bluuebunny/crossref_metadata_2025 huggingface dataset:
Age differences of patients treated with wearable cardioverter defibrillator: Data from a multicentre registry
Authors: El‐Battrawy Ibrahim , Tenbrink David , Kovacs Boldizsar , Dreher Tobias C. , Blockhaus Christian , Klein Norbert , Shin Dong‐In , Hijazi Mido , Rosenkaimer Stephanie , Beiert Thomas , Abumayyaleh Mohammad , Saguner Ardan Muammer , Kowitz Jacqueline , Erath Julia W. , Duru Firat , Mügge Andreas , Aweimer Assem , Akin Ibrahim
Published: February 2023

Background

Wearable cardioverter defibrillators (WCD) are used as a ‘bridging’ technology in patients, who are temporarily at high risk for sudden cardiac death (SCD). Several factors should be taken into consideration, for example patient selection, compliance and optimal drug treatment, when WCD is prescribed. We aimed to present real‐world data from seven centres from Germany and Switzerland according to age differences regarding the outcome, prognosis, WCD data and compliance.

Materials and Methods

Between 04/2012 and 03/2021, 1105 patients were included in this registry. Outcome data according to age differences (old ≥45 years compared to young <45 years) were analysed. At young age, WCDs were more often prescribed due to congenital heart disease and myocarditis. On the other hand, ischaemic cardiomyopathy (ICM) was more present in older patients. Wear days of WCD were similar between both groups (p = .115). In addition, during the WCD use, documented arrhythmic life‐threatening events were comparable [sustained ventricular tachycardia: 5.8% vs. 7.7%, ventricular fibrillation (VF) .5% vs. .6%] and consequently the rate of appropriate shocks was similar between both groups. Left ventricular ejection fraction improvement was documented over follow‐up with a better improvement in younger patients as compared to older patients (77% vs. 63%, p = .002). In addition, at baseline, the rate of atrial fibrillation was significantly higher in the older age group (23% vs. 8%; p = .001). The rate of permanent cardiac implantable electronic device implantation (CiED) was lower in the younger group (25% vs. 36%, p = .05). The compliance rate defined as wearing WCD at least 20 h per day was significantly lower in young patients compared to old patients (68.9% vs. 80.9%, p < .001). During the follow‐up, no significant difference regarding all‐cause mortality or arrhythmic death was documented in both groups. A low compliance rate of wearing WCD is predicted by young patients and patients suffering from non‐ischaemic cardiomyopathies.

Conclusion

Although the compliance rate in different age groups is high, the average wear hours tended to be lower in young patients compared to older patients. The clinical events were similar in younger patients compared to older patients.
Mechanisms of mindfulness in patients with migraine: Results of a qualitative study
Authors: Estave Paige M. , Margol Caitlyn , Beeghly Summerlyn , Anderson Reid , Shakir Mariam , Coffield Alexandra , Byrnes Julia , O'Connell Nathaniel , Seng Elizabeth , Gardiner Paula , Wells Rebecca Erwin
Published: February 2023

Objective

To understand the mechanisms of mindfulness' impact on migraine.

Background

Promising mindfulness research demonstrates potential benefit in migraine, but no data‐driven model exists from the lived experiences of patients that explains the mechanisms of mindfulness in migraine.

Methods

Semi‐structured qualitative interviews were conducted with adults with migraine who participated in two mindfulness‐based stress reduction (MBSR) clinical trials (n = 43). Interviews were audio‐recorded, transcribed, and summarized into a framework matrix with development of a master codebook. Constructivist grounded theory approach was used to identify themes/subthemes.

Results

Participants who learned mindfulness techniques through MBSR experienced altered pain perception, altered response to migraine attacks and disease, increased awareness of external and internal experiences, improved overall well‐being, and group benefits. Mindfulness resulted in earlier stress‐body awareness and increased interoceptive awareness resulting in earlier attack recognition, leading to earlier and more effective management. Interictal factors of self‐blame, guilt, and stigma decreased while migraine acceptance, hope, empowerment, self‐efficacy, and self‐compassion increased. Improved emotion regulation resulted in decreased fear of migraine, pain catastrophizing, anticipatory anxiety, and pain reactivity. Although taught as prevention, mindfulness was used both acutely and prophylactically. We created a conceptual model hypothesizing that MBSR skills led to an infusion of mindfulness in daily life, resulting in altered pain perception and experience, ultimately leading to improvement in overall well‐being, which may positively feed back to the infusion of mindfulness in daily life. The therapeutic benefit of learning mindfulness in a group setting may moderate these effects.

Conclusions

This study identified several new potential mechanisms of mindfulness' effect on migraine. After learning MBSR skills, participants reported altered pain and migraine perception and experiences. Increased stress‐body and interoceptive awareness resulted in earlier migraine awareness and treatment. Mindfulness may target important interictal factors that affect disease burden such as fear of migraine, pain catastrophizing, and anticipatory anxiety. This is the first data‐driven study to help elucidate the mechanisms of mindfulness on migraine from patient voices and can help direct future research endeavors.
BirdNET: applications, performance, pitfalls and future opportunities
Authors: Pérez‐Granados Cristian
Published: February 2023

