bluuebunny/crossref_metadata_2025 huggingface dataset:
Edge Detection and Defects Checking of Binder Clip and Welded Joint using a Python-Based Algorithm: Applications in Quality Inspection
Authors:   Department of Mechanical Engineering, Rajalakshmi Engineering College (Autonomous), Chennai- 602105, India, Senthil Murugan S. , Sathiya P. ,   Department of Production Engineering, National Institute of Technology, Trichy-620015, India, Hariharan K. ,   Department of Mechanical Engineering, Rajalakshmi Engineering College (Autonomous), Chennai- 602105, India, McJone J. ,   Department of Mechanical Engineering, Rajalakshmi Engineering College (Autonomous), Chennai- 602105, India, Nithiyanantham K. K. ,   Department of Aeronautical Engineering, Rajalakshmi Engineering College (Autonomous), Chennai- 602105, India
Published: January 2024

Machine vision is a computer vision system that enables a computer to work on image-based inspection and analysis for different applications. In this computer vision, a camera and sensor were used to view an image for its analysis with the help of some sort of algorithms, then processed to infer the image-based data. Machine vision systems along with Python programs can be used for many interdisciplinary applications like weld inspection, online monitoring in manufacturing auto components etc. In this study, the “Edge detection python algorithm” was developed and run through “Google Colab” notebook to inspect the edges and the boundaries of samples like faying surface-modified friction welded dissimilar joints and a binder clip (paper clamp) to check any defects or cracks and straightness etc. With the help of this Python algorithm, the edge detection was done by Sobel, Scharr, and Prewit operators. An input image of the weld joint and the binder clip were converted into Otsu’s binary threshold image. The matrix vision camera and the CMOS sensor were used in the machine vision set-up to take the images. This written algorithm is helpful to trace the edges of any kind of solids components. The edges of the binder clips and the weld joint/zone were detected. The binder clips were inspected under two different cases namely the clip in folding condition (Case I) and the binder clip in unfolding condition (Case II). The results showed a defect that was identified in the weld zone and no bending was in the binder clips. This kind of study is useful in manufacturing industries for quality inspection purposes with a new machine vision set up for online inspection of fabricated components like nuts and bolts etc.
A Review of Friction Welding Research Addressing the Influence, Development, Similar & Dissimilar Welding
Authors:   Rajalakshmi Engineering College (Autonomous), Chennai - 602105, Tamilnadu, India, Senthil Murugan S. , Sathiya P. ,   National Institute of Technology, Tiruchirappalli – 620015, Tamilnadu, India
Published: January 2024

This review paper discusses the recent research work carried out in the frictional joining of dissimilar and similar alloys through the friction welding (FW) process with various parameters and modifications. It includes further the latest developments and advances in the research on FW and the influences of FW’s process parameters on the quality of joints and their properties. The specimens’ faying surfaces can also influence the joint properties as the surface modifications stimulate or change the metal joints’ bonding according to the welding parameters selected during FW. Though the rise of friction pressure (FP) during FW improves the strength of the joints, the improper selection of parameters leads to metal damage. It feels better if the axial shortening is less than 30 mm for FW of soft metals. The axial shortening values are less than 25 mm for the hemispherical bowl-type faying surfaces under 18 bar FP and it is noted that the bevel-type tapered faying surfaces increase the shortening. FW provided very narrow weld interfaces with around 5-10 µm width. With a low FP, it was possible to obtain a maximum of 100 % efficiency by modifying their faying surfaces. The small-diameter soft material needs less FP and friction time. The microstructure modification is possible and the weld joint is shown as U and V shapes for the bowl and tapered faying surfaces. It further increases the contact area and thus increases strength.
S-FMECA: A Novel Tool for Sustainable Product Design - Additive Manufacturing
Authors:   Laboratory of Mechanical Engineering (LGM), National Engineering School of Monastir (ENIM), University of Monastir, Rue Ibn El Jazzar, 5000 Monastir, Tunisia Higher Institute of Technological Studies of Sousse, Cité Erriadh, 4000 Sousse, Tunisia, Chtioui N. , Gaha R. ,   Roberval Mechanics Laboratory UMR-CNRS 7337, Royallieu Research Center, University of Technology of Compiègne, France, Chatti S. ,   Laboratory of Mechanical Engineering (LGM), National Engineering School of Monastir (ENIM), University of Monastir, Rue Ibn El Jazzar, 5000 Monastir, Tunisia, Benamara A. ,   Laboratory of Mechanical Engineering (LGM), National Engineering School of Monastir (ENIM), University of Monastir, Rue Ibn El Jazzar, 5000 Monastir, Tunisia
Published: January 2024

The choices made in the early design stage (EDS) will largely define the environmental impacts of a product. The purpose of this paper is to develop an eco-design method used for assessing semi-quantitatively the sustainability of an additively manufactured product since the EDS. This article presents a semi-quantitative method to support EDS-conscious environmental decisions. A novel Sustainable-Failure Mode, Effect, and Criticality Analysis (S-FMECA) tool is developed to support designers in the conceptual design phase, to guide the choices, and to provide a valuable evaluation of the future additively manufactured product. Through the integration of the environmental aspects in FMECA analysis, systematic prevention of errors, and enhancement of sustainability since the EDS would be the main advantage of this tool.
Optimization of the treatment of caries permanent teeth with different degree of enamel resistance beside children with innate unjoining lip and palate
Authors: Ashurov G. G. , Obidov S. A. , Karimov S. M.
Published: January 2024

Aim. To select the optimal method for caries treatment of permanent teeth with different degree of enamel cariesresistance in children with innate unjoining lip and palate.

