bluuebunny/crossref_metadata_2025 huggingface dataset:
Can pharmacogenetics help patients under chronic treatment with coumarin anticoagulants?
Authors: López Isabel , Sangüesa Estela , Vancraenendonck Yves , Zuriaga Estefanía , Ribate María Pilar , García Cristina Belén
Published: October 2016

Vitamin K antagonists are highly effective antithrombotic drugs. However, appropriate dosing is difficult to establish owing to its narrow therapeutic window as well as widespread inter- and intra-individual variability in dosage. Compared with dosing solely based on clinical information, pharmacogenetics can help improve the therapy with coumarins by decreasing the time to reach a stable dose and reducing the risk of bleeding. Most of the studies about genotyping of patients using vitamin K antagonists have focused on predicting the stable dose. Two genes have been shown to have the most influence on dosing: VKORC1 and CYP2C9. Furthermore, genotyping of more genes, such as CYP4F2 and APOE, is also being included in some dosing algorithms. The role of genotype beyond the initial dose-titration phase is less clear. Thus, a proven genetically determined risk of unstable dose or bleeding could help with the selection of patients who require more frequent monitoring of dose. On the other hand, patients who have a genetically determined stable dose could self-monitor their international normalized ratio (INR), making the therapy less expensive and more convenient.
Interval arithmetic in calculations
Authors: Bairbekova Gaziza , Mazakov Talgat , Djomartova Sholpan , Nugmanova Salima
Published: October 2016

Interval arithmetic is the mathematical structure,
which for real intervals defines operations analogous
to ordinary arithmetic ones. This field of mathematics is
also called interval analysis or interval calculations. The
given math model is convenient for investigating various
applied objects: the quantities, the approximate values of
which are known; the quantities obtained during calculations,
the values of which are not exact because of rounding
errors; random quantities. As a whole, the idea of interval
calculations is the use of intervals as basic data objects.
In this paper, we considered the definition of interval
mathematics, investigated its properties, proved a theorem,
and showed the efficiency of the new interval arithmetic.
Besides, we briefly reviewed the works devoted to
interval analysis and observed basic tendencies of development
of integral analysis and interval calculations.
Influence of Transmitting Pointing Errors on High Speed WDM-AMI-Is-OWC Transmission System
Authors: Shatnawi Abdallah Ahmad , Bin Mohd Warip Mohd Nazri , Safar Anuar Mat
Published: October 2016

Inter-satellite communication is one of the revolutionary techniques that can be used to transmit the high speed date between satellites. However, space turbulences such as transmitting pointing errors play a significant role while designing inter-satellite communication systems. Those turbulences cause shutdown of inter-satellite link due to increase of attenuation during data transmission through link. The present work aims to develop an integrated data transmission system incorporating alternate mark inversion (AMI), wavelength division multiplexing (WDM), and polarization interleaving (PI) scheme for transmitting data 160 Gbps over inter-satellite link of 1,000 km under the influence of space turbulences. The performance of the integrated data transmission of 160 Gbps data up to 1,000 km will be evaluated under the influence of space turbulences by means of signal to noise ratio (SNR), total received power, bit error rate and eye diagram.
Crystal structure of 2-[(2-oxo-thiazolidine-3-carbonyl)sulfamoyl]-methy-benzoic acid methyl ester, C13H14N2O6S2
Authors: Chen Qing-Wu , Shen De-Long
Published: October 2016

C13H14N2O6S2, monoclinic, C2/c (no. 15), a = 28.1174(10)Å, b = 9.8677(4)Å, c = 11.2738(4)Å, β = 98.4457(11)°, V = 3094.0(2)Å3, Z = 8, Rgt(F) = 0.0382, wR
ref(F2
) = 0.1141, T = 296(2) K.
Investigation on hemolytic effect of poly(lactic co-glycolic) acid nanoparticles synthesized using continuous flow and batch processes
Authors: Libi Sumit , Calenic Bogdan , Astete Carlos E. , Kumar Challa , Sabliov Cristina M.
Published: October 2016

With the increasing interest in polymeric nanoparticles for biomedical applications, there is a need for continuous flow methodologies that allow for the precise control of nanoparticle synthesis. Poly(lactide-co-glycolic) acid (PLGA) nanoparticles with diameters of 220–250 nm were synthesized using a lab-on-a-chip, exploiting the precise flow control offered by a millifluidic platform. The association and the effect of PLGA nanoparticles on red blood cells (RBCs) were compared for fluorescent PLGA nanoparticles made by this novel continuous flow process using a millifluidic chip and smaller PLGA nanoparticles made by a batch method. Results indicated that all PLGA nanoparticles studied, independent of the synthesis method and size, adhered to the surface of RBCs but had no significant hemolytic effect at concentrations lower than 10 mg/ml.
Rational Grounds for Dialogue Between Archaeologists and Metal Detectorists in Spain
Authors: Rodríguez Temiño Ignacio
Published: October 2016

The sudden emergence of metal-detector users and subsequent swelling of their numbers rocked the
field of professional archaeology due to the impact that the use of metal detectors has on the conservation of
archaeological heritage. The situation has led to confrontation, polarisation and mistrust on both sides. These
problems are particularly severe in countries such as Spain, where the law does not allow the unauthorised
use of these devices. However, merely enforcing the law is not enough to resolve such conflicts, just as
encouraging ‘treasure hunting’ is no solution either. This paper uses sociological models to explain the lack
of communication and distance between the two groups with a view to finding principles that can be used
to establish rational grounds for communication. Here ‘rational grounds’ is understood to mean foundations
that will enable the convergence of the different interests whilst at the same time respecting the social function
of archaeological heritage. To this end, a model is suggested based on a new wave of scientific communication
aimed at including detectorists in archaeological research projects.
Private Metal Detecting and Archaeology in Norway
Authors: Gundersen Jostein , Rasmussen Josephine M. , Lie Ragnar Orten
Published: October 2016

