bluuebunny/crossref_metadata_2025 huggingface dataset:
Recurrent Glioblastoma Multiforme
Authors: Bestari Reno , Indra Syarif
Published: March 2020

Glioblastoma multiforme (GBM) merupakan jenis tumor ganas terbanyak pada otak dengan tingkat rekurensi tinggi mencapai 90%. Penyebab pasti belum diketahui, namun insiden meningkat dengan adanya riwayat glioma dalam keluarga. Diagnosis pasti ditegakkan dengan pemeriksaan histopatologi sel tumor yang ditandai dengan adanya aktivitas mitosis yang tinggi, proliferasi mikrovaskular dan nekrosis. Penatalaksanaan Glioblastoma multiforme melibatkan multidisiplin ilmu, yaitu neuroonkologi, neuropatologi, bedah saraf dan radiasi-onkologi. Penatalaksanaan pasien recurrent GBM yang unresectable adalah dengan kemoterapi sistemik (Temozolomid), radioterapi ulang atau bisa hanya dengan terapi paliatif. Dari beberapa penelitian didapatkan apabila pasien mendapat terapi yang agresif, maka diperkirakan dapat bertahan 14-24 bulan, namun apabila pasien tidak mendapat terapi, maka kemungkinan hanya bertahan selama 4 bulan karena memang prognosis tumor glioma ini sangat buruk.
DYKE DAVIDOFF MASSON SYNDROME (DDMS)-A rare case
Authors: Faiza Yaumi , Indra Syarif
Published: March 2020

AbstrakDyke Davidoff Mason Syndrome (DDMS) merupakan suatu kasus jarang yang memperlihatkan adanya atrofi pada satu hemisfer serebral (hemiatrofi). Sindrom ini terjadi karena gangguan perkembangan otak pada periode fetal atau periode awal kehidupan. Gejala klinis bervariasi pada setiap individu, dipengaruhi oleh seberapa luas kerusakan otak yang terlibat. Gejala klinis yang paling sering terjadi adalah kejang berulang, wajah asimetris, hemiparese kontralateral, retardasi mental, gangguan belajar, gangguan bicara dan bahasa. Gangguan sensorik dan gejala psikiatri seperti skizofrenia dapat terjadi, namun jarang dilaporkan. Gambaran radiologi berupa hemiatrofi serebral. Dilaporkan seorang laki-laki berumur 17 tahun dating dengan status epileptikus, hemiparese sinistra, parese nervus VII dan XII sinistra tipe sentral, gangguan tumbuh kembang, dan gangguan belajar. Pada pemeriksaan MRI otak ditemukan gambaran hemiatrofi serebri dekstra dan gliosis serta porencephalic cyst besar di kanan posterior yang mendukung kearah diagnosis Dyke Davidoff Mason Syndrome (DDMS).
Capacidades y recursos que influyen en las empresas femeninas
Authors: Escandón Barbosa Diana , Arias Sandoval Alberto
Published: March 2020

Este artículo tiene como propósito tratar de conocer las principales capacidades y los recursos que influyen en las empresas femeninas. Para lo cual se analizan los datos recopilados por GEM Colombia 2009, pero filtrando la base de datos y permitiendo utilizar solo lo relacionado con el género femenino. Dentro de los resultados se logró obtener un modelo consistente con la literatura sobre competitividad, destacando los recursos humanos, la innovación y la internacionalización. Sin embargo, no hay evidencia que explique cada una de estas variables por género y mucho menos la relación con competitividad. Para lo cual, los autores plantean una primera aproximación y que puede generar tendencias investigativas al respecto. La metodología aplicada en este articulo, es un sistema de ecuaciones estructurales, mediante el paquete estadístico SPSS Amos 18, que permite generar un esquema de relaciones entre las variables, y, acercarse a las tendencias de modelos en las explicaciones de las ciencias sociales.
Consecuencias del aprendizaje organizativo en las relaciones comerciales entre empresas
Authors: López Sánchez José , Santos Vijande María Leticia , Trespalacios Gutiérrez Juan
Published: March 2020

El objetivo principal de este estudio es analizar la influencia del aprendizaje organizativo (AO) sobre la satisfacción y la lealtad en las relaciones comerciales entre empresas. Para ello se plantea un marco teórico donde se adopta como unidad de análisis la relación diádica que mantienen las empresas fabricantes con su principal distribuidor. En el análisis de los datos se emplean sistemas de ecuaciones estructurales con una muestra de empresas españolas. Los resultados empíricos obtenidos aportan evidencias acerca de que el AO del fabricante es un antecedente de los resultados alcanzados en los intercambios relacionales. Así, el mayor grado de AO de la empresa fabricante incide de modo directo en el grado de satisfacción del distribuidor principal y también actúa de modo indirecto sobre su grado de lealtad. Se corrobora además que dicho AO potencia de un modo directo los resultados empresariales del fabricante. Las limitaciones del estudio son las típicas asociadas al uso de la investigación basada en encuesta. Por último, la varianza del método común no fue un problema en este estudio.
Modelo de gerencia del conocimiento: visión integral
Authors: Bernal Torres César A
Published: March 2020

Este artículo tiene como propósito el diseño de un modelo integral de la gerencia o administración del conocimiento como recurso estratégico para potenciar la capacidad competitiva de las organizaciones. El objetivo del modelo es contribuir a dar respuesta a dos inquietudes básicas de muchos directivos empresariales y estudiosos del tema en el entorno de los países en desarrollo: a) la necesidad de modelos gerenciales propios y pertinentes a la realidad de las organizaciones y b) la integración de la diversidad de modelos dispersos existentes sobre este campo para facilitar su comprensión y aplicación. La construcción del modelo se realizó a partir de una amplia revisión bibliográfica sobre el tema, un trabajo de campo en el contexto de referencia con entrevistas a directivos empresariales y un análisis de expertos.
Geografía económica y flujos de inversión extranjera en América Latina
Authors: Vanegas Lopez Juan Gabriel , Restrepo Morales Jorge Aníbal , Muñeton Santa Guberney
Published: March 2020

