bluuebunny/crossref_metadata_2025 huggingface dataset:
A Combined Method of Two-model based on Forecasting Meteorological Data for Photovoltaic Power Generation Forecasting
Authors: Zhang Xiao , Shen Runjie , Wang Yiying
Published: September 2020

Under the background of the continuous development of photovoltaic power generation technology, accurate prediction of photovoltaic output power has become an important subject. In this paper, a combined method of two-model based on forecasting meteorological data for photovoltaic power generation forecasting is proposed. To solve the problem of the adaptability of a single model, two different models are used according to the different types of output power characteristics. The K-means clustering algorithm is used to classify different weather types according to the historical meteorological data. After predicting the irradiance and temperature of the period to be predicted and classifying the period into different types, the photovoltaic output power is predicted by a suitable model. The two prediction models are the Wavelet- Decomposition-ARIMA model and EDM-SA-DBN model, which are suitable for periods with larger and smaller fluctuation amplitude of photovoltaic output, respectively. Wavelet decomposition can refine the data with large fluctuations on multiple scales, make the data smooth, and improve the prediction accuracy of the Autoregressive Integrated Moving Average model (ARIMA). The Deep Belief Network (DBN) can effectively process a large number of complex data and deep mining the data features. While the empirical mode decomposition (EMD) can decompose the more stable data and amplify the details in the signal as much as possible. Meanwhile, the simulated annealing algorithm (SA) can avoid the network falling into a local optimal solution and improve the prediction accuracy. This paper uses a large number of photovoltaic power station data for experimental verification. The results show that this combined model has high accuracy and generalization ability.
Hierarchical and Droop Method for DC Micro-grid Bus Voltage under Isolated operation
Authors: Yan Xiangyang , Zheng Ningkang , Kang Yilong , Qi Huanruo , Li Kai , Pei Haowei , Niu Kai
Published: September 2020

Nowadays, distributed generation technology is of great help to the efficient utilization of new energy. If the distributed power supply is connected to the DC micro-grid, it will be more secure and reliable. Therefore, it is necessary to control the voltage stability of the DC bus and ensure the balance of the source charge power of system to ensure the power supply quality and safety of the DC micro-grid. There are two operation modes of DC micro-grid: connected operation and isolated operation, and isolated operation control is the foundation and key of system-level control of DC micro-grid. To solve the problem of bus voltage fluctuation in isolated dc micro-grid, this study proposes a voltage hierarchical-droop control strategy for DC micro-grid, which can effectively improve the stability of the DC bus voltage. Last, this study builds the simulation model of DC micro-grid in the MATLAB/Simulink platform to verify the validity and feasibility of the proposed control strategy.
Design and Application of Transmission Line Intelligent Monitoring System
Authors: Xing Zengqiang , Cui WenpengCui , Liu Rui , Zheng Zhe
Published: September 2020

This paper presents a design method of intelligent monitoring system for transmission lines based on artificial intelligence technology. In this design method, a low-power artificial intelligence chip - LieYing A101 is used to design an intelligent recognition module to realize real-time target recognition on a terminal device. In order to solve the problem that the original image and the input image resolution of the intelligent recognition module do not match, this paper uses a sliding window and convolutional neural network design method, which solves the image resolution mismatch problem and improves the recognition accuracy. Finally, for the problem of excessive network model size, feature channel weight pruning and 8-bit quantization methods are used to compress the network model to less than 10M, and the recognition accuracy is not sharply reduced. After the test set test and actual scene use, the external force destruction target recognition accuracy of the transmission line channel is high; this meets the application needs of customers.
Judge the Extent of the Harm on Electric Cables Based on Optical Fiber Sensing Technology and Found a New Mechanism of Patrolling Electric Cables
Authors: Yang Xianjin , Ye Jingqing , Yao Guangyuan , Chi Junfeng , Du Jiali
Published: September 2020

The article comes up with a measure that uses fiber vibration sensing technology to avoid external intrusion harm on electric cables, dealing with the problem that buried cables are sometimes destroyed by constructions. This measure is based on dual Mach-Zehnder(M-Z) interference, and it makes use of power grids’ fiber-optic cables laid in the cable trench—along with the electric cables—as sensors. These sensors could monitor vibration near to optical cables and trench, and recognize the events that vibrate the cable, and finally judge the extent of the harm caused by the events. The article also try to find out a more reliable and more efficient mechanism of patrolling electric cables, which is based on the abovementioned measure.
Study on co-pyrolysis behavior of Shengli lignite and cron staw
Authors: Li Liang , Liu Muxin , Qin Yingyue
Published: September 2020

The co-pyrolysis performance of coal and biomass was studied and the influences of corn straw on Shengli lignite pyrolysis were discussed in this paper. The results show that corn straw has much higher activity and lower char yield than Shengli lignite during pyrolysis process. Release of moisture in blends were more occur than individual pyrolysis of Shengli lignite and corn straw. Weight loss of experimental value was lower than that of calculated value in blends. The pyrolysis process of Shengli lignite was remarkably affected by adding corn straw. There exists positive synergistic effect between Shengli lignite and corn straw in co-pyrolysis process. Corn straw could reduce the pyrolysis activation energy of SL dramatically above 350 oC.
Research on the application of block chain technology in electricity trading system
Authors: Hao Qingli , Mi Ning , Qiao Ning , Zhang Chao , Li Can , Li Qiang , Chen Jie , Tian Hongjie
Published: September 2020

