bluuebunny/crossref_metadata_2025 huggingface dataset:
Hepatocellular carcinoma metastasis to the mandible
Authors: Mastrofrancisco Rosana , Marcucci Marcelo , Costa Anderson Costa Lino , Palma Luiz Felipe
Published: October 2023

Introduction: Metastasis of hepatocellular carcinoma (HCC) to the mandible is an extre-mely rare condition with less than a hundred cases reported worldwide. Such lesions do not have any pathognomonic clinical, radiologic, or histologic features, and they can mimic many other conditions or diseases with orofacial involvement. Case report: We present an interesting but intriguing case of metastasis of HCC to the mandible, which presented as an orofacial swelling accompanied by intense pain and spontaneous bleeding following tooth removal. Conclusion: This paper highlights the importance of integration of the in-depth medical history of the patient, clinical findings, and microscopic examinations in cases of uncommon oral lesions of challenging diagnosis.
Diffusion weighted imaging and apparent diffusion coefficient discrimination of odontogenic keratocyst
Authors: Pinto Antonione Santos Bezerra , Sousa André Luca Araújo de , Falcão Carlos Alberto Monteiro , Ferraz Maria Ângela Arêa Leão , Gomes João Pedro Perez , Lopes Sérgio Lúcio P. de Castro , Silva Paulo Henrique Braz da , Costa André Luiz Ferreira , Cardoso Luana Leal Cosmo
Published: October 2023

Radiological diagnosis of Odontogenic Keratocyst (OKC) is particularly challenging due to its radiological similarities in comparison to other odontogenic lesions. This study aimed to provide data from the literature review and to present a case report in which the diffusion-weighted imaging (DWI) and the apparent diffusion coefficient (ADC) using magnetic resonance imaging (MRI) were obtained to establish a possible way to differentiate OKC from other odontogenic lesions. Literature review data and its association with the present case report shows the potential to use DWI and ADC combination as a possible tool to differentiate OKC from ameloblastomas.
Miejsce jazzu w polskiej edukacji muzycznej w latach 1960‑1990. Postawy, deklaracje, fakty
Authors: Niźnik Krzysztof
Published: October 2023

The article outlines the place of jazz in Polish musical culture, highlighting that it is chiefly shaped by the unfavorable stance of the precursors of Polish post-war musicology toward this genre. The materials presented in the text reveal a prevailing negative disposition among the Polish musicological community towards jazz, or even a lack of competence for its appropriate analysis. Such an outlook appears to adversely impact not only the status of music education in Poland but also the general level of artistic and aesthetic sensibility in contemporary Polish society.
Composing and recording Autumn Tales: thoughts on the creative process of finding a new trio sound
Authors: Dorůžka David ,   Conservatory of Jaroslav Ježek in Prague
Published: October 2023

Artykuł Davida Dorůžki opisuje wyzwania związane z komponowaniem na trio w składzie gitara, bas i perkusja w kontekście współczesnego jazzu. Autor opisuje swoje doświadczenia w obcowaniu z zespołem tego typu, jego historię i możliwości. Oferuje on także wgląd w proces kompozycyjny, który poprzedził nagranie w 2016 roku albumu Autumn Tales z Jiřím Slavíkiem i Martinem Novákiem. Analizuje również kilka utworów znajdujących się na płycie, omawia swoje muzyczne wpływy i pisze o różnych źródłach inspiracji, które doprowadziły do powstania tego albumu.
Learning by ear: the tradition of learning music aurally and its practical use in gospel choir rehearsals and workshops
Authors: Fentress Brian
Published: October 2023

Artykuł prezentuje cele i zalety nauki ze słuchu; to w jaki sposób ta metoda przyniosła korzyści czarnym chórom kościelnym i wspólnotowym w przeszłości i obecnie, a także to, jak wieloletnia edukacja muzyczna wśród osób czarnoskórych wpłynęła na sposób nauczania i uczenia się muzyki. Jest również próbą odpowiedzi na pytanie, czy istnieją praktyczne metody dyrygowania chórami gospel, które mogą być stosowane zarówno przez formalnie wykształconych i niewykształconych dyrygentów chórów. W drugiej części tekstu autor prezentuje autorską metodę dyrygowania. Większość informacji zawartych w tym artykule pochodzi z pracy doktorskiej autora artykułu pt. Gospel Music Repertoire as Material for Artistic Activity in Conducting.
50 lat Warsztatów Muzycznych w Chodzieży. Wspomnienia uczestników
Authors: Szrom Janusz
Published: October 2023

The Jazz Workshops “Cho-Jazz” in Chodzież earned extraordinary reputation in the musical environment for years. Organized since 1971 as the first summer jazz school in Europe, today it is most likely the only such cultural event in the world, which has been continuously educating young jazz adepts for over 50 years. It is here that the first tools of jazz education were developed, which are now used by the most prominent representatives of Polish jazz education. Over the decades, Chodzież has become a revered summer jazz school, and the well-versed educational staff is also unrivaled in their ability to build a close relationship between student and master.
Rozwój języka wykonawczego flecistów w muzyce jazzowej od roku 1913 do współczesności
Authors: Wiśniowski Leszek
Published: October 2023

The article presents the development of the performance language of jazz flutists from 1913 to the present day. It contains the sources of inspiration as well as the meaning of mutual influences. It reveals the role of classical and avant-garde music in shaping the style of some jazz flutists. It appeals to the biographical facts, indicates the motives for which the described jazzmen took up the flute. It also talks about those musicians whose flute activity is not known to the wider audience. The work mainly describes artists from the USA but also, albeit to a lesser extent, applies to those who work in Asia, Europe, including Poland. To clarify data, the described historical period was divided into decades.
Dyrygent – lider zespołu rozrywkowego w muzycznym ruchu amatorskim
Authors: Piotrowski Ryszard J.
Published: October 2023