Automated recognition software is paramount for effective passive acoustic monitoring. BirdNET is a free and recently developed bird sound recognizer. I performed a literature review to evaluate the current applications and performance of BirdNET, which is growing in popularity but has been subject to few assessments, and to provide recommendations for future studies using BirdNET. Prior research has employed BirdNET for a wide range of purposes but few studies have linked BirdNET detections to ecological processes or real‐world monitoring schemes. Among evaluated studies, average precision (% detections correctly identified) usually ranged around 72–85%, and recall rate (% target species vocalizations detected) ranged around 33–84%. Some studies did not assess BirdNET performance, which hampers the interpretation of the ecological results and may provide poorly informed decisions. Recommendations on how to evaluate BirdNET efficiency are provided. The impact of the confidence score threshold, a user‐selected parameter as the minimum score for detections reported, on BirdNET output although variable among species is consistent. The use of high confidence score thresholds increases the percentage of detections correctly classified but lowers the proportion of calls and bird species detected. The selection of an optimal score may depend on the priorities of the user and research goals. BirdNET is a great tool for automated bird monitoring but it should be used with caution due to inherent challenges for automated bird identification. The continued refinement of BirdNET suggests further improvements in the coming years.
Ferruginous Hawk movements respond predictably to intra‐annual variation but unexpectedly to anthropogenic habitats
Authors: Isted Georgia H. , Thomas Robert J. , Warner Kevin S. , Stuber Matthew J. , Ellsworth Ethan , Katzner Todd E.
Published: February 2023

Birds exhibit flexible movement responses to environmental variation across the annual cycle, and those responses can provide insight into potential impacts that environmental changes may have on these species. To understand year‐round variation in space use by Ferruginous Hawks Buteo regalis, we tracked 12 birds breeding in southwestern Idaho, USA, using GPS telemetry collected over 207 bird‐months. Home‐range sizes of territorial adult hawks showed strong intra‐annual variation, being smallest from April to June and largest from July to October. In contrast, juvenile birds (< 2 years old) did not appear to hold territories and showed no detectable intra‐annual variation in ranging behaviour. Association with land‐cover types by territorial birds varied between breeding and non‐breeding months and was linked to home‐range size. Home‐range sizes of non‐territorial birds were larger than those of territorial birds, and that size did not vary across the year. Association with anthropogenic habitats (irrigated cropland habitats that can provide high rodent densities and increased foraging opportunities) was negatively associated with home‐range size in months of the non‐breeding season. Unexpectedly, the opposite was true in the months of the breeding season, such that use of croplands resulted in larger home‐ranges. Patterns in home‐range size were probably linked to intrinsic factors such as the timing of breeding and migratory behaviour, and to extrinsic factors such as prey availability associated with specific land‐cover types. These results have implications for our understanding of the response of Ferruginous Hawks and other similar species to predicted changes in land cover, and they suggest unexpected relationships between human activity and wildlife behaviour. Furthermore, because the birds we tracked used a large portion of western North America, they are probably relevant far beyond the small area where these individuals were trapped.
Competitive adsorption of sodium caseinate or ovalbumin by Tween 80 impact the mechanical and microstructural properties of emulsified surimi gel systems
Authors: Yu Jiao , Xiao Hong , Xue Yong , Xue Changhu
Published: February 2023

This study first explored the competitive displacement of sodium caseinate (SC) and ovalbumin (OVA) by Tween 80 (TW) on the mechanical and microstructural properties of emulsified surimi systems. The interfacial tension of TW (8.02 ± 0.58 mN m−1) was significantly lower than that of SC (10.45 ± 0.62 mN m−1) and OVA (11.78 ± 0.69 mN m−1), and TW's addition significantly decreased the interfacial protein concentration in SC emulsion from 2.04 ± 0.18 to 1.31 ± 0.28 mg m−2 and OVA emulsion from 3.53 ± 0.04 to 2.51 ± 0.12 mg m−2 respectively (P < 0.05). The SC‐ and OVA‐emulsified gels exhibited higher hardness, adhesiveness, chewiness, gel strength, equilibrium stress, recovery rate and quality factor (Q) than TW/SC‐ or TW/OVA‐emulsified gels. Emulsion droplets are embedded in the gel matrix and evenly distributed in SC‐, OVA‐ and SC/OVA‐emulsified gel. However, in TW‐, TW/SC‐ and TW/OVA‐emulsified gel, local phase separation occurs between aggregated protein particles and oil droplets, resulting in highly heterogeneous structures. This study provides a valuable reference for utilising compound emulsifiers in the surimi industry.
Effect of in‐package cold plasma treatments on the quality of minimally processed apples
Authors: Denoya Gabriela Inés , Polenta Gustavo Alberto , Apóstolo Nancy Mariel , Cejas Ezequiel , Fina Brenda , Chamorro Juan Camilo , Ferreyra Matías , Prevosto Leandro , Vaudagna Sergio Ramón
Published: February 2023

Cold plasma technology is being increasingly used for food preservation and, incipiently, for minimal processing of fruit. Therefore, the objective of this work was to study the effect of in‐package cold plasma (generated in atmospheric‐pressure air by a low‐frequency −50 Hz‐dielectric barrier discharge operating at 30 kV) on the quality of minimally processed apples during refrigerated storage. Apple slices were subjected to the different treatments following a completely randomised design with a 3 × 3 factorial arrangement. The independent variables were the exposure time (0, 1 and 3 min) and the storage times (1, 4 and 7 days). Cold plasma treatments preserved the quality of the fruit, maintaining the tissue structure. Plasma treatment applied for 1 min rendered apple slices with the highest antioxidant content but only at day 1. Even though polyphenoloxidase activity was reduced by the treatment, it was not sufficient to stabilise the antioxidant content during storage.
Effect of ultrasonication on physicochemical, amino‐acids, sugar profile, antioxidant, pasting, and dynamic rheological properties of malted mung beans and lentils
Authors: Banura Sidhant , Singh Narpinder
Published: February 2023

