bluuebunny/crossref_metadata_2025 huggingface dataset:
Author Correction: Synthesis and characterization of polyethylene glycol-phenol-formaldehyde based polyurethane composite
Authors: Liu Juan , Chen RiQing , Wang ChunPeng , Zhao YongJun , Chu FuXiang
Published: March 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Publisher Correction: The ESA Swarm mission to help ionospheric modeling: a new NeQuick topside formulation for mid-latitude regions
Authors: Pezzopane M. , Pignalberi A.
Published: March 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Author Correction: The roles of p38 MAPK → COX2 and NF-κB → COX2 signal pathways in age-related testosterone reduction
Authors: Zhao Yu , Liu Xuehui , Qu Yine , Wang Lixuan , Geng Dan , Chen Wei , Li Li , Tian Yangyang , Chang Shiyang , Zhao Chunfang , Zhao Xiujun , Lv Pin
Published: March 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Author Correction: Targeted memory reactivation during sleep boosts intentional forgetting of spatial locations
Authors: Schechtman Eitan , Witkowski Sarah , Lampe Anna , Wilson Brianna J. , Paller Ken A.
Published: March 2020

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Seeing other perspectives: evaluating the use of virtual and augmented reality to simulate visual impairments (OpenVisSim)
Authors: Jones Pete R. , Somoskeöy Tamás , Chow-Wing-Bom Hugo , Crabb David P.
Published: March 2020

Simulations of visual impairment are used to educate and inform the public. However, evidence regarding their accuracy remains lacking. Here we evaluated the effectiveness of modern digital technologies to simulate the everyday difficulties caused by glaucoma. 23 normally sighted adults performed two everyday tasks that glaucoma patients often report difficulties with: a visual search task in which participants attempted to locate a mobile phone in virtual domestic environments (virtual reality (VR)), and a visual mobility task in which participants navigated a physical, room-scale environment, while impairments were overlaid using augmented reality (AR). On some trials, a gaze-contingent simulated scotoma—generated using perimetric data from a real patient with advanced glaucoma—was presented in either the superior or inferior hemifield. The main outcome measure was task completion time. Eye and head movements were also tracked and used to assess individual differences in looking behaviors. The results showed that the simulated impairments substantially impaired performance in both the VR (visual search) and AR (visual mobility) tasks (both P < 0.001). Furthermore, and in line with previous patient data: impairments were greatest when the simulated Visual Field Loss (VFL) was inferior versus superior (P < 0.001), participants made more eye and head movements in the inferior VFL condition (P < 0.001), and participants rated the inferior VFL condition as more difficult (P < 0.001). Notably, the difference in performance between the inferior and superior conditions was almost as great as the difference between a superior VFL and no impairment at all (VR: 71%; AR: 70%). We conclude that modern digital simulators are able to replicate and objectively quantify some of the key everyday difficulties associated with visual impairments. Advantages, limitations, and possible applications of current technologies are discussed. Instructions are also given for how to freely obtain the software described (OpenVisSim).
Unraveling the RNA modification code with mass spectrometry
Authors: Lauman Richard , Garcia Benjamin A.
Published: March 2020

The discovery and analysis of modifications on proteins and nucleic acids has provided functional information that has rapidly accelerated the field of epigenetics.
Benchtop access to anhydrous actinide N-donor coordination complexes using ionic liquids
Authors: Kelley Steven P. , Smetana Volodymyr , Emerson Stephen D. , Mudring Anja-Verena , Rogers Robin D.
Published: March 2020

Actinide salts were dehydrated with an ionic liquid containing the same anion and subsequently coordinated by N-heterocyclic ligands challenging the concept of O- over N-donor preference.
Boron nanostructures obtainedviaultrasonic irradiation for high performance chemiresistive methane sensors
Authors: Jha Ravindra Kumar , Nanda Aman , Bhat Navakanta
Published: March 2020

Boron nanostructures obtainedviaa top-down approach can be efficiently used as the receptor in chemiresistive methane gas sensors.
Preparation and biological properties of silk fibroin/nano-hydroxyapatite/graphene oxide scaffolds with an oriented channel-like structure
Authors: Wang Lu , Fang Min , Xia Yijing , Hou Jiaxin , Nan Xiaoru , Zhao Bin , Wang Xiangyu
Published: March 2020

A novel SF/nHAp/GO hybrid scaffold with oriented channel-like structure in bone tissue engineering.
Protective effects of aqueous extract from Gei Herba on blood-deficiency mice: insights gained by a metabolomic approach
Authors: Zhao Ruru , Mu Wenbi , Wang Xiaoning , Yang Sha , Duan Cancan , Zhang Jianyong
Published: March 2020

The protective effect and mechanism of Gei Herba in BD mice were revealed by classical and metabolomic perspectives.
Gold nanoparticle–cellulose/PDMS nanocomposite: a flexible dielectric material for harvesting mechanical energy
Authors: Pusty Manojit , Shirage Parasharam M.
Published: March 2020

A gold nanoparticle–cellulose/PDMS based piezoelectric nanogenerator (PNG) is reported in this work. The PNG delivers an efficiency of 1.8%. It can light LEDs and sense finger touch.
Trace manganese detection via differential pulse cathodic stripping voltammetry using disposable electrodes: additively manufactured nanographite electrochemical sensing platforms
Authors: Rocha Diego P. , Foster Christopher W. , Munoz Rodrigo A. A. , Buller Gary A. , Keefe Edmund M. , Banks Craig E.
Published: March 2020

