bluuebunny/crossref_metadata_2025 huggingface dataset:
A Novel Approach to Integrative Concussion Rehabilitation: A Pragmatic Study
Authors:   Intermountain Rehabilitation Services, Park City Hospital, Intermountain Health, USA, Ziaks Lauren , Tucker Jenna ,   Department of Physical Therapy, Kean University, USA, Koc Thomas ,   Department of Physical Therapy, Kean University, USA, Dowdell Meaghan ,   Department of Physical Therapy, Kean University, USA, Giorello Giana ,   Department of Physical Therapy, Kean University, USA
Published: February 2024

Purpose: The purpose of this study is to evaluate the effectiveness of the novel Ziaks Integrative Neurological Concussion (ZINC) Protocol in evaluating and treating persistent post-concussion symptoms. Methods: Individuals with concussion were systematically evaluated for neurological impairments and subsequently received six modules of integrative and progressive therapies. Treatment addressed motor function impairment, oculomotor and binocular vision deficits, and central vestibular deficits while incorporating postural stability, dual task and cognitive loading skills and providing instruction in cardiovascular exercise to promote autonomic stability. Results: Of 30 patients, 15 completed all 6 protocol modules for inclusion in data analysis. Mean treatment duration was 6.6 (SD±.99) visits over 69.53 days (SD±21.92). The Post-Concussion Symptom Scale and Dizziness Handicap Inventory outcomes from pre- to post-treatment achieved clinical and statistical significance. Statistical significance was achieved for the Brain Injury Vision Symptom Survey, Brock String near point of convergence, King Devick and the novel binocular vision screening tool. Conclusions: A structured, integrative, and progressive rehabilitation program addressing the vestibulo-oculomotor and motor function domains of concussion may be effective in the management of persistent post-concussion symptoms. Impact Statement: This study details one potential comprehensive and sequential method to integrate the neurological domains of concussion rehabilitation while screening for impairments in the physical domains. There is a gap in knowledge regarding the most effective timing, sequencing, and implementation of intervention methods across the 4 concussion domains. This study provides the groundwork for future research to establish treatment protocols aimed to efficiently reduce symptoms associated with persistent post-concussion symptoms.
Boosting the biodegradation and bioactivity of PBS-DLS copolymers via incorporation of PEG
Authors: Zarei Moein , Michalkiewicz Beata , El Fray Miroslawa
Published: February 2024

Biodegradable polymers play a crucial role in the development of materials for biomedical applications. This study investigates the enzymatic biodegradation, bioactivity, and cytotoxicity of poly(butylene succinate-dilinoleic succinate) (PBS-DLS) copolymers modified with poly(ethylene glycol) (PEG). Two copolymer variations with different segmental compositions (70 wt% and 60 wt% of hard segments) were synthesized. After modifying the copolymers with PEG, the presence of a lipase catalyst accelerated degradation after 20 days, evidenced by reduced residual content. Gel permeation chromatography analysis showed up to 40% decrease in molecular weight, while gravimetric analysis indicated a mass loss of up to 10% during enzymatic degradation. Morphological examination revealed that the enzymatic breakdown, facilitated by hydrolase activity (boosted by the presence of PEG), resulted in surface erosion, holes, cracks and changes in spherulitic morphology. It highlights the tunable degradation pathways of these copolymers. Bioactivity studies demonstrated the formation of biomimetic calcium/phosphate (Ca/P) crystals, with varying stoichiometry based on segmental composition. Copolymers with higher crystallinity (70 wt% hard segments) favored tricalcium phosphate-like crystal formation, while those with lower crystallinity (60 wt% hard segments) were more susceptible to hydroxyapatite precipitation. In vitro cytotoxicity tests using mice fibroblasts exhibited excellent cell viability and attachment for all copolymers. These findings highlight the significance of these copolymers in developing biodegradable materials for medical applications. The ability to control degradation through PEG modification, along with their bioactivity and cell compatibility, positions them as promising candidates for diverse biomedical applications.
Overview of nanotherapeutics for bacterial infections
Authors: Muñoz-López José , Lopes Cátia D. F. , Batalha Iris L.
Published: February 2024

