bluuebunny/crossref_metadata_2025 huggingface dataset:
Rivaroxaban in patients with atrial fibrillation: from research to real practice (based on REGistry of Long-term AnTithrombotic TherApy-2 (REGATA))
Authors: Kropacheva E. S. , Krivosheeva E. N. , Panchenko E. P.
Published: July 2021

Introduction. Despite the large evidence base for the use of rivaroxaban, cohort studies are interesting because shows the possibility of anticoagulant therapy in patients with high thromboembolic and bleeding risk and a burden of comorbidity in practice.

Aim: to evaluate the efficacy and safety of rivaroxaban therapy in patients with atrial fibrillation in prospective REGATTA registry.

Materials and methods. This study is a fragment of a single-center prospective REGATA registry (Registry of Long-term Antithrombotic Therapy (NCT043447187), conducted on the basis of the National Research Center of Cardiology of the Ministry of Health of the Russian Federation. 152 patients with high thromboembolic risk (median CHA2DS2-VASc = 4) received rivaroxaban therapy (median follow-up 1.5 years). The efficacy endpoint was the sum of cardiovascular complications (including cardiovascular death, ischemic stroke, and acute coronary syndrome). The safety endpoint bleedinds BARC types 2-5.

Results. The frequency of cardiovascular events (combining cardiovascular death, ischemic stroke and acute coronary syndrome) was 5.8/100 patient-years. The use of a “reduced” dose of rivaroxaban was an independent predictor of the development of fatal cardiovascular complications. The rate of major bleeding was 3.7/100 patient-years, and the rate of clinical relevant bleedings was 19.4 /100 patientyears. The predictors of major/ clinical relevant bleedings were chronic kidney disease with a decrease in creatinine clearance of less than 50 ml/min and the anamneses of major/ clinical relevant bleedings.

Conclusion. The main requirement for improving the safety of anticoagulants is follow up, focused in all changes in the cardiovascular and somatic status of the patient during treatment.
A case of successful surgical treatment of a ruptured giant aneurysm of the infrarenal aorta in an elderly patient
Authors: Zotikov A. E. , Khokonov M. R. , Eminov K. Kh. , Solovieva A. M. , Kozhanova A. V. , Ostapenko V. S. , Shchedrina A. Yu. , Chebotareva E. V. , Likalter D. L. , Molchanova A. Yu. , Aleksanyan L. A. , Tkacheva O. N.
Published: July 2021

Today, abdominal aortic aneurysm surgery is a fairly well-studied area of medicine. Nevertheless, some questions remain rather debatable. No clear criteria for giant aneurysms have been developed so far. The available foreign and domestic literature reports about 40 cases of surgical treatment of giant abdominal aortic aneurysms, 16 of which are cases of aneurysm rupture. Open surgery remains the method of choice in the treatment of giant aneurysms due to the pronounced technical difficulties of endovascular intervention. The authors present a case of successful surgical treatment of a giant aneurysm rupture in an elderly patient. The peculiarity of this patient's condition is the occurrence of aneurysm rupture after hospital admission. The patient refused surgical treatment for two years after aneurysm detection. On examination after admission, multispiral computed tomography revealed an aneurysm size of 101 mm. On the eve of surgery, pain syndrome in the left abdomen and tachycardia appeared. Aneurysm rupture was suspected and the patient was urgently admitted to the operating room. The surgery was performed under the conditions of machine reinfusion of autoblood. The patient underwent abdominal aortic aneurysm resection with linear prosthesis and retroperitoneal hematoma removal. The postoperative period had no peculiarities. On the 10th day after the operation the patient was discharged in satisfactory condition to the outpatient treatment. This clinical case demonstrates the possibility of successful surgical treatment of giant aneurysm rupture in elderly patients.
Risk assessment and prevention of venous thromboembolism among hospitalized patients: Results of the regional multicenter study
Authors: Sugraliyev A. B. , Aktayeva Sh. S. , Zhangelova Sh. B. , Shiller S. A. , Kussymzhanova Zh. M. , Tuganbekova S. K. , Sheriyazdan Zh. S. , Danyarova B. L. , Tsai V. E.
Published: July 2021

Introduction. Venous thromboembolism (VTE) is a major public health issue that is frequently underestimated. The primary objective of this multicenter study was to identify patients at risk for VTE, and to define the rate of patients receiving appropriate prophylaxis in the regions of Kazakhstan.

Materials and methods. Standardized case report forms were filled by trained medical doctors on one predefined day in selected hospitals. Data were analyzed by independent biostatistician. Risk of VTE was categorized according to Caprini score which was recommended by 2004 American College of Chest Physicians (ACCP) guidelines.

Results. 432 patients from 4 regions of Kazakhstan; 169 (39.10%) medical patients and 263 (60.9%) surgical patients were eligible for the study. Patients were at low (10%), moderate (19.2%), high (33.6%) and very high risk (37.3%) for VTE. The main risk factors (RF) of VTE among hospitalized patients were heart failure (HF), obesity, prolonged bed rest, and the presence of acute non-infective inflammation. From total number of hospitalized patients with RF with indications to VTE prophylaxis, 58.1% of patients received pharmacological prophylaxis and only 24.6% of them received VTE prophylaxis according ACCP. On the other hand, 23.5% patients with the risk of VTE but who were not eligible for it received pharmacological prophylaxis.

