bluuebunny/crossref_metadata_2025 huggingface dataset:
Transglutaminase 2: A keystone in the molecular puzzle of cancer
Authors: Amin Tasbir , Rahman Kazi , Fakruddin Md , Bakhtiar UL Islam S M
Published: July 2024

Transglutaminase-2 (TG2), an enzyme also referred to as tissue transglutaminase, is ubiquitously present in a wide range of tissues, cell types, and subcellular compartments. Extensive research has demonstrated its involvement in both physiological cellular processes and pathological conditions. Studies investigating the diverse range of actions and multitude of targets associated with TG2 have significantly contributed to the understanding of its role in various types of cancer. This association is established through its interaction with pathways implicated in the initiation, progression, and ultimate spread of tumors. Furthermore, recent findings indicate that TG2 has a role in modifying the biomechanical milieu and signaling inside the tumor microenvironment, alongside mediating cancer cell behavior and intracellular signaling. In this review, we aim to elucidate the existing understanding of TG2’s involvement in cancer, with a specific emphasis on its functions in translating external signals into the initiation of oncogenic processes. Enhanced comprehension of these pathways may potentially pave the way for novel treatment approaches aimed at modulating this versatile protein.
Association between Type 2 diabetes mellitus and gastrointestinal cancers: A meta-analysis
Authors: Thomas Annie , Jinto EG , Jacob Jini Sara , George Preethi Sara , Mathew Aleyamma
Published: July 2024

Background: We analysed the association between Type 2 Diabetes Mellitus and pancreatic cancer (PaC), liver cancer (LC) and colo-rectal cancer (CRC) along with sub-group analysis on risk modification by duration of diabetes and gender-based differences. Methods: A systematic literature search was conducted using Pubmed, Google scholar, Medline and Scopus for observational studies on DM and gastro-intestinal cancers published over two decades from January 2005 till March 2023. Accordingly, 36 studies were selected (14 case-control and 22 cohort studies) estimated summary odds-ratio (OR)/risk-ratio (RR) using Mantel-Haenzel method along with 95%CI. Results: Among cohort studies, CRC showed highest risk (pooled RR=2.49, 95%CI: 2.43-2.54) followed by PaC (RR=2.06, CI:2.0-2.13) and LC (RR=1.70, CI:1.6-1.81). Among case-control studies, LC showed highest risk (OR=3.16, CI: 2.89-3.46) followed by PaC (OR=2.8, CI:2.48-3.17) and CRC (OR=1.43, CI:1.3-1.57). Risk of PaC with DM duration showed Only cohort studies of 2.31 (CI: 2.20-2.43) for DM <5yrs and RR of 1.67 (CI:1.57-1.77) for ≥ 5yrs. Higher risk in females than males, except in LC where males showed higher risk irrespective of study design. In conclusion, diabetes and gastro-intestinal cancers showed positive association which varied with duration of DM. Shorter DM duration was associated with more risk for PaC. Screening for markers of PaC in new-onset DM is advantageous. LC and CRC that develop with increasing duration of DM need frequent screening and regular follow-up for early detection and timely intervention. Males with DM are at greater risk of LC and efforts to reduce contributing risk factors, mainly alcoholism, are imperative.
Non-ribosomally synthesized lipopeptides: Promising novel therapeutics for cancer treatment
Authors: Shishir Md. Asaduzzaman , Sultana Sanjida , Turna Jabin Taj , Akter Tanjina , Mim Sayma Jahan , Islam Rashedul , Tanvir Md. , Akther Yeasmin , Jahan Israt , Ferdous Umme Tamanna , Prima Musharrat Jahan , Fakruddin Md.
Published: July 2024

Bacteria-derived non-ribosomally synthesized lipopeptides (NRLPs) present promising potential for cancer treatment, alongside their known antimicrobial, anti-inflammatory, and other pharmacological effects, due to their unique properties and modular assembly. However, addressing challenges such as toxicity, pharmacokinetics, and regulatory considerations necessitates an in-depth understanding of lipopeptides. This review provides extensive insights into the modular synthesis pathways, molecular mechanisms, structural diversity, and bioactivities of NRLPs. It highlights the remarkable potential of these lipopeptides as innovative therapeutic agents for cancer treatment. A significant portion of the review is dedicated to unraveling the sources, types, and bioactivities of NRLPs, with particular emphasis on their anti-cancer properties. The mechanisms underlying their efficacy against cancer cells, including apoptosis induction, cell cycle modulation, and interference with signaling pathways, are discussed. Envisioning the future of cancer therapeutics, the review concludes by outlining strategies for improved peptide design, integration with existing therapies, innovative and targeted cancer treatments, and the incorporation of emerging technologies. This comprehensive overview underscores the transformative potential of NRLPs in reshaping the landscape of cancer treatment.
Combination therapy of cisplatin and green silver nanoparticles enhances cytotoxicity and apoptosis in breast cancer cells
Authors: Heidari Majd Mostafa
Published: July 2024

Cisplatin is one of the first-line drugs for the treatment of breast cancer and is known for its ability to disrupt cancer cell DNA. However, cisplatin chemotherapy carries side effects and the risk of drug resistance. A strategy to improve its anti-cancer efficacy while reducing its negative effects on health is to leverage the synergistic potential of natural molecules with cisplatin. In this study, we explored combination therapy using cisplatin along with biosynthesized silver nanoparticles (Ag NPs) to enhance apoptosis induction in MCF-7 breast cancer cells while reducing cisplatin resistance. The biosynthesized Ag NPs, derived from Acacia Luciana flower extracts, possess active molecules that effectively inhibit MCF-7 cells. Concurrent administration of cisplatin and Ag NPs resulted in a notable decrease in the IC50 value – approximately 22 – 26 times lower compared to individual treatments of free Ag NPs and cisplatin, respectively. Furthermore, the combination therapy significantly increased the BAK1/BCLX ratio by 162-fold compared to the control, while the cisplatin alone failed to activate intrinsic apoptosis pathway. In addition, the expression level of the CASP3 gene, indicative of the extrinsic pathway of apoptosis, increased approximately 273 times compared to free cisplatin (CASP3 expression = 3.5). Notably, the combination therapy also reduced the expression of the AKT1 gene, associated with cell survival and treatment resistance, when compared to free cisplatin (1.87 vs. 4.488). In conclusion, our findings proved that combination therapy effectively enhances apoptosis induction by cisplatin while reducing drug resistance.
Long non-coding RNA DARS-AS1 facilitates breast cancer progression by modulating the miR-6835-3p/ATF3 axis
Authors: Vignesh Krishnamoorthy , Thangamalar Pattusamy
Published: July 2024

