bluuebunny/crossref_metadata_2025 huggingface dataset:
Oral Health Misinformation on Youtube – A Content Analysis
Authors: Riyaz Mohammed Meera , Gousalya V , Anu V , Prashanth S , Ram S Prabhu , Varshini VJ Keerthi , Rajsanjay R
Published: January 2025

ABSTRACT

Introduction:

With the rise of social media and widespread smartphone use, information is now readily accessible worldwide. However, the credibility of this information often remains unchecked. Few studies have evaluated oral health content on online platforms. However, YouTube, despite its popularity, is frequently overlooked. This study aims to identify and analyze oral health misinformation on YouTube.

Methods:

A search was done on YouTube using common keywords related to oral health through Google chrome browser with incognito mode to limit the bias associated with Google accounts. The videos obtained were subjected to analysis using a coding framework and both auditory and visual content were examined together by two coders to ensure a comprehensive coding process. All the videos were classified either as accurate information (useful) or misleading information.

Results:

A total of 72 videos were included in the study, of which about 55% of them had misleading content. About 75% of the videos containing misleading information were created by non-professionals and only about 15% of the videos containing misleading information were created by medical professionals. It was surprising to note that the misleading information had more positive engagement metric (137429) than the useful information (71207).

Conclusion:

From the content analysis, it was found that there was a large amount of misleading information on oral health in YouTube. Therefore, it’s crucial to address the potential risks of misleading content and to increase public awareness about the impact of following such misleading information.
In Silico toxicity assessment of Euphorbia hirta
Authors: Subramani Prabhu , Murugappan Senthil , Ganeshi Gajalakshm , Jones Sumathi , Mani Devi
Published: January 2025

ABSTRACT

Background:

Herbs have evolved as an alternative and safer option in deriving antibiotics to combat antimicrobial resistance. Euphorbia hirta is a tropical weed. It possesses many beneficial medicinal values; the present study was undertaken to determine in silico toxicity of Eurphorbia hirta.

Materials and Methods:

In silico toxicity estimation was carried out using The Toxicity Estimation Software Tool (TEST). LC50 threshold was calculated using TEST software based on predictions from each model and the consensus average of the component models.

Results:

The phytoconstituents 3, 7, 11, 15-tetramethyl-2-hexadecen-1-ol, 9, 12, 15-octadecatrienoic acid, 9-octadecenamide, henicosane, hentriacontane, hexadecanoic acid, hexadecanoic acid, methyl ester, phytol, squalene, tetracosane, and Urs - 12- 2n-24-oic acid, 3-oxo-, methyl ester are nontoxic.

Conclusion:

Phytochemical constituents of Euphorbia hirta exhibit an acceptable toxicity limit for drug production and preclinical and clinical appraisal.
Fatigue Syndrome among Medical Students in Saudi Arabia: A Cross-Sectional Study on Depression and Anxiety
Authors: Alkhamees Abdulmajeed A. , Algubllan Lamees Abdulaziz , Alsughier Naif , Alwashmi Ahmad H. , Alamr Deem Tariq , Alharbi Aeshah Menawer , Alturaif Norah Abdullah
Published: January 2025

ABSTRACT

Objective:

This cross-sectional investigation aimed to determine fatigue syndrome (FS) prevalence and its association with depression and anxiety among medical students in Saudi Arabia.

Materials and Methods:

An online survey was performed using a pretested questionnaire comprising four sections: sociodemographic information, the 11-item Chalder Fatigue Questionnaire (CFQ), the 9-item Patient Health Questionnaire (PHQ-9), and the Generalized Anxiety Disorder 7-item (GAD-7) scale. A total of 740 medical students participated in the cross-sectional study.

Results:

The study found that 56.4% of the students met the diagnostic criteria for FS, with female students (69.7%) showing higher FS prevalence compared to male students (30.3%). FS was significantly associated with symptoms of depression (r = 0.68, P < 0.001) and anxiety (r = 0.54, P < 0.001). Other factors associated with higher FS scores included higher body mass index, lack of physical activity, and a history of substance use.

Conclusion:

FS is highly prevalent among medical students in Saudi Arabia, particularly among females. The association between FS and mental health symptoms underscores the need for targeted interventions to manage FS and its psychological impact in this population.
Clinical Outcomes and Stroke Recurrence in Moyamoya Disease Post-Revascularization: A Retrospective Analysis
Authors: Alhumaid Alanoud , Taher Nouran , Alanazi Rahmah , Bensaeed Nora Z.
Published: January 2025

ABSTRACT

Objectives:

This study aimed to assess the clinical characteristics, treatment outcomes, and recurrence risks in moyamoya disease (MMD) patients, focusing on the impact of revascularization and antiplatelet therapy.

Materials and Methods:

Forty-six MMD patients were analyzed. Data on demographics, clinical characteristics, treatment outcomes, and recurrence rates of ischemic and hemorrhagic strokes were collected. The effectiveness of revascularization and the role of antiplatelet therapy in preventing recurrent strokes were statistically evaluated.

Results:

The mean age was 19.5 years. Right-side weakness (28.3%) and left-side weakness (21.7%) were common symptoms. Pre-revascularization, recurrent ischemic strokes affected 58.7% of patients; post-revascularization, the incidence dropped to 8.7%. However, a high recurrence rate (39.1%) persisted among those not undergoing surgery. Post-revascularization hemorrhagic strokes were rare (6.5%). Antiplatelet therapy significantly reduced ischemic stroke recurrence (P < 0.001) and hemorrhagic stroke risk.