   Materials and methods. Beside 40 children was examined the condition of hard tissue of teeth. In dependent of enamel resistance was using atraumatic restorative treatment with using of new technology of prepared teeth by minimum invasive method with following filling by glassionomer cement. Among examined children, using enamel resistance test, revealed four level of resistance. Depending on the enamel resistance level, corresponding treatment was provided: a child with high and moderate enamel resistance was organized traditional treatment of caries. Children with low and very low enamel resistance had a complex of treatment-preventive approach in 3 directions: atraumatic restorative treatment of caries by method of minimal invasive prepared; local pathogenetic remotherapy by deep fluoridation combined with professional oral hygiene lessons, followed by filling of glassionomer’s cement; general pathogenetic therapy (in conjunction with the internist oral administration of calcium preparations, vitamin complexes and rational nutrition).

   Results. Complex of integration approach treatment of caries in children with innate unjoining lip and palate was highly reliable (р<0.001) effective in depending of source level enamel resistance. This approach helped prevent the development of secondary caries around early assessed filling material.

   Conclusions. Beside children with innate unjoining lip and palate in the course of active realization of the complex method of the treatment tooth decay was noted reliable reduction of cariesology complications after filling of carious cavity under low and very low enamel resistance on all under study parameters.
Regeneration of the apical region of the tooth after the treatment of destructive periodontitis with cement resorption
Authors: Glinkin V. V. , Voronov I. A.
Published: January 2024

Aim. Destructive changes in the tissues of the tooth and periodontium entail resorption of the hard tissues of the tooth in the apical region. The goal is to identify morphological changes in root tissues with destructive periodontitis and resorption phenomena after the treatment of the tooth with calcium-containing preparations using a scanning electron microscope.

   Materials and methods. Examination of teeth treated for destructive forms of periodontitis with apical resorption was performed using a JSM-6490LV scanning electron microscope (JEOL, Japan) with an energy-dispersive attachment INCA Penta FETx3 (OXFORD Instruments, England).

   Results. In the apical part of the root there is a cellular mixed layered cementum. The dentin and the dentin-cementum junction are highly calcified. On top of them is cellular cement with lacunae of cementoblasts. The relief of the zone of cell-free cement has a wavy structure, consists of dense collagen fibers with a high content of calcium. With external root resorption, we observe extensive destruction of the cementoblast layer. An area of newly formed cementum was found inside the apical foramen. On the apical surface, where the resorption covered the dentin layer, there was an area of newly formed cementum. Its cellular layer consisted of round-shaped cells rising above the tissue of a homogeneous structure, smoothly flowing into the spongy tissue denting the bone.

   Discussion. It can be assumed that prolonged use of calcium-containing drugs leads to calcification. The presence of dense connective tissue in the periodontium indicates regenerative processes. The control of cement formation remains uncertain.

   Conclusions. Perhaps we are seeing a reparative atypical regeneration of the cement of the apical part of the tooth root. Dentinal calcification. In the lateral parts of the apical region, there is an outer layer of cementum with no cementoblasts. An increase in the thickness of the cement was noted. It can be assumed that we observe the phenomenon of osteogenesis in the area of strong resorption.
Current Aspects of Regenerative Endodontics: A Systematic Review
Authors: Mitronin A. V. , Archakov K. A. , Ostanina D. A. , Mitronin Yu. A. , Khizrieva T. V.
Published: January 2024

Relevance. The modern concept of endodontic treatment in most clinical cases involves extirpation of the pulp with the loss of its plastic, trophic, sensory, and protective functions. In this regard, the search for ways to recreate lost cells and the main substance of the pulp and periodontium to replace the intraradicular space with “vital” tissue. Regenerative endodontics based on the principles of tissue engineering and offers techniques for restoring damaged tissues of the pulp-dentin complex based on the use of stem cells, growth factors, and an organic matrix.

   Aim. Systematize information presented in scientific articles about research conducted, opportunities and development prospects in the field of regenerative endodontics.

   Materials and methods. A search of literature sources was carried out in the PubMed, dissercat.com, elibrary database.ru, cyberleninka.ru, by keywords, “regenerative endodontics”, “stem cells”, “growth factors”, “pulp-dentin complex” with a choice of article types “Clinical Trial”, “Meta-Analysis”, “Review”, "Systematic Review".

   Results. After analyzing the literature review, an idea was obtained about the current stage of development of regenerative endodontics, preclinical and clinical studies on the restoration of the pulp-dentin complex. Clinical cases based on the triad of regenerative endodontics are presented, as well as an algorithm for performing these therapeutic procedures.

