bluuebunny/crossref_metadata_2025 huggingface dataset:
Qualitative & Quantitative Assessment of Human Islets Using Dithizone (DTZ) v2
Authors: Islet Phenotyping Program (HIPP) of the IIDP Human
Published: November 2020

This Standard Operating Procedure is adapted from the work of the 'National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities'' following the SOP cited in the document 'Purified Human Pancreatic Islet: Qualitative and Quantitative Assessment of Islets Using Dithizone (DTZ) – Standard Operating Procedure of the NIH Clinical Islet Transplantation Consortium' This SOP defines the assay method used by the Human Islet Phenotyping Program (HIPP) for quantitative and qualitative determination of the Purified Human Pancreatic Islet product, post-shipment, manufactured for use in the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)-sponsored research in the Integrated Islet Distribution Program (IIDP). Dithizone (diphenyl thiocarbazone; DTZ) is an organic chemical that chelates the zinc in the insulin granules present in the beta cells of the pancreatic islets. The islet cells are stained red while the acinar cells remain unstained. DTZ staining is used as a lot release and as an in-process assay: (i) Lot release testing: DTZ staining is used to identify islets and to determine the quantity and quality of the final islet product. Islet quantity is expressed as the number of islet equivalents (IEQ), which is calculated based on the number and diameter of the islets present in the preparation, mathematically corrected for islet volume. (ii) In-process testing: DTZ staining is used to identify islets and to assess the effectiveness of the digestion, isolation and purification processes. The quality of the preparations is expressed as percent islet purity, and percent trapped islets. Islet quantity (IEQ) is also assessed.
Çocukluk Çağı İmmün Trombositopenik Purpura (İTP) Hastalarının Yaş Gruplarına Göre Değerlendirilmesi
Authors: PARLAR Muhammed , ACIPAYAM Can , DİNÇER Serpil , GÜLLÜ Ufuk Utku , ÇOBANUŞAĞI Mustafa , MARAŞLI Hüsnü
Published: November 2020

Amaç: İmmün trombositopeni (İTP), artmış kanama riskine neden olabilen, trombosit sayısının azalması ile karakterize otoimmün bir hastalıktır. Çalışmamızda İTP hastalarının yaş gruplarına göre değerlendirilmesi amaçlandı.
Gereç ve Yöntemler: Eylül 2014 ile Ocak 2019 tarihleri arasında İTP tanısı alan hastalar 3-24 ay, 2-10 yaş ve 10-18 yaş olarak gruplandırıldı. Gruplar demografik özelliklerine, laboratuvar verilerine, tedavi şekillerine, tedaviden 12 ay sonraki trombosit sayılarına, tedavi direncine ve kronikleşme durumuna göre karşılaştırıldı.
Bulgular: Çalışmaya İTP tanısı alan 104 hastanın 95’i dahil edildi. Hastaların 28’i 3-24 ay, 41’i 2-10 yaş ve 26’sı 10-18 yaş aralığındaydı. Hastalar IVIG, steroid ve IVIG ile steroid birlikte verilerek tedavi edildi. Yaş ilerledikçe sadece steroidle tedavi sıklığının arttığı görüldü (p=0,030). Kronikleşen hasta sayısı 37 idi. Hastalığın 10 yaş üzerinde görülmesi (p<0,001), hastanın tanı anındaki trombosit sayısının ≥20 x10³/mm³ olması (p=0,002) ve hastalara sadece steroid tedavisi verilmesi (p<0,031) tedavi sonrası kronikleşmeyi etkileyen ve istatistiksel olarak anlamlı olan risk faktörleriydi.
Sonuç: Çalışmada hastaların 54’ü erkekti. Hastalar 2-10 yaş grubunda daha fazlaydı. Hastaların 37’si kronikleşti. 10-18 yaş grubunda tedaviye direnç ve kronikleşme durumu daha fazlaydı.
Assessment of a cracked reinforced concrete supporting structure for a converter in a steel melting shop through non-destructive testing and a statistical approach – a case study
Authors: Das D , Debbarma S R , Bouri D , Banerjee S , Chatterjee S
Published: November 2020

The subject of this paper is the occurrence of cracks and other types of damage, such as delamination of the reinforcement cover, carbonation, porosity, etc, which have occurred in a reinforced concrete supporting structure for a converter in a steel melting shop in India. The structure
consists of two thick reinforced concrete walls on which the converter rests. Converters are used in a steel melting shop for blowing oxygen through hot metal and steel is produced through a reaction with carbon, silicon, phosphorus, sulphur, etc. A scientific review of the existing non-destructive
test methods is carried out with reference to this case study and critical features of the testing process are described, which will help site engineers to correctly devise the test sequence and analysis procedure for assessment of the structures in specific critical conditions. Crack depth
is estimated by analysing test results based on the ultrasonic pulse velocity. The paper explains how appropriate selection of the method and basic parameters is essential for estimating the most accurate crack depth. Lack of understanding of the existing condition of the material of the structure
may lead to an incorrect interpretation of the test results. Further to this, a simple statistical procedure is described to identify significant cracks without detailed testing. The repair methodology and its specific features are also discussed in this paper. This case study on the assessment
of the converter supporting structure will help engineers to provide solutions for similar types of damaged structure found in industry.
Detection of localised flaws in small-diameter carbon steel tubes using multi-NDE techniques
Authors: Singh W Sharatchandra , Mukhopadhyay C K
Published: November 2020

