bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis of Mesoporous TiO2-B Nanobelts with Highly Crystalized Walls toward Efficient H2 Evolution
Authors: Li Ping , Cao Qing , Zheng Dehua , Alshehri Abdulmohsen Ali , Alghamidi Yousef Gamaan , Alzahrani Khalid Ahmed , Kim Minjun , Hou Jie , Lai Linfei , Yamauchi Yusuke , Ide Yusuke , Bando Yoshio , Kim Jeonghun , Malgras Victor , Lin Jianjian
Published: June 2019

Mesoporous TiO2 is attracting increasing interest due to properties suiting a broad range of photocatalytic applications. Here we report the facile synthesis of mesoporous crystalline TiO2-B nanobelts possessing a surface area as high as 80.9 m2 g−1 and uniformly-sized pores of 6–8 nm. Firstly, P25 powders are dissolved in NaOH solution under hydrothermal conditions, forming sodium titanate (Na2Ti3O7) intermediate precursor phase. Then, H2Ti3O7 is successfully obtained by ion exchange through acid washing from Na2Ti3O7 via an alkaline hydrothermal treatment. After calcination at 450 °C, the H2Ti3O7 is converted to a TiO2-B phase. At 600 °C, another anatase phase coexists with TiO2-B, which completely converts into anatase when annealed at 750 °C. Mesoporous TiO2-B nanobelts obtained after annealing at 450 °C are uniform with up to a few micrometers in length, 50–120 nm in width, and 5–15 nm in thickness. The resulting mesoporous TiO2-B nanobelts exhibit efficient H2 evolution capability, which is almost three times that of anatase TiO2 nanobelts.
Growth, Feeding Tolerance and Metabolism in Extreme Preterm Infants under an Exclusive Human Milk Diet
Authors: Eibensteiner Fabian , Auer-Hackenberg Lorenz , Jilma Bernd , Thanhaeuser Margarita , Wald Martin , Haiden Nadja
Published: June 2019

Background: For preterm infants, human milk (HM) has to be fortified to cover their enhanced nutritional requirements and establish adequate growth. Most HM fortifiers are based on bovine protein sources (BMF). An HM fortifier based on human protein sources (HMF) has become available in the last few years. The aim of this study is to investigate the impact of an HMF versus BMF on growth in extremely low birth weight (ELBW, <1000 g) infants. Methods: This was a retrospective, controlled, multicenter cohort study in infants with a birthweight below 1000 g. The HMF group received an exclusive HM diet up to 32+0 weeks of gestation and was changed to BMF afterwards. The BMF group received HM+BMF from fortifier introduction up to 37+0 weeks. Results: 192 extremely low birth weight (ELBW)-infants were included (HMF n = 96, BMF n = 96) in the study. After the introduction of fortification, growth velocity up to 32+0 weeks was significantly lower in the HMF group (16.5 g/kg/day) in comparison to the BMF group (18.9 g/kg/day, p = 0.009) whereas all other growth parameters did not differ from birth up to 37+0 weeks. Necrotizing enterocolitis (NEC) incidence was 10% in the HMF and 8% in the BMF group. Conclusion: Results from this study do not support the superiority of HFM over BMF in ELBW infants.
Prevention of Allergic Sensitization and Treatment of Cow’s Milk Protein Allergy in Early Life: The Middle-East Step-Down Consensus
Authors: Vandenplas Yvan , Al-Hussaini Bakr , Al-Mannaei Khaled , Al-Sunaid Areej , Helmi Ayesh Wafaa , El-Degeir Manal , El-Kabbany Nevine , Haddad Joseph , Hashmi Aziza , Kreishan Furat , Tawfik Eslam
Published: June 2019

Allergy risk has become a significant public health issue with increasing prevalence. Exclusive breastfeeding is recommended for the first six months of life, but this recommendation is poorly adhered to in many parts of the world, including the Middle-East region, putting infants at risk of developing allergic sensitization and disorders. When breastfeeding is not possible or not adequate, a partially hydrolyzed whey formula (pHF-W) has shown proven benefits of preventing allergy, mainly atopic eczema, in children with a genetic risk. Therefore, besides stimulating breastfeeding, early identification of infants at risk for developing atopic disease and replacing commonly used formula based on intact cow milk protein (CMP) with a clinically proven pHF-W formula is of paramount importance for allergy prevention. If the child is affected by cow’s milk protein allergy (CMPA), expert guidelines recommend extensively hydrolyzed formula (eHF), or an amino acid formula (AAF) in case of severe symptoms. The Middle-East region has a unique practice of utilizing pHF-W as a step-down between eHF or AAF and intact CMP, which could be of benefit. The region is very heterogeneous with different levels of clinical practice, and as allergic disorders may be seen by healthcare professionals of different specialties with different levels of expertise, there is a great variability in preventive and treatment approaches within the region itself. During a consensus meeting, a new approach was discussed and unanimously approved by all participants, introducing the use of pHF-W in the therapeutic management of CMPA. This novel approach could be of worldwide benefit.
A Double-Blind, Randomized, Placebo-Controlled Crossover Clinical Study of the Effects of Alpha-s1 Casein Hydrolysate on Sleep Disturbance
Authors: Kim Hyeon Jin , Kim Jiyeon , Lee Seungyeon , Kim Bosil , Kwon Eunjin , Lee Jee Eun , Chun Min Young , Lee Chan Young , Boulier Audrey , Oh Seikwan , Lee Hyang Woon
Published: June 2019

