bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental Investigation on Bending Behavior of Innovative Poplar LVL Floor Diaphragms
Authors: Sun Xufeng , Wang Changyuan , Liu Yan , Ma Hongwei , Tang Shukai
Published: August 2022

Poplar laminated veneer lumber (poplar LVL) is made of fast-growing poplar veneer and structural adhesive, which owns the advantages of sustainability and stable quality. Here an innovative poplar LVL floor diaphragm is presented, mainly made up of orthogonal rib beams fitted together using L-shape steel connectors. The paper mainly deals with an experimental study on the bending behavior of the floor under transverse uniform load. Full-scale testing on eight 3.6 m × 4.8 m specimens shows that the damage phenomena of the floor mainly exhibited as the separation between the rib beams and pulling out from the rib beam for the tapping screw. Though some local damage phenomena appeared before the preset maximum loading level, the load-deflection curves basically kept linear for most of the specimens. Under the service load level of 2.5 kN/m2, the distribution of deflection and strain for the full-length rib beam substantially exhibited the characteristic of a two-way slab. In contrast, for the segmented rib beam, the situation was much more complex. Due to the parametric design of the specimens, testing results illustrated that the rib beam height played the most important role in floor stiffness. Next was the sheathing panel, while the role of segmented rib beam spacing was relatively unremarkable. At last, a revised pseudo-plate method was proposed to evaluate the maximum deflection of the novel floor, which considered the composite action by rigidity factors.
Study on the Hydration and Microstructure of B and B/Na Ion-Doped Natural Hydraulic Lime Composed with Silica Fume/Fly Ash
Authors: Zhang Yanbo , Liu Ze , Wang Jixiang , Shao Conghao , Li Jiaxing , Wang Dongmin
Published: August 2022

Natural hydraulic lime (NHL) has drawn much attention due to its environmentally friendly nature. The characteristics of both hydraulic and pneumatic components make it a potential substitute for Portland cement in surface decoration and ancient building restoration. In this study, both doping and mixing with supplementary cementitious materials were investigated. Two types of NHL3.5 were fabricated through calcination at 1200 °C with B and B/Na doping, respectively. It is noted that B ion doping is beneficial to the early compressive strength of the specimens, and B/Na doping is beneficial to the later compressive strength of the specimens. The observed outcome is that the compressive strengths of B and coupled B/Na doped NHL3.5 are higher than the blank sample due to the appearance of α’-C2S. Thereafter, the blank and doping NHL were incorporated with fly ash and silica fume. The incorporation of fly ash and silica fume could enhance the early and late hydration rate. Of the two, silica fume shows more pozzolanic effect in the early age. In the supplementary cementitious materials dosed group, pozzolanic dominates the hydration process.
Regional Renewable Energy Installation Optimization Strategies with Renewable Portfolio Standards in China
Authors: He Yuanyuan , Wan Luxin , Zhang Manli , Zhao Huijuan
Published: August 2022

In this paper, we provide theoretical and policy support for quota-allocation strategies based on a national unified renewable energy (RE) power market. Renewable portfolio standards (RPSs) are of great significance in promoting the stable development of renewable energy and improving power market decision making in China’s power industry. To resolve the geographical, resource allocation, and power-grid problems of multi-regional RE power generation, we constructed a regional distribution optimization model with the lowest cost under the RPS policy and designed a set of dynamic distribution mechanisms based on the renewable energy power quota index. The results show that it is necessary to prioritize development of wind-generated power on the North China and Northeast Power Grids, solar energy on the Northwest Power Grid, and biomass energy generation on grids in other regions to plan specific task undertakings and allocate RE power generation to each grid. We propose a multi-regional power distribution model at the lowest cost under the RPS policy to provide solutions and references for renewable energy power market quota allocation.
A New Nonlinear Controller for the Maximum Power Point Tracking of Photovoltaic Systems in Micro Grid Applications Based on Modified Anti-Disturbance Compensation
Authors: Azar Ahmad Taher , Abed Azher M. , Abdulmajeed Farah Ayad , Hameed Ibrahim A. , Kamal Nashwa Ahmad , Jawad Anwar Jaafar Mohamad , Abbas Ali Hashim , Rashed Zainab Abdulateef , Hashim Zahraa Sabah , Sahib Mouayad A. , Ibraheem Ibraheem Kasim , Thabit Rasha
Published: August 2022

In the photovoltaic system, the performance, efficiency, and generated power of the PV system are affected by changes in the environment, disturbances, and parameter variations, and this leads to a deviation from the operating maximum power point (MPP) of the PV system. Therefore, the main aim of this paper is to ensure the PV system operates at the maximum power point under the influence of exogenous disturbances and uncertainties, i.e., no matter how the irradiation, temperature, and load of the PV system change, by proposing a maximum power point tracking for the photovoltaic system (PV) based on the active disturbance rejection control (ADRC) paradigm. The proposed method provides better performance with excellent tracking for the MPP by controlling the duty cycle of the DC–DC buck converter. Moreover, comparison simulations have been performed between the proposed method and the linear ADRC (LADRC), conventional ADRC, and the improved ADRC (IADRC) to investigate the effectiveness of the proposed method. Finally, the simulation results validated the accuracy of the proposed method in tracking the desired value and disturbance/uncertainty attenuation with excellent response and minimum output performance index (OPI).
A Theoretical Study of the In Situ Structural Reconstruction of Pdn (n = 6, 19, 44) Clusters for Catalytic Hydrogen Evolution
Authors: Zhang De , Wei Guangfeng
Published: August 2022

