bluuebunny/crossref_metadata_2025 huggingface dataset:
Uma análise da pericardite: aguda e recorrente
Authors: Braz Felipe Blanc , Silva Pedro Henrique Dias Rosa da , Ferreira Thomaz Mota Cabo , Siqueira Emilio Conceição de
Published: December 2023

Objetivo: Analisar as características da Pericardite aguda e recorrente. Revisão bibliográfica: O pericárdio é uma membrana de dupla camada que envolve o coração. O espessamento e a inflamação dessa membrana são chamados de pericardite. A pericardite aguda e recorrente é causada por uma inflamação ativa do pericárdio, que é idiopática na maioria dos casos. A pericardite aguda é a mais frequente entre as síndromes pericárdicas e é responsável por cerca de 5% de todas as internações no pronto-socorro por dor torácica aguda. A complicação mais frequente após a pericardite aguda é a pericardite recorrente ou incessante, relatada em cerca de 15 a 30% dos pacientes. Considerações finais: A pericardite aguda é uma causa relativamente comum de dor torácica aguda que pode ser prontamente avaliada pela anamnese completa complementada por eletrocardiograma e ecocardiografia, sendo a recorrência uma das suas principais complicações. Sua terapêutica é baseada na restrição de exercícios, anti inflamatórios não esteroidais (ibuprofeno ou aspirina) e colchicina com um inibidor de bomba de prótons a fim de proteção gástrica. Além disso, podem ser utilizados corticóides e há novas drogas como os anticorpos monoclonais anakinra, canacinumab e rilonacept.
DETERMINATION OF SEVERAL IMPORTANT PARAMETERS OF HOLLOW ELECTRODES ABNORMAL GLOW DISCHARGE PLASMA UNDER THE INFLUENCE OF MAGNETIC FIELD AT DIFFERENT GAS PRESSURES
Authors: Karim Pshtiwan M. , Sadiq Diyar A. , Al-Hakary Shamo K.
Published: December 2023

This paper investigates the impact of an axial magnetic field on several plasma parameters of hollow electrode argon abnormal glow discharge. The discharge is generated by applying a DC voltage ranging from 0-6KV. By varying the pressure and magnetic field strength (0-25mT), the plasma potential, frequency, and degree of ionization were measured. The plasma potential, frequency, and degree of ionization were evaluated using spectroscopic measurements of the electron temperature and density. The results of the experiment show that the plasma potential decreases as the magnetic field strength increases, while the plasma frequency increases for lower pressure but reaches a constant value for higher pressure due to the increasing number of excitation collisions among the plasma-charged particles. The degree of ionization, determined using the ideal gas law, shows a near-linear relationship with the axial magnetic field at both low and high pressure.
Los medallones báquicos del Museu Nacional d’Art de Catalunya.
Authors: García Martínez Saray
Published: December 2023

En el Museu Nacional d’Art de Catalunya se conservan dos relieves escultóricos de características similares conformados por una testa en relieve sobre un medallón marmóreo elíptico. Se desconoce la procedencia de ambos relieves y, hasta la fecha, no hay ninguna evidencia de que entraran a la colección del museo de manera conjunta. En este trabajo se propone revisar ambas piezas a nivel formal y compositivo, así como la documentación relativa a su ingreso. El estudio se complementa con un análisis arqueométrico y del estado de conservación para extraer más datos relativos al soporte con el cual se labran las piezas.
Nuevas propuestas de identificación en retratos de corte de los siglos XVII y XVIII del Museo del Prado
Authors: Puerto Mendoza Eduardo
Published: December 2023

El museo del Prado dispone entre sus fondos un elevado número de retratos de corte procedentes en su gran mayoría de la colección real. En el presente artículo se analizan algunas de estas obras de los siglos XVII y XVIII, sugiriendo nuevas identificaciones de los personajes representados y abordando el contexto en que fueron creadas, muy vinculado a los acontecimientos históricos y a las relaciones entre las familias reales
NEWCORONAVIRUS INFECTIONANDPULMONARYTUBERCULOSIS: CLINICAL CASES
Authors: Gulyaeva N. A. , Prokopiev E. S. , Fedotova L. P. , Simonov A. A.
Published: December 2023

At the end of 2019, an outbreak of a new coronavirus infection, SARS-CoV-2, emerged in the People’s Republic of China with the epicenter in the city of Wuhan, Hubei Province. On February 11, 2020, the World Health Organization determined the official name of the disease caused by the new coronavirus – COVID-19, and on March 11, 2020, announced the beginning of a pandemic caused by the SARS-CoV-2 infection. COVID-19 is a “young disease”, which determines the importance of studying the influence of chronic comorbid pathology on the risk of infection with SARS-CoV-2, the severity of the course and the likelihood of developing an unfavorable outcome of the disease. Accumulated data identify several risk groups for severe COVID-19. First of all, this applies to patients with concomitant chronic pathologies: diabetes, cardiovascular diseases, obesity, and others [5, 15]. Coinfections affecting the respiratory tract pose clinical dilemmas as well as diagnostic and therapeutic challenges. This article presents clinical cases of the course of a combination of COVID-19 infection and pulmonary tuberculosis. The new coronavirus infection was more severe in a female patient with newly diagnosed tuberculosis than in a female patient with a chronic tuberculosis process, which confirms a different influence of the pathological processes on each other.
MECHANISMS OF THROMBOTIC READINESS STATE FORMATION IN CARDIOLOGICAL PATIENTS WITH ACTIVE ONCOLOGICAL PROCESS
Authors: Ramazanova Z. H. , Parshina S. S.
Published: December 2023

