bluuebunny/crossref_metadata_2025 huggingface dataset:
An Audit of Gynecological Surgeries Performed at the University College Hospital, Ibadan, Southwest Nigeria
Authors: Salufu Stephen , Adewumi Bankole A. , Olayemi Oladapo O.
Published: September 2024

Abstract

Background:

Audit in a clinical setting is the collection of data for the purpose of setting professional standards, assessing clinical performances and modifying the clinical practice which is not routinely done in developing countries, including Nigeria. Audit of gynecologic surgeries in University College Hospital (UCH), Ibadan, was necessary to provide opportunities for improvement.

Objectives:

To determine the total number of gynecologic surgeries performed at UCH, the commonest surgeries performed at the hospital; and the cadres of surgeons who performed the surgeries especially the lead surgeons.

Materials and Methods:

This was a descriptive retrospective study of gynecologic surgeries carried out at the obstetrics and gynecology department of UCH, Ibadan, over a 5-year period. Data collected from theater records were entered into SPSS 24.0 software, cleaned and analysis performed.

Results:

There were 3790 gynecologic surgeries during the review period, in which outpatient gynecologic surgeries (surgical day or minor cases) accounted for the majority 53% (n = 2007), while major gynecological surgeries accounted for 47% (n = 1783). Cervical biopsy was the commonest surgical day (minor) procedure (541/2007, 27%), while abdominal myomectomy (517/1783, 29%) was the most performed major gynecologic surgery. Resident doctors performed most of the minor procedures, 73.7% (1476/2003), while the consultants led majority of the major procedures, 73.2% (1399/1910).

Conclusion:

A high number of gynecological surgeries were performed at UCH, Ibadan, under the period of review. Cervical biopsy and abdominal myomectomy were the commonest performed minor and major cases, respectively. Most minor cases were performed by Resident doctors while consultants performed most of the major cases. The high number of surgical cases performed could be an indication of the effectiveness of the healthcare delivery and training in the hospital.
Clinical Profile and Histopathological Pattern of Major Salivary Gland Tumors in a Nigerian Tertiary Hospital
Authors: Akpeh James O. , Nze Uchechukwu C. , Ezeanolue Basil C.
Published: September 2024

Abstract

Background:

Varieties of tumors can arise from major salivary glands primarily or secondarily. Over 30 histological subtypes have been documented by the World Health Organization, serving as a guide in diagnosis and management.

Objectives:

To evaluate the clinical and histological pattern of presentation of major salivary gland tumors.

Materials and Methods:

This is a clinical retrospective study, done at the University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria, assessing records of patients with major salivary gland tumors seen between January 2018 and December 2022. Data obtained were analyzed using Statistical Package for Social Sciences version 26. The results were presented in tables and charts and comparisons were made using the Chi-squared test.

Results:

Out of the 57 patients with major salivary gland tumors studied, 30 (52.6%) were benign tumors, and 27 (47.4%) were malignant tumors. About 63.2% of patients were predominantly females, whereas 36.8% were males with a male-to-female ratio of 1:1.7. The most common presenting symptom was swelling. The average duration of symptoms before presentation was 24 and 12 months for benign and malignant tumors, respectively. The parotid gland (61.4% total) was the most common site of tumor presentation for both benign and malignant tumors followed by the submandibular and sublingual the least. The most common histological variant was pleomorphic adenoma (40.4%) for benign and mucoepidermoid carcinoma (28.1%) for malignant. Surgery was the first line of treatment given.

Conclusion:

The observed pattern of clinical and histological presentation of major salivary gland tumors will guide clinicians on the approach for the management.
Prevalence and Pattern of Urinary Tract Obstruction in Patients with Urolithiasis in Southeast Nigeria
Authors: Onuh Augustine C. , Anyimba Solomon K. , Mbadiwe Okezie M. , Amu Okwudili C. , Nnabugwu Ikenna I. , Mgbor Samuel O.
Published: September 2024

Abstract

Background:

Urolithiasis is a global problem and its prevalence is steadily increasing. This trend is also true in tropical and sub-Saharan Africa. Urinary tract obstruction is a common complication of untreated urolithiasis. Data on the prevalence and pattern of this obstruction are limited in the literature.

Objectives:

The objective of this study is to determine the prevalence and pattern of urinary tract obstruction in patients with urinary stone disease.

Materials and Methods:

This is a retrospective study carried out over 9 years between April 2013 and June 2022. Records of patients who had abdominopelvic computerized tomography scans done at Hansa Clinics Enugu were retrieved for this study. From the medical records, the age and gender of the patients were extracted. The pattern and degree of obstruction noted on the imaging were recorded. Data were described using frequencies and proportions in tables and graphs. Analysis was done using Statistical Package for Social Sciences for Windows, version 26.0.

Results:

Out of 2467 subjects reviewed, urinary tract stones were identified in 356 subjects (14.4%). The mean age of the subjects was 49 ± 15.7 years. The majority were males (57.0%). In those with urinary tract obstruction, the majority had hydronephrosis (67.9%) followed by hydroureter (43.0%) and pelvocaliectasis (37.6%).

Conclusion:

Urinary tract obstruction with stones is common, and often associated with hydronephrosis and hydroureter. Therefore, early detection and management using relevant imaging techniques will go a long way in reducing the burden of renal failure which is a serious possible sequelae.
Alexithymia in Parents of Children with Neurodevelopmental Disorder: A Cross-Sectional Comparative Study
Authors: Alauddin Norah Mohammed , Anbarasu D.
Published: September 2024

Background:

Emotional insight is the distinctive core factor of human characteristics and it is so basic and foundational for every aspect of human understanding, communication, and daily care of life. Recent studies have identified that children with neurodevelopmental disorders (NDD) and their relatives have difficulties in identifying and recognizing their own emotions.

