bluuebunny/crossref_metadata_2025 huggingface dataset:
Numerical Study of Impact of Grain Profile on the Internal Ballistics of Solid Rocket Motor
Authors: Gupta Ankit , Nair Praveen , Ashish A. S. , Abraham Biju Cherian
Published: December 2023

Solid Rocket Motors (SRM) are engines that use solid propellants for generating thrust in a rocket. SRM plays a crucial role in rocketry. SRM is in widespread use nowadays not only for space purposes but also for the development of missiles and sounding rockets. SRM uses aluminized propellants to improve the efficiency of the rocket motor due to its high heat of combustion and density [1]. On combustion, aluminium gets converted to aluminium oxide (alumina - Al2O3), and the condensed-phase droplets of alumina act on the submerged and nozzle region’s insulation during SRM manoeuvring flight which can cause abnormal ablation of the thermal protection system.

This work presents the numerical simulation of the flow field and particle dynamics in SRMs using the Computational Fluid Dynamics (CFD) tool. Simulations were carried out for a typical SRM by studying the effect of various geometrical parameters on motor performance. Important parameters addressed in this paper include (1) the effect of the ratio of port area (Ap) to throat area (At) and (2) the length of the grain on flow velocity and related particle impingements. Results show that for this study as Ap/At increases, velocity inside the submerged region decreases which in turn points to the fact that the particle impingements in this region decrease. However, this depends on various parameters like particle loading in the propellant, Ap/At, the geometry of the propellant, length of the motor, propellant formulation, geometry of the submerged region and so on. Hence, we cannot generalize this conclusion and one has to perform a detailed study.
A New Approach to Increase the Accuracy of a Numerical Scheme Using Modified Partial Differential Equation : Application to Meshless Methods
Authors: Arora Konark
Published: December 2023

Meshless methods are gaining popularity for numerically solving the governing equations of Fluid Dynamics primarily because they do not require the generation of grid around the given geometry in the computational domain. They just require a point distribution with a proper connectivity, which is extremely simple to generate as compared to the grid around complex geometries. However, obtaining a higher order accurate numerical solution is difficult in case of meshless methods as it requires either a solution of a larger system of linear algebraic equations, or defect correction method coupled with inner iterations. This method becomes too much complicated if still further higher order accuracy is desired. Here an alternate method based on Modified Partial Differential Equations has been used to obtain higher order accurate solution using the meshless methods. The basic idea behind the new approach is to explicitly remove the truncation error from the Modified Partial Differential Equation (formed from the governing equations) and numerically solve the resulting equation with the meshless technique. This technique has been successfully applied for the simulation of subsonic, weak transonic, strong transonic and supersonic flow past NACA0012 aerofoil. A good match of the numerical results with the standard test results of AGARD/GAMM workshop has been.
CFD Study on Water Impact of Spent Stage on Floats Using Overset Grid and Volume of Fluid Approach
Authors: Jangra Jatin , Gohel Vishruti , Salih A. , Aggarwal Vishesh , Priyadarshi Pankaj
Published: December 2023

A transient multiphase CFD analysis using the VOF method coupled with a 6DOF solver is used to model the water impact of a launch vehicle spent stage with floats. Overset Mesh motion technique was used to model the 6DOF based motion of the body. The stability of the spent stage water impact solution was studied by varying implicit mesh update features. The water impact of spent stage with different diameter floats was also studied. The CFD model is validated for the water impact of a wedge which was available in the literature. The CFD predicted results for the wedge case are within the 5% of the measurement in the prediction of maximum penetration depth.
High Order Harmonic Pass Band Suppression in Microstrip Filter
Authors: Dashora Harsh , Roy Ugra Mohan
Published: December 2023

It is very well understood that filters are backbone of communication system as they are employed in each stage of system design and the key parameters which indicates their performance and suitability to desired application are insertion loss, return loss, group delay etc. Apart from them a very important factor namely high order harmonic pass band which becomes very critical when input of the filter consists of multiple harmonic signal within it and creates interference to succeeding stages of the system. In order to achieve clean frequency spectrum in stop band frequency region, there is need of suppressing the high order harmonic spurious pass bands. In this research work additional microstrip patterns are formed at input/output of the filter schematic to achieve the required goal. In this article concept of the novel technique to eliminate or suppress the high order harmonics is detailed and same is implemented on hairpin type of filter topology.
ՀԱՅԱՍՏԱՆԻ ՀԱՆՐԱՊԵՏՈՒԹՅԱՆ ՏԱՐԱԾՔԻ ԼԵՌՆԱՅԻՆ ՀԱՆՔԱԽՈՐՇԵՐԻ ՕԳՏԱԳՈՐԾՈՒՄԸ, ՈՐՊԵՍ ՔԱՂԱՔԱՑԻԱԿԱՆ ՊԱՇՏՊԱՆՈՒԹՅԱՆ ԹԱՔՍՏՈՑՆԵՐ ՊԱՏԵՐԱԶՄԱԿԱՆ ԳՈՐԾՈՂՈՒԹՅՈՒՆՆԵՐԻ ԺԱՄԱՆԱԿ
Authors: Gharibyan Haykandukht , Gasparyan Arayik
Published: December 2023