Today cardiovascular diseases and oncopathology are leading causes in the structure of mortality worldwide. The complexity of diagnostics of haemocoagulation complications in this comorbid pathology remains an urgent problem at present. The aim of our study was to investigate the mechanisms of thrombotic readiness state formation using the thrombodynamics test on the example of patients with cardiovascular diseases (CHD, arterial hypertension) and aggravated oncoanamnesis depending on the activity of oncoprocess. The study was conducted in 100 patients aged 37 – 86 years: 60 patients with active oncoprocess (group 1) and 40 patients with oncoprocess in remission (group 2). Clinical, anamnestic and laboratory data were studied using a statistical analysis. The main attention was paid to the thrombodynamics test indicators (both velocity and structural). It was found that the most informative indicators of the haemostasis system state estimation in patients with cardiovascular pathology and aggravated oncoanamnesis depending on the oncoprocess activity are thrombodynamic indices both velocity and structural. Almost half of cardiological patients with an aggravated oncoanamnesis had a state of thrombotic readiness irrespective of the activity of the oncological process. These indices were higher in active oncopathology than in oncopathology in remission. At the same time no differences in the data of standard coagulogram in both groups could be revealed. Application of thrombodynamics test in cardiological patients with oncoanamnesis allows to reveal the states of thrombotic readiness and to establish the degree of influence of oncoprocess activity on the formation of this state, which demonstrates fundamentally new aspects of diagnostics of procoagulant states in patients of this profile.
ISCHEMIC STROKE AND HEMOSTASIS DISORDERS IN ONCOLOGICAL PROCESS: A LITERATURE REVIEW
Authors: Ammosova L. V. , Chugunova S. A.
Published: December 2023

Malignant neoplasms are associated with an increased risk of developing acute cerebrovascular accidents. This article provides a review of the literature on hemostatic disorders during oncological processes in patients with ischemic stroke. Cancer-associated stroke can develop for several reasons, including direct effects of the tumor, as well as indirectly through the development of blood coagulation disorders, concomitant infectious diseases, or complications of antitumor therapy. One of the most common pathogenetic mechanisms is cancer-associated coagulopathy. Trousseau syndrome is a variant of paraneoplastic syndrome, characterized by a state of hypercoagulability with the development of thrombosis that precedes the diagnosis of a malignant neoplasm or develops simultaneously with it. Cerebral ischemia in Trousseau’s syndrome is characterized by a multifocal pattern of lesions according to neuroimaging data. To date, there are no clear diagnostic criteria for cancer-associated stroke, which is often one of the first clinical manifestations of the oncological process. According to various studies, laboratory markers of hypercoagulability can serve as predictors of previously undiagnosed malignancy in patients with cryptogenic ischemic stroke. Currently, more and more attempts are being made to develop diagnostic scales based on clinical and neuroimaging characteristics of stroke to identify hidden oncological processes. Another important aspect of the issue remains the lack of evidence-based recommendations for the treatment of ischemic stroke associated with cancer. Given the prevalence of stroke in cancer patients, potentially poor functional prognosss, higher rates of post-stroke mortality and high relapse rates, further research into this issue is required.
A MORPHOMETRIC ANALYSIS OF LUNG COMPONENTS IN WHITE RATS WITH HYPOXIA COMBINED WITH THE NATURAL GAS IMPACT
Authors: Protsko A. V. , Shishkina T. A. , Naumova L. I. , Chikunova I. Yu. , Zadneprovskaya E. A. , Polina Yu. V.
Published: December 2023

