bluuebunny/crossref_metadata_2025 huggingface dataset:
The Journal “Engines Construction”: over 40 Jears the Frontier of Engine Building Science
Authors:   LLC “NPF “Ecology”, Novikov L.A. , Chaynov N.D. ,   Bauman Moscow State Technical University (BMSTU), Markov V.A. ,   Bauman Moscow State Technical University (BMSTU)
Published: November 2022

The article presents the materials about the history of the creation and publishing activities of the journal “Engines Construction”, first in Leningrad (at the Central Research Diesel Institute — TSNIDI), then in St. Petersburg (at LLC «TSNIDI-Ecoservice»). Also, the article elaborates on the reasons for the transfer of the rights of the founder and publisher to the Bauman Moscow State Technical University. We show the main stages of the formation of the “Engines Construction”, journal as the leading scientific and engineering publication in the field of development of Russian marine, diesel, automotive and industrial engines are. The article talks about prominent scientists who collaborated with the editorial board and published in the journal. We give the journal scope within the framework of which scientific and technical articles are published on various topics of developing and improving engines for various purposes. Lastly, we present new scientific specialties for which the journal is being re-registered in the list of the Higher Attestation Commission (VAK) of the Russian Federation.
Butler’s “Future State” & Hume’s “Guide of Life”
Authors: Russell Paul
Published: November 2022

In this paper I argue that Hume’s famous discussion of probability and  induction, as originally presented in the Treatise, is significantly motivated by irreligious objectives. A particular target of Hume’s arguments is Joseph Butler’s Analogy of Religion. In the Analogy Butler intends to persuade his readers of both the credibility and practical importance of the doctrine of a future state of rewards and punishments. The argument that he advances relies on probable reasoning and proceeds on the assumption that our past experience in this life serves as a reliable and effective guide for our expectations concerning a future state. In the relevant sections of the Treatise Hume aims to discredit this religious argument and the practical objectives associated with it.
Artificial Intelligence: Use in Clinical and Genomic Diagnostics
Authors:   Hiralal Mazumdar Memorial College for Women, Dakshineswar, Kolkata, West Bengal, Ahmad S Rehan
Published: November 2022

The development of computer systems that are capable of carrying out tasks that typically require human intelligence is known as artificial intelligence (AI). Recent and quickly rising interest in medical AI applications is a result of AI software and technology improvements, especially deep learning algorithms and the graphics processing units (GPUs) that enable their training. While other AI subtypes have started to show similar promise in different diagnostic modalities, AI-based computer vision methods are poised to change image-based diagnostics in clinical diagnostics. Large and complicated genomic datasets are processed using a particular form of AI algorithm known as deep learning in various fields, such as clinical genomics. In this review, we first provide an overview of the primary categories of issues that AI systems are best adapted to address, followed by a description of the clinical diagnostic tasks that are aided by these solutions. Then, we concentrate on recently developed techniques for certain clinical genomics applications, such as variant calling, genome annotation and variant categorization, and phenotype-to-genotype correlation. We conclude by talking about the future potential of AI in individualized medicine applications, particularly for risk prediction in common complex diseases, as well as the issues, constraints, and biases that must be carefully addressed for the successful deployment of AI in medical applications, particularly those using data from genomics and human genetics.
Las limitaciones de la tipificación de infracciones en materia de fauna silvestre, a propósito del procedimiento administrativo sancionador iniciado contra la refinería La Pampilla
Authors: García Cerrón Erick Leddy
Published: November 2022

El derrame de hidrocarburos en el mar de Ventanilla ha supuesto un gran reto para las entidades públicas responsables de manejar este desastre ambiental. A ello se suman distintas voces desde la opinión pública que exigen que la refinería La Pampilla, propiedad de la empresa Repsol, asuma su responsabilidad, entre otros aspectos, por la grave afectación causada a la fauna silvestre. En este contexto, el Servicio Nacional Forestal y de Fauna Silvestre, a través de la Administración Técnica Forestal y Fauna Silvestre Lima, inició un procedimiento administrativo sancionador contra la citada empresa imputándoles, como conducta infractora, actuar con crueldad y causar la muerte de especímenes de la fauna silvestre marina. Sin embargo, esta acción, que podría considerarse como una medida indispensable para alcanzar justicia ante el grave daño ocasionado contra nuestros recursos naturales, podría terminar convirtiéndose en un serio revés en esta búsqueda estatal de justicia ambiental. Del análisis del principio de tipicidad que regula el ejercicio de la potestad sancionadora administrativa y la legislación sobre fauna silvestre, se verifica que nuestro ordenamiento jurídico no ha incorporado disposiciones legales que permitan sancionar por el agravio originado a la fauna silvestre producto del derrame de hidrocarburos. Estas inconsistencias se evidencian en el proceso para delimitar con precisión la conducta infractora, la cual, al presentar vacíos a nivel de la norma sustantiva, termina proyectando un escenario desfavorable para declarar la responsabilidad administrativa e imponer la sanción correspondiente por los hechos cometidos.
Impact des Déchets Plastiques sur les Pâturages Urbains et Péri-urbains de la Ville de Dori, Région du Sahel : cas des Ruminants Domestiques
Authors: Ouédraogo Aïcha , Akoudjin Massouroudini , Somda Martin Bienvenu , Comboigo Sidpakissidé Marius , Karambiri Sheila Médina , Boma Soudah , Soha Sesseya Arnaud Sas , Belem Marie Gaston Adrien , Sawadogo Rassablaga Dominique
Published: November 2022

