bluuebunny/crossref_metadata_2025 huggingface dataset:
The Global Hemostatic Thrombodynamics Assay in Healthy Children
Authors:   Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Russia, EA Seregina , MA Kumskova ,   National Medical Research Center of Hematology, Russia, MA Gracheva ,   Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Russia, AV Poletaev ,   Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Russia, KG Kopilov ,   National Medical Research Center of Hematology, Russia, FI Ataullakhanov ,   The Faculty of Biological and Medical Physics, Moscow Institute of Physics and Technology, Russia, NS Smetanina ,   Pirogov Russian National Research Medical University, Moscow, Russia, AN Balandina ,   Center for Theoretical Problems of Physicochemical Pharmacology RAS, Russia
Published: May 2021

Background: There is evidence that the concentrations of clotting and anticoagulant factors in children depend on age and differ from those found in adults. The results of APPT, TT, PT, fibrinogen are similar in children and adults in some studies, while PT and APTT show differences in others. Recent studies on global hemostatic assays Thromboelastography (TEG) revealed no significant differences in test results between healthy children and adults, while the thrombin generation test (TGT) showed significant differences. The Thrombodynamics (TD) assay is a new global hemostasis assay that considers the spatial organization of coagulation. Methods: APTT, TT, PR, fibrinogen and TD assays were performed in 102 healthy children between the ages of 1 and 17 years who underwent annual medical examinations and in 91 healthy adult volunteers. The following TD assay parameters were determined: lag time (Tlag), initial clot growth velocity (Vi), stationary clot growth velocity (Vs), clot size 30 minutes after the start of clot growth (CS) and clot Density (D). Written consent was obtained from all participants or their parents after they received complete information about the tests. Results: Age-specific reference values for the TD assay in healthy children aged 1-17 years are presented. No significant differences were observed between different age groups of children (15 years, 6-10 years, and 11-17 years) or between all children (1-17 years) and adults. Significant differences were not observed between genders. Conclusions: The TD assay results revealed no age-specific differences in the parameters between children aged 1-17 years and adults.
Total Syntheses of the C19 Diterpenoid Alkaloids (–)-Talatisamine, (–)-Liljestrandisine, and (–)-Liljestrandinine by a Fragment Coupling Approach
Authors: Wong Alice , Fastuca Nicholas , Mak Victor , Kerkovius Jeff , Stevenson Susan , Reisman Sarah
Published: May 2021

The C19 aconitine-type diterpenoid alkaloids (–)-talatisamine, (–)-liljestrandisine, and (–)-liljestrandinine have been prepared in 31, 30, and 33 steps, respectively, from phenol. The synthetic approach features a 1,2-addition/semi-pinacol rearrangement as the key fragment coupling tactic. These efforts have also resulted in a correction to the original structure assignment of (–)-liljestrandisine.
The Mechanism of Bending in Co-Crystals of Caffeine and 4-Chloro-3-Nitrobenzoic Acid
Authors: Thompson Amy J. , Price Jason , McMurtrie John , Clegg Jack
Published: May 2021

In a recent study, Dey et al.1 propose a mechanism of elastic bending in co-crystals of caffeine, 4-chloro-3-nitrobenzoic acid and methanol (1) in which mechanical interlocking is proposed to allow for the reversible flexibility observed. We have now determined the mechanism to atomic resolution using micro-focused synchrotron radiation,2 which is different to that previously reported. When subjected to strain the inter-molecular distances change and hydrogen-bonded dimers rotate over two orthogonal directions to allow the compression and expansion producing flexibility.
Self-sustained Marangoni Flows Driven by Chemical Reactions
Authors: Nguindjel Anne-Déborah C. , Korevaar Peter A.
Published: May 2021

Out-of-equilibrium chemical systems, comprising reaction networks and molecular self-assembly pathways, rely on the delivery of reagents. Rather than via external flow, diffusion or convection, we aim at self-sustained reagent delivery. Therefore, we explore how the coupling of Marangoni flow with chemical reactions can generate self-sustained flows, driven by said chemical reactions, and – in turn – sustained by the delivery of reagents for this reaction. We combine a photoacid generator with a pH-responsive surfactant, such that local UV exposure decreases the pH, increases the surface tension and triggers the emergence of a Marangoni flow. We study the impact of reagent concentrations and identify threshold conditions at which flow can emerge. Surprisingly, we unraveled an antagonistic influence of the reagents on key features of the flow such as interfacial velocity and duration, and rationalize these findings via a kinetic model. Our study displays the potential of reaction-driven flow to establish autonomous control in fuel delivery of out-of-equilibrium systems.
Quantitative Heterodimerization of Aromatic Peptides through Host-Enhanced Polar–π Interactions for On-Resin Recognition
Authors: Chen Xiaoyi , Huang Zehuan , Wu Guanglu , Sokłolowski Kamil , King Katherine , McCune Jade , Scherman Oren
Published: May 2021

Peptide dimerization plays an important role in both natural and artificial supramolecular systems. A major challenge to date is the quantitative heterodimerization of two peptides without formation of homodimers. Here, we employ a macrocyclic host to simultaneously encapsulate a canonical aromatic peptide and a non-canonical perfluorophenylalanine-containing peptide through polar–π interactions, thus forming an unprecedented new series of heteropeptide dimers with high binding affinity. This new peptide heterodimerization was applied to on-resin recognition and separation of aromatic peptides in a peptide mixture exhibiting over 95% isolation purity. This research unveils a generic approach to exploit quantitative heteropeptide dimers for the design of supramolecular (bio)systems.
The impact of binary water-CO2 isotherm models on the optimal performance of sorbent-based direct air capture processes.
Authors: Young John , García-Díez Enrique , Garcia Susana , van der Spek Mijndert
Published: May 2021