Conclusion:

Early intervention and continuous antiplatelet therapy are crucial in managing MMD. Despite reduced ischemic stroke recurrence post-revascularization, functional outcomes often remained unimproved, indicating the need for optimized treatment strategies.
Comparative Analysis of Fluoride Removal Efficacy of Drinking Water with Moringa Oleifera Seeds, Leaves and its Barks as Economic and Cost-Effective Bioadsorbents
Authors: Manikandan Saranya , Ramesh Maya , Yoithapprabhunath Thuckanaickenpalayam R. , Kalidhas Priya , Sundaram Manikandan , Krishnan Ramesh
Published: January 2025

ABSTRACT

Background:

Fluorides are the most important pollutants present in the effluents from various industrial and groundwater sources. These are very poisonous to living beings and have a dangerous effect on their health. Fluoride in drinking water within permissible limits of 0.5-1.0 mg/L is useful for the production and of maintenance healthy, teeth and bones as extreme intake of fluoride causes dental and skeletal fluorosis. Thus the removal of fluoride using adsorbents is a main step towards the protection of environment.

Methods:

The water samples are collected from wells of Salem district. Previous to sampling, the water is left to run from the source for few minutes. The study for presence of fluoride in groundwater samples is carried out as per APHA standard methods. Fluoride concentration be determined with SPADNS method spectrometric ally by use zirconyl-SPADNS (sodium 2-(parasulphophenylazo)-1, 8-dihydroxy-3, 6-naphthalene-disulphonate) reagents.

Results:

The significant difference in average score is tested through the analysis of variance after testing the normality test and it shows there is highly significant difference is found in the Fluoride Removal with respect to Moringaoleifera seeds, Moringaoleifera leaves, Moringaoleifera barks since the p value is less than 0.01.

Conclusion:

Drinking water is an essential basic need. The use of adsorbents is simple, cheap, non-toxic and environmentally friendly, its adoption for the defluoridation of drinking water. Based on the results of this study, it can be concluded that the low-cost adsorbents are effective in removal of fluoride from water.
Smoking Behaviors and Health Risk Awareness Among Healthcare Students in Alkharj, Saudi Arabia
Authors: Almalki Sultan A. , Gowdar Inderjit M. , Alanazi Bashar A. , Alqahtani Osama A. , Alanazi Fahad R. , Al-Harbi Khalid F.
Published: January 2025

ABSTRACT

Objective:

This study examines smoking behaviors, including the age of initiation, daily consumption, cessation attempts, and awareness of smoking-related health risks among male healthcare professional students in Alkharj, Saudi Arabia.

Methods:

A cross-sectional survey was conducted with 308 male students across four healthcare disciplines: Medicine, Dentistry, Nursing, and Pharmacy. A structured questionnaire collected data on smoking status, initiation age, daily cigarette consumption, reasons for smoking, cessation attempts, and awareness of systemic and oral diseases caused by smoking. Descriptive statistics and Chi-Square tests were used to identify significant differences among disciplines.

Results:

The prevalence of smoking varied significantly among the different disciplines, with Pharmacy students having the lowest smoking rate (16.2%) and Dental students the highest (38.5%) (P = 0.005). Most smokers began smoking between the ages of 18-21. The majority of smokers consumed 3-5 cigarettes per day. Awareness of smoking-related systemic diseases, such as lung cancer, was high across all groups, though knowledge of smoking-related oral diseases varied. Attempts to quit smoking were most prevalent among Dental students (66.7%), indicating a significant difference in cessation efforts across disciplines (P = 0.04).

Conclusion:

The study highlights significant differences in smoking behaviors and awareness across healthcare disciplines. These findings underscore the critical need for targeted educational interventions to address smoking behaviors and improve health literacy among healthcare professional students. By focusing on discipline-specific approaches, it is possible to enhance the effectiveness of tobacco control programs and promote healthier lifestyles among future healthcare providers.
Computational Studies on Recent Congeners of Fluoroquinolones and Nitroimidazoles for Their Use in Periodontal Therapy
Authors: Natarajan Prabhu Manickam
Published: January 2025

ABSTRACT

Background:

Periodontitis is a slow progressing infection and has profound systemic implications. The influence of various therapeutic drugs to inhibit inflammation and promote bone regeneration has been studied. Introduction of newer congeners of older drugs necessitates testing the efficacy of newer drugs for the said use.

Aim:

The aim was to determine the effectiveness of newer nitroimidazoles and fluoroquinolones for controlling and eliminating periodontal pathology by binding to the targets.

Methods and Material:

A total of 12 drugs were selected, and the chemical structure drugs used were retrieved form PubChem and development of 2d and 3d structures was done using chem draw software. Targets used were Gingipain K, FimA, Interleukin-1β, and Estrogen Receptor β. AutoDock version 4 software was used for in silico docking simulations. The binding free energy, inhibition constant, electrostatic energy, intermolecular energy, and total interaction surface are all provided by the docking tool. In this paper, the optimal docking pose for each target is chosen and presented.

Results:

From the results of the study, it can be observed that gatifloxacin and ciprofloxacin have more affinity and interactions with all four targets were analyzed.

Conclusions:

This study has effectively tested nitroimidazoles and fluoroquinolones comparatively and proposed that fluoroquinolones are more effective for blocking periodontitis.
Decoding Mandibular Angle Fracture Management: Biomechanical Analysis of Different Plating Techniques – An In Vitro Study
Authors: Subramanian Adalarasan , Sambanthan Thiruneelakandan , Punithan Akash , Petchiammal S Meera , Laxmi R. Bhuvana , Srikanth Vishal , Eswar E
Published: January 2025

ABSTRACT

Objective:

The primary rationale of the study is to assess the biomechanical aspects of Champy’s, monoplanar, biplanar, and 3D strut plating systems using an in vitro model in the management of the angle of mandible fracture.