This study was carried out to understand the effect of ultrasonication on different parameters of malted mung bean and lentils where ultrasonication was given for 10, 15, and 20 min, respectively to all the samples and germinated for 18 h in control conditions. These ultrasonicated malted mung beans and lentils were evaluated for physicochemical properties (protein, ash, sugars, amino acids), functional properties (water absorption, oil absorption, and foaming capacity), pasting properties, and dynamic rheology. The nutritional profile for malted mung beans and lentils improved upon ultrasonication. Protein content increased up to 21.4% and GABA up to 132% for different mung bean and lentil varieties. The pasting properties and dynamic rheology changed significantly upon treatment. Ultrasonication is a very novel non‐thermal and cost‐effective technique to improve germination rate by enhancing soaking, thus improving the nutritional profile.
Band gap and oxygen vacancy engineering of honeycomb‐like CuFe2O4 spinels toward enhanced high infrared emissivity
Authors: Cui Kai , Sun Minghui , Gong Tianyu , Xu Jiali , Hou Linrui , Yuan Changzhou
Published: February 2023

Recently, copper ferrites have acquired widespread attraction in high infrared radiation fields owing to their remarkable cost efficiency. However, to achieve broader applications under various operating conditions, it is essential to further improve the infrared emissivity, particularly at high temperatures. Herein, the Ni‐doped CuFe2O4 (NCFO) honeycomb‐like frameworks, which are constructed with single‐crystal nano‐subunits, are successfully fabricated via the scalable sol–gel avenue. The unique porous honeycomb framework endows NCFO with enhanced infrared absorption and relieves the stress between coatings and substrates meanwhile. With both band gap and oxygen vacancy (OV) engineering of CuFe2O4 itself via smart Ni doping, a maximum lattice strain, the richest OVs, and the narrowest band gap (∼1.63 eV) are simultaneously achieved for the CuFe2O4 with 15% Ni doping (denoted as CNFO‐15). Benefiting from the synergy of these external and intrinsic contributions, the CNFO‐15 possesses an ultrahigh infrared emissivity (∼0.975) in the wavelength range of 3–5 µm at a test temperature of 800°C. Moreover, the CNFO‐15‐based coating displays superior infrared radiation performance with outstanding high‐temperature resistance. More meaningfully, the constructive design here will provide a distinctive perspective for future large‐scale fabrication of advanced high‐infrared‐emissivity coatings.
Firm‐Level Climate Change Exposure
Authors: SAUTNER ZACHARIAS , VAN LENT LAURENCE , VILKOV GRIGORY , ZHANG RUISHEN
Published: February 2023

We develop a method that identifies the attention paid by earnings call participants to firms' climate change exposures. The method adapts a machine learning keyword discovery algorithm and captures exposures related to opportunity, physical, and regulatory shocks associated with climate change. The measures are available for more than 10,000 firms from 34 countries between 2002 and 2020. We show that the measures are useful in predicting important real outcomes related to the net‐zero transition, in particular, job creation in disruptive green technologies and green patenting, and that they contain information that is priced in options and equity markets.
Prognostic significance of the neural invasion in oral squamous cell carcinoma
Authors: da Dolens Eder Silva , de Morais Everton Freitas , Paranaíba Lívia Máris Ribeiro , Rangel Ana Lúcia Carrinho Ayroza , Almangush Alhadi , Salo Tuula , Brennan Peter A. , Coletta Ricardo D.
Published: February 2023

Background

Although nerve involvement can predict recurrence and prognosis in oral squamous cell carcinomas, there still have controversies and limitations regarding the standardization for its detection. In this study, we explore the impact of neural invasion in oral squamous cell carcinomas prognosis, comparing intraneural invasion (tumor cells inside nerve structure) and perineural invasion (cells involving the nerve, but not invading its sheath).

Methods

Surgical slides stained with hematoxylin and eosin from 235 patients with oral squamous cell carcinomas were carefully verified for the presence of intraneural invasion and perineural invasion. The location in the tumor (intratumoral vs. peritumoral) and number of foci (unifocal or multifocal) were also explored. Survival analyses for cancer‐specific survival and disease‐free survival were performed with Cox proportional model.

Results

Neural invasion was identified in 74 cases, 64.9% displayed intraneural invasion and 35.1% displayed perineural invasion. Univariate analysis revealed a significantly poorer cancer‐specific survival, but not disease‐free survival, in patients with intraneural invasion, in contrast to cases with perineural invasion that did not achieve significant association with both cancer‐specific survival and disease‐free survival. Further analyses revealed that the location in the tumor and number of foci had little impact on discriminatory ability of intraneural invasion. Multivariate analysis confirmed that intraneural invasion is significantly and independently associated with poor cancer‐specific survival (hazard ratio: 2.50, 95% CI: 1.31–3.79, p = 0.003).