Les pâturages naturels constituent la principale ressource alimentaire des ruminants dans la zone urbaine et péri-urbaine de Dori. Ces pâturages naturels sont non seulement insuffisants pour les animaux mais aussi pollués par les sachets plastiques. Cette insuffisance alimentaire (quantitative et qualitative) amène les ruminants à ingérer des sachets plastiques. Notre étude avait pour objectif général d’étudier la prévalence de l’ingestion des sachets plastiques chez les ruminants (bovins, caprins et ovins). Elle s’est déroulée de février à juin 2021 par une collecte aléatoire de données à l’abattoir sur 600 échantillons de ruminants domestiques : 200 bovins, 200 caprins et 200 ovins. Nos résultats ont révélé que la prévalence de l’ingestion des sachets n’est pas liée à l’espèce: 31,5% chez les ovins, 30% chez les bovins et 23% chez les caprins (p = 0,131). Cette prévalence n’est pas également liée au sexe: 30% chez les femelles contre 26% chez les mâles (p = 0,379). Par ailleurs, les poids des sachets ingérés variaient significativement d’une espèce à l’autre (p < 0,001). Ainsi les bovins et ovins avaient tendance à en consommer plus que les caprins (p < 0,05). Les poids vifs et carcasses des animaux ayant ingérés des sachets plastiques sont sensiblement égaux à ceux qui n’en ont pas ingérés. Notre étude suggère que des dispositions particulières soient prises, notamment l’élevage en stabulation et la sensibilisation à l’usage et gestion des sachets dans les villes.
Les Niayes du Littoral Nord du Senegal: Processus de Mise en Place, Salinisation des eaux Souterranies et des Sols
Authors: Fall Marième , Niang Souleymane , Sy Boubou Aldiouma
Published: November 2022

L’espace couvert par les Niayes fait partie des secteurs les plus fertiles du pays. Il subit actuellement un processus de dégradation des systèmes de production dont la salinisation de la nappe constitue le facteur dominant. L’objet de cette contribution est d’analyser la salinisation des eaux souterraines et des sols dans les Niayes et particulièrement dans les différents sites d’étude notamment le lac Wouye, le lac Tanma, les villages de Taré et de Darou Mboumbaye. La méthodologie déployée est essentiellement basée sur le prélèvement et l’analyse au laboratoire. Elle a permis de mesurer la salinité des sols et des eaux souterraines de la nappe des sables quaternaires en 2010 et 2018. Ainsi, les résultats démontrent une dégradation progressive des eaux d’irrigation et une faible salinité dans le complexe absorbant. Par conséquent, la quasi-totalité des terres est abandonnée dans les sites étudiés à cause de l’alcalinisation mais surtout la salinisation des eaux souterraines qui constitue la principale source d’irrigation. Ainsi, un nombre important de maraîchers a perdu une bonne partie des terres agricoles : lac Wouye (60 %), lac Tanma (50 %), Taré (40 %), Darou Mboumbaye (80 %). Si les modifications du lac Wouye et Tanma ont entrainé la perte progressive de leur valeur naturelle et des activités maraichères, les sites de Taré et de Darou Mboumbaye sont, en revanche, menacés par la migration vers le sud de la brèche ouverte sur la Langue de Barbarie. Dans ce contexte, la maitrise des modifications environnementales et de l’irrigation constitue les premiers facteurs d’amélioration de la production maraichère.
Caractéristiques de la Dynamique des Oiseaux d’Eau sur le Bras Majeur de la Komadougou-Yobé dans les Communes de Diffa et Gueskerou, Niger
Authors: Youssoufa Issiaka , Kaoulé Karema Ary Madou , Toudjani Assane Anabi , Moustapha Grema , Ali Mahamane
Published: November 2022

Cette étude à pour objectif de caractériser la faune aviaire sur un transon de 10 km de la Komadougou en période hivernale dans les communes de Diffa et Gueskerou. Les oiseaux ont été dénombrés entre juillet et octobre 2021 suivant des lignes transects avec des points d’arrêt de 20 minutes par endroits. Un total de 25 espèces appartenant à 12 familles et 8 ordres ont été identifiées. La présente étude révèle la présence d’une nouvelle espèce jamais observée dans cette localité. Il s’agit de Platalea alba. La communauté ornithologique est dominée par les espèces telles que Dendrocygna viduata, Plegadis falcinellis , Egretta garzetta, Actophilornis africana et Egretta intermedia. Au plan biogéographique, 10 espèces sont résidentes, une espèce migratrice intra-africain, trois sont migratrice du paléarctique. Six (6) espèces sont résidentes et migratrices intra-africaines, une espèce est résidente, migratrice intra-africaine et migratrice du paléarctique et une espèce rare. Cette étude, la première du genre dans cette zone, constitue une base de donnée sur l’avifaune de la rivière komadougou, ainsi que son importance quantitative et qualitative.
Dynamique de la Macrofaune des Bas-fonds Soundano – saheliens dans un Contexte de Changement Climatique: Étude de cas dans le Sous-bassin Versant du Nakanbé-Dem au Centre-nord du Burkina
Authors: Ilboudo Adama , Traore Mamoudou , Hien Edmond , Prosper Zombre
Published: November 2022