The rapid emergence of antibiotic-resistant bacteria poses one of the greatest threats to public health as conventional therapies and commercial antibiotics are dropping their effectiveness. In the race for the discovery of new strategies to prevent a scenario in which commonplace infections prove fatal, nanomaterials stand in the limelight due to their unique physicochemical properties that can be seized to overcome common resistance mechanisms. Nanoparticle-driven drug delivery emerges as a beacon of hope, shielding antibiotics from enzymatic degradation, enhancing their targeted delivery to afflicted sites in therapeutically potent concentrations, and minimising undesired side effects. Drugs can either be entrapped or chemically conjugated to nanoparticles, with the latter offering a myriad of possibilities in orchestrating spatiotemporal controlled release of the therapeutic payload. Meanwhile, nanomaterials can also display intrinsic antimicrobial properties, either by direct disruption of bacterial cell membranes (e.g., nanoparticles functionalised with cationic groups) or by instigating the generation of ROS (e.g., metallic nanoparticles). The clinical implementation of nanotherapeutics still faces considerable challenges, mainly related with their complex chemistry and polydispersity, which poses difficulties related to cost-effectiveness, scale-up, and Chemistry, Manufacturing, and Controls (CMC) management. Still, the development of computational approaches allowing a better understanding of nano-bio interactions and predictive biodistribution, pharmacokinetics, and toxicology, along with a harmonised international regulatory framework, is expected to facilitate clinical translation in the near future.
Simple Synthesis of Unnatural Amino Acids via Ni/Ag-Electrocatalytic Cross-Coupling
Authors: Laudadio Gabriele , Neigenfind Philipp , Chebolu Rajesh , Blasczak Vanna D. , Madirala Shambabu Joseph , Palkowitz Maximilian D. , Bolduc Philippe N. , Nicastri Michael C. , Puthukanoori Ravi Kumar , Paraselli Bheema Rao , Baran Phil S.
Published: February 2024

A simple protocol is outlined herein for rapid access to enantiopure unnatural amino acids from trivial glutamate and aspartate precursors. The method relies on Ag/Ni-electrocatalytic decarboxylative coupling and can be rapidly conducted in parallel (24 reactions at a time) to ascertain coupling viability followed by scale-up for the generation of useful quantities of UAAs for exploratory studies.
Interzeolite transformation through cross-nucleation
Authors: Chu-Jon Carlos , Bertolazzo Andressa , Banik Suvo , Sankaranarayanan Subramanian , Molinero Valeria
Published: February 2024

Polymorph selection and efficient crystallization are cen-tral goals in zeolite synthesis. Crystalline seeds are used for both purposes. The seed’s crystal structure may not always match the daughter zeolite’s. For example, zeolite CHA seeds speed-up 24-fold zeolite AFI’s synthesis. It was proposed that structural elements in CHA promote AFI nucleation. However, these zeolites do not have a common crystal plane or composite building units (CBUs). Here we present the first molecularly resolved investigation of mechanism of seed assisted zeolite syn-thesis. We use molecular simulations to elucidate how CHA promotes AFI. Consistent with experiments, we find that CHA increases AFI’s nucleation 24-fold. The speed up arises from cross-nucleation of AFI on the (001) face of CHA. The CHA/AFI interface is connected by an interfacial transition layer with order distinct from par-ent and daughter. We find that stand-alone CBUs of CHA do not assist in AFI nucleation, implying that the integrity of the crystalline seed is key for increased effi-ciency and selectivity in zeolite synthesis.
Valorisation of Brewer’s Spent Grain: Lignocellulosic Fractionation and its Potential for Polymer and Composite Material Applications
Authors: Pérocheau Arnaud Sacha
Published: February 2024

An estimated amount of 40 million t/a of Brewer’s Spent Grain (BSG) is produced and is currently used for low-value valorisation or disposed of in landfills. In an era where non-renewable resources stocks are depleting and products such as plastics accumulate in the environment, the need for more sustainable resources, products and production strategies is substantial. Lignocellulosic biomasses, when their production is not in competition with the food sector, could be an answer to this challenge through the use of biorefineries. This review aims at gathering the advantages of BSG’s valorisation through the prism of building block production for polymer synthesis and its use as natural filler for composite material. BSG will also be compared to other biomasses by exploring the conditions available for its fractionation. The examples listed herein depict promising valorisation strategies with a myriad of building blocks available for the synthesis of organic compounds and polymers. The use of BSG as filler in composite materials, however, faces limitations in terms of performances that will need to be tackled in future works. A lot of research has yet to be performed on BSG’s valorisation to help shift the polymer and material industry towards a more sustainable horizon.
Metal Ions-Induced Unusual Stability of the Metastable Vesicle-like Intermediates Evolving in the Self-Assembly Process of Phenylalanine: The Role of Hydrophobic Interaction, Metal-Coordination, and Surface Charge Inversion
Authors: BAGCHI DEBANJAN , MAITY AVIJIT , CHAKRABORTY ANJAN
Published: February 2024

The underlying mechanism and the intermediates formation in the self-assembly of aromatic amino acids, peptides and proteins remain elusive despite numerous reports. We, for the first time, report that one can modulate the stability of the intermediates by tuning the metal ions-amino acid interaction of carboxybenzyl (Z)-protected phenylalanine (ZF). The microscopic and spectroscopic investigations reveal that the bivalent metal ions lead to the formation of fibrillar networks after a certain interval similar to blank ZF, whereas the trivalent ions develop vesicle-like intermediates which do not undergo fibrillation for a prolonged time. The time-lapse measurement of surface charge reveals that the surface charge of blank ZF and in the presence of bivalent metal ions alters from negative value to zero implying unstable intermediates leading to the fibril network. Strikingly, a prominent charge inversion from an initial negative to a positive value in the presence of trivalent metal ions imparts unusual stability to the metastable intermediates.
ГРАМАТИЧНІ ДОМІНАНТИ В ТЕКСТІ ОСВІТНЬОЇ РЕКЛАМИ
Authors: Чжан Менвей
Published: February 2024

