bluuebunny/crossref_metadata_2025 huggingface dataset:
SEMANGAT BERSAMA NESCAFE DALAM FOTO ILUSTRASI
Authors: Aryanti Widya Jidan , Aurelia Silviana Amanda , Novianti Erlina
Published: January 2024

Sejarah perkembangan kopi di Indonesia dapat dimulai sejak abad ke 16 pada tahun 1696, India mengirimkan bibit kopi Yaman atau Arabika kepada gubernur Belanda yang memerintah Indonesia agar dapat dikembangkan di india, khususnya di Batavia. Produksi awal Nescafe di mulai pada tahun 1930, Ketika pemerintah Brazil pertama kali mendekati Nestle Company. Terdapat salah satu foto ilustrasi dengan produk Nescafe yang menggambarkan semangat remaja saat beraktivitas. Tujuan penulis untuk memvisualisasikan semangat beraktivitas saat mengkonsumsi Nescafe caramel macchiato. Metode berkarya yang digunakan dalam pengumpulan data yaitu data sekunder yang dilakukan melalui data pustaka yang terdapat dari karya tulis ilmiah berupa jurnal yang sudah ada sebelumnya dan referensi foto dari Creative Photography. Penulis akan membuat karya fotografi ilustrasi sebagai media melalui Nescafe caramel macchiato dengan konsep visualisasi gaya hidup remaja yang secara detail memperlihatkan ekspresi dan pose yang sesuai dengan konsep semangat bersama Nescafe yang menggunakan teknik pencahayaan high key yang memiliki cahaya terang dan memberikan kesan warna cerah dengan latar yang berbeda, model dengan pakaian yang berbeda dan properti dengan sesuai konsep. Berdasarkan pengamatan tersebut, memberikan sebuah kesimpulan bahwa dengan menerapkan teknik foto ilustrasi pada Nescafe caramel macchiato dapat memberikan pesan yang ingin disampaikan pada foto.
ANALISIS PENGARUH PRODUK DOMESTIK REGIONAL BRUTO (PDRB) DAN INFLASI TERHADAP KONSUMSI RUMAH TANGGA DI KABUPATEN BANDUNG JAWA BARAT
Authors: Ratna Dewi Dalta , Curry Khirstina
Published: January 2024

Salah satu definisi konsumsi adalah kegiatan yang dilakukan dengan tujuan menghabiskan nilai guna dan juga untuk memenuhi kebutuhan individu atau bersamaan. Tjuan penelitian yaitu untuk menganalisis pengaruh produk domestik regional bruto dan inflasi terhadap konsumsi masyarakat di kabupaten Bandung Jawa Barat. Data yang digunakan bersumber dari Badan Pusat Statistik (BPS) dan Open Data Jabar. Metode pengumpulan data yang di gunakan adalah metode kuantitatif , dan menggunakan Teknik analisis regresi linier berganda. Data yang dimiliki adalah data sekunder dengan jumlah tahun yaitu lima tahun mulai dari tahun 2017-2021. Hasil penelitian menunjukan  bahwa Produk domestik regional bruto (X1) secara parsial berpengaruh negatif dan tidak signifikan tehadap konsumsi rumah tangga di Kabupaten Bandung Jawa Barat, dimana naik turunnya pendapatan  pemerintah tidak ada pengaruhnya terhadap konsumsi rumah tangga. Inflasi (X3) secara parsial berpengaruh positif dan signifikan terhadap konsumsi rumah tangga di Kabupaten bandung Jawa Barat, dimana semakin tinggi inflasi berdampak pada konsumsi rumah tangga.
MENGHAFAL AL-QURAN: TINJAUAN FUNGSI KOGNITIF
Authors: Adriani Donna , Amani Patwa , Putri Mustika Anggiane , Imran Yudhisman , Fauzi Ahmad
Published: January 2024

Cognitive function is a mental process consisting of knowledge, information processing, and reasoning. Cognitive functions include the domains of perception, memory, learning, attention, decision-making, and language skills. Assessment of cognitive functions consists of attention and concentration, executive function, memory, language, visuoconstruction skills, conceptual thinking, calculation, and orientation. Cognitive disorder is a maladaptive response characterized by impaired memory, disorientation, incoherence and difficulty thinking logically. Memorization involves various complex processes called basic cognitive processes which include encoding, storing, and recalling memories, because these processes occur in many memory systems that function differently but are interconnected with one another. Al-Quran is the holy book of Muslims that comes from Allah SWT and was revealed through the Prophet Muhammad SAW. Memorizing the Al-Quran can stimulate the neurotrophin factor. In adulthood, there is a decrease in cognitive function of 6.7%. Cognitive function can be assessed from the serum levels of Brain Derived Neurotrophic Factor (BDNF) and serum Nerve Growth Factor (NGF). Brain Derived Neurotrophic Factor is a protein that increases the survival of neurons and synapses that play a role in learning and memory processes. Nerve Growth Factor is a protein that plays a role in the growth, development and maintenance of nerve cells. The purpose of this study is to explain physiologically the effect of memorizing the Al-Quran on cognitive function in terms of serum BDNF and NGF levels. Based on the results of several studies, it was found that memorizing the Al-Quran continuously can improve cognitive function.
KAJIAN DAYA TAMPUNG BEBAN PENCEMAR SUNGAI CIUJUNG KABUPATEN SERANG PROVINSI BANTEN
Authors: Pramuswara Alfian Pradigda , Fachrul Melati Ferianita , Astono Widyo
Published: January 2024

