bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of bulk and sequential sampling methodologies on mammoth tooth enamel and their implications in paleoenvironmental reconstructions
Authors: Liu Zuorui , Prendergast Amy , Drysdale Russell , May Jan-Hendrik
Published: September 2022

Abstract. Mammoth teeth have been widely investigated using stable-isotopic analysis
for paleoenvironmental and paleoecological reconstructions due to their
large size and frequent discoveries. Many past investigations sampled the
tooth enamel with the “bulk” method, which involves drilling one sample from
the occlusal surface to the root for each tooth. Some of the more recent
studies applied the “sequential” method, with a sequence of samples drilled
following the dominant enamel growth direction to produce a time series of
isotopic oscillations that reflects high-resolution environmental changes, as
well as changes in mammoth dietary behavior. Although both the bulk and
mean sequential δ18O values are expected to represent the
averaged signal over the time of tooth formation, it is uncertain whether
their paleoenvironmental records were formed during similar periods of time.
In this study, we applied both sampling methods (sequential drilling first
followed by a thin layer of bulk drilling) on the same enamel ridges of
multiple mammoth teeth and compared their respective δ18O
values. The results indicated that, in most enamel ridges, the bulk samples
have more negative δ18O values compared to the average
sequential values, and some of the bulk values even fall outside the range
of sequential values. The most likely explanation for the differences is the
structure and formation stages of enamel that caused uneven distributions of
different seasons recorded in the samples. This finding provides insights
into current limitations of the two sampling methods and the applicability
of cross-method data comparison from past studies.
Ambivalent Modernity and Exoticism: Japanese Doll-Like Women in Pierre Loti’s Madame Chrysanthème and Tanizaki Jun'ichirō’s Tade kū mushi
Authors: Watanabe Sadahisa
Published: September 2022

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Shizu no odamaki or "The Thread from the Spool": Male Same-Sex Love and the Warrior Ethos in a Nineteenth-Century Historical Tale
Authors: Durante Daniele
Published: September 2022

Shizu no odamaki賤のおだまき(trans. The Thread From the Spool), a work of fiction composed presumably in the first half of the nineteenth century by an anonymous author, tells the novelized account of the lives and love story of two historical Japanese bushi 武士 or “warriors,” respectively named Yoshida Ōkura Kiyoie 吉田大蔵清家 (c. 1575-1599) and Hirata Sangorō Munetsugu 平田三五郎宗次 (c. 1585-1599). The two fighters lived in the Warring States period (Sengoku jidai戦国時代, 1467-1600) and died in combat during the “disturbance of Shōnai district” (Shōnai no ran庄内の乱, 1599-1600), one of the many conflicts that took place in this age of constant bloodshed. In presenting their fictionalized biography, Shizu no odamaki operates on two intertwining levels: one romantic, providing an idealized narration of the protagonists’ tie based on the so-called “Way of the Youth” (Wakashudō若衆道), the relationship between an adult man and an adolescent male, and of Sangorō’s juvenile beauty, and one ethical, depicting the characters’ feelings as a powerful catalyzer that assists them in their pursuit of the “Way of the Warrior” (Bushidō武士道). The two Ways, of male same-sex love and combat, thereby support each other in a virtuous circle. In proving the connection between Kiyoie and Sangorō’s sentiments and their commendable behavior as soldiers, the text pursues a didactic end by indicating their amorous and martial deeds as an authoritative example for the contemporaneous reader to emulate.In the following I provide an annotated translation of Shizu no odamaki. To prepare readers for the text, I offer in the next sections an overview of the lives of the historical Sangorō and Kiyoie figures as well as information about the records from which the narrative draws inspiration. Second, I present an analysis of the main coeval notions and social practices that the title invokes to conceptualize and portray the romantic relation between the two characters. Finally, I insert an outline of the diverging, and often conflicting, ways the narration was received and reinterpreted in the first decades of the Meiji era.
Contributors
Authors: Nara Hiroshi
Published: September 2022

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Learn Japanese Online: Elementary
Authors: Matsui Hisae
Published: September 2022

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Yamamba: In Search of the Japanese Mountain Witch
Authors: Shouse Ji
Published: September 2022

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"The Thread from the Spool" English translation of "Shizu no odamaki"
Authors: Durante Daniele
Published: September 2022

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Pengembangan Potensi Belimbing Wuluh Menjadi Dodol Untuk Pemberdayaan Masyarakat Di Desa Cot Girek Kandang Lhokseumawe
Authors: Rizka Nurlaila
Published: September 2022

Peningkatan kapasitas dan kualitas hidup bagi wanita dalam mengembangkan kemampuan dan potensi yang dimilikinya secara mandiri dengan memiliki keterampilan dan keahlian dalam mengatasi masalah yang dihadapinya melalui penyuluhan, pelatihan dan bahkan praktek langsung untuk membantu menumbuhkan serta meningkatkan intensi berwirausaha pada masyarakat. Belimbing wuluh memiliki rasa asam dan aroma yang khas sehingga sering digunakan dalam masakan dan juga berfungsi sebagai antioksidan karena adanya vitamin A, C dan E. Pemanfaatan dan pengembangan buah belimbing wuluh belum dilakukan secara optimal karena nilai jual yang masih rendah dan tidak diimbangi dengan potensi yang dimiliki buah belimbing wuluh. Tujuan kegiatan pengabdian kepada masyarakat ini untuk meningkatkan pengetahuan dan ketrampilan ibu-ibu dalam membuat dodol dari belimbing wuluh. Kegiatan yang dilakukan adalah pelatihan tentang pembuatan dodol dari belimbing wuluh dan melakukan penyebaran kuisioner awal dan akhir sosialisasi, dimana terjadi peningkatan pengetahuan mitra tentang pembuatan dodol.
The existence and uniqueness of solutions of a nonlinear toxin-dependent size-structured population model
Authors: Li Yan , Huang Qihua
Published: September 2022