Methods:

Thirty-two hemi-sectioned mandibles (N = 32) were obtained from adult goats and divided into four groups (N = 8) for different plating techniques: monoplanar, biplanar, Champy’s, and three-dimensional curved angle strut plating. A customized biomechanical test machine simulated masticatory loads by applying compressive forces. Force versus displacement data were recorded using an Instron Lloyd LRX machine.

Results:

Plating techniques with two plates exhibited higher resistance to displacement than single-plate techniques. The three-dimensional curved angle strut plate group had the highest mean compressive strength (184.7913 N), followed by biplanar plating (170.29 N), monoplanar plating (159.3419 N), and Champy’s plating (55.48375 N). Statistical analysis showed significant differences between the three-dimensional curved angle strut plating technique and Champy’s plating technique (P value ≤ 0.0016*), as well as between the biplanar plating technique and Champy’s plating technique (P value ≤ 0.0010*).

Conclusion:

The three-dimensional curved angle strut plate and biplanar plating techniques exhibited superior biomechanical performance compared to monoplanar and Champy’s plating techniques.
Low-Grade Chondroid Variant Osteosarcoma: A Rare Case Report and Diagnostic Insights
Authors: Anitha N , Dhivyadharshini S , Babu N Aravindha , Masthan K M K
Published: January 2025

ABSTRACT

Osteosarcoma is a rare malignant tumor that primarily affects the jaw bones, with the low-grade chondroid variant being an uncommon subtype that often mimics benign lesions. This case report details the clinical presentation, histopathological findings, radiographic evidence, and treatment approach for a 23-year-old male who presented with recurrent gingival growth and pain in the lower anterior region. Initially misdiagnosed as a pyogenic granuloma, further evaluation revealed the presence of low-grade chondroid variant osteosarcoma. This case underscores the necessity for a thorough investigation of recurrent oral lesions and the importance of timely biopsy and accurate histopathological interpretation for effective management. The unique radiographic and histopathological features of this variant are discussed, emphasizing the critical need for differential diagnosis in similar clinical scenarios.
The Crucial Role of Smoking Cessation in Preventing Oral Cancer
Authors: Natarajan Prabhu Manickam , Swamikannu Bhuminathan , Rahe Rajan , Kamaraj Bindu , Kamaraj Loganathan , Ramachandran Veerakumar
Published: January 2025

ABSTRACT

Oral cancer remains a significant public health concern globally, with smoking being a primary risk factor. Smoking cessation has been identified as a crucial intervention in reducing the incidence of oral cancer. This abstract reviews the impact of smoking cessation on oral cancer prevention, emphasizing the benefits of quitting smoking in decreasing the risk of developing oral malignancies. Evidence suggests that smoking cessation not only reduces the immediate risk of oral cancer but also contributes to long-term health improvements. The mechanisms through which smoking cessation exerts its protective effects, including the reduction of carcinogenic exposure and enhancement of oral mucosal health, are discussed. Public health strategies and interventions aimed at promoting smoking cessation are also highlighted as essential components in oral cancer prevention efforts.
A Review of Contributing Factors to Heart Failure: Genetic, Lifestyle, and Environmental Influences
Authors: Thotakura Balaji , Vidya S , Sheena K. S , Roy D Dinesh , Prabhu K , Jones Sumathi
Published: January 2025

ABSTRACT

Background:

: Heart failure (HF) is a multifaceted syndrome influenced by genetic, environmental, lifestyle, and comorbid factors. Understanding these diverse aspects is crucial for effective management and treatment. This systematic review aims to synthesize current evidence on the multifactorial aspects of HF, providing insights for comprehensive care strategies.

Methods:

This review involved a thorough literature search across databases such as PubMed, MEDLINE, and EMBASE, focusing on studies published up to January 2024. It included research examining the role of genetic predispositions, lifestyle factors, and comorbid conditions in HF. Studies were evaluated for quality by using standardized assessment tools, and a meta-analysis was conducted where applicable.

Results:

The review included 30 studies, covering diverse research designs and sample sizes. Key findings included the identification of genetic loci associated with HF, the impact of hypertension and lifestyle factors on HF progression, and the interplay of comorbid conditions such as diabetes in HF management. The studies collectively emphasized the complexity of HF, highlighting its multifactorial nature.

Conclusions:

The findings of this systematic review underscore the multifaceted nature of HF and the need for a comprehensive approach in its management. It points toward the importance of personalized medicine in HF, considering the interplay of various factors. Future research should focus on longitudinal studies with diverse populations to further understand the mechanisms underlying HF and develop targeted interventions.
Periodontal Diagnosis in a Young Patient with an Unusual Presentation of Dental Calculus
Authors: Ababneh Khansa Taha , Nafisah Sultan Al , Maslamani Manal , Al Asiri Turki
Published: January 2025

ABSTRACT

This report details the periodontal diagnosis and phase I treatment of an 18-year-old male patient dissatisfied with his teeth. The patient, on 20 mg Isotretinoin for acne, exhibited heavy calculus and plaque, generalized gingival inflammation, carious lesions, remaining roots, an anterior open bite, bilateral cross-bite, and an ectopically erupted tooth (#25). Initial scaling enabled examination, revealing FMPS and FMBS of 100%, PD of 1–7 mm, gingival recession of 1–2 mm, a maximum CAL of 6 mm, and radiographic bone loss of around 48% of teeth, reaching up to 15% of the root length. Diagnosed with generalized periodontitis (stage II, localized stage III, grade B), treatment involved patient education, scaling, selective root planning, and a long-term maintenance plan. At reevaluation, the patient showed improved oral hygiene, reduced FMPS (33%) and FMBS (11%), fewer pockets, and decreased PD and CAL (deepest CAL now 6 mm). Early periodontal intervention and consistent oral hygiene are critical for subsequent dental treatments.
Spectrum of Brain Imaging with 3T MRI for Infants with History of Perinatal Hypoxia and their Comparison with 128 Slice NCCT Images
Authors: Dwivedi Abhishek , Dakua Anita , Agarwal Mayank , Singh Satyender N. , Choudhury Binoy Kumar , Chaubey Deepika , Chaubey Abhishek
Published: January 2025