This Final research was conducted in Ciujung River where this research was conducted in Serang Regency with its head in Nagara Village, Serang Regency, and downstream in Tirtayasa Village, Serang Regency. The research was conducted for 3 months from October – December 2022 starting from 09.00 – 12.00 and continuing from 12.00 – 13.45. The purpose of the study is to identify and determine the sources of pollution that have the potential to pollute the Ciujung River, analyze water quality, water quality status, and pollutant levels in the Ciujung River, and analyze the carrying capacity of polluter loads in the Ciujung River. And analyze the burden of pollutants in the Ciujung River. The length of the Ciujung River studied is 31.3 km. The parameters used for this study are pH, Temperature, DO, BOD, COD, Nitrate, Phosphate, and Total Coliform. The method used in identifying the source of pollution contained in the Ciujung River is carried out by conducting field observations and taking samples of Ciujung River water. Sampling in the Ciujung River was carried out by the grab sampling method. which is done at 6 sampling points. Analysis of river water quality was carried out at the Trisakti University Laboratory. The results of the analysis are then compared with the quality standards of PP No. 22 of 2021 in Attachment VI. Water Quality Status is calculated by the Polluter Index method. Nonpoint sources of pollution are dominated by residential areas, stalls, garbage, shops, mosques/prayer rooms, schools, and markets. Point sources of pollution are obtained from industrial areas. Measurement of river characteristics is carried out in October, November, and December by measuring distance, width, depth, cross-sectional area of the river, river speed, and river discharge. The results of the analysis of water quality in the river stated that for phosphate parameters almost all exceeded quality standards due to domestic waste from the environment, the runoff of agricultural fertilizers, livestock waste, and very high industrial activities. The BOD parameters at point 2 and point 5 exceed the quality standards due to the content of organic waste. The load capacity of BOD pollutants is 3.64 kg/day – 20.20 kg/day, COD is 42.63 kg/day – 144.22 kg/day, Nitrate is 1.67 kg/day – 3.47 kg/day, Phosphate 0.79 kg/day – 3.11 kg/day, Total Coliform is 8694.19 kg/day – 33042.56 kg/day. BOD Pollution Load of 314.26 kg/day- 1744.99 kg/day COD of 2365.46 kg/day - 12460.37 kg/day Nitrate of 144.55 kg/day- 423.16 kg/day Phosphate of Total Coliform of 454133.37 kg/day – 2854876.86 kg/day.
PENERAPAN KARATERISTIK BANGUNAN DI KAWASAN SUMBU FILOSOFI YOGYAKARTA TERHADAP PERANCANGAN DESAIN JOGJA PLANNING GALLERY
Authors: Habibah Annisa Nur , Ischak Mohammad , Iskandar Julindiani
Published: January 2024

Sumbu filosofi merupakan garis lurus yang ditarik dari Panggung Krapyak, Keraton Yogyakarta, dan Tugu Pal. Sumbu filosofi juga merupakan simbol dari keselarasan dan keseimbangan hubungan manusia dengan Tuhannya, manusia dengan manusia, dan manusia dengan alam. Bangunan yang berada di Kawasan sumbu filosofi harus mewujudkan citra karakter kawasan Sumbu Filosofi yang merupakan bagian dari Sumbu Imajiner, yang berupa garis lurus yang sudah diatur dalam peraturan. Permasalahan yang ditimbulkan dari penelitian ini adalah apakah bangunan yang terdapat pada kawasan sumbu filosofi ini sudah dapat merespon terhadap peraturan-peraturan yang berlaku pada kawasan sumbu filososfi. Tujuan dari penelitian ini yaitu untuk mengidentifikasi karateristik bangunan pada kawasan tersebut yang sesuai dengan peraturan setempat. Metode yang digunakan pada penelitian ini adalah metode kualitatif yang dilakukan dengan studi literatur dan studi preseden. Dari hasil penelitian ini menggambarkan tentang peraturan bangunan dan seperti apa karateristik bangunan-bangunan yang terdapat pada kawasan Sumbu Filosofi yang dapat dijadikan sebagai acuan dalam perancangan desain Jogja Planning Gallery. Kesimpulan yang diperoleh dari penelitian ini yaitu beberapa bangunan pada kawasan sumbu Filosofi menggunakan gaya arsitektur indis dan cina, oleh karena itu gaya arsitektur tersebut dapat diterapkan pada desain Jogja Planning Gallery.
HUBUNGAN KADAR TROMBOSIT DAN KADAR LIMFOSIT TERHADAP DERAJAT GEJALA PADA PASIEN COVID-19
Authors: Ekklesia Josephine Maria , Khairani Rita
Published: January 2024

Corona virus disease 2019 (COVID-19) merupakan infeksi sistemik yang mengganggu sistem imun dan kondisi hemostasis tubuh. Manifestasi klinis yang ditimbulkan bervariasi. Pemeriksaan hematologi menjadi pemeriksaan diagnostik yang cukup baik dalam menilai perkembangan penyakit. Selain tersedia luas, pemeriksaan ini terjangkau, efisien waktu dengan hasil yang akurat. Beberapa penelitian menemukan kadar trombosit dan limfosit yang abnormal berperan sebagai salah satu faktor yang mempengaruhi tingkat mortalitas pada derajat infeksi SARS-CoV-2. Untuk dapat membuktikan peran parameter trombosit dan limfosit, maka perlu dilakukan penelitian untuk menilai adanya hubungan antara derajat gejala yang dialami pasien COVID-19.

Metode yang digunakan pada penelitian ini adalah studi observasional dengan desain potong lintang. Responden yang terlibat merupakan pasien COVID-19 di RSUD Budhi Asih Jakarta yang memenuhi kriteria inklusi dan eksklusi yang telah ditetapkan. Pengambilan data menggunakan data sekunder rekam medis yang digunakan untuk menentukan derajat gejala pasien, dan hasil pemeriksaan laboratorium darah terkait. Analisis data dilakukan dengan SPSS for Windows menggunakan uji Fisher Exact dan uji Chi-square dengan tingkat kemaknaan sebesar 0,05.

Pada hasil penelitian ini didapatkan hubungan bermakna antara kadar trombosit (p = 0,023) dan kadar limfosit (p < 0,001) dengan derajat gejala COVID-19.

