bluuebunny/crossref_metadata_2025 huggingface dataset:
Penghayatan Dakwah Akhlak Di Kalangan Pelajar Sekolah Menengah Negeri Perak
Authors: Othman Mohd Syaubari , Yusuf Abu Bakar Yusuf , Hosshan Hasrul , Mohamed Hashim Abdul Talib
Published: October 2023

Konteks pembangunan ekonomi dan politik di dalam sesebuah negara, pembinaan akhlak dalam bentuk pembangunan manusia yang seimbang dan bersepadu akan menjamin pembangunan ekonomi yang mampan serta kekuatan politik yang akan menjamin kecemerlangan negara secara berterusan. Atas kesedaran tersebut, kepentingan akhlak sebagai suatu gagasan bagi menjamin pembangunan negara yang mampan dan seimbang dinyatakan dengan jelas sebagai salah satu di antara cabaran Pelan Pembangunan Pendidikan 2013-2025. Pada masa yang sama, pelbagai dasar, sistem, perancangan strategik dan program yang dilaksanakan dalam amalan pendidikan di negara ini memberikan gambaran yang jelas terhadap komitmen pihak kerajaan untuk melahirkan generasi rakyat Malaysia yang memiliki keperibadian yang mulia dan seimbang. Namun, status sebenar penghayatan akhlak di kalangan pelajar sekolah menengah di Negeri Perak yang telah melalui sistem pendidikan di negara ini masih menjadi tanda tanya. Dapatan dari satu kajian tinjauan menunjukkan status keseluruhan penghayatan akhlak peribadi di kalangan pelajar sekolah menengah adalah pada tahap sederhana tinggi. Dapatan ini seterusnya menggambarkan pola penghayatan yang agak sederhana dalam beberapa aspek akhlak di kalangan pelajar sekolah menengah seperti personaliti kendiri, amalan seharian dan pengetahuan mengenai akhlak. Pendekatan kaedah tinjauan ini menetapkan daerah Manjung sebagai fokus utama dengan pembahagian kepada tiga pola utama iaitu pelajar yang mengikuti KAA, pelajar Islam yang mengikuti pembelajaran di SMJK (C) dan pelajar di SMK Harian. Dapatan mungkin memberikan sedikit gambaran tentang punca kepada beberapa masalah sosial yang dihadapi dalam masyarakat masa kini. Beberapa prospek penyelidikan turut dicadangkan bagi meneliti dengan lebih mendalam terhadap penghayatan akhlak di kalangan pelajar sekolah menengah khususnya di Negeri Perak
Persatuan Belia Islam Nasional (Pembina): Penggerak Pelestarian Dakwah dan Pembangunan Modal Insan Holistik Mahasiswa
Authors: Jamadon Nashrah Hani , Ramli Muhammad Imran Hakimi , Shaikh Sukor Shaikh Muhammad Afiq , Abdulllah Aznur Aisyah , Misran Norbahiah
Published: October 2023

Penarafan institusi pengajian tinggi (IPT) di Malaysia dalam kedudukan universiti dunia Quacquarelli Symonds (QS) menunjukkan peningkatan positif dalam bilangan mahasiswa dan kualiti pendidikan negara. Walau bagaimanapun, isu kebolehpasaran di kalangan graduan sebaik sahaja tamat pengajian semakin memimbangkan dan perlu diberi perhatian. Penglibatan secara aktif mahasiswa dalam kegiatan persatuan pelajar dilihat mampu menyelesaikan masalah ini. Persatuan Belia Islam Nasional (PEMBINA) merupakan persatuan belia kebangsaan yang berdaftar di bawah Pendaftar Persatuan Belia, Kementerian Belia dan Sukan, dan mempunyai cawangan di IPT seluruh negara. Kajian ini memfokuskan peranan PEMBINA di Universiti Kebangsaan Malaysia (UKM) dalam menghasilkan modal insan yang holistik melalui program bersifat dakwah. Kajian ini dijalankan menerusi tinjauan menyeluruh program bantuan ‘Siswa Meal Box’ yang dilaksanakan oleh warga kerja PEMBINA. Kajian kualitatif menggunakan instrumen dokumentasi, reflektif jurnal dan borang soal selidik sebelum dan selepas mengadakan program telah direka bentuk. Perisian ATLAS.ti® versi 8 digunakan untuk menganalisis kaji selidik dan temu bual tidak berstruktur dijalankan bagi meninjau  persepsi responden terhadap program yang dikendalikan. Responden kajian terdiri daripada ahli PEMBINA yang merupakan ahli jawatankuasa program seramai 25 orang. Analisis mendapati penganjuran program mengikut model PEMBINA telah melatih kemahiran ahlinya dari aspek komunikasi, interaksi sosial, kepimpinan, dan semangat kerja sepasukan. Kemahiran ini mampu membentuk mahasiswa yang proaktif, yang penuh dengan nilai-nilai positif seterusnya meningkatkan daya saing serta kebolehpasaran dalam pekerjaan
Pelatihan Problem Solving Pada HMJ Teknik Informatika UIN Alauddin Makassar Menggunakan Metode Computational Thinking
Authors: Syafaat Muhammad
Published: October 2023