Conclusion

This study provides evidence that intraneural invasion, but not perineural invasion, is a relevant predictor of survival in patients with oral squamous cell carcinomas, suggesting that its association with other clinical and pathological prognostic factors should be consider in determining the optimal treatment protocol and prognosis of these patients.
“Changing” one's mind: Historical epistemology as normative psychology
Authors: Simons Massimiliano
Published: February 2023

This article argues that historical epistemology offers the history of philosophy and science more than a mere tool to write the history of concepts. It does this, first of all, by rereading historical epistemology through Michel Foucault's “techniques of the self.” Second, it turns to the work of Léon Brunschvicg and Gaston Bachelard. In their work we see a proposal for what the subjectivity of scientists and philosophers should be. The article thus argues that their work is driven by a normative psychology: a set of prescriptions for which mental constitution a scholarly self has to have. In the Conclusion, it returns to existing analyses of “open‐mindedness” as a virtue and explores in what way these cases challenge these analyses, as well as to what extent Foucault's “techniques of the self” can be applied to other cases in the history of French philosophy.
The memory politics of Cursed Soldiers, antisemitism and racialisation
Authors: Jaskulowski Krzysztof , Majewski Piotr
Published: February 2023

This paper examines the relationship between racism and the memory politics of the anti‐communist underground in Poland. It explores a covert antisemitism behind the conservative nationalist hegemonic project of transforming the anti‐communist underground into the ideologically charged symbol of the Cursed Soldiers. It demonstrates that under the conditions of the condemnation of antisemitism, the symbolism of the Cursed Soldiers has become a covert way of expressing anti‐Jewish prejudice in hegemonic memory politics. The paper argues that this covert antisemitism must be seen in the broader context of historical racialised antisemitism and racialised structures of Polish national identity. The paper challenges the notion of Poland as a country free from racism, by unpacking the role of racialisation in the dominant understanding of Polishness. It demonstrates how the memory politics of the Cursed Soldiers fit into the racialised logic of the dominant ideology of Polish national identity.
High frequency of memory stem cells with a distinct gene signature in HIV patients with treatment interruption
Authors: Sachdeva Meenakshi , Sharma Aman , Arora Sunil K.
Published: February 2023

Reservoirs of HIV remain a major obstacle to the complete eradication of virus despite regular anti‐retroviral therapy (ART). Memory stem cells (Tscm), one of the major reservoirs, are relatively less studied owing to their presence in lower numbers and inaccessible anatomical locations. We have evaluated the molecular characteristics of Tscms in patients with ART interruption (n = 15) versus patients on uninterrupted ART (n = 12) using flow cytometry. RNA sequencing was done in the sorted Tscms to study the differential gene expression. Patients with ART interruption had significantly lower baseline CD4+T‐cell counts and high viral loads as compared to patients on ART. The former group had significantly higher frequency of CD4+ and CD8+Tscms with a higher expression of PD‐1 on CD8+Tscms. The transcriptome profile of Tscm was significantly different among the patient groups. The main pathways were cellular and metabolic pathways, cellular development pathways, cell differentiation and negative regulation of cellular migratory pathways. An increased yet dysfunctional CD8+ memory stem cells describe HIV‐1‐infected patients with break‐in ART and a distinct transcriptional signature of CD4+ Tscm as compared to those of patients on ART. A more detailed understanding of the biology and dynamics of Tscm in future studies is warranted. Strategies to improve the functionality of the CD8+ Tscm will help these patients to tackle the outburst of viral replication that occurs after the cessation of therapy.
Black feminist theory in maternal health research: A review of concepts and future directions
Authors: Brantley Mia
Published: February 2023

Black maternal health and well‐being has become a necessary focal point for health researchers due to higher rates of maternal mortality and morbidity for Black women. However, what is often absent from this scholarship within medical sociology is Black Feminist Theory as a framework for understanding Black women's health and well‐being. Drawing on Black feminist and maternal health scholarship, I argue that integrating Black feminist approaches in maternal health research expands our understandings of what processes and mechanisms are impacting the health and well‐being of Black mothers, while also highlighting the importance of maternal health research that solely centers Black women. Specifically, I focus on three concepts of Black Feminist Theory as it relates to Black maternal health research: (1) examining Black women's standpoint as credible, (2) acknowledging the historical context of multiple systems of oppression against Black women, and (3) incorporating a perspective that acknowledges both disadvantages, as well as empowerment, in the lives of Black women. I end this review with a discussion of future directions for sociological research in maternal health, including the importance of acknowledging how Black mothers are both impacted by, and resisting, social structures that may add nuance to our current understandings of Black maternal health and well‐being.
Developing the social identity theory of leadership: Leader agency in leader group prototypicality
Authors: van Knippenberg Daan
Published: February 2023

The social identity theory of leadership is a unique perspective in leadership research in capturing how responses to leadership are informed by how the leader is perceived through the lens of the group identity shared by leaders and followers. I review the theory in broad strokes to make the case that a particularly valuable future development of the theory is to complement the theory's emphasis on group member (follower) perceptions of leader group prototypicality, the extent to which the leader is perceived to embody the group identity, with theory and evidence speaking to leader agency in influencing such perceptions.
Retrospective evaluation of intravenous catheterization in client‐owned lizards at a veterinary teaching hospital: 21 cases (2018–2021)
Authors: Liles Marina , Brandão João , Di Girolamo Nicola
Published: February 2023

Objective

To assess the prevalence of lizards presenting to a university teaching hospital that had an IV catheter placed, the catheterization sites used, and complications arising with the placement of the catheter both in the short and long term.

Design

Retrospective study.

Setting

University teaching hospital.

