bluuebunny/crossref_metadata_2025 huggingface dataset:
Modification of interest rate model based on compound poisson process and brownian motion affected by inflation rate
Authors: Himmah Faiqotul , Darti Isnani , Karim Corina
Published: June 2020

In actuarial science, interest rate model based on compound Poisson process and Brownian motion is proposed to determine actuarial present value. We used inflation rate in interest rate model to obtain the behavioural change of interest rate model under different parameters based on inflation rate data of Bank Indonesia. The interest rate model can be used to determine actuarial present value of term life insurance for discrete life annuities. To confirm the analytical result, some numerical simulations are presented.
Inventory models for short life cycle clothing products use a logistic growth model
Authors: Lukitosari V , Subriadi A P
Published: June 2020

Clothes are products that follow short-life fashion and market demand. Products with a short lifetime occur due to technological developments and/or changes in market tastes. The clothing industry is one of the industries that has a short and obsolete sales period in stages. The excess number of products that accumulate in the warehouse due to obsolescence can cause the company to get a profit that is not optimal. One strategy to increase demand for the product is to apply discounts. There are two types of discounts used, namely a single discount and multiple discounts. The demand function of inventory model is considered analogous to the logistic growth model. The results show profit is maximized to get optimal order quantity and optimal discount price.
Search for the rare decay

KL→π0νν¯

at J-PARC KOTO experiment
Authors: Shinohara S
Published: June 2020

The KOTO experiment aims to study the CP-violating rare decay

K
L

→

π
0

ν

ν
¯

at J-PARC. The analysis of the data set taken in 2016, 2017 and 2018 is reported. In order to reduce backgrounds and to improve the signal acceptance, a new barrel photon detector and a new trigger system were installed and new analysis techniques were developed. The K

L
yield was 7.1×1012. The single event sensitivity was estimated to be 6.9×10−10, which was improved by a factor of 2 compared to the data set taken in 2015. The number of background events was estimated to be 0.05 ± 0.02. Four candidate events were observed in the signal region, and their studies are on-going extensively to nd their sources.
Recent results from OKA setup at U-70 synchrotron
Authors: Obraztsov V
Published: June 2020

Several radiative decays are under study by OKA setup at U-70 synchrotron. First, the radiative decay K
+ → µ
+
νγ(K

µ2γ
) is studied on statistics of about 95K events for 25 MeV <

E
γ
*

< 150 MeV. A clear destructive interference between bremsstrahlung and structure dependent SD
− term is observed. As a result, the vector and axial-vector form factors difference is measured: F

V

−
F

A
= 0.134 ± 0.021(stat.) ± 0.027(syst.) which is 2.3 σ away from
χP T O(p
4). Moreover, the decay K
+ → π
+
π
−
π
+
γ is studied on statistics of about 450 events for 30 Mev <

E
γ
*

< 70 Mev. The total and differential branching fractions of the decay are measured. Br(K
+ → π
+
π
−
π
+
γ) = (7.1±0.4(stat.)±0.3(syst.))·10−6 to be compared with
χP T O(p
4) (6.65 ± 0.05) · 10−6. In addition, a search for an up-down photon asymmetry with respect to the hadronic system decay plane is performed.
Search for the K

L
→ π
0
γ decay in the KOTO experiment
Authors: Shimizu N
Published: June 2020

We report a preliminary result of a new search for the K

L
→ π
0
γ decay, which is forbidden by the Lorentz invariance and gauge principle. The search was carried out using the data obtained from 2016 to 2018 at the J-PARC proton beam facility using the KOTO detector. The achieved single event sensitivity was (6.9 ± 0.3stat. ± 1.5syst.) × 10−8. No signal candidate was found in the signal region and the upper limit was set to B(K

L
→ π
0
γ) < 1.7 × 10−7 at the 90% con dence level.
The RICH detector of the NA62 experiment
Authors: Brizioli F , Lollini R
Published: June 2020

The RICH detector of the NA62 experiment is one of the key detectors to achieve the muon rejection needed in the search for the

K
+

→

π
+

ν

ν
¯

decay, performed by NA62. Since BR(K
+ → µ
+
ν) is higher than BR(

K
+

→

π
+

ν

ν
¯

) by more than 9 orders of magnitude, it represents one of the most relevant background contributions. Its rejection is performed with kinematic reconstruction of the event and identification of the charged particles in the final state (π
+ against µ
+). The pion identification efficiency using the RICH detector is measured to be 83% in the momentum range between 15 and 35 GeV/c, with a misidentification probability for muons of 0.2%, while the track crossing time is measured with a resolution of 70 ps. The RICH detector is also exploited to provide trigger for charged particles with an efficiency greater than 99%.
Design and implementation of water pump control system for rice field irrigation
Authors: Arifin Rizal , Umar Rosyidin Zulkham , Malyadi Muhammad , Kurniawan Edy , Anam Khoirul , Cahya Ardhitamara Rical , Rhomadon Doni , Ega Pahlawi Muhammad
Published: June 2020

