bluuebunny/crossref_metadata_2025 huggingface dataset:
LNG system - Levonorgestrel 52 in dysfunctional uterine bleeding
Authors: KS Devane
Published: July 2023

My objective behind this study is to “save uterus” which is falling victim to the surgical treatment for dysfunctional uterine bleeding. In dysfunctional uterine bleeding levonorgestrel is a key drug which is given orally or intra muscularly which has many side effects and because of that patients fade up and demand hysterectomy for this benign condition. This is LNG system or intrauterine device delivering levonorgestrel at uterine endometrium. This study was carried out in the hospital “Varad Hospital”. Twenty five patients were included in this study after taking prior consent and after doing diagnostic curettage. Results were very promising. 88% of the patients got relief of the symptoms and happily continued it and even referred more clients for treatment. Conclusion: The Indian version of the “intrauterine LNG system” is cheaper, effective and easy to insert. Keywords: LNG IUS 52; levonorgestrel; levonorgestrel; DUB; dysfunctional uterine bleeding
Management of hyperglycemia in diabetics with cardiovascular disease
Authors: D Prasun , K Jaideep , KJ Ashish , RN Mehrotra
Published: July 2023

Diabetes mellitus is a syndrome characterized by hyperglycemia and dyslipidemia; and is associated with various systemic complications including acute metabolic emergencies and chronic complications, which includes microvascular and macrovascular manifestations. Coronary artery diseases are the major causes of morbidity and mortality. Various studies have convincingly demonstrated that managing hyperglycemia adequately is important for controlling diabetic complications, but macrovascular complications have not shown as significant reduction as have microvascular diseases. The cardiac safety of various anti-diabetic agents available to us also vary, which suggests that both euglycemia per se, as well the agent used to achieve it, are important considerations for cardiovascular safety. The Food and Drugs Administration of the United States of America has now stipulated that all anti-diabetic medications must undergo cardio-vascular outcome trials to prove cardiac safety before they are approved for use. Most currently available anti-diabetics are neutral on the heart, and may be continued safely in patients with chronic stable coronary artery disease (CAD). However, recent data from cardio-vascular outcome trials involving SGLT2-inhibitors and GLP1R-analogs demonstrate impressive cardiac safety data. Insulin still remains the agent of choice during recent acute coronary events and critical-care management. Keywords: diabetes mellitus; hyperglycemia; macrovascular complication; coronary artery diseases; cardio-vascular outcome trials
Okunev Culture and the Dene-Caucasian Macrofamily
Authors: Kozintsev A. G.
Published: July 2023

The article discusses the linguistic affi liation of the Okunev people. Arguments are cited favoring the idea that they spoke a Dene-Caucasian language belonging to the Yeniseian branch. This is indirectly evidenced by genetic and cultural ties between Okunev ancestors and Native Americans, by parallels to Okunev art in prehistoric China and on the northwestern coast of North America, and by Okunev type petroglyphs in northern Kashmir, where, in addition, a linguistic isolate is preserved—Burushaski, a language related to Yeniseian. Being a relict population, which remained in the place from where the Dene-Caucasian speaking tribes had migrated in various directions, Okunevans may have been ancestors of Yeniseians (another contender is the Karasuk population, whose ties with Okunevans remain to be established), as well as collateral relatives of Na-Dene, Sino-Tibetans, and other Dene- Caucasians. Alternative proposals, such as a Uralic, specifi cally Samoyed affi liation of the Okunev language, are less probable for several reasons. The idea that this language was Indo-Iranian, which almost necessarily follows from the hypothesis that the key role in Okunev origins was played by Yamnaya-Catacomb tribes, is quite unlikely. This idea is much more plausible with regard to Chaa-Khol people of Tuva, who display marked cranial affi nities with a number of Yamnaya and Catacomb groups and with Scythians of the Pontic steppes. Okunevans proper show no such affi nities.
Implementation of Lex Specialis in Sports Jurisdiction
Authors: Panagiotopoulos Dimitrios P.
Published: July 2023

The present study sets out the implementation of Lex Specialis in Sports Jurisdiction. It presents an introduction to Sports Law and the rules of Lex Sportiva and Lex Olympica. Following the introduction, this paper presents the concept of Sports Jurisdiction and the competence of the Sport Arbitral Bodies to rule on the constitutionality of the law. Furthermore, this study focuses on the necessity for the establishment of an International Sports Constitutional Charter with special rules for international sports activities and the establishment of a special International Sports Court. Finally, is investigated the application of the Lex Specialis Derogat Legi Generali Principle in Sports Law. In particular, this study points out that Special rules of sports law prevail over ordinary rules of law, according to the general principle of law Lex Specialis Derogat Legi Generali. It is highlighted that Sports Law is not a subcategory of international law, as International Sports Law, but a different kind of law, Lex Sportiva/Olympica. Lex Sportiva/ Olympica is an international “unethnical” law, which exists in parallel to the international law. It constitutes a sui generis sports law legal order, imposed heteronomously on the sporting world by various international organizations.
The Issue of Voluntariness of Consent to Refer Disputes to the Court of Arbitration for Sport based on the Analysis of Its Status and Principles of Functioning
Authors: Peshin N. L.
Published: July 2023

