bluuebunny/crossref_metadata_2025 huggingface dataset:
DETERMINANT FACTORS OF PATIENT SATISFACTION AND TRUST IN PHARMACY STAFF AMONG PERSONS WITH NON-COMMUNICABLE DISEASES: PATIENT CENTERED CARE APPROACH
Authors: Nurjanah Siti Rahayu , Pribadi Prasojo , Dianita Puspita Septie
Published: November 2022

Patient satisfaction and trust are the main focus in the context of health care. Patient satisfaction is influenced by medication service factors, handling patient complaints and listening to patient needs. Important to develop and test a patient-centered care model as a tool to monitor, measure, analyze, and increase patient satisfaction and trust among people with non-communicable diseases in Public Health Center service setting. This study attempts to ascertain the effect of care on patient satisfaction and trust in pharmacy staff at the Magelang City Public Health Center. Cross-sectional quantitative research is used in this field. 212 people participated as the sample. Non-probability sampling using a purposive sample strategy was used as the sampling technique in this investigation. Structural Equation Modeling-Partial Least Square (SEM-PLS) is used for hypothesis testing. According to the study's findings, patient satisfaction is positively impacted by pharmacy staffs’ participative behavior and interpersonal communication (p< 0.05). Interpersonal communication and pharmacy staff participation do not affect the trust in pharmacy staff (p> 0.05). Patient satisfaction plays a moderating role in the association between pharmacy staff participation and trust in pharmacy staff (p< 0.05). Likewise, the association between interpersonal communication and trust in pharmacy staff is mediated by patient satisfaction (p< 0.05).
SIMULTANEOUS CONTENT ANALYSIS OF RIFAMPICIN, ISONIAZID, AND PYRAZINAMIDE IN TABLET DOSAGE FORM BY SPECTROPHOTOMETRY ULTRAVIOLET WITH DWM AND RSM
Authors: Andry Muhammad , Luthvia Luthvia
Published: November 2022

Treatment of active tuberculosis requires the use of combinations of drugs. One of the common combination of drugs to serve as anti-tubercular medication is rifampin, isoniazid and pyrazinamide. However, a research conducted by the Food Drug Administration (FDA) concluded that the combination of anti-tubercular medication may pose some patients to the risk of sub-optimal drug exposure, which may lead to less optimal treatment. This study aimed to determine the drug level of combination of anti-tubercular medication, namely rifampin, isomiazid, and pyrazinamide and to develop a spectrophotometric method using the dual wavelength method (DWM) and ratio substaction method (RSM) in tablet preparations on the market without separation. During the preparation, methanol was used as the solvent, followed by dilution, determination of calibration curve, determination of wavelength (λ), measurement, data analysis and validity test with several parameters ranging from linearity, accuracy, precision, LOD, and LOQ. The research revealed that the drug levels of rifampin, isoniazid, and pyrazinamide from the ultraviolet spectrophotometric method using sequential DWM were 100.3±1.8785; 99.98±2.5943; 100.03±2.076 and the results of the ultraviolet spectrophotometric method using RSM sequentially were 99.73±0.5437; 99.84±1.7598; 99.91±1.4762. Both methods succeeded in determining the drug level of the combination of rifampin, isoniazid, and pyrazinamide in tablet preparations without separation and the results of the validation parameters met the requirements.
État de connaissance des médecins urgentistes sur la prise en charge des intoxications au monoxyde de carbone en région Auvergne-Rhône-Alpes
Authors: Martinez(†) M. , Durand M. , Jainsky L. , Serre P. , Vallot C. , Jacquet L. , Freyssenge J.
Published: November 2022

Objectif : L’intoxication au monoxyde de carbone (ICO) est un diagnostic souvent difficile en urgence. Son incidence restant faible, les médecins urgentistes (MU) y sont rarement confrontés mais la pertinence de leur prise en charge est essentielle pour limiter la morbi-mortalité. L’objectif principal de cette étude était d’évaluer le niveau de connaissance des MU sur la prise en charge des ICO dans une région française de 8,1 millions d’habitants. L’objectif secondaire était d’individualiser les facteurs associés à une bonne connaissance de la prise en charge en urgence de cette pathologie.

Matériel et méthodes : Étude descriptive multicentrique et déclarative, réalisée auprès de MU travaillant au sein de cette région à l’aide d’un questionnaire en ligne.

Résultat : 246 MU ont répondu à l’enquête, représentant 82 % des structures de médecine d’urgence de la région. Parmi eux, 27 % estimaient prendre en charge moins de deux ICO par an. Le protocole territorial était connu par 59 % des répondeurs. La médiane de réponses justes au questionnaire de connaissance était de 43 [40-47] sur 60. Un taux de réponses justes plus faible (< 70 %) était retrouvé sur les questions traitant du diagnostic (65 %) et des indications et contre-indications de l’oxygénothérapie hyperbare (61 %). Les facteurs associés à un meilleur taux de réponses justes étaient : la connaissance du protocole territorial (63 vs 46 %,p= 0,035), une ancienneté d’exercice ≥ 5 ans (60 vs 40 %,p= 0,014), une formation complémentaire à la médecine hyperbare (85 vs 53 %,p= 0,018), un nombre estimé de prise en charge d’ICO ≥ 2 (60 vs 43 %,p= 0,022) et une auto-évaluation de ses connaissances > 7/10 (68 vs 50 %,p= 0,007).

