bluuebunny/crossref_metadata_2025 huggingface dataset:
Utilization of Palm Fiber and Sikacim Concrete Additive as Additional Materials in Concrete Mixtures Viewed From the Strength of Pulling
Authors: Zulkarnain Fahrizal , Lubis Delva Enzelya Adila
Published: June 2024

Concrete is an important material used in regional construction. The purpose of this study was to utilize palm fiber as an additive to increase the split tensile strength of concrete. In addition, the sicacim concrete additive is used as a chemical additive in concrete mixtures to produce higher-quality concrete. This study used sicacim concrete additives (0.08% cement) and palm fiber (4%, 5%, and 6% by weight) as cement substitutes. The components of the test object used in this study were vessels with a size of 15 x 30 cm, aged 28 years, and rut values of 60-180 cm—alloy configuration using SNI 03-2834-2000 technique. There are a total of 12 specimens, three for each variation. The finished test is a substantial elasticity test. Based on the research results, the split tensile strength of standard concrete is 3.52 MPa; the split tensile strength of concrete with a mixture of 4% palm fiber and 0.8% sicacim concrete additive is 3.69 MPa; the splitting tensile strength of concrete using a mixture of 5% palm fiber and 0.8% sicacim concrete additive is 4.09 MPa; then the tensile strength of the concrete uses a mixture of 6% palm fiber and 0.8%.ABSTRAKBeton merupakan bahan penting yang digunakan dalam pembangunan daerah. Tujuan penelitian ini adalah memanfaatkan ijuk sebagai bahan tambahan untuk imeningkatkan ikuat itarik ibelah ibeton. iSelain iitu, aditif betonisicacim digunakanisebagaiibahanikimia itambahan idalam campuran betonidalam upaya menghasilkan ibeton iyang ilebih iberkualitas. Dalam penelitian iini, iaditif ibeton isicacim i(0,08% isemen) idan iijuk (4%, 5%, dan 6% berat) digunakan sebagai pengganti semen. Komponen benda uji yang dimanfaatkan pada penelitian ini adalah bejana dengan ukuran yaitu 15 x 30 cm dengan umur 28 tahun, dan nilai rut 60-180 cm. Konfigurasi paduan menggunakan teknik SNI 03-2834-2000. Total ada 12 spesimen, tiga untuk setiap variasi. Uji selesai adalah uji elastisitas substansial. Berdasarkan hasil penelitian, daya tarik belah pada beton normal adalah diangka 3,52 MPa kuat tarik belah beton dengan campuran 4% ijuk dan 0,8% aditif beton sicacim adalah 3,69 MPa; daya tarik belah beton menggunakan bahan campuran 5% ijuk dan 0,8% aditif beton sicacim adalah 4,09 MPa; kemudian daya tarik belah beton menggunakan campuran sebesar 6% ijuk dan 0,8%.
Safety Evaluation of Rockfill Dam Based on Seepage Discharge Data
Authors: Sulistya Krisna , Sachro Sri Sangkawati , Sukamta Sukamta
Published: June 2024

The leading cause of failure of an embankment dam is the occurrence of excessive seepage, which triggers piping that can disrupt the stability and safety of the dam. This study discusses the dam's safety against the danger of seepage with a case study of the Jatibarang Dam. The safety evaluation uses V-notch monitoring data during the operational period from 2018 to 2021. The highest seepage discharge recorded during that period was 2,232 lt/sec/m, where the unsafe threshold for seepage based on the dam's height was 0,56 lt/sec/m, so seepage is unsafe. Meanwhile, based on the seepage discharge index (QI) calculation, the QI value is less than one, so the seepage discharge is still safe. Evaluating dam safety against excessive seepage discharge for dams of the same type as the Jatibarang Dam is more appropriate to use the seepage discharge index (QI) threshold because the parameters in the equation are complete.ABSTRAKPenyebab utama kegagalan suatu bendungan tipe urugan adalah terjadinya rembesan berlebih yang memicu piping yang dapat mengganggu kestabilan dan keamanan bendungan. Penelitian ini membahas keamanan bendungan terhadap bahaya rembesan dengan studi kasus Bendungan Jatibarang.  Evaluasi keamanan menggunakan data pemantauan V-notch selama masa operasional tahun 2018 sampai dengan 2021. Debit rembesan tertinggi yang tercatat pada kurun waktu tersebut sebesar 2,232 lt/dt/m, dimana ambang batas tidak aman terhadap rembesan berdasarkan ketinggian bendungan adalah 0,56 lt/dt/m sehingga rembesan dalam kondisi tidak aman. Sedangkan berdasarkan perhitungan indeks debit rembesan (QI) menghasilkan nilai QI kurang dari satu sehingga debit rembesan masih dalam kondisi aman. Evaluasi keamanan bendungan terhadap debit rembesan berlebih terhadap bendungan yang se-tipe Bendungan Jatibarang lebih tepat menggunakan ambang batas indeks debit rembesan (QI) karena parameter pada persamaannya lebih lengkap.
Congestion Charge Analysis for Private Vehicle Users in the Central Business District (Case Study: Jalan Pemuda-Pandanaran-Ahmad Yani, Semarang City)
Authors: Utami Adita , Qumara Nadhiyah Ayu , Nurhidayat Asep Yayat
Published: June 2024

