bluuebunny/crossref_metadata_2025 huggingface dataset:
Privacy-Preserving Deep Learning for the Detection of Protected Health Information in Real-World Data: Comparative Evaluation (Preprint)
Authors: Festag Sven , Spreckelsen Cord
Published: March 2019

BACKGROUND

Collaborative privacy-preserving training methods allow for the integration of locally stored private data sets into machine learning approaches while ensuring confidentiality and nondisclosure.

OBJECTIVE

In this work we assess the performance of a state-of-the-art neural network approach for the detection of protected health information in texts trained in a collaborative privacy-preserving way.

METHODS

The training adopts distributed selective stochastic gradient descent (ie, it works by exchanging local learning results achieved on private data sets). Five networks were trained on separated real-world clinical data sets by using the privacy-protecting protocol. In total, the data sets contain 1304 real longitudinal patient records for 296 patients.

RESULTS

These networks reached a mean F1 value of 0.955. The gold standard centralized training that is based on the union of all sets and does not take data security into consideration reaches a final value of 0.962.

CONCLUSIONS

Using real-world clinical data, our study shows that detection of protected health information can be secured by collaborative privacy-preserving training. In general, the approach shows the feasibility of deep learning on distributed and confidential clinical data while ensuring data protection.
A relação da escolarização e os efeitos para a escolha do projeto de vida de estudantes surdos
Authors: Gonçalves Arlete Marinho
Published: March 2019

O estudo tem como objetivo apreender a relação da escolarização e os efeitos para a escolha do projeto de vida de estudantes Surdos. A fundamentação teórica está embasada na Teoria das Representações Sociais (RS) de abordagem dimensional. Tem-se como metodologia a abordagem descritiva - analítica com a utilização da técnica de associação livre de palavras. Os dados foram analisados a partir da associação entre fatores que se relacionam para se chegar as RS. Os resultados apontam que os projetos de vida dos estudantes Surdos se estruturam a partir da construção histórica de suas vivências no âmbito escolar, principalmente às relacionadas na educação básica. Esse processo ajudou os alunos Surdos a ter conhecimento, enfrentar desafios, se desenvolver e descobrir seus interesses. As correlações que assinalam a escolarização foram apontadas por representações de situações de exclusão, a descoberta da Língua de Sinais como opção para o seu desenvolvimento escolar e a escolha da faculdade.
mulheres na filosofia de Montesquieu
Authors: Carvalho Reis Patrícia
Published: March 2019

Este artigo trata da questão das mulheres na filosofia de Montesquieu, especialmente, em duas de suas obras: “Cartas Persas” e “Do Espírito das Leis”. No romance “Cartas Persas”, alguns personagens de Montesquieu relatam a forma pela qual as mulheres vivem no serralho de Usbek assim como em outros lugares do mundo, como na Itália e na França. Além disso, nesse romance, há uma comparação entre a posição da mulher e a do homem na sociedade, e um questionamento sobre a legitimidade de tais posições. Na obra “Do Espírito das Leis”, Montesquieu trata do comportamento das mulheres nos diferentes tipos de regime.
Hubungan Motivasi Berprestasi, Prilaku Kepemimpinan Kepala Sekolah dan Etos Kerja dengan Kinerja Guru
Authors: Putra Cok Agus Ady , Yudana Made , Natajaya Nyoman
Published: March 2019

This study aimed to determine: (1) the relationship between achievement motivation with teacher performance, (2) the relationship between principal leadership behaviors with teacher performance, (3) the relationship between the performance of the teachers  work ethic, (4) simultaneous relationship between achievement motivation, school leadership and work ethic with the performance of. This study was designed with a correlational design ex-post facto by using a quantitative approach.The study population was  all teachers in SMA N 1 Kubutambahan. The sample retrieval technique using census study with the number 47. Data were collected by questionnaires. Data were analyzed by multiple regression and partial analysis. The results showed that: (1) there is a significant contribution to the achievement motivation with teacher, (2) there is a significant contribution between principal leadership behaviors with teacher performance, (3) there is a significant contribution to the work ethos of teacher performance, (4) there is a significant contribution between achievement motivation, school leadership behavior, and work ethos simultaneously with the performance of teachers
Determinasi Sikap Guru terhadap Profesinya, Konsep Diri, dan Iklim Kerja Sekolah terhadap Kinerja Guru Sekolah Dasar
Authors: Sugiarta Made Pasek , Dantes Nyoman , Natajaya Nyoman
Published: March 2019

This study aims to determine the attitude of teachers towards professional  determination, self-concept, and the climate of primary school to the performance. This study is “ex-post facto” population of 83people, 73 people sample. Data collection tool is in the form of questionnaires, data analysis with regression techniques. The  result showed that: (1) there is a significant determinant between teacher attitudes the profession with teacher performance with the correlation coefficient of 0.401, (2) there is a significant determinant between self-concept of teachers with teacher performance with the correlation coefficient of 0.325, (3) there is a determination significant difference between the climate of the school with teacher performance with correlation coefficient of 0.337, contributing 11.3% and the effective contribution of 6.2%, (4) the co-operation between teachers’ attitudes towards the profession, self-concept, and work climate with performance teachers with multiple correlation coefficient of 0.465 and a 21.6% contribution to the performance of teachers.
Hubungan Kepemimpinan Situasional, Motivasi Kerja, dan Iklim Kerja dengan Kinerja Guru
Authors: Suandi I Wayan , Lasmawan Wayan , Natajaya Nyoman
Published: March 2019

