bluuebunny/crossref_metadata_2025 huggingface dataset:
Percutaneous treatment of simple renal cysts with 24-h-interval ethanol sclerotherapy
Authors: Karakas Hakki Muammer , Yildirim Gulsah
Published: March 2023

Abstract Objective: To investigate the efficacy of 24-h interval multiple-session ethanol sclerotherapy for the treatment of simple renal cysts. Materials and Methods: The study sample included 58 patients (mean age, 65.37 ± 11.95 years). We included 76 simple renal cysts that were treated with percutaneous aspiration with a minimum of two sessions of 95% ethanol sclerotherapy in a 24-h interval between sessions. Patients were evaluated at 1, 3, and 6 months after the intervention for the efficacy of the treatment. Treatment success was defined as a complete regression of a cyst or a > 50% reduction in its volume, with no recurrence of symptoms. Results: The mean preprocedural cyst size was 72.98 ± 25.14 mm, and the mean preprocedural cyst volume was 205.76 ± 244.15 mL. The mean volume of ethanol used in the first sclerotherapy session was 62.76 ± 30.71 mL. The mean fluid accumulation in the cysts at the end of the first 24-h interval was 4.66 ± 7.13 mL. The mean quantity of ethanol used in the second sclerotherapy session was 26.48 ± 22.2 mL. A third sclerotherapy session was required in only 10 (13.2%) of the cysts. The mean follow-up period was 52.84 ± 37.83 months. The rate of complete regression was 97.4% for the whole sample at the end of the follow-up. Conclusion: Ethanol ablation with 24-h intervals is a safe and effective treatment option in the minimally invasive percutaneous treatment of simple renal cysts.
Primary hypothyroidism due to thyroid carcinoma in a feline
Authors: Brum Isabela de Andrade , Mario Fabiana Goés , Lúcio Bruna Marquardt , Mariga Carollina , Amaral Anne Santos do , Filho Saulo Tadeu Lemos Pinto
Published: March 2023

ABSTRACT: Hypothyroidism is rarely observed in cats. This article reports the case of a thirteen-year-old feline with a one-year history of bilateral cervical swelling that had majorly grown in size two weeks prior to the animal’s admission. The cat presented with dysphonia, lethargy, weight gain, and constipation. On physical examination, hypothermia was observed, with a rectal temperature of 36.5 ºC. Fine-needle aspiration cytology suggested thyroid neoplasia. The serum levels of total T4 and thyroid stimulating hormone (TSH), along with the exclusion of non-thyroid diseases, confirmed the diagnosis of hypothyroidism. This is the first report of feline hypothyroidism in Brazil secondary to thyroid neoplasia, classified as a follicular-compact carcinoma and confirmed by histopathology.
Analysis of virome by high-throughput sequencing disclosed multiple infection in a single grapevine plant
Authors: Fajardo Thor Vinícius Martins , Nhani Júnior Antonio , Nickel Osmar
Published: March 2023

ABSTRACT: Among phytosanitary problems of the grapevine, viruses stand out for their capacity of reducing the quality and yield of grapes. However, detecting and identifying viral infections in grapevines can be challenging. This study performed a high throughput sequencing (HTS) of the viral pathogens present in a vine showing virus-like symptoms to elucidate the etiology. HTS analysis reported in a hybrid grapevine with mild curling down of leaf edges, the presence of four viruses and viroids, which were probably implicated in the observed symptoms. The determined complete genomes showed high genetic identities with previously characterized isolates of homologous pathogens.
Quem somos nós e quem são eles? Transformações históricas da violência na relação homem-animal à luz de expressões artísticas
Authors: Frota Renata , Casotti Leticia Moreira
Published: March 2023

Resumo Este estudo investiga o percurso das transformações da violência presente na relação homem-animal, em múltiplos períodos do tempo, recorrendo a expressões artísticas, de forma a trazer contribuições para esta temática. O estudo utiliza uma abordagem multidisciplinar dos campos das Artes, História e Filosofia buscando contribuições à literatura de marketing e comportamento do consumidor. A análise crítica visual é a metodologia utilizada na análise de seis obras de artes de diferentes períodos históricos e compreensão da relação homem-animal no tempo. Os achados sugerem formas de violência que estão presentes nessa relação e se transformam. A pesquisa desafia o domínio da discussão sobre a relação homem-animal no campo do marketing, circunscrita a experiências positivas com animais de companhia; traz interpretações dos caminhos da violência na relação homem-animal ao longo do tempo para melhor compreender significados e práticas do presente; adiciona elementos visando discussões e reflexões, necessárias a pesquisadores e profissionais de marketing, sobre a relação homem-animal e violência.
A flexibilização do trabalho como regra no capitalismo: conceituação e proposições teórico-analíticas
Authors: Tessarini Junior Geraldo , Saltorato Patrícia , Rosa Kaio Lucas da Silva
Published: March 2023

Resumo O objetivo deste artigo é explorar a temática da flexibilização do trabalho no contexto do capitalismo flexível, com vistas a propor um modelo teórico-analítico das diferentes classificações desse fenômeno. A partir de uma literatura de cunho crítico, apresentamos como questão fundamental a compreensão sobre quais são as múltiplas manifestações de flexibilidade e como elas afetam os trabalhadores e suas práticas produtivas. Buscando aventar o debate, o modelo proposto compreende 3 níveis analíticos interdependentes: flexibilidade contratual, flexibilidade funcional e flexibilidade espaço temporal. Cada nível apresenta 2 subcategorias que permitem classificar e analisar uma atividade de trabalho quanto a formas de vínculo, remuneração, conteúdo, autonomia, local de execução e duração. Ao longo do ensaio, apresentamos uma definição alternativa ao conceito de flexibilização do trabalho e defendemos que se trata de um fenômeno incompatível com o aprimoramento do processo de trabalho em favor dos trabalhadores, representando mais um movimento de acirramento do conflito capital versus trabalho. Configura-se, portanto, num mecanismo de exploração dos trabalhadores e de ampliação da produtividade da força de trabalho em busca de maior acumulação privada de capital.
Estimation of fat mass in Southern Brazilian female adolescents: development and validation of mathematical models
Authors: Cintra-Andrade Joaquim Huaina , Ripka Wagner Luis , Leite Neiva , Ulbricht Leandra
Published: March 2023

