bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 1 from Characterization and Clinical Relevance of ALDHbright Populations in Prostate Cancer
Authors: Le Magnen Clémentine , Bubendorf Lukas , Rentsch Cyrill A. , Mengus Chantal , Gsponer Joel , Zellweger Tobias , Rieken Malte , Thalmann George N. , Cecchini Marco G. , Germann Markus , Bachmann Alexander , Wyler Stephen , Heberer Michael , Spagnoli Giulio C.
Published: April 2023

PDF file, 39K, Characteristics of PCa patients.
Supplementary Figure 2 from Characterization and Clinical Relevance of ALDHbright Populations in Prostate Cancer
Authors: Le Magnen Clémentine , Bubendorf Lukas , Rentsch Cyrill A. , Mengus Chantal , Gsponer Joel , Zellweger Tobias , Rieken Malte , Thalmann George N. , Cecchini Marco G. , Germann Markus , Bachmann Alexander , Wyler Stephen , Heberer Michael , Spagnoli Giulio C.
Published: April 2023

PDF file, 3314K, Representative IHC analysis of ALDH1A1 expression in large tissues prostate sections.
Supplementary Figure 1 from Characterization and Clinical Relevance of ALDHbright Populations in Prostate Cancer
Authors: Le Magnen Clémentine , Bubendorf Lukas , Rentsch Cyrill A. , Mengus Chantal , Gsponer Joel , Zellweger Tobias , Rieken Malte , Thalmann George N. , Cecchini Marco G. , Germann Markus , Bachmann Alexander , Wyler Stephen , Heberer Michael , Spagnoli Giulio C.
Published: April 2023

PDF file, 1824K, Differential expression and localization of ALDH1A1 and ALDH7A1 proteins in BPH.
Supplementary Figure S7 from GKN1–miR-185–DNMT1 Axis Suppresses Gastric Carcinogenesis through Regulation of Epigenetic Alteration and Cell Cycle
Authors: Yoon Jung Hwan , Choi Yoo Jin , Choi Won Suk , Ashktorab Hassan , Smoot Duane T. , Nam Suk Woo , Lee Jung Young , Park Won Sang
Published: April 2023

Supplementary Figure S7 - PDF file 37K, Effects of miR-185 on GKN1 induced inhibited cell growth
Supplementary Table 2 from A Phase 1, Dose-Escalation, Pharmacokinetic and Pharmacodynamic Study of BIIB021 Administered Orally in Patients with Advanced Solid Tumors
Authors: Saif Muhammad Wasif , Takimoto Chris , Mita Monica , Banerji Udai , Lamanna Nicole , Castro Januario , O'Brien Susan , Stogard Christopher , Von Hoff Daniel
Published: April 2023

PDF file 62K, Clinical Activity Observed with BIIB021 in CLL
Supplementary Figure Legend from Targeting the Phosphoinositide 3-Kinase p110-α Isoform Impairs Cell Proliferation, Survival, and Tumor Growth in Small Cell Lung Cancer
Authors: Wojtalla Anna , Fischer Barbara , Kotelevets Nataliya , Mauri Francesco A. , Sobek Jens , Rehrauer Hubert , Wotzkow Carlos , Tschan Mario P. , Seckl Michael J. , Zangemeister-Wittke Uwe , Arcaro Alexandre
Published: April 2023

PDF file - 78K
Supplementary Table 4 from Surveillance of the Tumor Mutanome by T Cells during Progression from Primary to Recurrent Ovarian Cancer
Authors: Wick Darin A. , Webb John R. , Nielsen Julie S. , Martin Spencer D. , Kroeger David R. , Milne Katy , Castellarin Mauro , Twumasi-Boateng Kwame , Watson Peter H. , Holt Rob A. , Nelson Brad H.
Published: April 2023

PDF file - 46K, Patient MHC class I alleles.
Supplementary Table 3 from Surveillance of the Tumor Mutanome by T Cells during Progression from Primary to Recurrent Ovarian Cancer
Authors: Wick Darin A. , Webb John R. , Nielsen Julie S. , Martin Spencer D. , Kroeger David R. , Milne Katy , Castellarin Mauro , Twumasi-Boateng Kwame , Watson Peter H. , Holt Rob A. , Nelson Brad H.
Published: April 2023

PDF file - 72K, Tested minimal peptides and corresponding MHC binding scores for Patient 3.
Supplementary Table 6 from Elevated TNFR1 and Serotonin in Bone Metastasis Are Correlated with Poor Survival following Bone Metastasis Diagnosis for Both Carcinoma and Sarcoma Primary Tumors
Authors: Chiechi Antonella , Novello Chiara , Magagnoli Giovanna , Petricoin Emanuel F. , Deng Jianghong , Benassi Maria S. , Picci Piero , Vaisman Iosif , Espina Virginia , Liotta Lance A.
Published: April 2023

XLSX file - 351K, Spearman's Rho correlation analysis results for the short-survivor group, using RPMA data.
Supplementary Table 3 from Elevated TNFR1 and Serotonin in Bone Metastasis Are Correlated with Poor Survival following Bone Metastasis Diagnosis for Both Carcinoma and Sarcoma Primary Tumors
Authors: Chiechi Antonella , Novello Chiara , Magagnoli Giovanna , Petricoin Emanuel F. , Deng Jianghong , Benassi Maria S. , Picci Piero , Vaisman Iosif , Espina Virginia , Liotta Lance A.
Published: April 2023

XLSX file - 108K, Primary tumor group statistics.
Supplementary Table 1 from PIK3CA Mutation Is Associated with a Favorable Prognosis among Patients with Curatively Resected Esophageal Squamous Cell Carcinoma
Authors: Shigaki Hironobu , Baba Yoshifumi , Watanabe Masayuki , Murata Asuka , Ishimoto Takatsugu , Iwatsuki Masaaki , Iwagami Shiro , Nosho Katsuhiko , Baba Hideo
Published: April 2023

PDF File - 44K, PIK3CA mutations in ESCC.
Supplementary Figure 1 from Elevated TNFR1 and Serotonin in Bone Metastasis Are Correlated with Poor Survival following Bone Metastasis Diagnosis for Both Carcinoma and Sarcoma Primary Tumors
Authors: Chiechi Antonella , Novello Chiara , Magagnoli Giovanna , Petricoin Emanuel F. , Deng Jianghong , Benassi Maria S. , Picci Piero , Vaisman Iosif , Espina Virginia , Liotta Lance A.
Published: April 2023

PDF file - 3431K, Anti-TNFR1 antibody validation by western blot. Area Under the Curve (AUC) value changes with the data set size in the machine learning model. Anti-Serotonin antibody validation by competition assay using reverse phase protein microarray (RPMA).
Supplementary Figures 1 - 7 from Plasma MicroRNAs as Novel Biomarkers for Endometriosis and Endometriosis-Associated Ovarian Cancer
Authors: Suryawanshi Swati , Vlad Anda M. , Lin Hui-Min , Mantia-Smaldone Gina , Laskey Robin , Lee MinJae , Lin Yan , Donnellan Nicole , Klein-Patel Marcia , Lee Ted , Mansuria Suketu , Elishaev Esther , Budiu Raluca , Edwards Robert P. , Huang Xin
Published: April 2023

