bluuebunny/crossref_metadata_2025 huggingface dataset:
Collecting the Public Perception of AI and Robot Rights
Authors: Lima Gabriel , Kim Changyeon , Ryu Seungho , Jeon Chihyung , Cha Meeyoung
Published: October 2020

Whether to give rights to artificial intelligence (AI) and robots has been a sensitive topic since the European Parliament proposed advanced robots could be granted "electronic personalities." Numerous scholars who favor or disfavor its feasibility have participated in the debate. This paper presents an experiment (N=1270) that 1) collects online users' first impressions of 11 possible rights that could be granted to autonomous electronic agents of the future and 2) examines whether debunking common misconceptions on the proposal modifies one's stance toward the issue. The results indicate that even though online users mainly disfavor AI and robot rights, they are supportive of protecting electronic agents from cruelty (i.e., favor the right against cruel treatment). Furthermore, people's perceptions became more positive when given information about rights-bearing non-human entities or myth-refuting statements. The style used to introduce AI and robot rights significantly affected how the participants perceived the proposal, similar to the way metaphors function in creating laws. For robustness, we repeated the experiment over a more representative sample of U.S. residents (N=164) and found that perceptions gathered from online users and those by the general population are similar.
'Yes, I comply!'
Authors: Feger Sebastian S. , Wozniak Paweł W. , Lischke Lars , Schmidt Albrecht
Published: October 2020

As science becomes increasingly data-intensive, the requirements for comprehensive Research Data Management (RDM) grow. This often overwhelms scientists, requiring more workload and training. The failure to conduct effective RDM leads to producing research artefacts that cannot be reproduced or reused. Past research placed high value on supporting data science workers, but focused mainly on data production, collection, processing, and sensemaking. In order to understand practices and needs of data science workers in relation to documentation, preservation, sharing, and reuse, we conducted a cross-domain study with 15 scientists and data managers from diverse scientific domains. We identified five core concepts which describe requirements, drivers, and boundaries in the development of commitment for RDM, essential for generating reproducible research artefacts: Practice, Adoption, Barriers, Education, and Impact. Based on those concepts, we introduce a stage-based model of personal RDM commitment evolution. The model can be used to drive the design of future systems that support a transition to open science. We discuss infrastructure, policies, and motivations involved at the stages and transitions in the model. Our work supports designers in understanding the constraints and challenges involved in designing for reproducibility in an age of data-driven science.
What Happens to All These Hackathon Projects?
Authors: Nolte Alexander , Chounta Irene-Angelica , Herbsleb James D.
Published: October 2020

Time-based events, such as hackathons and codefests, have become a global phenomenon attracting thousands of participants to hundreds of events every year. While research on hackathons has grown considerably, there is still limited insight into what happens to hackathon projects after the event itself has ended. While case studies have provided rich descriptions of hackathons and their aftermath, we add to this literature a large-scale quantitative study of continuation across hackathons in a variety of domains. Our findings indicate that a considerable number of projects get continued after a hackathon has ended. Our results also suggest that short- and long-term continuation are different phenomena. While short-term continuation is associated with technical preparation, number of technologies used in a project and winning a hackathon, long-term continuation is predicated on skill diversity among team members, their technical capabilities in relationship to the technologies and their intention to expand the reach of a project. Moreover, we found intensive short-term activity to be associated with a lower likelihood of long-term project continuation.
Data and Power
Authors: Schoenebeck Sarita , Conway Paul
Published: October 2020

Digital data pervades everyday life, from personal photos shared on social media to voice commands for Amazon Alexa. A widespread industry culture of 'move fast and break things,' however, has compelled data management practices that prioritize profit over preservation. This paper draws from archival theories of appraisal to foreground control, power, subjectivity, and emotion in computing practices that treat data storage as a neutral or objective cost-center. We draw on postmodern archival appraisal theory that recognizes the archive as a powerful and subjective curator of identity and memory. The theoretical basis of archival decision practices, in turn, establishes the value of the archival record and thus the need to save it. With three primary issues of appraisal theory as a framework, we report on an interview study with adults (N=17), ages 51-72, who are in a transitional life-stage that focuses them on their experiences and memories that are worth keeping or discarding. We sketch implications for data management paths that forefront legacy, life transitions, precarity, and control.
"At the End of the Day Facebook Does What ItWants"
Authors: Vaccaro Kristen , Sandvig Christian , Karahalios Karrie
Published: October 2020

Interest has grown in designing algorithmic decision making systems for contestability. In this work, we study how users experience contesting unfavorable social media content moderation decisions. A large-scale online experiment tests whether different forms of appeals can improve users' experiences of automated decision making. We study the impact on users' perceptions of the Fairness, Accountability, and Trustworthiness of algorithmic decisions, as well as their feelings of Control (FACT). Surprisingly, we find that none of the appeal designs improve FACT perceptions compared to a no appeal baseline. We qualitatively analyze how users write appeals, and find that they contest the decision itself, but also more fundamental issues like the goal of moderating content, the idea of automation, and the inconsistency of the system as a whole. We conclude with suggestions for -- as well as a discussion of the challenges of -- designing for contestability.
Rare, but Valuable: Understanding Data-centered Talk in News Website Comment Sections
Authors: McInnis Brian James , Sun Lu , Shin Jungwon , Dow Steven P.
Published: October 2020

