bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimization and Characterization of Flavipin Produced by Aspergillus Terreus
Authors: Qasim Mohammed Jasim
Published: April 2023

The secondary metabolites of microorganisms serve as defence or signalling molecules in ecological interactions, revealing substantial survival benefits in nature. As a result, many researchers have concentrated on screening and optimizing the production of these molecules from natural sources such as microorganisms with the objective of pharmacological uses, primarily as antibiotics or anticancer agents. In this study, 80 isolates of Aspergillus were investigated for the production of flavipin. These fungi were collected from various locations and laboratories. Flavipin was estimated by using a standard curve, then purified by using silica gel chromatography, followed by identification using thin layer chromatography (TLC), and High Performance liquid chromatography (HPLC). The fermentation conditions were carried out at the Central Health Laboratory/Maysan Health Directorate from April 2021 to August 2022. Out of eighty isolates of Aspergillus, only one isolate was identified as producer of flavipin which was Aspergillus terreus. According to HPLC analysis, the retention times of flavipin and its standard were 7.7 minutes and 7.6 minutes, respectively. By using the TLC technique, the relative flow (Rf) value was 0.55 cm for both standard flavipin and flavipin. The optimization of growth conditions and production of flavipin were studied. It is revealed that optimum conditions were as follows: pH 7 on 16 days, the temperature of 25oC for 12 days, culture volume of 50 ml on the 16th day, shaking speed of 150 rpm on the 12th day, inoculum size of 8 fungal agar disc on the 12th day, the optimal incubation period of 14 days, and Potato Dextrose Broth as the optimal culture media.  The aim of the study was to determination of optimal conditions for the flavipin production that produced by Aspergillus terreus. For yielding a profuse amount of flavipin, the incubation and fermentation conditions such as temperature, the culture volume, shaking speed, inoculum size, pH of the medium, incubation period, and the type of culture media should be considered and the optimal one must be chosen.
Design of a New Bioluminescence Sensor Using an Arduino Device Linked to Bluetooth Mobile Phone and USB Computer to Measure Triglycerides
Authors: Ali Ammar Mohammed , Kadhem Mustafa Abdul
Published: April 2023

In this work, a new device is designed for measuring the light intensity of the Bioluminescence reaction between Luminol with Hydrogen peroxide that is produced as an activity of Triglycerides Phosphate Oxidase. The project includes the use of a homemade and semi-automated device for the determination of Chemiluminescence (CL) and Bioluminescence light by direct reaction analysis of Luminol with oxidant and using a Mobile –phone as a recorder which is employed in chemistry with Arduino and applied this device into the enzymatic reaction for determine Triglyceride by this new methods. The method is easy, simple, and rapid with high sensitivity for the determination of hydrogen peroxide. The light of the Bioluminescence reaction of Luminol (5-amino-2,3-dihydro-1,4_phthalazinedione) with oxidant (H2O2) was sensed by photocell and the signal was sent to Mobile. The method used to determine glycerol and compare the results of the device with real value to give high accuracy, Triglyceride was determined in its kit. It gave 99.2 and ±0.1 of Recovery and RSD, respectively.
Isolation, Identification and Antibacterial Activity of Alkaloid Compound N-Methylcytisine from Cyanobacterium Hapalosiphon Aureus
Authors: Al-Mousawi Nida J. M. , Al-Assadi Iqbal J. , Al-Aarajy Moussa J.
Published: April 2023

In this study, one species of algae, belongated to cyanophyta : Hapalosiphon aureus west and west 1897 were isolated, identified and purified. The extracts of algal isolates were testing to clarify their ability on growth inhibition on each of gram +ve and gram –ve bacteria E.coli & S. aureus, filamentous fungi  A. fumigatus, and yeasts C.albican. The extracted alkaloid of species H.aureus showed higher inhibition activity. In our literature survey, the alkaloid compound analog N- methylcytisine was isolated for the first time from the H.aureus . This compound was characterized using Thin Layer Chromatography (TLC), Ultra Violet Spectrum (UV), Infrared Spectrum (IR), Proton Nuclear Magnetic Resonance Spectroscopy (1HNMR), Melting Point and Solubility in organic and inorganic solvents. The biological activity of this alkaloid was determined using the Minimal Inhibitory Concentration (MIC) against six bacterial isolates. The results showed inhibition in 33.3% growth of bacteria on 150 μg/ml concentration level, while the MIC against six fungi isolates showed inhibition of growth 33.3% at 50 μg/ml compared to standard antibiotic. The median lethal dose (LD50) showed no toxicity, no cytotoxicity and no effect on human red blood cells for 18 hours.
Adoption Behaviour of Climate-resilient Agricultural Practices in Punjab under NICRA Project
Authors: Sodhi G. P. S. , Singh R. K. , Dhillon G. S. , Ahuja Sanjeev , Kaur Arvindpreet , K Sunidhi , Kaur Taranreet , Murai Ashish S. , Singh Rajbir , Kaur Simerjeet
Published: April 2023

An integrated package of climate-resilient technologies was demonstrated in one village per 4 selected districts namely Bathinda, Faridkot, Roopnagar and Fatehgarh Sahib of Punjab. The major objective was to augment the resilience of agricultural systems, both crop production and livestock farming to climate vulnerability. From 2011-2020, major interventions made in crop production system were; crop residue management, zero tillage, quality seed, green manuring, biofertilizers and promotion of water saving technologies such as laser land levelling, direct seeded rice, short to medium duration rice varieties, etc. Major interventions made in livestock production system included green fodder production round the year, silage making, mineral mixture, uromin lick availability and regular vaccinations. To improve livelihood, subsidiary occupations like dairy farm, backyard poultry, piggery, jaggery production and protected cultivation units were established in the NICRA villages. Farmers were highly convinced to adopt the recommended practices but adoption level of demonstrated natural resource management technologies was variable and specific to a district. The satisfying results were witnessed under the NICRA project and there was an increase in the adaptive capacities, and enhanced incomes. NICRA villages functioned as model villages and became knowledge hubs/centres for out-scaling technologies in large areas.
Enhancing Effectiveness of Farm School through Community Wall Magazine (CWM): A Field Experimental Study
Authors: Malik Netrapal , Dubey Shantanu Kumar
Published: April 2023

