bluuebunny/crossref_metadata_2025 huggingface dataset:
DERMATITE PERIORAL GRANULOMATOSA COM ACOMETIMENTO EXTRAFACIAL NA INFÂNCIA: BOA RESPOSTA TERAPÊUTICA COM USO DE AZITROMICINA ORAL
Authors: Milagre Ana Carolina Xavier , Almeida Ana Paula Moura de , Rezende Hudson Dutra , Almeida Liana Moura de , Peçanha Maria Auxiliadora Peixoto
Published: July 2018

RESUMO Objetivo: Apresentar um caso de dermatite perioral granulomatosa (DPG) com acometimento extrafacial e resposta terapêutica satisfatória ao uso de macrolídeo oral por curto período. Descrição do caso: Escolar de nove anos, sexo feminino, com quadro exuberante de DPG com acometimento extrafacial. Durante o período de evolução, submeteu-se a múltiplas terapêuticas ineficazes, apresentando melhora significativa das lesões após o uso de azitromicina por cinco dias. Comentários: A DPG é uma afecção dermatológica inflamatória representada por erupções papuloeritematosas em região perioral, nasal e periorbitária, mais comum em crianças e adolescentes. Raramente estende-se à região genital, ao tronco e às extremidades, caracterizando o comprometimento extrafacial. De etiologia ainda desconhecida, parece apresentar correlação com uso de corticosteroides tópicos e outros agentes.
CARCINOMA ADRENAL EM CRIANÇAS: ESTUDO LONGITUDINAL EM MINAS GERAIS, BRASIL
Authors: Monteiro Nonato Mendonça Lott , Rodrigues Karla Emília de Sá , Vidigal Paula Vieira Teixeira , Oliveira Benigna Maria de
Published: July 2018

RESUMO Objetivo: Analisar as características clínicas, laboratoriais e histopatológicas e o percurso até o estabelecimento do diagnóstico e do tratamento de pacientes com carcinoma de suprarrenal (CSR). Métodos: Estudo retrospectivo com 13 pacientes tratados no serviço de oncologia pediátrica do Hospital das Clínicas da Universidade Federal de Minas Gerais (HC-UFMG) entre 2004 e 2015. Resultados: A idade ao diagnóstico variou de 1,0 a 14,8 anos (mediana: 2,0 anos). As manifestações de hipercortisolismo foram identificadas em todos os casos, e as de virilização, em todas as meninas. Todos os pacientes preencheram os critérios de Weiss para diagnóstico histopatológico de CSR. A imuno-histoquímica foi realizada em 61,5% dos casos. A maioria dos pacientes apresentou doença em estádio I (76,9%). Todos foram submetidos à ressecção tumoral total. Dois pacientes (estádios III e IV) receberam quimioterapia associada ao mitotano. O único óbito observado foi do paciente com doença em estádio IV. A probabilidade de sobrevida global para todo o grupo aos 5,0 anos foi de 92,3±7,4%. A mediana de tempo entre o início dos sintomas e o diagnóstico foi de 9,5 meses, e de 6,0 meses entre a primeira consulta e o início do tratamento. Conclusões: A baixa idade ao diagnóstico, o predomínio de casos com doença localizada e a ressecção tumoral completa - com apenas um caso de ruptura de cápsula tumoral - são possivelmente a explicação para a evolução favorável da população estudada. O longo percurso entre o início dos sintomas e o diagnóstico sugere a importância da capacitação dos pediatras para o reconhecimento precoce dos sinais e dos sintomas do CSR.
O Ensino de Evolução Biológica e sua Abordagem em Livros Didáticos
Authors: Zamberlan Edmara Silvana Joia , Silva Marcos Rodrigues da
Published: July 2018

RESUMO Apesar de ser considerada como uma ideia reguladora para toda a biologia, geralmente a evolução é tratada, nos livros didáticos brasileiros de biologia, como um conteúdo; assim a evolução é geralmente considerada, nestes livros, da mesma forma que qualquer outro conteúdo. Além disso, outros conteúdos, que deveriam ser considerados a partir de uma compreensão prévia do conceito de evolução, são abordados com referência apenas implícita à evolução. O objetivo deste trabalho é o de, por meio de uma análise de alguns livros didáticos de biologia do ensino médio, descrever e discutir a forma de apresentação dos conteúdos de competição e vírus, e verificar como está sendo realizada tal apresentação.
Do Nada ao Tudo: políticas públicas e a educação especial brasileira
Authors: Machado Jardel Pelissari , Pan Miriam Aparecida Graciano de Souza
Published: July 2018

RESUMO Este trabalho analisa o discurso de inclusão da Política Nacional de Educação Especial na Perspectiva da Educação Inclusiva (PNEEPEI, 2008) e os efeitos de sentido que produz em suas relações dialógicas. Trata-se de um estudo documental da legislação brasileira e de declarações das quais o Brasil é signatário, com base na filosofia bakhtiniana da linguagem. Discute como a nova política transforma os sentidos de práticas de instituições de educação especial em discriminatórias e produz o apagamento de diferenças humanas como mecanismo de garantia de direitos. Conclui-se sobre a necessidade de reflexão e avaliação das políticas públicas e de seus efeitos no âmbito da educação, repensando-a como instituição social contraditória.
Infância e Cidade: Porto Alegre através das lentes das crianças
Authors: Müller Fernanda
Published: July 2018