This paper proposes multi-NDE techniques for enhanced and reliable detection of localised defects or flaws in small-diameter (19.05 mm outer diameter (OD) and 2.77 mm wall thickness (WT)) low-carbon steel tubes. Multi-NDE techniques comprising magnetic flux leakage (MFL), remote field
eddy current (RFEC) and the ultrasonic internal rotary inspection system (IRIS) are used to investigate the detectability and spatial resolution for the detection of localised flaws of different types and sizes, which simulate flaws generally formed in carbon steel tubes. The studies reveal
that the MFL and IRIS techniques detect 0.55 mm-deep holes and notches while the RFEC technique detects 1.11 mm-deep holes and 0.55 mm-deep notches. The IRIS technique is capable of resolving axial and circumferential holes (1 mm diameter and 1.39 mm depth) of 2 mm hole-to-hole separation,
while the MFL technique can resolve axial holes of 2 mm hole-to-hole separation but not circumferential holes. The RFEC technique can detect axial holes as a single hole but is unable to detect circumferential holes, resulting in no spatial resolution for the axial and circumferential holes.
Compared to the MFL and RFEC signals, IRIS readily discerns the spatial extent of the flaws with the possibility of sizing from the images. The study also reveals that the resolution capability of the IRIS technique is influenced by the speed of the turbine rotation inside the tube.
DERECHO Y GLOBALIZACIÓN: SIETE PUNTOS DE CONTACTO
Authors: Lascarro Castellar Diemer , Lascarro Castellar Carlos
Published: November 2020

El presente documento tiene como objetivo general explorar siete puntos de contacto entre el derecho y la globalización, para rastrear algunos impactos de este fenómeno en la ciencia jurídica. Se analizan entonces, conceptos como estado constitucional, la reestructuración del campo jurídico, el concepto de soberanía, sociedades de control, activismo judicial y algunas dinámicas neoliberales. Al final el documento cierra con unas conclusiones.
Factors affecting clinical referrals to the medical library
Authors: Kellermeyer Liz , Strand Matthew
Published: November 2020

Objectives: To determine why and when clinical care teams refer patients to the medical library.
Methods: A 2018 survey of clinical care teams at a research hospital measured awareness of library services available to patients, facilitators and barriers to referral, and likelihood of future referral. Spearman correlations were used to determine the strength of relationships between familiarity with the services and how often respondents referred those services. Referral rate distributions were compared between job type groups.
Results: Overall, self-reported referral rates were low. There was a marginally significant relationship between referral rate and job type (p=0.01), with providers having lower referral rates. There was a positive correlation between familiarity with library services and service referral frequency (rs=0.78 for combined data) and between current referral rates and likelihood of future referral (rs=0.43 for combined data, p<0.0001 for both). Among respondents who had never referred patients, the top reasons were lack of awareness of library services and uncertainty about how to make referrals.
Conclusions: The results suggest that lack of knowledge, rather than lack of interest and support, results in lower clinic referrals to the library. When providers are aware of the library they are referring patients, and those currently referring are likely to make future referrals. The qualitative responses show agreement, linking the lack of referrals to marketing and procedural insufficiencies (rather than distrust or dislike of the services), which indicates potential for increasing referrals by addressing these deficits. A streamlined patient referral system from clinic to library could be beneficial.
Case studies
Authors: Exner Nina
Published: November 2020

The inaugural column of Methods Moment focuses on the topic of case study methodology. Each Methods Moment column will present a brief, pratical overview of an issue in research methodology.
At the Feet of the Familiar
Authors: Affeldt Steven G.
Published: November 2020

My first substantive conversation with Stanley concerned Emerson. Having come to his work through my interests in Wittgenstein, ordinary language philosophy, and skepticism, I arrived at Harvard as a graduate student in the mid-1980s hoping to work with him on these kinds of concerns—the concerns that had guided much of my undergraduate studies at Berkeley. Since I had read Part Four of The Claim of Reason, I shouldn’t have been surprised to find that the center of Stanley’s philosophical concerns had shifted somewhat away from Wittgenstein and toward Romanticism (as well as, at that point, Hollywood melodrama). But I was surprised, and that surprise turned to disappointment and distress upon attending the first few meetings of a lecture course on Emerson that he offered early in my time as a student. While I found Stanley’s lectures interesting enough, I found Emerson all but entirely unreadable— often impenetrably obscure and, where not, ridiculously musty, pretentious, and overwrought. Since I wasn’t generally given to condemning authors I’d only begun to read—the philosophical virtue of the principle of charity had been deeply inculcated in me at Berkeley—I’m certain that my hasty and confident condemnation of Emerson was, whatever else, an expression of the kind of dismissiveness toward American philosophical thought that Stanley has diagnosed. Our first substantive conversation, then, consisted in his patiently responding to my embarrassingly uninformed, but firmly expressed, exasperation with Emerson. I can still hear Stanley’s voice as he assured me that he knew Emerson could be “hard to take.”
In Memoriam
Authors: Stone Abraham D.
Published: November 2020

