bluuebunny/crossref_metadata_2025 huggingface dataset:
Key Knowledge and Skills For Tourism Graduates: A Study in the Dominican Republic For All-Inclusive Hotels
Authors: Domínguez-Valerio Cándida María , Orgaz-Agüera Francisco
Published: January 2025

Objective: This study identifies the knowledge and skills tourism graduates need for leadership roles in all-inclusive hotels in the Dominican Republic, using insights from hotel managers to guide academic and professional training.
 
Theoretical Framework: Drawing on global research on tourism education and management, the study emphasizes the alignment of academic programs with industry needs, highlighting essential competencies such as leadership, sustainability, and technological proficiency.
 
Method: A qualitative case study was conducted using semi-structured interviews with 11 hotel managers in Puerto Plata. Data were analyzed through content analysis to identify recurring themes and patterns.
 
Results and Discussion: Findings underscore the importance of a bachelor’s degree in tourism, practical training, and postgraduate specialization in hotel management. Essential knowledge includes customer service, marketing, technology, sustainability, and data management. Key skills include decision-making, leadership, adaptability, and teamwork. The results highlight gaps in current academic curricula, emphasizing the need for universities to incorporate emerging topics like artificial intelligence and sustainable practices.
 
Research Implications: The study provides actionable insights for academic institutions to redesign tourism programs, fostering a workforce aligned with the dynamic needs of the all-inclusive hotel industry.
 
Originality/Value: This research fills a gap in the literature by focusing on the Dominican Republic’s all-inclusive hotel sector, offering a region-specific perspective that informs global discussions on tourism education and workforce development.
Value Co-Destruction, an Integrative Model Application of The Consolidated Meta-Analytical Approach
Authors: Aravena-Aranda Claudio , Valenzuela-Fernández Leslier , Mariano Ari Melo
Published: January 2025

Objective: The objective of this study is to investigate the evolution of  value co-destruction (VCD), developing an integrative model based on a thorough review and analysis of the literature from 1975 to 2023.
 
Theoretical Framework: This research is contextualised within the fields of marketing and service ecosystems, addressing concepts and theories that underpin the study, such as value Co-creation, Value Co-destruction, Service-dominant logic, and Consumer behaviour, providing a solid foundation to understand the research context.
 
Method: We employ the Theory of the Consolidated Meta-analytical Approach (TEMAC) and quantitative bibliometric techniques to analyse data extracted from the Web of Science and Scopus databases. Our systematic review was guided by the PRISMA framework, and we used VosViewer 1.6.5 visualisation software to construct bibliometric networks.
 
Results and Discussion: Value Co-destruction represents a significant risk to the sustainability and excellence of service delivery across all types of ecosystems.
 
Research Implications: The research shows how interactions between the various actors in a service ecosystem (users, service providers, and other stakeholders) can lead to negative and unsatisfactory outcomes, resulting in losses of both tangible and intangible resources for at least one of the involved actors.
 
Originality/Value: TEMAC provides a structured method useful for researchers in various fields, allowing an understanding of the past, present, and future in the investigated area through a replicable, systematic, and integrative literature review. From our integrative model, we can reflect that the evolution of Value Co-destruction has taken a winding path, where clear directions are still not visible in terms of concepts, theories, and consensus in the scientific community.
Reuse of Greywater and Rainwater in Health Units: Case Study in Upas in the Municipality of São Gonçalo
Authors: Silva Alice Marina de Lima da , Costa Bianca Gomes , Machado Anna Virgínia Muniz , Carvalho Paulo André Souza , Farias Rodrigo Oliveira de
Published: January 2025

Objective: Evaluate water consumption in Emergency Care Units (UPAs) in the municipality of São Gonçalo, Rio de Janeiro, and propose measures for the reuse of rainwater and greywater to reduce potable water consumption (PWC) and mitigate the impact on drainage networks by repurposing them for non-potable uses.
 
Theoretical Framework: The topic aligns with Sustainable Development Goal (SDG) target 6.3, in accordance with public health institutions.
 
Methodology: The Nova Cidade and Pacheco UPAs, located in the municipality of São Gonçalo, provided construction data and monthly water consumption figures in collaboration with public agencies and private companies.
 
Results and Discussion: This article wants to understand the potential of the UPAs areas to reuse water consumption through a quantitative analysis. This survey ensures efficiency in the methods proposed for water reuse for non-potable purposes, consequently reducing water consumption.
 
Implications for Research: Demonstrates the potential for simple water reuse approaches, even in small healthcare units, as illustrated by the UPAs in this study.
 
Originality/Value: This article contributes to the academic community addressing issues related to water integrity, particularly on the topic of water reuse. It is innovative in presenting the reality of the municipality of São Gonçalo, located in the state of Rio de Janeiro, as a case study.
The Value of Ethical Leadership in Improving Service Delivery Amongst Senior Managers
Authors: Nzimakwe Thokozani Ian , Utete Reward
Published: January 2025

Objective: The purpose of the study is to explore the senior managers' perceptions towards ethical leadership behaviours and their significance to service delivery. The study sought to achieve the following objectives i) exploring the factors that contributed to ethical behaviours, ii) determining whether senior managers practised ethical leadership.
 
Theoretical Framework:  The current study is guided by the legal framework of South Africa. A comprehensive set of laws and policies has been put in place since the beginning of democracy in 1994 to ensure that the public sector is more accountable, financially viable, and able to provide services to all South African citizens.
 
