bluuebunny/crossref_metadata_2025 huggingface dataset:
Box-Behnken Designed Eluxadoline Loaded Chitosan Nanoparticles for the Treatment of Irritable Bowel Syndrome
Authors: Dhere Manisha , Jain Deepak
Published: November 2024

A recently approved drug eluxadoline shows promise as a treatment and management for irritable bowel syndrome-D. However, because of its low water solubility, which results in a low dissolution rate and oral bioavailability, its applications have been limited. The current study aims to cure irritable bowel syndrome by developing chitosan nanoparticles containing eluxadoline. Box-Behnken Design Expert software was used to optimize the chitosan nanoparticles loaded with eluxadoline that had been developed. Sodium tripolyphosphate was used as a cross-linking agent in the ionic gelation process to developed the Eluxadoline-loaded chitosan nanoparticles. The effects of chitosan concentration (X1), sodium tripolyphosphate concentration (X2), and sodium tripolyphosphate volume (X3) on particle size, PDI, zeta potential and entrapment efficacy from nanoparticles were investigated. The results revealed that entrapment efficiency was highest at low level of chitosan concentration, high level of Sodium tripolyphosphate concentration and low levels of Sodium tripolyphosphate volume. Based on the particle size (300.4), PDI (0.305), zeta potential (41.2mV), and entrapment efficacy (76.89%), the resulting formulation was optimized. The efficiency of the drug release from optimised formulation was studied in vitro by using a dialysis bag diffusion technique in buffer condition 6.8 pH intestinal conditions. The optimized formulation showed a sustained release behaviour with maximum drug release 80.23%. Accordingly, the results proved that the developed chitosan-based polymeric nanoparticles can act as a potential approach for the effective delivery of eluxadoline through oral administration for irritable bowel syndrome diarrhoea treatment.
Stock performance analysis of selected companies in pharmaceutical industry
Authors: Jain Vidhi , Singh Gunjan
Published: November 2024

India's reputation as the world's leading supplier of generic drugs, coupled with its renowned affordability in vaccines and generic medications, highlights its pharmaceutical industry's prominence. Ranked third in pharmaceutical manufacturing by volume, this sector has experienced impressive growth, boasting a Compound Annual Growth Rate (CAGR) of 9.43% over the past nine years. Integral components of India's medicinal landscape include general medicines, over-the-counter specifics, bulk medicines, vaccines, contract exploration and manufacturing, bio-similar, and biologics. This paper investigates the stock performance of four prominent pharmaceutical entities traded on the National Stock Exchange (NSE) capital market: Lupin Limited, Cipla Limited, Dr. Reddy's Laboratories Limited, and Torrent Pharmaceuticals Limited. Utilizing historical stock price data from April 2013 to December 2019 sourced from Yahoo Finance, the analysis employs various statistical methodologies such as descriptive statistics, the money flow index (MFI), and the beta index. Additionally, forecasting is conducted using the Automatic Regression Integrated Moving Average (ARIMA) model2. Findings indicate that Dr Reddy's laboratory shares demonstrated superior performance compared to their counterparts, with Lupin Limited, Torrent Pharmaceuticals Limited, and Cipla Limited following suit. These insights furnish investors with valuable information for making well-informed decisions regarding stock holding, purchasing, or divestment, grounded in specific signals derived from the statistical indices utilized in the analysis. The primary objective of this study is to assess the profitability of the Indian pharmaceutical industry, offering insights into the financial efficacy of companies for both investors and society at large. By forecasting the economic status of these entities for specific periods, the research endeavours to assist management in pinpointing areas necessitating resource optimization and improvement.
The Role of Organizational Justice in Enhancing Employee Engagement and Well-being
Authors: Karthick K K
Published: November 2024

The effect of justice in organizations on staff engagement and well-being is examined in this research. The study used two questionnaires and discovered a favourable relationship between staff engagement, well-being, and organizational justice characteristics. Three aspects of organizational justice were also found by the research: distributive justice, interactional justice, and procedural justice. The impact of justice in the organization on staff engagement and happiness is being investigated empirically for the first time with this research. Managers should enhance fairness in the organization, provide rewards equally, and guarantee equitable promotion procedures for more senior positions, according to the research’s recommendations.
Effects of Phuong Dong Dai Trang tablets on intestinal motility in experimental animals
Authors: Tung Tran Thanh , Van Anh Pham Thi , Duong Dau Thuy
Published: November 2024