The article is devoted to the study of institutional and procedural problems related to the resolution of conflicts arising in professional and Olympic sports (elite sports). Modern sport seeks to isolate itself from state and international legal regulation, to create its own system of corporate standards, the subjects of which are sports organizations and athletes. In order to impart stability to the introduced system of corporate rules, international non-governmental organizations leading the world sports and Olympic movement also create their own jurisdictional bodies (arbitration courts, the so-called sports tribunals), the purpose of which is to resolve disputes between athletes, sports organizations on corporate rules established by international sports federations and the International Olympic Committee. The central part of this system of sports arbitration courts is the Sports Arbitration Court in Lausanne (Switzerland), whose status is analyzed in detail in this paper.One of the main problems to which the author pays attention, is the non-consensual, in fact forced nature of the spread of the jurisdiction of the sports arbitration courts on athletes, often combined with a prohibition (established in the corporate act — for example, the regulations of sports federations) to appeal to the state courts under a threat of lifelong disqualification. Thus, the structures that govern the world professional and Olympic sports require athletes to refuse to exercise their constitutional right to access to justice. But could an arbitration clause be considered valid if the athlete did not give consent to the consideration of his disputes in the arbitration court (arbitration) and to the choice of arbitration jurisdiction, which in fact was forced? Unfortunately, practice shows that in most cases, when athletes ignore this ban and apply to national courts, appealing against the decisions of the sports arbitration court in Lausanne, the latter make “political” decisions that take the interests of the leading forces in the world sports movement into account.
In Search of Clear Scientific Criteria for Including New Substances and Methods on the WADA Prohibited List
Authors: Norboeva T. V. , Zakharova L. I.
Published: July 2023

In the World Anti-Doping Code and in the practice of its application in the sports world, four criteria were elaborated to guide the process of including new substances and methods on the Prohibited List, namely representing an actual or potential risk to the health of athletes, enhancing sport performance, violating the spirit of sports, masking the use of other prohibited substances or prohibited methods. However, these criteria do not fully address the question of how the selection should be carried out when a substance or method is included on the Prohibited List. The approach according to which the presence of any two out of the three following criteria — enhancing sport performance, representing a risk to the health of athletes, violating the spirit of sports — in a specific case can hardly be considered exhaustive and definite (the fourth criterion — masking the use of other prohibited substances or methods — is self-evident). The authors identify new problems that need to be taken into account in the future. These are, in particular, the need to improve the decision-making procedure for including new substances and methods on the List and to make it more transparent and the need to normatively settle the issue of using new technological devices, more specifically nanotechnologies and nanomaterials (technological doping).
Environmental, social and governance scores in Europe: what drives financial performance for larger firms?
Authors: Gonçalves Tiago Cruz , Barros Victor , Avelar José Vicente
Published: July 2023

This paper aims to investigate the association between firms’ financial performance and their sustainability performance, as measured by Tobin's Q, with a focus on the individual ESG pillars. Our study analyzes constituents of the Stoxx Europe 600 index. We employ different econometric approaches and perform a comprehensive analysis of the post-2015 agreement concerning climate change. Results suggest a statistically positive relationship between firms’ ESG and financial performance, although of greater magnitude for the social component. Overall, our findings highlight the superior relevance of social performance in yielding shareholder value for the largest European firms.
CSR committee and firm value during the COVID-19 pandemic
Authors: Hsu Yu-Lin , Chu Ya-Ching
Published: July 2023

This paper investigates whether the presence of CSR committees has a mitigating effect on firm value (measured by Tobin’s Q) during the COVID-19 pandemic. Analyzing UK listed firm data, we find that although the pandemic results in lower firm value, the presence of CSR committees helps to mitigate the negative impact of COVID-19 on firm value. The results suggest that the formation of CSR committees is not a symbolic impression management tool but an effective sustainability governance mechanism during the crisis. Our results should be helpful for regulators and companies in making decisions related to CSR committees.
Department of Pharmacology of the Imperial Medical and Surgical (Military Medical) Academy: History of the second century of existence (1899–2000)
Authors: Shabanov Petr D.
Published: July 2023

The study presents the history of the development of the Department of Pharmacology of Medical and Surgical (since 1881 Military Medical) Academy with an emphasis on the second century of its existence (18992000). This period was marked by the improvement of both the teaching of the discipline, based on new pharmacological data, and the introduction of new methods of drug research. A significant event was the release of a two-volume edition of N.P. Kravkovs Fundamentals of Pharmacology in 19041905, which was based on the introduction of the latest achievements of scientific knowledge in the field of pharmacology. The textbook N.P. Kravkov withstood 14 editions (the last one was published in 1936, 12 years after the authors death) and served as a model for the creation of all subsequent domestic textbooks and manuals on pharmacology in the 20th century. In experimental pharmacology, the method of isolated organs (N.P. Kravkov et al.) has been widely used as a universal method for quantifying pharmacological effects. In the 1920s, ideas about the synaptic effect of drugs were actively introduced (S.V. Anichkov et al.), and the effects of N-cholinergic drugs realized through the sinocarotid zone of the carotid artery were discovered and studied. Biochemical studies began to be widely used, which started with the works of N.P. Kravkov and continued by N.V. Lazarev, V.M. Vinogradov, and A.V. Smirnov. Clinical pharmacology was created and promoted after the discovery and first use of the intravenous anesthetic hedonal (N.P. Kravkov), particularly developed in the studies by N.V. Lazarev and V.M. Vinogradov. New ideas about antihypoxants and actoprotectors were formulated (V.M. Vinogradov) to increase combat capability and was successfully used in military pharmacology at the end of the 20th century (V.M. Vinogradov and A.V. Smirnov). Therefore, with these achievements, the department has succeeded in both the academic and scientific fields.
The Effect of Combined Respiratory Muscle Training on Dysarthric Speech Following Single Cerebrovascular Accident: A Retrospective Pilot Study
Authors: Arnold Robert , Bausek Nina , Gaskill Christopher , Midani Tarek
Published: July 2023

