bluuebunny/crossref_metadata_2025 huggingface dataset:
BİR TEPKİ ÜRETİMİ VE POLİTİK AKSİYON ARACI OLARAK KARİKATÜRLER: HAMAS ÖLÇEKLİ SOSYAL AĞLAR ÜZERİNDEKİ KARİKATÜRLERİN İNCELENMESİ
Authors: GÖRGÜLÜ Yusuf
Published: January 2022

Bu çalışmanın amacı, İsrail- Filistin çıkmazında önemli bir konumda bulunan Hamas’ın sosyal ağ üzerinden inşa ettiği propaganda içeriklerinin tespiti ve bu ağlar üzerinde (FEM ve El- Fatih) İsrail- Filistin sorununa yönelik sunulan karikatürlerin göstergebilimsel açıdan incelenmesidir. Çalışmada Hamas’ın politik aksiyonları ile İsrail’e ilişkin politik tutumlarının karikatürlerde ne ölçüde gerçekleştirildiği ve İsrail’e ilişkin politik aksiyonlarla karikatürlerde sunulan ideolojik örüntüsel alanın paralellik gösterip göstermediği, İsrail’e ilişkin siyasilerin nasıl temsil edildikleri ve bunların hangi çerçeveler ile sunuldukları tespit edilmeye çalışılmıştır. Araştırma yapılan zaman dilimi İsrail- Hamas- İran ve Lübnan Hizbullah’ının yoğun politik söylem ve politik aksiyonlarını şekillendirdiği bir dönemi kapsamaktadır. Bu dönemde politik aksiyonların sunumunda çeşitli kitle iletişim araçları ile çok yönlü bir propaganda edinimi gerçekleştirilmiştir. Çalışmada ele alınan karikatürler Barthes’in yan anlam- düz anlam metaforu ile çözümlenmiştir.Araştırma sonucuna göre, Hamas ölçekli sosyal ağ platformlarında yer alan karikatürler, Hamas’ın politik aksiyonlarına paralel ölçekte sunulmuştur. Bu karikatürlerin sunumunda sert anlam tonlamaları göze çarpmıştır. Ele alınan karikatürlerde propaganda edinimi çok yönlüdür. Bir yanda Filistin ve Kudüs’ün bağımsızlığı için mücadele içerisinde yer alan halk kitleleri ve onların bu mücadelede şehit verdikleri, diğer tarafta ise düşmanların masum insanlara karşı işledikleri suçların gösterilmesi şeklindedir. Çalışmada Hamas’ın “direniş fikri” yönelimli karikatürlerin resmedildiği gözlenmiştir. İncelenen karikatürlerin ideolojik ve politik yönelimli oldukları ve genel gündemi yakalamaya yönelik bir stratejik hedef doğrultusunda resmedildikleri sonucuna ulaşılmıştır.
İSLAM’IN SİYASİ MODELİNİN ÖZGÜNLÜĞÜNE VE MÜSLÜMAN TOPLUMLARIN HAREKET TARZINA İLİŞKİN BİR DEĞERLENDİRME
Authors: ÖZDEMİR Gürbüz
Published: January 2022

Çatışmacı bir paradigmaya dayanan Batı düşüncesi, komünizmin çöküşüyle birlikte yerine yeni bir “öteki” olarak İslam’ı yeniden keşfetmiş ve İslam’ın demokrasiyle uyumu tartışmasını başlatmıştır. Ancak tartışma, birçok yönüyle akademik olmayan bir düzlemde yürütülmüştür. Bu çalışmada; İslam’ı, demokrasiyi merkeze alarak demokrasiyle tek taraflı olarak kıyaslamanın objektif bir yöntem olmadığı ifade edildi. Eğer konu, hiçbir rezerv konulmadan objektif bir şekilde ele alındığı taktirde, İslam’ın demokrasiyle tek taraflı şekilde kıyaslanmayacak bir özgün modele sahip olduğunun anlaşılacağı vurgulandı. Bu bağlamda öncelikle İslam’ı demokrasiyle, demokrasi merkezli tek taraflı kıyaslamanın yanlışlığı ortaya konuldu. İkinci olarak İslam’ın temel kaynaklarından hareketle İslam’ın siyasete bakışı ve sahip olduğu özgün modelin ilke ve temel esasları ile bu modelin, demokrasiye benzeyen yönleri olduğu gibi farklılıklarının da bulunduğu ele alındı. Sonrasında ise farklı sebeplerden dolayı, bu özgün modelin günümüzde uygulanma imkânı bulunamadığı ve Müslüman toplumların ikilem içerisinde kaldığı belirtildi. Kalınan ikilem ise Müslüman toplumların baskıcı rejimlerin tasallutu altında kalmasına yol açtığı ifade edildi. Bütün bunların sonucu olarak, Müslüman toplumların demokrasiyi, mevcut şartlarda bu baskıcı ve sıkıntılı durumdan kurtulup daha özgür bir ortamda yaşayabilmeleri için despotik modellere nazaran tercih edilebilir bir alternatif olarak görmeleri gerektiği ortaya konuldu.
LİSANS ÖĞRENCİLERİNİN MUHASEBE DERSİNE BAKIŞI: GİRESUN ÜNİVERSİTESİ ULUSLARARASI TİCARET VE FİNANSMAN ÖĞRENCİLERİ ÜZERİNE BİR ARAŞTIRMA
Authors: ÇİLEK Arif , KARAVARDAR Alper
Published: January 2022