The human respiratory system is daily exposed to various biotic and abiotic factors, and, first of all, there is damage to the cellular elements of the mucous membrane. Prolonged irritating effects are accompanied by inhibition of regenerative processes and subsequent morphofunctional restructuring of the structural components of the lungs. The aim of the study was to research the morphometric parameters of the structural components of the lungs of white laboratory rats at different periods of chronic simulated hypoxia combined with inhalation of natural gas from the Astrakhan field, at a concentration of 3 mg/m3. The study covered 94 white mongrel sexually mature male rats who were in conditions of chronic hypoxia combined with natural gas inhalation for 120 days. The animals were placed in a special seed chamber produced by the Erisman Institute with a volume of 200 liters with a variable composition of the air-gas mixture, and with a decrease in the oxygen concentration in the inhaled air to 17.5 %, natural gas from the Astrakhan field was supplied through a special nozzle. The animals were kept in experimental conditions lasting four hours a day for five days a week. For the manufacture of histological preparations, animals were anesthetized with sodium ethaminal (40 mg/kg weight). Lung tissue samples were fixed in a 10 % solution of buffered formalin. The preparations were stained with hematoxylineosin and Van Gison. The analysis and visualization of the obtained glass preparations was carried out using a ZeissAxioScopeA1 light microscope (Germany) and a LeicaAperioCS2 digital scanner of micropreparations with specialized software. It was determined that the initial significant changes were already formed by 60 days of experimental exposure. In one group of drugs, thickening of the interalveolar septa associated with the processes of edema formation and infiltration by cellular elements were noted, another group of drugs showed emphysemalike changes with stretched and partially torn alveoli. By day 90 of the experiment, a decrease in the airiness of the lung tissue was determined on all preparations, manifested by thickening of the interalveolar septa and a decrease in the diameter of the alveoli. By day 120, the changes identified in the early stages were progressively increasing: there were areas completely devoid of alveoli, other fields of vision showed alveoli with torn walls. On the part of the bronchi, the following pattern was determined: an increased thickness of the walls of the bronchi, mainly due to the mucous and adventitial membranes, followed by deformation of the bronchi of medium and small caliber and the formation of peribronchial infiltrates. The morphometric analysis confirmed that chronic hypoxia combined with natural gas inhalation causes significant changes in the structural components of the lungs.
STUDY OF THE PROBLEM OF CHILDREN’S EPILEPSY IN THE REPUBLIC OF SAKHA (YAKUTIA)
Authors: Pshennikova G. M.
Published: December 2023

Epilepsy is one of the most common diseases of the nervous system in children. According to WHO, more than 50 million people worldwide suffer from epilepsy. It is estimated that the proportion of the general population with its active form (that is, with recurrent seizures and the need for treatment) currently ranges from 4 to 10 per 1,000 people. Globally, 2.4 million people are diagnosed with this disease every year. In Russia, epilepsy affects more than 1 million people. The analysis of statistical data on the prevalence and incidence of epilepsy in children in the Republic of Sakha (Yakutia) was carried out. In Yakutia, the first epidemiological study of epilepsy in the pediatric population was conducted in 1985 by E.A. Krivogornitsyna. As a result of the survey, data were obtained on 322 children who were registered at the dispensary with neurologists and psychiatrists in 32 districts of the republic and the city of Yakutsk. According to the study of the epidemiology of epilepsy in children in 2004 (Baisheva G.M., 2004), the prevalence of epilepsy was 5.2 per 1,000 children of the Republic of Sakha (Yakutia), and the primary incidence was 114 per 100,000 children. Prevalence of epilepsy in children under 14 years of age in 2020 was 5.4 per 1,000 population, the primary incidence was 50 per 100,000 population. On average, from 2010 to 2020, the primary incidence of epilepsy in children is 80 per 100,000 population. The prevalence of epilepsy in adolescents aged 15 – 17 years averaged 10.4 %. The average value of primary morbidity in this group of children was 140 per 100,000 population. The organization of comprehensive medical care will make it possible to form a strategy for the management of epilepsy patients at the municipal and republic levels.
RISK FACTORS FOR THE DEVELOPMENT OF CARDIOVASCULAR DISEASES IN ADOLESCENTS IN YAKUTSK, SAKHA REPUBLIC (YAKUTIA)
Authors: Marinova L. G. , Roeva D. E. , Nakhodkina A. S.
Published: December 2023

The article presents data on the frequency of risk factors for cardiovascular diseases in adolescents. A statistical analysis was also conducted to determine the correlations between the risk factors when an individual has multiple risk factors. The following risk factors for cardiovascular diseases, already occurring frequently in adolescence, were evaluated: high blood pressure, overweight, elevated cholesterol levels, carbohydrate metabolism disorders, low physical activity, eating disorders, and stress perception. A total of 712 adolescents aged 15 –16 years were examined, including 360 girls and 352 boys, residing in the city of Yakutsk, Sakha Republic (Yakutia). The study revealed that among adolescents, low physical activity showed the highest frequency among the risk factors, followed by others in descending order: restrictive eating behavior, high cholesterol and glucose levels, overweight and obesity, and high stress perception. The differences found were based on gender, with boys being more susceptible to obesity. Correlation analyses using Spearman’s (rs) and Pearson’s (rp) coefficients and Pearson’s chi-square test were used to identify relationships between risk factors for cardiovascular diseases. The analysis showed that high blood pressure is associated with adolescents who have high body mass index. Gender-based analysis showed that girls are more prone to arterial pressure disorders and elevated cholesterol and glucose levels.
REGULATORY LEGAL CONDITIONS FOR THE DEVELOPMENT OF PRIVATE MEDICAL ORGANIZATIONS
Authors: Snegireva Yu. Yu. , Ananchenkova P. I.
Published: December 2023