Long non-coding RNAs (lncRNAs) play crucial roles in various cellular processes associated with cancer progression, including invasion, proliferation, and metastasis. Despite this understanding, the specific role of DARS-AS1 in breast cancer remains underexplored. In this study, we employed quantitative reverse transcription-polymerase chain reaction to measure the expression levels of DARS-AS1 and miR-6835-3p. Functional assessments, including the cell invasion and CCK-8 assays, were conducted to investigate cellular behaviors. In addition, a luciferase reporter assay was employed to elucidate the mechanistic interaction between DARS-AS1 and miR-6835-3p. Notably, DARS-AS1 expression was elevated in breast cancer cell lines (MCF7 and MDA-MB-231) relative to the non-cancerous MCF-10A cells. Overexpression of DARS-AS1 enhanced cell growth and invasion in MDA-MB-231 breast cancer cells. Further investigation revealed that DARS-AS1 acts as a sponge for miR-6835-3p in breast cancer cells. Overexpression of miR-6835-3p inhibited luciferase activity, specifically in the presence of wild-type DARS-AS1, highlighting a direct interaction. Ectopic expression of DARS-AS1 suppressed miR-6835-3p in MDA-MB-231 cells. Concurrently, miR-6835-3p levels were downregulated in breast cancer cells, and miR-6835-3p exhibited a negative correlation with DARS-AS1 expression. Mechanistically, miR-6835-3p targeted ATF3 expression in breast cancer cells. Increased levels of DARS-AS1 were found to enhance cellular proliferation and invasion by modulating ATF3. Our findings indicate that DARS-AS1 acts as an oncogene in breast cancer, partially through regulation of the miR-6835-3p/ATF3 pathway. This study provides valuable insights into the molecular mechanisms contributing to breast cancer progression, offering potential targets for therapeutic interventions.
Überlegungen zum Konzept einer BzL-Sondernummer "10 Jahre 'Lehrerbildung von morgen'"
Authors: Reusser Kurt
Published: July 2024

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Lehrerbildung als Teil einer konsequenten Doppelqualifizierung
Authors: Albisser Stefan
Published: July 2024

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Die Neugestaltung der Seminarstundentafel nach pädagogisch-didaktischen Grundsätzen
Authors: Schmid Kurt
Published: July 2024

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Professionalisierung - Eine Rückschau auf Wurzeln und Wesen des LEMO-Berichtes
Authors: Müller Fritz
Published: July 2024

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Die Ausbildung der Ausbildner für die Lehrerbildung von morgen
Authors: Aebli Hans
Published: July 2024

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Von der Gleichwertigkeit zum Eintopf?
Authors: Rickenbacher Iwan
Published: July 2024

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Schule und Fernsehen
Authors: Messner Rudolf
Published: July 2024

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Wi(e)der eine neue Ausländerpädagogik?!
Authors: Steiner-Khamsi Gita
Published: July 2024

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Penggunaan Memetic Algorithm Pada Penjadwalan Mesin untuk Meminimumkan Emisi Karbon
Authors: Tampubolon Ferdinan Rinaldo , Devita Rischa , Siagian Sinta Marito , HS Samaria Chrisna , Purba Switamy Angnitha , Sitinjak Anna Angela
Published: July 2024

Isu lingkungan merupakan topik penelitian yang sering dilakukan akhir-akhir ini, salah isu tersebut adalah adalah emisi karbon. Salah satu gas emisi karbon terbesar muncul dari tindakan-tindakan manusia seperti transportasi, pertambangan, aktifitas konstruksi dan industri. Dari sisi operasional, strategi penjadwalan terbukti secara signifikan mengurangi emisi karbon. Strategi ini dianggap lebih efektif dan rendah biaya. Flexible Job Shop adalah salah satu jenis penjadwalan mesin pada industri dan merupakan pengembangan dari Job Shop. Kebanyakan penelitian terkait Flexible Job Shop menggunakan waktu pemerosesan bilangan crisp, pada kenyataannya faktor keterlibatan manusia, kerusakan mesin, maupun penurunan kinerja mesin mengakibatkan adanya ketidakpastian pada waktu pemerosesan pekerjaan, penelitian ini akan menyelesaikan Penjadwalan Flexible Job Shop dimana waktu pemerosesan dalam bentuk bilangan grey dengan dua fungsi tujuan yaitu makespan dan emisi karbon. Memetic Algorithm yaitu kombinasi algoritma NSGA-II dan Tabu Search digunakan untuk menyelesaikan kasus ini, hasil yang diproleh kombinasi algoritma ini memberikan hasil yang lebih baik dibandingkan penggunaan satu algoritma.
Pengaruh Penerapan Teori Belajar Vygotsky Terhadap Sikap Sosial Siswa Kelas II Pada Pembelajaran Matematika Sdnu Pemanahan Bantul
Authors: Munawaroh Isti , Syafriza Azizatul Alif
Published: July 2024

Keberhasilan proses belajar ditunjukkan adanya perubahan positif. Keterampilan dalam berkreasi, kecakapan dalam berbahasa serta dapat menemukan cara baru dalam belajar dapat dikatakan sebagai tanda bahwa proses belajar berhasil. Penelitian ini bertujuan untuk mengetahui pengaruh dari teori belajar Vygotsky terhadap sikap sosial siswa kelas II di SDNU Pemanahan Bantul. Jenis penelitian ini merupakan penelitian survei. Penelitian dilaksanakan pada bulan Juli hingga September 2023. Penelitian ini bertempat di SDNU Pemanahan Bantul. Subjek dalam penelitian ini adalah siswa kelas II, dengan populasi seluruh siswa kelas II di SDNU Pemanahan Bantul. Teknik pengumpulan data menggunakan kuesioner dan pedoman wawancara. Instrumen pengumpulan data dalam penelitian ini menggunakan kuesioner (angket). Skor penilaian angket dianalisis menggunakan konstrak untuk mengetahui validitasnya, sedangkan Alpha Cronbach untuk mengetahui reliabilitasnya. Hasil penelitian yang telah dilakukan, menyatakan bahwa teori belajar Vygotsky berpengaruh terhadap sikap sosial siswa. Pernyataan tersebut dapat dilihat dari nilai t hitung variabel sebesar 5,548 sedangkan nilai t tabel pada tingkat signifikan 5% (0,05) dan df21 (23-2) sebesar 1,721 yang berarti t hitung > t tabel (5,548 > 1,721). Nilai signifikansi yaitu sebesar 0,000 yang berarti lebih kecil dari 0,05 maka dapat dikatakan bahwa Ho di tolak dan Hi diterima. Penelitian ini menunjukan bahwa sikap sosial telah dimiliki siswa melalui teori belajar Vygotsky yang diterapkan di SDNU Pemanahan. Berdasarkan hal tersebut, maka penerapan dari teori belajar Vygotsky memberikan pengaruh yang baik terhadap sikap siswa dalam berinteraksi sosial. Penerapan tersebut dapat dilakukan di berbagai tingkatan kelas, untuk membiasakan siswa bersosial antar teman.
Penerapan Model Pembelajaran Berbasis Proyek Pada Pembelajaran Matematika Materi Kesebangunan di SMP Negeri 3 Ulunoyo
Authors: Laia Valentinus Operianus , Harahap Amin , Abduh Jamaluddin
Published: July 2024

