bluuebunny/crossref_metadata_2025 huggingface dataset:
Information support of stakeholders in the management of energy systems: development and implementation of interfaces
Authors: Boiko Olha , Shendryk Vira , Parfenenko Yuliia , Pavlenko Petro , Titariev Artem
Published: December 2023

The object of this study is the process of providing informational support to stakeholders of the life cycle of energy to ensure strategic management of energy systems with renewable energy sources. The task to improve and develop information technologies applied to the management of complex energy systems and the issue of their socialization and perception by people were tackled. Considerable attention was paid to the task of data visualization in order to improve the perception of information by users. An important aspect of the interaction of energy life cycle stakeholders during the management of energy systems was explored and the need to ensure their involvement and trust in information technology was emphasized. The research considers the development and implementation of interfaces for a decision support system in the management of energy microgrids using renewable energy sources such as solar panels and wind generators. The results include web application architecture design, user role assignment, user action modeling, and data visualization. Approaches to the distribution of stakeholder authority, database access, interface design and data visualization for full client support were proposed. It is noted that the proposed interface solutions are designed for a decision support system in the management of microgrids with different types of renewable energy sources, such as solar panels and wind generators. Summarizing the results, the relevance of the task to devise methods of information support and interfaces for strategic management of energy systems has been emphasized. The conclusions imply the effectiveness of the proposed solutions for the strategic management of microgrids
Increasing the accuracy of electrostatic fields strength measurement by using an improved differential transimpedance amplifier circuit
Authors: Povcshenko Oleksandr , Bazhenov Viktor , Pazdrii Olha , Bohdan Halyna
Published: December 2023

An electrostatic field mill (EFM) is widely used to measure the strength of electrostatic fields, the main drawback of which is the occurrence of large measurement errors (up to 15 % in the range from 0 to 1 kV/m).
This paper examines the aspects of using transimpedance amplifiers (TIAs) for the tasks of converting the current received from the EFM sensor into voltage, which will make it possible to reduce the instrumental error and ensure the linearity of the atmospheric electrostatic field strength measurement. In the general case, for the functional circuits of the electrostatic field mill, which include a differential transimpedance amplifier, there is the use of two TIA circuits, which are connected in parallel. Despite the simplicity of implementation, such a configuration contains a number of disadvantages and is not optimal. In the paper, a comparative analysis of a typical circuit of a differential TIA and a circuit of an ungrounded differential transimpedance amplifier with zero voltage drop proposed by the authors is carried out.
As a result of the analysis, it was established that the designed authentic circuit of the ungrounded differential transimpedance amplifier with zero voltage drop has better parameters of linearity and interference resistance, in contrast to the generally accepted one. The value of the signal-to-noise ratio for the proposed scheme improved by 42 % on average compared to the typical one. The main difference of the proposed scheme is that the stability of the amplification factor is ensured, the influence of the bias parameters of the operational amplifier is leveled, and the overall noise level is reduced. The use of the designed scheme of an ungrounded differential transimpedance amplifier with zero voltage drop could make it possible to increase the accuracy of the measurement of the electrostatic field strength
Mathematical model for optimization in air traffic scheduling management during the COVID-19 pandemic
Authors: Nasution Darmeli , Mawengkang Herman , Fahmi Fahmi , Zarlis Muhammad
Published: December 2023

In this paper, the object of the study is determining air traffic scheduling management by optimizing mathematical models. The problem in this study is that the COVID-19 pandemic has significantly disrupted air traffic, resulting in changes to regulations, travel restrictions and a decrease in passenger demand. One of the problems that must be resolved is how to organize and adapt flight schedules to current conditions by focusing on mathematical models that are used to optimize or increase the efficiency of managing flight schedules or air traffic. Mathematical models can help find ways to optimize the use of available resources, such as airport capacity, flight routes and flight frequency. The results obtained in this research are a mathematical model that specifically takes into account the variables involved in setting air traffic schedules during the COVID-19 pandemic so that capacity limits at airports and airspace are always normal. An optimization model was developed from previous research, namely the model that takes into account ground and air delays as well as the use of alternative paths and avoids deviations from the initial more accurate flight plan, which overall indicates that the maximum time and maximum distance values for each item have been optimized to achieve better values. This research has the novelty of producing a mathematical model using variables, objective functions, capacity limits, flight structure limits and variable domains, which then produces an algorithm with data input processes, determining optimization models, determining variables, determining objective functions, determining problems. The results of this model can be recommended to airlines in scheduling flights during the pandemic
Modification of the ontology using the teacher’s personal materials to increase the degree of automation of EC preparation
Authors: Sabitova Nazym , Tikhonov Yuriy , Lakhno Valerii , Niyazova Rosamgul , Razakhova Bibigul , Zholdasova Sholpan , Ospanova Tleugaisha , Taimuratova Lidiya
Published: December 2023