In this paper, we study a toxin-mediated size-structured population model with nonlinear reproduction, growth, and mortality rates. By using the characteristic method and the contraction mapping argument, we establish the existence-uniqueness of solutions to the model. We also prove the continuous dependence of solutions on initial conditions.
Participación en la gestión educativa como vigencia de los derechos humanos
Authors: Yaguna Guerra Janeca Paola , Yaguna Guerra Maria Esther , Caicedo Manjarres Cielo Rocio
Published: September 2022

Colombia emprendió un proceso de reforma institucional a principios de la década de los noventa, dada la convocatoria a una Asamblea Nacional Constituyente, con la cual se aprobó una nueva Constitución Política, bajo una concepción de Estado Social de Derecho, pero con un sesgo marcado bajo una corriente neoliberal. El trabajo tiene como objetivo describir la participación y la educación como derechos humanos en Colombia. Se desarrolló una investigación analítica documental, fundamentada en el método deductivo y hermenéutico. Los hallazgos demuestran: 1) La participación ciudadana tiene un rol significativo en el proceso de democratización de la Educación; mediante la participación comunitaria como elemento clave en la gestión educativa; 2) La Educación es un derecho con el que se pretende garantizar la inclusión social, no solo en los procesos de formación sino en la formulación y ejecución de planes educativos. Se concluye: Existencia de una vasta normativa que garantiza el derecho a la participación y la educación como derechos humanos.
Transferencias locales y su relación con la alternancia política en México
Authors: Soto Zazueta Irvin Mikhail , Chávez Piña Giovani Hasael
Published: September 2022

La alternancia política representa la expresión ciudadana respecto a la aprobación del gobierno y obliga al gobernante a trabajar por el bienestar de la población, para demostrar que su partido tiene la capacidad para continuar en el poder. En este trabajo, se analiza el efecto de la asignación de transferencias locales (públicas y privadas) sobre la probabilidad de alternancia partidista en los municipios mexicanos. Con el objeto de determinar su eficacia como medio de control político-clientelar y como factor determinante de la permanencia de los partidos en el poder. Se especifica una ecuación con variable dependiente discreta no dicotómica, por su naturaleza utilizamos un modelo econométrico estimado con un Logit Ordenado. Los resultados muestran que en los municipios que han experimentado menos de tres alternancias en su historia, las transferencias privadas son eficientes en mantener el poder, mientras que la provisión de bienes públicos gana eficiencia para evitar la alternancia en municipios con tres o más alternancias. Se concluye que la mejor estrategia de asignación para permanecer gobernando se basará en la rentabilidad electoral de cada tipo de transferencias. Una vez la competencia y la alternancia política se consoliden, serán las transferencias públicas de beneficio generalizado las de mayor impacto electoral.
Responsabilidad Social Empresarial y percepción de los clientes de los Bancos Comerciales en Perú
Authors: Vilca Tantapoma Manuel Eduardo , Vilca Horna Nelly Melissa , Vilca Horna Ana Lucía , Armas Chang Mirtha Zulema
Published: September 2022

Esta investigación tuvo como objetivo determinar la relación directa entre la Responsabilidad Social Empresarial con la percepción de los clientes de los bancos comerciales en Perú; para ello, se identificaron factores que se relacionan con cada una de las variables. El diseño fue no experimental de tipo transversal – correlacional, se utilizó la técnica de la encuesta con su instrumento el cuestionario, dónde se aplicó un muestreo probabilístico de tipo aleatorio simple representado por 385 clientes de los bancos comerciales. Asimismo, se utilizó el análisis de confiabilidad de la escala mediante la estimación del Alpha de Cronbach y el chi-cuadrado que permitió comprobar la hipótesis que se planteó. Los resultados permitieron identificar que 77.14% de los clientes encuestados considera que si un banco comercial realiza actividades de RSE mejora su imagen institucional. Se concluyó que la Responsabilidad Social Empresarial tiene una relación directa en la percepción de los clientes de los bancos comerciales en Perú.
Gestión tutorial y liderazgo personal en tiempos de COVID-19 para estudiantes de educación universitaria
Authors: Huancaya De Salinas Aquila Priscila Montañez , Hilares Soria María Salome , Arainga Blas Eusebio , Roca Avila Yovana Connie
Published: September 2022

El presente artículo tiene por objetivo determinar la influencia la gestión de tutoría para el liderazgo personal y propósito de vida en tiempos de COVID 19 de estudiantes de educación universitaria. La investigación por su naturaleza corresponde al enfoque de investigación cuantitativa, de diseño con pre prueba - pos prueba con grupos experimentales y grupos de control; se ha experimentado el programa tutorial; para observar el comportamiento de la variable dependiente mediante la aplicación de una Escala de Apreciación Descriptiva o EAD de chequeo. Los resultados dan cuenta de diferencias significativas en las medidas de tendencia central del grupo experimental y el grupo control. Se concluye que la gestión de tutoría influye positivamente para el liderazgo personal y propósito de vida en tiempos de COVID 19 de estudiantes de educación universitaria.
Gobierno digital y modernización en entidades públicas peruanas: revisión sistemática de literatura
Authors: Salirrosas Navarro Liz Sobeida , Guerra Chacón Alfonzo Mauro , Tuesta Panduro Juan Alfredo , Álvarez Becerra Rina
Published: September 2022

