bluuebunny/crossref_metadata_2025 huggingface dataset:
Successful Embolization in Recurrent Hemoptysis Caused by Pulmonary Aspergilloma: A Case Report
Authors: Yaman Muli , Sugiri Jane , Putra Ngakan , Santosaningsih Dewi , Aslam Achmad
Published: March 2023

Background: Aspergilloma is a fungal infection that can cause recurrent hemoptysis. One of the treatment modalities is embolization, which has a success rate of 85% to 100%, although the recurrence rate may reach 10% to 33%.

Case Illustration: A 29-year-old female came to the emergency ward with recurrent hemoptysis. She had a history of tuberculosis with completed treatment 7 years ago. Chest radiography showed left lung tuberculosis with emphysematous lung. Chest CT with contrast revealed an air-crescent sign, and culture from bronchoalveolar lavage (BAL) showed Aspergillus spp. Then, she was diagnosed with pulmonary aspergilloma. Embolization was performed in the left internal mammary artery, and the blushing was decreased by 80%. However, the hemoptysis was still recurrent; a second embolization was performed in the left supreme intercostal artery, costocervical trunk artery, and bronchial artery, resulting in no blushing. The patient had no further episodes of hemoptysis, and her antifungal therapy was changed from fluconazole to voriconazole.

Discussion: Recurrent hemoptysis can be caused by pulmonary aspergilloma. Embolization is usually done to reduce bleeding before surgery. The patient had performed embolization 2 times with no further episodes of hemoptysis. Surgical resection as a definitive treatment was recommended in this case, but the patient refused. Therefore, the patient’s management was optimized using voriconazole and embolization for the hemoptysis.

Conclusion:  Management of recurrent hemoptysis in patients with aspergilloma may include embolization and antifungal treatment which give improved clinical outcomes.

Keywords:  recurrent hemoptysis, embolization, aspergilloma, tuberculosis
Severe Abdominal Pain Due To Gastrointestinal Obstruction in Patient With Lung Adenosquamous Metastases in Colon
Authors: Zata Dini  , Pratiwi Suryanti , Setyawan Ungky , Budianto Aries , Yudhanto Hendy , Erawati Dini
Published: March 2023

Background: Lung cancer is the most common cause of cancer-related death globally. Moreover, metastatic cancer from the lungs frequently occurs and is commonly identified at the first diagnosis. The primary cancer must be identified in order to establish the most effective treatment. However, colonic metastases are rare with incidence of 0,1%.

Aim: This report describes an unusual case of colonic metastases from lung adenocarcinoma.

Methods: Patient (58-year-old male) was examined with Fiber Optic Bronchoscopy and core biopsy in the lungs, and the results were suspicious for squamous cells. The patient had severe abdominal pain and bloating for 1 week and had signs of gastrointestinal obstruction in his second visit. The result of urgent laparotomy was adenosquamous and the result of immunohistochemical examination was negative P40 and positive Napsin A in both lungs and colon.

Results: The lung biopsy result indicated squamous cell and the ceccum showed adenosquamous. The immunohistochemical examination using P40 and Napsin A of both lung and ceccum specimens indicated that the lung was the primary source of metastases to the colon.

Conclusion: The patient suffered from a squamous cell lung tumor and reported severe abdominal pain due to metastases to the colon with adenosquamous results.
Analysis of the COVID-19 prevalence among children in Ukraine during the first year of the pandemic
Authors: Antypkin Yu.G. , Lapshyn V.F. , Umanets T.R. , Kaminska T.M. , Banadyha N.V. , Koloskova О.К. , Lychkovska O.L. , Harashchenko T.A. , Podolskiy Vl.V. , Podolskiy V.V.
Published: March 2023

Background. Studying COVID-19 prevalence among children is important for constant monitoring of the epidemiological situation, determination of the most vulnerable categories of children, and planning preventive measures. The aim of our research was a retrospective study of COVID-19 prevalence among children of Ukraine in 2020. Materials and methods. A retrospective study of COVID-19 prevalence among children from different regions of Ukraine was conducted, based on official statistical reports of the Ministry of Health of Ukraine. The prevalence of COVID-19 was measured as the number of cases per 100,000 children. Results. Among the population of Ukraine, children with confirmed SARS-CoV-2 infection amounted to 0.12 %, and among the children’s population of Ukraine — 0.7 %, while the prevalence rate reached 688.64. The incidence of COVID-19 among children in 2020 was highest in Kyiv, Chernivtsi, and Zaporizhzhia regions, and the lowest one was recorded in Kirovohrad, Luhansk, and Donetsk regions. In the age structure of Ukrainian children with SARS-CoV-2 infection, adolescents (63.8 %) prevailed. Conclusions. Adolescents were the age group of children most vulnerable to SARS-CoV-2 in Ukraine. The relatively low COVID-19 prevalence among children in Ukraine may be evidence of underdiagnosis due to insufficient coverage of laboratory testing for SARS-CoV-2 infection in the first year of the pandemic.
Levels of antibodies to adalimumab in children with juvenile idiopathic arthritis at different stages of treatment
Authors: Marushko T.V. , Onufreiv O.Ye. , Marushko Yu.V. , German O.B.
Published: March 2023