As the technical basis of Bitcoin, block chain has the characteristics of decentralization ， openness and transparency. In order to promote the development of security and openness of power trading system and solve the trust problem among participants in power market，a new research direction of power trading method based on block chain is proposed. Therefore，this paper outlines the block chain，explains the definition and characteristics of block chain in detail，discusses the application of block chain in power trading system，and summarizes the challenges faced by block chain technology in power trading system.
Study on critical liquid-carrying flow model in inclined Wells
Authors: Huang Quanhua , Lin Xingyu , He Yunjun , Wang Chengyin , Hu Yi , Ding Hongjun , Jiang Jian , Li Jian
Published: September 2020

It is very important to calculate the critical liquid-carrying flow for gas well.In this paper, an ellipsoid droplet model is established. By analyzing the droplet force in the inclined well and comprehensively considering the droplet drag force, gravity force, friction force, buoyancy force and supporting force, the general formula for calculating the critical liquid carrying flow is obtained. By using the reasonable formula of gas-liquid interfacial tension and The Formula of Weber number, the critical liquid carrying flow of gas well is verified.
A Structure Parameter Design Method of DD Coils to Optimize
Coupling Performance and Misalignment-tolerant Ability
Authors: Zhang Wei , Wang Fusheng , Guo Juanjuan , Ye Longfeng
Published: September 2020

Aiming at the problems of weak coupling performance and poor misalignment-tolerant ability of the magnetic coupling structure of electric vehicle wireless charging system, this paper proposes a coil structure parameter design method. This paper analyzes the relationship between the system characteristics and the coupling coefficient of the wireless charging system based on the dual LCC resonant compensation network. Then, based on the analysis of the structure parameters of DD coils, a structure parameter design method to optimize coupling performance and misalignment-tolerant ability is proposed. Finally, the ANSYS MAXWELL 3-D finite element model of the DD magnetic coupling structure is built, and the validity and feasibility of the proposed design method are verified by simulation. Under the design method of coil structure parameter in this paper, the magnetic coupling structure can achieve excellent coupling performance and misalignment-tolerant ability.
Optimal Strategy of Triple Phase Shift Transient DC Bias for Dual Active Bridge DC-DC Converter
Authors: Zhai Jingyu , Wang Fusheng , Ye Lizhong , Li Rui
Published: September 2020

Under the traditional phase shift control, dual active bridge DC-DC converter (DAB) has a
transient bias on the inductance current when the phase shift ratio changes suddenly, which leads to increase
in the current stress of switch tubes and even unidirectional saturation of the transformer. All those will
affect the stable operation of the converter. This paper focuses on quantifying the transient DC bias model
on the control of triple phase shift when phase shift ratios change, and then the strategy proposed by the
paper can eliminate the DC bias within one switching period and reduce current stress and response time by
adjusting the drive signal during the transient transition process. Finally, the proposed strategy is verified by
simulation results from Matlab/Simulink software.
Leukocyte recognition algorithm in leucorrhea microscopic images based on ResNet-34 neural network
Authors: Wan Xiuchao , Wang Zhiyong , Kong Guanghui , Xue Fengjun
Published: September 2020

Automatic leucocyte recognition for leukorrhea microscopic images is a digital image processing technology in the field of machine learning. The existence and quantity of leukocytes in leucorrhea microscopic image is an important sign and basis to judge the inflammation of vagina or cervix. Therefore, the recognition and count of leucocyte is an effective means to evaluate the condition of the disease. To solve the problem of low efficiency of leucocyte recognition in traditional artificial microscopy, this paper proposes an automatic recognition algorithm based on ResNet-34 neural network. Firstly, Canny edge detection algorithm based on genetic algorithm is used to extract the foreground target in the leucorrhea microscopic image. Secondly, the leucocyte target is selected according to the connected region and boundary rectangle parameters of the foreground target. Finally, ResNet-34 neural network is applied for the classification of leukocytes. Experiments show that the recognition accuracy of leukocytes in leucorrhea microscopic image is 92.8%, and the recall is 97.1%, which is higher and better than other methods.
Off-gas emission response mechanism in aerobic composting of sewage sludge: A review
Authors: Lu Yulan , Dai Yu , Qin Haiguang , Li Jun , Zhang Jun
Published: September 2020

