bluuebunny/crossref_metadata_2025 huggingface dataset:
The role of corporate governance structures in mediating the relationship between external supervision, credit appraisal measurement, capital adequacy, and performance of commercial banks in Nepal
Authors: Bhatt Tribhuwan Kumar , Wang Wenli , Dang Xinghua , Jan Shahina Qurban
Published: June 2024

This study investigates the role of corporate governance structures as mediators between external supervision, credit appraisal measurement, capital adequacy, and the performance of commercial banks in Nepal. This research sheds light on the significance of effective corporate governance practices within Nepali commercial banks and how certain governance mechanisms may impact bank performance. A quantitative research design was employed, using data from commercial banks in Nepal for this study. Surveys were utilized to collect quantitative data. Structural equation modeling was used as a primary tool to assess the data. The findings add to existing literature about corporate governance and its effects on bank performance in emerging economies such as Nepal. The study’s findings offer valuable insights into the significance of corporate governance structures, external supervision, credit appraisal measurement systems, and capital adequacy for commercial banks’ performance in Nepal. The research methodology adds value to the existing literature using quantitative data collection methods. Its results may have practical ramifications for banks, regulators, and policymakers, suggesting effective governance practices as essential measures for increasing stability and performance at commercial banks.
Research on load clustering algorithm based on variational autoencoder and hierarchical clustering
Authors: Cai Miaozhuang , Zheng Yin , Peng Zhengyang , Huang Chunyan , Jiang Haoxia
Published: June 2024

Time series data complexity presents new challenges in clustering analysis across fields such as electricity, energy, industry, and finance. Despite advances in representation learning and clustering with Variational Autoencoders (VAE) based deep learning techniques, issues like the absence of discriminative power in feature representation, the disconnect between instance reconstruction and clustering objectives, and scalability challenges with large datasets persist. This paper introduces a novel deep time series clustering approach integrating VAE with metric learning. It leverages a VAE based on Gated Recurrent Units for temporal feature extraction, incorporates metric learning for joint optimization of latent space representation, and employs the sum of log likelihoods as the clustering merging criterion, markedly improving clustering accuracy and interpretability. Experimental findings demonstrate a 27.16% improvement in average clustering accuracy and a 47.15% increase in speed on industrial load data. This study offers novel insights and tools for the thorough analysis and application of time series data, with further exploration of VAE’s potential in time series clustering anticipated in future research.
Integrating design thinking and implementation science principles in delivering a medication review service in the community pharmacy setting—An implementation testing study
Authors: Mustafa Maali , Hatah Ernieda , Makmor-Bakry Mohd
Published: June 2024

Background

Medication review (MR) services are evidenced-based practices in which a systematic assessment of a patient’s medication is conducted, primarily aiming to optimize drug therapy and minimize adverse drug events through pharmacist interventions. Although studies show that MR services are effective, the implementation of MR services in Malaysia has been challenging due to several barriers. An MR services blueprint was developed to be adapted to the Malaysian community pharmacy setting as part of tailoring strategies.

Objective

Through utilizing the design thinking triple diamond model and implementation science principles, a powerful guide for healthcare researchers and stakeholders to assist with effective service implementation, this study aimed to evaluate the implementation testing and observe the effectiveness of the developed MR service blueprint.

Method

The study utilizes an effectiveness-implementation Type 3 hybrid implementation science framework conducted from May 2021 to April 2022. Employing a qualitative ethnographic approach, researchers observed pharmacy study sites during the implementation of MR services. Both qualitative and quantitative data were collected across exploration, preparation, testing, and operational phases. Implementation outcomes evaluated include phases, reach, fidelity, acceptability, as well as implementation barriers and strategies. MR intervention outcomes included service characteristics and the number and type of drug-related problems and interventions offered.

Results

17 community pharmacists were invited to pilot the MR service blueprint for six months in their setting. Of this, 78.5% (n = 11) of the pharmacies reached the testing phase, and 36% (n = 4) reached the implementation phase. Fifty-four patients were in the study, giving an implementation reach of 70%. The majority of surveyed patients expressed satisfaction with the service. The total DRP identified was 133, and 64 interventions were provided by the pharmacists. Facilitation strategies such as “Engage stakeholders by creating ownership of the change” and “Equip stakeholders with training” are needed to overcome the barriers.

Conclusion

This study marked the beginning of successful MR service implementation at Malaysian community pharmacies. Future studies with multi-level partnered strategies are required to reach full implementation and sustainability.
SARS-CoV-2 Delta variant remains viable in environmental biofilms found in meat packaging plants
Authors: Featherstone Austin B. , Mathijssen Arnold J. T. M. , Brown Amanda , Chitlapilly Dass Sapna
Published: June 2024