Background: Dysarthria frequently occurs as a result of stroke and adversely impacts speech sound production, making it more difficult for the listener to understand what the person with dysarthria is attempting to communicate. This in turn may lead to social isolation, depression, and increased cost of care. Some studies have underscored the importance of respiratory muscle strengthening as it relates to improvement of speech intelligibility. This retrospective investigation examined the effects of a combined Respiratory Muscle Training (cRMT) protocol upon speech intelligibility in persons post single cerebrovascular accident (CVA). Methods: The clinical data of 10 patients who requested pro bono speech therapy for the diagnosis and treatment of dysarthria following a single stroke was utilized for this study. The intervention group was treated with three 5-minute sessions with cRMT each day for 28 consecutive days. The control group received no cRMT and no other therapeutic exercise intervention during the time period. Respiratory and speech intelligibility were assessed pre- and post-intervention in terms of peak expiratory flow, subject self-perception of intelligibility, and word level intelligibility. Results: After 28 days of cRMT, the intervention group (IG) exhibited significant gains compared to the control group (CG) in peak expiratory flow (PEF) (IG: 73.12% vs CG: 4.66%), Self-Perception of Intelligibility (IG: 72.38% vs CG: 0.83%), and the word task of the Assessment of Intelligibility of Dysarthric Speech (AIDS) (IG: 43.92% vs. CG: 0%). Conclusion: These data suggest cRMT is a feasible and effective treatment for improving breath support and speech intelligibility in persons with dysarthric speech.
Technique of the cardiac resynchronization therapy device implantation
Authors: Darciuc Radu
Published: July 2023

Introduction Cardiac resynchronization therapy has become an established treatment modality for patients with advanced heart failure and left bundle branch block. In 2016 we started the implantation of the CRT devices in Medpark International Hospital and for the first time in The Republic of Moldova. Taking into consideration the lack of the experience we had to face the challenges and quickly implement all the published data. From April 2016 till April 2023 in our center were implanted 49 CRT devices. Objective The purpose of the current article is to describe our technique of CRT implantation and the subsequent follow-up of the patients. Conclusion Cardiac resynchronization therapy is an important tool in heart failure management. The implantation could be a challenging procedure and many complications could arise. Is important to develop a proper strategy to face all the challenges.
The Effectiveness of Paternal Lymphocyte Immunotherapy for Recurrent Miscarriage in Couples with Human Leukocyte Antigen Sharing: A Novel Approach
Authors: Gunasheela Devika , Nagaraj Aparna , MV Akhila , Shetty Sachin , Shetty Swathi
Published: July 2023

Background: The aetiology of recurrent pregnancy loss (RPL) is varied and ranges from genetic abnormalities, autoimmune, uterine structural abnormalities, thrombophilic disorders, endocrinologic dysfunction, infective to idiopathic factors. Reproductive immunology may provide an area of opportunity in treatment of idiopathic cases. Research has indicated that any amount of HLA compatibility among spouses leads to immunological perturbations leading to higher RPL rates. These disturbances in alloimmune parameters are found to be significantly reduced after a successful immunotherapy with paternal lymphocytes immunotherapy (LIT) among couples who share HLA. Aim: To analyze the role of alloimmune factors in couples who are considered unexplained RPL by testing HLA sharing between the partners and to determine the effect of lymphocyte immunotherapy (LIT) on live birth rate in couples with HLA sharing. Methods: This retrospective observational study was conducted in a single tertiary center in Bangalore for a duration of three years. Couples who satisfied the inclusion and exclusion criteria were selected and HLA sharing between the partners was tested. Couples with HLA sharing received LIT before and during pregnancy. The pregnancy and live birth rates were calculated and compared with couples with HLA sharing who did not receive LIT. Results: Out of the 199 couples who were screened for HLA sharing among partners, 146 couples had different degrees of HLA sharing. 81 couples received LIT and 32 did not opt for LIT and were taken as control group. The pregnancy and live birth rates were significantly higher in the LIT group compared to control group (77.7% vs 40.6%, p-0.0001, OR 5.1, 95% CI 2.10-11.4 and 56.7% vs 21.8%, p-0.0002, OR 4.6, 95% CI 2.13-13.8 respectively). Miscarriage rates were similar between the two groups. Conclusion: Partner lymphocyte immunotherapy is a novel treatment option in improving the pregnancy outcomes among women with unexplained RPL and HLA sharing among partners.
Mortality Time Trend for Major Viral Pathogens Causing Acute Respiratory Failure in Brazilian Children and Adolescents Before and During the SARS-Cov-2 Pandemic
Authors: Kupek Emil , Mariano Tatiana
Published: July 2023

