bluuebunny/crossref_metadata_2025 huggingface dataset:
Factors influencing households’ vulnerability to desertification in rural communities of Northern Katsina, Nigeria
Authors: Yahaya Olanrewaju Yusuf , Malik Nurudeen Adesola
Published: December 2021

Rural livelihood and economic development in northern Nigeria has been characterised by the devastating effects of desertification. This paper provides an avenue to examine the peculiar factors influencing vulnerability to desertification among farm households of rural communities in desertification prone areas of Katsina State.  Data was collected from both primary and secondary sources. A systematic random sampling technique was employed to select 633 respondents in 18 rural communities from the six local government areas chosen for the study. The research instruments used were questionnaire, key informant interview and focus group discussion. Findings revealed that 93% of the respondents were from male-headed farm households, 71% were above 45 years of age and 80% have no basic primary education. Millet was the most important crop grown and 73% were full time farmers. The main perceived causes of desertification are climate change, deforestation, acts of God and environmental mismanagement. Effects of desertification were manifested in declining crop yields, loss of farmlands as well as the extinction of flora and fauna species. The factors influencing vulnerability of farm households to desertification were the ages of household heads, farming status, size of the households, access to non-farm income, migration and improved seed varieties (p < 0.05). The study, therefore, recommended the need to promote adult education, increase access to improved seed varieties and farm input, encourage livelihood diversification, intensified efforts towards effective management of environmental resources, and the involvement of vulnerable groups in the formulation and implementation of policies aimed at combating desertification.
Present-day stress field pattern in the Vrancea seismic zone (Romania) deduced from earthquake focal mechanism inversion
Authors: Andrei Bala  , Mircea Radulian  , Dragos Toma-Danila
Published: December 2021

Vrancea seismogenic zone in the South-Eastern Carpathians is characterized by localized intermediate-depth seismicity. Due to its complex geodynamics and large strain release, Vrancea represents a key element in the Carpatho-Pannonian system. Data from a recently compiled catalogue of fault plane solutions (REFMC) are inverted to evaluate stress regime in Vrancea on depth. A single predominant downdip extensive regime is obtained in all considered clusters, including the crustal layers located above the Vrancea slab. The prevalent stress regime confirms previous investigations and requires some mantle-crust coupling. The S3 principal stress is close to vertical, while S1 and S2 are horizontal, oriented perpendicularly and respectively tangentially to the Carpathians Arc bend. This configuration is present at any depth level. According to seismicity patterns, there are two main active segments in the Vrancea intermediate-depth domain, at 55 – 105 km and 105 – 180 km, both able to generate major events. The configuration of the tectonic stresses as resulted from inversion is similar in both segments. Also, high fault instability (I > 0.95) is characterizing the segments. The only notable difference is given by the friction and stress ratio parameters which drop down in the bottom segment from μ = 0.95 to μ = 0.55 and from R = 0.51 to R = 0.29. This variation is attributed to possible weakening processes activated below 100 km depth and can explain the intensification of seismicity production as earthquake rate and average energy release in the lower segment versus the upper segment.
Paleomagnetic Results from Western Anatolia: Evidence of Microblock Rotations after Emplacement of the Lower Miocene Yuntdağ Volcanic Rocks
Authors: Cengiz Mualla , Karabulut Savaş , Özçep Ferhat , Çabuk Burak Semih , Heller Friedrich
Published: December 2021

The eastern Aegean region has undergone north dipping subduction in the Oligocene, continental collision and then Miocene-Pliocene extension, which is associated with widespread Miocene volcanism. The aim of this study is to assess the possibility of block rotations due to stress variations in the Dikili (İzmir) province, Western Anatolia, based on paleomagnetic data obtained from 35 independent sites in addition to results from 19 sites in earlier studies. The lower Miocene Yuntdağ volcanic rocks were emplaced in three different structural blocks, the Dikili, Zeytindağ and Bergama blocks. Clockwise rotation is found in the Dikili and Zeytindağ blocks that varies from R (± DR) = 12.5° (± 7.4°) in the west to R (± DR) = 35.6°± (13.2°) in the east, respectively. In contrast, a counterclockwise rotation of R (± DR) =-38.1° (± 6.4°) resulted in the Bergama block, in the north of the Dikili and Zeytindağ blocks. A scissor-like basin evolution is suggested during the opening of the Bakırçay graben which led to counterclockwise rotation of the Bergama block and clockwise rotation of the Dikili and Zeytindağ blocks after lower Miocene to present. The rotation pattern derived from results of this study demonstrates that localized small scale deformation due to basin evolution besides regional affects must be considered as part of the deformation matrix in this area.
A FOTOGRAFIA COMO FONTE DE PESQUISA PARA A HISTÓRIA E MEMÓRIA DE UM MUNICÍPIO TOCANTINENSE
Authors:   Universidade Federal do Tocantins, Tocantinópolis, TO, Brasil., Alencar Larissa Barbosa , Araújo Gustavo Cunha de ,   Universidade Federal do Tocantins, Tocantinópolis, TO, Brasil.
Published: December 2021

