bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimalisasi Operasi Penegakkan Ketertiban dan Disiplin Sebagai Upaya Pencegahan Tindak Pidana yang Dilakukan oleh Anggota Polri
Authors: Olandha Rivo , Bisma Putra Pratama
Published: April 2024

Penelitian ini menganalisis dan mengkaji tentang optimalisasi operasi penegakkan ketertiban dan disiplin sebagai upaya pencegahan tindak pidana yang dilakukan oleh anggota polri dengan studi kasus Pada Subbidprovos Bidpropam Polda Sumbar. Penelitian ini merupakan penelitian hukum normatif bersifat deskriptif  yang mana tujuan utama yang ingin dicapai dalam penelitian ini adalah Mengetahui dan menganalisis Pelaksanaan Operasi Penegakkan Ketertiban dan Disiplin (Opsgaktibplin) yang dilaksanakan Oleh  Subbidprovos Bidpropam Polda Sumbar terhadap anggota Polri Polda Sumbar, Mengetahui dan menganalisis kendala-kendala yang dihadapi dalam Operasi Penegakkan Ketertiban dan Disiplin (Opsgaktibplin) yang dilaksanakan Oleh  Subbidprovos Bidpropam Polda Sumbar dalam pencegahan terhadap anggota polri Polda Sumbar melakukan tindak pidana, dan Mengetahui dan menganalisis Optimalisasi  Operasi Penegakkan Ketertiban dan Disiplin (Opsgaktibplin) yang dilaksanakan Oleh Subbidprovos Bidpropam Polda Sumbar terhadap anggota Polri Polda Sumbar. Penelitian ini menggunakan data-data primer berupa diperoleh melalui pengamatan (observasi) dan penelitian lapangan (field research) dengan melakukan wawancara terhadap aparat anggota Subbidprovos Bidpropam Polda Sumbar yang melaksanakan Operasi Penegakkan Ketertiban dan Disiplin  Pada Polda Sumbar dan jajarannya melakukan tindak pidana dan data sekunder berupa Data sekunder ini diperoleh dari kepustakaan yang berhubungan dengan penelitian yang akan dilakukan, yang terdiri dari bahan hukum primer, bahan hukum sekunder, dan bahan hukum tersier. Penulis menggunakan pendekatan perundang-undangan, konsep, kasus, dan data hasil pelaksanaan Opsgaktibplin pada Subbidprovos Bidpropam Polda Sumbar. Hasil penelitian menunjukkan bahwa Pelaksanaan Opsgaktibplin yang dilakukan Oleh Subbidprovos Bidpropam Polda Sumbar sebagai tindakan untuk mencegah terjadinya pelanggaran disiplin/ tindak pidana yang dilakukan oleh anggota polri meliputi, Pemantauan dan Patroli, Pengamanan, Pemeliharaan tata tertib, Pengawasan belum optimal, sehingga masih terdapat anggota Polri pada Polda Sumbar yang melakukan tindak pidana.
Geographic Accessibility and Completion of Initial Low-Dose CT-Based Lung Cancer Screening in an Urban Safety-Net Population
Authors: Yi Sofia , Rathod Rutu A. , Natchimuthu Vijaya Subbu , Bhalla Sheena , Lee Jessica L. , Browning Travis , Adesina Joyce O. , Do Minh , Balis David , de Wiliams Juana Gamarra , Kitchell Ellen , Santini Noel O. , Johnson David H. , Hamann Heidi A. , Lee Simon J. Craddock , Hughes Amy E. , Gerber David E.
Published: April 2024

Background: Recent modifications to low-dose CT (LDCT)–based lung cancer screening guidelines increase the number of eligible individuals, particularly among racial and ethnic minorities. Because these populations disproportionately live in metropolitan areas, we analyzed the association between travel time and initial LDCT completion within an integrated, urban safety-net health care system. Methods: Using Esri’s StreetMap Premium, OpenStreetMap, and the r5r package in R, we determined projected private vehicle and public transportation travel times between patient residence and the screening facility for LDCT ordered in March 2017 through December 2022 at Parkland Memorial Hospital in Dallas, Texas. We characterized associations between travel time and LDCT completion in univariable and multivariable analyses. We tested these associations in a simulation of 10,000 permutations of private vehicle and public transportation distribution. Results: A total of 2,287 patients were included in the analysis, of whom 1,553 (68%) completed the initial ordered LDCT. Mean age was 63 years, and 73% were underrepresented minorities. Median travel time from patient residence to the LDCT screening facility was 17 minutes by private vehicle and 67 minutes by public transportation. There was a small difference in travel time to the LDCT screening facility by public transportation for patients who completed LDCT versus those who did not (67 vs 66 min, respectively; P=.04) but no difference in travel time by private vehicle for these patients (17 min for both; P=.67). In multivariable analysis, LDCT completion was not associated with projected travel time to the LDCT facility by private vehicle (odds ratio, 1.01; 95% CI, 0.82–1.25) or public transportation (odds ratio, 1.14; 95% CI, 0.89–1.44). Similar results were noted across travel-type permutations. Black individuals were 29% less likely to complete LDCT screening compared with White individuals. Conclusions: In an urban population comprising predominantly underrepresented minorities, projected travel time is not associated with initial LDCT completion in an integrated health care system. Other reasons for differences in LDCT completion warrant investigation.
Mahatma Gandhi y Bertrand Russell dos pensadores para guiar el proceso constitucional chileno a una constitución ecológica.
Authors: Marcone Lo presti Rodolfo
Published: April 2024