Sheltering the population in defense structures during military operations is the main means of ensuring the life and activity of the population. From the point of view of protecting the population, the use of mountain mice caverns in the territory of the Republic of Armenia as hiding places during military operations is important.
УПРАВЛЕНИЕ ЛОГИСТИКОЙ, ЭКОНОМИКОЙ, ЭКОЛОГИЕЙ В РЫНОЧНЫХ УСЛОВИЯХ
Authors: Muradyan Elvira , Derdzyan Hasmik , Pikalova Lyudmila , Margaryan Simon , Khachatryan Gohar
Published: December 2023

В статье рассматриваются показатели экономики, экологии, логистики в сфере управления в рыночных условиях.
ՓՐԿԱՐԱՐԱԿԱՆ ԾԱՌԱՅՈՒԹՅԱՆ ՍՊԱՅԻ ՀԱՏԿԱՆԻՇՆԵՐԻ ՁԵՎԱՎՈՐՄԱՆ ՀԱՅԵՑԱԿԱՐԳԱՅԻՆ ՀԱՐՑԵՐ
Authors: Matevosyan Hamlet , Hayrapetyan Armine , Gharibyan Haykandukht , Gspoyan Grisha , Amirkhanyan Hasmik , Nazaryan Lilit
Published: December 2023

The purpose of the article is to present a number of conceptual issues of the formation of characteristics of the officer of the modern rescue service, including the set of knowledge, abilities, skills and norms of behavior that are necessary for the officer as a leader to effectively perform his functions, especially the functions and methods of self-management in team work, knowledge and ability to apply them.
The set of characteristics is discussed from the juridical, ideological and linguistic points of view, trying to outline the way of formation of an officer.
DYNAMICS OF THE NEUROOPHTHALMIC CHARACTERISTICS OF PERINATAL ACUTE STROKE AT THE STAGES OF CHILDREN'S DEVELOPMENT
Authors: Salmanova S.Z. , Mammadbeyli A.K. , Alieva N.Z.
Published: December 2023

The theoretical basis of these studies is based on the dynamics of functional and adaptive relationships of important integrative departments of the Developing Child Brain. It is no coincidence that in recent years studies of the dynamics of cerebral vision disorders in children with pre-and perinatal encephalopathy have expanded in the direction of hemodynamics of Central hemodynamics, general and local cerebral circulation, as well as orbital and intraocular hemodynamics. In the last 5 years, with the help and cooperation of the children's Neurological Hospital, a diagnosis of acute cerebral circulation disorder in the neonatal period of life was detected in 1500 children from 3500 to 3 years of age. In these children, consistent between clinical and laboratory examinations, the dynamics of these indicators of homeostasis-Sommar in blood of catecholamines, their excretion in the urine, differentiated daily, the dynamics of the amount of sugar and cortisol in the blood, as well as electrolytes in plasma and erythrocytes were monitored. While evaluating the results of the additional examination methods, epicrises given to children by children's Neurological Hospital, Republican perinatal Center and research pediatric institute were used. The reaction of Pulse, arterial pressure and respiration to vegetotropic drug preparations and physical load tests was investigated in order to confirm clinical and additional correlations of electrophysiological and Clinico-laboratory results obtained in the children we examined. With known methods, atropine, adrenaline and insulin tests were carried out, the reactivity of Pulse, arterial pressure and respiration to the administration of adrenaline (0.02 mg/kg) and atropine (0.01 mg/kg) into the muscle, as well as the increase in excretion of catecholamines with urine into insulin injection (0.25 unit/kg). Thus, in the neonatal period of life of 1500 children from 3500 to 6 years of age who were involved in the examinations, acute violations of cerebral circulation were diagnosed, as a result of many years of consecutive examinations and treatments, nearly 1000 children with pre – school clinical picture were evaluated for compensation – 15%, remissions – 75%, program walk – 10%. It is proved that the solutions of recovery options depend on the direction of hypothalamic-pituitary relations and homeostatic aberrations.
An unexplored Nexus of Political freedom, Economic Growth, Economic conditions and CO2 emission in Asian Country
Authors: Naveed Jan
Published: December 2023

The promotion of sustainable environmental development is at the forefront of world leaders' policy agendas. The human race is currently confronted with a formidable challenge in the form of a global environmental issue. In each nation, political institutions are responsible for formulating and implementing policy agendas. This study's objective is to examine the relationship between the current state of political institutions, environmental emissions, and development indicators, taking into account the impact of diverse economic conditions such as a free economy, a fluctuating economy, a degraded economy, and an improved economy. Over the course of twenty-four years, from 1998 to 2021, information for this study was collected from ten different ASEAN nations. The panel data methodology is utilized in order to answer the research question. Estimates that account for fixed effects indicate that there is a significant positive correlation between economic growth and CO2 emissions. It is also evident that CO2 emission levels are higher in Asean economies that are more volatile, such as Indonesia and Thailand, while they are lower in economies that have improved, such as Singapore. This is one of the earliest studies conducted on the subject at hand. This study's findings will serve as a guide for implementing environmental policy
IMPACT OF THE GERMANE LOAD ON STUDENTS’ BEHAVIORAL INTENTION ON ONLINE COURSES DURING COVID-19: MEDIATING ROLE OF INSTRUCTIONAL DESIGN AND MODERATING ROLE OF E-LEARNING PERSONALIZATION
Authors: FAN LIN
Published: December 2023

