bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluación sensorial, análisis fisicoquímico y microbiológico de las gomitas de Badea (Passiflora quadrangularis) y mora (Morus alba L) provenientes de Malqui-Machay, con propiedades antioxidantes
Authors: Cañar Pineda Mishel Lisbeth , García Valladares Pamela Dayana , Rivera Toapanta Evelyn Andrea , Flores Ortega Ronny Adrian , Tapia Calvopiña Ivan Luis
Published: November 2024

El estilo de vida actual promueve una dieta pobre en nutrientes y antioxidantes, dominada por la comida rápida y procesada. Estos hábitos han provocado problemas de salud como desnutrición, obesidad y enfermedades crónicas degenerativas asociadas al estrés oxidativo. Ante este problema, la investigación se centró en elaborar gomitas con antioxidantes naturales para contribuir en la mejora de la calidad de vida de la población, por tal motivo se realizaron análisis fisicoquímicos, sensoriales y microbiológicos. Los resultados mostraron variaciones significativas entre los tratamientos en términos de pH, grados brix, diámetro, ancho, espesor, conductividad, densidad, acidez titulable, humedad, textura y polifenoles. El Tratamiento (T8), que contiene extracto de Arándano/18 g glucosa de maíz, obtuvo la mayor cantidad de antioxidantes 63,64 g/100 g, asimismo tuvo el mayor grado de aceptabilidad en la evaluación sensorial debido a su menor contenido de glucosa y mayor proporción de pulpa de arándano, test que se realizó a través de una escalada hedónica gráfica. En cuanto a los resultados microbiológicos de aerobios mesófilos, mohos, levaduras, coliformes totales y E. coli, se determinó que todos los tratamientos se encuentran dentro de los rangos establecidos por la Norma Técnica Ecuatoriana INEN 2217. Demostrando la viabilidad de desarrollar gomitas sanas y naturales que cumplan con la normativa vigente, ofreciendo una alternativa saludable para el mercado.
Reading intervention through art of reaching and engaging (ARE) approach for struggling learners of an elementary school
Authors: Sialongo Adelfa , Sevilla Leoniza
Published: November 2024

This study explores the impact of the "Art of Reaching and Engaging" (ARE) approach on the reading abilities of struggling Grade 3 learners at Tugop Muslim Elementary School. Due to the absence of a specialized reading teacher, a 40-day reading intervention program was implemented, incorporating activities like prayer, modeling, music, and rewards to foster a passion for reading. Using a one-group pretest-posttest design, significant improvements were observed in students’ reading performance after the intervention. This research demonstrates the effectiveness of the ARE approach in enhancing reading skills among young learners, promoting a love for reading through an engaging and supportive learning environment.
ANSIEDADE E DEPRESSÃO EM PACIENTES COM ESCLEROSE MÚLTIPLA: UMA REVISÃO INTEGRATIVA
Authors: Rodrigues Nara Cardoso , Silva Belly Hellen Gomes Alves da , Passos Hortência Mendes de Carvalho , Cavalcante Sabrina Aguiar , Reis Antonielly Campinho dos
Published: November 2024

A Esclerose Múltipla é uma doença degenerativa, crônica, desmielinizante, autoimune e neurodegenerativa, a qual afeta o Sistema Nervoso Central. Diante disso, a condição clínica culmina em sintomas incapacitantes irreversíveis, os quais a longo prazo estão relacionados ao desenvolvimento de doenças psíquicas como ansiedade e depressão
PERFIL EPIDEMIOLÓGICO DOS PACIENTES INTERNADOS POR TRANSTORNOS TIREOIDIANOS RELACIONADOS À DEFICIÊNCIA DE IODO NO ESTADO DO PIAUÍ
Authors: Nery Filho Denisarth Oliveira , Lima Marina Barbosa Coêlho de , Gama Cássio Emanuel Neiva , Silva Neto Walter Oliveira da , Andrade Anderson Wilbur Lopes
Published: November 2024

O iodo é essencial para a produção dos hormônios da tireoide, mas tanto a deficiência quanto o excesso podem levar a doenças, sendo a necessidade diária de iodo para a síntese dos hormônios tireoidianos de 150 microgramas. A glândula tireoide tem alguns mecanismos internos para manter a normalidade de sua função mesmo em casos de excesso de iodo, e também busca se adaptar quando há limitação ou deficiência na ingestão dietética de iodo.
ACESSIBILIDADE PARA PESSOAS SURDAS NA ÁREA DA SAÚDE: A INCLUSÃO COMO NECESSIDADE SOCIAL
Authors: Melo Amarildo de Lima , Souza Caroliny Medeiros de , Paula Jaiciele Portela de , Melo Maria do Livramento Lima de
Published: November 2024

Este estudo versa sobre as principais barreiras enfrentadas por pessoas surdas no contexto da saúde e da Libras como necessidade social. Metodologicamente, esta pesquisa é de natureza qualitativa e enquadra-se como documental, sendo elaborada a partir de análise das legislações e de trabalhos científicos que discutem a temática em questão. Para embasamento teórico usamos autores como: Carvalho (2004), Bersch (2006); Lima (2006); Sassaki (2006); Mazzota (2011). Os principais achados revelaram que para as pessoas surdas terem acesso aos serviços de saúde de forma inclusiva e que suas necessidades comunicacionais sejam respeitadas e atendidas adequadamente é necessário a implementação prática de medidas como a capacitação em Libras de profissionais de saúde e a disponibilização de intérpretes e tecnologias assistivas.
The Vamp in Danish Cinema of the 1910s as a Prototype of the “New Woman”
Authors: Smagina S. A.
Published: November 2024

