bluuebunny/crossref_metadata_2025 huggingface dataset:
An end-to-end seizure prediction approach using long short-term memory network
Authors: Wu Xiao , Yang Zhaohui , Zhang Tinglin , Zhang Limei , Qiao Lishan
Published: May 2023

There are increasing epilepsy patients suffering from the pain of seizure onsets, and effective prediction of seizures could improve their quality of life. To obtain high sensitivity for epileptic seizure prediction, current studies generally need complex feature extraction operations, which heavily depends on the artificial experience (or domain knowledge) and is highly subjective. To address these issues, in this paper we propose an end-to-end epileptic seizure prediction approach based on the long short-term memory network (LSTM). In the new method, only the gamma band of raw electroencephalography (EEG) signals is extracted as network input directly for seizure prediction, thus avoiding subjective and expensive feature design process. Despite its simplicity, the proposed method achieves the mean sensitivity of 91.76% and false prediction rate (FPR) of 0.29/h on Children’s Hospital Boston-MIT (CHB-MIT) scalp EEG Database, respectively, when identifying the preictal stage from the EEG signals. Furthermore, different from traditional methods that only consider the classification of preictal and interictal EEG, we introduce the postictal stage as an extra class in the proposed method. As a result, the performance of seizure prediction is further improved, obtaining a higher sensitivity of 92.17% and a low FPR of 0.27/h. The mean warning time is 44.46 min, which suggests that sufficient time is reserved for patients to take intervention measures by this prediction method.
Biological functions of the Olig gene family in brain cancer and therapeutic targeting
Authors: Szu Jenny I. , Tsigelny Igor F. , Wojcinski Alexander , Kesari Santosh
Published: May 2023

The Olig genes encode members of the basic helix–loop–helix (bHLH) family of transcription factors. Olig1, Olig2, and Olig3 are expressed in both the developing and mature central nervous system (CNS) and regulate cellular specification and differentiation. Over the past decade extensive studies have established functional roles of Olig1 and Olig2 in development as well as in cancer. Olig2 overexpression drives glioma proliferation and resistance to radiation and chemotherapy. In this review, we summarize the biological functions of the Olig family in brain cancer and how targeting Olig family genes may have therapeutic benefit.
Shortwave infrared fluorescence imaging of peripheral organs in awake and freely moving mice
Authors: Arús Bernardo A. , Cosco Emily D. , Yiu Joycelyn , Balba Ilaria , Bischof Thomas S. , Sletten Ellen M. , Bruns Oliver T.
Published: May 2023

Extracting biological information from awake and unrestrained mice is imperative to in vivo basic and pre-clinical research. Accordingly, imaging methods which preclude invasiveness, anesthesia, and/or physical restraint enable more physiologically relevant biological data extraction by eliminating these extrinsic confounders. In this article, we discuss the recent development of shortwave infrared (SWIR) fluorescent imaging to visualize peripheral organs in freely-behaving mice, as well as propose potential applications of this imaging modality in the neurosciences.
Alignment of magnetic sensing and clinical magnetomyography
Authors: Ghahremani Arekhloo Negin , Parvizi Hossein , Zuo Siming , Wang Huxi , Nazarpour Kianoush , Marquetand Justus , Heidari Hadi
Published: May 2023

Neuromuscular diseases are a prevalent cause of prolonged and severe suffering for patients, and with the global population aging, it is increasingly becoming a pressing concern. To assess muscle activity in NMDs, clinicians and researchers typically use electromyography (EMG), which can be either non-invasive using surface EMG, or invasive through needle EMG. Surface EMG signals have a low spatial resolution, and while the needle EMG provides a higher resolution, it can be painful for the patients, with an additional risk of infection. The pain associated with the needle EMG can pose a risk for certain patient groups, such as children. For example, children with spinal muscular atrophy (type of NMD) require regular monitoring of treatment efficacy through needle EMG; however, due to the pain caused by the procedure, clinicians often rely on a clinical assessment rather than needle EMG. Magnetomyography (MMG), the magnetic counterpart of the EMG, measures muscle activity non-invasively using magnetic signals. With super-resolution capabilities, MMG has the potential to improve spatial resolution and, in the meantime, address the limitations of EMG. This article discusses the challenges in developing magnetic sensors for MMG, including sensor design and technology advancements that allow for more specific recordings, targeting of individual motor units, and reduction of magnetic noise. In addition, we cover the motor unit behavior and activation pattern, an overview of magnetic sensing technologies, and evaluations of wearable, non-invasive magnetic sensors for MMG.
Heterotopic connectivity of callosal dysgenesis in mice and humans
Authors: Szczupak Diego , Lent Roberto , Tovar-Moll Fernanda , Silva Afonso C.
Published: May 2023