Objectives:

The present study was aimed to investigate the level and comparison of alexithymia scores in parent of autism, attention deficit hyperactivity disorder (ADHD), and typically developing children (TDC).

Study Design:

A cross-sectional comparative study.

Methods:

One hundred and fifty (N = 150) parents were recruited into the study which includes parents of 50 autism, parents of 50 ADHD, and parents of 50 TDC by means of convenience sampling method. Toronto Alexithymia Scale-20 was used to measure alexithymia in parents of NDDs.

Results:

The study revealed that there was a statistically significant difference in Alexithymia scores between parents of children diagnosed with autism spectrum disorder (ASD), attentiondeficit hyperactivity Disorder (ADHD), and typically developing children (One-Way ANOVA: F = 133.497, P < 0.001). Parents of children with ASD scored significantly higher on Alexithymia (66.26±4.575, t = 6.05172, 95% CI: 64.96 to 67.56) than parents of children with ADHD (59.02±7.116, t = 8.8296, 95% CI: 57.00 to 61.04) and typically developing children (49.36±3.036, 95% CI: 48.50 to 50.22). No significant association was found in Alexithymia scores with respect to gender in children against their parents (P = 0.267). Similarly, no significant association was found in Alexithymia scores with respect to demographic variables of child’s age, child’s gender, and parental age (P = 0.064).

Conclusion:

The results suggest that alexithymia has higher impacts on parents of autism and there is a growing need of necessary focus on alexithymia an important issue in parents of children with NDDs. Thus, it is very essential to treat alexithymia with special focus.
The Status of Access to Medicines and Enrollment in Welfare Schemes by Rural Elderly People of Southerner Rajasthan
Authors: Vasant Jadhav Abhijeet , Shilpa H Bhakare
Published: September 2024

Introduction:

Multiple layers of vulnerability pose challenges for rural elderly to access health. Enrollment in government schemes is also limited by this section of society. This study focused on access to medicines and status welfare schemes for rural elderly.

Subjects and Methods:

It was a cross-sectional survey done in 84 villages in six districts of Rajasthan with 1266 elderly participants. The data were captured through a pretested questionnaire which was filled by trained data collectors.

Results:

The knowledge, as well as the actual enrollment of the elderly in various health care and welfare schemes, was very poor. Gender and caste analysis showed that women and lower castes were at the worst end in the enrollment and availing entitlements. Knowledge of health schemes was also less among them. The monthly average expenditure for participants on regular medication was Rs. 1570.35 and the time to procure the same was 6.10 h.

Discussion:

The elderly are vulnerable to the worst health outcomes and gender and cast categories add to it. Access to medicines is an essential component of health accessibility. However, it is largely neglected. Money and time in accessing required medicines seem to be too high to afford for these elderly people. Limited availability of public health facilities, poverty in old age, and the absence of private pharmacies in villages have contributed to the problem significantly. Welfare schemes have the potential to address these issues; however, enrollment and actual reach of benefits still need to be improved in rural areas.
Atypical Eclampsia: Revisited
Authors: Shaikh Shabista , Bal Himadri , Lal Swati
Published: September 2024

ABSTRACT

Obstetrics is always full of surprises and challenges. Some of these shake us up and make us hunt the literature to convince ourselves that such a thing exists and makes us wiser. Here we report a case where a 3rd gravida presented with classical features of eclampsia and HELLP syndrome at 18 weeks of gestation defying the criteria of gestational hypertension and its sequelae presenting only after 20 weeks. The pregnancy was successfully managed on recommended guidelines. Review of literature confirmed the not so common presentation of eclampsia at such early gestation when it is designated as atypical eclampsia. The atypicality may be in the form of gestational age of presentation or clinical features that do not adhere to the classical definition of pre-eclampsia/eclampsia. The purpose of this case report is to make ourselves aware of the entity of atypical eclampsia that will enable us to zero down on the diagnosis at the right time and plan subsequent management.
Temporal Association Between COVID-19 Immunoglobulin-G Antibody Induced Focal Cerebral Arteriopathy and New-Onset Acute Ischemic Stroke in a Pediatric: Is it Causal or Coincidental?
Authors: Suryawanshi Vaibhav R. , Momin Sarosh , Kalrao Vijay , Raut Asawari
Published: September 2024

ABSTRACT

Focal cerebral arteriopathies, vasculitis, microangiopathies, coagulopathies, and in-situ microthrombi leading to territorial infarction of neural tissues are some of the most recent instances which are reported as a consequence of the infection caused by the novel coronavirus (SARS-CoV-2). Acute ischemic stroke (AIS) is one of the major neurological manifestations that have been linked with COVID-19. We describe a case of a 5-year-old boy who had an acute-onset of bilateral arm and leg weakness due to a posterior circulatory ischemic stroke that was temporally associated with COVID-19 Immunoglobulin-G antibody-induced cerebral arteriopathies and vasculitis. Laboratory examination was suggestive of elevated D-dimer levels to 3302 ng/ml, elevated C-reactive protein to 10 mg/dl, and elevated fibrinogen levels to 433 mg/dl. He had a negative COVID-19 nasopharyngeal polymerase chain reaction and positive COVID-19 serologies. Focal cerebral arteriopathy and AIS were managed by administering early antithrombotics, steroids, and multivitamins. On routine follow-ups, the patient remained free from new neurological and functional deficits. Although many hypotheses are proposed to explain the causal relationship between the two, it could as well be sheer coincidence.
Management of a Case of Airway Edema after Shoulder Arthroscopy
Authors: Patra Arun K. , Dube Mallikarjun , Mishra Satish K. , Dubey Mayank , Choudhury Ipsita
Published: September 2024

