bluuebunny/crossref_metadata_2025 huggingface dataset:
Robot Manipulator Pelontar Bola Pingpong Berbasis APP Inventor Dan Bluetooth
Authors: Hasad Andi , Musaffa Ali , Paronda Abdul Hafid , Bakri Muhammad Amin
Published: February 2022

Ping pong ball throwers are used as automatic ball shooters as a method of self-training and training the skills of professional athletes. By adding wireless communication, ping pong ball throwers can be controlled remotely. The controller interface is created using the App Inventor so that controllers can be carried out via smart phones. To get the ball throwing “service” required a combination of parameter values of the speed of the ejection motor and the angle of the servo motor.
Analisis Voltage Drop Pada Jaringan Tegangan Rendah Dengan Metode Pecah Beba Pada Gardu KH 007 Di PT PLN (Persero) UP3 Pamekasan
Authors: Hajar Ibnu , Pasra Nurmiati , Rusmansyah Denny
Published: February 2022

In the operation of the electric power system, good quality service is needed. One of them is thevoltage value received by the customer does not get a voltage drop. Based on SPLN No.1: 1978, theservice voltage is a maximum of 5% and a minimum of 10% of the nominal voltage of the LowVoltage Network that is 220 Volt. One of the locations experiencing voltage drop problems is on theCentral Pakandangan Village, Sumenep. Based on an analysis do by the PT PLN UP3 PamekasanNetwork division, it turns out that the voltage drop that occurred on Central Pakandangan Villagecaused by the location. The location is to far from the KH 007 distribution substation, which is 643meters. Then, the area around the location also has a high burden due to the many standingresidential settlements. Therefore, it is necessary to break the load on the network. This method isdone by moving or transferring part of the load from the old network to the new network. Which isthe last 5 poles in this line. so the load supported by one line does not have voltage drop. The resultobtained after performing the load break is that the voltage on the receiving side rises to phase R200 Volt, phase S 212 Volt, and phase T 202 Volt. Where previously the value of the voltage on thereceiving side is phase R 189 Volt, phase S 206 Volt, and phase T 194 Volt.
Rancang Bangun Sistem Pemadam Kebakaran Box Panel Outdoor Menggunakan Arduino Uno Berbasis GSM SIM800L V1
Authors: Fisabili Lanina Milenise , Oktaviana Putri Tri Wahyu
Published: February 2022

With the installation of electrical installations on the panel box, there is a risk of interference causing fires caused by electricity due to short circuits, burning cables due to poor insulators and MCBs being burned due to overload. So we need a fire extinguishing system on the panel box that can minimize the risk of a large fire and can be monitored remotely. The extinguishing system consists of Arduino Uno as a microcontroller to process data, Infrared sensor KY-026 and temperature sensor DS18B20 as input to detect fire and excess temperature in the box panel. The MG995 Servo Motor and buzzer are used as outputs for the APAR drive and provide early warning. GSM SIM800L V1 as a remote communication to provide notifications to cell phones when fires and excessive temperatures occur. The test results in this study is a fire extinguishing system with KY-026 Infrared sensor which is able to detect fire at an angle of 60°. The DS18B20 temperature sensor detects a temperature of 41°C indicating overheating, as well as the MG995 Servo Motor rotates 90° and the buzzer sounds an alarm then the GSM SIM800L V1 sends a notification remotely which is 1210 meters or even more.
Efisiensi Panel Surya Kapasitas 100 Wp Akibat Pengaruh Suhu Dan Kecepatan Angin
Authors: Dahliya Dahliya , Samsurizal Samsurizal , Pasra Nurmiati
Published: February 2022

Solar radiation has a great effect on the output of the photovoltaic system. Wind speed is directly related to the cooling of the PV system and can also affect the performance of the solar collector. This research looks at the influence of temperature and wind on the efficiency of solar panels. From the results of the tests and calculations, it was found that the temperature of the single crystal panel measured on that day was 44°C, and the temperature of the polycrystalline panel was 43°C. The effect of wind speed on the efficiency of the solar module, calculated based on calculations using the linear regression method, shows a correlation level of R = 0.0281. This means that only about 2.81% wind speed will affect it. Has solar module efficiency. From the various aspects of the calculations carried out, we can see that the efficiency of the single crystal panel is 11.716%, while the efficiency of the polycrystalline panel is 10.02%. From the calculation results, we can conclude that the efficiency of the single crystal module is significantly increased.
Perancangan Alat Bantu Swing Otomatis Untuk Mengurangi Kegagalan Produk Pada Industri Bahan Bangunan
Authors: IPM Pawenary , Sitorus Meyhart , Aziz Hastuti
Published: February 2022

Kegagalan produk adalah kondisi suatu produk yang tidak sesuai dengan maksud atau tujuan yang diinginkan. Pengendalian kegagalan produk merupakan suatu sistem verifikasi dan penjagaan/ perawatan dari suatu tingkatan kualitas produk atau proses yang dikehendaki. Tujuan dari penelitian ini adalah untuk mengetahui metode yang tepat untuk digunakan dalam perancangan dan pemasangan alat bantu agar mengurangi kegagalan produk. Selain itu penelitian ini memberikan gambaran mengenai perbaikan alat bantu swing otomatis agar produk yang terbuang dapat dimanfaatkan lebih maksimal, sehingga perusahaan dapat meningkatkan keuntungannya. Dari studi literatur didapatkan perancangan dan redesign untuk perbaikan alat bantu ini baik menggunakan dua metode, yaitu : Focus Group Discussion dan Quality Function Development. Selanjutnya alat bantu swing otomatis dianalisis dan hasilnya ia dapat dijadikan sebagai salah satu alternatif yang bisa membantu perusahaan mengurangi biaya produksi dan meningkatkan keuntungan perusahaan. Penggunaan sensor proksimitas yang mampu mendeteksi kontak fisik dapat digunakan untuk memudahkan perancangan swing otomatis tersebut. Dengan digunakannya solenoid valve pneumatic, menjadikan alat tersebut bekerja dengan lebih baik.
Pengujian Analisis TeganganTembus Minyak Transformator 60 MVA Di GIS Kebun Jeruk
Authors: Rahayu Sofitri , Okvasari Rudina , Diantari Retno Aita
Published: February 2022

