bluuebunny/crossref_metadata_2025 huggingface dataset:
Le portrait narratif : de l’entretien oral à l’autoportrait écrit
Authors: Hong Jing
Published: October 2023

L’article procède à la comparaison des deux versions – orale et écrite – d’un témoignage d’adolescente, Jeanne, sur la précarité de la vie de sa famille. Le témoignage de la jeune fille a d’abord été enregistré dans le cadre de l’émission radiophonique produite par Sonia Kronlund, Les pieds sur terre (France Culture) ; puis il a fait l’objet d’un livre dont le titre est Cœur gros, ventre vide, le sous-titre récit, les autrices, Jeanne et la journaliste Farida Taher (2013), et l’éditeur, Robert Laffont. La narrativité est à l’œuvre dans les deux versions : la jeune fille « raconte » sa vie. Mais si la version orale et radiophonique s’apparente à un « récit exemplaire » (Suleiman, 1983), la version livresque tient davantage du « portrait de presse » dans ses « scansions individuelles du social » (Wrona, 2012). La comparaison des deux versions engage une discussion sur ces genres de discours et sur leurs spécificités narratives. Quelles relations entretiennent le récit exemplaire et le portrait narratif avec la fonction testimoniale qui leur est commune ?
Medical Data Analytics
Authors: Keerthika K. , Kannan M. , Khang Alex
Published: October 2023

Foreseeing trends and facilitating better decision-making, data analytics is a diverse field. Data analytics uses mathematics, computer science, and statistics to make use of the data beyond analytics. Data are used in a number of industries, including social security, commercial marketing, advertising, fraud detection, transportation, education, and internet site search, for prediction and framing techniques. With a focus on the healthcare industry, the chapter starts by presenting data analytics and its several subtypes, including descriptive, diagnostic, predictive, and viewpoint analytics. Furthermore, a description of the fundamental abilities such as statistical, mathematical, and database access that are necessary to manage a wealth of healthcare data is offered. Patient preventative care, patient management, public health management, medication development, and healthcare fraud detection are among the applications of data analytics that are covered in the part examining how to improve the standard of care in the healthcare industry.
Early Diagnosis of Lung Nodules With Deep Neural Networks
Authors: Kashyap Seema , Shukla Arvind , Naim Iram
Published: October 2023

Cancer stands out as a disease with a high mortality rate around the world, and some types of cancer, namely lung, skin, nervous system, breast, colorectal, prostate area, and blood-related cancers, are more threatening. The final goal of the chapter is to help improve early cancer diagnosis and come up with possible ways to fight the terrible effects of these deadly diseases. Lung cancer is a very dangerous disease that can grow quickly and spread to other parts of the body through a process called dissemination. It is essential to detect and precisely diagnose cancerous lung nodules to begin therapy as soon as possible. CT scan pictures are being sorted by using machine learning, especially advanced CNN models like vgg16 ang ResNet50v2. There are a variety of obstacles, such as abnormalities in nodule patterns, shapes, and sizes, as well as contextual complications. The goal of this study is to improve precision by using preliminary processing, methods like ADASYN, and solving class imbalance.
AI-Aided Data Analytics Tools and Applications for the Healthcare Sector
Authors: Khang Alex , Abdullayev Vugar , Alyar Abuzarova Vusala , Khalilov Matlab , Murad Bagirli
Published: October 2023

Modern businesses have come to rely heavily on data analytics because it offers insightful information about consumer behavior, operational effectiveness, and financial performance. Organizations employ a variety of data analytics technologies, including Tableau, Excel, Python, and R, to analyze enormous volumes of data and derive actionable insights. These tools assist in gathering, purifying, processing, analyzing, and visualizing data to find patterns and trends. Numerous sectors, including marketing, finance, healthcare, manufacturing, and retail, can benefit from data analytics. Businesses may make wise decisions, improve productivity, cut expenses, and gain a competitive edge by utilizing data analytics tools and apps not only for healthcare sector but also other business sectors.
Virtual Reality (VR) and Augmented Reality (AR) Transforming Medical Applications
Authors: Vashishth Tarun Kumar , Sharma Vikas , Sharma Kewal Krishan , Kumar Bhupendra , Chaudhary Sachin , Panwar Rajneesh
Published: October 2023

Virtual and augmented reality (VR/AR) technologies have emerged as transformative tools in the field of medical applications, revolutionizing healthcare practices and transforming the way medical professionals and patients engage with healthcare environments. This book chapter provides an in-depth exploration of the diverse range of applications where VR/AR is being utilized to enhance medical training, patient care, surgical planning, rehabilitation, and mental health treatments. It explores how VR/AR technologies are being leveraged to improve medical education and training, enabling healthcare professionals to practice complex procedures in realistic virtual environments. This book chapter also provides a comprehensive overview of the transformative role of VR/AR in medical applications. From education and training to patient care, surgical planning, rehabilitation, and mental health treatments, VR/AR technologies offer exciting possibilities to enhance healthcare delivery, improve patient outcomes, and shape the future of medicine.
Latest Advances in 3-D and 4-D FEM Simulation for Comprehensive Geomechanical and Geophysical Analysis of Unconventional Reservoirs, from Field Data to Numerical Models: Case Study Fm. Vaca Muerta, Argentina
Authors: Camus A. Sánchez , Ramos R. , Bianchi L.
Published: October 2023