RESUMO O artigo analisa as visões das crianças sobre a cidade que habitam. A partir de uma perspectiva metodológica de inspiração etnográfica, o estudo acompanhou um grupo de nove crianças, de quatro a doze anos, moradoras de três diferentes bairros da cidade de Porto Alegre. O principal objetivo do trabalho é explorar como as crianças entendem suas vidas na cidade. As crianças foram convidadas a fotografar os lugares da cidade os quais consideravam importantes nas suas vidas, o que foi seguido de conversas gravadas e transcritas. A análise se concentra nos espaços delimitados pelas crianças nas fotografias, sejam eles criados por elas ou para elas. As crianças também apresentam suas opiniões, preocupações e medos, o que evidencia a necessidade de serem ouvidas e de participarem das discussões sobre a cidade em que vivem.
Educação para a Inteireza do Ser - uma caminhada
Authors: Pozatti Mauro Luiz
Published: July 2018

RESUMO Ao percorrer uma caminhada entre medicina e educação nos últimos trinta anos, o autor desenvolve uma proposta teórica e prática para reposicionar o ser humano enquanto um todo inteiro - corporal, mental, social, cultural, ambiental e espiritual - o qual, por sua vez, também é parte de um Todo e em permanente conexão com o mesmo. Esta proposta está em sintonia com a visão de mundo transdisciplinar e holística. Além de redirecionar o conceito de saúde, o autor também propõe processos educacionais complementares, incluindo uma educação de acordo com as fases de vida e a convivência harmônica e voltada ao desenvolvimento da consciência em relação à Totalidade.
O Tocar na Relação de Cuidado Baseada no Sensível
Authors: Bois Danis , Bourhis Hélene
Published: July 2018

RESUMO Este artigo visa a introduzir a relação de ajuda manual no campo da educação para a saúde. Argumentamos em favor do interesse em se integrar a dimensão humana no tratamento dos pacientes, através do tocar relacional. O leitor encontrará um inventário da questão na França e descobrirá uma abordagem de acompanhamento baseada na mediação corporal fundamentada no Sensível.
Oficinas de Trabalho Biográfico: pesquisa, pedagogia e ecologia de saberes
Authors: Lechner Elsa
Published: July 2018

RESUMO O texto apresenta e desenvolve os pressupostos teóricos da proposta pedagógica que são as oficinas de trabalho biográfico junto de pesquisadores e estudantes universitários das ciências sociais e humanidades. São revisitadas as suas diversas etapas e contextualizada a proposta no quadro mais vasto da teoria da ecologia de saberes de Boaventura de Sousa Santos em equação com a corrente actual da pesquisa biográfica tal como esta é desenvolvida no quadro da associação internacional Le Sujet dans la Cité.
O ESPELHO DE MACUNAÍMA: O ENSAIO SOBRE MÚSICA BRASILEIRA PARA ALÉM DO NACIONALISMO
Authors: Hoelz Maurício
Published: July 2018

Resumo O artigo propõe um estudo analítico e a contrapelo do Ensaio sobre música brasileira de Mário de Andrade, publicado no final de 1928 e frequentemente considerado peça ideológica exemplar de rotinização de seu projeto nacionalista. Argumenta que o foco sobre a dimensão normativa acabou por cronicamente minimizar, senão eclipsar, a dimensão propriamente cognitiva do texto, obliterando as visões instrumental de nacionalismo e aberta de identidade aí formuladas ao discipliná-lo a partir do paradigma, que se tornaria hegemônico nos anos 1930, da unidade nacional e de uma cultura brasileira autêntica e homogênea. Sugere ainda que a ideia cosmopolita e descentrada de brasilidade do modernista expressa uma identidade aberta, plural e inacabada capaz de provocar o reconhecimento da cultura popular e da dignidade de seus portadores sociais.
COMPARING IDEOLOGIES OF RACIAL MIXING IN LATIN AMERICA: BRAZIL AND MEXICO
Authors: Silva Graziella Moraes , Saldivar Emiko
Published: July 2018

Abstract By the end of the twentieth century, with the rise of multicultural discourses and identity politics, Latin American ideologies of racial mixture had become increasingly denounced as myths that conceal (and thus support) the reproduction of racial inequalities. These studies have largely been guided by comparisons between countries with widespread racial mixing (usually Brazil, Mexico or Colombia) and countries in which it was less encouraged and visible (most commonly, the USA). In this paper we move the focus to the diverse ways in which racial mixture currently impacts racial formations in the Latin America, looking initially at Brazil and Mexico, two of the largest countries in the region, and also those with the largest Afro-descendent and indigenous populations in the continent. For comparison, we analyze survey data from the PERLA project.
Physiological performance of açai seeds (Euterpe oleracea Mart.) stored with different moisture contents and treated with fungicide
Authors: Lima Juliana Maria Espíndola , Oliveira João Almir , Smiderle Oscar José , Lousado André Vitor Carvalho , Carvalho Maria Laene Moreira de
Published: July 2018

Abstract: The expansion of açai production has increased the importance of management of seeds used for replanting or expanding the plantation areas. Thus, the aim of this work was to evaluate the performance of açai seeds with different moisture contents, treated or untreated with fungicide, and stored for 180 days. The seeds were divided into three moisture levels (35%, 30% and 20%), and with or without fungicide treatment, with four storage evaluation periods (0, 60, 120 and 180 days). They were packed in plastic bags and kept in natural environment. The experimental design was completely randomized, with a 3 x 2 x 4 factorial scheme (moisture contents x treated or untreated with fungicide x period of evaluation), with four replications of 50 seeds each. The following tests were conducted: moisture content, germination, tetrazolium test, seedling emergence, seedling emergence speed and X-ray. Açai seeds with 35% and 30% moisture contents treated with fungicide showed a better physiological quality in relation to the untreated ones. Storage longer than 120 days reduced seed germination to values below 50%, regardless of whether they were treated or not with fungicide, although the reduction was greater in untreated seeds. The fungicide treatment is efficient in controlling fungi in açai seeds with 30% and 20% moisture content for up to 180 days of storage, and in seeds with 35% moisture content for up to 60 days of storage.
A Comunicação Suplementar e Alternativa na percepção de familiares e fonoaudiólogos: facilitadores e barreiras
Authors: Romano Nátali , Chun Regina Yu Shon
Published: July 2018