To determine why SARS-CoV-2 appears to thrive specifically well in meat packaging plants, we used SARS-CoV-2 Delta variant and meat packaging plant drain samples to develop mixed-species biofilms on materials commonly found within meat packaging plants (stainless steel (SS), PVC, and ceramic tile). Our data provides evidence that SARS-CoV-2 Delta variant remained viable on all the surfaces tested with and without an environmental biofilm after the virus was inoculated with the biofilm for 5 days at 7°C. We observed that SARS-CoV-2 Delta variant was able to remain infectious with each of the environmental biofilms by conducting plaque assay and qPCR experiments, however, we detected a significant reduction in viability post-exposure to Plant B biofilm on SS, PVC, and on ceramic tile chips, and to Plant C biofilm on SS and PVC chips. The numbers of viable SARS-CoV-2 Delta viral particles was 1.81–4.57-fold high than the viral inoculum incubated with the Plant B and Plant C environmental biofilm on SS, and PVC chips. We did not detect a significant difference in viability when SARS-CoV-2 Delta variant was incubated with the biofilm obtained from Plant A on any of the materials tested and SARS-CoV-2 Delta variant had higher plaque numbers when inoculated with Plant C biofilm on tile chips, with a 2.75-fold difference compared to SARS-CoV-2 Delta variant on tile chips by itself. In addition, we detected an increase in the biofilm biovolume in response to SARS-CoV-2 Delta variant which is also a concern for food safety due to the potential for foodborne pathogens to respond likewise when they come into contact with the virus. These results indicate a complex virus-environmental biofilm interaction which correlates to the different bacteria found in each biofilm. Our results also indicate that there is the potential for biofilms to protect SARS-CoV-2 from disinfecting agents and remaining prevalent in meat packaging plants.
Similarity-driven motion-resolved reconstruction for ferumoxytol-enhanced whole-heart MRI in congenital heart disease
Authors: Romanin Ludovica , Milani Bastien , Roy Christopher W. , Yerly Jérôme , Bustin Aurélien , Si-mohamed Salim , Prsa Milan , Rutz Tobias , Tenisch Estelle , Schwitter Juerg , Stuber Matthias , Piccini Davide
Published: June 2024

A similarity-driven multi-dimensional binning algorithm (SIMBA) reconstruction of free-running cardiac magnetic resonance imaging data was previously proposed. While very efficient and fast, the original SIMBA focused only on the reconstruction of a single motion-consistent cluster, discarding the remaining data acquired. However, the redundant data clustered by similarity may be exploited to further improve image quality. In this work, we propose a novel compressed sensing (CS) reconstruction that performs an effective regularization over the clustering dimension, thanks to the integration of inter-cluster motion compensation (XD-MC-SIMBA). This reconstruction was applied to free-running ferumoxytol-enhanced datasets from 24 patients with congenital heart disease, and compared to the original SIMBA, the same XD-MC-SIMBA reconstruction but without motion compensation (XD-SIMBA), and a 5D motion-resolved CS reconstruction using the free-running framework (FRF). The resulting images were compared in terms of lung-liver and blood-myocardium sharpness, blood-myocardium contrast ratio, and visible length and sharpness of the coronary arteries. Moreover, an automated image quality score (IQS) was assigned using a pretrained deep neural network. The lung-liver sharpness and blood-myocardium sharpness were significantly higher in XD-MC-SIMBA and FRF. Consistent with these findings, the IQS analysis revealed that image quality for XD-MC-SIMBA was improved in 18 of 24 cases, compared to SIMBA. We successfully tested the hypothesis that multiple motion-consistent SIMBA clusters can be exploited to improve the quality of ferumoxytol-enhanced cardiac MRI when inter-cluster motion-compensation is integrated as part of a CS reconstruction.
Can digital economy foster synergistic increases in green innovation and corporate value? Evidence from China
Authors: Song Guomin , Wang Fengyan , Dong Feng
Published: June 2024

The rapid evolution of the digital economy has significantly accelerated progress towards achieving green and sustainable processes, particularly in the field of green production. While existing research has delved into the effects of the digital economy on Green Innovation (GI) and the consequences of digital transformation on Corporate Value (CV), there remains a notable gap in the literature regarding the potential for synergistic enhancements in firms’ GI&CV through the ongoing digital revolution. This study utilizes an evolutionary game model and employs system dynamics methods to simulate the dynamic evolution trajectory of the influence of the digital economy on the synergy between GI&CV. Subsequently, it empirically assesses the interconnected synergies between GI&CV using a dataset comprising information from Chinese listed firms spanning from 2011 to 2020, examining the impact of the digital economy on these synergies. Moreover, the study delves into the analysis of the transmission mechanism and conducts an extended investigation to further explore this phenomenon. The findings of this paper including: (1) The digital economy acts as a driving force behind the synergistic enhancement of firm GI&CV. Moreover, this effect is further augmented by governmental environmental regulation and green subsidy policies. (2) Drawing upon the information asymmetry theory and the resource-based theory, the regional marketization level and firms’ digital transformation play intermediary roles. (3) The heterogeneity test indicate that firms situated in eastern regions and those classified as non-heavily polluted benefitted to a greater extent. This study sheds light on the incentive implications of digital economy for the synergistic upgrading of GI&CV, thereby extending the breadth of study on the consequences of digital economy. Moreover, it offers actionable suggestions for enterprises to leverage digital economy development towards achieving a synergistic improvement of GI&CV.
Mentoring practices that predict doctoral student outcomes in a biological sciences cohort
Authors: Debray Reena , Dewald-Wang Emily A. , Ennis Katherine K.
Published: June 2024