   Conclusions. Regenerative endodontics is a rapidly developing discipline whose clinical advances are primarily related to the treatment of immature tooth roots, which results in continued root development. Subsequent scientific research is aimed at obtaining significant results in the treatment of a fully formed permanent tooth, which will ensure a unique restoration of the immunological, sensory and protective properties of the pulp-dentine complex.
Features of temporary teeth hard tissues affecting caries resistance
Authors: Bagdasarova I. V. , Kostinskaya M. V. , Miral Al. Kamme
Published: January 2024

Aim. Features of microscopic structure of enamel and dentin of intact temporary teeth, which are the cause of their reduced caries resistance.

   Materials and methods. Current information in the electronic databases Google Scholar and PubMed was examined through a systematic literature review. Articles with content related to the prevalence of dental caries in temporary teeth and the relationship between caries and tooth hard tissue structure were selected and included.

   Results. A total of 327 publications were reviewed. After analyzing the literature according to the inclusion criteria, the final number was 52.

   Conclusions. Based on the analyzed data, the structure of the hard tissues of temporary teeth is a predisposing factor for the occurrence and development of dental caries. Decreased thickness of enamel and dentin, increased concentration of organic matrix in them due to incomplete mineralization, microporosity of enamel, abnormal development of dentin layers, increased number of hypomineralized and irregular areas, underdevelopment of pulp, impaired function of odontoblasts, increased adhesion of microorganisms to the enamel surface – all these features contribute to the rapid and progressive development of caries in temporary teeth.
Last Generation Bis-GMA Free Composite For Indirect Posterior Restorations: A Case Report
Authors: Delgado M.
Published: January 2024

Scientific literature put in evidence the importance to use biocompatible materials, free from any substance that can be toxic for the human body, for this reason a Bis-GMA free composite material is used that shows cytotoxicity equal to zero. Nowadays composite materials can be used with direct and indirect technique. In this case report we decided to provide an indirect composite restoration, this is an excellent option in absence of coronal destruction, as we improve the anatomic contour, and we also increase the physical properties as we also post curing the element in a light curing unit for indirect technique that must not exceed the 80°C /176 °F to avoid to damage the inorganic matrix of the composite.
Efficacy evaluation of using hypoallergenic toothpastes in children with a burdened allergy anamnesis
Authors: Kondratenko I. D. , Nikolskaya I. A. , Kuliev R. M. , Vostrikov V. O. , Voronetskaya V. A. , Novikova A.
Published: January 2024

Aim. To conduct a clinical evaluation of the efficacy of using hypoallergenic children's toothpastes “R.O.C.S. PRO Baby" and "R.O.C.S. PRO Junior Creamy Pudding" in patients aged 2 to 11 years with a burdened allergy history.

   Materials and methods. The study included 58 children aged 2 to 11 years with a burdened allergy history. Before the start of the study, they were divided into two groups: the first included 28 children aged 2-3 years, whose parents had been brushing their teeth with « R.O.C.S. PRO Baby» hypoallergenic paste for 3 months. The second group included 30 childrenaged 6-11 years who provided oral care using the paste « R.O.C.S. PRO Junior Cream pudding ». During the control dental examinations, the determination of the possible locally irritating and allergenic effects of the studied toothpastes was carried out by visual examination of the oral mucosa of patients of both groups, as well as interviews and questionnaires of study participants and their parents. In patients of the second group, the hygienic condition of the oral cavity was assessed by determining the PHP hygiene index, PMA and SBI indices to assess the condition of periodontal tissues.

   Results. During the study, patients with a burdened allergy history did not have a locally irritating and allergenic effect of hypoallergenic toothpastes "R.O.C.S. PRO Baby" and "R.O.C.S. PRO Junior Cream pudding" on the oral mucosa. When using toothpastes, there was a significant decrease in the PHP, PMA and SBI indices by 58.47 %, 47.4 % and 43.2 %, respectively.

   Conclusions. The obtained data allow us to conclude that hypoallergenic toothpastes « R.O.C.S. PRO Baby » and « R.O.C.S. PRO Junior Creamy Pudding » meets the safety and efficacy criteria for cleaning teeth and can be recommended to patients with a history of allergies aged 2 to 11 years for daily hygienic oral care.
Fundamento y metodología de una investigación sobre la familia desde el Centro de Orientación Familiar de la Universidad Pontificia de Salamanca
Authors: Tonini Zaccarini Franca
Published: January 2024

El valor universal de la familia es reconocido en cada contexto y
cultura. La familia desempeña un rol central en el contexto del Bie-
nestar Social (Welfare Statel. Constituye un punto de referencia indis-
cutible en el análisis inmediato y futuro de cualquier situación social
con los consiguientes resultados en los aspectos demográficos, econó-
micos, culturales, éticos y sociales. Se fundamenta la investigación
desde las perspectivas de la historia y teorías de la familia, la evolu-
ción de la familia en España (1975-2000!, las políticas y servicios para
la familia. Se tiene como referencia la Doctrina de la Iglesia en orden
a la vida, al matrimonio y la familia y para la institución de los Cen-
tros de Orientación Familiar. En este estudio se presenta el fundamen-
to y la metodología de la investigación familiar realizada en el ámbito
del Centro de Orientación Familiar de la Universidad Pontificia de
Salamanca. En él se presentan los pasos a seguir en la investigación,
que sigue el método cualitativo y cuantitativo, los objetivos y las hipó-
tesis que se plantean, la metodología utilizada, las técnicas de investi-
gación y el análisis del contenido. El estudio quiere presentar un ins-
trumento de investigación en el ámbito de las Ciencias Sociales y de
la Familia. Los resultados que se obtienen en su aplicación pueden ser
significativos en orden a la elaboración tanto de proyectos de funda-
ción de los Centros de Orientación Familiar y otros servicios para la
familia como para la elaboración de programas de intervención
Familia, Iglesia doméstica
Authors: Alburquerque Frutos Eugenio
Published: January 2024