Освітня реклама – малодосліджена ділянка рекламного дискурсу для мовознавців. Активізація рекламної діяльності у сфері освітніх послуг зумовлена розвитком ринкових відносин, комерціалізацією освіти, входженням навчальних закладів у світовий освітній простір, суспільно-політичними змінами в суспільстві. Рівновага між раціональністю та емоційністю є важливою ознакою текстів, що рекламують заклади вищої освіти. Прагненню створити позитивний образ університету, досягти прагматичного ефекту підпорядковані мовні засоби рекламного тексту проспекту, буклета, листівки у всіх його структурних компонентах і на всіх мовних рівнях. Морфологічні одиниці, взаємодіючи з елементами лексичного та синтаксичного рівнів, творять цілісний і виразний рекламний текст. Аналіз рекламних текстів дав змогу відтворити загальну картину морфологічних ресурсів, визначити продуктивність лексико-граматичних класів та їхню роль в основних частинах, смислове, емоційно-оцінне навантаження, комунікативно-прагматичний потенціал. Проаналізовані тексти освітньої реклами засвідчили найпродуктивніші частини мови та виявили відмінність від загальноприйнятого твердження дослідників комерційної реклами про іменник і дієслово як ключові частини мови. Продуктивність основних морфологічних одиниць у текстах освітньої реклами відображаємо таким спадним ланцюжком: «іменники – прикметники – дієслова – прислівники – займенники». Серед іменників переважають абстрактні іменники та іменники із вторинним лексичним значенням дії. Такі іменники відображають концептуальні складники освіти, навчально-наукової діяльності, результати здобуття освіти. Дієслова роблять текст не так динамічним, як діяльним, оскільки називають дії-навчання, дії-науку, дії-результати. Прикметники найповніше забезпечують оцінно-емоційну складову частину рекламних текстів вищих освітніх закладів. Якісні прикметники слугують для іміджевої характеристики університетів, семантизують високу позитивну оцінку за різними оцінювальними ознаками; відносні – конкретизують іменники, що відтворюють розгалужену систему освітньої діяльності. Прислівники вжито найчастіше з метою оцінної характеристики дії, вираженої дієсловом. Для досягнення успіху реклами, максимального привернення уваги цільової авдиторії використовують займенники. Вони реалізують свій впливовий потенціал як маркери інтимізації передусім у коротких слоганах або завершальних фразах, безпосередньо звернених до реципієнта. Цифрове оформлення числівників відображає змістовний, рідше – експресивний бік інформації, вербальне слугує для вираження унікальності навчального закладу, тобто діє як іміджевий засіб.
ОБРАЗНИЙ КОМПОНЕНТ КОНЦЕПТУ MURDER У РОМАНІ Р. ОСМАНА «КЛУБ ВБИВСТВ ПО ЧЕТВЕРГАХ»
Authors: Шульженко К. А. , Єсипенко Н. Г.
Published: February 2024

Наукова стаття витоками сягає у сферу когнітивної лінгвістики та досліджує структурні особливості концепту ВБИВСТВО. Досліджуючи цю концепцію, автори виявляють складну взаємодію між структурними компонентами та образними елементами, втілену насамперед через концептуальні метафори. У результаті аналізу було виявлено метафоричні відображення, пов’язані з концептом ВБИВСТВО, що охоплюють метафори кольору, темряви, розслідування, плану й таємниці. Насамперед концепт ВБИВСТВО наповнений сильними емоціями, часто знаходить своє відображення в метафоричному вигляді. Центральне місце в цьому розслідуванні займають метафоричні епітети, використані для опису процесу вбивства та його зображення в романах. Такі епітети, як «ідеальний», «невирішений», «безкарний», несуть у собі емоційний і засуджуючий підтекст, що відображає масштаб розповіді та складність цієї концепції. Аналіз прикладів із роману «Клуб вбивств по четвергах» ілюструє поширеність використання таких понять та демонструє негативні конотації, зазвичай пов’язані зі злочином у детективному жанрі. Більше того, у статті виокремлюється метафорична асоціація ВБИВСТВО – це КОЛІР, наголошуючи на переважному використанні темних кольорів для передачі негативних конотацій, пов’язаних із навмисним вбивством. Темні, чорні й сині тони символізують похмурий характер поняття та контрастують з яскравими кольорами, підкреслюючи чистоту і спогади про певні місця. Більше того, концептуальна основа поширюється на дослідження ВБИВСТВО як ПЛАН і підкреслює ретельне планування та його виконання в романі. Це мапування розглядається як послідовність дій, і в аналізі особлива увага приділяється плануванню, вбивствам та наслідкам, що дає уявлення про природу злочинів і мислення порушників закону. Через заглиблення в метафоричні уявлення вбивства стаття сприяє кращому розумінню концепту ВБИВСТВО та його глибокому впливу на читачів. Дослідження метафоричних епітетів, предикатів та конвенційних метафор розкриває багатогранну природу цього поняття в літературі та когнітивній лінгвістиці.
DETERMINANTS OF ENVIRONMENTAL SUSTAINABILITY DISCLOSURE
Authors:   Accountancy Department, Auchi Polytechnic, Auchi,, IZEVBEKHAI Monday Olade , MOMODU Abudukerimu ,   Department of Business Administration and Management, Auchi Polytechnic, Auchi
Published: February 2024