Conclusion : Cette étude a montré un niveau de connaissance perfectible des MU sur cette pathologie en rapport avec un faible nombre de prise en charge annuel. La création d’un consensus national est à encourager pour améliorer les pratiques.
Smart Halal Destination Ecosystem Model: Measurement and Performance in Tourism Village
Authors: Sutono Anang , Rahtomo Wisnu , Sumaryadi  , Puksi Faisal F. , Permana Odang , Tahir Shaharuddin , Li Liu
Published: November 2022

Purposes - This study examines the application of the Smart Halal Destination (SHD) ecosystem model in Pagerharjo tourism village, Yogyakarta. This model is used to measure the effectiveness, efficiency, and integration through technology systems to discover the performance of destination Muslim-friendly competitiveness. Methods - This study uses a quantitative approach to assess a destination as a Muslim-friendly tourism destination. This research was conducted in three stages: Desk Research, Focus Group Discussion, Survey, and Interview. Findings – Based on the results of the assessment of each pillar, element, and attribute, Pagerharjo tourism village has advantages in the product pillar, especially on the attribute of “ambiance” and pillar of policy, especially on the attribute “has a pre-determined superior area”. Meanwhile, the attribute that still needs to be improved is the availability of slaughterhouses/poultry. Overall, Pagerharjo tourism village is considered sufficient to meet the criteria in developing a Muslim-friendly tourism village.
Analysing Show Cause Notices based on Applied Genre Analysis: a Multi- perspective Model
Authors: Zafar Mehreen , Raza Danyal , Latif Afraz
Published: November 2022

The current research papers targets to investigate the genre of Show Cause notices (SCNs) based on theoretical approaches of genre analysis (Bhatia, 1999) and applied genre analysis (Bhatia, 2002). The reason to carry the said study is to identify the correlation among the textual, generic and social perspectives of Show cause notices. The corpus of ninety show cause notices was gathered and analyzed by applying applied genre analysis: a multi-perspective model of Bhatia (2002). The theoretical concerns (1999) directed towards the language use in four categories; purpose, products, process and players which are affirmed through the analytical analysis. The findings through qualitative and quantitative paradigms of research represented that purpose of the SCNs and lexico-grammatical features are the mainstreams to suggest the structure patterning in the text to shape such genre as highly formal, objective and professional. The social perspective reflected the participants in no personal terms, clear separate power zones and the addresser's cognitive understanding of communicative event and purpose.
Strategies Used by the Teachers to Reduce Students' Disruptive Behavior in Classroom
Authors: Zuhra Um e Baneen , Parveen Qaisara , Yousaf Imran
Published: November 2022

Disruptive behaviour of students in a classroom is a serious hurdle for effective learning and teaching process. This quantitative study was conducted to explore the strategies used by the teachers to reduce disruption in the classroom and data was collected through a survey. The population of this study was all female and male teachers teaching in public sector colleges of District Chakwal. To represent the entire population, through a convenient sampling technique, 13 public sector colleges were selected from District Chakwal and 176 teachers were randomly selected for data collection purposes. A self-developed research questionnaire was used for data collection after validation and reliability assessment. The results showed that most of the teachers practice proactive, reactive, recognition and reward strategies. In the light of findings, it is recommended that teacher training institutions should introduce modern behaviour management strategies in the curriculum of teacher training programs so that, teachers can perform their teaching activities in an excellent manner.
Conceptual Study regarding the Effect of Cognitive Anxiety and Self-confidence on the Performance of Basketball and Volleyball Players
Authors: Kousar Rehana , Qureshi Bilal Ahmad , Yousaf Manzar Shabab
Published: November 2022

The goal of the current study was to find out how cognitive anxiety and self-confidence affected the performance of basketball and volleyball players. Female intercollegiate volleyball and basketball players made up the study's sample. For this investigation, a stratified sampling strategy was employed. Each segment's sample of 150,150 females age was limited to 16 to 21 (Mean=18.5 and Stander Deviation=1.87). Female basketball and volleyball teams from Sargodha District College that took part in the district of Sargodha in Sargodha District from 2015 to 2016 were the only ones included in the innovative study. To investigate the effect of an independent variable on a dependent variable, adopted questionnaires were utilized. The data was tabulated and then subjected to regression and inferential statistics. Results showed that anxiety has a significant negative impact on the performance of basketball and volleyball players. Additionally, it was discovered that there was no association between dependent and independent variables. It was suggested that the coaches should receive extensive facilitation as a coping mechanism to boost their self-assurance and prevent worry, which would ultimately improve their performance. Additionally, it was suggested that coaches and trainers may provide a peaceful environment to athletes and basketball and volleyball players so that they keep away from cognitive anxiety and enhance their self-confidence.
Investigating the Tenets of Post-structuralism in George Orwell's Animal Farm
Authors: Khan Nazia Hassan , Bashir Marriam , Khan Raj Wali
Published: November 2022

In literary theory, the term Post-structuralism is a prominent concept which is built upon structuralism and at the same time it negates the ideas associated with that. Though post-structuralists all present different critiques of structuralism, common themes among them include the rejection of the self-sufficiency of structuralism, as well as an interrogation of the binary oppositions that constitute its structures. Accordingly, post-structuralism discards the idea of interpreting media (or the world) within pre-established, socially constructed structures. The purpose of this research was to revisit Post-Structuralism by selecting George Orwell's Animal Farm as a target text for this research. Post-Structuralists like Derrida (1966),Foucault (1994), and Barthes (1975) argue that no ultimate truth can be found with the help of binary opposition. Power and knowledge change the truth and pre-existing realities into a new phenomena. This research endorses the ideas of poststructuralists and Animal Farm offers allegorical representation which indicates a multiplicity of truth.
Constitutionality of Law-making Process in Pakistan: A Critical Appreciation
Authors: Ali Mumtaz , Rehman Hafiz Aziz Ur
Published: November 2022