Pesquisa sobre fotografia com o foco em um município do estado do Tocantins é um meio de tentar contar um pouco a história dessa cidade, uma vez que são poucas informações ou arquivos que revelam parte dessa história. Esta pesquisa tem como principal objetivo identificar, através de registros fotográficos, a história e a memória da cidade de Tocantinópolis - TO. De abordagem qualitativa e de natureza básica, os instrumentos de coletas de dados utilizados foram as fontes visuais (fotografias) a respeito de Tocantinópolis - TO, além da pesquisa bibliográfica. Dentre alguns resultados encontrados, as imagens analisadas revelaram parte da história e da memória dessa cidade. As informações geradas nas análises nos auxiliaram a identificar elementos visuais presentes nas fotografias que permitissem ampliar a capacidade de leitura e interpretação, o que foi fundamental para compreender as histórias, as memórias e o contexto que acompanham (ou acompanharam) essas imagens registradas nesta pesquisa.
“Start” Button Pressed. Game Studies Resumed
Authors: Afanasov Nikolai B.
Published: December 2021

Book review: Vetushinkiy, A. (2021). Gamedrome: The Things You Need to Know about Videogames and Game Culture. Moscow: Eksmo. (In Russian).
Fabula Nova Obscura Est: Possible Worlds in “Final Fantasy XIII-2”
Authors: Kirichenko Vladislav V.
Published: December 2021

Modern narratological researches are quite well developed and has long gone beyond the purely philological field. One of the applications of narratology is the study of computer games, the most relevant new medium. This paper is devoted to the issue of unusual narrative strategies used in games on the example of Final Fantasy XIII-2. The analysis is conducted via the possible-worlds method, which is currently in demand in modern humanities, but it is less known in Russia. The aim of the research is to determine the function of possible worlds existing in Final Fantasy XIII-2 for a better understanding of the game design. In the course of the work, the author examines the internal structure of the game world with the help of the theory of possible worlds, analyzes the narrative strategy, and makes a game scheme of possible worlds with accessibility links which let to see the deep internal structure of the narrative game world. In conclusion, it is clear that Final Fantasy XIII-2 contains a non-trivial narrative structure with multiple branches that is smoothed out by the gameplay and cinematic experience of the player, although such a composition of possible worlds represents a complex scheme of the game's macrocosm which demands a close attention to the narrative. The article is intended for various humanitarian specialists interested in the study of computer games.
Personal and Correspondence Discussion of International Bakhtin Theoretical and Practical Conference “Street Theatre vs. Theatre of the Military Actions”
Authors: Semenova Elena A.
Published: December 2021

This work reviews the International Bakhtin Theoretical and Practical Conference “Street theatre vs. the theatre of military actions” held in Moscow in 2019. A review of the collection of articles based on the materials of this conference is given.
The Image of the Other in the (post-)Covid Period: Analysis of Russian-language Internet Queries
Authors: Aliev Rastyam T. , Yakushenkova Olesya S.
Published: December 2021

The digital age has greatly changed the way information is stored and accessed. The Internet allows us to retrieve an unlimited amount of data from anywhere, at any time of the day or night. The search for new information consistently takes place via search engines, which process and store user query statistics. The analysis of these queries allows us to trace various social trends. At the same time, the personality of the researcher does not affect the "query" of the user, who is fully "sincere and independent" in finding the information he or she needs. Our hypothesis for this study is that by analysing the queries of Internet users we can identify the attitude of the contemporary Russian society to the Other and determine the criteria by which the image of the Other is formed. Considering the nature of the COVID-19 pandemic, the researchers assumed that periods of lockdown may have had a particular effect, increasing interest in certain markers of otherness and decreasing interest in other markers. As a result, we identified 10 models of otherness during the (post)lockdown period, in which food and sexual marker groups are the dominant ones. In particular, the Other-Chinese model, as in previous years, remains worrying. The focus has shifted from the appearance to the sexual and food aspects. The COVID-19 pandemic has played a part in this. The Other-Japanese/Korean model also remains ambiguous, but there is a downward trend in alertness. As for the other models, for the most part they are allert-neutral.
Interpretation of Sense/Meaning in the Communicative Field
Authors: Tajsin Emilia A. , Gurianov Alexei S.
Published: December 2021

The past century has shown the conversion of a so-called anthropological turn which began with works of Franz Brentano, into a linguistic turn (Richard Rorty’s term). The philosophy of language took the place of what once had been classical theory of cognition. It has become either a kind of epistemology, or analytical philosophy, or even a general theory of knowledge called in Greece, Germany and Russia gnoseology (from Greek: gnosis - knowledge).

It is necessary to make some clarifications in understanding the current intellectual situation in the field of communication theory.

Communication is a term containing a root morpheme ‘uni’ with the meaning of “one”, “unity”. For our purposes, the English word “conversation” is more suitable because, denoting a talk, it actually has the primary existential meaning of “living together”. Developing this topic, we can rely on the classic research in the field of theory and practice of communication conducted over several decades by the American specialist in the field of social psychology Deborah Tannen.
What is vocology?
Authors: Titze Ingo R.
Published: December 2021

In its broadest definition, Vocology is the study of vocalization, much like audiology is the study of hearing. Vocology includes the exploration of the full capability of human and animal sound production, some of which is embedded in human speech. For professional practice, a secondary definition of Vocology is the science and practice of voice habilitation, concept that has been in existence for more than two decades. The emphasis is on habilitation rather than re-habilitation, so that the field does not infringe on speech-language pathology. Besides, it does include the important area of animal vocalization.
Vocal tract physiology and its MRI evaluation
Authors: Murmura Bruno , Barbiera Filippo , Mecorio Francesco , Bortoluzzi Giovanni , Orefice Ilaria , Vetrano Elena , Gucciardo Alfonso Gianluca
Published: December 2021

