bluuebunny/crossref_metadata_2025 huggingface dataset:
DIRECT RENIN INHIBITORS IN ARTERIAL HYPERTENSION TREATMENT
Authors: Meretskyi Viktor , Meretska Iryna , Kulyanda Olena , Kamtoh Georges
Published: December 2017

High blood pressurewas the leading cause of death and disability-adjusted life years worldwide. Despite progress in treatment of hypertension, a number of people with uncontrolled or resistant hypertension increases. Hypertensive disorders are strongly linked with an overactive renin-angiotensin aldosterone system. The renin-angiotensin-aldosterone system has been a highly successful pharmacologic target, as the system is strongly implicated in the development of hypertension-related target organ damage.Inhibition of renin-angiotensin aldosterone system, using inhibitors of the angiotensin-converting enzyme or angiotensin II receptor blockers, is an effective way to intervene with the pathogenesis of arterial hypertension.Renin inhibitors block the renin-angiotensin aldosterone systemat the highest level, at its origin, and might thus offer a new exciting approach for pharmacotherapy of hypertension. Aliskiren, an octanamide, is the firstof a new class of completely non-peptide, low-molecular-weight, orally active transition-state renin inhibitors and only approved for the treatment of hypertension.summarizes the available data on the pharmacokinetic and pharmacodynamic properties of aliskiren and its clinical role for treatment of arterial hypertension.
Implementasi Model Pembelajaran Student Teams Achievement Division dan Team Assisted Individualization ditinjau dari Kemampuan Spasial Siswa
Authors: Kusuma Arie Purwa
Published: December 2017

The objectives of this research were to investigate the effect of the learning models on the learning achievement in Mathematics viewed from the spatial ability of the students. This research used the quasi-experimental research method with the factorial design of 3 x 3. Its population was all of the students in grade XI of State Senior High Schools of Wonosobo regency in Academic Year 2017/2018. The samples of the research were taken by using the cluster random sampling technique. They consisted of 326 students. The data of the research were analyzed by using the two-way analysis of variance with unbalanced cells.The results of the research are as follows.1) The cooperative learning model of the STAD type results in a better learning achievement in Mathematics than the cooperative learning model of the TAI type and the direct learning model and the cooperative learning model of the STAD type results in a better learning achievement in Mathematics than the conventional learning model.2) The learning achievement in Mathematics of the students with the high spatial ability was better than that of the students with the moderate and low spatial abilities, and the learning achievement in Mathematics of the students with the moderate spatial ability was better than that of the students with the low spatial ability. 3) There was an interaction the aforementioned learning models and the categories of the spatial ability on the learning achievement in Mathematics of the students.
PEMODELAN MATEMATIKA PREMI TUNGGAL BERSIH ASURANSI UNIT LINK SYARIAH
Authors: Supriadi Nanang
Published: December 2017

The exact risk factor can be managed by transferring the risk to the other party (in this case the insurance company). In this paper will be discussed more life insurance, as the development now there are types of insurance combined with investment, which is popular with the term Unit Link insurance. Unit link Syariah began to be launched as one of the fulfilment of the high needs of the community, the privilege of the product Unit of Islamic links is actually located in the elements of the laws in accordance with Islamic Syariah. The issues that will be discussed are how to get a single premium model of life insurance unit link Syariah with life insurance and investment fund allocation invested in investment product with a big interest rate of risk (financial approach) and investment product with the value of return maximum (actuarial approach). The resulting model is then implemented in case of examples by comparing the two approaches to see the shortcomings and advantages of Unit link lifetime life insurance when compared to life insurance. The result obtained from this research is the benefit obtained from Unit-linked sharia insurance on average will be greater if compared with life insurance for life, maximum benefit will be obtained Insurance Unit Link of sharia using actuarial approach compared to financial, but benefit with a relative financial approach more stable than actuarial approaches that tend to fluctuate.
Pengembangan Media Pembelajaran Matematika dengan Macromedia Flash
Authors: Masykur Rubhan , Nofrizal Nofrizal , Syazali Muhamad
Published: December 2017

The purpose of this research is to develop math learning media using Macromedia flash application program. The development procedure used is Borg and Gall procedure which has been modified by Sugiyono. The procedure used is limited to only 7 steps from 10 steps: potential and problem, information gathering, product design, design validation, design improvement, small and large scale test until product revision. This study produces a mathematics learning media that has been declared valid and fit to be used as a whole as a medium of learning by 3 Expert material who scored an average of 3.67 and 2 media experts who scored an average of 3.59 with each score the maximum of validity is 4. While the attractiveness test of instructional media is stated "Very Interesting" by small group test which gets average score 3,4 and big group test with average score 3,8 with each score maximize attractiveness is 4. So it can be concluded that the development of instructional media produced is considered feasible and can be used as a medium of mathematics learning.
Kemampuan Berpikir Kritis Matematis Berdasarkan Kecerdasan Multiple Intelligences
Authors: Mujib Mujib , Mardiyah Mardiyah
Published: December 2017

Based on the cognitive development of junior high school students began to be able to think formal, able to think the high level of mathematical thinking or high-level mathematical thinking, and mathematical thinking with a low order or low-level mathematical thinking). The research method used is descriptive qualitative. Taking the subject in this study is to use purposive sampling techniques. Being the subject of research is the students of SMP PGRI Class VII as much as 35 Bandar Lampung academic year 2017/2018. Data technique used is test method, questionnaire, observation, and interview. Data analysis is done descriptively qualitative. This research looks at mathematical thinking based on students' multiple intelligences. Students are Linguistic Intelligence, Logic-Mathematics and Spatial Intelligence. Each intelligence of multiple intelligences capable of reading the problem well, able to store information, images of different mathematical symbols. Being able to understand what to do, have ideas to math symbols. Students can make mathematical formulas clearly, able to differentiate, equate, integrate, classify between variables analyze, summarize, criticize, predict, compose, build, plan, discover, renew, ner, strengthen, beautify, compose. Students who have the tendency of intelligence Linguistic Intelligence how to translate keywords used word for word more compiled. Logical-Mathematical Intelligence. the methods used in solving mathematical problems are seen more structured results, and Intelligence Intelligences ways used with cultural patterns.
Pengembangan Blog Sebagai Media Pembelajaran Matematika
Authors: Nugroho Aji Arif , Putra Rizki Wahyu Yunian , Putra Fredi Ganda , Syazali Muhammad
Published: December 2017

