bluuebunny/crossref_metadata_2025 huggingface dataset:
Maternal relationships and motivation in gifted children
Authors: ARSLAN Kübra , YURTAL Filiz
Published: February 2022

This study primarily investigates gifted children's and their mothers' acceptance-rejection and control perceptions and children's achievement motivation. The study was carried out with 5th and 6th year students attending Science and Art Centers in two cities in Turkey, and their mothers. The sample of this research is 226 students (103 girls and 126 boys) and 179 mothers. As data collection tools, Turkish Parent Parental Acceptance-Rejection Questionnaire/Control: Child (Short Form), Child Parental Acceptance-Rejection Questionnaire/Control: Mother (Short Form), and Scale of Motivation in Education were used. The results of the study showed that children and mothers perceived high level acceptance, low level rejection and mid-level control in their mother-child relationships. A significant difference was observed between mothers' and children's perceived parental acceptance-rejection and control. It was also seen that children's identified external motivation and intrinsic motivation levels were high and amotivation and introjected external motivation levels were low.
Hidden association of knee-related disability with physical activities among community-dwelling older male Saudi Arabians with knee osteoarthritis
Authors: Ateef Mahamed
Published: February 2022

Introduction: The impact of knee osteoarthritis (OA) on physical activities of daily life was studied extensively among the elderly across the globe but not well understood in the Saudi Arabian populace with cultural consideration. This paper assessed the association between knee flexion range of motion (ROM) and ritual physical activities among elderly males due to knee OA.Methods: A cross-sectional study with a sample of 139 males aged 56–74 years diagnosed with knee OA recruited at prayer places. The subjective evaluation was carried using a disease-specific Arabic knee physical functional questionnaire Knee injury and OA Outcome Score-Physical Function Short form (KOOS-PS), and the anthropometric measure of knee flexion ROM was objectively measured by a manual goniometer.Results: The mean and standard deviation of the study sample age, height, weight, and body mass index were 66.9 ± 4.09 years, 158.4 ± 6.1 cm, 74.6 ± 7.1 kg, and 29.6 ± 1.9 kg/m2, respectively. The mean, standard deviation and median of the knee flexion ROM and Arabic-KOOS-PS Questionnaire score were 100.7 ± 7.9, 101.5 and 12.9 ± 13.7, 13.4. The non-parametric Spearman correlation coefficient between the knee stiffness and KOOS-PS physical activities resulted very strong positively correlation, r = 0.967.Conclusion: A strong positive correlation has been found between hidden knee disability and ritual physical activities among male cohorts in Saudi cultural community with knee OA
Types of water discharge engineering systems of railway complexes
Authors: Teplykh Svetlana Yu. , Bukhman Nikolai S.
Published: February 2022

The article examines natural-technogenic complexes, in particular, introduces a new concept railway natural-technogenic complex (RNTC), which consists of two main parts natural and technogenic. The article also defines: the structure of the RNTC, the boundaries of the natural-industrial railway system and the system for differentiating the elements of the railway natural-technogenic complexes, which includes the main classification parameters and characteristics. The proposed system for differentiating railway natural-technogenic complexes into structural elements makes it possible to develop a directed scheme for determining and eliminating the causes of the influence of surface wastewater, their collection, removal and subsequent treatment in accordance with the Water Code.
QUALIDADE DE VIDA DE MULHERES APÓS HISTERECTOMIA RADICAL
Authors: Rezer Fabiana , Oliveira Isabel Silva , Faustino Wladimir Rodrigues
Published: February 2022

O Câncer de Colo de Útero é comum na população feminina, implicando na necessidade de realizar histerectomia, total ou parcial do Útero.  Objetivou-se avaliar a qualidade de vida de mulheres que realizaram histerectomia radical após câncer de colo uterino. Trata-se de uma pesquisa descritiva, exploratória e com abordagem quantitativa. O estudo tomou como objeto 15 mulheres que fizeram histerectomia radical decorrente do câncer de colo uterino. Foram coletados dados utilizando o instrumento World Health Organization Quality of Life Group para avaliação da qualidade de vida e, após submissão ao Comitê de Ética e Pesquisa com Seres Humanos, obteve-se a aprovação. Os resultados mostraram que o domínio físico apresentou insatisfação no quesito energia do dia a dia (2,0). O domínio psicológico demonstrou insatisfação na memória, pensar e aprender (2,1). Domínio das relações sociais o quesito menor avaliador foi a atividade sexual (3,0). Domínio do meio ambiente o item menos satisfatório foi o acesso ao serviço de saúde (1,7). Na soma dos domínios percebe-se que o domínio das relações sociais (3,1), seguido do domínio meio ambiente (3,5), apresentaram os piores índices. Já os domínios físicos (4,1) e psicológico (4,0) tiveram as melhores avaliações. Com isso, o estudo aponta que a histerectomia é um evento que repercute na qualidade de vida das mulheres, com atenção especial as relações sociais.
Hybrid war discourse: from history to the present
Authors: Yudko L. V. , Dumanska V.О. ,   National Academy of the Security Service of Ukraine
Published: February 2022

