bluuebunny/crossref_metadata_2025 huggingface dataset:
Sleep Patterns and Academic Performance among Medicine and Pharm D students in Almaarefa University 2018-2019
Authors: Alzunidi Mashel A. , Alowayyid Jawaher A , Benhadi Rabab A , Farouk Habiba H. , Alshammari Malak H. , Sultan Asmaa S. , Almojil Rana A. , Alshathri Alanoud A. , Alsalman Noor N. , Alshaya Shahad S. , Alfadeel Mona M.
Published: May 2022

Background: Sleep is an important necessity in the human life. The majority of grown-ups require seven and a half to nine hours of sleep every night to work at their full capacity. Sleep deprivation is a common finding in students’ academic life. Objectives: To assess the relation between sleep pattern and academic performance among Almaarefa University medical and pharmacy students in Riyadh. Methods: An observational, descriptive, cross-sectional study. Among 162 Medical and Pharm D students. In Almaarefa University, Riyadh. It was done by a questionnaire. Data was analyzed using (SPSS). Results: Among the included students, Findings regarding the relation between gender and depth of sleep was statistically insignificant, showed that deep sleep is 43% among males and 28% among females was considered statistically significant. Regarding shared or separated rooms, and factors. 66% used separated room. For females the shared rooms amounted to 38% while it was 19% in males. Regarding major, approximately 66% of students reported using separate rooms. For medicine students the separate rooms amounted to 71% while it was 57% among pharmacy students was also statically significant Conclusion: Sleep pattern and GPA had no relation. However, male students had deeper sleep than females. The percentage of female students in a shared room was higher than males. Finally, medical students had a higher percentage in sharing a room than pharmacy students. Most of the respondents are majoring in medicine, as well as females were triple the number of males, this may have affected the results. Key words: sleep, performance, University, student, Saudi
Prevalence of Anxiety and Depression among postgraduate trainees in Qassim, Saudi Arabia
Authors: Alrasheedi Jamal , Rabbani Unaib
Published: May 2022

Background: Trainee doctors in postgraduate programs go through many challenges and stressor events in their life which may affect their mental health. Objective: This study aimed to measure the prevalence and risk factor of depression, anxiety and stress among trainees of Saudi Board programs in Qassim region. Materials & Methods: A cross-sectional study was conducted among 119 postgraduate trainees enrolled in Saudi Board Program in Qassim region. Depression Anxiety and Stress Scale (DASS-21) was used to measure the outcome variables. Logistic regression was used to assess the risk factors of depression, anxiety and stress. Results: A quarter (25%) of the respondents were female, and half (51%) were married. The prevalence of depression, anxiety and stress were 49.6%, 57% and 39.5% respectively. We found that failing the promotion exam adjusted odds ratio (AOR) 4.43(95% CI: 1.45-13.50), being in Internal medicine AOR 3.94 (95% CI: 1.22 - 12.66) and other specialties AOR 3.56 (95% CI: 1.22-10.39) were significant risk factors of depression. Risk factors for anxiety included; failing promotion exam AOR 4.46 (1.18-16.86) and being in internal medicine AOR 8.95(95% CI: 2.39-30.84) and other specialties AOR 5.78 (95% CI: 1.88-18.72). On the other hand, being unmarried was protective of anxiety AOR 0.23(95%CI: 0.08-0.60). The only significant factor associated with stress was not passing part one exam AOR 5.06 (95% CI: 1.70 - 15.1). Conclusions: We found a high prevalence of mental disorders among postgraduate trainees in Qassim region of Saudi Arabia. This calls for implementing screening and support programs for trainees to improve their mental health and thus their learning and quality of care being provided by them. Key words: Anxiety, Depression, Stress, Trainees, Postgraduate, Saudi Arabia
Knowledge of Amblyopia among Primary Health Care Physicians and Family Medicine Residents: A Cross-Sectional Study in the Qassim Region of Saudi Arabia
Authors: Aldekhail Noha Dekhail , Sulaiman Amel Abdalrahim
Published: May 2022

Background: Amblyopia is a serious visual impairment resulting from abnormal visual stimulation during early childhood. Early detection of childhood visual abnormalities will reduce adult visual impairment. This study aimed to assess the knowledge of Amblyopia among primary Health Care (PHC) physicians and Family Medicine Residents (FMA) in Qassim Region. Methods: A cross-sectional study enrolled 197 PHC physicians and residents from FMA. Data were collected through an online questionnaire with variables on physicians’ knowledge about amblyopia based on the Canadian Pediatric Society Recommendations for Vision Screening at Infant and Well Child Visits. The data was analyzed using SPSS version 21. Results: The respondent’s average age was 35 (SD ± 8.00). Males were 103(52.3%); the majority were Saudi 120 (60.9%). Most of them, 189 (96%) knew the definition of amblyopia. But the majority of physicians, 138 (70%) had not seen or diagnosed any case of amblyopia before . The overall knowledge of the family medicine residents and PHC physicians regarding amblyopia’s prevalence rate, causes, examination, and treatment was good at 178 (90.4%). However, their knowledge of referral criteria for amblyopia cases still needed more updating. No statistical relationship was identified between the participant’s demographic characteristics and their level of knowledge. Conclusions: This study highlighted a good knowledge level regarding amblyopia among primary health care physicians and family medicine residents. However, strategies to improve vision screening are necessary. Early intervention is crucial to prevent treatable causes of vision loss in children. Keywords: Amblyopia; vision screening; Primary health Care; Qassim; Saudi Arabia
Complementary and alternative medicine practice and perceptions of Saudi subjects in Western region of Saudi Arabia
Authors: El-Gamal Fathi , Bajubair Abdulaziz , Hejji Aljawhara , Jarwan Aseel , Salah Jamil Numan
Published: May 2022

