bluuebunny/crossref_metadata_2025 huggingface dataset:
Placental expression of estrogen and progesterone receptors and vascular endothelial growth factor in buffaloes suffering from uterine torsion
Authors: Amin Yahia A. , Elnegiry Ahmed Abdou , Awadalla Eatemad A. , Hussein Hassan A. , Mohamed Ragab H.
Published: February 2025

Background

Although several risk factors have been suggested for uterine torsion, the pathogenesis is still unclear. Therefore, the current study aims to investigate the pathogenesis of uterine torsion by assessing the histological, histochemical, and immunohistochemical changes that occur in the placenta obtained from uterine torsion cases. Immunohistochemical changes include investigation of the expression of estrogen receptors (ERs), progesterone receptors (PRs), and the vascular endothelial growth factor (VEGF) in the placental tissue.

Methods

Forty intrapartum dairy cows were included in this investigation. The cows were divided into two equal groups. The first group was the uterine torsion (UT) group, while the second group was the normal control group (Ctrl). After caesarian section treatment, placentas were collected from all animals in the study. Histopathological, histochemical, and immunohistochemical examinations were performed. Estrogen receptors, progesterone receptors, and vascular endothelial growth factor expression in the placenta were evaluated.

Results

The results revealed numerous trophoblast giant or binucleate cells in the trophoblastic epithelium. Through Masson’s trichrome technique, the distribution of collagen fibers as shiny, blue-colored stripes on the fetal mesenchyme was observed. Additionally, the results showed a strong, intense PAS-positive reaction in the cytoplasmic vesicles of most trophoblastic cells due to mucopolysaccharides. The immunohistochemical findings of the UT placenta revealed moderate to weak staining for ERs in contrast to those of the Ctrl placenta, which revealed moderate staining for ERs. In addition, non-statistical differences in the expression of PRs were found between the two tested groups. For VEGF, strong positive immunoreactivity was found in the Ctrl group compared to the UT group, which exhibits a general absence in many trophoblast cells.

Conclusion

It can be concluded that significant variation was observed in the placentas obtained from buffaloes suffering from UT compared to those obtained from normal pregnant ones. These significant variations were involved in the decreased expression of ERs and VEGF in the UT group compared to the normal Ctrl one. Investigating the expression of these placental molecules may monitor the changes in the placental tissue and provide insight into the pathogenesis of UT.
Development of computer adaptive tests to assess the psychological status of individuals with an eating disorder or type 2 diabetes
Authors: Horie Takeshi , Kurisu Ken , Inada Shuji , Kawahara Kenshi , Matsuyama Yutaka , Kikuchi Hiroe , Yamamoto Yoshiharu , Yamauchi Toshimasa , Yoshiuchi Kazuhiro
Published: February 2025

Background

Individuals with type 2 diabetes and eating disorders must change their eating behaviors, which are often influenced by psychological factors like depression and anxiety. To efficiently assess daily psychological status, the present study aimed to develop computerized adaptive tests (CAT) based on item response theory (IRT).

Methods

Individuals with depression, anxiety disorders, eating disorders, type 2 diabetes, and healthy persons participated in the study. Participants completed six questionnaires, including momentary and most recent one-week depression, anxiety, and positive affect. We selected items meeting the IRT assumptions, applied a graded response model, and conducted CAT simulations.

Results

Across all six questionnaires, the CAT simulations used a smaller number of items and exhibited substantial Pearson’s correlation coefficients exceeding 0.95 between simulated and full item-set mood status estimates. These estimated mood scores demonstrated satisfactory concurrent validity with the Hospital Anxiety and Depression Scale and sufficient discriminant validity between the clinical group and healthy controls.

Conclusion

These findings suggest that these scales offer efficient measurement of the mood status of individuals with an eating disorder or type 2 diabetes.
Gender differences in symptom interactions between problematic smartphone use and social anxiety in adolescents: a network analysis
Authors: Guo Sipu , Zou Xinyuan , Tao Yanqiang , Lv Yichao , Liu Xiangping , Huang Silin
Published: February 2025

Background

Increased prevalence of problematic smartphone use (PSU) in adolescents, results in a cycle of interaction between PSU and social anxiety. However, it is still unknown whether PSU and social anxiety symptoms have interacted among adolescents and whether there are gender differences in these symptoms. Therefore, this study investigated the gender differences in the symptom interactions between PSU and social anxiety via symptom network analysis.

Methods

This study included 2918 adolescents (52.71% boys; M
age = 14.73, SD
age = 1.39) from junior and senior high schools in China. The Mobile Phone Addiction Index and Social Anxiety Scale were used to evaluate symptomatology and networks. Network analysis and network comparison tests were used to determine the network structure, centrality, bridge symptoms and gender differences in the PSU-social anxiety network among adolescents.

Results

The most influential symptoms were “productivity loss” and “afraid of negative evaluation”. “Afraid of negative evaluation” was the bridge through which PSU was related to social anxiety. Gender differences were not found in network strength but occurred in network structure. Although girls reported more social anxiety, boys had a tighter network structure. The correlation between PSU and social anxiety was greater in boys than in girls. The “inability to control craving” was particularly critical for girls, while “feeling anxious and lost” was prominent for boys.