First, an investigation of the co-adsorption of water and CO2 onto a benchmark amine-functionalised adsorbent. Following on from this is a detailed process modelling and optimisation study of this sorbents performance in a direct air capture process. Next is a demonstration how the results are affected by the co-adsorption descriptions. Finally, a comparison between the modelled direct air capture process to existing and literature processes to benchmark the energy consumption of direct air capture.
Activating Room-Temperature Phosphorescence of Organic Luminophores via External Heavy-Atom Effect and Rigidity of Ionic Polymer Matrix
Authors: Ma Xiang , Yan Zi-Ang , Lin Xiaohan , Sun Siyu , Tian He
Published: May 2021

Pure organic room-temperature phosphorescence (RTP) materials have attracted wide attention for their easy preparation, low toxicity and applications in professional fields such as bioimaging and anti-counterfeiting. Developing phosphorescent systems with more universality and less difficulty in synthesis has long been the pursuit of materials scientists. By employing polymeric quaternary ammonium salt with an ionic bonding matrix and heavy atoms, commercial fluorescent dyes are directly endowed with phosphorescence emission. In a single amorphous polymer, the external heavy-atom effect generates excited triplet states, which are further stabilized by the rigid polymer matrix. This study proposed a new general strategy to design and develop pure organic RTP materials starting from the vast library of organic dyes without complicated chemical synthesis.
Biocatalytic Synthesis of Non-Standard Amino Acids by a Decarboxylative Aldol Reaction
Authors: Ellis Jonathan , Campbell Meghan , Kumar Prasanth , Bingman Craig , Buller Andrew , Geunes Eric
Published: May 2021

The formation of carbon-carbon bonds lies at the heart of organic chemistry, but relatively few C-C bond forming enzymes have found their way into the biocatalysis toolbox. We report that the enzyme UstD performs a highly selective decarboxylative aldol addition with diverse aldehyde substrates to make non-standard, γ-hydroxy amino acids. We increased the activity of UstD through three rounds of classic directed evolution and an additional round of computationally-guided engineering. The enzyme that emerged, UstD2.0, is very efficient in a whole-cell biocatalysis format and readily crystallizes. The X-ray crystal structure of UstD2.0 at 2.25 Å reveals the active site and empowers future studies. The utility of UstD2.0 was demonstrated via the stereoselective gram-scale syntheses of non-standard amino acids.
Synthesis of Twisted [N]Cycloparaphenylenes by Alkene Insertion
Authors: Terabayashi Tomoaki , Kayahara Eiichi , Mizuhata Yoshiyuki , Tokitoh Norihiro , Nishinaga Toru , Kato Tatsuhisa , Yamago Shigeru
Published: May 2021

This paper describes a new synthetic method of p-conjugated Mobius molecule by inserting an alkene or ortho-phenylene to cycloparaphenylenes. Physical properties of the obtained compounds were also studied.
Nitrogen-Substitution in the Flapping Wings of Cyclooctatetraene-Fused Molecules
Authors: Suga Kensuke , Yamakado Takuya , Saito Shohei
Published: May 2021

New synthetic protocols to the nitrogen-embedded flapping molecules have been developed. Gram-scale synthesis of a key precursor, tetraamine of dibenzo[a,e]cyclooctatetraene has been established for designing flapping quinoxaline and flapping phenazineimide. The impact of the nitrogen substitution on the photophysical properties and the viscosity-probing function has been investigated in comparison with the reported flapping anthraceneimide.
ANATOMI SEKURITISASI PANDEMI COVID-19: KOMPARASI ANTARA PAKISTAN DAN INDONESIA
Authors: Basundoro Alfin Febrian , Karunia Lazarus Andja
Published: May 2021

COVID-19 yang melanda dunia hampir setahun terakhir mengakibatkan krisis yang masif di berbagai negara. Hingga Oktober 2020, WHO mencatat lebih dari 37 juta orang terkonfirmasi positif COVID-19 dengan lebih dari 11 juta kasus aktif.[1] Tidak hanya sektor kesehatan masyarakat, pandemi ini juga menghancurkan sektor strategis lainnya, seperti ekonomi dan sosial-politik. Negara-negara di dunia dipaksa untuk melakukan serangkaian pembentukan kebijakan yang dapat seefektif mungkin mengurangi dampak pandemi terhadap warga negaranya, sekaligus mengatasi aneka permasalahan yang mengikuti pandemi tersebut dalam aneka sektor.[2] Makalah ini berusaha menganalisis secara komparatif dua negara berkembang yang mengalami dampak pandemi COVID-19 yang cukup signifikan, yakni Pakistan dan Indonesia. Sejumlah kemiripan kedua negara, seperti masifnya jumlah penduduk, kolaborasi sipil-militer yang cukup signifikan, penerapan kunci sementara (lockdown) parsial, dan penerapan sejumlah kebijakan lain yang bertujuan untuk menyelamatkan ekonomi nasional menjadi pertimbangan pemilihan topik ini. Sekuritisasi yang dilakukan oleh kedua negara sebagai upaya untuk memposisikan pandemi COVID-19 sebagai isu keamanan nontradisional yang pelik juga menjadi sorotan global terkait bagaimana negara berkembang mengatasi pandemi, dan karenanya, menarik untuk dianalisis. Copenhagen School akan menjadi konsep dasar dalam menganalisis sekuritisasi kedua negara secara komparatif, menekankan pada tahapan-tahapan sekuritisasi.[3] Nantinya, penelitian ini akan membandingkan seberapa efektif tindakan sekuritisasi yang dilakukan oleh kedua negara dalam mengimplementasikan kebijakan penanganan pandemi COVID-19. Tidak hanya itu, penelitian ini juga mencakup apa saja faktor yang menentukan keberhasilan atau kegagalan sekuritisasi kedua negara. Orientasi penelitian akan cukup banyak berkutat pada hubungan sipil-militer kedua negara dan relasinya dalam desekuritisasi, juga sedikit menyentuh isu demokratisasi penanganan COVID-19.[1] World Health Organization, “WHO Coronavirus Disease (COVID-19) Dashboard,” 7 Oktober 2020, https://covid19.who.int.[2] Alex Woodward, “5.4m Americans Lost Health Insurance during Coronavirus Pandemic,” The Independent, 14 Juli 2020, diakses pada 7 Oktober 2020,https://www.independent.co.uk/news/world/americas/coronavirus-health-insurance-pandemic-families-usa-report-a9617226.html.[3] Holger Stritzel, “Securitization Theory and the Copenhagen School,” dalam Security in Translation: Securitization Theory and the Localization of Threat, ed. oleh Holger Stritzel, New Security Challenges Series (London: Palgrave Macmillan UK, 2014), 11–37, https://doi.org/10.1057/9781137307576_2.
Effect of mHealth on Blood Glucose Control in Pregnancies Complicated by Diabetes: A Systematic Review
Authors: Ricci Taylor , Akbar Husain
Published: May 2021

