bluuebunny/crossref_metadata_2025 huggingface dataset:
In Vitro Anti-Inflammatory Assay of Bitter Melon (Momordica charantia L.) Ethanol Extract
Authors: Rahmawati Rahmawati , Widiastuti Harti , Sulistya Eka
Published: September 2020

Bitter melon contains flavonoids that have anti-inflammatory function. Inflammation can be caused by protein denaturation. This research tested the anti-inflammatory potential of ethanol extract of leaves and bitter melon (Momordica charantia L.) using a UV-Vis spectrophotometer and protein denaturation inhibition method. There were three experimental groups formed in this research including negative control group, positive control group, and test solutions. Diclofenac sodium was used in the positive control group at concentration series of 1, 2, 4, 8, and 16 ppm, obtaining a regression equation Y = 3.546X + 2.163 and r = 0.9990. Whilst, for bitter melon ethanol extract at a series of concentrations of 10, 20, 40, 80 and 160 ppm obtained a regression equation Y = 0.243X + 11.74 and r = 0.9995. The potential of diclofenac sodium as an anti-inflammatory agent was shown by IC50 of 13.490 µg / mL, while the ethanol extract of bitter melon fruit has an IC50 of 157.448 µg / mL. This result indicated that bitter melon ethanol extract had the potential as moderate anti-inflammatory agent.
Isolation and Identification of Free Radical Scavenging Compound from Stem Bark Soursoup (Annona muricata L.) Extract
Authors: Bafadal Mentarry , Dahlia A Amaliah , Najib Ahmad
Published: September 2020

Isolation and Identification of free radical active compound from stem bark soursoup (Annona muricata L.) extract. The aim of this research is to observe the chemical compound of stem bark the soursoup (A. muricata L.) which is active as a free radical. 550 gram of stem bark the soursoup (A. muricata L.) was by graduate extracted using n-heksan, ethyl acetat and ethanol solvents respectively. Extract result is the extraction, it was produced 2.4 gram n-heksan extract, 8.4 gram ethyl acetat extract, 2.1 gram ethanolic extract. The isolation of ethyl acetat extract was conducted using colom chromatography (TLC) method using eluent n-hexane : ethyl acetat (7:3) and it was produced four fractions. The third fraction was isolated using preparative thin layer chromatography with mob ile phase n-hexane : ethyl acetat (6:1) and got 2 bands. The isolate identified by UV-Vis spectroscopy, IR spectroscopy and analyzed by chemistry reaction. From the data result show that isolate is acetogenin.
The Economic Crisis Seen from Israel: Cause and Effect
Authors: Polliack Lily
Published: September 2020

Put it briefly, the current economic crisis, primarily affecting the Western world, is the direct consequence of the United States of America’s strategic approach to Middle East conflict resolution, mostly as conducted at the time of the two Bush Administrations, 1988-1992 and 2001-2009. It begins in the summer of 1990, when President George Bush amassed in Saudi Arabia an army of half a million US soldiers who took over the capital – American style. While the US military goal was to prepare there for an offensive intended to oust Saddam Hussein from Kuwait and, if possible, Iraq, the Muslims living in Riyadh considered American social behavior in their city to be offensive to the Muslim way of life. Hence it created an anti-American sentiment that ultimately paved the way for a vanguard of Islamic Fundamentalists to carry out 9/11. Their intention was to oust Western influence from the Middle East, but instead of getting the message, the son of President George Bush went after them, seeking to stamp Islamic Fundamentalism out of Afghanistan, Iraq, Pakistan, Yemen, etc.
Past, Present and Future of Social Democracy: The Debate (?) in Italy and the Nordic Experience
Authors: Quirico Monica
Published: September 2020

Does a debate on Social Democracy – its history, its present state, and its future perspectives – exist today in Italy? This is the very first question that one wonders about, when analysing the Italian contributions on such a political tradition, as they are few and not particularly innovative. Such a paucity can be explained by the weak “rootedness” of this political tradition in Italian history, due to the existence, until 1991, of a strong communist party (PCI), which identified in Democratic Socialism one of its main enemies. But what about the following developments of the communist party, which became first PDS, Democratic Party of the Left, then DS, Democrats of the Left, and finally PD, Democratic Party)? Was the leadership – who, in spite of all the changes in the party name, has remained more or less the same – moved by the fall of the Berlin wall to approach Democratic Socialism?
Compensating the Crashers
Authors: Arnarsson Ársæll Már
Published: September 2020

As soon as the dust began to settle after the greatest economic crisis since 1929, the very first thing to surface in the field of finance was greed. Unabated, shameless, and, what is more, the very thing that had caused the whole system to topple in the first place. In this article I will briefly discuss executive pay-structure and how it can actually work against the company’s interest, as well as try to identify the reasons why companies choose to maintain this seemingly unsuitable structure.
The Effect of Problem Based Learning Model on Students Mathematic Representation Ability and Student Adversity Quotient at SD Islam Setia Nurul Azmi Medan
Authors: Fadillah Siti , Amin Fauzi Kms. Muhammad , Yus Anita
Published: September 2020