The object of the research is the technology of constructing a computer ontology (CO) for electronic textbooks of the subject area (KSA). As an example, the industry is considered-information and communication technologies (ICT) and the topic "databases".
The subject of the study are models and methods of automated construction of a CO of the KSA.
The methodology of modification of CO in the field of ICT is proposed by introducing into the formal computer ontology a description of the technologies of the learning process for secondary schools or extracurricular institutions, as well as for professional retraining of specialists, which allows preserving and reusing the collective experience of learning in an educational institution.
The proposed solution differs from the existing ones in that the system of ontologized design of electronic courses (SODEC). It allows to automate the development of electronic courses (EC) and / or electronic textbooks (ET), reduces the cost and time of preparing ET, ensures compliance of EC with the current state in the field of ICT. As an example, the design section of ET for the topic "databases" is considered. The proposed solution allows to accumulate personal materials of the teacher and contributes to the rapid updating of the content and content of ET, if necessary. It is concluded that for more effective use of the proposed methodology, it is necessary to develop a similar SODEC, taking into account the language of description of CO – OWL, which will allow to accumulate collective experience in the methods of submitting material to teachers of educational institutions or extracurricular institutions, as well as during professional retraining of specialists
Atrial Fibrillation after COVID-19 Vaccination in an Adolescent: A Case Report
Authors: Seo Min Kyu , Lee Sun Hyang
Published: December 2023

Several cases of cardiac arrhythmia after coronavirus disease 2019 (COVID-19) vaccination have been reported in adults. However, the Centers for Disease Control and Prevention do not list cardiac arrhythmias as a possible side effect of the COVID-19 vaccines. A previously healthy 18-year-old man presented at the Soonchunhyang University Bucheon Hospital with complaints of palpitations, acute chest tightness, and dyspnea. Two days before presentation, he had received the COVID-19 vaccine, BNT162b2 (Comirnaty, Pfizer-BioNTech; Pfizer, New York, NY, USA). His vital signs were stable; however, physical examination revealed irregular heartbeats without a cardiac murmur. A 12-lead electrocardiography showed atrial fibrillation. The patient received several medications for 6 months, without improvement. Eventually normal sinus rhythm was restored with cardioversion. The patient has remained asymptomatic for 1 year. We report the case of an adolescent with atrial fibrillation after receiving a messenger RNA COVID-19 vaccine. Atrial fibrillation should be considered a cardiovascular side effect of the COVID-19 vaccine in adolescents.
A Case of Repeated Intravitreal Dexamethasone Implantation for Treatment of Macular Edema after Scleral Fixation of Intraocular Lens
Authors: Sun Hae Jung
Published: December 2023

The purpose of this case was to report a case of repeated dexamethasone intravitreal implant (Ozurdex; Allergan Inc., Irvine, CA, USA) migration into the anterior chamber without any corneal complications in a patient with cystoid macular edema. A 70-year-old male patient had decreased vision due to cystoid macular edema after scleral fixation of a dislocated intraocular lens in his right eye. He had repeated intravitreal bevacizumab injection but macular edema showed little improvement. Macular edema improved after intravitreal dexamethasone implantation but he needed repeated implantation since macular edema recurred as the therapeutic effect of the implant decreased. After the third implantation, 70 days later, the implant was observed in the anterior chamber, and the intraocular pressure (IOP) measured 46 mm Hg, while the cornea remained clear. We decided to have a close follow-up with IOP control since no corneal edema was seen. The implant was completely absorbed after 40 days with clear cornea and another intravitreal dexamethasone implantation was performed owing to increasing macular edema. The implant was seen in the anterior chamber again after 78 days but no corneal edema was seen and IOP was normal. After 1 month the implant was completely absorbed and intravitreal dexamethasone implantation was repeated. Migration of dexamethasone intravitreal implant may happen in a patient with posterior capsular defect but the treatment could be maintained under close observation in absence of corneal complications.
The Significance of Philosophical Anthropology in Determining the Methodology of Modern Scientific Research
Authors: Kubalskyi O. N.
Published: December 2023

Purpose. This research involves revealing the methodological significance of the anthropological understanding of values for conducting modern scientific research. Theoretical basis. Philosophical anthropology acts as an epistemological basis for answers to ontological questions that are part of the structure of such problems in modern science as the construction of a scientific picture of the world, the ordering of data of natural attitude, and anthropocosmism. The ontological basis for the formation of the anthropological theory of values is the teaching of Wilhelm Leibniz, Immanuel Kant, Rudolf Lotze, and Martin Heidegger. Originality. The creation of a scientific picture of the world, the research of natural attitude, and an anthropological approach to cosmology carried out from the viewing angle of the philosophy of values show the close mutual conditioning of these scientific issues. A successful determination of one’s value positions by a scientist-researcher is impossible without his/her agreeing with his/her picture of the world with the prevailing ideas about the world in their society. Such ideas are studied by anthropocosmism, which researches not so much the world in itself, but a view of this world from the standpoint of the existing state of society and the main intentions of its development. Conclusions. The value attitude of scientists at a certain stage of the development of scientific knowledge forms their picture of the world, which has the form of self-explanatory scientific provisions. The facts of modern physics must always, one way or another, receive their legitimation through the world of the human natural attitude. Even the unobservable characteristics of the microcosm are explained by appealing to knowledge about the observable characteristics of the world. The anthropocentric nature of cosmology is determined by the fact that in modern philosophy, the values of a person explain not only the way of one’s cognition but also the way of one’s inclusion in the world.
Fatigue life of unified riveted superstructures designed by Transmostproject with the introduction of increased axle loads
Authors: Feoktistova Elena
Published: December 2023

The article presents a study of the residual fatigue life of superstructures during the introduction of trains with increased axial loads on bridges with riveted superstructures, designed in the fifties of the last century. Unified metal superstructures have been in relatively heavy duty conditions for more than 60 years. During lcontinuous operation, processes occur in elements and joints that lead to the appearance and development of various damages and varying degree failures of hazard, so it is necessary to decide on the further operation of old bridge spans and their replacement.

