bluuebunny/crossref_metadata_2025 huggingface dataset:
Seasonality Patterns of Internet Searches on Mental Health: Exploratory Infodemiology Study (Preprint)
Authors: Soreni Noam , Cameron Duncan H , Streiner David L , Rowa Karen , McCabe Randi E
Published: November 2018

BACKGROUND

The study of seasonal patterns of public interest in psychiatric disorders has important theoretical and practical implications for service planning and delivery. The recent explosion of internet searches suggests that mining search databases yields unique information on public interest in mental health disorders, which is a significantly more affordable approach than population health studies.

OBJECTIVE

This study aimed to investigate seasonal patterns of internet mental health queries in Ontario, Canada.

METHODS

Weekly data on health queries in Ontario from Google Trends were downloaded for a 5-year period (2012-2017) for the terms “schizophrenia,” “autism,” “bipolar,” “depression,” “anxiety,” “OCD” (obsessive-compulsive disorder), and “suicide.” Control terms were overall search results for the terms “health” and “how.” Time-series analyses using a continuous wavelet transform were performed to isolate seasonal components in the search volume for each term.

RESULTS

All mental health queries showed significant seasonal patterns with peak periodicity occurring over the winter months and troughs occurring during summer, except for “suicide.” The comparison term “health” also exhibited seasonal periodicity, while the term “how” did not, indicating that general information seeking may not follow a seasonal trend in the way that mental health information seeking does.

CONCLUSIONS

Seasonal patterns of internet search volume in a wide range of mental health terms were observed, with the exception of “suicide.” Our study demonstrates that monitoring internet search trends is an affordable, instantaneous, and naturalistic method to sample public interest in large populations and inform health policy planners.
The U.S. Refrigerated Orange Juice Market: A Competitive Profile
Authors: Datta Y.
Published: November 2018

Porter links high market share with cost leadership strategy which is based on the idea of competing on a price that is lower than that of the competition. But, customer-perceived quality—not low cost—should be the foundation of competitive strategy, because it is far more vital to long-term competitive position and profitability than any other factor. So, a superior alternative is to offer better quality vs. the competition.

In most consumer markets a business seeking market share leadership should try to serve the middle class by competing in the mid-price segment; and offering quality better than that of the competition: at a price somewhat higher, to signify an image of quality, and to ensure that the strategy is both profitable and sustainable in the long run.

Quality, however, is an intricate concept consumers generally find difficult to understand. So, they often use relative price and a brand’s reputation as a symbol of quality.

Total U.S. Refrigerated Orange Juice retail sales for 2008 were $2.6 Billion. There were ten package sizes ranging all the way from 6 oz to 128 oz. Of these the 64- and 59-oz size captured about two-thirds of the market at 66%.

It is a very competitive market with 142 brands in 2008. However, we have focused analysis on 32 brands whose 64oz- or 59oz-pack sales were over $1Million.

We tested two hypotheses: (1) That a market leader is likely to compete in the mid-price segment, and (2) That the unit price of the market leader is likely to be somewhat higher than that of the nearest competition. Employing U.S. retail sales data for 2008 and 2007, we found that the results supported both hypotheses for 2008, as well as 2007.

We also found strong support for the idea, that relative price is a strategic variable.

We compared the results of this project with four similar studies: the U.S. Men’s Shaving Cream market, the U.S. Beer market, the U.S. Shampoo market, and the U.S. Shredded/Grated Cheese market. We found the results to be very similar, indicating a pattern emerging for consumer markets.

Finally, we discovered five strategic groups in the industry.
The Effect of Biopsychosocial Variables in Fatigue in Patients with Hemoglobinopathies
Authors: Aslani Eleni F. , Lyrakos Georgios N. , Vini Dimitra , Drosou-Servou Marouso , Tsironi Maria
Published: November 2018

Purpose: The purpose of the present study was to explore the biopsychosocial variables affecting fatigue in patients with hemoglobinopathies. Methods: 102 patients undergoing transfusion treatment from one hospital in Athens, Greece participated in the study. Fatigue was measured with the Multidimensional Fatigue Inventory (MFI), quality of life with the Euro5D thermometer as self-perceived health and psychological variables with the Depression, Anxiety and Stress Scale (DASS 21). Statistical analysis was performed with SPSS21. Results: 63 were females (61,4%) and 39 males (38,6%). The mean age of the sample was 41.7±9.2 years, while the majority of participants were patients with a diagnosis of homozygous ?-Thalassemia (81.4%). Multivariate analysis revealed 6 independent models for each dimension of fatigue, while every one of the five dimensions of MFI as well the total score of the inventory, revealed a different model of correlations with mixed variables, related with disease complications, adherence to treatment, sex, the self-perceived quality of life, as well as the qualitative characteristics of fatigue related with disease complications. Conclusions: Fatigue has been identified as a very common symptom in patients with thalassemia with many variables affecting it in this population. Our results broadens the evidence regarding fatigue in hemoglobinopathies and leads us to the need for distinguishing the etiologies leading to fatigue in hemoglobinopathies since it is an important factor affecting HPQoL. Longitudinal studies are needed in order to understand the path of fatigue and the factors influencing the condition.
REVIEW OF IPOMOEA PES-TIGRIDIS L.: ETHNO BOTANICAL CHARACTERISTICS, PHARMACOLOGICAL ACTIVITIES
Authors: Venkateshan N. , Subramaniyam M. , Santhanakumar M.
Published: November 2018