This study aims to determine: (1) how much influence the problem-based learning model has on students' mathematical representation abilities, (2) how much influence is the problem based learning model on students' adversity quotient, 3) whether there is an interaction between the learning model and KAM on students' representation abilities, (4) whether there is an interaction between the learning model and KAM on students' adversity quotient, and (5) how to analyze students' mathematical representation abilities seen from the indicators. This research is about quasi-experimental research. The population of this study was all fourth grade students of SD Islam Setia Nurul Azmi Medan in the academic year 2020/2021 which consisted of four classes. Samples were selected by random sample of two classes. The instruments used were the representation ability test and the attitude scale adversity quotient. The data obtained was then analyzed using ANACOVA and ANAVA in the SPSS 20 program. The results showed: 1) the magnitude influence of the PBL model on the mathematical representation ability of 0.931 or 93.1%, 2) the magnitude influence of the PBL model on the adversity quotient is 0.967 or 96.7%, 3) there is an interaction between the initial ability and PBL learning to the mathematical representation ability of students with an Fcount of 3.906 so that Ha is accepted and H0 is rejected, 4) there is no interaction between the initial ability and learning PBL to the adversity quotient for students with an Fcount of 0.198 so that H0 is accepted, 5) the ability of the student's visual representation indicator is high with an average score in the experimental class 76 and the control class 72, the ability of the student's visual representation indicator is high with an average score in the experimental class 72 and the control class 68, The indicator ability of the students' representation of words or written text was moderate with the average score in the experimental class 65 and the control class 61.
The Development of Learning Instrument Using Problem Based Learning Model to Improve Critical Thinking of Junior High School Students
Authors: Nasution1 Yusrina Santri , Syahputra Edi , Mulyono Mulyono
Published: September 2020

The study aims to: (1) determine the validity and effectiveness of learning instrumentswhich are developed, (2) determine the increase of critical thinking skills of student using learning instruments developed. This research is development research. The Development model used is 4-D model which consists of four stages: defining, designing, development and disseminate. The results of the defining phase are used to design a learning instrument, thenthis draft is validated and tested in the classto see its effectiveness. From this development, result obtained are: (1) The learning instrument developed is valid with an average validity total of lesson plan = 4.35, student books = 4.35, student worksheet = 4.36; (2) The learning instrumentis effective, that can be seen from both the individual and classical learning mastery are achieved, student activities within the specified tolerance limits and the student’s response toward learning instruments are in good categories; (3) the increasing average of critical thinking skills of students from first trial test to second trial test is 0.20 points.
Pengaruh Debt to Equity Ratio, Firm Size dan Working Capital terhadap Return on Asset pada Perusahaan Property and Real Estate yang terdaftar di Bursa Efek Indonesia
Authors: Felicia Diana , Margareth Sherlyn , Rani Rani , Simorangkir Enda Noviyanti
Published: September 2020

This study aims to determine if the independent variables affects dependent variable on Property and Real Estate companies on the Indonesia Stock Exchange from January to December in the period of 2015-2017. Where the independent variables are Debt to Equity Ratio, Firm Size and Working Capital. Whereas, the dependent variable is  Return on Asset. Where there are as many as 46 Property and Real Estate companies listed on the Indonesia Stock Exchange. However, the samples are examined only 35 companies in accordance with the desired criteria. This research method uses multiple linear regression analyses with the aid of SPSS 19. The results of this analysis shows in the period of 2015-2017 there is a Property and Real Estate company that on the T test Debt to Equity Ratio is partially no effect on Return On Asset, Firm Size in partial no significant effect on Return on Asset and Working Capital also partial no significant effect on Return on Asset. However, on the F test Debt to Equity Ratio, Firm Size and Working Capital simultaneously have significant effect on Return on Asset. Adjusted R Square at 0,110 or 11% which means that 11% variable Return on Asset were influenced by Debt to Equity Ratio, Firm Size and Working Capital while (100%-11%) 89% of its unexplained variable.
Perceptions of violence based on genetics: the influence of monoamine oxidase A in the origin of violent behavior
Authors: Mouta Alba Angélica Nunes , De Carvalho Lays Carollinne Soares , De Oliveira Eduardo Ferreira , Martins Daniela Moura Parente , Morais Isadora Maria de Almeida , De Souza Stefen Kesse Matos , Nogueira Francisco Jander de Sousa , Da Silva Augusto César Beltrão , Almendra Neto Oswaldo Lima , Barboza Danielle Lais Lopes , Beltrão Renata Paula Lima
Published: September 2020

Objective: To gather scientific literature regarding the influence of the low activity of the enzyme Monoaminoxidase A, responsible for the regulation of brain neurotransmitters, on criminal and / or violent behavior. Methods: Searches were performed in the PubMed and SCOPUS databases using “genes”, “crime” and “monoaminoxidase”, selecting articles published between 2009 and 2019. Results: The selected sample, after applying the inclusion criteria and exclusion, was composed of 14 articles. Discussion: A relationship was found between low levels of activity of Monoaminoxidase A, when associated with socio-environmental factors, with a greater tendency to commit criminal and / or violent acts. Among the socio-environmental factors, the most cited is the experience of trauma in childhood. However, there were copyright disagreements, which demonstrates the need for further investigation and development of studies on the subject. Final considerations: It was found that individuals with low Monoaminoxidase A activity and who experienced stressful socioenvironmental factors are more prone to aggressive and / or violent behavior.
Perfil socioeconômico de tutores e proposição de avaliação do bem-estar em muares de tração extratores de areia no Rio Paraíba
Authors: Ribeiro Alvaro Augusto Ramos , Fonseca Lucas Santana da , Amorim Claudia Vívian de Oliveira , Graboschii Amanda Caroline Gomes , Vargas Yana Gabriella de Morais , Felix Ana Paula Menezes , Escodro Pierre Barnabé , Mariz Tobyas Maia de Albuquerque
Published: September 2020