This is the age of information and awareness. Democracy cannot flourish without the involvement of the governed in all aspects of political life. Like good citizens, a question comes to mind to ask whether the Parliament of Pakistan is without any limitations in the area of legislation or whether there are constitutional limitations in this regard. Because it is the motto of a good citizen to obey punctually but to censure freely. With qualitative research methodology, this research paper examined both primary and secondary sources, which included a critical analysis of constitutional provisions, other legislative instruments, published research papers, and judicial precedents, in order to theorize the concept of separation of powers in Pakistan and judicial check on the legislature so as to counter apprehension of exploitation of legislative authority.
Factors Affecting the Profitability of Banks in Pakistan
Authors: Chughtai Usman Anwar , Abid Muhammad , Rasheed Adnan
Published: November 2022

This study examines the relationship between bank-specific and external factors on the Banks’ profitability in Pakistan from the time span of 2006 to 2012. In this study, 11 variables have been selected after reviewing relevant past literature. Variables include 1 dependent variable (i.e. Profitability), and 10 independent variables, out of which 7are internal/bank-specific and 3 are external variables. Internal factors include Liquidity, deposits, bank Size, expense management, credit risk, capital, and loans whereas external factors include economic growth (GDP), Interest rate and Inflation.The experimental consequences have shown that internal/Bank specific and external factors have a strong impact on the profitability of banks in Pakistan. In model 1 Independent Variables include Deposits, expense management, credit risk, bank Size, Inflation and Gross Domestic Product has a significant impact on profitability whereas in Model 2 expense management was insignificant
The Critical Impact of Better Civil Services Reforms on the Better Governance of the Country: A Study of Pakistan
Authors: Siddiq Ujala , Khan Zargham Ullah , Aiman Umm e
Published: November 2022

A long history of poor management, rampant corruption, and politicization of civil service has left Pakistan in an economic quagmire, inequitable growth, and political instability. Pakistan’s civil service,by all parameters, has failed to provide effective service delivery and other basic services of public welfare. In the public eye,the country’s civil service officers are seen as non-compliant and least responsive, and uncompassionate behavior coupled with bureaucratic hurdles further aggravate the exploitation of the common masses. The lack of transparency and the military's ability to interfere in the public domain have raised concerns about the state's ability to maintain order. The government should prioritize reforms to transform the Armed Forces into a more effective and efficient organization. Since its inception in 1947, Pakistan has made many attempts to reform civil services, but no real change on the ground calls for turning the elusive dream of civil service delivery into reality. If the flaws of an unreformed bureaucracy remain unaddressed, the government may risk its chances of gaining public support.
A Feminist View of James Joyce's The Boarding House
Authors: Rahman Gohar , Aryan Ayaz Ahmad , Shah Bahramand
Published: November 2022

The theories of feminism have global implications for the due rights of the female gender. Women are exterminated from political, economic, and social circles of life based on gender and they lack opportunities as well. This study aims to analyze James Joyce's The Boarding House against the backdrop of feminism. Joyce points out the sufferings and oppression of women in the male dominant society. Mrs Mooney is the protagonist of the story. Initially, she suffers because of her gender but later on, she achieves independence and emancipation from male dominancy. Thus the character of Mrs Mooney truly depicts the essence of feminism in the story. Similarly, the character Polly faces gender-based discrimination. This study analyzes the sufferings, subjugation, and oppression of women and recommends ways to abolish gender inequality. This study also calls for the emancipation of women and suggests ways to liberate them from patriarchy.
Scientific justification of the perforation methods for Famennian deposits in the southeast of the Perm Region based on geomechanical modelling
Authors: Chernyshov Sergey , Popov Sergey , Varushkin Stanislav , Melekhin Alexandr , Krivoshchekov Sergey , Ren Shaoran
Published: November 2022

The article presents the results of analysing geological structure of the Famennian deposits (Devonian) in the Perm Region. Numerical modelling of the distribution of inhomogeneous stress field near the well was performed for the two considered types of perforation. With regard for the geometry of the forming perforation channels, numerical finite element models of near-wellbore zones were created considering slotted and cumulative perforation. It is ascertained that in the course of slotted perforation, conditions are created for a significant restoration of effective stresses and, as a result, restoration of reservoir rock permeability. Stress recovery area lies near the well within a radius equal to the length of the slots, and depends on the drawdown, with its increase, the area decreases. From the assessment of failure areas, it was found that in case of slotted perforation, the reservoir in near-wellbore zone remains stable, and failure zones can appear only at drawdowns of 10 MPa and more. The opposite situation was recorded for cumulative perforation; failure zones near the holes appear even at a drawdown of 2 MPa. In general, the analysis of results of numerical simulation of the stress state for two simulated types of perforation suggests that slotted perforation is more efficient than cumulative perforation. At the same time, the final conclusion could be drawn after determining the patterns of changes in permeability of the considered rocks under the influence of changing effective stresses and performing calculations of well flow rates after making the considered types of perforation channels.
Bimbingan kelompok dengan teknik permainan simulasi untuk meningkatkan motivasi belajar
Authors: Nur Fadila Syifa
Published: November 2022

Artikel ini merupakan upaya dalam menumbuhkan minat motivasi belajar pada peserta didik. Motivasi belajar merupakan suatu proses internal yang ada dalam diri seseorang yang memberikan gairah atau semangat dalam belajar, mengandung usaha untuk mencapai tujuan belajar, dimana terdapat pemahaman dan pengembangan didalam proses belajar mengajar. Dalam pelaksanaannya artikel ini memanfaatkan dinamika bimbingan kelompok dengan teknik permainan simulasi sebagai upaya yang bisa dilakukan pendidik untuk menumbuhkan minat dalam belajar.
Bimbingan dan konseling menurut m. Quraish shihab Dalam tafsir al-mishbah qur’an surat al-ashr ayat 3
Authors: Fauzan Ibnudin , Evi Aeni Rufaedah  , Desi Angraeni
Published: November 2022

