bluuebunny/crossref_metadata_2025 huggingface dataset:
Defining the Dialogue between Sciences: A View on Transdisciplinary Perspective in the Human Sciences
Authors: Rimondi Giorgia , Veronese Marco
Published: September 2018

Aim/Purpose: The authors argue that interdisciplinarity, together with the more recent concept of transdisciplinarity, can be seen as a coherent attempt not so much to reassemble the fragmented structure into a whole, as to create a fruitful collaboration and integration among different disciplines that takes into account their specificity.

Background: At the threshold of the Modern Age, a series of paradigm shifts in Western thought caused its fragmentation into a variety of academic subdisciplines. Such diversification can be considered the result of epistemological shifts and changes in the division of intellectual labor.

Contribution: Which semantic horizons can this new approach open, and on which theoretical foundations could a dialogue between disciplines be produced? The growing importance of this problem is evidenced by the emergence, during the last decades, of philosophical reflections on the interactions among different research fields.

The paper aims to contribute to the contemporary discussion of the need to overcome boundaries between disciplines. Consequently, it has both a methodological and theoretical impact, since all branches of knowledge aspiring to go beyond their traditional theoretical boundaries would benefit from a coherent theoretical perspective which tries to reconceptualize the transfer of knowledge from one field to another.

Findings: The possibility of transdisciplinarity in modern science finds its theoretical premise in M. Foucault’s seminal work on the organization of knowledge, The Order of Things, which hinted at the existence of gaps in the grid of knowledge, leading, as a result, to the possibility of creating transdisciplinary connections.

Future Research: The authors’ critical discussion of transdisciplinarity aims to revive the French epistemological tradition that in the last decades has often been rejected by researchers as not being rigorous nor analytical. This choice is motivated by the belief that, despite such evident defects, at its bottom lies a genuine theoretical intention that does not take for granted the possibility of transcending the usual division of intellectual work. In addition, the authors offer a brief account of the Russian conception of transdisciplinarity, relatively little studied in the West, which is presumed to integrate and solve the difficulties of other similar models.
Sentiment Classification of Chinese Financial Reviews
Authors: Zhong Fahai , Yuan Hang , Li Mengnan , Luo Ronghui
Published: September 2018

In order to explore the method of sentiment classification of Chinese text, this paper takes the Chinese comments of financial sector as the main research object and carries out text sentiment classification tasks. This paper proposes to initialize the word embedding with dictionary, to solve the problem that some words have opposite sentimental trendencies but similar distributed representation. Three commonly used evaluation indexs and their average value(AvgScore), the accuracy of classifier, the average recall rate and MacroF1, were given to evaluate the model. Through comparative analysis to explore the factors that influence the effect of classifier, this paper uses CNN, LSTM, GRU as the substructer and constructs a total of 9 models with different structures and depths for comparative study. Based on the top three models on AvgScore, this paper studies the method of initializing the word embedding with sampling and random perturbation technique. The results show that the sampling technique has the greatest impact on the classifier effect. Among the different sampling techniques, AvgScore difference by 1.1% to 38.3%. The best results can be obtained from the mix use of downsampling technique in majority and few oversampling technique. The classifier obtained by word embedding with sentiment dictionary is better than using other word vectors. Its highest accuracy rate, MacroF1, AvgScore respectively are 82.37%, 77.26% and 77.62%, and the other highest are 82.19%, 76.73%, 77.08%. In this paper, the top three classifiers with the highest AvgScore are selected to build the classifier in ensemble approach. The accuracy of the final ensemble method classifier is 84.00%, the average recall is 74.58%, the Macro F1 is 79.50%, and the AvgScore is 79.36%.
From Parametric Trace Slicing to Rule Systems
Authors: Reger Giles , Rydeheard David
Published: September 2018

Parametric runtime verification is the process of verifying properties of execution traces of (data-carrying) events produced by a running system. This paper continues our work exploring the relationship between specification techniques for parametric runtime verification. Here we consider the correspondence between trace-slicing automata-based approaches and rule-systems. The main contribution is a translation from quantified automata to rule-systems, which has been implemented in SCALA. This then allows us to highlight the key differences in how the two formalisms handle data, an important step in our wider effort to understand the correspondence between different specification languages for parametric runtime verification.
KRİZ İLETİŞİMİNDE MESAJ STRATEJİLERİ: ERMENEK KÖMÜR MADENİ KRİZİNE YÖNELİK UZMAN GÖRÜŞLERİNİN İNCELENMESİ
Authors: MERT İbrahim Sani , AYDIN Oğuz Bayram
Published: September 2018

﻿Krizde
paydaşlara verilen mesajlar, krizin paydaşlar üzerindeki etkisi ve dolayısıyla
da kriz yönetiminin başarısı açısından önemlidir. Kriz iletişimi çalışmaları
incelendiğinde, mesaj stratejilerini içeren teorilerin daha çok ön plana
çıktığı görülmektedir. Bu nedenle, paydaşlara yönelik mesaj stratejilerinin
doğru seçilmesi önemlidir. Kamuoyunu bilgilendirmeye yönelik mesajların
incelendiği bu çalışmada veriler, can kaybı ve yaralanmaların yaşandığı Ermenek
kömür madeni krizine (28 Ekim 2014) yönelik 33 uzmanla yapılan görüşmelerle
toplanmıştır. Araştırma verileri içerik analizi yöntemiyle incelenmiştir. Elde
edilen bulgulara göre; bilgilendirmenin niteliği, krizden etkilenenlerin duygu
durumları, toplumun değerleri, kabullenme, tazminat ve sorumluluk konularının
can kaybı ve yaralanmaların yaşandığı kriz durumlarında, paydaşlara iletilecek
mesajların oluşturulmasında dikkat edilecek önemli hususlar olduğu
belirlenmiştir.
DOĞRUDAN YABANCI SERMAYE YATIRIMLARININ BORSA VE REEL SEKTÖRDE FİRMALARA ETKİSİ: GELİŞMEKTE OLAN ÜLKELER ÜZERİNE EŞBÜTÜNLEŞME VE NEDENSELLİK ANALİZİ
Authors: POLAT Müslüm
Published: September 2018