How in situ structural reconstructions affect the hydrogen evolution reaction (HER) activity of small Pd clusters is a long-standing problem in the field of heterogeneous catalysis. Herein, we reveal the structural evolution of Pdn (n = 6, 19, 44) clusters under the HER environment via stochastic global potential energy surface searching. We theoretically demonstrated that the HER activity of Pdn clusters first increases and then decreases under long-term working conditions. The intrinsic nature of these phenomenons includes interior H formations and structural reconstructions caused by the supersaturated adsorption of H atoms. This proves that carefully adjusting the hydrogenation degree of Pd clusters is a good strategy for improving the HER’s catalytic performance.
Embolization of Large Internal Iliac Artery Pseudoaneurysm through a Retrograde Trans-Superior Gluteal Arterial Access
Authors: Ghasemi-Rad Mohammad , Vadvala Harshna V. , Lincoln Christie M. , Irani Zubin
Published: August 2022

The presence of osteal stenosis/occlusion or osteal exclusion by prior interventions poses a challenge to selective catheterization of the internal iliac artery. We describe a case where a retrograde access through the superior gluteal artery (SGA) was used to successfully treat an internal iliac artery pseudoaneurysm (PSA) in a patient when an antegrade catheterization was not feasible due to internal iliac osteal exclusion by an endograft.
Systematic Review and Meta-Analysis on Knowledge Attitude and Practices on African Animal Trypanocide Resistance
Authors: Kasozi Keneth Iceland , MacLeod Ewan Thomas , Waiswa Charles , Mahero Michael , Ntulume Ibrahim , Welburn Susan Christina
Published: August 2022

Background: African trypanocide resistance is an emerging public health emergency whose control requires a revisit on farmer’s knowledge, attitudes, and practices in developing countries. African animal trypanocide resistance (AATr) is rife in an environment where drug use and policy decisions are disjointed. The objective of the study was to identify community factors responsible for the development of AATr. This was important since diminazene aceturate (DA), isometamidium chloride (ISM), and homidium bromide (HB) have existed for over 30 years and no new drugs have been provided to farmers. Methods: An electronic keyword search across 12 databases was conducted using a search criterion from 1806 to June 2022. This generated a total of 24 publications, but after removing duplicates, review articles, and nonrelated articles, a total of eight papers were included in the analysis by following the PRISMA checklist. A meta-analysis was conducted on the data extracted and the risk ratio and inverse variance at 95% confidence interval were calculated using RevMan®. Results: All the eight articles in the study showed that DA was the most preferred trypanocide in both West and Eastern Africa. Poor farmer knowledge of AATr and limited drug options were major drivers for trypanocide resistance. In addition, farmer treatments, use of untrained personnel, poor administration, poor dosing, and preparation of trypanocides were major drivers for the development of AATr and similarities were identified in DA and ISM practices (P = 0.13). Conclusions: AATr is spread in developing countries due to a lack of community knowledge, attitudes, and drug-use practices. This situation could be reversed through interdisciplinary collaborations in endemic communities by promoting effective treatments and responsible drug handling.
The First Two Cases of Monkeypox Infection in MSM in Bahia, Brazil, and Viral Sequencing
Authors: Brites Carlos , Deminco Felice , Sá Marcia Sampaio , Brito Jean Tadeu , Luz Estela , Stocker Andreas
Published: August 2022

Monkeypox infection is rapidly spreading across the world. Despite the increasing number of cases, only a few reports have been published, and most are on people living without HIV. We report here the first two cases of monkeypox infection in Bahia, Brazil, one of them in a person living with HIV, on stable treatment. Both cases had a similar evolution, with a limited number of lesions and mild symptoms, with a complete recovery after 7–10 days. The potential route of transmission was via oral sex for the first case and was undefined for the second one. Both cases were confirmed through detection of the viral genome by PCR, and the partial sequence of the first case indicates the infection was caused by the West African clade. These cases confirm that monkeypox infection is currently being transmitted in Brazil and that people living with HIV on stable treatment are not likely to present a more severe form of monkeypox.
A Single Oral Immunization with Replication-Competent Adenovirus-Vectored Vaccine Induces a Neutralizing Antibody Response in Mice against Canine Distemper Virus
Authors: Du Xiang , Goffin Emeline , Gillard Lucie , Machiels Bénédicte , Gillet Laurent
Published: August 2022

Canine Distemper Virus (CDV) is a fatal and highly contagious pathogen of multiple carnivores. While injectable vaccines are very effective in protecting domestic animals, their use in the wild is unrealistic. Alternative vaccines are therefore needed. Adenovirus (AdV) vectors are popular vaccine vectors due to their capacity to elicit potent humoral and cellular immune responses against the antigens they carry. In parallel, vaccines based on live human AdV-4 and -7 have been used in U.S. army for several decades as replicative oral vaccines against respiratory infection with the same viruses. Based on these observations, the use of oral administration of replication competent AdV-vectored vaccines has emerged as a promising tool especially for wildlife vaccination. Developing this type of vaccine is not easy, however, given the high host specificity of AdVs and their very low replication in non-target species. To overcome this problem, the feasibility of this approach was tested using mouse adenovirus 1 (MAV-1) in mice as vaccine vectors. First, different vaccine vectors expressing the entire or part H or F proteins of CDV were constructed. These different strains were then used as oral vaccines in BALB/c mice and the immune response to CDV was evaluated. Only the strain expressing the full length CDV H protein generated a detectable and neutralizing immune response to CDV. Secondly, using this strain, we were able to show that although this type of vaccine is sensitive to pre-existing immunity to the vector, a second oral administration of the same vaccine is able to boost the immune response against CDV. Overall, this study demonstrates the feasibility of using replicating AdVs as oral vaccine vectors to immunize against CDV in wildlife carnivores.
Therapeutic Potential of 5′-Methylschweinfurthin G in Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma
Authors: Koubek Emily J. , Weissenrieder Jillian S. , Ortiz Luz E. , Nwogu Nnenna , Pham Alexander M. , Weissenkampen J. Dylan , Reed Jessie L. , Neighbors Jeffrey D. , Hohl Raymond J. , Kwun Hyun Jin
Published: August 2022

