bluuebunny/crossref_metadata_2025 huggingface dataset:
Pemetaan Jangkauan Fasilitas Kesehatan di Provinsi Daerah Istimewa Yogyakarta (DIY) Menggunakan Software QGIS
Authors: Saputra Rizki Kurniawan , Purnama Aditya Yoga , Perdhana Radhitya
Published: November 2023

Tujuan utama dari penelitian ini adalah untuk menganalisis pola spasial jangkauan pelayanan kesehatan di Kota Yogyakarta menggunakan software QGIS. Software QGIS dipilih karena memiliki kelebihan yaitu open source dan user friendly. Metode yang digunakan yaitu analisis spasial menggunakan buffer dan overlay. Data yang digunakan diantaranya data administrasi wilayah, fasilitas kesehatan, dan jalan. Jenis data yang digunakan berupa data sekunder yang didapatkan dari website resmi https://tanahair.indonesia.go.id/portal-web. Dalam penelitian ini dibatasi pada wilayah administrasi Kota Yogyakarta dan Kabupaten Gunung Kidul. Pola spasial jangkauan pelayanan kesehatan di wilayah DIY dengan mengambil Kota Yogyakarta dan Kabupaten Gunung Kidul telah berhasil dibuat. Hasil pemetaan menunjukkan bahwa Kota Yogyakarta mendominasi fasilitas kesehatan dengan sedikitnya 1 puskesmas disetiap kecamatan. Kesimpulan dalam penelitian ini yaitu persebaran fasilitas kesehatan di Kota Yogyakarta merata dan lokasinya saling berdekatan. Sedangkan Kabupaten Gunung Kidul fasilitas kesehatan didominasi didaerah Kota Wonosari. Wilayah bagian selatan seperti Tanjungsari, Tepus, Girisobo realtif sangat jauh dari akses fasilitas kesehatan.
ANALISIS STRUKTUR DAN NILAI MORAL DALAM NOVEL RANDA BÉNGSRAT KARYA YUS RUSAMSI
Authors: Purnama Indah Rika
Published: November 2023

Penelitian ini bertujuan untuk mengetahui struktur dan nilai moral dalam novel Randa Béngsrat karya Yus Rusamsi. Metode yang digunakan dalam penelitian ini adalah deskriptif analisis dengan menggunakan teknik pengumpulan data telaah pustaka dan analisis Kata Kunci: data. Berdasarkan hasil analisis struktur cerita. Pertama, tema dari novel ini adalah tentang cinta, iman dan perjuangan perempuan; alur yang digunakan dalam novel ini adalah alur mundur; karakter dalam novel ini terdapat 45 karakter. Dari 45 karakter tersebut, satu karakter utama yaitu Ésih. 13 pelaku yang mendampingi pelaku utama (pelaku kedua), dan 31 pelaku tambahan;latar yang terdapat dalam novel ini adalah 68 latar tempat; judul Randa Béngsrat mengacu pada tokoh utama yaitu Ésih, yang memiliki tiga tingkatan makna, yaitu: 1) Randa, 2) Béngsrat, 3) Randa Béngsrat; Sudut pandang yang digunakan dalam novel ini adalah orang ketiga tak terbatas; gaya basa yang digunakan dalam novel ini yaitu 7; tone dalam novel ditemukan ada 10 tone: simbolisme dalam novel ini ditemukan 41 simbol; ironi dalam novel ini ditemukan ironi Struktur Nilai Moral Novel dramatis. Kedua, terdapat 27 nilai moral yang terdapat dalam novel tersebut, yaitu hubungan manusia dengan dirinya sendiri, hubungan manusia dengan manusia lain, dan hubungan manusia dengan Tuhan.
EFEKTIVITAS METODE LATIHAN DRILL OPEN SPIKE DAN BACK ATTACK TERHADAP AKURASI SPIKE DI EKSTRAKURIKULER BOLA VOLI SMK KORPRI MAJALENGKA
Authors: Triyadi Setiawan Dede Triyadi Setiawan
Published: November 2023

This study aims to determine the effectiveness of open spike drill exercises to increase accuracy, to determine the effectiveness of spike back attack drills to increase accuracy and to determine differences in the effect of drill exercises to increase open spike and spike back attack. This study uses an experimental method. The design used is a pretest-posttest control group design. The population in this study were volleyball extracurricular athletes at Korpri Majalengka Vocational School, totaling 40 members. The sampling technique used random sampling, totaling 20 athletes. The data analysis technique uses SPSS for normality, homogeneity uses the Test of Homogeneity of Variances, and t test for hypothesis testing. The results showed that the Effectiveness of Open Spike and Back Attack Drill Practice Methods on Spike Accuracy in Volleyball Extracurricular at SMK Korpri Majalengka. The results of this study are data about the pretest and posttest scores using the SPSS series 16 program with a significant level of 5%. Based on the t-test analysis, it can be seen that there is a significant effect of Drill Open Spike on Spike Accuracy. Which can be seen from the calculated significant value on the t-test of 0, 000 which is greater than 5% (sig < 0.05). Based on the research, the Drill Open Spike training model can be developed and applied in the Drill Open Spike training process in volleyball.
The study of propranolol treatment for hemangioma of infancy- A hospital based observational study
Authors: Khatun Masuda , Sayed MM Abu , Pervin Monira
Published: November 2023

Background: Infantile haemangiomas are the most common tumours of infancy, regularly encountered in dermatology and paediatric practices.

