bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of efficiency indicators and its related aspects on the market return: An applied study on Palestine Stock Exchange
Authors: Awwad Bahaa , Razia Bahaa
Published: August 2021

The study deals with the efficiency of the Palestine Stock Exchange (PSE) indicators that explain the market return. The data published in the Palestine Exchange and the Palestinian Monetary Authority during 2010–2018 have been analyzed. The multiple regression method has been employed to determine the correlation between efficiency indicators and market return. However, the findings, on the one hand, determined that there was no statistically significant effect of efficiency indicators measured by the stock turnover rate and the market capital ratio. On the other hand, they demonstrated the impact of market concentration on market return, which shows a widespread weakness in the efficiency indicators. Therefore, PSE does not enjoy the required levels of efficiency even at the weak level. The study explored the absence of liquidity indicators required for market depth, speed of market response, and market concentration. Thus, the stock prices at the PSE become randomly moving, volatile, and unstable. Consequently, the outcomes of the aforementioned findings recommended the necessity to take the essential measures that activate the elements of market efficiency to reflect the available returns according to the scientific method. The paper also recommends that there should be incentives that motivate and encourage institutions to raise their capital and put their securities into the stock exchange to enhance their role in achieving economic development. However, it should be mentioned that the increasing number of companies leads to an increase in investments as it contributes to the expansion of the market.
AcknowledgmentSpecial thanks to Palestine Technical University for their continued and valuable support.
Filozoficzne aspekty teorii duchowości ekologicznej papieża Franciszka w świetle filozofii tomistycznej
Authors: Mikucki Kazimierz
Published: August 2021

Artykuł jest próbą wyodrębnienia i ogólnego opisu aspektów filozoficznych, zawartych w teorii duchowości ekologicznej papieża Franciszka oraz porównania ich z myślą tomistyczną, rozwijaną przez jej polskich przedstawicieli w czasach współczesnych. Aspekty te dostrzeżono na gruncie wielu dyscyplin filozoficznych, ponieważ w tego typu duchowości chodzi o stosunek człowieka do najogólniej pojętej rzeczywistości realnej, czyli do samego siebie, przyrody, kultury i religii. W toku analizy obu stanowisk zauważono liczne analogie, a także pewne rozbieżności w sposobie widzenia przyrody, osoby ludzkiej, kultury (etyki) oraz religii, które przynajmniej częściowo można tłumaczyć niejednoznacznością niektórych sformułowań papieskich.

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Zgłoszono: 19/08/2020. Zrecenzowano: 26/09/2020. Zaakceptowano do publikacji: 18/10/2020
Emerging Role of Circular RNAs in Kidney Diseases in Nephrology
Authors: Ma Cong , Luan Junjun , Kopp Jeffrey B. , Zhou Hua
Published: August 2021

Background:

Circular RNAs (circRNAs) have been identified to be involved in a variety
of human diseases such as cancers, cardiovascular diseases, and autoimmune diseases. In recent
years, the role of circRNAs in the development of kidney diseases in nephrology has been gradually
recognized.

Objective:

We updated and described the current status of circRNAs in kidney diseases in nephrology.
We particularly focused on the roles and mechanisms of circRNAs in systemic lupus erythematosus
and lupus nephritis.

Methods:

We summarized recent reports published on PubMed, Web of Science, Scopus, Scielo
databases using keywords circRNAs, kidney diseases or renal diseases, or systemic lupus erythematosus.

Results:

Studies of circRNAs in certain kidney diseases, such as acute kidney injury, focal segmental
glomerulosclerosis, idiopathic membranous nephropathy, IgA nephropathy, diabetic nephropathy,
hypertensive renal damage, and particular lupus nephritis address the function and pathogenesis
of circRNAs. Mechanisms of circRNAs in the above human kidney diseases so far have focused
on the role of sponging microRNAs and regulating the expression of target genes. Moreover,
circRNAs have been detected in blood, urine, and kidney tissue samples. These results suggest that
circRNAs can serve as biomarkers for the diagnosis and monitoring of the progression of kidney
diseases.

Conclusion:

CircRNAs play important roles in the pathogenesis, diagnosis, and treatment of kidney
diseases emphasizing lupus nephritis in nephrology.
Ionic Channels as Potential Targets for the Treatment of Autism Spectrum
Disorder: A Review
Authors: da Silva Bagnólia Araújo , da Silva Pablo Rayff , do Nascimento Gonzaga Thallita Karla Silva , Maia Rayana Elias
Published: August 2021

:

Autism spectrum disorder (ASD) is a neurological condition that directly affects brain
functions and can culminate in delayed intellectual development, problems in verbal communication,
difficulties in social interaction, and stereotyped behaviors. Its etiology reveals a genetic basis
that can be strongly influenced by socio-environmental factors. Ion channels controlled by ligand
voltage-activated calcium, sodium, and potassium channels may play important roles in modulating
sensory and cognitive responses, and their dysfunctions may be closely associated with neurodevelopmental
disorders such as ASD. This is due to ionic flow, which is of paramount importance to
maintaining physiological conditions in the central nervous system and triggers action potentials,
gene expression, and cell signaling. However, since ASD is a multifactorial disease, treatment is directed
only to secondary symptoms. Therefore, this research aims to gather evidence concerning the
principal pathophysiological mechanisms involving ion channels in order to recognize their importance
as therapeutic targets for the treatment of central and secondary ASD symptoms.
Developments and Scope of Space Food
Authors: Grover Yashmita , Bhasin Jagriti , Dhingra Bhavika , Nandi Sonali , Hansda Mamta , Sharma Ruchi , Paul Veena , Idrishi Rubeka , Tripathi Abhishek Dutt , Agarwal Aparna
Published: August 2021