The article is trying to define what is potential, predispositions, and qualities of a modern conductor. A conductor is also, in fact, a leader, educator and instructor in a conducted ensemble, operating in the community within the amateur art movement. Every good band leader faces certain challenges. The paper also defines the qualities that musicians should have and what conditions they should meet in ensemble musicianship. It also indicates measures that should be taken in order to create universal music education and learning to play instruments, and then in ensemble musicianship. This is because ensemble playing is an essential element for proper functioning in the musical world. The paper shows examples of the activities of ensemble musicianship and its benefits.
Synthesis and characterization of carboxymethyl cellulose from pine needles for biomedical and regenerative medicine applications
Authors: Bhadri N. , Bhatt P. , Barthwal A. , Phulara S. Ch.
Published: October 2023

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Carboxymethyl cellulose (CMC) is one of the most widely used components of hydrogel for biomedical applications as its precursor cellulose is the most abundant biological macromolecule on the Earth. Recent years have seen a remarkable increase in CMC synthesis from various plant sources. In the present study we have utilised cheer pine needles (Pinus spp.) due to its abundance and easy availability in Himalayan regions across India. The cellulose was extracted from pine needles. Then, the etherification process was used to prepare CMC from pine needle cellulose, with sodium hydroxide and monochloroacetic acid (MCA). CMC yield, degree of substitution, water retention capacity, oil retention capacity, ash content, and CMC content were determined by comparing obtained CMC to standard CMC. The purity of the synthesised CMC is represented by CMC content. The prepared CMC had a purity of 10 % and a yield of 110 %. The degree of substitution, water retention capacity, and oil retention capacity were all determined to be 0.02, 8.4 g/g, and 4g/g, respectively. The ash content of the synthesised CMC was calculated to be 6 %. The majority of characteristics were either equivalent to commercial CMC or superior to it therefore the synthesised product can be used as a potential component to fabricate biomaterials for biomedical applications.
Conducting Needs Assessments to Inform Instructional Design Practices and Decisions
Authors: Stefaniak Jill
Published: October 2023

The purpose of a needs assessment is to determine the current state of performance and the desired state of performance. When conducting a needs assessment, it is important to gather sufficient data to understand the situation warranting instructional solutions. The purpose of this chapter is to provide guidance for instructional designers interested in conducting needs assessment practices on a variety of scales.
THE APPLICATION OF DRILL PLAY METHOD ON RECEPTIVE LANGUAGE DISORDER OF CHILDREN WITH DOWN SYNDROME
Authors: Yulidar  , Anneta Talya Vida Tobing  , Fildza Khalisha  , Lisna Az Zahra Taufik
Published: October 2023

Down syndrome is a chromosomal abnormality that occurs during the prenatal period. This condition causes a child to experience several disorders, one of which is receptive language disorder or understanding. This receptive language disorder can occur due to short-term memory impairment. Seeing this, an intervention is needed to optimise the receptive language skills of children with Down syndrome. Purpose: This study aims to determine the effectiveness of the application of the drill play method in improving the receptive language skills of children with Down syndrome. Method: using a single subject experiment, using a one group pretest-posttest design. The research subject was a girl with Down syndrome aged two years and three months and had receptive language disorder. Data collection was done through interviews with the client's parents, direct observation of the client, tests, and document studies. Speech therapy was conducted for 10 meetings with the drill play method which emphasises repetition of exercises for client's receptive language understanding. Perceptual assessment by comparing word-level receptive language skills before and after therapy. Results: There was no improvement in word-level receptive language skills. Conclusion: the application of the drill play method in receptive disorders of children with down syndrome has not increased due to the lack of therapy sessions conducted and the provision of material that is less familiar to the client's daily life. Suggestion: further research needs to be done on how effective the frequency of therapy in children with down syndrome using the drill play therapy method so that it can be used as a reference for speech therapists in determining the number of therapy meetings.
IVENTARISASI ENDOPARSIT PADA IKAN LAYUR (Trichiurus lepturus) DI PASAR SAIK KUALA PEMBUANG
Authors: Herlina Sri , Agus Emelina
Published: October 2023

Penelitian ini bertujuan untuk megiventarisasi jenis endoparasit yang infeksi pada ikan layur (T. lepturus) di Pasar Saik Kuala Pembuang. Ikan layur (T. lepturus) yang diteliti sebanyak 30 ikan dan diidentifikasi di Laboratorium Program Studi Budidaya Ikan, Politeknik Seruyan. Parasit yang diamati yaitu endoparasit. Data hasil penelitian dianalisis dengan menghitung perbedaan prevalensi dan perhitungan secara deskriptif untuk mengetahui tingkat infeksi pada berbagai organ. Hasil penelitian menunjukan bahwa prevalensi infeksi parasit pada ikan layur (T. lepturus) yang dipasarkan di Pasar Saik Kuala Pembunag termasuk dalam kategori ‘selalu’ dengan nilai sebesar 93,2%. Menurut William dan Bunkley (1996), kategori ‘selalu’ ini menggambarkan bahwa parasit menginfeksi ikan sebesar 90- 98 %.
Transgenic animal production: present scenario-a review
Authors: M. C. M Zakeel, , Marikar Faiz M. M. T.
Published: October 2023

The advent of DNA recombinant technology and the possibility of gene transfer between organisms have opened a wide range of possibilities for improvement of livestock production and human health care products. The recent advances in gene transfer, animal cloning, and assisted reproductive techniques have partly fulfilled the expectation in the field of livestock transgenesis. This paper reviews the recent advances and applications of transgenesis in livestock and their derivative products. Typical agricultural applications include improved carcass composition, wool production, and lactation performance which is enhanced disease resistance and reduced environmental impact. Transgenic farm animals have also become important in human medicine as sources of biologically active proteins, as donors in xenotransplantation, for research in cell and gene therapy and for human disease. modeling. Until recently, pronuclear microinjection of deoxyribonucleic acid (DNA) was the standard method for producing transgenic animals. This technique is now being replaced by more efficient protocols based on somatic nuclear transfer that also permit targeted genetic modifications. Lentiviral vectors and small interfering ribonucleic acid technology are also becoming important tools for transgenesis.
Samonaprawiający się robot - quasi - transakcyjność robota RPA
Authors: Kajrunajtys Agnieszka , Kajrunajtys Danuta
Published: October 2023

