bluuebunny/crossref_metadata_2025 huggingface dataset:
The methylome of the model arbuscular mycorrhizal fungus, Rhizophagus irregularis, shares characteristics with early diverging fungi and Dikarya
Authors: Chaturvedi Anurag , Cruz Corella Joaquim , Robbins Chanz , Loha Anita , Menin Laure , Gasilova Natalia , Masclaux Frédéric G. , Lee Soon-Jae , Sanders Ian R.
Published: July 2021

Early-diverging fungi (EDF) are distinct from Dikarya and other eukaryotes, exhibiting high N6-methyldeoxyadenine (6mA) contents, rather than 5-methylcytosine (5mC). As plants transitioned to land the EDF sub-phylum, arbuscular mycorrhizal fungi (AMF; Glomeromycotina) evolved a symbiotic lifestyle with 80% of plant species worldwide. Here we show that these fungi exhibit 5mC and 6mA methylation characteristics that jointly set them apart from other fungi. The model AMF, R. irregularis, evolved very high levels of 5mC and greatly reduced levels of 6mA. However, unlike the Dikarya, 6mA in AMF occurs at symmetrical ApT motifs in genes and is associated with their transcription. 6mA is heterogeneously distributed among nuclei in these coenocytic fungi suggesting functional differences among nuclei. While far fewer genes are regulated by 6mA in the AMF genome than in EDF, most strikingly, 6mA methylation has been specifically retained in genes implicated in components of phosphate regulation; the quintessential hallmark defining this globally important symbiosis.
14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains
Authors: Pohl Pavel , Joshi Rohit , Petrvalska Olivia , Obsil Tomas , Obsilova Veronika
Published: July 2021

Neural precursor cell expressed developmentally down-regulated 4 ligase (Nedd4-2) is an E3 ubiquitin ligase that targets proteins for ubiquitination and endocytosis, thereby regulating numerous ion channels, membrane receptors and tumor suppressors. Nedd4-2 activity is regulated by autoinhibition, calcium binding, oxidative stress, substrate binding, phosphorylation and 14-3-3 protein binding. However, the structural basis of 14-3-3-mediated Nedd4-2 regulation remains poorly understood. Here, we combined several techniques of integrative structural biology to characterize Nedd4-2 and its complex with 14-3-3. We demonstrate that phosphorylated Ser342 and Ser448 are the key residues that facilitate 14-3-3 protein binding to Nedd4-2 and that 14-3-3 protein binding induces a structural rearrangement of Nedd4-2 by inhibiting interactions between its structured domains. Overall, our findings provide the structural glimpse into the 14-3-3-mediated Nedd4-2 regulation and highlight the potential of the Nedd4-2:14-3-3 complex as a pharmacological target for Nedd4-2-associated diseases such as hypertension, epilepsy, kidney disease and cancer.
Long-lived and multiplexed atom-photon entanglement interface with feed-forward-controlled readouts
Authors: Wang Sheng-zhi , Wang Min-jie , Wen Ya-fei , Xu Zhong-xiao , Ma Teng-fei , Li Shu-jing , Wang Hai
Published: July 2021

Quantum interfaces (QIs) that generate entanglement between photonic and spin-wave (atomic memory) qubits are basic building block for quantum repeaters. Realizing ensemble-based repeaters in practice requires quantum memory providing long lifetimes and multimode capacity. Significant progress has been achieved on these separate goals. The remaining challenge is to combine the two attributes into a single QI. Here, by establishing spatial multimode, magnetic-field-insensitive and long-wavelength spin-wave storage in laser-cooled atoms inside a phase-passively-stabilized polarization interferometer, we constructed a multiplexed QI that stores up to three long-lived spin-wave qubits. Using a feed-forward-controlled system, we demonstrated that a multiplexed QI gives rise to a 3-fold increase in the atom–photon (photon–photon) entanglement-generation probability compared with single-mode QIs. For our multiplexed QI, the measured Bell parameter is 2.51±0.01 combined with a memory lifetime of up to 1 ms. This work represents a key step forward in realizing fiber-based long-distance quantum communications.
Non-invasive analysis of pancreas organoids in synthetic hydrogels defines material-cell interactions and luminal composition
Authors: Jung Nathalie , Moreth Till , Stelzer Ernst H. K. , Pampaloni Francesco , Windbergs Maike
Published: July 2021