Di era zaman modern ini manusia banyak sekali mengalami permasalahan yang sulit dan kompleks, terkadang manusia ingin keluar dari permasalahan, tetapi muncul permasalahan yang baru sehingga butuh seseorang untuk memberikan arahan, bimbingan, acuan agar dapat menyelesaikan permasalahan didalam kehidupannya. Menurut M.Quraish Shihab dalam Tafsir Al-Mishbah Qur’an Surat Al-Ashr Ayat 3 menjelaskan bahwa sesama manusia harus saling  menasehati dalam hal kebaikan, maka dari itu bimbingan dan konseling sangatlah dibutuhkan dalam hal tersebut. Kajian ini mengkaji tentang bimbingan dan konseling menurut Perspektif Al-Qur’an dalam Tafsir Al-Mishbah Surat Al-Ashr Ayat 3. Pada penelitian ini bimbingan dan Konseling Menurut Perspektif  Al-Qur’an Surat Al-Ashr Ayat 3 adalah berarti suatu aktifitas memberikan bimbingan, pelajaran, dan pedoman kepada individu yang meminta bimbingan (klien)untuk dapat mengembangkan potensi akal pikiran, kejiwaan, keimanan, keyakinan, serta dapat menanggulangi problematika hidup dan kehidupannya dengan baik yang berpandangan kepada Al-Quran dan As-Sunnah.
Sejarah Islamisasi Sains Dan Ilmu
Authors: M.Dimas Maulid
Published: November 2022

Islamisasi Sains merupakan salah satu upaya untuk mengintegrasikan nilai-nilai Islam kedalam ilmu pengetahuan. Islamisasi Sains mengandung tiga makna yaitu: Pendapat pertama beranggapan bahwa Islamisasi ilmu pengetahuan merupakan sekedar memberikan ayat-ayat yang sesuai dengan ilmu pengetahuan umum yang ada (ayatisasi). Kedua, mengatakan bahwa Islamisasi dilakukan dengan cara mengislamkan orangnya. Ketiga, Islamisasi yang berdasarkan filsafat. keempat, memahami Islamisasi sebagai sebuah ilmu pengetahuan yang beretika atau beradab. Dan tujuan dari islamisasi sains adalah berupaya memecahkan masalah-masalah yang timbul karena perjumpaan antara Islam dengan sains modern sebelumnya atau akibat dikotomi antara imu pengetahuan dengan agama yang dipengaruhi oleh paham sekuler atau barat. Progam Islamisasi Sains ini menekankan pada keselarasan antara Islam dan sains modern tentang sejauh mana sains dapat bermanfaat bagi umat Islam.
Pengaruh Model Realistic Mathematic Education Berbantuan Media Audio Visual Terhadap Kemampuan Komunikasi Matematis Siswa Sekolah Dasar
Authors: Nurjanah Erni , Cahyadireja Ardi , Ajmaliah Nisfa
Published: November 2022

Masalah dalam penelitian ini adalah rendahnya kemampuan komunikasi matematis siswa di SD Negeri 2 Kebonpedes. Tujuan dari penelitian ini yaitu untuk mengetahui pengaruh penerapan model Realistic Mathematic Education (RME) berbantuan media audio visual terhadap kemampuan komunikasi matematis siswa sekolah dasar. Penelitian ini merupakan jenis penelitian kuantitatif dengan menggunakan pendekatan eksperimen semu, desain pada penelitian ini menggunakan Nonequivalent Control Group Design. Sampel pertama pada penelitian ini adalah kelas IV SDN 2 Kebonpedes yang berjumlah 25 siswa sebagai kelas eksperimen dan sampel kedua yaitu kelas IV SDN 1 Kebonpedes yang berjumlah 25 siswa sebagai kelas kontrol. Data kemampuan komunikasi matematis siswa diukur melalui instrument tes, untuk menganalisis data dalam penelitian ini digunakan uji statistik yaitu uji independent sample t-test. berdasarkan hasil uji-t menunjukan nilai Sig = 0,000 < 0,05 yang artinya terdapat pengaruh yang signifikan antara model Realistic Mathematic Education (RME) berbantuan media audio visual terhadap kemampuan komunikasi matematis.
Diagnosis Kesalahan Peserta Didik dalam Menyelesaikan Soal Matematika Materi Lingkaran
Authors: Regita Putri Risqia  , Edi susanto  , Ringki Agustinsa
Published: November 2022

