bluuebunny/crossref_metadata_2025 huggingface dataset:
Intracranial fungal Cladophialophora bantiana infection in a nonimmunocompromised patient: A case report and review of the literature
Authors: Kilbourn Kent J. , Green Jaquise , Zacharewski Nicholas , Aferzon Joseph , Lawlor Michael , Jaffa Matthew
Published: April 2022

Background:

Cladophialophora bantiana is a dematiaceous fungus that rarely infects the central nervous system (CNS). It is associated with a mortality rate of over 70% despite treatment.

Case Description:

An 81-year-old female with a remote history of renal cell carcinoma presented with progressive headache and an expressive aphasia for 3 days. Computed tomography imaging revealed a left frontotemporal mass with surrounding vasogenic edema. A left frontotemporal craniotomy was performed and cultures revealed C. bantiana. The initial management with IV voriconazole was unsuccessful and the patient had a recurrence of the cranial infection and developed pulmonary abscesses. Following the addition of oral flucytosine, the patient showed a significant improvement with a complete radiographic resolution of both the cranial and pulmonary lesions.

Conclusion:

C. bantiana involving the CNS is a rare and often fatal disease. Surgical management along with standard antifungal treatment may not provide definitive therapy. The addition of flucytosine to IV voriconazole resulted in a positive outcome for this patient who is alive, living independently 1 year from the original diagnosis. In this rare fungal infection, standard antifungal treatment may not provide adequate coverage and the utilization of additional therapy may be required.
Spinal epidural abscess due to acute pyelonephritis
Authors: Scalia Gianluca , Marrone Salvatore , Paolini Federica , Palmisciano Paolo , Ponzo Giancarlo , Giuffrida Massimiliano , Furnari Massimo , Iacopino Domenico Gerardo , Nicoletti Giovanni Federico , Umana Giuseppe Emmanuele
Published: April 2022

Background:

Spinal epidural abscesses are rare and are misdiagnosed in up to 75% of cases. Fever, back pain, and neurological deficits are part of the classical triad. Here, the authors report a patient with a L2–L5 spinal epidural abscess with the left paravertebral extension attributed to acute pyelonephritis.

Case Description:

A 54-year-old female presented with persistent low back pain and lower extremity weakness accompanied by paresthesias. Previously, she had been hospitalized with the left acute pyelonephritis. The lumbosacral MRI documented a T12/L5 anterior epidural abscess with ring enhancement on the contrast study; the maximum diameter of the abscess at the L2–L3 level contributed to severe cauda equina compression. She underwent a L2/L4 decompressive laminectomy with drainage of the intraspinal/extradural and paravertebral components. Intraoperative microbiological sampling grew Staphylococcus aureus for which she then received targeted antibiotic therapy. Fifteen days later, she was walking adequately when discharged.

Conclusion:

Thoracolumbar epidural abscesses are rare. They must be considered among the differential diagnoses when patients present with acute back pain, fever, and new neurological deficits following prior treatment for acute pyelonephritis.
Analytical Chemistry in Industrial Food Research
Authors: Fay Laurent B. , Horman Ian
Published: April 2022

Because of the complexity of food matrices, analytical chemistry has a key role to play in the elucidation of food composition, food stability and its behaviour during processing. In this paper, the application of various analytical techniques (e.g., near IR spectroscopy, electronic
nose technology, nuclear magnetic resonance and mass spectrometry) are discussed.
Enantioselective Chromatography: an Essential and Versatile Tool for the Analytical and Preparative Separation of Enantiomers
Authors: Francotte Eric R.
Published: April 2022

Chromatography on chiral stationary phases and electrophoresis in the presence of chiral selectors have become essential tools for the determination of enantiomeric purity in connection with synthesis and with biological studies of chiral molecules. Moreover, the chromatographic resolution
of racemates on a preparative scale compels increasing recognition as alternative to 'preparing' pure enantiomers. The state-of-the-art of enantioselective chromatography in the analytical and preparative field is reviewed with particular emphasis on the achievements carried out in Switzerland.
Quantifying the Dynamics of Pesticides in Natural Waters
Authors: Müller Stephan R.
Published: April 2022

A variety of trace analytical methods (solid-phase and liquid-liquid extraction, HPLC and GC-MS) for quantitatively assessing the input and behavior of pesticides and their metabolites (i.e., triazines, acetamides, phenoxy acids and organotin compounds) in natural waters and
sediments are presented. The results of field studies illustrate the analytical methods performance such as simultaneous determination of compounds with different polarities, low detection limits, and high precision and accuracy.
Feed Stuffs Analysis at the Swiss Federal Research Station for Animal Production (RAP), Posieux : Die Futtermittelanalytik an der Eidgenössischen Forschungsanstalt für Nutztiere (RAP) in Posieux
Authors: Schmitter Beat M. , Rihs Toni
Published: April 2022

Agricultural research and associated control or service activities are carried out, in Switzerland, in six federal research stations. The Swiss Federal Research Station for Animal Production (RAP) focuses on the optimal conversion of feed stuffs into milk and meat, taking into
account animal requirements as well as ecological and economic considerations. The station also operates the official Swiss feed stuffs control laboratory. Its analytical chemistry section carries out over 100 000 tests/year, using chemical, physical and microbiological methods, and authenticity
procedures based on molecular biology. Sample diversity combined with a multitude of test incentives requires a broad range of state-of-the-art methods for the determination of nutrients, minerals, noxious substances and residues. Evaluating, adapting, and validating analytical methods and
testing equipment, are therefore essential tasks of this section. Being accreditaded according to European standards (EN 45001), the laboratory has furthermore to meet the high quality management criteria.
MALDI-MS at the Ingenieurschule Burgdorf: The Technique, Some Applications and Expected Benefits for the Education in Modern Analytical Chemistry
Authors: Schär Martin
Published: April 2022