Semarang, part of the Kedungsepur area, has a population of 1,656,564 with an average annual growth of 1.57%. The increase in population can increase the intensity of trips, so good transportation infrastructure is needed. The presence of the Central Business District (CBD) area in Semarang, precisely on Jalan Pemuda-Pandanaran-Ahmad Yani, often results in congestion. The purpose of this research was to provide recommendations for solutions in the form of a study on applying congestion charges to private vehicles to overcome congestion on the road. This research uses traffic analysis to determine the performance of existing roads using the PKJI 2014 method. After knowing the traffic performance, modeling the mode selection of private cars for BRT Trans Semarang was carried out using the logit binomial difference method. In this study, three travel attributes were considered influential in the choice of mode: travel time, congestion costs, and frequency. The private car utility equation for BRT Trans Semarang is obtained with a value of U=-11.3774-0.2639(X1)-0.0120(X2)-1.5403(X3). Based on the research results, a congestion charge of IDR 10,000 was obtained, with the percentage of private car users switching to BRT Trans Semarang at 79.8%. So implementing a congestion charge is considered adequate to reduce the congestion on the road.ABSTRAKKota Semarang merupakan bagian dari kawasan Kedungsepur memiliki 1.656.564 jiwa penduduk dengan pertumbuhan rata-rata tiap tahun sebesar 1,57%. Peningkatan jumlah penduduk tersebut berpotensi meningkatkan intensitas perjalanan, sehingga dibutuhkan sarana prasarana transportasi yang baik. Adanya Central Business District (CBD) kawasan di kota Semarang tepatnya di Jalan Pemuda-Pandanaran-Ahmad Yani sering mengakibatkan kemacetan. Sehingga tujuan penelitian ini dilakukan untuk memberikan rekomendasi solusi berupa kajian penerapan congestion charge terhadap kendaraan mobil pribadi, untuk mengatasi kemacetan lalu lintas di Jalan tersebut. Diawali dengan melakukan analisis lalu lintas untuk mengetahui kinerja ruas jalan eksisting dengan metode PKJI 2014. Selanjutnya setelah diketahui kinerja lalu lintasnya, dilakukan pemodelan pemilihan moda mobil pribadi terhadap BRT Trans Semarang dengan metode logit binomial selisih.  Penelitian ini menggunakan 3 atribut perjalanan yang dinilai berpengaruh dalam pemilihan moda yaitu waktu tempuh, biaya kemacetan, dan frekuensi. Didapatkan persamaan utilitas mobil pribadi terhadap BRT Trans Semarang dengan nilai U = - 11.3774 - 0.2639 (X1) - 0.0120 (X2) - 1.5403 (X3). Nilai congestion charge diperoleh Rp.10.000 dengan persentase pengguna mobil pribadi yang akan berpindah menggunakan BRT Trans Semarang sebesar 79,8%. Sehingga adanya skenario penerapan congestion charge dinilai cukup efektif untuk menurunkan tingkat kemacetan dijalan tersebut.
Experimental Study on the Failure of Bamboo Laminated Hollow Section Beam-Column Joints using Glue-in-Rod Bracket
Authors: Arifin Achmad Saiful , Karyadi Karyadi , Nindyawati Nindyawati
Published: June 2024

Building materials that emit pollutants, are non-renewable, and generate environmental waste require attention. Wood, a popular and natural material, is facing increasing scarcity, necessitating a substitute. Laminated bamboo emerges as the most akin and natural alternative to wood. Research into laminated bamboo encompasses diverse cross-sections, joint types, and field applications, demanding further investigation.This study aimed to ascertain failure types and damage patterns in laminated bamboo hollow section beam-column joints modified with glue-in rod-bracket connections, using petung bamboo (dendrocalamus asper). The research employed an experimental approach with descriptive analysis. Joint failures were evaluated based on moment-rotation relationships within prescribed rotational limits per standards, while joint damage was assessed through visual inspection of joint components.The study's dependent variables included thread rod diameters of 6 mm, 8 mm, 10 mm, and 4 6 embedded thread rods, while the independent variables were failure types and joint collapses. Results revealed serviceability failures in samples 8.6, 10.4, and 10.6. Joint damage across all test specimens primarily manifested as broken thread rods. The highest joint strength observed was 6.28 kNm in sample 10.6, with the lowest at 2.25 kNm in sample 6.4.Based on the findings, increasing thread rod diameters to achieve ductile joints resulted in longer rotations but did not meet the planned strength due to bracket-induced prying effects causing bolt head failure. Despite this, the collapse type aligned with the research plan. Addressing the bracket's fulcrum effect during field applications requires solutions, potentially involving enlarging the bracket's base and increasing the number of thread rod points. The tests did not damage the laminated bamboo components, emphasizing the need to consider laminated bamboo cross-sectional dimensions and thread rod fulcrum effects in subsequent tests to ensure uniform component performance.
Paper Waste Hydrolysis with Stepwise Sulfuric Acid Catalyst
Authors: Panjaitan Jabosar Ronggur Hamonangan , Nury Dennis Farina , Hutabarat Fransisco Xala , Hutabarat Monalisa
Published: June 2024

The need for paper results in a lot of paper waste. Paper waste, which is lignocellulosic, can be hydrolyzed using an acid catalyst to produce various cellulose degradation products. In this study, the effect of the sulfuric acid catalyst addition method on the waste paper hydrolysis process was investigated. The addition of the catalyst was carried out in three types. The Type-1 method was sulfuric acid addition in the 0th minute. The Type-2 method was sulfuric acid addition in the 0th and 30th minutes. The Type-3 method was sulfuric acid addition every 10 minutes. The results showed that the lowest residual mass of waste paper hydrolyzed was produced using the Type-3 method. This showed that the Type-3 method, sulfuric acid addition every 10 minutes, had an effect on the residual mass of the hydrolyzed sample. The Type-3 method was the most effective type of sulfuric acid catalyst addition compared to other types. On the other hand, variations in the concentration of the sulfuric acid catalyst affect the residual mass of the waste paper hydrolyzed sample, where higher sulfuric acid concentration will lower residual mass. The catalyst concentration of 2% sulfuric acid with The Type-3 addition method resulted in the highest conversion which was 38.27%.
The Effect of Catalyst Amount and Time on the Results of Converting Rubber Wood Chip Waste by Catalytic Pyrolysis into Alternative Energy
Authors: Patrio Aditia , Rusnadi Irawan , Syarif Aida
Published: June 2024