﻿Bu
çalışmanın amacı, gelişmekte olan ülkelerde doğrudan yabancı sermaye
yatırımlarının (DYSY) reel sektörde ve borsada firmalara etkisini ölçmektir. Bu
amaçla gelişmekte olan on ülkede 2002 – 2015 dönemine ait yıllık veriler ile
panel veri analizi yapılmıştır. Panel veri analiz yöntemlerinden Westerlund
(2006) eşbütünleşme, AMG katsayı tahmincisi ve Emirmahmutoğlu-Köse nedensellik
testi kullanılmıştır. Analizler neticesinde değişkenlerin eşbütünleşik
oldukları belirlenmesine rağmen DYSY’lerin borsada firmalara pozitif etkisi
anlamlı bulunurken reel sektördeki etkisi anlamlı bulunmamıştır. Bununla
birlikte ülkelere ait etkilerin, her iki modelde de ülkeden ülkeye farklılık
gösterdiği belirlenmiştir. Ayrıca firmanın piyasa değerinden DYSY’ye doğru ve
DYSY’den de reel sektöre doğru nedensellik olduğu tespit edilmiştir.
Perfil epidemiológico das intoxicações por plantas tóxicas e domissaneantes notificadas em Goiás no período 2011 a 2015.
Authors: Silva Larissa Amorim , Nascimento Henrique Augusto , Silva Lorena De Oliveira , Machado Hellen Caroline Pereira , Prados Victória Oliveira , Morais Lanna Tarce Gonçalves de , Maya Ana Carolina Lobato , Oliveira Raphael Rocha de
Published: September 2018

Objetivos: Busca-se discutir as intoxicações por produtos químicos, domissaneantes e plantas tóxicas notificadas no estado de Goiás no período de 2011 a 2015. Métodos:Trata-se de um estudo epidemiológico descritivo, cujos dados foram obtidos por meio de consulta à base de dados Sistema de Informações de Agravos e Notificação disponibilizada pelo Departamento de Informática do Sistema Único de Saúde. Foi utilizado o Sistema de Informação Geográfica gratuito e realizadas técnicas de geoprocessamento para visualizar, editar, criar e analisar os dados dos mapas de referência. As variáveis utilizadas foram: município de notificação, sexo, faixa etária, circunstância, zona de residência, escolaridade, tipo de exposição e evolução do quadro. Resultados: Observou-se uma prevalência das intoxicações por produtos químicos (46.16%), seguidas por domissaneantes (44.70%) e por plantas tóxicas (9.13%). As cidades que apresentaram um maior número de notificações foram Goiânia, Formosa, Anápolis, Rio Verde, Valparaíso de Goiás e Jataí. As intoxicações foram mais prevalentes em mulheres (53.23%). Os maiores índices estão nas faixas etárias de 01 a 04 anos (28.05%) e de 20 a 39 anos (38.55%). A circunstância está associada com a faixa etária, sendo de forma geral, a intoxicação acidental mais frequente. Há maior número de casos na zona urbana (91.83%). A exposição aguda-única é mais frequente e a maioria dos casos evoluíram para cura sem sequela. Conclusão: Portanto, os resultados se justificam pelo armazenamento, uso e disponibilização inadequados de produtos químicos e desconhecimento do potencial tóxico de algumas plantas.
UNIVERSIDAD AUTÓNOMA DE NUEVO LEÓN SOCIALMENTE RESPONSABLE CON EL MEDIO AMBIENTE
Authors: Ancer Rodríguez Jesús
Published: September 2018

Al inicio del siglo XXI, las sociedades afrontan problemas inéditos en lo referente al ambiente, el desarrollo, la equidad y la gobernanza, cuyas magnitudes amenazan drásticamente las formas de relación y sobrevivencia de los seres humanos, así como la integridad del conjunto de los ecosistemas del planeta. El más relevante de todos ellos, en el rubro ambiental, tanto por su dimensión global como por su complejidad, es el cambio climático.

A lo anterior se suman problemas críticos de carácter social, tales como el estancamiento económico, la precariedad laboral, la pobreza extrema, el desorden en el uso territorial y el abandono rural, entre otros, todo ello como expresión de un proyecto civilizador que no solo agranda estos fenómenos, sino que también los propaga. Para afrontar los retos impostergables de esta coyuntura es necesario avanzar en nuevos paradigmas, construidos en el campo multidisciplinario, que logren diseñar propuestas y acciones orientadas a impulsar un desarrollo sustentable en su perspectiva holística.
EVALUACIÓN DEL AUMENTO EN PESO DE CERVATOS COLA BLANCA ALIMENTADOS CON DIFERENTES FÓRMULAS LÁCTEAS
Authors: González Saldívar Fernando N. , Ontiveros Chacón Juan C. , Uvalle Sauceda José I. , Moreno Degollado Gustavo , Kawas Garza Jorge Ramsy
Published: September 2018

El estudio se desarrolló en el Centro de Mejoramiento Genético del Venado Cola Blanca del Centro de Producción Agropecuaria UANL, en el que se evaluaron los pesos al nacimiento y el crecimiento de cervatos de venado, mediante el registro de medidas corporales y de peso durante el periodo de lactancia. Para ello se formaron tres grupos: el primero se alimentó con el sustituto de leche Kitzenmilch®; el segundo con Lactoplex® y el tercero con leche de cabra, a partir de una rutina de alimentación predeterminada. Se realizaron mediciones corporales de largo total, circunferencia de tórax, altura a la cruz, entre otras, las cuales se correlacionaron con el peso y la edad. El promedio de peso al destete fue de 17.22 ± 3.69 kg para todos los grupos, con diferencias significativas entre el conjunto alimentado con leche de cabra = 21.21 ± 1.98 kg, con respecto a los que ingirieron Lactoplex® y Kitzenmilch® (P ≤ 0.05). Además, se determinaron diferencias significativas en los alimentados con Lactoplex®, 16.73 ± 1.56 kg y Kitzenmilch®, 13.88 ± 2.68 kg (P ≤ 0.05); no así entre hembras y machos (P ≥ 0.05). Se concluye que los cervatos que consumieron leche de cabra tuvieron el mayor crecimiento, con diferencias significativas en relación con los otros grupos de crianza.
Impacto del ingreso y carencias sociales sobre el consumo de carne en México
Authors: Huerta-Sanabria Sandy , Arana-Coronado Óscar Antonio , Sagarnaga Villegas Leticia Myriam , Matus-Gardea Jaime Arturo , Brambila Paz Jose de Jesus
Published: September 2018