This study evaluated the effects of alpha-s1 casein hydrolysate (ACH; Lactium®) on the subjective and objective sleep profiles of a community-based sample of Koreans with poor sleep quality. We performed a double-blind, randomized crossover trial with 48 participants (49.0 ± 1.7 years old, 65% female) who exhibited a mild to moderate degree of sleep disturbance. Either ACH or placebo was administered for the initial four weeks, and the counterpart was administered in precisely the same manner after a four-week washout period. Sleep disturbance scales, daytime functioning, and psychiatric aspects showed a similar tendency to improve during both ACH and placebo phases without significant group differences. Overall perceived sleep profiles in sleep diaries were significantly improved during the ACH phase, represented by increased total sleep time and sleep efficiency (SE), as well as decreased sleep latency and wake after sleep onset (WASO). Interestingly, actigraphy demonstrated significantly increased SE after continuous use of ACH for four weeks, clearly more improved when compared to two weeks of use. The polysomnography measures showed a similar tendency without statistically significant group differences. Our findings suggest that refined ACH was well tolerated and could improve sleep quality, with possible cumulative beneficial effects with long-term administration.
Role of ClpP in the Biogenesis and Degradation of RuBisCO and ATP Synthase in Chlamydomonas reinhardtii
Authors: Majeran Wojciech , Wostrikoff Katia , Wollman Francis-André , Vallon Olivier
Published: June 2019

Ribulose 1,5-bisphosphate carboxylase/oxygenase (RuBisCO) associates a chloroplast- and a nucleus-encoded subunit (LSU and SSU). It constitutes the major entry point of inorganic carbon into the biosphere as it catalyzes photosynthetic CO2 fixation. Its abundance and richness in sulfur-containing amino acids make it a prime source of N and S during nutrient starvation, when photosynthesis is downregulated and a high RuBisCO level is no longer needed. Here we show that translational attenuation of ClpP1 in the green alga Chlamydomonas reinhardtii results in retarded degradation of RuBisCO during S- and N-starvation, suggesting that the Clp protease is a major effector of RubisCO degradation in these conditions. Furthermore, we show that ClpP cannot be attenuated in the context of rbcL point mutations that prevent LSU folding. The mutant LSU remains in interaction with the chloroplast chaperonin complex. We propose that degradation of the mutant LSU by the Clp protease is necessary to prevent poisoning of the chaperonin. In the total absence of LSU, attenuation of ClpP leads to a dramatic stabilization of unassembled SSU, indicating that Clp is responsible for its degradation. In contrast, attenuation of ClpP in the absence of SSU does not lead to overaccumulation of LSU, whose translation is controlled by assembly. Altogether, these results point to RuBisCO degradation as one of the major house-keeping functions of the essential Clp protease. In addition, we show that non-assembled subunits of the ATP synthase are also stabilized when ClpP is attenuated. In the case of the atpA-FUD16 mutation, this can even allow the assembly of a small amount of CF1, which partially restores phototrophy.
Membrane-Based Clarification and Fractionation of Red Wine Lees Aqueous Extracts
Authors: Cassano Alfredo , Bentivenga Antonella , Conidi Carmela , Galiano Francesco , Saoncella Omar , Figoli Alberto
Published: June 2019

Polyvinylidenefluoride (PVDF) hollow fiber membranes prepared in laboratory through the inversion phase method were characterized and used to clarify an aqueous extract from red wine lees. Steady-state permeate fluxes of 53 kg/m2h were obtained in the treatment of the aqueous extract in selected operating conditions. Suspended solids were completely retained by the hollow fiber membranes while bioactive compounds, including polyphenols, anthocyanins, and resveratrol were recovered in the permeate stream. The clarified stream was then fractionated by nanofiltration (NF). Three different commercial membranes, in flat-sheet configuration (NP010 and NP030 from Microdyn-Nadir, MPF36 from Koch Membrane Systems), were selected and tested for their productivity and selectivity towards sugars and bioactive compounds, including phenolic compounds, anthocyanins, and resveratrol. All selected membranes showed high retention towards anthocyanins (higher than 93%). Therefore, they were considered suitable to concentrate anthocyanins from clarified wine lees extracts at low temperature. On the other hand, NF permeate streams resulted enriched in phenolic compounds and resveratrol. Among the selected membranes, the MPF36 exhibited the lowest retention towards resveratrol (10%) and polyphenols (26.3%) and the best separation factor between these compounds and anthocyanins.
Growth on Metallo-Supramolecular Coordination Polyelectrolyte (MEPE) Stimulates Osteogenic Differentiation of Human Osteosarcoma Cells (MG63) and Human Bone Marrow Derived Mesenchymal Stem Cells
Authors: Belka Janina , Nickel Joachim , Kurth Dirk G.
Published: June 2019