In recent years, sludge output has increased rapidly with the dramatical growth of sewage treatment capacity. As a typical technology to treat organic solid waste, composting combined with land utilization is a wide-used to deal with sewage sludge. However, the off-gas emission, which includes odors and greenhouse gas, still is a ubiquitous problem in the composting industry. In this study, we reviewed the findings about this topic in the last decades. It was summarized that what was the emission mechanism of off gas and which are the key factors during aerobic composting of sewage sludge. The off-gas emission is corresponding to the anaerobic-region distribution in matrix, which is intensively affected by the obstructed gas region in matrix and physicochemical properties of the matrix particle. And some suggestions and prospects for future research are put forward to provide a reference for solving the off-gas emission problem of aerobic composting of sewage sludge in China.
Dynamic overcapacity modelling of early warning system for phosphorus fertilizer industry in China
Authors: Hao Li , Binlin Li , Jun Qin
Published: September 2020

In recent years, due to significant overcapacity in China’s phosphorus fertilizer industry, the pressure of industrial capacity reduction issue has been existing for a long time. The study contributes to establish a dynamic early warning system of overcapacity to provide meaningful insight for optimizing managerial policies of phosphorus fertilizer industry in China. The dynamic early warning system includes a novel and comprehensive evaluation model, and the commonly used entropy method is applied to effectively demonstrate the degree of overcapacity. Then, the GM (1,1) grey model proposed provides future production scenarios. Several useful conclusions can be obtained. First, the overcapacity of phosphorus fertilizer has been existing for a long time and is characterized by periodicity, and more obviously, overcapacity deteriorate significantly in 2011 and 2015. Second, the greater threat would be the excessive growth and low utilization rate of new capacity of production, and the higher volatility of phosphorus fertilizer price but relatively low profit for phosphorus companies. Third, the significant increase of raw material price, labor and transportation cost and financing cost will restrict the development of the overall industry in the future, and we highlight the more comprehensive policies to consider the uncertainties in the overcapacity issue in the long term.
Will environmental information disclosure bring economic inflow to enterprises? —— Based on the investigation of audit fees
Authors: Chen Ping
Published: September 2020

With the gradual deterioration of climate and environment, countries are becoming increasingly vigilant and repulsive to the economic development mode at the cost of energy consumption. It has become a new development trend to seek new alternative energy sources and pursue green and environment-friendly sustainable development mode. Environmental protection behaviors are generally considered to have positive external effects. This paper examines whether the environmental protection behaviors of A listed company have positive effects on the company based on the data related to environmental information disclosure from 2014 to 2017, and also examines the attitude of external supervision represented by independent auditing towards the company’s environmental protection behaviors. It is enlightening to encourage listed companies to save energy and protect the environment.
Spatiotemporal Variation of Pb Content Source Transportation in Jiaozhou Bay
Authors: Yang Dongfang , Zhu Hong , Zhang Longlei , Wang Qi , Li Haixia
Published: September 2020

Based on research data of the Jiaozhou Bay waters in May, August, and October 1992, the current transportation process and the various sources of Pb contents in the Jiaozhou Bay water body were studied. According to the Yang Dongfang migration law of the content, the results show that: after the ocean current with high levels of Pb content enters the Jiaozhou Bay, spatial change process of the sources carrying Pb content in May, August and October is shown with the transportation of the ocean current. Also, the model block diagram is used to reveal the change process of Pb content imported by ocean currents into the waters of Jiaozhou Bay. The location, magnitude, type, and time of the four sources of Pb content in the waters of Jiaozhou Bay were determined, which are the transportation of ships and terminals, surface runoffs, rivers, and offshore currents. Pb content of surface runoff transport is relatively low, and the transport time is short. Whereas Pb content of the ship terminal is increasing, and the time of transportation is also raising. And the content of Pb transported by rivers is the highest, and it has been transporting from land to sea nonstop throughout the year. Offshore currents carry a very high level of Pb content and constantly transporting it to the water body with low content of Pb. During the year, ships and terminals, land, and rivers were heavily polluted by Pb content, as well as the entire ocean. Among the rivers entering the sea around Jiaozhou Bay, there are four main ones: Haibo River, Licun River, Loushan River, and Dagu River. The sequence of Pb content transported by the rivers from high to low is listed as following: Licun River>Loushan River>Dagu River>Haibo River. The delivery time of Pb content in Licun River is the longer as delivery time in Haibo River, Loushan River and Dagu River is the same. Therefore, it is necessary to strictly control the Pb content from river transportation.
Experimental Study on Collimation Characteristics of an ECRH System with a 28GHz/50kW Gyrotron
Authors: Zhou Qing
Published: September 2020

In this paper, the collimation characteristics of an electron cyclotron resonance heating (ECRH)
system with a 28GHz/50kW gyrotron in EXL-50 are studied experimentally. Through using laser trackers
and designing matching tooling, test errors of horizontal distances and vertical distances between the
transmission line and the flange center are all within 1mm, which are less than 0.4% and 0.07% respectively.
In addition, online beam spot test with a 150 ms short pulse from a 28 GHz gyrotron also proves good
collimation characteristics of the ECRH system. Finally, spherical plasma is formed through injecting the
microwave to the vacuum chamber.
Numerical simulation of the effect of fault inclination on the sudden water of the fault bottom plate
Authors: Jia Xiao-Liang
Published: September 2020