abstract This study aimed to develop and validate the first mathematical models, based on anthropometric properties, to estimate fat mass (FM) in a heterogeneous sample of female adolescents. A cross-sectional and quantitative study conducted with 196 individuals aged 12 to 17 years from the metropolitan region of Curitiba, Paraná, Brazil. The participants were randomly divided into two groups: regression sample (n = 169) and validation sample (n = 27). Dual-energy X-ray absorptiometry (DXA) was used as the reference method to determine body fat in relative and absolute values. Stature, body mass, waist girth and triceps, subscapular, biceps, iliac crest, abdominal, front thigh and medial calf skinfold thickness were defined as independent variables and measured according to an international technical protocol. Statistical analyzes used the Ordinary Least Square (OLS) regression model, paired t test and Pearson correlation. Four multivariate mathematical models with high determination coefficients (R2 ≥90%) and low estimated standard errors (SEE = ≤2.02 kg) were developed. Model 4 stands out for its low number of independent variables and significant statistical performance (R2 = 90%; SEE = 1.92 kg). It is concluded that the four mathematical models developed are valid for estimating FM in female adolescents in southern Brazil.
Content validation of a questionnaire to assess the knowledge of pediatricians, family, and community physicians on obesity
Authors: Domingos Daniel Servigia , Troster Eduardo Juan , Vieira Teresa Cristina Alfinito
Published: March 2023

ABSTRACT Objective: The aim of this study was to validate the content of a questionnaire in order to assess the attitudes and practices in childcare consultations, knowledge on overweight and obesity, their risk factors, and barriers in addressing the issue by pediatricians and family physicians. Methods: The Delphi technique was used, with the objective of reaching a consensus on a certain subject, through experts’ opinions. The content validity index (CVI) of each item, axis, and questionnaire was calculated. The inter-rater reliability was calculated using an agreement coefficient suitable for the answer distribution such as Gwet's AC2 with ordinal weight. Results: A total of 63 experts were invited to assess and give their opinion on the questionnaire. In all, 52 accepted the invitation and analyzed the instrument. After two rounds, the questionnaire reached the proper CVI for the study and was considered complete, with its final version having 40 questions, a final index of 95%, and an inter-rate reliability of 0.905. Conclusions: This instrument, developed to assess attitudes and practices, knowledge, and barriers found in addressing the obesity by primary care physicians, obtained a CVI greater than 0.8 and an excellent agreement coefficient of the 52 judges. Therefore, its content can be considered validated.
Implementation of a standardized handoff system (I-PASS) in a tertiary care pediatric hospital
Authors: Soares Deydson Rennan Alves , Rodrigues Dalma , Carmona Fabio
Published: March 2023

Abstract Objective: The handoff is the act of transferring information and responsibility among healthcare providers, and it is critical for the patient safety and the quality of service. The aim of this study was to evaluate the implementation of a standardized medical handoff system [I-PASS (Illness severity, Patient summary, Action list, Situation awareness and contingency planning, Synthesis by receiver)] and assess the effect on the amount and quality of the information transmitted during medical handoffs in a pediatric ward. Methods: In a prospective intervention study, physicians (staff and residents) who work in 12- or 24-h shifts in the pediatric ward of a single tertiary care Brazilian hospital were eligible. Those who agreed to participate were trained in an online session (lecture plus simulation). Medical handoffs were recorded pre- and post-intervention (training) to compare the amount and quality of information transmitted in handoffs. Results: The handoff standardization significantly increased the number of relevant information delivered for 12 out of the 16 items assessed without increasing, in seconds, the handoff duration (45.9 vs. 48.0; p=0.349). The protocol training and the following discussion about communication resulted in greater focus and attention among participants during transfers, decreasing time spent with interruptions and communication unrelated to the patient (18 vs. 2.7%). Regarding the I-PASS elements, there was an increase in the number of action lists and contingency plans reported (31 vs. 81% and 16 vs. 73%, respectively; p<0.001 for both). Conclusion: Standardization brought greater efficiency and objectivity to handoffs. It increased the quantity and quality of the information transmitted while successfully drawing attention to the most important points.
Osmopriming with selenium: physical and physiological quality of tomato seeds in response to water deficit
Authors: Silveira Alice de Souza , Pinheiro Daniel Teixeira , Oliveira Rafael Macedo de , Dias Denise Cunha Fernandes dos Santos , Silva Laércio Junio da
Published: March 2023

Abstract: Tomato is a crop sensitive to water deficit and the responses of seeds to germination under these conditions involve biochemical, physiological, and molecular processes. The aim of this study was to evaluate the physical, physiological, and biochemical changes in tomato seeds osmoprimed with selenium (Se) and subjected to water deficit during germination. Tomato seeds of the LA 4050 and LA 3475 accessions were osmoprimed with PEG 6000 solution (-1.0 MPa) plus Na2SeO4 (12.5 μM) or only with PEG 6000 solution for 24 h or unprimed. The seeds from the different treatments were subjected to water deficit (-0.3 MPa) or to control (0 MPa). Image analyses were performed (X-ray), physiological variables were obtained by the germination test and activities of SOD, CAT and POX enzymes were determined. Osmopriming, especially with PEG, provided the seeds of both accessions with higher densities and gray mean when compared to unprimed ones. Seeds under water deficit showed lower physiological performance and lower enzymatic activity. Se did not induce seed resistance to water deficit. Osmopriming with PEG 6000 at -1.0 MPa is an efficient technique for improving the physiological quality of seeds of tomato accessions susceptible and tolerant to water deficit. Moreover, the antioxidant enzyme CAT proved to be an indicator of oxidative stress tolerance in tomato seedlings under water deficit.
The evaluation of university professors: a look from the students
Authors: Valentín-Martínez Bilda , Mayor-Ruiz Cristina
Published: March 2023