Background: Culturing of cells is typically performed on standard tissue culture plates generating growth conditions, which in general do not reflect the native three-dimensional cellular environment. Recent investigations provide insights in parameters, which strongly affect the general cellular behavior triggering essential processes such as cell differentiation. The physical properties of the used material, such as stiffness, roughness, or topology, as well as the chemical composition of the cell-surface interface are shown to play a key role in the initiation of particular cellular responses. Methods: We extended our previous research, which identified thin films of metallo-supramolecular coordination polyelectrolytes (MEPEs) as substrate to trigger the differentiation of muscular precursor cells. Results: Here, we show that the same MEPEs similarly stimulate the osteogenic differentiation of pre-osteoblasts. Remarkably, MEPE modified surfaces also trigger the differentiation of primary bone derived mesenchymal stem cells (BMSCs) towards the osteogenic lineage. Conclusion: This result leads to the conclusion that these surfaces individually support the specification of cell differentiation toward lineages that correspond to the natural commitment of the particular cell types. We, therefore, propose that Fe-MEPEs may be used as scaffold for the treatment of defects at least in muscular or bone tissue.
Effect of Cellulose Nanofibrils and TEMPO-mediated Oxidized Cellulose Nanofibrils on the Physical and Mechanical Properties of Poly(vinylidene fluoride)/Cellulose Nanofibril Composites
Authors: Barnes Eftihia , Jefcoat Jennifer A. , Alberts Erik M. , McKechnie Mason A. , Peel Hannah R. , Buchanan J. Paige , Weiss Jr. Charles A. , Klaus Kyle L. , Mimun L. Christopher , Warner Christopher M.
Published: June 2019

Cellulose nanofibrils (CNFs) are high aspect ratio, natural nanomaterials with high mechanical strength-to-weight ratio and promising reinforcing dopants in polymer nanocomposites. In this study, we used CNFs and oxidized CNFs (TOCNFs), prepared by a 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation process, as reinforcing agents in poly(vinylidene fluoride) (PVDF). Using high-shear mixing and doctor blade casting, we prepared free-standing composite films loaded with up to 5 wt % cellulose nanofibrils. For our processing conditions, all CNF/PVDF and TOCNF/PVDF films remain in the same crystalline phase as neat PVDF. In the as-prepared composites, the addition of CNFs on average increases crystallinity, whereas TOCNFs reduces it. Further, addition of CNFs and TOCNFs influences properties such as surface wettability, as well as thermal and mechanical behaviors of the composites. When compared to neat PVDF, the thermal stability of the composites is reduced. With regards to bulk mechanical properties, addition of CNFs or TOCNFs, generally reduces the tensile properties of the composites. However, a small increase (~18%) in the tensile modulus was observed for the 1 wt % TOCNF/PVDF composite. Surface mechanical properties, obtained from nanoindentation, show that the composites have enhanced performance. For the 5 wt % CNF/PVDF composite, the reduced modulus and hardness increased by ~52% and ~22%, whereas for the 3 wt % TOCNF/PVDF sample, the increase was ~23% and ~25% respectively.
Generation and Evaluation of LAI and FPAR Products from Himawari-8 Advanced Himawari Imager (AHI) Data
Authors: Chen Yepei , Sun Kaimin , Chen Chi , Bai Ting , Park Taejin , Wang Weile , Nemani Ramakrishna R. , Myneni Ranga B.
Published: June 2019

Leaf area index (LAI) and fraction of photosynthetically active radiation (FPAR) absorbed by vegetation are two of the essential biophysical variables used in most global models of climate, hydrology, biogeochemistry, and ecology. Most LAI/FPAR products are retrieved from non-geostationary satellite observations. Long revisit times and cloud/cloud shadow contamination lead to temporal and spatial gaps in such LAI/FPAR products. For more effective use in monitoring of vegetation phenology, climate change impacts, disaster trend etc., in a timely manner, it is critical to generate LAI/FPAR with less cloud/cloud shadow contamination and at higher temporal resolution—something that is feasible with geostationary satellite data. In this paper, we estimate the geostationary Himawari-8 Advanced Himawari Imager (AHI) LAI/FPAR fields by training artificial neural networks (ANNs) with Himawari-8 normalized difference vegetation index (NDVI) and moderate resolution imaging spectroradiometer (MODIS) LAI/FPAR products for each biome type. Daily cycles of the estimated AHI LAI/FPAR products indicate that these are stable at 10-min frequency during the day. Comprehensive evaluations were carried out for the different biome types at different spatial and temporal scales by utilizing the MODIS LAI/FPAR products and the available field measurements. These suggest that the generated Himawari-8 AHI LAI/FPAR fields were spatially and temporally consistent with the benchmark MODIS LAI/FPAR products. We also evaluated the AHI LAI/FPAR products for their potential to accurately monitor the vegetation phenology—the results show that AHI LAI/FPAR products closely match the phenological development captured by the MODIS products.
Learning the Orientation of a Loosely-Fixed Wearable IMU Relative to the Body Improves the Recognition Rate of Human Postures and Activities
Authors: Del Rosario Michael B. , Lovell Nigel H. , Redmond Stephen J.
Published: June 2019

