bluuebunny/crossref_metadata_2025 huggingface dataset:
The Investigation of Challenges in Developing and Implementing New Academic Disciplines in Iranian Universities: Views of the Faculty Members
Authors: Ghazavi Mansuoreh , Nasr Ahmad Reza , Jafari Ebrahim Mirshah , Mosapour Neamatollah
Published: May 2016

The move on decentralization of curriculum development in recent decade has become one of the major tasks in developing scientific fields in Iran. By implementing these programs some drawbacks have become evident. The objective of this study was to identify and assess the existing challenges involved in the development of academic disciplines from the faculty members’ views. For this aim, through a descriptive study, a body of 125 faculty members involved in academic disciplines development from state universities of Isfahan, Tehran and Ferdowsi are randomly selected. The study pursued seven research questions using a researcher-made questionnaire. Findings showed that interdisciplinary challenges, structural challenges and management challenges significantly exceeded the moderate level. Moreover, scientific-professional and financial challenges significantly affected the curriculum development of the academic disciplines. Results of MANOVA further showed that there were significant differences between the mean scores of faculty members’ views regarding the structural and management challenges in different universities. In general, results of the study highlighted the challenges which can be considered as important obstacles in the development process of disciplines and society at large. Optimization of this process needs the correctly addressed opinions of the faculty members in this respect.
Relationship between Optimism, Religiosity and Self-Esteem with Marital Satisfaction and Life Satisfaction
Authors: Homaei Rezvan , Bozorgi Zahra Dasht , Ghahfarokhi Maryam Sadat Mirbabaei , Hosseinpour Shima
Published: May 2016

The purpose of the current study is to investigate the relationship between Optimism, Religiosity and Self-esteem with Marital Satisfaction and Life Satisfaction in married university students. The research method was a descriptive study kind of correlation. The sample group included 200 married students that were selected using a simple random sampling method. For collecting data, Attribution Style Questionnaire, Religious Attitude, Cooper Smith Self-Esteem Questionnaire, Enrich Marital Satisfaction Questionnaire and Satisfaction with Life Scale were used. The findings indicated that marital satisfaction not life satisfaction was predicted by Optimism, Religiosity and Self-esteem. Religiosity showed the greatest relationship with marital satisfaction. Base on this study, family therapists should consider the role of religious or spiritual couple’s attitude as a vital factor in reveal and solving the marital conflict. Consistency and inconsistency of the results were discussed.
Oxygen source-Oriented Control of APCVD VO2 for Capacitive Applications
Authors: Vernardou Dimitra , Bei Antonia , Louloudakis Dimitris , Katsarakis Nikolaos , Koudoumas Emmanouil
Published: May 2016

Vanadium dioxides of different crystalline orientation planes have successfully been fabricated by chemical vapor deposition at atmospheric pressure using propanol, ethanol and O2 gas as oxygen sources. The thick a-axis textured monoclinic vanadium dioxide obtained through propanol presented the best electrochemical response in terms of the highest specific discharge capacity of 459 mAh g-1 with a capacitance retention of 97 % after 1000 scans under constant specific current of 2 A g-1. Finally, the electrochemical impedance spectroscopy indicated that the charge transfer of Li+ through the vanadium dioxide / electrolyte interface was easier for this sample enhancing significantly its capacitance performance.
Role of Tetrasomy for the Diagnosis of Urothelial Carcinoma Using UroVysion Fluorescent In Situ Hybridization
Authors: Zhou Amy G. , Liu Yuxin , Cyr Maryann St. , Garver Joanne , Woda Bruce A. , Cosar Ediz F. , Hutchinson Lloyd M.
Published: May 2016

Context.—UroVysion fluorescent in situ hybridization (FISH) is routinely used to detect urothelial carcinoma (UC). A positive threshold is defined as chromosome polysomy in 4 or more cells, which also includes tetrasomy, a natural product of cell division.

Objectives.—To evaluate tetrasomy for UC detection and explore the relation to the surgical diagnosis or patient history.

Design.—The FISH was performed on 1532 urine samples from patients with cytology results and 4 or more years of follow-up. We created separate polysomy and tetrasomy categories and constructed receiver operating curves to determine appropriate thresholds using biopsy (n = 194) as the gold standard. Standard FISH and a novel assay integrating cytomorphology and FISH (Target-FISH) were compared. Matching tissue biopsies of urine samples with 10 or more tetrasomy cells were analyzed.

Results.—No significant threshold was found for tetrasomy cells. Exclusion of tetrasomy from the polysomy category changed the threshold from 8.5 to 4.5 cells, increased specificity (59.2% to 78.9%), but reduced sensitivity (78.9% to 65.9%). In Target-FISH, the same approach yielded a specificity of 93.7% and sensitivity of 65.2%. Similarly, specificity improved significantly for low- and high-grade UC, but sensitivity decreased for low-grade UC. No evidence of UC was observed in 95% (52 of 55) of the patients referred for screening who had 10 or more tetrasomy cells by FISH. Matching biopsies for urines containing 10 or more tetrasomy cells showed few or no tetrasomy cells.

Conclusions.—Tetrasomy is a nonspecific finding frequently encountered in urine FISH and should be excluded from the polysomy classification. Target-FISH is an optimal approach, offering the ability to detect rare tetrasomy tumors.
Monitoring of the Clonal Fraction by Fluorescence In Situ Hybridization in Myelodysplastic Syndrome: Comparison With International Working Group Treatment Response Criteria
Authors: Park Jae Hyeon , Kim Miyoung , Kong Sun-Young , Yoon Sung-Soo , Lee Dong Soon
Published: May 2016

At the initial diagnosis of myelodysplastic syndrome (MDS) and/or during follow-up, the evaluation of chromosomal abnormalities is based on standard G-banding, whereas the utility of fluorescence in situ hybridization (FISH) is still debated.Context.—

To investigate whether interphase fluorescence in situ hybridization (iFISH) clone size at initial diagnosis of MDS is correlated with survival and whether changes in clonal fraction by iFISH are concordant with the MDS International Working Group response criteria during follow-up.Objectives.—

A tailored FISH panel (−5/5q−, −7/7q−, +8, −20/20q−, and +1/1q+), based on reported cytogenetic changes in Korean patients with MDS, was performed in 81 patients with MDS at initial diagnosis and in 28 patients during follow-up.Design.—