The prime goal of the comprehensive characterization of unconventional reservoirs (organic-rich mudrocks) is to build 3-D and 4-D FEM numerical models for geomechanical and geophysical studies, such as seismic full-wave propagation, AVO or AVAz analysis, seismic inversion, well stability, hydraulic fracture propagation, cement shield and casing integrity, well to well interaction, choke management for optimal well production, tests for different landing zones, fault and layer reactivation risk cubes and other geomechanical attributes. The current technologies for the acquisition and processing of seismic data, well logs and well testing such as walkaround and walkaway VSPs, multicomponent (3C) seismic, microseismic, crossed dipole sonic logs, DFITs, etc., together with laboratory core measurements and modern rock physics models allow performing a mechanical characterization of the reservoir anisotropy, its strength properties and the stress field. This work presents a 3-D/4-D orthorhombic poroelastic geomechanical model of a vertical well in the Vaca Muerta formation (Neuquén Basin, Argentina), located in the oil generation window. The developed procedure starts from a mechanical (anisotropic) and petrophysical model, including a stress field characterization; at that point the initial reservoir conditions are reproduced. Then, a full-wave propagation synthetic seismogram (wave conversion modes), an AVO and an AVAz analysis are carried out, validating the direct model built. After that, the drilling process, casing and cement shield integrity, hydraulic fracturing and well production are simulated. As shown in this paper, these types of numerical simulations allow testing different scenarios, which helps to reduce uncertainty and anticipates issues that could affect hydrocarbon production or well integrity during the exploitation of the reservoir, leading to an increase in the return on the initial investment, which in unconventional reservoirs is very high.
Shadow masks as an alternative method to lithography for the structuring of thin film layers on LTCC substrates
Authors: Bartsch Heike , Jaziri Nesrine , Jaekel Konrad , Nessimian Norayr , Müller Jens
Published: October 2023

The combination of low temperature cofired ceramic multilayer technology with thin film deposition methods enables new functional principles by expanding the available portfolio of materials. Low-stress integration of micromechanical chips can be achieved, for example, by using reactive multilayers as local heat sources, which can be deposited directly onto the ceramics. Shadow masks are ideal for structuring these multilayers. The technology has the advantage that the layers are patterned without the use of etching chemicals and no residues of masking layers or photoresist remain on the non-coated areas. Flexible polyimide used to cover the non-coated areas can adapt to the surface unevenness of the ceramic. The polymer has excellent temperature stability and is compatible with vacuum coating processes. It is available in various thickness gradations and can be easily structured by laser cutting. The accuracy of the mask fabrication by means of laser cut is studied in this work. Structures with a line width of 30 μm can be precisely cut into 75 μm thick polyimide foils. Mask and chip are mechanically aligned, thus a positioning accuracy of 70 μm and better when using the outer edge of mask and chip for alignment is achievable. Major influences of the laser process on the precision of the mask and the resulting transfer fidelity to the ceramic surface are discussed. The method is suitable for reliably reproducing layers with structure sizes from 30 μm with a pitch of 150 μm.
Next Generation High Powered RF and Optical Packages
Authors: Kothandapani Ramesh , Li Tan Sin , Wei Tee Zhen , DeLeon Noel , Wang Chen , Johnson Christopher
Published: October 2023

RF signals are radio waves that are very crucial for telecommunications. Quality communications require reliable materials which are appropriately processed to house high-powered semiconductors such as GaN and GaAs. It is equally crucial to accommodate passive electronic components along with these semiconductors into the housings for the Next Generation RF package or GenPack™. Evolving semiconductor technologies demand fail-safe packages to protect the devices in all applications and environmental conditions. Future aircraft, EV cars, spacecraft, augmented and/ or virtual reality headsets, medical devices and many more technologies require operating at a higher power and frequency with a proper thermal and power management platform. The higher speeds of telecommunications hinge on the performance of semiconductors and their packages. Therefore, the GenPack™ and packaging process are becoming crucial pieces of the supply chain.

Rugged GenPack™ RF packages differ in several ways compared to the traditional air cavity packages. For instance, FR-4 or Flame-Retardant glass-reinforced epoxy laminate material can be replaced with Aluminum Nitride or Alumina Oxide, Silicon Nitride or even Sapphire. The switch offers mechanical bonding directly onto the thermal spreader. Traditional circuits created on printed circuit boards have limited ability to dissipate heat due to the low thermal conductivity of FR4. Circuits created on ceramic can dissipate higher amounts of heat. As in the organic FR4 boards, multiple vias can be formed in the ceramic substrates to create metal pads top the ceramic that are grounded to the flange beneath the ceramic.

A metal flange can be positioned beneath the ceramic to provide a heat spreader and electrical ground that can be bolted onto a heatsink. Flanges can be made from a diamond metal matrix composite instead of lower thermal conductivity materials to provide much more efficient thermal transfer. Furthermore, narrow leads offer optimized impedance at RF and microwave frequencies. A range of ceramic and flange materials can be selected to optimize GenPack™ RF Packages with cost, quality, and performance in considerations for the respective applications.
Lateral Intraventricular Epidermoid Cyst
Authors: Cheng Zhe , Fan Shun Z. , Sun Yu X. , Hu Yuan L. , Xin Ling , Dong Jun , Wang Da Wei
Published: October 2023