The article comprehensively explores the historical aspect of the phenomenon of “hybrid war”: from its first manifestations in ancient times to the present – the period of formation of Ukrainian statehood. The works are analyzed and the main views of domestic, Russian and American scientists on the essence and the concep of “Hybrid war” are highlighted. It was determined that the phenomenon of hybrid warfare was also traced in the history of domestic state formation at the beginning of the last century. To seize power in Ukraine, the Russian Bolsheviks used many tricks and political maneuvers that had a hybrid component. In particular, one of such methods was the formation of quasi-state formations, such as: Donetsk-Kryvyi Rih Soviet Republic (1918) and others. In addition, the methods used by the Bolsheviks to spread misinformation were analyzed, such as the distribution of free leaflets at the front, which carried a propaganda content. Special attention is paid to the hybrid aggression of the Russian Federation in the XXI century, in particular against Ukraine. The main views of Russian researchers on hybrid warfare are highlighted. They emphasize that the main components of a hybrid war are information warfare, as well as covert involvement of outside armed groups and organizations to solve the problems of interstate confrontation. Also, various definitions of “hybrid war” in terminological dictionaries were analyzed, such as: Dictionary of the Ukrainian language, Cambridge Dictionary, Collins Dictionary. Thanks to a comprehensive study of views on the concept of “hybrid war”, its basic definition was formed, which comprehensively characterizes both historical and contemporary aspects of this phenomenon.
Study of hydrogen internal combustion engine vehicles based on the whole life cycle evaluation method
Authors:   School of Mechanical Engineering, North China University of Water Resources and Electric Power, Zhengzhou, Henan 450045, China, Guo Ping , Xu Jianlun , Zhao Chuanhao , Zhang Baoliang
Published: February 2022

In order to better achieve the goal of low carbon emissions from vehicles, a whole life cycle assessment of hydrogen-fueled internal combustion engine vehicles has been conducted in recent years. Based on the study of hydrogen use around the world, we studied the emission and economic performance of hydrogen-fueled internal combustion engine vehicles from the beginning of hydrogen production to the end of use (Well-to-Wheel, WTW) based on the whole life cycle evaluation method. The results show that the overall environmental impact of hydrogen production by steam reforming of natural gas is the smallest, and that the rational use of "abandoned electricity" for hydrogen production from electrolytic water in the western part of China significantly reduces the overall environmental impact and the cost of hydrogen production. In the use phase, the emissions are less, which not only can meet the National 6 emission standard, but also can reach higher emission standard after adding exhaust gas recirculation (EGR). From the whole life cycle point of view, hydrogen-fueled internal combustion engine has a very good development prospect.
Support Vector Machine-Based Rapid Magnitude Estimation Using Transfer Learning for the Sichuan–Yunnan Region, China
Authors: Zhu Jingbao , Li Shanyou , Ma Qiang , He Bin , Song Jindong
Published: February 2022

The Sichuan–Yunnan region is a seismically active area. To explore the feasibility of using the support vector machine (SVM) method for magnitude estimation in the area and to improve the rapid magnitude estimation accuracy, we construct an SVM magnitude estimation model using transfer learning (TLSVM-M model) based on a single-station record in this study. We find that the magnitude estimation of a single station shows that for the test dataset, within the 3 s time window after the P-wave arrival, the average absolute error (which reflects the size of the estimated magnitude error as a whole) and standard deviation (which reflects the scatter of magnitude estimation error) of the magnitudes estimated by the TLSVM-M model are 0.31 and 0.41, respectively, which are less than those of the SVM magnitude estimation model without transfer learning (0.44 and 0.55, respectively), the τc method (1.35 and 1.74, respectively) and the Pd method (0.44 and 0.56, respectively). In addition, in test involving five earthquake events via the TLSVM-M model, at 1 s after the first station is triggered, the magnitudes of three events (Ms 4.2, 5.2, and 6.3) are estimated within an error range of ±0.3 magnitude units. For the other two earthquakes (Ms 6.6 and 7.0), there is an obvious magnitude underestimation problem at 1 s after the first station is triggered, with less underestimation by increasing time after the first station is triggered. Meanwhile, for these two events (Ms 6.6 and 7.0), within 13 s after the first station was triggered, the magnitude estimation errors are both within ±0.3 magnitude units. The TLSVM-M model has the capability of rapid magnitude estimation for small-to-moderate events in the Sichuan–Yunnan region. Meanwhile, we infer that the proposed model may have potential in earthquake early warning.
On the (Possible) Moral Meaning of the Beautiful in Kant
Authors: Guimarães Rômulo Eisinger
Published: February 2022

With his Critique of Judgment, Kant aimed to establish a connection between the Understanding, concerning the sensibly cognizable, and Reason, concerning the domain of the intelligible, completing, thus, his critical system of Reason. However, to establish this bridge over the “incalculable gulf fixed between the domain of the concept of nature […] and the domain of the concept of freedom, as the supersensible” is not as easy as it may seem: since each of these faculties has its own ground, it is not legitimate for us to establish a direct link between the sensible and the intelligible. Thus, even when Kant claims “beauty as a symbol of morality” one cannot link Ethics and Aesthetics if not at a transcendental level, merely by an analogy between their forms of reflection. It is only by analogy that we can hope to find moral significance in (the beautiful forms of) nature – but that does nothing to reduce the importance of this significance for the Kantian system (especially with regard to the fulfilment of the dispositions of a rational being in the sensible world). This paper dwells on the Kantian doctrine of symbolization of morality and the (possible) moral meaning of the beautiful on nature.
Percepción de la sexualidad en la titulación de Trabajo Social
Authors: Varea Correa Leyre
Published: February 2022