The article is devoted to the image of a vamp in Danish films, evolving by the 1920s into the image of a new woman, which later on gained major popularity in German and Soviet films.Not so vast by modern standards, Danish cinema in the early 1910s had a marked impact on the development of imagery in the world film art. Without having the lead in amount of films brought to the European film market, it however succeeded in setting the style in the cup-and-saucer drama genre, starting the fashion for specifically Danish melodramas and film sensations, introducing the viewer to the “Danish kiss” and crafting the image of a “vamp”, which very soon evolved in the world cinema into that of a new woman, reflective of the most important changes in the socio-cultural and socio-political life. Thereafter all the finds of the Danish filmmakers would be picked up and developed by the German, Soviet and American cineastes.Danish films preyed on the controversial and taboo ground of human vices, sexuality and gender relationships, commonly responding to urgent and sensational issues. What the Russian pre-revolutionary press called “glamorization of the 20th century shame” actually refers to what filmmakers did taking advantage of sensational facts for framing thrillers. So, for example the Danish cinema enters the international film market with the hotly debated back then topic of “white slavery”.The paper analyzes the pictures introducing the image of a vamp (the cyclus of “white slaves”, “The Abyss”, “Dance of the Vampire”, “Witches” etc.) and makes a guess at how the acute social issue of sexual slavery under the influence of culture-historical circumstances had evolved in cinema into the ideological construct of “the new woman”.
The Impact of Sustainability Reporting on the Cost of Capital of the Iraqi-Listed Companies
Authors: Rawaa ghazi  , Rawaa ghazi  , Hossein Fakhari  , Yahya Kamyabi
Published: November 2024

Purpose: The cost of capital is a critical factor influencing investment decisions and company financing. Sustainability reporting also enhances the strategic and organizational legitimacy of companies. Therefore, it is expected that sustainability reporting can influence company legitimacy with enhancing trust of companies, their capital costs is reduced. Based on this premise, the objective of this research is to investigate the impact of sustainability reporting on the cost of capital of companies listed on the Iraq Stock Exchange. Method: for testing of hypothesis Data from 33 listed companies on the Iraq Stock Exchange during the company's period of 2012-2022 was collected and analyzed using a multiple linear regression approach with a combination of panel data analysis. Result: Our findings indicate that Iraqi firms experience higher costs of capital due to their weak implementation of sustainability reporting.  Conclusion: reporting on corporate sustainability activities can enhance reputation of companies and, by gaining legitimacy for the companies, their cost of capital is reduced.  Implication: These findings can inform policymakers about the need to strengthen requirements for sustainability reporting. Also help investor to form an optimal portfolio based on the policy of companies in compliance with the sustainability reporting.
Estimation of the shelf life of sweetened soft drinks based on microbiological and sensory analysis
Authors: Salazar Llorente Enrique , Cabanilla María , Arias-Toro Daniel , Medina Gabriela
Published: November 2024

In the present investigation, the shelf life of sweetened beverages was investigated through microbiological
and sensory analyses. An experimental design was employed, which included the variable of storage time.
This allowed for the identification of significant differences in the organoleptic and microbiological characteristics of the beverages.
Samples of the beverages were taken during their processing and evaluated over time, especially during the
pasteurization process at 85°C for 120 seconds. Laboratory analyses focused on microbiological tests, sensory
studies, and assessments of the processed product's quality.
The microbiological results remained within the limits established by INEN standards, with counts of mesophilic aerobes < 100 CFU/cm3, yeasts and molds < 50 CFU/cm3, total coliforms < 3 MPN/cm3, and fecal
coliforms < 3 MPN/cm3. Regarding sensory analysis, it was found that the beverages had a characteristic
aroma, a slightly yellow color, and a characteristic citrus flavor, making them highly acceptable to consumers.
Furthermore, the shelf life of the beverages was determined through accelerated aging at 32°C, resulting in a
shelf life of 2 months. These findings supported the conclusion that the beverages could be stored for 6 months
at room temperature, as indicated in another study that employed a similar methodology and evaluated properties such as color, aroma, and flavor.
Keywords: Analysis, mesophilic aerobes, fecal coliforms, yeasts and fungi4
, shelf life.
In vitro evaluation of the inhibitory capacity of three Trichoderma isolates on Ralstonia
solanacearum
Authors: Pico Rosado Jimmy , Suárez Palacios Christopher , Jiménez Cumbicus Jessenia , Paredes Puga Ernesto , Sabando Gladys , Andrade Olalla Liliana
Published: November 2024

