bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS PERFORMA FLASH TANK BRINE GEOTHERMAL MENGGUNAKAN SIMULASI CFD
Authors: Muzakki Syafiq Akmal , Khasani Khasani , Fauzun Fauzun
Published: January 2024

Sampah merupakan salah satu masalah utama dimasa ini. Seiring dengan meningkatnya penduduk, akan meningkat juga kebutuhan konsumsi masyarakat serta limbah yang dihasilkan. Menurut data dari Kementrian Lingkungan Hidup dan Kehutanan, sampah yang dihasilkan di Indonesia pada tahun 2021 sebanyak 28,58 juta ton/tahun, sedangkan sampah plastik menyumbang 17,77% dari total sampah, dan hanya 8,5% dari total sampah plastik yang berhasil diolah. Metode pengolahan sampah menggunakan metode pirolisis dapat mengubah limbah plastik menjadi polimer yang dapat dimanfaatkan menjadi bahan bakar. Untuk meningkatkan penggunaan metode pirolisis, limbah kalor brine hasil buangan pembangkit PLTP dapat dimanfaatkan sebagai sumber kalor dalam alat pirolisis. Brine buangan akan diinjeksikan kedalam sumur setelah melalui sistem flashing yang akan mengubah brine menjadi uap sebagai sumber energi reaktor pirolisis. Dalam penelitian, dilakukan perhitungan desain flash tank untuk menghasilkan uap panas untuk proses pirolisis, kemudian dilakukan simulasi CFD serta memvariasikan kondisi operasi sistem untuk menganalisis performa sistem. Adapun variasi berupa laju aliran massa serta kondisi tekanan operasi. Dari hasil analisis didapatkan peta performa separator yang dapat menghasilkan rentang operasi yang beragam dan dapat memaksimalkan kebutuhan sistem alat pirolisis. Flash tank diharapkan dapat digunakan untuk memanfaatkan brine panas dalam sistem pirolisis untuk mengurangi jumlah limbah plastik dengan mengubahnya menjadi bahan bakar alternatif
Subsurface delineation of Sukadana Basalt Province based on gravity method, Lampung, Indonesia
Authors: Siringoringo L. P. , Sapiie B. , Rudyawan A. , Sucipta I.G.B.E.
Published: January 2024

Research subject. The geological profile of Sukadana Basalt Province as a large basalt outcrop in the back arc of Sumatra remains to be unclear. This also concerns the geological structures and their relationship with the Sundaland regional geology. Aim. To reveal the type and pattern of geological structures that controlled the Sukadana Basalt Province (SBP) to the surface, the distribution of Sukadana Basalt on subsurface and its relationship with Sundaland regional tectonics. Materials and Methods. A reprocessed bouguer anomaly map of Tanjungkarang quadrangle 1991 was used. Results. We found that the main eruption was located in the center of SBP. The forward modeling data show the thickness of SBP to reach 3,200 m. There are two Northwest-Southeast striking normal faults and one fissure controlling the development of SBP. These fractures served as the primary conduit for magma to ascend from the mantle to the Earth’s surface. We also found North-South striking normal faults and West-East dextral strike-slip fault that formed at Early Oligocene and indirectly supported the magma ascend to the surface. Conclusions. The North-South striking normal faults were correlated with the Sundaland oroclinal bending. These faults developed through the extrados zone, a large pull-apart area that caused the continental lithosphere to become thinner. Meanwhile, Quaternary-Northwest-Southeast striking fractures are correlated with the development of the Great Sumatra Fault. The formation of Northwest-Southeast striking fractures was affected by the Great Sumatra Fault movement, and the thinning of the back-arc crust affected by multi-extensional structures was implicated in the ascend of SBP’s magma to the surface.
Study on the Emotional Adaptation of Multicultural Adolescents: Focusing On A Hermeneutic Application of Multicultural Settlement Narrative of the Characters of the Book of Daniel
Authors:   The Research Society for the Korean Language Education, Kim Young Joo , Kim Hyun Jin
Published: January 2024

This study aims to examine the difficulties of emotional adaptation experienced by multicultural youth that are rapidly increasing in Korean society and to help solve them.
Methods: This study will examine the various emotional difficulties they face through the three narratives of the characters in Daniel's book. We will also seek solutions to the emotional difficulties of multicultural youth through the convergent application of literary therapy (narrative therapy) methods, Gadamer's hermeneutic methods, and hermeneutic phenomenology with psychological emotions.
Results: The food rejection and the king's test narrative in Danielle 1 was related to self-positivity and optimism emotions also related to stress and health. Azariah's prayer narrative overcame the fear of death by healthy emotional resources such as 'high spirituality and resilience, self-regulation and persistence'. Susana's narrative showed that even in high-stress or hopeless trauma situations, people with healthy emotions bring post-traumatic growth, and post-traumatic growth is a virtuous cycle of more desirable emotional adaptation.
Conclusions: The various techniques of hermeneutic application of Daniel's narrative will help multicultural youth find their own solutions and self-understanding of the emotional difficulties they face entering Korean society today.
Conselho de classe: espaço-tempo de formação docente em escola militarizada
Authors: Rocha Rhaíssa Sheri Freire de Souza , Fernandes Silva Edileuza
Published: January 2024

No bojo da expansão da militarização de escolas públicas, o governo do Distrito Federal aderiu ao projeto em 2019, compartilhando a gestão de escolas com forças militares. Essa proposta tem gerado debates efervescentes, especialmente no que concerne à atividade docente e à organização do trabalho pedagógico. Este artigo, objetivou discutir o conselho de classe como espaço-tempo de organização o trabalho pedagógico e de formação docente em uma escola pública militarizada do Distrito Federal. O estudo se fundamenta em uma perspectiva crítico-dialética e os dados foram produzidos por meio de: análise documental; observação de reuniões de conselho de classe; entrevista semiestruturada com professores, coordenadora pedagógica e gestor disciplinar; e grupo de discussão com estudantes. Verificou-se que o conselho de classe se constitui colegiado integrante da gestão democrática; e tem relevante papel na formação docente, podendo fomentar reflexões acerda de questões relacionadas aos princípios e práticas de uma escola militarizada.
Lacuna de tecnologia na Formação Docente: uma análise na perspectiva do pensamento reflexivo
Authors: Kuhl Marcelo Guilherme , Pontarolo Edilson
Published: January 2024