En esta breve reflexión quiero recoger el pensamiento de dos grandes filósofos políticos del S.XX. Como Mahatma Gandhi y Bertrand Russell. Los cuales promueven lo mejor del humanismo pacifista del Siglo XX. Lo que propongo es entregar un par de ideas positivas y propositivas para el debate constitucional chileno. Recordando que es imperiosa y necesaria la transformación de nuestras constituciones políticas desde un prisma de la no violencia activa, las virtudes individuales y la ecología.
La necesaria protección de la avifauna urbana, aves insectívoras en particular, a través de la reglamentación municipal. Especial referencia a la ejecución de obras de modificación o rehabilitación urbana
Authors: Díaz Martínez Juan Antonio
Published: April 2024

Cities are witnessing a progressive loss of populations of swifts, martins, swallows and other species of protected insectivorous birds, which have always found suitable nesting grounds in urban environments. The design of modern buildings does not include suitable places for these birds to nest. For their part, the old buildings, when demolished, are replaced by others that no longer have the conditions that the previous ones offered to give them shelter, favoring the destruction of colonies and the production of inconveniences that force them to move. Given the clear impact that this issue has on the urban environment, which is the responsibility of the municipalities, this paper aims to highlight the existing gap between environmental legislation and daily practice fueled by the permissiveness of public powers, to line followed, after legal discussion, propose the adoption of specific regulatory measures, through the mechanisms offered by urban planning and municipal ordinances.

Las ciudades están asistiendo a una pérdida progresiva de las poblaciones de vencejos, aviones, golondrinas y otras especies de aves insectívoras protegidas, que siempre encontraron en los ambientes urbanos unos entornos adecuados para la nidificación. El diseño de los modernos edificios no contempla lugares adecuados para que aniden estas aves. Por su parte, los antiguos inmuebles, al ser demolidos, son sustituidos por otros que ya no disponen de las condiciones que ofrecían los anteriores para darles cobijo, favoreciendo la destrucción de colonias y la producción de molestias que las obligan a desplazarse. Dada la clara incidencia que esta cuestión tiene en el medio ambiente urbano, competencia propia de los municipios, se pretende poner de manifiesto en este trabajo el desfase existente entre la legislación ambiental y la práctica cotidiana alimentada por la permisividad de los poderes públicos, para a renglón seguido, previa discusión jurídica, proponer la adopción de medidas normativas concretas, a través de los mecanismos que ofrecen el planeamiento urbanístico y las ordenanzas municipales.
Religión y el derecho ambiental arraigado en la modernidad occidental
Authors: Poesche Jürgen
Published: April 2024

¿Religión o derecho ambiental arraigado en la modernidad occidental? El colapso en curso del equilibrio del Holoceno demuestra que el derecho ambiental anclado en ideologías arraigadas en la modernidad occidental plantea una amenaza a la supervivencia de la especie humana. Para alcanzar puntos de inflexión es necesario repensar la sustancia y el propósito del derecho ambiental en Occidente. Un camino prometedor a seguir es un retorno a los fundamentos de la familia jurídica romano-germánica (y de la familia del common law) en asuntos relacionados con la protección del equilibrio del Holoceno y la soberanía sobre las tierras (y las aguas asociadas) de las Naciones Indígenas. Debido a que la Iglesia Católica rechaza el evangelio de la prosperidad, el equilibrio del Holoceno estaría protegido tanto por las enseñanzas de la Iglesia Católica (y Apocalipsis 11:18) como por el pensamiento tradicional de las Naciones Indígenas. Un requisito previo para ello es que Occidente se libere de la modernidad occidental con la ayuda de la Filosofía de la Liberación, fortalecida por la Teología de la Liberación Católica, e imponga el imperio del derecho sobre la base de las erudiciones de Francisco de Vitoria.
Las controvertidas interpretaciones del Tribunal Constitucional en torno a la objeción de conciencia del personal sanitario. ¿Derecho fundamental o no?
Authors: Andreu Martínez María Ascensión
Published: April 2024

The legal and social debate that accompanies conscientious objection is one of the most delicate issues that legal systems currently face. Above all, in the elaboration of laws inwhich ethical and legal considerations come together, such as those related to the beginning and end of life and, therefore, in need of extensive parliamentary debate. The recent rulings of the Constitutional Court, in relation to the right of conscientious objection of health personnel in this matter, have revealed aspects such as its legal nature and the excess of the ordinary legislator in regulating it. However, solutions have been adopted for the correct application of the law, such as those of the Autonomous Community of the Region of Murcia in relation to the law regulating euthanasia, which have made it possible to make the right of conscientious objection compatible with the provision of help to die.