Epidermoid cysts originate from ectopic embryonic epithelial cells and are a very common type of benign intracranial tumor. However, the incidence of intraventricular epidermoid cysts is low, and lateral intraventricular epidermoid cysts are even rarer. Here, we present a case of lateral intraventricular epidermoid cyst and review the relevant literature. A 54-year-old female complained of recurrent headaches over a 5-year period, with aggravated symptoms during the last 2 months or more. A computed tomography of the brain showed a low-density mass in the lateral ventricle and enlargement of the right ventricle. Cranial magnetic resonance imaging further confirmed that the mass was an epidermoid cyst. The patient underwent microscopic surgical resection combined with endoscopy using an interhemispheric craniotomy approach. The mass was satisfactorily removed, and the patient recovered well. Lateral intraventricular epidermoid cysts often present with clinical symptoms due to the invasion of surrounding brain tissue or blockage of the cerebrospinal fluid system. Diagnosis relies on examination by magnetic resonance imaging, and treatment relies on surgical resection. The prognoses of patients are mostly excellent and depend on whether the tumor is resected cleanly or not.
Immunohistochemical evaluation of myofibroblasts in odontogenic keratocyst, dentigerous cyst and different clinical variants of ameloblastoma
Authors: Anusai V. V. , Shylaja S. , Suvarna M. , Ramanand O. V. , Reddy E. Sharath , Vamshi V. Raghu
Published: October 2023

Background:

Odontogenic cysts and tumors exhibit varying degrees of aggressiveness in their biological behavior. Odontogenic keratocyst (OKC), dentigerous cyst (DC), ameloblastoma are most common odontogenic cysts and tumors to occur in the oral cavity. Myofibroblasts (MFs) in the connective tissue stroma participate in the matrix degradation process by secreting matrix metalloproteinase 2, transforming growth factor beta1 and may contribute to variation in their biological behavior. Its activity is identified by alpha-smooth muscle actin (α-SMA) marker. With this background, the present study aims to evaluate the frequency of MFs using α-SMA to determine the biological behavior of OKC, DC, and different clinical variants of ameloblastoma.

Materials and Methods:

A retrospective study was carried out with total of 60 samples which include 10 cases each of OKC, DC, 30 cases of different clinical variants of ameloblastomas and 10 normal mucosa taken as controls. All are stained immunohistochemically using α-SMA and were analyzed for the same. Comparison between more than 2 groups done by one way analysis of variance test with the level of significance of P ≤ 0.0001, i.e., <0.05.

Results:

Statistically significant difference in the mean number of MFs observed between certain groups, with higher mean number in solid ameloblastoma (SA) (32.45) followed by OKC (28.79), unicystic ameloblastoma (24.53), desmoplastic ameloblastoma (7.44), and DC (1.72).

Conclusion:

Higher frequency of MFs noticed in SA, OKC which are key cells for connective tissue remodeling by interacting with epithelial cells and other connective tissue cells to facilitate progression of cysts and tumors thereby contributing to their biological behavior.
Effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement
Authors: Malekhoseini Zahra , Rezvani Mohammad Bagher , Niakan Mohammad , Atai Mohammad , Bassir Mahshid Mohammadi , Alizade Hamid Safar , Siabani Saba
Published: October 2023

Background:

To improve the limitations, many modifications in the resin-modified glass ionomer (RMGI) composition have been proposed. In this study, we evaluated the effect of different concentrations of zinc oxide (ZnO) nanoparticles incorporated into RMGI cement on its physical and antimicrobial properties.

Materials and Methods:

In this in vitro study, ZnO nanoparticles with 0–4 wt.% concentrations were incorporated into RMGI. The following tests were carried out: (a) Antibacterial activity against Streptococcus mutans tested by disc diffusion method, (b) mechanical behavior assessment by measuring flexural strength (FS) and flexural modulus (FM), (c) micro-shear bond strength (μ-SBS), and (d) fluoride and zinc release. Data were analyzed using the statistical tests of ANOVA, t-test, and Tukey's HSD post hoc in SPSS V22. The level of significancy was 0.05.

Results:

In the disc diffusion method, specimens with 2 wt.% ZnO nanoparticles showed the highest antimicrobial efficacy (P < 0.05). After 1 month of water storage, no significant difference was observed in FS and FM of the samples (P > 0.05). In 2 wt.% ZnO nanoparticles group, μSBS increased in the first 7 days but decreased by 17% after one month, which showed a significant difference with that of the control group. The fluoride release did no change in the ZnO nanoparticle-containing group compared with the control group at all time intervals.

Conclusion:

Incorporation of 2 wt.% ZnO nanoparticles into the RMGI cement adds antimicrobial activity to the cement without sacrificing FS and fluoride release properties, while decreased μSBS.
Effects of probiotic and fluoride mouthrinses on Streptococcus mutans in dental plaque around orthodontic brackets
Authors: Dadgar Sepideh , Heydarian Amin , Sobouti Farhad , Goli Hamidreza , Rakhshan Vahid , Heidari Mohadeseh
Published: October 2023

Background:

Although it is shown that probiotic agents might reduce Streptococcus mutans, no study has evaluated this effect in the form of probiotic mouthrinse. The purpose of this study was to compare the effect of probiotic experimental mouthwash Lactobacillus plantarum versus sodium fluoride and placebo mouthwashes on the number of S. mutans present in dental plaque around orthodontic brackets in fixed orthodontic patients.

Materials and Methods:

This study was a randomized clinical trial. The total of 38 patients participate consisting of 12 patients in the fluoride group, 13 in the probiotic, and 12 in the placebo group. They were given mouthwashes to use twice a day for 2 weeks. Plaque sampling was performed using the 4-pass technique in all three groups in two stages: before the intervention and after 2 weeks of using the mouthwash. The number of bacteria present in the dental plaque was then reported based on the number of colonies grown on agar medium. Data were analyzed using Kruskal–Wallis and Wilcoxon tests (α = 0.05).