When determining the fatigue life, the linear addition hypothesis of fatigue damage accumulation was used, taking into account the increase in stresses with the introduction of increased axial loads. As a critical measure of damage, providing a given reliability, the value obtained from the calculation results of several hundred cracks in riveted superstructures of older design standards was adopted. The increase in load from the installation of a ballastless bridge floor is taken into account. To determine the residual fatigue life, fatigue data is used depending on the concentration of stresses magnitude in the attachments of the main truss elements.

For a more accurate determination of the rivet joints operation stage, the author carried out a wear-out calculation through operation period. The introduction of heavier train loads will lead to an increase in the accumulation of fatigue damage in the elements. If weak rivets in attachments are found during inspection, they must be replaced with high-strength bolts to increase fatigue life. The author obtained that the residual fatigue life of the span structures designed by Transmostproekt has not yet been fully exhausted even with the introduction of heavy trains with a wagon axle load of 27–30 tons.
MACHINE LEARNING LOCAL WALL STEAM CONDENSATION MODEL IN PRESENCE OF NON-CONDENSABLE FROM TUBE DATA
Authors: Sharma Pavan K.
Published: December 2023

During a severe accident in nuclear reactors, steam condensation on containment structures is an important
phenomenon that may affect the local concentration of hydrogen and the location of flammable regions in the
nuclear containment. Accurate predictions of steam condensation rates and thereby peak hydrogen concentrations,
temperature, and pressure rise in containment require the use of computational fluid dynamics (CFD) tools. The
popular regulatory CFD calculations require a local heat transfer coefficient (HTC) at small, discretized length scales.
In a classical three-dimensional full CFD, the HTC requirement can be eliminated, but for large structures and
finely resolved multiscale calculation it may not be possible. This paper presents the development of two different
kinds of local condensation HTC models for tube-based geometry based on (i) the machine learning (ML) model and
(ii) the conventional third-order polynomial regression model. An extensive literature review was utilized to collect
the data from various open literature sources. This eliminates the limitations of individual correlations and gives
a best optimized model, which is valid for a wide range of flow regimes and conditions as compared to a specific
correlation. Application of bulk HTCs for smaller tube as a local wall HTC is explored. Various simple ML models
are compared for their performance against test data, and a multivariate adaptive regression splines (MARS)-based
model was finally adopted for application and detailed discussion. The present ML was developed on the Python
language framework. The MARS model was compared against the data, which was not used for the training and
conventional polynomial based correlation. For traditional containment safety applications, both models were found
to be suitable based on present studies.
All-Union / All-Russian: Unrealized Project of the Soviet Society for Monuments’ Protection
Authors: Boltunova E. M. , Egorova G. S.
Published: December 2023

The All-Russian Society for the Protection of Historical and Cultural Monuments was established in 1965. It was preceded by almost a ten-year period of massive public and institutional lobbying. The public movement started with a proposal to create an all-union Society in 1956, but this idea was never implemented. The article deals with the development of the all-union and all-Russian projects, showing the connection between them. The authors also research the stages of the projects’ institutional promotion and suggest why the all-union Society was never created
Evaluation of the Prediction Algorithms for the Diagnosis of Hepatic Dysfunction
Authors: ARPACI Saadet Aytaç , VARLI Songül
Published: December 2023

Acute liver failure develops due to liver dysfunction. Early diagnosis is crucial for acute liver failure, which develops in a short time and causes serious damage to the body. Prediction processes based on machine learning methods can provide assistance to the physician in the decision-making process in order for the physician to make a diagnosis earlier. This study aims to evaluate three recently presented algorithms with high predictive capabilities that can assist the doctor in determining the existence of acute liver failure. In this study, the prediction performances of the XGBoost, LightGBM, and NGBoost methods are examined on publicly available data sets. In this research, two datasets are used; the first dataset was gathered in the “JPAC Health Diagnostic and Control Center” during the periods 2008–2009 and 2014–2015. The dataset includes a total of 8785 patients' information, and it mostly does not contain patients' information that "acute liver failure" was developing. Furthermore, a dataset collected by Iesu et al., containing information on patients who developed or did not develop "acute liver dysfunction," is used for the second evaluation. According to the information obtained from the data set, "acute liver dysfunction" developed in 208 patients, while this situation did not develop in 166 patients. It is observed within the scope of the evaluations that all three algorithms give high estimation results during the training and testing stages, and moreover, the LightGBM method achieves results in a shorter time while the NGBoost method provides results in a longer time compared to other algorithms.
CALCULATION OF AN ALTERNATIVE DEVELOPMENT SYSTEM FOR THE MAIN DEPOSIT OF THE DANILOVSKOYE OIL AND GAS CONDENSATE FIELD
Authors: Chasovskikh O.A. , Motorova K.A.
Published: December 2023