La sexualidad es un valor humano que nace con la vida misma; Es el modo de vivirse, verse y sentirse como persona sexuada. No obstante, a pesar de considerarse un eje vertebrador de la vida de las personas, es un ámbito que no se está abordando de manera integral ni desde los centros educativos ni desde los hogares, provocando una distorsión de la información sobre sexualidad en la población joven. En este estudio se contextualizan las competencias de una muestra de 112 estudiantes de la titulación de Trabajo Social sobre la Educación Sexual Integral.
Crónica del Seminario de mediación en conflictos laborales y mediación simulada. Evolución de la solución autónoma de conflictos laborales en La Rioja
Authors: Rábanos Martínez Jorge
Published: February 2022

El presente artículo relata la crónica de las jornadas “La solución autónoma del conflicto laboral como instrumento para el trabajo decente” que se llevaron a cabo en la Universidad de La Rioja en los meses de mayo y junio de 2021. Además, se muestra la evolución de los datos sobre la solución autónoma de conflictos laborales en La Rioja.
Connexa: No. 12: Noviembre, 2021: Síntesis de información y datos sobre integración y comercio
Authors:   Instituto para la Integración de América Latina y el Caribe
Published: February 2022

Con nuevo formato y contenido, el presente Newsletter se centra en la recuperación y el futuro de la región, con sus oportunidades y desafíos. En esta edición se hace un repaso sobre el estado del comercio mundial de bienes, la recuperación del intercambio de servicios y la mejora de la inversión extranjera directa en América Latina y el Caribe. Además, se desarrolla sobre el estado de los acuerdos de comercio e integración de la región y se relevan noticias y publicaciones de interés.
Leukocytoclastic Vasculitis
Authors: Vasireddy Anila , Pai Kanthilatha , Shetty Varsha M , Acharya Raviraja V , Kusugodlu Ramamoorthi , Doddamani Akhila , Madhyastha Sharath P
Published: February 2022

Scrub typhus is a disease endemic to the Indian subcontinent caused by the obligate intracellular pleomorphic organism, Orientia tsutsugamushi. Scrub typhus, among other acute febrile illnesses, manifests as prodromal symptoms of fever, malaise, myalgia and anorexia followed by a distinct maculopapular rash, hepatosplenomegaly and lymphadenopathy. We report the case of a patient presenting to tertiary care hospital in southern India in 2021 who developed a rare cutaneous vasculitis secondary to infection with Orientia tsutsugamushi. After performing the Weil-Felix test, a diagnostic titre of >1:640 against OXK was obtained. Furthermore, a skin biopsy was carried out which confirmed the diagnosis of leukocytoclastic vasculitis. The patient was treated with doxycycline and showed drastic improvement in his symptoms.
Keywords: Scrub Typhus, Rickettsia; Vasculitis; Doxycycline; India.
Searching for cultural, historical, ethical and philosophical roots of sport in archaic and classical Greek philosophy
Authors: Sagat Peter , Ambrozy Marian
Published: February 2022

Already the Homeric period meant a high social status for successful athletes. However, it was exclusive; it excluded those whose time was needed to work for a living. Democratization in Athens and the militarization of sport in other fields had brought the spread of sport to the wider classes. Xenophanes became the first critic of the sport as a philosopher. Sophists, in turn, emphasized the importance of educational training for life, including sports education. Although the character of the historical Socrates is problematic, it is generally believed that Socrates left behind the legend of a physically immensely disposed, resilient man. Plato consolidated the role of sport through his role in social philosophy. Specifically, he spoke of the importance of the virtue ἀνδρεία. Although Aristotle characterizes kalokagathia and defined the role of sport within virtues, he was critical in its evaluation. He refused to practice sports if it led to a deterioration of the body. Partly archaic, especially classical Greek philosophy provided a theoretical rationale for recognizing sport as a meaningful activity, but also its critique.
Audiological differences in healthy individuals with generalized joint hypermobility: a case-control study
Authors: TAŞ Memduha , TUNA Filiz , YILMAZ Şüle
Published: February 2022

Objectives: Despite the prevalence of generalized joint hypermobility (GJH), the audiological functions of individuals with GJH have not been documented. This study aimed to investigate audiological findings in individuals with GJH.
Methods: This observational, cross-sectional, controlled study was conducted between May 2017 and August 2017. The mean age of all participants was 20.25 ± 0.75 years (range: 19-22 years). The generalized joint hypermobility consisted of individuals with a Beighton score of ≥ 5, while the controls with a Beighton score of ≤ 4. Pure-tone audiometry, immittance audiometry, and Transient Evoked Otoacoustic Emsission (TEOAE) testing were performed on subjects with generalized joint hypermobility (n = 25, mean age: 20.24 ± 0.72 years) and sex- and age-matched healthy controls (n = 31, mean age: 20.26 ± 0.77 years).
Results: There were no significant differences in the mean hearing thresholds between the groups, although six (5.4%) ears in the GJH group had thresholds > 15 dB at one (five ears) or more frequencies. Significant differences were detected between the groups in the left ear for TEOAEs at 4 kHz and acoustic reflex thresholds.
Conclusions: Individuals with GJH have some audiological differences that may be a predictor of changes related to future hearing loss. Further studies that involve larger samples and include participants of different ages are needed in order to determine whether individuals with GJH are more prone to hearing loss.
A Nurse-Led Home Disaster Preparedness Intervention for New Parents
Authors: Heagele Tara N. , Nurse-Clarke Natasha J.
Published: February 2022

Purpose

To evaluate the effectiveness of a nurse-led intervention on the household emergency preparedness (HEP) level of parents with newborns and describe the nurses' perceived facilitators/barriers to providing this intervention.