The study is carried out to examine the impact of the germane load on the Students’ Behavioral Intention of students studying in the public universities of China. Meanwhile, the study has also examined the mediating role of instructional design and moderating role of e-learning personalization. The study has used the SEM-PLS is to examine the relationship between and among the variable. The current study has investigated the relationship between germane load and instructional design, future behavioral intentions and instructional design, and future behavioral intentions with the germane load. The survey was conducted among the university students of China who participated in online learning programs during the COVID-19 pandemic. Moreover, the mediation influence of germane load on the relationship of future behavioral intentions and instructional design has been studied. It was found that all the relationships were positively correlated. The mediation influence of instructional design was found between the relationship of future behavioral intentions and instructional design. The study has examined the instructional design as a mediator. The analysis of an instructional design focusing on setting course plans results in improved germane load, which improves the process of learning, and future behavioral intentions among students are increased. It is important to note that usage intention and germane load are benefited through an effective instructional design. Therefore, the association between usage intention and germane load is important to be examined for analyzing a good understanding of the content among students and their plan for continuing e-learning in the future. In literature, studies have worked on instructional design, which results in improved learning and intention to continue e-learning and among students. However, there is a need to explore instructional design that focuses on general course planning to improve behavioral intention in the future based on the previous learning experience. The study is among the pioneers on the issues related to e-learning mechanisms in eastern Malaysia
Does the face expression recognition model under the online entrepreneurial education model important for deep learning technologies and entrepreneurial emotions?
Authors: Majid Ibrahim Mohammed Abdullah Al Zarooni
Published: December 2023

AI's rapid development has already affected the economy and society, and it might revolutionise how goods and services are manufactured and categorized. This affects the country's production, employment rate, and competitiveness. This research aims to determine how emotions (good and negative) impact deep learning technologies and company startup intentions. The research also examined how emotion recognition influences online entrepreneurship education and how deep learning and entrepreneurship are connected In conclusion, the research is one of the pioneering efforts that provides a comprehensive grasp of the deep learning and facial recognition in entrepreneurship. 78 of 650 replies were insufficient, according to the statistics. Some individuals constantly picked 3, while others submitted blank questionnaires. The answer is inadequate. 572 surveys were utilized for study. Positive emotions affect the urge to establish a company, according to the research People who are generally happy may be able to develop their entrepreneurial expertise and be more driven to behave entrepreneurially. Positive and negative emotions have significant impact on the deep learning technology and entrepreneurial intention connection. The findings imply that individuals who often experience pleasant emotions may be better able to improve their entrepreneurial cognition and, as a consequence, their drive to engage in entrepreneurial activity. Facial recognition model in entrepreneurship significantly moderates the relationship between deep learning technology and entrepreneurial intention relationship (=0.262, p 0.001); hence, hypotheses 6, 7, and 8 are validated. This provides support to the hypothesized results, claiming that facial recognition plays a significant role in determining the relationship between the deep learning technology and entrepreneurial intention relationship. The results would be significant for university students, academicians and policymakers as they seek to link practices and outcomes. The study is among the pioneers on the issues related to deep-learning mechanism in eastern China.
EVALUASI PROSES PEMBUATAN PATUNG JANGIR PADA UPT PSTKP BALI â€“ BPPT TAHUN 2014
Authors: Normal I Nyoman
Published: December 2023

The aims of this research that relate production process of jangir statue(p 11 cm, l 4 cm, t 14 cm) use stove size differently are: (1)To know the influence ofstove sizing to cost of goods manufactured loading jangir statue; (2) To know theinfluence of stove sizing to gross profit recognition jangir statue; and (3) To knowthe influence of stove sizing to inventory turnover calculationjangir statue. Theresearch results shew that: (1) The stove sizing influent of cost production loading jangir statue (p 11 cm, l 4 cm, t 14 cm). The decreasing trend ofcost of goods manufactured jangir statue (p 11 cm, l 4 cm, t 14 cm use midle size stove was 0,96%,and big size stove was 1,15%; (2) The stove sizing influent of gross profit recognitionjangir statue (p 11 cm, l 4 cm, t 14 cm). The bigger stove sizing cause bigger grossprofit jangir statue. The increasing trend ofgross profit jangir statue (p 11 cm, l 4cm, t 14 cm) use midle size stove was 7,05%, and big size stove was 15,06%; dan(3) The stove sizing did not influent of inventory turnover jangir statue (p 11 cm, l 4cm, t 14 cm). The small stove, the middle stove size, and the big stove result the sameinventory turnover, that is 21,43 times.
Tourism Marketing Management Strategy At The Department Of Tourism And Culture Of Trenggalek Regency
Authors: Gaung Perwira Yustika  , Muchlis Muhammad Arfan
Published: December 2023

Industry competition in Indonesia is currently very tight, especially in the world of tourism, where each region competes to highlight its uniqueness. With this very tight competition, the Tourism and Culture Office of Trenggalek Regency has developed a strategy for marketing management to promote tourism potential in the region. The aim of the tourism marketing management strategy is to increase the existing tourism potential in the area. This research method is descriptive and qualitative. The informants in this study were the Head of the Tourism Marketing Division, and the Head of the Tourism Promotion and Information Section. Data collection was carried out through direct observation, interviews and documentation. Data collection took place in the stages of data collection, data reduction, data presentation and drawing conclusions. The results of this study conclude that the implementation of the tourism marketing strategy is good, although still not optimal, tourism development is supported by official programs in the form of tourism promotion measures using advertising media or tools such as print media, electronic media and exhibitions.
Pengaruh Kemudahan Penggunaan, Harga Dan Promosi Terhadap Loyalitas Pelanggan Pada Pengguna Shopee
Authors: Arjuna Putra  , Muhammad Nur Fietroh
Published: December 2023