El debate jurídico y social que acompaña a la objeción de conciencia es una de las cuestiones más delicadas a las que se enfrentan actualmente los sistemas jurídicos. Sobre todo, en la elaboración de las leyes en las que confluyen consideraciones éticas y jurídicas, como las atinentes al principio y final de la vida y, por ello, necesitadas de un amplio debate parlamentario. Las recientes sentencias del Tribunal Constitucional, en relación al derecho a la objeción de conciencia del personal sanitario en esta materia, han puesto de manifiesto aspectos tales como su naturaleza jurídica y la extralimitación del legislador ordinario al regularlo. No obstante, se han adoptado soluciones para la correcta aplicación de la ley, como las de la Comunidad Autónoma de la Región de Murcia en relación con la ley reguladora de la eutanasia, que han permitido compatibilizar el derecho de objeción de conciencia con la prestación de ayuda para morir.
Performing social advocacy: A critical sociolinguistic analysis of selected songs of Beautiful Nubia
Authors: Okesola Saheed Omotayo
Published: April 2024

This study explores social advocacies in the songs of Segun Akinlolu (aka Beautiful Nubia). The data for the study comprises ten purposively selected songs by the artist. These songs are Seven Lifes, Owuro Lojo (How do you do?), Ma Ba Won So, Baba Mimo, Jangbalajugbu, Ohun Oju Nri, Table Turns, E K'omo L'ede, Small People’s Anthem, and Mind of Your Own. The study blends critical sociolinguistics and discourse historical approach (DHA) of critical discourse studies in data analysis. The analysis shows that through symbolism, imagery, juxtaposition, rhetorical question and irony, Beautiful Nubia prioritizes social advocacies in his songs by enlightening and raising people’s consciousness about patriotism, justice and equity, national courage and resilience, cultural preservation, and linguistic identity. The study concludes that Beautiful Nubia sees music and its performance as public enlightenment undertakings for sociopolitical advancement and societal repositioning.
An Integrated Entropy-Weighted Sum Model Technique for Evaluating the Metrics of Cybersecurity under Uncertainty
Authors: Mohamed Mai , Mohamed Shimaa S. , Ye Jun , Cui Wen-Hua
Published: April 2024

Businesses and organizations handle large amounts of data that may be accessed unauthorized by hackers, so we need to protect this data and other resources from malicious users. Here comes the role of cybersecurity. Cybersecurity is a multidisciplinary field touching on the technical sciences as well as the social and behavioral sciences. Cybersecurity is the result of intelligent cyberattacks. Cybersecurity is crucial to protecting sensitive data stored on any device due to the increasing amount of information. So, this study evaluates cybersecurity using neutrosophic multi-criteria decision-making (MCDM) techniques such as entropy to obtain weight and the weighted sum model (WSM), for ranking and obtaining the best digital footprint of modern organization's cybersecurity. The cybersecurity estimation issue illustrates the validity and great performance of the presented method as (1) its capability to deal with uncertainty phenomena (2) its straightforwardness; and (3) its heightened capacity to discern alternatives. The presented case study shows that the best alternative of this study is A3 which refers to (Digital supply chain risk) as the best one of all alternatives.
Failures and Repairs: An Examination of Software System Failure
Authors: Rahman Shoaib Ur , Arshid Nouman , Ayaz Zulfiqar Ali , Watara Sadia , Iqbal Muhammad Waseem , Ahmad Saleem Zubair , Ali Riasat
Published: April 2024

The central theme of the article is to provide a better knowledge of software system failures and how to assure, maintain, and provide the support software systems that are in production. It includes the results of our search study. We conducted a qualitative analysis of thirty cases: fifteen from public incident reports and fifteen from in-depth interviews with engineers. Understanding and classifying failures as well as their identification, investigation, and mitigation were the main goals of our study. Furthermore, we obtained important analytical insights that are pertinent to the condition of practice as it is now and related problems. It is common for engineers to be unaware of the scaling limitations of the systems they support until those limits are exceeded, and failures have the potential to cascade across a system and cause catastrophic outages.We argue that the difficulties we've discovered may lead to changes in how systems are designed and supported.
ENTREPRENEURSHIP DALAM PELAYANAN GEREJAWI
Authors: Sandiki Reza , Kustiadi Josse
Published: April 2024

Entrepreneurship dianggap sebagai komponen kunci dalam pembangunan ekonomi global, memainkan peran sentral dalam membentuk dan menggerakkan dinamika ekonomi. Wirausaha memperkuat pertumbuhan ekonomi secara global dengan menciptakan peluang bisnis, mengembangkan inovasi, dan menciptakan lapangan kerja, baik dalam sektor bisnis formal maupun informal. Keterlibatan entrepreneur dalam menghadapi tantangan global menunjukkan adaptabilitas dan kemampuan mereka untuk mengeksplorasi dan memanfaatkan peluang baru. Pengembangan entrepreneurship tidak hanya memengaruhi aspek ekonomi tetapi juga berdampak signifikan pada gereja dan dunia kekristenan. Konsep Entrepreneurship Kekristenan, terkait dengan ajaran Rasul Paulus, membuka peluang dan tantangan baru bagi gereja. Paulus dianggap sebagai pelopor yang memperkenalkan gagasan Pastorpreneur, mengintegrasikan aktivitas rohani dengan sikap kewirausahaan dalam menyebarkan Injil dan membangun komunitas kekristenan. Penelitian ini menggunakan metode kualitatif deskriptif melalui studi pustaka untuk menggali konsep entrepreneurship dalam Kisah Para Rasul. Hasilnya menunjukkan bahwa prinsip-prinsip entrepreneurship memberikan dampak signifikan dalam membentuk karakter dan pendekatan pelayanan para misionaris dan pelayan Kristen. Mereka terinspirasi oleh semangat kewirausahaan untuk menjadi adaptif dan responsif terhadap perubahan, menciptakan landasan bagi pelayanan yang relevan dan efektif.
Comparison of the Efficacy of Cognitive Behavioral Therapy and Eye Movement Desensitization and Reprocessing (EMDR) on the Quality of Life in Adolescents with Social Anxiety Disorder
Authors: Moghbeli Farnaz , Bahrami Mohsen , Jafari Davood
Published: April 2024

