bluuebunny/crossref_metadata_2025 huggingface dataset:
Biological features of blood lymphocytes of the primary patients with endometrial cancer
Authors: Domina Emiliia , Hrinchenko Olha
Published: May 2021

The aim: to examine the radiosensitivity of chromosomes of T-lymphocytes in the blood of primary patients with endometrial cancer depending on the radiation dose. It was expected that the investigations would reveal a cytogenetic parameter as a predictor of radiosensitivity in non-malignant cells of patients exposed to curative irradiation.

Materials and methods. Blood samples from 20 primary patients and 30 conditionally healthy donors were examined. Peripheral blood T-lymphocytes culture test system with metaphase chromosome aberration analysis was used. X-ray test-irradiation was performed at G0-stage of the cell cycle in the dose range of 0.5–3.0 Gy.

Results. It was shown that the spontaneous level of chromosome aberrations in lymphocytes of primary patients before anti-tumour therapy is 7,82±0,33 aberrations/100 metaphases. This is more than 2-fold higher than the upper limit of average population index and approximately 6-fold higher than the data of own control. In our study during X-ray irradiation of cells cultures of patients, it was found for the first time that the total frequency of radiation-induced chromosome aberrations obeys the classical linear quadratic dose dependence with a predominance of linear component values; the frequency of radiation markers – also linear quadratic dose dependence, but with a predominance of quadratic component.

Conclusions. High specificity of T-lymphocyte chromosomes to exposure to ionizing radiation as well as strict dependence of chromosome aberration yield on exposure dose justify their use as predictors of radiosensitivity of healthy cells from the tumour environment. The revealed dependences of induction of chromosomal damage in T-lymphocytes of patients with endometrial cancer prove the need for a personalized approach to plan the course of radiation therapy
Efeitos do Trabalho em Turnos e Coping em Profissionais de Enfermagem Hospitalar
Authors:   Universidade Federal do Rio Grande do Sul, Antoniolli Liliana , Cócaro de Souza Sônia Beatriz , Barcellos Teixeira Macedo Andreia , Dal Pai Daiane , Müller de Magalhães Ana Maria , Bosi de Souza Magnago Tânia Solange
Published: May 2021

Introdução: Respostas de coping podem influenciar na adaptação dos profissionais ao trabalho em turnos, contribuindo para manutenção da saúde e qualidade de vida. Assim, objetivou-se verificar a associação entre coping e efeitos do trabalho em turnos sobre a saúde dos profissionais de enfermagem. Materiais e Métodos: Estudo transversal, realizado com 124 profissionais de enfermagem em um hospital universitário, no período de agosto a novembro de 2014. Utilizou-se o questionário Coping com o Trabalho por Turnos, instrumentos para avaliação de efeitos do trabalho em turnos na saúde e avaliação da qualidade de vida. Dados analisados estatisticamente, considerando-se significância de 0,05. Resultados: Observou-se associação inversa entre efeitos do trabalho em turnos e escore total do coping (p=0,003). Domínios do coping apresentaram correlações diretas com domínios de qualidade de vida (p<0,05). Das participantes, 46 (37%) profissionais apresentavam efeitos do trabalho em turnos na saúde. Discussão: O uso do coping contribui com menor ocorrência dos efeitos negativos do trabalho em turnos sobre a saúde, dentre estes, funções cognitivas, sono, hábitos alimentares e gástricos, e estresse. Ainda, podendo cooperar para manutenção do bem estar psíquico e físico, adaptação laboral, e melhor qualidade de vida. Conclusões: O conhecimento da relação entre coping e efeitos do trabalho em turnos na saúde pode auxiliar na identificação de meios para promover melhores condições de trabalho, preservando o bem-estar físico e psíquico, e a saúde do profissional de enfermagem.
Necesidades de cuidado dentro del hospital del cuidador de personas con cancer
Authors:   Instituto Nacional do Câncer, Rio de Janeiro, Brasil, Rodrigues Lins Ana Luiza , Toledo de Mendonça Erica , Ricardo Moreira Tiago , Almeida de Matos Renata , Andrade João Vitor , Cássia de Freitas Martins Thalyta , Lopes do Carmo Mônica Maria
Published: May 2021

Introducción: La existencia de un paciente con cáncer en el seno de la familia implica desafíos y lleva a una necesidad de reorganización de la dinámica familiar para la prestación de cuidados, lo que puede provocar la negligencia de los auto-cuidados del cuidador, además de las necesidades de segundarización dentro del hospital, durante la hospitalización del ente enfermo. Objetivo: comprender qué cuidados los familiares cuidadores de personas con cáncer gustarían recibir en el hospital. Materiales y Métodos: estudio cualitativo, realizado en un hospital de cáncer de Brasil, con 14 familiares, en 2019. Las entrevistas fueron cerradas en el momento en que existía la saturación de datos y analizadas por la técnica de Análisis de Contenido. La investigación cumple con los aspectos éticos. Resultados: la primera categoría reveló el acogimiento, las competencias de actitud del equipo, la asistencia psicológica y la casa de apoyo como medidas importantes que la institución ofrece a los cuidadores. La segunda categoría mostró qué cuidados los familiares gustarían recibir, y los testimonios revelaron la transferencia del cuidado de sí mismo a los demás, y aún las demandas de cuidado físico, espiritual y psicológico. Discusión: es evidente que existe un acercamiento entre lo que el cuidador espera de la institución estudiada como cuidado de sí mismo, con la asistencia ofrecida. Conclusiones: el estudio señala la necesidad de planificar estrategias de apoyo a los familiares cuidadores en el entorno hospitalario, además de grupos de apoyo interdisciplinario y apoyo psicológico continuo.
Competencia para cuidar y Soporte social en cuidadores de Norte de Santander: Perspectiva comparativa
Authors:   Universidad Francisco de Paula Santander, Gonzalez Escobar Dianne Sofia , Vega Angarita Olga Marina
Published: May 2021