RESUMO Objetivo Conhecer facilitadores e barreiras no uso da Comunicação Suplementar e Alternativa (CSA) na percepção de familiares/cuidadores e fonoaudiólogos que atuam com pessoas usuárias de CSA nos contextos familiar, social e terapêutico. Método Estudo transversal quantitativo e qualitativo com 20 fonoaudiólogos (GF) e 20 familiares e/ou cuidadores de usuários de CSA (GFC). Realizou-se a coleta de dados por meio de entrevistas semiestruturadas com questionários específicos para cada grupo, videogravadas e transcritas para análise. Os dados foram categorizados, conforme critérios de relevância e repetição, em dois eixos temáticos principais: barreiras e facilitadores, contendo categorias e subcategorias. Resultados Ambos os grupos apontaram como barreiras: custo dos materiais, utilização de outras formas de comunicação, familiar como intérprete, dificuldades linguístico-cognitivas e de aceitação de uso da CSA pelos usuários, falta de compreensão/conhecimento da CSA pelos familiares e inibição da fala na percepção dos familiares. Ambos indicaram como facilitadores: utilização de recursos de alta tecnologia, versatilidade/disponibilidade, envolvimento/adesão familiar, uso contextualizado, importância do ambiente terapêutico, equipe e estratégias utilizadas. Conclusão Os principais interlocutores na implementação da CSA, profissionais ou familiares, podem se constituir como barreiras quando dificultam os usuários de exercer sua autonomia na comunicação ou facilitadores quando incentivam e utilizam a CSA com os usuários.
Estrategias de evaluación en la narración como tarea metacognitiva en personas con esquizofrenia
Authors: Barra Alicia Figueroa , Mac-Kay Ana Paula Machado Goyano , Lara Eduardo Durán
Published: July 2018

RESUMEN Objetivo Este estudio procura explorar las diferencias en el componente evaluativo de la estructura narrativa en personas con diagnóstico de esquizofrenia, en comparación con personas con diagnóstico de psicosis afectiva. Método El presente estudio es descriptivo, no experimental, y comprende el análisis de los componentes evaluativos de la narrativa, en entrevistas realizadas a 25 individuos con diagnostico psiquiátrico de esquizofrenia crónica y a 25 individuos diagnosticados de psicosis afectiva crónica, pareados por edad, género y características sociodemográficas. Resultados La relación entre diagnóstico y tipo de evaluación arrojó resultados estadísticamente significativos con un valor de chi cuadrado de 39,880a (p< 0.00). Fue posible observar que en la esquizofrenia existe una mayor inhibición en la elaboración de expresiones que impliquen opiniones, que los relatos tendieron a identificar los hechos independientemente de cómo les afectaron, sugiriendo una limitación de la función intersubjetiva. Conclusión La variable diagnóstico confirma que en la esquizofrenia existe un deterioro funcional en la elaboración de estructuras narrativas y en la articulación del componente evaluativo. En el caso de la psicosis afectiva se manifiestan disfunciones superficiales, sin comprometer su desempeño en la evaluación de las narraciones.
Auditory maturation and psychological risk in the first year of life
Authors: Rechia Inaê Costa , Fattore Isabela de Moraes , Moraes Anaelena Bragança de , Biaggio Eliara Pinto Vieira , Souza Ana Paula Ramos de
Published: July 2018

ABSTRACT Purpose To assess the potential association between psychological risk and limited auditory pathway maturation. Methods In this longitudinal cohort study, 54 infants (31 non-risk and 23 at-risk) were assessed from age 1 to 12 months. All had normal hearing and underwent assessment of auditory maturation through cortical auditory evoked potentials testing. Psychological risk was assessed with the Child Development Risk Indicators (CDRIs) and PREAUT signs. A variety of statistical methods were used for analysis of results. Results Analysis of P1 and N1 latencies showed that responses were similar in the both groups. Statistically significant differences between-groups were observed only for the variables N1 latency and amplitude at 1 month. Significant maturation occurred in both groups (p<0.05). There was moderate correlation between P1 latency and Phase II CDRIs, which demonstrates that children with longer latencies at age 12 months were more likely to exhibit absence of these indicators in Phase II and, therefore, were at greater psychological risk. The Phase II CDRIs also correlated moderately with P1 and N1 latencies at 6 months and N1 latencies at 1 month; again, children with longer latency were at increased risk. Conclusion Less auditory pathway maturation correlated with presence of psychological risk. Problems in the mother-infant relationship during the first 6 months of life are detrimental not only to cognitive development, but also to hearing. A fragile relationship may reflect decreased auditory and linguistic stimulation.
Combination of the SCS-CN and the GRADEX models to maximum flow estimation
Authors: Mota Tainá , Naghettini Mauro , Fernandes Wilson , Silva Francisco
Published: July 2018