PDF file - 488K, Supplementary Figure 1: Experimental design. Supplementary Figure 2. Reliability of RNA extraction and reproducibility of RTqPCR techniques. Supplementary Figure 3. Reliability of RT-qPCR assays. Supplementary Figure 4. miR-132 demonstrates consistent CT values (ranging from 27 to 29.5.) across all categories of plasma samples (healthy 0=Normal Healthy Endo1=mEnedtoriosis 2 = SSOerCous 3E=EAAOOCC controls, n=20; endometriosis, n=33; EAOC, n=14; and SOC, n=21), and was used for normalization of RT-qPCR results in this study. Supplementary Figure 5. Unsupervised hierarchical clustering analysis of samples based on the 23-miRNA expression profiles. Supplementary Figure 6. Box plots of top three differentially expressed miRNAs in pair-wise comparisons. Supplementary Figure 7. Lack of correlation for miRNA expression between matching tumor tissue and plasma samples from five tumor-bearing LSLKrasG12D/+/ Ptenloxp/loxp mice.
Supplementary Table 2 from Interleukin-17A Modulates Circulating Tumor Cells in Tumor Draining Vein of Colorectal Cancers and Affects Metastases
Authors: Tseng Ju-Yu , Yang Chih-Yung , Liang Shu-Ching , Liu Ren-Shyan , Yang Shung-Haur , Lin Jen-Kou , Chen Yuh-Min , Wu Yu-Chung , Jiang Jeng-Kai , Lin Chi-Hung
Published: April 2023

PDF file - 65KB, Pretherapy serum levels of cytokines in patients with and without recurrence.
Supplementary Figure 2 from AXL Is a Key Regulator of Inherent and Chemotherapy-Induced Invasion and Predicts a Poor Clinical Outcome in Early-Stage Colon Cancer
Authors: Dunne Philip D. , McArt Darragh G. , Blayney Jaine K. , Kalimutho Murugan , Greer Samanda , Wang Tingting , Srivastava Supriya , Ong Chee Wee , Arthur Ken , Loughrey Maurice , Redmond Keara , Longley Daniel B. , Salto-Tellez Manuel , Johnston Patrick G. , Van Schaeybroeck Sandra
Published: April 2023

PDF file - 213K, Migration, proliferation rates and RTK profiling of HCT116 parental and invasive cells.
Supplementary Table 1 from Impact of Bioinformatic Procedures in the Development and Translation of High-Throughput Molecular Classifiers in Oncology
Authors: Ferté Charles , Trister Andrew D. , Huang Erich , Bot Brian M. , Guinney Justin , Commo Frederic , Sieberts Solveig , André Fabrice , Besse Benjamin , Soria Jean-Charles , Friend Stephen H.
Published: April 2023

PDF file - 58K, Description of all the published studies related to NSCLC gene expression data with prognostic information and their actual availability as raw data.
Supplementary Table 3 from Synergistic Interaction between the HDAC Inhibitor, MPT0E028, and Sorafenib in Liver Cancer Cells In Vitro and In Vivo
Authors: Chen Chun-Han , Chen Mei-Chuan , Wang Jing-Chi , Tsai An-Chi , Chen Ching-Shih , Liou Jing-Ping , Pan Shiow-Lin , Teng Che-Ming
Published: April 2023

PDF file - 72KB, Combination index (CI) values of sorafenib in combination with MPT0E028 or vorinostat in liver cancer cells.
Supplementary Table 2 from Synergistic Interaction between the HDAC Inhibitor, MPT0E028, and Sorafenib in Liver Cancer Cells In Vitro and In Vivo
Authors: Chen Chun-Han , Chen Mei-Chuan , Wang Jing-Chi , Tsai An-Chi , Chen Ching-Shih , Liou Jing-Ping , Pan Shiow-Lin , Teng Che-Ming
Published: April 2023

PDF file - 51KB, Differential cytotoxic effects of sorafenib, MPT0E028 and vorinostat on different liver cancer cell lines.
Supplementary Figure Legends from Synergistic Interaction between the HDAC Inhibitor, MPT0E028, and Sorafenib in Liver Cancer Cells In Vitro and In Vivo
Authors: Chen Chun-Han , Chen Mei-Chuan , Wang Jing-Chi , Tsai An-Chi , Chen Ching-Shih , Liou Jing-Ping , Pan Shiow-Lin , Teng Che-Ming
Published: April 2023

PDF file - 90KB
Supplementary Methods, Figures 1 - 4, Table 1 from Importance of EGFR/ERCC1 Interaction Following Radiation-Induced DNA Damage
Authors: Liccardi Gianmaria , Hartley John A. , Hochhauser Daniel
Published: April 2023

PDF file - 1749KB, Supplementary Figure 1. Ingenuity pathway analysis Supplementary Figure 2. A549 AND A431 cells were treated with 4 Gy IR. Supplementary Figure 3. M059K, M059J, were treated with 4 Gy of IR and then fixed with 4 percent paraformaldehyde (PFA) 20 minutes following treatment. Supplementary Figure 4. EGFR/ERCC1 effect on survival. BON1 cells were transfected with non-targeting, ERCC1, EGFR or EGFR/ERCC1 SiRNA. Supplementary Table 1. List of EGFR interactors involved in DNA repair identified by mass spectrometry.
Supplementary Figure 3 from Personalized Chemotherapy Profiling Using Cancer Cell Lines from Selectable Mice
Authors: Kamiyama Hirohiko , Rauenzahn Sherri , Shim Joong Sup , Karikari Collins A. , Feldmann Georg , Hua Li , Kamiyama Mihoko , Schuler F. William , Lin Ming-Tseh , Beaty Robert M. , Karanam Balasubramanyam , Liang Hong , Mullendore Michael E. , Mo Guanglan , Hidalgo Manuel , Jaffee Elizabeth , Hruban Ralph H. , Jinnah H.A. , Roden Richard B.S. , Jimeno Antonio , Liu Jun O. , Maitra Anirban , Eshleman James R.
Published: April 2023

PDF file - 219K, Genotyping assays.
Supplementary Tables S1-5 from Resistance to CDK2 Inhibitors Is Associated with Selection of Polyploid Cells in CCNE1-Amplified Ovarian Cancer
Authors: Etemadmoghadam Dariush , Au-Yeung George , Wall Meaghan , Mitchell Chris , Kansara Maya , Loehrer Elizabeth , Batzios Crisoula , George Joshy , Ftouni Sarah , Weir Barbara A. , Carter Scott , Gresshoff Irma , Mileshkin Linda , Rischin Danny , Hahn William C. , Waring Paul M. , Getz Gad , Cullinane Carleen , Campbell Lynda J. , Bowtell David D.
Published: April 2023