In the rubber plantations of South Sumatra, covering an area of 1,013,969 hectares, there exists an underutilized waste stream known as rubber wood waste. This waste can be subjected to pyrolysis to Yield char, bio-oil, and syngas products. This research is centred on pyrolyzing rubber wood waste, employing various zeolite catalysts and time durations, to explore the potential of alternative energy sources and calculate the Specific Energy Consumption (SEC). The pyrolysis results, with variations in catalysts and time, indicate that the optimal combination is at a temperature of 390°C, using 6% zeolite catalyst, and a duration of 70 minutes. The resultant Yields comprise char at 21.73% with a calorific value of 6264.87 kcal/g, bio-oil at 22.50%, and syngas at 45.28% with a CH4 content of 55.52%. The most SEC-optimal variation is at a temperature of 390°C, using a 6% zeolite catalyst, and 30 minutes, with an SEC value of 3.25 kWh/L.
Sikahyflex-Epoxy Mixed Adhesive’s Effect on the Aluminum-Composite Joint’s Shear Tensile Strength for the Automotive Industry
Authors: Hastuti Sri , Paryanto Paryanto , Sugiyanto Gito , Salahudin Xander , Afandi Ridwan , Azhari Fadlan
Published: June 2024

The automotive industry sector encounters challenges in the construction of connections between different materials. Hence, a breakthrough is needed in the automotive industry in manufacturing connections between different wall panel materials. Mixed adhesive materials for different materials are required and represent an innovation in the manufacturing process for joints of different materials due to the need for stiff and slightly ductile adhesives. This research aims to analyze the effect of using a sikahyflex-epoxy mixture adhesive in aluminum-composite joints on the shear tensile strength of the joints for the automotive industry. This research serves as an innovation in dissimilar material connection systems by developing the use of mixed adhesives and cocofiber aluminum-composite adherend materials with environmentally friendly and corrosion-resistant properties. The research material used aluminum 5083-cocofiber composite. The adherend surface was roughened employing sandpaper of #60, #80, and #150. The adhesive used the addition of sikahyflex adhesive to the epoxy adhesive with additional variations of 10%, 20%, 30%, and 40% sikahyflex. Connections between different materials with the single lap joint type refer to ASTM D1002. The roughness test results yielded the best roughness grade #150 on the surface of the aluminum adherend and coco fiber composite. The shear tensile test results by adding 40% sikahyflex adhesive, 0.4 mm adhesive thickness, and #150 sandpapering resulted in a 20% increase in shear tensile strength in the single lap joint of 2.51 N/mm2. The surface roughness enhanced the adhesive bond strength between mechanical interlocking adhesives and adherend. Meanwhile, the failure modes observed in macro observations included thin-layer cohesive failure, cohesive failure, two-stage failure, and stock-break failure modes. The SEM observation revealed that in the initial propagation of microcracking and voids, which mark the initial onset of adhesive failure, tearing took place, leading to a failure mode in the aluminum-composite coco fiber single overlap joint.
Shear Capacity on Corroded Fly Ash Reinforced Concrete Beam Using Galvanostatic Method
Authors: Mooy Merzy , Manubulu Christiani Chandra , Bees Azarya , Bela Krisantos Ria
Published: June 2024

Corrosion can be triggered by a chemical reaction to the materials, establishing reinforced concrete's failure. For a long time, researchers have tried to find out how to prevent corrosion, a main structural construction issue. As a technology of waste material, fly ash has predominance, i.e., it is safer and greener than Portland cement. The finer size of fly ash can be an advantage in filling the concrete materials well. This research is about using fly ash as supplementary material on reinforced concrete beams and the galvanostatic method to accelerate corrosion. This research will compare the shear strength after corrosion of each normal beam and fly ash as a supplementary beam. A shear test of fly ash and a normal reinforced beam has been applied. Results showed that fly ash beams have 14% higher compressive strength and 3% higher shear strength with 14% smaller crack width than normal beams after corrosion. It also has a 3,5 times lower rate and 62% level of corrosion than normal beam
Climate Change Impact on Water Availability and Water Balance on Sampit Sub-Cachtment, Central Kalimantan
Authors: Sulistyani Kiki Frida , Irianto Danang Bimo
Published: June 2024

Sampit River is part of the Mentaya catchment area, located in the East Kotawaringin Regency, Central Kalimantan, Indonesia. Sampit River is generally used as a water supply for domestic, industrial, and livestock needs. The Mentaya River water balance shows that for the year 2030 projection, the Sampit River is expected to experience a deficit, specifically during the first period of the month of October. This research was conducted using the SSP 1 2.6 climate change scenario. In this scenario, it is estimated that rainfall will change from +2.282 to +1.020% and increase in temperature ranging from 0.441-0.793 oC within the period 2021-2030 to 2041-2050. The calculation of 90% dependable flow shows climate change impacts the period of the year 2030 to 2050 when compared to the existing dependable flow. Likewise, the 95% dependable flow for river maintenance, also increases. The research concludes that the water balance endures climate change impact and the calculated deficit remains the same for the first period of the month of October. The results of the water balance show that until 2050 climate change had not impeded negative effects but cautionary efforts must be taken as there an increasing deficits for the years 2040 and 2050.
Pendampingan Pengenalan dan Pembuatan Alat-Alat Peraga IPA Pada Program Studi Pendidikan IPA
Authors: Samputri Salma , Ramlawati Ramlawati , Arif Rifda Nur Hikmahwati , Muhiddin Nurhayani H , Muhiddin St. Mulia Alfiyanti
Published: June 2024