During follow-up, absolute increases in the clone size by iFISH by 20% or more, with relative increases of 50% or more, compared with previous specimens, were associated with transformation to acute myeloid leukemia (P = .001 and P = .002, respectively). Of the 28 patients with abnormal iFISH results, 7 (25%) showed discordance between iFISH and MDS International Working Group responses. Concordance between clone size by G-banding and iFISH was higher in the refractory cytopenia with unilineage dysplasia/refractory cytopenia with multilineage dysplasia group during follow-up, whereas the group with refractory anemia with excess blasts showed higher correlation at initial diagnosis.Results.—

We conclude that iFISH can provide additional prognostic information and can predict the response to therapy in MDS.Conclusions.—
Clinicopathologic Threshold of Acute Colorectal Graft-versus-Host Disease
Authors: Gomez Adam J. , Arai Sally , Higgins John P. , Kambham Neeraja
Published: May 2016

Colon biopsies are often used to determine the presence and severity of acute gastrointestinal graft-versus-host disease following bone marrow transplant.Context.—

To establish a threshold consensus within our institution on the number of crypt apoptotic bodies (CAB) indicative of grade 1 acute colorectal graft-versus-host disease, we retrospectively reviewed colon biopsies from posttransplant patients and incorporated clinical and endoscopic findings to validate recently proposed minimum criteria for grade 1 graft-versus-host disease as 7 or more CAB per 10 contiguous crypts.Objective.—

Eighty-one biopsies performed for suspected graft-versus-host disease from 74 individual patients were initially stratified based on their prior (prestudy) diagnoses: no significant abnormality, grade 1 graft-versus-host disease, and descriptive diagnoses mentioning increased apoptosis. A chart review was performed to assess the clinical and endoscopic impression at the time of biopsy and to determine the subsequent management and outcome.Design.—

Twenty-six biopsies with an average of 3 CAB were considered true-negative cases, and 32 biopsies with an average of 9.75 CAB were considered true-positive cases (t = 3.95999, P < .001). True-negative cases had an average density of 1.36 CAB per crypt, and true-positive cases had an average density of 2.97 CAB per crypt (t = 3.950178, P < .001).Results.—

A threshold of 7 or more CAB per 10 contiguous crypts promotes appropriate treatment of grade 1 acute graft-versus-host disease after other diagnostic entities are excluded. Although this threshold is 100% specific to grade 1 acute colorectal graft-versus-host disease after other histologic mimics are excluded, this threshold has a low sensitivity (59.4%) as patients with less than 7 CAB per 10 contiguous crypts constitute a heterogeneous group.Conclusions.—
Can we help in changing the future of Italian health care?
Authors: Di Napoli Mario
Published: May 2016

[The abstract of this article is not available. Here are the first sentences of the article. The full text is freely available upon registration]The retirement age of the baby boom generation is almost out-door. The proportion of ageing people will grow rapidly in the near future [1-3]. There will be fewer people to pay for the health and social care of the quickly aging population; furthermore, advancements in medical science will raise a new bar for quality in terms of the outcomes achieved in the treatment of illness [3]. An ageing population and the rising public expectations will produce an increase in costs and will impede timely access to care, thus jeopardising sustainability.The Italian National Health system is an example of a collapsing system: the ageing Italian workforce affects not only patient demographics but also the availability of clinicians. The upcoming wave of retiring health care professionals will occur in the exact moment when they will be more necessary. To overcome these challenges, our health care system will have to use its resources more effectively. Access and equity remain essential characteristics of our health care system, but are insufficient goals in terms of improving quality and achieving financial sustainability.
The intracerebral haemorrhage associated to oral anticoagulant therapy: the practical management of urgent reversal therapy
Authors: Masotti Luca , Di Napoli Mario , Godoy Daniel , Rafanelli Daniela , Liumbruno Giancarlo , Prisco Domenico , Poli Daniela , Landini Giancarlo , Koumpouros Nicholas , Pennati Paolo , Pampana Alessandro , Cappelli Roberto
Published: May 2016

Intracerebral haemorrhage (ICH) represents the most feared complication of therapy with vitamin K antagonists (VKA), so-called oral anticoagulant therapy (OAT). This is a real emergency in clinical practice, being burdened by high mortality, morbidity and residual functional disability. In recent years, there have been widespread indications for the correct management of VKA associated ICH. The urgent OAT reversal represents the cornerstone of VKA associated ICH therapy. The knowledge of these guidelines is of fundamental importance in clinical practice. The urgent OAT reversal could stop the hematoma enlargement which is considered one of the main risk factor of poor outcome in this clinical setting. The aim of urgent OAT reversal is bringing the INR (International Normalized Ratio) to values ≤ 1.4. It is possible by using prothrombin complex concentrate (PCC), fresh frozen plasma (FFP), recombinant activated factor VII (raFVII) together with vitamin K1 intravenous infusion. In this article the Authors review the practical management of urgent OAT reversal in patients suffering for VKA related ICH.
Chronic obstructive pulmonary disease and comorbidity: possible implications in the disease management
Authors: Paggiaro Pierluigi , Costa Francesco , Malagrinò Laura , Vagaggini Barbara
Published: May 2016

Chronic obstructive pulmonary disease (COPD) is becoming the first cause of pulmonary disability and death. Because of the increase in the mean age of the population, COPD is frequently associated with important comorbidities that require medical attention. In the last 10 years many observational studies (large surveys of population or databases of the main health organisations or of General Practitioners in different Countries) have extensively documented that many diseases (cardiovascular diseases, metabolic syndrome, osteoporosis, diabetes, depression, and lung cancer) have a higher prevalence in COPD patients than in non-COPD ones (after correction for many confounding factors, such as smoking habit). There are two different views relating the association between COPD and comorbidities. These comorbidities may be just randomly associated with COPD (due to common risk factors including age), but many data support the hypothesis that chronic inflammation derived from airway wall and lung parenchima of COPD patients may “spill over” the systemic circulation and mediate, at least partially, negative effects on other organs or systems. Some comorbidities seem more commonly associated with the functional abnormalities of COPD (like skeletal muscle dysfunction and malnutrition, or osteoporosis, which are related to the inactivity due to dyspnoea), while for others the systemic effect of some cytokines (IL-6,TNFalfa, etc.) or mediators (CRP, serum amyloid A, etc.) may play a role.Since comorbidities represent major causes of death in COPD patients, and are responsible of poorer quality of life and hospitalisation during COPD exacerbations, their presence requires a new approach, including an interdisciplinary co-operation and the use of specific strategies able to affect the several pulmonary and extra-pulmonary components of the disease. New pharmacologic options (such as roflumilast) active on both pulmonary and extra-pulmonary inflammation might be useful in the future.
Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling
Authors: Raj Anil , Wang Sidney H , Shim Heejung , Harpak Arbel , Li Yang I , Engelmann Brett , Stephens Matthew , Gilad Yoav , Pritchard Jonathan K
Published: May 2016