Muhasebe dersi en önemli ve öğrenciler açısından en çok güçlük çekilen derslerden bir tanesidir. Bu çalışma “Genel Muhasebe” dersini alan Giresun Üniversitesi, Bulancak Kadir Karabaş Uygulamalı Bilimler Yüksekokulu’nda Uluslararası Ticaret ve Finansman Bölümü öğrencilerinin derse yönelik bakış açıları hakkında bilgi edinmeyi amaçlamaktadır. Çalışmanın verilerinin elde etmek için Duman, Apak ve Yücenurşen (2015) tarafından yapılan 5’li likert ölçeği temel alınarak oluşturulan anket formu ve cevaplayıcıların demografik özelliklerinin belirleyen bilgi formundan yararlanılarak 208 öğrenciye anket uygulanmıştır. Çalışma bulguları ilk olarak frekans dağılımları ve yüzdelik bazda değerlendirilmiştir. Sonraki aşamada faktör analizi sonucunda 21 adet yargı ifadesi 7 faktör altında sınıflandırılmıştır. Bu yargılar ile ilgili faktörler özgüven, kaygı, istek, belirsizlik, önyargı, heyecan ve gereklilik olarak ifade edilmiştir. Son olarak demografik özellikler ile muhasebe dersi ile ilgili yargılar arasındaki ilişkilere yönelik Ki-kare testi yapılmıştır. Ki-kare testi bulgularına göre genel olarak “Mezuniyet sonrası kariyerim için endişe duymaktayım”, “Muhasebe anlayışının beni daha üretken bir birey yapacağını düşünüyorum”, “İnsanlar motive edildiğinde muhasebe bilgi sistemlerini uygulamayı öğrenebilir ve uygulayabilir” ve “Muhasebe öğrenme yeni bir beceridir, ne kadar pratik yaparsanız o kadar iyi hale gelirsiniz” yargıları anlamlı sonuçlar ortaya koyarken, “Muhasebe öğrenmenin zorluğu heyecan vericidir”, “Muhasebe sistemlerinin nasıl işlediğini anlamakta güçlük çekiyorum” ve “Finansal tablo hazırlama, analiz etme ve yorumlama becerim konusunda güvende değilim” yargıları anlamlı sonuçlar ortaya ortaya koymamıştır.
AVRUPA İNSAN HAKLARI MAHKEMESİNİN YENİ MEDYADA İFADE ÖZGÜRLÜĞÜ İÇTİHADI
Authors: ERKAL Abdi
Published: January 2022

Günümüzün çağdaş demokrasilerinde ifade özgürlüğü, toplumların ilerlemesini sağlayan vazgeçilmez haklardan biri olarak görülmektedir. İletişim alanında yaşanan teknolojik gelişmelerle beraber ifade özgürlüğü, etkileri ülke sınırlarını aşan ve bugün yeni medya adını verdiğimiz kitle iletişim araçları üzerinden kullanılmaya başlanmıştır. Bu durum bir yandan kitle iletişiminin etkisini artırırken diğer yandan da bu ortamlarda ifade özgürlüğünün nasıl kullanılacağı, bu hakkın kapsamının ve sınırlarının neler olacağı konusunu tüm dünyanın gündemine taşımıştır. Yeni medya farklı aygıt ve tekniklerle etkisini hızla artırırken hukuk kuralları bu ortamda kullanılan özgürlüklerin kapsam ve sınırlarını aynı hızla belirleyememektedir. Buna her ülkenin kendi hukuk sitemindeki farklı uygulamaları da eklendiğinde yeni medyada ifade özgürlüğünün kapsam ve sınırlılığının belirlenmesi için dünyanın en etkili mahkemelerinden Avrupa İnsan Hakları Mahkemesinin ilgili içtihatları incelenmiştir. Çalışmamızda konuyla ilgili tüm hukuki metinler içerik çözümlemesi yoluyla incelenmiş ve bu alanın kapsamı ile sınırlarının belirlenmesi amaçlanmıştır. Eldeki verileri değerlendirdiğimizde mahkemenin yargılamalarında yeni medyayı fiziki dünyadan bağımsız gördüğü ve yeni medyayı kendi özellikleri içinde inceleyip kararlarını da bu yönde vermeye çalıştığı görülmektedir. Ayrıca mahkemenin verdiği kararlar, yeni medyada ifade özgürlüğünün korunması için devletler ve ulusal yargı organları dışında gazeteciler ve yeni medya kullanıcılarına da sorumluluklar yüklemektedir.
EXAMINING PROFILE OF ENTREPRENEURS BENEFIT FROM KOSGEB NEW ENTREPRENEUR SUPPORT IN TRA2 REGION
Authors: ŞENEL Kutay , GENÇ Kurtuluş Yılmaz
Published: January 2022

Entrepreneurs have an important role in the development of countries' economies. Entrepreneurs who contribute to the increase in economic prosperity, employment and added value in the society should be supported. In addition to the support mechanisms that affect the success of enterprises, the characteristics of entrepreneurship are also important. The purpose of this study is to determine the profile of entrepreneurs who have established businesses in the TRA2 Region by benefiting from the KOSGEB New Entrepreneur Support Program. The sample of the study consists of 102 entrepreneurs benefiting from New Entrepreneur Support in the TRA2 Region. According to the findings, it was concluded that the participants were predominantly male and married individuals, their average age was 39 (± 8.5 months) and they had high school and below education. The male dominance of entrepreneurs in the TRA2 region is also compatible with the general entrepreneurial profile of Turkey.The characteristics of entrepreneurs affect the performance of their businesses. In TRA2 region, it was determined that demographic characteristics such as age, gender and marital status have a low effect, personal development factors such as work experience, education and culture have a high effect on the formation of the entrepreneurial personality of individuals. While the most important advantage of being an entrepreneur for the participants is the feeling of achievement, the biggest disadvantage is the burden of responsibility. It was concluded that the most important feature to be an entrepreneur is to have an entrepreneurial spirit. In addition, it can be said that the most important obstacle to entrepreneurship in the TRA2 region is the problem of financing. Supporting entrepreneurs will contribute to the increase in the number of entrepreneurs who create added value and to reduce the employment problem.
Endonasal Endoscopic and Transoral Approaches to the Craniovertebral Junction and the Clival Region
Authors: Piloto Orestes López , Hernández Tania Cruz , Jiménez Pedro Domínguez , Rodríguez de la Paz Norbery , Abreu Casa Duniel , Martínez Valdes Lismary
Published: January 2022