The corpus callosum (CC), the largest brain commissure and the primary white matter pathway for interhemispheric cortical connectivity, was traditionally viewed as a predominantly homotopic structure, connecting mirror areas of the cortex. However, new studies verified that most callosal commissural fibers are heterotopic. Recently, we reported that ~75% of the callosal connections in the brains of mice, marmosets, and humans are heterotopic, having an essential role in determining the global properties of brain networks. In the present study, we leveraged high-resolution diffusion-weighted imaging and graph network modeling to investigate the relationship between heterotopic and homotopic callosal fibers in human subjects and in a spontaneous mouse model of Corpus Callosum Dysgenesis (CCD), a congenital developmental CC malformation that leads to widespread whole-brain reorganization. Our results show that the CCD brain is more heterotopic than the normotypical brain, with both mouse and human CCD subjects displaying highly variable heterotopicity maps. CCD mice have a clear heterotopicity cluster in the anterior CC, while hypoplasic humans have strongly variable patterns. Graph network-based connectivity profile showed a direct impact of heterotopic connections on CCD brains altering several network-based statistics. Our collective results show that CCD directly alters heterotopic connections and brain connectivity.
Predictive value of prognostic nutritional and systemic immune-inflammation indices for patients with microsatellite instability-high metastatic colorectal cancer receiving immunotherapy
Authors: Yi Jiahong , Xue Ju , Yang Lin , Xia Liangping , He Wenzhuo
Published: May 2023

Background

The prognostic nutritional index (PNI) and systemic immune-inflammation index (SII) are indicators of nutritional immune status. They have been reported associated with clinical outcomes of various solid tumors. However, it is unclear whether they can serve as predictors for patients with microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC) receiving immunotherapy. Our objective was to study the prognostic value of PNI and SII in these patients.

Methods

Seventy-five MSI-H mCRC patients were enrolled in our study. Logistic regression analysis was used to identify features that influenced immunotherapy response. Survival differences between groups of mCRC patients were compared using the Kaplan–Meier method and log-rank test. The independent risk parameters for progression-free survival (PFS) and overall survival (OS) of patients with MSI-H mCRC were established by Cox proportional risk regression analysis.

Results

The optimal SII and PNI cutoff values were 409.6 and 51.35. Higher PNI (p = 0.012) and lower high-density lipoprotein cholesterol (HDLC, p = 0.012) were associated with a better immunotherapy response. SII (p = 0.031), cholesterol (CHO) (p = 0.007) and aspartate aminotransferase (AST) (p = 0.031) were independent prognostic factors correlated with OS. Higher PNI (p = 0.012) and lower AST (p = 0.049) were negative predictors of PFS. In addition, patients suffered from immune-related adverse events (irAEs) had a lower SII level (p = 0.04).

Conclusion

Higher AST and SII, and lower PNI predict worse outcomes in MSI-H mCRC patients undergoing immunotherapy. Moreover, patients with lower SII before immunotherapy suffered from irAEs more often.
Nutrition, lifestyle, and cognitive performance in esport athletes
Authors: Goulart Jenna B. , Aitken Logan S. , Siddiqui Saman , Cuevas Marisa , Cardenas Jacqueline , Beathard Karen M. , Riechman Steven E.
Published: May 2023

Introduction

Electronic sports, termed esports, is a growing athletic activity in which high levels of attention and cognitive performance are required. With its increasing popularity and competitiveness, interest in strategies to improve performance have emerged. Improving esports athlete performance, namely cognitive endurance, and resilience, may lie in nutritional or lifestyle factors. The Nutrition, Vision, and Cognition in Sport Studies (IONSport) investigated nutritional and behavioral factors that can influence cognition via 3-dimensional multiple objects tracking test (3DMOT) via Neurotracker X (NTx) software. The purpose of this study was to characterize the lifestyle of high level esports athletes with detailed nutrition, sleep, and physical activity assessments, and their association to gaming related cognitive performance.

Methods

103 male and 16 elite female esports athletes aged 16 to 35 years old completed surveys, food records, and cognitive testing sessions over 10 days. Participants were instructed to maintain their normal dietary and lifestyle habits.

Results

There were positive significant associations between average NTx scores and the following nutrients: magnesium, phosphorous, potassium, sodium, zinc, selenium, thiamin, niacin, vitamins B6 and B12, folate, cholesterol, saturated, polyunsaturated, and monounsaturated fats, omega-6 and omega-3 fatty acids, and choline. Majority of participants did not meet recommended dietary allowances (RDAs) for these micronutrients nor the recommended intakes for dairy, fruit, and vegetables. There was a significant (p = 0.003) positive (r = 0.272) association between total vegetable intake and average NTx score. There was a significant negative association (p = 0.015) with our final sustain session, which measured cognitive resilience, and the Stanford Sleepiness Scale score. Repeated measures analysis was done with these groups over the 18 core NTx sessions. There were significant (p = 0.018) differences between the two groups with those who consumed the recommended amount of protein or more performing significantly better on NTx over the 18 sessions than those that did not consume enough protein. Those who consumed the recommended intakes for riboflavin, phosphorous, vitamin B12, and selenium performed significantly better over the 18 core NTx sessions than those that did not meet the recommended amounts.

