bluuebunny/crossref_metadata_2025 huggingface dataset:
A machine learning-based nano-photocatalyst module for accelerating the design of Bi2WO6/MIL-53(Al) nanocomposites with enhanced photocatalytic activity
Authors: Zhai Xiuyun , Chen Mingtong
Published: June 2023

A machine learning-based nano-photocatalyst module for accelerating the design of Bi2WO6/MIL-53(Al) nanocomposites was constructed by four steps. An online web service was established to quickly predict the photocatalytic activity of Bi2WO6/MIL-53(Al).
Direction- and polarization-tunable spontaneous emission beneficial from diffraction orders of a square R6G-nanopore array
Authors: He Shijia , Wang Yi , Wang Tianyu , Wu Dongda , La Junqiao , Hu Jiang , Xiao Jiamin , Wang Wenxin
Published: June 2023

A directional and polarized spontaneous emission is modulated on a square R6G-nanopore array. 90° dissimilarity polarization emissions are achieved from two states of diffraction orders through the resonance energy match.
Tuning the charge carrier polarity of roll-to-roll gravure printed carbon nanotube-based thin film transistors by an atomic layer deposited alumina nanolayer
Authors: Zhang Wei , Shrestha Sagar , Parajuli Sajjan , Maskey Bijendra Bishow , Park Jinhwa , Yang Hao , Jung Younsu , Cho Gyoujin
Published: June 2023

Charge carrier polarity tuning in printed thin film transistors (TFTs) is a crucial step in order to obtain complementary printed devices.
Fabrication of a bifunctionalyzed Calotropis gigantea inspired Ag–Cu–Co trimetal oxide for the remediation of methylene blue, and its larvicidal and antibacterial applications
Authors: Nivetha A. , Sakthivel C. , Hemalatha J. , Senthamil C. , Prabha I.
Published: June 2023

A Calotropis gigantea supported Ag–Cu–Co trimetal oxide was synthesized for larvicidal, antioxidant, antibacterial and photocatalytic degradation studies.
Synthesis of α-allenic aldehydes/ketones from homopropargylic alcohols using a visible-light irradiation system
Authors: Jiang Dong-Fang , Zeng Xing-Xing , Li De-Feng , Wen Si-Miaomiao , Hu Ming-Hua
Published: June 2023

A visible-light irradiation tandem oxidative aryl migration/carbonyl formation reaction, mediated by K2S2O8 and visible-light photoredox catalysis, has been discovered.
Zinc-catalyzed transamidation and esterification of N-benzoyl cytosine via C–N bond cleavage
Authors: Gaware Sujeet , Chatterjee Rana , Kapdi Anant R. , Dandela Rambabu
Published: June 2023

An efficient transamidation and esterification using N-benzoyl cytosine has been developed via zinc catalytic C–N bond cleavage.
The role of terminal ligands in the slow relaxation of magnetisation and luminescence thermometry of dinuclear NdIII complexes
Authors: Bispo-Jr Airton G. , Gálico Diogo A. , Diaz-Rodriguez Roberto M. , Ovens Jeffrey S. , Sigoli Fernando A. , Murugesu Muralee
Published: June 2023

Magneto- and opto-structural correlations are used as tools to help understand how changes of the crystal field components acting on NdIII influences the slow relaxation of magnetisation and luminescence thermometry of NdIII dinuclear complexes.
Lewis base-catalyzed trifluoromethylsulfinylation of alcohols and phenols: modular synthesis of trifluoromethanesulfinate esters
Authors: Liu Wen , Xing Shuya , Ni Shao-Fei , Ma Cheng , Fan Qiujin , Ye Zhiyong , Zhao Yanchuang , Ouyang Ting , Bai Ying , Shao Xinxin
Published: June 2023

Herein, a Lewis base catalyzed trifluoromethylsulfinylation of alkyl alcohols and phenols with N-(trifluoromethylsulfinyl)phthalimide, which is a bench stable electrophilic trifluoromethylsulfinylating reagent, is presented.
An integrated MDC–FO membrane configuration for simultaneous desalination, wastewater treatment and energy recovery
Authors: Elnahas Mostafa , Elawwad Abdelsalam , Ghallab Ayat , Ettouney Reem , El-Rifai Mahmoud
Published: June 2023

Novel four-chambered MDC–FO configuration for water desalination and wastewater treatment using a sequential anode–cathode feed. Best performance at high water salinity and low-strength wastewater.
Self-powered sensors for biomarker detection
Authors: Li Jiaxuan , Xu Lingling , Zou Yang , Li Zhou
Published: June 2023

Herein, the working principle of self-powered biosensors and their application in the detection of biomarkers are systemically reviewed. In addition, the current research status and shortcomings are summarized to provide reference for future design.
Accelerating water oxidation on BiVO4 photoanodes via surface modification with Co dopants
Authors: Barzgar Vishlaghi Mahsa , Kahraman Abdullah , Österbacka Nicklas , Usman Emre , Erdem Emre , Sennaroğlu Alphan , Wiktor Julia , Kaya Sarp
Published: June 2023

On the BiVO4 photoanode surface, oxygen vacancies modified by cobalt incorporation have a remarkable impact on the water oxidation activity and charge injection efficiency.
A PdPt nanoparticle-decorated thiol-functionalized MOF with high peroxidase-like activity for colorimetric sensing of d-glucose and chlorophenol isomers
Authors: Luo Yuanqing , Zhou Shiwen , Chen Weiwei , Liu Yaqin , Feng Hongru , Pan Yuanjiang
Published: June 2023