Methods: One hundred patients from Dhaka Medical College Hospital were treated with oral propranolol for IHs between May 2015 and December 2015.

Results: Majority 25(69.45%) patients belonged to age ≤6 months, the mean age was found 4.2±5.0 months. Males were predominant (80.6%). Male female ratio was 4.14:1. Regarding facial segments 10(27.8%) patients had S3. Two (6.0%) patients had trunk lesions. Eyelid was found 6(17.0%). Ulcerated hemangioma was found in 4(12.0%). Mean severity scores were significantly reduces from 4 to 32 weeks when compare with baseline and different follow up.

Conclusion: Majority hemangioma patients belonged to age ≤6 months, mean severity scores were significantly reduced from 4 to 32 weeks when compared with baseline and different follow up.

Journal of Paediatric Surgeons of Bangladesh (2016) Vol. 7 (1): 11-14
Young boy with hematuria followed by acute urinary retention
Authors: Khan Sifat Zereen , Huq Md Ashraf Ul , Hossain Tahmina , Rouf Md Abdur
Published: November 2023

Acute frank hematuria followed by urinary retention in paediatric patients commonly occurs after trauma. A young boy hailing from a lake district of Bangladesh suffering from acute frank hematuria followed by urinary retention and painful abdominal swelling was evaluated by cystoscope. An intra-vesical dead leech was found and removed by a small suprapubic incision under cystoscopic guidance.

Journal of Paediatric Surgeons of Bangladesh (2016) Vol. 7 (1): 20-21
Police Supervision — The Case of Kosovo
Authors: Shishani Fitim
Published: November 2023

Background: The development of social relations in the democratic state of Kosovo necessitates quality regulation by the police. Therefore, the question of developing and implementing the police supervision system in Kosovo is relevant.
Objectives: This research aims to explore the principles underlying the monitoring of police officers in Kosovo, to describe the historical development of the Kosovo police and to charac- terise the prerequisites for the development of police oversight. Furthermore, it aims to draw a comparative analysis between the experiences of Kosovo and the United States in the context of monitoring police performance.
Methods: The research uses methods of analysis (to explore the Kosovo police as a law enforce- ment agency), synthesis (to explore the stages of policy development), comparison (to explore the similarities and differences between the activities), generalisation (to describe the effectiveness of different supervisory institutions), and formal legal analysis (to study the content of the main regulations governing activities).
Results and Conclusions: The research has established that in Kosovo, such a body is represented in the context of the Police Inspectorate. The research highlighted the main areas of activity of internal and external oversight mechanisms designed to combat unethical and illegal behaviour of police officers. It examined the main regulations that establish the rights and obligations of Kosovo Police officers and inspectors and proved that the control mechanisms complement each other in the course of police supervision. In addition, the research examined the experience of police oversight in the United States. The research has established that to increase the effectiveness of monitoring police activities, it is necessary to involve public representatives. It was found that the police system consists of an internal and external mechanism that allows for covering vari- ous areas of police activity and timely detection of violations in them. Also, within the internal control, there are special departments that are part of the police system. The research findings should be used to prepare reforms and strategies to improve police performance.
The Effects of Consumer Cultural Values on Ethical Judgment and Performance of Global Brands Among Young Consumers
Authors: Bahl Angelica , Romanova Irina M. , Noskova Elena V.
Published: November 2023

This study uses well-developed and tested scales to examine differences across two countries in the effects of consumer cultural values on ethical judgment and global brand performance. The study measured consumer attention toward two global brands – Nike and KFC. The research was conducted using over 804 young consumers from Russia and China. The research includes two studies specifically focused on young consumers (18-25) and their attention toward two brands. The first study showed that young Chinese and Russian consumers with strong cultural values are more ethical consumers than unethical. However, consumers who demonstrated strong cultural value such as achievement showed active unethical behavior in both samples. The second study confirmed that two cultural values in young consumers, hedonism and achievement, strongly affected KFC brand performance in both countries. However, young Russian consumers with hedonism and power cultural values strongly affected Nike brand performance, as well as young Chinese consumers with universalism cultural values.
Artificial Intelligence in Marketing Communication: Adoption Challenges and Opportunities Through a Lens of Cognitive Dissonance
Authors: Richards Melanie B.
Published: November 2023

As artificial intelligence (AI) becomes increasingly prevalent, humans and organizations must make decisions regarding its adoption and use. However, the adoption of AI can be a complex process that challenges existing beliefs and practices. Cognitive dissonance, the discomfort that arises when individuals are faced with conflicting beliefs or behaviors, can exist within both the individual and organizational AI adoption journey. This article explores the concept of cognitive dissonance in relation to the adoption and use of AI, particularly when users may not even be aware that they are interacting with AI. By understanding the role of cognitive dissonance in the adoption process, individuals and organizations can make informed decisions that promote its successful integration and potentially lead to greater acceptance of its capabilities.
Pengaruh Pemberian Kombinasi Core Stability Exercise dan Wobble Board Terhadap Keseimbangan Dinamis Pada Anak Sekolah Dasar
Authors: Yasa I Made Astika , Ayu Vitalistyawati Luh Putu
Published: November 2023

