bluuebunny/crossref_metadata_2025 huggingface dataset:
The use of radiofrequency in equine orthopedic surgery
Authors: Barton Charlotte K. , Goodrich Laurie R.
Published: April 2023

The use of radiofrequency energy (RFE) has become increasingly popular in equine orthopedic surgery in recent years, particularly for the debridement of cartilage lesions and soft tissue resection. However, despite considerable advancements in the technology, the safety and efficacy of RFE have continued to be questioned. While studies investigating the use of RFE for chondroplasty in the equine population are lacking, there is an abundance of research studies in the human literature assessing its effect on healthy chondrocytes, and researchers are seeking to develop guidelines to minimize collateral damage. This review article provides a concise and thorough summary of the current use of RFE in equine orthopedics, in addition to discussing the recent evidence surrounding its use for chondroplasty in both the human and equine populations.
Successful correction of stenotic nares using combined Alar Fold Lift-Up and Sulcus Pull-Down Techniques in brachycephalic cats: 8 cases (2017–2022)
Authors: Pavletic Michael M. , Trout Nicholas J.
Published: April 2023

OBJECTIVE

Describe surgical guidelines for a new technique to correct stenotic nares in brachycephalic cats.

ANIMALS

8 client-owned brachycephalic cats with stenotic nares between April 2017 and July 2022.

PROCEDURES

8 brachycephalic cats with severe stenotic nares presented to the Angell Animal Medical Center with the patient age ranging from 2 years to 9 years of age. Surgical correction was performed on each cat with the combined use of the “Alar Fold Lift-Up” and “Sulcus Pull-Down” techniques.

RESULTS

Successful correction of the stenotic nares was achieved, enabling each cat to breathe normally.

CLINICAL RELEVANCE

The combined use of the “Alar Fold Lift-Up” and “Sulcus Pull-Down” techniques is simple to perform on an outpatient basis. Surgery is restricted to the adjacent skin and does not require the surgical alteration of the external nose or nares. Long-term follow-up indicates the procedure is effective in improving nasal breathing in each cat.
d,l-Methionine in combination with amoxicillin–clavulanic acid successfully dissolves spontaneously occurring infection-induced struvite urocystoliths in dogs: a pilot study
Authors: Harris Amber S. M. , Bartges Joseph W. , Moyers Tamberlyn D.
Published: April 2023

OBJECTIVE

To determine the efficacy and safety of a urinary acidifier (d,l-methionine [Methio-Form]) and an antimicrobial agent (amoxicillin–clavulanic acid [Clavamox]) without changing diet for dissolving infection-induced struvite urocystoliths in dogs.

ANIMALS

14 dogs were recruited for this prospective study; 11 completed it and 3 dogs withdrew due to inability of the owners to administer the treatment (n = 2) or refusal of treatment by the dog (1).

PROCEDURES

All dogs were administered d,l-methionine (approx initial dose of 75 mg/kg, PO, q 12 h) and amoxicillin–clavulanic acid (22 mg/kg, PO, q 12 h) based on urine culture and sensitivity. Urine pH, urinalysis, urine culture, venous blood gas and serum biochemical analysis, and lateral survey abdominal radiographic images were evaluated initially and every 4 weeks until urolith dissolution (success) or lack of change in size and/or shape of urocystoliths on 2 consecutive reevaluation points (failure) occurred.

RESULTS

Uroliths dissolved in 8 of 11 dogs in a median of 2 months (range, 1 to 4 months) with a final effective dosage of d,l-methionine of approximately 100 mg/kg, PO, every 12 hours. In 3 dogs, uroliths failed to dissolve and were removed surgically; they contained variable amounts of calcium oxalate. No adverse events occurred.

CLINICAL RELEVANCE

Infection-induced struvite urolithiasis is 1 of the 2 most common minerals occurring in canine uroliths. Results of this study supported the use of d,l-methionine and amoxicillin–clavulanic acid without changing diet for dissolution of infection-induced struvite urocystoliths in dogs.
Experiences of International Students in Latvia: The Case of India and Germany
Authors: Apsite-Berina Elina , Robate Liga Daniela , Berzins Maris , Krisjane Zaiga
Published: April 2023

This paper examines the internationalisation processes in the higher education sector in Latvia and explores the motives of international students to study in Latvia, their experience and their plans. The study uses a quantitative data collection method – a survey – the results of which allow us to judge the main trends of internationalisation processes in Latvia. The differences between different groups were investigated, highlighting the countries with the most respondents – India and Germany, and comparing them with each other and with students from other countries. The results show that there are substantial differences between the groups. For German students, Latvia was more of a second option when they failed to get into their preferred university in their home country or elsewhere. They chose to study in Latvia mainly because of the university’s study programmes. At the same time, students from India were also interested in factors such as culture, the Baltic region and the attractiveness of Riga.
Expert Teachers’ Perceptions of Their Students’ Environmental Literacy and the Practice of Environmental Education
Authors: Huoponen Anssi
Published: April 2023