Penelitian ini menyimpulkan, terdapat hubungan yang bermakna antara kadar trombosit dan kadar limfosit terhadap derajat gejala pada pasien COVID-19.
INDIKATOR SENSE OF PLACE KAMPUNG KOTA DAN RUSUNAWA
Authors: Sari Novita , Wiranegara Hanny W. , Supriatna Yayat
Published: January 2024

Konsep sense of place pada perumahan digunakan untuk menggambarkan ikatan antara penghuni dengan tempat tinggalnya. Dalam perencanaan perumahan, sense of place menjadi salah satu ukuran penting didalam membangun komunitas. Perumahan tidak sekedar sebagai tempat bernaung tetapi juga sebagai tempat yang dapat memunculkan ikatan. Penelitian ini bertujuan untuk mengidentifikasi indikator sense of place pada kampung kota dan rusunawa. Kampung kota mewakili perumahan yang tumbuh alamiah, sedangkan rusunawa mewakili perumahan terencana. Sense of place memiliki tiga dimensi, yaitu place identity, place attachment dan place dependence. Setiap dimensi berturut-turut menggambarkan identitas penghuni, kecintaan penghuni atas tempat tinggalnya, dan ketergantungan penghuni pada tempat tinggalnya. Sebagai kasus kampung kota dipilih Kampung Kali Apuran, sedangkan rusunawa diambil Rusunawa Daan Mogot. Teknik pengumpulan data digunakan metode survei angket. Responden sebanyak 61 keluarga penghuni kampung kota dan 61 keluarga penghuni rusunawa. Teknik analisis menggunakan second order confirmatory factor analysis dengan bantuan SmartPLS. Hasil analisis menunjukkan bahwa identitas tempat, cinta tempat, dan ketergantungan pada tempat (orde pertama) terbukti dapat mengukur sense of place penghuni kampung kota maupun rusunawa. Perbedaan terletak pada orde kedua, yakni pada tingkat indikator dimensi sense of place. Indikator yang signifikan dan berlaku baik di kampung kota maupun rusunawa terletak pada dimensi place dependence, yakni ketersediaan berbagai fasilitas dan perumahan dapat memenuhi seluruh kegiatan penghuni. Ke dua indikator ini perlu menjadi perhatian pada setiap tipe perumahan agar terbangun komunitas.
INDUKSI OKSITOSIN SELAMA PERSALINAN BERHUBUNGAN DENGAN KEJADIAN ASFIKSIA PADA NEONATUS CUKUP BULAN
Authors: Farhatussalihah Nita , Kurniasari Kurniasari
Published: January 2024

Di Indonesia, hampir separuh dari seluruh kematian bayi terjadi pada masa neonatal. Penyebab utama kematian bayi adalah asfiksia. Terdapat faktor risiko yang dapat menyebabkan asfiksia pada neonatus, diantaranya adalah pemberian oksitosin untuk induksi persalinan. Penelitian ini mengambil data dari rekam medis dengan sampel berjumlah 292 neonatus lahir cukup bulan per vaginam di Rumah Sakit Umum salah satu Kabupaten di Jawa Barat. Subjek dengan hipertensi pada kehamilan, berat badan lahir rendah, lahir per vaginam dengan alat bantu, ketuban pecah dini, induksi persalinan lainnya tidak diikutsertakan dalam penelitian. Data diuji menggunakan uji chi-square dengan tingkat kemaknaan 0,05. Tujuan penelitian ini adalah untuk menganalisa hubungan antara induksi oksitosin dan usia ibu dengan kejadian asfiksia pada neonatus. Penelitian ini menemukan prevalensi kejadian asfiksia pada neonatus dengan pemberian induksi oksitosin sebesar 63,3% dan adanya hubungan antara pemberian oksitosin dengan kejadian asfiksia pada neonatus (p=0,003), sedangkan usia ibu tidak berhubungan dengan kejadian asfiksia (p=0,128). Pemberian oksitosin untuk mempercepat proses persalinan sebaiknya hanya digunakan untuk kasus tertentu untuk menghindari kemungkinan terjadinya asfiksia neonatorum.
PENGUATAN KEAMANAN SIBER PADA SEKTOR JASA KEUANGAN INDONESIA
Authors: Luthfah Diny
Published: January 2024

Keamanan siber pada sektor jasa keuangan menjadi prioritas utama karena adanya proses perubahan ke sistem digital berdasarkan Cetak Biru Transformasi Digital Perbankan yang dikeluarkan oleh Otoritas Jasa Keuangan. Hal ini seiring dengan perubahan teknologi dan ancaman yang semakin kompleks sehingga keamanan jaringan menjadi indikator utama dalam sistem digital. Sehingga menjaga keamanan dari sistem informasi teknologi pada sektor jasa keuangan memerlukan tindakan pengamanan lanjutan. Penelitian akan menjelaskan mengenai kebijakan pengaturan hukum pada sistem keamanan siber pada sektor keuangan di Indonesia. Metode penelitian yang digunakan adalah penelitian normatif dengan melakukan analisa data peraturan dan juga dari sumber lain seperti jurnal dan buku. Sektor jasa keuangan merupakan kumpulan perusahaan dan institusi serta lembaga pendukung yang bergerak di bidang keuangan dengan menyediakan produk pada jasa keuangan untuk masyarakat. Sektor yang termasuk dalam jasa keuangan meliputi perbankan, non bank dan pasar modal. Penguatan keamanan siber pada sektor jasa keuangan non bank dan pasar modal perlu segera diadakan pengaturan hukum karena ancaman dan insiden siber melalui teknologi informasi tidak hanya kepada bank namun juga ditujukan kepada sektor jasa keuangan selain bank. Untuk itu dalam penelitian ini kami memberikan saran untuk segera dibentuk kebijakan dan peraturan hukum pada sistem keamanan siber pada sektor jasa keuangan selain bank.
ANALISIS PENCEMARAN AIR TANAH BERDASARKAN PENATAAN JARAK SUMUR GALI DENGAN TANGKI SEPTIK DI KELURAHAN SUKAMAJU, DEPOK, JAWA BARAT
Authors: Syavitri Dewi , Khadafi Khadafi , Yuslim Silia , Amri Adimas
Published: January 2024