Design

A non-randomized, non-blinded, quasi-experimental pilot study conducted with maternal/child nurses and neonatal parents. The intervention used an educational booklet on what is needed to prepare for disasters and how to develop evacuation and communication plans. Parents completed booklets during their infant's hospital stay, after which they received a free disaster kit from the nurses.

Sample

68 parents, 13 maternal/child nurses.

Main Outcome Variable

Level of HEP.

Results

HEP scores increased from 4.75 to 10.66 out of 11 from pre- to post-intervention (p < .001). Barriers to implementing this intervention included the weight of the disaster kit, parent anxiety, and need for follow-up with parents. Facilitators included the booklet, disaster kit, and speed/cost of the intervention.
Knowledge Sharing, Individualism, Collectivism, and Organizational Innovative Behaviour in Public Health Organizations
Authors: Asif Tasneem Khawaja , Qureshi Saba Feroz
Published: February 2022

This paper focuses on investigating the more innovative employees, i.e., individualists or collectivists, in the public sector when it comes to knowledge sharing and organizational culture. The study adopted quantitative research technique and data was collected through an online survey. A field study was conducted and data was obtained from 480 employees working in Pakistan's two major public health institutions so as to test the study's hypotheses. A hierarchical linear regression model was used to test the hypotheses. The results show that there is a significant positive influence of organizational-based knowledge sharing, individual-based knowledge sharing, collectivism, and individualism on organizational innovative behaviour in the organizations. This study also found a significant positive impact of collectivism and individualism as moderators on organizational innovative behaviours. The study further concluded that collectivism has a higher positive impact on organizational innovative behaviour in comparison to individualism.
Representaciones en torno al concepto Independencia en los inicios de la prensa paraguaya (1845-1852)
Authors: Baratta María Victoria
Published: February 2022

El presente trabajo propone analizar los conceptos políticos  y representaciones desplegados en torno a la búsqueda del reconocimiento de la independencia de Paraguay por parte de la Confederación Argentina. La fuente elegida es la prensa, ámbito privilegiado del debate político. Nos concentraremos en el estudio de El Paraguayo Independiente, primer periódico de Paraguay que fue creado durante el gobierno de Carlos Antonio López en 1845. Su redactor principal fue el mismo presidente paraguayo. La dificultad inicial de definir el concepto Independencia en Paraguay fue una parte relevante de los conflictos diplomáticos con sus vecinos y los antecedentes de la gran guerra.
Population growth of a generational cohort of the copepod Apocyclops panamensis (Marsh, 1913) under different temperatures and salinities
Authors: Cruz-Rosado Leonardo , Contreras-Sánchez Wilfrido Miguel , Hernández-Vidal Ulises , Perez-Urbiola Juan Carlos , Contreras-García María de Jesús
Published: February 2022

This study was carried out to identify the effects of salinity and temperature during Apocyclops panamensis culture, fed with Tetraselmis chuii. The experiment was conducted in laboratory conditions for 14 days. Nauplii from the same cohort were used to start the experiment, using a density of 1 ind mL−1 in a volume of 400 mL. The feed consisted of a daily supply of 20 000 cell mL−1 of microalgae. Nine treatments with three replicates were evaluated (24◦C-28h, 24◦C-32h, 24◦C-36h, 28◦C-28h, 28◦C-32h, 28◦C-36h, 32◦C-28h, 32◦C- 32h and 32◦C-36h). The factorial ANOVA indicates that temperature had a significant effect on the abundance of total copepods at day 14 (p = 0.02), while salinity did not show a significant effect (p = 0.06) on the total population of A. panamensis. Significant effects of temperature (p < 0.01) and salinity (p < 0.001) were observed for the nauplii population. The best growth of the entire population was reached in the treatment 32◦C-28h, with a population of 1 380.95 (± 1 267.06 ind L−1 (± 1 267.06) at the end of the experiment. Treatments 32◦C-28h and 32◦C-32h produced the highest average population of nauplii and copepodites at the end of the experiment. Adult females presented the greatest abundance in the 32◦C-32h treatment with 214.29 ind L−1, adult males increased between days 11 and 14 in treatments 24◦C-28h, 32◦C-28h, and 32◦C-32h without exceeding 170 ind L−1. In this study, it is evident that A. panamensis prefers warm temperatures and brackish environments.
A AMP Agradece!
Authors: Guimarães Miguel , Villanueva Tiago
Published: February 2022

N/a.
Perioperative Management of Patients with Rheumatic Diseases: Glucocorticoids, DMARDs, Biological Agents and NSAIDs
Authors: Lyalina V. V. , Borisovskaya S. V. , Skripnichenko E. A. , Ettinger O. A. , Padzheva T. M. , Nikitin I. G.
Published: February 2022