Phuong Dong Dai Trang tablets (PDDT) prepared from several medicinal plants, including Hedychium coronarium, Coix lacryma-jobi, Dioscorea persimilis, Cynara Scolymus L., Paeonia lactiflora, Glochidion eriocarpum, are intended to treat gastrointestinal function disorders. This study was carried out to evaluate the effects of PDDT on intestinal motility in vivo and ex vivo. Swiss mice were divided into four groups that were given orally 0.9% sodium chloride, Duspatalin (mebeverine) 80 mg/kg b.w./day, PDDT 1080 mg/kg b.w./day and PDDT 3240 mg/kg/b.w./day, respectively for 5 days. The activated charcoal movements were measured 20 minutes and 40 minutes after all mice were fed with 0.2 ml of 10% activated charcoal. New Zealand White rabbit’s isolated intestinal segments were divided into two groups with two concentrations of PDDT 1350 mg/100 ml Tyrode’s solution and 2025 mg/100 ml Tyrode’s solution, respectively. The intestine’s contractile frequency and amplitude were recorded. Our results showed that both doses of PDDT reduced the intestinal motility in mice and reduced the contractile frequency and amplitude in the rabbit’s isolated intestinal segments.
Preliminary evidence on the diagnostic value of apolipoprotein B and A-I in peripheral artery disease among Vietnamese patients with diabetes
Authors: Ha Nguyen Manh , Lan Nguyen Thi Ho , Binh Pham Thai , Phuc Vu Minh , Kien Hoang Van , Quynh Tran Thi Nhu , Quynh Nguyen Thi Nhu , Giang Nguyen Thi , Thu Nguyen Thi , Thu Nguyen Thi Minh , Mai Nguyen Ngoc , Hoa Nguyen Thi Ngoc , Huong Dinh Thi Thu
Published: November 2024

To evaluate the value of apolipoprotein A-I, B, and the apoB/AI ratio in the diagnostic of peripheral artery disease among patients with diabetes, we conducted a cross-sectional study of which they underwent clinical evaluation, standardized Doppler ultrasound and blood test. Area under the Receiver Operating Characteristic curve method was employed to estimate the discriminatory ability of apolipoprotein A-I, apolipoprotein B, and the ApoB/A-I ratio. A total of 159 patients were included. ApoA-I, ApoB, and the ApoB/A-I ratio show statistically significant associations with most clinical and Doppler ultrasound characteristics of PAD. In Pearson’s correlation analysis, apolipoproteins showed a stronger correlation with ABI than the traditional lipid profile. The AUROC was 0.714 (95%CI: 0.635 - 0.794); 0.300 (95%CI: 0.219 – 0.380) and 0.604 (95%CI: 0.516 – 0.692) for apoB/A-I ratio; apoAI and apoB, respectively. The probability apoB/A-I cutoff of 0.666 had a sensitivity of 0.682 and a specificity of 0.662. Apolipoprotein AI and Apolipoprotein B are tests with considerable potential in diagnosing peripheral arterial disease in patients of type 2 diabetes mellitus patients. Further studies are needed with larger sample sizes, and employing imaging diagnostic modalities with higher reliability as the gold standard (MSCT angiography).
Preoperative clinical, subclinical characteristics and nutritional status of gastric cancer patients at Vietnam National Cancer Hospital
Authors: Dang Nguyen Van , Luong Nguyen Hong
Published: November 2024

Gastric cancer ranked fourth for incidence and mortality of all cancers in Vietnam. Clinical symptoms in the early stages are often nonspecific. Patients may have epigastric pain, anorexia or weight loss. Gastroscopy combined with biopsy is a clinical test that helps diagnose gastric cancer. Endoscopic ultrasound, computed tomography of the abdomen and chest are important examinations to assess the stage of the disease. Gastric cancer patients had a high rate of malnutrition, and preoperative nutritional management represents a challenge. Cross-sectional descriptive research was conducted on 88 gastric cancer patients aged over 18 years old to describe preoperative clinical, subclinical characteristics and nutritional status at National Cancer Hospital from January to December 2023. Epigastric pain was the most common clinical symptom with 92%, ulceration type was the most common macroscopic type with 63.9%, poorly differentiated adenocarcinoma was the most common histopathological type with 43.2%, 53.4% of anemic patients. The preoperative malnutrition rate according to albumin, BMI and PG-SGA were 34.1%, 29.5% and 55.7% respectively. Research shows that some preoperative clinical and paraclinical characteristics were very typical of a gastric cancer patient. A very high rate of malnutrition was found in gastric patients before surgery.
Factors associated with depression, anxiety, and stress among medical college students
Authors: Phuong Nguyen Viet , Thong Nguyen Quang , Ve Pham Van , Hieu Vo Thi , Tu Le Thi Cam , Tha Le Kim , Hang Tran Thi Thuy
Published: November 2024

Academic pressure, stress, and associated factors are pervasive throughout education. Lately, depression, anxiety, and stress emerged as alarming mental health issues among health science students. A cross-sectional descriptive study was conducted among 2,064 students at Can Tho Medical College to determine the prevalence of depression, anxiety, and stress, along with associated factors. Data were collected online using the DASS-21 questionnaire via Google Forms. The prevalence rates of depression, anxiety, and stress among college students were 52.4%, 73.1%, and 58.8%, respectively. Factors associated with these conditions included gender, body satisfaction, daily smartphone use, primary smartphone activities, satisfaction with academic performance, ease of forming friendships, and presence of close friends. As depression, anxiety, and stress were significant concerns among medical college students, educators should implement screening programs and develop strategies to improve and enhance students’ mental health.
Knowledge and attitude about HPV vaccine among the 4th year female nursing students at Hanoi Medical University
Authors: Dang Nguyen Van , Phuong Nguyen Thi Nam
Published: November 2024