Bacterial wilt in bananas, caused by Ralstonia solanacearum or Moko, limits crop production and threatens
Ecuador. This study evaluated Trichoderma isolates in laboratory conditions as an innovative alternative to
ensure sustainability in banana production. The four R. solanacearum. isolates were obtained from banana
plants exhibiting disease symptoms and were characterized through morphological and biochemical tests. Four
treatments were evaluated: three isolates of fungi from the genus Trichoderma (Trichoderma viride, T. harzianum, T. asperellum) and one consisting of a combination of the three isolates above. The inhibitory capacity
of the Trichoderma isolates on R. solanacearum colonies was measured. A completely randomized design
with three replicates was used, and general linear and mixed models were employed, with qq-plot graphs for
normality and residual plots for variance homogeneity.
Furthermore, a Fisher's LSD test was conducted at a significance level of α = 0.05. In the biochemical tests,
the bacterial isolates exhibited specific characteristics of R. solanacearum in two bacterial isolates. In the
inhibition tests, treatment four and treatment one (consortium of the three Trichoderma isolates and Trichoderma viride) showed the highest inhibitory potential, with 76.07% and 61.19%, respectively. The consortium
of Trichoderma isolates demonstrated the highest inhibitory potential against R. solanacearum, with day 10
being the time with the highest percentage of inhibition (72.61%).
Keywords: Bacterial wilt, Ralstonia solanacearum, Trichoderma, inhibition
Based on Improved Lightweight YOLOv8 for Vehicle Detection
Authors: Zhou Jie , Xu Hongwei , Zhou Runjing , Du Xin
Published: November 2024

In urban road traffic, vehicle detection in intelligent transportation system can effectively
improve road traffic operation efficiency and road safety. Based on this goal, this paper is based on
the YOLOv8 framework, using the improved lightweight YOLOv8 model to realize vehicle detection,
the method replaces the Backbone network in the YOLOv8n model with a more efficient and
lightweight EfficientViT network, and further adds the CBAM attention mechanism in Neck to
enhance the detection precision, and later, Conv is replaced with the GhostConv model in Head to
reduce the number of parameters and increase the speed of detection. This model greatly improves
the detection precision and efficiency. We validate our approach on the UA-DETRAC vehicle
detection dataset, and the experimental results show that the proposed detection model Precision
reaches 91.17%, mAP@0.5 reaches 75.45%, and Recall reaches about 70.01%. Compared with
the original YOLOv8n model, Precision improves by 4.6%, mAP@0.5 improves by about 4.3%, and
Recall improves by about 9.1%. Through experimental validation, the model performs well in
detecting various complex road traffic scenarios, and this innovative approach can provide strong
support for the development of intelligent transportation systems, such as deployed on devices with
limited mobile hardware resources, and is expected to make further breakthroughs in future
applications.
An Exploration of Design Strategies for Public-Oriented Scientific Visualization Communication
Authors: Shang Shenhao
Published: November 2024

With the development of society, the public's attention and participation in science have
been increasing, driving the evolution of scientific visualization representation forms. Scientific
visualization has begun to have commodity attributes, and life science has become the key element
and focus of scientific visualization creation. This study starts from the perspective of new media
era communication design, and clarifies the concept and creative logic of scientific visualization
through literature survey. The basic elements of creation are extracted. Through case analysis of
the narrative methods and visual expression adopted in different scenarios of visualization design,
the key points of scientific visualization creation from the perspective of communication design are
summarized. Scientific visualization design has diversified development around different design
orientations for target audiences in different scenarios. Scientists pay attention to the precision of
visualization, while the public cares about the visual aesthetics and emotional response of
visualization design. At this time, when communicators create for the public, they need to
preconstruct an interesting story mode, adopt visual symbols familiar to the public, use modern
media communication platforms, and such design models are more likely to be favored by the
public
Tracking Employee Lifetime Value: Strategically Leveraging Metrics to Grow Your Talent Pipeline and Bottom Line
Authors: Westover Jonathan
Published: November 2024

This practitioner-oriented research brief examines why and how companies can strategically track employee lifetime value (ELV) metrics. ELV refers to the total financial contributions and indirect cost savings an employee provides over their career both within and beyond their tenure at an organization. After outlining the scholarly foundation demonstrating ELV as a key driver of competitive advantage, productivity, revenue and firm performance, the brief delves into methods for quantifying ELV. Two primary components are contribution value from direct compensation and indirect support roles, as well as retention value from avoided replacement expenses and future referral potential. Examples are given of calculating ELV through estimating average tenure, forecasting contribution streams, incorporating various rates and modeling knowledge depreciation. The brief then analyzes how leveraging robust ELV insights supports strategic decisions around talent deployment, succession planning, training investments, and evaluating alignment of strategies to sustain ELV. Finally, real-world case studies from the technology and financial services industries demonstrate multi-billion dollar impacts achieved by companies that proactively track and maximize employee lifetime value through workforce planning and positive engagement of employee networks.
IMPACT OF SELECTED MACROECONOMIC VARIABLES ON FOREIGN RESERVES IN NIGERIA
Authors: UMOLE I. MOHAMMAD  , SHAROMO DAUDA ARUNA
Published: November 2024

