bluuebunny/crossref_metadata_2025 huggingface dataset:
The works of prof. Zondeks about the metabolism of bromine in the body and its importance in depression and sleep
Authors: Kislev M.
Published: October 2021

Over the past months, a number of reports have been held in German medical centers. Islands (and one in Moscow, where Prof. Zondek came) and a number of brief reports of the famous German endocrinologist prof. Z o n d e k'a about the metabolism of bromine and the biological role of this halogen. Taking into account the personality of the author and the significance of the question, which, perhaps, opens a new chapter in biology and clinic, we consider it necessary now to give abstracts of these short reports by Zondek, although they are only preliminary.
Chronicle Volume 32, No. 5-6 (1932)
Authors: Team Editorial
Published: October 2021

June 5 to 30 p. The city of NKZ RSFSR convened a methodological meeting on medical education.
Importance of anatomo-topographic peculiarities for endoscopic diagnosis and treatment of Sphenoiditis
Authors: Mikhailov M. K. , Svatko L. G. , Krasnozhen V. N. , Mosikhin S. B.
Published: October 2021

The results of anatomo-topographic investigation of 100 clinoid sinuses obtained in autopsy of 50 dead persons are given. The relations of clinoid sinuses with posterior cells of ethmoidal labyrinth are found, the location of natural anastomoses of sinuses on the anterior wall is defined. The case record of the patient with sphenoiditis after endoscopic surgical intervention is given. The role of endoscopic method for diagnosis and treatment of sphenoiditis is shown.
Otosclerosis: problems of pathogenesis and conservative treatment
Authors: Kiselev A. S.
Published: October 2021

Thanks to advances in cofosurgery, a significant number of patients with otosclerotic hearing loss have improved hearing. Nevertheless, many problems of this disease continue to remain relevant at the present time. Among them, the pathogenesis of otosclerosis, as well as the mechanism of inhibition of the activity of the otosclerotic process, should be distinguished, especially in those cases when the otosclerotic rearrangement captures the cochlear region of the ear labyrinth.
Herbal medicine in the complex treatment of patients with chronic tonsillitis
Authors: Guseva L. N.
Published: October 2021

A clinical assessment of the combination of inhalation therapy with phytopreparations and agents affecting the immune system was carried out. The study included 60 patients with chronic tonsillitis aged 15 to 45 years with a disease duration of 2 to 20 years. Patients, in addition to clinical examination, underwent sowing of flora from the depths of the lacunae to detect microbes or fungi, followed by determination of sensitivity to antibiotics, and skin allergological tests with microbial allergens were performed.
Dissolution of gallstones in vitro
Authors: Zulkarneev R. A. , Polovnik V. K. , Chugunov A. N.
Published: October 2021

With the help of ultrasound and NMR tomography, the diagnosis of stones in the biliary tract has improved significantly. In this regard, the number of patients who want to get rid of stones, the existence of which they did not even suspect before the examination, is growing significantly. The low trauma of laparoscopic cholecystectomy (LCE) is captivating, and there is a danger of expanding the indications for this, already quite common operation. But the removal of the organ necessary for digestion excludes the possibility of new painful disorders.
The comparision of two diagnostic methods for detection of Helicobacter pylori in gastric mucosa
Authors: Krasin V. V. , Chasanov R. Sh. , Garifullin R. I. , Maksimov P. A. , Kiassov A. P.
Published: October 2021

The two diagnostic methods for detection of Helicobacter pylori have been tested. The first one was de-nol test, which was based on detection of the urease activity. The second one was the immunocytochemical method using the polyclonal antibodies against Helicobacter pylori. During the fibrogastroscopy of patients with gastric desease (20 persons) the small pieces of gastric mucosa were taken. The latters were used for preparation of smears and then for de-nol test. 18 patients have got the positive de-nol tests, and the analyses of two patients were negative. However, the Helicobacter pylori were detected in all cases, using the immunocytochemical staining with polyclonal antibodies against this bacterium. On the base of these results we have suggested that immunocytochemical staining of Helicobacter pylori is more informative and more precise than de-nol test.
Apparatus method in the treatment of eventration into the purulent wound
Authors: Izmailov S. G. , Garaev V. N.
Published: October 2021

The clinical use of the apparatus method in 15 patients with eventration into the purulent wound allows to obtain the best immediate and remote results comparing with the traditional method. The reliable closure of the peritoneal cavity is achieved during the junction of the wound lips. The junction of the wound li ps by stages occurs without destruction of tissue and the optimum conditions are created for the course of regenerative processes.
The effectiveness of conservative treatment of pulpitis with Dimexide and lysozyme
Authors: Musharapova S. I.
Published: October 2021

The effectiveness of conservative treatment of acute serous limited and chronic fibrous pulpitis with the use of Dimexide and lysozyme, as well as their combination, has been studied. The high therapeutic efficacy of the studied treatment options for acute serous limited pulpitis has been shown.
Worm infestations among workers (and employees) of the Kulebak Metallurgical Plant due to their general morbidity
Authors: Tumanovsky M. N.
Published: October 2021

Regarding the spread of worm infestations, their role in human pathology, there is a large literature both abroad and here, and yet practitioners take little account of this important factor in general pathology, as well as the economic and economic effect of anti-worm measures among the population and especially among the actively insured. Numerous neurotic, anaemic patients with chronic gastrointestinal tract sufferings flood our outpatient clinics; various, sometimes contradictory diagnoses are made, they are often given disability sheets, and meanwhile, in a significant percentage, these patients could maintain their ability to work with simple anthelminthological measures, and the insurance authorities would save considerable funds on this.
A one-stage, one-incision operation on the kidney, gallbladder and caecum under local anesthesia
Authors: Vishnevsky A. V.
Published: October 2021