A field experimental study was conducted in Aligarh District of Uttar Pradesh to assess the feasibility of enhancing the effectiveness of Farm Schools (FS) through Community Wall Magazine (CWM). Four treatments with two replications were taken in the study. Treatments were information sharing through CWM (T1), information sharing through FS (T2) and supporting information sharing through FS with CWM (T3). Treatment T0 was taken to eliminate the effect of extraneous variables. Before and after treatment score of gain in the knowledge level of farmers regarding paddy cultivation practices was measured with the help of a knowledge test developed for the study. Matching in terms of the general profile of the farmers under all the replications was ensured before exposure to the treatments. Total farmers under the study were 200. Through CWM 21.83 per cent enhancement in knowledge level regarding rice cultivation practices of the farmers was observed. Due to the effect of FS on rice, 47.18 per cent enhancement in knowledge level was observed. The FS on rice which were supported with the information sharing through CWM 61.02 per cent enhancement in the knowledge level of beneficiary farmers was observed.
Good coverings of proximal Alexandrov spaces. Path cycles in the extension of the Mitsuishi-Yamaguchi good covering and Jordan Curve Theorems
Authors: Peters James Francis , Vergili Tane
Published: April 2023

This paper introduces proximal path cycles, which lead to the main results in this paper, namely, extensions of the Mitsuishi-Yamaguchi Good Coverning Theorem with different forms of Tanaka good cover of an Alexandrov space equipped with a proximity relation as well as extension of the Jordan curve theorem. In this work, a path cycle is a sequence of maps h1,...,hi,...,hn-1 mod n in which hi  : [ 0,1 ] → X and hi(1) = hi+1(0) provide the structure of a path-connected cycle that has no end path. An application of these results is also given for the persistence of proximal video frame shapes that appear in path cycles.
Concepções das Tecnologias Digitais de Informação e Comunicação presentes na BNCC da área de matemática e suas tecnologias
Authors: Figueiredo Ronaldo Lage , Pedrosa Stella Maria Peixoto de Azevedo
Published: April 2023

Esta pesquisa tem por objetivo analisar a concepção das Tecnologias Digitais de Informação e Comunicação, TDIC, presente na Base Nacional Comum Curricular, BNCC, da área de Matemática e suas Tecnologias do ensino médio. Para a realização dessa análise partimos da seguinte indagação: “como a BNCC interpreta o uso das Tecnologias Digitais, TD, no ensino de Matemática do ensino médio?”. Com intuito de atender o objetivo proposto, este estudo adota uma metodologia qualitativa, descritiva, do tipo documental, a partir do documento da BNCC implementado em 2018 para a etapa do ensino médio. Como resultado, evidenciou-se que, a forma que a BNCC aborda o uso das TD no ensino de Matemática para o ensino médio é instrumentalista, ou seja, a BNCC propõe o uso das TD para a resolução de problemas e/ou realizar modelagem matemática. Portanto, esse estudo sugestionou uma reflexão que as TDIC não são neutras, e que, as mesmas, não são agentes modificadoras ou solucionadores para a aprendizagem de Matemática.
Comunidade de prática de redes sociais como processo de formação para professores e licenciandos
Authors: Oliveira Jéssica Maria , Carvalho Ana Beatriz Gomes
Published: April 2023

O objetivo deste estudo foi analisar o uso de Redes Sociais como Comunidade de Prática no processo de formação de professores e licenciandos. Este trabalho é um recorte de uma pesquisa de mestrado e está fundamentado no contexto da Cultura Digital, Redes Sociais e Educação e no conceito das Comunidades de Prática. Foi adotada uma abordagem qualitativa caracterizada como pesquisa-formação (SANTOS, 2019), por meio de um curso on-line que obteve a inscrição de 67 professores e licenciandos de diversas partes do Brasil, durante 4 semanas. Os resultados indicados pelos questionários on-line e pela observação da participação dos professores e licenciandos no processo de formação demonstram que a utilização e a produção nas Redes Sociais podem contribuir de forma significativa e contextualizada para melhorar metodologias educacionais no ensino de conteúdos em várias etapas de ensino da Educação Básica. O estudo possibilitou ampliar as estratégias didáticas que os professores e licenciandos participantes já possuem, utilizando as interações na Comunidade de Prática, para melhorar a interação com seus alunos e utilizar as Redes Sociais em sala de aula de maneira mais efetiva e significativa.
Desenvolvimento de um jogo educativo utilizando Scratch e sua aplicação no ensino de matemática básica: um relato de experiência
Authors: Cavalcante Jonas Lima , Assís Marcelo Amaro de , Barros Erlânio Freire , Lessa Miguel Angelo Monteiro
Published: April 2023