ABSTRACT

Background:

Neonates with a history of perinatal hypoxia often require meticulous neuroimaging to detect brain injuries promptly. This study investigates the utility of 3T magnetic resonance imaging (MRI) in assessing neonates with perinatal hypoxia and compares it with the conventional 128-slice NCCT imaging modality.

Materials and Methods:

A retrospective study was conducted, encompassing 67 cases over 1 year from October 2022 to October 2023. We assessed the performance of 3T MRI using the Achieva 3T TX MRI scanner (Philips, The Netherlands) and compared it to the 128-slice GE 660 Optima CT scan.

Results:

We found that 3T MRI demonstrated remarkable sensitivity in detecting brain injuries in this population. Notably, it excelled in identifying subtle lesions, with white matter changes observed in 76.1% of cases, corpus callosum thinning in 64.2%, restriction of diffusion on DWI in 28.4%, signal loss on GRE in 14.9%, and cerebral venous thrombosis in 9% of the study participants.

Conclusion:

The integration of 3T MRI into neonatal neuroimaging protocols is crucial. It offers enhanced diagnostic accuracy and safety, supporting its inclusion as a fundamental component in neonatal care.
A Prospective Study Comparing the Use of Radiometric Measurements in CBCT and DEXA Scans of the Spine to Measure Bone Mineral Density in Postmenopausal Women
Authors: Mallick Sriram Chandra , Bhuvaneshwari S , Sangamesh N.C. , Mishra Silpiranjan , Bajoria Atul Anand , Singh Dhirendra Kumar
Published: January 2025

ABSTRACT

Introduction:

This study evaluated BMD using radiomorphometric indices from conebeam computed tomography (CBCT) scans of the mandible, comparing them with dualenergy Xray absorptiometry (DEXA) scans of the spine.

Results:

The study emphasizes the robustness of DEXAderived T scores for assessing bone health and guiding treatment in postmenopausal women.
Change in the Morphology of Cell Pattern in Oral Mucosa Following Radiation Exposures to Various Radiographic Techniques
Authors: Jena Amrit , Kaur Awneet , Soundarya S , Mahay Pooja , Manohar Balaji , Bhuvaneshwari S.
Published: January 2025

ABSTRACT

Introduction:

Ionizing radiation is extensively utilized in dental imaging research, with radiography serving as the primary diagnostic technique in dentistry.

Materials and methods:

The cytotoxic effects of Xrays are wellestablished, the genotoxic consequences remain debated.

Results:

This study aims to evaluate the impact of dental Xrays on cellular morphological patterns in the oral mucosa.
Assessment of Knowledge, Attitude, and Practice about “SADE” Among Dentists – A Cross-Sectional Study
Authors: Rajendran Madhumathy , Anandhan Vasanthakumari , Arumugam Selvabalaji , Archana S Preethi , Pandiyan Ramanandvignesh , Ramesh Archana
Published: January 2025

ABSTRACT

Background:

Intellectual and developmental disabilities (IDDs), including autism spectrum disorder (ASD), often lead to sensory challenges and dental anxiety, complicating oral healthcare. Sensory adapted dental environment (SADE) can alleviate anxiety and enhance cooperation during dental procedures, but awareness and implementation among dentists remain limited.

Objective:

To assess general dentists’ knowledge, attitudes, and practices regarding SADE and identify gaps for targeted educational programs.

Methods:

A survey of 500 dentists in Tamil Nadu, India, collected data on demographics, SADE knowledge, attitudes, and practices. Analysis included descriptive statistics and significance tests.

Results:

Most respondents were female (68.6%), aged 21–30 (90.9%), with a BDS degree (76.0%), and having 1–10 years of experience (94.8%). Primary fears for children in dental settings were injections (45.7%) and white coats (41.8%). Nonpharmacologic techniques were preferred by 86.8% of dentists. While 49.5% were aware of SADE, only 30.3% had implemented it. Most recognized its benefits (78.7%) and believed it reduces anxiety (81.9%). Despite interest (84.7%), concerns about costs (53.0%) hindered implementation.

Conclusion:

Strong interest and perceived benefits of SADE exist among dentists, but cost concerns and limited understanding hinder its implementation. Enhanced education and resources are vital for broader SADE adoption, potentially improving dental care for individuals with IDDs.
Evaluation of the Transverse Strength and UV Spectrophotometric Analysis of the Residual Monomer Content of Autoclave Polymerized Conventional and High-Impact Heat-Cure Denture Base Resins—An In-Vitro Study
Authors: Roseline Savarimuthu Paulraj , Mathew Chalakuzhiyil Abraham , Gnanavel S Sakthi , Vengatachalam Vishnuvardhan , Kittuchami Dheepika , Gopalakrishnan Priyanka
Published: January 2025

ABSTRACT

Background and Objective:

Inspite of advancements in material properties of heat cure acrylic resin, fracture of denture base and allergic reactions due to release of residual monomer is encountered frequently. To improve strength and to reduce residual monomer, different polymerization methods need to be investigated. The objective is to evaluate and compare transverse strength and residual monomer content of two different heat cured denture base resins polymerized by conventional water bath and by autoclave.