Introduction: The transoral approach was first described by Kanavel in 1917 to treat injuries of the craniospinal junction. In 2002, Frempong-Boaudu reported 7 adults who underwent endoscopically assisted transoral surgery, this was the first report that endoscope was used in an assisted manner for transoral surgery. In 2005, Kassam published the first report of an EEA being used to perform an odontoidectomy. Method: A descriptive, retrospective and linear study was carried out in 16 patients who underwent surgery using the microsurgical and endoscopic transoral and Extended Endoscopic Endonasal approach in the period from January 2004 to May 2021. Results: The average age of the patients was 45 years and there was a predominance of the male sex (10) with the female one (6). The tumoral pathology (9), 6 cases with histological diagnosis of clivus cordroma and 1 patient with chondrosarcoma, two cases with Meningioma and cholesterol granuloma of clival localization, achieving gross total resection in 2 of them and in the rest subtotal resection, all improved neurological symptoms. Complications, partial dehiscence of the velopalatine surgical wound 1 case, 1 lesion of the left vertebral artery and 1 case decompensated Diabetes Mellitus and hemoneumothorax during stay in the ICU, which death 7 days after surgery and 1 CSF fistula. Conclusions: Both, the transoral and endonasal endoscopic approaches have their precise indications in each particular case, having their indications well defined. To achieve this, we must have neuroimaging studies and be able to correctly define the selection of the surgical approach.
Etıology and Management of Lower Gastroıntestınal Bleedıng ın Neonates: A Revıew Artıcle
Authors: Erikci Volkan Sarper
Published: January 2022

Lower gastrointestinal bleeding (LGIB) in neonates is occasionally encountered in clinical practice. There are various causative factors prodicing LGIB in neonates and the babies are usually managed with regard to the underlying pathology that produces LGIB. Although majority of these bleeding episodes is self limited, certain neonates with LGIB may necessitate prompt management including urgent surgical intervention. In this review article it is aimed to review the etiology, epidemiology, clinical manifestations and principles of treatment of LGIB in neonates under the light of relevant literature.
Design, Formulation and Physicochemical Evaluation of Clotrimazole Chewing Gum
Authors: Aslani Abolfazl , Karbasizadeh Esfahani Shekofeh
Published: January 2022

Background: Oral candidiasis is widespread in the patients with immunodeficiency diseases. Chewing gums are considered as mobile drug delivery systems that affected locally or systemically via the oral cavity. This study aimed to develop and evaluate the formulation of clotrimazole chewing gums for patients having oral candidiasis. Materials and Methods: Fourteen formulations (F) were designed by Design-Expert, version 7. These formulations were different in the amount of gum bases and sweeteners. Gum bases of elvasti, 487, stick, and fruit C were heated up to 70°C. Clotrimazole powder, sugar, liquid glucose, glycerin, mannitol, xylitol, and maltitol as well as different flavoring agents were added to the gum bases at 40°C. Content and weight uniformity, organoleptic properties evaluation, releasing the active ingredient in the phosphate buffer pH, 6.8, and taste evaluation were analyzed by Latin square analysis. Also, the mechanical test was done on F13 and F14 formulations. Results: F14 was the best formulation in terms of organoleptic properties. This formulation had suitable size, hardness, softness, and lack of adhesion to teeth. F14 formulation released 89% and 97% of clotrimazole after 30 and 45 minutes, respectively. F14 content uniformity and weight variations were 9.83±0.086 mg and 1.14±0.09 g, respectively. F14 evaluation of mechanical properties showed Young’s modulus about 0.32 MPa, and yield point occurred at the stress of 0.599 MPa and strain of 4.1%. Conclusion: F14 was chosen according to its physicochemical and organoleptic properties. F14 had adequate hardness, lack of adhesion to the teeth, suitable size, and best drug release. Tutti Frutti was a proper flavoring agent for clotrimazole gum formulations.[GMJ.2021;10:e1084]
Geographic Stomatitis with Multiple Areas Involvement of Oral Cavity: A Case Report and Review of Literatures
Authors: Abbasi Farid , Sehatpour Aliyeh , Sajedi Seyed Masoud , Bahadori Parisa , Nouri Mohadeseh
Published: January 2022

Background: Geographic stomatitis is an uncommon migratory benign lesion of oral mucosa with unknown etiology. It can affect all the areas of the oral mucosa, but the dorsum and lateral borders of the tongue are the most commonly involved areas called geographic tongue. The clinical appearance of this condition is the oval or circular erythematous areas with irregular elevated keratotic borders. These characteristic features of geographic stomatitis are diagnostic for all clinicians when appearing on the dorsum of the tongue, despite other affected areas of oral mucosa that can confuse clinicians. This condition may be associated with some diseases such as psoriasis, Reiter’s syndrome, and atopic conditions, so the clinicians should rule out these diseases and diagnose the geographic stomatitis. Case Report: A 17-year-old male attended to our department for a routine dentistry checkup. During the intraoral examination, we found multiple erythematous areas surrounded by a thin white border on different surfaces of his oral cavity. His extraoral examinations were completely normal. Conclusion: Due to the rarity of this lesion on the other sites of oral mucosa rather than dorsum and lateral borders of the tongue such as labial mucosa, buccal mucosa, the floor of the mouth, ventral surface of the tongue, and palate, it is necessary to report, study and evaluate each case of this condition that clinicopathologic findings have confirmed this diagnosis, to treat and advice these patients on the best approach. [GMJ.2021;10:e2071]
Long Noncoding RNAs-LET Behave as a Noncoding Signature for Early-Onset Menarche and Late-Onset Menopause in Breast Cancer Patients
Authors: Darbeheshti Farzaneh , Mansoori Hosein , Abdollahzadeh Rasoul , Dastsooz Hassan , Daraei Abdolreza , Mokhtari Maral , Salmani Hamzeh , Davood Abadi Farahani Mostafa , Tahmasebi Sedigheh , Mansoori Yaser
Published: January 2022