The main reason for the frequent occurrence of water accidents on the bottom plate of the working surface near the mine fault in China is that the excavation activities cause the fault to activate and direct the pressure water of the aquifer. The distribution of ground stress fields and plastic regions under the influence of extraction disturbance spree is analyzed by using the flaC3D simulation software FLAC3D simulation software. The results show that the greater the inclination of the fault, the greater the shear stress and the normal stress at the fault level, and the deeper the activation range of the mining fault is larger than that of the shallow one ,and the small inclination positive fault is more likely to produce the fissure between the working surface base plate and the aquifer, and the small inclination positive fault should be left with a wider water-bearing coal column in the actual safety design. Using this software, the evolution of the stress field and plastic zone in the adjacent mining area is a preview, which is of great application value to prevent the surface plate burst water and determine the retention width of the fault waterproof coal column.
Interpretation of Singapore’s “Water Efficiency Labelling Scheme” System
Authors: Weizhe Chen
Published: September 2020

Water efficiency label is a kind of information label which provides necessary information for consumers’ purchase decision. As one of the earliest countries to implement water efficiency labeling program / Project in the world, Singapore’s "water efficiency labeling program" system has achieved remarkable water-saving effect for its own country, which has great reference significance for China’s water-saving management.
A standard sample determination method for the testing of smoke detectors and its application research
Authors: Wang Tingting , Wu Guoping , Zhang Pei , Zhang Dake
Published: September 2020

The stability of the standard sample plays a key role in the testing of the smoke detectors. A scientific and effective standard sample selection scheme is proposed in this paper. The repeatability and uniformity of the tested samples are evaluated before and after the environmental acceleration testing, and the most stable standard sample is obtained. At the same time, this paper explores the new application of the standard sample, which can be used in the calibration of the measuring ionization chamber (MIC). This work can greatly reduce the selection time and provide the standard samples for the laboratory of the smoke detectors testing which is scientific and reliable. At the same time, the difficult problem of the calibration of the measuring ionization chamber (MIC) is solved here.
Overexpression of YAP and miR-130a is closely related to pulmonary hypertension in congenital diaphragmatic hernia
Authors: Liao Junzuo , Liu Wenying , Zhang Libin , Li Qin , Hou Fang
Published: September 2020

Purpose: The aim of this study was to investigate the expression of YAP and miR-130a in the normal lung tissues and CDH lung tissues through the rat model of CDH, and preliminarily explored the relationship between YAP, miR-130a and CDH. Methods: Pregnant rats were divided into two groups: control (n = 5) and CDH (n = 5). A single oral dose (125 mg/kg) of nitrofen was administered to pregnant rats on embryonic day (E) 9.5 to induce CDH. All fetuses were acquired by cesarean delivery on E21.5. Fetuses with diaphragmatic hernias in the CDH groups were chosen for analysis. Lung weight (LW) and body weight (BW) were recorded and histologic evaluations, image analysis, western blot analysis and PCR were performed after lung processing. Results: Five female rats in the control group produced 76 fetuses without CDH. CDH was observed in 49 of 72 rat fetuses in the CDH group. Pulmonary hypoplasia and vascular remodeling were observed in the CDH group. YAP expression in the lungs was markedly increased in the CDH group compared to the control group (P = 0.001). However, there was no significant difference in the phosphorylation level of YAP (P = 0.113) between the two group. YAP mRNA and miR-130a expression in the lungs were markedly increased in the CDH group compared to the control group (P = 0.01, P = 0.002). Conclusion: A relative increase YAP activity and miR-130a expression in the CDH rats may be associated with increased pulmonary vascular resistance. The role of the feedback mechanism between YAP and miR-130a playing in the CDH-associated pulmonary hypertension deserves further study.
Review of the Combination Strategies Used in Anti-PD1/PD-L1 Monoclonal Antibody Treatment
Authors: Cheng Jiaxing
Published: September 2020

In recent years, the research achievements of immunotherapy were outstanding, especially in the field of cancer treatment. At present, the major breakthroughs have been made in the research of immunotherapy based on programmed death receptor 1 (programmed death 1, PD-1) or programmed death ligand 1 (programmed death-ligand 1, PD-L1) immune checkpoint blockage. The successful application of anti-PD-1/PD-L1 mono clonal antibody in various clinical trials has showed its remarkable potential in caner immunotherapy. However, the results were not always satisfactory that treatment results often show large individual differences between patients, and it’s usually only a small part of patients would respond the treatment. Thus, combination therapy has become a new research focus in anti-PD-1/PD-L1 blockage-based therapy strategy development. This article will review the combination strategies of anti-PD-1/PD-L1 mAbs treatment and discuss the development and the trend of combination immunotherapy.
Systematic Analysis of Clinical Curative Effect of Acupuncture on Children with Cerebral Palsy Movement Disorder
Authors: Hou Yujin , Jie Xiaosu , Guo Xin , Zhang Yingying , Shi Hua , Lou Yuanjun
Published: September 2020