This study empirically examined the impact of selected macroeconomic variables on Nigeria’s foreign reserves. Quarterly time series data spanning from 1981Q1 to 2021Q4, covering both the pre-democracy 1981Q1 -19984 and democratic 1999Q1 -2021Q4 periods, were utilized for the analysis. The econometric model incorporates variables such as interest rate (INT), inflation rate (INF), exchange rate (EXR), oil export (OEP), non-oil export (NOE), and gross domestic product (GDP) as independent variables, with foreign reserves as the dependent variable. The ARDL bounds methodology for co-integration analysis was employed. The unit root test results indicate that most variables are stationary at the first difference, suggesting 1(1) integrations, except for the exchange rate (EXR), which is stationary at level 1(0). Co-integration analysis confirms long-run relationships between the macroeconomic variables and foreign reserves in both periods. The findings revealed that in the pre-democratic period, exchange rate, oil export, oil price, and non-oil export significantly impacted Nigeria's foreign reserves positively, while inflation rate had an inverse but insignificant effect in the long run. Similar results were observed in the democratic period, with the exchange rate, interest rate, and oil price impacted on Nigeria's foreign reserves. In conclusion, the study underscores the significance of exchange rate, GDP, oil and non-oil exports, and oil price fluctuations as major determinants of Nigeria's foreign reserves in both pre-democratic and democratic periods. Based on the findings, the study recommends among others, the government and monetary authority should initiate macroeconomic policies like lowering interest rate to promote and encourage economic activities through increased investments which will improve Nigeria’s GDP to enhance the performance of the country's reserves.
Organ-on-Chip: The Advancing Microfluidic Technology For Theranostics
Authors:   Centre for Biomaterials, Cellular and Molecular Theranostics (CBCMT), Vellore Institute of Technology, Vellore, India, Raheem Ansheed
Published: November 2024

Organ-on-chip (OoC) technology represents a revolutionary advancement in in-vitro modeling by closely mimicking the physiological and structural characteristics of human organs. It offers a significant improvement over existing microfluidic technology by integrating cell culture within these systems. This integration allows OoCs to simulate organ-level functions on a miniaturized platform, where a microenvironment resembling that within tissue is created through the dynamic flow of fluids and interactions between different cell types. This has valuable applications in drug discovery, disease modeling, and personalized medicine. This review delves into the engineering principles behind OoC systems, with an emphasis on their operating principles, construction, key materials, and various theranostic applications, supplemented by case studies. Key examples, such as lung-on-chip, liver-on-chip, and multi-organ systems, are discussed to illustrate OoC’s potential in theranostics, particularly in drug testing and disease progression studies. While OoC models provide significant improvements over traditional in-vitro methods, their potential to replace preclinical animal testing is still under investigation. Despite its promise, OoC technology faces several challenges, including integration with sensors, reproducibility, scalability, long-term stability, and regulatory hurdles. This review also explores future trends and technological advancements needed for OoC technology to become a standard tool in biomedical research and clinical applications.
Patient Perception of Robotic Total Knee Arthroplasty: A Qualitative Study
Authors:   Saint Joseph’s University Medical Center, Hackensack Meridian School of Medicine at Seton Hall University, USA, Pierce Todd , Novack Thomas , Issa Kimona , Festa Anthony , McInerney Vincent , Scillia Anthony ,   Department of Orthopaedic Surgery, Paterson, New Jersey, United States
Published: November 2024

Introduction: Total knee arthroplasty (TKA) is one of the most commonly performed orthopedic surgeries. The goal of robotic-assisted technology is to optimize outcomes through preoperative planning, ensuring accuracy in component sizes and precision in bone cuts. There is a paucity of literature that addresses patient perceptions of this new technology. Therefore, the purpose of this study was to assess why patients choose to undergo robotic-assisted TKA. Methods: All patients who underwent robotic-assisted TKA between July 1, 2017, and December 31, 2018, were given a 12-question survey to complete. The final cohort consisted of 76 patients composed of 51 women and 25 men with a mean age of 71 years (range, 51–88 years). All de-identified data was evaluated and tabulated for assessment. Results: Eighty-three percent stated they would recommend undergoing robotic-assisted TKA as opposed to conventional TKA with 72% stating the main influencer in their decision was physician input. Fifty-seven percent stated they thought their components would be placed in a more optimal position using robotics. Sixty-two percent believed they would achieve better outcomes with robotic TKA as opposed to their conventional counterparts. Among outcome questions, 55% believed they would have less pain with robotic-assisted TKA. However, the majority of the cohort stated they would have no difference in length-of-stay or infection risk compared to manual TKA. Exactly 50% of patients stated there would be similar operating room time between robotic and manual TKA. Discussion: The vast majority of our cohort believed there were benefits in opting for robotic-assisted TKA. Future studies should evaluate how attitudes and beliefs may influence patient-reported satisfaction and outcomes in the long term.
Small-Molecule Modulators of Toll-Like Receptor Signaling and Their Clinical Applications
Authors:   Independent Researcher and Consultant, San Diego, California 92111, USA, Matsunaga Naoko
Published: November 2024