Abstract The main objective of this article is to analyze the perception that students have of the professor evaluation system in their universities. Although in most universities in the Dominican Republic the evaluation is done by coordinators, professors and students, in this study the situation is investigated based on the results analyzed in the opinions of 347 students from different disciplines of the Education career of seven higher education institutions in this country. Thus, a questionnaire of open ended and closed ended questions is applied, which makes it possible to verify the level of satisfaction that these actors have in the professor evaluation process. The participating population is selected by means of a non-probabilistic, incidental casual method, directly choosing the participants of the fifth, sixth, seventh, eighth and ninth semesters. The results indicate that students consider it of great value to be taken into account in the evaluation process of their professors, who appreciate the level of reliability of the application of the evaluation instrument; but that the evaluation could be improved by taking into account other components that do not appear in it and integrating open-ended questions, which allow them to express their opinions more accurately. The results are relevant for the design of a new professor evaluation system.
JORNALISMO E LITERATURA REMODELADOS: ESTUDO DE UM GRUPO DE INTELECTUAIS DAS CAMADAS MÉDIAS (1940-1960)
Authors: Queler Jefferson José
Published: March 2023

RESUMO Neste artigo, analiso as trajetórias dos jornalistas-escritores Nelson Rodrigues, Carlos Heitor Cony, Antonio Callado, Clarice Lispector, Fernando Sabino e Otto Lara Resende. Oriundos dos setores médios, esses intelectuais se lançaram na profissão de escritor em contexto de maior autonomização dos campos teatral e literário em relação à imprensa, entre as décadas de 1940 e 1960. Nesse quadro, é possível que a produção ficcional deles esteja relacionada às estratégias de seu grupo social, compostas por relações tanto modernas quanto tradicionais, para evitar rebaixamentos sociais e impulsionar sua ascensão no âmbito do jornalismo e das letras em geral.
MATHEMATICAL MODELING OF ACOUSTIC WAVE PROPAGATION IN ELASTIC MATERIALS WITH MULTI-PERIODIC HIERARCHICAL STRUCTURE OF HETEROGENEITIES
Authors: Savatorova Viktoria L. , Talonov Alexey V.
Published: March 2023

An asymptotic homogenization procedure is applied for acoustic wave propagation in a heterogeneous elastic medium with a multi-periodic hierarchical structure of heterogeneities. We assume the existence of two periodic cells with characteristic sizes l2 and l1, respectively. The ratio ε = l2/l1 is considered to be small and of the same order of magnitude as the ratio l1 /L, where L is the macroscopic characteristic size of a system. The solution of the problem will be largely determined by the relation between the wavelength λ and the characteristic sizes of the system. For the case when λ/l1 ~ 1, we derive a homogenized macroscopic equation for the displacement and obtain approximations to the displacement and frequency. Several illustrative examples are considered to show the effect of peculiarities of the structure on two different spacial scales on energy distribution in the propagating wave.
COMBINED DATA AND DEEP LEARNING MODEL UNCERTAINTIES: AN APPLICATION TO THE MEASUREMENT OF SOLID FUEL REGRESSION RATE
Authors: Georgalis Georgios , Retfalvi Kolos , Desjardin Paul E. , Patra Abani
Published: March 2023

In complex physical process characterization, such as the measurement of the regression rate for solid hybrid rocket fuels, where both the observation data and the model used have uncertainties originating from multiple sources, combining these in a systematic way for quantities of interest (QoI) remains a challenge. In this paper, we present a forward propagation uncertainty quantification (UQ) process to produce a probabilistic distribution for the observed regression rate r. We characterized two input data uncertainty sources from the experiment (the distortion from the camera Uc and the non-zero-angle fuel placement UY), the prediction and model form uncertainty from the deep neural network (Um), as well as the variability from the manually segmented images used for training it (Us). We conducted seven case studies on combinations of these uncertainty sources with the model form uncertainty. The main contribution of this paper is the investigation and inclusion of the experimental image data uncertainties involved, and how to include them in a workflow when the QoI is the result of multiple sequential processes.
Evaluation of sediment management strategies for Tarbela reservoir
Authors: Rashid Muhammad Usman , Miqdad Haris , Saad ul Hassan Muhammad , Haseeb Abdul , Asad Muhammad
Published: March 2023

Globally, multipurpose large dams play significant roles by providing water for irrigation, flood control and hydropower. This study aims to evaluate different strategies for the evacuation of deposited sediments in Tarbela reservoir by using Hydrologic Engineering Center-River Analysis System. Sediment flushing from existing power tunnels was found infeasible due to the downstream constraints and the loss of hydropower. New sediment bypass tunnels on the right-side bank of the dam to overcome the constraints were analysed. The sediment balance ratio, long-term capacity ratio and economic analysis were computed along with sediment modelling for different scenarios. The most technically viable scenario was 90 days flushing at 390 m drawdown level with a discharge of 5000 m3/s. This scenario was not economically feasible in terms of net present value, internal rate of return and the benefit cost ratio. The upstream under construction Diamer Basha dam was also evaluated. The results suggested a large volume of sediment would be trapped in the upstream reservoir, which would ultimately lead to a significant reduction in the inflow of sediment and the delta movement in the Tarbela reservoir. This option was recommended due to its multiple benefits and potential capacity to enhance Tarbela reservoir's life.
Compressive performance and stress–strain relationship of geopolymer recycled brick aggregate concrete
Authors: Zheng Yong-Qian , Zheng Li-Ya , Wang Yu-Qing
Published: March 2023