News websites can facilitate global discussions about civic issues, but the financial cost and burden of moderating these forums has forced many to disable their commenting systems. In this paper, we consider the role that data visualizations play in online discussion around a civic issue, through an analysis of how people talk about climate change data in the comment threads at three news websites (i.e., Breitbart news, the Guardian, the New York Times). We find that out of 6,525 comments, only 2.4% reference data visualizations in the articles. While rare, the paper presents illustrative examples of how people refer to data---their collection, analysis, and visual representation---to engage with an article's narrative. Using text classification techniques we identify several features related to the content of comments that contain data-centered talk, such as article cosine similarity, hyperlinks, and comparison terms. Finally, we discuss potential ways that newsrooms might apply this analysis to promote data literacy, data science, and to foster community around shared experiences.
A Taxonomy of Team-Assembly Systems
Authors: Gómez-Zará Diego , DeChurch Leslie A. , Contractor Noshir S.
Published: October 2020

The emergence of team-assembly technologies has brought with it new challenges in designing and implementing socio-technical systems. Our understanding of how systems shape the team-assembly processes is still limited. How do systems enable users to find teammates? How do users make decisions when using these systems? And what factors explain the characteristics of the teams assembled? Building on existing literature from CSCW, computer science, and management science, we propose a taxonomy to characterize how systems influence team assembly. This taxonomy argues that two dimensions determine how systems shape team assembly: (i) users? agency, to what extent the system enables its users to exercise their agency, and (ii) users? participation, how many users the system allows to participate in the team-formation process. The intersection of these two dimensions manifest four types of teams enabled by systems: self-assembled teams, staffed teams, optimized teams, and augmented teams. We characterize each one of these types of teams, considering their qualities, advantages, and challenges. To contextualize these types of teams, we map the current literature of team-assembly systems using a scoping literature review. Lastly, we discuss ways through which these two dimensions alter users' behavior, team diversity, and team composition. This paper provides theoretical implications and research questions for future systems that reconfigure the organization of people into teams.
An Intelligent Edge-centric Queries Allocation Scheme based on Ensemble Models
Authors: Kolomvatsos Kostas , Anagnostopoulos Christos
Published: October 2020

The combination of Internet of Things (IoT) and Edge Computing (EC) can assist in the delivery of novel applications that will facilitate end-users’ activities. Data collected by numerous devices present in the IoT infrastructure can be hosted into a set of EC nodes becoming the subject of processing tasks for the provision of analytics. Analytics are derived as the result of various queries defined by end-users or applications. Such queries can be executed in the available EC nodes to limit the latency in the provision of responses. In this article, we propose a meta-ensemble learning scheme that supports the decision making for the allocation of queries to the appropriate EC nodes. Our learning model decides over queries’ and nodes’ characteristics. We provide the description of a matching process between queries and nodes after concluding the contextual information for each envisioned characteristic adopted in our meta-ensemble scheme. We rely on widely known ensemble models, combine them, and offer an additional processing layer to increase the performance. The aim is to result a subset of EC nodes that will host each incoming query. Apart from the description of the proposed model, we report on its evaluation and the corresponding results. Through a large set of experiments and a numerical analysis, we aim at revealing the pros and cons of the proposed scheme.
Space-Time Evolution of Subway Vulnerability Based on Hypergraph Space
Authors: Lu Kaihua , Gu Xiaoyan
Published: October 2020

How to qualitatively and quantitatively evaluate the ability of the whole subway system to maintain the maximum normal operation has become a noteworthy topic. In this study, the hypergraph space structure of Nanjing subway network is used for research. This study uses the method of time-space evolution mechanism to dynamically and quantitatively analyze the gradual change characteristics of Nanjing subway system vulnerability under the influence of time and space. In addition, this study also makes static and dynamic comparative analysis on the vulnerability of a subway system by using connectivity rate and trip efficiency index, which provides new analysis methods and ideas for the study of a subway system network. The results show that although the overall structure of Nanjing’s subway network shows a loose trend, as Nanjing’s subway is still in a rapid development stage, it can be seen from the long-term planning of Nanjing’s subway that the construction of Nanjing’s subway ring line will be strengthened after the completion of the connection between the main city and the suburbs. Therefore, the vulnerability of the subway system should be reduced and the reliability will be improved.
Numerical Modelling of Clay Seal Maturation in Deep Boreholes with Nuclear Waste
Authors: Yang Ting , Mattsson Hans , Pusch Roland , Laue Jan , Knutsson Sven , Liu Xiaodong
Published: October 2020

One of the major challenges of high‐level nuclear waste (HLW) isolation in deep boreholes is to anticipate the maturation behaviour of swelling clay when the waste, surrounded by dense clay encased in perforated tubes, is submerged into the borehole mud. The ultimate homogeneity of this clay seal acting as a barrier is expected to stabilize the borehole and to prevent possible leakage of radioactivity. In this study, a numerical model for predicting the maturation of the clay barrier has been developed. In the model, the water transport is controlled by the differences in the suction potential and the permeability. The model is able to simulate the maturation process, both the expeditious water transport and the clay migration into the surrounding mud, from beginning to end. Results from laboratory tests of the clay maturation were compared with the predictions made by the model. They are in good agreement, but refinement is proposed by taking the impact of the tube perforation on the maturation rate into more consideration. The proposed numerical model will also be useful in selecting a suitable design for clay barriers in HLW boreholes. Different combinations of clay dimensions and initial densities of mud and dense clay can thus be studied to determine the final homogenization and the end densities.
The Slow Spinning Motion of a Rigid Body in Newtonian Field and External Torque
Authors: Ismail A. I.
Published: October 2020