Toll-like receptors (TLRs) are pattern recognition receptors expressed in various immune cells on the cell surface or within endosomes. TLRs play a key role in the innate immune response by detecting pathogen-associated molecular patterns. TLRs also recognize damage-associated molecular patterns that are endogenous molecules produced from damaged or stressed cells. TLRs are involved in the pathogenesis of a variety of inflammatory, infectious, and autoimmune diseases. Moreover, TLRs regulate immune response in the tumor microenvironment. The pivotal role of TLRs in the pathophysiology of these diseases makes them attractive targets for the development of innovative therapy for these immune disorders and cancer as well as preventive measures, such as vaccination. Manipulating the TLR signaling pathway by a small-molecule drug is one of the promising approaches for the development of effective treatments that can be translated into a clinical setting. Small-molecule drugs are chemically synthesized and are more economically sustainable than biologics. This affordability makes the drugs more accessible to patients including those in developing countries. Besides, small-molecule drugs can be more stable and easier to administer. Their oral bioavailability and accessibility to cytosol are the distinct advantages over biologics. Nevertheless, only a limited number of small-molecule modulators have been developed due to the difficulty in finding appropriate drug ­candidates with acceptable selectivity, toxicity, and physicochemical profile. Here, we overview the pathophysiological roles of human TLRs and structural features to discuss the efforts, current promising ­opportunities, and challenges in developing small-­molecule modulators of TLRs.
Climate Activism and Social Change: A Critical Examination of Influence on Policy and Public Attitudes
Authors:   Wheatley Research Consultancy, Bagley, Minnesota, USA, Wheatley Mary
Published: November 2024

Climate activism has evolved into a pivotal force driving social change and influencing public policy worldwide. This article systematically examines how grassroots movements and global campaigns have mobilized public opinion and spurred legislative action on climate change. It delves into the historical context of climate activism, from its early days to the present, and evaluates its effectiveness in instigating policy reforms and shaping societal norms. By analyzing key campaigns and their impacts, the review identifies both the successes and the ongoing challenges faced by activists, including political resistance and public skepticism. The discussion extends to the criticism of various activist methods and the potential pathways for future activism to further influence environmental policy and promote sustainable societal transformations.
ENTRE A VERDADE E O CONFORTO: DESAFIOS ÉTICOS E HUMANÍSTICOS NA COMUNICAÇÃO DE MÁS NOTÍCIAS EM ONCOLOGIA E CUIDADOS PALIATIVOS
Authors: DE JESUS OLIVEIRA Pablo , DE ALENCAR Helena Côrtes , FARIAS SILVA Ana Beatriz , DA SILVA COSTA Luís Henrique
Published: November 2024

No contexto da oncologia e dos cuidados paliativos, a comunicação de diagnósticos e prognósticos severos é uma prática essencial, mas também complexa e emocionalmente desafiadora. Profissionais de saúde se encontram na delicada posição de transmitir informações que impactam profundamente a vida dos pacientes e suas famílias. A ética na comunicação de más notícias requer um equilíbrio entre a verdade e o conforto, considerando a vulnerabilidade dos envolvidos e a necessidade de um cuidado humanizado. Objetivo: Este estudo busca analisar os desafios éticos e humanísticos que envolvem a comunicação de más notícias em oncologia e cuidados paliativos tentando compreender como os profissionais podem conciliar a necessidade de transparência com a empatia e o respeito às limitações emocionais dos pacientes e familiares, sugerindo práticas de comunicação eficazes e humanizadas. Metodologia: Foi realizada uma revisão de literatura nas bases de dados SciELO, LILACS e PubMed, com critérios de inclusão que envolveram artigos publicados nos últimos 10 anos, em português sobre comunicação de más notícias, cuidados paliativos e ética na oncologia. Resultados e Discussão: A comunicação de más notícias em oncologia e cuidados paliativos é frequentemente marcada pela tensão entre o fornecimento de informações precisas e o cuidado com o impacto emocional dessas informações. Os estudos mostram que os pacientes e familiares tendem a valorizar a transparência, mas também requerem um ambiente de acolhimento e sensibilidade. Estratégias como o uso do protocolo SPIKES, que enfatiza etapas como a preparação do ambiente e a escuta ativa, mostraram-se eficazes para minimizar o sofrimento e estabelecer um diálogo empático. Além disso, o estudo identifica que o treinamento em comunicação empática ainda é insuficiente, apontando para a necessidade de desenvolvimento contínuo nessa área. Conclusão: A comunicação de más notícias em oncologia e cuidados paliativos exige dos profissionais de saúde um cuidado ético e humanístico, visando um equilíbrio entre verdade e conforto. A prática de uma comunicação acolhedora e empática pode auxiliar no processo de aceitação dos pacientes e de seus familiares, promovendo uma experiência de cuidado mais digna e respeitosa.
Solution of boundary value problems for the heat equation with a piecewise constant coefficient using the Fourier method
Authors: Koilyshov Umbetkul , Sadybekov Makhmud
Published: November 2024

This paper considers some initial boundary value problems for the heat equation in a bounded segment with a piecewise constant coefficient. Using the method of separation of variables, the problem under consideration is reduced to a spectral problem and  eigenvalues and eigenfunctions of the resulting spectral problem are found. It is shown that the system of eigenfunctions forms a Riesz basis. Next, we prove a theorem on the existence and uniqueness of solutions to the  initial-boundary value problems under consideration.
ANALYSIS OF MAUDHUIY'S TAFSIR METHOD: A THEMATIC APPROACH IN INTERPRETING THE QUR'AN
Authors: Lubis Nanang Ardiansyah , Milhan Milhan
Published: November 2024