ABSTRACT

Arthroscopic shoulder surgeries are routinely practiced in many orthopedic centers for diagnostic and therapeutic purposes. The patient is commonly made to lie in a lateral position to carry out the procedure. We had a 71-year-old patient who underwent right shoulder arthroscopy for rotator cuff injury; the duration of surgery was 300 min. The patient developed subcutaneous edema over the neck and anterior chest. Further evaluation revealed airway edema as well. The patient was shifted to ICU for monitoring and overnight ventilation. Other radiological investigations confirmed the edema in subcutaneous and deep tissues of the neck and chest. The patient was extubated the next day morning after the edema improved. She was shifted to the ward for further management. Airway edema after shoulder arthroscopy, though uncommon, can be predicted in susceptible patients with prolonged surgeries and excess fluid irrigation. Timely diagnosis and intervention with coordination among the treating teams can result in positive outcomes.
Millennial Generation’s Choice of Contact Lens as the Preference Over Spectacles: A Study of Corneal Endothelial Cell Density
Authors: Mishra Neeta , Prasad Neelam , Chotalia Rekha , Bajare Uday , Madan Veshal V.
Published: September 2024

ABSTRACT

Introduction:

The cornea of the eye is the most vulnerable organ to external insult. Contact lens is no exception. Changes in corneal epithelium, stroma, and loss of hexagonal shape in the endothelium have been taught in contact lens classes. We wanted to understand the cell density of endothelium in prolonged contact lens wear.

Methods:

It was a prospective, observational, cross-sectional study. The volunteers were divided into two groups: group 1 wore their contact lenses for over 5 years and group 2 never wore contact lenses. Specular microscopy was performed using Topcon SP-3000P. Computerized morphometry was used to evaluate the mean cell density of the corneal endothelial cells.

Result:

A statistically significant decrease in corneal endothelial cell density was observed in contact lens wearers.

Conclusion:

The use of contact lenses for a prolonged period significantly decreases corneal endothelial cell density. Suitable intervention may prevent such changes in the cornea.
The Evaluation of Enterprise Carbon Trading Audit Based on DSR Model and GHG Accounting
Authors: Chen Dongsheng
Published: September 2024

INTRODUCTION: With the continuous development of social economy, environmental issues are becoming increasingly apparent. How to maintain the coordination of environmental and economic development is an urgent issue to be addressed. This study takes carbon trading as an example, starting with enterprise CAE, proposes a CAE index system that combines DSR model and GHG accounting, and hopes to urge enterprises to reduce carbon emissions during development.OBJECTIVES: Carbon audit is an important way to evaluate the low carbon development of enterprises. To effectively realize the evaluation of enterprise carbon audit, the study takes cement enterprises for instance and proposes a carbon audit evaluation (CAE) standard.METHODS: Firstly, it adopts the greenhouse gas (GHG) accounting method to monitor the carbon release of cement companies, and secondly, the main factors are analyzed based on the data obtained from the monitoring, and then the driving-force state-response (DSR) index system is constructed to realize the evaluation of carbon trading audit of cement enterprises.RESULTS: The results show that the accuracy of the adopted carbon emission monitoring method is 99.3%, which is significantly higher than the other methods, and the error is only 0.1 after stabilization. Finally, after the CAE, we can see that the CAE method proposed by the study is reasonable and feasible with the actual situation with a fit of 0.954, which means that the evaluation method proposed by the study is reasonably practicable.CONCLUSION: It is necessary to combine the DSR model with the GHG accounting approach to conduct the enterprise CAE, which can improve the enterprise CAE system and is of great value to the improvement of the efficiency of the enterprise CAE.
Characteristics of the imaging diagnosis of alveolar echinococcosis
Authors: Aydin Sonay , Irgul Baris , Memis Kemal Bugra , Kızılgoz Volkan , Kantarci Mecit
Published: September 2024

Alveolar echinococcosis (AE) primarily manifests in the liver and exhibits characteristics resembling those of slow-growing malignant tumours. Untreated Echinococcus multilocularis infection can be lethal. By infiltrating the vascular systems, biliary tracts, and the hilum of the liver, it might lead to various problems. Due to its ability to infiltrate neighbouring tissues or metastasize to distant organs, AE can often be mistaken for malignancies. We present a concise overview of the epidemiological and pathophysiological characteristics of AE, as well as the clinical manifestations of the disease. This article primarily examines the imaging characteristics of AE using various imaging techniques such as ultrasonography, computed tomography (CT), magnetic resonance imaging, diffusion-weighted imaging, and virtual non-enhanced dual-energy CT. We additionally examined the contribution of radiography in the diagnosis, treatment, and monitoring of the condition.
Personalized treatment of perihilar cholangiocarcinoma based on tumor genetic and molecular characteristics
Authors: Tang He-Nan , Wang Ming-Wei , Liu Xue-Song , Jiao Yan
Published: September 2024

This editorial discusses the article written by Tchilikidi et al that was published in the latest edition of the World Journal of Gastrointestinal Surgery . Genetic and molecular profiling of perihilar cholangiocarcinoma (pCCA) has identified a number of key abnormalities that drive tumor growth and spread, including pyruvate kinase M2, proline rich 11, and transcription factor 7, etc . pCCA has specific genetic and molecular features that can be used to develop personalized treatment plans. Personalized treatment approaches offer new opportunities for effectively targeting the underlying drivers of tumor growth and progression. The findings based on tumor genetic and molecular characteristics highlight the importance of developing personalized treatment strategies.
Effect of smoking on the risk of gastrointestinal cancer after cholecystectomy: A national population-based cohort study
Authors: Kim Minseob , Han Kyung-Do , Ko Seung-Hyun , Woo Yoonkyung , Han Jae Hyun
Published: September 2024

BACKGROUND

The role of smoking in the incidence of colorectal cancer (CRC) or gastric cancer (GC) in populations undergoing cholecystectomy has not been investigated.