Method: The study adopted a qualitative research approach, and semi-structured interviews were utilised to collect data from ten (10) senior managers at a municipality in South Africa. Thematic analysis was employed to analyse the data.
 
Results and Discussion: The findings of the study revealed that the municipal workforce did not consider ethical leadership necessary for service delivery.
 
Research Implications: The senior managers of the organisation should be provided with regular scheduling of workshops on ethics. The executive management should make sure all employees sign a pledge as a reminder to behave in line with the ethical principles.
 
Originality/Value: In South Africa, corruption and maladministration among leaders have been cited as significant challenges that negatively impact service delivery in local government. However, limited studies have been conducted on ethical leadership, especially in the public sector. Hence, this extends the existing literature on ethical leadership behaviours and service delivery.
Seguimiento y monitoreo a la crisis migratoria venezolana en la ciudad de Arauca-Colombia, asentamiento el Refugio. Análisis espacio-temporal entre 2015 y 2023
Authors: Hoyos-Mendoza Carlos Enrique
Published: January 2025

La migración venezolana ha ejercido impacto en la transformación socioespacial y demográfica del asentamiento El Refugio en la ciudad de Arauca, Colombia. Este fenómeno ha dado lugar a cambios en la configuración territorial, con un marcado aumento en la densidad demográfica y la creación de nuevos sectores habitacionales. El incremento exponencial de hogares en el asentamiento, que pasó de 108 en 2015 a 1.248 en 2023, refleja la magnitud de esta transformación. Sectores como el 20 de abril y Llano Alto experimentaron alto crecimiento, impulsado por la urbanización irregular, acelerada y no planificada. Este crecimiento demográfico ha estimulado el desarrollo económico local, con un florecimiento de emprendimientos comerciales, especialmente en el sector alimentario, y una expansión en sectores como la agricultura y la construcción. Sin embargo, este auge económico ha venido acompañado de desafíos, como la competencia en el mercado laboral y la presión sobre los servicios de salud y educación. Además, la rápida expansión urbana ha generado impactos ambientales preocupantes, como la deforestación y la sobreexplotación de recursos naturales, destacando la necesidad urgente de una planificación urbana y ambiental responsable y sostenible.
Prevalência de transtornos psiquiátricos em pessoas vivendo com HIV em uso de terapia antirretroviral: um estudo transversal
Authors: Barros Laura Galliano de , Quidigno Eduardo Alcantara , Von der Heyde Marcelo Daudt
Published: January 2025

Introdução: o desenvolvimento da terapia antirretroviral mudou o curso da infecção pelo HIV, apesar disso, o impacto psicossocial desse diagnóstico ainda influencia na saúde mental das pessoas que vivem com o vírus. Objetivos: avaliar a prevalência de transtornos psiquiátricos em pacientes soropositivos. Materiais e Métodos: estudo transversal a partir das entrevistas com pacientes soropositivos acompanhados em um ambulatório de infectologia, em Curitiba (PR). Foram coletados dados epidemiológicos e clínico-laboratoriais, e aplicados os questionários Mini International Neuropsychiatric Interview (M.I.N.I) e Questionário Breve da Qualidade de Vida da OMS (WHOQOF-abreviado). O estudo foi submetido e aprovado pelo Comitê de Ética em Pesquisas, com CAAE n° 70235123.0.0000.0020 e parecer de aprovação de número 6.134.965. Resultados: participaram 69 pacientes, cuja idade média foi de 48 ± 12,4 anos, com predomínio do sexo masculino (50,7%). Desses, 33 (47,8%) apresentaram algum transtorno psiquiátrico, sendo os transtornos mais prevalentes o transtorno depressivo e agorafobia. Nesse grupo de pacientes, percebeu-se um tempo menor que 12 anos de diagnóstico da infecção pelo HIV (p=0,026), maior uso de Efavirenz (p=0,047) e Tenofovir (p=0,048). Ainda, percebe-se uma pior avaliação da qualidade de vida, especialmente na avaliação geral, e nos domínios psicológico, social e ambiental, quando comparados ao grupo que não apresentou acometimento da saúde mental pelo questionário M.I.N.I. Outros parâmetros avaliados não parecem ter papel importante na gênese de transtornos psiquiátricos nesse grupo de pacientes. Conclusão: pacientes com HIV tem alta prevalência de doenças de ordem psíquica, e apresentam particularidades que influenciam em seu desenvolvimento, logo, é fundamental a avaliação integral desses pacientes, e a busca ativa por queixas de saúde mental.
A review on hyperuricaemia – A metabolic disease and its homoeopathic management
Authors: Verma Divya , Agarwal Nishi
Published: January 2025

Hyperuricaemia is a common health issue encountered in the daily clinical practice of a physician. The gradual increase in the incidence of hyperuricaemia across the world adds to the existing disease burden. The increased uric acid level for a prolonged period is linked to the development of various systemic and metabolic diseases such as hypertension, cardiovascular disorders, chronic renal disease, gout and nephrolithiasis. The conventional treatment of hyperuricaemia is based on urate-lowering therapy. Various studies have been done to understand the role of uric acid in the pathogenesis of such diseases. Studies conducted in the field of homoeopathy show the positive role of homoeopathic medicines in treating hyperuricaemia, which can be cost-effective and free from side effects. This article aims to focus on the pathogenesis of hyperuricaemia and the current trends regarding hyperuricaemia and its homoeopathic approach.
Effectiveness of homoeopathic remedy causticum in the treatment of trigeminal neuralgia - Two case reports
Authors: Chakravarthy Srigiri G. S. , Vinitha T. , Beegum Saliha
Published: January 2025