Minyak transformator berfungsi sebagai isolasi dan pendingin, juga mempunyai sifat dapat melarutkan gas-gas yang timbul akibat kerusakan sistem. Penggunaan transformator dimanapun adalah sama, khususnya untuk tranformator daya, yaitu sebagai penaik atau penurun tegangan menyesuaikan tegangan dari mesin itu sendiri. Dengan melakukan perawatan secara berkala dan pemantauan kondisi transformator pada saat beroperasi akan banyak keuntungan yang didapat, antara lain: meningkatkan keandalan dari transformator tersebut, memperpanjang masa pakai, jika masa pakai lebih panjang, maka secara otomatis akan dapat menghemat biaya penggantian unit transformator. Adapun langkah-langkah perawatan transformator salah satun ya adalah pemeriksaan berkala kualitas minyak isolasi. Tujuan dari penelitian ini adalah untuk menganalisis karakteristik dari minyak transformator yang dilakukan pemeriksaan secara berkala di Gardu Induk dengan nilai standar nilai tegangan tembus menurut SPLN’50-1982 dan IEC No. 56 tahun 1991 adalah sebesar ≥30 kV/2,5 mm. Dari hasil pengujian dapat diketahui bahwa nilai rata-rata tegangan tembus minyak trafo 2 sebesar 23,7 KV/2,5 mm dan nilai-nilai rata-rata tegangan tembus minyak trafo 3 sebesar 32,7 KV/2,5 mm. Sehingga dapat dilakukan analisa bahwa untuk tegangan tembus minyak trafo 2 di bawah 30 kV/2,5 mm yang artinya minyak trafo sudah harus dilakukan penanganan lebih lanjut. Sedangkan untuk minyak trafo 3, nilainya diatas di bawah standar 30 kV/2,5 mm yang artinya minyak tersebut masih baik untuk digunakan.
Studi Laju Penurunan Frekuensi Pada Sistem Kelistrikan Sumatera Bagian Utara Dengan Skema Pelepasan Beban
Authors: Diantari Retno Aita , Rafsanjani Muhammad
Published: February 2022

PT PLN (PERSERO) is a company engaged in electricity in Indonesia and plays a role in the generation and distribution of electricity to consumers. PLN has quality standards that must be met, one of which is a stable frequency even though  the load keeps changing all the time. In electric power systems, the frequency value is an indicator of the balance  between active power generated with a total load of active system power  and losses. The frequency value  will increase if there is an excess generation and conversely the frequency value will decrease if there is a shortage of generation or overload. If there is a disturbance that  causes the large capacity generating unit to be release from the systems (trip), in this case the PLTU Pangkalan Susu and PLTU Nagan Raya will cause a decrease in frequency so that the Northern Sumatera  interconnection system is  disrupted. A large decrease in frequency can lead to failure of generating units in a row so that it can cause total system failure (blackout). To avoid a total system failure (blackout) a load shedding scheme with under frequency relay (UFR) is carried out. This research is done by experimental methods. According to this research, it’s been found that the setting of under frequency relay conducted by PLN UP2B Northern Sumatera is good, in this sense of blocking the system from blackout due to a massive power trip.
La capilla del Hospital de Santiago en Úbeda a través del estudio tridimensional de su sección
Authors: Estepa Rubio Antonio , Estepa Rubio Jesús , León Torres Javier
Published: February 2022

Presentamos, en este artículo, una revisión de la propuesta de Vandelvira para la capilla del Hospital de Santiago en Úbeda, entendida como unidad con autonomía suficiente para poder establecer sobre ella un estudio comparado con otras obras de naturaleza sacra, igualmente resueltas por este genial arquitecto.

Las singularidades espaciales, geométricas y constructivas de este fragmento arquitectónico, integrado en un sistema de mayor envergadura formal y funcional, nos permiten generar una reflexión profunda sobre la sistemática proyectual desarrollada por el maestro.

El estudio minucioso de la sección del edificio, en relación con el análisis sobre la morfología de las techumbres, ponen de manifiesto la excepcionalidad de la solución; sobre todo, cuando comprendemos las razones que motivan la disyunción abrupta que se planifica entre las identidades de los espacios interiores y exteriores.
Yáñez, A. y Rodríguez Temiño, I. ¿Cuánto valen los platos rotos? Teoría y práctica de la valoración de bienes arqueológicos
Authors: Pérez Muncunill Patricia
Published: February 2022

En esta reseña se pretende ofrecer información sobre este libro titulado ¿Cuánto valen los platos rotos? Teoría y práctica de la valoración de bienes arqueológicos . Expondremos de forma breve cuáles son los contenidos principales y secundarios de este libro que trata sobre el valor del patrimonio arqueológico. También sobre lo importante que es saber valorar y asignar un valor correcto y de forma totalmente ordenada y sistemática a estos bienes arqueológicos que son tan importantes para nuestra sociedad.
Investigadores de universidades ibero-americanas idean una plataforma colaborativa de estudio de los paisajes hitóricos de la producción
Authors: Larive López Enrique
Published: February 2022