Nowadays there is a need for scientific justification of plants that have been used in traditional medicine because of loss of information, improvement of therapy and deforestation that is taking place. The majority of the natural products are compounds biosynthetically derived from primary metabolites and are generally categorized as secondary metabolites. These are the major sources of the pharmaceutical industry to discover novel drugs. The basis for interest in natural product chemistry serves as a lead compound for newer drugs, give as much information on possible mechanism and thus on the molecular origin and basis of diseases. Natural products are permanent challenges with respect to total synthesis and stimulate the development of new reagents and reactions. The present study has been taken up to review one of the ethno medicinal significant of Ipomoea pes-tigridis L plant belonging to the family convolvulaceae. The ethno medical information of the plant reveals that the herb Ipomoea pes-tigridis Linn was used as an antidote to dogbite, boils and carbuncles, the leaves were applied as a poultice for boils, carbuncles and sores. The root of this plant was found to possess purgative action. The phytochemical studies on the leaves have been reported for the presence of carbohydrates, proteins and resins.
EVALUATION OF ANTI-ASTHMATIC ACTIVITY OF METHANOLIC EXTRACT OF BERLERIA PRIONITIS LINN. AERIAL PARTS
Authors: S. Manekar Snehal , S. Charde Manoj
Published: November 2018

Objective: The aim of the present study is to evaluate the aerial parts of a plant of Barleria prionitis Linn., for its antiasthmatic activity with the separation of active moieties.Methods: Adult wistar albino rats were used for the anti-inflammatory study. Histamine-induced bronchospasm was conducted on isolated goat trachea.Results: The dried and powdered aerial parts of Berleria prionitis was extracted with continuous soxhlet extraction with Petroleum ether (40-60 ° C), Chloroform, Ethyl acetate, Acetone, Methanol, and Hydroalcoholic solvents. Preliminary phytochemical screening of all extracts was done. Preliminary animal studies by In vitro isolated goat trachea chain preparation of all extracts were done to find out the potent extract. In this study, the methanolic extract of aerial parts of Berleria prionitis was found to be potent comparative to another extract. The results of carrageenan induced rat paw oedema model indicated the dose-dependant anti-inflammatory activity. As compared to standard drug (Indomethacin), methanolic extract showed similar activity which was found to be statistically significant (P<0.0001). The extent of DPPH radical scavenging was determined by calculated the IC50 value of methanolic extract Berleria prionitis (133.5) compared with the Ascorbic acid (114.7) taken as standard. In the present study, the histamine-induced dose-dependent contraction of goat tracheal chain was significantly inhibited (p<0.001) by methanolic extract of aerial parts of Berleria prionitis (200 μg/ml). Thus the present study revealed that the methanolic extract of Berleria prionitis (MEBP) has significant antihistaminic (H1 receptor antagonist) activity.Conclusion: In view the fact that tribal have well experienced the antiasthmatic effects of the roots of Barleria prionitis Linn. The results of our study, for the first time, show that the methanolic extract of aerial parts of Berleria prionitis Linn. possesses antioxidant, anti-inflammatory, Bronchodilator properties and therefore can be used for the antiasthmatic treatment.
Pembatalan Nikah karena Nikah tanpa Izin Wali (Studi terhadap Putusan Mahkamah Syarâ€™iyah Sigli Nomor 246/Pdt.G/2012/MS-Sgi)
Authors: M. Yunus Fakhrurrazi , Dewi Arlina Dewi Arlina
Published: November 2018

Perkara pembatalan nikah pada Putusan Mahkamah Syarâ€™iyah Sigli Nomor 246/Pdt.G/2012/MS-Sgi yang mana Pemohon selaku ayah kandung dari Termohon II mengajukan permohonan pembatalan nikah karena pernikahan tersebut dilaksanakan tanpa izin dari Pemohon. Namun pernikahan tersebut telah tercatat di Kantor Urusan Agama Sigli dengan dinikahkan oleh wali hakim. Penelitian ini bertujuan untuk mengetahui alasan hakim dalam mengabulkan permohonan pembatalan perkawinan Nomor 246/Pdt.G/2012/MS-Sgi dan menganalisis tinjauan hukum Islam terhadap pembatalan nikah tersebut. Dalam penelitian ini Penulis menggunakan metode deskriptif-analisis. Hasil penelitian menunjukkan bahwa Hakim dalam mengabulkan perkara Nomor 246/Pdt.G/2012/MS-Sgi dengan beberapa pertimbangan di antaranya; Termohon II telah menutup-nutupi keadaan wali yaitu dengan memalsukan surat izin wali dan mengatakan bahwa walinya mafqud, serta tidak adanya surat putusan dari Mahkamah Syarâ€™iyah Sigli yang menyatakan tentang keadhalan wali. Sedangkan menurut hukum Islam, seharusnya hakim juga mempertimbangkan alasan Termohon I dan Termohon II memalsukan surat izin orangtua dan mengatakan bahwa wali Termohon II mafqud, itu disebabkan karena wali Termohon II tidak menyetujui pernikahan Termohon I dan Termohon II karena alasan yang tidak syarâ€™i.
Faktor-Faktor terjadinya Poliandri di Masyarakat (Studi Kasus di Kabupaten Pidie Jaya)
Authors: Misran Misran , Muza Agustina Muza Agustina
Published: November 2018

Poliandri adalah sistem perkawinan seorang wanita yang mempunyai suami lebih dari satu orang dalam waktu yang bersamaan. Di kecamatan Trienggadeng Kabupaten Pidie Jaya terjadi empat pernikahan Poliandri. Berdasarkan hal-hal tersebut maka dalam penelitian ini penulis mengkaji apa faktor-faktor terjadi poliandri dan bagaimana upaya penanggulangan poliandri di Kecamatan Trienggadeng Kabupaten Pidie Jaya. Untuk memperoleh jawaban dari hal tersebut maka dalam penelitian ini penulis menggunakan metode penelitian lapangan (field research). Adapun hasil dari penelitian ini adalah pertama faktor-faktor terjadi poliandri yaitu aspek ekonomi, jarak dengan suami yang jauh, aspek tidak terpenuhi nafkah lahir dan batin, aspek usia suami yang sudah lanjut, aspek tidak harmonis di rumah tangga, Aspek kurangnya iman dan lemahnya pemahaman agama sebagai kontrol sosial. Upaya pemerintah untuk menanggulangi poliandri adalah KUA melakukan sosialisi tentang hukum munakahat dan UU tentang perkawinan kepada masyarakat, serta menyampaikan tentang ketentuan-ketentuan hukum perkawinan syariah, dan hukum positif saat melaksanakan kursus calon pengantin.
Ijtihad terhadap Dalil Qathâ€™i dalam Kajian Hukum Islam
Authors: Saâ€™dan Saifuddin
Published: November 2018