Trigeminal neuralgia (TGN), also known as tic douloureux, is a recurrent painful disorder of the trigeminal nerve characterised by lancinating shooting pain along the dermatomes of the trigeminal nerve triggered by routine activities such as talking, brushing and chewing. Although the reason is unknown, the most common cause is attributed to neurovascular compression by its surrounding structures. Many pharmacological approaches alleviate trigeminal pain for a shorter duration with prolonged harmful counter effects and the most successful treatment, such as microvascular decompression surgery, gives a series of risks of complications. Homoeopathy is known for its cost-effectiveness and safest among all the treatment modalities that stands foremost in relieving neuralgic conditions, including TGN. Here, two cases of TGN are totally relieved by potentised homoeopathic medicine causticum, showing the efficacy over other systems of treatment as measured by the Barrow Neurological Institute pain intensity score before and after treatment.
Kısa İngiltere Tarihi
Authors: Güler Ayşegül
Published: January 2025

Kısa İngiltere Tarihi kitabı önsözle başlayan, beş bölümü içeren ve sonuçlar başlığı kısmıyla sona eren bir kitaptır. Eser isminden de anlaşılacağı üzere İngiltere tarihine odaklanmaktadır. İngilizlerin tarih anlatımı, diğer unsurlarla etkileşimi, yakın oldukları gruplar ve onlarla ilişkileri tarihsel bir akış içerisinde günümüze kadar verilmiştir.
Основные практики реновации модернистских жилых кварталов в Западной Европе
Authors: Балухина Наталья Владимировна , Долгов Александр Владимирович , Гибадулина Альфия Равильевна
Published: January 2025

Статья посвящена изучению теоретических исследований и апробированных на практике стратегий по реновации модернистских жилых ансамблей Западной Европы. Проведен анализ наиболее значимых западноевропейских документов, на базе которых происходит эволюция теоретических основ и практических подходов к проблемам реновации модернистского наследия. Выполнен обзор ряда реализованных проектов.

The article is devoted to the study of theoretical researches and proven strategies for the renovation of modernist residential ensembles in Western Europe. The analysis of the most significant Western European documents, on the basis of which the evolution of the theoretical foundations and practical approaches to the problems of renovating the modernist heritage, is carried out. A review of a number of implemented projects is performed.
Развитие концепции «идеального» города в градостроительстве начала XX века
Authors: Мазаев Григорий Васильевич
Published: January 2025

В статье рассматривается изменение принципа создания «идеальных» планировок городов, характерного для XVIII - начала XIX века, он сменяется идеей «города-сада». В планировке «городов-садов» в начале XX века широко используются планировочные приемы «идеальных» городов. Показана цикличность формообразования планов, когда стремление к «идеальности» градостроительной формы сменяется ее утилитарностью. 1 Работа выполнена по плану ФНИ на 2019 г. при поддержке РААСН и Минстроя России в соответствии с Государственной программой Российской Федерации «Развитие науки и технологий» на 2013-2020 гг., Программой фундаментальных научных исследований государственных академий наук на 2013-2020 гг.

The article discusses a change in the principle of creating «ideal» layouts of cities, characteristic of the XVIII - early XIX centuries: it is replaced by the idea of a «garden city». In the planning of the «city-gardens» at the beginning of the 20th century, the planning methods of the «ideal cities» are widely used. The cyclical nature of the formation of plans is shown, when the striving for the «ideality» of the town-planning form is replaced by its utility.
Проблемы сохранения исторической застройки Харбина
Authors: Лава Дарья Андреевна
Published: January 2025

Исследование посвящено изучению современного состояния исторической среды Харбина с целью ее восстановления. Рассмотрены исторические объекты периода русского Харбина, архитектура типовых жилых домов и современные сооружения в районе Пристани. Приведен анализ китайского подхода к реставрации и реконструкции, строительству новых зданий в историческом районе. В ходе натурного исследования выявлены и обследованы исторические объекты, требующие восстановления. Приведены проектные предложения по реставрации старых зданий.

The study is devoted to the study of the current state of the historical environment of Harbin to restore it. Historical objects of the period of Russian Harbin, the architecture of typical residential buildings and modern buildings in the Pristan area are considered An analysis of the Chinese approach to restoration and reconstruction, the construction of new buildings in the historic district is given. Historical objects requiring restoration were identified and examined during a field study. Project proposals for the restoration of old buildings are given.
Архитектура деревянного модерна на Урале
Authors: Михайлова Людмила Гавриловна , Голобородский Михаил Венидимович
Published: January 2025

Статья посвящена формированию и некоторым особенностям архитектурных строений Урала, выполненных в стилистике специфического направления рубежа Х|Х-ХХ веков - деревянного модерна, на примере утраченных и сохранившихся строений деревянного модерна, их архитектурных особенностей и декоративного убранства. Исследования направлены на изучение формирования стилистики деревянного модерна на Урале, его многообразия и своеобразия, влияния столичных школ, северного и провинциального модерна на становление архитектуры деревянного модерна. Работа выполнена по плану ФНИ на 2019 г. при поддержке РААСН и Минстроя России в соответствии с Государственной программой Российской Федерации «Развитие науки и технологий» на 2013-2020 гг., Программой фундаментальных научных исследований государственных академий наук на 2013-2020 гг.
Методы повышения энергоэффективности жилых зданий Баку с использованием BIM-технологий
Authors: Керимова Айгуль Джавид кызы
Published: January 2025

Рассматривается энергоэффективность жилых зданий Баку и Апшерона. Использованы данные статистических исследований по повышению уровня энергоэффективности зданий. Изучен зарубежный опыт, связанный с повышением энергоэффективности в зданиях. С помощью технологии информационного моделирования (BIM) проведен анализ уровня энергопотребления двухэтажного дома в различных вариантах в зависимости от изменения ориентации и использования солнечных батарей.