Organisasi kemahasiswaan merupakan suatu wadah aktualisasi diri para mahasiswa dalam tataran perguruan tinggi, baik itu pada organisasi kemahasiswaan internal kampus maupun eksternal kampus. Dalam perjalananya organisasi kemahasiswaan kerap dipertemukan pada sejumlah permasalahan, dalam hal ini khsusnya pada Himpunan Mahasiswa Jurusan Teknik Informatika UIN Alauddin Makassar yang menjadi wadah pengembangan diri para mahasiswa juga kerap menghadapi masalah dalam organisasi. Sehingga dibutuhkan suatu metode khusus dalam problem solving pada HMJ TI UINAM yang mempunyai korelasi dengan identitas jurusan teknik informatika yaitu metode computational thingking, Maka dari itu dilaksanakan kegiatan pengabdian kepada masyarakat yang dikemas dalam bentuk Upgrading pengurus HMJ TI UINAM untuk mencoba menerapkan metode ini pada organisasi kemahasiswaan dimana diharapkan para pengurus HMJ TI UINAM mendapatkan pengetahuan baru dalam menghadapi masalah dalam organisasi. Setelah pengabdian ini dilaksanakan didapatkan bahwa para pengurus sangat antusias dalam melakukan role play dalam pelatihan sehingga mereka telah mengetahui metode computational thinking dapat diterapkan dengan baik dalam memecahkan masalah dalam organisasi
Abstract
Student organizations are a forum for self-actualization of students at the tertiary level, both in internal and external campus student organizations. In its journey, student organizations often encounter a number of problems, in this particular case the Student Association of the Informatics Engineering Department of UIN Alauddin Makassar which is a place for self-development for students who also often face problems in the organization. So that a special method is needed in problem solving at HMJ TI UINAM which has a correlation with the identity of the informatics engineering department, namely the computational thinking method. Therefore, community service activities are carried out which are packaged in the form of Upgrading the management of HMJ TI UINAM to try to apply this method to student organizations where it is hoped that the management of HMJ TI UINAM will gain new knowledge in dealing with problems in the organization. After this service was carried out, it was found that the administrators were very enthusiastic in doing role play in the training so that they already knew that computational thinking methods could be applied well in solving problems in organizations.
Pelatihan Penulisan Artikel Ilmiah Pada Mahasiswa Semester Akhir
Authors: Muhammad Yahrif  , R. Supardi
Published: October 2023

Pelatihan penulisan artikel ilmiah merupakan salah satu hal yang sangat penting diketahui oleh mahasiswa semester akhir. Publikasi artikel ilmiah merupakan salah satu syarat yang harus dipenuhi oleh mahasiswa semester akhir sebelum mereka maju untuk ujian akhir. Tapi berdasarkan observasi awal dengan beberapa mahasiswa semester akhir, ternyata masih banyak diantara mereka tidak tahu cara penulisan artikel ilmiah. Bahkan ada diantara mereka beranggapan bahwa penulisan artikel ilmiah sama dengan penulisan tugas makalah biasa. Berdasarkan temuan tersebut maka perlu diadakan pelatihan penulisan artikel ilmiah pada mahasiswa semester akhir. Pengabdian kepada masyarakat ini menggunakan metode deskriptif. Diharapkan dengan adahnya pelatihan penulisan artikel ilmiah ini dapat membantu mahasiswa semester akhir untuk menulis dan mempublikasikan artikel ilmiah mereka, sehingga mereka dapat memenuhi salah satu pra syarat kelulusan studi mereka.
Abstract
Training in writing scientific articles is one of the things that is very important for final semester students to know. The publication of scientific articles is one of the requirements that must be met by final semester students before they advance for the final exam. But based on preliminary observations with several final semester students, it turns out that there are still many of them who don't know how to write scientific articles. Some of them even think that writing scientific articles is the same as writing ordinary paper assignments. Based on these findings, it is necessary to hold scientific article writing training for final semester students. This community service used a descriptive method. It is hoped that this scientific article writing training can help final semester students to write and publish their scientific articles, so that they can fulfill one of the pre-requirements for graduating from their studies.
Pendampingan Implementasi Kurikulum Meredeka Melalui Pelatihan Komite Pembelajaran Sekolah Penggerak
Authors: Yahrif Muhammad , R. Supardi
Published: October 2023

Implementasi kurikulum merdeka di tahun ketiga pelaksanaan menjadi salah satu upaya pemerintah dalam mempercepat proses perbaikan dan transformasi pendidikan di Indonesia ke arah yang lebih baik. Dalam penerapannya tentu perlu dipahami oleh seluruh komite pembelajaran sebagai pemeran utama pelaksana kurikulum merdeka. Artikel pengabdian kepada masyarakat ini memaparkan hasil pelaksanaan Pelatihan Komite Pembelajaran (PKP) Implementasi Kurikulum Merdeka (IKM) di Komite Pembelajaran yang ada pada dua sekolah penggerak di Kabupaten Soppeng. Pelaksanaan PKP ini melalui empat tahap yakni: 1) pemberian materi IKM melalui pelatihan aksi nyata, 2) pendampingan merancang pembelajaran, 3) implementasi projek penguatan profil pelajar pancasila yang telah disusun, dan 4) feedback atau monitoring kegiatan. Hasil feedback dan monitoring kegiatan PKM menunjukan bahwa 85% peserta menjawab sangat setujuh terkait pemaparan materi dan diskusi sudah cukup untuk membuat pemahaman para peserta pelatihan, 95% peserta pelatihan menjawab sangat setujuh atas pemahaman mereka sangat meningkat setelah mengikuti kegiatan pelatihan ini, dan 100% peserta pelatihan menjawab sangat setujuh atas materi yang dipaparkan sesuai dengan kebutuhan mereka
DOĞAL RADYASYONUN YÖNETİMİYLE TASARLANAN KİŞİSEL TERMAL YÖNETİM SAĞLAYAN PASİF AKILLI YAPILAR
Authors: Kaplan Sibel , Korkmaz Memiş Nazife
Published: October 2023

