bluuebunny/crossref_metadata_2025 huggingface dataset:
Organizational and technological platform of construction
Authors: Lapidus Azariy A.
Published: May 2022

Introduction. At present, due to the active introduction of digital technologies, technological platforms are actively developing, the purpose of which is the implementation of various products. The presented study considers the organizational and technological platform of large-scale construction projects — a set of material and labor resources, organizational and technological solutions that allow, through their interaction, using modern information modeling technologies, to create construction objects with specified technical and economic characteristics.

Materials and methods. For the formation of the organizational and technological platform, the methods of the goal tree and the analysis of hierarchies are used. A decomposition of a complex system is presented, presented at three levels of the goal tree and described using the analysis of hierarchies. At the top level, the goal of the project, followed by the problem (task), and at the last, lower level of the tree of goals are directions for solutions.

Results. For the most adequate analytical description, it is proposed to use the hierarchy analysis method, which makes it possible to decompose the above factors that make up the goal tree and obtain specific criteria and alternatives inherent in large-scale construction projects, based on the principle of smart criteria formation. The creation of a mathematical model of an organizational and technological platform should be carried out using the possibility of constructing priority weight vectors that take into account the significance of all criteria, and each criterion is weighted based on these data. The integral assessment of indicators weighted for each criterion can be the final weight in the criterion structure. Detailed development of the mathematical apparatus for obtaining an integral estimate will be the subject of further research.

Conclusions. The organizational and technological platform of large-scale projects in construction is a tool for the interaction of all participants in the implementation of such projects, aimed at the successful implementation of the set goals — achieving design indicators in terms of duration.
Sentidos de ‘normal’/’anormal’ em circulação: o diferente como caução argumentativa
Authors: Moura Júnior Gildo Antonio , Agustini Cármen
Published: May 2022

Neste artigo, filiados à Semântica do Acontecimento, elaborada por Eduardo Guimarães (2002; 2005; 2018), que considera que os sentidos são constituídos no enunciado, na relação de uma palavra com outra, analisamos a designação das palavras ‘normal’/‘anormal’ em um arquivo constituído por nove textos midiáticos de circulação no Brasil, publicados no período de 2000 a 2019, nos quais as palavras ‘normal’/‘anormal’ constam de suas formulações. O interesse de reflexão sobre o par de palavras (‘normal’/‘anormal’) encontra-se em compreender como os seus sentidos se constituem nos enunciados nos quais elas comparecem como qualitativo de ser humano, e de que forma esses sentidos dialogam com a historicidade dos sentidos de ‘normalidade’. Os sentidos de tais palavras têm ganhado o cotidiano do brasileiro para designar diversas práticas, comportamentos, ideias, ações etc. Portanto, investigamos como o ‘normal’/‘anormal’ significa e faz significar o diferente como caução argumentativa de certas práticas segregacionistas. Essa análise mostra como o político atravessa a língua no acontecimento da enunciação, fazendo significar uma divisão desigual do real, na qual os sentidos de ‘normal’ caucionam argumentativamente essa divisão. Essa divisão funciona determinando como o enunciado pode e deve incluir certos sentidos e excluir outros. É assim que um enunciado concorre por espaço com outro(s) enunciado(s), instaurando uma disputa por significar. Em decorrência da constituição política do enunciado, analisamos a historicidade da palavra ‘normal’/’anormal’, para compreender de que forma sua significação é interpelada por questões políticas de poder dizer.
Post-Tradisionalisme: Membincang Basis Epistemologi dan Transformasi Gerakan Moderasi Beragama Nahdlatul Ulama
Authors: Bindaniji Muhamad , Fuadi Moh Ashif
Published: May 2022

Islamic post-traditionalism is one of the discourses of Islamic thought that is developing in Indonesia. It emerged from the historical development of Islamic thought in Indonesia that continues to grow to find a  compatible and comprehensive format of Islam that is relevant to the problem faced by the Muslim Community. This study aims to explain the development of post-traditionalism discourse and its epistemology and the transformation of the religious moderation movement among the Nahdhatul Ulama organization. This study uses a literature study consisting of books, articles, and other relevant sources. Through a sociological-historical approach, this study concludes that post-traditionalism within Nahdlatul Ulama (NU) is not a modernist group seen from its movement and characteristics of its thoughts because they still adhere to salaf traditions. In addition, through cultural movements, Nahdlatul Ulama plays a very important role in internalizing wasathiyah through the acceptance of madzhab, Asy'ariyah creed, integration of Islam into nationality, and interfaith dialogue movements. Abstrak: Wacana post-tradisionalismeisme Islam adalah sebuah produk pemikiran yang terbingkai dalam korpus wacana pemikiran Islam yang berkembang di Indonesia. Sebagai sebuah produk pemikiran, post-tradisionalismeisme sejatinya terlahir dari perkembangan sejarah pembentukan wacana pemikiran Islam di Indonesia yang terus berdialektika sambil menemukan bentuk atau format yang kompatibel dan komprehensif dengan perkembangan zaman. Adapun bentuk dialektika tersebut dapat tercermin melalui pergulatan ‘tradisi’ yang menghasilkan istilah post-tradisionalismeisme, dalam hal ini Nahdlatul Ulama (NU), melalui persentuhan dengan pemikiran atau realitas lain di luar tradisi asal NU. Penelitian ini menggunakan studi literatur baik melalui buku, artikel jurnal, dan berbagai sumber relevan lainnya. Melalui pendekatan sosiologis-historis, penelitian ini menyimpulkan bahwa post-tradisionalismeisme dalam tubuh NU bukanlah kelompok modernis baik dari sisi gerakan maupun corak pemikiran, karena masih berpegang teguh terhadap tradisi-tradisi salaf, hanya saja kalangan post-tradisionalismeisme memberikan pemahaman yang lebih mendalam dan radikal melampaui tradisi itu sendiri. Selain itu, melalui gerakan kultural yang dipelopori Gus Dur, NU sangat berperan dalam menginternalisasikan wasathiyah melalui penerimaan mazhab, Aqidah Asy’ariyah, integrasi keislaman dengan kebangsaan, dan gerakan dialog antar agama.
Exploring taboos through Socially Oriented Design
Authors: Yann Charles M Bougaran-Faivre d'Arcier
Published: May 2022

Visualising taboos and societal issues.