The article studies the problem of energy efficiency of residential buildings in Baku and Absheron. The data of statistical studies on improving of energy efficiency are presented. Foreign experience has been studied to support energy efficiency measures in buildings. Using information modeling (BIM), an example of the energy consumption of a two-story house of different orientations, the use of vegetation around and the use of solar panels is shown.
Исследование влияния жесткости этажей на сейсмическую реакцию и надежность
Authors: Зайнулабидова Ханзада Рауповна
Published: January 2025

В работе исследовано влияние уровня жесткости этажей на сейсмическую реакцию и надежность многоэтажных зданий. Воздействие при этом задано в виде нестационарного случайного процесса с разными преобладающими периодами колебаний. Проведены динамические расчеты зданий высотой 9, 12 и 17 этажей, определены величины перемещений и перекосов этажей, оценено влияние жесткости этажей на характеристики сейсмической реакции. Методом статистических испытаний определены уровни надежности зданий разной этажности и жесткости при заданных предельном уровне перекоса этажей и преобладающем периоде колебаний грунтов. Показана возможность выбора показателя жесткости этажей здания при заданных параметрах землетрясения и уровней надежности.

The influence of the level of rigidity of floors on seismic reaction and reliability of multi-storey buildings is investigated. The effect is given in the form of a non-stationary random process with different prevailing oscillation periods. the dynamic calculations of buildings with a height of 9,12 and 17 storeys, the values of the displacements and distortions of floors, we have evaluated the influence of rigidity of floors on the characteristics of seismic response. By the method of statistical tests to determine the levels of reliability of buildings of different heights and stiffness for given maximum level of misalignment of the floors and the predominant period of oscillations of the soil. Shows the choice of the stiffness of the floors of the building, with preset parameters of earthquakes and reliability levels.
Слово редактора
Authors: Долгов Александр Владимирович
Published: January 2025

В детстве было легко впадать в состояние задумчивости. Идешь по лесу, и тысячи задорных «почему?» слетают с каждой ветки, путаются под ногами, вдыхаются полной грудью. И ответы на них были какие-то радостные, светлые, окрыляющие, радужно окрашенные, словно солнечные зайчики.Иногда в полной безмятежности просто приходили в голову мысли - бестелесные сущности, словно ангелы. В голове от них становилось просторнее и светлее.Со временем весь этот мысленный простор накрыло силовое информационное поле. Под воздействием внешних сил мысли стали цепенеть, образовывать друг с другом структуры, позволяющие им самосохраниться и заявить об индивидуальном видении мира, о собственной точке зрения на происходящее.Приятно отметить, что именно с такими личностями читатели нашего журнала могут встретиться на его страницах. Избегая тривиальности и шаблонов, они спешат поделиться своими открытиями и мыслями.Желаю всем увлеченного чтения и раздумий за пределами силового информационного поля!
ПРОСТРАНСТВЕННОЕ РАЗВИТИЕ БОЛЬШОГО ЕКАТЕРИНБУРГА И ЕГО ЛИМИТИРУЮЩИЕ ФАКТОРЫ
Authors: Литовский Владимир Васильевич
Published: January 2025

В статье рассмотрены проблемы пространственного развития Екатеринбурга и его лимитирующие факторы. Приоритетное внимание уделено планам формирования Большого Екатеринбурга. На основе количественной модели «квадратуры круга» для описания пространственного развития Екатеринбурга с учетом численности его населения, показаны ограничения на размер Большого Екатеринбурга. * «Исследование выполнено при финансовой поддержке РФФИ и Правительства Свердловской области в рамках научного проекта № 20-49-660009»
ФОРМИРОВАНИЕ ОБЩЕСТВЕННОГО ПРОСТРАНСТВА ПРИ РЕВИТАЛИЗАЦИИ ИНДУСТРИАЛЬНЫХ ТЕРРИТОРИЙ В ЦЕНТРЕ НЕВЬЯНСКА
Authors: Буторина Дарья Григорьевна
Published: January 2025

Рассматривается вопрос ревитализации индустриальной территории на месте бывшего демидовского завода в центре Невьянска как стратегического направления развития города. Для решения задачи предлагается сформировать на месте промышленной зоны многофункциональное общественное пространство, дружественное к горожанам и гостям города. В соответствии с результатами проведенного опроса и потенциалом места выбраны методы преобразования промышленного центра, предложены проектные решения на основе отечественного и зарубежного опыта.