The idea of the possibility of access from the lumbar incision to the liver, gallbladder and ducts is not new; there are numerous references to this in the literature (Fgapk, Meags, Tu ffieg, Wgight, Reboul, Trinkler, etc.). Frank, for example, even points to the benefits of a lumbar incision for surgery on the biliary tract in terms of convenience of postoperative treatment, convenience of drainage and less danger of postoperative hernias. Most recently, Hrtel) has been focusing the attention of surgeons on lumbar incisions for operations not only on retroperitoneal organs, but also for abdominal operations (spleen, pancreas, duodenum, colon, etc.). Without mentioning the whole issue here, I must say that the clinic has enough reasons for wanting to get operative access to the right kidney and gallbladder simultaneously. The first reason for this in normal conditions may be diagnostic difficulties. There are cases when the surgeon, exposing the kidney, simultaneously felt the stones in the gallbladder and was forced to continue the operation on the bile ducts from the same incision.
Etiology and pathogenesis of coxarthrosis and methods of its treatment
Authors: Akberdina D. L.
Published: October 2021

Coxarthrosis is one of the most common degenerative-dystrophic diseases of the musculoskeletal system and often leads to significant disability and even disability. The etiology and pathogenesis of coxarthrosis have not yet been clarified. The causes of this disease can be the following disorders: metabolic endocrine, static-dynamic and neurovascular.
On the origin and surgical treatment of solitary bone cysts in children
Authors: Grigoriev M. G. , Abakarov A. A.
Published: October 2021

The results of treatment of 205 children with bone cysts were traced. It was revealed that osteoblastoclastoma can be the cause of cysts only in 15.6% of cases. The position on the possible genesis of solitary bone cysts due to dysplasia of the growth zone has been substantiated. In the surgical treatment of bone cysts, the method of choice is the marginal resection of the affected bone with replacement of the defect in the "bundle of brushwood" type. With active growth of the cyst, frequent pathological fractures, segmental bone resection with replacement of the defect with a massive allograft with longitudinal cuts is indicated.
Use of gel with prostaglandin e2 in the context of programmed labors in primiparas
Authors: Popov S. P. , Gorin V. S. , Khristenko E. V.
Published: October 2021

The labor characteristics and contractile activity of the uterus resulting from programmed labors after the intracervical application of gel with prostaglandin E2 are studied. The gel with prostaglandin E2 was not used in the matched control group of patients with programmed labors. After introduction of the gel the modified Bishop scores significantly improved, the labor began in one of the patients. During introduction of the gel the hypertonus of the uterus or the pathology of the fetus heart rate is not observed. The length of the active phase and the second period of the labor is significantly shorter than in the control group. The contractile activity of the uterus is similar in both groups. The primary cervical effect of the gel is supposed.
Study of the functional state of the only uterine tube in women after the tubal pregnancy operation
Authors: Mazitova M. I. , Bogolyubova I. M. , Mazitov I. M.
Published: October 2021

The state of the second remained tube after the- tubal pregnancy operation in 16 patients is studied by kymographic tubal insufflation. Salpingectomy is performed in 14 patients and linear salpingotomy of the only uterine tube is performed in 2 patients. The other tube is removed during the first tubal pregnancy operation. It is found that in all patients the remained tubes are permeable as this takes place permeability, contractile activity and contraction rate decrease in 7 patients (in 5 patients after salpingectomy, in 2 patients after salpingotomy). Kymographic tubal insufflation is the information investigation method of the state of the remained uterine tube after the tubal pregnancy operation.
Change of peripheric blood indices in patients with inflammatory genesis sterility after manual therapy
Authors: Vorontsova G. M. , Ivanichev G. A. , Chernyshov V. V. , Sharapova О. V. , Efimova N. K.
Published: October 2021

The original treatment of women with tuboperitoneal sterility in the presence of adhesive process in the small pelvis and abdominal cavity owing to chronic inflammatory diseases of genital organs is performed by manual therapy methods. The dynamic control of peripheric blood indices reliably showed the positive dynamics of the number of lymphocytes and monocytes. Pregnancy occurred in 19,5% of the patients.
Target organs in arterial hypertension
Authors: Galyavich A. S.
Published: October 2021

One of the consequences of long-term BP increase is damage of internal organs, the so-called target organs (target organ damage, end organ damage). These include heart, brain, kidneys, vessels. Heart damage in arterial hypertension may be manifested by left ventricular hypertrophy, angina pectoris, myocardial infarction, chronic heart failure and sudden death, brain damage - by thrombosis and hemorrhages, hypertensive encephalopathy and cerebral lacunae, kidneys - microalbuminuria, proteinuria, chronic renal failure, vascular involvement - lesions of retinal vessels, carotid arteries, aorta (aneurysm).
Stages of the formation of clinical anatomy in Russia
Authors: Ibatullin I. A.
Published: October 2021