Metal detecting has become a popular hobby in Norway. The use of metal detectors is legal, as long
as one has the landowner‘s permission, and complies with the Norwegian Cultural Heritage Act. As in other
countries, the relationship between private metal detecting and archaeology is complex. The perspectives
and experiences of archaeologists and heritage management representatives in regard to what challenges
and positive effects that arise from private metal detecting varies greatly. With this article we wish to address
various sides of the relationship openly.
LatMor: A Latin Finite-State Morphology
Encoding Vowel Quantity
Authors: Springmann Uwe , Schmid Helmut , Najock Dietmar
Published: October 2016

We present the first large-coverage finite-state open-source morphology for Latin (called LatMor)
which parses as well as generates vowel quantity information. LatMor is based on the Berlin Latin Lexicon
comprising about 70,000 lemmata of classical Latin compiled by the group of Dietmar Najock in theirwork on
concordances of Latin authors (see Rapsch and Najock, 1991) which was recently updated by us. Compared
to the well-known Morpheus system of Crane (1991, 1998), which is written in the C programming language,
based on 50,000 lemmata of Lewis and Short (1907), not well documented and therefore not easily extended,
our new morphology has a larger vocabulary, is about 60 to 1200 times faster and is built in the form of
finite-state transducers which can analyze as well as generate wordforms and represent the state-of-the-art
implementation method in computational morphology. The current coverage of LatMor is evaluated against
Morpheus and other existing systems (some of which are not openly accessible), and is shown to rank first
among all systems together with the Pisa LEMLAT morphology (not yet openly accessible). Recall has been
analyzed taking the Latin Dependency Treebank¹ as gold data and the remaining defect classes have been
identified. LatMor is available under an open source licence to allow its wide usage by all interested parties.
Decoloration and mineralization of aqueous solution of cationic (basic) dye Astrazon Black FDL by using gamma rays
Authors: Kantoğlu Ömer
Published: October 2016

Degree of decolorization due to the irradiation of aqueous solutions of commercial cationic (basic) Astrazon Black FDL textile dye was studied in this study. Factor effecting radiolysis of the dye such as dye concentration, absorbed dose, toxicity, COD, BOD5 and pH of solutions were studied at air, O2 saturated and H2O2 environments. Unirradiated Astrazon Black FDL was non-biodegradable, whereas it was biodegradable after irradiation. The biodegradability (BOD5/COD) increased at 2 kGy for Astrazon Black FDL in all solutions. The biorefractory organic compounds were converted into more easily biodegradable compounds having lower molecular weights. In optimum dose and pH determination experiments, 5 kGy pH 12 at air, 7 kGy pH 3 at O2 saturated, 9 kGy pH 3 at 2.6 mM H2O2 for Astrazon Black FDL were found as the optimum irradiation conditions. Toxicity level of unirradiated solutions was high, whereas toxicity level of irradiated solutions was lower.
Ins Blaue
Authors: Mettin Martin
Published: October 2016

Der Aufsatz widmet sich Derek Jarmans monochromem Film
Exact Solutions for a Coupled Korteweg–de Vries System
Authors: Zuo Da-Wei , Jia Hui-Xian
Published: October 2016

Korteweg–de Vries (KdV)-type equation can be used to characterise the dynamic behaviours of the shallow water waves and interfacial waves in the two-layer fluid with gradually varying depth. In this article, by virtue of the bilinear forms, rational solutions and three kind shapes (soliton-like, kink and bell, anti-bell, and bell shapes) for the Nth-order soliton-like solutions of a coupled KdV system are derived. Propagation and interaction of the solitons are analyzed: (1) Potential u shows three kind of shapes (soliton-like, kink, and anti-bell shapes); Potential v exhibits two type of shapes (soliton-like and bell shapes); (2) Interaction of the potentials u and v both display the fusion phenomena.
Environmental alterations in biofuel generating molecules in Zilla spinosa
Authors: Khattab Hemmat , El Marid Zeinab
Published: October 2016