Materials and Methods:

Samples were prepared with Acralyn-H conventional heat cure resin and Acralyn-H super hi-impact resin using metal dies. Samples undergoing water bath polymerization were polymerized in water bath at 74°C for 2 hours followed by 100°C for 1 hour and samples undergoing autoclave polymerization were cured in an autoclave at 121°C and 210 kPa for 30 minutes as holding temperature. Transverse strength specimens were processed and then tested for transverse strength in a Universal testing machine. Specimens for residual monomer content estimation were weighed and each specimen’s residual monomer was extracted in methanol using Soxhlet extractor and then read at 230nm in Ultraviolet-Visible spectrophotometer. Concentrations of residual monomer were evaluated and weight fractions were calculated.

Results:

The results of this study showed a statistically significant difference in transverse strength of Acralyn-H conventional heat cure resin polymerized by autoclave, whereas all other groups showed a non-significant result.

Conclusion:

Autoclave can be used as an alternative polymerization technique as it has shown similar results when compared with water bath polymerization and the time required for polymerization was also reduced.
Human Papillomavirus Vaccination in Saudi Arabia: A Narrative Review of Current Evidence
Authors: Alqahtani Abdulrahman M. M. , Alshahrani Mohammed S. S. , Almajed Ebtesam , Salamah Rawan A. Bin , Alqntash Norah , Biju Amina M. , Meem Mohima S. , Pullishery Fawaz
Published: January 2025

ABSTRACT

Human papillomavirus (HPV) represents the most common sexually transmitted infection globally, exerting a substantial impact on sexual and reproductive health, with a high oncogenic potential leading to various malignancies. The prevalence of HPV in Saudi Arabia ranges from 9% to 43%, with types 16, 18, and 45 being the most common high-risk strains. Despite the availability of effective vaccines such as Gardasil 9, Gardasil, and Cervarix, proper awareness and vaccination rates remain low in Saudi Arabia. Only 4% of the population has received the HPV vaccine. The Saudi Ministry of Health has integrated HPV vaccines into the national immunization schedule, offering them free of charge and ensuring their availability for adolescent girls and women. However, challenges persist, including cultural and religious beliefs, inadequate healthcare infrastructure, and insufficient public awareness. To effectively increase HPV vaccination coverage, it is crucial to implement comprehensive public education campaigns, actively involve healthcare professionals, and address cultural and religious concerns with sensitivity and respect. International collaboration, such as initiatives by the Gavi alliance and sustained research efforts, is critical to optimizing HPV vaccine efficacy, accessibility, and uptake. Through coordinated efforts, the global burden of HPV-related diseases can be significantly reduced, ultimately leading to improved public health outcomes.
Determination of Phytochemical Properties “Amman Pacharisi”–Euphorbia hirta Linn
Authors: Subramani Prabhu , Murugappan Senthil , Ganesh Gajalakshmi , Jones Sumathi , Mani Devi
Published: January 2025

ABSTRACT

Background:

Euphorbia hirta is a common roadside weed seen in many parts of India. The aim of the present study is to determine and isolate the bioactive compounds, by GC-MS analysis, which successively will then serve to develop “Phytotherapy” for various ailments among human beings using the Euphorbia hirta plant.

Materials and Methods:

The Euphorbia hirta plant is sundried and powdered, and the powder is subjected to soxhlet extraction with ethanol as solvent. The crude extract obtained is subjected to gas chromatography and mass spectroscopy. Mass spectra were obtained over the scan range of m/z 40–600. The compounds were identified by comparison of their mass spectra with those of the NIST 05 L mass spectral library.

Results:

More than 20 biologically active components were identified using GC-MS analysis. Anti-microbial effects are seen due to heneicosane, methyloctosane, tetracosane, and beta sitosterol. The Anti-inflammatory effect is attributed to n-Hexadeconoic acid, hexacosane, alpha-amyrin, and beta-amyrin. Extracts possess antioxidant effects due to the presence of vitamin E and squalene.

Conclusion:

The crude ethanolic extract of Euphorbia hirta possess analgesic, anti-inflammatory, anti-microbial, anti-oxidant, anti-cancer, anti-diabetic, and anti-lipidemic effects. This herb can serve as a potential source of medicine.
Comparative Efficacy of Different Interventional Methods on Salivary pH
Authors: Lakshmikumari K. , Rajesh Kavitha , Jayaraj Merlin , Prasad Vishnu , Nagappan Nagappan , Nyklesh V.
Published: January 2025

ABSTRACT

Aim:

To evaluate and compare the efficacy of four interventional methods (water rinsing, brushing with water, brushing with non-fluoridated dentifrice, and brushing with fluoridated dentifrice) in maintaining the salivary pH after an acidic surge.

Background:

Salivary pH plays an important role in caries formation and progression; even though there are many interventional methods available for oral hygiene measures, not many studies reveal the potency of the various interventional methods after an acidic surge.

Materials and Methodology:

Forty-three children of age group 4-5 years were selected for this study. The unstimulated saliva was collected using Dawe’s method in sterile containers and pH was measured using color coded pH strips. The mean value was calculated, tabulated, and statistically analyzed using analysis of variance (ANOVA) and paired t-test.

Results:

A significant increase was seen in the salivary pH, when brushing was performed using fluoridated and non-fluoridated tooth paste (P = 0.00) compared to that of brushing without dentifrice and water rinsing groups.