Background – Little is known about the time trend in mortality rates due to respiratory viruses other than SARS-CoV-2 and seasonal influenza among Brazilian children and adolescents. Methods – Study outcomes were mortality rates due to influenza A, influenza B, respiratory syncytial virus, metapneumovirus, rhinovirus, parainfluenza, adenovirus, and bocavirus, for age groups <5, 5-9, and 10-19 years of age, in Brazil, over the 2009-2022 period. Secondary data from the Brazilian Ministry of Health were analyzed by interval regression, bounded between reported deaths and estimated upper limit of this number, which took into account the underestimation of deaths, the error in attributing its causes in official records, and the variation due to Poisson distribution. Results - For all viruses, mortality varied little among the children under five years of age, and increased gradually among the 5-10 and 11-19-years old. The highest average mortality rates per million inhabitants over the 2009-2022 period were estimated for respiratory syncytial virus (1.04), with the lowest values for parainfluenza (0.54) and influenza B (0.55), and intermediate values in the range of 0.90 to 0.95 for influenza A, bocavirus, metapneumovirus, rhinovirus, adenovirus, and other respiratory viruses except SARS-Cov-2. Age groups of 5-9 and 10-19 years of age had similar mortality rates and were by far the largest contributors to the overall mortality rates for all viruses analyzed. Conclusion - Schoolchildren mortality due to respiratory viruses in Brazil has been rising for at least five years before the COVID-19 pandemic, and remained elevated during the pandemic. In addition to SARS-CoV-2 and seasonal influenza, respiratory syncytial virus, metapneumovirus, rhinovirus, parainfluenza, adenovirus, and bocavirus, all showed a non-ignorable impact on mortality in this age group.
Neonatal Phototherapy Adverse Effects in Infants: A Scoping Review
Authors: Mendelson Sherri
Published: July 2023

Objective: To determine what adverse effects of neonatal phototherapy have been identified and the general breadth of the research. Data Sources: A search for relevant sources was conducted using PubMed, The Cochrane Database, Ovid, and Clinical Key via EBSCO Discovery Search from January 2013-January 2023. Study Selection: Sources were included if participants had undergone phototherapy for hyperbilirubinemia during their first weeks of life, including term and preterm infants. Twenty-three sources met the inclusion criteria. Data Extraction: Extraction included citation, design, context, aim, participants, outcomes, and main results. Data Synthesis: General concepts leading the synthesis included adverse effects of neonatal phototherapy. In addition, specific subgroups of adverse effects explored included childhood allergies, childhood cancers, patent ductus arteriosus (PDA), migraine headaches, attention deficit hyperactivity disorder, autism spectrum disorder, eye disorders and acoustic disorders. Conclusion: While the quality of studies varies, more rigorous research on adverse effects of neonatal phototherapy would benefit from careful selection of methods and reference standards, direct measures of each adverse outcome identified in adults and children, and prospective cohort studies linking early neonatal exposure with each adverse outcome outcomes throughout childhood and adolescence. Elucidating the effects of hyperbilirubinemia versus neonatal phototherapy on each potential adverse outcome will help to determine if new treatment methods for infants with hyperbilirubinemia need to be developed.
The Influence of Leadership on Structural Empowerment and Work-Life Balance on Nurses’ Burnout and Patients’ Assessed Quality of Care During the Covid-19 Pandemic
Authors: Dimitrios Mihail , Maria Papatheodorou , Kloutsiniotis Panagiotis
Published: July 2023

Background: Leadership becomes crucial during major crises in which one could expect high levels of burnout and decrease in patient quality of care. The Covid-19 pandemic was a major healthcare crisis where healthcare professional and infrastructure had to cope with unprecedented levels of workload and stressful working conditions. Hence, empirical models for estimating the mitigating role of authentic leadership on nurses’ burnout during the pandemic can contribute to the utilization of best practices in managing effectively the scarce nursing personnel resources. Aims: To model the influence of leadership, through measures on structural empowerment and work-life balance, on nurses’ burnout and patients’ quality of care, and to measure the nurses΄ perception of their leadership, and the opinion of the leaders regarding their role during the Covid-19 pandemic. Methods: An institution-based cross-sectional study conducted during the third wave of the pandemic (March-July 2021). After implementing measures to enhance structural empowerment and improve work-life balance, four questionnaires referring to Authentic leadership, Structural empowerment, Work life balance, and Work Burnout were distributed to 650 nursing personnel. Moreover, 200 patients were asked to assess the received quality of care. Results: 530 valid questionnaires included in the study. Using structural equation modeling, we estimated that authentic leadership significantly influences burnout and preserves patients’ quality of care by enhancing structural empowerment and work-life balance. In assessing attitudes, leadership was rated high, 56±5 SD (max =80) by the nursing personnel. Head nurses rated their leadership significantly higher compared to the nurses, 62,13±10 SD, (p<0,001). Structural empowerment and work-life balance measures were rated 3,55±0.6 SD, and 2,67±0,5 SD, (max =5) respectively. On the burnout subscales, emotional exhaustion and cynicism rated 3,1±0,8 and 2,3±0,7 respectively, and high in professional efficacy, 2±0,5. Patients assessed their quality-of-care 3,8±0.48 SD, (4= very good and 5=excellent). Conclusion: Our study demonstrates that during major crises, leadership through structural empowerment measures and better work-life conditions mitigates nurses’ burnout and lead them to high levels of professional efficacy, thus preserving patients-quality of care. Moreover, team leaders in healthcare services should be modest and aware of their tendency to overestimate their leadership abilities.
Minimum Ganglion Cell Layer Thickness is the Best Structural Predictor of Visual Function in Leber Hereditary Optic Neuropathy
Authors: Zeng Ke , Chou Brian , Sadun Alfredo
Published: July 2023