Additive manufacturing is a promising technology for the rapid and economical fabrication of portable electroanalytical devices.
Highly sensitive and selective optosensing of quercetin based on novel complexation with yttrium ions
Authors: Nghia Nguyen Ngoc , Huy Bui The , Lee Yong-Ill
Published: March 2020

A simple and fast method was developed for the determination of quercetin using a Arduino-based portable device.
Correction: Opposite responses of normal hepatocytes and hepatocellular carcinoma cells to substrate viscoelasticity
Authors: Mandal Kalpana , Gong Ze , Rylander Alexis , Shenoy Vivek B. , Janmey Paul A.
Published: March 2020

Correction for ‘Opposite responses of normal hepatocytes and hepatocellular carcinoma cells to substrate viscoelasticity’ by Kalpana Mandal et al., Biomater. Sci., 2020, 8, 1316–1328.
White-light emission from a pyrimidine–carbazole conjugate with tunable phosphorescence–fluorescence dual emission and multicolor emission switching
Authors: Ishi-i Tsutomu , Tanaka Honoka , Park In Seob , Yasuda Takuma , Kato Shin-ichiro , Ito Mitsunori , Hiyoshi Hidetaka , Matsumoto Taisuke
Published: March 2020

White light emission based on multicolor switching of tunable phosphorescence–fluorescence dual emission was studied.
A new FRET probe for ratiometric fluorescence detecting mitochondria-localized drug activation and imaging endogenous hydroxyl radicals in zebrafish
Authors: Deng Tao , Wang Xiaojuan , Wu Shengjun , Hu Shiyou , Liu Wei , Chen Tongkai , Yu Zhiqiang , Xu Qin , Liu Fang
Published: March 2020

A new FRET probe has been prepared and successfully used for imaging hydroxyl radicals generated by drug activation and endogenous hydroxyl radicals in zebrafish.
Water-soluble pH-switchable cobalt complexes for aqueous symmetric redox flow batteries
Authors: Wang Hao , Sayed Sayed Youssef , Zhou Yuqiao , Olsen Brian C. , Luber Erik J. , Buriak Jillian M.
Published: March 2020

A water soluble cobalt complex with two redox couples that fall within the water splitting window can be applied as both the posolyte and negolyte in an aqueous symmetric redox flow battery.
Design of potent Mincle signalling agonists based on an alkyl β-glucoside template
Authors: Smith Dylan G. M. , Hosono Yuki , Nagata Masahiro , Yamasaki Sho , Williams Spencer J.
Published: March 2020

Potent signalling agonists of the innate immune receptor Mincle were developed that can be easily prepared from the surfactants octyl and lauryl β-d-glucoside.
Facet engineering in metal organic frameworks to improve their electrochemical activity for water oxidation
Authors: Wan Jiawei , Liu Di , Xiao Hai , Rong Hongpan , Guan Sheng , Xie Feng , Wang Dingsheng , Li Yadong
Published: March 2020

We present a facile and low-cost method to shape ZIF into 2D nanosheets with exposed (002) facets and discover that they exhibit excellent activity for oxygen evolution reaction.
Selenolesterase enzyme activity of carbonic anhydrases
Authors: Angeli Andrea , Carta Fabrizio , Donnini Selene , Capperucci Antonella , Ferraroni Marta , Tanini Damiano , Supuran Claudiu T.
Published: March 2020

An unprecedented carbonic anhydrase-mediated hydrolysis of selenolesters enables the release of selenolates, acting as potent CA inhibitors. A wide range of functionalised selenolesters, smoothly achieved from the corresponding selenols, are studied.
Electrochemical formation of N,N′-diarylhydrazines by dehydrogenative N–N homocoupling reaction
Authors: Breising Valentina M. , Kayser Jacob M. , Kehl Anton , Schollmeyer Dieter , Liermann Johannes C. , Waldvogel Siegfried R.
Published: March 2020

A novel electrochemical access to N,N′-diarylhydrazines is developed using commercial anilines, a simple setup, and an ecologically efficient electrolyte system.
Electrochemical nickel-catalyzed Migita cross-coupling of 1-thiosugars with aryl, alkenyl and alkynyl bromides
Authors: Zhu Mingxiang , Alami Mouad , Messaoudi Samir
Published: March 2020

An efficient electrochemical route towards the synthesis of thioglycosides is reported. This approach involves a S–C cross-coupling from protected and unprotected thiosugars with aryl bromides under base free conditions.
Iron-catalysed alkylation of 2-methyl and 4-methyl azaarenes with alcohols via C–H bond activation
Authors: Kabadwal Lalit Mohan , Bera Sourajit , Banerjee Debasis
Published: March 2020

Iron-catalysed alkylation of methylazaarenes with primary alcohols is presented. The catalytic protocol is highly selective for the alkylation process and generates water as a by-product.
Engineering surface and morphology of La/WO3 for electrochemical oxygen reduction
Authors: Ramani Swetha , Yin Zhewen , Miller Bradley , Bhethanabotla Venkat R. , Kuhn John N.
Published: March 2020

Lanthanum derived crystal and defect engineering for enhanced ORR performance in WO3.
Remarkable enhancement of photoluminescence and persistent luminescence of NIR emitting ZnGa2O4:Cr3+ nanoparticles
Authors: Srivastava Bhupendra B. , Gupta Santosh K. , Mao Yuanbing
Published: March 2020

A modified hydrothermal route with slow precipitation kinetics and core-shell strategies to synthesize ZnGa2O4:Cr3+ nanoparticles which demonstrate much-improved photoluminescence and persistent luminescence for bioimaging applications.
Reactive molecular dynamics simulations on the thermal decompositions and oxidations of TKX-50 and twinned TKX-50
Authors: Li Jing , Jin Shaohua , Lan Guanchao , Chen Shusen , Shu Qinghai , Li Lijie , Chen Kun
Published: March 2020