The article provides a calculation of an alternative development system for deposit 3 (Main deposit ) of the Danilovskoye oil and gas condensate field. At the time of the analysis, this deposit is in the pilot development stage, with six development variants proposed in the trial operation project, which assume a principled arrangement of wells along an areal homogeneous grid. At the same time, due to the need to maintain the energy of the formation (that is, certain values of thermodynamic conditions), three provide for a transition to pressure maintenance, with the resulting four-point scheme of effect on the deposit (intensity 1:2; one well for injection, two for production). In the alternative model under consideration, the development method also involves a subsequent transition to pressure maintenance, but with a more active, five-point waterflooding system (intensity 1:1, equal ratio of production and injection wells), if necessary, as will be shown in the work, easily convertible to a nine-point one. The latter is an objective advantage, since the formation has low permeability and high vertical and lateral heterogeneity, and during waterflooding, zones not affected by the impact may appear, and, consequently, zones with high residual oil saturation. When calculating the characteristics of the proposed alternative method, modeling using the Peaceman method is used. Peaceman’s method is based on determining the well-reservoir connectivity of each individually opened cell, used to calculate flow rates (taking into account different values of average water cut for wells). The method is classical and, although it includes a large number of limiting assumptions, it is applicable everywhere and can provide sufficient justification for the effectiveness of the chosen development variant. General recommendations for the development of the entire field are also given (taking into account the low viscosity and lightness of oil and the properties of reservoir rocks). Such as the use of acid fracturing technology, the use of surfactants, hydrochloric acid treatments (HAT) and a complexing phosphorus-containing reagent — AFC.
THE DEPOSITIONAL SETTINGS AND THE HYDROCARBON POTENTIAL OF THE NEOTETHYS PASSIVE CONTINENTAL MARGIN
Authors: Suleymanov D.D. , Rykus M.V.
Published: December 2023

The study area is associated with the outer passive wing of the foreland trough that was formed due to collisional-orogenic deformations of the Neotethys Arabian Plate. The sedimentological and paleoenvironmental features of the Cenomanian formation indicate that the carbonate sediments were deposited in a homoclinal ramp depositional settings. The depositional area comprises different bathymetric settings from the intertidal littoral and coastal shallow water to the open and relatively deep sublittoral. Microfacies analysis was performed based on the cores and thin sections observations to investigate the sedimentary and diagenesis evolution. Ten microfacies types are identified showing that carbonates deposited in three major sedimentary facies belts: outer ramp, middle ramp and inner ramp. In response to the relative sea level changes during sedimentation the section comprises of several sedimentary sequences. The sequences mainly reflect the prevailing of twocomponent depositional pattern, i.e., middle ramp and outer ramp, which is a result of low fluctuation of the relative sea level. The complete three-component sequences are associated with predominantly shallow areas that favorable for progradation event even under the low fluctuations of the relative sea level.The highest sedimentation rate is confined to the proximal shallow part of the middle ramp and to the distal part of the inner ramp with favorable conditions for the development of benthic organics due to abundant sunlight and nutrition supply. The best reservoir rocks with intergranular voids, composed of algal oolitic and bioclast grainstones of high dynamic shoal zone.This study provides an insight into reservoir quality prediction and prospect area evaluation of the oil bearing formation in the southern part of stable shelf which is controlled by spatial extension of grain supported deposits of inner ramp and transverse faults.
PROCEDURE FOR DESIGN OF DOWNHOLE DAMPING DEVICES USING ELASTOMERS
Authors: Yakhin R.R. , Zubairov S.G. , Salikhov T.I.
Published: December 2023

The article is devoted to the problem of combating vibration and shock loads in the oil production industry. Described is a method of reducing loads due to the use of dampers in the design of devices. It is indicated that for damping vibration loads in mechanical engineering a wide range of design solutions is used using hydraulic, pneumatic and mechanical systems and devices. The article compares the use of springs and elastomers as a damping element in mechanical structures of downhole devices. It is also indicated that it is recommended to use experimentally obtained dependencies to select the damping material of the elastomer: with vibration of forced vibrations from 13.5 to 23.5 Hz, the density of the material should be increased, and with forced vibrations from 25 to 50 Hz, on the contrary, the density of the material should be reduced.As a vibration-isolated object, the article considers the installations of electrically driven centrifugal pumps (ESP), in which, due to unstable operating conditions, modules are often divided with a fall («flight») at the bottomhole due to fatigue destruction of the connecting elements. Two patented structural solutions to combat vibration and impact loads due to inclusion of a damping module with an elastomer substrate made in one case with an external conical surface and in the other in the form of a cylindrical bushing are presented.In recent years, there has been a trend towards a decrease in the diameter of wells and, accordingly, casing pipes. Therefore, an ESP arrangement with a damping module with a substrate made in the form of a cylindrical sleeve is most acceptable. Since in this design it is possible to increase the damping capacity of the module by increasing the thickness of its substrate.For this damper design, a method for calculating the relative longitudinal compression strain of its elastic substrate has been developed. It is shown that in order to ensure radial extension of levers by the required value, it is necessary and sufficient to determine the maximum diameter of the deformed (compressed) cylindrical rubber bushing, which at the same time acquires a barrel-like shape with a curvature of the generatrix depending on the rubber material: density and tightening factor.
ASSESSMENT OF THE POSSIBILITY OF EXPLORING THE WELL'S BACKWATER SPACE BY ACTIVE THERMOMETRY
Authors: Ramazanov A.Sh. , Sharafutdinov R.F. , Islamov D.F. , Akchurin R.Z.
Published: December 2023

