bluuebunny/crossref_metadata_2025 huggingface dataset:
Circular RNA circLMF1 regulates PDGF-BB-induced proliferation and migration of human aortic smooth muscle cells by regulating the miR-125a-3p/VEGFA or FGF1 axis
Authors: Yang Yanping , Mao Wenkai , Wang Liming , Lu Lin , Pang Yunfeng
Published: June 2021

Atherosclerosis is a major cause of cardiovascular disease, in which vascular smooth muscle cells (VSMCs) proliferation and migration play a vital role. Circular RNAs (circRNAs) have been reported to be correlated with the VSMCs function. Therefore, this study is designed to explore the role and mechanism of circRNA lipase maturation factor 1 (circLMF1) in Human aortic VSMCs (HASMCs). The microarray was used for detecting the expression of circLMF1 in proliferative and quiescent HASMCs. Levels of circLMF1, microRNA-125a-3p (miR-125a-3p), vascular endothelial growth factor A (VEGFA), and fibroblast growth factor 1 (FGF1) were determined by real-time quantitative polymerase chain reaction (RT-qPCR). Cell viability, cell cycle progression, and migration were assessed by Cell Counting Kit-8 (CCK-8), flow cytometry, wound healing, and transwell assays, respectively. Western blot assay determined proliferating cell nuclear antigen (PCNA), Cyclin D1, matrix metalloproteinase (MMP2), osteopontin (OPN), VEGFA, and FGF1 protein levels. The possible interactions between miR-125a-3p and circLMF1, and miR-125a-3p and VEGFA or FGF1 were predicted by circbank or targetscan, and then verified by a dual-luciferase reporter, RNA Immunoprecipitation (RIP), RNA pull-down assays. CircLMF1, VEGFA, and FGF1 were increased, and miR-125a-3p was decreased in platelet-derived growth factor-BB (PDGF-BB)-inducted HASMCs. Functionally, circLMF1 knockdown hindered cell viability, cell cycle progression, and migration in PDGF-BB-treated HASMCs. Mechanically, circLMF1 could regulate VEGFA or FGF1 expression through sponging miR-125a-3p. Our findings revealed that circLMF1 deficiency could inhibit cell viability, cell cycle progression, and migration of PDGF-BB stimulated atherosclerosis model partly through the miR-125a-3p/VEGFA or FGF1 axis, suggesting that targeting circLMF1 can be a feasible therapeutic strategy for atherosclerosis.
Acute Exercise and Cognitive Function in Alzheimer’s Disease
Authors: Ben Ayed Ines , Castor-Guyonvarch Naomie , Amimour Souad , Naija Salma , Aouichaoui Chirine , Ben Omor Sana , Tabka Zouhair , El Massioui Farid
Published: June 2021

Background: Many studies have shown the impact of acute aerobic exercises (AAE) on cognition in healthy adults or at a pre-dementia stage. Few studies, however, have explored the positive effects of AAE in moderate Alzheimer’s disease (ADM) patients. Objective: Evaluating the effect of AAE on cognitive functions in ADM patients. Methods: Overall, 79 (age: 69.62±0.99) ADM patients were recruited. Participants were divided into three groups according to the task: aerobic exercises done alone or combined with cognitive games presented on a screen, and a control group who performed a reading task. The aerobic exercise protocol consisted of a 20-min cycling exercise of moderate intensity, corresponding to 60%of the individual target maximal heart rate recorded in a 6-minute walking test. The participants’ cognition was monitored before and after the intervention using the Tower of Hanoi, Digit Span, and Stroop tasks. Results: After the exercise, the participants’ attention in both the physical and combined groups improved for the Stroop, the forward and backward Digit Span tasks, as well as the time taken to solve the Tower of Hanoi, although no significant differences were found in the number of moves taken in the latter. By contrast, the control group did not show any significant improvement for most of the cognitive tasks after the reading session. Conclusion: Current evidence suggests that AAE may help to improve cognitive functions in ADM patients. This improvement is enhanced when the exercise is combined with cognitive games. Safe and progressive types of exercises should be promoted among ADM patients.
Effects of Aerobic, Resistance, or Combined Exercise Training Among Older Adults with Subjective Memory Complaints: A Randomized Controlled Trial
Authors: Makino Taeko , Umegaki Hiroyuki , Ando Masahiko , Cheng Xian Wu , Ishida Koji , Akima Hiroshi , Oshida Yoshiharu , Yoshida Yasuko , Uemura Kazuki , Shimada Hiroyuki , Kuzuya Masafumi
Published: June 2021