El laboratorio americano de los paisajes históricos de la producción (applab), iniciativa auspiciada por la Universidad de Sevilla y la Asociación Universitaria Iberoamericana de Postgrado AUIP, surge como plataforma colaborativa de mediación entre investigadores, estudiantes, agentes y ciudadanos que investigan, habitan, gestionan o intervienen en territorios industriales históricos activos o en obsolescencia en América y la Península Ibérica. Inicialmente applab cuenta con la participación de 46 investigadores y el respaldo de 22 instituciones académicas e investigadoras y pretende ofrecer un espacio de experimentación creativa que permita la transferencia simultánea de conocimiento aplicado a la sociedad.
Un mapa colaborativo para documentar y difundir los sistemas de regadíos históricos de Granada y Almería
Authors: Martín Civantos José María , Toscano Maurizio , Bonet García María Teresa , Correa Jiménez Elena
Published: February 2022

El mapa colaborativo de regadíos históricos es una iniciativa que nace en 2015 desde el Laboratorio de Arqueología Biocultural (MEMOLab) de la Universidad de Granada para la visibilización de estos espacios productivos y las comunidades de regantes que los gestionan. Es una labor de documentación y puesta en valor en la que es fundamental la participación ciudadana, resaltando la implicación de las escuelas e institutos. Hasta la fecha cuenta con 585 acequias digitalizadas y 834 espacios de regadío localizados. Sin embargo, en palabras de sus creadores, “se trata de un proyecto en construcción, que espera ir perfeccionándose hasta llegar a ser un referente para el conocimiento y difusión de los regadíos históricos”. Por el momento se ha centrado en las provincias de Granada y Almería, que concentran la gran mayoría de estos espacios.
En marcha un estudio sobre los procesos de patrimonialización de la cultura de frontera en el sur ibérico
Authors: Hernández León Elodia
Published: February 2022

Se denomina Patrimonio Cultural y Memoria de fronteras en el Sur Ibérico y es un proyecto liderado por el grupo de investigación out_arquías, con componentes de las universidades de Pablo de Olavide y de Sevilla. Comenzó a ejecutarse a principios de 2020 y tiene prevista una duración de tres años. La investigación se centra en los procesos de patrimonialización de la frontera que se dan en los municipios limítrofes andaluces con el Alentejo portugués en la actualidad, atendiendo al papel relevante que adquiere el patrimonio inmaterial al mismo tiempo que advierte sobre el riesgo de una excesiva banalización en su puesta en valor.
Jiménez-Esquinas, G. Del paisaje al cuerpo: la patrimonialización de la Costa da Morte desde la antropología feminista
Authors: Rubio Coronado Samuel , Gregorio Gil Carmen
Published: February 2022

Reseña del libro Jiménez-Esquinas, G. (2021) Del paisaje al cuerpo: la patrimonialización de la Costa da Morte desde la antropología feminista
El IAPH planifica una segunda edición del MOOC Patrimonio cultural de Andalucía
Authors: Romero Moragas Carlos
Published: February 2022

El curso en línea, masivo, gratuito y abierto (MOOC) Patrimonio cultural de Andalucía organiza nueva convocatoria este año 2022. Es una iniciativa del Instituto Andaluz del Patrimonio Histórico (IAPH), en colaboración con el Instituto Andaluz de Administración Pública (IAAP). Este curso va dirigido, por una parte, al personal no especializado en patrimonio cultural dentro de las administraciones públicas, y, por otra, está abierto a toda la ciudadanía interesada en el patrimonio cultural de Andalucía. La primera edición del MOOC se celebró entre el 28 de abril y el 2 de junio de 2021 y se matricularon un total de 1.337 personas.
FİNK’İN ANLAMLI ÖĞRENME YAKLAŞIMI VE HAYAT BİLGİSİ ÖĞRETİM PROGRAMI KAZANIMLARININ FİNK TAKSONOMİSİNE GÖRE SINIFLANDIRILMASI
Authors: YAĞAN Saadet Aylin
Published: February 2022

Bu araştırmanın amacı, Fink’in anlamlı öğrenme yaklaşımı hakkında bilgi vermek ve Hayat Bilgisi dersi öğretim programı kazanımlarının Fink taksonomisine göre dağılımını incelemektir. Araştırmada, nitel araştırma yaklaşımı benimsenmiştir. Araştırma yöntemi doküman incelemesidir ve veriler yönteme uygun olarak doküman inceleme tekniği ile toplanmıştır. Verilerin analizinde Fink taksonomisinden yararlanılmıştır. Bu taksonomi; temel bilgi, uygulama, sentez, insani boyut, önem verme ve öğrenmeyi öğrenme alanlarından oluşmaktadır. Taksonomideki öğrenme alanları arasında hiyerarşik bir ilişki bulunmamaktadır. Hayat bilgisi 1., 2. ve 3. sınıf öğretim programlarında yer alan 148 kazanım Fink taksonomisine göre sınıflandırılmıştır. Araştırmanın güvenirliği için uzman görüşüne başvurulmuştur. Bulgulara göre 1. sınıf hayat bilgisi öğretim programında en fazla kazanım uygulamayla ilgiliyken, en az kazanım öğrenmeyi öğrenmeyle ilgilidir. 2. sınıf öğretim programında en fazla kazanım önem vermeyle, en az kazanım insani boyuta ilişkilidir. 3. sınıf öğretim programında en fazla kazanım sentezle, en az kazanım insani boyutla ilgilidir. Genel olarak hayat bilgisi öğretim programında en fazla kazanım uygulamayla en az kazanım ise insani boyutla ilişkilidir.
The HIV Patient and their Antibody Response to SARS-CoV-2 Infection
Authors: Stout Robert L. , Rigatti Steven J.
Published: February 2022