The use of active thermometry based on local induction heating of the casing string has prospects for solving environmental problems in the study of idle wells. With an inductor power of 1 kW, even with small heating times, it is possible to create and register temperature anomalies in the casing.This article explores the possibility of using active thermometry to solve environmental problems in the study of idle wells.The idea is to measure the temperature of the casing before and after heating by the inductor for a certain time. Obviously, with fixed inductor power and heating time, the change in temperature of the section of the casing string heated by the inductor will depend on the heat exchange between the casing string, the downhole environment and the environment in the annular space. In this case, the conditions of heat exchange with the down hole environment at different depths may remain the same, but with the external environment surrounding the column may change. The reason for this may be a change in the contact of the column with the cement, the properties of the cement, the presence of vertical or horizontal fluid flows behind the well, etc.The paper presents a new analytical solution for calculating unsteady temperature in a metal casing caused by induction heating of a section of the column. The solution is based on a one-dimensional analytical model that takes into account heat exchange between the fluid and the casing, heat generation in the metal column when the inductor is turned on, and heat conduction losses in the cement and rock. To obtain a solution, the Laplace integral time transform method was used.The results of the study show that the amount of heating of the column changes depending on changes in heat exchange conditions and changes in the thermal activity of the environment behind the column. Significant differentiation of temperature along the depth of the well can be caused by a violation of the tightness of the cement ring, the movement of formation water and annular flow. This creates the prerequisites for using the active thermometry method to solve environmental problems in developed oil fields.
Çevre Bilinci, Çevresel Duyarlılık ve Doğaya Bağlılık: Öğretmenler Üzerine Bir İnceleme
Authors: GÜRER Burak , MERMER Kadriye Kübra
Published: December 2023

Son yıllarda hızla artan çevre, doğa sorunları ve bireysel davranışlar araştırmacıların dikkatini bu yöne çekmiştir. Buradan hareketle, araştırmanın amacı eğitim sürecinin en önemli parçalarından biri olan öğretmenlerin çevre bilinci, çevresel duyarlılık ve doğaya bağlılık davranışlarının ortaya konmasıdır. Araştırmanın evrenini Gaziantep ilindeki öğretmenler, örneklemi ise rastgele örneklem yolu ile seçilmiş 634 öğretmen oluşturmuştur. Veri toplama araçları olarak Yeşilyurt, Gül ve Demir (2013) tarafından geliştirilen “Çevre Bilinci ve Çevresel Duyarlılık Ölçeği” ve Mayer, F. S., ve Frantz, C. M. (2004) tarafından geliştirilen Türkçe uyarlaması Bektaş, F., Kural, B., & Orçan (2017) tarafından yapılan “Doğaya Bağlılık Ölçeği” kullanılmıştır. Verilerin analizinde bağımsız örneklem t testi, tek yönlü varyans analizi ve Pearson Korelasyon analizi kullanılmıştır. Elde edilen bulgulara göre, cinsiyet değişkeninde çevresel duyarlılıkta, yaş değişkeninde ise çevre bilincinde anlamlı farklar bulunmuştur. Branş değişkenine göre doğanın parçası, çevre bilinci ve çevresel duyarlılıkta; spor deneyimine göre ise doğa ile bütünleşme ve doğanın parçası alt boyutlarında anlamlı farklar tespit edilmiştir (p<0.05). Sonuç olarak, öğretmenlerin doğaya bağlılık ile çevre bilinci ve çevresel duyarlılık durumlarının genel olarak orta seviyelerde olduğu söylenebilir. Doğaya bağlılık ve çevresel sorunların çözümü için geliştirici seminerlerin yapılması önerilmektedir. Doğa temelli spor aktiviteleri ile çevresel duyarlılık ve bilinçlendirme çalışmaları yapılabilir.
Sakarya İli Poyrazlar Gölü Tabiat Parkının Sportif Rekreasyon Potansiyelinin Belirlenmesi
Authors: ŞEN Murat , ECE Cuma , ÜNSAL Gülşen , ÇALIK Fehmi
Published: December 2023