Vaccines against HPV have been found to be the most effective known method in preventing cervical cancer. University students and young adults have a high prevalence of genital HPV infection because of their risky sexual behavior, lack of knowledge of HPV infection, HPV vaccination and misconception about susceptibility. A cross-sectional descriptive research was conducted to assess knowledge, attitudes about HPV vaccine among 120 fourth - year female nursing students at Hanoi Medical University in 2023. The majority (75.8%) of students had good knowledge. Students who had never been in a relationship had worse knowledge of HPV vaccine than other students who have been or had been in a relationship. Students with income had better knowledge of HPV vaccine than students with no income (p < 0.05). The majority (66.7%) of students had a positive attitude With Kinh people had more positive attitude towards HPV vaccine (p < 0.05). Research showed that most of the 4th year female nursing students at Hanoi Medical University had good knowledge and a positive attitude towards the HPV vaccine. There was a significant association between knowledge of HPV and factors such as income, and relationship status. There was a significant association between attitudes and ethnicity.
Life quality after orchiectomy of the bone metastatic prostate cancer patient
Authors: Linh Can Phuong , Lien Bui Bich , Binh Nguyen Thi
Published: November 2024

Prostate cancer (PC) with bone metastasis has many clinical symptoms that very much affected to the patient’s quality of life (QoL). Improving cancer patient’s QoL is a mission for the health care professional workers. The study using questionaires SF-36 and UCLA-PCI-SF- a simple and common methods to evaluate the progress of orchiectomy treatment for bone metastases PC to assess the QoL and prostate-specific functions before and after orchiectomy. Clinical manifestations such as urinary tract, sexual function symptoms, anxiety, bone pain and insomnia affected the HRQoL (health related quality of life) of 53 participated patients were quite high from 69.8% up to 90.6%. After 1 month of orchiectomy, these symptoms were markedly reduced to less than 20%; Anxiety and Insomnia still affected 50.9% and 47.1% of study participant, respectively. HRQoL of 53 PC patients with bone metastasis after orchiectomy was remarkably improved. All domains of SF-36 and UCLA-PCI-SF after orchiectomy were statistically significantly increased with p-value < 0.05, except sexual bother.
ICSI and conventional IVF, which one should be prefered for cases of pre-implantation genetic testing?
Authors: Van Nguyen Thi Cam , Hanh Truong Van , Trang Nguyen Thi Nhu , Hue Tran Tran , Quan Khuat Huu , Lan Le Thi Phuong , Tho Vu Thi , Lien Tran Thi Kim
Published: November 2024

Ever since its implementation in 1992, the intra-cytoplasmic sperm injection (ICSI) technique has been hailed as a game-changer for enhancing the outcomes of in vitro fertilization (IVF) treatment in cases of infertility due to male factors. However, ICSI was later widely applied to cases of infertility not due to male factors without evidence proving its effectiveness. According to the 2022 report of the European IVF Monitoring Council (EIM), the rate of fertilization cases using ICSI method accounts for 70% of IVF cases in European countries, meanwhile the conventional IVF method accounts for only 30% and this rate has remained stable from 2006 until recently. The question is whether cases of infertility not due to male factors that are indicated for pre-implantation genetic testing (PGT) should be fertilized and create embryos using ICSI or conventional IVF to minimize invasiveness and reduce costs while still ensuring the accuracy of the test results.
Intrathyroidal parathyroid cyst presenting with recurrent kidney stones: A case report
Authors: Thao Do Thu , Huong Nguyen Thi Thanh
Published: November 2024

Parathyroid cysts are rare and can be the cause of persistent hypercalcemia leading to kidney stones. The aim of this article is to present a case presenting to the hospital with recurrent kidney stones and incidentally found hypercalcemia. From there, we discovered a cystic lesion in the thyroid gland. Combining ultrasound and cyst fluid aspiration to measure the concentration of parathyroid hormone in the fluid helped us confirm that the cystic lesion belonged to the parathyroid gland. The patient underwent surgery to remove the cyst and the blood calcium and parathyroid hormone levels returned to normal after surgery.
Air pollution and its effect on upper respiratory tract infections: A scoping review from 2010 to 2019
Authors: Mai Bui Thi , Trang Nguyen Thi Huyen , Tam Tran Van , Trang Nguyen Thu , Trang Nguyen Thi Ha , Quan Pham Hong , Phuong Vu Thu , Van Hoang Thi Hong , Diep Nguyen Ngoc , Dat Le Minh
Published: November 2024

Air pollution is a significant global health concern, linked to numerous severe health outcomes, particularly respiratory infections. However, the effects of air pollution components on upper respiratory tract infections (URTI) remain limited. This study aims to synthesize the impact of air pollution on URTI from 2010 to 2019 to provide a basis for effective public health interventions. A total of 23 studies were included in the analysis, with results showing that pollutants such as PM10, PM2.5, NO2, SO2, and O3 were closely linked to URTI, particularly in children. PM10 and PM10 were identified as having the greatest impact. These findings affirm the need for further research to develop effective pollution control measures, thereby reducing the burden of upper respiratory tract infections.
K A E L : PENDEKATAN STRATEGIS MERANCANG SUKSES MELALUI KNOWLEDGE CONVERSION
Authors: Setiyo Anggraeni, S.E., M.Si., Ak., CA, ACPA Dr. Fadjar
Published: November 2024