Results:

Gender distribution, mean age, and protocol adherence were not significantly different among all three groups. After the intervention, the number of S. mutans present in the dental plaque followed an increasing manner in the placebo (P = 0.005) and probiotic (P = 0.158) groups and decreased in fluoride group (P = 0.025).

Conclusion:

The L. plantarum probiotic mouthwash was ineffective in reduction of S. mutans in dental plaque. However, fluoride mouthwash is considerably effective against S. mutans and thus recommended.
Early outcomes of limb salvage surgery with mega-prosthesis
Authors: Bilal Muhammad , Jilani Syed Rizwan-UL-Ahsan , Rafi Ilyas , Shakeel Osama , Jabeen Wardah
Published: October 2023

Objective:

To determine the early outcomes of limb salvage surgery with mega prosthesis.

Methods:

This retrospective study was conducted at Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&RC) from 1st January 2017 till 31st January 2020. Data like demographics, histopathology, functional and survival outcomes were retrieved from the Hospital Information System. Musculoskeletal Tumor Society (MSTS) score was used to evaluate the functional outcomes after the surgery. For survival analyses, Kaplan-Meier curve was applied. Prosthesis joint infection, amputation rate, metastasis, mortality rate, and recurrence were also recorded.

Results:

This study included 43 patients who underwent limb salvage surgery with endoprosthesis reconstruction at SKMCH&RC. The mean age at the time of diagnosis was (26.5±15.8) years. Patients with distal femoral replacement had the highest MSTS scores (81.45±9.70) while those with proximal humerus replacement has the lowest MSTS scores (56.8±11.2). There was a strong association between site of tumor and MSTS (F=3.30, P=0.017). We also found a correlation between surgical site infection and MSTS scores (r=0.484, P=0.001). Patients with recurrence also had significantly lower MSTS scores (P<0.05). The cumulative survival rate at the end of two-year follow-up was (71.4±17.1)% in proximal femur tumor patients, (88.0±7.8)% in distal femur tumor patients, and (50.0±3.5)% in proximal humerus tumor patients. Besides, patients with Ewing sarcoma had the highest survival rate (97.5±11.0)% while patients with chondrosarcoma had the lowest survival rate (77.8±13.9)%.

Conclusions:

Limb salvage surgery with mega-prosthesis can be performed with satisfactory functional and survival outcomes, but further studies are needed to compare it with other limb salvage methods. This study can be used as a reference for future studies.
Effect of taxifolin on cold-shock damages in spermatozoa in rabbits
Authors: Yılmaz İrfan , Türk Gaffari , Çakır Cihangiroğlu Aslıhan , Acısu Tutku Can , Güngör İbrahim Halil , Arkalı Gözde , Ekmen Edanur Güler
Published: October 2023

Objective:

To investigate the effect of taxifolin added to rabbit semen on freezing-induced cold-shock damages in spermatozoa.

Methods:

Semen was collected from six adult New Zealand rabbits once a week by artificial vagina. The collected semen was pooled at 38 °C and divided into four equal volumes. They were diluted with 0, 50, 100 and 200 μM taxifolin-containing Tris + egg yolk extender at 38 °C and their temperatures were lowered to 4 °C. Following equilibration, semen drawn into 0.25 mL straws were frozen in an automatic semen freezing device and stored in liquid nitrogen container at -196 °C. Samples were thawed in 38 °C water for 25 s and the analyses of motility, kinematic parameters, morphological deformities, changes in membrane integrity, mitochondrial membrane potential, dead-live ratio, acrosomal damages and as well as oxidative stress analyses were performed in semen.

Results:

Addition of 50 μM taxifolin significantly improved motility (total, progressive, rapid and static), high mitochondrial membrane potential and the ratios of spermatozoa with acrosomal damage compared to the control group. Compared to the control group, malondialdehyde (MDA) levels in the 50 and 100 μM taxifolin groups were significantly lower, while the MDA level was high and viable spermatozoa ratio was low in the 200 μM taxifolin group. There were no significant differences between the groups in terms of kinematic parameters, morphological deformities, membrane integrity and antioxidant levels.

Conclusions:

The low dose of taxifolin (50 μM) has a positive effect and the high dose (200 μM) has a negative effect. Therefore, it is concluded that the addition of low-dose (50 μM) taxifolin to the extenders would be a useful additive in reducing cold-shock damage that occurs during freezing of rabbit semen.
Outcomes of patients admitted to the intensive care unit with community-acquired pneumonia in a tertiary care center in Riyadh, Saudi Arabia
Authors: Oreibi Talal , Alenezi Farhan , Ahmed Amjad M. , Humaid Felwa Bin , Sadat Musharaf , Tamim Hani Mohammed , Baseet Faisal Fouad , Naidu Brintha , Arabi Yaseen M.
Published: October 2023

BACKGROUND:

Community-acquired pneumonia (CAP) is a leading cause of intensive care unit (ICU) morbidity and mortality. Despite extensive international epidemiological and clinical studies to improve those patients’ outcomes, local statistics in Saudi Arabia are limited. The objective of this study is to describe the clinical characteristics and outcomes of patients admitted to the ICU with the diagnosis of CAP reflecting the experience of a tertiary center over an 18-year period.

METHODS:

A retrospective cohort study included all consecutive adult ICU patients diagnosed with CAP between 1999 and 2017. Baseline demographics, patients’ risk factors, and initial admission laboratory investigations were compared between survivors and nonsurvivors. A multivariate regression model was used to predict mortality.