Este artigo apresenta resultados parciais de pesquisa de mestrado que, à luz do conceito de educação reflexiva, investigou processos formativos relativos à apropriação e uso de novas tecnologias de informação e comunicação pelos estudantes de um Curso de Formação de Docentes da educação infantil e anos iniciais do ensino fundamental, em nível médio, na modalidade normal, de um colégio estadual do Paraná. Empregamos aporte teórico da epistemologia do pensamento reflexivo e de autores que problematizam relações entre tecnologia e educação. Esta pesquisa qualitativa empregou amostragem intencional. Os dados analisados especificamente neste artigo foram obtidos por meio de entrevista de grupo focal realizado com estudantes do quarto ano do referido curso. Os dados foram submetidos à Análise de Conteúdo para formação de categorias. Os resultados indicam que é necessário intensificar a formação inicial e continuada na educação em termos de Novas Tecnologias de Informação e Comunicação.
Estabilidad oxidativa de aceite de sacha inchi (Plukenetia volubilis Linneo) microencapsulado enriquecido con compuestos fenólicos extraídos de su cascarilla
Authors: Betancourt López Cristhian Fernando , Rodríguez-Stouvenel Aida , Millán-Cruz Patricia
Published: January 2024

El sacha inchi (SI) es una planta autóctona de la Amazonía, cuyas semillas se destacan por su alto contenido de ácidos grasos poliinsaturados, en particular el omega 3 (18:3n-3, ácido linolénico). Las semillas de SI empleadas en este trabajo contienen 37.9 ± 1.2% de aceite, en el cual 45.90 ± 0.26% es ácido linolénico. En el proceso de extracción del aceite de sacha inchi se retira la cascarilla (CSI), que representa el 31.30 ± 0.50% del total de la semilla. Este subproducto contiene concentraciones significativas de polifenoles (3372 + 23 mg AGE/100 g FW). El aceite de sacha inchi (ASI), junto con el extracto vegetal de polifenoles de la cascarilla, se micro encapsuló mediante secado por aspersión, utilizando maltodextrina y goma arábiga como materiales de recubrimiento. La efectividad de la microencapsulación se evaluó mediante pruebas fisicoquímicas, como contenido de humedad (3.27%), actividad de agua (0.256 ± 0.015), tamaño de las microcápsulas (9.15 y 15.13 μm), solubilidad (88.40 ± 0.10%), humectabilidad (6.5 minutos) y digestión in vitro (50.38 ± 1.19% de aceite liberado). La estabilidad oxidativa de las microcápsulas de ASI enriquecido se evaluó mediante el método Rancimat, revelando el efecto significativo de la microencapsulación al aumentar la vida útil del aceite microencapsulado en un 64% en comparación con el aceite líquido. La oxidación del producto final se evaluó en una cámara de almacenamiento con temperatura (35°C) y humedad (80%) controladas durante 60 días, donde el índice de peróxidos al final del período de seguimiento no superó los 4.22 ± 0.20 meq O2/kg de aceite. Este estudio demuestra la viabilidad tecnológica del proceso de microencapsulación del ASI enriquecido con compuestos fenólicos para prolongar su vida útil.
Sistema de interacción humano-robot para la enseñanza-aprendizaje de una tarea de ordenamiento de objetos mediante comunicación verbal y gestual
Authors: Nope Rodríguez Sandra Esperanza , Mosquera-DeLaCruz Jose Hernando , Martínez-Álvarez Alexander , Loaiza-Correa Humberto , Rodríguez-Téllez Gabriel Alejandro , Jamioy-Cabrera Juan David , Delgado-Giraldo María De Los Ángeles , Penagos-Angrino Juan Felipe
Published: January 2024

Se desarrolló un sistema interacción humano-robot multimodal (gestos y voz) que permite a usuarios enseñarle tareas de clasificación de cubos por color a un robot. La evaluación del sistema fue realizada por siete usuarios de forma cuantitativa y cualitativa. En las pruebas cuantitativas se evaluó un total de 63 interacciones verbales, 252 interacciones gestuales, y 63 multimodales. El porcentaje de reconocimiento de las interacciones fue del 98.41% para los comandos de voz, 81.35 % para los gestuales, y 80.95% para las multimodales. Luego del aprendizaje, el robot fue capaz de realizar correctamente la tarea de clasificación de cubos por color en un 100%; siendo capaz de responder exitosamente ante condiciones iniciales (ubicaciones y cantidad de cubos) no enseñadas previamente. La evaluación cualitativa del sistema se realizó para conocer la percepción de los usuarios, arrojando resultados consistentes con los porcentajes de reconocimiento, favoreciendo la interacción verbal sobre la multimodal.
SOBRE QUE MILITANTES E ENGAJADOS ESTAMOS FALANDO?
Authors: Moraes Fabiana
Published: January 2024