For the last 5 years we've been investigating the possibilities to inform and communicate several societal issues and taboos such as loneliness, mental issues related problems and failure.

S.O.D. has been working with students, graphic designers and teachers in Russia, England, France, Norway, Finland and South Korea to investigate these problems within an international framework.

S.O.D.’s primary goal is to communicate. Based on the fact that graphic design is one of the best tools available to do so, I am constantly reminding our members to develop their ideas and to design in order to reach our goal, not to win awards. Graphic design is not a sport, but a set of tools and skills that allow us to do a specific work to solve a specific problem.
This approach is in line with the general understanding of design and its difference from art: in the Design: Creation of Artifacts in Society, it is understood as an activity where a gap is first defined and a solution is proposed, prototyped and developed. In the case of S.O.D the gap is a lack of attention to the problems of societal issues and taboos, and the design process focuses on developing solutions that could affect these issues in a positive way.

Our work can be seen as a non commercial use of Graphic Design, tending to communicate based on emotional responses from the audience instead of consumer's needs.

These projects have been a stepping-stone towards future investigations of societal or cultural themes may be put under a new light by using the means of S.O.D. By exposing societal issues as something different than an individualized fiasco. Perhaps S.O.D will make a small, but significant gesture of emancipation to those who feel the need to share their thoughts and make a change.
The calcium sensor CBL7 is required for Serendipita indica -induced growth stimulation in Arabidopsis thaliana, controlling defense against the endophyte and K + homeostasis in the symbiosis
Authors: Pérez-Alonso Marta-Marina , Guerrero-Galán Carmen , Ortega-Villaizán Adrián González , Ortiz-García Paloma , Scholz Sandra , Sakakibara Hitoshi , Kiba Takatoshi , Ludwig-Müller Jutta , Krapp Anne , Oelmüller Ralf , Vicente-Carbajosa Jesús , Pollmann Stephan , Ramos Patricio
Published: May 2022

Calcium (Ca ) is an important second messenger in
plants. The activation of Ca signaling cascades is
critical in the activation of adaptive processes in response to
perceived environmental stimuli, including biotic stresses. The
colonization of roots by the plant growth promoting endophyte
Serendipita indica involves the increase of cytosolic Ca
levels in Arabidopsis thaliana. In this
study, we investigated transcriptional changes in Arabidopsis roots
during symbiosis with S. indica. RNA-seq profiling disclosed the
significant induction of CALCINEURIN B-LIKE 7 ( CBL7)
during early- and later phases of the interaction. Consistent with the
transcriptomics analysis, reverse genetic evidence and yeast two-hybrid
studies highlighted the functional relevance of CBL7 and tested the
involvement of a CBL7-CBL-INTERACTING PROTEIN KINASE 13 (CIPK13)
signaling pathway in the establishment of the mutualistic relationship
that promotes plant growth. The loss-of-function of CBL7
abolished the growth promoting effect of S. indica and affected
the colonization of the root by the fungus. The subsequent
transcriptomics analysis of cbl7 revealed the involvement of this
Ca sensor in activating plant defense responses.
Furthermore, we report on the contribution of CBL7 to potassium
transport in Arabidopsis. Triggered by the differential expression of a
small number of K channels/transporter genes, we
analyzed K contents in wild-type and cbl7
plants and observed a significant accumulation of K
in root of cbl7 plants, while shoot tissues demonstrated K
depletion. Taken together, our work associates CBL7
with an important role in the mutual interaction between Arabidopsis and
S. indica and links the CBL7 Ca receptor
protein to K transport.
Life on a beach for island lizards: phenotypic divergence in the face of gene flow
Authors: Brown Richard , Jin Yuanting , Thomas Jordan , Meloro Carlo
Published: May 2022

Morphological divergence under gene flow was investigated in the wall
lizard Teira dugesii from the Atlantic island of Madeira island.
Lizards (n=334) were sampled using a matched pairs design at four
distinct coastal localities. Matched pairs comprised adjacent
(<1 km) grey shingle beach and inland sites. Luminances of
specific dorsal areas were recorded for each RGB channel from digital
photographs taken in the field. Lizards were found to be significantly
darker at beach sites than inland sites. Geometric morphometric analyses
using 35 landmarks placed on dorsal photographs of the head revealed
significant divergence between beach/inland habitats: wider snouts were
found at beach sites. Genotyping-by-sequencing of 93 individuals
provided 19311 cross-genomic SNPs. A spatial principal components
analysis showed significant genomic divergence across the four sampled
localities and within these localities. However, there was no evidence
that beach and inland populations formed distinct lineages. Patterns of
genomic divergence were compared with those generated from simulations
under three models. Primary findings were repeated across all four
localities. The model of divergence without gene flow was rejected,
while the most strongly supported model incorporating two periods of
gene flow: an early period of lower gene flow followed by a period of
higher gene flow. Gene flow from inland to beach was greater than that
in the opposite direction. This study demonstrates ecologically
significant morphological divergence in the face of gene flow and adds
to understanding of how divergence and speciation may occur within small
islands.
Defining the Distance Between the His Bundle and First Septal Perforator: Implications for Left Bundle Branch Pacing
Authors: Bocchese Matthew , Gannon Michael , Patil Pravin , Decker William Van , Whitman Isaac , Cronin Edmond
Published: May 2022