Supplementary Tables S1-5 - PDF filr 185K, Supplementary Table S1: Essentiality of CDKs in CCNE1 amplified cell lines; Supplementary Table S2: GeneGo gene expression pathways enriched in PHA-533533 resistant cell lines; Supplementary Table S3: Copy number changes identified by SNP microarray in PHA-533533 resistant cell lines; Supplementary Table S4: Gene Set Enrichment Analysis (GSEA) of positional gene sets enriched in amplified or deleted genes specific to PHA-533533 resistant cells; Supplementary Table S5: OVCAR-3 cell line and derivative resistant line karyotypes
Supplementary Figure 3 from First-in-Human Phase I Trial of Two Schedules of OSI-930, a Novel Multikinase Inhibitor, Incorporating Translational Proof-of-Mechanism Studies
Authors: Yap Timothy A. , Arkenau Hendrik-Tobias , Camidge D. Ross , George Suzanne , Serkova Natalie J. , Gwyther Stephen J. , Spratlin Jennifer L. , Lal Rohit , Spicer James , Desouza Nandita M. , Leach Martin O. , Chick Jon , Poondru Srinivasu , Boinpally Ramesh , Gedrich Richard , Brock Katie , Stephens Andrew , Eckhardt S. Gail , Kaye Stan B. , Demetri George , Scurr Michelle
Published: April 2023

PDF file - 47K, Association of sVEGR2 changes at the end of the first dosing cycle and patient response in the 500mg BID expansion cohort
Supplementary Methods from Resistance to CDK2 Inhibitors Is Associated with Selection of Polyploid Cells in CCNE1-Amplified Ovarian Cancer
Authors: Etemadmoghadam Dariush , Au-Yeung George , Wall Meaghan , Mitchell Chris , Kansara Maya , Loehrer Elizabeth , Batzios Crisoula , George Joshy , Ftouni Sarah , Weir Barbara A. , Carter Scott , Gresshoff Irma , Mileshkin Linda , Rischin Danny , Hahn William C. , Waring Paul M. , Getz Gad , Cullinane Carleen , Campbell Lynda J. , Bowtell David D.
Published: April 2023

Supplementary Methods - PDF file 70K, CDK2 sequencing methods and primer sequences
Supplementary Information from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential
Authors: Qiu Yunping , Cai Guoxiang , Zhou Bingsen , Li Dan , Zhao Aihua , Xie Guoxiang , Li Houkai , Cai Sanjun , Xie Dong , Huang Changzhi , Ge Weiting , Zhou Zhanxiang , Xu Lisa X. , Jia Weiping , Zheng Shu , Yen Yun , Jia Wei
Published: April 2023

PDF file 119K, This file includes supplementary text and figure legends for supporting figures
Supplementary Methods and Legends from The Mechanism of DAB2IP in Chemoresistance of Prostate Cancer Cells
Authors: Wu Kaijie , Xie Daxing , Zou Yonglong , Zhang Tingting , Pong Rey-Chen , Xiao Guanghua , Fazli Ladan , Gleave Martin , He Dalin , Boothman David A. , Hsieh Jer-Tsong
Published: April 2023

Supplementary Methods and Legends - PDF file 114K, All the supplementary legends and methods
Supplementary Figure Legend from Contribution of Abcc4-Mediated Gastric Transport to the Absorption and Efficacy of Dasatinib
Authors: Furmanski Brian D. , Hu Shuiying , Fujita Ken-ichi , Li Lie , Gibson Alice A. , Janke Laura J. , Williams Richard T. , Schuetz John D. , Sparreboom Alex , Baker Sharyn D.
Published: April 2023

PDF file - 81K
Supplementary Figure 5 from Contribution of Abcc4-Mediated Gastric Transport to the Absorption and Efficacy of Dasatinib
Authors: Furmanski Brian D. , Hu Shuiying , Fujita Ken-ichi , Li Lie , Gibson Alice A. , Janke Laura J. , Williams Richard T. , Schuetz John D. , Sparreboom Alex , Baker Sharyn D.
Published: April 2023

PDF file - 295K, In vitro transport and activity of dasatinib against p185(BCR-ABL)-expressing Arf(-/-) leukemia initiating pre-B cells (LIC).
Supplementary Figure 2 from Contribution of Abcc4-Mediated Gastric Transport to the Absorption and Efficacy of Dasatinib
Authors: Furmanski Brian D. , Hu Shuiying , Fujita Ken-ichi , Li Lie , Gibson Alice A. , Janke Laura J. , Williams Richard T. , Schuetz John D. , Sparreboom Alex , Baker Sharyn D.
Published: April 2023

PDF file - 351K, Influence of reduced glutathione (GSH) and ABCC3 function on dasatinib transport.
Supplementary Figure 1 from Phase I Dendritic Cell p53 Peptide Vaccine for Head and Neck Cancer
Authors: Schuler Patrick J. , Harasymczuk Malgorzata , Visus Carmen , DeLeo Albert , Trivedi Sumita , Lei Yu , Argiris Athanassios , Gooding William , Butterfield Lisa H. , Whiteside Theresa L. , Ferris Robert L.
Published: April 2023

PDF file - 167KB, Study patients with advances HNSCC were assigned to three different treatment arms. 'Arm 1' was vaccinated with dendritic cells (DC) loaded with p53-specific peptides (class I) for sequences 149-157 (modified T150L) and 264-272 (modified F270W). In treatment 'arm 2' DC were additionally loaded with tetanus peptide (class II). In treatment 'arm 3' DC were additionally loaded with p53-specific peptides (class II) for sequence 110-124.
Supplementary Table S1 from Phase I Safety, Pharmacokinetic and Pharmacodynamic Evaluation of the Vascular Disrupting Agent Ombrabulin (AVE8062) in Patients with Advanced Solid Tumors
Authors: Sessa Cristiana , Lorusso Patricia , Tolcher Anthony , Farace Françoise , Lassau Nathalie , Delmonte Angelo , Braghetti Antonio , Bahleda Rastislav , Cohen Patrick , Hospitel Marie , Veyrat-Follet Christine , Soria Jean-Charles
Published: April 2023

Supplementary Table S1 - PDF file 52K, Best overall tumor response (RECIST)
Supplementary Figure Legend from Monoclonal Gammopathy of Undetermined Significance and Smoldering Multiple Myeloma: A Review of the Current Understanding of Epidemiology, Biology, Risk Stratification, and Management of Myeloma Precursor Disease
Authors: Agarwal Amit , Ghobrial Irene M.
Published: April 2023

PDF file - 31K
Supplementary Fig. S1 from Phase I Safety, Pharmacokinetic and Pharmacodynamic Evaluation of the Vascular Disrupting Agent Ombrabulin (AVE8062) in Patients with Advanced Solid Tumors
Authors: Sessa Cristiana , Lorusso Patricia , Tolcher Anthony , Farace Françoise , Lassau Nathalie , Delmonte Angelo , Braghetti Antonio , Bahleda Rastislav , Cohen Patrick , Hospitel Marie , Veyrat-Follet Christine , Soria Jean-Charles
Published: April 2023

Supplementary Fig. S1 - PDF file 83K, Time profiles for estimated change relative to baseline in (A) heart rate and (B) Fridericia-corrected QT interval
Supplementary Table 1 from Genes Upregulated in Prostate Cancer Reactive Stroma Promote Prostate Cancer Progression In Vivo
Authors: Dakhova Olga , Rowley David , Ittmann Michael
Published: April 2023