Introducción: La forma en que los cuidadores afrontan las demandas de cuidado de los enfermos crónicos, depende de la competencia para brindar el cuidado y de la percepción de apoyo de las fuentes cercanas a él. El objetivo del estudio fue establecer la relación entre la competencia para el cuidado y el soporte social de los cuidadores familiares de personas con enfermedad crónica en el departamento Norte de Santander. Materiales y Método: Estudio cuantitativo, de tipo correlacional de corte trasversal. Conto con la participación de 352 cuidadores, ubicados en la ciudad de Cúcuta, Ocaña y Pamplona, municipios de Norte de Santander, a quienes les fue aplicado los instrumentos: GCPC- UN-D, GCPC-UN-CPC y SSCI. Resultados: La mayor parte de los cuidadores de los municipios de Cúcuta y Pamplona, poseen un nivel medio de competencia para el cuidado (50.6% y 49.4% respectivamente), mientras en el municipio de Ocaña, la mayoría de cuidadores mostraron un alto nivel de competencia para el cuidado (89.3%). En el soporte social de los cuidadores se evidencian diferencias significativas entre los municipios del departamento, encontrándose poco satisfechos con el soporte recibido los cuidadores de Cúcuta y Pamplona, y satisfechos los cuidadores de la ciudad de Ocaña. Discusión: En los cuidadores tanto la competencia para el cuidado como la percepción de soporte social varían en las diferentes regiones del departamento. Conclusión: Se subraya la necesidad de abordar las dificultades que experimentan los cuidadores en lo relativo a la competencia para el desempeño eficaz del cuidado y el soporte social.
A Large Software System Test Engineering Practices
Authors: Bandyopadhyay Biswadeb
Published: May 2021

The following Paper describes the experiences of a test engineering team, which had worked with a large software product development and support activity. This team has studied the existing software product, available test tools, test environment, with an objective of analyzing existing
testing processes and methodologies for this large software product. The Paper discusses a number of initiatives and recommendations made by this test engineering group aimed at increasing the testing efficiency, optimizing the test suites, measuring and improving effectiveness of test cases
and the quantifiable benefits and process improvements, that can derived from such initiatives. This activity was undertaken as part of a test engineering initiative to bring in place a set of innovative test engineering practices as potential business value drivers.
Trusted Location Selection in Vehicular ad-hoc Network
Authors: Soni Sonam
Published: May 2021

VANET gives the advantage to enhance road safety and assure less or no traffic accidents. However, false messages can result in serious conditions like collision. This paper proposed a new, trust based technique for location selection in VANET. In the paper presents a trust based
location selection scheme has two phases computation of direct and indirect trust. However, evaluation of direct trust system using infrastructure (RSU) and trusted authority (TA) and evaluation of indirect trust uses watchdog approach. Results show that the proposed scheme suitable for the
actual situation of VANET.
A Computer Vision based Framework for Detecting Potholes on Asphalt-Road using Machine Learning Approach
Authors: Das Abhishek , Saha Sourav
Published: May 2021

This paper proposes a Pothole Detection Framework which may assist the pedestrian in avoiding potholes on the roads by giving prior warnings. The basic idea of this framework is to detect the pothole on asphalt road by analyzing the image of the road-surface. This proposed framework
combines image processing techniques with machine learning methods and primarily explores edges, Histogram of Gradients and Local Binary Patterns of an image frame for extracting features to detect the presence of potholes on the road surface. The experimental results indicate promising potential
of the proposed framework for detection of potholes on asphalt-road.
Li-Fi Synchronicity towards 5 G: concepts, challenges and opportunities
Authors: Sharma Shilpi
Published: May 2021

It is quite frustrating when the moderate speed of system prompts restricts availability and long handling hours while utilizing remote web either at home system or coffeehouse or airplane terminal or going after data transfer capacity at a meeting. As more clients are tapped in
with their gadgets, the stopped up wireless transmissions make it hard to hook on a dependable sign. Radio wave is by all accounts completely abused and other range should also be investigated. For this reason, fibre optics have been utilized to send information through LED light. D-Light
can deliver information rates speedier than 10 super bits for each second, which is far quicker than normal broadband association.
Validation of an endoscopic flavectomy training model
Authors: KULCHESKI ÁLYNSON LAROCCA , STIEVEN-FILHO EDMAR , NUNES CAROLLINE POPOVICZ , MILCENT PAUL ANDRÉ ALAIN , DAU LEONARDO , I-GRAELLS XAVIER SOLER
Published: May 2021