Conclusion. These results indicate the existence of inconsistency between eligibility for VTE prophylaxis on one hand and its application in practice (p < 0.001). Risk factors for VTE and eligibility for VTE prophylaxis are common, but VTE prophylaxis and guidelines application are low.
Elderly patient with atrial fibrillation and coronary risks
Authors: Yavelov I. S.
Published: July 2021

The incidence of atrial fibrillation (AF) and coronary heart disease (CHD) increases with age. Obviously, this is largely due to the coincidence of risk factors for the occurrence and progression of AF and risk factors for the occurrence and progression of atherosclerosis, including coronary atherosclerosis. Vitamin K antagonists, which are necessary for stroke prevention in patients with AF, are also reported to be able to prevent thrombotic complications of coronary atherosclerosis. No studies specifically designed to compare direct oral anticoagulants (DOACs) and vitamin K antagonists in the prevention of coronary thrombosis have been conducted, However, analysis of the results of randomized controlled trials ARISTOTLE, AUGUSTUS, PIONEER AF-PCI, REDUAL PCI, RE-LY and ROCKET AF indicates that in general DOACs are not inferior to warfarin in the ability to protect patients with AF from myocardial infarction and stent thrombosis. Accordingly, in stable patients with non-valvular AF (who have not suffered an acute coronary syndrome in the next 1 year or planned coronary stenting in the next 6 months) they can be used as monotherapy, without simultaneous administration of antiaggregants. Taking into account the data obtained in patients with sinus rhythm who recently had acute coronary syndrome in the randomized controlled trial ATLAS-ACS 2, as well as with stable atherosclerotic disease in the randomized controlled trial COMPASS, the greatest evidence base in the prevention of coronary complications has been accumulated with rivaroxaban. At the same time, the results of the COMPASS study, as well as analysis of daily medical practice indicate its additional benefits in patients with peripheral atherosclerosis.
IMPACTOS DA VENTILAÇÃO NÃO INVASIVA EM CRIANÇAS ASMÁTICAS INTERNADAS EM UNIDADES DE TERAPIA INTENSIVA E ENFERMARIAS: UMA REVISÃO INTEGRATIVA
Authors: APOLINÁRIA ALVES DA SILVA JUMA , OLIVEIRA ANDREZA IZIS DA SILVA , MAGALHÃES NETO ERY ALBUQUERQUE
Published: July 2021

Introdução: A asma é uma das doenças respiratórias crônicas de maior frequência na infância. A fisiopatologia das condições clínicas no estado asmático fornece uma sólida base fisiológica para o uso da ventilação não invasiva (VNI) em crianças. Objetivo: analisar a eficácia e segurança da VNI em crianças asmáticas internadas em ambiente hospitalar, assim como seus efeitos fisiológicos no sistema respiratório, através das evidências já existentes. Métodos: Foi realizada pesquisa nas bases de dados SciELO, Pubmed, Lilacs e na Biblioteca Virtual em Saúde (BVS), por artigos originais sobre asma e VNI em crianças. Em português, inglês e espanhol, publicados entre 2010 e 2020. Através dos descritores padronizados DeCS: “acute asthma”, “bilevel”,”pediatrics”, “continuous positive airway pressure”. Seguindo uma metodologia e critérios de inclusão e exclusão, de modo que 7 artigos foram selecionados. Destes 1 apresentou nível de evidência A (14,3%), outro B (14,3%) e 5 nível C (71,4%). Resultados: Seis artigos apresentaram desfechos positivos quanto ao uso da VNI nas disfunções respiratórias causadas pela asma. Os paciente apresentaram melhoras clínica como, otimização das trocas gasosas; menor tempo de estadia no hospital, menor índice de intubação, entre outras. Apenas 1 estudo indicou que a VNI é ineficaz e sem benefícios aparentes. Considerações finais: Os estudos indicaram que a VNI é uma boa opção terapêutica, segura e eficaz. Entretanto as informações atuais encontram-se limitadas, de pouca qualidade e controversas, sem uma padronização do seu manejo. Sendo necessário a realização de mais estudos randomizados que não deixe dúvidas quanto a sua utilização nesta população.
Emissões de Gases de Efeito Estufa Associadas às Dietas Alimentares no Brasil
Authors: Costa Gabriella Nunes da , Aguiar Danilo Rolim Dias de , Figueiredo Adelson Martins
Published: July 2021

O Sistema alimentar é uma das principais fontes de emissão de gases de efeito estufa (GEE). Como estas emissões variam de produto a produto, alguns autores afirmam que as dietas alimentares precisam mudar para que a produção de alimentos possa crescer com mínimo impacto ambiental. Suprindo a carência de estudos sobre as emissões de GEE associadas às dietas no Brasil, este trabalho visa examinar o impacto das dietas alimentares consumidas nas 26 capitais estaduais do país e no Distrito Federal nas emissões de GEE por parte de indivíduos de diferentes estratos de renda. Os resultados mostram que carne bovina e produtos lácteos são as principais fontes de emissões de GEE no Brasil e que as dietas dos nortistas e dos indivíduos de maior renda emitem muito mais. Como as dietas alimentares consumidas no país variam muito em termos de emissão de GEE e de valor nutricional, há viabilidade de se adotarem a dietas que tanto atendam às necessidades nutricionais dos indivíduos quanto reduzam as emissões de GEE.
Primera localización de un dormidero de milano real Milvus milvus L., 1758 en un eucaliptal en Álava
Authors: Sáenz de Santa María-Muniategui Antonio , Belamendia-Cotorruelo Gorka
Published: July 2021