Background: Complementary and alternative medicine (CAM) offers a different approach to conventional medicine. CAM is very popular in many countries. Objectives: To study the magnitude of use, and determinants and awareness of CAM therapy use among the population in Western region of Saudi Arabia. Method: This was a cross sectional study; a non-probability convenient sampling method was used to select 1073 subjects through online Google survey. Data were collected using interview questionnaire, which provided information on the sociodemographic characteristics of the subjects, as well as questions on the practices and awareness of CAM therapies. The GAD-7 test to assess anxiety state was also used. Results: Almost half of the study population used CAM (51.6%), particularly those who live in the villages of Makkah city. CAM therapies were used by almost half of all patients with chronic diseases particularly those with gastrointestinal disorders and anxiety. Most common CAM method were Honey, Herbs, Ruqayyah and black seeds; while Acupuncture was the least method used. CAM methods were mainly used if needed, and main source of information about its use, was from the family. Almost half of the users were satisfied with the results of using it; however, their attitude about CAM in general was neutral. Conclusion: Use of CAM is a common health practice among the Saudi population. The majority of the participants had equivocal awareness about its effects. More health education programs by specialized health care authorities on the use and benefits of CAM are needed. Doctor-patient communication regarding CAM use is important. Increasing awareness of Saudi population about instructions and restrictions when using CAM is greatly needed. Keywords: CAM, Saudi Arabia, anxiety, Jeddah city, Gastro intestinal disorders.
The prevalence of unplanned pregnancy among women attending antenatal primary care clinics in Qatar
Authors: Alam Muhammad Tanveer , Veettil Shajitha Thekke , Khudhadad Hanan , Islam Nazmul
Published: May 2022

Background: Currently, 40% of pregnancies worldwide are unplanned and leading to approximately 42 million induced abortions per year, and 34 million unintended births. Objectives: This study aims to ascertain the prevalence of unintended pregnancies among antenatal women attending antenatal clinics in Primary Care in Qatar and to establish any demographic differences among antenatal women around the choice of pregnancy. Methodology: A cross-sectional descriptive study with convenience sampling was used to recruit the participants. A validated questionnaire (the London Measure of Unplanned Pregnancy (LMUP)) was used to look at the prevalence and hence the size of the problem. Results: Among 107 participants, scores on the LMUP ranged from 0-12 with a median of 10. Most pregnancies 79.4%, (n=85) were categorized as planned, 17.8% (n=19) as ambivalent, and 2.8% (n=3) as unplanned. 71% of women (n=76) described their current pregnancy as ‘wanted’, and 20.6% (n=22) as ‘mixed feelings’ and 8.4% of women (n=9)defined their pregnancy as ‘unwanted’. Women who are married for more than 5-years (:-1.50, 95%CI -2.47 to -0.52, p=0.003) tended to have significantly lower LMUP scores, and hence a higher risk of having a more unplanned pregnancy. However, women who are non-Qatari’s (:6.30, 95%CI 3.30 to 9.30, p<0.001) and have more than 5-years since last delivery (:2.32, 95%CI 0.95 to 3.68, p=0.001) have significantly higher LMUP scores and hence a lower risk of having a more unplanned pregnancy. Conclusion: Unplanned pregnancies in this population are rare among women attending antenatal clinics. Less planned pregnancies tended to be more prevalent among Qatari women compared to expatriates. Unplanned pregnancy prevention services need to be included within pregnancy care services in primary care settings to offer preferred contraception on time to effectively maintain the low rate of unplanned pregnancies in the country. Key words: Prevalence, unplanned pregnancy, antenatal clinics, primary care, Qatar
Clinical and Para-clinical Findings of COVID19 in Hemodialysis Patients Compared to Control Group: A Case-Control Study
Authors: Shahreki Elham , Ansari-Moghaddam AliReza , Alavi Naini Roya , Keikha Maryam , Bazi Ramin , Shahraki Ahmad Reza
Published: May 2022

Background: Following the global outbreak of severe acute respiratory syndrome coronavirus 2 in different communities, hemodialysis patients have not been spared by this viral infection. Objectives: This study evaluated the clinical symptoms laboratory and imaging findings in patients undergoing hemodialysis and compared these characteristics with the control group. Methods: The study was performed on 72 patients with positive COVID-19 polymerase chain reaction test, of whom 36 cases had end-stage renal disease undergoing hemodialysis and the remaining had no history of kidney diseases. After matching the two groups in terms of age, sex, and other underlying diseases, the clinical, laboratory, and chest computed tomography (CT) scan findings were compared between the case and control groups. Results: The mean age of dialysis patients was 42.52 ± 12.10 years and 48.58 ± 17.35 years in the control group. The study results revealed that hemodialysis patients had less fever, cough, and shortness of breath than the control group (P-value < 0.05). Hemoglobin, lymphocyte, and platelet counts were significantly lower in hemodialysis patients in comparison to the control group (P-value < 0.05). C-reactive protein was significantly higher in patients undergoing hemodialysis (P-value < 0.05), and ground-glass opacification was observed more in patients undergoing hemodialysis compared to controls, but this difference was not statically significant (P > 0.05). Conclusions: Hemodialysis patients had fewer initial clinical symptoms but more abnormalities in laboratory findings and ground-glass opacities on chest CT scans and a higher mortality rate.
To Pardon what Conscience Dreads
Authors: Lisowski R. James ,   Philosophy Documentation Center
Published: May 2022