Introduction: For women with diabetes, optimizing blood glucose is critical during pregnancy to reduce the risk of complications. Mobile health interventions contribute to improved blood glucose control among non-pregnant adults with diabetes, but their effect during pregnancy is not known.
Methods: We conducted a systematic review to determine the effect of mobile health interventions on blood glucose control among women with type 1 diabetes, type 2 diabetes, and gestational diabetes mellitus during pregnancy. We searched the databases Ovid Medline, Ovid Embase, The Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov from inception to August 2020. We did not apply limitations to our search. We also examined grey literature and reviewed the reference lists of relevant articles. Studies were eligible for inclusion if they used a randomized controlled trial to determine the effect of mobile health on blood glucose control among women with type 1 diabetes, type 2 diabetes, or gestational diabetes mellitus during pregnancy. A modified version of the Cochrane Randomized Control Trial data collection form and the Template for Intervention Description and Replication checklist guided data collection. We used the Cochrane Risk of Bias 2.0 tool and the Grading of Recommendations Assessment, Development, and Evaluation approach to assess the risk of bias and certainty of the evidence, respectively. Cochrane guidelines for Synthesis Without Meta-analysis informed data analysis.
Results: We included four randomized controlled trials on the effect of mobile health as compared to usual care on blood glucose control among women with gestational diabetes mellitus.
Discussion: Only one of the four trials reported a positive effect direction, while the remaining studies reported negative or conflicting/unclear effects. The certainty of the evidence was low.
Conclusion: Mobile health may have little to no effect on blood glucose control among women with gestational diabetes mellitus. Our synthesis revealed non-significant results and the certainty of evidence was low. However, as there is a current scarcity of randomized controlled trials, future studies are warranted to explore this topic, particularly given the emphasis on virtual healthcare as a result of the COVID-19 pandemic.
Research on the Optimization of Teaching and Learning Path in the Context of Educational Data
Authors: Wang Wenya , Zhang Chunsu
Published: May 2021

With the repeated in-depth development of the technological revolution, the combination of education and technology constantly shows a new form. Modern education and Internet education have become the new direction of the current education development efforts. The development of technology has brought great Gospel for the national education. Based on this, from the traditional and modern perspectives, this paper discusses the form and significance of teaching and learning paths, to show the new value of education brought by the change of teaching and learning paths under the background of educational data.
OPTIMALISASI KADER DALAM PENCEGAHAN COVID 19 DI DESA PASIR LOR KECAMATAN KARANGLEWAS BANYUMAS
Authors: Sumarni Sumarni , Indrayani Eni
Published: May 2021

Corona virus Disease 2019 (COVID-19) is a new type of disease that has never been identified before in humans. COVID 19 can be transmitted from human to human through coughing / sneezing (droplet). To prevent the spread of infection is through regular hand washing with soap and clean water, applying the ethics of coughing and sneezing, avoiding direct contact with livestock and wild animals and avoiding close contact with anyone who shows symptoms of respiratory illnesses such as coughing and sneezing. The objective of this activity is to increase the knowledge and skills of cadres about prevention of Covid 19 through Covid 19 prevention training. The method to be used to realize this program is through preparation, implementation, evaluation and follow-up plans. The results showed cadres who had good knowledge increased from 16% to 40%, while cadres mothers who had sufficient knowledge increased from the previous 24% to 32%. Cadres who have less knowledge have decreased from 60% to 28%. Conclusion; the optimization of health cadres in the prevention of Covid 19 in Pasir Lor Village took place effectively and efficiently. Keywords: Optimization of cadres; Covid-19 prevention
SIMULASI PENANGANAN KORBAN BENCANA BANJIR WILAYAH SEMPOR DI LAPANGAN TEMBAK BEJIRUYUNG SEMPOR KEBUMEN
Authors: Yuda Hendri Tamara , Widyaswara Suwaryo Putra Agina
Published: May 2021

Provinsi Jawa Tengah masuk dalam 5 besar provinsi dengan frekuensi kejadian krisis kesehatan tertinggi dan jumlah korban tertinggi, salah satunya akibat bencana alam. Bencana dapat terjadi kapan saja dan dimana saja termasuk di Kabupaten Kebumen yang merupakan daerah rawan bencana. Bencana yang mengancam di Kebumen yaitu Banjir, tanah longsor, gempa bumi, tsunami, waduk jebol (Sempor dan Wadas Lintang). Untuk meningkatkan pengalaman dan keterampilan mahasiswa KSR, Palasigo , Dosen dan RS Klaster Kesehatan di Kebumen tentang penanganan bencana waduk sempor, telah diadakan pengabdian masyarakat yang meliputi simulasi penanganan korban bencana banjir waduk Sempor di Lapangan Tembak Secata Gombong. Tujuan kegiatan ini adalah meningkatkan pengetahuan dan keterampilan anggota KSR, Palasigo, dosen dan anggota Klaster kesehatan dalam penanganan korban bencana banjir waduk sempor. Metode yang dilakukan yaitu koordinasi awal, simulasi penanganan pasien di RS Lapangan dan kegiatan paska bencana. Kegiatan simulasi penanganan bencana banjir memberikan pengalaman dan praktik mahasiswa KSR, Dosen, dan klaster kesehatan dalam menghadapi bencana. Rencana tindak lanjut yaitu perlunya diadakan kegiatan kepada masyarakat sekitar seperti pelatihan penanganan pertama korban.
PELATIHAN DETEKSI STUNTING PADA KADER POSYANDU DI DESA PEKUNCEN SEMPOR KABUPATEN KEBUMEN
Authors: Utami Wuri , Iswati Ning , Santoso Dadi , Wahyuningrum Asrifah , Gunawan Indra
Published: May 2021