Tujuan penulisan best practice ini adalah sebagai salah satu upaya peningkatan keaktifan  siswa kelas VIII melalui model pembelajaranproject based learning pada materi Kesebangunan. Penelitian ini dilakukan di SMP Negeri 3 Ulunoyo Kabupaten Nias Selatan. Metode penelitian ini adalah Penelitian Tindakan Kelas (PTK)  yang dilakukan secara  kolaboratif.  PTK  Kolaboratif  dilakukan  dengan  bekerjasama  antara  peneliti dengan  Guru  yang  tujuannya  untuk  peningkatan keaktifan  siswa kelas VIII SMP Negeri 3 Ulunoyo Kabupaten Nias Selatan. Subjek Penelitian ini adalah siswa VIII SMP Negeri 3 Ulunoyo Kabupaten Nias Selatan Kelas 8. Hasil yang diperoleh adalah: (1. Berdasarkan skor rata-rata aktivitas peserta didik dari 10 aspek pada lembar observasi peserta didik adalah 84%, Maka dapat disimpulkan bahwa aktivitas peserta didik penerapan model pembelajaran berbasis proyek materi kesebangunan untuk pertemuan pertama siklus 2 tergolong kategori aktif atau kategori baik. (2. Berdasarkan tabel tes hasil belajar peserta didik ditemukan rata-rata nilai 83.03, maka dapat disimpulkan bahwa model pembelajaran berbasis proyek kegiatan pertemuan pertama siklus 2 pada kategori Baik. Dari kedua kategori hasil penelitian diatas dapat disimpulkan bawah model pembelajaran berbasis proyek (project based learning) sangat baik untuk meningkatkan aktifitas, kreatifitas dan hasil belajar peserta didik pada pembelajaran matematika materi kesebangunan di SMP Negeri 3 Ulunoyo.
Pengaruh Pajak, Ukuran Perusahaan, dan Profitabilitas terhadap Keputusan Perusahaan Melakukan Transfer Pricing
Authors: Olimsar Fredy , Misidawati Dwi Novaria , Marpaung Rumintar J. H. , Setiawan Heri , Utami Eva Yuniarti
Published: July 2024

This research aims to test and obtain empirical evidence regarding the influence of taxes, company size, probability on transfer pricing. This research uses a sample of subsector manufacturing companies... listed on the Indonesia Stock Exchange in 2019-2023. The sampling method used in this research is the purposive sampling method using SPSS for data analysis. This type of research is quantitative with 150 companies used as research samples with observations for 5 years, so the total research sample is 70 samples. The analysis technique used is regression. The results of this research show that simultaneously, tax, company size, and probability have an influence on companies carrying out transfer pricing.
Strategi Dakwah Penyuluh Agama Islam Dalam Peningkatan Pemahaman Praktik Ibadah Kemasyarakatan
Authors: Sopiyan Wawan , Nurjanah Indah , Mislawati Sri Eva , Syamsul Encu M
Published: July 2024

Islamic religious outreach activities by Islamic Religious Counselors play an important role in increasing religious understanding in the Indonesian Islamic community. Even though the number of Islamic religious instructors is still very minimal, changes related to religious understanding in society are considered quite significant and are felt by the community. This research seeks to determine the Islamic Religious Extension Strategy carried out by Islamic Religious Counselors to increase understanding of community worship practices in Lubuk Linggau Ulu Village, Lubuk Linggau Barat 2 District, Lubuk Linggau City. The research was carried out by observing the activities held by Islamic Religious Counselors who provide religious counseling in the Lubuk Linggau Ulu sub-district and conducting in-depth interviews regarding the program of activities carried out. This research uses descriptive qualitative methods. Researchers in observations and interviews found that Islamic Religious Counselors in Lubuk Linggau Ulu Village, Lubuk Linggau Barat 2 District have implemented extension programs, especially programs related to increasing understanding and skills in community worship practices. The results of the research show that Islamic religious instructors in the Lubuk Linggau Ulu sub-district, Lubuk Linggau Barat 2 sub-district are implementing strategies by selecting priority programs, namely programs to increase community understanding, especially in terms of community worship practices because skills in caring for corpses, the knowledge of tajwid and understanding of the fiqh of daily worship are very important. useful and useful in society.
Magnitude of changes in muscle endurance in the Bering-Sorensen test and changes in balance in subjects with LBP treated with muscle energy techniques
Authors: Wegner-Czerniak Katarzyna , Mączyński Jacek_ , Błaszczyk Anna , Ogurkowska Małgorzata B.
Published: July 2024

Purpose

Manual therapy is used as a conservative treatment for people with low back pain (LBP). The scale of the problem encourages the search for the most effective methods to assess of manual treatment. Therefore, the aim of the study was to investigate magnitude of changes in muscle endurance using the Biering-Sorensen test (BST) and to analyse balance in patients with LBP treated with ERS and FRS muscle energy techniques (MET).

Methods

The study included fifteen men with LBP (mean age: 42 years) working as automotive assemblers. Endurance of the biceps femoris (BF), gluteus maximus (GM) and erector spinae (ES) muscles were analysed using sEMG during the BST. The level of experienced pain, degree of disability and postural stability were also examined. Results before and after a three-week treatment cycle using MET were compared.

