bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysing Participation in Electronic Networks of Practice (Preprint)
Authors: Charkhsaz Fatemeh , Warnier Martijn , Isaai Mohammad Taghi , Brazier Frances , Dayani Malihe
Published: May 2020

BACKGROUND

Electronic Networks of Practice (ENoP) are professional social networks in which professionals share knowledge, advice, and ideas with each other on challenges encountered in practice. Although different aspects of their use have been studied in the past ranging from the motivation of participants to the structure of emerging networks, very little is known about how professionals participate in ENoPs.

OBJECTIVE

This study proposes a comprehensive and detailed exploratory, conversation-based data analysis methodology to analyse closed, informal, and message-based ENoP participation, and also shows how this methodology can be used to study, develop, and maintain a well-connected and active ENoP.

METHODS

The proposed methodology includes a number of data analysis methods such as data clustering, social network analysis, Principal Component Analysis (PCA), correlation analysis, content analysis, and conversation analysis. It is applied to a case study for an ENoP in breast cancer treatment for which participation is analysed and guidelines formulated.

RESULTS

The results show how the methodology can be applied to analyse informal and messages-based ENoP participation including a specific conversation extraction method, a specific social network elements extraction method, and a set of macro and micro measures with which to determine participation. Applying the proposed methodology to a case of an ENoP in breast cancer treatment results in a dataset of 51 extracted conversations in 1000 messages between 100 specialists in breast cancer treatment. The results show the network participation is higher when an active, central and well-known specialist starts a conversation; when feedback is acknowledged; when an initiator or other active, central and well-known specialists are involved in a conversation; and when a conversation does not overlap with another active and ongoing conversation. As another result, 5 dimensions and 5 clusters of conversations are defined and how they relate to ENoP participation.

CONCLUSIONS

The findings inform the research literature in five ways: (i) how to analyse informal and messages-based ENoP participation; (ii) the role members of ENoP, in particular, central members and admins play to keep a conversation alive; (iii) the way in which professionals engage in conversations; (iv) triggers for more active, engaging, continued user participation; (v) dimensions and attributes of conversations in ENoP and how they relate to ENoP participation. The methodology and guidelines together provide ENoP researchers, developers, admins, and expert members a means with which to study, develop, and maintain a well-connected and active ENoP.
ColistinDose, a Mobile App for Determining Intravenous Dosage Regimens of Colistimethate in Critically Ill Adult Patients: Clinician-Centered Design and Development Study (Preprint)
Authors: Hua Xueliang , Li Chen , Pogue Jason M , Sharma Varun S , Karaiskos Ilias , Kaye Keith S , Tsuji Brian T , Bergen Phillip J , Zhu Yan , Song Jiangning , Li Jian
Published: May 2020

BACKGROUND

Determining a suitable dose of intravenous colistimethate is challenging because of complicated pharmacokinetics, confusing terminology, and the potential for renal toxicity. Only recently have reliable pharmacokinetic/pharmacodynamic data and dosing recommendations for intravenous colistimethate become available.

OBJECTIVE

The aim of this work was to develop a clinician-friendly, easy-to-use mobile app incorporating up-to-date dosing recommendations for intravenous colistimethate in critically ill adult patients.

METHODS

Swift programming language and common libraries were used for the development of an app, ColistinDose, on the iPhone operating system (iOS; Apple Inc). The compatibility among different iOS versions and mobile devices was validated. Dosing calculations were based on equations developed in our recent population pharmacokinetic study. Recommended doses generated by the app were validated by comparison against doses calculated manually using the appropriate equations.

RESULTS

ColistinDose provides 3 major functionalities, namely (1) calculation of a loading dose, (2) calculation of a daily dose based on the renal function of the patient (including differing types of renal replacement therapies), and (3) retrieval of historical calculation results. It is freely available at the Apple App Store for iOS (version 9 and above). Calculated doses accurately reflected doses recommended in patients with varying degrees of renal function based on the published equations. ColistinDose performs calculations on a local mobile device (iPhone or iPad) without the need for an internet connection.

CONCLUSIONS

With its user-friendly interface, ColistinDose provides an accurate and easy-to-use tool for clinicians to calculate dosage regimens of intravenous colistimethate in critically ill patients with varying degrees of renal function. It has significant potential to avoid the prescribing errors and patient safety issues that currently confound the clinical use of colistimethate, thereby optimizing patient treatment.
Defining Digital Game-Based Learning for Science, Technology, Engineering, and Mathematics: A New Perspective on Design and Developmental Research (Preprint)
Authors: Ishak Shahrul Affendi , Din Rosseni , Hasran Umi Azmah
Published: May 2020

UNSTRUCTURED

In the modern age, digital games are widely used as informal media for Science, Technology, Engineering, and Mathematics (STEM) education and medical therapy for game-based learning. Digital games provide learners with a graphical system of interaction that enhances scientific concepts within an enjoyable environment. The vastly increasing number of digital games produced in the market affects the quality of STEM digital games while requiring multidisciplinary expertise. This paper proposes a framework for STEM digital game-based learning encompassing input-process-output stages. Several studies from the early 2000s onward were reviewed to discuss and present a new perspective on a framework for the design and development of digital games, particularly for STEM. This proposed framework consists of digital game development as input, experience as a process, and constructs as output. This simple and precise framework will generate a universal product for various types of learners. It can thus be used as a guideline for game designers, developers, and experts to develop STEM digital games and achieve better learning outcomes.
Factors Associated With Influential Health-Promoting Messages on Social Media: Content Analysis of Sina Weibo (Preprint)
Authors: Rao Qingmao , Zhang Zuyue , Lv Yalan , Zhao Yong , Bai Li , Hou Xiaorong
Published: May 2020

BACKGROUND

Social media is a powerful tool for the dissemination of health messages. However, few studies have focused on the factors that improve the influence of health messages on social media.