En el contexto actual de pandemia el modelo de Gobierno Digital ha sido impulsado por diferentes Estados como una estrategia para incrementar la eficacia y eficiencia, facilitar ciertas operaciones, elevar la transparencia, economizar tiempo e inversión en función del Gobierno a los múltiples usuarios. A partir de la importancia que el Gobierno Digital tiene para muchos países, incluido Perú, es establecer qué aspectos son tomados, para la modernización de las instituciones públicas, para su análisis y reflexión. En función a esto, el objetivo de este artículo es analizar las variables e indicadores asumidos en la literatura científica en el periodo de 2018 a 2022 para medir el Gobierno Electrónico y la modernización en las instituciones públicas. Los resultados indican que existe relación entre el Gobierno Digital, Entidades Públicas y Modernización. Se evidencia que en la sociedad existe consenso, al concebir que las tecnologías de información y comunicación estén relacionadas de manera directa con el Gobierno Digital y Modernización de las Entidades Públicas. Se debe reforzar la preparación del empleado y del ciudadano para que puedan apropiarse del conocimiento necesario para darle un uso apropiado de las bondades que le ofrece el Gobierno Digital en las entidades públicas.
El desencuentro entre el público y el arte contemporáneo: Indicios de una transición cultural fallida en España
Authors: López-Raso Pablo
Published: September 2022

En una sociedad de la información que se sirve masivamente de las imágenes, observamos cómo paradójicamente aquellas que han sido creadas por artistas actuales producen generalmente incomprensión o incluso rechazo. Buena parte del público español fracasa al intentar interpretar unas imágenes codificadas por un arte de naturaleza experimental. El desinterés por la actualidad creativa que se percibe en España no debe ser ignorado, pues con el tiempo podría provocar un distanciamiento cultural de la Europa de su entorno, invitando a pensar que la transición política que el país experimentó tras la dictadura no ha tenido similar relevancia en lo cultural. Tres, son en nuestra opinión, las principales causas del problema de la recepción del arte contemporáneo en España: La gradual desaparición de las artes y humanidades en la enseñanza, la complejidad de su discurso intelectualizado por parte de cierta mediación cultural, así como la imagen excéntrica y banal que se proyecta alrededor de este tipo de manifestaciones desde numerosos medios de comunicación. Creemos que un análisis profundo de estos tres factores puede revelar un diagnóstico que ayude a establecer los medios necesarios para mejorar esta indeseada situación cultural en España.
Pengaruh Pembelajaran Daring Terhadap Motivasi Belajar Siswa Pada Mata Pelajaran Fisika
Authors: NURUL AINI  , NOVA SUSANTI
Published: September 2022

Penelitian ini membahas tentang motivasi belajar siswa terhadap pembelajaran daring. Motivasi belajar sangat penting untuk membuat situasi kondusif dalam mencapai tujuan pembelajaran yang diinginkan. Dengan adanya pendidikan kita dapat mengenal berbagai macam ilmu pengetahuan baik dari segi akademik maupun non akademik. Untuk menyusun jurnal ini, penulis melakukan penelitian dengan menggunakan google form yang berupa kuesioner yang dibagikan kepada siswa siswi kelas XI Mia 1 di MAN 1 Muaro Jambi, serta menggunakan google scholar untuk mencari referensi jurnal yang akan digunakan penulis. Pembelajaran daring merupakan pembelajaran yang dilakukan secara online, memakai pelaksanaan pembelajaran juga jejaring sosial. Pembelajaran daring adalah pembelajaran yang dilakukan tanpa melakukan tatap muka, tetapi melalui platform yang sudah tersedia. Dari hasil penelitian dengan menggunakan google form didapatkan hasil bahwa terdapat pengaruh pembelajaran daring terhadap motivasi belajar siswa tersebut, dan siswa siswi kelas XI Mia 1 di MAN 1 Muaro Jambi lebih dominan tidak setuju atau tidak semangat pada saat melakukan pembelajaran yang dilakukan secara daring pada mata pelajaran fisika.
Analisis Keterampilan Problem Solving Mahasiswa Jurusan Teknik Industri di Kota Bandung pada Materi Listrik Dinamis
Authors: Nurhuda Tiara , Abdul Muluk Raden Kiki , Rizkiah Riza
Published: September 2022

Problem solving dipilih sebagai tujuan utama pembelajaran di bidang sains dan teknik. Sebagai tujuan utama, problem solving dalam ilmu keteknikan menjadi gambaran keberhasilan dalam sains dan teknik yang dilakukan oleh setiap Negara. Di Indonesia, sudah diambil kebijakan untuk mendukung tujuan ini walaupun tidak dijelaskan secara gamblang. Untuk mengetahui keberhasilan pembelajaran fisika di jurusan keteknikan di Kota Bandung, maka peneliti merasa perlu untuk menganalisis keterampilan problem solving di Kota Bandung sebelum memberikan solusi konkret atas permasalahan yang dihadapi. Penelitian ini bertujuan untuk memberikan gambaran keterampilan problem solving mahasiswa teknik di Kota Bandung. Desain penelitian yang digunakan adalah penelitian kuantitatif yang menggunakan metode deskriptif (deskriptif-kuantitatif) yaitu penelitian yang gambarannya menggunakan ukuran, jumlah atau frekuensi. Penelitian dilakukan pada mahasiswa tingkat pertama di beberapa Universitas di kota Bandung, teknik pengambilan sample menggunakan cluster random sampling. Hasil penelitian diperoleheh rata-rata kriteria dari keseluruhan aspek problem solving, yaitu kriteria sangat rendah 21,5%, kriteria rendah 31,5%, kriteria cukup 23,67%, kriteria baik 15,83% dan kriteria sangat baik 7,5%.
The surrounding vehicles behavior prediction for intelligent vehicles based on Att-BiLSTM
Authors: Gao Yunqing , Zhu Juping , Gao Hongbo ,   Department of Automation, University of Science and Technology of China, Hefei 230022, China,   Institute of Advanced Technology, University of Science and Technology of China, Hefei 230088, China
Published: September 2022