Background: Physical exercise is suggested to be effective for preventing cognitive decline in older adults, but the relative efficacy of different types of exercise have yet to be clarified. Objective: This single-blinded randomized controlled trial was designed to investigate the differential effects of aerobic exercise training (AT), resistance exercise training (RT), and combined exercise training (CT) on cognition in older adults with subjective memory complaints (SMC). Methods: Community-dwelling older adults with SMC (n = 415; mean age = 72.3 years old) were randomly assigned to one of the four groups: AT, RT, CT, or control group. The study consisted of two phases: a 26-week intervention and a 26-week follow-up. The participants were evaluated at baseline, 26 weeks (postintervention), and 52 weeks (follow-up). The primary outcome of this study was memory function, which was assessed using the Logical Memory II subtest of the Wechsler Memory Scale-Revised (WMS-R) score. The secondary outcomes included global cognitive function, verbal fluency, working memory, processing speed, and executive functions. Results: Intention-to-treat analysis by a mixed-effect model repeated measure showed that the AT group had significantly improved performance on the WMS-R Logical Memory II test (2.74 [1.82–3.66] points) than the control group (1.36 [0.44–2.28] points) at the postintervention assessment (p = 0.037). The effect was more pronounced in those without amnesia than those with amnesia. No significant improvement was observed in the RT and CT groups. Conclusion: This study suggests that AT intervention can improve delayed memory in community-dwelling older adults, particularly in individuals without objective memory decline.
Recommendations for Preclinical Testing of Treatments Against Alzheimer’s Disease-Related Epileptiform Spikes in Transgenic Rodent Models
Authors: Jin Nanxiang , Babiloni Claudio , Drinkenburg Wilhelmus H. , Hajós Mihály , Nygaard Haakon B. , Tanila Heikki
Published: June 2021

Recent evidence suggests that about 30%of patients with mild to moderate Alzheimer’s disease (AD) without a known diagnosis of epilepsy may display epileptiform spikes during electroencephalographic (EEG) recordings. These abnormal discharges occur predominantly during sleep and may be associated with accelerated disease progression. Subclinical spikes may represent a relevant target for clinical drug interventions, and there is a clear unmet need for preclinical testing of novel disease modifying agents in suitable animal models. Transgenic rodent models of AD pathology exhibit various forms of epileptiform EEG activity related to the abnormal levels of amyloid species in the brain. Among them, large-amplitude cortical and hippocampal EEG spikes in mouse and rat AD models may be reminiscent of the subclinical epileptiform EEG spikes recorded in some AD patients. This article reports the recommendations of a multidisciplinary panel of experts on optimal EEG markers and experimental designs to measure and report epileptiform activities and their response to symptomatic and disease-modifying drugs in transgenic AD model rodents. These recommendations may harmonize future preclinical EEG studies in the drug discovery research and may increase the comparability of experimental outcomes and their translational clinical value.
Dementia and COVID-19, a Bidirectional Liaison: Risk Factors, Biomarkers, and Optimal Health Care
Authors: Toniolo Sofia ,   the Management Group of the EAN Dementia and Cognitive Disorders Scientific Panel, Scarioni Marta , Di Lorenzo Francesco , Hort Jakub , Georges Jean , Tomic Svetlana , Nobili Flavio , Frederiksen Kristian Steen
Published: June 2021

Cognitive impairment following SARS-CoV-2 infection is being increasingly recognized as an acute and possibly also long-term sequela of the disease. Direct viral entry as well as systemic mechanisms such as cytokine storm are thought to contribute to neuroinflammation in these patients. Biomarkers of COVID-19-induced cognitive impairment are currently lacking, but there is some limited evidence that SARS-CoV-2 could preferentially target the frontal lobes, as suggested by behavioral and dysexecutive symptoms, fronto-temporal hypoperfusion on MRI, EEG slowing in frontal regions, and frontal hypometabolism on 18F-FDG-PET. Possible confounders include cognitive impairment due to hypoxia and mechanical ventilation and post-traumatic stress disorder. Conversely, patients already suffering from dementia, as well as their caregivers, have been greatly impacted by the disruption of their care caused by COVID-19. Patients with dementia have experienced worsening of cognitive, behavioral, and psychological symptoms, and the rate of COVID-19-related deaths is disproportionately high among cognitively impaired people. Multiple factors, such as difficulties in remembering and executing safeguarding procedures, age, comorbidities, residing in care homes, and poorer access to hospital standard of care play a role in the increased morbidity and mortality. Non-pharmacological interventions and new technologies have shown a potential for the management of patients with dementia, and for the support of their caregivers.
Pairwise deep learning to rank for top-N recommendation
Authors: Zhou Wang , Yang Yujun , Du Yajun , Haq Amin Ul
Published: June 2021

Recent researches indicate that pairwise learning to rank methods could achieve high performance in dealing with data sparsity and long tail distribution in item recommendation, although suffering from problems such as high computational complexity and insufficient samples, which may cause low convergence and inaccuracy. To further improve the performance in computational capability and recommendation accuracy, in this article, a novel deep neural network based recommender architecture referred to as PDLR is proposed, in which the item corpus will be partitioned into two collections of positive instances and negative items respectively, and pairwise comparison will be performed between the positive instances and negative samples to learn the preference degree for each user. With the powerful capability of neural network, PDLR could capture rich interactions between each user and items as well as the intricate relations between items. As a result, PDLR could minimize the ranking loss, and achieve significant improvement in ranking accuracy. In practice, experimental results over four real world datasets also demonstrate the superiority of PDLR in contrast to state-of-the-art recommender approaches, in terms of Rec@N, Prec@N, AUC and NDCG@N.
Towards corpus and model: Hierarchical structured-attention-based features for Indonesian named entity recognition
Authors: Fu Yingwen , Lin Nankai , Lin Xiaotian , Jiang Shengyi
Published: June 2021