During the 2020-2021 census to determine the wintering population of Red kite (Milvus milvus) in the Iberian peninsula by counting the number of communal roosts, one such roost was observed in a small reforested area of eucalyptus (genus Eucalyptus) in the northwest of the province of Álava (Basque Country-Spain). Although roosts located on this kind of arboreal substrate are rare, our observation suggests the hypothesis that Red kites will use eucalyptus if the atmospheric conditions are particularly adverse. Therefore, we propose that the distribution and winter ecology of Iberian breeding populations of Red kite be clarified with urgency, the study of which is hampered by the arrival of a multitude of conspecifics of central and northern-European origin in winter
Union and meet of an infinite number of type-2 fuzzy sets
Authors:   St. Petersburg State University, Baskov Oleg V.
Published: July 2021

The article examines the infimum and supremum of an infinite number of fuzzy numbers. It is shown that familiar properties of these operations, which are valid for real numbers, may apply to fuzzy numbers only under certain conditions. А formula for computing the infimum and supremum of any set of fuzzy numbers is provided. Since the union and meet of type-2 fuzzy sets are defined via the infimum and supremum of fuzzy numbers, all the results obtained are applicable to these operations as well.
Bending of a ribbed plate under complex loading
Authors:   The Bonch-Bruevich Saint Petersburg State University of Telecommunications, Goloskokov Dmitry Р. , Matrosov Аlexander V. ,   St. Petersburg State University
Published: July 2021

The article considers the problem of a rectangular plate, supported by a cross system of stiffening ribs, bending. In addition to the transverse load, the plate is subjected to forces in its plane, transmitted through the ribs. Аn analytical solution to the boundary value problem for the resolving differential equation with respect to the normal deflection of the plate, describing the deformation of a rectangular plate supported by stiffeners, is obtained. The solution is presented in the form of series in combinations of regular and special discontinuous functions, which converge quickly and lead to a simple computational algorithm. The influence of the ribs is taken into account in the equation in the form of additional terms containing factors with a delta function. This approach allows us to get rid of a number of assumptions regarding the interaction of the plate with its reinforcing elements. The use of the apparatus of generalized functions when modeling objects of this type simplifies the boundary conditions (there are no conditions for conjugation of various structural elements), but at the same time the differential equations become more complicated. The problem is reduced to the so-called partially degenerate equations. Development of analytical methods that allow obtaining exact solutions of differential equations of this type, and their introduction into computational practice, is one of the urgent tasks of the mechanics of objects with disturbed regularity.
Mathematical modeling of triode system on the basis of field emitter with ellipsoid shape
Authors:   St. Petersburg State University, Egorov Nickolay V. , Vinogradova Ekaterina M. ,   St. Petersburg State University
Published: July 2021

In this paper the mathematical modeling of the triode emission axially symmetric system on the basis of field emitter is considered. Emitter is an ellipsoid of revolution, anode is a confocal ellipsoidal surface of revolution. Modulator is a part of the ellipsoidal surface of revolution, confocal with the cathode and anode surfaces. The boundary-value problem for the Laplace's equation in the prolate spheroidal coordinates with the boundary conditions of the first kind is solved. The variable separation method is applied to calculate the axisymmetrical electrostatic potential distribution. The potential distribution is represented as the Legendre functions expansion. The expansion coefficients are the solution of the system of linear equations. All geometrical dimensions of the system are the parameters of the problem.
Investigation of the frequency properties of a standard linear body
Authors:   St. Petersburg State University, Tregubov Vladimir P. , Egorova Nadezhda K. ,   St. Petersburg State University
Published: July 2021

It is known that the Кelvin-Voigt model does not describe stress relaxation, which is observed along with elastic properties in many polymers and biomaterials. In this regard, the standard linear body model is used to describe the properties of these materials. Studies of its properties were mainly limited to the study of its reaction to an instantaneously applied load, as well as to the determination of the time and nature of stress relaxation. Аt the same time, the frequency properties of the standard linear body remained unexplored. In this regard, an analysis of its frequency properties was carried out, which made it possible to study its behavior under vibration exposure. Оn the basis of the equation of motion, the amplitude-frequency response (АFC) was constructed, and its peculiarity was revealed, which consists in the fact that an increase in the damping coefficient leads to a decrease in the maximum value of the АFC only to a certain value greater than one. А further increase in the damping coefficient leads to an increase in the maximum frequency response up to infinity at a frequency that should also be considered resonant. Thus, the frequency response of a standard linear body always has a maximum. The subsequent increase in the damping coefficient leads to the tendency of the maximum frequency response to zero at infinity.
Lyapunov - Кrasovskii functionals for homogeneous systems with multiple delays
Authors:   St. Petersburg State University, Аlexandrova Irina V. , Zhabko Аlexey Р. ,   St. Petersburg State University
Published: July 2021

In this article, explicit constructions of Lyapunov - Кrasovskii functionals are proposed for homogeneous systems with multiple constant delays and homogeneity degree of the right- hand sides strictly greater than one. The constructions are based on the Lyapunov functions suitable for the analysis of corresponding systems with all delays equal to zero. The letter systems are assumed to be asymptotically stable. It is proved that the proposed functionals satisfy the conditions of the Кrasovskii theorem, and hence it allows us to establish the asymptotic stability of the trivial solution for arbitrary values of delays. The functionals are applied to the estimation of the attraction region of the trivial solution.
Mathematical model of joint optimization of programmed and perturbed motions in discrete systems
Authors:   St. Petersburg State University, Kotina Elena D. , Ovsyannikov Dmitri А. ,   St. Petersburg State University
Published: July 2021