Kişisel termal yönetimin sağlanmasına yönelik, değişen vücut ve çevre şartlarına adapte olabilen pasif ve aktif akıllı tekstil yapıları ile artırılmış konfor ve azalan enerji gereksinimi gibi konularda avantajlar sağlanabilmektedir. Bu çalışmada, dünya için gün geçtikçe önem kazanan enerji kısıtlarına bağlı olarak, ekstra enerji harcanmadan doğal radyasyon enerji bileşenleri (ultraviyole, görünür, infrared) ve mekanizmalarının (yayılım, yansıtma, absorpsiyon, geçirgenlik) yönetimiyle vücudun termal dengesini ısıtma/soğutma veya ısıtma-soğutmayı birlikte sağlayarak koruyan yapılar, etkili radyasyon ısı transfer mekanizmaları ışığında incelenmiştir. Bu tür pasif akıllı yapılar için kullanılan ölçüm yöntemleri, mevcut çalışmaların eksik noktaları ve ilerleme yönü konularında da literatür ışığında değerlendirmeler yapılmıştır. Mevcut çalışmaların son dönemde, küresel ısınmanın etkilerinin de somut olarak hissedilmesiyle birlikte, radyasyonla iç ortamlarda kişisel soğutma konusunda yoğunlaştığı, dış ortamda geçerli olan karmaşık mekanizmaların tasarım ve ölçümleri zorlaştırdığı sonucuna varılmıştır. Ayrıca, çalışmalarda yapıların giyilebilirlikleri açısından önemli olan tutum, konfor ve radyasyon dışındaki ısı ve kütle transfer mekanizmalarının bütüncül olarak incelenmeleri konusunda eksiklikler tespit edilmiştir. Çalışmalar, konfor ve enerji tasarrufu beklentilerinin hızla değiştiği günümüzde radyasyon enerjisi yönetimiyle ısıtma/soğutma yapan yapıların vücut ve ortam koşullarına otonom olarak uyum sağlayabilecek şekilde tasarlanması yönünde ilerlemektedir.
COMPARATIVE ANALYSIS OF EMBROIDERY AND SCREEN-PRINTING TECHNIQUES FOR TEXTILE-BASED FREQUENCY SELECTIVE SURFACES
Authors: Üner İbrahim , Can Sultan , Gürcüm Banu Hatice , Yılmaz Asım Egemen , Aksoy Ertuğrul
Published: October 2023

Frequency Selective Surface (FSS) is a specialized structure used in the field of electromagnetic waves and radio frequency (RF) engineering. It is designed to exhibit selective transmission or reflection properties based on the frequency of the incident electromagnetic waves. This article describes the design, construction, and analysis of a textile-based band-stop frequency selective surface for use in the highly EM-polluted GSM, Wi-Fi, LTE, and WiMAX bands. A full-wave EM solver called CST Microwave Studio was used to develop and simulate the unit cell of the proposed FSS at the relevant frequency. In this study, embroidered and screen-printed textile based FSSs were designed. According to the results of this study, it was demonstrated that both embroidery and screen printing FSSs exhibit resonance at a frequency of 3.5 GHz. The screen printing method yielded the best results in terms of resonance frequency sensitivity, while the embroidery method showed a resonance frequency shift. It was observed that the stitch directions and density are important parameters in the embroidery method. Gaps between the embroidery paths in the production of embroidered FSSs resulted in differences from simulations due to the disruption of the structural integrity of the unit cell. Consequently, textile-based FSSs offer advantages over traditional FSSs. This study highlights the potential of textile FSSs as an effective means of reducing electromagnetic pollution, and suggests that further improvements in the design and production processes of textile FSSs can be made.
The concept of the Center for psychological support of resident doctors during the training period.
Authors: Tuillet Polina Sergeevna
Published: October 2023

Taking into account the importance of the profession of medical workers and the need of citizens for affordable, timely and high-quality medical care, it is necessary to develop a set of organizational and psychological measures aimed at preserving the mental health and well-being of medical workers. At the same time, the primary importance is the protection of the psychological health of resident doctors who are at the initial stages of their careers, since not only correction, but also prevention of emotional disorders is possible during this period. The subject of the study is the organization of psychological assistance to resident doctors during the training period, as well as approaches to psychological support of medical activities. The object of the study is the implemented projects on psychological support of medical workers in Russia and abroad. The article describes in detail the directions of psychological support for medical workers, as well as the concept of a Center for psychological support for resident doctors.The scientific novelty of the study lies in the fact that for the first time the realized experience of mental health practices of medical workers in Russia and abroad has been generalized, which made it possible to develop and substantiate the Concept of a Center for Psychological support of resident doctors during the period of training under residency programs. The concept of the "Center for Psychological Support of resident doctors during training" is aimed at the implementation of psychological support for students under residency programs and advanced training of heads of medical organizations in the field of personnel management and creating favorable conditions at the workplace. To achieve this goal, the Center carries out activities in four main areas: psychological and psychiatric care, methodological work, educational and scientific activities, with the involvement of the following specialists: medical psychologists, psychologists of training programs, coach, psychiatrists, researchers and methodologist.
Epistemological specificity of art: from the «psychophysiology» of the primitive world to the «practical philosophizing» of the modern era.
Authors: Demenev Denis Nikolaevich
Published: October 2023