This study aims to examine the Effect of Ease of Use, Price and Promotion on Customer Loyalty for Shopee users. The population in this study is the people of Sumbawa City. The sample of this research is 100 respondents who have several criteria. The sampling technique used is Non Probability Sampling. The data analysis used was the classical assumption test, multiple linear regression test, hypothesis test (t/effect test) and the coefficient of determination test and processed using the SPSS 25 program. The results of this study indicate that there is a positive and significant influence on Ease of Use, Price and Promotion of Customer Loyalty
Kutau Martial Ritual Of Community In The Suro Village
Authors: Lidiantari Aulini , Muliati Roza , Nursyirwan  , Minawati Rosta
Published: December 2023

This paper discusses the kutau martial ritual in the people of Suro Village, Muara Beliti District, Musi Rawas Regency. Kutau is one of the ancestral heritage where there are rituals in practice that are carried out. Kutau is in the form of a traditional martial art that developed within the people of Suro Village. Using a qualitative approach, the purpose of this study was to find out the forms of rituals in kutau self-defense and the functions of the kutau rituals in the Suro community. Research data was collected from observation, interviews, and documentation. The data obtained was then analyzed using a ritual approach by Victor Turner and function by Talcot Parsons. The results of the study show that the kutau martial arts ritual is a communication medium for the kutau group and the ancestors who inherited the kutau knowledge, which is related to the beliefs of the Suro people. The sustainability of kutau is due to the achievement of the latency function of the kutau group, so that the system built is able to survive and adapt in society.
Application Of The Discovery Learning Model In Increasing Student Activity
Authors: Yasin Muhammad , Rusdianti Nasution Fira
Published: December 2023

The aims of this research are the urgency of implementing the Discovery Learning Learning Model in Islamic Religious Education Subjects at North Sangatta 1 Vocational School, what is the Process of Implementing the Discovery Learning Learning Model in Increasing Student Activities in Islamic Religious Education Subjects at North Sangatta 1 State Vocational School, and how to have a positive impact on students by implementing the Discovery Learning Learning Model in Islamic Religious Education Subjects. This research uses qualitative methods. Type of field research, where to obtain accurate data the researcher comes directly to the research location, namely SMK Negeri 1 Sangatta Utara, using a qualitative research approach. In this research, researchers used data collection techniques in the form of observation, interviews, documentation with descriptive techniques. In analyzing this data, the author uses data condensation, data presentation, and drawing conclusions or verification. The findings of this research are (1) the discovery learning model is very good at helping students easily understand the subject matter. (2) In the process of implementing the learning model using the discovery learning learning model using lesson plans as a reference, of course there are three parts, the first is the introductory part consisting of (orientation, apperception, motivation, and providing references), the second is the core part where the application of the discovery learning model is included in This section consists of (stimulation, problem statement, questions/problem identification, data collection, data management, proof and drawing conclusions). (3) The positive impact on students from the application of the discovery learning model in Islamic Religious Education subjects is: Can improve students' ability to solve problems, Encourages active involvement of students, and this Learning Model prepares students for independent learning.
The Strategic Role Of Article 6 Of Law No 41 Of 2004 In The Management Of Term Waqf: A Progressive Review Of Islamic Economic Renewal
Authors: Pratama Tommy , Syahmirwan  , Ar Rosyit Achmad Nasrul Waton
Published: December 2023

Waqf is a form of worship and is also one of the pillars of the Islamic economy which has the potential to improve community welfare and overcome the problem of poverty. One of the laws governing waqf in Indonesia is Law No. 41 of 2004. Futures Waqf is an innovation in modern Islamic economics, aligning Islamic economic principles with contemporary developments. This research provides an understanding of the evolution of Islamic economics and efforts to encourage the implementation of Islamic economic principles in ever-changing global dynamics. In this research the author uses a qualitative method with a normative juridical approach. This law is the basis that waqf can be forever and can also have a term. This is very different from what is regulated by Islamic waqf law which tends to be less directed towards economic empowerment of the people and is only used for religious activities such as building mosques, prayer rooms, schools and cemeteries. This evaluation provides an in-depth impact on how the effectiveness of this regulation can increase the economic benefits of Term Waqf, encourage sustainable economic growth, and support the achievement of sharia economic development goals in Indonesia.
Implementation of Value Added Tax Policy On E-Commerce Transactions in Bekasi City (Case Study of the West Bekasi Pratama Tax Service Office)
Authors: Soi Veronika
Published: December 2023

This study aims to analyze how the implementation of the Value Added Tax policy for e-commerce transactions in Bekasi City, as well as to analyze the obstacles and efforts related to the implementation of this Value Added Tax policy. The data analysis method in this paper uses a qualitative approach with the specificity of descriptive theory used to support the successful implementation of Georges Charles Edward III's theory which consists of 4 indicators, (1) Communication, (2) Resources, (3) Disposition, (4) Bureaucratic Structure. There are obstacles in the implementation of the Value Added Tax policy on e-commerce transactions in Bekasi. The address of the Taxpayer is invalid, the Taxpayer who has moved address but the NPWP has not been changed, the letter from the Tax Service Office does not reach the Taxpayer, and the lack of understanding of taxation . The results of this study was that there was an obligation to pay Value Added Tax on e-commerce transactions, because basically an e-commerce transaction is not different from convetional transaction only there is distinguishing trade mechanism. So there is necessary adtments to several parties and co-operation.
The Influence of Service Quality, Taxpayer Awareness, and Modernization of the Tax Administration System on Individual Taxpayer Compliance at the Pondok Aren Pratama Tax Service Office
Authors: Debora Liani Trinita , Zaya Amer Shebl
Published: December 2023