The article considers changes in the legal regulation of medical activities, which entered into force on September 1, 2023. New regulatory legal conditions for the development of medical organizations assume that medical organizations participating in the state guarantee program will have the right to provide paid services. Previously, the current procedure assumed that medical organizations providing services under the compulsory medical insurance could provide paid medical care on different conditions than provided for by the state guarantee program. Therefore, the development of private medicine and the problems facing private medical organizations in modern conditions are relevant and require discussion. The purpose of this work is to consider the regulatory legal conditions for the development of private medical organizations in the Russian Federation at the current stage. The conclusion is that today a lot of work is being carried out by the professional community responsible for approving the procedures for the provision of medical care and clinical recommendations, which should be guided by all medical organizations operating in the domestic market of medical services. The infrastructural provision of medicine should meet the needs of the population, ensure the provision of medical care in the specified volumes by type and form and be effective.
THE MAIN STAGES OF DEPLOYMENT OF HYBRID AGGRESSION BY THE RUSSIAN FEDERATION AGAINST UKRAINE
Authors: Drozdyuk Yaroslav
Published: December 2023

A historical analysis of the hybrid aggression of the Russian Federation against Ukraine, which became the most dramatic event in the recent history of Ukraine, at the beginning of the third decade of independence, was conducted. The open armed actions of the Russian Federation against Ukraine caused new challenges not only to the national security of Ukraine, but also to the security of the world in general. Currently, the term "hybrid war" best characterizes the actions of the Russian Federation in relation to Ukraine. It is this type of warfare that combines not only military means, but also informational, economic, political, diplomatic, and humanitarian means. At the same time, the «hybrid wars» of the Russian Federation use many tools, starting from the spread of panic rumors to the mobilization of the potential of the church, agents of influence in the economy, political bodies or the use of so-called soft power.

The article analyzes the step-by-step process of the military conflict between the Russian Federation and Ukraine, starting with the occupation of the Crimean Peninsula, the open Russian-Ukrainian armed confrontation in the east of the Ukrainian state, and ending with a large-scale invasion of Ukraine. Within each of the stages, separate periods are distinguished, the evolution of which determined and changed the motives of the behavior of the Russian Federation and led to the beginning of hostilities. The Russian-Ukrainian war requires a complex scientific understanding, study and generalization of the experience of conducting military operations in the largest armed conflict in Europe since the end of the Second World War. Conclusions were made regarding the need to consolidate the efforts of the EU, the USA and other democratic states as a guarantee of preventing hybrid aggression by states that act from the position of force, rather than the force of law.
THE ROLE OF AGENT-BASED MODELING AND COMPUTER SIMULATIONS IN POLITICAL SCIENCE
Authors: Chornenkyi Oleksandr
Published: December 2023

It considers opportunities for using computer agent-based modeling in studies related to political process analyses. Gives information about the historical context of computer simulation based on agent model implementation, and emphasizes the significance of T. Shelling and R. Axelrod models. It is noted usefulness of this method is applied to complex dynamic system analysis, wherein participants have complex interconnections, and their behavior depends on the situation.

Gives information about an agent-based model's main elements, especially space and agents, and describes what they can represent. Draws attention to the importance of the researcher’s study goal understanding using this approach, which in turn affects the model parameters setting that determines model will be abstract, realistic, or mixed.

Considered opportunities applying agent-based modeling for the course of social and political processes forecasting, and showed the opinion of other researchers on this issue.

Provides examples of ten studies related to the analysis of various political processes, the authors of which applied this approach and their own agent models with different realism levels.

Shows possibilities applied of computer simulations for forecasting the results of future and reproducing the results of past elections, evaluating election campaign strategies, the emergence of ideological polarization, modeling political discourse, evaluating the effectiveness of implemented policies, analyzing the risks of social instability in the state under the influence of external and internal factors.

It is concluded that agent-based modeling can be a helpful tool in the hands of political scientists and noted that the use of this approach significantly expands the possibilities for analyzing complex political processes.
THE CRISIS OF LEGITIMACY FROM THE POINT OF VIEW ОF THE FUNNEL OF CAUSALITY
Authors: Shapovalenko Maryna
Published: December 2023