Menurunnya minat anak-anak terhadap aktivitas motoric akibat gadget akan menghambat dari proses perkembangan motoric ini terutama pada keseimbangan dinamis. Perlunya diberikan latihan modifikasi untuk dapat membantu mengoptimalkan perkembangan keseimbangan dinamis pada anak. Penelitian ini bertujuan untuk mengetahui pengaruh dari pemberian Core Stability Exercise dan Wobble Board terhadap keseimbangan dinamis pada anak sekolah dasar. Metode penelitian ini pre-eksperimental dengan one group pre-test and post-test design. Alat ukur keseimbangan dinamis yang digunakan adalah Y Balance Test. Sampel pada penelitian ini sejumlah 17 orang yang didapat berdasarkan kriteria inklusi dan eksklusi. Uji Normalitas dengan Shapiro-wilk test menunjukkan p>0,05 pada hasil pre dan post test. Berdasarkan hasil uji Paired Sample T-Test didapatkan hasil p=0,000 yang berarti terdapat peningkatan keseimbangan dinamis pada anak sekolah dasar dengan presentase peningkatan sebesar 11,65%. Sehingga kombinasi dari Core Stability Exercise dan Wobble Board dapat menjadi salah satu modifikasi latihan keseimbangan dinamis pada anak-anak
APPLICATION OF SURAH AR-RAHMAN MUROTTAL THERAPY FOR REDUCING PAIN LEVELS IN DIABETIC ULCER PATIENTS
Authors: Hidayati Anis , Prihati Dyah Restuning
Published: November 2023

A diabetic ulcer is an acute complication that is feared by people with diabetes mellitus. In wound care often patients complain of pain and anxiety. Pain and anxiety begin during the process of removing the dressing and cleaning the wound. Nurses carry out non-pharmacological pain management to reduce pain in patients. Murottal therapy is a distraction technique for someone to read or listen to the holy verses of the Alquran. The aim of the study was to identify the benefits of applying the murottal therapy technique in reducing pain in diabetic ulcer patients undergoing wound care. Descriptive research method with case studies. The subjects of this case study were two patients with diabetic ulcer degrees I, II, and III. The instrument sheet uses an observation sheet of the NRS (Numeric Rating Scale) rating scale. Ar-Rahman murrotal therapy intervention for 3 days with a duration of 10-15 minutes. Respondent I before being given murrottal therapy with a pain scale of 6 (moderate pain). On day 3 there was a decrease in pain scale 3 (mild pain). Respondent II before being given murottal therapy with a pain scale of 5 (moderate pain). On day 3 there was a decrease in the pain scale to 2 (mild pain). The murottal therapy technique was able to reduce the level of pain, which initially experienced a moderate pain scale (4-6) and became mild (1-3).
STUNTING BONE AGE EXAMINATION IN STUNTING CHILDREN IN THE RADIOLOGY INSTALLATION OF SIJUNJUNG HOSPITAL, WEST SUMATRA
Authors: Nansih Livia Ade
Published: November 2023

Bone age maturity is a key component in evaluating a child's growth. Assessment of bone maturity is determined by measuring "Bone Age", namely an X-ray examination of the left wrist bone. Ossification of trabecular bone occurs in a predictable pattern, so that assessment of bone maturity can be made at several ossification centers and then compared to standard radiographic images for males and females. The results of the radiographs are compared with the individual's chronological age as an indicator of the speed of growth, using the ± SD reference it can be concluded that it is in the late or normal category. Examination of a single X-ray on the representative left hand to assess the center of ossification so as to avoid radiation exposure for radiographic examination of all bones. Assessment of hand radiographic analysis can show a correlation with facial growth during puberty. This research is a qualitative descriptive research method with an observational study, conducted on January 27 2023 at the radiology installation of Sijunjung Hospital with a population of stunted children with a sample of seven stunted children, data collection by examining the left manus anterior posterior projection after that the radiograph results evaluated by a radiologist. The results showed that there were three stunted children who did not experience delays in bone age maturity, namely one boy aged 5 years, one boy aged 11 years and one girl aged 13 years and there were four children who were stunted. delayed bone age maturity, namely one girl aged 10 years, two boys aged 10 years and one boy aged 15 years so that further research needs to be done for the factors causing bone age maturity in stunted children.
ANALYSIS OF CRANIUM RADIOGRAPHY RESULTS WITH COMPARISON OF GRID RATIO 8:1 AND RATIOGRID 6:1 TO GET GOOD DENSITY VALUES
Authors: Dewilza Nerifa , Yudha Sagita , Afiifah Mentari
Published: November 2023

Grid has several types of ratios, where each ratio is influenced by the plate, the thickness of the plate, the width of the insulating material or interspace and the absorption of radiation. This can affect the density of the resulting radiograph. Based on the observations, the grid used in the Cranium examination, where the grid ratios that are often found are 8:1 and 6:1 grid ratios. Therefore, the purpose of this study is to determine which grid ratio produces good density and can produce good quality cranium radiographs.

This type of research is quantitative with experimental studies. It was carried out at the Radiology Installation of the Siti Rahmah Islamic Hospital, Padang. In May 2022. This research uses the ratio grid, Phantom Cranium and stepwadge. The results of the radiograph are then measured for the density value using a densitometer and displayed in the form of a table and the graph obtained is displayed in the form of tables and graphs.