Introduction: Left bundle branch pacing (LBBP) is a developing
method of native conduction pacing, but cases of injury to the septal
perforator arteries during implantation have been reported. Knowing the
distance between the His bundle and the first septal perforator artery
can help operators implant LBBP leads more safely Methods:
Using previously performed coronary CT angiography (CCTA) studies, the
distance between the His bundle and the first septal perforator was
measured. Results: A total of 50 CCTA studies were included.
The mean distance from the His bundle to the first septal perforator
(His-SP) along the line connecting the His bundle to the RV apex (His-RV
apex) was 27.17 ± 7.7 mm with a range of 13.0 to 44.7 mm. The distance
was greater than 2.0 cm in 90% of patients. To standardize this
distance among patients with varying cardiac structures, the ratio
between the His-SP distance and the His-RV Apex distance was also
measured. The mean His-SP:His-RV Apex was 0.302 and the median was
0.298. 86% of patients had a ratio of greater than 0.20.
Conclusion: Using this information, operators can aim to
implant LBBP leads within 2.0 cm of the His bundle or 20% of the
distance between the His bundle and the RV apex with minimal risk of
causing vascular injury.
Existence and uniqueness of solutions of differential equations with respect to non-additive measures
Authors: Negi Shekhar , Torra Vicenc
Published: May 2022

By taking Sugeno-derivative into account, firstly, we investigate the
existence of solutions to the initial value problems (IVP) of
first-order differential equations with respect to non-additive measure
(more precisely, distorted Lebesgue measure). It particularly occurs in
the mathematical modeling of biology. We begin by expressing the
differential equation in terms of ordinary derivative and the derivative
with respect to the distorted Lebesgue measure. Then, by using the fixed
point theorem on cones, we construct an operator and prove the existence
of positive increasing solutions on cones in semi-order Banach spaces.
In addition, we also use Picard’s-Lindel\”of theorem to
prove the existence and uniqueness of the solution of the equation.
Second, we investigate the existence of a solution to the boundary value
problem (BVP) on cones with integral boundary conditions of a mix-order
differential equation with respect to non-additive measures. Moreover,
the Krasnoselskii fixed point theorem is also applied to both BVP and
IVP and obtains at least one positive increasing solution. Examples with
graphs are provided to validate the results.
Words and how we use them -- which is to be the master?
Authors: Anderson Robert , Spicer Diane E. , Quintessenza James , Najm Hani , Tretter Justin
Published: May 2022

This is an invited commentary and does not need a commentary.
Omission of adverse event reporting on finerenone
Authors: Brezis Mayer
Published: May 2022

We wish to describe the omission of adverse event reporting on
finerenone in a recently published trial. We suspect that this case
illustrates the tip of an iceberg of underreporting of adverse events in
clinical trials. We propose as a requirement in clinical trials, to have
routine direct reporting by patients for safety monitoring.
Grass functional traits respond differently to soil vs. atmospheric drought conditions
Authors: Watson Samantha , Aguirre Breatriz , Wright Alexandra
Published: May 2022

Climate change alters global mean surface temperatures and precipitation
regimes. This changes the composition and diversity of grasslands
worldwide. To date, there are no assessments of plant functional trait
responses to experimentally controlled atmospheric drought (separate
from soil drought). We examined whether soil and atmospheric drought
result in changes to Poa secunda functional traits in monoculture and
8-species grass communities. We focused on SLA, leaf area, stomatal
density, root:shoot ratio, and fine root:coarse root ratios. Leaf area
and overall growth were higher with increased watering and higher
atmospheric moisture in most cases. However, root:shoot ratio
significantly increased in atmospheric drought combined with drought
watering. Plant energy allocation strategy (measured using PCA) differed
when P. secunda was grown in combination soil and atmospheric drought
conditions. Our results indicate that methods focused purely on soil
water inputs, such as rainout shelters, may be imprecisely predicting
drought effects.
CD44v6+ hepatocellular carcinoma cells maintain cell stemness through the Met/cjun/Nanog signaling pathway
Authors: Chen Wei , Wang Ronghua , Zhao Yuchong , Li Yawen , Wang Xiju , Peng Wang , Bai Shuya , Zheng Mengli , Liu Man , Cheng Bin
Published: May 2022

Background and Purpose: Cancer stem cells (CSCs) are a type of cancer
cell owning the characteristic of self-renew and differentiation.We
hypothesize that the stemness properties in CD44v6+ hepatocellular
carcinoma cells (HCC) is promoted via the Met/cjun/Nanog signaling
pathway, thus, serves as a valuable target for HCC therapy. Experimental
Approach: We use lentiviral shMet and selective Met inhibitor PHA665752
to explore the function of Met/cjun/Nanog axi in CD44v6+ cells. The
orthotopic liver xenograft tumor model was used to detect self-renewal
ability of CD44v6+ cells. Furthermore, a luciferase reporter assay and
chromatin immunoprecipitation (ChIP) assay were carried out to find the
exact binding site of cjun in the Nanog promoter. Key Results: In this
study, we demonstrated that CD44v6+ CSCs not only facilitate the
properties of cancer stemness, but also represent the high expression of
the HGF/MET signal pathway. Inhibiting the activation of Met in CD44v6+
HCC cells in vidvo and in vitro significantly decrease the expression of
cjun and Nanog. Furthermore, we found a binding site of cjun in 1700bp
before the transcription start site of Nanog. Conclusion and
Implications: The stemness properties of CD44v6+ cells is promoted by
the Met/cjun/Nanog signaling pathway. And the cjun is binding in 1700bp
before the transcription start site of Nanog. KEYWORDS：Hepatocellular
Carcinoma, Cancer Stem Cells, HGF/MET, CD44v6, cjun
Teaching, researching and living in the field: the challenges of applied ethnography as education.
Authors: Aris Anagnostopoulos, Eleni Stefanou, Evangelos Kyriakidis
Published: May 2022