We have built an electronic instrument of water pump control system for rice field irrigation. This instrument is developed from our previous prototype with some additional features. This instrument is equipped with the keypad, GSM modem, water flow sensor, and relay as the input sources. An Arduino Mega 2560 is used as the main controller of the system. The working time of the water pump can be set using the keypad or short message service, which is received by GSM modem in the instrument. If there is no water flowing through the water pump as detected by the water flow sensor, the instrument will automatically shut down the water pump, and send the notification message to the user’s handphone. When the abnormal condition is detected on the water pump, the relay will disconnect the electricity to avoid the severe damage of the water pump. This instrument has been installed and used by the farmer in Desa Ngunut, Babadan District, Ponorogo Regency, with support from DRPM Kemenristekdikti through Program Kemitraan Masyarakat.
The design of Litopenaeus Vannamei automatic feeder
Authors: Irwan  , Iqbal Nugraha Muhammad , Anzullah Muhammad , Suci Saputri Rahmah
Published: June 2020

The province of Bangka Belitung in Indonesia has a potential of ocean fishery production of about 1, 200, 000 tons per year. On the other side, there is another oppurtunity for the government to take advantage of the mainland usage for ocean fishery. Vannamei shrimp is one of the fishery product that can be farmed on mainland. Nowadays there are numbers of Vannamei shrimp’s company in Bangka Belitung. Feeding process of Vannamei shrimp is one problem in this business. The food residual can cause about 60% of organic waste. To anticipate this problem, an automatic feeder has been developed, even though they are not optimized yet. The propose of this study was to design a new method of automatic feeder which can spread the pellets from 0 to required distance in meters and of a food transporter that can flow pellets properly. The machine has been designed to be operated using android-based system. This brings the ease of use to control and monitor the feeding process. The result shows that the automatic feeder can achieve 15 meter in maximum distance of food throwing. Spreading the food can be from 0 up to 15 meter based on the speed controlling of throwing (0 to 700 rpm). The auto-feeder can also be monitored using android system such as the volume of the food, and on/off the system manually.
Plasma intensification in 2 MHz RF glow discharge in carbon film plasma sputtering deposition by means of a hollow cathode
Authors: Santjojo Dionysius J.D.H. , Pambudi Dwi R.S. , Masruroh
Published: June 2020

A hollow cathode has been one of the methods to intensify the plasma in the etching or ashing process. This work examined a number of technologies in the intensification of a 2 MHz RF glow discharge plasma to deposit carbon film by means of the hollow cathode. Three types of the cathode configurations, which were cylindrical, rectangular and a cylindrical-rectangular combination, were tested to get an optimum condition for the carbon deposition. Both carbon target and substrate were fixed inside the hollow cathode. The plasma was characterized by means of optical emission spectroscopy (OES) at the range of 200 nm – 1000 nm. The results showed that the combination where the rectangular hollow was placed inside the cylindrical one, produced the most intense glow. Ion density and electron temperature in the plasma were determined by a calculation based on the atomic data related to the specific electronic transitions of the ions. The density of ions was very high in the centre area of the rectangular hollow producing complex reactions. On the other hand, the high density of the ions decreases the electron temperature. The energy of the ions was difficult to be predicted since the spectrum showed the existence of a large number of ion states. Observations on the resulted deposit on the surface of quartz substrate suggest that the intensification needs to be further investigated related to the effectiveness of sputtering and deposition process.
Implementation of convolutional neural networks to determine lightning location
Authors: Sashiomarda J A , Aji A S , Handoko D
Published: June 2020

Lightning produces not only electromagnetic signals but also thunder sound signal. A new method was proposed to determine lightning location by measure time of arrival (TOA) of lightning electromagnetic signals and thunder sound signal to get lightning distance using Convolutional Neural Network (CNN). These signals were caught by using a set of cell phones. These cell phones collect three main data i.e. the TOA of lightning electromagnetic signals, the TOA thunder sound signal, and the coordinates obtained from Global Positioning System (GPS). In this study, CNN determines thunder sound signal pattern which is recorded by certain cell phone. More than one hundred samples of thunder sound signals were used as data set. Whole data set divide into three categories i.e. training data, validation data, and testing data. The model runs few hours to train the network and then produce a confusion matrix. The matrix consists of several column represents a set of samples that previously predicted by their labels and several rows represents actual labels. The labels are thunder sound and the other sound. After the model created, it is exported to the cell phone so that every time cell phone record a sound signal, the model will predict whether the thunder sound or not. When the model predicts the sound as thunder sound, the cell phones save the exact occurrence time. This determination is very important when the cell phone is going to measure lightning distance between lightning location and cell phone location.
Analysis of magnetic resonance image quality using an in-house phantom: Gamma knife application
Authors: Fauzia A R , Setiadi A R , Pawiro S A
Published: June 2020