La dégradation des bassins versants est une preuve du changement environnemental que connait l’Afrique de l’ouest. Elle s‘exprime par la dégradation des sols de bas-fonds qui demeure une préoccupation récurrente dans les pays sahéliens comme le Burkina Faso. Cette étude analyse la dynamique de la macrofaune des sols de bas-fonds et a pour objectif principal de contribuer à la gestion durable des bas-fonds de la zone soudano-sahélienne. De façon spécifique, il s’est agi de (i) évaluer la richesse spécifique de la macrofaune des sols de bas-fonds, (ii) déterminer la composition de cette macrofaune et (iii) analyser sa distribution selon les sous unités géomorphologiques des bas-fonds et la profondeur du sol. L’étude a été conduite dans le sous-bassin versant du Nakanbé-Dem au Centre-nord du Burkina Faso. Un échantillonnage spatialisé de la macrofaune du sol par la méthode TSBF a été réalisé pour analyser les principaux facteurs explicatifs de la variabilité spatiale de la macrofaune dans les bas-fonds. La fertilité chimique des sols de bas-fonds en milieu plutonique est faible par rapport au degré moyen de la fertilité des sols de bas-fonds en milieu de l’ensemble volcano sédimentaire. L’évaluation de la macrofaune du sol a révélé que les indices de diversité les plus élevés ne dépassent guère 2,40 ± 0,09 pour Shannon et 1,09± 0,02 pour Piélou. La plus grande proportion de la macrofaune est relevée dans les profondeurs de plus de 20 cm du sol. L’étude a relevé un état dégradé des bas-fonds dont les sols sont de fertilité basse à moyenne. La restauration des écosystèmes de ces bas-fonds nécessite une correction des éléments déficitaires si l’on veut gérer durablement les sols de ces bas-fonds.
Fostering Active Learning in an International Joint Classroom: A Case Study
Authors: Griebel Stefanie , Thielsch Angelika , Gibson Paul , Reiffenrath Tanja , Beissinger Timothy , Chiteka Albert
Published: November 2022

Engaging students in an international online setting that is interdisciplinary and culturally diverse is a challenge. A joint classroom between German and Ugandan universities used a formative assessment approach paired with active learning elements to foster individual and peer learning in an international virtual setting. A survey at three different times across the semester explored students’ perceptions towards the value of the active learning activities and evaluated how perceptions changed over time. Overall, students enjoyed the diverse active learning activities and perceived value toward their success in class. This was more pronounced and unidirectional for individual tasks than it was for group work. In addition to the findings of the structured survey, observation and feedback indicated that other elements contributed to effective course delivery. These included clear and frequent communication to the students from the primary instructor, prompt feedback from the instructor on graded exercises, such as a reflective learning diary and ungraded quizzes, and student confidence that sincere effort would achieve a good grade.
FOOD ENVIRONMENT OF JUNIOR HIGH SCHOOLS IN TOMOHON CITY, INDONESIA
Authors: Octawijaya Ishak Halim , Wariki Windy Mariane Virenia , Hori Ai , Ichikawa Masao
Published: November 2022

Introduction: In Indonesia, child obesity is increasing, and children take a substantial amount of daily calorie from food consumption at school. Methods: This paper describes school food environment in Tomohon City, North Sulawesi Province. We conducted on-site observation and interview with food vendors at 20 junior high schools, describing the food environment by availability and sales of foods and beverages at schools in urban and rural areas. Rice or noodle meals and deep-fried snacks were sold in all schools. Result: The availability and sales of industrial sweets and sugar-sweetened beverages were greater in urban than rural areas, whereas those of fruits were greater in rural areas. Oily and sugary foods and beverages are widely available and consumed by students at schools in the city of Indonesia. Conclusion: Such school food environments and dietary habits should be improved in the effort of halting the increasing prevalence of child obesity.
Pengetahuan Masyarakat Mengenai Penyakit Kecacingan di Desa Sungai Madang Kecamatan Sungai Tabuk Kab Banjar Kalimantan Selatan
Authors: Isnaini Isnaini , Hayatie Lisda , Emelda Zulfa
Published: November 2022

Sungai Madang Village is a village located on the banks of the Tabuk river. This village is located in Sungai Tabuk District, Banjar Regency, South Kalimantan. The location of the village which is on the edge of the river and the many tributaries that surround the village of Sungai Madang make this village at risk of worm disease. This study aims to determine the level of public knowledge of helminthiasis and the use of worm medicine. The method used is the interview technique. The data obtained will be described. The profile of respondents as much as 31.25% are early elderly, 81.25% are women and 93.75% are married. The results of the survey show that 75% of respondents do not know about helminthiasis and they cannot mention the characteristics of helminthiasis. Profile of respondents who know about helminthiasis and they can mention the characteristics of helminthiasis 90.91% Women, 45.45% early elderly and 100% married. The number of respondents who have never used deworming medication is the same as the number of respondents who have used deworming medication, which is 46.9%. Meanwhile, the profile of respondents who have used deworming medication 93.33% are married, 80% are women, 40% are early adults. The conclusion is the community in Sungai Madang Village still have low knowledge about helminthiasis and the use of worm medicine.Keywords: knowledge level, helminthiasis, Sungai Madang, worm medicine
Pelatihan Produksi Sabun Cair dari Crude Palm Oil (CPO) di Desa Jilatan Kabupaten Tanah Laut Dalam Rangka Pencegahan Covid 19
Authors: Susi Susi , Akbar Arief Rahmad Maulana , Hustiany Rini , Millati Tanwirul , Wibowo Alan Dwi , Maharani Dessy Maulidya , Legowo Agung Cahyo
Published: November 2022