RESUMO – Este artigo problematiza, inicialmente, como os termos ativista/militante/engajado também devem qualificar a imprensa comercial brasileira. Depois, realiza uma distinção teórica dos termos citados e busca avançar na ideia de posicionamento como uma prática política possível em redações variadas, podendo também não ser declarada. A pesquisa se baseia em revisão bibliográfica e análise crítica que tensiona elementos da objetividade jornalística. Apontamos, no final, para uma prática reflexiva (anunciada ou não) que colabore para uma necessária maior densidade democrática na imprensa brasileira.
ABSTRACT – In this article we initially problematize the terms activist/militant/engaged and how they should also be included to qualify the Brazilian commercial press. We then perform a theoretical contrast of these terms and propose the idea that political positioning is being practiced in newsrooms, which they may also not announce. The research is based on a bibliographic review and critical analysis of elements of journalistic objectivity. We point, in the end, to a reflective practice (announced or not) that collaborates for a necessary greater democratic density in the Brazilian press.
RESUMEN – Este artículo inicialmente problematiza cómo los términos activista/militante/comprometido también deberían calificar la prensa comercial brasileña. Posteriormente, realiza una distinción teórica de los términos citados y busca avanzar la idea del posicionamiento como posible práctica política en diversas redacciones, que también puede no ser declarada. La investigación parte de una revisión bibliográfica y un análisis crítico que destaca elementos de objetividad periodística. Apuntamos, al final, a una práctica reflexiva (anunciada o no) que colabora para una necesaria mayor densidad democrática en la prensa brasileña.
Two new species of the ant genus Plagiolepis Mayr, 1861 (Hymenoptera: Formicidae: Fomicinae) from Indochina
Authors:   Forest Entomology and Microbiology Research Group, Forest and Plant Conservation Research Office, Department of National Parks, Wildlife and Plant Conservation, 61 Phahonyothin Road, Chatuchak, Bangkok 10900, Thailand, Phosrithong N. , Rattanachan K. ,   Forest Entomology and Microbiology Research Group, Forest and Plant Conservation Research Office, Department of National Parks, Wildlife and Plant Conservation, 61 Phahonyothin Road, Chatuchak, Bangkok 10900, Thailand, Satakoune L. ,   ) Faculty of Natural Science, Champasak University, 13th Road, Champasak Province 16000 Laos, Jaitrong W. ,   Office of Natural Science Research, National Science Museum, 39 Moo 3, Khlong5, Khlong Luang, Pathum Thani, 12120 Thailand
Published: January 2024

Two new species, Plagiolepis chomphuphuangi sp. n. and Plagiolepis chomphuphuangi sp. n., are described based on the worker caste from Laos and Thailand, respectively. The type series of former species was collected on the ground in a coffee plantation at highland (ca. 1000 m). Plagiolepis silpaarchai sp. n. inhabits lowland (ca. 250 m), and the type series was collected with a pitfall trap in a disturbed area near a mixed deciduous forest during the dry season. A key to the Southeast Asian species of the genus Plagiolepis Mayr, 1861 is provided.
New Validated LC-MS Method Development and Estimation of Nitrosamine impurities in Canaglifozin
Authors: Mohammed Mubarakunnisa , R Gandhimathi
Published: January 2024

Background: Canagliflozin is most prescribed anti-diabetic drug, as diabetic drugs are consumed daily there may be a chance of consuming nitrosamine impurities beyond their limits hence, the Food and Drug Association (FDA) recommends checking for carcinogenic impurities in routine use drugs. Aims and Objectives: The study aims to simultaneous estimation of 4 nitrosamines (NMDA, NEIA, NIEA, and NDIPA) by liquid chromatography-mass spectrometry (LCMS) to detect the limit of detection (LoD) and limit of quantitation (LoQ). estimation of these impurities (NMDA, NEIA) in canagliflozin tablet dosage form with specificity parameters. Methods: Drug canagliflozin was collected from hetero labs, methanol, LC-MS grade acetonitrile, formic acid four impurities (NMDA, NEIA, NDIPA, NIEA) purchased from Merck Pharmaceuticals Mumbai. The Zorbax SB C18 column (250 x 4.6 mm, 3 mcm) is used as the stationary phase, 0.1% formic acid and acetonitrile in the ratio of 70:30 is used as the mobile phase, methanol is used as diluent flow rate was maintained at 1-mL/min, the injection volume was fixed to 10 mcl, which is run at 10 minutes. The electron ionization ion source, multiple reaction monitoring, and acquisition mode is used for the study. The time required for the solvent delay and detector off is 4 and 9.5 minutes, respectively. The product ions peaks of impurities were observed at 44 for NDMA, 99 for NEIA. Results: The %RSD for the peak areas of NDMA, NEIA obtained from six replicate injections of standard solutions were 2.5, 9.8, 1.4 and 7.7, respectively. The %recovery of NDMA and NEIA were within the limit. The %RSD for the results obtained from the method precision study was within the limit. Conclusion: The above observations indicate that the LC-MS method meets the acceptance criteria for the parameters selected for the validation study. Hence, the method is suitable for the determination of NDMA, NEIA in a Drug Substance by LC-MS.
ELECTRICAL, OPTICAL, AND CHEMICAL PROPERTIES OF GRAPHENE THIN FILMS FABRICATED BY VACUUM FILTRATION TECHNIQUE
Authors: Haji Shivan H. , Kochary Faris A. , Ahmed Sabah M.
Published: January 2024

There has been considerable interest in graphene as a transparent electrode material because of its extraordinary features, such as high optical transmittance, high electrical conductivity, excellent thermal conductivity, exceptional mechanical strength, and remarkable electrochemical capacity. In addition, transparent conductors’ graphene thin films have been considered a promising candidate to replace currently utilized indium tin oxide films, which are unlikely to meet future demands because of their rising cost. In this study, a vacuum filtration process along with isopropyl alcohol (IPA)-assisted with direct transfer (IDT) technique is used to prepare wide-area highly conductive graphene thin films on different substrates including (glass, and PET). The graphene thin films' optical, structural, and electrical properties are studied. The graphene sheets are deposited homogeneously on the substrate, and the distribution of small graphene sheets is observed in SEM images. XPS analysis revealed that the amount of oxygen in graphene decreases significantly with annealing at 500°C and treated with HNO3. Furthermore, the graphene transparent conductive films prepared by the adjusted vacuum filtration method show low sheet resistances of 12.2, 1.41, 1.18, and 0.8 kΩ/sq with transmittances of 81%, 70%, 64.3%, and 46.4% respectively after being annealing at 500°C and treated with HNO3.
New domestic intraocular lenses. Resistance to biodegradation processes in comparison with foreign analogues
Authors:   S. Fyodorov Eye Microsurgery Federal State Institution, Moscow, Russian Federation, Khliyan K.G. , Omarieva I.R. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Moscow, Russian Federation, Kopaev S.Y. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Moscow, Russian Federation
Published: January 2024