Penelitian ini bertujuan untuk: mendeskripsikan jenis-jenis kesalahan dan faktor-faktor penyebab kesalahan yang dilakukan oleh peserta didik dalam menyelesaikan soal matematika materi lingkaran. Jenis penelitian ini adalah kualitatif dengan pendekatan deskriptif. Pengumpulan data dilakukan menggunakan tes diagnostik dan wawancara diagnostik. Subjek penelitian ini ialah kelas VIII-D SMP Negeri 9 Kota Bengkulu yang berjumlah 20 peserta didik. Hasil penelitian menunjukan bahwa: (1) jenis-jenis kesalahan yang dilakukan peserta didik berupa kesalahan konsep dengan rata-rata  peserta didik, kesalahan operasi hitung dengan rata-rata  dan kesalahan prosedur dengan rata-rata , (2) faktor penyebab kesalahan yang dilakukan peserta didik sehingga melakukan kesalahan pada saat mengerjakan soal tes yang diberikan yaitu faktor internal adalah faktor dari dalam peserta didik itu sendiri yakni  meliputi intelegensi, minat dan motivasi, serta faktor eksternal adalah faktor dari keadaan lingkungan peserta didik yakni  meliputi lingkungan keluarga, sarana sekolah dan teman.
Peculiarities of sensitization to milk proteins in healthy babies living in different megalopolises of the Russian Federation
Authors:   Pirogov Russian National Research Medical University, TARASOVA O. V. , DENISOVA S. N. ,   Pirogov Russian National Research Medical University, REVYAKINA V. A. ,   Federal Research Centre of Nutrition and Biotechnology, SAKHAROVA E. S. ,   Pirogov Russian National Research Medical University, SHUMATOVA T. A. ,   Pasific State Medical University, NI A. ,   Pasific State Medical University, MOROZOV S. L. ,   Pirogov Russian National Research Medical University
Published: November 2022

There is no clear answer so far, why, under normal conditions, there is no active immune response to food antigens that are supplied daily with food, while oral tolerance develops in a child. A cohort study of 259 healthy children of the first half year of life who lived in different megalopolises of the Russian Federation showed a high frequency of latent (asymptomatic) sensitization (LS) to milk proteins, which was formed under breast feeding. Despite the transfer to bottle feeding, there was a statistically significant decrease in the frequency of LS to cow and goat milk proteins in babies from Moscow by 5 months of age, and in babies from St. Petersburg by 6 months of age. The frequency of LS to casein, β-LG and α-LA in breastfed babies from Vladivostok during the first three months of life was statistically significantly higher than in babies from Kazan and Khabarovsk during the entire observation period. The data obtained indicate that the immune mechanisms forming latent (asymptomatic) sensitization in the observed children were of an indirect nature, and their implementation was a response to the exposure of maternal allergens that entered the baby’s body in the antenatal and postnatal periods.
Estimation of the antiretroviral therapy effectiveness in HIV / tuberculosis patients based on the lipid spectrum of blood serum
Authors:   Tver State Medical University, MAKAROV P. V. , KRAVCHENKO I. E. ,   Kazan State Medical University
Published: November 2022

Under the ongoing epidemic of HIV-infection, the incidence of tuberculosis continues to grow without a visible tendency to decrease. It is necessary to improve treatment approaches that allow more flexibility in determining the effectiveness of antiretroviral therapy (ART) at the very beginning of treatment for HIV / tuberculosis coinfection. Lipids play an important role in the formation of a tuberculous lesion. The study of the total lipids dynamics in HIV/tuberculosis coinfection has the potential for an early assessment of the ART effectiveness. The purpose is to evaluate the effectiveness of the course of antiretroviral therapy in patients with HIV / tuberculosis at 4B stage based on the values of total serum lipids. Material and methods. The study included 300 patients with HIV / tuberculosis, of which 100 patients received only tuberculosis chemotherapy, 100 patients received ART and 1 TB therapy regimen (TBT), 100 patients received ART and 4 TBT regimen. Clinical and laboratory parameters were studied in all patients, the blood serum lipid spectrum was analyzed (total lipids (OL), total phospholipids (OFL), free cholesterol (CX), cholesterol esters (EH), triglycerides (TG), free fatty acids (FFA)) and the effectiveness of the ART was evaluated. To detect early changes in total lipids, the results were analyzed after 1 month. Results. It was found that ART in HIV/tuberculosis patients causes significant positive changes in the metabolism of total lipids (OL, OFL, CX, EH, TG, FFA), largely bringing their values closer to the level of healthy individuals, which is accompanied by a pronounced clinical and radiological effect in the form of more frequent abacylation. Against the background of ART, an inflammatory immunity restoration syndrome (IIRS) developed, which was stopped by pathogenetic therapy.
Response of using «Uvinskaya» natural mineral water in complex eradication of Helicobacter pylori in patients with chronic gastritis and type 2 diabetes mellitus
Authors:   Izhevsk State Medical Academy, KAZARIN D. D. , SHKLYAEV A. E. ,   Izhevsk State Medical Academy, GORBUNOV YU. V. ,   Izhevsk State Medical Academy
Published: November 2022

The purpose — to assess the effectiveness of therapeutic use of «Uvinskaya» natural mineral water for Helicobacter Pylori eradication in patients with chronic gastritis and type 2 diabetes mellitus. Material and methods. The study included 120 patients with type 2 diabetes mellitus, who were diagnosed with chronic gastritis associated with Helicobacter Pylori. The average age of patients was 61.6 ± 4.13 years, the duration of diabetes — from 2 to 15 years (on average – 9.9 ± 2.5 years), gender composition — 21 men and 99 women. The patients were divided into two groups by simple randomization. In the first group (n = 60), the first line eradication therapy was carried out according to Maastricht V recommendations, in the second group (n = 60) underwent eradication therapy combined with «Uvinskaya» mineral water. The diagnosis of «chronic gastritis» was histologically verified in all patients. The eradication control was carried out 4 weeks after therapy. Changes in the severity of gastroenterological symptoms in patients were determined by the Gastrointestinal Symptom Rating Scale questionnaire. Statistical processing was carried out with the calculation of average values and standard errors of the average. The differences were considered reliable at p ≤ 0.05. Results. The study shows the positive effect of the «Uvinskaya» mineral water inclusion into the Helicobacter Pylori eradication treatment complex in patients with type 2 diabetes mellitus: the condition of patients improved, inflammatory changes in the stomach mucosa were reduced and the efficiency of eradication therapy increased. Conclusion. The amplification of the positive therapeutic effects of drug treatment and drinking balneotherapy provides a significant increase in the efficiency of eradication, improving the clinical course and forecast of chronic gastritis associated with Helicobacter Pylori in patients with type 2 diabetes mellitus. It enables to recommend the intake of «Uvinskaya» mineral water as part of eradication therapy in patients with type 2 diabetes mellitus.
Prevention of subfascial hematomas in caesarean sections and their treatment under the SARS-CoV-2 pandemic
Authors:   Kazan State Medical University, KHASANOV A. A. , RAGINOV I. S. ,   Kazan (Volga) Federal University, TEREGULOVA L. E. ,   Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia, TEREGULOV A. YU. ,   Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia, LISINA M. B. ,   Republic Clinical Hospital, SIRAZEEVA M. R. ,   Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia
Published: November 2022