The results showed that the radiographic density value of the Cranium Ap grid ratio of 8:1 was 0.69 and the 6:1 grid ratio was 0.75. The radiographic density value of the Cranium Lateral grid ratio of 8:1 is 0.67 and the 6:1 grid ratio is 0.88. From the density value, it can be concluded that the result of using the grid ratio on Cranium examination is good, namely the grid ratio of 8:1.
ANALISIS KUALITAS SOAL KOGNITIF MATERI SISTEM PERNAPASAN MANUSIA
Authors: Khasanah Uswatun , Fitriyah Lina Arifah
Published: November 2023

Evaluasi pembelajaran sebagai kegiatan yang penting untuk mengetahui pencapaian kemampuan belajar peserta didik dalam proses pembelajaran. Berdasarkan observasi diketahui soal evaluasi pembelajaran IPA yang selama ini diberikan kepada peserta didik belum pernah dilakukan analisis berdasarkan empiris. Tidak adanya analisis empiris menunjukkan tidak adanya proses revisi atau pemilahan soal yang valid maupun tidak valid. Atas hal tersebut maka dipandang perlu menganalisis kualitas soal kognitif. Tujuan penelitian ini adalah mendeskripsikan kualitas soal kognitif materi sistem pernapasan pada manusia. Pengembangan ini menggunakan model ADDIE. Soal yang dikembangkan sejumlah 20 soal yang selanjutnya dilakukan validasi yang memuat aspek materi, konstruksi, bahasa dan tampilan. Hasil Penelitian menunjukkan bahwa soal kognitif materi sistem pernapasan manusia dinyatakan memenuhi kualitas sangat baik dengan presentase 95,24% dan dapat dipergunakan dalam evaluasi pembelajaran.

Kata kunci: Analisis Kualitas, Soal Kognitif, Sistem Pernapasan Manusia
The Effect of Receivable Turnover on Working Capital of Automotive Companies During The COVID-19 Pancemic, Through Liquidity as an Intervening Variable
Authors: Anfas  , Rahim Abdul Rahman , Nurdin Djayani , Hendrian  , Safitri Julia
Published: November 2023

This study aims to determine the effect of accounts receivable turnover on working capital either directly or indirectly through liquidity as an intervening variable. The research was conducted on automotive companies on the Indonesia Stock Exchange (IDX) for the 2019-2022 period. The research data is secondary data taken from the company's financial statements. While data analysis using regression analysis. The results of the study show that receivables turnover, both directly and indirectly, has no significant effect on the company's working capital during the economic crisis due to the COVID-19 pandemic. Receivable turnover also has no significant effect on the liquidity of automotive companies on the IDX. Likewise, liquidity has no significant effect on the company's working capital.
Iceberg Exploration And The “U” Process As A Learning Method In Religious Moderation Strengthening Training
Authors: Hamid Abdul , Rahim Abdul Rahman , Sultan Zulkifli , Ahmadi Slamet
Published: November 2023

This study evaluates the effectiveness of the Iceberg analysis and U-process methods in training to strengthen religious moderation by evaluating the reaction and learning level of the Kirkpatrick method. Survey research and descriptive analysis were used to determine training effectiveness. The population is 90 people, and the sample is 73 using the Morgan and Krejcie Sample formula. The validity and reliability of the instrument and the Paired Sample T-Test were tested on learning outcomes. The Iceberg analysis and U process learning processes carried out the descriptive analysis. The findings of the research show that training evaluation at the reaction level is in the very good quadrant and is good for all aspects of the organizer and teacher; learning outcomes show a significant increase; and at the level of results, the learning process with the Iceberg and U-Process methods is significant in increasing the knowledge and abilities of participants. The results of the training show that it is effective. This research focuses on examining the learning aspects of training and using them to evaluate the effectiveness of training outcomes.
Determinants of Coffee Commodity Exports as An Effort of Post-Pandemic Economic Recovery COVID-19 in Indonesia
Authors: Budi Darmanto Erlambang , Riau Dwi Putranto
Published: November 2023

This study aims to analyze the factors of gross domestic product, exchange rate, total consumption, and export value on Indonesia's export performance of coffee beans after the Covid-19 pandemic in Indonesia's 14 trading partner countries (Egypt, Italy, the Philippines, Thailand, Belgium, Germany, Japan, Russia, England, China, India, Malaysia, Singapore, and United States of America). This study uses secondary data and Generalized Method of Moment (GMM).Our findings imply that: 1) the variable total consumption shows a positive and insignificant relationship, 2) the variables of GDP, and 3) the exchange rates variable shows a negative and significant relationship with coffee commodity exports, and the variable value of exports shows a negative and insignificant relationship with exports of coffee commodities. Analyzed the factors of gross domestic product, exchange rate, total consumption, and export value on the export performance of Indonesian coffee beans after the Covid-19 pandemic in 14 of Indonesia's trading partners for the last 11 years, namely 2012-2023
Opportunities And Challenges For Indonesian Halal Certification
Authors: Sani Abu
Published: November 2023

This research aims to look at the opportunities and challenges of halal certification in Indonesia. The research method used is qualitative with a descriptive approach. Indonesian people are currently competing to obtain halal guarantee letters or halal certificates, so the government through related institutions continues to strive to help business actors to be able to obtain halal product guarantees from the government. So that the work on halal certification can develop over time. This article aims to analyze the opportunities and challenges of halal certification in Indonesia in the period after the issuance of regulations regarding Halal Product Guarantee (JPH). Halal certification was initially under the authority of the Indonesian Ulema Council (MUI), then after the JPH Law was issued, halal certification was delegated to BPJPH (Halal Product Guarantee Organizing Agency) which is under the control of the Ministry of Religion of the Republic of Indonesia. This could also be imitated by various changes in policies related to halal certification. With the existence of BPJPH, halal certification for every business actor becomes mandatory. Research on halal certification is still relevant today.
Light-driven reversible charge transfers from ITO nanocrystals
Authors: Rebecchi Luca , Rubino Andrea , Camellini Andrea , Kriegel Ilka
Published: November 2023