No cenário atual, o uso de jogos digitais no ambiente escolar vem se tornando uma ferramenta cada vez mais necessária para o desenvolvimento de habilidades de assimilação e resolução de problemas. No presente trabalho, descrevemos a experiência de discentes do ensino básico com o jogo Math Adventure, desenvolvido na ferramenta Scratch e voltado à resolução de problemas matemáticos. O estudo foi realizado com 12 estudantes de 9° ano de escola pública e coordenado por dois graduandos do curso de Licenciatura em Computação (LC) da Universidade Estadual do Ceará (UECE - Mombaça), ambos matriculados na disciplina de Fundamentos e Análise de Software Educativo (FASE). O objetivo foi avaliar a interação destes estudantes com o Math Adventure no ambiente escolar e monitorar seu desenvolvimento pedagógico a partir das ferramentas disponibilizadas pelo jogo. Após terem seus perfis traçados através de questionários, os alunos foram divididos em duplas e orientados a solucionar, com auxílio do jogo, operações básicas matemáticas. Ao final, pudemos verificar que o jogo proporcionou um ambiente educativo desafiador, incentivando o aprendizado de matemática de forma lúdica, intuitiva e divertida para estudantes da rede municipal de ensino de Mombaça – CE
Simulation of Dynamic Processes in the Human Body using Differential Equations with Discontinuous Right-Hand Side
Authors: Горбунов Д. В. , Гавриленко Т. В.
Published: April 2023

в работе рассматривается задача математического моделирования функциональных систем организма человека в рамках исследований динамики изменения параметров подсистем с хаотической, самоорганизующейся структурой. Данная задача является актуальной ввиду необходимости изучения взаимодействия подсистем сложной системы организма человека, в том числе поиска причин возникновения патологических процессов. Разработанные методы математического моделирования на основе дифференциальных уравнений с разрывной правой частью позволяют учитывать процесс самоорганизации динамических подсистем. Задача удержания стационарного состояния базируется на приближении решений к уникальной линии разрыва системы, что позволяет эффективно воспроизводить динамику подсистемы организма человека. В свою очередь, линия разрыва генерируется в процессе моделирования и корректируется в зависимости от текущего состояния подсистемы и стационарного состояния, что существенно приближает к динамике реальной живой системы. Также в работе представлены результаты применения метода математического моделирования на примере работы биомеханической системы человека (частный случай). Апробация показала высокую адекватность метода математического моделирования и эффективность численного решения на основе сравнительного анализа результатов моделирования и данных натурных экспериментов. Результаты расчетов динамики движений биомеханической системы показали устойчивость на серии вычислительных экспериментов.

this study considers the simulation of the human body’s functional systems as part of the research into the parameter variation dynamics in subsystems with a chaotic, self-organizing structure. The problem is significant as we need to study the interaction between the subsystems of a complex system, the human body, and find the causes of pathologies. The proposed simulation method uses differential equations with a discontinuous right-hand side. It enables us to account for self-organization in dynamic subsystems. The stationary state is maintained as the solution approaches a unique discontinuity line in the system, as it correctly reproduces the dynamics of a subsystem in the human body. The discontinuity line is generated during the simulation and adjusted to match the current state of the subsystem and the stationary state, which is a much better representation of the dynamics of a real living system. The paper includes the simulation results of a human biomechanical system (a special case). The tests proved the simulation results are in good agreement with the experiments. The biomechanical system motion simulation results show stability in a series of computational experiments.
Approaches to the Simulation of Personal Income Variations During Epidemics
Authors: Петракова В. С. , Криворотько О. И.
Published: April 2023

в статье предлагаются две модели, описывающие влияние динамики распространения вируса на такие макроэкономические показатели, как численность рабочей силы и уровень среднедушевого дохода населения. Первая предложенная модель объединяет камерный подход SIR к моделированию распространения эпидемий и урбанистическую модель Лотки-Вольтерры. Вторая обобщает предложенную дифференциальную модель на задачу оптимального управления. Приведено сравнение результатов моделирования между собой и реальными данными на примере Новосибирской области за 2020–2021 гг. Для модели оптимального управления предложено несколько сценариев, которые могут быть использованы при расширении модели для моделирования отличной от рассматриваемой экономико-эпидемиологической ситуации.

this study proposes two models representing the impact of the virus spread on such macroeconomic metrics as the labor force size and per capita income. The first model combines the SIR compartmental epidemics modeling and the Lotka-Volterra model. The second one extends the proposed differential model to the optimal control problem. The simulation results are compared with each other and real-world data for the Novosibirsk Region, 2020–2021. We used several scenarios for the optimal control model to further expand the model to other economic and epidemiological conditions.
Implicit Communities Defined on the Graph for Interacting Objects
Authors: Чеповский А. А.
Published: April 2023

в работе рассматриваются текущие и перспективные задачи анализа графов, представляющих сложные сети взаимодействующих объектов. Описаны предметные области, для которых актуальны данные модели, рассматриваются практика, проблемы анализа графов социальных сетей и выделения на них неявных сообществ. Обсуждаются основные алгоритмы выделения сообществ на графах и проблема тестирования качества получаемых разбиений. Автором предложены перспективные, на его взгляд, направления развития данной тематики для графов, полученных при импорте данных из реальных социальных сетей. Показана актуальность подходов, предложенных в предыдущих работах автора.

the paper considers the problems of analyzing graphs that represent complex networks of interacting objects. The relevant domains are described, social network graph analysis and implicit community detection are considered. The key graph-based community detection algorithms and the quality assessment of their results are discussed. The author proposed promising development trends using the graphs representing actual social networks. The relevance of the approaches proposed in the author’s previous works is also highlighted.
Spectral Processing of Acoustic Signals for Pipeline Security Systems
Authors: Романовский М. В. , Солдатов А. И.
Published: April 2023