The rheumatic patients are characterized by various structural and functional changes, caused by chronic disease the necessity of constant medication intake, including anti-inflammatory drugs and immunosuppressants. In this regard, the rheumatic patients have an increased risk of intraoperative and postoperative complications. The purpose of this publication is to review current recommendations on the topic of perioperative management of rheumatic patients. The publication consists of two parts. In the first part we review the issues of perioperative administration of steroids, disease-modifying antirheumatic drugs, biologics and nonsteroidal anti-inflammatory drugs.
Regulation of the Immune System in Aging: Focus on Epigenetic Mechanisms
Authors: Aitbaev K. A. , Murkamilov I. T. , Murkamilova Zh. A. , Kudaibergenova I. O. , Yusupov F. A.
Published: February 2022

Epigenetics studies processes leading to changes in the activity of genes without changing the DNA sequence. Epigenetic mechanisms, such as DNA methylation and histone modifications, are formed during embryonic development, and epigenetic profiles are stably inherited in mitosis, providing cell differentiation and their further fate in the development process. Under the influence of internal and external factors such as metabolic profile, hormones, nutrition, drugs, smoking and stress, epigenetic mechanisms are actively modulated and, in this sense, a lifestyle can significantly affect the epigenome, and consequently, the gene expression profile and function of cells. It is shown that the development and function of cells of both congenital and adaptive immune systems are also regulated by epigenetic mechanisms, and negative epigenetic changes are a distinctive feature of aging and cancer. Given these data, it can be assumed that age-related changes in the profile of epigenetic labels can lead to a decrease in immune function and contribute to an increase in morbidity in the elderly. Therefore, to ensure healthy aging, better understanding of how to avoid epigenetic changes that are associated with aging of the immune system is needed. In this review, we tried to generalize the latest achievements in this field of research and consider the possibility of using them for diagnosis, prevention and treatment of diseases.
Risk Factors Promoting Early Cardiovascular Structure Disorders in Patients with Primary Hypothyroidism
Authors: Nikolaeva A. V. , Pimenov L. T. , Sufiyanov V. G. , Dudarev M. V.
Published: February 2022

Objective. To develop the pattern of early cardiovascular disorders in patients with primary hypothyroidism based on the analysis of relationship between patient’s thyroid status and some functional cardiovascular parameters depending on compensation status. Materials and methods. The examination of 163 women aged 62 [55;67] years with primary hypothyroidism was performed. The patients were divided into groups: 1 group included 54 patients aged 62.0 [57;68] years with subcompensated disease, 2 group consisted of 15 patients aged 59 [53;66] years with non-compensated disease and 3 group included 94 patients aged 63 [53;66] years with compensated hypothyroidism. Physical examination, transthoracic echocardiography, assessment of global left ventricle longitudinal strain by speckle tracking method, endothelial function and laboratory tests were performed to all patients. Regression analysis using thyroid stimulating hormone, free T4, age, duration of the disease, cause of hypothyroidism, menopause presence and natural thyroid stimulating hormone logarithm as predictors and some cardiovascular parameters of heart condition and lipid metabolism as dependent valuables was made. Results. Mathematic modeling demonstrated that the combination such factors as age, duration of disease and thyroid stimulating hormone level is the most important in left ventricle remodeling processes. However, the age only has significant influence on intima media thickness. Conclusion. Left ventricle remodeling, morphologic functional status of blood vessel wall and decrease of glomerular filtration rate are basically determined by such modified and non-modified factors as body mass index, age, duration of hypothyroidism and thyroid stimulating hormone level.
Robust Beamforming Based On Graph Attention Networks For IRS-assisted Satellite IoT Communications
Authors: Cao Hailin , Zhu Wang , Feng Wenjuan , Fan Jin
Published: February 2022

Satellite communication is expected to play a vital role in realizing Internet of Remote Things (IoRT) applications. This article considers an intelligent reflecting surface (IRS)-assisted downlink low Earth orbit (LEO) satellite communication network, where IRS provides additional reflective links to enhance the intended signal power. We aim to maximize the sum-rate of all the terrestrial users by jointly optimizing the satellite’s precoding matrix and IRS’s phase shifts. However, it is difficult to directly acquire the instantaneous channel state information (CSI) and optimal phase shifts of IRS due to the high mobility of LEO and the passive nature of reflective elements. Moreover, most conventional solution algorithms suffer from high computational complexity and are not applicable to these dynamic scenarios. A robust beamforming design based on graph attention networks (RBF-GAT) is proposed to establish a direct mapping from the received pilots and dynamic network topology to the satellite and IRS’s beamforming, which is trained offline using the unsupervised learning approach. The simulation results corroborate that the proposed RBF-GAT can achieve approximate performance compared to the upper bound with low complexity.
Analysis Of Ac Magnetic Susceptibility Data Of A Room Temperature Superconductor
Authors: Hirsch Jorge
Published: February 2022

In Ref. [1] Snider et al reported room temperature superconductivity in carbonaceous sulfur hydride (CSH) under high pressure. Recently the data for the temperature dependent ac magnetic susceptibility shown in figures of Ref [1] have appeared in the form of tables corresponding to different pressures [2]. Here we provide an analysis of the data for a pressure of 160 GPa. This work was performed in collaboration with D. van der Marel.
Subluxation in the Arthritic Shoulder
Authors: Matsen Frederick A. , Hsu Jason E.
Published: February 2022

» The term “subluxation” means partial separation of the joint surfaces. In the arthritic shoulder, “arthritic glenohumeral subluxation” refers to displacement of the humeral head on the surface of the glenoid.