А new mathematical model for the optimization of discrete systems is constructed in the article. The program motion and the ensemble (beam) of perturbed motions are investigated. In this case, the authors consider the joint optimization of smooth and non-smooth functionals defined on the program and perturbed motions. The variation of the functional and the necessary optimality conditions are provided. The developed mathematical technique allows solving non-standard control and optimization problems in various fields of science and technology.
Influence of multisite calibration on streamflow estimation based on the hydrological model with CMADS inputs
Authors: Song Yongyu , Zhang Jing , Lai Yuequn
Published: July 2021

Due to the spatial heterogeneity, the hydrological model calibration results only at the total outlet of the basin may not represent the whole basin. To more accurately simulate the historical streamflow process within the Qujiang River Basin, we set up three calibration strategies (single-site, S1; multisite simultaneous, S2; and multisite sequential, S3) for four hydrological stations based on the SWAT (Soil and Water Assessment Tool) model driven by CMADS (China Meteorological Assimilation Driving Datasets for the SWAT model). In addition, the implications of these calibration issues are extended to future streamflow projections using multimodel ensemble data in CMIP6 (Coupled Model Intercomparison Project Phase 6). In the model calibration phase, the SWAT model achieved very satisfactory results in the study area. Compared with S1 and S2, S3 can effectively improve the accuracy of streamflow simulation of stations within the basin and reduce the simulation deviation. Especially at the daily scale, the average NSE values of the four stations with S3 increased by 0.26 and 0.07, and the overall deviation decreased by 0.25 and 6.43%, respectively. Parameter sensitivity analysis also shows that spatial heterogeneity can be more adequately considered when using S3 to calibrate the model. As for the results of future streamflow projection, when using the S3, the average annual streamflow of four stations in the three climate scenarios from 2021 to 2050 is about 44.21, 130.00, 321.55 and 713.24 m3/s, respectively. Correspondingly, the use of S1 and S2 would bring certain risks to future water resource management.
A multi-objective optimization method based on NSGA-III for water quality sensor placement with the aim of reducing potential contamination of important nodes
Authors: Jafari Hamideh , Nazif Sara , Rajaee Taher
Published: July 2021

One way to mitigate the risk of consumption of contaminated water in water distribution networks is optimal placement of the quality sensors. A considerable challenge in this respect is the significance of contamination at a junction. Beside the population affected and the volume of the contaminated water consumed, importance of each junction is a parameter that must be taken into account in placing the sensors. This parameter directly concerns the service provided by each junction as well as the sensitivity and social consequences of junction contamination. The present study defines a new objective function for minimizing the effect of junction contamination with respect to its importance. Using a robust approach, this study applied the NSGA-III algorithm to solve a 5-objective problem. The algorithm was tested on a hypothetical network and a benchmark network and the Pareto response was selected for each scenario based on the slope of the different points. The proposed method suggested 12, 12, and 11 sensors for the three scenarios in the hypothetical network. The results show that sensor placement by this method yielded good performance in comparison with the other solutions presented in a benchmark network.
Effect of the famine phase length on the properties of aerobic granular sludge treating greywater
Authors: Rojas-Z U. , Fajardo-O C. , Moreno-Andrade I. , Monroy O.
Published: July 2021

Sequencing batch reactors (SBR) treating high-strength greywater need an aerobic granular sludge (AGS) with good properties, such as a low sludge volume index (SVI) and high settling velocities and substrate uptake rates to yield short settling and aeration stages. To promote the formation of stable granular sludge, the length of the famine phase could be a key factor. In this regard, the effect of the duration of this variable on the AGS properties was assessed by comparing a gradual versus an abrupt reduction of the famine phase in two SBR treating greywater. The initial average famine phase of 3.3 h was gradually reduced to 0.3 h over 20 weeks in one reactor, and abruptly in another one. This condition induced filamentous outgrowth, as well as the deterioration on the properties of the sludge; the effect was more accelerated when the famine periods were abruptly shortened. In both cases the reduction on the famine periods induced increased organic loading rates, which led to degranulation events when it was higher than 2.5 g-chemical oxygen demand g-volatile suspended solids−1 d−1. Afterwards, the biomass adapted to this situation, by forming new small-filamentous aggregates with similar SVI to that of the stable AGS formed with the longest famine period.
COMMON INSTRUCTIVES IN NETWORK DISCOURSE
Authors:   Astrakhan State University, DANILE DARIA D.
Published: July 2021

The article devoted to speech genre «common instructives» in network discourse. They are understood as various types of advice. The main feature is the addresser desire of providing assistance to the addressee. The functional characteristics of the instructives are related with the following features: 1) the direction of the illocutionary act; 2) obligatory or non-obligatory of the expected action implementation; 3) participants attitude to the recommended action in the communication; 4) tone of utterance. The areas of instruction dissemination are wide and varied. They are often found in the form of requirements, regulations, instructions, and warnings. They are characterized by the asymmetric top-down relations model, in which the addressee superiority is found, but at the same time the actions of addresser are independent. Instructives can illustrate a positive or a negative addressee reaction i.e. they can be accepted or not. Instructives in the web often merge with entertaining genres of playful sayings such as absurd or "harmful" advice.
FUNCTIONING OF MEDICAL TERMS IN CONSCIOUSNESS OF THE FIRST-YEAR FRENCH-SPEAKING STUDENTS
Authors:   Astrakhan State Medical University, LUKOYANOVA TATIANA V. , KASIMTSEVA LYUBOV M. ,   Astrakhan State Medical University
Published: July 2021