Na cidade de Viçosa, estado de Alagoas, muitos muares são utilizados para retirada de areia do rio Paraíba, fornecendo aos comércios de materiais de construção da região e auxiliando no combate ao assoreamento no leito do rio sendo constantemente enquadrados nessa discussão dicotômica entre sustentabilidade humana e maus tratos animais. A pesquisa tratada neste trabalho foi realizada em duas etapas utilizando dados de 13 tutores e seus muares trabalhadores na extração de areia do rio paraíba, avaliando através de questionario pré estruturado o perfil socioeconômico dos tutores e também o bem estar dos muares através da avaliação sorológica e paramétrica utilizando como base parâmetros pré estabelecidos como Frequência Cardíaca (FC), Escore Corporal (EC), níveis de estresse muscular, presença de dor e claudicação e presença de feridas. Em relação a problemática, o Projeto Pró-Carroceiros da Universidade Federal de Alagoas realiza, há uma década, atividades trimestrais de conscientização aos tutores em relação ao bem-estar animal, além de atividades assistenciais veterinárias, como vacinação, desverminação, exames de sangue e atendimentos clínicos. O artigo objetiva traçar o perfil socioeconômico dos tutores e propor um modelo de avaliação do bem-estar desses animais, a partir das atividades extensionistas e de pesquisa integradas.
Ensaio narrativo sobre processo de enlutamento frente a covid-19
Authors: Mauricio de Souza Neto Olavo , Azevedo dos Reis Maria Luiza , Alexandrino Arthur , Agra Glenda
Published: September 2020

Objetivo: Explanar acerca do processo de enlutamento frente à COVID-19. Método: Trata-se de uma revisão narrativa da literatura sobre o processo de enlutamento frente à pandemia da COVID-19. Resultados: Foram apresentados quatro eixos condutores sobre a temática, a saber: processo de luto: compreensão do diagnóstico de luto; transtorno de luto complexo persistente; luto no contexto da COVID-19: estratégias de suporte e apoio emocional no enlutamento durante a pandemia da COVID-19. Conclusão: O luto é um processo normativo de adaptações às perdas, abrangendo emoções, condições, sensações físicas e mudanças comportamentais, exigindo dos profissionais de saúde atenção à escuta, acolhimento e observação de sinais clínicos e psíquicos de sofrimento mental.
Resistance training with and without insulin administration: an analysis of the cardiac plexus and epicardial adipose tissue
Authors: Jimenes Diogo Rodrigues , Pereira Victor Augusto Roncaglia , Pereira Andréia Vieira , Pedrosa Maria Montserrat Diaz , Berti Jairo Augusto , Sant’Ana Débora de Mello Gonçales , Barbosa Carmem Patrícia
Published: September 2020

The cardiac plexus is a vast network of neurons grouped into ganglia distributed throughout the myocardium. The epicardial adipose tissue covers the heart performing important functions, such as, lipid storage. However, its exaggerated expression might represent a risk factor, which can be prevented by the practice of physical activities that improves the heart contractile propulsive capacity. Insulin has been used in association with physical exercise so as to increase muscle mass and improve physical performance. Both insulin and exercise have been evidenced due to their neurotrophic effects. The purpose of this study was to ascertain whether insulin associated with resistance training could structurally modify the cardiac plexus and epicardial adipose tissue. Four groups (n = 6) of male Swiss mice were used: non-trained saline, non-trained insulin; trained saline; trained insulin. The training was performed on a vertical ladder at 90% of the maximum load, 3 times/week for 8 consecutive weeks. After the experimental period, the hearts of the animals were removed, and 5-μm sections were stained with Hematoxylin/Eosin, Giemsa and Picrossirius in order to evaluate the structures of the cardiac plexus. There was no significant difference with regard to the area and the total number of neurons, nor to the area with collagen. However, whereas insulin administration hypertrophied the adipocytes and predisposed an inflammatory environment, physical exercise played an anti-inflammatory role. As a conclusion, it is worth mentioning that resistance training did not change the cardiac plexus, however the epicardial adipose tissue was reduced, an effect antagonized by insulin.
A evolução da Teoria do Cuidado Humano para a Ciência do Cuidado Unitário
Authors: Tonin Luana , Lacerda Maria Ribeiro , Favero Luciane , Nascimento Jaqueline Dias do , Denipote Adelita Gonzalez Martinez , Gomes Ingrid Meireles
Published: September 2020

A Teoria do Cuidado Humano ou Ciência do Cuidado Unitário é usada mundialmente e apresenta-se em constante evolução. Ao longo dos anos, junto com a evolução da Teoria ocorreu a evolução dos paradigmas, passando de Fatores Caritativos para Elementos do Processo Clinical Caritas e recentemente, Elementos do Processo Clinical Caritas-Veritas. Objetivo: Apresentar a evolução da Teoria do Cuidado Humano para a Ciência do Cuidado Unitário e as ressonâncias sobre os Elementos do Processo Clinical Caritas-Veritas. Método: Reflexão teórica sobre os aspectos conceituais e os princípios da Teoria do Cuidado Humano e a evolução/mudança dos paradigmas para a Ciência do Cuidado Unitário. Resultados: Uma ênfase especial é dada sobre os Elementos do Processo Clinical Caritas na perspectiva Caritas-Veritas. Estes aspectos nucleares dos conceitos são desenvolvidos na fundamentação filosófica e ética do corpo da Ciência do Cuidado Unitário.  Considerações finais: Acredita-se que este manuscrito poderá servir como um esquema disciplinar primário para a prática profissional de enfermeiros ao utilizar a Ciência do Cuidado Unitário.
Parâmetros bromatológicos e fermentativos da silagem de capim elefante aditivado com subproduto de cupuaçu
Authors: Lerner Lerner Arévalo , Oliveira Palloma , Soares Firmino Salenilda , Ribeiro Angelita Alecchandra , Cunha dos Santos Betina Raquel , Souza Amorim Dayana , Gonzalez Chacón Salvador , Codognoto Luciane da Cunha
Published: September 2020