The history of clinical anatomy is quite complex. The progression of any fundamental discipline, and anatomy in particular, is reflected primarily in its content, which is put into concrete form. Born during the Renaissance, anatomy predetermined the success of medicine. The use of the deductive method in the practice of medicine led to the creation of descriptive anatomy, and of inductive anatomy to surgical anatomy with the condition that it must be taught to surgeons.
Clinical value of melatonin in the development of central mechanism disorders of reproductive function regulation
Authors: Fattakhova F. A. , Gilyazutdinova Z. Sh. , Mikhailov M. K.
Published: October 2021

The excretion of melatonin in central mechanism disorders of reproductive function regulation is studied. It is stated that thyroid gland calcification is a physiological process and calcification process inhibition is a manifestation of hormonal homeostasis disorder in patients with neuroendocrinic pathology. The treatment of patients with sterility in the galactorrhea-amenorrhea syndrome and scleropolycystosis of ovaries of central genesis is to be performed differentially taking into account pineal gland state.
New possibilities of the use of surgical lasers in obstetrics
Authors: Fatkullin I. F.
Published: October 2021

The laser welding suture of peritoneum in pregnants and in women in labor with high risk of pyo-septic complications is used in cesarean section operation. In the basic group the postoperative complications are three times as little than in the comparison group. The promise of the use of the biological laser @welding@ in obstetrics and gynecology to improve technology and results of surgical treatment especially in delivery of women with high risk of pyo-septic complications is noted.
To the technique of double contrasting of the stomach
Authors: Abdulkhakova D. I.
Published: October 2021

A modification of the technique of double contrasting of the stomach is described. More than 2000 patients were examined by the method of stomach inflation. The technique is simple and easy to carry out in the conditions of both a polyclinic and a hospital. It has a fairly high information content in the diagnosis of various pathological conditions of the stomach.
On the features of the clinical picture of traumatic brain injury during alcohol intoxication
Authors: Kutsenok I. K.
Published: October 2021

Examined 251 patients with traumatic brain injury in the acute period, received in a state of alcohol intoxication. In 109 victims, alcohol intoxication simulated a picture of traumatic brain damage. Observation in dynamics, additional examination using the methods of craniography, echoencephalography, carotid angiography, as well as lumbar puncture and examination of the fundus made it possible to exclude traumatic injuries of the skull and brain in patients of this group.
Cerebral complications in combined trauma of the skull and musculoskeletal system
Authors: Zakirov Y. A. , Valeev E. K. , Krylov V. E.
Published: October 2021

From 1972 to 1982, we observed 297 patients with concomitant trauma to the skull and musculoskeletal system. Of these, 9 were diagnosed with fat embolism, 3 with cerebral thromboembolism, 36 with intracranial subdural hematomas.
About parasystole in children
Authors: Mamish A. M. , Burba N. E.
Published: October 2021

In recent years, there has been an increase in interest in parasystole in children, since this form of arrhythmia is much more common than expected. Parasystole is an independent type of arrhythmia with the activity of the ectopic center. Diagnosis of parasystole is possible only with an electrocardiographic study. ECG signs of parasystole are characterized by a variation of pre-ectopic intervals, the presence of a common time divider for interectopic intervals and confluent complexes. Parasystole is combined with various arrhythmias, but most often with extrasystole. Electrocardiographic diagnosis of parasystole in children is complicated by the irregularity of sinus rhythm and physiological characteristics of the rhythm frequency according to age groups. In practice, the differential diagnosis between parasystole and extrasystole is especially difficult and in some cases is possible only with the help of functional tests.
Once again about "fetal birth trauma" from an obstetrical perspective
Authors: Khasanov A. A.
Published: October 2021

One of the main objectives of obstetrics - reduction of perinatal morbidity and mortality - is still far from being solved. Mortality and disability of children in some regions of the country are several times higher than in many developed countries of the world. In recent years there has been evidence of a high incidence of birth injuries to the nervous system of the fetus.
10th European Congress of Radiology
Authors: Kamalov I. I.
Published: October 2021

This congress was devoted to the problems of clinical radiological diagnostics, modern computed tomographic and ultrasonic diagnostics, radionuclide research, interventional radiology with recognition of diseases of the spinal cord and brain, cardiovascular system, thorax, abdomen, kidneys and skeletal musculature. The physical aspect of medical (electron, proton) imaging was also touched upon.
About the article by Dr. med. A.M. Kholodkovsky "Outpatient abortion"
Authors: Selitsky S. A.
Published: October 2021

Despite the many years of experience and observations of A.M. Kholodovsky, on which his article "outpatient abortion" is based, it is hardly possible to share his principled attitude in this matter and it is hardly possible to agree with the justifications of this attitude and the separate provisions put forward.
State of audition organ and upper respiratory tracts in workers of tyre production
Authors: Tikhonova A. G.
Published: October 2021

The lesions of upper respiratory tracts are diagnosed in 37,6% of the examined persons depending on the age and length of work. The direct dependence of professional hypoacu- sis on the length of work is stated in 31% of the workers.
On the question of foreign bodies of the abdominal cavity
Authors: Kulikov B.
Published: October 2021

On January 13, 1931, Melania, A-va, 39 years old, was admitted to the Bolotov Soviet Hospital with complaints of pain and swelling in the epigastric region.
Prof. M. S. Malinovsky and Prof. M. G. Kushnir. Manual on operative obstetrics. Gosmedizdat. 1931, p. 480, c. 5 p.
Authors: Kozlov I.
Published: October 2021