El autor distribuye su aportación en cuatro partes: desde la teología
de la "Igl esia doméstica" tal como aparece en la Escritura, en el pensa-
miento de lo s Santos Padres y en el reciente Magisterio de la Iglesia uni-
versal y de la Iglesia en España, y ana liza a la familia como una 'pequeñ a
Iglesia' que rev ela el misterio de Crist o como comun idad qu e co nstruye
la Iglesia. Desd e aq uí pasa a considerar la dimensión sacramental de la
Familia en sus fundamentos y expresiones para terminar presentando la
ministerialidad de la familia cristiana.
Effect of Briquetting Pressure on the Physical Properties of Palm Oil Shell Briquettes and LDPE Plastic
Authors: Dalimunthe Yusraida Khairani , Satiawati Listiana , Widiyatni Harin , Anugrahadi Afiat
Published: January 2024

The purpose of this study was to analyze how the influence of briquette pressure on the physical properties of briquettes made from palm oil shell waste and LDPE plastic which includes the density value, elastic modulus and ultimate strength of the briquettes themselves. The method applied in this research is by varying the briquetting pressure, namely 80 N/m2, 70 N/m2, 60 N/m2, 50 N/m2, 40 N/m2 and 30 N/m2. The results obtained are the highest density value of briquettes, namely 808.71 kg/m3 produced from a pressure of 50 N/m2 and the lowest briquettes density value of 763.87 kg/m3 produced from a pressure of 80 N/m2, the highest briquette modulus of elasticity is 40 MPa produced from a pressure of 70 N/m2 and a pressure of 40 N/m2, then the lowest briquette modulus of elasticity is 20 MPa resulting from a pressure of 60 N/m2 and the highest ultimate strength value of briquettes is 3.402 MPa resulting from a pressure of 40 N/m2 and the ultimate strength value the lowest briquette is 2.813 MPa produced from a pressure of 80 N/m2.
Papel da Elastografia por Ondas de Cisalhamento na Avaliação da Rigidez Miocárdica nas Diversas Miocardiopatias
Authors: Fernandes Fabio , Santorio Nathalia Conci , Pereira Natália de Melo , Cafezeiro Caio Rebouças Fonseca , Alencar Neto Aristóteles Comte de , Bueno Bruno Vaz Kerges , Pereira Fernando Linhares , Chammas Maria Cristina
Published: January 2024

O ecocardiograma é fundamental para o diagnóstico e tratamento das doenças cardiovasculares. A avaliação da função diastólica do ventrículo esquerdo constitui um grande desafio, sendo utilizadas várias técnicas ultrassonográficas conhecidas, tais como o Doppler pulsátil do fluxo mitral, o Doppler tecidual e o strain miocárdico, com o objetivo de estimar de forma não invasiva a pressão de enchimento do átrio esquerdo. Apesar de amplamente disponível, essa abordagem possui várias limitações e não representa de fato as propriedades intrínsecas do músculo cardíaco. Nesse contexto, a elastografia cardíaca surge como uma forma de estimar a rigidez miocárdica de forma não invasiva, ao estudar a velocidade de propagação de ondas de cisalhamento no tecido cardíaco. A elastografia já é amplamente utilizada na avaliação da rigidez de outros tecidos, como tireoide, fígado e mama. No âmbito da avaliação cardiológica, essa técnica já foi empregada com sucesso em doenças como amiloidose cardíaca e cardiomiopatia hipertrófica. Este artigo visa revisar os principais conceitos associados a essa técnica promissora e expor as experiências publicadas de serviços nacionais e internacionais.
Zmarnowana szansa. O nowym-starym wydaniu dzieł Świętosława Orzelskiego
Authors: Kalinowski Emil
Published: January 2024

A wasted opportunity. On the new-old edition of Świętosław Orzelski’s works

Between 2019 and 2022, Włodzimierz Kaczorowski, a historian affiliated with Opole University, published a total of five volumes (with one volume being published twice) containing the works of Świętosław Orzelski, a sixteenth-century Polish parliamentarian, orator, and chronicler. It is, in fact, a reissue of the translations of these works made and published by Włodzimierz Spasowicz almost one hundred and seventy years ago with the addition of scholarly enhancements. Kaczorowski enriched the volumes with introductory notes, afterwords, extensive footnotes, and indexes. The article is a critical analysis of the result achieved, pointing out numerous errors, misrepresentations, and raising questions about the advisability of “revitalisation” of an outdated translation. The reviewer justifies the concern that issuing a source publication in such a form can do more harm than good to research on the history of Poland in the sixteenth century.
Tingkat Pengetahuan Masyarakat tentang Obat Tradisional di Banjar Pejeng Aji Tegalalang Gianyar
Authors: Wiradana Dewa Gde Adi , Dewi Agustini Ni Putu , Tangkas Suwantara I Putu , Megawati Fitria
Published: January 2024