в статье приведен обзор существующих систем физической защиты магистральных трубопроводов от несанкционированного действия. Показано, что наиболее перспективной будет схема охраны с акустическим датчиком и оптико-электронной системой распознавания, действующая по алгоритму: срабатывание акустического датчика — подтверждение по акустическому алгоритму — подтверждение оптико-электронной системой наблюдения — тревога. В основе распознавания акустических сигналов использован метод прямого преобразования Фурье для определения частотного спектра акустических сигналов и сравнения их с эталонными. Вышеупомянутый метод прямого преобразования основан на разложении суммарных акустических сигналов, улавливаемых датчиком, на исходные синусоиды. Данная работа направлена на модернизацию системы физической защиты по отношению к магистральным трубопроводам по доставке нефтепродукта и как следствие — к повышению уровня защищенности таких объектов. Предлагаемый метод модернизации системы физической защиты позволит обеспечить условия для однозначного определения несанкционированных действий путем анализа и сопоставления звукового сигнала с базой сигналов предварительно записанных звуков и решить ряд проблем актуальной темы обеспечения безопасности и сохранности линейных магистральных нефтеи газо-трубопроводов. Также такое решение позволит минимизировать частоту ложных срабатываний технических средств физической защиты.

this paper is an overview of the existing pipeline security systems preventing unauthorized access to the pipe. It is shown that the most suitable solution is an acoustic sensor and optoelectronic recognition system. It operates as follows: the acoustic sensor is activated – the acoustic algorithm confirms the alarm – the optoelectronic system confirms the alarm – the alarm is triggered. The direct Fourier transform is used for acoustic signal recognition to identify the frequency spectrum of acoustic signals and compare it with the reference one. The above-mentioned direct transform includes a decomposition of the total acoustic signal from the sensor into original sinusoids. The purpose of this study is to upgrade the oil pipeline security systems for better efficiency. The proposed upgrade method unambiguously identifies any unauthorized access by analyzing and comparing the audio signal with the reference signal from a database of pre-recorded sounds to protect oil and gas pipelines. The solution also minimizes the false alarm rate.
O ESTUDO SOBRE A APLICAÇÃO DO INSTITUTO DA TENTATIVA, CRIME CONSUMADO OU CRIME IMPOSSÍVEL NO FURTO SOB VIGILÂNCIA
Authors: Chaves Adryelle Carolina de Azevedo
Published: April 2023

Tendo em vista a discussão acerca de qual instituto se aplicaria ao furto praticado com a presença de aparatos de vigilância, pesquisa-se sobre qual seria o mais correto a ser aplicado (tentativa, crime consumado ou crime impossível), a fim de alcançar a clareza sobre o estudo e a melhor aplicação ao caso concreto. Para tanto, é necessário um aprofundamento sobre a tentativa (conatus), crime consumado e o crime impossível além de todas as teorias que embasam a aplicabilidade de tais institutos, o entendimento dos principais tribunais do Brasil e o conhecimento apresentado por determinados doutrinadores sobre o assunto. Realiza-se, então, uma pesquisa pautada na norma, nos julgados e nos entendimentos doutrinários. Diante disso, verifica-se que já houve grande divergência sobre o assunto, porém os tribunais têm consolidado uma determinada concepção a respeito do tema, entretanto, ainda há inconsonâncias entre doutrinadores, o que impõe a constatação de que há que se levar primordialmente o caso concreto para a definição de qual unidade irá ser aplicável de forma mais prudente e justa possível.
Evaluation of precision, accuracy and threshold for the design of vibrotactile feedback in eye tracking applications
Authors: Fischer Anke , Wendt Thomas M. , Stiglmeier Lukas , Gawron Philipp , Van Laerhoven Kristof
Published: April 2023

Abstract. Novel approaches for the design of assistive technology controls propose the usage of eye tracking devices such as for smart wheelchairs and robotic arms. The advantages of artificial feedback, especially vibrotactile feedback, as opposed to their use in prostheses, have not been sufficiently explored. Vibrotactile feedback reduces the cognitive load on the visual and auditory channel. It provides tactile sensation, resulting in better use of assistive technologies. In this study the impact of vibration on the precision and accuracy of a head-worn eye tracking device is investigated. The presented system is suitable for further research in the field of artificial feedback. Vibration was perceivable for all participants, yet it does not produce any significant deviations in precision and accuracy.
“Billions in Debt and Still Surviving”: Curing the Female Shopper in Confessions of a Shopaholic
Authors: Sapui Meghna
Published: April 2023

This paper analyses P.J. Hogan’s Confessions of a Shopaholic (2009) in three sections. In the first section, it studies how the film maps shopping as an illness that needs to be cured onto the body of its female heroine. It does so, as is argued here, by portraying her as a patient suffering from Compulsive Buying Disorder (CBD). In the second part, it traces how Confessions necessitates the cure of the female shopper, given its background of the Great Recession and how this holds generic significance for the romantic comedy. The paper then concludes by charting the heroine’s cure in group therapy as predicated upon the principle of the Foucauldian confession and how this then resolves the narrative as, what Diane Negra calls, one of “adjusted ambitions.”
ANALISIS PEMBERIAN REWARD DAN PUNISHMENT PESERTA DIDIK DALAM PENINGKATAN MUTU PENDIDIKAN
Authors: Sahade Sahade , Rijal Syamsu
Published: April 2023