This article considers the question about the industrial territory on the site of the former Demidovsky plant in the center of Nevyansk as a strategic direction of the town development. In order to solve this problem, it is necessary to form a multifunctional public space on the site of the industrial zone, which is friendly to the citizens and guests of the city. According to the results of the social survey conducted and the potential of the place, the author chose methods of transformation of the industrial center, proposed design solutions based on domestic and foreign experience.
Прочность нормальных сечений изгибаемых элементов из поризованного бетона естественного твердения
Authors: Новиков Михаил Викторович , Чернышов Евгений Михайлович , Славчева Галина Станиславовна
Published: January 2025

Впервые исследована несущая способность нормальных сечений изгибаемых элементов из поризованного бетона класса В3,5÷В7,5 при действии кратковременных нагрузок и предложены приемлемые методы расчета с учетом фактических деформационно-прочностных характеристик бетона и арматуры. Установлено, что в нормально армированных сечениях балок наблюдается пластический тип разрушения, в переармированных - хрупкий, то есть разрушение происходит при недоиспользованной прочности арматуры и носит внезапный характер. Предложено пользоваться методикой СП 63.13330.2012 для расчета прочности нормальных сечений изгибаемых элементов из поризованного бетона естественного твердения. Наибольшие отклонения значений теоретической несущей способности балок от экспериментальных составляют 16%.

For the first time, the load-bearing capacity of normal sections of B3.5 class B7.5 curved concrete at short- term loads was investigated, and acceptable methods of calculation taking into account actual deformation and strength characteristics of concrete and reinforcement were proposed. It has been established that in normally reinforced sections of beams there is a plastic type of destruction, in reinforced - brittle, i.e. destruction takes place at underutilized strength of reinforcement and is sudden. It is proposed to use the procedure of SP 63.13330.2012 to calculate the strength of normal sections of bending elements made of porous natural hardening concrete. The greatest deviations of the values of theoretical bearing capacity of beams from experimental ones are 20%.
THE ROLE OF THE PIYAL CLERKS OF THE SOLOVETSKY MONASTERY IN THE PURCHASE OF SEA VESSELS FOR THE SOLOVETSKY FLEET (END XVI – 70s XVII)
Authors: Bogomazova A.A.
Published: January 2025

The article is devoted to the role of Pyalsky usolie in the acquisition of large sea vessels (lodias) for the needs of the Solovetsky monastery. Founded in the XV century on the islands in the White Sea, the monastery needed sea vessels. During the XVI–XVII c. monastic fleet grew, reaching its heyday by the 30th of the XVII c. At the end of the XVI– first half of the XVII c. the monastery acquired sea vessels annually, it bought them, ordered their building, received them as contribution. However, the question of the acquisition of marine vessels by the Solovetsky monastery has not yet been specifically addressed in scientific research. The monastery acquired most of the lodias from the residents of the parishes along the river Onega. Based on the archival sources, the article exposes the leading role of the Pialsky service in acquiring lodias "for the monastic use" on the river Onega in the XVII century. It also reveals the names of the residents of the region, who dealt with the Piyal clerks in the orders for the making of boats or in purchasing ready-made ships. The article describes the process of buying ships as well. It shows that the acquired lodges both increased the Solovetsky fleet and were distributed among the continental salt mines which belonged to the monastery, replacing the old or unusable ships.

Статья посвящена роли Пияльского усолья в приобретении крупных морских судов (лодий) для нужд Соловецкого монастыря. Основанная в XV в. на островах в Белом море, обитель нуждалась в морских судах. На протяжении XVI–XVII вв. монастырский флот рос, достигнув своего расцвета к 30-м гг. XVII в. В конце XVI– первой половине XVII вв. обитель ежегодно приобретала морские суда: покупала, заказывала их изготовление, получала в качестве вклада. Однако вопрос о приобретении морских судов Соловецким монастырем до сих пор специально не поднимался в научных исследованиях. Большую часть лодий монастырь приобретал у жителей волостей по р. Онеге. На основе архивных источников установлена ведущая роль Пияльской службы в приобретении лодий «на монастырский обиход» на р. Онеге в XVII в., выявлены имена онежан, которым пияльские приказчики заказывали изготовление лодий или у которых покупали готовые суда, описан процесс покупки судов. В статье показано, что приобретенные лодьи не только увеличивали флот собственно монастыря, но и распределялись по материковым соляным промыслам обители, заменяли собой ветхие и вышедшие из строя суда.
HISTORY AND MODERN CONDITION OF THE SYSTEM OF TEACHING CHILDREN WITH HEARING DISORDERS IN THE REPUBLIC OF KAZAKHSTAN
Authors: Sivinsky A.M. , Kulambaeva K.K. , Kosherbaeva A.N.
Published: January 2025

The history of the development of special education is individual for each state. Despite the ongoing processes of globalization, involving a single educational space, in any country it has a significant impact on the approaches to teaching children with hearing impairments. Therefore, the successful construction of a national educational model cannot do without studying and understanding historical features. In this article, the authors explore the background, the main stages of the formation and the current state of the system of teaching hearing impaired and hearing impaired children in the Republic of Kazakhstan. A comparative analysis of the development of Surdopedagogical thought, starting from ancient times, is carried out. Variants of pedagogical influence on children experiencing problems with the perception of sound information are scientifically substantiated in antiquity, the Middle Ages and the new time based on the general characteristics of teaching methods in various historical periods, documentary and archival data. Using the retrospective method and the periodization method, the influence of political, social and economic factors on access to education of children with hearing impairment is considered. The historical features of the development of the Kazakh culture that influenced the special education system of Kazakhstan are revealed. The role of the Russian Empire and the USSR in the formation of the modern Kazakhstan network of schools for deaf and hearing-impaired children is considered.