After the publication of the last edition of "Operational obstetrics" prof. Many years have passed by Fenomenov, and thus a major defect has arisen in the supply of a practicing obstetrician with a guide to operative obstetrics, which would more or less satisfy the needs of obstetric medical practice. This defect is now becoming even more noticeable for two reasons: 1) the almost complete absence of solid manuals on obstetrics in general, which, for example, should be fully considered "Obstetrics" by prof. V.S.Gruzdev and 2) a significant progressive increase in the number of doctors who have to pay great or exclusive attention to this type of medical care (doctors of special obstetric departments, consultations, medical specialists in large hospitals in factories, factories, state farms, collective farms, district doctors). The lack of manuals and textbooks on obstetrics is especially acute in medical universities, where the mastery of the discipline by students often occurs only "from the words" of the teacher and where, therefore, the activation of teaching methods is reduced to replacing lectures with group tutoring conversations. This is why the release of the peer-reviewed Guideline. However, we think that the work that has appeared should be welcomed also because in itself it is of great value and not only for the student, - the future district doctor, as the authors thought when compiling the Guide, but also for a practical doctor. in his day-to-day obstetric work, and for the postgraduate obstetrician at the Postgraduate Postgraduate Institutes, and for the teacher.
The experience of the medical council in the examination of the results of treatment of trauma patients
Authors: Takhavieva D. G.
Published: October 2021

The experience of the Republican Medical Council on the examination of long-term results of treatment of traumatological patients in the TASSR is highlighted. The outcomes were studied and the analysis of the treatment of injuries was given. patients with isolated, multiple and combined fractures, treated in various medical institutions of the republic, both in inpatient and outpatient settings. Errors in diagnosis and treatment were identified, which, to one degree or another, adversely affected outcomes. The most common errors and complications, their causes are analyzed, recommendations for their prevention are given.
Ргinzhогn, Hans. Psychotherapie. Voraussehungen, Wesen, Grenzei. Verlag Georg Thieme. Leipzig. 1929. Seite 334. Preis geh. RM. 14.—, geb. RM. 15.75.
Authors: Galant I.
Published: October 2021

Ргinzhогn, Hans. Psychotherapie. Voraussehungen, Wesen, Grenzei. Verlag Georg Thieme. Leipzig. 1929. Seite 334. Preis geh. RM. 14., geb. RM. 15.75.In his voluminous book about psychotherapy, its prerequisites, essence, boundaries, Prinzhorn does not give anything new.
The First All-Union Oncological Congress
Authors: Aber S.
Published: October 2021

The I-th All-Union Oncological Congress, held on July 8-12, 1931 in Kharkiv, attracted the urgent attention of not only the medical mass, but also the general public. Prominent scientific forces took part in the work of the congress, such as Professors Petrov (Leningrad), Anichkov (Leningrad), Abrikosov (Moscow), Zilberberg (Odessa), Shirokogorov (Baku), Bukhman (Rostov n/A), Harmandaryan (Kharkov), Melnikov (Kharkov), Bykhovsky, Harshak (Kiev) and many others. others, representatives of many clinics, institutes and research departments, delegates of workers of industrial enterprises and socio-professional organizations. The exceptional interest of the planned program issues attracted the most remote periphery to the congress (Vladivostok, Tiflis, Uzbekistan, Armenia, Petrozavodsk, the Southern Coast of Crimea, the Caucasus, the Urals, etc.).
Recovering treatment of extensive defects of hand nerves
Authors: Rozovskaya T. P. , G. G. G. , Latypova N. A.
Published: October 2021

From the results of treatment of 32 patients in the substitution of extensive (820 cm) defects of median, ulnar nerves on the level of a lower one third of forearm apd hand by means of different methods of autonervous plasty the authors conclude that the proposed methods recover sensitivity states necessary for the vital activity and improve trop- hicity of hand tissue.
The use of osteal transplants in microsurgery
Authors: Bogov A. A. , Topyrkin V. G. , Akhtyamov I. F. , Plakseichuk A. Y.
Published: October 2021

A number of new transplants on vascular limbs lateral border segment of scapular bone, greater trochanter segment, transplant from posterior surface of distal epiphysis of radial bone, transplant from posterior surface of styloid process have developed and employed. The given transplants are used for revascularization of osteosynthesis place and substitution of osseous tissue defects, permitting to reduce the terms of curability of patients with the sequels of traumas or diseases of osteoarticular apparatus of limbs.
Compression-destruction osteosynthesis for fractures of long bones
Authors: Khabibullin A. G.
Published: October 2021

In the treatment of fractures of long tubular spines, transosseous compression-distraction osteosynthesis (TCDO) has become widespread in recent years. We would like to share our own experience of using this method in the conditions of the Central District Hospital. We observed 64 people with fresh fractures of long bones, who underwent CHKDO in the trauma department of the Central District Hospital. Most of them were people of the most working age - from 14 to 60 years old.
Participation of alveolar macrophages in pathogenesis of tuberculous inflammation
Authors: Tukhvatullin R. M. , Zubairova L. D.
Published: October 2021

The role of macrophages has been shown in all stages of tuberculous inflammation. They are the first protective barrier during the contact with myc- robacteries, they perform the functions of antigenp- resentating cells, stimulating the development of the specific clone of T-lymphocytes, macrophages being activated by T-lymphocyte lymphokines become the principal effector cells. The basis cytotoxic mechanisms are lysosomal, oxygen-dependent and tumor necrosis factor (TNF). Depending on the virulence and immunogenecity of mycrobacteries all these mechanisms may exert protective and injurious effect. Delayed sensitivity plays the main role in surrorting this process. The study and regulation of the function of macrophages remain the perspective trend of phthisiology.
Consumer goods in the service of preventing blindness
Authors: Preobrazhensky V.  V.
Published: October 2021