Every summer for the past four years, a small group of Greek and foreign students gather at the mountainous village of Gonies Malevyziou in central Crete to participate in the monthly International Field School “Engaging Local Communities in Heritage Management through Archaeological Ethnography”, organized by the Heritage Management Organization and the Cultural Association of Gonies. Teaching ethnography to non-anthropologists in the field is a challenging process as it brings to the fore multiple and interchanging roles for teachers and students alike. In this process of collective ethnographic learning, where the teaching setting is also our living setting and research setting, we often wonder about the entangled roles in the production of knowledge and interpretations articulated through theoretical readings, daily chores and lived experience. The demands of active research running side by side to methodological instruction and teaching create different expectations that shape the learning experience in unpredictable ways. This paper discusses some of the issues involved in this process: What is the position of members of the local community as producers, instigators and transmitters of this knowledge? How are our multiple identities as teachers, researchers, friends, visitors, locals/non-locals articulated within and outside the field? Finally, how is the knowledge produced managed and controlled by the community and the people responsible for the summer school?
O CONTO “ÓTIMA É A ÁGUA” DE PRIMO LEVI, COMO MOTE PARA O ESTUDO E COMPREENSÃO DO CONCEITO DE VISCOSIDADE
Authors: Gasparetto Fábio Eduardo de Assis , Cedran Débora Piai , Sá Marilde Beatriz Zorzi
Published: May 2022

Este artigo apresenta resultados de uma pesquisa de natureza qualitativa realizada com estudantes do Ensino Médio de uma Escola Pública da cidade de Maringá-PR, com o objetivo de responder à pergunta: que potencialidades pedagógicas, na aprendizagem do conceito de viscosidade, são reveladas pelo conto “Ótima é a água”? Analisando, desta forma, as contribuições do referido conto de Primo Levi para os processos de ensino e de aprendizagem. Para tanto, utilizou-se o conto, questionamentos constituídos por questões abertas e um experimento de caráter investigativo que se configuraram em instrumentos de coleta de dados. O estudo possibilitou discussões significativas a respeito da utilização e contribuições do conto empregado como ferramenta problematizadora para a construção de conhecimentos. Entre as discussões, destaca-se a importância de metodologias que possibilitem reflexões acerca de concepções dos estudantes, como a de que os conceitos de viscosidade e densidade são similares. Além disso, reflexões sobre problemas ambientais e o próprio conceito de viscosidade foram pontos significativos apontados na pesquisa.
FUNÇÕES EPISTÊMICAS DE MODELOS NO PROCESSO DE ENSINO E APRENDIZAGEM EM CITOGENÉTICA: UMA ANÁLISE NO CONTEXTO DA FORMAÇÃO INICIAL DE PROFESSORES DE BIOLOGIA
Authors: Cardoso Mendonça Paula Cristina , Cláudio Denise Suzane De Oliveira , Franco Luiz Gustavo
Published: May 2022

Nesta pesquisa, analisamos como professores de Biologia em formação inicial mobilizam funções epistêmicas de modelos nos processos de ensino e aprendizagem em citogenética. Coletamos dados de interações de um grupo de licenciandos em uma sequência didática sobre divisão celular que envolveu a prática de modelagem. Para análise, transcrevemos situações com maior potencialidade analítica, organizadas em cenas e episódios de ensino. Os resultados indicam que os licenciandos mobilizaram diferentes funções epistêmicas dos modelos em discussão: (i) representar, no sentido de similaridade e no sentido de estar no lugar; (ii) investigar e prever; (iii) comunicar; (iv) dar suporte a argumentos e explicações científicas; (v) simplificar e (vi) disponibilizar uma imagem conceitual. Funções epistêmicas relacionadas à comunicação de ideias e argumentação ampliaram oportunidades para que dúvidas de caráter conceitual e/ou visões distorcidas de alguns conceitos emergissem nas interações. Além disso, o estudo aponta implicações para a formação de professores e o ensino de Biologia, especialmente no que diz respeito ao uso da modelagem não apenas como uma atividade de mera manipulação ou representação, mas como uma oportunidade para refletir sobre modelos como artefatos epistêmicos ao possibilitar a vivência mais autêntica da prática científica em contextos de ensino.
QUAL CIÊNCIA É NEGADA NAS REDES SOCIAIS? REFLEXÕES DE UMA PESQUISA ETNOGRÁFICA EM UMA COMUNIDADE VIRTUAL NEGACIONISTA
Authors: Fasolo Pivaro Gabriela , Girotto Jr Gildo
Published: May 2022