:

Humans have conducted numerous space missions in past decades and its success depends
upon many factors, including astronaut health as the major factor. Health and nutrition are
two vital components of life derived from food which helps in keeping one’s body alive, nourished
as well as energetic, including the astronauts during their long-duration manned missions. With the
advancement in research and technology, it became possible to include a wide variety of dishes in
the space menu, with most of them being similar to those eaten on the earth. This review highlights
the evolution of space food starting from mission Mercury to the current International Space Station.
Furthermore, it also enlightens and focuses on types of space food, its packaging considerations,
and vitamin A-rich energy balls as potential space food. Many deleterious effects of outer
space explorations have been observed on the human body, such as loss of body mass, visionrelated
changes, loss in bone density, and even anemia. To overcome these issues, various considerations
must be followed while designing space food. The nutritional requirement plays an important
role in a space mission. Various foods have the potential to overcome the limitations caused by a
space mission. Thus, while developing space food, various parameters should be taken into consideration,
such as deficiencies and illness. The food should be compact, bite-sized, easily digestible,
and shelf-stable. Further research is required to better gain insight into the technological advancements
while considering the nutritional status and requirements of astronauts in a space mission.
Is Proximal Tibia Sufficient for Accurate Measurement of Tibial Slope Angles
on Three-dimensional Tomography-based Anatomical Models?
Authors: Tanoğlu Oğuzhan , Subaşı İzzet Özay , Gökgöz Mehmet Burak , Arıcan Gökhun
Published: August 2021

Background:

Tibial slope measurements performed using only the proximal part of
tibia ignore the native tibial anatomical axis. Our first aim is to measure the native medial, lateral
and total tibial slope angles of gender groups using the whole tibial anatomical axis on computerized
tomography-based three-dimensional anatomical models. The second aim is to determine the
correlation between proximal and whole tibial anatomical axis for measurement of medial, lateral,
and total tibial slope angles.

Methods:

We randomly selected 100 females and 100 males between 18-60 years of age. Three-dimensional
anatomical models of right and left tibia were created. The gender-specific differences
of medial, lateral, and total tibial slope angles according to proximal and whole tibial anatomical
axis were measured. Correlation coefficients (r) of medial, lateral, and total tibial slope angles measured
with proximal and whole tibial anatomical axis were calculated.

Results:

The mean age was 47.1 years. A statistically significant difference was observed between
female (7.1 ± 3) and male (8.2 ± 2.5) groups in terms of mean lateral tibial slope angles according
to the whole tibial anatomical axis (p=0.008). A strong correlation between proximal and whole
tibial anatomical axis for all tibial slope angle measurements was detected.

Conclusion:

The method we determined for 3D measurement of medial, lateral and total tibial
slope angles using proximal tibial anatomical axis has a strong correlation with slope angles measured
in accordance with the whole tibial anatomical axis. Our 3D tibial slope angle measurement
method on the proximal tibia has high reliability and could be used in the daily practice.
Mechanisms Involved in Neuroprotective Effects of Transcranial Magnetic
Stimulation
Authors: Caballero-Villarraso Javier , Medina Francisco J. , Escribano Begoña M. , Agüera Eduardo , Santamaría Abel , Pascual-Leone Alvaro , Túnez Isaac
Published: August 2021

:

Transcranial Magnetic Stimulation (TMS) is widely used in neurophysiology to study
cortical excitability. Research over the last few decades has highlighted its added value as a potential
therapeutic tool in the treatment of a broad range of psychiatric disorders. More recently, a number
of studies have reported beneficial and therapeutic effects for TMS in neurodegenerative conditions
and strokes. Yet, despite its recognised clinical applications and considerable research using
animal models, the molecular and physiological mechanisms through which TMS exerts its beneficial
and therapeutic effects remain unclear. They are thought to involve biochemical-molecular
events affecting membrane potential and gene expression. In this aspect, the dopaminergic system
plays a special role. This is the most directly and selectively modulated neurotransmitter system,
producing an increase in the flux of dopamine (DA) in various areas of the brain after the application
of repetitive TMS (rTMS). Other neurotransmitters, such as glutamate and gamma-aminobutyric
acid (GABA) have shown a paradoxical response to rTMS. In this way, their levels increased
in the hippocampus and striatum but decreased in the hypothalamus and remained unchanged in
the mesencephalon. Similarly, there are sufficient evidence that TMS up-regulates the gene expression
of BDNF (one of the main brain neurotrophins). Something similar occurs with the expression
of genes such as c-Fos and zif268 that encode trophic and regenerative action neuropeptides. Consequently,
the application of TMS can promote the release of molecules involved in neuronal genesis
and maintenance. This capacity may mean that TMS becomes a useful therapeutic resource to antagonize
processes that underlie the previously mentioned neurodegenerative conditions.
Clinical Efficacy of Remdesivir and Favipiravir in the Treatment of
COVID-19 Patients: Scenario so far
Authors: Das Rina , Saini Manisha , Rana Minakshi , Bhatti Karun , Mehta Dinesh Kumar , Chidurala Ram Mohan
Published: August 2021

:

The novel SARS-CoV-2 is a new disease that has caused severe destruction to human
lives across the globe, including infection, mortality and financial crises, for which, scientific researchers
have been directed towards the development of treatment and controlling measures
against coronavirus. Currently, there has been no approved drug for the treatment of the disease,
but several antiviral drugs have shown therapeutic effects from which, remdesivir and favipiravir
are two such drugs. These drugs have shown some therapeutic potential in the treatment of
COVID-19 by inhibiting viral enzyme RNA-dependent RNA polymerase. The purpose of this systematic
review is to provide an overview of the effectiveness of these two drugs based on the clinical
trials reported in current published data.
Attitudes of Patients and Health Professionals Regarding Screening Algorithms: Qualitative Study
Authors: Oxholm Christina , Christensen Anne-Marie Soendergaard , Christiansen Regina , Wiil Uffe Kock , Nielsen Anette Søgaard
Published: August 2021

Background

As a preamble to an attempt to develop a tool that can aid health professionals at hospitals in identifying whether the patient may have an alcohol abuse problem, this study investigates opinions and attitudes among both health professionals and patients about using patient data from electronic health records (EHRs) in an algorithm screening for alcohol problems.

Objective

The aim of this study was to investigate the attitudes and opinions of patients and health professionals at hospitals regarding the use of previously collected data in developing and implementing an algorithmic helping tool in EHR for screening inexpedient alcohol habits; in addition, the study aims to analyze how patients would feel about asking and being asked about alcohol by staff, based on a notification in the EHR from such a tool.

Methods

Using semistructured interviews, we interviewed 9 health professionals and 5 patients to explore their opinions and attitudes about an algorithm-based helping tool and about asking and being asked about alcohol usage when being given a reminder from this type of tool. The data were analyzed using an ad hoc method consistent with a close reading and meaning condensing.

Results

The health professionals were both positive and negative about a helping tool grounded in algorithms. They were optimistic about the potential of such a tool to save some time by providing a quick overview if it was easy to use but, on the negative side, noted that this type of helping tool might take away the professionals’ instinct. The patients were overall positive about the helping tool, stating that they would find this tool beneficial for preventive care. Some of the patients expressed concerns that the information provided by the tool could be misused.

Conclusions

When developing and implementing an algorithmic helping tool, the following aspects should be considered: (1) making the helping tool as transparent in its recommendations as possible, avoiding black boxing, and ensuring room for professional discretion in clinical decision making; and (2) including and taking into account the attitudes and opinions of patients and health professionals in the design and development process of such an algorithmic helping tool.
PENGARUH KOREKSI ATENUASI RADAR CUACA TERHADAP PERHITUNGAN ESTIMASI CURAH HUJAN DI JAWA TIMUR
Authors: Kosasih Ahmad , Hartono Hartono , Jatmiko Retnadi Heru
Published: August 2021

Rainfall estimation using band C weather radar creates uncertainty in the results of its estimation accuracy. The cause is meteorological and non-meteorological disturbances that affect the reflectivity raw data (dBz), one of which is attenuation due to rain, especially with heavy and very heavy intensity. This study aims to evaluate the attenuation correction ability of the reflectivity raw data generated by the weather radar against the calculation of rainfall estimates at the Juanda Sidoarjo Meteorological Station, as well as the best attenuation correction coefficient to be applied in the processing of rainfall estimates by weather radar. The method used to perform attenuation correction is Z-based attenuation correction (ZATC). The calculation of attenuation correction using the ZATC method uses several α and β coefficients while the Z-R relation (Z = 200R1.6) is used to calculate the estimated rainfall before and after attenuation correction. The results showed that the attenuation correction of the C band weather radar reflectivity raw data was able to provide an increase in the accuracy of rainfall estimation where in the estimation of rainfall from a weather radar without the attenuation correction stage of the raw data, an accuracy value of 70.8% was obtained, while applying the attenuation correction using several The α and β coefficients obtained an increase in the accuracy of rainfall estimation between 72.5% to 86.9%. The best α and β coefficients for attenuation correction of weather radar reflectivity (dBz) can be applied in obtaining a more accurate rainfall estimate, namely the α and β coefficients according to Krämer and Verworn which are able to provide an increase in the accuracy of rainfall estimation by 16.1%.
POSSIBILITY STUDY OF IMPLEMENTING VERTICAL CONSTRUCTED WETLAND FOR DOMESTIC WASTE WATER TREATMENT IN URBAN KAMPONG
Authors: Sutanto Haryati , Bawole Paulus
Published: August 2021

The Indonesian Ministry of Environment in 2014 released study results that 60-70% of rivers in Indonesia have been polluted by domestic wastewater, which is not treated properly. Improper and inadequate wastewater treatment not only pollutes water resources and damages ecosystems, but can also pose a significant public health risk. The development of spontaneous settlements in urban kampong makes the environmental quality within the settlements getting worse and many people consider that the area of urban kampong is not habitable. The efforts to treat wastewater before being discharged into water bodies are very important. The study of "vertical constructed wetland" model using water plants which are also ornamental plants can be considered as an alternative system for household wastewater treatment in kampong settlements.  The objective of the research is to develop an alternative model of wastewater treatment that can overcome the obstacles of implementing a wastewater treatment system in terms of cost and availability land. The result shows that the removal efficiency of BOD, phosphate and total coliform are 71.64%, 50,92% and 99.67% respectively. Since the research is still being conducted on a laboratory scale, the further study must be developed with real case studies in low income community settlements in Kampung Kota. Additionally this research can give suggestions to local government an alternative policy to implement domestic waste water treatment plan in a densely populated settlement along the riverbank in the city.
El derecho a la muerte digital y la protección post mortem de los datos personales: nuevas prerrogativas aplicables al ecosistema digital
Authors: Peña Pérez Pascal
Published: August 2021

