bluuebunny/crossref_metadata_2025 huggingface dataset:
MEMBANGUN APLIKASI PENJUALAN DAN PENGENDALIAN PERSEDIAAN OBAT PADA APOTIK FINNA
Authors: Panggabean Hartoyo Indrajaya , Arifin Nur Alam , Pravitasari Norma
Published: January 2022

Apotik Finna memiliki permasalahan yaitu kesulitan dalam mengontrol stok obat yang ada di Apotik Finna, masih banyak karyawan Apotik Finna berkonsultasi dengan para karyawan dalam ketersediaan dan pendistribusian obat yang terdapat di Apotik Finna. Tujuan merancang suatu sistem informasi transaksi penjualan dan persediaan stok obat ini dengan tujuan untuk memudahkan admin dalam memproses pengolahan data yang ada saat ini. Perangkat aplikasi yang telah dibuat dengan bahasa pemrograman Java NetBeans 8.0.2 dan penyimpanan data pada database MySQL dapat memberikan kelancaran dalam proses menginput dan penyimpanan data-data serta laporan-laporan yang diberikan kepada pemilik apotik. Dengan menggunakan metode pengembangan sistem yaitu Waterfall dalam penelitian ini adalah dengan tahapan-tahapan seperti rekayasa sistem, analisis, desain, coding, testing, dan maintenance. Hasil dari penelitian ini menciptakan suatu sistem informasi pengolahan data dan transaksi penjualan pada Apotik Finna sehingga akan diperoleh informasi yang efektif dan efisien, yaitu membantu memperbaiki kesalahan dalam penulisan data, dan mempermudah dalam pembuatan laporan kepada pemilik apotik baik laporan data obat, data penjualan, data pembelian. Kata Kunci: Aplikasi, Penjualan, Persediaan, Obat, Desktop
PERANCANGAN APLIKASI PENGOLAHAN DATA PROYEK PERUSAHAAN KONTRAKTOR GUNASLAND BEKASI BERBASIS JAVA NETBEANS
Authors: Kurniawan Rizky , Destiawati Fitriana , Vandini Intan
Published: January 2022

Gunasland Bekasi adalah perusahaan didalam bidang kontraktor dalam pengembangan real estate yang beroperasi di Jakarta, Bekasi dan Jambi. Gunasland Bekasi juga memberikan penekanan kuat pada kehidupan rumah ramah lingkungan dengan terus meninjau tren dan teknologi baru dalam pengemabangan pembangunan hijau. Sebagai bagian dari apresiasi terhadap budaya Indonesia. Gunasland Bekasi sendiri belum memiliki aplikasi pengolahan data yang mana dalam pencarian datanya berupa file berkas dan proses laporan masih berupa dokumen. Tujuan penelitian ini dilakukan adalah untuk mengatasi sistem pengolahan data proyek yang ada, dimana sistem yang digunakan masih ada kekurangan dan belum optimal dan juga untuk merancang sebuah aplikasi yang dapat mempermudah segala sesuatu yang berhubungan dengan pengolahan data proyek perusahaan dan agar atasan dapat mengakses langsung data pada aplikasi, Seperti mudah hilang dan sulitnya dalam pencarian data. Metode penelitian yang digunakan adalah metode deskriptif Dapat dikatakan bahwa penelitian deskriptif merupakan penelitian yang berusaha mendeskripsikan suatu gejala, peristiwa yang terjadi pada saat sekarang atau masalah aktual. Berdasarkan metode tersebut pengumpulan data yang dilakukan memperoleh hasil data yang akurat. Hasil dari penelitian ini adalah sebuah aplikasi sistem informasi pengolahan data proyek yang sudah terkomputerisasi agar membuat pekerjaan menjadi lebih efektif lagi, terdata lebih baik dan tersimpan lebih aman.Kata Kunci: Perancangan, Pengolahan Data Proyek, Berbasis Java Netbeans
RANCANG BANGUN SISTEM APLIKASI PEMESANAN KAMAR PADA HOTEL MAHARANI
Authors: Alfarisi Salman
Published: January 2022

Belakangan ini sudah cukup banyak penyewaan kamar yang kita jumpai sering kali terlihat tidak teratur. Ini disebabkan oleh pendataan yang dilakukan belum terkomputerisasi yang artinya pencatatan kegiatan masih disimpan dalam beberapa berkas, yang mungkin akan menyebabkan ada kekurangan–kekurangan atau kesalahan-kesalahan yang sering dilakukan oleh karyawan bagian penyewaan kamar seperti kurangnya informasi mengenai kamar yang disewa apakah sudah selesai disewa atau belum, dan untuk mencari type kamar yang diinginkan diperlukan waktu yang relatif lama. Tujuan perancangan sistem pemesanan kamar ini adalah untuk mempermudah dalam mengelola data pemesanan kamar yang terdapat di Hotel Maharani agar pekerjaan menjadi efektif dan efesien. Selain itu sistem ini dapat membantu menyelesaikan permasalahan pemesanan kamar Hotel Maharani dapat terselesaikan dengan cepat, tepat, akurat guna mengefesiensikan waktu pekerjaan. Metode penelitian yang dipakai dalam penelitian ini adalah metode grounded research. Setelah dilakukan pengujian, Sistem pemesanan kamar ini dapat memenuhi kebutuhan akan suatu proses pemesanan kamar yang tepat guna dan cepat serta efektif dan efisien. Rancang bangun sistem pemesanan kamar ini menggunakan bahasa Java dengan IDE (Integrated Development Environment) dan untuk basis data menggunakan software mysql.Kata Kunci: sistem, pemesanan, hotel
PENGEMBANGAN E-MODUL KALFIS MATLAB GERAK VERTIKAL MENGGUNAKAN FLIP PDF CORPORATE EDITION
Authors: Sumarni Ria Asep , Dwitiyanti Nurfidah
Published: January 2022