Objective: To explore the effect of applying acupuncture on children with cerebral palsy dyskinesia. Methods: Research work was carried out in our hospital. The work was carried out from November 2018 to November 2019. A total of 100 patients were selected, all of whom were children with cerebral palsy, accompanied by dyskinesia. They were randomly divided into two groups, and were given conventional rehabilitation training and acupuncture treatment respectively, named the control group and the experimental group, and the clinical efficacy of the two groups of patients was analyzed. Results: There was no significant difference in the MAS scores of the two groups of children before treatment, which was expressed as P> 0.05. After treatment intervention, the scores of the two groups of children were improved, in contrast, the improvement effect is more significant for the experimental group, the data difference is large, P <0.05, which is significant. The treatment effective rate of the children in the experimental group was 92.00%, and the treatment effective rate of the children in the control group was 76.00%, there is a big difference between the two groups of data, P <0.05, which is significant. Conclusion: The application of acupuncture and moxibustion therapy in children with cerebral palsy movement disorders can improve the adverse symptoms of children and promote the recovery of patients, which has positive significance for clinical development.
Therapeutic Effect of Xingnaotongdu Acupuncture Combined with Huoxuetongluo Decoction on Patients with Post-Stroke Cognitive Dysfunction
Authors: Ding Ruicong , Zhou Shenghua
Published: September 2020

To investigate the efficacy of Xingnao Tongdu Acupuncture Combined with Huoxue Tongluo Decoction in the treatment of post-stroke cognitive dysfunction. Eighty-eight patients with post-stroke cognitive dysfunction were enrolled in our hospital from July 2016 to July 2018. The patients were randomly assigned to a total of 44 patients. The control group was treated with conventional western medicine. The experimental group was treated with Xingnao Tongdu Acupuncture Method + Huoxue Tongluo Decoction on the basis of the control group for 1 month. Statistical comparison was performed between the two groups before and after treatment (NCSE), serum heat shock protein (HSP70), cortisol (Cor), and daily living ability (ADL). Compared with the control group, the NCSE scores of the experimental group were higher after treatment (P<0.05). Compared with the control group, the serum HSP70 level was higher and the Cor level was lower (P<0.05). The ADL score of the experimental group was higher after treatment (P<0.05). Xingnao Tongdu Acupuncture Combined with Huoxue Tongluo Decoction in the treatment of post-stroke cognitive dysfunction can regulate serum Cor and HSP70 levels, improve cognitive function and improve daily living ability.
General factors that influence the immune responses in children
Authors: Hee Ha Eun
Published: September 2020

The research paper is written with the aim to identify different factors that influence children’s immune responses. Five theories are explored on children’s susceptibility to certain diseases and their lack of susceptibility to others. Aspects that are explored in this paper are children’s levels of immunoglobulin production, their cytokine production amount, their underdevelopment of receptors, their asymptomatic nature to certain diseases, and environmental factors. Through exploring different studies on child immunity, the paper concludes that the susceptibility of children to diseases largely depends on the type of disease and the individual’s immune system. Future research is clearly required to identify a smaller scope of the factors that influence children’s immune responses to provide a more detailed reasoning in the causes of children’s proneness to certain diseases and their lack of susceptibility in others.
Clinical Effect of Knee Arthroscopy Combined with Liuwei Gubi Pill in Treating Middle-aged and Elderly Patients with Degenerative Meniscus Injury
Authors: He Zike , He Kaifei , Wang Shangzeng
Published: September 2020

Objective: To study the effect of knee arthroscopy combined with Liuwei Gubi Pill on degenerative meniscus injury in middle-aged and elderly patients. Methods: A total of 92 middle-aged and elderly patients with degenerative meniscus injury who were treated in our hospital from August 2018 to February 2020 were collected. They were divided into two groups by envelope lottery. Knee arthroscopy was used for the reference group of 46 patients, and they were guided to perform joint function exercises after surgery; 46 patients in the experimental group took Liuwei Gubi Pill on the basis of the reference group, and compared the efficacy of the two groups. Results: The total effective rate of treatment in the experimental group was 97.83%, which was higher than the reference group’s 84.78%. The experimental group’s VAS score at 1st month, 2nd month, and 3rd month after surgery was lower than that in the reference group. The Lysholm score of the experimental group at 1st month, 2nd month, and 3rd month after operation was significantly higher than that of the reference group, and the data of the two groups was compared by P<0.05. Conclusion: The treatment of middle-aged and elderly patients with degenerative meniscus injury by knee arthroscopy combined with Liuwei Gubi Pill has an ideal effect, which can alleviate postoperative pain and benefit the recovery of knee function.
Effect of “Modular” Nursing Intervention on the Therapeutic Effect of Ranoxifene on Postmenopausal Osteoporosis
Authors: Guo Yang , Sun XiaoJie , Tai Miao , Liu Fang , Liu XiaoWei , Yao Jie
Published: September 2020