Buku ini membahas tentang konsep holistik bagi sebuah kepemimpinan yang bisa menjadi rujukan siapapun dan merepresentasikan organisasi apapun. Anda akan mendapatkan berbagai inspirasi mengenai bagaimana kepemimpinan yang kaffah, yang akan membawa organisasi Anda tetap aman, bertahan lama, dan selalu ‘damai’. Anda juga akan mendapatkan contoh-contoh praktik terbaik dari perusahaan-perusahaan terkenal, sebagai inspirasi.
高雄豆皮文藝咖啡館「勞動藝術」的實踐與論述分析
Authors: 高俊宏 高俊宏
Published: November 2024

創立於高雄豆皮文藝咖啡館（以下簡稱豆皮），在1999年～2014年營運期間的策展與現場藝術實踐，深刻連結了勞動的議題。2002年，豆皮負責人劉秋兒拋出了「如何在豆皮勞動藝術」的探問，並且隨後展開了為期兩年、總計六十檔次的「勞動藝術」實驗，以不設限參與者背景與創作內容的方式，探討勞動與藝術之間的關係，也影響到了後續豆皮將勞動視為重要的藝術實踐的方向。本文以2002年到2004年豆皮「勞動藝術」的實踐與相關的論述建構為主，進一步探討勞動與藝術的關係。在論述的取徑上，首先梳理高雄地區勞動與勞工藝術的發展脈絡。其次，檢視豆皮「勞動藝術」的實踐與論述過程所勾勒出來的勞動美學問題。最後則探討「勞動」的議題在現今臺灣當代藝術領域裡，被以什麼樣的角度延續與關注。

 

The Dogpig Art Café (thereinafter abbreviated as “Dogpig”), established in Kaohsiung, was deeply intertwined with issues surrounding labor during curatorial practices and on-site artistic operations from 1999 to 2014. In 2002, Chiu-Er Liu (Leo Liu), the proprietor of Dogpig, initiated an exploration of “Labor Art at Dogpig” and subsequently embarked on a two-year, 60-session experiment in “labor art.” This experiment, open to participants of diverse backgrounds and creative content, aimed to investigate the relationship between labor and art. It significantly influenced Dogpig’s subsequent direction in considering labor as a crucial aspect of artistic practice. This article primarily focuses on the period from 2002 to 2004, delving into Dogpig’s “labor art” practice and associated discourse, further exploring the connection between labor and art. Methodologically, the study begins by presenting the development context of labor and labor art in Kaohsiung. It then examines the issues of labor aesthetics outlined in Dogpig’s “labor art” practice and discourse. Finally, it explores how the topic of “labor” continues to be pursued and addressed in contemporary Taiwanese art.

 
Improving Fairness and Quality in Master's Thesis Assessment in Norwegian Higher Education
Authors: Toorani Mohsen
Published: November 2024

Assessment of master's theses is a pivotal aspect of higher education, significantly influencing students' academic success and future career opportunities. In Norway, discussions on fairness, objectivity, and the integrity of thesis evaluations have highlighted challenges in ensuring impartial assessment practices, especially as universities are legally mandated to maintain transparency and impartiality. This paper examines factors that may affect the objectivity of thesis evaluations in the Norwegian context, drawing on research and case studies to highlight challenges and propose solutions. Addressing these issues is essential for upholding the credibility and fairness of higher education. By implementing strategies such as standardized assessment criteria, comprehensive examiner training, public defenses, and technology-driven approaches, Norwegian universities have the potential to set a global standard for equitable thesis evaluations. The insights and recommendations presented aim to guide policymakers, educators, and academic institutions in enhancing assessment practices to ensure fairer outcomes for all students.
Students' Visualisations of Programming Concepts: An Exploratory Analysis
Authors: Gonzalez Rolando , Klevgaard Trond , Raaen Kjetil
Published: November 2024

This study explores the intuitive visualisations of code created by novice programming students with the aim of uncovering how these reflect their understanding of fundamental programming concepts. Through a thematic analysis of student drawings, this exploratory research identifies common themes and categorises different modes of visual expression. The findings reveal great variations in how students can visualise code, and suggest that drawings can serve as an effective tool for both diagnosing student misconceptions and supporting their learning of programming. This study highlights the potential of incorporating visual exercises into programming education to improve concept comprehension.
Students' perceptions toward essential functionalities and qualities of peer code assessment tools
Authors: Bayat Esfandani Somayeh , Aalberg Trond
Published: November 2024

Peer code assessment (PCA) empowers computer science students, enhancing their learning and equipping them with practical skills for industry work. However, instructors often face a scarcity of well-designed tools customized for the learning environment. Additionally, there is a knowledge gap concerning the latest generation of peer assessment tools. So, the question is, how could a PCA tool be designed to support students’ programming learning experience? A case study was conducted using the PeerGrade tool, employing interviews and observation as data generation methods to answer this question. Research aimed to identify features that enhance student learning and uncover essential qualities of peer code assessment tools from students’ perspectives. Informants considered inline comments, general comments, rubrics, threads, and Code editor functionalities essential. They also highlighted the importance of utilizing a customized, user-friendly tool with a step-by-step process. The Self-Regulated Learning conceptual theory has been used as a theoretical lens. Based on SRL, it has been found that implementing identified tool qualities and features will improve the learning experience by increasing students’ motivation and enabling them to follow their learning strategies. The findings can be used as a design principle for developing peer code assessment tools.
Manufacturing a water turffity measuring equipment using the AB209 module sensor based on the ATMega328 microcontroller
Authors: Supardi I Wayan , Rupiasih N Y , Putra A A Gede Mahendra , Djlantik A A Andreas Putra Prawira
Published: November 2024