Lapangan ijtihad sangat luas dalam fiqh. Para ulama sepakat tentang hal tersebut pada hal-hal yang tidak ada nash ataupun pada dalalah yang masih dhanni. Tetapi pada persoalan yang telah ada nash dan yang bersifat qathâ€™i al-dalalah urusan yang menjadi perbedaan para ulama. Hal ini dikarenakan adanya beberapa ijtihad, khususnya Umar, yang melakukan ijtihad terhadap hukum yang telah ada nashnya dan juga pada dalil yang telah qathâ€™i. Penelitian ini menggunakan dekriptif analisis dengan pendekatan historis normatif. Hasil Penelitian menunjukkan bahwa Nash dari segi wurud dan tsubut adalah qathâ€™i, karena semua ayatnya sampai kepada kita dengan jalan mutawatir.Namun dari segi penunjukannya menjadi qathâ€™I ad-dalalah dan zanni ad-dalalah. Pembagian ini untuk menjelaskan bahwa ada hal-hal yang sudah terang disebutkan dalam al-Qurâ€™an dan hadis dan ada yang masih perlu diijtihadkan agar dapat diimplementasikan dan diamalkan. Nash qathâ€™i manurut para ulama ushuliun tidak boleh menjadi objek ijtihad karena sudah jelas dan terang disamping juga agar tidak terjadi kekacauan dan terlalu bebas dalam melakukan ijtihad, serta tidak memasukkan hal-hal seperti kewajiban shalat lima waktu, zakat dan hukum-hukum syaraâ€™ lainnya yang telah disepakati menjadi pembahasan ijtihad. Namun diantara ulama ushuliun sendiri masih berbeda dalam menentukan mana yang menjadi dali qathâ€™I dan mana yang menjadi dalil zanni. Persoalan yang menyangkut dengan dalil qathâ€™idan dalil zanni ini, tidak hanya terjadi perbedaan dalam pengkatagorian, akan tetapi adajuga yang membatasi dengan syarat-syarat tertentu, seperti yang dilakukan oleh Asy-Syatibi dan ada yang menolak sama sekali dikotomo qathâ€™i dan zanni,namun mereka tidak cukup kuat dalam mengemukakan alasan-alasan yang dapat kita terima.
Penyebutan â€˜Iwaá¸ dalam Penjatuhan Khuluâ€™: Kontribusi Abu Isá¸¥Äq Al-SyÄ«rÄzÄ«
Authors: Nasaiy Aziz Nasaiy Aziz
Published: November 2018

Salah satu bentuk perceraian yang terjadi dalam rumah tangga atas inisiatif isteri adalah dengan cara khuluâ€™.Ulama beerbeda pendapat tentang kebsahan khuluâ€™ dimaksud. Sebagian mereka berpendapat bahwa bayaran sejumlah uang tebusan (â€™iwaá¸) bukan merupakan salah satu syaraat sah khuluâ€™. Namun sebagian lainnya berpendirian bahwa bayaran sejumlah uang (â€™iwaá¸) dari isteri kepada suami merupakan salah satu syarat sah khuluâ€™ itu sendiri.Ketiadaan bayaran tersebut khuluâ€™ dimaksud belum dianggap sah. Abu Isá¸¥Äq Al-SyÄ«rÄzÄ« berpendapat lain. Menurut beliau khuluâ€™ tersebut baru dianggap sah dan punya akibat hukum bila bayaran sejumlah uang dari isteri kepada suami di samping merupakan salah satu syarat sah khuluâ€™,juga harus disebutkannya ketika suami mengucapkan lafaz khuluâ€™ kepada isteri.Ketentuan seperti ini dimaksudkan untuk membedakan khuluâ€™ dengan talak bjiasa baik talak rajâ€™i maupun talak bain. Penetapan hukum seperti ini dilakukan dengan cara menjadikan hadis sebagai penjelas keumuman ayat Alquran.
Peran Perangkat Desa terhadap Pelaksanaan Perwalian Anak Korban Tsunami (Studi Kasus di Kec. Krueng Sabee, Kab.Aceh Jaya)
Authors: Soraya Devy Soraya Devy , Mela mirdawati Mela mirdawati
Published: November 2018

Musibah tsunami menyisakan luka mendalam bagi masyarakat Aceh. Musibah tsunami Aceh memakan banyak korban, anak-anak telah kehilangan orang tua dan sanak keluarga. Langkah yang harus diambil terhadap anak korban sunami yaitu pengangkatan perawlian anak. Pengangkatan wali anak ini telah dilakukan di berbagai daerah, salah satunya di Kecamatan Krueng Sabee, Kabupaten Aceh Jaya. Tujuan yang ingin digali yaitu terkait peran perangkat desa dalam sistem pengangkatan wali anak korban tsunami di Kec. Krueng sabee berikut dengan pengawasannya, serta pandangan Hukum Islam terhadap pelaksanaan perwalian anak korban tsunami di kec. Krueng sabee. Penelitian ini dilakukan dengan pendekatan studi kasus (case study). Hasil penelitian menunjukkan bahwa peran perangkat desa yaitu melakukan musyawarah pengangkatan wali anak. Prosesnya dilakukan dengan jalan musyawarah gampong, yang melibatkan keuchik, sekdes, tengku imum/imum meunasah, tuha peut gampung, sanak kerabat anak jika masih ada, dan masyarakat gampong secara umum. Perwalian anak korban tsunami di Kecamatan Krueng Sabee Kabupaten Aceh Jaya tidak dilakukan pengawasan. Alasannya: Pertama, penunjukan wali tidak dilakukan dengan akte tertulis. Kedua, anak korban tsunami diwalikan sendiri oleh sanak kerabat yang masih hidup. Ketiga, adanya keinginan masyarakat untuk mengangkat anak, sehingga pengawasan dipandang tidak perlu.
Tinjauan Hukum Islam terhadap Perubahan Talak Tiga Menjadi Talak Satu (Analisis Terhadap Putusan Mahkamah Syarâ€™iyah Banda Aceh Nomor: 0163/Pdt.G/2016/Ms.Bna)
Authors: Muslim Zainuddin Muslim Zainuddin , Syabâ€™ati Asyarah Agustina Syabâ€™ati Asyarah Agustina
Published: November 2018