Science teaching aids (props, experimental equipment) are tools used to teach students something so that they can learn something in their subject. Based on the community service results obtained, it can be concluded that the response from alumni of the Science Education Study Program, Faculty of Mathematics, Makassar State University regarding 1) Understanding teaching aids, namely 88.2%, strongly agreed, and the other 11.8% answered agree.  2) 76.5% of the tools used to make the props strongly agreed and the other 23.5% answered agree. 3) Responses regarding various types of props were 76.5% strongly agree, and the other 23.5% answered agree.
Pendampingan BUMDes dan Usaha Mikro Melalui Program Membangun Kemitraan Untuk Akses Modal
Authors: Teguh Muhammad , Harunnurrasyid Harunnurrasyid , Kartasari Shelly Febriana , Melliny Vinny Dwi , Gustriani Gustriani , Novi Yarsah Waldi
Published: June 2024

Villages, as the smallest sphere of society in the country, are often forgotten as an effort to realize it. To improve the village economy, BUMDes should be a body that has an important role. However, this is not reflected because Kembahang II Village itself only has one operating BUMDes, namely BUMDes Sumber Maju. Therefore, counseling and training related to BUMDes is needed for the village community. The community service team of the Faculty of Economics, Sriwijaya University, has conducted training on micro-enterprises through a program to build partnerships for access to capital and business financing in Ulak Kembahang II Village. The results obtained from the service training are the provision of educational material on how to manage micro businesses through the development of village business proposal profiles through the development of BUMDes so that later it can encourage the economic growth of Ulak Kembahang II Village to run well. The level of understanding of the participants who attended the training was evidenced by the level of thinking about the objectives and benefits of the training material that had been provided by 64.0% answering strongly agree and 36.0% only answering agree from the total number of participants present of 25 participants.
One Chaperone to Rule Them All: Deciphering How Chromatin is Assembled During DNA Replication
Authors:   , Rouillon Clément André Philippe
Published: June 2024

Genomic DNA, which governs cellular life, resides within the nucleus of every human cell. Inside each nucleus lies approximately two meters of DNA, posing a significant challenge, akin to compacting 20 kilometers of thread into a tennis ball. To overcome this challenge, DNA is packaged by wrapping itself around proteins called histones, forming individual structures known as nucleosomes. This succession of nucleosomes creates an organization that resembles beads on string, commonly referred to as chromatin.

Histones not only serve as a structural framework for the chromatin; they also regulate its accessibility by carrying chemical modifications that directly impact vital cellular processes. Preserving this chromatin information, also referred to as epigenetic information, is crucial to ensuring the survival of each cell and, by extension, the organism.
Throughout life, many cell types in the human body undergo cell divisions (like skin cells for instance). However, before any cell division can occur, the cell must replicate its genetic content to provide an intact copy of the genome to the future two daughter cells. This process is known as DNA replication. Alongside DNA replication, epigenetic information on histones is meticulously reconstituted, via a process called chromatin replication. Failure in chromatin replication would severely affect the function and identity of the future daughter cells. For instance, a skin cell that failed to replicate its chromatin before dividing, would give rise to two daughter cells that are no longer skin cells.
Chromatin replication involves the wrapping of DNA around histones to form chromatin. To ensure the smooth progress of this operation, histone proteins, known for their instability and propensity for aggregation, require careful handling. Histone chaperones, a class of proteins, take charge of protecting histones, ensuring their controlled trafficking, and facilitating their deposition onto the DNA. In the context of chromatin replication, the histone chaperone Chromatin Assembly Factor 1 (CAF-1) plays a central role by directly depositing histones onto the DNA. CAF-1 is precisely targeted to DNA synthesis sites through direct interaction with the protein PCNA. The work presented in this thesis explores the complex coordination between CAF-1 and PCNA in chromatin replication by examining the dynamics of their interaction during DNA synthesis.
Hand Washing Practices and Antibiotic Susceptibility of Palmar Bacterial Flora in a Tertiary Education Institution in Nigeria
Authors: Akinwumi Florence , Ifeyinwa Okorafor Chiamaka , Ukatu Lawrencia , Akinkunmi Ezekiel
Published: June 2024

Introduction: Hand hygiene is one of the most effective and inexpensive means of preventing the spread of communicable diseases. Rates of handwashing worldwide are low, and poor handwashing practices in universities remain a public health challenge.

Objective: The objective of this study was to examine the practice of handwashing, the microbial communities, and the susceptibility pattern of micro-organisms isolated from the palms of students of the Obafemi Awolowo University in Ile-Ife, Osun, Nigeria.

Methods: A combination of qualitative and quantitative methods was used to retrieve data. A self-administered questionnaire was utilised to gather socio-demographic characteristics and the practice scale of handwashing from the respondents. Isolation and identification were carried out by culture-based surveys and biochemical tests. Disk diffusion was used to determine susceptibility.

Results: The majority of respondents were between ages 21–25 years, with 54.3% of them being female. About half of individuals never used an alcohol-based hand sanitiser, while only 4.9% of respondents admitted to always using soap to wash their hands. Presumptive identification of the organisms showed 38.1% of organisms as Staphylococcus epidermidis and 17.58% as Micrococcus spp. None of the antibiotics showed total efficacy. The resistance to chloramphenicol was low, and <50% of the isolates showed resistance to tetracycline, novobiocin, and sulphonamide. Resistance to nalidixic acid was seen in 58.4% of organisms tested, and 77.75% were susceptible to tetracycline.