Now days, production of fuels and petrochemicals from renewable lignocellulosic biomass is an indispensable issue to meet the growing energy demand. Meanwhile, the changes in the climate and soil topography influence the growth and development as well as canopy level of the lignocellulosic biomass. In this study, Zilla spinosa Turr (Zilla) plants with similar age and size were collected from three main sectors (upstream, midstream, and downstream) of Wadi Hagul during spring (April) and summer (July) seasons. Environmental stresses evoked reduction in the energy trapping pigments concomitant with increments in chlorophyll fluorescence in summer harvested plants particularly at downstream. Furthermore, the biofuels generating compounds including carbohydrate, lignin, and lipid making the plant biomasses are greatly affected by environmental conditions. Greater amount of lignin was estimated in summer harvested Z. spinosa shoots particularly at downstream. Moreover, the total oil content which is a promising source of biodiesel was considerably decreased during summer season particularly at downstream. The physical properties of the lipids major constituent fatty acid methyl esters determine the biofuel properties and contribute in the adaptation of plants against environmental stresses. Hence, the analysis of fatty acid profile showed significant modifications under combined drought and heat stress displayed in the summer season. The maximum increase in saturated fatty acid levels including tridecanoic acid (C13:0), pentadeanoic acid (C15:0), palmitic acid (C16:0), and stearic acid (C18:0) were estimated in spring harvested Z. spinosa aerial portions particularly at midstream. In spite of the reduction in the total oil content, a marked increase in the value of unsaturated to saturated fatty acids ratio and thereby the unsaturation index were achieved during the dry summer period. Henceforth, these seasonal and spatial variations in fatty acids profiles may contribute in the acclimatization of Z. spinosa plants to soil water scarcity associated with heat stress experienced during summer. In addition, the alterations in the fatty acid profiles may match biofuel requirements. In conclusion, the most adequate growing season (spring) will be decisive for achieving high lipid productivity associated with improved biofuel quality in terms of high saturated fatty acids percentage that improves its cetane number. However, the dry summer season enhanced the accumulation of greater amount of lignin that may enhance the biodiesel quantity.
DIAGNOSIS OF ENDOCRINE DISEASE: How reliable are free thyroid and total T3 hormone assays?
Authors: Welsh Kerry J , Soldin Steven J
Published: October 2016

Hypothyroidism is a very common disorder worldwide, for which the usual treatment is monotherapy with levothyroxine (L-T4). However, a number of patients treated with L-T4continue to report symptoms of hypothyroidism despite seemingly normal levels of thyroid-stimulating hormone (TSH), free-T3(FT3) and free-T4(FT4) measured by immunoassay. This review summarizes the limitations of the immunoassays commonly used to measure thyroid hormone levels and emphasizes the advantages of the role of liquid chromatography-tandem mass spectrometry (LC-MS/MS). Immunoassays for free thyroid hormone are affected by alterations in serum binding proteins that occur in many physiological and disease states. Multiple studies show falsely normal values for T3, FT3and FT4by immunoassay that are below the reference interval when measured by (ultrafiltration) LC-MS/MS, a reference method. We suggest evaluation of thyroid hormone levels by ultrafiltration LC-MS/MS for patients who continue to experience hypothyroid symptoms on LT-4. This may help identify the approximately 20% subset of patients who would benefit from addition of T3to their treatment regimen (combination therapy).
Incidence of Cushing’s syndrome in patients with significant hypercortisoluria
Authors: Hirsch Dania , Tsvetov Gloria , Manisterski Yossi , Aviran-Barak Nirit , Nadler Varda , Alboim Sandra , Kopel Vered
Published: October 2016

Objective

To investigate the incidence of Cushing’s syndrome (CS) in patients with significant hypercortisoluria and the performance of urinary free cortisol (UFC) screening.

Design

Retrospective file review.

Methods

The computerized database of a publicly funded health maintenance organization (HMO) in Israel was searched for all patients who underwent 24-h UFC testing in 2005–2014 with a result of more than twice the upper limit of normal (ULN). The patients’ medical files were reviewed for a subsequent diagnosis of CS by an expert endocrinologist. Findings were evaluated for patterns in CS diagnosis and UFC testing over time.

Results

Of 41 183 individuals tested, 510 (1.2%) had UFC >2× ULN (214 >3× ULN). Eighty-five (16.7%) individuals were diagnosed with CS (63 female and mean age 47.2 ± 15.1 years), mainly Cushing’s disease (55.3%) or adrenal Cushing’s syndrome (37.6%). The number of UFC tests increased steadily, from 1804 in 2005 to 6464 in 2014; yet, the resultant detection rate of CS remained generally stable. The calculated incidence of CS in the general HMO-insured population based only on the patients identified in the present cohort was 4.5 new cases/million/year (median 4.9/million/year, range 1.7–5.9/million/year), which was also relatively stable. The most common reason for referral for UFC screening was obesity. Of the 148 patients before bariatric surgery with UFC >2× ULN, 2 were diagnosed with CS.

Conclusions

The incidence of CS is higher than previously suggested. The consistently increasing number of UFC tests being performed has not been accompanied by a similar increase in CS detection rate. The expected yield of routine UFC testing before bariatric surgery is low.
Can Learning Explain Boom-Bust Cycles In Asset Prices? An Application to the US Housing Boom
Authors: Caines Colin
Published: October 2016

Explaining asset price booms poses a difficult question for researchers in macroeconomics: how can large and persistent price growth be explained in the absence large and persistent variation in fundamentals? This paper argues that boom-bust behavior in asset prices can be explained by a model in which boundedly rational agents learn the process for prices. The key feature of the model is that learning operates in both the demand for assets and the supply of credit. Interactions between agents on either side of the market create complementarities in their respective beliefs, providing an additional source of propagation. In contrast, the paper shows why learning involving only one side on the market, which has been the focus of most of the literature, cannot plausibly explain persistent and large price booms. Quantitatively, the model explains recent experiences in US housing markets. A single unanticipated mortgage rate drop generates 20 quarters of price growth whilst capturing the full appreciation in US house prices in the early 2000s. The model is able to generate endogenous liberalizations in household lending conditions during price booms, consistent with US data, and replicates key volatilities of housing market variables at business cycle frequencies.
Collaborated understandings of context-specific psychosocial challenges facing South African school learners: a participatory approach
Authors: Setlhare Rubina , Wood Lesley , Meyer Lukas
Published: October 2016