Obat tradisional lebih banyak digunakan oleh masyarakat di pedesaan karena mudah didapatkan dan mudah diperoleh dengan harga yang relative murah, obat tradisional berkhasiat menyembuhkan berbagai macam penyakit dengan ramuan yang sudah dipercaya sejak turun temurun. Tujuan dari penelitian ini adalah untuk mengetahui sebrapa jauh tingkat pengetahuan masyarakat tentang obat tradisional di Banjar Pejeng Aji, Tegalalang, Gianyar. Penelitian ini merupakan jenis penelitian yang bersifat observasional yang bersifat deskriptif dimana Teknik pengumpulan data yang dilakukan menggunakan kuisioner. Penelitian ini dilaksanakan di Banjar Pejeng Aji, Tegalalang, Gianyar dengan jumlah populasi 254 kepala keluarga dan didapatkan sampel penelitian sebanyak 80 responden dengan rentang umur 17-65 tahun. Data yang diperoleh dari penelitian kemudian diolah dengan perhitungan persentase nilai dari jawaban responden. Hasil analisis data kuisioner yang diperoleh dari 80 responden menunjukan tingkat pengetahuan masyarakat di Banjar Pejeng Aji, Tegalalang, Gianyar berada di kategori Baik, dimana dari 80 responden yang menjadi sampel penelitian 75 responden (93,75%) responden memiliki pengetahuan baik, 5 responden (6,25%) berpengetahuan cukup dan 0 (0%) responden memiliki pengetahuan kurang
Kajian Terhadap Upaya Perlindungan Hukum Preventif terhadap Merek Dagang di Indonesia Berdasarkan Undang-Undang Nomor 20 Tahun 2016 tentang Merek dan Indikasi Geografis
Authors: Anshary Muhammad Ridha , Isradjuningtias Agri Chairunisa , Lekosono Arrum Budi
Published: January 2024

Pentingnya perlindungan hukum terhadap merek dagang di Indonesia tercermin dalam upaya preventif yang diatur oleh Undang-Undang Nomor 20 Tahun 2016 tentang Merek dan Indikasi Geografis. Penelitian ini menganalisis implementasi perlindungan hukum preventif tersebut dengan fokus pada pendaftaran merek. Metode analisis normatif dan pendekatan studi kepustakaan digunakan untuk mengkaji peran dan kendala dalam penerapan upaya preventif ini. Dalam konteks perlindungan merek dagang di Indonesia, pendekatan hukum preventif memiliki peran yang penting untuk mencegah terjadinya pelanggaran hak merek. Dengan mengacu pada Undang-Undang Nomor 20 Tahun 2016 tentang Merek dan Indikasi Geografis, upaya preventif dalam bentuk pendaftaran merek di Kementerian Hukum dan Hak Asasi Manusia (HAM) serta kewajiban pemegang merek untuk memenuhi persyaratan formal dan substantif menjadi landasan dalam memberikan perlindungan eksklusif terhadap merek. Melalui proses pendaftaran, pemegang merek mendapatkan kepastian hukum yang mengamankan hak eksklusifnya. Selanjutnya, implementasi praktis perlindungan preventif ini juga memerlukan peningkatan kualitas sumber daya manusia di lembaga terkait, serta penguasaan bahasa asing dan penerapan teknologi guna meminimalisir peluang terjadinya pelanggaran hak merek.
Antinutrients in Grain-Based Plant Drinks: Scoping Review
Authors: Strizhko Maria N.
Published: January 2024

Introduction: Plant-based beverages in the consumer market are positioned as an alternative to natural milk, including their nutritional value. Traditional milk raw materials are characterized by high nutritional value due to the optimal balance of components and their easy digestibility. However, the plant materials used in the production of drinks contain anti-nutritional substances. Anti-nutritional nutrients can limit the bioavailability of primary nutrients, leading to impoverishment of the human diet and a decrease in the nutritional value of food products.

Purpose: The purpose of this scoping review is a comprehensive analysis of various anti-nutritional factors in grain-based plant drinks with an assessment of methods and conditions for their inhibition.

Materials and Methods: This scoping review was conducted in accordance with the guiding principles of PRISMA-ScR. The databases SCOPUS, ScienceDirect, Google Scholar were used for article selection. The search was carried out for the period 2017-2022. As a result of the search, 77 publications from 35 countries worldwide were selected. The subject field review protocol was drafted and registered on the Open Science Framework website (https://osf.io/gcb3y).