On the threshold of the second five-year plan, when the Union, under the leadership of the party, is fighting for mastering the achievements of the first five-year plan and for building a new way of life, we, ophthalmologists, have big tasks before us to eliminate social eye diseases trachoma and blennorrhea.
Transport processes in liquid baths and gas/liquid interfaces due to impinging gas and plasma jets
Authors:   , Qian Feng
Published: October 2021

Impinging gas or plasma jets on molten metal are commonly encountered in such processes as BOF (Basic Oxygen Furnace) and electric arc furnace steelmaking. Understanding the mechanism of transport phenomena, such as heat and mass transfer associated with the oxygen jet (in the BOF) impinging on molten metal and the arc jet (in the electric arc furnace), is important for process optimization. The interface shape is important because it determines the interaction of the metal bath with the surroundings. Using a physical model consisting of water and air, the liquid surface deformed by the impinging gas jet was characterized in the experiments. A computational model was also developed to predict interface deformation, the flow field in the gas jet, and the shear driven flow field in the liquid bath. To simulate the slag/metal layers as found in the BOF and the electric arc furnace, water/corn oil and water/kerosene combinations were used in the physical modeling studies. The influence of physical properties of the two liquids on the interface shape and flow fields was studied under various impinging jet conditions. An existing phenomenological model for the penetration depth was extended for small jet exit height to jet diameter ratios. Heat transfer from a liquid bath due to an impinging gas jet has also been investigated. Both numerical calculations and experiments were utilized to characterize the heat transfer from impinging jet on a liquid bath. Air jets with liquid baths of silicone oil, liquid metal (Amalloy-203) and water were modeled. The thermal behavior of the bath was characterized as function of jet characteristics and bath liquid properties. A numerical model was also developed to characterize transport processes for impinging arc jets on solid metal surfaces. The heat transfer from the arc to the metal surface was calculated. Computational results were obtained for varying arc current magnitudes and anode-cathode distance. Shorter arc length is shown to be more efficient for transferring heat to the anode.
Pengaruh Kepribadian Proaktif, Kinerja Kerja, Promosi Diri terhadap Kesuksesan Karir Karyawan Ponpes Surya Global
Authors: Anindita Hafidz , Muafi Muafi
Published: October 2021

Tujuan dari penelitian ini adalah untuk menguji dan menganalisis kepribadian proaktif, kinerja kerja, dan promosi diri terhadap kesuksesan karir pada Pondok Pesantren Mahasiswa Stikes Surya Global Yogyakarta. Data yang diambil dari penelitian ini didapatkan dari wawancara kepada 3 responden serta melalui kuesioner yang berdasarkan skala Likert 5 poin, penyebarannya menggunakan 120 sampel karyawan yang berstatus sebagai karyawan tetap di Pondok Pesantren Mahasiswa Stikes Surya Global disebut dengan penelitian sensus, kuesioner yang kembali hanya sebesar 109 kuesioner. Alat bantu analisis yang digunakan adalah SmartPLS v. 3. 0. Dengan metode analisis SEM (Structure Equation Modeling). Hasil dari penelitian ini adalah kepribadian proaktif tidak memiliki pengaruh positif terhadap kesuksesan karir secara langsung namun memiliki pengaruh positif yang signifikan terhadap kinerja kerja yang mana kinerja kerja ditemukan memiliki pengaruh positif signifikan terhadap kesuksesan karir, selain itu promosi diri juga ditemukan memiliki pengaruh yang positif dan signifikan terhadap kesuksesan karir.
Model Empirik Efek Mediasi Kapabilitas Inovasi Dalam Meningkatkan Kinerja Pemasaran
Authors: Lutfi Lutfi , Ichwanudin Wawan , Nupus Hayati
Published: October 2021

Usaha Mikro Kecil dan Menengah (UMKM) merupakan segmen terbesar pelaku ekonomi nasional dan berperan penting bagi masyarakat dalam menghadapi krisis ekonomi. Penelitian ini bertujuan untuk mengetahui peranan variabel kapabilitas inovasi dalam memediasi pengaruh orientasi pasar terhadap kinerja pemasaran, studi pada UMKM makanan dan minuman (kuliner) di Kota Cilegon. Data responden yang akan menjadi sampel dalam penelitian ini adalah UMKM makanan dan minuman (kuliner) di Kota Cilegon dengan metode observasi, wawancara, dan kuesioner, sedangkan teknik pengolahan dan analisis data menggunakan SEM dengan software smartPLS versi 2.0.m3. Temuan penelitian ini menunjukkan bahwa secara langsung orientasi pasar tidak berpengaruh signifikan dalam meningkatkan kinerja pemasaran, namun jika melalui variabel mediasi kapabilitas inovasi maka orientasi pasar berpengaruh poisitif dan signifikan terhadap kinerja pemasaran, dengan demikian maka variabel kapabilitas inovasi mampu memediasi pengaruh orientasi pasar terhadap kinerja pemasaran. Implikasi manajerial juga dibahas dalam penelitian ini.
THE EFFECT OF ACCOUNTABILITY OF RURAL FUND MANAGEMENT AND INTERNAL CONTROL TO PREVENT CORRUPTION IN VILLAGES OF BOJONGPICUNG DISTRICT - CIANJUR
Authors: Faraitody Teguh Dody , Bahtiar Dandi
Published: October 2021