Merkel cell carcinoma (MCC) is a rare but aggressive form of skin cancer predominantly caused by the human Merkel cell polyomavirus (MCPyV). Treatment for MCC includes excision and radiotherapy of local disease, and chemotherapy or immunotherapy for metastatic disease. The schweinfurthin family of natural compounds previously displayed potent and selective growth inhibitory activity against the NCI-60 panel of human-derived cancer cell lines. Here, we investigated the impact of schweinfurthin on human MCC cell lines. Treatment with the schweinfurthin analog, 5′-methylschweinfurth G (MeSG also known as TTI-3114), impaired metabolic activity through induction of an apoptotic pathway. MeSG also selectively inhibited PI3K/AKT and MAPK/ERK pathways in the MCPyV-positive MCC cell line, MS-1. Interestingly, expression of the MCPyV small T (sT) oncogene selectively sensitizes mouse embryonic fibroblasts to MeSG. These results suggest that the schweinfurthin family of compounds display promising potential as a novel therapeutic option for virus-induced MCCs.
Connect to Protect: Dynamics and Genetic Connections of Highly Pathogenic Avian Influenza Outbreaks in Poultry from 2016 to 2021 in Germany
Authors: King Jacqueline , Staubach Christoph , Lüder Christiane , Koethe Susanne , Günther Anne , Stacker Lina , Rubbenstroth Dennis , Dietze Klaas , Grund Christian , Conraths Franz J. , Harder Timm , Beer Martin , Pohlmann Anne
Published: August 2022

During autumn/winter in 2016–2017 and 2020–2021, highly pathogenic avian influenza viruses (HPAIV) caused severe outbreaks in Germany and Europe. Multiple clade 2.3.4.4b H5 HPAI subtypes were responsible for increased mortality in wild birds and high mortality and massive losses in the poultry sector. To clarify putative entry sources and delineate interconnections between outbreaks in poultry holdings and wild birds, we applied whole-genome sequencing and phylodynamic analyses combined with the results of epidemiological outbreak investigations. Varying outbreak dynamics of the distinct reassortants allowed for the identification of individual, putatively wild bird-mediated entries into backyard holdings, several clusters comprising poultry holdings, local virus circulation for several weeks, direct farm-to-farm transmission and potential reassortment within a turkey holding with subsequent spill-over of the novel reassorted virus into the wild bird population. Whole-genome sequencing allowed for a unique high-resolution molecular epidemiology analysis of HPAIV H5Nx outbreaks and is recommended to be used as a standard tool. The presented detailed account of the genetic, temporal, and geographical characteristics of the recent German HPAI H5Nx situation emphasizes the role of poultry holdings as an important source of novel genetic variants and reassortants.
HSP27 Attenuates cGAS-Mediated IFN-β Signaling through Ubiquitination of cGAS and Promotes PRV Infection
Authors: Li Xiangrong , Xie Jingying , Li Dianyu , Li Hongshan , Niu Yuhui , Wu Bei , Yang Yanmei , Yan Zhenfang , Zhang Xiangbo , Chen Lei , Feng Ruofei
Published: August 2022

Pseudorabies (PR) is a domestic and wild animal infectious disease caused by the pseudorabies virus (PRV) and is one of the major infectious diseases that endanger the global swine industry. Studies have reported that PRV may achieve cross-species transmission from pigs to humans in recent years. Therefore, in-depth exploration of the relationship between PRV and host proteins is of great significance for elucidating the pathogenic mechanism of PRV and anti-PRV infection. Here, we report that heat shock protein 27 (HSP27) ubiquitinates and degrades cyclic GMP-AMP synthase (cGAS) and attenuates cGAS-mediated antiviral responses, thereby promoting PRV infection. Overexpression of HSP27 promoted PRV proliferation in vitro, while knockdown of HSP27 inhibited PRV infection. Importantly, we found that HSP27 inhibited PRV infection or poly(dA:dT)-activated IFN-β expression. Further studies found that HSP27 may inhibit cGAS-STING-mediated IFN-β expression through targeting cGAS. In addition, we found that HSP27 can suppress the expression of endogenous cGAS in different cells at both gene transcription and protein expression levels, and that HSP27 interacts with and ubiquitinates cGAS. In conclusion, we reveal for the first time that HSP27 is a novel negative regulator of the cGAS-STING signaling pathway induced by PRV infection or poly(dA:dT) activation and demonstrate that HSP27 plays a crucial role in PRV infection.
Genomic Analysis of Porcine Reproductive and Respiratory Syndrome Virus 1 Revealed Extensive Recombination and Potential Introduction Events in China
Authors: Yu Fang , Liu Liqiang , Tian Xiaoxiao , Chen Ligong , Huang Xinyi , Sun Yue , Yan Yi , Tian Zhijun , Cai Xuehui , Liu Di , An Tongqing
Published: August 2022