El artículo analiza los determinantes de los flujos bilaterales de inversión extranjera directa (IED) en algunos países de América Latina y, con base en la metodología de estimación de un modelo gravitacional de inversión, se incorporaron elementos que han sido abordados desde la Nueva Geografía Económica. Se comparó y controló el peso de los factores que están directamente relacionados con la IED; se agregaron al análisis variables que dan cuenta de: (i) inversión potencial, como tamaño del mercado y tamaño comercial de los países y sus socios de inversión; (ii) factores que históricamente han estado arraigados y predeterminados a los países: la distancia geográfica, la existencia de fronteras, el idioma común; y (iii) factores institucionales y gubernamentales, generados mediante variables categóricas que explican las restricciones e incentivos a la inversión como la participación en acuerdos comerciales y de inversión, y el otorgamiento de accesos preferenciales. El principal hallazgo determina que la distancia y las variables de inversión potencial juegan un papel determinante en la configuración de los patrones de inversión en algunos países de la región.
Formación y desarrollo de competencias gerenciales para los gestores hoteleros
Authors: Castro Milano Luis Arcadio
Published: March 2020

El talento humano es la piedra angular para propiciar desde las “nuevas lógicas” empresariales respuestas a las necesidades de cambios en el comportamiento de la relación binomial oferta-demanda en los hoteles dedicados a la gestión y producción de servicios puros basados en las personas. Por esta razón se necesitan gestores concienzudos, éticos, motivados, capacitados y comprometidos con la satisfacción de los clientes internos y externos. El presente artículo de investigación científica y tecnológica, fundamentado en el eje temático gestión del talento humano y liderazgo, profundiza en la formación y el desarrollo de las competencias gerenciales del talento humano en puestos de trabajo de gestores, en los establecimientos hoteleros inscritos en el Registro Turístico Nacional (RTN) y categorizados como hoteles cinco estrellas. El discurso está fundamentado en una investigación aplicada de campo y transeccional, realizada en Venezuela, en el estado Nueva Esparta, específicamente en la Isla de Margarita. La disertación concluye demostrando la necesidad de emprender de forma inmediata la formación y el desarrollo de las competencias gerenciales en los establecimientos de alojamiento turístico. Se recomienda aprovechar los incentivos tributarios establecidos en la legislación venezolana para financiar las actividades de formación y desarrollo de las competencias gerenciales.
Impacto de la orientación al aprendizaje en la innovación de las MIPYMES colombianas
Authors: Contreras Palacios Fred D. , Gálvez Albarracín Edgar J. , González-Campo Carlos H.
Published: March 2020

Múltiples estudios demuestran que a nivel mundial, la innovación es fuente de ventaja competitiva y que por ello es importante conocer los factores que la estimulan. Es por esto que la investigación que aquí se presenta tiene por objetivo analizar el efecto que tiene la orientación al aprendizaje organizacional sobre la innovación de las empresas. Se realizó un estudio empírico con 403 MIPYMES colombianas. Los resultados obtenidos a través de regresiones lineales múltiples, muestran un efecto altamente positivo en la relación estudiada, lo que tiene importantes implicaciones para empresarios, la academia y el sector gubernamental, porque les indica que un estilo gerencial que estimulen la organización práctica como la divergencia, la generación de ideas novedosas, la toma de riesgos, el intercambio de conocimientos, los acuerdos de cooperación con universidades y otras empresas, la apertura, la experimentación y el cambio continuo, generan un mucho mejor desempeño innovador.
Editorial v29n49
Authors: Ceballos Molano Raquel
Published: March 2020

Con la publicación de este número, culmino mi período como Editora de la revista Cuadernos de Administración, noble ejercicio que he desempeñado a partir de la edición N° 46 de diciembre de 2011 y es la oportunidad para agradecer a todos los autores por sus aportes, a los árbitros por la seriedad de sus evaluaciones, a todo el equipo editorial y las directivas de nuestra Facultad por el apoyo recibido para mantener el posicionamiento como revista indexada A2 del Índice de Publicaciones Seriadas, Científicas y Tecnológicas Colombianas IBN Publindex, que permite su divulgación por las principales bases de datos internacionales, la última de ellas, la base de datos Fuente Académica Premier - EBSCO.
Un caso práctico para el análisis del neuromarketing visual en el Centro Comercial Ventura Plaza (Cúcuta, Colombia)
Authors: Avendaño Castro William Rodrigo
Published: March 2020

Los avances en las áreas de la psicología, la neurociencia, el ámbito cognitivo y la comprensión sobre el funcionamiento del cerebro humano han posibilitado que otras disciplinas y áreas del conocimiento formulen nuevas teorías. Este es el caso del marketing, que haciendo uso de los últimos descubrimientos a nivel cerebral, ha incorporado estrategias para la captación de clientes. Se hace una revisión de las prácticas visuales de neuromarketing de 124 establecimientos del Centro Comercial Ventura Plaza, el más importante de la ciudad de Cúcuta (Norte de Santander, Colombia). La muestra estuvo representada por 71 establecimientos de textiles, 25 de comidas, 12 de electrodomésticos, 11 de diversión y entretenimiento y 5 de libros. Se aplicó una matriz que recopiló la información sobre la imagen externa e interna de los establecimientos atendiendo al uso del color, la luz y la imagen fotográfica. Los resultados muestran que un buen porcentaje de los establecimientos aplican los principios del neuromarketing asociados con la percepción sobre el color, la luz y la imagen fotográfica.
Software para mejorar la aplicación de técnicas cuantitativas en estudios prospectivos
Authors: Cabarcas Alvarez Amaury , Martelo Gomez Raul Jose , Tovar Garrido Luis Carlos
Published: March 2020