Penelitian ini bertujuan untuk mengetahui: 1) pengaruh pemberian reward dan punishment secara parsial dan secara simultan terhadap peningkatan mutu pendidikan dan 2) variabel yang pengaruhnya dominan terhadap peningkatan mutu pendidikan. Variabel dalam penelitian ini adalah reward sebagai variabel bebas pertama (X1), punishment sebagai variabel bebas kedua (X2) dan mutu pendidikan sebagai variabel terikat (Y). Populasi dalam penelitian ini yaitu seluruh peserta didik di SMK Negeri 1 Makassar yang berjumlah 1400 peserta didik  yang terdiri atas 415 peserta didik  laki-laki dan 985 peserta didik  perempuan dengan jumlah rombel sebanyak 40. Teknik pengambilan sampel menggunakan teknik purposive sampling, sampel berdasar kepentingan dan keterbatasan sehingga mengambil 5% dari keseluruhan populasi yaitu 70 peserta didik. Teknik pengumpulan data yang digunakan dengan menggunakan kuesioner dan data dokumen sekolah yang relevan. Teknik analisis data menggunakan analisis deskriptif kuliatatif dengan persentase, uji instrumen, uji asumsi klasik dan uji hipotesis. Uji instrumen terdiri dari uji validitas dan uji reliabilitas. Uji asumsi klasik terdiri dari uji normalitas, uji multikolinieritas, uji autokorelasi dan uji heteroskadastisitas.Uji hipotesis terdiri dari regresi linear berganda, uji simultan (uji F), koefisien determinasi ganda (R2), uji parsial (uji t) dan koefisien determinasi parsial (r2). Hasil penelitian ini menunjukkan bahwa pemberian reward secara parsial berpengaruh signifikan terhadap terhadapa peningkatan mutu pendidikan dengan tingkat signifikan <0,05 dan punishment secara parsial berpengaruh signifikan terhadap mutu pendidikan dengan tingkat signifikan <0,05. Pemberian reward dan punishment secara simultan berpengaruh signifikan terhadap mutu pendidikan dengan tingkat signifikan <0,05, dan koefisien determinasi (R^2) yaitu sebesar 0,547 (54,7%) yang berarti bahwa pengaruh reward dan punishment terhadap mutu pendidikan adalah sebesar 54,7% sedangkan sisanya 45,3 dipengaruhi oleh faktor yang belum diteliti.
PENGARUH MODEL BLENDED PROBLEM BASED LEARNING BERBASIS LMS MOODLE TERHADAP MOTIVASI BELAJAR DAN HASIL BELAJAR MAHASISWA JURUSAN AKUNTANSI
Authors: Fakhri M. Miftach , Wahid Anwar , Fadhilatunisa Della , Surianto Dewi Fatmarani , Fajar B Muhammad , Hidayat Akmal
Published: April 2023

Penelitian ini bertujuan untuk: mengetahui model blended problem-based learning berbasis LMS Moodle yang berpengaruh dalam meningkatkan hasil dan motivasi belajar mahasiswa dan perbedaan hasil dan motivasi belajar mahasiswa yang diberikan pembelajaran model blended problem-based learning berbasis LMS Moodle dengan mahasiswa yang mengikuti model blended learning.  Desain penelitian yang dilaksanakan yaitu eksperimental semu (quasi experimental). Sampel penelitian terdiri dari kelas A yakni 34 orang dalam kelas eksperimen dan kelas D yakni 33 orang dalam kelas kontrol. Teknik pengambilan sampel yaitu purposive sampling. Hasil penelitian menjelaskan yaitu hasil análisis inferential dengan uji paired simple t test menjelaskan nilai t-hitung lebih besar dibandingkan t-tabel dengan nilai sig lebih kecil daripada 0.05 yang bermakna yaitu pelaksanaan model blended problem-based learning dapat membantu peningkatan hasil dan motivasi belajar mahasiswa. Selain itu, hasil dari uji independent simple t test menjelaskan yaitu nilai t-hitung lebih besar dibandingkan t-tabel dengan nilai sig lebih kecil daripada 0.05 yang bermakna yaitu hasil dan motivasi belajar mahasiswa kelas eksperimen mempunyai perbedaan secara signifikan dengan mahasiswa kelas kontrol.
TransLearning ASD: Detection of Autism Spectrum Disorder Using Domain Adaptation and Transfer Learning-Based Approach on RS-FMRI Data
Authors: Singh Samreen , Malhotra Deepti , Mengi Mehak
Published: April 2023

Autism Spectrum Disorder abbreviated as ASD, is a complex neuro-developmental disease specifically linked to nervous system that influences patients’ communicationand social behavior. Traditional clinical techniques used for the discovery of ASD fall short of definite and early ASD diagnosis. Consequently, biomarkers have been introduced in the field of ASD diagnosis and particularly, resting-state functional Magnetic Resonance Imaging (rs-fMRI) has posed as a valuable biomarker. Researchers have focused on utilizing the vast span of Artificial Intelligence techniques in combination with rs-fMRI, to build an effective framework for ASD detection. However, these systems have not been able to generalize to a larger set of patients, because of theheterogeneity in the available f-MRI dataset for ASD. Motivated from the aforementioned discussion, this study performs a comprehensive literature review of the existing systems covering a period of 2019-2021, thereby identifying several research gaps. To overcome the effect of existing implications, this paper expounds a TransLearning ASD framework which will achieve normalization of the heterogeneous fMRI data using domain adaptation followed by transfer learning technique for effective ASD prediction and to overcome the model generalization problem.
Development of Efficient Machine Learning Model to Detect Muliebrous
Authors: Nagar Rishabh , Jain Rinisha , Shukla Amogh
Published: April 2023

The Diabetes predicting machine learning models developed so far Diabetes risk calculators have a strong negative predictive value, which means they can help identify people who are unlikely to develop diabetes. Tests that reflect beta cell function may assist determine the type of diabetes or the requirement for insulin indefinitely. Machine Learning models can help predict whether or not a female is suffering from diabetes while assessing different health conditions such as; increased glucose level, age, family hereditary and blood pressure. Our project focuses on making machine learning models which can predict if a person suffers from diabetes while using specific health conditions as constraints. So different machine learning models will be used in order to get concluding results and whichever model serves to be most accurate will be used to improve the prediction system of diabetes amongst female patients. The project uses several concepts of machine learning, and the data used are databases obtained from national authorities to test and verify the results. Diabetes, if ignored, can cause various life threatening situations for the people suffering from it and hence we aim to help predict diabetes with accuracy among the female population.
Xử lý phế phẩm khóm tắc cậu với rơm bằng phương pháp lên men và tái sử dụng làm thức ăn cho gia súc nhai lại
Authors: Nguyễn Ngọc Trang
Published: April 2023

Nghiên cứu xử lý phế phẩm khóm Tắc Cậu lên men với rơm làm thức ăn cho gia súc nhai lại và phân tích các yếu tố ảnh hưởng đến nhu cầu thức ăn lên men cho gia súc nhai lại. Thí nghiệm bố trí 4 nghiệm thức và 4 lần lặp lại, các nghiệm thức gồm 30%, 45%, 60% và 75% với mỗi túi 2 kg sản phẩm; đánh giá cảm quan, pH và NH3 vào 0, 7, 14, 21 và 28 ngày. Thực hiện phỏng vấn hộ dân để phân tích yếu tố ảnh hưởng nhu cầu thức ăn lên men.

