bluuebunny/crossref_metadata_2025 huggingface dataset:
FORMULATION, CHARACTERIZATION AND IN-VITRO DISSOLUTION STUDIES OF METADOXINE TABLETS PREPARED BY VARIOUS GRANULATION METHODS
Authors:   Gosavi College of Pharmaceutical Education and Research, Nashik, Maharashtra, India, Pingale Prashant L.
Published: May 2021

Pharmaceutical tablets are robust, flat, or biconvex dishes, according to the Indian Pharmacopoeia. Depending on a range of medicinal substances, they vary in shape and differ greatly in size and weight. In the era of increasing health awareness and strict standards set by regulatory authorities such as the US FDA, WHO, and globalization, it has become mandatory for the producer to launch a product cost-effectively. In the tablet dosage form, two classes of drugs are administered orally. Narrow extensions of the parietal peritoneum that suspend the diaphragm's liver are the right and left coronary ligaments. To produce an effective and reliable product, the drug must have a fine particle size and a large surface area. The tablet coating takes place inside a perforated rotating drum in a controlled atmosphere. Tablets are lifted and turned into the center of the drum from the sides. To make the tablet surface easier to swallow, every tablet surface is exposed to an even amount of deposited/sprayed coating. The purpose of the present investigation is to formulate a tablet of Metadoxine, which improves cognitive impairment and the main psychological symptoms due to occasional or prolonged alcohol abuse, such as aggressiveness, agitation, mood, and behavioral disturbances. The tablets were prepared using direct compression, dry granulation, and wet granulation method and a comparison of the same with an innovator’s product. Keywords: Tablets, Metadoxine, Dry granulation, direct compression, wet granulation.
Ground Heat Accumulator for Backup Heat Supply of Energy Facilities
Authors:   Orlovsky State Agrarian University named after N.V. Parakhin, Sopov Anatoliy I. , Vinogradov Aleksandr ,   Federal Scientific Agroengineering Center VIM
Published: May 2021

Many power grid facilities require heating in winter. For their heating, they usually install a system of electric heaters, connect mini gas boilers or use the thermal emissions of working electrical installations, since these objects are often located away from the sources of central heating. This leads to additional costs for the organization's own needs. It is proposed to accumulate the excess heat generated by using a ground heat accumulator, which will allow you to accumulate heat in warm periods of the year and when there is an excess of thermal energy in the system, and then use the thermal energy of the accumulator to heat the object. (Research purpose) The research purpose is in developing a ground heat accumulator capable of accumulating excess heat energy generated during the operation of high-power transformers and, if necessary, to transfer the accumulated heat to the heat supply system of energy facilities. (Materials and methods) The article considers the advantages of introducing heat storage in the heat supply systems of various facilities. Authors conducted a literary analysis of various methods of heat accumulation. (Results and discussion) The article presents the justification for the choice of a ground heat accumulator. Authors have completed the description of the proposed battery and the technology of its creation. The article describes the method of calculation of the main elements of the selected type of heat accumulator and the quantitative characteristics of the accumulator on the example of real objects. The article describes the operation of the battery in interaction with a heat pump and a horizontal ground heat exchanger. (Conclusions) The use of a heat accumulator as a backup source for energy facilities allows organizations to reduce the cost of heating premises and equipment. Additional functions that the ground heat accumulator is capable of performing are identified.
Influence of Environmental Parameters on the Output Power of the Wind Power Plant of a Renewable Energy Complex
Authors:   Federal Scientific Agroengineering Center VIM, Morenko Konstantin , Morenko Sergey ,   Russian Open Academy of Transport of Russian University of Transport
Published: May 2021

The wind speed has the greatest influence on the power flow, since it is included in the power equation in the third degree. It is impossible to ignore the presence in the equation of the air density, which is affected by its temperature, pressure and humidity. The air density is most often chosen according to the conditions of the standard atmosphere. The concept of a standard atmosphere varies from source to source and depends on the field of study. (Research purpose) The research purpose is in studying the influence of temperature, pressure and humidity on the power of the wind flow. (Materials and methods) The article presents existing works on the effect of air density on the operation of wind turbines. Authors selected sources that use the parameters available for measurement, for which there is statistical meteorological data. The study uses the temperature, pressure and relative humidity of the air as data with extensive meteorological observations. (Results and discussion) The article considers the influence of each of the factors depending on the levels of the other factors. The temperature change from -40 to +60 degrees Celsius at low pressure gives a deviation spread of 36.43 percent, while at high pressure this spread is 39.42 percent. A similar situation is observed with pressure, the influence of which varies in the range of 6.97-9.96 percent. The most unfavorable combination of factors (high pressure, low temperature and humidity versus low pressure, high temperature and humidity demonstrated an effect of up to 46.39 percent. (Conclusions) Temperature has the greatest impact on air density and power flow, and humidity has almost no effect on air density and power flow. With the most unfavorable combination of factors, the power flow through the wind wheel can decrease almost to one and a half times while maintaining its speed. The influence of air temperature cannot be ignored when calculating the power of the wind flow.
Automated Control of the Microclimate of Greenhouses
Authors:   Federal Scientific Agroengineering Center VIM, Ukhanova Viktoriya
Published: May 2021