Przedmiotem rozważań są wnioski z realizacji rozszerzenia funkcjonalności oprogramowania narzędziowego Wizlink® o przełomowe rozwiązanie adresujące problem „broken bot syndrome”. Wraz ze wzrostem praktycznego użycia w organizacjach robotów RPA automatyzujących czynności pracowników w interakcji z aplikacjami ujawniły się problemy, których skali nie dało się przewidzieć przed wdrożeniem automatyzacji. Jednym z nich jest rozważany niniejszym problem z nie kończeniem przez robota RPA całego zbioru czynności przewidzianych w jego scenariuszu. Rozwiązaniem tego problemu było opracowanie i zaimplementowanie innowacyjnych mechanizmów quasi-transakcyjności robota. Rozwiązanie wzorowane jest na monitorach transakcji (CICS, Tuxedo) i modelu transakcyjności ACID. Dzięki temu w znakomitej większości robot jest w stanie automatycznie ponowić wykonanie przerwanej transakcji lub ją wycofać. Robot odwołujący się do ekranów aplikacji biznesowych nie ma jednak takiej swobody działania jak systemy zarządzania bazą danych. Stąd opracowany mechanizm określono mianem quasi-transakcyjnym, bo nie jest rozwiązaniem w pełni uniwersalnym.
ChatGPT en el ámbito educativo
Authors: Berrones Yaulema Laura Pilar , Buenaño Barreno Pamela Nataly
Published: October 2023

La creciente inmersión de la Inteligencia Artificial (IA) en las actividades cotidianas, incluida la educación, responde a su capacidad para transformar y mejorar diversos aspectos de la vida. La IA ofrece soluciones eficientes y personalizadas, optimiza procesos y facilita el acceso a información y recursos. En el ámbito educativo, su presencia es especialmente significativa, porque revoluciona la forma en que se aprende y enseña. Conocer el uso de estas herramientas en los procesos educativos es esencial para comprender su potencial y limitaciones. Esta investigación identifica las capacidades y limitaciones de la herramienta de IA ChatGPT y su aplicación en el ámbito educativo, información que permite aprovechar sus beneficios al máximo, diseñar estrategias pedagógicas efectivas y éticas, además de abordar los desafíos que surgen al integrar la IA en la educación. La investigación es de tipo documental y se apoya en la revisión bibliográfica. Entre los resultados se presenta que las capacidades del ChatGPT tienen un gran potencial educativo al interactuar en lenguaje natural y generar respuestas coherentes. Su versatilidad en estilos y lenguajes agiliza respuestas a preguntas complejas y el acceso a materiales variados. No obstante, puede carecer de precisión y dar respuestas inapropiadas debido a la falta de contexto y conocimiento ético. La generación de información incorrecta y la ausencia de empatía son desafíos, aunque puede mejorar el diseño curricular, personalizar el aprendizaje y actuar como tutor virtual. Aun así, se deben abordar estas limitaciones para asegurar una implementación educativa efectiva y ética.
ENGINE PERFORMANCE TEST EVALUATION OF BIODIESEL BLENDS FROM CASTOR SEED OIL AT VARYING MIXTURE RATIOS AND ENGINE SPEED
Authors:   Ahmadu Bello University, Zaria, Manu Ibrahim Dominic
Published: October 2023

The growing global demand for energy with expected fossil fuel shortages stresses the search for alternative energy sources. Moreover, the high fossil energy consumption with its adverse impact on environment and climate changes calls for cleaner fuels. One of the most alternative fuel sources is the extraction of biofuels from Castor oil by acid-based catalysed trans- esterification process. In this study, experimental analysis was carried out to produce biodiesel from castor oil using trans- esterification process. The trans- esterification process occurs between castor oil and methanol in the presence of potassium hydroxide (KOH) as a catalyst. The biodiesel fuel produced was varied at different mixture ratios with diesel. The high viscosity and acid value of the castor oil was further reduced by two-three stage trans-esterification process to within the American Society for Testing and Materials (ASTM) D6751 – 0.2 limits for biodiesel. The biodiesel was tested in a single cylinder diesel engine and results of gas emission, load analysis, fuel consumption rate and engine efficiency were all obtained which are close to those of diesel fuel thus confirming that it can be used as alternative fuel for diesel engines. The Brake thermal efficiency was 96% at B-20 biodiesel blend which is close to the conventional diesel engine efficiency of 95.5%.
ญาณวิทยาต้านอาณานิคม และทฤษฎีความสัมพันธ์ระหว่างประเทศ ของไทยในอนาคต
Authors: ศุภชลาศัย ชญาน์ทัต
Published: October 2023

บทความนำเสนอญาณวิทยาต้านอาณานิคมที่ได้รับพัฒนาการทางความคิดมาจากกลุ่มนักคิดลาตินอเมริกันเพื่อเป็นบทเรียนให้กับการพัฒนาทฤษฎีความสัมพันธ์ระหว่างประเทศของไทยในอนาคต โดยเริ่มต้นจากการแสดงให้เห็นถึงข้อจำกัดของทฤษฎีหลังอาณานิคม และโต้แย้งว่าทฤษฎีหลังอาณานิคมไม่สามารถเชื่อมโยงนัยยะทางความคิดเข้ากับสรรพสิ่งต่างๆ ที่เผชิญกับความทรมาน ทั้งที่เป็นมนุษย์และไม่ใช่มนุษย์ ทฤษฎีหลังอาณานิคมไม่อาจเป็นเครื่องมือที่ก่อให้เกิดการสร้างทฤษฎีความสัมพันธ์ระหว่างประเทศของประเทศที่ไม่ใช่ตะวันตกรวมถึงของไทย บทความจึงหันเหไปสู่ญาณวิทยาแบบโลก‘พหุภพ’ ตามที่รามอน โกรสโฟเกล เรียกว่าเป็น ‘การหันเหสู่การต้านอาณานิคม’ นอกจากนี้ วอลเตอร์ มิกโนโลนักคิดผู้วิจารณ์ปรัชญาตะวันตก ได้สร้างคำเฉพาะหรือมโนทัศน์ของตนเองเพื่อเป็นการต่อต้านญาณวิทยาแบบตะวันตก นักคิดกลุ่มลาตินอเมริกันกลุ่มนี้มอบบทเรียนสำคัญแก่นักวิชาการความสัมพันธ์ระหว่างประเทศของไทย ผู้ปรารถนาได้รับการตระหนักในเชิงทฤษฎีและญาณวิทยาภายในสาขาวิชาความสัมพันธ์ระหว่างประเทศ
ที่พรมแดนระหว่างอนุภูมิภาคเอเชียใต้และอาเซียน : มองอินเดียเชื่อมต่อเมียนมาร์ เพื่อ “มุ่งหน้าไปด้วยกัน
Authors: คำวัง อภิรัฐ
Published: October 2023