Geopolymer recycled brick aggregate concrete (GRC), a new type of environmentally friendly material, can reduce carbon dioxide emissions and effectively utilise construction waste. To study its basic compressive performance and stress–strain relationship, cubes and prisms of GRC and ordinary recycled brick aggregate concrete (ORC) under five recycled brick aggregate (RBA) replacement ratios (0, 25, 50, 75 and 100%) were tested compressively. The failure mode, working performance, compressive strength, elastic modulus, Poisson's ratio and other indexes as well as the full stress–strain curves were obtained. The test results show that with the increase of RBA replacement ratio, the compressive strength and modulus of elasticity of GRC and ORC decrease, and the slump, strain corresponding to peak stress, transverse deformation coefficient and Poisson's ratio increase. Compared with ORC, under the same water-to-binder ratio, GRC exhibits 29% to 52% smaller elastic modulus, more than 30% reduction in slump, close Poisson's ratio and steeper decline branch of compressive stress–strain curve. Moreover, the RBA replacement ratio has a greater effect on GRC. Based on the uniaxial compressive model of ordinary concrete, the compressive constitutive models suitable for GRC and ORC are proposed.
A Study of the Role of an Input-Based Speech Community in the TV Series, Good Witch
Authors: Chung Yunjeong
Published: March 2023

The purpose of the paper is to study EFL students’ reaction toward the concept of a speech community reflected in a TV series. Three non-English major students were recruited for the study. Each student was provided with four different drama clips which represent four different speech communities. Speech communities provide L2 learners with linguistic and cultural knowledge that helps people socialize with others (Schmid, 2016). After the participants went through L1 translation activities which helped them to increase their awareness of what an L2 speech community is, the participants were given two tests (memorization and selection of relevant expressions) and one written interview. The results indicated that the speed of all three participants’ memorization was better after the given instruction and they also selected more expressions on the interview test. In the written interview, all the participants showed positive attitudes about the use of a speech community. Such results have potential pedagogical implications in EFL classrooms. First, the use of a speech community brings abundant context to the relevant scene to help memorization, and provides salience to expressions; consequently EFL students can pick up desirable expressions. Second, the concept of speech community can integrate both cultural and language matters simultaneously. Details will be discussed further in the paper.
The Use of Silver Nitrate as an Elicitor to Increase Bioactive Compounds in Artichoke [Cynara cardunculus var. scolymus (L.) Fiori] Callus Culture
Authors: ÖZSAN KILIÇ Tuğçe , ONUS Ahmet Naci
Published: March 2023

The globe artichoke belongs to the Asteraceae family and has become more and more popular among other vegetables due to its beneficial health-promoting features that are related to bioactive compounds present in leaves. The plant materials have inadequate proportions of valuable bioactive compounds in nature, so researchers are emphasizing on how to enhance their amounts. In vitro techniques with integrated novel practices can be employed to enhance phytochemicals from any plant. The current study aimed to determine and assess valuable bioactive components in 3 artichoke cultivars via callus cultures which were subjected to a treatment of 4 different concentrations (2.5, 5.0, 10.0, and 15.0 mg L-1) of silver nitrate. Results indicated that well-balanced levels of plant growth regulators were necessary for stimulating the callus formation of globe artichoke. The findings of the current study also revealed the importance of cultivar differences regarding callus formation. Experimental results revealed that variation in silver nitrate concentrations had a significant effect on biomass, total phenolic content and total antioxidant activities. The results of the current, study may offer a good strategy by promoting bioactive compounds of globe artichoke leaves for utilizing in large-scale industries, pharmacology, and food supplements.
FELAKET HABERLERİNİ KAYDIRMA ÖLÇEĞİ TÜRKÇE FORMUNUN GEÇERLİK VE GÜVENİRLİK ÇALIŞMASI
Authors: ANLI Gazanfer
Published: March 2023

Bu çalışmanın amacı, Felaket Haberlerini Kaydırma Ölçeğinin Türkçe formunun psikometrik özelliklerinin incelenmesidir. Çalışma, Google formlar aracılığı ile ulaşılan, 88'i (%29,5) erkek, 210'u (%70,5) kadın olmak üzere 298 yetişkinden oluşmaktadır. Çalışmada ölçüt geçerliği için Öz-Kontrol Ölçeğinden faydalanılmış ve iki ölçek arasında orta düzeyde anlamlı bir korelasyon tespit edilmiştir. Kapsam geçerliği adımında uzman görüşü alınmıştır. Ölçeğin yapı geçerliği için gerçekleştirilen doğrulayıcı faktör analizi sonucunda 15 maddelik tek faktörlü yapının iyi uyum gösterdiği belirlenmiştir. Ölçekteki maddelerin faktör yükleri en düşük .49, en yüksek .85 olup, ölçeğin madde toplam korelasyonları en düşük .51, en yüksek .77 olarak bulunmuştur. Alt ve üst %27’lik iki grup arasındaki farklılık istatistiksel olarak anlamlıdır. Ölçeğin güvenirlik analizinde Cronbach Alfa kat sayısı .92 olarak tespit edilmiştir. Güvenirlik analizine ek katkı olarak gerçekleştirilen çift yarılar yönteminde, eşdeğer yarılar arasındaki korelasyon kat sayısı .82 olarak hesaplanmıştır. Sonuç olarak bu ölçeğin, yetişkinlerde felaket haberlerini kaydırma düzeylerini tespit etmek için yetkin bir ölçme aracı olduğu anlaşılmıştır.
JAMES CLARENCE MANGAN’IN TÜRK EDEBİYATI MAKALELERİ ÜZERİNE BİR İNCELEME
Authors: KOÇYİĞİT Fırat Ender , KARACA Nesrin
Published: March 2023

James Clarence Mangan, on dokuzuncu asır başlarında İrlanda’da yaşamış, İrlanda’nın milli şairliği mertebesine yükselmiş bir sanatçı ve aydındır. Mangan’ı Türk okuru için ilgi çekici kılan şey ise onun bir Türk dostu olması, genel olarak Şark, özel olarak da Türk kültürü, sanatıyla yakından ilgilenmesidir. İrlanda dışına hiç çıkmayan Mangan, Joseph Freiherr von Hammer-Purgstall’ın Almanca çevirileri üzerinden Osmanlı şiiri ile tanışmıştır. Mangan, Osmanlı şiirine dair izlenimlerini Dublin University Magazine dergisinde, “Literae Orientales” başlığını taşıyan altı makalede İngiliz ve İrlandalı okurlarla buluşturmuştur.