Discussion

The need for a nutrition intervention that is rich in protein, vitamins, and minerals is warranted in this population.
Prevalence of vitamin D deficiency and associated risk of all-cause and cause-specific mortality among middle-aged and older adults in the United States
Authors: Wang Ting-Yi , Wang Hung-Wei , Jiang Ming-Yan
Published: May 2023

Introduction

The prevalence of vitamin D deficiency varied among populations and regions worldwide. In addition, the association between vitamin D deficiency and health outcomes remained controversial. Our study aimed to investigate the prevalence of vitamin D deficiency and its association with mortality risk among non-institutional middle-aged and older adults in the United States.

Method

The study population included 11,119 adult participants aged between 50 and 79 years in the 2007–2016 National Health and Nutrition Examination Survey (NHANES). Vitamin D status was divided as ≤ 30 (severely deficient), 30.1–50 (moderately deficient), 50.1–75 (insufficient), 75.1–100 (sufficient), and > 100 nmol/L (very sufficient). NHANES data were linked to National Death Index to ascertain the survival status and cause of death.

Results

The population aged 61.5 years (survey-weighted) and 47.9% were men. Among them, 4.6% were severely vitamin D deficient, 15.2% moderately deficient, and 33.6% insufficient. Individuals with higher vitamin D levels tended to be female, older, white people, non-smoker, non-single, more educated, with higher family income, and lower body mass index. During a median follow-up of 97.0 months, a total of 1,585 participants died (15.9 per 10,000 person-months). The crude analysis showed that vitamin D deficiency, but not vitamin D insufficiency, correlated to higher all-cause mortality risk. The association remained similar after adjusting for potential confounders, showing that vitamin D deficiency (HR: 1.38, 95% CI 1.15–1.66), but not vitamin D insufficiency (HR: 1.03, 95% CI 0.88–1.20), correlated to higher all-cause mortality risk. In addition, we showed that vitamin D deficiency was an independent risk factor for death from pneumonia (HR: 3.82, 95% CI 1.14–12.86) but not from cardiovascular diseases, cancer, or cerebrovascular diseases.

Conclusion

In summary, among middle-aged and older adults in the United States, nearly 20% were vitamin D deficient. Vitamin D deficiency, but not vitamin D insufficiency, correlated to increased mortality risk.
Bibliometric and visualized analysis of drug resistance in ovarian cancer from 2013 to 2022
Authors: Liu Jiahua , Ma Junnan , Zhang Jiarong , Li Chengming , Yu Bowen , Choe Hyok Chol , Ding Kaiyue , Zhang Liu , Zhang Lin
Published: May 2023

Objective

As one of the cancers that seriously threatens women’s health, ovarian cancer has a high morbidity and mortality rate. Surgery and chemotherapy are the basic treatment strategies for ovarian cancer, and chemotherapy resistance is a significant factor in affecting the prognosis, survival cycle, and recurrence of ovarian cancer. This article aims to analyze articles about ovarian cancer and drug resistance via bibliometric software, offering new ideas and directions for researchers in this field.

Methods

Both Citespace and Vosviewer are bibliometric software on the Java platform. Articles were collected on ovarian cancer and drug resistance in the Web of Science Core Collection database from 2013 to 2022. The countries, institutions, journals, authors, keywords, and references were analyzed, and the development status of this field was indicated from multiple perspectives.

Results

Studies on ovarian cancer and drug resistance generally showed an increasing trend from 2013 to 2022. The People’s Republic of China and Chinese institutions contributed more to this field. Gynecologic Oncology published the most articles, and the journal with the most citations was Cancer Research. Li Li was the author with the most publications, and Siegel RL was the author with the most citations. Through burst detection, it can be found that the research hotspots in this field mainly focused on the in-depth exploration of the drug resistance mechanism of ovarian cancer and the progress of PARP inhibitors and bevacizumab in the treatment of ovarian cancer.

Conclusions

Many studies on the mechanism of drug resistance in ovarian cancer have been discovered; however, the deeper mechanism remains to be explored. Compared with traditional chemotherapy drugs, PARP inhibitors and bevacizumab have shown better efficacy, but PARP inhibitors have initially shown drug resistance. The future direction of this field should be to overcome the resistance of existing drugs and actively develop new ones.
Screening of immunotherapy-related genes in bladder cancer based on GEO datasets
Authors: Liu Xiaolong , Li Xinxin , Kuang Qihui , Luo Hongbo
Published: May 2023

Background

As one of the most prevalent genitourinary cancers, bladder cancer (BLCA) is associated with high morbidity and mortality. Currently, limited indicators are available for early detection and diagnosis of bladder cancer, and there is a lack of specific biomarkers for evaluating the prognosis of BLCA patients. This study aims to identify critical genes that affect bladder cancer immunity to improve the diagnosis and prognosis of bladder cancer and to identify new biomarkers and targets for immunotherapy.

Methods

Two GEO datasets were used to screen differentially expressed genes (DEGs). The STRING database was used to construct a protein-protein interaction network of DEGs, and plug-in APP CytoHubba in Cytoscape was used to identify critical genes in the network. GO and KEGG analyses explored the functions and pathways of differential gene enrichment. We used GEPIA to validate the expression of differential genes, their impact on patient survival, and their relationship to clinicopathological parameters. Additionally, hub genes were verified using qRT-PCR and Western blotting. Immune infiltration analysis and multiple immunohistochemistry reveal the impact of Hub genes on the tumor microenvironment.