Considerando o contexto histórico da pós-verdade no qual nos inserimos, que possui como uma de suas características movimentos de ataque à credibilidade da ciência inflados em redes sociais por motivações políticas de líderes extremistas, buscamos nessa pesquisa analisar como esse discurso pode influenciar as concepções sobre a construção do conhecimento científico dos usuários das redes sociais digitais. Realizamos uma etnografia no Twitter, acompanhando uma comunidade de usuários comumente associada ao negacionismo, contendo o presidente brasileiro Jair Bolsonaro e seus aliados. Encontramos quatro categorias de discurso dos usuários, que denominamos: a ciência versus “ciência”; uma correlação egocentrada de variáveis; um pedido excessivo de fontes; e para além da crença imediata. Essas categorias mostram concepções que envolvem a ideia da existência de uma ciência neutra, a construção de uma forma de conhecimento que não busca estruturar generalizações e uma ausência de análise crítica própria do usuário. Defendemos que compreender como o ataque à ciência é propagado nas redes sociais e como os discursos negacionistas influenciam as concepções sobre ciência e construção do conhecimento científico é essencial para se pensar em estratégias específicas de letramento científico e, deste modo, trazemos argumentos e reflexões sobre tais aspectos no contexto da pós-verdade frente ao combate à proliferação massiva de desinformação nas redes.
ETNOBOTÂNICA NAS PESQUISAS EM ENSINO E SEU POTENCIAL PEDAGÓGICO: SABER O QUÊ? SABER DE QUEM? SABER POR QUE? SABER COMO?
Authors: Rebello Thiago José Jesus , De Meirelles Rosane Moreira Silva
Published: May 2022

A pesquisa etnobotânica revela saberes gerados na interação entre grupos socioculturais e a diversidade vegetal do território. No campo educacional, estudos indicam que esse conhecimento etnobotânico pode colaborar com a formação dos estudantes. Visando amplificar tal potencial pedagógico, este trabalho teve o objetivo de identificar categorias que revelem de que modo a pesquisa em Ensino aborda o conhecimento etnobotânico. Para isso, realizou-se pesquisa de “estado da arte”, tendo como tema o saber popular sobre plantas e como base de análise as publicações das edições de três eventos da área de pesquisa em Ensino - ENEBIO, EPEA, ENPEC - realizadas de 1997 até 2020. Foram selecionados 136 trabalhos, representando 1,10% da produção total dos eventos. A análise dos dados ocorreu a partir de quatro descritores: saber etnobotânico abordado; grupo produtor do saber; justificativa para inclusão do saber etnobotânico; inserção do saber etnobotânico. Os resultados revelaram a predominância do conhecimento sobre o potencial medicinal das plantas e sobre o cultivo e manejo de espécies alimentícias. Os saberes abordados, em geral, pertenciam a grupos étnicos, regionais e rurais. Dentre as razões para inserir conhecimento etnobotânico no ensino, destacaram-se benefícios culturais, pedagógicos e ambientais. Levantamento de saberes populares e proposição de sequências didáticas foram as maneiras mais frequentes de inserir o conhecimento etnobotânico nas pesquisas. Concluiu-se que o conhecimento etnobotânico apresenta potencial para uma educação multicultural, mas que se deve atentar para o risco da abordagem utilitária desses saberes.
Retraction: Fan X, Tanomtong A, Chaveerach A, Pinthong K, Pornnarong S, Supiwong W, Liehr T, Weise A. High resolution karyotype of Thai crab-eating macaque (Macaca fascicularis). Arch Biol Sci. 2014;66(4):1603-7. Doi: 10.2298/ABS1404603F
Authors: Editorial E
Published: May 2022

This is a notice of retraction of the article: High resolution karyotype of
Thai crab-eating macaque (Macaca fascicularis) by Xiaobo Fan, Alongkoad
Tanomtong, Arunrat Chaveerach, Krit Pinthong, Siripiyasing Pornnarong,
Weerayuth Supiwong, Thomas Liehr, and Anja Weise, published in: Archives of
Biological Sciences in 2014, Vol. 66, Issue 4:
https://doi.org/10.2298/ABS1404603F. The Editor-in-Chief has been informed
that this paper is a duplicate of the paper: High resolution karyotype of
Thai crab-eating macaque (Macaca fascicularis) by Xiaobo Fan, Alongkoad
Tanomtong, Arunrat Chaveerach, Krit Pinthong, Siripiyasing Pornnarong,
Weerayuth Supiwong, Thomas Liehr, Anja Weise, published in: Genetika, Vol.
46, No. 3, 877- 882, 2014: https://doi.org/10.2298/GENSR1403877F. This claim
is correct and the entire paper is a verbatim copy of the earlier one. After
confirmation of this fact, the Editor-in-Chief of the Archives of Biological
Sciences has decided to retract the paper immediately. We apologize to the
readers of the journal that it took so many years to notice this error and
to retract the paper. We request readers of the journal to directly get in
touch with the editorial office and the editors of the journal for similar
cases in the future so that they can be handled promptly.

 Link to the retracted article 10.2298/ABS1404603F
COVID-19 Vaccination Safety in Patients who have had SARS-CoV-2-induced Chilblains
Authors: Poizeau Florence , Triquet Louise , Dupuy Alain
Published: May 2022

Abstract is missing (Short communication)
Mal de Meleda: Diagnostic Work-up and Therapy with Low-dose Acitretin
Authors: Pospischil Isabella , Enzelsberger Klaus , Gross Susanne , Hoetzenecker Wolfram , Fischer Tobias W.
Published: May 2022

Abstract is missing (Short communication)
Effect of Cervical Lesions on Fracture Resistance and Failure Mode of Maxillary Central Incisors Restored with Fiber Posts and Complete Crowns
Authors: Santos Pantaleón D , Valenzuela FM , Morrow BR , Pameijer CH , García-Godoy F
Published: May 2022

Purpose

To investigate the effect of a cervical cavity extending 1 mm apical to the cemento–enamel junction (CEJ) on fracture resistance and failure mode of maxillary central incisors that have been treated endodontically, present with complete and incomplete ferrules, and are restored with and without a fiber post.