จากความร่วมมือระหว่างอาเซียน-อินเดีย และจากกระบวนการพัฒนาประเทศภายในอินเดีย ได้ผลักดันให้อินเดียเร่งรัดพัฒนาพื้นที่ชายแดนภาคตะวันออกเฉียงเหนือ โดยเฉพาะพรมแดนอินเดีย-เมียนมาร์ เพื่อเชื่อมต่อทางกายภาพสู่อาเซียนด้วยทางหลวงไตรภาคี อินเดีย-เมียนมาร์-ไทย การพัฒนาดังกล่าวเป็นที่มาของการศึกษาวิจัยเชิงคุณภาพทางด้านสังคมศาสตร์ครั้งนี้ ซึ่งให้ความสนใจต่อพรมแดนระหว่างสองภูมิภาค จึงได้ค้นคว้าข้อมูลพื้นฐานด้านสังคมและเศรษฐกิจตามแนวพรมแดน โดยศึกษาเอกสารและศึกษาภาคสนามที่พรมแดนของอินเดีย ทำให้ทราบถึงสภาพความเป็นจริงที่ตลาดพรมแดนและความก้าวหน้า โดยที่อินเดียเตรียมจะเปิดประตูสู่อาเซียนที่รัฐมณีปุระ ส่วนพรมแดนแห่งอื่นคงเปิดพื้นที่เฉพาะพ่อค้าท้องถิ่นกลุ่มชาติพันธุ์ ยังไม่ยกระดับเป็นพรมแดนนานาชาติ จึงเป็นประเด็นที่จะต้องมีการตกลงระหว่างอินเดียกับเมียนมาร์เพื่อนำไปสู่ผลสำเร็จของการเชื่อมต่อดังกล่าว ทั้งนี้ ผลการศึกษาคาดหวังว่าจะช่วยส่งเสริมความรู้ความเข้าใจเกี่ยวกับความสัมพันธ์ระหว่างอาเซียนกับอินเดียมากยิ่งขึ้น รวมทั้งเป็นประโยชน์ต่อการเตรียมความพร้อมของไทยก่อนการเปิดทางหลวงไตรภาคี
การปกครองตามธรรมชาติ: กฎเหล็กสามข้อของการปกครองแบบผสม
Authors: ไชยภูมี เอกลักษณ์
Published: October 2023

บทความชิ้นนี้นำเสนอกรอบแนวคิดเรื่องการปกครองตามธรรมชาติในฐานะที่เป็นฐานคิดของทฤษฎีการปกครองแบบผสมผ่านสิ่งที่เรียกว่า “กฎเหล็กของการปกครองแบบผสม” ที่เกิดขึ้นจากเงื่อนไขเฉพาะและธรรมชาติที่แตกต่างกันขององค์ประกอบภายในการปกครองแบบผสม อันประกอบด้วย  (1) กฎเหล็กของมหาชน (2) กฎเหล็กของกลุ่มคน และ (3) กฎเหล็กของเอกบุคคล โดยกฎเหล็กประการแรกเกี่ยวข้องกับกลไกสร้างความชอบธรรมให้แก่ระบอบการเมืองต่าง ๆ  ในขณะที่กฎเหล็กข้อที่สองเกี่ยวข้องกับส่วนที่เป็นกลไกการทำงานจริงของระบอบการเมืองที่จำเป็นต้องอาศัยคนจำนวนน้อยในการปฏิบัติหน้าที่เฉพาะและเพื่อให้การบังคับใช้กฎเกณฑ์ต่าง ๆ ของรัฐบาลดำเนินต่อไปได้  กฎเหล็กประการสุดท้ายอาจพิจารณาผ่านปรากฏการณ์ที่เรียกว่า   “การผงาดของรัฐบาลโดยคนคนเดียว” ในยุคโลกาภิวัตน์ ซึ่งเป็นอีกเงื่อนไขหนึ่งที่ทำให้ระบอบการเมืองทุกระบอบต้องมีกลไกที่คอยเติมเต็มช่องว่างในการใช้อำนาจบริหารของรัฐสมัยใหม่ และรวมถึงอำนาจในสภาวะฉุกเฉินอย่างทันท่วงทีที่ปรากฏในรูปของผู้เผด็จการตามรัฐธรรมนูญ
ประวัติศาสตร์และการเมืองของ “พวกขี้แพ้”: การครอบงำ อำนาจ และการต่อต้าน ในทัศนะของเจมส์ ซี สก็อตต์
Authors: พัวพันสวัสดิ์ กรพินธุ์
Published: October 2023