Prevention of the COVID-19 virus can be done by regularly washing hands or using hand sanitizer. This step can prevent the COVID-19 virus from sticking to the surface of the skin.. Therefore, the availability of hand washing soap is urgent as an initial step for corona prevention. The availability of hand soap can be provided independently in the community because the liquid laundry soap can be processed with palm oil. It can be an opportunity for the palm oil community to produce and fulfill the needs community. Handling problems by the community in the era of the covid 19 pandemic are related to understanding and insight for preventing Covid 19 from the family environment, one of which is the awareness of washing hands as often as possible using soap. Therefore, knowledge of producing crude palm oil-based liquid soap in communities around oil palm plantations as well as knowledge of the role of palm-based liquid soap for sanitation and entrepreneurial opportunities are good. This community service activity was conducted through counseling and training related to the manufacture of crude palm oil-based liquid soap for the community of oil palm farmers around the Cipta Prima Sejahtera Professional Services Cooperative in Jilatan Village, Tanah Laut Regency. The activity was to provide knowledge about palm oil and liquid soap-based palm oil that are easy to prepare. During the Covid 19 period, hand washing activities are important as a preventive measure, so the availability of liquid soap independently needs to be produced. The evaluation showed that the training participants were very satisfied with this training, gave a very good response regarding the usefulness and sustainability of this community service activity, and hoped that it could be followed up regarding business sustainability.
Perancangan Tourism Display Board untuk Objek Wisata Pasar Terapung Lok Baintan
Authors: Hastuti Karunia Puji , Aristin Nevy Farista , Saputra Aswin Nur , Setiawan Faisal Arif
Published: November 2022

AbstractLok Baintan Floating Market is a leading tourist attraction on a national scale. Completeness of facilities is the main requirement as a support for tourist attractions. The existence of a tourism display that contains information on tourist destinations is very important for tourists. The purpose of the service activity is to provide knowledge about the management of tourism places through the design of information boards Tourism displays provide the information tourists need in tourist attractions. Tourism displays can be information about tourist attractions, such as geographical conditions, history, prices, prohibitions, and warnings in tourist attractions. The limited availability of tourism displays in tourist attractions is caused by several things such as immature planning of tourist attraction, the results of needs analysis that have not listed them, and minimal knowledge of making information boards. The design of tourist information boards is a solution to introduce the culture of tourism promotion. The results of the service showed that 96% of the community felt very satisfied. The design of information boards can be a mobilizer for local people to increase knowledge related to tourism promotion. Keywords: tourism, tourist attractions, tourism display board AbstrakPasar Terapung Lok Baintan merupakan atraksi wisata unggulan berskala nasional. Kelengkapan fasilitas merupakan syarat utama sebagai pendukung atraksi wisata. Keberadaan tourism display yang berisi informasi destinasi wisata sangatlah penting bagi para wisatawan. Tujuan kegiatan pengabdian adalah memberikan pengetahuan mengenai pengelolaan tempat pariwisata melalui perancangan papan informasi.  Tourism display menyediakan informasi yang dibutuhkan wisatawan di tempat wisata. Tourism display dapat berupa informasi tentang tempat wisata, seperti kondisi geografi, sejarah, harga, larangan, dan peringatan di tempat wisata. Terbatasnya ketersediaan tourism display di tempat wisata disebabkan oleh beberapa hal seperti belum matangnya perencanaan ruang tata kelola tempat wisata, hasil analisis kebutuhan yang belum mencantumkannya, dan pengetahuan teknis pembuatan papan informasi yang minim. Perancangan papan informasi wisata merupakan solusi untuk mengenalkan budaya promosi wisata. Hasil pengabdian menunjukkan 96% masyarakat merasa sangat puas. Perancangan papan informasi dapat menjadi penggerak masyarakat lokal untuk menambah pengetahuan terkait promosi wisata. Kata kunci: pariwisata, atraksi wisata, papan informasi wisata
PKM Budidaya Cacing Sutra (Tubifek Sp.) di Lahan Pekarangan Kelurahan Guntung Manggis Kecamatan Landasan Ulin Kota Banjarbaru
Authors: Fatmawati Fatmawati , Bijaksana Untung , Almuhasibi Muhammad Hudan , Qomariah Siti
Published: November 2022

AbstractSilkworm (Tubifex sp). is a good natural food for ornamental fish. Silkworms contain about 57% protein and 13% fat. Silkworms are natural food for fish seeds that are highly nutritious. The problem is not knowing how to cultivate silkworms and the available land has not been utilized. The solutions offered are the use of yards for silkworm cultivation, methods of counseling activities and demonstration of silkworm cultivation, evaluation of knowledge and skills before and after the activity is carried out. The results of the evaluation were analyzed by means of a two-party t-test according to Sudjana (1992). The results of the analysis show that the average value of the knowledge and skill of the target audience for all questions asked before the activity and after the activity is carried out is significantly different. The average value of the knowledge level of the target audience for all questions asked before the activity was 7.3 and increased to 34.7 after the activity was carried out. Average value of the skill, the target audience for all questions asked before the activity was 7.1 and increased to 35.1 after the activity was carried out. The   pilot activity has installed as many as two silkworm racks, so that partners can optimize their yards into productive land.  Key word : silkworm; counselling; knowledge; skill
Efeito alelopático de Tecoma stans, na germinação e crescimento inicial de Lactuca sativa e de três espécies nativas da Bacia do Rio Pirapó- PR
Authors: Garcia Letícia Mônica , Pastorini Lindamir Hernandez , Souza Luiz Antonio de
Published: November 2022