Conclusions

The current study highlights the symptom interactions between PSU and social anxiety among adolescents and the gender differences in network structures. Further intervention that targets “afraid of negative evaluation” may disassociate the interaction between PSU and social anxiety symptoms. In particular, changing girls’ cognitive ability (e.g., inhibition) and boys’ negative emotions are potentially effective means of intervention. The limitations of the cross-sectional design and data-driven methodology necessitate interpreting the results with caution.
Multi-pathway targeted therapy of MASH-HCC using miR-22
Authors: Hu Ying , Setayesh Tahereh , Wei Dongguang , Testerman Trenton , Ji Yutong , Wan Yu-Jui Yvonne
Published: February 2025

Background

The treatment options for hepatocellular carcinoma (HCC) are limited, and there is no effective drug that can improve long-term survival rates. Complicated cocktails consisting of multiple medications with toxicities are frequently used to treat cancer. The current study addresses these challenges.

Methods

The study uses metabolic dysfunction-associated steatohepatitis (MASH)-HCC and HCC mouse models established by transfecting the livers using myr-AKT1, NRasV12, and Sleeping Beauty transposase. AAV8-miR-22 was delivered to MASH-HCC and HCC to study its preventive and therapeutic effects. Spatial transcriptomic profiling revealed the signaling pathways affected by miR-22 according to histological locations.

Results

miR-22 treatment effectively treated MASH-HCC and HCC. Treating mice with miR-22 before tumor initiation prevented oncogenesis. The promising anti-cancer effects were revealed by reduced tumor load, fibrosis, and splenomegaly, extending the survival time. miR-22 treatment generated anti-tumor immunity. The favorable treatment outcomes were accompanied by a reduction in dendritic cells, T and B cells, and plasma cells, which were expanded inside the tumors of MASH-HCC. In all animal trials, miR-22 improved metabolism and reduced glycolysis inside the tumors. Moreover, miR-22 profoundly inhibited extracellular matrix (ECM) and targeted MET, PDGF, tyrosine kinase signaling, and IGF pathways inside the tumors. Furthermore, the roles of miR-22 in blocking collagen formation and cross-assembly of collagen fibrils could be due to miR-22's effects in inhibiting Rho GTPase pathways, revealed at the tumor margin.

Conclusion

miR-22 generates anti-HCC effects by targeting many critical pathways in liver carcinogenesis in cancer and tumorigenic niches, potentially revolutionizing HCC treatment.
Treatment rationale in nutcracker syndrome with concurrent pelvic congestion syndrome
Authors: Steffen Dominik A. , Najafi Arash , Festas Georgios , Binkert Christoph A.
Published: February 2025

The optimal management strategy of nutcracker syndrome is debated, especially in the setting of concurrent pelvic congestion syndrome. In this article, we describe our treatment algorithm as illustrated by four different case scenarios. In our experience, renocaval pressure gradients are often inconclusive, but evaluation of the left renal vein waveform as well as a “test PTA” with evidence of a waist in the balloon can be helpful in unmasking a relevant stenosis. We consider nutcracker syndrome not to be a contraindication for ovarian vein embolization. Decision for simultaneous or sequential stenting should be based on angiographic findings and clinical course.
Patients with anti-PM/Scl-positive and idiopathic inflammatory myopathy resemble anti-synthetase syndrome
Authors: Barbosa Rafaella do Amaral , Shinjo Samuel Katsuyuki
Published: February 2025

Background

Anti-PM/Scl autoantibody has been associated with an overlap between polymyositis (PM) and systemic sclerosis (SSc). However, due to limited studies, the relevance of this autoantibody in patients with idiopathic inflammatory myopathies (IIMs) without SSc was analyzed.

Methods

This single-center retrospective cohort study was conducted between 2004 and 2024. A total of 93 adult patients with IIMs (66 with dermatomyositis and 27 with PM - EULAR/ACR 2017) without SSc were included: 16 anti-PM/Scl(+) and 77 anti-PM/Scl(-). Patients with other types of IIMs, cancer-associated myositis, or overlap myositis, including SSc, as well as those with other myositis-specific and/or myositis-associated autoantibodies were excluded.

Results

The median age, sex distribution, and median follow-up duration were comparable between the anti-PM/Scl(+) and anti-PM/Scl(-) groups. There were no differences in clinical and laboratory characteristics, except for a higher frequency of lung involvement, joint involvement, “mechanics’ hand,” “hiker’s feet,” and Raynaud’s phenomenon, in contrast to a lower frequency of facial rash and “V”-neck sign in patients with anti-PM/Scl(+) than in those with anti-PM/Scl(-) (all P < 0.05). Furthermore, patients with anti-PM/Scl(+) exhibited a higher frequency of disease relapse (68.8% vs. 33.8%), disease activity (50.0% vs. 24.7%), and immunosuppressant use (methotrexate or azathioprine) at the last medical evaluation (all P < 0.05). Severe infection and death rates were comparable between the groups.

Conclusions

Anti-PM/Scl positivity was observed in 17.2% of the sample analyzed in the present study. Patients with this autoantibody present clinical manifestations resembling anti-synthetase syndrome, with increased disease relapse and activity rates.
Selective Therapeutic Potential of a H2O2 Inducible DNA Interstrand Cross-Linker in Anaplastic Thyroid Carcinoma
Authors: Lu Chenghui , Yu Dehao , Wang Xufu , Li Jiao , Zhang Yingying , Wang Congcong , Jia Qiang , Tan Jian , Zheng Wei , Sun Huabing , Meng Zhaowei
Published: February 2025

Objective

We aimed to investigate Hydrogen Peroxide Inducible DNA Interstrand Cross-Linker (HP-ICL) as a targeted therapy for anaplastic thyroid cancer (ATC) due to its higher H2O2 content compared to normal cells.