Sanayi devriminden sonra insanlar yoğunlaşan iş hayatı ve nüfus artışı sonucu büyük şehirlere sıkışmıştır. Bu sıkışma, bireylere zihinsel ve fiziksel olarak negatif tarzda tesir etmiştir. Bu negatif etkilenmenin bir sonucu olarak bireylerin açık hava rekreasyon etkinliklerine olan ilgisinin artması ile Milli parklara ve tabiat parklarına olan ilgi de artmıştır. Günümüzde bu alanlar birçok insan tarafından rekreatif ya da turistik faaliyetlerde bulunmak için ziyaret edilmektedir. Tabiat alanlarının korunması ve toplumun faydası gözetilerek sürdürülebilir bir tarzda kullanılması çok önem kazanmaktadır çünkü rekreatif faaliyetler gittikçe gelişmekte, çeşitlilik kazanmaktadır ve tabiat alanları rekreatif ya da turistik etkinlikler bakımından çok önemlidir. Bu bakımdan araştırmamız, Sakarya’ da bulunan Poyrazlar Gölü Tabiat Parkı’nın sportif rekreasyon potansiyelini değerlendirmek için yapılmıştır. Araştırmada yöntem olarak Gülez’in 1990 senesinde geliştirdiği ve Çalık tarafından 2006’ da modellenen sportif rekreasyon potansiyeli değerlendirme yöntemi kullanılmıştır. Araştırmada göl sahasının incelenmesi safhasında, Sportif Rekreasyon Değeri (SRD), Peyzaj Değeri (P), İklim (İ), Ulaşılabilirlik (U) ve Olumsuz Etkenler (OSE), yapılan değerlendirmede kriterler olarak kullanılmıştır. Yapılan araştırmanın sonunda; Poyrazlar Gölü Tabiat Parkı doğal kaynak değerleri ve açık alan sportif rekreatif potansiyel değeri bakımından %77 bir oranla çok yüksek olarak tespit edilmiştir. Bu sonuca göre, Poyrazlar Gölü doğal kaynak değerleri ve açık alan sportif rekreatif potansiyel değeri bakımından çok yüksek potansiyele sahiptir. Poyrazlar Gölüne ait doğal kaynakların sportif kullanımına göre uygunluğu ise şu şekilde sıralanmaktadır: doğa yürüyüşü, dağ bisikleti, kano, paintball, ATV aktiviteleri, alandaki kuşların gözlenmesi, sportif anlamda balıkçılık ve fotoğrafçılık bölge yapısıyla en uyumlu açık alan sportif rekreatif aktiviteler olarak görülmektedir.
Exploring challenges and opportunities in detecting emerging drug trends: A socio-technical analysis of the Canadian context
Authors: Bouchouar Etran , Levine Marissa J. , Ileka-Priouzeau Samuel , Dave Sailly , Fu Allan , Salemi Jason L.
Published: December 2023

Objectives

This study aimed to apply a systems thinking approach to explore factors influencing the detection of emerging drug trends in Canada’s provinces and territories to better understand how the local context can influence the design and performance of a pan-Canadian (i.e., national) substance use early warning system (EWS). This study also presents a set of actionable recommendations arising from the results.

Methodology and methods

Semi-structured interviews were conducted with 13 purposively recruited Medical Officers of Health and epidemiologists from across Canada working in the field of substance use. Thematic and social network analysis guided by the socio-technical systems framework were subsequently employed.

Results

Barriers and facilitators for detecting emerging drug trends in provinces and territories are a product of the collective linkages and interactions between social (objectives, people, culture), technical (tools, practices, infrastructure), and external environmental (financial, regulatory frameworks, stakeholders) factors. Shortcomings in several of these areas shaped the system’s behaviour and together contributed to fragmented operations that lacked strategic focus, poorly designed cross-sector partnerships, and unactionable information outputs. Participants’ experiences shaped perceptions of a national substance use EWS, with some voicing potential opportunities and others expressing doubts about its effectiveness.

Conclusion

This study highlights interconnected social, technical, and external environmental considerations for the design and implementation of a national substance use EWS in Canada. It also demonstrates the value of using the socio-technical systems framework to understand a complex public health surveillance issue and how it can be used to inform a path forward.
Мотивы волонтеров: контексты до и во время пандемии COVID-19
Authors: Саблина Светлана , Трусевич Александр , Каплий Наталия
Published: December 2023

Волонтерское движение всегда было значимым инструментом помощи нуждающимся, как в повседневных, так и в чрезвычайных ситуациях. Целью данного исследования является изучение мотивов добровольчества в России до и во время пандемии COVID-19, опираясь на теоретические рамки постмодерна. Мотивы волонтеров оценивались через ретроспективную рефлексию информантов и оправдание своего поведения. Исследовательский вопрос: заключается в том, как волонтеры описывают и оправдывают мотивы (не)участия в формальном и неформальном добровольчестве до и во время пандемии. Основным методом сбора информации выступил метод нарративного интервью. Мы побеседовали с 25 российскими волонтерами в 2019г. и 30 в 2021г. Проанализированные с помощью тематического анализа транскрипции интервью, позволили углубить понимание широкого спектра мотивов волонтеров, как альтруистические, так и прагматические, в контексте краткосрочного влияния пандемии. Исследование выявило специфику «пандемического» волонтерства, его тесную связь с повседневной жизнью. Также были обнаружены новые аспекты мотивов (не)участия, актуальные для пандемии, и которые могут быть идентифицированы как контекстно-зависимые. Работа предлагает пример методологического подхода, полезного для изучения мотивов добровольцев, особенно в контексте пандемии или кризиса.
THE EFFECTS OF COMBINATION OF RADIOFREQUENCY AND PULSED MAGNETIC FIELD ON CAROTID ARTERIA ISCHEMIA AND REPERFUSION INDUCED BRAIN INJURY: A PRELIMINARY REPORT
Authors: TANER Rümeysa , AŞÇI Halil , UYSAL Dinçer , AŞCI Sanem , DOĞAN ÜNLÜ Melike , OĞUZOĞLU Ali Serdar , ÇÖMLEKÇİ Selçuk , ÖZMEN Özlem
Published: December 2023

Objective

Cerebrovascular accident due to ischemia (IS)

mediated by atherosclerotic plaque in the brain

can trigger inflammation in the cerebral cortex,

hippocampus and cerebellum tissues. Radiofrequency

electromagnetic field (RF-EMF) and pulsed magnetic

field (PMF) applications can increase nitric oxide

formation from the vascular endothelial layer. The

aim of this preliminary study is to reduce the damage

caused by IS in different tissues of the brain by

magnetic field applications.