The development of electronic technology in the era of globalization is very rapid. Utilizing this technology as a means to monitor water clarity, especially the condition of the water, whether it is clean or there are other materials mixed with the water (turbid), to find out optimal water conditions, optimal monitoring is needed. This research will create a system that can detect water turbidity. The tool consists of a Turbidity Sensor Module AB209 sensor, ADC, and ATMega328 microcontroller. The AB209 Turbidity Sensor Module functions to detect water turbidity. The function of the ADC is to change the amount of electrical voltage resulting from the AB209 Turbidity Sensor Module into a digital quantity which is then transmitted to the ATMega328 microcontroller to be processed into a digital display on the LCD. The results of the research are that a water turbidity measurement tool can be made with a good level of accuracy, namely 99.98%.
Abordaje diagnostico y terapeutico no farmacologico, trastorno obsesivo compulsivo en adultos. Revision sistemática
Authors: Aburto Gutiérrez René Alfonso , Pineda Gea Fernanda , Téllez Ramos Carlos Manuel , Pastorino María Sol
Published: November 2024

El presente artículo tiene como finalidad sintetizar evidencia del abordaje diagnóstico y terapéutico no farmacológico en adultos con Trastorno Obsesivo Compulsivo (TOC) por medio de la revisión sistemática, incluyendo 9 reportes de caso, a través de MEDLINE , PUBMED, Google académico, Scielo, repositorios institucionales, tesauros: “Trastorno Obsesivo Compulsivo AND Adulto NOT Niños”. Utilizando criterios de inclusión: Artículos científicos publicados entre 1990- 2023, publicados en español e inglés. Resultados: 9 artículos incluidos (nueve pacientes) publicados en idioma español, ocho publicados en España en edad promedio 29.6 años, 68% de los casos con rangos de 20.8 a 38.4 años, cinco pacientes en segunda década de vida al momento de la terapia y tres en la tercera década. Edad media de inicio de los síntomas 21.12 años, inicio de sus síntomas relacionado a un evento vital estresante, sexo femenino el mayor afectado. Prevaleció el Patrón de pensamientos intrusivos. La psicoterapia combinada con técnicas de aceptación y compromiso fue eficaz en eliminar la rigidez psicológica, frecuencia de una vez a la semana con duración entre 45 a 60 minutos, una duración promedio de 23.3 semanas, con rango de 8 semanas a 48 semanas, depende de la severidad de sus síntomas. Conclusiones: pensamientos intrusivos y sexo femenino aspectos prevalentes, afecta a población joven, la terapia psicológica es efectiva, pacientes presentan mejoría de los síntomas obsesivos compulsivos incluso llegar a niveles subclínicos, la terapia cognitivo-conductual fue la mejor dirigida por un terapeuta, con sesiones semanales de una hora, cara a cara, de 8 a 43 semanas de duración.
Divertículo de meckel en adultos nicaragüenses. Reporte de dos casos y revisión de la literatura
Authors: González Bermúdez José Arnoldo , Pineda Gea Fernanda
Published: November 2024

Los casos descritos discuten la prevalencia de esta entidad clínica simulando un abdomen agudo quirúrgico en hombres adultos y compara el abordaje del divertículo de Meckel sintomático y asintomático.Métodos: El presente reporte de casos se informó utilizando las directrices internacionales que pautan los aspectos de redacción y publicación de un reporte de caso quirúrgico, mencionadas en la guía SCARE (Surgical CAse REport,2020)Presentación de caso: Pacientes masculinos de 31(caso 1) y 19 años (caso 2) respectivamente, que acuden a la unidad con abdomen agudo quirúrgico en los que se diagnostica divertículo de Meckel manera incidental (caso 1) concomitante con apendicitis aguda y sintomático (caso 2) complicado por inflamación, se observó una localización en el lado antimesentérico del íleon, más o menos 80 cm respecto a la válvula ileocecal, con longitud que oscilo entre 2(caso 1) a 10mm (caso 2).Se realiza diverticulectomía, mediante la técnica de recepción en cuña con anastomosis primaria (caso1) y recepción intestinal con aproximadamente 5cm de margen del divertículo con anastomosis termino-terminal en dos planos (caso 2) el abordaje fue exitoso en ambos pacientes.Conclusión: El diagnóstico del divertículo de Meckel complicado en adultos es difícil debido a que las características clínicas en pacientes que presentan complicaciones son inespecíficas y no se distingue clínicamente de la apendicitis, la laparotomía exploratoria parece ser una conducta quirúrgica idónea en casos de abdomen agudo quirúrgico con diagnóstico incierto.
Integrales dobles en el cálculo de la densidad de circulación de fluidos en un campo vectorial
Authors: Rodríguez Díaz Jonny Ever , Rivera González Elmer Misael , Altamirano Vásquez Freddy Josué , Herrera Castrillo Cliffor Jerry
Published: November 2024