Results

The MET therapy resulted in a reduction in pain (p=0.001), an improvement in the degree of disability (p<0.001), and an increase in the duration of the BST (p<0.001). After therapy, the values of the NMFs parameter indicating the degree of fatigue increased, i.e. ES muscle endurance increased, both right (p=0.004) and left (p<0.001). There was also a statistically significant decrease in the centre of pressure (COP) movement velocity in balance tests.

Conclusions

The use of MET in patients with LBP increases muscle endurance, improves postural balance, and reduces pain levels on the VAS and disability levels according to the ODI. MET appears to be a good tool for preventing LBP.
Characteristics of walking techniques with different pelvic height and pelvic rotation: effects on muscle activation and energy consumption
Authors: Kapeleti Marko , Ubović Miloš , Ilić Duško , Mrdaković Vladimir
Published: July 2024

Purpose

Previous studies have proven that modifications in the natural walking technique alter muscle activation and energy consumption. This research aims to determine the differences in muscle activation, energy consumption, kinematic characteristics, perceived muscular exertion and perceived cardio-respiratory fatigue between natural and modified walking techniques with altered pelvic height and rotation.

Methods

Nine physically active, non-injured males walked on a treadmill. Modified walking techniques assumed maintenance of constant pelvic height and application of maximal pelvic rotation. Walking speed was subtransit – 0.4 km/h less than the transit. Sampled variables were average normalized maximal activation during contact and swing phase relativized to maximal voluntary activation, average submaximal oxygen consumption relativized to body mass and subtransit speed, average step length and frequency, rating of perceived muscular exertion and perceived cardio-respiratory fatigue. Muscle activation, energy consumption, and kinematic characteristics were assessed throughout each walking session. Perceived muscular exertion and perceived cardio-respiratory fatigue were evaluated post-session. Electromyographic activity was assessed for rectus femoris, gluteus maximus, vastus medialis, biceps femoris, tibialis anterior and gastrocnemius lateralis.

Results

The most significant changes in muscle activation were observed during the contact phase. A decrease in pelvic height increased muscle activation of rectus femoris, vastus medialis, and gastrocnemius lateralis. An increase in pelvic rotation increased muscle activation of all monitored muscles except gluteus maximus. Both modifications increased energy consumption, perceived muscular exertion and perceived cardio-respiratory fatigue, and altered kinematic characteristics.

Conclusions

Modifications in pelvic height and rotation at the same walking speed alter muscle activation, energy consumption, kinematic characteristics, perceived exertion and fatigue.
Developing professional ethical care through co-creation in ECEC in Norway: A qualitative study
Authors: Brenne Anne Synnøve , Amot Ingvild
Published: July 2024

The article analogizes findings from the project Children in Central Norway, Mental Health in ECEC. A preventive factor for children’s mental health in early childhood education and care (ECEC) is the sensitive relationship between children and staff. ECEC staff in three municipalities participated in a competence-raising package for children’s mental health. Subsequently, 33 members of staff attended five focus-group interviews. Research question: In what way have ECEC staff’s experience changes in their relationship with the children after working with the competence-raising package for mental health, and what kind of processes appeared during this work? The qualitative data has been analyzed using reflexive thematic analysis, while the discussion is rooted in ethics of care and based on children’s rights. The findings show that the staff describe the development of compassionate pedagogy and a common language for children’s needs for attachment. This facilitates a collective professional language through co-creating processes and affects the relational quality in ECEC.
Child citizenship and participation: Bottom-up level change from professional conversations with children
Authors: Casley Marilyn , Cartmel Jennifer , Smith Kerry , O’Leary Patrick , Reyes Bernard Natalie
Published: July 2024

Hart's (1992) 'Innocenti Essay on Child Participation' advocated for increased involvement of young people as active participants in societal decision-making. This paper provides a historical overview of active child citizenship initiatives, using applied research insights from 'bottom-up' approaches and conversations with children and professionals. It explores how current practices exemplified through three case studies can enhance genuine child participation and citizenship. The case study analysis examines the conversational processes involving children in problem-solving and decision-making within their communities. Through these examples, the paper highlights practical strategies for meaningfully engaging children as stakeholders and empowering them as active citizens whose voices substantially influence matters impacting their lives.
ROLE OF INTEGRINS IN HUMAN SPERM CELLS ON THE REPRODUCTION PROCESS
Authors: Aziza Noer , Pujianto Dwi Ari
Published: July 2024

Ovum and spermatozoa cells, namely male and female reproductive cells that unite at the time of fertilization, are synchronized molecular events that occur sequentially. Apart from being present in the egg cell, adhesion molecules called integrins are also involved in this molecular process. However, recently, these integrins have also been found in spermatozoa cells, especially in the head and tail areas. Because this problem is intended as an introduction to the laboratory which is part of the thesis research, the method used in this research is a literature review whose publication age is not more than 10 years. Research findings indicate that integrins play a crucial role in egg-sperm recognition, their interaction, and fusion, potentially addressing infertility issues in couples of reproductive age.
DIFFERENT PERSPECTIVES ON CHILDREN IN POSTMODERN FAMILY STUDIES IN CRETIVOX YOUTUBE BETWEEN YOUNG PARENTS AND CHILDFREE COUPLES
Authors: Putra Raafi Herdiansyah
Published: July 2024

The childfree phenomenon has become a popular issue in Indonesia recently. Many articles and media content address the topic of being childfree, including the eighth episode of the YouTube account Cretivox. This episode features two married couples with differing perspectives on having children. The purpose of this study is to explore the differences in perspectives on children in the household from the viewpoints of childfree couples and young parents, analyzed through a postmodern family approach. This research employs a qualitative approach and a descriptive method. Data collection involves documents from the Cretivox YouTube account and relevant journal articles. The results indicate that out of five questions posed, four reveal differing views: preparation before marriage, popular statements about children, the urgency of having offspring, and household harmony. For the question regarding children guaranteeing support in old age, both couples agreed to disagree with the statement.
THE EFFECT OF AGING POPULATION, FERTILITY RATES, AND POPULATION GROWTH ON ECONOMIC GROWTH IN INDONESIA
Authors: Tomi Sah  , Valeriani Devi
Published: July 2024