Develop and Test the feasibility of media-based mathematics learning blog especially in the trigonometric material which becomes the purpose of research. This development research uses 7 stages from 10 stages of borg and gall method that are potential and problem, collecting preliminary data, product design, validation, revision, trial, product revision and mass production. Blog learning media developed with the help of adobe flash aimed at providing some animation. The assessment instrument used is a feasibility questionnaire by media experts, materials experts, and student feedback. The result of the research is 1) Based on validation of material expert evaluation, the average score of 4.65 is in the category of "Very Good". Assessment of media experts gives an average rating of 4.35 so that the assessment in the category of assessment of "Very Good". The assessment of linguists gives an average rating of 4.5 which is included in the "Excellent" rating. In addition, in a small-scale test of the students obtained a score of 4.23 on the criteria of "Very Good", and while tested large-scale average test score of students responses is 4.19 obtained "Good" criteria. Thus it is concluded that the learning media that have been developed are in a good category and can be used in learning especially Trigonometry material.
Los Habsburgo en el Río de la Plata: Gobernadores de capa y espada en el Buenos Aires colonial temprano
Authors: Trujillo Oscar Jose
Published: December 2017

El objeto de este artículo es analizar el proceso de militarización  del estilo de gobierno que se percibe en el contexto de la Gobernación del Río de la Plata, desde su creación en 1617 hasta fines del siglo XVII, cuando los Habsburgo dejaban paso a los Borbones. Se proponen como claves de ese proceso la descripción del perfil de esos gobernadores y el análisis de su correspondencia con el Consejo de Indias, comparados con el proceso de dotación y equipamiento militar de la ciudad. Desde los primeros tiempos del poblamiento y organización jurisdiccional del territorio, la cuestión militar fue decisiva a la hora de configurar la geopolítica de la Corona con respecto al espacio local.
Puertas y llaves. Reconfiguración de los vínculos entre gobernadores y vecinos en Buenos Aires a partir de las reformas borbónicas tempranas
Authors: Birocco Carlos María
Published: December 2017

Hasta la primera década del siglo XVIII, las relaciones de poder político se estructuraban en Buenos Aires en torno al vínculo entre el gobernador y un sector de los vecinos, compuesto por los miembros de una parentela local o por un conjunto de acólitos no emparentados entre sí. Eso generó enfrentamientos de facciones en el Cabildo, donde tendrían lugar la confrontación y negociación política. Pero desde 1715 la Corona confió la Gobernación del Río de la Plata a militares de prestigio que recibieron directivas para poner fin a la lucha facciosa. Uno de ellos, Bruno Mauricio de Zavala, intentaría someter al cabildo a través de la resignificación del empleo de teniente de gobernador, no sin generar la resistencia de sus integrantes.
Los nuevos gobernantes de la Monarquía borbónica o el mundo de relaciones y servicios de Bruno Mauricio de Zavala (1682-1736)
Authors: Guerrero Elecalde Rafael
Published: December 2017

El reinado de Felipe V supuso un momento de importantes cambios en la Monarquía hispánica. La aplicación de las primeras reformas también conllevó el cambio de las elites gobernantes, donde los colectivos periféricos fueron privilegiados por su especial lealtad a la causa borbónica durante la Guerra de Sucesión. Entre ellos, vascos y navarros fueron especialmente privilegiados, alcanzando las más cotas de poder, Así le sucedió a Bruno Mauricio de Zavala, que alcanzó los más altos cargos en la jerarquía militar y estuvo al frente de la gobernación de Buenos Aires. Familias, negocios, capitales, patrocinios, vínculos, servidumbres, contactos en la corte o servicio al rey fueron elementos fundamentales para conocer las formas de gobierno de la Monarquía de principios del siglo XVIII, lo que ayudará a desentrañar los fundamentos de la carrera del fundador de la ciudad de Montevideo como uno de los hombres principales de Felipe V.
Maternidades públicas y adopción legal en Córdoba, 1957-1974
Authors: Gentili Agostina
Published: December 2017

Este artículo reconstruye el modo en que las maternidades públicas de la ciudad de Córdoba entregaban niños en adopción en los años sesenta. Para ello, se recurre a la documentación enviada a las autoridades judiciales para legalizar aquellos actos de entrega: un conjunto de expedientes de los juzgados de menores sometidos a operaciones de cuantificación, reducción de la escala de observación y contextualización. Focalizándose en el juego de ponderaciones del que eran objeto el arbitrio asistencial y la convalidación judicial de esas entregas, se sostiene que esas experiencias de interacción permiten comprender rasgos emblemáticos del proceso de institucionalización de la adopción.
Raúl Scalabrini Ortiz y su relación con la Unión Cívica Radical
Authors: Rubio García Gonzalo
Published: December 2017

Desde sus primeros escritos, Raúl Scalabrini Ortiz guardó una relación ambivalente con la Unión Cívica Radical (UCR) y en especial con Hipólito Yrigoyen. El artículo analiza las críticas y reivindicaciones que dicho autor hizo hacia el expresidente radical y su partido, teniendo en cuenta el contexto de época en que realizó sus observaciones y la incidencia que tuvo la llegada del peronismo en sus publicaciones. Además se tuvieron en cuenta las posturas nacionalistas de Scalabrini y el fin ideológico que perseguía su relato, siendo esta una de las explicaciones que se argumentó para dar cuenta del cambio de postura frente a la figura de Yrigoyen.
Pérdida de complejidad en la ciudad compacta del mercado inmobiliario
Authors: Giglio Luciana , Freaza Nadia , Aón Laura
Published: December 2017