Animals

Twenty‐one lizards, including inland bearded dragons (Pogona vitticeps; 15/21), green iguanas (Iguana iguana; 4/21), and veiled chameleons (Chamaeleo calyptratus; 2/21).

Interventions

None.

Measurements and Main Results

Of 129 lizard consultations performed between September 27, 2018 and September 27, 2021, 21 catheters were placed, resulting in an overall prevalence of 16.3%. Reasons for catheter placement included hospitalization for fluid therapy (10/21 [47.6%]), anesthesia or surgery ± hospitalization (7/21 [33.3%]), computed tomography scan with contrast (2/21 [9.5%]), euthanasia only (1/21 [4.8%]), and CPR only (1/21 [4.8%]). All catheters were placed in the ventral coccygeal vein via a ventral approach. Sedation was used in 6 of 21 (28.6%) of the catheters placed. Seven of the catheters (35%) were used for administration of fluids only, 4 (20%) were used for administering drugs/medications only, and 9 (45%) catheters administered both fluids and drugs/medications. No complications were noticed in any of the lizards that had catheters placed, both in the short and long term.

Conclusions

Based on the retrospective evaluation of medical records at a veterinary teaching hospital, IV catheter placement in lizards is feasible, including in conscious animals, with roughly 1 consultation out of 6 resulting in a catheter placed. The most frequent reason for catheter placement was for administration of fluids.
Concurrent measurement of serum and radiomic biomarkers in the clinical investigation of equine musculoskeletal injuries: A prospective pilot study
Authors: Tually Peter , Currie Geoff , Blache Dominique , Meadows Jack , Gray Chloe , Hemmings Lisa , O'Callaghan Paul , Murphy David
Published: February 2023

The prevention of musculoskeletal injuries and their related welfare and economic impacts represent an immediate priority for the horse racing industry. This prospective pilot study aimed to evaluate a method to quantitatively analyze scintigraphic features of specific anatomical regions of the horse's appendicular skeleton in combination with secondary measures of musculoskeletal metabolism in blood. Twelve horses referred for scintigraphic assessment of lameness were enrolled. Blood samples were collected immediately prior to the administration of radiotracer. Serum concentrations associated with bone turnover were determined for the following biomarkers: C‐terminal telopeptides of type I collagen, proteoglycans and sulfated glycosaminoglycans, collagen type II, osteocalcin, and procollagen II C‐terminal propeptide. Scintigraphic images underwent radiomic analysis of discrete regions of the distal limbs and these data were correlated to bone turnover markers. Three lame horses demonstrated asymmetrical radiomic abnormalities. The concentration of osteocalcin in the lame horses was significantly higher when compared to the control group, while no significant changes were observed for the other screened serum biomarkers. Findings from the current study provided evidence that radiomic analysis of equine scintigraphy is feasible. This method has the potential to interrogate which serum markers are associated with musculoskeletal injuries.
DETECTION AND CLASSIFICATION OF PLANT LEAF DISEASES USING DIGTAL IMAGE PROCESSING METHODS: A REVIEW
Authors: Mohammed Lele , Yusoff Yusliza
Published: February 2023

Prediction and classification of plant leaf illnesses by farmers using conventional approaches can be unexciting and erroneous. Problems may occur while trying to predict the sort of illnesses manually. Inability to detect diseases of plants promptly could lead to the destruction of crop plants and this can cause serious decline in the yield. Losses can be prevented and yield be maximized when farmers adopt computerized image processing approaches in their farms. Numerous techniques have been proposed and used in the prediction of diseases of crop plants based on the images of the infected leaves. Researchers have in the past achieved a lot in the aspect of plant illnesses identification by exploring several techniques and models. However, improvement needs to be provided on account of reviews, new advancements and discussions. Deploying technology can greatly enhance crop production across the globe.  Different approaches and models can be trained with huge data to identify new improved methods for uncovering diseases of plants to tackle problem of low yield. Previous works have determined the robustness of various image processing techniques such as; K-means clustering, Naive Bayes, Feed forward neutral network (FFNN), Support Vector Machine (SVM), K-nearest neighbor (KNN) classifier, Fuzzy logic, Genetic Algorithm (GA), Artificial Neural Network (ANN), Convolutional Neural Network (CNN) etc. This paper provides a critical review and results of different types of approaches and methods used previously to detect and classify various types of plant leaf illnesses using image processing approaches.
OPTIMUM DESIGN OF TUNED MASS DAMPER PARAMETERS TO REDUCE SEISMIC RESPONSE ON STRUCTURE USING GENETIC ALGORITHM
Authors: Suryadi Dedi , Prasetya Argian , Daratha Novalio , Agustian Indra
Published: February 2023

A tuned mass damper (TMD) is a system to improve structural performance in reducing vibration response under seismic loads. This study optimizes TMD parameters using a genetic algorithm. In this study, the structure is modeled as a spring-mass system to obtain mathematical equations. Then, those equations are used to estimate vibration due to seismic loads. A genetic algorithm is used to find optimum parameters which correspond to minimum vibrations. The simulation result shows that the genetic algorithm can find values of parameters such as the ratio of mass, stiffness, and damping values ​​which reduces vibrations on the structure. Based on the tests, it is found that the best combination of genetic algorithm parameters to produce the most optimal fitness value is population size 30, generation size 800, crossover probability 0.5, and mutation probability 0.5. Applying the genetic algorithm shows that the optimal parameter ratio values of TMD ​​to reduce the vibration response are 10% mass, 10% stiffness, and 1% damping of mass, stiffness, and damping in the structure. The result of the vibration response analysis shows that the maximum amplitude value of the main structure without TMD is 0.24259 m reduced to 0.034385 m with the addition of TMD. This shows that the TMD successfully reduces vibrations in the main structure with a percentage of 85.94%. Where the TMD manages to dissipate the energy that should only be received by the structure to the TMD itself.
EXPERIMENTAL STUDY ON PRESSURIZED ADSORPTION OF CARBON DIOXIDE AND METHANE FROM COMPLEX GAS MIXTURE OF BIOGAS IN ZEOLITE 13X
Authors: Al Kindi Hablinur , Fadillah Achmad Kemal , Yuliana Iyan , Hartulistiyoso Edy , Salundik Salundik , Tambunan Armansyah Halomoan
Published: February 2023