OBJECTIVE

To explore the influence of goal-framing effects, information organizing, and the use of pictures or videos in health-promoting messages, we conducted a case study of Sina Weibo, a popular social media platform in China.

METHODS

Literature review and expert discussion were used to determine the health themes of childhood obesity, smoking, and cancer. Web crawler technology was employed to capture data on health-promoting messages. We used the number of retweets, comments, and likes to evaluate the influence of a message. Statistical analysis was then conducted after manual coding. Specifically, binary logistic regression was used for the data analyses.

RESULTS

We crawled 20,799 Sina Weibo messages and selected 389 health-promoting messages for this study. Results indicated that the use of gain-framed messages could improve the influence of messages regarding childhood obesity (P<.001), smoking (P=.03), and cancer (P<.001). Statistical expressions could improve the influence of messages about childhood obesity (P=.02), smoking (P=.002), and cancer (P<.001). However, the use of videos significantly improved the influence of health-promoting messages only for the smoking-related messages (P=.009).

CONCLUSIONS

The findings suggested that gain-framed messages and statistical expressions can be successful strategies to improve the influence of messages. Moreover, appropriate pictures and videos should be added as much as possible when generating health-promoting messages.
Knowledge and Psychological Stress Related to COVID-19 Among Nursing Staff in a Hospital in China: Cross-Sectional Survey Study (Preprint)
Authors: Huang Huaping , Zhao Wen-Jun , Li Gui-Rong
Published: May 2020

BACKGROUND

Since December 2019, coronavirus disease (COVID-19) has been rapidly spreading worldwide. Nurses play a key role in fighting this disease and are at risk of COVID-19 infection. Therefore, there is an urgent need to assess the mental health condition of nurses and establish appropriate interventions to reduce the negative psychiatric outcomes of the pandemic.

OBJECTIVE

The objectives of this study were to evaluate the knowledge and psychological stress related to COVID-19 among nursing staff and to provide evidence of the need for targeted training and psychological intervention.

METHODS

This cross-sectional web-based survey study was performed in a class 3 grade A general hospital in a southwest province of China from March 1 to March 15, 2020. A self-designed questionnaire with questions about COVID-19–related prevention and control knowledge and the Triage Assessment Form (TAF) were used to assess nursing staff’s knowledge of COVID-19 and their degree of psychological stress, respectively. SPSS 23.0 was applied for statistical analysis of the collected data.

RESULTS

A total of 979 nurses completed the questionnaire. The results showed that the nursing staff provided the fewest correct answers to questions about continuous viral nucleic acid testing specifications (379/979 correct answers, 38.7%), isolation/discharge criteria (539/979 correct answers, 55.1%), and management measures for patients with suspected symptoms (713/979 correct answers, 72.8%). The median total score of the TAF was 7.0 (IQR 5.0-12.0), and there were statistically significant differences in scores between different nursing roles, years of work experience, and hospital departments (P<.05).

CONCLUSIONS

This study indicated that nursing staff have insufficient knowledge about COVID-19. Meanwhile, although the psychological damage to nurses during the pandemic was found to be low, nurse managers must continue to monitor the mental health of nursing staff and perform timely interventions.
MOTOR SKILLS OF SOCCER PLAYERS AGED 16-18 IN REGARD TO COMPETITION LEVEL AND PLAYING POSITION
Authors: Momčilović Zoran , Marković Srđan , Bogavac Dragana , Milosavljević Đukić Tatjana , Bugarski Srđan
Published: May 2020

TThe aim of this paper was to examine the differences in the motor skills of soccer players aged 16-18 years who play in different competition levels (National League and Regional League), as well as players who play in different positions in the team. The standard testing battery for the motor skills assessment of soccer players was used to evaluate the motor skills. As for the evaluation of the differences between the different playing positions, a two-factor ANOVA with the factor Competition Level (National and Regional Level) and the factor Position (forward, midfielder, side defender, central defender) was used. A two-factor ANOVA with the factor Competition Level (National and Regional Level) and the factor Age (16, 17 and 18 years of age) was used to evaluate the differences between the different quality levels. The study included 126 male soccer players 16 to 18 years of age (N16=45, N17=41, N18=40) divided into 4 positions on the team: forwards (N=37, BH=179.2±5.0, BM=70.1±6.6), midfielders (N=48, BH=177.9±6.3, BM=69.6±7.9), side defenders (N=22, BH=176.6±5.4, BM=67.5±5.7) and central defenders (N=19, BH=184.0±4.3, BM=72.3±6.6). Because of significantly different activities in the field, the goalkeeper position was excluded from this study. The results indicate that motor skills do not differentiate players of different competition levels, and that there is a gap between players aged 18 years in aerobic endurance which is the basis of success in soccer.  Also, the obtained results suggest that motor skills could differentiate players at certain positions. However, it was specifically found that only alactic capabilities type of speed and agility, differentiate forwards from other positions, especially from midfielders.
PRAGMATIC ASPECTS OF ACADEMIC WRITING IN HEALTH CARE
Authors: Kerničan Leontina , Stojković Nadežda
Published: May 2020