The purpose of this study is to find out the effect of accountability of rural fund management and internal control to prevent corruption in villages at bojongpicung district of Cianjur regency. The objects of the study are village heads, village devices, Village Representative (BPD) and BPD members and community leaders. The sampling criteria are people who understand and are directly involved in the management of the Rural Fund. The sample consisted of 66 people consisting of 11 Village Heads, Village officials, village secretaries, regional executives, technical implementers, BPD and BPD members, as well as community leaders in each village. Then conducted interviews and distributing questionnaires. The results showed that partially Accountability of Rural Fund Management and Internal Control had no effect on Corruption Prevention Efforts, as evidenced by the results of the significance test above 5%. Likewise, the test results simultaneously and together the two variables do not have an effect on the Efforts to Prevent Corruption Crimes, as evidenced by the significance test results above 5%. The basic of theory are the Ministry of Home Affairs Regulation Number 20 of 2018 concerning Rural Financial Management, the Auditing Book (Practical Guidelines for Examination of Accountants by Public Accountants) by Sukrisno Agoes and the Corruption Education Book for Universities published by the Ministry of Education and Culture of the Republic of Indonesia.
Stakeholder Analysis in Tourism Development Bintan Regency During the Pandemic COVID-19
Authors: Mahadiansar Mahadiansar , Wijaya Andy Fefta , Wanto Alfi Haris
Published: October 2021

In improving the welfare of the people in border areas, the development of the tourism sector has an impact on long-term economic growth which has been the largest regional income source in Bintan Regency. The importance of interaction and stakeholder actors involved in tourism activities during the COVID-19 pandemic. The purpose of this study is to analyze the condition of stakeholder actors in tourism management in Bintan Regency. The research method used a qualitative approach with stakeholder analysis using NVivo 12 with data collection techniques in the form of interviews with stakeholders and using existing secondary data which was carried out in-depth analysis. The results showed that 3 components (who, when, and how) showed a significant correlation between stakeholders in tourism development in Bintan Regency, namely the local government which regulates the executive management as a facilitator. Then the involvement of community groups as active participation to support the development of travel bubble-based tourism in the border region of the country, then the involvement of the private sector who maintain and regulate health protocols in the spread of COVID-19. Furthermore, the alternative is to improve stakeholder relations in the future to make efforts to approach harmonious communication between stakeholders in the tourism sector in Bintan Regency.
Validation of the Dutch leakage score as a predictor of anastomotic leakage in intestinal surgery in a third level hospital
Authors: Barker-Antonio Alan , Jarquin-Arremilla Arturo , Cruz Elias Hernandez , Garcia-Manzano Roberto Armando , Davila-Ruiz Ediel Osvaldo
Published: October 2021

Background: Intestinal surgery can present multiple complications that can lead to patient death; therefore, it is important to design early detection strategies to reduce complications in patients with intestinal anastomosis and thus avoid patient death. The aim of this work is to evaluate the diagnostic performance of the Dutch leakage score in 125 patients with intestinal anastomosis as a predictor of anastomotic leakage.Methods: In a sample of 125 patients undergoing intestinal anastomosis, demographic variables were identified and the Dutch leakage score was applied. Sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were obtained using a 2×2 table.Results: The Dutch leakage score was positive in 23.2% (29 patients) of whom 24 had anastomotic leakage and 5 had no anastomotic leakage. It presents a sensitivity in the test of 100%, a specificity of 95%, a positive predictive value of 82.7%, a negative predictive value of 100%. The diagnostic accuracy is 96%.Conclusions: The Dutch leakage score is a versatile tool, inexpensive, easy to apply and available in any hospital center. It is capable of early diagnosis of anastomotic leakage. It favors early re-intervention, improves prognosis and survival, decreases hospital stay and health care costs.
COVID-19 disease and comorbidity: an outcome? A study on Indian population in a COVID care hospital
Authors: Makkar Namrata , Singla Amit , Jain Ajeet , Upreti Lalendra , Sherwal B. L.
Published: October 2021

Background: The world has been severely affected by the novel coronavirus disease (Covid-19). Continuously rising number of cases has put a significant strain on healthcare resources of all countries of the world. Preliminary studies show that people suffering from comorbid conditions are at a relatively higher risk of severe disease and poor outcome.Methods: We studied the risk of ICU admission in 152 Covid-19 positive patients with comorbidity compared to those without comorbid conditions. We studied effect of old age (>65 years), male sex, presence of at least one comorbidity, presence of multiple comorbidities, diabetes mellitus, hypertension, CAD, respiratory disease, neurological disease, skin disease, and hypothyroidism on outcome of coronavirus disease with two tailed Student’s t-test, odds ratio, Chi-square test was used to test significance of results at 95% confidence interval 95% (95% CI). Fisher’s test was also used if one expected value (row total × column total/grand total) was less than 5.Results: In this study, 23 (15.13%) required ICU care. We found higher odds of ICU admission in Covid-19 patients in case of presence of comorbid condition (OR=7.3, 95% CI=2.674, 20.038), diabetes mellitus (OR=2.8, 95% CI=1.035, 8.028), hypertension (OR=1.3, 95% CI=0.396, 4.258), coronary artery disease (OR=2.3, 95% CI=0.430, 12.978) and malignancy (OR=6.5, 95% CI=1.516, 28.54). Case fatality rate (CFR) of those with comorbid conditions was higher (7.55) compared to those without comorbidity (3.03).Conclusions: This study shows that presence of comorbid conditions in Covid-19 positive patients results in significantly higher risk of ICU admission and poor outcome.
Evaluating effects of allo-vedic preparation Raj Nirwan Bati on symptomatic cases of COVID-19 at a tertiary level health care facility in rural setting of northern India
Authors: Kumar Raj , Yadav Ramakant , Rawat Ramakant , Singh Naresh P. , Sharma Indra K. , Yadav Prashant
Published: October 2021