История развития специального образования индивидуальна для каждого государства. Несмотря на непрерывные процессы глобализации, предполагающие единое образовательное пространство, в любой стране она оказывает существенное влияние на подходы к обучению детей с нарушениями слуха. Поэтому успешное построение национальной образовательной модели не может обойтись без изучения и понимания исторических особенностей. В данной статье авторы исследуют предпосылки, основные этапы становления и современное состояние системы обучения неслышащих и слабослышащих детей в Республике Казахстан. Проводится сравнительный анализ развития сурдопедагогической мысли, начиная с древнейших времен. Научно обосновываются варианты педагогического воздействия на детей, испытывающих проблемы с восприятием звуковой информации, в античность, средневековье и новое время с опорой на общую характеристику методов обучения в различных исторических периодах, документальные и архивные данные. Используя ретроспективный метод и метод периодизации, рассматривается влияние политических, социальных и экономических факторов на доступ к образованию детей с нарушениями слуха. Выявляются исторические особенности развития казахской культуры, оказавшие влияние на систему специального образования Казахстана. Рассматривается роль Российской империи и СССР в формировании современной казахстанской сети школ для неслышащих и слабослышащих детей.
Microbiome of pancreatic tumors
Authors:   PhD in Biology, junior researcher, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Fedorova M.S. , Pavlov V.S. ,   PhD in Biology,  junior researcher, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences (IMB RAS), Filatova A.A. ,   pathologist, Vishnevsky National Medical Research Center for Surgery of the Ministry of Health of the Russian Federation, Kalinin D.V. ,   Ph.D., Head of Pathology and Anatomy Department, Vishnevsky National Medical Research Center of Surgery, Ministry of Health of the Russian Federation
Published: January 2025

Pancreatic cancer is one of the most lethal types of malignancies, with a very low survival rate (5-7%), which is related to the difficulty of early diagnosis and the aggressive nature of the disease. The progression of tumours and the process of metastasis are linked to a number of factors, one of which is the tumour microbiome. The microbiota plays a role in the formation of an immune-tolerant environment, which contributes to cancer development by inducing angiogenesis, chemoresistance, immune cell suppression, tumour invasion and metastasis. Modifications in the composition of tumour-associated microbes and alterations in immune function may ultimately influence the progression and outcome of the disease. Enhancing our understanding of the composition and pathways of microorganisms in tumours, such as pancreatic cancer, will facilitate the identification of predictive factors and potential therapeutic targets. The objective of this review to synthesise the current knowledge about the composition of the microbiota and its origins in pancreatic tumours.
Keywords: microbiome, pancreatic cancer, tumour microenvironment
Динамическое ценообразование в недвижимости
Authors: Разумовский Л.Г. , Герасимова М.А. , Каренин Н.Е.
Published: January 2025

В работе рассматривается математическая модель динамической корректировки цены на недвижимость. Характеристиками модели выступают конечное число объектов недвижимости, фиксированный горизонт продаж, наличие промежуточных планов по продажам и выручке. В построенной модели рассмотрен случай переменного общего спроса, а также добавлен учет меняющейся со временем стоимости денег и роста цены объекта недвижимости по мере его строительной готовности. В работе изучен общий вид ценовой политики и представлен алгоритм нахождения цены в случае переменного общего спроса. Аналогичные построения проведены для модели, учитывающей стоимость денег и рост стоимости недвижимости по мере строительной готовности. Также рассмотрен случай линейной функции эластичности как базового, но в то же время наиболее распространенного случая ее практического использования. Приведены строгие математические доказательства полученных в работе результатов, а также выполнены численные симуляции с использованием реальных данных недвижимости в конкретном городе за 3,5 года с целью сравнения различных подходов к построению ценовой политики. Полученные результаты могут быть использованы для эффективного управления ценами на недвижимость.

The paper considers a mathematical model for dynamic price adjustment in real estate. The model is characterized by a finite number of real estate objects, a fixed sales horizon, and the presence of intermediate goals for sales and revenue. The model developed in this work addresses the case of variable total demand, incorporating the time value of money and the increase in real estate objects value as construction progresses. The general structure of pricing policy is studied, and an algorithm for determining prices under variable total demand is presented. Similar constructions are carried out for a model that accounts for the time value of money and the rising property value during construction. The case of a linear elasticity function is also examined as a basic but widely used practical scenario. Rigorous mathematical proofs of the results are provided, along with numerical simulations based on real estate data from a specific city over 3.5 years to compare different approaches to pricing policy formulation. The obtained results can be applied to effectively manage real estate pricing.
Functionalization of strained rings via nucleophilic catalysis
Authors: Deng Cheng , Wang Ping , Luo Zihao , Zhang Fangfang , Chen Ding , Liu Yuanqiang , Huang Lin , Yu Peng
Published: January 2025

Nucleophilic addition to strained rings offers a straightforward and effective strategy for synthesizing small aliphatic rings which serve a pivotal role as bioisosteres in medicinal research and drug development. However, incorporating sp³ C–H bonds into strained rings remains challenging due to their lack of electron lone pairs and weak acidity. Additionally, the frequent need for external stoichiometric bases or strong nucleophiles, such as organometallic reagents, presents issues related to practicality, compatibility, limited scope, and waste production. Here, we present a nucleophilic catalysis strategy that unlocks the nucleophilic addition of sp³ C–H bonds to strained rings and eliminates the need for an external stoichiometric base. This approach is also applicable to a wide range of heteroatom-based nucleophiles including carboxylic acids, amides, phosphine oxides, and thiols which typically require an external base for achieving reactivity in previously reported methods. Mechanistic studies suggest that this approach involves a covalent intermediate generated via the nucleophilic addition of the catalyst to the strained ring substrate, which serves as a key step in facilitating the reaction.
In pursuit of understanding metavalency
Authors: Chakkingal Parambil Priyakumari , Jhaa Gaurav , Kumari Mithu
Published: January 2025