Colorimetric sensors for d-glucose and chlorophenol isomers were constructed under near-neutral conditions based on a thiol-functionalized MOF decorated with PdPt nanoparticles with efficient peroxidase-like activity.
Tuning the rare-earth UiO-66 metal–organic framework platform for white light emission
Authors: Ajoyan Zvart , Bicalho Hudson A. , Donnarumma P. Rafael , Antanovich Artsiom , Howarth Ashlee J.
Published: June 2023

A trimetallic rare-earth cluster-based metal–organic framework is synthesized that emits red, green and blue emission simultaneously.
The dark neutral medium is (mostly) molecular hydrogen
Authors: Liszt H. , Gerin M.
Published: June 2023

Context. More gas is sometimes inferred in molecular cloud complexes than is represented in HI or CO emission, and this is called dark neutral medium (DNM).

Aims. Our aim is to extend a study of DNM along 13 directions in the outskirts of Chamaeleon by determining the atomic or molecular character of the DNM along a larger sample of sightlines.

Methods. We acquired ALMA ground rotational state absorption profiles of HCO+ and other molecules toward 33 compact extragalactic continuum background sources seen toward the Galactic anticenter, deriving N(H2)=N(HCO+)/3 × 10−9 as before. We observed J = 1−0 CO emission with the IRAM 30m telescope in directions where HCO+ was newly detected.

Results. HCO+ absorption was detected in 28 of 33 new directions and CO emission along 19 of those 28. The five sightlines lacking detectable HCO+ have three times lower  and . Binned in EB–V, N(H2) and N(DNM) are strongly correlated and vary by factors of 50–100 over the observed range EB–V ≈0.05–1 mag, while N(HI) varies by factors of only 2–3. On average N(DNM) and N(H2) are well matched, and detecting HCO− absorption adds little to no H2 in excess of the previously inferred DNM. There are five cases where 2N(H2) < N(DNM)/2 indicates saturation of the HI emission profile. For sightlines with WCO ≥ 1 K-km s‒1, the CO-H2 conversion factor N(H2)/WCO = 2–3 × 1020 cm‒2 /(1 K-km s‒1) is higher than is derived from studies of resolved clouds in γ-rays.

Conclusions. Our work sampled primarily atomic gas with a mean H2 fraction ≈1/3, but the DNM is almost entirely molecular. CO fulfills its role as an H2 tracer when its emission is strong, but large-scale CO surveys are not sensitive to H2 columns associated with typical values N(DNM) = 2–6 × 1020 cm‒2. Lower XCO values from γ-ray studies arise in part from different definitions and usage. Sightlines with WCO ≥ 1 K-km s‒1 represent 2/3 of the H2 detected in HCO+ and detecting 90% of the H2 would require detecting CO at levels Wco ≈ 0.2–0.3 K-km s‒1.
Features of the results of conductometric studies of apple juices
Authors: Nikulina Svetlana , Fateeva Natalia , Cherekanova Evgenia , Verizhnikova Tatiana , Smirnova Ekaterina , Vasyukov Alexander , Nazarova Irina
Published: June 2023

By the conductometric method, the dependence of the specific electrical conductivity (χ) of five apple juice samples on the volume fraction (φ) of apple juice in a solution with distilled water. The dependence χ in the range φ from 0 to 1 acquires a power-law character (the correlation coefficient is close to 1), since a significant part of the mineral composition of apple juices consists of various organic acids. The technique fully complies with the principles of “green” chemistry, since the “waste” is apple juice diluted with distilled water.
Effective management of the sale of agricultural products as the basis for food security in the region
Authors: Selina Marina , Shikhova Oksana
Published: June 2023

This study formulated the concept of food security in the region and analyzed the food independence of the Vologda Oblast and the economic availability of food. It is believed that in order to solve the problems associated with the provision of food to the population of the region, it is necessary to effectively manage the sale of agricultural products. The role of a commodity brand, or rather its participants-producers of agricultural products, in ensuring the food security of the region is modeled. Calculation of coefficient estimates of indicators of food security factors, their integration in the form of four main indicators of the role of the brand, and an aggregated comprehensive assessment of the role of the brand. Along with this, a methodology was tested for assessing the role of product brand participants, agricultural producers, in ensuring food security and the quality of life of the population of the region based on the results of a consumer survey. The practical significance of the study follows from the importance of solving financial and economic issues of agricultural development to ensure the food independence of the region.
Hematological and hemostasiological characteristics of piglets during the plant feeding phase
Authors: Tkacheva Elena , Medvedev Ilya
Published: June 2023

Preservation of all parameters of homeostasis in pigs of any age is largely ensured by the state of their hematological parameters. The parameters of primary hemostasis are of great importance in this. For piglets in the phase of plant nutrition, a decrease in the intensity of peroxidation in the blood due to an increase in its antioxidant protection is characteristic. At this stage of development, the levels of total protein, urea, albumin, triglycerides in the blood increase in piglets, and a stable sufficient level of glucose is maintained. At the end of early ontogenesis in piglets, there is a clear balance between the development of platelet aggregation properties and the severity of the disaggregation characteristics of blood vessels. The balance of changes in platelet aggregation and the severity of control over it from the walls of blood vessels found during the phase of plant nutrition is an important basis for maintaining the balance in the activity of individual components of hemostasis in piglets.
Platelet functions in tethered heifers in the process of growing them
Authors: Shumova Maya , Medvedev Ilya
Published: June 2023