Methods

In vitro analysis included fluorescence microscopy for H2O2 levels, and exposure of ATC cells to various HP-ICL concentrations followed by assessment of cell viability, apoptosis, cell cycle, and DNA damage using MTT, flow cytometry, and a γH2AX assay. Protein levels related to apoptosis and the PI3K/AKT/mTOR pathway were measured by western blotting. An ATC xenograft mouse model was used to evaluate HP-ICL's in vivo effects.

Results

ATC cells had higher H2O2 levels than normal thyroid cells. HP-ICL treatment caused a dose-dependent decrease in cell viability and an increase in apoptosis, with a slight G2/M phase arrest. A 30 µM HP-ICL treatment doubled γH2AX foci. Bcl-2 levels decreased, while Bax, cleaved-Caspase 3 and PARP increased in a dose-dependent manner. It also inhibited p-PI3K, p-AKT, and p-mTOR. In vivo, HP-ICL significantly inhibited tumor growth while maintaining body weight and without causing organ damage or altering thyroid hormone levels. Additionally, tumor sections exhibited increased TUNEL staining, decreased Ki67 expression, and reduced levels of p-PI3K, p-AKT, and p-mTOR.

Conclusion

HP-ICL significantly inhibited ATC both in vitro and in vivo, suggesting its potential as an effective therapy for ATC.
Small-Scale Institutions in Karen Tei Yamashita's I Hotel
Authors: Strombeck Andrew
Published: February 2025

This article examines tensions between I Hotel's sprawling, experimental form—which appears tailored to the disruptions of the 1960s and 1970s—and its continual return to the stabilizing function of the hotel itself. I Hotel meditates on the problems and possibilities of literary building, within a historical setting that represents the very epitome of anti-institutionalism. Published at a moment—the aftermath of the 2008 crash—when housing insecurity had again emerged as a significant site of activism, I Hotel examines the utopian possibilities latent within small-scale institutions, even as it also acknowledges the real limitations of such institutions. Rife with productive contradictions, I Hotel depicts the hotel as both real and imaginary, singular and multiple, actual and potential. In doing so, Yamashita's novel suggests ways that literary works help readers conceptualize the difficult territory between revolutionary transformation and institutional reform.
Transforaminal Full-Endoscopic Surgery for Lumbar Foraminal Pathologies: A Comparative Clinical Effectiveness Study
Authors: Sugiura Kosuke , Payne Cathryn , Tran Nguyen T. , Leyendecker Jannik , Ogunlade John , LaVanne Mary , Derman Peter B. , Quon Robert , Telfeian Albert E. , Hofstetter Christoph P. ,   on behalf of the Endoscopic Spine Research Group (ESRG)
Published: February 2025

BACKGROUND AND OBJECTIVES:

Full-endoscopic surgery is increasingly used for treating lumbar foraminal pathologies, though the specific indications remain unclear. This study aims to evaluate patient-reported outcomes after transforaminal full-endoscopic spine surgery for various lumbar foraminal conditions.

METHODS:

Multicenter cohort study of patients with intervertebral lumbar foraminal pathology who underwent full-endoscopic decompression at four medical centers. Postoperative patient-reported outcomes, including low back and leg pain as well as Oswestry Disability Index (ODI) scores, were prospectively tracked using a mobile app for 6 months. Six-month outcome measures (patient-reported outcome measures) were used as the primary outcome variable to determine treatment effectiveness regarding various foraminal pathologies.

RESULTS:

A total of 83 patients with a mean age of 57.04 ± 1.63 years were included. The most common operative levels were L4/5 for transforaminal endoscopic discectomies (59.6%) and L5/S1 for endoscopic foraminotomies (58.1%). Endoscopic discectomies resulted in significant improvements in Visual Analog Scale scores for low back pain (from 5.85 ± 0.43 to 3.02 ± 0.41; P < .001), leg pain (from 6.66 ± 0.34 to 3.12 ± 0.57; P < .001), and ODI scores (from 24.39 ± 1.35 to 12.32 ± 176; P < .001). Endoscopic foraminotomies also resulted in significant improvements in Visual Analog Scale scores for low back pain (from 5.58 ± 0.53 to 3.68 ± 0.58; P < .001) and leg pain (from 6.42 ± 0.47 to 4.21 ± 0.58; P < .001), as well as ODI scores (from 19.28 ± 1.41 to 14.67 ± 2.03; P < .01). The amount of improvement was independent of the severity of foraminal stenosis, as determined on preoperative MRI. However, vertical foraminal stenosis was associated with the lowest treatment response rate.

CONCLUSION:

Endoscopic foraminotomies result in clinically meaningful symptomatic improvement for most lumbar foraminal pathologies. However, the effectiveness of decompression surgery for vertical foraminal stenosis is limited and requires further investigation.
Role of Minimally Invasive Spine Surgery in Spine Oncology
Authors: Newman W. Christopher , Bilsky Mark H. , Barzilai Ori
Published: February 2025