Materi gerak vertikal yang disampaikan dalam kegiatan pembelajaran masih dalam bentuk Ppt dan video tutorial di Youtube. Agar dapat menarik kegiatan pembelajaran, maka diperlukan media pembelajaran yang lebih kreatif dan menarik. Sehingga pada penelitian ini, peneliti membuat media pembelajaran e-modul menggunakan flip pdf pada materi gerak vertikal yang berisi materi dan panduan membuat kalfis gerak vertikal menggunakan Matlab. Metode yang digunakan dalam penelitian ini adalah penelitian pengembangan atau Research and Development. Metode penelitian pengembangan adalah metode penelitian yang digunakan untuk menghasilkan suatu produk, serta menguji bagaimana keefektifan suatu produk. Dari hasil uji validasi ahli media dan ahli materi yang menyatakan bahwa e-modul kalfis matlab gerak vertikal menggunakan flip pdf Corporate Edition, layak digunakan sebagai media pembelajaran. Kemudian dilakukan uji coba kelompok kecil kepada mahasiswa untuk mengetahui kepraktisan e-modul, dan diperoleh hasil bahwa e-modul yang telah dibuat masuk dalam kriteria sangat praktis digunakan dalam pembelajaran membuat kalfis matlab gerak vertikal.Kata Kunci: e-modul, flip pdf, gerak vertikal
PERANCANGAN SISTEM PENJUALAN KREDIT RUMAH PADA PT. SURYA KREDIT PINTAR
Authors: Yunita Shania , Yulistyanti Dwi , Surajiyo Surajiyo
Published: January 2022

Pada umumnya masalah yang dihadapi oleh perusahaan yang belum terkomputerisasi dengan baik adalah belum memilikinya sistem komputer yang terintegerasi dan data olahan tersebut masih tersimpan dalam masing-masing komputer belum memiliki database server.Tujuan Penelitian adalah untuk menghasilkan Aplikasi Sistem Kredit Rumah yang bertujuan pada penerapan sistemnya adalah antara lain, dapat untuk mengidentifikasi persediaan rumah agar dapat memberikan data yang tepat dan akurat. Dan juga mengidentifikasi data pembeli agar dapat memberikan data yang akurat. Membangun aplikasi yang terdapat fitur untuk pendataan transaksi yang menghasilkan data laporan bulanan. Metode penelitian yang digunakan adalah metode research and development, yaitu suatu metode penelitian berdasarkan pada fakta dan menggunakan analisis perbandingan dengan tujuan mengadakan generasi empiris, menetapkan konsep, membuktikan teori, mengembangkan teori, mengumpulkan data dan analisa data dalam waktu yang bersamaan. Hasil penelitian ini menunjukkah bahwa salah satu cara yang dapat digunakan oleh perusahaan dalam mengelola pengkreditan rumah, metode ini dapat mengefisienkan biaya pemesanan dan biaya penjualan rumah sehingga laba perusahaan dapat dioptimalkan.Kata kunci : Penjualan, Kredit Rumah, Java
IMPLEMENTASI E-TICKETING KERETA API BERBASIS JAVA NETBEANS (STUDI KASUS : TANIA TRAVEL)
Authors: Nurhuda Mohammad , Pravitasari Norma
Published: January 2022

Pengelolaan data pemesanan pada Tania Travel masih dilakukan secara manual, dengan menggunakan lembaran kertas dan Microsoft Excel dan Microsoft Word. Pengelolaan data tersebut dirasakan banyak kekurangan yang terjadi seperti proses waktu yang lama dalam system pemesanan tiket. Pembangunan aplikasi data pemesanan membantu kecepatan dan kualitas dalam membuat laporan hasil data tiket dan sistem sistem data penumpang. Pada aplikasi ini hanya dapat diakses oleh user tertentu yaitu admin ticketing. Dalam penulisan ini selain memaparkan kajian teori yang digunakan sebagai dasar penyusunan juga akan dibahas mengenai perancangan aplikasi data pemesanan e-ticketing kereta api dengan menggunakan Netbeans dan MYSQL. Sehingga dapat memperbaiki segala kekurangan dan hambatan pada pengelolaan data pemesanan tiket dan dapat tercipta proses pelayanan yang cepat dan efisien.Tujuan Penelitian ini untuk membuat sebuah aplikasi yang dapat membantu permasalahan yang ada, yaitu dengan membangun sistem yang terkomputerisasi. Pada sistem ini menggunakan bahasa pemrograman java dengan software netbeans. Dalam analisis kebutuhan digunakan DFD (Data Flow Diagram) diantaranya adalah diagram konteks, diagram rinci dan diagram nol. Hasil yang dicapai adalah suatu sistem pelayanan tiket berbasis java netbeans yang sudah terkomputerisasi dan sudah menggunakan database.Kata Kunci: implementasi, e-ticketing, kereta api,dfd/dad,mysql
PERANCANGAN SISTEM APLIKASI REKAPITULASI PERJALANAN DINAS PADA DIREKTORAT JENDERAL MIGAS
Authors: Fadillah Septrianingsih Nur , Lestari Mei
Published: January 2022