Background: Breast cancer (BC) as a major cause of cancer-related death in women shows a very complex molecular and clinical phenotype, which has reduced the effectiveness of medical interventions. Evidence suggests that long noncoding RNAs (lncRNAs) are responsible for an important part of this complexity. This study aims to assess the expression and clinical implication of lncRNA LET in the pathobiology of BC. Materials and Methods: Quantitative real-time polymerase chain reaction was used to measure the expression of lncRNA-LET in breast tumors and adjacent normal-appearing tissues from 4 BC patients, as well as normal mammary tissues. Moreover, a bioinformatics approach was applied to uncover the potential lncRNA-LET-mediated sponge regulatory network as LET/miRNA/mRNA crosstalk. Results: Our study revealed that lncRNA-LET was significantly down-expressed not only in breast tumors but also in normal appearing breast tissues samples from BC subjects compared with true normal breast tissues obtained from healthy women. The low level of lncRNA-LET was meaningfully associated with early-onset menarche (≤13 years) and late-onset menopause (≥50) in patients. Moreover, the bioinformatics analyses support that lncRNA-LET could function as a tumor suppressor miRNA sponge. Conclusion: The results indicate that normal appearing breast tissues can undergo tumor-related molecular changes. Furthermore, they reveal the potential role of the dysregulation in LET-mediated ceRNA network in the pathophysiology of BC.
Review On the Effects Curcumin on Tumors of the Reproductive System
Authors: Moradi Zahra , Hekmatnia Yasaman , Dalili Amin , Sadeghi Mostafa , Neshat Seyed Sina , Jamalnia Sheida , Tohidian Mostafa , Reihani Elnaz
Published: January 2022

Curcumin, a polyphenolic derivative of Curcuma longa rhizome, has numerous beneficial effects, including antibacterial, anti-inflammatory, antiviral, antioxidant, antifungal, anti-ischemic, anti-cancer, hypoglycemic, nephroprotective, antirheumatic, hepato-protective, and antimutagenic. Curcumin has indicated the capability to exert anti-cancer activity by multifunctional mechanisms, such as induction of apoptosis, inhibition of cancer cell proliferation, cell cycle regulation, chemotherapeutic intestinal absorption, and modification of several cancer cell types signaling pathways. Several studies have shown that curcumin may have protective effects against tumors of the reproductive system. Reproductive system cancers may cause many undesirable physical and, especially, mental disorders. Infertility and its mental consequences, sexual problems, chemotherapy and surgery-related adverse effects, substantial economic burden, and death are the most common complications regarding the cancers of the reproductive system. By modulating several reproductive cancer hallmarks such as signaling pathways, multiple drug resistance, cancer cell growth and proliferation, tumor angiogenesis, and transcription factors, curcumin could be used as a safe, non-toxic, cheap, and easily accessible drug for treating different types of reproductive cancers. [GMJ.2021;10:e2178]
Comparison of Mental Health Status between Two Periods during Coronavirus Disease 2019 Pandemic in Iranian Adult Population
Authors: Mani Arash , Estedlal AliReza , Akbary Ali , Estedlal Taraneh , Ouladinejad-Rodbali Sara , Shahabi Saeed , Ghaemi Seyede-Zahra , Zarei Leila , Heydari Seyed-Taghi , Bagheri-Lankarani Kamran
Published: January 2022

Background: One unprecedented year after the coronavirus disease 2019 (COVID-19), the pandemic is no longer a short-term stressor; the unremitting/chronic effects of COVID-19 disease is likely to cause impaired physical and mental health upon population and the implemented public health and social measures to limit transmission and reduce mortality and morbidity from COVID-19 expose many people to social isolation, job loss, and economic recession. This study aims to compare mental status and four mental symptoms (somatization, anxiety, depression, and social functions) between two periods during the first year of the COVID-19 pandemic. Materials and Methods: Current study consists of two cross-sectional mental health surveys on the Iranian adult population carried out in two periods of March to April 2020 and December 2020 to February 2021 in two important Provinces of Iran (Fars and Khorasan Razavi). In the first survey, 1337 individuals participated in the study and completed the General Health Questionnaire-28, while in the second survey, 1205 participants completed the same questionnaire. Results: Among 1337 participants of the first survey, there were 876 (65.5%) females and 461 (34.5%) males with an average age of 37.41±10.58 years. In the second survey, there were 1205 participants with mean age of 33.79±19.57 years. The rates of females and males were 57.7% and 42.3%, respectively. Compared to the first survey, the second one showed that poor mental health condition that was 1.40 (95% confidence interval: 1.17-1.67) times higher based on the age, sex, education, marital status, economic, alcohol, cigarette, water-pipe, and sedative (P<0.001). Conclusion: Poor mental health status has increased during the first year of the COVID-19 pandemic. These results revealed that the COVID-19 pandemic was a chronic stressor faced by people every day; therefore, more robust mental health-related considerations must be implemented. [GMJ.2021;10:e2199]
Major Dietary Patterns Are Associated with Acute Ischemic Stroke
Authors: Tabrizi Reza , Keshani Parisa , Jalali Mohammad , Estakhr Mehrdad , Sarihi Sorour , Kheirmandparizi Maryam , Azarpazhooh Reza , Borhani-Haghighi Afshin
Published: January 2022