O uso de silagens de forrageiras tropicais é mais uma alternativa para minimizar a escassez de forragem no período seco, dentre as forrageiras que podem ser adotadas o capim elefante merece destaque. Nesse contexto, o objetivo do trabalho foi avaliar os aspectos bromatológicos e qualidade fermentativa de silagem de capim elefante aditivada com torta de semente de cupuaçu. O experimento foi realizado em delineamento inteiramente casualizado com cinco tratamentos e quatro repetições, denominados de: SCE= 100% silagem de capim elefante puro; STC20 = silagem 80% capim elefante + 20% de torta de cupuaçu; STC40 = silagem 60% capim elefante + 40% de torta de semente de cupuaçu; STC60 = silagem 40%capim elefante + 60% de torta de semente de cupuaçu e STC80 = silagem 20%  capim elefante + 80% de torta de semente de cupuaçu. Foram utilizados silos de PVC com 50 cm de comprimento, 10 cm de diâmetro e capacidade de 3,5kg, após 60 dias de fermentação os silos foram abertos, pesados novamente, homogeneizadas e retiradas amostras para determinar os teores de: MS, PB, FDN, FDA, MM, EE, CEL, HEM, LIG, MM, NDT, PMS, PE, PG e pH da silagem. Em termos de composição bromatológicas a silagem STC80 foi a que apresentou os melhores resultados, além de diminuir as perdas de MS, as perdas por efluentes e por gases. Portanto, recomenda-se a inclusão de 80% da torta de semente de cupuaçu na silagem com capim elefante, por melhorar o perfil fermentativo e a composição bromatológica da silagem.
Palavras-chave: Conservação; Períodos críticos; Forragens; Pennisetum purpureum; Estratégias.
A prática do quarto e quinto passos da Iniciativa Hospital Amigo da Criança
Authors: Santos Floriacy Stabnow , Mesquita Antonia Vilquenia  da Silva , Ribeiro Narcisa Gomes , Aragão Francisca Bruna Arruda , Santos Romila Martins de Moura Stabnow , Fontoura Iolanda Graepp , Maciel Sergiane Maia , Santos Neto Marcelino
Published: September 2020

Objetivos: Verificar o cumprimento do quarto e quinto passos da Iniciativa Hospital Amigo da Criança em uma maternidade de referência no nordeste brasileiro. Metodologia: Pesquisa descritiva de natureza quantitativa, realizada entre março e julho de 2019, com 380 puérperas entrevistadas nas enfermarias do hospital para preenchimento de um formulário. Os dados foram tabulados de acordo com as frequências absolutas e relativas. Resultados: Encontrou-se que 17% dos bebês foram colocados para mamar na sala de parto em cumprimento do quarto passo da Iniciativa Hospital Amigo da Criança, 82% das mães receberam auxílio para amamentar em cumprimento do quinto passo; 79% das mães tinham entre 20 a 30 anos, 61% eram pardas, 71% eram casadas, 57% cursaram Ensino Médio, 69% eram donas de casa, 48% com renda entre 1 e 2 salários mínimos, 42% tinha 2 filhos, 54% não tinham residência própria, todas fizeram pré-natal, 66% fizeram mais de 6 consultas, 79% foi orientada sobre amamentação. Conclusão: Os índices encontrados referentes ao quarto e quintos passos da Iniciativa Hospital Amigo da Criança estão abaixo dos recomendados pelo Ministério da Saúde. Esses resultados reforçam a importância da efetivação do apoio e promoção do aleitamento materno como foco da equipe de enfermagem.
Ansiolytic effect of essential oils: a review on pre-clinical and clinical studies
Authors: Oliveira Júlia Assunção de Castro , Karin de Lima Rafaela , Totarelli Monteforte Priscila , Alves Marques Érica , Duarte Coelho Adriane , Losada Gavilanes Manuel , Pereira Zanzini Alice , Lara de Carvalho Alisson
Published: September 2020

Anxiety participates in the body's natural defense, however, it can be pathological, when symptoms start to interfere in the individual's routine, causing loss of quality of life. Essential oils (EOs) are secondary metabolites with numerous pharmacological and biological activities, where we can highlight anxiolytic activity. Thus, the objective was to carry out a systematic review of the last 9 years in the large area of ​​pharmacology and toxicology, and to verify which EOs have anxiolytic activity, which tests were performed and the possible mechanisms involved. A bibliographic review with a qualitative and quantitative nature was carried out, using the Scopus database, where original studies were published, published between January 2010 and August 10, 2019, of the pre-clinical and clinical trial type that present results referring to anxiolytic activity of EOs, excluding those studies that did not understand the area of ​​pharmacology and / or toxicology. At the end of this analysis, of the 71 papers found, 18 were selected to compose this review. This review made it possible to visualize the panorama of preclinical and clinical studies for assessing anxiety with the use of OEs in the last 9 years, pointing out that in addition to the EO of Lavandula angustifolia, other EOs can also be promising, such as the EOs obtained from species of the genus Citrus. However, there is a scarcity of clinical studies to prove the efficacy and safety of the use of these EOs in the treatment of anxiety, which allows the opening of research in this area for the development and launch of new natural anxiolytics.
Recurrence quantification analysis of monthly rainfall time series in Pernambuco, Brazil
Authors: Santana Leika Irabele Tenório de , Silva Antonio Samuel Alves da , Menezes Rômulo Simões Cezar , Stosic Tatijana
Published: September 2020