The article presents data on subfascial hematomas occurring in case of the Pfanennstiel incision. The frequency of hematomas increases in puerperas with coronavirus infection. The latest interim guidelines «Prevention, diagnosis and treatment of a new coronavirus infection (COVID-19) version 15 (02.22.2022)» indicate the need for «an emergency abdominal delivery (caesarean section) taking into account all measures for the prevention of coagulopathic and hypotonic obstetric bleeding». However, no specification is given as to which technique for performing a caesarean section should be followed and what operational access should be carried out for laparotomy of the anterior abdominal wall. Given own experience, the authors believe that under COVID-19, the incision in the anterior abdominal wall should be according to Joel — Cohan technique as the least traumatic and having the fewest post-operational complications. The authors propose methods for diagnosis and treatment of hematomas using highly selective angiography and embolization of damaged vessels. A clinical observation is presented as an example.
Clinical and laboratory characteristics of severe forms of COVID-19
Authors:   Kazan State Medical University, NIKOLAEVA I. V. , GUSEVA S. E. ,   Kazan State Medical University, GATAULLIN M. R. ,   Republic infectious Clinical Hospital named after Prof. A.F. Agafonov, SOZINOVA YU. M. ,   Kazan State Medical University, FATKULLIN B. SH. ,   Republic infectious Clinical Hospital named after Prof. A.F. Agafonov, GAYNATULLINA L. R. ,   Republic infectious Clinical Hospital named after Prof. A.F. Agafonov, SHESTAKOVA I. V. ,   Infectious Clinical Hospital No. 3
Published: November 2022

We analyzed 72 cases of patients with severe and extremely severe forms of COVID-19 and 62 cases of patients with a moderate form of the disease (control group) hospitalized in the Republican Clinical Infectious Diseases Hospital, Kazan, in 2020. Cases were selected by random sampling. Among patients with a severe form of COVID-19 non-working people over 60 years old (79.2%) with concominant pathology (91.7%) prevailed, of which 53% were women and 47% were men. Obesity occurred in 50% of cases, arterial hypertension in 80.6%, diabetes mellitus in 45.8%, coronary heart disease and post infarction cardiosclerosis in 33%, chronic cerebral ischemia — in 11%, chronic kidney disease — in 8.3%, combined comorbid pathology — in 72.2% of cases. The development of severe forms of COVID-19 was not associated with the later terms of patients’ hospitalization or the peculiarities of antiviral therapy at the outpatient stage. 50-69% of patients with COVID-19 received antibiotics unnecessarily at the outpatient stage. Among patients with a severe form of the disease, the temperature was normal or subfebrile in 19.4% of cases. The duration of positive PCR among patients with severe COVID-19 was 10–14 days in 26.3% and more than 15 days in 5.2% of cases. Cardiovascular insufficiency developed in 55.8% of cases, multiple organ failure in 53.5%, acute respiratory distress syndrome in 53% of patients with severe course. Saturation restored in 43% cases of severe COVID-19 within 25 days, in 37% cases desaturation persisted for more than 25 days. Patients with severe forms of COVID-19 had an increased level of C-reactive protein 148.32 (8–497) mg/l, D-dimers 4206.87 (182–30 008) mg/ml, glucose 10.87 (2–37.59) mmol/l, creatinine 137.84 (37–669) mmol/l, neutrophilia 6.64 (1.8–10.5) x 109/l and lymphopenia 2.13 (0.5–3.5) x 109/l. Conclusion. Elderly and obese patients, as well as patients with comorbid pathologies (hypertension, diabetes mellitus, cardiovascular diseases) were more likely to develop severe cases. A significant increase of CRP, D-dimers, glucose, creatinine and lymphopenia were important markers of severe forms of COVID-19.
Modern aspects of urinary tract infection in children: etiology, clinic, diagnosis, treatment and prevention
Authors:   Belarusian State Medical University, BAIKO S. V. , SNOPKOV V. V. ,   City Children’s Infectious Clinical Hospital, VALAKHOVICH V. V. ,   2nd City Children’s Clinical Hospital
Published: November 2022