Effective environmental education (EE) is urgent as climate change and environmental degradation are proceeding. More theoretical models to enhance the effectiveness of environmental education are constantly presented, but a comprehensive view from teachers’ perspectives is absent. This paper presents unique results from expert ENO Schoolnet Association’s (ENO) expert EE teacher group interviews from the World Summit of Students for Climate Event (WSSC). These educators represent over 40 nations. The group interviews explore the teachers’ perceptions of their students’ environmental literacy and teaching of EE. The data were analyzed with content analysis. The results point out that these expert EE teachers feel that most students fail to achieve operational environmental literacy. This paper examines the potential school-related and student-related barriers preventing this operational literacy. Furthermore, the EE provided by the teachers usually lacks behavioral literacy methods. At the same time, the teachers feel that these methods should be emphasized to ensure the effectiveness of EE. In the future, it would be useful to study environmental clubs’ potential to overcome some of the barriers and promote pro-environmental actions.
Evaluation of novel beverage formulations for hydration enhancement in humans
Authors: Tinsley Grant M. , Siedler Madelin R. , Rodriguez Christian , Harty Patrick S. , Stratton Matthew T. , White Sarah J. , Keith Dale S. , Green Jacob J. , Boykin Jake R. , Williams Abegale D. , DeHaven Brielle , Brojanac Alexandra , Tinoco Ethan
Published: April 2023

This study evaluated the influence of novel beverage formulations on bioimpedance- and urine-based hydration markers. Thirty young healthy adults (n=16 females, n=14 males; age: 23.2±3.7 years; BMI: 24.3±3.3 kg/m2) participated in a randomized, double-blind, placebo-controlled, crossover study. Participants completed three conditions with baseline bioimpedance, urine, and body mass assessments, followed by ingestion of one liter of a test beverage over a 30-minute period. The three beverages were: active hydration formulation in still (AFstill) or sparkling (AFspark) water and a still water control. The active formulations were identical in concentrations of alpha-cyclodextrin and complexing agents. Following beverage ingestion, bioimpedance assessments were performed every 15 minutes for two hours, followed by final urinary and body mass assessments. The primary bioimpedance outcomes were phase angle at 50 kHz, resistance of the extra-cellular compartment (R0), and resistance of the intracellular compartment (Ri). Data were analyzed using linear mixed effects models, Friedman tests, and Wilcoxon tests. Statistically significant changes in phase angle values were observed at 30 (p=0.004) and 45 minutes (p=0.024) following the initiation of beverage ingestion in the AFstill condition as compared to the reference model (i.e., control condition at baseline). Although differences between conditions were not statistically significant at later time points, the data were consistent with AFstill having greater elevations in phase angle throughout the monitoring period. At the 30-minute time point only, statistically significant differences in R0for AFspark (p<0.001) and in Ri for AFstill (p=0.008) were observed. When averaged across post-ingestion time points, there was a trend (p=0.08) for Ri differences between conditions. The net fluid balance was greater than zero, indicating retention of ingested fluid, for AFstill (p=0.02) and control (p=0.03), with a trend for AFspark (p=0.06). In conclusion, an active formulation containing alpha-cyclodextrin in still water demonstrated potential benefits for enhancing hydration markers in humans.
Equivalence in Translation. Translation Studies as an Interdiscipline
Authors: Oneţ Alina-Elena , Ciocoi-Pop Ana-Blanca
Published: April 2023

The phenomenon of equivalence has been at the centre of focus for numerous researchers during the past decades, especially in the field of translation studies, equivalence being one of the key concepts of translation theory. However, the concept has also come to be regarded as highly elusive and oftentimes difficult to define and achieve. In addition to this, translation itself is regarded as a multifaceted discipline, which has always been looked upon in various diverse manners. Even though these definitions vary greatly, they do have some common denominators: the reference to the two languages involved in the translation process (source language and target language) and the creation of equivalence between the original and the translated text, in order to preserve the original’s characteristics. In the present paper we attempt to shed light on some of the characteristics of equivalence in translation, and by resorting to a series of theoretical considerations, as well as practical examples, demonstrate how equivalence is sometimes challenging to achieve.
Laser Safety in Army Education
Authors: Lazov Lyubomir , Padarev Nikolay Iliyanov
Published: April 2023

Studies have been made on the development of military science and it has been established that for the modernization of the army and the defense industry it is necessary to develop and search for new innovative technological solutions in the field of laser technology and photonics. According to the trends in the use of laser technologies for military applications, the need to acquire knowledge in the field of “Laser Safety” has also been proven. The report substantiates the need to train cadets and students in a military university. A curriculum on “Laser Safety” is proposed and what knowledge and skills future officers should acquire are indicated.
Features of laparoscopic and conventional decompression of the сeliac trunk
Authors: Bagnenko S. F. , Vasilevsky D. I. , Ignashov A. M. , Кнamid Z. M. , Puzanov S. Yu. , Rumyantsev I. P. , Balandov S. G. , Morozov A. N. , Suprunovich A. A.
Published: April 2023

The OBJECTIVE was to study the efficacy and safety of laparoscopic decompression of the celiac trunk.

METHODS AND MATERIALS. A comparative analysis of the results of laparoscopic (30 patients) and conventional decompression of the celiac trunk (50 patients) was carried out. All patients were operated on between September 2018 and July 2021.

RESULTS. Intraoperative bleeding during laparoscopic decompression of the celiac trunk, which required conversion of access to laparotomy and vascular suture, was noted in 2 (6.7 %) cases. With conventional access, there were no such complications. The average duration of laparoscopic decompression of the celiac trunk was 107 minutes, from conventional access – 150 minutes. The average length of hospital stay after laparoscopic intervention was 4 days, after the traditional one – 7 days. Long-term results of treatment over a period of more than 6 months were evaluated in 28 patients who underwent laparoscopic decompression of the celiac trunk and 45 people who underwent conventional decompression. Ultrasound examination in all cases stated the return of linear and velocity parameters of blood flow in the celiac trunk to normal. complete relief of the clinical manifestations of the disease was achieved in 24 (85.7 %) patients after laparoscopic and in 39 (86.7 %) after traditional intervention.