El presente artículo parte de la idea central de la tesis de Salvador Rueda, que establece que una ciudad sustentable es una ciudad compacta, compleja y diversa en usos, espacios y actividades. Desde esta premisa, el trabajo cuestiona cómo las políticas urbanas y las lógicas de los actores inmobiliarios influyen sobre los procesos de densificación del parque habitacional en áreas centrales urbanas. Cuando dichos procesos carecen de pautas normativas que garanticen un desarrollo equilibrado en los tipos de vivienda, esto repercute sobre la distribución de la población en el territorio y condiciona su acceso a los servicios y equipamientos básicos urbanos. Para dar marco al debate se tomó el caso del área central de La Plata entre 2004 y 2014, indagando en las transformaciones del parque habitacional y las lógicas de construcción a partir del concepto de complejidad y diversidad.
Mauricio Onetto Pavez (2017). Temblores de tierra en el jardín del Edén. Desastre, memoria e identidad. Chile, siglos XVI-XVIII
Authors: López Calvo Melina
Published: December 2017

Reseña bibliográfica: Mauricio Onetto Pavez (2017). Temblores de tierra en el jardín del Edén. Desastre, memoria e identidad. Chile, siglos XVI-XVIII.

Ediciones de la Dirección de Bibliotecas, Archivos y Museos. 2017. Santiago, Chile. El patrimonio de Chile. Centro de investigaciones Diego Barros Arana
SCHUMPETERIAN ‘GREAT GAP’ THESIS AND MEDIEVAL ISLAMIC ECONOMIC THOUGHT: INTERLINK BETWEEN GREEKS, MEDIEVAL ISLAMIC SCHOLARS AND EUROPEAN SCHOLASTICS
Authors: Rama Ali
Published: December 2017

Joseph Schumpeter (1883-1950) dalam bukunya History of Economic Analysis (1954)

memperkenalkan sebuah tesis ‘great gap’ dengan mengatakan bahwa analisis ekonomi hanya

mulai dari Yunani dan tidak berkembang lagi sampai kemunculan ilmuan Skolastik Eropa di

tangan St Thomas Aquinas. Namun kenyataannya, ‘great gap’ Schumpeter ini justru terjadi pada

masa kejayaan Islam, yaitu ketika sejumlah sarjana dan ilmuan Muslim memberikan kontribusi

signifikan dalam berbagai jenis penemuan dan keilmuan termasuk dalam bidang ekonomi. Isi

dari ilmu ekonomi kontemporer saat ini dapat dilacak kesamaannya dengan karya ilmuan Arab

abad pertengahan seperti Abu Yûsuf (731-798), Al Farabi (873-950), Ibnu Sina (980-1037), Al-

Ghazalî (1058-1111), Ibnu Taimiyah (1263-1328), dan Ibnu Khaldûm (1364-1442). Terdapat

keterhubungan antara karya intelektual Yunani, ilmuan Muslim abad pertengahan dan Ilmuan

skolastik. Ilmuan Arab sendiri ‘distimulasi’ oleh ilmuan Yunani yang selanjutnya dikembangkan

sesuai dengan kerangka Islam dan banyak dari karya mereka memiliki kemiripan dengan tulisan

Skolastik. Penelitian ini melakukan penolakan secara akademik atas tesis Shumpeter tentang

‘great gap’ dengan menunjukkan kontribusi ilmuan Muslim dalam pemikiran ekonomi.

Penelitian ini juga membahas beberapa isu tentang Islamisasi ilmu ekonomi kontemporer.
Identifikasi Metabolit Sekunder Dan Uji Aktivitas Antibakteri Isolat Jamur Endofit Daun Beluntas (Pluchea indica (L.) Less.)
Authors: Elviasari Jessie , Rusli Rolan , Ramadhan Adam M.
Published: December 2017

Eksploitasi berlebihan untuk memperoleh metabolit sekunder dari bahan alam dapat menyebabkan kepunahan bahan alam tersebut, sehingga solusi yang tepat yaitu melalui pengembangan mikroba endofit sebagai penghasil metabolit sekunder. Jamur endofit berpotensi menghasilkan metabolit sekunder seperti inangnya. Daun beluntas (Pluchea indica (L.) Less.) memiliki aktivitas sebagai antibakteri, maka diduga dapat pula isolat jamur endofit yang terdapat dalam jaringan daun beluntas menghasilkan metabolit sekunder yang sama dengan tanaman inangnya sehingga memungkinkan memiliki efek yang sama pula dengan tanaman inangnya. Tujuan penelitian ini adalah untuk mengidentifikasi golongan metabolit sekunder dan menguji aktivitas antibakteri metabolit sekunder yang dihasilkan isolat jamur endofit dari daun beluntas. Pengujian aktivitas sebagai antibakteri menggunakan metode difusi agar dengan menggunakan kertas cakram (paper disc). Bakteri uji yang digunakan adalah Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli dan Pseudomonas aeruginosa. Dari hasil isolasi jamur endofit diperoleh tiga isolat yaitu isolat jamur endofit putih, isolat jamur endofit hitam 1 dan isolat jamur endofit hitam 2 yang ketiganya memiliki kandungan metabolit sekunder yaitu fenol dan alkaloid. Dari ketiga isolat jamur endofit hanya satu jamur yang memiliki aktivitas menghambat pertumbuhan keempat bakteri uji tersebut yaitu ekstrak isolat jamur endofit hitam 2. Aktivitas antibakteri ekstrak isolat jamur endofit hitam 2 ditunjukkan dengan adanya daya hambat pada Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli dan Pseudomonas aeruginosa, dengan daya hambat berturut-turut sebesar 5,474 mm, 5,206 mm, 5,057 mm, dan 5,107 mm.
Analisis GC-MS Senyawa Aktif Antioksidan Fraksi Etil Asetat Daun Libo (Ficus variegata Blume.)
Authors: Novitasari Mega Rizky , Febrina Lizma , Agustina Risna , Rahmadani Agung , Rusli Rolan
Published: December 2017