A clear delineation is obvious to understand specific aspects regarding the use of academic writing in health care. Thus, more pragmatic and less general aspects of academic writing for medical purposes will be taken into account. Due to solid experience in students’ education of LSP at medical faculties, we are delighted to share our academic experience primarily with students as well as with our colleagues. The paper will be focused on emphasizing the critical points of structuring medical texts. Namely, it will present the path of text structuring to help readers understand the specific aspects of high relevance for medical authors. Also, it will draw attention to the role of health care practitioners as well as how they should evaluate this aspect in their professional communication. Furthermore, we would like to pay attention to approaching fundamental problems in academic writing in health care.
La percepción de inseguridad: miedo a la victimización en la zona del Valle de México
Authors: Olvera-Aldana Fabiola , Martínez-Martínez Oscar
Published: May 2020

Se examina la relación entre el miedo a la victimización y la victimización vicaria en la percepción de inseguridad en la Zona del Valle de México. Con los datos recolectados a partir de 64 entrevistas a profundidad, se buscó explorar si el miedo a ser víctima de un delito o saber que otras personas han sido vulneradas, se relaciona con la percepción de inseguridad. De manera general, se identificó que las personas en la Ciudad de México y el Estado de México expresaron en su discurso en el que las percepciones de inseguridad fueron similares, sobre todo en aquellos casos en los que fueron victimizados en una o varias ocasiones. En cuanto a la victimización vicaria, se encontraron diferentes entre ambos lugares, siendo la percepción y el miedo a la victimización vicaria mayor en el Estado de México. En ambos casos, se identificó que el impacto derivado de la percepción de inseguridad se presenta mayormente en cambios conductuales para prevenir la victimización y esto a su vez mermó en la calidad de vida de los y las participantes.
Adquisición de la función instruccional como efecto de la especificidad y el contenido de las descripciones
Authors: Cuevas-Lopez Paula Cecilia , Ortiz-Rueda Gerardo Alfonso , Serrador-Diez Concepción , Rodríguez-Pérez María Elena
Published: May 2020

Se ha sugerido que la función de una instrucción es restringir el rango de respuestas del individuo y, así, evitar que este responda incorrectamente. La adquisición de esta función instruccional está relacionada con variables tales como el tipo de la descripción, la correspondencia entre la descripción y la contingencia que describe, así como la frecuencia de retroalimentación. En el presente estudio se exploró una variable que no ha sido explorada sistemáticamente, el contenido de la descripción (en términos de instancia, modalidad, relación y dimensión). En un experimento con dieciséis estudiantes universitarios se evaluaron los efectos del contenido de descripciones Genéricas-Pertinentes utilizando retroalimentación intermitente en una tarea de igualación de la muestra de primer orden. Los resultados muestran bajos porcentajes de aciertos para los grupos con descripciones en términos de instancia, modalidad y relación, y altos niveles de aciertos para los participantes del grupo con contenido de la descripción en términos de dimensión. Se discute en términos de las propiedades de la contingencia que son enfatizadas en las descripciones y cómo estas descripciones promueven desempeños diferenciales.
Modulatory Effects of Honey on Gastric Acidity and Plasma Postprandial Bicarbonate in Wistar Rats
Authors: Apugo Uchechukwu Ifeanyichukwu , Obia Onyebuchi
Published: May 2020

Introduction: Honey is a naturally occurring sweet substance of plant origin composed mainly of fructose, glucose, water, antioxidants and other constituents. Its enormous constituents confer it with medicinal and nutritive usefulness.

Objectives: To assess the modulatory effects of honey on gastric acidity and plasma postprandial bicarbonate in wistar rats.

Method: A total of 24 male wistar rats weighing 200-250g were divided into four groups of six rats each; Group I served as control, Group II received 50% Honey (10ml/kg), Group III received omeprazole (20mg/kg) and Group IV received a combination of Omeprazole and Honey. The pH of gastric effluents in each rat was measured 15, 30 and 45mins using a pH meter after administration of the respective substances in each group.

Result and Discussion: Both honey and omeprazole respectively caused significant increases in the pH of gastric effluents, however, while that of honey was slow and steady, that of omeprazole was sharp and sustained. The 45-min pH level of omeprazole group was significantly higher than that of honey group. The combined group showed an initial sharp rise similar to omeprazole alone but gradually declined in the succeeding time interval. A combination of omeprazole and honey resulted in 27% reduction in the postprandial serum bicarbonate whereas omeprazole alone caused 41% reduction

Conclusion: The present study concludes that honey modulated gastric pH to levels possibly favourable to gastric function by either a direct action of reducing gastric acidity or acting as an antacid or both. Honey therefore could be described as a buffer in omeprazole stimulated gastric acid inhibition and a potential antacid.

Keywords: Honey, Gastric acidity, Gastric pH, bicarbonate.
Formulation and Evaluation of Protein Bound Paclitaxel Nanoparticles for Injectable Suspension
Authors: Jain Surendra Kumar , Thakur Suchi , Jain Ruchi , Jain Nilesh
Published: May 2020

Aims: The aim of present study is to develop Paclitaxel nanoparticles for injectable suspension, an anti-neoplastic drug formulation.

Study design:  Mention the design of the study here.

Place and Duration of Study: Sagar Institute of Research & Technology- Pharmacy, Ayodhya Bypass Road, Bhopal, between June 2017 and June2018.