The declining fertility rate in Indonesia, coupled with an increasing aging population and continuous population growth, has become a national concern, leading to potential alterations in Indonesia’s economic landscape. This research delves into the ramifications of Indonesia's aging population, fertility rates, and population growth on its economic growth, employing a comprehensive analysis of time series data from 1961 to 2022. Utilizing multiple linear regression, this investigation aims to unveil the interconnectedness between demographic variables and economic advancement. This study found that the aging population has no statistically significant influence on economic growth. However, fertility rates demonstrate a notable negative impact on economic growth, while population growth showcases a significant positive influence on economic growth. These findings underscore the necessity for targeted policy interventions aimed at addressing demographic shifts to ensure sustainable economic development in Indonesia.
Pendekatan Desain Partisipatoris dalam Perancangan Board Game Sebagai Media Pembelajaran Bahasa Indonesia
Authors: Hananto Brian Alvin , Calista Helena , Suwandi Chelsey
Published: July 2024

Artikel ini membahas mengenai proses perancangan board game yang dilakukan dengan pendekatan desain partisipatoris. Melalui kerjasama dengan Sekolah GenIUS, penulis merancang dua board game yang diharapkan dapat berguna sebagai media penunjang pembelajaran dalam mata pelajaran bahasa Indonesia. Melalui tahapan-tahapan discover, define, develop, dan deliver, penulis menjalankan pendekatan partisipatif untuk bisa menggali dan melibatkan Sekolah GenIUS dalam perancangan yang dilakukan. Hasil dari perancangan ini disambut baik dengan antusiasme siswa-siswi Sekolah GenIUS yang dilibatkan dalam proses perancangan ini. Penulis berharap tulisan ini dapat menjadi referensi dari perancangan dengan menggunakan pendekatan desain partisipatoris, khususnya dalam merancang board game.
PENERAPAN SISTEM KREDIT SEMESTER MERDEKA BELAJAR DI SMA NEGERI 1 GRESIK
Authors: Jaenuri Jaenuri , Mulyani Sri
Published: July 2024

The purpose of writing this thesis is to determine the implementation of the Semester Credit System (SKS) at SMAN 1 Gresik. Curriculum changes from timeto time SMA Negeri 1 Gresik has become a reference school for other schools. Since the launch of Mover Schools by implementing the Kurikulum Merdeka (KUMER), it has become a challenge for school principals. As a school driving community pressure, it is inevitable to implement SKS. This is driven by the desire of the student's parents to graduate within 2 academic years. This research uses data collection techniques, triangulation method, data sources (triangulation data), researchers (triangulation investigator), as well as perspectives and theories). The results of the research showed that there were no technical guidelines for SKS in Mover Schools, so the school formed a school development team, carried out curriculum inovation and conveyed aspirations during the PMO (Project Management Office) assisting Mover Schools. SMAN 1 Gresik was the first to implement the SKS program with an independent curriculum.
El sonido del trueno: Cómics de dinosaurios y onomatopeya especulativa
Authors: Charmer Charlie , Narváez Padilla Iván
Published: July 2024

La onomatopeya es un recurso expresivo fundamental en el cómic que sintetiza texto e imagen. Su principal función es representar sonidos inarticulados extraños al lenguaje, como pueden ser las voces de los animales. Cuando se trata de criaturas extintas de las que no existen registros sonoros, como en el caso de los dinosaurios y otros animales mesozoicos, la onomatopeya adquiere una dimensión especulativa cuya concreción dependerá de la imaginación tanto del autor como del lector. La técnica más habitual ha sido utilizar referentes actuales, pero existen obras más personales que han creado un universo particular.
Fastwalkers de Ilan Manouach. La IA y el cómic conceptual
Authors: Peña Méndez Miguel
Published: July 2024

La publicación de Fastwalkers de Ilan Manouach ha supuesto una de las primeras creaciones reflexivas y ambiciosas realizadas mediante Inteligencia Artificial (IA) en el mundo del cómic. Alrededor de ella, el artículo revisa su trabajo, valorando lo que ello supone para el mundo de la creación de cómics tanto en sus repercusiones técnicas como conceptuales, y se exponen algunas ideas sobre sus implicaciones narratológicas, estilísticas y estéticas.
Diz Ağrıları
Authors: Konca Sinem Kübra , Cüce İsa , Akdeniz Çınar Firdevs , Ülkü Demir Fatma Gül , Yaprak Taş Esra , Güç Ayşe , Karabaş Çağlar , Sayan Hatice , Aktaş Elif , Cengiz Gizem , Yılmaz Büşra , Köksal Mehmet , Baygül Atalay Yurdagül , Kozan Ayşe Nur , Gökbelen Bilen Duygu , Yağmur Neslihan
Published: July 2024

Diz Anatomisi ve Biyomekaniği
Sinem Kübra KONCA
İsa CÜCE
Diz Muayenesi
Firdevs AKDENİZ ÇINAR
Fatma Gül ÜLKÜ DEMİR
Diz Ağrısı Nedenleri
Esra YAPRAK TAŞ
Ayşe GÜÇ
Diz Ağrılarında Laboratuvar Bulguları
Çağlar KARABAŞ
Sinovyal Sıvı Analizi
Hatice SAYAN
Diz Ağrılarında Görüntüleme Bulguları
Elif AKTAŞ
Diz Osteoartriti
Fatma Gül ÜLKÜ DEMİR
İnflamatuar Romatolojik Hastalıklarda Diz Tutulumu
Gizem CENGİZ
Çocukluk Çağında Gözlenen Diz Eklemi Rahatsızlıkları
Ayşe GÜÇ
Diz Ekleminin Neoplastik Hastalıkları
Büşra YILMAZ
Menisküs Lezyonları
Havva TALAY ÇALIŞ
Postoperatif Menisküs Rehabilitasyonu
Mehmet KÖKSAL
Diz Bağ Yaralanmaları
Yurdagül BAYGÜL ATALAY
Diz Bağ Yaralanmaları Tedavi ve Rehabilitasyonu
Ayşe Nur KOZAN
Diz Artroplastisi ve Rehabilitasyonu
Duygu GÖKBELEN BİLEN
Diz Osteoartritinde Farmakolojik ve Nonfarmakolojik Tedavi Yöntemleri
Neslihan YAĞMUR
İnternet ve Demokrasi
Authors: Uslu Mehmet , Kılınçoğlu Mehmet , Kardaş Orçun , Kaba Ümmü Gülsüm , Kadıoğlu M. Selin , Çağlar Mustafa , Ünlü Ayşe Betül , Şevgin Derya , Dükkel Gülşah , Akkaya Beyza Nur , Yakar Mehmet , Şevik Beyza Merve , Gökfidan Mustafa Gökhan , Avcı Elif Cansu , Ayyıldız Bilge , Özdemir Seyit Selçuk , Kaba Ebubekir , Aladağ Sinem , Sümer Asya , Abdulsalam Semah
Published: July 2024