The problem of legitimacy of political institutions and institutions of state power is considered. Various approaches to determining the legitimacy of government are analyzed, but the main emphasis is on the level of trust and what exactly reduces the level of trust in government institutions Emphasis is placed on the factors that affect the fall of trust and lead to crisis phenomena in the political environment and destabilize society in general. The points of view of M. Weber, R. Dworkin and A. Buchann on legitimacy are compared, which give rise to different views on political obligations and normative conditions. A crisis of legitimacy is a situation in which the legality of the existing social order is questioned and distrust of the existing government is openly expressed, which demonstrates the inability of the government to assure society of the necessity and optimal functioning of existing state institutions. The reasons for the delegitimization of power are determined (the lack of proper representation of the interests of social groups and sufficient vertical mobility in the political system in combination with social inequality), which ultimately lead to the radicalization of attitudes in society, the strengthening of the opposition and, in general, distrust of state institutions The methodology of the “Funnel of Causality allows to combine different levels of society and take into account the effects of the environment. First of all, the macro level (economic development, the influence of geopolitical actors, historical traditions,national mewntality etc.), radical economic changes, the development of civil society, the political activity of various social groups, the growth of crisis phenomena, as a result of radical transformation. Due to the fluctuating nature of the country's political development during the years of independence, revolutionary situations arose, and the very legitimacy of the government, even at the macro level, was called into question.
THE DOCTRINE OF STATE AND LAW IN THE IDEOLOGICAL AND POLITICAL DOCTRINE OF CLASSICAL CONSERVATISM
Authors: Malkina Anna , Pastukhov Anton
Published: December 2023

This research paper explicates the basic doctrines of the State and law of classical conservatism, as well as the peculiarities of understanding and existence of the idea of the State, which follows from the conservative definition of the State. The characteristic components of this political institution are the categories of law, legal consciousness, political integrity, etc. The perception of understanding the conservative theory of the origin of the state, based on the social contract theory, as a logical continuation of the organic association of people to maintain social order and political stability, is crystallising. The latter principles are also the fundamental axiological determinants of the conservative ideological and political doctrine, whose manifestor and defender is the state. The author characterises the concepts of law and law, the conceptual basis of which is reduced to the moral sphere of existence. The main objective of the existence of laws is to protect rights and freedoms, as well as their institutional representation. At the same time, the author defines the peculiarities of understanding legal consciousness and political consciousness as fundamental elements of state-building processes. In turn, their fundamental features are historical and geographical locality, identity and conceptual authenticity, which are the basis for the constitution of heterogeneous forms of political systems. The tasks and structural elements of the theory of state in the ideological and political doctrine of conservatism are analysed. The author also identifies the institutional elements of social limitation of state power in the context of conservative doctrine, which include the church and civil society.
POLITICAL CAMPAIGNING AND PROPAGANDA ON TELEVISION: FEATURES OF USE
Authors: Honcharenko Maksym
Published: December 2023

The topic of political campaigning and propaganda on television is highlighted with an emphasis on methods, effectiveness and ethical aspects of influencing public opinion and political processes. Analyzes the various methods and tactics used in political campaigning on television, including emotional impact, imagery, and rhetoric, and examines their impact on shaping public opinion and audience behavior.

The work compares the practices of political campaigning in different countries and contexts, which makes it possible to highlight the main differences and similarities in approaches to the use of television campaigning. This analysis reveals the importance of political context and cultural characteristics for the formation of effective communication strategies through television. Such important ethical issues related to the use of television propaganda as freedom of information, manipulation of public opinion and the need to protect society from unwanted negative influence are considered. Particular attention is paid to the potential of technological change, transparency and the development of ethical standards to improve the practices of using television campaigning for political purposes.

The final conclusion of the work emphasizes the importance of studying and understanding the impact of television campaigning on public opinion and socio-political processes, as well as the need to observe ethical norms in the process of preparing and publishing material of a socio-political nature to ensure freedom of information and protection of democratic values in society.
Possibilities of application of cognitive-behavioral therapy to achieve remission in alcohol dependence
Authors: Vovk Viktoriya , Strashok Oleg
Published: December 2023

Topicality.

The problem of abuse of psychoactive substances and the search for effective means for its treatment remains an acute topic in modern psychiatry and narcology. To date, cognitive-behavioral therapy when applied to patients with alcohol addiction is one of the most promising methods of treatment. This method of treatment is aimed at preventing and minimizing relapse.

The purpose of this work was to study the possibilities of using cognitive-behavioral therapy to achieve remissions in alcohol addiction.

Materials and methods: modern literary scientific data were analyzed regarding the issues of indicators of the effectiveness of alcohol addiction treatment, understanding the concept of remission and its prognostic factors, the personality profile of addicted persons, and the direct application of cognitive-behavioral therapy to achieve remissions in alcohol addiction.

The results. The analysis of literature data showed that the duration, stability and quality of remissions are important for evaluating the effectiveness of alcohol addiction treatment. When a remission is established, such factors as the duration of anti-alcohol therapy, stress resistance, personality profile of the addict and supportive therapy are of prognostic value. Cognitive-behavioral theory views alcohol addiction as an inadequate way to cope with problems or needs. Cognitive-behavioral therapy for alcohol addiction uses a standard set of methods, educational coping strategies that take into account the identification and specificity of situations when coping is inconsistent, as well as training, modeling, role-playing and behavioral rehearsals. These methods are intended not only to increase the level of cognitive and behavioral coping, but also to facilitate the perception of external influences and improve adaptation in stressful situations. Learning coping skills to overcome their deficit, eliminating factors that can prevent overcoming a breakdown and ensuring their adequate application in practice is a necessary condition for the effective use of cognitive-behavioral therapy. The methods of this type of therapy make it possible to show the patient that social learning plays an important role in the development of rigid thinking and maladaptive behavior and are designed to develop and strengthen self-control.