Named entity recognition (NER) is fundamental to natural language processing (NLP). Most state-of-the-art researches on NER are based on pre-trained language models (PLMs) or classic neural models. However, these researches are mainly oriented to high-resource languages such as English. While for Indonesian, related resources (both in dataset and technology) are not yet well-developed. Besides, affix is an important word composition for Indonesian language, indicating the essentiality of character and token features for token-wise Indonesian NLP tasks. However, features extracted by currently top-performance models are insufficient. Aiming at Indonesian NER task, in this paper, we build an Indonesian NER dataset (IDNER) comprising over 50 thousand sentences (over 670 thousand tokens) to alleviate the shortage of labeled resources in Indonesian. Furthermore, we construct a hierarchical structured-attention-based model (HSA) for Indonesian NER to extract sequence features from different perspectives. Specifically, we use an enhanced convolutional structure as well as an enhanced attention structure to extract deeper features from characters and tokens. Experimental results show that HSA establishes competitive performance on IDNER and three benchmark datasets.
An automatic assessment of road condition from aerial imagery using modified VGG architecture in faster-RCNN framework
Authors: Malini A. , Priyadharshini P. , Sabeena S.
Published: June 2021

To develop a surveillance and detection system for automating the process of road maintenance work which is being carried out by surveying and inspection of roads manually in the current situation. The need of the system lies in the fact that traditional methods are time-consuming, tiresome and require huge workforce. This paper proposes an automation system using Unmanned Aerial Vehicle which monitors and detects the pavement defects like cracks and potholes by processing real-time video footage of Indian highways. The collected data is processed and stored as images in a road defects database which serves as input for the system. The behavior of Region Proposal Network (RPN) is made smooth by varying the number of region proposals utilized in the model. A regularization technique called dropout is used to achieve higher performance in the proposed Faster Region based Convolutional Neural Networks object detection model. The detections are made with 62.3% mean Average Precision @ Intersection over Union (IoU)> = 0.5 for the generation of 300 region proposals which is a good score for object detections. The comparisons between proposed and existing systems shows that the proposed Faster RCNN with modified VGG-16 performs well than the existing variants.
Research on the evolution of movement difficulty of competitive aerobics based on digital image processing
Authors: Bai Suping , Chen Lixin , Zhao Ligong
Published: June 2021

Competitive aerobics is a sports project which combines music, aerobics, difficulty and performance as the whole, and takes health, strength and beauty as its movement characteristics. Competitive aerobics is one of the sports that is dominated by skills, and the technical requirements are higher. Through the analysis of the existing literature, the current research on the difficulty of aerobics is only in the general qualitative description and experience summary. So far, there is no comprehensive analysis of the evolution of the competitive gymnastics articles, in the theoretical aspects of the study which is more general, limited. In this work, the method of digital image processing is used to focus on the evolution of the difficulty of aerobics. Combining the rules of the international competitive aerobics competition in each cycle, this work analyzes the statistical data of the movement difficulty of the aerobics championships, discusses the difficulty of aerobics development and evolution process, from summing up the characteristics of the development of difficult movements,the development trend of difficult movements of competitive aerobics is scientifically predicted.
Data Protection Using Polymorphic Pseudonymisation in a Large-Scale Parkinson’s Disease Study
Authors: van Gastel Bernard E. , Jacobs Bart , Popma Jean
Published: June 2021

This paper describes an advanced form of pseudonymisation in a large cohort study on Parkinson’s disease, called Personalized Parkinson Project (PPP). The study collects various forms of biomedical data of study participants, including data from wearable devices with multiple sensors. The participants are all from the Netherlands, but the data will be usable by research groups worldwide on the basis of a suitable data use agreement. The data are pseudonymised, as required by Europe’s General Data Protection Regulation (GDPR). The form of pseudonymisation that is used in this Parkinson project is based on cryptographic techniques and is ‘polymorphic’: it gives each participating research group its own ‘local’ pseudonyms. Still, the system is globally consistent, in the sense that if one research group adds data to PPP under its own local pseudonyms, the data become available for other groups under their pseudonyms. The paper gives an overview how this works, without going into the cryptographic details.
¿Pueden los adolescentes tomar mejores decisiones? La respuesta de la Física
Authors: Reyes Martín Héctor , García González Juan Manuel , José Antonio Mirón Canelo José Antonio
Published: June 2021