Penelitian ini bertujuan untuk mengetahui apakah terdapat keterkaitan antara kualitas air tanah dengan penataan jarak sumur gali air bersih terhadap tangki septik. Penelitian dilakukan di Kelurahan Sukamaju, Depok, Jawa Barat, dengan mengamati 6 lokasi pengamatan untuk mengetahui kedalaman air tanah, jarak  dan posisi sumur gali terhadap tangki septik. Selain itu conto air juga diambil untuk mengetahui apakah terdapat kandungan bakteri Escherchia coli dalam air sumur gali tersebut. Berdasarkan hasil pengukuran terhadap tinggi air tanah dan bantuan software Arc GIS, diketahui arah aliran air tanah bergerak dari Selatan ke Utara dan dari hasil pengamatan diketahui 2  lokasi pengamatan memiliki jarak antara tangki septik dengan sumur gali dibawah ketentuan SNI. Adapun berdasarkan hasil analisis laboratorium mikrobiologi, diketahui 1 titik lokasi pengamatan mengalami kontaminasi bakteri Escherchia coli yang diperkirakan penyebabnya adalah jarak antara sumur gali dengan tangki septik dibawah persyaratan, meskipun arah aliran berlawanan dengan posisi tangki septik. Berdasarkan data tersebut disimpulkan untuk Kelurahan Sukamaju, Depok, secara umum memiliki kualitas air tanah dan penataan jarak sumur gali terhadap tangki septik yang baik.
Responsabilidade em Kant e em Lévinas: entre os conceitos e os fundamentos [Responsability according to Kant and to Lévinas: between the concepts and the foundations]
Authors: De Meneses Ramiro Délio Borges , Reis Ana M. Machado Gonçalves
Published: January 2024

Segundo Kant, a responsabilidade é o desempenho formal da liberdade. Emprimeiro lugar, está a liberdade e só depois virá a responsabilidade, segundo aCrítica da Razão Prática, segundo o imperativo categórico da razão prática. Porém,para Lévinas, no âmbito da fenomenologia religiosa, primeiro encontramose vivemos a responsabilidade, para só depois surgir a liberdade. A responsabilidadeserá um dar prioridade ao Outro. Será um sofrer com Ele e por Ele. Todavia,em Kant, pelo conceito de Freiheit , existe uma ética deontológica, enquantoque, na perspectiva de Lévinas, surge, pela sua fenomenologia bíblica, umaética da responsabilidade, como filosofia primeira, cuja ética será a metafísica.Palavras-chave: Kant; Lévinas; responsabilidade; liberdade; moralidade.
Análise e síntese lógica em Tomás de Aquino [Logical analysis and synthesis by Thomas Aquinas]
Authors: Salles Sergio de Souza
Published: January 2024

Dentre os empregos dos termos análise (“resolutio”) e síntese (“compositio”),um dos mais promissores consiste em sua especificação como modos ou tiposde raciocínio. Compreender a natureza e a finalidade de um tipo específico de“resolutio” e “compositio” em Tomás de Aquino é o principal objetivo do presenteestudo, que se ocupa tão somente dos conceitos genéricos e específicos,das proposições e de suas relações nos raciocínios, objetos característicos darazão humana e o sujeito específico da lógica.
Estética na Filosofia Medieval [Aesthetics in medieval Philosophy]
Authors: Costa Marcos Roberto Nunes
Published: January 2024

Fazendo uma junção entre a concepção cosmológico-filosófico-racional do Beloda Filosofia Antiga e os princípios judaico-cristãos, notadamente à concepçãoteleológica de que o homem é um ser para Deus, o qual se alcança pelainterioridade humana, a Filosofia Medieval, combatendo o “sensualismo” e“imanitismo” dos Antigos, acabaria por superar a própria Filosofia Antiga, construindouma nova Estética de caráter cosmológico-filosófico-religiosa, voltadapara o inteligível enquanto ser transcendental – Deus. Na nova Estética Medieval,a Arte é instrumento de contemplação (imitação da natureza) e tem comofinalidade catequética conduzir o homem ao seu interior, lugar do encontro consigomesmo e com Deus.
Qual liberdade? Hegel e os reformadores prussianos [Which liberty? Hegel and the Prussian reformers]
Authors: Rosenfield Denis Lerrer
Published: January 2024

O presente texto tem como núcleo principal de suas indagações a exploração deum tema não enfrentado na história da filosofia: a relação entre a escola dosreformadores e a filosofia de Hegel. Para a compreensão desse núcleo de relações,far-se-á uma reconstrução da história desse período à luz dos principaisacontecimentos filosóficos, mostrando como Hegel e os reformadores tinhamum pressuposto comum: a reflexão sobre a ‘ideia’ da Alemanha e as causas deseu estado de coisas. Essa pergunta pela Alemanha, num sentido filosófico, é apergunta que se faz capaz de responder tanto à relação entre Hegel e osreformadores, como a relação entre o antigo e o novo, o fim da Idade Média e aModernidade, entre a history e a Geschichte, entre Hegel e nós, à luz da primeirapergunta entre Hegel e os reformadores prussianos.
A ciência da lógica de Hegel como chave para uma leitura filosófica da história da filosofia
Authors: Peralta Carlo Paim
Published: January 2024

In the Science of Logic Hegel presents his speculative logic, the system of categories through which thought thinks itself. By developing the categories one from the other, thought moves immanently, without losing its unity. The justification of philosophy can only be reached within its own interior, and by reaching the Absolute Idea, the final category, with which thought truly expresses itself, it would reach the circularity capable of providing this self-justification. But such circularity does not seem to be enough to deal with the skepticism aroused by the perplexity faced with the diversity of philosophical systems. Hegel then proposed a philosophy of the history of philosophy according to which the truth reached by speculative logic would manifest itself in history, converting it into an argument in favor of, and not against, the truth of his philosophy.
Infecção da corrente sanguínea relacionada ao cateter de hemodiálise
Authors: Brito Francisca Iris Araújo de , Nascimento Maria Eduarda Silva do , Oliveira Daniele Soares de , Ribeiro Ana Gedália Dias , Lino Cristiane Ribeiro de Melo , Flor Joana Darc de Araújo , Souza Mariana da Silva , Pennafort Viviane Peixoto dos Santos , Nunes Vilani Medeiros de Araújo , Mendonça Ana Elza Oliveira de
Published: January 2024