Porcine reproductive and respiratory syndrome (PRRS), caused by the PRRS virus (PRRSV), is considered one of the most devastating swine diseases worldwide. PRRSV-1 was first isolated in China in 2006. However, there were few reports concerning the genetic characteristics of PRRSV-1 in China. In this study, three PRRSV-1 strains (HL85, HeB3, and HeB47) were detected by a general RT-qPCR method from clinical samples in 2018. HeB47 was identified as a recombinant between the BJEU06-1 and CReSA228-like strains. To further analyze the recombination and deletion features of PRRSV-1, all the available 88 complete genome sequences (isolated in 19 countries) from 1991 to 2018 in GenBank were analyzed. The high-frequency recombination regions were concentrated in NSP2 and GP2 to GP4. More importantly, phylogenetic analysis of PRRSV-1 revealed four independent introductions in China. Therefore, it is necessary to strengthen the important monitoring of breeding pigs and pork products and epidemiological surveys on pig farms to prevent the further spread of PRRSV-1.
Healthcare in Malta
Authors:   Blood Transfusion Department, Kremenskaya Central District Hospital, Frolova E. V.
Published: August 2022

Malta is an island state located in the Mediterranean Sea and a former British colony. Malta gained independence only in 1964, and 10 years later received the status of a parliamentary republic. The population of Malta is a little over 440 thousand people, and the country has the status of the most sparsely populated EU member state. Every fifth Maltese living on the island is an emigrant; the emigration of pensioners from the UK is especially popular here. Life expectancy for men in Malta is 79.6 years, for women 84.3 years. The state guarantees the provision of medical care for all segments of the population. The annual expenditure on health needs exceeds 10%; the financing of the medical sector is carried out through taxes and weekly insurance premiums, which are paid by both employers and employees themselves. To obtain medical ser vices, one can apply to both public and private healthcare institutions. In order to receive medical care foreigners who are not EU citizens have to purchase a private health insurance policy. Malta is a popular destination for medical tourism, as the quality of provided medical services meets European standards, while prices are about a third lower than in European countries.
The role of variant anatomy of the inferior mesenteric artery in segmental colon resections with lymphodissection in patients with colorectal cancer
Authors:   Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenov University), Seurko K. I. , Vinоkurоv I. A. ,   Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenov University), Kasymov M. U. ,   Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenov University)
Published: August 2022

During laparoscopic surgery for colorectal cancer, vascular structures may be incorrectly identified and damaged due to ignorance of the variant anatomy of the inferior mesenteric artery (IMA), lack of tactile sensations, narrowed field of vision, which leads to complications such as massive bleeding and intestinal ischemia. Therefore, the preoperative study of the variant anatomy of the IMA is of paramount importance. Knowing the variant anatomy of the vessels before surgery, you can make an operation plan in advance, which will ensure fast and safe vascular ligation at the required level and lymph node dissection. Aim: To develop a classification of IMA variability for practical use in operations for colorectal cancer. Material and methods: From February 2013 to March 2022, 214 computed tomograms (CT) of abdominal organs with intravenous contrast were analyzed. We studied the variant anatomy of the IMA. Results: We proposed the classification of structure of the IMA and its branches. This is especially important when the safe lymph node dissection along the IMA is necessary. I type — several colonic branches derivate from the IMA by independent trunks (54,2 %); II type — all colon branches derivate from the IMA in one point like a “goose paw” (25,2 %); III type — one colon branch departs from the IMA by a single trunk; then it divides into colonic branches (20,6 %). The frequency of coincidence of intraoperative data with preoperative CT data was 95.8 %. The sensitivity of the method is 95.8 %, the specificity of the method is 100%. Conclusion: CT with 3D vascular reconstruction allows the surgeon to perform extended lymph node dissection in colorectal cancer with minimal risk of complications.
Surgical antibiotic prophylaxis: current issues of beta-lactams use
Authors:   Federal State Autonomous Educational Institution of Higher Education «Peoples'Friendship University of Russia», Zyryanov S. K. ,   State Budgetary Healthcare Institution «City Clinical Hospital No. 24 of the Moscow Healthcare Department», Butranova O. I. ,   Federal State Autonomous Educational Institution of Higher Education «Peoples'Friendship University of Russia»
Published: August 2022

The most common prescriptions for antibiotics in surgery are in the area of surgical antibiotic prophylaxis. According to clinical guidelines, beta-lactams, in particular, first and second generation cephalosporins, and in some cases aminopenicillins, should be used as drugs of choice. These drugs are leaders with regards to assessing the contribution of drugs of various pharmacological groups to the formation of drug allergies. However, real clinical practice reveals fewer cases of true allergy to beta-lactams compared to self-reported data by patients. Both underestimation and overestimation of the risks of hypersensitivity reactions with cephalosporins and penicillins is critical to the ultimate outcome of patient management. This review includes the main characteristics of drugs used for antibiotic prophylaxis in surgery and highlights topical issues of beta-lactam allergy and management of patients with various types of hypersensitivity reactions.
Uso de producciones audiovisuales para fomentar el turismo. Caso: “Ecuador el país de los 4 mundos”
Authors: Villena Álvarez Dean Tadeo
Published: August 2022

El propósito de este artículo es analizar las ofertas turísticas del sector audiovisual como como estrategia publicitaria para incentivar el turismo de masas. Se pretenden destacar el gentilicio de personas dentro de las ciudades turísticas a través de imágenes, atractivos y paisajes exóticos de los cuales se sabía a través de fotografías y relatos en Ecuador; siendo así considerado como una nueva técnica de marketing turístico alejado de los medios convencionales y así atraer una mayor afluencia de turistas a un destino. Para establecer el vínculo entre el turismo y el sector audiovisual, para ello, se llevó a cabo un análisis de la campaña “All you need is Ecuador” creada en abril del 2014. Se realizó un estudio exploratorio bajo el paradigma cualitativa para obtener una respuesta a la estrategia de posicionamiento de Ecuador. Se concluye que a pesar de que la campaña All You Need en Ecuador fue un proyecto que no tuvo continuidad en los años, los indicadores demuestran que en el futuro se pueda volver a invertir en esta campaña producto de los resultados obtenidos.
Calidad del servicio en los mercados, supermercados y bodegas de la ciudad de Arequipa
Authors: Vargas Espinoza Luis , Rodríguez Martínez Anaelvira Jimena , Espinoza Riega Jorge David
Published: August 2022