SARS-CoV-2 infected HIV patients have a similar antibody response to infection as age and sex-matched controls. Well, HIV patients previously infected with COVID-19 have a similar rate of infection and antibody response as age and sex-matched controls.
Knowledges, Attitudes and Practices of Diabetic Patients Face to Diabetic Retinopathy in Parakou in 2019
Authors: Rodrigue Abel Assavedo Codjo , Amadou Issifou Alfa Bio , Zabdi Sina , Salimatou Monteiro , Chakiratou Abouki , Soule Alamou , Sidonie Tchabi Hounnou
Published: February 2022

Introduction: Diabetic retinopathy is one of the main causes of blindness. Preventive measures and screening will reduce its impact. Objective: Study the knowledges, attitudes and practices of diabetic patients about diabetic retinopathy from 03 hospitals in the District of Parakou in 2019. Methods: The study was carried out in 03 hospitals in northern Benin (University and Regional Health Center of Borgou and Alibori, Army Health Center of Parakou, and the Diabetes Center of Benin. This was a descriptive and analytical cross-sectional prospective study that covered a period of 03 months from 15th May to 20th August, 2019. The sampling method was non-probability. Selection of diabetic patients was exhaustive taking care for the consent of each patient. The aged group was at least 18 years old and above, resident in Parakou and followed up in one of the above heath centers. We enrolled 150 patients after submitted them to some questionnaires. Results: From the total number of 150 patients, 59.33% were male. The mean age was 55.07 ± 11.62 years. The participants were predominantly married (87.33%) and 62% of them were literate. 48% of patients said diabetes mellitus is responsible of eye complications. 52% and 12% of patients reported that balancing blood sugar and normalizing blood pressure, respectively, are preventative factors for diabetic retinopathy. 27.33% of patients reported the need for a regular eye fundus exam. 12.67% of patients have a regular annual eye fundus examination and 56.67% of patients have never had one. Education and gender were associated with level of knowledges; education and low income were associated with level of practices. Conclusion: Reducing the impact of diabetic retinopathy requires better involvement of the diabetic patient, the ophthalmologist, the endocrinologist and the authorities of the Ministry of Health.
Protecting the Corneal Endothelium during Cataract Surgery Using the Anterior Capsulorhexis Flap as a Corneal Protection Shield
Authors: Kristina Stjepanek , Nino Hirnschall , Sahand Amir-Asgari , Julius Hienert , Oliver Findl
Published: February 2022

Purpose: Classification and quantification of swirling lens fragments during phacoemulsification with or without using the capsulorhexis flap as an additional endothelial protective shield. Also, to determine the effects on endothelial cell count (ECC) and central corneal thickness (CCT) caused by fragments during cataract surgery. Methods: Patients with dense cataracts scheduled for surgery were randomized into study and control groups (2:1). In the study group, the anterior capsule ‘flap’ from the capsulorhexis was used as an endothelial protection shield during phacoemulsification. The control group underwent standard surgery. During surgery, intra-operative optical coherence tomography was performed to score swirling lens fragments that hit the corneal endothelium. CCT and ECC were measured at several time points before and after surgery. Results: In total, 176 fragments in 49 eyes of 49 patients came in contact with the corneal endothelium. The mean number of fragments was 2.8 in the study group and 4.8 in the control group. There was no statistically significant change of ECC between the groups. Mean CCT increased by 16.6 µm in the study group and by 42µm in the control group 1 day postoperatively. There was no significant difference between the groups regarding the increase in CCT. Conclusions: No significant benefit concerning ECC or CCT was found in the study group compared to the control group, meaning that we were not able to prove that using the capsulorhexis flap as a protection shield is a sufficient method of protecting the corneal endothelium.
Up-Dated the Critical Issues of Corneal Cross-Linking (Type-I and II): Safety Dose for Ultra-Thin Cornea, Demarcation Line Depth and the Role of Oxygen
Authors: Lin Jui-Teng
Published: February 2022

Purpose: To update analytic formulas for the overall efficacy of corneal collagen crosslinking (CXL) including both type-I and oxygen-mediated type-II mechanisms, the role of oxygen and the initiator regeneration. Also, to derive the formulas for the minimum corneal thickness and demarcation line depth. Study Design: Modeling the kinetics of CXL in UV light and using riboflavin as the photosensitizer. Place and Duration of Study: New Taipei City, Taiwan, between June, 2021 and July, 2021. Methodology: Coupled kinetic equations are derived under the quasi-steady state condition for the 2-pathway mechanisms of CXL. For type-I CXL, the riboflavin (RF) triplet state [T] may interact directly with the stroma collagen substrate [A] to form radical (R) and regenerate initiator. For type-II process, [T] interacts with oxygen to form a singlet oxygen [1 O2 ]. Both reactive radical (R) and [1 O2 ], can relax to their ground state, or interact with the substrate [A]) for crosslinking. Based on a safety dose, formulas for the minimum corneal thickness and demarcation line depth (DLD) are derived. Results: Our updated theory/modeling showed that oxygen plays a limited and transient role in the process, in consistent with that of Kamave. In contrary, Kling et al believed that type-II is the predominant mechanism, which however conflicting with the epi-on CXL results. For both type-I and type-II, a transient state conversion (crosslink) efficacy in an increasing function of light intensity (or dose), whereas, its steady state efficacy is a deceasing function of light intensity. RF depletion in type-I is compensated by the RF regeneration term (RGE) which is a decreasing function of oxygen. For the case of perfect regeneration case (or when oxygen=0), RF is a constant due to the catalytic cycle. Unlike the conventional Dresden rule of 400 um thickness, thin cornea CXL is still safe as far as the dose is under a threshold dose (E*), based on our minimum thickness formula (Z*). Our formula for thin cornea is also clinically shown by Hafez et al for ultra thin (214 nm) CXL. Conclusion: For both type-I and type-II, a transient state conversion (crosslink) efficacy in an increasing function of light intensity (or dose), whereas, its steady state efficacy is a deceasing function of light intensity. CXL for ultra thin corneas are still safe, as far as it is under a threshold dose (E*), based on our minimum thickness formula, which has a similar tend as that of demarcation line depth. the type-II efficacy also provides the survival rate for the treatment of corneal keratitis.
THE IMPLEMENTATION OF EDUCATIVE VALUES THROUGH THE BUGINES’S FALSAFAH TO INCREASE IN LEARNING OUTCOMES OF THE ISLAMIC AND KEMUHAMMADIYAHAN
Authors: Elihami Elihami
Published: February 2022