AIM

To evaluate the effect of smoking on CRC or GC development in cholecystectomy patients.

METHODS

A total of 174874 patients who underwent cholecystectomy between January 1, 2010 and December 31, 2017 were identified using the Korean National Health Insurance Service claims database. These patients were matched 1:1 with members of a healthy population according to age and sex. CRC or GC risk after cholecystectomy and the association between smoking and CRC or GC risk in cholecystectomy patients were evaluated using adjusted hazard ratios (HRs) and 95%CIs.

RESULTS

The risks of CRC (adjusted HR: 1.15; 95%CI: 1.06-1.25; P = 0.0013) and GC (adjusted HR: 1.11; 95%CI: 1.01-1.22; P = 0.0027) were significantly higher in cholecystectomy patients. In the population who underwent cholecystectomy, both CRC and GC risk were higher in those who had smoked compared to those who had never smoked. For both cancers, the risk tended to increase in the order of non-smokers, ex-smokers, and current smokers. In addition, a positive correlation was observed between the amount of smoking and the risks of both CRC and GC.

CONCLUSION

Careful follow-up and screening should be performed, focusing on the increased risk of gastrointestinal cancer in the cholecystectomy group, particularly considering the individual smoking habits.
The effect of intraoperative goal-directed fluid therapy in patients under anesthesia for gastrointestinal surgery
Authors: Zhang Jun , Li Xiao-Wen , Xie Bing-Feng
Published: September 2024

BACKGROUND

Intraoperative fluid management is an important aspect of anesthesia management in gastrointestinal surgery. Intraoperative goal-directed fluid therapy (GDFT) is a method for optimizing a patient's physiological state by monitoring and regulating fluid input in real-time.

AIM

To evaluate the efficacy of intraoperative GDFT in patients under anesthesia for gastrointestinal surgery.

METHODS

This study utilized a retrospective comparative study design and included 60 patients who underwent gastrointestinal surgery at a hospital. The experimental group (GDFT group) and the control group, each comprising 30 patients, received intraoperative GDFT and traditional fluid management strategies, respectively. The effect of GDFT was evaluated by comparing postoperative recovery, complication rates, hospitalization time, and other indicators between the two patient groups.

RESULTS

Intraoperative blood loss in the experimental and control groups was 296.64 ± 46.71 mL and 470.05 ± 73.26 mL (P < 0.001), and urine volume was 415.13 ± 96.72 mL and 239.15 ± 94.69 mL (P < 0.001), respectively. The postoperative recovery time was 5.44 ± 1.1 days for the experimental group compared to 7.59 ± 1.45 days (P < 0.001) for the control group. Hospitalization time for the experimental group was 10.87 ± 2.36 days vs 13.65 ± 3 days for the control group (P < 0.001). The visual analogue scale scores of the experimental and control groups at 24 h and 48 h post-surgery were 3.38 ± 0.79 and 4.51 ± 0.86, and 2.05 ± 0.57 and 3.51 ± 0.97 (P < 0.001), respectively. The cardiac output of the experimental and control groups was 5.99 ± 1.04 L/min and 4.88 ± 1.17 L/min, respectively, while the pulse pressure variability for these two groups was 10.87 ± 2.36% and 17.5 ± 3.21%, respectively.

CONCLUSION

The application of GDFT in gastrointestinal surgery can significantly improve postoperative recovery, reduce the incidence of complications, and shorten hospital stays.
Preoperative systemic inflammatory response index as a prognostic marker for distal cholangiocarcinoma after pancreatoduodenectomy
Authors: Zhang Wen-Hui , Zhao Yu , Zhang Cheng-Run , Huang Jin-Can , Lyu Shao-Cheng , Lang Ren
Published: September 2024

BACKGROUND

The relationship between preoperative inflammation status and tumorigenesis as well as tumor progression is widely acknowledged.

AIM

To assess the prognostic significance of preoperative inflammatory biomarkers in patients with distal cholangiocarcinoma (dCCA) who underwent pancreatoduodenectomy (PD).

METHODS

This single-center study included 216 patients with dCCA after PD between January 1, 2011, and December 31, 2022. The individuals were categorized into two sets based on their systemic inflammatory response index (SIRI) levels: A low SIRI group (SIRI < 1.5, n = 123) and a high SIRI group (SIRI ≥ 1.5, n = 93). Inflammatory biomarkers were evaluated for predictive accuracy using receiver operating characteristic curves. Both univariate and multivariate Cox proportional hazards analyses were performed to estimate SIRI for overall survival (OS) and recurrence-free survival (RFS).