The influence of twinned crystals on the performance of TKX-50 is investigated using normal TKX-50 and twinned TKX-50 supercells. ReaxFF-lg reactive molecular dynamics simulations are performed to study thermal decomposition and oxidation.
Na2MnIII6LnIII clusters with a non-equivalent core: chiral vs. meso isomerism
Authors: Mayans Júlia , Font-Bardia Mercè , Escuer Albert
Published: March 2020

Chiral and racemic clusters with the Na2MnIII6LnIII core and different coordination numbers around the LnIII cation provide rare examples of symmetry dependent isomerism.
Colorimetric absorbance mapping and quantitation on paper-based analytical devices
Authors: Soda Yoshiki , Robinson Kye J. , Cherubini Thomas J. , Bakker Eric
Published: March 2020

A pixel-level colorimetric absorbance analysis can measure the total quantity of dye on paper, irrespective of shape and size.
Low-frequency flexural wave based microparticle manipulation
Authors: Bachman Hunter , Gu Yuyang , Rufo Joseph , Yang Shujie , Tian Zhenhua , Huang Po-Hsun , Yu Lingyu , Huang Tony Jun
Published: March 2020

An acoustofluidic particle manipulation platform that uses low frequency flexural waves produced by commercial transducers.
A liquid biopsy-guided drug release system for cancer theranostics: integrating rapid circulating tumor cell detection and precision tumor therapy
Authors: Xu Chun-Miao , Tang Man , Feng Jiao , Xia Hou-Fu , Wu Ling-Ling , Pang Dai-Wen , Chen Gang , Zhang Zhi-Ling
Published: March 2020

A system integrating diagnostic and therapeutic functions for cancer is presented using magnetically controlled microfluidics.
Fragmentation method reveals a wide spectrum of intramolecular hydrogen bond energies in antioxidant natural products
Authors: Singh Vijay , Ibnusaud Ibrahim , Gadre Shridhar R. , Deshmukh Milind M.
Published: March 2020

Very strong and weak IHBs in curcumin.
A recyclable colorimetric probe: in situ fabrication of highly stable HPEI–AuNPs for selective Ag+ detection
Authors: Bian Jie , Xia Yunxia , Sang Luyan , Zhu Chenxue , Li Yuxi , Li Guiying , Liu Xunyong , Wang Xing , Liu Yi
Published: March 2020

A highly stable and recyclable AuNP-based colorimetric sensor was prepared by an in situ reduction reaction and can detect Ag+ with high selectivity.
The presence of mixed-valent silver in the uranyl phenylenediphosphonate framework
Authors: Bai Ru , Chen Lanhua , Zhang Yugang , Chen Long , Diwu Juan , Wang Xiao-Feng
Published: March 2020

A 2-D silver uranyl phosphonate presents both Ag+ and Ag0 atoms in the free space between the adjacent layers and the incorporation of the mixed-valent silver sites results in the quenching of the fluorescent emission.
Controlling the selectivity of an intramolecular Friedel–Crafts alkylation with alkenes using selenium under mild conditions
Authors: Liao Ming-Hong , Zhang Meng , Hu Dai-Hui , Zhang Rui-Han , Zhao Yan , Liu Shan-Shan , Li Yun-Xia , Xiao Wei-Lie , Tang E
Published: March 2020

An efficiently divergent intramolecular Friedel–Crafts alkylation by unactivated alkenes with seleniranium ion-controlled Markovnikov/anti-Markovnikov specificities under mild conditions has been investigated.
A concerted evolution of supramolecular interactions in a {cation; metal complex; π-acid; solvent} anion-π system
Authors: Kuzniak Emilia , Hooper James , Srebro-Hooper Monika , Kobylarczyk Jedrzej , Dziurka Magdalena , Musielak Bogdan , Pinkowicz Dawid , Raya Jesus , Ferlay Sylvie , Podgajny Robert
Published: March 2020

Comprehensive studies on a concerted evolution of supramolecular interactions with multicomponent synthon reproduction provide a new tool to describe the trapping of flat [M(L)4]2− complexes within π-acidic cavities.
A bifunctional CoP/N-doped porous carbon composite derived from a single source precursor for bisphenol A removal
Authors: Tong Wenhua , Xie Yi , Hu Wanrong , Peng Yuanyuan , Liu Wenbin , Li Yonghong , Zhang Yongkui , Wang Yabo
Published: March 2020

Cost-effective and environmentally benign biomass precursor enabled synthesis of CoP/N-doped porous carbon nanocomposite for BPA removal through adsorption and peroxymonosulfate activation.
Reversible photoactivation in coordination polymer-derived CdS/Co–N species composites for enhanced photocatalytic hydrogen evolution
Authors: Guo Yuxiao , Yang Yawei , Yin Xingtian , Liu Jie , Que Wenxiu
Published: March 2020

An industrial-scale production of atomic-level cobalt-anchored CdS photocatalysts.
Evolution of Ni/Li antisites under the phase transition of a layered LiNi1/3Co1/3Mn1/3O2 cathode
Authors: Gao Ang , Sun Yang , Zhang Qinghua , Zheng Jieyun , Lu Xia
Published: March 2020