La protección de los datos personales ha generado nuevas prerrogativas aplicables al entorno digital, las cuales han sido acompañadas de mecanismos efectivos para su pleno ejercicio.  Los nuevos derechos digitales, tales como el derecho al olvido, el derecho a la portabilidad de los datos o el derecho a la muerte digital y los derechos sucesorales sobre datos que reposen en dispositivos físicos y en plataformas digitales, que constituyen la base de debates que han surgido en países con un mayor avance legislativo y jurisprudencial. Tal experiencia comparada nos permite evaluar como reaccionarían nuestros ordenamientos jurídicos a estos conflictos modernos que se suscitan alrededor de la protección de los datos personales.
Anguiano Espinosa, Griselda, El principio non bis in ídem en el Procedimiento Administrativo Sancionador en México, México, Bosch, 2021, 387 pp.
Authors: Fernández Ruiz María Guadalupe
Published: August 2021

Recensión del libro en comento.
La era de la posverdad democrática en México
Authors: Olivos Campos José René
Published: August 2021

El artículo tiene por finalidad presentar el estado actual de la democracia en México en tiempos de la expansión de la epidemia COVID-19, en la renovación de los cargos de elección popular, así como las posibles implicaciones en la jornada electoral de 2021, que involucra tensiones y retos para el sistema institucional democrático.
Uso de un sistema de apoyo de decisiones clínicas (DXplain) en estudiantes de Medicina
Authors: Martínez-Franco Adrián Israel , Vives-Varela Tania , Martínez-González Adrián , Sánchez Mendiola Melchor
Published: August 2021

Introducción: El diagnóstico es el reto principal en la labor del médico y es crucial para lograr resultados óptimos en los pacientes. Las tareas de un médico exigen diversos grados de habilidad, pero pocas tan complicadas de cultivar como la capacidad de llegar a un diagnóstico correcto. Los Sistemas de Apoyo a las Decisiones Clínicas (SADC) pueden ser destinados a apoyar este proceso durante la formación médica.

Objetivo: Explorar la opinión de los estudiantes de medicina sobre el uso de un SADC (DXplain) como material didáctico para el análisis de casos clínicos.

Método: Estudio observacional con un método mixto secuencial. Participaron estudiantes de Medicina de segundo año de 3 generaciones (n = 3,132) de la licenciatura de Médico Cirujano en la Facultad de Medicina de la Universidad Nacional Autónoma de México. Los estudiantes utilizaron un SADC (DXplain) en la asignatura de Informática Biomédica. Al final del curso, contestaron un cuestionario en línea de 12 enunciados con 4 opciones de respuesta: muy inadecuado, inadecuado, adecuado y muy adecuado. Se realizó la parte cualitativa del estudio con grupos focales. Para el análisis estadístico se utilizó la prueba X2.

Resultados: La mayoría de los usuarios (84.9%) encontró la inclusión del sistema DXplain a la asignatura de Informática Biomédica como adecuado o muy adecuado, y 92.3% recomendaría DXplain a los estudiantes para su aprendizaje. Al triangular los resultados cuantitativos y cualitativos, se encontraron 3 categorías relacionadas con el uso del DXplain: 1) profesores que apoyan su uso, 2) motivación para el razonamiento clínico y 3) utilidad para el aprendizaje.

Conclusiones: La opinión de los estudiantes fue favorable en relación con el uso de DXplain como material didáctico, en el nivel inicial de la carrera. Su uso debe tener una implementación eficiente, así como valorarse como complemento en el desarrollo del razonamiento clínico.
El reto de evaluar presentaciones orales: uso de una rúbrica en un posgrado de educación médica
Authors: Olvera López Adriana , Pompa Mansilla Maura , Maya López Mary Paola Janett , Hernández Flores María Dolores , García-Minjares Manuel , Sánchez Mendiola Melchor , Fortoul van der Goes Teresa
Published: August 2021

Introducción: se presentan los resultados de la aplicación de una rúbrica para evaluar presentaciones orales de proyectos en un posgrado en educación médica.

Método: el instrumento evaluó habilidades verbales, no verbales, ayudas visuales, contenido y organización. Se obtuvo evidencia de validez de sus resultados con análisis factorial de componentes principales; de fiabilidad, mediante alfa de Cronbach; desde el punto de vista psicométrico a través del modelo de Crédito Parcial de Rasch.

Resultados: se identificaron 3 grupos de habilidades en la presentación: diseño, control interno e interacción con la audiencia. Alta fiabilidad para todo el instrumento, correcto funcionamiento de las opciones de respuesta e independencia entre estimaciones de parámetros de ítems y parámetros de habilidad.