CONCLUSION. Laparoscopic decompression of the celiac trunk is an effective method of surgical treatment of the syndrome of compression of the celiac trunk, but there are risks of vascular damage. The long-term results of laparoscopic and open decompression of the celiac trunk are comparable.
Combined use of techniques of fistula ligation in the intersphincteric space and laser destruction of the fistula tract in patients with chronic paraproctitis
Authors: Gor I. V. , Nedozimovanyi A. I. , Popov D. E.
Published: April 2023

The OBJECTIVE was to improve the treatment outcomes of patients with chronic paraproctitis using the combination of minimally invasive techniques.

METHODS AND MATERIALS. The treatment outcomes of 170 patients with transsphincteric anal fistulas of cryptoglandular origin were analyzed. The duration of the disease in both groups varied within 2–34 months. The main group included 85 patients operated with a combined minimally invasive method (laser destruction of the fistulous tract with subsequent ligation and its ligation in the intersphincter space), in the control group, 85 patients underwent LIFT procedure.

RESULTS. Median follow-up for patients in the main group was 13 months, in the control group – 24 months. In the main group, relapses were registered in 10 patients (11.8 %), in the control group – in 22 patients (25.9 %). The average time for the formation of relapses in the main and control groups was 4 months. There was no clinically significant violation of the function of the rectal obturator in both groups.

CONCLUSION. The ability to combine the LIFT procedure and laser destruction of the fistulous tract allows to achieve fewer relapses compared to the isolated use of the LIFT technique in patients with transsphincteric anal fistulas.
Results of laparoscopic Heller esophagocardiomyotomy with Dor fundoplication in patients with stages 3 and 4 of the esophageal achalasia
Authors: Tseimakh E. A. , Gankov V. A. , Bagdasarian G. I. , Andreasyan A. R. , Maslikova S. A.
Published: April 2023

INTRODUCTION. The choice of a treatment method in patients with stages 3–4 of the esophageal achalasia remains an actual topic.

The OBJECTIVE was to evaluate the long-term results of Heller esophagocardiomyotomy with Dor hemiesophagofundoplication at stages 3–4 of the esophageal achalasia by comparing the results of patient survey with data of instrumental methods of diagnosis of esophageal function.

METHODS AND MATERIALS. The results of the operation were analyzed in 67 patients, including 35 patients with stage 3 and 32 patients with stage 4 of the disease. The period of postoperative follow-up was 1–5 years. The results of X-ray examination of the esophagus and stomach, esophageal manometry, 24-hour pH-metry and the data of the Eckardt and GIGLI scale questionnaires were evaluated.

RESULTS. The data of X-ray examination of the esophagus and stomach, in the long-term period, showed a complete restoration of the esophagus evacuation function in all patients (p=0.001), according to manometric data, a significant decrease in the tone of the lower esophageal sphincter in all patients to normal values (p=0,001) was revealed, esophageal atony was noted in three patients with stage 4 of the disease. Pathological gastroesophageal reflux before and after surgery was not registered by pH-metry, the De Meester index was within the normal range in all groups (less than 14.72). Dysphagia in the long-term period decreased in all patients. Long-term results on the Eckardt scale in patients with stage 3 improved by 83.5 %, with stage 4 by 78.3 % (p=0.001), according to the GIGLI questionnaire, patients with stage 3 scored 83.5 %, with stage 4 by 78.3 % more than before surgery.

CONCLUSION. Laparoscopic Heller esophagocardiomyotomy with Dor fundoplication reduces symptoms of the disease in patients with stages 3–4 of the esophageal achalasia, increases the gastrointestinal index of quality of life, which makes it advisable to perform organ-preserving surgery at stage 4 of the disease.
Novel Heterozygous Sequence Variant in the HOXD13 Gene Underlie Non-syndromic Syndactyly
Authors: Abbas Safdar , Ahmad Farooq , Kanwal Misbah , Sultan Annum , Said Gulab , Umair Muhammad
Published: April 2023

Background: The term "Syndactyly" referred to an inherited deformity of the hand or foot marked by persistence of the webbing between adjacent digits that are more or less completely attached and mostly inherited in an autosomal dominant manner. Pathogenic variants in the HOXD13 (Homeobox D13) gene, located on chromosome 2q31.1, have been associated with syndactyly type 5, brachydactyly type D, E and synpolydactyly type 1 phenotypes.
Objectives: A Pakistani inbreed was recruited from the remote area of the country was added in the study and aimed to clinically and genetically characterize the syndactyly as marked abnormal feature observed.
Methodology: Whole exome sequencing coupled with Sanger sequencing was carried out to uncover the disease associated variant/s followed by 3D protein modeling to check variant related effect on protein level.
Results: WES data analysis revealed a novel-HOXD13 gene missense variant (c.969G>T; p.Trp323Cys) that might explain the disease phenogenesis. 3D protein modeling of the normal and mutant protein predicated high level changes that might compromise the ultimate function of the protein.
Conclusion: Our findings extend the mutation spectrum of HOXD13 gene and also provided additional evidence that HOXD13 play an important role in limbs development.
التقييد التشريعي لحرية التعبير عن الرأي - التشريع المعلوماتي انموذجاً
Authors: Thamer Mustafa Jwan , Khedher Ahmad Majeed
Published: April 2023