El presente artículo tiene como objetivo analizar las aplicaciones de integrales dobles en el cálculo de la densidad de circulación de fluidos en un campo vectorial. Se aplicó el enfoque cualitativo, así mismo, se utilizó el diseño documental por ser un estudio descriptivo, en el cual se analizan conceptos básicos de integrales, campos vectoriales, fluidos, volumen de sólidos, caudal volumétrico, propiedades y tipos de evaluaciones educativas que forman parte de la columna vertebral de este trabajo. La recolección de datos fue mediante la observación de videos en la plataforma de YouTube, entrevistas a maestros universitarios, libros de textos y artículos de revista relacionados con el tema de integrales dobles, campos vectoriales y fluidos. Así mismo, para el análisis de la información fue necesario la triangulación de teorías, tomando en cuenta los diferentes puntos de vista de los investigadores con respecto al tema con el fin de llegar a una conclusión y darle solución a los dos problemas inéditos planteados a través del análisis de diferentes variables físicas y matemáticas, los cuales están relacionados con la interdisciplinariedad de cálculo integral, cálculo vectorial y mecánica de fluido. Para el análisis de resultados fue necesario la resolución de dos problemas para poner en práctica todo lo analizado y descrito en el referente teórico y dar así cumplimiento a los objetivos del trabajo.
21 claves para organizar los datos de investigación. Guía práctica de gestión de datos.
Authors: Feria Basurto Lourdes
Published: November 2024

Las 21 claves de este libro están concebidas para que las y los lectores aprendan a aprovechar algunas de las mejores estrategias para el manejo adecuado de todo tipo de datos en favor de su investigación. Al revisar esta guía conocerán los componentes básicos para organizar sus archivos, datos crudos, datos procesados, lecturas digitales, diversos componentes de software, bitácoras y otros elementos desde la primera investigación que realice.
Componentes de produção e nutrição foliar em mandioca sob adubação orgânica e mineral
Authors: Andrade Luana Ribeiro de , Silva Alinne da , Costa Niedja Bezerra , Andrade Jailma Ribeiro de , Leonel Maria Rita de Andrade , Maia Júnior Sebastião de Oliveira , Catunda Paulo Henrique Aragão , Corrêa Thaís Roseli , Figueiredo Fábio Afonso Mazzei Moura de Assis , Rodrigues Antônia Alice Costa , Ferraz Tiago Massi
Published: November 2024

A mandioca é um alimento de importância social no Maranhão, pois compõe a base da alimentação da população. A produtividade média da cultura no estado é considerada baixa, inferior a 8,6 t ha-1. O desafio é, portanto, aumentar a produtividade da cultura por meio do manejo da adubação. Os objetivos foram determinar a dose de fertilizante orgânico que promove a maior produtividade de mandioca, validar a dose de fertilizante mineral que está sendo utilizada na região, e avaliar os efeitos da combinação entre os fertilizantes orgânico e mineral nos componentes relacionados à produção e nutrição foliar. O experimento foi conduzido em delineamento de blocos ao acaso, arranjados em esquema fatorial 2 × 5, com quatro repetições. Os fatores foram duas combinações de adubação mineral (com e sem NPK) e cinco doses de esterco bovino (0, 2,5, 5,0, 7,5 e 10,0 t ha-1). Os resultados indicaram que as doses de fertilizante mineral NPK utilizada para a região resultou em aumento na produtividade da mandioca, confirmando a hipótese de que a recomendação de NPK pode ser adotada para a região. As doses superiores a 4,5 t ha-1 de esterco bovino podem gerar desequilíbrios nutricionais, refletindo em menores teores de nitrogênio e fósforo nas folhas. Foi possível concluir que a aplicação combinada de fertilizantes, dentro das doses recomendadas, otimiza a produtividade da mandioca e pode orientar práticas agrícolas sustentáveis para a garantir a segurança alimentar na região do Maranhão.
Research on Low-carbon City Construction Based on the Theory of Social and Technological Transformation
Authors: Guo Yuhui , Su Lin
Published: November 2024

In order to cope with global climate change, solve the resource and energy crisis, alleviate the deterioration of the ecological environment, implement China's emission reduction commitments, and achieve sustainable development, the cogeneration system is the core essence of China's construction of low-carbon cities. The construction of a combined heat and power system means a socio-technical transition from traditional energy technology and heat and power supply systems. Referring to the construction process of Beddington's "zero-carbon community", most cities in China are still in the "low-carbon pilot stage", and have entered the "rapid development stage" after the country vigorously promotes the low-carbon pilot. The transformation of cogeneration system into the construction of low-carbon cities depends on the development path dominated by social and technical institutions. Based on the theory of socio-technological transformation, this paper adopts a multi-level analysis method to further construct the social environment, innovative organization and management institutions, and professional socio-technical institutions from the macro to the micro level from the role of the government, so as to promote the coordination and cooperation of all links and comprehensively promote the universalization of low-carbon cities.
Exploration and Practice of Teaching "Visual Expression Research" Course Oriented towards Outcomes-Based Education
Authors: Huang Hui , Meng Jiajia
Published: November 2024

To achieve the goal of cultivating high-quality innovative design talents among application-oriented graduate students in design fields, this paper explores and practices goal-oriented teaching methods in the "Visual Expression Research" course. Based on the theory of Outcomes-Based Education (OBE) and considering the course's emphasis on both theory and practice, curriculum reforms are implemented in terms of teaching content, teaching approaches, and evaluation criteria. Particularly, the application of blended learning in the design teaching process and the practice of multi-dimensional teaching evaluation are highlighted. Under the guidance of OBE theory, the "Visual Expression Research" course, combined with the blended learning mode, can enhance students' initiative and enthusiasm. It establishes the main role of teacher-student interaction and online-offline teaching, stimulates learning interest, and thus improves teaching quality.
The Value, Function and Realization Path of Ideological and Political Education in the Age of Artificial Intelligence
Authors: Li Shuang , Li Wanyin , Chen Junbo , Fan Yunting
Published: November 2024