The study of the application of educative values ​​to Bugis philosophy expressions is a learning concept that helps educators aim to link between local wisdom material and Al-Islamic and Kemuhammadiyahan material. The formulation of the problem is how to apply the educational value of Bugis philosophy expressions in Al-Islam and Kemuhammadiyahan subjects to first semester PLS students at STKIP Muhammadiyah Enrekang and the first semester PLS student learning outcomes at STKIP Muhammadiyah Enrekang through the application of educational values ​​to the Bugis philosophy? The activities carried out were the real world situation of students and encouraged students to make connections between modern knowledge possessed and their application in the era of industrial revolution 4.0 challenges in family and community life. The research method implemented is qualitative descriptive research. The collection of research data using observation methods, documentation methods, and interview methods. The results of the research obtained indicate that the application of educational values ​​of philosophical expressions is very effective to be applied in the lecture process. The results of the research achieved were Al-Islam and Kemuhammadiyahan subjects through the application of philosophical values ​​of philosophical expressions, there was an increase in the achievement of the learning outcomes of the STKIP Muhammadiyah Enrekang School of Education students significantly.
EXISTENCE OF WITNESSES IN MARRIAGE ACCORDING TO HADIST PERSPECTIVE
Authors: Rahmawati Rahmawati , Elihami Elihami
Published: February 2022

A marriage contract is analogous to a sale and purchase agreement, then women are free or have the right to make a marriage contract, as women are free and have the right to enter into a contract of sale and purchase. Thus, women have the free right to make a marriage contract because there is no legal difference between contracts. In a marriage contract, although guardians have rights, they are not absolute. Guardians can only exercise their absolute trust rights if there is an error made by the woman in doing so or marrying an unequal male. It is said so because of the mistake of women in making a marriage contract, will also cause disgrace on his guardian in the future.
The characteristics teaching materials of biology laboratory management
Authors: Saifuddin Much Fuad , Puspitasari Etika Dyah
Published: February 2022

The suitable teaching materials will make it easier for students to learn in the classroom. To present suitable teaching materials, a needs analysis is needed. This study aimed to determine the types and characteristics of teaching materials needed in learning biology laboratory management. The survey method was carried out to students who were randomly selected. The instrument is arranged in the form of a questionnaire by paying attention to each characteristic indicator of various teaching materials. The validity of the instrument used a combination of expert judgment. The questionnaire is distributed via google form to students who have taken laboratory management courses with a filling period of 2 weeks obtained 123 respondents. The data were analyzed descriptively of quantitatively and qualitatively. The results showed that the percentage of students who needed teaching materials for biology laboratory management lectures was 98%; the characteristics of teaching materials wanted by students included: containing learning objectives, using simple language, sequenced materials according to lecture sessions, containing summaries, and providing feedback. Teaching materials based on existing characteristics can be in the form of modules that are adapted to the Semester Learning Plan.
Developing of character science teaching tools integrated with the value of Qur'an for junior high school students
Authors: Irwansyah Muhammad , Perkasa Magfirah , Muchlis Muchlis , Bakhtiar Bakhtiar , Azmin Nikman
Published: February 2022

The curriculum of 2013 places spiritual attitudes as the first competencies from core competencies and social attitudes as the second. This indicates that a spiritual and social attitude is needed to survive in the 21st century. Therefore, this study was held with the aim to develop science teaching materials with integrated character of the Qur'anic verses that valid and effective criteria. The type of research that used in this research is adapted from Thiagarajan’s developing model which focused on defining, designing, and developing stages. The instruments used are validation sheets for expert judgement and student response questionnaires to collect spiritual character of the students. Based on the results of the study, the science teaching materials with Islamic character interpretations meet the valid criteria with the validity of RPP = 3.37, modules = 3.23 and LKS = 3.51. Meanwhile, based on the results of limited trials, it can be concluded that the students' responses to science teaching materials with integrated character of the Qur’anic verse are in the positive and very positive category.
The diversity of Pteridophytes in pepe watershed Surakarta polluted by household waste
Authors: Salsabila Nadia , Ramadhani Rina Wahyu , Mumpuni Kistantia Elok
Published: February 2022