Conclusions. Thus, the analysis of literary sources showed that cognitive-behavioral therapy for addicts is a short-term, structured method of psychotherapy aimed at developing the skills of controlling addictive behavior in patients with alcohol addiction in the conditions of forming and maintaining remission.
Associations of indicators of the physical component of health with clinical-neuroimaging data of patients who have suffered ischemic stroke in the vertebrobasilar basin
Authors: Shalabay Natalia , Shkrobot Svitlana
Published: December 2023

Summary. A stroke significantly worsens the quality of life of patients. An expert report from the Polish National Program for the Prevention and Treatment of Cerebral Stroke in 2001 recommends assessing quality of life during post-stroke rehabilitation. The authors report on parameters that may influence quality of life, in particular, age, gender, and functional status, including degree of disability, cognitive impairment, depression, and social status.

The purpose of the study is to evaluate the indicators of the physical component of quality of life in patients with different types of ischemic stroke, depending on the follow-up, the size of the ischemic lesion, and the severity of the stroke.

Materials and methods. The study included 105 people diagnosed with ischemic stroke in the vertebrobasilar basin. Study groups were formed depending on the follow-up, the type of ischemic stroke, the size of the ischemic lesion, and the severity of the stroke. The SF-36 general questionnaire was used to assess quality of life.

Results. In patients with ischemic stroke, the physical component of health did not depend on catamnesis, but it was probably lower in cardioembolic type of stroke (according to indicators of physical functioning, role functioning and general state of health), in patients with a lesion size >100 cm3 (according to indicators of physical functioning and general state of health), as well as with a severe degree of severity of ischemic stroke at the time of admission (according to indicators of physical functioning, role functioning).

In patients with ischemic stroke, a probable inverse weak strength of association was established between the size of the lesion and physical functioning (r=-0.25; p<0.05), role functioning (r=-0.19; p<0.05) and general health (r=-0.29; p<0.05), as well as between stroke severity on the NIHSS scale and physical functioning (r=-0.34; p<0.05).

Conclusions. The quality of life of patients with ischemic stroke, in particular the physical component of health, is related to the severity of the stroke at admission and the size of the lesion.
CROSS-cultural adaptation and validation of the Ukrainian version of the difficulties in emotional regulation scale (DERS): testing in adolescents with anorexia nervosa and their parents/guardians
Authors: Sak Lesia , Fedotova Zoya
Published: December 2023

Relevance: Emotional dysregulation is often identified in a variety of mental disorders and shows high comorbidity between them. The presence of emotional regulation disorders can be assessed using various tools, but the most popular is the Difficulty in Emotional Regulation Scale (DERS), which is used to assess emotional regulation disorders in different populations, including adults and adolescents, and is widely used both in research and clinical practice. The purpose of the study: to create a Ukrainian-language version of the Difficulties in Emotional Regulation Scale (DERS) and its cross-cultural adaptation among adolescents and adults, with validity assessment and testing in patients with anorexia nervosa and their parents/caregivers.

Methods: The study included 58 adolescents with anorexia nervosa and 97 of their parents/guardians who constituted the main study groups, as well as 50 healthy adolescents and 89 of their parents/guardians as a control group. The full version of the 36-item DERS Emotional Regulation Difficulties Scale was used for validation. The study was conducted in compliance with basic bioethical standards. All patients consented to participate in the study, after which a full clinical examination was conducted: demographic data were collected and screening for emotional regulation disorders was performed using the DERS scale. Statistical analysis was performed using the IBM SPSS23 program.

Results: The analysis of the data obtained showed high reliability and validity of the Ukrainian version of the Difficulties in Emotional Regulation Scale (DERS) for screening emotional regulation disorders. Calculations of the α-Cronbach's coefficient based on the results of the test and retest (14 days later) confirmed the internal consistency of the DERS (0.7 and 0.7, respectively). The intraclass correlation coefficient was 0.976 (p<0.05) for adolescents and 0.987 (p>0.05) for adults. Student's paired t-test did not reveal significant differences between the test-retest groups (p>0.05). Subsequently, a study to validate the DERS scale was conducted on adolescents with anorexia nervosa and their parents/guardians. Our results of the DERS survey showed significantly higher scores on the total DERS score in patients with anorexia nervosa (143.70±11.170) and their parents/guardians (141.85±11. 006) compared to healthy adolescents (54.23±6.01) and their parents/guardians (47.61±7.87) of the control group, p<0.0001, indicating a high level of emotional regulation disorder in patients with anorexia nervosa and their parents/guardians.