In this paper, the problem of the slow spinning motion of a rigid body about a point O, being fixed in space, in the presence of the Newtonian force field and external torque is considered. We achieve the slow spin by giving the body slow rotation with a sufficiently small angular velocity component

r

0

about the moving z-axis. We obtain the periodic solutions in a new domain of the angular velocity vector component

r

0

⟶
0

, define a large parameter proportional to

1
/

r

0

, and use the technique of the large parameter for solving this problem. Geometric interpretations of motions will be illustrated. Comparison of the results with the previous works is considered. A discussion of obtained solutions and results is presented.
Negative Effects of SIGIRR on TRAF6 Ubiquitination in Acute Lung Injury In Vitro
Authors: Tian Feng , Lu Qiang , Lei Jie , Ni Yunfeng , Xie Nianlin , Zhong Daixing , Yang Guang , Si Shaokui , Jiang Tao
Published: October 2020

In this study, the effects of single immunoglobin IL-1 receptor-related protein (SIGIRR) on tumor necrosis factor- (TNF-) receptor-associated factor 6 (TRAF6) ubiquitination in acute lung injury (ALI) were evaluated in both alveolar epithelial cells and alveolar macrophage cells in vitro. Our results found that SIGIRR negatively regulated TRAF6 ubiquitination and such SIGIRR inhibition could enhance the TRAF6 expression in both alveolar epithelial cells (AECs) and alveolar macrophage cells (AMCs). SIGIRR knockdown may increase NF-κB activity via TRAF6 regulation by the classical but not the nonclassical NF-κB signaling pathway. Such modulation between TRAF6 and SIGIRR could affect cytokine secretion and exacerbate the immune response; the IL-8, NFKB1, and NFKBIA mRNA levels were reduced after SIGIRR overexpression. The current study reveals the molecular mechanisms of the negative regulatory roles of SIGIRR on the innate immune response related to the LPS/TLR-4 signaling pathway and provides evidence for strategies to clinically treat inflammatory diseases.
Study on the Model Test of the Antibreaking Effect of Fiber Reinforced Concrete Lining in Tunnel
Authors: Cui Guang-yao , Wang Xue-lai , Wang Dao-yuan
Published: October 2020

In order to study the antibreaking effect of the fiber reinforced concrete lining in the tunnel, this paper takes the a subway tunnel engineering project in F2-3 section of Jiujiawan fault as the research background and carries out the antibreaking model test of the fiber reinforced concrete lining in the active fault zone of high earthquake intensity. The results show that the antibreaking effect of the principle stress and the longitudinal strain of the fiber reinforced concrete lining are 30%∼40% and 80%∼90%, respectively, and the minimum value of the structural safety factor is increased by 4∼5 times. The antibreaking effect of hybrid fiber reinforced concrete lining is better than that of steel fiber reinforced concrete lining. The safety of steel polypropylene hybrid fiber reinforced concrete tunnel lining is the highest, and its minimum structural safety factor is 1.62. In the aspect of improving the antibreaking effect of the tunnel, the toughening effect of fiber reinforced concrete is stronger than that of reinforcing. The research results are of great significance to improve the antibreaking effect of tunnels in active fault areas with high earthquake intensity.
The Analysis of the Transformation Mechanism of cBN Crystals with the First-Principle Calculation
Authors: Cai Lichao , Xu Bin , Lv Meizhe , Fan Xiaohong
Published: October 2020

To clarify the synthesis mechanism of cubic boron nitride (cBN) with catalysts at high temperature and high pressure, we calculate the surface energy of the main phases in the Li-N-B synthesis system using the first-principle method. Based on the density functional theory, the surface energy of low-index surfaces of cBN, hexagonal boron nitride (hBN), and lithium boron nitride (Li3BN2) at the cBN synthetic temperature of 1700 K and synthetic pressure of 5.0 GPa is calculated. The surface energy of the main low-index surfaces of cBN is σ (111) > σ (001) > σ (110), that of hBN is σ

10

1
¯

0

 > σ

11

2
¯

0

 > σ (0001), and that of Li3BN2 is σ (100) > σ (110) > σ (001). The energy orders of the main low-index surfaces were well contrary to the corresponding orders of the valence electron density of the low-index surfaces of cBN, hBN, and Li3BN2, which were calculated by the empirical electron theory (EET) of solids and molecules. The result shows that the calculation results in this paper are well consistent with the previous results of the EET theory and support for the results of the “direct transformation of hBN to cBN under the catalysis of Li3BN2” obtained by the EET theory.
Development of Hepatocellular Carcinoma in a Patient with Chronic Hepatitis C 21 Years after Achieving a Sustained Virological Response to Interferon Therapy
Authors: Hara Tasuku , Ohara Tomoya , Taniguchi Masashi , Sakai Toshiaki , Oka Kohei , Iwai Naoto , Tsuji Toshifumi , Okuda Takashi , Komaki Toshiyuki , Sakagami Junichi , Kagawa Keizo
Published: October 2020