The protected soil industry is one of the most technologically complex and energy-intensive branches of agriculture. In recent years, especially in 2020, the demand for the products of greenhouse plants is increasing. Reducing the risks of the impact of the quality of energy supply, as well as reducing the cost of electricity due to the constant increase in tariffs are important tasks. Therefore, it is important to identify and analyze modern available technologies and equipment of Russian production for greenhouse farms. (Research purpose) The research purpose is in assessing the impact of the quality of energy supply on the technological processes of greenhouse farms, identifying and analyzing the existing modern domestic equipment that reduces the risks of the energy supply. (Materials and methods) Authors used a computational and analytical method for determining the average indicators of electric energy costs for technological processes in a greenhouse. The article presents a review of the automated greenhouse microclimate management system developed using the products of TM OWEN. (Results and discussion) Automated systems for controlling the greenhouse microclimate can reduce the impact of the quality of energy supply when deviating from normal values, minimize the impact of the human factor on the production process, and collect and archive the indicators of devices for further analysis. The system makes it possible to repair and replace failed equipment without stopping the production process and implies both fully automated and manual control, if necessary. The considered version of the automated greenhouse microclimate control system has been tested in practice and is used in the greenhouse economy of the Republic of Bashkortostan. (Conclusions) The efficiency of the greenhouse economy depends, among other things, on the level of automation, the quality of energy supply, and the use of energy-saving technologies. We stated that it is necessary to continue to work on the identification and analysis of modern Russian-made equipment, informing agricultural producers about the best available technologies.
Усадьба Ильинское: утраченный памятник в культуре
Authors: Слюнькова Инесса
Published: May 2021

Статья поднимает проблему нашего будущего простран­ственного окружения, которая решается сегодня в конфликте сохранения традиций и замещения объектов ценного, семан­тически значимого наследия новым частным строительством. Объектом исследования является архитектура подмосковной усадьбы Ильинское, в назначении резиденции Александра II, царской семьи, историко-культурное значение которой не получило объективной оценки в культуре.

Проводятся параллели между теорией литературы XIX века и программой обустройства императорского имения Ильинское. На первое место выходят понятия эпического жанра литературы и архитектуры, понятия физической и нрав­ственной красоты ансамбля усадьбы. Во внимание принима­ется изначально присущая эпосу и мифу система внутренних конфликтов, указывающая на пути направления будущего.

Работа опирается на вновь выявленные документальные изобразительные материалы. Впервые представлены литогра­фия «Народный праздник 20 июля 1869 года в Ильинском»; акварель Альб. Н. Бенуа с видом дворца; в полном объёме серия 14 фотографий усадьбы мастерской Шерер.

Затронута тема личностных моральных рисков использо­вания территорий, обладающих высокой степенью мемори­альной ценности.
PEMBERDAYAAN PEREMPUAN MELALUI PELATIHAN PEMANFAATAN KAIN PERCA SEBAGAI AKSESORIS MELALUI MEDIA YOUTUBE DI LSM BENING SAGULING
Authors: Zakia Tsaniatu
Published: May 2021

AbstractThis research is motivated bye the large amount of spare time owned by housewives ehich has not been used optimally, but this free time is used to play smartphones. The purpose of this research is to describe in more detail about women's empowerment through training on the use of patchwork as accessories through Youtube media in Bening Saguling. This study uses a descriptive method with a qualitative approach, which is the subject of this study, one training Instructor and 10 housewives. While the data collection technique is by means of observation, interview and documentation. The result of this training is to provide patchwork skills for low-educated women, providing a skill that can be of personal use and of sale value. The benefits of this activity are that the work can be sold so that it is expected to be able to improve the standard of living of the community and fill women's spare time with more useful activities.
La transparencia y la rendición de cuentas mecanismos del “gobierno abierto” como instrumento de compromiso público y responsabilidad democrática en las organizaciones públicas
Authors: Home Arias Patricia , Arévalo Juan Camilo
Published: May 2021

Los debates que se han desarrollado alrededor de la Administración Pública en América Latina y la adopción de la Nueva Gestión Pública (NGP) por parte de las organizaciones; dan cuenta de un enfoque intergubernamental al dejar de lado la participación del ciudadano. El presente documento tiene como objetivo evidenciar la relación entre la rendición de cuentas y la transparencia, por medio de un parangón entre el modelo burocrático, la Nueva Gestión Pública y la post-NGP. Se concluye, que el Gobierno Abierto es un nuevo modelo de gobierno; en el cual, el ciudadano a diferencia de los modelos burocrático y de la Nueva Gestión Pública (NGP) posee un rol activo, partiendo de la colaboración en el co-diseño de políticas públicas, así como la solución de problemáticas comunes, haciendo uso de las Tecnologías de la Información y la Comunicación (TIC).
The impact of board of directors’ characteristics on dividend policy: Evidence from a developing country
Authors: Dissanayake Kasun Tharaka , Dissabandara Hareendra
Published: May 2021

The “dividend puzzle” has been an unresolved problem since the 1950s. The purpose of this paper is to investigate the nature and a level of the relationship between board characteristics dividend policy. The study used a positivistic approach and Spearman correlation metric, descriptive statistics, and binary regression models have been deployed as analytical tools. It is found that food and beverages sector had the highest percentage for dividend payout from 2015 to 2019. The highest percentage for women on boards was 13% in the land and property sector. The average board size for the selected companies was 8. The likelihood to pay dividends, women on boards, the board size, and CEO duality indicated a significant positive relationship. Panel regression results indicate that there is no significant relationship between board characteristics and the level of dividend payment for the selected sample. But in a sectorial analysis audit committee size has a significant negative relationship with the level of dividend payment in the manufacturing sector whereas board gender diversity has a significant positive relationship with the same in the food and beverage sector. In summary, dividend decision has been affected by several board characteristics, but such factors had no significant impact on the level of dividends declared in the market. The sectorial analysis revealed that several characteristics affected the level of dividends in two sectors
Evolution of prudent predation in complex food webs: mechanism and evidence
Authors: Al-Khudhairy Orestes Gutierrez , Rossberg Axel
Published: May 2021