This research aimed to investigate: 1) the relationship between situational leadership and teachers’ performance, 2) the relationship between working motivation and teachers’ performance, 3) the relationship between working climate and teachers’ performance, 4) The relationship among situational leadership, working motivation, and working climate on the performance of teachers of public junior high school. The population is 98. This research used census study with the design of expost-facto. The data were collected using the questionnaire. The data were analyzed using multiple regressions. The results of the research show that there is a positive and significant relationship between: 1) situational leadership and teachers’ performance with the contribution of 39,5%, 2) working motivation and teachers’ performance with the contribution of 69.1%, 3) working climate and teachers’ performance with the contribution of 55.0%, 4) situational leadership, working motivation, and working climate on the performance of teachers of public junior high school in Negara Subdistric with the coantribution of 77.1%.
Metode Tongkat Berbicara (Talking Stick) dalam Pembelajaran Keterampilan Berbicara Menanggapi Cerita Pendek
Authors: Sibuea Mawar Sri Wulan Br. , Syahfitri Dian
Published: March 2019

This study aims to describe the improvement of speech skills in responding to students' short stories through the application of the stick talking method. This study is based on learning to speak in response to the short story on the students in the category of low. The method used in this study is qualitative descriptive with a classroom action approach that describes speaking skills to respond to classical short stories and speaking skills in response to a short story through a talking stick method. in practive both two cycles consisting of the planning stage, the execution of the action, the observation, and the reflection. The subject of this study were samples dran bypurposive sampling technique of 30 students of class VII-C SMP Negeri 40 Medan. The results showed that students 'ability to respond to the students' short story increased after talking stick method was applied in the pre-cycles, the average score was 52.33 and the percentage of classical completeness was 20% After applying the method of talking stick ), the result of the students 'test scores on the first cycle obtained an average score of 69.5 and increased to 71.67 in the second cycle test.Based on the percentage of students' classical completeness in cycle I 66.67% increase in cycle II 76.67%. The research concluded that the application of talking stick method can improve the speaking skill in responding to the short story in the students of class VII-C SMP Negeri 40 Medan.
Analisis Semiotik “Hujan Bulan Juni” vs ”Percakapan Senja”
Authors: Sifa Sifa
Published: March 2019

Penelitian ini bertujuan untuk membandingkan secara semiotik antara puisi “Hujan Bulan Juni” Sapardi Joko Damono dengan “Percakapan Senja” Gde Artawan. Secara semiotis fisis, lirik puisi Gde Artawan memiliki unsur kesepadanan dalam pilihan kata, membenamkan kata sarat makna sebagaimana halnya puisi Sapardi Joko Damono. Meski puisi ini lahir dalam waktu yang tidak bersamaan, namun ada nuansa batin yang bisa disandingkan. Metode yang diterapkan dalam penelitian ini adalah analisis deskriptif dengan semiotik sebagai pisau analisis. Ada pergumulan batin yang mendalam dalam “Hujan Bulan Juni” versus “Percakapan Senja”. Pada “Hujan Bulan Juni” diakhiri dengan “happy ending” sedang dalam “Percakapan Senja” berakhir dengan sad ending“puisi “Hujan Bulan Juni” berujung manisnya sebuah penantian panjang. Ia mendapatkan seseorang yang sangat dinantinya, dengan penuh tulus kasih. Ia membiarkan tak terucapkan segala apa yang ia rasa selama menanti. Sedangkan puisi “Percakapan Senja” menggambarkan tentang akhir sebuah kebersamaan yang menuai titik kebuntuan yang dilatarbelakangi oleh perbedaan yang sangat kuat dan ketiadaan kemauan yang kuat pula untuk saling melebarkan diri menjadi sebuah ikatan yang kuat. Pada akhirnya saling membiarkan masing-masing berjalan sesuai dengan jalurnya.
Memahami Arti Laba melalui “Semak”
Authors: Martadinata Sudrajat , Suprapto Deddy
Published: March 2019

Memahami Arti Laba Melalui “Semak” dipilih sebagai judul karena; Pertama, kata “semak” adalah akronim dari Semiotika Akuntansi. Kita akan melihat bagaimana wajah akuntansi (arti laba) jika ditinjau dari sudut pandang semiotika. Kedua, “semak” memiliki makna literal yang berhubungan dengan objek penelitian ini yaitu Perusahaan Kehutanan sehingga akronim dan objek penelitian memiliki relasi makna. Objek penelitian adalah PT Bumi Teknokultura Unggul Tbk yang telah terdaftar di Bursa Efek Indonesia (BEI). Tujuan penelitian ini untuk memahami arti laba yang disajikan dalam laporan tahunan mereka. Pengumpulan data dengan teknik dokumentasi, Dokumentasi dilakukan dengan mengunduh annual report PT Bumi Teknokultura Unggul Tbk. Fokusnya menganalisis narrative text tentang keseluruhan kondisi perusahaan pada akhir periode akuntansi. Narrative text dianalisa dengan pendekatan semiotika. Hasil penelitian ini menemukan arti laba adalah kesungguhan, prestasi, dan eksistensi diri sebuah perusahaan. Melalui semiotika akuntansi dengan makna kesungguhan, prestasi, dan eksistensi diri sebuah perusahaan diharapkan dapat memperkuat komunikasi bisnis secara intensif.
The effect of different proportions of Medicago media Pers. in mixtures with Festulolium braunii (K. Richt.) A. Camus on the yield and feed value of green fodder
Authors: Olszewska Marzenna , Grzegorczyk Stefan , Bałuch-Małecka Anna
Published: March 2019