Background: Patients with Leber hereditary optic neuropathy, a genetic cause of severe optic atrophy and blindness, demonstrate characteristic structural changes measurable through optical coherence tomography, including initial swelling of the retinal nerve fiber layer and progressive thinning of the ganglion cell layer. After symptomatic conversion, patients experience progressive vision loss, often with dense central scotomas. Aims: This study aims to explore the predictive potential of ocular structural measurements to visual function in patients with Leber hereditary optic neuropathy. Methods: Medical records were reviewed retrospectively for patients with Leber hereditary optic neuropathy clinical testing. Structural measurements, including the average thickness of the ganglion cell layer, the retinal nerve fiber layer, and minimum thickness of the ganglion cell layer, measured through optical coherence tomography were obtained along with measures of visual function such as visual acuity and mean deviation of visual field testing. Simple and multivariable linear regressions were performed to determine correlations between structural measurements and visual functions. Analyses were conducted for all patients, and subgroup of symptomatic patients. Results: Overall, 92 eyes were included with 78 symptomatic eyes. Across all patients, the minimum ganglion cell layer thickness had the highest correlation coefficient with visual acuity (Beta -0.632, adjusted R2 0.396) and with visual field function (Beta 0.572, adj. R2 0.320) compared to the average thickness of the ganglion cell layer (Beta 0.474, adj. R2 0.216) and retinal nerve fiber layer (Beta 0.481, adj. R2 0.223). In multivariate analysis, the minimum ganglion cell layer thickness was the only significant measurement that correlated with visual acuity across all eyes (Beta -0.527, P<0.001) and symptomatic eyes (Beta -0.479, P<0.001). The minimum ganglion cell layer thickness (Beta 0.440, P<0.001) and retinal nerve fiber layer average thickness (0.258, P=0.023) were significant structural measurements correlating to visual field function. Conclusion: The minimum ganglion cell layer thickness is the best structural measure predictor for visual field and visual acuity compared to other common structural measurements in patients with Leber hereditary optic neuropathy. It is a good predictor even when evaluating only symptomatic eyes. Additional attention toward the minimum ganglion cell layer thickness may offer further insight into a patient’s visual potential and the natural history of this disease.
Freeze-drying kinetics and diffusion modeling of hawthorn
Authors: HAGIG Khaled Ali , ACAR Bahadır , TAŞKESEN Edip , TAŞKESEN Edip , TAŞKESEN Edip , ÖZKAYMAK Mehmet
Published: July 2023

This study tests freeze-drying (FD) technology (Scanvac Coolsafe model, Labogene brand) to preserve hawthorn fruit. First, 100g hawthorn slices were frozen and then freeze-dried. Kinet-ic models were applied, and hawthorn’s moisture ratio and weight loss were noted after every two hours during the 14-hour freeze-drying process. Matlab program is used to perform a to-tal of eight kinetic drying models. Results show that the root mean square error was 0.011063, the highest determination coefficient was 0.9987, the least chi-square was 1.959x10-4, and the effective diffusivity was 2.33742x10-10m2/s. The diffusion approach is the best among the eight models.
A NIGHTMARE FOR TRANSPLANT PHYSICIANS: BONE MARROW DONOR CANDIDATES WITHDRAWING FROM THE DONATION PROCESS
Authors: Eker İbrahim , Düzenli Kar Yeter , Eroğlu Nilgün , Vural Özge , Avcı Kadriye , Gülgün Görkem , Aran Ali , Gül Yasin Akif , Tuğcu Ahmet Oğuz , Işık Gökçenur , Hoşgel Raşit
Published: July 2023

OBJECTIVE: Although there have been remarkable developments regarding stem-cell transplantation (HSCT) in Turkey, but the number of people who would like to be stem cell donors is not yet at the desired level. The present study aimed to assess the effect of the training delivered by specialists on the thoughts and decisions of the health employees working in our center on being HSCT donors.
MATERIAL AND METHODS: Employees in the health sector who have not received any training in HSCT were included in the study. A half-hour of collective training for all participants was delivered by the General Directorate of Health Services Turkey Stem Cell Coordination Center (TÜRKÖK) on January 11-12, 2018. The present study included 274 health employeeswho attended the training delivered by TÜRKÖK. The pre-testand post-test were applied to determine the socio-demographic characteristics of the participants, their knowledge andattitudes about stem cell transplantation before and after thetraining, and the factors that motivate and prevent them frombeing a donor.
RESULTS: Among the 95 participants, who did not think about being a donor before receiving education, the factors that caused them to not want to be a donor the most were their distrust of the health system (16.5%), the worry of causing pain (15.4%), and the thought that being a bone marrow donor had a negative impact on health (13.4%). A statistically significant increase was found in the rate of those who think about becoming a stem cell transplant donor after education (p:,0001), those who think they have enough information about stem cell transplant (p:,0001), those who think they know where to apply to be a stem cell donor (p:,000) those who thought that the society was sufficiently informed about stem cell transplantation (p:,0001). While 67.3% (171 people) of the participants stated that their determination to be a donor would continue until the end of the whole process, 32.7% (83 people) stated that they could stop being a donor.
CONCLUSIONS: Our results show that continuing giving such trainings, especially in institutions, will contribute to the increase of the number of stem cell donor volunteers to a sufficient level by raising awareness on the subject and reducing false beliefs in our country.
LEVELS OF CYBERCHONDRIA, HEALTH ANXIETY AND INTERNET ADDICTION IN MEDICAL FACULTY STUDENTS
Authors: Çalhan Semih , Erdoğan Ali
Published: July 2023