The combination of semiconductors and redox active molecules for light-driven energy storage systems has emerged as a powerful solution for the exploitation of solar batteries. On account of this, transparent conductive oxide (TCO) nanocrystals (NCs) demonstrated to be interesting materials, thanks to the photo-induced charge accumulation enabling light harvesting and storage. The charge transfer process after light absorption, at the base of the proper use of these semiconductors, is a key step, often resulting in non-reversible transformations of the chemicals involved. However, if considering the photocharging through TCO NCs not only as a charge provider for the system but potentially as part of the storage role, the reversible transformation of the redox compound represents a crucial aspect. In this paper, we explore the possible interaction of indium tin oxide (ITO) NCs and typical redox mediators commonly employed in catalytic applications with a twofold scope of enhancing or supporting the light-induced charge accumulation on the metal oxide NC side and controlling the reversibility of the whole process. The work presented focuses on the effect of the redox properties on the doped metal oxide response, both from the stability point of view and the photodoping performance, by monitoring the changes in the optical behavior of ITO/redox hybrid systems upon ultraviolet illumination.
Cardiac remodeling on echocardiogram is related to contrast-associated acute kidney injury after coronary angiography: a cross-section study
Authors: Chen Qingqing , Li Duanbin , Jiang Hangpan , Hu Tianli , Tao Yecheng , Du Changqing , Zhang Wenbin
Published: November 2023

Background

Cardiac dysfunction is a well-established risk factor for contrast-associated acute kidney injury (CA-AKI). Nevertheless, the relationship between cardiac remodeling, as assessed by echocardiography, and CA-AKI remains uncertain.

Method

A total of 3,241 patients undergoing coronary angiography (CAG) with/without percutaneous coronary intervention (PCI) were enrolled in this retrospective study. Collected echocardiographic parameters were normalized by body surface area (BSA) and divided according to quartile, including the left ventricular internal end-diastolic diameter index (LVIDDI), left ventricular internal end-systolic diameter index (LVIDSI), and left ventricular mass index (LVMI). Logistic regression analysis was conducted to ascertain the association between structural parameter changes and CA-AKI. Further investigation was performed in different subgroups.

Results

The mean age of the participants was 66.6 years, and 16.3% suffered from CA-AKI. LVIDSI [≥22.9 mm/m2: OR = 1.953, 95%CI (1.459 to 2.615), P < 0.001], LVIDDI [≥33.2 mm/m2: OR = 1.443, 95%CI (1.087 to 1.914), P = 0.011], and LVMI [≥141.0 g/m2: OR = 1.530, 95%CI (1.146 to 2.044), P = 0.004] in quartile were positively associated with CA-AKI risk in general (all P for trend <0.05). These associations were consistent when stratified by age, left ventricular ejection fraction, estimated glomerular filtration rate, and N-terminal brain natriuretic peptide (all P for interaction >0.05). The presence of eccentric hypertrophy [OR = 1.400, 95%CI (1.093 to 1.793), P = 0.008] and the coexistence of hypertrophy and dilation [OR = 1.397, 95%CI (1.091 to 1.789), P = 0.008] carried a higher CA-AKI risk.

Conclusion

The presence of cardiac remodeling, assessed by echocardiography, is associated with a higher risk of CA-AKI.
The impact of global value chain embedding on the upgrading of China’s manufacturing industry
Authors: Fu Qingwei
Published: November 2023

In the current international trade characterized by global value chains (GVCs), to improve the trade interests of China’s manufacturing industry and change the unfavorable situation of “big but not strong,” industrial upgrading is an important issue that needs to be solved urgently. Based on the analysis of the impact of embedding in GVCs on the acquisition of trade benefits, the paper empirically tests the impact of embedding GVCs on manufacture upgrading by using industry segmentation data of China’s manufacturing industry from the year 2000 to 2014 in the world input–output database. The research shows that 1) from 2000 to 2014, forward and backward participation increased from 11.2% and 15.2% to 14.6% and 15.9%, respectively; China’s manufacturing industry mainly participates in the GVC in a backward way, which significantly improves trade interests; 2) both forward participation and backward participation in the GVC are conducive to the increase of trade benefits and are positive at the 5% level, which has a significant driving effect on the upgrading of the manufacturing industry; and 3) heterogeneity testing shows that capital-intensive, technology-intensive, and high-tech industries gain significant trade benefits, and embedding GVCs is more conducive to upgrading. Therefore, integrating into the GVC at a higher level is the direction to promote the upgrading of China’s manufacturing industry.
Modeling of intelligent controllers for solar photovoltaic system under varying irradiation conditions
Authors: Khan Malhar , Raza Muhammad Amir , Jumani Touqeer Ahmed , Mirsaeidi Sohrab , Ali Aamir , Abbas Ghulam , Touti Ezzeddine , Alshahir Ahmed
Published: November 2023