Bu makalede Türkiye’de daha önce Mangan’ı konu edinen çalışmalar kısaca özetlendikten sonra Mangan’ın Türk şiirini ele alan altı makalesi incelenmiş ve Mangan’ın görüşleri değerlendirilmiştir. Mangan’ın makalelerinde zaman zaman gerçeklikten kopmasına karşın Türk edebiyatına olumlu yaklaşmasının, Türk edebiyatı üzerine çalışmaları teşvik etmesinin, Türk edebiyatı unsurlarını Batı şiirine taşımasının değerli kazanımlar olduğu sonucuna varılmıştır.
DOĞA TEMELLİ TURİZME KATILAN TURİSTLERİN SEYAHAT MOTİVASYONLARINI VE YAŞAM DOYUMLARINI BELİRLEMEYE YÖNELİK BİR ARAŞTIRMA
Authors: ÇAVUŞOĞLU Fatih , KOLBAKIR Ercan Selim
Published: March 2023

Günümüzde, pandeminin de etkisiyle, özel ilgi turizminin bir çeşidi olarak doğa temelli turizme yönelik artan bir ilginin olduğunu söylemek mümkündür. İnsanlar artık sağlıkları açısından riskli gördükleri kalabalık ortamlardan uzaklaşarak, sessiz ve sakin bir doğa ortamında vakit geçirmeye yönelik bir eğilim göstermektedirler. Bu kapsamda, doğa temelli turizme katılım gösteren bireylerin seyahat motivasyonlarını ve yaşam doyumlarını ortaya koymak önemli görülmektedir. Bu araştırmanın temel amacı, doğa temelli turizme katılan bireylerin seyahat motivasyonlarını ve yaşam doyumlarını ortaya koymaktır. Araştırma kapsamında kasti örnekleme yöntemi kullanılarak 263 bireyden veri elde edilmiştir. Araştırma kapsamında edinilen verilere tanımlayıcı analizler, faktör analizi, güvenirlik analizi, t testi analizi ve ANOVA analizleri uygulanmıştır. Analiz sonuçlarına göre bireyleri doğa temelli turizme katılmaya iten başlıca faktörlerin; doğa ile buluşma, kaçış ve rahatlama, yenilik arama ve iyi vakit geçirme oldukları tespit edilmiştir. Bireyleri doğa temelli turizm destinasyonlarına çeken başlıca faktörlerin ise doğa, sakinlik ve destinasyon imkanları olduğu belirlenmiştir. Doğa temelli turizme katılan bireylerin yaşam doyumu düzeylerinin ise ortalamanın nispeten üzerinde olduğu bulunmuştur.
KÜÇÜK VE ORTA ÖLÇEKLİ İŞLETMELERDE ISO 9001:2015 KALİTE YÖNETİM SİSTEMİ UYGULAMALARININ DEĞERLENDİRİLMESİ: KAYSERİ İLİ ÖRNEĞİ
Authors: KAPUCUGİL İKİZ Aysun , DÖNEN Fırat
Published: March 2023

Bu çalışmanın amacı, özellikle en son sürümüyle gelen yenilikler çerçevesinde, ISO 9001:2015 Kalite Yönetim Sisteminin (KYS) KOBİ’lerde ne derece etkin uygulandığını araştırmak ve sistemin uygulanmasına yönelik zorlukları ortaya koymaktır. Çalışmada, Kayseri’de faaliyet gösteren 22 KOBİ’de ISO 9001:2015 KYS uygulamaları incelenerek, standarttaki yeni kavram ve konulara uyum sağlama durumları, karşılaştıkları uygunsuzluklar ve uygulamada yaşadıkları zorluklar özelinde değerlendirmeler yapılmıştır . Bu kapsamda, araştırmanın güvenirliğini doğrulayacak şekilde verileri toplamak için, önceden tanımlı bir görüşme protokolü izlenerek görüşmeler gerçekleştirilmiştir. Yarı yapılandırılmış soru formu aracılığı ile elde edilen nitel veriler, tanımlayıcı istatistikler ve içerik analizi yöntemi ile bulgulara dönüştürülmüştür. Çalışmada KOBİ’lerin ISO 9001:2015 standardının şartlarına uyumu açısından firma ölçeğine göre farklılaşan uygulamalar görülmüştür. KOBİ’lerin büyüklüğü arttıkça ISO 9001 standardında yapılan değişikliklere verilen tepkiler olumlu karşılanmış ve uygulamaların etkinliği artmıştır. Daha çok kalite yönetim sisteminde süreç yaklaşımının uygulanması, liderlik ve taahhüt, yetkinlik, farkındalık, iç denetim ve risk ve fırsatları belirleme ile ilgili uygunsuzlukların yaşandığı gözlenmiştir. KOBİ’lerde standardın uygulanmasını zorlaştıran faktörler arasında, ISO 9001 standardındaki kavramların kişilerce farklı yorumlanabilmesi, çok fazla dokümantasyon gerektirmesi, çalışanların standardın önemini bilmemesi, motivasyon eksikliği, standart ile ilgili eğitimlerin yetersizliği ilk sıralarda yer almıştır. Çalışma, KOBİ yöneticilerine, uygulayıcılara ve araştırmacılara ISO 9001:2015 KYS şartlarının uygulanmasına ilişkin önemli sonuçlar sunmaktadır.
Noticing of Secondary School Mathematics Teachers on Physical and Psychological Violence
Authors: ÖZDEMİR BAKİ Gülşah , KARAKUŞ UMAR Esra
Published: March 2023