Introduction. The rapid technological evolution in Magnetic Resonance Imaging (MRI) has recently offered a great opportunity for the analysis of voice production.
Objectives. This article is aimed to describe main physiological principles at the base of voice production (in particular of vocal tract), and an overview about literature on MRI of the vocal tract. This is presented in order to analyze both present results and future perspectives.
Method. A narrative review was performed by searching the MeSH terms “vocal tract” and “MRI” in Pub Med database. Then, the obtained studies were subsequently selected by relevancy.
Results. Main fields described in literature concern technical feasibility and optimization of MRI sequences, modifications of vocal tract in vowel or articulatory phonetics, modifications of vocal tract in singing, 3D reproduction of vocal tract and segmentation, and describing vocal tract in pathological conditions.
Conclusions. MRI is potentially the best method to study the vocal tract physiology during voice production. Most recent studies have achieved good results in representation of changes in the vocal tract during emission of vowels and singing. Further developments in MR technique are necessary to allow an equally detailed study of faster movements that participate in the articulation of speaking, which will allow fascinating perspectives in clinical use.
Reseña de Miradas de Irán. Historia y Cultura
Authors: Vardosanidze Tea
Published: December 2021

Reseña de Miradas de Irán. Historia y Cultura
The Depiction of Coconut Products (Food and Non-Food) In Tidore Islands, North Maluku
Authors: Nurhasanah Nurhasanah , Wulansari Angela , Rasulu Hamidin , Tjokrodiningrat Suryati , Fahri Johan , Suwito Suwito , Daud Nahu , Alting Husen
Published: December 2021

Indonesia is the highest producer of coconut in the world. One of the cities in Indonesia which is the central producer of coconut is Tidore Islands, North Maluku. Tidore Islands is a city in the east part of Indonesia located in the province of North Maluku. Tidore Islands has many products made of coconut tree parts as raw materials. The products are varied from food products to non-food products. This research was a descriptive study to discover the variety of coconut products produced in the Tidore Islands as basic data to develop an integrated coconut industry in the Tidore Islands. The research was conducted in 4 sub-districts that had >40 ton/year production of coconut. The result showed that black copra was the main product of coconut widely produced by people in the Tidore Islands. Other food products were white copra, coconut oil, and VCO. Non-food products widely produced by people in Tidore Island were coconut shell charcoal, coconut fiber, broomstick, and liquid smoke.
ALBINITUDE E ALBINIDADE: apresentação do dossiê
Authors: Aragão Adailton
Published: December 2021

O presente artigo tem o intuito de apresentar os trabalhos que fazem parte do dossiê e, ao mesmo tempo, refletir sobre a construção da identidade das pessoas albinas, os sentimentos e compartilhamento de suas trajetórias, estratégias e vivências, problematizando além dos fatores biológicos/médicos, discutindo a partir das Ciências Humanas, Estudos Culturais e Decoloniais. Vale destacar que todos os trabalhos têm um fio condutor que os une, ou seja, os processos identitários e os sentimentos coletivos e individuais (albinitude e albinidade) sobre ser uma pessoa albina, além de pensar como o Estado, a ciência, o mundo do trabalho, as associações, as leis, a subjetividade, a moda/publicidade e os discursos ocidentais/raciais também atuam sobre essas pessoas. Em conclusão, as pessoas albinas buscam o reconhecimento e políticas públicas para fortalecer o grupo e, assim, ter mais visibilidade na sociedade. Falar sobre identidade é pensar sobre a identidade atribuída, autoatribuída, herdada e compartilhada.
Medicion de la calidad del aire en la cuenca del lago de patzcuaro mediante el uso de un red de monitoreo perimetral
Authors: Varela Tania Paulina Pulido , Almanza Mariela De La Cruz , Yépez Félix Aldair Cázarez , Cázarez Marcial Reyes
Published: December 2021

Se pretende llevar a cabo una red de monitoreo en la cuenca del lago de Pátzcuaro con la finalidad de medir la calidad del aire tomando en cuenta los contaminantes atmosféricos presentes en suelo y agua, a causa de que en el Estado de Michoacán no se da un correcto monitoreo en cuestiones de calidad. Mediante el uso de sensores para medir los siguientes parámetros. Aire:  CO2, O3, CH4, Material Particulado. 