The increasing demand for solar renewable energy resources, driven by the global energy crisis and the depletion of conventional energy sources, has underscored the importance of harnessing solar energy. Solar photovoltaic (PV) systems, however, exhibit nonlinear output power due to their weather-dependent nature, impacting overall system efficiency. This study focuses on the development and comparative analysis of three intelligent Maximum Power Point Tracking (MPPT) controllers using the MATLAB Simulink. The controllers employ distinct methodologies, namely, Artificial Neural Networks (ANN), Adaptive Neural and Fuzzy Inference System (ANFIS), and Fuzzy Logic Controller (FLC). The results demonstrate that ANFIS achieved the highest accuracy at 99.50%, surpassing ANN and FLC with accuracies of 97.04% and 98.50%, respectively, thus establishing ANFIS as the superior MPPT controller. Additionally, the positives and negatives of all three MPPT-based algorithms are also compared in this work.
Leveraging machine learning algorithms for improved disaster preparedness and response through accurate weather pattern and natural disaster prediction
Authors: Jain Harshita , Dhupper Renu , Shrivastava Anamika , Kumar Deepak , Kumari Maya
Published: November 2023

Globally, communities and governments face growing challenges from an increase in natural disasters and worsening weather extremes. Precision in disaster preparation is crucial in responding to these issues. The revolutionary influence that machine learning algorithms have in strengthening catastrophe preparation and response systems is thoroughly explored in this paper. Beyond a basic summary, the findings of our study are striking and demonstrate the sophisticated powers of machine learning in forecasting a variety of weather patterns and anticipating a range of natural catastrophes, including heat waves, droughts, floods, hurricanes, and more. We get practical insights into the complexities of machine learning applications, which support the enhanced effectiveness of predictive models in disaster preparedness. The paper not only explains the theoretical foundations but also presents practical proof of the significant benefits that machine learning algorithms provide. As a result, our results open the door for governments, businesses, and people to make wise decisions. These accurate predictions of natural catastrophes and emerging weather patterns may be used to implement pre-emptive actions, eventually saving lives and reducing the severity of the damage.
Availability of state-level climate change projection resources for use in site-level risk assessment
Authors: Rabinowitz Hannah S. , Dahodwala Sophia , Baur Sophie , Delgado Alison
Published: November 2023

In recent years, incorporating climate change considerations has become an important focus of organizations’ resilience planning and risk assessment efforts, including United States federal agencies. This has led to an increasing demand for higher-resolution and higher-quality climate projection information that is easy to understand for non-expert users. In particular, there is a demand for information about how climate change may affect high-impact, low-frequency (HILF) hazards that are central to risk assessments focused on infrastructure. While national-level resources like the National Climate Assessment provide information on climate impacts for different sectors and regions in the United States, downscaled information with location-specific context is often required for site-level resilience planning. As higher-resolution and higher-quality climate resources continue to be developed at the state level, it is imperative to understand ongoing and planned efforts, as well as key drivers for developing these state-level resources. Based primarily on stakeholder input from climate experts from 31 states, we identify key state-level climate resources, as well as drivers accelerating the development of these resources. We assess the availability of climate change resources, specifically those with information about HILF events that have been developed at the state level and can support users in conducting site-level resilience planning. We identify three key drivers or predictors for the development of climate change resources at the state level: (1) existence of state laws, mandates, Executive Orders, and other state policies, (2) existence of university partnerships; and (3) the makeup of the stakeholder groups (in terms of dominant discipline/expertise) participating in the effort. The diverse state strategies and resources surveyed in this study could support the incorporation of higher-resolution climate information into site-level planning.
Taking Tiger Worm Toilets to scale: opportunities and challenges
Authors: Sioné Laure , Gibson Walter , Beckett Patrick , Oak Ajeet , Sathre Roger , Furlong Claire , Bastable Andy , Batarda Carlos , Templeton Michael R.
Published: November 2023

Tiger Worm Toilets (TWTs) are a relatively recent innovation in sanitation technology, with the potential to offer affordable and safely managed on-site sanitation for underserved communities in line with Sustainable Development Goal 6. This article, authored by members of the International Worm-Based Sanitation Association (IWBSA), presents the state-of-the-art in TWT construction and operation based on frontier global experiences to-date, stemming from both knowledge from literature and the practical knowledge imparted by the authors, who were involved in the birth of this technology and are still active in the research and deployment of it today. The focus of this paper is on the implementation of TWTs to solve sanitation challenges in least-developed and lower-middle income countries specifically. The design of TWTs can be adapted to a wide range of environmental conditions including high water tables and rocky ground conditions, and in both rural and urban contexts. The challenge for TWTs therefore lies primarily in creating opportunities for scaling the uptake of this promising technology. Our article discusses the key barriers to this, identified to be broadly categorised as user preference, capacity and capability building, and governmental support–and proposes how to overcome these.
Evolutionary insights and expression dynamics of the CaNFYB transcription factor gene family in pepper (Capsicum annuum) under salinity stress
Authors: Abd El Moneim Diaa , Mansour Hassan , Alshegaihi Rana M. , Safhi Fatmah Ahmed , Alwutayd Khairiah Mubarak , Alshamrani Rahma , Alamri Amnah , Felembam Wessam , Abuzaid Amani Omar , Magdy Mahmoud
Published: November 2023

Introduction: The Capsicum annuum nuclear factor Y subunit B (CaNFYB) gene family plays a significant role in diverse biological processes, including plant responses to abiotic stressors such as salinity.