the purpose of this study was to explore the effect of “modular” nursing intervention on Ranoxifene in the treatment of patients with postmenopausal osteoporosis. A total of 108 patients with postmenopausal osteoporosis who were accepted by the Department of Orthopaedics in our hospital were selected as the research objects. According to the random number table method and they were divided into two groups (the intervention group and the control group), 54 cases in each group. The control group was given routine care, while the other was given “modular” interventional care. The patient satisfaction, adverse mood changes and quality of life changes in the two groups was observed in the treatment. The results of this study showed that the nursing satisfaction of the patients in the intervention group was significantly higher than that in the control group; however, the negative emotion of the two groups of patients after care were lower than that before the care, and the degree of reduction in the intervention group was significantly higher than that of the control group; the life quality of patient in the two groups was improved than before nursing, and the degree of improvement in the intervention group was significantly higher than that in the control group. Therefore, the clinical application of Raloxifene in the treatment of postmenopausal osteoporosis patients with “modular” nursing intervention can improve patient satisfaction, relieve negative emotions, and improve quality of life.
Automatic segmentation and recognition of red and white cells in stool microscopic images of human
Authors: Kong Guanghui , Wang Zhiyong , Wan Xiuchao , Xue Fengjun
Published: September 2020

Aiming to solve the problem of low efficiency in manually recognizing the red and white cells in stool microscopic images, we propose an automatic segmentation method based on iterative corrosion with marker-controlled watershed segmentation and an automatic recognition method based on support vector machine (SVM) classification. The method first obtains saliency map of the images in HSI and Lab color spaces through saliency detection algorithm, then fuses the salient images to complete the initial segmentation. Next, we segment the red and white cells completely based on the initial segmentation images using marker-controlled watershed algorithm and other complementary methods. According to the differences in geometrical and texture features of red and white cells such as area, perimeter, circularity, energy, entropy, correlation and contrast, we extract them as feature vectors to train SVM and finally complete the classification and recognition of red and white cells. The experimental results indicate that our proposed marker-controlled watershed method can help increase the segmentation and recognition accuracy. Moreover, since it is also less susceptible to the heteromorphic red and white cells, our method is effective and robust.
Detection of Wampee Damage based on Hyperspectral Imaging Technology
Authors: Qiu Wen-Wu , Su Wei-Qiang , Cai Zhao-Yan , Dong Long , Li Chang-Bao , Fang Wei-Kuan , Liu Ye-Qiang , Xiao-Mei Wang , Huang Zhang-Bao , Qiao Jian
Published: September 2020

Wampee is one of the characteristic fruits in southern China, and its brittle and thin skin can easily be damaged. In this study, principal components analysis (PCA) and minimum noise fraction (MNF) analysis were carried out on the two wampee varieties by hyperspectral imaging technology, and 680nm was determined to be the optimal characteristic wavelength. The accurate recognition rate obtained from PCA algorithm for wampee samples of two varieties was about 83.75%, and that obtained from MNF algorithm for two variety samples was 85%. It was indicated that the wampee damaged can be identified more accurately and effectively by MNF based on hyperspectral imaging technology
Effects of Microstructure Characteristics of Cortical Bone on its Microcrack Propagation
Authors: Liu Yu-xi , Li Ai-hua , Li Yan-hua
Published: September 2020

Scanning electron microscope (SEM) was used to observe and analyze the microstructure of the cross section of cortical bone. The observation results illustrated that the cortical bone is composed of cylindrical osteons and interstitial bone between osteons, and the osteon are unevenly distributed. Based on the microstructure characteristics of cortical bone, three types of cortical bone mesoscopic analysis models were established. Then, the extended finite element method (X-FEM) was used to simulate the microcrack propagation process in bone. The simulate results show that the crack initiation strain of the two-phase model is 19.1% larger than that of the single-phase model, and the three-phase model is 57.8% larger than that of the two-phase model, which demonstrated that the osteons and cement line can significantly enhance the crack initiation strain of bone. In addition, under the same boundary conditions, the model with cement line can effectively change the propagation path of microcrack and prevent the propagation of crack. Therefore, the cement lines in cortical bone can effectively increase the fracture resistance of bone and enhance the fracture toughness of cortical bone.
What are the Prevalence and Risk Factors of Alzheimer’s Disease in China and the United States?
Authors: Xu Yiyang
Published: September 2020

Dementia, especially Alzheimer’s dementia, which occupies more than 60% of total dementia cases, has become one of the most significant health problems in the world due to its increasing global prevalence, irreversible pathology, and rising social and economic costs. In this research, the author compared Alzheimer’s disease (AD) prevalence in China and the United States and found the common pattern of its epidemiology. Apart from the quantitative analysis, this research also identifies the pathophysiological, socioenvironmental, and other risk factors of Alzheimer’s disease by qualitative desk research. It was found that the risk factors related to or controlled by genes such as Single Nucleotide Polymorphisms (SNPs) have more influential effects on Alzheimer’s disease onset than the socio-environmental factors. Some socioenvironmental factors such as level of education reflecting the brain activity of a person are also correlated with Alzheimer’s disease prevalence. This disease is caused by an interplay of numerous factors, so there needs to be further investigations into its mechanisms as well as the combination therapy.
CRISPR/Cas9 high-throughput screening in cancer research
Authors: Liu Zhuoxin
Published: September 2020