This study examined the determinants of environmental sustainability disclosure. The broad objective of the study was to examine whether board size, board gender diversity and ownership concentration determine environmental disclosure of listed oil and gas firms in Nigeria. Data were collected from published accounts of studied firms using the purposive sampling technique to select a sample size of eight (8) oil and gas firms for the study. The log-linear regression analysis was used to analyze the data obtained. Findings revealed that board gender diversity and ownership concentration have significant effect on environmental disclosure of listed oil and gas firms in Nigeria. The study concludes that concern of environmental disclosure in the financial statements of firms is fundamental and imperative. It is indispensable that the activities of the firm in the environment in which they operate in terms of finance are well documented and accounted for the users of the report to evaluate. The study recommends that size of the board should be regulated to portray the intentions of the firm to further pursue environmental disclosure course and that female board members should be incorporated into the board to balance the compassionate rationale of the board
Medicina evolutiva en paciente crítico
Authors: Bello Castillo Maria Carmen , Viteri Ruiz Marvi Alexander , Verduga Andrade Lidia Roxana , Llano Pila Sandra Maricela
Published: February 2024

La medicina evolucionista está asociada a los aspectos genéticos y el desarrollo adaptativo del cuerpo humano, trata de distinguir hoy en día, si una manifestación de enfermedad es un problema que debe tratarse o es, más bien, una defensa producto de la selección natural, que no es necesario o es contraproducente bloquear, por su parte la Medicina Critica (MC) es esa parte de la medicina que encargada de los pacientes cuya patología ha alcanzado su estado lo suficientemente grave o severo que se convierte en un peligro vital, actual o potencial, susceptible de recuperabilidad. La biología evolutiva se ha desarrollado hasta llegar a ser un pensamiento fundamental, necesario para la educación médica, en teorías tales como: el envejecimiento, la coevolución patógeno-huésped y adaptaciones a cambios ambientales, entre otros. Surge, en esta ocasión la inquietud académica de estudiar, hasta donde existen hallazgos acerca de la aplicación de criterios para el paciente crítico visto desde la medicina evolutiva y la medicina intensiva. Para alcanzar el objetivo de la presente investigación se utiliza la investigación bibliográfica, aplicando criterios de búsqueda en los repositorios científicos-académicos que deriven luego de utilizar los descriptores "medicina evolutiva en paciente crítico" delimitando por idioma y fecha. Se seleccionan los trabajos por orden de relevancia, publicados entre los años 2018-2024 para obtener los resultados más recientes. Estas contribuciones influyeron en el pensamiento evolutivo de los investigadores y proporcionaron ideas siempre nuevas para explicar el desarrollo de la virulencia de los microorganismos, la resistencia a los antibióticos, la menopausia y el conflicto genómico materno-fetal en nutrición (preeclampsia). También explica el desarrollo de cánceres reproductivos en las sociedades postindustriales como resultado de las fluctuaciones en el ciclo menstrual. El campo de la ciencia está pasando de una fase inicial dominada por la especulación a una fase más rigurosa en la que se prueban alternativas explícitas. Aunque el enfoque evolutivo es atractivo y aparece como una alternativa interesante al tratamiento convencional, no es del todo la respuesta adecuada para sustituir otras intervenciones probadas, el tratamiento de un paciente crítico debe ser lo más objetivo y demostrable posible.
Degeneración de los tejidos del cerebro en base a la demencia frontón/temporal
Authors: Fernandez Champang Angie Fiorella , Rodríguez Medina Andrés Sebastián , León Ponce Samuel Andrés , Alava Farah Sebastián Alejandro
Published: February 2024

La demencia frontotemporal (DFT) es un fenómeno neurodegenerativo complejo que afecta los lóbulos frontal y temporal y se manifiesta por cambios en la personalidad, el comportamiento y el lenguaje. La revisión de la literatura analiza la fisiopatología, etiología y métodos de diagnóstico, enfatizando la acumulación de proteínas anormales y factores genéticos como factores clave en la patogénesis de la enfermedad. El objetivo de la investigación es identificar marcadores biológicos y métodos de tratamiento eficaces. La epidemiología destaca la necesidad de estudios especiales, por ejemplo, en Ecuador, donde la FTD es responsable de una proporción significativa de los casos de demencia. La metodología utilizada, basada en una revisión integral y un análisis temático, proporciona una imagen integral del progreso actual. Las manifestaciones clínicas incluyen cambios en la personalidad, el comportamiento y las habilidades motoras, mientras que el diagnóstico implica una evaluación exhaustiva con pruebas neuropsicológicas y estudios de neuroimagen. En conclusión, el estudio tiene como objetivo abordar las complejidades de la FTD, responder a la pregunta central de qué causa la degeneración cerebral y promover avances terapéuticos que beneficien a quienes la padecen y arrojen luz sobre la neurodegeneración en general.
ANALISIS KESULITAN BELAJAR MEMBACA PERMULAAN PADA SISWA KELAS I SD NEGERI 02 KUTA KECAMATAN BELIK KABUPATEN PEMALANG
Authors: Septiadi Kurnia , Dewi Endah Rita Sulistya , Fajriyah Khusnul
Published: February 2024