Analytical chemistry is changing rapidly, new methods are developed and introduced in the analytical laboratories. Parallel to this progress, the chemical industry is undergoing pronounced changes: it is focusing more and more on the life sciences.Consequently, the importance of analytical biochemistry is increasing.The educational system has to keep pace with these developments and has to integrate the new methods, which are or will be tools in analytical laboratories, into the analytical chemistry courses.Therefore, we were looking for an appropriate method which would allow us to face these challenges in analytical education at the Ingenieurschule (college of engineering) Burgdorf. With the recent acquisition of a matrix-assisted laser desorption mass spectrometer (MALDI-MS), a new analytical technique which has the potential to fulfill our requirements can be offered to the chemistry students.This contribution presents some analytical applications such as the sequence analysis of a modified oligonucleotide, the characterization of a non-covalently bound antigen-antibody complex as well as the analysis of a synthetic polymer and copolymer. Projects how to implement the method in the analytical chemistry course and the expected benefits for the students are discussed.
Dimensionless parameters and numbers controlling PFAS transport in unsaturated porous media
Authors: Jiao Wentao , Li Xiaoxing , Zhan Mingxiu , Wu Rui , Shan Yongping , Zhang Chenchen , Yin Yongguang , Giesy John
Published: April 2022

Per- and polyfluoroalkyl substances (PFAS) is the emerging contaminants of critical concern. Comprehensive understanding of the transport and fate of PFAS in the vadose-zone, a type of water-unsaturated porous media, is key to determination of the risks of the PFAS contamination in the subsurface and to the development of the effective remediation strategies. PFAS transport in the unsaturated porous media is a complex process. In order to disclose the main factors controlling the PFAS transport in unsaturated porous media, we develop the theoretical model based on the dimensionless governing equations for the transient water flow and PFAS transport. The effects of the dimensionless parameters and numbers on the PFAS transport in 2D unsaturated porous media are uncovered based on the second order accurate finite volume method. We find that the retardation numbers and the dimensionless parameters relevant to the properties of porous media as well as the relation between the surface tension and the PFAS concentration play an important role in the PFAS transport in the unsaturated porous media. The effects of the Péclet numbe, Damköhler numbers, and fraction of instantaneous sorption are not significant, however. These findings provide a better understanding of the PFAS transport in vadose zone.
Bioinspired Asymmetric Total Synthesis of Emeriones A–C
Authors: Jänner Sven , Isak Daniel , Li Yuli , Houk K. N. , Miller Aubry
Published: April 2022

We report an asymmetric bioinspired total synthesis of the fungal metabolites emeriones A–C via stereoselective late-stage epoxidation or endoperoxidation of two bicyclo[4.2.0]octadiene diastereomers. The central bicyclic scaffold is synthesized in an 8pi/6pi electrocyclization cascade of a stereodefined (E,E,Z,Z,E)-pentaene, which contains the fully assembled and unprotected side chains of the natural products. The pentaene is constructed convergently through Stille cross-coupling of two similarly complex polyenes. The anti-aldol side chain of the emeriones is made using a Paterson-aldol approach, and the epoxide of the dioxobicyclo[3.1.0] side chain is synthesized via ring-closure onto an oxidized para-methoxyphenyl acetal. Our total synthesis has enabled the revision of the structure of emerione C and the synthesis of a “missing” family member, which we hereby call emerione D. DFT calculations indicate the two methyl groups that reside on the cyclobutene ring are critical for the stereochemical outcome of 8pi/6pi electrocyclization.
Hydrogen evolution mitigation in iron-chromium redox flow batteries via electrochemical purification of the electrolyte
Authors: Wan Charles , Rodby Kara , Perry Mike , Chiang Yet-Ming , Brushett Fikile
Published: April 2022

The redox flow battery (RFB) is a promising electrochemical energy storage solution that has seen limited deployment due, in part, to the high capital costs of current offerings. While the search for lower-cost chemistries has led to exciting expansions in available material sets, recent advances in RFB science and engineering may revivify older chemistries with suitable property profiles. One such system is the iron-chromium (Fe-Cr) RFB, which utilizes a low-cost, high-abundance chemistry, but the poor Cr redox reaction kinetics and high hydrogen evolution reaction (HER) rates challenge efficient, long-term operation. Of late, renewed efforts have focused on HER mitigation through materials innovation including electrocatalysts and electrolyte additives. Here, we show electrochemical purification, where soluble contaminants are deposited onto a sacrificial electrode prior to cell operation, can lead to a ca. 5× reduction in capacity fade rates. Leveraging data harvested from prior literature, we identify an association between coulombic efficiency and discharge capacity decay rate, finding that electrochemical purification can enable cell performance equivalent to that with new and potentially-expensive materials. We anticipate this method of mitigating HER may reduce capacity maintenance needs and, in combination with other advances, further durational Fe-Cr RFBs.
Marketing Innovation and Management Reform Driven by Emerging Technologies
Authors: Ding Chunguang
Published: April 2022

The first part of this paper defines the concepts of marketing innovation and management reform, the four fulcrums of marketing innovation, as well as the necessity and modes of management reform. The second part summarizes the theoretical basis of this paper, and the third part analyzes the marketing environment of educational products under the background of the internet. Following that, the paper then discusses the problems existing in the marketing of education enterprise under the background of the new era, along with the countermeasures of enterprise marketing and management optimization. The last part of this paper is a summary of the content of the whole article.
Development of a Smart Cabinet Lock Based on Finger Vein Technology
Authors: Zhang Fan
Published: April 2022