Relevance. Due to the high demand for import substitution, the prospect of assessing the long-term results of implantation of domestic models of intraocular lenses (IOL) will determine their place among a wide range of models offered by modern manufacturers in our country and abroad. Purpose. To evaluate, in an in-vitro experiment on aging modeling, the resistance of new domestic IOLs to biodegradation processes in comparison with foreign analogues. Material and methods. 3 IOLs of the following models were taken: domestic IOLs made of hydrophobic acrylic: Citrine, Citrine TT, Citrine Action; domestic hydrophilic acrylic Aquamarine IOLs. Foreign hydrophobic acrylic IOLs of the AcrySof SN60AT model and hydrophilic IOLs of Rumex rAqua-4 were taken as reference. Before the experiment, the optical parameters of the studied IOLs were measured: optical power, modulation transmission function (MTF), Strel number. The induction of glistening was carried out as follows: IOLs immersed in a BSS solution were placed in an oven foR²4 hours with a temperature of 45 °С. Further, cooling was carried out to 37 °С foR².5 hours. IOL photofixation was performed at 80-fold magnification with an assessment of the degree of glistening. Optical parameters were repeatedly measured. Results. Glistening was not detected in Aquamarine IOL and Rumex rAqua-4. The 2nd and higher degree of glistening was not detected in any model of hydrophobic IOLs. The optical strength of all the studied IOLs changed in the range from 0.23 to 1.6%. MTF changes ranged from 0 to 3.7%. The number of Strel has changed in the range from 0 to 8.5%. The absence of glistening in hydrophilic IOLs can be explained by a more uniform distribution of water in the material. Differences in the degree of glistening in hydrophobic IOL models may be due to differences in production methods. The revealed changes in optical parameters are insignificant and do not exceed the limits of state standards. Conclusion. Domestic IOLs represent a worthy competition to foreign models, as they have advantages in terms of the availability of high-quality IOLs of aspherical design and a reduced degree of susceptibility to glistening. Key words: domestic intraocular lenses, hydrophobic acrylic, hydrophilic acrylic, glistening, inducing glistening, modeling of IOL aging
Physico-chemical analysis of hydrophilic intraocular lenses explanted due to material clouding
Authors:   S. Fyodorov Eye Microsurgery Federal State Institution, Orenburg branch, Orenburg, Russian Federation, Chuprov A.D. , Kim V.L. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Orenburg branch, Orenburg, Russian Federation, Letuta S.N. ,   Orenburg State University, Orenburg, Russian Federation, Razdobreev D.A. ,   Orenburg State University, Orenburg, Russian Federation
Published: January 2024

Relevance. Clouding and discoloration of intraocular lens (IOL) seems to be a multifactorial problem, directly related to the properties of each group of materials from which they are made. Since the exact combination of factors and the sequence of events are not yet fully known, there is reason to continue research in this direction, even though, unfortunately, such important points as the specifics of IOL production are information closed to the general public. It is also obvious that this problem is urgent and requires an integrated approach. Purpose. To determine the type of deposits on the surface of hydrophilic IOLs explanted due to a decrease in the transparency of the material. Material and methods. Visualization of the surface of 8 explanted hydrophilic IOLs was carried out in a digital inverted microscope Altami INVERT 3 (LLC Altami, Russia). Elemental analysis of surface deposits was carried out on a JCM-6000 electron microscope (Jeol, Japan) with a JED-2300 energy dispersive analysis attachment. The Raman spectra were measured using M532 Raman microscope (Enspectr, USA). Infrared absorption spectra (IR spectra) were recorded using equipment: Fourier spectrometer InfraLum FT-02 (Lumex, Russia) and an IR spectrometer with an attachment of frustrated total internal reflection IRTracer-100 (Shimadzu, Japan). The processing and interpretation of the obtained spectra was carried out using databases and software from the equipment. Results. The nature of the deposits is represented by various crystallites, in some places forming a completely continuous film. The main elements of deposits are carbon, nitrogen, and oxygen. The IR spectrum contains functional groups characteristic of proteins. Conclusion. Deposits on the surface of a cloudy IOL of a hydrophilic type are of protein nature. The fact that the deposits have a crystalline structure makes it possible to significantly narrow the scope of the search for those compounds that are capable of crystallizing at temperatures close to the normal temperature of the human body. Key words: IOL clouding, hydrophilic IOL, IOL explantation
The Effect Word of Mouth on Saving Intention Through Brand Image as an Intervening Variable
Authors: Kharisma Yussitha  , Irmayanti Hasan  , Yayuk Sri Rahayu
Published: January 2024

Word of mouth and brand image are factors in forming someone's intention to use a product. This condition requires the company to continue to provide comfort for every use of its products. The purpose of this study was to examine the direct effect of word of mouth on the intention to save through the BMT Alhikmah brand image. This study uses a quantitative method with the help of SmartPLS software to assist data analysis. The sample approach used was simple random side by way of distributing questionnaires and collecting 95 respondents. The results of this study indicate that word of mouth has a direct effect on saving intention. The involvement of word of mouth also has a direct effect on brand image, whereas brand image has no direct influence on the intention to save at BMT Alhikmah. In addition, the results of this study indicate that word of mouth does not have a direct effect on saving intention through brand image as an intervening variable. The research weakness lies in the brand image variable which does not have a direct effect on the intention to save BMT Alhikmah.
Peran Profitabilitas dalam Memoderasi Kinerja Lingkungan, Islamic Social Reporting dan Ukuran Dewan Komisaris Terhadap Nilai Perusahaan
Authors: Mia Fitriani  , Puji Endah Purnamasari
Published: January 2024