Conclusion:

The study concluded that water can be used as an intermediate intervention to revert the salivary pH until a definitive intervention like toothbrush and dentifrice is available. Tooth brushing with dentifrice is the better home care interventional method to succumb the salivary fall.
Exploring the Antibacterial and Antifungal Efficacy of Herbal Plants: An Ayurvedic Research
Authors: Balaraman Gajapathi , Vijay V. M. Jerbin , Gracy P. Joanna , Kumar S. Arul , Vishali S. , Harish G.
Published: January 2025

ABSTRACT

Context:

Nature has endowed humanity with a vast repository of remedies that have been use for ages to heal all sorts of ailments.

Aim:

To evaluate the antibacterial and antifungal efficacy of three herbal plants (Justicia adhatoda, Glycyrrhiza glabra, and Punica granatum), on three microorganisms (Streptococcus mutans, Staphylococcus aureus, and Candida albicans) that are present in the oral stoma.

Settings and Design:

In vitro microbial study.

Methods and Material:

Extracts of 0.3 mg/ml, 0.6 mg/ml, 1.25 mg/ml, 2.5 mg/ml, 5.0 mg/ml, and 10.0 mg/ml were prepared from leaves of Justicia adhatoda, barks of Glycyrrhiza glabra, and fruits of Punica granatum, respectively. The antibacterial and antifungal efficacies of the extracts were evaluated by agar well diffusion method and their resultant zone of inhibition.

Statistical Analysis Used:

One-way ANOVA test and Tukey HSD post-hoc test.

Results:

The order of antimicrobial efficacy observed in increasing order—Glycyrrhiza glabra < Justicia adhatoda < Punica granatum. Higher the concentration of plant extract, increased the zone of inhibition.

Conclusion:

The extracts of Justicia adhatoda, Glycyrrhiza glabra, and Punica granatum were found to be effective against oral pathogenic microorganisms.
Augmented/Virtual Reality in Dermatology: A Digital Arsenal in Modern Era
Authors: Meghe Soham R. , Ramapure Raavi , Quazee Sabiha , Singh Adarshlata , Jawade Sugat
Published: January 2025

ABSTRACT

Introduction:

Augmented reality (AR) refers to a group of technologies that capture, analyze, and superimpose digital information onto the real world. This information gives health care providers unique and useful perspectives that can enhance patient care.

Materials and methods:

AR has been utilized in selected scenarios in health care for several decades, notably laparoscopic surgery and vein finding. In recent years, improved wireless technologies, computing power, and analytics are leading to rapid growth in the AR industry. Novel health care specific use cases are rapidly being introduced with the potential to widely affect clinical care, particularly in dermatology because of the visual nature of the field.

Results:

In this article, we define AR, profile clinical and educational uses of AR in dermatology, and discuss key policy considerations for the safe and appropriate use of this emerging technology.
Assessment of Orthofacial Analysis in Indigenous Tribes: A Cross-Sectional Study
Authors: Fathima Lubna , Narmadha D , Suganya P , Subramani Manimala , Prabhakar Soundarya , Pavithra R.
Published: January 2025

ABSTRACT

Background:

The indigenous tribes still exist in our Chennai, which found quite interesting for us to conduct a survey on the prevalence of malocclusion and facial symmetry. AIM: This study aims to assess the prevalence of malocclusion and facial symmetry in indigenous tribes: the narikurava. Setting and design: The study was a cross-sectional survey.

Material and Methods:

One hundred and twenty-one individuals participated in the study. The prevalence of malocclusion was assessed as normal occlusion, class 1, class 2 and class 3 occlusion, and facial symmetry was recorded along with facial aesthetic index.

Statistical Analysis:

Descriptive statistics were calculated for all the variables recorded in our study, and chi-square test was done to find the association between the gender and facial aesthetic index.

Results:

Among the indigenous tribes, 33.9% had normal occlusion, 31.4% had class 1 occlusion, 14.9% had class 2 div 1 occlusion, 9.1% had class 2 div 2 occlusion, and 10.7% had class 3 occlusion. Males had a higher percentage of normal occlusion than compared to females.

Conclusion:

Even an infant wants to have a good smile which is aesthetic in nature; here, in the survey conducted more than 30% of individuals were having a normal occlusion, and only about 9% individuals were having class 2 division 2 which is least occlusion seen among the indigenous tribes.
Role of phage therapy in acute gastroenteritis
Authors: Sabzali Somaieh , Pazhouhnia Setareh , Shahzamani Kiana , Sedeh Peyman Adibi
Published: January 2025

The gut ecosystem, comprising the gut microbiota and its interactions, plays a crucial role in human health and disease. This complex ecosystem involves a diverse array of microorganisms such as viruses, fungi, and bacteria, collectively known as the gut microbiota. These microorganisms contribute to various functions, including nutrient metabolism and immune modulation, thereby impacting human health. Dysbiosis, or an imbalance in the gut microbiota, has been associated with the pathogenesis of several diseases, ranging from intestinal disorders such as inflammatory bowel disease to extra-intestinal conditions such as metabolic and neurological disorders. The implications of dysbiosis in the gut ecosystem are far-reaching, affecting not only gastrointestinal health but also contributing to the development and progression of conditions such as autoimmune gastritis and gastric cancer. Furthermore, the burden of antimicrobial use and subsequent side effects, including antibiotic resistance, poses additional challenges in managing gastrointestinal diseases. In light of these complexities, investigating the role of bacteriophages as regulators of the gut ecosystem and their potential clinical applications presents a promising opportunity to tackle antibiotic resistance and fight infectious diseases.
PRINCIPAIS DESAFIOS NA ELABORAÇÃO DO PROJETO POLÍTICO PEDAGÓGICO NAS INSTITUIÇÕES PÚBLICAS NO TERRITÓRIO BRASILEIRO
Authors: Peixoto Lucélia Paiva , Silva Ivaneide Francisca Santos da , Silva Paula Francinete Santos da , Guerra Avaetê de Lunetta e Rodrigues
Published: January 2025