اقتصر القانون الجنائي في البداية على جرائم كالقتل والسرقة التي ألفها الناس ضمن محيطهم الاجتماعي، وانتقل إلى محيط أوسع بتطور الجماعة واحتياجاتها وتعقد وسائلها في الحصول عليها، وتركز سكانها، وتداخل علاقاتهم وتشابكها وتنوع صورها، وتزايد فرصهم في النفاذ إلى الحقائق العلمية التي على ضوئها تتنوع اشكال الجريمة وأدواتها وطرق إخفائها. ومن هنا  تولدت الحاجة لمعايير قانونية متوازنة تضبط إيقاع تلك الجرائم وطرقها، والتي من ابرزها الجرائم المتعلقة بحرية التعبير عن الرأي  باستخدام الفضاء السيبراني. إذ لا محل للاعتقاد بأن مدلول التنظيم يتنافى مع الحرية، ذلك أن تحقيق تنظيم اجتماعي معين يفترض وجوب استخدام الحرية. وإذا كان المشرع بشكل عام يتدخل واضعاً القاعدة القانونية المنظمة للحرية فهو لا يجعلها ملزمة دائماً، بل يسمح كثيراً للحرية بأن تتفق على ما يُخالفها، ومن ثم لا تكون القاعدة القانونية حينئذ إلا مكملة أو متمتمه. ومن الطبيعي أيضاً أن الحرية لن تكون مطلقة بلا حدود ولا رقابة، إذ أن ذلك من شأنه أن يُفضي إلى إنكار مبدأ التنظيم الاجتماعي وجدواه، وإذا كان على القانون أن يكفل التعبير عن الحرية الكاملة أو على الأقل عن الحرية الكافية، إلا أنه يجب مراعاة الجوانب التنظيمية التي تُكيف التجاوب مع مفهوم الحرية. فالواقع أنه متى تعارضت المصالح الخاصة وتضاربت فإنها لا توصل إلى تحقيق الصالح المشترك، بل تُوجد الشقاق والصراع، مما يقتضي مواجهة الاساءات المترتبة بقسط من التدخل التشريعي ضمن مجموعة من المعايير المتوازنة.
Correlación de los estilos de vida con la obesidad y el sobrepeso en adultos
Authors: Duran Santiago Ana Cristina , Santes-Bastián María del Carmen , Martínez-Díaz Nazaria
Published: April 2023

Objetivo. Analizar la correlación de los estilos de vida con la obesidad y el sobrepeso en adultos adscritos a un Centro de Salud de Veracruz, en el periodo agosto 2021- julio 2022. Metodología. La investigación fue de tipo analítico y transversal, conformada por una población de 108 adultos, mediante un muestreo no probabilístico por conveniencia. Resultados. Se reporta que el 100% de los pacientes tienen un estilo de vida no saludable, las dimensiones con mayor porcentaje fueron, responsabilidad en salud (100%), ejercicio (98%), manejo del estrés (98%) y nutrición (94%). La población encuestada presentó conductas no saludables, encontrando una correlación significativa entre los estilos de vida con la obesidad y el sobrepeso (pr=0.000), así como en las dimensiones de nutrición (pr=0.004), responsabilidad en salud (pr=0.002) y manejo del estrés (pr=0.001). Conclusión. Se encontró correlación significativa entre los estilos de vida con la obesidad y el sobrepeso en adultos.
Saberes y experiencias comunitarias locales de los Objetivos de Desarrollo Sostenible
Authors: Becerra Zavala María De Lourdes
Published: April 2023

Se presentan resultados del diagnóstico sobre patrimonios y experiencias comunitarias en relación con algunos Objetivos de Desarrollo Sostenible (ODS) de incidencia a nivel local, para la identificación de algunas dimensiones socioculturales de los desafíos y logros en la implementación local de la Agenda 2030. En el marco de la metodología horizontal, se recuperó la información de septiembre 2021 a julio 2022, a partir del Seminario Interdisciplinario “Saberes comunitarios ODS e indicadores de desarrollo local sostenibles en México”, fuentes de información oficiales, así como entrevistas a líderes comunitarios y académicos con actividades de base comunitaria. Se caracterizan patrimonios ubicados en 3 municipios mexicanos, identificando algunas líneas de acción de base comunitaria para el fortalecimiento y sostenibilidad de proyectos locales ODS.
Entre paisajes cafetaleros y tradición
Authors: Xotlanihua Damián
Published: April 2023

En los territorios cafetaleros de México habitan 32 grupos étnicos que han resistido a las crisis económicas y ambientales producto de la liberación de cuotas en 1988 y la enfermedad de la roya en 2012. La población de estudio corresponde a una de estas regiones, es el grupo étnico nahua de Tlecuaxco, ubicado en las altas montañas en la Sierra de Zongolica, Veracruz. El objetivo del manuscrito es analizar la resistencia y adaptación de un pueblo originario frente a las crisis económicas y ambientales que afectan a la producción de café. El análisis se realiza a partir de los conceptos teóricos: geografía humana, paisaje agrario y tradición, en dialogo con datos etnográficos provenientes de una metodología horizontal en la que se emplearon métodos cualitativo y cuantitativo a partir de técnicas y herramientas etnográficas: diario de campo, entrevistas, encuesta, recorridos a nivel parcela, lectura de paisaje y observación directa y participativa.
Los resultados de la investigación demuestran las dificultades (relaciones de poder internas y mercado del café neoliberal) las alternativas (redes de comercialización en circuitos cortos) y las decisiones (trabajar la agricultura o migrar) que tienen las familias cafetaleras para adaptarse y resistir a las crisis económicas y ambientales en la producción de café. La limitación de esta investigación es que solo hace referencia a un estudio de caso; no obstante, la originalidad y el valor del trabajo radican en demostrar una estrategia de resistencia socioambiental. En las conclusiones se evidencia la importancia de la conservación socioambiental del paisaje cafetalero y de las tradiciones agrícolas de pueblos originarios como parte de preservación de los patrimonios bioculturales.
Potentially toxic element contamination and risk assessment of borehole water within a landfill in the Nnewi metropolis
Authors: Aralu Chiedozie C. , Okoye Patrice A. C. , Abugu Hillary O. , Eze Victor C. , Chukwuemeka-Okorie Helen O.
Published: April 2023

