bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Analysis of Factors Influencing Informal Investors of Spain and the United States
Authors: Barrachina María de las Mercedes , Baporikar Neeta
Published: October 2022

Informal investors play a significant and critical role in the investment field. Apart from that, informal investors promote entrepreneurship as they are a funding source especially for small and micro entrepreneurs. The objective of this analysis is to identify the factors that characterize the informal investors in Spain and the United States. The basis for this analysis is the data from the website Global Entrepreneurship Monitor (GEM) from the period 2001-2015 at the global individual level for Spain and for United Sates. The purpose is to compare the existing differences between the factors that characterize an informal investor in different economic periods (pre-crisis, crisis, post-crisis) in two different entrepreneurial environments, Spain and United States, to identify measures or actions that can be implemented by the national and local organisms to promote informal investment and entrepreneurship.
An Investigation on the Online Learning Engagement of Malaysian Secondary School Students from Different School Types
Authors: Jaafar Nurjanah Mohd , Ng Lay Shi , Mahmud Najihah , Thang Siew Ming , Mihat Warid
Published: October 2022

This study explored the perceptions of students from different types of schools in Malaysia towards their online learning engagement during COVID-19's movement control order using Fredricks et al.'s framework of behavioural, cognitive, and emotional engagement. In addition to these variables, external support provided to the students was also considered. To this end, a questionnaire that examined the students' general online practices and online learning engagement was administered. Seven hundred sixty-eight students from four different types of secondary schools (national, Chinese, international, and high performing schools) responded to the questionnaire. The findings from the ANOVA analysis indicated that generally the respondents demonstrated positive online learning practices. However, the amount of time spent interacting with teachers online should be much improved. The findings also indicated significant differences in perceptions towards online learning engagement and external support based on school types.
Recognition of Air Passengers' Willingness to Pay for Seat Selection for Imbalanced Data Based on Improved XGBoost
Authors: Hong Baiyu , Ma Xiaolong , Tang Weining , Shen Zhangguo
Published: October 2022

Passenger-paid seat selection is one of the important sources of ancillary revenue for airlines, and machine learning-based willingness-to-pay identification is of great practicality for airlines to accurately tap potential willing passengers. However, affected by periodic statistical errors, air passenger order data often has some problems such as high noise, high latitude, and unbalanced category. In view of this, this paper proposes a method for identifying air passengers' willingness to pay for seat selection based on improved XGBoost, which is improved and integrated from three stages: data, feature, and algorithm. The feasibility of the proposed multi-stage improved integration method is verified by real airline passenger dataset, and the experimental results show that the proposed improved method has better classification effect when compared with the classical six imbalance classification models, which provides a basis for accurate marketing of airline paid seat selection programs.
Assessing the Defence Cooperation Agreements Between the USA and African Countries
Authors: Boateng Paul Coonley , Gyamfi Gerald Dapaah
Published: October 2022

International security cooperation is regarded as one of the key and successful mechanisms to fight terrorism and other cross-border criminal activities worldwide. This paper focuses on the benefits and challenges of the US and African countries' defence cooperation, using Ghana as a case study. This study used 21 people as participants. The subjects were selected based on their unique knowledge and expertise in the phenomenon under study. The researchers used interviews to solicit the views of the participants on the Defence Cooperation Agreement (DCA) between Ghana and the US focusing on the benefits and challenges. In conclusion, the study disclosed that no country has a monopoly on what it takes to fight terrorism and other transnational organised crime alone. The major challenges identified include the breach of domestic law, limited mutual trust, and discriminately ethnic and misguided religious practices. The challenges were stated as indispensable for the sustainability of the DCA and the successful mitigation of terrorism and transnational organised crime in West Africa.
Impact of Normality Pressure on Acceptance of Mobile Phone Technology
Authors: Mushi Renatus Michael
Published: October 2022

The role played by the use of technologies in improving business processes is vital. Taking SMEs, for example, mobile phone technology is used to perform multiple activities, especially in developing countries that are characterized by low ICT readiness. The effective uptake of any technology requires maximum acceptance amongst individuals. While various factors have been studied on how they relate and influence intentions and actual usage of mobile phones amongst employees of SMEs, there is a lack of research that focuses on the social influence in that context. This is a quantitative study performed using SEM involving 459 respondents. The study extends TAM with a subjective norm before testing a resulting theoretical model. The results show that subjective norm has a significant influence on both the perceived usefulness and behaviour intention. This paper also provides recommendations to the key stakeholders on the approaches to utilization of mobile phone technology in SMEs.
Information Management in the Logistics and Distribution Sector Using Metaheuristic Techniques
Authors: Yang Pengbo
Published: October 2022

Information systems (IS) influence logistic and distribution management on sourcing, planning, delivery, and levels ranging from strategic operations to organizational strategy. Information management is a challenging task in logistics and distribution across the business. The supply chain has been increasingly accepted as a significant aid to cut costs and boost services. This paper proposes meta-heuristic techniques (MHT) for effective information management in logistics and distribution, from manufacturers to customers, security, a significant focus on collaboration of operations, co-operation, communication, and knowledge exchange across the supply chain. Modern organizations need advanced decision support systems focused on operative statistical modeling and solution methods and information and communication technology developments to adapt to the integration challenge. It suggests that metaheuristics can play an essential role in addressing complex logistical challenges from logistic architecture and management within the supply chain.
Dynamic Key-Based and Context-Aware Internet of Things Authentication Approach
Authors: Mehta Mihir , Patel Kajal
Published: October 2022