Artikel ini bertujuan untuk mengetahui bagaimana isi putusan Mahkamah Syarâ€™iyah tentang talak tiga menjadi satu sesuai dengan putusan Mahkamah Syarâ€™iyah nomor 0163/Pdt.G/2016/Ms.Bna, pertimbangan hakim Mahkamah Syarâ€™iyah Banda Aceh dan dalil-dalil hukum dalam menjatuhkan talak, dan tinjauan hukum Islam terhadap putusan Mahkamah Syarâ€™iyah Banda Aceh tentang perubahan talak. Adapun penelitian ini menggunakan metode deskriptif analisis dengan mengumpulkan data melalui penelitian library research (penelitian keperpustakaan) dan field research (penelitian lapangan). Jenis penelitian ini adalah yuridis normatif. Hasil penelitian ini menyimpulkan bahwa isi putusan Nomor 0163/Pdt.G/2016/Ms.Bna yang mana Penggugat telah menjatuhkan talak tiga terhadap istrinya, namun Majelis Hakim memutuskan memberi izin talak rajâ€™i kepada Penggugat terhadap Tergugat, ini sesuai dengan penetapan Undang-Undang Nomor 1 Tahun 1974 tentang Perkawinan, dan Kompilasi Hukum Islam. Adapun pertimbangan hakim menjatuhkan talak tiga menjadi satu dengan berdasarkan Undang-Undang Nomor 7 Tahun 1989 Pasal 65 dan KHI dalam Pasal 118. Dari tinjauan hukum Islam bahwa talak tiga itu tidak jatuh melainkan talak satu dengan berdasarkan hadits Rasulullah saw., di dalam Al-Qurâ€™an juga disebutkan hukum jatuhnya talak tiga, namun tergantung dari niat suami dalam menjatuhkan talak tersebut.
Peran Majelis Sulh dalam Penyelesaian Hak Hadhanah Pasca Perceraian (Studi Kasus di Mahkamah Syariah Kabupaten Tawau, Provinsi Sabah, Negara Malaysia)
Authors: Tarmizi M.Jakfar Tarmizi M.Jakfar , Nur Azizah Fayyadhah Binti Baharuddin Nur Azizah Fayyadhah Binti Baharuddin
Published: November 2018

Pengamalan Sulh di dalam Islam telah berlaku pada zaman awal kedatangan Islam hingga ke zaman para sahabat dan juga para tabiâ€™in lagi yang mana telah memberikan banyak manfaat dan faedah kepada perkembangan masyarakat umat Islam pada masa itu. Artikel ini fokus pada kajian peran majelis sulh dalam penyelesaian hak hadhanah pasca perceraian studi kasus di Mahkamah Syariah Kabupaten Tawau, Provinsi Sabah, Negara Malaysia. Penelitian ini merupakan riset lapangan dengan menggunakan pendekatatan yuridis normatif. Hasil penelitian menunjukkan bahwa Majelis Sulh membantu dan membimbing pihak-pihak berkonflik untuk berbincang, berunding dan mencari persetujuan bersama untuk mencapai penyelesaian, majelis Sulh di Mahkamah Syariâ€™ah ternyata sangat efektif dalam penyelesaian kasus hak hadhanah berdasarkan statistik yang dicatatkan dari tahun 2011 â€“ 2015, majelis Sulh menetapkan tujuh teknik yang wajib diikuti dalam pelaksanaan Sulh, ternyata teknik ini berjaya menyelesaikan kasus yang di daftarkan, masyarakat masih kurang informasi tentang Majelis Sulh. Melalui penyebaran angket dan wawancara, mayarotis masyarakat tidak tahu tentang Majelis Sulh.
Etiological Profile and Neurodevelopment Outcome of Neonatal seizure
Authors: Dongol Singh Srijana , Shrestha Ranendra Prakash Bahadur , Shrestha Asim
Published: November 2018

IntroductionNeonatal seizures are the most common manifestation of neurological disorders in newborn period. It is an important determinant of outcome as well. This study aims to delineate the etiological profile and neurodevelopmental outcome of neonatal seizure. It is also aimed to identify the predictors of neurodevelopmental outcome in survivors.

MethodsWe recruited consecutively 117 neonates with clinically proven seizures admitted in XXXXX hospital, between February 2014 to February 2016. All of them underwent neurological diagnostic testincluding complete blood count, electrolytes, EEG, CSF analysis, neuroimaging depending upon the etiology of seizure in newborn period. After discharge, all infant with neonatal seizure underwent regular neurological examination at least 3 times within first year of life. We tested prognostic value of adverse outcome including developmental delay, post neonatal seizure, vision and hearing impairment.ResultsDuring the study period among total 954 neonates admitted in NICU and neonatal ward, 117 (12.26%) developed clinical seizures. The most common cause of neonatal seizure was hypoxic ischemic encephalopathy 69(59%), followed by infection 20 (17.09%) and metabolic disturbances collectively constituted 16(13.7%). The outcomes were mortality 16(13.7%), post neonatal seizure 18(15.4%), developmental delay 31(26.5%), vision impairment 19(16.2%) and hearing impairment 26 (22.2%).Low Apgar score at 1 minute (p=0.03), low Apgar score at 5 minute (p=0.001), early onset seizure (p<0.001), intractable seizure (p<0.001)and more than one drug used for seizure control (p=0.001) were early prognostic factors for adverse outcome.Key words: hypoxic ischemic encephalopathy, Apgar score, seizure, developmental delay
Experimental investigation of air side pressure loss for wet-cooling tower fills
Authors: Ozgur Arif , Bayrakci Hilmi
Published: November 2018