Borehole water has been used as a vital source of water for many communities. The pollution of these boreholes by potentially toxic elements using unlined solid waste dumpsites has posed a significant risk to the populace living around the dumpsite. This study investigates the environmental impact of potentially toxic elements on borehole water within the vicinity of an unlined dumpsite in the Nnewi metropolis. The upstream and downstream samples (16 each) were collected in wet and dry seasons. The potentially toxic elements analysis wasperformed using the methods of the American Public Health Association (APHA) under the required conditions. The quality of the boreholes was assessed using the World Health Organisation (WHO) acceptable limits for drinking water. The risk assessment was estimated for carcinogenic and non-carcinogenic risks using ingestion and dermal routes. The results show that the borehole water wascontaminated with potentially toxic elements through leachate infiltration, which exceeded the WHO permissible limits for drinking water at both locations and seasons. The upstream borehole samples were more contaminated than the downstream samples for both seasons, due to their proximity to the pollution source. The hazard indices of the ingestion and dermal routes showed that the borehole water poses serious cancer and non-cancer health risks for both locations. The results revealed that children are more susceptible to cancer and non-carcinogenic health threats than adults for both locations and seasons. The pollution indices of borehole water for wet season (9.028 and 5.728) and dry season (7.107 and 5.328) for upstream and downstream samples respectively, were polluted and the pollution was higher in the wet season. The borehole water samples were unsuitable for drinking water and should be treated before use.
DESENVOLVIMENTO DE HABILIDADES DE CONSCIÊNCIA FONOLÓGICA EM CRIANÇAS ENTRE 04 E 06 ANOS DE IDADE
Authors: Nery Stefane Cristine Silva
Published: April 2023

Esta pesquisa abordou como tema o Desenvolvimento de habilidades de consciência fonológica em crianças entre 04 e 06 anos de idade, e foi orientada pela seguinte problemática: As crianças de idade entre quatro e seis anos apresentam habilidades de consciência fonológica em relação aos sons iniciais e as rimas? Mediante a essa problemática a pesquisa possuiu como objetivo geral o de analisar a presença de habilidades de consciência fonológica em crianças entre 04 e 06 anos de idade. Para tanto, centrando-se numa abordagem qualitativa teve-se como lócus escolas, residências e outros locais situados na cidade de Montes Claros/MG. Para coletar as informações foi utilizada a entrevista, a qual foi desenvolvida com 40 crianças. Como aporte teórico foram utilizados autores tais como Lemle(2009), Ferreiro e Teberosky (1979), Morais (2016), dentre outros. Com a realização da pesquisa, conseguiu-se alcançar o objetivo proposto, sendo possível perceber que 37,5% das crianças apresentavam habilidades de consciência fonológica no nível dos sons iniciais, e 50% não teriam desenvolvido esta habilidade. Ainda constatou-se que 22,5% apresentavam habilidades de consciência fonológica no nível das rimas, e 67,5% revelaram dificuldades em fornecer respostas considerando os sons finais das palavras.
AS TECNOLOGIAS DIGITAIS NA PRÁTICA DOCENTE: EXPLORANDO A CONTEXTUALIZAÇÃO EM QUESTÕES DO EXAME NACIONAL DO ENSINO MÉDIO
Authors: Kleemann Robson , Machado Celiane Costa
Published: April 2023

Este trabalho tem por objetivo discutir o planejamento docente a partir de questões do Exame Nacional do Ensino Médio (ENEM), evidenciando o uso das tecnologias digitais no contexto da sala de aula. Apresenta-se uma proposta pedagógica utilizando-se de uma questão do ENEM como princípio de contextualização, direcionando à resolução e explorando conceitos diversos. Para isso, evidencia-se o uso das tecnologias digitais, mais em específico do software GeoGebra, na construção de Objetos Virtuais de Aprendizagem (OVA), objetivando facilitar, enriquecer e diversificar a prática docente. O foco principal não consiste em obter a resposta correta para a questão, mas sim explorar possíveis direcionamentos que podem ser seguidos por professores em sua prática, investigando uma situação-problema e explorando diversos conceitos matemáticos presentes no contexto.
OS ESTUDOS SOBRE EDUCAÇÃO DE SURDOS E A PERSPECTIVA TEÓRICA DA LINGUÍSTICA SISTÊMICO-FUNCIONAL: UMA REVISÃO DE LITERATURA NO PERÍODO DE 2012 A 2022
Authors: Da Cunha Aldeci Fernandes , Mendes Wellington Vieira
Published: April 2023