RESULTS:

During the study period, there were 3438 patients admitted to the ICU with CAP (median age 67 [Quartile 1, 3 (Q1, Q3) 51, 76] years) and 54.4% were males, of whom 1007 (29.2%) died. The survivors compared with nonsurvivors were younger (65 vs. 70 years), less likely to have chronic liver disease (2.4% vs. 10.5%), chronic renal failure (8.1% vs. 14.4%), and be immunocompromised (10.2% vs. 18.2%), and less frequently required mechanical ventilation or vasopressors (46.2% vs. 80.5% and 29.6% vs. 55.9%, respectively). Acute Physiology and Chronic Health Evaluation (APACHE) II score was significantly higher among nonsurvivors (median score 26 vs. 20) with a longer duration of mechanical ventilation and ICU stay. Using a multivariate regression model, age, APACHE II score, bilirubin level, vasopressors, and mechanical ventilation were significantly associated with increased mortality, while diabetes was associated with lower mortality.

CONCLUSION:

Around one-third of patients admitted to the ICU with CAP died. Mortality was significantly associated with age, APACHE II score, vasopressor use, and mechanical ventilation. A comprehensive national registry is needed to enhance epidemiological data and to guide initiatives for improving CAP patients’ outcomes.
Clinicodemographic characteristics and prognostic role of myasthenia gravis in thymoma: Experience from a Saudi population
Authors: Shammari Abdullah Al , Saad Aida , Saif Lama Tareq , Othman Safy A. , Ghosheh Mohammad J. , Khdeir Ghadir M. , Alashgar Omniyah , Abu-Rayya Mohammed A. , Ahmed Mohamed Hussein , AlKattan Khaled , Saleh Waleed
Published: October 2023

OBJECTIVES:

The objectives of the study were to determine the clinicodemographic characteristics and the prognostic role of myasthenia gravis (MG) in thymoma.

METHODS:

The records of patients who underwent surgical resection of thymoma at King Faisal Specialist Hospital and Research Center in the past 23 years were reviewed. Seventy thymoma patients were finally included and were then categorized based on MG status into the MG group (39 patients) and the non-MG group (31 patients). Collected data included patients’ demographic characteristics, tumor characteristics, and postoperative clinical outcomes. All analyses were conducted using SPSS. The comparison between both groups was tested using the Student t-test and Chi-square test for continuous and categorical variables, respectively. A P = 0.05 or less indicated statistical significance.

RESULTS:

Patients’ age ranged from 11 to 76 years, and female predominance was observed (55.7%). Compared to the non-MG group, no difference in patients’ gender was observed (P = 0.058); however, MG patients had a younger age (39.30 vs. 48.77, P = 0.0095). No difference was noted between both groups based on the World Health Organization classification (P = 0.398), but MG patients tended to present with less-advanced tumors based on the TNM classification (P = 0.039) and lower stage based on the MASAOKA staging system (P = 0.017). No significant change in tumor size (P = 0.077), resectability (P = 0.507), and adjuvant therapy (P = 0.075) were observed. MG was not significantly associated with postoperative complications, morbidity, or mortality. However, it exhibited a prognostic protective role in terms of lower recurrence (2.56% vs. 35.48%, P = 0.0001) and longer survival duration (18.62 vs. 10.21 years, P < 0.001) as compared to non-MG patients.

CONCLUSIONS:

MG occurrence in thymoma patients is more likely to occur at a younger age, higher TNM classification, and advanced MASAOKA stage. Although no significant association was noted between MG and complications and mortality, MG exhibited a protective role in thymoma by providing a lower recurrence rate and longer survival duration.
Do orthodontists aim to decrease the duration of fixed appliance treatment?
Authors: Abid Mushriq F. , Alhuwaizi Akram F. , Al-Attar Ali M.
Published: October 2023

OBJECTIVES:

The aim of the present study was to investigate the trends in the use of fixed appliance and accelerated orthodontics to decrease the treatment duration. Further, this study aimed to assess the effect of demographic factors on the participant's choice of treatment modality.

METHODS:

This was a cross-sectional study in the form of questionnaire-based online survey especially designed and distributed to 265 orthodontists via email. The questions aimed to collect basic information about the participants and respondents’ choices for decreasing the treatment duration. The data were analyzed according to gender, level of academic education and years of clinical experience using Chi-square test.

RESULTS:

A response rate of 85.2% was reported. Most of the orthodontists aimed to reduce the treatment duration by the biomechanical (66.8%) and surgical approaches (27.4%). The use of sliding mechanics (69.4%) and one-step retraction was more common (66.3%). MBT bracket prescription was more prevalent (51.7%), followed by Roth (41.1%). Conventional brackets were used more than self-ligating brackets, and aesthetic brackets were avoided by one third of the respondents. NiTi wires were the most commonly used wires during the alignment stage (44.2%). However, the effect of gender, years of clinical experience and specialty level of education showed some effects on the use of certain techniques and clinical practice of the respondents.

CONCLUSIONS:

Most of the orthodontists aimed to decrease orthodontic treatment duration by using biomechanical and surgical approaches. Gender and clinical experience to a certain extent affected the participants’ choice during orthodontic treatment.
Sarıcakaya (Eskişehir) Granitoyidindeki Pegmatitlerin Kökeni ve Endüstriyel Hammadde Potansiyeli
Authors: GÜLLÜ Bahattin , BİLGİLİOĞLU Hacer
Published: October 2023

Eskişehir kuzeyindeki Sarıcakaya Granitoidindeki pegmatitlerin ana mineralojik bileşeni plajiyoklaz, ortoklaz, kuvars, biyotit, ±granat, ±muskovit, ±epidot’tur. Konfokal raman spektroskopi çalışmalarında plajiyoklaz minerallerinin albit-oligoklaz, granatların ise çoğunlukla spessartin bileşimde oldukları görülmektedir. Endüstriyel hammadde olarak kullanılabilme potansiyeline sahip pegmatitler ana kaya ile keskin dokanaklı olup, serizitleşme ve killeşme gösterirler.