The increase in the number of violence can be associated with raising awareness about violence, defining and recording types of violence, or the presence of push factors that cause violent behavior to emerge. However, violence has become more visible in social life with the more frequent use of the media. The aim of this study is to reveal the noticing of secondary mathematics teachers on the types of violence. For this purpose, four video segments representing the types of physical and psychological violence were watched by seven secondary school mathematics teachers working in different regions of Turkey. Written opinions of the teachers about the types of violence they noticed in the video sections were taken and semi-structured interviews were conducted with the teachers based on these opinions. The data obtained were analyzed with the content analysis technique and the opinions of the teachers were classified under three categories as "recognized types of violence", "defining the type of violence noticed" and "reaction to the type of violence". The analyzes revealed that the participating teachers generally recognized physical violence in the video sections they watched, but they had difficulties in recognizing and defining psychological violence. Although the reactions of the participating teachers about the types of violence they have developed awareness of, they preferred to remain unresponsive. Considering the importance of the reaction in preventing violence, it is suggested that in-service trainings will contribute to raising teachers' awareness of the types of violence.
Phage infection and timed harvest of E. coli and B. subtilis cells v1
Authors: Athukoralage Januka
Published: March 2023

This protocol outlines how to infect E. coli and B. subtilis with phage T4 and SPO1, respectively, and harvest cells at set time points. Harvesting cells at different timepoints during infection allows you to evaluate when bacteriophage transcripts are most abundant in cells and maximize their enrichment for downstream analyses such as chemical analysis and RNA sequencing.
Choanoflagellate Ciliogenesis Live Imaging v2
Authors: C Coyle Maxwell
Published: March 2023

This protocol removes the cilia/flagella from choanoflagellate cells and sets up the cells for live imaging of ciliogenesis. It has been developed for the species Salpingoeca rosetta, but may be portable into other choanoflagellate species. Cells begin to re-generate their cilia/flagella right after removal. The idea of using a cold shock with glycerol for ciliary removal came from Brokaw et al 1960 (doi: 10.1016/0014-4827(60)90027-6).
Calculating multiplicity of infection (MOI) v1
Authors: Athukoralage Januka
Published: March 2023

This is a simple protocol for the calculations that we routinely do to determine phage multiplicity of infection (MOI) in our experiments. It's really important to know what MOI you are using. Ideally, you would perform these quantifications before your experiments such that you have a good ballpark understanding of what your multiplicity of infection is in your experiment. This also allows you to prepare phage dilutions to more precisely hit your target MOI. We will also sometimes plate out bacteria and phage day-of using our experimental samples to give us an exact measurement of our MOI based on the culture that we used and to double-check that our phage dilution was correct.
Sağlık Bilimleri Öğrencilerinin Koronavirüs-19’a Yönelik Bilgi Düzeyleri ve Sağlık Davranışlarına Etkisinin İncelenmesi
Authors: TANRIVERDİ Seher , KESKİN Hülya , ÇİFTÇİOĞLU Gülcan
Published: March 2023

Amaç: Araştırmanın amacı sağlık bilimleri öğrencilerinin COVID-19 salgını ile ilgili bilgi düzeylerini saptamak ve sağlık davranışları üzerindeki etkisini
incelemektir.
Gereç ve Yöntemler: Çalışma, çevrimiçi anket yöntemi ile bir üniversitenin Sağlık Bilimleri Fakültesi ve Sağlık Hizmetleri Meslek Yüksekokuluna kayıtlı
345 öğrenci ile yapılmıştır. Çalışma verileri, Ocak-Şubat 2021 tarihlerinde çevrimiçi anket formu kullanılarak toplanmıştır. Anket formu katılımcıların
demografik özelliklerine dair soruların yanı sıra sağlık bilgi düzeyi; COVID-19 salgınına yönelik sağlık davranışına etkisi olmak üzere 24 sorudan oluşmak-
tadır. Veri analizinde, tanımlayıcı istatistik testleri ile sayı, yüzde dağılımları, ortalama ve standart sapma değerleri hesaplanmıştır. Grup içi ortalamalarının
karşılaştırılmasında One-Way Anova testi kullanılmıştır.
Bulgular: Çalışmaya katılan öğrencilerin yaş ortalaması 21.65±3.35 olup %79.7’si kadındır. Katılımcıların %74.21’i 2019 yılı öncesinde COVID-19 hak-
kında bilgisinin olmadığını, %91.3’ünün kendisi veya ailesinden birilerinin COVID-19’a yakalanma konusunda endişe duyduğunu belirtmiştir. Öğrencilerin
%86.37’si pandemi sürecinin bulaşıcı hastalıkları önlemeye yönelik aşı uygulamaları konusunda farkındalık kazandırdığını, %63.2 ‘si pandemi sürecinde
ellerini yıkama süresinde değişiklik olduğunu, %76.8’i televizyon kanallarında yer alan haberlerden bilgi edindiğini bildirmiştir. COVID-19 öncesi-sonrası
günlük uyku, sıvı alımı gibi sağlık davranışları arasında istatistiksel olarak ileri düzeyde anlamlı farklılık olduğu saptanmıştır (p<0,001).
Sonuç: Sonuç olarak, COVID-19 pandemi süreci sağlık bilimleri öğrencilerinin bilgi düzeylerinde ve sağlık davranışlarında değişiklikler meydana get-
irmiştir. Sağlık bilimleri öğrencilerinin pandemi süreci yönetimi konusunda önemli bir yeri olduğu için konu ile ilgili daha fazla çalışma yapılıp literatüre
katkı sağlanması önerilmektedir.
Resistencia a la proteína C activada: una nueva causa de trombofilia
Authors: Torres Hernández José Domingo
Published: March 2023