Konteks penelitian yang mendorong penelitian ini adalah pentingnya kemampuan belajar membaca permulaan pada siswa dijenjang SD. Selanjutnya ketrampilan membaca daianggap sangat penting bagi seorang siswa karena membaca merupakan salah satu aktifitas penting dalam hidup yang dapat dikatakan bahwa semua proses belajar didasarkan pada kemampuan membaca. Penelitian ini bertujuan menganalisis kesulitan membaca permulaan pada siswa kelas I sekolah dasar. Jenis penelitian yang digunakan adalah penelitian kualitatif. Tujuan digunakannya metode kualitatif adalah untuk mendapatkan data yang mendalam. Data yang diperoleh melalui observasi, wawancara, lembar keterampilan membaca siswa, dokumentasi. Dari penelitian yang dilakukan menunjukan kesulitan membaca permulaan yang dialami siswa kelas 1 kesulitan membaca huruf alfabet, kesulitan membaca gabungan dari huruf konsonan, kesulitan membaca kata, kesulitan membaca kalimat, kelancaran membaca. Simpulan dari penelitian ini adalah kesulitan membaca permulaan dikarenakan kurangnya minat belajar siswa dalam membaca, kurangnya bimbingan belajar dari orang tua dalam proses membaca permulaan, dan pengaruh faktor lingkungan dalam proses belajar membaca permulaan pada siswa.           Kata Kunci: analisis, kesulitan belajar, membaca permulaan.
PENGEMBANGAN MEDIA PEMBELAJARAN POP-UP BOOK MATERI MENGENAL BANGUN RUANG UNTUK SISWA KELAS IV SDN 02 PAMOTAN
Authors: Rizkiawan Rachmad , Purnamasari Veryliana , Prasetyo Singgih Adhi
Published: February 2024

Latar belakang yang mendorong penelitian ini adalah kurangnya pemanfaatan media pembelajaran dalam pembelajaran matematika di kelas, yang mengakibatkan kejenuhan dan pemahaman yang rendah pada peserta didik. Rumusan masalah dalam penelitian ini adalah (1) Bagaimana validitas media Pop-Up Book materi bangun ruang untuk siswa kelas IV sekolah dasar? (2) Bagaimana pengembangan media Pop-Up Book materi bangun ruang untuk siswa kelas IV sekolah dasar. Tujuan yang hendak dicapai dalam penelitian ini adalah (1) Untuk mengetahui validitas media Pop-Up Book materi bangun ruang untuk siswa kelas IV sekolah dasar, (2) Untuk mengetahui pengembangan media Pop-Up Book materi bangun ruang untuk siswa kelas IV sekolah dasar. Jenis penelitian ini adalah R&D dengan populasi siswa kelas IV SD Negeri 02 Pamotan. Sampel terdiri dari 28 siswa yang menjadi anggota populasi. Data dikumpulkan melalui angket, dokumentasi, dan observasi. Validasi oleh ahli media dan materi menunjukkan kategori "sangat layak" dengan skor 97% dan 90,6% secara berurutan. Uji lapangan menunjukkan skor 90,4% dari siswa dan 98,2% dari guru kelas IV SD N 02 Pamotan. Hasil penelitian ini merekomendasikan penggunaan media Pop-Up Book Bangun Ruang sebagai alat pembelajaran yang beragam untuk meningkatkan kualitas pembelajaran bagi guru dan siswa.
PENGEMBANGAN MEDIA PEMBELAJARAN INTERAKTIF BERBASIS APLIKASI ANDROID SIPINTAR PADA MATA PELAJARAN MATEMATIKA MATERI BANGUN DATAR KELAS IV SEKOLAH DASAR
Authors: Oliviana Sinta , Wardana Muhammad Yusuf Setya , Widyaningrum Ari
Published: February 2024

