bluuebunny/crossref_metadata_2025 huggingface dataset:
FREKUENSI MAKAN DAN AKTIVITAS FISIK DENGAN PERSENTASE LEMAK TUBUH PADA MEMBER AKTIF DI EMPIRE GYM
Authors: Ayu Ningsih Ni Luh Rahma , Septriana Septriana , Prasetyaningrum Yunita Indah
Published: January 2025

Latar belakang: Obesitas adalah seseorang yang mempunyai kelebihan berat badan karena terdapat penumpukan lemak dalam jaringan subkutan, persentase lemak tubuh dapat dipengaruhi oleh faktor gaya hidup yaitu frekuensi makan dan aktvitas fisik. Tujuan: Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan terdapat hubungan antara frekuensi makan dan aktivitas fisik dengen persentase lemak tubuh pada member aktif di Empire Gym Maguwoharjo Yogyakarta. Metode :  Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross-sectional. Subjek penelitian ini adalah member aktif di Empire Gym Maguwoharjo Yogyakarta yang berjumlah 67 responden. Teknik pengambilan sampel menggunakan purposive sampling. Instrumen penelitian menggunakan kuesioner FFQ untuk mengukur frekuensi makan, kuesioner GPAQ untuk mengukur aktivitas fisik, dan BIA untuk mengukur persentase lemak tubuh. Analisa data menggunakan uji Fisher’s Exact Test. Hasil: Sebagian besar responden memiliki frekuensi makan dalam kategori rendah (49,3%), aktivitas fisik dalam kategori tinggi (70,1%), lemak tubuh dalam kategori overfat (80,6%). serta diperoleh nilai p-value sebesar 0,668 untuk frekuensi makan dengan lemak tubuh. Hubungan antara aktivitas fisik dan frekuensi makan dengan persentase lemak tubuh memiliki nilai p-value sebesar 0,668 dan 0,330. Nilai tersebut berarti bahwa tidak terdapat hubungan yang signifikan antara frekuensi makan dan aktivitas fisik dengan persentase lemak tubuh pada member aktif di Empire Gym Maguwoharjo Yogyakarta. Kesimpulan: Tidak terdapat hubungan antara frekuensi makan dan aktivitas fisik dengen persentase lemak tubuh pada member aktif di Empire Gym Maguwoharjo Yogyakarta.
Analisis Pengaruh Cash Ratio dan Claim Expense Ratio terhadap Kinerja Keuangan Perusahaan Asuransi Jiwa di BEI Tahun 2020-2023 dengan Kebijakan Dividen sebagai Mediasi
Authors: Huda Pratiwi Nur , Albart Nicko
Published: January 2025

Penelitian ini bertujuan untuk menganalisis pengaruh cash ratio dan claim expense ratio terhadap kinerja keuangan perusahaan asuransi jiwa yang terdaftar di Bursa Efek Indonesia (BEI) periode 2020–2023, dengan kebijakan dividen sebagai variabel mediasi. Penelitian ini menggunakan pendekatan kuantitatif dengan teknik analisis path. Populasi penelitian adalah perusahaan asuransi jiwa di BEI, dengan sampel sebanyak 18 perusahaan yang dipilih menggunakan metode purposive sampling. Data sekunder berupa laporan keuangan dan laporan tahunan diperoleh dari situs BEI. Hasil penelitian menunjukkan bahwa: (1) Cash ratio berpengaruh signifikan dan positif terhadap dividend payout ratio (DPR); (2) Claim expense ratio juga berpengaruh signifikan dan positif terhadap DPR; (3) Cash ratio berpengaruh signifikan dan positif terhadap return on assets (ROA); (4) Claim expense ratio tidak berpengaruh signifikan dan negatif terhadap ROA; (5) DPR berpengaruh signifikan dan positif terhadap ROA; (6) DPR memediasi secara signifikan pengaruh cash ratio terhadap ROA; dan (7) DPR memediasi secara signifikan pengaruh claim expense ratio terhadap ROA. Penelitian ini memberikan implikasi teoretis dengan memperluas pemahaman mengenai hubungan antar variabel keuangan pada sektor asuransi jiwa, serta implikasi praktis berupa panduan bagi manajer keuangan dalam pengambilan keputusan terkait pengelolaan rasio keuangan dan kebijakan dividen. Penelitian selanjutnya disarankan untuk memperluas sektor perusahaan yang diteliti dan mempertimbangkan metode analisis alternatif untuk memperkaya wawasan penelitian.
Pelatihan Desain Logo untuk UMKM dan Crafting Manik-Manik bagi Anak SD di Kelurahan Pengantungan sebagai Upaya Meningkatkan Pemberdayaan Ekonomi dan Kreativitas Komunitas
Authors: Listriyani Dwi , Mutiya Merlen , Apriani Murtika , Yanti Sabrina , Ramadhan Gilang , Widiarti Diyas
Published: January 2025

Kegiatan pengabdian ini merangkum kegiatan Community-Based Development (CBD) bertujuan mencapai pemberdayaan ekonomi kelompok masyarakat lokal dan meningkatkan kapasitas individu, kelompok, atau komunitas dalam mengelola sumber daya dan memecahkan masalah secara mandiri, sehingga tercipta kemandirian yang berkelanjutan. kegiatan ini dilaksanakan di Kelurahan Pengantungan, Kecamatan Ratu Samban, dengan fokus pada pelatihan pemberdayaan masyarakat. kegiatan pengabdian ini bertujuan untuk meningkatkan kapasitas pelaku UMKM melalui pelatihan desain logo sebagai langkah strategis memperkuat branding produk, serta mengembangkan kreativitas dan jiwa kewirausahaan pada anak-anak usia sekolah dasar melalui pelatihan crafting manik-manik. Pelaksanaan kegiatan melibatkan berbagai pendekatan, termasuk observasi, wawancara, dan partisipasi aktif masyarakat. Hasilnya menunjukkan adanya peningkatan keterampilan peserta, baik dalam pembuatan logo yang lebih profesional maupun dalam memproduksi kerajinan tangan yang bernilai ekonomis. Selain itu, program ini juga berhasil meningkatkan kesadaran masyarakat akan pentingnya branding dan kewirausahaan sebagai upaya pemberdayaan ekonomi lokal. evaluasi terhadap pelaksanaan program kegiatan pengabdian, masyarakat umkm masih dalam tahap pendampingan lanjutan, sehingga ada tantangan dan keterbatasan akses teknologi dan sumber daya. pendampingan lanjutan di lakukan secara sistematika via online. program ini memberikan dampak positif yang signifikan bagi masyarakat. Rekomendasi mencakup pengembangan program berkelanjutan, peningkatan dukungan teknologi, dan penguatan branding produk masyarakat umkm kelurahan pengantungan.
Pengaruh Penerimaan Pajak Kendaraan Bermotor, Denda Pajak, dan Bea Balik Nama Kendaraan Bermotor terhadap Pendapatan Asli Daerah Kabupaten Deli Serdang
Authors: Jayanti Sri , Wirananda Henny Andriyani
Published: January 2025