Daun Libo (Ficus variegata Blume.) memiliki daun yang tidak dimakan oleh hama/serangga, hal ini diduga karena kandungan metabolit sekunder daun libo mengandung senyawa aktif yang potensial salah satunya adalah sebagai antioksidan. Penelitian ini dilakukan untuk mengetahui komponen senyawa antioksidan fraksi etil asetat daun libo dengan metode GC-MS. Interpretasi spektrum massa GC-MS dilakukan dengan menggunakan database WILLEY9THN 08.L. Hasil analisis spektrum GC-MS fraksi etil asetat aktif antioksidan mengandung 2,5-Cyclohexadiene-1,4-dione, 2,6-bis(1,1-dimethylethyl (0,65%), 1-Octadecene (1,29%), 2-Hexadecen-1-ol, 3,7,11,15-tetramethyl- (1,54%), 7,9-Di-tert-butyl-1-oxaspiro(4,5)deca-6,9-diene-2,8-dione (1,52%), 1-Nonadecene (3,39%), 1-Docosene (3,39%), Nonadecyltrifluoroacetate (2,12%), 1,2-Benzenedicarboxylic acid,(2-ethylhexyl) ester (45,53%), 1-Docosene (2,71%), Pyrene, hexadecahydro (4,56%), Urs-12-en-3-ol, acetate,(3.beta.) (1,97%), 12-Oleanen-3-yl acetate, (3.alpha.)- (5,19%), Urs-12-en-3-ol, acetate,(3.beta.) (1,53 %), Taraxasterol-acetate (0,30%), 1-(Dimethylamino)-5-{[4'-(5"-(4"'-iodophenyl ethynyl|)-1"-naphthylethynyl]-1(8,46%), dan 7,8,17,18-Tetrahydro-35-methoxy-1,3,21,23-tetramethyl-16H,31H-5,9,15,19-dime (10,04%).
Peningkatan Aktivitas Antimikroba Ekstrak Nanas (Ananas comosus (L.). Merr) dengan Pembentukan Nanopartikel
Authors: Rahmat Deni , Ratih L. Dian , Nurhidayati Liliek , Bathini Meilda Ayu
Published: December 2017

Bonggol nanas (Ananas comosus (L.). Merr) mengandung enzim bromelain dengan kadar tertinggi dibandingkan bagian nanas lainnya. Salah satu fungsi enzim bromelain adalah sebagai antimikroba. Ekstrak bonggol nanas dibuat dalam bentuk nanopartikel dengan menggunakan kitosan kemudian dikeringkan dengan metode freeze drying. Serbuk kering ekstrak ditentukan Konsentrasi Hambat Minimum (KHM) terhadap Staphylococcus aureus. Nanopartikel ekstrak kering dilakukan uji ukuran partikel, zeta potensial, dan morfologi partikel. Nanopartikel ekstrak kemudian diformulasikan ke dalam bentuk sediaan gel. Tiap formula dilakukan uji mutu fisik antara lain organoleptik, homogenitas, viskositas dan sifat alir dan uji mutu kimia (pH). Hasil penelitian menunjukkan nanopartikel ekstrak memiliki ukuran partikel 60,8 nm dan bentuk partikel kering sferis. Ekstrak bonggol nanas memiliki KHM pada konsentrasi 1,25%. Gel formula IV menunjukkan DDH tertinggi yaitu 62,5 mm dan memiliki viskositas dan pH yang stabil. Dengan demikian pembuatan nanopartikel pada ekstrak bonggol nanas dapat meningkatkan aktivitas antimikroba dalam sediaan gel untuk penggunaan secara topikal
Kadar Testosteron Darah Pasien Setelah Pemberian Jamu Aprodisiaka Di Rumah Riset Jamu“Hortus Medicus” Tawangmangu
Authors: Ardiyanto Danang , Mana Tofan Aries
Published: December 2017

Aprodisiaka dikenal sebagai zat untuk meningkatkan gairah seksual khususnya pada laki-laki. Pemberian jamu aprodisiaka untuk meningkatkan libido memerlukan bukti ilmiah yang memadai terutama dalam efikasinya. Salah satu indikator efikasi adalah dengan mengukur kadar testosteron darah.  Sebuah penelitian uji klinik dengan desain pre-post test telah dilakukan di Rumah Riset Jamu “Hortus Medicus” Balai Besar Litbang Tanaman Obat dan Obat Tradisional Tawangmangu untuk menilai kadar testoseron darah setelah pemberian jamu aprodiaka. Sebanyak 25 subjek secara sukarela mengikuti penelitian ini mendapatkan terapi formula jamu selama 2 bulan. Formula jamu merupakan infusa yang terdiri dari rimpang temulawak 15 gram, buah cabe jawa 3 gram, herba pegagan 9 gram, buah krangean 3 gram, biji adas 3 gram diminum 2 kali sehari. Kadar testosteron subyek diukur pada awal (hari ke-0), hari ke 28 dan hari ke 56. Hasil uji T antara kadar testosteron pada H-0 dibandingkan H-28, didapatkan nilai p=0,000, sedangkan hari ke-0 dibandingkan hari ke-56 didapapatkan nilai p=0,000. Hal tersebut menunjukkan perbedaan yang bermakna (p<0,05) antara sebelum dengan sesudah perlakuan. Dapat disimpulkan formula jamu untuk aprodisiaka meningkatkan kadar testosteron darah subjek.
Pemberian Ko-Kemoterapi Fraksi Etil Asetat Akar Pasak Bumi (Eurycoma longifolia Jack) terhadap Ekspresi Protein NF-K? pada Tikus Sprague Dawley yang Diinduksi DMBA
Authors: Putriani Kony , Nurani Laela Hayu , Widyarini Sitarina
Published: December 2017