In the course of growing heifers on tethered content, there is a tendency to some decrease in the severity of platelet lipid peroxidation due to an increase in their antioxidant protection. In platelets, this is accompanied by activation of the actin-myosin system, a high level of adenosine phosphates, and their intense secretion in the case of platelet participation in hemostasis. The observed heifers showed a tendency to increase the hemostatic functions of platelets, manifested in the blood and in vitro. The revealed slight increase in platelet activity in tethered heifers is caused by maturation during rearing of surface and intracellular mechanisms of platelet participation in hemostasis and microcirculation processes.
Comparative assessment of the tillage quality of commercial and combined plow bottoms
Authors: Streltsov S.V. , Mustyakimov R.N. , Ayugin N.P. , Proshkin V.E. , Salakhutdinov I.R.
Published: June 2023

The paper presents the results of comparative field studies of the tillage quality of commercial and combined (for the primary layer-by-layer tillage) plow bottoms in terms of plowing quality parameters, in particular, in terms of the completeness of crop residue incorporation and the density of tilled soil layers. The results of the study are directed to a wider introduction of technical means intoproduction that provide conditions for resource saving when performing the primary tillage with the use of mouldboard technology.
The study of metal oxidation process when metal is exposed to waste products of farm animals
Authors: Ayugin N.P. , Morozov A.V. , Mustyakimov R.N. , Molochnikov D.E. , Semashkin N.M. , Zlobin V.A.
Published: June 2023

The article is devoted to the study of the corrosion process rate of steel parts in livestock and poultry buildings, primarily, dung removers, which are operated and exposed to a chemically aggressive environment. The issues of metal loss of parts which are in contact with waste products of cattle, pigs and poultry are considered. The results of the influence of corrosion processes on loosening torque increase of the threaded joints of dung removing equipment for livestock and poultry farms are also presented. The research results can be used in design and repairs of farm dung removers.
Comprehensive assessment of water management situation in the water bodies of Simferopol
Authors: Ivanyutin Nikolay , Volkova Natalya , Popovich Valentina
Published: June 2023

The article presents the results of comprehensive analysis of water management situation at the water storage facilities of the Simferopol city. The study included digitization of reservoirs, survey of these water bodies and their coastal zones, determination of accumulated water composition and properties in field and laboratory conditions, assessment of their environmental sustainability. In the course of the work a list of ponds was identified, primarily in need of measures, aimed at improving their level of environmental safety and maintaining a comfortable urban environment.
Development of a mathematical model of the process of sorting municipal solid waste using elements of similarity of technical systems
Authors: Karelin Artem , Kozhemyachenko Alexander , Lemeshko Mikhail , Semenov Nikolay
Published: June 2023

The article studies the similarity of ensuring the technical condition of the solid municipal waste sorting line system. The functional dependence of the productivity of the waste sorting line is given, partial expressions and numerical values of the criteria for similarity of the functioning of the sorting process are obtained. A generalized criterion of similarity of the state of the solid municipal waste sorting process is also obtained, the nature of the influence of the parameters of functional dependence on the value of the output characteristic is investigated.
Features of acclimatization of Ligustrum L. in the Middle Urals
Authors: Tishkina Elena , Semkina Lydia
Published: June 2023

The article is devoted to the introduction and acclimatization of Ligustrum vulgare L. in the Middle Urals since the creation of the collection in 1960. At that time, the average annual temperature was only 1°C and Ligustrum vulgare L. froze, grew again and fruited in favorable years. It was possible to create an introduction population by families, but, nevertheless, in 1998 all plants died from the return of cold weather and frosts. The study of the growth and development of privet has been resumed since 2016. Several geographical samples of seedlings grown without irrigation were studied. It turned out that the sample from Barnaul turned out to be the best in all indicators, close values of growth and development of plants from seeds from Samara, and the worst indicators of plants from seeds obtained from Kazan. Average values were noted in Ligustrum ibota (Kaliningrad reproduction), while agrotechnical care (watering and weeding) revealed the maximum height in a sample from Penza.
A study on bamboo as the alternative material for floating PV system structure
Authors: Hendarti Religiana
Published: June 2023

This paper presents the study of bamboo as an alternative material for structure of floating PV system. Bamboo is selected as it is used for traditional floating house structure by Indonesian people. Additionally, bamboo is a fast growing vegetation and it can be found easily here. To investigate its potential, the study includes the characteristics of bamboo material such as its the physics and mechanics, the application of bamboo as a structure material and subsequently the component of PV structure to analyse the feasibility of bamboo material as the floating PV structure. In the analysis, the following aspects are studied: floatation system, configuration and mooring configuration.
The role of innovative technologies in the development of the fuel and energy industry of the Russian Federation
Authors: Antipin Dmitrii , Zhiqiang Miao
Published: June 2023

The efficiency of fuel and energy companies depends to a large extent on the level of automation of technological processes, information security, and cost reduction through the introduction of innovative technologies. The article considers the problems of using innovation in the enterprises of the fuel and energy sectors, the analysis of the main indicators of the level of their development. The article offers directions for the introduction of innovations in the fuel and energy complex of the country. The influence of the use of innovative technologies on the process of drilling wells was studied. A model for cost optimization based on the use of innovative technologies to automate the processes of collecting and processing information obtained during drilling was developed.
Analysis of the implementation of the National project “Housing and Urban Environment” of the Tobolsk city
Authors: Podkovyrova M.A. , Ogneva Y.E.
Published: June 2023