Methodology: The Human serum albumin (HSA) is the most abundant plasma protein in the human blood with a half-life of 19 days. It can reversibly bind hydrophobic drug substances, transport them in the body and release drugs at cell surface. The formulation is prepared by homogenization at high-pressure of paclitaxel in the presence of human serum albumin into a nanoparticle colloidal suspension. Paclitaxel nano particles have been stabilized by human albumin and maintain the average size of 100 nm

Results: The particle size of the reconstituted solution is checked using the laser diffraction Technique the particle is White to yellow lyophilized after reconstitution the particle become homogeneous milky suspension without visible particulates. Reconstitution time NMT 25 minutes 20.45 sec. The assay was performed by HPLC and found to be 90.0% to 110.0% of label. The retention time of Paclitaxel peak obtained in sample corresponds to the respective standards obtained from standards the pH NLT 6.00 to NMT 8.00 Particle size NLT 100 nm – NMT 200 nm. Sterility test was comply as per USP <71>

Conclusion: The nano-delivery systems could have the potential to be free of Cremophor EL and ethanol, enhance Paclitaxel solubility, improve Paclitaxel pharmacokinetic profiles in vivo, decrease its side effects, passively or actively target to tumor sites due to the EPR (Enhanced Permeability and Retention) effect and the use of targeting ligands, respectively, nanotechnology is a very active research area in both academic and industrial settings.

Keywords: paclitaxel, Anti-cancer, nanotechnology, Injectable, Suspension
Phytochemical, HPLC and FTIR Analysis of Methanolic Extract from Gracilaria dura (C Agardh) J Agardh.
Authors: Sumayya S S , Lubaina A S , Murugan K
Published: May 2020

Marine algae are known to contain a wide variety of bioactive compounds. They are also rich in novel biomolecules and can be explored for the development of drugs to combat lifestyle diseases like cancer, diabetes etc. Red algae are known for their nutraceutical and functional importance. But there are a lot of limitations regarding their availability and in estimating which algal fractions are biologically active. Similarly, the mode of digestion of such compounds in human body is not yet properly traced. In this juncture, the present study was aimed to evaluate the phytochemical screening of the methanolic extract of the red alga, Gracilaria dura. Methanolic extract of G. dura showed the presence of reducing sugar, flavonoids, glycosides, tannins and terpenoids. Further, the HPLC analysis was attempted to fractionate the polyphenolics. Various phenolic acids such as of gallic acid, vanillic acid, sinapic acid, p-coumaric acid, hydroxybenzoic, phloroglucinol, catechol and cinnamic acid were identified. Subsequently, the methanolic solvent extract of G. dura was subjected to fourier transform infrared spectroscopy for the analysis of the functional groups. The results based on the spectral data of FTIR revealed the presence of aliphatic constituents containing alkanes, ketones, alkyl halides, hydroxyl groups etc. Thus, the observed finding envisages that methanolic extract of G. dura contained potential bioactive compounds which can be used for analysing the various biological activities.

Keywords: Gracilaria dura, Phytochemical, Methanolic extract, HPLC, FTIR
Preventive and Curative Effects of Atriplex Halimus L. Aqueous Extract on Benzene Provoked Hepatic Injury in Rats
Authors: Khaoula Zeghib , Ali Boutlelis Djahra
Published: May 2020

Objective: The present study was designed to estimate the preventive and curative potency of aqueous extract of Atriplex halimus L. (Ah) aerial parts against benzene (BZ) intoxication in liver rats.

Methods: 30 male albino rats were divided into five groups of 6 rats each: Control, Ah, BZ, AhP+BZ, and BZ+AhC. BZ (100 mg/kg b.w) was added in drinking water for 15 weeks. Aqueous extract of Atriplex halimus was received intragastrically during the last 30 days of BZ exposure for curative treatment (AhC) and all the duration of BZ exposure for preventive treatment (AhP). At the end the experiment, body weight gain and relative liver weight were estimated and liver enzyme markers (AST, ALT, ALP and LDH) were analysed by spectrophotometry. Histopathological studies on hepatic tissue were also performed by the method of Hematoxylin and Eosin staining.

Results: Benzene administrated to rats caused an alteration in physiological parameters (body and organs weigh) and hepatic enzymes markers (AST, ALT, ALP and LDH). In addition, Histopathological studies showed a massive degeneration in liver tissue in BZ-exposed rats. However, treatment by Atriplex halimus especially preventive effect ameliorated most of the adverse effects induced by benzene. Ah restored the altered of physiological, biochemical and histopathological changes.

Conclusion: The present study suggests that Atriplex halimus extract could be a substantially promising hepatoprotective agent against benzene toxic effects and may be against other hepatotoxic chemical or drugs.

Keywords: Atriplex halimus, Benzene, hepatotoxicity, Rats.
Preparation and Evaluation of Chewable Tablets of Syzygium cumini Seed Powder
Authors: Palakurthi Sushesh Srivatsa , Jakka Deeksha , Singh Harpreeth , Bollavaram Sahithi , B Sininandini , Pinnamraju Durga Nitya , Konde Abbulu
Published: May 2020

Aim of this study is to develop chewable tablets of Syzygium cumini seed powder. It has been chosen to do so as there are no oral solid dosage forms of this seed powder developed so far. There are numerous health benefits and nutrient properties of this seed powder, thus it can be used as a nutraceutical. Phytochemical screening of the Syzygium cumini seed powder has been conducted and the various phyto constituents present were detected. Seven different formulations have been developed by direct compression method out of which five were optimized. All these formulations were developed with Syzygium cumini seed powder as the active ingredient and lactose, acacia, glucose, talc, magnesium stearate, hydroxy propyl methyl cellulose, sodium alginate, guar gum and stevia were used as excipients. Various evaluations tests were performed to check the stability of the chewable tablets. Fourier Transform Infrared Spectroscopy (FTIR) analysis was conducted to check the interactions among the seed powder and the excipients. Anti-bacterial activity of the chewable tablets was tested against three different species of bacteria (Escherichia coli and Bacillus subtilis) by agar diffusion method. It is concluded that the Syzygium cumini seed powder and the developed chewable tablets were active against Escherichia coli and Bacillus subtilis.    