Background. Juvenile idiopathic arthritis (JIA) is one of the most common rheumatological diseases of childhood. The central place in the problem of JIA belongs to the question of treatment the timeliness and adequacy of which determine the disease prognosis and, in fact, the entire future of the child. Immunobiological therapy can cause stable clinical and laboratory remission, as well as stop the further progression of structural changes, affecting the pathogenetic link of idiopathic arthritis. But the lack of response to therapy or a decrease in its effectiveness remains a fairly common problem and, in many cases, can be caused by the immunogenicity of immunobiological drugs, especially in case of treatment with tumor necrosis factor inhibitors. Aim of the work: to study the level of antibodies to adalimumab in children with juvenile idiopathic arthritis at different stages of treatment for analysis of immunogenicity. Materials and methods. The concentration of antibodies to adalimumab in 80 serum samples from patients with JIA was studied and evaluated, treatment effectiveness and adverse events were analyzed in 56 patients with JIA at different stages of therapy. Two groups were identified. The first one included 24 patients who had at least a 6-month break in adalimumab administration for non-medical reasons during which treatment was continued with methotrexate with periodic intra-articular injection of glucocorticoids. The level of antibodies to adalimumab was evaluated before the break and 1 month after the reinitiation of adalimumab administration. The second group consisted of 32 children who continued adalimumab without a break during treatment. Disease activity was measured using JADAS-27. Antibodies to adalimumab were detected by enzyme-linked immunosorbent assay. Results. During the examination, an elevated level of antibodies to adalimumab was detected in 10 of 24 serum samples (42 %) before non-medical withdrawal in group I. Among the results of group II, elevated levels of antibodies to adalimumab were found in 12 samples, which was 38 %. The correlation analysis revealed direct statistically significant relationships of moderate strength between the level of antibodies to adalimumab and the indicator of inflammatory activity on JADAS-27 (Spearman’s r = 0.39, p < 0.05), as well as between the level of antibodies and disease duration (Spearman’s r = 0.32, p < 0.05). Conclusions. Monitoring serum antibodies to adalimumab is informative for the correct interpretation of treatment effectiveness and the course of the disease with immunobiological treatment, as it may improve understanding of the clinical consequences of continued therapy, help prevent adalimumab immunogenicity, develop follow-up strategies and, as a result, can affect a long-term outcome of treatment for JIA.
Quality of life indicators in children with non-traumatic and non-syncopal transient loss of consciousness and their families
Authors: Kovalchuk T.A. , Boyarchuk O.R.
Published: March 2023

Background. There are extremely limited research on the quality of life in children with non-traumatic and non-syncopal transient loss of consciousness (TLOC), which does not sufficiently reflect the impact of epilepsy, first unprovoked epileptic seizure or psychogenic TLOC on the parental quality of life and family functioning. The purpose was to provide a comparative analysis of quality of life in children with non-traumatic and non-syncopal TLOC, as well as to study the impact of these diseases on the family quality of life. Materials and methods. Twenty-two patients with epilepsy, 18 with first unprovoked epileptic seizure, and 18 with psychogenic TLOC aged 8–17 years were examined. The control group consisted of 40 apparently healthy children. Quality of life in children and their parents was assessed using the PedsQL™ 4.0 Generic Core Scales (child report, adolescent report, parent report), and the PedsQL™ 2.0 Family Impact Module (parent report). Results. Epilepsy and psychogenic TLOC have a negative impact on the quality of life of children. Epilepsy was accompanied by deterioration of physical (57.1 ± 5.2; 77.3 ± 4.8 points) and psychosocial health (60.7 ± 5.7; 76.3 ± 2.7 points), while psychogenic TLOC were characterized by only low physical health (55.0 ± 5.5; 77.3 ± 4.8 points) according to patient self-reports (p < 0.01). The quality of life of children with epilepsy was influenced by age (r = –0.55; r = 0.007) and features of clinical manifestation of the epileptic seizure (r = –0.56; r = 0.007). The number of previous non-epileptic seizures had an impact on quality of life among patients with psychogenic TLOC (r = –0.60; r = 0.0008). The first unprovoked epileptic seizure was not accompanied by quality of life deterioration among children and parents. Only epilepsy was associated with a decrease in the quality of life of parents and family as a whole, mainly due to an increased anxiety (38.8 ± 4.5; 63.2 ± 4.0 points), a decrease in emotional functioning (47.5 ± 3.9; 66.9 ± 3.3 points), a lack of effective communication between family members (50.0 ± 4.8; 79.4 ± 2.9 points); p < 0.01. Conclusions. The combined evaluation of quality of life in children and their parents helps better understand the impact of disease course peculiarities and treatment on the child’s and his family’s quality of life in order to provide timely medical and psychological assistance.
Комплексна оцінка деяких параметрів фагоцитозу у дітей віком 2–5 років залежно від частоти захворюваності на гострі респіраторні інфекції
Authors: Tymoshyna O.V. , Ovcharenko L.S. , Vertehel A.O. , Samokhin I.V. , Kryazhev O.V.
Published: March 2023