The Influence of Service Quality, Taxpayer Awareness and Modernization of the Tax Administration System on the Compliance of Individual Taxpayers Registered at KPP Pratama Pondok Aren. The observation method used is quantitative method, the research data is obtained through a questionnaire. The sampling technique uses Incidental Sampling. The results of this study indicate that the effect of service quality, taxpayer awareness and taxation system modernization is significant on taxpayer compliance, taxpayer awareness and modernization of the tax administration system on individual taxpayer compliance registered at KPP Pratama Pondok Aren, explaining what are the obstacles encountered and provide solutions to overcome these obstacles. Based on the observations made by the author, that the influence of service quality, taxpayer awareness and modernization of the tax administration system on the compliance of individual taxpayers registered at the Pondok Aren Tax Office in accordance with the legislation. Through observations, it can be concluded that the effect of service quality, awareness and modernization of the tax administration system must be maximized and must be further improved so as to increase individual taxpayer compliance.
Implementation of the E-Bupot System in Order to Provide Convenience to Taxpayers in Fulfilling Article 23 Income Tax Obligations at the KPP Bekasi City Intermediate
Authors: Hikmah Nurul
Published: December 2023

This research aims to examine the implementation of the e-bupot application in order to provide convenience for taxpayers in fulfilling income tax obligations under article 23. This research was conducted at the Bekasi City Intermediate KPP which is located at M Gold Tower UG Floor, 9, 10 Jalan KH Noer Ali RT.7/RW3, Pekayon Jaya, South Bekasi District, Bekasi City, West Java 17148. This research is descriptive qualitative research which aims to provide an objective picture of the actual situation of the object under study. Data was collected using interviews, observation and documentation methods. Informants in this research were determined using purposive techniques, informants in this research were service staff, taxpayers and academics. The research results show that in the aspect of system quality, e Bupot's ability to facilitate PPH 23 reporting, in terms of information quality, e Bupot has complete information regarding taxpayer requirements, and the type of withholding proof has good information, related to user satisfaction assessed from the aspect of minimal obstacles , each informant has different information such as ownership of e-certificates, minimal knowledge of taxpayers, and the most common are technical errors.
Analysis of the Modernization of the Tax Administration System in the Context of Optimizing Advertisement Taxes in the District Tax Collection Service Unit. Gambir 2021-2022
Authors: Fatmelia Henny Rizky
Published: December 2023

In the optimization of advertising tax, there still a lack of awareness among the public of taxpayers regarding the advertising tax, and some advertising tax participants either evade or delay their payment obligations. The development of a modernized administration system aims to establish an efficient bureaucracy, particularly to enhance tax revenue. The objective of this research is to examine the modernization of the tax administration system to optimize advertising tax in the tax collection service unit of Gambir Sub-District in 2021-2022. The author applies Diana. Sari’s theory of tax administration modernization, as discussed by Imam Juhadi, and incorporates Person Horoda’s theory of advertising tax optimization. This study adopts a descriptive qualitative research approach. In 2021, the revenue from advertising tax in the tax collection service unit of Gambir Sub-district reached a percentage of 72.71%, while in 2022, it reached 68.89% of its target. It can be noted that in 2022, there was a significant deviation from the predetermined target due to various reasons. Several challenges were encountered by both a officials and taxpayers in fulfilling their obligations.
"Efficiency in science is first of all fundamentality": a quantitative history through the prism of the personal archive of Academician I.D. Kovalchenko
Authors: Borodkin Leonid
Published: December 2023

The year 2023 marks the 100th anniversary of the birth of academician I.D. Kovalchenko, an outstanding Soviet and Russian historian. This article is devoted to important aspects of his academic and organizational activities in the field of application of mathematical methods and computers in historical research. This is a look through the prism of the academician's personal archive. The article describes the discussion on the problems of modeling historical processes and phenomena, in which academician I.D. Kovalchenko participated, and also reveals his position on the analysis of alternatives to the historical process. As the main example of an alternative historical situation analyzed by I.D. Kovalchenko, the "Great Turning Point" is considered, the end of the 1920s. Bukharin's alternative is considered as actually existing. The materials of Academician Kovalchenko's personal archive clearly demonstrate his conviction that the application of mathematical methods in historical research is not a "purely technical" task, he formulates a number of methodological issues that arise in this kind of interdisciplinary research. The materials of the academician's personal archive reveal an important feature of his research – attention to the correctness of the using mathematical and statistical methods. While working on his doctoral dissertation, he tested its methodology at a seminar of the specialized Department of the Faculty of Mathematics of Moscow State University. The work on the monograph (jointly with L.V.Milov) on the formation of the All-Russian agricultural market gave rise to correspondence with N.S. Chetverikov, a famous Soviet and Russian statistician of the Chuprov school, who developed, in particular, mathematical methods for analyzing dynamic series. In this correspondence, controversial issues of statistical methodology were clarified. Quantitative history, the founder of which in Russia is academician I.D. Kovalchenko, is again an urgent trend today. In the 21st century, there has been an actual increase in interest in Data Science, the traditional core of which is statistical methods.
HALKLA İLİŞKİLERİN GELİŞEN ROLÜ VE ÖNEMİ: İNTERNET TABANLI MEDYA ARAÇLARI İLE HALKLA İLİŞKİLERİN PAZARLAMADAN AYRIŞMASI
Authors: EROL BOYACI Gülay
Published: December 2023