This article will examine the religious phenomenology of Max Scheler as it is found in his essay on repentance. In outlining Scheler’s understanding of repentance, I shall note his attempt at defining the phenomenon, as well as the presuppositions to and outcomes of this religious act. With this foundation laid, I shall then offer two critiques. First, Scheler’s rendering of repentance limps in not accounting for the cyclical and repeatable nature of repentance, to which human experience and Scheler’s own broader philosophy attest. Second, Scheler’s essay does not consider the role of other persons both in leading one to repentance and in completing the process. As with the first critique, both human experience and Scheler’s own personalist philosophy testify to the necessary role of other persons. These lacunae detract from the otherwise rich phenomenological account.
Can unexpected support promote environmental policy acceptability? An experimental investigation of norm source and strength
Authors: Ejelöv Emma , Hansla André , Nilsson Andreas
Published: May 2022

Two experiments tested how environmental policy acceptability of US conservatives and liberals was influenced by manipulating the level (minority vs. majority) and source (in-group vs. outgroup) of normative support for policy. Results from 928 MechanicalTurk users (Study 1: N = 268, Study 2: N = 660) indicated that when evaluating an in-group policy (that participants expect their own political group to support), communicating outgroup support increases acceptability compared with communicating in-group support. The outgroup norm has a positive indirect effect via the inference that the in-group is even more supportive of the policy than the outgroup is. In contrast, when evaluating an outgroup policy, communicating in-group support indirectly yields higher acceptability than communicating outgroup support, via the inference that the outgroup is more supportive than the in-group is. This effect mainly occurred for individuals with strong ideological identification and was independent of level of support (minority vs. majority). Results indicate that bipartisan support for environmental policies can be achieved by strategic communication of normative information about political groups.
Os modelos de homem e as teorias da administração: de Taylor ao Guerreiro Ramos
Authors: Marques Mariana Pereira , Nunes Carine de Oliveira
Published: May 2022

O objetivo deste estudo é identificar os modelos de homem existentes nas Teorias da Administração e os apresentados por Guerreiro Ramos, buscando estabelecer uma conexão entre os dois. Trata-se de uma pesquisa descritiva, com abordagem qualitativa, a qual foi realizada via levantamento bibliográfico das principais Teorias da Administração e dos modelos de homem desencadeados por cada uma delas, além de pesquisa bibliográfica sobre os modelos de homem de Guerreiro Ramos. Observou-se a existência de três modelos de homem, nos textos de Guerreiro Ramos, primeiro é o homem operacional, que pode ser comparado ao homo economicus da Teoria Clássica da Administração; Homem Reativo, que surge em consonância com a Teoria das Relações Humanas e pode ser comparado ao Homo socialis e; Homem Parentético, modelo mais sofisticado dos três, em que o indivíduo suspende a crença no mundo comum e rompe as suas raízes, atingindo um nível de reflexão conceitual, portanto, de liberdade.
Análise do clima organizacional do setor financeiro de uma empresa de telecomunicações da cidade de Pereiro/CE
Authors: Cordeiro Mycaele Vaz de Lima , Rego Filho Francisco Souza , Costa Yascara Pryscilla Dantas , Mesquita Álisson Caio Abrantes de , Holanda João Clécio de Sousa
Published: May 2022

O clima organizacional é entendido como um conjunto de valores, atitudes e padrões que tem capacidade de influenciar o desempenho dos colaboradores, se tornando uma ferramenta necessária para a boa condução das organizações modernas. Assim, este artigo foi elaborado a partir de uma pesquisa que analisou o clima organizacional de um setor financeiro de uma empresa de telecomunicações da cidade de Pereiro/CE. A amostra foi constituída por 40 sujeitos e o instrumento utilizados foi um questionário com questões fechadas e escalares. Os dados coletados foram analisados através da ferramenta Google Forms. Como resultados, constatou-se que 80% dos sujeitos estão motivados pela empresa, pelo gestor e automotivados; em relação a remuneração, média de 65% dos respondentes se sentem satisfeitos, 45% concordam com o salário que recebem, 30% estão indecisos e 25% não concordam; sobre o estresse, foi identificado que 22,5% disseram sentir-se estressados 5 vezes ou mais durante a semana; se tratando do ambiente de trabalho, 85% demostram estarem satisfeitos. Em conclusão, se infere que a organização possui um ótimo clima organizacional no seu setor financeiro, representando um diferencial competitivo para ela. Por fim, admite-se a limitação do estudo por ter sido realizado somente em um setor e se sugere que estudos de mesmo teor sejam realizados em outras áreas da organização.
A qualidade da gestão de recursos humanos na percepção dos funcionários: um estudo de caso na OAB/PI
Authors: Barbosa Aldevânia Cardoso , Lima Francisco Valdivino Rocha
Published: May 2022