The purpose of this study was to determine the effect of Motor Vehicle Tax, Tax Fines and Motor Vehicle Transfer Fees on the Original Regional Income of Deli Serdang Regency, and to analyze the effect of Motor Vehicle Tax, Tax Fines and Motor Vehicle Transfer Fees together on the Original Regional Income of Deli Serdang Regency in 2019-2022 in monthly. The data collection technique used in this study was a documentation study. This study used multiple linear regression analysis methods. The results of the study showed that Motor Vehicle Tax had an effect on the Original Regional Income of Deli Serdang Regency, Tax Fines had a significant effect on the original regional income of Deli Serdang Regency and Motor Vehicle Transfer Fees had no effect on the Original Regional Income of Deli Serdang Regency. Motor Vehicle Tax, Tax Fines and Motor Vehicle Transfer Fees together had an effect on the Original Regional Income of Deli Serdang Regency. Motor Vehicle Tax, Tax Fines and Motor Vehicle Transfer Fees have a strong relationship to Regional Original Income, which is 0.814, or Motor Vehicle Tax, Tax Fines and Motor Vehicle Transfer Fees to Regional Original Income of Deli Serdang Regency, which is 81.4% while the remaining 18.6% is influenced by other factors not included in this study.
Implementasi Manajemen Strategi Bank Syariah Indonesia (BSI) Tbk, Cabang Banda Aceh dalam Meningkatkan Kualitas Mutu Pelayanan Nasabah
Authors: Harahap Wahyuni , Zuliani  , Fajri Ikhsan , Hamid  , Mauliza Putri
Published: January 2025

Penelitian ini berjudul” Implementasi Manajemen Strategi PT. Bank Syariah Indonesia (BSI) Tbk, Cabang Banda Aceh Dalam Meningkatkan Kualitas Mutu Pelayanan Nasabah. Seiring ketatnya persaingan dunia perbankan masa sekarang ini, perbankan syariah khususnya Bank Syariah Indonesia ingin memberikan implementasi manajemen strategi dala meningkatkan mutu kualitas pelayanan, khususnya dalam melayani kebutuhan nasabah, dengan pelayanan yang baik maka nasabah maupun masyarakat akan merasa puas dan percaya pada hal yang penting bagi bank, bentuk pelayanan yang di berikan termasuk menerima keluhan atau masalah yang di hadapi oleh seorang nasabah. Pihak Bank Syariah Indonesia harus pandai dalam mencari jalan keluar atau manajemen strategi dalam memanage (menyelesaikan) masalah yang dihadapi oleh nasabahnya. Berdasarkan amatan awal penelitian ini di lakukan secara observasi secara umum pada PT. Bank Syariah Indonesia (BSI) Cabang Banda Aceh. Namun ada beberapa kendala yang terjadi, di antaranya dalam hal kekurangan pelayanan yang di lakukan dilihat dari adanya beberapa  jaringan operasional Bank syariah Indonesia yang belum maksimal, tingkat kemandirian, kualitas maupun Kuantitas dari beberapa karyawan yang masih bermasalah, yang ditandai dengan adanya kegagalan sistem input data, transaksi, yang sempat terjadi dalam tahun terakhir ini, hal ini berdampak pada kurang efektifnya pelayanan kepada nasabah oleh sebagian kecil karyawan PT. Bank Syariah Indonesia (BSI) Cabang Banda Aceh. Berdasarkan fenomena yang terjadi di lapangan maka tujuan dari penelitian ini yaitu; “Untuk mengetahui Manajemen Strategi Bank Syariah Indonesia (BSI) Tbk Unit Peunayong Cabang Banda Aceh Dalam meningkatkan Mutu Kualitas Pelayanan Nasabah dengan melakukan telaah kepustakaan melalui literarur karya tulis ilmiah, buku-buku dan literarur lainyan yang relevan dengan penelitian.
Sentiment Analysis of the Tapera Law on Platform X Using Naive Bayes Algorithm
Authors: Bimantoro Dava Sevtiandra , Rasiban
Published: January 2025

The implementation of the 2016 Public Housing Savings Law (UU Tapera) aims to help legal and informal workers have decent houses through the management of housing savings funds by BP Tapera. However, when implemented, this program experienced obstacles amidst various problems including the transparency of the fund collection and management system, the unevenness of benefit provision, and variations in public perception. Sentiment analysis was conducted on Twitter data for sentiment regarding the Tapera Law to obtain public perception with Naïve Bayes. This approach classifies sentiment into positive, negative, and neutral. The accuracy of the Analysis Results was 62.47% (343 negative sentiments, 23 neutral, and finally 32 positive sentiments). The public mostly has negative sentiment towards the Tapera Law, because many of them are afraid of losing justice and effectiveness with this policy. These results underline the need to intensify transparency and communication of the benefits of the Tapera Law and its mechanisms to increase public acceptance and trust.
Information System for Managing Incoming and Outgoing Mail at the Central Statistics Agency of West Sumba Regency
Authors: Bora Emilia Krista , Janga Adelbertus Umbu , Adis Alexander
Published: January 2025