Pegmatitlerin A/NK (mol%) oranı 0.96-1,79 (ortalama 1,32), A/CNK (mol%) oranları 0.82-1.55 (ortalama:1,07) arasında değişmekte olup metalümin-peralümin karakteri yansıtmaktadır. Zirkon ve apatit doygunluk sıcaklıkları pegmatitleri oluşturan magmanın ortalama sıcaklığının 678,7-766,7°C aralığında değiştiğini göstermektedir. ORG’ye göre normalize edilen örümcek diyagramlarda kabuksal kirlenmenin etkilerinin gözlendiği pegmatitlerin, Sarıcakaya granitoidini oluşturan magmanın pegmatitik-pnömatolitik evredeki kristallenen magmatik birimleri olduğu düşünülmektedir.
Medida de la influencia de una propuesta de valor sustentable en empresas de retail. Caso: “multitiendas” de la Región de Coquimbo – Chile
Authors: Cabana Villca Segundo Ricardo , Aguilera Mauricio , Ramírez Vega Camila Constanza , Rojas Godoy Juan Carlos Antonio
Published: October 2023

En el contexto global relacionado con la crisis social y ambiental, este artículo tiene como objetivo realizar un análisis de las variables que influyen en la competitividad de las empresas multitiendas de la Región de Coquimbo, Chile, a partir de la formulación y uso efectivo de una propuesta de valor sustentable. Se presenta un modelo causal compuesto por siete hipótesis, con seis variables de estudio: propuesta de valor sustentable (socio-ambiental), fidelidad del cliente, co-creación de valor, innovación sustentable, eco-eficiencia y, competitividad empresarial. La población objetivo, mediante muestra representativa de 383 personas, son los consumidores de las principales tiendas del retail regional. Para el contraste del modelo propuesto se emplea el método de ecuaciones estructurales, a través de los Mínimos Cuadrados Parciales (PLS). Se determina que las hipótesis planteadas son aceptadas y que los factores señalados explican en un 89,9% la varianza de la competitividad empresarial.
Peran dan Fungsi Badan Permusyawaratan Desa (BPD) dalam Penyelenggaraan Pemerintahan Desa di Desa Kedaton Kecamatan Kapas Kabupaten Bojonegoro
Authors: Astono Tony Rudi
Published: October 2023

This research aims to analyze the role and function of the Village Consultative Body (BPD) in implementing village governance in Kedaton Village, Kapas District, Bojonegoro Regency. BPD is an institution that has an important role in carrying out village government tasks and representing the interests of the community. The research method used is a qualitative approach with data collection techniques through interviews, observation and documentation studies. The respondents for this research consisted of members of the BPD, village officials, and the people of Kedaton Village. The research results show that BPD has a significant role and function in implementing village governance. The role of the BPD includes the legislative function, namely producing village regulations through village deliberations. BPD also has a supervisory function over the performance of village officials and the implementation of village development programs. Apart from that, the BPD acts as an intermediary between the community and the village government in overcoming problems and conveying community aspirations. Based on the research results, it is recommended that village and district governments pay more attention to BPD by providing adequate support, both in terms of budget and human resources. Apart from that, it is necessary to provide outreach and education to the community about the role and function of the BPD so that they can better understand the importance of this institution in implementing village governance.
Advanced Management of the Burn Patient
Authors:   Hospital General Dr. Daniel Gurria Urgell ISSSTE Villahermosa, Delgado Katia Esthefany Hernández , Ursua Tovar Patricia Montzerrat ,   Hospital General Manzanillo (SSA), Herrera David Alejandro Rodriguez ,   Unidad Médica de Alta Especialidad No. 71 IMSS, Torreon, Coahuila., López José David Simonin ,   Hospital Regional de Río Blanco SSA, Río Blanco, Veracruz., Garza López Ernesto Alejandro ,   Facultad de Medicina, UANL., Estevez Daniel Isai Paniagua ,   Hospital General de Zona No. 71 IMSS., Sanchez Valle Paloma Kristal ,   Universidad Michoacana de San Nicolás de Hidalgo, Martinez Bravo Victor Mario ,   Hospital Regional de alta especialidad ISSSTE Veracruz
Published: October 2023

Burn injuries are a significant public health concern, with a substantial global burden. These injuries can result in complex, life-threatening situations that require advanced management strategies. This review explores the epidemiology, significance, and advanced management of burn patients. We delve into the theoretical framework, covering definitions, risk factors, complications, and various management approaches. The discussion highlights the latest advances in burn care, including early burn wound excision, fluid resuscitation, infection control, and rehabilitation. The evolving landscape of burn care research and its implications for improved patient outcomes are emphasized. In conclusion, this article underscores the importance of a multidisciplinary approach to burn patient care and the need for continued research to enhance the quality of life for survivors.
Role of Methylene Blue in Refractory Anaphylaxis -A Case Report
Authors:   Consultant. Department of critical care medicine. Mar sleeve medicity Pala 686584, Mathew Dr. Josekutty , K.F. Dr. Anooja ,   Consultant. Department of critical care medicine. Mar sleeve medicity Pala 686584, Ahammed Dr. Nijaz ,   Consultant. Department of critical care medicine. Mar sleeve medicity Pala 686584, Manohar Dr. Vishnu ,   Consultant. Department of critical care medicine. Mar sleeve medicity Pala 686584
Published: October 2023