บทความชิ้นนี้มุ่งสำรวจความคิดทางการเมืองของเจมส์ ซี สก็อตต์ ผ่านงานเขียนสำคัญของเขาห้าชิ้น โดยมีข้อนำเสนอหลักว่า การเมืองของสก็อตต์ คือการเมืองที่ยืนอยู่ข้าง “พวกขี้แพ้” ในโลกรัฐศาสตร์ อันได้แก่ มวลชนชนชั้นล่างที่ไร้การจัดตั้งและคนป่าไร้รัฐ แทนที่จะเห็นว่าเป็น มวลชนที่ถูกครอบงำ ยอมจำนน ล้าหลัง ไร้อารยะ สก็อตต์มองคนเหล่านี้ว่าเป็นผู้กระทำการทางเมือง ต่อรอง ต่อต้าน และไม่ยอมจำนนต่ออำนาจของผู้ปกครองในทุกเมื่อเชื่อวัน ศิลปะในการต่อต้านของ “พวกขี้แพ้” นี้ครอบคลุมตั้งแต่การลอบทำลายทรัพย์สิน ลักเล็กขโมยน้อย ข่าวลือ วัฒนธรรมมุขปาฐะ ไปจนถึงเกษตรกรรมแบบตัดและเผา ในด้านหนึ่ง งานของสก็อตต์อาจถูกจัดได้ว่าเป็นงานประเภทท้องถิ่นนิยม ส่งเสริมวัฒนธรรมย่อยเฉพาะเจาะจงอันหลากหลาย  ในอีกด้านหนึ่ง งานของสก็อตทำให้เราทบทวนแนวคิดทางการเมืองของนักทฤษฎีรัฐศาสตร์สำคัญหลายคนอาทิ รุสโซ ชาร์ล ทิลลี่ และสลาวอย ชิเชค อีกทั้งยังสามารถเชื่อมโยงงานของเขากับประเด็นข้อถกเถียงทางรัฐศาสตร์ร่วมสมัยในโลกปัจจุบัน อาทิ การครอบงำทางอุดมการณ์ รัฐ อนาธิปไตย มาร์กซิสม์ ขบวนการเคลื่อนไหว และการปฏิวัติ
Action Research: Implementing a Strategy to Improve Post-Graduate Student Dissertation Evaluation & Feedback
Authors: Selvaratnam Naren
Published: October 2023

The following action research introduces deficits associated with dissertation evaluation of a masters in psychology program at a higher education institute in Colombo, Sri Lanka. It was identified that the chosen institute does not provide proper instructions and training for the academic staff to effectively assess post-graduate student dissertations. This has resulted in multiple score disputes and concerns over the dissertation moderation processes. Thus, the author has proposed a comprehensive strategy outlining an effective training program to support the academics of the institute to adopt a holistic assessment criteria against the existing rigid analytic criteria to help promote impartial and reason-based grades for students justifiable at external verification. This research may be of significance as it demonstrates the mechanisms involved in improving academic processes in a university. Further, this paper can be used as a guiding document to conduct future action research at university settings in Sri Lanka.
Personality traits that contribute to the non-recognition of lies
Authors: Yanovsky Mikhail Ivanovich , Malishevskaya Evgeniya Vladimirovna
Published: October 2023

In the era of the dominance of information technology, the problem of recognizing true and false information is becoming particularly relevant. The purpose of the article is to analyze the phenomenon of lying and the factors affecting its recognition. We believe that lying is not only a distortion of information, but also a form of intersubjective relations. The deceiver creates a closed "world" for the deceived, an information cocoon that replaces reality. This creates a relationship of different levels of two subjects, the deceiver and the deceived, their inequality and the imbalance of the situation. Sensitivity to unjustified inequality of psychological positions in relationships, to disequilibrium in the situation of relationships, according to our assumption, plays an important role in the recognition of lies. The article presents the results of a study of the influence of personality traits that contribute to the non-recognition of lies. An experiment was conducted in which research participants were asked to recognize 10 true and 10 false messages. According to the results of the experiment, the subjects were divided into two equal groups: relatively poorly recognizing lies and relatively well recognizing lies. The properties characteristic of those who do not recognize lies well turned out to be: the tendency to overestimate self-attitude (to put oneself above others), pragmatism, imperiousness, combined with emotional restraint, conformity, etc. Also, those who do not recognize lies are characterized by a lower level of integration and coherence of personal structures. There is some reason to say that poor lie recognition is also promoted by the lower importance of the moral factor in the relationship.
Per non essere Medea
Authors: Landi Patrizia
Published: October 2023

How are a tragedy by Euripides and a novella by Pirandello connected? How are their female protagonists, Medea and Mommina, similar? Despite the different literary genre they belong to, the Euripides tragedy and the Pirandello novella have a number of similar themes: betrayed love, a sense of estrangement even in one’s own home, jealousy. But with one major difference, the behavior toward one’s children: on the one hand killed perhaps because one is unable to find a different solution, on the other hand saved by any sacrifice even at the cost of one’s own life. And in the midst of all this the same drama that leads us to think that the ancient tragedy is not dead, but has only changed its skin.
Figlie di Medea
Authors: Zanini-Cordi Irene
Published: October 2023

Starting with the figure of Medea and, in particular, her rewriting in the novel Medea: Voices (1996) by Christa Wolf, this essay focuses on Olga, the protagonist of Elena Ferrante’s The Days of Abandonment (2002) and interrogates the abandonment-female identity nexus. It identifies the experience of abandonment as the catalyst for a crisis that leads the female subject to discover herself as “other”. In both Wolf’s and Ferrante’s characters, one can notice a procedure of reinterpretation of myth akin to that advocated by Adriana Cavarero in Despite Plato (1999). Indeed, the philosopher hypothesizes that “a new thought and a new unusual subject demand ‘new figures’ appropriate to female subjectivity insofar as they are thought by women”. Wolf’s ‘other’ Medea and Ferrant’s Olga come to understand the power structures on which society is based, they discover the crime perpetrated against the feminine, its silencing. This discovery leads to the fragmentation of identity that splinters into a polyphony of voices because, “I’ is a layered structure, made up of co-present voices”. In order not to fall into the “void of meaning”, the protagonists must find the strength to watch over themselves, to pay attention to themselves. No longer the Medea handed down to us from myth, then, but daughters suited to new thinking: though constrained, in telling themselves, by the limit of language, Wolf’s “other” Medea will make sense of herself by believing in her own intuition, while Ferrante’s Olga will pretend to believe in that social construction that is love.
Mechanical vibration patterns elicit behavioral transitions and habituation in crawling Drosophila larvae
Authors: Berne Alexander , Zhang Tom , Shomar Joseph , Ferrer Anggie J , Valdes Aaron , Ohyama Tomoko , Klein Mason
Published: October 2023