RESULTS

The study included a total of 216 patients, with 58.3% being male and a mean age of 65.6 ± 9.6 years. 123 patients were in the low SIRI group and 93 were in the high SIRI group after PD for dCCA. SIRI had an area under the curve value of 0.674 for diagnosing dCCA, showing better performance than other inflammatory biomarkers. Multivariate analysis indicated that having a SIRI greater than 1.5 independently increased the risk of dCCA following PD, leading to lower OS [hazard ratios (HR) = 1.868, P = 0.006] and RFS (HR = 0.949, P < 0.001). Additionally, survival analysis indicated a significantly better prognosis for patients in the low SIRI group (P < 0.001).

CONCLUSION

It is determined that a high SIRI before surgery is a significant risk factor for dCCA after PD.
Diagnostic value of serum vascular endothelial growth factor and interleukin-17 in primary hepatocellular carcinoma
Authors: Tian Qi , Zeng Hui , Lu Qi-Quan , Xie Hai-Ying , Li Yong
Published: September 2024

BACKGROUND

Despite significant advancements in the medical treatment of primary hepatocellular carcinoma (PHC) in recent years, enhancing therapeutic effects and improving prognosis remain substantial challenges worldwide.

AIM

To investigate the expression levels of serum vascular endothelial growth factor (VEGF) and interleukin (IL)-17 in patients with PHC and evaluate their diagnostic value while exploring their relationship with patients’ clinical characteristics.

METHODS

The study included 50 patients with confirmed PHC who visited Wuhan Hanyang Hospital from January 2021 to January 2022, and 50 healthy individuals from the same period served as the control group. Serum VEGF and IL-17 levels in both groups were measured by Enzyme-Linked Immunosorbent Assay, and their diagnostic value was assessed using receiver operating characteristic (ROC) curves. Pearson correlation analysis was performed to examine the relationship between serum VEGF and IL-17 levels. Pathological data of the PHC patients were analyzed to determine the relationship between serum VEGF and IL-17 levels and pathological characteristics.

RESULTS

Serum VEGF and IL-17 levels were significantly higher in the study group compared to the control group (P < 0.05). No significant association was observed between serum VEGF and IL-17 levels and gender, age, combined cirrhosis, tumor diameter, or degree of differentiation (P > 0.05). However, there was a significant relationship between clinical TNM stage, tumor metastasis, and serum VEGF and IL-17 levels (P < 0.05). Correlation analysis revealed a positive correlation between serum VEGF and IL-17 (P < 0.05). ROC analysis demonstrated that both serum VEGF and IL-17 had good diagnostic efficacy for PHC.

CONCLUSION

Serum VEGF and IL-17 levels were significantly higher in PHC patients compared to healthy individuals. Their levels were closely related to pathological features such as tumor metastasis and clinical TNM stage, and there was a significant positive correlation between VEGF and IL-17. These biomarkers may serve as valuable reference indicators for the early diagnosis and treatment guidance of PHC.
Efficacy and safety of B-ultrasound-guided radiofrequency ablation in the treatment of primary liver cancer: Systematic review and meta-analysis
Authors: Zhang Xiong , Zhu Hong-Yi , Yuan Ming
Published: September 2024

BACKGROUND

Primary liver cancer is one of the most lethal malignancies in the world. Traditional treatment methods have limitations in terms of efficacy and safety. Radiofrequency ablation (RFA) guided by B-ultrasound, as a minimally invasive treatment, has attracted increasing attention in the treatment of primary liver cancer in recent years.

AIM

To study the efficacy and safety of RFA were compared with those of traditional surgery (TS) for treating small liver cancer.

METHODS

At least 2 people were required to search domestic and foreign public databases, including foreign databases such as EMBASE, PubMed and the Cochrane Library, and Chinese databases such as the China National Knowledge Infrastructure database, China Biomedical Literature database, Wanfang database and VIP database. Controlled trials of RFA vs conventional surgery for small liver cancer were retrieved from January 2008 to January 2023. They were screened and evaluated according to the quality evaluation criteria in the Cochrane Handbook of Systematic Reviews. The meta-analysis was performed using RevMan 5.3 software.

RESULTS

A total of 10 studies were included in this study, including 1503 patients in the RFA group and 1657 patients in the surgery group. The results of the meta-analysis showed that there was no significant difference in 1-year overall survival between the two groups (P > 0.05), while the 3-year and 5-year overall survival rates and 1-year, 3-year and 5-year tumor-free survival rates in the surgery group were greater than those in the RFA group (P < 0.05). In terms of complications, the incidence of complications in the RFA group was lower than that in the surgery group (P < 0.05).

CONCLUSION

In terms of long-term survival, TS is better than RFA for small liver cancer patients. However, RFA has fewer complications and is safer.
Combined gastroscopic and laparoscopic resection of gastric metastatic adenosquamous carcinoma from lung: A case report
Authors: Lin Yin , Wu Yi-Long , Zou Dong-Dong , Luo Xiao-Long , Zhang Shi-Yan
Published: September 2024

BACKGROUND

Primary lung cancer is the leading cause of cancer-related death worldwide. Common metastatic sites include the brain, liver, bones, and adrenal glands. However, gastric metastases from lung cancer are rare. This case may be the first report of a combined gastroscopic and laparoscopic resection for gastric metastatic adenosquamous carcinoma (ASC).

CASE SUMMARY

We report a case of gastric metastasis from lung cancer. The patient was a 61-year-old Han Chinese female who first attended our hospital complaining of a persistent cough, leading to the diagnosis of advanced-stage lung adenocarcinoma. After more than four years of chemotherapy, the patient began to experience epigastric pain. Endoscopy was performed, and pathological examination of biopsy specimens confirmed that the gastric lesion was a metastasis from lung cancer. The lesion was successfully resected by combined gastroscopy and laparoscopy. Histopathological examination of the resected gastric specimen revealed ASC.