Direktorat Jenderal Migas merupakan instansi pemerintahan di bawah Kementerian Energi dan Sumber Daya Mineral. Dalam sebuah instansi, rekapitulasi merupakan hal yang sangat dibutuhkan untuk membuat laporan akhir. Pada Direktorat Jenderal Migas salah satunya berupa rekapitulasi perjalanan dinas yang pencatatannya masih menggunakan Microsoft Excel. Penelitian ini bertujuan untuk merancang dan menerapkan suatu sistem aplikasi rekapitulasi perjalanan dinas pegawai agar dapat data tersusun dengan cepat, tepat dan akurat dalam proses rekapitulasinya. Metodologi penelitian yang digunakan adalah metode Research and Development dengan beberapa tahapan dimana untuk pengambilan data melalui pengamatan langsung, wawancara dengan pihak terkait, serta melakukan studi pustaka untuk mendapatkan informasi yang dibutuhkan. Hasil dari penelitian ini berupa perangkat aplikasi desktop yang dibuat dengan NetBeans IDE 8.2 bahasa pemrograman Java serta penyimpanan data menggunakan basis data MySQL. Pembangunan sistem ini dibantu dengan alat perancang sistem yaitu Diagram Alir Data (DAD) Konteks dan Diagram Nol. Sistem aplikasi yang dirancang ini dapat mempermudah staf pengadministrasi setiap unit dalam proses rekapitulasi perjalanan dinas pegawai pada Direktorat Jenderal Migas.Kata Kunci: Rekapitulasi, Perjalanan Dinas, Java, MySQL, Sistem Aplikasi.
A single nucleotide variant on chromosome 10 residing within PITRM1 distinguishes patients with basal-like human breast cancer.
Authors: Mamoor Shahan
Published: January 2022

Patients diagnosed with basal-like breast cancer face a more aggressive disease course and more dismal prognosis than patients diagnosed with luminal A and luminal B breast cancer molecular subtypes (1-4). We mined published microarray data (5, 6) to understand in an unbiased fashion the most distinguishing genetic and transcriptional features of tumors from patients with basal or basal-like subtype breast cancer. We identified a single nucleotide polymorphism, rs4242747, residing within PITRM1 as among the most significant genetic differences in the tumors of patients with basal-like breast cancer. In a separate cohort of patients with basal subtype breast cancer, we observed transcriptome-wide differential tumor expression of a PITRM1 transcript. Analysis of patient survival data revealed that PITRM1 primary tumor expression was correlated with recurrence-free survival in patients with luminal B breast cancer. Sequence variation in the PITRM1 gene may be important in understanding differences in genetic background that favor development of basal subtype human breast cancer.
Defacing biases manual and automated quality assessments of structural MRI with MRIQC
Authors: Provins Céline , Gómez Yasser Alemán- , Cleusix Martine , Jenni Raoul , Richiardi Jonas , Hagmann Patric , Esteban Oscar
Published: January 2022

Defacing (i.e. removing facial features) from structural imaging has become a necessary step before data sharing to ensure participants’ anonymity (Schwarz et al. 2021; Fig 1A). This process has proven to have some deleterious effects on the downstream research workflow (de Sitter et al. 2020). Here, we present an exploratory analysis prior to testing the hypothesis that both quality ratings by human experts and the image quality metrics (IQMs) that MRIQC (Esteban et al. 2017) extracts are affected by defacing. We found sufficient evidence on a small sample that there might be an effect. Therefore, we will pre-register and carry out a confirmatory analysis on a larger, unseen, sample.
Asuhan Keperawatan Jiwa Dengan Masalah Kecemasan Pada Penderita Hipertensi: Studi Kasus
Authors: SAMOSIR MARY LOWRENZA
Published: January 2022

Hipertensi merupakan salah satu penyakit kardiovaskuler yang paling umum dan paling banyak disandang masyarakat. Hipertensi sekarang jadi masalah utama kita semua, tidak hanya di Indonesia tapi di dunia, karena hipertensi merupakan salah satu pintu masuk atau faktor risiko penyakit seperti jantung, gagal ginjal, diabetes dan stroke
Analysis of Key Nutrition Indicators Based on National Family Health Survey, NFHS 4 (2015-16) and NFHS 5 (2019-2021)
Authors: Bhatia Neena , Rathi Komal , Arora Charu , Choedon Tashi , Rajurkar Pratik , Thakur Rinky , Shekhar Vedeika , Misra Archa , Patel Surendera Kumar , Sarwal Rakesh
Published: January 2022

This analysis on key nutrition indicators from successive rounds of the NFHS (4 and 5) is based on all-India and State/UT level factsheet released by Ministry of Health and Family Welfare (MoHFW). The analysis includes: 1. National level trends from NFHS-3 (2005-06), NFHS-4 (2015-16) and NFHS-5 (2019-21) data for 44 indicators including outcomes, service delivery and key determinants of nutrition. 2. State level trends of same indicators- number of states showing improvement / worsening (± 0.1 percent point change), /no change for these indicators, spatial maps based on change in prevalence for these indicators; and charting State performance with respect to achieving Sustainable Development Goals (SDG 2030) targets. This presentation will be useful for policy makers, State administrators, public health experts, research scholars and research institutes in the area of maternal and child health & Nutrition.
LITERATURE REVIEW: PENGARUH RELAKSASI GENGGAM JARI TERHADAP NYERI PADA IBU POST SECTIO CAESAREA
Authors: K Aninda Nuha
Published: January 2022

Latar Belakang : Persalinan dengan pembedahan sectio caesarea dapat mengakibatkan nyeri karena terjadinya perubahan kontinuitas jaringan. Oleh karena itu, perlu adanya cara pengontrol nyeri agar mempercepat masa nifas. Teknik relaksasi merupakan teknik nonfarmaklogis dengan merelaksasikan ketegangan otot yang mendukung rasa nyeri. Salah satu teknik relaksasi yaitu teknik relaksasi genggam jari. Tujuan : Mengetahui Pengaruh Relaksasi Genggam Jari Terhadap Nyeri Pada Ibu Post Sectio Caesarea. Metode : Jenis penelitian ini menggunakan metode literature review dengan cara menguraikan teori, temuan, dan bahan penelitian dari beberapa peneliti yang dijadikan sebagai landasan melakukan studi literature. Penelusuran artikel dilakukan dengan database Google Scholar yang dipublikasikan sejak 2016 sampai dengan 2020 yang diakses fulltext dalam format pdf. Hasil : Berdasarkan kelima artikel ilmiah yang disajikan oleh penulis, menunjukkan bahwa relaksasi genggam jari dapat membantu menurunkan nyeri dari skala sedang ke skala ringan pada ibu post sectio caesarea. Kesimpulan : Relaksasi genggam jari berpengaruh untuk mengurangi nyeri pada ibu post sectio caesarea.
Single nucleotide variants on chromosome 5 residing within MEF2C and MEF2C-AS1 distinguish patients with basal-like human breast cancer.
Authors: Mamoor Shahan
Published: January 2022