İnternet çağı ile yepyeni bir anlam ve önem kazanan halkla ilişkiler, işletmeler için zorunlu bir işletme fonksiyonu halini almış ancak literatürde pazarlama fonksiyonundan ayırmak kolay olmamıştır. Bu ayrımı yapmayı kolaylaştırmak amacıyla bu çalışmada, çevrim içi medya araçlarının kullanım amaçları ele alınarak halkla ilişkiler fonksiyonunun ayırt edici özellikleri ve önemi tartışılmıştır. Bu doğrultuda, internet tabanlı iletişim araçlarından web siteleri, sosyal medya platformları, bloglar (çevrim içi günlükler) ile podcastlar (sesli bloglar) ve mobil uygulamalar, marka/işletme odaklı kurumsal halkla ilişkiler ve ürün odaklı tüketici halkla ilişkileri açısından ayrı ayrı değerlendirilmiştir. Yapılan incelemeler sonucunda her iki halkla ilişkiler faaliyetleri için çevrim içi medya araçlarının kullanımının pazarlama faaliyetlerindeki kullanımlarından farklı olarak, satışları desteklemek veya artırmak amaçlı olmadığı görülmüştür. Sonuçlar, incelenen medya araçları arasında çevrim içi halkla ilişkiler faaliyetleri için ideal aracın sosyal medya platformları olduğunu ortaya koymuştur. Öte yandan, işletmeleri hedef kitlelerine yakınlaştıran ve onlar ile niş ölçekte iletişim kurabilme imkânı sunan internet temelli medya araçlarının aynı zamanda önemli bazı sorunlar da doğurduğu görülmüştür. Son olarak literatürde yer alan bilgiler ışığında, yalnızca halkla ilişkiler uygulamaları ele alınarak pazarlama fonksiyonunun temel amacına kıyasla nasıl farklılaştıklarının tartışılması ile sosyal medya platformlarının tek başlık altında ele alınmış olması bu çalışmanın kısıtlarını oluşturmaktadır.
YERE BAĞLILIĞIN VE KENT KİMLİĞİNİN BİR MEKÂN ÜZERİNDEN İNCELENMESİ: İSRAİLEVLERİ (DİKMEN YAPI KOOPERATİFİ) ÖRNEĞİ
Authors: KALAYCI Tuğçe , YILDIRIM Kemal , MUTDOĞAN Alım Selin
Published: December 2023

Bu çalışmada, kullanıcıların İsrailevlerini (Dikmen Yapı Kooperatifi) tercih etme nedenleri, yaşadıkları mekâna ve kent kimliğine yönelik bağlılık ve tutumlarının belirlenmesi amaçlanmıştır. Bu sebeple, araştırmanın amacına uygun olarak ‘Yere Bağlılık Ölçeği’ ve ‘Kent Kimliği Ölçeği’ kullanılarak kullanıcıların bağlılık ve tutumları belirlenmiştir. Yapılan anket sonucu İsrailevlerinde (Dikmen Yapı Kooperatifi) yaşayan 47 konut kullanıcısından elde edilen veriler istatistiksel yöntemlerle değerlendirilmiş ve bulgular kısmında sistematik bir sırayla ele alınmıştır. Sonuç olarak, yere bağlılık düzeylerinin ve kent kimliği tutumlarının bir mekân üzerinden incelendiği bu çalışmada mekânı deneyimleyen kullanıcıların yere bağlılık düzeyleri ve kent kimliği tutumları arasında pozitif ve anlamlı bir ilişki olduğu ortaya çıkmıştır. Bu, mekânın sadece fiziksel bir yapı olmadığını, aynı zamanda kent yaşamının bir parçası olduğu görülmüştür. Aynı zamanda mekân tasarımında kullanıcıların rolünün büyük önem taşıdığı tespit edilmiştir.
A hepatocyte-specific transcriptional program driven by Rela and Stat3 exacerbates experimental colitis in mice by modulating bile synthesis
Authors: Singh Jyotsna , Sarkar Binayak , Yadav Mohit , Deka Alvina , Markandey Manasvini , Sanyal Priyadarshini , Nagarajan Perumal , Gaikward Nilesh , Ahuja Vineet , Mohanty Debasisa , Basak Soumen , Gokhale Rajesh S
Published: December 2023

Hepatic factors secreted by the liver promote homeostasis and are pivotal to maintain liver-gut axis. Dysfunctional interactions between the liver and the intestine stimulate varied pathological outcomes through its bidirectional portal communication for example an aberrant bile acid metabolism has been reported in inflammatory bowel disease (IBD). However, the molecular mechanisms underlying these crosstalks that perpetuate intestinal permeability and inflammation remains obscure. Here, we identify a novel hepatic gene program regulated by Rela and Stat3 that accentuates the inflammation in an acute experimental colitis model. Hepatocyte specific ablation of Rela and Stat3 reduces the levels of primary bile acids in both liver and gut and shows restricted colitogenic phenotype. On supplementation of chenodeoxycholic acid (CDCA), knock-out mice show enhanced colitis-induced alterations. This study provides persuasive evidence for the development of multi-organ strategies for treating IBD and identifies a hepatocyte-specific rela-stat3 network as a promising therapeutic target.
Identification and characterization of the karrikins signaling gene SsSMAX1 in Sapium sebiferum
Authors: Ni Fang , Shah Faheem Afzal , Ren Jie
Published: December 2023