Accurate annotation of protein coding regions is essential for understanding how genetic information is translated into function. We describe riboHMM, a new method that uses ribosome footprint data to accurately infer translated sequences. Applying riboHMM to human lymphoblastoid cell lines, we identified 7273 novel coding sequences, including 2442 translated upstream open reading frames. We observed an enrichment of footprints at inferred initiation sites after drug-induced arrest of translation initiation, validating many of the novel coding sequences. The novel proteins exhibit significant selective constraint in the inferred reading frames, suggesting that many are functional. Moreover, ~40% of bicistronic transcripts showed negative correlation in the translation levels of their two coding sequences, suggesting a potential regulatory role for these novel regions. Despite known limitations of mass spectrometry to detect protein expressed at low level, we estimated a 14% validation rate. Our work significantly expands the set of known coding regions in humans.
Predictive lethal proarrhythmic risk evaluation using a closed-loop-circuit cell network with human induced pluripotent stem cells derived cardiomyocytes
Authors: Nomura Fumimasa , Hattori Akihiro , Terazono Hideyuki , Kim Hyonchol , Odaka Masao , Sugio Yoshihiro , Yasuda Kenji
Published: May 2016

For the prediction of lethal arrhythmia occurrence caused by abnormality of cell-to-cell conduction, we have developed a next-generation in vitro cell-to-cell conduction assay, i.e., a quasi in vivo assay, in which the change in spatial cell-to-cell conduction is quantitatively evaluated from the change in waveforms of the convoluted electrophysiological signals from lined-up cardiomyocytes on a single closed loop of a microelectrode of 1 mm diameter and 20 µm width in a cultivation chip. To evaluate the importance of the closed-loop arrangement of cardiomyocytes for prediction, we compared the change in waveforms of convoluted signals of the responses in the closed-loop circuit arrangement with that of the response of cardiomyocyte clusters using a typical human ether a go-go related gene (hERG) ion channel blocker, E-4031. The results showed that (1) waveform prolongation and fluctuation both in the closed loops and clusters increased depending on the E-4031 concentration increase. However, (2) only the waveform signals in closed loops showed an apparent temporal change in waveforms from ventricular tachycardia (VT) to ventricular fibrillation (VF), which is similar to the most typical cell-to-cell conductance abnormality. The results indicated the usefulness of convoluted waveform signals of a closed-loop cell network for acquiring reproducible results acquisition and more detailed temporal information on cell-to-cell conduction.
Sonography for Complete Evaluation of Neonatal Intensive Care Unit Central Support Devices
Authors: Saul David , Ajayi Samuel , Schutzman David L. , Horrow Mindy M.
Published: May 2016

Objectives

Neonates in the neonatal intensive care unit often require considerable support with endotracheal tubes, umbilical arterial and venous catheters, and peripherally inserted central venous catheters. Support device evaluation with radiography exposes neonates to ionizing radiation. This study evaluated the effectiveness of sonographic localization for endotracheal tubes, umbilical arterial and venous catheters, and peripherally inserted central venous catheters.

Methods

This blinded prospective Institutional Review Board–approved, Health Insurance Portability and Accountability Act–compliant study with informed consent compared sonography to radiography for endotracheal tube, umbilical arterial and venous catheter, and peripherally inserted central venous catheter localization. Participants were consecutively recruited NICU patients of any weight, gestation, and chronologic age who had an endotracheal tube, umbilical arterial catheter, umbilical venous catheter, or peripherally inserted central venous catheter placed or adjusted and had subsequent radiographic confirmation within 24 hours. Sonographic evaluation was obtained as soon as possible, without prior review of the radiograph, and results were compared.

Results

Thirty sonographic studies were performed in 25 patients (14 male and 11 female), for a total of 50 lines and tubes: 18 umbilical venous catheters, 12 umbilical arterial catheters, 11 peripherally inserted central venous catheters, and 9 endotracheal tubes. Forty‐nine support devices (98%) were visualized with sonography, all concordant with radiography. Forty‐four were correctly positioned, and 6 were malpositioned. Sonography identified the location of umbilical venous catheters in all 18 cases (100%), umbilical arterial catheters in all 12 (100%), peripherally inserted central venous catheters in 10 (91%), and endotracheal tubes in 9 (100%).

Conclusions

The effectiveness of sonography was excellent for evaluation of umbilical arterial and venous catheters, endotracheal tubes, and peripherally inserted central venous catheters. These results support the goal of further point‐of‐care training and accreditation to use sonography as a primary modality for complete evaluation of NICU support devices.
Quantifying mesoscale eddies in the Lofoten Basin
Authors: Raj R. P. , Johannessen J. A. , Eldevik T. , Nilsen J. E. Ø. , Halo I.
Published: May 2016

The Lofoten Basin is the most eddy rich region in the Norwegian Sea. In this paper, the characteristics of these eddies are investigated from a comprehensive database of nearly two decades of satellite altimeter data (1995–2013) together with Argo profiling floats and surface drifter data. An automated method identified 1695/1666 individual anticyclonic/cyclonic eddies in the Lofoten Basin from more than 10,000 altimeter‐based eddy observations. The eddies are found to be predominantly generated and residing locally. The spatial distributions of lifetime, occurrence, generation sites, size, intensity, and drift of the eddies are studied in detail. The anticyclonic eddies in the Lofoten Basin are the most long‐lived eddies (>60 days), especially in the western part of the basin. We reveal two hotspots of eddy occurrence on either side of the Lofoten Basin. Furthermore, we infer a cyclonic drift of eddies in the western Lofoten Basin. Barotropic energy conversion rates reveals energy transfer from the slope current to the eddies during winter. An automated colocation of surface drifters trapped inside the altimeter‐based eddies are used to corroborate the orbital speed of the anticyclonic and cyclonic eddies. Moreover, the vertical structure of the altimeter‐based eddies is examined using colocated Argo profiling float profiles. Combination of altimetry, Argo floats, and surface drifter data is therefore considered to be a promising observation‐based approach for further studies of the role of eddies in transport of heat and biomass from the slope current to the Lofoten Basin.
ChemInform Abstract: Ab initio Molecular Orbital Calculations on LiPO2 and LiClO2 Charge‐Transfer Complexes: Geometries and Vibrational Frequencies.
Authors: RAMONDO F. , BENCIVENNI L.
Published: May 2016