Kết quả cho thấy sau 28 ngày, nghiệm thức 75% vỏ khóm ủ chua đạt mức chất lượng tốt với giá trị pH là 4,03 và NH3 là 166 (mg/kg vật chất khô). Mô hình hồi quy tuyến tính đa biến được xây dựng nhằm xác định yếu tố ảnh hưởng đến nhu cầu sử dụng thức ăn lên men (P<0,05; R2 điều chỉnh là 0,767). Sự quan tâm đến nguồn gốc thức ăn của các hộ dân là yếu tố quan trọng ảnh hưởng đến nhu cầu thức ăn lên men (Beta = 0,468). Sản phẩm lên men từ phế phẩm khóm và rơm ở nghiệm thức 75% (NT75%) có thể tận dụng làm nguồn thức ăn cho gia súc nhai lại.
Nghiên cứu ứng dụng phương pháp sấy bọt chế biến sản phẩm bột từ trái dưa lưới (Cucumis melo L.)
Authors: Trần Xuân Hiển , Lê Thị Thúy Hằng , Lê Thị Thúy Loan , Nguyễn Tấn Hùng
Published: April 2023

Trái dưa lưới (Cucumis melo L.) chứa nhiều thành phần dinh dưỡng quý, có lợi cho sức khỏe con người. Mục đích nghiên cứu là đánh giá ảnh hưởng một số yếu tố công nghệ của quá trình sấy bọt đến thành phần dinh dưỡng của bột trái dưa lưới, bao gồm tỷ lệ gum arabic, maltodextrin và thời gian sấy microwave. Hiệu quả của quá trình sấy bọt được đánh giá thông qua hiệu suất thu hồi, hoạt động độ nước, giá trị màu sắc, độ hòa tan, hàm lượng acid tổng, vitamin C, carotenoid. Kết quả thực nghiệm cho thấy ở tỷ lệ gum arabic 10%; maltodextrin 3% với thời gian xử lý trong microwave 13 phút đạt hiệu suất thu hồi 44,39±0,12%; hoạt động nước 0,346±0,03; giá trị màu L và b là 38,86±0,04 - 5,73±0,035; độ hòa tan là 90,57±0,23%; hàm lượng acid tổng 0,52±0,01%; hàm lượng vitamin C 25,72±0,33 mg% và hàm lượng carotenoid 27,98±0,25 µg/g. Kết quả nghiên cứu này góp phần cung cấp dẫn liệu khoa học quý giá về trái dưa lưới, đặc biệt cho ngành công nghệ thực phẩm.
12 Labours Seminar Series: A multiscale modelling framework for computational physiology
Authors: Hunter Peter
Published: April 2023

There is much interest from the bioengineering healthcare community worldwide in the concept of a whole-body "digital twin" computational model that can be personalised and linked with data from clinical imaging and hospital-based functional measurements, as well as from a variety of wearable, implantable or home-based devices. To be effective this is going to require a new much more comprehensive and integrative approach to computational physiology. Models of subcellular biology that can take advantage of tissue biomarkers (blood, urine, etc) must be linked with measurements of genotype and included in models of higher-level physiological function at the tissue and organ scale. Surrogate (via machine learning) organ models must be included in organ systems and integrated into whole-body models that include autonomic neural and endocrine control. This talk will discuss the mathematical framework for an algorithmic energy-based approach to multiscale computational physiology that lends itself to crowd-sourcing the international effort needed to tackle the demanding requirements of a "digital" or "virtual" twin for healthcare.
Análisis de las cocineras tradicionales en las plazas de mercado de afluencia turística en Bogotá
Authors: Beltrán Rueda Karen , Mora Forero Jorge
Published: April 2023

Las cocineras tradicionales son personas que conservan representaciones características del territorio; el oficio culinario es una muestra de la tradición de una cultura. Esta investigación indaga el rol de estas personas y cómo se convierte en un insumo para el desarrollo del turismo en las plazas de mercado con afluencia de turistas en Bogotá. Por tanto, su objetivo consiste en analizar el papel de la cocinera como mujer portadora del conocimiento culinario, así como su aporte al patrimonio inmaterial y al desarrollo turístico local. Por consiguiente, se realizaron entrevistas semiestructuradas para identificar los conocimientos que tienen sobre la cocina colombiana y la forma en la que se adquieren estos conocimientos. Como resultado, las cocineras son portadoras del patrimonio inmaterial y representantes de la identidad cultural; la mayor parte de sus conocimientos culinarios se han obtenido por medio de tradición familiar o a la experiencia laboral. En conclusión, ellas mantienen vivas las tradiciones culturales a otras generaciones lo cual tiene un gran potencial para el turismo gastronómico.
KEHIDUPAN MEMULIAKAN TUHAN MENURUT 1 PETRUS 4:7-11
Authors: Supriadi Ester Riyanti
Published: April 2023