CONCLUSION

Gastric metastases from lung cancer are rare. Endoscopy, histological and immunohistochemical staining are useful for diagnosing metastatic lesions. Surgical management may provide extended survival in appropriately selected patients.
Rocky Mountain Spotted Fever in Mexico: A Call to Action
Authors: Álvarez-Hernández Gerardo , López-Ridaura Ruy , Cortés-Alcalá Ricardo , García Rodríguez Gabriel , Calleja-López J. R. Tadeo , Rivera-Rosas Cristian N. , Alomía-Zegarra José Luis , Brophy Maureen , Brito-Lorán Carina Berenice , del Carmen Candia-Plata Maria , Ceballos-Liceaga Santa Elizabeth , Correa-Morales Fabián , Dzul-Rosado Karla R. , Foley Janet , Galván-Moroyoqui José Manuel , Ganta Roman , Gutiérrez-Cedillo Verónica , Hernández-Milán Néstor Saúl , López-Pérez Andrés M. , López-Soto Luis Fernando , Martínez-Soto Juan Manuel , Mata-Pineda Ana Lourdes , Paddock Christopher D. , Ruiz-González Irma Leticia J. , Salinas-Aguirre Juan Edmundo , Salzer Johanna S. , Sánchez-Montes Sokani , Soto-Guzmán Adriana , Tamez-Rivera Óscar , Wagner David M. , Walker David H.
Published: September 2024

Rocky Mountain spotted fever (RMSF) is an ongoing public health crisis in Mexico, particularly in states bordering the United States. The national highest incidence and mortality of RMSF occur in this region, resulting in a case-fatality rate that ranges annually between 10% and 50%, primarily affecting vulnerable groups such as children, elderly adults, and persons living in poverty. Multiple biological, environmental, and social determinants can explain its growing presence throughout the country and how it challenges the health system and society. It is necessary to integrate resources and capacities from health authorities, research centers, and society to succeed in dealing with this problem. Through a scientific symposium, a group of academicians, U.S. health officials, and Mexican health authorities met on November 8–10, 2023, in Hermosillo, Mexico, to discuss the current situation of RMSF across the country and the challenges associated with its occurrence. An urgent call for action to improve national capacity against RMSF in the aspects of epidemiological and acarological surveillance, diagnosis, medical care, case and outbreak prevention, health promotion, and research was urged by the experts. The One Health approach is a proven multidisciplinary strategy to integrate policies and interventions to mitigate and prevent the burden of cases, deaths, and suffering caused by RMSF in Mexico.
Automatic Baud Rate Detection Process
Authors:   Truck Bus Control and Communications Network Committee
Published: September 2024

Define a process enabling network devices to detect the baud rate of a CAN Classic network as specified by physical layers SAE J1939-11, SAE J1939-14, or SAE J1939-15. The intent is to minimize or eliminate communication disruption between existing network devices. These networks only support Classical Base Frame Format (CBFF) and Classical Extended Frame Format (CEFF) Data Frames, as defined in ISO 11898-1:2015.

Baud rate detection on a SAE J1939 CAN FD network is not in scope, as SAE J1939-17 is currently the only SAE J1939 CAN FD physical layer option and specifies only one supported baud rate combination (500 kbit/s / 2000 kbit/s).
Accounting for the mechanical response of the cell membrane during the uptake of random nanoparticles
Authors: Iaquinta Sarah , Khazaie Shahram , Jacquemin Frédéric , Fréour Sylvain
Published: September 2024

In order to improve the efficiency of the delivery of cancer treatments to cancer cells, the cellular uptake of nanoparticles (NPs), used as drug delivery systems, is numerically investigated through a mechanical approach. The objective is to optimize the NP's mechanical and geometrical properties to enhance their entry into cancer cells while avoiding benign ones. In previous studies, these properties are modeled as constant during the process of cellular uptake. However, recent observations of the displacement of the membrane's constituents towards the region in the cell membrane where the uptake of the NPs takes place show that the mechanical properties of the membrane vary during this process. Reason for writing The important contribution of adhesion to the wrapping process is already well documented in literature. It is therefore crucial to model this parameter properly as the conclusions made with a constant adhesion model may not be accurate compared to reality. Methodology Based on the existing knowledge on the reaction of membrane constituents to interaction with NPs, a 3-parameter sigmoidal function, accounting for the delay, amplitude, and speed of the reaction, has been used to model the evolution of adhesion. A variance-based sensitivity analysis has then been performed in order to quantify the influence of these parameters on the outputs of the model. Results It was found that the introduction of a variable adhesion tends to alter the predictions of endocytosis of NPs. The contribution of the amplitude and delay is respectively 0.32 and 0.43 times as important as that of the NP's aspect ratio, which is the prominent parameter. The influence of the slope of the transition is the least important parameter and does not appear to contribute to endocytosis. Implications Hence, models of the cellular uptake of NPs should use a variable, instead of constant, adhesion in order a representative as possible of the behavior of the cell membrane. The predictions are different from those obtained using a model with constant adhesion.
PEMANFAATAN STATUS WHATSAPP SEBAGAI MEDIA PROMOSI UMKM OPAK SINGKONG (OPSI) DESA SUKAJADI
Authors: Jefri Ulfi , Rachman Aditya , Anwar Khaerul , Sukmawati Sri , Murtafakiyah Fatum
Published: September 2024