HF‐SCF calculations for the ions PO2‐ and ClO2‐ and for LiPO2 and LiClO2 indicate that the association of PO2‐ and ClO2‐ with Li atoms (bidendate or monodentate) depends on the position of the metal with respect to the anionic group.
ChemInform Abstract: Hyperfine Field Anisotropy and Spin Reorientation in Ternary Carbides of the Type Ln2Fe17Cx.
Authors: GUBBENS P. C. M. , VAN DER KRAAN A. M. , JACOBS T. H. , BUSCHOW K. H. J.
Published: May 2016

Sm2Fe17Cx (I) and Er2Fe17Cx (II) are studied by 57Fe Moessbauer spectroscopy.
ChemInform Abstract: Porous Silicon Oxide Layer Formation by the Electrochemical Treatment of a Porous Silicon Layer.
Authors: YAMANA M. , KASHIWAZAKI N. , KINOSHITA A. , NAKANO T. , YAMAMOTO M. , WALTON C. W.
Published: May 2016

A porous silicon oxide structure with pores of 0.5‐2 μm diameter is obtained by cathodic treatment of a porous silicon layer (PSL, pore sizes in the range 40‐200 Å) in aqueous KCl.
ChemInform Abstract: Reactions of Trifluoromethyl Bromide and Related Halides. Part 10. Perfluoroalkylation of Aromatic Compounds Induced by Sulfur Dioxide Radical Anion Precursors.
Authors: TORDEUX M. , LANGLOIS B. , WAKSELMAN C.
Published: May 2016

A series of aromatic compounds, e.g. benzene, toluene (I), anilines, phenols, and heteroaromatic compounds, e.g. pyrroles, pyridine (VI) and methylpyridines (total ca. 35 examples) is trifluoromethylated by two different methods.
ChemInform Abstract: Reactions of a Tetrasubstituted Thiocarbonyl Ylide. New Evidence for Two‐Step Cycloadditions.
Authors: HUISGEN R. , MLOSTON G.
Published: May 2016

The tetramethylthioxocyclobutanone (I) reacts with 2‐diazopropane (II) in pentane to give the 1,3,4‐thiadiazoline (III) which is converted into the vinyl thioether (VI) and the thioacetal (VIII) upon treatment with methanol (VII).
ChemInform Abstract: CO2 Laser Induced Chain Reaction of C2F4 + CF3I.
Authors: GONG M. , FUSS W. , KOMPA K. L.
Published: May 2016

To avoid undesired dimerization of initial radicals, the telomerization of (I) and (II) is carried out at high pressure (up to 3 bar) leading to small instantaneous concentration.
ChemInform Abstract: Making a Vinyltrimethylenemethane Precursor Through the Addition of Diethyl Azodicarboxylate to Tropone.
Authors: BUSHBY R. , JARECKI C.
Published: May 2016

The diazabicyclononadiene (XI) is prepared via a 7‐step process from tropone (I) and diethyl azodicarboxylate (II).
ChemInform Abstract: Studies in (3,4) Sigmatropic Rearrangements: A Novel Synthesis of 9‐Allenyl‐10‐Substituted Anthracenes from 10,10‐Disubstituted 9‐Anthrols.
Authors: MAJUMDAR K. C. , KHAN A. T. , CHATTOPADHYAY S. K.
Published: May 2016

Derivatives such as (IIa) and (IIb) rearrange to the title compounds (III) by a transannular migration of the propynyl group.
ChemInform Abstract: Synthesis of Fluorantheno(1,2‐b)thiophene and Fluorantheno(3,2‐b)thiophene, Isosteres of Benzofluoranthenes.
Authors: LEE‐RUFF E. , CHUNG Y. S.
Published: May 2016

The cyclobutanone (III) serves as the common intermediate for the preparation of the title compounds (IV) and (V).
ChemInform Abstract: Synthesis of 4,4‐Disubstituted 2,3‐Dicyano‐5‐imino‐2‐pyrrolines. Reaction of Akylidenemalononitriles with Trimethylsilyl Cyanide.
Authors: CHATANI N. , HANAFUSA T.
Published: May 2016

The title compounds (III) are useful intermediates for organic synthesis because of their multifunctionalities.
ChemInform Abstract: Organic Nitrosonium Salts. Part 2. Stability Studies and Oxidations of Some Indole Derivatives.
Authors: BOBBITT J. M. , GUTTERMUTH M. C. F. , MA Z. , TANG H.
Published: May 2016

Electrolysis of the tetramethylpiperidinyl‐1‐oxyl (I) with lithium tetrafluoroborate (II) yields the tetramethylpiperidine‐1‐oxonium tetrafluoroborate (III) which is also prepared from (I) by disproportionation reaction with tetrafluoroboric acid (IV).
ChemInform Abstract: Potential Antitumor Agents. Part 4. Pyrrole Analogues of Oncodazole.
Authors: MASSA S. , DI SANTO R. , ARTICO M.
Published: May 2016

The title compounds (V) and (XI) are prepared in order to test their biological activity.
ChemInform Abstract: The Synthesis of 3,5‐Bis(trifluoromethyl)‐4H‐1,2,4‐triazole and Some 1‐and 4‐Substituted Derivatives from 2,5‐Dichloro‐1,1,1,6,6,6‐hexafluoro‐3,4‐diazahexa‐2,4‐diene.
Authors: ABDUL‐GHANI M. , TIPPING A. E.
Published: May 2016

Starting with the title azine (I), the triazolate (IV) and the triazole (XIV) are formed by thermal cyclization.
ChemInform Abstract: Reduction of N‐Oxides with Bakers′ Yeast.
Authors: TAKESHITA M. , YOSHIDA S.
Published: May 2016

Treatment of the pyridine N‐oxides (I) with bakers' yeast in water results in deoxygenation to give the pyridines (II).
ChemInform Abstract: Synthesis of Isoxazolo(2,3‐a)quinoxalines and Pyrrolo(1,2‐a)quinoxalines by 1,3‐Dipolar Cycloaddition Reaction.
Authors: KIM H. S. , KURASAWA Y. , YOSHII C. , MASUYAMA M. , TAKADA A. , OKAMOTO Y.
Published: May 2016

Depending on the conditions the title reaction of the N‐oxide (I) with the ester (II) yields the fused isoxazoles (III) or the fused pyrroles (IV).
ChemInform Abstract: Organometallics in Carbon‐Carbon Bond Formation in 1,2,6‐Thiadiazine 1,1‐Dioxides.
Authors: RHODE WANG L. R. , BENNECHE T. , UNDHEIM K.
Published: May 2016