Objective: The aim of this study was to compare the effectiveness of Cognitive Behavioral Therapy (CBT) and Eye Movement Desensitization and Reprocessing (EMDR) on quality of life in adolescents diagnosed with social anxiety disorder in Karaj. Methods and Materials: The research methodology was a quasi-experimental pretest-posttest design with a control group and a one-month follow-up. The sample included all adolescents visiting the Cultural Clinic in Karaj from February 2021 to May 2021, who were definitively diagnosed with social anxiety disorder by a psychiatrist. Fifty-one individuals were purposively selected and randomly assigned into two experimental groups and one control group (each group consisting of 17 participants). The first and second experimental groups underwent 12 and 8 sessions of CBT and EMDR respectively. The World Health Organization Quality of Life-BREF (WHO-QOL-BREF, 1996) questionnaire was used as the measurement tool. Data analysis was conducted using repeated measures analysis of variance and Bonferroni tests. Findings: Results indicated that both CBT and EMDR interventions significantly improved quality of life scores compared to the control group (p < 0.001), and this effectiveness was maintained during the one-month follow-up period. There was no significant difference between the effectiveness of the two intervention methods in improving quality of life scores (p < 0.001). Conclusion: Therefore, using CBT and EMDR can significantly enhance the quality of life in adolescents suffering from social anxiety disorder.
Prediction of Loneliness Based on Decision-Making Styles in Couples with the Mediation of Social Support
Authors: Jormoze Fatemeh , Ahadi Hasan , Khalatbari Javad
Published: April 2024

Objective: This study aimed to predict feelings of loneliness based on decision-making styles in couples, mediated by social support. Methods and Materials: The research was correlational in nature. The study population consisted of couples attending counseling centers in District Four of Tehran in 2021. The sample size was determined to be 250 individuals, selected through stratified random sampling. Data collection tools included: the Russell Loneliness Scale (1978), the Scott and Bruce Decision-Making Styles Inventory (1995), and the Zimet et al. Social Support Scale (1988). Statistical methods used descriptive statistics, SPSS software, path analysis, t-tests, Sobel test, and PLS software. Findings: The results indicated that rational and intuitive decision-making styles were positively related to social support, while dependent, spontaneous, and avoidant decision-making styles had an inverse relationship with social support. There was a negative relationship between rational and intuitive decision-making styles and feelings of loneliness, and a direct relationship between dependent, spontaneous, and avoidant decision-making styles and feelings of loneliness. Conclusion: Decision-making styles were predictors of feelings of loneliness. Additionally, social support played not only a mediating role but also amplified the relationship between decision-making styles and feelings of loneliness.
Knowledge, Attitude and Practice of Nurses Regarding Therapeutic Communication at Tertiary Care Hospital
Authors: Gul Saher , Saddique Humaira , Jabeen Rubina
Published: April 2024

Background: Effective communication in healthcare settings is pivotal for enhancing patient outcomes and fostering a cooperative environment between patients and healthcare providers. Therapeutic communication specifically plays a crucial role in establishing a rapport between nurses and patients, which can significantly impact the quality of care provided.
Objective: The study aimed to evaluate the knowledge, attitudes, and practices of nurses regarding therapeutic communication within tertiary care hospitals in Lahore, identifying areas for potential improvement.
Methods: A descriptive cross-sectional study was conducted over nine months using a validated questionnaire to assess the knowledge, attitudes, and practices of nurses. A total of 154 nurses were randomly selected using Slovin’s formula for sample size determination. Data collection involved demographic and professional experience details, followed by specific questions on therapeutic communication. The Statistical Package for the Social Sciences (SPSS) Version 25.0 was utilized for data analysis, employing descriptive and inferential statistics to interpret the data.
Results: The results showed that 33.1% of nurses exhibited low knowledge levels, 39.0% moderate, and 27.9% high knowledge about therapeutic communication. Regarding attitudes, 57.1% of nurses displayed a positive attitude while 42.9% had a negative attitude towards therapeutic communication. In practice, 61.7% of nurses demonstrated good practice of therapeutic communication, whereas 38.3% displayed poor practices.
Conclusion: The study concluded that while there is a moderate understanding and positive attitude towards therapeutic communication among nurses, significant portions still require further training and improvement. Enhanced educational programs focusing on therapeutic communication could bridge existing knowledge gaps and refine practices, thereby improving patient care outcomes.
Insight into Retinal Dystrophy: Understanding Features and Treatment Strategies
Authors: Arshad Asma , Alyas Muhammad Aneeq , Arshad Sana , Arshad Usman
Published: April 2024