» The degree of arthritic glenohumeral subluxation can be measured using radiography with standardized axillary views or computed tomography (CT).

» Shoulders with a type-B1 or B2 glenoid may show more posterior subluxation on an axillary radiograph that is made with the arm in an elevated position than on a CT scan that is made with the arm at the side.

» The degree of arthritic glenohumeral subluxation is not closely related to glenoid retroversion.

» The position of the humeral head with respect to the plane of the scapula is related to glenoid retroversion and is not a measure of glenohumeral subluxation.

» Studies measuring glenohumeral subluxation before and after arthroplasty should clarify its importance to the clinical outcomes of shoulder reconstruction.
Breeding Swainson’s Hawks in the Central Coast Range of California
Authors: Klein Stephanie , Baer Larry , Phillips Ryan A.
Published: February 2022

During the 20th century the Swainson’s Hawk (Buteo swainsoni) was an infrequent migrant through the central Coast Range of California with no breeding documented. Since 2005, however, several breeding pairs have established nest sites in the region. We studied Swainson’s Hawks during the breeding seasons of 2019 and 2020 in a portion of the central Coast Range to estimate their abundance and distribution there. We observed individual hawks systematically and monitored their nesting activity and breeding outcomes in suitable habitat in Alameda, Santa Clara, and San Benito counties within the Coast Range and sought to characterize the habitat of this small outlying population. From 2019 to 2020 the numbers of nesting pairs increased from 3 to 5, of young fledged from 1 to 6, and of individual adults from 15 to 22. Swainson’s Hawks were more closely associated with farmland than with grassland, and nests were located in areas that were closely associated with both grassland and farmland. The increase of this species in the central Coast Range and its use of agricultural areas is of conservation significance for land managers and wildlife and conservation agencies, given that the California Department of Fish and Wildlife has designated it as threatened.
Computationally designed ssDNA modular nanorobots for cancer recognition, toehold disintegration, visual diagnosis and synergistic gene silencing
Authors: Shen Xiaotong , Ouyang Qingwen , Tan Hongwei , Ouyang Jin , Na Na
Published: February 2022

Single-stranded DNA (ssDNA) allows more flexible and directional modifications than relatively rigid double-stranded DNA (dsDNA) in a ‘side-by-side’ manner. However, ssDNA applications are greatly limited by their poor stability from the ‘atom equivalents’ design, suffering from increased folding errors and complicated sequence optimizations. Herein, via all-atom molecular dynamics (MD) simulations, a molecular dynamics simulation of the dynamic folding of ssDNA in the self-assembly process was examined and optimized. This guided the intelligent construction of a stable frame structure of tetrahedral ssDNA modular nanorobots, which are convenient for diagnosis and therapy applications. The ssDNA modular nanorobots were assembled with five functional modules, which included tetrahedron skeleton fixation, tumour cell membrane protein dual recognition, enzyme loading, dual-targeted miRNA detection and synergy siRNA loading. As demonstrated, the ssDNA modular nanorobots were stable, flexible, and highly utilized, and had low folding errors. For intracellular delivery, a two-aptamer logic gate was constructed for tumour cell membrane protein dual recognition, obtaining efficient and cancer-selective internalization of ssDNA nanorobots with reagent loading. Then, in cancer cells with high expression of target miRNAs (miR-21 and miR-224), toehold disintegration was initiated by two RCA reactions for precise and visualized dual detection. Simultaneously, the released disintegrated modules triggered synergistic gene silencing by two loaded siRNAs, which resulted in a 95.6% cure rate in 17 days. This work has provided a computationally designed pathway for constructing flexible ssDNA modular nanorobots, showing better multiflexibility and applicability than relatively rigid dsDNA nanostructures.
Identification of Key Genes Associated With Radiotherapy Resistance in Cervical Cancer by Bioinformatics
Authors: Zhang zhenhua , Xiang kechao , Tan longjing , Du xiuju , He huailin , Li dan , Wen qinglian , Li li
Published: February 2022

Background: Cervical cancer is one of the common malignant tumors in women, among which squamous cell carcinoma of the cervix accounts for more than 90%. Currently, 30% of patients with intermediate to advanced squamous cervical cancer are still uncontrolled or recurrent after standard radical simultaneous radiotherapy; therefore, the search for key genes affecting the sensitivity of radiotherapy may lead to new strategies for treatment.Methods: Differentially expressed genes were identified by GEO2R from the gene expression omnibus (GEO) website, prognosis-related genes for cervical cancer were obtained from other databases, then gene ontology (GO) was analyzed by DAVID. Meanwhile, protein-protein interaction network was constructed by STRING, By Online analysis of differentially expressed genes, prognostic genes, and CCDB(cervical cancer gene database website: http://crdd.osdd.net/raghava/ccdb/index.php) through the OncoLnc database, we aim to search for differentially expressed genes associated with prognosis validation by immunohistochemistry.Result: 298 differentially expressed genes, 724 genes associated with prognosis were found. Eventually, 2 genes, ASPH and NKAPP1, were identified through validation as genes that affect both sensitivities to radiotherapy and survival. Then, immunohistochemical results showed that the ASPH gene was indeed highly expressed in the radiotherapy-resistant group and had lower OS and PFS.Conclusion: This study aims to better understand the characteristics of cervical cancer radiation therapy resistance-related genes through bioinformatics, and provide further research ideas for finding new mechanisms and potential therapeutic targets related to cervical cancer radiation therapy.
Development of a Nomogram for Predicting the Occurrence of Symptomatic Intracranial Haemorrhage after Thrombectomy: A Single-Center Retrospective Observational Study
Authors: Wang YunHui , Tu Qi , Zhao TingTing , Ye Qiang , Zheng Kuang , Zhang WeiZhong , Li ZeQun
Published: February 2022