In response to the requirements for the security and recognition accuracy of cabinet locks in communications, electric power, energy, chemical, IDC computer rooms, daily homes, and other occasions, a smart cabinet lock with multiple door-opening methods based on finger vein biometric technology is developed. The main method to unlock the cabinet is via finger vein unlocking; that is, the identification and verification of information by analyzing the pattern of the veins on the finger, and the achievement of identity verification and identification through biological detection. At the same time, it supports IC or ID card unlocking and mechanical manual unlocking. In order to simplify the overall structure, the internal mechanical structures of the aforementioned three unlocking methods are simplified into one. Its design focuses on the hybrid mechanical transmission structure and the finger vein module as well as utilizes the functions of each module. The principle is divided into blocks. Through processing and purchasing, the smart cabinet lock device is assembled, and its initial functional requirements are tested with physical objects. From the test results, it can be appreciated that the structural size, unlocking method, and two-way unlocking function of the smart cabinet lock meet the requirements, and its recognition accuracy is high, with good security and certain practical application prospects.
A Character Study of Little Linton in Wuthering Heights
Authors: Cao Yao
Published: April 2022

As the second-generation protagonist of Wuthering Heights, Little Linton’s appearance rekindled the conspiracy and love between two families. Under the guidance of his father, Heathcliff, he was forced to marry Cathy and eventually died tragically in Wuthering Heights. Looking at the whole classic, Little Linton played a crucial role in the development of the plot. By using relevant theories including “Gothic” character characteristics, repeated narration, and initiation stories, this paper analyzes Little Linton’s character, its forming factors, and his role in this work as well as explores the practical significance behind this character on the basis of an in-depth summary of his short life.
Commercial Credit and Corporate Performance: Business Credit or Business Trust
Authors: Li Yan , OuYang Xiaolin
Published: April 2022

With the development of capital market, commercial credit has gradually become an important part of market credit. Throughout the long-term development of the manufacturing industry, commercial credit has been one of the indispensable soft powers in the process of enterprise development. Therefore, enterprises should fully recognize and use commercial credit as a new means to improve enterprise performance. This paper selects the financial data of China’s listed manufacturing enterprises from 2010 to 2019, divides commercial credit into business credit and business trust, as well as studies the relationship between commercial credit and corporate performance. The empirical results show that the business credit of manufacturing enterprises has significant positive correlation with corporate performance, but there is no significant positive correlation between business trust and corporate performance. This paper also provides effective suggestions for manufacturing enterprises to enhance commercial credit.
Establishing a Mathematical Model for the Change of the Center of Gravity of Water Tanks
Authors: Cong Jing
Published: April 2022

The subject of center of gravity is inseparable from our daily lives; hence, the research on center of gravity has very important practical significance. This paper mainly studies the change of the center of gravity of a cuboid containing two water tanks upon flipping. Using the idea of differential equations, Visio and RealFlow are used to simulate the entire process, and the influence on the distance between the centroid and the center of gravity of the cuboid (including the water tanks) caused by the proportion of water in the water tank is studied and the inclination angle of the water tank is calculated via integration. By establishing a model through differential equations, the change of the center of gravity is studied when the cuboid (including the water tanks) is flipped.
Teaching Research of Material Mechanics Aimed at Stimulating Vocational College Students’ Interest Based on Simulation Technology
Authors: Wang Shang
Published: April 2022

Material Mechanics is an important course for science and engineering students in higher vocational colleges. However, its unfavorable teaching quality has been a problem for a long time. One of the key factors affecting the teaching effect is the students’ lack of interest in learning. In order to solve this problem, this paper analyzes the common problems in the teaching of Material Mechanics and applies simulation technology to classroom teaching. The results revealed that with the application of simulation technology, abstract concepts can be displayed visually and vividly, thus making it easier for students to understand. In addition, Mises stress nephograms and animations significantly improve students’ learning interest. The teaching method expounded in this paper should be applied to more courses in vocational education.
The Current Situation and Teaching Exploration of Engineering Mechanics in Vocational Colleges
Authors: Wang Shang
Published: April 2022

Engineering Mechanics is an important basic specialized course, which plays a connecting role in the teaching system. In recent decades, the reform of vocational education has been accelerating, leaving traditional teaching methods far behind. This paper systematically combs challenges existing in the teaching of Engineering Mechanics and puts forward targeted reform measures, among which the introduction of practical engineering cases, construction of online curriculum resources, application of digital visual materials, design of inquiry projects, and other new teaching methods should be given more attention by frontline teachers.
Deepening the Supply Side Structural Reform of Museums in China
Authors: Wang Nian
Published: April 2022

Deepening the supply side structural reform of museums in China refers to resolving the structural problems in the cultural supply of museums through reform, enhancing the adaptability of supply structure to demand, improving the cultural supply level and production efficiency, as well as balancing the relationship between supply and demand; it is the embodiment of China’s economic “new normal” in the development of museums. This paper discusses the necessity of the supply side reform of museums in China, the existing structural problems, and the concept as well as main contents of effective supply.
Analysis of Preventive Measures for Human Resource Management Risks
Authors: Li Jiapeng , An Pengyu
Published: April 2022