I remember distinctly the moment I learned that David Lewis had died. It was during my years as a postdoctoral fellow, when I was more than a little isolated, and so it turned out to have been some time—months, maybe—since the event. I recall thinking: the world in which I thought I was living, during those months, turned out not to be the actual world, and so I turned out not to be the person I thought I was, but merely a counterpart of that person. And thus arose the half-formed thought (still only half-formed now, alas) that therein lay some insight into what is actually at stake in the conflict between counterpart theory and transworld identity.
Social Capital Dimensions: A Proposition for Territorial Development
Authors:   University of Agder, Department of Information Systems, Noruega, Sarate João Alberto Rubim , Macke Janaina ,   Universidade de Caxias do Sul, Caxias do Sul, RS, Brasil, Pecqueur Bernard ,   Université Grenoble Alpes, Grenoble, France
Published: November 2020

This study proposes an instrument to evaluate territorial social capital as a collective resource, found in the cooperation, trust and reciprocity relations. The evaluation of the territorial social capital was done in three neighboring areas in southern Brazil. These territories have common cultural aspects, although they have experienced different patterns of development. The results show that the territorial social capital can be analyzed according to four factors in this order: proximity, territorial anchorage, reciprocity and collective memory. The proximity and the territorial anchorage are the most powerful factors to explain social capital in these territories.
Tourist Ruralities of the Pampeano-Bonaerense Countryside [Argentina]
Authors:   Instituto de Ciencias Antropológicas, Ciudad Autónoma de Buenos Aires, Argentina, Winter Cecilia Pérez , Guastavino Marina ,   Instituto Nacional de Tecnología Agropecuaria (INTA), Ciudad Autónoma de Buenos Aires, Argentina
Published: November 2020

The goal of this article is to enquire into how state and non-state actors configured tourist versions of countryside. We propose to identify and examine, through three initiatives oriented by the Sub-secretary of Tourism of the Province of Buenos Aires, the National Institute of Agricultural Technology and private owners of agrarian productive establishments: who are participating in the construction of a tourist rurality; what elements [places, subjects, practices, versions of the past] are they selecting; what kind of representations are they creating and disseminating to guide tourism consumption of countryside. Our analysis leads us to consider that different actors build diverse versions of tourist pampas countryside, evocating practices and narratives about the agricultural past and the present.
Conflict of Resource Use Among Different Livelihood Group in Coastal Villages of South-Western Bengal Delta, Bangladesh
Authors: Swarnokar Sadhon Chandra , Ashik-Ur-Rahman Md , Mou Sadia Islam
Published: November 2020

People, ecosystems and resources are three crucial components for understanding resource use conflicts. This study examines resource use conflicts in two coastal villages of south-western Bangladesh, where access to resources are essential to rural livelihoods. Resource utilization conflicts can emerge when interests and needs of different users groups are incompatible or denied by each other. Considering these issues, this study has taken as an effort to explore the issues, reasons, stage, scale and impact of conflicts. Relevant data were collected through questionnaire survey, Focus Group Discussions (FGD) and Key Informant Interview (KII). The study found that rapid encroachment of crop land into shrimp farming, contrasting dynamic occupational practices, human made over use or overstrain of natural resources combined with environmental degradation and climate change, pose serious threat to human security. These rapid, and mostly unexpected changes provoke conﬂicts among the dominant resource user groups. Moreover, driver of conflicts and typological classification were addressed to make them comparable in the sense which one requires the most attention according to the predicted scale and urgency of impact. Conflict management strategies were discussed by four building blocks which might be a remarkable part of conflict prevention in the study area.
Effect of Air Pollution from Pedestrian Traffic in an Open Market: A Case Study of Bodija Market, Nigeria
Authors: Oladejo Oluyemisi J. , Odeyale Timothy O. , Adiamo Bukola R.
Published: November 2020

Market air quality is very important to the economic lives of the people which is rarely researched, however, market activities particularly pedestrian traffic releases particulates which is detrimental to the health of the users and stakeholders. Thermo scientific MIE pDR-1500 particulate was used to monitor the quality of air within the market for eight (8) weeks, air pollutant of concern is PM2.5. Ten (10) sample points were located in the market which covers ten (10) sample points for pedestrian traffic to represent the entire market environment spectrum. The analysis of PM2.5 measured daily during dry and wet season shows a clear seasonal variation of this particular pollutant as elevated concentration was measured during the dry season than the wet season. The assessment of PM2.5 concentration shows exceedances of the standards stated by WHO and NAAQS during the dry season which ranges from 47.9 μg/m3- 231.88 μg/m3 in the morning and 65.17 μg/m3- 1806.33 μg/m3 in the afternoon. From the findings, pedestrian traffic contributes immensely to air pollution in an open market, with this elevated concentration, prolonged exposure is highly detrimental to health. This study creates awareness to the pedestrians in an open market about air pollution and informs policy changes.
Intranasal Midazolam versus Intravenous Lorazepam in the Control of Acute Seizures in Children Aged 6 Months to 15 Years - An Open Label, Randomized Trial
Authors: Khadir Arif Thingal Abdul , Kumar Asok , Joji Prameela , Suseelan Kishore , Mohammed Jibina
Published: November 2020