Stunting merupakan masalah kurang gizi kronis yang disebabkan oleh kurangnya asupan gizi dalam waktu yang cukup lama, sehingga mengakibatkan gangguan pertumbuhan pada anak yakni tinggi badan anak lebih rendah atau pendek (kerdil) dari standar usianya (Kemkes.go.id). Pada SK Menkes No. 1995/MENKES/SK/XII/2010). Akibatnya adalah gangguan pertumbuhan (gagal tumbuh) mencakup pertumbuhan fisik dan otak anak. Sehingga selain anak menjadi lebih pendek dibandingkan anak normal se-usianya, anak juga memiliki keterlambatan dalam berpikir.Tujuan pengabdian masyarakat ini adalah memberikan pelatihan  deteksi stunting untuk mencegah terjadinya stunting di Desa Pekuncen. Metode pelaksanaan pengabdian masyarakat ini ceramah dan simulasi dengan melibatkan kader posyandu kesehatan Desa Pekuncen berjumlah 20 peserta. Hasil dari kegiatan ini terdapat peningkatan pengetahuan dibuktikan dengan nilai rata-rata pre test 63dan rata-rata nilai post test 75(meningkat 12) disertai antusiasme yang tingi dari kader posyandu dengan banyak diskusi yang terjadi selama ceramah berlangsung. Kesimpulan dari kegiatan pengmas ini ada peningkatan pengetahuan deteksi stunting sehingga diharapkan kader posyandu Desa Pekuncen mampu melakukan penerapan deteksi stunting dengan benar. Kata Kunci:deteksi stunting;kader posyandu:pelatihan
EDUKASI PENCEGAHAN PENULARAN COVID-19 BAGI TENAGA KESEHATAN DAN PASIEN DI POLIKLINIK RAWAT JALAN OBSGIN
Authors: Brahmana Ivanna Beru
Published: May 2021

Pregnant women need antenatal care (ANC) examinations aimed at fetal health and maternity readiness. Pandemic conditian make ANC implementation could not match the control schedule. This is done so that health workers avoid Covid-19 infection and serving ANC patients who may not be postponed or rejected. Providing education on the prevention of the spread of Covid-19 for health workers and patients at the Obsgyn outpatient polyclinic. Filling out a questionnaire about the patient's knowledge of Covid-19; limited lectures with social distancing conducted to 5-6 collected patients; and providing education on how to wash hands and use masks correctly. The total participants who were given education was 100 people. All participants 100% (100/100) understand about the Covid-19 virus, stay at home, maintain a minimum distance of 1 meter (social distancing), use mask, and wash their hands or use a hand sanitizer. It was different when the respondents came to clinic and assessed by the Nurse what they did was found: 100% (100/100) understood about the Covid-19 disease, 94% (94/100) stayed at home, 100% (100/100) kept their distance at least 1 meter (social distancing), 75% (75/100) wear a mask properly, and 60% (60/100) wash their hands or bring a hand-sanitizer.
PENGUATAN PERAN KADER BINA KELUARGA BALITA MENUJU KAMPUNG KB (COE) DI PUCANGSAWITSURAKARTA STRENGTHENING THE ROLE OF CHILDHOOD FAMILY DEVELOPMENT CHADDREN TOWARDS KAMPUNG KB (COE) IN PUCANGSAWIT SURAKARTA
Authors: Widayati Rina Sri , Sari Dewi Kartika
Published: May 2021

The problem of the lack of public knowledge about the basic needs of new born babies is something that must be considered. With optimal fulfillment, it can improve the health of the baby which becomes a golden start for the next stage. The Kampung KB container in Pucangsawit is the right tool for optimizing activities involving the community through the BKB, BKR, BKL, UPPKS, Priyoutomo, Environmental PKB, Integrated Posyandu, Elderly Post, Family Planning Services, with community empowerment activation activities so that they are able to strengthen BKB cadres become Center of Excellent. Efforts to establish a training center for Omah kriya si Pucang became an innovation in the priority of this activity. Methods ranging from FGD, outreach, training and mentoring so that BKB cadres obtain comprehensive material. An educational approach to all communities, religious leaders, community tokogs, and stakeholders is the main concern in this activity. Activities carried out in May and continued with community assistance so that they are able to monitor and evaluate activities. The results of activities in the correct breastfeeding technique training resulted in an increase in knowledge by 35% from before the training, while the KMC method was able to increase the ability to simulate the method by 45% from before the simulation. Training and mentoring for basic needs training for newborns can increase the knowledge and ability of cadres to practice these activities.
UPAYA PERAWATAN KEHAMILAN DENGAN SENAM HAMIL PADA IBU HAMIL TRIMESTER III DI PUSKESMAS AMBAN MANOKWARI
Authors: Nuryanti Yayuk
Published: May 2021

Pregnancy is a natural and physiological process that every woman experiences. Pregnant women are a high risk group for health problems. Stress is a health problem that often occurs in pregnant women. The goals of pregnancy exercise include reducing stress and preparing physically and psychologically for pregnant women. The purpose of the activity is to increase knowledge and empower pregnant women to care for their health independently. The method used is pregnancy exercise lectures and exercises. Participants in pregnancy exercise were 20 trimester III pregnant women. Implementing activities consisted of lecturers, health center midwives and students. The results of the activity were obtained through interviews which explained that participants learned about the benefits of pregnancy exercise, pregnancy exercise can make the body comfortable, and participants are interested in pregnancy exercise. The results of this activity can be concluded that the class of pregnant women must be held at the Puskesmas with activities such as pregnancy exercise.
PROGRAM KEMITRAAN KELOMPOK PENGURUS DESA "POLAMANKU" TENTANG PENCEGAHAN PENULARAN VIRUS CORONA
Authors: Ristanto Riki
Published: May 2021