With the rapid development of China’s social economy, major enterprises are also developing rapidly. The development of the market economy presents a problem, whereby the market environment is becoming fiercely competitive. In order not to be eliminated in market competitions, it is necessary to secure the management of human resources. This is directly related to the key issue of whether enterprises are able to develop smoothly. However, there are still many problems in the current human resource management situation. One of the most important issues is the risk of human resource management, which has a huge impact on the development of enterprises. This paper begins by analyzing the source of risk in human resource management, and subsequently proposes some preventive measures based on the reasons. It is hoped that the proposal of these solutions can contribute to the socialist construction of the country.
Research on the Development of Music Information Retrieval and Fuzzy Search
Authors: Lee Kuo Ying , Hu Chih Ming
Published: April 2022

With the popularization of modern broadband networks, many network resources are serving as media for the public to seek knowledge. In order to help users avoid spending hours searching for music-related information, establishing an efficient multimedia database is the main goal of the music retrieval system. Network music retrieval users are usually unfamiliar with the songs and can only remember a portion of the music track, so it is important to develop a fuzzy algorithm in music search. In this research, the function and frame of various current music retrieval systems are discussed, a comparative analysis is carried out, and a new fuzzy search feedback learning algorithm is proposed as a potential application and the futuristic trend of music retrieval systems, so as to improve the retrieval efficiency.
微生物在含染料废水处理中的应用
Authors: 桂强 孙 , 胜发 刘
Published: April 2022

印染、染料废水是一种难以处理的工业废水。传统的物化处理工艺不仅成本高，而且会产生大量的淤渣，并且应用并不广泛。微生物技术由于克服了上述缺陷而日益引起人们的重视，目前已有许多有关微生物脱色性能的报道。研究表明，采用微生物技术对染料进行脱色、降解是一种经济、有效的方法。真菌、细菌、藻类等都能对某些染料进行降解，尤其是白腐菌对色素的去除作用更大。论文对近年来中国及其他国家对染料废水进行脱色处理的真菌、细菌、藻类等方面的研究结果进行了综述，并对其降解机制及一些影响因素进行了初步的探讨。
节能环保技术在污水处理中的应用
Authors: 育辰 刘 , 红 赵
Published: April 2022

随着中国城市化建设脚步逐渐加快，城市人口密度逐渐增大，相应的城市治理问题也日益凸显，其中的污水处理是城市建设管理中的重要环节，关系到城市卫生环境以及可持续发展，但是传统的污水处理方式并不能从根本上有效解决环境问题，随着人们对于绿色环保理念的认识逐步加深，亟需对污水处理机制进行创新与改革。论文针对污水处理对于生态环境的影响以及节能消耗问题进行分析，探索节能环保技术在污水处理中的应用。
基于 BIM 的建筑设计与应用研究
Authors: 峰旗 刘
Published: April 2022

BIM技术即建筑信息模型，它是一种数字化技术，能够在建筑工程的整个生命周期内为工程建设提供详细的数据信息。 BIM技术不仅可以降低工程项目成本，还能够缩短施工周期。因此，只有深入细致地分析BIM技术，才能够保证BIM技术在建筑工程设计中的运用效果。
钢管混凝土拱桥吊杆更换施工技术研究
Authors: 鹏 田
Published: April 2022

随着时代的不断发展，中国在拱桥技术方面有了一定的进步。钢管混凝土拱桥在现代化建设的今天应用在许多江河湖泊上。其中，吊杆具有十分重要的作用，是整个钢管混凝土拱桥的关键所在，但是在相关的技术方面还存在着一定的问题。基于此，论文从钢管混凝土拱桥的历史背景、吊杆的构造、吊杆的受损和钢管混凝土拱桥吊杆更换施工技术四个方面进行浅析。
市政给排水工程造价控制与管理的几点思考
Authors: 小东 唐
Published: April 2022

市政给排水工程作为城市化建设与发展的重要工作之一，其不仅对于城市建设与发展有着极其重要的影响，而且也与社会民众的日常生活、工作等有着密切的联系，所以市政给排水工程造价控制与管理得到了社会各界的广泛关注与重视。基于此，论文通过对市政给排水工程造价控制与管理的分析之后，提出了市政给排水工程造价控制与管理的几点建议，以期能为相关工作者提供工作参考建议。
Introducción a la Medicina Interna: conceptos actuales
Authors: Carrasco Ronquillo Gabriela Alexandra , Cueva Loaiza Adriana Malena , Campoverde Maldonado María José , Gualán Torres Thalía Fernanda , Arellano Salinas Karolina De La Paz , Giler Catagua Emiliano Orley , Moreno Vásquez Montserrat Janneth , Sinchiguano Navarro Paolo César , Rosero Caiza Javier Alejandro , Rosero Caiza Germán Esteban
Published: April 2022

La medicina interna es la especialidad médica que tiene el mayor número de consultas, pero muchos de los pacientes que consultan por primera vez a un especialista en medicina interna no tienen claro una definición precisa de la especialidad y de su función. La medicina interna es una de las especialidades de la medicina y se consagra al estudio, diagnóstico y tratamiento de las enfermedades del adulto; es de resaltar que los tratamientos que ofrece no son quirúrgicos, esta disciplina estudia al paciente de forma integral y ve al ser humano de forma holística, es decir, ve todos los sistemas y el funcionamiento de cada órgano con el objetivo de preservar la salud de los pacientes. La consulta de Medicina Interna es de gran trascendencia en las especialidades médicas, es el lugar idóneo para diagnosticar y establecer la estrategia terapéutica de los pacientes, busca en lo posible, resolver el problema de salud de un paciente en el mismo día de la consulta, coordinando las pruebas complementarias para tal fin. Los internistas se forman bajo el principio de que ninguna enfermedad o problema clínico del adulto es ajeno a su incumbencia y responsabilidad, esta actitud ha llevado a participar activamente en la mayoría de los retos asistenciales a los que ha tenido que hacer frente.
ОПТИМІЗАЦІЙНА МОДЕЛЬ ЕЛЕКТРОПОТЯГА З ЕЛЕКТРОПРИВОДОМ ПОСТІЙНОГО СТРУМУ
Authors: Zapolovsky M. , Zykov I. , Mezentsev M. , Noskov V.
Published: April 2022