Background: Dietary patterns play an essential role in vascular diseases; however, the association of specific dietary patterns and the risk of stroke is unknown. We designed the current study to evaluate several dietary patterns and their association with ischemic stroke. Materials and Methods: This case-control study was performed on 300 subjects, including 150 cases with ischemic stroke admitted to a tertiary referral center in Shiraz, Southern Iran, and 150 age- and sex-matched stroke-free individuals as controls. Using a 62-item Simple Stroke Food Frequency Questionnaire (SS-FFQ), we collected data regarding the dietary habits of all the participants. We extracted the major dietary patterns via principal component analysis using the varimax rotation technique with Kaiser Normalization. Finally, adherence to dietary patterns among the participants was divided into quartiles. We investigated the association between dietary patterns and ischemic stroke using multiple logistic regression analyses. Results: One-hundred and fifty ischemic stroke patients (91 males and 59 females, mean age of 63.9±16.04 years) and 150 age- and sex-matched controls (91 males and 59 females, mean age of 61.99±16.04 years) were included. After adjusting five major dietary patterns for vascular risk factors, we found that diets rich in fibers and plant-based proteins (P<0.001) and micronutrients (P<0.001) had a lower odds of ischemic stroke as compared to high-fat proteins (P=0.003) and empty calories (P<0.001) diets, but consuming healthy animal proteins (P=0.115) had no effects on the occurrence of ischemic stroke.  Conclusion: Based on our study, we suggest that fibers and plant-based proteins, and micronutrient diets could reduce the odds of stroke, so public awareness about the effects of different dietary patterns should be raised.
THE EFFECT OF PRE-PLANTING TREATMENT OF SEEDLINGS WITH BACTERIAL STRAINS ON THE VEGETATIVE REPRODUCTION OF GARDEN STRAWBERRIES
Authors: Belyaev A. A. , Shakhristova A. A.
Published: January 2022

In field experiments of the strawberry queen bee, it was found that pre-planting treatment of the root system of seedlings with bacterial biopreparation Phytop 8.67, at a concentration of 1×105 CFU/ml, as well as its tank mixture with humic preparation Phoenix, 0.05% gave the greatest efficiency – stimulation of vegetative reproduction of plants by 3.9-4.9 rosettes /plant (by 24-32 %) relative to control was observed. At the same time, it should be noted that the effect of the tank mixture Phytop 8.67, 1×105 CFU/ml + Phoenix, 0.05 % statistically significantly (P<0.05) exceeded all other options for stimulating vegetative reproduction of plants.
INTRODUCTION OF NEW VARIETIES OF LARGE-FRUITED REMONTANT STRAWBERRIES IN THE FOREST-STEPPE OF WESTERN SIBERIA
Authors: Makarova K. S. , Pastukhova A. V. , Gazizulina A. S. , Petrov A. F. , Zenkova A. A. , Petruk V. A.
Published: January 2022

The authors presented the results of the influence of stress factors on the yield of garden strawberry remontant large-fruited. Phenological and morphological observations, recording and evaluating the quality of the obtained fruits were carried out during the research. Varieties of remontant strawberries with a complex of economically beneficial features were identified. There were features as high yield, winter hardiness, resistance to major diseases and pests were presented. The obtained data confirmed that the highest productivity per bush showed varieties bearing fruit during the entire growing season: Selva - 376.06g, Vima Rina - 411.27g, Remontant large-fruited (hybrid) - 425.42g.
PUBLICATION OF RUSSIAN LITERATURE ON THE DEVELOPMENT OF THE AGRARIAN ECONOMY AND FISHERIES IN ANCIENT SOCIETIES OF “BARBARIAN” EUROPE: MID-XIX CENTURY. – 1950 S.
Authors: Erlikh V. A.
Published: January 2022

The authors presented an article on the publication of printed matter covering the history of agricultural economy and trades in Central, Northern, Northwestern, and Southwestern Europe in antiquity. The report is based on editions of Russian-language literature published in Russia in the mid-19th century - the 1950s.
ONTOGENETIC, BREED, AND SEASONAL FEATURES OF THE SYNTHESIS OF THYROXIN AND CORTISOL IN DOGS AND CATS
Authors: Efanova N. V. , Batalova S. V. , Osina L. M. , Naumova Е. D.
Published: January 2022

The article presents data on the breed and seasonal characteristics of the synthesis of thyroxine and cortisol in dogs of different breeds and cats that do not have a breed. It has been shown that the synthesis of thyroxine in dogs and cats depends on the breed, age and season. The functional activity of the thyroid gland in dogs decreases by 10-12, and in cats by 9-13 years of age. The highest level of thyroxine production throughout the entire research period belongs to the Griffon Petit-Brabancons. The synthesis of cortisol in dogs and cats is stable and does not undergo statistically significant changes. Seasonal dynamics of thyroxine is observed in dogs, but absent in cats. No sea-sonal dependence of cortisol synthesis has been reported in dogs and cats.
PRODUCTION TECHNOLOGY OF FRUIT-FILLED COTTAGE CHEESE FOR BABY FOOD OVER 6 MONTHS OF AGE
Authors: Boyarshinova E. V.
Published: January 2022