Despite the importance of a diversity of backgrounds and perspectives in biological research, women, racial and ethnic minorities, and students from non-traditional academic backgrounds remain underrepresented in the composition of university faculty. Through a study on doctoral students at a research-intensive university, we pinpoint advising from faculty as a critical component of graduate student experiences and productivity. Graduate students from minority backgrounds reported lower levels of support from their advisors and research groups. However, working with an advisor from a similar demographic background substantially improved productivity and well-being of these students. Several other aspects of mentoring practices positively predicted student success and belonging, including frequent one-on-one meetings, empathetic and constructive feedback, and relationships with other peer or faculty mentors. Our study highlights the need to renovate graduate education with a focus on retention–not just recruitment–to best prepare students for success in scientific careers.
Milk levels of transforming growth factor beta 1 identify mothers with low milk supply
Authors: Sullivan Rhea , Confair Alexandra , Hicks Steven D.
Published: June 2024

Human milk is optimal for infant nutrition. However, many mothers cease breastfeeding because of low milk supply (LMS). It is difficult to identify mothers at risk for LMS because its biologic underpinnings are not fully understood. Previously, we demonstrated that milk micro-ribonucleic acids (miRNAs) may be related to LMS. Transforming growth factor beta (TGFβ) also plays an important role in mammary involution and may contribute to LMS. We performed a longitudinal cohort study of 139 breastfeeding mothers to test the hypothesis that milk levels of TGFβ would identify mothers with LMS. We explored whether TGFβ impacts the expression of LMS-related miRNAs in cultured human mammary epithelial cells (HMECs). LMS was defined by maternal report of inadequate milk production, and confirmed by age of formula introduction and infant weight trajectory. Levels of TGF-β1 and TGF-β2 were measured one month after delivery. There was a significant relationship between levels of TGF-β1 and LMS (X2 = 8.92, p = 0.003) on logistic regression analysis, while controlling for lactation stage (X2 = 1.28, p = 0.25), maternal pre-pregnancy body mass index (X2 = 0.038, p = 0.84), and previous breastfeeding experience (X2 = 7.43, p = 0.006). The model accounted for 16.8% of variance in the data (p = 0.005) and correctly predicted LMS for 84.6% of mothers (22/26; AUC = 0.72). Interactions between TGF-β1 and miR-22-3p displayed significant effect on LMS status (Z = 2.67, p = 0.008). Further, incubation of HMECs with TGF-β1 significantly reduced mammary cell number (t = -4.23, p = 0.003) and increased levels of miR-22-3p (t = 3.861, p = 0.008). Interactions between TGF-β1 and miR-22-3p may impact mammary function and milk levels of TGF-β1 could have clinical utility for identifying mothers with LMS. Such information could be used to provide early, targeted lactation support.
Trove: Still a buried treasure
Authors: Green Kerry , Green Candice
Published: June 2024

The process of digitization has proven to be a boon for researchers, and especially for historians, because producing a digitized record of a thing allows researchers anywhere in the world to have access to artefacts. Digitization is especially important for mass communication researchers studying issues surrounding news. Digitization of news publications enables researchers to conduct word, phrase or other thematic searches using appropriate software. But where content has not been digitized, researchers must undertake cumbersome searches by physically reading through the original documents or some analogue record, like microfiche, and then they are limited by the assiduity of themselves, their teams and by the degradation of the originals as they age. Researchers in Australia are considerably assisted by the existence of the Trove database, which has digitized the content of Australian newspapers up to the end of 1954. The National Library of Australia considers Australian copyright law, which says content must be at least 70 years old, limits what may be digitized. Researchers who want to look at more recent news content must do so via state libraries’ microfiche records, limiting access. To make access equitable and democratic, Trove should digitize newspaper content into the twenty-first century.
Argumentazioaren teoriaren historia
Authors: Huizi Pello
Published: June 2024

Lan honen helburua, historian zehar garatu diren argumentazioari buruzko teoria nagusiak —edo horietako batzuk, hobeto esanda— aurkeztea da. Antzinako Greziatik abiatuko gara: sofistak eta, batez ere, Aristoteles hartuko ditugu gogoan. Gero, Erromazaharrera joango gara: Zizeronen eta Kintilianoren lanen oinarriak azalduko ditugu, eta baita egile ezagunik ez duen Rhetorica ad Herenniumenak ere. Hurrengo atala argumentazio-teorien gainbehera luzeari eskainiko diogu. Ondoren, Stephen Toulminek eta Chaïm Perelmanek 1958an argumentazioari buruz egindako ikerketak, eta horiek eragin zuten berpizkundea, aipatuko ditugu. Eta, azken atalean, egile horien lan aitzindariari jarraituz, azken hamarkadetan egin diren ekarpenik garrantzitsuenak aztertuko ditugu.
Emozio positiboak: alde argiak eta alde ilunak
Authors: Huizi Pello
Published: June 2024

Emozio positiboen alde argi eta alde ilunak aztertzea da lan honen helburua. Hori dela eta, aurrena emozio positiboen eta emozio negatiboen arteko ezberdintasunak aurkezten ditut, baita emozio positiboei buruzko ikerketari eskaini izan zaion lekua ere psikologiaren historian. Emozio positiboen eta negatiboen arteko aldeak direla eta, “balentzia” kontzeptuaren garrantziaz eta esanahiaz hitz egiten dut. Emozio positiboen alde argiei dagokienez, ikertzaileek arreta handiz aztertutako hiru arlo hartzen ditut kontuan: emozio positiboen eta osasunaren (eta longebitatearen) arteko lotura, emozio positiboaren eta kognizioaren artekoa eta emozio positiboaren eta pertsona arteko harremanen arteko lotura. Emozio positiboen alde ilunei dagokienez, ikertzaileek aurkitu dituzten emozio positibo batzuen, gehien aztertu direnen, ondorio negatiboen berri ematen dut. Gruber eta Purcellek (2015), emozio positiboek izan ditzaketen emaitza txar motak laburbildu nahian, proposatzen dituzten sei sail edo multzo nagusien aurkezpen laburra eginez bukatzen dut artikulua.
Bilingual minds
Authors: Huizi Pello
Published: June 2024