BACKGROUND The rapidity with which a medication can be delivered to the systemic circulation and then into the brain always play a significant role in reducing the mortality and morbidity. We wanted to determine and compare the efficacy of intranasal midazolam with that of intravenous lorazepam in the control of acute onset seizures and side effects. METHODS This is an open labelled randomized control trial conducted in the Emergency Department of KIMS Hospital, which is a multi-specialty tertiary care centre in south Kerala, India, among children with acute seizure between 6 months and 15 years of age. They received intranasal midazolam or intravenous lorazepam. RESULTS 65.2 % (15) of the children in whom intranasal midazolam was given, seizures were controlled within 5 minutes from ER presentation, whereas in lorazepam group, only 34.8 % (8) children ceased to seizure within 5 minutes. P value was 0.039. CONCLUSIONS The overall time to cessation of seizure after arrival at hospital was faster with intranasal midazolam than intravenous lorazepam. No untoward side effects were noticed. KEYWORDS Acute Seizure in Children, Intranasal Midazolam, Lorazepam, Randomized Trial
A chasmosaurine ceratopsid premaxilla from the basal sandstone of the Hell Creek Formation, Montana
Authors: Scannella John
Published: November 2020

A well-preserved large chasmosaurine ceratopsid premaxilla (MOR 1122 7-22-00-1) collected from the basal sandstone of the Cretaceous Hell Creek Formation (HCF) represents one of the stratigraphically lowest ceratopsid occurrences in the formation. The specimen was discovered in 2000, during the excavation of a large Torosaurus latus skull (MOR 1122) which was later hypothesized to represent an advanced growth stage of the more commonly recovered HCF ceratopsid Triceratops. MOR 1122 7-22-00-1 compares favorably with the incomplete premaxillae of the MOR 1122 skull and reveals details of premaxilla morphology from this stratigraphic zone. It preserves large, closely spaced ventromedial foramina, a narrow triangular process, and a thin septal flange at the base of the narial strut. The nasal process is narrow, caudally inclined and has a forked dorsal surface which appears to represent an intermediate between the morphology expressed in the slightly stratigraphically lower ceratopsid Eotriceratops xerinsularis from the Horseshoe Canyon Formation of Alberta and specimens recovered higher in the HCF. MOR 1122 7-22-00-1 expresses a deep recess extending medial to the strut of the triangular process, a feature shared with other HCF ceratopsid specimens but not Eotriceratops or other earlier occurring triceratopsin taxa. The morphology of MOR 1122 7-22-00-1 is consistent with noted stratigraphic trends in HCF ceratopsids and highlights the increased complexity of the narial region in uppermost Cretaceous triceratopsins.
SPATIAL DISTRIBUTION, EVOLUTION AND STRUCTURE OF MAIZE AND SOYBEAN PRODUCTION SYSTEMS IN STATE OF PARANÁ
Authors: VOLSI BRUNO , CASTRO GUSTAVO HENRIQUE LEITE DE , COSTA GUSTAVO VAZ DA , SEVERINO MATHEUS FELIPE DE PADUA , TELLES TIAGO SANTOS
Published: November 2020

The Brazilian state of Paraná is one of the leading producers of maize. However, expansion of soybean cropping has caused a drop in maize production and could have impacted production systems. The aim of the study was to verify the evolution and identify the structure, spatial dynamics and transformation of maize and soybean production systems in the state of Paraná. Municipal Agricultural Production data from the Brazilian Institute of Geography and Statistics (IBGE) provided the basis for this study. The Location Quotient was analyzed to identify microregions specialized in the production of soybean and first and second crops of maize. Principal components and groups were analyzed in order to characterize the structure and dynamics of maize and soybean production systems in specialized microregions. The results show how maize and soybean production systems have been transformed; soybean is now cropped in areas previously occupied by first crop maize, and the area occupied by second crop maize has increased. This has led to the predominant use of the crop rotation system with first crop soybean followed by second crop maize.
YIELD COMPONENTS AND PRODUCTIVITY OF MAIZE AS A FUNCTION OF PREDECESSOR CROP
Authors: GONZÁLEZ MARÍA EMILIA BRUSQUETTI , DA SILVA JUNIOR IZAIAS RODRIGUES , DE SOUZA LUIZ CARLOS FERREIRA
Published: November 2020

Succession crops in no-tillage system can improve the soil attributes, thus favoring the growth and development of maize (Zea mays L.) and contributing to grain yield increment. The objective of this work was to verify the effect of succession crops on growth and development of maize planted in the summer and the influence on grain yield. For the study, a long-term experiment was implemented, beginning in September 2009, in dystroferric Red Latosol, on the Experimental Farm of the School of Agricultural Sciences of the Federal University of Grande Dourados (UFGD), located in the municipality of Dourados, Mato Grosso do Sul state. This article presents data collected from the 2017/2018 crop season. Randomized block design was used, with ten treatments and four replications. The treatments consisted of the crops preceding maize, such as millet (Pennisetum glaucum L.), oilseed rape (Brassica napus), oat (Avena sativa), safflower (Carthamus tinctorious), niger (Guizothia abyssinica), vetch (Vicia sativa), sunn hemp (Crotalaria juncea), and forage radish (Raphanus sativus). The predecessor crops positively influence dry matter mass of the aerial part of the plant, dry matter mass of 1000 grains, and productivity of the summer maize crop planted through the remains of straw (residues) of millet, oat, niger, sunn hemp, vetch and forage radish.
Análise da influência, nas propriedades físico – mecânicas, da adição de aditivos hidrofugantes em argamassa de revestimento
Authors: Antunes Elaine Guglielmi Pavei , Nascimento Karen Laisla Casagrande do
Published: November 2020