Results: Out of 4432 selected publications, 77 met the inclusion criteria for the review. The analysis of the selected publications identified the main anti-nutritional substances present in grain drinks. These nutrients include phytic acid, phytates, lectins, saponins, oxalates, enzyme inhibitors. The authors of a significant portion of the publications (70%) devoted to the issue of antinutrients in the product, investigate this question within the technology of producing plant drinks. Trends such as negative and positive effects of antinutrients, methods of inhibiting anti-nutritional substances were identified. The obtained results allowed highlighting a new direction of non-traditional methods of inhibiting antinutrients, which had not been recorded before.

Conclusion: The main area of application of the research results can be the expansion of the scientific-practical database about antinutritional substances and the practical implementation of the proposed recommendations in the production cycle. The obtained data will significantly increase the nutritional value of grain-based beverages.
Development of enriched bakery products using biotransformation in starter cultures of protein-containing vegetable additives
Authors: Kosheleva Anna I. , Bogatyreva Tatyana G. , Belyavskaya Irina G.
Published: January 2024

Introduction: In the bakery industry, the key task is to produce quality products from diverse raw materials for healthy public nutrition. Technologies include the use of additives to enhance quality, biotransformation methods with starters, and the selection of enzymes and microorganisms. Biotransformation modifies the raw material, resulting in a product with superior taste qualities and nutritional value. The use of starters requires careful selection of microorganisms to optimize product quality.

Materials and Methods: The objects of research in the work were bakery products obtained by biotransformation of the studied plant raw materials, which was carried out by pure cultures of probiotic microorganisms - mesophilic homo- and heterofermentative lactic acid and propionic acid bacteria: Lactobacillus casei, L.plantarum, L.acidophilus, L.fermenti, L.brevis, Propionibacterium freudenreichii subsp. Shermanii. The work uses generally accepted standard methods for determining organoleptic and physico-chemical quality indicators of semi-finished products and finished bakery products. The indicator of resistance to microbiological spoilage of the developed bakery product was determined.

Results: Results: The use of defatted soy flour and sunflower protein as sources of plant protein has been justified. Based on comprehensive experimental studies, a rational method was identified for introducing defatted soy flour into the starter at 25% of the flour mass, which involves acid and enzymatic hydrolysis followed by biotransformation with a bacterial starter based on a composition of lactic acid microorganisms. Additionally, to increase the content of protein balanced in amino acid composition, as well as macro and microelements, vitamins, and antioxidants, a dosage of sunflower protein was selected at 10% of the flour mass in the product recipe.

Conclusion: A technology for enriched bakery products has been developed, and the nutritional value has been calculated. A comprehensive assessment of the quality of the finished products based on organoleptic and physico-chemical indicators has been conducted, and the shelf life has been determined.
Prospects for the use of probiotic organisms to develop alternative strategies for disinfection and prevention of infectious diseases
Authors: Kishilova Svetlana Anatolievna
Published: January 2024

Introduction: An important feature of microorganisms is the ability to adapt to adverse external influences, including the development of multiple antimicrobial resistance, leading to such negative consequences for humans as nosocomial infections, problems with cleaning rooms, medical and industrial equipment. The active use of chemical disinfectants for high-quality disinfection and cleaning has a number of disadvantages, including the risks of pathogens with new mechanisms of resistance to antimicrobial agents. The search for new, effective and safe antimicrobial agents as an alternative to chemical disinfectants is relevant. The use of probiotic strains of microorganisms, including lactic acid bacteria, in this capacity may be a promising area of research.

Objective: to analyze the literature data on studies of the potential of probiotic organisms, including lactic acid bacteria, to develop alternative disinfection and prevention strategies.

Materials and methods: This review of the subject field has been prepared based on the guiding principles of PRISMA-ScR. SCOPUS, Google Scholar, and RSCI databases were used. The works in Russian and English were considered, for the period 1995-2023.

Results: The review included 89 articles exploring the disadvantages of traditional disinfection methods and the search for alternative sanitation strategies. The description of various solutions for the introduction of probiotic purification methods is systematized – using bacteriophages, probiotic microorganisms of R. Bacillus and representatives of lactic acid bacteria as active agents.

Conclusions: A system of sanitary measures based on probiotic biodesinfectants, including lactic acid bacteria, can be included among the tools for countering pathogens, including their biofilms and forms with multidrug resistance. The introduction of a probiotic hygienic cleaning system, without having a negative impact on the environment, can increase the effectiveness of traditional hygienic preventive measures both in medical institutions and in production.
Enzymatic Method of Bioactive Peptides Production from Milk Protein Raw Materials: A Scoping Review
Authors: Kruchinin Aleksandr Gennadievich , Bolshakova Ekaterina Ivanovna
Published: January 2024

Introduction: For 14 years, interest in the use of dairy raw materials for the production of bioactive peptides (BPs) with antihypertensive, antioxidant and antidiabetic effects has been in a phase of rapid growth because of the need to prevent different diseases. Particular attention is being paid to enzymatic production method, as it allows for a targeted process of BP extraction with specified properties.

The  purpose of this scoping review was to summarize and systematize the experience of international research over the last 14 years in the field of FG as a method to extract BPs from milk protein substrates.

Materials and Methods: This scoping review was performed in accordance with the PRISMA-ScR guidelines. Scientific papers were searched in the Google Scholar database, because allows searching for scientific sources without restrictions on their format and type of scientific data presentation (book, dissertation, article), as well as includes scientific sources from other databases and performs relevance sorting.