A 77-year-old man with chronic hepatitis C (CH-C) infection, who achieved a sustained virological response (SVR) to interferon (IFN) therapy, was followed up regularly. Before IFN therapy, he did not have metabolic diseases, and the histological diagnosis of his chronic hepatitis was stage-3 fibrosis. After achieving SVR, the fibrosis-4 (FIB-4) index level dropped once but gradually increased. 21 years after SVR, hepatocellular carcinoma (HCC) was diagnosed by dynamic computed tomography. The HCC was 12 mm in diameter. The HCC was treated with radiofrequency ablation. CH-C patients with advanced fibrosis require long-term follow-up, even after achieving SVR.
Multiobjective Optimization of Cloud Manufacturing Service Composition with Improved Particle Swarm Optimization Algorithm
Authors: Li Yongxiang , Yao Xifan , Liu Min
Published: October 2020

Aiming at the problems of low search efficiency and inaccurate optimization of existing service composition optimization methods, a new multiobjective optimization model of cloud manufacturing service composition was constructed, which took service matching degree, composition synergy degree, cloud entropy, execution time, and execution cost as optimization objectives, and an improved particle swarm optimization algorithm (IPSOA) was proposed. In the IPSOA, the integer encoding method was used for particle encoding. The inertia coefficient and two acceleration coefficients were improved by introducing the normal cloud model, sine function, and cosine function. The global search ability of IPSOA in the early stage was improved, and its prematurity was restrained to form a more comprehensive solution space. In the later stage, IPSOA focused on the local fine search and improved the optimization precision. Taking automatic guided forklift manufacturing task as an example, the correctness of the proposed multiobjective optimization model of cloud manufacturing service composition and the effectiveness of its solution algorithm were verified. The performance of IPSOA was analyzed and compared with standard genetic algorithm (SGA) and traditional particle swarm optimization (PSO). Under the same conditions, IPSOA had a faster convergence speed than PSO and SGA and had better performance than PSO.
Ultrawideband Harmonic Suppression in Microstrip Patch Antenna Using Novel Defected Ground Structures
Authors: Fan Jun , Lin Jiangchuan , Qin Feng , Cai Jinliang , Kan Mingxu
Published: October 2020

Suppressing higher-order modes up to sixth harmonics of the fundamental working frequency in a single-layer microstrip line-fed patch antenna has been successfully demonstrated. Higher-order modes of the antenna are suppressed by simultaneously employing a circular head open stub connected to the feed line and a novel defected ground structure (DGS) beneath the feed line. The filtering property of the antenna has been improved by the novel DGS significantly. The role played by the novel DGS is carefully analyzed, and the effect of some key parameters of DGS is further discussed. A microstrip patch antenna with the working frequency 3.13 GHz (fc) is designed and manufactured. The designed antenna possesses an ultrawideband harmonic suppression capability ranging from 2fc to 6fc. More importantly, the area occupied by the novel DGS is decreased by 41% compared to the earlier design.
RT-qPCR versus Digital PCR: How Do They Impact Differently on Clinical Management of Chronic Myeloid Leukemia Patients?
Authors: Zanaglio Camilla , Bernardi Simona , Gandolfi Lisa , Farina Mirko , Re Federica , Polverelli Nicola , Zollner Tatiana , Turra Alessandro , Morello Enrico , Malagola Michele , Russo Domenico
Published: October 2020

Real-time quantitative PCR (RT-qPCR) is the gold standard to quantify the BCR-ABL1 transcript for molecular response monitoring in chronic myeloid leukemia (CML) patients, and it plays a pivotal role in clinical decision-making process, even if it presents technical limits. Increasing data suggest that digital PCR (dPCR) is more accurate and reliable than RT-qPCR in CML minimal residual disease monitoring and in patients’ selection for treatment discontinuation. But what about the identification of treatment discontinuation failures? We present the case of a CML patient enrolled both in a study aiming to comparatively assess molecular response by RT-qPCR and dPCR and in the progressive arm of the OPTkIMA trial. This is a phase III trial including CML patients randomized to receive a fixed versus a progressive intermittent tyrosine kinase inhibitor regimen. At 24 months, because of two consecutive detections of MR2.0 by RT-qPCR, the patient resumed daily treatment. Conversely, dPCR revealed a stability of molecular response and even a slight decreasing of transcript over time. An additional specimen was sampled one month after the first MR2.0 detection because of clinical decision: RT-qPCR resulted MR3.0 and dPCR confirmed the transcript’s stability. Nowadays, the resumption of therapy is RT-qPCR-driven despite its limits in detection and robustness. In this case, according to dPCR, the patient could have continued intermittent treatment and the stability of response was then confirmed by RT-qPCR. So, dPCR could be able to better identify peculiar clinical response to therapy.
Endothelial HMGB1 Is a Critical Regulator of LDL Transcytosis via an SREBP2–SR-BI Axis
Authors: Ghaffari Siavash , Jang Erika , Naderinabi Farnoosh , Sanwal Rajiv , Khosraviani Negar , Wang Changsen , Steinberg Benjamin E. , Goldenberg Neil M. , Ikeda Jiro , Lee Warren L.
Published: October 2020

Objective:

LDL (low-density lipoprotein) transcytosis across the endothelium is performed by the SR-BI (scavenger receptor class B type 1) receptor and contributes to atherosclerosis. HMGB1 (high mobility group box 1) is a structural protein in the nucleus that is released by cells during inflammation; extracellular HMGB1 has been implicated in advanced disease. Whether intracellular HMGB1 regulates LDL transcytosis through its nuclear functions is unknown.