El objetivo de la investigación es conocer tomando en cuentas las percepciones de los niveles de satisfacción que tienen los jóvenes de los mercados, supermercados y bodegas para luego contrastar ese resultado con las expectativas y establecer la calidad del servicio, para ello se ha creado un cuestionario de tres dimensiones: merchandising visual, mix de marketing y el post compra. Los jóvenes prefieren primero los supermercados, luego las bodegas y en tercer lugar a los mercados de abastos. Los promedios de satisfacción por dimensión a nivel general quien ofrece un mejor servicio de calidad son los supermercados donde el 86.26% reciben lo que estaban esperando, en un segundo lugar están las bodegas ya que el 71.73% de los clientes perciben que han recibido lo que esperaban y finalmente se encuentran los mercados donde el 64.85% perciben que reciben lo que esperaban cuando compran en dichos establecimientos.
Prevalencia de la fatiga en cáncer infantil e interferencia en las actividades de la vida cotidiana
Authors: Abril Mera Tania , Noblecilla Troya Joselyne , Hernández Salazar Angie , Méndez Pérez Boris , Correa Cum Dennisse Solange
Published: August 2022

La fatiga es una complicación que afecta a los pacientes con cáncer infantil aproximadamente al 65%. Objetivo. Analizar la prevalencia de la fatiga en niños y adolescentes con cáncer y su interferencia en las actividades de la vida cotidiana. Materiales y Métodos. El enfoque de la investigación es cuantitativo, con alcance descriptivo, en base a las variables fatiga, edad, sexo y tipo de cáncer, posee un diseño no experimental y los instrumentos que fueron utilizados son historia clínica, base de datos e inventario breve de la fatiga. Muestra: Son 104 pacientes de 5 a 18 años de edad. Resultados. De los 104 pacientes, 58 son del género masculino y 46 del género femenino. La fatiga asociada a otras complicaciones, 94 dieron positivo para la fatiga y 10 negativos, de los cuales el 40% presento fatiga con atrofia muscular (42 pacientes), el 35% fatiga con trastornos motores (36 pacientes), el 15% fatiga con trastornos posturales (16 pacientes) y el 10% sin fatiga. En la prueba de los 6 minutos, se determinó que el 10,6% del total de la muestra pasaron la prueba, mientras que la diferencia del (89,4%) no pasó. Conclusión. La fatiga interfiere en las actividades de la vida cotidiana y es muy común en pacientes con leucemia con predomino al sexo masculino y la edad promedio es de 5 a 10 años.
Calidad de vida y salud en pueblos indígenas amazónicos durante la pandemia COVID-1
Authors: Maraza Vilcanqui Beker , Maraza Vilcanqui Nain , Flores Choque Gladys Martha , Maraza Vilcanqui Queke
Published: August 2022

La investigación tuvo como propósito comprender la calidad de vida y salud de las familias pertenecientes a los pueblos  indígenas de la amazonia peruana en tiempos de COVID-19. Es una investigación cualitativa con diseño descriptivo  fenomenológico, la población en estudio son 47 pueblos indígenas y se tomó muestra a las 16 estudiantes que imparte la  educación superior en la Universidad Nacional Intercultural de la Amazonía, el muestreo fue no probabilístico intencional.  La técnica para la recolección de datos que ayudó recoger la experiencia vivida es la observación y entrevista, siendo los  instrumentos la guía de entrevista y guía de observación para obtener resultados sobre la experiencia vivida en tiempos de  pandemia, como resultado la mayor preocupación fue la calidad de vida y la salud sana en la población amazónica, más  resalta recuerdos negativos sobre posible contagio, vivir con Covid-19, e incierto sobre post pandemia. En conclusión, la  mayoría de personas han experimentado los rezagos de pandemia al contagiarse, porque, generó dolor corporal, miedo,  sentimientos bajos, tristeza, soledad, desmotivación, traumas psicológicos, distanciamiento social, contracción de otras  enfermedades y muchos cambios en la vida personal y familiar.
Satisfacción con la vida y Conductas de salud en estudiantes universitarios de nuevo ingreso
Authors: Guerrero Alcedo Jesús Manuel , Palacios Garay Jessica Paola , Espina Romero Lorena del Carmen , Marimon Lambertinez Libia Esther , Jaimes Alvarez Freddy Roberpierre
Published: August 2022

En la actualidad resultan escasos los estudios que relacionen la satisfacción con la vida y las conductas saludables en estudiantes que inician sus estudios universitarios, aun cuando se sabe que la transición a la etapa universitaria puede originar diversos cambios con repercusiones importantes para la salud de los estudiantes. Objetivo. Determinar la relación entre la satisfacción con la vida y las conductas de salud en estudiantes de primer semestre de una universidad pública venezolana. Método. Estudio de naturaleza cuantitativa, no experimental, descriptivo, correlacional y transversal, utilizó una muestra conformada por 636 estudiantes (65% mujeres y 35% hombres) con edades entre los 15 y 27 años, seleccionados bajo un muestreo no probabilístico intencional. Resultados. Los estudiantes se caracterizan por estar satisfechos con su vida y presentan niveles moderados de conductas saludables en general. Asimismo, la satisfacción con la vida difiere según el sexo y el estrato socioeconómico, mientras que algunas conductas de salud difieren según el sexo, el estrato socioeconómico y la edad. Por otra parte, la satisfacción con la vida presenta relación significativa con las conductas de salud a nivel general y en las dimensiones conductas preventivas, sueño, actividad física, control en el consumo de drogas y chequeo médico. Conclusión. La satisfacción con la vida resulta ser una variable protectora que fomenta conductas saludables en estudiantes universitarios, en especial los que recién inician los estudios, siendo importante considerarla en futuras intervenciones y programas de promoción de la salud.
Percepción cultural del embarazo, parto y puerperio en las comunidades de los Andes peruano
Authors: Maquera Maquera Yuselino , Calderón Torres Alfredo , Maquera Maquera Yolynda , Zuñiga Vasquez María Emma , Vásquez Pauca Mario José
Published: August 2022