Internet of things can be defined as collection of different physical that can converse with each other without any interruption. The IoT applications have the capability to change the current scenario of various domains such as health service, agriculture, and so on by offering services that can offer luxury to human life and also increases effectiveness. IoT follows open framework. Because of that it presents an opportunity to adversary for easily targeting system by performing various cyber-attacks. Existing well known cryptography solutions cannot be implemented in IoT as it has limitations in terms of resource ownership and also storage capacity. The authors have designed an efficient and secure multi-factor IoT authentication algorithm that is lightweight and provides the protection against different security threats such as MITM, replay, and location spoofing threat. Suggested work is tested on the tool AVISPA for the security validation. Communication and computational cost is low for the suggested work in comparison with the existing work.
Capacity Performance Analysis of 73 GHz Frequency Band for 5G Technology
Authors: Goshe Addis , Routray Sudhir K.
Published: October 2022

Small cells, millimeter waves (mmW), and massive multiple-input multiple-output (MIMO) deployments have emerged as key technologies for mobile systems in the fifth generation (5G). However, a very few studies have been done on combining these three technologies into the cellular systems. In this paper, the authors provide an in-depth capacity analysis for the integrated small cells of mmW systems. Small cells are deployed for enhancing the capacity. It turns out that mmW signals are responsive to blockages, leading the line of sight (LOS) and non-line of sight (NLOS) conditions to have very different path loss rules. They divide power research into low signal-to-noise (SNR) and high SNR regimes based on signal-to-interference plus noise ratio. In the noise-dominated (low-SNR regime), the capacity analysis is derived by the simplest assumptions of the Shannon-Hartley theorem. The results of this study show that under NLOS and LOS scenarios, mmW frequency and distance between the user equipment and base station decrease logarithmically for system capacity.
Fronto temporal dementias
Authors: Caldera Manjula
Published: October 2022

Frontotemporal dementias (FTD) are a heterogenous group of neurocognitive disorders which varies with regard to their clinical presentation, radiological characteristics, pathology and genetics. The core FTD clinical syndromes are behavioural variant FTD (bvFTD), semantic variant primary progressive aphasia (svPPA) and non-fluent/ agrammatic variant of primary progressive aphasia (nfvPPA). FTD related syndromes include frontotemporal dementia with motor neuron disease (FTD-MND), progressive supranuclear palsy syndrome (PSP-S) and corticobasal syndrome (CBS). This article discusses the clinical presentation, diagnosis, neuropathology, neurogenetics and therapeutics of FTDs.
Persistent hiccups as a rare presentation of Ramsey Hunt syndrome in a renal transplant recipient
Authors: Hettige D.H. , Weerawansa M.R.P. , Senanayake H.M.S. , Sumathipala S. , Rupasinghe R.T. , Caldera M.C.
Published: October 2022

Ramsay Hunt syndrome type 2, also known as RHS and herpes zoster oticus, is a disorder that is caused by the reactivation of varicella zoster virus in the geniculate ganglion, a nerve cell bundle of the facial nerve. RHS typically presents with inability to move many facial muscles, pain in the ear, taste loss on the front of the tongue, dry eyes and mouth, and a vesicular rash. However, the association of RHS with multiple cranial nerve involvement and persistent hiccups is less well reported.
Pronounced isolated severe apraxia of speech, a rare presentation of an acute ischaemic stroke
Authors: Caldera Manjula C. , Welagedara Rakhitha L. , Dayaratne K.G. , Weerasinghe S.C.
Published: October 2022

A 39-year-old previously healthy woman presented with sudden onset loss of speech. Except for subtle right facial asymmetry, no other neurological deficits were found. A non-contrast CT scan was unremarkable. She was thrombolised with iv alteplase (0.9mg/kg standard dose) after 2 hours from the onset.
Baby Crying Analyzing and Solution using MATLAB Graphical User Interface; Interdisciplinary Collaboration between Engineering and Nursing
Authors: Yilmaz Efe Çetin , Ozdemir Serap
Published: October 2022

Background:

Babies can express all their needs (such as hunger, pain, tiredness, discomfort, and so on) to their parents with crying behavior that being able to predict these behaviors of babies correctly parents is extremely important for the comfort of babies. In recent years, analyzing the baby crying sound and interpreting it in line with the needs has been developing as an important process in the estimation of baby needs.

Methods:

Analyzing the spectra of the baby crying sound over time and amplitude period creates a significant knowledge base on the prediction of baby needs. Within the scope of this study, a new method has been developed for the development of various technical analyzes of a sample baby crying sound using the MATLAB program.

Results:

With this method, the energy fluctuations in the sample baby crying sound were analyzed, and the changes in the crying process were examined through the baby crying process.

Conclusions:

As a result, thanks to the analysis data obtained within the scope of this study, it is aimed to provide data to autonomous controlled baby care units that can be manufactured in future studies.
Risk Factors for Abscess Development in Patients with Endometrioma Who Present with an Acute Abdomen
Authors: Kaseki Hanako , Ichikawa Masao , Toyoshima Masafumi , Matsuda Shigeru , Nakao Kimihiko , Watanabe Kenichiro , Ono Shuichi , Takeshita Toshiyuki , Akira Shigeo , Suzuki Shunji
Published: October 2022

Objectives:

The objective of this study was to assess the potential risk factors for abscess development in patients with endometrioma who present with an acute abdomen.