Розглянуті питання розроблення оптимізаційної математичної моделі електропотяга з електроприво дом постійного струму з послідовним збудженням та її реалізації в пакеті МАТLAB з метою побудови системи керування на основі методу принципу максимуму. Проведено огляд літературних джерел на задану тематику та аналіз існуючих підходів до розв’язання задач моделювання складних електромеханічних систем та синтезу систем керування у даній галузі, зокрема систем керування, які забезпечують мінімізацію енергетичних затрат. Побудовані математичні моделі досліджуваних об’єктів керування, проведене моделювання їхнього функціонування в залежності від рівня завантаженності. Отримані аналітичні співвідношення, які можуть бути використані для розробки структури САК електроприводу електропотягу і розрахунку його параметрів при заданому критерію якості. Проведені дослідження оптимізаційної моделі підтверджують її працездатність та її ефективність для розробки систем керування при заданому критерії якості іступені завантаженості.
АВТОМАТИЗОВАНА СИСТЕМА ДЛЯ МОДЕЛЮВАННЯ ТЕРМІЧНИХ ОПІКІВ ШКІРИ У ЕКСПЕРИМЕНТАЛЬНИХ ТВАРИН
Authors: Yankovsky O. , Yankovska D. , Polikarpova H.
Published: April 2022

У статті розглянута автоматична система для моделювання термічних опіків шкіри у експериментальних тварин. Запропонована система складається з нагрівального елементу з підключеним до нього датчиком температури, комп'ютеру (або ноутбук), до якого через інтерфейс USB підключається зовнішній виконавчий пристрій, реалізований на мікроконтролері, який регулює температуру нагрівального елемента за допомогою широтноімпульсної модуляції. Програмне забезпечення дозволяє задавати необхідні параметри термічного впливу (температуру, час, кратність) та передбачає можливість його розширення використанням автоматичного підбору температури та часу впливу в залежності від виду експериментальної тварини, ділянки тіла, що підлягає впливу та бажаного ступеня опіку. Наявність комп’ютера дає змогу вносити та зберігати дані щодо умов експерименту, тварин та результати досліджень з автоматичним формування карток експериментальних тварин та можливістю переносити дані до інших програм, наприклад для статистичної обробки результатів. Система може бути застосована для досліджень в області біології та медицини, зокрема у доклінічних випробуваннях препаратів.
Meta-analysis of the Effect of Excess Waist Circumference on Hypertension Incidence in Adolescents
Authors: Zuhaira Ulul Azmi , Irwan Viola Fathia
Published: April 2022

Background: Hypertension is a condition characterized by blood pressure measurements showing a systolic pressure of >130 mmHg and a diastolic pressure of >80 mmHg. There are so many cases of hypertension in adolescents that begin with being overweight or obese. One way to determine a person's level of obesity is by measuring the waist-to-hip ratio. This study was aimed to analyze the effect of excess waist circumference on the incidence of hypertension in adolescents.
Subjects and Method: This study is a meta-analysis study with the following PICO, population: adolescents. Intervention: excess waist circumference. Comparison: normal waist circumference. Outcome: hypertension. This study uses PRISMA flowchart guidelines. The article search process was carried out between 2011-2021 using online databases, namely PubMed, Google Scholar, and Science Direct. Based on the database, there were 9 articles that met the inclusion criteria. The analysis was carried out using RevMan 5.3 software.
Results: There are 9 cross-sectional studies originating from 2 continents, namely America and Asia. Based on the data showed that adolescents with excess waist circumference increased the risk of hypertension 1.59 times compared to adolescents with normal waist circumference (aOR= 1.59; 95% CI= 1.00 to 2.52; p= 0.050).
Conclusion: Excess waist circumference increases the risk of hypertension in adolescents.
Keywords: hypertension, waist circumference, teens
Correspondence: Ulul Azmi Zuhaira. Politeknik Kesehatan Kemenkes Malang. Jl. Besar Ijen No. 77 C, Oro-oro Dowo, Kec. Klojen, Kota Malang, Jawa Timur. Email: ululazmizuhaira@gmail.com. Mobile: +62822-4501-2258.
Risk Factors for Anxiety in Housewives during the COVID-19 Pandemic
Authors: Khasana Sifa Latif , Wibowo Yudhi , Wulansari Rahmawati
Published: April 2022