A field experiment was performed in 2011–2013. The aim of the study was to determine the effect of different proportions of Medicago media in mixtures with Festulolium braunii on the yield and feed value of green fodder, including the content of crude protein (CP) and water-soluble carbohydrates (WSC), and the carbohydrate-to-protein ratio. It was found that alfalfa had a high competitive advantage over Festulolium. In the second and third year of full utilization, alfalfa was the predominant species in the tested mixtures regardless of the proportion of sown seeds. The mixtures with alfalfa were characterized by high and stable dry matter yields and high protein content, whereas Festulolium significantly increased the content of WSC and improved the WSC:CP ratio. The evaluated mixtures had a higher feed value than pure-sown components. The results of the study indicate that Festulolium mixtures with a lower proportion (30% and 50%) of alfalfa are characterized by a higher feed value.
Evaluation of the ejaculate microbiota by real-time PCR and culture-based technique
Authors: Voroshilina ES , Zornikov DL , Panacheva EA
Published: March 2019

Among other things male sterility can be caused by inflammatory diseases of the urogenital tract, often associated with opportunistic microorganisms. Thus, it is necessary to implement modern methods for the detection and identification of opportunistic microorganisms in the urogenital tract. The aim of the work was to conduct comparative analysis of the ejaculate microbiota from men of the reproductive age and studied using quantitative polymerase chain reaction (PCR) and culture method. 86 samples of ejaculate collected from men aged 18–57 years after observing sexual abstinence for 3–5 days were examined. With culture study in 50% of samples we observed growth of gram positive facultative anaerobic bacteria in the amount less than 103 CFU/ml; in 16.3% of samples — the growth of bacteria was not observed. With real-time PCR in each sample 8–15 groups of microorganisms were detected (including the prevailing groups) in the amount of 102–106 GE/ml. In all 86 samples obligate anaerobes that cannot not be cultured in vitro were detected. The predominant groups of microorganisms, as determined by real-time PCR, were detected by the culture method only in 24.4% of cases.
Acciones técnico-tácticas, factores contextuales y rendimiento deportivo de los equipos de concacaf durante la clasificación a rusia 2018
Authors: Ugalde-Ramírez JA , Rivas-Borbón OM , Rojas-Valverde D
Published: March 2019

El objetivo de este estudio fue determinar cuáles acciones técnico-tácticas y factores contextuales se relacionaron con el rendimiento deportivo de las selecciones absolutas de CONCACAF durante la fase clasificatoria a la Copa Mundial de Rusia 2018. Se utilizaron las estadísticas de los 10 partidos jugados por cada una de los 6 equipos nacionales (30 partidos, 60 observaciones). Los resultados indican que las acciones técnico-tácticas que se relacionaron con el rendimiento y que diferenciaron a los equipos clasificados y no clasificados, así como a los equipos que obtenían victorias con los que empataban o perdían, fueron: los goles, remates a marco realizados, pases, y posesión de balón, asimismo estos equipos consiguieron mayor cantidad de victorias cuando jugaban de locales. En conclusión, las acciones técnico-tácticas relacionadas con el rendimiento coinciden con las reportadas en la literatura, además, el hecho de jugar de local representó una ventaja para los equipos.
Evaluación de los centros laterales en contra y saques de banda a favor en fútbol semiprofesional. Estudio de caso.
Authors: García-Paúl Álvaro Jesús , Valera-Sánchez Eduardo , Castillo-Rodríguez Alfonso
Published: March 2019

El scouting deportivo, match analysis, o análisis del juego en deportes de interacción ha cobrado especial interés desde la última década. La preocupación y la importancia en el fútbol por la victoria hacen que se sume la forma de juego y las fortalezas que posee el equipo que te vas a enfrentar. Para ello, esta nueva metodología de análisis, evaluación y valoración de acciones del juego permiten obtener información muy pertinente por parte de los entrenadores. El objetivo de este estudio fue analizar a través de la metodología observacional, las acciones erróneas y correctas que se llevan a cabo en un equipo semiprofesional de fútbol en partidos reales, concretamente en los centros laterales en contra y los saques de banda a favor en fútbol. Veintitres jugadores semiprofesionales del Sur de España, fueron los participantes del estudio. Se crearon instrumentos ad-hoc para el acotamiento de las acciones a evaluar, siendo el número total en cada uno de los problemas a analizar de 50. Los resultados mostraron detalles de las categorías y elementos que determina un problema real en el equipo analizado, permitiendo un margen de mejora con los aspectos reseñados como positivos. Como conclusión, los principales hallazgos de este estudio mostraron que el equipo analizado de fútbol semiprofesional posee problemas en el juego como son en los saques de banda a favor y en los centros laterales defensivos. Esto ha sido hallado gracias a la metodología utilizada, que ha podido de manera objetiva analizar y valorar acciones que se dan en los partidos de competición, ayudando de esta manera al entrenador para realizar tareas enfocadas a paliar y mejorar el rendimiento de sus jugadores, optimizando el aspecto táctico del equipo, objetivo fundamental de la metodología activa.
Los juegos reducidos como metodología de enseñanza en el fútbol.
Authors: Abad Robles Manuel Tomás , Fernández-Espínola Carlos , Giménez Fuentes-Guerra Francisco Javier
Published: March 2019