Result

We screened out 259 differential genes, and identified 10 key hub genes by the degree algorithm. Four genes (ACTA2, FLNA, TAGLN, and TPM1) were associated with overall or disease-free survival in BLCA patients and were significantly associated with clinical parameters. We experimentally confirmed that the mRNA and protein levels of these four genes were significantly decreased in bladder cancer cells. Immunoassays revealed that these four genes affect immune cell infiltration in the tumor microenvironment; they increased the polarization of M2 macrophages.

Conclusion

These four genes affect the tumor microenvironment of bladder cancer, provide a new direction for tumor immunotherapy, and have significant potential in the diagnosis and prognosis of bladder cancer.
OECD-407 Driven 28-day-repeated-dose non-clinical safety evaluation of Tinospora cordifolia (Giloy) stem aqueous extract in Sprague-Dawley rats under GLP compliance
Authors: Balkrishna Acharya , Haldar Swati , Varshney Anurag
Published: May 2023

Introduction:Tinospora cordifolia (Wild.) Hook.f. & Thomson (Giloy), has been widely used in the Ayurvedic system of medicine. However, some sporadic under-powered case studies have recently reported Tinospora cordifolia associated toxicity. Thus, following OECD 407 guidelines, a 28-day-repeated-dose-14-day-recovery toxicological evaluation of the aqueous extract of T. cordifolia stem (TCWE) was conducted under good laboratory practice (GLP), in Sprague-Dawley (SD) rats.

Methods: 100, 300, and 1000 mg/kg/day of TCWE was given orally to designated treatment groups of either sex. Two separate 14-day recovery satellite groups received either vehicle control or 1000 mg/kg/day of TCWE.

Results: In this study, TCWE was found safe up to a dose of 1000 mg/kg/day with no mortality or related toxicological manifestation in terms of clinical signs, ocular effects, hematology, urinalysis, clinical chemistry parameters, or macro- or microscopic changes in any organs. The satellite group did not show any adverse effect after 14-day recovery period. Thus, the No-Observed-Adverse-Effect-Level (NOAEL) of TCWE was determined to be 1000 mg/kg/day.

Discussion: In conclusion, this study established the non-clinical safety of the aqueous extract of T. cordifolia stem, which confirms the age-old safe medicinal use of this herb, and also paves the path for future clinical research on formulations containing Tinospora cordifolia.
Optimization of embryonic thermal programming confirms increased liver fattening in mule ducks and changes in lipid metabolism
Authors: Andrieux C. , Marchand M. , Larroquet L. , Veron V. , Biasutti S. , Morisson M. , Coustham V. , Panserat S. , Houssier M.
Published: May 2023

Introduction: The embryonic thermal programming (TM) in birds has been shown to impact several physiological parameters such as resistance to thermal stress, muscle growth or immunity. In mule ducks, it has recently been shown that TM can induce metabolic programming resulting in increased liver weight and fat storage after overfeeding. However, a decrease in hatchability and foie gras quality was also observed, suggesting that this technique needs to be optimized. Here, we tested a new thermal manipulation condition determined with the objective of avoiding negative impacts while maintaining or improving liver properties.

Methods: The eggs of the control group were incubated at 37.6°C during the whole incubation period while those of the experimental group (TM group) were incubated at 39.3°C 16 h/24 h from the 11th day of incubation to the 21st. After hatching, all the animals were fed and raised under the same conditions until the age of 12 weeks. At this stage, one part of the animals was overfed and then slaughtered 2 h (to measure rapid changes in metabolism) or 10 h after the last meal (to obtain the best technological yields), while the other part was ration-fed and slaughtered 2 h after the last meal, at the same age.

Results: An 8% increase in foie gras production was measured in the TM group compared to the control group without altering the quality of the final product (nor hatchability), confirming the successful optimization of the metabolic programming. Interestingly, these results allowed us not to reject the previously suggested hypothesis of a potential delay in metabolic processes involved in liver fattening in programmed animals, in particular by measuring a trend reversal regarding the amount of total hepatic lipids in both groups at 2 h and then 10 h after the last meal.

Discussion: This study therefore validates the optimization of metabolic programming by embryonic thermal manipulation for duck liver fattening. The understanding of the mechanisms of embryonic thermal programming in birds remains today very incomplete and the search for epigenetic marks (main hypothesis of the concept of programming) at the origin of the observed phenotypes could be the next step of this work.
Non-cognitive skills and immigrant-native inequalities in the labor market in Europe
Authors: Kanas Agnieszka , Fenger Menno
Published: May 2023