Suelo: Temperatura, Humedad, Conductividad eléctrica. Agua: Temperatura, Sólidos Suspendidos Totales, pH, Conductividad eléctrica. Los resultados que se pretenden obtener son tomar mediciones no solo atmosféricas sino también en áreas como el agua y el suelo, de manera que sea posible un monitoreo completo de los contaminantes, desarrollar un dispositivo autónomo en la obtención de datos atmosféricos, para llevar un control estadístico de los mismos y lograr una estación amable con la naturaleza y que no sea intimidante con la fauna, dándole un aspecto de flora nativa.
Entirely Farm-raised Snubnose Pompano (Trachinotus blochii) Under High Salinity in Saudi Arabia
Authors: Young Benjamin C. , Alfaggeh Riyadh H.
Published: December 2021

Snubnose pompano (Trachinotus blochii), a species of economic importance in the Red Sea region, has shown aquaculture potential in Saudi Arabia. The unique environment of the Red Sea causes aquaculture systems to operate under high salinity (42‰–45‰), but there is a lack of information regarding the culture of snubnose pompano in these conditions. This study estimated the survival, growth, and farming costs of snubnose pompano in two production systems: indoor and outdoor tanks. The experiments were performed in triplicate in 2020–2021, with 100 sub-adult fish per production system. The survival rate, growth performance, natural sexual maturation, and farming costs were determined. The results indicated that snubnose pompano culture is feasible under high salinity conditions using the indoor production system considering the significant differences in survival rate and growth performance, although the outdoor system had lower feed and labor costs. After 550 days of rearing, the sub-adult fish weighed more than 1,100–1,200 g, and both males and females had sexually mature gonads. These results show that spawning can be induced in high salinity (42‰) conditions. This study was the first to successfully farm-raise snubnose pompano in Saudi Arabia. Our results can thus be used as a reference for related research and aquaculture development in the Middle East region.
ON SEVERAL RECURRENT THEMES AND CONCEPTS IN SCOTTISH BALLADS
Authors: Madoyan Arpineh
Published: December 2021

The present article seeks to study the concepts of “love” and “homeland” from linguistic and cultural perspectives. Within the frames of the article an attempt is made to elucidate these concepts in Scottish ballads and media. The article also dwells upon the inherent nature of the aforementioned concepts as underlying units of Scottish culture since concepts as such reflect the mental activities of language speakers. The concepts of “love” and “homeland” embody crucial values and images common to any linguo-culture. The linguo-cultural analysis of factual data taken from folk texts (Scottish ballads) and media discourse (articles) sheds light upon not only the lexical actualization but also modern perception of the given concepts. The choice of the material is conditioned by the necessity to highlight their diachronic evolution and their importance in contemporary research. A special reference is made to the media coverage of the Scottish Independence referendum, which illustrates Scots’ attitude towards their ethnic identity and their country as a whole.
COMMUNICATING MORALITY TO AUDIENCES: SYMBOLIC INTERACTION IN FILMS
Authors: Muradian Gaiane
Published: December 2021

Through research methodology of case study the present paper promotes the connection between Symbolic Interactionism and film theory, the symbolic film world and the audience’s emotions, intellect and behavior. My purpose of focusing on the modern theory of Symbolic Interactionism is justified by the notion that the mentioned theory provides an ideal concept to achieve the objective of shaping the perceptions of massive audiences into possible positive directions, creating shared positive symbols in the society and making people react to the given symbols accordingly via film media. The analysis of the film version (A Game of Thrones) of George R. R. Martin’s series of epic fantasy novel A Song Of Ice and Fire (1996-2019) discloses the firm connection between Symbolic Interactionism and film theory, between symbolic interaction and communicating morality to audiences.
ADMINISTRATIVE-TERRITORIAL DIVISION IN THE RSFSR (1920s–1930s)
Authors: Panteleimonova Lyudmila V.
Published: December 2021

The article discusses the process of changes in the administrative-territorial division of the RSFSR in the 20s–30s of the XX century. The article distinguishes several stages. Relying on historiography and sources, the author tries to analyze and summarize the historical experience in reorganization of the RSFSR administrative-territorial system from the “spontaneous” emergence of new administrative-territorial units against the background of the existing old-regime administrative-territorial units to the first consolidation reform, when governorates, volosts, uyezds were finally liquidated, as well as the second reform of the Soviet government, the essence of which was fragmentation. The study shows that all the transformations of the young Soviet republic in the studied area took place in connection with changes in the form of power organization, as well as with a change in the principles of regional policy and the direction of economic development of the country’s territories. At the present stage, opinions on the return to the governorate administration began to appear more and more often in the research literature, which became the subject of a detailed analysis by the author of this work. The article suggests and substantiates possible directions for improving the administrative-territorial division of the RSFSR after the reform in the 1920s–1930s in order to implement the policy of the Bolsheviks and further territorial development of the country. The main approaches to the formation of the RSFSR administrative-territorial division, identification of local socio-economic systems, determination of the optimal size of administrative-territorial entities are highlighted. The interrelation between the administrative-territorial division and economic zone division in Russia is substantiated.
Comparative Analysis of the Effectiveness of Modern Endoscopic Methods of Treatment of BPH
Authors:   Urologist, Urologic Complex Clinic, O.M. Rakhmonov
Published: December 2021