Tujuan dari dilakukan penelitian ini adalah untuk mengetahui faktor-faktor yang dapat memengaruhi nilai perusahaan dengan dilakukan pengujian interaksi menggunakan profitabilitas. Populasi dalam penelitian ini yaitu seluruh perusahaan yang masuk daftar Jakarta Islamic Indeks selama kurun waktu 2017-2021 yang berjumlah 53 perusahaan. Perolehan sampel dilakukan dengan teknik purposive sampling dan diperoleh 8 perusahaan. Penelitian ini menggunakan pendekatan kuantitatif dengan data sekunder dan analisis data dibantu dengan sofware eviews-12. Hasil yang diperoleh dari penelitian ini yaitu kinerja lingkungan dan Islamic Social Reporting (ISR) tidak berdampak pada nilai perusahaan, sedangkan ukuran dewan komisaris berdampak negatif signifikan pada nilai perusahaan. Profitabilitas tidak mampu memoderasi kinerja lingkungan terhadap nilai perusahaan, namun memperlemah pengaruh dari  Islamic Social Reporting (ISR) dan ukuran dewan komisaris terhadap nilai perusahaan. Penelitian ini memiliki keterbatasan pada rasio profitabilitas yang hanya diukur dengan Return On Equity (ROE) serta hanya menggunakan 8 perusahaan sebagai sampel penelitian yang sesuai dengan kriteria penelitian.
Pengaruh Kualitas Produk Dan Harga Terhadap Keputusan Pembelian Produk Halal Di 212 Mart Medan Baru
Authors: Nabillah Syahwina Batubara  , Ahmad Afandi
Published: January 2024

Karena hadir untuk melindungi umat Islam dari fitnah agama, Minimarket 212 Mart Medan Baru menjadi fenomena yang menarik bagi para peneliti. Penelitian ini mencoba mengidentifikasi elemen-elemen yang mempengaruhi pilihan pembelian pelanggan dan harga barang halal di minimarket 212 Medan Baru. Informasi yang digunakan dalam penelitian ini berasal dari survei dengan kuesioner yang dilakukan dengan cara memberi seperangkat pertanyaan yang tertulis kepada responden yang berjumlah 101 responden dan kemudian untuk dijawab, yakni kuesioner yang sudah disediakan jawabannya, sehingga responden tinggal memilih dan menjawab secara langsung. Metodologi penelitian ini adalah kuantitatif. Analisis regresi linier berganda, uji statistik nonparametrik Kolmogorov-Smirnov (K-S), dan uji multikolinieritas jika VIF (faktor inflasi varian) adalah metode analisis data yang digunakan. Teknik analisis data menggunakan SPSS versi 26.0. Hasil pengujian hipotesis menunjukkan terdapat pengaruh kualitas produk terhadap produk halal (0,006 < 0,05), Hasil pengujian hipotesis menunjukkan terdapat pengaruh harga terhadap produk halal (0,001 < 0,05). Hasil pengujian hipotesis menunjukkan terdapat pengaruh keputusan pembelian terhadap produk halal (0,012 < 0,05). Dari hasil koefisien determinasi diperoleh 0,509 atau 50,9% menunjukkan bahwa variasi nilai kualitas produk, harga produk dan keputusan pembelian mencerminkan nilai kehalalan produk. Sisanya sebesar 49,1% dipengaruhi oleh faktor-faktor lainnya.
Association Between Palatally Impacted Maxillary Canine and Anomalous Maxillary Lateral Incisor - A Case Control Study
Authors:   Saidu College of Dentistry, Swat, Afsar Rozi , Nasir Umar , Maryam Bibi , Elahi Atta , Saboor Abdus , Afsar Badshah
Published: January 2024

OBJECTIVE: To determine the association between palatally impacted maxillary canine (PIC) and anomalous upper lateral incisor. METHODOLOGY: This case control study was conducted on records of 60 participants (30 with PIC and 30 without). The inclusion criteria were participants without syndromes, palatal canine impaction (cases only), and age range from 12 to 30 year. Subjects with buccally impacted canine, history of previous orthodontic treatment and non-Pakistani nationals were excluded. Cases were those having PIC and controls were without PIC. Participant's OPG and periapical X-rays were used to diagnose PIC by horizontal parallax technique. Dental anomalies in upper lateral incisor were diagnosed by using casts and OPGs. Logistic regression and chi-square test was applied to determine association between PIC and anomalous upper lateral incisor. RESULTS: The mean age of the participants was 18.916±4.3 years. The frequency of missing lateral incisor was higher in cases (n=3, 10%) than control (n=1, 3.3%). Similarly peg shape laterals was more in cases (n=4, 13.3%) than controls (n=2, 6.7%). However this association was not statistically significant (P=0.37). The odd of having anomalies in lateral incisor was 2.73 times higher in cases than controls but the results were not statistically significant (P=0.177). CONCLUSION: Though the frequency of anomalous maxillary lateral incisors is higher in participants with PIC than controls but this association was not statistically significant. KEYWORDS: Palatal canine impaction, missing upper lateral incisors, peg shape upper lateral incisors, dental anomalies
Design, synthesis, and biological characterization of proteolysis targeting chimera (PROTACs) for the Ataxia telangiectasia and RAD3-related (ATR) kinase
Authors: Alfayomy Abdallah M. , Ashry Ramy , Kansy Anita , Sarnow Anne-Christin , Erdmann Frank , Schmidt Matthias , Krämer Oliver H. , Sippl Wolfgang
Published: January 2024