South African teachers are not sufficiently equipped to address psychosocial challenges that they encounter in under-resourced contexts among learners at school, and which impact negatively on learning and teaching. In this article, we report on the first cycle of a community-based participatory action research project undertaken with teacher participants to facilitate a collaborative understanding of the contextual psychosocial challenges that learners face. The aim of the study was to equip teachers with sustainable capacity to conduct a participatory action learning and action research (PALAR) enquiry that would enhance their ability to identify and address contextual psychosocial challenges to promote wellness. Following a PALAR design, we collaborated with 10 volunteer teachers for the generation of qualitative data through relationship building activities, individual interviews, the creation of visual artefacts, and informal group discussions. Data were analysed thematically in collaboration with the community of participants. Findings suggest that the process assisted the teachers to gain a deeper understanding of learners' psychosocial challenges, encouraged a sense of group identity among coresearchers, and fostered their agency to begin to address the identified challenges and to network with community stakeholders to promote wellness among themselves and among learners.
Science and Poetry as Allies in School Learning
Authors: Donald Claire , Barker Miles
Published: October 2016

In this paper, we propose that when learners in school classrooms write up a scientific observation, firstly as a science report and then as a poem, the way they express insights appropriate to each format can advance learners' observation skills and developing insight of the natural world. This could lead to productive learning alliances across traditional discipline boundaries and, by surfacing the cultural dimension of science within a sociocultural frame, promote social change. Tracing the domains of science and poetry over the last two centuries, we discern three areas of synergy: culture, creativity, and the curriculum. An integrative classroom exercise was devised to support these synergies explicitly with the intention of inspiring learners to write (say) what they really mean (see). We describe the encouraging results of a preliminary trial of this writing exercise with one small class of South African high school students, and outline possible future directions for research prompted by this work.
"Hear our voices": a collective arts-based self-study of early-career academics on our learning and growth in a research-intensive university
Authors: Masinga L. , Myende P. , Marais A. , Singh-Pillay A. , Kortjass M. , Chirikure T. , Mweli P.
Published: October 2016

Early-career academics (ECAs) experience challenges with their integration into higher education institutions due to what is considered inadequate (or lack of) provision for effective professional development. In this article, we present our journey through a collective arts-based self-study project as ECAs guided by three seasoned academics: Kathleen Pithouse-Morgan, Daisy Pillay, and Inbanathan Naicker. We share our personal experiences and challenges faced as ECAs at the University of KwaZulu-Natal; to achieve this, we used a social constructivist lens to collectively engage in conversations as we constructed new understandings of ourselves and experiences as ECAs. We show how, through the research, we learned to form and position our learning and growth within the changing university setting. We adopted a collective arts-based, self-study approach to explore our experiences and what we felt needed to happen to provide meaningful development for the newly appointed as we journey through the unclear grounds of university life. We make visible how we as ECAs feel overwhelmed when entering higher education institutions because of the need to balance research, teaching, and other demands of academic life. We find a strong need for collaborative engagement between ECAs and experienced academics. In addition, establishment of a healthy working environment and policy specific to addressing the needs of ECAs would assist in providing clear support as ECAs transition into experienced academics. Finally, we demonstrate how we took our findings forward, and describe both the resistance and support we experienced.
Experimental investigation of local scour around circular bridge piers under steady state flow conditions
Authors: Aksoy A , Eski O
Published: October 2016

Local scour around bridge piers is one of the main causes of bridge failures. In this study, scour depths and scour hole geometries around circular bridge piers were investigated under clear water scour conditions for various flow rates. The experiments were carried out in a rectangular flume 80 cm wide, 18.6 m long and 75 cm high by using uniform sediment with a median diameter of 1.63 mm and geometric standard deviation of 1.3. The flow rates and approach flow depths were measured with an electromagnetic flow meter and ultrasonic level sensors, respectively. A new empirical equation for the determination of scour depth is proposed based on the experimental findings of the present study and on experimental data available in the literature. The experimental results were also compared with those calculated using several empirical equations developed by previous studies. The proposed new equation to predict scour depth around a circular bridge pier was evaluated in terms of determination coefficient (R2) and scatter index (SI). The Fisher (f)test was also applied to test the statistical significance of the proposed equation.
Novos Brinquedos Para Crianças Mortas
Authors: Amaral Thiago De Barros Espíndola
Published: October 2016

Este trabalho descreve o resultado de uma pesquisa de campo e de observação etnográfica, realizada no Cemitério Parque, na cidade de Limeira, SP no dia dois de novembro de 2015. O pesquisador durante in loco observou os diversos eventos da religiosidade produzida e a relação dos parentes com seus mortos e a função da religião neste dia. especificamente, durante esta observação identificou-se uma prática ritual, até onde se sabe inédita em que brinquedos eram depositados nos túmulos de pessoas mortas na infância sob um ritual religioso descrito neste artigo.
Quimeras em Diálogo
Authors: Nobre Emerson
Published: October 2016

SEVERI, Carlo; LAGROU, Els (Orgs.) Quimeras em diálogo. Grafismo e figuração na arte indígena. Rio de Janeiro: 7 Letras, 2013, 334 p.
Animal para toda Obra: fauna ritual em sambaquis
Authors: Klokler Daniela
Published: October 2016