El objetivo de este trabajo fue analizar los juegos reducidos como metodología de enseñanza en el fútbol. Para ello, se realizó un análisis de revisiones sistemáticas que versan sobre esta temática. La búsqueda se realizó en las bases de datos de Web of Science Scopus y Google Scholar, seleccionando un total de cuatro estudios. Los resultados de estas revisiones mostraron que la planificación y organización del entrenamiento con juegos reducidos determinan el éxito de los objetivos físicos o táctico-técnicos que pretendemos conseguir. Para ello, en la preparación de entrenamientos con juegos reducidos es importante que los entrenadores/docentes de Educación Física tengan en cuenta variables como el número de jugadores, el tamaño del espacio de juego, la modificación de reglas, la estimulación del entrenador, la presencia o no de porteros, o el tiempo de trabajo y de descanso. Basándonos en las evidencias científicas analizadas en este trabajo, podemos corroborar que los juegos reducidos permiten llevar a cabo un entrenamiento óptimo y simultáneo en cuanto al trabajo de las habilidades táctico-técnicas y de condición física.
Small intestinal diverticula
Authors: Parfenov A I , Krums L M , Pavlov M V
Published: March 2019

The prevalence of small intestinal diverticula (SID) in the population is 0.5-2.3%, and in most cases they are asymptomatic. In the presence of small intestinal bacterial overgrowth this results in chronic diarrhea and malabsorption. When it is complicated by diverticulitis it causes pain and other symptoms of inflammatory bowel disease. Inflammatory process progression may be accompanied by bleeding, invagination, intestinal obstruction, diverticulum abscess and perforation with peritonitis development. SID include separate nosological forms such as paraphateral diverticulum and Meckel's diverticulum. In diagnosis of SID ray and endoscopic methods are crucial. The basis of small intestine diverticular disease treatment is intestinal antiseptics, antibiotics as well as surgical intervention for severe complications. Two cases are discussed, the first one confirms a possibility of development of severe malabsorption syndrome with chronic diarrhea, and the second one is a complication in a form of severe diverticulitis, abscess with perforation and peritonitis.
Comparison of the integral indices of the vectorcardiogram with the data of echocardiography in patients with idiopathic and chronic thromboembolic pulmonary hypertension
Authors: Sakhnova T A , Blinova E V , Belevskaya A A , Saidova M A , Arkhipova O A , Yurasova E S , Alokova F H , Martynyuk T V , Chazova I Ye
Published: March 2019

The aim of the work is to compare vectorcardiographic (VCG) variables - spatial QRS-T angle and electrocardiographic ventricular gradient (VG) with echocardiography (EchoCG) data in patients with idiopathic pulmonary hypertension (IPH) and chronic thromboembolic pulmonary hypertension (CTEPH). Materials and methods. In 40 patients with IPH and 40 patients with CTEPH at the age of 45±12 years, systolic pulmonary artery pressure (SPAP); the sizes of heart chambers, parameters of RV systolic and diastolic function were evaluated with EchoCG. The QRS-T and VG angles were calculated on the VCG, derived from 12-lead digital ECG. Results. In all patients SPAP was greater than 40 mm Hg (mean 83±18 mm Hg), EchoCG data indicated hypertrophy and dilatation of RV, its systolic and diastolic function; dilatation of the right atrium (RA). Prognostically unfavorable changes in EchoCG were observed: the presence of pericardial effusion in 35 (44%) patients, RA area greater than 26 cm2 in 18 (23%) patients; TAPSE less than 1.5 cm in 37 (46%) patients. EchoCG and VCG variables had statistically significant differences in patients with III-IV functional class in comparison with I-II functional class. Statistically significant moderate correlations between VCG and EchoCG variables were revealed. VCG variables allowed to separate patient groups with the presence and absence of prognostically unfavorable changes in EchoCG with sensitivity from 54 to 78% and specificity from 66 to 87%. Conclusion. In patients with IPH and CTEPH, changes of QRS-T angle and VG correlate with SPAP, the size of RV and RA, parameters of RV systolic and diastolic function. The possibility of the use of QRS-T angle and VG for the detection of patients with prognostically unfavorable echocardiographic changes in the general group of patients with IPH and CTEPH has been shown.
Difficulties in Goodpasture's syndrome diagnosing
Authors: Podzolkov V I , Makhnach G K , Ishina T I , Ponomarev A B , Medvedev I D
Published: March 2019

The article analyzes the diagnosis and treatment of anti-GBM antibody disease (Goodpasture's syndrome) - a rare, severe progressive disease, associated with anti-glomerular basement membrane antibody-induced pulmonary hemorrhage and glomerulonephritis. The main problem of this pathology is late diagnosis, resulted in ineffective treatment. The article provides current information on the epidemiology, etiology and pathogenesis, diagnosis, and treatment of Goodpasture’s syndrome, as well as clinical case of a patient with this rare disease.
Association of SOCS5 gene polymorphism with allergic bronchial asthma
Authors: Averyanov A B , Chercashina I I , Nikulina S Yu , Maksimov V N , Shestovitskiy V A
Published: March 2019

Aim: to study the association of mononucleotide polymorphism rs6737848 SOCS5 gene with the risk of development of allergic bronchial asthma. Material and methods. Totally 59 patients studied (19 males, 40 females) with allergic bronchial asthma and 50 healthy people (29 males, 21 females) of controls. All patients underwent clinical and instrumental and laboratory investigations in KICH №20 (Krasnoyarsk city) and molecular-genetic investigation of DNA in the Russia-Italian laboratory “MAGI” (Krasnoyarsk city) and Institution of Internal and Preventive Medicine (Novosibirsk city). Statistics included standard programs: Statistica for Windows 7.0. Results. The results of the study showed statistical predominance of prevalent genotype СС of SOCS5 gene in allergic bronchial asthma patients, comparing to control group. Conclusion. Homozygous genotype of СС gene of SOCS5 is a risk factor for allergic bronchial asthma.
Combined oral contraceptives with natural estrogen and sexual function: the optimal method of contraception for women of different ages
Authors: Yureneva Svetlana V , Ilina Liliia M
Published: March 2019