Background: The COVID-19 pandemic has a psychological impact on society, namely anxiety. Factors that influence anxiety during the COVID-19 pandemic are age, education level, occupation, and history of being diagnosed with COVID-19. This study aims to determine the risk factors for anxiety in housewives during the COVID-19 pandemic.Subjects dan Method: An observational analytic study with a cross-sectional approach was conducted in South Purwokerto, Central Java. The sample is 70 housewives selected by simple random sampling. The dependent variable is anxiety. independent variables were age, education, occupation, and COVID-19 infection. Anxiety was measured by the Hamilton Rating Scale for Anxiety (HRS-A) questionnaire. Other variables were collected by questionnaire. Data were analyzed using Chi-square.Results: Age 40 years (OR= 1.55; 95%CI= 0.76 to 3.14; p= 0.330), higher education level (OR= 1.96; 95%CI= 1.03 to 3.71; p= 0.070), informal occupation (OR= 1.24; 95%CI= 0.44 to 3.48; p= 1,000), and a history of COVID-19 infection (OR= 31.10; 95%CI= 4.44 to 217.91; p<0.001) increased anxiety among housewives.Conclusion: Age 40 years, higher education level, informal occupation, and history of COVID-19 infection increase anxiety among housewives during the COVID-19 pandemic.
Keywords: COVID-19, housewife, anxiety
Correspondence:Sifa Latif Khasana. Faculty of Medicine, Universitas Jenderal Soedirman. Jl. Dr. Gumbreg 1, Mersi, Purwokerto Kidul, Purwokerto 53147, Banyumas, Central Java. Email: sifalatifkhasana@gmail.com. Mobile: 085826669720.
The Effect of Maternal Anemia on Low Birth Weight: Meta Analysis
Authors: Tursina Elsa , Adhimukti Fahmi
Published: April 2022

Background: Low birth weight is still a global public health problem that is associated with a number of risks. One of the factors that influence the occurrence of LBW is anemia. This study was aimed to estimate the risk of anemia in pregnant women to the incidence of LBW in several countries.Subjects and Method: This study is a meta-analysis with PICO, Population: pregnant women. Intervention: maternal anemia. Comparison: no maternal anemia. Result: LBW. The articles used in this study were obtained from three databases namely Google Scholar, Pubmed, and Science Direct with a cohort study design from 2015 to 2022 that reported Adjusted Odds Odds Ratio in its multivariate analysis. The selection of articles was carried out using the PRISMA flow chart. Analysis of articles using the Review Manager 5.3 application.Results: A total of 9 cohort studies involving 75,807 pregnant women from Taiwan, China, Japan, India, Bangladesh, Iran, and Colombia were selected for systematic review and meta-analysis. The data collected showed that pregnant women who were anemic during pregnancy had a 1.3 times higher risk of giving birth to babies with low birth weight than non-anemic mothers, but this result was not statistically significant (aOR= 1.30; 95% CI= 0.89 to 1.88; p= 0.170). With an intuitive index of 84%, so the effect between the studies is heterogeneous.Conclusion: Mothers who experience anemia during pregnancy have a risk of giving birth to babies with low birth weight.
Keywords: anemia, pregnancy, low birth weight
Correspondence:Fahmi Adhimukti. Study Program of Midwifery, Diploma IV, Health Polytechnics, Ministry of Health Surakarta. Jl. Tata Bumi 3, Sleman, Yogyakarta, Indonesia. Email: fahmiadhimukti13@gmail.com. Mobile: 085743155133.
Smart nanofibres for specific and ultrasensitive nanobiosensors and drug delivery systems
Authors: Pashchenko Aleksei , Stuchlíková Simona , Varvařovská Leontýna , Firment Peter , Staňková Laura , Nečasová Andrea , Filipejová Zita , Urbanová Lucie , Jarošíková Taťána , Nečas Alois , Amler Evžen
Published: April 2022

Biosensors are dynamically developing analytical devices for the detection of substrates or other bioactive substances. They can be used for quick gas or liquid analyses and the construction of sensitive detection systems. This review highlights the advances and development of biosensors suitable for human and veterinary medicine and, namely, a novel contribution of nanotechnology for ultrasensitive diagnosis and personalized medicine. The synergic effect of nanotechnology and biosensors opens a new dimension for effective treatment and disease detection at their early stages.
The impact of SARS-CoV-2 on respiratory syndromic and sentinel surveillance in Israel, 2020: a new perspective on established systems
Authors: Glatman-Freedman Aharona , Gur-Arie Lea , Sefty Hanna , Kaufman Zalman , Bromberg Michal , Dichtiar Rita , Rosenberg Alina , Pando Rakefet , Nemet Ital , Kliker2, Limor , Mendelson Ella , Keinan-Boker Lital , Zuckerman Neta S , Mandelboim Michal ,   on behalf of The Israeli Respiratory Viruses Surveillance Network (IRVSN)
Published: April 2022

Background

The COVID-19 pandemic presented new challenges for the existing respiratory surveillance systems, and adaptations were implemented. Systematic assessment of the syndromic and sentinel surveillance platforms during the pandemic is essential for understanding the value of each platform in the context of an emerging pathogen with rapid global spread.

Aim

We aimed to evaluate systematically the performance of various respiratory syndromic surveillance platforms and the sentinel surveillance system in Israel from 1 January to 31 December 2020.

Methods

We compared the 2020 syndromic surveillance trends to those of the previous 3 years, using Poisson regression adjusted for overdispersion. To assess the performance of the sentinel clinic system as compared with the national SARS-CoV-2 repository, a cubic spline with 7 knots and 95% confidence intervals were applied to the sentinel network's weekly percentage of positive SARS-CoV-2 cases.

Results

Syndromic surveillance trends changed substantially during 2020, with a statistically significant reduction in the rates of visits to physicians and emergency departments to below previous years' levels. Morbidity patterns of the syndromic surveillance platforms were inconsistent with the progress of the pandemic, while the sentinel surveillance platform was found to reflect the national circulation of SARS-CoV-2 in the population.

Conclusion

Our findings reveal the robustness of the sentinel clinics platform for the surveillance of the main respiratory viruses during the pandemic and possibly beyond. The robustness of the sentinel clinics platform during 2020 supports its use in locations with insufficient resources for widespread testing of respiratory viruses.
Seasonality of respiratory syncytial virus and its association with meteorological factors in 13 European countries, week 40 2010 to week 39 2019
Authors: Li You , Wang Xin , Broberg Eeva K , Campbell Harry , Nair Harish ,   European RSV Surveillance Network
Published: April 2022

Background

Respiratory syncytial virus (RSV) is the predominant cause of clinical pneumonia among infants and young children, often peaking during the winter months in temperate regions.