Materials and Methods:

We retrospectively reviewed the records of 51 patients who underwent emergency surgery for acute abdomen involving an endometrioma at our hospital between April 2011 and August 2021. The patients were divided into an infected group (n = 22) and a control group (n = 29). We analyzed patient characteristics; imaging findings; clinical data, including bacterial cultures; and perioperative outcomes to assess for differences between groups.

Results:

Patients in the infected group were significantly older than those in the control group (P = 0.03). They were more likely to have a history of endometriosis surgery (P = 0.04) and more likely to have undergone transvaginal manipulation within 3 months of presentation (P = 0.01). Body temperature on the day of admission was significantly higher in the infected group (P = 0.007), as were C-reactive protein levels on the day of admission and before surgery (P < 0.001; P = 0.018) and the white blood cell count on the day of admission (P = 0.016). Preoperative imaging showed significant thickening of the tumor wall (P < 0.001) and an enhanced contrast effect (P < 0.001) in the infected group.

Conclusion:

We identified several factors that suggest abscess in patients with an acute abdomen who have a complication of pathologically confirmed endometriosis. A recent vaginal procedure is a particular risk factor for abscess development in patients with endometriomas.
Ovarian Ligament Plication as a Treatment for Patient with Elongated Ovarian Ligament with Recurrent Abdominal Pain in the Absence of Ovarian Torsion
Authors: Rai Rakhi , Roy Kallol Kumar , Zangmo Rinchen , Nair Vinod , Jain Aayush
Published: October 2022

Elongated ovarian ligament can lead to adnexal torsion. Several cases of ovarian torsion have been reported where the ovarian ligament was elongated, and ovarian detorsion and ovarian ligament plication were done. In our case, a young girl presented with recurrent left lower abdominal pain, especially after exercise, with normal ovaries found on ultrasound. Laparoscopy was performed given recurrent pelvic pain and found elongated left ovarian ligament with normal ovaries. Considering the possibility of recurrent torsion and detorsion of the ovary due to elongated left ovarian ligament, left ovarian ligament plication was done. The patient remained pain-free till 1 year of follow-up. No such case has been reported in the literature where the ovarian ligament plication was performed without torsion. Hence, elongated ovarian ligament could cause recurrent pelvic pain due to possible torsion, and a simple, easy procedure of ovarian ligament plication can help relieve pain.
Zero Phaco: A new technique for dealing with soft cataracts
Authors: Bardoloi Narayan , Sarkar Sandip , Dholkawala Roshni
Published: October 2022

Phacoemulsification in soft cataracts can be challenging due to the lack of rigid cleavage planes and the inability to crack. We describe a new phacoemulsification technique for dealing with soft cataracts using high vacuum and zero energy. Following capsulorhexis and hydrodissection, we introduced the phacoemulsification probe, keeping the torsional and longitudinal power at zero. A central groove was created in sculpting mode. We held the nucleus with adequate vacuum in chop mode and divided the nucleus. Then, we rotated and chopped the nucleus similarly into small pieces without using any power. For emulsification, we increased the vacuum to 600 mmHg and then shredded and stuffed the pieces into the phaco probe by the chopper. A newer generation phaco machine with active fluidic system and monitored pressurized infusion helps the surgeon control the intraocular pressure (IOP) and hold the nucleus with vacuum alone, allowing chopping and emulsifying of the pieces without any energy.
Single-arm tool for assessment of anomalous head posture
Authors: Fathima Allapitchai , Meenakshi Ravindran
Published: October 2022

Background:

Anomalous head posture (AHP) measurement is crucial in the management of nystagmus and incomitant strabismus and also during follow-up assessments. The types of AHP include chin posture, head tilt, and face turn. Goniometer is a low-cost tool widely used to measure head posture. This has two arms: one reference arm and one measuring arm. The drawback of this device is that the examiner has to maintain the reference arm exactly parallel or perpendicular to the floor and the other arm has to align the AHP. Since not all the examiners are comfortable in aligning both the arms simultaneously, the measurements obtained by a goniometer end up being less accurate. A device named cervical range of motion (CROM) is more reliable but expensive. There is an iOS application created for the purpose of head posture assessment, but an iPhone is expensive.

Purpose:

To demonstrate a low-cost, innovative, reliable single-arm tool (SAT) for assessment of AHP.

Synopsis:

A clinometer is a device that is used to measure the heights of buildings. In this device, the gravitational force of the earth determines the reference line. We have modified a clinometer into a SAT by incorporating a long plastic arm to it, which is used to measure head tilt and chin up/down measurements. For the purpose of face-turn measurement, we modified a compass for direction into another type of SAT by fitting a yoke dial and a long plastic arm to measure face turn. Here, the principle is to have the line of direction as a reference. The direction of the patient’s seating arrangement is determined and taken as the reference direction. The amount of the patient’s face turn is measured by finding out the angle between reference direction and direction of the nose.

Highlights:

This video shows the method of making SAT in a do-it-yourself manner and also demonstrates the method of measuring AHP. SAT is a reliable and low-cost device.