Retinal dystrophies such as; Retinitis pigmentosa, Congenital Stationary Night Blindness, stargartds disease, lebers congenital amaurosis, and others; present with significant visual impairments due to various genetic mutations affecting retinal function and photoreceptor maintenance. This review explores the diverse landscape of retinal dystrophies, categorizing subtypes based on affected cell types. It sheds light on the clinical characteristics, diagnostic techniques, and complex genetic underpinnings of many illnesses. The study emphasizes the significance of the genetic landscape and enhanced diagnostic tools for prognosis. It also looks at newer forms of treatment, such as gene treatments and pharmaceutical approaches, providing a succinct summary of the developing field. This review, aimed at researchers and clinicians, is a useful tool for comprehending and treating retinal dystrophies.
Comprehensive Outreach: Reach Every Child Initiative Expanded Program on Immunization Khyber Pakhtunkhwa, Pakistan
Authors: Khan Imran , Ameen Ahmed , Anwar Rizwan , Rahman Amjad Ur , Ali Mohammad Wajid , Khan Hafsa , Omair Muhammad , Alam Muhammad Babar
Published: April 2024

Background: Vaccination is one of the most effective public health interventions for preventing infectious diseases. In regions like Khyber Pakhtunkhwa, Pakistan, where access to healthcare is limited, immunization coverage often remains below optimal levels. Targeted outreach activities can play a pivotal role in improving vaccine uptake, particularly in underserved populations.
Objective: This study aimed to assess the effectiveness of immunization outreach activities in increasing vaccine coverage in Khyber Pakhtunkhwa over a defined period.
Methods: A comprehensive methodological approach was utilized involving predefined Excel sheets for daily data collection by trained personnel. Data validation procedures were implemented to ensure accuracy, with regular feedback sessions to improve data collection processes. Monthly reports were compiled and analyzed using SPSS version 25 to summarize immunization activities and coverage rates. The outreach strategy included community announcements and door-to-door campaigns by Local Health Workers (LHWs), designed to identify and vaccinate zero-dose and defaulting children.
Results: The outreach campaign significantly improved immunization coverage, with zero-dose vaccinations achieving 100% coverage. Penta I, II, and III vaccines saw coverage rates of 78.99%, 72.48%, and 78.02%, respectively. Measles vaccines MCV-I and MCV-II achieved coverage rates of 83.01% and 86.11%. The overall strategy effectively reduced gaps in vaccine coverage across various districts.
Conclusion: The study confirms that structured and well-coordinated outreach activities can effectively increase immunization coverage in areas with limited healthcare access. Continuous effort and strategic planning are essential to sustain and build upon these gains to ensure comprehensive vaccine coverage.
Exploring the Neurogenetic Landscape of Autism Spectrum Disorder: The Role of Brain-Derived Neurotrophic Factor (BDNF) Gene in the Complex Web of Neurodevelopment
Authors: Nangdev Pirya , Memon Sameena Gul , Bano Shamshad , Naz Kahaf
Published: April 2024

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with varied manifestations including altered metabolic profiles. Recent research highlights the potential role of Brain-Derived Neurotrophic Factor (BDNF), a hormone derived from adipose tissue, in the pathology of ASD. BDNF levels are reportedly correlated with the severity of autism symptoms, suggesting a link between metabolic dysfunction and the disorder.
Objective: This study aims to deepen the understanding of BDNF levels in individuals with ASD and to explore the implications for diagnosis, treatment, and management of the disorder. It seeks to elucidate the relationship between low BDNF levels and increased autism severity, and to identify potential therapeutic interventions targeting BDNF dysregulation.
Methods: EDTA blood samples (5ml each) from 140 participants (108 with ASD and 32 healthy controls) were collected across various hospitals in Karachi. Plasma serum levels of BDNF were analyzed following a six-month follow-up. A comprehensive statistical analysis was performed, focusing on the relationship between BDNF levels and autism severity, and evaluating diagnostic and therapeutic implications of BDNF dysregulation.
Results: Analysis revealed that lower BDNF serum levels were consistently associated with higher autism severity. Specifically, 60-70% of participants with ASD scored below 8 on the Mini-Mental State Examination (MMSE), indicating significant cognitive impairment. The statistical significance of these findings was confirmed with p-values <0.05.
Conclusion: The study confirms that low BDNF levels are significantly associated with greater severity of autism symptoms, underscoring the importance of metabolic factors in the pathogenesis of ASD. BDNF stands out as a potential biomarker for early ASD diagnosis and personalized treatment strategies. Future Prospects: Future research should aim to delineate the mechanistic relationship between BDNF dysregulation and ASD pathology. Longitudinal studies are needed to assess the long-term effects of BDNF modulation on ASD outcomes and to validate its effectiveness as both a diagnostic and prognostic marker.
Percutaneous Coronary Intervention versus Coronary Artery Bypass Grafting for Chronic Total Occlusion of Coronary Arteries
Authors: Khan Anwar Jamal , Ali Jabar , Safi Shoaib Iqbal , Sajjad Wasim
Published: April 2024