Tradicionalmente, aprender Física es una tarea complicada. En el presente estudio queremos conocer si hay relación entre el aprendizaje de la Física de modo mayéutico o socrático y las funciones ejecutivas del cerebro. 69 estudiantes preuniversitarios que aprendieron Física empleando un método fundamentado en el funcionamiento del cerebro fueron comparados con un grupo que aprendió Física empleando la clase magistral, exactamente con el mismo N. Ambos grupos fueron analizados con el test de Stroop para buscar diferencias en las funciones ejecutivas, más concretamente en la inhibición de las respuestas inmediatas e intuitivas. El test-T determina que existe una diferencia significativa entre ambos grupos (p<0.036) en el control de la interferencia o inhibición. Estos resultados podrían indicar que esta metodología fundamentada en el funcionamiento del cerebro mejora el proceso de razonamiento de los estudiantes, puesto que sabemos que la cingulada anterior y el lóbulo frontal funcionan como un tándem en ese proceso. Los resultados del presente estudio sugieren que hay una mejora en la inhibición que está relacionada con la forma de aprender. El método propuesto parece que refuerza las funciones ejecutivas del cerebro y tal vez sería posible emplear dicho método en otras asignaturas.
Skansen tourist activity in the system of updating the resources of cultural intangible heritage
Authors: Dychkovskyy Stepan
Published: June 2021

The purpose of the article consists of the study of the activity of skansen in the intangible cultural heritage system. The methodology is the application of historical, bibliographic, and analytical methods. The scientific novelty of the work is to justify the appropriateness and application of the new concept of tourism activity of scans in the system of intangible cultural heritage. Conclusions. Features of the development of tourism in a post-industrial society influenced the conceptual approaches to the museum topes, which first broadcast chronological meaning, but with the proliferation of skansen museums was beyond the phenomenological limits of time and space. The proliferation of scansions as interactive open-air exhibits became a reflection of changes in the cultural and socio-economic life of modern society. The trends in the development of active consumerism in the social and economic spheres, globalization processes, the growth of cultural and creative industries have identified new areas of activity for museums - skansens, which transformed from museums that showed ethnographic collections in the space of the formation of a new cultural being.
Cultural-anthropological origins of the mask of initiation physicality
Authors: Olha Kostiuk
Published: June 2021

The purpose of the article is to study the cultural-anthropological origins of the mask, which make it possible to interpret the initiation of physicality, which in the process of initiation acquired the signs of psychosomatic modification. The research methodology is based on the use of psychoanalytic, structural-functional, semiotic, and cultural-anthropological methods. Scientific novelty. In the study of cultural-anthropological origins of the mask of initiation physicality, used ideas of the «collective unconscious» of K. Jung, the theory of social character by E. Fromm, the methods of structural anthropology by K. Levi-Strauss, and analysis of ritual functions by K. Lorenz were used. The given examples of initiation in youth associations, male unions, subcultures, countercultures allow us to determine the cultural-anthropological origins of the mask in rituals and initiation rituals as an appeal to a perfect image, which symbolically possessed an advantage in natural-biological and psychological aspects. Conclusions. In the interpretation of the initiation physicality, which in the process of initiation acquired signs of psychosomatic modification, the cultural-anthropological origins of the mask are considered, represented by the ideas of the «collective unconscious» of K. Jung (Persona – Anima), the theory of social character by E. Fromm («to have» – «to be»). The study of experience, the relationship between biological and social in human behavior is represented by the methods of structural anthropology by K. Levi-Strauss, by the analysis of ritual functions from the standpoint of natural-biological existence – according to K. Lorentz. The given examples of initiation in youth associations, male unions, subcultures, countercultures allow us to determine that most often in rituals and initiation rituals, a perfect image was chosen, which symbolically possessed an advantage in natural-biological and psychological aspects.
Signs of desacralization of eastern slavic food in modern conditions: culturological analysis
Authors: Kobzar Maryna
Published: June 2021

The purpose of this article is to highlight the ways in which some foods in the modern East Slavic diet lose their sacred significance and acquire the status of everyday food, and to highlight the consequences of these processes as well. Methodology. In the work the complex of the following methods was applied: comparative, logical-analytical, semiotic, synchronic, diachronic. The scientific novelty is to implement a culturological analysis of the food products’ image the main desacralization signs in the East Slavic culinary traditions, which have been transformed at the present stage due to the development of globalization and integration processes in the world cultural space. Conclusions. It was the study found that the format of food consumption "fast food" with its principles of universality and speed, sustainable development of new food technologies, the availability of variety in food, numerous promotional products on the gastronomic theme, the emergence of catering establishments in East Slavic cities with elements of other gastronomic traditions have led to a certain situation: 1) leveling of national traditions in food culture; 2) devaluation of the sacred status of certain types of food, which were sacred among the Eastern Slavs a century ago; 3) resacralization in gastronomic culture. Traditional edible products have been replaced by other products from different cultures, that is, some sacred objects have been replaced by others depending on social, historical, political conditions. This occurs against the background of cultural expansion (Americanization, Easternization, and other processes in the culture of cooking and eating); 4) remythologization of modern culture, when the process of myth-making is revived. It was revealed, that new myths are being created in society, which is often illusory.
Formation of socio-cultural traditions in Uzhansk National Nature Park
Authors: Palamarchuk Svitlana , Byrkovych Viktor , Shvets Iryna
Published: June 2021