The pressure loss of air-flow in the cooling tower was measured experimentally with three different type cooling tower fill materials. Air mass flux (3.13 < Ga , < 5.21 kg/m2s), water mass flux (2.43 < Gw , < 5.21 kg/m2s) and height of the fill material (0.6, 0.8, and 1 m) were used as variable parameters for experimental works. Film, curler and splash type fillings were tested in the forced draft counter flow cooling tower unit which has 0.4 ? 0.4 m2 cross-section area. Experimental results were presented graphically. However, these results correlated for each type cooling tower fill material. The pressure loss was increased with increasing air mass flux. The pressure loss of film type filling is 29.1% higher than splash type.
Influence of evaporating rate on two-phase expansion in the piston expander with cyclone separator
Authors: Wu Weifeng , Wang Qi , Zhang Zhao , Wu Zhijun , Yang Xiaotian , Xu Liangcong
Published: November 2018

The trilateral flash cycle shows a greater potentiality in moderate to low grade heat utilization systems due to its potentiality of obtaining high exergy efficiency, compared to the conventional thermodynamic cycles such as the organic Rankine cycles and the Kalina cycle. The main difference between the trilateral flash cycle and the conventional thermodynamic cycles is that the superheated vapor expansion process is replaced by the two-phase expansion process. The two-phase expansion process actually consists of a flashing of the inlet stream into a vapor and a liquid phase. Most simulations assume an equilibrium model with an instantaneous flashing. Yet, the experiments of pool flashing indicate that there is a flash evaporating rate. The mechanism of this process still remains unclear. In this paper, the flash evaporating rate is introduced into the model of the two-phase expansion process in the reciprocating expander with a cyclone separator. As such, the obtained results reveal the influence of evaporating rate on the efficiency of the two-phase expander.
Depression, anxiety and quality of life in patients with melanoma
Authors: Vojvodic Aleksandra , Dedic Gordana
Published: November 2018

Background/Aim. Recent investigations have established a significant correlation between melanoma and quality of life, as well as anxiety and depression in these patients. In prognosis of melanoma, the most important is the stage in which it is diagnosed. The objective of the study was to analyze the quality of life, anxiety and depression in patients with a diagnosis of melanoma at different stages of the disease. Methods. In our cross-sectional study, 40 consecutive patients with melanoma, diagnosed and treated at the Department of Dermatology and Venerology, Military Medical Academy in Belgrade during the period from October to November 2015, were included. Twenty respondents were in stages I and II (localized disease) and 20 respondents in the stage IV (distant metastases). We used European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (EORTC QLQ 30), Beck anxiety inventory (BAI) and Beck depression inventory (BDI). The statistical analysis included parametric and non-parametric descriptive statistics. Results. In patients with stages I and II of the disease, anxiety scores were higher in comparison to those in patients with the stage IV (37.5 vs. 14.5, respectively; p < 0.05), but depression was more pronounced (6 vs. 2.5, respectively; p < 0.05) in patients with the IV stage of the disease. There were statistically significant differences in all segments of quality of life between patients with stages I and II and those with the stage IV of the disease. The global quality of life was significantly worse in patients with the IV stage (33.5 vs. 83), the symptomatology was more pronounced (78.5 vs. 0) and the functioning was significantly worse (31 vs. 85) in relation to patients with stages I and II (p < 0.01) for all segments of quality of life. Conclusion. Anxiety and quality of life decrease, while depression increases with melanoma stages. The need for adequate social and family support as well as psychological assistance in order to achieve better coping with the illness are necessary in patients with melanoma. Further studies are needed for monitoring of anxiety, depression and quality of life from the moment of diagnosis of the disease over time, as well as the impact of new treatment modalities on these parameters.
Sürdürülebilir Turizmin Gelişimine Yönelik Yerel Halkın Tutumlarını İncelemeye İlişkin Bir Araştırma: Akçakoca Destinasyonu
Authors: Dağlı Zülkif
Published: November 2018

Sürdürülebilir
turizm, destinasyonların uzun vadede rekabet avantajı kazanmasında önemli bir
etken olarak ortaya çıkmaktadır. Bu çalışmanın amacı, yerel halkın
sürdürülebilir turizmin gelişimine yönelik tutumlarını belirlemektir. Çalışmada
ayrıca katılımcıların demografik özelliklerine göre sürdürülebilir turizmin
boyutlarına bakış açılarında farklılık olup olmadığı incelenmiştir. Bu kapsamda
önemli bir turizm destinasyonu olan Düzce ili Akçakoca ilçesinde yaşayan
katılımcılar üzerinde bir araştırma gerçekleştirilmiştir. Araştırmada anket
formu aracılığı ile 382 katılımcıdan veriler elde edilmiştir. Elde edilen
veriler kullanılarak yapılan faktör analizi sonucunda, sürdürülebilir turizmin
gelişimine yönelik yerel halkın tutumlarına ilişkin altı boyut tespit
edilmiştir. Bu boyutlar, çevresel sürdürülebilirlik, planlama, halkın turizme
katılımı, ekonomik fayda, algılanan maliyet ve ziyaretçi memnuniyeti şeklinde
kategorize edilmiştir. Öte yandan, katılımcıların demografik özellikleri ile
sürdürülebilir turizmin gelişimine yönelik tutumları arasında anlamlı
farklılıkların olduğu belirlenmiştir.
PHYTOCHEMICAL TEST OF MANGROVE Avicennia alba, Rhizopora apiculata AND Sonneratia alba FROM MUSI RIVER ESTUARY, SOUTH SUMATERA
Authors: Rahmania Nadya , Herpandi Herpandi , Rozirwan Rozirwan
Published: November 2018