Tulisan ini secara khusus hendak memberikan sebuah pemahaman dan penerapan tentang bagaimana orang percaya seharusnya memiliki kehidupan yang memuliakan Tuhan menurut 1 Petrus 4:7-11. Penulis melakukan penulisan dengan pendekatan kualitatif yaitu metode observasi dengan pendekatan deskriptif analitis berdasarkan hermeneutik yakni interpretasi teks dengan analisis tekstual untuk mendapatkan makna dari teks. Sehingga dapat diketahui bahwa Kehidupan memuliakan Tuhan adalah cara perseorangan maupun kelompok orang percaya yang menunjukkan kemuliaan Tuhan melalui doa yang benar, mengasihi dengan tulus, dan melayani sesuai karunia yang dianugerahkan agar kemuliaan Tuhan dinyatakan menjelang kedatangan Tuhan dengan semakin bersatu sekalipun dalam penderitaan. Memuliakan Tuhan itu sendiri berarti sikap hati dan tindakan yang benar di hadapan Tuhan setiap saat untuk selalu menampilkan Kristus. Namun, masih banyak kehidupan orang percaya yang belum secara optimal memuliakan Tuhan baik setelah pandemic covid-19 saat ini maupun di masa sebelumnya yang hidup sesuai dengan pola-pola ilahi yang dibenarkan dalam Kitab Suci, salah satunya yang terdapat dalam 1 Petrus 4:7-11.
Can Silodosin Be Considered a Superior Substitute for Tamsulosin in Medical Expulsion Therapy for Patients with Lower Ureteral Calculi
Authors: Ahmed Aqeel , Rizvi Nabiha , Riaz Muhammad Mohsin , Ali Syed Asad , Asif Muhammad , . Haleemullah
Published: April 2023

Introduction: Urinary stones, also known as calculi, are a common urological problem affecting millions of people worldwide. Medical expulsion therapy (MET) is a commonly used treatment for lower ureteral calculi. Objectives: The main objective of the study is to find the role of silodosin as a superior substitute for tamsulosin in medical expulsion therapy for patients with lower ureteral calculi. Material and methods: The study design for this research article would be a randomized controlled trial comparing the efficacy and safety of silodosin and tamsulosin in medical expulsion therapy (MET) for patients with lower ureteral calculi. Patients with lower ureteral calculi who meet the inclusion criteria will be recruited for the study. Inclusion criteria may include age over 18 years, presence of lower ureteral calculus confirmed by imaging, and willingness to participate in the study. Exclusion criteria may include previous history of ureteral surgery, contraindication to alpha-blockers, and pregnancy. Results: A total of 100 participants were randomized to receive either silodosin (n=50) or tamsulosin (n=50) for medical expulsion therapy of lower ureteral calculi. The mean age of the participants was 45 years, and 60% were male. The stone expulsion rate at 4 weeks was 80% in the silodosin group and 75% in the tamsulosin group. There was no statistically significant difference between the two groups (p=0.54). Conclusion: In conclusion, the results of this study indicate that silodosin may not be a superior substitute for tamsulosin in medical expulsion therapy for patients with lower ureteral calculi. Both drugs demonstrated similar rates of stone expulsion and time to stone passage, as well as comparable safety profiles and patient satisfaction rates. Keywords: Silodosin, Tamsulosin, Lower Ureteral Calculi
The Frequency of H. Pylori Infection Among Patients Experiencing Digestive Endoscopy a Multi Center Study
Authors: Jan Naeem , Khan Atta Muhammad , Iltaf Muhammad
Published: April 2023

Background: The development of endoscopy, particularly gastroscopy, has changed the diagnosis of oeso-gastroduodenal disorders. there is little information accessible on the methods of intestinal endoscopy. Objective: The study's goal was to evaluate the pathologic diagnosis of endoscopic lesions and the presence of H. pylori during endoscopy (digestive examination). Methodology: 100 patients participated in the study, and there were 42 men and 58 women in it. This Multi center study was done department of gastroenterology and medical department hmc and lrh Peshawar between May 2022 and November 2022. The patients freely signed the permission form after being made informed of the goal. The data from each patient's gastrointestinal endoscopy were gathered for analysis. The research was authorized by the ethics and review committees of our institute's teaching hospital. The patients who had gastrointestinal endoscopies were included in this study by the inclusion criteria. Results: According to data, more female patients than male patients sought medical treatment for this problem. It was also observed that patients under the age of 45 comprised a greater percentage of the patient group than patients over the age of 45. Epigastralgia, which was reported by 72% of patients, was the most frequent sign and symptom, according to the data. Vomiting was the next most prevalent symptom, followed by gastrointestinal bleeding and weight loss. Several patients simultaneously reported many of these symptoms. Esophageal varices were shown to be associated with males, with a significant p-value of 0.045, it was discovered. The H. pylori-related gastritis was connected to a lesion. Conclusion: The study's objective was to determine the prevalence of H. pylori infection and the characteristics of endoscopic lesions in patients having gastrointestinal endoscopies. Analysis was done to determine the impact of different endoscopic lesions on various demographic parameters in this retrospective study. Age and stomach tumors were shown to be connected, and smoking may have had some influence on the development of peptic ulcers. And the majority of patients had an upper gastrointestinal endoscopy regularly. Keywords: H. Pylori infection, digestive endoscopy,
Clinical Features and Surgical Outcomes of Spinal Tumors: A Multicenter Study
Authors: Shah Syed Nasir , Haq Naeem Ul , Khan Muhammad Idris , Khan Zahid , Shah Walayat , Haq Main Ifthakar Ul
Published: April 2023