A suitable mechanism is proposed for the evaluation of Ni/Li antisites and Li diffusion in the layered Li1−xN1/3C1/3M1/3O2 cathode.
Polymer and magnetic nanoparticle composites with tunable magneto-optical activity: role of nanoparticle dispersion for high verdet constant materials
Authors: Pavlopoulos N. G. , Kang K. S. , Holmen L. N. , Lyons N. P. , Akhoundi F. , Carothers K. J. , Jenkins S. L. , Lee T. , Kochenderfer T. M. , Phan A. , Phan D. , Mackay M. E. , Shim I. B. , Char K. , Peyghambarian N. , LaComb L. J. , Norwood R. A. , Pyun J.
Published: March 2020

The critical role of nanoparticle dispersion on Faraday rotator activity was studied, revealing new routes for fabricating “plastic garnets” as low cost alternatives to existing inorganic materials for optical isolation and magnetic sensing.
Morphology and properties of PEDOT:PSS/soft polymer blends through hydrogen bonding interaction and their pressure sensor application
Authors: Tseng Yin-Tse , Lin Yan-Cheng , Shih Chien-Chung , Hsieh Hui-Ching , Lee Wen-Ya , Chiu Yu-Cheng , Chen Wen-Chang
Published: March 2020

The effects of the composition on the stretchability and conductivity of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) polymer blends with soft polymers poly(acrylic acid) (PAA) and their application in pressure sensors.
Optimal weighted bilateral filter with dual‐range kernel for Gaussian noise removal
Authors: Wu Geming , Luo Shuqian , Yang Zhi
Published: March 2020

The bilateral filter is a classical technique for edge‐preserving smoothing. It has been widely used as an effective image denoising approach to remove Gaussian noise. The performance of bilateral filtering highly depends on the accuracy of its range distance estimation, which is used for pixel‐neighbourhood similarity measurement. However, in the conventional bilateral filtering approach, estimating the range distance directly from noisy observation results in the degradation of denoising performance. To address this issue, the authors propose a novel bilateral filtering scheme with a dual‐range kernel, which provides a more robust range of distance estimation at various noise levels compared with existing methods. To further improve the denoising performance, they employ a linear model to retrieve the remaining image details from the method noise and add them back to the denoised image by employing an optimal approach based on Stein's unbiased risk estimate. Experiments on standard test images demonstrate that the proposed method outperforms conventional bilateral filter and its major state‐of‐the‐art variants.
Coordination of the in situ payload of Solar Orbiter
Authors: Walsh A. P. , Horbury T. S. , Maksimovic M. , Owen C. J. , Rodríguez-Pacheco J. , Wimmer-Schweingruber R. F. , Zouganelis I. , Anekallu C. , Bonnin X. , Bruno R. , Carrasco Blázquez I. , Cernuda I. , Chust T. , De Groof A. , Espinosa Lara F. , Fazakerley A. N. , Gilbert H. R. , Gómez-Herrero R. , Ho G. C. , Krucker S. , Lepri S. T. , Lewis G. R. , Livi S. , Louarn P. , Müller D. , Nieves-Chinchilla T. , O’Brien H. , Osuna P. , Plasson P. , Raines J. M. , Rouillard A. P. , St Cyr O. C. , Sánchez L. , Soucek J. , Varsani A. , Verscharen D. , Watson C. J. , Watson G. , Williams D. R.
Published: March 2020

Solar Orbiter’s in situ coordination working group met frequently during the development of the mission with the goal of ensuring that its in situ payload has the necessary level of coordination to maximise science return. Here we present the results of that work, namely how the design of each of the in situ instruments (EPD, MAG, RPW, SWA) was guided by the need for coordination, the importance of time synchronisation, and how science operations will be conducted in a coordinated way. We discuss the mechanisms by which instrument sampling schemes are aligned such that complementary measurements will be made simultaneously by different instruments, and how burst modes are scheduled to allow a maximum overlap of burst intervals between the four instruments (telemetry constraints mean different instruments can spend different amounts of time in burst mode). We also explain how onboard autonomy, inter-instrument communication, and selective data downlink will be used to maximise the number of transient events that will be studied using high-resolution modes of all the instruments. Finally, we briefly address coordination between Solar Orbiter’s in situ payload and other missions.
PORTAL: Three-dimensional polarized (sub)millimeter line radiative transfer
Authors: Lankhaar Boy , Vlemmings Wouter
Published: March 2020

Context. Magnetic fields are important to the dynamics of many astrophysical processes and can typically be studied through polarization observations. Polarimetric interferometry capabilities of modern (sub)millimeter telescope facilities have made it possible to obtain detailed velocity resolved maps of molecular line polarization. To properly analyze these for the information they carry regarding the magnetic field, the development of adaptive three-dimensional polarized line radiative transfer models is necessary.

Aims. We aim to develop an easy-to-use program to simulate the polarization maps of molecular and atomic (sub)millimeter lines in magnetized astrophysical regions, such as protostellar disks, circumstellar envelopes, or molecular clouds.

Methods. By considering the local anisotropy of the radiation field as the only alignment mechanism, we can model the alignment of molecular or atomic species inside a regular line radiative transfer simulation by only making use of the converged output of this simulation. Calculations of the aligned molecular or atomic states can subsequently be used to ray trace the polarized maps of the three-dimensional simulation.