Kanker payudara terjadi karena adanya paparan dari senyawa 7,12-dimethylbenz (a) antrasene (DMBA) yang bersifat mutagenik dan karsinogenik. Drug of choice untuk kanker payudara adalah Doxorubicin, namun menimbulkan efek samping dan toksik pada sel normal maka diperlukan penelitian ko-kemoterapi dalam hal ini digunakan fraksi etil asetat akar pasak bumi yang dapat bersifat sebagai antiinflamasi dan apoptosis.  Penelitian ini adalah untuk menelusuri mekanisme ko-kemoterapi akar pasak bumi dan Doxorubicin terhadap ekspresi protein NF-K? pada Tikus SD yang diinduksi DMBA. Akar pasak bumi (Eurycoma longifolia Jack) diekstraksi menggunakan pelarut etanol 70 % dan difraksinasi menggunakan etil asetat. Fraksi etil asetat akar pasak bumi diuji mekanisme molekulernya secara in vivo terhadap 5  Kelompok tikus  galur Sprague Dawley terdiri atas Kelompok 1 hanya diberi pakan dan minum, Kelompok 2 diberikan DMBA dosis 20 mg/kgBB, Kelompok 3 diberikan DMBA 20 mg/kgBB + Doxorubicin 1,17 mg/kgBB, Kelompok 4 diberikan DMBA 20 mg/kgBB + fraksi etil asetat akar pasak bumi 100 mg/kgBB, Kelompok 5 diberikan DMBA 20 mg/kgBB + Doxorubicin 1,17 mg/kgBB + fraksi etil asetat akar pasak bumi 100 mg/kgBB kemudian dilakukan pembedahan dan uji imunohistokimia  analisis data Kolmogorof Smirnof, uji Levene, uji ANOVA atau Kruskal Wallis. Hasil nilai rata-rata % ekspresi protein NF-K? adalah (6,64± 11,28)%, (39,53± 16,49)%, (18,10± 15,08%, (16,66± 12,51)% dan (15,39± 8,76)%. Kesimpulan dari penelitian ini adalah kombinasi fraksi etil asetat ekstrak etanol akar pasak bumi dan Doxorubicin dapat menurunkan ekspresi protein NF-K? dan terhadap tikus galur Sprague Dawley yang diinduksi DMBA.
Karakterisasi Ekstrak Daun Cantigi (Vaccinium varingiaefolium Miq.)
Authors: Yulyana Ana , Winarno Hendig , Kosasih Kosasih
Published: December 2017

Cantigi (Vaccinium varingiaefolium Miq.) banyak tumbuh di sekitar kawah gunung berapi namun belum banyak informasi yang terkuak. Tujuan penelitian: Melakukan karakterisasi ekstrak daun Cantigi yang diekstraksi secara maserasi menggunakan pelarut n-heksan, etilasetat, dan etanol 95%; penapisan fitokimia ekstrak; uji aktivitas sitotoksik ekstrak; fraksinasi ekstrak dengan kromatografi kolom; uji sitotoksik fraksi; pembuatan profil GC/MS fraksi teraktif. Hasil penelitian: Hasil penapisan fitokimia menunjukkan positif untuk flavonoid, steroid, tannin, dan triterpenoid. Aktivitas sitotoksik pada sel leukemia L1210 (IC50) 12,67; 8,29; dan 10,42 µg/mL. Fraksinasi ekstrak teraktif etilasetat (Kromatografi kolom: Fase diam silika gel 60, fase gerak kloroform:metanol 10:1, 8:1, dan 4:1) diperoleh 4 fraksi. Aktivitas sitotoksik (IC50) Fraksi 1-4 adalah 3,62;  1,69; 2,98; dan 2,96 µg/mL. Karakterisasi fraksi F2 dengan GC/MS menunjukkan 15 senyawa. Simpulan: Aktivitas sitotoksik fraksi ekstrak etilasetat (F2) lebih tinggi dibandingkan non-fraksi ekstrak etilasetat dan ini belum pernah dilaporkan sebelumnya.
WORLD ENGLISHES FROM A HOLISTIC VIEW AND CONSIDERATIONS ON ENGLISH EDUCATION IN VIETNAM
Authors: Hao Tran Thi , Phuong Ngo Dinh
Published: December 2017

The development of English as the mutual language among ASEAN since 2008 and the formation of ASEAN Economic Community since 2015 have set milestones in the social and educational development of each country in this organisation. In English education in Vietnam, understanding the diversity of Englishes in the organisation has become an important task. This article aims to present a holistic view of World Englishes (WE) in research generally and in relation to English education in Vietnam particularly by illustrating the Vietnamese English teachers’ perceptions of WE in the Vietnamese teaching context. The data were collected via an online questionnaire using a snowball sampling method from seventy-six respondents who are English lecturers from twenty-six universities or colleges in Vietnam. The data were also collected from focus group interviews with fve participants who were doing Master Degree in Applied Linguistics at an Australian university. The article delineates the fndings of the Vietnamese English teachers’ perceptions towards WE and their experiences in introducing WE in their teaching context. Discussion of English education in Vietnam, including issues in English teaching, English teachers’ development and considerations of the policy context, is also be presented.
SPEECH ACT TYPES IN CONVERSATIONS IN THE “NEW INTERCHANGE” SERIES
Authors: Ngoan Nguyen Quang , Dung Nguyen Thi Ngoc
Published: December 2017