Conclusiones: la rúbrica es útil para evaluar las presentaciones de los estudiantes del posgrado en cuestión, dado que es un instrumento confiable y con evidencia de validez.
Efektivitas Larvasida Granul Ekstrak Etanol Daun Pisang Nangka (Musa x paradisiaca L.) terhadap Larva Nyamuk Aedes aegypti
Authors: Yuliana Anna , Rinaldi Rusdi Aris , Rahayuningsih Nur , Gustaman Firman
Published: August 2021

Musa x paradisiaca L. leaves are known to contain phenols, flavonoids, saponins, tannins, and other compounds that can be used as larvicides. This study aims to determine the effect of Musa x paradisiaca L leaves’ ethanol extract granules on the mortality of Aedes aegypti larvae. The Research was experimental in two stages of effectiveness testing, that are extract and granule formula effectiveness test. Data were analyzed using the Kruskal-Wallis test and the Mann-Whitney test. The extraction method used was maceration using 96% ethanol. The concentration of the extract dosage used were 0.2; 0.5; 1; 2; and 4%, with control (+) temephos and control (-). Repetitions were carried out 3 times with a sample total of 675 larvae. Observations were made for 12 and 24 hours. Preparation of granules using 2 formulas, formula 1 granules without extract and formula 2 granules with the extract. To fulfill the granule formulation criteria, the preparation was evaluated. The results showed that the concentration of 4% extract was the most effective at 98.7%, as stated by the Kruskal-Wallis test result,p-value <0.05, which means that there was an effect on the effectiveness of larvicide. The percentage of mortality of larvae given formula 2 is 100% and based on the Mann-Whitney test with value p<0.05, there is a difference between granule 1 and 2 formula. Criteria of granule including moisture content (1.72 %), angle of rest 240, flow velocity (50 gr/sec), and dispersion time (2.25 minutes). The granular formula of Musa x paradisiaca L leaves can make the application easier and hopefully can be used as effectively as synthetic larvicide in the community.
Analisa Keberhasilan Program Pemberian Obat Pencegahan Massal (POPM) Filariasis Re-TAS 1 di Kabupaten Hulu Sungai Utara
Authors: Suryatinah Yuniarti , Rahayu Nita , Sulasmi Sri , Yuana Windy Tri , Setyaningtyas Dian Eka
Published: August 2021

District of Hulu Sungai Utara conducted an additional 2 (two) rounds of Mass Drug Administration (MDA) for filariasis prevention in 2014 and 2015 that resulted in the success of the re-Transmission Assessment Survey Phase 1 (re-TAS 1) in 2016. This study was conducted to identify factors affecting the technical aspects of the aforementioned two additional rounds of MDA. This is a descriptive qualitative study, with a cross-sectional study design. The research was performed from September to November 2017. Data was collected through in-depth interviews with some executive stakeholders (health workers, cadres, community leaders, local women group) involved in the implementation of MDA for the filariasis elimination program. The result from indepth interviews shows the presence of technical factors at the execution level which supports the smooth implementation of the two additional rounds of MDA. Those factors include communication, resources, operational standard, bureaucracy, and pharmaceutical innovation. The success of the additional MDA roundswas marked by the absence of the re-TAS sample that was tested positive of Brugia Rapid™. The pharmaceutical innovation which transforms the dosage form of the medication into powdered form with some additional sweetener that was done in 2014-2015 can improve coverage of the treatment as well as the medication adherence for the early childhood population group. Changing pharmaceutical dosage forms require additional support in the form of human resources, infrastructure as well as financing
COMENTÁRIO AO ARTIGO DE CHRISTINA VITAL DA CUNHA: “IRMÃOS CONTRA O IMPÉRIO: EVANGÉLICOS DE ESQUERDA NAS ELEIÇÕES 2020 NO BRASIL”
Authors: Lehmann David
Published: August 2021

O comentário retoma dois temas do artigo de Christina Vital: a laicidade e a questão da família. Pergunta-se se as ideias dos candidatos evangélicos de esquerda têm alguma chance de avançar num público que dificilmente entende porque as igrejas deveriam ficar fora das instituições políticas (laicidade). Também aponta a ausência do tema da família no discurso desses candidatos quando não seria difícil imaginar um enfoque de esquerda sobre os problemas de violência e abandono que sofrem as mulheres e seus filhos nas camadas de baixa renda que conformam a base das igrejas. O comentário parte do pressuposto de que a opinião política dominante do público evangélico é conservadora, sobretudo enquanto há questões que tocam a sexualidade e os direitos reprodutivos, mas o autor reconhece que diante de um universo tão grande e diverso como o evangélico se deve questionar a suposição de que existe uma hegemonia absoluta de ideias conservadoras, apesar das evidências encontradas em pesquisas de opinião.
Fatores associados ao edentulismo em indivíduos com doença renal crônica em hemodiálise: um estudo transversal
Authors: De Matos Cardoso Natalia Mendes , Ruy Carneiro Natália Cristina , Silva de Castilho Lia , Souza e Silva Maria Elisa , Borges-Oliveira Ana Cristina
Published: August 2021

Introduction: Chronic kidney disease (CKD) is a progressive condition characterized by structural or functional abnormalities of the kidney. CKD may be associated with several oral alterations, such as higher prevalence rate of dental caries, periodontal disease, xerostomia, candidiasis and burning mouth. The aim of the study was to identify risk factors associated with edentulism in adults with CKD undergoing hemodialysis. Methods: A cross-sectional study was conducted with 650 individuals aged 18 to 90 years undergoing hemodialysis in southeastern Brazil. Oral clinical examination and administration of a questionnaire addressing demographic characteristics and dental history were performed. The study received approval from the Human Research Ethics Committee of UFMG. Findings: A total of 183 participants were edentulous (28.2%). Individuals with less schooling (OR= 3.99; 95% CI: 2.34-6.79), those who had not been to a dentist in the previous six months (OR = 2.49; 95% CI: 1.52-4.08), those who rated their own smile as excellent or good (OR = 2.00; 95% CI: 1.35-2.97) and those with some mucosal alteration (OR= 4.17; 95% CI: 2.83-6.13) had a greater chance of belonging to the edentulous group. Discussion: The present findings can contribute to the establishment of public health policies aimed at guiding dental care programs for individuals with chronic kidney disease that take into account the specific needs of this population. Conclusion: Edentulism was associated with low schooling, a lack of dental care in the previous six months, a positive self-perception of one’s smile and alterations in the oral mucosa.
Arte na Pedagogia
Authors: Barbosa Ana Mae
Published: August 2021