Актуальність. Після зараження респіраторними вірусами спостерігається підвищена продукція прозапальних цитокінів, включно з фактором некрозу пухлини α (ФНП-α), інтерлейкіном (IL) 6, IL-1β, які призводять до перехресної активації нейроендокринної імунної системи, що здатно погіршувати фагоцитоз з підвищенням захворюваності на гострі респіраторні захворювання (ГРЗ), формуючи порочне коло. Мета дослідження: підвищення ефективності діагностики імунних порушень при частих ГРЗ у дітей віком 2–5 років шляхом порівняльного аналізу даних, отриманих на підставі дослідження деяких параметрів фагоцитозу, сироваткових рівнів прозапальних цитокінів та продуктів перекисного окиснення ліпідів (ПОЛ). Матеріали та методи. Під спостереженням перебували 60 дітей віком від 2 до 5 років, з яких було сформовано 2 групи: 1) діти, які часто хворіють на гострі інфекційні захворювання респіраторного тракту (n = 30); 2) діти, які хворіють на гострі інфекційні захворювання респіраторного тракту менше ніж 6 разів на рік (n = 30). Результати. Серед дітей 1-ї групи була збільшена частота реєстрації низьких показників фагоцитарного числа (на 60,0 %, р < 0,05), фагоцитарного індексу (на 56,0 %, р < 0,05), індексу завершеності фагоцитозу (на 70,0 %, р < 0,05), стимульованого стафілококом НСТ-тесту (на 50,0 %, р < 0,05) та високих показників спонтанного НСТ-тесту (на 43,3 %, р < 0,05), вмісту у сироватці крові інтерлейкіну-1β (на 46,7 %, р < 0,05), інтерлейкіну-6 (на 43,3 %, р < 0,05), інтерлейкіну-10 (на 30,0 %, р < 0,05), ФНП-α (на 46,7 %, р < 0,05); відзначалося збільшення співвідношення інтерлейкіну-6/-10 в 2 та більше рази, високих показників гідроперекисів ліпідів (на 80,0 %, р < 0,05), дієнових кон’югат (на 80,0 %, р < 0,05), малонового діальдегіду (на 76,7 %, р < 0,05), дієнових кетонів (на 76,7 %, р < 0,05), шифових основ (на 76,7 %, р < 0,05). Висновки. Діти віком 2–5 років, які часто хворіють на ГРЗ, мають особливості поглинальної, цитокініндукуючої й метаболічної функцій фагоцитозу, що проявилося у збільшенні сироваткової концентрації прозапальних цитокінів та продуктів усіх стадій перекисного окиснення ліпідів клітинних мембран.
Trait anxiety and somatization levels in children with irritable bowel syndrome
Authors: Semen M.O. , Lychkovska O.L.
Published: March 2023

Background. According to the biopsychosocial model of medicine, irritable bowel syndrome (IBS) is a heterogeneous disorder that occurs as a result of the complex interaction of biological, psychoemotional and psychosocial factors. Their combination is individual for each patient. The study aims to evaluate the psychoemotional features (anxiety and somatization) in children with IBS depending on the predominant bowel habit and the trigger factor in the development of the disorder. Materials and methods. We enrolled 55 children aged 6–12 years with a verified diagnosis of IBS, following Rome IV Criteria. The control group included 45 children of the same age and gender. The levels of anxiety and somatization were assessed by the Children’s Manifest Anxiety Scale and the Somatoform Symptom Screening, respectively. Results. Children with IBS had significantly higher level of anxiety (р < 0.0001) and somatization (р < 0.0001) in comparison to the control group. We have not found any significant differences in these parameters according to the predominant bowel habit. However, the analysis based on the nature of the trigger factor in the onset of the disorder revealed remarkably higher levels of anxiety (р = 0.0006) and somatization (р = 0.05) in children with stress-associated IBS. Moreover, a direct correlation between the studied parameters (r = 0.69, p < 0.0001) proves their close connection and a tendency to augment each other. Conclusions. Our study confirms a heterogeneity of IBS in children. As psychoemotional factors play a crucial role in the occurrence of IBS, it is necessary to consider them in the development of personalized care planning.
The Dilemma Facing the Immunity System for Civil Acts of Courage and the Countermeasures to Solve It
Authors: Yingdong Dai
Published: March 2023

In today’s society, there is less and less care and help among the public, and many negative cases of righteousness and courage are spread in the social media, leading the public to question the act of righteousness and courage, such as the “Zhao Yu case”, etc. Many righteous people help others with good intentions, but their legitimate rights and interests are not protected, resulting in the phenomenon of “the righteous and brave both bleed and shed tears” is extremely detrimental to the construction of socialist rule of law. In order to solve this problem, the Civil Code proposed a civil immunity system for courageous acts of righteousness, but in the implementation process is faced with unclear subjects, unclear responsibilities, operational problems, etc., need to be optimized and improved by clarifying the responsibilities of different subjects, standardizing the way of defining negligence, and reducing the obligation of proof for the courageous.
EMUSIC USING SUPPORT VECTOR MACHINE LEARNING ALGORITHM
Authors: G DHANALAKSHMI , S KAVYA , P DARRSHINI , CAROLIN J TEENA
Published: March 2023

The emotion or mood of a user can be detected by their facial expressions. Those expressions can be extracted from the live feed through the system’s camera. Machine learning provides various techniques, one of which is detection of facial expression. It connects us across markets, aeons, backgrounds, dialects, political views, and financial status. Nowadays, music applications and other streaming services are of high demand and are sought by many people not restricted to ages as there are a remarkable and rapid evolution of multimedia, digital music, and cellular networks. Most of the people use music for their mood regulation, increase energy level, and more specifically to change their unpleasant mood or reduce tension. In addition to it, by tuning in to the right type of music at the apparent time may refine your mental health. Thus, human emotions or mood have a intense bond with music. Here, in this project, we propose an efficient solution to meet the people needs in music by live feed and Support Vector Machine learning algorithms.
DESIGN AND IMPLEMENTATION OF A SMART HOME AUTOMATION SYSTEM
Authors: OLUWAFEMI ILESANMI BANJO , BELLO OLUWASEYI OLAWALE , OBASANYA TAYO DORCAS
Published: March 2023