As pessoas são essenciais no contexto das organizações. São elas (as pessoas) que formulam, planejam e implementam estratégias e processos operacionais, com foco no alcance dos objetivos organizacionais. Neste contexto, esta pesquisa tem como objetivo analisar a percepção dos funcionários acerca da qualidade dos processos de gestão de RH adotados na OAB/PI. Utilizou-se como metodologia um estudo de caso. A coleta de dados foi realizada por meio de questionário estruturado no padrão Likert, contendo 30 afirmativas sobre as seis dimensões que integram o processo de gerenciamento de RH. O questionário foi aplicado a uma amostra composta por 53 funcionários da sede administrativa da instituição, localizada na cidade de Teresina (PI). Os resultados obtidos demonstraram que os colaboradores se sentem contemplados em vários aspectos das dimensões avaliadas, porém necessitam de uma gestão de pessoas mais participativa e comprometida com o desenvolvimento profissional, com incentivos e com reconhecimento pelo trabalho desenvolvido. A pesquisa permitiu identificar, a partir da percepção dos colaboradores, quais dimensões do processo de gestão de RH exigem intervenções, bem como indicar ações estratégicas que possam melhorar o desempenho da instituição no gerenciamento de pessoas.
Inimigo em comum: fatores de seleção para novos parceiros na colaboração com base nos filmes ‘vingadores’
Authors: Silva João Paulo Oliveira da , Castro Karla Giselle Silva de , Lins Emanuela Ribeiro , Xavier Filho José Lindenberg Julião
Published: May 2022

Neste artigo, consideraremos como organização o grupo de heróis da MARVEL denominado ‘Vingadores’. Após identificar na literatura critérios de seleção em Redes Colaborativas, foi considerada a importância dos critérios de seleção de cada novo membro na Rede, analisando um período de onze anos de existência (2012 a 2023). Os resultados baseados na análise fílmica inédita dos ‘Vingadores’ como Rede Interorganizacional, contribuem para identificar quais os critérios de seleção de novos parceiros dentro de uma estrutura colaborativa atuam nos sucessos e fracassos desses arranjos.
A lei 13.460/2017 em Sergipe e o papel do tribunal de contas do estado: plano de ação concebido a partir da análise situacional em unidades gestoras de Sergipe
Authors: Nascimento Vinícius de Souza , Silva César Henriques Matos e
Published: May 2022

A Lei 13.460/2017 representou notável avanço na proteção dos destinatários dos serviços públicos, com inovações essenciais à garantia da participação social, à defesa dos direitos dos cidadãos e à busca por uma prestação de serviços adequada, tais como: carta de serviços ao usuário, conselho de usuários de serviços públicos, avaliação continuada dos serviços públicos, canal de manifestações na ouvidoria pública e relatório de gestão anual da ouvidoria. O normativo é de grande relevância ao aprimoramento do controle social e à melhoria dos serviços públicos, o que está plenamente relacionado com as competências institucionais dos Tribunais de Contas. O presente estudo foi, então, conduzido com o objetivo de analisar como os poderes executivos existentes em Sergipe estão cumprindo as diretrizes da referida lei, visando delineamento de análise situacional e de propostas de encaminhamentos para o Tribunal de Contas do Estado. O referencial teórico foi desenvolvido a partir da análise de estudos relacionados à Lei 13.460/2017 e às Cortes de Contas. Em termos metodológicos, utilizou-se estratégia de estudo de caso único com múltiplas fontes de dados, mediante questionários enviados para prefeituras municipais que tiveram gestores reeleitos e Governo do Estado de Sergipe. Os resultados evidenciaram o funcionamento precário ou inexistente da maioria das inovações concebidas pela legislação e os obstáculos remanescentes à efetividade da legislação em comento. Em atenção à análise situacional e às relevantes competências constitucionais do Tribunal de Contas do Estado, foram, então, formatadas as propostas de encaminhamentos visando, com isso, possibilitar a plena realização das diretrizes constantes na norma entre as unidades administrativas jurisdicionadas da Corte de Contas Sergipana.
Avaliação de desempenho financeiro em bancos tradicionais e bancos digitais: um estudo de multicasos
Authors: Carvalho Josue de Lima , Furtado Flavia dos Santos , Ribeiro Michel Carvalho , Santos Ticiane Lima dos , Ferreira Ynis Cristine de Santana Martins Lino
Published: May 2022

A partir de 2015 houve um crescimento das chamadas fintechs, empresas de serviços financeiros que tem como base o modelo de negócio digital e hoje podem ser classificadas em diversos grupos, inclusive em Bancos Digitais. Visando identificar o impacto que os bancos digitais estão causando no mercado financeiro realizou-se uma análise comparativa de desempenho de bancos tradicionais e bancos digitais, com aplicação de indicadores de solvência, liquidez, capital, risco rentabilidade, lucratividade e eficiência operacional aos dados das demonstrações contábeis dos bancos analisados. Para ranquear e classificar essas instituições em eficientes e ineficientes utilizou-se a Análise Envoltória de Dados – DEA. Como resultados identificou-se que, em relação aos índices de solvência e liquidez, o banco digital Agibank atua com índices mais altos, quando comparado com todos os bancos, expressando que o banco atua com um nível de solvência e liquidez bem mais baixos que os demais. Por outro lado, os bancos Inter e Original preferem atuar com um nível um pouco maior de liquidez e solvência. Os índices de rentabilidade evidenciaram que não são os bancos com maiores valores em ativos ou patrimônio líquido que obtiveram melhor rentabilidade, e sim os bancos que tiveram índices maiores nos indicadores de solvência e liquidez.
C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9
Authors: Jauch-Speer Saskia-Larissa , Herrera-Rivero Marisol , Ludwig Nadine , Véras De Carvalho Bruna Caroline , Martens Leonie , Wolf Jonas , Imam Chasan Achmet , Witten Anika , Markus Birgit , Schieffer Bernhard , Vogl Thomas , Rossaint Jan , Stoll Monika , Roth Johannes , Fehler Olesja
Published: May 2022