Prudent predators catch sufficient prey to sustain their populations
but not as much as to undermine their populations’ survival. The
idea that predators evolve to be prudent has been dismissed in the
1970s, but the blunt arguments invoked then are untenable in light
of modern evolution theory. Evolution of prudent predation has
repeatedly been demonstrated in two-species predator-prey
metacommunity models. However, the vigorous population fluctuations
that these models predict are not widely observed. Here we show
that in complex model food-webs prudent predation evolves by a
different mechanism. We make testable predictions for empirical
signatures of this mechanism and its outcomes. Then we discuss how
these predictions are borne out across freshwater, marine, and
terrestrial ecosystems. Demonstrating explanatory power of evolved
prudent predation well beyond the question of predator-prey
coexistence, the predicted signatures explain unexpected declines of
invasive alien species, the shape of stock-recruitment relations of
fish, and the clearance rates of pelagic consumers across the
latitudinal gradient and 15 orders of magnitude in body mass.
Specific research to further test and mobilise the utility of this
theory is proposed.
Double-Loop Learning and Productive Reasoning: Chris Argyris’s Contributions to a Framework for Lifelong Learning and Inquiry
Authors: Clark Kevin
Published: May 2021

This article reviews social scientist and organizational researcher Chris Argyris’s publications from the 1970s through the 2000s about organizational learning. In his role as an action scientist and consultant, working to facilitate learning in organizational contexts and drawing on earlier work in psychology from John Dewey and Kurt Lewin, Argyris developed his “theory of action” perspective on learning and interpersonal inquiry. According to Argyris, learning involves increasing the effectiveness of our actions so as to produce the intended results. He argued, however, that we are often unaware of the extent to which our actions inhibit learning in social contexts. Argyris sought to identify defensive routines that inhibit learning at the individual, group, intergroup, and organizational levels and promoted a shift from single-loop to double-loop learning and from defensive (Model I) to productive (Model II) reasoning. In this article, based on Argyris’s work, I construct a general framework of principles and action heuristics for lifelong learning and inquiry, applicable across organizational, professional, and everyday contexts. After reviewing basic concepts of Argyris’s theory of organizational learning, I identify principles and strategies for individuals seeking to develop in themselves, as well as to promote in others, an orientation of general lifelong learning and inquiry.
Effects of States’ Laws on Youth Physical Activity Participation and Obesity Prevalence
Authors: Chang Chae
Published: May 2021

The alarming prevalence of obesity and lack of physical activity among adolescents led to immediate policy action to address these concerns. Accordingly, many states introduced and enacted their own legislation to encourage physical activity in schools. Few studies have explored the effectiveness of the new legislation, however, especially at the state level. To answer the fundamental question of whether policy is effective and to describe the varying effects of state obesity policies, this study analyzed the Youth Risk Behavior Surveillance System from 2007 to 2017. Using the difference-in-differences method, this study found that legislative efforts to encourage physical activity had a significant and substantial effect on enhancing physical-activity participation and reducing adolescent obesity; however, subgroup analyses revealed that the effect was concentrated on female and white adolescents only. Additionally, the subsequent sensitivity analysis revealed that since 2015, when national attention started to divert to new health concerns (opioid abuse, for example), physical activity levels pulled back to 2009 levels. Rates of obesity and overweight have been on a sharp rise again since 2015. Lawmakers should reconsider changes in the law merging physical environments with digital environments, particularly for members of Generation Alpha, who will have ever more enticements for screen time.
The Case for a Greenpeace Apology to Newfoundland and Labrador
Authors: Burke Danita Catherine
Published: May 2021

Greenpeace’s early work in the anti-sealing movement in the 1970s–1980s is a complex legacy for the organization to navigate. While Greenpeace Canada withdrew from the anti-sealing movement in 1986 and expressed regret for the impact of its actions on Inuit, the extent of the long-term damage caused by the anti-sealing movement, and Greenpeace’s controversial track record in it, motivated Greenpeace Canada to articulate a more robust public apology to Canadian Inuit in 2014. This commentary outlines a case for Greenpeace to continue its path of reconciliation for activities undertaken during the anti-sealing movement and to apologize to the people of Newfoundland and Labrador. Particularly, the commentary calls for an apology to sealers, their families, and their communities, and to First Nations and Inuit people from the province, for Greenpeace’s role in inflicting and promoting forms of violence, stigma, and cultural hatred, and in undermining Indigenous rights in the province.
Serendipity in Accounting: Teaching Students How to Navigate a Changing World
Authors: Klevsky Elena , Huber Marsha M.
Published: May 2021

Serendipity is what happens when individuals achieve a positive outcome as a result of a chance encounter with unsought information that they have the knowledge, skill, and ability to properly process and act upon. Learning how to achieve serendipity may prove vital for the accounting profession, especially in a changing world where accountants need to expect the unexpected and respond to it appropriately. As a skill, serendipity can be developed in the accounting classroom, but it is not currently taught in business schools. This article provides accounting educators with resources to teach students about serendipity and gives suggestions on how to design serendipity activities for accounting classes that can help students develop a serendipity mindset.
Prestige Projects Limited: Challenges in Transitioning to New Accounting Policy
Authors: Barua Samir K. , Gujarathi Mahendra R.
Published: May 2021