Demokrasi kavramının tarihin farklı dönemlerinde, farklı tartışmalara konu olması, günümüzde bu tartışmanın çok daha farklı ve dijital bir boyutta incelenmesi süreciyle devam etmektedir. İnternet teknolojilerinin gündelik yaşamın her alanındaki, artık tartışmasız hale gelen etkisi, toplum yaşamında meydana gelen dönüşümlerin de kaynağında yerini almaya başlamıştır. Teknoloji ile birlikte gelişen ve değişen yaşamlar, sistemler beraberinde farklı tartışmaları da getirmektedir.
21.Yüzyıl Toplumunun Yeni Tanımı
Mehmet Uslu
Mehmet Kılınçoğlu
Orçun Kardaş
Teknolojinin Gelişen Sosyolojisi:
Ağ Toplumu
Ümmü Gülsüm Kaba
Selin Kadıoğlu
Ağ Toplumunun Yeni Demokrasi
Yorumu
Mustafa Çağlar
İnternette Demokrasi Kültürü Adana Büyükşehir Belediyesi Örneği
Ayşe Betül Ünlü
Derya Şevgin
Tarihsel Olarak Farklı Demokratikleşme Biçimleri
Tuğba Yolcu
Demokrata Karşı Netokrat
Gülşah Dükkel
Beyza Nur Akkaya
Demokratik Elitler ve Elitizm
Mehmet Yakar
Beyza Merve Şevik
Netokrasi ve Hukuk
Mustafa Gökhan Gökfidan
İnternet Sonrası Demokratikleşme ve Toplumsal Hareketler
Elif Cansu Avcı
Bilge Ayyıldız
Sivil İtaatsizliğin Kavramsal Çerçevesi ve Enformasyon Çağı
Seyit Selçuk Özdemir
Sivil İtaatsizlikte Sosyal Medyanın
Etkisi
Ebubekir Kaba
Bir Sivil Direniş Örneği:Hindistan Bağımsızlık Hareketi
Sinem Aladağ
Asya Sümer
Ortadoğu’da Netokratik İnşa: Suriye İç Savaşı
Semah Abdulsalam
Türk Müziğine Yönelik Çeşitli Tespitler II
Authors: Aydoğdu Can , Yoldaş Erkan , Aslancan Nesrin , Yeşilyurt Recep , Mandollu Seda , Göktaş Uğur , Dönmez Yağmur Eylül , Altun Yusuf
Published: July 2024

Geleneksel Törenlerimizde Müzik Unsurlarının Kullanımı
Can AYDOĞDU
Geçmişten Günümüze Diyarbakır Eyvan Geceleri Kültürü
Erkan YOLDAŞ
Geleneksel THM Mendil Kavramının Kullanım Özellikleri
Nesrin ASLANCAN
Hüzzam Makamı Dizisinin Bağlama ile Seslendirilmesinde Ortaya Çıkan Kuramsal Farklılıklar
Recep YEŞİLYURT
Gaziantep Yöresi Ninni Geleneği
Seda MANDOLLU
Başlangıç Düzeyi Bağlama Öğrenimine Etki Eden Faktörler
Uğur GÖKTAŞ
Mavi Boncuk Filminde Kullanılan Müzikler Üzerine Tespitler
Yağmur Eylül DÖNMEZ
Güzel Sanatlar Fakültesi Öğrencilerinin Müzik Kavramına İlişkin “Metaforik” Algıları
Yusuf ALTUN
Sarı
Authors: Özyürek Talat
Published: July 2024

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Geleneksel Siirt Mutfağı
Authors: Beştaş Şahin
Published: July 2024

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Supramolecular assemblies of amphiphilic donor–acceptor Stenhouse adducts as macroscopic soft scaffolds
Authors: Hung Ka-Lung , Cheung Leong-Hung , Ren Yikun , Chau Ming-Hin , Lam Yan-Yi , Kajitani Takashi , Leung Franco King-Chi
Published: July 2024

In the design of photoharvesting and photoresponsive supramolecular systems in aqueous medium, the fabrication of amphiphilic photoswitches enables a noninvasive functional response through photoirradiation. Although most aqueous supramolecular assemblies are driven by high-energy and biodamaging UV light, we have previously reported a design of amphiphilic donor–acceptor Stenhouse adducts (DASAs) controlled by white light. Herein, we present a series of DASA amphiphiles (DAs) with minor structural modifications on the alkyl linker chain length connecting the DASA motif with the hydrophilic moiety. The excellent photoswitchability in organic medium and the photoresponsiveness in aqueous medium, driven by visible light, were investigated by UV–vis absorption spectroscopy. The assembled supramolecular nanostructures were confirmed by electron microscopy, while the supramolecular packing was revealed by X-ray diffraction analysis. Upon visible-light irradiation, significant transformations of the DA geometry enabled transformations of the supramolecular assemblies on a microscopic scale, subsequently disassembling macroscopic soft scaffolds of DAs. The current work shows promising use for the fabrication of visible-light-controlled macroscopic scaffolds, offering the next generation of biomedical materials with visible-light-controlled microenvironments and future soft-robotic systems.
Pengaruh Waktu Fermentasi Terhadap Sifat-Sifat Anggur Beras Kencur yang dihasilkan
Authors: Radite Putut Wibowo  , Tunnisa Fitra , Darmawan Eman , Laswati Dyah titin , Sudjatini
Published: July 2024