Halogenated thiadiazine dioxides such as (V) or (IX) are prepared starting from the readily available heterocycle (I).
ChemInform Abstract: Torand Synthesis by Trimerization ‐ New Receptors for Guanidinium.
Authors: BELL T. W. , LIU J.
Published: May 2016

The largest cycloarene derivative reported so far, i.e. the new torand (VIII), is surprisingly readily accessible by CsOH‐mediated cyclotrimerization starting from the aldehyde (IV).
ChemInform Abstract: Synthesis of Novel 1H‐Imidazo(5,1‐b)(3)benzazepine‐1,3(2H)‐dione and Pyrimido(6,1‐b)(3)benzazepine‐1,3,4(2H)‐trione.
Authors: GALLASCHUN R. J. , SCHNUR R. C.
Published: May 2016

The novel tricyclic ring system (IV) is obtained by an unusual Stiles reaction of the benzazepines (I).
ChemInform Abstract: Phosphorylation of N‐Acetylthiourea with Phosphorus Pentachloride.
Authors: ROZINOV V. G. , DMITRICHENKO M. YU. , DOLGUSHIN G. V. , DONSKIKH V. I.
Published: May 2016

N‐Acetylthiourea (I) reacts with phosphorus pentachloride (II) to give the phosphoramidic dichloride (III) which is dehydrohalogenated upon heating to produce the compound (IV).
ChemInform Abstract: N‐ and S‐Phosphorylated Ketene S,N‐Acetals.
Authors: ZHELTOVA E. V. , CHURUSOVA S. G. , KOZLOV V. A. , GRAPOV A. F. , MEL'NIKOV N. N.
Published: May 2016

The malononitriles (I) or (IV) are coupled with potassium O,O‐diethyl dithiophosphate (II) or O,O‐diethyl dithiophosphate (V) to give the ketene S,N‐acetals (III) and (VI) respectively.
ChemInform Abstract: A Phosphaalkene Stabilized by a C‐Carboranyl Group.
Authors: MARKOVSKII L. N. , ROMANENKO V. D. , RUBAN A. V. , SARINA T. V. , OL'SHEVSKAYA V. A. , ZAKHARKIN L. I.
Published: May 2016

Treatment of m‐carborane‐1‐carboxylic chloride (I) with tris(trimethylsilyl)phosphine (II) gives the phosphaalkene (IV) via the bissilyl(carboranylcarbonyl)phosphine (III).
ChemInform Abstract: Protonation of Alkylidyne(carbaborane)tungsten Complexes: Framework Rearrangement of an Icosahedral Cage at an Unprecedentedly Low Temperature.
Authors: BREW S. A. , JEFFERY J. C. , PILOTTI M. U. , STONE F. G. A.
Published: May 2016

The alkylidyne tungstacarborane anion (I) exhibits a novel chemistry.
ChemInform Abstract: Structure and Reactivity of Cp2W(η2‐Me2Si=CH2), a Tungsten Silene Complex.
Authors: KOLOSKI T. S. , CARROLL P. J. , BERRY D. H.
Published: May 2016

The title complex (II) (space group P212121, Z=4) obtained by reductive dechlorination is characterized by X‐ray structure analysis, NMR spectra, and reactions.
ChemInform Abstract: Optically Active Transition‐Metal Complexes. Part 99. Optically Active Phosphido‐Bridged Molybdenum, Rhodium, and Iron Complexes.
Authors: BRUNNER H. , PETER H.
Published: May 2016

The phosphido‐bridged complexes (III), (VI), (VII), and (VIII) are obtained starting with the optically active phospholanes (V), its Li derivatives or the diphosphane (II) and corresponding metal compounds.
ChemInform Abstract: Preparation of Sulfur Ylide Complexes of Platinum by Phase Transfer Catalysis.
Authors: LAI J. S. , WU R. F. , LIN I. J. B. , CHENG M. C. , WANG Y.
Published: May 2016

Pt complexes such as (I) react with trimethylsulfoxonium iodide (II) to give complexes such as (III), which contain a bidentate double sulfur ylide as confirmed by an X‐ray analysis of (IIIa) (space group Pna21, Z=4).
ChemInform Abstract: Potent, Broad‐Spectrum Inhibition of Glycosidases by an Amidine Derivative of D‐Glucose.
Authors: TONG M. K. , PAPANDREOU G. , GANEM B.
Published: May 2016

The amidine analogue of D‐glucose, i.e. (IV)·HCl, combines the correct charge and conformation of the glucosyl cation (considered to be an important intermediate in enzymatic glycoside cleavage).
ChemInform Abstract: A Mild and Rapid 1,2‐trans‐Glycosidation Method via Benzoyl‐Protected Glycopyranosyl P,P‐Diphenyl‐N‐(p‐toluenesulfonyl)phosphinimidates.
Authors: HASHIMOTO S. , HONDA T. , IKEGAMI S.
Published: May 2016

The benzoyl‐protected glycopyranosyl phosphinimidate (I) reacts with the alcohols (II) in the presence of boron trifluoride etherate to produce the ethers (III).
ChemInform Abstract: 2‐(Heteroatom‐Substituted)methyl Penems. Part 4. Oxygen Derivatives.
Authors: ALPEGIANI M. , BEDESCHI A. , GIUDICI F. , PERRONE E. , VISENTIN G. , ZARINI F. , FRANCESCHI G.
Published: May 2016

Reaction of the penem (I) with the carboxylic acids (II) yields the 2‐(acyloxymethyl) penems (III).
ChemInform Abstract: Crystal Structure and Vibrational Spectra of Na2VO(SO4)2.
Authors: FEHRMANN R. , BOGHOSIAN S. , PAPATHEODOROU G. N. , NIELSEN K. , BERG R. W. , BJERRUM N. J.
Published: May 2016

Blue needle‐shaped single crystals of the title compound are prepared by bubbling a 10% SO2‐90% N2 gas mixture through a melt of Na2S2O7 containing V2O5 (400 °C).
ChemInform Abstract: The Role of Polyvalent Cations in Developing Strong Acidity: A Study of Lanthanum‐Exchanged Zeolites.
Authors: CARVAJAL R. , CHU P.‐J. , LUNSFORD J. H.
Published: May 2016

La3+ ions are introduced (ion‐exchange) into a series of faujasite and ZSM‐20 zeolites having a minimum amount of extraframework Al and a broad range of Si/Al ratios and the catalytic activity of the resulting materials in the hexane cracking reaction is measured.
ChemInform Abstract: Chiral Recognition in the Reaction of the Enolate Derived from ((η5‐C5H5)Fe(CO)(PPh3)COCH2OCH2Ph) with 1‐Phenylethyl Bromide.
Authors: DAVIES S. G. , MIDDLEMISS D. , NAYLOR A. , WILLS M.
Published: May 2016