OBJECTIVE: In this study, it was aimed to compare the levels of cyberchondria, health anxiety and internet addiction of medical faculty students with other faculty students. MATERIAL AND METHODS: 223 students studying at the faculty of medicine and 211 students studying at other faculties were included in the study. Students studying in health-related faculties such as nursing etc. were not included in the study. Socio-demographic data form, Cyberchondria Severity Scale (CSS), Health Anxiety Inventory (HAI), and Young Internet Addiction Scale (YIAS) were administered to all participants. RESULTS: The mean age of medical faculty students (21.27±2.27 years) was found to be similar to the mean age of other faculty students (21.38±2.05 years) (p=0.440). HAI mean scores were found to be significantly higher in medical faculty students than in other faculties (p=0.007). YIAS and CSS scores were found to be similar in both groups (respectively; p=0.536, p=0.960). YIAS scores and CSS scores of medical faculty students in pre-clinical classes were higher than those in clinical classes (respectively; p=0.017, p<0.001). As the age increased in all participants, the YIAS scores decreased (r= -0.119, p=0.013). CONCLUSIONS: It can be said that health anxiety is higher in medical faculty students. In addition, cyberchondria levels and internet addiction levels are higher in medical school students in pre-clinical classes than in clinical classes. We suggest that the awareness levels of students about health anxiety and cyberchondria should be increased in medical school education, where the knowledge about diseases increases intensively.
POST-MORTEM INTERVAL ESTIMATION BASED ON LIVER AND STRIATED MUSCLE COMPUTED TOMOGRAPHY ATTENUATIONS IN RATS
Authors: Yıldırım Mahmut Şerif , Tümer Ali Rıza , Akçan Ramazan , Omay Burak , Akata Deniz , Onbaşılar İlyas
Published: July 2023

OBJECTIVE: The interest on post-mortem computed tomographic studies targeting post-mortem interval (PMI) estimations is increasing. Most studies have been conducted in an uncontrolled or relatively less controlled condition. However, this study investigates the usefulness of computed tomography attenuations of the liver and striated muscles in PMI estimation under strictly controlled environmental conditions.
MATERIAL AND METHODS: Post-mortem computed tomography images of 30 Wistar Albino rats were obtained in the first 30 min after death and 12, 24, 36, 48, 72, 96, 120, 144 and 168-hours following death. Repeated attenuations of both thelateral lobes of the liver and paraspinal muscle were recorded in 0.12-cm2 regions of interest.
RESULTS: The attenuation values of the liver and paraspinal muscles were higher 12-hour post-mortem. A significant difference was observed between the images obtained 30 minutes post-mortem and those obtained 12 hours post-mortem in both male (p=0.01) and female rats (p=0.01). Different cut-off attenuation values for the liver and muscle tissue were determined to estimate the post-mortem interval.
CONCLUSIONS: The use of attenuation values of the liver and striated muscles with the proposed model was found to be beneficial for the determination of PMI. The cut-off values of attenuation, especially for the liver, can be used in the delimitation of the post-mortem interval.
MODERN EĞİTİMDEKİ YENİLİKÇİ YAKLAŞIMLAR ÇERÇEVESİNDE ANATOMİ DERSİNİN ÖĞRENCİ BAKIŞ AÇISIYLA DEĞERLENDİRİLMESİ
Authors: Demir Mehmet , Ateşoğlu Karabaş Sibel , Arpacı Muhammed Furkan , Doğaner Adem , Yoldaş Atila
Published: July 2023

AMAÇ: Son 30 yılda tıp fakültelerinin eğitim öğretim programlarında görülen müfredat değişikliklerine rağmen anatomi eğitimi temel bir disiplin olarak önemini korumuştur. Bu çalışmanın amacı Kahramanmaraş Sütçü imam Üniversitesi Tıp Fakültesi’ndeki anatomi eğitiminin mevcut durumunun ve eğitim-öğretim sürecine ilişkin sorunların öğrencilerin geribildirimleri ışığında belirlenmesidir.
GEREÇ VE YÖNTEM: Çalışmamıza 2021 - 2022 Eğitim–Öğretim yılında Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesinde eğitim gören 482 gönüllü katıldı. Çalışmada Dönem I’ den 167 (% 94,35), Dönem II’ den 151 (%88,30) ve Dönem III ‘den ise 164 (%89,13) öğrenci bulunmaktadır. Tüm öğrencilere gönüllük esasına uygun olarak anatomi eğitimiyle ilgili Google Forms üzerinden 17 soruluk bir anket uygulandı (Teorik eğitimle ilgili 6, İnternetle ilgili 2, Sınavlarla ilgili 4 ve Pratik eğitimle ilgili 5 soru).
BULGULAR: Tıp Fakültesi öğrencilerinin %96,9‘u anatomi dersinin iyi bir hekim olmak için mutlaka gerekli olduğunu belirtti. Sunumların ve maketlerin Anatomi eğitiminin teorik kısmının anlaşılmasını kolaylaştırdığını ifade edenlerin oranı sırasıyla %88,4 ve %97,7’dir. Öğrencilerin % 87,82'si öğretim elemanlarının ders panosunun son dersinde vaka raporlarının tartışılmasını önerdi. Almayı planladığımız 3D (üç boyutlu) interaktif anatomi programları hakkında öğrencilerin %78,4'ü olumlu görüş bildirdi. Öğrencilerin %92,1’i laboratuvar derslerinin yararlı olduğunu, %89’u laboratuvarın daha iyi organize edilmesi gerektiğini ve %78,4’ü kadavra diseksiyonun önemli olduğunu belirtti.
SONUÇ: Tıp fakültesi öğrencilerinin geri bildirim sonuçları anatomi eğitimiyle ilgili yeni eğitim metodolojisin geliştirilmesinde, mevcut eksikliklerin giderilmesinde yararlı olacağını düşünmekteyiz.
Современные подходы к построению архитектуры масштабируемых веб-сервисов
Authors: Богомолов . Р.Д
Published: July 2023