Results:  The search identified 72 sources published between 2007 and 2021 in English. Included sources are devoted to hydrolysis by starter bacteria enzymes (SBE) - 50%  and by commercial enzyme preparations (CEP) - 50%.

Conclusion: There are a number of challenges that need to be addressed in order to increase the level of commercialization of BP production through directed hydrolysis. Creation of databases; building up the research base on co-fermentation by microorganisms and commercial enzymes; conducting PCR studies of microbial protease genes will increase the practical applicability of research and the validity of conducting more evidence-based in vivo and clinical studies.
Principles of formation of modular technologies of enteral nutrition products
Authors: Agarkova Evgenia Yuryevna , Belyakova Zinaida Yuryevna , Kondratenko Vladimir Vladimirovich
Published: January 2024

Introduction. Enteral nutrition products (EP) are represented on the market by a wide range of imported products, the technology and formulations of which are unique and are objects of intellectual property of foreign scientific centers. The application of a unified methodological approach to the design of EP products will make it possible to transfer this process from an empirical to a scientifically based plane.

Purpose of research is to create a rational set of technological solutions for the production of specialized EP products based on the principles of modularity, taking into account the cascade of technological qualitative and quantitative transformations.

Materials and methods. Digital matrices of patient conditions, EP products and ingredients were used as materials. The main research method was advanced digital profiling, taking into account the transformation of nutrients in the production process.

Results. According to the formed matrices of the chemical composition of imported EP products, the criteria relationships of their digital profiles and state profiles were established. Based on the principles of food combinatorics and digital profiling, an algorithm for an improved approach to the design and production of EP is proposed. A generalized modular technology for the production of EP products has been developed and its variability has been proved without changing the structure due to the combinatorial versatility of each of the set of models. The degree of its available combinatorial variability has been established, which is functionally dependent on the number of combinatorially manipulated ingredients, taking into account all possible k-component compositions. The required set of formulations of EP products is a set of solutions in terms of design with the possibility of determining the vector of tasks to be solved.

Conclusions. The obtained research results can be applied in the food industry in terms of unified production of specialized products.
Author Contribution in Manuscript Creation: Description and Announcement
Authors: Ryabova Anastasia Evgenievna
Published: January 2024

Introduction: The topic of publication ethics is increasingly important in scientific discussions, especially the issues of accurate and honest representation of author contributions in the creation of scientific articles.

Description of the CREDIT System: The contribution to authorship of an article is determined not only by participation in writing the text but also by the overall contribution of the participant in conducting the research itself. The CREDIT authorship model allows for precise tracking of each participant's contribution to the research project, describing various author roles, some of which may be independent, while others complement more significant roles.

Conclusion: Detailed coverage of the CREDIT taxonomy and the procedure for documenting author contribution enhances the transparency of scientific communication.
Analytical Assessment of the System for Confirming Compliance of Milk and Dairy Products with Mandatory Legal Requirements
Authors: Abdullaeva Larisa Vladimirovna , Bedretdinova Sophia Andreevna
Published: January 2024

Introduction: The safety and quality of dairy products produced and in circulation on the territory of the EAEU is ensured by compliance with legislation on technical regulation, sanitary, hygienic and veterinary safety. One of the important sections of technical regulation is the rules for confirming product compliance with mandatory legal requirements.

Purpose: The purpose of this review is analysis of the current legislative framework in the Russian Federation in the field of confirming compliance of milk and dairy products with the requirements of regulatory legal acts and systematization of the data obtained on the applicable forms assessing and confirming compliance of products in the Russian Federation.

Materials and Methods: As materials for the analytical study were used regulatory legal acts (hereinafter - RLA) in the field of technical regulation, sanitary, hygienic and veterinary safety of food products and raw materials. The documents were obtained on the official legal portals of the Government of the Russian Federation, the Eurasian Economic Commission, the Ministry of Agriculture of the Russian Federation, the Ministry of Industry and Trade of the Russian Federation, the Ministry of Health of the Russian Federation. As a research method, the analysis of the current legislation with the subsequent systematization of expert opinions on the law enforcement practice of the regulated rules for products confirming conformity, generalization and analysis of the most common arbitration situations in the raw milk and finished dairy products turnover at the stage of their compliance with mandatory requirements confirming (assessment) were used. The appeals and documents of the technical regulation and standardization services of dairy industry enterprises on the subject research field were also analyzed.

Results: Based on the regulated in RLA requirements for confirming (assessment) compliance of raw milk and dairy products, as well as based on the generalized results of a product manufacturers survey, have been established the conformity assessment schemes most often used by manufacturers. Taking into account the analysis and systematization of material on arbitration issues in confirming (assessment) compliance, recommendations are proposed for optimizing the process of confirming (assessment) compliance of raw milk and dairy products with the requirements of the legislation of the EAEU and the Russian Federation, including the feasibility of its updating.