El consumo de carne es importante para el ser humano, debido a las bondades proteicas de alto valor biológico que este alimento contiene. Además del ingreso existen otras variables como las carencias sociales, las cuales también determinan el consumo de carne. Identificar a los consumidores de carne en grupos económicos, contribuirá a entender la relación que tienen el ingreso y la privación social con el consumo de este bien. En julio del año 2014, se realizó una encuesta exploratoria con una muestra de 429 familias mexicanas, los datos son de carácter mixto, apoyándose de un cuestionario de 43 preguntas, de las cuales 20 fueron diseñadas bajo la metodología de la medición multidimensional de la pobreza del CONEVAL, a fin de detectar el índice de privación social de los consumidores encuestados. Se aplicó una prueba de F para comprobar homogeneidad de varianzas en el consumo semanal de carne de los tres grupos económicos detectados (vulnerables por carencias sociales, pobres multidimensionales moderados y pobres multidimensionales extremos) por último, se realizó la prueba T de Student para comprobar si existe diferencia de consumo de carne entre los tres grupos económicos. Los resultados demostraron que efectivamente existe diferencia de consumo para la carne de res, cerdo y pollo entre el grupo vulnerable por carencias sociales y pobre multidimensional extremo con una t de 2.8254, 2.686 y 2.2367 respectivamente. Por lo anterior se concluye que, efectivamente la privación social y el ingreso influyen directamente en el consumo semanal de carne.
DISTURBANCE OF THE PROGESTERONE AND ITS METABOLITES SYNTHESIS IN THE DEVELOPMENT OF NEUROLOGICAL DISORDERS IN CHILDREN AFTER CYTOMEGALOVIRUS INFECTION DURING PREGNANCY
Authors: Dovzhikova I. V. , Andrievskaya I. A. , Ishutina N. A. , Gorikov I. N. , Medvedeva S. V. , Lutsenko M. T.
Published: September 2018

Cytomegalovirus (CMV) infection is one of the causes of congenital neurological disorders and the virus itself is the most common viral  agent causing an imbalance in the production of placenta  progesterone and its neuroactive metabolites – allopregnenolone and 5α-dihydroprogesterone. The aim was to evaluate the concentration  of progesterone and its metabolites – 5α-dihydroprogesterone and  allopregnenolone – in placenta during exacerbation of CMV infection  in the first trimester of pregnancy, and the impact of these  disturbances on the development of neurological disorders in children. We examined 30 pregnant women with exacerbation of  CMV infection in the first trimester of pregnancy and 30 pregnant  women with latent disease; and later their newborns. The enzyme  immunoassay was used to determine  concentration of progesterone  in placenta; the histochemical method – to determine 5α-dihydroprogesterone and allopregnenolone. Newborns underwent  neurosonography studies. Exacerbation of CMV infection in the first  trimester of pregnancy decreased progesterone in placenta by 1.3  times, 5α-dihydroprogesterone – by 1.73 times and allopregnenolone – by 2 times. Ultrasound examination of the brain  showed ventriculomegaly, periventricular ischemia, and pseudocysts  in newborns up to one year from mothers with exacerbation of CMV  during pregnancy. Later, minimal brain dysfunctions were manifested by motor disorders, increased general, vegetative excitability, and a  tendency to digestive and sleep disorders. The data obtained  indicate that the exacerbation of CMV infection in the first trimester  of pregnancy is interrelated with a decrease in the concentration of progesterone and its metabolites (5α-dihydroprogesterone, allopregnenolone) in the placenta and development of neurological dysfunction in newborns.
MEDICAL AND SOCIAL CHARACTERISTICS OF WOMEN OF YOUNG REPRODUCTIVE AGE AFTER HYSTERECTOMY
Authors: Frolova N. I. , Belokrinitskaya T. E. , Barkan T. M. , Golygin E. V. , Liga V. F. , Pletneva V. A. , Plotkin I. B. , Potapova E. N. , Tarbaeva D. A. , Khaven T. V. , Falko E. V. , Shemyakina K. N.
Published: September 2018

Background. In many countries, hysterectomy is one of the most frequently performed surgical procedures.

The objective of our analysis was to assess the social and medical characteristics of young reproductive-age patients who underwent hysterectomy.

Materials and methods. A retrospective study involved 140 women aged 18–35 years (median age 29.4 ± 4.7 years) who underwent emergency or elective hysterectomy in the hospitals of Zabaykalsky Krai for a period of 5 years (January 1, 2013, to December 31, 2017).

Results. 51.4 % of patients were housewives; 52.9 % were single; 55.7 % had bad habits (smoking, alcohol consumption). These women had a high incidence of socially significant infections: HIV – 3.6 %, active forms of tuberculosis – 1.5 %. 89.3 % of hysterectomies were emergent and 10.7 % were elective (p = 0.0001; OR = 69.4; 95% CI 32.6–148.1). The indications for the emergency hysterectomy were uterine myoma (80 %) and cervical or ovarian cancer (20 %). The obstetrical complications were the main indications for the emergency surgery: placenta abruption – 24.0 %; placenta previa – 20.8 % (placenta increta and/or percreta – 16.8 %; massive antenatal bleeding – 4.0 %); postpartum hemorrhage after vaginal delivery and caesarean section 19.2 %; septic and/or hemorrhagic shock in early miscarriages (from 8 to 19 weeks of gestation) 15.2 %. Mortality was registered in case of emergency hysterectomy only (4.3 %). Half of the deaths (50 %) occurred in cases of complicated miscarriages.