This case provides an experiential learning opportunity to (1) appreciate the role of professional judgment in accounting policy choices, (2) evaluate the effect of accounting decisions on other business functions, and (3) understand the challenges in transitioning to a new accounting policy. Prestige's previous auditors had allowed the use of output-based measure (milestones completed) to compute the percentage-of-completion (POC) for its long-term construction contracts. The newly appointed auditors recommended switching to input-based measures (costs incurred) to compute POC. Students must choose the appropriate financial reporting policy, considering accounting and non-accounting issues. The case addresses an important context because almost one in every eight large 500 companies is engaged in long-term construction contracts (AICPA 2013). Although the case setting is in India, it can be used in any country given its GAAP-agnostic nature. The case is best suited for intermediate accounting courses in which the topic of revenue recognition is addressed.
Metabolomics Profiling of Patients With A−β+ Ketosis-Prone Diabetes During Diabetic Ketoacidosis
Authors: Jahoor Farook , Hsu Jean W. , Mehta Paras B. , Keene Kelly R. , Gaba Ruchi , Mulukutla Surya Narayan , Caducoy Eunice , Peacock W. Frank , Patel Sanjeet G. , Bennet Rasmus , Lernmark Ake , Balasubramanyam Ashok
Published: May 2021

When stable and near-normoglycemic, patients with “A−β+” ketosis-prone diabetes (KPD) manifest accelerated leucine catabolism and blunted ketone oxidation, which may underlie their proclivity to develop diabetic ketoacidosis (DKA). To understand metabolic derangements in A−β+ KPD patients during DKA, we compared serum metabolomics profiles of adults during acute hyperglycemic crises, without (n = 21) or with (n = 74) DKA, and healthy control subjects (n = 17). Based on 65 kDa GAD islet autoantibody status, C-peptide, and clinical features, 53 DKA patients were categorized as having KPD and 21 type 1 diabetes (T1D); 21 nonketotic patients were categorized as having type 2 diabetes (T2D). Patients with KPD and patients with T1D had higher counterregulatory hormones and lower insulin-to-glucagon ratio than patients with T2D and control subjects. Compared with patients withT2D and control subjects, patients with KPD and patients with T1D had lower free carnitine and higher long-chain acylcarnitines and acetylcarnitine (C2) but lower palmitoylcarnitine (C16)-to-C2 ratio; a positive relationship between C16 and C2 but negative relationship between carnitine and β-hydroxybutyrate (BOHB); higher branched-chain amino acids (BCAAs) and their ketoacids but lower ketoisocaproate (KIC)-to-Leu, ketomethylvalerate (KMV)-to-Ile, ketoisovalerate (KIV)-to-Val, isovalerylcarnitine-to-KIC+KMV, propionylcarnitine-to-KIV+KMV, KIC+KMV-to-C2, and KIC-to-BOHB ratios; and lower glutamate and 3-methylhistidine. These data suggest that during DKA, patients with KPD resemble patients with T1D in having impaired BCAA catabolism and accelerated fatty acid flux to ketones—a reversal of their distinctive BCAA metabolic defect when stable. The natural history of A−β+ KPD is marked by chronic but varying dysregulation of BCAA metabolism.
Intralymphatic Glutamic Acid Decarboxylase With Vitamin D Supplementation in Recent-Onset Type 1 Diabetes: A Double-Blind, Randomized, Placebo-Controlled Phase IIb Trial
Authors: Ludvigsson Johnny , Sumnik Zdenek , Pelikanova Terezie , Nattero Chavez Lia , Lundberg Elena , Rica Itxaso , Martínez-Brocca Maria A. , Ruiz de Adana Marisol , Wahlberg Jeanette , Katsarou Anastasia , Hanas Ragnar , Hernandez Cristina , Clemente León Maria , Gómez-Gila Ana , Lind Marcus , Lozano Marta Ferrer , Sas Theo , Samuelsson Ulf , Pruhova Stepanka , Dietrich Fabricia , Puente Marin Sara , Nordlund Anders , Hannelius Ulf , Casas Rosaura
Published: May 2021

OBJECTIVE

To evaluate the efficacy of aluminum-formulated intralymphatic glutamic acid decarboxylase (GAD-alum) therapy combined with vitamin D supplementation in preserving endogenous insulin secretion in all patients with type 1 diabetes (T1D) or in a genetically prespecified subgroup.

RESEARCH DESIGN AND METHODS

In a multicenter, randomized, placebo-controlled, double-blind trial, 109 patients aged 12–24 years (mean ± SD 16.4 ± 4.1) with a diabetes duration of 7–193 days (88.8 ± 51.4), elevated serum GAD65 autoantibodies, and a fasting serum C-peptide >0.12 nmol/L were recruited. Participants were randomized to receive either three intralymphatic injections (1 month apart) with 4 μg GAD-alum and oral vitamin D (2,000 IE daily for 120 days) or placebo. The primary outcome was the change in stimulated serum C-peptide (mean area under the curve [AUC] after a mixed-meal tolerance test) between baseline and 15 months.