In recent years, CRISPR/Cas9 technology has developed rapidly. With its accurate, fast, and simple editing functions that can achieve gene activation, interference, knockout, and knock-in, it has become a powerful genetic screening tool that is widely used in various models, including cell lines of mice and zebrafish. The use of CRISPR system to construct a genomic library for high-throughput screening is the main strategy for research of disease, especially tumor target gene research. This article reviews the basic principles and latest developments of CRISPR/Cas9 library screening technology strategies to improve its off-target effect, the basic workflow of library screening, and its application in tumor research.
Influence of Exercise Prescription on Subjective Well-being and Sleep Quality of Trailing Elderly Females
Authors: Wei-wei Zhang , Jun-mei Xia , Ling Yu
Published: September 2020

The influence of exercise prescription of different sports on the subjective well-being level and sleep quality of elderly females was studied. The results show that the exercise prescription can all improve the subjective well-being and sleep quality of the trailing elderly females. The traditional sports on the improvement of positive emotion and experience are obviously superior to aerobic sports. The exercise prescription of traditional sports and aerobic sports is significantly higher than fitness-walking sports on promotion of sleep quality and sleep efficiency.
Regulation of Caenorhabditis Elegans model in Alzheimer’s Disease
Authors: Jing Yuxuan
Published: September 2020

Alzheimer’s disease (AD) is affecting numerous families and individuals around the world nowadays, as the exact reason is still undetermined. At this stage, developmental treatment displays a particularly significant role in relieving symptoms for the patients. Currently, the two most well-known factors that have impacts on the diagnosis of AD are the plaques and tangles formed from amyloid-beta and tau protein. Modelling for Alzheimer’s disease is essential in understanding targeted aspects of the disease, while Caenorhabditis elegans (C.elegans) was chosen as a pivotal model. C.elegans presents dramatic priorities using orthologs for the study of AD, especially in examining the formation of the deposits and the regulations of specific gene expressions that result in this abnormality. This review discusses the properties, which C.elegans shows on the study of AD, and the achievements that have been approached using this model, as well as what other models are being tested by scientists. Properties of other models, which can overwhelm C.elegans, as well as the expectations for future modelling systems on AD are examined as well.
Use thermophysical property to quantify state of HIFU treatment for VLS
Authors: Feng Sui , Qu Yingjie , Meng Yuquan , Zheng Jinjin
Published: September 2020

The aim of this study is to evaluate the performance of ADT methods in grading the effectiveness of HIFU treatment for VLS. High-intensity focused ultrasound has been identified as a promising treatment modality for vulvar lichen sclerosus, a common inflammatory disorder associated with an increased risk of developing vulvar carcinoma. With small probe on extensive VLS parts, the therapy was sometimes uneven, thus the total doses of HIFU machine couldn’t indicate the curative effect at each part. The current therapeutic effect was based on symptoms and skin appearance after 3 months, which was time-consuming. Until now, there has been no immediate quantitative assessment method of HIFU therapeutic response for VLS. In our study, active dynamic IR thermal (ADT) was scheduled to undergo HIFU therapy before and after treatment. The thermal time constant was calculated based on ADT images measured both before and after HIFU treatment. In the result of pig phantom measurements, with each part approximately the same thermal time constant before HIFU treatment, the change of thermal time constant was strictly positively associated with HIFU dose onto each part. This study demonstrates the clinical potential of ADT in fast and effective quantify state of HIFU treatment for VLS.
Suger-coated pillararenes for drug delivery applications
Authors: Chenglin Zhang , Jihao Su , Hongxia Zhao
Published: September 2020

Supramolecular drug delivery systems (SDDSs) provide a useful platform for smart and functional drug carriers owing to their high selectivity towards various guest molecules and stimulus-responsive properties. Pillar[n]arenes represent a new generation of macrocyclic hosts with unique structures and chemical properties. In recent times pillar[n]arenes have attracted considerable attention as ideal scaffolds for the construction of SDDSs. Since sugar functionalized pillar[n]arenes have good water solubility and excellent biocompatibility, they have been widely applied in supramolecular systems construction, such as nanoparticles, vesicles, and gels by non-covalent interactions, so as to meet the requirements of their applications in biomedicine. These SDDSs present good responsiveness, not only realizing targeted delivery and controllable release of drugs, but also improving drug solubility and reducing its toxic and side effects. Here, according to the different structure of the assembly, the SDDSs constructed by the sugar functionalized pillar[n]arenes are summarized, and the development prospect of the system is prospected.
Influence of sensory integration training on mental mobility of elderly people with MCI
Authors: Hongmei Zhang
Published: September 2020