ABSTRACT The absence of hydrometric monitoring of adequate extension, periodicity, temporal resolution and quality is the Brazilian reality in many drainage basins. It’s common the use of rainfall-runoff models of simple application to determine rainfall excess volumes, such as the SCS-CN method. Although the SCS method is broadly accepted, many authors have questioned the results derived from its application to catchments with distinct characteristics than those studied during its original formulation. An alternate method for maximum flow estimation in catchments with scarce monitoring is the GRADEX method, which proposes extrapolation of the flood volumes’ frequency curve from precipitation series. Despite being a consolidated method, it is rarely used in Brazil because of the difficulties found in fulfilling its initial hypotheses. This paper suggests, therefore, the combination of both methods, aiming for a methodology that better describes the uncertainties involved in the determination of the direct flood volumes’ probability distribution. The case study is conducted on the Serra Azul river catchment, Juatuba – MG, which offers 12 years of continuous records. The referred combination occurs on the definition of the lower and upper boundaries of the probability distribution of global water retention in the soil and in the catchment, as embedded in the GRADEX method, from the CNASYMPTOTIC concept. The modelled scenarios bear evidence of the many possibilities that may exist in the extrapolation of the frequency curve of surface runoff volumes suggests a range of results that better underpins the definition of the saturation condition and, consequently, the maximum rainfall excess calculation, as compared to the originally proposed methods.
Relationships between pacific and atlantic ocean sea surface temperatures and water levels from satellite altimetry data in the Amazon rivers
Authors: Silva Mylena Vieira , Paris Adrien , Calmant Stéphane , Cândido Luiz Antonio , Silva Joecila Santos da
Published: July 2018

ABSTRACT The influence of SST (Sea Surface Temperature) of adjacent oceans on the variability of water levels in the Amazon basin was investigated by using radar altimetry from the ENVISAT and Jason-2 missions. Data from the in situ network was used to compare the correlations of water level and SST anomalies in the sub-basins of the Amazonas-Peru, Solimões, Negro and Madeira Rivers. The analysis was made on the monthly and annual scales between 2003 and 2015. The correlations with anomalies of levels from altimetry presented higher accuracy indices than those from the conventional network. In general, ATN and PAC are better correlated with the entire basin. During the flood months, most of the sub-basins presented negative associations with ATN. In the months of ebb, the response to the indexes varies according to the region. The satellite altimetry data permitted to reach regions non-monitored by the conventional network. We also analyzed the impacts of hydrological extremes in all these sub-regions in the last 13 years. In Western Amazon, the drought of 2010 stands out, associated with the warming of the Tropical Atlantic and the El Niño. In the Negro River, the water level anomalies were the lowest in the basin during the 2005 drought. In the Purus River, the effects of the 2010 drought that affected the entire Amazon, were higher in 2011 due to its strong relationship with the Atlântic and Pacific oceans. In general, hydrological extremes are stronger or highlighted when SST increases simultaneously in both oceans.
Alternative methodology to gap filling for generation of monthly rainfall series with GIS approach
Authors: Bielenki Junior Claudio , Santos Franciane Mendonça dos , Povinelli Silvia Cláudia Semensato , Mauad Frederico Fábio
Published: July 2018

ABSTRACT As an alternative to Gap filling in monthly average rainfall series, we attempted to present a methodology for the generation of series only with the observed data available in the rainfall stations present in the study area and its surroundings. For this, a computational tool was developed with a GIS approach, using scripts in the Python language, to automate the study steps. Two calculation alternatives for the mean precipitation, variable Thiessen polygons or variable inverse distance weights (IDW), were considered. Random gaps were imposed from a series of data without gaps allowing us to evaluate the presented methodology. The results of the series calculated according to this methodology were compared to two methods of Gap filling. The behavior of the series was evaluated through the analysis of position and dispersion measurements as well as the temporal behavior by the evaluation of the correlograms and periodograms. The results are found to be satisfactory, which demonstrates the equivalence of the proposal with results found with the gap filling methods under the tested conditions. The differences found between the series were small, which was reflected in the Nash-Sutcliffe Indexes. There were no significant differences between the calculation alternatives by Thiessen polygons or IDW weights.
OS PRIMEIROS CACHORROS: ENCONTROS INTERÉTNICOS E MULTIESPECÍFICOS NO SUDOESTE DA AMAZÔNIA
Authors: Velden Felipe Ferreira Vander
Published: July 2018

Narrativas coloniais que tratam da presença de cachorros europeus nos encontros entre índios e brancos nas Américas frequentemente retratam o papel instrumental desses animais como armas terríveis. Para os colonizadores, assim, cachorros foram eficazes ferramentas de submissão dos povos nativos que encontraram a partir do século XV. No entanto, analisar com atenção as narrativas indígenas de muitos desses primeiros encontros pode mostrar perspectivas distintas, que apresentam cães não apenas como instrumentos de conquista, mas também como agentes, atuando sobretudo como facilitadores do contato entre indígenas e não indígenas. Este artigo explora histórias sobre os primeiros cachorros conhecidos por duas populações nativas no estado de Rondônia (Brasil), com o objetivo de sugerir a agência canina nos encontros interétnicos. Argumenta-se, então, que os primeiros contatos entre indígenas e brancos são eventos que não incluem apenas dois grupos de humanos, posto que as ações dos cachorros têm papel crucial no desenvolvimento das interações humanas. Desse modo, encontros interétnicos podem ser também encontros multiespecíficos.
EMPODERAMENTO, AMIZADE E CUIDADO DE SI. Novas formas de relação de assistência à saúde
Authors: Lopes Andreia Aparecida Ferreira
Published: July 2018

O artigo analisa o modo como os grupos de educação em saúde que congregam pessoas com diabetes promovem o empoderamento de seus membros, estimulando processos de reestruturação das relações mais tradicionais de assistência à saúde. A pesquisa que originou o texto apoia-se em metodologia qualitativa, envolvendo a etnografia dos “grupos de saúde” de uma associação de diabéticos no município de São Paulo e de um Centro de Saúde no município de Campinas (SP). Foram realizadas entrevistas com seus membros, sobretudo mulheres, com idades entre 53 e 87 anos e pertencentes às camadas populares, com o intuito de explorar características de sociabilidade desenvolvidas nesses grupos. Para tanto, considerou-se a amizade uma categoria relevante à compreensão do modo como se caracterizam as novas práticas de cuidado com a saúde, contrastando com relações mais tradicionais como as de caráter familiar. O quadro aponta a dinâmica de reencantamento das relações no espaço público, no contexto da modernidade reflexiva.
BANCADA SINDICAL, POLÍTICA PREVIDENCIÁRIA E PROCESSO DECISÓRIO NO GOVERNO DILMA
Authors: Silva Sidney Jard da
Published: July 2018