This is a study of speech acts in the conversations of New Interchange 1, 2, and 3. The aim of the study is to examine speech act types in the conversations investigated. Both quantitative approach and qualitative approach are employed with the assistance of descriptive, contrastive, analytic, and synthetic methods to help work out the best possible fndings. The data consist of a total of 784 turns comprising 8126 words in 97 conversations of New Interchange 1, 2, and 3. The study shows interesting results concerning speech act types. To be more specifc, although there is a strong tendency for combination of different speech act types, single speech act groups are preferred with the predominance of representatives.
A MULTIMODAL ANALYSIS OF MATHEMATICAL DISCOURSE IN ENGLISH FOR YOUNG LEARNERS
Authors: Nhat Ton Nu My
Published: December 2017

Of multiple discourses where the Vietnamese young learners are increasingly engaged to develop their English profciency, English mathematical discourse (MD) has proved to be more and more popular. This paper explores the materials in this realm from multisemiotic perspective. In particular, it deals with two questions: (1) to what extent each of the three semiotic resources - language, visual images and mathematical symbolism - is represented in the materials of learning mathematics in English (ME) developed for young learners (YL) and (2) how many words the YLs need to know to comprehend the language component of these materials. Data for illustrations and discussions are withdrawn from the printed resources currently accessible in the Vietnamese context. The results offer insights into the functions of other resources in constructing meanings apart from the well-established role of language as well as the vocabulary load of these materials. The paper concludes with a discussion of pedagogical signifcance of this study for material designers, teachers and learners and implications for further research.
MAJOR CONTEMPORARY APPROACHES TO THE ANALYSIS OF THE VIETNAMESE SIMPLE CLAUSE
Authors: Trinh Nguyen Thi Tu , Hoa Phan Van , Phuc Tran Huu
Published: December 2017

Clause as a grammatical category has been at the centre of attention throughout most of the history of linguistics in Vietnam and has caused a lot of troubles for analysis and interpretation. Great efforts have been made to shed light on this matter. There is, however, no consensus among Vietnamese linguists on clause analysis and interpretation because each of them seems to work on clause analysis in a variety of approaches using different frameworks. In this paper, we aim at investigating some major contemporary approaches to the analysis of the Vietnamese simple clause with our critical appraisals of each approach toprovide readers with an overview of Vietnamese clause studies. The study reveals that at present structuralapproaches inﬂuenced by European and American structuralists such as Saussure and Bloomfeld, andfunctional approaches inﬂuenced by Dik’s functional grammar and Halliday’s systemic functional grammarseem to be the dominant grammatical models for the analysis of the Vietnamese simple clause.
THE EFFECTIVENESS OF COLLABORATIVE BRAINSTORMING TRAINING PROCEDURES AT PRE-WRITING STAGE IN INTERMEDIATE ENGLISH CLASSES
Authors: Tuyet Tran Thi Anh
Published: December 2017

This article reports a qualitative action study that emerged from the author’s reﬂective teaching practice in an intermediate English class. The research investigated the effectiveness of collaborative brainstorming training procedures on students’ ideas expressed in their written papers and on students’ learning of writing skills through in-depth interviews, classroom observations, students’ written papers and students’ journals. The study indicates that collaborative brainstorming training with additional brainstorming rules can signifcantly improve quantity and quality of ideas in paragraph writing, but not remarkably in letter writing. Besides, training has had positive effects on students’ learning of writing skills. The fndings of the study, therefore, make important contributions to the implementation of collaborative brainstorming in the English language teaching practice.
Estimation of genetic diversity for quantitative traits of commercial wheat (Triticum aestivum)
Authors: Rasheed Adnan , Solangi Abdul Malik
Published: December 2017

This research was conducted to assess the performance of wheat genotypes and to detect genotypes with adult plant resistance by evaluating them in a trap nursery. 36 commercial wheat cultivar were used in experiment. Morocco was sown on four sides of trial. Material was sown in augmented design. The data was recorded on different quantitative like Plant height (cm), no. of tillers/plant, spike length (cm), no of spikelets/plant, peduncle length (cm), stem diameter (mm) and flag leaf area. Selection of genotypes could be done from two main clusters to make cross for improvement of traits. No of tillers/plant, peduncle length, spike/length, spikelets/plant and plant height showed large genetic variability in Biplot and these variables could be used as selection criteria. Pak-81, Sindh-81, Mexipak-65, Sarsabaz, Chakwal-86 and Kiran-95 so these cultivars could be potentially used in future breeding programme for improvement of several quantitative traits according to results of Biplot analysis. Following genotypes were found moderate resistant against yellow rust viz. Anmol-9, Bahawalpur-200 and Bakhtawar-92 and could be used further in future breeding programme to stand against yellow ruts pressure. Maxipak-65 and WL-711 need to improve by incorporating yellow rust resistant genes.
Penerapan Workbook Matematika Berbasis Kontekstual
Authors: Wulandari Tri Candra , Rahayu Sri
Published: December 2017

Mathematics in primary schools still rely on textbooks and workbooks students were also issued by the government. In general, it seems simpler both from the teachers and students, because students only carry one book that contains a variety of subjects. Weak concept is very pronounced in mathematics. In integrated math into the thematic lessons, however, mathematics remains one of the subjects tested on a final school examinations. Teachers are preparing for the final exam had to work hard to repeat concepts ranging from grade 1 to grade 5. Therefore, it is necessary for teachers of proven strategies so that the material presented can be accepted students well. This research purposed to describe the application of contextual learning using math workbook. This study uses qualitative research with 30 research subjects third grade elementary school students in SDN Gandang I Malang. Data collection technique used documentation techniques and tests. Data analysis technique used qualitative descriptive analysis. After implementing the learning using the workbook, the average repeat is 86.96, the lowest score and the highest score each are 70 and 100. Based on the results obtained, contextual workbook that directly relate to the theme 7 that the energy source can be applied to the study of mathematics the third class at SDN Gadang I Malang.
IMPLEMENTASI KEGIATAN OUTBOUND DALAM UPAYA PEMBENTUKAN PERILAKU SOSIAL DAN EMOSIONAL ANAK USIA DINI
Authors: Susari Hermawati Dwi
Published: December 2017