Conclusion: Instances of improper hand hygiene were high, and this may increase the spread of micro-organisms through hand carriage. High resistance to the antibiotics tested was prevalent. Local trends of antimicrobial resistance must be robustly studied and proper interventions developed.
Scientific publishing in the Republic of Macedonia analysed with artificial intelligence
Authors: Spiroski Mirko , Spiroski Ivo
Published: June 2024

Aim: The aim of this study was to present current scientific publishing activity of the Republic of Macedonia analysed with artificial intelligence.
Methods: This analysis was performed with the artificial intelligence platform www.wizdom.ai during March 18, 2024.
Results: In the Republic of Macedonia, in 2023 were published 770 publications with closed, 432 with bronze, 200 with hybrid, 805 with gold, and 61 with green access. In the same year, a total number of 27,418 citations were recorded, with the biggest number of collaborations with United States. Total number of researchers that have published articles in 2023 was 2,550, with local co-authors of 2,268, and with international co-authors of 1,027.
Conclusion: The power of artificial intelligence for analysis of scientific publishing is very sensitive and can be used with precautions because of the limited electronic availability of scientific data, as well as of the different inclusion and exclusion criteria for analysis.
Pelatihan Pembuatan Yoghurt pada Pondok Pesantren Raudhatul Madinah Di Desa Mojorejo Kecamatan Junrejo Kota Batu
Authors: Chrisnandari Rosita Dwi , Dwina Moentamaria  , Achmad Chumaidi  , Luchis Rubianto  , Sigit Udjiana
Published: June 2024

Pondok Pesantren (ponpes) Raudhatul Madinah merupakan salah satu pondok pesantren di Jawa Timur yang menerapkan pembelajaran pesantren berbasis wirausaha.. Oleh karena pondok pesantren Raudhatul Madinah memiliki konsep sebagai pesantren wisata berbasis wirausaha, maka dalam proses pembelajaran santrinya diberikan materi-materi terkait wirausaha. Yoghurt merupakan produk olahan susu yang berasal dari sapi, kambing atau domba. Pada beberapa dekade terakhir, yoghurt adalah produk olahan susu yang popular selain daripada keju dan mulai banyak dijadikan produk wirausaha. Keunggulan Kota Batu sebagai daerah penghasil susu yang juga berdekatan dengan lokasi ponpes, turut mendukung kewirausahaan yang berkaitan dengan yoghurt. Dalam pembuatan produk yoghurt tentunya dibutuhkan pengetahuan-pengetahuan dasar, metode serta teknik pembuatannya, sehingga bimbingan teknis atau pelatihan yang menunjang untuk pembuatan produk yoghurt sangat dibutuhkan di ponpes Raudhatul Madinah. Tujuan pengabdian ini adalah untuk memberikan pelatihan kepada santri pondok pesantren untuk mengolah susu segar menjadi yoghurt yang bisa dijadikan produk wirausaha. Metode yang diterapkan adalah penyuluhan dan pelatihan pembuatan yoghurt. Penyuluhan dilakukan untuk menjelaskan tahapan-tahapan pembuatan yoghurt beserta teori fermentasi pada yoghurt. Pelatihan pembuatan yoghurt dilakuan sebagai implementasi nyata pengolahan susu segar menjadi produk yang lebih bervariasi dan memiliki nilai ekonomis. Hasil kegiatan pengabdian diharapkan mampu memberikan wawasan dan keterampilan kepada santri pondok pesantren untuk menghasilkan minuman yoghurt yang mampu dijadikan produk wirausaha.
Perancangan Dan Peletakan Papan Elektronik Running Teks Sebagai Media Informasi Display Produk Anyaman Bambu di Desa Duwet Kecamatan Tumpang Kabupaten Malang
Authors: Putra Prima Arhandi  , Batubulan Kadek Suarjuna , Retno Damayanti  , Arief Prasetyo  , Banni Satria Andoko  , Eka Larasati Amalia
Published: June 2024

Inovasi produk merupakan salah satu dampak dari pesatnya perubahan teknologi dan keragaman produk dalam menentukan kinerja organisasi. Tingginya inovasi, baik inovasi proses maupun inovasi produk dapat meningkatkan kemampuan perusahaan untuk menciptakan produk yang berkualitas. Kegiatan Kelompok Pengrajin Anyaman Bambu Desa Duwet merupakan jenis usaha baru yang harus dikelola dengan baik serta didukung oleh inovasi produk dan produk yang berkualitas agar memiliki daya saing dan mampu meningkatkan penjualan. Kelompok pengrajin anyaman bambu mengalami kesulitan dalam mengembangkan produk dan sumber daya yang dimiliki belum mempunyai keterampilan, pengetahuan untuk melakukan inovasi produk dan menghasilkan produk yang berkualitas sehingga omzet penjualan masih rendah. Tujuan pengabdian adalah memberikan pelatihan dan pendampingan pembuatan inovasi produk meliputi membuat produk baru dan meningkatkan kualitas produk untuk meningkatkan penjualan anyaman bambu. Metode yang digunakan yaitu dengan pembekalan, workshop, praktek dimana pengusul akan berkolaborasi dengan tenaga ahli di bidang seni kerajinan anyaman bambu, serta mengembangkan website yang sudah dibuat tahun sebelumnya untuk menampilkan (submit) hasil pelatihan pembuatan inovasi produk yang berkualitas kedalam website sebagai keterbaruan produk anyaman bambu yang dihasilkan.
Instalasi Panel Surya Di Masjid Imam Bonjol Di Beringin Bandung 10 Rejosari Sukun Malang
Authors: Mochammad Junus  , Septriandi Wirayoga  , Adzikirani  , Rieke Adrati Wijayanti  , Dianty Marya  , Rizky Ardiansyah
Published: June 2024