Com o objetivo de avaliar a possível atividade alelopática de Tecoma stans (L.) Juss. ex Kunth (amarelinho) sobre a germinação e o crescimento inicial de alface e de três espécies nativas, por meio de bioensaios laboratoriais, foram obtidos extratos aquosos de folhas de T. stans, coletadas de vários espécimes. Nos bioensaios de germinação, cipselas de alface e sementes das espécies nativas foram submetidas a extratos aquosos de T. stans nas concentrações de 1, 2, 4, 8 e 10% e água destilada como controle. Para análise do crescimento inicial foi obtido o comprimento da raiz e do hipocótilo de plântulas submetidas aos diferentes extratos aquosos. As concentrações mais altas dos extratos de T. stans inibiram a germinação de Lactuca sativa L., Peltophorum dubium (Spreng). Taub., Parapiptadenia rigida (Benth.) Brenam e Anadenanthera colubrina (Vell.) Brenan e influenciaram negativamente o crescimento inicial das plântulas. Quanto a porcentagem de germinação, T. stans apresentou 100%, evidenciando o potencial desta planta, comparado as espécies nativas testadas que apresentaram valores significativamente inferiores. Com isso, T. stans teria vantagem sobre as demais espécies, por apresentar maior PG e efeito alelopático, afetando o TMG, o comprimento da raiz primária (CRP) e o crescimento inicial, o que poderia comprometer o estabelecimento dessas espécies nativas no ambiente.
Disponibilidade hídrica e as anomalias climáticas no cultivo de soja e milho no Cerrado
Authors: Santos Gilmar Oliveira , Rodrigues Martins Guilherme , Rezende Blat Nathan , Barbosa Mendonça Layson
Published: November 2022

O balanço hídrico climatológico decendial (BHCD), é uma das principais formas de monitorar o armazenamento de água no solo, sendo essencial ao planejamento agrícola. Portanto, o objetivo deste estudo foi desenvolver o balanço hídrico climatológico sequencial (BHCS) e os efeitos das anomalias climáticas para o município de Rio Verde, Goiás, para as safras de 18/19 a 20/21. Foi simulado o plantio da soja no dia 25 de setembro e 25 de outubro, para os diferentes anos agrícolas, 18/19, 19/20 e 20/21. Em anos com influência do fenômeno El Niño, com intensidade fraca ou moderada, houve antecipação e melhor distribuição temporal das chuvas, propiciando a disponibilidade de água no solo e consequentemente a semeadura da cultura da soja após o término do vazio sanitário (25 de setembro), favorecendo ao desempenho da cultura da soja e em sucessão a cultura do milho. Em anos com influência do fenômeno La Niña, houve irregularidades das chuvas, com atraso do início do período chuvoso e má regularidade temporal, propiciando a deficiência hídrica e consequentemente atrasando a semeadura em alguns dias, além de comprometer a produtividade no período de safra (soja) e safrinha (milho). Como as anomalias climáticas podem variar a sua intensidade, mais anos agrícolas deverão ser levados em consideração para em um futuro breve, ser possível estabelecer a relação direta entre fenômenos climáticos, chuva e produtividade.
Price Dynamics and Integration in India's Staple Food Commodities – Evidence from Wholesale and Retail Rice and Wheat Markets
Authors: Sendhil Ramadas , Arora Kashish , Kumar Sunny , Lal Priyanka , Roy Arnab , Varadan Ramalingam Jayakumara , Vedi Sivasankar , Anandan Pouchepparadjou
Published: November 2022

Uncertain price movement in staple food commodities puts agrarian economies at risk if not monitored and managed consistently. Hence, an attempt has been made to analyze the price behavior and integration across major wholesale and retail markets for rice and wheat in India. Monthly data (July 2000 to June 2022) on prices viz., wholesale and retail were sourced from the Food and Agriculture Organization and analyzed using growth rate, instability index, seasonal price index, Johansen’s test on cointegration, Granger causality test, and impulse response function. Findings indicated strong evidence of price dynamics in the selected markets in terms of spatial and temporal variation, clear-cut seasonality linking to production, and price divergence between wholesale and retail markets. Johansen’s test indicated a strong integration between wholesale and retail markets exhibiting unidirectional-, bidirectional- and no-causality. Impulse response analysis revealed that the selected wheat and rice markets are efficient in terms of ‘price discovery’ which takes place initially in the wholesale market, and then transmitted to the retail market. The study advocates decision-making information to the producers, traders, and consumers who have a potential interest in getting advantage of the price movement. It is concluded that strengthening market intelligence and reducing the distortion in markets will improve the existing overall performance.
Post-COVID Endocrine Disorders: Putative Role of Molecular Mimicry and Some Pathomorphological Correlates
Authors: Normatov Muslimbek Ghulomovich , Karev Vadim Evgenievich , Kolobov Andrey Victorovich , Mayevskaya Vera Arkad'yevna , Ryabkova Varvara Aleksandrovna , Utekhin Vladimir Josefovich , Churilov Leonid Pavlovich
Published: November 2022

The article is devoted to the problem of autoimmune diseases provocation by coronavirus infection and the role of molecular mimicry in this phenomenon. SARS-CoV-2 can disguise its proteins as human ones in order to avoid immune attack. A bioinformatics analysis of the probable pentapeptide sharing between human autoantigens of endocrinocytes and SARS-CoV-2 spike protein, membrane protein and nucleocapsid protein was performed. Antigen mimicry between S-proteins of all other known human Coronaviruses and typical target autoantigens of endocrinocytes was also explored. Six human-identical regions were found in the SARS-CoV-2 membrane and nucleocapsid proteins, all of them in their immunodominant epitopes. All shared epitopes belong to antigens of endocrine cells commonly targeted during autoimmune endocrinopathies. Moreover, samples of the pituitary, adrenal and thyroid from patients who died from coronovirus infection (COVID-19) were studied morphologically using histochemical methods. A high frequency of SARS-CoV-2 caused inflammation of the studied endocrine organs was found in patients who died from severe COVID-19. At the same time, the abundant expression of virus antigens by the cells of the adenohypophysis was combined with the complete absence of its expression by the cells of the neurohypophysis. SARS-CoV-2 infected cells apparently perished by non-apoptotic pathway. The foci of lesions in endocrine organs contained abundant lymphocytic infiltrates which may witness for the impact of autoimmune processes. The facts revealed emphasize the need of endocrinological diagnostic alertness of a physician while observing patients with post-vaccination and post-COVID-19 health disorders. [3 figures, 6 tables, bibliography: 45 references].
Natural products as Potential Inhibitors of APH(3')-IIIa of Enterococcus faecalis: An In-silico Perspective
Authors: Carpio Arévalo Juan Marcelo , Amorim Juliana Carolina
Published: November 2022