ABSTRACT Objective: to validate a lumbar spine endoscopic flavectomy simulator using the construct method and to assess the acceptability of the simulator in medical education. Methods: thirty medical students and ten video-assisted surgery experienced orthopedists performed an endoscopic flavectomy procedure in the simulator. Time, look-downs, lost instruments, respect for the stipulated edge of the ligamentum flavum, regularity of the incision, GOALS checklist (Global Operative Assessment of Laparoscopic Skills), and responses to the Likert Scale adapted for this study were analyzed. Results: all variables differed between groups. Procedure time was shorter in the physician group (p < 0.001). Look-downs and instrument losses were seven times greater among students than physicians. Half of the students respected the designated incision limits, compared to 80% of the physicians. In the student group, about 30% of the incisions were regular, compared to 100% in the physician group (p < 0.001). The physicians performed better in all GOALS checklist domains. All the physicians and more than 96% of the students considered the activity enjoyable, and approximately 90% believed that the model was realistic and could contribute to medical education. Conclusions: the simulator could differentiate the groups’ experience level, indicating construct validity, and both groups reported high acceptability.
Hotter, Longer and More Frequent Heatwaves: An Observational Study for the Brazilian City of Campinas, SP
Authors: Oliveira Daniela Souza de , Costa Paula Dornhofer Paro , Bezerra Luiza Marchezan , Avila Ana Maria Heuminski de , Faria Eliana Cotta de
Published: May 2021

Abstract Worldwide there is accumulated evidence of heatwave intensification due to climate change. Regional differences in the effects of heatwaves require local studies to implement public mitigation and adaptation strategies. This work analyzes and characterizes heatwaves’ occurrence for the city of Campinas, Brazil, through an observational study from 1956 to 2018. The definition of heatwaves adopted requires that the maximum and minimum daily temperatures be above the daily limits derived from climate normal 1961-1990. The annual and seasonal metrics of the number, frequency, and heatwaves’ duration showed significant and positive trends, except in winter. We found that the longest, the more intense, and the most frequent events occurred in the last 20 years and that a significant change in trend occurred at the beginning of the 1980s. Lastly, we performed an exploratory study of intra-urban variability, comparing heatwave metrics between two different weather stations that are 30 km apart in the city of Campinas. We found similar metrics patterns for the two weather stations, with more prolonged and more frequent heatwave events for the region's station with a higher rate of urban land occupation.
Histopatological effects of bleaching and disease on the coral Siderastrea stellata from coastal reefs of Brazil
Authors: Sassi Cristiane F. Costa , Farias Gabriel M. de , Vasconcelos Amanda de S. , Macedo Rebeca S. de , França Jéssica P. de S. , Sassi Roberto
Published: May 2021

ABSTRACT Histological analysis of bleached samples of Siderastrea stellata Verrill, 1868, with white plague disease and with alteration in the color pattern, revealed drastic tissue and cellular disturbances, such as lysis of the external epithelium, hyperplasia of gastrodermis, apoptosis of epithelial cells and zooxanthellae, and degradation of mesenteric filaments and reproductive cells. Fungal hyphae, diatoms, and cyanobacteria were present in diseased samples and colonies with alteration in the color pattern. Furthermore, bleached and diseased samples showed significant reductions in the number of zooxanthellae per 100 µm2 of gastrodermis and significant reductions in the diameters and volumes of stage V oocytes. We found that bleaching events, diseases, and colonies with alteration in the color pattern promoted degradation of reproductive cells, resulting in the consequent interruption of the reproduction of the coral S. stellata, which is one of the most common Brazilian coral species. The implications of these indirect effects of bleaching, disease, and changes in coral color patterns in the population dynamics of Brazilian reefs are discussed.
PARENTING PRACTICES AND THE CHILD'S EATING BEHAVIOR
Authors: Santos Kelly de Freitas , Reis Mayra Alves dos , Romano Márcia Christina Caetano
Published: May 2021

ABSTRACT Objective: to investigate the association between the parenting practices and the child's eating behavior. Method: a cross-sectional study, conducted with 368 children aged from one to five years old, registered in the Family Health Strategy units of the urban area of the municipality of Divinópolis-MG. An anthropometric assessment was performed to classify the children's nutritional status. Information was collected from January to September 2019 referring to demographic and socioeconomic data, as well as to lifestyle, health status, diabetes, parenting practices, and children's eating behavior. The child's eating behavior was assessed by means of a food frequency questionnaire, where the daily consumption of ultra-processed foods was estimated. Multiple linear regression was used to assess the association between parenting practices and the child's eating behavior, with a significance level of 5%. Results: greater consumption of ultra-processed foods was identified when the parents used physical force (p<0.018), reward for eating (p<0.002), and food restriction (p<0.011) practices. A negative association with the consumption of ultra-processed foods was evidenced when the parents provided guidance for healthy eating (p<0.006), authoritative monitoring (p<0.017), and positive reinforcement of the children's behavior that is considered adequate (p<0.046). Conclusion: the results of this study evidenced that the parenting practices were associated with the children's eating behavior. Therefore, research studies on the determinants of this behavior are recommended.
SIMULATION IN NURSING: PRODUCTION OF THE KNOWLEDGE OF THE GRADUATE COURSES IN BRAZIL FROM 2011 TO 2020
Authors: Assis Maurício da Silva de , Nascimento Juliana da Silva Garcia , Nascimento Kleiton Gonçalves do , Torres Gabriel Andrés Segura , Pedersoli Cesar Eduardo , Dalri Maria Celia Barcellos
Published: May 2021