Material and Method

A total of 9 rats, one rat in each group; sham,

prophylactic RF, PMF, RF+PMF and therapeutic

RF-EMF, PMF, RF-EMF+PMF, prophylactic and

therapeutic RF-EMF+PMF and IS-only groups were

distinguished. In single or combined applications of

prophylactic/therapeutic RF-EMF and PMF groups,

rats were taken to the experimental unit for 30

minutes of magnetic field exposure before and after

30 minutes of carotid artery occlusion for IS purposes.

Histopathological hematoxylin-eosin staining in

brain tissue (cerebral cortex and hippocampus)

and cerebellum tissues taken after sacrification;

With immunohistochemical analysis, brain derived

neurotrophic factor (BDNF), tumor necrosis factoralpha

(TNF-α), mammalian target of rapamycin

(mTOR) and inducible nitric oxide synthase (iNOS)

expressions were examined.

Results

Histopathologically significant hyperemia, edema,

bleeding and neuronal degeneration were detected

in the IS group. Additionally, immunohistochemically,

an increase in TNF-α, mTOR, iNOS and a decrease

in BDNF staining were observed. Prophylactic and/or

therapeutic RF-EMF and/or PMF applications reversed

all these parameters. The greatest improvement

was observed in the Prophylactic+Therapeutic RFEMF+

PMF group.

Conclusion

As a result, the regression of IS-related inflammation in

both brain tissue parts and cerebellar tissues with RFEMF

and PMF is important in terms of the formation

of neurological deficits, the continuity of learning

and memory mechanisms, and the preservation of

balance functions.
Human effects of lindane in a one health perspective. A review
Authors: Gabriele Arnesano , Marco Merella , Igor Meraglia , Agostino Messineo , Margherita Pallocci , Paolo Maurizio Soave , Michele Treglia , Nicola Magnavita
Published: December 2023

Lindane or gamma-hexachlorocyclohexane is a chloro-organic insecticide marketed since 1938. The demonstration of significant toxic effects for humans, including neurological, hepatic, hematological, and carcinogenic effects, led to its ban. Since 2000, the use of lindane has declined, but attention to the possible effects on public health must remain high, given the bio persistence of the toxicant. The purpose and aim of this study were to recapitulate the effects that lindane may have on humans, based on a review of the literature. The results indicate that, despite the many years that have passed since the demonstration of the toxic effects of lindane, the high persistence and accumulation of the substance in ecosystems, make it even possible that it plays a role in the genesis of chronic degenerative diseases. The connection between human, animal, and ecosystem health which is contained according to the World Health Organization in the “One Health” model, urges us not to slow down our vigilance on these substances.
DoTA-seq V3.1 v1
Authors: not provided freeman.lan
Published: December 2023

This protocol describes the process of DoTA-seq generating a single cell sequencing library from a cell suspension. This workflow can be performed in two days, with the PCR step happening overnight. Before beginning this workflow make sure to have: 1. The necessary microfluidics devices prepared and ready to go 2. The multiplex DoTA-seq target primers validated to work together without generating large molecular weight primer dimers. Please read the publication for further details.
Comparison of values of crestal bone loss around dental implants: A comparative study
Authors: Ajanović Muhamed , Kamber Alma , Tosum Pošković Selma , Dervišević Almir , Tucak Kemal
Published: December 2023

Introduction: Many studies have examined values of crestal bone loss according surgical techniques, time of implant placement (immediate post-extraction or after alveolar socket healing), platform switching or convectional platform, surface of the implant, functional loading (immediate or delayed), etc.
Methods: This study analyzed a total of 443 dental implants on 115 images: 161 Bredent blueSKY dental implants and 282 Ritter spiral dental implants. All images were taken at the Faculty of Dentistry of the University of Sarajevo: before implantation and after 1 year of functional loading. Crestal bone loss was measured on the mesial and distal side of each implant from the coronal portion of the abutment to the noticeable margin of the alveolar bone.
Results: There is statistically significant differences between Bredent blueSKY and Ritter spiral dental implants regarding mesial (p < 0.001, df = 441, tstat = −64.22) and distal (p < 0.001, df = 441, tstat = −151.21) bone losses.
Conclusion: Platform switching dental implants showed more bone loss on the mesial and distal side of implant than dental implants with conventional platform.
Tested by the Polycrisis: Reforming or Transforming the EU?
Authors: Bressanelli Edoardo , Natali David
Published: December 2023