The application of minimally invasive spine surgery (MISS) in degenerative spine disease and deformity has seen rapid growth in the past 20 years. Building on this experience, such methods have been adopted into spine oncology in the past decade, particularly for metastatic disease. The impetus for this growth stems from the benefits of surgical decompression combined with radiation treatment in patients with metastatic disease in conjunction with the need for less morbid interventions in a patient population with limited life expectancy. The result of these two realizations was the application of minimally invasive techniques for the treatment of spine tumors including re-establishment of spinal stability, decompression of the spinal cord or nerve roots, and restoration of spinal alignment. Technological advancement and improvement in biomaterials have allowed for durable stabilization with short constructs even for patients with poor bone quality. The implementation of navigation and robotic capabilities has transformed MISS by streamlining surgery and further reducing the surgical footprint while laser ablation, endoscopy, and robotic surgery hold the potential to minimize the surgical footprint even further. MISS for intradural tumors is commonly performed, while the role for other primary tumors has yet to be defined. In this article, we describe the evolution of and indications for MISS in spine oncology through a retrospective literature review.
How Do Robotics and Navigation Facilitate Minimally Invasive Spine Surgery? A Case Series and Narrative Review
Authors: Quiceno Esteban , Soliman Mohamed A. R. , Khan Asham , Mullin Jeffrey P. , Pollina John
Published: February 2025

BACKGROUND AND OBJECTIVES:

Image guidance has transformed minimally invasive spine surgery (MISS), allowing for safer procedures without excessive bony exposure and reducing radiation exposure for the surgical team. Robotic platforms have enhanced the benefits of navigation by providing high precision and accuracy. Here we describe a case series to demonstrate the accuracy and low complication rates of real-time image-guided robotic-assisted (RA) MISS at a tertiary referral center. In addition, we performed a narrative review on how robotics and navigation facilitate MISS.

METHODS:

A retrospective chart review was conducted to obtain data for patients who underwent RA lumbar fusions with real-time navigation for degenerative lumbar pathology between September 1, 2021, and January 1, 2024. The Mazor X Stealth Edition (Medtronic) robotic platform was used. The accuracy of screw placement was determined according to Gertzbein-Robbins classification. Intraoperative and postoperative complication rates up to 90 days were recorded. Intraoperative variables and length of stay were compared between open and percutaneous groups.

RESULTS:

A total of 247 patients underwent insertion of 1156 pedicle screws. The mean patient age was 61.1 ± 11.5 years. The mean total operative time was 195.1 ± 80.8 minutes. The mean operative time per screw was 4.2 ± 1.4 minutes, with a mean of 4.6 ± 1.4 screws per case. The mean fluoroscopy time per screw was 6.4 ± 6.2 seconds. Eighty-five patients (34.4%) underwent open RA pedicle screw placement, and 162 (65.6%) underwent percutaneous RA pedicle screw placement. No differences in operative time, length of stay, fluoroscopy time, and surgical complications were found between groups. Intraoperatively, 2 patients (0.8%) experienced complications and 4 patients (1.6%) developed complications within 90 days. Screw placement accuracy was perfect in 1126 screws (97.4%) and clinically acceptable in 30 screws (2.6%). These results were consistent with those reported in the literature.

CONCLUSION:

Robotic platforms have further enhanced navigation benefits by providing high precision and accuracy, with low complication rates.
Effect of non-linear thermal radiation and Cattaneo-Christov heat and mass fluxes on the flow of Williamson hybrid nanofluid over a stretching porous sheet
Authors: Tsegaye Asfaw , Haile Eshetu , Awgichew Gurju , Dessie Hunegnaw
Published: February 2025

Background Hybrid nanofluids, consisting of two distinct nanoparticles dispersed in a base fluid, are widely used in industries requiring enhanced heat and mass transfer, such as cooling systems and heat exchangers. These fluids improve thermal conductivity and fluid dynamics, leading to better heat management and energy efficiency. This study investigates the combined effects of non-linear thermal radiation, Cattaneo-Christov heat and mass fluxes, and other factors on the three-dimensional flow, heat, and mass transfer of a Williamson hybrid nanofluid. The flow occurs over a stretching porous sheet subjected to an external magnetic field, Joule heating, chemical reactions, and heat generation. Methods Copper (Cu) and aluminum oxide (Al₂O₃) nanoparticles are suspended in ethylene glycol (C₂C₆O₂) to form the hybrid nanofluid. The governing partial differential equations are transformed into ordinary differential equations using similarity transformations and solved numerically with MATLAB’s bvp4c solver. The study examines various parameters, including stretching ratio, nanoparticle volume fraction, and relaxation times for concentration and thermal effects. Results are validated against existing literature. Results The findings reveal that a higher stretching ratio reduces velocity, temperature, concentration profiles, and local Nusselt and Sherwood numbers, while also lowering skin friction and secondary velocity. Increasing nanoparticle volume fraction decreases velocity and temperature profiles but enhances skin friction, local Nusselt, and Sherwood numbers. Concentration profiles decline with higher concentration relaxation time, while temperature increases with longer thermal relaxation time. Conclusions In conclusion, Cu−Al₂O₃/C₂C₆O₂ hybrid nanofluids demonstrate superior heat and mass transfer capabilities compared to mono-nanofluids. The performance is significantly influenced by parameters such as nanoparticle volume fraction, relaxation times, and the stretching ratio, providing valuable insights for heat and mass transfer applications.
A structured dataset of the federalist society’s public engagements
Authors: Topaz Chad M.
Published: February 2025

Background The Federalist Society, a leading conservative legal organization, has played a significant role in shaping the American judiciary for decades. Despite its influence, comprehensive empirical data on the organization remains scarce. We address this gap by systematically documenting 20,205 public events hosted by the Society from 1984 to 2024, with substantive coverage from 2007 onward. Methods Following ethical best practices in data collection and ownership, we gathered event metadata—including titles, dates, locations, sponsors, topics, and speakers—via web scraping from the Federalist Society’s archives. The dataset is structured to facilitate analysis of event trends, co-speaking networks, and thematic shifts over time. To ensure data integrity, we performed validation, deduplication, and cleaning, resulting in a well-structured, high-quality dataset. Conclusions This dataset provides an empirical foundation for examining the Federalist Society’s role in legal discourse. It is a resource for scholars in law, political science, sociology, gender studies, network science, and computational social science, enabling investigations into key themes of discussion, event participation patterns, demographic diversity, professional backgrounds, and more. Researchers can use it to study institutional influence, legal networks, and the evolution of conservative legal thought.
Refractory Coeliac Disease: Diagnosis, Treatment, and Emerging Therapies
Authors: Starzyk Agnieszka , Charzewski Piotr
Published: February 2025