El tromboembolismo venoso es un problema médico serio que causa mucho sufrimiento y en ocasiones la muerte. Hay factores de riesgo circunstanciales: Cirugía, inmovilización, embarazo y uso de contraceptivos orales. Hay además factores gen éticos de riesgo: Deficiencias de las proteínas C y S, antitrombina III y disfibrinogenemia. Recientemente se encontró la resistencia hereditaria a la acción anticoagulante de la proteína C activada como factor implicado en la patogénesis. En la mayoría de los casos es causada por una sola mutación en el gen del factor V. En este artículo se describen la base molecular de la mutación, las manifestaciones clínicas, los métodos de diagnóstico y las guías de manejo.
Análisis espectral de la variabilidad de la frecuencia cardíaca
Authors: Gallo Villegas Jaime A. , Farbiarz Farbiarz Jorge , Álvarez Montoya Diego Luis
Published: March 2023

En los últimos años, se ha reconocido la relación existente entre el funcionamiento del sistema nervioso autónomo (SNA) y la mortalidad cardiovascular. Esto ha motivado la búsqueda de marcadores cuantitativos del balance autonómico. La Variabilidad de la Frecuencia Cardíaca (VFC) representa uno de los más promisorios. La VFC se define como la variación que ocurre en el intervalo de tiempo entre latidos consecutivos y se ha propuesto que su comportamiento depende de la modulación autonómica, así como sus implicaciones en la mortalidad cardiovascular. Para evaluar la VFC se analiza el tacograma (registro de frecuencia cardíaca en el tiempo). El estudio de la VFC comenzó hace 30 años, aproximadamente, y ha ganado mayor importancia en los últimos 10 años. Existen varios métodos para evaluar la VFC. Los más aceptados actualmente son los métodos en el dominio de la frecuencia (análisis espectral). El análisis espectral consiste en descomponer el tacograma, el cual se asemeja a una onda compleja, de manera que se obtienen los componentes espectrales, y se encuentran componentes de alta frecuencia (HF), relacionados con el tono parasimpático, uno de baja frecuencia (LF), relacionado con la modulación tanto simpática como parasimpática y otro de muy baja frecuencia (VLF), el cual no se ha relacionado con el SNA. Los métodos del dominio del tiempo, son básicamente estadísticos y evalúan la variabilidad por medio de promedios y desviaciones estándar. Son los más conocidos, pero al parecer tienen menos ventajas que los métodos espectrales. La VFC se correlaciona con adaptaciones fisiológicas a cambios en el medio interno, externo y a la presencia de enfermedades. En este artículo se explican los principales métodos en el dominio de la frecuencia y del tiempo y la relación que tiene la VFC con las adaptaciones fisiológicas y con enfermedades específicas.
Las quimioquinas: citoquinas proinflamatorias y reguladoras del tráfico celular
Authors: Cano Londoño Nancy Fanory , Montoya Guarín Carlos Julio
Published: March 2023

Las quimioquinas constituyen un grupo numeroso de citoquinas proinflamatorias; hasta el momento se han caracterizado alrededor de 40 quimioquinas diferentes que provienen de variadas fuentes celulares y tienen acciones muy pleiotrópicas. Su estudio ha despertado gran interés debido a la selectividad que tienen para activar y dirigir el tráfico de diferentes subpoblaciones de leucocitos, a diferencia de otros factores quimiotácticos que atraen por igual a los neutrófilos y monocitos. Adicionalmente, se ha observado que las quimioquinas están involucradas en la hematopoyesis, angiogénesis, morfogénesis tisular, crecimiento tumoral y apoptosis. Debido a que las quimioquinas orquestan la migración y función de los leucocitos, se ha propuesto que cumplen un papel muy importante en la fisiopatología de algunas enfermedades como la glomerulonefritis inducida por inmunocomplejos, la isquemia reperfusión, la ateroesclerosis, la infección por el VIH y algunas reacciones autoinmunes.
Calidad de vida y calidad de vida relacionada con la atención en salud
Authors: Lugo Agudelo Luz Elena , García García Héctor Iván , Gómez Restrepo Carlos
Published: March 2023

Se revisan los conceptos existentes sobre calidad de vida en general y Calidad de vida relacionada con la salud. La primera, entendida como lo que hace que una vida sea mejor, a partir de teorías hedonistas, de satisfacción de preferencias y de los ideales de una buena vida. Se discuten términos como bienestar, capacidades, preferencias, autodeterminación y autonomía, en sus conexiones con la calidad de vida. La Calidad de vida relacionada con la salud, se define como el componente de la Calidad de vida en general que se debe a las condiciones de atención en salud de las personas y que se refiere a partir de las experiencias subjetivas de los pacientes sobre su salud global. Su relevancia es tanto ética, en la toma de decisiones médicas, como en el desarrollo de medidas que evalúen los resultados de intervenciones..
Planungsfunktionen für (Energie-)Speicher
Authors: Reinpold Lasse , Wagner Lukas , Kilthau Maximilian , Karmann Alexandra , Fay Alexander
Published: March 2023

Mit steigender Energiegewinnung aus erneuerbaren Energien kommt Speichersystemen eine zunehmend wichtige Bedeutung zu. Die notwendigen  Planungsfunktionen für den automatisierten,  wirtschaftlichen und ökologischen Betrieb von Speichern sind Fokus dieses Beitrags. Zunächst werden diese  Funktionen beschrieben, und es werden Anforderungen an sie hergeleitet. In einer Fallstudie wird ein einfaches  Beispiel einer Planungsfunktion in Form eines  mathematischen Optimierungsmodells verwendet, um Strom möglichst günstig und emissionsarm an der  Intraday-Strombörse einzukaufen. Die Kosten und  Emissionen des Stromeinkaufes lassen sich durch den  Einsatz von Speichern in der betrachteten Fallstudie  signifikant reduzieren, wobei sich auch zeigt, dass das  Einsparpotenzial für Speicher mit Größen von über vier  Betriebsstunden zunehmend abflacht.
Conflictos culturales en las relaciones de pareja en adolescentes de origen marroquí en el sureste español
Authors: Cala Verónica C. , Soriano-Ayala Encarnación
Published: March 2023