Aim

To describe RSV seasonality in 13 European countries and examine its association with meteorological factors.

Methods

We included weekly RSV seasonality data from 13 European countries between week 40 2010 and week 39 2019. Using local weighted regression method, we modelled weekly RSV activity with meteorological factors using data from the 2010/11 to the 2017/18 season. We predicted the weekly RSV activity of the 2018/19 season across 41 European countries and validated our prediction using empirical data.

Results

All countries had annual wintertime RSV seasons with a longitudinal gradient in RSV onset (Pearson’s correlation coefficient, r = 0.71, 95% CI: 0.60 to 0.80). The RSV season started 3.8 weeks later (95% CI: −0.5 to 8.0) in countries in the eastern vs western parts of Europe, and the duration ranged from 8–18 weeks across seasons and countries. Lower temperature and higher relative humidity were associated with higher RSV activity, with a 14-day lag time. Through external validation, the prediction error in RSV season onset was −2.4 ± 3.2 weeks. Similar longitudinal gradients in RSV onset were predicted by our model for the 2018/19 season (r = 0.45, 95% CI: 0.16 to 0.66).

Conclusion

Meteorological factors, such as temperature and relative humidity, could be used for early warning of RSV season onset. Our findings may inform healthcare services planning and optimisation of RSV immunisation strategies in Europe.
Two fatal autochthonous cases of airport malaria, Belgium, 2020
Authors: Van Bortel Wim , Van den Poel Bea , Hermans Greet , Vanden Driessche Marleen , Molzahn Helmut , Deblauwe Isra , De Wolf Katrien , Schneider Anna , Van Hul Nick , Müller Ruth , Wilmaerts Leen , Gombeer Sophie , Smitz Nathalie , Kattenberg Johanna Helena , Monsieurs Pieter , Rosanas-Urgell Anna , Van Esbroeck Marjan , Bottieau Emmanuel , Maniewski-Kelner Ula , Rebolledo Javiera
Published: April 2022

We report an outbreak investigation of two fatal cases of autochthonous Plasmodium falciparum malaria that occurred in Belgium in September 2020. Various hypotheses of the potential source of infection were investigated. The most likely route of transmission was through an infectious exotic Anopheles mosquito that was imported via the international airport of Brussels or the military airport Melsbroek and infected the cases who lived at 5 km from the airports. Based on genomic analysis of the parasites collected from the two cases, the most likely origin of the Plasmodium was Gabon or Cameroon. Further, the parasites collected from the two Belgian patients were identical by descent, which supports the assumption that the two infections originated from the bite of the same mosquito, during interrupted feeding. Although airport malaria remains a rare event, it has significant implications, particularly for the patient, as delayed or missed diagnosis of the cause of illness often results in complications and mortality. Therefore, to prevent such severe or fatal outcomes, we suggest a number of public health actions including increased awareness among health practitioners, especially those working in the vicinity of airports, and increased surveillance of exotic mosquito species at airports.
“THEY MADE AN ELEPHANT OUT OF A FLY”. S.I. MURAV’EV-APOSTOL AND THE UNREST IN THE SEMYONOVSKY REGIMENT IN 1820
Authors:   Russian State University for the Humanities, Kiyanskaya Oksana I. ,   Institute of Scientific Information for Social Sciences of the Russian Academy of Sciences
Published: April 2022

The article deals with the soldiers’ unrest in the Semyonovsky Regiment in 1820, which, according to many researchers, was a kind of “prelude” to the Decembrist uprising. After the soldiers’ unrest in October 1820, the Semyonovsky Guards Regiment was disbanded and its officers were transferred to the army regiments. The article explores the causes of soldiers’ and officers’ dissatisfaction with the regiment’s commander, Colonel F.E. Schwartz, the course of the riots in the regiment, and the behavior of the officers. In addition, the article investigates the case of Semyonovsky Regiment officers, D. Yermolaev and I. Scherbatov, accused of sympathizing with the soldiers and attempting to meet with the punished instigators of riots. The Semyonov history is considered in connection with the biography of one of its participants, the future Decembrist S.I. Murav’ev-Apostol. The article describes the events in the company commanded by Muravyov-Apostol, as well as the consequences that this “story” had for his life and career. It is concluded that by offending an innocent officer, the authorities thereby contributed to his transformation into a radical revolutionary and leader of an antigovernment conspiracy
“POST-COLONIAL DISCOURSE”. THE GLOBAL CONTEXTS
Authors:   Primakov National Research Institute of World Economy and International Relations, Rashkovsky Eugene B. ,   Russian Academy of Sciences
Published: April 2022

This article presents some theoretical as well as historiographical reflections concerning new Russian monograph “Africa: Post-Colonial Discourse” (Moscow, 2020). The aim of this study is to comprehend some problems of the basic contemporary macro-historical studies, as following: expanding the competence of the present-day source-based global studies; more comprehensive understanding of macro-historical phenomenon of slavery and – wider – of compulsive labor as one of the most tragic and unjust universals of global history; and perceiving of the imprescriptible role of inter-cultural as well as inter-civilizational codevelopment in possible humanization of global reality. Post-colonial discourse hardly seems to be an exact solution of all the controversial problems of the XV–XXI centuries’, so deep and so painful. Nevertheless, it poses some basic questions of the History as such including questions of compulsion and violence in history as well as the question of hope for freedom and dignity as an ultima ratio of all the human cultural experience.
WESTERN EUROPEAN MIDDLE AGES AND “MAGIC” SPACE IN SOUTH KOREAN TELEVISION SERIES: “MEMORIES OF THE ALHAMBRA” AND OTHERS
Authors:   Russian State University for the Humanities, Tarasova Aleksandra V.
Published: April 2022