Oraintsu arte, elebiduna izatearekin lotuta dauden gai eta arazoez aritu diren ikerketek hiru arlo nagusi hauek izan dituzte aztergai: elebitasuna eta adimena, bigarren hizkuntzaren eskurapena, eta elebitasunaren ikuspuntu psikolinguistikoa eta ikuspuntu soziolinguistikoa. Elebitasunaren eta adimenaren arteko harremanari dagokionez, galdera eta kezka zen ea elebitasuna kaltegarria den adimenaren garapenarentzat. Bigarren hizkuntzaren jabe egitea dela eta, galdera nagusiak bi ziren: zein den hor ama hizkuntzaren rola eta zein faktorek dakarten batzuek arrakasta izatea eta beste batzuek ez. Azkenik, aipatu bi ikuspuntuei dagokienez, elebitasuna nola kontzeptualizatu nahi zen zen kontua, fenomeno psikolinguistiko gisa ala fenomeno soziolinguistiko gisa. Lehenengo kasuan, elebidunak bi hizkuntzetan zuen gaitasun erlatiboaz galdetzen zen; bigarrenean, aldiz, gizabanako elebiduna zein hizkuntza komunitatekoa zen.
Manifestações do Mundo Vuca no contexto pandêmico e as consequências físicas e mentais em teletrabalhadores do setor privado
Authors: Wilhelm Berwanger Jane Lúcia , Vasconcelos Filho Oton Albuquerque de , Camelo Lahys de Lima
Published: June 2024

O presente artigo objetiva analisar de que maneira o adoecimento de teletrabalhadores do setor privado durante a pandemia de Covid-19 se relaciona com aspectos característicos do Mundo VUCA. A partir de discussões que apontam a volatilidade, a incerteza, a complexidade e a ambiguidade como características da pós-modernidade, procura lançar um olhar crítico sobre a expansão do teletrabalho enquanto modalidade laboral, em especial durante o período pandêmico. O conteúdo dados coletados, de natureza bibliográfica, foram analisados qualitativamente e sistematizados em torno de duas categorias centrais às reflexões propostas: aspectos econômicos, sendo aqueles relacionados aos efeitos diretos e indiretos da pandemia na economia global; e aspectos socioculturais e pessoais, vinculada aos efeitos não- econômicos, mas que aprofundaram as características do Mundo VUCA no contexto do teletrabalho. Os resultados alcançados apontam para a necessidade de se pensar estratégias de cuidado físico e mental dos teletrabalhadores e situam a importância dos profissionais do Direito na garantia dos direitos da categoria, bem como na minimização dos riscos de adoecimento.
Polymer composites for medical applications as artificial bones
Authors: Filip Damian , Bulanda Katarzyna
Published: June 2024

Polymer composites based on epoxy resin (EP) were developed from which anatomical models of artificial cortical bone tissue were obtained. The cancellous was polyurethane foam. To obtain appropriate mechanical properties, the EP was filled with CaCO3 (50, 60, 70 wt%) and a hybrid filler in the form of a mixture of silica and perlite (3/3, 5/5, 7/7 wt%/wt%). Samples for mechanical testing were obtained by vacuum casting in silicone molds. The influence of the type and amount of filler on the mechanical properties of the composite was demonstrated. CaCO3 had a particularly beneficial effect on hardness, compressive stress, and Young's modulus. The obtained anatomical bone model did not differ from natural bone in terms of structure and properties. This type of implants can be used in orthopedics and veterinary medicine.
Atmospheric plasma treatment of rubber and its effect on surface characteristics
Authors: Ďurišová Silvia , Pajtášová Mariana , Ondrušová Darina , Janík Róbert , Mičicová Zuzana , Dubec Andrej , Pagáčová Jana , Šulcová Jana , Božeková Slavomíra , Vavro Jan , Klepka Tomasz
Published: June 2024

The changes of rubber blend surface induced by atmospheric plasma at several conditions were studied via FTIR, SEM, contact angle and adhesion measurement. After plasma, the presence of OH, COO- bands of higher intensity was observed, whilst methylene groups reduced. A several formations of weaker agglomeration and cleaning of the surface was recognized. Also an intense decline of contact angles was observed. The plasma induced significantly greater changes at the 0.5 mm position, whereas emission times of 10 s and       30 s did not significantly affect the modifications of the investigated surface.
Study of Sensitivity Index for Landslide Disaster in Gunungpati Sub-district, Semarang City
Authors: Pambayun Mahendra Ken , Helmi Muhammad , Muhammad Fuad
Published: June 2024