PDF file - 49K, Primers used.
Supplementary Figures 1 - 4, Tables 1 - 2 from A Novel HLA-A*0201 Restricted Peptide Derived from Cathepsin G Is an Effective Immunotherapeutic Target in Acute Myeloid Leukemia
Authors: Zhang Mao , Sukhumalchandra Pariya , Enyenihi Atim A. , St. John Lisa S. , Hunsucker Sally A. , Mittendorf Elizabeth A. , Sergeeva Anna , Ruisaard Kathryn , Al-Atrache Zein , Ropp Patricia A. , Jakher Haroon , Rodriguez-Cruz Tania , Lizee Gregory , Clise-Dwyer Karen , Lu Sijie , Molldrem Jeffrey J. , Glish Gary L. , Armistead Paul M. , Alatrash Gheath
Published: April 2023

PDF file - 706k, Figure S1. CG is ubiquitinated in AML. Figure S2. CG1 is a naturally processed epitope that is eluted from leukemia cell surface. Figure S3. CG expression by each of the AML samples used in the cytotoxicity assays. Figure S4. Gating strategy used to determine CG1-CTL frequency in AML patient blood. Supplementary Table S1. Characteristics of cathepsin G-derived peptides with highest binding affinity to HLA-A*0201 Supplementary Table S2. AML samples used in determining cathepsin G expression
Supplementary Figure Legend from Caspase-Independent Cell Death Is Involved in the Negative Effect of EGF Receptor Inhibitors on Cisplatin in Non–Small Cell Lung Cancer Cells
Authors: Yamaguchi Hirohito , Hsu Jennifer L. , Chen Chun-Te , Wang Ying-Nai , Hsu Ming-Chuan , Chang Shih-Shin , Du Yi , Ko How-Wen , Herbst Roy , Hung Mien-Chie
Published: April 2023

PDF file - 113K
Supplementary Figure 7 from Caspase-Independent Cell Death Is Involved in the Negative Effect of EGF Receptor Inhibitors on Cisplatin in Non–Small Cell Lung Cancer Cells
Authors: Yamaguchi Hirohito , Hsu Jennifer L. , Chen Chun-Te , Wang Ying-Nai , Hsu Ming-Chuan , Chang Shih-Shin , Du Yi , Ko How-Wen , Herbst Roy , Hung Mien-Chie
Published: April 2023

PDF file - 45K, The effects of NAC on cisplain-induced caspase activation
Supplementary Figure S1 from Improved Differentiation of Benign and Malignant Breast Tumors with Multiparametric 18Fluorodeoxyglucose Positron Emission Tomography Magnetic Resonance Imaging: A Feasibility Study
Authors: Pinker Katja , Bogner Wolfgang , Baltzer Pascal , Karanikas Georgios , Magometschnigg Heinrich , Brader Peter , Gruber Stephan , Bickel Hubert , Dubsky Peter , Bago-Horvath Zsuzsanna , Bartsch Rupert , Weber Michael , Trattnig Siegfried , Helbich Thomas H.
Published: April 2023

Invasive ductal carcinoma G3 in a 67-year-old woman, retroareolar in the right breast. (A) The indistinct, partly spiculated, irregular mass lesion demonstrates (B) heterogeneous initial strong enhancement followed by a wash-out, and was classified as BI-RADS{copyright, serif} 5 (suspicious finding) by DCE-MRI of the breast. (C) On DWI, the mass lesion is bright, and (D) the ADC values (0.77 Ã—10-3 mm2/s) are below the threshold for malignancy.
Supplementary Figure Legends from A Novel Aldehyde Dehydrogenase-3 Activator (Alda-89) Protects Submandibular Gland Function from Irradiation without Accelerating Tumor Growth
Authors: Xiao Nan , Cao Hongbin , Chen Che-Hong , Kong Christina S. , Ali Rehan , Chan Cato , Sirjani Davud , Graves Edward , Koong Albert , Giaccia Amato , Mochly-Rosen Daria , Le Quynh-Thu
Published: April 2023

PDF file, 39K.
Supplementary Figure 2 from Caspase-Independent Cell Death Is Involved in the Negative Effect of EGF Receptor Inhibitors on Cisplatin in Non–Small Cell Lung Cancer Cells
Authors: Yamaguchi Hirohito , Hsu Jennifer L. , Chen Chun-Te , Wang Ying-Nai , Hsu Ming-Chuan , Chang Shih-Shin , Du Yi , Ko How-Wen , Herbst Roy , Hung Mien-Chie
Published: April 2023

PDF file - 298K, Caspase-independent cell death in H1299 cells
Supplementary Fig. 7B from Regulation of Cell Proliferation and Migration by Keratin19-Induced Nuclear Import of Early Growth Response-1 in Breast Cancer Cells
Authors: Ju Ji-hyun , Yang Wonseok , Lee Kyung-min , Oh Sunhwa , Nam KeeSoo , Shim Sarah , Shin Soon Young , Gye Myung Chan , Chu In-Sun , Shin Incheol
Published: April 2023

Supplementary Fig. 7B - PDF file 67K, Correlation between KRT19 and HER2 expression in breast cancer patient samples
Supplementary Fig. 2 from Regulation of Cell Proliferation and Migration by Keratin19-Induced Nuclear Import of Early Growth Response-1 in Breast Cancer Cells
Authors: Ju Ji-hyun , Yang Wonseok , Lee Kyung-min , Oh Sunhwa , Nam KeeSoo , Shim Sarah , Shin Soon Young , Gye Myung Chan , Chu In-Sun , Shin Incheol
Published: April 2023

Supplementary Fig. 2 - PDF file 2822K, KRT19 inhibition up-regulates colony formation, cell migration and invasion
Supplementary Methods from Identification of Multiple Mechanisms of Resistance to Vemurafenib in a Patient with BRAFV600E-Mutated Cutaneous Melanoma Successfully Rechallenged after Progression
Authors: Romano Emanuela , Pradervand Sylvain , Paillusson Alexandra , Weber Johann , Harshman Keith , Muehlethaler Katja , Speiser Daniel , Peters Solange , Rimoldi Donata , Michielin Olivier
Published: April 2023

Supplementary Methods - PDF file 55K, This file contains Supplementary Methods.
Supplementary Figures from Identification of Multiple Mechanisms of Resistance to Vemurafenib in a Patient with BRAFV600E-Mutated Cutaneous Melanoma Successfully Rechallenged after Progression
Authors: Romano Emanuela , Pradervand Sylvain , Paillusson Alexandra , Weber Johann , Harshman Keith , Muehlethaler Katja , Speiser Daniel , Peters Solange , Rimoldi Donata , Michielin Olivier
Published: April 2023