Objetivo: Conhecer a produção científica acerca das infecções da corrente sanguínea associadas ao cateter venoso central em indivíduos em tratamento de hemodiálise. Métodos: Trata-se de uma revisão integrativa, realizada em março de 2023, desenvolvida a partir de estudos disponíveis no formato digital, publicados em periódicos indexados às fontes de dados nacionais e internacionais na Literatura Latino-Americana e do Caribe em Ciências da Saúde, National Library of Medicine, SciVerse Scopus, Scientific Electronic Library Online e Wiley Online Library. Resultados: Identificou-se 13.299 artigos, após a implementação dos critérios de inclusão foram selecionados oito estudos como amostra final. A maioria das publicações eram internacionais e se concentraram no ano de 2022, evidenciou-se números preocupantes acerca de infecções relacionadas ao cateter para hemodiálise por microrganismos gram-positivos, estando associadas às internações hospitalares e mortalidade populacional. Considerações finais: O estadiamento infeccioso encontra-se associado à presença de fatores de risco que permeiam desde aspectos individuais, aspectos relacionados aos microrganismos e à própria terapia hemodialítica. Os cuidados identificados na literatura irão subsidiar a elaboração de critérios de qualidade para o monitoramento dos pacientes em uso de cateter, com vistas à redução de infecções e aprimoramento de processos para o controle destas.
Diabetes tipo 1 e suas principais complicações
Authors: Müller Vanessa Martini , Costa Joice Barros de Oliveira , Vasconcelos Janaína Soares Cardoso de , Santos Geovana Carvalho dos , Soares Deyze Alencar
Published: January 2024

Objetivo: Compreender as principais complicações relacionadas ao Diabetes tipo 1 nos últimos 5 anos. Métodos: Esse artigo trata-se de uma revisão integrativa, observada nas bases de dados LILACS, PubMed e SciELO, tendo como Descritores em Ciências da Saúde (DeCS): diabetes mellitus tipo 1 e complicações, contemplando os estudos que compõem a amostra a partir dos critérios de inclusão e exclusão preestabelecidos. Resultados: Neste estudo, foram encontrados 22 artigos, onde a cetoacidose diabética foi esclarecida como uma complicação emergencial, levando em consideração a fisiopatologia da doença e que existem outras complicações importantes a serem estudadas. Considerações finais: Considera-se que o Diabetes Mellitus é um tema de extrema importância e uma doença que deve ser tratada desde seu diagnóstico. Apresentando vários fatores para serem considerados, desde a fisiopatologia às complicações, sejam elas, crônicas ou agudas. Portanto, é preciso de mais estudos referentes a relação da hiperglicemia, cetoacidose diabética e da hipoglicemia com alterações do déficit neurológico, emocionais e psicológicas em crianças e adolescentes, além de, esclarecer de maneira mais detalhada a respeito da fisiopatologia da doença.
Efeitos da hiperprolactinemia no sistema digestório e melatonina como possível forma de tratamento
Authors: Silva João Vitor da , Tenorio Bruno Mendes , Maia Carina Scanoni , Silva José Anderson da , Santos Aline Maria Rodrigues dos , Silva Alison José da , Silva Isaque Bertoldo Santos da , Silva Ewerton Fylipe de Araújo , Tenorio Fernanda das Chagas Angelo Mendes
Published: January 2024

Objetivo: Descrever os efeitos da hiperprolactinemia no sistema digestório e as ações terapêuticas do hormônio melatonina no organismo. Revisão bibliográfica: A hiperprolactinemia é uma condição decorrente do aumento dos níveis séricos de prolactina, um hormônio sintetizado e secretado principalmente pelos lactotrofos da glândula adeno-hipófise. Na litetarura, já são bem descritos os efeitos da hiperprolactinemia nos sistemas genitais. No entanto, são escassos trabalhos que reportem os efeitos desta condição sobre os demais sistemas do corpo humano. A melatonina é um hormônio versátil que apresenta diversos efeitos protetores no organismo, sendo os mais elucidados relacionados ao seu potencial antioxidante, anti-inflamatório e antioncostático. Considerações finais: Dessa forma, espera-se, a partir da presente revisão de literatura, que sejam realizados novos estudos voltados para a investigação dos prováveis efeitos negativos da hiperprolactinemia sobre os múltiplos sistemas do organismo, visto que algumas temáticas referentes à essa condição ainda não são completamente compreendidas e contam com estudos relativamente antigos. Ademais, espera-se que sejam realizadas pesquisas para verificar a possível atividade protetora do hormônio melatonina frente à condição de hiperprolactinemia no sistema digestório e demais sistemas do organismo. Pesquisas com graus de evidências fortes e atuais são primordiais para melhorar a expectativa e qualidade de vida dos indivíduos.
Orthodontic management of midline diastema caused by mesiodens: A case series
Authors: Roy Rudrani , Khan Suleman , Jabeen Seema , Navit Saumya
Published: January 2024

Supernumerary teeth are teeth in excess of the normal number, found in both primary and permanent dentition. Mesiodens are the most common form of supernumerary teeth, usually found in the maxillary anterior region, in between the permanent central incisors. It may lead to complications such as malocclusion, unesthetic appearance, food lodgment, and cyst formation. Early diagnosis and immediate intervention are advised to avoid orthodontic and pathological complications. The case series here discusses three different cases for presence of supernumerary teeth leading to development of midline diastema. Extraction of the supernumerary teeth followed by fixed orthodontic treatment was performed to correct the malocclusion and improve the facial esthetics.
Blood and Bleeding Management in Developing Economies: Perceptions, Preparedness, and the Evolving Practices
Authors: Mishra Anurag Kumar , Agarwal Atul Kumar , Gandhi Ajay
Published: January 2024

Objectives:

The growing concerns around the judicious use of blood components have paved the way for the dissemination of awareness around the best practices related to the use of this precious resource. With the World Health Organization issuing a policy brief on the urgent implementation of Patient Blood Management (PBM), there has been an accelerated impetus within the healthcare ecosystem to imbibe and implement the principles and practices of PBM. This research work aims to understand the current level of understanding, adequacy, and appropriateness of practices and readiness toward the universal and standardized implementation of PBM.