Dukuh Polaman Desa Bedali Kecamatan Lawang Kabupaten Malang is a tourist village known as "Polamanku". The variety of existing tourist infrastructure has the potential to become a gathering place for visitors, especially during holidays, but these facilities and infrastructure have not been facilitated by hygiene facilities, especially for the prevention of the corona virus contagious disease (covid-19). The purpose of this community service activity is to increase the knowledge and skills of partners regarding the management of prevention and control of the corona virus (covid-19). This community service is carried out through the method of seminars, mentoring, and procurement of tools for partners. This community service was attended by 15 administrators of the "Polamanku" tourism village. The target output of community service that has been achieved is in the form of services and products. Services in this case are in the form of providing seminars on management of prevention of transmission of the corona virus (covid-19) as well as assistance on the use of thermogun, 6 steps to wash hands, and use of masks. Through this method it is proven to be able to increase partners' understanding of the corona virus (covid-19) and the prevention of transmission (100%). The products that have been produced are in the form of banners and hand washing tools as a means of supporting the sustainability of the corona virus (covid-19) transmission prevention program. It is hoped that this activity can be sustainable independently carried out by partners and can inspire other similar tourism vehicles, considering that these activities have not been carried out a lot.
UPAYA PENGUATAN PROGRAM STIMULASI, DETEKSI DAN INTERVENSI DINI TUMBUH KEMBANG (SDIDTK) MELALUI PEMERIKSAAN ANTROPOMETRI PADA ANAK PRASEKOLAH
Authors: Rahayu Suci Fitri , Anggeriyane Esme , Mariani Mariani
Published: May 2021

The importance of paying attention to nutritional status in early childhood is useful for maximizing the growth phase of early childhood. One way to assess nutritional status for early childhood can be assessed by means of anthropometric measurements. Anthropometric measurements are measurements of various dimensions and body compositions of various ages, such as baby length, head circumference, height, weight, chest circumference, and upper arm circumference. TK Aisyiyah 15 Bustanul Athfal Banjarmasin is one of the schools that has not implemented early detection of the growth and development of pre-school children because the teachers do not understand how to examine and document the results of the examination. Efforts to strengthen the Stimulation, Detection and Early Development Development Program (SDIDTK). Methods ranging from FGDs, training and mentoring so that teachers acquire comprehensive skills in anthropometric examinations. The activity was carried out in August and was continued with mentoring for teachers to be able to monitor and evaluate activities. The results of activities in efforts to strengthen stimulation, detection and early intervention programs for growth and development produce skills for teachers in conducting anthropometric examinations and screening children's growth and development. Efforts to strengthen the program of stimulation, detection and early intervention for growth and development can increase teachers' knowledge in conducting anthropometric examinations and growth screening.
THE INVOLVEMENT OF PARENTS FOR THE ROLE OF THE DRUG ABUSE PREVENTION AMONG TEENAGERS IN MUHAMMADIYAH HIGH SCHOOL OF GOMBONG KEBUMEN
Authors: Marsito M
Published: May 2021

According to the Foundation of Yayasan Cinta Anak Bangsa (YCAB in Jakarta, 7% of teens aged 12 to 19 years had been claimed for drug abuse trial. a preliminary study to the numbers of education personnels and high school students of Muhammadiyah High School of Gombong,  11.5% o 40 staff personnel employees had ever tried drug abuse. The study was aimed to identify the correlation between the role of parent to the prevention of drug abuse of the high school of Muhammadiyah Gombong. This study used descriptive correlation design with cross sectional approach to variables consisting of the independent variable of student's home and the role of parents. The dependent variable is the drug abuse prevention. Total sample consisted of 186 adolescents aged 13 to 21 years taken by using accidental sampling technique. The analysis used univariate and bivariate analysis with chi square test.The results found that there was no correlation between the parents' involvement with drug abuse prevention where p = 0.856, there was a correlation between role's and the drug abuse prevention with p = 0.000.Thus the role of parents needs to be enhanced by giving education about the danger of drug abuse. It is necessary to remind the role of parents in family to educate the children about the danger of drug abuse and to give good examples and become true role models for their children at home and daily life Keywords: the role of parents, and the prevention of drug abuse, teenagers.
PENATALAKSANAAN PERSIAPAN PASIEN PREOPERATIF DI RUMAH SAKIT UMUM DAERAH KABUPATEN CIAMIS
Authors: Apipudin Aap , Marliany Heni , Nandang Arif
Published: May 2021

Procedure preoperative actions in some hospitals have developed such reference to the needs of patients who will do the surgery. This procedure is expected to become a paramedic guidelines in an effort to prepare the patient preoperatively, so the preoperative preparation can be done well. The purpose of this study is find a picture of the management of the patient's preoperative preparation in hospital.This research use descriptive research. The population in this study were surgical patients in the General Hospital of Ciamis. The sampling technique by means of quota sampling a total sample of 30 people.It is known that the management of physical preparation in the patient's preoperative 83.3% implemented, supporting the management of the patient's preoperative preparation 100% implemented, preparation Management informed consent on the patient's preoperative 100% implemented and management of mental preparation / psychic on the patient's preoperative 100% implemented. The overall results showed that the majority of the category held as many as 25 people (83.3%) Keywords: Management, Preoperative
ANALISA SITUASI TUBERKULOSIS (TB) DI KABUPATEN KEBUMEN
Authors: Yuniar Isma , Sari Kanthi Pamungkas , Yudha Hendry Tamara
Published: May 2021