Desde hace varios años, en diferentes países se viene manifestando la necesidad de retomar el embarazo, parto y puerperio como un proceso “humanizante”, para ello se habla de la desmedicalización bajo el enfoque de volver a lo natural. Una práctica por los pobladores, pero estos conocimientos están siendo desplazados a causa de la globalización. Objetivo. Revaloración las costumbres y creencias del embarazo, parto y puerperio de las madres acerca de este hecho tienen mayor confianza en el uso de la medicina tradicional con plantas, animales, minerales y objetos astronómicos en los tratamientos terapéuticos en el cuidado del niño. Materiales y métodos. fue inductivo de enfoque cualitativo, diseño etnográfico-descriptivo, el muestreo no probabilístico-por expertos. En el procedimiento de investigación se logró interpretar las opiniones, percepciones culturales, actitudes y expectativas de las informantes clave y fue procesado mediante el software Atlas ti. Resultados. Se determinó que la revaloración está relacionado con las costumbres y creencias de la alimentación del proceso del embarazo, parto y puerperio vinculados con deidades en la tradición cultural. La función de las parteras, es determinante para el tratamiento terapéutico con el uso de plantas, minerales y animales. En este proceso es muy importante las practicas rituales en el proceso del embarazo, parto y puerperio que se realiza en base a la tradición cultural ancestral en las comunidades del ande peruano. Conclusión. Los recursos de la terapia tradicional y de la atención primaria de la salud de las parteras son útiles y benéficas para los cuidados perinatales.
Infección del tracto urinario por enterobacterias en pacientes del laboratorio “San José”- Azogues
Authors: Guaraca Siguencia Ligia Alexandra , Carchipulla Sanango Claudia Jeaneth , Ortiz Tejedor Jonnathan Gerardo
Published: August 2022

La infección del tracto urinario es un proceso inflamatorio de los órganos involucrados, ocasionados por diferentes tipos de microorganismos, especialmente enterobacterias. Objetivo. El propósito del presente artículo es conocer la frecuencia de ITU con respecto a género, edad y de ello la presencia bacteriana y su perfil de resistencia en pacientes que acuden al laboratorio “San José” de la ciudad de Azogues-Ecuador. Materiales y Métodos. se aplicó un estudio de tipo descriptivo de corte transversal, documental - secundario; en pacientes de ambos sexos y diferentes rangos de edad. La muestra final de aislados positivos fue de 210 pacientes, los datos obtenidos fueron procesados en el Software SPSS versión 25.0 para su tabulación y análisis. Resultados. Se determinó un mayor porcentaje de aislados positivos en mujeres con 93,7 %. El grupo etario con más afección es la adultez con un 50,5 %, seguido de adultos mayores y jóvenes con un 21,4 % y el 11 % respectivamente. El agente etiológico con mayor incidencia fue Escherichia Coli con un 70,95 % con una resistencia a SXT el porcentaje restante corresponde a Providencia spp, Klebsiella spp, Enterobacter spp y Proteus spp. La opción terapéutica para las enterobacterias fue fosfomicina, amoxicilina + clavulánico y nitrofurantoína. Conclusión. El estudio viabilizó la obtención de resultados reales al respecto del ITU, confirmado la presencia de Escherichia coli como agente etiológico principal siendo su prevalencia en mujeres.
Pengaruh Store Atmosphere dan Price Discount terhadap Impulsive Buying pada Butik Fyllo Closet di Kota Pematangsiantar
Authors: Harahap Mei Sarah , Siregar Dahrul
Published: August 2022

This study aims to determine the effect of store atmosphere and price discounts on impulse buying at the Fyllo Closet Boutique in Pematangsiantar City. This research is a type of descriptive research using a quantitative approach. The sampling technique used purposive sampling method and how to determine the sample size using the slovin method with a total sample of 110 respondents. The data collection technique used an online questionnaire through a google form which had been tested for validity and reliability. Data analysis technique using multiple linear regression. The results showed that: (1) Store Atmosphere had a positive and significant effect on Impulse Buying. (2) Price discount has a positive and significant effect on Impulse Buying. (3) Store Atmosphere and Price Discount have a positive and significant impact on Impulse Buying.
Sustainable Tourism for the Green Economy
Authors: Letunovska Nataliia , Kwilinski Aleksy , Dzwigol Henryk , Lyulyov Oleksii , Pimonenko Tetyana
Published: August 2022

The paper analyses the innovative direction of sustainable tourism in Poland. It is investigated by means of a marketing survey of the respondents from this country and neighbouring regions. The authors’ findings deal with the results in the framework of the green economy. The research hypothesis is to check the target group’s awareness of post-industrial tourism in the field of region's rehabilitation, readiness to support sustainable development goals in their areas and to determine the most effective marketing tools to promote sustainable tourism. The authors found that local authorities play an essential role in developing territories through implementing healthy regional strategies. Among the insights of the research is the concept of Smart City as a promising tool for promoting healthy types of activity, to the respondents' opinion. Regions are defined as local centres where sustainable tourism principles could be implemented to reduce consequences unwelcome for the environment and economy.
The Prospects of Retail Payment Developments in the Metaverse
Authors: Melnychenko Oleksandr
Published: August 2022