The proinflammatory alarmins S100A8 and S100A9 are among the most abundant proteins in neutrophils and monocytes but are completely silenced after differentiation to macrophages. The molecular mechanisms of the extraordinarily dynamic transcriptional regulation of S100a8 and S100a9 genes, however, are only barely understood. Using an unbiased genome-wide CRISPR/Cas9 knockout (KO)-based screening approach in immortalized murine monocytes, we identified the transcription factor C/EBPδ as a central regulator of S100a8 and S100a9 expression. We showed that S100A8/A9 expression and thereby neutrophil recruitment and cytokine release were decreased in C/EBPδ KO mice in a mouse model of acute lung inflammation. S100a8 and S100a9 expression was further controlled by the C/EBPδ antagonists ATF3 and FBXW7. We confirmed the clinical relevance of this regulatory network in subpopulations of human monocytes in a clinical cohort of cardiovascular patients. Moreover, we identified specific C/EBPδ-binding sites within S100a8 and S100a9 promoter regions, and demonstrated that C/EBPδ-dependent JMJD3-mediated demethylation of H3K27me3 is indispensable for their expression. Overall, our work uncovered C/EBPδ as a novel regulator of S100a8 and S100a9 expression. Therefore, C/EBPδ represents a promising target for modulation of inflammatory conditions that are characterized by S100a8 and S100a9 overexpression.
A novel systematic byte substitution method to design strong bijective substitution box (S-box) using piece-wise-linear chaotic map
Authors: Ali Asim , Khan Muhammad Asif , Ayyasamy Ramesh Kumar , Wasif Muhammad
Published: May 2022

Cryptography deals with designing practical mathematical algorithms having the two primitive elements of confusion and diffusion. The security of encrypted data is highly dependent on these two primitive elements and a key. S-box is the nonlinear component present in a symmetric encryption algorithm that provides confusion. A cryptographically strong bijective S-box structure in cryptosystem ensures near-optimal resistance against cryptanalytic attacks. It provides uncertainty and nonlinearity that ensures high confidentiality and security against cryptanalysis attacks. The nonlinearity of an S-box is highly dependent on the dispersal of input data using an S-box. Cryptographic performance criteria of chaos-based S-boxes are worse than algebraic S-box design methods, especially differential probability. This article reports a novel approach to design an 8 × 8 S-box using chaos and randomization using dispersion property to S-box cryptographic properties, especially differential probability. The randomization using dispersion property is introduced within the design loop to achieve low differential uniformity possibly. Two steps are involved in generating the proposed S-box. In the first step, a piecewise linear chaotic map (PWLCM) is utilized to generate initial S-box positions. Generally, the dispersion property is a post-processing technique that measures maximum nonlinearity in a given random sequence. However, in the second step, the concept is carefully reverse engineered, and the dispersion property is used within the design loop for systematic dispersal of input substituting sequence. The proposed controlled randomization changes the probability distribution statistics of S-box’s differentials. The proposed methodology systematically substitutes the S-box positions that cause output differences to recur for a given input difference. The proposed S-box is analyzed using well-established and well-known statistical cryptographic criteria of nonlinearity, strict avalanche criteria (SAC), bit independence criteria (BIC), differential probability, and linear probability. Further, the S-box’s boomerang connectivity table (BCT) is generated to analyze its strength against boomerang attack. Boomerang is a relatively new attacking framework for cryptosystem. The proposed S-box is compared with the state-of-the-art latest related publications. Results show that the proposed S-box achieves an upper bound of cryptographic properties, especially differential probability. This work hypothesizes that highly dispersive hamming distances at output difference, generated a systematic S-box. The mixing property of chaos generated trajectories utilized for decimal mapping. To test the randomness of generated chaotic trajectories, a cryptographically secure pseudo-random sequence was generated using a chaotic map that was tested using the National Institute of Standards and Technology (NIST) NIST-800-22 test suit.
DeepNC: a framework for drug-target interaction prediction with graph neural networks
Authors: Tran Huu Ngoc Tran , Thomas J. Joshua , Ahamed Hassain Malim Nurul Hashimah
Published: May 2022

The exploration of drug-target interactions (DTI) is an essential stage in the drug development pipeline. Thanks to the assistance of computational models, notably in the deep learning approach, scientists have been able to shorten the time spent on this stage. Widely practiced deep learning algorithms such as convolutional neural networks and recurrent neural networks are commonly employed in DTI prediction projects. However, they can hardly utilize the natural graph structure of molecular inputs. For that reason, a graph neural network (GNN) is an applicable choice for learning the chemical and structural characteristics of molecules when it represents molecular compounds as graphs and learns the compound features from those graphs. In an effort to construct an advanced deep learning-based model for DTI prediction, we propose Deep Neural Computation (DeepNC), which is a framework utilizing three GNN algorithms: Generalized Aggregation Networks (GENConv), Graph Convolutional Networks (GCNConv), and Hypergraph Convolution-Hypergraph Attention (HypergraphConv). In short, our framework learns the features of drugs and targets by the layers of GNN and 1-D convolution network, respectively. Then, representations of the drugs and targets are fed into fully-connected layers to predict the binding affinity values. The models of DeepNC were evaluated on two benchmarked datasets (Davis, Kiba) and one independently proposed dataset (Allergy) to confirm that they are suitable for predicting the binding affinity of drugs and targets. Moreover, compared to the results of baseline methods that worked on the same problem, DeepNC proves to improve the performance in terms of mean square error and concordance index.
Combinations of action observation and motor imagery on golf putting’s performance
Authors: Lin Chi-Hsian , Lu Frank J.H. , Gill Diane L. , Huang Ken Shih-Kuei , Wu Shu-Ching , Chiu Yi-Hsiang
Published: May 2022