Tuberkulosis (TB) merupakan penyebab kematian utama di banyak negara-negara berkembang. Diperkirakan sekitar 2,7 juta jiwa meninggal karena TB setiap tahunnya di seluruh dunia. Salah satu isu strategis yang dihadapi oleh Dinas Kesehatan maupun masyarakat Kabupaten Kebumen adalah angka kesakitan dan kematian penyakit menular dan tidak menular masih tinggi. Penyakit-penyakit menular/infeksi sampai saat ini belum semua dapat diatasi, disisi lain angka kesakitan dan kematian beberapa penyakit tidak menular dan degeratif cenderung meningkat. Hal tersebut juga diperparah dengan kondisi rendahnya kualitas dan cakupan kesehatan lingkungan masyarakat. Cakupan sanitasi dasar seperti cakupan jamban keluarga, cakupan sarana pembuangan air limbah rendah, serta proporsi rumah sehat masih rendah.Analisa Situasi TB di Kabupaten Kebumen bertujuan untuk melakukan kajian terhadap kondisi penanggulangan penyakit TB secara komprehensif dengan menghubungkan berbagai aspek yang terkait lainnya. Berdasarkan hasil analisa situasi tersebut dapat dijadikan rekomendasi agar upaya mengatasi permasalahan TB secara optimal. Jumlah kasus dan angka penemuan kasus  TB  Paru BTA + masih di bawah standar. Penyebab langsungnya: sumber daya tenaga kesehatan yang terbatas dan kesadaran pasien untuk periksa rendah. Succes rate masih di bawah standar  Penyebab langsungnya: terlambat mengambil keputusan untuk berobat dan terlambat mendapatkan pelayanan kesehatan. Angka kematian akibat TB menunjukan tren meningkat Penyebab langsungnya: kekebalan tubuh menurun dan pengobatanya terhenti.Rekomendasi terdiri dari tiga hal yaitu Penanggulangan TB di daerah merupakan tanggungjawab bersaama, mengembangkan jaringan kemitraan berdasarkan skema prioritas.Program disusun secara implementatif dan realistis dilakukan secara berencana, terus menerus dan berkesinambungan
POLA MAKAN DAN POLA AKTIFITAS PADA ANAK OBESITAS DI SD ISLAM AL-HIKMAH SELOKERTO KECAMATAN SEMPOR
Authors: Iswati Ning , Desyarti Neza , Nurlaila Nurlaila
Published: May 2021

Obesity has become a worldwide health problem. Obesity is the impact of energy imbalances over a period of time. Many factors cause excessive obesity, but these can be simplified into eat more and move less. The research to know dietary habit and activity pattern towards obesity of elementary school children in Al-Hikmah Islamic Elementary School at Selokerto, Sempor, Kebumen. Thisresearch is an analytic research with total sampling technique as many as 34 respondents. Data collection was done by filling out the questionnaires with univariat analysis. Based on the research conducted, finding out 61,8% of children have good dietary habit and 41,2% of them have less activity. The Conclusion that children with obesity have good dietary habit and children have less activity. Since there is it is possibly related by other factors, such as genetic, socioeconomic, environment, hormonal, psikologis and gender.There should be next reseach on the other factors, such as genetics, socioeconomic, environmental, hormonal, psychological and gender.
HUBUNGAN KARAKTERISTIK INDIVIDU DENGAN KESIAPSIAGAAN PERAWAT PUSKESMAS DALAM MENGHADAPI BENCANA BANJIR DI KABUPATEN BANDUNG
Authors: Fatih Hudzaifah Al
Published: May 2021

AbstrakKesiapsiagaan bencana merupakan rangkaian kegiatan yang dilakukan untuk mengantisipasi bencana sekaligus mengurangi angka morbiditas dan mortalitas. Tujuan dari penelitian ini adalah untuk mengidentifikasi karakteristik individu (usia, lama kerja, pengalaman bencana sebelumnya dan pengalaman di tempat pengungsian) perawat Puskesmas dan tingkat kesiapsiagaan bencana mereka, serta untuk menguji hubungan diantara variabel-variabel tersebut. Penelitian ini menggunakan desain potong lintang dengan dengan 46 responden dipilih menggunakan metode convenient sampling dari delapan puskesmas rawan banjir di Kabupaten Bandung. Data di analisis menggunakan statistik deskriptif dan Spearman Correlation untuk menentukan hubungan antar variabel.  Hasil penelitian menunjukkan bahwa mayoritas perawat Puskesmas memiliki kesiapsiagaan sedang (78,3%) dan sebagian kecil memiliki kesiapsiagaan tinggi (21,7%). Hubungan yang signifikan ditemukan antara usia dan kesiapsiagaan bencana (rs= 0.309, p = 0,037) dan lama kerja dengan kesiagaan bencana (rs= 0.325, p = 0,027). Untuk memperbaiki tingkat kesiapsiagaan bencana Perawat Puskesmas dalam rangka mengurangi angka morbiditas dan mortalitas dilakukan dengan memberikan pelatihan dan edukasi tentang kesiapsiagaan bencana bagi perawat muda yang belum berpengalaman dalam menghadapi bencana banjir.Kata Kunci : Banjir, Karakteristik Individu, Kesiapsiagaan Bencana, Perawat Puskesmas
Dampak Psikologis Gempa Bumi terhadap Kelompok Rentan : Lansia
Authors: Mutianingsih Mutianingsih , Mustikasari Mustikasari
Published: May 2021