Supplementary Figures - PDF file 828K, This file contains Supplementary Figures: This file contains supplementary Figures: Suppl. Figure 1. CT scan at baseline and after 3 months since first introduction of vemurafenib. Suppl. Figure 2. Copy number alteration (CNA) from whole exome sequencing data. Suppl. Figure 3. B Allele Frequencies (BAF) of germline heterozygous SNPs located in CNA regions. Suppl. Figure 4. Sensitivity of a PV1-derived cell line to BRAF and MEK inhibitors. Suppl. Figure 5. Sanger sequencing of PI3KCA and NRAS amplified cDNA fragments from single cell clones isolated from the T1407A short-time culture (PV1 metastasis). Suppl. Figure 6. Sensitivity of PIK3CA mutated clones to combinations of MEK/PI3K and RAF/MEK inhibitors. Suppl. Figure 7. Confirmation of the splice junction and presence of cT1799A/V600E mutation in the alternatively spliced BRAF sequence. Suppl. Figure 8. Comparison of gene expression levels in PV1, PV2 and vemurafenib-naive metastasis
Supplementary Table 2 from Identification of a Subset of Human Non–Small Cell Lung Cancer Patients with High PI3Kβ and Low PTEN Expression, More Prevalent in Squamous Cell Carcinoma
Authors: Cumberbatch Marie , Tang Ximing , Beran Garry , Eckersley Sonia , Wang Xin , Ellston Rebecca P.A. , Dearden Simon , Cosulich Sabina , Smith Paul D. , Behrens Carmen , Kim Edward S. , Su Xinying , Fan Shuqiong , Gray Neil , Blowers David P. , Wistuba Ignacio I. , Womack Chris
Published: April 2023

PDF file - 61K, Clinicopathological features of TMA Set 2.
Supplementary Figures 1 - 3 from Co-Clinical Trials Demonstrate Superiority of Crizotinib to Chemotherapy in ALK-Rearranged Non–Small Cell Lung Cancer and Predict Strategies to Overcome Resistance
Authors: Chen Zhao , Akbay Esra , Mikse Oliver , Tupper Tanya , Cheng Katherine , Wang Yuchuan , Tan Xiaohong , Altabef Abigail , Woo Sue-Ann , Chen Liang , Reibel Jacob B. , Janne Pasi A. , Sharpless Norman E. , Engelman Jeffrey A. , Shapiro Geoffrey I. , Kung Andrew L. , Wong Kwok-Kin
Published: April 2023

PDF file - 806K, Supplemental Figure 1. MRI scans at the indicated time points showing tumor burden in EML4-ALK lung cancer mice treated by crizotinib. Multiple scans from a total of 4 mice are shown. Supplemental Figure 2. Representative MRI images showing that EML4-ALK F1174L mutant lung cancers respond to 17-DMAG and TAE684. Note the development of acquired resistance to 17-DMAG and TAE684 after prolonged treatment. Supplemental Figure 3. Acquired resistance to 17-DMAG and TAE684 in mice bearing tumors driven by the EML4-ALK F1174L mutant can be overcome by the combination of the two drugs.
Supplementary Figure 4 from Identification of a Subset of Human Non–Small Cell Lung Cancer Patients with High PI3Kβ and Low PTEN Expression, More Prevalent in Squamous Cell Carcinoma
Authors: Cumberbatch Marie , Tang Ximing , Beran Garry , Eckersley Sonia , Wang Xin , Ellston Rebecca P.A. , Dearden Simon , Cosulich Sabina , Smith Paul D. , Behrens Carmen , Kim Edward S. , Su Xinying , Fan Shuqiong , Gray Neil , Blowers David P. , Wistuba Ignacio I. , Womack Chris
Published: April 2023

PDF file - 129K, Reduced nuclear PTEN in SCC compared with AC (TMA Set 2).
Supplemental from Imaging the Norepinephrine Transporter in Neuroblastoma: A Comparison of [18F]-MFBG and 123I-MIBG
Authors: Zhang Hanwen , Huang Ruimin , Cheung Nai-Kong V. , Guo Hongfen , Zanzonico Pat B. , Thaler Howard T. , Lewis Jason S. , Blasberg Ronald G.
Published: April 2023

MATERIALS AND METHODS Table S1. Biodistribution of [18F]-MFBG in neuroblastoma xenografts. Table S2. Biodistribution of 123I-MIBG in neuroblastoma xenografts.
Supplementary Figure 2 from Identification of a Subset of Human Non–Small Cell Lung Cancer Patients with High PI3Kβ and Low PTEN Expression, More Prevalent in Squamous Cell Carcinoma
Authors: Cumberbatch Marie , Tang Ximing , Beran Garry , Eckersley Sonia , Wang Xin , Ellston Rebecca P.A. , Dearden Simon , Cosulich Sabina , Smith Paul D. , Behrens Carmen , Kim Edward S. , Su Xinying , Fan Shuqiong , Gray Neil , Blowers David P. , Wistuba Ignacio I. , Womack Chris
Published: April 2023

PDF file - 221K, Validation of PTEN antibody across FFPE xenograft samples.
Supplementary Figure Legends from Antagonism of SET Using OP449 Enhances the Efficacy of Tyrosine Kinase Inhibitors and Overcomes Drug Resistance in Myeloid Leukemia
Authors: Agarwal Anupriya , MacKenzie Ryan J. , Pippa Raffaella , Eide Christopher A. , Oddo Jessica , Tyner Jeffrey W. , Sears Rosalie , Vitek Michael P. , Odero María D. , Christensen Dale J. , Druker Brian J.
Published: April 2023

PDF file - 94KB
Supplementary Figure Legend from The mTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-Activated Glioblastomas
Authors: Gini Beatrice , Zanca Ciro , Guo Deliang , Matsutani Tomoo , Masui Kenta , Ikegami Shiro , Yang Huijun , Nathanson David , Villa Genaro R. , Shackelford David , Zhu Shaojun , Tanaka Kazuhiro , Babic Ivan , Akhavan David , Lin Kelly , Assuncao Alvaro , Gu Yuchao , Bonetti Bruno , Mortensen Deborah S. , Xu Shuichan , Raymon Heather K. , Cavenee Webster K. , Furnari Frank B. , James C. David , Kroemer Guido , Heath James R. , Hege Kristen , Chopra Rajesh , Cloughesy Timothy F. , Mischel Paul S.
Published: April 2023

PDF file - 91K
Supplementary Figure 6 from The mTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-Activated Glioblastomas
Authors: Gini Beatrice , Zanca Ciro , Guo Deliang , Matsutani Tomoo , Masui Kenta , Ikegami Shiro , Yang Huijun , Nathanson David , Villa Genaro R. , Shackelford David , Zhu Shaojun , Tanaka Kazuhiro , Babic Ivan , Akhavan David , Lin Kelly , Assuncao Alvaro , Gu Yuchao , Bonetti Bruno , Mortensen Deborah S. , Xu Shuichan , Raymon Heather K. , Cavenee Webster K. , Furnari Frank B. , James C. David , Kroemer Guido , Heath James R. , Hege Kristen , Chopra Rajesh , Cloughesy Timothy F. , Mischel Paul S.
Published: April 2023

PDF file - 2561K, Treatment with CC214-1, leads to induction of autophagy in GBM39 cells and genetic inhibition of autophagy sensitizes U87EGFRvIII cells to apoptosis.
Supplementary Figure 1 from Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of Dalantercept, an Activin Receptor–like Kinase-1 Ligand Trap, in Patients with Advanced Cancer
Authors: Bendell Johanna C. , Gordon Michael S. , Hurwitz Herbert I. , Jones Suzanne F. , Mendelson David S. , Blobe Gerard C. , Agarwal Neeraj , Condon Carolyn H. , Wilson Dawn , Pearsall Amelia E. , Yang Yijun , McClure Ty , Attie Kenneth M. , Sherman Matthew L. , Sharma Sunil
Published: April 2023