Magnetic Resonance Imaging (MRI) is increasingly used for purposes of radiosurgery and radiotherapy planning. This imaging modality can explore the physical properties of tissue with great details, especially for the brain. However, the geometric distortion is reasonably occurred and can make significant differences in certain MR application such as, localization in Gamma Knife Radiosurgery. Therefore, the geometric distortion measurement and correction should be applied. In this study, an in-house phantom was developed to measure not only geometric distortion, but also uniformity and high contrast spatial resolution of MR image. The phantom attached to Leksell stereotactic frame was scanned using 1.5T MRI GE. T1-Bravo and T2-Fiesta scan protocol were applied. Standard MRI phantom, Magphan SMR100, was used as data comparison. The result shows that geometric distortion could not be found either in Magphan SMR 100 or in-house phantom images. PIU of the in-house phantom image generated by T1-Bravo and T2-Fiesta scan protocol was around of 79.57% and 56.39%, respectively. Furthermore, the high contrast spatial resolution of the in-house phantom images was 1.0 lp/cm lower compared to Magphan SMR100 phantom images. For this study, it was concluded that the in-house phantom could be employed to analyze MR image quality, yet still needs some improvements, especially for uniformity module.
Integration of LAPAN’s remote sensing ground station control and monitoring system application
Authors: Syahputra Nasution Ali , Gunawan Hidayat
Published: June 2020

The National Institute of Aeronautics and Space (LAPAN) - Remote Sensing has developed different website-based application systems. The application system is used to control and monitor several series of ground station processes ranging from acquisition, recording, processing, storage, to cataloguing data and remote sensing satellite products. At present these applications are still working separately which are built from various platforms both operating systems, programming, databases, infrastructure and architecture. Therefore, an application system integration solution is needed in order to facilitate and speed up ground station operators to control and monitor the processes that take place and obtain useful and valid information for decision making. The design of this system integration application is done by preparing materials and defining layouts, coding Hypertext Pre-processor (PHP), testing designs, granting domains, and providing hosting. The User Interface (UI) uses a bootstrap framework to display responsive results for each screen size.
Development of ECG sensor using arduino uno and e-health sensor platform: mood detection from heartbeat
Authors: Dioren Rumpa Lantana , Suluh Sallolo , Hendrika Ramopoly Irene , Jefriyanto Wilson
Published: June 2020

Many researcher said that emotion or mood can be detected from physiological changes like the heartbeat. In order to measure human heart activity, we were using tools like Electrocardiograph. The changes on human emotion or mood affect physiology. This paper is part of our research that talked about Analysis of Mood State from Heart Signal during Playing Flappy Bird. In this paper, we will explain how we design ECG tools that could measure or detect the human heartbeat especially that affect by mood changes. E-Health Sensor Platform v2.0 and Arduino Uno were used to build this system. E-Health Sensor Platform v2.0 contains several sensors that can measure the biological state of humans such as heart rate, breathing, skin conductance and many others. This device can operate when connected with Arduino Uno as a microcontroller. Arduino uno role as a liaison between the Platform and the PC via a serial port. We were using C programming languange on Arduino Uno. 100 Hz were sett in programming code so we can read all data from ECG sensor clearly. To visualize the heartbeat signals we were using KSTPlot. This system has successfully read the heart signals of 20 participants. Although there is signal noise but it does not affect the data. The noise can also be removed with a filter.In our next study, the raw data will be analyzed using the HRV method, but this will be discussed in another paper.
Surface temperature changes of the crater of Agung Volcano from Landsat-8 TIRS during 2017-2018 eruption
Authors: Suwarsono  , Triyono D , Khomarudin MR , Rokhmatuloh
Published: June 2020

This paper described the application of Landsat-8 TIRS (Thermal Infra Red Sensor) to analyze the surface temperature changes of the crater region of Agung volcano during early of 2013 until late of 2019. Agung volcano is an active stratovolcano located in Bali island. We processed the brightness temperature from channel-10 of Landsat-8 TIRS during early of 2013 – late of 2019 and analyzed the changes. The results of this research showed that the eruptions that occurred during 2017 - 2018 have indicated highly increasing in the surface temperature of the crater region. The surface temperature changes of the crater region, which can be detected from Landsat-8 TIRS data, can be used as a precursor of an eruption.
Detection of mercury ions using unmodified silver nanoparticles as colorimetric indicator
Authors: Handayani W , Pratiwi N I , Imawan C
Published: June 2020

Detection of the heavy metal presence in an environment requires a rapid and facile method. Silver nanoparticles (AgNPs) can be develop as colorimetric indicator related to their unique characteristics of its LPSR properties. In this research, biosynthetically AgNPs using Diospyros discolor leaf extract used as a colorimetric indicator for detecting Hg2+ ions. The solution color changes that occur when detecting the analyte was observed. The characterization was performed using a UV-Vis spectrophotometer to study changes in the LSPR spectrum of silver nanoparticles when detecting the presence of Hg2+ ions. In addition, the image analysis from Transmission Electron Microscope (TEM) was carried out to determine the shape and size of the AgNPs. The results obtained indicate that there was a tendency for the solution color change from brown to light-brown when AgNPs interact with Hg2+ ions at 500-1000 mg. L−1. This result showed that without modification the biosynthesized AgNPs tend to be selective and sensitive to the presence of Hg2+ ions.
New insight of the implication blood pressure detection differences using aneroid sphygmomanometer and digital blood pressure on medical examination
Authors: Novitasari  , Pratiwi N G , Hidayat S W , Ardiatna W , Hidayat A R , Supono I
Published: June 2020