Non-cognitive skills are increasingly essential in the labor market, especially given technological advances and evolving work environments. Unequal distribution of non-cognitive skills among various groups in the population may contribute to labor market inequalities. This article investigates the significance of non-cognitive skills for immigrant-native inequalities in the European labor market. Specifically, we examine the potential differences in non-cognitive skills between native and immigrant groups and how these differences may affect their income. Additionally, we explore whether equal levels of non-cognitive skills have comparable payoffs for native and immigrant groups in society. We use, comparative survey data from the Programme for the International Assessment of Adult Competencies and OLS regressions with country fixed effects. Our findings show that many immigrants exhibit lower levels of non-cognitive skills than native-born workers, despite differences between origin groups. This difference in non-cognitive skills explains part of the immigrant-native inequality in the labor market for most immigrant-origin groups. Moreover, our results indicate that immigrants, especially those from Central and Eastern European countries, benefit less from exercising comparable non-cognitive skills than native-born workers. Our study highlights the importance of non-cognitive skills in addressing the labor market disadvantage faced by immigrants, and emphasizes that policymakers and educators should recognize the significance of these skills when developing policies targeting immigrants.
Evaluating blended learning effectiveness: an empirical study from undergraduates’ perspectives using structural equation modeling
Authors: Han Xiaotian
Published: May 2023

Following the global COVID-19 outbreak, blended learning (BL) has received increasing attention from educators. The purpose of this study was: (a) to develop a measurement to evaluate the effectiveness of blended learning for undergraduates; and (b) to explore the potential association between effectiveness with blended learning and student learning outcomes. This research consisted of two stages. In Stage I, a measurement for evaluating undergraduates’ blended learning perceptions was developed. In Stage II, a non-experimental, correlational design was utilized to examine whether or not there is an association between blended learning effectiveness and student learning outcomes. SPSS 26.0 and AMOS 23.0 were utilized to implement factor analysis and structured equation modeling. The results of the study demonstrated: (1) The hypothesized factors (course overview, course objectives, assessments, 1148 class activities, course resources, and technology support) were aligned as a unified system in blended learning. (2) There was a positive relationship between the effectiveness of blended learning and student learning outcomes. Additional findings, explanations, and suggestions for future research were also discussed in the study.
How past trauma impacts emotional intelligence: Examining the connection
Authors: Gottfredson Ryan K. , Becker William J.
Published: May 2023

Backed by both research and practice, the organizational psychology field has come to value emotional intelligence (EI) as being vital for leader and employee effectiveness. While this field values EI, it has paid little attention to the antecedents of emotional intelligence, leaving the EI domain without clarity on (1) why EI might vary across individuals, and (2) how to best develop EI. In this article, we rely on neuroscience and psychology research to make the case that past psychological trauma impacts later EI capabilities. Specifically, we present evidence that psychological trauma impairs the brain areas and functions that support EI. Establishing psychological trauma has valuable theoretical and practical implications that include providing an explanation of why EI might vary across individuals and providing a focus for improving EI: healing from past trauma. Further theoretical and practical implications for the field of organizational psychology are provided.
Future horizons in the analysis of technical-tactical performance in women’s football: a mixed methods approach to the analysis of in-depth interviews with professional coaches and players
Authors: Iván-Baragaño Iyán , Ardá Antonio , Anguera M. Teresa , Losada José Luis , Maneiro Rubén
Published: May 2023

Introduction

Scientific knowledge about the criteria that determine success in women’s football is beginning to develop.

Methods

This study was carried out with the aim of detecting regularities in the offensive success in elite women’s football, as well as carrying out an interrelational analysis of linked behaviors, based on in-depth interviews with professional coaches and players. Eight in-depth interviews were conducted with professional Spanish coaches and players. The interviews were analyzed by indirect observation from a process of “quantitizing,” through the construction of an indirect observation ad hoc instrument. The segmentation of the transcription of the interviews was carried out in textual units, and the creation of a matrix of codes. Two types of analysis were performed: first, a lag sequential analysis (LSA) was performed and, then, a polar coordinates analysis (PCA), which allowed to find, respectively, a wide number of established communicative patterns with offensive performance in women’s football, as well as an interrelational map between the established codes.

Results

The results obtained allowed us to suggest a statistically significant association between success in women’s football and criteria such as the physical characteristics of a particular player, the individual action space, the duration of the attack, the type of dynamic start, individual and collective technical and tactical aspects, decision making and the type of attack used.

Discussion

Based on these results, the influence of these criteria on performance in women’s soccer can be studied in future studies. In addition, with the aim of increasing the validity of these conclusions, new studies on this subject may be carried out following strategies such as the Delphi Method.
Work values and cultural background: a comparative analysis of work values of Chinese and British engineers in the UK
Authors: Shi Ziteng , Huang Wei , Liang Yuhui
Published: May 2023

In literature of work-related values and attitudes, it is often argued that different work attitudes could be attributed to different ethnic origins and cultural backgrounds. This perspective article argues that we should avoid a deterministic argument of cultural essentialism and explore how ethnic differences in work values were formed in specifical socioeconomic and cultural contexts. To support this argument, this research conducted in-depth interviews to explore the mechanisms underlying the formation of British and Chinese immigrant engineers’ work values in three dimensions: intrinsic-extrinsic, masculine-feminine, uncertainty avoidance-entrepreneurial risk. The main finding in this paper is that the different social and cultural milieus where both ethnic groups grew up to a large extent contributed to their different work habitus, which further resulted in their different work values. To conclude, this paper contributes to the literature by rejecting the cultural essentialism, which links individual work attitudes with their ethnic/cultural backgrounds in a “deterministic” way.
Parental phubbing and academic burnout in adolescents: the role of social anxiety and self-control
Authors: Jiang Yuqian , Lin Lu , Hu Ronghua
Published: May 2023