The racemic phenylethyl bromide (IV) reacts with the racemic lithium enolate (III) under chiral recognition to produce the diastereoisomerically pure iron acyl complex (V) which is oxidatively demetalated, yielding the dibenzyl acetal (VI).
ChemInform Abstract: Regio‐ and Stereoselectivity in Uncatalysed and Catalysed Diels‐Alder Reactions of Allenic Esters with Furan and 2‐Methylfuran.
Authors: ISHAR M. P. S. , WALI A. , GANDHI R. P.
Published: May 2016

It is shown, that only the C(2)‐C(3) π‐bond of allenic esters such as (II) is involved in Diels‐Alder reactions.
ChemInform Abstract: The Action of Sodium Hydrogen Telluride on Olefins.
Authors: BARTON D. H. R. , BOHE L. , LUSINCHI X.
Published: May 2016

The action of NaTeH on non‐electrophilic C=C bonds is investigated.
ChemInform Abstract: Desulfurization of Benzothiophene Derivatives with Nickel Boride.
Authors: BACK T. G. , YANG K.
Published: May 2016

The sulfur compounds (I), (III), and (V) are desulfurized with nickel boride, generated in situ from nickel chloride hexahydrate and sodium borohydride, to produce undecane (II), naphthalene (IV), or the alkylbenzenes (VI).
ChemInform Abstract: C‐Alkylation of β‐Diketones with Benzylpyridinium Salts. Evidence for Chain Radical Mechanisms.
Authors: MARQUET J. , MORENO‐MANAS M. , PACHECO P. , PRAT M. , KATRITZKY A. R. , BRYCKI B.
Published: May 2016

The para‐substituted benzyltriphenylpyridinium cations (I) react with the β‐diketones (II) by mechanisms which depend on the para‐substituent.
ChemInform Abstract: Stereodivergent Synthesis of 1,2‐Diol Derivatives via α‐Alkoxy Organolead Compounds. SE2‐Retention Pathway.
Authors: YAMADA J. , ABE H. , YAMAMOTO Y.
Published: May 2016

For the first time the preparation of alkoxy organolead compounds such as (I) and (V) and their stereodivergent and enantioselective transformation into syn‐ or anti‐diols is described.
ChemInform Abstract: Asymmetric Synthesis of (R)‐Muscone by Enantioselective Addition of Chiral Methylcuprate to E‐2‐Cyclopentadecen‐1‐one.
Authors: TANAKA K. , USHIO H. , SUZUKI H.
Published: May 2016

E‐2‐Cyclopentadecen‐1‐one (I) reacts with lithium dimethylcuprate (II) in the presence of a chiral ligand such as TATH to yield (R)‐muscone (III).
ChemInform Abstract: C‐H Bond Activation of Aldimine by Rh(I): New Synthesis of β,γ‐Unsaturated Ketone from Aldehyde Through Iminoacylrhodium(III)‐η3‐allyl Complexes.
Authors: JUN C.‐H.
Published: May 2016

The synthesis of the β,γ‐unsaturated ketones (VIII) according to the scheme demonstrates that it is possible to synthesize these ketones from the aldehyde PhCHO by C‐H bond activation of aldimine (III), a subsequent hydride addition into coordinated diolefins, and hydrolysis of the β,γ‐unsaturated ketimine (VII) formed from the reductive elimination of iminoacyl‐Rh(III)‐η3‐allyl complexes (VI).
ChemInform Abstract: Sulfur Ylides. Part 3. Synthesis of Amino Group‐Containing Sulfur Ylides Stabilized by Keto Groups from Amino Acids.
Authors: TOLSTIKOV G. A. , GALIN F. Z. , LAKEEV S. N. , KHALILOV L. M. , SULTANOVA V. S.
Published: May 2016

Starting with the carboxylic chlorides (I), the S‐ylides (VI) are prepared via the bromo ketones (III) and the sulfonium salts (V).
ChemInform Abstract: A Convenient Synthesis of 2‐(1‐Hydroperoxyalkyl)furan Derivatives.
Authors: ANTONIOLETTI R. , BONADIES F. , FLORO C. , SCETTRI A.
Published: May 2016

The by‐products (III) from the oxidation of the alkylidenefurans (I) leading to the title compounds (II) are likewise obtained by reduction of (II).
ChemInform Abstract: Synthesis and Antiviral Activity of 3‐Nitro‐5‐hydroxybenzofuran Derivatives.
Authors: LYUBCHANSKAYA V. M. , BOGDANOVA G. A. , NIKOLAYEVA I. S. , IL'INA M. G. , FOMINA A. N. , GRANIK V. G.
Published: May 2016

Condensation reaction of the benzofurans (I) with the amide acetals (II) produces the benzofuranyl enamines (III) of which (IIIb) is further converted as shown in the reaction scheme.
ChemInform Abstract: Specific Inhibition of Benzodiazepine Receptor Binding by Some N‐(2‐Methyl‐ or 1,2‐Dimethylindol‐3‐ylglyoxyloyl)amino Acid Derivatives.
Authors: PRIMOFIORE G. , MARINI A. M. , DA SETTIMO F. , SALVADORI C. , MARTINI C. , LUCACCHINI A. , GIANNACCINI G.
Published: May 2016

The indoles (I) react with oxalyl chloride (II) in the presence of the amino acid esters (III) to give the (indolylglyoxyloyl)amino acid esters (IV).
ChemInform Abstract: Synthesis of 2,4‐Dihydropyrrolo(3,4‐b)pyrroles and 4,6‐Dihydro‐2H‐dipyrrolo(3,4‐b:3′,4′‐d)pyrroles.
Authors: SHA C.‐K. , LIU J.‐M. , CHIANG R.‐K. , WANG S.‐L.
Published: May 2016

The azidomethylpyrrolylmethylenepropanedioate (IX), prepared from the pyrrolethiocarboxylate (I) as outlined in the reaction scheme, is cyclized upon treatment with triphenylphosphine to produce the arylsulfonyldihydropyrrolo(3,4‐b)pyrrole (X).
ChemInform Abstract: TeCl4‐Mediated Reaction of β‐Keto Nitroalkanes with Activated Olefins. Formation of 3‐Acyl‐2‐isoxazolines.
Authors: SUZUKI H. , SHIMIZU H. , INAMASU T. , TANI H. , TAMURA R.
Published: May 2016