The use of the “image of the Middle Ages” in popular works of art and its impact on the perception of the past by a wide audience has traditionally been defined as “medievalism”. The study of “medievalism” has become a special area in the humanities. However, since the Middle Ages is a concept associated with the periodization of the history of Western Europe, the concept of “medievalism” often includes products created in the conditional West and fictional worlds constructed from elements perceived as “Western”. More importantly, such products are usually aimed at a “Western” audience – that is, at viewers who perceive the European Middle Ages as part of their own culture (even if in fact the product is intended for a global audience). The article attempts to analyze the image of the Middle Ages in popular TV series in South Korea: their main viewer is an internal viewer, for whom the history of the Middle Ages is something extremely distant both from the history of his own country and from him/her personally. An analysis of several TV series that use “medieval” images shows that the medieval heritage of the West is perceived as a very attractive background for a part of the plot, but the “historical” in these narrations reveals the ability to easily transform into the “magical”.
Propiedades psicométricas de la escala de depresión geriátrica: revisión sistemática
Authors: Molina-Calle Carmen Victoria , Ramírez-Coronel Andrés Alexis , Mesa-Cano Isabel Cristina , Alvarado Maldonado Hugo Patricio , Martínez-Suárez Pedro Carlos
Published: April 2022

Depression is the most common mental disorder among older adults and one of the most disabling conditions worldwide.  General objective: To review the scientific evidence on the psychometric properties of the geriatric depression scale. Methodology: A documentary study of systematic literature review was carried out. Regarding the search strategies, we worked with the library of the Catholic University of Cuenca, the Scopus, Pubmed and Web of Science databases were used, from 2017 to 2021in English and Spanish language.  This allowed obtaining a total of 14 articles that were thoroughly analyzed. Main results: The Geriatric Depression Scale (GDS) has adequate, reliable, and valid psychometric properties to assess knowledge about geriatric depression, thus contributing for students, health profession, because it is a brief and easy to apply screening instrument, widely used in clinical and research to detect depressive symptoms in older adults that can provide a reliability of an adequate diagnosis. Conclusion: It is concluded that the GDS is a reliable instrument to apply in the older adult population.
Influencia de la curvatura en la formación de patrones: el mecanismo de Turing en el círculo
Authors: Núñez-López Mayra , Chacón-Acosta Guillermo
Published: April 2022

En este trabajo estudiamos la influencia de la curvatura del medio sobre la formaci´on de patrones mediante el mecanismo de inestabilidad de Turing generada por difusi´on. Para analizar el efecto de la curvatura consideramos la variedad curva cerrada m´as simple, una circunferencia. Presentamos el operador de Laplace-Beltrami, que es la generalizaci´on del Laplaciano sobre variedades, con el fin de resolver la ecuaci´on de difusi´on y describir las modificaciones que induce la curvatura en la funci´on de distribuci´on y en el camino cuadr´atico medio. Como un caso particular de estudio empleamos el modelo de Gierer-Meinhardt. Se muestra que el rango de modos inestables donde ser´a posible hallar los patrones espacio-temporales depende del radio y, por lo tanto, de la curvatura del c´ırculo espec´ıfico.
Una formulación de orden fraccionario de un modelo simplificado de la dinámica de citoquinas
Authors: González-Ramírez Laura Rocío
Published: April 2022

En este trabajo, se presenta un modelo matemático de orden fraccionario de la din´amica de la interacción entre dos grupos de citoquinas. Se considera un ejemplo de aplicaci´on de una droga que modifica la interacción inhibitoria entre estos dos grupos. Esta formulaci´on sencilla puede modelar el complejo proceso que se lleva a cabo durante la llamada tormenta de citoquinas, mediante el cual un desbalance en la producci´on de citoquinas puede producir una hiperexcitaci´on de las mismas. En el modelo de orden entero, se establecen resultados cualitativos de una transici´on de un estado de baja concentraci´on a un estado de alta concentraci´on de citoquinas conforme la dosis de droga aumenta. Con la formulaci´on de orden fraccionario obtenemos resultados cualitativos que indican que el sistema se resiste a esta transici´on, permaneciendo por más tiempo en estado de baja concentraci´on. De acuerdo a la interpretaci´on de derivada fraccionaria como índice de memoria, al aumentar el ´ındice de memoria del sistema este es más resistente a la aplicaci´on de la droga, y esto produce que se necesite una dosis más fuerte para la transici´on de un estado bajo de concentraciónn de citoquinas a un estado hiperexcitado.
Flujo Global del Problema Colineal de Kepler con perturbación de Mundos Brana
Authors: Criollo-P´erez Arturo , Pedraza-Ortega Omar
Published: April 2022

En este trabajo analizamos el problema colineal de Kepler bajo la influencia de una perturbación proveniente de Mundos Brana $(\lambda \cos x)/x $, para $\lambda\in \mathbb{R}^+$. En la primera parte, hacemos un análisis detallado del potencial perturbativo, posteriormente, se construyen los retratos fase para distintos valores del parámetro de perturbación $\lambda$. Empleando la técnica de la explosión, se regularizan las singularidades debidas a colisión y los escapes a infinito. Finalmente, se lleva a cabo una caracterización global del flujo.