Keywords: Syzygium cumini, Chewable tablet, anti-bacterial activity
Total Phenolic Contents and Antioxidant Capacity of Aqueous Extract from Pituranthos scoparius (Coss. & Dur.) Growing in Algeria
Authors: Karbab Ahlem , Mokhnache Kamel , Arrar Lekhmici , Charef Noureddine
Published: May 2020

This study aims to estimate the total phenolics, flavonoids and tannins contents then to investigate both in vitro antioxidant capacity models of aqueous extract (AqE) from the stems of Pituranthos scoparius, growing in Algeria. Total polyphenol contents were determined using Folin Ciocalteu's reagent; flavonoids were quantified employing the AlCl3 and method tannins using haemoglobin precipitation test. The in vitro antioxidant property was assessed by DPPH-scavenging radical and lipid peroxidation assays. The results revealed that aqueous extract presented a high total phenolic and tannins contents with values of 150.89 ± 0.68 mg GAE (gallic acid equivalent)/g and 71.24 ± 0.09 mg TAE (tannic acid equivalent)/g dry extract, respectively. This extract show an essential effect toward DPPH-scavenging assay and lipid peroxidation inhibition with 96.19 ± 0.00 µg/mL, 91.53 ± 0.98 %, respectively. This study indicates that the aqueous extract from Pituranthos sciparius has potent antioxidant effects and may prove to be of latent health benefit as well as supplementary sources for natural antioxidants drugs.

Keywords: Pituranthos scoparius, aqueous extract, antioxidant activity, phenolic compounds.
Reassessing the Restorative Prospectives of the King of Spices Black Pepper
Authors: Goswami Anindya , Malviya Neelesh
Published: May 2020

Since ages, spices have been a crucial portion of human diets and trade. The bioactive principles in attendance are of noteworthy merit due to their advantageous probable against an array of disorders. Black pepper, amid piperine as its foremost element, holds affluent phytochemistry and also incorporates a number other important compounds like alkaloids, volatile oils and oleoresins. Piper nigrum is an imperative welfare spice owed to its anti-carcinogenic, antimicrobial, antioxidant apparent and gastro-defensive workings. Piperine also show evidence of speckled pharmacological characteristics like antidepressant, anti-inflammative, immunomodulatory, anticonvulsant, antihypertensive, antitumor, anti-tussive, pain reducing, antidiarrheal, antispasmodic, and cholesterol worsening . Piperine augments bioavailability of quite a few drugs and nutrients by restraining a variety of metabolising enzymes. This review is aimed to provide restructured information in recent progression of pharmacognosy, chemistry and pharmacological behavior of this miraculous King of Spices.

Keywords: Black Pepper, Piperine, Antioxidant, Bioavailability, King of Spices
Amplification of quadratic Hamiltonians
Authors: Arenz Christian , Bondar Denys I. , Burgarth Daniel , Cormick Cecilia , Rabitz Herschel
Published: May 2020

Speeding up the dynamics of a quantum system is of paramount importance for quantum technologies. However, in finite dimensions and without full knowledge of the details of the system, it is easily shown to be impossible. In contrast we show that continuous variable systems described by a certain class of quadratic Hamiltonians can be sped up without such detailed knowledge. We call the resultant procedure Hamiltonian amplification (HA). The HA method relies on the application of local squeezing operations allowing for amplifying even unknown or noisy couplings and frequencies by acting on individual modes. Furthermore, we show how to combine HA with dynamical decoupling to achieve amplified Hamiltonians that are free from environmental noise. Finally, we illustrate a significant reduction in gate times of cavity resonator qubits as one potential use of HA.
LA DOBLE FACETA DE LA LIBERTAD DE TRABAJO Y SU PROTECCIÓN EN LA CONSTITUCIÓN CHILENA
Authors: Herrera Vergara Juan Pablo
Published: May 2020

Tras el advenimiento del derecho del trabajo, en el siglo XX el nuevo constitucionalismo permite una e cacia plena de los derechos fundamentales en la empresa. En dicho contexto, mediante una misma disposición como es el artículo 19 número 16, se puede gra car el cruce en nuestra Constitución Política de los derechos fundamentales de tra- bajadores y empleadores.
Políticos de Deus: análise das campanhas de evangélicos eleitos para Deputado Federal por São Paulo (2010, 2014 e 2018)
Authors: Alves Mércia , Leine Cassotta Priscilla
Published: May 2020

O artigo discute a inserção de evangélicos na política partidária e eleitoral, problematizando a utilização que esses candidatos fazem dos meios de comunicação em suas campanhas. Busca-se identificar as principais estratégias utilizadas por esses candidatos para que sejam reconhecidos pela audiência como uma liderança cristã. Foram analisados os programas veiculados pelo Horário Gratuito de Propaganda Eleitoral dos candidatos evangélicos eleitos para Deputados Federais por São Paulo nas eleições de 2010, 2014 e 2018 a partir dos conceitos de formação ideológica e interdiscursividade, tal como abordados pelos autores da análise do discurso. Os principais resultados encontrados foram uma oferta eleitoral comum, suprapartidária e independente de denominação religiosa, baseada na preservação de valores tradicionais e no combate a um inimigo comum, que representa a diluição desses valores.
Book review: “Innovation in financial restructuring: Focus on signals, process and tools”
Authors: Gouiaa Raef
Published: May 2020