Currently, cottage cheese is one of the leading dairy products for infants’ nutrition. Today, the urgent task is to expand the range of sour-milk products by developing a technology for cottage cheese production with the addition of a fruit filler. The object of research is cottage cheese for the diet of children over six months. The cottage cheese is produced from whole milk subjected to high-temperature treatment with the use of starter microorganisms and with the addition of fruit filler “Banana”. The children’s curd recipe developed by the authors included the following raw materials and components: milk with the mass fraction of fat 3.4 %, skim milk with the mass fraction of fat 0.05 %, direct injection starter Flora C-170, fruit filler “Banana”. Production technology included the following stages: receiving and preparing raw materials, normalization of milk, homogenization, pasteurization and cooling of the normalized mixture, fermentation, ultrafiltration of curd clot, cooling and ripening of the product. The authors conducted laboratory studies of cottage cheese to assess the quality and safety of the resulting product. The products meet the requirements of GOST 32927-2014 for organoleptic indicators: taste and smell, appearance and consistency, colour. The products also meet the needs of the Technical Regulations of the Customs Union (TR CU) 033/2013 “On safety of milk and dairy products” in terms of microbiological and antibiotic content.
METHOD TO IMPROVE THE CONSUMER QUALITY AND ENVIRONMENTAL SAFETY OF QUAIL MEAT DURING DENITRIFICATION
Authors: Gaitov Ch. R. , Chabaev M. G. , Gappoeva V. S. , Baeva A. A. , Dzhaboeva A. S. , Gadzaonov R. H.
Published: January 2022

Phospholipids are a kind of “solvents” of cholesterol and show a hepatoprotective effect. Also, phospholipids regulate fat and carbohydrate metabolism, improve the functional activity of the liver and its detoxification function. The study aims to study the impact of different doses of phos-pholipid lecithin preparation on economically useful indicators, meat productivity, nutritional value and environmental safety of quail meat at a subtoxic dose of nitrates in their compound feed. This article presents materials that indicate the feasibility of introducing phospholipid preparation of lecithin in the amount of 1.0 % by weight of feed under the presence of a sub-toxic dose of nitrates in the compound feed quail grown for meat. This introduction of phospholipid preparation of lecithin increases the preservation of livestock, body weight gain and reduces the cost of feed per unit gain. Poultry of the 2nd experimental group had an advantage over their control counterparts in preservation rate by 4.0 % and average daily growth by 9.50 % (P<0.05). The authors observed the benefit over the control samples in the concentration of dry substances by 0.98 and 0.99 %, protein by 0.98 and 0.97 % (P<0.05) in the examples of thigh and breast muscles of the poultry of the 2nd experimental group. The value of the protein-quality index (PQI) was higher by 13,55 % (P<0,05) in the samples of white meat from poultry carcasses of the 2nd experimental group as compared with the control counterparts. Also, the examples of poultry meat of the 2nd experimental group had better sanitary and hygienic characteristics. For instance, they had 36.83 % lower nitrate content (P<0.05) and 40.91 % lower nitrites content (P<0.05). This content indicates high denitrifying properties of phospholipid lecithin.
METHOD OF INCREASING MEAT PRODUCTIVITY AND ENVIRONMENTAL SAFETY OF BROILER MEAT BY FEEDING ADSORBENT AND ANTIOXIDANT
Authors: Kovaleva Yu. I. , Abdulkhalikov R. Z. , Ktsoeva I. I. , Temiraev R. B. , Vityuk L. A. , Gadzaonov R. H.
Published: January 2022

In recent years, the use of adsorbent and antioxidant preparations in the formulation of feed with a high content of heavy metals is a promising direction in the industrial production of broiler meat. The study aims to study the consumer and hygienic properties of broiler meat when including adsorbent Ferrotsin and antioxidant Selenopyran in diets with high heavy metals and aflatoxin B 1 content. The authors experimentally established the necessity of containing the adsorbent Ferrotsin in the dose of 300 g/t feed and the antioxidant Selenopyran in the quantity of 300 g/t feed into the composition of mixed fodder with excessive concentration of heavy metals. This inclusion of adsorbents and antioxidants in the compound feed composition is necessary to increase the nutritional properties and protective properties of poultry meat. Group 3 broiler chickens significantly exceeded (P < 0.05) the control counterparts by 18.88 % by weight of half-gutted carcass and 18.26 % by weight of the gutted carcass. Also, broiler chickens of the 3rd experimental group exceeded the content of solids in the thoracic and thigh muscles by 1,40 and 0,60, and protein by 0,67 % and 0,67 %. Group 3 broilers significantly (P < 0.05) exceeded the control in protein quality index (PQI) of meat by 18.86 %. In broilers of experimental group 3, there was a reliable (P < 0.05) decrease in the level of zinc by 3.07, cadmium by 2.25 and lead by 3.24 times in the samples of breast muscle relative to the control counterparts. The highest final score was obtained by boiled white poultry meat of the 3rd experimental group. This sample of meat reliably (P < 0.05) exceeded the total sum of organoleptic parameters of the control sample by 0.81 points. In broilers of experimental group 3 in examples of breast, thigh muscles and meat homogenate, the level of selenium was significantly higher than in control due to the presence of this substance in Selenopyran.
EFFECTS OF LEAD AND CADMIUM INTOXICATION ON ANTIOXIDANT STATUS OF BROILER CHICKENS AND ITS CORRECTION WITH SYNTHETIC PREPARATIONS
Authors: Koval Yu. I.
Published: January 2022

The authors present the results of a study of the effects of long-term (1.5 MPa) and short-term (5, 10 and 15 MPa) intoxication with heavy metals on the antioxidant status of broiler chickens. The authors found that the addition of increased concentrations of toxicants to the diet leads to their accumulation in poultry’s muscle, fat tissues, and skin. According to the study, lead content increases by 2.25 times, cadmium content increases by 6.5 times. Lipophilic compounds Tiofan and Tiofan M have the most pronounced detoxifying effect in chronic intoxication. Fantox 11-1 is the most pronounced detoxifying effect among hydrophilic compounds, which are inferior to lipophilic ones. Accumulation of heavy metals in the body led to a decrease in the antioxidant status of poultry. There was an acceleration of oxidative processes in long-term experimental toxicosis up to 3.10, up to 21.00 times in the short-term. The addition of 100 mg of lipophilic antioxidants per 1 kg of live weight to the diet with 7.5 mg of lead and 0.75 mg of cadmium per 1 kg of feed resulted in a decrease in the rate of oxidation reactions. The presence of lead and cadmium ions in the tissues of poultry caused a reduction of induction periods in the temperature-stabilized samples to 90 %. Enrichment of the diet with Thiophan and Fantox 11-1 increased this indicator up to 12.40 times. The hydrophilic antioxidant Fantox 11-1 dosage of 15 mg per 1 kg of live weight had a pronounced effect. Its introduction into the diet will correct the lack of endogenous antioxidants and increase the body’s antioxidant status under the influence of heavy metals.
STRESS-RESISTANT OF PUREBRED AND CROSSBRED PIGS OF DIFFERENT BRED COMBINATIONS
Authors: Bekenev V. A. , Frolova V. I. , Bolshakova I. V. , Frolova Yu. V. , Deeva V. S. , Ites Yu. V.
Published: January 2022