BPS West Sumba Regency still manages mail manually, facing issues of efficiency, transparency and accuracy. Manual processes risk document loss and recording errors. This research aims to identify problems and recommend an integrated information system. This innovation is expected to increase productivity, reduce errors, and speed up decision-making at BPS. Rapid Application Development (RAD) is a software development model that focuses on accelerating processing time. This approach combines object-oriented development methods and structured techniques to accelerate the process of creating a system or application. The research showed that the implementation of the new information system at BPS West Sumba Regency improved operational efficiency. Mail processing time dropped from 3 hours to 1 hour, and the error rate was reduced from 15% to 2%. User satisfaction increased from 60% to 90%, which had a positive impact on employee motivation. User satisfaction increased from 60% to 90%, which had a positive impact on employee motivation and collaboration. The system also strengthened and improved transparency.
Improved Edge Detection using Morphological Operation to Segmentation of Fingernail Images
Authors: Kurniastuti Ima , Herlambang Teguh , Wulan Tri Deviasari , Magfira Dike Bayu , Meutia Nur Shabrina , Saputro Hendik Eko , Soraya Sabrina Ifahdini
Published: January 2025

Accurate segmentation of fingernail images is essential for biomedical applications like dermatological diagnostics and nail disease assessments. This study compares traditional methods (Sobel and Canny edge detectors) with an improved method using adaptive thresholding and morphological closing for fingernail image segmentation. The methodology includes data collection, preprocessing, edge detection, segmentation, and evaluation. A dataset of 500 fingernail images (free of nail polish) was captured using a digital camera. Preprocessing involves grayscale conversion to simplify analysis and Gaussian smoothing to reduce noise while preserving key features. For segmentation, thresholding and K-means clustering isolate the fingernail from the background. Evaluation combines qualitative and quantitative analyses. Qualitative results demonstrate that the improved method consistently outperforms traditional techniques under diverse conditions. Quantitative evaluation, based on accuracy, recall, F1 score, and Intersection over Union (IoU), further supports these findings. The Sobel method achieves 0.80 accuracy, 0.77 recall, 0.87 F1 score, and 0.77 IoU. The Canny method achieves 0.82 accuracy, 0.78 recall, 0.88 F1 score, and 0.78 IoU. In contrast, the improved method achieves 0.97 accuracy, 0.98 recall, 0.99 F1 score, and 0.98 IoU. The results clearly show that the improved method, using adaptive thresholding and morphological closing, provides superior segmentation performance. Additionally, the approach remains computationally efficient, making it suitable for real-time applications in medical diagnostics.
Refining Diabetes Diagnosis Models: The Impact of SMOTE on SVM, Logistic Regression, and Naïve Bayes
Authors: Wibowo Arief , Masruriyah Anis Fitri Nur , Rahmawati Selly
Published: January 2025

The accurate classification of diabetes remains a significant challenge in medical diagnostics, particularly when dealing with imbalanced datasets. This study examines the impact of the Synthetic Minority Over-sampling Technique (SMOTE) on the performance of three machine learning algorithms: Support Vector Machine (SVM), Logsistic Regression, and Naïve Bayes. Initially, the models were evaluated on the original imbalanced dataset, with AUC values of 0.598 for SVM, 0.622 for Naïve Bayes, and 0.613 for Logistic Regression, reflecting the challenges posed by class imbalance. To address this issue, SMOTE was applied to balance the dataset by oversampling the minority class. After applying SMOTE, the models showed significant improvements in performance, with AUC values increasing to 0.991 for SVM, 0.987 for Logistic Regression, and 0.986 for Naïve Bayes. These results demonstrate SMOTE's effectiveness in enhancing model performance by mitigating the impact of imbalanced data, especially in the context of diabetes classification. Although the improvements in AUC were notable, it’s important to recognize the influence of data balancing on the models' behavior. These findings emphasize the need for careful handling of imbalanced datasets when developing machine learning models for medical diagnosis. This study provides valuable insights into the role of oversampling techniques like SMOTE in improving predictive accuracy for diabetes, a critical step toward more reliable medical diagnostics.
The Comprehensive Approach of Military Strategic Operations Planning and its support by Artificial Intelligence
Authors: Szabadföldi István , Négyesi Imre
Published: January 2025

Military operations are always preceded by political decisions and the transition to military means in the management of conflicts in order to pursue political goals takes place in either national or alliance context. Information operations, all-source intelligence as tools for intelligence and counter-intelligence play a key role in the planning of military operations. The last two decades have brought with them the explosive spread of digital technologies. The application of communication technology (5G), sensor systems, IoT (Internet of Things) produces a huge amount and multiple types of data, from which Big Data analytic systems and algorithms using Artificial Intelligence (AI) gain usable information. Accordingly, applications supported by AI play an increasingly important role in military operations on strategic, operational, and tactical levels. The analysis of data collection from all-source intelligence – especially SIGINT (Signal Intelligence) and OSINT (Open-Source Intelligence) and the AI-supported analysis is a key to success for Effect based Operations (EBO).
The Role of the Armed Forces in Counterterrorism
Authors: Kiss Álmos Péter
Published: January 2025

The armed forces are organized, trained and equipped to fight the external enemies of the state, and they have a role to play in maintaining internal security as well. However, such “military assistance to the civil power” missions are fraught with risks. This paper addresses three of those risks. The armed forces’ national defence capabilities are affected and their budget is burdened with non-military expenditures. Performing law enforcement duties (especially without adequate training beforehand) carries with it the risk of poisoning the civil-military relationship for a long time – and once it is lost, it is very difficult to regain the trust of the population. Employing the armed forces in the counterterrorist role may also turn a dangerous, but manageable terrorist threat into a deadly, no-holds-barred armed conflict. In spite of the many potential problems, the armed forces do have a role to play in counterterrorism.
Neo-Eurasianist Russian Geopolitics and the New Empire-Building Distribution Russian-Chinese Relations: “Utilitarianism or World Politics Tandem?”
Authors: Haiszky Edina Julianna
Published: January 2025

Both the Russian Federation and the People’s Republic of China are defining and unique features on the world security map. The aim of this analysis is to review the mainschools of Russian geopolitical thought, with a particular focus on neo-Eurasianism, and to take stock of the extent to which the ideological community with the PRC persists and the impact on the relationship of the two parties of the decline of Russian influence in the Central Asian region and the rise of China in the last year, as a result of the Russian-Ukrainian war and Russia’s turn to the West.
Prescribing trend of drugs for the treatment of diabetes in the Local Health Service Tuscany Centre from 2020 to 2023: between “Diabetes Project” and AIFA Nota 100
Authors: Peluso, E.
Published: January 2025