Tafsir Maudhuiy method is a systematic approach in interpreting the Quran based on certain themes, which provides a more holistic and applicable understanding of Islamic teachings. This study describes the history, requirements, steps, analysis, and implications of this method, both in general and in Indonesia. The history of the development of Tafsir Maudhuiy method shows the contribution of figures such as Muhammad Abduh, Rashid Rida, and Quraish Shihab in its development and application. The requirements and steps include mastery of Arabic language, Quranic sciences, and high analytical skills to identify the main themes of the Quran. An analysis of the method highlights its superiority in addressing contemporary issues in Islamic society. The implications of applying this method include the possibility of developing more in-depth and applicable thematic studies, as well as practical guidance for Muslims in dealing with modern challenges. Future projections show a bright prospect with an increased understanding and application of the Tafsir Maudhuiy method in various contexts, although it requires in-depth knowledge and objectivity in the interpretation of the Quran
Exploration of Librarians' Assertive Behaviour in Improving Service Quality in the Digital Age
Authors: Mufti Zevira  , Sri Rohyanti Zulaikha
Published: November 2024

This article explores the assertive behaviour of librarians in an effort to improve service quality in the digital era. It is expected that librarians can adjust to the rapid development of technology and the increasingly complex demands of users. To face these challenges, assertive behaviour is required, which includes effective communication skills, the ability to express opinions assertively, and self-confidence. This research uses the literature study method to look at various scientific sources on assertive behaviour and its impact on library service quality. The results show that assertive behaviour helps create good interactions between librarians and users, increases user satisfaction with services, and supports the transformation of libraries towards digital-based services. It is hoped that this research will provide insights for librarians on how to develop assertive skills to improve the quality of services provided by digital libraries.
Hengerességi hibák elemzése nem hagyományosan megmunkált hengeres munkadaraboknál
Authors: Varga Gyula
Published: November 2024

The machined workpieces must meet certain geometric requirements. During the cutting process, due to certain effects of the WDMT (workpiece, device, machine, tool) system, errors may appear on the finished workpiece. By changing the technological parameters, errors can be reduced or occasionally eliminated. The purpose of this study was to analyze the cylindricity deviations. The cylindrical surface was not processed in the usual way, by turning on a rotating workpiece, but by milling of a stationary workpiece. The objective is to investigate the deviation of the workpiece in cylindricity by changing the technological parameters when using different cooling-lubrication methods. On the base of preliminary results, recommendations for the technological parameters are given.
Jól tárolható alternatív gázok minőségi paramétereinek meghatározása
Authors: Kumar Baibhaw , Voith Katalin , Nagy Gábor , Ferenczi Tibor , Krámer Gyula , Szamosi Zoltán
Published: November 2024

The aim of this research to determine how the different parameters influence the quality of the final product of alternative gases. The meaning of the alternative gases is a gas which released during heat treatment in inert atmosphere. We present a method which different kind of wooden spacies are heat treated to different heat treatment time but in a given temperature which was 320°C. The influence of the moisture content in the basic material also was examined and concluded.
Ívben futó vasúti kerékpár energiadisszipációs vizsgálata
Authors: M. Szűcs Máté , Zábori Zoltán
Published: November 2024

This study concerns the curve resistance analysis of a single railway wheelset running in a curve based on numerical dynamic simulation. The curve resistance can be computed by determining the creep/friction forces generated in the wheel-rail contact. The simplified model, decoupled from environmental effects, allows the evaluation of the feature of the curve resistance force as a function of the two parameters considered over the speed of the wheelset and the curve radius.
Motivators and Barriers to Physical Activity among Healthcare Providers in Karbala City
Authors: Al-Najafi Waleed Khalid , Talal Naeem Obaid , Alkelaby Hamid Hussein , Ali Rawnaq  Abdulrazzaq , Abd Alridha Taghreed , Nahidh Haider Kamil
Published: November 2024

Background: Physical inactivity is a major risk factor for non-communicable diseases and premature mortality. Promoting physical activity among healthcare professionals is important, yet little research has examined this population in Iraq.
Aim: to assess physical activity motivators and barriers to physical activity among health providers in Karbala City, Iraq.
Methods: A cross-sectional study was conducted among 800 healthcare professionals from selected hospitals and primary care centers in Karbala using validated questionnaires on physical activity (IPAQ), motivation (SMS-28), and barriers. Physical activity levels, motivations, and barriers were analyzed overall and by socio-demographics. 
Results: Approximately one-third (33.6%) were classified as physically inactive. No significant differences existed across gender, age groups, or type of healthcare staff. Key motivators were intrinsic factors like accomplishment, experience stimulation and knowledge. Top barriers were fear of injury, lack of skill, and social influences. 
Conclusion: High rates of physical inactivity among healthcare professionals highlight the need for targeted workplace strategies, leveraging intrinsic motivation and addressing barriers around skills, environment and safety concerns. Further research should explore causative factors and assess the impact of tailored interventions. Healthcare organizations play a pivotal role in prioritizing staff wellness to catalyze broader cultural shifts.
Keywords: Karbala, health providors, physical activity, motivators, barriers
Tendencias Globales del Liderazgo Transformacional en Empresas Modernas
Authors: Bravo-Bravo Idilia Fernanda , Herrera-Sánchez Maybelline Jaqueline
Published: November 2024