Patients diagnosed with basal-like (also known as basal) subtype breast cancer face a more aggressive disease course and more dismal prognosis than patients diagnosed with luminal A and luminal B breast cancer molecular subtypes (1-4). We mined published microarray data (5, 6) to understand in an unbiased fashion the most distinguishing genetic and transcriptional features of tumors from patients with basal or basal-like subtype breast cancer. We identified a single nucleotide polymorphism, rs616391, residing within MEF2C, as among the most significant genetic differences in the tumors of patients with basal-like breast cancer; further analysis revealed a separate SNP, rs214134, corresponding to MEF2C-AS1. In a separate cohort of patients with basal subtype breast cancer, we observed transcriptome-wide differential expression of a MEF2C transcript. Analysis of patient survival data revealed that MEF2C primary tumor expression was correlated with distant metastasis-free survival in patients with luminal B breast cancer. Sequence variation in the MEF2C gene may be important in understanding differences in genetic background that favor development of basal subtype human breast cancer.
Asuhan Keperawatan Jiwa Dengan Masalah Kecemasan Pada Penderita Kejang Demam: Studi Kasus
Authors: siregar lia permata sari
Published: January 2022

Kejang demam merupakan salah satu gangguan neurologik yang paling sering dijumpai pada masa anak-anak, terutama terjadi apabila demam disebabkan oleh infeksi yang mengenai jaringan ekstrakranial seperti tonsilitis, otitis media akut dan brokitis. Selain demam yang tinggi, kejang juga bisa terjadi akibat penyakit radang selaput otak, tumor, trauma atau benjolan dikepala serta gangguan elektrolit dalam tubuh
‘बर्सातमा बुद्धको मूर्ति सामु’ कवितामा शिल्प र् सौन्दर्य {Craft and beauty in the poem 'In front of Buddha statue in the rain'}
Authors: त्रिपाठी Tripathi गीता Geeta
Published: January 2022

प्रस्तुत अध्ययन कवि सुमन पोखरेलको ‘बर्सातमा बुद्धको मूर्ति सामु’ कवितामा अन्तर्निहित शिल्प सौन्दर्यको विश्लेषणमा केन्द्रितरहेको छ । कवितामा प्रयुक्त हुने भाषाको विशिष्टताको पाठपरक विश्लेषणका निम्ति यो कविता सोद्दश्य छनोट गरिएको हो । यसअध्ययनका निम्ति पुस्तकालयीय कार्यद्वारा अध्ययन सामग्रीहरू सङ्कलन गरिएको छ । कविताको विधागत विशिष्टता निर्धारण गर्ने मुख्य आधार यसमा प्रयुक्त भाषिक कला वा उक्तिगत विचित्रिता नै हो । यस अध्ययनमा उल्लिखित कवितामा चयन गरिएका पद र पदक्रमको विचलनयुक्त व्यवस्थितता, अर्थगत विपर्यास र समानान्तरता आदिमार्फत प्रस्तुत कविता शिल्पको विश्लेषणका निम्ति यसको आयामगत विस्तृति र भावगत परिग्रहणको समष्टिगत विश्लेषण गरी कवितामा प्रकट भएको बाह्य र आन्तरिक सौन्दर्यको मूल्याङ्कन गरिएको छ । यस मूल्याङ्कनबाट ‘बर्सातमा बुद्धको मूर्ति सामु’ कविताको आयाम र अर्थगत सौन्दर्य कवितात्मकताका पक्षमा विशिष्ट किसिमको रहेको निष्कर्ष प्राप्त भएको छ ।
Changing pattern of renal disease in children at pediatric nephrology clinic of a tertiary teaching hospital, Nepal: 10-year review
Authors: Kansakar Prerana , Anjum Md Feroz , Daha Sunil Kumar , Karn Anish
Published: January 2022

Introduction: Children present with different renal diseases with variations according to different geographic locations. This study aims to determine the trend of pediatric renal disease presenting.
Method: This retrospective study from pediatric nephrology clinic register during 2008 to May 2018 at Patan Hospital, Patan Academy of Health Sciences, Nepal to analyze the changing pattern of renal disease. The prevalence and characteristic of renal diseases were compared between the 1st and 2nd 5-y period, the age at presentation and gender was analyzed. Mean age at presentation was analyzed by independent t-test,  a p-value <0.05 was considered significant. The study was approved by the ethical committee.
Result: A total of 352 children visited the nephrology clinic, male:female ratio 1.42:1,  mean age 6.25±4.5 y, the majority in 0-5 y. Congenital anomalies of the kidney and urinary tracts (CAKUT) were 39%, mostly vesicoureteral reflux. Acute glomerulonephritis and the nephrotic syndrome were seen in 32.7% and 23.6%. Children <5 y of age presented with CAKUT while ≥5 y with acute glomerulonephritis. The mean age at presentation for CAKUT was 2.9±3 y and acquired diseases 8.46±3.91 y, p-value<0.05; and for glomerulonephritis 9.8±2.91 y and nephrotic syndrome 6.91±4.08 y, p-value<0.05.
Conclusion: There was a decrease in the number of children visiting the nephrology clinic. Children <5 y presented with CAKUT while ≥5 y had acquired conditions. Children with acute glomerulonephritis were of a higher age than children with nephrotic syndrome.
It Came in Waves: Doctoral Students Resilience During Covid-19
Authors: McWilliams MLe , Shields Sara Scott
Published: January 2022