Motor imagery (MI) and action observation (AO) have been found to enhance motor performance, but recent research found that a combination of action observation and motor imagery (AOMI) together is even better. Despite this initial finding, the most effective way to combine them is unknown. The present study examined the effects of synchronized (i e.,concurrently doing AO and MI), asynchronised (i.e., first doing AO then MI), and progressive (first asynchronised approach, then doing synchronized approach) AOMI on golf putting performance and learning. We recruited 45 university students (Mage = 20.18 + 1.32 years; males = 23, females = 22) and randomly assigned them into the following four groups: synchronized group (S-AOMI), asynchronised group (A-AOMI), progressive group (A-S-AOMI), and a control group with a pre-post research design. Participants engaged in a 6-week (three times/per-week) intervention, plus two retention tests. A two-way (group × time) mixed ANOVA statistical analysis found that the three experimental groups performed better than the control group after intervention. However, we found progressive and asynchronised had better golf putting scores than synchronized group and the control group on the retention tests. Our results advance knowledge in AOMI research, but it needs more research to reveal the best way of combining AOMI in the future. Theoretical implications, limitations, applications, and future suggestions are also discussed.
Momentos transmodales durante el proceso de enseñanza de la escritura en educación remota de emergencia: prácticas culturales y semióticas
Authors:   Pontificia Universidad Católica de Valparaíso, Centro de Investigación para la Educación Inclusiva, Manghi Dominique , Jarpa Azagra Marcela ,   Pontificia Universidad Católica de Valparaiso (Chile), Morales Ibarra Grace ,   Pontificia Universidad Católica de Valparaiso (Chile), Montes Fredes Paula ,   Pontificia Universidad Católica de Valparaiso (Chile)
Published: May 2022

Profesoras/es y aprendices recrean significados constantemente, condicionados por los medios digitales usados en la enseñanza remota durante la pandemia. Los profesores diseñan significados como juegos de aprendizaje e involucran a los estudiantes en la simulación de prácticas culturales, en las cuales las secuencias didácticas de escritura se materializan en cadenas que desplazan los significados entre diversos modos semióticos, dando origen a momentos transmodales. Este estudio integra tres enfoques teóricos: socio-semiótico, antropológico-didáctico y didáctico-disciplinar. Nuestro objetivo es explorar la semiosis en los momentos transmodales ocurridos en la interacción virtual durante una secuencia didáctica. Desde lo cualitativo, este estudio de caso profundiza en la simulación de prácticas culturales de una estudiante de 4o año de educación básica mediante el análisis integrado de cadenas semióticas y SHTIS (Sistema-Híbrido-Texto-Imagen-Sonido). Los hallazgos ofrecen una descripción de los juegos de aprendizaje vinculados con dos prácticas culturales cuyos núcleos de significado se desplazan entre seis eslabones. El rastreo de núcleos refleja la tensión entre la agencia de ambos creadores, que se materializa en ensamblajes semióticos de la enseñanza y aprendizaje mediados a través de una plataforma digital, en la que destaca el reciclaje de videos y documentos. No obstante, la retroalimentación revela que los significados visuales siguen invisibilizados.
El videojuego como recurso educativo: estudio de las actitudes de los docentes en República Dominicana
Authors:   Instituto Superior de Formación Docente Salomé Ureña (República Dominicana), Weisz Vilma Rafaelina Gerardo , Marcelo Carlos ,   Universidad de Sevilla (España)
Published: May 2022

Los videojuegos forman parte de la vida cotidiana de los estudiantes. Sin embargo, no siempre se consideran como recursos educativos dentro de los procesos de enseñanza. El propósito de este estudio fue analizar las actitudes que tienen los docentes del nivel inicial primario y secundario de la República Dominicana en relación con el uso de los videojuegos como recurso educativo. Para ello, se empleó una metodología de tipo cuantitativo no experimental con un diseño exploratorio-descriptivo, aplicando un análisis factorial exploratorio con SPSS y uno confirmatorio con AMOS. Los resultados muestran que los profesores más jóvenes, que han usado alguna vez los videojuegos, presentan una mayor disposición a incorporarlos en el aula que aquellos que nunca los han usado ni se han capacitado en su uso. Lo anterior crea barreras que limitan la incorporación de estos juegos en el aula, lo que implica una necesidad urgente de formación de los docentes de los grados estudiados en este ámbito.
Evaluación diagnóstica inicial en la formación inicial docente en Chile y su relación con contextos institucionales
Authors:   Universidad de O’Higgins, Universidad de Chile, Giaconi Valentina , Gómez Gabriela ,   Instituto de Ciencias de la Educación, Universidad de O’Higgins, Jiménez Daniela ,   Departamento de Evaluación, Medición y Registro Educacional, Universidad de Chile, Gareca Benjamin ,   Instituto de Ciencias de la Educación, Universidad de O’Higgins, Durán del Fierro Francisco ,   University College London, Varas María Leonor ,   Universidad de Chile
Published: May 2022