El artículo examina el papel del liderazgo transformacional en empresas modernas en un contexto de rápida evolución y competitividad global. Se propone revisar las tendencias emergentes de este estilo de liderazgo, centrado en la inspiración y motivación de los empleados, para enfrentar desafíos como la innovación, la inclusión y la adaptabilidad. La metodología se basa en un análisis exhaustivo de literatura científica de alta relevancia para identificar patrones y resultados clave sobre la aplicación del liderazgo transformacional en entornos empresariales cambiantes. Los resultados destacan la capacidad de este liderazgo para promover una cultura de creatividad, cohesión y resiliencia organizacional, además de facilitar la adaptación a nuevas tecnologías y modelos de negocio híbridos. La discusión subraya la importancia de métricas de desempeño y satisfacción laboral como indicadores de éxito, así como de estructuras de apoyo para gestionar el cambio. Se concluye que el liderazgo transformacional es un recurso estratégico que potencia la competitividad y sostenibilidad empresarial, siendo esencial para desarrollar capacidades de innovación y cohesión en un mercado global.
Anaplastic lymphoma kinase-negative primary systemic anaplastic large cell lymphoma mimicking a ruptured epidermal cyst of the scalp: a case report and literature review
Authors: Ahn Il Young , Bae Tae Hui , Kang Shin Hyuk , Woo Soo Hyun , Kim Woo Ju , Hong Min Eui , Kim Han Koo
Published: November 2024

The incidence of anaplastic large cell lymphoma is 0.25 cases per 100,000 people. It usually causes lymphadenopathy and B symptoms; however, diverse cutaneous manifestations can also be observed. We report a rare case of anaplastic large cell lymphoma of the scalp, which presented similarly to a ruptured epidermal cyst. A 77-year-old woman visited the outpatient clinic complaining of scalp masses that had appeared 2 months before. One week before her visit, she had undergone incision and drainage at a local clinic but showed no improvement. Before surgery, facial magnetic resonance imaging revealed two suspicious ruptured cystic masses. Surgical excision was performed with a 1-cm free margin from the soft mass. Histopathology confirmed anaplastic lymphoma kinase-negative anaplastic large cell lymphoma. After wide excision and skin grafting for wound reconstruction, followed by consultation with a hemato-oncologist and radiation oncologist, chemotherapy was planned to prevent recurrence. Differentiating anaplastic lymphoma kinase-negative anaplastic large cell lymphoma of the scalp from a ruptured epidermal cyst-like mass proved challenging. We recommend considering the possibility of anaplastic large cell lymphoma if an epidermal cyst-like mass does not respond to antibiotics or conventional dressing, as illustrated by our rare case.
Les temps du droit international : temporalité et histoire critique
Authors: Fuhrmann Rémi
Published: November 2024

Le présent article a pour vocation d’offrir des éclaircissements sur la manière dont le passé, le présent et, plus généralement, la temporalité peuvent être mobilisés dans l’écriture de l’histoire critique du droit international. En partant de certains débats méthodologiques ayant structuré le tournant historique du droit international, il tente de mettre en lumière la manière dont différents intérêts ou projets critiques amènent et supposent des mobilisations et des conceptions différentes du passé et du présent ainsi qu’un jonglage permanent entre continuité et discontinuité. Enfin, s’appuyant sur la doctrine du droit intertemporel, il y est également démontré que ces problématiques ne se limitent pas à l’écriture de l’histoire, mais qu’elles influent également sur la capacité du droit international à mettre fin ou à remédier aux injustices contemporaines héritées du passé.
MULTIMODAL MISMATCH RESPONSES IN MOUSE AUDITORY CORTEX
Authors: Solyga Magdalena , Keller Georg B
Published: November 2024

Our movements result in predictable sensory feedback that is often multimodal. Based on deviations between predictions and actual sensory input, primary sensory areas of cortex have been shown to compute sensorimotor prediction errors. How prediction errors in one sensory modality influence the computation of prediction errors in another modality is still unclear. To investigate multimodal prediction errors in mouse auditory cortex (ACx), we used a virtual environment to experimentally couple running to both self-generated auditory and visual feedback. Using two-photon microscopy, we first characterized responses of layer 2/3 (L2/3) neurons to sounds, visual stimuli, and running onsets and found responses to all three stimuli. Probing responses evoked by audiomotor mismatches, we found that they closely resemble visuomotor mismatch responses in visual cortex (V1). Finally, testing for cross modal influence on audiomotor mismatch responses by coupling both sound amplitude and visual flow speed to the speed of running, we found that audiomotor mismatch responses were amplified when paired with concurrent visuomotor mismatches. Our results demonstrate that multimodal and non-hierarchical interactions shape prediction error responses in cortical L2/3.
*** Dear reader, please note this manuscript is formatted in a standard submission format, and all statistical information is provided in Table S1. ***
k-Clique counting on large scale-graphs: a survey
Authors: Çalmaz Büşra , Ergenç Bostanoğlu Belgin
Published: November 2024