Durante las dos últimas décadas se ha observado preocupación de organizaciones para lograr competitividad y obtener estabilidad en el mercado, impulsándolas a analizar ventajas de ir a un futuro deseado, haciendo uso de herramientas como los estudios prospectivos. Con el fin de optimizar la aplicación de estudios prospectivos, se han desarrollado herramientas de apoyo que aún no abarcan ciertos intereses de los involucrados como el uso de recursos económicos, ambientales, tecnológicos y humanos. Para suplir la necesidad encontrada, se planteó un software que contribuya al acompañamiento de estudios prospectivos apoyándose de tecnologías Web 2.0 independientemente de técnicas utilizadas por la persona guía del mismo, para lograr racionalizar recursos aprovechando las ventajas que ofrece la web. La investigación permitió concluir que los estudios prospectivos constituyen una alternativa viable para las organizaciones que desean planificar para alcanzar sus objetivos empresariales. Sin embargo, el intento de lograr el futuro deseable traería una serie de costos, que se incrementarán cuando la aplicación de estos estudios se lleve a cabo al margen de las herramientas, software y modelos adecuados. Por esta razón, el hombre debe emplear herramientas tecnológicas que combinen métodos, software, capacidad colaborativa y de integración como la ofrecida por la Web 2.0 para optimizar sus procesos y permitir así, que áreas como la prospectiva, alcancen un alto nivel de eficiencia y masificación
Constructos teóricos para abordar, de un modo investigativo, problemas entre marketing, producción y logística en las empresas colombianas
Authors: Varon Sandoval Alexander
Published: March 2020

Este artículo propone un modelo de constructo teórico, a partir de una investigación cualitativa, por medio de cuestionario con preguntas abiertas y una revisión teórica. La población objeto de estudio estuvo representada por los colaboradores de los departamentos de marketing, producción y logística, de algunas empresas de manufactura en Colombia indistintamente seleccionados, entre los años 2006 y 2007. El objetivo fue generar constructos teóricos que sirvieran de base para la investigación de los conflictos entre marketing, producción y logística, dentro de las empresas colombianas, justificado en la presencia del conflicto, en ese momento poco estudiado, entre estas áreas de la organización. En la metodología, se establecieron varias etapas, entre ellas: a) la recopilación de información pertinente, b) encuestas a personas que habían trabajado o estuvieran trabajando en alguna de las áreas de interés, c) determinación de un marco teórico y conceptual, a partir de la revisión de autores especializados en este tema.
Capabilities of mathematical modeling of network interaction of the law enforcement authorities
Authors: Mironov Rinat
Published: March 2020

The subject of this research is the mechanism of integrated cooperation of law enforcement authorities, which due to application of modern technologies and capabilities of mathematical modeling and with consideration of the current political, organizational and normative-legal factors of counteracting criminality, would allow eliminating the organizational and management contradictions between the virtually established vertical-subordination model of interaction of the law enforcement authorities and the framework of public administration. The goal of this work consists in introduction of the basic foundations of mathematical modeling of interaction of law enforcement authorities at the intersection of two scientific directions – game theory and social network analysis, in the process of improving social technologies of public administration in the law enforcement sphere. The article is prepared on the basis of law enforcement practice leaning on the positions of social administrative theory, cybernetics, information analysis, and most recent achievements in the area of cross-disciplinary studies. The scientific novelty is defined by the hypothesis on the network social structure. Due to this fact, the developed mechanism of network interaction of law enforcements authorities [4, p. 31-41] is an element of digital economy responsible for solution of economic-mathematical problems, which in turn, substantiates the mechanism of improvement of social technologies of public administration in the law enforcement sphere.
ПІДВИЩЕННЯ ЕФЕКТИВНОСТІ УПРАВЛІННЯ ПРОМИСЛОВИМИ ПІДПРИЄМСТВАМИ НА ОСНОВІ РЕАЛІЗАЦІЇ PLM-МОДУЛЯ
Authors: Lysak Viktor
Published: March 2020

У статті розглянуто напрями підвищення ефективності управління промисловими підприємствами в контексті сучасних економічних викликів, за умов поглиблення глобалізаційних процесів та зростання конкуренції. Окреслено особливості реалізації концепції управління життєвим циклом продукту, розроблено структурну схему функціонування PLM-модуля автоматизованої системи управління підприємством та проаналізовано вартісні характеристики його складових серед поширених програмних продуктів на вітчизняних підприємствах. Проаналізовано динаміку окремих техніко-економічних показників після реалізації PLM-модуля та запропоновано основні напрями підвищення ефективності управління підприємством у контексті використання сучасних економічних підходів та науково-технічних розробок.
O ensino de implantodontia nas graduações brasileiras de odontologia: um estudo transversal
Authors: Faria Luan Viana , De Oliveira Gisele Aparecida , Grázzia Maria Eduarda Povoleri , Medeiros Yuri de Lima , Lopes Danielle Fernandes , Leite Isabel Cristina Gonçalves
Published: March 2020