Salah satu permasalahan di masyarakat adalah belum dimanfaatan energy alternatif matahari, dan kendala semakin terbatasnya energi listrik PLN, perlu energy alternatif. Oleh karena itu penulis mengupayakan Pemasangan Solar Cell sebagai pembangkit listrik (PLTS), yaitu merupakan sistem pembangkit listrik alternative yang dapat dipasang dimana saja di area terbuka dengan memanfaatkan sinar matahari. Hal ini diharapkan dapat menjadi solusi untuk beban berupa, pompa air, setrika, kipas angina maupun lampu penerangan. Solar cell merupakan salah satu sumber penghasil energi listrik, dari radiasi sinar matahari yang tidak terbatas dan ramah lingkungan. Baterai adalah salah satu pilihan yang dapat menyimpan energi listrik, yang berasal dari panel surya. Dalam pengamatan, baterai diisi oleh panel surya yang menghasilkan tegangan dengan cara mengkonversikan energi matahari menjadi energi listrik. Tegangan yang dihasilkan dari panel surya berkisar 14,8-17,5volt DC. Solar cell yang digunakan dari jenis Polikristal (Poly-crystalline) daya 200wp. Hasil pengukuran memperlihatkan bahwa, distribusi arus dan tegangan dari panel surya, rata-rata sebesar ± 17V, penditribusian ke baterai diatur oleh solar charger controller (SCC), sangat stabil rata-rata 13,5V. Perubahan tegangan DC to AC digunakan Inverter, untuk pensuplay listrik ke pompa air. Hal ini memperlihatkan bahwa setelah baterai terisi selama 2-3 jam, maka baterai mampu beroperasi selama 3 jam dengan tegangan output inverter sebesar 220-176volt AC. Tegangan dan arus akan mulai meningkat pada pagi hari pukul 07.00WIB, kemudian akan mencapai level yang maksimum pada siang hari pukul 10.00-13.00 WIB, dan mulai turun hingga sore hari. Dan untuk target pemanfaatan sistem adalah Masjid Imam Bonjol di Jl. Bandung Rejosari Sukun Malang.
 
Kata kunci— panel surya, radiasi sinar matahari, inverter, baterai.
Pembuatan Company Profile UMKM SISTIAR Singosari
Authors: Rosiani Ulla Delfana , Ariadi Retno Tri H  , Dwi  Puspitasari  , Atiqah Nurul Asri  , Mungki Astiningrum  , Ely Setyo Astuti
Published: June 2024

UMKM SISTIAR adalah salah satu industri rumahan yang ada di Malang yang telah memiliki NIB (Nomor Induk Berusaha) SPP PIRT HKI dan sertifikat Halal yang menghasilkan produk berupa minuman dan makanan ringan khas Malang. Selama ini UMKM SISTIAR menjual produknya di beberapa outlCompany Profile, video, media promosiet di Malang seperti Malang Strudle dan melakukan promosi melalui Whatss App, Face Book, Instagram, Shopee, dan Tokopedia. Namun penjualan produk dirasakan masih kurang dari harapan pemilik usaha. Oleh karena itu dibuatkan video Company Profile sebagai media promosi yang berupa video interaktif yang menarik agar pengguna dan pelanggan bisa mengetahui lebih jelas tentang usaha dari UMKM SISTIAR dan pemilik usaha bisa mendapatkan lebih banyak pembeli baru. Company Profile UMKM SISTIAR ini dibuat dengan video interaktif oleh mahasiswa dan dosen Politeknik Negeri Malang Jurusan Teknologi Informasi. Video ini bercerita tentang apa saja produk yang ada dan bagaimana proses pembuatannya. Diharapkan dengan adanya video company profile ini dapat meningkatkan produksi dan penjualan dari UMKM SISTIAR.
Implementasi Smart Pju Wilayah RT. 05 RW. 08 Kelurahan Mojolangu Kota Malang
Authors: Hariz Santoso Asfari , Imron Ridzki  , Rhezal Agung Ananto  , Hanifiyah Darna Fidya Amaral  , Afidah Zuroida
Published: June 2024

Wilayah RT. 05 RW. 08 Kelurahan Mojolangu Kecamatan Lowokwaru Kota Malang terdiri dari 60 rumah dan 64 KK dengan panjang jalan lingkungan 554 m yang sehari-hari digunakan warga untuk beraktifitas sehari-hari, salah satunya akses jalan ke masjid. Akses jalan tersebut memiliki penerangan jalan umum (PJU) yang dikelola secara mandiri oleh warga sekitar, dari pemasangan hingga pengoperasian dan pembiayaannya. Dalam hal ini PJU yang ada pada wilayah ini masih memiliki kekurangan dalam instalasi dan pengoperasiaanya. Dari segi instalasi hanya terdiri dari supplai sumber listrik yang dimiliki warga, peralatan pemutus tenaga MCB, kabel penghantar, dan lampu. MCB yang digunakan sebagai alat pengoperasian PJU dioperasikan secara manual dan hanya ditempatkan pada tiang yang ditutup oleh kaleng bekas biskuit Solusi yang ditawarkan adalah dengan melaksanakan bimbingan teknis pada warga di wilayah mitra serta implementasi smart system control PJU yang ditujukan agar instalasi PJU di wilayah mitra andal dan aman serta mendorong teraplikasikannya hasil kajian ilmu teknik elektro. Smart system control PJU terdiri dari MCB, timer, kontaktor, dan penghantar yang ditempatkan dalam box panel.Sistem tersebut bekerja dengan memberikan perintah PJU menyala secara umum pukul 17.00 WIB sampai 05.30 WIB dan memberi perintah PJU padam secara otomatis pukul 05.30 WIB sampai pukul 17.00 WIB.
The rehabilitation efficacy of diaphragmatic breathing combined with limb coordination training for lower limb lymphedema following gynecologic cancer surgery
Authors: Wang Jingxin , Ma Jiahui , Zhang Yujie , Tian Yuan , Wang Xinxin , Wang Yu , Xiang Dongquan , Wang Daoyu , Huang Kun , Mao Luxi , Zhang Jiaxin , Fan Huixuan , Li Yilan
Published: June 2024

Objective

To investigate the impact of diaphragmatic breathing combined with limb training on lower limb lymphedema following surgery for gynecological cancer.

Methods

From January 2022 to May 2022, 60 patients with lower limb lymphedema post-gynecologic cancer surgery were chosen. They were split into a control group (n = 30) and a treatment group (n = 30). The control group underwent complex decongestive therapy (CDT) for managing lower limb lymphedema after gynecologic cancer surgery, while the treatment group received diaphragmatic breathing combined with limb coordination training alongside CDT. Both groups completed a 4-week treatment regimen. The lower limb lymphedema symptoms were evaluated using the genital, lower limb, buttock, and abdomen (GCLQ) scores; bilateral lower limb circumference measurements; and anxiety and depression scores.