The study presents non-invasive imaging of pancreas organoids in synthetic hydrogels, highlighting the successful implementation of confocal Raman microscopy for the label-free analysis of material-cell interactions and luminal composition.
Correction: Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer
Authors: Achilli Silvia , Berthet Nathalie , Renaudet Olivier
Published: July 2021

Correction for ‘Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer’ by Silvia Achilli et al., RSC Chem. Biol., 2021, 2, 713–724. DOI: 10.1039/d1cb00007a.
Presenting porous–organic–polymers as next-generation invigorating materials for nanoreactors
Authors: Sarkar Chitra , Shit Subhash Chandra , Das Nitumani , Mondal John
Published: July 2021

This Feature Article represents the existing research activities about diverse synthetic approaches with possible modification of functionality of POPs (COFs, CTFs and some amorphous POPs) and their exciting applications (photocatalytic CO2 reduction, bio-mass upgradation & water splitting) as next generation nanoreactors.
Circularly permuted AsLOV2 as an optogenetic module for engineering photoswitchable peptides
Authors: Geng Lequn , Shen Jiaqi , Wang Wenjing
Published: July 2021

A circularly permuted AsLOV2 domain has been designed to photocontrol peptides by caging their C-terminus. This photoswitch provides a new module for engineering optogenetic tools and a general approach to lower the background of LOV-based tools.
Four component Passerini polymerization of bulky monomers under high shear flow
Authors: Tuten Bryan T. , Bui Aaron H. , Wiedbrauk Sandra , Truong Vinh X. , Raston Colin L. , Barner-Kowollik Christopher
Published: July 2021

We introduce a four component Passerini polymerization utilizing sterically bulky isocyanide monomers.
HFIP promoted thio(hetero)arylation of imidazoheterocycles under metal- and base-free conditions
Authors: Chaubey Narendra R. , Kapdi Anant R.
Published: July 2021

A new reaction methodology for thio(hetero)arylation of imidazoheterocycles under metal and base-free conditions. First report that describes linking of imidazoheterocycles with electron deficient heteroarenes through a sulphur atom.
Rhodium-catalysed direct formylmethylation using vinylene carbonate and sequential dehydrogenative esterification
Authors: Kato Moena , Ghosh Koushik , Nishii Yuji , Miura Masahiro
Published: July 2021

A rhodium-catalysed direct formylmethylation adopting vinylene carbonate as an ethynol equivalent is reported.
Long-lived emission beyond 1000 nm: control of excited-state dynamics in a dinuclear Tb(iii)–Nd(iii) complex
Authors: Kitagawa Yuichi , Matsuda Kenji , da Rosa Pedro Paulo Ferreira , Fushimi Koji , Hasegawa Yasuchika
Published: July 2021

This study reports the long-lived NIR emission of a Nd(iii) complex using a Tb(iii) donor at room temperature.
Multi-site Cr3+ occupation-related broadband NIR luminescence in Cr3+-doped Li3Mg2NbO6
Authors: Xiao Fen , Xie Chengning , Xie Shikun , Yi Rongxi , Yuan Huiling , Zhou Haolin
Published: July 2021

Broadband NIR luminescence from the Li3Mg2NbO6:Cr3+ phosphor is related to the multi-site occupation behavior of Cr3+.
Enhanced photocatalytic activity, transport properties and electronic structure of Mn doped GdFeO3 synthesized using the sol–gel process
Authors: Maity Ritwik , Dutta Alo , Halder Saswata , Shannigrahi Santiranjan , Mandal Kalyan , Sinha T. P.
Published: July 2021

Mn doping reduced the band gap to 1.72 eV from 2.18 eV which is confirmed from electronic structure calculations. GdFe0.7Mn0.3O3 exhibits 99% Rh-B degradation at 25 minutes. The multiple oxidation states of Fe and Mn enhances the conductivity and Mn doping reduces the barrier width which facilitates the charge transfer process.
Ultrafast Laplace NMR to study metal–ligand interactions in reversible polarisation transfer from parahydrogen
Authors: Tickner Ben. J. , Zhivonitko Vladimir V. , Telkki Ville-Veikko
Published: July 2021

Ultrafast Laplace NMR can monitor changes in ligand dynamics due to metal ligation and isotope exchange. A 300-fold sensitivity boost from SABRE hyperpolarisation can provide a 1440-fold time saving in determination of D and T2.