PDF file - 7635K, Mean (plus-minus standard error) serum concentration of dalantercept versus time after first dose for each dose level.
Supplementary Figure 2 from Effects of MAPK and PI3K Pathways on PD-L1 Expression in Melanoma
Authors: Atefi Mohammad , Avramis Earl , Lassen Amanda , Wong Deborah J.L. , Robert Lidia , Foulad David , Cerniglia Michael , Titz Bjoern , Chodon Thinle , Graeber Thomas G. , Comin-Anduix Begonya , Ribas Antoni
Published: April 2023

PDF file - 206KB, Restoration of the MAPK pathway activity by vemurafenib in lymphocytes exposed to PD-L1.
Supplementary Figure 1 from Effects of MAPK and PI3K Pathways on PD-L1 Expression in Melanoma
Authors: Atefi Mohammad , Avramis Earl , Lassen Amanda , Wong Deborah J.L. , Robert Lidia , Foulad David , Cerniglia Michael , Titz Bjoern , Chodon Thinle , Graeber Thomas G. , Comin-Anduix Begonya , Ribas Antoni
Published: April 2023

PDF file - 247KB, MAPK pathway is almost inactive in resting PBMCs.
Supplementary Figure 1 from Development and Characterization of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinoma Tumorgrafts
Authors: Kimple Randall J. , Harari Paul M. , Torres Alexandra D. , Yang Robert Z. , Soriano Benjamin J. , Yu Menggang , Armstrong Eric A. , Blitzer Grace C. , Smith Molly A. , Lorenz Laurel D. , Lee Denis , Yang David T. , McCulloch Timothy M. , Hartig Gregory K. , Lambert Paul F.
Published: April 2023

PDF file - 384K, Detection of multiple HPV subtypes by degenerate PCR of genomic DNA (A) or by HPV-16 specific Southern blot (B).
Supplementary Table 1 from Identification of microRNA-135b in Stool as a Potential Noninvasive Biomarker for Colorectal Cancer and Adenoma
Authors: Wu Chung Wah , Ng Siew Chien , Dong Yujuan , Tian Linwei , Ng Simon Siu Man , Leung Wing Wa , Law Wai Tak , Yau Tung On , Chan Francis Ka Leung , Sung Joseph Jao Yiu , Yu Jun
Published: April 2023

XLSX file - 33KB, The characteristics of CRC and advancent adenoma patients in tissue miRNA assay.
Supplementary Figure 1 from Identification of microRNA-135b in Stool as a Potential Noninvasive Biomarker for Colorectal Cancer and Adenoma
Authors: Wu Chung Wah , Ng Siew Chien , Dong Yujuan , Tian Linwei , Ng Simon Siu Man , Leung Wing Wa , Law Wai Tak , Yau Tung On , Chan Francis Ka Leung , Sung Joseph Jao Yiu , Yu Jun
Published: April 2023

PDF file - 141KB, Flow-chart of exclusion of subjects in the study.
Supplementary Tables 1 - 3 from Overexpression of Sirt7 Exhibits Oncogenic Property and Serves as a Prognostic Factor in Colorectal Cancer
Authors: Yu Hongyan , Ye Wen , Wu Jiangxue , Meng Xiangqi , Liu Ran-yi , Ying Xiaofang , Zhou Yi , Wang Hui , Pan Changchuan , Huang Wenlin
Published: April 2023

PDF file - 178KB, Supplementary Table 1. Clinicopathological findings and correlation with Sirt7 expression. Supplementary Table 2. Univariate analysis of clinicopathological parameters and molecular expression ( I and II). Supplementary Table 3. Multivariate analysis for I and II patients� OS.
Supplementary Materials and Methods from Overexpression of Sirt7 Exhibits Oncogenic Property and Serves as a Prognostic Factor in Colorectal Cancer
Authors: Yu Hongyan , Ye Wen , Wu Jiangxue , Meng Xiangqi , Liu Ran-yi , Ying Xiaofang , Zhou Yi , Wang Hui , Pan Changchuan , Huang Wenlin
Published: April 2023

PDF file - 12KB
Supplementary Figure 4 from Overexpression of Sirt7 Exhibits Oncogenic Property and Serves as a Prognostic Factor in Colorectal Cancer
Authors: Yu Hongyan , Ye Wen , Wu Jiangxue , Meng Xiangqi , Liu Ran-yi , Ying Xiaofang , Zhou Yi , Wang Hui , Pan Changchuan , Huang Wenlin
Published: April 2023

PDF file - 1464KB, Sirt7 mediates ERK1/2 activation and subsequent mitogenic effects.(A) real-time PCR analysis of Sirt7 in THC8307 cells after ectopic expression of different siRNA. (B) Sirt7 induced increase in growth was subsequently rescued with Sirt7 shRNA, mean� SEM, n=3, p<0.001.). (C) Expression of the Sirt7 mutants fails to induce ERK1/2 in 293T cell.
Supplementary Figure 2 from Overexpression of Sirt7 Exhibits Oncogenic Property and Serves as a Prognostic Factor in Colorectal Cancer
Authors: Yu Hongyan , Ye Wen , Wu Jiangxue , Meng Xiangqi , Liu Ran-yi , Ying Xiaofang , Zhou Yi , Wang Hui , Pan Changchuan , Huang Wenlin
Published: April 2023

PDF file - 1787KB, Ectopic overexpression of Sirt7 enhances colorectal carcinoma cells migration in vitro. Representative results of transwell assays demonstrate that down-regulation Sirt7 expression levels in SW620 inhibited the cells migration compared the NC group. Columns - mean of triplicate experiments. *, p<0.05, independent student's test.
Supplementary Figure 4 from Reducing TNF Receptor 2+ Regulatory T Cells via the Combined Action of Azacitidine and the HDAC Inhibitor, Panobinostat for Clinical Benefit in Acute Myeloid Leukemia Patients
Authors: Govindaraj Chindu , Tan Peter , Walker Patricia , Wei Andrew , Spencer Andrew , Plebanski Magdalena
Published: April 2023

PDF file - 1561K, The expression levels of CD25 on TNFR2-FOXP3- and TNFR2+FOXP3+ T cells within healthy and AML patients.
Supplementary Table 2 from Trial Designs for Personalizing Cancer Care: A Systematic Review and Classification
Authors: Tajik Parvin , Zwinderman Aleiko H. , Mol Ben W. , Bossuyt Patrick M.
Published: April 2023

PDF file - 139K, Extracted labels.
Supplementary Table and Figures from Characterization of CD45−/CD31+/CD105+ Circulating Cells in the Peripheral Blood of Patients with Gynecologic Malignancies
Authors: Yu Hyun-Kyung , Lee Ho-Jeong , Choi Ha-Na , Ahn Jin-Hyung , Choi Ji-Young , Song Haeng-Seok , Lee Ki-Heon , Yoon Yeup , Yi Lee S. H. , Kim Jang-Seong , Kim Sun Jin , Kim Tae Jin
Published: April 2023