Micro, Small and Medium Enterprises (MSMEs) have an important role in driving the local economy. MSMEs are the main source of income for many individuals in rural areas such as Sukajadi Village. In the era of globalization and advances in information technology, micro, small and medium enterprises (MSMEs). The purpose of this Community Service is to promote OpSi MSMEs by utilizing social media as a promotional tool has become a crucial strategy for MSMEs to develop their market share. One popular and widely used platform is WhatsApp. This service team aims to investigate the use of WhatsApp Status as a promotional medium for OpSi MSMEs in Sukajadi Village.
The methods of implementing Community Service activities are as follows: (1) Observation and interview (2) Training / Assistance (3) discussion and question and answer. The results of the implementation of Community Service show that the effective use of WhatsApp Status can increase customer awareness of OpSi MSME products (Opak Cassava). Product sales also experienced a significant increase after the use of WhatsApp Status as a promotional medium. Although challenges in terms of understanding technology and limited access still exist, OpSi MSMEs in Sukajadi Village find tangible benefits in utilizing this platform to expand their market reach
PRAKTIK PENGGUNAAN MEDIA INTERAKTIF BERBASIS POWER POINT PADA PEMBELAJARAN MATEMATIKA DI KELAS X IPS 6 SMA NEGERI 1 CIRUAS
Authors: Umalihayati Umalihayati , Qonita Qonita , Dayurni Popi , Agustia Anita Fitri , Aini Suhilda , Trigunadi Trigunadi
Published: September 2024

One of the factors that affect the quality of education is the presentation of creative and innovative material, so it is necessary to have learning media that can attract students' learning interest, so that the learning atmosphere is more comfortable and fun. The media used by teachers is one of the processes that aims to achieve the objectives of learning mathematics and the process of conducting through various experiences that teachers create through the learning environment. Learning with the help of mass media increases students' direct participation in the learning process. This activity is carried out with the objectives of (1) Getting teachers used to using power points as interactive learning media, (2) Teaching students to be able to create interactive media based on power points (3) As one way to increase students' attraction to mathematics. The result of this activity is that students already know how to make interactive media based on power points.
PENDAMPINGAN PEMBUATAN PENIRIS MINYAK PADA USAHA MIKRO, KECIL, DAN MENENGAH (UMKM) JAMUR TIRAM DI DESA SUKALABA, KECAMATAN GUNUNG SARI, SERANG
Authors: Bahits Abdul , Kusuma Aria Cendana , Muttaqin Reihan , Wardani Lismayada , Sari Natalia , Nurfauzan Muhammad
Published: September 2024

Initiated one year ago, Mr. Syamsul started his business in transforming oyster mushroom to edible food, precisely crispy mushroom, located in Sukalaba, Gunungsari, Banten. It started by Mr. Syamsul by selling crispy mushroom that the raw materials were obtained from the profit he got. Along the way, when his sales increased, Mr. Syamsul experienced difficulties in obtaining raw materials to process. From these obstacles, Mr. Syamsul tried to produce his own raw materials, namely oyster mushroom cultivation. Besides harvesting for his own needs, it turns out that the oyster mushroom can be sold directly to local residents, collectors, vegetable sellers, and so on. Therefore, in this service activity, the author provided counseling and assistance in turning oyster mushrooms into more product variants, so that it has a higher selling value, such as crispy mushroom, mushroom popcorn, mushroom meatballs, and so on. In addition, the author also provided counseling on production management, financial management and marketing management. As concrete evidence, the author also provided training on how to make an oil Spinner (appropriate technology), as it was one of the problems (filtering the oil from crispy mushroom) to Mr. Syamsul as one of the owners of the oyster mushroom MSMEs in Sukalaba, Gunungsari, Serang, Banten
EMPOWERMENT PUBLIC BASED NATIONALITY DALAM KEGIATAN MEMERIAHKAN PERAYAAN HUT KE-79 RI DI KELURAHAN BULAKAN
Authors: Juhandi Juhandi , Nissa Vika Rahma Zein , Safitri Eti Nurhayati , Yap Victor , Agustin Nungki
Published: September 2024

The 79th anniversary of the Republic of Indonesia is an important event that marks the journey of the Indonesian nation for almost eight decades since independence. On this anniversary, various activities are carried out throughout Indonesia, ranging from flag ceremonies to traditional competitions involving people from all walks of life. Flag ceremonies held at national, provincial and local levels are the centerpiece of the celebration, as a symbol of respect for the heroes who have fought for independence. In addition, activities such as fun walks, carnivals, and traditional competitions also strengthen the sense of togetherness, nationalism, and mutual cooperation in the community. Overall, the 79th Indonesian Independence Day commemoration is not only a symbolic celebration of independence, but also a means to strengthen national identity, foster love for the country, and strengthen togetherness among Indonesian people. It is an important moment to reflect on the nation's journey, celebrate achievements, and renew commitment to face future challenges with a spirit of unity and cooperation.
BAKTI SOSIAL SKRINING MATA DAN OPERASI KATARAK GRATIS RS. AHMAD WARDI DAN DOMPET DHUAFA BERSAMA MAHASISWA KULIAH KERJA MAHASISWA (KKM)
Authors: Maulana Nova , Kusuma Jaka Wijaya , Faislah Atmam Ahmad , Firnanda Firnanda , Sulistia Ningrum , Lailatul Qodariyah Eli , Hanipah Hanipah , Belli Cahyani Imella , Arif Munajat Mohamad , Gafa Haikal Muhamad , Muhamad Suwandi , Algi Alviani Novi , Aida Safitri , Samsiah Nurhasanah , Lisya Gunawan Nazwa , Al Imam Khodimun Sayid , Fahruroji Fahruroji , Agus Salim
Published: September 2024