How animals respond to repeatedly applied stimuli, and how animals respond to mechanical stimuli in particular, are important questions in behavioral neuroscience. We study adaptation to repeated mechanical agitation using the Drosophila larva. Vertical vibration stimuli elicit a discrete set of responses in crawling larvae: continuation, pause, turn, and reversal. Through high-throughput larva tracking, we characterize how the likelihood of each response depends on vibration intensity and on the timing of repeated vibration pulses. By examining transitions between behavioral states at the population and individual levels, we investigate how the animals habituate to the stimulus patterns. We identify time constants associated with desensitization to prolonged vibration, with re-sensitization during removal of a stimulus, and additional layers of habituation that operate in the overall response. Known memory-deficient mutants exhibit distinct behavior profiles and habituation time constants. An analogous simple electrical circuit suggests possible neural and molecular processes behind adaptive behavior.
Genetic and dietary modulators of the inflammatory response in the gastrointestinal tract of the BXD mouse genetic reference population
Authors: Li Xiaoxu , Morel Jean-David , Benegiamo Giorgia , Poisson Johanne , Bachmann Alexis , Rapin Alexis , Sulc Jonathan , Williams Evan , Perino Alessia , Schoonjans Kristina , Bou Sleiman Maroun , Auwerx Johan
Published: October 2023

Inflammatory gut disorders, including inflammatory bowel disease (IBD), can be impacted by dietary, environmental, and genetic factors. While the incidence of IBD is increasing worldwide, we still lack a complete understanding of the gene-by-environment interactions underlying inflammation and IBD. Here, we profiled the colon transcriptome of 52 BXD mouse strains fed with a chow or high-fat diet (HFD) and identified a subset of BXD strains that exhibit an IBD-like transcriptome signature on HFD, indicating that an interplay of genetics and diet can significantly affect intestinal inflammation. Using gene co-expression analyses, we identified modules that are enriched for IBD-dysregulated genes and found that these IBD-related modules share cis-regulatory elements that are responsive to the STAT2, SMAD3, and REL transcription factors. We used module quantitative trait locus analyses to identify genetic loci associated with the expression of these modules. Through a prioritization scheme involving systems genetics in the mouse and integration with external human datasets, we identified Muc4 and Epha6 as the top candidates mediating differences in HFD-driven intestinal inflammation. This work provides insights into the contribution of genetics and diet to IBD risk and identifies two candidate genes, MUC4 and EPHA6, that may mediate IBD susceptibility in humans.
Bone canonical Wnt signaling is downregulated in type 2 diabetes and associates with higher advanced glycation end-products (AGEs) content and reduced bone strength
Authors: Leanza Giulia , Cannata Francesca , Faraj Malak , Pedone Claudio , Viola Viola , Tramontana Flavia , Pellegrini Niccolò , Vadalà Gianluca , Piccoli Alessandra , Strollo Rocky , Zalfa Francesca , Beeve Alec T , Scheller Erica L , Tang Simon Y , Civitelli Roberto , Maccarrone Mauro , Papalia Rocco , Napoli Nicola
Published: October 2023

Type 2 diabetes (T2D) is associated with higher fracture risk, despite normal or high bone mineral density. We reported that bone formation genes (SOST and RUNX2) and advanced glycation end-products (AGEs) were impaired in T2D. We investigated Wnt signaling regulation and its association with AGEs accumulation and bone strength in T2D from bone tissue of 15 T2D and 21 non-diabetic postmenopausal women undergoing hip arthroplasty. Bone histomorphometry revealed a trend of low mineralized volume in T2D (T2D 0.249% [0.156–0.366]) vs non-diabetic subjects 0.352% [0.269–0.454]; p=0.053, as well as reduced bone strength (T2D 21.60 MPa [13.46–30.10] vs non-diabetic subjects 76.24 MPa [26.81–132.9]; p=0.002). We also showed that gene expression of Wnt agonists LEF-1 (p=0.0136) and WNT10B (p=0.0302) were lower in T2D. Conversely, gene expression of WNT5A (p=0.0232), SOST (p<0.0001), and GSK3B (p=0.0456) were higher, while collagen (COL1A1) was lower in T2D (p=0.0482). AGEs content was associated with SOST and WNT5A (r=0.9231, p<0.0001; r=0.6751, p=0.0322), but inversely correlated with LEF-1 and COL1A1 (r=–0.7500, p=0.0255; r=–0.9762, p=0.0004). SOST was associated with glycemic control and disease duration (r=0.4846, p=0.0043; r=0.7107, p=0.00174), whereas WNT5A and GSK3B were only correlated with glycemic control (r=0.5589, p=0.0037; r=0.4901, p=0.0051). Finally, Young’s modulus was negatively correlated with SOST (r=−0.5675, p=0.0011), AXIN2 (r=−0.5523, p=0.0042), and SFRP5 (r=−0.4442, p=0.0437), while positively correlated with LEF-1 (r=0.4116, p=0.0295) and WNT10B (r=0.6697, p=0.0001). These findings suggest that Wnt signaling and AGEs could be the main determinants of bone fragility in T2D.
Increase of cell surface vimentin is associated with vimentin network disruption and subsequent stress-induced premature senescence in human chondrocytes
Authors: Riegger Jana , Brenner Rolf E
Published: October 2023