Online Video Link:

https://youtu.be/UwoHARok85c
COVID-19 provoked internuclear ophthalmoplegia in a child with arrested hydrocephalus
Authors: Fathy Mohamed , Alrashidi Salah , Hagras Sherein M
Published: October 2022

Internuclear ophthalmoplegia (INO) is a neuro-ophthalmic disorder caused by damage in the medial longitudinal fasciculus between the third and sixth cranial nerve nuclei. We present a 4-year-old female diagnosed with INO triggered by coronavirus disease 2019 (COVID-19) infection. The patient had history of neonatal meningitis with hydrocephalus without history of surgical intervention. To the best of our knowledge, this is the first case with combined COVID-19 and chronic hydrocephalus as an etiology for INO in a child. COVID-19 may trigger neurological manifestations as INO in susceptible cases.
A novel biodegradable polymer scaffold for in vitro growth of corneal epithelial cells
Authors: Bhardwaj Kanika , Sridhar Uma
Published: October 2022

The shortage of donor corneal tissue worldwide has led to extensive research for alternate corneal equivalents utilizing tissue engineering methods. We conducted experiments using Poly D, L lactic acid polymer along with a copolymer (Eudragit) in varying concentrations to create a biodegradable scaffold suitable for in vitro growth of corneal epithelial stem cells. It was found that stable, spherical, and porous microparticles can be prepared by combining PDLLA and Eudragit RL100 polymers in the ratio of 90:10 and 70:30. The microparticles can then be fused to form scaffold membranes with porous architecture and good water retention capacity at room temperature using methanol, which can withstand handling during transplantation procedures. The scaffolds made using a 70:30 ratio were found to be suitable for the promotion of growth of laboratory corneal epithelial stem cell lines (SIRC cell lines). This innovation can pave way for further developments in corneal stem cell research and growth, thus providing for viable laboratory-derived corneal substitutes.
Femtosecond laser deep lamellar keratoplasty
Authors: Farid Marjan , Rostov Audrey Talley
Published: October 2022

We aimed to develop a novel and effective technique for creating a smooth deep lamellar dissection of the cornea using a femtosecond (FS) laser for deep anterior lamellar keratoplasty (DALK), we conducted a retrospective eye bank study. Thirteen fresh human corneas were mounted on an artificial anterior chamber, and deep lamellar cuts were made with a 500-kHz VisuMax FS laser at a level of 50–80 mm anterior to the Descemet’s membrane (DM). A posterior diameter of 8 mm with a side cut angle of 110° was used for the anterior penetrating side cut. The anterior lamellar tissue was bluntly dissected. The residual posterior stromal beds and side cuts were examined with microscopy and intraoperative optical coherence tomography (OCT) and post-cut endothelial cell evaluations. All corneas revealed a smooth residual posterior stromal bed without any visible irregularities or ridges by microscopy and OCT imaging. Six corneas were suitable for post-cut endothelial cell evaluation 2 days after laser cut, with no significant endothelial cell loss post-laser and blunt dissection of the posterior stroma. FS laser deep lamellar keratoplasty utilizing an ultrafast laser to produce a smooth deep stromal dissection followed by blunt dissection and removal of the anterior stromal tissue yields a consistent and smooth residual stromal bed. The creation of a smooth lamellar dissection in the deep posterior cornea may result in more consistent DALK without the need for air bubble or manual baring of DM that has the risk for DM perforation.
Comparison of three techniques of harvesting full-thickness retinal tissue for large or persistent macular holes
Authors: Dhami Abhinav , Biswas Rupak Kanti , Dogra Mohit , Singh Ramandeep , Mittal Sangeet , Ratra Dhanashree
Published: October 2022

Purpose

To evaluate the success rate of autologous retinal graft (ARG) for the closure of full-thickness macular holes (MHs) and compare the outcomes of three different techniques of harvesting the graft.

Methods

Clinic files of all patients who had undergone ARG for MH using intraocular scissors, membrane loop, or retinal punch to harvest retinal tissue were retrospectively reviewed. All patients were evaluated for MH closure, retinal reattachment, and visual improvement.

Results

Twenty-two eyes of 22 patients were included. ARG was done for 16 eyes (72.7%) with failed, large persistent MH, and six eyes (27.3%) also underwent simultaneous repair of retinal detachment. The basal diameter of MH was 1103.67 ± 310.09 (range 650–1529) mm. Intraocular scissors were used in 10 eyes (45.5%), a membrane loop in five eyes (22.7%), and a retinal punch in seven eyes (31.8%). Silicone oil tamponade was used in seven (31.8%) eyes and gas in 15 (68.1%) eyes. The follow-up ranged from 6 to 18 months. The hole closure rate was 72.7% (16/22). Visual improvement was noted in 18 eyes (81.8%). Retinal reattachment was seen in all eyes. Good graft integration with the surrounding area was seen in 17 eyes (77.3%). Graft retraction was seen in four eyes (18.18%) and graft loss in one eye (4.55%). No significant differences were noted among the three groups.

Conclusion

ARG is successful in closing large, failed MH with and without retinal detachment. A membrane loop and retinal punch are equally useful in harvesting the graft, but scissors are preferable in case the retina is detached. With all three techniques, integration of the graft with the surrounding tissue can be achieved.
Clinical differentiation of Pythium keratitis from fungal keratitis and development of a scoring system
Authors: Chatterjee Samrat , Agrawal Deepshikha , Gomase Sharad Nivrutti
Published: October 2022

Purpose:

To differentiate Pythium keratitis from fungal keratitis using clinical signs, to explore usefulness of various signs as diagnostic prognosticators, and develop a clinical scoring system.

Methods:

A retrospective review of medical records and archived clinical photographs of patients with culture-positive Pythium keratitis and hyaline filamentous fungal keratitis was conducted at a tertiary eye institute to explore characteristics of ulcers that may aid diagnosis.