O sistema de argamassa tem a função de proteger e regularizar superfícies, além de servir como base para outros revestimentos. O sistema de revestimento argamassado pode apresentar algumas manifestações patológicas, dentre elas, a infiltração. A água é um dos principais geradores de patologias, de forma direta ou indireta, em quaisquer de seus estados físicos. A porosidade exerce um papel importante no transporte de água nas argamassas. Uma das maneiras de se impermeabilizar argamassas pode ser a inserção de aditivos de ação hidrofugante nas misturas. Os aditivos hidrofugantes têm a função de reduzir a taxa de penetração de água por absorção capilar, porém não previnem a penetração de água. O aditivo analisado trata-se de um composto químico da linha dos Silano e Siloxanos, entre outros aditivos. O presente trabalho visa analisar a inserção de distintas proporções de aditivos com função de impermeabilização em argamassa para revestimento. O traço unitário utilizado é de 1:6 (cimento e areia, em massa) e posteriormente traços com a adição de cal e dos aditivos. As propriedades físicas e mecânicas da argamassa foram analisadas através de ensaios de resistência à tração na flexão, resistência à compressão, módulo de elasticidade e absorção de água por capilaridade, além da análise microestrutural através da microscopia eletrônica de varredura. Os resultados dos ensaios demonstraram que as argamassas produzidas com o aditivo de um composto químico da linha dos Silano e Siloxanos no geral foram semelhantes as produzidas sem o aditivo, além disso, tratando-se do ensaio de absorção de água por capilaridade, teve um resultado similar aos traços sem a incorporação do aditivo.
Using eService-Learning to Practice Technical Writing Skills for Emerging Nonprofit Professionals
Authors: Bharath Del
Published: November 2020

Undergraduate students entering the nonprofit sector receive theoretical information on working in nonprofits but may need practical skills. Universities can assist in developing these practical skills through service-learning opportunities. Nonprofit courses and programs are increasingly being offered online and students may lack the opportunity to participate in traditional service-learning classes. Service-learning— linking service to course learning outcomes—as a pedagogy is transforming to meet the needs of these virtual classrooms. One key transformation is the rise of eServicelearning, a method that is mediated by technology and is delivered online. This paper discusses ways that eService-learning was effectively utilized in an online nonprofit course by students to practice technical writing skills. It provides an example of a project in which students developed practical skills and created a professional product for nonprofits. The paper also discusses challenges and successes with the project with recommendations for use by others.
Aglomeracja a park narodowy. Trudna relacja w warunkach afrykańskich – przypadek Nairobi i Parku Narodowego Nairobi
Authors: Adamus Justyna , Kępski Tomasz , Mika Mirosław
Published: November 2020

W artykule omówiono wybrane relacje między rozwojem aglomeracji Nairobi a funkcjonowaniem położonego w jej granicach Parku Narodowego Nairobi. Zwrócono szczególną uwagę na rozwój społeczno-ekonomiczny i przestrzenny Nairobi, który wywiera coraz silniejszą presję na ekosystem parku. Wśród głównych czynników antropopresji wymieniono przestrzenne rozlewanie się (sprawl) miasta oraz blokowanie korytarzy migracji ssaków na tereny poza parkiem. Potrzeby rozwojowe miasta stawiają pod znakiem zapytania przyszłość PN Nairobi, która w znacznym stopniu jest uzależniona od decyzji politycznych władz krajowych.
Innovation and Disruption: Exploring the Potential of Clinical Legal Education
Authors: Noone Mary Anne
Published: November 2020

It’s a great privilege to deliver this year’s Susan Campbell Oration. I, like many others, had the pleasure of working with Sue on a range of activities. In 2007, Sue conducted a review of the La Trobe Law School Clinical program which was instrumental in helping ensure the program remained an integral aspect of the La Trobe University law course. I hope what I have to say honours Sue’s memory and her contributions to legal education and clinical legal education in particular2.  My focus in this presentation is on how Australian clinical legal education responds to the various innovations and disruptions occurring in the legal arena. The scope and breadth of innovations is mindboggling. There are many predictions about what the future holds for the legal profession, from gloom and doom to utopia, and there is a growing body of literature discussing the implications for the legal profession and legal education. In reality, it is impossible to envisage what the legal world will look like in ten years let alone thirty and that poses a real challenge for those involved in legal education, including clinical legal education. How best to prepare today’s students for the unknown future?  Given that I have no expertise in digital technology and am certainly not a futurologist my comments relate to those areas about which I have some background: access to justice, social security and clinical legal education.  I briefly outline the variety and scope of innovations occurring in the legal world, discuss two related aspects namely access to justice and government decision making, using the example of Robodebt, and then examine the potential for clinical legal education in these disruptive times. I argue that clinical legal education is well placed to take a more central role in Australian law schools and the training of 21st century legal workers.
Family Law Clinic at UCC
Authors: Crowley Louise
Published: November 2020