The subject of the study is the epistemological specificity of art through the «prism» of the Paleolithic and modern eras. The focus of the research is aimed at analyzing the phenomenon of «eidetism», which is a link between modern and primitive art. The purpose of the article is to comprehend the epistemological specifics of art, which began with the «psychophysiology» of the primitive world and developed into forms of «practical philosophizing» of the modern era. The research methodology includes a review of literary sources, a dialectical approach to historical and art historical reconstruction, analysis of paleopsychological data, comparative analysis, elements of systems psychology and sociology. An element of novelty is the author's position that already in the lower, early layers of its evolution, the status of art «as one of the most ancient forms of human activity» is enriched by the status of «a form of practical philosophizing». The generalization is made that the art of the XX-XXI centuries, on the one hand, abandoned both mimesis and humanism, on the other – it continued the path of «practical philosophizing» begun in ancient times, based on the perceptual-empirical method of cognition of reality. The evolution of art from its primitive origins through archaic, classical to its modern state is, at the same time, the transformation of human consciousness, and the comprehension through artistic and creative activity of one's being and place in the universe, etc. - the development of its «depth» (the content of art). This is the development of art «in breadth» (the development of artistic form): the proliferation of its types and genres, the growth of stylistic and technological polyphony, etc. As a result, «art has come a long way from its purely psychophysiological hypostasis to «practical philosophizing». Artistic and creative activity itself as a whole continues to be the most important component of the global «mechanism» of mastering reality.
Andean civilization in Poma de Ayala’s Chronicle
Authors: Grinina Elena Anatolievna , Romanova Galina Semenovna
Published: October 2023

The subject of the analysis of this paper is the Andean civilization view by the Peruvian author of the XVI century Felipe Guaman Poma de Ayala, a Quechua Indian by origin, who became a Catholic monk, as well as a translator and mediator between two civilizations: European, personalized by Spanish administration and Catholic Church present in the conquered lands, and Andean civilization, represented by local population speaking native Quechua and other Native American languages. The collision of two worlds is clearly visible in the Chronicle «El primer nueva corónica y buen gobierno», which belongs to this author. This literary monument is an invaluable document because it describes in Medieval Spanish a disappearing world left behind, due to the lack of writing, having only artifacts of material culture and proto-hieroglyphic recording tools. The main methods of this research – analysis, synthesis, generalization. Analyzing the statements of the author of the Chronicle, who is trying to reconcile the two worlds, it is possible to recreate the panorama of the life of Andean society of that era and the sociolinguistic situation developed in it. The novelty of the study can be considered the combination of cultural and sociolinguistic approaches in the analysis of the material. The conclusion reached by the authors of the article is that the death of the Andean civilization was inevitable under the onslaught of the European one. But the Andean world, native languages and culture have not disappeared, and today are being revived, since the Peruvian society has formed a request to restore the social functions of native languages in full.
"Bullfinches of the North": children's portraits of V.A. Igoshev from the funds of the state museums of Ugra
Authors: Galyamov Artur Amirovich
Published: October 2023

The article is devoted to the theme of childhood – one of the main creative lines in the artistic heritage of Vladimir Alexandrovich Igoshev. The artistic development of the distant and previously little-known periphery began with the first graphic works and individual sketches in March 1954, dedicated to the little inhabitants of the harsh earth, and ended with heartfelt masterpieces created in the last years of the master's life, when all the strength was taken away by illness. Based on the art criticism analysis of V.A. Igoshev's works of art from the funds of the state museums of Ugra, the figurative and stylistic originality of the children's theme in the context of the "northern cycle" is revealed, the general evolution of portrait creativity is indicated. It is proved that as artistic tasks changed, as a result of deep creative immersion in the original and organic world of the North, the figurative interpretation of the children's theme, which acquires an aesthetically autonomous meaning, also changed.
Some aspects of F. Brentano's ontology and its influence on the philosophy of M. Heidegger
Authors: Gaginskii Aleksei Mikhailovich
Published: October 2023

The article examines some aspects of Brentano's ontology, starting with his 1862 dissertation "On the ambiguity of Being according to Aristotle", as well as its influence on the philosophy of M. Heidegger. The author shows that the ontology of the early Brentano is not limited to ousiology, since it includes a discussion of the field of mental being (ens rationis, ὂν ὡς ἀληθές) and it is in this aspect that he influences the young Heidegger. Following Aristotle, Brentano assigns a central role to the ontology of essence, which in the late period leads him to the position of reism, but in the lectures of the middle period Brentano discusses the problems of intentional inexistence, thanks to which projects of "new types of ontology" by Husserl and Mainong appear. The author believes that Heidegger was also influenced by these ideas. Of course, there are fundamental differences between the positions of Brentano and Heidegger, but the similarities are quite large. In particular, if Brentano, highlighting the real and true areas, gives preference in favor of the former, then Heidegger's ontology is built on the second member of this opposition. In particular, everything that can be given is called being by Heidegger, because we are talking about intentional being, about ens rationis, or ὂν ὡς ἀληθές
Melanoma Skin Cancer and Nevus Mole Classification using Intensity Value Estimation with Convolutional Neural Network
Authors: Ashafuddula N. I. Md. , Islam Rafiqul
Published: October 2023

Melanoma skin cancer is one of the most dangerous and life-threatening cancer. Exposure to ultraviolet rays may damage the skin cell's DNA, which causes melanoma skin cancer. However, it is difficult to detect and classify melanoma and nevus mole at the immature stages. In this work, an automatic deep learning system is developed based on the intensity value estimation with a convolutional neural network model (CNN) to detect and classify melanoma and nevus mole more accurately. Since intensity levels are the most distinctive features for object or region of interest identification, the high-intensity pixel values are selected from the extracted lesion images. Incorporating those high-intensity features into the CNN improves the overall performance than the state-of-the-art methods for detecting melanoma skin cancer. To evaluate the system, we used 5-fold cross-validation. Experimental results show that a superior percentage of accuracy (92.58%), Sensitivity (93.76%), Specificity (91.56%), and Precision (90.68%) are achieved.
Finding Playing Styles of Badminton Players Using Firefly Algorithm Based Clustering Algorithms
Authors: Ariyaratne Anuradha , Ilankoon I M T P K , Samarasinghe U , Silva R M
Published: October 2023