This inquiry is focused on beginning to understand the graduate student experience in the midst of COVID, in hopes of identifying ways that faculty and students can support one another during the impending transition back to pre-pandemic life. This study enacts focus groups to explore the experiences of graduate students in an art education department at a large southeastern university. Through poetic assemblages, we use the arts to bring these experiences from the margins of institutional and pandemic narratives, into the center. This inquiry explores how sharing the stories of student vulnerability and resilience during the COVID pandemic might help transform post-pandemic teaching and learning environments into places that are responsive to student needs.
Pemilihan Pelanggan Potensial Dengan Melakukan Pemetaan Area Dengan Metode Algoritma K-NN dan K-Means Di Yamaha Nusantara Motor Purwokerto
Authors: Candrasari Diwahana Mutiara
Published: January 2022

This study proposes a clustering of potential customers at Yamaha Nusantra Motor Purwokerto based on consumer characteristics. Clustering is one of the processes of data mining that aims to partition existing objects into one or more clusters of objects based on their characteristics. The method used in this study is K-Nearest Neighbor as a determination of the feasibility of the data while K-Means is used as customer clustering. The value of the Davies Bouldin Index was examined using rapidminer while the purity validation was using Microsoft excel. The results show that the K-Means training data of the Davies Bouldin Index is 0.266 and the Purity validation is 1.3351. In the K-Means data testing the results show the Davies Bouldin Index value of 0.298 and the Purity validation of 0.6631.
Specifications Grading for Veterinary Medicine
Authors: Hofmeister Erik H. , Gibbons Philippa , Fogelberg Katherine , Conner Bobbi
Published: January 2022

Assigning grades in a traditional manner is often problematic: grades may or may not reflect actual student achievement, and students may base their self-worth on grades. Specifications (spec) grading claims to remedy these through a novel grading scheme. The scheme also purports to uphold high academic standards, reflect student learning, motivate students to focus on learning (rather than a grade), discourage cheating, reduce student stress, give students control over their grade, minimize conflict between students and faculty, save faculty time, make expectations clear, and facilitate higher-order learning. In spec grading, students must achieve 80% or higher to pass selected assignments, which include exams and quizzes, with the number and nature of assignments dictating the student’s final letter grade for the course. Students may resubmit assignments until they pass. Implementing spec grading requires creating assignments, determining assignment bundles, and communicating the new scheme to students to set clear expectations. The purpose of this tip is to describe how to develop a course using spec grading for didactic and clinical applications.
A Pan-Canadian Perspective on Education and Training Priorities for Physiotherapists. Part 2: Professional Interactions and Context of Practice
Authors: Kleiner Michelle J. , Walton David M.
Published: January 2022

Purpose: Canadian physiotherapists who participated in the Physio Moves Canada (PMC) project of 2017 identified the state of training programmes as a threat facing professional growth of the discipline. One purpose of the project was to identify priority areas for physiotherapist training programmes as identified by academics and clinicians across Canada. Method: The PMC project included a series of interviews and focus groups conducted across clinical sites in every Canadian province and in Yukon Territory. Data were interpreted using descriptive thematic analysis; identified sub-themes were returned to participants for reflection. Results: Overall, 116 physiotherapists and 1 physiotherapy assistant participated in 10 focus groups and 26 semi-structured interviews. Results are presented using the curriculum guidelines of the time for organization. Here we describe two themes: Physiotherapy Professional Interactions, further defined by interpersonal and interprofessional competencies, and Context of Practice further defined by advocacy, leadership, community awareness, and business competencies. Conclusions: Participants appear to express a desire for programmes to train reflexive and adaptable primary health care practitioners with strong foundational knowledge and clinical expertise, complemented by interpersonal and interprofessional skills to empower physiotherapists to effectively care and advocate for patients, to lead health care teams, and to share ideas to inspire change towards a future of physiotherapy practice.
Use of Galectin-3 in the Assessment of the Severity of Chronic Heart Failure Associated with Rheumatoid Arthritis. Results of the Analysis
Authors:   Irkutsk State Medical University of the Ministry of Health of the Russian Federation, Ankudinov A.S. ,   Irkutsk, Russian Federation, Kalyagin A.N.
Published: January 2022

Study Objective: To compare the galectin-3 levels in blood serum of patients with chronic heart failure (CHF) with moderately reduced left ventricular (LV) ejection fraction resulting from rheumatoid arthritis and without reumathoid arthritis; to assess possible associations with morphological and functional characteristics of myocardium. Study Design: Cross-sectional study. Materials and Methods. The study group included 134 patients with CHF with moderately reduced LV ejection fraction resulting from rheumatoid arthritis; 122 patients without rheumatoid arthritis were controls. All patients had class I–II CHF (according to The New York Heart Association classification). Rheumatoid arthritis was diagnosed on the basis of X-ray and serological examinations, which were used to measure rheumatoid factor, cyclic citrullinated peptide antibodies, С-reactive protein. Inflammation activity was assessed with the help of DAS28 index and a visual analogue scale of pain. Patients had X-ray stages I–III of rheumatoid arthritis (according to Steinbrocker). Methotrexate was a basic antiinflammatory drug for arthritis management. Patients who could not take methotrexate because of side effects and/or individual intolerability took Leflunomide 20 mg/day. Non-steroidal anti-inflammatory drugs were used as well (orally, parenterally, topically). Also, haematologic, biochemical and instrumental examinations were performed. Data were processed with the use of STATISTICA 10.0; the article shows only statistically significant results. The critical level of significance for statistical hypotheses testing was р < 0.05. Study Results. Statistically significant differences were found in galectin 3 groups: study group — 17.6 ± 9.8 ng/mL; control group — 14.6 ± 4.8 ng/mL (р = 0.0004). Statistically significant associations between galectin 3 and end-diastolic dimension (r = 0.02; p = 0.02), LV myocardial mass index (r = 0.05; p = 0.001), and atrial natriuretic peptide (r = 0.2; p = 0.001) were found. Conclusion. Patients with CHF demonstrated increased galectin 3 levels vs patients without arthritis and associations between galectin-3 with some morphofunctional myocardium factors. Keywords: chronic cardiac failure, rheumatoid arthritis, comorbidity, galectin-3.
Use of Nonsteroidal Anti-inflammatory Drugs in Cardiovascular Diseases: Problems and Solutions
Authors:   V.A. Almazov National Medical Research Center, Pakhomova I.G. ,   St. Petersburg, Russian Federation, Knorring G.Yu. ,   A.I. Yevdokimov Moscow State University of Medicine and Dentistry (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health; Moscow, Russian Federation
Published: January 2022