The purpose — to study the microbial spectrum and sensitivity to antibiotics (AB) of acute and recurrent urinary tract infections (rUTI), to evaluate approaches to the diagnosis, treatment and prevention of acute pyelonephritis (AP) in children in comparison with international guidelines. Material and methods. At the initial stage, the microbial landscape of urine and the antimicrobial sensitivity of uropathogens were assessed in 67 children with AP and in 78 patients with rUTI from January 01 to December 31, 2021. Subsequently, clinical, laboratory and instrumental changes, as well as approaches to treatment and prevention were studied in children with AP. Results. The most common etiological uropathogen of AP and rUTI is E. coli — in 82 and 70% of cases, respectively. The share of febrile infection among patients with AP was 77%. 76% of girls with AP had inflammatory changes in the external genital organs according to the gynecological examination. There is an increase in resistance to the main drugs of etiotropic therapy for AP (cefotaxime, ceftriaxone, amoxicillin/clavulanic acid) and anti-relapse prevention (furazidin). The starting AB in the treatment of AP in 97% of cases was administered intravenously, cefotaxime was used more often (91%). Step therapy was used in 77% of patients. Anti-relapse prophylaxis was carried out in 58% of children, and cefuroxime was prescribed for this purpose in 45% of cases. The recurrence rate of urinary tract infection was 4.5%. Conclusions. Given the regular updating of international recommendations for the diagnosis and treatment of urinary tract infections in children, timely revision and adaptation of local protocols to these changes is required.
DETERMINATION OF THE IMPACT OF FOREST FIRES ON SOIL EROSION RISK BY USING THE ICONA MODEL: A CASE STUDY OF AYVALI DAM WATERSHED
Authors: DUTAL Hurem
Published: November 2022

Soil erosion in dam watersheds is a crucial phenomenon since dams have become a critical component of economic development for many countries. Therefore, the expected increase in both forest fires and heavy rains in the Mediterranean region poses a threat to the dam watersheds. The increase of these two phenomena will cause a serious increase in soil erosion after forest fires in dam watersheds. Therefore, revealing the possible effects of forest fires on soil erosion risk will be extremely beneficial for taking proactive measures in the management of dam watersheds. So, the goal of this study is to reveal the soil erosion risk and to determine the effect of possible forest fires on the soil erosion risk in the Ayvalı dam watershed. The ICONA model was used to reveal the soil erosion risk in the study area. The effect of forest fires was determined by scenario analysis. In the forest fire scenario, it is assumed that all forests in the study area are burned. Considering this scenario, a new soil erosion risk map was produced with the model. Then these two maps were compared. The results showed that 70.33% of the study area faced very high erosion risk, while 21.65%, 7.19%, 0.77%, and 0.05% of it had high, medium, low, and very low erosion risk, respectively. This potentially very high risk results from the steep slopes, high soil erodibility, and sparse vegetation density in the study area. As a result of the fire scenario, it was determined that while the areas with the very high risk increased by 18.11%, areas with high, medium, low, and very low risk decreased by 48.55%, 26.36%, 35.43%, and 100%, respectively. The findings can be a guide for decision-makers to prioritize necessary precautions depending on the soil erosion potential before and after forest fires.
The use of biotransformed spring triticale flour in the technology of bakery products
Authors:   Smolensk State Agricultural Academy, Terentiev S.E. , Bogatyreva T.G. , Labutina N.V. ,   Moscow State Univercity of food production,   Moscow State Univercity of food production
Published: November 2022

The article presents the results of biotechnological research on the adaptation of one of the modern promising grain crops of spring triticale to the technology of baking. The experiment is based on the principles of biotransformation of triticale flour by screening acid-forming microorganisms. The validity of this method is confirmed by indicators of changes in enzymatic and gas-forming activity, as well as data on organoleptic and physico-chemical evaluation of finished products. The use of triticale flour after lactic acid fermentation in the recipe of bakery products allows you to enrich the products with vegetable protein, dietary fibers, micro and macroelements, vitamins.
Obtaining polycomposite flour from processed products
Authors:   Federal State Institution «Scientific and Production Association «Special quipment and Communications» of the Ministry of Internal Affairs of the Russian Federation, Kechkin I.A.
Published: November 2022

Federal State Institution «Scientific and Production Association «Special quipment and Communications» of the Ministry of Internal Affairs of the Russian Federation Bread products occupy upto 40 % percent in the diet of our country,most of them are products based on cereals and various types of flour. To enrich wheat flour with polyunsaturated fatty acids and vegetable protein, white flax and lentil seeds were used, with the addition of no more than 15 %. The grinding of a three-component grain mixture was carried out according to a simplified scheme using a torn and six grinding systems. The scheme of grinding a three-component grain mixture included 1 torn and 6 grinding systems. The grinding products were sorted as follows: a 220 μm sieve was used on 1 torn system, and a 132 μm sieve was used on subsequent systems. In general, the fineness of the flour was characterized by the following indicators: the residue on a sieve of 180 microns is not more than 2 %, the passage of a sieve of 140 microns is at least 80 %, which meets the requirements for wheat flour of the 1st grade. The carried out grinding made it possible to establish that the use of cereals instead of wheat grain leads to a significant simplification of the grinding scheme with a high yield of products. The introduction of flax seeds and lentils into the composition of the grinding mixture made it possible to increase the protein content in flour by about 50 %, and the fat content by 2 times. The learned flour, consisting of 85 % wheat groats, 5 % white flax seeds and 10 % lentils, is a product of increased nutritional value and can be used in the production of bakery and confectionery products.
Reporte de Mercados Financieros - tercer trimestre de 2020
Authors: Vargas Hernando , Cardozo Pamela , Rojas Juan Sebastián , Quicazán Carlos Andrés , Ariza Sara , Barreto Ittza Alejandra , León Laura Viviana , Martínez Diego Alejandro , Mateus Julián Camilo , Ruiz Cristhian Hernando , Venegas Tatiana , Carvajal Hernán Darío , Moreno Daniel Felipe
Published: November 2022