En este artículo se estudia la implementación, en cinco universidades chilenas, de una ley que mandata la aplicación de una evaluación diagnóstica inicial en las carreras de pedagogía. La ley indica que los resultados de esta evaluación serán referenciales y tendrán un uso formativo para los estudiantes; asimismo, da autonomía a las universidades para definir qué y cómo evaluar. Considerando la importancia de esta evaluación y su alcance, el objetivo de este artículo es entender cómo se implementan estas evaluaciones y cómo su aplicación se relaciona con el contexto de cada institución. La metodología utilizada corresponde al estudio de casos y los datos analizados corresponden a entrevistas a representantes institucionales, al análisis de las evaluaciones efectuadas y a sus resultados psicométricos. Se concluye que los aspectos contextuales más importantes para definir las evaluaciones diagnósticas fueron las capacidades técnicas y los recursos a los que pudieron acceder las escuelas de pedagogía y se observó una desarticulación con los perfiles de ingreso o programas formativos.
Alfabetización emergente: tipos de creencias de un grupo de profesores de educación preescolar y especial en Chile
Authors:   Universidad Católica de la Santísima Concepción (Chile), Manosalba Torres Consuelo Fernanda , Arancibia Gutiérrez Beatriz Magaly ,   Universidad Católica de la Santísima Concepción (Chile)
Published: May 2022

Diversas investigaciones muestran que las creencias docentes son un importante factor explicativo de las prácticas de enseñanza. No obstante, en países latinoamericanos aún son escasos los estudios sobre las concepciones docentes en torno a la alfabetización emergente y a los factores que intervienen en ella. Por eso, esta investigación analiza las creencias de un grupo de docentes sobre alfabetización emergente y su relación con el ambiente de aprendizaje en el aula y con uno de los factores intervinientes menos estudiado: el contexto sociofamiliar. La indagación fue cualitativa, con enfoque psicofenomenológico, y se realizó mediante entrevistas en profundidad. El análisis mostró que el tipo de creencia predominante es no sofisticada, con características no cognitivas que derivan desde saberes provenientes de un discurso basado principalmente en el modelo coconstructivista de la alfabetización. Asimismo, mediante el software NVivo, se determinó que el discurso de las participantes no supera el 13% de alcance en cada categoría de análisis.
Actitudes y capacidades de los docentes frente a la innovación educativa. La mirada de los estudiantes
Authors:   Universidad Católica de la Santísima Concepción (Chile), Constenla Nùñez Jaime Aroldo , Vera Sagredo Angélica Jeannette ,   Universidad Católica de la Santísima Concepción (Chile), Jara-Coatt Pilar Andrea ,   Universidad Católica de la Santísima Concepción (Chile)
Published: May 2022

Esta investigación buscó determinar las actitudes y capacidades de los docentes frente a la innovación educativa desde la percepción de 828 estudiantes de 19 establecimientos educacionales de la región del Biobío, Chile. Para dar respuesta a las preguntas de investigación, se realizaron análisis comparativos de diferencias de medias a través de ANOVA, prueba t y las correlaciones mediante el coeficiente de Pearson. Los principales resultados muestran que el profesorado en general es bien valorado respecto de las características de un docente innovador, especialmente en lo relativo al respeto (84,7%), la disposición (86,9%), el compromiso (82%) y la vocación (81,1%). Sin embargo, se evidenciaría una menor apreciación en el uso de herramientas tecnológicas, como el correo electrónico y las redes sociales, para el apoyo en los procesos de enseñanza-aprendizaje. Asimismo, las mujeres tendrían una valoración mayor en algunas características del profesorado vinculado con las relaciones interpersonales. Finalmente, las correlaciones mostraron una relación positiva y significativa de las variables examinadas con respecto al género de los estudiantes.
Tele-Audiology in India: Current and Future Trends in Knowledge, Attitude, and Practice Among Audiologists
Authors: M R Nazreen Nihara , Seethapathy Jayashree
Published: May 2022

Background and Objectives: The COVID-19 pandemic has led to widespread use of telepractice in hearing health care services. In this study, we investigated the knowledge, attitude, and practice (KAP) of tele-audiology among Indian audiologists. The current study is based on tele-practice guidelines recommended by the Indian Speech and Hearing Association for tele-audiology services in India. Subjects and Methods: An internet-based KAP questionnaire survey was performed among 108 audiologists. The questionnaire included 33 items categorized under the following domains: demographic information and KAP of tele-audiology. Of the 108 audiologists included in the study, 38 admitted to the practice of tele-audiology previously and during the COVID-19 pandemic (tele-practitioners), and 70 respondents had no experience of tele-audiology (non-telepractitioners). Results: Overall higher scores were observed with regard to the knowledge domain, and a mixed attitude regarding tele-practice was observed among audiologists. Most respondents acknowledged the advantages of tele-audiology in clinical practice. However, audiologists were hesitant to utilize this technology owing to the challenges associated with tele-practice. Conclusions: Despite adequate awareness and a positive attitude, a gap is observed between available knowledge and its actual application/utilization in tele-audiology. Tele-audiology practice was limited to counseling, hearing impairment treatment, and troubleshooting tips for hearing aids. Evidence-based practices to perform diagnostic test battery in tele-mode, hands-on training to run diagnostic test battery/rehabilitation using a tele-mode approach, and greater understanding of the technical requirements for tele-practice may result in a positive perception and encourage tele-audiology practice among audiologists. Specialized training and regular continuing education programmes are important to promote tele-audiology services in clinical practice.
Comparison Study of Neighborhood Structures in Local Search for Vehicle Routing Problem with Multiple Trips and Time Windows
Authors: Kenaka Saskia Puspa , Suprayogi Suprayogi
Published: May 2022