The Ataxia telangiectasia and RAD3-related (ATR) kinase is a key regulator of DNA replication stress responses and DNA-damage checkpoints. Several potent and selective ATR inhibitors are reported and four of them are currently in clinical trials in combination with radio- or chemotherapy. Based on the idea of degrading target proteins rather than inhibiting them, we designed, synthesized and biologically characterized a library of ATR-targeted proteolysis targeting chimera (PROTACs). Among the synthesized compounds, the lenalidomide-based PROTAC 42i was the most promising. In pancreatic and cervix cancer cells cancer cells (MIA PaCa-2), it reduced ATR to 40% of the levels in untreated cells. 42i selectively degraded ATR through the proteasome, dependent on the E3 ubiquitin ligase component cereblon, and without affecting the associated kinases ATM and DNA-PKcs. 42i may be a promising candidate for further optimization and biological characterization in various cancer cells.
A Spanish Chemoinformatics GitBook for Chemical Data retrieval and Analysis using Python Programming
Authors: Saldívar-González Fernanda I. , Prado-Romero Diana L. , Cedillo-González B. Raziel , Chávez-Hernández Ana L. , Avellaneda-Tamayo Juan F. , Gómez-García Alejandro , Juárez-Rivera Luis , Medina-Franco José L.
Published: January 2024

Searching, retrieving, and analyzing chemical information is one of the main tasks faced by students and professionals in chemistry-related scientific disciplines. Currently, freely available modules developed in programming languages, such as Python, allow efficient data management and facilitate obtaining information and knowledge from the data. This manuscript describes an electronic handbook generated on the GitBook platform to introduce the Python programming language and the Analysis, computational representation, and visualization of chemical data. This manual explores the most common molecular representations of low molecular weight organic compounds and their applications in various contexts. It also illustrates the acquisition of chemical information from large public molecular databases such as ChEMBL and PubChem and the Analysis and visualization of chemical information using concepts such as chemical space. The GitBook is freely available and is expected to foster open science and facilitate learning for chemistry students at the undergraduate and graduate levels and professionals interested in chemical data analysis and visualization.
Site-Specific β-C(sp3)–H Fluorination of N-Substituted Amines: A Late-Stage Functionalization Strategy Enabled by Electrochemistry
Authors: Novaes Luiz , Ho Justin , Mao Kaining , Villemure Elisia , Terrett Jack , Lin Song
Published: January 2024

Incorporation of C(sp3)–F bonds in biologically active compounds is a common strategy employed in medicinal and agricultural chemistry to tune pharmacokinetic and pharmacodynamic properties. Due to the limited number of robust strategies for C(sp3)–H fluorination of complex molecules, time-consuming de novo syntheses of such fluorinated analogs are typically required, representing a major bottleneck in the drug discovery process. In this work, we present a general and operationally simple strategy for site-specific β-C(sp3)–H-fluorination of amine derivatives including carbamates, amides, and sulfonamides, which is compatible with a wide range of functional groups including N-heteroarenes. In this approach, an improved electrochemical Shono oxidation is used to set the site of functionalization via net ⍺,β-desaturation to access enamine derivatives. We further developed a series of new transformations of these enamine intermediates to synthesize a variety of β-fluoro-⍺-functionalized structures, allowing efficient access to pertinent targets to accelerate drug discovery campaigns.
CONVERSION OF KITCHEN FOOD WASTE TO HALAL ORGANIC FERTILIZERS
Authors: Sulaiman Nor Surilawana , Rahim Siti Majidah , Jopry Nabilah Ulfah , Roslan Afifah , Mohamad Akil Syahid , Azri Irwandy Haziq Aiman , Hashim Norkhairiah
Published: January 2024

Food produced for human consumption can be wasted up to one-third of the time, causing economic, social, and environmental harm. The value of kitchen food waste is being increasingly recognised, and Brunei Darussalam ranks among the highest in the region, with a solid waste output of 1.4 kg per capita per day. However, just 11.3% of food waste is estimated to have been recycled, with the remainder ending up in landfills. In this context, the purpose of this paper is to provide recommendations for the most environmentally friendly means of disposing of kitchen food waste, with composting providing natural, halal, eco-friendly fertiliser. Thus, a two-month experiment was conducted to produce compost-based fertilizer from kitchen food waste. The nutritional value of the plant was then ascertained by fertilizing one plant of bird’s eye chillies (Capsicum frutescens L) with compost-based fertilizer (CBF) and another plant with clay-based soil (CBS). The results of this study showed that almost all the macronutrients in CBF plants are in the accepted range and show good compost fertilisation. Thus, it demonstrates how composting food waste from households can aid in the management of waste reduction for sustainable and a healthy environment, and nutrient recycling in agriculture.
EFFICACY OF DIFFERENT MULCHING MATERIALS ON PERFORMANCE AND YIELD OF OKRA IN MAHOTTARI, NEPAL
Authors: Chaudhary Bhagawan Lal , Dholi Pankaj Karki , Adhikari Safal , Khatiwada Pratibha
Published: January 2024

The efficacy of different organic and inorganic mulches in modulating the environment, growth, performance, and yield of okra [Abelmoschus esculentus (L.)] was compared in the field experiment in Matihani, Mahottari from 2078 Falgun to 2079 Ashad. Okra (variety SVOK 5151) was direct seeded in single rows. The experiment consisted of 5 treatments as follows: control, black plastic mulch, rice straw, wheat st, raw, and sawdust with four replications designed in RCBD. Seed germination significantly differed with the type of mulching material used. The highest seed germination percentage was recorded from the black plastic mulch plot and the lowest seed germination percentage was recorded from the control plot. The highest plant height was recorded from black plastic mulch at 20, 35, 50, and 65 DAS than that of other treatments. Black plastic mulch enhanced the number of leaves per plant than that of other treatments. Black plastic mulch enhanced the early flowering of okra leading to increased early and total yield of okra in comparison to bare soil. Vegetative attributes and yield-related attributes were found to be significantly better and higher in crops with plastic mulch rather than organic mulches. The highest productivity (30.93 Mg ha-1) was recorded from black plastic mulch followed by rice straw (24.71 Mg ha-1). Okra productivity with the highest net return and the highest benefit-cost ratio was obtained from black plastic mulching. The highest B: C ratio (3.23) and lowest B: C ratio (1.75) were calculated from the control plot. Because of these findings, it is believed that plastic culture has positive effects on the growth and yield of vegetables. The use of plastic mulch is an absolute tool for promoting vegetable production in Matihani. Further studies need to be performed to have a better understanding of the effects of vegetable crops grown with organic and plastic mulches.
EVALUATION OF DIFFERENT RATES OF COMPOST MINERAL FERTILIZER ON THE GROWTH AND YIELD OF TOMATO
Authors: Stephen O Dania, , Rita. I Eniola, , Felix. O Ogedegbe,
Published: January 2024