As social beings, egocentrism which is a character of preschoolers needs to be encouraged and guided in order not to hinder their future socialization in their community. In that perspective, this research aims to investigate how to use outbond activity as a means to build social-emotional behaviors of preschoolers. The results show that the social and emotional behaviors of the preschoolers at the kindergarten Sekolah Alam Bandung developed fairly well. Their emotion showed their ability to identify and understand the emotion they were experiencing but not able to control it. The plan and the application were already on the right track. However, there should be improvement. Problems encountered involved teacher’s restriction of knowledge, and the skill to serve as a preschool educator as well as the outbond facilitator. It was shown that the outbond activity affected less signifacntly their social and emotional behaviors. Accordingly, it is recommended the significance of enhancing teachers’ knowledge and skills in designing, applying and evaluating the outbond activity in order to better build preschoolers’ social and emotional behaviors.
PENDEKATAN ALTERNATIF DALAM PELAKSANAAN SUPERVISI PENGAJARAN
Authors: Gunawan Imam
Published: December 2017

Teaching supervision may aim to create a better learning atmosphere, guide teachers’ teaching experience, and help the teacher assess their students. A supervisor motivation to teachers can improve their commitment. There are approaches to supervision and dimensions to classify teachers to help supervisors select the approach to adopt. Among the approaches are the clinic, directive, non-directive, collaborative, informal, collegial, and individual related to teacher dimensions such as extent of attention, responsibility, maturity, and cognitive complexity of the teachers which ease to choose recommended approaches to apply in the supervising.
KURIKULUM BERBASIS KOMPETENSI (Konsep Dasar dan Implementasi)
Authors: Rifai Moh
Published: December 2017

In effort of the nation surival, a society need a set of educations which are then termed as competence so as to be proffesional, competitive and merit. The basic competence has become the substance of success in live and living. The breakdown of the nation’s economy, education, culture and also monetary affairs is not due to the lack of the government power, rather a lack of the basic competence possessed by the political actors, which needs to be questioned. Unfortunately, the prosperity of Indonesian nature can not bring Indonesia to become the master in our own nation, but it does them poverty due to live under pressure of other nation. It has been caused by the lack of the basic competence of our nation in managing, preserving, utilizing the nation’s prosperity.
KAJIAN NILAI, FUNGSI, DAN MAKNA YANG TERKANDUNG DALAM SENI DONGKREK
Authors: Hartini Hartini
Published: December 2017

Dongkrek attraction is a stage which is composed of music, dance and dramatic story arranged in a single set of show. The structure of the stage is seen in the unique type of music instrument. Masks have become the reflection of the characterization of the characters in stage. The music intsruments of Dongkrek attraction are: kenthongan, kenong, bedug, beri, korek and gong pamungkas. The masks are typified as topeng buta/gendruwo; topeng roro perot, topeng roro ayu and topeng eyang palang. Cultural values reflected in Dongkrek attraction consist of those of education, moral, leadership, heroism and aesthetics. Dongkrek attraction can also serve functions of fulfiling psychological needs, expressing self-esttem, releasing tension and ammusement. The masks in Dongkrek represent some characters; topeng buta/gendruwo for evil, eyang palang for wisdom.
MEMBANGUN PENDIDIKAN KARAKTER GENERASI MUDA MELALUI BUDAYA KEARIFAN LOKAL DI ERA GLOBAL
Authors: Budiwibowo Satrijo
Published: December 2017

The parameter of the nation’s achievement is that of youth in the future, because maintaining the achievement is usually more difficult than fighting for it. Youth are young generation who are ablidged to maintain leadership and struggle to stay fit around the stricker competition in all aspects due to the higher velocity of service capital throughout the world, which influence the national integrity of a nation. This can only be resolved by producing human resource with high competitive advantage. Globalization has become the term to call a world condition which takes place without boreder. The globalization progress has evidently stood aside local wisdoms of a nation. This article serves an aoutlook on the efforts of universal character building which is rooted from the local wisdom.
PENGARUH KONSENTRASI DAN KEMAMPUAN BERPIKIR KRITIS TERHADAP PRESTASI BELAJAR IPS SISWA KELAS V SDN MANISREJO I KABUPATEN MAGETAN
Authors: Malawi Ibadullah , Tristiar AA
Published: December 2017

The goal of research to determin the relationship among concentration and critical thinking with learning achievement of grade V for the student SDN Manisrejo 1 Magetan. This research applies descriptive correlasional and expost facto method with quantitative approach. The population of this research consist of 33 student. The result of the analysis show that: (1) there is significant relationship between the concentration with learning achievement by t (2,564), (p) 0,016; (2) there is significant relationship between the critical thinking with learning achievement by t (2,063), (p) 0,048; and (3) there is significant relationship between the concentration and critical thinking with learning achievement by F (10,802), (p) = 0,000.