Tujuan penelitian ini ialah mengetahui pengembangan, kelayakan dan keberterimaan media SIPINTAR dalam mata pelajaran matematika materi bangun datar bagi siswa kelas IV sekolah dasar. Metode Research and Development dipergunakan pada penelitian ini dengan menggunakan penngembangan ADDIE yang terdapat 5 tahap yakni analysis, design,development, implementation, evaluation. Data yang didapatkan dari wawancara dan angket. Perolehan penelitian ini menghasilkan media pembelajaran berbasis aplikasi android untuk mata pelajaran matematika materi bangun datar. Media pembelajaran ini merupakan pengembangan dari media powerpoint yang di export dalam bentuk aplikasi sehingga bisa diakses pada semua sistem andorid. Perolehan validasi ahli media satu menghasilkan persentase kevalidan 84%, sementara ahli materi dua menghasilkan persentase 94% dengan kategori keduanya “sangat valid”. Perolehan validasi ahli materi satu menghasilkan persentase 81,33%, sementara validasi ahli materi kedua menghasilkan persentase 93,33% dengan kategori “sangat valid”. Pada uji coba lapangan mendapat perolehan dari anget guru 95% dengan kategori “sangat baik” dan respon siswa 97,69% dengan kategori “sangat baik”. Dari persentase dari uji tersebut, maka mmedia SIPINTAR diterima dengan sangat baik dan layak dijadikan media pembelajaran di kelas IV sekolah dasar.
PENGEMBANGAN E-LKPD BERBASIS LIVEWORKSHEETS PADA MATA PELAJARAN MATEMATIKA MATERI SUDUT KELAS IV SEKOLAH DASAR
Authors: Cahyaningrum Fadhilah , Huda Choirul , Sundari Riris Setyo
Published: February 2024

Tujuan yang hendak dicapai dalam penelitian ini adalah untuk mengetahui karakteristik pengembangan produk E-LKPD berbasis Liveworksheets pada mata pelajaran matematika materi sudut kelas IV SD dan untuk mengetahui kevalidan dan kepraktisan produk E-LKPD berbasis Liveworksheets pada mata pelajaran matematika materi sudut kelas IV SD.Jenis penelitian ini adalah penelitian dan pengembangan atau Research and Development (R&D) yang mengacu pada model pengembangan ADDIE. Subjek penelitian ini adalah siswa kelas IV SDN  02 Ampelgading yang berjumlah 14 peserta didik. Hasil penelitian diperoleh dari validasi ahli media dan ahli materi serta angket tanggapan dari guru dan peserta didik. Hasil dari 2 validator media mendapat nilai dengan rata-rata 98% dengan hasil perhitungan realibitas menghasilkan nilai 98% sedangkan hasil dari 2 validator materi mendapat nilai dengan rata-rata 96,65% dengan hasil perhitungan reliabilitas menghasilkan nilai 99,3%. Disimpulkan bahwa data atau nilai akhir dinyatakan valid dan realibel. Hasil tanggapan guru mendapat hasil 96% sedangkan hasil tanggapan peserta didik mendapat hasil 98%. Dapat disimpulkan bahwa E-LKPD berbasis LiveworksheetsIni praktis dan layak untuk digunakan.
Syntax and Prosody of Split Scrambling: an Experimental Approach
Authors:   Lomonosov Moscow State University, Belova Daria
Published: February 2024

The work is devoted to the experimental study of structures with split scrambling. With the help of acceptability assessment methods with the use of the Likert scale, self-paced reading, and prosodic experiment, the possibility of separating the left element (determinator or possessor) from the noun head within DP or PP is compared with the separation of the nominal head from its complement (dependent infinitive or prepositional phrase). The results show that separating the head for Russian speakers is not only possible but also rated higher than separating the left element from the head. This pattern is explained by the requirements of the information structure: the left element that has been fronted cannot form the only topic of the clause. The low scores are consistent with existing experimental studies; however, the results of the reading time appear to be inconsistent with existing views about the cognitive load required to process split sentences.
Scaled Down Lean BERT-like Language Models for Anaphora Resolution and Beyond
Authors:   NTR Labs, Bolshakov Vladislav , Kolobov Rostislav , Borisov Eugene , Mikhaylovskiy Nikolay , Mukhtarova Gyuli
Published: February 2024

We study performance of BERT-like distributive semantic language models on anaphora resolution and related tasks with the purpose of selecting a model for on-device inference. We have found that lean (narrow and deep) language models provide the best balance of speed and quality for word-level tasks, and opensource1 RuLUKE-tiny and RuLUKE-slim models we have trained. Both are significantly (over 27%) faster than models with comparable accuracy. We hypothesise that the model depth may play a critical role for performance as, according to recent findings each layer behaves as a gradient descent step in autoregressive setting.
Exploring Evaluation Techniques in Controlled Text Generation: A Comparative Study of Semantics and Sentiment in ruGPT3large-Generated and Human-Written Movie Reviews
Authors:   HSE University Saint-Petersburg, Margolina Anastasia , Kolmogorova Anastasia
Published: February 2024

The paper describes the proposed strategy for evaluation controlled text generation with the sentiment as attribute. Our approach mainly consists of automatic sentiment analysis (ruBERT) and topic modelling (BERTopic), which are applied to a parallel corpus with artificially produced and human-written texts. The model for evaluation is fine-tuned on the parsed reviews from big Russian movie-related website ruGPT3Large with the sentiment as prompt. The results of the analysis demonstrate that the proposed methods can offer a more comprehensive understanding of the advantages and limitations in the context of semantics and sentiment. Additionally, the paper employs metrics such as BERTscore and self-BLEU to further evaluate the generated text. The proposed methodology provides a novel approach for evaluating the quality of generated text and may have implications for future studies in the field
The Typological constructicon database
Authors:   University of Hamburg, Muravyev Nikita , Gordeev Nikita ,   NRU HSE (Moscow), Makarchuk Ilya , Kukushkina Maria
Published: February 2024