Esse trabalho analisa a participação dos parlamentares sindicalistas (deputados e senadores) no processo decisório de criação da Fundação de Previdência Complementar do Servidor Público Federal (Funpresp), no primeiro mandato do governo Dilma Rousseff (2011-2014). O problema de pesquisa é formulado nos seguintes termos: em condições político-institucionais em que a bancada sindical faz parte da coalizão governista, como se posicionam os parlamentares sindicalistas em matérias que contrariam interesses de setores importantes da sua base de representação social? Os achados da investigação reforçam a tese da predominância partidária no Legislativo brasileiro. A maioria dos legisladores sindicalistas, inclusive os originários do setor público, votou favoravelmente à aprovação do Projeto de Lei n. 1992/2007, que criou a Funpresp, mesmo sob pressão contrária dos servidores públicos federais e de suas entidades representativas.
FECAL OCCULT BLOOD: A COMPARISON OF CHEMICAL AND IMMUNOCHEMICAL TESTS
Authors: BORGES Luana Vilarinho , MATTAR Rejane , SILVA Joyce Matie Kinoshita da , SILVA Ana Luiza Werneck da , CARRILHO Flair José , HASHIMOTO Cláudio Lyoiti
Published: July 2018

ABSTRACT BACKGROUND: Colorectal bleeding is a warning sign that may be identified by fecal occult blood testing. A positive fecal occult blood test result requires a subsequent colonoscopy, a costly and invasive examination. Therefore, the use of diagnostic tests with optimal sensitivity and specificity is warranted. In this study, we evaluated four different fecal occult blood tests in 176 patients undergoing colonoscopy and compared their results. OBJECTIVE: To assess the sensitivity, specificity and predictive values of chemical and immunochemical fecal occult blood tests in patients undergoing colonoscopy and to evaluate the degree of concordance between the tests and colonoscopy. METHODS: Patients with indications for colonoscopy also underwent fecal occult blood testing by chemical (toluidine test) and immunochemical methods, employing three commercially available kits. Based on the endoscopic findings, the colonoscopy was rated as positive or negative for colorectal bleeding. The degree of concordance between the fecal occult blood tests and the colonoscopy was evaluated by the kappa index. RESULTS: Forty-four (25%) colonoscopies were categorized as positive for colorectal bleeding. The toluidine test presented lower concordance than the immunochemical tests, which showed moderate concordance with the colonoscopy. The toluidine test had the least sensitivity, specificity, and positive and negative predictive values. CONCLUSION: The immunochemical fecal occult blood tests showed greater sensitivity, specificity and predictive values in detecting colorectal bleeding. The immunochemical tests had superior indexes of agreement with colonoscopy compared to the toluidine test.
INTRACELLULAR PERSISTENCE OF ENTEROAGGREGATIVE ESCHERICHIA COLI INDUCES A PROINFLAMMATORY CYTOKINES SECRETION IN INTESTINAL EPITHELIAL T84 CELLS
Authors: BRAGA Ricardo Luís Lopes , PEREIRA Ana Claudia Machado , FERREIRA Andréa Fonseca , ROSA Ana Cláudia de Paula , PEREIRA-MANFRO Wânia Ferraz
Published: July 2018

ABSTRACT BACKGROUND: The competence of enteroaggregative Escherichia coli (EAEC) to adhere to the intestinal epithelium of the host is a key role to the colonization and disease development. The virulence genes are crucial for EAEC pathogenicity during adherence, internalization and persistence in the host. The overwhelming majority of antigen encounters in a host occurs on the intestine surface, which is considered a part of innate mucosal immunity. Intestinal epithelial cells (IECs) can be activated by microorganisms and induce an immune response. OBJECTIVE: The present study investigated the interaction of invasive EAEC strains with T84 intestinal epithelial cell line in respect to bacterial invasiveness, persistence and cytokines production. METHODS: We evaluated intracellular persistence of invasive EAEC strains (H92/3, I49/3 and the prototype 042) and production of cytokines by sandwich ELISA in T84 cells upon 24 hours of infection. RESULTS: The survival rates of the prototype 042 was 0.5x103 CFU/mL while survival of I49/3 and H92/3 reached 3.2x103 CFU/mL and 1.4x103 CFU/mL, respectively. Infection with all EAEC strains tested induced significant amounts of IL-8, IL-6 and TNF-α compared to uninfected T84 cells. CONCLUSION: These data showed that infection by invasive EAEC induce a proinflammatory immune response in intestinal epithelial T84 cells.
HEALTH-RELATED QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH RECTAL CANCER TREATED WITH CURATIVE INTENT
Authors: SOUZA José Luís da Costa Alves de , NAHAS Caio Sergio Rizkallah , NAHAS Sergio Carlos , MARQUES Carlos Frederico Sparapan , RIBEIRO JÚNIOR Ulysses , CECCONELLO Ivan
Published: July 2018