Key words: Concentration, Critical Thinking, Learning Achievement
Pendekatan Pembelajaran Struktural Think-Pair-Share dalam Peningkatan Kemampuan Mendeskripsikan dan Mempraktikkan Shalat Fardlu Siswa Sekolah Dasar
Authors: Sahudi Sahudi
Published: December 2017

Pendidikan Agama Islam di Sekolah Dasar bertujuan untuk menumbuhkan dan meningkatkan keimanan, melalui pemberian dan pemupukan pengetahuan, penghayatan, pengamalan serta pengalaman peserta didik tentang agama Islam. Penelitian ini membahas kemampuan mendeskripsikan dan mempraktikkan Shalat Fardu dengan menerapkan pembelajaran Think-Pair-Share. Pendekatan struktural Think-Pair-Share merupakan cara yang efektif untuk mengubah pola diskursus di dalam kelas. Think-Pair-Shere memiliki prosedur yang ditetapkan secara eksplisit untuk memberi siswa waktu lebih banyak untuk berfikir, menjawab, dan saling membantu satu sama lain. Hasil analisa data per siklus dapat diketahui dari nilai rata-rata pada siklus I  65,00, nilai rata-rata pada siklus II 76,88 dan siklus III rata rata 86,88. Dengan demikian dapat disimpulkan bahwa implementasi dari siklus ke siklus berikutnya mengalami peningkatan baik secara individual maupun klasikal. Dari hasil nilai tersebut dapat disimpulkan bahwa ada peningkatan kemampuan mendeskripsikan dan mempraktikkan Shalat Fardu dengan pendekatan Struktural Think-Pair-Share pada siswa kelas III SDN 2 Munggu Kecamatan Bungkal Ponorogo tahun pelajaran 2015/2016.
Pengaruh Model Pembelajaran Perubahan Konseptual (MPPK) Terhadap Hasil Belajar IPS dan Sikap Multikultural Siswa Sekolah Dasar Berlatar Belakang Monokultur
Authors: Rapih Subroto , Sutaryanto Sutaryanto
Published: December 2017

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh metode pembelajaran perubahan konseptual pada hasil belajar IPS dan sikap multikultural siswa Sekolah Dasar yang berada di wilayah Desa Gondosuli, Kecamatan Tawangmangu, Kabupaten Karanganyar. Penelitian ini menggunakan rancangan penelitian eksperimen dalam bentuk Post-Test Only Control Group Design. Penelitian ini melibatkan tiga variabel yang terdiri dari satu variabel bebas dan dua variabel terikat. Variabel bebas adalah model pembelajaran perubahan konseptuan sedangkan variabel terikat yaitu prestasi belajar IPS dan sikap multikultural siswa. Data dalam penelitian ini dianalisis menggunakan analisis inferensial dengan menggunakan analisis statistik multivariat (MONOVA). Hasil penelitian menunjukkan bahwa: 1) terdapat perbedaan hasil belajar IPS dan kesadaran multikultural pada siswa yang mengikuti pembelajaran perubahan konseptual dengan siswa yang mengikuti pembelajaran konvensional dengan hasil perhitungan F: 40,222;p<0.05. 2) terdapat perbedaan hasil belajar IPS pada siswa yang mengikuti pembelajaran perubahan konseptual dengan siswa yang mengikuti pembelajaran konvensional dengan hasil perhitungan F: 70.520;p<0.05. 3) terdapat perbedaan kesadaran multikultural pada siswa yang mengikuti pembelajaran perubahan konseptual dengan siswa yang mengikuti pembelajaran konvensional dengan hasil perhitungan F: 12.089;p<0.05. Berdasarkan hasil uji hipotesis dapat disimpulkan bahwa penerapan metode pembalajaran perubahan konseptual berpengaruh pada hasil belajar mata pelajaran IPS dan kesadaran multikultural siswa kelas IV Sekolah Dasar di wilayah Desa Gondosuli.
Can Objectivists Account for Subjective Reasons?
Authors: Wodak Daniel
Published: December 2017

Abstract here.
Immigration Policy and Identification Across Borders
Authors: Lindauer Matthew
Published: December 2017

According to the traditional state sovereignty view in the ethics of immigration literature, societies have a great deal of latitude in determining and implementing their immigration policies. This view is typically defended by appealing to the rights of members of societies, for instance to political self-determination. Opponents of the view have often criticized its partiality to members, arguing that nonmembers can also make stringent demands on societies to be admitted and given the same treatment in matters of immigration policy as other nonmembers. In this paper, I take a different approach to responding to the state sovereignty view. I argue that even if we grant the premise that the rights of members generally trump the rights of nonmembers in matters of immigration policy, societies are greatly constrained in setting their immigration policies by considerations of domestic justice. The considerations that I focus on involve relationships between members and nonmembers that hold due to a shared quality or set of qualities on the basis of which members identify with nonmembers. The argument appeals to premises and principles that defenders of the state sovereignty view are committed to but concludes that this view cannot serve as a satisfactory framework for the normative assessment of immigration policies.
Can We Intend the Past?
Authors: Na'aman Oded
Published: December 2017

Abstract here.
NOTE-TAKING OF ENGLISH LESSONS AT TERTIARY LEVEL: A CONTEXT OF BANGLADESH
Authors: Islam Farzana Sharmin Pamela
Published: December 2017

Note-taking is a common and an important classroom activity. Notes that students create in class while listening to the lectures given by lecturers, or while they review course material, become an important means of learning. It is a general perception of many learners and many of their instructors as well that note-taking is a common manifestation and intuitive skill to have, yet a few considers differently and encourage best practices for better performance. Unfortunately, many students are unaware of its benefits and so fail to appreciate that effective note-taking contributes to a great extent to their learning, and so the importance of cultivating their note-taking skills in course of their education period. This paper based on qualitative analysis provides an overview of how Bangladeshi students follow different strategies to take down notes in lecture sessions at tertiary level. The primary data for this paper has been collected from 35 studentsâ€™ paragraph writing on a topic â€˜How to take notes in a lectureâ€™ in which the students were asked to reflect on their own note-taking strategies, how they get benefit from their notes, and their subsequent retrieval of information from the notes later on. The participants were from a â€˜Basic Englishâ€™ course as well as from English core courses at a highly rated private university in a metropolitan city in Bangladesh.Â  This case study evolves around four aspects of note taking: firstly, the principal functions of note-taking; secondly, the main strategies students used for note-taking; thirdly, the benefits that the students derive through various approaches to note-taking; and lastly, the initiatives to improve the art of note taking as a successful tool in learning target subject matter. While some of the findings are in line with earlier studies, a few of them have their own uniqueness.