Supplementary Table and Figures - PDF file 237K, Supplementary Table 1. Clinical characteristics of cancer patients. Supplementary Fig. 1. Isolation of CD45+/CD31- cells, CD45+/CD31bright cells, and CD45-/CD31+ cells from PBMCs using FACSAria flow cytometer. Supplementary Fig. 2. A Venn diagram showing the expression of various antigens in the endothelial cells, platelets, and monocytes
Supplementary Tables 4 through 6 from Busulfan in Infant to Adult Hematopoietic Cell Transplant Recipients: A Population Pharmacokinetic Model for Initial and Bayesian Dose Personalization
Authors: McCune Jeannine S. , Bemer Meagan J. , Barrett Jeffrey S. , Scott Baker K. , Gamis Alan S. , Holford Nicholas H.G.
Published: April 2023

PDF file 45K, Empirical estimates of allometric exponents; correlation of between subject and between occasion variabilities of pharmacokinetic parameters; and evaluation of alternative models created from pediatric datasets
Supplementary Table 1 from Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of αvβ6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence
Authors: Allen Michael D. , Thomas Gareth J. , Clark Sarah , Dawoud Marwa M. , Vallath Sabarinath , Payne Sarah J. , Gomm Jennifer J. , Dreger Sally A. , Dickinson Sarah , Edwards Dylan R. , Pennington Caroline J. , Sestak Ivana , Cuzick Jack , Marshall John F. , Hart Ian R. , Jones J. Louise
Published: April 2023

PDF file - 55K, Supplementary Table 1. Details relating to; treatment received, patient age, hormone replacement therapy, mean follow up and pathological characteristics for cases and controls.
Supplementary Figure 1 from Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of αvβ6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence
Authors: Allen Michael D. , Thomas Gareth J. , Clark Sarah , Dawoud Marwa M. , Vallath Sabarinath , Payne Sarah J. , Gomm Jennifer J. , Dreger Sally A. , Dickinson Sarah , Edwards Dylan R. , Pennington Caroline J. , Sestak Ivana , Cuzick Jack , Marshall John F. , Hart Ian R. , Jones J. Louise
Published: April 2023

PDF file - 106K, Supplementary Figure 1. Transient transfection of alphavbeta6 in primary myoepithelial cells.
Supplementary Figure 3 from Cabozantinib Inhibits Prostate Cancer Growth and Prevents Tumor-Induced Bone Lesions
Authors: Dai Jinlu , Zhang Honglai , Karatsinides Andreas , Keller Jill M. , Kozloff Kenneth M. , Aftab Dana T. , Schimmoller Frauke , Keller Evan T.
Published: April 2023

PDF file 56K, Cabozantinib increases osteoblast perimeter and decreases osteoclast perimeter in non-tumor bone
Supplementary Figure 3 from Antitumoral Activity of Lenalidomide in In Vitro and In Vivo Models of Mantle Cell Lymphoma Involves the Destabilization of Cyclin D1/p27KIP1 Complexes
Authors: Moros Alexandra , Bustany Sophie , Cahu Julie , Saborit-Villarroya Ifigènia , Martínez Antonio , Colomer Dolors , Sola Brigitte , Roué Gaël
Published: April 2023

PDF file - 3780K, (A) Accumulation of p27KIP1 and activated capase-3 in cytosol-enriched protein extracts from Rec-1 cells cultured for 72 h with 1 μmol/L lenalidomide and subjected to a Human apoptosis antibody array (R&D Systems).
Supplementary Table 2 from Cumulative Genetic Risk Predicts Platinum/Taxane-Induced Neurotoxicity
Authors: McWhinney-Glass Sarah , Winham Stacey J. , Hertz Daniel L. , Yen Revollo Jane , Paul Jim , He Yijing , Brown Robert , Motsinger-Reif Alison A. , McLeod Howard L.
Published: April 2023

PDF file, 69K, 1536 candidate SNPs, chosen based on LD, putative function, and prior literature evidence.
Supplementary Table 1 from Cumulative Genetic Risk Predicts Platinum/Taxane-Induced Neurotoxicity
Authors: McWhinney-Glass Sarah , Winham Stacey J. , Hertz Daniel L. , Yen Revollo Jane , Paul Jim , He Yijing , Brown Robert , Motsinger-Reif Alison A. , McLeod Howard L.
Published: April 2023

PDF file, 54K, 60 candidate genes (nerve-related genes, inherited peripheral neuropathy genes, and drug-related genes).
Supplementary Figure 3 from DNA Methyltransferase Inhibition Reverses Epigenetically Embedded Phenotypes in Lung Cancer Preferentially Affecting Polycomb Target Genes
Authors: Hascher Antje , Haase Ann-Kristin , Hebestreit Katja , Rohde Christian , Klein Hans-Ulrich , Rius Maria , Jungen Dominik , Witten Anika , Stoll Monika , Schulze Isabell , Ogawa Seishi , Wiewrodt Rainer , Tickenbrock Lara , Berdel Wolfgang E. , Dugas Martin , Thoennissen Nils H. , Müller-Tidow Carsten
Published: April 2023

PDF file - 247K, Supplementary Figure 3 Unsupervised hierarchical clustering shows that independent samples at each step of selection cluster more closely together than individual cell lines A549 (A) and HTB56 (B). A high correlation between biological replicates from normal and highly aggressive cell lines from both cell types were observed. The clustering is based on a distance matrix, which has been derived from pearson product-moment correlation coefficients (r) by calculating 1-r.
Supplementary Table 5 from Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer
Authors: Torres Sofia , Bartolomé Rubén A. , Mendes Marta , Barderas Rodrigo , Fernandez-Aceñero M. Jesús , Peláez-García Alberto , Peña Cristina , Lopez-Lucendo María , Villar-Vázquez Roi , de Herreros Antonio García , Bonilla Felix , Casal J. Ignacio
Published: April 2023

PDF file - 184K, List of proteins differentially-expressed in the conditioned medium of CAFs with a fold-change >1.4
Supplementary Table 1 from Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer
Authors: Torres Sofia , Bartolomé Rubén A. , Mendes Marta , Barderas Rodrigo , Fernandez-Aceñero M. Jesús , Peláez-García Alberto , Peña Cristina , Lopez-Lucendo María , Villar-Vázquez Roi , de Herreros Antonio García , Bonilla Felix , Casal J. Ignacio
Published: April 2023

XLSX file - 64K, List of antibodies used in the different applications
Supplementary Legend from A Phase I Study of Quisinostat (JNJ-26481585), an Oral Hydroxamate Histone Deacetylase Inhibitor with Evidence of Target Modulation and Antitumor Activity, in Patients with Advanced Solid Tumors
Authors: Venugopal Balaji , Baird Richard , Kristeleit Rebecca S. , Plummer Ruth , Cowan Richard , Stewart Adam , Fourneau Nele , Hellemans Peter , Elsayed Yusri , Mcclue Steve , Smit Johan W. , Forslund Ann , Phelps Charles , Camm John , Evans T.R. Jeffry , de Bono Johann S. , Banerji Udai
Published: April 2023