The purpose of the article is to study the formation of socio-cultural traditions as an effective mechanism through which to preserve the cultural, spiritual, and material experience of previous generations, as well as the reproduction of ethnocultural values ​​in the cultural heritage of society. The methodology consists of the application of general scientific and special research methods. The scientific novelty of the obtained results lies in the study of the formation of socio-cultural traditions on the basis of Uzhansky National Nature Park for the preservation of socio-cultural experience as one of the ways of development of modern society. Conclusions. Given the above, it should be noted that the formation of socio-cultural traditions in the population on the example of Uzhansky National Nature Park, is one of the components of modern cultural development, which plays an important role in preserving the spiritual and material experience of previous generations. Tourist cultural and educational activities are aimed at creating comprehensive conditions for the formation of personality, self-realization of the spiritual potential of man. Socio-cultural traditions are formed not only by the acquisition of historical-cultural experience, but also by modern socio-cultural practices used by people, and the formation of a harmonious society will depend on this.
Courtly Motives In The Art Of The High Middle Ages
Authors: Slivinska Alina , Tzvetkova Larysa
Published: June 2021

Purpose of the article. The article presents a study of courtly motives in the art of the high Middle Ages and the foundations of the ideological and figurative-symbolic representation of courtly images in various artistic forms of this era. Methodology. The study of the content of courtly motives and images, the definition of the ideological foundations of their figurative and symbolic representation was carried out through the use of historical, analytical, symbolic, and allegorical methods. Scientific novelty. The article examines courtly motives and courtly images presented in the art of the High Middle Ages, identifies the ideological foundations of their figurative and symbolic representation in various artistic forms of this era. Conclusions.  The visual images of medieval masters create the world of courtly, filling the courtly universe with numerous subjects that reflect the image and lifestyle of both knights and their Beautiful ladies. And thus they help to understand the norms and prescriptions of courtesy, the models of the participants' behavior in the courteous action, the corresponding rituals and etiquette norms of courteous relations, their attributes, and stylistics. In order to do this, the artists used various techniques - bright colors, saturation with symbols, heraldry, outfits, etc. Especially popular was the use of the rose image, which became the quintessence of Gothic art, its courtly and religious symbol, the embodiment of the ideal of chivalry to the Beautiful Lady, and a kind of reflection of the Christian image of the Virgin Mary.
Book publishing in Ukraine in the second half of the 20th century and artistic illustration in the works of V. Poltavets
Authors: Poltavets-Guida Oksana
Published: June 2021

The purpose of the article is to consider the graphic works of V. Poltavets-illustrator in the context of the development of book printing in Ukraine in the second half of the twentieth century, conduct a comparative analysis of the development of this industry in different eras, and identify their relationship. The methodology of the article is based on the chronological method of historical research, the biographical method, the method of observing the artist’s practical activities in different time periods, the method of analyzing works of art. The scientific novelty consists in the chronological systematization and comparative analysis of typography and graphic art in different historical periods, the study of the continuity of traditions and innovation in art, their interrelation, and a sequential examination of the creative heritage of the famous artist. Conclusion. The analysis shows a high level of development of publishing in Ukraine, the presence of art school and talented illustrators, indicates insufficient scientific coverage of this topic.
DIGITAL SOCIETY LIBRARY IN PROVIDING SYSTEM SUPPORT TO SCIENCE RESEARCH
Authors: Lobuzina Kateryna , Harahulia Serhii , Lobuzin Ivan
Published: June 2021

The purpose of the article is to review and analyze the participation of libraries in the maintenance of modern research information management systems that provide scientists with the necessary digital services and effectively support digital scientific communication. The methodology of the study is a set of system analysis of changes in the providing of libraries to support research in the digital environment. The scientific novelty of the article is the generalization of key trends in the development of integrated library systems for supporting scientific activities and the development of the concept of the library portal of the National Academy of Sciences of Ukraine. Conclusions. Modern research information systems are an effective tool for managing research data. A critical aspect of supporting such systems is the quality of the data that librarians can provide at the appropriate level. The library portal of the National Academy of Sciences of Ukraine, created and maintained by the Vernadsky National Library of Ukraine, built on the principles of integrated scientific information systems, will preserve and provide access to documentary heritage sources and modern sources of scientific information, provide a single access point to consolidated achievements academic science, will ensure the integration of portal metadata into international scientific information systems.
Key words: research information systems, research support systems, research libraries, academic science, research information management, research metadata, library knowledge portals.
DOCUMENTARY FUND AS A REFLECTION LEVEL OF INFORMATION CULTURE OF THE LIBRARY
Authors: Paleкha Yuriy , Kobyzhcha Natalya
Published: June 2021