Conclusion: According to the results of the research have been identified a number of problems in the field of confirming (assessment) of milk and dairy products compliance with the requirements of the RLA, which producers and regulatory authorities bodies in their professional activities, and appropriate solutions to these problems have been proposed.
Glyphosate, Phorate, and Monocrotophos Hazardous Pesticide Usage and Its Public Health Impact – An Empirical Analysis
Authors: Elakiya Sugumaran  , Prashanthy.M.R  , Bharathwaj  , Prabu.D  , Sunayana Manipal  , Rajmohan  , Vishali.M
Published: January 2024

Background: Pesticides are used extensively around the world and it has many health significance due to the usage of glyphosate,phorates, and monocrotophos that were mainly used as organophosphate pesticides in all the countries. Aim: To evaluate the countries which banned glyphosate, phorates, and monocrotophos hazardous pesticide usage and to assess the severity of risks caused by exposure of the pesticides.Methodology: This study was based on a review of scientific publications on usage of hazardous pesticides such as glyphosate, phorates, monocrotophos, and its impact on public health.Data were retrieved from the manual and electronic database by using the search engines (PubMed and google scholar). Results: European countries had banned glyphosate, phorate, and Monocrotophos pesticides within the year 2015 to 2019 whereas in India, two states namely Punjab and Kerala had banned glyphosate pesticides by the year 2018 to 2019, Phorates pesticides had banned in 2019, and monocrotophos pesticides were banned by the two states namely Punjab and Maharashtra in the year 2018. Glyphosate pesticides caused more impact on cancer and other health effects in the body in contrast to the other two pesticides had a lesser impact on cancer.Conclusion: Chemical pesticides can protect and improve farm productivity. However, their inimical and environmental health effects makes an inadequate long-term solution. Hence, to overcome this problem, there must be minimization of the usage of chemical pesticides and introduction of eco-friendly natural pesticides, which are easily accessible, low cost, and healthy method of a pest control system.
Comparative Evaluation of Disinfection on Elastomeric Impression Material using 2% Gluteraldehyde, Ultra Violet Radiation and Gaseous Ozone using Customised Disinfection Unit - An In-Vitro Study
Authors: Hetal Purohit  , Sweta Kale Pisulkar  , Seema Sathe Kambala  , Seema Sathe Kambala  , Surekha Dubey  Godbole  , Chinmayee Dahihandekar  , Rohit Ashok Mistry
Published: January 2024

Dental impressions is the preliminary step for any procedure and acts as a microbial source leading to contamination to the operator and lab technician. Hence, the disinfection of these impressions materials should be carried out unfailingly. The device was fabricated which helped in easy and effective disinfection.Aim: The aim of the study is to Compare and Evaluate the Efficacy of Disinfection on Elastomeric Impression material using 2% Gluteraldehyde, UV Radiation Disinfection and Gaseous Ozone. Objective: The efficacy of the disinfectants was compared based on the ability of the disinfectants in reducing the microbial colonies on the impression material. Methodology: Microbiological analysis was done and the colony forming units were evaluated and compared. The disinfection was done with a customized disinfection chamber which can be readily installed in the clinic and has multitudes of use other than disinfection. Result: Dry Gaseous Ozone as a disinfectant proved to be efficacious as compared to the other disinfectants. Conclusion: Dry gaseous ozone can be used effectively for disinfection of impressions without altering its dimensional stability. The customized disinfection unit is portable and can be readily installed in the clinic.
Mucormycosis in Post Covid Patient - A Case Report
Authors: Pathak Kush , Karadwal Asha , Nayak Prachi , Nayak Sushruth
Published: January 2024

Mucormycosis is considered to be a rare notorious fungal infection mainly affecting diabetics with or withoutketoacidosis & immunocompromised patients, with high mortality rate. Occurrence of Mucormycosis as animplication of Covid-19 has not yet been reported. We present a case of aggressive mucormycosis in a Postcovid-19 type-2 diabetic patient and aim to illustrate the possible Covid-19 effects on body and a dire needfor early diagnosis.
Age Estimation Using the Radiographic Visibility of the Periodontal Ligament in Mandibular Third Molars in Mysore Population- A Retrospective Study
Authors: Karthikeya Patil  , Mahima VG  , Poornima Chandran  , Bharathi Penumatsa  , Nagabhushana Doggalli  , Sanjay CJ
Published: January 2024

Objectives: This study was conducted to assess the reliability of age estimation using the radiographic visibility of periodontal ligament surrounding the roots of completely erupted mandibular 3rd molar.Materials and methods:Visibility ofperiodontal ligament was assessed in completely erupted mandibular third molars, in a sample of 135 panoramic radiographs, of which 55 belonging to females and 80 to males, from a Mysore population aged 18to 32 years. A classification of four stages based on the visual phenomenon of disappearance of the periodontal ligament of fully mineralized third molars was used. For each stage, mean, standard deviation, minimal & maximal age were assessed.Results:The relationship between age and stage of periodontal ligament had a statistical significance for both sexes.In this population, stage 1 can be used for predictability of age above 19 years and stage 3 for predictability of age above 23 years. No significant correlation exists between periodontal ligament visibility and gender of the individual.Conclusion:Thistechnique is advocated for determining age above 19 years as it is a relatively simple and reliable method. Differences exist in different ethnicities demanding specific population standards.