Conclusions: The Ukrainian version of the DERS emotional regulation difficulty scale was created and cross-cultural adaptation was performed for further use in the Ukrainian-speaking population. The Ukrainian version of the DERS scale has a sufficient level of reliability that allows it to be used for scientific purposes and in clinical practice.
Visualization of Radiation Scattering Indicatrix on a Polydisperse System of Spherical Particles
Authors: Sapronov M.V. , Usmanova S.S.
Published: December 2023

The article is devoted to solving the direct problem of light scattering on an ensemble of spherical polydisperse particles. The paper presents an algorithm for computer simulation of the optical radiation scattering indicatrix by a particle system based on the theory of G. Mie. The influence of the relative complex refractive index of scattering centers and their size distribution, wavelength and polarization state of incident light on computer models of scattering indicatrix is investigated. The practical significance of the results obtained lies in the fact that computer models of scattering indicatrix are useful in the experimental study of dispersed systems by static light scattering for the optimal choice of installation parameters and experimental conditions and, more importantly, in solving the inverse problem of the static light scattering method to restore the characteristics of nanoparticles from experimental data.
Spectroscopy of Testicular Tissues as a Tool for Azoospermia Visualization During Micro-TESE and IVF: a Feasibility Study
Authors: Yudovskii S.O. , Zolotukhina A.A. , Guryleva A.V. , Machikhin A.S. , Reshetov L.V.
Published: December 2023

Non-obstructive azoospermia observed in 10% of infertile men and 0,6% of all men is the most severe form of male infertility. The histological structure of testicular tissue in patients with non-obstructive azoospermia is heterogeneous and is represented by various disorders of spermatogenesis. The only way to achieve pregnancy in the families of patients with non-obstructive azoospermia is the method of in vitro fertilization with intracellular sperm injection. The most effective method of detecting spermatozoa suitable for in vitro fertilization in testicles is the micro-TESE method. It is based on a subjective visual assessment of tissues and allows detecting spermatozoa in non-obstructive azoospermia only in 38-60% of cases. To increase the effectiveness of micro-TESE, the method used must be objective, high-specific, safe for reproductive cells, and also implemented during the operation in real time. The existing approaches to solving the problem of identifying seminal tubules with preserved spermatogenesis, such as multiphoton microscope, Raman spectroscopy, optical coherence tomography and etc., are either associated with the use of laser radiation with unproven safety or cannot be implemented intraoperatively and operationally. The paper considers the possibility of creating a specialized microsurgical system for intraoperative evaluation of testicular tissues histological structure using the spatial distribution of its spectral characteristics. We proposed to implement such a system based on multispectral imaging of the studied tissues with real-time data processing and displaying the results using augmented reality methods. The reflectance spectrum of testicular tissue with varying degrees of preservation of spermatogenesis in the visible and near infrared spectral ranges was studied. Spectral regions were identified that potentially provide the best differentiation of healthy tissues and tissues with impaired spermatogenesis. The described approach can be implemented intraoperatively and safely and may serve to automate and objectify the diagnosis of testicular tissues in micro-TESE.
Applicability of Visualizations on the Poincare Sphere for The Study of Oscillatory Processes in Photochemical and Photoelectrochemical Systems Including Photoinduced Processes in Semiconductors
Authors: Gradov O.V.
Published: December 2023

The use of visualization on the Poincaré sphere for the analysis of self-organization in semiconductors is quite exotic, however, it does not have physical reasons that would make it impossible to implement this approach. We propose to use the Poincaré sphere visualization method to analyze fluctuations and oscillations in the experimentally measurable concentrations of different ions in self-organizing media, including semiconductors and their precursors under conditions of photoinduced self-organization and microwave-induced self-organization (as well as to analyze the oscillatory impulse wave behavior of their self-organization products in ultrafine form as dispersed semiconductor devices). Approbation of this principle is carried out by means of projection onto the sphere of phase portraits of these types of vibrations, which is equivalent to the implementation of an operator that projects a 2D planar graph onto a 3D sphere.
Explorative Bibliometric Study of Medical Image Analysis: Unveiling Trends and Advancements
Authors: Thomas Binu , Joseph Jeena , Jose Jobin
Published: December 2023

Medical image analysis has quickly advanced, with several advantages for research, diagnosis, and healthcare planning. We must have enough knowledge of current trends and developments in this field due to improvements in medical imaging technology and the accessibility of a wide range of medical image databases. This work covers the research environment for bibliometric analysis of academic articles as part of medical image analysis, utilizing the tools VOSviewer and Biblioshiny. The Scopus database contains 1,973 articles submitted between 1988 and 2023; all have been gathered and examined. The study has focused on the key bibliometric elements, such as authorship patterns, highly cited papers, prestigious journals, and collaborative networks. The outcomes of our inquiry demonstrate its interdisciplinary nature. This bibliometric analysis is a valuable resource for researchers, practitioners, and decision-makers, allowing them to identify significant trends, identify knowledge gaps, and explore prospects for further advancements in this critical field by providing a comprehensive overview of the literature on medical image analysis.
Visualization of a graph model of medical drugs and their classes with subject to incompatibility
Authors: Karandeev A.A. , Iashin N.A. , Kudryashev R.A.
Published: December 2023