Objective of the Review: To analyse the contemporary idea of the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in cardiovascular comorbidities. Key Points. Adverse class-mediated side effects of NSAIDs complicate the use of these drugs in cardiovascular pathologies. Moderate Nimesulide selectivity is a cause of low risks of blood pressure destabilization, vascular catastrophes (acute myocardial infarction, stroke), other thrombotic complications recorded in clinical trials. Conclusion. These characteristics allow recommending Nimesulide in cardiovascular comorbidities, especially in situations where the use of other NSAIDs is limited due to side effects and contraindications. Keywords: nonsteroidal anti-inflammatory drugs, cyclooxygenase, comorbidity, cardiovascular diseases, Nimesulide, Nise.
Overlap of Irritable Bowel Syndrome and Uninvestigated Dyspepsia in Residents of Irkutsk
Authors:   Scientific and Research Institute of Medical Problems of the North of the Federal Research Centre “Krasnoyarsk Scientific Centre of the Siberian Branch of the Russian Academy of Science”, Tsukanov V.V. ,   Krasnoyarsk, Russian Federation, Vasyutin A.V. ,   Scientific and Research Institute of Medical Problems of the North of the Federal Research Centre “Krasnoyarsk Scientific Centre of the Siberian Branch of the Russian Academy of Science”; Krasnoyarsk, Russian Federation, Onuchina E.V. ,   Irkutsk State Medical Academy of Postgraduate Education – Branch of the Federal State Budgetary Educational Institution of Further Professional Education Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation; Irkutsk, Russian Federation, Petrunko I.L. ,   Irkutsk State Medical Academy of Postgraduate Education – Branch of the Federal State Budgetary Educational Institution of Further Professional Education Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation; Irkutsk, Russian Federation, Tonkikh Yu.L. ,   Scientific and Research Institute of Medical Problems of the North of the Federal Research Centre “Krasnoyarsk Scientific Centre of the Siberian Branch of the Russian Academy of Science”; Krasnoyarsk, Russian Federation
Published: January 2022

Study Objective: To study the overlap of irritable bowel syndrome (IBS) and uninvestigated dyspepsia in residents of Irkutsk. Study Design: Cross-sectional observational non-randomised study. Materials and Methods. We interviewed and examined 1,529 persons: 724 men and 805 women, the mean age of which was 51.0 years old. The questionnaire included questions to identify alarming symptoms. IBS and dyspepsia were diagnosed on the basis of Rome criteria IV. In our study, we used positive diagnosis of IBS and did not use instrumental examination; therefore, dyspepsia was treated as “uninvestigated dyspepsia”. Study Results. Prevalence of IBS was 12.3%, whereas uninvestigated dyspepsia was diagnosed in 19.1% of cases. Overlap of IBS and dyspepsia was recorded in 5.8% of subjects in the study group. Uninvestigated dyspepsia was diagnosed in 47.3% of patients with IBS and only in 13.6% of subjects without IBS (p < 0.001). The risk factors of overlap were the female sex (p < 0.001), age 50+ years old (p = 0.02), obesity (p = 0.03), and non-steroidal anti-inflammatory drugs and/or aspirin (p < 0.001). Conclusion. The overlap of IBS and uninvestigated dyspepsia was observed in Irkutsk. We assume that the results will be useful for improvements in the medical and preventive care to the population and for scientific developments. Keywords: syndrome of overlap, irritable bowel syndrome, dyspepsia, risk factors, Rome criteria IV.
Endoscopic Vacuum Therapy in Subtotal Esophagogastric Anastomosis Leaks
Authors:   Academician N.N. Burdenko Main Military Clinical Hospital, Ministry of Defence of Russia, Artemkin E.N. ,   Moscow, Russian Federation, Sokolov A.A. ,   Academician N.N. Burdenko Main Military Clinical Hospital, Ministry of Defence of Russia; Moscow, Russian Federation,   N.I. Pirogov Russian National Research Medical University (a Federal Government Autonomous Educational Institution of Higher Education), Russian Federation Ministry of Health; Moscow, Russian Federation, Tychinskaya K.S. ,   Academician N.N. Burdenko Main Military Clinical Hospital, Ministry of Defence of Russia; Moscow, Russian Federation, Kharitonova L.S. ,   Academician N.N. Burdenko Main Military Clinical Hospital, Ministry of Defence of Russia; Moscow, Russian Federation, Ryadinskaya I.A. ,   Academician N.N. Burdenko Main Military Clinical Hospital, Ministry of Defence of Russia; Moscow, Russian Federation, Sokolov D.V. ,   Academician N.N. Burdenko Main Military Clinical Hospital, Ministry of Defence of Russia; Moscow, Russian Federation
Published: January 2022