Features were developed which accounted for the changing orientation of the inertial measurement unit (IMU) relative to the body, and demonstrably improved the performance of models for human activity recognition (HAR). The method is proficient at separating periods of standing and sedentary activity (i.e., sitting and/or lying) using only one IMU, even if it is arbitrarily oriented or subsequently re-oriented relative to the body; since the body is upright during walking, learning the IMU orientation during walking provides a reference orientation against which sitting and/or lying can be inferred. Thus, the two activities can be identified (irrespective of the cohort) by analyzing the magnitude of the angle of shortest rotation which would be required to bring the upright direction into coincidence with the average orientation from the most recent 2.5 s of IMU data. Models for HAR were trained using data obtained from a cohort of 37 older adults (83.9 ± 3.4 years) or 20 younger adults (21.9 ± 1.7 years). Test data were generated from the training data by virtually re-orienting the IMU so that it is representative of carrying the phone in five different orientations (relative to the thigh). The overall performance of the model for HAR was consistent whether the model was trained with the data from the younger cohort, and tested with the data from the older cohort after it had been virtually re-oriented (Cohen’s Kappa 95% confidence interval [0.782, 0.793]; total class sensitivity 95% confidence interval [84.9%, 85.6%]), or the reciprocal scenario in which the model was trained with the data from the older cohort, and tested with the data from the younger cohort after it had been virtually re-oriented (Cohen’s Kappa 95% confidence interval [0.765, 0.784]; total class sensitivity 95% confidence interval [82.3%, 83.7%]).
Structural Health Monitoring of Underground Structures in Reclamation Area Using Fiber Bragg Grating Sensors
Authors: Liu Zhen , Liu Pengzhen , Zhou Cuiying , Huang Yuncong , Zhang Lihai
Published: June 2019

The long-term structural performance of underground structures in reclamation areas is very sensitive to the vibrations caused by vehicles passing above the structures and environmental factors (e.g., tide levels, rainfall and temperature). In the present study, an integrated remote real-time structural health monitoring system using fiber Bragg grating sensors was developed to assess the structural performance of underground structures. Using a composite road box-type structure project in a reclamation area in Southern China as a case study, the developed real-time system was implemented to investigate the effects of changes in tide levels, rainfall, temperature and vehicle induced vibrations on crack propagation in the structure. The results show that the change in tide levels has little influence on the change in crack width in the structure, whereas variations in temperature could significantly influence the crack width with an average Pearson correlation of around 0.8. In addition, the crack width generally decreases with an increase in rainfall. Furthermore, a relatively low frequency (<25 Hz) induced by the traffic could result in a relatively larger crack width.
Investigation of a Signal Demodulation Method based on Wavelet Transformation for OFDR to Enhance Its Distributed Sensing Performance
Authors: Feng Kunpeng , Cui Jiwen , Dang Hong , Sun Xun , Jiang Dong , Jin Yihua , Niu Yizhao , Zhang Xuping
Published: June 2019

Optical fiber distributed sensing that is based on optical frequency domain reflectometer (OFDR) is a promising technology for achieving a highest spatial resolution downwards to several millimeters. An OFDR signal demodulation method that is based on Morlet wavelet transformation (WT) is demonstrated in detail to improve the resolution of distributed sensing physical quantity under a high spatial resolution, aiming at the trade-off between spatial and spectrum resolution. The spectrum resolution, spatial interval of the measured gauges, and spatial resolution can be manually controlled by adjusting the wavelet parameters. The experimental results that were achieved by the wavelet transformation (WT) method are compared with these by short time Fourier transformation (STFT) method and they indicate that significant improvements, such as strain resolution of 1 με, spatial resolution of 5 mm, average repeatability of 4.3 με, and stability of 7.3 με within one hour, have been achieved. The advantages of this method are high spatial and spectral resolution, robust, and applicability with current OFDR systems.
Research on the Frequency-Dependent Halfwave Voltage of a Multifunction Integrated Optical Chip in an Interferometric Fiber Optic Gyroscope
Authors: Bi Ran , Miao Lijun , Huang Tengchao , Ying Guangyao , Che Shuangliang , Shu Xiaowu
Published: June 2019

The multifunction integrated optical chip (MIOC) is one of the most critical parts of the interferometric fiber optic gyroscope (IFOG), and research on the halfwave voltage of the MIOC is meaningful for a high-precision IFOG. In this paper, the correlation between the frequency and halfwave voltage, which affects the interference light intensity of IFOG, is presented theoretically. A widespread measurement method for frequency dependence of the halfwave voltage, based on lock-in amplification and sinusoidal modulation, is proposed. Further, the measurement result and the oscillation of interference light intensity in the Sagnac interferometer are presented, which are in great agreement with the theory. This paper proposes the frequency dependence of the halfwave voltage and provides a new error research direction for the improvement of the MIOC in a high-precision IFOG.
A Simple and Label-Free Detection of As3+ using 3-nitro-L-tyrosine as an As3+-chelating Ligand
Authors: Park Jin-Ho , Yeom Gyuho , Hong Donggu , Jo Eun-Jung , Park Chin-Ju , Kim Min-Gon
Published: June 2019

A simple and rapid As3+ detection method using 3-nitro-L-tyrosine (N-Tyr) is reported. We discovered the specific property of N-Tyr, which specifically chelates As3+. The reaction between As3+ and N-Tyr induces a prompt color change to vivid yellow, concomitantly increasing the absorbance at 430 nm. The selectivity for As3+ is confirmed by competitive binding experiments with various metal ions (Hg2+, Pb2+, Cd2+, Cr3+, Mg2+, Ni2+, Cu2+, Fe2+, Ca2+, Zn2+, and Mn2+). Also, the N-Tyr binding site, binding affinity, and As3+/N-Tyr reaction stoichiometry are investigated. The specific reaction is utilized to design a sensor that enables the quantitative detection of As3+ in the 0.1–100 μM range with good linearity (R2 = 0.995). Furthermore, the method’s applicability for the analysis of real samples, e.g., tap and river water, is successfully confirmed, with good recoveries (94.32–109.15%) using As3+-spiked real water samples. We believe that our discovering and its application for As3+ analysis can be effectively utilized in environmental analyses such as those conducted in water management facilities, with simplicity, rapidity, and ease.
Picoliter Cuvette inside an Optical Fiber to Track Gold Nanoparticle Aggregation for Measurement of Biomolecules
Authors: Shiraishi Masahiko , Watanabe Kazuhiro , Kubodera Shoichi
Published: June 2019