Based on the limited resource model of self-control, we construct a chain mediation model to examine the relationship between parental phubbing and adolescents’ academic burnout, and whether social anxiety and self-control play a mediating role in it. We used 4 questionnaires to investigate parental phubbing, social anxiety, self-control, and adolescents’ academic burnout among 828 high school students in Wuhu and Huangshan City, Anhui Province, China. The findings indicated that: (1) parental phubbing, social anxiety, and self-control all significantly predict adolescents’ academic burnout directly and (2) parental phubbing could indirectly influence adolescents’ academic burnout through three pathways: the separate mediating effect of social anxiety and self-control, and the chain mediating effect on both. The results of this study help parents understand how their phubbing actions affect adolescents’ academic burnout and the mechanism of action.
Beyond the global attachment model: domain- and relationship-specific attachment models at work and their functions
Authors: Greškovičová Katarína , Lisá Elena
Published: May 2023

Introduction

Since prior research has shown the importance of specific attachment models, we wanted to explore specific adult attachments (colleagues, leader, and workplace) in the working setting. The study aimed to investigate the position of specific adult attachments in the attachment hierarchy and their associations with various organizational variables. Finally, we assumed that dimensions of the colleagues-domain attachment model would cluster into attachment types at work, according to secure, preoccupied, and avoidant attachment orientations.

Methods

We carried out cross-sectional time-lagged research design. The sample consisted of 1,352 participants based on convenience and voluntary sampling procedures. Participants aged 18–78 worked in various work teams and positions. The battery consisted of the Adult Attachment in the Workplace Questionnaire, the Workplace Attachment Styles Questionnaire, the Scale of Belonging to the Organization, the Leader as Security Provider Scale, the shortened Experiences in Close Relationships-Revised Questionnaire, the Czech Leadership Questionnaire, the Citizenship Organizational Behavior Questionnaire, the General Work Performance questionnaire, the Utrecht Work Engagement Scale. Data were analyzed in JASP 0.16.3 and IBM SPSS Statistics 22. Among other statistical methods, we performed factor analysis and two-step cluster analysis. The alpha level for statistical testing was set to 0.05.

Results

The results show that the work-specific attachment models differ from the romantic domain attachment model. Moreover, the work-specific attachment models also differ among themselves. Depending on the attachment to colleagues, it is possible to distinguish two attachment orientations (secure and insecure) among working adults. These two types differ in all the variables studied (relationships with colleagues, romantic partners, belonging to people and place, and performance).

Conclusion

The study advances our knowledge of attachment working models and their application in the organizational context. We confirmed hierarchical attachment mental presentations and show the distinction in attachment working models at work. Colleagues and leaders form two separate domains within the workplace. Attachment to a leader is associated with the leadership style and secure workplace attachment. Attachment to colleagues might be more important in insecure workplace attachment and insecure belonging. Fostering secure attachment at work might bring together more positive outcomes for the company regarding performance and relationships at work.
Development and relationship between the judgment of the speed of passage of time and the judgment of duration in children
Authors: Martinelli Natalia N. , Droit-Volet Sylvie
Published: May 2023

This study examined the relationships between the awareness of the speed of the passage of time, the judgment of durations and experiential factors in children aged 4–9 years. They were asked to judge the duration and the speed of the passage of time for different intervals (second and minutes), and to rate their feelings (arousal, happiness, sadness, and task difficulty) during each interval. The results indicated that 8–9-year-olds’ judgment of the passage of time is extremely flexible and context-dependent, representing the duration and/or the individual changes in subjective experience (emotion). In contrast, young children’s judgment of the passage of time was not related to duration. However, their judgments were not given randomly. They judged that time passed more quickly when they felt happier and more alert. The passage-of-time judgment was therefore initially grounded in emotional and sensory-motor experience, i.e., in their perception of changes (acceleration and deceleration) in self-movement (successions of states and their extension). Therefore, duration judgment and passage-of-time judgment initially develop separately and are later combined when children understand the logical link between speed and duration.
Longitudinal assessment and determinants of short-term and longer-term psychological distress in a sample of healthcare workers during the COVID-19 pandemic in Quebec, Canada
Authors: Rapisarda Filippo , Bergeron Nicolas , Dufour Marie-Michèle , Guay Stéphane , Geoffrion Steve
Published: May 2023

Introduction

Previous research has demonstrated the negative impact of the COVID-19 pandemic emergency on the wellbeing of healthcare workers. However, few research contributions reported a longitudinal evaluation of psychological distress and examined determinants of its duration and course over time. The present study aims to explore the impact of the pandemic emergency on HCWs mental health by adopting a longitudinal design and assessing mental health as combination of overlapping clinical symptoms (post-traumatic stress disorder, depression and anxiety).