Along with the extensive use of artificial intelligence in the whole society, the deep integration of AI and education has become an inevitable trend. The value implication of AI on ideological and political education is reflected in the integration of AI technology with the four basic elements of ideological and political education: the subject, object, mediator and ring, which endows the traditional mode of ideological and political education with new vitality and great potential for development, and forms a personalized education mode, refined education management, panoramic education evaluation and intelligent education environment. Thus, it provides research tools and research methods for research subjects to deepen their understanding of the objectivity and universality of the function of ideological and political education, and endows the academic environment of ideological and political education function with more mobility, which makes the content of the research of ideological and political education function richer. However, while AI boosts the epochal development of ideological and political education work, it also has problems such as weakening the discourse status of the subject of ideological and political education, deviation of educational value and lack of humanistic care, and ethical risks of data and privacy leakage. Therefore, in the era of AI, it is necessary to strengthen the role authority and ideological guidance of the main body of the discourse of ideological and political education, balance the “intelligence” and “emotional” of ideological and political education, and adhere to the bottom-line requirements of the ethical safeguard mechanism of ideological and political education, so as to make artificial intelligence play a more effective role in ideological and political education. AI can play a more effective role in ideological and political education.
Reforming Civil Engineering Practice Teaching: A Case Study on Material Testing in Civil Engineering
Authors: Li Lingxu , Ma Mingchang , Ma Zitong , Sun Yifeng
Published: November 2024

Currently, applied universities in China are advancing the reform of training models to foster well-rounded student development in areas of ethics, intellect, physical fitness, aesthetics, and practical skills. These institutions place a strong emphasis on social practice education, continuously enhancing training quality, integrating diverse cultural elements, and cultivating professionals with practical innovation and modern management skills. The civil engineering program specifically aims to develop high-caliber professionals with a solid grounding in contemporary civil engineering theories and techniques. As an essential practical course within the Civil Engineering Materials curriculum, the Civil Engineering Materials Testing course plays a critical role in fulfilling graduation requirements. Given evolving societal, economic, cultural, scientific, and technological needs, this course holds a foundational and central position in the civil engineering talent training system.
Innovative Thoughts on Employee Training in Enterprise Human Resource Management
Authors: Yao Shaokai
Published: November 2024

In the current social context, the competition among enterprises is increasingly fierce, and the competition between modern enterprises is essentially a competition for talent. If enterprises want to sustain development in such a context, they should give high priority to employee training work. However, affected by multiple factors, some internal managers and relevant staff within enterprises do not give high importance to employee training, lack systematic cognition of the related work, and the training content lacks targeting, resulting in poor final effects. What’s more, in corporate human resource management, the employee training work is just a formality, directly reducing the initiative of employee participation. To further improve the effectiveness and quality of employee training, in the process of conducting human resource management work, enterprises must highly value the significance of employee training, target the disadvantages existing in traditional employee training, formulate targeted solutions, enhance the practicality and targeting of employee training, further enhance the professional capabilities and comprehensive qualities of employees, provide ample talent guarantee for the sustained development of the enterprise, and meet the needs of future continuous development.
The Impact of Service Attitude of Medical Staff on Patient Satisfaction and the Mediating Effect of Patient Commitment
Authors: Tian Guanghua , Ariffin Indang Ariati Binti , Tham Jacquline
Published: November 2024

This study aims to investigate the impact of service attitude of medical staff on patient satisfaction, as well as the mediating role of patient commitment in this relationship. The research was conducted with a sample of 1092 outpatients in Anhui province, China. Data were collected through a questionnaire method between 14 Mar 2024 to 15 Apr 2024. The data analysis employed descriptive statistical methods, exploratory factor analysis, reliability analysis, and the path coefficient method to ascertain the hypotheses. The findings of this study indicate that service attitude significantly influences both patient satisfaction and patient commitment, and patient commitment significantly influences patient satisfaction. Additionally, another key outcome of this research is the identification of a mediating effect of patient commitment on the relationship between service attitude and patient commitment. The findings offer valuable theoretical insights and practical guidance for the development and management of primary medical institutions in China.
Effects of Rice Husk Ash Addition on the Refractory Properties of Owo Clay
Authors:   Department of Metallurgical and Materials Engineering, Enugu State University of Science and Technology, Agbani (Nigeria), West Africa., Onyia Tobias Makuochukwu , Idenyi Dr. Ndubuisi Edennaya ,   Department of Mechanical Engineering, Ebonyi State University, Abakaliki (Nigeria), West Africa.
Published: November 2024