The report introduces a new resource: the Typological Constructicon database. This resource contains an inventory of constructions of selected semantic fields in a number of languages of different areal and genetic affiliation. The constructions are labeled according to a number of semantic and morphosyntactic parameters and provided with a detailed description and illustrative examples.
Is it possible to make the Russian punctuation rules more explicit?
Authors:   Vinogradov Russian Language Institute of the Russian Academy of Sciences / Volkhonka 18/2, Moscow, Russia, Shmelev Alexei
Published: February 2024

This paper deals with some issues related to the Russian punctuation rules and their account in computer checkers and correctors (both “analytic” and “synthetic”). It also discusses variation of punctuation. The paper offers a critical assessment of reference books devoted to punctuation and makes special reference to certain verbs of propositional attitude and their parenthetical use (in particular, dumat’ ‘to think,’ videt’ ‘to see,’ and slyshat’ ‘to hear). It claims that the inherent characteristics of the verbs under consideration influence the punctuation, and therefore every verb deserves a detailed description (lexicographic portrait). In particular, videt’ and slyshat’ behave quite differently when used as parenthetical verbs. A step towards making the punctuation rules more explicit may consist in providing an index of words mentioned in the rules together with a subject index.
RUSSIAN PREDICATIVES AND FREQUENCY METRICS
Authors:   Pushkin State Russian Language Institute / Institute of Linguistics, Russian Academy of Science, Zimmerling Anton
Published: February 2024

This paper introduces five metrics for measuring the frequencies of dative predicatives in Russian.А dative predicative is a word or multiword expression licensing the dative-predicative-structure, where the semantic subject of the non-agreeing non-verbal predicate is marked by the dative case. I measure the frequencies of the predicatives in the contact position <-1;1> with the same-clause dative subject pronouns in 1Sg (m-metrics) and 3Sg (e-metrics). The m-metrics is applied for retrieving a list of dative predicatives from a corpus. I argue that for each large text collection there is a minimal m-value confirming that an item belongs to the core of the dative-predicative structure. The m/e score makes up the third metrics that shows whether an element is oriented towards the use in the 1 st person or not. Basing on the m-metrics, I retrieved 3 lists of predicatives in the subcorpus of 2000–2021 texts included in the Russian National Corpus. The A list includes 87 items with m  10, the B list includes 44 items with m  50, the C list includes 24 items with m  100. 72-79% of items in each list have an m/e value  1,25. A linguistic interpretation of this result is that for each list of dative predicatives it is true that the majority of its elements are autoreferential expressions oriented towards the use in the 1st person present indicative tense in the direct speech. The fourth metrics shows the total number of occurrences of a word or multiword expression in the corpus (N). I argue that the N score must be measured before POS tagging, and lemmatization. The fifth and the last metrics is the m/N score. The RNC data suggest an inverse correlation between the score of an item in the context specific for dative-predicative structures (m) and its overall frequency in the corpus (N). This effect is explained by the regular homonymy of high frequent predicatives with high frequent adverbials and parenthetical expressions.
THE ARTISTIC PHILOSOPHY OF K. G. PAUSTOVSKY
Authors:   Lugansk state Pedagogical University, Darenskii Vitalii
Published: February 2024

The article examines the artistic philosophy of K. G. Paustovsky, which means both the set of creative principles contained in the Golden Rose and other essays, and the basic semantic structures of his prose. The basis of K. G. Paustovsky’s poetics is defined as “artistic asceticism”, since the basis of Paustovsky’s artistic philosophy is the understanding of creativity as the transformation of being and the formation of personality. At the level of artistic form, this asceticism creates a classical style; at the level of content, it is a symbol of overcoming death through love. At the level of the model of human relationships, creativity is the science of meeting, mercy and forgiveness. The event of death becomes an artistic symbol of the fulfillment of truth. Catharsis is achieved by the reader through familiarization with the primordial goodness of being, overcoming tragedies in human relationships. Paustovsky’s representative texts are considered, demonstrating these principles at the level of the writer’s reflections and several plots of his stories.
DACHA TOPOS IN THE LIFE AND WORK OF K. G. PAUSTOVSKY
Authors:   A. M. Gorky Institute of World Literature of the Russian Academy of Sciences, Skorokhodov Maxim
Published: February 2024