Currently, the world is actively undergoing digital transformation, which is associated with the introduction of digital technologies in various fields. Methods for predicting and combating various types of diseases are being developed more and more actively. A separate place in this issue is given to pharmacology and reducing the risks of poly-pharmacotherapy. Works in this area have become more and more active in the last three years, and relate primarily to the problems of experimental medicine - the search for new drugs or classification of patients by images. In this connection, the development of algorithms for processing big data in the field of clinical pharmacology, including regulatory documents, instructions for the use of drugs, reliable medical resources for machine learning and building a knowledge base focused on practical application in real medical practice, is becoming increasingly important.

One of the considered approaches for solving the problems described above is the search for an effective vector representation of the found concepts (word embedding) to build models of recommendations for the practical use of drugs based on the diagnosis and models for identifying their compatibility. The article presents a software tool for visualizing a graph model of medicines and their classes, considering their incompatibility. The problem of incompatibility of medicines is being investigated. The considered database of medicines, obtained from various sources, and the advantages of its use are described. The article presents the results of the developed prototype of a software tool that allows you to visualize a complete graph of relationships between drugs, a graph of incompatible drugs for a selected drug, and a graph of compatibility of two drugs. Graph model visualization provides a visual representation of complex relationships and allows researchers and pharmacologists to better understand interactions between drugs. The software offer the necessary tools to make informed decisions when prescribing medications and improve safety when using medicines.
Application of an Agent-Based Model to Develop Ontological Data Visual Management Tool
Authors: Razdyakonov D.S. , Muromcev D.I.
Published: December 2023

The paper presents an agent-based model of interactive visualization and proposes a method for its application in the development of the ontological data visual management tool. The process of user interaction with the visualization is represented as a state graph, where each node is a separate visualization. The initial state is known, and the final state is formed in the process of user interaction with the ontological data visual management tool. Each intermediate visualization from the state graph is transferred into the multidimensional Euclidean data space formed on the basis of the visualized ontology, which allows to calculate weighting coefficients on the state graph edges and to search the graph using known algorithms. Application of the model allows for a reduction in the labor intensity of executing user scripts due to the reduction of step-by-step visualization creation to the task of searching in the state space.
Data Analysis using Augmented Reality Visualization
Authors: Epifanov M.A. , Pilyugin V.V. , Klimov V.V.
Published: December 2023

In this paper, the authors describe the history of augmented reality and its applicability in scientific visualization and visual analytics. The study explores the benefits of using this technology for analysts studying spatial scenes and presents an advanced online platform for creating augmented reality projects used for educational purposes.
Hysteresis Phenomena in a Liquid Sessile Drop on a Stretchable Inclined Elastic Substrate
Authors: Dekhtyar V.A. , Dubinov A.E.
Published: December 2023

The authors studied states of liquid sessile drops on a stretchable inclined elastic substrate to find out peculiarities of the contact angles hysteresis by digital optical microscopes. The drop elongation and contact angles were recorded on the stages of the band stretching and contraction. An anomalous behavior of the drop was found on the first step of the contraction during which the measured drop parameters remained unchanged. Finally, a new hydrophysical effect was found. It is hysteresis of the drop states, on the background of which the contact angle hysteresis exists.
Evaluating Computer Interactions and Infographics Usability: Analyzing Individual’s Performance through Viewing Patterns
Authors: Alyahya Suzan M.
Published: December 2023

Computer interactions and infographics are important to represent and communicate complex information. The impact of visualization and its effect on learning the results of interaction with multimedia instruction reveals a great deal. Eye tracking is the method used to examine the graphical processing. Therefore, the present study aims to examine computer interactions and infographic usability by conducting verbal and visual performances test on undergraduates. The 62 undergraduate females were recruited as the study sample and presented the video of Napoleon's march to Moscow. This study identifies how long, where, and in what order or when accompanied with text and what’s the participant's pattern on Minard maps. The performance test scores and the verbal visual learning style rating included the visual and verbal variables. The tools that are used to enhance the results are heat maps, cluster and scan paths. The 62 undergraduate females results shows that there is a fundamental difference in verbal and visual learning participants in viewing pattern on the heat map. The heat maps, clusters, and scan paths were combined for the distinct groups to provide a more complete picture of viewing patterns using Tobii Studio Software. The study results indicate that visual content was remembered by most of the participants and also indicated that the visual effects in multimedia learning environments and can be utilized to improve the multimedia design. Therefore, the study concluded that infographic and computer interactions are an effective approach for enhancing the understanding and usability of students.