A surrounding vehicles behavior prediction method was presented for intelligent vehicles. The surrounding vehicles’ behavior is hard to predict since the significant uncertainty of vehicle driving and environmental changes. This method adopts bidirectional long short-term memory (BiLSTM) model combined with an encoder to ensure the memory of long-time series training. By constructing an attention mechanism based on BiLSTM, we consider the importance of different information which could guarantee the encoder’s memory under long sequence. The designed attention-bidirectional LSTM (Att-BiLSTM) model is adopted to ensure the surrounding vehicles’ prediction accuracy and effectiveness.
Comprehensive bioinformatic analysis of key genes and signaling pathways in glioma
Authors: Zhang Xiaoming , Jiang Mengyuan , Tang Shenfeng , Niu Chaoshi , Hu Shanshan ,   Department of Neurosurgery, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China,   Anhui Key Laboratory of Brain Function and Diseases, Hefei 230001, China
Published: September 2022

The identification of specific survival-related differentially expressed genes (DEGs) is a method for uncovering therapeutic approaches for various cancers, including glioma. However, the key target genes associated with the occurrence and development of gliomas remain unknown. In this study, we performed bioinformatics analysis on 17 GSE datasets and identified DEGs correlated with glioma. A total of 74 mutual-DEGs with downregulated expression in gliomas compared with that in normal brain tissues were found in 17 datasets. These DEGs were related to GABAergic synaptic transmission, chloride transmembrane transport, glutamate secretion, and gamma-aminobutyric acid signaling pathway. Gamma-aminobutyric acid type A receptor subunit gamma 2 (GABRG2) was identified as a hub gene in the protein-protein interaction network. GABRG2 exhibited lower expression in IDH wild-type astrocytoma than that in IDH mutant astrocytoma and indicated poor prognosis in glioma patients. GABRG2 may contribute to the progression of glioma by affecting GABA receptor-related pathways and is a potential biomarker for the diagnosis and treatment of glioma.
IITZ-01 activates NLRP3 inflammasome by inducing mitochondrial damage
Authors: Hu Wenxin , Jiang Wei ,   The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China
Published: September 2022

NLRP3 inflammasome can be activated by a variety of pathogen activators (including components of bacteria, viruses and fungi) or “danger signals” (including abnormal metabolites and environmental components), so its activation mechanism is extremely complex. IITZ-01 is a lysosomotropic molecule that can disrupt lysosomal functions. We found that IITZ-01 can activate inflammasome at a low concentration. Then, we determined that IITZ-01 is a specific activator of NLRP3 inflammasome through inflammasome stimulation, ELISA, Western blot and other experiments. Mechanistically, NLRP3 inflammasome activation induced by IITZ-01 is independent of direct binding and ion flow but dependent on mitochondrial damage and mROS accumulation. This study suggests that a lysosomotropic compound can activate NLRP3 inflammasome by impairing mitochondrial functions.
Gross Profit Margin, Return On Assets dan Return On Equity Terhadap Harga Saham (Studi pada Perusahaan Industri Barang Konsumsi yang Terdaftar di Bursa Efek Indonesia)
Authors: Lailiyah Elliv Hidayatul , Julianto Baron , Hayat Ardiansyah Ahsanul
Published: September 2022

Penelitian ini bertujuan untuk mengetahui faktor fundamental yaitu Gross profit Margin, Return On Asset, dan Return On Equity berpengaruh terhadap harga saham. Penelitian ini dilakukan pada perusahaan Industri barang konsumsi yang terdaftar di Bursa Efek Indonesia periode 2018-2020. Penelitian ini menggunakan purposive sampling dengan sampel sebanyak 48 perusahaan dengan data observasi sebesar 142 data. Pendekatan yang digunakan untuk menganalisis data adalah metode kuantitatif. Alat analisis yang digunakan dalam penelitian ini adalah uji regresi linear berganda dengan bantuan program komputer SPSS. Berdasarkan Penelitian yang telah dilakukan, maka hasil dari penelitian ini adalah GPM berpengaruh positif terhadap harga saham. ROA tidak berpengaruh terhadap harga saham. ROE berpengaruh positif terhadap harga saham.
Kontribusi Pajak Daerah Dan Retribusi Daerah Terhadap Pendapatan Asli Daerah Di Provinsi Papua Periode 2014-2021
Authors: Nusa Yahya , Panggalo Ludia
Published: September 2022

Penelitian ini bertujuan untuk menganalisis Pengaruh Kontribusi Pajak Daerah dan Retribusi Daerah terhadap Pendapatan Asli Daerah di Provinsi Papua periode 2014-2021. Penelitian ini menggunakan alat analisis Linear berganda. Hasil penelitian menunjukan bahwa secara terpisah bahwa Pajak daerah berpengaruh positif dan signifikan terhadap Pendapatan Asli Daerah, sedangkan Retribusi Daerah berpengaruh positif dan tidak signifikan terhadap Pendapatan Asli daerah. Dan secara bersamaan menunjukan bahwa pajak daerah dan retribusi daerah berpengaruh positif dan signifikan terhadap Pendapatan Asli daerah di provinsi Papua periode 2014-2021
Strategi Peningkatan Pendapatan Asli Daerah (PAD) Tempat Pelelangan Ikan (TPI) Pomako Kabupaten Mimika
Authors: Nusa Yahya , Berkat Yermias J
Published: September 2022

This study aims to increase the Fisheries sector's Regional Native Income (PAD) from the Pomako Fish Auction Place (TPI). The method used is descriptive. Analysis tools using SWOT analysis is the systematic identification of various factors to formulate a company's strategy based on maximizing strengths and opportunities and minimizing weaknesses and threats. The results of this study show that the ST strategy is produced or supports verified strategies in the form of socialization, enforcement of PERDA and PERKADA as well as the formation of an integrated team
Identifikasi Sektor Ekonomi Strategis Penunjang Pertumbuhan Ekonomi (Pendekatan Analisis Sektor Basis)
Authors: Manduapessy Rulan , Ola Fransiska Triyanti
Published: September 2022