Approach and Results:

HMGB1 was depleted by siRNA in human coronary artery endothelial cells, and transcytosis of LDL was measured by total internal reflection fluorescence microscopy. Knockdown of HMGB1 attenuated LDL transcytosis without affecting albumin transcytosis. Loss of HMGB1 resulted in reduction in SR-BI levels and depletion of SREBP2 (sterol regulatory element-binding protein 2)—a transcription factor upstream of SR-BI. The effect of HMGB1 depletion on LDL transcytosis required SR-BI and SREBP2. Overexpression of HMGB1 caused an increase in LDL transcytosis that was unaffected by inhibition of extracellular HMGB1 or depletion of RAGE (receptor for advanced glycation endproducts)—a cell surface receptor for HMGB1. The effect of HMGB1 overexpression on LDL transcytosis was prevented by knockdown of SREBP2. Loss of HMGB1 caused a reduction in the half-life of SREBP2; incubation with LDL caused a significant increase in nuclear localization of HMGB1 that was dependent on SR-BI. Animals lacking endothelial HMGB1 exhibited less acute accumulation of LDL in the aorta 30 minutes after injection and when fed a high-fat diet developed fewer fatty streaks and less atherosclerosis.

Conclusions:

Endothelial HMGB1 regulates LDL transcytosis by prolonging the half-life of SREBP2, enhancing SR-BI expression. Translocation of HMGB1 to the nucleus in response to LDL requires SR-BI.
Subaortic Membranes in Patients With Hereditary Hemorrhagic Telangiectasia and Liver Vascular Malformations
Authors: Kim Agnes S. , Henderson Katharine J. , Pawar Sumeet , Kim Min Jung , Punjani Shahnaz , Pollak Jeffrey S. , Fahey John T. , Garcia‐Tsao Guadalupe , Sugeng Lissa , Young Lawrence H.
Published: October 2020

Background

Patients with hereditary hemorrhagic telangiectasia have liver vascular malformations that can cause high‐output cardiac failure (HOCF). Known sequelae include pulmonary hypertension, tricuspid regurgitation, and atrial fibrillation.

Methods and Results

The objectives of this study were to describe the clinical, echocardiographic, and hemodynamic characteristics and prognosis of hereditary hemorrhagic telangiectasia patients with HOCF who were found to have a subaortic membrane (SAoM). A retrospective observational analysis comparing patients with and without SAoM was performed. Among a cohort of patients with HOCF, 9 were found to have a SAoM in the left ventricular outflow tract by echocardiography (all female, mean age 64.8±4.0 years). The SAoM was discrete and located in the left ventricular outflow tract 1.1±0.1 cm below the aortic annular plane. It caused turbulent flow, mild obstruction (peak velocity 2.8±0.2 m/s, peak gradient 32±4 mm Hg), and no more than mild aortic insufficiency. Patients with SAoM (n=9) had higher cardiac output (12.1±1.3 versus 9.3±0.7 L/min,
P
=0.04) and mean pulmonary artery pressures (36±3 versus 28±2 mm Hg,
P
=0.03) compared with those without SAoM (n=19) during right heart catheterization. Genetic analysis revealed activin receptor‐like kinase 1 mutations in each of the 8 patients with SAoM who had available test results. The presence of a SAoM was associated with a trend towards higher 5‐year mortality during follow‐up.

Conclusions

SAoM with mild obstruction occurs in patients with hereditary hemorrhagic telangiectasia and HOCF. SAoM was associated with features of more advanced HOCF and poor outcomes.
A Sound Explanation for Motor Cortex Engagement during Action Word Comprehension
Authors: de Zubicaray Greig I. , McMahon Katie L. , Arciuli Joanne
Published: October 2020

Comprehending action words often engages similar brain regions to those involved in perceiving and executing actions. This finding has been interpreted as support for grounding of conceptual processing in motor representations or that conceptual processing involves motor simulation. However, such demonstrations cannot confirm the nature of the mechanism(s) responsible, as word comprehension involves multiple processes (e.g., lexical, semantic, morphological, phonological). In this study, we tested whether this motor cortex engagement instead reflects processing of statistical regularities in sublexical phonological features. Specifically, we measured brain activity in healthy participants using functional magnetic resonance imaging while they performed an auditory lexical decision paradigm involving monosyllabic action words associated with specific effectors (face, arm, and leg). We show that nonwords matched to the action words in terms of their phonotactic probability elicit common patterns of activation. In addition, we show that a measure of the action words' phonological typicality, the extent to which a word's phonology is typical of other words in the grammatical category to which it belongs (i.e., more or less verb-like), is responsible for their activating a significant portion of primary and premotor cortices. These results indicate motor cortex engagement during action word comprehension is more likely to reflect processing of statistical regularities in sublexical phonological features than conceptual processing. We discuss the implications for current neurobiological models of language, all of which implicitly or explicitly assume that the relationship between the sound of a word and its meaning is arbitrary.
Thetis in Identity Crisis
Authors: Alepidou Apostolia
Published: October 2020