With large-scale urbanization of natural-territorial complexes there are a number of ecological, social and economic problems associated with increasing the density of urban development, reducing the level of urban improvement, increasing air pollution, water basins and urban soils; flooding, waterlogging, etc.; dilapidated housing; accumulation of household waste; loss of vegetation cover and, ultimately, reduced comfort of the urban population. In this regard, the authors of the article propose methods of developing tools for the implementation of the strategy of sustainable development of the city of Tobolsk with its approbation in a number directions, factors and indicators.
Parametrization of temperature inversion over Krasnoyarsk city
Authors: Belolipetskii Victor , Genova Svetlana
Published: June 2023

Atmospheric pollution is associated with weather conditions. Meteorological processes make a significant contribution to the creation of unfavorable meteorological conditions (NMU). NMUs are a special shortterm combination of meteorological factors contributing to the accumulation of pollutants in the surface layer of atmospheric air. We draw a particular attention to the temperature stratification of the lower layers of the atmosphere which can cause a temperature inversion – an increase in air temperature with altitude. Temperature inversion limits the vertical dispersion of harmful impurities in the atmosphere. Observational data show that the increased level of air pollution in the city of Krasnoyarsk is most pronounced in winter with temperature inversion and weak winds (no more than 1-2 m/s). To predict periods of increased concentration of pollutants in the boundary layer of the Krasnoyarsk atmosphere we consider a numerical algorithm for determining the time intervals of formation and destruction of temperature inversion based on a onedimensional vertical model.
Update of the generalized environmental assessment and inertial forecast for the development of a cluster of urban areas of the Bogorodsky urban district of the Moscow region within the framework of the system “Ecology, environment and public health”
Authors: Rodionov Stanislav , Kostesha Vladimir , Suvorova Anna , Chesnokova Arina , Shevchuk Artem , Michurina Nadezhda , Amosova Antonina , Nurova Oksana
Published: June 2023

The article presents an update and a generalized geo-ecological assessment of the Bogorodsky urban district of the Moscow region (the former Noginsky was abolished) at the time of 2021-2022. The indicators of the ecological state of the territories are considered from the standpoint of the realities of the current years. A comparison was made of the geo-ecological situation of the territories of small towns of compact residence in the Noginsk district for 2011-2014 and the current geo-ecological situation of the territory of small towns of the Bogorodsk urban district of the Moscow region (the former Noginsk was abolished) for 2021-2022. Data on the incidence of the population and environmental pollution are analyzed from the standpoint of causal relationships of direct and indirect correlations between diseases of the respiratory, digestive and genitourinary systems. Also, for ecodiagnostics, the dominant concepts of toxicology are used, such as the reaction rate and the response of a particular individual organism to a stimulus. A new municipal specialized subprogram “Ecology and the Environment” for 2023-2027 with the introduction of new indicators aimed at protecting the environment is considered. A look at the scenarios and inertial forecast for the development of environmental sustainability of urbanized territories of small towns in the study area is given.
Development and justification of parameters of a microwave convective hop dryer
Authors: Novikova G.V. , Mikhailova O.V. , Prosviryakova M.V. , Storchevoy V.F. , Goryacheva N.G. , Fedorischev A.A.
Published: June 2023

To solve the problem of low energy efficiency and the absence of small-sized hop dryers, a microwave convective continuous-flow hop dryer has been developed with reasonable parameters that allow preserving the consumer properties of hops. The scientific innovative idea of implementing the technology of drying hops in the working chamber of a microwave hop dryer, made in the form of tiered rotors located between stationary nonferromagnetic bases, forming coaxial resonators in which a traveling wave from microwave generators is excited, is considered. The rotors are made in the form of perforated non-ferromagnetic outer and inner shells, where ceramic perforated partitions are rigidly installed in the annular space, allowing to concentrate radiation energy in raw materials and reduce radiation losses. Having calculated the dimensions of the coaxial resonator, having created its three-dimensional model in the Compass 20 program, we imported it into the CST Microwave Studio program to substantiate the electrodynamic parameters. A hop dryer with a capacity of 5 kW microwave generators with spiral decelerating systems will ensure uniform drying of hops in compliance with electromagnetic safety, with a capacity of 100 kg/h when the rotor is located without microwave energy sources between two coaxial resonators to comply with a process duty cycle of 0.5.
Dynamics of fouling of plastic waste fragments by microorganisms in the Gulf of Finland
Authors: Kaurova Z.G. , Petrova M.S. , Taimusova E.N. , Mkrtchyan M.E.
Published: June 2023

In recent years, the problem of the aquatic environment pollution with synthetic polymers - plastic and microplastics - has become more urgent than ever, which causes an increasing interest of the scientific community in this topic, both in our country and abroad. The development of organic synthesis chemistry at the beginning of the last century led to the emergence of synthetic polymers – plastics; the chemical properties of plastic, making it an inexpensive, durable, and useful material, led to its widespread, mass distribution, but they are also the cause of difficulties with its disposal – the decay, decomposition, and disposal of many types of plastic takes decades, which much lower than the production rate of new plastic. As it is known, plastics are materials that are synthetic or natural high-molecular compounds (polymers); the term “microplastic” refers to particles of synthetic polymers or plastic copolymers (less than 5 microns), they are insoluble in water and non-degradable. Such characteristics of microplastic components as the area, the particle surface relief, the type of polymer will affect the biofilm formation rate. This indicator also is influenced by the flow rate, the bio-productivity of the waters, and the position of the particles in the water column.
Ecological plasticity of safflower varieties in contrasting natural and climatic conditions of Western Kazakhstan
Authors: Limaskaya V.B. , Shektybayeva G.H. , Orynbayev A.T. , Kasenova A.S.
Published: June 2023