RESULTS

Primary end point was not met in the full analysis set (treatment effect ratio 1.091 [CI 0.845–1.408]; P = 0.5009). However, GAD-alum–treated patients carrying HLA DR3-DQ2 (n = 29; defined as DRB1*03, DQB1*02:01) showed greater preservation of C-peptide AUC (treatment effect ratio 1.557 [CI 1.126–2.153]; P = 0.0078) after 15 months compared with individuals receiving placebo with the same genotype (n = 17). Several secondary end points showed supporting trends, and a positive effect was seen in partial remission (insulin dose–adjusted HbA1c ≤9; P = 0.0310). Minor transient injection site reactions were reported.

CONCLUSION

Intralymphatic administration of GAD-alum is a simple, well-tolerated treatment that together with vitamin D supplementation seems to preserve C-peptide in patients with recent-onset T1D carrying HLA DR3-DQ2. This constitutes a disease-modifying treatment for T1D with a precision medicine approach.
Effects of laser shock peening on the properties and microstructure evolution of laser-polished surface of Cr12 steel
Authors: Chen Huan , Wei Chaoyang , Wang Shengshui , Jiang Zhigang , Peng Xiaocong , Cao Zhen , Shao Jianda
Published: May 2021

Laser polishing efficiently reduces the surface roughness of die steel, but at the same time, residual tensile stress is induced on the surface, leading to crack initiation and propagation. The present study induces residual compressive stress on the laser-polished surface of Cr12 steel by laser shock peening. The surface residual stress of samples, which underwent different treatments, is measured and compared. The experimental results show that laser shock peening effectively eliminates the residual tensile stress generated by laser polishing. The compressive residual stresses of the laser-polished samples subjected to laser shock peening with 3, 6, and 9 J energies are 114.5, −138.5, and −209.5 MPa, respectively. Moreover, the surface roughness, microhardness, and microstructure evolution of the laser-polished surface with laser shock peening are investigated.
The effects of the printing direction and UV artificial degradation on the mechanical properties using AM PolyJet technology
Authors: Matušú Martin , Blaha David , David Petr , Padovec Zdeněk , Růžička Pavel , Řezníček Jan , Růžička Milan
Published: May 2021

This study addresses differences in the material properties due to the influence of the printing direction, UV degradation and the use of differently coloured materials. The specimens were manufactured employing PolyJet technology from the Vero material (VeroBlue, VeroYellow, VeroMagenta). Subsequently, the specimens were subjected to tension and compression testing. Ageing is simulated via the exposure of the specimens to solar UVA and UVB for 15 and 30 days (the calculated daylight UV exposure for half a year and a whole year, respectively). The differences in the material properties were also determined according to the types of material. The results were then subjected to a statistical analysis.
pacto antenupcial como instrumento de planejamento sucessório face a vedação do pacta corvina
Authors: Lucachinski Jessica , Fante Cilmara Corrêa de Lima
Published: May 2021

O presente artigo sustenta uma reflexão sobre a possibilidade de o pacto antenupcial servir de instrumento do planejamento sucessório, ante a existência da vedação legal de pactos sucessórios relativos à herança de pessoa viva. O Código Civil Brasileiro consagra a mínima intervenção estatal sobre as relações familiares, dando-lhe autonomia patrimonial aos membros da entidade familiar estipularem através de Pacto antenupcial regimes matrimoniais, quanto a seus bens o que lhes aprouver. Já no âmbito sucessório a autonomia patrimonial vem albergada na possibilidade de renúncia da herança ou de legado pelo ente familiar. Diante dessas premissas, de não intervenção estatal questiona-se sobre a utilidade das regras proibitivas nos contratos antenupciais com a finalidade de planejamento sucessório, a fim de blindar o patrimônio e evitar futuros litígios. Em termos de tipo de pesquisa da qual resulta o presente texto, trata-se de uma análise com caráter qualitativo, através do método dedutivo, com o estudo e comparação de doutrinas, artigos científicos e leis. Atualmente a doutrina e jurisprudência majoritária reputa invalida a cláusula de renúncia de herança considerando a existência da vedação do pacta corvina.
Abandono afetivo inverso
Authors: Balak Juliana Gruber , Ningeliski Adriane de Oliveira
Published: May 2021

O presente artigo tem por finalidade examinar a questão do abandono afetivo inverso suportado pelos idosos. Os conflitos decorrentes da convivência familiar a qual o cidadão idoso é exposto, necessita de um estudo aprofundado para proteção mais ampla e amparo jurídico. Devido a previsão legal existente busca-se analisar a possibilidade da condenação da prole em indenização pelo dano moral sofrido pelo idoso. Utiliza-se dos diversos conceitos doutrinários quanto à responsabilidade civil, dano moral e família. O estudo decorreu principalmente de pesquisa bibliográfica, doutrinária e jurisprudencial, por meio de pesquisa qualitativa, conforme o método dedutivo, com embasamento principalmente em doutrina. Em princípio demonstra o conceito de família, sob a ótica histórica e constitucional, realçando o princípio da afetividade e da dignidade da pessoa humana, voltando-se especificamente à questão do idoso nessa relação. Após disserta-se sobre a responsabilidade civil propriamente dita, quando ocorre o abandono afetivo inverso e do consequente dano moral, que o fato enseja. Como possível conclusão, entende-se que se faz necessária uma punição mais severa à prole que transgredir os cuidados e amparos necessários para a qualidade de vida no idoso, enquanto cidadão, suporta e precisa na velhice. A jurisprudência acerca do tema é precária, tem se percebido a inclinação no sentido de amparar esse tema, inclusive com a ponderação do STJ para atribuir indenização por dano moral afetivo quando é praticado face ao ascendente.
desafio no cumprimento da medida de internação aplicada aos adolescentes autores de ato infracional
Authors: Kovalski Evelin Maiara , Ningeliski Adriane de Oliveira
Published: May 2021