Pepe River is one of the Bengawan Solo with a reasonably high level of water pollution due to the habit of the surroundings in throwing garbage into the river. Plants that can survive in polluted land conditions have a high tolerance level, called pioneer plants. One of them is ferns (Pteridophyta). This study aims to identify the type, abundance, Important Value Index (IVI), and index Diversity of pteridophytes plant diversity in the Pepe Watershed. The method used in this research is descriptive quantitative using the quadrat sampling technique method with a 1x1 meter plot. The sampling technique is using purposive sampling. Data analysis was conducted qualitatively and quantitatively. Analysis of diversity index data (H’) by Shannon-Wiener. Based on the results of the study found eight species of ferns from 5 families. There are Pteris vittata, Pteris biaurita L., Adiantum lunulatum Burm.fil., Adiantum latifolium Lam., Adiantum hispidulum Sw, Marsilea crenata C. Presl, Microlepia speluncae (L.) T. Moore, and Asplenium scandicinum Kaulf. This diversity is included in the medium category with H'= 1.44. The fern with the highest abundance was Pteris vittata with 176 individuals, a density of 5.87 individuals/m2, a frequency of 0.53, and an IVI of 109.3%. Set side by set, the lowest abundance was Microlepia speluncae with eight individuals, a density of 0.27 individuals/m2, a frequency of 0.03, and IVI of 5.6%. Based on this, ferns can survive in polluted river areas. Information on the diversity of ferns found on critical land, especially rivers, is expected to provide initial information in overcoming other similar critical lands.
Klasyfikacja technologiczna wyrobów krzemiennych ze stanowiska 4 w Bęble, pow. krakowski / Technological classification of flint artefacts from Site 4 in Bębło, Kraków district
Authors: Trela-Kieferling Elżbieta
Published: February 2022

The flint collection from Site 4 in Bębło, the Kraków district, consists of more than 8,800 artefacts preserved in their entirety or in fragments: precores, cores, distinctive items, tools (including typological tools produced from debitage, mining tools, fragmentarily retouched items, and hammers), blades, flakes and a small number of chunks. Both approaches: chaîne opératoire and dynamic classification, have been used to analyse the assemblages. The chapter includes 21 figures, 35 tables and 64 plates that document and show results of the analysis of the material.
Conplastic strains for identification of retrograde effects of mitochondrial dna variation on cardiometabolic traits in the spontaneously hypertensive rat
Authors: Pravenec M , Šilhavý J , Mlejnek P , Šimáková M , Mráček T , Pecinová A , Tauchmannová K , Hütl M , Malínská H , Kazdová L , Neckář J , Kolář F , Žurmanová J , Novotný J , Houštěk J
Published: February 2022

Mitochondrial retrograde signaling is a pathway of communication from mitochondria to the nucleus. Recently, natural mitochondrial genome (mtDNA) polymorphisms (haplogroups) received increasing attention in the pathophysiology of human common diseases. However, retrograde effects of mtDNA variants on such traits are difficult to study in humans. The conplastic strains represent key animal models to elucidate regulatory roles of mtDNA haplogroups on defined nuclear genome background. To analyze the relationship between mtDNA variants and cardiometabolic traits, we derived a set of rat conplastic strains (SHR-mtBN, SHR-mtF344 and SHR-mtLEW), harboring all major mtDNA haplotypes present in common inbred strains on the nuclear background of the spontaneously hypertensive rat (SHR). The BN, F344 and LEW mtDNA differ from the SHR in multiple amino acid substitutions in protein coding genes and also in variants of tRNA and rRNA genes. Different mtDNA haplotypes were found to predispose to various sets of cardiometabolic phenotypes which provided evidence for significant retrograde effects of mtDNA in the SHR. In the future, these animals could be used to decipher individual biochemical components involved in the retrograde signaling.
DIGITAL ELEVATION MODEL ANALYSIS FOR DAM SITE SELECTION USING GIS
Authors: Zomrawi Nagi , Alkhuzai Khalid
Published: February 2022

This research work oriented to use Geographical Information System (GIS) in mapping and selection of dam/reservoir site in Albaha Area (KSA) based on analyzing Digital Elevation Model (DEM). The Digital Elevation Model of the study area was used as a base of this study. After identifying the most suitable site for locating dam/reservoir, three cases were studied; Higher elevation, Intermediate and Lower elevation. Results showed that the topography of the study area can be utilized to locate a proposed dam at Almikhwah province. This dam can reserve water between about 426 to 9.8 million cubic meters with a dam height of 78 to 5 m respectively. On the other hand, the proposed dam length may vary from 625 to 247m. Moreover, GIS tools with DEM reflect powerful, easy, quick, and cheap tools for preliminary dam or reservoir site selection.
Pentingnya Pembentukan Karakter Peserta Didik For The Best Future di UPTD SMPN 1 Siabu Mandailing Natal
Authors: Siregar Ardina
Published: February 2022

Peserta didik yang berkarakter akan bertindak sesuai dengan aturan dan kaidah-kaidah yang berlaku di lingkungan sekitarnya. Bangsa Indonesia saat ini sedang mengalami krisis, yaitu krisis kejujuran, tanggung jawab, tidak berpikir jauh ke depan, disiplin, kebersamaan, keadilan, dan kepedulian. tujuan dari Pengabdian Kepada Masyarakat yang dilaksanakan oleh kelompok kami ini adalah untuk meningkatkan potensi peserta didik agar menjadi manusia yang beriman dan bertakwa kepada Tuhan Yang Maha Esa, berakhlak mulia, sehat, cakap, kreatif, mandiri, dan menjadi warga negara yang demokratis serta bertanggung jawab, agar terciptanya pendidikan yang berkarakter. Metode dalam kegiatan ini dilakukan secara bertahap yaitu dengan melihat masalah yang muncul kemudian menyelesaikan gejala yang muncul tersebut
INORGANIC WASTE RECYCLING
Authors: Jayadi Yusma Indah
Published: February 2022