He problem of interaction between language and society is more and more relevant in the modern world. Changes of the world have influenced the discourse in various spheres of communication. Moreover the progress of medicine has led to changes in the system of medical terms, and, consequently, to difficulties in understanding of terms in the ordinary consciousness. A person always wants to understand other people and to be understood by them. So it is the main goal of communication. The article deals with the issue of the functioning of medical terms in the minds of first-year French-speaking students. First-year stu- dents have the ordinary consciousness. Medical terms, which are studied by them (first-year students), function in the ordinary consciousness in incorrect form. It's because they are based on associations, feelings which the person has during the process of cognition, and, therefore, they must be interpreted. During the process of learning, there is a need to clarify the personal meanings that medical students have in regarding to special terms. In this article the author gives the results of the research concerning the French-speaking students' knowledge of medical terminology. The author gives examples of the perception and rethinking of medical terms based on common knowledge and examines the formation of scientific knowledge to develop the language of medicine in the consciousness of students and its competent use in the future.
TRANSITION PHENOMENA IN THE SUPPLY SYSTEM WITH HOMOGENEOUS MEMBERS
Authors:   Oryol State University named after I.S. Turgenev, LOGACHEVA ANNA A.
Published: July 2021

The article deals with transitional phenomena in the system of sentences with homogeneous members. The purpose of this work is to describe syncretic cases in the structure of sentences with homogeneous semantics. Sentences taken from the language of fiction were the subject of this study, which was carried out within the framework of the structural and semantic direction. With the help of structural and semantic methods, the main characteristics of sentences with homogeneous members in a theoretical aspect are described, and syncretic cases that cannot be qualified unambiguously are shown. In the course of the study, it was found that the phenomena of transitivity are characteristic of sentences with homogeneous members. In the syntax of the language of lyrics, the processes of transition are manifested more vividly than in the language of fiction. This is due to the fact that the linguistic semantics of a poetic work becomes complicated under the influence of the informativeness, rhythm, rhyme and melody of the poetic line. The results of the study outline possible ways of understanding sentences with homogeneous semantics in the syntactic system of the language, and can also be used in the linguistic analysis of the text.
TECHNICAL TERMINOLOGY TRANSLATION IN ENGINEERING CONTEXT
Authors:   Siberian Federal University, STUPINA TATYANA V. , FILONCHIK OLGA A. ,   Siberian Federal University
Published: July 2021

The paper considers special aspects of technical translation and peculiarities of engineering terminology interpretation in English-Russian language pair correlation. Problems of adequate translation of general and specialized words, vector of compound lexical elements in engineering context, text production and inversion in the English and Russian languages, transformations in technical translation with compression and addition techniques are analysed. Preference of building English engineering terms with common words, mainly the "noun-noun" group is highlighted.
THE STRATEGY OF SELF-PRESENTATION WITHIN THE SUBGENRE OF THE ENGLISH-LANGUAGE OLYMPIC DISCOURSE “PORTRAIT INTERVIEW-SKETCH”
Authors:   Astrakhan State University, TORBIK ELENA M.
Published: July 2021

The article is devoted to the study of the subgenre "portrait interview-sketch", which has not been studied within the English-language Olympic discourse. The analyzed materi- als were published on the official website of the US Olympic team during the 2018 Winter Olympics. The means of implementing a self-presentation strategy designed to create a positive image of athletes-members of the Olympic team, which can be used as the basis for representing the image of the country as a whole, are identified and illustrated at the lexical, phraseological, morphological and semantic levels. The current research has demonstrated the disengagement of this genre from politics.
THE TERMS-VERBS IN CONTEMPORARY MEDICAL TEXT
Authors:   Astrakhan State University, VEKLICH MARINA V.
Published: July 2021

The article presents a fact-based study of the verbalization of medical knowledge, verbal nomination as one of the ways to create a Russian medical dictionary. The linguistic materials collected during the research indicate the ability of the verb to terminate concepts. Verb-terms, in contrast to noun-terms, nominate specific processes, phenomena. Verb terms are included in word-formation nests along with noun terms. Verb terms fall into two groups: 1) branch verbs and 2) common verbs. The first group unites verbs characteristic of the medical field of knowledge, the second group includes verbs, the terminological nature of which is manifested in the composition of a phrase with a dependent noun-term. In such verb-nominal phrases, the verb either expands the meaning, or concretizes the existing one. Verb terms are used mainly in those branches of medicine that are associated with a specif- ic action (for example, surgery). Verb terms have the same grammatical categories as verbs of the general literary language. The results obtained can be used for further research on the cognitive properties of verbs-terms based on new sources.
CONCEPTUALIZATION AND CATEGORIZATION OF SIMPLEX DEVERBAL NOUNS WITH -ER
Authors:   Pyatigorsk State University, AVETISYAN MILANA I.
Published: July 2021