Results:

Full-thickness corneal stromal keratitis (P = 0.055), a dry ulcer surface (P = 0.010), tentacles (P < 0.0001), intrastromal dots (P < 0.0001), ring infiltrates (P = 0.024), reticular patterns (P < 0.0001), and peripheral furrows (P < 0.0001) were clinical signs associated with Pythium keratitis. Multiple regression analysis identified tentacles (odds ratio: 24.1, 95% confidence interval (CI): 3.8–158.1, P = 0.001) and peripheral furrows (odds ratio: 60.6, 95% CI: 5.1–712.3, P = 0.001) as independent diagnostic prognosticators for Pythium keratitis. The positive and negative likelihood ratios of a dry ulcer surface, tentacles, intrastromal dots, ring infiltrates, reticular patterns, and peripheral furrows predicting Pythium keratitis were 1.6, 13.6, 17.9, 4.3, 30.7, 15.3 and 0.4, 0.4, 0.7, 0.9, 0.6 and 0.8, respectively. The presence of two or more of these clinical signs (excluding a dry ulcer surface) had a sensitivity of 55.6% and a false positive rate of 1.4%.

Conclusion:

Tentacles, intrastromal dots, ring infiltrates, reticular patterns, and peripheral furrows are clinical signs to be considered for the diagnosis of Pythium keratitis and the presence of two or more signs has a very low false positive rate.
Serum 25-hydroxyvitamin D levels and the risk of non-alcoholic fatty liver
Authors: Sheng Qi , Shi Huanchen , Liu Shousheng , Zhuang Likun , Zhao Zhenzhen , Xin Yongning
Published: October 2022

Background:

Accumulated studies have shown that low expression of 25-hydroxyvitamin D [25(OH)D] was significantly associated with the risk of non-alcoholic fatty liver disease (NAFLD). However, the exact causality is still unknown. The aim of this study was to investigate whether levels of 25(OH)D are associated with risk of NAFLD, using a two-sample Mendelian randomization (MR).

Methods:

Data from a recent large vitamin D genome-wide association study (GWAS) on 417,580 Europeans were utilized, and the largest published histology-based NAFLD GWAS study (1,483 cases and 17,781 healthy controls) for genetic variants predicted to cause NAFLD were searched. All genetic datasets for the MR analyses were obtained using publicly available summary statistics based on individuals of European ancestry from the MR-Base and NHGRI-EBI GWAS Catalog database. Inverse-variance weighted (IVW) MR approach was used to estimate causal effects in the main analysis, complemented by 4 additional methods to control for pleiotropy. Sensitivity analyses were conducted to verify whether heterogeneity and pleiotropy can bias the MR results.

Results:

The MR analysis did not provide strong evidence for the causal association of circulating 25(OH)D with NAFLD by IVW method (OR = 0.746, 95%CI 0.517–1.078; P = 0.119). The results were consistent using four other MR methods. Sensitivity analysis using all different analytical approaches yielded similar results. There was no evidence for pleiotropy (MR-Egger intercept: −0.0003758, P = 0.970). The replication process also showed consistent results using IVW method (P = 0.710).

Conclusion:

This study indicates that serum 25(OH)D levels did not possess an obvious effect on the risk of NAFLD. The associations in previous studies may be due to residual confounding or reverse causation.
Anomaly detection of smart metering system for power management with battery storage system/electric vehicle
Authors: Lee Sangkeum , Nengroo Sarvar Hussain , Jin Hojun , Doh Yoonmee , Lee Chungho , Heo Taewook , Har Dongsoo
Published: October 2022

A novel smart metering technique capable of anomaly detection was proposed for real‐time home power management system. Smart meter data generated in real‐time were obtained from 900 households of single apartments. To detect outliers and missing values in smart meter data, a deep learning model, the autoencoder, consisting of a graph convolutional network and bidirectional long short‐term memory network, was applied to the smart metering technique. Power management based on the smart metering technique was executed by multi‐objective optimization in the presence of a battery storage system and an electric vehicle. The results of the power management employing the proposed smart metering technique indicate a reduction in electricity cost and amount of power supplied by the grid compared to the results of power management without anomaly detection.
Fabrication and Characterization of Bimetal Sulfide Hybrid Ag/S-ZVI for Dechlorination of Trichloroethylene
Authors: Zhang Shubin , Wang Tianxiao , Guo Xin , Chen Shengwen , Wang Lijun
Published: October 2022

Sulfidated and bimetal modification can improve the reactivity and selectivity of zero-valent iron in contaminant removal. However, previous studies were focused on unilateral material approaches. In this article, a new hybrid composite Ag/S-ZVI was prepared by doping elemental silver on surface of sulfidated nanoscale zerovalent iron (S-nZVI). The results of X-Ray Diffraction (XRD), energy dispersive spectrometer (EDS) and X-ray Photoelectron Spectroscopy (XPS) indicated Ag was dispersed on the surface of S-nZVI. Scanning electron microscope (SEM) images displayed Ag/S-ZVI was irregular clusters with rough surfaces, small agglomeration, and quasi-spherical in shape. The removal of TCE by Ag/S-ZVI was 90.4% within 20 min. The reaction rate constant Kobs of Ag/S-ZVI was 2.59 times or 1.85 times of nZVI or S-nZVI, respectively. Cycling experiments showed that Ag/S-ZVI had good recycling ability, and the removal rate of TCE reached 72.6% at the third cycle. The addition of Ag+ makes S-nZVI as an abundant and efficient source of reducing electrons. The Fe0 core can break C-Cl bonds by releasing electrons and the surface layer of Ag favors the transfer efficiency of electrons. Such study provides an efficient and robust ternary system for the remediation of TCE in groundwater.
High-class apartment selection factors in Ho Chi Minh City
Authors: Phong Nguyen Thanh , Thu Nguyen Anh , An Le Thi Thuy
Published: October 2022