Resumo: pesquisas sobre as práticas rituais dos povos sambaquieiros demonstraram avanços nos últimos 15 anos, desenvolvimento também sentido em estudos sobre concheiros em outros países. Mudanças nas perspectivas teóricas impactaram sobremaneira o entendimento das relações entre comunidades pescadoras-coletoras e o mundo animal. Atualmente não é mais possível considerar os depósitos faunísticos em sambaquis como resultantes de acumulações aleatórias de refugo, mas sim como correspondentes a deposições episódicas coordenadas e concomitantes a atividades rituais funerárias. Resultados sugerem papel importante de animais aquáticos nos rituais em festins funerários. Análises zooarqueológicas foram essenciais para gerar subsídios para estudos sobre comportamento ritual. Palavras-chave: Sambaquis. Zooarqueologia Social. Ritual.
Conversion of gas turbine engine oil system
Authors: Boev A. A. , Grishanov O. A.
Published: October 2016

The paper emphasizes the increasingly important role of gas turbines on the power generation and gas pumping market. One of the variants of manufacturing such power plants consists in the conversion of aircraft engines into industrial gas turbine drives. The authors review the advantages of this type of production. The paper describes the operating conditions of such gas turbines and major challenges encountered in designing oil systems for aeroderivatives of this type. Conservatism of aircraft engine developers does not make it possible to realize the changes in requirements to industrial power plants to the full extent, which results in imperfection of the oil system structure as it is re-designed for ground application. The paper presents the main trends in industrial gas turbine oil system development. Three levels of oil system conversion are defined: maximum (maximum possible application of the existing hardware, in which case achieving high gas turbine service life is impossible), medium (aircraft engine oil system components that do not significantly affect the engine life are partially preserved, while other components are re-designed for ground application), minimum (complete replacement of the oil system elements aimed at achieving the highest performance characteristics).
Biochemical and molecular evidences for the antitumor potential of Ginkgo biloba leaves extract in rodents.
Authors: Ahmed Hanaa H , Shousha Wafaa Gh , El-Mezayen Hatem A , El-Toumy Sayed A , Sayed Alaa H , Ramadan Aesha R
Published: October 2016

Hepatocellular carcinoma (HCC) is one of the deadliest primary cancers, with a 5-year survival rate of 10% or less. This study was undertaken to elucidate the underlying biochemical and molecular mechanisms in favor of N-nitrosodiethylamine-induced hepatocellular carcinoma. Furthermore, the aim of this work was extended to explore the efficacy of Ginkgo biloba leaves extract in deterioration of HCC in rats. In the current study, HCC group experienced significant downregulation of ING-3 gene expression and upregulation of Foxp-1 gene expression in liver. Treatment of HCC groups with Ginkgo biloba leaves extract resulted in upregulation of ING-3 and downregulation of Foxp-1 gene expression in liver. In addition, there was significant increase in serum alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA) and glypican-3 (GPC-3) levels in HCC group versus the negative control group. In contrast, the groups with HCC subjected to either high or low dose of Ginkgo biloba leaves extract elicited significant reduction (P
Plenitud de Amado Nervo: ¿prosa aforística o poemas en prosa?
Authors: Vigne Pacheco Ana
Published: October 2016

La autora hace un estudio de la brevedad estilística del libro Plenitud (1917) como un proceso de depuración prosística y espiritual de Amado Nervo, autor que cultivó la forma breve no sólo para congraciarse con el lector agobiado por el ritmo trepidante de la vida en el siglo XX, sino que buscó que los textos breves le sirvieran como guías de perfeccionamiento espiritual. Además, es posible que los símbolos de estos pequeños textos tuvieran una inspiración no sólo mística sino esotérica.
Jaime Sabines y la Biblia
Authors: Plascencia Saavedra Mónica
Published: October 2016

La autora hace un repaso del gran código bíblico en la poesía de Jaime Sabines. Se comparan los símbolos del Antiguo Testamento con los símbolos poéticos de los poemas de Sabines. La autora demuestra que uno de los pasajes bíblicos más importantes a que alude el poeta es el libro de Job, y es que Job como Sabines se rebela contra la teología tradicional, contra la palabrería y contra las mentiras y las injusticias que Dios parece tolerar.
Alfonso Reyes en Libra y Sur
Authors: Corral Rose
Published: October 2016

En México con los Contemporáneos, en Argentina con los integrantes de las revistas Proa y Martín Fierro, y aún antes, en España, siendo él mismo todavía joven. Alfonso Reyes siempre buscó la cercanía de las jóvenes generaciones de escritores. En Sur el papel de Reyes en los primeros años de la revista parece haber sido principalmente de contención o moderación, en particular frente a los excesos del americanismo, en la revista Libra se da un primer ensayo, extremas de la vanguardia martinfierrista, un intento por ampliar los horizontes de los jóvenes que les permitiera dialogar con otras tradiciones.
Lola Casanova: La Malinche invertida en la cultura nacional mexicana
Authors: McKee Irwin Robert
Published: October 2016

La leyenda de Dolores Casanova y coyote Iguana es una historia fronteriza que reta los límites del imaginario nacional en México. Lola ha sido figura inquietante para los mexicanos que conocen su leyenda desde que entró en el discuros público en 1850. Este trabajo esboza la trayectoria de la leyenda de Lola Casanova y medita sonre su incómoda identidad racial dentro de la ortodoxia nacionalista mexicana.
Rasgos autobiográficos en Rito de iniciación de Rosario Castellanos
Authors: Bustamante Bermúdez Gerardo
Published: October 2016