Background: The present pandemic of COVID-19 has created a huge pressure on the current health system of the world as the burden is increasing exponentially day by day. Study evaluated the effect of the novel allo-vedic formulation named Raj Nirwan Bati (RNB) on the clinical symptoms, microbiological, bio-chemical, haematological and radiological profile of patients of COVID-19.Methods: Prospective single arm, non- randomized clinical trial was conducted which enrolled 40 reverse transcriptase-polymerase chain reaction (RT-PCR) confirmed patients of severe acute respiratory syndrome corona virus-2 (SARS-CoV-2). Each patient was given one dosage of RNB twice a day for 10 days. Patients were evaluated on the clinical symptoms, microbiological, bio-chemical, haematological and radiological profile of patients of COVID-19. Cochran’s Q tests was used to assess statistical significance.Results: The study revealed that 31 (77.5%) of the COVID-19 cases were having mild, 6 (15%) moderate and 3 (7.5%) having severe form of illness. The association between absence of clinical symptom (fever, cough, breathlessness, sore throat, fatigue and myalgia) and the day of evaluation (first, fifth and tenth day) after start of RNB intervention was found to be statistically significant (p<0.001, p<0.001, p=0.002, p<0.001, p<0.001 and p<0.001) respectively. Thirty (75.0%) of the cases on RNB intervention became negative for SARS-CoV-2 after day 5 on naso-pharyngeal and oro-pharyngeal RT-PCR testing (p<0.001). Statistically significant association was observed only for changes in proportion of cases with elevated lactate dehydrogenase (LDH) values and C-reactive protein (CRP) positive from day 1 to day 10 of RNB intervention (p<0.001).Conclusions: RNB may be considered a drug to fight against COVID-19.
Assessing intravenous midazolam for conscious sedation during cataract surgery
Authors: Dhabarde Madhuri V. , Mhatre Archana S. , Waychal Abhijeet D. , Patahkar Deepanjali P.
Published: October 2021

Background: A large number of geriatric populations above the age of 50 worldwide suffer from cataract. Cataract starts with short-sightedness and gradually worsens resulting in blurring of vision and inability to visualize and distinguish fine details. Surgery is the only available treatment for cataract. Anaesthesia is essential during cataract surgery to minimize pain caused during surgical procedure and to achieve favourable surgical outcome. The current investigation was aimed towards assessing the performance of intravenous midazolam used for conscious sedation during cataract surgery along with retrobulbar block.Methods: Current study is a randomized double blinded study performed for duration of 6 months on 60 patients undergoing cataract surgery at Terna medical college and hospital. Patients were divided in two groups; group M received 0.02 mg/kg midazolam diluted to 5 ml, group N received 5 ml normal saline before cataract surgery. All vital hemodynamic parameters were observed after 5 minutes of sedation, immediately after block administration and after every 15 minutes till the end of the surgery to assess the effect of sedation. Patients and surgeons satisfaction levels were also documented post-surgery.Results: Patients who were sedated with midazolam prior to cataract surgery along with block exhibited a significant decrease in hemodynamic parameters like SAP, DAP and heart rate which indicated effective sedation. Anxiety level also significantly decreased in the patients who received midazolam. No major adverse or intra-operative events were observed in the patients who received midazolam.Conclusions: Sedation with midazolam provides haemodynamic conditions favourable for cataract surgery along with high level of patient and surgeon satisfaction.
Prevalence of retinopathy of prematurity: a 3-year retrospective study
Authors: Patel Aval S. , Mehta Rishi
Published: October 2021

Background: Retinopathy of prematurity (ROP) is a vasoproliferative disease of premature infants which leads to permanent blindness. Early screening is needed to diagnose ROP and prevent blindness.Methods: Retrospective study was conducted in 225 neonates from January 2018 to December 2020. All neonates with birth weight <2000 gm and/or gestational age <38 weeks were included. History of oxygen given to neonates and presence of sepsis in neonates was noted. The infant’s pupil were dilated. Fundus examination was done. All the data was entered in MS-Excel 2016 and analyzed by SPSS (version 19). Chi-square test was done to calculate p value.Results: Out of total of 225 neonates, 137 (60.88%) were males and 88 (39.12%) were females. The gestation age of neonates (in weeks) ranged from 25 to 40 (mean: 32.35). The birth weight of neonates (in grams) ranged from 570 to 2500 (mean: 1460). 21 (9.33%) were found to have ROP. The male neonates found with ROP were 16 (11.67%) while females were 5 (5.68%) (p>0.05). Out of 148 neonates who were given oxygen 19 (12.83%) developed ROP (odds ratio: 5.52). Out of 42 neonates who had sepsis, 2 (4.76%) developed ROP (odds ratio: 0.43).Conclusions: The prevalence of ROP was 9.33%. The prevalence is showing a decreasing trend. ROP is not affected by gender. Oxygen given to neonates is associated with greater ROP. But sepsis in neonates is not associated with development of ROP.
Clinical study of multiple myeloma and treatment responses in a tertiary care centre
Authors: Giridhar Immanni S. M. , Yadlapalli C. Deepak , Gullipalli Muralidhar , Mushini Venkatesh , Sarma Yerraguntla S. , Chakradhar Mamidi
Published: October 2021