This paper aims to find out the current state of the high-class apartment market. Qualitative research is done to adjust and supplement the observed variables for the scale. Quantitative research is conducted through a survey of customers who have bought a high-class apartment or are intending to buy an apartment to build a research model and test the scale. After collecting data, the study conducted the descriptive statistical analysis, testing the reliability of scale. Then, the Exploratory Factor Analysis (EFA) was performed to group the related factors into groups of factors that are independent. The research results showed that there are eight main groups of factors with 31 related observational variables that affected customers' decisions to choose high-class apartments.
Effect of cucurbiturils on cytokine production by peripheral blood mononuclear cells of healthy donors
Authors: Aktanova A. A. , Kovalenko E. A. , Pashkina E. A.
Published: October 2022

Many drug delivery systems are currently under study, e.g., nanosized cavitands cucurbiturils, which, due to the presence of a cavity, can incorporate drug molecules. Since the immune system is quite sensitive to influence of nanomaterials and other cell-damaging factors, it is necessary to study immunosafety of the new delivery systems, i.e., immunotoxicity and immunomodulatory properties. The aim of this study was to investigate the effect of nanosized cucurbituril cavitands on the cytokine-producing ability of peripheral blood mononuclear cells in apparently healthy donors.

Blood mononuclear cells (106/mL) were cultured in the presence of cucurbiturils at the following concentrations: 0.3 mM cucurbit[6]uril, 0.3 mM cucurbit[7]uril, and 0.01 mM cucurbit[8]uril for 72 h, under additional stimulation with aCD3 antibodies (1 g/mL), or without it. The level of cytokines in the supernatants was determined using enzyme immunoassay.

It was shown that cucurbit[6]uril increased the level of spontaneous IL-4 production by 1.5 times (p 0.01) compared with the control. In the case of stimulated cytokine production, we found that cucurbit[6]uril reduced the level of IL-6, and also shows a tendency (p = 0.09) towards an increase in the IL-4 level. When cells were cultured with cucurbit[7]uril, we gave revealed a trend for increased production of pro-inflammatory TNF. It was also found that cucurbit[7]uril is able to suppress the production of IL-10 in aCD3-stimulated cell culture by 1.5 times. Cucurbit[8]uril was shown to inhibit production of cytokines in non-stimulated cell cultures. A significant decrease in the level of IFN and IL-10 was revealed as compared with the production of these cytokines in control cultures. When assessing the effect of cucurbit[8]uril on the IFN production upon stimulation with aCD3 antibodies, no significant differences were found, but there is also a trend for a decreased concentration of this cytokine agains control levels.

Cucurbiturils can influence both spontaneous and stimulated production of cytokines by the blood mononuclear cells. The effect on cytokine-producing ability of the cells depends on the tested homologue compound.
MicroRNA signature of leukocytes in the context of chronic systemic inflammation in vascular dementia
Authors: Burmistrova A. L. , Alekseeva A. S. , Cazaux M. E. , Filippova Yu. Yu.
Published: October 2022

Chronic low-level inflammation during the aging process is a key risk factor for the activation of resident cells of the brain innate immune system of the (microglia and astrocytes). Such activation leads to the development of neuroinflammation and cognitive impairment which are typical to neurodegenerative diseases such as Alzheimers disease, vascular dementia, Parkinson disease etc. Currently, there is a lack of minimally invasive, affordable methods for diagnosing age-related neurodegenerative diseases and drugs that could slow down or prevent their progression. Hence, a search for new peripheral biomarkers is required, both for diagnostics and monitoring the efficiency of drug therapy. The option of using microRNAs as such biomarkers is under discussion. Our goal was to identify a leukocyte microRNA signature in vascular dementia as compared with healthy aging and reproductive age, in view of inflammation and cognitive deficits. We have examined 54 persons from young to senile age who were classified into the following groups: Vascular dementia, Healthy aging and Reproductive age. Expression of miRNAs known as regulators of communications between the immune and nervous systems (let-7d, let-7g, miR-21, miR-124, miR-146a, miR-155, miR-342-3p) was measured in peripheral blood leukocytes. The decision to study leukocytes was made, since these blood cells are responsible for immune functions, and, especially, cytokine production during aging. Total RNA was isolated by phenol-chloroform technique. The microRNA expression was determined by quantitative polymerase chain reaction with SYBRGreen. The U6 gene of small nuclear DNA was used as a reference housekeeping gene. The differences between groups were determined using the KruskalWallis test with post hoc pairwise comparisons according to ConoverInman. As a result of the study, it was found that the expression of microRNA-21 and microRNA-342 in leukocytes of elderly/senile people, both in healthy aging and in vascular dementia, was increased when compared to the persons in their reproductive age. In the persons with vascular dementia, the expression level of miRNA-124 and miRNA-342 in peripheral blood leukocytes was higher than in healthy aging group. Hence,, microRNA-124 and microRNA-342 may be informative biomarkers for the diagnostics of vascular dementia. However, large-scale studies of their biomarker potential are warranted.
Marketing: comunicación digital, fidelización y política pre y post COVID-19
Authors: Flores Fernández Mileydi , Llanos Díaz Elmer , Pajares Chilcho Eva Mariceli , Llanos Flores Marcel Junior , Ayala Díaz David Antonio , Díaz Santoyo Leo , Duarez Aguilar Alan Fabricio , Rodríguez Alarcon Sebastian , Carrasco Vilcherrez Eduardo Antonio , Córdova Chorres Kelly Jamiletth , Damián Anton Gabriela Luiseld , Wong Aitken Higinio Guillermo
Published: October 2022