Background. Combined oral contraceptives (COCs) are the most common method of prevention of unwanted pregnancies in women from the early reproductive period to perimenopause, therefore their impact on quality of life, sexual function and general well-being remains the subject of active discussion. Some studies revealed various manifestations of sexual dysfunction in patients receiving COCs, therefore such questions, as well as the advantages / disadvantages of individual components (their type and dose) of drugs, are of interest to the clinician. Aim. Assess mechanisms of influence of COCs on female sexual function. Materials and methods. In order to write this review domestic and foreign publications were searched in Russian and international search systems (PubMed, elibrary, etc.) for the last 2-15 years. Relevant articles from the peer-reviewed literature were included. Results. Many studies proved a beneficial effect of estradiol valerate (E2V) which is estrogen identical to natural one in a combination with dienogest (DNG) which is 4th generation progestin in a dynamic dosing regimen on quality of life and sexual function. This beneficial effect is achieved due to combined effects of both components of the drug as well as its reception mode. Conclusion. The combination of estradiol valerate (E2V) which is estrogen identical to natural one with dienogest (DNG) which is 4th generation progestin may be the optimal method of contraception for women of any age, including the young, with decreased libido while taking other COCs.
The results of assisted reproductive technology programs in patients with “thin” endometrium
Authors: Nigora F Abdurakhmanova , Anna D Gvozdeva , Marina M Ziganshina , Nataliya V Dolgushina
Published: March 2019

Relevance. Effectiveness of assisted reproductive technology (ART) programs is quite high, but for couples who have already had failed attempts of ART programs the likelihood of getting pregnant decreases with each subsequent attempt. Low endometrial thickness is a common cause of a decline in a possibility of getting pregnant. However, data on predictive value of this index in ART programs are contradictory. Some researchers do not find a correlation between the endometrium thickness and ART programs outcomes. Other researchers revealed a statistically significant relationship between endometrium thickness and pregnancy rate in ART cycles. Aim. To evaluate an effect of “thin” endometrium on pregnancy rate in ART programs. Materials and methods. 154 couples who applied for infertility treatment in ART programs were included in this prospective study. The patients were stratified into groups depending on whether a pregnancy to occur: Group 1 (n=43) - pregnancy occurred and Group 2 (n=111) - pregnancy did not occur. Then the endometrial thickness threshold determining pregnancy occurrence was identified by ultrasound and two additional groups were formed: Group 3 (n=85) - patients with “thin” endometrium, Group 4 (n=69) - patients with normal endometrial thickness. Results. The endometrial thickness threshold at which pregnancy probability, as well as the model and area under the curve (AUC) reliability were maximum, was 8.0 mm (AUC=86.7%, sensitivity - 97.7%, specificity - 75.7%). The adjusted odds ratio of pregnancy occurrence depending on endometrial thickness given the excellent quality blastocysts obtained, was 9.1 (95% confidence interval 4.3-19.3). Factors affecting endometrial thickness were endometrial polyps with polypectomy and spontaneous miscarriages in anamnesis that was undoubtedly associated with an inflammatory genesis of endometrial damage Conclusions. "Thin" endometrium plays a negative role in ART programs reducing pregnancy likelihood by 9.1 times.
Vitamin D3 and women's health
Authors: Dobrokhotova Iuliia E , Borovkova Ekaterina I , Zalesskaya Sofya A , Skalnaya Victoria S , Borovkov Ivan M , Zaydieva Zulya S
Published: March 2019

Background. Vitamin D is an essential component that regulates calcium homeostasis and many other cellular functions. Hypovitaminosis D is associated with a risk of osteopenia, obesity, type 1 and type 2 diabetes, malignant neoplasms and immune disorders. Inadequate vitamin D intake during pregnancy increases a risk of pre-eclampsia, preterm birth, low birth weight as well as it has a negative impact on both children’s and adolescents’ health. It is important for the clinician to be known administrating of vitamin D prophylactic and therapeutic regimens according to serum 25(OH)D levels. Aim. To determine causes and effects of vitamin D deficiency and to elaborate ways of their correction. Materials and methods. To write this review a search for domestic and foreign publications in Russian and international search systems (PubMed, eLibrary, etc.) for the last 2-15 years was conducted. The review includes articles from peer-reviewed literature. Results. The article shows that vitamin D has a significant impact on both the cardiovascular, endocrine, digestive, respiratory and other systems functioning and perinatal outcomes that necessitates vitamin D deficiency correction. It provides schemes for effective therapeutic and prophylactic drug doses calculating depending on vitamin D3 blood serum concentration. Conclusion. Preference should be given to cholecalciferol (vitamin D3) due to its better absorption properties and more efficient conversion to active vitamin metabolites (class IIC).
A strategy of antimicrobial therapy of pelvic inflammatory diseases at antibiotic resistance of microbial pathogens
Authors: Pestrikova Tatiana Yu , Yurasova Elena A , Yurasov Igor V
Published: March 2019