The nitro ketone (Ia) reacts with TeCl4 to give the hydroximoyl chloride (II).
ChemInform Abstract: Regioselectivity in the 3,5‐Dialkylation of 3,5‐Dimethyl‐4‐(4‐methylcyclohexen‐1‐yl)isoxazole.
Authors: POLO C. , RAMOS V. , TORROBA T. , BOSSIO R. , MARCACCINI S. , PEPINO R.
Published: May 2016

The lithium salt of the dimethyl(methylcyclohexenyl)isoxazole (I) reacts with β‐methallyl chloride (II) in tetrahydrofuran to yield a mixture of the homoallyl derivatives (III) ‐ (V).
ChemInform Abstract: Synthesis of Some 1,3,4‐Oxa‐ and 1,3,4‐Thiadiazole Derivatives.
Authors: MANSOUR E.‐S. M. E. , KASSEM A. A. , EL‐ARABI M. E. , NASSER M. A. , EL‐TOUKHY A. A.
Published: May 2016

Condensation of benzoyl chloride (I) with S‐methyl hydrazinecarbodithioate (II) produces the benzoyl dithioate (III) which is cyclized to form the 1,3,4‐thiadiazole (IV) or the 1,3,4‐oxadiazole (V) upon reaction with phosphorus pentoxide or thionyl chloride respectively.
ChemInform Abstract: New Quinoline Derivatives: Synthesis and Evaluation for Antiinflammatory and Analgesic Properties. Part 1.
Authors: PELLERANO C. , SAVINI L. , MASSARELLI P. , BRUNI G. , FIASCHI A. I.
Published: May 2016

The 4‐chloroquinolinecarboxylates (I) are coupled with anilines such as (II) and (V) to produce the 4‐anilinoquinoxalinecarboxylates (III) and (VI).
ChemInform Abstract: Synthesis and Antitumor Activity of 1‐(((Dialkylamino)alkyl)amino)‐4‐methyl‐5H‐pyrido(4,3‐b)benzo(e)‐ and ‐benzo(g)indoles. A New Class of Antineoplastic Agents.
Authors: NGUYEN C. H. , LHOSTE J.‐M. , LAVELLE F. , BISSERY M.‐C. , BISAGNI E.
Published: May 2016

Condensation reaction of the tetralones (I) with the hydrazine (II) gives the hydrazones (III).
ChemInform Abstract: Azadiboriridine‐Borane: A Non‐Classical Acid‐Base Adduct.
Authors: PAETZOLD P. , REDENZ‐STORMANNS B. , BOESE R. , BUEHL M. + , VON RAGUE SCHLEYER P.
Published: May 2016

Treating the azadiboriridine (Ia) with the Lewis acid (II) surprisingly leads to the novel bicyclobutane derivative (IIIa) (space group P21/n, Z=4) which is characterized by NMR studies and X‐ray structure analysis.
ChemInform Abstract: 1,4,6‐Tris(diisopropylamino)‐1,4,6‐triboraspiro(4.4)nona‐2,8‐diene from the Reaction of Benzene with Subvalent Boron Species.
Authors: MELLER A. , BROMM D. , MARINGGELE W. , HEINE A. , STALKE D. , SHELDRICK G. M.
Published: May 2016

Consecutive treatment of benzene (I) with sodium potassium alloy and the dichloroaminoborane (II) produces the triboraspirononadiene (III).
ChemInform Abstract: Formation of Silylated iso‐Pentaphosphanes.
Authors: FRITZ G. , VAAHS T. , JARMER M.
Published: May 2016

Reactions aiming on the formation of partly silylated iso‐pentaphosphanes are reported.
ChemInform Abstract: The iso‐Tetraphosphane P(P(SiMe3)(C6H5))3.
Authors: FRITZ G. , JARMER M. , MATERN E.
Published: May 2016

The preparation of the title compound (III) from PCl3 (I) and the Li phosphide (II) requires two steps: at ‐78 °C PCl3 (I) reacts with two equiv. (II) without side reactions; at ‐35 °C the formed intermediate (Ph(Tms)P)2PCl reacts with the third phosphide (II) to yield (III) quite cleanly.
ChemInform Abstract: A Compound with a Boron‐Arsen Double Bond.
Authors: PETRIE M. A. , SHONER S. C. , DIAS H. V. R. , POWER P. P.
Published: May 2016

X‐ray structure analysis of the synthesized arsanediylborate compounds (IV) (space group Pbcn, Z = 8) and (VI) (P21/c, Z=4) confirms the existence of a B=As double bond in both products.
ChemInform Abstract: Oxidatively Induced Reductive Elimination. A Novel Titanium Complex Resulting from C‐F Bond Activation.
Authors: BURK M. J. , STALEY D. L. , TUMAS W.
Published: May 2016

The titanacyclobutanes (I) react with tetrakis(trifluoromethyl)cyclopentadienone (II) in dichloromethane to produce the titanium complex (III).
ChemInform Abstract: Dichloromethane Addition to Rhodium‐β‐diketonate Complexes of Diphosphines and Pyridyl‐Substituted Diphosphines.
Authors: FENNIS P. J. , BUDZELAAR P. H. M. , FRIJNS J. H. G. , ORPEN A. G.
Published: May 2016

In the complexes (III) and (VII) only the P atoms coordinate to rhodium.
ChemInform Abstract: Palladium(II) Cyclic Carbene Complexes from 3‐Isocyanopropylacrylate. X‐Ray Structure of Cyclic cis‐(PdCl2(PPh3)(C‐N(H)‐(CH2)2‐N‐(CH2)3‐O‐C(O)‐CH=CH2)).
Authors: MICHELIN R. A. , MOZZON M. , ZECCA M. , CORAIN B. , PIAZZI O. , ZANOTTI G.
Published: May 2016

The title complex, prepared previously, crystallizes in P1 with Z=2.
ChemInform Abstract: Chemistry of α‐Aminonitriles. Part 3. Aziridine‐2‐carbonitrile, a Source of Racemic O3‐Phosphoserinenitrile and Glycolaldehyde Phosphate.
Authors: WAGNER E. , XIANG Y.‐B. , BAUMANN K. , GUECK J. + , ESCHENMOSER A.
Published: May 2016

Reaction of the aziridine (I) with TosOH (II) proceeds with > 90% regioselectivity to give the tosylserinenitrile (III).
ChemInform Abstract: Synthesis of All Four Stereoisomers of (E)‐Vitamin K1 (Phylloquinone); Analysis of Their Diastereoisomeric and Enantiomeric Purities and Determination of Their Biopotencies.
Authors: SCHMID R. , ANTOULAS S. , RUETTIMANN A. + , SCHMID M. , VECCHI M. , WEISER H.
Published: May 2016