O Direito transforma-se constantemente à medida das mudanças vividas pela sociedade. Com relação ao Direito da Criança e do Adolescente não poderia ser diferente. Com o passar dos anos, diversos documentos internacionais influenciaram diretamente o Direito Brasileiro e sua forma de proteger e responsabilizar os adolescentes. Exemplo disso é a Constituição Federal de 1988 e o Estatuto da Criança e do Adolescente de 1990. Com o advento desse novo sistema, adotou-se a doutrina da proteção integral, em que crianças e adolescentes passam a ser sujeitos de direito, levando em consideração que se encontram em situação peculiar de pessoas em desenvolvimento. A partir disso, surgiu a proposta de responsabilização do adolescente autor de ato infracional através da implantação de práticas pedagógicas em detrimento das medidas punitivas que anteriormente eram aplicadas. O objetivo da presente pesquisa é refletir acerca do desafio do cumprimento do caráter pedagógico e social da medida socioeducativa, especialmente com relação à medida de internação. Utilizar-se-á o método dedutivo, tendo em vista a presente pesquisa partir de um fato específico, que é o cumprimento da medida socioeducativa de internação por adolescentes que praticam ato infracional, gerando a pergunta que procurar-se-á responder, nesse sentido: se referida medida cumpre seu caráter social e educativo.
reconhecimento da família paralela como entidade familiar à luz do direito de família
Authors: Kuss Aline Hirt , Ningeliski Adriane de Oliveira
Published: May 2021

A família paralela, também denominada de família simultânea, é aquela em que um indivíduo se coloca no núcleo de formação de duas famílias distintas, de forma simultânea. Tal formação familiar existe no seio da sociedade brasileira, contudo, sem contar com qualquer segurança ou resguardo jurídico, que deveriam ser fornecidos pelo Estado, tendo em vista que a legislação vigente simplesmente ignorou essa formação familiar, sem pronunciar qualquer direito ou dever. Por conta disso, muitos indivíduos que se veem em uma situação de simultaneidade familiar estão recorrendo ao Poder Judiciário, para buscar assegurar os direitos que entendem possuir, tendo resultado em inúmeras decisões judiciais conflitantes por todo o país, pela falta de unanimidade em reconhecer, ou não, tal situação como uma entidade familiar. Assim, a simultaneidade familiar não é fruto de uma proclamação legislativa, ou seja, não é algo previsto em lei. É, porém, um fenômeno social, e que vem se revelando com maior relevância no atual momento histórico, impondo-se ao direito e, consequentemente, demandando apreensão jurídica. Nessa toada, apresenta-se este estudo, através do método dialético, buscando dialogar entre os variados conceitos de família e formas de entidades familiares, com base na Constituição Federal, com o objetivo de averiguar a possibilidade de atribuir às famílias paralelas o status de entidade familiar, reconhecida pelo Direito de Família. Ao final, percebe-se a necessidade do reconhecimento da família paralela como uma entidade familiar, em respeito aos princípios constitucionais aplicados ao Direito de Família.
condição do encarcerado no sistema prisional brasileiro
Authors: Martins Jilia Diane , Bazzanella Sandro Luiz
Published: May 2021

A pesquisa objetiva investigar em que medida o sistema carcerário brasileiro transforma os condenados em Homo Sacer, paradigma societário apresentado por Agamben, reduzindo-os a mera “Vida Nua”. Para tanto, de forma qualitativa, utiliza-se o método bibliográfico incialmente, para definir os conceitos que afetam o tema e em seguida, apresenta dados estatísticos sobre o sistema carcerário brasileiro. Assim, é possível comprovar a hipótese de que se o encarcerado possui direitos e garantias estabelecidas em lei, mas estes não são efetivados pelo Estado, então identifica-se com a condição do Homo Sacer.
Infiltração de agentes policiais
Authors: Lombardi Felipe de Almeida Cezário , Silva Rodrigo Vaz
Published: May 2021

Nos últimos anos, com os avanços nos mecanismos de obtenção de provas em organizações criminosas, muito passou-se a discutir sobre os limites de atuação de agentes policiais, sobretudo no âmbito da infiltração policial. É fato que apesar de existir uma legislação específica que versa sobre o tema (Lei 12.850/2013) ainda existe uma série de discussões sobre a punibilidade da conduta do agente e o uso de excludentes de antijuridicidade. Nesse contexto, o presente artigo tem por objetivo analisar de que forma as excludentes de ilicitude, tipicidade e culpabilidade podem ser utilizadas para justificar os delitos ou crimes cometidos por agentes policiais infiltrados em prol do êxito das investigações. A partir de uma revisão bibliográfica, evidenciou-se que os crimes praticados por agentes infiltrados devem ser avaliados com rigor e cautela, haja vista que a legislação em vigor não trata, em específico, das exceções a serem levadas em consideração no desenrolar das ações investigatórias.
revogação do direito às horas in itinere trazido pela reforma trabalhista e seu impacto na caracterização de acidente de trajeto
Authors: Deluca Ana Paula , Maciel Juliana
Published: May 2021