Enterococcus faecalis is a bacterium that can develop a multidrug resistance profile associated with the community as well as nosocomial-acquired infections. Among the treatment options for these infections are aminoglycosides combined with bacterial cell wall inhibitors such as beta-lactams, since E. faecalis is intrinsically resistant to aminoglycosides. One of its most representative resistance mechanisms is the expression of aminoglycoside-modifying enzymes, such as the aminoglycoside phosphotransferase type IIIa of E. faecalis (EfAPH(3')-IIIa). This enzyme acts by phosphorylating aminoglycosides in an ATP-dependent reaction, modifying the 3' position of hydroxyl groups of these antibiotics. Considering this scenario, 3,092 natural products obtained from the ZINC22 database were analyzed to select molecules with the highest affinity for the nucleotide-binding pocket of EfAPH(3')-IIIa, which could be potential aminoglycoside adjuvants. The molecules that showed the best-score results obtained from ensemble docking-based virtual screening were ZINC000000952700 (BS-1), ZINC000014793040 (BS-2) and ZINC000015498603 (BS-3). The most promising results were for BS-2, a flavone derivative, due to its improved stability profile in molecular dynamics simulation (average values of RMSD of 0.23 nm, and Rg of 1.94 nm), binding free energy calculations (average ΔG total of -35.3 nm), as well as better toxicological profile (lower probability of hepatotoxicity, carcinogenic, immunotoxicity, mutagenicity, and cytotoxicity effects), compared to BS-1 and BS-3. These results allow us to propose that a flavone derivative may act as an adjuvant to aminoglycosides in the treatment of E. faecalis infections, acting as an inhibitor in the nucleotide-binding pocket of EfAPH(3')-IIIa.
Elucidating the Role of Santalol as A Potent Inhibitor of Tyrosinase: In Vitro and In Silico Approaches
Authors: Ali Nabeel , Zehra Zainy , Shamsi Anas , Beg Md Amjad , Parray Zahoor Ahmad , . Israil , Imam Md. Ali , Gaur Naseem A. , Hassan Md Imtaiyaz , Chaudhary Anis Ahmad , Rudayni Hassan A. , Alghonaim Mohammed Ibrahim , Alsalamah Sulaiman A. , Islam Asimul
Published: November 2022

This research work focuses on the potential application of an organic compound, santalol obtained from santalum album in the inhibition of the enzyme tyrosinase which is actively involved in the biosynthesis of the melanin pigment. Over-production of melanin causes undesirable pigmentation in humans as well as other organisms that significantly downgrade their aesthetic value. The study is designed to explain the purification of tyrosinase from the mushroom Agaricus bisporus, followed by activity assay and enzyme kinetic to give insight into the santalol modulated tyrosinase inhibition in a dose dependent manner. The multi-spectroscopic techniques like UV-vis, fluorescence, and isothermal calorimetry are employed to deduce the efficiency of santalol as potential candidate against the tyrosinase enzyme activity. Experimental results are further verified by molecular docking. Santalol derived from the essential oils of santalum album, is widely used as remedy for skin disorders and potion for fair complexion since ancient times. Based on enzyme kinetics and biophysical characterization, this is the first scientific evidence where santalol inhibits tyrosinase, which may be employed in agriculture, food, and cosmetic industries by prevent excess melanin formation or browning.
Quality Evaluation of Saudi (Moringa Alfileria) Honey: Antimicrobial, Antioxidant Activities, Physiochemical Properties and Melissopalynological Analyses
Authors: Hegazi Ahmed G , Al Guthami Fayez M. , Algethami Ahmed F. , Ramadan Mohamed F.A. , Craig Morrie , El-Seedi Hesham R. , Serrano Salud
Published: November 2022

Objective: The aim of the study was to characterize varieties of Moringa alfileria honey (unfloral and polyfloral) from Saudi Arabia based on antibacterial, antioxidant activities, physicochemical, melissopalynological analysis, total phenolic and flavonoid contents. Material and Methods: The fresh 376 honey samples (3 kg of each) were kindly provided by Alnahal aljwal Company, 2021 flowering season. The honey samples collected in sterile universal glass containers and kept at 2– 8°C until tested. Antibacterial, antioxidant activities and physiochemical analysis were done. Determination of sediment content, total grains, moisture content, water-soluble solids, acidity, electrical conductivity, total sugars content, inverted sugars, glucose (g/100 g), fructose (g/100 g), total glucose + fructose, fructose/ glucose ratio, sucrose (g/100 g), diastase enzyme activity and HMF were calculated. As well as total phenolic and flavonoid contents Results: Antibacterial activity and physiochemical analysis of honey samples w varied. All parameters studied were significantly different (P < 0.05) among all honey varieties. The results of the physiochemical analysis were compared with Saudi National Standard, Codex standard, as well as published data in the literature. Conclusion: It was obvious that the honey quality was varied based on the botanical origins
Ceuta
Authors: Trujillo Cruz Michelle
Published: November 2022