Objective of the Review: To demonstrate the efficiency of various methods of combined vacuum aspiration therapy (VAT) in a patient with an extensive defect of esophagogastric anastomosis after cancer-related cardiectomy. Key Points. Despite advances in surgery technique, advanced tools and suture materials, anastomosis suture defects in the upper part of the digestive tract are still a great concern. Prevalence of this complication is 0.5–20% of all surgery cases, with the mortality rate of 20–64%. Endoscopic vacuum therapy is a new method to manage anastomotic leaks; it boosts therapy efficiency and reduces mortality rates. This article describes a diagnostic and therapeutic algorithm for various therapy stages. Conclusion. This case of successful management of a patient with subtotal anastomosis leaks using VAT demonstrates possible uses of various methods to deliver a vacuum system to an anastomotic leak and their combinations. Keywords: vacuum aspiration therapy, esophagogastric anastomosis, anastomotic suture failure, splinting tube.
Clinical Observation of Pseudomembranous Colitis Complicated with Multiple Colon Perforations
Authors:   Municipal Clinical Hospital No. 52 of the Moscow Department of Health, Vtorenko V.I. ,   Moscow, Russian Federation, Rozumnyy A.P. ,   A.I. Yevdokimov Moscow State University of Medicine and Dentistry (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health; Moscow, Russian Federation, Loktev V.V. ,   Municipal Clinical Hospital No. 52 of the Moscow Department of Health; Moscow, Russian Federation, Mikhailov V.G. ,   Municipal Clinical Hospital No. 52 of the Moscow Department of Health; Moscow, Russian Federation,   A.I. Yevdokimov Moscow State University of Medicine and Dentistry (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health; Moscow, Russian Federation, Mudarisov R.R. ,   Municipal Clinical Hospital No. 52 of the Moscow Department of Health; Moscow, Russian Federation, Varyasin V.V. ,   Municipal Clinical Hospital No. 52 of the Moscow Department of Health; Moscow, Russian Federation
Published: January 2022

Objective: To present a clinical observation of a patient with pseudomembranous colitis (PMC) complicated with multiple colon perforations, and of post-surgery recovery. Key Points. Severe PMC can cause complications, such as toxic dilatation and perforation on colon, requiring emergency surgery. Clinical observation demonstrates the advisability of extended surgery for a patient with PMC complicated with perforations. Conclusion. PMC is a dangerous disease; a severe disease can cause colon perforation and require emergency surgery. Near-total colon excision in perforation in patients with PMC is justified and a most advisable type of surgery. Keywords: pseudomembranous colitis, multiple perforations, general peritonitis.
Bryozoa from the Posyeta Bay, Sea of Japan
Authors: Gontar V.I.
Published: January 2022

A list of 17 species collected in 1982 is given. Six species (two of them identified to the generic level only) are new to the fauna of the Posyeta Bay.
Test génétique présymptomatique chez les mineurs à risque pour la maladie de von Hippel-Lindau et surveillance des porteurs de mutation — Aspects psychologiques et éthiques
Authors: Lahlou-Laforêt K. , Vibert R. , Richard S. , Gimenez-Roqueplo A.-P.
Published: January 2022

Les tests génétiques présymptomatiques chez les sujets mineurs soulèvent un questionnement éthique. Dans cet article, nous décrivons le protocole de test génétique présymptomatique de la consultation multidisciplinaire des cancers rares de l’hôpital européen Georges-Pompidou. Nous rapportons les résultats d’une étude rétrospective réalisée sur une population de 20 sujets mineurs à risque pour la maladie de von Hippel-Lindau, testés à notre consultation et adressés au centre de référence de la maladie (centre PREDIR). Les objectifs étaient d’évaluer la compliance au suivi et le bénéfice effectif de la surveillance. Les résultats montrent une compliance totale sur la durée du suivi et confirment le bénéfice médical du test présymptomatique, qui est associé au dépistage effectif des tumeurs.
Predictive factors for recovery from adult growth hormone deficiency after transsphenoidal surgery for nonfunctioning pituitary adenoma
Authors: Kinoshita Yasuyuki , Taguchi Akira , Tominaga Atsushi , Arita Kazunori , Yamasaki Fumiyuki
Published: January 2022

OBJECTIVE

Recovery from adult growth hormone deficiency (AGHD) after transsphenoidal surgery (TSS) has not been well discussed because of the lack of examinations including pituitary provocation tests (PPTs) before and after the procedure. This study aimed to evaluate the growth hormone (GH) axis function of patients with nonfunctioning pituitary adenoma (NFPA) via pre- and postoperative PPTs. Moreover, the predictive factors for recovery from AGHD after TSS were validated to facilitate surgery for AGHD in patients with NFPA.

METHODS

In total, 276 patients (median age 60.0 years) who underwent TSS for NFPA were included in this study. PPTs were performed before and 3 months after TSS. Then, the relationships between recovery from AGHD after TSS and clinical, surgical, and hormonal factors, including peak GH level based on PPTs, were evaluated statistically.

RESULTS

In this study, 114 patients were diagnosed with preoperative AGHD. Approximately 25.4% recovered from AGHD after TSS. In contrast, among the 162 patients without preoperative AGHD, 13 (8.0%) had newly developed postoperative AGHD. The predictive factors for recovery from AGHD were younger age, female sex, initial TSS, and high peak GH level based on preoperative PPT. According to the receiver operating characteristic curve analysis, patients who were aged ≤ 62.2 years and had a peak GH level of ≥ 0.74 μg/L based on preoperative PPT were likely to recover from AGHD (sensitivity: 82.8%, specificity: 72.9%, and area under the curve: 0.8229).

CONCLUSIONS

AGHD caused by NFPA can improve after initial TSS among young patients with certain peak GH levels assessed by preoperative PPT. Whether TSS for NFPA can promote recovery from AGHD is worth considering in some patients.
Cumulative strain-based metrics for predicting subconcussive head impact exposure–related imaging changes in a cohort of American youth football players
Authors: Miller Logan E. , Urban Jillian E. , Espeland Mark A. , Walkup Michael P. , Holcomb James M. , Davenport Elizabeth M. , Powers Alexander K. , Whitlow Christopher T. , Maldjian Joseph A. , Stitzel Joel D.
Published: January 2022

OBJECTIVE

Youth football athletes are exposed to repetitive subconcussive head impacts during normal participation in the sport, and there is increasing concern about the long-term effects of these impacts. The objective of the current study was to determine if strain-based cumulative exposure measures are superior to kinematic-based exposure measures for predicting imaging changes in the brain.

