters. All animal procedures were in agreement with the Brazilian ethical research practices and were approved by the institutional ethical committee (CEUA-UNIP) under the protocol 156/2013. Four groups of seven females Balb/C mice were exposed to 0,1mL of ZM 5cH, 30cH, 200cH and lactose 5cH, diluted in 250mL of drinking water, during pregnancy and post partum period, in a total of 31 days. The flasks were coded before the remedies administration and all experimental procedures, including statistical analysis were done in blind. The parents were previously distributed in a Completely Randomized Design for the mates, according to the TST previous results. Mothers were re-evaluated for TST after weaning and mice of F1 generation were evaluated for TST, EPM and OPT when they reached two months old. According to the time of immobilization in TST, animals were classified as healthy (h), intermediate (i) and depressed (d) (< 116; 117-180 and >180 seconds of immobilization, respectively). Results: No significant changes were seen among the groups regarding to the number of newborns, sex proportions, TST, OPT and EPM behavioral parameters, besides the fact that the treatment with ZM 200cH was associated to the majority of healthy F1 mice (male: n=8: 7h+1i+0d; female: n=8: 8h+0i+0d), in relation to the number of delivery per group (Fisher test, p â‰¤ 0.01). Treatment with ZM 5cH, instead, produced reduced number of pups with no male mouse among F1 generation. We conclude that the treatment of pregnant females with ZM 200cH produced the best results in F1 generation regarding reproduction and behavioral parameters and the treatment with ZM 5cH reduced births in relation to control. The involved mechanisms have to be elucidated in the next steps of the study.
Foundation of concept of constitutional homeopathic remedy by using electropuncture methods
Authors: Akaeva Tatiana , Mkhitaryan Karen
Published: December 2021

The work is dedicated to the issue concerning the foundation of the concept of constitutional homeopathic remedy in homeopathy and informational medicine by using the methods of vegetative resonance test and bioresonance therapy (VRT-BRT), using high signal mineral elements. In order to objectivize the mentioned concept, are identified three possible approaches. Are proposed the criteria of selection of the constitutional homeopathic preparation - VRT. Is presented the statistic equivalence, the validity and the clinical efficiency of these criteria.
Optimization of coprological studies in animals with the use of homeopathic Nux vomica 6CH
Authors: Drozdov Vladimir V
Published: December 2021

Background: Etiology of various gastrointestinal dysfunctions varies from infections and infestations to consequences of emotional stress and errors in animalsâ€™ nutrition. Taking this variability of etiology and pathogenesis into account, a lot depends not only on completeness of homeopathic history taking but also on the quality of laboratory studies. In our experience, coprology studies are especially complicated when persistent gastrointestinal disorders were preceded by massive use of allopathic remedies. This sometimes necessitates repeated examinations. That is why our interest in having reliable results and early detection of latent indigestion made us look for non-invasive methods which could be easy to use in animals but at the same time could reveal latent gastrointestinal pathology in animals. Aims: The study was aimed to determine the effect of a homeopathic medication Nux Vomica 6CH on detection of latent gastrointestinal pathology in small domestic animals. Method: Coprology studies were performed simultaneously with the use of sedimentation method and Fulleborn method (modification of Scherbovich). Infestations were diagnosed and characteristics of patient digestion were recorded. Feces test detected: 1. Presence of endoparasites (helminths, protozoa and yeast-like structures); 2. State of intestinal microflora (presence of different species and their balance with each other); 3. Degree of food absorbency (presence or lack of undigested protein, carbohydrates and fat); 4. Presence of inedible inclusions; 5. Presence of cells (lymphocytes, erythrocytes, intestinal epithelium, tumor fragments). If animal feces tests were non-informative, then all medications (except vitally important) were discontinued and Nux Vomica 6CH twice a day twenty minutes prior to food intake was prescribed for 6 days (4 globules dissolved in 10 ml of water). Results: 4500 coprology tests were performed during 3 years in cats and dogs. About 10% of the total number of examined animals (449 patients) produced very little information about the state of gastrointestinal systems at the first examination. When these cases were analyzed, the following reasons were found: long-term use of strong drugs, significant weakening of body immune system. As a result diagnostic tests were of very little value. These animals were treated by Nux Vomica 6CH for 6 days and then repeated feces test was performed. This produced a more informative picture of the state of gastrointestinal system and enabled to determine etiology and pathogenesis of the animal condition and prescribe necessary treatment. Conclusion. In such a way, Nux Vomica 6CH homeopathic remedy promoted effective optimization of coprology studies in animals. The suggested scheme of use for Nux Vomica 6CH significantly improves feces test quality. This in turn reduces time needed to choose strategy and tactics of treatment of small domestic animals with different chronic diseases.