Results. We present a three-dimensional radiative transfer code, POlarized Radiative Transfer Adapted to Lines (PORTAL), that can simulate the emergence of polarization in line emission through a magnetic field of arbitrary morphology. Our model can be used in stand-alone mode, assuming LTE excitation, but it is best used when processing the output of regular three-dimensional (nonpolarized) line radiative transfer modeling codes. We present the spectral polarization map of test cases of a collapsing sphere and protoplanetary disk for multiple three-dimensional magnetic field morphologies.
L’intégration des sciences humaines et sociales dans les formations en santé : passer par les arts et le cinéma pour relever les défis
Authors: Vonarx Nicolas
Published: March 2020

Contexte : Parce que les pratiques médicales et de soins et les savoirs qui les soutiennent sont des constructions sociales, parce que les situations de soin comportent des enjeux éthiques, convoquent une relation entre humains et doivent tenir compte des souffrances et du vécu propres aux personnes soignées, il est convenu que les sciences humaines et sociales doivent être intégrées dans les formations des professionnels de la santé. Problématique : Au regard d’une telle réflexion, plusieurs questionnements sont formulés : comment sont-elles intégrées dans des programmes de formation en santé ? À quels défis sont-elles confrontées et quel matériel pédagogique peut-on emprunter pour déplacer des contenus de sciences humaines et sociales vers des disciplines de la santé qui sont animées par certains rapports aux savoirs ? Conclusion : Ce texte reprend ces questions et propose de mobiliser les arts, et notamment le cinéma de fiction, pour véhiculer des contenus théoriques de sciences humaines et sociales auprès d’étudiants en médecine et en soins infirmiers.
Influence ressentie d’un dispositif de formation interprofessionnelle par simulation pour des étudiants infirmiers et des internes de médecine générale
Authors: Le Lan Antony , Allory Emmanuel , Mancheron Pascale , Boudet Hélène , Banatre Agnès , Renaut Pierric
Published: March 2020

Contexte :  Les formations interprofessionnelles en santé utilisant la méthode de la simulation sont actuellement en plein développement. Objectif : Évaluer le ressenti de l’influence sur les pratiques professionnelles d’étudiants infirmiers et d’internes de médecine générale concernant de telles formations. Méthodes : Cette étude qualitative par focus groupes a été réalisée six mois après une formation proposée par l’institut de formation en soins infirmiers et le département de médecine générale de Rennes en mars 2015. Résultats : L’analyse du verbatim a permis de souligner de nombreux apprentissages sur le plan de la collaboration interprofessionnelle. Il a été noté un changement des représentations professionnelles permettant une meilleure communication et un échange de compétences efficace aboutissant à un renforcement de l’identité professionnelle de chacun et une projection vers un statut de professionnel de santé. Conclusion : Cette expérience unique et novatrice reste donc à développer pour en majorer l’impact sur les pratiques professionnelles.
Merging decision-making units with interval data
Authors: Ghobadi Saeid
Published: March 2020

This paper deals with the problem of merging units with interval data. There are two important problems in the merging units. Estimation of the inherited inputs/outputs of the merged unit from merging units is the first problem while the identification of the least and most achievable efficiency targets from the merged unit is the second one. In the imprecise or ambiguous data framework, the inverse DEA concept and linear programming models could be employed to solve the first and second problem, respectively. To identify the required inputs/outputs from merging units, the merged entity is enabled by the proposed method. This provides a predefined efficiency goal. The best and worst attainable efficiency could be determined through the presented models. The developed merging theory is evaluated through a banking sector application.
Rehabilitation seltener Erkrankungen:
Ochronose/Alkaptonurie
Authors: Gehlen Martin , Mahn Karin , Schwarz-Eywill Michael , Gerß Lisa , Siebers-Renelt Ulrike , Önder Nuri , Maier Anna
Published: March 2020

Eine Alkaptonurie ist eine seltene Stoffwechselerkrankung, die zu dem klinischen
Bild der Ochronose führt. Durch einen genetisch terminierten Enzymdefekt
treten bräunliche Pigmentablagerungen in bradytrophen Geweben auf.
Klinisch stehen schwere degenerative Gelenk- und
Wirbelsäulenveränderungen, eine Osteoporose und
Herzklappenvitien im Vordergrund. Dieser Artikel gibt einen Überblick
über klinische Manifestationen und multimodale
Therapiemöglichkeiten im Rahmen einer stationären
Rehabilitation.
Metal-Free Addition of Boronic Acids to Silylnitronates
Authors: El Kaïm Laurent , Kerim Mansour Dolé , Boyode Pakoupati , Garrec Julian
Published: March 2020

We report for the first time a metal-free addition of boronic acids to silylnitronates to afford oxime derivatives through aryl transfer on the carbon nitrogen double bond. A reaction mechanism has been proposed in relation with a DFT study on the key aryl transfer. This arylation process is effective for cycloalkenyl nitro derivatives leading to oximes that may be oxidatively converted into 3-arylisoxazole derivatives.
A Conceptual Framework of Social Communication: Clinical Applications to Pediatric Traumatic Brain Injury
Authors: Wiseman-Hakes Catherine , Kakonge Lisa , Doherty Meghan , Beauchamp Miriam
Published: March 2020

Social communication impairments are common following pediatric traumatic brain injury (TBI) and can lead to social isolation, and poor social outcomes. Social communication has been documented as a persistent area of need in terms of proper assessment and intervention; however, this is not consistently addressed in clinical practice. While there is a body of evidence regarding social communication impairments and pediatric TBI, this area is not yet fully understood and remains underrecognized. To meet this gap, we provide a conceptual framework of social communication from a neurodevelopmental perspective, which can be applied to better understand the social communication impairments associated with pediatric TBI. We propose a general model of social communication with component constructs and consideration of internal factors such as sex and gender. These can inform considerations, clinical applications, and future research in assessment and evidence-based interventions within the domain of social communication.
Piotroski’s FSCORE: international evidence
Authors: Walkshäusl Christian
Published: March 2020