Methods and Materials

50 intact human maxillary central incisors were divided into five groups (n=10): CG (control group) 6-mm fer-rule height, no cervical cavity, and without post; (CO) 6-mm ferrule height without post, with a cervical cavity (access to root canal and cervical cavity restored with composite resin), cervical cavity; and post with ferrule heights of 1 mm (CP1), 2 mm (CP2), and 6 mm (CP6) restored with fiberglass post and composite resin core. After complete metal crowns were cemented on all specimens, they were subjected to thermal cycling (6000 cycles, 5°C/55°C), followed by immediate testing of fracture resistance. After failure, the specimens were sectioned buccolingually to evaluate and identify the mode of failure. The data were analyzed with an analysis of variance (ANOVA) and the Student–Newman–Keuls multiple comparison tests (α =0.05).

Results

A 1-mm ferrule height (CP1) fracture resistance was significantly lower (531±125 N) compared to the 6-mm ferrule height (CP6) (769±175 N) (p<0.05). With respect to the groups with similar residual dentin, with and without a cervical cavity, CG (667±119 N) and CO (668±119 N), the presence of a post (CP6) increased the resistance to fracture, although no statistically significant difference was demonstrated. Partial decementation was observed in all specimens of CG and CP6, in nine of CP1 and CP2, and in three in CO. Root fractures occurred in 23 specimens. The root surface was exposed 2 mm below the CEJ to simulate bone level. Propagation of subosseous cracks occurred in four specimens in CG and CP2, in seven specimens in CP6, in two specimens in CP1, and in six specimens in CO. All were considered catastrophic failures.

Conclusions

Within the limitations of this study it is suggested that, when restoring an endodontically treated maxillary central incisor that has a cervical lesion and needs to be restored with a complete crown, a fiber post is cemented to improve fracture resistance.
Color Match of Composite Resin and Remaining Tooth Structure over a Period of 28 Days Using Spectrophotometer—A Randomized Clinical Trial
Authors: Hashir MMJ , Ravishankar P , Dhanapal S , PradeepKumar AR
Published: May 2022

OBJECTIVES

The tooth and the composite restoration can undergo a change in color after the restorative procedure over time. The purpose of this randomized clinical trial was to evaluate the color difference (ΔE) of two types of composite resins and remaining tooth structure over a period of 28 days.

METHODS AND MATERIALS

A total of 40 teeth in 30 patients with Class IV caries or EllisClass II fracture in maxillary incisors were randomized into two groups based on the type of composite resin used for restoration: IPS Empress (n=20 teeth) and Filtek Z250 (n=20 teeth). Shade selection was done using a spectrophotometer. Restorations were performed using an anatomical layering technique, and finishing and polishing was done after 48 hours. Baseline spectrophotometer color values for the remaining tooth structure were measured before isolation and for composite restorations, 10 minutes after light cure. Further color evaluations using a spectrophotometer for the remaining tooth structure and composite restorations were done at 48 hours (both before and immediately after finishing and polishing), 7days, 14 days, and 28 days, and color difference (ΔE) from baseline values for remaining tooth structure and restorations and ΔE between remaining tooth structure and restorations were calculated. Descriptive statistics including mean, standard deviation, and frequencies were computed. Mann–Whitney U test was done to compare spectrophotometer values.

RESULTS

There was a significant reduction in mean color difference (ΔE) from baseline values for both tooth (p<0.05) and composite restoration (p<0.05) at all evaluation periods in both groups. Filtek Z250 showed significantly lower mean ΔE between the tooth and the composite resin restoration than IPS Empress at 48 hours (before and after finishing and polishing), 7 days and 14 days (p<0.05). At the 28 day recall, mean ΔE value of IPS Empress restorations to tooth structure was 3.5, while the mean ΔE value of Filtek Z250 restorations to tooth structure was 3.6, which was not statistically different (p>0.05).

CONCLUSION

The remaining tooth structure as well as the composite restorations showed color changes at all evaluation periods, compared to baseline values in both the composite resin groups. Filtek Z250 exhibited less ΔE with remaining tooth structure at 48 hours, 7 days, and 14 days, when compared to IPS Empress. The composite restorations of both the groups reached clinically acceptable color match (mean ΔE<3.7) with the remaining tooth structure 28 days after the procedure.
A multicenter, randomized, open-label, comparative, phase IV study to evaluate the efficacy and safety of combined treatment with mycophenolate mofetil and corticosteroids in advanced immunoglobulin A nephropathy
Authors: Han Sang Youb , Jung Chan-Young , Lee Sang Ho , Lee Dong Won , Lee Sik , Kim Chan-Duck , Choi Bum Soon , Kim Beom Seok
Published: May 2022

Background: It remains unclear whether immunosuppressive agents are effective in patients with immunoglobulin A nephropathy (IgAN). We investigated the efficacy of a mycophenolate mofetil (MMF) and corticosteroid combination therapy in patients with advanced IgAN. Methods: We conducted a multicenter, randomized, placebo-controlled, parallel-group study of 48 weeks administration of MMF and corticosteroids in biopsy-proven advanced IgAN patients with estimated glomerular filtration rate (eGFR) of 20–50 mL/min/1.73 m2 and urine protein-to-creatinine ratio (UPCR) of >0.75 g/day. The primary outcome was complete (UPCR < 0.3 g/day) or partial (>50% reduction of UPCR compared to baseline) remission at 48 weeks. Results: Among the 48 randomized patients, the percentage that achieved complete or partial remission was greater in the combination therapy group than in the control group (4.2% vs. 0% and 29.1% vs. 5.0%, respectively). Compared with the combination therapy group, eGFR in the control group decreased significantly from week 36 onward, resulting in a final adjusted mean change of –4.39 ± 1.22 mL/min/1.73 m2 (p = 0.002). The adjusted mean changes after 48 weeks were 0.62 ± 1.30 and –5.11 ± 1.30 mL/min/1.73 m2 (p = 0.005) in the treatment and control groups, respectively. The UPCR was significantly different between the two groups; the adjusted mean difference was –0.47 ± 0.17 mg/mgCr and 0.07 ± 0.17 mg/mgCr in the treatment and control group, respectively (p = 0.04). Overall adverse events did not differ between the groups. Conclusion: In advanced IgAN patients with a high risk for disease progression, combined MMF and corticosteroid therapy appears to be beneficial in reducing proteinuria and preserving renal function.
Two decades of hybrid electric vehicle market
Authors: Menes Maciej
Published: May 2022