Nel 2019 la ASL Toscana Centro (TC) ha promosso il “Progetto Diabete” diretto ai medici di medicina generale (MMG) per favorire la deprescrizione di sulfaniluree (SU) e glinidi a vantaggio dei nuovi ipoglicemizzanti. Tale intervento si è rivelato particolarmente utile ed è stato ulteriormente potenziato nel 2022 a seguito dell’entrata in vigore della AIFA Nota 100, che ha consentito la prescrizione dei più recenti ipoglicemizzanti ai MMG così come a specialisti quali cardiologi, nefrologi e internisti. L’obiettivo del presente studio è stato valutare l’impatto del progetto ed analizzare il trend prescrittivo di SU, glinidi e altri farmaci ipoglicemizzanti con effetto di prevenzione del danno d’organo. Nella ASL TC il diabete trattato farmacologicamente risulta avere una prevalenza in crescita negli anni dal 2020 al 2023, passando dal 5,5% al 6,2% con prevalenza nel sesso maschile. Mediante la lettura ottica delle ricette sono state tracciate le erogazioni relative a tutte le classi di farmaci antidiabetici (classe ACT A10). I dati mostrano come l’uso delle SU ha subito una riduzione del 75% dal 2020 al 2023; contestualmente si è apprezzato un significativo incremento per le nuove classi di farmaci, maggiore per gli SGLT2i (+ 54%), dato in linea con quello nazionale. Notevole il dato di aumento anche per i GLP-1 RA (+ 51%), mentre i DPP4i sono rimasti sostanzialmente stabili, rappresentando nel 2023 il 14% dei farmaci ipoglicemizzanti prescritti. Minimo invece l’incremento delle associazioni precostituite (SGLT2i+DDP4i). PAROLE CHIAVE linee-guida; Nota 100; farmaci ipoglicemizzanti; andamento prescrittivo.
One Health and nutrition
Authors: De Carli, L.
Published: January 2025

Il termine One Health racchiude in sé il concetto per cui la salute dell’uomo, degli animali e del Pianeta Terra siano strettamente interconnesse l’una con l’altra. I fattori coinvolti nella preservazione e promozione di tale concetto sono molteplici. Tra questi, uno dei maggiori determinanti è l’alimentazione. Infatti, la ricerca scientifica ha mostrato come la dieta sia uno dei principali elementi per il contrasto di numerose patologie, soprattutto quelle definite croniche non trasmissibili, come diabete, ipertensione, patologie cardiovascolari, che rappresentano, tutte insieme, una delle principali cause di morte a livello mondiale. Allo stesso tempo, la catena alimentare è tra i maggiori responsabili della produzione di gas climalteranti, di consumo di suolo e di utilizzo di acqua. All’interno di questo scenario, ben si comprende come sia necessario adottare stili di vita e pattern dietetici che permettano di promuovere contemporaneamente la salute dell’uomo, il benessere animale e la salute del nostro Pianeta. Due esempi in questo senso sono la Dieta Planetaria e la Dieta Mediterranea, che verranno brevemente presentate ed analizzate sotto i diversi profili sopracitati. PAROLE CHIAVE nutrizione; pianeta; sostenibilità; salute.
Hubschraubertransport bei Patienten mit ARDS.
Authors: Schedler Olaf , Hirsch Steffen , Handschack Hartmut
Published: January 2025

Intensivtransporte mit Hubschraubern finden in der Indifferenzzone von 1000 ft bis 4000 ft (300 m bis 1220 m) statt. Während der Luftdruck (PBARO) in Meereshöhe 760 mmHg beträgt, nimmt er mit zunehmender Flughöhe ab. Dabei verändert sich der Sauerstoffpartialdruck der Alveole (PAO2) am deutlichsten. Wir untersuchten die Veränderungen des PAO2 und des PaO2 an 10 Patienten mit ARDS während Hubschrauberintensivtransporten. Weiterhin wurden die Parameter CaO2, QS/QT und der Oxygenierungsindex berechnet. In der Flughöhe von 2000 ft reduzierte sich, trotz kalkulierter Erhöhung des PAO2 von 33 mmHg, der arterielle PaO2 um 15 mmHg. Die Ursache dafür liegt in Perfusionsveränderungen schlecht ventilierter Lungenareale während der Transportphase, welche durch eine Zunahme des intrapulmonalen Shunt (QS/QT) gekennzeichnet sind. Hubschraubertransporte mit ARDS Patienten bleiben eine individuelle Entscheidung. Grundlagen liegen in der Bestimmung des PaO2 und des Oxygenierungsindex.
Journal Maritime Medozin
Authors: Schedler Olaf
Published: January 2025

Im Journal Maritime Medizin werden Artikel des Berlin Medical Journal zusammengefasst, welche sich mit dem Schwerpunkt beschäftigen. Neben der Beschreibung neu entwickelter Ausbildungsprinzipen für MedizinerInnen in der Schifffahrtsmedizin werden Rettungs- und Evakuierungsgeräte vorgestellte, welche die Möglichkeit der Rettung in See besitzen. Mit den diagnostischen Maßnahmen der fokussierten Sonographie und der dynamischen Telemedizin kann es nach den Publikationen im BerMedJ bedeuten, die Qualität der medizinischen Diagnostik und Behandlung zu verbessern. Ein Fallbericht, welcher im Zusammenhang mit dem Einsatz neuer Medizintechnik und eines optimalen Behandlungsmanagement einhergeht, stellt eine erfolgreiche Reanimation mittels Feedbacksystems an Bord eines Großseglers dar.
Ein Fall zum Polterabend. Ein klarer Fall.
Authors: Schedler Olaf
Published: January 2025