Lower urinary tract symptoms caused by benign prostatic hyperplasia are the most common urological problem among men, affecting about a third of men over the age of 50 Of all surgical treatments, monopolar transurethral resection of the prostate (TURP), in which enlarged prostate tissue is resected piece by piece using a monopolar electrode, has been the standard method since the 1970s. It can significantly improve maximum flow rate (Qmax), urination-related symptoms (based on the International Prostate Symptom Assessment Scale (IPSS)), and health-related quality of life with long-term efficacy compared to medications or other minimally invasive treatments [4]. Since the 2000s, new energy systems for surgery for benign prostatic hyperplasia have rapidly become popular, including systems using bipolar energy and various laser systems such as holmium laser, potassium titanyl phosphate (KTP) laser, thulium laser and diode laser Over the past 10 years, the trend in the surgical treatment of benign prostatic hyperplasia has shifted from monopolar TURP to laser therapy and bipolar TURP. Based on the data on the effectiveness of the HoLEP technique, it becomes clear that HoLEP is ready to replace all these methods as a new standard, based on almost two decades of data that consistently demonstrate its better results and lower complication rate. This review summarizes the available literature by comparing HoLEP and traditional BPH treatments that are widely used and have long-term efficacy data. Despite the fact that there is such a wide arsenal of surgical treatment of BPH, each of these methods has its own advantages and disadvantages. This review article contains a significant portion of the best randomized data directly comparing HoLEP with alternative surgical treatments.
Renal tubular acidosis as a clinical presentation of Sjögren's syndrome: case report
Authors: Fernández Ávila D. , Vargas Caselles A. , Diz O.
Published: December 2021

We present the clinical case of a woman in the fifth decade of life, argentina, who went to the Internal Medicine emergency room of a third level hospital for symptoms of myalgia and paresis in all four extremities, acute onset, progressive, with difficulty for the mobilization of members superior, standing and walking. Severe hypokalemia, metabolic acidosis, alkaline urinary pH, positive urinary anion GAP (ammonium excretion), hypocitraturia and hypercalciuria were diagnosed. Renal Tubular Acidosis (RTA) type I was diagnosed; acute renal failure was also noted, which corrected with the treatment and elevated creatine kinase (CK). In the anamnesis, the patient reported dry syndrome associated with arthralgias of years of evolution, so that complementary studies were carried out that supported the diagnosis of Sjögren’s Syndrome (SS).
PROBLEMATIC ISSUES OF THE USE OF FIBER-OPTIC PRESSURE SENSORS IN MEDICAL PRACTICE
Authors:   Penza state University, Badeeva Elena , Murashkina Tatyana ,   Penza state University, Vasiliev Yuri ,   Kuban state medical Universit, Gerashchenko Sergey Ivanovich ,   Penza state University, Brostilova Tatiana Y. ,   Penza State University
Published: December 2021

The problematic issues that arise when measuring low pressures in medical practice, and the associated difficulties in designing measuring instruments, first of all, the low sensitivity of signal conversion, leading to an increase in the components of the basic error, the overall dimensions of the devices, the use of indirect measurement methods that entail large methodo-logical measurement errors, are considered. It is proposed to switch to advanced fiber-optic pressure sensors and new ways to measure low pressures with them.
THE EFFECT OF YB-1 PROTEIN IN СHIMERIC MODEL OF ALZHEIMER’S DISEASE
Authors:   Institute of Cell Biophysics of the RAS, Bobkova Natalia Victorovna , Poltavtseva Rimma Alekseevna ,   Institute of Cell Biophysics of the RAS, Zhdanova Daria Jurievna ,   Institute of Cell Biophysics of the RAS, Kovalev Vladimir Igorevich ,   Institute of Cell Biophysics of the RAS, Chaplygina Alina Vadimovna ,   Institute of Cell Biophysics of the RAS
Published: December 2021

The paper focuses on the molecular cell interaction of human mesenchymal stromal cells with the hippocampal primary culture of transgenic XFAD mice and the effect of multifunctional YB-1 protein on the memory and state of adult neurogenesis niches in animals with a chi-meric model of Alzheimer's disease. The results suggest the usefulness of a comprehensive use of cell therapy in combination with YB-1 to activate compensatory mechanisms in patients with Alzheimer's disease.
DEREGULATORY ACTION OF ENDOCRINE DISRUPTOR DDT ON MORPHOGENESIS AND FUNCTION OF ADRENAL ZONA GLOMERULOSA
Authors:   Research Institute of Human Morphology, Nazimova Svetlana , Yaglova Nataliya ,   Research Institute of Human Morphology, Tsomartova Dibakhan ,   Research Institute of Human Morphology, Obernikhin Sergey Stanislavovich ,   Research Institute of Human Morphology, Yaglov Valentin ,   Research Institute of Human Morphology
Published: December 2021

Exposure to endocrine disruptor DDT impairs development of adrenal zona glomerulosa by higher expression of pluripotency factors along with the suppression of factors that ensure the maturation of cortical cells. It leads to a decrease in aldosterone production and compensatory hyperplasia of zona glomerulosa.
ANTIOXIDANT PROTECTION CRITERIA IN LAPAROSCOPIC CHOLECYSTECTOMY
Authors:   PIFTPh - Branch Campus of the FSBEI, Vasilkov Valery , Safronov Alexey ,   PIFTPh - Branch Campus of the FSBEI, Osinkin Dmitriy ,   PIFTPh - Branch Campus of the FSBEI
Published: December 2021

This is article dedicated to using stabilographia for evaluation criterion system antioxidant protection after application drugs (antihypoxants – antioxydants) for prevention cognitive dysfunction in Pts after laparoscopic cholecystectomy.
Estudio de Clases y sus efectos en las conversaciones pedagógicas docentes
Authors: Gajardo Aguayo Jorge , Rojas Bravo Jorge , Albornoz Torres Catherine , Romero Inostroza Javiera
Published: December 2021