Precipitation is the main climatic variable that is used for modeling risks indices for natural disasters. We investigated nonlinear dynamics of monthly rainfall temporal series recorded from 1962 to 2012, at three stations in Pernambuco state, Brazil, located in regions with different rainfall regime (Zona da Mata, Agreste and Sertão), provided by the Meteorological Laboratory of the Institute of Technology of Pernambuco (Laboratório de Meteorologia do Instituto de Tecnologia de Pernambuco – LAMEP/ITEP). The objective of this work is to contribute to a better understanding of the spatiotemporal distribution of rainfall in the state of Pernambuco. We use the methodology from nonlinear dynamics theory, Recurrence plot (RP) that allows to distinguish between different types of underlying processes. The results showed that rainfall regime in deep inland semiarid Sertão region is characterized by weaker and less complex deterministic behavior, comparing to Zona da Mata and Agreste, where we identified transitions between chaotic and nonstationary type of dynamics. For transitional Agreste region rainfall dynamics showed stronger memory with longer mean prediction time, while for sub humid Zona da Mata rainfall dynamics is characterized by laminar (slowly changing) states.
Impactos da COVID-19 no trabalho e saúde mental dos trabalhadores da saúde
Authors: Moraes Cruz Roberto , Torrico Grasiela , Knapik Janete , Sepúlveda Sales Synara , Pegoraro Gai Maria Julia , Pereira Labiak Fernanda , Domingos Onofre Adelino , Martins Klokner Sarah Gisele
Published: September 2020

Os impactos globais na saúde pública e na economia provocados pela pandemia da COVID-19 salientaram as fragilidades dos sistemas de preparação para crises e emergências tanto do Estado como das empresas. O trabalho, emprego e renda foram notadamente afetados e a insegurança pelo futuro devido às perdas econômicas, temor pelo contágio, mudanças na rotina e aumento de estressores ambientais afetaram os trabalhadores, especialmente os profissionais da saúde na linha de frente do combate à pandemia. Este artigo se propõe a discutir os impactos da COVID-19 no trabalho e na saúde mental dos trabalhadores da saúde. Para isso, analisou-se a produção do conhecimento mais recente sobre os impactos da COVID-19 no trabalho e renda e sua relação com evidências de sintomas de agravos à saúde mental entre os trabalhadores, em especial os profissionais da saúde. Trata-se de uma revisão integrativa da literatura, lastreada em bases de dados internacionais, relatórios de agências internacionais e legislação pertinente. Os resultados demonstram que a exposição prolongada ao agente patogênico, temor pelo contágio, jornadas de trabalho intensivas, estressores ambientais e ocupacionais, necessidade de lidar com as demandas psicológicas dos pacientes e os dilemas éticos na tomada de decisão tornam os profissionais de saúde susceptíveis a uma perda na qualidade de vida durante e após a pandemia.
Atividades Práticas de Biologia: uma Sequência de Ensino Investigativa sobre o Ciclo Celular
Authors: Lima Michelle Mara de Oliveira , Cardoso Thâmara Chaves , Santos Filho Francisco Soares , Martins Francielle Alline , Almeida Pedro Marcos de
Published: September 2020

O objetivo do estudo foi desenvolver e analisar o uso de uma Sequência de Ensino Investigativa (SEI) sobre o ciclo celular (mitose), composta por um modelo didático e pela prática de Allium cepa L. com estudantes de duas escolas públicas e uma particular em Floriano (PI). Mediante as respostas às problematizações da SEI verificou-se que os estudantes possuíam conhecimentos desconexos e fragmentados quanto ao conteúdo do ciclo celular. A aplicação da SEI modificou a postura dos alunos das três escolas, que passaram a ser mais participativos entre si e com a professora, corroborando com os dados obtidos da comparação dos questionários pré e pós-teste. As metodologias ativas aplicadas foram satisfatórias e tiveram ótima aceitação pelos estudantes. Portanto, constatou-se que o uso da SEI facilitou a compreensão da dinâmica que envolve o ciclo celular e suas implicações para a constituição dos seres vivos, minimizando o distanciamento entre a teoria e a prática.
Empatia e reconhecimento de expressões faciais de emoções básicas e complexas, em estudantes de Medicina da Universidade Estadual de Mato Grosso do Sul
Authors: Magon Amanda , Leite Lucas Rasi Cunha , Cespedes Mateus da Silveira , Souza José Carlos Rosa Pires de
Published: September 2020

Objetivo: Avaliar a empatia e o processo humanístico na relação paciente-estudantes de medicina, sendo estes, acadêmicos do primeiro ao quarto ano do curso de Medicina da Universidade Estadual de Mato Grosso do Sul (UEMS). Métodos: O estudo, realizado de modo quantitativo, observacional e transversal, analisou 84 acadêmicos voluntários de medicina, do 1º ao 4º ano, por meio de questionários aplicados (Escala Jefferson, dados sociodemográficos e Read mind in the eyes). Os dados foram tabulados via Excel 2010 e analisados por meio do teste t-student com 95% de confiabilidade para as três escalas. Resultados: 84 acadêmicos aceitaram participar voluntariamente da pesquisa, preenchendo adequadamente ao TCLE e aos questionários. Dessa amostra, 21,43% pertenciam ao primeiro, 30,95%, ao segundo, 9,52% ao terceiro e 38,1% ao quarto anos. Em relação à Escala Jefferson de Empatia, a média foi de 84,59 pontos para o grupo do 1º ao 2º ano, e de 84,85 pontos para o grupo do 3º ao 4º ano; a média feminina (N = 43) foi de 83,91 pontos e a masculina (N = 41), de 85,56 pontos. No instrumento Read The Mind In The Eyes, a média feminina foi de 26,44 e a masculina, de 25,80. Em relação ao ano de faculdade, a média foi de 26,21 para o 1º e 2º anos, e de 26,05 para o 3º e 4º anos. Conclusão: Foi observado que o grau de empatia entre os acadêmicos do 1º ao 4º ano, bem como entre o sexo feminino e masculino, não foi estatisticamente significante.
Identificando riscos a segurança do paciente idoso com demência: revisão integrativa
Authors: Calvo Doralice das Graças de Melo , Brum Ana Karine Ramos , Messias Claudia Maria
Published: September 2020