This article focuses on Statius’ representation of Thetis in the Achilleid in comparison with her representation in the Iliad. Statius, it is argued, goes against the Homeric tradition, depicting the goddess with features opposite from those she possesses in Homer. Thetis, generally perceived as a modest and ladylike speaker in the Iliad, employs masculine-gendered rhetoric and becomes offensive in the Achilleid; paternal acts linked to Peleus in the Homeric tradition are in Statius’ poem undertaken by Thetis; Homer’s omniscient and powerful goddess is almost ridiculed in Statius: being obsessed with the impossible, i.e. Achilles’ salvation, she repeatedly fails to achieve a possible delay of his doom. Through this technique, Statius inverts Thetis’ traditional character, creating a heroine that fits perfectly in his unconventional epic of cross-dressing and role-play.
Emotions and Reactions regarding Use of Cemeteries/Crematoriums following Loss of a Companion Animal in Spain
Authors: Clemente-Ricolfe José-Serafín , González-Navarro Sergio
Published: October 2020

We present the results of our analysis of the sentiments of guardians in Spain following the death of a companion animal, as well as their potential use of cemeteries/crematoriums, based on a personal survey that was completed by 197 guardians. Factor analysis revealed the existence of three dimensions. The first focused on emotional reactions following a companion animal’s death. The second considered personal relationships that developed between guardians and their companion animals. Finally, the third focused on benefits or value offered by a companion animal. Four segments were obtained by cluster analysis. The largest segment had the strongest intention of using/reusing cemetery or cremation services (3.2 out of 5). It was also the only segment which placed value on emotional reactions upon a companion’s death. The results showed that a strong bond between guardians and companion animals was associated with a higher probability that burial or cremation services would be used.
Lezioni adiafore, errori separativi, contaminazione nascosta
Authors: Reeve Michael D.
Published: October 2020

Some problems that arise over the three concepts named in the title are discussed with the help of passages drawn from classical Latin works.
Targum Jonathan to the Prophets and the Masoretic Cantillations
Authors: Kahana Miriam
Published: October 2020

This article compares the Targum with Masoretic cantillations. The comparison between the different reading traditions shows agreement in everything concerning the division between one verse and the next. Usually, there is agreement in the division within each verse as well, particularly when both the cantillations and the Targum respond to an ideological or exegetical problem in the text. Juxtaposing the cantillations and the Targum in this manner may also reveal aspects of the stages of development of these two interpretative tools in relation to one another. Comparing Targumim and Babylonian cantillations also strengthens the assessment that the Tiberian system of accents was influenced by the Targum in its division of the verses. In addition, examining the way each verse is divided shows how the Targum seems to prefer a subordinate structure even when it translates paratactic clauses.
The Detached Self: Investigating the Effect of Depersonalisation on Self-Bias in the Visual Remapping of Touch
Authors: Farmer Harry , Cataldo Antonio , Adel Nagela , Wignall Emma , Gallese Vittorio , Deroy Ophelia , Hamilton Antonia , Ciaunica Anna
Published: October 2020

There is a growing consensus that our most fundamental sense of self is structured by the ongoing integration of sensory and motor information related to our own body. Depersonalisation (DP) is an intriguing form of altered subjective experience in which people report feelings of unreality and detachment from their sense of self. The current study used the visual remapping of touch (VRT) paradigm to explore self-bias in visual–tactile integration in non-clinical participants reporting high and low levels of depersonalisation experiences. We found that the high-DP group showed an increased overall VRT effect but a no-self-face bias, instead showing a greater VRT effect when observing the face of another person. In addition, across all participants, self-bias was negatively predicted by the occurrence of anomalous body experiences. These results indicate disrupted integration of tactile and visual representations of the bodily self in those experiencing high levels of DP and provide greater understanding of how disruptions in multisensory perception of the self may underlie the phenomenology of depersonalisation.
An Annotated Checklist of Endemic Vascular Plants of the Tian-Shan Mountains in Central Asian Countries

Authors: TOJIBAEV KOMILJON SH. , JANG CHANG GEE , Lazkov GEORGII A. , CHANG KAE SUN , SITPAYEVA GULNARA T. , SAFAROV NEIMATULLO , BESHKO NATALYA YU. , MUKTUBAEYEVA SAULE K. , VESSELOVA POLINA V. , TURAKULOV ISAKUL , ABDURAKHMANOVA YOQUTKHON YU. , NA NU-REE , PARK MIN-SU , CHOI KYUNG , CHOI HYEOK-JAE , OH BYOUNG-UN , OH SEUNG-HWAN
Published: October 2020

A check-list of endemic vascular plants of the Tian-Shan Mountains, including plant distribution along mountain ranges and in Central Asian countries, has been compiled for the first time in this study. The list of Tian-Shan flora consists of 871 endemic species and subspecies. One subspecies belongs to Pinaceae (Pinopsida) and 870 taxa belong to Magnoliidae (dicots, 732 taxa, and monocots, 138 taxa). The endemic flora belongs to 39 families and 187 genera. The largest number of endemics is concentrated in the mountain ranges of Kyrgyzstan (225 national endemics, 507 taxa in total) and Kazakhstan (205 national endemics, 485 taxa in total). Uzbekistan occupies the third position (69 national endemics, 320 taxa in total). Tajikistan has fewer endemics: 82 taxa, of which only 16 taxa are national endemics. The most represented families and genera are: Asteraceae, Fabaceae, Apiaceae, Lamiaceae, and Amaryllidaceae; and Astragalus, Allium, Cousinia, Oxytropis, and Gagea, respectively.
Ptilodactyla exotica Chapin, 1927 in Italy (Coleoptera: Ptilodactylidae)
Authors: NARDI GIANLUCA , BOCCI MAURA , POGGI ROBERTO
Published: October 2020