Accumulation of dysfunctional chondrocytes has detrimental consequences on the cartilagehomeostasis and is thus thought to play a crucial role during the pathogenesis of osteoarthritis(OA). However, the underlying mechanisms of phenotypical alteration in chondrocytes areincompletely understood. Here, we provide evidence that disruption of the intracellularvimentin network and consequent phenotypical alteration in human chondrocytes results in anexternalization of the intermediate filament. The presence of the so-called cell surfacevimentin (CSV) on chondrocytes was associated with the severity of tissue degeneration inclinical OA samples and was enhanced after mechanical injury of cartilage tissue. By meansof a doxorubicine-based in vitro model of stress-induced premature senescence (SIPS), wecould confirm the connection between cellular senescence and amount of CSV. AlthoughsiRNA-mediated silencing of CDKN2A clearly reduced the senescent phenotype as well asCSV levels of human chondrocytes, cellular senescence could not be completely reversed.Interestingly, knockdown of vimentin resulted in a SIPS-like phenotype and consequentlyincreased CSV. Therefore, we concluded that the integrity of the intracellular vimentinnetwork is crucial to maintain cellular function in chondrocytes. This assumption could beconfirmed by chemically- induced collapse of the vimentin network, which resulted in cellularstress and enhanced CSV expression. Regarding its biological function, CSV was found to beassociated with enhanced chondrocyte adhesion and plasticity. While osteogenic capacitiesseemed to be enhanced in chondrocytes expressing high levels of CSV, the chondrogenicpotential was clearly compromised. Overall, our study reinforces the importance of thevimentin network in maintenance of the chondrogenic phenotype and introduces CSV as anovel membrane-bound marker of dysfunctional chondrocytes.
Assessment tools and incidence of hospital-associated disability in older adults: a rapid systematic review
Authors: Giacomino Katia , Hilfiker Roger , Beckwée David , Taeymans Jan , Sattelmayer Karl Martin
Published: October 2023

Background

During hospitalization older adults have a high risk of developing functional impairments unrelated to the reasons for their admission. This is termed hospital-associated disability (HAD). This systematic review aimed to assess the incidence of HAD in older adults admitted to acute care with two outcomes: firstly in at least one activity of daily living from a set of functional tasks (e.g., Katz Index) and secondly the incidence of functional decline in an individual functional task (e.g., bathing), and to identify any tools or functional tasks used to assess activities of daily living (ADL) in hospitalized older patients.

Methods

A rapid systematic review was performed according to the recommendations of the Cochrane Rapid Reviews Methods Group and reported the data according the PRISMA statement. A literature search was performed in Medline (via Ovid), EMBASE, and Cochrane Central Register of Controlled Trials databases on 26 August 2021. Inclusion criteria: older adults (≥65 years), assessment of individual items of activities of daily living at baseline and discharge. Exclusion criterion: studies investigating a specific condition that could affect functional decline and studies that primarily examined a population with cognitive impairment. The protocol was registered on OSF registries (https://osf.io/9jez4/) identifier: DOI 10.17605/OSF.IO/9JEZ4.

Results

Ten studies were included in the final review. Incidence of HAD (overall score) was 37% (95% CI 0.30–0.43). Insufficient data prevented meta-analysis of the individual items. One study provided sufficient data to calculate incidence, with the following values for patients’ self-reported dependencies: 32% for bathing, 27% for dressing, 27% for toileting, 30% for eating and 27% for transferring. The proxy reported the following values for patients’ dependencies: 70% for bathing, 66% for dressing, 70% for toileting, 61% for eating and 59% for transferring. The review identified four assessment tools, two sets of tasks, and individual items assessing activities of daily living in such patients.

Conclusions

Incidence of hospital-associated disability in older patients might be overestimated, due to the combination of disease-related disability and hospital-associated disability. The tools used to assess these patients presented some limitations. These results should be interpreted with caution as only one study reported adequate information to assess the HAD incidence. At the item level, the latter was higher when disability was reported by the proxies than when it was reported by patients. This review highlights the lack of systematic reporting of data used to calculate HAD incidence. The methodological quality and the risk of bias in the included studies raised some concerns.
Transcriptome analysis reveals the mechanism of pyroptosis-related genes in septic cardiomyopathy
Authors: Zhu Haoyan , Wu Jiahe , Li Chenze , Zeng Ziyue , He Tianwen , Liu Xin , Wang Qiongxin , Hu Xiaorong , Lu Zhibing , Cai Huanhuan
Published: October 2023

Background

Septic cardiomyopathy (SC) is characterized by myocardial dysfunction caused by sepsis and constitutes one of the serious complications of sepsis. Pyroptosis is a unique proinflammatory programmed cell death process. However, the role of pyroptosis in the development of SC remains unclear, and further study is required. The purpose of this study is to identify pyroptosis-related genes (PRGs) in SC and explore the mechanism of pyroptosis involved in the regulation of SC formation and progression.

Methods

Differential expression analysis and enrichment analysis were performed on the SC-related dataset GSE79962 to identify differentially expressed genes (DEGs). PRGs were screened by intersecting genes associated with pyroptosis in previous studies with the DEGs obtained from GSE79962. The expression pattern of them was studied based on their raw expression data. Additionally, corresponding online databases were used to predict miRNAs, transcription factors (TFs) and therapeutic agents of PRGs. Lipopolysaccharide (LPS)-induced cell damage models in H9C2 and AC16 cell lines were constructed, cell activity was detected by CCK-8 and cell pyroptosis were detected by Hoechst33342/PI staining. Furthermore, these PRGs were verified in the external datasets (GSE53007 and GSE142615) and LPS-induced cell damage model. Finally, the effect of siRNA-mediated PRGs knockdown on the pyroptosis phenotype was examined.

Results

A total of 1,206 DEGs were screened, consisting of 663 high-expressed genes and 543 low-expressed genes. Among them, ten PRGs (SOD2, GJA1, TIMP3, TAP1, TIMP1, NOD1, TP53, CPTP, CASP1 and SAT1) were identified, and they were mainly enriched in “Pyroptosis”, “Ferroptosis”, “Longevity regulating pathway”, and “NOD-like receptor signaling pathway”. A total of 147 miRNAs, 31 TFs and 13 therapeutic drugs were predicted targeting the PRGs. The expression trends of SOD2 were confirmed in both the external datasets and LPS-induced cell damage models. Knockdown of SOD2 induced increased pyroptosis in the AC16 LPS-induced cell damage model.