In the age of technological development, rapid technological progress, and the metaverse development in which humans interact with each other and with the environment using virtual real-world metaphors, payment systems may also need to be re-considered. The study aims to find an answer to the question of what should be retail payments in the metaverse and to begin interdisciplinary discussions about their implementation in this environment. The author reviews the literature which shows that i) socio-economic relations are being implemented in the metaverse, but they still require the money to participate in the exchange relationships, as well as to support such a system; ii) it is impossible to abandon all forms of physical exchange, which is the basis of modern society; iii) the metaverse is an environment usually of anonymous users, who do not have the right to make significant purchases without their identification; iv) accounting of transactions remains the basis of payments in the metaverse as well.
A Review of the Monograph by Yu.M. Kharazishvili “Systemic Security of Sustainable Development: Evaluation Tools, Reserves and Strategic Implementation Scenarios”
Authors: Kwilinski Aleksy
Published: August 2022

The monograph proposes a modern concept of sustainable development from the standpoint of security, which contains a general systematic idea of ways to move from the current position of the object of management to the desired. The necessity to adhere to the limits of safe existence of dynamic economic systems, which connects the problem of sustainable development with the problem of security, is substantiated. The presented concept is based on the methodology of identification and strategy of sustainable development from the standpoint of security and adaptive methods of regulation of management theory for the scientific justification of strategic planning in the medium and long term. It is proposed to take into account the shadow indicators in the components of sustainable development to reveal the adequacy of the real state of the economy using the developed method of its assessment and de-shadowing. The violation of the generality of macroeconomic identity of GDP by the end-use method at the regional level is proved and on this basis the method of determining the shadow net export due to violations at customs and in interregional movement of goods and services is proposed. Possibilities of application of the stated approaches at different levels of economic activity are shown. The dual role of the shadow economy is revealed: as obstacles to sustainable development and as a significant reserve for modernization and growth of Ukraine's economy.
XIV Congreso Colombiano de Fitoquímica
Authors: Marquez Vizcaíno Rita Luz
Published: August 2022

Desde la bella ciudad de Sincelejo, Sucre, Colombia, el comité organizador del XIV Congreso Colombiano de Fitoquímica y I Congreso de Semilleros en Fitoquímica de educación media, realizados en modalidad híbrida, presencial y remota...
Actividad citotóxica in vitro del aceite esencial de Lippia origanoides y su efecto antibacteriano frente a cinco bacterias de importancia clínica.
Authors: Quiguanás-Guarín Edwin Stiven , Bedoya Agudelo Juan Pablo , López-Carvajal Jhon Esteban , Ramírez Tabares Yuly Andrea , Padilla Sanabria Leonardo , Castaño-Osorio Jhon Carlos
Published: August 2022

Los aceites esenciales son metabolitos secundarios obtenidos a partir de plantas aromáticas, cuyos componentes provocan un considerable efecto antibacteriano.
Difusión in vitro de liposomas cargados con curcumina y aceite esencial de Lippia origanoides, en una celda de Franz
Authors: López-Carvajal Jhon Esteban , Bedoya Agudelo Juan Pablo , Padilla Sanabria Leonardo , Castaño-Osorio Jhon Carlos
Published: August 2022

Las celdas de Franz son un instrumento utilizado para evaluar la difusión dérmica y determinar la cinética de liberación de moléculas biológicamente activas como los liposomas, los cuales son vesículas compuestas de fosfolípidos, que han sido empleadas como sistemas de liberación de fármacos.
Evaluación de un humedal artificial plantado con Thalia geniculata para la biorremediación del Arroyo Grande de la Sabana, Departamento de Sucre – Colombia
Authors: MIELES Jorge , VERGARA Vicente
Published: August 2022

Las aguas residuales constituyen un problema ambiental al ser vertidas en las fuentes hídricas sin ser tratadas. El Arroyo Grande de la Sabana, en Sucre, Colombia, recibe aguas residuales de los municipios de Sincelejo, Morroa, Corozal, Betulia, Sincé y Galeras, de los cuales solo Sincelejo cuenta con una planta de tratamiento de aguas residuales (PTAR), estas aguas llegan al arroyo con altas concentraciones de contaminantes.
Fraccionamiento biodirigido de Oxandra longipetala (Annonaceae) usando ensayos antifúngicos in vitro
Authors: PELÁEZ HERNÁNDEZ Carolina , LOBO ECHEVERRI Tatiana
Published: August 2022

Se estima que los hongos fitopatógenos causan alrededor del 70% de las enfermedades que afectan los cultivos1. Anualmente, estos organismos son responsables de hasta la mitad de las pérdidas de la producción de alimentos a nivel mundial2...
Actividad leishmanicida del extracto etanólico de Annona purpurea Moc. & Sessé ex Duna en aislado clínico de Leishmania braziliensis, agente causal de leishmaniasis cutánea en Los Montes de María, Sucre, Colombia
Authors: ZULUAGA QUINTERO Claudia Patricia , GARCÍA NOVOA Diana Lucia , MARTINEZ ABAD Lily Paola , CAMACHO BURGOS Erwin Yesid , PAREJO ALCOCER Maria Stella , CONTRERAS CASTILLO Osnaider José , MARQUEZ VIZCAINO Rita Luz , BEJARANO MARTINEZ Eduar Elías
Published: August 2022