Mangrove is one of the plants that has the potential to be developed into medicinal plants. However, further research is needed to prove scientifically the content of secondary metabolites in it. This study aims to identify the secondary metabolites contained from leaves and roots in Avicennia alba, Rhizopora apiculata and Sonneratia alba. The leaves and roots of mangroves extracted by maceration using ethyl acetate. The secondary metabolites contained in mangrove samples obtained by doing phytochemical tests through color tests. Phytochemical test results showed that secondary metabolites contained in mangrove Avicennia alba are flavonoids, steroids/triterpenoids, saponins, and tannins/phenols in leaf samples, whereas in its root samples it contains flavonoids and steroids/triterponoid compounds. Sonneratia alba contains flavonoids, steroids/teriterpenoids, saponins and tannins/phenols in its leaf samples, while the root samples contain flavonoids, steroids/teriterpenoids and tannins/phenols compounds. The leaf samples of mangrove Rhizopora apiculatacontains flavonoid and steroid/triterpenoid compounds whereas in its root samples contains flavonoids, steroids/triterpenoids, saponins as well as tannins/phenols.
Construcciones simbólicas: forma y contenido en el escapulario de la Virgen del Carmen
Authors: Quiroga Nancy
Published: November 2018

El presente artículo de reflexión derivado de investigación presenta los resultados del proyecto “Cultura y estética popular en Boyacá”, en lo correspondiente al estudio de caso de la ciudad de Duitama. El objeto de estudio fue el escapulario, elemento de marcada importancia en la iconografía de la Virgen del Carmen. Los objetivos fueron establecer los condicionantes que lo hacen un proveedor de construcciones simbólicas, y cómo estas constituyen un conjunto de prácticas culturales populares. En primer lugar, se determinan los aspectos históricos y culturales más importantes de la Virgen del Carmen, para abordar posteriormente el análisis estético del escapulario como objeto e imagen y su incidencia en espacios populares. Se realizó un estudio de corte cualitativo que exploró la noción de amuleto desde el imaginario religioso y las prácticas simbólicas proveedoras de significado, en especial para los transportadores. En segundo lugar, se examina el elemento formalmente desde conceptos básicos de diseño, tales como dirección, fuerza y tensión visual, los cuales resultan relevantes en la lectura e interpretación de sus mensajes y códigos de contenidos simbólicos. Por último, tras evaluar los datos resultantes de la aplicación de una encuesta y exponer sus primeros resultados, se pone en evidencia el valor clave del escapulario en la configuración y decoración de los vehículos de los transportadores, como también su incidencia en las construcciones simbólicas propias de las prácticas populares.
Factores psicosociales que intervienen en la regulación de la fecundidad en mujeres, Tunja, Colombia, 2014-2016
Authors: Robles-Santos Ruth Jael , Flórez-Escobar Isabel Cristina
Published: November 2018

Introducción. En Colombia, la regulación de la fecundidad es un derecho, pero es  necesario tener acceso a la información y a los servicios para poder decidir libremente tener hijos o no. Se presentan los factores que intervienen, entre ellos los psicosociales, para el cumplimiento terapéutico de los métodos de regulación de la fecundidad.

Objetivo. Determinar los factores psicosociales en el cumplimiento de los métodos de regulación de la fecundidad y su asociación con variables sociodemográficas.

Materiales y métodos. Se llevó a cabo un estudio descriptivo transversal con enfoque cuantitativo, con una muestra de 318 mujeres y la aplicación de una encuesta.

Resultados. El 61,6 % de las mujeres de la muestra estaba entre los 20 y los 29 años de edad; el 42,3 % obtuvo información de los métodos de regulación de la fecundidad de profesionales de la salud; el 90,0 % siempre los utilizó durante las relaciones sexuales; el 81,4 % tuvo, en promedio, dos hijos; el 19,6 % declaró haber quedado embarazadas utilizándolos; el 91,3 % expresó que es una responsabilidad compartida por la pareja, apoyándolas a seguir las indicaciones del profesional en el 66,0 %; el 56,9 % asistió siempre al control de regulación de la fecundidad. Se encontró asociación entre el nivel educativo de las mujeres y la responsabilidad en el uso de los métodos; el 97,8 % tenía educación superior y consideraba que la responsabilidad es de la pareja, y el 80,1 % de las mujeres con hijos acudía siempre a los controles.

Conclusiones. Los factores psicosociales inciden en el cumplimiento de los métodos de regulación de la fecundidad, dado que un porcentaje significativo refirió como estado conyugal la unión libre, lo que les permitía autonomía para la elección del método y apoyo de la pareja. Las mujeres participaron voluntariamente en el programa y hubo satisfacción con la atención y con la información brindada por el proveedor del servicio.
Prevalencia y factores de riesgo de neumonía asociada a la ventilación mecánica en una unidad de cuidados intensivos adultos, Cúcuta, Colombia
Authors: Rodríguez-Álvarez Leidy , Lamos-Duarte Andrés
Published: November 2018