Approach:

This article summarizes the findings of an online survey. The survey consisted of a Google Form questionnaire with responses in multiple-choice, open and closed ends, as well as short notes. The survey responses were analyzed and summed up graphically. The survey established that there is still a huge gap in the “multispecialty approach” to setting up of the safe tolerance limits to anemia, optimal cutoffs, and thresholds for transfusion and shifting focus from “blood product” safety to “patient” safety.

Conclusion:

A lot of guidance- and evidence-based recommendations on transfusion practices are available in developed economies; the developing world still continues to weigh the advantages against the availability of and access to resources needed for implementation. Within these economies, and among different strata of healthcare infrastructure, there is still a significant difference in the perceptions and practices around blood transfusion and bleeding management.
Technical Details of a Novel Surgical Procedure of Anomalous Left Coronary Artery from the Pulmonary Trunk in a Child Using Autogenous Aortic and Pulmonary Arterial Flaps (UKC’s Modification): A Video Presentation
Authors: Chowdhury Ujjwal K. , George Niwin , Goja Shikha
Published: January 2024

A 18-months-old male child diagnosed with anomalous origin of left coronary artery from the left posterior pulmonary sinus underwent the modification of the “trapdoor” technique, wherein the anomalous left coronary artery was detached from the pulmonary arterial sinus, and combined aortic and pulmonary arterial flaps were used to augment its length. The postoperative recovery was uneventful.
Single-Center, but Multipotent Lewis acids: Illuminating the Multiple Lewis Acidity of Triaryl-Boranes via Atropisomeric Dative Adducts
Authors: Benjámin Kovács , Földes Tamás , Szabó Márk , Dorkó Éva , Kótai Bianka , Laczkó Gergely , Holczbauer Tamás , Domján Attila , Pápai Imre , Soós Tibor
Published: January 2024

We report the illumination of the exotic and peculiar molecular phenomenon of single-centered, but multiple Lewis acidity for triaryl boranes with fine-tuned steric effects and appropriate symmetry design. The existence of this unique molecular property was indirectly confirmed by the formation of B(sp3)–N(sp3) atropisomeric piperidine–borane adducts using state-of-the-art NMR techniques in combination with computational methods. Additional 19F EXSY experiments also revealed that these sterically strained piperidine–borane adducts display conformational interconversions, which take place via dis-sociative rather than rotameric mechanism.
Visible Light-Induced EDA-Mediated C-3 Coupling of Quinoxalin-2(1H)-ones with Unactivated Aryl Iodides
Authors: Sharma Anuj , Singh Nihal , Sharma Anoop , Singh Jitender
Published: January 2024

Visible light-induced C-3 arylation of quinoxalin-2(1H)-ones with abundantly available aryl iodides with good yields via an EDA-complex formation has been accomplished. Both aryl/heteroaryl iodides and quinoxalin-2(1H)-ones possessing electron-donating as well as electron-withdrawing groups were coupled well to access the desired products in good yields. The radical scavenging, EPR, UV-visible experiments, and quantum yield revealed that the reaction went through a radical pathway via a SET process. Furthermore, the protocol could also be applied for late-stage functionalization, illustrated the practicability of the present protocol.
Exploring the Light-Emitting Agents in Renilla Luciferases by an Effective QM/MM Approach
Authors: Nandi Ashim , Zhang Aoxuan , Chu Zhen Tao , Xie Wen Jun , Xu Zhongxin , Dong Suwei , Warshel Arieh
Published: January 2024

Bioluminescence is a remarkable natural process in which living organisms produce light via specific biochemical reactions. Among these organisms, Renilla luciferase, derived from the sea pansy Renilla reniformis, is notable for its blue light emission, making it an ideal candidate for bioluminescent tagging. Our focus lies at RLuc8, a variant with eight amino acid substitutions, recent research has shown that its emitter, coelenteramide, can exist in different protonation states, significantly influenced by proximal proton acceptor residues at the active site. Herein employing the Quantum Mechanical Consistent Force Field (QCFF/PI) method and the semi-macroscopic Protein Dipole-Langevin Dipole method with Linear Response Approximation (PDLD/S-LRA), we show that the phenolate state of coelenteramide in RLuc8 is the predominant light-emitting species, corroborating experimental results. Our calculations also demonstrate that proton transfer from neutral coelenteramide to Asp162 is integral to the bioluminescence mechanism. Furthermore, our calculations accurately reproduce the observed emission maximum for the amide anion in RLuc8-D120A, which is responsible for chemiluminescence. In the case of RLuc8-D162A, we observed that the pyrazine anion, existing in the presence of a Na+ counterion, has an emission maximum consistent with experimental data, suggesting its primary role as potential emitter. This study not only showcases an effective way for investigating the bimolecular states of chromophores in light emission but also introduces an efficient approach that integrates the proton transfer process into the calculations of the emission spectrum, proving vital for further research of proton transfer and light emission in photoproteins.
How Financial Literacy, Financial Attitudes and Personality Affect MSMe Management Behavior? Case in Bengkulu
Authors: Aziz Dwi Abdul , Zoraya Intan
Published: January 2024

MSMEs often overlook the presence of financial management, particularly the implementation of appropriate financial management and accounting standards. As a result, financial management becomes a problem for them. Micro business actors often do not know much about accounting and their education also influences their knowledge. This research aims to determine the effect of financial literacy, financial attitudes and personality on financial management behavior among MSMEs in Bengkulu City. The population of this research is MSME entrepreneurs in Bengkulu, with taking 101 samples. To determine the samples, this study uses a random sampling technique. Finally, the research results show that financial literacy effects financial management behavior, financial attitudes and personality with 0.428. In addition, the R Square value is 0.851, meaning that Financial Literacy, Financial Attitude and Personality impact Financial Management Behavior with 85.1%. Independent variables outside the model influence the remaining dependent with 14.9%. Furthermore, MSME actors needs to improve their skills, knowledge and attitude to manage their finances sensibly. A proper financial behavior could rise with possessing an access to all the financial information that may require in order to make financial decisions.
Two-component Supramolecular Adduct based on Hydroxyl Substituted Triptycene with 4,4’-bipyridine: Crystal Structure Analysis
Authors: Dua A. , Titi H.M. , Sharma H.K. , Roy S.
Published: January 2024