Background: Multiple myeloma (MM) evolves from Monoclonal gammopathy of unknown significance (MGUS), a premalignant clinical condition. Second to non-Hodgkin’s lymphoma, MM is the most common haematological malignancy. The aim of the study was to review the clinical profile and response of individuals treated for MM from this part of country.Methods: We evaluated data of patients with MM managed between 2013 and 2019 at a tertiary care cancer hospital in Rajamahenderi, India. Data regarding demographic variables, clinical features, disease characteristics and treatment details were collected and analysed.Results: Total of 54 patients with MM were managed. Mean age was 59.4 years. Males accounted for 63%. Bone pain (90%) was the most common symptom. Elevated serum creatinine was noted in 16.7% and M band in 42 (77.8%). X-ray of skull showed lytic lesions in 41 (75.9%). Mean haemoglobin value was 8.8±1.9 g/dl and serum calcium was 9.12 mg/dl. Majority of subjects, 44 (81.48%) belong to stage IIIA, 9 (16.67%) to stage IIIB, and 1.85% to stage IIA of Durie Salmon staging system. No response was noted in 17 (31.5%), 4 (7.4%) subjects had a progressive disease even on treatment, and 8 (14.8%) subjects had a very good partial response. Median survival of subjects belonging to DSS stage II was 17 months, IIIA was 11.037 months and stage IIIB was 17.463 months.Conclusions: MM has an early onset in India. Though MM is an incurable disease, many promising treatment options are there which lead to increase in survival. Early treatment helps in improving mortality rates, better quality of life and decreases disease burden.
Comparative study of echocardiography and electrocardiography criteria for detecting left ventricular hypertrophy in hypertensive patients
Authors: Golla Abhishek , V. S. Ramkumar , P. Ashok Kumar , S. Ravindranath , Ramaiah Indira , N. Veena , Gurala Rajashekar R. , Hussain Kazi Jawad , Adithya Vikram
Published: October 2021

Background: The study aimed to compare seven different electrocardiogram (LVH) criteria for diagnosing left ventricular hypertrophy (LVH) with echocardiogram as diagnostic standard in hypertensive patients.Methods: This was a hospital-based, cross-sectional study conducted in out-patient department and at medical wards of a tertiary care hospital at Bangalore. The study was carried out for a total duration of 12 months. All hypertensive patients underwent examination for prevalence of LVH using echocardiogram and ECG. Seven different ECG criteria were applied to diagnose the presence of LVH. Then the specificity, sensitivity, kappa measurement value, positive predictive value and negative predictive value for all criteria was calculated subsequently.Results: Out of the 100 patients studied, 34 had LVH as diagnosed by echocardiography. Sokolow-Lyon criteria had a sensitivity of 35% and specificity of 94%. Cornell voltage had a sensitivity of 26% and specificity of 95%. Modified Cornell voltage had a sensitivity of32% and specificity of 94%. Framingham adjusted Cornell voltage, Minnesota code and Cornell product had a sensitivity of 23.5% and specificity of 98.4%. Framingham score had a sensitivity of 38% and specificity of 95.4%.Conclusions: It can be concluded that among all the different criteria used in the study, Framingham score showed better sensitivity compared to others. In the evaluation of hypertensive patients for LVH, the role of ECG with all the commonly used criteria is of limited value and echocardiography is the method of choice.
Histopathological study of soft tissue tumours in a tertiary health centre in southern part of Assam
Authors: Tapadar Khadija S. , Deka Manoj K. , Chaubey R. N. , Sheikh Shah A. , Choudhury Gargi R. , Choudhury Madhusmita
Published: October 2021

Background: Soft tissue tumors are defined as mesenchymal proliferations which occur in the extraskeletal non-epithelial tissues of the body, excluding the viscera, coverings of brain and   lymphoreticular system. The objective of this study was to study the histopathological features of soft tissue tumors and to study the occurrence of soft tissue tumors in relation to age, sex and anatomical site.Methods: This study comprised of 89 cases studied over a period of two years. All soft tissue tumors, their gross features, microscopic findings were analysed in detail. Soft tissue tumors were divided into benign and malignant categories and further sub typing were done according to World Health Organization (WHO) classification. The distribution of soft tissue tumors according to the age, sex and site of occurrence was studied.Results: Out of 89 cases of soft tissue tumors, 76 cases were benign, 4 cases belonged to intermediate category and 9 cases were malignant. Adipocytic tumors formed the largest group constituting 39 cases. Vascular tumors were the second commonest (26 cases) followed by peripheral nerve sheath tumors (11 cases). The benign tumors were seen in younger age as compared to malignant tumors. Malignant soft tissue tumors was seen to be more common in male than female and pleomorphic sarcoma and liposarcoma was commonest (3 cases each).Conclusions: Benign tumors were more common than malignant. The most common benign tumors were lipoma followed by hemangioma and schwannoma. The most common malignant tumor was pleomorphic sarcoma. The benign tumors were seen in younger age as compared to malignant tumors.