Objetivo: Fornecer uma visão geral da atual oferta da disciplina de implantodontia nos cursos de Odontologia das Instituições de Ensino Superior (IES) brasileiras, incluindo as características curriculares da disciplina.  Métodos: Foram analisadas as grades curriculares disponibilizadas em ferramentas online, como os sítios web oficial ou os e-mails de coordenadores de cursos de todas as IES de odontologia dos estados sul e sudeste do Brasil, cadastradas no portal e-MEC do Ministério da Educação.  Resultados: 36 (16,51%) eram escolas públicas e 182 (83,48%) privadas, sendo que IES públicas oferecem mais a disciplina que IES privadas (86,1% contra 54,9%, p<0,001). Quando administrado, o conteúdo de implantodontia se dá de forma teórica em mais de 60% dos casos (p=0,723), independente da natureza do curso. Tanto nas públicas quanto nas privadas, a disciplina é mais frequentemente ofertada como obrigatória, 67,7% e 92,3% respectivamente, embora com frequências estatisticamente diferentes (<0,001). A carga horária média é de 60,97h, nas públicas é de 53,29h (DP=23,943) e nas privadas de 63,99h (DP=34,627). Conclusão: Grande parte das IES da região sul e sudeste do Brasil, especialmente as instituições particulares, ainda não ofertam a disciplina de implantodontia. Quando ofertada, a disciplina tende a ser obrigatória e teórica.
Síndrome do Overlap: Esclerose sistêmica sem esclerodermia associado à polimiosite: Relato de Caso
Authors: Pontes Carla Daniele Nascimento , Da Silva Yuri Jose Almeida , Maneschy Rodrigo Bona , De Holanda Lucianna Serfaty , Carvalho Carolina Tavares , Dos Santos Júnior Jose Deorilo Cruz Gouveia , Campos Valeria da Silva , Araújo Mariana Diniz , De Moraes Karen Larissa Lucena , De Lima Pamela de Fátima Cunha Mendes
Published: March 2020

Objetivo: O presente estudo teve como objetivo descrever a associação simultânea de duas doenças do tecido conjuntivo, de natureza auto-imune, sendo compostas pela esclerose sistêmica (ES) e polimiosite (PM). Demonstrando a raridade da sobreposição e importância de inclui- lá como hipótese diagnostica desses pacientes reumatológicos. Detalhamento do caso: Paciente do sexo masculino, 39 anos, com diagnóstico prévio de fibrose pulmonar idiopática, com presença de dispneia aos esforços, fenômeno de Raynaud, artralgia e fraqueza muscular proximal. Sendo encontrada a presença de marcadores reumatológicos e enzimas musculares positivos. Como o fator antinuclear (FAN) 1/320 padrão: misto do tipo nuclear pontilhado e nucleolar, ANTI-SCL 70 ≥ 240 e elevação na aldolase/creatina fosfoquinase. Considerações finais: Destaca-se a necessidade de novos estudos epidemiológicos e a realização de protocolos específicos para uma melhor abordagem diagnóstica e terapêutica desses tipos de casos, pois a relação da esclerose sistêmica e polimiosite, representa uma das síndromes de sobreposição mais incomuns na literatura.
Percepção da assistência prestada pela equipe multiprofissional da sala vermelha de um hospital de urgência e emergência do interior de Rondônia
Authors: Oliveira Angelica Inacio da Cruz , Lima Angela Antunes de Morais , Sousa Emanoela Maria Rodrigues de , Gouvêa Poliana Deyse Pereira , Rosa Cassia de Oliveira Pinto , Maestá Tatiane
Published: March 2020

Objetivo: Analisar a assistência prestada no setor de urgência e emergência (sala de estabilização), através do perfil da equipe multiprofissional. Métodos: pesquisa de características qualitativas, realizada em agosto de 2019 em uma instituição hospitalar de urgência e emergência. Para análise dos dados foi utilizado o programa Microsoft Office Excel® versão 2010. Resultados: Os profissionais participantes da pesquisa foram compostos em sua maioria 56% pelo gênero masculino. 76% dos entrevistados possuem nível superior, destes apenas 12% possuem pós- graduação ou especialização em urgência e emergência. 54% dos participantes não realizam cursos de aprimoramento na área de urgência e emergência, e 52% nunca realizaram cursos como Suporte Avançado de Vida no Trauma (ATLS), Suporte Avançado de Vida Cardiovascular (ACLS) e atendimento pré-hospitalar (APH). 68% responderam que a unidade onde trabalham não oferece cursos de atualização em urgência e emergência e 84% não participam de tais programas. 84% da equipe entrevistada se sentem aptos a atuar no setor de urgência e emergência mesmo sem qualificação adequada. Conclusão: Diante dos resultados encontrados na atual pesquisa se faz necessário o complexo hospitalar incentivar e investir em capacitações e treinamentos dos profissionais atuantes no pronto socorro visando qualificar a equipe para melhorar o serviço prestado.
Investigating Multicomponent Approaches for the Site-Selective Conjugation of Native Proteins
Authors: Sornay Charlotte , Hessmann Steve , Erb Stéphane , Dovgan Igor , Ehkirch Anthony , Botzanowski Thomas , Cianferani Sarah , Wagner Alain , Chaubet Guilhem
Published: March 2020