Sensitivity is one of the parameters of the vulnerability in a disaster. Gunungpati Sub-district is one of the sub-districts that had a high-intensity landslide in Semarang city. Assessment of the sensitivity index to disasters is necessary to reduce vulnerabilities and to become a consideration for policy-taking factors in the emergence of disasters. The sensitivity index uses the population density, building density, sex ratio, dependency ratio, poverty rate, and education level. The method used is a weighted scoring method for each sensitivity variable. The sensitivity index of the Gunungpati Sub-district on landslide ranges from 2.6 - 2.8. Sensitivity levels of the Gunungpati Sub-district are classified into three classes there are little sensitive, moderately sensitive, and sensitive classes. Five villages have high sensitivity values. Special attention from the government is needed to increase the capacity of the population in terms of social and economic aspects to reduce the high sensitivity value in the area. Mitigation that can be done by the government related to the sensitivity of this area can be through policies such as capital assistance and training for vulnerable groups, equalization of employment, making policies, and strict control of development permits in areas at risk of landslides.
Zeolites Effects in Physical Characteristics of Low-Density Polyethylene (LDPE) and Polypropylene (PP) Pyrolysis into Liquid Fuel
Authors: Mayora Elsa Meilia , Arifin Arifin , Nugraheni Putranty Widha
Published: June 2024

The decline in the quality of waste management has generally started to occur since the prolonged economic crisis in Indonesia. Plastic waste includes inorganic waste, which is currently widely used by industry and households. Therefore, it is necessary to have an alternative recycling process, like converting plastic waste into liquid fuel. The research objective is to utilize LDPE plastic waste (Low-Density Polyethylene) and PP (Polypropylene)in liquid fuelutilizing pyrolysisto determine the effect of using a zeolite catalyst by comparing the results of the pyrolysis process. The investigation took place at the Wonosari landfill in Singkawang, where parameters such as density, viscosity, and color were examined. The pyrolysis results underwent consistency testing through the Mann-Whitney test. According to the study findings, the average physical parameter values for viscosity and density of LDPE pyrolysis liquid fuel were 0.302 cP, LDPE+catalyst was 0.114 cP, with densities of 767 kg/m3 and 737 kg/m3. For PP, the average viscosity was 2.812 cP, and PP+catalyst was 0.248 cP, with densities of 774 kg/m3 and 735 kg/m3. Samples of PP and LDPE with catalysts exhibited lower density values compared to those without catalysts.
Bonding over bashing: Discussing LGBTI topics in far-right alternative news media comments sections
Authors: Verhoeven Emma
Published: June 2024

This study investigates virtual community-building practices and discriminatory views in PAL NWS, a Dutch-speaking Belgian far-right alternative news medium, by examining discussions in the comments sections. Thematic analysis was applied to a total of 1,127 comments by 343 users in response to 50 articles about LGBTI topics. The findings show that far-right alternative news sites can function as virtual communities that facilitate polarization. The comments exhibited a high level of hostility towards LGBTI individuals, particularly toward transgender people and public displays of LGBTI inclusion. Furthermore, Muslims were homogeneously perceived as homophobes, and LGBTI topics were understood as (woke) ideological suppression by a dogmatic minority. The results of this study have implications for understanding the dynamics of comments sections on alternative media and the potential for far-right news platforms to facilitate the spread of intolerance.
(De)Gendering (English-Spanish) Translation of Legal Texts
Authors: Vázquez y del Árbol Esther
Published: June 2024

Within Western culture, gender is frequently interpreted in terms of binarism (male versus female), derived from biological sex at birth. Nevertheless, there is an accelerating percentage of non-binary and transgender people, who are not related to binary nomenclature, and they also need to resort to legal documentation and their renderings into other languages. This fact becomes a troublesome issue that must be nowadays solved, especially when translating into Spanish, a grammatical gender language, from English, a non-grammatical gender language. In this paper we will first select a corpus of eight British legal documents representing highly demanded translation briefs. We will then search for 15 problematic lexical items, searching for their lexicographic definitions and translations, and we will later resort to their most feasible translations into the Spanish language, considering both gendered translations and genderless ones. Our research shows how the Spanish language has its own translation techniques, especially paraphrasing, to be able to provide the English-Spanish target readership with binary legal terms, and especially with non-binary ones.
Análise empírica sobre a sistemática ritualística erudita e popular do Tribunal do Júri sob o pálio dos direitos humanos garantidos constitucionalmente
Authors: Heinze Eric , SILVA R. A.
Published: June 2024

This article constitutes the second material made from the free and empirical ethnographic analysis of several sessions of the jury, specifically regarding the idiosyncratic performance of its main characters: Judge, prosecutor, defender and Council of Judgment. It does not lend itself to the definitiveness of the selected theme, neither does it build undisputed thesis. It is based on eyewitness observation concept of jurisdictional plenary and it is designed to cast doubt on the unfailing concreteness of the jury as maintainer instrument of constitutional guarantees of a Law-based Democratic State to finally stimulate an academic dialogue on Human Rights.
The Consolidation of Newly Learned Movements Depends upon the Somatosensory Cortex in Humans
Authors: Ebrahimi Shahryar , van der Voort Bram , Ostry David J.
Published: June 2024