The purpose of the article is to define the essence of the informational culture of the library, that represents the created documentary fund as an information product that is the result of the joint efforts of the staff, including its modeling, composition, and organization; to identify key elements and analyze components; outline directions for further research in terms of meeting the needs of the information society in the digital age. The methodology is to apply a culturological and systematic approach, general scientific methods of cognition, and the method of moving from the abstract to specific aspects. The scientific novelty of the work is to study the informational culture of the library and its documentary fund as a consolidated information product of joint efforts of its staff, which serves as an indicator of the level of the corporate culture of the library on the one hand and the informational culture of society on the other. The factors due to which the modern head of the library should take care of the informational culture of his institution, the main features and levels of the informational culture of the modern library are elaborated. Conclusions. The documentary fund as a product of joint activity and the main object of cultural creativity of the library staff can be presented as a complex, multidimensional structure, including the ability to collect and analyze source information, the ability to create electronic databases, knowledge of information retrieval systems and information retrieval techniques, ability to process information, skills of structuring documented information, knowledge of methods of preparation of different information documents, ability to provide information services. The combination of the main elements of the informational culture of the library is based on the principles of complexity, differential approach, and continuity and gives a new vision and understanding of the need for joint work on the formation of its documentary fund. The information culture of the library requires further research and detailed analysis of its components.
Key words: informational culture; documentary fund; joint information product; information technologies; digital age.
Third Party-Certifications in Aquaculture
Authors: Roan Emily H. , Patterson Joshua , DiMaggio Matthew , Yanong Roy
Published: June 2021

This publication provides information on common third-party certification programs for aquaculture products, mostly those intended for human consumption. The goal of this document is to increase consumer awareness and understanding of what commonly observed third-party certification labels signify. Includes some discussion of certification programs for ornamentals and baitfish.
Cuban Laurel Thrips, Gynaikothrips ficorum (Marchal) (Insecta: Thysanoptera: Phlaeothripidae)
Authors: Denmark Harold A. , Fasulo Thomas R. , Funderburk Joseph E.
Published: June 2021

Watson (1923) recorded the Cuban laurel thrips in Florida as Gynaikothrips uzeli (Zimmerman 1900). Since Priesner (1939) found that G. uzeli and G. ficorum (Marchal 1908) are distinct species, most specialists accept ficorum as the name of the Cuban laurel thrips. Specimens supposedly collected in Florida in 1887 are in the U.S. National Museum. G. ficorum appears in the Entomological Society of America's common name list as the Cuban laurel thrips, and is the name used here. This document is EENY-324 (IN599) (originally published as DPI Entomology Circular 59), one of a series of Featured Creatures from the Entomology and Nematology Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Published: August 2004. Revised: December 2005. 

EENY324/IN599: Leaf-Gall Thrips of Ficus Gynaikothrips ficorum (Marchal) and Gynaikothrips uzeli (Zimmerman) (Insecta: Thysanoptera: Phlaeothripidae) (ufl.edu)
Naturally Occurring Radionuclides in Agricultural Products
Authors: Hanlon Edward A.
Published: June 2021

This document is a summary of research with the naturally occurring radionuclides in agricultural products associated with phosphatic clays in Florida. This document is SL221, a fact sheet of the Soil and Water Science Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Originally published as SS-MLR-5, June 1993. Revised as SL221, December 2004.
GAMBARAN TINGKAT DEPRESI PADA LANSIA DI MASA PANDEMIC COVID-19
Authors: Hartutik Sri , Nurrohmah Anjar
Published: June 2021

Pandemi Covid -19 merupakan bentuk kasus baru di dunia kesehatan yang mempunyai beragam dampak, baik biologis, psikologis, sosial dan spiritual. Kondisi seperti ini harus benar-benar diwaspadai terutama pada usia rentan dan resiko yaitu salah satunya usia lansia. Depresi pada lansia merupakan gangguan psikiatri dan merupakan masalah kesehatan mental yang sering terjadi dikalangan lanjut usia. Prevalensi depresi didunia sekitar 8-15%. Hasil survey dari berbagai negara di dunia diperoleh prevalensi rata- rata depresi pada lansia adalah 13,5 % dengan perbandingan wanita:pria 14,1: 8,6 dimana wanita dua kali lebih banyak daripada pria. Penelitian ini bertujuan untuk Mengetahui gambaran tingkat depresi pada lansia di Masa Pandemic Covid-19. Jenis penelitian ini adalah penelitian desain deskriptif cross sectional dengan teknik consecutive sampling yang bertujuan untuk melihat gambaran tingkat depresi lansia menggunakan instrument penelitian berupa kuesioner Geriatric Depression Scale Short Form (GDS-S). Berdasarkan penelitian didapatkan hasil Umur lansia yang mengalami depresi pada masa Pandemic Covid-19 sebagian besar adalah Usia lanjut (60–74 tahun), jenis kelamin perempuan, status perkawinan lansia sebagian besar  janda, riwayat penyakit lansia sebagian besar  hipertensi, tingkat pendidikan lansia sebagian besar SD. Kesimpulan penelitian gambaran tingkat depresi pada lansia pada masa pandemic covid-19 sebagian besar mengalami depresi ringan.
Depression in the elderly is a psychiatric disorder and is a mental health problem that often occurs among the elderly. The prevalence of depression in the world is around 8-15% and survey results from various countries in the world show that the average prevalence of depression in the elderly is 13.5% with the ratio of women: men is 14.1: 8.6 where women are twice as many as men. . This research aimed to determine the level of depression in the elderly during the Covid-19 Pandemic. This type of research used a cross sectional descriptive design with consecutive sampling technique which aims to describe the level of depression in the elderly using a research instrument in the form of a Geriatric Depression Scale Short Form (GDS-S) questionnaire. The result showed Depression during the Covid-19 Pandemic was mostly elderly (60 - 74 years), female sex, most of the elderly marital status was widowed, history of elderly disease was mostly hypertension, education level of the elderly was mostly elementary school. The description of the level of depression in the elderly during the Covid-19 pandemic mostly experienced mild depression.
Controle social: uma análise entre percepção e prática
Authors: Carvalho de Santana Pinho Ruth , Lima do Vale Taianny Sterphanny
Published: June 2021