This research was carried out within the framework of the scientific and technical program BR10764991, “Creation of highly productive varieties and hybrids of oilseeds and cereals based on the achievements of biotechnology, genetics, physiology, and biochemistry of plants for their sustainable production in various soil and climatic zones of Kazakhstan,” under the budget program 267, “Increasing the availability of knowledge and scientific research.” The article presents the results of ecological variety testing of safflower in the arid conditions of Western Kazakhstan. Safflower is a drought-resistant oilseed crop that can produce a stable crop of oilseeds with an oil content of 27-38% in the conditions of the West Kazakhstan region. The main purpose of this scientific work is the systematic study of the selection material of safflower, with the identification of sources of valuable traits and properties based on ecological selection, and the creation of new competitive and patentable varieties adapted to the agroecological conditions of the region. The article presents the yield and the main elements of the structure of the yield of oilseeds of isolated safflower samples. The biological yield of safflower seeds in the nursery of ecological variety testing ranged from 6.4 to 12.0 c/ha. The article summarizes the results of ecological variety testing of safflower selection from the Kazakh Research Institute of Agriculture and Plant growing, the Research Institute of Agriculture of the South-East of the Volgograd State Agricultural Academy, the Krasnovodopadsky agricultural experimental station, and the Aktobe agricultural experimental station. These varieties were evaluated in this nursery based on their main economically valuable traits.
Veterinary and sanitary control during storage and sale of grain crops on the example of rye
Authors: Bazhenova I.A. , Makarova T.N. , Chernyshova L.V. , Ulitina O.S.
Published: June 2023

The problem of grain preservation is extremely relevant today. Due to the increase in the population, the task of ensuring food security arises, based on the production and rational storage of grain, since a large number of agricultural products are stored without provision of the necessary storage conditions. The grain quality is maintained in compliance with the storage rules, and it becomes available throughout the year. The method of grain storage varies in temperature and humidity. Storage affects grain quality, percentage of moisture, protein and fat, color, lipoprotein content, biochemical and metabolic changes, germination rate at the end of storage. During storage, the moisture content of the grain should be minimal to prevent its germination and insect infestation.The main purpose of grain preservation is to prevent possible quantitative and qualitative losses by preserving and/or improving certain physiological characteristics.
Ensuring technological sovereignty in the Russian wine industry and corruption risks
Authors: Shashkova Anna V. , Kudryashova Ekaterina V. , Solovtsov Alexey O.
Published: June 2023

The agro-industrial complex is often included in the list of economic sectors most exposed to corruption risks. Viticulture and winemaking share with the agro-industrial complex a tendency to corruption potential. The prestige and cultural characteristics of wine production increase not only the investment, but also the corruption attractiveness of this industry. The text provides specific examples of corruption in the wine industry from Russian and foreign practice. The state supports the wine industry, focusing on the expansion of vineyard areas at the moment. Nevertheless, winemaking is inevitably connected with technology and a legislative framework has been created to support the technological development of the industry, including in the context of ensuring technological sovereignty. The authors point out the need to consider corruption risks that have already been identified in the industry to prevent their negative impact in the future on achieving the goals ensuring technological sovereignty.
The political economy of technological sovereignty: On the transformation of the concept into the scientific category
Authors: Stozhko K.P. , Nekrasov S.N. , Stozhko D.K. , Shilovtsev A.V. , Makarova T.N.
Published: June 2023

In the context of the current geopolitical crisis and a new reality formation, technological sovereignty is of particular importance for ensuring national security. This concept is relatively new in science and has not yet been developed. Its semantic content remains controversial and ambiguous, as well as ideas about the ways and methods of its formation and strengthening. In this regard, the article presents a comparative analysis of the “technological sovereignty” concept, based on its comparison with the similar concepts of “technosphere”, “national interests”, “national security”, “economic activity”. The lexical interpretation of “technological sovereignty” as a new concept and as a scientific category is given. Special attention is paid to endogenous and exogenous factors determining the formation of “technological sovereignty”, the need for its more targeted complementation with development goals (totality, system, structure of interests), as well as the definition of its subject and object nature.
It staff turnover: Causes and management tools
Authors: Alexandrova N.A. , Ksenofontova T.Yu. , Zharkova E.A. , Alexandrov V.A. , Kukhar V.S.
Published: June 2023

The article is devoted to the analysis of the turnover causes and retention tools for IT specialists during the period of deep transformation of the corresponding segment of the labor market. For companies, a serious challenge is the outflow of highly qualified specialists and a large number of vacancies that stimulate excessive inter-organizational mobility. The purpose of this study is to develop a system of tools that can keep the turnover rates of IT specialists at an acceptable level. The study was conducted in the IT departments of three regional divisions of large federal organizations in December 2022 by the survey method (questionnaire and Exit interview). According to the study, the main quit causes are getting a more interesting offer from another employer and dissatisfaction with wages. The authors proposed the use of retention tools, which are grouped into the following groups: motivating, team-building, career, supportive. The article has practical value, since the presented tools can be used in various organizations to prevent excessive turnover.
Can Transvaginal Cervical Elastography predict the success of
induction of labor with oxytocin?
Authors: Halilzade Inci , Halilzade Mohammad İbrahim , Sert Ümit Yasemin , Alkan Mihriban , Keskin Hüseyin Levent
Published: June 2023

ObjectiveWe aimed to show whether elastography can be analternative,
although the Bishop score used in the follow-up of labor induction success with
oxytocin is a relative concept.