Cluster analysis can be defined as applying clustering algorithms with the goal of finding hidden patterns or groupings in a dataset. Different clustering methods provide different solutions for the same dataset. Traditional clustering algorithms are popular, but handling big data sets is beyond the ability of such methods. We propose three big data clustering methods, based on the Firefly Algorithm (FA). Three different fitness functions were defined on FA using inter cluster distance, intra cluster distance, silhouette value and Calinski-Harabasz Index. The algorithms find the most appropriate cluster centers for a given data set. The algorithms were tested with four popular synthetic data sets and later applied on two badminton data sets to identify different playing styles of players based on physical characteristics. The results specify that the firefly algorithm could generate better clustering results with high accuracy. The algorithms cluster the players to find the most suitable playing strategy for a given player where expert knowledge is needed in labeling the clusters. Comparisons with a PSO based clustering algorithm (APSO) and traditional algorithms point out that the proposed firefly variants work similarly as the APSO method and surpass the performance of traditional algorithms.
A Survey on Multi-Objective Based Parameter Optimization for Deep Learning
Authors: Chakraborty Mrittika , Pal Wreetbhas , Bandyopadhyay Sanghamitra , Maulik Ujjwal
Published: October 2023

Deep learning models form one of the most powerful machine learning models for the extraction of important features. Most of the designs of deep neural models, i.e., the initialization of parameters, are still manually tuned. Hence, obtaining a model with high performance is exceedingly time-consuming and occasionally impossible. Optimizing the parameters of the deep networks, therefore, requires improved optimization algorithms with high convergence rates. The single objective-based optimization methods generally used are mostly time-consuming and do not guarantee optimum performance in allcases. Mathematical optimization problems containing multiple objective functions that must be optimized simultaneously fall under the category of multi-objective optimization sometimes referred to as Pareto optimization. Multi-objective optimization problems form one of the alternatives yet useful options for parameter optimization. However, this domain is a bit less explored. In this survey, we focus on exploring the effectiveness of multi-objective optimization strategies for parameter optimization in conjunction with deep neural networks. The case studies used in this study focus on how the twomethods are combined to provide valuable insights into the generation of predictions and analysis in multiple applications.
On 1-absorbing Prime and 1-absorbing Primary Ideals of Amalgamations
Authors: Gündüz Abuzer
Published: October 2023

In this note, we define the 1-absorbing prime ideals and 1-absorbing primary ideals in the amalgamations of A with B along J with respect to f denoted $$A \bowtie ^f J$$ and give some results.
Padovan Numbers as Sum of Two Repdigits
Authors: Duman Merve , Keskin Refik , Hocaoğlu Leman
Published: October 2023

Padovan sequence $$(P_{n})$$ is given by $$P_{n}=P_{n-2}+P_{n-3}$$ for $$n\geq3$$ with initial condition $$(P_{0},P_{1},P_{2})=(1,1,1)$$. A positive integer is called a repdigit if all of its digits are equal. In this study, we examine the terms of the Padovan sequence, which are the sum of two repdigits. It is shown that the largest term of the Padovan sequence which can be written as a sum of two repdigits is $$P_{18}=114=111+3.$$
Advanced Thermostats for Molecular Dynamics
Authors: Tsekov Roumen
Published: October 2023

Advanced thermostats for molecular dynamics are proposed on the base of the rigorous Langevin dynamics. Because the latter accounts for the subsystem-bath interactions in detail, the bath anisotropy and nonuniformity are described via the relevant friction tensor. The developed model reflects properly the relativistic dynamics of the subsystem evolution as well as the nonlinear friction, which can occur for fast particles with large momenta at elevated temperature.
Anti-tumour Activity of Bioactive Compounds Isolated from the Hemolymph and Mucus of the Garden Snail Helix aspersa against a Panel of Human Cancer Cell Lines
Authors: Petrova Maria , Vlahova Zlatina , Schröder Maria , Tzintzarov Alexander , Velkova Lyudmila , Kaynarov Dimitar , Dolashki Aleksandar , Dolashka Pavlina , Ugrinova Iva
Published: October 2023

Cancer remains a significant global health concern, necessitating the search for new effective and safe anti-cancer agents. Natural products derived from plants and animals, including mollusks like snails, have gained attention as potential sources of novel anti-cancer compounds. Haemocyanins (Hcs), large copper-containing glycoproteins involved in oxygen transport in mollusks, have shown promise as anti-cancer agents. This study focuses on evaluating the in vitro anti-tumour efficacy of bioactive substances obtained from the hemolymph of the garden snail Helix aspersa on various human cancer cell lines representing different types of cancer. The results demonstrate that certain hemocyanin subunits from H. aspersa exhibit cytotoxic activity comparable to cisplatin, a widely used chemotherapy drug. Additional assays confirm the cytotoxic effects of the tested substances on cancer cells. The study underscores the potential of natural compounds from H. aspersa as alternative therapeutic agents for cancer treatment, while highlighting the need for further investigation. The identification of specific proteins responsible for the observed anti-proliferative effects in the mucus of H. aspersa provides insights for the development of novel cancer therapies.
Development of Integrated Fuzzy Model for Mine Management Optimization
Authors: Čelebić Miodrag , Bajić Sanja , Bajić Dragoljub , Stevanović Dejan , Torbica Duško , Malbašić Vladimir
Published: October 2023

Technoeconomic, environmental and safety criteria generally affect the management of metallic and non-metallic mining operations. The first basic question that needs to be addressed when planning ore mining is which methods are adequate and what is the optimal mining technology? Due to the complex geologic framework of ore deposits, geological exploration has rendered synonymous the inherent uncertainties, vagueness, and inaccuracies. As a result, subjective evaluation by engineers and expert experience have become increasingly important. Given that the natural language used by miners and geologists is most suited for relaying knowledge and expressing opinions, the paper tests a fuzzy optimization methodology that uses linguistic variables. Consequently, extent analysis is applied to fuzzy AHP by means of triangular fuzzy numbers to arrive at a decision about the optimal mining technology. The entire procedure constitutes an integrated mine management system, which will contribute to sustainable production in the future. A case study to which the model was applied is presented in the paper.
Optimized Feature Selection for PCOS Disease Prediction
Authors: Santhi Selvaraj , Nidhyananthan Sundaradhas
Published: October 2023