Refractory anaphylaxis is defined as anaphylaxis which, after treatment with at least 2 doses of minimum 300 microgram epinephrine, does not achieve normalization of symptoms. Dysregulation of NO synthesis and vascular smooth cell guanylate cyclase activation may have a role in refractory vasoplegia. Methylene blue is competitive inhibitor of NO synthase and guanylate cyclase. Thus, blocking the effects on cGMP mediated smooth muscle relaxation and vasodilation and mast cell mediator release. Thus, methylene blue has been implicated as a treatment option for refractory vasoplegia. We present the case of a 21-year-old male who presented with anaphylactic shock that was unresponsive to epinephrine. After administration of methylene blue, his blood pressure and sensorium improved; and he was gradually extubated. Hence, our clinical experience suggests that methylene blue is a safe treatment option for refractory anaphylactic shock.
Diagnostic Challenges of Vascular Rings: Insights from a Case Report
Authors:   ISSSTE Hospital 1° de Octubre, Mexico City., Hayashi-Mercado César , González-Urueta Miguel ,   UABC, Baja California, México., Luna-López Gabriel ,   ISSSTE Hospital 1° de Octubre, Mexico City., González Gallo Oscar ,   ISSSTE Hospital 1° de Octubre, Mexico City., Aguilar Abelardo-Alexanders ,   West, Hospital Militar Escuela Dr. ADB 2254, Managua, Nicaragua.
Published: October 2023

The vascular ring (VR) is a rare congenital anomaly that can cause compression of the trachea or esophagus, resulting in respiratory and/or gastrointestinal symptoms. The severity of symptoms depends on the type of VR, with patients who have anatomically complete VRs typically presenting earlier in life. The diagnosis of VR has advanced with the availability of improved imaging modalities. Prenatal diagnosis is possible with fetal echocardiogram, while non-invasive multidetector CT and MRA can be utilized for later diagnosis. These imaging modalities allow for the delimitation of the defect and the identification of the anatomy for treatment planning. This case report presents the evaluation and management of a male neonate who was diagnosed with VR after initially presenting with respiratory and gastrointestinal symptoms that were suspected to be related to gastroesophageal reflux. This case highlights the importance of considering VR in the differential diagnosis of patients presenting with these symptomatologies.
The Effect of Participatory Leadership Style and Work Motivation on Employee Performance through Job Satisfaction at the Malang City District Office
Authors:   University of Merdeka Malang, Indonesia, Wadu Marcella Felisitas , Triatmanto Boge ,   University of Merdeka Malang, Indonesia, Setiyadi Sina ,   University of Merdeka Malang, Indonesia
Published: October 2023

This study has at least four aims to carry out. Such as describing participatory leadership style, work motivation, employee job satisfaction, and employee performance. Also, analyze the effect of participatory leadership style and work motivation on employee job satisfaction. Examine the effect of participatory leadership style and work motivation on employee performance and analyze the effect of employee job satisfaction on employee performance at the sub-district office in Malang City. The population in this study were Civil Servants at the Malang City District Office, amounting to 114 employees. The sample was taken using the slovin formula because the respondents were more than 100 employees, so 88 employees became the object of the research. The data analysis technique used is path analysis. The results show that participatory leadership style and work motivation affect employee job satisfaction. Participative leadership style and work motivation affect employee performance. Also, employee job satisfaction affects employee performance. Participatory leadership style and work motivation affect employee performance through employee job satisfaction.
The Influence of the Implementation of CHSE (Cleanliness, Health, Safety, and Environmental Sustainability), E-WOM, and Trust on the Purchase Intention of Star-Rated Hotels in Lampung
Authors:   The Faculty of Economics and Business, University of Lampung, Indonesia., Prakoso Setiatmoko Adi , Bangsawan Satria ,   The Faculty of Economics and Business, University of Lampung, Indonesia., Pandjaitan Dorothy Rouly H. ,   The Faculty of Economics and Business, University of Lampung, Indonesia.
Published: October 2023

The goal of this study is to establish the influence connection among Cleanliness, Health, Safety, and Environmental Sustainability (CHSE), Electronic Word of Mouth (E-WOM), and trust on the purchase intention of star-rated hotels in Lampung, Indonesia. This study was conducted in the post-Covid-19 period. Employing a quantitative descriptive study design, six hypotheses were formulated and examined utilizing covariance-according to structural equation modeling (CBSEM), by AMOS 24.0 software. We collected 310 respondent samples utilizing purposive sampling techniques. Empirical outcomes show that the variables CHSE, E-WOM, and trust all influence purchase intention, by the connection among CHSE and trust having the most significant impact. The trust variable exhibits a longer influence compared to the other variables. The study outcomes show that all six proposed hypotheses were accepted. CHSE is highly effective in enhancing consumer trust and is directly proportional to the increase in consumer purchase intention. As a result, CHSE has not only become a common standard in the travel enterprise for the Covid-19 but can also serve as the standard for delivering tourism assistances in the current new normal era. CHSE can fulfill the desires and needs of customers, instilling confidence in them to return and stay at hotels.
Simposio 4: Fertilización asistida y diabetes mellitus materna
Authors: Geller Marisa
Published: October 2023

La diabetes mellitus (DM) tipo 1 y 2 se ubican dentro de las enfermedades crónicas más prevalentes en las mujeres en edad reproductiva. A su vez, son pacientes con alteraciones en su fertilidad donde se observa que tienen menor descendencia que sus pares y varias deben hacer tratamientos de fertilidad de alta complejidad.