En este trabajo, el autor demuestra que en la novela Rito de iniciación, Rosario Castellanos estaba hablando de sí misma y, además, que las problemáticas de su personaje fueron en gran medida las de ella misma y las de otras mujeres intelectuales de su generación que tuvieron que luchar en un ambiente literario predominantemente masculino. Al igual que su protagonista, la autora ejerció el oficio literario para comprender su entorno y comprenderse como ser humano. Las correspondencias nos hablan de la necesidad de Castellanos de dejar el testimonio de sus años de formación.
De la autobiografía y la sicalipsis en Novo y Nandino
Authors: Lara Anguiano Gerardo
Published: October 2016

Con pretensiones modestas, este análisis comparativo de las autobiografías de Salvador Novo y Elías Nandino parte de la reflexión sobre el concepto de la literatura como expresión privilegiada d elo humano, reconocemos los alcances de la autobiogarfía literaria y distinguimos algunas similitudes y diferencias entre estas historias de vidas sicalípticas. La autobiografía auxilia en el afán de articular mundo, texto y yo.
Acercamiento literario y biográfico a Pedro Ángel de Gorostiza y Cepeda: documentos y pistas sueltas
Authors: Saura Alfonso
Published: October 2016

Trabajo de archivo en el que el autor documenta la vida del dramaturgo Pedro Ángel de Gorostiza, hermano de Manuel Eduardo de Gorostiza, escritor que eligió la nacionalidad mexicana, a diferencia de Pedro Ángel. Además de esclarecer la vida del dramaturgo español, nos ilustra la vida teatral española de principios de siglo XIX, en donde la sensibilidad romántica iba cambiando al realismo y al costumbrismo.
De bandidos a trabajadores: el proyecto económico liberal en El Zarco de Ignacio Manuel Altamirano
Authors: Herr Robert
Published: October 2016

Lectura de la novela de Altamirano a la luz de los proyectos sociales del pensamiento liberal. Herr examina el modelo de consolidación nacional basado en una política económica liberal y toma en cuenta estudios historiográficos sobre el campo morelense y el bandolerismo social durante el siglo diecinueve. Este ensayo complementa la crítica literaria en torno a El Zarco, novela romántica que incluye sutilmente propuestas de unión racial y política de la nación. El autor analiza, además, los arquetipos masculinos de los protagonistas desarrollados, como alegorías de las ideologías conservadora y liberal.
Un encuentro peregrino entre Jorge Aguilar Mora y Gabriel García Márquez, con una nota sobre Suetonio
Authors: Vanden Berghe Kristine
Published: October 2016

En este artículo se analizan las coincidencias más llamativas de Una muerte sencilla, justa, eterna. Cultura y guerra durante la revolución mexicana de Aguilar Mora; y Los Doce cuentos peregrinos de García Márquez. Los dos textos tienen un narrador que habla en primera persona del singular, que se parece al autor e incluyen una cantidad sorprendente de coincidencias.
Soledad y comunión, ejes del pensamiento poético en La hija de Rappaccini de Octavio Paz
Authors: González Pelayo Irma
Published: October 2016

El autor define a La hija de Rappaccini como un drama alegórico-simbólico-poético que cronológicamente nos remite al periodo surrealista de Octavio Paz. Al  Analizar el tratamiento de dos ejes de su pensamiento poético: la soledad y la comunión, considera alternativamente los puntos de contacto con el método poético del autor y algunos de sus intertextos; además, resalta la unidad y recurrencia de su temática y contrasta las técnicas utilizadas, tomando en cuenta que los poemas y ensayos se iluminan entre sí y permiten ver la congruencia de poesía y poética.
Emmanuel Carballo, David Huerta, Alfredo Pavón, et al. Paquete: Cuento (La ficción en México), 1990.
Authors: Albarrán Claudia
Published: October 2016

Bajo el título Paquete: Cuento (La ficción en México) se reúnen doce ponencias de los escritores que participaron en el Encuentro de Investigadores del Cuento Mexicano convocado por la Universidad Autónoma de Tlaxcala en 1989. Es una publicación que aspira a definir los múltiples caminos -genéricos, históricos, críticos- que han recorrido nuestro relatos desde el siglo XIX hasta nuestros días.
Cristóbal Nonato, novela irreverente del descubrimiento
Authors: Poot Herrera Sara
Published: October 2016

La obra narrativa de Carlos Fuentes, denominada por él mismo La edad del tiempo, sufre un cambio de piel y celebra un festín del lenguaje, Cristóbal Nonato. Las formas cosmológicas que dominan y predominan en la zona sagrada y consagrada de este escritor se instauran en esta novela que alude y se adelanta al quinto centenario del descubrimiento de América; se inscribe así en la celebración polémica de este suceso, al que conmemora con una particularidad muy especial: su irreverencia.
Historia de la lectura en México. México: Seminario de la Historia de la educación en México/Ediciones del Ermitaño/El Colegio de México. 1988.
Authors: Flores Enrique
Published: October 2016

La Historia de la lectura en México, su valor radica en documentar, más que una historia de la lectura, la historia de su enseñanza y -en un ámbito más restringido aún- la de las políticas oficiales que la promueven, la ordenan y delimitan. El libro presenta algo más: historias vivas de lectores; técnicas modernas y hábitos tradicionales; materiales olvidados de lectura en un enfoque global.
Revisión de Mariano Azuela
Authors: Martínez José Luis
Published: October 2016

Con una obra clásica de nuestra literatura moderna, Los de abajo (1916), Mariano Azuela (1873-1952) inicia la novela de la Revolución. Ésta y sus otras novelas de tema revolucionario forman parte de una extensa obra novelesca, importante y poco estudiada en conjunto.
El luto humano y la narrativa mexicana que lo precede
Authors: Negrín Edith
Published: October 2016