На сегодняшний день веб-сервисы являются предпочтительным способом представления информационных систем за счѐт своей мультиплатформенности и гибкости. Подобные системы становятся всѐ масштабнее и сложнее по своему внутреннему устройству. Для обеспечения развития и поддержки таких систем необходимо придавать им свойство к масштабированию. Такое свойство может обеспечить грамотно спроектированная архитектура информационной системы. В статье рассмотрены основные подходы к современному построению архитектуры масштабируемых веб-сервисов
Анализ применения методов многокритериальной оптимизации на этапе выбора стратегии проектирования корпоративных информационных систем
Authors: Борзых Н.Ю., , Смоленцева Т.Е.
Published: July 2023

В работе проведен анализ методов многокритериальной оптимизации. Рассмотрен пример формирования критериев на этапе выбора стратегии проектирования корпоративных информационных систем (КИС). Сформулированы основные вопросы по рассмотренным методам с предложениями о возможности корректировки входного набора критериев при выборе стратегии проектирования КИС
Виртуализация вычислительных машин и центры обработки данных в вычислительных сетях
Authors: Данилин Д.Д , Мартышкин А.И , Данилов Е.А.
Published: July 2023

В данной статье будут рассмотрены различные подходы к виртуализации и центрам обработки данных, а также преимущества и недостатки каждого из них. Будут рассмотрены такие темы, как виртуализация на уровне операционной системы, гипервизоры, контейнеризация и другие технологии. Также будут рассмотрены различные аспекты управления центрами обработки данных, такие как масштабирование, мониторинг и безопасность. Наконец, мы рассмотрим некоторые из наиболее популярных продуктов и решений, которые используются для виртуализации и управления центрами обработки данных.
Моделирование однородных сетей с использованием механизма тройственного замыкания
Authors: Ступак А.В. , Сагаева И.Д
Published: July 2023

В статье описывается алгоритм построения искусственной сети и сравниваются характеристики реальной сети и искусственной сети, построенной с помощью механизма тройственного замыкания.
Безопасность облачных технологий при использовании СЭД
Authors: Шапорова Е..М , Яйлаханян А.А.
Published: July 2023

В данной статье анализируется значение и сущность облачных технологий, а также раскрываются особенности, достоинства и недостатки их применения компаниями, которые стремительно развивают электронный документооборот. Облачные технологии воздействуют на процесс документационного обеспечения управления, и позволяют упростить решение многих задач, прибегая к использованию современных информационных систем и технологий.
Способы совершения мошенничества с использованием ложных данных граждан
Authors: Хабибрахманова А.И. , Галяутдинов Р.Р.
Published: July 2023

Научно-технический прогресс и модернизация нашего общества вызвали не только рост мошенничества, но и появление новых способов, изучение которых является важным для расследования преступления. В данной статье рассматриваются основные способы совершения мошенничества с использованием ложных данных граждан, в том числе способы совершения мошенничества с использование информационных технологий при получении неправомерного доступа к личным данным граждан, а также анализируется судебная практика и рассматривается проблема необходимости разграничения кражи и мошенничества
Философия в проблемах медицины XXI века
Authors: Векессер В.С.
Published: July 2023

Философия является неотъемлемой частью медицины. В данной статье рассмотрены роль философии в аспекте современной медицины, а также её применение в практике медицинского работника.
Состояние лесных дач металлургических заводов Вятской губернии в дореформенный период
Authors: Васина Т.А.
Published: July 2023

В статье на основе архивных документов и законодательных актов характеризуется лесное хозяйство горнозаводских округов Вятской губернии в конце XVIII – первой половине XIX в. Уделяется внимание становлению системы государственного управления лесами, в том числе в горном ведомстве. Анализируется структура заводских лесных дач, ее динамика на протяжении изучаемого периода.
Операция «Милосердие» – деятельность комсомольских организаций Смоленской области в конце 1980-х гг
Authors: Иванова М.В. , Ермачкова А.П.
Published: July 2023

В статье описывается деятельность комсомольских организаций по оказании шефской помощи домам-интернатам Смоленской области. Авторы работы на примере операция «Милосердие» показывают различные формы и виды поддержки ветеранам и одиноким престарелым студентами средних и высших учебных заведений. Делается вывод, что из-за начавшейся перестройки и коммерциализации комсомола, партийные комитеты пытались перестроить работу, но за партийными реорганизациями у них мало оставалось времени для работы с молодежью и подшефными организациями, что, в конечном счете, привело ВЛКСМ к самороспуску.
«Коммунистическое отношение к труду» как часть вопроса о повседневности
Authors: Новинская Т.Ю
Published: July 2023

В статье анализируется связь между социалистическим соревнованием, как «закономерностью развития творческой активности» масс, и объективными и субъективными условиями сельской повседневности.
Цивилизация как сложный и многозначный феномен
Authors: Стамова Р.Д. , Гаппасова А.Г.
Published: July 2023

В статье рассматриваются различные понимания и оценки такого сложного и противоречивого феномена, как цивилизация.
Инклюзивный туризм и пути решения данной проблемы на рынке средств размещений республики Дагестан
Authors: Абачараева Х.А.
Published: July 2023

В статье приводится анализ современного состояния развития инклюзивного туризма на рынке средств размещений. Рассмотрены пути решения данной проблемы и перспективы развития инклюзивного туризма на территории республики Дагестан.
Проблемы и направления повышения эффективности предприятия
Authors: Газиева Л.Р
Published: July 2023