Supplementary Legend - PDF file 66K, Supplementary legend
Supplementary Tables from MicroRNA-31 Predicts the Presence of Lymph Node Metastases and Survival in Patients with Lung Adenocarcinoma
Authors: Meng Wei , Ye Zhenqing , Cui Ri , Perry James , Dedousi-Huebner Vaia , Huebner Alexander , Wang Yao , Li Bin , Volinia Stefano , Nakanishi Hiroshi , Kim Taewan , Suh Sung-Suk , Ayers Leona W. , Ross Patrick , Croce Carlo M. , Chakravarti Arnab , Jin Victor X. , Lautenschlaeger Tim
Published: April 2023

PDF file, 34K, Supplementary Table 1. Clinical demographic information of 43 lung ADC cases. NAT is normal adjacent tissue. Supplementary Table 2. Clinical demographic information of lung adenocarcinoma TCGA patients. Supplementary Table 3. IPA analysis for the downstream targets for miR-31. Supplementary Table 4. Genetic alteration overview of the cell lines used in this study. Supplementary Table 5. Correlation coefficient between EMT-related genes and miR-31 expression.
Supplementary Figure 3 from Combination Immunotherapy after ASCT for Multiple Myeloma Using MAGE-A3/Poly-ICLC Immunizations Followed by Adoptive Transfer of Vaccine-Primed and Costimulated Autologous T Cells
Authors: Rapoport Aaron P. , Aqui Nicole A. , Stadtmauer Edward A. , Vogl Dan T. , Xu Yin Yan , Kalos Michael , Cai Ling , Fang Hong-Bin , Weiss Brendan M. , Badros Ashraf , Yanovich Saul , Akpek Gorgun , Tsao Patricia , Cross Alan , Mann Dean , Philip Sunita , Kerr Naseem , Brennan Andrea , Zheng Zhaohui , Ruehle Kathleen , Milliron Todd , Strome Scott E. , Salazar Andres M. , Levine Bruce L. , June Carl H.
Published: April 2023

PDF file - 40KB, ELISA Antibody Responses for the PCV (Prevnar-13(registered trademark)).
Supplementary Figure 3 from Glioma Grade Is Associated with the Accumulation and Activity of Cells Bearing M2 Monocyte Markers
Authors: Prosniak Michael , Harshyne Larry A. , Andrews David W. , Kenyon Lawrence C. , Bedelbaeva Kamila , Apanasovich Tatiyana V. , Heber-Katz Ellen , Curtis Mark T. , Cotzia Paolo , Hooper D. Craig
Published: April 2023

PDF - 52K, Analysis of the changes in expression of IL-10 and M2 markers during culture of single cells isolated from GBM.
Supplementary Figure 1 from First-in-human, Pharmacokinetic and Pharmacodynamic Phase I Study of Resminostat, an Oral Histone Deacetylase Inhibitor, in Patients with Advanced Solid Tumors
Authors: Brunetto André T. , Ang Joo Ern , Lal Rohit , Olmos David , Molife L. Rhoda , Kristeleit Rebecca , Parker Ann , Casamayor Isabel , Olaleye Muyibat , Mais Anna , Hauns Bernhard , Strobel Vera , Hentsch Bernd , de Bono Johann S.
Published: April 2023

Supplementary figure 1. Plot of resminostat concentration versus degree of HDAC enzyme inhibition at 2 hour post-dose on day 1 for all dose levels using the Hill model.
Supplementary Figure 1 from Increased KIT Inhibition Enhances Therapeutic Efficacy in Gastrointestinal Stromal Tumor
Authors: Kim Teresa S. , Cavnar Michael J. , Cohen Noah A. , Sorenson Eric C. , Greer Jonathan B. , Seifert Adrian M. , Crawley Megan H. , Green Benjamin L. , Popow Rachel , Pillarsetty Nagavarakishore , Veach Darren R. , Ku Anson T. , Rossi Ferdinand , Besmer Peter , Antonescu Cristina R. , Zeng Shan , DeMatteo Ronald P.
Published: April 2023

PDF file - 119KB, Supplemental Figure S1. Additional PLX3397-mediated immune effects.
Supplementary Table S3 from Expression Defect Size among Unclassified MLH1 Variants Determines Pathogenicity in Lynch Syndrome Diagnosis
Authors: Hinrichsen Inga , Brieger Angela , Trojan Jörg , Zeuzem Stefan , Nilbert Mef , Plotz Guido
Published: April 2023

PDF file - 100 KB, Statistical analysis of expression
Supplementary Tabe S1 from Expression Defect Size among Unclassified MLH1 Variants Determines Pathogenicity in Lynch Syndrome Diagnosis
Authors: Hinrichsen Inga , Brieger Angela , Trojan Jörg , Zeuzem Stefan , Nilbert Mef , Plotz Guido
Published: April 2023

PDF file - 167 KB, This table contains the source information underlying Table 1 and Figure 2 of the main manuscript.
Supplementary Figures 1-5 from Integrative Genomics Analysis Identifies Candidate Drivers at 3q26-29 Amplicon in Squamous Cell Carcinoma of the Lung
Authors: Wang Jing , Qian Jun , Hoeksema Megan D. , Zou Yong , Espinosa Allan V. , Rahman S.M. Jamshedur , Zhang Bing , Massion Pierre P.
Published: April 2023

Supplementary Figures 1-5 - PDF file 342K, Figure S1. The IGV plot of copy number variation for 152 TCGA samples in 3q regions. The samples are in descending order according to the average expression scores. Figure S2. The effect of knockdown SENP2 expression on NSCLC cells. Figure S3. Three-gene expression-based 3q26-29 stratification informs response to adjuvant chemotherapy on different stage patients. Figure S4 Relationship between patient stratification based on expression value of each of three genes and response to adjuvant chemotherapy. Figure S5. Copy number alteration of SENP family members in TCGA lung SCC dataset (n=177)
Supplementary Methods, Table 1 from A Phase I/II, Multiple-Dose, Dose-Escalation Study of Siltuximab, an Anti-Interleukin-6 Monoclonal Antibody, in Patients with Advanced Solid Tumors
Authors: Angevin Eric , Tabernero Josep , Elez Elena , Cohen Steven J. , Bahleda Rastilav , van Laethem Jean-Luc , Ottensmeier Christian , Lopez-Martin Jose A. , Clive Sally , Joly Florence , Ray-Coquard Isabelle , Dirix Luc , Machiels Jean-Pascal , Steven Neil , Reddy Manjula , Hall Brett , Puchalski Thomas A. , Bandekar Rajesh , van de Velde Helgi , Tromp Brenda , Vermeulen Jessica , Kurzrock Razelle
Published: April 2023

PDF file - 99KB, Supplementary Methods: The supplemental material contains additional detail on the pharmacokinetic and pharmacodynamic methods used during the study as well as a summary table of safety events and a figure detailing patient disposition. Supplemental Table 1: Summary of safety events in all study cohorts.
Supplementary Table 1 from Therapeutic Potential of HSP90 Inhibition for Neurofibromatosis Type 2
Authors: Tanaka Karo , Eskin Ascia , Chareyre Fabrice , Jessen Walter J. , Manent Jan , Niwa-Kawakita Michiko , Chen Ruihong , White Cory H. , Vitte Jeremie , Jaffer Zahara M. , Nelson Stanley F. , Rubenstein Allan E. , Giovannini Marco
Published: April 2023

Supplementary Table 1 - XLS file 28K, PCR primers for NF2 mutation screening