El luto humano (1941), la segunda novela de José Revueltas, tematiza la historia de México en el siglo XX, a través de un hilo anecdótico muy sencillo: un grupo de campesinos sale de su pueblo en busca de nuevas tierras, tras el fracaso de un sistema de riego. El nivel referencial, temático, que considera la historia como texto, es sólo un aspecto del proceso intertextual. Mediante la intertextualidad, el texto entra en la historia en un amplio sentido, y la historia, en el texto.
Manuel Maples Arce, pre-estridentista: Rag. Tintas de abanico, 1920
Authors: Meyer-Minnemann Klaus
Published: October 2016

El primer libro de Maples Arce aparece, a todas luces costeado por el autor, en 1920, en una librería editora veracruzana, bajo el título de Rag. Tintas de abanico. El librito, reproducido en estas páginas de Literatura mexicana, es hoy prácticamente inasequible. Ninguna de las grandes bibliotecas de México lo registra.
"Paréntesis" (1882), cuento parisiense de Manuel Gutiérrez Nájera
Authors: Clark de Lara Belem
Published: October 2016

Por donde se sube al cielo incluye en su versión original, el relato "Paréntesis". Este cuento no participa de la secuencia en las acciones ni responde a las necesidades estructurales o de tensión emocional de la narración, sino que, por el contrario, rompe totalmente con su temática, y tenemos que considerarlo como un texto independiente.
Aralia López González. La espiral parece un círculo. La narrativa de Rosario Castellanos. Análisis de "Oficio de tinieblas" y "Álbum de familia". México: Universidad Autónoma metropolitana, 1991.
Authors: Jiménez de Báez Yvette
Published: October 2016

El estilo de Aralia López en este libro es rico en matices y referencias. Se trata de un discurso crítico marcadamente socio histórico, pero enraizado en la concreción literaria textual.El libro consta de una Introducción y cuatro capítulos.
Los enredos de una pieza. El contexto histórico-teatral de El encanto es la hermosura o La segunda Celestina de Salazar y Torres, Vera Tassis y sor Juana
Authors: Austin O´Connor Thomas
Published: October 2016

En 1990 Guillermo Schmidhunber publicó en México una edición de La segunda Celestina en la cual adjudicó a sor Juana la conclusión de una comedia inconclusa del poeta y dramaturgo mexicano hispanoamericano, Agustín de Salazar y Torres (1642-1675). Hasta fecha reciente éste final fue considerado anónimo por los bibliógrafos. Otra versión más conocida, intitulada El encanto es la hermosura y el hechizo sin hechizo, contiene una conclusión escrita por don Juan de Vera Tassis y Villarroel, editor de las obras completas de Salazar.
Rebelión histórica y metafísica en Los de abajo de Mariano Azuela
Authors: St. Ours Kathryn
Published: October 2016

De acuerdo con Bajtín (1978), cualquier novela constituye en su conjunto un fenómeno lingüístico ideológicamente saturado que, en su forma más lograda, se constituye un foro dialógico de una infinidad de voces conscientes e inconscientes, pasadas y presentes, intencionadas pero jamás monolíticas. Los de abajo se ofrece, a través  de su subtítulo "Cuadros y escenas de la revolución mexicana", como un buceo dentro de ese mundo perturbado poblado de múltiples protagonistas.
Cartas de amor de un panadero novohispano
Authors: Company Company Concepción
Published: October 2016

El material que aquí presenta la autora, son siete cartas inéditas de tema amoroso escritas en la ciudad de México hacia 1687 por Agustín Cortés, vecino y natural de esta ciudad, de oficio panadero, quien en el momento de escribirlas debía tener unos cuarenta y cinco años aproximadamente.Las cartas están escritas en papel manila de diferentes tamaños. Son interesantes desde el punto de vista lingüístico y social, tanto porque reflejan muy de cerca la lengua hablada en la Colonia por mexicanos no instruidos, como porque nos ponen en contacto con ciertas facetas de la vida cotidiana en la Nueva España.
Peter Beardsell. A Theatre for Cannibals. Rodolfo Usigli and the Mexican Stage. London: Associated University Presses, 1992.
Authors: Rivera Octavio
Published: October 2016

A Theatre for Cannibals llama Beardsell a su trabajo sobre la dramaturgia usigliana, utilizando una frase del propio Usigli.El autor del libro trabaja con la obra de Usigli y la distribuye en cuatro grupos principales: obras políticas, sociales, psicológicas e históricas, de acuerdo con las semejanzas temáticas y el desarrollo de un mismo orden de ideas.
Aportación bibliográfica. Efraín Huerta (1914-1982). II
Authors: Ocampo Alfaro Aurora Maura , Navarrete Maya Laura
Published: October 2016

La bibliografía de y sobre el poeta y periodista Efraín Huerta que ofrecemos en este volumen es una contribución en homenaje a su memoria, al cumplirse diez años de su partida. La bibliografía consta de cuatro partes: a) Libros; b) Hemerografía; c) Homenajes; d) Referencias.
Understanding the genetic bases of adaptation to soil water deficit in trees through the examination of water use efficiency and cavitation resistance: maritime pine as a case study
Authors: Plomion Christophe , Bartholomé Jérome , Bouffier Laurent , Brendel Oliver , Cochard Hervé , De Miguel Marina , Delzon Sylvain , Gion Jean-Marc , Gonzalez-Martinez Santiago C , Guehl Jean-Marc , Lagraulet Hélène , Le Provost Grégoire , Marguerit Elisa , Porté Annabel
Published: October 2016