Studies using magnetic brain stimulation indicate the involvement of somatosensory regions in the acquisition and retention of newly learned movements. Recent work found an impairment in motor memory when retention was tested shortly after the application of continuous theta-burst stimulation (cTBS) to the primary somatosensory cortex, compared with stimulation of the primary motor cortex or a control zone. This finding that the somatosensory cortex is involved in motor memory retention whereas the motor cortex is not, if confirmed, could alter our understanding of human motor learning. It would indicate that plasticity in sensory systems underlies newly learned movements, which is different than the commonly held view that adaptation learning involves updates to a motor controller. Here we test this idea. Participants were trained in a visuomotor adaptation task, with visual feedback gradually shifted. Following adaptation, cTBS was applied either to M1, S1, or an occipital cortex control area. Participants were tested for retention 24 h later. It was observed that S1 stimulation led to reduced retention of prior learning, compared with stimulation of M1 or the control area (with no significant difference between M1 and control). In a further control, cTBS was applied to S1 following training with unrotated feedback, in which no learning occurred. This had no effect on movement in the retention test indicating the effects of S1 stimulation on movement are learning specific. The findings are consistent with the S1 participation in the encoding of learning-related changes to movements and in the retention of human motor memory.
Análisis de los principales indicadores socioeconómicos del sector agropecuario ecuatoriano (2000-2022)
Authors: Pino Peralta Sergio , Ortega Álvarez Kevin
Published: June 2024

The agricultural sector in Ecuador, a key player in the country’s economic system, is currently facing important challenges that threaten the sustainability of production. Consequently, the objective of this research was to analyze the main socioeconomic indicators of the Equatorian agricultural sector during the 2000-2022 period. Using a descriptive methodology with quantitative and analytical-synthetic methods, information was sourced from BCE and INEC. Results show that agricultural activities contribute 7.92% to Ecuador’s GDP, generate 35% of foreign exchange earnings, and yield 94.84% of the food consumed by the population. However, agricultural production is concentrated on a few primary goods. In addition, the agricultural frontier has been reduced in recent years, there is evidence of a process of disinvestment by the State in the agricultural sector, and the agricultural GDP growth rate shows a downward trend. Therefore, current administrations in Ecuador have not attempted to change to a model that would honor the efforts of the rural population.
GEOCHEMISTRY AND MINERALOGY OF RARE-EARTH ELEMENTS IN FERRUGINOUS DEPOSITS AND BOTTOM SEDIMENTS OF THE LAPTEV SEA
Authors: КОЛЕСНИК О.Н. , КОЛЕСНИК А.Н. , АСТАХОВ А.С.
Published: June 2024

Проанализированы геохимические и минералогические аспекты распределения редкоземельных элементов (РЗЭ) в железистых образованиях (ЖО) и донных осадках юго-восточной части моря Лаптевых. Среди ЖО преобладают биоморфозы по трубкам полихет. Общее содержание и распределение РЗЭ в ЖО складывается из соотношения рудного и нерудного вещества. Рудное вещество представлено в основном гидроксидами железа (лимонит). Оно сформировалось в ходе субокислительного диагенеза, усиленного процессами биотурбации, и определяет в ЖО некоторый избыток средних РЗЭ и дефицит церия (Ceан - 0.94). Нерудное вещество поступает в ЖО из терригенных осадков и имеет (алюмо)силикатный состав. Оно определяет в ЖО содержание скандия и является источником зерен минералов РЗЭ, среди которых преобладает монацит-(Ce). Для осадков характерно общее подобие составу РЗЭ в сланцах и во взвеси р. Лена, впадающей в море Лаптевых, при небольшом избытке легких и средних РЗЭ и величине цериевой аномалии, практически равной единице (Ceан - 1.06). В осадках минералы РЗЭ тяготеют к фракциям мельче 63 мкм. Высокое содержание в осадках органического вещества (Сорг - до 2.15 %), имеющего преимущественно терригенный генезис (ОВтер - до 85 %), объясняет дефицит кислорода и общее вялое протекание процессов диагенетического минералообразования со слабым накоплением в ЖО микроэлементов, включая РЗЭ. Суммарное содержание РЗЭ в ЖО ниже, чем в осадках, и составляет в среднем 173 против 206 г/т.

The geochemical and mineralogical aspects of the distribution of rare-earth elements (REE) in ferruginous deposits (FD) and bottom sediments of the southeastern Laptev Sea are analyzed. The FD are dominated by biomorphs developed after polychaete tubes. The REE patterns depend on the proportion of ore and non-ore substances. The ore substance is represented mainly by iron hydroxides (limonite). It is a product of suboxic diagenesis enhanced by bioturbation and determines the slight enrichment of FD in MREE and cerium deficiency (Cean = 0.94). The non-ore substance comes from terrigenous sediments and has an (alumino)silicate composition. It controls the scandium content and is the source of REE mineral grains, among which monazite-(Ce) prevails. The sediments demonstrate a common similarity in REE patterns to shales and suspended material transported to the Laptev Sea by the Lena River, with elevated LREE and MREE contents and the value of Ce anomaly almost equal to unity (Cean = 1.06). In the sediments, REE minerals occur mostly in the silt fraction (<63 μm in size). The high content of organic matter (Corg of up to 2.15%) of predominantly terrigenous origin (OMter of up to 85%) in the sediments explains the oxygen deficiency and weak diagenetic mineral formation with low accumulation of trace elements, including REE, in the FD. The total REE content in the FD is lower than that in the sediments (on average, 173 ppm against 206 ppm).
SNP analysis of Ukrainian maize inbreds with alternative state of molecular carotenogenesis marker crtRB1-3’TE
Authors: Denysiuk K. V. , Satarova T. M. , Semenova V. V. , Cherchel V. Yu. , Soudek P. , Dziubets’kiy B. V.
Published: June 2024