Coeliac disease (CD) is a chronic immune-mediated disorder triggered by gluten ingestion in genetically predisposed individuals, leading to intestinal damage, malabsorption, and systemic complications. Although traditionally considered a gastrointestinal disorder, CD is now recognized as a multisystem condition with neurological, musculoskeletal, endocrine, and cardiovascular manifestations. Despite advancements in diagnostic tools, the disease remains underdiagnosed due to its diverse clinical presentations.
The global prevalence of CD is approximately 1%, with increasing incidence linked to improved screening and environmental factors. Diagnosis involves serological testing, histological examination, and, in select cases, genetic screening. While strict adherence to a gluten-free diet (GFD) is currently the only effective treatment, many patients face dietary compliance challenges, nutritional deficiencies, and persistent symptoms, necessitating further investigation for refractory CD.
Findings highlight that while GFD remains the cornerstone of treatment, adherence difficulties and ongoing symptoms in some patients require alternative interventions. Research into immune modulation, gut microbiota therapies, and intestinal permeability regulation is ongoing, with promising developments for non-dietary treatment options.
Research on police physical training based on virtual reality technology
Authors: Du Yang
Published: February 2025

With the acceleration of science and technology innovation, Virtual Reality technology (VR) has been widely used in many fields. At the level of police physical training, VR provides technical support for the innovation of traditional training mode by virtue of the characteristics of environmental simulation, process controllability and risk avoidance. This study focuses on the practical application of VR technology in police physical training, and systematically demonstrates its technical adaptability, implementation path and optimization direction. Analyze its technical advantages, specific application methods, as well as the problems and challenges faced in this field. The research shows that the technology can effectively simulate the actual combat environment, promote the coordinated development of the stress response and psychological adjustment ability of the trainees, and reduce the equipment loss and time cost, which has important practical value in promoting the modernization of the police training system.
Otorynolaryngolodzy – samodzielni pracownicy nauki w polskim Lwowie
Authors: Kierzek Andrzej
Published: February 2025

W pracy w skrócie przedstawiono drogi życiowe, zawodowe i naukowe otorynolaryngologów, którzy zdobyli tytuły naukowe, ordynując na terenie Lwowa w pierwszych czterech dekadach XX w. oraz w innych ośrodkach po zakończeniu II wojny światowej. Byli to: Tadeusz Ceypek (1904-1990) – organizator otolaryngologii na Górnym Śląsku i Śląsku Opolskim; Jan Danielewicz (1903-1982) – twórca otolaryngologii dziecięcej polskiej i światowej; Antoni Dobrzański (1893-1953) – założyciel Kliniki Otolaryngologicznej w powojennej Warszawie; Wiktor Jankowski (1905-1988) – otolaryngolog, audiolog, antropolog, współtwórca otolaryngologii wrocławskiej; Antoni Jurasz sen. (1847-1923) – jeden z twórców laryngologii światowej, pionier tej specjalności w Heidelbergu, we Lwowie i w Poznaniu; Stanisław Kossowski (1909-1989) – otolaryngolog we Wrocławiu, twórca metod medycyny fizykalnej w rynolaryngologii; Wacław Kuśnierczyk (1908-1997) – otolaryngolog i onkolog na Górnym Śląsku oraz Teofil Zalewski (1872-1953) – założyciel klinicznej otolaryngologii we Lwowie i Wrocławiu. Jurasz otrzymał veniam legendi w 1876 w Heidelbergu, Zalewski – w 1908, Dobrzański – w 1929, a Jankowski i Ceypek – w 1939 r.; wszyscy czterej we Lwowie. Pozostali habilitowali się w okresie powojennym: Kossowski w 1951 r. we Wrocławiu, Danielewicz – w 1954 w Warszawie, a Kuśnierczyk – w 1955 w Gliwicach. Wszyscy oni odegrali znaczącą rolę w rozwoju polskiej otorynolaryngologii w Polsce po II wojnie światowej.
Piotr Lenartowicz SJ, Vivere et intelligere. Wybrane prace Piotra Lenartowicza SJ wydane z okazji 75-lecia jego urodzin. Red. Jolanta Koszteyn. Wyższa Szkoła Filozoficzno-Pedagogiczna Ignatianum. Wyd. WAM, Kraków 2009, 832 ss.
Authors: Kupczak Rafał Antoni , Szkutnik Dariusz Adam
Published: February 2025