Objective: to evaluate the appearance, improvement, and complication rates of surgically removed spinal tumors. Material and Methods: After obtaining the ethics committee's approval, this multicenter study continued from Jan 2020 to Jan 2021 at the Department of Neurosurgery mmc Mardan. This research covered all instances of spinal tumors that were surgically removed during this time. Recurrent spinal tumors and metastatic spinal cancers admitted for conservative or palliative care were excluded from this investigation. A neurological state comparison at six months with preoperative status is recorded. Version 26 of Spss software is used to evaluate data. Results: 27 female and 20 male patients totaling 47, were operated on during this time. In our research, intradural extra medullary lesions, which affected 18 patients (38.29%) the most, were followed by epidural lesions, which involved 13 patients (27.65%). Nine patients (19.14%) had an intradural intramedullary lesion. Pain in the form of backache, radiculopathy, and radiculomyelopathy (30 patients, 63.8%) is the most typical manifestation of these malignancies. The second joint Presentation is a motor impairment shown as a weakness (27 cases, 58.51%). CSF leak occurs in 05 individuals, with the most common postoperative consequence (7.44%). 75.5% of patients get good from a decent symptom result (36). There is evidence of neurological dysfunction in 3 cases (5.31%). Conclusion: The preferred course of therapy for spinal tumors is microsurgical excision with acceptable morbidity and successful surgical findings. Keywords: Spinal tumors, Microsurgical treatment,
Prevalence and Clinical Features of Thalassemia Minor Cases
Authors: Faizan Muhammad , Rashid Nadia , Hussain Sumbal , Khan Ansa , Khan Jamshid , Zeb Salma , Ahmed Sardar Qaser
Published: April 2023

Background: Thalassemia, the most common heterogeneous single gene disorder causing sever genetic health problem in the world. In 1932 George and William gave it the name thalassemia derived from Greek words (“thallassa: mean sea) and (“aima: mean blood). The research was conducted on thalassemia minor patients in North Waziristan and some selected areas of Peshawar Khyber pakhtunkhwa. Methods: During this survey 100 thalassemia minor patients were interviewed belonging to different castes. It was observed that majority of the patients were from the age group 1-10 years both in male asn females. Different ethnic groups were interviewed such as Yousafzai, Halimzai, Dawar, Wazir, Noor khel, Musazai, Saidan, Miserkhal, Afridi, Miagan, and Afghan. Results: The most of the thalassemia minor patients belonged to rural area (62.4 %) while 36.6% patients were reported from urban area. The maximum number of thalassemia minor patients belonged to lower class which was reported 47% followed by middle class (35%) and rich people (18%). The parents of 64 patients were cousin while the parents of 36 patients had marriage out of the family. The birth abnormalities were also recorded and observed as abortion (30%), delay birth (23%), still birth (13%) and premature birth (17%). During this study it was observed that majority of the patients were of the moderate body status (54.5%) Interestingly the ratio of obese people was very low. While the ratio of thin people was 39.4%. The physical abnormalities found in thalassemia minor patients included eye, skin, ear, mental and bone and joint abnormalities. the people having the age from 1-10 have an average HB level of 9.45 g/dl while those having age of 41-60 have an average HB level of 11.58 g/dl. The physical infections also reported such as eye infection (39%), GIT infection (20%), Lung infection, Skin infection (16%), UTI (7%) and Ear infection (2%). Conclusion: This study provides an insight in to the mechanism of transmission of thalassemia in the family and suggest social awareness about the disadvantages of the interfamilial marriages. Keywords: Thalassemia, Consanguineous marriages, Hemoglobin, Birth Abnormalities, Infections.
Frequency of Polycystic Ovary Disease in Adolescent
Authors: Gul Nazish , Bibi Najma , Ghafoor Maria , Babar Rubina , Anbreen Fauzia
Published: April 2023

Introduction: Polycystic ovary syndrome (PCOS) is the most common cause of chronic hyper androgenic anovulation and the single most common cause of infertility in young women. Anovulatory cycles are frequent in adolescents. The common signs of adult hyperandrogenism are less reliable in adolescents than in adults: hirsutism is in a developmental phase, and acne vulgaris is common. Objective: To determine the frequency of polycystic ovary disease in adolescent presented to outdoor. Study Design and Setting: This cross sectional study was carried out in the Department of Obstetrics & Gynecology, DHQ, Zanana Hospital, Dera Ismail Khan. Duration of Study: This study was conducted from 1st July 2019 to 31st December 2019. Subjects and methods: A total of 128 girls presenting to OPD due to irregular periods were included. Ultrasound was done to all participants under supervision of consultant gynecologist of 3 years post fellow ship experience. 5 ml venous blood samples was collected from all participants by a 3rd year resident and was subsequently sent to laboratory for androgen levels. Polycystic ovary disease as per operational definition was noted. Results: Age range in this study was from 14 to 20 years with mean age of 18.195±1.29 years, mean weight 52.898±4.92 Kg, mean height 1.571±0.08 meters and mean BMI was 21.557±2.80 Kg/m2. 19.5% patients were with family history of polycystic ovary disease. Polycystic ovary disease was seen in 7.8% patients. Practical implication: To determine the frequency of polycystric ovary disease in adolescent presented to outdoor. Conclusion: Polycystic ovarian syndrome is affecting the lives of young unmarried girls. The clinical manifestations are variable with obesity playing the key role. Keywords: Adolescent, Irregular period, Polycystic ovary syndrome, Frequency
Rezension von: Miller, Matthias, Mit Brief und Revers
Authors: Setzler Wilfried , Miller Matthias
Published: April 2023

Matthias Miller: Mit Brief und Revers. Das Lehenswesen Württembergs im Spätmittelalter. Quellen - Funktion - Topographie. (Schriften zur südwestdeutschen Landeskunde, Band 52). DRW-Verlag Weinbrenner Leinfelden-Echterdingen 2004. 214 Seiten mit 8 Abbildungen und einer CD-ROM. Gebunden € 25,-. (Subskriptionspreis bis 31.12.2004, danach € 32,-). ISBN 3-87181-752-X