PCOS is the most predominant endocrine problem among women of reproductive age, which affects ovaries and causes irregularities in menstrual cycles, weight gain, and hirsutism [Bulsara J., P. Patel, A. Soni, S. Acharya (2021) A review: Brief insight into PCOS, Endocrine and Metabolic Sci., 3, 1–7]. The condition probably results from a mix of causes, including qualities and ecological elements. The aim of this study is to investigate the performance of Binarized Butterfly Optimization Algorithm, Binarized Grey Wolf Optimization Algorithm, Binarized Genetic Algorithm and Binarized Cuckoo Optimization Algorithm in terms of classification accuracy. Kaggle PCOS dataset is used for this work and it has 541 records and 43 attributes. The study aims to investigate the performance of four optimization algorithms in terms of classification accuracy for predicting PCOS disease. The BGWO optimization algorithm outperformed the other algorithms with 99% accuracy, while the BGA produced the most optimal subset. The study highlights the significance of feature selection in improving the performance of classification algorithms.
Neurological Soft Signs and Social Cognition in Patients with Schizophrenia: the Missing Link
Authors: Guevara Kaloyan , Kostadinov Kostadin
Published: October 2023

Schizophrenia is a debilitating mental disorder characterised by a pronounced decline in mental, physical, and social functioning. Our study aims to investigate the relationship between the socio-cognitive and the subtle motor and sensory symptoms of schizophrenia, which are, respectively, represented by facial emotion recognition deficits (FERD) and neurological soft signs (NSS). Thus, we assessed 60 patients diagnosed with schizophrenia. FERD was measured with the “Averaged Karolinska Directed Emotional Faces” set, and NSS was assessed with the Neurological Evaluation Scale. A strong and significant negative correlation was found between the NSS total score and the FERD total score (r = –0.7, p < 0.001). There was also a significant negative correlation between several of the subscores of both instruments. The results show that impaired social cognition is significantly associated with soft neurological disturbances in patients suffering from schizophrenia. Taken together, this reinforces the notion that schizophrenia is characterised by dysfunction and disconnection of a complex cerebral network, which can probably be influenced by psychosocial and physical nonpharmacological therapeutic interventions.
Dosimetric Analysis of Limiting Pelvic Bone Dose in Intensity-modulated Radiotherapy for Cervical Cancer
Authors: Qiu Hao , Liu Xin , Fang Meifang , Wu Xianxiang , Zhou Dawei , Cai Hanfei
Published: October 2023

Numerous studies have indicated the significant importance of pelvic dose in the radiotherapy process for cervical cancer patients. However, research on the actual pelvic bone dose in the treatment of cervical cancer patients using different techniques is currently relatively limited. In this study, we selected 50 postoperative cervical cancer patients. For each patient, three treatment plans with pelvic dose constraints were designed: sIMRT, VMAT, and HT. Statistical analysis was conducted on the target area and organ at risk parameters of the three groups of plans. The results indicate that all three treatment plans meet the clinical requirements. Regarding organs at risk, compared to the sIMRT and VMAT groups, the HT group showed a reduction of 11.85% and 11.07%, respectively, in V40 of bladder. Additionally, compared to the sIMRT and HT groups, the VMAT group exhibited a reduction of 14.94% and 9.53%, respectively, in V10 of pelvic bone. Furthermore, compared to the sIMRT and HT groups, the VMAT group showed a reduction of 10.76% and 6.75%, respectively, in V20 of pelvic bone, and these differences were also statistically significant (t = 21.630, t = –16.621, P < 0.05). In summary, individualized treatment design can be conducted in clinical practice based on the specific conditions of patients.
Broadband Modulation, Self‐Driven, and Self‐Cleaning Smart Photovoltaic Windows for High Efficiency Energy Saving Buildings
Authors: Na Zongxu , Liang Xiao , Wang Hao , Yu Li , Fan Chunming , Wang Qian , Wang Xianbao , Yang Huai
Published: October 2023

Smart photovoltaic windows (SPWs) are an emerging green technology presenting energy‐saving by combining solar irradiance regulation and solar energy harvesting. The SPWs integrating extraordinary energy‐saving performance, stable and controllable operational mode, and diverse functionality are essential for devising high efficiency energy‐saving buildings (ESBs). However, the attainment of such features has yet to be realized in current iterations of SPWs. Herein, a conceptual demonstration of a split‐type broadband modulation, self‐driven, and self‐cleaning SPWs is presented by coupling a silicon solar cell with a multifunctional chromogenic unit (MCU) for creating highly efficient ESBs. Within the multilayer structured MCU, thermal‐responsive polymer stabilized liquid crystal (PSLC) and VO2@SiO2 nanoparticles act as chromic component, enabling broadband light modulation. Thanks to the excellent electrothermal effect of indium tin oxide (ITO), the phase transition of PSLC and VO2@SiO2 nanoparticles can be induced by the electrical power output generated by the silicon solar cell. Therefore, the transparency of SPWs can be manipulated according to the occupant's preference during the daytime. Moreover, a superhydrophobic SiO2 coating provides SPWs with self‐cleaning capability which effectively reduces water resource consumption and eliminates the inconvenience of window cleaning, while providing occupants with a clear view even in complex weather conditions.
Engineering In Situ Catalytic Cleaning Membrane Via Prebiotic‐Chemistry‐Inspired Mineralization
Authors: Yang Xiaobin , Wen Yajie , Li Yangxue , Yan Linlin , Tang Chuyang Y. , Ma Jun , Darling Seth B. , Shao Lu
Published: October 2023