O Controle Social é essencial para legitimar a gestão pública, uma vez que o cidadão acompanha e fiscaliza as ações do governo, no entanto, o indivíduo esbarra em questões que impedem o pleno exercício da participação social. Nesse contexto, constitui objetivo principal deste estudo avaliar a relação entre a percepção e a prática do Controle Social. Para tanto, foi feita uma pesquisa quantitativa envolvendo 307 alunos do curso de Ciências Contábeis da Universidade Federal do Ceará. O instrumento de coleta utilizado foi o questionário. Adicionalmente, utilizou-se o teste de Correlação de Spearman para encontrar a relação entre as variáveis. Os resultados obtidos possibilitaram constatar a correlação positiva entre percepção e prática; o semestre e o lugar que trabalha são fatores relacionados com a prática do Controle Social, e a falta de ações promovedoras do Controle Social foi apontada como a principal barreira ao exercício da participação cidadã. Concluiu-se que a prática do Controle Social está associada à importância atribuída ao direito, porém o nível de engajamento do cidadão ainda é muito baixo, já que o indivíduo esbarra em questões culturais, sociais e políticas.
Portal da Transparência: do que se diz e o que se faz com o cartão de pagamento do governo federal
Authors: Fernandes Rafael Pereira de Fontes Ewerton , Souza Eliabe Roberto de , Carla Ceolin Alessandra , Aparecida da Silva Santos Liliane
Published: June 2021

Com a criação do Portal da Transparência do Governo Federal, a sociedade brasileira passou a dispor de uma nova ferramenta para suprir a demanda sobre o controle social. O objetivo geral desta pesquisa foi analisar como o Portal da Transparência do Governo Federal proporciona a transparência dos dados sobre a utilização dos recursos públicos com o uso de Cartão de Pagamento do Governo Federal no ano de 2019. Esta pesquisa teve caráter exploratório, os dados foram obtidos por meio do Painel “Cartões de Pagamentos” do Portal da Transparência e foram analisados em categorias temáticas ou unidades de análise. Os resultados revelam que o Portal da Transparência do Governo Federal disponibiliza dados sobre a utilização do Cartão de Pagamento do Governo Federal, porém existe um descompasso quanto à finalidade do uso do cartão de pagamento, que é o suprimento de fundos e o atendimento a eventuais despesas. Conclui-se, com esta pesquisa, que o Portal da Transparência permite a divulgação dos gastos públicos federais e com tal prática é possível verificar a falta de publicidade de determinados órgãos que usam o Cartão de Pagamento do Governo Federal, o descumprimento no atendimento a eventuais despesas e a ausência de planejamento no uso dos recursos públicos.
Teachers' Implementation of and Stages of Concern Regarding English Language Arts (ELA) Common Core State Standards (CCSS) in New York State
Authors:   , Ogbonna Aloze
Published: June 2021

Problem In the State of New York, the adoption and implementation of the Common Core State Standards (CCSS) and associated high-stakes assessments have sparked debates among educators, parents, students and politicians. Educators are concerned about its impact on students' test scores, graduation rates and school funding. With mounting accountability threats, teachers are forced to teach to the test in order to produce desirable test scores (Zimmerman, 2010, as cited in Pinar, 2012, p.17). Unfortunately, there were no studies that promoted understanding of teachers' concerns and the extent to which they were implementing the CCSS. The purpose of this study was to investigate teachers' concerns and the extent to which they were implementing the CCSS in language arts in the state of New York. Method The design of this study is a non-experimental quantitative design using survey research methodology. A survey using a modified Stages of Concern Questionnaire (SoCQ) and a researcher-developed implementation of language arts core standards questionnaire were given to Grades 6-12 ELA teachers from 75 selected schools in New York state. Seventy-five teachers responded to the questionnaire with 53 useable responses. The data was analyzed using descriptive statistics and bivariate correlation. Results Respondents were mostly from urban/suburban schools (90.4%). Teachers implement 13 of the 15 common core standards in language arts at least once a week (M=4.02 to M=6.15). Levels of implementation were similar in both middle and high schools (p>.05) and appear to be unrelated to number of years implementing the CCSS. Approximately half (52.8%) were at concern stages 4 to 6. And overall, there is no relationship between stage of concern and levels of implementation of the common core standards. Conclusions Teachers are adequately implementing language arts common core standards in New York. Half of the teachers' concerns are generally about how implementation of the standards affect their students and their colleagues. The other half are concerned about how implementation affects them personally. To achieve the objective of the curriculum and the Every Student Succeeds Act (ESSA), teachers must continue to receive targeted professional development in their identified areas of needs.
Management of 2, 4- Dichlorophenoxyacetic Acid Intoxication by Hemodialysis: A Case Report
Authors:   Department of Pharmacodynamic and Toxicology, Mashhad University of Medical Sciences, Mashhad, Iran., Moshiri Mohammad , Mousavi Seyed Reza ,   Department of Clinical Toxicology and Medical Toxicology, Mashhad University of Medical Sciences, Mashhad, Iran., Etemad Leila ,   PhD.of Toxicology, Pharmaceutical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Published: June 2021