Material and methods This prospective case-control study includes 56 cases
admitted to a tertiary maternity hospital for induction between March and June
2019. Cervical elastography was applied to patients before induction. Induction
success in pregnant women who underwent induction with oxytocin was accepted to
be greater than Bishop 9. The cases were divided into two groups as successful
(n=28) and unsuccessful (n=28) induction, and their
elastosonographic findings were compared.

ResultsIn 28 cases with successful induction (Bishop >9, and
vaginal delivery occurred in 28), the mean stiffness of the cervix in
measurements from four regions was 13.6 ±3.7 kPa in the measurement of
the cervix with the elastography method before induction was started, while this
value was measured as 14.9 ± 3.1 in cases where induction was
unsuccessful (t- value: -1.321, p=0.194).

Conclusions Our study showed that pre-induction stiffness of the cervix
cannot predict the success of labor induction with oxytocin. More studies with
larger samples are needed to arrive at a decent conclusion. In addition, results
can be more assuring with the developing technique and sensitivity of
elastography.
Breast Implant-Associated Tumors
Authors: von Fritschen Uwe , Kremer Thomas , Prantl Lukas , Fricke Alba
Published: June 2023

In addition to anaplastic large T-cell lymphomas (BIA-ALCL), other implant-related tumors have been described for some years. Squamous cell carcinoma (SSC) and B-cell lymphomas occurred in
very rare cases. The unexplained pathogenesis as well as the unclear individual risk profile is an ongoing source of uncertainty for patients and physicians. The pathogenesis of the tumors
is still largely not understood. While BIA-ALCL occurs more frequently with textured breast implants, other tumors were also observed with smooth implants and at other implant sites.
Multiple potential mechanisms are discussed. It is suspected that the etiology of a chronic inflammatory response and subsequently immunostimulation is multifactorial and appears to play a
key role in the malignant transformation. Since there are currently no sufficiently valid data for a specific risk assessment, this must be done with caution. This article presents the
incidence, pathogenesis, as well as the level of evidence according to the current state of knowledge, and evaluates and discusses the current literature.
Artificial Intelligence for Computer-Aided Drug
Discovery
Authors: Kate Aditya , Seth Ekkita , Singh Ananya , Chakole Chandrashekhar Mahadeo , Chauhan Meenakshi Kanwar , Singh Ravi Kant , Maddalwar Shrirang , Mishra Mohit
Published: June 2023

The continuous implementation of Artificial Intelligence (AI) in multiple
scientific domains and the rapid advancement in computer software and hardware,
along with other parameters, have rapidly fuelled this development. The
technology can contribute effectively in solving many challenges and constraints
in the traditional development of the drug. Traditionally, large-scale chemical
libraries are screened to find one promising medicine. In recent years, more
reasonable structure-based drug design approaches have avoided the first
screening phases while still requiring chemists to design, synthesize, and test
a wide range of compounds to produce possible novel medications. The process of
turning a promising chemical into a medicinal candidate can be expensive and
time-consuming. Additionally, a new medication candidate may still fail in
clinical trials even after demonstrating promise in laboratory research. In
fact, less than 10% of medication candidates that undergo Phase I trials
really reach the market. As a consequence, the unmatched data processing power
of AI systems may expedite and enhance the drug development process in four
different ways: by opening up links to novel biological systems, superior or
distinctive chemistry, greater success rates, and faster and less expensive
innovation trials. Since these technologies may be used to address a variety of
discovery scenarios and biological targets, it is essential to comprehend and
distinguish between use cases. As a result, we have emphasized how AI may be
used in a variety of areas of the pharmaceutical sciences, including in-depth
opportunities for drug research and development.
Digitale Kontrolle der Adhärenz für die Behandlung von Drogenmissbrauch
Authors: Simojoki Kaarlo , Nowak Manfred , Pitten Stephan , Baum Klaus
Published: June 2023

Ziel der Studie Die Kontrolle der Adhärenz gehört unabdingbar zur Therapie drogenabhängiger Patient:innen. Die dazu meistgenutzte Matrix ist der Urin, bei deren Gewinnung bis vor kurzem die Sichtkontrolle beim Urinieren oder bei der Einnahme einer Urinmarkersubstanz notwendig war, um mögliche Manipulationen aufzudecken. In den letzten Jahren wurde ein telemedizinisches Verfahren entwickelt (Ruma Digital-System (Pro), Ruma GmbH, Deutschland), bei dem der/die Patient:in während einer zweiminütigen Smartphone-Videoaufzeichnung mit offline-Kontrolle eine Urinmarker-Substanz schluckt (Polyethylenglykole) und die nachfolgende Urinprobe selbstständig an das zuständige Labor verschickt. In der vorliegenden Beobachtungsstudie wurde überprüft, ob es eine Patientengruppe mit bestimmten Merkmalen ist, die das telemetrische Verfahren akzeptiert, inwieweit das Ruma Digital-System (Pro) für Interessierte auch nach mehrmaliger Nutzung als Kontrolle der Beigebrauchsfreiheit vorstellbar ist und welche Vor- und Nachteile aus dem telemetrischen Verfahren hervorgehen.