Penelitian ini bertujuan untuk mengetahui sektor-sektor ekonomi yang strategis sebagai penunjang pertumbuhan ekonomi di Kabupaten Mimika. Dalam mencapai tujuan yang dimaksud, maka metode penelitian yang digunakan adalah metode penelitian deskriptif. Untuk mengetahui pertumbuhan ekonomi Kabupaten Mimika Tahun 2010-2017 dan sektor-sektor ekonomi yang strategis sebagai penunjang pertumbuhan ekonomi di Kabupaten Mimika, maka instrumen analisis data yang digunakan dalam penelitian ini adalah analisis Location Quetient (LQ), analisis Shift Share dan analisis Klassen Typology. Selama kurun waktu tahun penelitian, pertumbuhan ekonomi Kabupaten Mimika menghasilkan perubahan nilai tambah Shift Share yang positif sebesar 47.854,64 dan memiliki dua sektor ekonomi yang strategis sebagai penunjang pertumbuhan ekonomi Kabupaten Mimika. Sektor-sektor ekonomi tersebut ialah sektor pertanian, kehutanan dan perikanan, terutama pada sub sektor tanaman pangan dan sub sektor perikanan laut yang mendomilisi sektor perikanan; dan sektor ekonomi perdagangan besar dan eceran, reparasi mobil dan sepeda motor yang didukung dengan penerbitan surat ijin usaha perdagangan sebanyak 2.297 dan tercatat sebanyak 844 SITU yang dibuat oleh Dinas Perindustrian dan Perdagangan. Lajunya kegiatan perdagangan di Kabupaten Mimika berdampak baik untuk meningkatkan pertumbuhan ekonomi di Kabupaten Mimika
A Review on anticancer potential of Nitric Oxide
Authors: Hadi Faheem , Maqbool Tahir , Muhammad Tahir , Akhtar Shabana , Rafiq Muhammad , Awan Sana Javed , Shakoori Tania Ahmad , Tayyeb Asima
Published: September 2022

Nitrous oxide (N2O; laughing gas) is clinically used as a safe anesthetic (dentistry, ambulance, childbirth) and is appreciated for its anti-anxiety effect. Nitrous oxide (N2O) is a free radical gas that performs various physiological and pathological processes in the body. NO is produced by different enzymatic pathways and plays a role in homeostasis. Over the past years, NO has emerged as a molecule of interest in many ailments including cancer. But its role in cancer is still controversy. It can display dose-dependent anticancer therapy on the one hand and induce pro-cancer properties on the other hand. But as compared to conventional treatments, NO proved better tumor cell resistance. This review mentions the dichotomous nature of NO that may encourage future research assessing the role of NO in cancer prevention and treatment either as a single agent or in combination with other antineoplastic compounds.
Clinical evaluation and prevalence of hypertension in different areas of Pakistan Authors
Authors: Saleem Iqra , Said Muhammad Soaib , ullah Izhar , Hashmi Asif Mehmood , Hussain Abid , Rehman Saif ur , Suliman Nazir
Published: September 2022

Background: Hypertension is defined as a sustained systolic blood pressure greater than 140 mm Hg or sustained diastolic blood pressure greater than 90mm Hg. Hypertension occurs due to increased peripheral vascular arteriolar smooth muscle tone which leads to increased arteriolar resistance and reduced capacitance of the venous system. Primary objective: The purpose of this study was to determine the prevalence of hypertension in different areas of Pakistan and Azad Kashmir. Methods/Design: The survey was conducted among the population of different areas of Pakistan and Azad Kashmir, evaluating the dietary habits of the habitants, age factors, marital status, and job status. Setting: Data was taken from Rawalpindi Institute of Cardiology Pakistan. Participants: Data from 50 participants with different age groups was taken from the Rawalpindi Institute of Cardiology Pakistan. Intervention: Our 6th monthly survey showed that the major factors that exaggerate hypertension are, inappropriate diet, job stress, and workload, smoking in adults, age, and concomitant diseases. Primary Outcome Measures: The study is very effective for the community because it provides awareness about the emerging factors of hypertension and highlights the different ways of treating it both pharmacologically and non-pharmacologically. Results: The study revealed that people over 60 suffer more from hypertension. The disease was more common in working males than females. Smokers and patients suffering from other concomitant diseases were more prone to this disease. Conclusion: Studies help the community to modify their lifestyle to eradicate the disease. It will help in the early diagnosis of diseases and the appropriate therapy to enjoy a healthy and carefree lifestyle.
A Multidisciplinary Assessment on the dominance of contemporary western culture and EU civilization
Authors: EFE Ahmet
Published: September 2022

After the Cold War, the Clash of Civilizations thesis defended conflict between the West and Muslims. Samuel Huntington was instrumental in legitimizing and supporting the conflict between Islam and the West. According to this theory, conflicts will arise from cultural and religious reasons, not between ideologies and states. They will be the scene of clashes, especially between Western and Islamic civilizations. Although nation-states continue to be the main actors in the global system, their traditional sovereignty structures will erode, continuing their essential functions under the umbrella of civilization. While this theory is being discussed, statistics reveal that social, cultural, economic discrimination and intolerance, called Islamophobia, is being developed against Muslims, whose members are constantly increasing in western countries after the Cold War. This article examines the relationship between Islamophobia, rising in Europe, and the Clash of Civilizations thesis, with a multidisciplinary approach of theology, history, economics, and politics of assertions done in the Risale-i Nur Collection writings by Said Nursi.
Yöneticilerin Bakış Açısından Yatırım İzleme Ve Koordinasyon Başkanlıkları: Aydın Örneği
Authors: AYGÜL Ali , GENÇ Fatma Neval
Published: September 2022

2014 yılından itibaren yürürlükte olan 6360 sayılı yasa, büyükşehir belediyelerinin yapısında önemli değişiklikler meydana getirmiştir. Bununla birlikte yasa pekçok boyutu ile tartışılmaktadır. Tartışılan bu boyutlarından biri de Yatırım, İzleme, Koordinasyon Başkanlıklarıdır (YİKOB). Yasayla, büyükşehirlerde İl Özel İdareleri kaldırılarak çoğu görev ve yetkileri büyükşehir belediyelerine devredilmiş, büyükşehirlerde YİKOB kurulmuştur.