Almost 20 years after its publication, Piotroski’s (J Account Res 38:1–41, 2000) FSCORE, the composite measure of the firm’s fundamental strength remains a strong predictor of subsequent stock returns and future profitability in international markets over the 2000–2018 period. Across developed non-US countries as well as emerging countries, high-FSCORE firms significantly outperform low-FSCORE firms by about 10% per year. Furthermore, FSCORE preserves its return-predictive power in all size segments after controlling for established cross-sectional return determinants, such as firm size, book-to-market, momentum, operating profitability, and investment. The findings are consistent with the view that fundamental information is only gradually incorporated into prices by investors.
Life cycle assessment of hole transport free planar–mesoscopic perovskite solar cells
Authors: Sarialtin Huseyin , Geyer Roland , Zafer Ceylan
Published: March 2020

Organo-metal lead halide perovskite solar cells (PSCs) attract attention due to their low cost and high power conversion efficiency. Some weak points of this technology are short lifetime, instability, and expensive metal electrode deposition. Eliminating the unstable hole transport layer (HTL) and using carbon-based materials as the counter electrode would address both. In this work, we present a cradle-to-gate life cycle assessment of two HTL-free PSC designs, which use solution phase deposition to achieve mesoscopic and planar structures. Environmental impacts of producing 1 m2 PSCs are converted to impacts per kWh electricity generation assuming 5 years of operational lifetime. We find that major impacts come from fluorine doped tin oxide (FTO) glass patterning due to the electricity consumption of FTO patterning and glass cleaning processes. Even though the electricity consumption when manufacturing both PSCs is similar, their different efficiencies make the environmental impacts per kWh of electricity higher for the mesoscopic PSC than for the planar PSC. Energy payback time values of planar PSCs and mesoscopic PSCs are 0.58 and 0.74 years, respectively, and these values are shorter than those of commercial first and second generation solar cells. However, the global warming potential (GWP) values of planar and mesoscopic PSCs are 75 and 94 g CO2-eq/kWh, respectively, and these values are still higher than those of commercial solar cells. To reach the GWP of commercial cells, the operational lifetime would have to be 8 and 10 years for planar and mesoscopic PSCs, respectively.
Identification and characterization of the dominant thermal resistance in lithium-ion batteries using operando 3-omega sensors
Authors: Lubner Sean D. , Kaur Sumanjeet , Fu Yanbao , Battaglia Vince , Prasher Ravi S.
Published: March 2020

Poor thermal transport within lithium-ion batteries fundamentally limits their performance, safety, and lifetime, in spite of external thermal management systems. All prior efforts to understand the origin of batteries' mysteriously high thermal resistance have been confined to ex situ measurements without understanding the impact of battery operation. Here, we develop a frequency-domain technique that employs sensors capable of measuring spatially resolved intrinsic thermal transport properties within a live battery while it is undergoing cycling. Our results reveal that the poor battery thermal transport is due to high thermal contact resistance between the separator and both electrode layers and worsens as a result of formation cycling, degrading total battery thermal transport by up to 70%. We develop a thermal model of these contact resistances to explain their origin. These contacts account for up to 65% of the total thermal resistance inside the battery, leading to far-reaching consequences for the thermal design of batteries. Our technique unlocks new thermal measurement capabilities for future battery research.
Molecular polaritons for controlling chemistry with quantum optics
Authors: Herrera Felipe , Owrutsky Jeffrey
Published: March 2020

This is a tutorial-style introduction to the field of molecular polaritons. We describe the basic physical principles and consequences of strong light–matter coupling common to molecular ensembles embedded in UV–visible or infrared cavities. Using a microscopic quantum electrodynamics formulation, we discuss the competition between the collective cooperative dipolar response of a molecular ensemble and local dynamical processes that molecules typically undergo, including chemical reactions. We highlight some of the observable consequences of this competition between local and collective effects in linear transmission spectroscopy, including the formal equivalence between quantum mechanical theory and the classical transfer matrix method, under specific conditions of molecular density and indistinguishability. We also overview recent experimental and theoretical developments on strong and ultrastrong coupling with electronic and vibrational transitions, with a special focus on cavity-modified chemistry and infrared spectroscopy under vibrational strong coupling. We finally suggest several opportunities for further studies that may lead to novel applications in chemical and electromagnetic sensing, energy conversion, optoelectronics, quantum control, and quantum technology.
Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections
Authors: Oyarte Gálvez Loreto , Fraters Arjan , Offerhaus Herman L. , Versluis Michel , Hunter Ian W. , Fernández Rivas David
Published: March 2020

Illuminating a water solution with a focused continuous wave laser produces a strong local heating of the liquid that leads to the nucleation of bubbles, also known as thermocavitation. During the growth of the bubble, the surrounding liquid is expelled from the constraining microfluidic channel through a nozzle, creating a jet. The characteristics of the resulting liquid jet were imaged using ultra-fast imaging techniques. Here, we provide a phenomenological description of the jet shapes and velocities and compare them with a boundary integral numerical model. We define the parameter regime, varying jet speed, taper geometry, and liquid volume for optimal printing, injection, and spray applications. These results are important for the design of energy-efficient needle-free jet injectors based on microfluidic thermocavitation.
Collisional multispecies drift fluid model
Authors: Poulsen A. , Rasmussen J. Juul , Wiesenberger M. , Naulin V.
Published: March 2020