This free eye screening and cataract surgery social service activity is a tangible form of concern for Ahmad Wardi Hospital and Dompet Dhuafa, which collaborate with Student Work Lecture (KKM) students. The main goal of this activity is to help the underprivileged to get free access to eye health checks and treatments, especially for those who suffer from cataracts. Through eye screening, the medical team can detect vision problems early, while cataract surgery is given to patients who meet the criteria to improve their vision. KKM students play an important role in this activity, starting from helping with preparations, providing education to the community, to being directly involved in the implementation in the field. With this program, it is hoped that people can feel the improvement in the quality of life, especially in terms of eye health, as well as grow awareness of the importance of maintaining eye health and conducting early checkups.
aplicación de prohibiciones de contratar derivadas de un incumplimiento del licitador o contratista en el ámbito de las administraciones públicas
Authors: Doncel Rodríguez Consuelo
Published: September 2024

El presente trabajo tiene por objeto el examen de las prohibiciones de contratar recogidas en el art. 71.2 de la Ley 9/2017, de Contratos del Sector Público y que son aquellas que derivan de incumplimientos de las obligaciones impuestas por dicha Ley y por los Pliegos que rigen la licitación, por parte de los licitadores o contratistas. Se trata de incumplimientos que con relativa frecuencia se dan en la contratación pública, por lo que resulta necesario concretar un procedimiento a seguir y las medidas a adoptar para evitar que puedan volver a contratar con la Administración Pública aquellos contratistas o licitadores incumplidores con ésta, evitando así perjuicios indeseados a los intereses generales en materia de contratación pública.
Esopo y el urbanismo andaluz: comentario a la sentencia del Tribunal Constitucional 25/2024, de 13 de febrero, sobre la LISTA
Authors: Martín Valdivia Salvador María
Published: September 2024

En diciembre de 2021 se publicaba la Ley 7/2021, de impulso para la sostenibilidad del territorio en Andalucía (LISTA). En ella se adoptaban nuevos criterios normativos para la regulación del urbanismo y de la ordenación del territorio en esa comunidad autónoma. Una de las principales apuestas se centraba en la original propuesta de clasificación del suelo, que afectaba muy sensiblemente a las posibilidades de uso del suelo rústico. Eran propuestas audaces y disruptivas respecto del statu quo tradicional. Esa norma fue objeto de un recurso de inconstitucionalidad que se resolvió por sentencia del Tribunal Constitucional 25/2024, de 13 de febrero, que es el objeto de nuestro análisis. El resultado de su diagnóstico ha sido la confirmación del acomodo constitucional de la práctica totalidad de los preceptos impugnados, con ciertas excepciones relativas al régimen autorizatorio de los usos mineros en el suelo rústico, al tratamiento de las vías pecuarias afectadas por procesos de transformación urbanística y a la proscripción de ciertas viviendas en suelo rústico que se vieran vinculadas a usos extraordinarios en esa clase de suelo. El resto ha sido confirmado en su constitucionalidad por la sentencia referida. El plus de seguridad jurídica que ello comporta para el urbanismo andaluz es la consecuencia más significativa de esta resolución constitucional
Developments in world motor vehicle production and the future of hydrogen use in the automotive industry
Authors: Aydin Kadir , Aydin Alkim
Published: September 2024

This article provides an overview of World motor vehicle production and hydrogen utilization technologies for current and future use in the Automotive Industry. Hydrogen is the simplest and most abundant element in the Universe; however it is always combined with other elements. Still, the costs of hydrogen production from its combined elements remain high compared to other energy sources; it is extremely difficult to store onboard, the use of natural gas as a feedstock emits CO2, and there are many technical challenges to overcome with these systems. Many years of research and development, as well as changes to the energy infrastructure, may be required before hydrogen can have a significant impact on Earth energy use. In the very long term, electricity and hydrogen are likely to become the preferred complementary energy vectors. Hydrogen and the fuel cell are complementary and each enables the other. Nowadays, due to their low production costs, hydrogen engines are becoming more and more advantageous over fuel cells and are be-coming more widespread. Ammonia has the potential to be used as a hydrogen carrier, mainly due to its high hydrogen capacity. A significant effort would be needed to develop onboard ammonia cracker systems or direct ammonia fuel cells for vehicles.
Uso de la ia aplicada en la enseñanza aprendizaje en biología bt, de la unidad educativa mocache caso Ecuador
Authors: Suárez Graciela Elizabeth Mora , Ibarra Juana Dolores Carriel , Lara Alejandro Reigosa , Farias Galo Wilfrido Tobar
Published: September 2024

El estudio aborda la influencia del uso de la Inteligencia Artificial (IA) en la enseñanza y aprendizaje en Biología dentro de la Unidad Educativa Mocache, Ecuador. El objetivo principal fue evaluar de qué manera la personalización en el aprendizaje y la evaluación automatizada, facilitadas por la IA, influyen en la percepción de los estudiantes sobre el rendimiento académico. Utilizando una metodología mixta y un diseño no experimental, se aplicaron encuestas a 40 estudiantes. Los hallazgos destacaron que la facilidad de integración de la IA (coeficiente 0.458, p = 0.001) y la adecuación de la infraestructura tecnológica (coeficiente 0.233, p = 0.029) tienen un impacto positivo significativo. No obstante, las inquietudes relacionadas con la privacidad de los datos (coeficiente -0.218, p = 0.026) mostraron un impacto negativo. Estos resultados indican que la IA tiene el potencial de mejorar el rendimiento académico si se abordan adecuadamente las preocupaciones éticas y se mejora la infraestructura tecnológica.