Con el propósito de contribuir a la comprensión de los procesos de conversación que se despliegan en el desarrollo de una metodología de desarrollo profesional docente; este estudio describe las modalidades de conversación que emergen en los procesos de planificación colaborativa de dos clases de lenguaje en nivel primario, en el contexto de la implementación de Estudios de Clase. A partir del análisis cualitativo de los turnos completos de palabra en los intercambios docentes y utilizando el modelo de Mercer de análisis de modalidades de conversación (1991), se observa que los docentes participantes transitan desde una modalidad disputativa y acumulativa, hacia una modalidad exploratoria, basada en la colaboración y análisis crítico.
Comparative Effect of Indole Acetic Acid and Salicylic Acid on Phytochemical Constituents and Antioxidant Potential of Three Genotypes of Tomato (Solanum lycopersicum (L.) Mill)
Authors: O.  Sowobi Olufolake , M. Esan Adewale , O. Olaiya Charles
Published: December 2021

Indole acetic acid (IAA) and salicylic acid (SA) are plant bioregulators that stimulate the desired growth and quality response in crops. This study examined the impacts of IAA or SA seed pre-treatment on phytochemical constituents and antioxidants potential in three genotypes of tomato plant. The results indicated that IAA and or SA treatments increased height of the three genotypes of tomato significantly (P ≤ 0.05) when compared with the control group. Lycopene, total flavonoid and phenolic contents of genotypes F2 cobra and panther 17 F1 treated with 40, 80, and 120 mg/L concentrations of IAA, respectively increased significantly as compared to the control group. Furthermore, IAA and or SA significantly increased H2O2 scavenging activity of F1 KIARA by 5.0% compared to the control (0.2%). Genotype F1 KIARA treated with IAA and or SA (80 and 120 mg/L) had a significant increase in DPPH scavenging activity by 55.0% and 53.0% respectively, relative to control group (11%). The Fe2+-chelating activity of IAA-treated (80 mg/L) F1 KIARA and F2 COBRA increased by 56.0% and 17.0%, respectively compared to the control. The synergistic effect of IAA and SA showed a significant effect on phytochemical constituents and antioxidant potential than individual treatment. The results showed that IAA application or in combination with SA could be used as an alternative bio-stimulant to improve the quality of tomato.
Medical Image Processing: Detection and Prediction of PCOS – A Systematic Literature Review
Authors: Pulluparambil Siji Jose , Bhat Subrahmanya
Published: December 2021

Purpose: Considered as the most common hormonal disorder among women, polycystic ovary syndrome or PCOS affects 1 in 10 reproductive aged women (18 - 44 years). Ultrasonography is applied for assessing the ovaries to detect PCOS. The patients affected by PCOS consist of 10-12 cysts present in the ovary, but more than 10 cysts are more enough to diagnose the disorder from the ultrasound images. Then, by examining the ultrasound the presence of follicles will be determined. Therefore, the image processing approaches have assisted to identify the characteristics like follicle size, number of follicles and structure to minimize the workload and time of doctors. PCOS do not have better treatment and effective diagnosis. This paper includes reviewing a summary of some of the researches that have been going in area of medical diagnosis. Based on the review, research gap, research agendas to carry out further research are identified.
Approach: A detailed study on the algorithms used in medical image processing and classification.
Findings: The study indicated that most of the classification of polycystic ovarian syndrome is done merely on the clinical data sets. The new hybrid methodology proposed will be more precise as both images and lifestyle are analysed.
Originality: The type of data required for detection system are studied and the architecture and schematic diagram of a proposed system are included.
Paper Type: Literature Review.
The Rising Tide of Women in Urology
Authors: Laguna Pilar
Published: December 2021

No abstract.
Urothelial Carcinoma Seeding at Site of Nephrostomy
Authors: Farkouh Ala'a Farkouh , Shahait Mohammed
Published: December 2021

No abstract.
Spatial Decision Support System for Efficient School Location-Allocation
Authors:   University of the Aegean, Greece, Batsaris Marios , Kavroudakis Dimitris ,   University of the Aegean, Greece, Hatjiparaskevas Euripides ,   University of the Aegean, Greece, Agouroiannis Panagiotis ,   University of the Aegean, Greece
Published: December 2021

In Greece, a lack of a planning strategy was identified in the context of allocating students to schools. Particularly, the Secondary Educational Management of Lesvos Prefecture along with school Principals decide upon student allocation based on empirical knowledge and approximation techniques. As a consequence, during the school season of 2018-2019 capacity and proximity limitations were violated. This study introduces a Spatial Decision Support System (SDSS) to assist school location-allocation decisions in future seasons. The objective of the proposed SDSS is to minimize commute-to-school distance concerning capacity and proximity limitations. For this purpose, a capacitated P-median approach is adopted and formulated as a mixed-integer linear problem. The SDSS is further evaluated using actual data for students' transition from primary to secondary education in the city of Mytilene, Greece. Evaluation of current allocation practices carried out and further compared to those obtained by the SDSS. The results indicate a decrease of 8% in total distance whereas proximity and capacity constraints were respected accordingly. The results may be potentially useful for school planners to assist the allocation decisions in the city of Mytilene.
El complejo hidrocarburífero en Mendoza
Authors: Canafoglia Eliana , Culós Verónica
Published: December 2021