The majority of research on biogas adsorption does not use biogas gas but by mixing CO2 and CH4 gas or (binary gas) or with additional other gases, such as N2 or H2S. In real application, the adsorption method of biogas purification is conducted by using its complex mixture of biogas to obtain the purer methane gas. Accordingly, in case of biogas purification, adsorption capacity of the adsorbent towards both CH4 and CO2 gases from a complex gas mixture of biogas is indispensable to be studied thoroughly for improving the existing purification method, such as the pressure swing adsorption (PSA) method. The objective of this experiment is to compare the adsorption of carbon-dioxide and methane from complex mixture of biogas by Zeolite 13X under pressurized condition using experimental data. The experiment was conducted using a specially designed experimental setup, and the data obtained was evaluated and analyzed using the Freundlich Isotherm Model. The results show that experimental study on the adsorption of CO2 and CH4 gas from complex mixture of biogas in Zeolite 13X was distinguishable by their values of Freundlich coefficient. CO2 and CH4 gas adsorption in zeolite vary directly with pressure raised to the power 1/n, where its value for CH4 adsorption was higher than CO2. However, within the range of applicable pressure, the equilibrium adsorption of CO2 in Zeolite 13X was still higher than that of CH4.
Pandemik di Timur Tengah Dalam Karya Kesusasteraan Arab: Satu Tinjauan Awal (Pandemics in the Middle East in Arabic Literary Works: A Preliminary Review)
Authors: Zohkarnain Nur Asyiqin , Lubis Firuz-Akhtar
Published: February 2023

History has proven the existence of global pandemics since centuries ago that profoundly impacted society. The situation of society during the pandemic can be seen through readings of Arabic literature works which play very important roles in getting the picture of Middle East society. The purpose of this study is to identify preliminary review related to pandemics in the Middle East which are recorded in Arabic literary works. This study uses qualitative method by analyzing the content of corpora based on thematic method. Based on this preliminary review, several new themes have been developed including the theme of infectious diseases in the Middle East such as cholera and black death. Aspects discussed including the location of the pandemic, the community's situation against the pandemic, the impact, and how to deal with the pandemic. As a result of this literature review, it is found that in discussion about the pandemic, Arabic literary works give special emphasis on the sociology of society, health, and ecosystem of a country. Therefore, it is hoped that more Arabic literary masterpieces can be translated due to it importance and benefit for future research regarding pandemic
Current status of structural studies of proteins originating from Arachnida
Authors: Kader Safaa , Arriaza Ricardo H. , Khatri Kriti , O’Malley Andrea , Grbic Vojislava , Grbic Miodrag , Chruszcz Maksymilian
Published: February 2023

Arthropods from class Arachnida constitute a large and diverse group with over 100,000 described species, and they are sources of many proteins that have a direct impact on human health. Despite the importance of Arachnida, few proteins originating from these organisms have been characterized in terms of their structure. Here we present a detailed analysis of Arachnida proteins that have their experimental structures determined and deposited to the Protein Data Bank (PDB). Our results indicate that proteins represented in the PDB are derived from a small number of Arachnida families, and two-thirds of Arachnida proteins with experimental structures determined are derived from organisms belonging to Buthidae, Ixodidae, and Theraphosidae families. Moreover, 90% of the deposits come from just a dozen of Arachnida families, and almost half of the deposits represent proteins originating from only fifteen different species. In summary, our analysis shows that the structural analysis of proteins originating from Arachnida is not only limited to a small number of the source species, but also proteins from this group of animals are not extensively studied. However, the interest in Arachnida proteins seems to be increasing, which is reflected by a significant increase in the related PDB deposits during the last ten years.
Species boundaries among extremely diverse and sexually dimorphic Arrenurus water mites (Acariformes: Hydrachnidia: Arrenuridae)
Authors: Więcek Mariusz , Broda Łukasz , Proctor Heather , Dabert Mirosława , Smith Bruce P. , Dabert Jacek
Published: February 2023