Trata se de um estudo de Revisão integrativa com o objetivo de identificar os riscos à segurança do paciente idoso com demência. A pesquisa aconteceu nas bases de dados Medline, Bdenf e Lilacs, abrangendo artigos completos em formato eletrônico, em inglês português e espanhol no período de 2015 a 2020. Após a análise de acordo com os critérios do estudo foram selecionados 29 artigos que constituíram a amostra desta revisão.  Os riscos encontrados foram analisados na perspectiva da segurança do paciente e descritos em oito categorias envolvendo as metas internacionais de segurança do paciente da Organização Mundial de Saúde, os riscos de perdas funcionais relacionadas a deterioração cognitiva, os riscos de perda funcional associadas as  alterações psicológicas e comportamentais das demências e aos riscos à segurança associados a internação. A identificação dos riscos à segurança do idoso com demência é fundamental para a gestão do cuidado seguro.  A progressão do déficit cognitivo predispõe o indivíduo idoso com demência a riscos que podem ser prevenidos ou mitigados através da ótica do cuidado centrado no paciente.
Saúde bucal, qualidade de vida e depressão em idosos independentes: Revisão sistemática
Authors: Moreira de Vasconcelos Ana Karina , Vidal Moreira de Freitas Ana Zuli , Oliveira da Silva Rennis , Alves de Sousa Simone , Laureano Dalle Piagge Carmem Silvia , Cavalcanti Yuri Wanderley
Published: September 2020

Objetivo: Avaliar o impacto da saúde oral na qualidade de vida e depressão de idosos independentes. Método: Revisão sistemática da literatura delineada de acordo com a estratégia PECO com a pergunta: Idosos (População/Controle) que apresentam agravos bucais (Resultados) irão apresentar melhor/pior qualidade de vida e depressão (Exposição)? Resultados: Foram utilizadas as bibliotecas e bases de dados: Medline, Scopus, Web of Science, Lilacs e Cochrane Library, de forma abrangente e irrestrita ao ano ou idioma de publicação. Os MeSH termos usados para pesquisa foram: Elderly; Dental care for aged, Health services for the aged, Depression, Quality of life. Após a busca, 972 artigos foram identificados, dos quais 197 foram excluidos após remoção das duplicatas e 689 por não responderem a pergunta da pesquisa. Após a leitura dos resumos, 6 artigos foram lidos na íntegra e incluídos nessa revisão. Conclusão: As alterações bucais interferem na qualidade de vida e na depressão de idosos independentes.
The Search for World Order and the Wars in Kosovo and Iraq
Authors: Ellison James
Published: September 2020

In the search of world order after the Cold War, two conflicts were of particular significance. The first, in Kosovo in 1999, was fought to end the Serbian genocide of Kosovar Albanians. The second, in Iraq in 2003, was a war of choice ostensibly to remove the threat of Saddam Hussein's Iraqi regime and the weapons of mass destruction it supposedly held. Although distinct, these wars were joined as attempts by the United States governments of Bill Clinton and George W. Bush, either side of the 9/11 attacks, to answer the questions of how, and for what purposes, the US should use its power, and what form of international order it should seek. One foreign leader, the British Prime Minister Tony Blair, sought to influence the Americans in answering these questions. As a result, the Anglo-American relationship was once again important in shaping the course of global affairs. Why and how the wars produced cooperation between two US presidents and Blair, and how ideas about international order featured, are the subjects of this article.
Survei Pengetahuan Orang Tua melalui Kegiatan Sekolah Keluarga Balita (SKB) dengan Online Learning
Authors: Susanti Ari Indra , Ferdian Dani , Annisa Eka Noyan Nur , Calista Raya Faiha
Published: September 2020

Health education in the digital era requires one social media, namely WhatsApp as an information media that is considered effective and efficient. Thus, parents get health education through WhatsApp in the Sekolah Keluarga Balita (SKB) online learning activities with the agreed time. This study aims to determine the knowledge of parents about the First 1000 Days of Life (HPK) through the SKB  online learning that used WhatsApp. The research method used description with a cross-sectional approach. This research was conducted in March 2020 among parents of toddlers living in the fostered villages of Kampung Bestari Astra (KBA) as many as 150 people. The sampling technique was used accidental sampling. This questionnaire was given to the respondent in the form of bit.ly/ (google form). This questionnaire was filled out by respondents before being given a health education video. Data analysis using univariate have presented in the form of a frequency distribution table. The results showed that most participants in the Joint Decree were 135 people, with the age of 20-35 years as many as 60 people, and 78 parents were unfavorable knowledge. The conclusion in this study that some parents aged 20-35 years have less knowledge about the First 1000 Days of Life (HPK) so that health education is needed in a Toddler Family School (SKB) online using WhatsApp.
Quantitative and Qualitative Composition of Bacterial Communities of Malting Barley Grain and Malt during Long-Term Storage
Authors: Felšöciová Soňa , Kowalczewski Przemysław Łukasz , Krajčovič Tomáš , Dráb Štefan , Kačániová Miroslava
Published: September 2020