Site-selective modification of proteins has been the object of intense studies over the past decades, especially in the therapeutic field. Prominent results have been obtained with recombinant proteins, for which site-specific conjugation is made possible by the incorporation of particular amino acid residues or peptide sequences. While mutant proteins take most of the spotlight, native and natural proteins have been left in the shadow and site-selective methods to conjugate these are underexplored. In addition, while these few methods give good results on small to medium-sized proteins, most of them tend to fall short whenever applied to bigger constructs such as antibodies. To address this limitation, we reasoned that aiming at the simultaneous conjugation of two amino acid residues should give higher chances of developing a site-selective strategy compared to the large majority of existing methods that solely target a single residue. We opted for the Ugi four-center three-component reaction to implement this idea, with the aim of conjugating the side-chain amine and carboxylate groups of two neighbouring lysine and aspartate/glutamate. Herein, we show that this strategy can give access to valuable conjugates bearing several different payloads, and limits the potential conjugation sites to only six on the model antibody trastuzumab.
Estimation of Effective Parameters for the Transition-Metal Complexes by Mapping Self-Interaction Correction onto GGA+U
Authors: Parq Jae-Hyeon
Published: March 2020

We propose a method to calculate the Hubbard U parameter in GGA+U or the α parameter in the atomic self-interaction correction (ASIC) scheme for transition-metald orbitals by mapping the self-interaction correction (SIC) onto GGA+U, which issuitable for atom-centered basis sets. SIC can oﬀer a substitute for the HubbardU parameter in GGA+U, although its usage should be limited considering the differences between GGA+U and SIC. Approximations to reduce computational costfor self-interaction (SI) corrected localized orbitals are deduced from the propertiesof the unitary transformation in SIC and the atomic likeness of molecular orbitalsdominated by transition-metal d orbitals, and the parameters are obtained from theapproximate forms of the localized orbitals. First-row transition-metal complexeswere tested, and the results are comparable to experimental measurements and previous calculations. Our method does not guarantee better results than those ofthe linear response method or hybrid functionals, but mapping from SIC suppressesoverestimation of the U parameter to obtain proper geometries and energies for Feporphyrin-imidazole, Fe-porphyrin-CO and FeO2 modeling
Evidence for Photocatalyst Involvement in Oxidative Additions of Nickel-Catalyzed Carboxylate O-Arylations
Authors: Malik Jamal , Madani Amiera , Pieber Bartholomäus , Seeberger Peter H.
Published: March 2020

In this study we use in situ infrared tracking to describe the kinetics of dual photo- and nickel-catalyzed carboxylate O-arylations. We examined both a state-of-the-art homogeneous (Ir(ppy)3) and heterogeneous (graphitic carbon nitride) photocatalyst, comparing their kinetics to each other, and to the existing mechanistic proposal. We argue against the current hypothesis, specifically that the photocatalyst is only involved to trigger a rate-limiting reductive elimination.
High Serum Osmolality May Predict the Disease Severity in Patients with Acute Ulcerative Colitis
Authors: VURAL Abdussamed , VURAL Aslı , VURAL Selahattin , TURFAN Selim , DÜLGER Ahmet Cumhur
Published: March 2020

Objective: Ulcerative colitis (UC) is characterised by chronic immun- mediated inflammation of the colonic mucosa. The Truelove and Witts (TW) criteria have been used to define the severity of the UC. Otherhand, a simplier and unified laboratory tool is needed for better definition of high risk patients with UC. The aim of the study, especially in emergency service applications, was to determine the usefulness of serum osmalality as a biomarker which can easily and rapidly predict the severity of the disease, in which the patient will be advised to be hospitalized after the symptomatic treatment. Materials and Methods: In this single-center, retrospective cohort study, we collected data of 62 hospitalized patients with UC such as demographic characteristics and blood sample results evaluated by clinicians. Truelove and Witts (TW) scores of the patients along with serum osmolality were calculated. Stata 14.0. package program was used for data analysis. P <0.05 was considered statistically significant. Results: According to our results, patients with hyperosmolality were more likely to have severe UC as defined by having higher scores of TW criteria at baseline.Conclusion: As a conclusion, serum osmolality can be considered as an useful predictor to demonstrate the severity of the disease.
Karabük İli ve Çevresinde İdrar Kültürlerinden İzole Edilen Escherichia coli Suşlarının Antibiyotik Duyarlılıkları
Authors: KURU Cüneyt , KAL ÇAKMAKLIOĞULLARI Elçin
Published: March 2020

Amaç:Üriner sistem enfeksiyonları (ÜSE)
bakteriyel enfeksiyonlar arasında en yaygın olanıdır ve bu enfeksiyonlarda en
sık izole edilen etken Escherichia coli (E.coli)’dir. Biz bu çalışmada, idrar
kültüründe E.coli üreyen suşların antibiyotik duayarlılıklarını değerlendirerek
bölgemiz için uygun ampirik tedavi seçeneklerini saptamayı amaçladık. Materyal ve
Metot: Bu
çalışmada Nisan 2016 - Aralık 2017 tarihleri arasında çeşitli poliklinik ve
servislerden gön¬derilen 21488 idrar kültürü retrospektif olarak incelendi.
İdrar kültürlerinden izole edilen bakterilerin tanımlanması ve antibiyotik duyarlılık
testleri için Phoenix ™ (Becton Dickinson Diagnostics, ABD) otomatize sistem
kullanıldı. 1875 poliklinik ve 390 servis
hastasından toplam 2265 E.coli suşu izole edildi.  Bulgular: Poliklinik hastalarından izole edilen suşların amikasine
%99,2, imipeneme %98.4, nitrofurantoine %97,6, meropeneme %97,3, fosfomisine
%96,8 ve gentamisine %84,4; servis hastalarından izole edilenlerin ise
amikasine %99,1, imipeneme %96,6, fosfomisine %96,5, nitrofurantoine %95,7,
meropeneme %93,1 ve gentamisine %82,2 oranında duyarlı oldukları saptandı. Sonuç: Bölgesel antibiyotik direnç oranlarının izlenmesi ampirik
tedaviye yön vermek açısından gereklidir. Böylece hem hastanın tedavisi etkin
bir şekilde yapılacak hem de uygun olmayan ampirik tedaviden kaynaklanan zaman
ve maliyet kaybının önüne geçilmiş olacaktır. Çalışmamızda bulduğumuz sonuçlara
göre amikasin, gentamisin, imipenem, meropenem, nitrofurantoin ve fosfomisinin
bölgemizdeki üriner sistem enfeksiyonlarının ampirik tedavisinde öncelikle
tercih edilmesi gerektiği kanaatindeyiz.
Rural consumers’ attitude towards khadi products
Authors: Padmasani  , S Muruganandan , M Yazhini
Published: March 2020