Bu çalışmada literatürde YİKOB’larla ilgili olarak tartışılan, eleştirilen konuların uygulamaya yansıması incelenmektedir. Bu çerçevede YİKOB’ların işleyişi uygulayıcıların bakış açısından değerlendirilmektedir. Bu kapsamda YİKOB’ların teşkilat yapısı, görev, yetki ve sorumlulukları; mali yapısı, denetimi Aydın YİKOB’da görevli yöneticilerle yapılan yarı yapılandırılmış görüşme formuyla değerlendirilmiştir. Aydın, 6360 sayılı kanunla büyükşehir statüsü kazanmıştır.

Yapılandırılmış görüşme formunda toplam 14 adet soru yer almaktadır. Görüşmeciler YİKOB’un Yatırım İzleme Müdürleridir. Görüşmelerden elde edilen nitel veriler içerik analizi ve betimsel analiz yöntemi ile yorumlanmıştır. Bu şekilde yöneticilerin YİKOB’lar ile ilgili görüşlerinin, mevcut veya ortaya çıkabilecek sorunların tespit edilmesi, sorunların çözümlerine dair önerilerin geliştirilmesi amaçlanmıştır.
GYNECOLOGICAL AND PSYCHOSOCIAL RISK FACTORS ASSOCIATED WITH OBESITY IN ADOLESCENT GIRLS
Authors:   Faculty of Rehabilitation and Allied Health Sciences (FRAHS) Riphah International University, Islamabad, Pakistan, Rauf Ammara , Riaz Huma ,   Faculty of Rehabilitation and Allied Health Sciences (FRAHS) Riphah International University, Islamabad, Pakistan, Nadeem Hadia ,   Faculty of Rehabilitation and Allied Health Sciences (FRAHS) Riphah International University, Islamabad, Pakistan
Published: September 2022

Background: There has been an increase in childhood and adolescent obesity worldwide, which affects the girls resulting low self-esteem and depression and diminishes health- related quality of life. The overweight and obese teenage girls are more likely to have gynaecologic and obstetric complications during adolescence and later in life. Objective: To determine gynaecological and psychosocial risk factors associated with obesity in adolescent girls. Methods: A cross sectional study conducted at schools and colleges of Islamabad and Rawalpindi with a sample size of n=99. The participants were divided into two groups of which n=25 were obese adolescents (cases) and n=74 were non-obese adolescents (controls). The Data collection was done based on self-structured questionnaire from adolescent females aged 10 to 19 years in cases with BMI >27.5kg/m2 in controls 18.5 to 23kg/m2. The study duration was 6 months from (October- 2020 to March- 2021). Study was conducted in various school and colleges of Islamabad and Rawalpindi. To determine the association odds ratio (OR) was calculated. Results: The mean age of the cases was 16.2±2.10 years and 14.78±1.82 years for controls. The BMI of cases was 29.38±1.97 kg/m2 and a control was 18.06±2.88 kg/m2. In gynaecological risk factors cases are more at risk to have excessive acne/pimple on face (Odds ratio: 3.484, p= 0.008), more likely to experience amenorrhea (OR: 4.504, p= 0.007) and more likely to have excessive facial/abdominal hair growth (OR: 3.600, p=0.014). For psychosocial risk factors the cases presented with a greater need/referral of a psychological evaluation (OR: 4.063, p=0.008) and feel social limitation or emotional disturbance (OR: 2.561, p=0.044). Conclusion: It was concluded that certain gynaecological and psychosocial determinants could be influenced by adolescent obesity leading to many complications and negative consequences on present and future health outcomes. Key words: adolescents, females, gynaecologic, obesity, overweight, quality of life
The Movement of Indonesia’s Foreign Exchange Rates and Other Macroeconomic Variables to Its Stock Market Volatility in a Pandemic Setting
Authors: Venessa Venessa , Yulfiswandi Yulfiswandi
Published: September 2022

This paper aims to examine the impact of foreign exchange rates on Indonesia’s composite stock index, the JKSE. To perfect the analysis, several other macroeconomic variables such as interest rates, oil prices, gold prices, as well as inflation rates were also added as proposed by preceding research. COVID-19 new infection cases were added as a moderating variable to test whether it can strengthen or weaken the correlation of each macroeconomic variable tested against the stock market. The parameter of this study is specifically focused on Indonesia to complete the lack of sufficient research conducted for the same topic and/or in the same setting. The study found all the macroeconomic variables tested in the analysis concurrently influence Indonesia’s stock market index. When each macroeconomic was tested separately, the test results found that although the direction of the impact varies, all the variables except for gold price were found to have a significant impact on the stock market in Indonesia. The moderating variable, COVID-19, was also found to have a notable influence on substantiating the impact of all the correlations tested except in moderating for exchange rates and oil price.
Pengaruh Pola Asuh Orang Tua Terhadap Kecerdasan Akademik Anak Usia 5-6 Tahun di Era Pandemi Covid 19
Authors: Suherni Asmanih , Mariyani Mariyani
Published: September 2022