A história da pessoa com surdez, foi marcada por momentos de exclusão e de estigmas, sendo muitas vezes tratadas como pessoas doentes, consideradas como seres incapazes de viver em sociedade. Assim, a sua trajetória de escolarização, também foi assinalada por um processo de exclusão, em especial, no que se refere a acessibilidade linguística. Nesse sentido, este artigo apresenta um estudo de revisão acerca das pesquisas realizadas sobre a educação de surdos e a perspectiva teórica da Linguística sistêmico-funcional (LSF). Para tanto, tem como objetivo identificar pesquisas produzidas no período de 2012 a 2022 no campo da Educação de surdos permeadas pelos estudos da linguística sistêmico funcional. Como discussão teórica nos ancoramos nos trabalhos desenvolvidos no campo da abordagem da LSF, que ver a língua(gem) como um sistema sociossemiótico, e, em relação a Educação de Surdos, buscamos uma reflexão nos estudos desenvolvidos por Pereira (2011), Damázio (2007), além de outros, de modo a construirmos uma reflexão acerca do objeto em estudo. Para a realização da pesquisa, fizemos uso da abordagem qualitativa, por meio da busca de informações junto ao banco de periódicos da Capes e da Biblioteca Digital Brasileira de Teses e Dissertações, com vista a identificar as pesquisa realizadas no campo do objeto em discussão. Os resultados revelam que a área da linguística tem manifestado interesse no campo dos estudos voltados para a acessibilidade linguística, em especial, em relação ao processo de aquisição/desenvolvimento da língua(gem), a partir da perspectiva teórica da LSF, o que aponta sobre as contribuições das teorias linguísticas, aqui em especial, a LSF, para a inclusão do estudante com surdez em seu processo de escolarização. Com o trabalho, percebemos, que as discussões em torno da inclusão da pessoa com deficiência, também se torna questão de interesse das outras áreas de conhecimento, cada uma propondo uma reflexão teórica-metodológica e epistemológica a partir de seu campo de atuação.
A PESSOA COM DEFICIÊNCIA INTELECTUAL E INSERÇÃO PROFISSIONAL: A PERCEPÇÃO DA FAMÍLIA
Authors: Alves Ana Paula Ribeiro , Da Silva Nilson Rogério
Published: April 2023

Estudos têm demonstrado barreiras em diferentes âmbitos que impedem a participação de pessoas com deficiencia intelectual no mercado de trabalho. Justificativas pautadas em concepção capacitista como imprevisibilidade emocional e comportamental, incapacidade para aprender e desenvolver qualquer atividade, são atribuídas à pessoa com deficiência intelectual para que permaneça à margem do trabalho. Compreendido como atividade vital que promove o desenvolvimento humano do homem, o trabalho se constitui ainda em direito garantido por documentos e Leis que asseguram adaptações e reservas de vagas, na tentativa de superação de barreiras estruturais e atititudinais. Neste sentido, neste estudo objetivou-se identificar quais fatores contribuíram para a inserção profissional de uma pessoa com deficiência intelectual, a partir da percepção da família. Investigou-se para além das limitações, os aspectos que foram positivos, para o ingresso, permanência e progressão no mercado formal de trabalho. Nesta perspectiva, utilizamos a entrevista semiestruturada com a pessoa mais próxima de Laura para que relatasse o que em sua concepção contribuiu para a entrada no mercado de trabalho. Os dados coletados foram analisados segundo a abordagem de análise temática e os resultados revelaram que a escola não se eximiu do papel quando por meio da mediação oportunizou a apropriação dos bens culturais da humanidade e a construção de conceitos como leitura, escrita, cálculos, em constante atititude crítica, reflexiva e investigativa, habilidades imprescindíveis para a sua atual função laboral. Neste sentido, os cursos profissionalizantes realizados foram adaptados às suas necessidades, o que propiciou a construção de saberes condizentes com a realidade do mercado de trabalho e permitiu o ingresso e progressão. A família contribuiu de forma significativa para a escolarização, autonomia, indepência, empoderamento, ingresso e permanência no trabalho, demonstrando que as possibilidades são ampliadas e se tornam realidade quando contam com o apoio e participação de forma efetiva dos familiares, uma vez que acreditam e ofertam aporte ás demandas necessárias. Concluiu-se que quando diferentes instâncias como a escola, serviços de saúde, empresas, família e legislação, trabalharem em colaboração, se tornará uma realidade possível a inserção laboral da pessoa com deficiência intelectual e para além, o seu desenvolvimento humano pelo e no trabalho.
NEGÓCIOS JURÍDICOS PROCESSUAIS SOBRE TUTELA PROVISÓRIA
Authors: Magnusson Leonardo Peteno , Ferreira Jussara Suzi Assis Borges Nasser
Published: April 2023

: As convenções processuais atuam sobre a repartição dos poderes, faculdades e deveres dos sujeitos processuais, assim como do procedimento propriamente dito. A amplitude da autorregulação das partes na construção das relações e situações processuais e do procedimento se encontram o marco divisório entre os direitos das partes e os poderes do juiz. Nesse ensejo, o objetivo do presente artigo é analisar a possibilidade de as partes disporem por negócio jurídico processual acerca da concessão de tutela provisória, sem ouvir a parte contrária, pelo juiz. A pesquisa propõe analisar doutrinariamente o tema, a partir da revisão de bibliografia e documentos compreendidos na problemática, mediante a apreciação das premissas e dedução das conclusões a partir do método dedutivo. Com efeito, perfaz que o formalismo processual, enquanto modelo legal de divisão do trabalho no processo, partindo da perspectiva de processo enquanto instituição de garantia, que equilibra o conjunto de prerrogativas das partes e do juiz. Ademais, compreende os negócios jurídicos processuais como manifestação de dimensão processual do direito fundamental da liberdade, consistente na autorregulação das partes. Por seu turno, arremata os limites dos negócios jurídicos processuais como exigência de preservação de princípios e garantias constitucionais. Outrossim, concebe a tutela provisória enquanto instituto que equaciona o binômio segurança-rapidez, mas especificamente condicionado aos requisitos previstos pela lei, cuja apreciação compete exclusivamente ao juiz. Conclui, por derradeiro, pela impossibilidade de as partes disporem, por convenções processuais atípicas, dos poderes do juiz de analisar a presença (ou não) dos requisitos e a efetiva concessão ou denegação de tutelas sumárias.
Uma análise da dor do membro fantasma
Authors: Ferreira Thomaz Mota Cabo , Bullos Bernardo Silva , Costa Ana Clara Martins da , Silva Thales Figueredo e , Ferreira Igor Azevedo , Marins Amanda Souza , Siqueira Emílio Conceição de
Published: April 2023