Pressure‐driven membrane separation promises a sustainable energy‐water nexus but is hindered by ubiquitous fouling. Natural systems evolved from prebiotic chemistry offer a glimpse of creative solutions. Herein, a prebiotic‐chemistry‐inspired aminomalononitrile (AMN)/Mn2+‐mediated mineralization method is reported for universally engineering a superhydrophilic hierarchical MnO2 nanocoating to endow hydrophobic polymeric membranes with exceptional catalytic cleaning ability. Green hydrogen peroxide catalytically triggered in‐situ cleaning of the mineralized membrane and enabled operando flux recovery to reach 99.8%. The mineralized membrane exhibited a 9‐fold higher recovery compared to the unmineralized membrane, which is attributed to active catalytic antifouling coupled with passive hydration antifouling. Electron density differences derived from the precursor interaction during mediated mineralization unveiled an electron‐rich bell‐like structure with an inner electron‐deficient Mn core. This work paves the way to construct multifunctional engineered materials for energy‐efficient water treatment as well as for diverse promising applications in catalysis, solar steam generation, biomedicine, and beyond.
Iontronic Textile‐based Capacitive Pressure Sensor for Unconstrained Respiration and Heartbeat Monitoring
Authors: Feng Zhiping , He Qiang , Qiu Jing , Wang Xue , Lin Yinggang , Wu Yufen , Yang Jin
Published: October 2023

Long‐term surveillance records of cardiac activity are essential for people at potential risk of cardiovascular disease. However, the existing mainstream technologies for cardiac monitoring, such as electrocardiography (ECG) and photoplethysmography (PPG), are inconvenient and prone to skin allergies due to contact measurements. Ballistocardiography (BCG) is a vibration signal related to cardiac activity, which can be monitored in an unconstrained way. Herein, an iontronic textile‐type flexible capacitive pressure sensor (i‐TFCPS) based on ionic liquid doped hollow‐porous fiber is developed to monitor physiological signals. With a high sensitivity of 7.26 kPa−1, a wide pressure range (10 Pa–600 kPa), a fast response time of 30 ms, and decent durability over 3500 cycles, the i‐TFCPS is simultaneously capable of detecting and tracking the static and dynamic changes of sitting posture, and subtle physiological information, such as respiration and BCG signals. Benefits from the iontronic textile as sensitive dielectric, the capacitive pressure sensor is able to monitor the subtle BCG signal under high static pressure in an unconstrained state, showing great potential for unobtrusive cardiac monitoring in home, office and hospital.
Anti‐Freezing Wearable Tactile Sensors Prepared by Laser Processing of Crumpled Xanthan Gum‐Based Hydrogels
Authors: Zhang Wan , Huang Yuan , Zhou Hang , Nie Zanxiang , Jin Shunyu
Published: October 2023

Wearable piezoresistive tactile sensors are becoming increasingly popular in fields related to human motion/health monitoring, and artificial intelligence. However, piezoresistive materials are still limited in terms of safety and biocompatibility in medical settings, as well as availability under harsh conditions. Herein, elastic and biocompatible hydrogels are prepared by cross‐linking of xanthan gum, polyvinyl alcohol, carbon nanotubes, and glycerol. The presence of glycerol results in hydrogel exhibiting an outstanding freezing resistance (−40 °C). Meanwhile, the controllable, large‐scale, and facile two‐step direct laser writing process allows the fabrication of hydrogels with double‐rough surface structures. By tuning surface roughness, the sensors with the resulting hydrogels show a wide detection range with high sensitivities of 27.5, 5.4, and 2.1 kPa−1 under pressures of 0.1–6, 6–25, and 25–80 kPa. The sensors also display fast response time (≈126 ms), low detection limit (2.26 Pa), good reproducibility of sensing performance (1000 cycles), relevant freezing tolerance (−40 °C), and decent environmental stability (over 30 days). This work provides a low‐cost, ease of manipulation, high reproducible, and large‐scale way for the microstructure engineering of natural‐polymer hydrogels and promotes their widespread applications.
Optimization of Core–Shell Nanoparticles Using a Combination of Machine Learning and Ising Machine
Authors: Urushihara Makoto , Karube Masaya , Yamaguchi Kenji , Tamura Ryo
Published: October 2023

Machine‐learning‐based optimization techniques are widely used for designing complex materials. However, an efficient search for the complex systems, where a combinatorial explosion occurs in the materials search space, is still challenging. Core–shell nanoparticles (CSNPs) are an example of a complex system with a high degree of freedom owing to their complicated structure and multiple constituent materials. In this study, a new black box optimization technique is developed. In this method, the structure of the CSNPs is optimized using an Ising machine and their constituent materials are selected using Bayesian optimization with the optical properties of the materials as the “descriptors”. Aiming for applications to i‐line photolithography, the authors search for CSNPs that are transparent to ultraviolet light of wavelength 355–375 nm and opaque to visible light of wavelength 400–830 nm. The transmittance spectra of the nanoparticles are obtained using a Mie theory calculator. The proposed nanoparticles with the best optical properties have a multilayered structure with a radius of approximately 40 nm and an outer shell composed of either Mg or Pb. The results indicate that a combination of various optimization techniques is more efficient in discovering the better complex materials.
Visible‐Light‐Induced Multicomponent Reaction of Aromatic Aldehydes, Amines and Sodium Difluoromethanesulfinate: Synthesis of CF2H‐Substituted Secondary Amines
Authors: Zhang Shanshan , Geng Yang , Jiao Jialong , Zou Dapeng , Wu Yangjie , Wu Yusheng
Published: October 2023