Conclusion. To preserve the reproductive potential of young women of reproductive age, it is necessary to increase their social and cultural level, and responsibility for their own health and gender behavior.
Conducting Comprehensive Environmental Scans in Health Research: A Process for Assessing the Subject Matter Landscape
Authors: Shahid Maaz , Turin Tanvir C
Published: September 2018

Environmental scans provide researchers with an assessment of the landscape around an issue of interest. In this process relevant information is systematically amassed to identify current status, scopes or opportunities, and risks. This paper aims to serve as a basic and surface level guide to understanding and planning for conducting an environmental scan. The intended audience includes students and researchers new to the use of environmental scans. Before discussion of all the steps, some examples of the use of environmental scans in health research is provided. The process of conducting an environmental scan is outlined in five steps that revolve around purpose, people, questions, information gathering and presenting. The paper concludes with a discussion on advantages and challenges of conducting environmental scans.
BISCUITS SUPPLEMENTARY FEEDING EFFECT ON THE NTRATION OF FERITIN IN PREGNANT WOMEN AT PARBISCUITS SUPPLEMENTARY FEEDING EFFECT ON THE CONCENTRATION OF FERITIN IN PREGNANT WOMEN AT PAREPARE CITYN PRE CITY
Authors: Ryska Hasra , Syam Aminuddin , Leida Ida
Published: September 2018

Supplementary food of pregnant women in the form of layer biscuits made with special formulations and fortified with vitamins and minerals that are known to meet the nutritional needs of pregnant women. This study aims to see the effect of Supplementary Food Feeding biscuits on the concentration of feritin KEK pregnant women in Parepare City 2018. This research is Quantitative Research with Longitudinal approach (Time-Period Approach), the number of samples in this study 42 pregnant women selected by purposive sampling . The data includes the consumption of biscuits obtained from the observation sheet while the ferritin results obtained from the serum taking and the results of the laboratory examination. The result of the research by using logistic regression test showed that there is influence of supplementary food feeding biscuit to ferritin concentration of pregnant women p = 0,024. There was an effect of age on ferritin concentration p = 0,021. Multivariate analysis showed that biscuit consumption had an effect on ferritin concentration (p = 0,024; Exp (B) = 0,636) as well as age correlated with ferritin pregnant women (P = 0,033; Exp (B) = 8,352) and age to the concentration of ferinin pregnant women. Giving PMT can be given to women since pregnancy positive pregnancy and have poor nutritional status. Providing education on good nutrition can be given to pregnant women to increase knowledge and awareness of the importance of good nutrition during pregnancy.
Dilma Rousseff: as eleições e a lógica androcêntrica na política brasileira
Authors: Castro Amanda Motta , Caetano Marcio
Published: September 2018

Com este artigo nos propomos a analisar os modos como as dinâmicas androcêntricas desestabilizam e deslegitimam a presença da mulher no cenário político brasileiro. Para tanto, balizamos nossa análise na emergência eleitoral da candidatura de Dilma Rousseff à presidência da república em 2010. Ao nos centrarmos no percurso eleitoral de Dilma Rousseff, observamos como o trânsito e as participações mantidas pelos diferentes sujeitos na política brasileira assumem configurações diversas, buscando interditar os conhecimentos da mulher e as diferentes formas de entender os espaços e as práticas políticas, afiançando o androcentrismo e a heteronormatividade.
Por dentro do ringue: gênero e sexualidade no embate da inclusão por direitos
Authors: Díaz-Benítez María Elvira , Gonçales Nathalia Ferreira
Published: September 2018

Este ensaio busca refletir sobre os diversos golpes que têm acontecido nas últimas duas décadas em relação às políticas de gênero e sexualidade no Brasil, enfatizando sobre Aborto; o Programa Brasil sem Homofobia; os projetos de “Cura Gay”; a Lei João W. Nery para transexuais; a Lei Gabriela Leite e o embate ao redor da legislação da prostituição; a ideologia de gênero e sua inclusão nos planos curriculares e o Estatuto da família.
Ofis Çalışanlarında Çalışma Postürü, Kas İskelet Sistemi Rahatsızlıkları, Bel Ağrısına Bağlı Özürlülük Düzeyi ve Sağlıkla İlgili Yaşam Kalitesinin İncelenmesi
Authors: KÜÇÜK Fadime , DÜZENLİ ÖZTÜRK Seren , ŞENOL Hande , ÖZKESKİN Mehmet
Published: September 2018

Amaç: Bu çalışmanın
amacı, ofis çalışanlarının çalışma postürü, kas iskelet sistemi
rahatsızlıkları, bel ağrısına bağlı özürlülük düzeyi, sağlıkla ilgili yaşam
kalitesinin incelenmesi, aralarındaki ilişkinin belirlenmesidir. Gereç ve Yöntem: Araştırmaya toplam 213
ofis çalışanı dâhil edildi. Ofis çalışanları, Ovako Çalışma Postürü Analiz
Sistemi, Cornell Kas İskelet Sistemi Rahatsızlığı Anketi, Oswestry Özürlülük
Anketi ve Nottingham Sağlık Profili ile değerlendirildi. Sonuçlar: Oswestry Özürlülük Anketi ile omurga, alt ekstremite, üst
ekstremite ağrı sıklığı,  ağrı şiddeti ve
ağrıya bağlı işin engellenmesi arasında ileri derecede anlamlı ilişkiler
bulundu(p=0,000, r=0,328-0,505). Nottingham Sağlık Profilinin enerji, ağrı,
fiziksel hareketlilik, uyku, emosyonel reaksiyonlar, sosyal izolasyon alt
parametreleri ile omurga, alt ekstremite, üst ekstremite ağrı sıklığı,  ağrı şiddeti, ağrıya bağlı işin engellenmesi
ve bel ağrısı arasında ileri derecede anlamlı ilişkiler bulundu (p=0,020-0,000,
r= 0,159-0,671<0,005). Tartışma:
Kadın ofis çalışanlarının bel ağrısına bağlı özürlülük düzeyi, erkeklerden daha
fazla bulundu. İlişki analizleri incelendiğinde, bel ağrısına bağlı özürlülük
düzeyi ile kas iskelet sistemine bağlı ağrı sıklığı ve şiddeti ile ilişkili
olduğu bu durumun işi engellediği görüldü. Ayrıca bel ağrısına bağlı özürlülük
düzeyi; sağlıkla ilgili yaşam kalitesi ile de ilişkili bulundu. İleride
yapılacak çalışmalarda, ofis çalışanlarının doğru çalışma postürü konusunda
kapsamlı eğitim verilmesi ve yapılacak ergonomik düzenlemelerin sağlıkla ilgili
yaşam kalitesine etkisi üzerine etkisinin araştırılması gereklidir.
LAYANAN BERBASIS LOKASI DALAM SISTEM INFORMASI DAN RUTE RUMAH SAKIT DI KOTA KEDIRI
Authors: Kasih Patmi , Harini Dwi
Published: September 2018