The article reveals the conceptualization and categorization peculiarities of simplex deverbal nouns with -er. The research is based on the extensive empiric material and is carried out at the interface of the structural and cognitive linguistics theories. The latter are represented by the methods of semantic decomposition, structural and cognitive-semantic analysis along with the method of conceptual modeling. The carried out analysis has allowed the author to elucidate that the lexis stratum under study falls into the subcategories with the cognitive basis expressed via the concepts “animate doer’, “instrument”, “event” and “purpose location”. Having processed the empirical data the author highlights and systema- tizes the integral and differential parameters which underlie the meaning of the -er nominatives from the above mentioned categories. It has also been found out that the category “an- imate doer” has the most complicated conceptual structure and serves as a feeder for the other categories. These observations indicate the anthropocentricity of the -er deverbals semantics.
ARTISTIC PERSONALITY "FRONT" LYRICS OF B. SHAKHOVSKY
Authors:   Astrakhan State University, BOROVSKAYA ANNA A. , BYCHKOV DMITRY M. ,   Astrakhan State Technical University
Published: July 2021

This article analyzes the corpus of lyric poems by B. Shakhovsky, dedicated to the Great Patriotic War. According to the observations of the authors of the study, the poet's «war» poems are works with a narrative-prose organization of the text. The article proves that they are characterized by plot and factual nature. It is concluded that this feature is explained by the general trends in the development of Soviet poetry in the 1940-1960s, as well as by the fact that the heroics of the time dictated the need to appeal not to the individual, but to the mass consciousness, requiring an expansion of the spectrum of psychologically effective artistic forms. This study shows the mechanisms of epization of the lyrics, analyzes the syncretic forms of the lyric epic. The authors of the article conclude that the style of «military» poems by B. Shakhovsky is expressive, aphoristic, declarative, rhetorical.
COMPARATIVE STUDY OF THE IMAGE OF WOLAND IN THE NOVEL “THE MASTER AND MARGARITA” BY M. BULGAKOV AND THE ISLAMIC GNOSTIC APPROACH TO THE CONCEPT OF “DEVIL”
Authors:   University of Tehran, KARIMI-MOTAHHAR JANOLAH , AREZOO ASHTIJOO ,   University of Tehran, KAZIEVA ALMIRA M. ,   Pyatigorsk State University
Published: July 2021

The problem of evil and the devil as a representative of evil has long existed in the religion and culture of different nations. This article attempts to find similarities on this issue in the novel “The Master and Margarita” by Mikhail Bulgakov (1891-1940) and in the approach of some Islamic Sufis, such as Mansur al-Hallaj (858-922) and Ain al-Kuzat Hamadani (1098-1131), etc. What is common in the image of the devil in the pages of the novel of a Russian writer of the twentieth century, a native of the Orthodox environment, and in the texts of medieval Islamic mystics? Common to representatives of these different cultures and eras is the desire to comprehend the problem of the existence of evil in the world and its embodiment in the form of the devil. The similarity is in the fact that the problem of evil and its bearer is posed by Bulgakov and Sufis both in a purely religious context, and in philosophical, Gnostic. In both Islam and Christianity, the devil (“Satan”, “Shaitan”) is the main opponent of the heavenly forces, which is the highest personification of evil and pushes a person on the path of spiritual death. In addition to the religious context, the devil is seen as the result of a Gnostic and mystical approach by different thinkers in the form of an artistic image.
THE OCCUPANTS AND THE POPULATION OF NORTH-WEST RUSSIA DURING THE GREAT PATRIOTIC WAR
Authors:   Peter the Great St. Petersburg Polytechnic University, KRASNOZHENOVA ELENA E.
Published: July 2021

The war of Germany against the USSR was based on the idea of expanding the "living space" of the German nation, capable of using the resources of the occupied territories of the Soviet republics for the benefit of its own development. The population of the countries destined for conquest must feed the German economy with man power resources, the natural reserves of their former territories will provide the economic needs of the German army and the entire German people. The most important tool for the economic use of the occupied territories was the tax system, the export of production equipment, property of organizations and citizens. For staffing industrial production in the occupied territories, labor exchanges were created, distributing the civilian population to work at local enterprises. The occupation caused enormous damage to the population, economy and economy of the North-West of Russia. The number of the local population, which was destroyed in concentration camps, was subjected to robberies and terror, and was mobilized for defensive and other work, significantly decreased. The population experienced constant hunger, only those who were involved in compulsory work in production received the minimum supply. A significant number of able-bodied citizens of the occupied regions of the North-West were sent to forced labor in Germany. The violent deportation of the population to Germany was accompanied by unprecedented cruelty and brutal reprisals. In the face of intensified repression, the process of mass entry of the rural population into partisan detachments began.
ACTUAL ISSUES OF ETHNOPOLITICAL EXPERTISE AND ETHNOPOLITICAL PROCESSES’ MONITORING (BASED ON THE MATERIALS OF THE KUBAN AND CRIMEA REGIONS)
Authors:   Kuban State University, BARANOV ANDREW V. , ROGOCHAYA GALINA P. ,   Kuban State University, SAVVA ELENA V. ,   Kuban State University
Published: July 2021