Las relaciones sentimentales en los adolescentes de origen extranjero suponen un proceso de negociación entre valores, normas y prescripciones de dos sociedades, pudiendo generar a conflictos culturales. Este estudio analiza las narrativas acerca de las relaciones de pareja y las tensiones culturales y religiosas que se generan en 25 estudiantes de origen marroquí, entre 15-19 años. Los resultados revelan una comprensión de las relacionales heterogénea, pero mayoritariamente liberal, donde prima la virtualidad y la inestabilidad, en las que persisten valores familiares marroquíes. Se describe una diversidad de discursos respecto al amor y la pareja, aunque se mantiene el matrimonio, la monogamia y la fidelidad. Los jóvenes musulmanes, mayoritariamente varones, mantienen una visión positiva hacia los celos ligada a una cultura del honor. Manifiestan una construcción del género en la pareja en conflicto entre formas liberales y tradicionales en las mujeres marroquíes, mientras que los varones expresan formas de masculinidad tradicional. Asimismo, declaran conflictos culturales y religiosos sobre (1) la sexualidad, especialmente en lo relativo a la virginidad; y (2) en la concepción de los roles de género en la pareja y la violencia machista dentro de la familia. En estos aspectos se observa un triple choque cultural: intrafamiliar, con la comunidad de origen y con la comunidad española. Estos aspectos deben considerarse para la adaptación transcultural de los programas de prevención de la violencia en la pareja.
Retos y posibilidades de los centros de primaria ante los efectos de la segregación escolar temprana
Authors: Bianchi Calero Daniel , Cabrera Leopoldo
Published: March 2023

Este artículo estudia las posibilidades de los centros educativos para afrontar los efectos de la segregación escolar temprana en España. Se analiza la relación entre el proceso organizativo y pedagógico de los centros educativos y la composición social de su alumnado y su impacto relativo en los resultados en matemáticas de los estudiantes de cuarto curso de educación primaria. Contamos para ello con una muestra representativa para España de 9555 alumnos-as, 602 profesores-as y 501 centros educativos que procede del archivo de microdatos del informe TIMSS 2019, publicado por la IEA.  Se constata la existencia de correlaciones estrechas entre los factores del proceso escolar y las características socioeconómicas del alumnado en diferentes tipos de escuela en función de la heterogeneidad social de su alumnado y el grado en que concentran a estudiantes procedentes de entornos desfavorecidos. Se confirma, asimismo, un efecto menos intenso de la organización y la enseñanza sobre los resultados educativos en comparación con el efecto de la composición social, si bien no es posible descartar la incidencia de determinadas formas organizativas y pedagógicas para la mejora de los resultados educativos en las escuelas afectadas por los procesos de segregación escolar.
Optimising Characteristics of an Intelligent Transport System Using a Real-Coded Genetic Algorithm Based on Adaptive Mutation
Authors:   Central Economics and Mathematics Institute RAS, Moscow, Russian Federation, Akopov A. S. , Beklaryan L. A. ,   Central Economics and Mathematics Institute RAS, Moscow, Russian Federation, Beklaryan A. L. ,   HSE University, Moscow, Russian Federation
Published: March 2023

A novel real-coded genetic algorithm (FCGA-AM) that uses the proposed adaptive mutation (AM) operator is presented. The algorithm is designed to optimise the characteristics of the developed intelligent transportation system. The performance of the proposed genetic algorithm was evaluated in comparison with other methods of multicriteria heuristic optimization with the use of various test instances and well-known quality metrics for Pareto frontiers. At the next stage, the FCGA-AM was applied to find the best road safety trade-offs involving unmanned ground vehicles (UAVs) interacting with conventional ground vehicles (UTVs), pedestrians and other agents
A Machine Learning Approach for Transmitted Power Estimation in Power Beaming Systems
Authors:   S. P. Korolev Rocket and Space Corporation ", Kapranov V. V. ,   Energia",   , Korolev, Moscow region, 141070, Russian Federation, Tugaenko V. Yu. ,   S. P. Korolev Rocket and Space Corporation "Energia", Korolev, Moscow region, 141070, Russian Federation
Published: March 2023

Currently, predictive machine learning methods are used in many areas of life — from traffic predictions to medical diagnosis. Recently, these approaches also appeared in atmoposheric studies, first of all, for estimation of turbulence parameters, these tasks are necessary for a qualitative solution of atmospheric optical communication issues. The purpose of this work is to show the possibility and prospects of using machine learning algorithms for estimation transmitted power in power beaming systems in real time under changing atmospheric conditions. Experimental data were collected over several months on long atmospheric experimental setup, among gathered data there are such meteorological parameters as pressure, temperatures, wind speed, humidity, dew point, wind direction, solar flux. The data was collected for several locations. The power of the incident radiation was estimated from the voltage on the photovoltaic receiver. The nearest neighbors method, gradient boosting and neural networks were used as machine learning algorithms, the algorithms were compared with each other in terms of the average absolute error (MAPE) and the coefficient of determination (R2). The analysis of the results showed a good predictive ability of all models and potential of using even on the basis of simple meteorological measurements. The use of traditional methods requires much more complex measurements, such as scintillometry, or empirical approximations are used. Machine learning makes it possible to get results with only integral meteorological parameters and shows good accuracy for arbitrary conditions. Gradient boosting with R2 0.951 and MAPE 0.020 on all data was chosen as the best model. The results of this model was interpreted using the SHAP method, the dependence of the result on the input data is consistent with expectations.