Of the estimated annual 120000-165000 syncopal events in Germany not all find their way through the emergency service in the hospital. Most patients with syncope treated or admitted outpatients with these symptoms. During the approximately 45,000 rescue operations per year in Brandenburg, the rescue service personnel diagnosed between 2000 to 6000 times the diagnosis syncope. Surely there can be no rescue medicine with regard to the use of calculation as medical data for emergency medicine prescribed country or across countries are missing. An extrapolation of the Working Group in Brandenburg active emergency physicians (AGBrN) on the data basis of the ADAC air rescue GmbH MÃ¼nchen found that are carried out up to 12% of the German air rescue operations due to syncope. This corresponds to Germany's 4200 air rescue operations.
Signal Extraction Technology in Aviation Medicine: Perfusion-Independent Determination of Peripheral Oxygen Saturation
Authors: Schedler Olaf , Boye Renate
Published: January 2025

During air rescue, the technical limitations of conventional pulse oximetry for cases of centralised circulation and shock are amplified due to additional vibration and hypobaric conditions. The current study of 50 patients evaluated different methods of peripheral oxygen saturation (SpO2) measurement at an average altitude of 2200 feet. Signal extraction technology (SET) measured markedly higher SpO2values compared to conventional methods(97% vs. 76%). The SET measurements also took considerably less time (30 vs. 90 seconds), regardless of perfusion status. In 20% of the patients, conventional pulse oximetry yielded no usable measurement.SET oximetry also allows calculation of the perfusion index (PI). In our data, PI values correlated with blood pressure (r=-0.4) and the shock index (r=0.82). In conclusion, the SET Rad5 Oxymeter gives a more reliable measurement than conventional pulse oximetry in cases of patient movement, vibration, decreased perfusion, and shock.
Sonographieuntersuchungen im maritimen Setting
Authors: Fischer Va
Published: January 2025

Durchführung einer fokussierten sonographsichen Untersuchungen als differentialdiagnostisches Untersuchungselement auif einer Bark im internationalen Seegebieten. An 16 Freiwilligen wurden fokusierte abdominelle Untersuchungen durchgeführt. Die Sonograohie biete eine diagnostische Entscheidungshilfe in der Seefahrt und kann durch geschulte ärztliche Kollegen eingesetzt werden.
Die Effektivität und Effizienz mechanischer Thoraxkompressionen anhand von Feedbackmecha-nismen
Authors: Schedler Olaf
Published: January 2025

Zur Analyse von Kom-pressionstiefe, Kompressionsrate und dem Trend der Freigabegeschwindigkeit (Thoraxentlastung) von mechanischen Thoraxkompressionsgeräten, nutzen wir einen Monitor der X Serie der Firma Zoll mit Feed-backdefibrillationselektroden und der Auswertungs-software Case Review sowie eine Reanimations-puppe Mini Anne der Firma Laerdal. Zur Testung kamen die Geräte Lucas 1, Lucas 2, Au-topulse und Corpuls CPR zur Anwendung.
Die Volumensubstitutionstherapie im Luftrettungsdienst
Authors: Schedler Olaf
Published: January 2025

In der vorliegenden Arbeit werden anhand von Einsatzdaten aus dem Luftrettungdienst der Jahre 1999 bis 2005 eines Primärhubschraubers (Christoph 33) und eines Intensivhubschraubers (Christoph 71) bei Traumapatienten hinsichtlich des Voulmensubstitutionsmanagemnet ausgewertet. Es wurden 10423 Originaldatensätzen ausgewertet und 1117 Einsatzdaten konnten zur Analyse herangezogen werden. Das entspricht 10,72 % aller Einsätze. In 2029 Einsätzen lagen 30% Extremitätenverletzungen, 24% Schädel-Hirn-Trauma, 16% Wirbelsäulenverletzungen, 11% Thoraxtraumata, 8% Gesichtsverletzungen, /% wichteilveletzungen sowie 4% Beckentraumata vor. In der Erstbehandlung wurden 547 kristalline -, 529 kolloidale- sowie 29 kombinierte Infusionen druchgeführt. In der Gruppe der kristallienen Infusionen sank der TRISS Score um 1,63 Punkte. In der Gruppe der kolloidalen Infusionstherapie stieg der TRISS Score um 0,22 Punkte. In der Kombinationstherapie von kristallien un kolloidalen Lösungen sank der TRISS Score um 5,78 Punkte.
Molecular detection of Streptococcus agalactiae in pregnant women and percentage of vertical transmission to their neonates in Babylon province
Authors: Marhash Ali D. , Nabat Zainab N. , Abbas Nawras A.
Published: January 2025

Introduction. Streptococcus agalactiae are gram-positive, non-motile and encapsulated cocci. On blood agar, they produce an narrow zone of beta-haemolysis. This pathogen causes invasive bacterial diseases in newborns, including sepsis, meningitis, septicaemia, and pneumonia, when transmitted from infected mothers. Since S. agalactiae is a pathogen of primary concern for public health, this research has been conducted on it.
The objective of the study is the isolation and molecular detection of virulence gene of S. agalactiae group B (GBS), and evaluation of the percentage of mother-to-child transmission of the pathogen.
Materials and methods. A prospective cohort study was designed that included 300 pregnant women who were at more than 35 weeks of pregnancy. The gynaecologist collected 300 vaginal swabs from all participants in this study and followed up on all GBS-positive pregnant women after delivery to take swabs from their neonates. Traditional microbiological and molecular approaches were used to study isolated bacteria.
Result. Sixty (20%) of three hundred pregnant women and 16 (26.6%) of their newborns were enrolled in this study. GBS was detected via culture methods and was confirmed by PCR with primers employed for the detection of atr gene (housekeeping gene). Positive isolates were 100% susceptible to antibiotics such as ceftriaxone, penicillin, and vancomycin, 93% were sensitive to chloramphenicol, 83% to erythromycin, and only 13% to tetracycline.
Conclusion. Our data showed a high frequency of GBS infection in pregnant women and their newborns. A mandatory screening test and preventative medicine should be adopted to minimize the potentially fatal repercussions of this sickness.
Characteristics of the monkeypox virus isolate obtained from the first patient in Russia and its sensitivity to 7-[N-(4-trifluoromethylbenzoyl)-hydrazinocarbonyl]-tricyclo-[3.2.2.0^2,4]non-8-en-6-carboxylic acid
Authors: Ovchinnikova Alena S. , Odnoshevsky Dmitrii A. , Kabanov Alexey S. , Bodnev Sergey A. , Pyankov Oleg V. , Os'kina Oksana P. , Sivay Maria V. , Bespalov Andrey V. , Tregubchak Tatyana V. , Shishkina Larisa N. , Taranov Oleg S. , Zolin Vladimir V. , Sergeev Artemiy A. , Agafonov Alexander P.
Published: January 2025