Transport in the edge and scrape-off layer mediated by turbulent fluctuations is often studied using drift fluid models. In this work, we expand previous work on a two-fluid single ion species drift model to a multi-ion-species model that incorporates collisional interactions between the individual species while conserving energy. The model is simplified into a set of equations that are computationally realizable. This is used to study the dependency of seeded blob propagation on different mixes of deuterium and tritium isotopes in the background and blob, respectively. We find that the background mix is initially the dominant driver that determines propagation, but the blob mix becomes the dominating factor for continued evolution. It is found that the maximum velocity of the blob scales stronger with the initial blob mix than the background mix.
Impact of stalk on directly driven inertial confinement fusion implosions
Authors: Gatu Johnson M. , Adrian P. J. , Anderson K. S. , Appelbe B. D. , Chittenden J. P. , Crilly A. J. , Edgell D. , Forrest C. J. , Frenje J. A. , Glebov V. Yu. , Haines B. M. , Igumenshchev I. , Jacobs-Perkins D. , Janezic R. , Kabadi N. V. , Knauer J. P. , Lahmann B. , Mannion O. M. , Marshall F. J. , Michel T. , Séguin F. H. , Shah R. , Stoeckl C. , Walsh C. A. , Petrasso R. D.
Published: March 2020

Low-mode asymmetries have emerged as one of the primary challenges to achieving high-performing inertial confinement fusion (ICF) implosions. In direct-drive ICF, an important potential seed of such asymmetries is the capsule stalk mount, the impact of which has remained a contentious question. In this paper, we describe the results from an experiment on the OMEGA laser with intentional offsets at varying angles to the capsule stalk mount, which clearly demonstrates the impact of the stalk mount on implosion dynamics. The angle between stalk and offset is found to significantly impact observables. Specifically, a larger directional flow is observed in neutron spectrum measurements when the offset is toward rather than away from the stalk, while an offset at 42° to the stalk gives minimal directional flow but still generates a large flow field in the implosion. No significant directional flow is seen due to stalk only. Time-integrated x-ray images support these flow observations. A trend is also seen in implosion yield, with lower yield obtained for offsets with a smaller angle than with a larger angle toward the stalk. Radiation hydrodynamic simulations using 2D DRACO and 2D/3D Chimera not including the stalk mount and using 2D xRAGE including the stalk mount are brought to bear on the data. The yield trend, the minimal directional flow with stalk only, and the larger flow enhancement observed with the offset toward the stalk are all reproduced in the xRAGE simulations. The results strongly indicate that the stalk impact must be considered and mitigated to achieve high-performing implosions.
Point defects in Ga2O3
Authors: McCluskey Matthew D.
Published: March 2020

In the field of high-power electronics, gallium oxide (Ga2O3) is attracting attention due to its wide bandgap and ability to be doped n-type. Point defects, including vacancies, impurities, and dopants, play important roles in optimizing device performance. This tutorial discusses the fundamental properties of point defects in monoclinic β-Ga2O3 and the methods employed to study them. Oxygen vacancies are deep donors that do not cause n-type conductivity but may compensate acceptors. Gallium vacancies are deep acceptors that can be partially passivated by hydrogen. Substitutional magnesium is a promising acceptor that produces a semi-insulating material and also forms a complex with hydrogen. Calcium and iron also have deep acceptor levels. Iridium deep donors are introduced into crystals grown from a melt in an Ir crucible. Other defects are introduced by irradiation with energetic particles such as neutrons or protons. In addition to altering the electronic properties, defects give rise to UV/visible emission bands in photoluminescence and cathodoluminescence spectra.
Thermally modulated hydrogenation in FexPd1−x alloy films: Temperature-driven peculiar variation of magnetism
Authors: Chang Po-Chun , Chuang Tzu-Hung , Wei Der-Hsin , Lin Wen-Chin
Published: March 2020

The sensitive hydrogen effect on spintronic materials has been recently demonstrated to have high application potential. However, the correlation between hydrogen pressure (PH2), temperature, and magnetic properties still remains unclear. In this study, the magnetic moment of Fe in an Fe–Pd alloy thin film was increased through hydrogen absorption, as evidenced by the enhanced x-ray magnetic circular dichroism signal of Fe. Hydrogen absorption and desorption hysteresis loops in the magnetic coercivity Hc-PH2 diagram revealed that most hydrogen was absorbed when PH2 was above 10 mbar and desorbed when PH2 was approximately 10–6 mbar. The hydrogenation effect on the magnetism of an Fe–Pd alloy film was eliminated at an annealing temperature of 360 K without considerable hydrogen desorption. The annealing-driven cyclic enhancement of Hc was demonstrated because of the competition between thermal activation and H bonding. These results clearly reveal the critical temperature dependence and provide applicable knowledge of the hydrogenation effect on magnetic Pd-alloys.
The water/ceria(111) interface: Computational overview and new structures
Authors: Röckert Andreas , Kullgren Jolla , Broqvist Peter , Alwan Seif , Hermansson Kersti
Published: March 2020

Thin film structures of water on the CeO2(111) surface for coverages between 0.5 and 2.0 water monolayers have been optimized and analyzed using density functional theory (optPBE-vdW functional). We present a new 1.0 ML structure that is both the lowest in energy published and features a hydrogen-bond network extending the surface in one-dimension, contrary to what has been found in the literature, and contrary to what has been expected due to the large bulk ceria cell dimension. The adsorption energies for the monolayer and multilayered water structures agree well with experimental temperature programmed desorption results from the literature, and we discuss the stability window of CeO2(111) surfaces covered with 0.5–2.0 ML of water.
The effects of intersystem and reverse intersystem crossing on the optical limiting properties of C60
Authors: Veisi Mohadeseh , Kazemi Seyedeh Hamideh , Mahmoudi Mohammad
Published: March 2020