ABSTRACT Objective: to synthesize the production of knowledge on simulation in Nursing generated by the Nursing graduate programs in Brazil between January 2011 and February 2020. Method: a documentary research study, which adopted as primary source the official documents of the Coordination for the Improvement of Higher Level personnel, conducted by means of an integrative literature review from October 2019 to February 2020, with quantitative analysis of the data. Results: initially, 68 studies were identified, 40 of them comprising the final sample. The following categories stood out: purpose of the studies; types of simulation; Health Care level; variables analyzed regarding the effectiveness of the simulation; themes addressed; comparison of the effectiveness of simulation with that of other teaching strategies, and weaknesses and potentialities of simulation. The scientific research of the Brazilian graduate courses prioritized the analysis of the effectiveness of simulation in the development of knowledge, satisfaction and confidence, in an off-site or virtual teaching environment, aimed both at hospital care and at primary care, mainly in Neonatology and Pediatrics, with the participants' anxiety as main weakness; and satisfaction, knowledge, critical thinking, safety, confidence and the ability to articulate theory and practice as potentialities. Conclusion: this study contributes to research, teaching and care in Nursing, for enabling the identification of the scientific production setting on simulation, which supports new research studies, with a focus on objectives and settings not yet explored. Simulation is indicated as an effective strategy for the development of cognitive, psychomotor and attitudinal skills in Nursing.
MOBILE SIMULATION: SCIENTIFIC CONTRIBUTIONS FOR THE HEALTH AREA
Authors: Silva Cristiane Costa Reis da , Fernandes Maria Isabel Domingues , Baptista Rui Carlos Negrão , Silva Rosana Maria de Oliveira , Malfussi Luciana Bihain Hagemann de , Silva Gilberto Tadeu Reis da
Published: May 2021

ABSTRACT Objective: to identify and analyze in the literature the use of the mobile simulation strategy for health professionals and for the community. Method: a scoping review based on the procedures recommended by the Joanna Briggs Institute. The search databases were the following: PubMed, CINAHL via EBSCO, Scopus, LILACS, Portugal's Open Access Scientific Repository and CAPES Dissertations Database. The guiding question was the following: What contributions of the mobile simulation have been identified and assessed in the training processes of health professionals and of the community? There was no limitation regarding publication year, and nine studies were selected. Results: 2011 had the highest number of publications on this theme, most of them coming from the United States. It was evidenced that the mobile simulation contributed to the training of health professionals and community-dwelling individuals, favored the development of the professionals' clinical competencies, and proved to be an effective tool to take training to remote zones. Conclusion: mobile simulation is a modality that contributes to the development of the simulated practice regarding the active teaching method; however, it is still little explored, and expanding the perspectives of its implementation emerges as a challenge.
CREENCIAS DE LOS ESTUDIANTES DEL MÁSTER DE SECUNDARIA EN ESPAÑA-PORTUGAL
Authors: Molina-Torres María-Pilar
Published: May 2021

Resumen El objetivo general de este estudio es analizar la realidad curricular y las opiniones de los estudiantes acerca de los métodos de enseñanza que conocen durante su formación profesional en el Máster de Profesorado de Educación Secundaria de la Universidad de Córdoba (España) y la Universidad de Oporto (Portugal). La metodología implementada nos ha permitido identificar mediante un cuestionario tipo encuesta las concepciones del alumnado sobre las metodologías y las estrategias didácticas que piensan serían más adecuadas para su futura práctica profesional y formación docente. Los resultados de la investigación señalan que los estudiantes desconocen los modelos didácticos a emplear en sus clases. Por último, este trabajo supuso una oportunidad para sondear las creencias que el alumnado tiene acerca de la excesiva teorización de las materias.
O MANIFESTO DOS EDUCADORES DE 1959 REVISITADO: EVENTO, NARRATIVAS E DISCURSOS
Authors: Bontempi Jr. Bruno
Published: May 2021

Resumo Trata-se de análise histórica do manifesto de educadores “Mais uma vez convocados: manifesto ao povo e ao governo” (1959), divulgado em resposta à irrupção de um substitutivo ao projeto de Lei de Diretrizes e Bases da Educação. Examina os alicerces de sua memória, interrogando as razões e os efeitos da predominante explicação por meio de suas relações com o Manifesto dos Pioneiros e a Campanha em Defesa da Escola Pública. Reconstrói eventos, agentes e significados, compreendendo-os como ação coletiva e coordenada de intelectuais para fins políticos determinados. Conclui-se realçando o manifesto em sua especificidade e historicidade, aparando equívocos historiográficos resultantes de repetições sem lastro e abordagens que produziram lacunas em sua compreensão como evento singular.
INCLUSÃO ESCOLAR: EFEITOS DO PLANO NACIONAL DE EDUCAÇÃO NOS PLANOS MUNICIPAIS
Authors: Rigo Neusete Machado , Oliveira Morgana Maciel de
Published: May 2021

Resumo Este artigo apresenta uma análise sobre as possibilidades de uma política pública nacional desdobrar--se em políticas municipais efetivas. Discute a operacionalização da meta 4 do Plano Nacional de Educação nos planos municipais de educação em relação à formação continuada de professores para a inclusão escolar por abordagem qualitativa, analisando o conteúdo dos planos municipais de educação. Os resultados da pesquisa mostram que os municípios propõem, majoritariamente, formação aos professores do atendimento educacional especializado, em detrimento daqueles que atuam nas salas regulares, concluindo-se que os planos, em geral, distanciam-se da construção de sistemas educacionais inclusivos e seguem uma concepção de educação especial centrada no atendimento educacional especializado.
On the Cluster Admission Problem for Cloud Computing
Authors: Dierks Ludwig , Kash Ian , Seuken Sven
Published: May 2021