Perilaku anak dalam mencapai tujuan yang diinginkan dipengaruhi bagaimana cara orang tua dalam mendidik, mengajar,dan mengembangkan perilakuanak.Pola asuh yang baik akan menjadikan anak memiliki pribadi yang baik, semangat dalam belajar dan memiliki prestasi yang cemerlang. mengetahui hubungan pola asuh orang tua dengan  ingkat kecerdasan akademik anak usia 5-6 tahun. penelitian ini menggunakan rancangan penelitian asosiatif. Sampel yang digunakan sebanyak 68 anak TK. Pengumpulan data menggunakan kuesioner dan lembar observasi. Data dianalisis melalui uji Chi-Square. Jumlahanak dengan pola asuh baik adalah sebanyak 40 orang (56%) dan anak dengan pola asuh kurang baik sebanyak 28 orang (41%). Jumlah anak dengan kecerdasan akademik kategori berkembang adalah sebanyak 39 orang (57%) dan jumlah anak dengan kategori kurang berkembang sebanyak 29 orang (43%). Ada hubungan antara pola asuh orang tua dengan kecerdasan akademik anak usia 5-6 tahun, dimana Hasil uji Chi-Square (X2) menunjukkan nilai p (0,000) < 0,05. Ada hubungan antara pola asuh orang tua dengan kecerdasan akademik anak usia 5-6 tahun. Kata kunci: pola asuh, kecerdasan akademik
Efektivitas Dzikir Dalam Mengurangi Tingkat Kecemasan Pasien Pre Operasi Sectio Caesarea di Ruang Instalasi Bedah Sentral RSUD Pasar Rebo
Authors: Octavia Lia , Jamiatun Jamiatun , Ifadah Erlin , Abdurrochim Abdurrochim
Published: September 2022

Sectiocaesarea adalah proses persalinan dengan cara pembedahan untuk mengeluarkan janin dengan cara membuat sayatan pada dinding abdomen dan uterus. Proses tindakan sectiocaesarea dapat menimbulkan masalah yang cukup kompleks baik secara fisik, psikologis, sosial, dan juga spiritual, khususnya kecemasan pasien yang meningkat. Sedangkan terapi non farmkologis meliputi teknik dzikir. Untuk mengetahui efektivitas dzikir dalam mengurangi tingkat kecemasan pada pasien preoperasi sectiocaesarea di ruang Instalasi Bedah Sentral RSUD Pasar Rebo Jakarta Timur. Penelitian ini merupakan penelitian kuantitatif dengan desain penelitian Preeksperimental desain, rancangan penelitian menggunakan One Group Pretest Posttest desain. Sebelum melaksanakan intervensi dilakukan observasi pertama (pretest). Kemudian di lakukan observasi kedua (posttest) setelah intervensi. Penentuan rumus sampel dilakukan dengan menggunakan rumus Federer yaitu : (n-1) X (t-1) ≥15, didapatkan hasil 16 sampel. Teknik pengumpulan data yang digunakan pada penelitian ini adalah data primer yang didapat dari hasil wawancara atau hasil pengisian kuesioner skala HARS yang dilakukan oleh peneliti. Hasil uji T berpasangan menghasilkan nilai α yang dapat dilihat pada kolom “Sig (2-tailed)”, didapatkan nilai p = 0,014, maka dapat disimpulkan bahwa ada perbedaan yang signifikan antara kecemasan sebelum berdzikir dengan kecemasan setelah berdzikir pasien preoperasi sectiocaesarea di ruang Instalasi Bedah Sentral RSUD Pasar Rebo Jakarta Timur. Dzikir yang berulang-ulang dibaca yang biasa dilakukan pasien, efektif untuk mengurangi tingkat kecemasan pasien preoperasi sectiocaesarea di ruang Instalasi Bedah Sentral RSUD Pasar Rebo, sehingga perawat diharapkan mau untuk menganjurkan dzikir tersebut kepada pasien.Kata Kunci : Terapi dzikir, tingkat kecemasan, pasien pre operasi sectiocaesarea .
Erratum to: «QUANTITATIVE CHARACTERISTICS OF SEISMIC GROUND OSCILLATIONS BY STRONG MOTION RECORDS ON THE EAST KAZAKHSTAN TERRITORY»
Authors: Mikhailova N. N. , Sokolov A. N. , Sokolova I. N.
Published: September 2022

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APPLICATION OF THE TEXT INTERFACE OF THE ANSYS FLUENT PROGRAM FOR SIMULATION OF THE THERMOPHYSICAL STATE OF A TYPICAL EXPERIMENTAL DEVICE
Authors: Kabdylkakov Ye. A. , Suraev A. S. , Irkimbekov R. A.
Published: September 2022

The paper is dedicated to development of log of the ANSYS FLUENT program text commands. Although this program has well-developed and easy-to use graphical interface, command logs allow to conduct the configurations of the solver, optimizing the process of calculation justification safety of reactor experiments conducted at the “Institute of Atomic Energy” Branch of the RSE “National Nuclear Center of the Republic of Kazakhstan” (IAE Branch RSE NNC RK). Command logs allows to control the command to save the ANSYS FLUENT program solver as code in a separate file, which can later be used for other calculations. Command log allows to save settings the ANSYS FLUENT program solver as program code in a separate file, which can later be redacted and used for other calculations. Also, this would enable improving the group work of employees above one project, facilitate the exchange process of solver parameters and promptly make amendments and corrections. In the framework of this work, a technique for constructing a command log was developed for modeling thermophysical state of experimental devices in reactor experiments. The developed technique was tested on the example of solving a thermophysical task with a typical ED.
Compromiso gástrico en la enfermedad injerto contra huésped aguda: presentación de un caso clínico
Authors: Chitussi Micaela , Bajo Juliana , Girotti Claudio
Published: September 2022

El trasplante de células hematopoyéticas constituye uno de los tratamientos más importantes para enfermedades hematológicas malignas y no malignas. Una de las complicaciones más frecuentes y graves del procedimiento es la enfermedad injerto contra huésped, siendo la principal causa de mortalidad. La enfermedad injerto contra huésped puede ser aguda o crónica y se diferencia por su presentación clínica. Ambas formas son importantes por su impacto sobre el pronóstico del paciente. El compromiso gastrointestinal agudo es generalmente el más grave y plantea desafíos diagnósticos y terapéuticos. El compromiso digestivo alto se encuentra particularmente subdiagnosticado, motivo por el cual presentamos un caso de enfermedad injerto contra huésped agudo con afectación gástrica.
Colitis isquémica y amiloidosis: un desafío diagnóstico
Authors: Benitez Florencia , Pontet Yéssica
Published: September 2022