The quality of medical devices is an important thing to establish the anamnesis, diagnosis and also treatment of patient. Arterial pressure measurement as one of the first indicators in the Hypertension Management Guidelines requires the accuracy as well as their function. Error in the detection of blood pressure should not occur during measurement because the errors will also make failure in determining the diagnosis and therapy for hypertensive patient, related on their hypertensive classification. Clinicians requires accurate medical measurement in order to monitor patients, diagnose diseases and deliver treatments. The failure of detection will certainly have diverse effects. Preliminary studies have shown that differences in results that are generated by two types of blood pressure devices, aneroid sphygmomanometers and digital blood pressure. The differences between both devices are 2-11, 6 mmHg for Systolic and 0.8 - 10.3 mmHg for diastolic. This differences led a new insight to the accuracy of blood pressure devices that are widely used in medical circles and the critical value of the accuracy of the sphygmomanometer can be the basis for determining clinical blood pressure classification. Therefore, it is necessary for medical staff to get information about the accuracy of blood pressure devices and its critical parameters in determining blood pressure, it is also necessary for a regulation on a blood pressure classification based on the type and level of accuracy of measuring instruments.
Long-term change in characteristics of cloud vertical structures in Padang from radiosonde observations
Authors: Lismalini  , Marzuki
Published: June 2020

The characteristics of clouds continue to change with climate change, including changes in cloud-base heigh (CBH), cloud tops (CT) and the number of layers of clouds. This work investigates cloud vertical structures in Padang using long-term observations of radiosondes (1988-2019). Height of CBH identified based on the relative humidity threshold. of 84% following the method proposed by several previous studies. The vertical distribution of cloud tops, cloud base has increased over time in all cloud layers, but cloud thickness has decreased. The most commonly observed cloud layer in Padang is one layer cloud (58.87%), followed by two layer cloud (31.12%). The cloud with more layer is also observed but the number is relatively small (10%).
ECG calibration signal database construction based on IEC 60601-2-25 using MATLAB
Authors: Hidayat S W , Ardiatna W , Pratiwi N G , Novitasari  , Supono I , Hidayat A R
Published: June 2020

ECG machines should be calibrated and tested to assure their accuracy. IEC 60601-2-25 standard described signals for calibrating ECG amplitudes and frequencies. The problem was this standard does not clearly describe the formulas of the calibration signals nor the complete database of these signals. The aim of this study was to get a database of ECG calibration signals for testing based on IEC 60601-2-25 standard clause 201.12.1.101. Data were constructed with a series of sinus function in Matlab software to simulate P, Q, R, S, and T segments. The data were visually and statistically compared with the data from commercial CTS database. Data were constructed for 3 different lead of 12 ECG calibration data. Four ECG calibration data with elevation or depletion ST segment were excluded from this study. This study demonstrated that these ECG calibration signals were slightly visually different and statically had differences in some of S wave and most of T wave. This data can be used by designers or manufactures, but for the testing laboratory is recommended using a commercial product.
Metal bioavailability in northern low-salinity water: Case study of lakes in the Kola region, Russia
Authors: Moiseenko T I , Gashkina N A , Dinu M I
Published: June 2020

This paper presents metal speciation calculations that are based on mathematical modelling of chemical reactions in natural waters. Metal concentrations (Hg, Cd, Pb, Ni, Cu, Al, Sr) were determined, and their speciation in water were calculated for 22 water areas in the Kola region. Meanwhile, the accumulation of metals in fish organs and tissues was studied (e.g. whitefish). The biogeochemical activity of metals determines the proportions of labile and non-labile speciation in water. In the distribution zones of non-ferrous industry effluents, metal aqua-ions prevail; during the distribution, the proportions change in accordance with the metal activity. The bioavailability of metal speciation is estimated depending on aqueous geochemical conditions and, accordingly, the speciation of metals (in situ), based on the original studies of the lakes of the Kola region in northern Russia. The connection among the metal contents in fish and water has been identified using multidimensional scaling and redundancy analysis techniques. Using the example of natural conditions in northern low-salinity freshwaters, it is demonstrated that labile Cd, Pb, Ni, Cu, Al, and Sr are the species most bioavailable and able to penetrate fish; meanwhile, the organic complexes of Hg, Pb, and Al have a greater affinity to accumulation in the gills. This study demonstrates the need to correct the approved water quality standards in Russia, taking into account the high bioavailability of metals in northern low-salinity waters.
Architecture for sharing
Authors: Rahman A , Lompoliuw L
Published: June 2020

Architecture bureaus tend to sterilize their office from public activities. They tried to stay untouched from common people, keeping their ‘corporate secrets’ away. This situation creates a closed-environment office from the surroundings and less contribution that might bring better change. Andyrahman’s Co-Sharing Office tries to break the boundaries, standing as an oasis between its surrounding, community, and other architectural bureaus. It provides an opened communal space for experts to students, hamlets, communities, and even craftsmen to share their knowledge and experiences. Bricks as the main material used in this building also revive the spirit of Nusantara Architecture, a contextual architecture in accordance with the culture and values of Indonesia as a Nusantara. While its own name stands for ‘Consciousness of Sharing’, it really does provide a place for everyone to share their interests, and giving a significant impact in many possible forms.
Impacts of partial greenery facade to indoor light illuminance and thermal
Authors: Kristanto L , Widigdo W , Nata S H , Jusuf S K
Published: June 2020