Aim. SNP analysis and estimation of genetic relations in maize inbreds with the alternative state of β-carotene hy-
droxylase 1 gene (crtRB1) by the molecular marker crtRB1-3ʹTE. Methods. SNP analysis, statistical methods. BDI-
III panel with 384 SNP markers was used for comparative research of 35 maize inbreds developed and adopted in
the northern Steppe of Ukraine. Results. SNP analysis of investigated inbred set showed that the part of dimorphic
markers was 98.2 %, the average minor allele frequency (MAF) was 0.3040, the average polymorphism information
content (PIC) was 0.3064, and the average shift of genetic diversity of markers was 0.3898. There was no significant
difference between genetic SNP distances within both groups of inbreds with favourable/unfavourable alleles and
between these groups by crtRB1-3ʹTE. The SNP distances were used to build a dendrogram of genetic relations be-
tween maize inbreds with an alternative state of the crtRB1-3ʹTE marker. Conclusions. The relationship between the
allelic state of the β-carotene hydroxylase 1 gene and single nucleotide polymorphism markers for maize inbreds is
presented. The alleles of SNP markers BDI-III-130A, BDI-III-15A, BDI-III-60C, BDI-III-61C, BDI-III-116G, BDI-
III-128A, and BDI-III-129A were found to be most frequent in the inbreds, which are carriers of the favourable allele
of 543 bp of crtRB1 gene by the crtRB1-3ʹTE marker. The random distribution of alleles of this gene among maize
inbreds developed in the northern Steppe of Ukraine was demonstrated.
La globalización de capital, las crisis del siglo xxi, y el rezago de américa latina: ¿qué sigue?
Authors: Levy Orlik Noemi Ornah
Published: June 2024

El modelo económico dominante sustentando en la globalización e internacional del capital se ha vuelto disfuncional y se encuentra en un proceso reorganización.
En este trabajo se revisan los conceptos básicos de la era Neoliberal y las claves de la organización económica que son la complejización financiera y las cadenas globales de producción. Este análisis se hará en el contexto Latinoamericano mostrando que la especialización productiva asignada a la región mantuvo el atraso tecnológico y la exclusión de las clases populares, lo cual, está generando una serie de conflictos sociales y se buscan nuevas formas de producción del capital.
Formation of Cognitive-Technological Competence as a Mechanism of Realisation of Rational Component in Training Undergraduate Students
Authors: Ignatenko Natalia , Savenco Victor , Kryskov Andrii , Habrusieva Nataliia , Tetiana Remekh , Lemiszka Diana
Published: June 2024

Aim. The purpose is to consider the theoretical and methodological foundations of the formation of cognitive-technological competence as a mechanism for implementing the rational component in the training of a history teacher, the essence of the concepts "rationality in education", "rationality in science", "cognitive-technological competence" is revealed”.
Methods. The theoretical method of forming cognitive-technological competence in the process of studying the history of Europe and America has been substantiated, developed and tested. The model includes the unity of methodological, content-technological and evaluation-resultative components.
Results. The analysis shows that focusing attention on the leading role of the teacher in the formation of the students’ mental activity requires the student to understand the logic and mechanisms of human mental development.
Conclusion. At the same time, a number of unresolved issues in the process of working with students were highlighted, in particular: the need for a broad discussion of the advantages and disadvantages of distance learning in the implementation of the rational component of undergraduate students, the development of students' responsibility for learning, training on the development of cognitive and technological competence of students of the master's degree in specialty 014.03 "Secondary education ( history)" in the conditions of a pandemic.
Voegelin, Eric. Política, historia, conciencia (edición de Charles R. Embry y Glenn Hughes; traducción a cargo de Francisco Ortega Olmo), Guillermo Escolar Editor, Madrid, 2023, 397 pp.
Authors: Manrique-Mattos Diego-Alejandro
Published: June 2024

Book Review
Expression and Purification of Active Human 17β-Hydroxysteroid Dehydrogenase Type 1 from Escherichia coli
Authors: Bekić Sofija S. , Plavša Jovana J. , Pavšič Miha , Lenarčič Brigita , Petri Edward T. , Ćelić Andjelka S.
Published: June 2024

Breast cancer cell growth is often dependent on the presence of steroidal hormones. The 17β-hydroxysteroid dehydrogenase type 1 isoform (17βHSD1) catalyzes NADPH-dependent conversion of estrone to estradiol, a more potent estrogen, and represents potential drug target for breast cancer treatment. To provide active enzyme for inhibitor screening, 17βHSD1 is usually expressed in insect or mammalian cells, or isolated from human placenta. In the present study we describe a simple protocol for expression and purification of active human 17βHSD1 from Escherichia coli BL21(DE3) cells. Soluble human 17βHSD1 was expressed using a pET28a(+)-based plasmid, which encodes a hexahistidine tag fused to the N-terminus of the protein, and purified by nickel affinity chromatography. The enzyme activity of purified 17βHSD1 was verified by three methods: thin-layer chromatography, an alkali assay and a spectroscopic assay. These non-radioactive enzyme assays require only standard laboratory equipment, and can be used for screening compounds that modulate 17βHSD1 activity.
Synthesis, Crystal Structures and Urease Inhibition of Copper(II) and Zinc(II) Complexes Derived from N,N’-Bis(4-bromosalicylidene)-1,3-propanediamine
Authors: Chen Hai-Ying , Lu Rundong , Lei Jinkai , Liu Jiacheng , Liu Chi , Chen Liuxiu , Chen Wu
Published: June 2024