Cloud computing providers face the problem of matching heterogeneous customer workloads to resources that will serve them. This is particularly challenging if customers, who are already running a job on a cluster, scale their resource usage up and down over time. The provider therefore has to continuously decide whether she can add additional workloads to a given cluster or if doing so would impact existing workloads’ ability to scale. Currently, this is often done using simple threshold policies to reserve large parts of each cluster, which leads to low efficiency (i.e., low average utilization of the cluster). We propose more sophisticated policies for controlling admission to a cluster and demonstrate that they significantly increase cluster utilization. We first introduce the cluster admission problem and formalize it as a constrained Partially Observable Markov Decision Process (POMDP). As it is infeasible to solve the POMDP optimally, we then systematically design admission policies that estimate moments of each workload’s distribution of future resource usage. Via extensive simulations grounded in a trace from Microsoft Azure, we show that our admission policies lead to a substantial improvement over the simple threshold policy. We then show that substantial further gains are possible if high-quality information is available about arriving workloads. Based on this, we propose an information elicitation approach to incentivize users to provide this information and simulate its effects.
Game Plan: What AI can do for Football, and What Football can do for AI
Authors: Tuyls Karl , Omidshafiei Shayegan , Muller Paul , Wang Zhe , Connor Jerome , Hennes Daniel , Graham Ian , Spearman William , Waskett Tim , Steel Dafydd , Luc Pauline , Recasens Adria , Galashov Alexandre , Thornton Gregory , Elie Romuald , Sprechmann Pablo , Moreno Pol , Cao Kris , Garnelo Marta , Dutta Praneet , Valko Michal , Heess Nicolas , Bridgland Alex , Pérolat Julien , De Vylder Bart , Eslami S. M. Ali , Rowland Mark , Jaegle Andrew , Munos Remi , Back Trevor , Ahamed Razia , Bouton Simon , Beauguerlange Nathalie , Broshear Jackson , Graepel Thore , Hassabis Demis
Published: May 2021

The rapid progress in artificial intelligence (AI) and machine learning has opened unprecedented analytics possibilities in various team and individual sports, including baseball, basketball, and tennis. More recently, AI techniques have been applied to football, due to a huge increase in data collection by professional teams, increased computational power, and advances in machine learning, with the goal of better addressing new scientific challenges involved in the analysis of both individual players’ and coordinated teams’ behaviors. The research challenges associated with predictive and prescriptive football analytics require new developments and progress at the intersection of statistical learning, game theory, and computer vision. In this paper, we provide an overarching perspective highlighting how the combination of these fields, in particular, forms a unique microcosm for AI research, while offering mutual benefits for professional teams, spectators, and broadcasters in the years to come. We illustrate that this duality makes football analytics a game changer of tremendous value, in terms of not only changing the game of football itself, but also in terms of what this domain can mean for the field of AI. We review the state-of-the-art and exemplify the types of analysis enabled by combining the aforementioned fields, including illustrative examples of counterfactual analysis using predictive models, and the combination of game-theoretic analysis of penalty kicks with statistical learning of player attributes. We conclude by highlighting envisioned downstream impacts, including possibilities for extensions to other sports (real and virtual).
Cheapest-to-Deliver Pricing, Optimal MBS Securitization, and Market Quality
Authors: Huh Yesol , Kim You Suk
Published: May 2021

We study optimal securitization and its impact on market quality when the secondary market structure leads to cheapest-to-deliver pricing in the context of agency mortgage-backed securities (MBS). A majority of MBS are traded in the to-be-announced (TBA) market, which concentrates trading of heterogeneous MBS into a few liquid TBA contracts but induces adverse selection. We find that lenders segregate loans of like values into separate pools and tend to trade low-value MBS in the TBA market and high-value MBS outside the TBA market. We then present a model of optimal securitization for agency MBS. Lenders do not internalize the negative impact of such pooling and trading strategies on TBA market quality and thus create too many high-value MBS, which leads to more heterogeneity in MBS values, more adverse selection, and lower TBA liquidity. Lastly, we provide empirical evidence consistent with model predictions on how MBS pooling changes with trading costs and underlying loan value dispersion and how pooling practices affect MBS heterogeneity and TBA market adverse selection.
Resiliencia contra la pandemia de covid-19 en comunidades indígenas kichwa en la Amazonía ecuatoriana
Authors: Sirén Anders , Uzendoski Michael , Swanson Tod , Negrete Iván Jácome , Gualinga Emil Sirén , Tapia Andrés , Machoa Alex Dahua , Tanguila Aymé , Santi Eugenia , Machoa Dionicio , Andi Dixon , Santi Daniel
Published: May 2021

Entre marzo – agosto de 2020, hubo un contagio muy generalizado de covid-19 en las comunidades indígenas Kichwa en la Amazonía ecuatoriana.  Mostramos que el pico de contagio ya ha pasado y la mortalidad total ha sido notablemente baja. El pueblo Kichwa identifica su éxito en resistir la pandemia al uso generalizado de plantas medicinales.
Ambient air quality data reported at Sasol Secunda monitoring stations during COVID-19 lockdown – Mpumalanga, South Africa
Authors: Venter Andrew , De Vos Sandra
Published: May 2021