Methodik Die Gruppenzuordnung der Patient:innen erfolgte auf freiwilliger Basis. Insgesamt 133 Patient:innen (48 Frauen, 85 Männer) nahmen in einer Kontroll- (KG, n=65) und einer Interventionsgruppe (IG, n=68) teil. IG verwendete das Ruma Digital-System (Pro), bei KG wurden die Urinproben unter Sichtkontrolle genommen. Unmittelbar nach der ersten (TK1) und nach der 5. Urinkontrolle (8 bis 12 Wochen, TK5) wurde der psycho-sozial orientierte Fragebogen PARADISE 24 eingesetzt, in der Interventionsgruppe wurden zusätzlich Fragen zum Umgang und der Zufriedenheit mit dem Ruma-Digital-System (Pro) gestellt. Die Antworten dieser Fragen wurden in Quartilen der PARADISE 24 Ergebnisse zum Zeitpunkt TK5 differenziert.

Ergebnisse Die Patient:innen, die sich für das Ruma Digital-System (Pro) entschieden, waren überwiegend jünger, männlich und hatten geringere psycho-soziale Schwierigkeiten. Im beobachteten Zeitraum verstärkte sich die Akzeptanz für das telemedizinische Verfahren. In dieser Gruppe kam es zu folgenden Veränderungen: Die überwiegende Mehrheit der Patient:innen hatte ein verringertes Schamgefühl bei der Urinkontrolle, konnte ihren Alltag besser bewältigen und würde das Verfahren weiterempfehlen. Bei ca. zwei Drittel der Patient:innen kam es zu einer Zeitersparnis infolge des Wegfalls von Anreise- und Wartezeiten für die Kontrolle.

Schlussfolgerung Das telemedizinische Verfahren stärkt die Selbstwirksamkeit derjenigen Patient:innen, die das System akzeptieren. Es ist psychologisch gegenüber der Sichtkontrolle weniger belastend und kann auch im Falle einer pandemischen Lage für die Kontrolle der Therapietreue uneingeschränkt genutzt werden.
Geburt im hebammengeleiteten Kreißsaal eines
Perinatalzentrums – Lernkurve, Ergebnisse und Benchmark
Authors: Andraczek Theresa , Magister Susann , Bautzmann Sandy , Poppke Stephanie , Stepan Holger , Tauscher Anne
Published: June 2023

Einleitung Die Mehrzahl der Geburten in Deutschland erfolgt in einer
Klinik. Seit 2003 wurde in Deutschland die Geburtshilfe durch das Angebot eines
Hebammenkreißsaals (HKS) in einigen Kliniken erweitert. Ziel der Studie
war es, Unterschiede eines hebammengeleiteten und ärztlich geleiteten
Kreißsaals hinsichtlich medizinischer Parameter in einem
Perinatalzentrum Level 1 zu analysieren.

Material und Methoden Im Zeitraum von 12/2020 bis 12/2021
wurden retrospektiv alle im HKS begonnen Geburten analysiert und mit einer
primär ärztlich geleiteten Kontrollkohorte verglichen. Als
Zielgrößen wurden geburtshilfliche Interventionen,
Entbindungsmodus und -dauer, Gebärposition sowie das maternale und
neonatale Outcome definiert.

Ergebnisse Der Anteil der im HKS gestarteten Entbindungen an der
Gesamtgeburtenrate betrug 4.8% (n=132). Die Mehrzahl der
Überleitungen erfolgte auf Wunsch der Gebärenden nach einer
effektiveren Analgesie (n=40, 52,6%). Bei ärztlich
indizierten Überleitungen (n=30, 39,5%)
überwogen Überleitungen aufgrund von CTG-Auffälligkeiten
(40%) und ausbleibender Wehentätigkeit nach vorzeitigem
Blasensprung (36,7%). 43,9% der Gebärenden konnten
erfolgreich im HKS gebären. Die Episiotomierate im ärztlich
geleiteten Kreißsaal war signifikant höher im Vergleich zum HKS
(p=0,019). Im übergeleiteten Kreißsaal wurden
signifikant mehr Periduralanästhesien durchgeführt als im
primär ärztlich und erfolgreich hebammengeleiteten
Kreißsaal, welche zudem keine signifikanten Unterschiede in der PDK-Rate
untereinander aufwiesen (p<0,001).

Schlussfolgerung Die Geburt in einem HKS innerhalb eines Perinatalzentrums
kann bei risikoarmen Schwangeren als gleichwertige Alternative zu der
primär ärztlich geleiteten Geburt angesehen werden.
Asymmetric Catalytic Hydroboration of Enol Carbamates Enables an Enantioselective Matteson Homologation
Authors: Ready Joseph M. , Kuznetsov Dmitry M.
Published: June 2023

A rhodium-catalyzed asymmetric hydroboration of enol carbamates yields α-boryl carbamates with a good enantioselectivity. The enol carbamate starting materials can be prepared with moderate Z-selectivity by using a modified Juila olefination; they can then be used as the resulting E/Z mixtures, taking advantage of the faster reactivity of the major Z-isomers in the directed hydroboration. Optically active α-boryl carbamates participate in a Matteson-type homologation with Grignard reagents, in which the O-carbamate is substituted, with high conservation of optical activity, to provide enantioenriched secondary boronic esters.
Sustainable Organocatalytic Processes to Access Alkyl SuFEx Click Hubs and Tetrasubstituted Carbon Centers: Potential Libraries for Multidisciplinary Applications
Authors: Bae Han Yong , Kim Woo Hee , Park Jin Hyun , Lee Sun Bu , Israr Muhammad , Koo Byeong Jun , Kim Soo Bok , Kim Soyeon
Published: June 2023

In this Account, we provide an overview of our recent achievements on sustainable organocatalysis. Our group has unveiled the effectiveness of specific organocatalysts under various environmentally benign conditions. We have found that N-heterocyclic carbene and phosphazene superbases exhibit favorable performances in bulk aqueous reaction environments. In addition, the use of organic superacid catalysts results in synergistic effects when hydrogen-bond donor catalysts are assembled in aqueous media. Moreover, we discovered that a neutral organic salt precatalyst can generate a potent silylium Lewis acid catalyst in situ, specifically under solvent-free conditions. These innovative, sustainable organocatalytic processes have successfully facilitated the conversion of raw starting materials into valuable compounds, including sulfur(VI) fluoride exchange (SuFEx) click hubs and tetrasubstituted carbon centers incorporating heteroatoms.