Introduction. Since early May 2022, more than 90,000 cases of monkeypox virus infection have been reported in more than 70 countries around the World. This is the largest outbreak of monkeypox ever recorded outside of Africa.
The aim of the study is to confirm the first case of monkeypox in Russia, to isolate and sequence a new strain of monkeypox virus (MPXV), and to assess its sensitivity to the 7-[N-(4-trifluoromethylbenzoyl)-hydrazinocarbonyl]-tricyclo-[3.2.2.0^2,4]non-8-en-6-carboxylic acid (NIOCH-14) antipox drug.
Materials and methods. The biological materials obtained from the affected area of the skin (contents of vesicles), a nasopharyngeal smear, sputum and venous blood from a patient with suspected monkeypox were used. The disease was confirmed by PCR followed by determination of the nucleotide sequence of viral DNA by sequencing. Isolation of the new MPXV strain from clinical samples was carried out in Vero E6 cells. The antiviral effectiveness of NIOCH-14 against the new MPXV strain was assessed using an adapted spectrophotometric method.
Results. A diagnostic study of the biological samples of a patient who returned from a tourist trip to European countries with complaints of skin rashes all over the body revealed MPXV DNA. A new strain of MPXV was isolated from vesicles in Vero E6 cells, and the genomic sequence MPXV-pustule S45 was assembled using high-throughput parallel sequencing (NGS).
Discussion. The effectiveness of the finished dosage form of NIOCH-14 against the new strain of MPXV based on the results of determining the 50% virus inhibitory concentration (IC50) was 0.02 μg/mL, and the selectivity index (SI) was 15,000.
Conclusion. In this study, the pathogen of monkeypox was detected and identified using real-time PCR, NGS and electron microscopy, and the first imported case of this disease in Russia was confirmed. It has been proven that the drug NIOCH-14 exhibits high antiviral activity in vitro against the new MPXV strain.
Successful Surgery of a Pancreatic Insulinoma Misdiagnosed as a Neuropsychiatric Disorder for 9 Years: A Case Report
Authors: M Alahyane , H Boualam , S Ammar , S Ijdda , S Rafi , G El Mghari , N El Ansari
Published: January 2025

Insulinoma is a rare functional pancreatic neuroendocrine tumour that is usually sporadic and solitary. It can have a varied presentation. Neuroglycopenic manifestations of hypoglycemia due to insuline hypersecretion can mimic neurological or psychiatric disorders, thus often a diagnosis and treatment delay. Insulinoma is a potentially curable condition, but it can be fatal if left unrecognized. We report a case of A 45-year-old woman who had a 9-year delay before diagnosing insulinoma after being initially assessed with anxiety–depressive disorder. The case report below provides a detailed review of the diagnosis, tumour localization, and the successful surgical intervention implemented for the patient.
Association of sVCAM1 with interleukin -6 among rheumatoid arthritis patients
Authors: Obeid Shahad F. , Mohammed Wasnaa Jomaa , Ibrahim Noor Alhuda Kh
Published: January 2025

Symmetric synovitis is a histological characteristic of Rheumatoid Arthritis (RA), a systemic inflammatory connective tissue disease. An accelerated atherosclerosis process is the primary mechanism by which RA increases cardiovascular morbidity and mortality. The subject of the study consisted of two groups, the first group included 40 patients, all over the age of 18, with 35 females and 5 men participating also second group included 40 healthy controls who did not have any autoimmune disorders. The biochemical analyzer konelab prime 30ISE (bioMérieux france, craponne, france) was used to measure C-reactive protein and other parameters. The levels of inflammatory and immunological parameters, such as ESR, RF, CRP, and ACPA, were importantly higher in RA patients (52.37 ± 10.41, 44.28 ± 14.75, 57.00 ± 17.67, and 45.17 ± 12.3), respectively (p< 0.001). IL-10 pg/ml, IL-6 pg/ml, TNF-α pg/ml, and sVCAM ng/ml in RA patients (21.70 ± 3.08,54.42 ± 5.36,40.69 ± 7.26 and 7.12 ± 0.81) respectively (p< 0.001). The Logistic regression model shows that immunological parameters such as sVCAM correlate directly with IL-10 among RA patients. This result might refer to the fact that the RA condition enhances the production of sVCAM about IL-10. Also, it showed that the sVCAM directly correlates with IL-6 among RA patients. RA patients showed an association of sVCAM-1 directly correlated with IL-6. This result might refer to the fact that the RA condition enhances the production of sVCAM about IL-6.
Néhány szillogisztikus módozat érvényességének ellenőrzése a Venn-diagramok segítségével
Authors: Gergely P. Alpár
Published: January 2025

Dolgozatomban néhány szillogisztikus módozat Venn-diagram segítségével való ábrázolását szeretném bemutatni, illetve magyarázni szeretném azt, hogy bizonyos szillogisztikus módozatok esetében azok Venn-diagramos ábrázolásáról miért nem lehet leolvasni a szóban forgó módozatok érvényességét.
Pont és pontok
Authors: Ilyés Zalán-György
Published: January 2025

Kritikus pont. Szövegek a Kritikai elmélet és multikulturális
tanulmányok mesterképzőről. Szerk. Bíró Noémi, Szigeti Attila,
Szilágyi Botond. Pro Philosophia‒Egyetemi Műhely Kiadó,
Kolozsvár, 2023. 212 oldal
Szemléletváltó filozófiatörténet-írás
Authors: Veress Károly
Published: January 2025

Boros Gábor: Módszer, metafizika, emóciók. Megújuló alapvetés,
affektív közösségalkotás a 17. századi filozófiában. Akadémiai
Kiadó, Budapest, 2020. 250 oldal
Emberi, nagyon is emberi újra : A művészetvilág és az identitásdiskurzusok
Authors: Horváth Gizella
Published: January 2025