Background
Symptomatic intracranial haemorrhage (SICH) is a severe and deadly complication in patients with large vessel occlusion (LVO) who receive endovascular treatment (EVT). Recent studies have indicated that many risk factors, including pretreatment scores and the operation process, may be associated with the occurrence of SICH after thrombectomy. This study aims to identify independent risk factors and establish a novel nomogram-based model for patients with anterior LVO to predict the occurrence of SICH after direct thrombectomy or bridge therapy (thrombectomy based on intravenous thrombolysis).
Methods
Patients with acute ischaemic stroke after EVT to recanalize the blocked artery in anterior circulation were consecutively recruited from November 2017 to March 2019. Baseline information was collected from each patient. These data were subsequently analysed by R Project for Statistical Computing.
Results
A total of 127 patients with complete data were classified into the training set, among whom 37 patients (29.1%) fulfilled the criteria for SICH. The results of the multivariate analyses showed that NIHSS (P=0.024), ASPECT (P<0.001) and ASITN (P=0.017) scores were independently associated with the occurrence of SICH after thrombectomy. Ultimately, three independent pretreatment predictors were included in the NIHSS/ASPECT/ASITN (NAA) prediction model, and the receiver operating characteristic analysis results showed an area under the curve (AUC) of 0.845 (95% CI=0.763–0.928). The calibration plots showed that the actual observations were consistent with the measured and predicted results of the nomogram.
Conclusions
In this study, a novel model based on NAA for predicting the occurrence of SICH after thrombectomy in patients with anterior LVO was established and validated internally. The results suggest that this model can help improve perioperative evaluations and individualized treatment strategies.
Body Image Distress among Cancer Patients: Needs for Psychosocial Intervention Development
Authors: N/A Nikita , Rani Ruchika , Kumar Rajesh
Published: February 2022

Objectives: This study examines the body image associated distress among patients with head and neck cancer visiting a tertiary care hospital for follow-ups.Design: An exploratory, cross-sectional design enrolled 170 patients with head and neck cancer purposively undergone cancer surgery at a newly established tertiary care hospital, North India. Methods: A structured pre-tested socio-demographic and clinical profile checklist and the Derriford Appearance Scale 24 (DAS-24) were used to collect information. An appropriate descriptive and inferential statistic was applied to compute the findings. Results: The mean age of the participants was 47.98 (SD=12.1) years, and 80% of the participants were unemployed. The mean body image distress score was 57.95 (SD=10.3, 47-66.75, range 42-77). The body image distress found a significant association with age (p<.001), gender (p=0.003), and working status of the patients (p=0.032). Multilinear regression reported gender as an independent predictor (95% CI: 0.615 - 8.646, p=0.025) for body image distress in patients.Conclusions: Patients with head and neck cancer have significant psychosocial distress due to changes in body appearance. Female patients who had undergone surgery at young age reported higher distress. We should include body image and rehabilitation in the daily care of patients. Recommending the use of cosmetic surgery on routine follow-ups is another strategy to improve facial appearance to overcome the negative impact of body image.
Study on Collapse Mechanism and Treatment Measures of Portal Slope of a High-speed Railway Tunnel
Authors: Hu Guoping , Xia Yingzhi , Zhong Lianggen , Ruan Xiaoxue , Wang Qingguo
Published: February 2022

The slope of an open cut tunnel is located above the exit of the Leijia tunnel on the Changgan high-speed railway. During the excavation of the open cut tunnel foundation pit, the slope slipped twice, a large landslide of 92500 m³ formed. The landslide body and unstable slope body not only caused the foundation pit of the open cut tunnel to be buried and the anchor piles to be damaged but also directly threatened the operational safety of the later high-speed railway. Therefore, to study the stability change in the slope of the open cut tunnel under heavy rain and excavation conditions, a 3D numerical calculation model of the slope is carried out by Midas GTS software, the deformation mechanism is analyzed, anti-sliding measures are proposed, and the effectiveness of the anti-sliding measures is analyzed according to the field monitoring results. The results show that when rainfall occurs, rainwater collects in the open cut tunnel area, resulting in a transient saturation zone on the slope on the right side of the open cut tunnel, which reduces the shear strength of the slope soil; the excavation at the slope toe reduces the anti-sliding capacity of the slope toe. Under the combined action of excavation and rainfall, when the soil above the top of the anchor pile is excavated, two potential sliding surfaces are bounded by the top of the excavation area, and the shear outlet is located at the top of the anchor pile. After the excavation of the open cut tunnel, the potential sliding surface is mainly concentrated at the lower part of the downhill area, and the shear outlet moves down to the bottom of the open cut tunnel. Based on the deformation characteristics and the failure mechanism of the landslides, comprehensive control measures, including interim emergency mitigation measures and long-term mitigation measures, are proposed. The field monitoring results further verify the accuracy of the anti-sliding mechanism analysis and the effectiveness of anti-sliding measures.
Optimization of Phosphate Oxygen Isotope Pretreatment Measurement Method Based on Hosphate In-situ Enrichment Blanket
Authors: Li Sumei , Du Chengyu , Jin Xin , Yang Jing , Zhang Wei , Li Simin
Published: February 2022