With increasing age, in general, the human intelligence level is gradually decreasing. Mild cognitive impairment, abbreviated as MCI, is a type of cognitive dysfunction that commonly occurs in the aged and balances the normal state of aging and senile dementia. Mild cognitive impairment is easily converted to Alzheimer's disease elderly if it is not controlled in time. In order to study how to better train the aged in MCI and design related training systems to help the aged to delay the MCI's circle, a sensory comprehensive training is conducted to study on the impact of mental mobility in the old MCI in this article. The final research results show that sensory integration training can improve the state of mental mobility in MCI elderly by strengthening the training of MCI elderly sense andtouch.
Study on the Antilipidemic Activity of Artemisia Annua Aqueous Extract
Authors: Tao Ali , Feng Xuehua , Song Zurong , Hu Bo , You Huan , Wang Ruilin
Published: September 2020

Artemisia annua is an annual herb, which is a traditional Chinese medicine in China. The high water soluble artemisinin derivative extracted from Artemisia annua is Artemisia annua water extract. In this experiment, the modeling method is used, and the Artemisia annua water extract is used alone or in combination with other lipid-lowering drugs. Finally, the results showed that the effect of the combination of drugs was better than that of Artemisia annua water extract alone, and the effect of the drug ratio of 1:1 was the best. It can significantly reduce the content of triglyceride in serum and cholesterol, increase the ratio of H/L, and show a good synergistic effect.
Research on Targeted Thermal Effect of Molybdenum Disulfide Nanosheets Modified by Nucleic Acid Aptamers
Authors: pang Bo , Jin Lihong , Wang Liying
Published: September 2020

In this paper, the surface of molybdenum disulfide nanosheets synthesized by hydrothermal method was modified with bovine serum albumin (BSA) and nucleic acid aptamers in order to construct a photothermal system with high target recognition, stable size, good biocompatibility and low toxicity Nano material molybdenum disulfide; Under 808 nm laser irradiation, suitable functionalized molybdenum disulfide nanosheets can produce singlet oxygen at an effective concentration for photodynamic therapy, and at the same time, photothermal therapy can also be used to achieve synergistic therapy and the therapeutic effect is more excellent. This shows that such functionalized molybdenum disulfide nanosheets have excellent therapeutic effect and great potential in tumor treatment.
Fungal screening and phylogenetic tree construction
Authors: Zhou Jianyang
Published: September 2020

The second-generation sequencing technology has achieved rapid development in recent years. It has the advantages of fast speed, high accuracy and low cost compared to the former sequence, so it has a widely application. Marine fungi are important sources of active Marine natural products. Due to the differences in the thermodynamic properties of land and sea and the concentration of salt oxygen, it has a great potential to produce new bioactive substances. Nowadays, scientists isolate and identify a large number of secondary metabolites with novel structures which is from marine fungi, and these compounds show excellent biological activities. For example, some are potential drugs to treat cancer. In order to search for new fungi, this article used a series of biological methods to isolate and study the bacteria isolated from huimin wharf and determine their specific species. And this paper also uses 18S rDNA to analyse the gene sequence and construe the phylogenetic tree.
Short-term Study of Bushen Jiangu Decoction Combined with PVP in the Treatment of Elderly Patients with Osteoporotic Thoracolumbar Vertebral Compression Fracture
Authors: Yue Zongjin , Liu Ruyin , Yu Lu , Zhang Liuqiao , Feng Zhongkai , Wang Xinli
Published: September 2020

To investigate the clinical effects of Bushen Jiangu Decoction combined with percutaneous vertebroplasty (PVP) in the treatment of elderly patients with osteoporotic thoracolumbar vertebral compression fracture (OVCF). Seventy-four elderly patients with OVCF were enrolled in our hospital and randomized by digital table method, 37 cases each. The control group received PVP treatment, and the observation group was treated with Bushen Jiangu Decoction on the basis of PVP treatment. Cobb angle, bone mineral density, Oswestry dysfunction index questionnaire (ODI) score, and visual analogue scale (VAS) were compared before and after treatment. After treatment, the Cobb angle of the observation group was smaller than that of the control group, and the bone density was higher than that of the control group (P<0.05). The ODI score of the observation group was lower than that of the control group after treatment (P<0.05); 1 month and 3 months after treatment, the VAS score of the 6-month observation group was lower than that of the control group (P<0.05). Bushen Jiangu Decoction combined with Western medicine in the treatment of elderly patients with OVCF can restore Cobb angle, increase bone density, reduce postoperative pain and improve thoracic and lumbar spine function.
Research and Application of Key Techniques for Preserving and Sterilizing Preprocessed Food Processing
Authors: Tianfei Dong
Published: September 2020

During the development of pre-made and conditioned foods, the corresponding recipes and process requirements should be met, large-scale production work should be performed in the central kitchen, and then distributed to the terminal stores, so that the conditioned foods become more popular. Based on previous work experience, this paper summarizes the research status of key technologies for preserving and sterilizing pre-processed foods. At the same time, this article discusses the key technical application content of pre-conditioned food processing quality and sterilization from four aspects: the application of ultra-high pressure technology, the prevention and control of common microorganisms, the application of tea polyphenols, and the development trend of pre-conditioned food.