A new cocrystal solvate possessing 2,7,14-trihydroxytriptycene (THT) and 4,4′-bipyridine (bpy) was grown from a MeOH solution by solvent evaporation to form THT·0.5bpy·MeOH·H2O (1).The crystal structure of 1 was determined by single-crystal X-ray diffraction in the monoclinic space group C2/c. In the new cocrystal solvate (1), the asymmetric unit consists of one unit of THT, a half unit of disordered bpy, one unit of a water molecule and one MeOH molecule. A 2D supramolecular architecture is observed in (1) linking THT, bpy and solvent water molecules via classical O-H···N and O-H···O hydrogen bonds. The MeOH and water molecules entrapped in (1) form stabilizing hydrogen bondswith the surrounding “trimeric cocrystals.” Furthermore, we investigated whether these hydrogen bonds stabilize the crystal packing. The calculations were carried out using Hydrogen Bond Statistics and Full Interaction Maps packages, and the results exhibit common bonding behaviour in terms of bond distances and strength.
Tuning the dimensionality of H bonded networks using different chalcogen atoms in [Re6Q8(CN)6]4– (Q = S, Se) clusters
Authors: Ledneva A.Yu. , Naumov N.G. , Kyritsakas N. , Ferlay S.
Published: January 2024

Two novel compounds based on [Re6Q8(CN)6]4– (Q = S, Se) and small H bond donor bis-amidinium dication of 2,2’-methylenediimidazolium (Cat) (Cat)2[Re6S8(CN)6]∙2H2O (1) and (Cat)2[Re6Se8(CN)6]∙2H2O (2) were synthesized and structurally characterized. Depending of the chalcogen atom (S or Se) in the cluster anion, the dimensionality of the obtained (2D and 3D) network and the nature of the H bond pattern change.
Investigation of Treatability of Automotive Industry Wastewaters by Coagulation-Flocculation, Fenton and UV/H2O2
Authors: ALDIĞ Semih Ayberk , SÖNMEZ Gamze
Published: January 2024

In the automotive industry, painting operations have emerged as a major source of environmental concerns. In this study, the treatability of wastewater obtained from the automotive industry painting process was investigated by using coagulation-flocculation, ultraviolet/hydrogen peroxide (UV/H2O2), and Fenton processes. The effects of pH, coagulant, and anionic polymer doses were examined for three different coagulants in the coagulation-flocculation process. Optimal conditions were determined based on chemical oxygen demand (COD) and turbidity removal efficiency. As a result of the study, the optimum conditions for the coagulant identified as ferric chloride, which achieved the highest COD removal of 49.6% and turbidity removal of 74.4%, were determined as pH 8, coagulant dose of 400 mg L-1, and anionic polymer dose of 1 mg L-1. In the second stage of the study, Fenton and UV/H2O2 processes were applied to the effluent of the coagulation-flocculation process to increase the removal efficiency. When the results were evaluated, it was observed that the maximum COD removal efficiency of 63.4% was attained under the conditions of pH 3 and 400 mg L-1 H2O2 concentration applied in the UV/H2O2 process. However, in the Fenton process, a maximum COD removal efficiency of only 51% was achieved. From this study, it can be concluded that the UV/ H2O2 process applied after coagulation-flocculation increases the removal efficiency and can be an alternative and effective treatment process for wastewater from the automotive painting process.
Factores asociados al desarrollo de polineuropatía, miopatía y polineuromiopatía en pacientes adultos críticos
Authors: Herrera Rodríguez Diana Isabel , Delgado Martha , Santaella-Tenorio Julian , Ortega-Lenis Delia , Quintero Orlando
Published: January 2024

Introducción. La polineuropatía, la miopatía y la polineuromiopatía son condiciones debilitantes que afectan a pacientes críticamente enfermos. Sin embargo, poco se conoce acerca de los factores relacionados con estos desenlaces en pacientes hospitalizados en las unidades de cuidado intensivo (UCI) y con hospitalización prolongada en el contexto clínico colombiano.
Objetivo. Evaluar los factores asociados al desarrollo de polineuropatía, miopatía y polineuromiopatía en pacientes críticos con hospitalización prolongada.
Métodos. Estudio analítico, observacional, de casos y controles apareados realizado en 192 pacientes (64 casos y 128 controles) atendidos en una clínica de tercer nivel de atención de Cali, Colombia. Se analizaron diferentes factores de riesgo como falla multiorgánica, sepsis, desnutrición, nutrición parenteral, uso de corticoides, uso de relajantes musculares, entre otros. Se evaluó si los días de estancia en UCI es un modificador del efecto de la relación entre estos factores y los desenlaces.
Resultados. Se encontró que la falla multiorgánica (OR: 6,32, IC95%: 2,15-18,58), la desnutrición (OR: 2,25, IC95%: 1,01-5,0) y el uso de relajantes musculares (OR: 2,68, IC95%: 1,04-6,87) estuvieron asociados con el desarrollo de polineuropatía y miopatía. Así mismo, se observó que la asociación entre la falla multiorgánica y estas condiciones se vio afectada por la duración de la estancia en UCI (p<0,05). En pacientes sin falla multiorgánica, el riesgo aumentó mínimamente con cada día adicional de estancia en UCI (OR: 1,004, IC95%: 0,97-1,04); sin embargo, en pacientes con falla multiorgánica, el riesgo se incrementó en un 5% por cada día adicional de estancia en UCI.
Conclusiones. Los resultados del presente estudio destacan la importancia de factores como la falla multiorgánica, la desnutrición y el uso de relajantes musculares en el desarrollo de la polineuropatía, la miopatía y la polineuromiopatía en pacientes críticos con hospitalización prolongada.
El emprendimiento desde las incubadoras de negocios, una revisión de literatura
Authors: Landeros-García Carlos , Mayela-Terán María Mayela , Caballero-Campbell Aldahir
Published: January 2024