Arte na Pedagogia
Expediente
Authors: GEARTE Revista
Published: August 2021

Expediente
Viral Filtration: A Review of Current and Future Practices in Bioprocessing
Authors: Johnson Sarah , Chen Shuang , Bolton Glen , Chen Qi , Lute Scott , Fisher John , Brorson Kurt
Published: August 2021

For drug products manufactured in mammalian cells, safety assurance
practices are needed during production to assure that the final
medicinal product is safe from the potential risk of viral
contamination. Virus filters provide viral retention for a range of
viruses through robust, size-based retention mechanism. Therefore, a
viral filtration step is commonly utilized in a well-designed
recombinant therapeutic protein purification process and is a key
component in an overall strategy to minimize the risks of adventitious
and endogenous viral particles during the manufacturing of biotechnology
products. This review summarizes the history of viral filtration,
currently available viral filters and prefilters, and viral filtration
integrity test methods and study models. There is also discussion of
current understanding and gaps with an eye toward future trends and
emerging filtration technologies.
Long-term hearing performance and soft tissue outcomes of Baha@ Attract system in patients with bilateral congenital microtia in a single center
Authors: Chen Ying , Xie You-zhou , Ren Liu-Jie , Gao Na , Gu Wen-xiu , Li Chen-long , FU YAOYAO , Zhang Jun-li , Zhang Tian-yu
Published: August 2021

Abstract： Background: Baha Attract System was designed as non-skin
penetrating bone conduction implant to minimize skin complication.
However, there were insufficient studies on its long-time acoustic
outcome and safety in microtia patients with auricle reconstruction
surgeries, who have thinner retroauricular subcutaneous layer and
theoretically vulnerable skin at the implant side. Objectives: To
analysis the long-term hearing performance and soft tissue complications
of Baha@ Attract System in microtia population. Study Design & setting:
A prospective cohort study at single tertiary referral center. Patients:
Twenty Mandarin-speaking patients with congenital bilateral microtia who
were underwent Baha@ Attract implantation with or without auricle
reconstruction surgeries simultaneously. Main Outcome Measure(s):
Comparative analysis of audiological test results including hearing
thresholds and speech recognition in quiet and in noise were pre- and
post-operatively performed. subjective benefit as measured with the SSQ
Scale. Soft tissue outcomes were monitored and documented. Results: The
mean follow-up time was 36.11±3.30 months. Significant and stable
improvements in hearing threshold and speech understanding in noise and
quiet were demonstrated with aided condition. Subject evaluation
revealed high level of patients’ satisfaction with the amplification in
all the subscales. Adverse events including skin necrosis increased
after one year post-operatively. Soft tissue evolution including sin
thinning, erythema, epidermis atrophy, soft tissue atrophy, skin
necrosis was seen or once developed in most of the participants.
However, prevalence of severe soft tissue complication was not higher to
non-microtia population. Conclusions: Baha@ Attract System provides
favorable and stable hearing improvements for microtia patients.
Combining plastic surgeries with implantation will not increase the
prevalence of soft tissue complication. However, long-term soft tissue
problems should be highly aware of even after one year post
implantation. Key words: Baha Attract, microtia, hearing, soft tissue,
skin necrosis
VELOCITY MODEL OF CRUST OF AZERBAIDJAN ON DATA OF DIGITAL SEISMIC STATIONS
Authors: Етирмишли Г.Д. , Казымова С.Э.
Published: August 2021

При изучении скоростной структуры земной коры Азербайджана по сейсмологическим данным ис- пользовались в основном два подхода. Первый состоит в уточнении модели среды на основании наблюда- емых отклонений времен пробега волн от землетрясений относительно стандартного годографа. Второй основан на использовании разности времен пробега от источников до станции для групп близко располо- женных событий. Одномерные скоростные модели Р и S-волн были построены на основе одномерных моделей, пред- ложенных в работе Гасанова А.Г. Построение модели, расчет станционных поправок и перелокация со- бытий производились в программе Velest. Исследуемый объем до глубины 60 км был разбит на мелкие слои толщиной 2 км в интервале глубин 010 км и толщиной 510 км в интервале глубин 1060 км. В ходе исследования рассматривались сейсмологические данные о параметрах локальных землетрясений и вре- менах прихода P и S-волн зарегистрированных сетью телеметрических станций за период 20042011 гг. Анализировались данные 28-ми сейсмических станций Азербайджана, охватывающие всю исследуемую территорию. Для расчета трехмерного скоростного поля использовалась программа TomotetraFD. В этой програм- ме реализован классический сейсмотомографический метод для случая, когда источники и приемники находятся внутри исследуемого региона.