The article presents a cross-sectional view of the development of the HEV car market over the last two decades. Hybrid cars are currently the widest group of cars equipped with alternative to classic drive systems. They are also the most numerous group among electric vehicles. The historical meanders of HEV development were described, as well as the current level of development of this market and the real prospects for the popularization of HEV cars. The level of world production of this category of motor vehicles in the twenty-year period 2001-2020 was also characterized. The article attempts to estimate the real size of the world\'s HEV fleet. The level of sales of this category of vehicles by individual countries and their changing percentage share in the passenger car market were also presented. Sales of electric hybrids even in the crisis year 2020 increased from 3.2 million to approx. 4 million vehicles, despite a decrease in sales of new passenger cars from 64 to 54 million units. The above fact also proves the market attractiveness of this type of vehicles and the constantly growing interest in them.
técnica de julgamento ampliado à luz do princípio do contraditório
Authors: Korczagin Mansur , Toporoski Elizeu Luiz
Published: May 2022

A presente pesquisa busca analisar a observância dos princípios constitucionais, principalmente do contraditório, pela técnica de julgamento ampliado, seguindo o método indutivo, com análise bibliográfica. Referida técnica aplica-se nos recursos de apelação, ação rescisória e no agravo de instrumento, mas não se aplica aos incidentes de assunção de competência e ao de resolução de demandas repetitivas, além da remessa necessária e nos julgamentos proferidos pelo plenário ou corte-especial. Portanto, a aplicação da técnica e a garantia da sustentação oral vai depender do regimento interno de cada tribunal, desde que observe os princípios constitucionais. Assim, de modo a evitar discussões sobre violações dos princípios constitucionais, em especial do contraditório, deve-se sempre garantir às partes e a eventuais terceiros a possibilidade da realização de sustentação oral, com o objetivo de influenciar os julgadores a proferirem uma decisão imparcial.
Violência contra a mulher
Authors: Arruda Laíza , Bueno Mariza Schuster
Published: May 2022

O presente artigo objetiva conceituar direitos fundamentais e direitos das mulheres, verificar questões voltadas à pandemia, bem como pretende descrever a violência contra a mulher no Brasil e analisar o aumento de casos e a diminuição das denúncias durante o isolamento social imposto pelo COVID-19. Utiliza-se no presente trabalho, de pesquisa qualitativa através do método dedutivo, com fundamento na legislação brasileira, especialmente a Lei Maria da Penha n. 11.340/06, doutrina com o propósito de conceituar os tipos de violência contra a mulher existentes no ordenamento jurídico brasileiro e especificar suas diferenças. A pandemia imposta pela COVID-19 é um fator significativo a ser estudado em razão do isolamento social ocorrido nos anos de 2020 e 2021, e o aumento dos casos de violência contra a mulher e a diminuição das denúncias, em razão de que as vítimas convivem com seus agressores continuamente. Por fim, busca-se responder o questionamento: Houve um aumento de casos de violência doméstica contra a mulher durante a pandemia do COVID-19? Com esse aumento, houve uma queda em denúncias realizadas? Através da análise de dados registrados no último ano, percebe-se que enquanto os casos de violência doméstica aumentaram, as denúncias em delegacias diminuíram, principalmente em razão da necessidade de o inquérito ser instaurado com a presença da vítima.
tensão entre o acordo de não persecução penal e o estado de inocência
Authors: Telles Cristiane Mara Dallelaste , Puhl Eduardo
Published: May 2022

Considerando que a Lei n. 13.964 inseriu o acordo de não persecução penal (ANPP) no artigo 28-A do Código de Processo Penal, o qual prevê, que preenchidos os requisitos legais, o Ministério Público deve oferecer um acordo ao acusado para evitar uma persecução penal, objetiva-se analisar sua compatibilidade com o princípio constitucional da presunção de inocência. Para tanto, analisa-se o conceito, evolução histórica e natureza jurídica do ANPP, além de identificar a importância do princípio da presunção de inocência, no intuito de identificar eventuais conflitos e tensões, a partir de um método dedutivo, utilizando técnica de revisão bibliográfica e análise jurisprudencial. Observou-se que o acordo de não persecução penal por si só pode ser benéfico, mas também poderia trazer prejuízos ao acusado, especialmente quando estabelece a confissão da prática do delito como requisito formal. Por fim, verificou-se que uma possível solução para o conflito seria a desnecessidade de confissão do crime, preservando o direito constitucional do acusado de que não ser considerado culpado antes o trânsito em julgado da sentença penal condenatória.
afetividade como parâmetro para o reconhecimento jurídico da multiparentalidade
Authors: Loth Vilmar dos Santos , Toporoski Elizeu
Published: May 2022