El Banco de la República (BR) genera información para la toma de decisiones, la rendición de cuentas y la difusión al público. En particular, el Reporte de Mercados Financieros está enmarcado dentro del principio de difusión al público y contribuye a cumplir con el servicio que presta el Banco de ofrecer información e investigación económica de calidad.
Reporte de Mercados Financieros - cuarto trimestre de 2020
Authors: Vargas Hernando , Cardozo Pamela , Rojas Juan Sebastián , Quicazán Carlos Andrés , Ariza Sara , León Laura Viviana , Martínez Diego Alejandro , Mateus Julián Camilo , Ruiz Cristhian Hernando , Almario Camilo Eduardo , Quintero-Pacacira Juan Camilo , Salazar-Hernández Juliana
Published: November 2022

El Banco de la República genera información para la toma de decisiones, la rendición de cuentas y la difusión al público. En particular, el Reporte de Mercados Financieros está enmarcado dentro del principio de difusión al público y contribuye a cumplir con el servicio que presta el Banco de ofrecer información e investigación económica de calidad. En línea con lo anterior, este reporte busca proveer al público un análisis general del comportamiento y las tendencias de los mercados financieros nacionales e internacionales.
Reporte de Mercados Financieros - cuarto trimestre de 2021
Authors: Vargas Hernando , Cardozo Pamela , Rojas Juan Sebastián , Quicazán Carlos Andrés , Ariza Sara , Barreto Ittza Alejandra , Herrera Nicolás , León Laura Viviana , Mateus Julián Camilo , Orozco Camilo Andrés , Ruiz Cristhian Hernando , Torres Nicolás Fernando , Lozano Morales Felipe , Morales Pineda Gabriela
Published: November 2022

El año 2021 se caracterizó por una recuperación económica global más rápida de lo previsto a inicios del año. Esta recuperación trajo consigo aumentos en los precios de los commodities y en algunos casos, disrupciones de las cadenas globales de suministro dado la creciente demanda, lo que llevó a un aumento de las presiones inflacionarias a nivel global. Como respuesta a estas presiones, la mayoría de los bancos centrales a nivel global comenzó a retirar el estímulo monetario adoptado durante 2020 para afrontar la pandemia.
Pengukuran Tingkat Risiko Ergonomi Dengan Menggunakan Metode Ovako Working Analysis System (OWAS) Untuk Mengurangi Risiko Muscoleskeletal
Authors: Andrian Deni , Renilaili Renilaili
Published: November 2022

Kenyamanan dalam bekerja merupakan salah satu faktor penting dalam proses produksi. Pada kegiatan industri, paparan dan resiko di tempat  kerja cenderung ada di sekitar tempat kerja dan pekerja. Kondisi tersebut ada kalanya tidak selalu dapat dihindarkan karena tuntutan pekerjaan sehingga membuat karyawan mengalami keluhan pada gangguan otot (musculoskeletal). Hal ini menyebabkan pekerja sering  mengalami keluhan-keluhan pada bagian tubuhnya. Adapun tujuan dari pelaksanaan penelitian ini diharapkan mampu mengidentifikasi postur kerja yang beresiko musculoskeletal. Penelitian ini mengambil sampel pekerja stasiun pengantongan semen. Metode yang digunakan adalah metode OWAS. Hasil penelitian adalah: Terdapat 2 postur kerja di stasiun kerja pengantongan teridentifikasi memiliki potensi menimbulkan cidera musculoskeletal. Hasil analisis OWAS pada postur kerja 1 dan 2 berada pada kategori 2 yang artinya perlu dilakukan perbaikan. Setelah dilakukan perbaikan, maka dari hasil penilaian OWAS terhadap postur kerja 1 dan 2 didapatkan kategori 1 yang artinya tidak ada masalah pada sistem musculoskeletal.
Analisis Penerapan Lean Six Sigma untuk Mengurangi Turn Around Time (TAT) C-CHECK pada Jasa Perawatan Pesawat
Authors: Trenggonowati Dyah Lintang , Umyati Ani , Patradhiani Rurry , Sonda Atia , Sari Febrianti Permata
Published: November 2022

PT. XYZ merupakan perusahaan yang bergerak di bidang jasa maintenance, reparasi dan overhaul pesawat maupun engine pesawat. Waktu Turn Around Time (TAT) digunakan sebagai indikator kinerja pada sebuah perusahaan MRO’s. Turn Around Time (TAT) merupakan interval waktu maintenance yang diperlukan suatu pekerjaan mulai masuk kedalam sistem sampai proses tersebut selesai yang menunjukan suatu siklus kerja. Pada saat proses perawatan yang berlangsung di PT. XYZ umumnya terkadang terjadi deviasi dari TAT atau dengan kata lain pekerjaan mengalami delay, tujuan dari penelitian ini ialah untuk menhindari dan juga meminimasi keterlambatan dari Turn Around Time, maka untuk meminimasi hal tersebut digunakan metode lean six sigma. Dari hasil root cause analysis terdapat tiga faktor utama yang menyebabkan terjadinya keterlambatan dari Turn Around Time yang telah ditetapkan ialah dikarenakan kekurangan manpower, proses menunggu material yang terbagi menjadi dua jenis material yaitu shortage (material dibeli oleh pihak PT. XYZ) dan juga subcont (material yang akan diperbaiki di luar PT. XYZ), dan juga lamanya memproses finding (temuan permasalahan pada saat proses inspeksi), dan dari hasil perhitungan nilai sigma dari proses maintenance yang didapatkan ialah sebesar 2.60? dimana nilai sigma ini setara dengan rata – rata industri di Indonesia,Sehingga dengan perbaikan yang dilakukan diharapkan akan mampu menambah produktivitas serta efisiensi dari proses maintenance yang ada dan juga mampu meningkatkan kepercayaan customer yang akan menambah citra baik bagi PT. XYZ itu sendiri.