Este trabajo procura definir el aporte del complejo hidrocarburífero mendocino a la matriz productiva, el empleo y los ingresos públicos e indagar sobre la dinámica de su comercialización. Estos aspectos se relacionan para caracterizarlo en sus fases de upstream y downstream, con énfasis en su composición, los actores económicos y la dinámica de su cadena productiva durante los años 2016-2019. El método de investigación es eminentemente cuantitativo, basado en datos estadísticos de diversas fuentes gubernamentales. La participación de actores públicos y privados en el complejo denota un alto involucramiento de YPF en todas las fases del proceso. En el upstream, prevalece una modalidad de asociaciones estratégicas entre actores de distinto origen (nacional/transnacional) y tamaño (única empresa/conglomerado de accionistas) y una importante participación directa en el downstream. Esto se traduce en la presencia preponderante de YPF en todo el complejo socioproductivo, con una fuerte incidencia en la dinámica de comercialización.

Palabras clave: economía regional; hidrocarburos; complejo socioproductivo;estructura del mercado
Cost-effectiveness analysis of COVID-19 vaccination in Poland
Authors: Orlewska Katarzyna , Wierzba Waldemar , Śliwczynski Andrzej
Published: December 2021

Introduction

To assess the potential value of the Comirnaty COVID-19 vaccination in Poland.

Material and methods

Markov model with 1-week cycles was used to estimate patient events, direct medical costs, utilities and cost-effectiveness for one year with and without implementing the Comirnaty vaccine in Poland. The incremental cost per quality-adjusted life-year (QALY) gained vs. no vaccine was calculated for the general population as well as for selected age-groups.

Results

In the base case analysis the incremental cost per QALY gained associated with vaccinating the whole population amounted 6,249 PLN. For individuals aged 60-69 and >80 vaccination proved to be less costly and more effective than no vaccination. The incremental cost per QALY gained when vaccinating individuals aged 40-49 and 30-39 amounted 28,135 PLN and 67,823 PLN, respectively. In the general population and in younger subpopulations the incremental cost-effectiveness ratio was most sensitive to the vaccine effectiveness, vaccine price and SARS-CoV-2 infection rates.

Conclusions

When prioritization is required due to supply constraints, vaccination of elderly is justified as it allows to achieve highest number of QALY gained and generates savings to the health care system. Continual update of the model concerning vaccine real-life effectiveness and epidemic course is required to refine the prioritisation scheme in the future.
Clinicopathologic characteristics, therapeutic modalities and survival outcomes of plasmablastic lymphoma: A real-world study
Authors: Zheng Yan-Hua , Xie Kun , Shen Hong-Yuan , Wan Zhuo , Gao Shan , Sun Wen-Rui , Gao Guang-Xun , Liu Li , Feng Juan
Published: December 2021

Introduction

Plasmablastic lymphoma(PBL)，an extremely rare subtype of B-cell non-Hodgkin lymphoma, is characterized by aggressiveness, rapid progression and bleak prognosis. Neither standardized regimen nor consensus for PBL treatment has been established.

Material and methods

We retrospectively analyzed the clinicopathologic characteristics, therapeutic modalities and survival outcomes of 418 patients registered in the Surveillance, Epidemiology, and End Results (SEER) database from 2008 to 2016 and 21 (19 treated) patients in our institution. Kaplan-Meier survival curves and log-rank test for overall survival and disease-specific survival were performed to compare each variable. Variables with statistical significance in the univariate Cox regression were incorporated into the multivariate model to determine the independent prognostic factors.

Results

In patient cohort from SEER, PBL has a striking male predilection. The median OS for all PBL patients was 17 months. The 1-year,3-year and 5-year OS rate were 54.4%, 40.4% and 37.2% respectively.Chemotherapy alone or chemotherapy combined with radiotherapy could significantly reduce the risk of death and extend the patients’ survival, yielding HR of 0.209(95%CI 0.152-0.288) and 0.187(95%CI 0.089-0.394), respectively. Radiation alone seemed useless. All patients from our institution were HIV-negative. The main therapeutic regimens were CHOP or CHOPE, DA-EPOCH, DHAP and ESHAP. Complete response was achieved in only 3 patients, while partial response in 10 patients. The median OS was 7 months. Fourteen patients later died of the disease progression.

Conclusions

Previous malignancy history, Ann Arbor stage and therapeutic modality were independent prognostic factors. Bortezomib combined with DA-EPOCH may serve as an effective regimen for PBL. The optimal therapeutic modality necessitates further exploration.
USO DA ELETROFORESE NO DIAGNÓSTICO DA ANEMIA FALCIFORME: UMA REVISÃO INTEGRATIVA
Authors: Derzi Mariane de Melo , Almeida Vivian Kelen Gonçalves de , Santos Thamires Felix dos , Cunha Júlia Gabriela Melo Carneiro da , Neta Doralice Conceição da Paz
Published: December 2021