Az utóbbi fél évszázadban az identitás-diskurzusok növekvő jelentőségre tettek szert a művészet világában. Ezek a 70-es, 80-as évektől kezdődő diskurzusok a reprezentáció problémájára koncentráltak, így a művészet kiváló terepe lett az identitásprobléma tematizálásának. Jelen szöveg azt a hipotézist terjeszti elő, hogy ennek a növekvő tendenciának az kulminációját éljük, és a művészeti szcénán az identitásdiskurzusok, amelyek a csoportidentitásokra fókuszálnak, történelmi szükségszerűségből fakadón elveszítik domináns szerepüket. Jelenkorunk két kihívása – az ökológiai válság és a mesterséges intelligencia kutatások és alkalmazások robbanásszerű fejlődése (pl. képgenerálók, mint a MidJourney, vagy szöveggenerálók, mint a ChatGPT), aktuálissá teszik az ember újradefiniálását és általános újrapozícionálását az új technológiával kapcsolatban és az általa belakott világban.
EVALUASI KUANTITAS PENGGUNAAN OBAT ANTIASMA PADA PASIEN ASMA SERANGAN AKUT DI RUMAH SAKIT PARU RESPIRA YOGYAKARTA
Authors: Lolita Lolita , Lestari Mas Ulfah
Published: January 2025

Asma adalah penyakit inflamasi kronik saluran napas yang ditandai adanya mengi, batuk, dan rasa sesak di dada akibat penyumbatan saluran napas. Serangan asma bervariasi dari ringan sampai berat bahkan dapat bersifat fatal atau mengancam jiwa (Rai dan Artana, 2016). Sistem ATC/DDD adalah sebagai sarana penggunaan obat untuk meningkatkan kualitas penggunaan obat. Penelitian ini bertujuan untuk mengetahui kuantitas penggunaaan obat antiasma pada pasien asma serangan akut di RS Paru Respira Yogyakarta pada tahun 2016 dengan metode ATC/DDD.Penelitian ini merupakan penelitian observasional dengan pengumpulan data secara retrospektif pada tahun 2016. Analisa data dilakukan dengan dua cara, yaitu menghitung kuantitas penggunaan obat berdasarkan Defined Daily Dose (DDD) per 1000 KPRJ. Hasil diketahui terdapat 82 pasien yang termasuk inklusi dengan 129 kasus di RS Paru Respira Yogyakarta pada tahun 2016. Terdapat 62,20% perempuan dan 37,80% laki-laki. Karakteristik usia 36-45 tahun sebesar 52,40% lebih banyak terjadi asma serangan akut dibandingkan dengan usia 26-35 tahun sebesar 47,60%.Evaluasi kuantitas penggunaan antiasma pada pasien asma serangan akut yang paling banyak adalah formoterol sebesar 70,7/1000 KPRJ dan yang paling sedikit adalah fenoterol Hbr sebesar 0,02/1000 KPRJ.
PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN GAHARU (Aquilaria microcarpa Baill.) TERHADAP WAKTU PERDARAHAN PADA TIKUS PUTIH JANTAN GALUR WISTAR
Authors: Cahaya Noor , Fauzi Rakhmat , Hidayaturrahmah Hidayaturrahmah
Published: January 2025

Daun gaharu (Aquilaria microcarpa Baill.) memiliki kandungan senyawa flavonoid dan tanin yang berpotensi sebagai penyembuhan luka. Penelitian ini bertujuan untuk membuktikan pengaruh pemberian ekstrak etanol daun A. microcarpa terhadap waktu perdarahan tikus putih jantan yang diinduksi heparin. Dua puluh tikus jantan dibagi menjadi 5 kelompok. Kelompok I (kontrol negatif), II (kontrol positif), III, IV dan VÃƒâ€šÃ‚Â  (ekstrak etanol daun A. microcarpa dosis 75mg/KgBB, 100mg/KgBB dan 150mg/KgBB). Hewan uji diberi injeksi heparin selama 5 hari, kemudian diberi sediaan selama 6 hari dicatat waktu tiap 2 hari. Hasil penelitian menunjukkan persentase penurunan waktu perdarahan yaitu 41.74%; 74.74%; 52.09%; 95.86%; 24.36. Hasil statistik menunjukkan perbedaan nyata penurunan waktu perdarahan oleh karena itu dapat disimpulkan bahwa ekstrak etanol daun A. microcarpa berpengaruh terhadap waktu perdarahan pada tikus putih jantan yang diinduksi heparin.
PREVALENSI DAN POLA SENSITIVITAS Klebsiella pneumoniae DAN Escherichia coli PENGHASIL EXTENDED SPECTRUM BETALAKTAMASE DI RSPAD GATOT SOEBROTO TAHUN 2021
Authors: Yusmaini Hany , Bahar Meiskha , Harfiani Erna , Ufi Dewintera
Published: January 2025

ESBL-producing K. pneumoniae and E. coli are the Enterobacteriaceae that most commonly cause bacteriemia and nosocomial infections in the world. It is important to be aware of these bacteria to prevent an increase in infections with these resistant bacteria in hospitals. This research is a retrospective descriptive study, aiming to determine the prevalence of ESBL produced by K. Pneumoniae and E. coli and their sensitivity patterns. The data comes from clinical specimens that were examined for bacterial culture and antibiotic sensitivity tests in the Clinical Pathology Microbiology Lab in 2021. ESBL test using VITEK 2 compact tool. The results of the research were that E. coli was the most ESBL producing bacteria (50.9%) while K. pneumoniae was 20.9%. The highest prevalence of positive ESBL came from the ICU (41.4%) and the surgical ward (40.8%). Almost all rooms from which specimens were sent had a higher prevalence of positive ESBL E.coli, while for K.pneumoniae negative ESBL was higher. The most common types of positive specimens were bronchial lavage (67.4%) and wound swab (47.1%). Antibiotics that have high sensitivity to ESBL positive bacteria are Amikacin, Tigecycline and Meropenem.This research shows an increase in the prevalence of ESBL-producing K. pneumoniae and E. coli at the Gatot Soebroto Army Hospital, although it is still lower than several other national referral hospitals. Infection control, rational use of antimicrobials and prevention of transmission must continue to be pursued to reduce its prevalence.
TOXICITY TEST OF LIME PEEL EXTRACT (Citrus aurantifolia) USING THE BRINE SHRIMP LETHALITY TEST (BSLT) METHOD FOR DETECTION OF ANTI CANCER ACTIVITY
Authors: Khairunnisa Indah , Widiastuti Endang Linirin , Nurcahyani Nuning
Published: January 2025