Layanan informasi berbasis lokasi (Location Based Service/ LBS) sudah menjadi suatu kebutuhan yang mengiringi aktivitas masyarakat sehari-hari dalam penyajian informasi yang akurat, khususnya bagi masyarakat yang sangat membutuhkan informasi tertentu dalam kondisi yang mendesak. Demikian juga kebutuhan informasi mengenai rumah sakit dan fasilitas yang disediakan oleh rumah sakit. Sumber informasi tentang rumah sakit sangat diperlukan untuk mengetahui ketersediaan fasilitas di rumah sakit, terutama mengenai dokter ahli dan penyakit yang bisa ditangani. Dalam fungsinya sebagai pendukung layanan GPS (Global Position System) dalam mencari suatu tempat atau lokasi, LBS sangat mendukung fungsi sistem informasi dan rute rumah sakit yang dibangun dalam penelitian ini. Dengan keunggulan dari LBS sebagai gabungan konsep baru Teknologi Informasi dan Komunikasi seperti sistem telekomunikasi selular dan perangkat mobile, dari internet dan dari Sistem Informasi Geografis (GIS) dengan database spasial, diharapkan sistem informasi yang dibangun dapat memberikan manfaat yang maksimal bagi masyarakat. Dalam sistem yang dibangun, informasi tentang rumah sakit yang di berikan meliputi alamat, nomor telepon, e-mail, webside, nama dokter dan penyakit yang ditangani, serta rute menuju rumah sakit.
Genome-Editing and Biomedical Cell Products: Current State, Safety and Efficacy
Authors: Goryaev A. A. , Savkina M. V. , Mefed K. M. , Bondarev V. P. , Merkulov V. A. , Tarasov V. V.
Published: September 2018

Advances in ex vivo technologies of human genome editing have made it possible to develop new approaches to the treatment of genetic, oncological, infectious and other diseases, which may involve the use of biomedical cell products. However, despite the rapid development of these technologies and a large number of clinical trials conducted in many countries around the world, only 4 products (Strimvelis, Zalmoxis, Kymriah and Yescarta) containing ex vivo genetically modified human cells are authorised for use in the European Union and the United States of America. This paper considers three promising technologies (ZFN, TALEN and CRISPR) that allow for easy and effective editing of the genome at the sites of interest, thereby creating a platform for further development of the genetic engineering of human cells. It describes the technology of engineering chimeric antigen receptors (CARs). It also provides data on the efficacy and safety of the approved products: Strimvelis which contains autologous CD34+ cells transduced ex vivo with a retroviral vector containing adenosine deaminase gene, Zalmoxis which contains modified allogeneic T-cells, and two products: Kymriah and Yescarta which contain autologous T-cells with CARs to CD19 antigen, intended for the treatment of CD19+ hematological malignancies.
Microbial Quality of Dehydrated Media Used in the Sterility Testing of Immunobiological Medicinal Products
Authors: Sukhanova S. M. , Zakharova N. E.
Published: September 2018

Medicinal products fail sterility testing if visual observation shows the growth of microorganisms that manifests itself as turbidity, sedimentation, flocculation and other changes in the growth medium. A key factor allowing robust determination of changes in the culture that may be suspected of contamination is the quality of growth media used, namely their transparency, and absence of foreign matter detectable by microscopic examination of the growth media smears. The presence of such foreign matter makes it especially difficult to interpret the results of testing of immunobiological products, namely live bacterial vaccines, because they cause turbidity of the media due to their specific composition. The article dwells upon the results of testing (in terms of Transparency and Microbial content) of dehydrated growth media recommended by the State Pharmacopoeia of the Russian Federation, 13th ed., General monograph 1.2.4.0003.15 for sterility testing of immunobiological medicinal products. The study revealed the presence of microorganisms, including pathogenic ones, in the growth media. In view of the fact that certificates of analysis and technical documentation accompanying components of growth media and dehydrated growth media produced by most national and foreign manufacturers do not contain any data on the acceptable levels of microorganisms it is argued that these products have to be tested for microbial content. The study also investigated the ways of improving the quality of commercial dehydrated growth media at the preparation stage.
A Numerical Study on the Effects of Exhaust Gas Recirculation Temperature on Controlling Combustion and Emissions of a Diesel Engine running on HCCI Combustion Mode
Authors: RATHER Mushtaq Ahmad , WANİ Mohammad Marouf
Published: September 2018