A presente pesquisa é explicativa e concomitantemente exploratória. Demonstrando a importância da avaliação e posição sobre as mudanças das horas in itinere, conforme a Reforma Trabalhista, Lei nº 13.467/2017 e sua atual equivalência para com os empregados. Além das referidas mudanças legislativas, faz-se o estudo do direito às horas itinerárias no contrato de trabalho antes da reforma e os princípios norteadores, como o da inalterabilidade contratual lesiva, princípio da norma mais favorável, princípio da condição mais benéfica e o princípio da proibição ao retrocesso social. Tem como pressuposto a origem das horas itinerárias e de que forma surgiram, atrelado ao seu conceito e características, até sua revogação, conjuntamente com a importância da jornada de trabalho. Apresenta também a relação do acidente de trajeto amparado como acidente de trabalho, compreendendo acerca da sua aplicação e ainda em relação às Medidas Provisórias 905/2019 e 955/2020. Por fim, tem como objetivo demonstrar se houve ou não prejuízos ao empregado em virtude da reforma trabalhista após a revogação das horas itinerárias e sua legislação do acidente de percurso. Concluindo que há supressão do direito ao recebimento das horas in itinere pela reforma trabalhista que por conseguinte, vem de encontro com o preceito legal relacionado ao acidente de trajeto, que gerou desta forma, conflito doutrinário e jurisprudencial.
Colisão entre os direitos fundamentais à vida e a liberdade religiosa quanto à transfusão de sangue
Authors: Wolf Marlides Copelli , Bueno Mariza Schuster
Published: May 2021

O presente artigo aborda a questão da colisão entre o direito à vida em relação à liberdade religiosa quanto à transfusão de sangue, mais especificamente na religião Testemunhas de Jeová, que se opõem à transfusão sanguínea mesmo com o iminente risco de vida. Os profissionais da área médica, muitas vezes se deparam com dificuldades de atuação na garantia da vida e da saúde em relação às questões de ordem religiosa, tornando assim difícil o cumprimento do Código de Ética Médica. Destaca-se que, apesar de fundamental, o direito à liberdade religiosa não deve ser analisado de forma isolada, devido à sua dependência bilateral com os direitos fundamentais, e que em caso de colisão com o direito à vida, ainda que seja dever do Estado respeitar a liberdade de convicção religiosa, a vida deve ser elevada a um patamar superior. O direito à vida é essencial, pois sem ele não há como usufruir dos outros direitos. A título de metodologia, tem-se a análise doutrinária e jurisprudencial, amparadas pelos preceitos constitucionais, utilizando-se para tanto o método dedutivo. A doutrina e a jurisprudência divergem a respeito do tema, e a solução dessa controvérsia é sopesada no caso concreto. Diante desse contexto interroga-se: o direito à vida tem prevalência sobre a liberdade religiosa? Neste sentido, o direito fundamental à vida entra em conflito com o direito fundamental à liberdade religiosa, sendo assim, necessária a ponderação para a solução eficaz da referida contenda.
inconstitucionalidade da Emenda 96/2017 frente à proteção ambiental constitucional
Authors: Beninca Natalie Bianca Alves , Diniz Thiago Antônio Nascimento Monteiro
Published: May 2021

Os maus tratos aos animais têm se tornado um tema recorrente em embates jurídicos, bem como têm se tornado objeto de apreciação do poder judiciário, tendo inclusive, julgados do Supremo Tribunal Federal quanto ao tema. Ocorre que, com a Emenda Constitucional n. 96 os maus tratos deixaram de ser considerados cruéis desde que sejam decorrentes de manifestações culturais. Diante do exposto, e tomando a vaquejada como prática considerada esportiva e cultural, fez-se uma análise de tal manifestação frente ao direito fundamental à um meio ambiente ecologicamente equilibrado e a proteção aos animais, bem como levado em consideração os julgados do Supremo Tribunal Federal quanto ao tema. Partindo disto, o presente estudo teve como problemática a seguinte pergunta: seria inconstitucional a emenda constitucional n. 96/2017? Para tanto, buscou-se descrever o que estabelece a doutrina, legislação e jurisprudência sobre a vaquejada, além de tecer considerações histórico-culturais sobre ela. Por esse motivo, foi necessário estabelecer a relação da vaquejada e seu conteúdo conforme lei e jurisprudência, analisar as ADIs 4.983, 5.728 e 5.772. Desse modo, foi utilizada a pesquisa qualitativa, com método descritivo de análise documental. Ao final do estudo, foi possível concluir pela inconstitucionalidade da emenda constitucional n. 96.
A case report of simultaneous medullary and papillary carcinoma of thyroid
Authors: Ziaolhagh Reza , Sadrizadeh Ali , Shabany Babak Peyro , Roudi Asma Ahrari
Published: May 2021

Objective. Medullary (MTC) and papillary (PTC) thyroid carcinoma are two different types of thyroid carcinoma with significant differences in origin. Their co-occurrence in a patient is a rare phenomenon. We report a patient with simultaneous presentation of both MTC and PTC.

Case presentation. A 62-year-old euthyroid woman with a cervical mass was evaluated, underwent total thyroidectomy, and neck dissection. The examination revealed a MTC large nodule as well as a small nodule of the tall cell variant of PTC, along with the concomitant cervical lymph node metastases. Subsequently, the genetic analysis showed BRAF mutations. Adjuvant treatments including radioiodine and thyroid hormone replacement therapies were performed for the patient.