A presente pesquisa tem como objetivo analisar a corrente divergente que surgiu com base na decisão do Supremo Tribunal Federal no Recurso Extraordinário n. 898.060/SC a fim de responder o seguinte questionamento: é possível o reconhecimento da multiparentalidade sem estar presente a afetividade e a convivência de filiação entre os envolvidos nessa relação? Embora a decisão seja uma importante conquista para o Direito de Família em diversos aspectos, uma discussão se instaurou com relação ao ponto em que reconheceu a multiparentalidade. Como será exposto, a corrente divergente considera que a multiparentalidade não estava configurada no leading case posto que a autora da ação já possuía um pai socioafetivo e não possuía convivência de filiação com o ascendente genético. Assim, para responder o questionamento, a pesquisa demonstrará que a parentalidade configura-se através da afetividade que se sobrepõe aos liames biológicos. Ademais, a mera comprovação do vínculo genético não é suficiente para constituir a multiparentalidade. Portanto, concluirá que o reconhecimento da multiparentalidade determina-se, justamente, pela existência ou não da afetividade e vínculo de filiação entre os envolvidos. Para o desenvolvimento da presente pesquisa foi utilizado o método dedutivo de abordagem, aplicando-se como técnica de pesquisa a revisão bibliográfica e documental. Primeiramente, será exposto o histórico da família. Após, abordará a afetividade como princípio basilar no Direito de Família. Por fim, a pesquisa fará considerações a partir do caso paradigmático do recurso extraordinário.
proposta terapêutica como alternativa ao enfoque repressivo das medidas protetivas de urgência
Authors: Artner Monique Thuany , Taporosky Filho Paulo Silas
Published: May 2022

O presente escrito tem como objetivo apresentar as inovadoras medidas terapêuticas utilizadas como tratamento para o agressor de violência contra a mulher. Por conseguinte, diferentemente do que nos é apresentado como medida de solução no processo penal, os autores da agressão podem rever seus comportamentos e adotar novas condutas perante a sociedade, analisando as medidas punitivas e seu êxito em relação a reincidência da violência e na mudança do comportamento do agressor, conforme alteração na Lei Maria da Penha, dada pela Lei 13.984/20. Destarte, expõe-se o contexto histórico da violência doméstica e os motivos para sua delongada normatização, assim como a construção social de gênero que possui notável influência no que concerne ao problema da violência no âmbito doméstico e familiar. Posto isto, deve-se analisar a inserção da criminologia feminista como nova forma de criminologia, trazendo a possibilidade de expurgar a invisibilidade dada a mulher como atuante no processo penal. A elaboração do presente artigo se pautou em revisão bibliográfica com abordagem da inovação legislativa pelo método hipotético-dedutivo.
eficácia do Estatuto do Desarmamento na redução dos homicídios por arma de fogo no Brasil
Authors: Luz Gabriel Lucas da , Boldori Marcelo José
Published: May 2022

O trabalho proposto visa compreender qual é a eficácia da Lei 10.826/2003, mais conhecida como Estatuto do Desarmamento, em relação aos índices de homicídios por arma de fogo desde a sua implantação no Brasil. Posterior ao seu sancionamento, houve pelo Senado Federal a promulgação de um referendo que consultou os cidadãos brasileiros no dia 23 de outubro de 2005 se a comercialização de armas de fogo devia ser proibida no Brasil. Após dezoito anos da vigência da Lei das Armas, o questionamento advindo da sociedade sobre a legitimidade do Estatuto diante da vontade soberana popular, bem como sua proficuidade em conter à criminalidade, vem crescendo devido às estatísticas de violência cometidas no país.
“Pai, eu quero pão!”
Authors: Prust Matheus Theodorovitz
Published: May 2022

Com os avanços das estruturas de entretenimento do Planalto Norte catarinense no início do século XX, muitos músicos foram atraídos para as cidades do interior do estado, colaborando para o desenvolvimento do cenário artístico local. Na ocasião dos 100 anos da chegada de Jack Dinkhuysen (1902-1975) no Brasil, neste texto busco lançar luz sobre a vida e atuação do maestro, que viveu em Santa Catarina entre os anos 1931 e 1935. Vindo da Holanda em 1922, o maestro se estabeleceu na cidade de Canoinhas, onde formou uma sociedade musical, duas jazz bands, produziu um festival de arte e lecionou piano e outros instrumentos. Apesar de sua importante contribuição, Jack Dinkhuysen ainda não havia sido mencionado nas diversas publicações da musicologia catarinense, fato que se passa, igualmente, com muitos músicos que tiveram importante participação no estado mas que, por motivos diversos, não entraram para os anais da história. A investigação se deu através da pesquisa em periódicos, com destaque para o jornal “Avante!” (1930-1935), além de periódicos do Rio Grande do Sul, documentos cartoriais e entrevistas. Este ensaio sobre Jack Dinkhuysen, por seu ineditismo, deve ser entendido como um ponto de partida que pode levar a discussões mais aprofundadas.
Palavras-chave: Jack Dinkhuysen. Jazz bands. Músicos em trânsito. Musicologia Catarinense. História da Música em Santa Catarina.
Protective role of autophagy in triptolide-induced apoptosis of TM3 Leydig cells
Authors: Ye Xiaoyun , Chen Liang
Published: May 2022

Background and Objectives

Triptolide (TP) is known to impair testicular development and spermatogenesis in mammals, but the mechanism of the side effects still needs to be investigated. The aim of the research is to confirm whether TP can cause autophagy in TM3 Leydig cells and the potential molecular pathway in vitro.

Methods

TM3 Leydig cells are used to investigate the molecular pathway through Western blot, detection of apoptosis, transmission electron microscopy for autophagosomes and so on.

Results

The data show that TP treatment resulted in the decreasing of the viability of TM3 cells due to the increased apoptosis. Treated with TP, the formation of autophagosomes, the decrease in P62, and the increase in the conversion of LC3-I to LC3-II suggested the induction of autophagy. The induction of autophagy has accompanied the activation of the mTOR/P70S6K signal pathway. The viability of the TM3 cells was further inhibited when they were co-treated with autophagy inhibitor, chloroquine (CQ).

Conclusion

All these data suggest that autophagy plays a very important role in antagonizing TM3 cell apoptosis during the TP exposure.