Arrenurus (Arrenuridae) is the most species-rich genus of mites with about 1000 named species that inhabit standing, and to a lesser extent, running water habitats around the world. To date, distinguishing species of Arrenurus has been based on male reproductive morphology. Here, we use morphological and molecular approaches to examine species boundaries among 42 named species of Arrenurus, including four named species that have colour variants (red and green A. americanus, and red and blue A. intermedius, A. manubriator and A. apetiolatus), and two unnamed morphospecies. In this study, we examine male genital structures with the use of SEM techniques, and apply mitochondrial (COI barcode region) and nuclear (28S rRNA) gene fragments to test whether male morphology reflects species boundaries in Arrenurus assessed by molecular analyses. Our results reveal that male reproductive morphology parallels species boundaries as judged by molecular data. We discuss the cases of genetically poorly diversified, yet morphologically clearly defined named species. Moreover, we show that based on the species we examined, colour morphs within otherwise morphologically similar specimens represent within-species variation and, in the absence of other diagnostic traits, colour itself can be misleading in distinguishing species. Our outcomes on molecular taxonomy of Arrenurus provide a background for testing hypotheses about speciation rate in water mites.
Two similar species of genus Metabelba Grandjean, 1936 (Acari, Oribatida, Damaeidae) from Crimea and Caucasus
Authors: Kolesnikov Vasiliy B. , Murvanidze Maka , Marchenko Irina I.
Published: February 2023

Metabelba (Pateribelba) flagelliseta Bulanova-Zachvatkina, 1965 is redescribed based on the newly sampled material from Crimea and investigation of the specimens from the collection of Bulanova-Zachvatkina. Metabelba (Metabelba) pseudoflagelliseta Kolesnikov & Murvanidze sp. nov. is described from Caucasus, Georgia. Both species have similar morphology, characterized by flagellated notogastral setae and same set of tubercles, but differ by presence or absence of apophysis P and shape of the dorsal seta on femora III–IV. Considering the importance of these morphological characters we assign these species to different subgenera.
Notes on the family Oripodidae (Acari, Oribatida) in South Africa and description of a new species of Cryptoribatula Jacot
Authors: Hugo-Coetzee Elizabeth A.
Published: February 2023

The family Oripodidae is not well known in South Africa with only one species, Oripoda sumonyii, described and recorded. This paper reports five genera from South and describes a new species, Cryptoribatula austroafricana sp. nov., from yellow lichen on boulders on a beach. The new species differs from the other two species from the genus mainly in the number of notogastral, genital and aggential setae. The male and female of the new species differ slightly from each other. A generic diagnosis is provided as well as selected characteristics of all Oripodidae genera.
A self-powered multifunctional dressing for active infection prevention and accelerated wound healing
Authors: Barman Snigdha Roy , Chan Shuen-Wen , Kao Fu-Cheng , Ho Hsuan-Yu , Khan Imran , Pal Arnab , Huang Chih-Ching , Lin Zong-Hong
Published: February 2023

Interruption of the wound healing process due to pathogenic infection remains a major health care challenge. The existing methods for wound management require power sources that hinder their utilization outside of clinical settings. Here, a next generation of wearable self-powered wound dressing is developed, which can be activated by diverse stimuli from the patient’s body and provide on-demand treatment for both normal and infected wounds. The highly tunable dressing is composed of thermocatalytic bismuth telluride nanoplates (Bi
2
Te
3
NPs) functionalized onto carbon fiber fabric electrodes and triggered by the surrounding temperature difference to controllably generate hydrogen peroxide to effectively inhibit bacterial growth at the wound site. The integrated electrodes are connected to a wearable triboelectric nanogenerator (TENG) to provide electrical stimulation for accelerated wound closure by enhancing cellular proliferation, migration, and angiogenesis. The reported self-powered dressing holds great potential in facilitating personalized and user-friendly wound care with improved healing outcomes.
Glia turn opioids painful
Authors: Ferrarelli Leslie K.
Published: February 2023

Co-targeting glial cells may block the paradoxical increase in pain caused by repeated opioid use.
Local Regulator AcrR Regulates Persister Formation by Repression of AcrAB Efflux Pump during Exponential Growth in Aeromonas veronii
Authors: Ma Xiang , Hu Kang , Xiong Yuesheng , Li Hong , Li Juanjuan , Tang Yanqiong , Liu Zhu
Published: February 2023

Bacterial persisters refer to a small fraction of dormant variants that survive treatment with high concentrations of antibiotics. Increasing research indicates that multidrug efflux pumps play a major role in persister formation in many Gram-negative organisms.
Emergence of Carbapenemase-Producing Hypervirulent Klebsiella pneumoniae in Switzerland
Authors: Hallal Ferreira Raro Otávio , Nordmann Patrice , Dominguez Pino Manuel , Findlay Jacqueline , Poirel Laurent
Published: February 2023

Increasing occurrence of multidrug-resistant (MDR) and hypervirulent (hv)
Klebsiella pneumoniae
(MDR-hvKp) convergent clones is being observed. Those strains have the potential of causing difficult-to-treat infections in healthy adults with an increased capacity for mortality.
Repurposing Axl Kinase Inhibitors for the Treatment of Respiratory Syncytial Virus Infection
Authors: Zhang Dan , Zhao Yuanhui , You Xiaoxin , He Susu , Li Erguang
Published: February 2023

Respiratory syncytial virus (RSV) infection persists as a common pathogen of pulmonary infection in infants and in the elderly with high morbidity and mortality. However, no specific therapeutics are available.
Safety, Tolerability, and Pharmacokinetics of Anti-SARS-CoV-2 Immunoglobulin Intravenous (Human) Investigational Product (COVID-HIGIV) in Healthy Adults: a Randomized, Controlled, Double-Blinded, Phase 1 Study
Authors: Liu Sean T. H. , Mirceta Mila , Lin Grace , Anderson Deborah M. , Broomes Tarashon , Jen Alina , Abid Ashley , Reich David , Hall Christine , Aberg Judith A.
Published: February 2023