In this study a
comprehensive study is carried out numerically on a single cylinder four-stroke
Diesel engine operating in homogenous charge compression ignition (HCCI) mode
of combustion for the effects of exhaust gas recirculation (EGR) temperature
and percentage on the combustion and emission characteristics. An advanced
version of ANSYS IC Engine FORTE coupled with highly efficient and detailed
pre-defined industry standard chemical kinetics CHEMKIN is used to solve the
chemical reaction mechanism and species thermodynamic data. The analysis was
carried out at three different EGR temperatures of 363K, 404K and 513K for 10%,
20% , 30%, 40% and 50% EGR each. The results predicted that the combustion
ignition timing is advanced by increasing the EGR temperature. The effect of
low EGR temperature is predominant at higher percentages of EGR. It was also
found that the CO and UHC levels nearly kept constant with an increase in EGR
temperature the NOx levels increase linearly with an increase in EGR
temperature. The HCCI combustion in diesel engine can be controlled by
adjusting the temperature and mass percentage of exhaust gas recirculation
while retaining lower NOx emissions and very little increase in CO and unburnt
hydrocarbons.
Primera descripción de Argenteohyla siemersi pederseni (Amphibia, Anura, Hylidae) y comentarios sobre su estado taxonómico
Authors: Zaracho Victor Hugo , Areta Juan Ignacio
Published: September 2018

Actualmente se reconocen dos subespecies de Argenteohyla siemersi, la nominal A. s. siemersi y A. s. pederseni. Se ha sugerido que estudios cromosómicos y bioacusticos podrfan ayudar a clarificar su estado taxon6mico. En este trabajo describimos por primera vez el canto de advertencia de Argenteohyla sieniersi pederseni sobre la base de una poblaci6n procedente de la Reserva Natural Provincial Ibera, cerca de la localidad de Colonia Carlos Pellegrini, Corrientes, Argentina. El canto de A. s. pederseni es muy variable en duraci6n y numero de notas. Ademas, parecen vocalizar en duos sincronizados evitando la superposici6n de notas. En comparaci6n con la subespecie nominal, existen diferencias con respecto a la frecuencia fundainental y al número de notas por canto, siendo mayor en A. s. pederseni queen A. s. siemersi. Estos datos sugieren que siemersi y pederseni podrfan corresponder a dos especies biol6gicas distintas, pero más trabajo es necesario para corroborar esta propuesta.
IMPEMENTASI RANTAI PASOK HIJAU PADA MATERIAL PROYEK DALAM MENDUKUNG KONSTRUKSI BERKELANJUTAN
Authors: Putri Offie Nurtresnaning
Published: September 2018

Industri konstruksi khususnya di Indonesia termasuk dalam kategori sebagai negara yang responsive terhadap penyelenggaraan konstruksi di dunia. Dengan dimulainya era green construction, fokus penyelenggaraan infrastruktur dewasa ini tidak saja hanya memfokuskan perhatiannya pada aspek sosial dan ekonomi, namun juga aspek lingkungan hidup.
MENJAMIN KUALITAS VAKSIN DENGAN MANAJEMEN RANTAI DINGIN
Authors: Warihwati Rinansita
Published: September 2018

Kemajuan Konsep paradigma sehat di dalam pembangunan kesehatan adalah pembangunan kesehatan yang lebih memprioritaskan upaya promotif dan preventif dibandingkan kuratif dan rehabilitatif. Program imunisasi merupakan salah satu upayapreventif yang telah terbukti sangat efektif menurunkan angka kesakitan dan angka kematian serta kecacatan pada bayi dan balita (Ditjen Bina Kefarmasian dan Alat Kesehatan Depkes RI, 2009).

Vaksin merupakan komponen utama dalam program imunisasi dimana ketersediaannya harus terjamin sampai ke sasaran. Sesuai dengan PP 38 tahun 2007 tetang kewenangan pemerintah dan kewenangan provinsi sebagai daerah otonomi dan Peraturan Menteri Kesehatan No. 439/ MENKES/ PER/ VI/ 2009 tentang Perubahan Kedua Atas Peraturan Menteri Kesehatan No. 1575/ MENKES/PER/XI/2005 tentang Organisasi dan Tata Kerja Depkes, antara lain menyebutkan bahwa kewenangan pemerintah pusat menyediakan obat esensial tertentu dan obat sangat esensial untuk pelayanan kesehatan dasar. Selain itu pemerintah juga menjamin ketersediaan bahan imunisasi yang aman, bermutu, efektif, terjangkau, dan merata bagi masyarakat untuk upaya pengendalian penyakit menular melalui imunisasi (Undang - Undang Kesehatan RI No. 36/09).

Sejak ditemukannya vaksin dan tehnik pembuatan vaksin yang semakin berkembang pesat hingga saat ini, ada satu hal yang mutlak harus ada bila kita berbicara tentang penyimpanan vaksin, yaitu rantai dingin atau cold chain, yaitu suatu sistim penyimpanan vaksin dengan suhu antara 2 – 8 derajat Celsius, agar supaya komponen dalam vaksin yang bersifat bioaktif tidak mengalami kerusakan karena suhu yang tinggi atau suhu yang terlalu rendah, sehingga dengan suhu penyimpanan yang tepat, potensi proteksi vaksin akan tetap terjaga maksimal hingga waktu yang telah ditentukan oleh pabrik pembuat vaksin, yang ditentukan dengan yang disebut Expiration Date atau Waktu Kadaluarsa vaksin.
ANALISIS METODE VARIABLE COSTING UNTUK PERENCANAAN LABA
Authors: ATHORI AGUS
Published: September 2018