1 Introduction

2 Water-Accelerated N-Heterocyclic Carbene (NHC) Catalysis for β-Aminosulfonyl Fluorides

3 Water-Accelerated Phosphazene Superbase Catalysis for β-Sulfidosulfonyl Fluorides and γ-Geminal Dithioester-Incorporated Sulfonyl Fluorides

4 Water-Accelerated Synergistic Superacid Catalysis for α-Tertiary Amines

5 Solvent-, Metal-, and Purification-Free PPM (parts per million) Neutral Organic Salt Catalysis for Tertiary Cyanohydrin Derivatives

6 Conclusion
Regiodivergent Synthesis of Brominated Pyridylthiophenes by Overriding the Inherent Substrate Bias
Authors: Okano Kentaro , Hosoya Masahiro , Mori Atsunori
Published: June 2023

A regiocontrolled functionalization of a pyridylthiophene scaffold was accomplished. Regioselectivity for deprotonation of the pyridylthiophene was switched by changing the reaction conditions, including the metal amide base and the solvent. Subsequently, in situ transmetalation and halogen dance on the corresponding organometallic species were controlled by additives and the reaction temperature, as well as by the above reaction conditions. This method successfully enabled the synthesis of four iodinated constitutional isomers from a single starting material, 2-(5-bromo-2-thienyl)pyridine.
Catheter-Directed Thrombolysis Protocols for Deep Venous Thrombosis of the Lower Extremities—A Systematic Review and Meta-analysis
Authors: Duarte-Gamas Luís , Jácome Filipa , Dias Lara Romana , Rocha-Neves João , Yeung Kak K. , Baekgaard Niels , Dias-Neto Marina
Published: June 2023

Objective To summarize characteristics, complications, and success rates of different catheter-directed thrombolysis (CDT) protocols for the treatment of lower extremity deep venous thrombosis (LE-DVT).

Methods A systematic review using electronic databases (MEDLINE, Scopus, and Web of Science) was performed to identify randomized controlled trials and observational studies related to LE-DVT treated with CDT. A random-effects model meta-analysis was performed to obtain the pooled proportions of early complications, postthrombotic syndrome (PTS), and venous patency.

Results Forty-six studies met the inclusion criteria reporting 49 protocols (n = 3,028 participants). In studies that addressed the thrombus location (n = 37), LE-DVT had iliofemoral involvement in 90 ± 23% of the cases. Only four series described CDT as the sole intervention for LE-DVT, while 47% received additional thrombectomy (manual, surgical, aspiration, or pharmacomechanical), and 89% used stenting.

Definition of venogram success was highly variable, being the Venous Registry Index the most used method (n = 19). Among those, the minimal thrombolysis rate (<50% lysed thrombus) was 0 to 53%, partial thrombolysis (50–90% lysis) was 10 to 71%, and complete thrombolysis (90–100%) was 0 to 88%. Pooled outcomes were 8.7% (95% confidence interval [CI]: 6.6–10.7) for minor bleeding, 1.2% (95% CI: 0.8–1.7%) for major bleeding, 1.1% (95% CI: 0.6–1.6) for pulmonary embolism, and 0.6% (95% CI: 0.3–0.9) for death. Pooled incidences of PTS and of venous patency at up to 1 year of follow-up were 17.6% (95% CI: 11.8–23.4) and 77.5% (95% CI: 68.1–86.9), respectively.

Conclusion Assessment of the evidence is hampered by the heterogeneity of protocols, which may be reflected in the variation of PTS rates. Despite this, CDT is a low-risk treatment for LE-DVT.
Synthesis of Carbamoyl Azides from Redox-Active Esters and TMSN3
Authors: Li Yajun , Bao Hongli , Yuan Xiaobin , Qu Yanjie
Published: June 2023

An efficient method for construction of C–N bonds is reported here. The iron-catalyzed azidation of N-hydroxy phthalimide (NHP) esters provides a convenient approach for the synthesis of carbamoyl azides with good substrate scope and functional group tolerance. Both aryl carbon C(sp2) and alkyl carbon C(sp3) sources can be used deliver the carbamoyl azides. Mechanistic studies were conducted and a two-stage process was identified.
Simple and Efficient Synthesis of Highly Functional 2-Oxonicotino­nitriles from 2-Chloronicotinonitriles
Authors: Bardasov Ivan N. , Alekseeva Anastasiya U. , Sorokin Saveliy P. , Shishlikova Maria A. , Ershov Oleg V.
Published: June 2023

A simple strategy for the synthesis of 2-oxo-1,2-dihydropyridine-3-carbonitrile derivatives (2-oxonicotinonitrile, 3-cyanopyridone) in good yields by substituting the halogen atom with an oxime under mild conditions was developed. The proposed approach makes it possible to avoid the problems associated with the hydrolysis of easily modified groups, since the reaction is carried out in the absence of water.