Las incubadoras de negocios son entidades que ofrecen a los emprendedores el soporte para transformar ideas innovadoras en emprendimientos de éxito a través de su programa de incubación y su infraestructura instalada. La importancia de estos nuevos emprendimientos radica en su aportación al desarrollo económico pues generan empleabilidad y flujo económico en la entidad residente. El objetivo de esta investigación es realizar un análisis documental para identificar factores clave en el proceso de incubación que impulsen de manera positiva el éxito del proyecto de negocio. Como resultado de la revisión literaria se identifican 4 factores que se encuentran relacionados positivamente al éxito empresarial.
Diferencias entre el género con respecto al deseo, los motivos y las dificultades para emprender, la actitud emprendedora y la percepción del emprendedor de los estudiantes en México
Authors: García-González María Alejandra , Huerta-Cerda Zita Mithala , Pedroza-Cantú Gloria
Published: January 2024

El emprendimiento es importante para el desarrollo individual y social, porque beneficia a la economía de un país. En México se han generado cambios en las instituciones responsables de afianzar la cultura emprendedora, así como programas de financiamiento para la creación de nuevas empresas. La literatura sobre emprendimiento y género presenta diferencias significativas que favorecen a hombres y descubren mayores dificultades para mujeres en aspectos relacionados con la falta de experiencia en el sector empresarial, menor conocimiento del negocio, falta de recursos para emprender individualmente y mayor dependencia respecto de los ingresos de la empresa. El objetivo de este estudio es identificar las diferencias, entre hombres y mujeres jóvenes en México, en relación con diversas variables relacionadas al emprendimiento en la futura creación de una empresa. Para lograr lo anterior se encuesto a 340 estudiantes de una universidad pública del noreste de México. Los resultados muestran que existen algunas diferencias importantes entre hombres y mujeres jóvenes en cuanto a emprendimiento se refiere.
Pelaksanaan Restitusi Terhadap Anak Korban Kekerasan Seksual
Authors: Dewu Cindy , Rodliyah Rodliyah , Pancaningrum Rina Khairani
Published: January 2024

Anak adalah seseorang yang belum berusia 18 tahun dan termasuk yang berada didalam kandungan. Kondisi anak yang belum bisa mempertahankan dirinya sendiri, membuat anak kerap menjadi korban kekerasan, salah satunya adalah kekerasan seksual yang masih marak menimpa anak. Anak yang menjadi korban kekerasan seksual berhak untuk mendapatkan restitusi. Restitusi adalah pembayaran ganti kerugian yang dibebankan kepada pelaku berdasarkan putusan pengadilan yang berkekuatan hukum tetap atas kerugian materiil dan/atau immateriil yang diderita korban atau ahli warisnya. Pelaksanaan restitusi kepada anak korban tindak pidana telah diatur dalam Peraturan Pemerintah Nomor 43 Tahun 2017 tentang Pelaksanaan Restitusi Bagi Anak Yang Menjadi Korban Tindak Pidana. Walaupun pelaksaan restitusi kepada anak korban telah diatur dalam perundang-undangan, tetapi kenyataannya di tengah masyarakat, pelaksanaan restutisi ini masih jarang dilaksanakan. Sehingga terdapat kesenjangan antara das sollen dan das sein. Penelitian ini bertujuan untuk menganalisa pelaksanaan restitusi terhadap anak korban kekerasan seksual dan untuk menganalisa hambatan dalam pelaksanaan restitusi terhadap anak korban kekerasan seksual. Penelitian yang digunakan adalah penelitian hukum empiris. Pendekatan yang digunakan adalah pendekatan perundang-undangan, pendekatan konseptual, dan pendekatan kasus.. Analisis yang digunakan adalah analisis kualitatif bersifat yuridis deskritif.
Pengembangan Media Pembelajaran Interaktif Edpuzzle dalam Pembelajaran Sejarah
Authors: Purmintasari Yulita Dewi , Lesmana Chandra
Published: January 2024

Learning history is one of the most difficult lessons because of the distance in space and time, so it is necessary to present interactive learning media that make historical values more understandable. The development of Edpuzle interactive video learning media in history learning aims to develop learning media and to determine the effectiveness of the product developed. The research process applies the 4D development research method with the stages of Define, Design, Develop and Deseminate. The research instruments are in the form of expert validation sheets, lift sheets and test questions. The results of the media validation show "very good" worthy of being used as a learning medium with an average score of 4.35. Based on table 2, it shows that the results of the validation of material experts average score of 4.33 in the "very good" category. The results of the one to one evaluation show that the average total score is 3.98 in the "good" category. And the results of the small group evaluation show that the total average score is 4.58 in the "very good" category. the results of the effectiveness test using Mann Whitney U on SPSS, obtained the results of a sig (2-tailed) value of 0.011 <0.05 which means Ho is rejected while Ha is accepted which means the use of interactive media has an effect on learning students become more interested and able to think interactive learning media and not boring.Pembelajaran sejarah merupakan salah satu pembelajaran yang sulit karena jauhnya ruang dan waktu, sehingga perlu menghadirkan media pembelajaran interaktif yang membuat lebih memahami nilai-nilai sejarah. Pengembangan media pembelajaran video interaktif edpuzle pada pembelajaran sejarah bertujuan untuk mengembangkan media pembelajaran dan mengetahui efektivitas produk hasil pengembangan. Penelitian menerapkan metode penelitian pengembangan 4D dengan tahapan Define, Design, Develop dan Deseminate. Instrumen penelitian berupa lembar validasi ahli, lembar angkat dan soal tes. Hasil validasi media menunjukkan “sangat baik” layak digunakan sebagai media pembelajaran dengan skor rata-rata 4,35. Berdasarkan tabel 2 menunjukkan bahwa hasil validasi ahli materi skor rata -rata 4,33 dengan kategori “sangat baik”. Hasil evaluasi   one to one menunjukkan bahwa total skor rata -rata 3,98 dengan kategori “baik”. Dan hasil evaluasi small group menunjukkan bahwa total skor rata -rata 4.58 dengan kategori “sangat baik”. hasil uji efektivitas menggunakan Mann Whitney U pada SPSS, didapatkan hasil nilai sig (2-tailed) sejumlah 0,011 < 0,05 yang berarti Ho ditolak sedangkan Ha diterima yang berarti penggunaan media interaktif berpengaruh dalam pembelajaran. siswa menjadi lebih tertarik dan mampu berfikir dengan media pembelajaran yang interaktif dan tidak membosankan.