Texto de creación literaria en el que relato mi experiencia al cruzar la frontera entre Ceuta y Marruecos en el año 2019. En este escrito se rescatan ideas como lenguaje, otredad y fenómenos migratorios. De igual manera, propongo que Ceuta podría ser un símil de lo que fue el al-Ándalus en la península ibérica.
Reinserción social
Authors: González Rodríguez Jorge Enrique
Published: November 2022

Reflexiona sobre los retos que enfrentan las personas que han estado privadas de la libertad, aún después de cumplir su sentencia. También lo hace desde el ejercicio de la docencia y manifiesta el desconocimiento de la reinserción social por parte del estudiantado. De la misma manera, el autor enfatiza la importancia de sensibilizarnos y sumar diferentes grupos sociales en el proceso de reinserción.
Carta de Fidel Castro a Enrique Borrego, marzo 17 de 1958
Authors: Orozco Victor
Published: November 2022

Poseo una copia de esta carta escrita de puño y letra de Fidel Castro, gracias a mis amigos profesores Teodoro Montes e Imelda Vega, quienes me prestaron un viejo libro en el cual encontré el papel original cuidadosamente doblado.
La interpretación jurídica como herramienta para los juristas
Authors: Pacheco Darian Larissa
Published: November 2022

La interpretación jurídica y sus alcances resultan ser algunos de los temas más relevantes en la actualidad. Es por ello que también resulta imprescindible dar cabida al análisis del impacto que tiene, no sólo dentro de los procesos que buscan dar solución a un conflicto dentro de un caso concreto, sino también para el mejoramiento social. Asimismo, es menester esclarecer quiénes son aquellas personas encargadas de realizar dicha tarea interpretativa, sus límotes y como es que la llevan a cabo.
Leer a Daniel Sada en su obra maestra
Authors: Amparán Acosta Joel Abraham
Published: November 2022

Una obra que combina tal forma y magnitud no se produce de la noche a la mañana. Se dice que en Porque parece mentira la verdad nunca se sabe el lenguaje es el máximo protagonista.
Rituales políticos en los grupos étnicos de México
Authors: Ronquillo Arvizu Martín , Sempio Durán Camilo
Published: November 2022

El presente texto es una especie de guía para realizar el registro, de los rituales políticos en poblaciones indígenas de México, ya que de forma sintética nos permite enunciar las características más relevantes, definiendo de manera puntual, el cómo comprender los rituales políticos, más que ser un texto meramente académico tiene la intención de facilitar y difundir el registro documental de los rituales.
Presentación Dossier: Centenario de la publicación bilingüe del Tractatus Logico-philosophicus (1922-2022)
Authors: Hernández Marquez Víctor M.
Published: November 2022

Los textos aquí reunidos representan las versiones corregidas y mejoradas de las intervenciones realizadas en la mesa conmemorativa por el centenario de la publicación bilingüe del Tractatus lógico-philosophicus (1922-2022), llevada a cabo el 13 de mayo dentro de las jornadas filosóficas organizadas por el programa de Doctorado en Filosofía con acentuación en Hermenéutica y Estudios Socio-Culturales, del Departamento de Humanidades de la UACJ.
El centenario del Tractatus de Wittgenstein
Authors: Gasson Esteban A.
Published: November 2022

Este año se cumple un centenario de la publicación original del Logisch-philosophische Abhandlung–Tratado lógico-filosófico-, mejor conocido como el Tractatus de Ludwig Wittgenstein. Obra extremadamente breve y densa que aparecía después de muchas peripecias personales, pues su autor batalló para que pudiera ser publicada y después de varios intentos fallidos, cuando ya estaba a punto de desistir en su empeño, al fin se abrió la puerta en lo que sería el último número de la revista Annalen der Naturphilosophie, esto en el año de 1921.
11 de agosto, el jueves negro
Authors: Camarillo Jesus Hiram
Published: November 2022

Los juarenses vivieron el pasado 11 de agosto pasado una de las jornadas más violentas en años recientes, con los asesinatos de once personas, la quema de negocios y vehículos, balaceras aleatorias, así como el cierre masivo de negocios y escuelas.
Three decades of The Necks: Reciprocal Patterns of Improvised Music and Organisational Behaviour
Authors: Rose Jeremy
Published: November 2022

This article explores the nature of organisational behaviour within a long-standing improvised music group and its reciprocal relationship with their musical practice. It uses ideas from Ingrid Monson (1996) relating to social activities expressing the values and aesthetics of musical practice and adopts research findings from business management literature, in particular Kenneth Bettenhausen’s (1991) notion that the task patterns of a group play a role in shaping attitudes and behaviour, informing our understanding of the way improvisational music practices correlate with social and organisational behaviour.
The Australian piano trio, The Necks, perform minimalist extended improvisations with ritual-like patterns in performance and social behaviour. Being self-managed with the same line-up since 1987, they present a unique case study in how a band’s organisational behaviour has a mutual relationship to its musical practice. This study traces out their organisational patterns to show how these have developed in tandem with an improvisational ethos in which members undertake slowly evolving group minimalist improvisations guided by an unspoken set of behavioural patterns with adaptable parameters for change. The findings reveal an underlying narrative of tension between group homogeneity and individual autonomy, experiences of group flow, the use of varying modes of communication for varying contexts, similarities between their musical improvisation parameters and their social interaction, and strategies for implementing change and innovation. The article sketches how their social and organisational behaviour converges with their musical process: a slow rate of change, effortless, and yet with a long arc of possibilities.
Plan de marketing para el lanzamiento al mercado de almohadas premium personalizadas en San Isidro, La Molina, San Borja y Miraflores
Authors:   , Morales Calixto Lucciana Alexandra , Neyra Vargas Santiago Armando , Rodriguez Quispe Patrict Arom , Sulca Ramos Adela Nayheli
Published: November 2022