Relevance. Antibiotic resistance of microbial pathogens is an interdisciplinary and interstate problem of major medical and socio-economic importance. If multiresistant microbial flora is detected in patients with acute or chronic forms of pelvic inflammatory diseases alternative antimicrobial combined therapy an advisability should be considered. Current trends of an increase in multiresistant gram-negative infections along with limited range of alternative treatment options dictate a need for further research. Study of alternative antibiotics effectiveness in pelvic inflammatory diseases treatment is necessary for a further development of optimal treatment regimens. Aim. To search for adequate combinations of antimicrobial therapy aimed at antibiotic-resistant pathogens. Materials and methods. To write this review a search for domestic and foreign publications in Russian and international search systems (PubMed, eLibrary, etc.) for the last 2-12 years was conducted. The review includes articles from peer-reviewed literature. Results. Fosfomycin possesses a broad spectrum of antibacterial effects including gram-positive and gram-negative aerobic bacteria. The drug is highly effective against Pseudomonas aeruginosa and Escherichia coli, anaerobic bacteria (Proteus mirabilis and Klebsiella pneumoniae) as well as against gram- positive bacteria (Staphylococcus spp., including S. aureus, S. epidermidis; Streptococcus spp., including Enterococcus faecalis). Conclusions. When multiresistant microbial flora is detected in patients with acute or chronic forms of pelvic inflammatory diseases an advisability of fosfomycin administration should be considered.
First breeding record of grasshopper sparrow in northern Durango, Mexico
Authors: Arroyo-Arroyo Samuel Ignacio , Martínez-Guerrero José Hugo , Pereda-Solís Martín Emilio , Sierra-Franco Daniel
Published: March 2019

During the breeding season the Grasshopper Sparrow (Ammodramus savannarum) is widely distributed over the plains of North America. Consisting of four subspecies its populations are classified as resident, migratory and partially migratory. In Mexico and Central America, distribution of the taxon is poorly known, especially those populations that are breeding. There is only one breeding record for the grasslands of northern Mexico in the State of Zacatecas back to the mid-1950’s. During the summer breeding season of 2017, we documented the presence of six Grasshopper Sparrows in the grassland of northern Durango. With the aid of song playback two birds actively responded to the broadcasted song. The birds performed territorial displays which facilitated our locating a nest with four nestlings. This is the first summer record for the State of Durango at Cuchillas de la Zarca, 80 km south of Parral, Chihuahua City, a Grasslands Priority Conservation Area of North America.
Differentially Private Ordinary Least Squares
Authors: Sheffet Or
Published: March 2019

Linear regression is one of the most prevalent techniques in machine learning; however, it is also common to use linear regression for its explanatory capabilities rather than label prediction. Ordinary Least Squares (OLS) is often used in statistics to establish a correlation between an attribute (e.g. gender) and a label (e.g. income) in the presence of other (potentially correlated) features. OLS assumes a particular model that randomly generates the data, and derives t-values - representing the likelihood of each real value to be the true correlation. Using t-values, OLS can release a confidence interval, which is an interval on the reals that is likely to contain the true correlation; and when this interval does not intersect the origin, we can reject the null hypothesis as it is likely that the true correlation is non-zero.Our work aims at achieving similar guarantees on data under differentially private estimators. First, we show that for well-spread data, the Gaussian Johnson-Lindenstrauss Transform (JLT) gives a very good approximation of t-values; secondly, when JLT approximates Ridge regression (linear regression with l2-regularization) we derive, under certain conditions, confidence intervals using the projected data; lastly, we derive, under different conditions, confidence intervals for the "Analyze Gauss" algorithm of Dwork et al (STOC 2014).
Concentration Bounds for High Sensitivity Functions Through Differential Privacy
Authors: Stemmer Uri , Nissim Kobbi
Published: March 2019

A new line of work demonstrates how differential privacy can be used as a mathematical tool for guaranteeing generalization in adaptive data analysis. Specifically, if a differentially private analysis is applied on a sample S of i.i.d. examples to select a low-sensitivity function f, then w.h.p. f(S) is close to its expectation, even though f is being chosen adaptively, i.e., based on the data.
Very recently, Steinke and Ullman observed that these generalization guarantees can be used for proving concentration bounds in the non-adaptive setting, where the low-sensitivity function is fixed beforehand. In particular, they obtain alternative proofs for classical concentration bounds for low-sensitivity functions, such as the Chernoff bound and McDiarmid's Inequality. In this work, we extend this connection between differential privacy and concentration bounds, and show that differential privacy can be used to prove concentration of high-sensitivity functions.
Differentially Private Confidence Intervals for Empirical Risk Minimization
Authors: Wang Yue , Kifer Daniel , Lee Jaewoo
Published: March 2019

The process of data mining with differential privacy produces results that are affected by two types of noise: sampling noise due to data collection and privacy noise that is designed to prevent the reconstruction of sensitive information. In this paper, we consider the problem of designing confidence intervals for the parameters of a variety of differentially private machine learning models. The algorithms can provide confidence intervals that satisfy differential privacy (as well as the more recently proposed concentrated differential privacy) and can be used with existing differentially private mechanisms that train models using objective perturbation and output perturbation.
COMPROMETIMENTO ORGANIZACIONAL: UM ESTUDO NACIONAL SOBRE O CONCEITO E SEU PROCESSO DE DESENVOLVIMENTO
Authors: Camargo Mário Lázaro , Júnior Edward Goulart
Published: March 2019