Cancer is one of the major problems affecting the people of Indonesia and the world. Lack of public awareness for early detection causes a delay in diagnosis. One of the medicinal plants that are commonly found in Indonesia is lime (C. aurantifolia). In lime peel extract, there is essential oil composed of D-Limonene (38.94%), β-pinen (26.66%), α-terpineol (8.29%), and terpinen-4-ol (4.32%). These compounds are known to have strong effects as anti-cancer. This study used a completely randomized design (CRD) with 5 treatments and 5 repetitions, namely 0, 125, 150, 250, and 1000 ppm. The research methods used were phytochemical test, FTIR (Fourier-Transform Infrared Spectroscopy) analysis, and BSLT test. The probit value was analyzed using SPSS to obtain the LC50 value. Lime peel extract (C. aurantifolia) has an LC50 value of 331.533 ppm including the toxic category and has potential as an anti-cancer agent. Based on phytochemical and FTIR tests, lime peel (C. aurantifolia) contains alkaloid, flavonoid, and tannin compounds which are known to have antioxidant properties and can disrupt the balance of Reactive Oxygen Species (ROS) so as to trigger apoptosis of cancer cells.
AKTIVITAS ANTIBAKTERI DAN ANTIBIOFILM DARI EKSTRAK DAUN BANGUN-BANGUN (Coleus amboinicus L.) TERHADAP BAKTERI Staphylococcus aureus
Authors: Romadhonsyah Fitra , Aisha Nanda Caela Amry  , Annisa Fitria  , Arde Toga Nugraha  , Arba Pramundita Ramadani  , Nangim Khasanah
Published: January 2025

Biofilm formation by bacteria, especially the genus Staphylococcus, is a serious health problem. Various medicinal plants have been used to control the infection, but research related to the antibiofilm activity of Coleus amboinicus is still limited. Bangun-bangun leaves (C. amboinicus) are plants from the Lamiaceae family that contain secondary metabolites such as terpenoids, flavonoids, and phenolics that are thought to be responsible as antibacterial and antibiofilm. This study aims to examine the antibacterial and antibiofilm activity of C. amboinicus against S. aureus. C. amboinicus leaves were extracted using 96% ethanol. The ethanol extract was then screened for phytochemicals using Thin Layer Chromatography (TLC) using several spray reagents. Antibacterial activity was analyzed using microdilution technique to obtain the value of Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). Antibiofilm activity was analyzed using crystal violet method. The result showed that the ethanol extract of C. amboinicus leaves contained flavonoids, phenolic terpenoids, and tannins. Antibacterial assays were obtained for the MIC value of 8 mg/mL and MBC of 16 mg/mL. The ethanol extract showed biofilm inhibitory activity with an IC50 value of 2,40 mg/mL. Based on these results, C. amboinicus has potential antibacterial and antibiofilm activity to inhibit S. aureus.
In vitro activity of macrolides against Streptococcus pneumoniae and Streptococcus pyogenes in the Russian Federation: “Status praesens”
Authors: Kozlov Roman S. , Ivanchik Nataly V. , Mikotina Anna V. , Dekhnich Andrey V.
Published: January 2025

Objective.
To evaluate in vitro activity of various macrolide antibiotics against a current collection of clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes isolated from patients with community-acquired infections in different regions of the Russian Federation.

Materials and Methods.
A total of 350 clinical isolates from patients with community-acquired infections, including 200 S. pneumoniae and 150 S. pyogenes, were included in the study. To further evaluate the in vitro activity of 16-member macrolides against erythromycin-resistant isolates (MIC ≥ 0.5 mg/L), a retrospective collection of 253 erythromycin-resistant S. pneumoniae and 112 S. pyogenes isolates was tested. Susceptibility to antimicrobials was determined by broth microdilution method in accordance with the recommendations of the European Committee on Antimicrobial Susceptibility Testing (EUCAST, v.14.0).

Results.
Resistant to 14- and 15-member macrolides erythromycin, clarithromycin, and azithromycin were 41.5%, 42% and 40.5% of S. pneumoniae isolates (MIC50/MIC90 values were 0.06/128, 0.03/128, and 0.125⁄128 mg/L, respectively). MIC50/MIC90 values for spiramycin and josamycin were 0.06/128 mg/L and 25⁄32 mg/L, respectively. When the previously used 1996 French Society for Microbiology (SFM) criteria (Ch, ≤ 1 mg/L; P, > 4 mg/L) were applied, 70.5% of S. pneumoniae isolates could be considered as susceptible to spiramycin. MIC value ≥0.5 mg/L accounted for 31.5% of isolates for spiramycin and 48% for josamycin. Among the retrospective collection of erythromycin-resistant S. pneumoniae isolates, 64.0% of isolates could be considered as resistant to spiramycin using the old SFM interpretative criteria; 74.9% of isolates had spiramycin MIC ≥ 0.5 mg/L. Among the S. pyogenes isolates, 19.3%, 22%, and 26.7% were resistant to the 14- and 15-member macrolides erythromycin, clarithromycin, and azithromycin (MIC50/MIC90 0.03/1, 0.03/2, and 0.06/8 mg/L, respectively). MIC50/MIC90 values for the 16-member macrolides spiramycin and josamycin were 0.25⁄0.5 mg/L and 0.125⁄0.5 mg/L, respectively. When the 1996 SFM criteria (S – ≤ 1 mg/L; R – > 4 mg/L) were applied, 94.7% of S. pyogenes isolates could be considered as susceptible to spiramycin; MIC values ≥ 0.5 mg/L had 15.3% of isolates for spiramycin and 16.5% for josamycin.

Conclusions.
The 16-member macrolide spiramycin can retain in vitro activity against a significant proportion of S. pneumoniae and S. pyogenes isolates resistant to 14- and 15-member macrolides, which should be taken into account when choosing therapy for infections caused by these microorganisms.