This paper reported a research of facade greenery impacts to indoor light and thermal using two models. The first was without greenery as base case, and the other was with climbing ivy plants as greenery facade. Besides the indoor light illuminance, the air temperature and relative humidity (RH) were measured for thermal data. The experiments were done for west orientation, on dry season in March to April 2018 and for south orientation, on dry season on 14 to 22 November 2018. The result for west orientation, the facade with vegetation reduced more (31.18 to 51.71) % sunlight compared to facade without vegetation. The highest reduction was on 4.30 pm to 6.00 pm. For south orientation, the facade with vegetation reduced more (28.4 to 54.87) % sunlight compared to facade without vegetation. The highest reduction was on 05.15 am in the morning and 4.30 pm to 5.00 pm in the afternoon. Meanwhile, the indoor thermal impact was unsignificant, reduction for air temperature only (0.5 to 1) °C, and only 1 % reduction for the RH. For greenery facades, vegetation impacts to light were determined by its orientation, depth and surface area it covered, while for thermal impact, the bigger LAI was the better.
Empathic urban functions on Malioboro Street in Yogyakarta City, Indonesia
Authors: Saraswati T
Published: June 2020

Malioboro Street in Yogyakarta City, Indonesia, is named as one of the most popular tourism destinations for both domestic and foreign tourists. People even said that they were not yet visited Yogyakarta if they did not visit Malioboro Street. It is the main shopping street in Yogyakarta with its pedestrian ways or sidewalks occupied by street vendors. Yet, this is the attraction of Malioboro Street, bazaar on pedestrian ways. While in other places in the world the function of the pedestrian way just for pedestrians only, in Yogyakarta the street vendors could freely occupy pedestrian ways for the commercial matter. It was likely that there were dynamic, empathic urban functions to this street. With this condition, the question of this study is: What kind of empathic urban functions already executed and implemented to this street? The conclusion was that there were some mutual empathic urban functions implemented between the rulers of Yogyakarta City and the people.
Buk: An inornate folksy construction in creating cultural space
Authors: Yusran Y A , Santoso D K
Published: June 2020

Indonesian society has its unique tradition reflected on how architectural elements are formed according to their own culture. One interesting phenomenon found in Malangsuko Hamlet, Malang Regency, Indonesia is a construction of a low wall called Buk. The buk is a simple construction shaped as a barrier on the sides of the bridge in front of the house that sized to the proportion of human sitting and is usually joined with the house’s fence. This construction eventually used as a place for various activities, such as sitting, chatting with neighbours, or gathering. Almost all houses in this hamlet own the buk. This paper tries to describe this phenomenon descriptively to get a more comprehensive understanding through the point of view of place attachment. This study provides another perspective in considering an inornate construction around society which built folksy by the locals. The result of this study shows that the buk interpreted as a place and has an emotional significance to the culture and its people. The buk has produced the social interaction and harmony between neighbours and be perceived into a cultural space by the community because of the activities therein and interactions formed between each other.
Determine the effect of gamma irradiation towards the growth of two local garlic genotypes
Authors: Pangestuti P W , Sudarsono S , Dinarti D
Published: June 2020

Garlic is a diploid plant that is propagated clonal or vegetatively so that the variability is low. Garlic breeding is limited to the selection of genetic varieties. Genetic diversity in garlic can be increased through mutation breeding. The study used Randomized Complete Block Design [RCBD] with the first factor being the two levels of genotypes [Tawangmangu Baru and Lumbu Kuning] and the second-factor is gamma-ray irradiation dose consisting of 7 level doses [0,1, 2, 3, 4, 6,8, and 10 Gy]. 14 treatments were groups 4 times and each experimental unit was planted 20 cloves. The cloves were irradiated according to the dosage of gamma rays in PAIR BATAN. The results showed there was a difference in the growth response of each genotype to gamma rays irradiation treatment. The greater the gamma rays irradiation applied the more it suppresses the growth of plant height, plant weight, bulb diameter, bulbil formation and decreases the living percentage of two local garlic genotypes. Gamma rays irradiation dose up to 2 Gy could increase bulb diameter in the 2 local garlic genotypes. Lumbu Kuning was significantly better growth response than Tawangmangu Baru at the same irradiation dose. The radiosensitivity of garlic genotype to gamma rays irradiation was different. Tawangmangu Baru was more sensitive than Lumbu Kuning. LD50 genotype Tawangmangu Baru was obtained at a dose of 7.5 Gy, LD50 Lumbu Kuning at a dose of 10 Gy.
Toxicity of Bacillus thuringiensis Berl. KJ3P1 and DLM isolates towards pest of oil palm Oryctes rhinoceros [Coleoptera: Scarabaeidae]
Authors: Pujiastuti Y , Sandi S , Arsi A , Sulistyani D P
Published: June 2020