In this study the consumers‟ attitude towards khadi products is reviewed through Fishbein‟s attitude model. The influence of personal characteristics and purchasepreference factors on the attitude as well as the association between attitude and consumer‟s satisfaction are examined. This study shows that, overall, the consumers have positive attitude towards khadi product and also that the consumers who have higher attitude get more satisfaction.
Micro finance – an anti poverty vaccine for rural india
Authors: K Nithya Kala , K Vidya Kala , S Poornima
Published: March 2020

Micro- finance interventions are well-recognized world over as an effective tool for poverty alleviation and improving soc ioeconomic status ofrural poor.In India too, micro- finance is making headway in its effort for reducing poverty and empowering rural women. The need of micro finance arises because the rural Indiarequires sources of finance for poverty alleviation, procurement of agricultural and farms Micro finance is a programme to support the poor rural people to pay its debt and maintain social and economic status in the villages. As we know that India is agriculturebased economy, micro finance may be a tool to empower the farmers and ruralpeoples to make agriculture profitable. This research paper is highlighting a picture rural India as a developing segment for micro finance institutions.
Featurematching by skpcawithunsupervisedalgorithmand maximum probability in speech recognition
Authors: M Pavithra , G Chinnasamy , Periasamy Azha
Published: March 2020

A Speech recognition system requires a combination of various techniques and algorithms, each of which performs a specific task for achieving the main goal of the system. Speech recognition performance can be enhanced by selecting the proper acoustic model. In this work, the feature extraction and matching is done by SKPCA with Unsupervised learning algorithm and maximum probability. SKPCA reduces the data maximization of the model. It represents a sparse solution for KPCA, because the original data can be reduced considering the weights, i.e., the weights show the vectors which most influence the maximization. Unsupervised learning algorithm is implemented to find the suitable representation of the labels and maximum probability is used to maximize thenormalized acoustic likelihood of the most likely state sequences of training data. The experimental results show the efficiency of SKPCA technique with the proposed approach and maximum probability produce the great performance in the speech recognition system.
A study on hr issues in retail outlets in coimbatore
Authors: M G Saravanaraj , S Arulsenthilkumar , N Punitha
Published: March 2020

Although retailing is a one of the very emerging fast growing sector in our country, Now massive retail stores has been functioning in the nook and corner of the all across the areas for fulfilling the customer needs under one roof Now, various well reputed organizations are very clear to setting up shop in India; they have a passion to be closer to the customer. At this time when the country‘s retail business is going through a transformation, there is a Compelling need for those involved in retailing and those who wish to be involved to understand this phenomenon systematically so that they can practice it perfectly.However one of the most problematic parts in the retail industry is that of acquiring, developing and etaining the personnel involved in the business of retail. This article has been undertaken to identify the pertinent HR issues faced in the retail sector, with a focus on retail outlets in Coimbatore. In this Study, afoundation to the aspect of retailing has been given, which includes Retailing in the global and Indian scenario, retail formats, etc. Then primary data has been collected with the help of a questionnaire, with the help of which the HR issues involved in retail have been identified. In the end suggestions and recommendations have been provided.
An empirical study on barriers of innovation in indian smes
Authors: S Poornima , K Nithya Kala
Published: March 2020

Small and Medium Enterprises (SMEs) have emerged as the drivers of growth in several developed and developing economies across the world. Innovation has become the vital factor for the growth of small and medium scale enterprises. Hence, Innovation has turned out to be nucleus issue of various studies all over the world. In today‘s competitive world, India is far behind in innovation. The slow growth of innovation across various manufacturing sectors in India is cited as root cause for business failures in turbulent business environment. This paper aims at highlighting the barriers faced by entrepreneurs in SMEs in India. This study further makes sector wise analysis and suggests policy measures to enhance the adoption of innovation in SMEs. This study would serve as a guide to theentrepreneurs to compete internationally.
On the volatility of sensex
Authors: C Nateson , D Suganya
Published: March 2020

The present study seeks to analyse Volatility of popular stock index SENSEX. The present study is based on the closing time series data of SENSEX covering the period from 3rd January 2000, to 30th June 2011. The year 2008 has recorded higher Volatility compared to the other years of the study. Volatility fell in the year 2009 from the high of 2008. The years after were comparatively calmer. In the year 2000, the Volatility was higher signifying enhance market activity. The overall daily Volatility for SENSEX was approximately 1.70 % while the annualized value was approximately 25%-26%. Events Reported around Daily Returns in Excess of +/-5%have also been identified.
Factors influencing the choice of organized retail outlets and the behavior of the consumers in coimbatore city
Authors: A ANURADHA , R PRABHU
Published: March 2020