Indonesia merupakan penghasil sampah plastik terbesar nomor 2 di dunia. Banyaknya sampah di indonesia dipengaruhi oleh jumlah penduduk, pertumbuhan ekonomi dan perubahan pola konsumsi masyarakat. Program pengabdian masyarakat dilaksanakan untuk menanamkan kepedulian terhadap masyarakat dan pengetahuan akan manfaat dari sampah. Tujuan program ini dilaksanakan untuk memberi edukasi  terkait sampah dan kebersihan lingkungan melalui sosialisasi daur ulang sampah anorganik pada SD Inpres Bertingkat. Metode edukasi adalah ceramah dengan visual dan simulasi daur ulang sampah anorganik, dilakukan pre dan post test dan rekomendasi kepada kepala sekolah.  Hasil menunjukkan terdapat perbedaan yang signifikan p=0,000 sebelum dan setelah edukasi. Pengetahuan kategori baik pada siswa  meningkat 41,1%. Pihak sekolah diharapkan dapat melanjutkan edukasi pemisahan sampah anorganik dan organik, untuk menciptakan lingkungan yang bersih dan sehat, selain itu melakukan pengolahan sampah anorganik di lingkungan sekolah dan mengikut sertakan dalam mata pelajaran prakarya atau seni budaya.
SOSIALISASI SISTEM INFORMASI PERSEDIAAN BARANG PADA PT. IMMUNOTEC PROFARMASIA
Authors: Wilda Rina Hasibuan Wilda
Published: February 2022

Pengelolaan data dengan menggunakan teknologi komputer yang semakin maju seiring dengan perkembangan hardware dan software   sudah pasti akan mempermudah dalam pengolahan data penjualan dan pembelian serta persediaan barang. Sistem Persediaan barang pada PT. Immunotec Profarmasia Impro Best PRO masih manual dan belum terintegrasi dengan baik. Penanganan dengan sistem manual sering terjadi kendala seperti terjadinya kesalahan dalam pengecekan stok barang sehingga laporan menjadi  redudansi data yang mengakibatkan  proses pencarian data stok barang membutuhkan waktu yang lama. Dibangunnya sistem informasi ini diharapkan dapat membantu PT. Immunotec Profarmasia Impro Besr PRO dalam mengelola data persediaan barang yang diperoleh dari pembelian dan penjualan. Dalam pembuatan sistem informasi persediaan menggunakan bahasa pemrograman visual Basic 2008 dan SQL Server sebagai databasenya. Aplikasi sistem informasi persediaan barang diharapkan dapat memonitoring stok barang yang masuk maupung barang yang keluar agar mampu meningkatkan efektifitas dan efisiensi perusahaan.Penerapan sistem informasi nantinya dapat memaksimalkan kinerja para pegawai sehingga mendapatkan hasil yang lebih baik dan pemrosesan data menjadi lebih  cepat.
Asymmetric Biomechanical Properties of the Paravertebral Muscle in Elderly Patients With Unilateral Chronic Low Back Pain: A Preliminary Study
Authors: Wu Zugui , Ye Xiangling , Ye Zixuan , Hong Kunhao , Chen Zehua , Wang Yi , Li Congcong , Li Junyi , Huang Jinyou , Zhu Yue , Lu Yanyan , Liu Wengang , Xu Xuemeng
Published: February 2022

Background: Clinical incidences of chronic low back pain among the elderly are increasing. However, studies have not fully elucidated on changes in biomechanical properties of paravertebral muscles in patients with unilateral chronic low back pain. We evaluated the changes in biomechanical properties of painful and non-painful paravertebral muscles in elderly patients with unilateral chronic low back pain.

Methods: Biomechanical properties of paravertebral muscles, including muscle tone and stiffness, in elderly patients with unilateral chronic low back pain were measured using MyotonPRO. Lumbar Lordosis and Sacral Slope were measured by magnetic resonance imaging. Cross-sectional areas of paravertebral muscles were evaluated using ImageJ software version 1.53. Chronic low back pain severity was assessed by Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI) scores. The correlations between VAS scores, ODI scores, Lumbar Lordosis, Sacral Slope, cross-sectional areas (painful side), disease duration, and biomechanical properties of paravertebral muscles in the painful side were analyzed.

Results: A total of 60 elderly patients with unilateral chronic low back pain were enrolled in this study. The muscle tone and stiffness of paravertebral muscles on the painful side were significantly higher than those on the non-painful side (p < .05). Cross-sectional areas of paravertebral muscles on the painful side at the L3 level were smaller than those of the non-painful side (p < .05). The VAS scores and ODI scores were significantly positively correlated with muscle tone and stiffness of paravertebral muscles on the painful side (p < .05 and p < .01, respectively). There were no significant correlations between disease duration, cross-sectional areas (painful side), Lumbar Lordosis, or Sacral Slope and muscle tone and stiffness of paravertebral muscles on the painful side (p > .05).

Conclusion: In elderly patients with unilateral chronic low back pain, muscle tone and stiffness of paravertebral muscles on the painful side are higher than for those on the non-painful side. The asymmetry of biomechanical properties of paravertebral muscles is associated with severity of chronic low back pain.
Isolation and Investigation of Natural Rare Earth Metal Chelating Agents From Calothrix brevissima - A Step Towards Unraveling the Mechanisms of Metal Biosorption
Authors: Jurkowski Wojciech , Paper Michael , Brück Thomas B.
Published: February 2022

In this study water soluble compounds that form complexes with Rare Earth Elements (REE) and other metals were isolated fromCalothrix brevissimabiomass with chromatographic methods for the first time. Molecular characterization showed that the isolated compounds are most likely polysaccharides comprised of arabinose, xylose, mannose, galactose and glucose. FT-IR analysis revealed functional groups involved in the binding mechanism of Tb are likely sulfate- and to a lesser extend hydroxyl-groups. The binding specificity of the isolated compounds was investigated with different metal solutions. Here, ions of the alkali and alkaline earth metals Na, K, Mg and Ca showed no competition for Tb-binding even at 10-fold excess concentration. Ions of the elements Co and Pb on the other hand replaced Tb at higher concentrations. Addition of the isolated compounds significantly reduced the precipitation of Eu at pH-values between 6.7 and 9.5, indicating that the interaction between the isolated chelators and Rare Earth Metals is stable even at high pH-values.
A Glimpse of Programmed Cell Death Among Bacteria, Animals, and Plants
Authors: Zhuang Jun , Xie Li , Zheng Luping
Published: February 2022