Anti-SARS-CoV-2 immunoglobulin (human) investigational product (COVID-HIGIV) is a purified immunoglobulin preparation containing SARS-CoV-2 polyclonal antibodies. This single-center clinical trial aimed to characterize the safety and pharmacokinetics of COVID-HIGIV in healthy, adult volunteers.
Application of a CRISPR Sequence-Based Method for a Large-Scale Assessment of Salmonella Serovars in Ontario Poultry Production Environments
Authors: Quinn Matthew W. , Linton Nicola F. , Leon-Velarde Carlos G. , Chen Shu
Published: February 2023

The CRISPR-SeroSeq method represents an alternative molecular tool to the traditional culture-based serotyping method that can detect multiple
Salmonella
serovars in a sample and provide rapid serovar results without the need of selective enrichment and culture isolation. The evaluation results can facilitate implementation of the method in routine
Salmonella
surveillance on poultry farms and in outbreak investigations.
Genetic, Functional, and Immunogenic Analyses of the
O
-Linked Protein Glycosylation System in Neisseria meningitidis Serogroup A ST-7 Isolates
Authors: Næss Lisbeth M. , Maugesten Ingunn S. , Caugant Dominique A. , Kassu Afework , Aseffa Abraham , Børud Bente
Published: February 2023

Bacterial meningitis is a serious global health problem, and one of the major causative organisms is
Neisseria meningitidis
. Extensive variability in protein glycan structure and antigenicity is due to phase variation of protein glycosylation genes and polymorphic gene content and function.
Clinical Evaluation of a New Molecular Test for the Detection of Organisms Causing Vaginitis and Vaginosis
Authors: Lillis Rebecca A. , Parker R. Lamar , Ackerman Ronald , Ackerman Jamie , Young Stephen , Weissfeld Alice , Trevino Ernest , Nachamkin Irving , Crane LaShonda , Brown Jacqueline , Huang Christina , Liu Xiaohong , Van Der Pol Barbara
Published: February 2023

In this prospective, observational, method comparison clinical study, the Xpert Xpress MVP test (MVP) was evaluated using both clinician-collected (CVS) and self-collected vaginal swabs (SVS) collected in a clinical setting. The study was conducted at 12 sites, including point-of-care (POC) settings, from geographically diverse locations in the United States.
Cerebral Malaria Is Regulated by Host-Mediated Changes in
Plasmodium
Gene Expression
Authors: Cimperman Clare K. , Pena Mirna , Gokcek Sohret M. , Theall Brandon P. , Patel Meha V. , Sharma Anisha , Qi ChenFeng , Sturdevant Daniel , Miller Louis H. , Collins Patrick L. , Pierce Susan K. , Akkaya Munir
Published: February 2023

Hundreds of thousands of lives are lost each year due to the brain damage caused by malaria disease. The overwhelming majority of these deaths occur in young children living in sub-Saharan Africa.
Adjunctive Integrated Stress Response Inhibition Accelerates Tuberculosis Clearance in Mice
Authors: Krug Stefanie , Prasad Pankaj , Xiao Shiqi , Lun Shichun , Ruiz-Bedoya Camilo A. , Klunk Mariah , Ordonez Alvaro A. , Jain Sanjay K. , Srikrishna Geetha , Kramnik Igor , Bishai William R.
Published: February 2023

Necrosis of lung lesions is a hallmark of tuberculosis (TB) that promotes bacterial growth, dissemination, and transmission. This process is driven by the persistent hyperactivation of the integrated stress response (ISR) pathway.
At the Crossroad of Nucleotide Dynamics and Protein Synthesis in Bacteria
Authors: Leiva Lorenzo Eugenio , Zegarra Victor , Bange Gert , Ibba Michael
Published: February 2023

Nucleotides are at the heart of the most essential biological processes in the cell, be it as key protagonists in the dogma of molecular biology or by regulating multiple metabolic pathways. The dynamic nature of nucleotides, the cross talk between them, and their constant feedback to and from the cell’s metabolic state position them as a hallmark of adaption toward environmental and growth challenges. It has become increasingly clear how the activity of RNA polymerase, the synthesis and maintenance of tRNAs, mRNA translation at all stages, and the biogenesis and assembly of ribosomes are fine-tuned by the pools of intracellular nucleotides. With all aspects composing protein synthesis involved, the ribosome emerges as the molecular hub in which many of these nucleotides encounter each other and regulate the state of the cell.
Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000
Authors: Golparian Daniel , Jacobsson Susanne , Ohnishi Makoto , Unemo Magnus
Published: February 2023

Zoliflodacin is a promising novel antimicrobial in clinical development for treatment of gonorrhea; currently, it is in a global phase 3 randomized controlled clinical trial. High activity against global
Neisseria gonorrhoeae
strains has been shown. We present the complete reference genome of the zoliflodacin-resistant strain H035, which was identified in Japan in 2000.
A Genome-Scale Metabolic Model of Marine Heterotroph Vibrio splendidus Strain 1A01
Authors: Iffland-Stettner Arion , Okano Hiroyuki , Gralka Matti , Guessous Ghita , Amarnath Kapil , Cordero Otto X. , Hwa Terence , Bonhoeffer Sebastian
Published: February 2023

A genome-scale metabolic model of
V. splendidus
1A01 was reconstructed in this work. We offer solutions to the technical problems associated with model reconstruction for a marine bacterial strain like
V. splendidus
1A01, which arise largely from the high salt concentration found in both seawater and culture media that simulate seawater.