A justificativa desta investigação deve-se ao interesse pessoal e profissional em aprofundar os conhecimentos relacionados ao tema: Investigar a Gestão participativa para uma escola democrática, em instituições públicas no território brasileiro. Neste sentido, destacamos a importância do ensino com qualidade na atualidade, pois representa uma forma de trazer melhores perspectivas para os estudantes. Assim, conclui-se que nosso sistema de educação precisa estar voltado a preparação dos alunos para o futuro e não apenas a buscar passar os assuntos relativos à matéria, pois não adianta ter domínio de algo, sem saber usar as potencialidades de um determinado conhecimento.
Pensamiento crítico reflexivo desde la experiencia docente
Authors:   Universidad Femenina del Sagrado Corazón, Huillca Condori Bertha Judith , Rodríguez Saavedra Liliana ,   Universidad Femenina del Sagrado Corazón
Published: January 2025

El pensamiento crítico del docente universitario desempeña un rol importante en el proceso de enseñanza y aprendizaje. El sistema de concepciones y creencias determinan la acción educativa del formador. Este estudio tuvo como objetivo analizar las concepciones y prácticas pedagógicas del pensamiento crítico reflexivo desde la voz del docente en el contexto de una Institución educativa universitaria. De enfoque cualitativo y de tipo estudio de caso. Mediante un muestreo por conveniencia se desarrollaron entrevistas semi estructuradas a seis docentes y se analizaron las concepciones de los docentes a través del software Atlas. Ti 9. Las conclusiones fueron: Las concepciones de los docentes están asociadas al desarrollo de competencias cognitivas prevaleciendo los procesos de lectura y procesos investigativos. Asimismo, en una línea complementaria aluden al carácter actitudinal del pensamiento. Las prácticas pedagógicas están asociada a competencias cognitivas y principios pedagógicos con tendencia constructivista, no existiendo unicidad en los fundamentos que orientan el desarrollo de dicho pensamiento.
Diseño de Experimentos como Estrategia de Innovación Organizacional en la Industria de Celulosa
Authors:   Instituto Tecnológico de Sonora, Mendoza-León Jorge Guadalupe , García-Ochoa Juan José ,   Universidad de Sonora, Núñez Luna Mario Alberto ,   Instituto Tecnológico de Sonora
Published: January 2025

La innovación organizacional genera valor para las empresas, particularmente para el sector industrial. Así, la aplicación del diseño experimental como metodología para la innovación organizativa, resulta pertinente al abordar problemas de desempeño de la calidad en los procesos de moldeo y secado en una planta industrial de producción de celulosa. El objetivo fue determinar los factores principales de influencia y los parámetros óptimos para cada uno de los procesos estudiados, mediante el modelo de diseño de experimentos conocidos como 2k, específicamente factorial 23 y 24 (dos niveles con tres factores y dos niveles con cuatro factores), para los procesos de moldeo y secado, respectivamente. La ruta metodológica utilizada sigue las pautas generales para diseñar un experimento. Los hallazgos indican que, de acuerdo a las variables de respuesta, se encontraron los parámetros que, al ajustarlos en el equipo, mejoran el desempeño de las variables de respuesta peso húmedo de la charola para el subproceso de moldeo y para el subproceso de secado es el peso de la charola seca. En conclusión, dado que el proceso tiene constantes cambios en sus parámetros, los operadores o jefes de turno dependen de las muy variables fluctuaciones de la concentración de la pasta, se hace necesario que, en un segundo momento, se establezca un procedimiento estándar que asegure el cumplimiento de los parámetros diseñados para el mejor desempeño de los subprocesos, en la fabricación del producto de nombre “cartera de huevos Maxi”.
Propuesta multi y transdisciplinaria para una escuela - restaurante de la Universidad Rosario Castellanos, ciudad de México
Authors:   Universidad Rosario Castellanos, Pérez Davalos Norma Rocío , Oliva Aguilar Víctor Ramón ,   Instituto Politécnico Nacional, Gutiérrez García Grace Viridiana ,   Universidad Rosario Castellanos, Franco Cortés Everardo Francisco ,   Universidad Rosario Castellanos
Published: January 2025

La Universidad Rosario Castellanos (URC) cuenta con tres modelos educativos Híbrido Dual, Presencial Híbrido y a Distancia Híbrido y la implementación del enfoque basado en la resolución de problemas prototípicos, dado por este tipo de enseñanza, surge el siguiente objetivo de la presente investigación que es proponer un acercamiento que pueda contribuir a la aplicación de un modelo de Restaurante-Escuela que involucre en particular a las licenciaturas en: Turismo, Administración y Comercio, Mercadotecnia y Ventas, Contabilidad y Finanzas y Ciencia de Datos para Negocios, aborda una aproximación teórica. Esta se fundamentó con la metodología explicativa y la revisión bibliográfica sobre la literatura de la educación multidisciplinaria y transdiciplinaria, así como el modelo educativo de la URC. Para poder alcanzar el objetivo, se realizó de manera cualitativa y transversal el análisis de los 5 programas académicos, analizando un total de 241 asignaturas documentando de forma exploratoria y descriptiva las áreas de convergencia que aproveche las sinergias y permita abordar el objeto de estudio, desde la perspectiva multi y transdisciplinaria, obteniendo como resultado la factibilidad de este desde la perspectiva pedagógica. Dando como resultado que el proyecto no solo beneficiará a los estudiantes al ofrecer experiencias prácticas, propiciando el fomento a la colaboración entre distintas disciplinas, sino que también tendría un impacto significativo en la comunidad local, ya que al contar con una Restaurante-Escuela con una oferta gastronómica bien diseñada y a un precio razonable, se colocaría como pionera al conjuntar tanto saberes como disciplinas para la atención de un problema comunitario real.
Responsabilidad social corporativa en la innovación y competitividad: un enfoque en la gestión del conocimiento organizacional
Authors:   Tecnológico de Antioquia Institución Universitaria, Galviz Cataño Diego Fernando , Rico Buitrago Jesús Daniel ,   Tecnológico de Antioquia Institución Universitaria, Correa Wachter Juan Fernando ,   Tecnológico de Antioquia Institución Universitaria, Corrales Mosquera Bresman ,   Corporación Universitaria La Americana, González-Rubio Villa Melissa ,   Corporación Universitaria La Americana
Published: January 2025