Marketing: comunicación digital, fidelización y política pre y post COVID-19 recoge la investigación de la problemática ocasionada en escenarios de aguda crisis provocada por la Pandemia COVID-19 en la gestión empresarial y en la dinámica política. Se encuentra dividió en tres capítulos, en Capítulo I: Encontramos un artículo sobre el impacto que las redes sociales ejerce en el escenario político y la construcción de la ciudadanía democrática basado en la construcción del imaginario respondiendo a la pregunta ¿En verdad peligra la democracia en las redes sociales? Revisamos la pertinencia de las políticas democráticas en escenarios de pandemia. Ponemos a su disposición las investigaciones: Estrategias de comunicación digital para incrementar la cartera de clientes donde usted encuentra información que busca explicar la influencia de la aplicación de las estrategias comunicativas del marketing y su influencia en la ampliación de cartera de clientes, así mismo; busca analizar la relación existente en las estrategias de comunicación aplicadas en el Marketing digital para la fidelización de clientes, también hacemos un abordaje de la comunicación digital y el impacto en la construcción de la democracia, una mirada desde la política. Así mismo ponemos a disposición la relación existente entre el Marketing Digital Para La Fidelización De Clientes En Escenarios De COVID-19; este importante aporte que utiliza la metodología de investigación científica. En ambos casos un estudio de antecedentes de investigación, metodología, recojo y procesamiento de información, conclusiones y recomendaciones.
Investigaciones sobre mercados gastronómicos en escenarios de pandemia
Authors: Flores Fernández Mileydi , Carrasco Chávez Marco Antonio , Pinedo Lozano Cesar Eduardo , Becerra Zuloeta Vanesa , Larios Farro Elizabeth Rebeca , Loconi Sánchez Lesslie Vasti , Núñez Julón Maria Lesly , Radahelly Morales Yampierr , Rivera Córdova Arlet Yenifer , Vera Córdova Tatiana Lorena , Wong Aitken Higinio Guillermo
Published: October 2022

En este libro encuentra información referida a los estados de los centros de atención gastronómica llámese restaurantes turísticos, marisquería, picantería y su desenvolvimiento en época de pandemia COVID-19, sus posibilidades de desarrollo a partir de los ajustes hechos para generar satisfacción de los clientes en escenarios de nueva normalidad. En el primer estudio de caso recogemos el análisis de la calidad del servicio antes y del COVID-19 y la correspondiente satisfacción de los usuarios lo que conlleva a generar propuestas de mejoramiento de servicios gastronómicos. El segundo estudio, hace una propuesta de marketing digital con la finalidad de mejorar el posicionamiento de un restaurante turístico en escenarios de pandemia COVID-19, haciendo uso de herramientas libres de internet y verificando su efectividad. Ambas investigaciones tuvieron como propósito mejorar la calidad de servicio y desarrollo de estrategias de marketing digital para mejorar la percepción de los clientes y el posicionamiento de la organización.
SUBJETIVIDADE JURÍDICA INTERNACIONAL NA DOUTRINA BRASILEIRA DO SEGUNDO IMPÉRIO: “NAÇÃO” E “ESTADO” NA CIÊNCIA DO DIREITO INTERNACIONAL
Authors: Bedin Guilherme , Dal Ri Jr. Arno
Published: October 2022

O presente artigo estuda a definição dos termos Nação e Estado utilizadas pelos juristas ao longo do período do Brasil Império e avalia como cada um deles se relaciona com o conceito de subjetividade jurídica internacional. Para tanto, foram analisados os principais compêndios utilizados na segunda metade do século XIX nos cursos jurídicos brasileiros, no tocante ao ensino do direito internacional. O problema abordado neste artigo não se limita a reunir as aparições dos termos “Nação” e “Estado” enquanto simples vocábulos, mas sim se aprofundar no sentido que a eles é atribuído por cada autor no período e, deste modo, verificar a correlação deste com a temática da subjetividade jurídica internacional. Percebe-se que os autores brasileiros mesmo que se ocupem de definir os termos, não atribuem a eles especial relevância jurídica, com exceção de Carlos Vidal de Oliveira Freitas, que defende o Estado como sujeito de direito internacional.
Gestión tutorial y liderazgo personal en tiempos de COVID-19 para estudiantes de educación universitaria
Authors: Montañez Huancaya de Salinas Aquila Priscila , Hilares Soria María Salomé , Roca Avila Yovana Connie , Figueroa Hurtado Fany Silvana , Arainga Blas Eusebio , Holguín Álvarez Jhon , Triviños Chalco Angel Julber
Published: October 2022