Background: Chronic Total Occlusion (CTO) of coronary arteries presents a significant challenge in the management of coronary artery disease (CAD), influencing treatment outcomes and patient prognosis. Percutaneous Coronary Intervention (PCI) and Coronary Artery Bypass Grafting (CABG) are two predominant revascularization strategies employed, each offering distinct benefits and limitations.
Objective: This study aims to compare the efficacy and safety of PCI and CABG in managing patients with CTO, to inform clinical decision-making and optimize treatment approaches.
Methods: A retrospective analysis was conducted at Lady Reading Hospital, Peshawar, from January 1, 2021, to December 31, 2023. We included 145 patients diagnosed with CTO who underwent PCI (n=65) or CABG (n=80). Data were collected on patient demographics, clinical features, lesion characteristics, procedural details, and follow-up outcomes. Major Adverse Cardiac Events (MACE) and quality of life measures were the primary endpoints. Statistical analysis was performed using SPSS version 25, employing Mann-Whitney U and Chi-square tests for continuous and categorical variables, respectively.
Results: The procedural success rate was 84.6% for PCI and 90% for CABG. MACE occurred in 23.1% of the PCI group and 15% of the CABG group. The average hospitalization duration was 5.8 days for PCI and 8.5 days for CABG. Quality of life assessments showed comparable scores between groups, with PCI scoring 80.6 on the Seattle Angina Questionnaire and CABG scoring 79.8.
Conclusion: PCI and CABG demonstrated similar efficacy and safety profiles in the management of CTO, underscoring the need for individualized treatment strategies based on patient-specific factors. Both methods proved viable, with slightly higher procedural success in CABG and comparable quality of life outcomes.
Evaluation of Epidemiological Risk Features and Hematological Parameters in the Lymphoma Patients in the Larkana Region
Authors: Jesrani Vinay Kumar , Khan Shaista , Lanjwani Abdul Hameed , Mugheri Ishfaque Ahmed , Saira  , Daulat
Published: April 2024

Background: Hodgkin lymphoma (HL) is a type of lymphatic cancer that is distinctly characterized and classified into various subtypes, with varying prognoses based on the stage at diagnosis and treatment modalities. Despite advances in treatment, the specific demographic and clinical factors influencing treatment outcomes and the incidence of side effects, such as chemotherapy-induced anemia and neutropenia, remain under-explored, particularly in diverse regional settings.
Objective: This study aims to evaluate the epidemiological risk features and hematological parameters of lymphoma patients in the Larkana region, with a focus on the impact of chemotherapy on these parameters.
Methods: A case-control study was conducted over twelve months at Linar Hospital in Larkana, involving 40 participants aged between 10 and 70 years. Informed consent was obtained, aligning with ethical standards akin to the Declaration of Helsinki. Two types of blood samples were collected pre- and post-chemotherapy for hematological analysis including total leukocyte count, hemoglobin, and platelet levels, which were assessed using Complete Blood Count (CBC) containers with EDTA. Statistical analysis was performed using Microsoft Excel 2010 and SPSS Version 23, utilizing descriptive statistics and the Student's t-test.
Results: The study documented a decrease in mean hemoglobin levels from 11.42 ± 1.74 g/dL before chemotherapy to 10.65 ± 1.55 g/dL after (p = 0.001), mean white blood cell count from 7.30 ± 2.6 × 10^3/uL to 5.71 ± 2.1 × 10^3/uL (p = 0.003), and platelet count from 297.52 ± 116.2 × 10^3/uL to 230.2 ± 72.6 × 10^3/uL (p = 0.001). These findings indicate a significant hematological impact associated with chemotherapy.
Conclusion: The significant reduction in critical hematological parameters among lymphoma patients’ post-chemotherapy highlights the need for rigorous monitoring and tailored management strategies to mitigate treatment side effects. The findings emphasize the importance of comprehensive patient care and support in improving treatment outcomes in lymphoma.
Phytochemical Profiling and Therapeutic Potential of Ficus benjamina L.: Insights into Anticancer and Anti-inflammatory Activities
Authors: Khan Farzana , Afzal Samina , Khursheed Anjum , Saeed Benish , Zahra Sunder , Majeed Huma , Sarwar Sumreen , Qureshi Muhammad sheraz , Qureshi Muhammad Saleem , Qureshi Muhammad Imran , Abid Hafiz Muhammad Usman
Published: April 2024

Background: Ficus benjamina L., commonly known as the weeping fig, is a plant traditionally used for various medicinal purposes, particularly in Southeast Asia. Despite its widespread use, there is a scarcity of scientific data validating its therapeutic properties, especially its anti-inflammatory and anticancer potentials.
Objective: This study aimed to investigate the phytochemical profile of Ficus benjamina L. and to evaluate its anticancer and anti-inflammatory activities to provide a scientific basis for its traditional uses.
Methods: The plant materials were collected and subjected to extraction using methanol and dichloromethane. The extracts were analyzed for primary and secondary metabolites. The anticancer activity was tested using the MTT assay on HeLa cells, and anti-inflammatory activity was assessed using a luminol-enhanced chemiluminescence method. Data analysis was conducted using IBM SPSS Statistics Version 25, focusing on inferential statistics to compare the bioactivity of the extracts against standard drugs.
Results: Phytochemical analysis confirmed the presence of proteins, lipids, carbohydrates, alkaloids, flavonoids, and tannins. The dichloromethane extract showed significant anti-inflammatory activity with 58.6% inhibition at a concentration of 50 µg/ml and an IC50 of 8.966±1.03. The methanol extract exhibited minimal anticancer activity with an 8.3% inhibition rate at 30 µg/ml, suggesting low efficacy against HeLa cells compared to the standard drug, Doxorubicin, which showed a 101.2% inhibition.
Conclusion: The study confirms that Ficus benjamina L. contains bioactive compounds with potential anti-inflammatory benefits and limited anticancer activity. These findings support the traditional use of the plant in treating inflammatory conditions and highlight the need for further research to optimize extraction techniques and expand biological testing.
Research on the Development Status and Optimization Strategies of Poetry Immersion Experience
Authors: Chen Ruiying , Li Hanchi , Xu Ruiqing , Li Hantong , Wang Xiaohua
Published: April 2024