Shulman extols the benefits of ‘empirical propositions’  emphasising the value of interrogating teaching approaches with a view to establishing evidence as to how students learn, and in turn crafting effective ways to teach. This article critically explores the design and assessment approaches adopted in the delivery of the Family Law Clinic Module at the Law School, University College Cork and interrogates the impact of these approaches on student learning. In carrying out this action research, the decision to utilise Universal Design for Learning as the underlying Scholarship of Teaching and Learning framework allows the pedagogical approach adopted to be deconstructed and critically examined. The capacity for student involvement in the teaching journey which is premised upon the ideology of learning and teaching as community property will be explored, both from a theoretical perspective and also from a socio-legal viewpoint. It will be shown that empowering the students to direct the module and assessment content serves to awaken their social awareness and their understanding of their role as pro-social contributors. Following an exploration of these aspects of SOTL thinking, the student learning experience will be explored through a number of qualitative research methods, namely individual student interviews post completion of the module, individual student reflective journals and the testimonial experience of external parties who utilise the Family Law Clinic research services. These approaches to understanding the student experience will serve to demonstrate the unique approach adopted in the Family Law Clinic that gives rise to a unique student learning environment and holistic student development.
Proceedings Book - Luso-Brazilian Meeting of Physiology, 2020
Authors: Monteiro Rodrigues et Al Luis
Published: November 2020

55th Annual Congress of SBFIS Proceedings’ Book Livro de Resumos do 55º Congresso Anual da SBFIS
Escala de avaliação da qualidade de cursos de licenciatura a distância
Authors: Garcia Marta Fernandes , Silva Dirceu da
Published: November 2020

O artigo apresenta o processo de construção e validação de uma escala para avaliação da percepção da qualidade de cursos de licenciatura na modalidade a distância. Para tanto, quatro procedimentos foram empregados: (1) revisão da literatura; (2) validação teórica ou de face; (3) validação semântica e (4) validação estatística, através da Modelagem de Equações Estruturais (MEE), com geração de um constructo de segunda ordem (Qualidade), usando-se o software SmartPLS 2.0. A escala do tipo Likert foi estruturada a partir da solicitação de atribuição de uma nota entre zero e dez e disponibilizada em uma plataforma online. A validação da Escala de Avaliação de Cursos de Licenciatura a Distância (EALDIS) contou com uma amostra de 1.060 estudantes de diferentes cursos de licenciatura a distância do Brasil. A versão final foi validada com 83 itens e 8 constructos. Os testes de confiabilidade dos dados, validade discriminante e preditiva, indicador de coeficientes de caminho e tamanho do efeito apresentaram indicadores de validação muito adequados. Desta forma, a escala apresentada se constitui num instrumento de pesquisa confiável, podendo contribuir para a avaliação de cursos de formação de professores em nível superior na modalidade a distância.
Orientaciones teóricas sobre procesos identitarios y trayectorias de maestros/as indígenas en la región chaqueña (Argentina)
Authors: Aliata Soledad
Published: November 2020

Este artículo es parte del trabajo de tesis doctoral en Antropología Social, centrada en documentar la diversidad y complejidad en las trayectorias socioeducativas de un grupo de maestros/as indígenas de la provincia del Chaco, Argentina. El presente escrito apunta a indagar en los principales ejes teóricos que atañen a nuestro problema de investigación vinculados con la figura de los/as maestros/as indígenas y los estudios sobre la noción de identidad. Creemos que la pertinencia teórica de esta investigación para los estudios centrados en la educación en contextos interculturales reside en poner en diálogo categorías que, si bien son frecuentes en las ciencias sociales, albergan significados y usos analíticos contradictorios y, en algunos casos, conflictivos. De este modo, la obra busca cuestionar las perspectivas esencialistas y cosificantes. A su vez, se espera reflexionar sobre la articulación entre la idea de trayectorias y procesos de identificación étnica que permiten evidenciar la heterogeneidad que existe en las interacciones sociales, y al mismo tiempo el carácter paradójico y espiralado que encarna la vida de los sujetos. Advertimos que la sistematización de los debates que presentaremos no agota la multiplicidad de enfoques sobre la temática. Se trata simplemente de un recorte teórico que efectuamos a los fines de mostrar los antecedentes que consideramos pertinentes para nuestra investigación.
Strategies for innervation of the neophallus
Authors: Hontscharuk Rayisa , Siotos Charalampos , Schechter Loren S.
Published: November 2020

A fundamental goal of phalloplasty includes the construction of a sensate neophallus. Both tactile and erogenous sensation are important for protective sensation (including retention of implantable penile prosthesis) as well as sexual satisfaction. This article will describe the sensory innervation of flaps commonly used for phalloplasty including the radial forearm flap, anterolateral thigh flap, and musculocutaneous latissimus dorsi flap. The sensory innervation of the perineum and external genitalia will be reviewed as a basis for selecting recipient nerves. Additionally, surgical techniques, such as neurorrhaphy, will be discussed. Finally, outcome data, although limited, will be assessed.
Liberalism against Etatism (on the Path towards Liberalism of the 21st Century)
Authors: Sheinis V.
Published: November 2020