Ptilodactyla exotica Chapin, 1927 is a subcosmopolitan synanthropic species introduced to Europe with tropical ornamental plants. It is here firstly recorded from central Italy (Tuscany region), and its Italian chronogeonemy (1940–2016) is summarized. Most records come from the Genoa province (Northern Italy, Liguria region), where this species was repeatedly collected in the period 1940–1999.
Distinguishing Characteristics of Tornadic and Nontornadic Supercell Storms from Composite Mean Analyses of Radar Observations
Authors: Homeyer Cameron R. , Sandmæl Thea N. , Potvin Corey K. , Murphy Amanda M.
Published: October 2020

An improved understanding of common differences between tornadic and nontornadic supercells is sought using a large set of observations from the operational NEXRAD WSR-88D polarimetric radar network in the contiguous United States. In particular, data from 478 nontornadic and 294 tornadic supercells during a 7-yr period (2011–17) are used to produce probability-matched composite means of microphysical and kinematic variables. Means, which are centered on echo-top maxima and in a horizontal coordinate system rotated such that storm motion points in the positive x dimension, are created in altitude relative to ground level at times of peak echo-top altitude and peak midlevel rotation for nontornadic supercells and times at and prior to the first tornado in tornadic supercells. Robust differences between supercell types are found, with consistent characteristics at and preceding tornadogenesis in tornadic storms. In particular, the mesocyclone is found to be vertically aligned in tornadic supercells and misaligned in nontornadic supercells. Microphysical differences found include a low-level radar reflectivity hook echo aligned with and ~10 km right of storm center in tornadic supercells and displaced 5–10 km down-motion in nontornadic supercells, a low-to-midlevel differential radar reflectivity dipole that is oriented more parallel to storm motion in tornadic supercells and more perpendicular in nontornadic supercells, and a separation between enhanced differential radar reflectivity and specific differential phase (with unique displacement-relative correlation coefficient reductions) at low levels that is more perpendicular to storm motion in tornadic supercells and more parallel in nontornadic supercells.
Alternative Entry Points for Adaptation: Examples from Vanuatu
Authors: Westoby Ross , Clissold Rachel , McNamara Karen E.
Published: October 2020

As climate change accelerates, effective adaptation is an urgent and unavoidable priority. Bottom-up approaches such as community-based adaptation have been portrayed as the panacea. Recent studies are, however, highlighting the ongoing and inherent issues with normative “community” conceptualizations that assume a geographically bound, temporally fixed, and harmonious unit. Despite documentation on the negative impact these problematic assumptions can have on adaptation outcomes, adaptation at the community scale remains the preferred option for project delivery in highly exposed places such as the Pacific Islands region. More creative entry points that are less charged with problematic assumptions are needed at the local scale. This paper draws from three examples in Vanuatu to offer compelling alternative entry points for adaptation: 1) a rural technical college embedded within an Anglican mission village, 2) a whole-of-island approach, and 3) the “collective of vendors” at marketplaces. We offer hope by identifying ways to expand on and complement existing, restricted notions of community and, through this, to improve adaptation outcomes.
Special Collection on Ecological and Evolutionary Approaches to Cancer Control: Cancer Finds a Conceptual Home
Authors: Whelan Christopher J. , Gatenby Robert A.
Published: October 2020

Despite a century of intense investigation, cancer biology and treatment remain plagued by unanswered questions. Even basic questions regarding the fundamental forces driving the formation of cancer remain controversial. Recent approaches view cancer in the context of a complex web of interactions among cancer cells of the tumor, together with their interactions with the many cells and constituents of the complex and highly dynamic tumor microenvironment. As seen in this special collection, we believe that viewing cancer as a process of evolution driven by ongoing ecological processes playing out within a dynamic environment offers many insights and potential new pathways for cancer control.
An 8 miRNA-Based Risk Score System for Predicting the Prognosis of Patients With Papillary Thyroid Cancer
Authors: Yi Wanwan , Liu Jin , Qu Shuping , Fan Hengwei , Lv Zhongwei
Published: October 2020

Background:

Dysregulation of microRNAs (miRNAs) in papillary thyroid cancer (PTC) might influence prognosis of PTC. This study is aimed to develop a risk score system for predicting prognosis of PTC.

Methods:

The miRNA and gene expression profiles of PTC were obtained from The Cancer Genome Atlas database. PTC samples were randomly separated into training set (n = 248) and validation set (n = 248). The differentially expressed miRNAs (DE-miRNAs) in the training set were screened using limma package. The independent prognosis-associated DE-miRNAs were identified for building a risk score system. Risk score of PTC samples in the training set was calculated and samples were divided into high risk group and low risk group. Kaplan-Meier curves and receiver operating characteristic (ROC) curve were used to assess the accuracy of the risk score system in the training set, validation set and entire set. Finally, a miRNA-gene regulatory network was visualized by Cytoscape software, followed by enrichment analysis.