Objetivo: Determinar la prevalencia y factores de riesgo en el uso de ventilación mecánica que conllevan al desarrollo de neumonía en la unidad de cuidados intensivos adultos en un hospital de tercer nivel de la ciudad de Cúcuta. Métodos: Estudio observacional, analítico de corte transversal con enfoque retrospectivo; los datos fueron obtenidos de historias clínicas de pacientes que ingresaron a la unidad de cuidados intensivos adultos del hospital universitario Erasmo Meoz de Cúcuta, en el periodo comprendido entre 2013 – 2016. Se obtuvo en total 284 historias clínicas. Se analizaron datos de 69 pacientes que cumplieron con los criterios de inclusión establecidos. Resultados: el 42% de la población eran hombres, la presencia de neumonía asociada a la ventilación mecánica tardía, fue del 42% y la ventilación mecánica temprana 15.9%, los gérmenes aislados fueron K. pneumoniae y P. aeruginosa en un 13% de los cultivos reportados. El promedio de días de estancia y ventilación mecánica fue de 29,7(SD 15,6) y 18 (SD 9,9) días respectivamente. El tener una patología inmunosupresora o el ser hombre presenta 3.3 y 3.2 veces respectivamente mayor probabilidad de presentar NAV, lo cual se reflejó con la prueba de chi cuadrado con un valor de p 0.02 Conclusiones:La neumonía asociada a la Ventilación es una entidad que aumenta su tasa de presentación e incidencia, la cual afecta de manera negativa a los pacientes que son candidatos a soporte ventilatorio en el contexto de las unidades de cuidado intensivo, elevando los registros de mortalidad, días de asistencia ventilatoria y permanencia incluso los gastos al sistema de salud.
Percepción de la calidad de la atención en un servicio de urgencias
Authors: Cobo-Mejía Elisa Andrea , Gómez-Martínez Flor Edilia , Rodríguez-Leal María Yohana
Published: November 2018

Introducción. El reconocimiento de la percepción del usuario de la calidad del servicio de urgencias mediante el modelo evaluativo Service Performance, permite la orientación de acciones para mejorar los servicios prestados.

Objetivo. Determinar la percepción de la calidad de la atención del servicio de urgencias de una Empresa Social del Estado en Boyacá.

Método. Se hizo una investigación descriptiva de diseño transversal, con una muestra conformada por 108 usuarios que recibieron atención en el servicio de urgencias durante el segundo semestre del año 2017. Para la recolección de la información, se utilizó la encuesta Service Performance, la cual consta de 22 preguntas organizadas en cinco dimensiones que permiten evaluar la calidad del servicio según la percepción del usuario.

Resultados. La percepción de los usuarios sobre la calidad del servicio de urgencias, en cada una de las cinco dimensiones, obtuvo un puntaje promedio general de 4,09, siendo la dimensión de seguridad la más alta, con un promedio de 4,23, seguida de la empatía, con 4,18, la de capacidad de respuesta, con 4,14, la de fiabilidad, con 4,09 y, la más baja, los elementos tangibles, con 3,79.

Conclusiones. El conocer la percepción de la calidad del servicio de urgencias permite desarrollar acciones, establecer confianza y hacer el seguimiento de la calidad del servicio.
Las TIC en educación superior. Una experiencia de aprendizaje usando Google Sites
Authors: Ahumada Torres Mercedes Elizabeth
Published: November 2018

El trabajo didáctico pedagógico, a nivel universitario, que se realiza usando herramientas y aplicaciones tecnológicas nos llevan a tener conciencia de nuevas formas de generar conocimiento como también a modificar las concepciones del proceso de enseñanza-aprendizaje. Esta metodología exige la implicación activa del alumnado en la construcción de conocimiento de modo individual y colaborativo ya que entran en juego destrezas de tipo intelectual, técnicas y emocionales. La actual sociedad del conocimiento nos invita a cambiar las prácticas universitarias pensando principalemente en la persona que aprende, buscando prepararlo para un mundo en permanente cambio. Son necesarias múltiples competencias como también flexibilidad y disponibilidad a colaborar con otros en un entorno laboral que demanda formación a lo largo de toda la vida. La investigación cualitativa que aquí se expone se ha desarrollado desde una metodología fenomenográfica que consiste en el estudio de significados y comprensiones de las prácticas de aprendizaje alcanzadas con el diseño de un Sites personal por parte de un grupo de estudiantes. Se ha usado la observación participante y entrevistas semiestructuradas para valorar productos y procesos metacognitivos. El grupo ha estado constituído por un total de 25 estudiantes pertenecientes a la Universidad Internacional de Valencia (VIU), que han sido seleccionados de forma intencionada. Los resultados son muy interesantes por la experiencia y calidad de su productividad. Valoran la herramienta como una efectiva oportunidad de aprender haciendo y reconocen su voluntad de aplicarla en otros estudios y futuro laboral con estudiantes de primaria.
Diferencias de sexo en estrategias de aprendizaje de estudiantes online
Authors: Romero Rodrigo Mercedes , San Martín Alonso Ángel , Peirats Chacón José
Published: November 2018

Analizamos aquí las estrategias de aprendizaje empleadas por estudiantes universitarios, de modalidad online, en función del género. En primer lugar, se realiza una exhaustiva revisión de publicaciones que comparten el objeto de estudio, la mayoría de ellas difundidas en la última década y señalando los principales hallazgos de estas investigaciones. El objetivo del estudio es analizar tanto las estrategias empleadas como desvelar semejanzas y diferencias con respecto a modalidades presenciales. Metodológicamente optamos por realizar un diseño multimétodo, en el que el análisis cualitativo tiene como finalidad contribuir a la evaluación e interpretación de los resultados de tipo cuantitativo. Los instrumentos de recogida de información han sido el Cuestionario de Evaluación de las Estrategias de Aprendizaje de los Estudiantes Universitarios (CEVEAPEU), análisis documental de reglamentos, memorias e informes de la universidad, revisión de aulas virtuales, guías didácticas y un seminario asíncrono en el que se les solicitaba a los estudiantes una valoración acerca de sus estrategias de aprendizaje.Entre los resultados obtenidos cabe destacar las semejanzas contrastadas si los resultados son comparados con los apuntados en estudios presenciales, donde las mujeres muestran un perfil estratégico más sólido en comparación con sus compañeros. Esto es, planifican y aprovechan más el tiempo de estudio, presentan una motivación intrínseca por el aprendizaje, tienen una marcada preferencia por realizar trabajos y estudiar con otros compañeros, comentar dudas y pedir ayuda tanto a sus iguales como al profesorado. Sin embargo, en la estrategia de control de la ansiedad las mujeres obtuvieron peor resultado.
Impacto del uso de los recursos tecnológicos en el rendimiento académico
Authors: Martínez-Garrido Cynthia
Published: November 2018