Objetivo: Analisar as características da dor do membro fantasma (DMF). Revisão bibliográfica: A DMF é uma condição debilitante caracterizada por sensações dolorosas na parte ausente do membro amputado. A  DMF ocorre em até 85% dos amputados, tornando-se a condição de dor crônica mais comum em pessoas que sofreram amputações de membros. Múltiplas teorias foram propostas para explicar o mecanismo subjacente da DMF, sendo a reorganização cortical a mais comum. Existem dois picos de aparecimento da DMF, sendo um até a primeira semana de amputação e o outro com um ano com sensações dolorosas variando entre aguda, tiro, queimação, latejante, esfaqueamento e dor. Considerações finais: A dor do membro fantasma está associada a sofrimento pessoal, interferência nas atividades diárias gerais, incapacidade e redução da qualidade de vida relacionada à saúde. Nesse contexto, torna-se essencial o reconhecimento e tratamento adequado desta condição, visando a melhora da qualidade de vida. Na atualidade, a terpêutica da DMF é feita através de mecanismos farmacológicos como a gabapentina, morfina, cetamina e dextrometorfano e tratamentos não farmacológicos como a terapia dos espelhos.
Expiratory Aerosol pH is a Driver of the Persistence of Airborne Influenza A Virus
Authors: Schaub Aline
Published: April 2023

To mitigate the spread of a viral disease, it is crucial to understand the factors that influence airborne virus transmission. However, the micro-environment to which the virus is exposed in expiratory aerosol particles is highly complex. The relative humidity, the aerosol particle size and composition, and the air composition affect virus infectivity by modulating the salt and organic concentrations within the particle, as well as the phase state. A parameter that has been overlooked is the aerosol pH. Several viruses are sensitive to acidic pH; for example, the inactivation of influenza A virus becomes very fast at pH 5.5 and below, a threshold that is quickly reached in an expiratory aerosol particle exhaled in a typical indoor environment. Therefore, aerosol acidity plays a significant role in controlling the persistence of airborne, acid-sensitive viruses such as influenza virus, and aerosol pH control could be applied to limit the risk of airborne virus transmission.
New Frontiers in Alkali-Metal Nickelates
Authors: Borys Andryj M. , Hevia Eva
Published: April 2023

Recent advances in heterobimetallic chemistry have revealed the potential for mixed-metal systems to facilitate reactions that are unattainable with their single-metal components. This perspective explores the pairing of nickel(0) complexes with organo-alkali-metal reagents, which yield highly reactive alkali-metal nickelates. These previously underexplored systems have re-emerged as a promising area of research, with recent studies uncovering their unique bonding and structural motifs. Furthermore, the discovery of nickelates as potential intermediates in cross-coupling reactions has provided the foundation for the development and mechanistic understanding of stoichiometric and catalytictransformations.
Mechanistic Views on First-row Earth-Abundant Transition Metal Catalyzed Ullmann-type O-Arylation Reactions
Authors: Parvathi Santhoshkumar  , Rajalakshmi C. , Mathews Lydia Elizabeth , Sulay Rehin , Thomas Vibin Ipe
Published: April 2023

Transition metal-catalyzed reactions  have attracted much attention in synthetic organic chemistry due to their important role in the formation of C-heteroatom bonds. Ullmann coupling has risen in prominence in recent decades owing to its utilization in the synthesis of biaryl ethers found in a wide range of natural products together with biologically essential molecules, including antibiotics and major industrial polymers. In this article we provide the current understanding of the theoretical aspects of the underlying mechanism of the Ullmann-type O-arylation reaction.
Biological and technological indicators of the new silkworm hybrid “Istiklol”
Authors: Салимджанов С. , Умаров Ш.Р.
Published: April 2023

В этой статье наряду с перспективами развития отрасли шелководства в Республике Таджики­стан, рассмотрены результаты исследования, проведенного в Республиканском научно-исследовательском центре шелководства Республики Таджикистан, направленного на изучение влияния факторов внешних среды, в частности температуры и влажности на биологические, продуктивные и технологические показатели перспективного гибрида «Истиклол». Сравнительно проанализированы полученные в разные годы оживляемость грены, продолжительность гусеничного периода, жизнеспособность гусеницы, средняя масса живого кокона, выход шелка-сырца, разматываемость коконной оболочки, общая длина коконной нити, длина непрерывно разматываемой нити, метрический номер коконной нити вышеуказанного гибрида. Изучены устойчивость данного гибрида к неблагоприятным условиям внешней среды.

In this article, along with the prospects for the development of the sericulture industry in the Republic of Tajikistan, the results of a study conducted at the Republican Research Center for Sericulture of the Republic of Tajikistan, aimed at studying the influence of environmental factors, in particular temperature and humidity, on the biological, productive and technological indicators of a promising hybrid “Istiklol” are considered. The revival of egg, the duration of the caterpillar period, the viability of the caterpillar, the average weight of a living cocoon, the yield of raw silk, the unwinding of the cocoon shell, the total length of the cocoon thread, the length of the continuously unwound thread, the metric number of the cocoon thread of the above hybrid were analyzed comparatively. The resistance of this hybrid to adverse environmental conditions was studied.
utilisation de la méthode "ce que je sais, ce que je cherche" en classe de mathématiques : analyse de productions d'élèves
Authors: Goulet Marie-Pierre , Voyer Dominic
Published: April 2023