In the strategic layout of "creative transformation and innovative development of excellent tradi-tional culture" at the cultural level, the Chinese Poetry Conference broadcast on CCTV, and the 2024 Spring Festival Gala Poetry Chang'an, all of which can be seen that Chinese poetry has shown a vigorous development trend, and the intermingling of poetry dissemination and science and tech-nology has become increasingly close, and the "The Longest Day In Chang'an Theme Block" located in Xi'an is even more typical. The "The Longest Day In Chang'an Theme Block" in Xi'an is more typical. This paper researches the development status of a poetry immersion experience and proposes optimization strategies through field research, questionnaire survey, and SPSS analysis, and then combines the theory of five senses marketing and industrial integration.
Optimizing the location choice of reverse logistics recycling network for end-of-life photovoltaic modules based on the EPR principle
Authors: Zhang Xinyu
Published: April 2024

With the rapid development of the photovoltaic (PV) industry, the collection and recycling of end-of-life PV modules is facing a new challenge. Based on the EPR principle (Extended Producer Responsibility principle), this paper investigates the location choice of reverse logistics recycling network for end-of-life PV modules from the perspective of different stakeholders. In this study, a mixed integer programming (MILP) model is established to optimize the reverse logistics network of end-of-life PV modules with the objective of minimizing the total cost of the reverse logistics network, taking into account a four-tier recycling network system with customers going to the recycling centre, dismantling and processing centre, remanufacturing centre and waste disposal agency, and three recycling solutions are designed according to the EPR principle, and the optimal solution is found with the help of CPLEX software. Optimal solution, so as to determine the siting of facilities in the network and the distribution among each node. We take Zhejiang Province, one of the leading regions in China for promoting distributed PV applications, as the research object, and plan and design the recycling network of end-of-life PV modules in Zhejiang Province, determine the siting of the network as well as the distribution of the traffic to validate the validity of the MILP model, and provide opinions and references for the recycling problem of end-of-life modules in the future.
Motivations for Socially Responsible Investing: The Impact of Attitudes, Subjective Norms, and Financial expectations
Authors: Zhang Xiaojia
Published: April 2024

This study looks forward to exploring and understanding what the reasons for the desire of retail investors in might be making Socially Responsible Investments (SRI) in the Chinese stock market and to get an estimate of how valid the theory of reasoned action (TRA) could be. This is intended to look at how such factors as attitude, subjective norms, financial expectations, and risk propensity influence investors to engage in SRI in China. This research builds on previous studies that introduced financial expectations as a crucial new construct, enhancing the depth and rigor of TRA model in examining investment intentions. This assumption posits that investors comprehensively consider the investment situation, weighing not only its societal impact but also its financial returns, and only after considering these outcomes comprehensively will they make decisions on SRI. Risk propensity has been used as moderator in this research model relationship. Whether risk propensity influences the association between attitude, subjective norms, and financial expectations with investment intentions has been test in this study. The study results show risk propensity plays a significantly moderate role in relations of attitude, subjective norms, and financial expectation to intentions with the analysis indicating a positive effect. Its results will be able to provide more reference for the SRI studies and a new angle for capital market researchers, market information providers, and investors.
Research on Green Logistics Development in Chengdu-Chongqing Region under the Perspective of Game Theory
Authors: Geng Qi , Zhao Wanru
Published: April 2024

Chengdu-Chongqing Twin Cities Economic Circle is an important growth pole for the formation of high-quality development in western China and has a unique and important strategic position in the overall situation of national development. Chengdu-Chongqing two places not only vigorously promote the construction of logistics corridors and infrastructure connectivity, but also promote the logistics of all kinds of factors of production, including reasonable flow and efficient agglomeration, and strive to promote the Chengdu-Chongqing two places to the green logistics, cost reduction and efficiency to make effective exploration. The paper first analyzes the current situation and problems of green logistics construction in the Chengdu-Chongqing area, and then establishes an evolutionary game model between the government, enterprises, and consumers based on the game theory perspective, to try to put forward reasonable suggestions for the development and construction of green logistics in Chengdu-Chongqing area.
A Study on Marketing Strategies of Catering Enterprises from a Customer centric Perspective-- Taking Ningbo Wurong Famous Kitchen Catering Co., Ltd. as an Example
Authors: Sun Hezhen
Published: April 2024

With the increasingly fierce market competition and the diversification of consumer demand, enterprises no longer only focus on the product itself, but also need to put customer needs and satisfaction at the core position, and build a customer-oriented marketing strategy. This article explores the problems in the customer-oriented marketing strategy of Ningbo Wurong Famous Kitchen and Catering Co., Ltd., and proposes targeted measures to optimize marketing strategies, providing reference and inspiration for other catering industries, promoting the entire industry to move towards a customer-oriented marketing concept, improving consumer satisfaction, and promoting sustainable development of the enterprise.
A Study on the Experience of Hydrogen Energy Research and Development in Suzhou City
Authors: Cheng Xiaorong
Published: April 2024