Methods: In this study, we provide a comprehensive analysis of the CaNFYB gene family in pepper, encompassing their identification, structural details, evolutionary relationships, regulatory elements in promoter regions, and expression profiles under salinity stress.

Results and discussion: A total of 19 CaNFYB genes were identified and subsequently characterized based on their secondary protein structures, revealing conserved domains essential for their functionality. Chromosomal distribution showed a non-random localization of these genes, suggesting potential clusters or hotspots for NFYB genes on specific chromosomes. The evolutionary analysis focused on pepper and comparison with other plant species indicated a complex tapestry of relationships with distinct evolutionary events, including gene duplication. Moreover, promoter cis-element analysis highlighted potential regulatory intricacies, with notable occurrences of light-responsive and stress-responsive binding sites. In response to salinity stress, several CaNFYB genes demonstrated significant temporal expression variations, particularly in the roots, elucidating their role in stress adaptation. Particularly CaNFYB01, CaNFYB18, and CaNFYB19, play a pivotal role in early salinity stress response, potentially through specific regulatory mechanisms elucidated by their cis-elements. Their evolutionary clustering with other Solanaceae family members suggests conserved ancestral functions vital for the family’s survival under stress. This study provides foundational knowledge on the CaNFYB gene family in C. annuum, paving the way for further research to understand their functional implications in pepper plants and relative species and their potential utilization in breeding programs to enhance salinity tolerance.
Chronic granulomatous disease in the United Arab Emirates: clinical and molecular characteristics in a single center
Authors: Al Kuwaiti Amna Ali , Al Dhaheri Ahmed Darwaish , Al Hassani Moza , Ruszczak Zbigniew , Alrustamani Ahmad , Abuhammour Walid , El Ghazali Gehad , Al-Hammadi Suleiman , Shendi Hiba M.
Published: November 2023

Background

Chronic granulomatous disease (CGD) is a genetic disorder caused by defective oxidative burst within phagocytes, manifesting as recurrent, severe infections as well as hyperinflammation.

Objective

This is the first report from the United Arab Emirates (UAE) to describe the demographic, clinical, laboratory, radiological, and genetic characteristics of patients with CGD.

Methods

This is a retrospective study that was conducted at Tawam Hospital in the UAE on patients with confirmed CGD between 2017 and 2022.

Results

A total of 14 patients were diagnosed with CGD, of whom 13 patients had autosomal recessive (AR) CGD due to NCF1 deficiency. Consanguinity was noted in all patients with AR CGD, whereas positive family history was identified in 50% of cases. The median age of onset of symptoms was 24 months, while the median age at diagnosis was 72 months. Lymphadenitis was the most common clinical feature identified in 71% of patients. Other common infectious manifestations included abscess formation (57%), pneumonia (50%), invasive aspergillosis (21%), oral thrush (14%), and sepsis (14%). Disseminated trichosporonosis was reported in one patient. Autoimmune and inflammatory manifestations included celiac disease in two patients, diabetes mellitus and asymptomatic colitis in one patient each. Genetic analysis was performed in all patients; NCF1 deficiency was diagnosed in 13 (93%) patients, with c.579G>A being the most prevalent pathogenic variant identified. The treatment modalities, as well as treatment of acute infections, treatment modalities included antimicrobial prophylaxis in 12 (86%) patients and hematopoietic stem cell transplant in six patients (42%).

Conclusion

This is the first report from the UAE describing the clinical and molecular characteristics of patients with CGD. The homozygous variant c.579G>A causing NCF1 deficiency can be considered as a founder mutation for AR CGD in the UAE.
Recent advance in the development of tuberculosis vaccines in clinical trials and virus-like particle-based vaccine candidates
Authors: Zhou Fangbin , Zhang Dongmei
Published: November 2023

Tuberculosis (TB) remains a serious public health threat around the world. An effective vaccine is urgently required for cost-effective, long-term control of TB. However, the only licensed vaccine Bacillus Calmette-Guerin (BCG) is limited to prevent TB for its highly variable efficacy. Substantial progress has been made in research and development (R&D) of TB vaccines in the past decades, and a dozen vaccine candidates, including live attenuated mycobacterial vaccines, killed mycobacterial vaccines, adjuvanted subunit vaccines, viral vector vaccines, and messenger RNA (mRNA) vaccines were developed in clinical trials to date. Nevertheless, many challenges to the successful authorization for the use and deployment of an effective tuberculosis vaccine remain. Therefore, it is still necessary and urgent to continue exploring new vaccine construction approaches. Virus-like particles (VLPs) present excellent prospects in the field of vaccine development because of their helpful immunological features such as being safe templates without containing viral nucleic acid, repetitive surface geometry, conformational epitopes similar to natural viruses, and enhancing both innate and adaptive immune responses. The marketization process of VLP vaccines has never stopped despite VLP vaccines face several shortcomings such as their complex and slow development process and high production cost, and several VLP-based vaccines, including vaccines against Human papillomavirus (HPV), Hepatitis B Virus (HBV) and malaria, are successfully licensed for use at the market. In this review, we provide an update on the current progress regarding the development of TB vaccines in clinical trials and seek to give an overview of VLP-based TB vaccine candidates.
Dynamics of necroptosis in kidney ischemia-reperfusion injury
Authors: Pefanis Aspasia , Bongoni Anjan K. , McRae Jennifer L. , Salvaris Evelyn J. , Fisicaro Nella , Murphy James M. , Ierino Francesco L. , Cowan Peter J.
Published: November 2023