ABSTRACT BACKGROUND: The treatment of median and distal rectal cancer has evolved a lot in the last decades due to the dissemination of the technique of total mesortal excision and the use of neoadjuvant chemotherapy and radiotherapy. However, this multidisciplinary approach can affect patients’ quality of life in a number of ways that deserve to be adequately assessed. OBJECTIVE: To evaluate immediate and late health related quality of life in patients with rectal cancer treated with curative intent. METHODS: Prospective study including patients with non-metastatic mid or low rectal cancer. EORTC QLQ-C30 and EORTC-CR38 questionnaires were applied before, 3 months and 12 months after treatment. The mean scores of the questionnaires were stratified into 4 categories for the purpose of comparing the results at different moments. RESULTS: Twenty nine patients completed the 1st and 2nd questionnaires and 12 completed the three questionaries. Patient´s mean age was 50.8 years and 62% were female. Sphincter preservation was possible in 89.6%. Overall health scores and quality of life improved after three months after 12 months. After three months, sexual satisfaction, female sexual problems and future perspective were worsen, but gastrointestinal symptoms, sphincter problems, and weight loss were improved. After 12 months the Future Perspective deteriorated, but there was improvement of the problems related to stoma, sphincter problems and body image. CONCLUSION: Despite the complexity of the treatment of rectal cancer within a specialized service, quality of life was preserved and was satisfactory in most of the studied aspects.
INCREASE OF LIPIDS DURING HCV TREATMENT: VIRUS ACTION OR MEDICATION?
Authors: ANDRADE Vanessa Gutierrez de , YAMASHIRO Fabio da Silva , OLIVEIRA Cassio Vieira , KUROZAWA Leticia Lastória , MOREIRA Alecsandro , SILVA Giovanni Faria
Published: July 2018

ABSTRACT BACKGROUND: The interaction between serum lipids and C virus infection is well known, as are serum lipid levels in the Peg-IFN / RBV-based treatment. However, with direct action antivirals (DAAs) this behavior is still unclear. OBJECTIVE: To compare serum lipids levels between patients treated with Peg-IFN/RBV and DAAs and to evaluate lipids in sustained virological response (SVR) with DAAs. METHODS: Retro prospective study comparing the behavior of total cholesterol (TC), low-density lipoprotein (LDL) and triglycerides (TG) serum levels during treatment with DAAs (G-DAAs) and a control historic group Peg-IFN/RBV (G-PR). Coorte, prospective study, to study the behavior of lipids in the SVR with DAAs. Data were collected at the beginning of treatment (baseline: t-base) and at week 12 of treatment (t-12) for G-DAAs and at week 24 (t-24) for G-PR, groups. In the cohort evaluation, the samples at t-base and at week 12 after the end of treatment (t-SVR). Delta lipids: difference between lipids in t-12 / t-24 minus t-base for comparison between G-PR and G-AADs groups and t-SVR minus t-base for lipid analysis in SVR. Analysis with Kruskal Wallis and Wilcoxon tests to compare the delta lipids of the groups. The P value was 0.05. RESULTS: In the assessment between G-PR and G-DAAs groups, we included 63 and 121 patients, respectively. The groups did not differ one from the other (BMI, sex, genotype, fibrosis, total cholesterol, LDL, and TG) except by age (50.38±10.44 vs 56±9.69, P=0.0006). We observed a decrease in levels of TC and LDL and an increase in TG, in G-PR, and in G-DAAs the opposite (Δ TC -13.9±34.5 vs 4.12±34.3 P=0.0005, Δ LDL -7.16±32 vs 10.13±29.92, P=0.003, Δ TG 4.51±53.7 vs -8.24±49.93, P=0.0025). In the coorte analysis, we included 102 patients, 70% men and 56% F4, 95 of them reached SVR. We observed an increase of TC and LDL and a decrease of TG in both groups (SVR and non SVR), with no statistical difference (Δ TC P=0.68; Δ LDL P=0.69; Δ TG P=0.43). We did not find significant difference in delta evaluation by genotype 1 and 3 (Δ TC +29.7±40.2 vs +13.4±30.3, P=0.06; Δ LDL +21.4±28.6 vs +16.6±31.3, P=0.41; Δ TG -3.6±60.6 vs -0.7±40, P=0.91). CONCLUSION: Serum lipids level differed during treatment with Peg-IFN and DAAs. Treatment with DAAs was associated with an increase of TC and LDL and a decrease of TG, independently of SVR.
Weeds Associated to Different Genotypes of Cocoa in the Ecuadorian Amazon Region
Authors: ALMEIDA J.F. , GARCÍA G.P. , PÉREZ R.A. , BRITO J.D.
Published: July 2018

ABSTRACT: This work was conducted in the Centro de Pesquisa, Pós-graduação e Preservação Amazônica (CIPCA), located in the Ecuadorian Amazon Region, with the goal to analyze the presence of weeds in promising clones of cocoa. The EET-95, EET-96 and EET-103 promising clones were evaluated, and the control sample was CCN-51. To do so, the relative frequency and distribution of the existing weeds were determined, as well as their biomass, which was statistically analyzed by the ANOVA of a factor and the HSD Tukey’s test. The presence of weeds was influenced by the studied genotypes, due to the fact that promising clones were associated to high frequency and distribution, such as Cyperus odoratus, Megathyrsus maximus, Sauvagesia erecta ssp. erecta. Other species appeared to be associated more to the CCN-51 clone, such as Scleria pterota, Paspalum conjugatuns and Rottboellia cochinchinensis. Higher weed biomass was verified in clone CCN-51.
Weed Phytosociological Survey in Irrigated Rice
Authors: NUNES F.S. , SCHAEDLER C.E. , CHIAPINOTTO D.M.
Published: July 2018