Results

Compared to sole CDT administration, individuals undergoing diaphragmatic breathing coupled with limb coordination training experienced notable reductions in scores for the self-perceived symptom assessment questionnaire (GCLQ), bilateral lower limb circumference, as well as anxiety and depression scores.

Conclusion

The incorporation of diaphragmatic breathing combined withalongside limb coordination training can accelerate and augment the efficacy of treating lower limb lymphedema post-gynecologic cancer surgery.
In vivo and in silico studies of the effects of oil extracted from Cannabis sativa L. seeds on healing of burned skin wounds in rats
Authors: Bouarfa Mouna , Chebaibi Mohamed , Ez-Zahra Amrati Fatima , Souirti Zouhair , Saghrouchni Hamza , El atki Yassine , Bekkouche Khalid , Mourabiti Hajar , Bari Amina , Giesy John P. , Mohany Mohamed , Al-Rejaie Salim S. , Aboul-Soud Mourad A. M. , Bousta Dalila
Published: June 2024

Introduction

This study investigates the potential effects of cannabis seed oil (CSO) on the wound healing process. The aim was to assess the efficacy of CSO in treating skin wounds using an animal model and to explore its anti-inflammatory properties through in silico analysis.

Methods

Eighteen male albino Wistar rats, weighing between 200 and 250 g, were divided into three groups: an untreated negative control group, a group treated with the reference drug silver sulfadiazine (SSD) (0.01 g/mL), and a group treated topically with CSO (0.962 g/mL). The initial wound diameter for all groups was 1 cm. In silico studies were conducted using Maestro 11.5 to evaluate the anti-inflammatory effects of phytoconstituents against cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2).

Results

CSO and SSD treatments led to a significant reduction (p <0.05) in the size of burned skin wounds by day 5, with contraction rates of 53.95% and 45.94%, respectively, compared to the untreated negative control group. By day 15, wounds treated with CSO and SSD had nearly healed, showing contraction rates of 98.8% and 98.15%, respectively. By day 20, the wounds treated with CSO had fully healed (100%), while those treated with SSD had almost completely healed, with a contraction rate of 98.97%. Histological examination revealed granulated tissue, neo-blood vessels, fibroblasts, and collagen fibers in wounds treated with CSO. In silico studies identified arachidic acid, γ-linolenic acid, and linolenic acid as potent inhibitors of COX-1 and COX-2. Serum biochemical parameters indicated no significant changes (p > 0.05) in liver and kidney function in rats treated with CSO, whereas a significant increase (p < 0.01) in ALAT level was observed in rats treated with SSD.

Discussion

The findings demonstrate that CSO has a promising effect on wound healing. The CSO treatment resulted in significant wound contraction and histological improvements, with no adverse effects on liver and kidney function.However, the study's limitations, including the small sample size and the need for detailed elucidation of CSO's mechanism of action, suggest that further research is necessary. Future studies should focus on exploring the molecular pathways and signaling processes involved in CSO’s pharmacological effects.
Early immune response to Toxoplasma gondii lineage III isolates of different virulence phenotype
Authors: Uzelac Aleksandra , Klun Ivana , Djurković-Djaković Olgica
Published: June 2024

Introduction

Toxoplasma gondii is an intracellular parasite of importance to human and veterinary health. The structure and diversity of the genotype population of T. gondii varies considerably with respect to geography, but three lineages, type I, II and III, are distributed globally. Lineage III genotypes are the least well characterized in terms of biology, host immunity and virulence. Once a host is infected with T.gondii, innate immune mechanisms are engaged to reduce the parasite burden in tissues and create a pro-inflammatory environment in which the TH1 response develops to ensure survival. This study investigated the early cellular immune response of Swiss-Webster mice post intraperitoneal infection with 10 tachyzoites of four distinct non-clonal genotypes of lineage III and a local isolate of ToxoDB#1. The virulence phenotype, cumulative mortality (CM) and allele profiles of ROP5, ROP16, ROP18 and GRA15 were published previously.

Methods

Parasite dissemination in different tissues was analyzed by real-time PCR and relative expression levels of IFNγ, IL12-p40, IL-10 and TBX21 in the cervical lymph nodes (CLN), brain and spleen were calculated using the ΔΔCt method. Stage conversion was determined by detection of the BAG1 transcript in the brain.

Results

Tissue dissemination depends on the virulence phenotype but not CM, while the TBX21 and cytokine levels and kinetics correlate better with CM than virulence phenotype. The earliest detection of BAG1 was seven days post infection. Only infection with the genotype of high CM (69.4%) was associated with high T-bet levels in the CLN 24 h and high systemic IFNγ expression which was sustained over the first week, while infection with genotypes of lower CM (38.8%, 10.7% and 6.8%) is characterized by down-regulation and/or low systemic levels of IFNγ. The response intensity, as assessed by cytokine levels, to the genotype of high CM wanes over time, while it increases gradually to genotypes of lower CM.

Discussion

The results point to the conclusion that the immune response is not correlated with the virulence phenotype and/or allele profile, but an early onset, intense pro-inflammatory response is characteristic of genotypes with high CM. Additionally, high IFNγ level in the brain may hamper stage conversion.
Hypersynchrony in sarcomeric hypertrophic cardiomyopathy: description and mechanistic approach using multimodal electro-mechanical non-invasive cartography (HSYNC study)
Authors: Réant Patricia , Bonnet Guillaume , Dubé Frédérique , Massie Charles , Reynaud Amélie , Michaud Matthieu , Duchateau Josselin , Lafitte Stéphane
Published: June 2024

Background

Little is known about left ventricular (LV) sequences of contraction and electrical activation in hypertrophic cardiomyopathy (HCM). A better understanding of the underlying relation between mechanical and electrical activation may allow the identification of predictive response criteria to right ventricular DDD pacing in obstructive patients.

Objective

To describe LV mechanical and electrical activation sequences in HCM patients compared to controls.