Objective: Due to the rapid development of various technologies and communication devices, the use of the Internet of Things (IoT) for automation has become increasingly common in non-industrial environments. It has integrated well into our day-to-day activities, leading us toward the use of smart home technology. Smart home systems are intelligent system that provide control to home appliances and also security systems. There are limited numbers of intelligent systems that address multiple aspects of the home automation, such as appliances control, security bridge detection, and reducing energy consumption and cost simultaneously. Hence, this research developed a system that solves these problems with an intelligent home automation system.
Methods: The designed system was based on Arduino ATMEGA328P microcontroller, MQ2 sensor for gas detection, passive infrared (IR) sensor for motion detection, and flame sensor to detect fire outbreak. Arduino ATMEGA328P was used as a central controlling unit that controls the flow of system operations to achieved smart home automation system.
Results: The system sends audible alarms through a buzzer to draw the user’s immediate attention. It also sends a warning message to the user’s mobile phone through the global system for mobile communication module.
Conclusion: The system achieved a precision rate of 94.44% and provided a cost-effective platform for interconnecting a variety of devices and various sensors in a home through the IoT.
INTEGRAL TRANSFORM AND FRACTIONAL KINETIC EQUATION
Authors: PATHAK AARTI , RAJSHREEMISHRA2, RAJSHREEMISHRA , JAIN D.K. , AHMAD FAROOQ , AHMAD PEER JAVAID
Published: March 2023

With the help of the Laplace and Fourier transforms, we arrive at the fractional kinetic equation's solution in this paper. Their respective solutions are given in terms of the Fox's H-function and the Mittag-Leffler function, which are also known as the generalisations and the Saigo-Maeda operator-based solution of the generalised fractional kinetic equation. The paper's findings have applications in a variety of engineering, astronomy, and physical scientific fields.
IN VITRO ANTIFUNGAL ACTIVITY OF THYME OIL AGAINST CANDIDA ALBICANS ISOLATED FROM NAIL FUNGUS (ONYCHOMYCOSIS)
Authors: ALAHMAD AYA , BERAKDAR NOURA , RADWAN ABDULKARIM , ALYOUSEF ESRAA
Published: March 2023

Objectives: The aim of this study is to investigate the antifungal activity of thyme oil against Candida albicans of nail fungus (onychomycosis) from patients in Syria.
Methods: An in vitro study was carried out using the following C. albicans strains involved in onychomycosis using well diffusion (WD) testing: C. albicans (ATCC 90028) and 15 strains were compiled from Aleppo Hospital. The antifungal activity of thyme oil was determined in the form of inhibition zone using antifungal assay agar WD testing. In all experiments, the obtained results indicated that thyme oil has inhibitory effects on C. albicans (ATCC 90028) and some 15 strains.
Results: This study showed that thyme oil was active against the tested C. albicans strains. Thyme oil was more effective against C. albicans compared to terbinafine. thyme oil may have potential for use in the development of clinically useful antifungal preparations.
Conclusion: Thyme oil might be highly effective in the natural prevention treatment of onychomycosis.
DRUG REPURPOSING OF COMMERCIALLY AVAILABLE AZOLES AGAINST ASPERGILLOSIS PEROXIREDOXIN ASP F3 ALLERGEN DRUGS
Authors: S SREERAJ , K PRANAV
Published: March 2023

Objectives: Aspergillus peroxiredoxin is a significant contributor to a multitude of infections in both humans and animals infecting the respiratory system due to which lungs related illnesses and fatalities continue around the globe. This research examines various antifungal drugs which are effective against aspergillus.
Methods: The present study implements computational methods to assess the effectiveness of several phytochemicals toward the A. peroxiredoxin protein PyRx, the virtual screening tool was used to systematically perform molecular docking. It was done so to test the binding affinity with A. peroxiredoxin protein 5J9B, 10 phytocompounds were selected from Azole Antifungals which was based on previous knowledge. Using ADMET filters, the pharmacological evaluation of the ligands was performed.
Results: The ligands flutrimazole, clotrimazole, fluconazole, sertaconazole, and bifonazole demonstrated the best binding with the target protein peroxiredoxin Asp f3.
Conclusion: The broad-spectrum anti-fungal drug Flutrimazole demonstrated the least binding and best pharmacological parameters with the target proteins. This drug can be repurposed for other fungal infections.
EXPLORING THE PHARMACOLOGICAL MECHANISM OF NARINGENIN AND ITS DERIVATIVES AGAINST RHEUMATOID ARTHRITIS USING NETWORK PHARMACOLOGY AND MOLECULAR DOCKING TECHNIQUES
Authors: MONTEIRO VINITHA JANICE
Published: March 2023