Factors influencing the choice of organized retail outlets and the behavior of the consumers in Coimbatore city ‖ of Tamil Nadu reveals the factors which influence the consumers to change their preference towards organized retailing. The objective of the study is formulated to analyse the most prioritized attributes of organized formats which attracts the consumers towards organized retailers in Coimbatore City. The Stratified random sampling (Two stage sampling) was adapted in the study and the primary data is collected through survey. Percentage analysis, Weighted Average method and ANOVA are used tointerpret the findings. It is found that the customers prefer organized retailers to unorganized retailers because of the store attributes such as quality, Convenience, Variety, Consistency, Price, Hygiene etc offered by the former. Income of the customers had a major influence on their choice of organized retail outlet especially when it comes to the availability of different varieties of products and display of information in the store.
A study on liquidity performance of top performing indian manufacturing companies
Authors: S POORNIMA , M THEIVANAYAKI
Published: March 2020

The term liquidity probably brings to mind the relationship of current assets to current liabilities. However, the concept of liquidity should encompass much more than simply these two balance sheet accounts. This study is based on previous ten years Annual Reports of the top performing manufacturing companies in India. In this study, liquidity is taken to mean the short term liquidity which refers to the ability of the firms to pay off the current liabilities. This study relates to the management of short term assets and liabilities and finding the relationship between liquidity, profitability and leverage measures of a firm.Short term liquidity has been considered crucial to the very existence of an enterprise. This will further lead to financial distress and finally corporate can go bankrupt. The conflict arises because the maximization of firm’s returns could seriously threaten the liquidity and on the other hand, the pursuit of liquidity has a tendency to dilute returns. The result can determine the risk postulate to that future customer. Additionally, this result can be utilized as a yearly appraisal of financial situation in making decisions to invest in the corporate. The result can contribute in advance an indication of the financial situation to aid the investor’s selection of companies.
Willingness to pay for improved water supply in rural areas of tamilnadu: an econometric analysis using tobit model
Authors: K DHANASEKARAN , R GANESAN
Published: March 2020

Provision of high quality and sustainable drinking water services for all the citizens, particularly the rural poor, is critical to enhance the economic productivity of any nation. Supply of safe and quality drinking water to the rural community remains a significant issue in the governance in India. It has been estimated that to provide safe drinking water to all rural habitations in the country with minimum satisfactory level of service would require a further investment of about Rs.450 billion. In view of increasing constraints, it would be a difficult task for the Government alone to mobilize such huge investment single handedly. Therefore, aproductive and pro-active involvement of user community and other stakeholders in resource mobilization and community participation in the implementation as well as the operation and maintenance of the system has become imperative. To translate the above strategy into practice, it requires massive efforts to transform the prevailing mindset of the major partners – the users, community, local Government, Government agencies, NGO’s etc. When users are involved in operation and maintenance of the systems, they are likely to be willing to pay forit.
Women empowerment
Authors: LILY GLADYS
Published: March 2020

The problem of women‘s development, therefore calls for sincere and dedicated efforts from the whole society,planners, administrators, philanthropists, social and educational workers. All the governmental and non-governmental organizations and developmental agencies need to work towards the development of women.Development of women is directly and indirectly related to national development. The effective management and development of women such as abilities, skills and other potentialities are of paramount importance for the economic development of the country. According to World Bank Report, the development of women yields important inter-generational benefits and productivity gains in future. Raising better employment opportunities for women raises the status of the families and derives economic and social progress.
Reverse mortgage – a tool of protract the economic independence of senior citizen
Authors: V MANICKAVASAGAM , S SAHUL HAMEED
Published: March 2020

India, the seventh largest country in size, continues to occupy the second largest populated country after China. The aged population in India (i.e. over 60 years) that stood at 84.7 million (7.5 per cent) in 2005 is expected to rise to 141 million (10.2 per cent) by 2020 and thereafter reach 194 million (13 per cent) in 2030. Even though income levels are going up and poverty declining, it can be reasonably expected that a significant number among the aged population would be in the lowincome category. The aged population requires additional attention both from the society and from the Government. More funds need to be allocated for pension, health and other social benefits of the aged people, while declining savings of the aged population could pose a threat in meeting such additional expenditure.
Kaizen for standardizing educational institutions
Authors: M Nagaraja , K Sivakumar , R Sundaresan , S Narayanan
Published: March 2020

Teaching, scientific and technological innovations are the most important key factors and heartof an educational institute. It is necessary to monitor and focus the entire aspects of an institute to bringoverall improvements. Effective teaching –learning process, quality, resource management and otherimprovement can be achieved in a short period of time using Kaizen. This is a Total Employee Involvement(TEI) technique which brings together all the employees of an organization right from top management toworkers for bringing continuous improvement in an academic organization.
Living Arrangements of Widowed Elderly Women and their Differentials: A Study in an Urban Setting of Tamil Nadu, India
Authors: Singh Neelu
Published: March 2020

Living arrangements in the twilight of life is a matter of primary concern for elderly widowed women. In view of this, an attempt is made to examine the effect of background characteristics on the living arrangements of the widowed elderly women making use of the data collected from 330 elderly widowed women from Coimbatore city, Tamil Nadu with frequency and cross-tabular analyses as well as chi-square test of significance. The study found that slightly less than three-tenths of widowed women are „old-old‟ (75+ years). On the other hand, three-fifths of elderly belonged to most backward / backward caste and majority (63%) of them illiterates. About two-fifths (42%) of the elderly widowed women are living with married son. The differentials of elderly living alone vs with children are mostly in expected direction and highly significant (p<0.001) with an increase in the number of earning members in the family, number of children living in the same area / city as well as those who belonged to the households of high standard of living. On the other hand, the percentage of widowed elderly who live alone has shown a clear increasing pattern with an increase in occupational status and instrumental activities of daily living scale. Further, it is noticed that the elderly who are living alone is higher among those who are feeling „unhealthy‟ as compared to those elderly widowed women as „healthy‟. All these percentagedifferentials are also turned out as significant at different levels of extent (p<0.001 or p<0.05).Based on these findings a few policy implications have been postulated.
The impact of enterprise systems in management decision making
Authors: C Muthuvelayutham , T Sugantha lakshm
Published: March 2020