Nuestra idea de negocio surge debido a que en el contexto en el que vivimos existe un mayor porcentaje de personas con problemas para dormir ha aumentado a partir de la pandemia que inició en el año 2020. En esta nueva normalidad en la que desarrollamos nuestras tareas y vida diaria, existen personas que de forma continua tienen problemas para dormir, sufren de estrés, buscan alternativas para mejorar el sueño y esto es un conflicto que viene afectando a personas de todas las edades. Un problema como es el no poder descansar de forma adecuada trae consecuencias negativas como problemas para desarrollar la vida con normalidad, signos de estrés elevado, mal humor, al estar tantas horas sin poder descansar esto trae consecuencias negativas en la salud y en la vida personal de todas las personas. Para esto surge nuestra propuesta de poder fabricar y vender almohadas premium hechas a tu medida de material viscoelástico, las cuales te permiten dormir de mejor forma y tener un descanso pleno, para que puedas empezar tu día con toda la energía posible y no traiga consecuencias negativas en la salud. A partir de lo ya mencionado, el objetivo de nuestra investigación es determinar si es viable desarrollar y comercializar nuestro producto, es por esto que se realizará un análisis externo de los puntos más relevantes para el trabajo. Esto acompañado de las cinco fuerzas de Porter nos permitirá identificar nuestro FODA y FODA cruzado, para poder desarrollar las estrategias para nuestro producto. Además, plantearemos la misión, visión y valores adecuados para lograr alcanzar nuestros objetivos, estos serán medibles, claros y alcanzables. También realizaremos entrevistas en profundidad para poder obtener información más detallada de expertos y encuestas realizadas a nuestro público objetivo lo cual nos ayudará…
Propuesta de importación y comercialización de atún Costa Azul de Ecuador a Perú de la empresa ZV Inversiones Generales SAC
Authors:   , Ccancce Morales Sonia , Granados Retiz Silvana Jakeline , Guevara Chavez Aleidith , Mauricio Timoteo Joel Jack
Published: November 2022

El atún es un producto de gran consumo por las familias de todos los niveles sociales por su bajo precio, valor nutritivo y beneficios para la salud. Las variedades en sus presentaciones permiten satisfacer el paladar del público que le gusta consumir este pescado en conserva. Por su gran aceptación, las empresas comercializadoras eligen este producto ya que tiene un lugar ganado en el mercado, además su cadena de distribución es bastante amplia, siendo la más habitual el colocar el producto en supermercados, tiendas y bodegas de todos los sectores de la capital limeña. Una característica fundamental que motiva su consumo es la estrategia utilizada para la marca, de esta forma la identificación genera un gran respaldo al producto y su imagen frente al público que lo consume. Así mismo, las cadenas más representativas de autoservicios de la ciudad de Lima se dedican al comercio de productos importados, en ese sentido podemos analizar el comportamiento de compra del consumidor final de atún en conserva, quien delibera entres optar por un producto con marca de fabricante o marca de distribuidor, a fin de determinar e identificar su perfil y su comportamiento de compra. Así mimo analizaremos la problemática de la empresa en su búsqueda por lograr la internalización a través de la importación de conservas de atún procedentes del Ecuador, a fin de ampliar sus horizontes y poder posicionarse con su marca a nivel nacional.
Correlación entre el concepto y la práctica de automedicación responsable en los adultos mayores de la IPRESS Gamarra en el mes de junio del 2022
Authors:   , Huancahuari Torres Marlene Ines
Published: November 2022

La Organización Mundial de la Salud (OMS) admite la automedicación responsable para calmar los síntomas de baja gravedad (odinofagia, dispepsia, otalgia, tos). Si bien con esto se logra aliviar de forma temporal la sintomatología pueden generar a largo plazo un problema para el gobierno o el paciente al incrementar el gasto por un problema que pudo haber sido tratado adecuadamente si se impartía el tratamiento correcto a tiempo y por el personal de salud calificado. (Escobar-Salinas, 2017, p.19). Los principales motivos que influyen en la automedicación son: disponibilidad de medicamentos, recetas de venta libre, factores económicos, disponibilidad de horario de consulta, prejuicios, comportamiento ante la enfermedad, etc. e incluso confiar en el farmacéutico. Este enfoque también tiene un gran impacto. (Fajardo,2013). Esta actividad es cada día más frecuente, y puede ser un potencial problema en la gestión pública de la salud, que puede afectar la confiablidad y los resultados de los diversos tratamientos sobre todo para una población como los adultos mayores que padecen de enfermedades crónicas y utilizan muchos fármacos a la vez, a diferencia de otro grupo de edad, esta práctica es frecuente. Sin embargo, debe hacerse de manera responsable ya que necesita realicemos esta actividad de manera segura y responsable para utilizarlo en una enfermedad o condición crónica o recurrente que el paciente puede identificar después del diagnóstico médico inicial. De esta forma, se pueden reducir posibles riesgos como el ocultamiento de la enfermedad, las reacciones adversas e interacciones medicamentosas, el incremento de resistencias, la selección inadecuada de fármacos y el riesgo de abuso o dependencia del medicamento. (Ruelas, 2012)…