Oil palm plants are industrial plants that generate foreign exchange for Indonesia. Some obstacles are leading to production decrease. One of the important pests is Oryctes rhinoceros [Coleoptera: Scarabaeidae]. Both larval and imago stadia attack oil-palm in immature plants [IP] and mature plants [MP]. The method of controlling Oryctes often use chemical insecticides, in which continuously applications will cause residues in the environment and mortality of non-target insects. Therefore it is necessary to find an environmentally friendly control method that is easy, inexpensive and safe for the environment. The use of entomopathogenic bacteria Bacillus thuringiensis is an alternative. The study was aimed to study the toxicity of two B. thuringiensis isolates from the collection of Plant Protection Department, Faculty of Agriculture, Sriwijaya University [KJ3P1 and DLM isolate codes] on mortality of 3rd instar Oryctes larvae. Experiments were conducted at the Entomological Laboratory, Department of Plant Protection, Faculty of Agriculture, Sriwijaya University from March until May 2019. Bioinsecticide-based B. thuringiensis was made with 2 types of growth media, namely: 1] cow’s bio-urine enriched with 5% molasses, and 2]. Rice washing water enriched with 5% molasses. Treatments were included: 1] DLM5 isolate, 2] KJ3P1 isolate, 3] commercial B. thuringiensis and 4]. without treatment [as control]. The test insects used were 25 individuals of 1st instar Oryctes larvae in each treatment. The results showed KJ3PI isolate that propagated in bio-urine media showed the highest production of B. thuringiensis [5.69 x 106 spores/ml], the highest mortality [76% ] and the lowest LT50 value [5.28 days] as well. The use of agricultural and livestock waste as a medium to multiply B. thuringiensis bacteria may produce high cell and spore production and can be used as bioinsecticides to control O. rhinoceros.
Viability of Lactobacillus plantarum and Lactobacillus pentosus isolated from solid waste of soy milk as candidate probiotic for poultry
Authors: Anggraeni S D , Husmaini H , Sabrina S , Zulkarnain Z , Rossi E
Published: June 2020

This study was aimed to determine the viability of Lactobacillus plantarum and Lactobacillus pentosus isolated from soy milk waste as a candidate for poultry probiotics in vitro. This research was designed in the form of a laboratory experiment descriptively. This study was conducted in several stages, viability test at 37°C and 42°C, viability test at pH 2 and 7, viability test for 0.3% and 0.5% bile salts, viability test of adhesion [hydrophobicity] and antimicrobial activity against pathogenic bacteria [Escherichia coli 0157, Staphylococcus aureusATCC-25293 and Salmonella sp]. The result showed that Lactobacillus plantarum and Lactobacillus pentosus survived and grew at 37°C and 42°C [observation time at 30 and 60 minutes], pH 2, and resistant for 0.3% and 0.5% bile salts. Both bacteria also could inhibit the growth of pathogenic bacteria [active category], which produced clear zones with diameters <30mm. Hydrophobicity test used stainless still found that both bacteria had high hydrophobicity [<40%], 82.82% and 82.71%]. This study concluded that both of Lactobacillus plantarum and Lactobacillus pentosus isolated from soy milk waste have potential as a probiotic for poultry.
The effect of a parallel free surface upon a submerged shallow synthetic jet
Authors: Kumar Abhay , Saha Arun K , Panigrahi Pradipta K , Karn Ashish
Published: June 2020

The interaction of a submerged shallow synthetic jet with a parallel free surface has gathered substantial interest, owing to its relevance to the operation of marine vehicles viz. ships that move close to the water surface. However, despite exhaustive research on the perturbation on a free surface, very few studies have experimentally investigated the effect of unconfined water surface height on the evolution and propagation of a submerged synthetic jet. This study experimentally investigates a synthetic jet submerged in a quiescent flow at shallow depths ejecting parallel to the free surface, through qualitative analysis and quantitative measurements. The qualitative study includes the visualization of the flow using plane laser induced fluorescence (PLIF) technique, whereas the velocity measurements are carried out by a five-beam laser Doppler velocimetry (LDV) probe. The primary objective of these analysis and measurements is to gain a physical insight into the characteristics of vortex ring in a synthetic jet ejected from a fixed orifice at different water depths and at varying Reynolds number. Our studies indicate that the behavior of the vortex rings drastically changes as the depth of the jet crosses a certain threshold. Although no significant change in the path of synthetic jet is observed beyond a threshold depth in our experiments, the jet trajectory shows an interesting dependence on the Reynolds number based on circulation for shallow water depths. It has been found that at the shallow depths, the vortex ring drifts upwards and interacts with the free surface at lower Reynolds number, whereas for larger Reynolds number, the vortex ring rebounds near the free surface and moves downward. Based on our observations, it can be concluded that the phenomenon of upward/downward flection of vortex rings depends both upon its circulation and ejection depth.
Effect of milling time on XRD phases and microstructure of a novel Al67Cu20Fe10B3 quasicrystalline alloy
Authors: Amini Meysam , Rahimipour Mohammad Reza , Tayebifard Seyed Ali , Palizdar Yahya
Published: June 2020