Two approaches were used for investigation of crust velocity structure of Azerbaijan on the basis of seismological data. The first one consists in medium model adjustment on the basis of observed deviation of travel times of waves from earthquakes relative to standard hodograph. The second is based on difference in travel times from source to station for a group of close located stations. One dimensional velocity models of P- and S-waves were constructed on the basis of one dimensional models proposed by A.G.Gasanov. Model design, calculation of stations corrections and relocationing of events 74 Геология и геофизика Юга России, 1, 2012 were performed in Velest program. Investigating volume to depth of 60 km was divided in small layers of 2 km thickness in 0-10 km interval and 5-10 km in 10-60 km interval. Seismological data about parameters of local earthquakes registered by network of telemetric stations in 2004-2011 and arrival times of P- and S-waves were used. Data of 28 seismic stations of Azerbaijan covering all the investigating territory were analyzed. Three dimensional velocity field was calculated by means of TomotetraFD program. Classical seismotomographical method for the case when sources and receivers are located within investigating region is realized in the program.
THE FITOINDICATION OF CONSEQUENCES OF 20 SEPTEMBER 2002 GLACIER KOLKA COLLAPSE – AS A TOOL FOR LONG-TERM FORECASTING OF GLACIAL CATASTROPHES IN THE VALLEY OF THE RIVER GENALDON
Authors: Комжа А.Л.
Published: August 2021

Изучение последствий гляциальных катастроф в долине р. Геналдон и прогнозирование этих ката- строф базируются, как правило, на абиотических индикаторах. Между тем, для этих целей можно исполь- зовать целый ряд биологических индикаторов (в особенности, фитоиндикаторов). В контексте геоэкологического мониторинга долины р. Геналдон нами проведен поиск фитоинди- каторов, маркирующих в ландшафте последствия схода ледника Колка 20.09.2002 г. и предшествующих гляциальных катастроф. В результате установлена возможность эффективного использования некоторых растительных сообществ, достаточно четко идентифицируемых в ландшафтах, для фитоиндикации по- следствий гляциального события 20.09.2002 г. и долгосрочного прогнозирования гляциальных катастроф в долине Геналдона. Ниже приводятся краткие итоги проведенных исследований.

Investigation of the glacial catastrophes effects in the Valley of Genaldon and prediction of these catastrophes are based generally on abiotic indicators. Meanwhile, one can also use a number of biological indicators (especially fitoindikators). In the context of Genaldon Valley geoecological monitoring we searched the fitoindikators, which mark in the landscape the consequences of the 20.09.2002 glacier Kolka fall, and earlier glacial collapses. In a result the possibility of effective usage of some plant communities, clearly identifiable in landscapes, for fitoindication of the 20.09.2002 event consequences, and long-term forecasting of glacial collapses in the Valley of Genaldon was established. The summary of the investigations performed is given below.
TO THE PROBLEM OF INVESTIGATION OF ABNORMAL APPEARANCE OF SEISMIC IMPACTS IN NEAR-SOURCE AND NEAR-FIELD ZONES OF STRONG EARTHQUAKES
Authors: Геодакян Э.Г. , Оганесян С.М. , Карапетян Дж.К.
Published: August 2021

Геологическая среда распространения волнового поля характеризуется геометрическим расхожде- нием и поглощением упругих сейсмических волн. Основными факторами, влияющими на уровень сейсми- ческого эффекта в пункте наблюдения, является геологическое строение 30ти метрового инженерного слоя грунта, наличие в нем различных включений и их мощности, а также плотность и пористость грунто- вых пород, насыщенных различными флюидами. В то же время сопоставление сейсмологических данных с геологическим строением региона при разрушительных землетрясениях 1985 г. (Мексика) и 1988 г. (Армения) показывает, что причиной наблюденных эффектов усиления сейсмического воздействия на значительных расстояниях от эпицентров, стало резонансное усиление амплитуды колебаний в верхней части разреза, мощностью несколько сотен метров. Также следует отметить, что наблюденные эффекты изменений сейсмических воздействий связаны как с интенсивностью волнового поля (геометрическая нелинейность), так и с геолого-геофизическими свойствами среды (физическая нелинейность)

Geological medium of wavefield propagation is characterized by geometrical divergence and absorption of elastic waves. The main factors influencing the level of seismic effect at the observation point are geological structure of a 30m engineering layer of soil, the presence of a variety of inclusions and their power, and the density and porosity of ground rocks saturated with different fluids. At the same time, comparison of seismic data with the geological structure of the region during the strong earthquakes in 1985 (Mexico) and 1988 (Armenia) shows that the cause of the observed effects of amplification of the seismic action at considerable distances from the epicenters, was resonant amplification of the amplitude in the upper soil part of several hundreds of meters. It should also be noted that the effects of changes of observed seismic effect are associated with both the intensity of the wave field (geometric nonlinearity), and with geological and geophysical properties of the medium (the physical nonlinearity).
GEODYNAMICS AND SEISMICITY TEREK-CASPIAN BASIN
Authors: Керимов И.А. , Гайсумов М.Я.
Published: August 2021

Рассмотрены вопросы тектоники, современной геодинамики и сейсмичности Терско-Каспийского прогиба. Характер мощных тектонических движений определил разломно-блоковое строение фундамента и нашел отражение в осадочном чехле. Данные изучения СВДЗП свидетельствуют о высокой степени современных движений сосредоточенных в определенных зонах, отождествляемых с погребенными разломами. По комплексу геолого-геофизических данных выделены разломы различной ориентировки и соответственно различных фаз тектонической активности. Проведен анализ сейсмической активности. В результате обработки и интерпретации большого объема геолого-геофизических материалов выделены участки палео- и современной геодинамической активности. В результате анализа разломно-блоковой тектоники, развития СВЗДП и современной сейсмической активности выделены зоны ВОЗ