Nous avons étudié la façon dont l’activité de résolution de problèmes mathématiques est abordée en classe du primaire (école élémentaire), particulièrement lorsque celle-ci est abordée par l’entremise d’une méthode de type « ce que je cherche, ce que je sais ». Nous avons documenté la façon dont cette méthode est utilisée par des élèves québécois de quatrième année (9-10 ans) qui choisissent librement d’y avoir recours, c’est-à-dire sans que cette méthode leur soit imposée. Les productions de 45 élèves ont été analysées afin d’étudier la cohérence interne de la démarche mise en œuvre.
Low-temperature electrochemical ammonia synthesis: measurement reliability and comparison to Haber-Bosch in terms of energy efficiency
Authors: Rezai Fateme , Læsaa Søren , Ege Sahin Nihat , Catalano Jacopo , Dražević Emil
Published: April 2023

Recently several studies paved a way to nearly 100% selectivity of the electrochemical ammonia synthesis (EAS), which had been identified earlier as a main challenge. These results motivated us to benchmark the energy efficiency (EE) of EAS against the Haber-Bosch process. We present a method to calculate EE of EAS, which can be used by a broader audience. EAS studies historically suffered from reliability issues, and to avoid benchmarking of false-positive results, we established a method to calculate a reliability indicator to assess the measurement reliability of a published work. We used the indicator to evaluate the studies published in 2020, 2021 and 2022. We calculated the EE of EAS for works that were assessed as reliable with our indicator. We identified and discussed several promising systems and strategies enabling higher selectivity and EE. The EE of some aqueous EAS reports are up to 55%, and non-aqueous are below 15%.
MBX: A many-body energy and force calculator for data-driven many-body simulations
Authors: Riera Marc , Knight Christopher , Bull-Vulpe Ethan F. , Zhu Xuanyu , Smith Daniel G.A. , Simmonett Andrew C. , Paesani Francesco
Published: April 2023

MBX is a C++ library that implements many-body potential energy functions (PEFs) within the “many-body energy” (MB-nrg) formalism. MB-nrg PEFs integrate an underlying polarizable model with explicit machine-learned representations of many-body interactions to achieve chemical accuracy from the gas to the condensed phases. MBX can be employed either as a stand-alone package or as an energy/force engine that can be integrated with generic software for molecular dynamics and Monte Carlo simulations. MBX is parallelized internally using OpenMP, and can utilize MPI when available in interfaced molecular simulation software. MBX enables classical and quantum molecular simulations with MB-nrg PEFs, as well as hybrid simulations that combine conventional force fields and MB-nrg PEFs, for diverse systems ranging from small gas-phase clusters to aqueous solutions and molecular fluids to biomolecular systems and metal- organic frameworks.
Zero- to Low-field Relaxometry of Chemical and Biological Fluids
Authors: Alcicek Seyma , Put Piotr , Kubrak Adam , Alcicek Fatih Celal , Barskiy Danila , Gloeggler Stefan , Dybas Jakub , Pustelny Szymon
Published: April 2023

NMR relaxometry is an analytical method that provides information about the molecular environment, including even NMR “silent” molecules (spin-0), by analyzing the properties of NMR signals versus the magnitude of the longitudinal field. Conventionally, this technique has been performed at fields much higher than Earth’s magnetic field, but in this work, we present NMR relaxometry at zero and ultra-low magnetic fields (ZULFs). Operation under ZULFs allows us to investigate many slow (bio)chemical processes, whose timescale (milliseconds-seconds) coincides with a timescale of spin evolution. ZULFs regime also limits the detrimental role of T2 dephasing, which, in heterogeneous samples, is induced by magnetic susceptibility and often leads to line broadening, hence low-resolution spectra. Finally, in contrast to their high-field NMR, ZULF NMR measurements can be performed with inexpensive, portable/small-size sensors (atomic magnetometers). Here, we use ZULF NMR relaxometry in the analysis of (bio)chemical compounds containing 1H 13C, 1H-15N, and 1H-31P spin pairs. We also detected high-quality ULF NMR spectra of human whole blood at 0.8 μT, despite a shortening of spin relaxation by blood proteomes (e.g., hemoglobin). Information on relaxation times of blood, a potential early biomarker of inflammation, can be obtained in less than a minute and without the need for a sophisticated apparatus.
Metal-organic frameworks meet Uni-MOF: a revolutionary gas adsorption detector
Authors: Wang Jingqi , Liu Jiapeng , Wang Hongshuai , Ke Guolin , Zhang Linfeng , Wu Jianzhong , Gao Zhifeng , Lu Diannan
Published: April 2023

Gas separation is crucial for industrial production and environmental protection, with metal-organic frameworks(MOFs) offering a promising solution due to their tunable structural properties and chemical compositions. Traditional simulation approaches, such as molecular dynamics, are complex and computationally demanding. Although feature engineering-based machine learning methods perform better, they are susceptible to overfitting because of limited labeled data. Furthermore, these methods are typically designed for single tasks, such as predicting gas adsorption capacity under specific conditions, which restricts the utilization of comprehensive datasets including all adsorption capacities. To address these challenges, we propose Uni-MOF, an innovative framework for large-scale, three-dimensional MOF representation learning, designed for universal multi-gas prediction. Specifically, Uni-MOF serves as a versatile "gas adsorption detector" for MOF materials, employing pure three-dimensional representations learned from over 631,000 collected MOF and COF structures. Our experimental results show that Uni-MOF can automatically extract structural representations and predict adsorption capacities under various operating conditions using a single model. For simulated data, Uni-MOF exhibits remarkably high predictive accuracy across all datasets. Impressively, the values predicted by Uni-MOF correspond with the outcomes of adsorption experiments. Furthermore, Uni-MOF demonstrates considerable potential for broad applicability in predicting a wide array of other properties.