The quasicrystalline materials represent a new materials group with definite crystallite structural characteristics, in which the AlCuFe(B) quasicrystalline alloys have been widely studied owing to its various technological advantages such as easily accessible in nature, thermal stability, affordability as well as not having toxic constituent elements. Although these materials can be achieved by different procedures, the synthesis of more extensive amounts of AlCuFeB quasicrystalline single-phase powders is more complicated. In this study, the Al67Cu20Fe10B3 quasicrystalline alloys were synthesized through the mechanical alloying process and afterward consolidated to the bulk specimens by cold isostatic pressing (CIP) technique. The structural and microstructural evolutions, as well as the morphology of as-milled powders and phase transformations, were studied during the ball milling process using field-emission scanning electron microscopy (FESEM) and x-ray diffractometry (XRD), while the thermal behavior was investigated using differential thermal analysis (DTA). The most fascinated result revealed that the stable AlCuFeB single quasicrystalline phase could be directly synthesized in short milling times (around ∼4 h) by a high-energy planetary ball milling. It was appreciated that the icosahedral phase is stable up to 300 °C, which is misplaced stability at superior temperatures and transforms into crystalline phases. The microhardness of consolidated ball-milled powders at various milling times was determined and it was figured out that the icosahedral phase has an extreme microhardness as much as 10.73 GPa.
First-principles-derived effective mass approximation for the improved description of quantum nanostructures
Authors: Yeo Hyeonwoo , Lee Jun Seong , Khan Muhammad Ejaz , Kim Hyo Seok , Jeon Duk Young , Kim Yong-Hoon
Published: June 2020

The effective mass approximation (EMA) could be an efficient method for the computational study of semiconductor nanostructures with sizes too large to be handled by first-principles calculations, but the scheme to accurately and reliably introduce EMA parameters for given nanostructures remains to be devised. Herein, we report on an EMA approach based on first-principles-derived data, which enables accurate predictions of the optoelectronic properties of quantum nanostructures. For the CdS/ZnS core/shell quantum rods, for which we recently reported its experimental synthesis, we first carry out density functional theory (DFT) calculations for an infinite nanowire to obtain the nanoscopic dielectric constant, effective mass, and Kohn-Sham potential. The DFT-derived data are then transferred to the finite nanorod cases to set up the EMA equations, from which we estimate the photoluminescence (PL) characteristics. Compared with the corresponding method based on bulk EMA parameters and abrupt potential, we confirm that our EMA approach more accurately describes the PL properties of nanorods. We find that, in agreement with the experimentally observed trends, the optical gap of nanorods is roughly determined by the nanorod diameter and the PL intensity is reduced with increasing the nanorod length. The developed methodology is additionally applied to CdSe nanoplatelets, where reliable experimental data became recently available. Here, we again obtain excellent agreements between calculated and measured optical gap values, confirming the generality of our approach. It is finally shown that the abrupt confinement potential approximation most adversely affects the accuracy of EMA simulations.
Graphitic carbon nitride quantum dots (g-C3N4) to improve photovoltaic performance of polymer solar cell by combining Förster resonance energy transfer (FRET) and morphological effects
Authors: Pareek Saurabh , Waheed Sobia , Rana Aniket , Sharma Punit , Karak Supravat
Published: June 2020

In this study, multifunctionality of graphitic carbon nitride quantum dots (g-C3N4 QDs) have been explored as a photovoltaic booster for polymer solar cell. Facile synthesis method of g-C3N4 QDs using organic solvent like o-dichlorobenzene which is commonly used for cell fabrication, has been demonstrated. Photovoltaic effect formation and various effects of QDs on energy transfer, carrier transport and nanoscale film morphology of the devices have been investigated thoroughly by incorporating g-C3N4 QDs as a third component into a well-established material combination of P3HT: PC71BM blend films. While systematic variation of device performances was observed with varying concentration of QDs, at an optimal concentration of 2%, almost 40% performance improvement was achieved compared to the pristine devices. The g-C3N4 QDs were found to assist Förster resonance energy transfer (FRET) between the QDs and host polymer, improving overall energy harvesting capability of the devices. The emission spectra of g-C3N4 QDs (λ
Ems = 400–550) and absorption spectra of P3HT (λ
Abs = 400–600) were found to have overlapping features which enabled the QDs to transfer ultraviolet region photon energy to P3HT. The g-C3N4 QDs were also found to be favorable for maintaining nanoscale phase segregation of the active layer with improved crystallinity which is crucial for efficient exciton dissociation and faster charge extraction. The enhanced power conversion efficiency thus attributed to the combined consequences of improved morphology and FRET effect. This study opens new prospects for developing high-efficiency solution processable photovoltaic devices using g-C3N4 QDs as the third component of the active layer.
HEXIM1 controls P-TEFb processing and regulates drug sensitivity in triple-negative breast cancer
Authors: Shao Hengyi , Zhu Qingwei , Lu Huasong , Chang Amanda , Gao Carol , Zhou Qiang , Luo Kunxin
Published: June 2020

HEXIM1 is often down-regulated in human triple-negative breast cancer (TNBC), and these cancer cells are highly sensitive to Hsp90 inhibitors. However, the mechanistic link between the two has not been determined. Our study provides a mechanistic explanation for the increased sensitivity of TNBC to Hsp90 inhibition.
Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation
Authors: Baumhardt Jordan M. , Walker Janek S. , Lee Yoonji , Shakya Binita , Brautigam Chad A. , Lapalombella Rosa , Grishin Nick , Chook Yuh Min
Published: June 2020