An Enterprise Resource Planning (ERP) system is composed of a basic transactional system and a management control system. Sammon et al. (2003) describesthese 2 components of ERP systems as the solution to “operational” integration problems and “informational” requirements of managers. Thus, the extreme standardisation of business process inherent in ERP systems creates huge volumes of data without providing a clue for how to exploit it and may therefore not beneficial from a decision-making point of view. In this paper, decision-making theory and models are reviewed, focusing on how an ERP implementation might impact on these constructs. This paper is an analysis about centralisation of decision making in an organisation and its impact on performance at a local level.
Effects of insurgency on traditional cattle feedlot management in maiduguri, nigeria
Authors: Bukar Muhammad Modu
Published: March 2020

The outbreak of insurgency in Maiduguri in 2009 and the subsequent targeted attacks on the lives and property of innocent civilians including livestock farmers has had a severe disruptive effect on Agriculture in northeast Nigeria. Efforts aimed at economic recovery and rehabilitation of the conflict ravaged regions requires information and an understanding of how the insurgency affected the communities so that aid aimed at financial inclusion could be appropriately directed. Thus, this study was designed to highlight the traditional feedlot cattle management in Maiduguri. The price of the cattle and feed materialsas well as profit in 2008 and 2015 were compared. It was found that the preferred choice of feedlot cattle is the non- indigenous Ambala cattle breed. Compared with 2008, the cost of the bulls and feed materials had significantly increased in 2014 and 2015 but the average profit remained unchanged. The farmers earned up to ₦40,000 profit per head of cattle. It is recommended that financial inclusion strategies intended for post-insurgency socio-economic recovery in Maiduguri and other affected areas of north-eastern Nigeria should include building of secure feedlot cattle enclosures with proper facilities for tethering, feed storage,and waste disposal. Quality assurance and hygienic management of such places should be according to global best practices. In addition, establishment of a meat processing plant as well as provision refrigerated transportation trucks can help the farmers to maintain their profit margin and avoid stress associated with road transport of live animals. The government should design and implement a program to breed Ambala cattle using Assisted Reproductive Technology for the development Nigeria’s beef industry.
基于能值生态足迹的广西城镇化质量与生态环境承载力耦合分析
Authors: 向 开成 , 唐 莉
Published: March 2020

本文以广西壮族自治区为研究对象，采用了能值生态足迹法，计算了广西 2007-2017 年间能值生态足迹和能值生态承载力，并计算了生态赤字水平，然后采用耦合分析法，构建了新型城镇化质量和生态环境可持续能力指标体系，并计算了广西2007-2017 年间新型城镇化质量和生态环境承载力耦合度指数。结果显示：①广西 2007-2017 年间生态承载力呈上下波动状态，变化的幅度不是很大，人均生态承载力波动幅度为人均5.9hm2，人均生态足迹呈增长趋势，由2007年的人均生态足迹3.67hm2②广西生态赤字 2007 年为 2.01hm2，到 2017 年为 2.96hm2, 处于强不可持续阶段③ 2007 年广西新型城镇化质量与生态环境承载力协调耦合度低，处于拮抗阶段，此后进入高水平的耦合协调阶段。
社会文化何以成就大学生的企业家精神：考虑社会资本与心理资本的中介作用
Authors: 王 征 , 许 佳阳 , 冯 淑睿 , 贺 澜倩 , 谭 嘉颖 , 罗 怡姗
Published: March 2020

为探讨社会文化对大学生企业家精神的影响机制，并检验社会资本与心理资本的中介效应。本研究采用问卷调查法，对404名大学生进行调查，借此构建四个变量之间的关系模型，探索大学生企业家精神的影响机制。结果表明（1）社会文化影响心理资本、社会资本和企业家精神。（2）社会资本和心理资本在社会文化与企业家精神关系间起部分中介作用，中介作用分别占总效应的18.61%和48.76%。根据以上研究结果，为大学生企业家精神培养路径提供建议。
如何有效提高北方地区造林质量
Authors: 王 丹丹 , 马 姝红
Published: March 2020

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Research on Internet Public Opinion and Social Governance in the Big Data Era
Authors: Wu Shengliang
Published: March 2020

In the development of modern society, the Internet public opinion presents the characteristics of cross-platform, multi-node, complex, etc. There are quite a few types of online public opinion with short duration, and the content has certain conflicts. The network opinion has greatly changed in the development of society, but there are still many pressures of public opinion. The paper studies the Internet public opinion and social governance in the big data era, and hopes to realize the scientificity of social governance.
HUBUNGAN TIMBAL BALIK ANTARA ARUS MASUK FOREIGN DIRECT INVESTMENT DAN HUMAN CAPITAL DI INDONESIA DAN INDIA
Authors: Ramzy Raden Fiat Mahadhika
Published: March 2020

Foreign Direct Investment (FDI) benefits the host country by technology transfer and spillover effect toward its workforce. Meanwhile, the quality of human capital (HC) in the host country may attract FDI. This study aims to examine the relationship of FDI inflow and the quality of HC in Indonesia and India and to investigate FDI orientation. Applied two-stage least square to time series data of the year 2000-2015, the result shows a causal relationship between FDI and HC in Indonesia, but one-way relationship from FDI to HC in India. Government spending on education and health has positive effects on HC in both countries. In Indonesia, FDI is positively affected by HC and growth, while in India, only by country risk index.Keywords: Foreign Direct Investment, human capital, two stage least square