The authors presented the results of experimental studies on the stress-resistant of pigs. The first group is a breed created in Sapphire Ltd. This breed is a breeding group (BG) in purebred breeding and their mixtures in two- and three-breed combinations with Landrace (L) and Duroc (D) boars under conditions of industrial farm technology in Siberia. Two methods assessed stress-resistant of piglets of different breed groups. The first method is “weaning crisis”. The second method is a com-parison of cortisol levels in the blood. Three-breed weanling piglets (SGxL)xD turned out to be the most stress-sensitive. Stress-resistant piglets had an effect on their growth during the rearing period. During this period, stress-resistant animals of all breed combinations had higher average daily gain than stress-sensitive animals (P < 0.001). Stress-resistant animals of the breeding group (SG) showed an average daily growth of 547.5 g during the fattening period. Also, the stress-resistant animals of the breeding group reliably surpassed the stress-sensitive pigs by 461.4 g (P < 0.01), the two-breed pigs by 455.9 g and 404.7 g and the three-breed pigs 451.8 g and 419.2 g, respectively. There was a statistically significant advantage in the indices of the average daily gain among the purebred young-sters of the breeding group (SG) (543 g) compared to the two-breed pigs (447g) and the three-breed pigs (402g), i. e., by 17.8 % and 26 % at P < 0.001. The authors found that the EAAcr/- genotype in stress-sensitive pigs was more common than EAA-/(0.71 ± 0.07 vs 0.48 ± 0.09). Stress-resistant pigs of the breeding group (SG) with EAE edg/edf blood group genotypes were characterized by increased growth intensity and reliable superiority over stress-sensitive pigs. The authors believe that these genotypes can be accepted as preliminary candidates for genetic markers of stress resistant. Blood cortisol levels appeared to be unrelated to stress-resistant compared to the “weaning crisis” method. This relationship (blood cortisol level with stress-resistant) applies to all studied breed combinations, both individually and as a whole.
The usage of personalized scheme of fentanyl administration during coronary artery stenting
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine, Dziuba D.О.
Published: January 2022

The aim – to develop a personalized scheme of fentanyl administrationfor coronary artery stenting. Materials and methods. Ninety patients with ischemic heart disease who underwent planned stenting of the coronary arteries were studied. The patients who underwent surgery were evenly divided into three study groups, depending on mode of the intraoperative analgesic sedation and the approaches to anesthesia. The first comparison group consisted of patients who received slow intravenous administration of diazepam and fentanyl solutions. The second comparison group consisted of patients with balanced administration of fentanyl and propofol solutions to provide analgesic sedation at the level of conscious anesthesia. The study group consisted of patients with a personalized approach to the administration of opiates, namely, we used the original fentanyl test described in the article. Analgesic sedation at the level of conscious anesthesia (ІІІ by Ramsey) was maintained by propofol infusion. Results. The usage of a personalized scheme of fentanyl administration for stenting of the coronary arteries, compared to the standard sedation using combination of diazepam and fentanyl, was accompanied by better indicators of intraoperative blood saturation with oxygen and carbon dioxide (respectively (103.67 ± 22.05) and (39.64 ± 6.85) mm Hg in group 1, (105.70 ± 31.64) and (37.68 ± 7.11) in group 2 and (109.42 ± 34.36) and (36.25 ± 6.52) mm Hg in patients of the 3rd group), lower blood pressure after surgery ((127.85 ± 9.87)/(79.64 ± 8.62) mm Hg in patients of group 1, (129.48 ± 8.73)/(81.05 ± 7.92) mm Hg in group 2 and (131.15 ± 10.64)/(82.68 ± 9.72) mm Hg in group 3), lower level of stress markers (blood cortisol during surgery in patients of the 1st group (8.83 ± 4.58) mmol/L, in patients of the 2nd group – (7.73 ± 2.79) mmol/L, in patients of the 3rd group – (7.55 ± 4.35) mmol/L), as well as lower frequency of detecting episodes of perioperative pain of various origins. Conclusions. A method of personalized anesthesia was elaborated, based on individual scheme of fentanyl administration («fentanyl test») during coronary artery stenting. Its usage is safe (due to the optimal parameters of gas exchange and hemodynamics and fewer side effects, such as nausea and residual sedation) and effective (due to the lower level of stress markers and less frequent complaints of pain of various origins) than when the routine technique was used. Key words: analgesic sedation, individual sensitivity, fentanyl, diazepam, propofol.
Influence of multimodal low-opioid anesthesia on the dynamics of аnnexin V in blood plasma during cardiac surgery
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine, Heart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine, Maruniak S.R. , Loskutov O.A. ,   Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine, Heart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine, Druzhyna O.M. ,   Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine, Heart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine, Malish I.R. ,   Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine, Kyiv City Clinical Hospital for Emergency Medical Care, Kyiv, Ukraine, Korotchuk N.V. ,   Heart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine
Published: January 2022