Structural and biophysical studies show that CRM1(E571K) binds differently to a small subset of nuclear export signals (NESs). NESs of Mek1, RPS2, and 4E-T bind CRM1(E571K) >10-fold differently, but only 4E-TNES is accessible in the full-length protein. 4E-T is mislocalized to the nucleus in HEK 293 and patient cells carrying CRM1(E571K).
Occupational Exposure to Particulate Matter and Volatile Organic Compounds in Two Indoor Cannabis Production Facilities
Authors: Silvey Brynne , Seto Edmund , Gipe Alexander , Ghodsian Niloufar , Simpson Christopher D
Published: June 2020

Legal commercial cultivation and processing of cannabis is a rapidly growing industry in multiple countries. However, to date little effort has been made to characterize and identify the various occupational hazards that workers may be facing in the cannabis production industry, including airborne contaminants that may affect the human respiratory system. In the current study, we quantified occupational exposures to particulate matter (PM) and volatile organic compounds (VOCs) in various task zones of two indoor cannabis facilities in Washington State. Full-shift (8-h) area measurements of PM and VOCs were collected in each task zone. Measurement devices were placed near the employee’s work area in order to attempt to estimate the personal exposure to the contaminants. In each task zone we measured particle number concentration, particle mass concentration (PMC), cumulative size distribution of the particles, and total terpene mass concentrations. The mean PMCs were greater in task zones that required the employees to manipulate the cannabis plants and materials. The arithmetic mean PMC for the trim task was 60 µg m−3, preroll task was 45 µg m−3, grow task was 42 µg m−3, and the referent office area was 27 µg m−3. When comparing each task zone PMC to the office referent PMC, the trim task, and the preroll task were significantly higher than the referent group (P-values both <0.05). The arithmetic mean terpene mass concentration for the trim task was 36 mg m−3, preroll task was 9.9 mg m−3, grow task was 15 mg m−3, and for the office referent space was 4.9 mg m−3. Compared with the office space, only the trim task area had significantly elevated terpene mass concentrations (P-value <0.01). We observed a weak but statistically significant correlation between PMC and total terpene mass concentrations (rho = 0.42, P < 0.02). Overall, we observed that exposures to respiratory hazards were highest in task zones where cannabis plants and material were manipulated by workers, including the trim, preroll, and the grow task areas. These observations can help inform the employer of the task zones where exposure to respiratory hazards are the highest, and where it may be beneficial to deploy control measures to reduce worker exposures.
Gender Differences in Grant Submissions across Science and Engineering Fields at the NSF
Authors: RissleR Leslie J , Hale Katherine L , Joffe Nina R , Caruso Nicholas M
Published: June 2020

There has been great growth in women's participation in the US academic doctoral workforce, but underrepresentation remains in all science and engineering fields, especially at high academic ranks. We obtained estimates of the numbers of professorial women and men in fields likely to seek funding from the National Science Foundation and aligned those numbers with each of six research directorates to investigate temporal trends in submission patterns. We found that women are as likely to be funded as men, but the percentage of women submitting proposals was less than expected in every field but engineering. Women are as likely as men to be employed at the most research active institutions, but women are less likely than men to self-report research as their primary work activity in almost all fields but engineering. This work imbalance ultimately limits the diversity of basic science research ideas in science and engineering.
Epigenetic modulation combined with PD-1/PD-L1 blockade enhances immunotherapy based on MAGE-A11 antigen-specific CD8+T cells against esophageal carcinoma
Authors: Wu Yunyan , Sang Meixiang , Liu Fei , Zhang Jiandong , Li Weijing , Li Zhenhua , Gu Lina , Zheng Yang , Li Juan , Shan Baoen
Published: June 2020

Cancer testis antigens (CTAs) are promising targets for T cell-based immunotherapy and studies have shown that certain CT genes are epigenetically depressed in cancer cells through DNA demethylation. Melanoma-associated antigen A11 (MAGE-A11) is a CTA that is frequently expressed in esophageal cancer and is correlated with a poor esophageal cancer prognosis. Consequently, MAGE-A11 is a potential immunotherapy target. In this study, we evaluated MAGE-A11 expression in esophageal cancer cells and found that it was downregulated in several tumor cell lines, which restricted the effect of immunotherapy. Additionally, the specific recognition and lytic potential of cytotoxic T lymphocytes (CTLs) derived from the MAGE-A11 was determined. Specific CTLs could kill esophageal cancer cells expressing MAGE-A11 but rarely lysed MAGE-A11-negative tumor cells. Therefore, induction of MAGE-A11 expression is critical for CTLs recognition and lysis of esophageal cancer cells. Treatment with the DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine increased MAGE-A11 expression in esophageal cancer cells and subsequently enhanced the cytotoxicity of MAGE-A11-specific CD8+T cells against cancer cell lines. Furthermore, we found that PD-L1 expression in esophageal cancer cells affected the antitumor function of CTLs. programmed death-1 (PD-1)/PD-L1 blockade could increase the specific CTL-induced lysis of HLA-A2+/MAGE-A11+ tumor cell lines treated with 5-aza-2′-deoxycytidine. These findings indicate that the treatment of tumor cells with the DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine augments MAGE-A11 expression in esophageal cancer cells. The combination of epigenetic modulation by 5-aza-2′-deoxycytidine and PD-1/PD-L1 blockade may be useful for T cell-based immunotherapy against esophageal cancer.