The authors of this article clarify the subject of ethnopolitical expertise and monitoring of ethnopolitical processes, their main thematic topics, draw distinctions with related branches of scientific practice-oriented knowledge, assess the current status of ethnopolitical expertise and monitoring of ethnopolitical processes in Russia in the context of improving federal legislation. The authors argues that it is unacceptable to narrow the subject of ethnopolitical expertise. The authors evaluate the experience of ethnopolitical expertise implementation and monitoring of interethnic and confessional relations, ethnic policy in the Krasnodar territory, the Republic of Crimea and Sevastopol city (2014-2020). Factors and indicators of monitoring of interethnic and confessional relations are evaluated on the example of the studied regions. Measures are proposed to improve the quality of ethnopolitical expertise in the aspects of organizing its interaction with state authorities and mass media, providing evidence and publicity. The authors argue the need to create permanent expert structures and networks of interaction between professionals and the state authorities, the education system, political parties and public organizations, and the mass media.
STRATEGIES FOR SHAPING AND BROADCASTING THE IMAGE OF POLITICIANS ON THE INTERNET
Authors:   Astrakhan State Polytechnic College, KURKEMOVA EMILIA T.
Published: July 2021

The article proposes a study of strategies for forming the image of politicians through Internet technologies. The main existing methodological approaches to studying the issues of forming a political image using modern information technologies are considered. A typology of strategies for the formation of a politician's image on the Internet is proposed, based on the priority of using the Internet. The strategies of preferential and auxiliary use of the Internet and new information technologies for the formation of the image of a politician are characterized. The strategy of the predominant use of Internet technologies for the formation of the image turns out to be the most promising for opposition politicians. Incumbents and representatives of the ruling party are interested in more diversified approaches to the formation of a political image and are using a strategy of auxiliary use of Internet resources. The degree of importance of new information technologies in solving problems of forming and promoting a political image depends, inter alia, on the political guidelines of the audience. The question of the applicability of a common typology of strategies for the formation of a political image to the process of forming a political image on the Internet is considered. The issue of measuring the effectiveness of individual strategies for the formation of a political image on the Internet remains insufficiently studied in modern science.
REGIONAL IDENTITY IN THE STUDENTS' CONSCIOUSNESS IN SIBERIAN FEDERAL DISTRICT
Authors:   Altai State University, KAZANTSEV DMITRY A. , KACHUSOV DMITRY A. ,   Altai State University
Published: July 2021

At the moment, the question of correlation between national and regional identification and their impact on the Russians' consciousness stays acute. The peculiarities of historical development, the aspects of the government policy in Russia and global crisis of identity do influence the process of selfidentification among the Russian citizens, sometimes at the expense of the regional level. Nonetheless, regional identity is still an important piece of social-cultural puzzle of the Russian regions, both national and administrative-territorial. The indications of regional identity, at least partial, or as one of the few identities, can be found among senior students. To find the markers demonstrating that, the mass polling of the students was performed in schools of the Siberian Federal district. The results of this research allows us to detect different types and nature of national, regional, local identity among students from different subjects of the Russian Federation, as well as to define the local specifics in question of social-political selfidentification.
RETHINKING POVERTY: SOCIAL DIMENSION OF RESPONSIBLE DEVELOPMENT CONCEPT
Authors:   Primakov National Research Institute of World Economy and International Relations, Russian Academy of Sciences, BARDIN ANDREI L. , SIGACHEV MAKSIM I. ,   Primakov National Research Institute of World Economy and International Relations, Russian Academy of Sciences, KUTERGIN VASILIY A. ,   International Child Center “Artek”
Published: July 2021

This article is an attempt to structure the discourse on poverty and inequality, as it appears in the works of renowned philosophers, economists and sociologists. Globally, the problem of poverty and inequality remains unsolved and is aggravated by global crises and, most recently, the COVID-19 pandemic, posing a threat to social stability. The authors point out that, in the short and middle term, solution to this problem under the current paradigm of development seems highly unlikely. The sustainable development paradigm, which has been globally recognized, has numerous strong points; however, it also has a number of internal contradictions, especially regarding the social aspects of development. Therefore, a more socially oriented model of development could help overcome these drawbacks. With this goal in mind, the authors introduce the concept of responsible development, and dwell on the history of thought on the problem of poverty and inequality. This review could serve as a basis for further research of social policy, as well as for development of analytical and policy tools that pay more attention to the moral and ethical dimension of social issues.
THE RUSSIAN PEOPLE AND THE STATE: THE POLEMIC OF V. V. ROZANOV AND N. A. BERDYAEV
Authors:   Lomonosov Moscow State University, KARTUNOVA ANGELINA D. , PUCHNINA OLGA E. ,   Lomonosov Moscow State University
Published: July 2021

V. V. Rozanov (1856-1919) and N. A. Berdyaev (1874-1948) were original Russian philosophers and publicists, despite the age difference, they were familiar both personally and with each other's works. Comments on each other's ideas are scattered through various works of philosophers, but there was also a brief period of active mutual polemics in journalism. Despite the contradictory assessment of mutual creativity and the specifics of each person's religious worldview, they addressed common themes. Russian thinkers pointed out the specific features of the Russian national character-the priority of the spiritual principle over the material, the compliance and sacrifice of the Russian person, a special attitude to social and political activity, but each of them interpreted this specificity in their own way. Rozanov and Berdyaev expressed similar opinions about the role and functions of state power in society, in their opinion, it should first of all protect people from arbitrariness and reduce the amount of evil in the world. Their political ideals were also close - as conservative philosophers, they preferred the monarchy. However, Rozanov and Berdyaev had different views on the tasks and goals facing the Russian people, and also had different opinions on the causes and consequences of the First World War for Russia.
Nikomedia Eserine Yeni Bir Bakış
Authors: Arlı Yaşar
Published: July 2021