This review covers the book titled “Innovation in financial restructuring: Focus on signals, processes and tools”, which was written by Marco Tutino and Valerio Ranciaro (Virtus Interpress, 2020; ISBN: 978-6-177309-10-8). The review shortly outlines the fundamental questions researched in the book, pays attention to its strong sides and issues that will be, by the reviewer’s point of view, most interesting for the reader
Inequality and welfare state clientelism in Bosnia and Herzegovina
Authors: Obradovic Nikolina , Filic Goran
Published: May 2020

Inequality in Bosnia and Herzegovina (BiH) is rampant, manifested not only
through one of the highest Gini coefficients in Europe but also in unequal
access to social benefits and services. We find this to be an outcome of
BiH?s entitygovernment social policy, which has been created to serve ethnic
clientelistic politics. As the country?s former social protection system
adjusted in the immediate post-civil war period to a new asymmetric
government structure made of two entities, Federation of Bosnia and
Herzegovina and Republika Srpska, it helped the main ethnic political
parties preserve their power and ethnic divisions. This was achieved through
a comprehensive system of status-based social benefits, most notably
war-related social benefits granted on the basis of ethnic and military
service affiliation. As such, in both BiH?s entities the system of social
protection is an instrument of political control that generates inequality
by treating certain social groups differently in terms of access to and
level of benefits, while excluding much of the population. The process is
found to be endogenous; in other words, maintaining inequality in access to
social benefits is essential for preserving clientelistic policy, and vice
versa.
Análisis sobre la planeación financiera de los estudiantes de la Lic. en Administración, Córdoba, España
Authors: Reus González Nadia Natasha
Published: May 2020

Para lograr una mejor situación financiera en los estudiantes de la Universidad Loyola Andalucía, específicamente del Campus de Córdoba, España, es importante tener en cuenta los gastos que implica cursar una licenciatura, en este caso en Administración. Se aplicó un instrumento de medición de 21 ítems sobre gastos, egresos, ahorro, presupuesto y control de gastos para estudiantes inscritos en la universidad y en la carrera en cuestión durante el calendario 2015-B. El trabajo de investigación mostró las variables y resultados. El estudiante, de manera empírica, lleva a cabo la administración respecto de su economía, basada en sus ingresos, los cuales no necesariamente provienen de una fuente propia de trabajo. Finalmente, se analizó cómo administra y cuáles son las estrategias de planeación financiera que lleva a cabo.
САМОИДЕНТИФИКАЦИЯ ЯЗЫЧНИКОВ В СОВРЕМЕННОЙ РОССИИ: ФЕНОМЕН ИМЕНОСЛОВА (ПО МАТЕРИАЛАМ ПОЛЕВЫХ ИССЛЕДОВАНИЙ)
Authors: Samoilova Galina , Surovegina Ekaterina , Shizhensky Roman
Published: May 2020

Статья посвящена изучению феномена именослова и имянаречения в языческих движениях современной России. Исследуются принципы выбора и присвоения сакрального имени как средства самовыражения и самоидентификации новых язычников, их дистанцирования от действующего, традиционно сложившегося на основе православной культуры именника. Установлено, что ономастическое пространство неоязычества не повторяет и не накладывается на древний языческий именник. Ориентируясь на традиционный языческий ономастикон, современное язычество отражает собственные предпочтения в выборе имени. Выбор онима и обряд имянаречения определяются новыми условиями существования и отношениями духовного мира современного человека. Преобладают имена, как правило, сложной структуры, с положительной семантикой. Аксиологическими маркерами феномена современного язычества выступают понятия добра, света, славы, этические категории, переоценка собственного мировоззрения и мировидения через призму нового имени. Имя, по мнению, респондентов определяет изменения в их жизни, помогает расширению кругозора, самопознанию, улучшению качества жизни.
Выступая в качестве социального, культурного и индивидуального маркера, новое имя является средством самоидентификации не только его отдельных носителей, но и новых языческих сообществ в целом. Ономастическое пространство современного язычества объединяет представителей неоязычества любого варианта, течения, толка, позволяя распознавать «своих» и «чужих» – других, не имеющих отношения к современному язычеству.
Проблемы хирургического лечения функциональной трикуспидальной недостаточности
Authors: Skopin I.I. , Latyshev M.S.
Published: May 2020

Результаты применения различных методик коррекции функциональной трикуспидальной недостаточности свидетельствуют о том, что до сих пор не существует методики, позволяющей в полной мере обезопасить пациентов от факторов, способствующих возврату регургитации. Нарастание регургитации со временем после неэффективной реконструкции трикуспидального клапана приводит к точке невозврата , когда процесс изменения архитектоники желудочка становятся необратимыми и единственным вариантом лечения пациентов становится выполнение реоперации. Она проводится в условиях тяжелых расстройств внутрисердечной гемодинамики и характеризуется высокой летальностью. В статье представлен обзор основных хирургических техник коррекции функциональной трикуспидальной недостаточности I и IIIb типов (по классификации A. Carpentier).
Состояние проблемы повышения тромборезистентности искусственных материалов и изделий, предназначенных для контакта с кровью, в ФГБУ «НМИЦССХ им. А.Н. Бакулева» МЗ РФ
Authors: Novikova S.P.
Published: May 2020