Compost – mineral fertilizer has dual effects; improving soil nutrient status and organic matter content which results to increase in yield of cultivated crops. A field experiment was carried out at the Ambrose Alli University Teaching and Research Farm, Ekpoma, Edo State, Nigeria to evaluate the effect of different rates of compost-mineral fertilizer and compost on the growth and yield of tomato. The experimental design was a Randomized Complete Block Design (RCBD) with seven treatments replicated thrice. The treatments were; control, recommended 10 tonnes of compost, 1, 2, 4, 6 and 8 tonnes/hectare (t/ha) of compost-mineral fertilizer. The initial soil analysis showed low nutrients status and the application of fertilizer was necessary to boost its fertility. Parameters taken were; plant height, stem girth, number of branches, number of flowers at 50% flowering, number of fruits and fresh weight of fruits. From the results, the application of 4, 6 and 8t/ha compost-mineral fertilizer significantly (p< 0.05) increased the growth and yield of tomato compared to other treatments. The yield of tomato obtained from the application of 4, 6 and 8 tonnes of compost- mineral fertilizer (252.50, 272.00 and 294.50 t / ha) were not significantly (p< 0.05) different from each other but significantly (p< 0.05) higher compared to other treatments. Therefore, the application of 6 t / ha of compost-mineral fertilizer can be adopted by farmers for tomato production in the study area.
Seroprevalence study of Parvovirus B19 among women with miscarriage in Mosul city
Authors:   Microbiology Department, College of Medicine, University of AL-Nahrain, Baghdad, Iraq, Nawfal Buraa Atheer , Baqer Al-Obaidi Asmaa , Ali Hussein Thekra
Published: January 2024

Background: Miscarriage and stillbirth are among the most common pregnancy complications, and could be caused by several factors, among these factors are viral infections some of them are obvious teratogenic and others are associated with fetal defects like severe anemia in the case of Parvovirus B19 which could be transmitted vertically causing fetal infection and miscarriage or stillbirth. Objective: To investigate the seroprevalence of Parvovirus B19 among women with miscarriage and stillbirth and compare them with normal pregnant women in the city of Mosul-Iraq. Patients and Methods: A case-control study conducted on pregnant aged 16-45 years with miscarriage and stillbirth admitted to Al-Khansa Teaching Hospital in Mousl city. The samples were collected during the period from November 2022 and January 2023 from 160 from pregnant women, 80 of them had miscarriage or stillbirth, and the other 80 had normal uneventfull pregnancy (control). Serum samples were subjected for ELISA Study of anti-B19V IgG and IgM antibodies. Results: This study showed that the seroprevalence rate of anti-B19V IgG among pregnant women was about 23% (37 out of 160), subdivided into (40%) 32 out of 80 patients, and (6.2%) 5 out of 80 controls had positive anti-B19V IgG antibody which is significantly different. And IgM seroprevalence was about 22% (35 out of 160), in which (38.8%) 31 out of 80 patients, and (5%) 4 out of 80 controls had positive anti-B19V IgM antibody. Both anti-B19V IgG and IgM were higher among patients who had stillbirth than those who had miscarriage both qualitatively and quantitatively. On the other hand, there is a highly significant association of anti-B19V IgM positivity with maternal anemia. Conclusion: The study found high association between B19V and miscarriage or stillbirth as compared to normal pregnancy, and this was more common among patients who had stillbirth than those who had miscarriage, with obvious association with maternal anemia, all of the above is among pregnant women from Mosul City in Iraq. Keywords: miscarriage , stilbirth
Congenital Heart Disease In Preterm Infants
Authors:   College of Medicine, University of Diyala , Diyala, Iraq, A Jassam Maymouna , S. Mahmood Najdat , Q. Mahmood Sura
Published: January 2024

Background: Congenital heart defects and preterm birth are two important causes of neonatal and infant mortality. However, the relationship between them has not yet been fully clarified. Objective: To find the association of congenital heart disease with premature delivery. Patients and Methods: The study is an observational cross sectional study, done in Al-Batool teaching hospital for maternity and children from July 2022 to January 2023. A self-prepared questionnaire was used to gather data. Gestational age was calculated mainly on postnatal gestational assessment by Dubowitz/Ballard method by a pediatrician. Echocardiography was done by Echocardiography specialist doctor to identify the presence and types of congenital heart defects. SPSS version 25 was used for statistical analysis. Results: Total number of births (term and preterm) was 1616, congenital heart diseases were detected in 60(3.71%) of them, most of them were isolated heart defect. In preterm babies, the congenital heart diseases were detected in 8% (p value was <0.001), they were of different types as followings: patent ductus arteriosus (n=10,26%), atrial septal defect (n=8,21%), ventricular septal defect (n=7,18%), transposition of the great arteries (n=4,10%), tetralogy of Fallot (n=2,5%), and complex of congenital heart disease (n=7,18%), while in full term babies, the rate of congenital heart diseases was only 1.9%. Conclusion: The incidence of congenital heart disease was higher in preterm than full term delivered babies, mostly in the group of transposition of the great arteries, ventricular septal defect, complex heart defects, followed by atrial septal defect. Keywords: Preterm, delivery, congenital heart disease.
The effects of the Federal Reserve Chair's testimony on Treasury interest rates
Authors: Gordon Matthew V. , Lunsford Kurt G.
Published: January 2024