Various local and international research has been published on the effects of COVID-19 lockdown on ambient air quality. In most cases, a reduction in ambient NOx and PM concentrations have been observed with varying changes in ambient SO2 levels. Secunda, located in the Highveld Priority Area in Mpumalanga, South Africa is known for its large industrial facilities utilising coal as primary feedstock. The towns of Secunda and eMbalenhle provide the majority of the workforce to Sasol and has therefore been the focus of this study. The ambient air quality in the Secunda region was assessed due to the changes in human behaviour during lockdown, familiarity with the Sasol facility and the strategic locations of ambient air quality stations.Results show a clear decrease in ambient CO, NO2 and PM concentrations, especially during the first two weeks of lockdown. Only subtle changes were observed for ambient H2S and SO2 pollutant concentrations at the ambient monitoring stations. An increasing trend in all ambient species was observed towards the end and post lockdown, in contrast to declining ambient temperatures with the onset of winter. This is also contrary to the reduction in emissions from the factory that conducted annual maintenance in the month following lockdown (phase shutdown). This article concludes that human behaviour has a material local ambient impact on CO, NO2 and PM pollutant species, while H2S concentration profiles are more directly related to the industrial complex’s levels of activity. Ambient SO2 trends did not show a similar correlation with the facility’s activities (as H2S), but a stronger correlation was observed with the diverse local and regional sources in close proximity to Secunda and eMbalenhle. The influence of better dispersion especially on a local scale, brought about by more effective emission heights, is considered material. Moreover, meteorological factors, on local air quality, has been shown to be a material contributor to observed ambient air quality levels in the study domain
KARACİĞER TRANSPLANTASYONUNDA MİKROKİMERİZM OLMADAN TOLERANS MÜMKÜN MÜDÜR?
Authors: ÇAĞ Murat , ÖZDEMİR Sevda Yeşim
Published: May 2021

Amaç

Karaciğer transplantasyonu sonrası tolerans kavramı

son yıllarda giderek popülarite kazanmaktadır. Bu çalışmada

amacımız çok özenli parametrelerle seçilmiş

yaklaşık on yıllık bir seride düşük doz immünosupressif

kullanan bir grupta toleransın varlığını CD3+

hücrelerde mikrokimerizmin yokluğu ile kanıtlamaya

çalışmaktır.

Gereç ve Yöntem

Mikrokimerizm yokluğunu araştırma yöntemi; retrospektif

olarak donör kanlarından cross match yapılarak

DNA izolasyonunun ardından, mikrosatellit markerlarının

PCR ile amplifikasyonu ve dönör ve alıcı allellerinin

karşılaştırılması ilkesine dayanıyordu.

Bulgular

Postoperatif takiplerinde organ reddi ya da buna bağlı

komplikasyonları olmayan alkole bağlı sirozu olan

12 hastadan bir izogrup oluşturuldu. Bu hastalar immunsüpresif

olarak takrolimus ve mikofenolat mofetil

kullanıyordu ve ilaç kan düzeyleri 5 ng/l yani kabul

edilebilir sınırın altında idi. Çalışmamızda hiçbir hastamızda

kimerizm gözlemlemedik.

Sonuç

Biyokimyasal stabiliteyi koruyan mikrokimerizmin

yokluğu yani transplantasyona tolerans olması durumunda

immunsupressif tedavilerin kesilebilir olmasının

düşünülebilirliği gündeme gelmektedir.Böylelikle

immünsüpressif tedavilerin yan etkileri azalacak ve

hastalar böbrek yetmezliği, metabolik bozukluklar,

diyabet ve kanserlerin artmış riskinden korunacak,

dolayısı ile yaşam kalitesi artmış ve transplantasyon

sonrası kullanılan ilaçların ülke ekonomisine yükü

azalmış olacaktır.
Loading Tn5 Enzyme with sci-protocol Oligonucleotides v1
Authors: Mulqueen Ryan , Fields Andy , Adey Andrew
Published: May 2021

Loading of Tn5 enzyme for sci-ATAC and s3 protocols.
Некоторые проблемы теории и философии права
Authors: Захарцев С.И.
Published: May 2021

Книга посвящена рассмотрению отдельных актуальных проблем теории и философии права. В ней исследуются предмет философии права, роль диалектического метода в ее познании, содержание права, правосознание и его деформация, проблемы правовой науки и пути их решения, правовой прогресс и др. Выдвигаются новые идеи и предложения. Особое обращается внимание на новые вызовы человечеству в виде незащищенности от информационного насилия и распространения биомедицинских экспериментов. Для научных работников в области философии и теории права, преподавателей, аспирантов, студентов, а также всех, кто интересуется проблемами права и философии права.
Введение в акмеологию учителя
Authors: Собянин Ф.И.
Published: May 2021