La gestión de tutoría universitaria, cada vez se hace más importante durante la formación profesional de los estudiantes y esto hace que sea necesario la implementación de un programa tutorial sostenible. Con esta idea se ha formulado el siguiente objetivo: determinar cómo influye la gestión de tutoría para el liderazgo personal y propósito de vida en tiempos de COVID 19 de estudiantes de Educación Universitaria. La investigación por su naturaleza corresponde al enfoque de investigación cuantitativa, de diseño con pre prueba-post prueba, grupos experimentales y grupos de control; se ha experimentado el programa tutorial; para observar el comportamiento de la variable dependiente se ha aplicado la Escala de Apreciación Descriptiva-EAD de chequeo, validados a través de juicio de expertos (93 %) y con coeficiente confiabilidad de Alfa de Cronbach. Como resultado se evidencia que en el pre test de los examinados que forman parte del grupo experimental se obtuvo el promedio de 56,47 y el promedio del pre test del grupo control es 40,99, en la post prueba el grupo experimental obtuvo un promedio de 79,62 considerado aprobatorio alto y en el grupo control su promedio fue 54,82; se demuestra que la gestión de tutoría influye positivamente para el liderazgo personal y propósito de vida en tiempos de COVID 19 de estudiantes de educación universitaria.
Herramientas sincrónicas, asincrónicas y desempeño docente en tiempo de pandemia
Authors: Robles Orué Jorge Germán , Jiménez López Eusebia Soledad , Astete Barrenechea Carlos Alberto , Marroquín Peña Roberto , Cavero Ramírez Francisca
Published: October 2022

Desde la aparición de la pandemia a causa del Covid 19, el sector educación tuvo migrar al uso de herramientas tecnológicas para llevar a cabo el proceso de enseñanza. El objetivo principal de la investigación fue determinar la incidencia de las herramientas sincrónicas y asincrónicas en el desempeño docente en tiempo de pandemia COVID 19. La investigación fue de enfoque cuantitativo, de tipo básica sustantiva, de diseño no experimental, correlacional, multivariable contó con la participación de 27 docentes, a quienes se les evaluó mediante tres instrumentos construidos en base a las tres variables, dimensiones e indicadores correspondientes. Existe incidencia significativa de las herramientas sincrónicas y asincrónicas en el desempeño docente en tiempo de pandemia COVID 19 de la Facultad de Pedagogía y Cultura Física de la UNE-EGyV, 2021. (F = 7,819 y p-value (sig.) igual a cero, es menor de ? = 0,05 (5%), asimismo según la correlación de r de Pearson = 0,628 (X1*Y) positiva alta y r de Pearson = 0,613 (X2*Y) positiva alta.
Las variables extralingüísticas en el uso del eufemismo y disfemismo en los universitarios limeños
Authors: Barrios Tinoco Luis Magno , Huayre Ignacio Emiliano Zolano , Polack Peña Ana María , Ramírez Ríos Alejandro , Campos Manrique Haendel , Saldaña Sánchez Eva Luz
Published: October 2022

La perspectiva sociolingüística brinda un panorama del por qué los universitarios hacen uso de los eufemismos y disfemismos durante su desenvolvimiento en la vida diaria. El objetivo de la investigación consistió en determinar la diferencia entre el uso de los eufemismos y disfemismos según las variables extralingüísticas en los universitarios limeños. Para el desarrollo de la investigación se aplicó el método cuantitativo de diseño no experimental, transversal, la muestra de tipo no probabilística se constituyó de un total de 52 universitarios. Se aplicó la técnica de la encuesta y como instrumento el cuestionario, que obtuvo una confiabilidad de Alfa de Cronbach superior a 0,7. Los resultados descriptivos indicaron la existencia de diferencias en el uso del eufemismo y disfemismo en los estudiantes universitarios tanto en género, edad y lugar de procedencia. Coinciden con los resultados de la investigación los investigadores internacionales (Morales, 2021; Fernández, 2014; Ríos, 2011) y los peruanos (Quesada et al., 2000; Giraldo, 2014). La prueba de hipótesis con el   estadístico de Wilcoxon para muestras relacionadas dio como resultado un p-valúe inferior a 0,05, se concluye que existe diferencia entre el uso del eufemismo y disfemismo según las variables extralingüísticas en los universitarios limeños.
Marcas orales en trabajos de investigación para la obtención del título profesional en una universidad pública
Authors: Idrogo Barboza Gloria , Huaman Guzman Abraham Moises
Published: October 2022

La escritura de textos académicos es una actividad compleja que requiere del dominio lingüístico y normativo; la oralidad, en cambio, como acción primaria prescinde de algunos recursos formales porque se complementa con otros elementos para su entendimiento. Cuando la oralidad se inserta en la escritura rigurosa de carácter científico, se evidencian las marcas orales como un problema en la redacción, punto de partida para la investigación que como objetivo se planteó describir la persistencia de las marcas orales en las tesis de posgrado. La metodología que se aplicó es de enfoque cualitativo, de diseño, teoría fundamentada. La recopilación de información se realizó a través de fuentes documentales con licencia liberada. El análisis de datos se realizó con el programa de Atlas.ti, este permitió registrar 94 códigos agrupados en dos categorías: nivel léxico semántico y morfosintáctico. Los resultados se discutieron con los antecedentes de la investigación de soporte teórico. Finalmente, se concluye que la persistencia de las marcas orales en la escritura de tesis con gran predominio el de repeticiones léxicas en la sección de la introducción, permitirá proponer alternativas en el desarrollo de la escritura del texto académico y mejorar el filtro por el cual deben seguir antes de ser publicados y difundidos.