Objective: Flavonoids like Naringenin (NR), which have potent anti-inflammatory effects, are crucial in the treatment of rheumatoid arthritis (RA). Using network pharmacology and molecular docking, this study investigates the potential pharmacological mechanism of NR and its derivatives in the treatment of RA.
Methods: The current study’s purpose was to employ computational methodologies to evaluate the efficiency of several NR phytochemicals against RA. The Indian medicinal plants, Phytochemistry and therapeutics and DrugBank database is used to retrieve potential ligands. While, known target proteins associated with RA were retrieved through the GeneCards database and predicted target proteins related to NR were screened through the STITCH database. STRING database was used to construct a protein-protein interaction network. Gene ontology and Kyoto Encyclopaedia of Genes and Genomes pathway enrichment involved in targets were performed by the ShinyGo 0.76.3 database. The BIOVIA Discovery Studio Visualizer and the virtual screening tool PyRx were used to systematically perform molecular docking. To assess their compatibility with the RA, the top 6 phytocompounds from NR were selected. The pharmacological evaluation of the ligands was carried out using ADMET filters.
Results: The phytocompounds 4’-Hydroxyflavanone and Sakuranetin from the NR derivatives were discovered to be the most potent antagonistic for the protein tumor protein P53 and interleukin-10 protein.
Conclusion: Ligands 4’-Hydroxyflavanone and Sakuranetin are deserving candidates for the suppression of inflammation of RA due to their strong affinity for the protein.
NEUROPROTECTIVE ACTIVITIES AND REPAIR MECHANISMS OF GINKGO BILOBA EXTRACT EGB 761 ON CNS INJURIES AND NEURODEGENERATIVE DISORDERS
Authors: JADHAV RACHNA SHASHIKANT , PATIL NIRANJAN NANDKUMAR , SAHA BHASKAR
Published: March 2023

With an increasing number of neurodegenerative diseases and brain injuries, the focus of the research using synthetic and herbal medicines with an objective to treat the existing problems in neuroscience is ever-increasing. The availability of natural resources, knowledge about ancient herbs, and the mechanisms underlying neurodegenerative disorders and brain injuries is essential to developing herbal supplements with the potential to treat brain diseases and injuries. Despite the variety of synthetically manufactured drugs for brain health, the need for herbal and natural supplements is ever-rising due to the adverse long-term side effects of synthetic drugs. Ginkgo biloba — an Asian plant that is known to possess various neuroprotective properties — has been used as a medicine, even before 1505 AD. G. biloba extract EGB761 has been known to treat and manage impaired nervous system disorders. The current review discusses the neuroprotective properties of G. biloba and its repair mechanisms against subarachnoid hemorrhage, central nervous system (CNS) injuries like traumatic brain injury, ischemic brain injury, early brain injury, spinal cord injury, hypoxia, neuronal apoptosis, neurodegenerative diseases like Alzheimer’s, Parkinson’s, neuroplasticity, neurogenesis, synaptogenesis and its free radical scavenging activity, and neuroleptic properties for a nutritional approach to manage neurodegenerative disorders and CNS injuries.
A GEOSPATIAL APPROACH ON EXAMINING THE INTERACTION BETWEEN SHIFTING WEATHER AND MENTAL HEALTH OF CONSTRUCTION WORKERS AT SPECIFIC SITES OF CHENNAI CITY
Authors: R JAGANATHAN , A SONA , R V SHURMILI
Published: March 2023

Objectives: Urbanization is one of the most important global developments of the 21st century, and it has a substantial impact on health. Because of immigration, urbanization may generate challenges such as stressful events, a poor social network, and excessive city growth. Along with these circumstances, shifting weather conditions can have a negative impact on mental health, making it a critical procedure that must not be underestimated.
Methods: This study uses geospatial technology to access the relationship between shifting weather and the mental health of construction workers in different construction sites of Chennai city zones. The data sets used for this cross-sectional study will be temperature data for two different months, that is, the hottest month (June) and the rainy month (July) along with the mental health data. This data set used here helps to evaluate the difference in workers’ mental health in higher temperature month and low-temperature month.
Results: The main finding shows that even minor fluctuations in the average temperature have resulted in a significant rise in mental distress and cases of severe heat-related illness. Based on the variation in temperature, the works have mentally changed the way of overviewing the works. The outcome explains that exposure to sun throughout working hours has increased mental distress.
Conclusion: With regard to the result, we can conclude that higher temperatures are associated with an increase in mental illness including self-reported instances of poor mental health. Cold temperatures diminish negative mental health effects, whereas hot temperatures aggravate them. The findings imply that temperature has a considerably different effect on mental health than it does on physical health and that it has a relatively similar effect on other behavioral and psychological consequences.
HOW POSITIVE IS POSITIVE PSYCHOTHERAPY? (EXAMINATION OF POSITIVE PSYCHOTHERAPY)
Authors: ÖZEN YENER , TÜRKMEN İREM
Published: March 2023