Communication by the Federal Reserve is important for the conduct of monetary policy. We study how one form of Federal Reserve communication, the congressional testimony by the Chair of the Board of Governors (the Fed Chair), affects interest rates on 2-year and 10-year Treasury Notes. We study three types of Fed Chair testimony: the first day of Monetary Policy Report testimony, the second day of Monetary Policy Report testimony, and testimonies not associated with the Monetary Policy Report but that still relate to monetary policy. We find that the average size of interest rate changes is largest around first-day Monetary Policy Report testimonies and smallest around second-day Monetary Policy Report testimonies. We also document that the sizes of interest rate changes can vary over time and often correspond to the level of the federal funds rate.
Research on Renewal Design of Traditional Village Cultural Space Awakening Collective Memory
Authors: 杨 梦娇 , 高 博
Published: January 2024

历经城镇化的快速发展，乡村面貌非城非乡，暴露出文化空间缺失、集体记忆断层等问题。本文选取历史文化村落南焦村为更新试验点，直面为何与如何唤醒集体记忆两大核心，以“文化空间基因理论”为发力点，明晰特色资源要素的概念与分类；并在确定文化空间的典型样本后，结合融合共生的思想，遵循全链条的研究方法，实现理论与实践的有机结合，以期活化传统文化空间，唤醒村民的集体记忆，促进特色村镇的科学化保护与发展。
Tradition and Innovation: Tsinghua Urban Design Studio under the Circumstances of Urban Renewal
Authors: 钟 舸 , 边 兰春 , 黄 鹤
Published: January 2024

城市作为生命体的基本属性以及历时性特征,决定了城市总是在不断演变发展中,城市设计的本质就是展示这一演变过程,揭示这一演变规律,描绘这一演变路径和图景,因此,城市设计本身就具有与历史城市保护的“一体两面”属性,以及与城市更新的学理内核一致性。城市更新是城市的固有规律和必然过程,中国城市的更新本质是不断追求的现代化和城市现代性彰显,并在这一过程中留存历史记忆,实现历史文化的保护传承。正是基于对城市设计学科发展的长期深刻认识,以及从1999年开始的城市设计教学探索和积累,清华大学教学团队继承了清华大学城市设计与历史城市保护高度融合的学术思想和学术传统,依托北京城在名城保护和首都建设的国家战略性需求,从既有建成空间的形态秩序梳理和空间整合视角,运用城市形态学理论方法,系统培养学生对纷繁复杂的城市空间进行抽象、呈现、认识、建构能力,建立贯穿“建筑—建筑群—场地—城市”的跨尺度一体化思考,并培养学生聚焦关键问题进行辩证思考的连续性设计思维方式。
Teaching Practice and Reflection on Research-based Planning and Design:A Perspective of "Urban-Water Coupling"
Authors: 王 世福 , 曾 祥诚 , 张 晓阳
Published: January 2024

为改善传统城乡规划设计教学实践中研究与设计脱节问题,强化规划研究与规划设计形成有效合力,华南理工大学建筑学院教学团队结合“十三五”国家重点研发计划课题《城市新区水环境系统与规划设计优化技术》研究,以“城水耦合”视角开展研究型规划设计教学实践工作。截至目前,已完成两期城市总体规划、四期毕业设计的本科教学工作,并培养了多位博硕士研究生。
The Campus and the City: A Design Revolution Explained
Authors: 赫伯特 迈克尔
Published: January 2024

这篇关于设计史的文章思考了城市大学的建筑和景观最近在设计方法上的转变。基于二次文献和已发表的校园总体规划,本文将20世纪中期对城市与校园分离的关注和当代对城市与校园融合的探索进行了对比研究。虽然主要借鉴的是欧洲和美国的例子,但这一话题是普适的。文章从3个尺度对校园设计革命进行了探讨和解释,首先是大学的城市环境尺度,其次是校园布局和景观尺度,最后是建筑及其功能尺度。每一个尺度都为追求知识的目标找到了一个设计要素。
Towards a Dialectical Openness: Thoughts on the Openness of University Campus
Authors: 刘 玉龙 , 祝 远
Published: January 2024

本文在以开放校园问题为视角梳理大学校园建筑发展历程的基础上,以“开放性”及其3个维度为理论框架,提出未来大学校园建筑走向“非简单开放”的设计策略和相应空间模式。
"from genesis, formation, to identity”:Planning and design of the Xi'an Academy of Fine Arts, Chang'an Campus Xi'an Academy of Fine Arts
Authors: 华 承军 , 文 学艺
Published: January 2024

通过对西安美术学院长安校区校园规划设计3个阶段的演变分析,文章提出了在地性、地域性、文化性3个因素在营造校园独特文化意境方面的重要作用,并结合实际案例提出在具体过程中立意导向的设计策略。
Efektivitas Media Video Persalinan terhadap Pengetahuan Proses Persalinan pada Ibu Primigravida
Authors: Aprilia Della , Desmarnita Ulty , Nurhaeni Heni
Published: January 2024

Primigravida memiliki ketakutan yang meningkat semakin dekatnya waktu persalinan, dikarenakan kurangnya pengetahuan apa yang akan terjadi selama proses persalinan serta adanya cerita mengenai proses persalinan yang menakutkan. Pendidikan kesehatan dapat meningkatkan pengetahuan dengan bantuan media edukasi yang memiliki peran sebagai penyalur informasi salah satunya adalah media video. Tujuan penelitian ini adalah untuk mengetahui efektivitas penggunaan media edukasi video persalinan terhadap peningkatan pengetahuan proses persalinan pada ibu primigravida. Penelitian ini menggunakan desain penelitian quasi experiment pre-posttest dengan kelompok kontrol. Analisis data menggunakan uji Wilcoxon dan Mann U Whitney. Instrumen penelitian yang digunakan kuesioner. Sampel dihitung menggunakan teknik purposive sampling dengan total sampel 108 responden. Hasil penelitian didapatkan nilai p-value 0,0001(α