Clique counting is a crucial task in graph mining, as the count of cliques provides different insights across various domains, social and biological network analysis, community detection, recommendation systems, and fraud detection. Counting cliques is algorithmically challenging due to combinatorial explosion, especially for large datasets and larger clique sizes. There are comprehensive surveys and reviews on algorithms for counting subgraphs and triangles (three-clique), but there is a notable lack of reviews addressing k-clique counting algorithms for k > 3. This paper addresses this gap by reviewing clique counting algorithms designed to overcome this challenge. Also, a systematic analysis and comparison of exact and approximation techniques are provided by highlighting their advantages, disadvantages, and suitability for different contexts. It also presents a taxonomy of clique counting methodologies, covering approximate and exact methods and parallelization strategies. The paper aims to enhance understanding of this specific domain and guide future research of k-clique counting in large-scale graphs.
Nutritional and Bioactive Properties of Composite Flour Made from Hempseed and Corn Silk for Formulation of Fibre and Protein Rich Paratha
Authors: Raghuvanshi Rita Singh , Singh Diksha , Apurva
Published: November 2024

Aim: This study aims to analyze Nutritional and Bioactive properties of a novel composite flour and paratha made from it, developed by incorporating hemp seed flour, corn silk flour, and chickpea flour alongside wheat flour, targeting the creation of a high-protein and high-fiber flour blend for food product formulations.
Study Design:  A randomized experimental study was conducted to evaluate the functional and nutritional profile of the developed composite flour and paratha taking whole wheat flour as control.
Place and Duration of Study: Department of Food Science and Nutrition, G. B. Pant University of Agriculture and Technology, Pantnagar, between August 2019 to March 2023.
Methodology: Various ratios of hemp seed, corn silk, and chickpea flours were blended with whole wheat flour to make the composite flour. Paratha, a common shallow fried Indian flatbread, was prepared from the blend. Sensory evaluation of the paratha was conducted to find in addition to analyses of functional properties, proximate composition, dietary fiber content, in vitro protein digestibility, bioactive compounds, and fatty acid profiles of both flour blend and paratha.
Results: The composite flour demonstrated a higher water absorption capacity (179.63 ml/100g) than whole wheat flour (147.67 ml/100g). Proximate analysis revealed a crude protein content of 17.06% and crude fiber content of 7.81% in the composite flour, significantly exceeding than that of whole wheat flour. Total dietary fiber was recorded at 21.37 g/100g, with an in vitro protein digestibility of 76.70%. The total phenolic content was markedly higher in composite flour (223.51 mg GAE/100g) compared to whole wheat flour (49.82 mg GAE/100g). Sensory evaluation indicated that the parathas made from composite flour had acceptable taste and texture with superior nutritional profile.
Conclusion: The study successfully developed a composite flour with superior nutritional attributes, highlighting the potential of incorporating wild and underutilized plant resources in sustainable food production. This novel composite flour can be a valuable addition to diets, offering enhanced protein, fiber, and bioactive compounds compared to traditional wheat flour, particularly in the preparation of nutritious parathas.
Inhibition of Escherichia coli Cell-Free β-Galactosidase Activity by Binary Mixtures of Water-miscible Solvents
Authors: Opurum Christian C. , Mejeha Obioma K. , Nweke Christian O. , Nwangwu Oluchukwu R.
Published: November 2024

The inhibitory effects of ethanol-dimethylsulfoxide (DMSO) and ethanol-N,N-dimethylformamide (DMF) binary mixtures on the activity of cell-free β-galactosidase from Escherichia coli were assessed. The concentration-response relationships of the individual solvent and the mixtures were fitted to a Gormpertz model to estimate the median inhibitory concentrations (EC50) and No-Observable-Effect-Concentration (NOEC) thresholds. The EC50 values estimated are 29.246 ± 2.986% (ethanol), 28.112 ± 0.471% (DMSO), and 18.244 ± 0.674% (DMF). The NOEC values are 11.265 ± 1.121% (ethanol), 6.4047 ± 0.564% (DMSO), and 1.897 ± 0.427% (DMF). The order of inhibitory effects is DMF > DMSO > ethanol. The mixture NOEC values ranged from 10.081% (6:4 ethanol-DMSO mixture) to 13.619% (9:1 ethanol-DMSO mixture). In the case of ethanol-DMF mixtures, NOEC values ranged from 6.843% in 6:4 ethanol-DMF mixture to 10.599% in 9:1 ethanol-DMF mixture. All solvent mixtures with higher EC50 and NOEC values are less inhibitory than the individual DMSO and DMF. The inhibitory effects of the ethanol-DMSO and ethanol-DMF binary mixtures were predicted using the concentration addition (CA) model, toxic index (TI) and model deviation ratio (MDR). The TI for the ethanol-DMSO mixtures ranged from 1.076 ± 0.046 to 1.142 ± 0.032, while that of ethanol-DMF ranged from 1.027 ± 0.015 to 1.136 ± 0.024. These values are marginally higher than 1; thus, the combined effect is considered additive. The study provides fundamental information on the sub-inhibitory concentrations of ethanol, DMSO, and DMF, or their mixtures, for use in the permeabilization of E. coli cells for a β-galactosidase activity assay.