Conclusions. The cooccurrence of MTC and PTC in the same patient is a rare phenomenon. The clinical manifestations and biological behavior of these cancers are completely different. Since the therapeutic strategy and prognosis are very different in these patients, accurate diagnosis of this coexistence is very important.
Extra-forebrain impact of antipsychotics indicated by c-Fos or FosB/ΔFosB expression: A minireview
Authors: Kiss Alexander , Osacka Jana
Published: May 2021

It is apparent that the c-Fos and FosB/ΔFosB immunohistochemistry has generally become a useful tool for determining the different antipsychotic (AP) drugs activities in the brain. It is also noteworthy that there are no spatial limits, while to the extent of their identification over the whole brain axis. In addition, they can be in a parallel manner utilized in the unmasking of the brain cell phenotype character activated by APs and by this way also to identify the possible brain circuits underwent to the APs action. However, up to date, the number of APs involved in the extra-striatal studies is still limited, what prevents the possibility to fully understand their extra-striatal effects as a complex as well as differentiate their extra-striatal impact in qualitative and quantitative dimensions. Actually, it is very believable that more and more anatomical/functional knowledge might bring new insights into the APs extra-striatal actions by identifying new region-specific activities of APs as well as novel cellular targets affected by APs, which might reveal more details of their possible side effects of the extra-striatal origin.
General Theory and Tools for Proving Algorithms in Nominative Data Systems
Authors: Jaszczak Adrian
Published: May 2021

In this paper we introduce some new definitions for sequences of operations and extract general theorems about properties of iterative algorithms encoded in nominative data language [20] in the Mizar system [3], [1] in order to simplify the process of proving algorithms in the future.

This paper continues verification of algorithms [10], [13], [12], [14] written in terms of simple-named complex-valued nominative data [6], [8], [18], [11], [15], [16].

The validity of the algorithm is presented in terms of semantic Floyd-Hoare triples over such data [9]. Proofs of the correctness are based on an inference system for an extended Floyd-Hoare logic [2], [4] with partial pre- and postconditions [17], [19], [7], [5].
Partial Correctness of an Algorithm Computing Lucas Sequences
Authors: Jaszczak Adrian
Published: May 2021

In this paper we define some properties about finite sequences and verify the partial correctness of an algorithm computing n-th element of Lucas sequence [23], [20] with given P and Q coefficients as well as two first elements (x and y). The algorithm is encoded in nominative data language [22] in the Mizar system [3], [1].

i := 0

s := x

b := y

c := x

while (i <> n)

c := s

s := b

ps := p*s

qc := q*c

b := ps − qc

i := i + j

return s

This paper continues verification of algorithms [10], [14], [12], [15], [13] written in terms of simple-named complex-valued nominative data [6], [8], [19], [11], [16], [17]. The validity of the algorithm is presented in terms of semantic Floyd-Hoare triples over such data [9]. Proofs of the correctness are based on an inference system for an extended Floyd-Hoare logic [2], [4] with partial pre- and post-conditions [18], [21], [7], [5].
Basic Principles for Therapeutic Relationship and Practice in Gestalt Theoretical Psychotherapy
Authors: Böhm Angelika
Published: May 2021

Gestalt Theoretical Psychotherapy, in the broader sense of the term, has developed in various forms on both sides of the Atlantic since the 1920s. Gestalt Theoretical Psychotherapy, in the narrower sense of the term, came into being in the second half of the 1970s in German-speaking countries. In Austria, it is a state-approved, independent scientific psychotherapy method since 1995, and an integrative psychotherapeutic approach based on the Gestalt theory of the Berlin School. With reference to this comprehensive, consistent, scientific theory, this article presents the basic concepts of therapeutic practice in the field of Gestalt psychotherapy. Starting from the overarching whole to the parts, the paper first examines the concept of therapeutic relationship and therapeutic attitude, and then describes the basic principles of the practical design of the therapeutic process.
Gestalt Theoretical Psychotherapy – A Clinical Example
Authors: Fuchs Thomas
Published: May 2021

The case of an anorectic patient is presented to demonstrate how well-known symptomatic phenomena such as a supposedly distorted body perception can be understood. Further theoretical suggestions are made to explain the motive to starve, without making complicated psychodynamic assumptions. To do so, genuine gestalttheoretical concepts such as ‘centring’ and ‘reference system’ are used. This leads to hints for a temporarily perception-focused formation of the therapeutic relationship.
Effect of soil textural characteristics on longitudinal dispersion in saturated porous media
Authors: Mahmoodlu Mojtaba G. , Raoof Amir , van Genuchten Martinus Th.
Published: May 2021

This study focuses on the effects of soil textural heterogeneity on longitudinal dispersion under saturation conditions. A series of solute transport experiments were carried out using saturated soil columns packed with two filter sands and two mixtures of these sands, having d50
values of 95, 324, 402, and 480 µm, subjected to four different steady flow rates. Values of the dispersion coefficient (D) were estimated from observed in-situ distributions of calcium chlo-ride, injected as a short nonreactive tracer pulse, at four different locations (11, 18, 25, 36 cm). Analyses of the observed distributions in terms of the standard advection-dispersion equation (ADE) showed that D increased nonlinearly with travel distance and higher Peclet numbers+. The dispersion coefficient of sand sample S1 with its largest average particle size (d
50) was more affected by the average pore-water velocity than sample S4 having the smallest d
50. Results revealed that for a constant velocity, D values of sample S1 were much higher than those of sample S4, which had the smallest d
50. A correlation matrix of parameters controlling the dispersion coefficient showed a relatively strong positive relationship between D and the Peclet number. In contrast, almost no correlation was evident between D and porosity as well as grain size. The results obtained with the four sandy matrices were consistent and proved that the dispersion coefficient depends mainly on the particle size.