W 2022 r. minęła dekada od śmierci ks. prof. Piotra Lenartowicza SJ, wybitnego krakowskiego filozofa przyrody i lekarza specjalizującego się w neurofizjologii. Z tej okazji warto przypomnieć jego dorobek naukowy, zamieszczony w obszernym zbiorze prac Vivere et intelligere opublikowanym w 2009 r. przez Wydawnictwo WAM, z okazji 75-lecia Jego urodzin. Publikacja ta, licząca ponad 800 stron, stanowi ważne źródło wiedzy na temat filozofii przyrody ożywionej. Redaktorka zbioru dr Jolanta Koszteyn wraz ks. prof. Romanem Darowskim SJ (autor biografii) oraz z dr. hab. Zbigniewem Wróblewskim (przeprowadził wywiad) wprowadzają czytelnika w świat myśli i badań Piotra Lenartowicza. Prace zostały podzielone na trzy rozdziały, które odnoszą się do głównych zainteresowań filozofa: dynamiki form żywych, paleobiologii oraz problematyki poznania. Lenartowicz prowadził badania w duchu obiektywizmu i pluralizmu ontycznego, opierając swoje odkrycia na arystotelesowsko-tomistycznej metodzie. Jego badania dotyczące całościowości i totipotencjalności procesów biologicznych, a także zjawiska epigenezy wprowadziły pewną nową jakość do filozofii przyrody ożywionej. W swoich pracach podejmował także tematy paleoantropologiczne, analizując ewolucję człowieka i status taksonomiczny australopiteków. Lenartowicz kładł nacisk na epistemologię; traktował ją jako klucz do rozstrzygania kontrowersji filozoficznych. Jego dorobek jest ważnym punktem odniesienia dla współczesnych badań nad biologią i filozofią. Prace Lenartowicza nie tylko rzucają światło na problemy współczesnej nauki, ale także inspirują kolejne pokolenia badaczy do poszukiwania głębszych odpowiedzi na fundamentalne pytania dotyczące życia.
Utopie i światy alternatywne w multimediach, crossmediach i transmediach (wolność, odpowiedzialność, bezpieczeństwo, dobrostan)
Authors: Jastrzębski Jerzy
Published: February 2025

UTOPIAS AND ALTERNATIVE UNIVERSES IN MULTIMEDIA, CROSSMEDIA AND TRANSMEDIA (FREEDOM, RESPONSIBILITY, SECURITY, WELL-BEING)This article deals with both the relationship between multimedia, crossmedia and transmedia, and the significance of values such as freedom, responsibility, security and wellbeing in contemporary media discourse. It explores how the media often distorts and manipulates the truth.
Liryka konwersacyjna w funkcji narratywu – ideologem
Authors: Pandev Dimitar
Published: February 2025

CONVERSATIONAL LYRICYSM AS A NARRATIVE FUNCTION – IDEOLOGEME
The conversational lyric (an expression that we take from the Makjej Kavka’s study on the poetry of Aco Shopov and adapt it to poetry with an emphasized communicative function) opens new multimedia forms of public performance in front of a wide auditorium with a clearly emphasized contact (phatic), but also has a propaganda function, most often for political purposes. This especially applies to poetry whose main purpose was, and remains, the preservation of historical or cultural information, which could not be preserved in any form other than poetic and which can be actualized at any time in completely different social conditions. In the Macedonian poetry, this refers, first of all, to the poems formed during the Ilinden uprising (the so-called “teacher’s poetry” in which the works of the revolutionaries, like Goce Delchev and others are sung), during the National Liberation War, the poem “Ochi” by Aco Shopov; but also in the later period of the development of the modern Macedonian poetry, the poems “Teshkoto” and “Molitva” by Blaze Koneski, etc. Most of these songs today are especially actualized relevant during elections and other political campaigns. This paper presents the actualization of the poems that in specific current political events acquire the function, above all, of a political narrative (ideologeme), especially if it is about pre-election marketing (poems to Blaze Koneski in the pre-election period in 2016), or marking historical events and their celebration followed by multimedia forms that include interpreting poetry (October 11 – Day of the Uprising of the Macedonian people and October 23 – Day of the Macedonian Revolutionary Struggle) in 2023.
Odpowiedzialność rozszerzona jako czynnik niezbędny w walce z dezinformacją
Authors: Bąkowicz Katarzyna
Published: February 2025

EXTENDED RESPONSIBILITY AS A NECESSARY FACTOR IN THE FIGHT AGAINST DISINFORMATION: ANALYSIS OF OWN RESEARCH
When there were only traditional media such as press, radio or television, communication was structured and predictable. The emergence of the Internet and social media has not only changed us as users, but has significantly increased the amount of information, thus leading to chaos, an overabundance of content and an increase in the amount of misinformative materials. People whose professional activity is related to communication not only have a higher level of knowledge about disinformation, but also a different perspective on the issue of social responsibility for the quality of information. This shows how we can eliminate the thoughtless distribution of clickbyte content, the presence of which destroys the information ecosystem, lowering its quality, and start building a new one, free from half-truths and distortions. The concept of extended responsibility is a response to a challenge we have been struggling with for a long time, which provides opportunities for real improvement in the quality of communication. It is based on broadening perspective without limiting freedom, thus providing opportunities to use the potential of communication in all its dimensions.
Polska prasa podziemna wobec powstania w getcie warszawskim
Authors: Beround Alan
Published: February 2025

THE POLISH UNDERGROUND PRESS IN THE FACE OF THE WARSAW GHETTO UPRISING
The Polish underground press, representing a variety of views and ideologies, had a diverse approach to the Warsaw Ghetto Uprising. In their articles, they often spoke favorably about the spirit of Jewish resistance in the face of Nazi cruelty, seeing this act of desperation and courage as an act of national solidarity in the fight for common values. The press also emphasized the political context, analyzing the situation as part of the broader fight for Poland’s independence.
Obraz powstania zabajkalskiego w tradycji, historii, legendzie oraz prasie rosyjskiej
Authors: Łonak-Grzybczak Klaudia
Published: February 2025