SUPPRESSOR OF MAX2 LIKE 1 (SMAX1) is a member of the SUPPRESSOR of MAX2 1‑LIKE family of genes and is known as a target protein of KARRIKIN INSENSITIVE2 (KAI2)-MORE AXILLARY BRANCHES2 (MAX2), which mediates karrikin signaling in Arabidopsis. SMAX1 plays a significant role in seed germination, hypocotyl elongation, and root hair development in Arabidopsis. SMAX1 has not yet been identified and characterized in woody plants. This study identified and characterized SsSMAX1 in Sapium sebiferum and found that SsSMAX1 was highly expressed in the seed, hypocotyl, and root tips of S. sebiferum. SsSMAX1 was functionally characterized by ectopic expression in Arabidopsis. SsSMAX1 overexpression lines of Arabidopsis showed significantly delayed seed germination and produced seedlings with longer hypocotyl and roots than wild-type and Atsmax1 functional mutants. SsSMAX1 overexpression lines of Arabidopsis also had broader and longer leaves and petioles than wild-type and Atsmax1, suggesting that SsSMAX1 is functionally conserved. This study characterizes the SMAX1 gene in a woody and commercially valuable bioenergy plant, Sapium sebiferum. The results of this study are beneficial to future research on the molecular biology of woody plants.
A qualidade como variável estratégica nas organizações modernas
Authors: Da Costa Fernando José Pereira , Rodrigues Manoel Gonçalves
Published: December 2023

A empresa moderna encontra-se inserida num contexto ambiental caracterizado por elevados e crescentes níveis de instabilidade e graus de incerteza muito elevados no que diz respeito à continuidade de suas atividades. Este clima ambiental adverso está relacionado à ocorrência de determinados eventos que tornam hoje o meio envolvente empresarial bem mais volúvel do que fora num passado relativamente próximo em termos históricos, a saber: a globalização, o advento de um novo paradigma em termos energéticos e meio ambientais, o acelerado desenvolvimento tecnológico, a desregulação das economias e a acirrada concorrência a nível dos mercados globais. Com isto, torna-se cada vez mais difícil a inserção da empresa no âmbito de uma configuração contextual em que a incerteza é o principal atributo. Assim sendo, a empresa necessita cada vez mais de um suporte estratégico que lhe viabilize a atividade em envolventes turbulentas e lhe possibilite alcançar níveis elevados de capacitação tecnológica. Como resultado direto desse processo ter-se-ia o incremento da produtividade com o consequente aumento da competitividade organizacional. É neste ponto que ganha corpo a ideia da Qualidade, isto é Qualidade Total como variável estratégica básica das organizações no que se refere à sua atuação em um entorno caracterizado por uma instabilidade cada vez mais notória. Propõe-se a adoção de um conceito reformulado de Qualidade, ou seja, como suporte estratégico das organizações, que passam a lidar com uma envolvência cada vez mais incerta.
Factors Affecting Pulmonary Artery Catheterisation in Patients Undergoing Coronary Artery Bypass Grafting: A Cross-sectional Study
Authors: Basak Neeta , Ghosh Kakali , Banu Parvin , Biswas Arunava , Naser Syed Mohammed , Dasgupta Chaitali Sen
Published: December 2023

Introduction: The Pulmonary Artery (PA) catheter continues to be used for monitoring haemodynamic parameters in the majority of patients undergoing Coronary Artery Bypass Grafting (CABG) surgeries, despite concerns raised regarding costeffectiveness and safety issues. Sometimes, placement takes longer or is difficult just by looking at the pressure waves. There are several factors that may influence the duration of Pulmonary Artery Catheter (PAC) insertion. Aim: To determine the factors affecting PAC in anaesthetised patients undergoing elective CABG. Materials and Methods: A single-centred, cross-sectional study was conducted in the Cardiothoracic and Vascular Surgery operation theartre at IPGME&R and SSKM Hospital, Kolkata, India including 138 patients aged 35-65 years of either sex undergoing elective CABG surgery in a tertiary care hospital in Eastern India. The attempt to perform successful first-time catheterisation or failure of the PAC done by a resident cardioanaesthesiologist was noted, as well as whether catheterisation was successfully done within a specified time or not. This time was obtained as the 75th percentile of the time taken for catheter placement for the first 30 cases catheterised in the first attempt. For ease of analysis, all first attempt successful cases were considered as Group A (n=125), and all first attempt failure cases as Group B (n=13). The study data on various parameters were recorded on a proforma and summarised as the mean and standard deviation for normally distributed numerical variables, median and interquartile range for skewed numerical variables, and counts and percentages for categorical variables. A p-value <0.05 was considered statistically significant. Results: A total of 138 patients were analysed during the entire study. There was a predominance of male patients (82.6%) with a male-to-female ratio of 114:24. The first attempt failure rate of successful PAC was 13 out of 138, i.e., 9.42% (95% confidence interval 4.55% to 14.29%). The cut-off time for the procedure as the 75th percentile of the first 30 successful cases is 269 seconds. The number of cases in which it was done within this time was 109 cases, i.e., 78.99%. There was a significant difference (p<0.05) in terms of body weight, body surface area, and neck length between the two groups. Conclusion: Increased body weight and increased body surface area are significant factors associated with difficult PAC placement. On the other hand, short neck length is a significant factor for taking more time in the placement of the catheter.
Prevalence of Anti-Dense Fine Speckled 70 Antibodies in Systemic Autoimmune Rheumatic Diseases and Healthy Controls: A Cross-sectional Study
Authors: Mohan MVNL Ram , Sudhaharan Sukanya , Rajasekhar Liza , Teja VD , Talasila Sudha
Published: December 2023