Through the exploration of advanced models of the hydrogen energy industry both domestically and internationally, it has been found that many developed countries abroad attach great importance to the hydrogen energy industry and provide policies that greatly help the development of the hydrogen energy industry. Whether it is funding, talent, or related supporting laws, they are relatively complete to help enterprises develop hydrogen energy. Beijing, Zhangjiakou, Foshan, and Yunfu cities in China have advanced experience in the construction of hydrogen energy industrial parks. Their park construction not only conforms to local characteristics, but also brings different changes to their surrounding areas, providing favorable assistance for the development and expansion of hydrogen energy.
Influence of fan loyalty on fans' behavior of purchasing products endorsed by idolized idol' brands
Authors: Liao Tianyue
Published: April 2024

Celebrity endorsement is a commonly used marketing method, since the 1980s, most companies have chosen celebrity endorsement, celebrity endorsement in today's era of the full outbreak of celebrity endorsement can be seen everywhere by different brands. Not only that, along with the Internet access to the entertainment industry, the development of fan culture, but also because of the development of fan culture, followed by the generation of "fan economy",: fan economy "in today's market is a force that cannot be ignored. The loyalty of the fans to the celebrities included in the fan economy is an important criterion for the development of the fan economy. This paper only takes star loyalty as the research objective to study its influence on fans' behavior of purchasing products endorsed by idol brands. This paper uses a questionnaire to conduct a survey, and the respondents are all fans of the Korean idol group NCT. Behavioral loyalty and attitudinal loyalty are studied, and finally, it is concluded that fan loyalty has an impact but not a correlation on fans' behavior of purchasing idol brand endorsement products.
A study of the institutional structure of China's overseas establishment of private military companies
Authors: Chen Sining
Published: April 2024

Private military companies provide specialized military knowledge, skills and military services of all kinds to the State sector and its governmental agencies (including the military forces to which they belong), international organizations, commercial enterprises and so on. With the development of economic globalization and changes in the international situation, their role in the international arena is becoming increasingly important. For this reason, the gradual development of China's system for the establishment of overseas private military companies on the basis of the experience gained from the establishment of private military companies in other extra-territorial countries deserves greater attention and recognition.
Analysis of the Influencing Factors of Inventory Management of listed Companies in Shandong Province
Authors: Liu Zichun
Published: April 2024

This paper studies the inventory management of 25 listed companies in Shandong Province, and uses the current ratio, return on equity, inventory turnover and other indicators to analyze the inventory management of different industrial companies and the main influencing factors. Throug h descriptive analysis, correlation analysis, factor analysis and other methods, a linear regression model is constructed to determine the relationship between inventory management and its influencing factors, and suggestions and countermeasures are put forward to provide reference for the improvement of inventory management of listed companies in Shandong P rovince and the balanced long-term development of the industry.
Research on Communication Simulation of PROFIBUS Multi-master System
Authors: Sun Hongxiao , Zhe Qiang , Rao Ziyi , Liu Yuliang , Liang Geng
Published: April 2024

As the application background of fieldbus becomes more and more extensive, PROF I BUS contains multiple master stations, and a multi-master system with multiple slave stations emerges at the historic moment. This paper establishes a multi-master communication system model and uses simulation technology to study the relationship between the target token cycle time, token waiting time, and master site address value.
Wireless Charging Technology Improvement for New Energy Vehicles
Authors: Su Ruilin
Published: April 2024

In the operation of new energy vehicles, the energy supply method is directly related to the range and stability of the vehicle, and wireless charging technology is becoming a hot spot in the industry because of its efficient and convenient characteristics. This paper will discuss the core technology of wireless charging in new energy vehicles, covering the related equipment construction, compensation network design, and the design of key components of wireless charging technology improvement in new energy vehicles. The article will analyse the detailed results of the actual operation of the system, aiming to provide theoretical support and practical guidance for the application of wireless charging technology in new energy vehicles, and at the same time promote the further development of the new energy vehicle industry.
Analysis and Optimization Design of U-Shaped Ironless Permanent Magnet Linear Synchronous Motor
Authors: Zhang Longqi , Zhao Lei , Li Shihao
Published: April 2024

The working speed of the U-shaped ironless permanent magnet linear synchronous motor is determined by the frequency and pole pitch. When the motor’s working speed is required to be constant, different combinations of frequency and pole pitch can be chosen. This article mainly discusses the influence of the pole pitch on the motor performance when other parameters are kept constant. First, the magnetic field of the motor permanent magnet is analyzed using the equivalent magnetizing current method to discuss the relationship between the pole pitch and the motor air gap magnetic field. Then, the finite element method is used to analyze the influence of the pole pitch on the motor air gap magnetic field, transverse edge effect, and electromagnetic thrust considering the saturation effect of the magnetic yoke. The research shows that under the conditions of constant motor basic structural parameters and speed, and the same amount of permanent magnet material, both the air gap magnetic density and the motor thrust line density have maximum values as the pole pitch changes. The research results have certain guiding significance for the design of this type of motor.