This study demonstrated a measurement approach for biomolecules at the picoliter scale, using a newly developed picoliter cuvette inside an optical fiber constructed via near-ultraviolet femtosecond laser drilling. The sensing capacity was estimated to be within 0.4–1.2 pL due to an optical path length of 3–5 microns, as measured by scanning electron microscopy (SEM). The picoliter cuvette exhibited a change in the optical extinction spectrum after addition of biomolecules such as L-cysteine, in conjunction with a gold nanoparticle (GNP) dispersion solution, following a simple measurement configuration involving a small white light source and a compact spectrometer. A linear attenuation of the spectral dip near a wavelength of 520 nm was observed as the L-cysteine concentration was increased at 4 wt% of the GNP mass concentration. The measurement resolution of the concentration using the picoliter cuvette was evaluated at 0.125 mM. The experimental results showed the difference in aggregation processes caused by a different concentration of GNPs. Moreover, they revealed the ability of the picoliter cuvette to verify whether the concentration of GNPs in the liquid sample correspondingly determines homogeneous or inhomogeneous GNP aggregation, as supported by SEM observation and numerical calculations based on Mie theory.
Recent Progress on Electromagnetic Field Measurement Based on Optical Sensors
Authors: Peng Jun , Jia Shuhai , Bian Jiaming , Zhang Shuo , Liu Jianben , Zhou Xing
Published: June 2019

Electromagnetic field sensors are widely used in various areas. In recent years, great progress has been made in the optical sensing technique for electromagnetic field measurement, and varieties of corresponding sensors have been proposed. Types of magnetic field optical sensors were presented, including probes-based Faraday effect, magnetostrictive materials, and magnetic fluid. The sensing system-based Faraday effect is complex, and the sensors are mostly used in intensive magnetic field measurement. Magnetic field optical sensors based on magnetic fluid have high sensitivity compared to that based on magnetostrictive materials. Three types of electric field optical sensors are presented, including the sensor probes based on electric-optic crystal, piezoelectric materials, and electrostatic attraction. The majority of sensors are developed using the sensing scheme of combining the LiNbO3 crystal and optical fiber interferometer due to the good electro-optic properties of the crystal. The piezoelectric materials-based electric field sensors have simple structure and easy fabrication, but it is not suitable for weak electric field measurement. The sensing principle based on electrostatic attraction is less commonly-used sensing methods. This review aims at presenting the advances in optical sensing technology for electromagnetic field measurement, analyzing the principles of different types of sensors and discussing each advantage and disadvantage, as well as the future outlook on the performance improvement of sensors.
On the Prediction of Upwelling Events at the Colombian Caribbean Coasts from Modis-SST Imagery
Authors: Alonso del Rosario José J. , Vidal Pérez Juan M. , Blázquez Gómez Elizabeth
Published: June 2019

The upwelling cores on the Caribbean Colombian coasts are mainly located at the Peninsula de la Guajira and Cabo de la Aguja. We used monthly averaged Moderate Resolution Imaging Spectroradiometer (MODIS) sea surface temperature as the only information to build up a prediction model for the upwelling events. This comprised two steps: (i) the reduction of the complexity by means of the Karhunen–Loève transform and (ii) a prediction model of time series. Two prediction models were considered: (a) a parametric autoregressive-moving average (ARMA) time series from the Box–Jenkins methodology and (b) a harmonic synthesis model. The harmonic synthesis also comprised of two steps: the maximum entropy spectral analysis and a least-squares harmonic analysis on the set of frequencies. The parametric ARMA time series model failed at the time of prediction with a very narrow range, and it was quite difficult to apply. The harmonic synthesis allowed prediction with a horizon of six months with a correlation of about 0.80. The results can be summarized using the time series of the weights of the different oscillation modes, their spatial structures with the nodal lines, and a high confidence model with a horizon of prediction of about four months.
Real Time Estimation of the Pose of a Lower Limb Prosthesis from a Single Shank Mounted IMU
Authors: Duraffourg Clément , Bonnet Xavier , Dauriac Boris , Pillet Hélène
Published: June 2019

The command of a microprocessor-controlled lower limb prosthesis classically relies on the gait mode recognition. Real time computation of the pose of the prosthesis (i.e., attitude and trajectory) is useful for the correct identification of these modes. In this paper, we present and evaluate an algorithm for the computation of the pose of a lower limb prosthesis, under the constraints of real time applications and limited computing resources. This algorithm uses a nonlinear complementary filter with a variable gain to estimate the attitude of the shank. The trajectory is then computed from the double integration of the accelerometer data corrected from the kinematics of a model of inverted pendulum rolling on a curved arc foot. The results of the proposed algorithm are evaluated against the optoelectronic measurements of walking trials of three people with transfemoral amputation. The root mean square error (RMSE) of the estimated attitude is around 3°, close to the Kalman-based algorithm results reported in similar conditions. The real time correction of the integration of the inertial measurement unit (IMU) acceleration decreases the trajectory error by a factor of 2.5 compared to its direct integration which will result in an improvement of the gait mode recognition.
The Development of Loyalty to Earthen Defensive Heritage as a Key Factor in Sustainable Preventive Conservation
Authors: Prados-Peña M. Belén , Gutiérrez-Carrillo M. Lourdes , Del Barrio-García Salvador
Published: June 2019