Приведены этапы поступательного решения проблемы придания тромборезистентных и других необходимых свойств минимальной хирургической пористости, антимикробности, оптимальных прочностных характеристик материалам и имплантируемым изделиям, разработанным и применяемым в настоящее время в сердечно-сосудистой хирургии. Дана оценка предыдущим работам. Указана роль материалов, конструкции изделий, гемодинамических параметров потока крови в протезах кровеносных сосудов и искусственных клапанах сердца. Так как до настоящего времени детально не выяснена причина образования тромбов на поверхности инородных материалов, истинно тромборезистентный материал еще не создан. Тем не менее предпринимаются попытки учесть все большее число различных факторов, влияющих на тромбообразование. Тканеинженерные, клеточные технологии и другие приемы биотехнологий могут дать новые варианты научного поиска. Рассмотрены различные методы оценки эффективности способов модифицирования материалов. Показано, что для создания наиболее перспективных материалов целесообразно проводить комплексные медико-биологические испытания in vitro, ex vivo, in vivo. Приведены экспериментально подтвержденные положительные результаты испытаний in vivo модифицированных протезов кровеносных сосудов, манжет для искусственных клапанов сердца и других изделий для клинического применения. В НМИЦССХ им. А.Н. Бакулева МЗ РФ организовано мелкосерийное производство протезов кровеносных сосудов, кардиохирургических заплат с покрытием БАСЭКС , БАСЭКС-SP , БАСЭКС-Patch .
Среднеотдаленные результаты после операции Ross у детей
Authors: SHatalov K.V. , Abdurazakov M.A. , Arnautova I.V. , Dzhidzhihiia K.M.
Published: May 2020

Цель: анализ среднеотдаленных и отдаленных результатов операции Ross у детей с врожденными пороками аортального клапана. Материал и методы. В период с 2005 по 2018 г. операция Ross была выполнена у 44 пациентов с врожденной патологией аортального клапана. Средний возраст составил 3,22,4 года, средняя масса тела 14,85,5 кг. Показанием для операции был стеноз аортального клапана (63,7 случаев), аортальная недостаточность (20,3), комбинированный порок аортального клапана (16). Семи пациентам с клапанным и подклапанным стенозом аортального клапана выполнена операция RossKonno. Результаты.Средний период наблюдения составил 4,53,2 года. Ранняя послеоперационная летальность составила 4,5 (n2), отдаленная летальность 7,1 (n3). Выживаемость по кривой KaplanMeier через 1 год и на протяжении всего периода наблюдения составила 89. Эхокардиографическое исследование в отдаленном послеоперационном периоде показало отсутствие клинически значимой недостаточности или стеноза на аутографте у всех, кроме одного пациента. Повторные вмешательства потребовались у 7 (17,9) пациентов, все по поводу стеноза кондуита правого желудочка легочной артерии. Свобода от всех вмешательств по кривой KaplanMeier через 1, 5 и 7 лет составила 92, 78 и 63 соответственно. Заключение. Наш более чем 10-летний опыт применения операции Ross показал хорошие результаты со сравнительно низкой ранней и отдаленной послеоперационной летальностью, в том числе в группе детей младшего возраста со сложными комбинированными поражениями выводного отдела левого желудочка. Однако развитие дисфункций легочного аутографта и кондуитов правого желудочка легочной артерии достаточно часто требует повторных вмешательств. В связи с этим необходимы дальнейшее наблюдение и сравнительный анализ с другими методами лечения пороков аортального клапана у детей разных возрастных групп для установления оптимальной хирургической тактики.
Результаты протезирования корня аорты аортальным аллографтом и легочным аутографтом (операция Росса) при активном инфекционном эндокардите аортального клапана у детей
Authors: Fedoseikina M.I. , Titov D.A. , Britikov D.V. , Babenko S.I. , Muratov R.M.
Published: May 2020

Цель исследования представить опыт хирургического лечения инфекционного эндокардита у детей с использованием аллографтов и аутографтов в позиции корня аорты. Материал и методы. В 11 случаях в позицию корня аорты были имплантированы аортальные аллографты, в 4 легочные аутографты (операция Росса). В 7 (47) случаях операция носила повторный характер. Положительный посев крови был получен в 7 случаях. У 9 детей имелось узкое фиброзное кольцо аортального клапана. Все пациенты поступили в активной стадии заболевания, операции выполнялись по витальным показаниям. Результаты. Госпитальная летальность составила 13. Время наблюдения 15 лет. Свобода от тромбоэмболических и геморрагических осложнений в течение всего периода наблюдения составила 100. В сроки наблюдения до 15 лет трансклапанный пиковый градиент на аортальном аллографте составляет в среднем 13,53,7 мм рт. ст. Гемодинамически значимой регургитации у пациентов не отмечено. Свобода от дисфункции аллографта в позиции выводного отдела левого желудочка по разным причинам в сроки до 15 лет после операции составляет 93,3. Дисфункции аутографта, имплантированного по методике свободный корень , в отдаленном послеоперационном периоде не выявлено. Свобода от протезного эндокардита к 5-му году после операции составила 100, к 10-му 91. Заключение. Девитализированные криосохраненные клапаны представляются многообещающей альтернативой у детей. Имплантация бескаркасного биологического протеза позволяет решить проблему узкого, разрушенного фиброзного кольца аортального клапана и снизить риск реинфекции.
asd111
Authors: Fedorchenko Alexander
Published: May 2020

asd
The Image of a Women in Modern Advertising: the Main Trends of 2016–2019
Authors:   Pacific State University, Potapchuk Yelena Yuryevna , Avdyushina Karina Sergeyevna ,   Pacific National University
Published: May 2020