Results:

Totally, 162 DE-miRNAs between tumor and control groups in the training set were identified. An 8 independent prognosis-associated DE-miRNAs, (including miR-1179, miR-133b, miR-3194, miR-3912, miR-548j, miR-6720, miR-6734, and miR-6843) based risk score system was developed. The area under ROC curve in the training set, validation set and entire set was all above 0.93. A miRNA-gene regulatory network involving the 8 DE-miRNAs were built and functional enrichment analysis suggested the genes in the network were significantly enriched into 13 pathways, including calcium signaling pathway and hedgehog signaling pathway.

Conclusion:

The risk score system developed this study might be used for predicting the prognosis of PTC. Besides, the 8 miRNAs might affect the prognosis of PTC via hedgehog signaling pathway and calcium signaling pathway.
The Video Camera Spoiled My Ethnography: A Critical Approach
Authors: Gregory Katherine
Published: October 2020

As videography and other media technologies are normalized in the field of qualitative methods for the purpose of data collection, there is a growing need to discuss the benefits and limitations of these data collection tools. This article chronicles an ethnographic video study focused on the experiences of Muslim adults living in the Netherlands, and why the author opted to end the project. Issues focus on reckoning with the imperial gaze of the camera, performative behavior of participants before the camera and interdisciplinary tensions the researcher faced from conflicting trainings as a qualitative methodologist and media practitioner.
Safety of a strategy combining D-dimer testing and whole-leg ultrasonography to rule out deep vein thrombosis
Authors: Fronas Synne G. , Jørgensen Camilla T. , Dahm Anders E. A. , Wik Hilde S. , Gleditsch Jostein , Raouf Nezar , Holst René , Klok F. A. , Ghanima Waleed
Published: October 2020

Guidelines for the diagnostic workup of deep vein thrombosis (DVT) recommend assessing the clinical pretest probability before proceeding to D-dimer testing and/or compression ultrasonography (CUS) if the patient has high pretest probability or positive D-dimer. Referring only patients with positive D-dimer for whole-leg CUS irrespective of pretest probability may simplify the workup of DVT. In this prospective management outcome study, we assessed the safety of such a strategy. We included consecutive outpatients referred to the Emergency Department at Østfold Hospital, Norway, with suspected DVT between February 2015 and November 2018. STA-Liatest D-Di Plus D-dimer was analyzed for all patients, and only patients with levels ≥0.5 µg/mL were referred for CUS. All patients with negative D-dimer or negative CUS were followed for 3 months to assess the venous thromboembolic rate. One thousand three hundred ninety-seven patients were included. Median age was 64 years (interquartile range, 52-73 years), and 770 patients (55%) were female. D-dimer was negative in 415 patients (29.7%) and positive in 982 patients (70.3%). DVT was diagnosed in 277 patients (19.8%). Six patients in whom DVT was ruled out at baseline were diagnosed with DVT within 3 months of follow-up for a thromboembolic rate of 0.5% (95% confidence interval, 0.2-1.2). A simple diagnostic approach with initial stand-alone D-dimer followed by a single whole-leg CUS in patients with positive D-dimer safely ruled out DVT. We consider this strategy to be a valuable alternative to the conventional workup of DVT in outpatients. This trial was registered at www.clinicaltrials.gov as #NCT02486445.
Solitary pulmonary nodule imaging approaches and the role of optical fibre-based technologies
Authors: Fernandes Susan , Williams Gareth , Williams Elvira , Ehrlich Katjana , Stone James , Finlayson Neil , Bradley Mark , Thomson Robert R. , Akram Ahsan R. , Dhaliwal Kevin
Published: October 2020

Solitary pulmonary nodules (SPNs) are a clinical challenge, given there is no single clinical sign or radiological feature that definitively identifies a benign from a malignant SPN. The early detection of lung cancer has a huge impact on survival outcome. Consequently, there is great interest in the prompt diagnosis, and treatment of malignant SPNs. Current diagnostic pathways involve endobronchial/transthoracic tissue biopsies or radiological surveillance, which can be associated with suboptimal diagnostic yield, healthcare costs and patient anxiety. Cutting-edge technologies are needed to disrupt and improve, existing care pathways. Optical fibre-based techniques, which can be deliveredviathe working channel of a bronchoscope orviatransthoracic needle, may deliver advanced diagnostic capabilities in patients with SPNs. Optical endomicroscopy, an autofluorescence-based imaging technique, demonstrates abnormal alveolar structure in SPNsin vivo. Alternative optical fingerprinting approaches, such as time-resolved fluorescence spectroscopy and fluorescence-lifetime imaging microscopy, have shown promise in discriminating lung cancer from surrounding healthy tissue. Whilst fibre-based Raman spectroscopy has enabled real-time characterisation of SPNsin vivo. Fibre-based technologies have the potential to enablein situcharacterisation and real-time microscopic imaging of SPNs, which could aid immediate treatment decisions in patients with SPNs. This review discusses advances in current imaging modalities for evaluating SPNs, including computed tomography (CT) and positron emission tomography-CT. It explores the emergence of optical fibre-based technologies, and discusses their potential role in patients with SPNs and suspected lung cancer.