Methods

Data were collected weekly through a mobile application during and after the first wave of COVID-19 in the province of Quebec, Canada, in 2020. Analysis was conducted on a final sample of 382 participants. Participants were grouped into “resilient” (RES) if they did not manifest clinical-level psychological distress during monitoring, “short-term distress” (STD) if distress exceeded the clinical threshold for 1–3 weeks, and longer-term distress (LTD) if it occurred for four or more weeks, even if not consecutively. Descriptive statistics for all variables were computed for each subgroup (RES, STD and LTD), and pairwise comparisons between each group for every descriptive variable were made using chi square statistics for categorical variables and t-test for continuous variables. Predictors of distress groups (STD and LTD vs RES) were assessed running multinomial hierarchical logistic regression models.

Results

In our sample, almost two third (59.4%) HCWs did not manifest moderate or severe distress during the monitoring time. Short-term distress, mostly post-traumatic symptoms that lasted for less than 4 weeks, were the most common distress response, affecting almost one third of participants. Longer psychological distress occurred only in a smaller percentage (12.6%) of cases, as a combination of severe posttraumatic, depressive and anxiety symptoms. Perceived occupational stress was the most significant risk factor; moreover individual, peritraumatic work and family risk and protective factors, were likely to significantly affect the stress response.

Discussion

Results tend to provide a more complex and resiliency-oriented representation of psychological distress compared to previous cross-sectional studies, but are in line with stress response studies. Findings allow us to better describe the profiles of distress response in STD and LTD groups. Participants that manifest short term distress experience acute stress reaction in which the interplay between personal, family and professional life events is associated with the stress response. Conversely, longer term distress response in HCWs presents a more complex mental health condition with an higher level of impairment and support needs compared to participants with short-term distress.
Anxiety among hospitalized COVID-19 patients: a case–control study from a tertiary teaching hospital in Malaysia
Authors: Tan Hui Jan , Shahren Abdool Alleem Hj , Khoo Ching Soong , Ng Chen Fei , Zaidi Wan Asyraf Wan , Kori Najma , Periyasamy Petrick , Eu Choon Leng , Payus Alvin Oliver , Hod Rozita
Published: May 2023

Introduction

Anxiety has been increasingly recognized as part of the psychosocial health issues in COVID-19 patients. However, the impact of this topic may be underestimated in low- and middle-income countries. This study aimed to estimate the prevalence of and risk factors of anxiety in COVID-19 patients compared to controls in a local tertiary teaching hospital in Malaysia.

Methods

In this case–control study, we analyzed data on adult patients aged 18 years and above hospitalized for COVID-19 infection with matched hospitalized controls. The demographic, clinical data and anxiety measures using the Generalized Anxiety Disorder-7 questionnaire were analyzed using univariate and multivariate analysis.

Results

86.6% in the COVID-19 group had anxiety, significantly higher than 13.4% in the control group (p = 0.001). The COVID-19 group was significantly associated with the GAD-7 severity (p = 0.001). The number of COVID-19 patients in the mild, moderate, and severe anxiety groups was 48 (84.2%), 37 (86%), and 18 (94.7%), respectively. Multiple logistic regression showed significant predictors for anxiety, including COVID-19 diagnosis and neurological symptoms. Anxiety was found 36.92 times higher in the patients with COVID-19 compared to those without COVID-19 (OR 36.92;95% CI 17.09, 79.78, p = 0.001). Patients with neurological symptoms were at risk of having anxiety (OR 2.94; 95% CI 1.03, 8.41, p = 0.044).

Discussion

COVID-19 patients experience a significant disruption in psychosocial functioning due to hospitalization. The burden of anxiety is notably high, compounded by a diagnosis of COVID-19 itself and neurological symptomatology. Early psychiatric referrals are warranted for patients at risk of developing anxiety symptoms.
A voxel-based morphometry investigation of brain structure variations in late-life depression with insomnia
Authors: Shao Heng , Li Na , Chen Meiling , Zhang Jie , Chen Hui , Zhao Minjun , Yang Jingjing , Xia Jian
Published: May 2023

Background

Late-life depression (LLD) is linked to various medical conditions and influenced by aging-related processes. Sleep disturbances and insomnia symptoms may be early indicators or risk factors for depression. Neuroimaging studies have attempted to understand the neural mechanisms underlying LLD, focusing on different brain networks. This study aims to further delineate discriminative brain structural profiles for LLD with insomnia using MRI.

Methods

We analyzed 24 cases in the LLD with insomnia group, 26 cases in the LLD group, and 26 in the healthy control (HC) group. Patients were evaluated using the Hamilton Depression Rating Scale (HAMD-17), Hamilton Anxiety Rating Scale (HAMA), Mini-Mental State Examination (MMSE), and Pittsburgh Sleep Quality Index (PSQI). Structural MRI data were gathered and analyzed using voxel-based morphometry (VBM) to identify differences in gray matter volume (GMV) among the groups. Correlation analyses were conducted to explore the relationships between GMV and clinical characteristics.