Introdução: A anemia falciforme (AF) é uma doença hereditária que se caracteriza por uma mutação no cromossomo 11, onde há uma alteração no sexto códon da cadeia beta (β) substituindo Adenina por Timina (1). Dessa forma, ocorre a alteração na morfologia dando origem à hemoglobina S (HbS), que adquire a forma de foice em decorrência da baixa quantidade de oxigênio, ocasionando má circulação, dor, e lesões em órgãos como cérebro, pulmões e rins. A eletroforese é um dos principais métodos usados para diagnóstico dessa patologia, identificando as hemoglobinas HbA, HbF, HbC e HbS, servindo, portanto, como diagnóstico confirmatório para doença falciforme quando apresenta HbS positivo no exame. Como se trata de uma doença degenerativa, o diagnóstico precoce é fundamental para contribuir, de forma efetiva, com o planejamento e a melhoria da qualidade de vida dos pacientes (2). Objetivos: Nessa revisão, analisamos a eficiência da eletroforese, a fim de verificar sua contribuição no diagnóstico precoce da anemia falciforme. Métodos: Efetuamos uma revisão integrativa através das bases de dados Google Scholar e Scielo. Utilizando os descritores em português: “Anemia falciforme”, “Diagnóstico” e “ Eletroforese”. Foram empregados como critério de inclusão: está enquadrado nos objetivos do estudo, encontrar-se no idioma português e ser publicado entre os anos 2017-2021. No total, nove artigos atenderam aos requisitos propostos. Resultados: Foi observado que a eletroforese da hemoglobina promove a identificação das hemoglobinas presentes no sangue, avaliando com exatidão a ocorrência da anemia falciforme, sendo, então, um método de diagnóstico eficaz na identificação precoce de hemoglobinopatias. A eletroforese alcalina em acetato de celulose apresenta boa capacidade de armazenamento por longo prazo e é utilizada em exames de rotina e laboratoriais. No entanto, a eletroforese ácida em ágar apresenta melhor fragmentação da amostra do que a gerada com fracionamento de acetato de celulose. Neste método haverá a diferenciação entre hemoglobinas que migram para o mesmo local do pH alcalino, como nas hemoglobinas S, D, C e E(3). Ademais, a técnica é amplamente usada em exames laboratoriais devido seu baixo custo, auxiliando em um acompanhamento prévio da presença da doença ou do traço genético. Isso possibilita uma intervenção precoce, diminuindo a mortalidade e morbilidade da patologia, além da possibilidade de um aconselhamento genético. Conclusões: Verifica-se que o uso da eletroforese constitui um método diagnóstico eficiente, uma vez que possibilita a identificação dos tipos de hemoglobina presentes no sangue, promovendo a identificação da anemia falciforme.
ANÁLISE COMPUTACIONAL DA INTERAÇÃO ENTRE O CANAL IÔNICO DE α-HL E COMPOSTOS TIAZOLIDÍNICOS
Authors: Cavalcanti Maria Isabel dos Santos , Freitas Débora Brígida Moura de , Machado Dijanah Cota , Rodrigues Cláudio Gabriel
Published: December 2021

Introdução: Staphylococcus aureus (S. aureus) é uma bactéria associada a diversas infecções, tanto na comunidade quanto em ambiente hospitalar, ocasionando desde infecção cutânea até septicemia(1). Um importante fator de virulência é a exotoxina alfa-hemolisina (α-HL), que oligomeriza e forma canais iônicos transmembranares nas células-alvo, permitindo o fluxo livre de várias espécies químicas, resultando na morte celular(2). Diversas cepas de S. aureus exibem multirresistência aos antibióticos, limitando as opções de tratamento. Os derivados tiazolidínicos podem ser uma boa alternativa para bloquear a α-HL, pois possuem amplas propriedades bioativas, como por exemplo a antimicrobiana para cepas multirresistentes, sendo eficazes contra o S. aureus e inibindo o seu crescimento(3). Objetivos: Dada a importância da busca de compostos com ação antibacteriana, via bloqueio da α-HL, este trabalho visa analisar, via docagem molecular, a interação de derivados tiazolidínicos 5-benzilideno com o canal iônico formado pela toxina. Métodos: A estrutura cristalográfica da α-HL de S. aureus foi obtida pelo Protein Data Bank (PDB) e utilizou-se o MolView para modelagem dos compostos denominados GQ294 e GQ443, posteriormente submetidos ao Avogadro 1.1.1 para minimização de energia molecular. A docagem foi realizada pelo DockThor e os resultados foram analisados utilizando o Discovery Studio Visualizer. Resultados: A partir dos resultados de docagem pelo DockThor, foi obtida uma classificação dos compostos de acordo com suas energias totais e scores de afinidade com a toxina. Os valores de energia total do GQ443 e GQ294 foram iguais a -15,152 KJ/ mol e -19,009 KJ/ mol, respectivamente. Enquanto o score de afinidade de GQ443 e GQ294 foi de -6,820 Kcal/ mol e -5,902 Kcal/ mol respectivamente. As análises obtidas a partir do Discovery Studio Visualizer demonstraram que os dois compostos interagem com a região de constrição do canal iônico, principalmente com os resíduos GLU 111 e LYS 147, sendo estas interações mediadas principalmente por ligações de hidrogênio, além de interações do tipo cátionpi, pi-alquila, pi-enxofre. Esses dados corroboram com outros trabalhos já encontrados na literatura(4). Conclusões: Os resultados indicam, preditivamente, que os compostos GQ443 e GQ294 interagem com o canal da α-HL na região de constrição, sugerindo um bloqueio de sua atividade. São necessários dados experimentais para elucidar os dados teóricos já obtidos.