Conclusions

In this study, we demonstrated that SOD2 is highly expressed in both the SC and LPS-induced cell damage models. Knockdown of SOD2 led to a significant increase in pyroptosis in the AC16 LPS-induced cell damage model. These findings suggest that SOD2 may serve as a potential target for the diagnosis and treatment of SC.
Sentidos epistemológicos de la educación religiosa escolar según las y los docentes : el proceso de diseño curricular del Programa de Religión Católica
Authors:   , Barruel Ayala Daniela Soledad
Published: October 2023

El presente Proyecto de Magíster es un estudio sobre los sentidos epistemológicos de la Educación Religiosa Escolar expresados por las y los docentes durante el diseño curricular del Programa de Religión Católica que entró en vigencia el 2021. Dicho proceso se desarrolló de manera colaborativa, con la participación de profesores de las diócesis de todo Chile entre jornadas de trabajo durante el 2018 y el 2019. El estudio parte desde el interés por la disciplina escolar de Religión, la que tiene particularidades epistemológicas, pues existen diferentes enfoques sobre cómo tratar dicha disciplina en la escuela, entre ellos posiciones más confesionales hasta perspectivas que descartan por completo una postura confesional en la asignatura. Los resultados del análisis de los datos dan cuenta de cuatro sentidos epistemológicos: (1) Actitud religiosa, en este enfoque se pretende que las y los estudiantes puedan hacer juicios, discernir y, actuar desde una mirada católica frente a los problemas personales y sociales. El sentido referido a la (2) Relación con Dios está centrado en la experiencia de fe y pretende que la Educación Religiosa Escolar propicie espacios de encuentro con Dios y con Cristo. El tercer sentido identificado es (3) Ser parte de la Iglesia, desde esta perspectiva se espera que las y los alumnos formen parte del proceso de renovación de la Iglesia y, se les educa para su participación en estos espacios. Finalmente, la (4) Dimensión Religiosa, toma una postura que difiere de las anteriores pues, no tiene como intención que la o el educando adhiera a un credo religioso, sino, que conozca la religión, la identidad cristiana y reflexione sobre el sentido.
Decisiones curriculares en el contexto de pandemia por COVID-19 en la asignatura de Educación Física y Salud: estudio en tres establecimientos educacionales de Santiago de Chile
Authors:   , Matos González Anabel
Published: October 2023

Esta investigación tuvo como objetivo examinar las decisiones curriculares tomadas en tres establecimientos educacionales de Santiago respecto a la asignatura Educación Física y Salud en el contexto de pandemia por Covid-19, identificando así las acciones llevadas a cabo tanto a nivel meso (establecimiento), como a nivel micro (profesores) en un contexto tan diferente al acostumbrado. Se llevó a cabo una investigación cualitativa de tipo indagación. La muestra estuvo compuesta por tres profesores de la asignatura, los cuales laboraban en establecimientos educacionales de tres dependencias diferentes: establecimiento municipal, subvencionado y privado. El instrumento para la recolección de los datos fue la entrevista. También se consideró el análisis del PEI de cada establecimiento. Los principales resultados dieron cuenta de que en las tres instituciones se acortó el tiempo del plan de estudio, se consideró no usar las Bases Curriculares y en su lugar utilizar la Priorización Curricular. También se tomaron decisiones sobre qué contenidos incluir al currículum considerando factores como el contexto, los recursos, el sentir y situación de los estudiantes, las opiniones de los apoderados y factibilidad de desarrollar los contenidos curriculares.
Levantamiento de percepciones docentes para la elaboración de un plan de desarrollo profesional en un colegio particular de Santiago
Authors:   , Rodríguez Contreras Carolina Solange
Published: October 2023

El informe presenta un proyecto de implementación en un colegio particular pagado de Santiago, cuyo objetivo final es diseñar un plan de formación docente que permita a los líderes académicos del establecimiento promover el cambio de metodologías de aula, con el propósito de concretar el proyecto educativo declarado. La institución se enfrenta a un desafío definido por el sostenedor, de innovar en el aula para desarrollar competencias del siglo XXI en sus estudiantes, y entregar así, una educación integral pertinente a los tiempos de hoy. El plan permitirá desarrollar procesos de formación de manera sistemática y permanente, que pueden evaluarse y socializarse con la comunidad, constituyéndose así, un nuevo plan de gestión pedagógica que permita ordenar acciones de capacitación y acompañamiento, que hoy son aisladas y desvinculadas entre sí. La implementación del cuestionario online desarrollado para este estudio, permitió identificar prácticas en las que los docentes se percibían con mayor o menor seguridad a la hora de desarrollarlas, lo que posibilitó, en el análisis de estos resultados junto al equipo directivo académico del establecimiento, la reflexión en torno a los procesos pedagógicos, basándonos en evidencia para la toma de decisiones en la gestión, específicamente en este caso, los procesos de formación docente.
Constructo de ciudadanía: presencia de principios y valores cívico-ciudadanos en el diseño curricular dominicano de Ciencias Sociales del Nivel Secundario, Segundo Ciclo, Modalidad Académica
Authors:   , León Heredia Isidro de
Published: October 2023

El objetivo de esta investigación es caracterizar la presencia de un conjunto de principios y valores cívico-ciudadanos, contenidos en el currículum dominicano vigente de Ciencias Sociales del Nivel Secundario, Modalidad Académica. La metodología en esta investigación es mixta. El estudio tuvo tres niveles de análisis. El primer nivel consistió en un recuento cuantitativo de los valores presentes en los documentos curriculares: las Bases de la Revisión y Actualización y el diseño curricular de la asignatura. El segundo examinó los significados de los valores de mayor mención, y el tercer nivel, analizó los tipos de aprendizaje asociados a los valores de mayor presencia en el diseño de la asignatura. Los resultados muestran que los valores de mayor presencia en el diseño de la asignatura de Ciencias Sociales son derechos humanos y democracia. Por otra parte, el concepto derecho humanos promueve varias fuentes de significados, entre ellos, responsabiliza al Estado en garantizar la democracia, la defensa y la construcción de una conciencia crítico-reflexiva. Respecto al valor democracia, este distingue dos campos de análisis: la participación formal y las instituciones. Concerniente a los tipos de aprendizaje en el diseño, el valor derechos humanos se encuentra presente en las habilidades o contenidos de procedimientos, que desde Delors (1996) se traducen a un saber hacer. Finalmente, el valor democracia prioriza mayormente conocimientos de tipo conceptual. Según Delors, este conocimiento se convierte en un saber conocer o un saber intelectual.