This article provides a comprehensive view on the existing knowledge related to adaptation to soil water deficit in maritime pine, a conifer species widely planted in the southwestern Europe. It synthesizes discoveries made in ecophysiology, quantitative and population genetics as well as in genomics, combining several layers of information at the genotypic, phenotypic and environmental levels. Particular focus is given to two major traits: water-use efficiency (WUE) and cavitation resistance (CR). The former is related the maintenance of productivity during periods of lower soil water availability, whereas the latter is tightly linked to survival during severe drought. The development of high throughput phenotypic technologies have made it possible to estimate genetic and environmental variance components of these key traits, providing clues about their suitability for breeding and the evolutionary forces that have shaped their variability. Both CR and WUE were screened in different ecotypes as well as in the Aquitaine breeding population, the main genetic resource of the most advanced maritime pine breeding program in Europe.While the unexpectedly low level of variation of CR within and between natural populations will most likely hamper its use in breeding application, for WUE the medium heritability, absence of unfavorable phenotypic and genetic correlations with diameter growth, as well as the high inter-site correlation and weak genotype-by-environment interaction indicates that artificial selection could be applied for this trait without unfavorable consequences for radial growth, at least within the Aquitaine provenance. On the other hand, recent advances in sequencing and genotyping technologies have contributed to reveal the genetic architecture (i.e. number, location and effect of quantitative trait loci) of these two traits. In combination with ultra-dense genetic linkage map and functional genomics approaches, these findings will contribute to identify positional and expressional candidate genes that should be validated by association genetics and eventually introduced in genomic prediction models to make such knowledge useful to improve tree breeding.This review also opens up new research avenues and raises key questions on how to promote adaptation to the challenge of soil water deficit through genetic approaches in this species. If the results obtained so far in maritime pine can only applied to the tested genetic material, we however believe that the overall strategy presented here can be considered and cited as an example of integrative research to better understand the genetic bases of adaptation to soil water deficit in any forest tree species.
Study of different biogenic amines in wines from two protected designations of origin (PDOs) in Murcia (Spain) multivariate classification
Authors: Villalba-Rodríguez Alicia , Fernández-Fernández José Ignacio , Martínez-Cutillas Adrián , Gil-Muñoz Rocío
Published: October 2016

Aims: Biogenic amines were determined in 109 wines from two wineproducing areas (Jumilla and Bullas PDOs) situated in the Murcia region (SE Spain).

Methods and Results: Biogenic amines (histamine, ethylamine, tyramine, phenylethylamine, putrescine, tryptamine and cadaverine) were analysed by RP-HPLC with o-phthaldialdehyde precolumn derivatization and fluorescence detection. Histamine and putrescine were the most prevalent amines in Jumilla wines (49 and 48%, respectively), whereas tryptamine and putrescine were the most prevalent ones in Bullas wines (19 and 38%, respectively). Multivariate analyses were used to attempt a preliminary classification of wines according to production area.

Conclusion: In general, wines from Jumilla PDO had a higher biogenic amine content than wines from Bullas PDO; however, all of them were safe from the health point of view.

Significance and impact of the study: This study demonstrates that the Jumilla and Bullas wines studied are safe to drink and that geographical classification based on biogenic amine profiles is not possible with the analysed samples.
Leaf thickness and structure of Vitis vinifera L. cv. Albariño clones and its possible relation with susceptibility to downy mildew (Plasmopara viticola) infection
Authors: Alonso-Villaverde Virginia , Boso Susana , Santiago José-Luis , Gago Pilar , Rodríguez-García María Isabel , Martínez María-Carmen
Published: October 2016

Aims: The grapevine (Vitis vinifera L.) cultivar Albariño is currently the most economically important in Galicia (northwestern Spain). Earlier works assessing the natural susceptibility to downy mildew leaf infection (both in the laboratory and in the field), carried out in the collection of Albariño clones at the Misión Biológica de Galicia (CSIC), showed great differences among the clones (Boso et al., 2004b, 2005b, 2006; Boso and Kassemeyer, 2008). The aim of the present work is to highlight the histological differences in leaves, in particular thickness and structure, among the 11 different Albariño clones and to find out their possible relation with their natural susceptibility to Plasmopara viticola.

Methods and Results: Transverse sections of adult leaves where prepared and observed under light microscope. The area corresponding to the different leaf layers was measured. The results showed significant differences between the clones regarding the thickness of the spongy mesophyll. The clones CSIC-4 and CSIC-1 had the thickest spongy mesophyll (average mean = 14316.8 μm2) whereas CSIC-3 showed the thinnest one (11548.1 μm2).

Conclusion: The CSIC-3 clone, one of the least susceptible clones to P. viticola in previous studies, showed the thinnest and most compact spongy mesophyll. On the contrary, the CSIC-1 clone had the thickest spongy mesophyll and was also one of the most susceptible to this pathogen. Therefore, it could be possible to relate their histological leaf characteristics with their different levels of natural susceptibility to P. viticola.

Significance and impact of the study: This work contributes to the understanding of the link between histological characteristics of leaf layers and mesophyll cells and the different natural susceptibility of grapevines to downy mildew. This may become in the future a valid tool to be used during clonal selections in grapevine breeding programs.