Penelitian dengan judul pengaruh waktu fermentasi terhadap sifat sifat anggur beras kencur yang dihasilkan bertujuan untuk mengetahui pengaruh waktu fermentasi terhadap sifat-sifat anggur beras kencur. Untuk mengetahui waktu fermentasi yang optimal pada pembuatan anggur beras kencur yang disukai konsumen. Penelitian ini dilakukan dengan metode Rancangan Acak Lengkap (RAL), yang terdiri dari 5 perlakuan. Tiap perlakuan dilakukan pengulangan sebanyak 2 (dua) kali. Perlakuan tersebut meliputi umur fermentasi yaitu 0 hari, 1 hari, 3 hari, 5 hari, dan 7 hari. Masing masing sampel dilakukan analisa kimia dan organoleptik. Data yang diperoleh dilakukan uji lanjutan dengan metode Duncan Multiple Range Test (DMRT) pada taraf signifikan 5%. Parameter yang diuji meliputi analisa kimia kadar gula reduksi, etanol, total asam, total pati, dan pH serta analisa organoleptik (warna, rasa, aroma, dan kesukaan). Hasil penelitian menunjukkan bahwa waktu fermentasi yang terbaik pada 3 hari dengan kadar etanol 1,44 %, gula reduksi 0,44 %, total asam 0,42 %, kadar pati 9.34 %, pH 4.37, serta mempunyai rasa agak manis sedikit pahit dengan warna putih kecoklatan, aroma agak khas aroma anggur.
Pengaruh Tepung Maizena-Beras dan Asal Daerah Bawang Merah Terhadap Warna, Sifat Kimia, dan Tingkat Kesukaan Bawang Goreng
Authors: Izun Patihi Ibad  , Dwiyati Pujimulyani  , Agus Slamet
Published: July 2024

Pengolahan untuk memperpanjang masa simpan dan meningkatkan nilai ekonomi bawang merah yaitu dibuat menjadi bawang goreng. Tujuan penelitian ini yaitu mengetahui pengaruh bawang merah Bantul dan Brebes serta tepung maizena-beras terhadap warna, sifat kimia, dan tingkat kesukaan bawang goreng. Penelitian dirancang dengan Rancangan Acak Lengkap 2 variabel yakni variasi penambahan tepung maizena-beras 10:0; 5:5; dan 0:10 dan bawang merah yang digunakan (bawang Brebes dan Bantul). Produk bawang goreng yang dihasilkan diuji warna , kimia dan tingkat kesukaan. Data yang diperoleh distatistik menggunakan ANOVA dengan akurasi 95%, dan dilanjutkan uji Duncan (p<0,05) jika terdapat beda nyata. Bawang goreng terpilih berdasarkan tingkat kesukaan beserta kontrolnya kemudian dilakukan analisis kimia (kadar air, kadar abu, dan kadar lemak). Hasil penelitian menunjukkan adanya pengaruh yang nyata dari penambahan tepung maizena-beras dan bawang merah Bantul serta Brebes terhadap warna, sifat kimia dan tingkat kesukaan bawang goreng. Produk bawang merah goreng terpilih yaitu bawang goreng dengan bahan baku dari bawang merah Brebes dengan penambahan tepung maizena-beras 5:5. Hasil analisis kimia bawang goreng terpilih yakni memiliki kadar air sebesar 4,65%, kadar abu 3.06%, dan kadar lemak 17,89%.
Pegaruh Penambahan Minyak Jintan Hitam (Nigella sativa) terhadap Karakteristik Sensoris, Fisik, dan Kimia Susu Bubuk
Authors: Rusmadi Adi , Darmawan Eman , Saputro Asepto edi
Published: July 2024

Penelitian ini bertujuan untuk mengetahui konsentrasi optimal minyak jintan hitam yang dapat ditambahkan dan pengaruhnya terhadap karakter sensoris, kimia dan fisik susu bubuk. Penelitian ini menggunakan 7 perlakuan, yaitu susu bubuk skim yang di tambah dengan minyak jintan hitam pada konsentrasi 0%, 2.5%, 5%, 7.5%, 10%, 12.5%, dan 15%. Pengujian dilakukan dengan menggunakan uji sensoris (multiple comparison test dan uji hedonik), uji kimia (protein, lemak, kadar air, kadar abu, dan karbohidrat) dan uji fisik (wettability dan bulk density). Penambahan minyak jintan hitam berpengaruh terhadap karakter sensoris dan karakter kimia, namun tidak berpengaruh terhadap karakter fisik susu bubuk. Hasil penelitian menunjukkan bahwa secara umum tingkat kesukaan rasa, warna, aroma dan penerimaan keseluruhan susu bubuk dengan minyak jintan hitam menurun seiring dengan meningkatnya konsentrasi minyak jintan hitam yang ditambahkan. Konsentrasi optimal penambahan minyak jintan hitam adalah 2.5% dengan nilai gizi protein (37%), lemak (0.25%), kadar air (3.50%), kadar abu (4.73%) dan karbohidrat (54.52%). Nilai gizi tersebut sesuai kategori susu bubuk rendah lemak mengacu pada SNI 01-2970-1992 tentang susu bubuk (protein minimal 26%, lemak 1.5 hingga <26%, kadar abu maksimal 9%).
Karakteristik Kwetiau Gandum Substitusi Labu Kuning (Cucurbita moschata D) Dan Penambahan Sodium Tripollyphospate (STPP)
Authors: Purwadi Dani , Darmawan Eman , Kuntjahjawati SAR  , Masrukan
Published: July 2024

Telah dilakukan penelitian tentang “Karakteristik Kwetiau Gandum Substitusi Labu Kuning (Cucurbita moschata D) Dan Penambahan Sodium Tripollyphospate (STPP)”. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan STPP terhadap sifat fisik dan organoleptik kwetiau labu kuning serta mengetahui perbandingan antara tepung gandum dan labu kuning untuk mendapatkan kwetiau yang dapat diterima panelis. Hasil penelitian menunjukkan bahwa penambahan labu kuning dan STPP berpengaruh nyata terhadap karakteristik kimia dan organoleptik kwetiau. Penambahan labu kuning dan STPP menyebabkan terjadinya peningkatan kadar air dan elastisitas kwetiau namun terjadi penurunan kadar abu, lemak, protein dan karbohidrat. Hasil uji organoleptik menunjukkan bahwa penambahan labu kuning dan STPP menunjukkan hasil beda nyata terhadap warna, aroma, rasa dan keseluruhan. Perbandingan antara labu kuning dan konsentrasi STPP yang masih dapat diterima oleh konsumen ialah pada sampel dengan 20% penambahan labu kuning dan konsentrasi STPP sebesar 0,2%. Berdasarkan hasil uji kesukaan terhadap keseluruhan karakteristik kwetiau dengan nilai rerata 3,6 (suka) yang mengandung kadar air 29,86%, kadar abu 4,64%, kadar lemak 2,07%, kadar protein 11,45%, mutu organoleptik elastisitas dengan nilai 0,116 menghasilkan tekstur kwetiau yang elastis, warna kwetiau kuning oranye cerah, rasa kwetiau khas labu kuning, dan menghasilkan aroma kwetiau khas labu kuning.
Hubungan Pola Makan dan Stres dengan Siklus Menstruasi pada Remaja Putri di SMA Muhammadiyah 4 Yogyakarta Tahun 2023
Authors: Anggoro Sarni , F.U Azizah
Published: July 2024