La amiloidosis comprende un grupo heterogéneo de enfermedades infiltrativas caracterizadas por el depósito extracelular de fibrillas proteicas insolubles. El tubo digestivo puede afectarse en cualquier sector de forma directa o por infiltración del sistema nervioso autónomo. Los sectores más frecuentemente involucrados son el colon descendente y el sigmoides. El diagnóstico es histológico mediante tinción con Rojo Congo. La colitis isquémica es la patología isquémica más frecuente del tracto gastrointestinal. La mayoría de las veces es transitoria y reversible, siendo el colon izquierdo el sector involucrado con más frecuencia. Las manifestaciones clínicas son inespecíficas y dependen tanto del grado de isquemia como de los sitios afectados. La videocolonoscopía es considerada el patrón oro para el diagnóstico. La distribución topográfica de las lesiones suele ser territorial, segmentaria y parcheada, según los vasos ocluidos. La ausencia de hallazgos patognómicos para el diagnóstico de colitis isquémica hace difícil su determinación en el contexto de comorbilidades como la amiloidosis, ya que esta enfermedad puede tener la misma presentación clínica y endoscópica. La isquemia no sólo constituye uno de sus mecanismos fisiopatológicos de lesión intestinal, sino que también puede ser consecuencia de una afectación sistémica independiente de la infiltración colónica. Se describe y discute el caso de un paciente de 60 años con amiloidosis asociada a cadenas ligeras y debut de colitis, que se presenta con sangrado digestivo bajo y dolor abdominal. Debido al diagnóstico en diferido de amiloidosis colónica y sus características similares a la colitis isquémica, discernir entre ambos resultó un desafío diagnóstico.
Ensayos clínicos de no inferioridad
Authors: Pizarro Rodolfo
Published: September 2022

Los ensayos clínicos de no inferioridad se llevan a cabo ya que se considera que el tratamiento experimental no es mejor que el estándar sino que ofrece ventajas adicionales, tales como: menos efectos secundarios, mejor perfil metabólico, más fácil administración, menos controles y costos.
En memoria del profesor Osvaldo Manuel Tiscornia
Authors: Vaccaro María Inés , López Mignorance Fabiana
Published: September 2022

La noche del 11 de julio, a los 94 años, partió el profesor Osvaldo Manuel Tiscornia. Nos dejó su legado de ideas de incansable pensador, su pasión por el conocimiento, sus enseñanzas profesionales y sus consejos de vida. Lo recordaremos con mucho cariño, como uno de los grandes maestros de la Medicina, Profesor de la Cátedra de Anatomía, fue un excelente gastroenterólogo y científico. El Dr. Tiscornia creó y dirigió hasta su último día el Programa de Estudios Pancreáticos del Hospital de Clínicas de la Universidad de Buenos Aires. Allí, sus discípulos aprendimos mucho de sus innumerables aportes científicos y descubrimientos sobre la fisiopatología de las enfermedades pancreáticas. Osvaldo Tiscornia fue, por sobre todas las cosas, un médico sumamente humano, querido y admirado por sus discípulos y colegas. Lo extrañaremos.
Ekip Çalışması Algısının İç Girişimciliğe Etkisi: Hemşireler Üzerine Bir Araştırma
Authors: SOYSAL Abdullah , ÇAKIR Mehmet
Published: September 2022

Bu araştırmada, yoğun bakım hemşirelerinde ekip çalışması algısının iç girişimciliğe etkisinin olup olmadığını ortaya koymak amaçlanmıştır. Araştırma Kahramanmaraş Sütçü İmam Üniversitesi Sağlık Uygulama ve Araştırma Hastanesi ile Kahramanmaraş Necip Fazıl Şehir Hastanesinde çalışan yoğun bakım hemşireleri üzerinde uygulanmıştır. Toplam 176 yoğun bakım hemşiresinden anket yöntemi aracılığıyla toplanan veriler frekans analizi, bağımsız örneklem t- testi, ANOVA testi, korelasyon ve regresyon analizleri ile incelenmiştir. Araştırma sonunda elde edilen bulgulara göre ekip çalışması ile iç girişimcilik arasında pozitif yönlü zayıf fakat anlamlı bir ilişkinin olduğu saptanmıştır. Araştırmada katılımcıların ekip çalışması algısının iç girişimciliğe etkisi üzerinde pozitif yönlü ve anlamlı bir etkisinin olduğu tespit edilmiştir. Ayrıca demografik değişkenlerden sadece yaş değişkeni ile iç girişimcilik ölçeği arasında anlamlı bir farklılık olduğu sonucuna ulaşılmıştır.
Gay tourism in Manzanillo, Colima: push and pull development potential through Crompton model
Authors: Sosa Rodriguez Jesus Otoniel , Silvestre Campos María Adelaida , Coss Sandra , Ordoñez Pedro
Published: September 2022

Internationally, gay or LGBT tourism represents a potential market of 180 million people and an annual expense in the tourism industry of 200 billion dollars. In addition to this, gay tourism grows at a rate of 10.4% each year, more than double of conventional tourism.
Mexico is already taking some actions to take advantage of the opportunity represented by attracting this new type of market. However, Manzanillo has been a tourist destination that has not joined the actions carried out by the Ministry of Tourism to become a gay-friendly destination.
The objective of this study is to analyze the current situation in Manzanillo regarding gay tourism; to identify actions taken and the reasons why it has not yet developed. To this end, the research question is as follows: Why is Manzanillo not considered a gay-friendly destination and what strategies can be carried out to achieve it?
The question is answered through research carried out with a mixed approach methodology, the empirical method complemented by the method of analysis of surveys and interviews.
The responses received show that Manzanillo is not considered a gay-friendly destination because it does not have a tourist offer destined for this market segment, but despite this, it has the potential to become a pink destination.
Taking the above into account, five strategies were carried out as a proposal to diversify the tourist offer of Manzanillo with the creation of activities and establishments destined for gay tourists.