The aim of this study is to discuss positive psychotherapy in general terms and concepts. Positive psychotherapy is an important psychotherapy approach founded in 1968 by Nossrat Peseschkian. Since the 1990s, it has become more known. It is a combination of psychodynamic, existential, cultural, and behavioral theories. The word positive here means the actual, the real. The psychotherapist helps the client to see and understand the problem by making the current symptom more understandable. Positive psychotherapy also has a positive view of people. He argues that people are inherently good and should focus on the good aspects they have. It has three main principles: Hope, balance, and counseling. Positive psychotherapy is based on the balance model. By interpreting the symptoms positively, it is aimed for the client to approach the balance. It tries to explain the symptoms with its primary and secondary abilities. It aims to strengthen the positive resources of individuals to cope with the conflicts they experience, to continue their lives in a better quality and to realize themselves.
A LOOK AT JUSTICE CONDITIONS ON DIFFERENT IRANIAN ETHNICS IN ISLAMIC REPUBLIC OF IRAN’S CONSTITUTION (BASED ON DISTRIBUTIVE JUSTICE)
Authors: KHALAF MASOUD EMADI , ABBAS ALI POUR
Published: March 2023

Iran is a multiethnic country including various ethnic, linguistic, and religious groups. Persians, Azeris, Turkomans, Kurds, Lors, Baluchis, and Arabs as the well-known ethnics of Iran are scattered throughout geography of Iran. Constitution as a supreme law with a main purpose of providing justice illustrates distributive justice in different articles including the articles 15, 19, 20, 28, 29, 30, 31, and 43 and regards all the Iranians equal share for possession of economic and social rights. Distributive justice esteemed as social-economic justice is a concept whose background refers to the old history and in a modern concept; it seeks the government guarantee for distribution of country’s wealth throughout the whole community in a manner that all the citizens hold a certain value of worldly facilities concerning their rights. The current descriptive-analytic study having been performed in the context of library research is performable in terms of purpose, because it’s findings could be effective in the decision and policy making. This research seeks to answer the significant question that whether the distributive justice of Iran’s ethnics is of any importance to the constitution of Islamic Republic of Iran or not. According to the results of this work, despite the stipulation of equality principle by constitution, distributive justice of Iran’s ethnics is not performed except for some cases. Besides, the constitution lacks the required explicitness and includes some ambiguities.
Metabolic engineering of Saccharomyces cerevisiae for ethanol and butanol biofuel production
Authors: Khan Salman , Hussain Asif , Hussain Muhammad Iftikhar , Aqeel Sahibzada Muhammad , Basharat Samra , Hussain Arif , Al-Ansi Waleed , Abdulqader Abdulqader , Yao Nie
Published: March 2023

The production of biofuels through biological processes has garnered increasing attention due to their potential benefits over conventional fuels, including lower greenhouse gas emissions, higher energy output, and reduced-price fluctuations. However, the metabolic processes of primitive microorganisms used in biofuel production are not compatible with those of fossil fuels. To address this, scholars have employed metabolic engineering techniques to modify the metabolisms of various microorganisms, including S. cerevisiae, for enhanced biofuel production. Specifically, overexpression of enzymes involved in bioethanol and biobutanol production, knockouts of competing pathways, improvements in carbon flux and tolerance have been applied to maximize the potential of S. cerevisiae for bioethanol and biobutanol production. This review focuses on the current state of metabolic engineering of S. cerevisiae for the production of bioethanol from lignocellulose and biobutanol from all kind of substrates, along with the potential use of cell surface technology in this field.
Physicochemical, colorimetric properties and yield of bresaola from beef, Baladi-goat and Awassi-sheep in Lebanon
Authors: Abi-Salloum Bachir , Al-Nahum Maguy , Rached Mohammed , Dimassi Ossama
Published: March 2023

Yield, physicochemical and colorimetric characteristics of bresaola from Lebanese Baladi-goat and Awassi-sheep compared to that from beef is studied. For this purpose, defatted lean meat cuts from Beef, Baladi-goat and Awassi-sheep were collected, weighed and processed following the EU-approved guidelines for Bresaola della Valtellina. The bresaola from beef (BFB) had the significantly lowest moisture and fat content compared to Bresaola from Baladi-goat (BFG), with the values of Bresaola from Awassi-sheep (BFS) being significantly the highest. Furthermore, the protein and ash content of BFB was significantly the highest, followed by the values of BFG with content of BFS being the lowest. The pH value of BFB was significantly the lowest, while there was no difference between those of BFG and BFS. There was no significant difference in the water activities of BFB, BFG and BFS (0.848±0.002). As for the colorimetric characteristics, the ΔE value of BFB with BFG is 14.74±4.10, while that of BFB with BFS is 17.88±4.10, and that of BFG with BFS is 16.00±4.10 noting that the values did not differ significantly. The BFB and BFG Hue values did not differ significantly both being significantly larger than that of BFS. The BFB and BFG Chroma values were not significantly different while both being significantly different from that of BFS. Bresaola from raw meat (kg-Bresaola/kg-raw meat) value for beef was found to be significantly higher than that of goat, with value for sheep being significantly the highest. Consequently, the opposite was true for weight loss (%).
Migration and Refugee Crisis in Poetry: Birth of Bangladesh
Authors: Das Arunav
Published: March 2023