By presenting a theoretical steady-state rate equation analysis, we demonstrate an efficient optical power limiting in a fullerene system, which can be attributed to a reverse saturable absorption mechanism. The limiting behavior, characterized by means of the sample’s transmittance, is explained via the population redistribution among singlet and triplet levels. In addition, the effects of intersystem crossing and reverse intersystem crossing rates on the limiting behavior are investigated. Our numerical results show how these rates alter the optical limiting performance; indeed, the intersystem crossing has a constructive role in decreasing the optical limiting threshold. In addition, a theoretical investigation of the z-scan technique is employed to further characterize the power limiting properties.
Reducing frequency drift caused by light shift in coherent population trapping-based low-power atomic clocks
Authors: Yanagimachi Shinya , Harasaka Kazuhiro , Suzuki Ryoichiro , Suzuki Mitsuru , Goka Shigeyoshi
Published: March 2020

We propose a model to reduce the influence that the light-shift induced frequency drift has on the long-term stability of coherent population trapping (CPT)-based low-power atomic clocks. We experimentally validated the proposed model using the chip-scale atomic clock architecture. The model considers both the drift of the dc-bias current to compensate for the wavelength aging of the vertical-cavity surface-emitting laser (VCSEL) and the variation in the modulation index of the light field generated by the VCSEL. We investigated the dc-bias-current-dependency of the frequency drift in an atomic clock module both theoretically and experimentally, confirming that the frequency drift can change as a function of the VCSEL basic parameters. When the atomic clock module was operated over a period of five months at the dc-bias current affording a zero-crossing of the clock frequency drift, the Allan standard deviation and clock frequency drift for long-term stability were 8.0×10−12 for averaging times of 4×106 s and 2.4×10−13/day, respectively. Our approach is promising to improve the long-term stability of CPT-based low-power atomic clocks.
High-throughput, combinatorial synthesis of multimetallic nanoclusters
Authors: Yao Yonggang , Huang Zhennan , Li Tangyuan , Wang Hang , Liu Yifan , Stein Helge S. , Mao Yimin , Gao Jinlong , Jiao Miaolun , Dong Qi , Dai Jiaqi , Xie Pengfei , Xie Hua , Lacey Steven D. , Takeuchi Ichiro , Gregoire John M. , Jiang Rongzhong , Wang Chao , Taylor Andre D. , Shahbazian-Yassar Reza , Hu Liangbing
Published: March 2020

Significance

Multielement nanomaterials hold great promise for various applications due to their widely tunable surface chemistry, yet it remains challenging to efficiently study this multidimensional space. Conventional approaches are typically slow and depend on serendipity, while a robust and general synthesis is still lacking among increasingly complex compositions. We report a high-throughput technique for combinatorial compositional design (formulation in solution phases) and rapid synthesis (within seconds) of ultrafine multimetallic nanoclusters with a homogeneous alloy structure. We synthesized and screened the PtPdRhRuIrFeCoNi compositional space using scanning droplet cell electrochemistry, with two promising catalysts quickly identified and further verified in a rotating disk setup. The reported high-throughput approach establishes a facile and reliable pipeline to significantly accelerate material discovery in multimetallic nanomaterials.
Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation
Authors: Marreiros Rita , Müller-Schiffmann Andreas , Trossbach Svenja V. , Prikulis Ingrid , Hänsch Sebastian , Weidtkamp-Peters Stefanie , Moreira Ana Raquel , Sahu Shriya , Soloviev Irina , Selvarajah Suganya , Lingappa Vishwanath R. , Korth Carsten
Published: March 2020

Significance

Synucleinopathies such as Parkinson’s disease feature deposition of misfolded α-synuclein. It is likely that cellular proteostasis compensates for misfolded α-synuclein to some extent, but, once exhausted, α-synuclein can form seeds for a prion-like spread in the brain. Here, we demonstrate that, in human dopaminergic neurons and in mouse brain, H1N1 influenza virus induces aggregation of α-synuclein by blocking protein degradation pathways. Following intranasal instillation, H1N1 spreading along the olfactory route into brain areas mimics α-synuclein deposits in synucleinopathies. H1N1 may therefore be considered a risk factor for synucleinopathies that could potentially be minimized by regular vaccination. On the contrary, H1N1 tropism for olfactory epithelium suggests that live attenuated virus vaccines should be investigated for possible long-term effects on protein misfolding.
Spatiotemporal gating of SIRT1 functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia
Authors: Chattopadhyay Tandrika , Maniyadath Babukrishna , Bagul Hema P. , Chakraborty Arindam , Shukla Namrata , Budnar Srikanth , Rajendran Abinaya , Shukla Arushi , Kamat Siddhesh S. , Kolthur-Seetharam Ullas
Published: March 2020

Significance

Emerging literature indicates that, besides circadian inputs, fed–fast cycles are vital for maintaining physiological homeostasis. While several studies have highlighted the importance of feeding and state-specific molecular signatures, information regarding mechanisms that bring about efficient fed–fast–refed transitions is sparse. Here we show how a glucose-derived modification (glycosylation) of SIRT1, a master regulator of transcription and insulin signaling, regulates this metabolic switch in the liver by restricting SIRT1 functions during fasted-to-refed transition. SIRT1 glycosylation orchestrates molecular interactions to suppress fasting genes, derepress fed genes, and activate insulin signaling upon refeeding. We show that aberrant SIRT1 glycosylation causes hepatic dysfunctions resulting in a diabetes-like state and is also associated with aging and obesity.