This thematic issue addresses the question: To what extent have the latest crises—the pandemic crisis and Russia’s war in Ukraine—triggered institutional and policy change in the EU? It contributes to the literature on the impact of crises on integration and the EU political system, presenting new research based on fresh theoretical insights, empirical data, or a combination of both. Theoretically, the contributions collected in the thematic issue explore whether the crises represent a critical juncture for the EU, leading to institutional and/or policy innovations or, rather, set in motion more incremental processes of adaptation. Empirically, all articles—some of which are qualitative, while others are quantitative—are based on original or new data. The first group of contributions deals with institutional change, focusing both on formal (i.e., treaty reform) and informal (i.e., codes of conduct) institutions. A second group moves the focus to policy change, looking at the impact of the Covid-19 pandemic on several policy areas and the energy crisis. Overall, the key lesson is that the EU can now manage and absorb new shocks quite effectively. At the same time, however, it does not promote ambitious and coherent political models or policy paradigms. Instead, it provides room for experimentation through patchwork-like strategies where old and new instruments and settings mix.
An interesting parameter deduced from confirmed infection number in COVID-19 epidemic
Authors: CL Chow , CH Cheng , WK Chow
Published: December 2023

In controlling outbreaks of COVID-19, the number of daily confirmed infected cases is useful in deducing parameters to determine emergency management actions such as locking down the cities. However, complicated mathematical models with ordinary differential equations are involved. Resources including manpower and data accessibility are needed. The parameters deduced are always challenged by stakeholders, particularly those from servicing and tourist industry. A simple parameter is proposed to describe the extent of infection by estimating the transient daily infection number divided by the time. The daily infection number in Hong Kong is used to illustrate the approach. This will not require large-scale long-term observation and mathematical modeling or computation. Keywords: COVID-19; infection number; parameter
Tumor budding in colorectal adenocarcinoma using cytokeratin 20 immunostaining
Authors: N Chaitra , RNS Sundar , HKS Kumar , G Nataraju , KB Esaivani
Published: December 2023

Introduction: Colorectal cancer is the third most common cancer worldwide and second most common fatal cancer. Tumor budding is an emerging prognostic indicator in cancers. Though tumor budding can be assessed using Hematoxylin and Eosin stain, sometimes peritumoral inflammation and reactive stromal fibrosis obscures the tumor buds. The present study aimed to assess tumor budding using cytokeratin 20 immunohistochemistry in colorectal cancers. Methods: This is a cross sectional study which included 30 cases of colorectal carcinomas. cytokeratin 20 stained slides of colorectal carcinoma were assesed for tumor budding using International Tumor Budding Consensus Conference (ITBCC) 2016 consensus criteria and compared with AJCC cancer stage. Results: Demographic analysis showed peak incidence of colorectal cancer in the age group of 55-64 years (33.3%) and male: female ratio of 1.14:1. Majority of the tumors with score 1(23.3%) showed stage I. While tumors with score 2 had similar incidence of stage I (16.6%) and II (16.6%) and lesser incidence of stage III (3.33%). Most of the tumors with score 3 tumor budding had stage III tumors (26.67%). The p value is < 0.0001, which is statistically significant. Tumor budding signifies the biological and molecular phenomenon of epithelial-mesenchymal transition in the tumor microenvironment. Loss of E-cadherin, alterations in transcription factors including SNAIL, ZEB, TWIST etc and switching of CMS2 to CMS4 are some of the recorded molecular profiles responsible for tumor budding. Conclusion: This study concludes that the tumor stage increases with tumor budding and thus is a reliable marker in predicting the prognosis. This study also states that immunohistochemical study gives objective scoring of tumor buds in colorectal cancers. Keywords: tumor budding; colorectal cancer; cytokeratin 20; prognostic marker
Investigating the Effectiveness of the System for Training Bachelor Teachers in Health Promotion
Authors: Deikova T.N. , Mishina E.G.
Published: December 2023

A healthy nation is the main foundation and the main strategic resource of the economy and security of the Russian Federation, therefore the relevance of the phenomenon of health-saving continues to persist to the present time. The purpose of this work was to diagnose the formation of the main components of the personality of the health-preserving type student and to develop pedagogical technologies aimed at its formation. The study involved fourth-year students of all fields of education (N=199), the age of the respondents was 20 - 22 years old, of whom 79.22% (158) were female. A diagnosis of the formation of cognitive, motivational-value and activity components in the personality structure of a student of the health-saving type was carried out in the work with the help questionnaires using the method of A.R. Kamaleeva and N.V. Novozhilova, S.G. Dobrotvorskaya, the “Attitude to Health” questionnaire proposed by R.A. Berezovskaya, and also used the solutions to pedagogical cases we developed. To check statistically significant deviations in groups of students belonging to different faculties, we used analysis of variance. The data obtained during the study allowed us to conclude that the system of teacher training in the field of health-saving for the future teacher, who is both an object and a subject of health-saving activities, is not sufficiently effective. In the personality structure of the health-saving type, the activity component is the least developed, with a high level of formation of the cognitive and an average level of formation of the motivational and value components. The work puts forward a hypothesis that the pilot project developed by the department and practically implemented in the educational process - the “Health-Saving_and_I” educational guide, will contribute to the formation of the personality of a health-saving type of student. The results obtained are intermediate. To monitor the effectiveness of the guide introduced into the educational process, a second diagnosis of the formation of the personality components of a student of the health-saving type is planned after studying the disciplines of the health-saving module by students of the 2022 enrollment