A new tetranuclear copper(II) complex [Cu4L2(N3)2(CH3OH)2](NO3)2·4CH3OH (1) and a new trinuclear zinc(II) complex [Zn3L2(CH3COO)2] (2) have been prepared from the bis-Schiff base N,N’-bis(4-bromosalicylidene)-1,3-propanediamine (H2L) with copper nitrate and zinc acetate, respectively, in the presence of sodium azide. The complexes were characterized by elemental analysis, IR and UV-Vis spectroscopy. Molecular structures of both complexes were confirmed by single crystal X-ray determination. The Cu(II) atoms in complex 1 are bridged by phenolate oxygen atoms and end-on azide ligands. The Zn(II) atoms in complex 2 are bridged by phenolate oxygen atoms and acetate ligands. The Cu(II) atoms in complex 1 are in square planar and square pyramidal coordination. The Zn(II) atoms in complex 2 are in square pyramidal and octahedral coordination. The Schiff base ligand coordinates to the metal atoms through two phenolate O and two imino N atoms. The biological assay reveals that the copper(II) complex has effective urease inhibition.
Journey to Quality 6.0: Evolution of quality management across industrial revolutions
Authors: Tereza Smajdorova
Published: June 2024

This article explores the development of industrial revolutions and their relationship to the evolution of quality management from the first to the fifth revolution. The analysis covers significant changes in manufacturing processes, technologies, and business models that shaped the concept of quality in industry. Special emphasis is placed on the transition from manual labor to automation, the development of industrial standards, and the increasing role of quality in corporate leadership. Furthermore, the article introduces considerations about the potential form of the sixth industrial revolution, highlighting the impacts of artificial intelligence, the Internet of Things, and digitization on the future of industry. A focal point of interest is the visualization of “Quality 6.0,” representing the next level of quality management in light of emerging technologies and industrial trends. This article offers a perspective on how quality management could respond to the anticipated sixth industrial revolution and what innovative quality might look like in the digital era.
IMPACT OF SANCTIONS ON EMPLOYMENT AND UNEMPLOYMENT IN RUSSIAN REGIONS: ANALYSIS OF DYNAMICS AND MAIN TRENDS
Authors: Кондратьев Р.А.
Published: June 2024

Актуальность исследуемой темы обусловлена нарастающим воздействием экономических санкций на социально-экономическое развитие страны. В условиях глобализации экономические санкции становятся инструментом политического и  экономического давления, что приводит к значительным изменениям в экономике страны, влияя на уровень занятости и безработицы в различных регионах. Различная степень уязвимости регионов перед лицом санкционной политики требует детального анализа, что делает тему крайне важной для исследования. Оценка влияния санкций на занятость и безработицу позволит выработать рекомендации по смягчению негативных эффектов для социально-экономического развития регионов и страны в целом.

The relevance of the studied topic is due to the growing impact of economic sanctions on the socio-economic development of the country. In the conditions of globalization, economic sanctions become an instrument of political and economic pressure, which leads to significant changes in the country’s economy, affecting the level of employment and unemployment in different regions. The different degree of vulnerability of regions to the sanctions policy requires a detailed analysis, which makes the topic extremely important for the research. Assessing the impact of sanctions on employment and unemployment will make it possible to develop recommendations to mitigate the negative effects on the socio-economic development of regions and the country as a whole.
EURASIAN INTEGRATION: TRANSPORT ASPECT
Authors: Дроздова М.А.
Published: June 2024

В статье рассматривается транспортный аспект интеграционных процессов в Евразийском регионе, основные проблемы правового регулирования указанной сферы. Автором обосновывается необходимость корректировки существующего подхода к формированию актуальной модели международно-правового регулирования евразийской транспортной интеграции как важной составляющей обеспечения конкурентоспособности России как на региональном, так и на глобальном уровне. Для полноценной реализации евразийского транзитного потенциала, а также для обеспечения технологического суверенитета России необходима гармонизация законодательства стран-партнеров в сфере регламентации применения технологий Индустрии 4.0 в транспортно-логистической отрасли.

The article addresses the integration processes’ transport aspect in the Eurasian region, reviews the main issues of transport and logistics legal regulation of this sphere. The researcher substantiates the need to adjust the existing approach to the development of an actual model of international legal regulation of Eurasian transport integration, since it is an important pillar of ensuring Russia’s competitiveness both at regional and global levels. It is necessary to harmonize the legislation of EAEU and China about use of Industry 4.0 technologies in transport and logistics. It would provide for realization of the Eurasian transit potential, as well as ensuring the Russia’s technological sovereignty.
¿Teoría o práctica? Sobre las definiciones que rodean a la investigación - creación
Authors: Brianza Alejandro
Published: June 2024

Atendiendo a la problemática actual de repensar la realidad del contexto académico en relación a la investigación en el terreno del arte, este artículo plantea un recorrido por las distintas definiciones que fueron moldeando lo que hoy conocemos como investigación - creación, atendiendo tanto a su perspectiva epistemológica como a sus propuestas metodológicas.