This study will focus on the refugee crisis and migration due to the idea of nationalism in the poetry of Jibanananda Das’s “1946-47” and Allen Ginsberg’s “September on Jessore Road.”. There is an affinity between the experiences of the two poets. Das’s “1946-47” theme focuses on the refugee crisis and communal violence during the subcontinent's partition in 1947. On the other hand, Ginsberg experienced the refugee crisis on his travels to India during the liberation war of Bangladesh in 1971. His famous poem “September on Jessore Road” describes the suffering of the refugees due to the genocidal attack by the Pakistani Army. Both poems are instrumental in poetic form and content regarding the contemporary refugee crisis in East Pakistan (present-day Bangladesh). Das and Ginsberg also witnessed and acknowledged the social and political turmoil on both sides of the Bengal delta due to the uprising of extreme nationalism and religious identity in the subcontinent. So, this study will follow Benedict Anderson’s idea of “imagined communities” as the critical evidence. This paper will conceptualize and analyze how the paradoxes of nation and nationalism enable both poets to portray the complexities of migration, calamities of refugees, and humanitarian crises in these two historical poems.
SoulBound E-Voting System
Authors: Seth Ayush , Narang Dr. Sudha , Sagar Aayush , Jain Siddhant
Published: March 2023

Abstract: The right to vote is a fundamental right of citizens of democratic countries around the world. This is necessary so that citizens have a say in the choice of who represents them or in matters affecting them. The aspects of security and transparency are still threats from widespread elections with traditional systems. For years, democracies around the world have moved from sticking to paper ballots to electronic voting machines. These machines are not tamper-proof despite system checks, security procedures and election protocols. However, hacking and tampering with these machines is becoming more frequent as the number and methods of attackers increase. Physical access to the EVM, even for a few minutes, is enough to crack it. To ensure a fair and reliable election process, safety and security must be ensured throughout the process. A single organization still exists to administer the centralized system used for general elections. When organizations have complete control over their databases and systems, they can disrupt the database of important opportunities, which can cause a lot of problems in traditional election systems. Because networked software devices are vulnerable, the proposed work applies security concepts based on popular blockchain technology. It is currently being implemented with the goal of securing online money transactions in the digital economy. Blockchain has paved the way for cryptocurrencies such as Bitcoin and Ethereum. A blockchain is a distributed and non-translatable ledger in which data is added and updated in real time based on the consensus of nodes running software on the network. However, once data is added to the registry, you cannot delete or edit the data from the database. Therefore, counterfeit voting is impossible, increasing the reliability of the electronic voting system. As a result, governments around the world are exploring blockchain as a means to make general elections tamper-proof and transparent, with the goal of enabling a system where everyone trusts data and is tamper-proof. Using blockchain for database distribution of electronic voting systems can reduce one of the sources of fraud in database manipulation.
Smart Aquarium Monitoring System Using IoT
Authors: R Likitha , M G Madhuri , N M Sanjana , D Manisha , A P Asst Prof. Kavya
Published: March 2023

Abstract: Smart aquarium monitoring system is an automatic system that is taking care of the pet fish in the aquarium is a tedious process and should be properly set up and maintained in a healthy manner or else the fish will be destined for an unpleasant and short period of life. Therefore, it is critical to monitor aquarium conditions and improve the water quality of the mini aquarium tanks. Fishes require the utmost care, they need some specific conditions like a temperature level, pH, and suitable oxygen. The aquarium in which they are kept should contain proper monitoring parameters to keep it in good health condition. The parameters include automatic fish feeding motor temperature, pH, and dissolved oxygen level indicators. They can be accessed through a database that stores the values determined by the indicators where we can connect the database to the developed IoT mobile application and get information in mobile. This reduces human effort and errors in owning an aquarium full of aquatic animals and prevents unusual death of fish.
Experimental Study on the Subgrade Soil Stabilization using Lime Stone Powder
Authors: Sammarwar Sachin Kumar , Kirar Dr. Bablu
Published: March 2023

Abstract: A good road network is a basic infrastructure required for rapid economic growth, and this road network fails mainly due to weak subgrade, less infiltration capacity, landslide etc.,. Use of lime stone powder material has become popular in the construction industry In this case study, an attempt is being made to stabilize the subgrade soil using Lime Stone powder . Expansive soils are the most challenging soils to work with because of their tendency to swell and expand when exposed to varying moisture levels. Many structures for civil engineering have been damaged as a result. The presence of expansive subgrade soil causes discomfort to the pavement and pavement deterioration. In order to solve the issue, thick layers of expanding soil must be removed and replaced with competent material, which is very expensive in terms of time and money-consuming due to long hauling distances. In this study, the expansive subgrade soil was stabilised using lime. The VIDISHA-BHOPAL NH-146 RANGAI GHAT Road is where the soil was collected. The free swell index test, Atterberg limit test, Proctor test, California Bearing Ratio Tests, and swelling potential were used to compare the attributes of treated and untreated soils. Lime was used to treat the subgrade soil that are superior to onather material results when mixed with soil at various percentages, such as 5%, 10%, 15%, and 20%. according to the soil's weight. Based on the results of the soaked CBR, MDD, and OMC, as well as the 20% Lime Stone, the CBR value increase.
On Integer Solutions of the Ternary Quadratic Equation
Authors: Janaki G. , Aruna M.
Published: March 2023

Abstract: Analysis is conducted on the non-trivial different integral solution to the quadratic equation
Proper Colourings in r-Regular Modified Zagreb Index Graph
Authors: Litta Dr. E. , Dharshini S. Maragatha
Published: March 2023

Abstract: In this article, the new concept proper colourings in r - regular Modified Zagreb index graph has been introduced. The first and second Modified Zagreb indices are introduced. In this article, new inequalities on chromatic number related with first and second Modified Zagreb indices are being established.
AI Based Mental Health Prediction System
Authors: Desai Prof. M.P. , Nagapurkar Swarnima , Gajbhiye Nia , Patil Vedantika , Solunke Akash
Published: March 2023