The paper discusses the latest trends in creating female images in advertising communication on the example of well-known world brands. When analyzing the Kenzo, Nike, and Dove video ads in 2016–2019, the authors find a new perception of a woman emerging in modern society which becomes communication trends such as «digital naturalness» (the use of female images without retouching and any other digital processing), «body-positive» (acceptance of one’s real appearance, respectful attitude to the natural state of your or other person’s body), «empowerment» (attention to the existing internal strength of a person), which are based on the ideas of rational feminism. The authors of this paper explain the appearance of female images, which are less artificial and more easily understandable for the target audience, in the video advertising of recent years.
Excursions in the Smolensk School for the Blind in the Academic Year 1924–1925
Authors:   Smolensk State University, Mezhentseva Galina Nikolayevna
Published: May 2020

The paper presents an analysis of excursion activities conducted by the head of the Smolensk regional blind school B.I. Kovalenko in the preschool and primary school groups in 1924–1925. The main methods are searching for documents in the State Archive of the Smolensk region and studying, evaluation, comparative analysis with related documents. As part of the study, it was found that during the excursions blind children learned to navigate and move independently in the premises of their school, on the territory of the school site, garden and vegetable garden. The children subsequently mastered the space of the city streets, its diverse structure, and attractions, industrial, cultural and educational facilities. Sensory development had an important place in the observation of changes in nature during the changing seasons. Excursions at school for the blind were practically significant and the introductory ones started from the first form at school. The research defines the methodology for conducting excursions in numerous modifications, since excursions combined the educational process at school with the real life, breaking the circle of isolation of blind people. Archival materials are published for the first time.
“No te me caigas hoy”
Authors: Rodríguez Malvina Eugenia , Avendaño Manelli Carla Fernanda
Published: May 2020

.
Dos puntas para abordar la pandemia: control y dualismo
Authors: Duarte Ezequiel
Published: May 2020

.
“Algo personal”
Authors: Lamanna Gabriel
Published: May 2020

.
Del coronavirus al Buen Vivir
Authors: Mora Aura Isabel
Published: May 2020

.
La pandemia, la vida cotidiana y la Universidad
Authors: Bernat María Sofía
Published: May 2020

.
Santa Cruz en la pandemia
Authors: Fernández Alfredo
Published: May 2020

.
Incidencias del Covid-19 en Ecuador
Authors: Bajaña Mendieta Inés De la Luz
Published: May 2020

.
Alemania en Pandemia
Authors: Fuertes Zapatero Ana
Published: May 2020

La vivencia de la pandemia del covid-19 me ha pillado residiendo en Alemania, exactamente en Múnich, Estado de Baviera. Por lo que entiendo que mi experiencia es interesante, no por mí, sino porque el país en el que me encuentro es observado a ambos lados del Atlántico debido a su modelo de gestión ante esta crisis sanitaria.
El extranjero en pandemia
Authors: González Fernanda
Published: May 2020

Escribo desde Malta, una isla ubicada en el mediterráneo en medio de Europa y África o más claro aún, entre Libia e Italia. Vivo en este país hace tres años. Desde entonces han pasado varios sucesos nacionales relevantes: el asesinato de la periodista Dapne Caruana con un carro bomba, Valletta como capital europea de la cultura, el apuñalamiento mortal a Hugo Chetcuti, uno de los empresarios más rico del país, justo al frente de su emporio, y la renuncia del primer ministro, Joseph Muscat, tras la judicialización de su jefe de gabinete por la muerte de Caruana.

Estos hechos mantuvieron a la isla en una conmoción tras otra por un período de tiempo. Hasta ahora fue un lugar dinámico con disputas políticas y sociales comparables con las de cualquier otro país remoto. En estos tiempos, la isla también coincide con el resto del mundo en la extensión de la Pandemia del Covid 19 y en la consigna implícita: cualquiera puede ser sospechoso. Todos podríamos tener el virus, desconfiamos unos de los otros.
Calendario
Authors: García Mayer Simón
Published: May 2020

.
PENYELENGGARAAN PEMBELAJARAN IPA BERBASIS PENDEKATAN STEM DALAM MENYONGSONG ERA REVOLUSI INDUSTRI 4.0
Authors: Grahito Wicaksono Anggit
Published: May 2020

Pendidikan berbasis revolusi industri 4.0 memerlukan alternatif solusi yang membuat lembaga pendidikan harus selalu memadukan metode inovatif untuk meningkatkan pengajaran dan pembelajaran. Tujuan dari penelitian ini adalah untuk menganalisis aspek-aspek penunjang pembelajaran IPA serta cara mengimplementasikannya dalam menyongsong era revolusi industri 4.0. Metode Penelitian ini mengunakan metode library research. Hasil penelitian ini adalah (1) aspek-aspek penunjang dalam pembelajaran IPA yang memenuhi tuntutan revolusi industri 4.0 adalah menggunakan model pembelajaran inovatif berbasis masalah/proyek, menggunakan pendekatan yang melibatkan unsur sains, teknologi, dan masyarakat, serta dapat meningkatkan keterampilan abad 21 antara lain berpikir kritis, pemecahan masalah, dan kreativitas; dan (2) Implementasi pembelajaran IPA berbasis project based learning yang dikombinasikan dengan pendekatan STEM adalah contoh implementasi teknologi ramah lingkungan yang dapat meningkatkan kreativitas peserta didik dalam mengelola limbah sebagai sumber energi baru terbarukan.