Materials and methods

We prospectively studied, in 40 HCM patients (20 obstructive and 20 non-obstructive) and 20 healthy controls: (1) mechanical activation using echocardiography at rest and cardiac magnetic resonance imaging, (2) electrical activation using 3-dimensional electrocardiographic mapping (ECM).

Results

In echocardiography, healthy controls had a physiological apex-to-base delay (ABD) during contraction (23.8 ± 16.2 ms). Among the 40 HCM patients, 18 HCM patients presented a loss of this ABD (<10 ms, defining hypersynchrony) more frequently than controls (45% vs. 5%, p = 0.017). These patients had a lower LV end-diastolic volume (71.4 ± 9.7 ml/m2 vs. 82.4 ± 14.8 ml/m2, p = 0.01), lower native T1 values (988 ± 32 ms vs. 1,028 ± 39 ms, p = 0.001) and tended to have lower LV mass (80.7 ± 23.7 g/m2 vs. 94.5 ± 25.3 g/m2, p = 0.08) compared with HCM patients that had a physiological contraction sequence. There was no significant relation between ABD and LV outflow tract obstruction. While HCM patients with a physiological contraction sequence presented an ECM close to those encountered in controls, patients with a loss of ABD presented a particular pattern of ECM with the first potential more frequently occurring in the postero-basal region.

Conclusion

The LV contraction sequence can be modified in HCM patients, with a loss of the physiological ABD, and is associated with smaller LV dimensions and a particular pattern of ECM. Further research is needed to determine whether this pattern is related to an electrical substrate or is the consequence of the hypertrophied heart's specific geometry.

Clinical trial registration

ClinicalTrial.gov: NCT02559726.
Lung transplantation following controlled hypothermic storage with a portable lung preservation device: first multicenter European experience
Authors: Provoost An-Lies , Novysedlak Rene , Van Raemdonck Dirk , Van Slambrouck Jan , Prisciandaro Elena , Vandervelde Christelle M. , Barbarossa Annalisa , Jin Xin , Denaux Karen , De Leyn Paul , Van Veer Hans , Depypere Lieven , Jansen Yanina , Pirenne Jacques , Neyrinck Arne , Bouneb Sofian , Ingels Catherine , Jacobs Bart , Godinas Laurent , De Sadeleer Laurens , Vos Robin , Svorcova Monika , Vajter Jaromir , Kolarik Jan , Tavandzis Janis , Havlin Jan , Ozaniak Strizova Zuzana , Pozniak Jiri , Simonek Jan , Vachtenheim Jiri , Lischke Robert , Ceulemans Laurens J.
Published: June 2024

Introduction

Compared with traditional static ice storage, controlled hypothermic storage (CHS) at 4–10°C may attenuate cold-induced lung injury between procurement and implantation. In this study, we describe the first European lung transplant (LTx) experience with a portable CHS device.

Methods

A prospective observational study was conducted of all consecutively performed LTx following CHS (11 November 2022 and 31 January 2024) at two European high-volume centers. The LUNGguard device was used for CHS. The preservation details, total ischemic time, and early postoperative outcomes are described. The data are presented as median (range: minimum–maximum) values.

Results

A total of 36 patients underwent LTx (i.e., 33 bilateral, 2 single LTx, and 1 lobar). The median age was 61 (15–68) years; 58% of the patients were male; 28% of the transplantations had high-urgency status; and 22% were indicated as donation after circulatory death. In 47% of the patients, extracorporeal membrane oxygenation (ECMO) was used for perioperative support. The indications for using the CHS device were overnight bridging (n = 26), remote procurement (n = 4), rescue allocation (n = 2), logistics (n = 2), feasibility (n = 1), and extended-criteria donor (n = 1). The CHS temperature was 6.5°C (3.7°C–9.3°C). The preservation times were 11 h 18 (2 h 42–17 h 9) and 13 h 40 (4 h 5–19 h 36) for the first and second implanted lungs, respectively, whereas the total ischemic times were 13 h 38 (4 h 51–19 h 44) and 15 h 41 (5 h 54–22 h 48), respectively. The primary graft dysfunction grade 3 (PGD3) incidence rates were 33.3% within 72 h and 2.8% at 72 h. Intensive care unit stay was 8 (4–62) days, and the hospital stay was 28 (13–87) days. At the last follow-up [139 (7–446) days], three patients were still hospitalized. One patient died on postoperative day 7 due to ECMO failure. In-hospital Clavien–Dindo complications of 3b were observed in six (17%) patients, and 4a in seven (19%).

Conclusion

CHS seems safe and feasible despite the high-risk recipient and donor profiles, as well as extended preservation times. PGD3 at 72 h was observed in 2.8% of the patients. This technology could postpone LTx to daytime working hours. Larger cohorts and longer-term outcomes are required to confirm these observations.
Clinical experiences of intervention of neurodevelopmental disorders and difficulties in school learning from historical-cultural neuropsychology
Authors: Bonilla-Sánchez María del Rosario
Published: June 2024

Cultural–historical (CH) neuropsychology proposes the qualitative analysis of neurodevelopmental disorders and learning difficulties through the identification of the neuropsychological factor (NF) that underlies the symptoms and difficulties that arise in cognition and academic performance. The objective of this study is to present clinical experiences of the neuropsychological intervention of unique cases of varying degrees of initial education. Qualitative assessment is a process that reveals the strengths and weaknesses in child development, as well as the possibilities of what children will be able to do for themselves. It assesses their zone of proximal development, not just the zone of current development. Neurodevelopmental and learning disorders present particular manifestations during life, so a qualitative analysis can account for their subtle changes during the course of life and schooling. The use of the principles of intervention constitutes the methodological axis for the elaboration of the programs; these programs will be shaped according to the needs of the children. The case study strengthens the expertise of clinical knowledge by contributing to the empirical field on the possibilities and proposals of neuropsychological intervention.