Os estudos sobre comprometimento organizacional tornaram-se mais frequentes no Brasil a partir de 1980. O presente artigo teve como objetivo realizar uma revisão de literatura nacional para identificar e analisar os principais tópicos de pesquisas realizadas sobre o tema, de modo que fosse possível, a partir dos resultados obtidos, pensar nas principais lacunas existentes sobre o conceito, considerando que tal procedimento serviria como ação de reconhecimento do campo, de seu desenvolvimento e, provavelmente, o ponto de partida para pesquisas posteriores. Foram encontrados 51 artigos nas bases de dados SciELO e BVS, sendo que 8 artigos eram indexados nas duas bases de dados. Desse material, foram analisados 28 artigos sendo que 4 foram excluídos por relatarem pesquisas realizadas em Portugal e 18 por não apresentarem escopo compatível. As informações analisadas foram: ano de publicação; tipo de pesquisa realizada; instrumentos utilizados; o tipo de comprometimento investigado; e variáveis consequentes e antecedentes. Ao final da análise foi possível, para além de reconhecer a importância do tema para os processos de gestão de pessoas e, portanto, para o trabalho dos profissionais da área nas organizações, identificar que o mesmo ainda se encontra carente de pesquisas para se desenvolver e se consolidar como ferramenta de diagnóstico e gestão.
Periampullary Duodenal Diverticulum with Phytobezoar and Choledocholithiasis
Authors: Abrantes João , Antunes Artur , Fernandes Clara , Granadeiro João
Published: March 2019

The patient presented with recurrent epigastric pain and recent onset jaundice, with laboratory findings showing anemia (10.5 g/dL) and increased bilirubin levels (3.40 mg/dL).
Concordance analysis of adult ankle fracture classifications
Authors: Paula Neto Antonio Candido de , Ikeuti Douglas Hideki , Santos Augusto Braga dos , Barroco Rui Dos Santos , Miranda Bruno Rodrigues de , Macedo Rafael Da Rocha
Published: March 2019

Objective: To analyze the interobserver agreement among physicians in an orthopedy and traumatology service with knowledge and training in adult ankle fracture classifications through radiographic evaluation. Methods: A cross-sectional study was carried out in which the records of 20 patients with a diagnosis of ankle fracture in 2016 (uni-, bi- or trimalleolar), aged older than 18 years or with a closed physis, were studied. The radiographs that met the criteria were analyzed and classified according to the Danis Weber (DW), Lauge-Hansen (LH) and Arbeitsgemeinschaft für Osteosynthesefragen/Orthopaedic Trauma Association (AO/OTA) classifications by two first-year residents, two second-year residents, two third-year residents and two preceptors of the service. The conditions were identical for the observers and were performed individually once. The Kappa coefficient (K) was used to assess agreement. Results: The results showed great interobserver agreement in the DW and LH classifications, with K values equal to 0.69 and 0.64, respectively. The AO/OTA classification showed moderate agreement, with K = 0.47. Conclusion: The DW classification was the most reliable among the three classifications. The AO/OTA classification showed the lowest agreement and was the least reliable, and the LH classification was in between the others. Level of Evidence III, Diagnostic Studies; Study of non consecutive patients; without consistently applied reference “gold” standard.
Multidisciplinary care of diabetic feet
Authors: Rodrigues Aldo Barbachan , Borges Vinícius Quadros , Ferreira Gabriel Ferraz , Sacilotto Roberto , Portes Evandro De Souza , Stéfani Kelly Cristina
Published: March 2019

Objective: This study evaluated the foot and ankle disorders developed among patients treated by a multidisciplinary team of the diabetic foot group outpatient clinic at our institution using a specific protocol. The natural disease progression of these patients was examined after a 12-year follow-up period. Methods: The data collected included gender, age, body mass index, disease duration, insulin use, duration of insulin use, tobacco use, peripheral pulse palpation, history of previous partial foot amputations, foot deformities secondary to peripheral neuropathy, degree of foot sensation assessed using the Semmes-Weinstein monofilament test, association with ulcers as evaluated by the Wagner classification, and the presence of Charcot foot as evaluated by the Brodsky anatomical classification and the Eichenholtz radiographic classification. Results: We prospectively evaluated 578 patients with type 2 diabetes and found that they had a mean disease progression of 14 years; 53% were insulin-dependent, with an average insulin use duration of 9.7 years; 9.8% of patients had previous amputations performed by a vascular surgeon due to acute arterial insufficiency; 72.6% lost protective sensation according to the sensation assessment associated with deformities secondary to peripheral neuropathy; and 21.5% presented with hallux valgus and claw toes, 12.6% presented with ulcers, and 9.5% presented with Charcot neuroarthropathy. Conclusion: A treatment protocol overseen by a multidisciplinary team and the use of therapeutic footwear to protect insensitive feet were associated with low rates of plantar foot ulcers and Charcot neuroarthropathy. Level of Evidence II; Therapeutic Studies; Comparative Prospective.
Analisis Frekuensi Kata untuk Mengekstrak Kata Kunci dari Artikel Ilmiah Berbahasa Indonesia
Authors: Sri Arini Ni Wayan , Putu Widja Ida Bagus , Yasa Negara I Komang Rinartha
Published: March 2019

Publikasi hasil penelitian merupakan suatu proses yang harus dilaksanakan dalam sebuah kegiatan penelitian. Publikasi dapat dilaksanakan dalam bentuk presentasi dalam sebuah seminar ilmiah, maupun dalam bentuk jurnal ilmiah. Sebelum memasuki proses seleksi, artikel ilmiah tersebut dipilah sesuai dengan kompetensi yang dimiliki oleh tim penilai. Umumnya proses pemilahan artikel ilmiah dilakukan secara manual oleh panitia pengelola seminar ilmiah, sehingga membutuhkan waktu dan membutuhkan ketepatan dalam penentuan tim penilai yang sesuai dengan artikel ilmiah. Pemilahan artikel ilmiah dapat dilakukan dengan menerapkan algoritma string similarity, yaitu dengan mencari kata-kata kunci yang terdapat dalam sebuah karya ilmiah. Kata kunci yang berada dalam artikel yang dihasilkan berdasarkan frekuensi kata yang muncul. Sebelum dicari kata yang banyak muncul, dilakukan proses filtering untuk menghilangkan kata sambung yang sering muncul sehingga tidak dianggap sebagai kata kunci artikel. Filtering menggunakan data stopword list yang digunakan oleh Tala. Sistem dibangun dalam bentuk aplikasi web menggunakan bahasa pemrograman PHP dan database MySQL dengan teknik responsive web design. Hasil penelitian ini menjelaskan bahwa artikel yang dimasukkan ke dalam sistem dapat dihasilkan kembali kata kunci yang sesuai dengan mendata kata-kata yang banyak muncul.
Kuesioner Online Sebagai Media Feedback Terhadap Pelayanan Akademik pada STMIK Prabumulih
Authors: Muchlis Muchlis , Christian Andi , Sari Mariana Puspa
Published: March 2019