This paper deals with the vehicle routing problem with multiple trips and time windows (VRPMTTW). The problem combines two features to the basic vehicle routing problem (VRP): multiple trips and time windows. The basic VRP and its variants fall into hard combinatorial optimization problems. Therefore, many heuristics have been developed to solve large problems. Local search (LS) is one of the heuristics using a neighborhood structure in order to find a better solution. This paper focuses on the comparative study of neighborhood structures applied in LS for the VRPMTTW. Two classes of neighborhood structures are compared: Tour-based and permutation-based neighborhood structures. The tour-based neighborhood structures are the neighborhoods in which the moves are performed on the solution represented by a set of tours. The permutation-based neighborhood structures are the neighborhood structures in which the moves are carried out on the solution represented by a permutation of customers. Comparing the performance of the neighborhood structures uses two responses: (1) relative improvement in the objective function value and (2) computation time. The first response is used to measure effectiveness, while the second is used as efficiency. Based on the computational experiment results, it is generally revealed that the permutation-based neighborhood structures used in LS are more effective than the tour-based neighbourhood structures. However, the permutation-based neighborhood structures are less efficient because they give higher computation times.
Solving Multi-Objective Paired Single Row Facility Layout Problem Using Hybrid Variable Neighborhood Search
Authors: Maghfiroh Meilinda Fitriani Nur
Published: May 2022

The footwear industry is distinguished by its manual assembly line and a high proportion of shared workstation configuration. This study focuses on a subset of the single row facility layout problem known as the paired single row facility layout problem. As one of type of single-row facility layout, the paired single row facility layout problem cannot be solved quickly. Further, different objectives also need to be considered in the decision-making process. Therefore, multi-objective approaches are proposed to minimize the penalty of material handler usage while maximizing the adjacency function based on each workstation's closeness rating. A Single Row Facility Layout is an NP-hard problem; this problem also belongs to the NP-hard problem class. As a result, we propose a hybrid method combining variable neighborhood search (VNS) and genetic algorithm (GA) to solve the problem of obtaining the optimal configuration of a multi-objective paired single-row assembly line. A heuristic approach was used to create the schematic representation solution. To obtain the neighborhood solutions, a hybrid VNSGA was used. The schematic representation solution employs crossover and variable neighborhood descent. Using the concept of VNS, the neighborhood was changed in each generation.
High Mass Loading 3D‐Printed Sodium‐Ion Hybrid Capacitors
Authors: Yuan Jun , Qiu Min , Chen Jun Xiang , Hu Xiang , Liu Yangjie , Yu Biao , Zhong Guobao , Weng Zixiang , Zhan Hongbing , Wen Zhenhai
Published: May 2022

Sodium‐ion hybrid capacitors (SIHCs) have been regarded as one of the promising energy devices thanks to its low cost and compromise between energy density and power density, yet remain a challenge towards practical levels of mass loading (>10 mg cm−2). Herein, the fabrication of a 1D core–shell structure is reported with N‐doped porous carbon encapsulating ZnV2O4 nanofibers (ZnV2O4NFs@N‐PC), which features an open framework and favorable properties for facilitating ion diffusion, mass transportation, and electron transfer, enabling it to perform impressively for sodium ions storage. A 3D printed SIHC is conceptually proposed by coupling the 3D printed ZnV2O4NFs@N‐PC anode with a 3D printed active carbon cathode, which can deliver a high energy/power density of 145.07 Wh kg−1/3677.1 W kg−1 with a durable cycling lifespan. It is demonstrated that the 3D printed SIHC, even at a high mass loading of up to 16.25 mg cm−2, can release a high areal energy/power density of 1.67 mWh cm−2/38.96 mW cm−2, outperforming most of the SIHCs developed so far. The present work sheds light on the role of the design of electrode materials and verifies the promise of 3D‐printed technology for next‐generation electrochemical energy devices.
Low Surface Accessible Area NanoCoral TiO2 for the Reduction of Foreign Body Reaction During Implantation
Authors: Zhang Fanyu , Qi Haoning , Mo Wenting , Ni Yueqi , Zhao Qin , Wang Yulan , Jiang Shuting , Tang Qinchao , Cheng Yihong , Xiao Xiangheng , Zhang Yufeng
Published: May 2022

The entry of implants triggers the secretion of damage associated molecular patterns (DAMPs) that recruit dendritic cells (DCs) and results in subsequent foreign body reaction (FBR). Though several studies have illustrated that the surface accessible area (SAA) of implants plays a key role in the process of DAMPs release and absorption, the effect of SAA on the immune reaction still remains unknown. Here, a series of TiO2 plates with different SAA is fabricated to investigate the relationship between SAA and FBR. Compared with larger SAA surface, the aggregation of DC is significantly inhibited by lower SAA surface. Total internal reflection microscopy (TIRFM) and molecular dynamic (MD) simulation show that although high mobility group box 1 (HMGB1) is adsorbed more on plates with lower SAA, the exposure ratio of cysteine (CYS) residue in HMGB1 is significantly decreased in lower SAA group. The lower exposure of CYS reduces the activation of Toll‐like receptors 4 (TLR4), which down‐regulates the expression of myeloid differentiation factor (Myd88)‐TNF receptor associated factor 6 (TRAF6) to inhibit nuclear factor kappa B (NF‐κB) signaling. Generally, this study reveals the mechanism of how SAA, a nanoscale property, affects FBR from perspective of DAMPs, and provides a new direction for designing better biocompatible implants.