This research investigates the effect of rice husk ash (RHA) addition on the refractory properties of Owo clay. The clay is blended with RHA in increments of 5 Percent for each experimental run. The blended material undergoes exposure to temperatures ranging from normal crucible liner conditions to 1200 Degree C, followed by characterization for shrinkage, porosity, density, water absorption, and modulus of rupture. Results indicate that total shrinkage increases with RHA content throughout the experimental phase but stability was observed at 10 Percent RHA. Porosity decreases with increasing RHA content, with the 10 Percent RHA blend showing the most consistent decrease. RHA enhances compressive strength, reaching a peak of 24 Newtons per square millimetre for 5 Percent RHA at 1200 Degree C, and a minimum of 10 Newtons per square millimetre for 5 Percent RHA at 900 Degree C. Bulk density increases with decreasing porosity as temperature rises. Overall, the 90 Percent 10 Percent Owo clay RHA Clay blend demonstrates the most suitable properties for industrial applications.
A Comprehensive Methodology for Data Compression and Decompression Utilizing Huffman Coding, LZW Compression, and RunLength Encoding, Integrated with Data Encryption Standard (DES) and Advanced Encryption Standard (AES) for Enhanced Security
Authors:   Department of Communication Engineering University of Science and Technology Beijing China., Khan Sangeen
Published: November 2024

With advancements in communication technologies, transitioning from 5G to 6G systems has led to exponential data growth, requiring secure and efficient data transmission solutions. This study integrates data compression techniques Huffman Coding, Lempel Ziv Welch (LZW), and Run-Length Encoding (RLE) with symmetric encryption algorithms, AES (Advanced Encryption Standard) and DES (Data Encryption Standard). The primary goal is to enhance computational performance while ensuring data security. Using a 32 byte dataset and implementing the algorithms in Go language via Visual Studio IDE, results demonstrate the significant reduction in encryption time when combining compression and encryption. Among the AES combinations, AES with Huffman Coding showed the highest efficiency, reducing encryption time by approximately 15 Percent compared to standalone AES. Similarly, DES paired with LZW compression achieved a 20 Percent improvement in computational time over standalone DES. The findings emphasize that selecting the optimal combination depends on data type and user requirements, facilitating secure and efficient communication in high bandwidth, low latency 6G systems. This research underscores the potential of cryptography, combined with compression, to enhance data transmission efficiency without compromising security. The integration approach highlights cryptographic strength in safeguarding big data, addressing challenges in modern technologies like the Internet of Everything (IoE). These results establish a foundation for future secure communication frameworks, promoting reliable and scalable cryptographic solutions tailored for 6G and beyond.
Securing BitCoin Price Prediction using the LSTM Machine Learning Model
Authors:   Professor, School of Computing, SASTRA University, Thanjavur., Balasubramanian Dr. Kannan
Published: November 2024

This research explores the application of Long Short Term Memory (LSTM) networks for short term Bitcoin price prediction, addressing the need for reliable models due to Bitcoins high volatility and trading volume. The study employs historical data from Kaggle to predict the direction and magnitude of price changes within a five minute interval. Implementation includes preprocessing the data, normalizing prices, and generating sequences for LSTM input. Two LSTM models were developed: one for directional prediction and another for magnitude. Training results showed a directional accuracy of approximately 75.10 Percent, demonstrating the feasibility of LSTM networks for financial forecasting and contributing to Bitcoin price prediction research, setting the stage for future real time applications.
An Analysis of the Implementation, Outcomes, and Challenges of NABARD's Self-Help Group Bank Linkage Programme in Assam, India
Authors:   M. Com 4th Semester, Royal School of Commerce, The Assam Royal Global University, Guwahati (Assam), India., Ahmed Abu Shafique , Chakraborty Dr. Sudip ,   Associate Professor, Royal School of Commerce, The Assam Royal Global University, Guwahati (Assam), India.
Published: November 2024

Self Help Groups (SHGs) have become a powerful tool for reducing poverty and empowering women worldwide. (Parida and Sinha, 2010 [1]) The connection of these groups to formal banking institutions, an initiative led by the National Bank for Agriculture and Rural Development (NABARD) in India, has significantly enhanced their socio economic impact. Assam, which is a state with a variety of socio economic challenges, is playing a crucial role in promoting financial inclusion and grassroots development. This study examines the status of NABARDs SHG Bank Linkage Programme in Assam, examining its implementation, outcomes, and challenges. Focusing on Assam, with its unique socio cultural dynamics and developmental disparities, this research seeks to provide insights that can inform tailored policy interventions and program improvements.
Compare the open-looped DBS and closed-looped DBS on treatment on tourette syndrome
Authors: Wang Manqi
Published: November 2024

Abstract. Tourette Syndrome (TS), a complex neurodevelopmental disorder featured by persistent motor and vocal tics, has seen Deep Brain Stimulation (DBS) emerge as an efficacious treatment option for refractory cases. This study aims to systematically review and compare the roles of open-loop and closed-loop DBS modalities in treating TS, to elucidate their respective strengths, priorities, and clinical outcomes. Through a comprehensive literature review and data analysis, this paper delves into the mechanisms, technical advantages, and effectiveness of both DBS paradigms in managing TS symptoms, mitigating comorbidities, and enhancing quality of life. Furthermore, the disparities in safety, tolerability, long-term efficacy, and the influence of patient-specific requirements on therapeutic strategy selection are evaluated. Besides, this paper also culminates with a summary and outlook, advocating for ongoing exploration to refine closed-loop DBS pathways and concurrent appraisal of open-loop DBS within specific patient cohorts, thereby advancing the precision and personalization of TS therapy.