Introduction: Recognition of Dense Fine Speckled (DFS) Antinuclear Antibody (ANA) pattern is challenging as it is frequently confused with speckled or homogeneous patterns. Identification and confirmation of DFS pattern is important as it is more often seen in healthy individuals, routine laboratory referrals with relatively lesser prevalence in Systemic Autoimmune Rheumatic Diseases (SARD). As there is limited data on the prevalence of DFS pattern in Indian population, present study determined the prevalence and clinical significance of DFS pattern followed by anti-DFS 70 Enzyme Linked Immunosorbent Assay (ELISA) for confirmation. Aim: To estimate the prevalence of anti-DFS 70 antibodies in ANA screening tests, SARD, and healthy individuals by Indirect Immunofluorescence (IIF) screening and confirmation by anti- DFS 70 ELISA. Materials and Methods: A cross-sectional study was conducted over a period of 15 months from January 2017 to April 2018 at Nizams Institute of Medical Sciences, a tertiary care institute in Hyderabad, Telangana, India. A total of 7,550 serum samples were tested by IIF during the study duration. Sera displaying DFS pattern was tested for anti-DFS antibodies and anti-Extractable Nuclear Antigen (ENA) antibodies by ELISA. A total of 49 patients from rheumatology department satisfying SARD criteria and 184 healthy patients were also tested for anti-DFS antibodies. Results: Anti-DFS 70 antibodies were seen in 0.47%, 16.3%, 39.6% among routine ANA screening referrals, SARD patients and healthy individuals, respectively. DFS 70 antibodies were positive in 60% of DFS IIF positive samples with none of them showing anti-ENA positivity or clinical evidence of SARD. Anti- DFS 70 positivity was more commonly seen in younger patients. Anti-DFS antibodies were significantly more common in healthy individuals compared to SARD patients (p -value=0.0022). Conclusion: It is important to confirm DFS IIF pattern with a specific ELISA as isolated DFS antibodies are frequently associated with non SARD conditions.
Analysis of C-reactive Protein and Ferritin as Inflammatory Marker and their Association with the Severity of COVID-19: A Cross-sectional Study
Authors: Thodi Nasma Mankara , Peruvankuzhiyil Farija , Vasantha Sandhya Chandrasekharan , Pulloor Niyas Kudukkil , Parambath Nikhil Vinod
Published: December 2023

Introduction: Virus-induced hyperinflammation can lead to mild symptoms or multiorgan dysfunction in severe Coronavirus Disease-2019 (COVID-19). In contrast to moderate conditions, severe COVID-19 exhibits higher levels of inflammatory markers, and tracking these markers may enable early disease detection and a good prognosis. The role of ferritin and C-reactive Protein (CRP) as inflammatory markers is evident in literature. However, it has not been proven whether this differs between patients who COVID-19 and non COVID-19 patients. Aim: To compare CRP and ferritin levels between COVID-19 positive patients and apparently normal Reverse Transcription- Polymerase Chain Reaction (RT-PCR) negative individuals, and to assess their association with COVID-19 severity. Materials and Methods: A cross-sectional study was conducted in isolation wards and Intensive Care Units (ICUs) at a Tertiary Care Hospital in Government Medical College Manjeri, Kerala, India. The study was conducted over six months, from August 2020 to January 2021. A total of 70 patients diagnosed with COVID-19 and 35 RT-PCR negative healthy subjects, aged between 18-75 years, were included. CRP and ferritin levels were measured and compared between COVID-19 patients and apparently normal RT-PCR negative individuals. The quantitative parameters were evaluated using the Mann-Whitney U test, and the categorical values were analysed using the Chi-square test. Statistical significance was defined as a p-value of ≤0.05. Results: All COVID-19 patients were between the ages of 18 and 75 years, with a mean age of 55.03±13.01 years in symptomatic COVID-19 positive (group A), 57.89±10.85 years in COVID-19 positive with pneumonia (group B), and 40.89±15.89 years in the control group (group C). In group A, there were 18 (51%) males and 17 (49%) females, while in group B, 23 (66%) were males and 12 (34%) were females. Out of the 35 control group participants, 17 (49%) were males and 18 (51%) were females. No significant differences were reported when comparing the genders of patients with healthy subjects. The results of the present study showed significantly higher median values of CRP (34.90) and ferritin (652.20) in COVID-19 patients compared to non-COVID-19 individuals, which were 4 and 116, respectively (p-value<0.001). Conclusion: Increased levels of CRP and ferritin in COVID-19 patients suggest that they can be used as inflammatory markers for the early detection of the disease. Moreover, higher levels in individuals with severe symptoms, as opposed to those with mild symptoms, define their involvement in illness severity.