The questions of tectonics, geodynamics and seismicity modern Terek-Caspian basin was study. Character powerful tectonic movements defined fault-block structure of the crustal surface and is reflected in the sedimentary cover. These recent crustal movements study indicate a high degree of modern vertical movements are concentrated in certain areas, which are identified with buried faults. According to the complex geological and geophysical data allocated the faults of different orientation and correspondingly different phases of tectonic activity. Analysis of seismic activity. As a result, processing and interpretation of a large amount of geological and geophysical data areas of paleo-and modern geodynamic activity. An analysis of the fault-block tectonics, development recent vertical movements and modern seismic activity, zones of possible sources of earthquakes.
HIGHLY SENSITIVE SEISMIC CONVERTER ON THE BASIS OF THE CAVITY RESONATOR OF SHF SHF
Authors: Козырев Е.Н. , Симакин А.Г.
Published: August 2021

В статье рассмотрены результаты исследования генераторов сверхвысоких частот на волнах типа Н01 и TEM (поперечная электромагнитная волна), используемых в качестве датчиков для регистрации и измерения слабых сейсмических колебаний. Приведены зависимости отдельных характеристик сейсмоприемников на основе объемных резонаторов на волнах типов Н01 и ТЕМ

In the article are examined the results of investigating the generators of superhigh frequencies on the waves of the Н01 and ТЕМ type, utilized as the sensors for the registration and the measurement of weak seismic fluctuations. The dependences of the separate characteristics of seismic receivers on the basis of cavity resonators on the Н01 and ТЕМ type waves are given
CHARACTERISTICS OF GEOPHYSICAL FIELDS ON THE ELBRUS AND KAZBEK
Authors: Заалишвили В.Б. , Невская Н.И. , Невский Л.Н. , Шемпелев А.Г.
Published: August 2021

В статье рассмотрены особенности геологического строения Эльбруса и Казбека. Одной из особен- ностей поля силы тяжести Кавказа является наличие для районов Приэльбрусья и Чегемского нагорья самых минимальных значений в Большекавказском регионе. Относительно положительные значения гра- витационного поля Казбекского района, определяются приповерхностным слоем с избыточной плотно- стью 0,15х103 кгм3 верхняя и нижняя границы которого находятся на глубинах порядка 0,5 и 4,5 км. Зона Главного хребта Центрального Кавказа является в региональном плане областью пониженных значений магнитного поля, которое осложнено локальными знакопеременными аномалиями.

In the article the features of geological structure of Elbrus and Kazbek are examined. One of the features of the gravity fields of the Caucasus is the availability for areas of Elbrus and Chegem Highlands most minimum values in the big Caucasus region. The positive values of the gravitational field of the Kazbek district, are determined by the surface layer with excessive densities of 0,15х103 кgм3 the top and bottom borders are at depths of about 0.5 and 4.5 km. Area of the main ridge of the Central Caucasus has at the regional level the lower values of the magnetic field, which is complicated by alternating local anomalies
AGGREGATION OF THE ORE MINERALS GEOPHYSICAL PROSPECTING METHODS IN THE MOUNTAIN REGIONS
Authors: Келоев Т.А. , Гудиева И.Н.
Published: August 2021

В статье обоснованы геофизические исследования рудоконтролирующих факторов и эндогенного оруденения в горных регионах. В следствие труднодоступности горных районов основное место в комплексе занимают мобильные методы изучения аномалий естественного происхождения

Geophysical studies of ore-controlling factors and endogenous mineralization in the mountain regions are substantiated in the article. In the consequence of the difficult accessibility of mountain regions the mobile methods of studying the anomalies of natural origin occupy basic place in the complex
RESULTS OF GEOPHYSICAL INVESTIGATIONS ON ADYGEYA PROFILE
Authors: Шемпелев А.Г. , Кухмазов С.У. , Заалишвили В.Б. , Невский Л.Н.
Published: August 2021

В последние годы несколькими организациями были выполнены геофизические исследования различными методами в западной части Центрального Кавказа. Вдоль Адыгейского профиля (Дагомыс-Абадзехская-Гиагинская) впервые получена комплексная геофизическая характеристика глубинного разреза земной коры вкрест всей структуры Большого Кавказа. Рассматриваются материалы МТЗ, МОВЗ и гравимагнитных съёмок. Предполагается, что структура Большого Кавказа, как часть Альпийского коллизонного пояса, возникла при наползании Скифской эпигерцинской плиты на консолидированную кору одной из закавказских микроплит

In recent years, several organizations have been implemented geophysical surveys in the western part of the Central Caucasus using a variety of methods. Along the Adygeya profile (Dagomys-Abadzekhskaya- Giaginskaia) were received a comprehensive geophysical characteristics of deep crustal section across the entire structure of the Greater Caucasus. Examines material МТZ, IGAD and gravimagnetsurvey. The structure of the Greater Caucasus, as part of the Alpine collision belt, appeared with creeping of the Scythian plate on one of the Caucasuss consolidated crust microplate
LANDSLIDES OF THE SOUTHERN CAUCASUS
Authors: Бондырев И.В. , Церетели Э.Д. , Али У. , Заалишвили В.Б.
Published: August 2021

Среди перечня стихийных катастроф важное место занимают катастрофы, спровоцированные оползнево-гравитационными процессами. Опасность оползневых процессов проявляется не только в ущербе, который они причиняют (а это более 200500 млн. США ежегодно), но и в их широком, почти повсеместном распространении.

Disasters caused by landslide- gravitational processes took an important place among natural disasters. Landslide processes hazard appears not only in caused damage (over 200500 mil. USA annually) but also in their wide and practically general distribution