Abstrak  Gempa bumi merupakan salah satu bencana yang paling mengancam kehidupan. Terjadinya gempa bumi dapat berdampak pada berbagai aspek kehidupan, dimana salah satunya adalah aspek psikologis. Lansia merupakan salah satu kelompok rentan dalam managemen bencana, sehingga dampak psikologis akan lebih rentan dialami lansia dibandingkan dengan usia yang lebih muda. Berdasarkan telaah literatur didapatkan bahwa dampak psikologis yang terjadi pada survivor lansia pasca gempa bumi yaitu kecemasan, depresi dan post traumatic stress disorder (PTSD). Beberapa faktor yang berkontribusi terhadap terjadinya berbagai dampak psikologis pada survivor lansia diantaranya usia, jenis kelamin, keterbatasan fisik, penurunan fungsi kognitif  dan keterpaparan terhadap gempa bumi serta terjadinya cedera atau kehilangan orang yang dicintai. Diperlukan suatu upaya kesiapsiagaan guna meminimalisir terjadinya dampak psikologis pada korban lansia. Kata Kunci: dampak psikologis, gempa bumi, lansia AbstractAn earthquake is one of the most life-threatening disaster. The occurrence of earthquake can affect various aspects of life, wich one of them is a psychological aspect. Elderly is one of the vulnerable groups in disaster management, so that the psychological impact will be more susceptible in elderly compared to younger age. Based on the literature review, it was found that the psychological impact of post-earthquake in elderly survivors was anxiety, depression and Post Traumatic Stress Disorder (PTSD). Factors that contribute to the occurrence of various psychological impacts on elderly survivors include age, gender, physical limitations, decreased of cognitive function and exposure to earthquakes with injury or loss of loved ones. A preparedness effort is needed to minimize the psychological impacts on elderly survivor. Keyword : psychological impact, earthquake, elderly
The Importance of Heart Rehabilitation for Coronary Heart Disease Patients
Authors: Husein Muhammad
Published: May 2021

Coronary heart disease has now become a global cardiovascular problem with a high mortality rate. Regarding the mortality and morbidity rates of patients with high myocardial infarction, appropriate treatment is needed for patients. Three interventions were performed on coronary heart disease patients, thrombolytic interventions, percutaneous coronary intervention, and coronary artery graft bypass (CABG). Cardiac Rehabilitation is a treatment protocol recommended for the treatment of heart disease, and has been developed from a simple multidisciplinary sponsored patient monitoring process that requires patient education, specially designed exercise programs, modification of patient risk factors, and patient benefits. Identifying incentive programs will increase the level of participation in rehabilitation programs, to help patients achieve the main benefits of cardiac rehabilitation
RESPON PSIKOLOGIS DALAM SIKLUS PENERIMAAN MENJALANI TERAPI HEMODIALISA PASIEN GAGAL GINJAL KRONIK
Authors: Mardiati Agustin M.Kep.Sp.Kep.J Ike
Published: May 2021

Gagal ginjal kronik adalah kondisi dimana ginjal sudah tidak mampu lagi mempertahankan keseimbangan cairan dan sisa metabolisme, untuk membantu dalam fungsi ginjal yang rusak dilakukan terapi hemodialisa. Prosedur hemodialisa ini sangat bermanfaat untuk pasien, namun juga menyebabkan dampak psikologis. Dampak psikologis yang muncul salah satunya dikarenakan proses hemodialisa yang membutuhkan waktu jangka panjang untuk dijalani seorang pasien,  hal ini membutuhkan waktu untuk menerima dalam menjalani terapi hemodialisa tersebut.Tujuan Penelitian: Untuk mengetahui respon psikologis dalam tahap-tahap penerimaan menjalani terapi hemodialisa pada pasien gagal ginjal Kronik di PKU Muhammadiyah Gombong. Metode Penelitian: Penelitian ini menggunakan metode penelitian deskriptif kualitatif dengan menggunakan pendekatan interpretive dan jenis penelitian fenomenologi deskriptif Pada 8 partisipan yang sudah mencapai saturasi data.Hasil Penelitian: Hasil penelitian menunjukan pasien yang menjalani terapi hemodialisa mengalami respon psikologis karena adanya kecemasan, kematian dan tidak kunjung sembuh. Dengan siklus penerimaan dimulai dari respon penolakan, marah, tawar menawar, depresi, dan sampai respon penerimaan. Dalam siklus ini partisipan membutuhkan waktu untuk menerima dalam menjalani hemodialisa. Rekomendasi: Memberikan gambaran tentang fenomena respon psikologis dalam siklus penerimaan menjalani terapi hemodialisa pada pasien gagal ginjal.Keywords:Respon Psikologis; Hemodialisa; Gagal Ginjal Kronik
APLIKASI MHEALTH DALAM DETEKSI, MONITORING DAN PERUBAHAN GAYA HIDUP PASIEN PENYAKIT JANTUNG
Authors: Puspita Vema Tiyas , Hariyati RR. Tutik Sri
Published: May 2021

Pendahuluan : Penyakit jantung memiliki prevalensi kematian dan morbiditas yang tinggi. Penyebab dari penyakit kardiovaskular ini karena merokok, meningkatnya tekanan darah, penyakit diabetes mellitus, kolesterol, obesitas, diet yang tidak sehat dan aktifitas fisik yang kurang. Ketidakpatuhan minum obat juga merupakan faktor pencetus kekambuhan. Salah satu teknologi yang dapat digunakan untuk mencegah dan monitoring pasien penyakit jantung dengan menggunakan  aplikasi mhealth. Tujuan dari studi literature ini adalah untuk mengetahui aplikasi mhealth yang dapat digunakan untuk pasien jantungMetode :Tinjaun pustaka telah dilakukan untuk mencari jurnal terkait yang dipublikasikan pada tahun 2013 sampai dengan 2018 dengan melalui pencarian database di EBSCO, CINAHL, Wiley, Scopus, Proquest, Sage Publications, Science Direct dengan kata kunci “mhealth cardiac”, “mhealth cardiac nursing”, mhealth nursing”, “mhealth smartphone application”.Hasil : berdasarkan penelusuran jurnal didapatkan lima jenis aplikasi mhealth baik yang berbasis android maupun iOS,  yaitu: AliveCor™ECG,  Wellframe Application,  Care4Heart,  HeartKeeper app, dan  HeartMapp app.Kesimpulan : Berbagai aplikasi mhealth telah dikembangkan, tetapi hanya beberapa yang sudah dilakukan uji fisibilitas dan akseptabilitas. Peran perawat sangat penting dalam memilih aplikasi yang tepat dan sesuai digunakan untuk pasien dengan gangguan jantung.Kata kunci: aplikasi kesehatan, aplikasi mhealth, penyakit jantung
Social Interaction on Patients with Schizophrenia in Psychiatric Hospital
Authors: KURNIASARI CECILIA INDRI
Published: May 2021