ABSTRACT: The phytosociological method helps evaluate the vegetation composition. The objective of this study was to identify and quantify the main weed species present in irrigated rice. The phytosociological survey was carried out in three mainly rice monoculture, Clearfield® technology using properties in Itaqui-RS, between 2013 and 2014. For each property and period, a ½ ha representative area was selected and 10 random samples were collected, using a quadrat square of 1 m2. The sample colletion was conducted in two periods of time: during the irrigated rice crop initial growth and during the cereal’s pre-harvesting phase. All collected plants were identified and counted, allowing for their frequency, relative frequency, density, relative density, abundance, relative abundance, relative importance index and similarity index to be calculated. Eleven weed species belonging to five families were identified. Poaceae and Cyperaceae occurred more frequently. During the initial growth of rice, the Poaceae family presented the largest index of relative importance, mainly to Echinochloa crus-galli, Echinochloa colona and Digitaria horizontalis. Overall, there was a reduction in plant density in the pre-harvest period. However, Echinochloa colona and Oryza sativa occurred in density levels that may interfere with the cereal yield. Aeschynomene denticulata, Cyperus iria and Oryza sativa are not controlled efficiently, indicating possible cases of herbicide resistance. Our conclusions emphasize the importance of correct weed species identification for the management of Echinochloa colona and Cyperus ferax. Integrated management practices are necessary for efficient weed control, avoiding productivity loss in the region’s flooded rice fields.
Interference Periods in Soybean Crop as Affected by Emergence Times of Weeds
Authors: ZANDONÁ R.R. , AGOSTINETTO D. , SILVA B.M. , RUCHEL Q. , FRAGA D.S.
Published: July 2018

ABSTRACT: Weeds emergence times modify competition with crops. Thus, the hypothesis was that the increase in weed emergence flow decreases the period prior to interference (PPI) in soybeans and increases the critical period of interference prevention (CPIP). The objective was to determine the PPI and the CPIP of weeds in soybean crops as affected by the preferred time of weeds emergence flow. Three experiments were conducted in the field in a randomized block design with four replications. The treatments were arranged in a factorial design with factor A consisting of coexistence or weed control in soybeans and factor B for eight periods (0, 7, 14, 21, 28, 35, 42 and 135 days after crop emergence (DAE)). The numbers of emerged plants and weed dry mass by genus and crop productivity were evaluated. The weed interference in culture during all the crop cycle reduces the soybean average yield 73, 94 and 89% in the first, second and third sowing times, respectively. Chemical control may be adopted at the end of PPI, which must be done at 14, 15 and 5 DAE crop, for the first, second, third times, respectively. The sowing in advance and intermediate time of recommendation increase the PPI in about 10 days, favoring the weed management in soybean crops.
Application of Plant Growth Regulators to Stipa krylovii in the Xilin Gol Grassland
Authors: JUN L.V. , XUE-FENG Z. , ANJUM S.A. , JI-XUAN S. , YAN Z. , YU-FENG D. , ZOHAIB A. , ALI I. , YU XU , XIU-JUAN H. , SAN-GEN W.
Published: July 2018

ABSTRACT: Plant growth regulators are an immense group of substances that have the ability to alter growth pattern of plants and can be used for improving plant growth and productivity. A study was conducted in the Xilin Gol grassland of Inner Mongolia, China, to ascertain the growth and biomass production of Stipa krylovii in response to exogenous application of different growth regulators at various concentrations viz. naphthalene acetic acid (NAA), 6-benzylaminopurine (6-BA), brassinosteroid (BR), sodium nitrophenolate (SNP) and forchlorfenuron, and gibberellic acid (GA3). Application of growth regulators significantly enhanced the growth and biomass production of S. krylovii. The height of vegetative shoot was enhanced mostly by the application of 100 mg L-1 GA3, while, height of reproductive shoot was increased by 25 mg L-1 6-BA, 100 mg L-1 SNP + 5 mg L-1 forchlorfenuron and 50 mg L-1 SNP + 2.5 mg L-1 forchlorfenuron as compared to control. Fresh biomass was enhanced by the application of 0.02 mg L-1 BR, 10 mg L-1 SNP + 0.5 mg L-1 forchlorfenuron and 50 mg L-1 SNP + 2.5 mg L-1 forchlorfenuron. Application of 5 mg L-1 6-BA and 50 mg L-1 SNP + 2.5 mg L-1 forchlorfenuron proved to be more beneficial in improving dry biomass of S. krylovii, as compared to control. In conclusion, exogenous application of different growth regulators improved growth and biomass production of S. krylovii. Furthermore, application of SNP + forchlorfenuron and 6-BA was more effective.
Longevity of Horseweed Seed Bank Depending on the Burial Depth
Authors: VARGAS A.A.M. , AGOSTINETTO D. , ZANDONÁ R.R. , FRAGA D.S. , AVILA NETO R.C.
Published: July 2018

ABSTRACT: Horseweed (Conyza spp.) is considered as one of the major weeds occurring in the agricultural areas of South America, especially in Brazil. This species stands out from the other weeds due to characteristics such as large seed production, continued seed production, dispersion over long distances and resistance to 5-enolpyruvoylshikimate 3-phosphate (EPSP) and acetolactate synthase (ALS) inhibiting herbicides, features that increase their management. Therefore, this study aimed at determining the physiological quality and longevity of horseweed seeds over 12 months. The experiment was established under field conditions, using a randomized block design with four replications. Fifty horseweed seeds were distributed into 50 g of dry soil, placed in permeable nylon mesh bags (10 x 10 cm), which were buried at 1, 2, 4 and 8 cm of depth. Each month, for 12 months, samples were collected and washed with water, and the remaining seeds were submitted to germination test. The percentage (%) of remaining seeds, germination, abnormal seedlings, dead seeds, dormancy and viability were evaluated. It was found that the horseweed seed bank was reduced by 59 % over 12 months. Moreover, horseweed seeds develop a secondary dormancy, regardless of the burial depth. In addition, an increased burial depth increases longevity and physiological seed quality.
Weed Management in Beans Using Subdoses of Fluazifop-P-Butyl + Fomesafen
Authors: GALON L. , CASTOLDI C.T. , FORTE C.T. , DE DAVID F.A. , PERIN G.F. , RADUNZ A.L.
Published: July 2018