Necroptosis, a pathway of regulated necrosis, involves recruitment and activation of RIPK1, RIPK3 and MLKL, leading to cell membrane rupture, cell death and release of intracellular contents causing further injury and inflammation. Necroptosis is believed to play an important role in the pathogenesis of kidney ischemia-reperfusion injury (IRI). However, the dynamics of necroptosis in kidney IRI is poorly understood, in part due to difficulties in detecting phosphorylated MLKL (pMLKL), the executioner of the necroptosis pathway. Here, we investigated the temporal and spatial activation of necroptosis in a mouse model of unilateral warm kidney IRI, using a robust method to stain pMLKL. We identified the period 3-12 hrs after reperfusion as a critical phase for the activation of necroptosis in proximal tubular cells. After 12 hrs, the predominant pattern of pMLKL staining shifted from cytoplasmic to membrane, indicating progression to the terminal phase of necroptotic cell death. Mlkl-ko mice exhibited reduced kidney inflammation at 12 hrs and lower serum creatinine and tubular injury at 24 hrs compared to wild-type littermates. Interestingly, we observed increased apoptosis in the injured kidneys of Mlkl-ko mice, suggesting a relationship between necroptosis and apoptosis in kidney IRI. Together, our findings confirm the role of necroptosis and necroinflammation in kidney IRI, and identify the first 3 hrs following reperfusion as a potential window for targeted treatments.
Characterization of wind turbine flow through nacelle-mounted lidars: a review
Authors: Letizia Stefano , Brugger Peter , Bodini Nicola , Krishnamurthy Raghavendra , Scholbrock Andrew , Simley Eric , Porté-Agel Fernando , Hamilton Nicholas , Doubrawa Paula , Moriarty Patrick
Published: November 2023

This article provides a comprehensive review of the most recent advances in the planning, execution, and analysis of inflow and wake measurements from nacelle-mounted wind Doppler lidars. Lidars installed on top of wind turbines provide a holistic view of the inflow and wake characteristics required to characterize and optimize wind turbine performance, carry out model validation and calibration, and aid in real-time control. The need to balance the enhanced capabilities and limitations of lidars compared to traditional anemometers inspired a broad variety of approaches for scan design and wind reconstruction, which we discuss in this review. We give particular emphasis to identifying common guidelines and gaps in the available literature with the aim of providing an exhaustive picture of the state-of-the-art techniques for reconstructing wind plant flow using nacelle-mounted lidars.
Gastric and colonic metastases of malignant melanoma diagnosed during endoscopic evaluation of symptomatic anemia presenting as angina: a case report
Authors: Amaris Manuel A. , Kallas Henrique E. , Gonzalo David H. , Orlando Frank A.
Published: November 2023

A 72-year-old man visited cardiology for exertional chest pain, lightheadedness, and fatigue. Six years prior, he was surgically treated for cutaneous malignant melanoma of the lower back. After a negative cardiac work-up, primary care diagnosed severe iron deficiency anemia. Emergent upper and lower gastrointestinal (GI) endoscopy revealed simultaneous melanoma metastases to the stomach and colon with discrete macroscopic features. Metastatic disease, including brain, lung, and bone, was discovered on imaging. Treatment included immunotherapy with nivolumab and stereotactic radiosurgery of the brain metastases, and our patient has remained in continued remission even after 2 years. Melanoma with GI tract (GIT) metastasis has a poor prognosis and rarely presents symptomatically or with synchronous gastric and colonic lesions. This case illustrates the importance of early primary care involvement to expedite work-up for multifocal GI metastases in patients with a remote melanoma history presenting with symptoms related to iron deficiency anemia (IDA).
A Wohlfahrtiimonas chitiniclastica with a novel type of blaVEB–1-carrying plasmid isolated from a zebra in China
Authors: Guan Jiayao , Zhou Wei , Guo Jingyi , Zheng Lin , Lu Gejin , Hua Fuyou , Liu Mingwei , Ji Xue , Sun Yang , Zhu Lingwei , Guo Xuejun
Published: November 2023

Background

Wohlfahrtiimonas chitiniclastica is an emerging fly-borne zoonotic pathogen, which causes infections in immunocompromised patients and some animals. Herein, we reported a W. chitiniclastica BM-Y from a dead zebra in China.

Methods

The complete genome sequencing of BM-Y showed that this isolate carried one chromosome and one novel type of blaVEB–1-carrying plasmid. Detailed genetic dissection was applied to this plasmid to display the genetic environment of blaVEB–1.

Results

Three novel insertion sequence (IS) elements, namely ISWoch1, ISWoch2, and ISWoch3, were found in this plasmid. aadB, aacA1, and gcuG were located downstream of blaVEB–1, composing a gene cassette array blaVEB–1–aadB–aacA1–gcuG bracketed by an intact ISWoch1 and a truncated one, which was named the blaVEB–1 region. The 5′-RACE experiments revealed that the transcription start site of the blaVEB–1 region was located in the intact ISWoch1 and this IS provided a strong promoter for the blaVEB–1 region.

Conclusion

The spread of the blaVEB–1-carrying plasmid might enhance the ability of W. chitiniclastica to survive under drug selection pressure and aggravate the difficulty in treating infections caused by blaVEB–1-carrying W. chitiniclastica. To the best of our knowledge, this is the first report of the genetic characterization of a novel blaVEB–1-carrying plasmid with new ISs from W. chitiniclastica.