In the grain samples of three malting barley varieties harvested in 2016, and in the malt made from them, we observed microbial changes during storage. Analyses were performed after 0, 3, 6, and 9 months of storage in floor warehouses and silos. We monitored microbial changes based on the quantitative determination of microorganisms using a plate dilution method and qualitative determination of microorganisms, where we identified a particular species of bacteria using the MALDI-TOF MS Biotyper instrument (Bruker Daltonics, Bremen, Germany). Based on the quantitative determination of microorganisms, we found that the total plate counts of microorganisms was higher in malts than in barley grains. The storage period had the greatest impact on the number of coliform bacteria, which gradually increased with the growing months in storage. The number of lactic acid bacteria in barley grains with the growing months in storage and malt produced from them decreased slightly, and the content of the sporulating bacteria in all the samples fluctuated slightly. Differences in the numbers of observed microorganisms were negligible during storage between floor warehouses and silos. In the samples of barleys, the most commonly identified species were Pantoea agglomerans, which was also present in malt samples but did not belong to the dominant species. A diverse species representation appeared in the samples, whereas predominating species belonged to the Enterobacteriaceae family.
Inflammatory Correlated Response in Two Lines of Rabbit Selected Divergently for Litter Size Environmental Variability
Authors: Beloumi Dhekra , Blasco Agustín , Muelas Raquel , Santacreu María Antonia , García María de la Luz , Argente María-José
Published: September 2020

A divergent selection experiment for environmental variance of litter size variance was carried out in rabbits over thirteen generations. The aim of this study was to evaluate the inflammatory response in the two lines of the experiment, in order to analyse the effect of selection on susceptibility to diseases after challenging to stressful situations, such as 24 h after the first delivery. A total of 78 females were used in this study, 39 from each line. The line selected for litter size heterogeneity (the high line) showed lower white blood leukocyte count (WBC; −0.87 × 103/µL), lower percentage of basophils (−0.11%), higher concentration of TNF-α (+13.8 pg/mL), and greater concentration of CRP (+38.1 µg/mL) than the line selected for litter size homogeneity (the low line). The high line had also higher concentrations of bilirubin, cholesterol, gamma-glutamyl transferase (GGT) and alkaline phosphatase (ALP) compared to the low line (difference between lines were +0.08 µmol/L, +0.14 µmol/L, +0.35 U/L and +2.4 U/L, respectively). The high line showed higher inflammatory response than the low line, in accordance with a larger susceptibility to infectious disorders. In conclusion, the line selected to increase litter size environmental variability seems to have poor capacity coping with environmental stressors. Therefore, selection for litter size environmental variability can be a useful way to improve animal welfare.
Melatonin-Induced Water Stress Tolerance in Plants: Recent Advances
Authors: Moustafa-Farag Mohamed , Mahmoud Ahmed , Arnao Marino B. , Sheteiwy Mohamed S. , Dafea Mohamed , Soltan Mahmoud , Elkelish Amr , Hasanuzzaman Mirza , Ai Shaoying
Published: September 2020

Water stress (drought and waterlogging) is severe abiotic stress to plant growth and development. Melatonin, a bioactive plant hormone, has been widely tested in drought situations in diverse plant species, while few studies on the role of melatonin in waterlogging stress conditions have been published. In the current review, we analyze the biostimulatory functions of melatonin on plants under both drought and waterlogging stresses. Melatonin controls the levels of reactive oxygen and nitrogen species and positively changes the molecular defense to improve plant tolerance against water stress. Moreover, the crosstalk of melatonin and other phytohormones is a key element of plant survival under drought stress, while this relationship needs further investigation under waterlogging stress. In this review, we draw the complete story of water stress on both sides—drought and waterlogging—through discussing the previous critical studies under both conditions. Moreover, we suggest several research directions, especially for waterlogging, which remains a big and vague piece of the melatonin and water stress puzzle.
Dynamic All-Red Signal Control Based on Deep Neural Network Considering Red Light Runner Characteristics
Authors: Kwon Seong Kyung , Jung Hojin , Kim Kyoung-Dae
Published: September 2020

Despite recent advances in technologies for intelligent transportation systems, the safety of intersection traffic is still threatened by traffic signal violation, called the Red Light Runner (RLR). The conventional approach to ensure the intersection safety under the threat of an RLR is to extend the length of the all-red signal when an RLR is detected. Therefore, the selection of all-red signal length is an important factor for intersection safety as well as traffic efficiency. In this paper, for better safety and efficiency of intersection traffic, we propose a framework for dynamic all-red signal control that adjusts the length of all-red signal time according to the driving characteristics of the detected RLR. In this work, we define RLRs into four different classes based on the clustering results using the Dynamic Time Wrapping (DTW) and the Hierarchical Clustering Analysis (HCA). The proposed system uses a Multi-Channel Deep Convolutional Neural Network (MC-DCNN) for online detection of RLR and also classification of RLR class. For dynamic all-red signal control, the proposed system uses a multi-level regression model to estimate the necessary all-red signal extension time more accurately and hence improves the overall intersection traffic safety as well as efficiency.
Opening Size Effects on Airflow Pattern and Airflow Rate of a Naturally Ventilated Dairy Building—A CFD Study
Authors: Saha Chayan Kumer , Yi Qianying , Janke David , Hempel Sabrina , Amon Barbara , Amon Thomas
Published: September 2020