Монография посвящена новому направлению психолого-педагогического знания – акмеологии и построена на примере исследования профессии учителя физической культуры. Это одна из первых монографий по данной тематике – первое издание в России вышло еще в 1998 году. Она включает введение, 5 глав, заключение, приложения и список литературы. В первой главе «Акмеология – новая область знания» - даются основные определения акмеологии, ее объект и предмет исследования, определения профессиональной пригодности и готовности учителя, а также его педагогического мастерства. Высказывается принципиальная позиция автора к пониманию путей достижения вершин в профессии учителя на основе профессиональной пригодности в противоположность компетентностному подходу. Вторая глава «Сфера профессиональной деятельности учителя физической культуры» раскрывает физическую культуру с позиции теории В.М. Выдрина, как специфический вид культуры общества, показывает ее некоторые тенденции, особенности физкультурного образования. Третья глава «Деятельность учителя физической культуры» включает описание структуры и содержания деятельности учителя физической культуры, условия и особенности его труда, характеристику основных этапов его «профессиональной жизни», оценку профессиональной деятельности. Четвертая глава «Особенности личности учителя физической культуры» посвящена моделированию личности учителя, эмпирическому изучению профессиональной пригодности к педагогической деятельности, характеристике профессиональных заболеваний, авторской методике диагностики профпригодности к деятельности учителя физической культуры. Заключительная пятая глава «Авторская система деятельности учителя» кратко дает понятие о сущности авторской системы деятельности педагога и очерчивает проблемы ее созидания в реальности. Книга имеет определенное теоретическое, методическое и практическое значение для психолого-педагогического цикла наук и может служить основой для продолжения подобных исследований по другим педагогическим специальностям. Она получает отклик и используется в процессе преподавания на факультетах физической культуры и педагогических факультетах в вузах. Монография предлагается студентам, магистрантам, аспирантам, преподавателям педагогических колледжей, вузов, ученых, исследующих проблемы образования, физической культуры, личности и деятельности учителей. Книга выдержала три издания, была опубликована в России и Молдавии.
Evaluation of the influence of friction in a multi-leaf spring on the working conditions of a truck driver
Authors: Hryciów Zdzisław , Krasoń Wiesław , Wysocki Józef
Published: May 2021

This article presents a simulation study of the suspension system in a vehicle that weighs approximately 12 tons (class N2). The authors have tested the influence of experimentally determined values of friction coefficients on the energy dissipated in the multi-leaf spring. The study was carried out using finite element analysis with LS-DYNA software. A nonlinear vibration model of the complete spring was developed, including the variable friction forces between the leafs. The model takes into account the sprung and unsprung mass of the chassis. Numerical tests were carried out using three different coefficients of friction (determined experimentally) for a selected speed of the car. Random realizations of the road micro-profile (type A, B, C) recommended by ISO 8608 were used. The results of the tests were presented in the form of acceleration curves in the vertical direction, comparative plots of daily vibration exposure A(8) and vibration transmission coefficient (T), and the distributions of RMS acceleration in frequency of one-third octave bands. This data was used to assess the quality of the vibration isolation system between the front suspension of the vehicle and the driver’s seat.
Análisis del hashtag #MeQuedoEnCasa: la conversación digital por twitter® ante la emergencia producida por la covid-19
Authors: Vela Delfa Cristina , Cantamutto Lucia , Núñez-Cansado Marian
Published: May 2021

La crisis sanitaria de la covid-19 vino acompañada de medidas de aislamiento, entre las que se encontraba el confinamiento domiciliario, que provocaron múltiples reacciones en las redes sociales. El objetivo de este artículo consiste en analizar la conversación digital observada en Twitter®, en torno al hashtag #MeQuedoEnCasa, en el periodo comprendido entre el 20 y el 27 de marzo de 2020. El estudio parte de una metodología mixta, en la que se combinan técnicas de análisis del social media mining con estrategias cualitativas propias del análisis lingüístico. Desde el punto de vista teórico, nos apoyamos en conceptos de las teorías del encuadre y de la valoración. Los resultados apuntan al enmarque positivo del confinamiento, a través de rasgos semióticos de distinto nivel: léxico, semántico y pragmático. Las cuentas más influyentes inclinaron su producción discursiva hacia la polaridad positiva. El análisis empírico permite concluir que el encuadre discursivo de esta conversación digital combina dos ejes semánticos (colectividad y salud), dos ejes enunciativos (aquí y ahora) y un eje emocional, lo que implica que hashtags como #MeQuedoEnCasa funcionan como señas de identidad social, como marcas de anclaje enunciativo y como instrumentos para fomentar la responsabilidad del individuo desde valores positivos.
La construcción de un corpus computarizado de errores escritos con textos de estudiantes universitarios en Colombia
Authors: Pardo Rodríguez María Victoria
Published: May 2021

El presente artículo describe las etapas de una investigación doctoral en la construcción de un corpus computacional a partir de textos escritos por estudiantes de inglés como lengua extranjera. La compilación de los datos se realizó conforme a los procedimientos de la lingüística de corpus computacional (McEnery & Hardie, 2011). El corpus permitió determinar los errores más frecuentes de los estudiantes con el fin de conocer el nivel de interlengua y mejorar las prácticas docentes para el aprendizaje.
Análisis del léxico de las emociones: una aproximación desde la disponibilidad léxica y la teoría de los grafos léxicos
Authors: Blanco Correa Óscar Elías , Salcedo Lagos Pedro , Kotz Grabole Gabriela Emilce
Published: May 2021

El presente trabajo aborda el léxico de las emociones en el contexto estudiantil. Se cree inicialmente que los estudiantes apelan a diferentes lexías para expresar emociones y que estas corresponden a determinados centros de interés. Se utilizó la metodología de la disponibilidad léxica combinada con la teoría de los grafos, al aplicarse una encuesta a 119 estudiantes de dos facultades de la Universidad de Concepción, Chile. Los resultados muestran que los estudiantes verbalizan sus emociones y que estas se relacionan con determinados centros de interés, lo que sugiere una mayor promoción de las mismas en las aulas.
Some Teachers and Students’ Perceptions about Pedagogical Strategies in the English Classes
Authors: Arias Rodríguez Gladis Leonor
Published: May 2021