Abstract: The most common mood disorder in the world, depression has a considerable negative influence on health and functionality as well as profound personal, familial, and society implications. The correct and timely identification of depressionrelated symptoms may have numerous advantages for both doctors and those who are affected. The current work aimed to develop and clinically test a system capable of identifying visual signs of melancholy and supporting physician decisions. Programmable suffering assessment based on visible signals is a rapidly expanding research area. Picture handling and AI computations are the focus of the current thorough evaluation of existing approaches as described in more than sixty distributions during the last 10 years. The current datasets, various information-gathering methods, and visual cues of misery are compiled. The survey depicts estimates for visual element extraction, dimensionality reduction, layout and relapse choosing options, as well as numerous combination techniques. Incorporating a quantitative meta-analysis of announced results based on execution metrics risk-tolerant, it identifies general trends and significant irksome issues to be taken into account in ongoing investigations of programmed sadness appraisal using visible signs either alone or in combination with obvious signals. Additionally, the proposed work used deep learning to predict the level of the downturn as shown by the contribution of current face photographs.
Adaption of Best Methodology by Comparing Different Algorithm to Detect Parkinson Disease
Authors: Kesarwani Vaibhav , Mishra Gunjan , Chauhan Rishabh Kumar , Ranjan Sanjeev , Singh Saurabh Kumar
Published: March 2023

Abstract: Early and accurate prediction of Parkinson's disease (PD) can play a crucial role in improving its management and outcome. The aim of this study was to identify the best methodology for PD prediction. A comprehensive review of various prediction methods, including machine learning algorithms such as Support Vector Machines, Random Forest, and Neural Networks, was conducted. The performance of these methods was evaluated using metrics such as accuracy, sensitivity, and specificity. The findings revealed that a combination of Random Forest and Neural Networks emerged as the best approach for PD prediction, providing high accuracy and robust performance. This highlights the significance of selecting the appropriate prediction method for PD and the advantages of using a combination of algorithms for improved prediction.
Nanotechnology in Medical Field
Authors: T. P Ajay Kumar , V. G. Santheep Krishna , K. H. Aakila
Published: March 2023

Abstract: Nanotechnology is the field of using the technology and science that focuses on using molecular level regulation of matter that are of size range less than 100 nm range. In the field of nanotechnology, there are two primary approaches. The two main approaches are “Top-down” approach and “Bottom-up” approach. With a “Bottom-up” approach, materials and gadgets made of molecules that chemically put themselves together using molecular recognition principles are used. The nano-objects are created from larger entities using “Top-down” approach without atomic-level control. In fact, nanotechnology has been useful in a variety of medical fields, including cardiovascular medicine, oncology and the treatment of other chronic illnesses, as there is a significant need for the creation of pharmaceuticals and because the biological elements of live cells play crucial functions at the nanoscale. Undoubtedly, nanotechnology is being utilised to improve the identification of biomarkers, medication development, drug delivery and molecular diagnostics, all of which may be useful in the treatment of these patients. The imp
Efficient Authentication in RFID Devices Using Et Als Algorithm
Authors: Patil Mr. Dhiraj , Aalam Dr. Zahir
Published: March 2023

Abstract: Security plays a vital role during the transmission of private data from one sender to the other. Although there are many security algorithms implemented but here we are providing the security algorithms on the RFID devices. The authentication techniques implemented in RFID is based on the new algorithm based on smart cards. The data send through the tags can be made secure using the proposed algorithm so that the unauthorized users can’t access the data without any further unique numbers
Prediction of ICU Admission for Covid-19 Patients: A Machine Learning Approach Based on Complete Blood Count Data
Authors: Bruxella Dr. J. Mary Dallfin , Raint T. S. Linda Mary
Published: March 2023

Abstract: In this post, we talk about how to create prognostic Machine Learning (ML) models for COVID-19 progression. Specifically, we talk about how to forecast who willneed to be admitted to the intensive care unit (ICU) in the next five days.On the basis of 4995 Complete Blood Count (CBC) tests, we created three ML models.We propose three ML models that differ in terms of interpretability: two fully interpretable models and a blackbox one.We report an AUC of .81 and.83 for the interpretable models (the decision tree and logistic regression, respectively), and an AUC of .88 for the black-box model (an ensemble).This demonstrates how CBC data and machine learning techniques can be used to predict the cost-effectiveness of ICU admission for COVID-19 patients.In particular, because the CBC can be quickly obtained through routine blood tests, our models could be used in settings with limited resources and to quickly provide indications at triage and daily rounds.
Security Challenges in Cloud Computing
Authors: S Anjali M. , Harshan Ananya , V Claijo Kurian
Published: March 2023

Abstract: The most technological trend in the IT world is cloud computing, and because of its youth, both its users and its manufacturers have certain concerns. Looking over its literature, we can observe that the primary issues are trust, privacy, and security. That makes a significant barrier for users to use. Hence, to determine whether cloud computing would be accepted, we decided to assess various issues, including security. In this article, the security paradigm was the central issue, focusing on privacy safeguards and the need for trustworthiness to implement cloud computing. As a by-product, we have suggested radical innovations for enhancing security, reducing risks, improving trust, and protecting consumers, which are crucial for the adoption of cloud computing.