THE IMAGE OF THE SIBERIAN UPRISING IN TRADITION, HISTORY, LEGEND AND THE RUSSIAN PRESSThe Zabaikal Uprising is the aftermath of the January Uprising, after the end of which nearly 20,000 insurgents as well as active supporters of the last great independence uprising in the 19th century were sent to Siberian exile by the tsarist authorities. Building the “Baikal Road,” the exiles decided to launch an uprising with the goal of either leading a rebellion of all-Russian proportions or, just as likely, organizing the largest possible group of people to escape to China.The uprising was quickly and bloodily suppressed. As a result of repression, the leaders of the uprising were executed while other participants were severely punished. These events did not resonate in the foreign press, which preferred to deal with the Prussian-Austrian war rather than another tragic uprising of the Siberian Legion of Free Poles. Some echoes of the uprising, however, found their way into the Russian press. Using available materials, the author of the paper (publication) intends to present the position of the Russian press towards the Polish issue in the area indicated above.
The Effect of On-the-Job Experience on Base-Rate Neglect: Evidence from Medical Professionals
Authors: Araujo Felipe A. , Chabris Christopher F. , Meyer Michelle N.
Published: February 2025

We study the effect of on-the-job experience on base-rate neglect, which is a common bias in assessing conditional probabilities. We do so by carrying out experiments with medical professionals, who are routinely exposed to conditional-probability problems in the form of diagnostic tests, and nonmedical professionals, who are not. As such, medical workers with more years of experience will have had more exposure to base-rate type problems than nonmedical workers with similar years of experience. We estimate the effect of on-the-job experience by comparing the answers of more or less experienced professionals in both the medical and nonmedical domains. Although the incidence of the bias is high for both groups and all levels of experience, we find that more experienced medical workers (a) have lower rates of perfect base-rate neglect (i.e., completely ignoring the base rates), (b) provide more accurate posterior estimates, and (c) adjust their estimates more in response to changes in the base rates. We observe no such difference for nonmedical workers. We conduct a number of robustness checks and consider possible mechanisms, such as education, job or survey attrition, selectivity into medical professions, and experience with false positives. Our results suggests that on-the-job experience mitigates, but does not eliminate, base-rate neglect.

This paper was accepted by Lauren Cohen, finance.

Funding: This work was supported by Lehigh University [FRG Grant].

Supplemental Material: The online appendices and data files are available at https://doi.org/10.1287/mnsc.2024.05461 .
Journal scan
Authors: Welyczko Nikki
Published: February 2025

A brief overview of recently published articles on gastroenterology, hepatology and stoma care
A Case Report of Neisseria sicca Endocarditis in a Patient with Tissue Aortic Valve: Favorable Outcome Following Prompt Multidisciplinary Team Management
Authors: Jamil Husam , Ezzo Talal , Doumi Aymen , Diab Zeinab Abdallah Elias , Saleem Anum
Published: February 2025

Neisseria sicca is commonly found in oral flora and is usually deemed harmless. Neisseria sicca is very rarely associated with infective endocarditis and has a high mortality rate with it. We present a case of infective endocarditis in a 57-year-old male who presented with fever, lethargy, and reduced mobility and was admitted to an acute medical unit of a UK district general hospital. Serial blood cultures grew Neisseria sicca and transoesophageal echocardiography confirmed vegetation on the aortic valve. As per microbiology advice, his antibiotic treatment was adjusted to oral ciprofloxacin and intravenous ceftriaxone for 6 weeks given this organism’s sensitivity. The cardiology team arranged outpatient appointments for long-term follow-ups. Involving acute medicine, microbiology, and cardiology teams as part of a multidisciplinary team (MDT) led to good clinical outcomes and patients remained alive and well on follow-ups. So far only 27 cases have been documented and we think our work would increase insights into management strategies for this condition particularly the utilization of the MDT approach.
THE INTEGRATION OF SWOT- FUZZY AHP GROUP (FAHPG) FOR BUILDING STRATEGIES OF IMPLEMENTATION SOCIAL-ECONOMICS: A CASE STUDY IN DAK NONG PROVINCE, VIETNAM
Authors: LE DINH CANH
Published: February 2025

In this study, the objective is to integrate SWOT and the Fuzzy AHP Group (FAHPG) to propose strategies in order of weighted priority, from highest to lowest for socio-economic development. The process is as follows: First, the SWOT framework is applied to analyze strengths (S), weaknesses (W), opportunities (O), and threats (T). Next, FAHPG is used to calculate the weights of the level 1 factors (SWOT objectives) and level 2 factors (SWOT factors). Finally, strategies are ranked and prioritized by calculating the weights of the relationships between level 2 factors (SWOT factors) and the proposed strategies (SO1, SO2, SO3, WO1, WO2, ST1, ST2, WT1, WT2, WT3). The calculated results identify strategies with varying weights. Without following this method, the strategies would be implemented based on groups such as SO (SO1, SO2, SO3), WO (WO1, WO2), ST (ST1, ST2), and WT (WT1, WT2, WT3), rather than implementing individual strategies separately according to their priority, from highest to lowest (SO3: 0.117 > ST2: 0.103 > WT3: 0.102 > SO2: 0.101 > WT2: 0.100 > ST1: 0.098 > WT1: 0.098 > WO2: 0.097 > SO1: 0.092 > WO1: 0.090). The study in Dak Nong province involved the participation of planners, ensuring that the results have a high degree of feasibility.
SENSATION SEEKING AND POSTTRAUMATIC STRESS LEVELS IN POLISH SOLDIERS FIGHTING IN AFGHANISTAN
Authors:   Military Institute of Medicine, Warsaw, Poland, Zbyszewski Maciej , Terelak Jan ,   Institute of Psychology, Cardinal Stefan Wyszynski University in Warsaw, Warsaw, Poland
Published: February 2025

Introduction: The central aim of the present study was to address whether sensation seeking traits are related to severity of posttraumatic stress disorder symptoms (PTSD) in soldiers conducting military operations in Afghanistan, and whether this effect is moderated by selected personality traits and strength of traumatic stimulus. The study was drawn upon the Regulatory Theory of Temperament by Strelau, in reference to which it can be assumed that people characterized by both the highest and the lowest levels of sensation seeking traits would be at greater risk of suffering from PTSD symptoms.