Kocaeli Arkeoloji Müzesi’nde korunan kadın başının tarihlendirilmesi konusunda R. Özgan ile aynı görüş paylaşılmamıştır. Nikomedia’dan ele geçen fakat kentteki buluntu yeri bilinmeyen ve herhangi bir yazıtla da desteklenemeyen Nikomedia eseri, özel portre olarak tanımlanmıştır. Tarihlendirme konusunda ise R. Özgan, Geç Traianus dönemini önermiş olsa da eserdeki stilistik özellikler bu döneme özgü değildir. Kuaförlük modasının Flaviuslar Hanedanlığı dönemine ait olduğu portre baştaki idealize özellikler eseri, bu dönem ve Traianus dönemi portrelerinden ayırmaktadır; çünkü Flaviuslar Hanedanlığı’ından, Traianus döneminin sonuna kadarki süreçte portresi yapılan kişilerin karakteristik özellikleri idealize etkilerden uzak aktarılmıştır. Hadrianus döneminde ise imparatorun Grek hayranlığıyla portre sanatında yeni bir sanat akımı doğmuştur. Klasizme öykülenme olarak da tanımlanan bu süreçte portresi yapılan kişilerin karakteristik özellikleri güçlü idealizm etkisi altında yontulmuştur. Kadın başında da takip edilebilen bu stilistik özellikler, Nikomedia eserinin tarihlendirmesinde oldukça önemlidir. Bu yüzden de Geç Hadrianus dönemi özelliği olan göz bebeği ve irisin de işlenmediği portre baş, Erken Hadrianus döneminde Domitia Longina’nın I. tip portrelerinden esinlenerek yontulmuş özel bir portre olmalıdır.
Amelioration of Experimental Hepatotoxicity in Rats by Portulaca
oleracea Linn. from Kashmir Himalaya
Authors: Dar Mohd A. , Mir Prince A. , Masoodi Mubashir H. , Alqahtani Ali S. , Siddiqui Nasir A. , Ahmad Bahar
Published: July 2021

Background:

Traditionally, Portulaca oleracea Linn. is used for treating abscesses,
dysentery and liver diseases. In addition, recent studies have reported its efficacy as an analgesic,
as neuroprotective, anti-inflammatory, bronchodilatory, and anticancer agent, besides antioxidant,
wound healing and other important pharmacological actions.

Aim and Objective:

For curing liver diseases, Chinese use juice from the fresh leaves of Portulaca
oleracea Linn. Hence, to prove this claim, an in-vivo hepatoprotective study of extracts from
Portulaca oleracea Linn. against carbon tetrachloride hepatotoxic rats was carried out.

Methods:

The in-vitro antioxidant activity by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free
radical scavenging assay and hepatoprotective activity of extracts of Portulaca oleracea Linn. was
assessed against the carbon tetrachloride-induced toxicity rat model.

Results:

The extracts of Portulaca oleracea Linn produced concentration-dependent percentage
inhibition of 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical and most significantly, by
methanol extract. Among the extracts, methanol extract showed a significant decrease in Serum
glutamic oxaloacetic transaminase (SGOT), Serum glutamic pyruvic transaminase (SGPT),
alkaline phosphatase (ALP) levels and a significant increase in total protein (TP) levels against
carbon tetrachloride-induced liver toxicity

Conclusion:

From the results obtained, it was concluded that methanol extract of Portulaca
oleracea Linn. possesses significant DPPH free radical scavenging and hepatoprotective potential.
circPUM1 Activates the PI3K/AKT Signaling Pathway by Sponging to
Promote the Proliferation, Invasion and Glycolysis of Pancreatic Cancer
Authors: Huang Fei , Tang Di , Chen Yang , Liu Yuhong , Tao Qiang , Fan YouWen , Ma Chao , Li Dong
Published: July 2021

Background:

Our study seeks to obtain data to assess the impact of circPUM1 on pancreatic
cancer (PC) and its mechanism.

Methods:

The expression of circPUM1 and miR-200c-3p in PC and normal tissues and PC cell lines was
collected and detected, and subsequently dual-luciferase assay-based verification of the binding site of
the two was carried out. After interfering with circPUM1 expression in MIAPaCa-2 and PANC-1 cells,
cell proliferation, viability, apoptosis rate, invasion ability, glucose consumption, and lactate production
were measured by MTT, colony formation, flow cytometry, Transwell assays, and glucose and lactate
assay kits. Additionally, western blot was utilized for assessing PI3K/AKT signaling pathway-related
proteins. From the results, highly expressed circPUM1 and miR-200c-3p in PC tissues and cells were
proved.

Results:

Down-regulation of circPUM1 expression significantly inhibited cell proliferation, cell viability,
invasion and glycolysis, while increasing the apoptosis rate. Down-regulated circPUM1 led to the
inhibition of the PI3K/AKT signaling pathway activity in PC cells; while up-regulated circPUM1 increased
its activity. Further experiments revealed that down-regulation of miR-200c-3p expression reversed
the inhibitory effect of lowly expressed circPUM1 on PC cells.

Conclusion:

In summary, circPUM1 activates PI3K/AKT signaling pathway by sponging miR-200c-3p
and promotes PC progression.