One of the main risks to the preservation of Spanish defensive heritage is anthropic in origin and is associated with local society’s lack of cultural identification with these cultural assets. Consequently, there is a dearth of conservation strategies. In this paper, the current situation is examined, then a management model is proposed, with the Torre de Romilla in the Granada province (Spain) as its focus. The model is constructed on the basis of research regarding the antecedents to loyalty towards this heritage landmark, in order to enhance its value. To accomplish this, survey data from 200 randomly selected subjects was collected and analysed. The results indicate that the antecedent factors which determine loyalty are place attachment and its perceived image, which lead to an increased probability that the site will be visited and recommended. The direct consequence of this is that contributions to the economy from tourism would allow for the sustainable conservation of these assets.
Can Agroforestry Grow beyond Its Niche and Contribute to a Transition towards Sustainable Agriculture in Sweden?
Authors: Schaffer Christina , Eksvärd Karin , Björklund Johanna
Published: June 2019

Agroforestry is thought to be an approach that could support agriculture in the transition from a system with sustainability problems to one containing regenerative activities contributing to viable ecosystems and, therefore, sustainability solutions. A transdisciplinary and participatory action research (PAR) group that included farmers approached the development of temperate agroforestry systems in the modern agricultural setting of Sweden through practical experience on 12 farms for collective analysis. The objective was to research potential systems such as edible forest gardens, silvopasture and silvoarable systems to discuss their use and effects as well as scaling possibilities. Knowledge and experiences of challenges and solutions related to the development of agroforestry were identified at both niche and regime levels.
Extracting Spatial Patterns of Intercity Tourist Movements from Online Travel Blogs
Authors: Gao Yong , Ye Chao , Zhong Xiang , Wu Lun , Liu Yu
Published: June 2019

Spatial patterns of tourist mobility are important for tourism management and planning. A large number of traveler-generated content accumulated on the internet provide a unique opportunity for revealing comprehensive spatial patterns of tourist movements. Instead of concentrating on a single city or attraction in previous research, this work investigates the intercity travel flows extracted from the online travel blogs in China from 2012 to 2016. The descriptive statistics of travel flows are first analyzed. The distribution of travel volume is found to satisfy the power-law distribution. Based on the intercity travel flows, a network structure is then constructed to investigate tourism interactions between cities. After four communities and 14 sub-communities being detected from the network, a tourism spatial layout with regional agglomeration effects are recognized. This research concludes that distance is essential in determining tourist movements based on a spatial interaction model. Intercity travel flows decline with distance under a power-law function. These results reveal the spatial patterns of tourist movements at an intercity scale. It will be helpful for arranging tourism resources, predicting tourist flows, and maintaining sustainable tourism.
A Transit Route Network Design Problem Considering Equity
Authors: Kim Myeonghyeon , Kho Seung-Young , Kim Dong-Kyu
Published: June 2019

As concerns about environmental quality, social equity, and economic efficiency are increasing, efforts on improving the sustainability of public transportation are being made all over the world. This study aims to propose a transit route network design problem that considers modal and spatial equities. The equities are accommodated by using two indexes that can simultaneously reflect mobility and accessibility. A decision-making process for designing a transit route network consists of the selection of the target line, selection of the target node, the determination of an alternative line, and the implementation of a procedure for setting frequency. The model is configured through bi-level modeling based on an iterative process to calculate the modal split and the traffic and transit assignments with changes in the transit route network. While the frequency of each line is determined by a genetic algorithm in the upper model, the modal split and traffic and transit assignments are implemented in the lower model. This transit route network design model and the associated algorithms are applied to a sample network. As a result, an improved solution with equity and the lower total cost is identified based on a comparison with the existing transit route network.
Approach Methodology for Comprehensive Assessing the Public Passenger Transport Timetable Performances at a Regional Scale
Authors: Ľupták Vladimír , Droździel Paweł , Stopka Ondrej , Stopková Mária , Rybicka Iwona
Published: June 2019

The paper is focused on the issue of assessing the quality of transport connectivity on a predesignated transport network in regular public passenger transport at a regional scale. Comprehensively, using the defined key qualitative indicators, it assesses the performance of passenger transport timetables, in both ways of ex ante, as well as ex post. Existing methodologies in a given issue have only dealt with a partial assessment of the transport connectivity quality on specific transport network. However, unlike them, the objective of this manuscript was to propose a new unified methodology to assess the passenger transport timetables in terms of transport connectivity, and subsequently to complexly evaluate the whole predesignated regional transport network from a qualitative point of view. In this paper, the proposed methodology is demonstrated on a particular regional transport network, specifically an existing railway network in the Slovak Republic, whereby the data related to regional passenger transport timetables for a certain day is an input factor. The purpose of this study was to design and verify a draft methodological procedure to assess the quality of transport connectivity on a certain transport network, thus moving towards more effective evaluation of integrated transport systems. Its practical applicability consists in comparison of existing and proposed timetables, which is considered one of the crucial factors in terms of public passenger transport quality.
The Evaluation of the Project School Model in Terms of Organizational Sustainability and Its Effect on Teachers’ Organizational Commitment
Authors: Koç Ahmet , Bastas Mert
Published: June 2019