Results

Significant difference in sex distribution was observed across the groups (p = 0.029). However, no significant differences were detected in age and MMSE scores among the groups. LLD with insomnia group exhibited significantly higher HAMA (p = 0.041) and PSQI scores (p < 0.05) compared to the LLD group. ANOVA identified significant difference in GMV of anterior lobe of cerebellum (peak MNI coordinate: x = 52, y = −40, z = −30) among HC, LLD, and LLD with insomnia. Post-hoc two-sample t-tests revealed that the significant difference in GMV was only found between the LLD group and the HC group (p < 0.05). The mean GMV in the cerebellum was positively correlated with HAMA scale in LLD patients (r = 0.47, p < 0.05).

Conclusion

There is significant difference in GMV in the LLD group, the association between late-life depression and insomnia may be linked to anxiety. This study provides insights into the discriminative brain structural profiles of LLD and LLD with insomnia, advancing the understanding of the underlying neural mechanisms and potential targets for intervention.
Reproductive decision-making following the diagnosis of an inherited metabolic disorder via newborn screening in Japan: a qualitative study
Authors: Hiromoto Kana , Nishigaki Masakazu , Kosugi Shinji , Yamada Takahiro
Published: May 2023

Introduction

The aim of the study was to describe the factors influencing the reproductive decision-making of carrier parents after the diagnosis of an inherited metabolic disorder in newborn screening in Japan.

Methods

We conducted a semi-structured interview with 12 parents and analyzed data based on content analysis methodology.

Results

We identified 11 factors, including personal evaluation of recurrence risk, understanding of hereditary phenomena, concerns and desires for future planned children, concerns for older siblings, perceptions of diseases, degree of acceptance and denial of diseases, the opinions of others on having another child, optimism/faith in positive outcomes, self-evaluation of parental capability, factors unrelated to the disease, and the “right” time to expand the family.

Discussion

Perceptions and acceptance of disease are both important factors in reproductive decision-making, though these factors fluctuate continuously during the childbearing period. Therefore, effective reproductive genetic counseling will be considerate of the parents' fluctuating perceptions on reproduction. To ensure that the decision-making process is for the benefit of the parents and future children, long-term involvement of health care professionals is needed to assess the client's acceptance of the disease and their understanding of genetic phenomena and recurrence rates.
Different positions in society, differing views of the world: the privatization of water and sanitation services in Minas Gerais, Brazil
Authors: Neves-Silva Priscila , Braga Juliana Gontijo , Heller Léo
Published: May 2023

Introduction

In 2020, the Brazilian government sanctioned Law No. 14.026, which established new guidelines for water and sanitation in the country and encouraged service privatization. Based on this, the State of Minas Gerais government, Brazil has proposed a bill for these services. Regarding this bill, different social actors in the State of Minas Gerais have expressed different assessments concerning the outcomes of the proposed management model and its impact on the realization of the human rights to safe water and sanitation.

Methods

We used content analysis techniques to assess the position of different actors—government, civil society, and private sector—in three public events that were recorded and posted on the YouTube platform.

Results

The analyses of this study indicated that the positions of the current government are aligned with those of the private sector. Also, the analyses agree that privatization can lead to the universalization of access to services. These different actors did not mention the human rights to safe water and sanitation in their discourses. Civil society organizations are concerned about the guarantee of those rights. For them, privatization of water and sanitation services can lead to discontinuation of the access of these services to vulnerable populations and poor municipalities due to tariff increases.

Discussion

The discourses concerning water and sanitation privatization as an instrument for universalization are disputed. Private sector actors and government representatives, aligned with the neoliberal agenda, support privatization. Civil society organizations defend the improvement of public management as the path to universalization. Representatives of municipalities were not included in the discussion for the new bill. The different societal positions relate to the different views these actors have concerning privatization and the world.
Pro-environmental employee engagement: the influence of pro-environmental psychological capital, pro-environmental job resources, and perceived corporate environmental responsibility
Authors: Albrecht Simon L. , Donnelly Teagan , Frenkiel Michael , Rajic Stefan K. , Kavadas Vicki , Leiter Michael P.
Published: May 2023

For organizations to achieve their environmental obligations and objectives, they need employees to actively engage with environmental policies, practices, procedures, and initiatives. Based on engagement theory, a model is proposed that shows how perceived corporate environmental responsibility, pro-environmental job resources, and pro-environmental psychological capital influence employee pro-environmental engagement at work. Survey responses were collected from a Prolific sample of 347 full-time and part-time employees, aged 18–80, working within Australian organizations across a range of occupations. Confirmatory factor analysis and structural equations modeling provided broad support for the measures and the relationships proposed in the model. The model explained 64% of the variance in pro-environmental job resources, 90% of the variance in pro-environmental psychological capital, and 92% of the variance in pro-environmental engagement. Overall, the results suggest that for employees to feel enthusiastic and involved in pro-environmental initiatives at work, an integrated approach that takes account of perceived corporate environmental responsibility, pro-environmental job resources, and pro-environmental psychological capital is required. The results also provide brief, defensible measures of pro-environmental PsyCap, pro-environmental job resources and pro-environmental engagement that can be used to assess and target employee attitudes toward pro-environmental initiatives and opportunities. As such, the pro-environmental engagement model can help guide the design and implementation of evidence-based employee-focused interventions that will help achieve environmental sustainability objectives.