Social interaction is one of important indicator in the recovery process of mental patients, especially in patients with schizophrenia. Active social interactions can help patients with schizophrenia to socialize, while less active social interactions can cause social isolation to the risk of suicide. The purpose of this study was to determine the social interaction of patients with schizophrenia in psychiatric hospital. The number of participant in this study were 52 patients. Sampling with a purposive sampling technique. Data were collected using Social Interaction Questionnaire and Behavior Observation Sheet consisting of 18 statements. The analysis of this study was using univariate analysis with table of frequency distribution. The results showed that social interactions in schizophrenia patients were 45 patients with less active interacting categories, 5 patients with moderately active interacting categories, and 2 patients with active interacting categories. The results of the study can be used as a reference in determining appropriate nursing therapy in increasing social interaction in schizophrenia patients in mental hospitalsKeywords: social interaction; social psychological factors; schizophrenia;
PENGETAHUAN PERAWAT DALAM MENERAPKAN EARLY WARNING SCORE SYSTEM (EWSS) DI RUANG PERAWATAN
Authors: Suwaryo Putra Agina Widyaswara , Sutopo Rahmat , Utoyo Bambang
Published: May 2021

Salah satu strategi untuk menurunkan angka kematian akibat henti jantung adalah dengan menerapkan Early Warning Score System (EWSS). EWSS merupakan sistem skoring fisiologis dalam menganalisis hasil pemeriksaan tanda-tanda vital untuk mendeteksi perubahan atau perburukan kondisi pasien sebelum terjadi kegawatan. Penelitian ini bertujuan untuk mengetahui bagaimana penerapan Early Warning Score System (EWSS) di Ruang Perawatan RSUD dr Soedirman Kebumen. Penelitian ini menggunakan metode non-eksperimen dengan desain analitis deskriptif. Subjek penelitian diambil menggunakan teknik total sampling sebanyak 39 responden. Hasil penelitian didapatkan pengetahuan perawat tentang EWSS baik (35.9%), sebagian besar pendidikan perawat D3 (61.5%), mengikuti pelatihan BT&CLS (87.1%), lama kerja kurang dari 5 tahun (48.7%), dokumentasi EWSS lengkap (35.8%) dan penerapan EWSS dalam kategori cukup (51.3%). Ada hubungan tingkat pengetahuan perawat dengan penerapan Early Warning Score System (EWSS) di ruang perawatan yaitu Dahlia dan Terate RSUD dr Soedirman Kebumen. Sosialisasi yang berkaitan dengan Early Warning Score System (EWSS) perlu dilakukan untuk meningkatkan pengetahuan perawat dan meningkatkan mutu pelayanan keperawatan.
The Effect Of Crossword Puzzle Therapy (CPT) On The Cognitive Function Of Elderly In Sudagaran Old Age Home (PPSLU), Banyumas
Authors: Komsin Nabila Karimah , Isnaini Nur
Published: May 2021

Lanjut usia yang mengalami penurunan fungsi kognitif akan berakibat terhadap aktivitas sehari-hari dan ketergantungan terhadap orang lain. Solusi untuk mengatasi masalah yang terjadi yaitu dengan meningkatkan fungsi kognitif pada lanjut usia. Crossword Puzzle Therapy (CPT) merupakan salah satu terapi non farmakologi untuk menghambat terjadinya penurunan fungsi kognitif. Tujuan penelitian ini untuk mengetahui pengaruh crossword puzzle therapy (CPT) terhadap fungsi kognitif  lansia di panti  pelayanan sosial lanjut usia (PPSLU) sudagaran banyumas. Penelitian ini menggunakan desain penelitian Quasy Experiment dengan pendekatan Pre and Posttest with Control Group. Sampel penelitian sebanyak 36 orang lansia dengan menggunakan teknik total sampling. Instrument penelitian menggunakan MMSE. Analisa data menggunakan Mann Whitney. Hasil penelitian menunjukan karakteristik jenis kelamin responden mayoritas perempuan, rata-rata usia responden pada rentang usia 60-74 tahun, dan pendidikan responden rata-rata tidak sekolah dan tamat SD. Skor MMSE lansia yang mendapatkan crossword puzzle therapy (CPT) mengalami kenaikan secara bermakna daripada lansia yang tidak mendapatkan crossword puzzle therapy (CPT). Hasil uji Mann Whitney diperoleh nilai Asymp.Sig sebesar 0.000 (P value < 0,05) ada pengaruh crossword puzzle therapy (CPT) terhadap fungsi kognitif  lansia di panti  pelayanan sosial lanjut usia (PPSLU) sudagaran banyumas, uji Shapiro-Wilk p value < 0,05.Keywords: crossword puzzle therapy (CPT); lansia; fungsi kognitif.
NORMA SUBYEKTIF DAN NIAT BERPENGARUH TERHADAP PERILAKU MEROKOK REMAJA DI YOGYAKARTA
Authors: Riyadi Sujono
Published: May 2021

ABSTRACTBackground: Smoking behavior is an act that is very detrimental to the health of the perpetrators and those around them. In cigarettes there are chemical substances that are very dangerous for one's health, both active smokers and passive smokers. The purpose of this study was to determine the effect of the non-smoking subjective norm and non-smoking intention on the smoking behavior of adolescents in Kulon Progo Yogyakarta.Subject and Method: This was a case control study conducted in Kulon Progo, Yogyakarta, from April to June 2018. A total of 400 adolescents consisiting of 200 smokers and 200 non smokers were selected for this study. The dependent variable was smoking behavior. The independent variables were intention and subjective norm. The data were collected by questionnaire and analyzed by a path analysis.Results:  The decision not to smoke was associated with strong intention (b= 1.74; 95% CI= 2.29 to 1.18; p<0.001), favorable subjective norm (b= 1.58; 95% CI = 0.99 to 2.18; p<0.001)Conclusion: The decision not to smoke is associated with intention, subjective norm. Keywords: Smoke, Intention, Subjective norm.