PT Sumber Rejo Kandangan adalah perusahaan yang bergerak di bidang industri tepung tapioka. Selama ini PT Sumber Rejo dalam merencanakan labanya belum menggunakan analisis variable costing sehingga perencanaan yang dilakukan jarang bisa terpenuhi. Tujuan dalam penelitian ini adalah mengetahui penggunaan metode variable costing dapat digunakan sebagai alat untuk perencanaan laba bagi PT Sumber Rejo, Kandangan.Jenis Penelitian yang peneliti gunakan dalam penyusunan penelitian ini adalah jenis penelitian deskriptif. Variabel yang diteliti adalah metode variable costing dan perencanaan laba. Analisa data secara kuantitatif dengan menggunakan analisis deskriptif.Selama ini PT. Sumber Rejo menggunakan perhitungan laba rugi menggunakan full costing sehingga kesulitan dalam melakukan perencanaan produksi tahun berikutnya, hal ini menyebabkan perusahaan dalam menentukan perencanaan laba tidak seimbang dengan penentuan target produksi, akibatnya sering kali perencanaan laba tidak terpenuhi akibat dari target produksi yang tidak sesuai, dengan menggunakan variabel costing akan mempermudah proses perencanaan laba yang dapat disesuaikan dengan kapasitas produksi pertahunnya sehingga perencanaan laba yang dibuat lebih nyata karena hanya memperhitungkan biaya-biaya variabel dalam perhitungan biaya produksi. Berdasarkan perencanaan laba yang ditetapkan oleh pihak PT. Sumber Rejo pada tahun 2015 adalah Rp. 1.400.000.000 maka jumlah penjualan yang diperlukan untuk mencapai target laba tersebut Rp. 11.183.564.933 atau 7.498 ton produk. Penggunaan variabel costing dalam perencanaan laba yang dilakukan dapat disertai dengan penganggaran biaya secara tepat karena perhitungan biaya berdasarkan jumlah rencana produksi.PT. Sumber Rejo diharapkan dapat menerapkan proses pelaporan laba rugi dengan menggunakan metode direct costing dengan mempertimbangkan pemisahan antara biaya tetap dengan biaya variabel sehingga akan lebih mudah dalam menentukan penentuan perencanaan laba, penjualan dan produksi.Kata Kunci : Perencanaan Laba, Variable Costing
IMPLEMENT APPLICATION OF TAGUCHI METHOD FOR ANALYZING THE QUALITY CONTROL OF CRUDE PALM OIL PRODUCTION
Authors: Aryza Solly , Lubis Andre Hasudungan , Sutrisno Sutrisno
Published: September 2018

A quality control towards the production of Crude Palm Oil (CPO) production is a prominent instanceto be held by companies. Through Taguchi method, several steps are conducted start with the selection of factorsthat affect the quality of CPO and factor level values which then become the basis in the selection of orthogonalmatrices. Based on the result of the research, it is found that the factors that significantly influence the quality ofCPO are boiling pressure, boiling temperature and clarification unit temperature. After applying the optimalcombination of settings based on the Taguchi method, the overall proportion of overall defects decreased by10.42%.Keywords: CP
KEPUTUSAN PENETAPAN HARGA JUAL UNTUK PESANAN KHUSUS
Authors: ATHORI AGUS
Published: September 2018

Perusahaan Roti Lezzat Jombang adalah pabrik yang bergerak dalam bidang makanan yang berupa roti. Dengan semakin bertumbuh dan berkembangnya ekonomi yang ada di wilayah Jombang, menuntut pabrik untuk memperoleh keuntungan yang sebesar-besarnya atau dengan kata lain laba yang maksimal. Penetapan harga jual yang sangat rendah tidak akan memberikan keuntungan atau laba bagi perusahaan, sedangkan penetapan harga jual terlalu tinggi juga akan berdampak pada produk yang dihasilkan kurang bersaing di pasar.Tujuan penelitian ini di buat yaitu untuk mengetahui bagaimana Perusahaan Roti Lezzat menetapkan harga jual sesuai dengan menggunakan harga jual menurut metode harga biaya plus. Dari hasil survey, metode yang cocok untuk digunakan adalah metode deskriptif kuantitatif. Dari hasil penelitian, Perusahaan Roti Lezzat Jombang belum menerapkan analisis harga biaya plus dalam menghitung harga untuk pesanan khusus. Dari hasil penelitian, dalam penetapan harga jual dengan menggunakan metode ini menunjukkan hasil yang lebih rendah dibanding dengan menggunakan metode yang digunakan perusahaan Roti Lezzat Jombang sebelumnya. Perusahaan Roti Lezzat Jombang sebaiknya menggunakan dan menerapkan metode harga biaya plus dengan pendekatan biaya variable dalam menghitung harga jual sehingga harga jual yang diharapkan oleh perusahaan Roti Lezzat Jombang lebih dapat bersaing dengan produk yang sama atau sejenis yang ada di pasar.Kata Kunci : harga biaya plus, biaya variable, harga jual, pesanan khusus.
KAJIAN KOMPARATIF PENGEMBANGAN EKOWISATA BAHARI VERSUS PENANGKAPAN IKAN DI PERAIRAN PULAU KOON - MALUKU
Authors: Sutiarso Moh Agus
Published: September 2018

This research was conducted in the district of Pulau Gorom, East Seram Regency, Maluku, in the context of developing marine ecotourism in the Koon Island Ocean. Data collection is done using interview and literature study methods. The analysis technique uses benefit-cost ratio analysis, in addition to using qualitative analysis techniques. From the analysis results show that the Koon Island Ocean deserve to be developed into marine ecotourism, because the benefit-cost ratio is two times greater than the benefit-cost ratio for traditional fishing. The tourism sector has advantages with other sectors mainly in the form of labor intensive and tourism sector margins far higher than other economic sectors.
Peran Humas Kota Padang dalam Mensosialisasikan Smart City di Kota Padang
Authors: Darman Ridho
Published: September 2018

Konsep smart city kini tengah marak digalakkan di berbagai negara, termasuk Indonesia. Penerapannya pun dinilai sangat bermanfaat bagi kehidupan masyarakat. Kota Padang merupakan pusat pendidikan di Sumatera Barat, dimana pendidikan merupakan salah satu faktor terpenting di dalam mewujudkan smart city. Penelitian ini bertujuan untuk mengetahui sejauh mana peran Humas Kota Padang dalam mensosialisasikan smart city di Kota Padang.
A NEW CASES EXISTENCE OF LEGAL FICTION PRINCIPLES INDONESIA LAW
Authors: Aryza Solly
Published: September 2018