METHODS

This prospective, longitudinal cohort study was conducted from 2012 to 2017 and assessed youth, male football athletes. Kinematic data were collected at all practices and games from enrolled athletes participating in local youth football organizations in Winston-Salem, North Carolina, and were used to calculate multiple risk-weighted cumulative exposure (RWE) kinematic metrics and 36 strain-based exposure metrics. Pre- and postseason imaging was performed at Wake Forest School of Medicine, and diffusion tensor imaging (DTI) measures, including fractional anisotropy (FA), and its components (CL, CP, and CS), and mean diffusivity (MD), were investigated. Included participants were youth football players ranging in age from 9 to 13 years. Exclusion criteria included any history of previous neurological illness, psychiatric illness, brain tumor, concussion within the past 6 months, and/or contraindication to MRI.

RESULTS

A total of 95 male athletes (mean age 11.9 years [SD 1.0 years]) participated between 2012 and 2017, with some participating for multiple seasons, resulting in 116 unique athlete-seasons. Regression analysis revealed statistically significant linear relationships between the FA, linear coefficient (CL), and spherical coefficient (CS) and all strain exposure measures, and well as the planar coefficient (CP) and 8 strain measures. For the kinematic exposure measures, there were statistically significant relationships between FA and RWE linear (RWEL) and RWE combined probability (RWECP) as well as CS and RWEL. According to area under the receiver operating characteristic (ROC) curve (AUC) analysis, the best-performing metrics were all strain measures, and included metrics based on tensile, compressive, and shear strain.

CONCLUSIONS

Using ROC curves and AUC analysis, all exposure metrics were ranked in order of performance, and the results demonstrated that all the strain-based metrics performed better than any of the kinematic metrics, indicating that strain-based metrics are better discriminators of imaging changes than kinematic-based measures. Studies relating the biomechanics of head impacts with brain imaging and cognitive function may allow equipment designers, care providers, and organizations to prevent, identify, and treat injuries in order to make football a safer activity.
"The railroad" vehicle for the reconstruction of the historical memory of Girardot from the oral accounts of railwaymen. Case study: life stories of three railwaymen
Authors: Claros Hoyos Valentina , Ariza Rodríguez Cindy Mariana , Aranda Sepúlveda Nicolás
Published: January 2022

The economic, political, social and technological development of the territories reflected in the world today are narrated through stories that represent their territorial cultural identity, therefore, capturing these events as a starting point for the reconstruction of a Memory is essential, especially if they are told by their protagonists. Reason for which this qualitative biographical research arises. For the study, semi-structured interviews were carried out with three railway pensioners, also, a theoretical triangulation was applied under the concepts of historical memory, cultural heritage and oral stories, and finally, an opinion poll was carried out to understand the importance of the railway and its reconstruction from the individual narratives of the railwaymen. The compilation of the oral accounts of the three railway pensioners will obtain the recognition of the narratives as fundamental vehicles for the reconstruction of the memory of Girardot, just as, such a historical journey made possible the analysis of the close relationship of its inhabitants with this, what that achieved an approach to the realities and practices of individuals in the historical journey for the reconstruction of the memory of a city.
Reconfigurations in couple construction: analysis of the existential continuum in women
Authors: Mayorga González José Miguel , Camargo Barrero José Antonio , Caita Alvarado María Alejandra
Published: January 2022

The dialogic exchange from digital media marks one of the main spaces for couple building. Thus, this article seeks to understand the experiences of women in the process of couple building from the existential continuum and discontinuum, given the absence of information on women's experiences in couple building today. The development of the same is framed in the qualitative-phenomenological methodology, describing the subjective and intersubjective accounts of women between 20 and 32 years old, responding to the question "How are couple relationships constructed nowadays from an existential point of view? As a result, two questions are answered: What would be the present causes that maintain the way of existing of women in the process of building a couple, and what would be, from the results found, the way of existing that allows acting in a reflexive and responsible way?
Influence of critical reading on the quality of meaningful learning in the area of language and literature
Authors: Mosquera Mora Adriana Del Rocío
Published: January 2022

This project was conducted at the Benemérita Sociedad Filantrópica Educational Unit in the seventh grade of basic education, school year 2015 - 2016. The objective of the research was to examine the influence of critical reading on the quality of meaningful learning through a bibliographic study and statistical field analysis. The research used surveys that were applied to teachers, administrators and students of the school, the data analysis detailed the lack of interest shown by students towards reading, making the comprehension of reading complex. From the students' perspective, the readings done in class become theoretical and tedious, which leads them to be easily distracted in the teaching-learning process. This has created barriers at the moment of encouraging active interaction among class members. On the other hand, it was found that some teachers did not apply dynamic activities that relate educational content with different experiences, minimizing the development of meaningful learning in students. This series of aspects led to the elaboration of a proposal that allows teachers to apply innovative activities that can be adapted to the different educational content present in the area of Language and Literature.
Incidência de uma dieta equilibrada no desempenho académico dos estudantes
Authors: Fany Castro Jacqueline
Published: January 2022

Actualmente o desempenho académico dos estudantes em todo o mundo é muito importante porque o estudante constrói os seus próprios conhecimentos, o mesmo que está relacionado com vários factores, incluindo o facto de estar bem nutrido. Este projecto educativo irá analisar o impacto de uma dieta equilibrada no desempenho académico dos alunos do ensino básico na escola pública Manuel Benjamín Carrión, na cidade de Guayaquil, uma vez que ficou demonstrado que os pais não estão preocupados em dar- lhes uma dieta equilibrada e desconhecem o conteúdo proteico dos alimentos, causando problemas na saúde dos seus filhos e no desenvolvimento cognitivo. As crianças que vão à escola sem pequeno-almoço não estão motivadas, têm notas baixas nas suas disciplinas, e adormecem nas aulas. Segundo a psicóloga clínica, Carolina Peña, há também o problema do baixo desempenho académico devido a factores emocionais, pedagógicos e psicológicos.