La hiperglucemia de la DM1 (por el déficit de insulina) y la hiperinsulinemia (por la administración exógena) pueden inducir al hipogonadismo, ovarios de aspecto poliquístico e hiperandrogenismo. En el caso de la DM2, las pacientes pueden presentar síndrome de ovario poliquístico (SOP), obesidad, insulinorresistencia e inflamación crónica, todo esto explica la mayor dificultad para lograr un embarazo.
Impacto de los tratamientos para el control glucémico en la insuficiencia cardíaca
Authors: Sanabria Hugo
Published: October 2023

La diabetes mellitus (DM) es un factor de riesgo independiente para el desarrollo de insuficiencia cardíaca (IC). El riesgo de desarrollar esta complicación es dos a cuatro veces mayor en hombres y cinco veces superior en mujeres con DM. Ante este escenario es imprescindible conocer el efecto de los diferentes grupos farmacológicos que utilizamos para el control glucémico sobre el riesgo de desarrollar IC, como así también una vez presentado el cuadro clínico, su rol pronóstico.

La metformina está contraindicada en pacientes con IC y filtrado glomerular <30 ml/min debido a un mayor riesgo de desarrollar acidosis láctica. Su uso en pacientes estables no incrementaría este riesgo e incluso estudios caso control evidenciaron cierto efecto beneficioso en esta subpoblación, aunque este impacto no fue demostrado en ensayos clínicos randomizados. Las tiazolidinedionas, agonistas PPARγ, como la pioglitazona y rosiglitazona están claramente asociadas a un riesgo mayor de internaciones por IC. Este riesgo si bien no parece acompañarse de un incremento en la mortalidad, se asocia a un aumento del empleo de diuréticos y de internaciones por lo cual está contraindicado en pacientes con diagnóstico de IC y debe usarse con precaución en pacientes con alto riesgo de desarrollarlo.
Omega 3: ¿Debemos indicarlo en nuestros pacientes?
Authors: Milikowski Marta
Published: October 2023

Los lípidos se identifican como un componente fundamental de la dieta porque desarrollan funciones muy importantes. Influyen en la modulación de las funciones inmunitarias y en los procesos inflamatorios atribuible a los ácidos grasos poliinsaturados de cadena larga (long chain polyunsaturated fatty acids, LCPUFA).

Los ácidos grasos esenciales (AGE), como el ácido linoleico (AL) y el α-linolénico (AAL), deben incorporarse con la dieta porque el organismo no los sintetiza.
Impacto de la actividad física: ¿cómo prescribirla?
Authors: Minuchín Gabriel
Published: October 2023

Anualmente la American Diabetes Association (ADA) realiza recomendaciones sobre cuidados y tratamientos de pacientes con diabetes mellitus (DM)1. Sería muy sencillo seguir prolijamente dichas recomendaciones para el beneficio de los individuos con DM o para quienes tienen riesgo de padecerla, sin embargo, no se cumplen, lo que provoca serios perjuicios para la salud.

Existen numerosas barreras para la prescripción adecuada de la actividad física (AF) por parte de los médicos2 y numerosas causas referidas por pacientes para no practicarla3.
Mecanismos independientes del descenso de peso
Authors: Álvarez María
Published: October 2023

Desde la década de 1930 existen reportes de casos aislados de mejoría de la hiperglucemia luego de cirugías gástricas por cáncer o enfermedad úlcero-péptica.

A partir de la cirugía bariátrica, con el objetivo de la pérdida de peso en pacientes con obesidad severa (del griego baros: peso, iatrikos: tratamiento), se observó la remisión de la diabetes mellitus tipo 2 (DM2) en el posoperatorio inmediato. El hallazgo inesperado de remisión de la DM con la cirugía bariátrica abre el campo de estudio del tubo digestivo como un órgano endocrino poderoso capaz de regular el apetito, el metabolismo energético y el metabolismo de la glucosa.
Simposio 18: Plan de alimentación y actividad física: impacto cardiovascular
Authors: Morejón Andrea
Published: October 2023

Las intervenciones sobre el estilo de vida, la alimentación y la actividad física constituyen sin lugar a dudas una de las herramientas fundamentales en la prevención y tratamiento de la obesidad, así como de las comorbilidades asociadas al peso. Su adecuada implementación brinda beneficios no solo propios de las intervenciones, alimentación y actividad física, sino también permiten mejorar los resultados con terapias concomitantes para el tratamiento de la obesidad, sus comorbilidades y reducir el riesgo cardiovascular1.

Con respecto al rol de la alimentación, se ha evaluado una diversidad de planes alimentarios, los cuales se diferencian principalmente en cuanto a la proporción y/u origen de los macronutrientes. Por ejemplo, planes de estilo mediterráneo, vegetariano, DASH demostraron mejorar en distinta medida parámetros cardiometabólicos2. Sin embargo, es importante considerar que deben tenerse en cuenta múltiples aspectos individuales y socioculturales al momento de diseñar un plan alimentario y, por lo tanto, no existe un patrón de alimentación saludable único que pueda implementarse de manera universal e invariable para obtener beneficios sobre la salud. De lo que sí se dispone de evidencia en la actualidad, es de la relación perjudicial del consumo habitual de productos ultraprocesados, los cuales incrementan de un 4 a un 9% tanto la enfermedad como la mortalidad cardiovascular3, por lo cualsu consumo debería desalentarse.