In the 20th century, liberalism stood up in a fight against two authoritarian (totalitarian) regimes – the nazi one and the communist one. This lead to conclusion on the “end of history” – the end of the world competition in common forms. It took little time to make sure that sharp turns of historical processes are unpredictable, etatist (authoritarian, statist) regimes are diverse, and liberalism has to argue for its historically superior role in a dispute with them over and over again. In some cases, and in some ways, authoritarian regimes have proven to be more effective than liberal ones. This was discussed by qualified experts at international workshops held in Moscow in 2017–2018. Following these discussions, a book was published in 2019. The proceeding of the dispute is represented in this article. The liberal strategy has been searching for a synthesis of freedom and equality for more than a century. However, in practice, their organic convergence is problematic. It is difficult to balance the aims of liberals and socialists, and therefore, to define possibilities and limits of a dialogue between them. Social state is one of the main ideas that liberal parties bring to elections. But it is hard to compile with material and administrative resources concentration in state hands. Nations are a reality of the modern world. Building and developing civil nations within the borders of one state (and particularly of interstate formations) is the task that has no vivid and familiar solutions. The same as the problem of nation-state sovereignty (the apologetic attitude to which has become widespread) has no simple and unambiguous solution. The apparent success of illiberal (and in some countries – anti-liberal) methods of partial modernization is one of the most сruel surprises sprung on the liberal doctrine and policy by modern world processes. All this makes the promotion of liberal values in Europe and Russia very challenging.
Agile Transformation as an Adaptive System
Authors: Taesch Luc , Rochefolle Christophe , Touirat Miloud , Mortreux Denis , Boulinguez Stephan , Polombo Daniel , Manoukian Patrick
Published: November 2020

Most mature companies have started some kind of “transformation”, either digital, or agile transformations, to cope with changes in the environment, yet most fail, ending up delivering nothing or just one more reorganization. We postulate that considering the Organization as a self-aware Complex Adaptative System (CAS) is paramount, as the common conception (Industrial: mechanistic and predictive) results in bringing the systems in a frozen or defensive mode. Stimulating the system enables us to use its adaptative power to develop new capabilities, and all layers should be tackled simultaneously, to prevent the system from collapsing back into its original state. To ensure this, it is necessary to create a seed per level, and a mechanism to propagate the transformation, with a focus on development instead of growth, that is qualitative change rather than quantitative. A common vocabulary should also be provided, so conversations can occur at every level. Finally, changing mindsets is key, and both concepts and techniques should be provided as enablers to the adequate mindset level. We detail one such transformation that resulted in distributed leadership and more intrinsic motivation, providing both an account of the transformation itself and a model to read it.
Photobiomodulation of Human Fibroblasts and Keratinocytes with Blue Light: Implications in Wound Healing
Authors: Rossi Francesca , Magni Giada , Tatini Francesca , Banchelli Martina , Cherchi Federica , Rossi Michele , Coppi Elisabetta , Pugliese Anna Maria , Rossi degl'Innocenti Duccio , Alfieri Domenico , Pavone Francesco S. , Pini Roberto , Matteini Paolo
Published: November 2020

In recent years, photobiomodulation (PBM) has been recognized as a physical therapy in wound management. Despite several published research papers, the mechanism underlying photobiomodulation is still not completely understood. The investigation about application of blue light to improve wound healing is a relatively new research area. Tests in selected patients evidenced a stimulation of the healing process in superficial and chronic wounds treated with a blue LED light emitting at 420 nm; a study in animal model pointed out a faster healing process in superficial wound, with an important role of fibroblasts and myofibroblasts. Here we present a study aiming at evidencing the effects of blue light on the proliferation and metabolism in fibroblasts and keratinocytes. Different light doses were used to treat the cells, evidencing inhibitory and stimulatory effects. Electrophysiology was used to investigate the effects on membrane currents, while Raman spectroscopy revealed the mitochondrial Cytochrome C (Cyt C) oxidase dependence on blue light irradiation. In conclusion, we observed that the blue LED light can be used to modulate the activity of human fibroblasts, and the effects in wound healing are particularly evident when studying the fibroblasts and keratinocytes co-cultures.
Dual Aquaporin and Sigma1 Receptor (DAS) Modulators: New Tools for Counteracting Oxidative Stress
Authors: Pellavio Giorgia , Rossino Giacomo , Gastaldi Giulia , Rossi Daniela , Linciano Pasquale , Collina Simona , Laforenza Umberto
Published: November 2020

Specific aquaporins (AQP), called peroxyporins, play a relevant role in controlling H2O2 permeability and ensure reactive oxygen species wasting during oxidative stress. Another target involved in oxidative stress is the Sigma1 Receptor (S1R), since its activation is triggered by oxidative or endoplasmic reticulum stress. Herein we evaluated the effect of S1R modulators on AQP-dependent water permeability in the presence and in the absence of oxidative stress. Applying stopped-flow light scattering and fluorescent probe methods, water and hydrogen peroxide permeability in Hela cells have been studied. Results evidenced that S1R agonists can restore water permeability in heat-stressed cells and the co-administration with a S1R antagonist totally counteracted the ability to restore the water permeability. All compounds except one were able to counteract the oxidative stress of HeLa cells specifically knocked down for S1R. Taken together, our results support the hypothesis that the investigated compounds act as dual aquaporin and Sigma1 receptor (DAS) modulators. The finding that small molecules can modulate both AQP and S1R opens a new direction toward the identification of innovative drugs able to regulate cell survival during oxidative stress in pathologic conditions, like cancer and degenerative diseases.
Anxiety, Impaired Social and Aggressive Behaviour Correlates with Cognitive and Molecular Changes in Older SAMP8 Males
Authors: Vasilipoulou Foteini , Companys-Alemany Júlia , Canudas Anna-Maria , Palomera-Ávalos Verónica , Ortuño-Sahagún Daniel , Pallàs Mercè , Griñán-Ferré Christian
Published: November 2020