The principle of Fixie Rechts or Legal Fiction still embraced in Indonesian legislation. It does notmatter that the policy is inconsistent with reality on the ground, which in fact creates more and more newproblems. For example the application of laws in very remote areas. How can a rural person who has no accessto information, if he does not comply with a rule that has been passed by the state through the state gazette, thenwithout considering the absorption aspect of his information, he remains entangled in the law. Because he afterthe law was enacted, he was supposed to know the law. This study uses normative legal research method byreviewing the literature related to legal fiction. Surely the principle that is deemed irrelevant to its real conditionlike this deserves no longer applied. For that required seriousness of government and society in participatingeliminate this law fiction principle. The results of this research show that Indonesia still enacts law governmentand culture as well, law maker or legislator and organization publish that.
A Home for Faculty in the Library: Digital Publishing and Exercises in Innovation from Harvard Law School
Authors: Courtney Kyle K. , DeMarco Claire
Published: September 2018

As libraries continue transforming through the digital age, we are faced with a familiar opportunity for renewal: the deepening of the faculty-library relationship -- this time in a digital framework. Instead of simply complementing analog disciplines with digital counterparts, a broader medium of “digital scholarship” is rapidly expanding among and across all disciplines. Like any rapid expansion, there is no one clear path. Hundreds of platforms are vying for prominence in the digital scholarship space; commercial publishers are developing, enhancing, and re-branding online portals to meet this demand. Rather than coping with that uncertainty, however, or formatting their work to fit a standard, commercial digital mold, many faculty are turning to trusted sources: librarians. Faculty are seeking guidance, support, and resources to meet their digital scholarship needs, meaning libraries are presently in a position to become the place where -- and the partner through which -- faculty create, manage, and store digital scholarship placing libraries in the position of digital publisher. In recent years, commercial publishers have positioned themselves to transition traditional print journals and monographs to e-publishing platforms aimed at merely replicating the print experience. Ongoing management of those platforms, along with development of licensing and payment structures, have likewise attempted to replicate the print experience. Debate has surrounded library ownership of electronic resources, and the divorce of licensed content from traditional modes of print ownership has been, and continues to be, an area bereft of clarity and mired in controversy. This current opportunity is more than a mere transition, however, it is an expansion – a broadening of our understanding of scholarship, not to simply replace print with digital, but to encourage and understand the opportunities of the digital environment as a new medium for faculty. As we face this evolution from replicating print in a digital environment, to authoring and creating within a digital framework, libraries must be assertive in taking on the challenges of developing a home for this content and become comfortable with digital publishing as a core library function.This article highlights specific examples of desire by faculty at Harvard Law School to push legal scholarship beyond the constraints of traditional commercial publishing. Analysis of these examples will focus on the unique role that the library has in stimulating, supporting, and sustaining, faculty publishing efforts, in addition to the challenges presented by the new, and potentially uncomfortable, proposition of library as a digital publisher.
Clarifying the Effect of Test Speededness
Authors: Hong Maxwell , Cheng Alison
Published: September 2018

In the context of high-stakes tests, test takers who do not have enough time to complete a test rush towards the end and may engage in speeded behavior when tests do not penalize guessing. Using mathematical derivations and simulations, Attali (2005) showed that random guessing responses should attenuate inter-item correlations, and therefore decrease estimates of reliability. Meanwhile, Wise and DeMars (2009) showed that random guessing could in fact inflate reliability estimates using real data. We provide analytical derivations on how speededness could affect correlations between two dichotomous items in multiple ways, depending on the manifestation and prevalence of test speededness. Furthermore, we provide two simulation studies that evaluate the magnitude of impact of test speededness on inter-item correlations and Cronbach's Alpha. We found that the impact of test speededness can vary between item pairs and that it depends on the manifestation of test speededness and item level characteristics. Furthermore, speeded responses will, in general, attenuate or not affect reliability estimates, depending on the prevalence of such responses and conceptual interpretation of speeded responses. Implications of the findings are discussed.
Alternative causal explanations for order break the link between order and agents
Authors: Schachner Adena , Kim Minju
Published: September 2018

People often believe that orderly structures were created by agents. We examine the cognitive basis of this tendency, and its malleability, focusing on orderly musical sounds as a case of interest. If simple associations mediate the link between order and agents, then detection of orderly stimuli should lead people to infer the presence of agents, independent of other factors. If causal reasoning mediates the link, then an alternative physical explanation for order should explain away its link with agents. We presented participants with orderly or disorderly outcomes in the form of musical sound sequences, and manipulated whether there was an alternative physical explanation for each outcome. Participants saw a scene involving a staircase-like xylophone, where a ball rolling downhill would produce an orderly descending scale. This provided an alternative physical explanation for how this orderly outcome could be generated. We found that when this scene was shown, then occluded, people did not infer the presence of an agent after hearing the orderly descending scale. In contrast, people expected an agent after hearing a scrambled sequence of tones, which could not be produced by gravity in this context (Exp. 1). When we subtly changed the scene by shuffling the xylophone’s bars, so gravity would not create an orderly outcome, participants readily inferred the presence of an agent from the same orderly stimulus. When we controlled for the presence of an alternative explanation, and manipulated orderliness, orderliness had no effect (Exp. 2). Across both experiments, alternative causal explanations flipped participants’ judgments such that disorder, and not order, led people to infer the presence of an agent. These findings show that the link between order and agents is mediated by causal reasoning, and can be weakened by understanding an alternative mechanism by which order could arise.
Problematic low power in many Psychonomic Society journal articles
Authors: Morris Peter E. , Fritz Catherine O.
Published: September 2018

Low power, often the result of an insufficient number of participants, contributes to replication failures (e.g. Button et al., 2013). It is usually recommended that studies have at least an 80% chance of identifying an effect. However, following Cohen’s (1962) work, many reviews have reported that studies are under-powered. We calculated the power to detect small, medium and large effects of a test from the first study in all relevant Psychonomic Society journal articles published in 2017. Overall, mean power to detect medium sized effects was only 65%, and two-thirds of papers failed to achieve 80% power. Nearly half of papers in Psychonomic Bulletin & Review and Memory & Cognition achieved the 80% criteria, but other journals were much lower. The mean power to detect small effects was 22%, indicating that they would almost always be missed. Larger samples are generally needed to avoiding missing real effects.