Airflow inside naturally ventilated dairy (NVD) buildings is highly variable and difficult to understand due to the lack of precious measuring techniques with the existing methods. Computational fluid dynamics (CFD) was applied to investigate the effect of different seasonal opening combinations of an NVD building on airflow patterns and airflow rate inside the NVD building as an alternative to full scale and scale model experiments. ANSYS 2019R2 was used for creating model geometry, meshing, and simulation. Eight ventilation opening combinations and 10 different reference air velocities were used for the series of simulation. The data measured in a large boundary layer wind tunnel using a 1:100 scale model of the NVD building was used for CFD model validation. The results show that CFD using standard k-ε turbulence model was capable of simulating airflow in and outside of the NVD building. Airflow patterns were different for different opening scenarios at the same external wind speed, which may affect cow comfort and gaseous emissions. Guiding inlet air by controlling openings may ensure animal comfort and minimize emissions. Non-isothermal and transient simulations of NVD buildings should be carried out for better understanding of airflow patterns.
Vertically Arranged Zinc Oxide Nanorods as Antireflection Layer for Crystalline Silicon Solar Cell: A Simulation Study of Photovoltaic Properties
Authors: Shah Deb Kumar , KC Devendra , Akhtar M. Shaheer , Kim Chong Yeal , Yang O-Bong
Published: September 2020

This paper describes the unique antireflection (AR) layer of vertically arranged ZnO nanorods (NRs) on crystalline silicon (c-Si) solar cells and studies the charge transport and photovoltaic properties by simulation. The vertically arranged ZnO NRs were deposited on ZnO-seeded c-Si wafers by a simple low-temperature solution process. The lengths of the ZnO NRs were optimized by changing the reaction times. Highly dense and vertically arranged ZnO NRs were obtained over the c-Si wafer when the reaction time was 5 h. The deposited ZnO NRs on the c-Si wafers exhibited the lowest reflectance of ~7.5% at 838 nm, having a reasonable average reflectance of ~9.5% in the whole wavelength range (400–1000 nm). Using PC1D software, the charge transport and photovoltaic properties of c-Si solar cells were explored by considering the lengths of the ZnO NRs and the reflectance values. The 1.1 μm length of the ZnO NRs and a minimum average reflectance of 9.5% appeared to be the optimum values for achieving the highest power conversion efficiency of 14.88%. The simulation study for the vertically arranged ZnO NRs AR layers clearly reflects that the low-temperature deposited ZnO NRs on c-Si solar cells could pose a greater prospect in the manufacturing of low-cost c-Si solar cells.
Evolution of a Cognitive Architecture for Social Robots: Integrating Behaviors and Symbolic Knowledge
Authors: Martín Francisco , Rodríguez Lera Francisco J. Rodríguez , Ginés Jonatan , Matellán Vicente
Published: September 2020

This paper presents the evolution of a robotic architecture intended for controlling autonomous social robots. The first instance of this architecture was originally designed according to behavior-based principles. The building blocks of this architecture were behaviors designed as a finite state machine and organized in an ethological inspired way. However, the need of managing explicit symbolic knowledge in human–robot interaction required the integration of planning capabilities into the architecture and a symbolic representation of the environment and the internal state of the robot. A major contribution of this paper is the description of the working memory that integrates these two approaches. This working memory has been implemented as a distributed graph. Another contribution is the use of behavior trees instead of state machine for implementing the behavior-based part of the architecture. This late version of the architecture has been tested in robotic competitions (RoboCup or European Robotics League, among others), whose performance is also discussed in this paper.
Liquid Chromatographic Approach for the Discrimination and Classification of Cava Samples Based on the Phenolic Composition Using Chemometric Methods
Authors: Izquierdo-Llopart Anaïs , Saurina Javier
Published: September 2020

Phenolic profiles obtained by liquid chromatography with UV/vis detection were here exploited to classify cava samples from the protected designation of origin Cava. Wine samples belonging to various classes which differed in grape varieties, blends and fermentation processes were studied based on profiling and fingerprinting approaches. Hence, concentrations of relevant phenolic acids and chromatograms registered at 310 nm were preliminarily examined by Principal Component Analysis (PCA) to extract information on cava classes. It was found that various hydroxybenzoic and hydroxycinnamic acids such as gallic, gentisic, caffeic or caftaric acids were up- or down-expressed depending on the wine varieties. Additionally, Partial Least Squares Discriminant Analysis (PLS-DA) was applied to classify the cava samples according to varietal origins and blends. The classification models were established using well-known wines as the calibration standards. Subsequently, models were applied to assign unknown samples to their corresponding classes. Excellent classification rates were obtained thus proving the potentiality of the proposed approach for characterization and authentication purposes.
Revisiting the Concept of Stress in the Prognosis of Solid Tumors: A Role for Stress Granules Proteins?
Authors: Aulas Anaïs , Finetti Pascal , Lyons Shawn M. , Bertucci François , Birnbaum Daniel , Acquaviva Claire , Mamessier Emilie
Published: September 2020

Cancer treatments are constantly evolving with new approaches to improve patient outcomes. Despite progresses, too many patients remain refractory to treatment due to either the development of resistance to therapeutic drugs and/or metastasis occurrence. Growing evidence suggests that these two barriers are due to transient survival mechanisms that are similar to those observed during stress response. We review the literature and current available open databases to study the potential role of stress response and, most particularly, the involvement of Stress Granules (proteins) in cancer. We propose that Stress Granule proteins may have prognostic value for patients.