Methods: 125 Polish soldiers of the Armored Cavalry Brigade who took part in military mission in Afghanistan in 2013/2014 filled in the following psychological questionnaires: PTSD Questionnaire (PTSD – C Scale); Impact of Event Scale (IES); Sensation Seeking Scale (SSS – V); Impulsiveness Questionnaire (IVE); Eysenck Personality Questionnaire Revised (EPQ-R); Combat Exposure Scale (CES).

Results: Results indicated no direct relationship between sensation seeking and the severity of posttraumatic stress among Polish soldiers participating in combat operations in Afghanistan. However, after controlling for the effect of neuroticism and impulsiveness in the studied group of soldiers, the sensation seeking appeared to be a strong predictor of PTSD symptoms.

Conclusion: The study provided information on the feature of sensation seeking which regardless of its severity should not be treated as a predictor of emotional disturbances. However under certain conditions created by personality variables the relationship between the sensation seeking and symptoms of posttraumatic stress can occur. Possible explanatory mechanisms refer to the urge to immediate reduction the emotional tension. Among the personality types, individuals with high anxiety and high impulsivity would be most susceptible to the consequences of traumatic stress.
KEY ASPECTS IN LARYNGOLOGICAL CARE OF PATIENTS AFTER LARYNGECTOMY WITH RECURRENCE OF LARYNGEAL CANCER
Authors:   Department of Otolaryngology CMKP, Mazovian “Bródnowski” Hospital in Warsaw, Warsaw, Poland, Sobczyk Krystyna , Dżaman Karolina ,   Department of Otolaryngology CMKP, Mazovian “Bródnowski” Hospital in Warsaw, Warsaw, Poland, Wachulski Bartosz ,   Department of Otolaryngology CMKP, Mazovian “Bródnowski” Hospital in Warsaw, Warsaw, Poland, Szabelska Bożena ,   Department of Otolaryngology CMKP, Mazovian “Bródnowski” Hospital in Warsaw, Warsaw, Poland, Jowik Rafał ,   Department of Otolaryngology CMKP, Mazovian “Bródnowski” Hospital in Warsaw, Warsaw, Poland
Published: February 2025

Introduction: The larynx is the most common location of malignant tumors of the head and neck region. Approx. 90% of malignant tumors of the larynx are squamous cell carcinomas. The patient after treatment for laryngeal cancer has problems with the basic functions of life, i.e. breathing, eating, speaking, disorders of smell and taste and also the sense of aesthetics of their own body. Therefore, caring for a laryngectomized patient requires a multidisciplinary approach. Every patient undergoing laryngectomy undergoes a process of social rehabilitation, both in terms of family, work and community life.

Purpose: The purpose of this article was to present current knowledge on the care of patients with recurrent laryngeal cancer, detailing the role of individual members of the multidisciplinary team

Methods: A review of current medical knowledge.

Discussion and conclusions: A patient who successfully completed treatment for laryngeal cancer requires the care of a team of doctors from different specialties. In addition to an oncologist, laryngologist, internist, family medicine doctor and palliative care physician, a psychologist plays a significant role in the treatment process.
Critiquing the categorisation and measurement of disability, and family and domestic violence: a scoping review
Authors: Walter Brontё , Watts Lynelle , Waters Rebecca , Chung Donna
Published: February 2025

Women with disability (WWD) are considerably more likely to experience family and domestic violence (FDV) victimisation than women generally, however, estimates vary widely. This article considers the extent to which studies are able to apply intersectional understandings of FDV against WWD to the categorisation and measurement of the issue. A literature review of ProQuest and Scopus was undertaken in 2021. Peer-reviewed articles, books and book chapters published within five years were included for review. Studies were chosen for their explicit focus on both women with disability and domestic violence. Forty-three studies were included for analysis, 16 of which were prevalence studies. Findings indicated that studies were generally positivist, lacked theorising of findings, and gathered limited perpetrator data. Methodological choices also impacted the ability of studies to capture nuanced data which is required for meaningful social and political change. Considerations for future studies of prevalence are discussed.
Protest embodied: enacting the goal, resisting the clothing of the state
Authors: Beckwith Karen
Published: February 2025

This article identifies protests by organized women concerning state-imposed clothing requirements and bans. Relying on secondary sources, government reports, and newspaper accounts, the article analyzes women’s embodiment of protest in three mass actions around the globe: protests against mandatory hijab wearing in Iran, and global “Slut Walks” and “Take Back/Reclaim the Night” marches. The article locates these campaigns in women’s movement activism and shows how activist women, protesting for their goals, embody and hence achieve their goals in these campaigns. In this regard, such protests involve more than vestments: these protests assert women’s citizenship equality with men and demonstrate that achieving a goal that challenges the state is possible. The article concludes with speculations about state responses to women’s embodied protest.