For the first time all four stereoisomers (VIa), (VIb), (VIc) and (IX) of (E)‐vitamin K1 are synthesized in high chemical and stereoisomeric purity on two routes.
ChemInform Abstract: Ceramic Coatings on Ceramic Substrates by Liquid Metal Transfer.
Authors: SILVERMAN L. D. , ZDANIEWSKI W. A. , BRUNGARD N. L.
Published: May 2016

The liquid metal transfer technique is applied to form nitride and carbide coatings on ceramic substrates.
ChemInform Abstract: Structure of Nickel(II) Perbromate Hexahydrate at 296 K.
Authors: GALLUCCI J. C. , GERKIN R. E. , REPPART W. J.
Published: May 2016

The structure of Ni(BrO4)2·6 H2O at room temp. is found to be quite similar to that determined previously at 169 K. The water O atoms form a slightly distorted octahedron around Ni and Br is surrounded by four O atoms in virtually regular tetrahedral arrangement.
ChemInform Abstract: The Electrochromic Process at Nb2O5 Electrodes Prepared by Thermal Oxidation of Niobium.
Authors: GOMES M. A. B. , BULHOES L. O. S. , DE CASTRO S. C. , DAMIAO A. J.
Published: May 2016

Nb2O5 layers prepared by thermal oxidation of niobium in air at 580 °C are crystalline and exhibit good electrochromic response.
ChemInform Abstract: The Cathodic and Anodic Behavior of Iron in Acetate Buffer Solutions.
Authors: TAKAHASHI K. , MACDOUGALL B. , GRAHAM M. J.
Published: May 2016

The cathodic reduction characteristics of surface oxide films on iron in acetate or borate buffer solutions are strongly dependent on the nature, concentration and pH of the electrolyte.
ChemInform Abstract: Investigation of the Passivation and Breakdown of Passivity of Chromium by Cyclic Voltammetry and Ellipsometry.
Authors: GERRETSEN J. H. , DE WIT J. H. W.
Published: May 2016

At the potential corresponding to the maximum current, active dissolution and passivation of chromium occurs.
ChemInform Abstract: Singular Behavior of H3PW12O40 at High Temperature. Evidence for the Formation of an Anhydride Phase.
Authors: OULMEKKI A. , OLIVIER D. , HERVE G. , LEFEBVRE F.
Published: May 2016

The thermal degradation of H3PW12O40·xH2O (I), H6P2W21O71·yH2O (II), and H6P2W18O62·zH2O (III) is investigated.
ChemInform Abstract: Polymeric Xenon Materials: (‐Xe‐O‐TeF4‐O‐)n. Crystal Structure of HF·HO‐TeF4‐O‐Xe+AsF‐ 6.
Authors: TUROWSKY L. , SEPPELT K.
Published: May 2016

The title compound (V) crystallizes in space group P1 with Z=2.
ChemInform Abstract: Platinum Dichloride Complexes with (R,R)‐((Bicyclo(2.2.2)octane‐2,3‐diyl)bis(methylene))bis(diphenylphosphine)‐ or ‐bis(5H‐benzo(b)phosphinindole): New Catalyst Precursors for Enantioselective Hydroformylation.
Authors: CONSIGLIO G. , NEFKENS S. C. A.
Published: May 2016

The title complexes (Ia) and (Ib) are tested as catalyst precursors for the enantioselective hydroformylation of the aromatic olefins (II), (VI) and (VIII).
ChemInform Abstract: Et3B‐Induced Stereoselective Radical Addition of Ph3GeH to Carbon‐Carbon Multiple Bonds and Its Application to Isomerization of Olefins.
Authors: NOZAKI K. , ICHINOSE Y. , WAKAMATSU K. , OSHIMA K. , UTIMOTO K.
Published: May 2016

The isomeric ratios of the products depend on the reaction time, solvent and the ratio acetylene: Ph3GeH.
ChemInform Abstract: Diazotization of 1‐Aminocyclopropanecarboxylic Acid. Solution Chemistry of Oxaspiropentanone.
Authors: PIRRUNG M. C. , BROWN W. L.
Published: May 2016

The first evidence is reported for the existence of oxaspiropentanone (IV) in solution and its intermediacy in diazotization/substitution reactions of the acid (I) leading to products such as (V) or (VIII).
ChemInform Abstract: Lithium B Iso‐2‐ethylapopinocampheyl‐9‐borabicyclo(3.3.1)nonyl Hydride as an Improved Reagent for Asymmetric Reduction of Unhindered Aliphatic Ketones. Further Evidence for the Improved Enantioselectivity in Reductions by Reagents Containing Increased Steric Requirements at the 2‐Position of the Apopinene Structure.
Authors: RAMACHANDRAN P. V. , BROWN H. C. , SWAMINATHAN S.
Published: May 2016

The title chiral borohydride (Ic) (Eapine‐Hydride) is shown to be an improved reagent for the asym.
ChemInform Abstract: Preparation of (Z)‐3,4‐Didehydronorvaline, (E)‐ and (Z)‐3,4‐Didehydroornithine and (E)‐ and (Z)‐3,4‐Didehydro‐2,6‐diaminopimelic Acid.
Authors: HAVLICEK L. , HANUS J. , SEDMERA P. , NEMECEK J.
Published: May 2016

The synthesis of the title compounds (IV), (VII) and (X) starts from the readily available (Z)‐malonate (IIIa) which is then elaborated as shown in the scheme.
ChemInform Abstract: Isomerization of Heptacyclic Hydrocarbons to Triamantane.
Authors: KAFKA Z. , VODICKA L.
Published: May 2016

The title reaction is studied under various conditions using AlCl3 or AlBr3 as catalysts, different solvents and temperatures.
ChemInform Abstract: Synthesis and Liquid Crystalline Properties of the Compounds Consisting of a Schiff Base Type Mesogen and a Dyad Type Aromatic Ester Structure Interconnected Through the Central Hexamethylene Spacer.
Authors: JIN J.‐I. , KIM H.‐S. , SHIN J.‐W. , CHUNG B. Y. , JO B.‐W.
Published: May 2016

The title compounds (IIIa) prove to be enantiotropic and form smectic and nematic phases.
ChemInform Abstract: Synthesis and Structure of 1,11‐o‐Benzeno(2)orthocyclo(2)(4,5)tropolonophane.
Authors: FUKAZAWA Y. , OKAJIMA T. , USUI S.
Published: May 2016

The troponophane (I) is oxidized to form the endo‐peroxide (II) which is reduced with thiourea, producing the equilibrating regioisomers (III) and (IV).