В данной статье рассматривается проблема повышения эффективности корпоративной финансово-хозяйственной деятельности. Определено, что основным вопросом повышения эффективности бизнеса является обеспечение максимально возможной отдачи от каждой единицы затраченного труда, материальных и финансовых ресурсов. Рассмотрены основные направления повышения эффективности хозяйственно-финансовой деятельности предприятий.
Аналитическое обоснование инвестиционной политики организации: задачи, факторы формирования, способы оценки ее экономических и финансовых последствий
Authors: Евдокимова Е.Н
Published: July 2023

Для развития любой организации необходим капитал от внешних источников. Многие компании сегодня заинтересованы в привлечении инвестиций, и им приходится доказывать свою инвестиционную привлекательность. Увеличение инвестиционной привлекательности компании позволяет ей успешно развиваться, наращивать обороты и расширять деятельность, а также продолжать вести деятельность в условиях огромной конкуренции. Таким образом, инвестиционная политика во многом определяет перспективы развития предприятия.
Совершенствование организации кинологической службы ФТС России
Authors: Евтюхова У.С. , Гранатырь А.И. , Буряков А.С.
Published: July 2023

Данная работа заключается в анализе отрасли кинологии, относящейся к таможенным органам и способам расширения сфер ее применения. Востребованность в проведении анализа обусловлена наличием актуальных проблем в сферах деятельности таможенных органов, где применение кинологической отрасли отсутствует, необходимо или может значительно облегчить работу, из-за чего есть потребность в проведение мероприятий по максимальному внедрению данной службы таможенные органы. В рамках статьи рассмотрены теоретические аспекты понятия «кинологическая служба». Проанализированы тенденции борьбы с контрабандой и другими нарушениями таможенного законодательства при помощи использования кинологической службы России. Предложены основные направления совершенствования деятельности таможенных органов с помощью использования рассматриваемой службы.
Привлечение работающего населения к занятиям физической культурой и спортом
Authors: Першина С.В. , Пиунова М.А.
Published: July 2023

В статье подчеркивается важность привлечения населением к занятиям оздоровительной направленности. Рассмотрены аналитические материалы выполнения муниципальной Программы «Физическая культура – Здоровье - Спорт» на примере муниципального образования города Новый Уренгой. Разработаны и представлены мероприятия, позволяющие повысить интерес работающего населения муниципального образования города Новый Уренгой к занятиям физической культурой и спортом средствами спортивных мероприятий.
Сущность анализа и оценки реализации государственных программ
Authors: Пронин В.В. , Родина Е.Е.
Published: July 2023

В современном мире важнейшей задачей является устойчивое экономическое развитие, которую ставит перед собой каждое государство. В целях повышения результативности от управления государственными расходами в системе государственного управления выбран наиболее эффективный инструмент – программно-целевое управление и планирование в рамках государственных программ.
Внутренние и внешние экономические и политические причины разработки Китайской Народной Республикой проекта «Один пояс, один путь»
Authors: Юдаев А.С
Published: July 2023

На сегодняшний день проект «Один пояс – один путь» – это важнейший и масштабный проект, отвечающий возросшим экономическим возможностям данной страны. Китай – это мировой экономический лидер в сфере материального производства. Таким образом, если по уровню ВВП, в который в современной экономике значительный вклад вносит сфера услуг, сильно зависящая от уровня оплаты труда в каждой стране, КНР еще экономика номер два в мире, то по уровню материального производства, где роль этого фактора меньше, она уже первая. Так, можно говорить, что Китай нуждается в новых направлениях развития, то есть помимо ориентации на внутренний рынок необходимо увеличение экспорта в другие страны и инвестиции за рубеж. Таким образом, представленная инициатива «Один пояс, один путь» в 2013 году Си Цзиньпином безусловно отвечает интересам китайском экономики.
Проблема самоотношения одаренных детей в отечественной и зарубежной психологической литературе
Authors: Комиссарова Д.В. , Капичникова О.Б
Published: July 2023

В данной статье представлен теоретический обзор по проблеме самоотношения одаренных детей. Самоотношение рассматривается как один из компонентов самосознания личности. Отмечается специфика характера самоотношения одаренных детей и его взаимосвязь с самооценкой личности. В статье затронуто феномен одаренности и то, что у одаренных детей наблюдаются высокие показатели самоуважения, самообвинения, самопонимания, а на бессознательном отмечаются низкие показатели принятия собственной личности. Отмечено, что для формирования адекватной самооценки одаренного ребенка действенно сотрудничество взрослых и детей, что приведет к продуктивной деятельности, созданию благоприятных условий для развития личностных качеств, позволяющих эффективно и успешно действовать в будущем.
Современное отношение корейской молодежи к семье и браку
Authors: Кобякова В.В. , Егорова К.Г
Published: July 2023

В данной статье на основе статистических данных, результатов исследований, рассматривается представление и отношение корейской молодежи к семье и браку. В данной работе мы попытаемся ответить на вопрос: придерживаются ли молодые люди традиционной концепции семьи?
Формирование опыта познавательной инициативы и самостоятельности старших дошкольников в процессе опытно-экспериментальной деятельности
Authors: Самойлова В.С , Сычёва М.В
Published: July 2023

В статье рассматривается проблема формирования познавательной инициативы и самостоятельности старших дошкольников. Основное внимание уделено тому, что именно системная опытно-экспериментальная деятельность поможет решить данную проблему.