The aim – to analyze the effect of anesthesia on the dynamics of аnnexin V during coronary artery bypass grafting with сardiopulmonary bypass (CPB), and the dependence of direct clinical results on the expression of аnnexin V. Materials and methods. The study included 30 patients with coronary heart disease who underwent coronary artery bypass grafting with application of 2–3 aortocoronary anastomoses with CPB. According to the anesthetic management, all patients were divided into two groups: the first group (13 patients) – low opioid anesthetic scheme; control group (17 patients) – a standard scheme of anesthetic management. The determination of the level of аnnexin V in the blood was carried out before CPB and after bringing the sternum by enzyme-linked immunosorbent assay. Results. The low-opioid scheme of anesthetic management was associated with significantly (by 1.5 times) lower level of аnnexin V and by 28.38 % lower level of interleukin-6 at the end of the surgery as compared to the standard scheme. A significant negative correlation (r = –0.117, p = 0.523) was found between the levels of аnnexin V and interleukin-6. One-way analysis of variance showed that patients who had low cardiac output syndrome in the postoperative period had a significantly higher level of аnnexin V after CPB (p = 0.001). Conclusions. The use of multimodal low-opioid anesthesia is characterized by relative safety, a sufficient level of analgesia and lower level of аnnexin V compared to the control group. Key words: coronary artery bypass grafting, low-opioid anesthesia, apoptosis, аnnexin V, interleukin-6.
A novel method of treament of ascending aortic aneurysm
Authors:   Heart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine, Demyanchuk V.B. , Pogrebnyak V.V. ,   Heart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine, Kvasha O.I. ,   Heart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine, Todurov B.M. ,   Heart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine, Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine
Published: January 2022

The need for surgical treatment of ascending aortic aneurysms is due to a number of severe complications that occur during the natural course of the disease, such as aortic dissection and rupture. Such interventions show good immediate and long-term treatment outcomes, but they are often accompanied by high blood loss and surgical trauma, which in elderly patients with concomitant pathology can lead to serious cardiac and extracardiac complications and prolongation of treatment in general. We present a technology of external wrapping of the aorta that reduces surgical trauma while maintaining effect of operation. A clinical case of application of this technology in a 63-year-old patient hospitalized to the clinic of the Heart Institute, Ministry of Health of Ukraine, with a diagnosis of aortic insufficiency of the 3rd degree (tricuspid aortic valve), dilatation of the root and ascending aorta, tricuspid insufficiency of the 2nd degree, high pulmonary hypertension, heart failure with reduced left ventricular systolic function. The use of the proposed method has following advantages compared to the established method of fixation of the vascular prosthesis: fixation of the proximal part of the vascular prosthesis is performed using vascular suture material; elimination of the risk of damage to the aortic wall; elimination of the risk of massive bleeding from the aorta at the site of the prosthesis fixation; decreased duration of surgery. Key words: aortic aneurysm, surgical treatment, wrapping of the ascending aorta.
Immediate results of the еndovascular aneurysm repair in abdominal aortic aneurysm patients with an unfavorable proximal neck
Authors:   O.O. Shalimov National Institute of Surgery and Transplantology of NAMS of Ukraine, Kyiv, Ukraine, Furkalo S.M. , Kondratyuk V.A. ,   O.O. Shalimov National Institute of Surgery and Transplantology of NAMS of Ukraine, Kyiv, Ukraine, Vlasenko O.A. ,   O.O. Shalimov National Institute of Surgery and Transplantology of NAMS of Ukraine, Kyiv, Ukraine, Khasyanova I.V. ,   O.O. Shalimov National Institute of Surgery and Transplantology of NAMS of Ukraine, Kyiv, Ukraine, Khohlov A.V. ,   O.O. Shalimov National Institute of Surgery and Transplantology of NAMS of Ukraine, Kyiv, Ukraine, Gindich P.A. ,   O.O. Shalimov National Institute of Surgery and Transplantology of NAMS of Ukraine, Kyiv, Ukraine, Mazanovich I.A. ,   O.O. Shalimov National Institute of Surgery and Transplantology of NAMS of Ukraine, Kyiv, Ukraine, Pustyntsev O.O. ,   O.O. Shalimov National Institute of Surgery and Transplantology of NAMS of Ukraine, Kyiv, Ukraine
Published: January 2022

More than half of the interventions for abdominal aortic aneurysm are performed using endovascular techniques. However, due to the anatomical characteristics of the aorta about 40 % of patients cannot be candidates for еndovascular aneurysm repair (EVAR). Anatomical features that are difficult or unacceptable for stent-graft placement include short or no proximal neck, angular, tapered neck, and vessel diameter that exceeds the existing capabilities of endoprostheses. In cases where traditional surgical correction is not an acceptable option, various technological methods and equipment are used. The observation included 16 consecutive patients with abdominal aortic aneurysm, where EVAR was performed. When analyzing the anatomical characteristics of the aneurysmal sac, 7 (43.7 %) patients were classified as patients with an unfavorable proximal neck of the aneurysm, the so-called «hostile neck». Two EVAR interventions were complex (2 patients with parallel grafts), which made it possible to achieve an increase in the proximal infrarenal zone implantation up to 16–20 mm, and adjuvant or additional endovascular procedures – in our case, implantation of Aptus Heli-FX endoancors in 5 patients. The comparison group consisted of 9 patients with standard aneurysm neck, where standard EVAR procedures were performed. The main anatomical difference in the groups was the length of the aneurysm neck – 9.9 mm and 36.1 mm in groups I and II, respectively (p = 0,0003). EVAR in the groups were carried out without significant complications or fatal cases; in the first group, the duration of the operation (p = 0.01), the amount of contrast (p = 0.03) and the fluoro time (p = 0.01) were significantly increased than in the 2nd group. The postoperative period did not differ between the groups. Conclusions. The use of contemporary technologies allows to significantly expand the indications for EVAR in patients with unfavorable anatomy. Key words: abdominal aortic aneurysm, еndovascular aneurysm repair.