The Turkish Ministry of National Education has been implementing a new management model in the Turkish educational system. The structural features of state-run project schools are being developed with various innovations in terms of management and education models. Specifically, the new management model in which school principals share the authority to make their own teams is of great importance to researchers, educational policy makers, and executors. This study aims to designate the effects of project schools’ structural and managerial characteristics on teachers’ organizational commitment and the schools’ organizational sustainability. It was designed using a sequential mixed research method including scaling and interviewing techniques. In addition, the teachers’ organizational commitment levels in project schools, which were designated as the experimental group, are compared with the teachers’ organizational commitment levels in non-project schools, which were selected as the control group. The study, conducted in 2018–2019, is comprised of 15 project schools and 9 non-project schools located in Istanbul and involved 603 teachers working in these schools. The results show that the structural and managerial features of project schools have positive effects on teachers’ organizational commitment and that this school model seems sustainable, based on all the positive points gathered.
Research of the Equipment Self-Calibration Methods for Different Shape Fertilizers Particles Distribution by Size Using Image Processing Measurement Method
Authors: Laucka Andrius , Adaskeviciute Vaida , Andriukaitis Darius
Published: June 2019

The fourth digital revolution of industry makes substantive changes to the rate and methodology of work performance. Machines and robots do the majority of work in robotized and automated factories, while people only supervise them. After an increase of production efficiency, quality control became a critical point. Therefore, quality control systems of computer visions are increasingly installed. The branch of chemical industry requires measurements of quality at as great a frequency as possible. Consequently, indirect measurements are effectively used at this point. This research presents the method of indirect particle measurement. Particles are measured using digital image processing. The algorithm is used for particle measurement to automatically adjust the measurement results. Numerical intelligence is added to the algorithm to increase the accuracy of correction results. The research deals with the problem of matching the results of indirect measurements and the results of the control equipment. For data analysis, fertilizer diameter, mean diameter, aspect ratio, symmetry, sphericity, convexity and some other parameters are used. The mismatch of the artificial neural network results with the control equipment results is slightly higher than 1%.
Internet of Energy Training through Remote Laboratory Demonstrator
Authors: Assante Dario , Capasso Clemente , Veneri Ottorino
Published: June 2019

In this paper, a new learning tool is proposed to train professional figures, such as entrepreneurs, engineers, and technicians, who need to improve their skills in the field of Internet of Energy. The proposed tool aims to cover the lack of experimental knowledge on new energy systems and to layer proper skills, which are useful to deal with challenges required by smart energy management in the new complex distributed configuration of the electric power systems, characterized by demand response services. This tool is based on a small-scale laboratory demonstrator, representative of a smart rural house, equipped with a measurement and control system. This demonstrator can be remotely accessed, through web server applications based on a low cost single-board computer. Trainers can have direct experience on the main concepts related to smart grids, renewable energy sources, electrochemical storage systems, and electric vehicles, through the use of the proposed tool managed by the web software interface.
From Discovery of Snake Venom Disintegrins to A Safer Therapeutic Antithrombotic Agent
Authors: Kuo Yu-Ju , Chung Ching-Hu , Huang Tur-Fu
Published: June 2019

Snake venoms affect blood coagulation and platelet function in diverse ways. Some venom components inhibit platelet function, while other components induce platelet aggregation. Among the platelet aggregation inhibitors, disintegrins have been recognized as unique and potentially valuable tools for examining cell–matrix and cell–cell interactions and for the development of antithrombotic and antiangiogenic agents according to their anti-adhesive and anti-migration effect on tumor cells and antiangiogenesis activities. Disintegrins represent a family of low molecular weight, cysteine-rich, Arg-Gly-Asp(RGD)/Lys-Gly-Asp(KGD)-containing polypeptides, which inhibit fibrinogen binding to integrin αIIbβ3 (i.e., platelet glycoprotein IIb/IIIa), as well as ligand binding to integrins αvβ3, and α5β1 expressed on cells (i.e., fibroblasts, tumor cells, and endothelial cells). This review focuses on the current efforts attained from studies using disintegrins as a tool in the field of arterial thrombosis, angiogenesis, inflammation, and tumor metastasis, and briefly describes their potential therapeutic applications and side effects in integrin-related diseases. Additionally, novel R(K)GD-containing disintegrin TMV-7 mutants are being designed as safer antithrombotics without causing thrombocytopenia and bleeding.
Evolution and Interspecies Transmission of Canine Distemper Virus—An Outlook of the Diverse Evolutionary Landscapes of a Multi-Host Virus
Authors: Duque-Valencia July , Sarute Nicolás , Olarte-Castillo Ximena A. , Ruíz-Sáenz Julián
Published: June 2019