La leishmaniasis, es una enfermedad parasitaria considerada un problema de salud pública a nivel mundial, responsable de altos índices de mortalidad y morbilidad. Los tratamientos que se emplean presentan serios problemas asociados a su toxicidad y efectos secundarios severos...
Constituyentes químicos de Piper pertomentellum atenúan la producción de virulencia del patógeno Pseudomonas aeruginosa in vitro
Authors: Hernández-Moreno Lida V , Pabón-Baquero Ludy C , Patiño-Ladino Oscar J
Published: August 2022

Pseudomonas aeruginosa es una bacteria de prioridad critica según la OMS y está asociada a una amplia gama de infecciones principalmente en la unidad de cuidados intensivos (UCI).
Estudio químico de partes aéreas de Piper cumanense y evaluación de la inhibición de biofilm en Pseudomonas aeruginosa multiresistente.
Authors: SILVA-CARRERO Diego A. , HERNÁNDEZ-MORENO Lida V. , PABÓN-BAQUERO Ludy C. , PRIETO-RODRÍGUEZ Juliet A. , PATIÑO-LADINO Oscar J.
Published: August 2022

La Organización Mundial para Salud y la Organización Panamericana de Salud han rendido informes sobre la resistencia a los antimicrobianos (RAM), planteando a Pseudomonas aeruginosa como un patógeno de prioridad critica, el cual está relacionado con infecciones nosocomiales que prolongan los tiempos de estadía de los pacientes en UCI...
Constituyentes aislados de Piper ceanothifolium con potencial aplicación para el control de hongos fitopatógenos asociados al cultivo de cacao
Authors: Mahecha-Jimenez Yudy S , Prieto-Rodríguez Juliet A , Ladino-Vargas Cristobal , Patiño-Ladino Oscar J
Published: August 2022

El cacao es uno de los productos agrícolas de mayor proyección socioeconómica en el país. Sin embargo, los rendimientos en su producción han disminuido, debido a diversos factores, destacándose la proliferación de enfermedades asociadas a hongos fitopatógenos.
Oxigenación de los fenoles presente en los extractos totales de hoja y corteza seca de Vismia baccifera (L.) Planch ＆Trian.
Authors: Ortiz Cristian C , Atencio Sixta I , Castillo Osnaider , Parejo María S , Márquez Rita L
Published: August 2022

Las plantas pertenecientes al género Vismia son usadas tradicionalmente en heridas, herpes, hongos, afecciones del tracto urinario, enfermedades superficiales de la piel y como purgante; a su vez poseen varias bioactividades como antibacteriano, antimicóticos, antiparasitarios, insecticidas y antivirales.
Jugos de frutas tropicales inhiben la carbonilación proteica in vitro
Authors: Marrugo-Padilla Albeiro , De la Rosa-Cogollo Isaac , Méndez-Rodríguez María , Rodríguez-Cavallo Erika , Méndez-Cuadro Darío
Published: August 2022

La carbonilación de proteínas es una modificación oxidativa covalente e irreversible capaz de inducir cambios estructurales en éstas y afectar su plegamiento e interacción con otras biomoléculas.
Estudio metabolómico preliminar de Espeletia grandiflora Humb. & Bonpl. (Compositae) a lo largo de un gradiente altitudinal y fenológico del Parque Nacional Natural Chingaza.
Authors: Rojas-Bautista Felipe , Jácome Jorge , M. Costa Geison , Téllez Nohemí , Gil Elizabeth
Published: August 2022

Los frailejones (subtribu: Espeletiinae), son un exitoso grupo de plantas pertenecientes a la familia Asteraceae que han logrado adaptarse a las condiciones altamente dinámicas y heterogéneas del páramo.
Evaluación antimicrobiana del crudo alcaloidal de la especie vegetal Ipomoea carnea sobre enterobacterias
Authors: ESCOBAR POVEDA Juan Camilo , CASTAÑEDA-GÓMEZ Jhon Fredy
Published: August 2022

En la especie Ipomoea carnea se han identificado siete alcaloides, entre los cuales se encuentra, la swainsonina y las calisteginas B1, B2, B3 y C1, como los responsables de la intoxicación en el ganado, comprobado por medio de tejidos hepáticos, pancreáticos, renales y neuronales.
Evaluación del potencial bioherbicida de especies arbóreas colectadas en remanentes de bosques andinos
Authors: ORTIZ LOPEZ Juan José , LOBO ECHEVERRI Tatiana
Published: August 2022

Siendo Colombia un país mega-diverso, sus especies nativas han sido poco exploradas, como fuente alterna de compuestos bioactivos, que ayuden a mitigar problemáticas causadas por productos sintéticos.
Ojo de poeta (Thunbergia alata): Estudio preliminar de su potencial químico y antifúngico.
Authors: VANEGAS Miguel Ángel , BRAVO Chaucanés Claudia , Modesti COSTA Geison
Published: August 2022

Thunbergia alata (ojo de poeta) es una especie vegetal originaria del este de África. Se encuentra ampliamente cultivada en regiones tropicales del mundo, considerándose como una especie de alto riesgo de invasión en algunos países, incluyendo Colombia.
Determinación de polifenoles totales, flavonoides y evaluación antimicrobiana en tres ecotipos de Moringa oleifera cultivadas en Cuba.
Authors: Lago Abascal Vivian , Echemendia Arana Olga , Gonzales García Kethia L. , Hernández Rivero Yasnay , Valdés Iglesias Olga , Gutiérrez Cuesta Richard , Almora Hernández Ernesto , Monteagudo Borges Raisa , Bolaños Queral Graciela , Díaz Novo Liliam
Published: August 2022

Moringa oleifera Lam, se considera uno de los árboles más útiles y con múltiples beneficios. Sus hojas acumulan altos contenidos de compuestos a los que se le atribuyen propiedades biológicas.