This study analyzed the perceptions about the strategies applied in 8th and 9th grades at a private high school during the first semester of 2019. Data were gathered through a semi-structured interview and a survey. The findings show that the school uses a guide book as the main academic material; however, students and teachers would like to use other materials that foster communication. The research evidences the importance of listening to teachers and students in order to find out aspects that help to improve EFL teaching and learning.
El Colombiano frente al fenómeno abstencionista en la elección de constituyentes: una mirada desde el análisis crítico del discurso de Teun van Dijk
Authors: Pineda Arboleda Juan Fernando
Published: May 2021

A partir de las bases del Análisis Crítico del Discurso (ACD) el presente artículo examina la respuesta de El Colombiano frente al fenómeno abstencionista en la elección de constituyentes para la formulación de la nueva carta magna en 1991. Para ello se realizó la revisión de dos niveles básicos del ACD en el discurso periodístico (contextual y lingüístico), en donde se reconoce la tendencia oficialista del diario y su intención por simular neutralidad. Este texto constituye un aporte al análisis de las narrativas periodísticas predominantes en Colombia, las cuales no suelen ser estudiadas con suficiencia.
Argumentação jurídica e argumentação linguística: quando a língua em uso revela preconceitos
Authors: Valerio Daiane , Forneck Kári Lúcia
Published: May 2021

Com base na teoria da argumentação na língua, este trabalho teve como proposta investigar a argumentação jurídica, sob o viés da concepção da argumentação linguística, em sentenças de crimes cometidos contra mulheres, para evidenciar se havia indícios de possíveis resquícios de enunciação de caráter preconceituoso. Foram requisitadas as dez últimas sentenças julgadas de cada ano (2014-2018), de uma comarca do Rio Grande do Sul (Brasil). Através da análise dos encadeamentos argumentativos, pôde-se chegar a uma interface entre a argumentação linguística e jurídica, evidenciando que há enunciados e enunciadores que ainda acabam propagando discursos preconceituosos contra a mulher.
Las modulaciones antipoéticas en tres poetas colombianos: Óscar Hernández, Jaime Jaramillo Panesso y Aníbal Arias
Authors: Molina Morales Guillermo
Published: May 2021

Este artículo estudia los trabajos de Óscar Hernández (1925-2017), Jaime Jaramillo Panesso (1938) y Aníbal Arias (1948). En Las contadas palabras, Hernández utiliza elementos antipoéticos para desarrollar una retórica populista que mantiene la elevación del poeta. En Antipoemas de un malevo, Jaramillo Panesso se sumerge en ambientes urbanos y marginales con vocación documental y algunos logros basados en la ambivalencia. En Motivos ajenos a la voluntad, Arias transmite la violencia en la propia forma poética mediante fragmentos broncos que aparentan poca elaboración literaria. En conjunto, estas obras generan un cambio en la línea antipoética de la literatura colombiana.
A arte transformada em palavras
Authors: Pugas Panichi Edina Regina
Published: May 2021

Este artigo analisa a construção textual do Pedro Nava, com base na crítica genética e estilística. Serão analisados os documentos de processo utilizados e os princípios que direcionam a busca pela composição estética. A mistura de elementos artísticos e literários na formulação da escrita do autor, bem como a utilização de desenhos na construção dos personagens, resultam na concretização de um pensamento marcadamente visual, uma vez que a condensação da visualidade passa por um processo de expansão na transformação de imagens em palavras, resultando num estilo raro do ponto de vista plástico e imagético.
Un precursor desconocido de la sintaxis estructural: H. Tiktin, por Eugenio Coseriu
Authors: Molina Mejía Jorge Mauricio , Betancur Serna Maribel
Published: May 2021

Se ofrece una traducción inédita de uno de los trabajos de Eugenio Coseriu (1980). Se trata de un capítulo historiográfico que busca escudriñar los esquemas de representación sintáctica de las oraciones, denominados stemmas. Se puede, así, vislumbrar todo un trabajo de rastreo histórico que busca remitirse hasta los antecesores de este tipo de modelos sintácticos, atribuidos a Tesnière (1934) y a algunos estructuralistas norteamericanos como Bloomfield, Nida y Hockett a partir de 1940. Coseriu presentaría entonces a Heimann Hariton Tiktin, un filólogo alemán, quién habría propuesto en 1883 un tipo de representación fundamentado en un modelo de dependencias.
Actores de la memoria colectiva del golpe de Estado de 1976 y de la crisis de 2001 en Argentina: rol de la memoria cultural, la memoria comunicativa, la pertenencia generacional y la ideología política
Authors: Bermejo Federico , Muller Felipe , Cevasco Jazmín
Published: May 2021

La memoria colectiva ha sido definida como el conjunto de recuerdos que comparte una comunidad, el cual incide en la formación de su identidad. Sus fuentes incluyen la memoria cultural, compuesta por artefactos culturales, y la memoria comunicativa, trasmitida mediante las interacciones cotidianas. El objetivo de este estudio fue examinar el rol de la fuente, la pertenencia generacional (recuerdos vividos y distantes) y la ideología (derecha e izquierda) en el recuerdo de los actores del golpe de Estado de 1976 y de la crisis económica de 2001 en Argentina. Ciento treinta y dos participantes completaron una tarea de recuerdo libre acerca de uno de estos dos eventos. Los resultados indicaron que aquellos participantes que tenían memoria cultural, recuerdos distantes e ideología de izquierda recordaban una mayor proporción de actores. Además, con relación a los actores específicos, cuando los participantes tenían memoria cultural, se encontraron diferencias entre grupos generacionales e ideológicos.