A visible‐light induced multicomponent reaction of aromatic aldehydes, amines and sodium difluoromethanesulfinate for the synthesis of fluorinated secondary amines has been investigated. The protocol affords a convenient pathway for the introduction of difluoromethyl group into imines, which generated in situ by the reaction of aldehydes and amines. A diverse range of fluorinated secondary amines were synthesized in 43%–79% yields under room temperature. In addition, a plausible mechanism was proposed based on several control experiments.
Trimetallic Oxide Electrocatalyst for Enhanced Redox Activity in Zinc–Air Batteries Evaluated by In Situ Analysis
Authors: Kumar Ramasamy Santhosh , Mannu Pandian , Prabhakaran Sampath , Nga Ta Thi Thuy , Kim Yangsoo , Kim Do Hwan , Chen Jeng‐Lung , Dong Chung‐Li , Yoo Dong Jin
Published: October 2023

Researchers are investigating innovative composite materials for renewable energy and energy storage systems. The major goals of this studies are i) to develop a low‐cost and stable trimetallic oxide catalyst and ii) to change the electrical environment of the active sites through site‐selective Mo substitution. The effect of Mo on NiCoMoO4 is elucidated using both in situ X‐ray absorption spectroscopy and X‐ray diffraction analysis. Also, density functional theory strategies show that NiCoMoO4 has extraordinary catalytic redox activity because of the high adsorption energy of the Mo atom on the active crystal plane. Further, it is demonstrated that hierarchical nanoflower structures of NiCoMoO4 on reduced graphene oxide can be employed as a powerful bifunctional electrocatalyst for oxygen reduction/evolution reactions in alkaline solutions, providing a small overpotential difference of 0.75 V. Also, Zn–air batteries based on the developed bifunctional electrocatalyst exhibit outstanding cycling stability and a high‐power density of 125.1 mW cm−2. This work encourages the use of Zn–air batteries in practical applications and provides an interesting concept for designing a bifunctional electrocatalyst.
Suppressed Water Reactivity by Zincophilic‐Hydrophobic Electrolyte Additive for Superior Aqueous Zn Metal Batteries
Authors: Wang Yahui , Zhao Ran , Liu Mingquan , Yang Jingjing , Zhang Anqi , Yue Jiasheng , Wu Chuan , Bai Ying
Published: October 2023

As one of the most promising anodes of aqueous batteries, Zn metal faces uncontrollable side reactions and deleterious dendrite growth, which drastically compromise its cycle life and Coulombic efficiency (CE). To tackle these issues, a versatile electrolyte additive is reported that can regulate the solvation structure, adsorb on the Zn surface, and in situ generate a novel zincophilic‐microhydrophobic interphase to isolate the anode from the reactive water molecules. Benefiting from its triple effects on the water reactivity modulation, the Zn metal anode exhibits excellent reversibility with an ultra‐high average CE value of 99.92% at 5 mA cm−2 in the ZnSO4 electrolyte system, and the Zn||Zn symmetric cell with ethanesulfonamide additive achieves a long lifespan over 6000 h. The merits of ESA additives are further displayed in the Zn//MnO2 full cells and Zn ion hybrid capacitors, exhibiting excellent capacity retention of 81.60% at 5 C over 1000 cycles, and a 92.25% capacity retention over 50 000 cycles at 5 A g−1, respectively. What's more, the full cells exhibit outstanding stability of 100% capacity retention after 120 cycles at 0.1 C. This strategy shows a promising alternative for the further development of aqueous Zn metal batteries with low‐cost ZnSO4‐based electrolytes.
Spatial proteomics of hippocampal subfield‐specific pathology in Alzheimer's disease and primary age‐related tauopathy
Authors: Walker Jamie M. , Orr Miranda E. , Orr Timothy C. , Thorn Emma L. , Christie Thomas D. , Yokoda Raquel T. , Vij Meenakshi , Ehrenberg Alexander J. , Marx Gabriel A. , McKenzie Andrew T. , Kauffman Justin , Selmanovic Enna , Wisniewski Thomas , Drummond Eleanor , White Charles L. , Crary John F. , Farrell Kurt , Kautz Tiffany F. , Daoud Elena V. , Richardson Timothy E.
Published: October 2023

INTRODUCTION

Alzheimer's disease (AD) and primary age‐related tauopathy (PART) both harbor 3R/4R hyperphosphorylated‐tau (p‐tau)‐positive neurofibrillary tangles (NFTs) but differ in the spatial p‐tau development in the hippocampus.

METHODS

Using Nanostring GeoMx Digital Spatial Profiling, we compared protein expression within hippocampal subregions in NFT‐bearing and non‐NFT‐bearing neurons in AD (n = 7) and PART (n = 7) subjects.

RESULTS

Proteomic measures of synaptic health were inversely correlated with the subregional p‐tau burden in AD and PART, and there were numerous differences in proteins involved in proteostasis, amyloid beta (Aβ) processing, inflammation, microglia, oxidative stress, and neuronal/synaptic health between AD and PART and between definite PART and possible PART.

DISCUSSION

These results suggest subfield‐specific proteome differences that may explain some of the differences in Aβ and p‐tau distribution and apparent pathogenicity. In addition, hippocampal neurons in possible PART may have more in common with AD than with definite PART, highlighting the importance of Aβ in the pathologic process.

Highlights

Synaptic health is inversely correlated with local p‐tau burden.

The proteome of NFT‐ and non‐NFT‐bearing neurons is influenced by the presence of Aβ in the hippocampus.

Neurons in possible PART cases share more proteomic similarities with neurons in ADNC than they do with neurons in definite PART cases.