El uso de los recursos educativos en las lecciones ha sido destacado por la investigación sobre Enseñanza Eficaz como uno de los factores claves que hacen que la docencia sea de calidad. La presente investigación busca describir la utilización que los estudiantes de Educación Secundaria dan a los recursos tecnológicos dentro y fuera de la escuela y determinar la relación entre la utilización de los recursos tecnológicos dentro de la escuela y el rendimiento académico de los estudiantes en Matemáticas y Lectura. Para dar respuesta a este objetivo se lleva a cabo una explotación secundaria de la base de datos PISA 2015 con los datos de 6.736 estudiantes de 201 escuelas de Educación Secundaria Obligatoria en España. Como método de análisis de datos se utilizan los análisis multinivel. Los resultados señalan que los recursos tecnológicos están presentes en el día a día de los estudiantes tanto fuera como dentro de las escuelas y que la utilización del email, la conexión a internet y el uso del ordenador generan mejoras en el desarrollo académico de los estudiantes en Matemáticas y Lectura. El compromiso con una enseñanza de calidad está ligado al uso de los recursos tecnológicos, por ello, es fundamental que su utilización ajustada al contexto y estudiantes en todas las escuelas.
Medical exchange project for students and young doctors between Japan and Russia
Authors: Yamakawa S. , Razvina O. , Ito M. , Hibino H. , Someya T. , Ushiki T.
Published: November 2018

For more than 25 years Niigata University School of Medicine has been organizing medical exchanges with universities of the Russian Far East and Siberia. This exchange has turned out to be mutually beneficial for both universities, giving motivation to medical students and young doctors to strive for knowledge of international medicine. “Program for priority placement of foreign students sponsored by Japanese government” and “Re-inventing Japan project” initiated by Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT) were adopted in 2014, so it gave us a perfect opportunity to expand the existing program. In 2017, the MEXT approved the application of Niigata University together with Hokkaido University for «Program of Globalization in the field of university education (in cooperation with Russia), the creation of a platform for interaction”. We hope advances in the field of medicine and medical care achieved as a result of such unique cooperation between Japan and Russia will greatly contribute not only to the welfare of citizens of both countries, but also to the development of industry and economy. We would like to share experience gained by our university in the sphere of Japanese-Russian medical exchanges and educational programs, as well to describe the prospects for further development.
A new nonsurgical experimental model for Asherman syndrome created in rats
Authors: BÜYÜK Başak
Published: November 2018

Aim: Asherman Syndrome (AS) is a partial or complete obstruction
of the uterine cavity with adhesions as a result of trauma. In pre-clinical
studies, to be able to show the effectiveness of new treatment methods, first
of all, the AS model needs to be created in the animals. The aim of this study
is to develop a new and effective nonsurgical method for using in AS and intrauterine
adhesions modeling, and through this way, to propose a more effective method
for researchers in terms of safety and feasibility. Methods: Twelve
female Wistar Albino rats were divided into two groups. It was reached to the left uterine horn transvaginally
by using pre-prepared pink color (20 gauge) cannula. While 0.2 ml normal saline
was applied to the animals in Group I (control group), 0.2 ml (Trichloroacetic
acid) TCA was applied to the animals in Group II (experiment group).The right
uterine horns of the animals were left without treatment. After three menstrual
cycles, the animals were sacrificed and Hematoxylin-Eosin and Masson’s Trichrom
staining were performed and evaluated histopathologically. Inflammation was
evaluated in Hematoxylin-Eosin staining and fibrosis was evaluated in Masson’s
Trichrom staining.Results: Whereas the
uterine sections of the Group I have normal histologic appearance, inflammation
and fibrosis were found in the left uterine sections of the Group 2 by
histopathological evaluation. Results were statistically significant (p=0.002).

Conclusion: The
proposed nonsurgical AS modeling method created disease, and this was also
revealed by histopathological examinations. Through this way, a new AS model is suggested
without surgery, in which the disease is correctly created.
Renoprotective potential of quercetin in experimental diabetic nephropathy: assesing antiapoptotic and antioxidant effects
Authors: TUNÇDEMİR Matem , BÜYÜKÇOLPAN MİRZATAŞ Eda , UZUN Hafize
Published: November 2018

Aim: We investigated renoprotective
and anti-apoptotic effects of quercetin, a potent bioflavonoid, by evaluating expression
of apoptosis-regulatory genes that contribute to the kidney damage caused by
diabetes in rats.

Methods: Rats were divided
into 4 groups; Control, STZ-induced diabetic, STZ-induced diabetic+Quercetin
and Quercetin control. Values of fasting blood glucose, body weight and urine
microalbuminuria measured. Immunohistochemistry was performed using bax, bcl-2,
caspase-3 antibodies. For apoptosis detection, TUNEL method was applied.
Advanced oxidation protein products (AOPP), protein carbonyl oxidation (PCO),
malondialdehyde (MDA) and superoxide dismutase (SOD) activity were measured in
homogenized kidney tissues.

Results: Blood glucose and
microalbuminuria levels were significantly decreased in quercetin-treated
diabetic group compared to the untreated-diabetic group (p=0.020 and p=0.003; respectively).  MDA, AOPP and PCO levels were significantly
decreased (p=0.001, p=0.0001 and p=0.0005; respectively); however, SOD activity
were found to increase in quercetin-treated diabetic group (p=0.005).
Immunostaining of bcl-2, bax and caspase-3 was decreased compared to the
untreated-diabetic group. Apoptotic cells especially increased in the kidney
tubuli of untreated-diabetic group and on the contrary, a significant decrease
was observed in the group that received a quercetin treatment (p=0.0001).

Conclusion:
Our results revealed that antiapoptotic effects of quercetin, which has predominantly
antioxidant effects, may be useful in reducing effects of diabetic
complications and preventing new complications.