The term metavalent bonding was introduced recently to describe bonds that are in between metallic and covalent. They are characterized by nearly half bond order, large Born Effective Charge (BEC), low band gap, moderate electrical conductivity and large optical dielectric constant. While the presence of large BEC, half-bond order and low band gap are often highlighted as their striking features, chemists are familiar with half-bond order systems, and hence there is a reluctance to consider metavalency as a new bonding mechanism. Here we use molecular orbital theory and DFT calculations to identify the uniqueness in the bonding in known metavalent materials and compare that with hypervalent half-bond order systems that are not classified as metavalent. We show that the metavalent materials are compounds with partial σ bonds that are formed mainly by p-p overlap and has low ionicity. If such systems have low band gaps either due to low bonding-antibonding splitting or due to delocalization, that result in large BEC. This suggests that metavalency is not a new bonding mechanism.
A Nitrilium-Type N-Heterocyclic Aryne
Authors: Alvarado Marisol , Tran Lauren , Li Bo , Darrigan Clovis , Preud'homme Hugues , Chrostowska Anna , Liu Shih-Yuan
Published: January 2025

The first solution-phase synthesis and reactivity of a nitrilium-type N-hetaryne are described. The 1,2-azaborine-derived 1,6-BN-aryne 2 exhibits [4+2], [3+2], and [2+2] cycloadditions and electrophilic aromatic substitution (EAS) reactivity. The observed regio- and diastereoselectivity of the cycloaddition and EAS products are consistent with a polarized aryne/nitrilium species. A Lewis structure description where the 1,6-BN-aryne 2 resonates between two limiting forms (ketenimine vs. nitrilium) is consistent with DFT calculations. New 1,2-azaborine structures that are functionalized at the C6- and N-positions, including highly strained derivatives that are previously not accessible, can now be accessed using 1,6-BN-aryne 2 as a versatile synthetic building block.
Photocatalytic Hydrophosphination Using Calcium Precatalysts
Authors: Moniruzzaman Moniruzzaman , Jheng Nai-Yuan , Waterman Rory
Published: January 2025

Hydrophosphination using calcium compounds as catalysts under irradiation is described as a foray into s-block photocatalysis. Transition-metal compounds have been highly successful hydrophosphination catalysts under photochemical conditions, utilizing substrates previously considered inaccessible. A calcium hydrophosphination precatalyst, Ca(nacnac)(THF)(N(SiMe3)2) (1, nacnac = HC[(C(Me)N-2,6-iPr2C6H3)]2), reported by Barrett and Hill, as well as the presumed intermediate, Ca(nacnac)(THF)(PPh2) (2), and the Schlenk equilibrium product, Ca[N(SiMe3)2]2(THF)2 (3) were screened under photochemical conditions with a range of unsaturated substrates including styrenic alkenes, Michael acceptors, and dienes with modest to excellent conversions, though unactivated alkenes were in accessible. All compounds exhibit enhanced catalysis under irradiation by LED-generated blue light. Nacnac-supported compounds generate radicals as evidenced by EPR spectroscopy and radical trapping reactions, whereas unsupported calcium compounds are EPR silent and appear to undergo insertion-based hydrophosphination akin to thermal reactions based. These results buttress the notion that photoactivation of -basic ligands is a broad phenomenon, extending beyond the d-block, but like d-block metals, consideration of ancillary ligands is essential to avoid radical reactivity.
A continuous flow generator of acetyl nitrate for the synthesis of nitrofuran-based pharmaceuticals
Authors: Hellwig Hubert , Bovy Loïc , Van Hecke Kristof , Vlaar Cornelis , Romañach Rodolfo , Noor-E-Alam Md. , Myerson Allan , Stelzer Torsten , Monbaliu Jean-Christophe
Published: January 2025

Nitrofurfural is a key building block for the synthesis of antimicrobial nitrofurans as active pharmaceutical ingredients. Its synthesis involves the nitration of furfural, a substrate derived from biobased resources. However, furfural has a delicate heteroaromatic backbone. Typical nitrations involve harsh reaction conditions, which often compromise this structure, resulting in poor reproducibility and low yields. Although acetyl nitrate, a mild nitrating agent, is suitable for this task, major deterrents remain. First, its conventional preparation method involves conditions that are not compatible with furfural. Second, significant safety concerns are associated with the unstable and explosive nature of acetyl nitrate. These critical issues are addressed herein. A safe and robust continuous flow platform featuring in situ generation of acetyl nitrate for the nitration of furfural to nitrofurfural is reported. The high level of integration and automation enables remote process operation by a single operator. Key furfural-based pharmaceutical intermediates were synthesized with favorable metrics and high reproducibility. The efficiency of this flow platform is demonstrated using a selection of best-selling nitrofuran pharmaceuticals (nifuroxazide, nifurtimox, nitrofurantoin and nitrofural), which were obtained with excellent isolated yields in under five minutes.
Using Yield Fingerprints to Study Reaction Mechanism
Authors: Duggal Kalyana B. , Moya Cruz Emmanuel , Jemison Adriana L. , Liu Yaning , DeCostanza Grace O. , Berlin Cameron B. , Piszel Paige E. , Zhu Weihao , Rotella Madeline E. , Kozlowski Marisa C.
Published: January 2025