Canine distemper virus (CDV) is a worldwide distributed virus which belongs to the genus Morbillivirus within the Paramyxoviridae family. CDV spreads through the lymphatic, epithelial, and nervous systems of domestic dogs and wildlife, in at least six orders and over 20 families of mammals. Due to the high morbidity and mortality rates and broad host range, understanding the epidemiology of CDV is not only important for its control in domestic animals, but also for the development of reliable wildlife conservation strategies. The present review aims to give an outlook of the multiple evolutionary landscapes and factors involved in the transmission of CDV by including epidemiological data from multiple species in urban, wild and peri-urban settings, not only in domestic animal populations but at the wildlife interface. It is clear that different epidemiological scenarios can lead to the presence of CDV in wildlife even in the absence of infection in domestic populations, highlighting the role of CDV in different domestic or wild species without clinical signs of disease mainly acting as reservoirs (peridomestic and mesocarnivores) that are often found in peridomestic habits triggering CDV epidemics. Another scenario is driven by mutations, which generate genetic variation on which random drift and natural selection can act, shaping the genetic structure of CDV populations leading to some fitness compensations between hosts and driving the evolution of specialist and generalist traits in CDV populations. In this scenario, the highly variable protein hemagglutinin (H) determines the cellular and host tropism by binding to signaling lymphocytic activation molecule (SLAM) and nectin-4 receptors of the host; however, the multiple evolutionary events that may have facilitated CDV adaptation to different hosts must be evaluated by complete genome sequencing. This review is focused on the study of CDV interspecies transmission by examining molecular and epidemiological reports based on sequences of the hemagglutinin gene and the growing body of studies of the complete genome; emphasizing the importance of long-term multidisciplinary research that tracks CDV in the presence or absence of clinical signs in wild species, and helping to implement strategies to mitigate the infection. Integrated research incorporating the experience of wildlife managers, behavioral and conservation biologists, veterinarians, virologists, and immunologists (among other scientific areas) and the inclusion of several wild and domestic species is essential for understanding the intricate epidemiological dynamics of CDV in its multiple host infections.
Two Phages of the Genera Felixunavirus Subjected to 12 Hour Challenge on Salmonella Infantis Showed Distinct Genotypic and Phenotypic Changes
Authors: Rivera Dácil , Hudson Lauren K. , Denes Thomas G. , Hamilton-West Christopher , Pezoa David , Moreno-Switt Andrea I.
Published: June 2019

Salmonella Infantis is considered in recent years an emerging Salmonella serovar, as it has been associated with several outbreaks and multidrug resistance phenotypes. Phages appear as a possible alternative strategy to control Salmonella Infantis (SI). The aims of this work were to characterize two phages of the Felixounavirus genus, isolated using the same strain of SI, and to expose them to interact in challenge assays to identify genetic and phenotypic changes generated from these interactions. These two phages have a shared nucleotide identity of 97% and are differentiated by their host range: one phage has a wide host range (lysing 14 serovars), and the other has a narrow host range (lysing 6 serovars). During the 12 h challenge we compared: (1) optical density of SI, (2) proportion of SI survivors from phage-infected cultures, and (3) phage titer. Isolates obtained through the assays were evaluated by efficiency of plating (EOP) and by host-range characterization. Genomic modifications were characterized by evaluation of single nucleotide polymorphisms (SNPs). The optical density (600 nm) of phage-infected SI decreased, as compared to the uninfected control, by an average of 0.7 for SI infected with the wide-host-range (WHR) phage and by 0.3 for SI infected with the narrow-host-range (NHR) phage. WHR phage reached higher phage titer (7 × 1011 PFU/mL), and a lower proportion of SI survivor was obtained from the challenge assay. In SI that interacted with phages, we identified SNPs in two genes (rfaK and rfaB), which are both involved in lipopolysaccharide (LPS) polymerization. Therefore, mutations that could impact potential phage receptors on the host surface were selected by lytic phage exposure. This work demonstrates that the interaction of Salmonella phages (WHR and NHR) with SI for 12 h in vitro leads to emergence of new phenotypic and genotypic traits in both phage and host. This information is crucial for the rational design of phage-based control strategies.
Textile Wastewater Purification Using an Elaborated Biosorbent Hybrid Material (Luffa–Cylindrica–Zinc Oxide) Assisted by Alternating Current
Authors: Othmani Amina , Kesraoui Aida , Boada Roberto , Seffen Mongi , Valiente Manuel
Published: June 2019

This paper aims to synthesize hybrid materials with high pollutant-uptake capacity and low costbased based on Luffa cylindrica (L.C) and different percentage of Zn2+ in the presence and absence of alternating current (AC). Physico-chemical, morphological and structural characterizations of the hybrid materials were performed by Boehm method, point zero charge (pHpzc), infrared characterizations (IR), scanning electron microscopy (SEM), energy–dispersive spectroscopyand and X-ray photoelectron spectroscopy. The efficiency of the designed hybrid materials was optimized based on their performance in water depollution. Methylene blue (MB) and industrial textile wastewater were the investigated pollutants models. IR characterizations confirmed the fixation of Zn2+ onto the L.C by the creation of Zn-OH, Zn-O and Zn-O-C bonds. Boehm titration showed that the fixation of Zn2+ onto L.C is accompanied by an increase of the basic functions of its surface and subsequently an increase in the pHpzc. SEM results confirmed the fixation of Zn2+ onto the L.C coupling AC with biosorption showed an increase in the adsorbed amount of MB and speed when adding the 4% of Zn2+ compared to the pure L.C the Qm shifted from 3.22 to 9.84 and 8.81 mg/g, respectively, for hybrid materials synthesized under AC, in absence of AC and pure L.C.