Alzheimer’s disease (AD) is characterized by cognitive impairment and different non-cognitive deficits called “Behavioural and psychological symptoms of dementia” (BPSD) related to neurotrophin alterations, which differ from those presented in normal aging. Mouse models, both transgenics and inbreed mice models of AD, are a useful tool in understanding the underlying mechanisms of the disease. The SAMP8 (senescence-accelerated mouse prone 8) mice line was generated from AKR/J strain by Professor Toshio Takeda at the University of Kyoto. This strain exhibited a particular early-onset and accelerated aging phenotype. The present study characterizes and provides information regarding the non-cognitive, cognitive and neurotrophin alterations and their correlation, demonstrating the AD-like symptoms presented in older males SAMP8. The cognitive impairment presented was accompanied by a reduction in sociability and an increase in aggressive as well as anxiety behaviours. Furthermore, changes in two of the most important neurotrophins, such as brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) were found. Thus, the present results reveal new insights in this useful inbred mouse model of neurodegeneration and AD, demonstrating the potential relationship between neurotrophin modifications, cognitive impairment and neuropsychiatric disorders (ND).
Study on Process Derivation and Characteristic Analysis for BLDC Design using Dual Rotor Method with High Torque Density
Authors: Lee Byeong-chul , Song Cheon-ho , Kim Do-hyun , Kim Ki-chan
Published: November 2020

In this paper, the design process of BLDC adopting the dual rotor method that can reduce the overall size of the motor while generating the same torque as the conventional Permanent Magnet BLDC is analyzed. A simple size is selected by obtaining the torque per rotor volume (TRV), and a method of matching the counter electromotive force by selecting the pole arc of the magnet through a magnetic equivalent circuit is analyzed. Since the efficiency is low because the 120-degree commutation method is selected, the middle stator is optimized through detailed design through the experimental design method. Afterwards, it has the advantage of being able to shift without stopping due to the characteristic of a dual rotor. For this, an analysis of the driving characteristics for each mode is performed.
Is Adiposity Associated with the Quality of Movement Patterns in the Mid-Adolescent Period?
Authors: Karuc Josip , Marković Goran , Mišigoj-Duraković Marjeta , Duncan Michael , Sorić Maroje
Published: November 2020

This study investigated the relationship between functional movement (FM) and adiposity in adolescents (16-17 years). This research is a part of the CRO-PALS study conducted in a random sample of adolescents (n=652, mean age±SD: 16.6±0.4). Body mass index (BMI), a sum of four skinfolds (S4S), waist and hip circumference were measured, and FM was assessed via Functional Movement Screen™ (FMSTM). Multilevel analysis were employed to determine the relationship between different predictors and total FMS score. After controlling for age, moderate-to-vigorous physical activity, and socioeconomic status, relationship between variables of adiposity and total FMS score was significant and negative among boys (BMI:β=-0.18, p<0.0001; S4S:β=-0.04, p<0.0001; waist circumference:β=-0.08, p<0.0001; hip circumference:β=-0.09, p<0.0001). However, among girls, in adjusted models, only S4S showed a significant and negative effect on total FMS score (β=-0.03, p<0.0001), while other coefficients failed to reach significance (BMI:β=-0.05, p=0.23; waist circumference:β=-0.04, p=0.06; hip circumference:β=-0.01, p=0.70). Results showed that the effect of adiposity on FM in adolescence is sex-specific, suggesting that boys with overweight and obesity could be more prone to develop dysfunctional movement patterns. Therefore, exercise interventions directed toward correcting dysfunctional patterns should be sex-specific, targeting more boys with overweight and obesity rather than adolescent girls with overweight and obesity.
Mapping the Melatonin Suppression, Star Light and Induced Photosynthesis Indices with the LANcube
Authors: Aubé Martin , Marseille Charles , Farkouh Ammar , Dufour Adam , Simoneau Alexandre , Zamorano Jaime , Roby Johanne , Tapia Carlos
Published: November 2020

Increased exposure to artificial light at night can affect human health including disruption of melatonin production and circadian rhythms and extend to increased risks of hormonal cancers and other serious diseases. In addition, multiple negative impacts on fauna and flora are well documented, and it is a matter of fact that artificial light at night is a nuisance for ground-based astronomy. These impacts are frequently linked to the colour of the light or more specifically to its spectral content. Artificial light at night is often mapped by using space borne sensors, but most of them are panchromatic and thus insensitive to the colour. In this paper, we suggest a method that allows high resolution mapping of the Artificial light at night by using ground-based measurements with the LANcube system. The device separates the light detected in four bands (Red, Green, Blue, and Clear) and provides this information for six faces of a cube. We found relationships between the LANcube’s colour ratios and 1- the Melatonin Suppression Index, 2- the StarLight Index and 3- the Induced Photosynthesis Index. We show how such relationships combined with data acquisition from a LANcube positioned on the top of a car can be used to produce spectral indices maps of a whole city in a few hours.
Mass Generation and Non-Euclidean Metric from Fractional Dynamics
Authors: Goldfain Ervin
Published: November 2020

Fractional-time Schrödinger equation (FTSE) describes the evolution of quantum processes endowed with memory effects. FTSE manifestly breaks all consistency requirements of quantum field theory (unitarity, locality and compliance with the clustering theorem), unless the order of fractional differentiation and integration ( ) falls close to the standard index . Working in the context of the minimal fractal manifold (where , ), we confirm here that FTSE approximates the attributes of gravitational metric and provides an unforeseen generation mechanism for massive fields.