Background: The herbicide 2, 4-dichlorophenoxyacetic acid (2, 4-D) can cause moderate to lethal poisoning. Although urine alkalization has been recommended as the main treatment, hemodialysis (HD) may be more effective in severe cases. Case: On 24th June 2014, a 53- year-old man ingested a high amount of 40% 2, 4-D. He suffered from mouth and epigastric burning sensation, vomiting and nausea. He was treated, in Emam Reza’s Hospital of Mashhad University Of Medical Sciences, Mashhad , Iran, with maintenance daily fluid infusion plus 10 meq/L NaHCO3. Up to 9 hours after exposure, he became progressively stuporous. He developed diarrhea and hypotension, BP=100/60, unresponsive to volume replacement therapy. He received regular hemodialysis (HD) with bicarbonate for three hours. At the end of HD, his blood pressure rose to 110/70 and the level of consciousness began to improve. Four hours later, he was fully conscious with stable blood pressure (130/80 mmHg). Conclusion: HD may be an effective, safe and fast method for 2, 4-D high dose intoxication induced coma.
Comparison of Effects and Side Effects of Two Naloxone-Based Regimens in Treatment of Methadone Overdose
Authors:   Department of Emergency Medicine, Arak University of Medical Science, Arak, Iran., Yazdanbakhsh Arash , Kazemifar Amir Mohammad ,   Department of Toxicology, Qazvin University of Medical Science, Qazvin, Iran., Nazari Kamyar ,   MD, Arak University of Medical Science, Arak, Iran., Sadeghi Sedeh Bahman ,   Department of Social Medicine, Arak University of Medical Science, Arak, Iran., Solhi Hassan ,   Department of Toxicology, Arak University of Medical Science, Arak, Iran.
Published: June 2021

Background: Acute opioid overdose is a common cause of admission in emergency department. In spite of the fact that naloxone is the main therapy for decades, there are controversies about the proper way of its use. This study aimed to compare two most recommended administration modes for naloxone. Methods: In this single-blind clinical trial, 80 patients with methadone overdose syndrome were randomly divided into two equal groups. The patients in infusion group received a constant infusion of naloxone preparation while in the patients in PRN group, naloxone was administered only if needed clinically. Severity of withdrawal syndrome was evaluated after 30 min, 3 h, and 12 h of the treatments in both groups. Results: Eighty patients completed the study (10 women and 70 men). Both groups were similar in terms of mean age, sex ratio, and the severity of intoxication. The severity of withdrawal symptom was significantly lower in the PRN group (P<0.001). Conclusion: Naloxone administration as PRN mode lowers the rate and severity of withdrawal syndrome. It is recommended as the preferred mode of naloxone administration.
Effect of Sodium Metabisulfite on Rat Ovary and Lipid Peroxidation
Authors:   Department of Physiology, Arsanjan Branch, Islamic Azad University, Arsanjan, Iran., Rezaee Nahid , Nematollahi Zahra ,   Department of Physiology, Arsanjan Branch, Islamic Azad University, Arsanjan, Iran., Shekarforous Shahnaz ,   Department of Physiology, Arsanjan Branch, Islamic Azad University, Arsanjan, Iran., Hoseini Ebrahim ,   Department of Biology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran.
Published: June 2021

Background: Many health problems are related to lifestyle and dietary factors. Since ancient times, food additives such as sulfites have been used to preserve foods. Diverse effects of sulfites on multiple organs have been reported but its effect on female reproductive organ has not been fully elucidated. The aim of this study was to investigate the effects of sodium metabisulfite (SMB) on ovarian tissue in adult rats. Methods: Four groups of female rats (n=32) were used. The experimental rats received 10, 100 and 260 mg/kg SMB for 28 days (S10, S100 and S260 groups, respectively). The control rats received distilled water for the same period. The ovarian volume, weight and the number of different types of follicles were estimated by stereological methods. Lipid peroxidation is assessed indirectly by the measurement of malondialdehyde (MDA), using the thiobarbituric acid (TBA) method. Results: The results showed a significant decrease in the ovarian volume, the number of primordial, primary, secondary, grafian follicles and corpus luteum in the SMB-treated animals compared with the control group (P < 0.05). In comparison to the control group, the number of atretic follicles increased in the SMB-treated rats. MDA was significantly increased in S260 group compared to the control group. Conclusion: The present data confirm sulfite-induced structural changes in the ovary. Increased level of MDA because of SMB ingestion suggests that free radicals may have a critical role in these changes.