Understanding reaction mechanisms can help to optimize efficiency, which allows industrially important molecules to be synthesized less expensively and more sustainably. Determining mechanisms, however, can be time consuming and resource-intensive. In this work, we outline an expeditious method to differentiate reaction mechanisms by means of unsupervised learning. With this technique, reaction “fingerprints” are created from the yields of a set of substrates subjected to several different reaction conditions. The resultant fingerprints are clustered by similarity to reveal mechanistic relationships. We have benchmarked this method with elimination reaction mechanisms, and used it to explore mechanistic relationships among C–H activation, phenol cross coupling, and amination catalysts. We determined that our method successfully categorizes elimination reaction mechanisms, as well as C–H activation reaction mechanisms between eCMD, CMD, and SEAr. Additionally, we found that due to the swift progress and discovery of new mechanisms in the C–H activation field, much of the C–H activation literature contains outdated mechanistic labels. Our method was able to correct these labels, and can be used to quickly hypothesize a mechanism for new C–H activation or amination catalysts with only 4-6 experiments. We also predicted potential similarities in phenol oxidative cross coupling catalysts that are mechanistically not well understood. Overall, this method has the potential to simplify the study of reaction mechanism for many types of reactions.
A new species of Bulbophyllum (Orchidaceae: Bulbophyllinae) section Macrocaulia from Sumatra, Indonesia
Authors: Yudistira Y.R , Candra R , Mustaqim W.A
Published: January 2025

Bulbophyllum bonjolianum Yudistira, Candra & Mustaqim, a member of section Macrocaulia, is described here based on a specimen collected from the mountains of West Sumatra. It is similar to B. tristriatum Carr. and B. pyridion J.J.Verm. but differs in the morphology of the dorsal sepal, petal and labellum. A key to B. bonjolianum and morphologically similar species is presented.
ESTIMATIVA DE EMISSÕES DE CO2 NA MOBILIDADE DO CORPO DISCENTE DA GRADUAÇÃO DO CEFET/RJ – MARACANÃ
Authors: Maciel Marcelo Sampaio Dias , Corrêa Fernando Ramos , Rodrigues Elizabeth Freitas , Nogueira Marcelo de Sousa , Queiroz Daniel da Costa , Figueiredo Pedro Soares
Published: January 2025

Objetivo: Este trabalho tem como objetivo quantificar as emissões de CO2 oriundas da locomoção dos estudantes do Cefet/RJ (Campus Maracanã) de seus domicílios ou locais de trabalho até a instituição, através de um questionário online.
 
Referencial Teórico: O referencial teórico aborda o crescimento urbano e seus impactos ambientais, destacando a importância de políticas eficazes para reduzir as emissões de CO2.
 
Método: Foi realizada uma pesquisa exploratória quantitativa utilizando um questionário online com oito questões fechadas e duas abertas. A análise revelou que aproximadamente dois quintos dos estudantes utilizam de dois a três modais de transporte para se locomover até a instituição, com o transporte rodoviário sendo o mais utilizado. As emissões totais semestrais de CO2 foram estimadas entre 172.884,5 kg e 199.760,1 kg.
 
Resultados e Discussão: A comparação entre os modais mostrou que o uso de transporte público resultaria em emissões significativamente menores em comparação ao uso de carros. Os resultados indicam a necessidade de políticas urbanas que incentivem o uso do transporte público coletivo e a educação ecológica dos estudantes. Este estudo é original ao quantificar as emissões de CO2 na mobilidade urbana dos estudantes de uma instituição de ensino público superior no Brasil.
 
Implicações da Pesquisa: Este estudo é original ao quantificar as emissões de CO2 na mobilidade urbana dos estudantes de uma instituição de ensino público superior no Brasil.
 
Originalidade/Valor: Ele oferece valor ao fornecer dados concretos que podem embasar políticas públicas e ações institucionais voltadas para a sustentabilidade e a redução de impactos ambientais.
Apresentação
Authors: Massmann Débora
Published: January 2025

Apresentação
The EU Pollinator Hub: Operationalisation of the EU Bee Partnership Platform for Harmonised Data Collection and Sharing Among Stakeholders on Bees and Pollinators
Authors: Noa Simon Delso , Santiago Otalora , Gregor Sušanj , Michael Rubinigg , Gilles San Martin
Published: January 2025

Abstract
The EU Pollinator Hub is an open‐source infrastructure that aims to standardise, collect, process, and visualise bee and pollinator‐related data from any relevant source hold by stakeholders. The Hub features an online collective approach to sharing harmonised data pertinent to bee and pollinator health monitoring. It provides an online platform with three basic functionalities, allowing the creation and growth of an online community focused on bee and pollinator health data. First, the Hub allows such a community to standardise terminology or promote existing standards, connecting them with uploaded datasets, thanks to its “Vocabulary”. Second, it helps users comply with Open Data principles, ensuring data uploaded in the Hub is FAIR (Findable, Accessible, Interoperable, and Reusable). Finally, the Hub serves as a repository for data peer‐reviewing, a pivotal process to verify the data quality, validity, and reusability of datasets made available by researchers, field practitioners, and institutional and industry stakeholders. The framework established by the EU Pollinator Hub allows datasets of varying nature, such as weather, landscape, and epidemiological data, to be analysed and processed together, providing a systems‐based approach to improve data interoperability.