Phosphate oxygen isotope analysis is an effective tool for investigating phosphorus migration and transformation in water bodies. However, existing pretreatment methods for this technology are severely restricted by large sample requirements, cumbersome operation, and poor applicability. To optimize the pretreatment method, hydrated zirconia was prepared by liquid-phase precipitation. Zeolite, D001 macroporous resin, activated carbon, and ceramsite were selected as potential support materials. The optimum zirconium support material was selected after field enrichment and laboratory elution experiments. The optimum in situ enrichment time, material dose, and elution time were determined using response surface methodology. The D001 resin provided the best selective adsorption and elution capacity for phosphate. The optimum parameters for an in situ phosphate-enrichment blanket were obtained by response surface optimization as a zirconium-loaded D001 resin mass of 13 g, enrichment time of 360 min, and elution time of 853 min. After purification, a bright yellow Ag3PO4 solid was obtained. The results showed that the optimization method was reliable. These results provide a foundation for the application of phosphate oxygen isotope analysis in freshwater bodies.
Genetic Characterization of Rare Bruconha Virus (Bunyavirales: Orthobunyavirus) Isolated in Vale Do Ribeira (Atlantic Forest Biome), Southeastern Brazil
Authors: Costa Antonio Charlys da , Morais Vanessa dos Santos , de Azevedo Roberta Marcattti , Nuevo Karolina Morales Barrio , Cunha Mariana Sequetin
Published: February 2022

Brazil is a great source of arbovirus diversity, mainly in the Amazon Region. However, other biomes, especially Atlantic Forest, may be also a hotspot for emergent viruses, including Bunyaviruses (Negarnaviricota: Bunyavirales). For instance, Vale do Ribeira, located in the Southeastern region, has been widely studied for virus surveillance, where Flavivirus, Alphavirus and Bunyaviruses were isolated during the last decades, including Bruconha virus (BRCV), a member of Orthobunyavirus genus Group C, in 1976. Recently, a new isolated of BRCV, named Span321532, was obtained from an adult sentinel mice placed in Iguape county, in 2011, and a full-length genome was generated, with nucleotide differences that varied from 1.5%, 5.3% and 5% (L, M and S segments respectively) from the prototype isolated 35 years earlier. Although no evidence of reassortants were detected, this findings reiterates the need for new surveillance and genomic studies in the area considering the high mutation rates of arbovirus and also to identify the hosts capable of supporting the continuous circulation of Orthobunyavirus.
A Comparative Analysis of Health Status of International Migrants and Local Population in Chile: a Population-based, Cross-sectional Analysis From a Social Determinants of Health Perspective
Authors: Rada Isabel , Oyarte Marcela , Cabieses Baltica
Published: February 2022

Background: During recent decades intraregional migration has increased in Latin America. Chile became one of the main receiving countries and hosted diverse international migrant groups. Evidence have suggested a healthy migrant effect (HME) on health status but remains scarce, controversial and needs to be updated. This study performed a comprehensive analysis verifying the existence of HME and its association with social determinants of health (SDH). Methods: We analyzed data from the Chilean National Socioeconomic Characterization Survey (CASEN, version 2017). Crude prevalence of health status indicators such as negative self-perceived health, chronic morbidity, disability and activity limitations were described in both international migrants and local population. The association between these outcomes and demographic, socioeconomic, access to health care, psychosocial and migratory related factors were tested using multivariate logistic regression in each population. The HME was also tested using multivariate logistic regression, sequentially adjusted for each set of SDH to obtain the odds ratio of presenting each health outcome if being an international migrant (ref=Chilean). Results: International migrants had lower crude prevalence of all health indicators than Chileans. Age, unemployment and health care system affiliation were associated with health outcomes in both populations. Psychosocial determinants were both risk and protective factors. Crude analysis revealed an apparent HME in all health outcomes. After adjustment for each set of SDH, the immigrant health advantage was only significant for chronic morbidity. Being migrant was associated with 39% lower odds of having chronic diseases compared to locals (OR: 0,61; 95% CI: 0,44-0,84; P = 0,0003). For all other conditions, HME disappeared after adjusting by SDH, particularly unemployment, type of health system and psychosocial factors. Conclusions: Testing the HME in Chile reveals an advantage for chronic morbidities that remained significant after adjustment for SDH. This analysis shed light on health disparities between international migrants and local population in the Latin American region, with special relevance of unemployment, type of health system and psychosocial factors. As well as differential exposures faced during migration process that could dissolve the HME over time. Evidence from this integrative approach is useful for informed health planning and intersectoral local and regional solutions.