Perguruan tinggi harus memberikan pelayanan yang baik terhadap kebutuhan mahasiswa dan dosen. Umpan balik pelayanan akademik perlu dievaluasi. Evaluasi pelayanan yang telah dilakukan  pada STMIK Prabumulih adalah dengan menyebarkan kuesioner secara konvensional. Kendala penggunaan kuesioner secara konvensional, yaitu perhitungan yang dilakukan secara manual. Hal ini menimbulkan adanya kesalahan dalam perhitungan dan pemasukan data. STMIK Prabumulih juga harus menyediakan kuesioner dalam bentuk kertas. Mahasiswa maupun dosen merasa enggan untuk menjawab kuesioner dalam bentuk kertas. Untuk mengatasi permasalahan tersebut, maka perlu dibangun sistem informasi kuesioner online berbasis website sehingga responden dapat mengisi kuesioner di mana pun dan kapan pun. Metode yang digunakan dalam pengembangan sistem  adalah metode waterfall dengan tahapan system engineering, analysis, design, coding, testing, dan maintenance. Pengujian sistem menggunakan pengujian black box. Hasil dari pengujian black box menunjukkan keseluruhan kebutuhan fungsional dapat berjalan dengan baik sesuai dengan kebutuhan dan sistem dapat berjalan dengan baik.
Perancangan Sistem Pakar Fuzzy Multi-Attribute Decision Making Psychological Distress pada Generasi Millennials
Authors: Ningrum Putri Taqwa , Yunanto Anggo Luthfi , Yuniasanti Reny
Published: March 2019

Psychological distress adalah keadaan subjektif yang dipresepsikan tidak menyenangkan. Setiap manusia tidak bisa menghindari dari gejala psychological distress yang meliputi depresi kecemasan ataupun stress, termasuk pada generasi millenials Generasi millennials cenderung lebih tidak peduli terhadap keadaan sosial di sekitar mereka seperti dunia politik ataupun perkembangan ekonomi Indonesia. Maka dari itu diperlukan suatu sistem yang dapat membantu dalam mengatasi Psychological distress. Sistem yang dibangun menggunakan metode Fuzzy Multi-Attribute Decision Making. Metode ini merupakan sebuah metode pengambilan keputusan untuk menetapkan alternatif terbaik dari sejumlah alternatif berdasarkan kriteria tertentu. Keluaran sistem berupa hasil diagnosa yang dapat memberikan beberapa alternatif emosional sesuai dengan pernyataan yang dimasukkan oleh pengguna. Sehingga dapat membantu pengguna dalam pengambilan keputusan. Metode Fuzzy Multi-Attribute Decision Making(FMADM) yang digunakan menghasilkan nilai yang identik antara perhitungan manual dengan perhitungan matematis oleh sistem, serta memperoleh nilai kecocokan perhitungan kuesioner dari pakar dan perhitungan FMADM sebesar 95%.
ANALISA KEBUTUHAN SILABUS BAHASA INGGRIS I MAHASISWA PERBANKAN SYARIAH BERBASIS ESP
Authors: Putri Hilma Pami
Published: March 2019

English is a compulsory subject that must be studied by all students, including students of Islamic Banking. Various efforts have been made by the lecturers so that the learning of English is interesting and attractive to students, including designing learning for the specific purposes (English for Specific Purposes). However, students are still having difficulties and have not had a good output after learning it. In addition, the material provided seemed unattractive to students. It was because of the material provided is not based on students’ needs. This research is a descriptive research by using a qualitative approach to see students' needs for English.The data was taken in the form of qualitative data, the utterances from interviews with respondents. In addition, quantitative data was taken from questionnaires distributed to Islamic Banking students related to the needs analysis of the English syllabus. The questionnaire consisted of learning need which was divided into input, procedure, setting, teacher's role, and learners' role. From the results of the research, it was found that students have their own learning needs for the material taught to them. Their learning needs must be realized in the learning plan in order to the goals of English can be achieved well.

Keywords: Learning Need, Need Analysis, ESP
STRATEGI PEMASARAN AGEN ASURANSI PRULINK SYARIAH DI KABUPATEN JEPARA
Authors: Susilo Edi , Nikmah Maghfirotun
Published: March 2019

This study aims to analyze insurance agent marketing strategies to get new customers of Sharia Prulink Insurance in Jepara Regency. The study used descriptive analytical qualitative methods. Data obtained by observation, interviews, literature studies, documentation, data processing, data presentation, and conclusions. The results of the study show that the insurance agent's strategy to get new customers is to maintain a cycle: Planning, Prospects, Approaches, Fact Finding, Presentation, Dealing with objections and Closing. To maintain and improve customers, insurance agents take steps: know your costomer (KYC), visit customers regularly; explain the benefits of insurance, serve excellence, willingness to serve customers who need help for their insurance, and awards on customers' birthdays.