Programmed cell death (PCD) in animals mainly refers to lytic and non-lytic forms. Disruption and integrity of the plasma membrane are considered as hallmarks of lytic and apoptotic cell death, respectively. These lytic cell death programs can prevent the hosts from microbial pathogens. The key to our understanding of these cases is pattern recognition receptors, such as TLRs in animals and LRR-RLKs in plants, and nod-like receptors (NLRs). Herein, we emphatically discuss the biochemical and structural studies that have clarified the anti-apoptotic and pro-apoptotic functions of Bcl-2 family proteins during intrinsic apoptosis and how caspase-8 among apoptosis, necroptosis, and pyroptosis sets the switchable threshold and integrates innate immune signaling, and that have compared the similarity and distinctness of the apoptosome, necroptosome, and inflammasome. We recapitulate that the necroptotic MLKL pore, pyroptotic gasdermin pore, HR-inducing resistosome, and mitochondrial Bcl-2 family all can form ion channels, which all directly boost membrane disruption. Comparing the conservation and unique aspects of PCD including ferrroptosis among bacteria, animals, and plants, the commonly shared immune domains including TIR-like, gasdermin-like, caspase-like, and MLKL/CC-like domains act as arsenal modules to restructure the diverse architecture to commit PCD suicide upon stresses/stimuli for host community.
Nerve Dependence in Colorectal Cancer
Authors: Zhang Lincheng , Yang Ludi , Jiang Shuheng , Yu Minhao
Published: February 2022

Cancerous invasion of nerves has been reported in a list of malignant tumors as a high-risk pathological feature and marker of poor disease outcome especially in neurotrophic cancers (such as in pancreas and prostate), indicating that although once neglected, nerves could have played a pivotal role in tumorigenesis and cancer progression. In colorectal cancer, perineural invasion, a specific form of tumor-nerve interaction referring to the identification of tumor cells in proximity to the nerve, has been recognized as a strong and independent prognosis predictor; denervation of autonomic nerves and enteric nerves have shown that the existence of these nerves in the gut are accompanied by promoted cancer proliferation, further supporting that nerve is a potential accomplice to shield and nurture tumor cells. However, the precise role of nerve in CRC and the pattern of interaction between CRC cells and nerve has not been unveiled yet. Here we aim to review some basic knowledge of the importance of nerves in CRC and attempt to depict a mechanistic view of tumor-nerve interaction during CRC development.
Simultaneous Determination of RDX and HMX in Rat Plasma by LC-MS/MS and its Applications
Authors: Zhang Xi , An Zhuoling , Lv Yali , Li Guangrun , Liu Lihong , Li Pengfei
Published: February 2022

Background: 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) can cause serious toxicity problems in humans and animals, but direct analyses of RDX and HMX in biological samples are very limited. A rapid and efficient liquid chromatography-electrospray quadrupole linear ion trap mass spectrometry (LC-MS/MS) method suitable for the simultaneous determination of RDX and HMX in rat plasma after intravenous administration of two nitramine compound mixed solutions has been developed.

Methods: Plasma samples were pretreated with one-step protein precipitation, the plasma consumption is as low as 100 μl. RDX, HMX, and internal standard mycophenolic acid were eluted for 8.0 min on a reversed-phase C18 analytical column with a water/acetonitrile mixture as the mobile phase. An electrospray ionization (ESI) source was applied and operated in negative ion mode. The optimized mass transition ion pairs (m/z) monitored for RDX, HMX, and internal standard mycophenolic acid were m/z 284.1→61.7, m/z 331.0→108.8, and m/z 319.2→191.1, respectively.

Results: The detection ranges of both RDX and HMX in plasma were 5.00–200.00 ng⋅ml−1 with an LOD of 1.00 ng⋅ml−1. The extraction recoveries of RDX and HMX were 60.04 ± 4.18% and 79.57 ± 3.35%, respectively. The precision and accuracy met the requirements, and the method was stable under all tested conditions.

Conclusion: The present method is miniaturized, effective, portable, rapid and can be easily used for simultaneous quantification of RDX and HMX in rat plasma.
PSMA-Targeted Supramolecular Nanoparticles Prepared From Cucurbit[8]uril-Based Ternary Host–Guest Recognition for Prostate Cancer Therapy
Authors: Zhang Xueyan , Qi Shaolong , Liu Dahai , Du Jianshi , Jin Jingji
Published: February 2022

Nanomedicines play an important role in cancer therapy; however, some drawbacks including unsatisfactory efficacy and side effects arising from indiscriminate drug release retard their clinical applications. Although functionalization of nanomedicines through covalent interactions can improve the pharmacokinetics and efficacy of the loaded drugs, complicated and tedious synthesis greatly limits the exploration of multifunctional nanoparticles. Herein, we utilize a supramolecular strategy to design a nanomedicine for targeted drug delivery through cucurbit[8]uril-based host–guest ternary complexation and successfully prepare prostate-specific membrane antigen (PSMA)-targeted supramolecular nanoparticles encapsulating doxorubicin (DOX). In vitro studies exhibit targeted modification via noncovalent enhance anticancer efficiency of DOX due to the increased cell uptake on account of receptor-mediated endocytosis. This design provides a new strategy for the development of sophisticated drug delivery systems and holds perspective potentials in precise cancer treatments.