El objetivo de esta investigación fue analizar la influencia de la responsabilidad social corporativa (RSC) en la innovación y competitividad, con un enfoque en la gestión del conocimiento organizacional en PYMEs. Se utilizó una metodología cuantitativa de tipo descriptivo, donde se aplicó una encuesta a 47 personas de diferentes empresas para evaluar la integración de la gestión del conocimiento en la estrategia corporativa y su impacto en la sostenibilidad y los beneficios tangibles. La metodología consistió en el uso de un cuestionario con preguntas cerradas, analizando las respuestas mediante estadísticas descriptivas. Los resultados mostraron que la mayoría de las empresas integran la gestión del conocimiento en su estrategia, con un fuerte apoyo de la alta dirección. Además, se observó que la gestión del conocimiento contribuye significativamente al logro de los objetivos estratégicos, fomenta la innovación y mejora la competitividad. En conclusión, la RSC, cuando se gestiona adecuadamente, puede ser un motor clave para la innovación y competitividad en las PYMEs, destacando la importancia de integrar la gestión del conocimiento en las prácticas corporativas. Se concluye que la integración de estas prácticas no solo mejora la eficiencia y competitividad, sino que también fortalece la sostenibilidad a largo plazo de las empresas.
NIIF 16 de arrendamiento: evidencia de las experiencias de los consultores empresariales
Authors:   Corporación Universitaria Americana, Castellanos Polo Orlando Carmelo , Velásquez Ochoa José Alexander ,   Corporación Universitaria Americana, Corrales Mosquera Bresman ,   Corporación Universitaria Americana, Galviz Cataño Diego Fernando ,   Tecnológico de Antioquia Institución Universitaria, Rico Buitrago Jesús Daniel ,   Tecnológico de Antioquia Institución Universitaria
Published: January 2025

Este articulo analiza las experiencias de los consultores de las empresas de los sectores económicos categorizados aquellas del grupo número uno que cotizan en la bolsa de valores, sobre la implementación de las NIIF (Normas Internacionales de Información Financiera) 16 de arrendamiento y sus enmiendas en el tiempo de pandemia del COVID 19, con las nuevas restricciones del reconocimiento para la presentación de los estados financieros, del análisis realizado se plantearon los siguientes temas: 1) cual es el concepto de los consultores de empresas en la actualización de la NIIF 16, 2) como fue la participación de las nuevas directrices en la presentación de los estados financieros con respecto al COVID 19, el trabajo se desarrolló bajo un enfoque cualitativo, desde el método fenomenología, la información se obtuvo mediante entrevistas aplicando encuestas de preguntas abiertas a un total de veinte profesionales con el cargo de socio que ejercen su profesión en firmas de auditoría y consultoría empresarial, adicionalmente se hizo una revisión documental de los documentos de debate de la NIIF 16 del gremio contable, los resultados de la investigación proporcionan a las universidades y a las futuras investigación que se desarrollen sobre este planteamiento las perspectivas del contexto de las NIIF frente a los Estados financieros, y de la importancia de estar actualizados en la profesión.
Conformación del suelo del departamento de la guajira: un análisis desde la cosmogonía de la comunidad indígena Wayuu
Authors:   Universidad Popular del cesar, Jiménez Lobo Dina Luz , Núñez Quiñones Juan Camilo ,   Universidad Popular del Cesar, Guerrero Durán Juan Andrés ,   Universidad Popular del Cesar, Gutiérrez De Piñeres Orozco Jesús ,   Universidad Popular del Cesar, Solano Cabarcas Miguel José ,   Universidad Popular del Cesar
Published: January 2025

La conformación de los suelos en torno a factores como humedad, temperatura y biodiversidad tiende a influir en la estructura social, en el desarrollo económico y la preservación de grupos étnico-propios de un territorio, por lo que la cosmogonía indígena se convierte en elemento clave para explicar el origen de la naturaleza desde un enfoque de espiritualidad. Por tal motivo, se logró analizar la conformación del suelo del departamento de La Guajira desde la cosmogonía de la comunidad indígena Wayuu, teniendo en cuenta el contexto científico y antropológico del territorio, abordando con un tipo de investigación con enfoque cualitativo bajo un alcance descriptivo y un diseño de investigación de tipo etnográfico, aplicando como técnica una revisión documental y una entrevista a tres expertos de la comunidad indígena wayuu. Teniendo en cuenta lo anterior, Se logró evidenciar que, desde su concepción de la vida, ellos consideran que las condiciones fisicoquímicas del suelo, el clima y el relieve son el resultado de la unión de dos mundos, el espiritual (jüyá- Dios de la lluvia) y el terrenal (M´ma- madre tierra), creados por un ser supremo llamado Maleiwa, permitiendo el pleno desarrollo de los clanes de acuerdo con sus capacidades. concluyendo de esta manera, que la cosmogonía Wayuu explica cada una de las características propias en materia de suelo desde un enfoque espiritual.