Menstruasi adalah proses keluarnya darah kotor dari vagina Perempuan yang merupakan siklus bulanan rutin. Ketidakteraturan haid (menstruasi) menjadi masalah utama bagi setiap remaja dan hal tersebut merupakan sumber kecemasan utama bagi mereka. Faktor yang dapat menyebabkan terganggunya siklus mesntruasi yakni stres dan pola makan yang tidak baik atau teratur. Ketidakteraturan siklus menstruasi merupakan salah satu permasalahan yang terjadi pada remaja putri SMA Muhammadiyah 4 Yogyakarta. Penelitian ini bertujuan untuk mengetahui hubungan antara pola makan dan stres dengan siklus menstruasi  pada remaja putri di SMA Muhammadiyah 4 Yogyakarta. Metode penelitian yang digunakan yaitu penelitian kuantitatif dengan pendekatan Cross sectional. Dengan populasi dan sampel sebanyak 61 responden, menggunakan total sampling. Data dianalisis menggunakan Uji Chi Square. Instrumen penelitian menggunakan kuisioner. Berdasarkan hasil wawancara yang telah dilakukan di SMA Muhammadiyah 4 Yogyakarta didapatkan hasil yaitu dari 10 remaja putri 6 diantaranya mengatakan bahwa pola makan yang tidak teratur dan stres menyebabkan ketidakteraturan siklus menstruasi. Hasil penelitian ini yaitu terdapat hubungan yang signifikan antara pola makan dengan siklus menstruasi (P = 0,014 < a 0,05) dan juga terdapat hubungan yang signifikan antara stres dengan siklus menstruasi (P = 0,004 < a 0,05) di SMA Muhammadiyah 4 Yogyakarta
Pengaruh Substitusi Minyak Kedelai Terhadap Daya Terima Mayonnaise yang Dihasilkan
Authors: Merry Astuti Yenni , Rukmini Ambar , Darmawan Eman , Nur Purwandhani Siti
Published: July 2024

Mayonnaise termasuk ke dalam salah satu bahan olahan pangan yang digunakan sebagai pelengkap atau dressing sauce dalam produk pangan lainnya Substitusi minyak kedelai dalam pembuatn mayonnaise menjadi salah satu cara memperbaiki sifat fisik pada mayonnaise. Tujuan penelitian ini adalah mengetahui pengaruh substitusi minyak kedelai terhadap daya terima, sifat fisik mayonnaise yang dihasilkan dan mengetahui persen substitusi minyak kedelai untuk mendapatkan mayonnaise yang dapat diterima dan komposisi kimia pada daya terima terbaik. Rancangan percobaan yang digunakan adalah Rancangan Acak Lengkap (RAL) satu faktor dengan substitusi minyak kedelai 0%, 20%, 40%, 60%, 80%. Data yang diperoleh kemudian dilakukan uji ANOVA, jika terdapat beda nyata dilanjutkan dengan Uji Duncan Multiple Range Test (DMRT) pada taraf signifikansi 5%. Hasil penelitian menunjukkan viskositas mayonnaise mengalami
penurunan seiring dengan substitusi minyak kedelai   dan nilai kestabilan emulsi

mayonnaise tidak ada beda nyata antar perlakuan. Uji organoleptik terhadap hedonik kesukaan terhadap warna dan aroma semakin meningkat tetapi rasa, kekentalan, dan kesukaan keseluruhan mengalamin penurunan/semakin rendah. Mayonnaise substitusi
minyak kedelai yang dapat diterima konsumen yaitu pada perlakuan perbandingan minyak sawit dan minyak kedelai 60% : 40% dengan nilai rerata 5,53 (agak suka).
Exploring Agile Methodology in Developing a Web-Based Result Computation and Transcript System: A Case Study of Federal Polytechnic Ukana
Authors: Esang Mfon Okpu , Johnson Ekemini Anietie , Attai Kingsley , Inyangetoh Jude Alphonsus , Dan Eduediuyai Ekerette , Okonny Kitoye Ebire , Bardi Ifeanyi , Bassey Aniefiok , John Anietie
Published: July 2024

In today's rapidly changing technological landscape, there is a great demand for efficient, adaptable, and responsive software development methodologies. This article examines how agile methodology was used in practice to create a web-based transcript and result computation system for Polytechnic Ukana. Agile methodology, which is renowned for its incremental and iterative approach, was used to increase flexibility, foster better teamwork, and produce a workable product on schedule. The article describes the goals and requirements of the project, including how Scrum was chosen as the agile framework and what stages it went through in implementation. Along with the roles and responsibilities of the development team, the planning, execution, and review processes for sprints are highlighted. The team demonstrated flexibility in responding to evolving needs, effective problem-solving, and sustained stakeholder engagement through a sequence of sprint cycles. The system was deployed on schedule, fulfilling all requirements and substantially boosting the accuracy and efficiency of the institution's transcript generation and result computation. This is proof that the project was successful. This case study provides a useful manual for implementing agile approaches for comparable educational software development projects.
Information and Communication Technology (ICT) as a Catalyst for Women Development in Africa
Authors: Abodunde Josephine
Published: July 2024

The paper examines the opportunities information and communication technology presents for women in Africa. No doubt that information now flows to African women with less distortion; it equally provides access to same information as their male counterpart on the continent. ICT has proven to create and re-create new opportunities by expanding information horizon and educational thereby making communication more flexible and accessible. Data for this paper came from secondary sources while it adopted the strategic model as its theoretical framework and its core argument is that beyond the opportunity presented by ICT, women must tap into its full advantage. It was discovered that the gap between men and women in terms of access to development-oriented information has been drastically reduced, as such women, voice their opinions, demand for their rights and have more control over their destiny cannot be said to be hidden by the men. ICT today has proven to be a veritable tool in transforming socio-economic and political life globally, African women inclusive. Findings shows that ICT is a Veritable tool for empowering women of all status The conclusion of the paper is that African women now have an opportunity in ICT to maximize their potentials for the overall development of the continent. The paper however recommends among other things that to mitigate further economic marginalization women must wholly embrace all the opportunities presented by ICT.