ABSTRACT: The objective of this work was to evaluate the effect of reduced doses of the commercial mixture composed of fluazifop-p-butil + fomesafen, applied for the management of common weeds in beans. The experiment was conducted in a completely randomized block design, with a 5x2+1 factorial arrangement and with four replications. In factor A, there were five percentual doses (100, 87.5, 75.0, 62.5 and 0.0%), in relation to the recommended commercial dose (2 L ha-1) of fluazifop-p-butil + fomesafen, which corresponded to 2.00; 1.75; 1.50; 1.25 and 0.00 L ha-1. Factor B was composed by two development stages of black beans (three and eight trefoils) and weeds: black-jack (two to four and four to eight leaves) and southern crabgrass (two leaves to one tiller and one to four tillers) with one weeded control treatment. The variables evaluated for the control of black-jack and southern crabgrass were: herbicide phytotoxicity to the crop, number of pods per plant, number of grains per pod, 1,000 grain weight and grain yield of the crop. The results demonstrated that the use of fluazifop-p-butil + fomesafen, at all evaluated doses evaluated and application periods, caused low phytotoxicity to the crop, less than 12%. The use of reduced doses of this herbicide presents efficient control of black-jack and southern crabgrass, mainly at the initial development stages of these weed species. The economic threshold dosage of fluazifop-p-butil + fomesafen to control these weeds was 1.23 L ha-1.
Cross-Resistance to Imazapic and Imazapyr in a Weedy Rice (Oryza sativa) Biotype Found in Malaysia
Authors: DILIPKUMAR M. , BURGOS N.R. , CHUAH T.S. , ISMAIL S.
Published: July 2018

ABSTRACT: The Clearfield® rice production system is an effective management tool for weedy rice and other weeds in the direct-seeded rice culture. However, if farmers cultivating the Clearfield® rice disregard stewardship recommendations, the industry could face a problem of herbicide-resistant weedy rice which would occur through the selection of outcrosses. This study aimed to confirm imidazolinone-resistant weedy rice in Malaysia. The resistant weedy rice (R-WR) was found to be 67 fold more resistant to OnDuty® (premix of imazapic and imazapyr) than the susceptible weedy rice (S-WR) based on the GR50 values (rate that causes 50% inhibition of shoot growth). The Clearfield® rice cultivar was 32-fold more tolerant to OnDuty® than the S-WR. Furthermore, the R-WR was 54 and 89 fold more resistant to imazapic and imazapyr applied separately than the S-WR, respectively. The Clearfield® rice was 140- and 40-fold more tolerant to imazapic and imazapyr, respectively than the S-WR. The R-WR biotype was susceptible to non-selective herbicides glyphosate and glufosinate, as well as the selective graminicide quizalofop. Oxadiazon controlled the R-WR biotype, but pretilachlor was ineffective. The present study documented the first case of weedy rice that was cross-resistant to imazapic and imazapyr in Malaysian Clearfield® rice field.
Weed Management in Direct Seeded Rice Grown under Varying Tillage Systems and Alternate Water Regimes
Authors: RIAZ A. , KHALIQ A. , FIAZ S. , NOOR M.A. , NAWAZ M.M. , MAHBOOB W. , ULLAH S.
Published: July 2018

ABSTRACT: In direct seeded rice (DSR), flushes of weeds are encountered, and mostly subsequent herbicides need to apply to control weeds that appear later. A farmer friendly approach was hypothesized in present study to integrate the management strategies for water, soil and cost effective weed free rice production. Efficacy of various herbicides in weed control to improve the performance of aerobic rice grown under varying tillage and alternate water regimes was evaluated. Five weed management techniques (weedy check, weed-free, pendimethalin followed by manual weeding, pendimethalin + bispyribac sodium (BS) + bensulfuron (B) and pendimethalin + MCPA) were carried out within the alternate wetting and drying (AWD) regimes (15 and 20 cm depth) under two tillage systems (zero and conventional). All the herbicide treatments reduced the weed intensity as compared to weedy check, however minimum weed density and dry biomass was observed in pendimethalin at 40 and 60 days after sowing, respectively. Under conventional tillage, weed free plots showed maximum leaf area index, leaf area duration and crop growth rate. Maximum plant height, 1000-kernel weight and kernel per panicle along with less percentage of abortive, chalky and opaque kernels were recorded in pendimethalin followed by BS+B as compared to weedy check plots. Among the herbicides application, pendimethalin followed by BS+B gave highest benefit to cost ratio and net benefits under both AWD regimes. Overall, application of pendimethalin followed by BS+B is an efficient and economic approach to reduce weed infestation which results in improved yield of aerobic rice.
Weed Management with Urochloa ruziziensis in Three Sowing Methods
Authors: TIMOSSI P.C. , TEIXEIRA I.R. , LIMA S.F. , TELLES T.F.M.
Published: July 2018

ABSTRACT: This research aimed at investigating which sowing method is more suitable for the deployment of Urochloa ruziziensis to suppress the weed community in no-tillage. The design was a randomized block ones, with a 3 x 2 factorial design, in which the first factor was composed of three sowing methods (broadcast, broadcast with incorporation or line sowing) and factor B consisted in the application and non-application of the herbicide 2,4-D. On day 30 and 60 after sowing (DAS), the relative importance of the present plant species was determined. On day 120 and 180 DAS, the accumulation of biomass and the plant cover percentage on the soil provided by the cover crop and weed species were determined. Moreover, on day 180 DAS, the density of the existing weeds was determined. The weed with the highest occurrence in the area was Conyza canadenses, and the lowest percentage of soil covering by signalgrass and the greates occurrence of weeds occurred with broadcast seeding. It is possible to conclude that the broadcast seeding with the incorporation of signalgrass seeds and line sowing methods provide enough plant cover to suppress weed species, avoiding the application of the herbicide 2,4-D in order to suppress the infesting community.