The biography and work of K. G. Paustovsky provide rich material for revealing not only the features of dacha topos, but also the phenomenon of literary dacha - the place where writers live, the space where artistic works are created and dacha topos is creatively embodied. Paustovsky lived in dachas in Peredelkino, Solotcha, Stary Krym, Tarusa. When choosing a place for rest and work, he focused on the need to provide solitude, communication with interesting people, trips to the surroundings, if possible - fishing. Dacha life is reflected in many of the writer's works (The Meshcherskaya Side, The Golden Rose, The Black Sea, The Last Devil, The Golden Fox, The Stealing Cat, The Gift, Farewell to Summer, Cordon 273, The Empty Dacha, The Simple Man (About Konstantin Fedin), Ruvim Frayerman, Meetings with Gaidar, etc.) and in his letters. The article shows that for Paustovsky - both in his life and in his work - the traditions of Russian “estates house literature” are significant, and the occupation in the dacha and its surroundings largely coincides with those occupations that are characteristic of the inhabitants of Russian estates.
PHYTONIMICAL VOCABULARY IN MILITARY STORIES OF K. PAUSTOVSKY
Authors:   HE Far Eastern State Agrarian University, Filitova Olga
Published: February 2024

The article deals with the features of phytonymic vocabulary in several military stories of K. G. Paustovsky. The studied vocabulary occupies an exceptionally important place in the military works of Soviet writers, including Paustovsky. Despite the significance of the interpretation of phytonyms for an adequate understanding of the ideological content of the writer’s texts, this aspect of his work still remains little explored. The importance of phytonymic vocabulary is evidenced, in particular, by the fact that in the stories of Paustovsky wartime, the whole variety of phytonyms is used: the names of trees (birch, linden, willow, oak, etc.), herbs (chamomile, mint, nettle, etc.), parts of plants (leaf, branch), their communities (garden, grove, forest, etc.). The most prominent place in the works of the war years is given to the first and fourth groups. Analysis of phytonyms in military stories by Paustovsky allows us to conclude that their symbolism is connected with Slavic folk traditions, Christianity and European culture.
K. G. PAUSTOVSKY IN SCHOOL: CONVENTIONAL AND MODERN APPROACH
Authors:   Moscow Pedagogical State University, Antipova Alla
Published: February 2024

This article summarizes the learning experience of K. G. Paustovsky works at different levels of school literary education (primary and secondary school). Analysis of literature programs, learning aids and guidelines, guidance papers, research articles, and teaching practices helped to establish a scope of works of K. G. Paustovsky recommended for study and extracurricular reading. It also helped to define approaches to the analysis of these works and main methods and techniques of working with the text, and to discover the educational potential of various forms of extracurricular activity used to cultivate interest in the writer’s work. The author identifies main tutorial problems associated with understanding the writer’s artistic world in a classroom or extracurricular literature classes, and proposes a planning option for classes studying the works of K. G. Paustovsky, years 5 to 11, based on the curriculum of literature textbooks on the subject edited by V. F. Chertov. The curriculum was developed with reference to the accumulated educational experience and the results of modern research on the writer’s work.
EVALUATION OF WATER POLLUTION STATUS OF TRIYUGA RIVER IN UDAYAPUR DISTRICT, NEPAL
Authors: Das Bishnu Dev , Pradhan Sonu , Sardar Amrita , Paudel Niroj , Mishra Ranjan Kumar
Published: February 2024

The present investigation has been conducted to assess the status of physiochemical and microbiological parameters to understand the present scenario of water quality at Triyuga River water at Belaka municipality of Udayapur district, Nepal. The temperature ranged from 180C to 200C, the TDS value ranged from 89 mg/L to 112 mg/L and were below the WHO guideline value of 1200 mg/L, the pH values of the surface water sources in the present study were found to be alkaline ranging above from 7.6 to 7.9 were found within the range of WHO guideline value of 6.5-8.5. Similarly the values of dissolved oxygen ranged from 6.4 mg/L to 10.4 mg/L and were above the WHO guideline value of 5 mg/L, the bicarbonate (HCO3) value ranged from 105 mg/L to 125 mg/L and were below the WHO guideline value of 125-350 mg/L, the values of Nitrate ranged from 3 mg/L to 5 mg/L and were below the WHO guideline of 50 mg/L, the values of Nitrite ranged from 0.3 mg/L to 0.5 mg/L, the value of Ammonium ranged from 0 mg/L to 0.3 mg/L, the values of Iron ranged from 1 mg/L to 1.5 mg/L and were above the WHO guideline of 0.3 mg/L and the phosphate was not detected in all the three different sites of surface water samples. The fecal coliform was found to be positive in all the samples and the value of fecal coliform recorded was 15, 15 and 21 MPN/100ml in Site I, II and III respectively.
An Exploratory Criterion Validation of Three Meaning-Recall Vocabulary Test Item Formats
Authors: Stoeckel Tim , Ishii Tomoko
Published: February 2024

In an upcoming coverage-comprehension study, we plan to assess learners’ meaning-recall knowledge of words as they occur in the study’s reading passage. As several meaning-recall test formats exist, the purpose of this small-scale study (N = 10) was to determine which of three formats was most similar to a criterion interview regarding mean score and the consistency of correct/incorrect classifications (match rate, k = 30).In Test 1, the prompt consisted of only the target item, and a written translation of its meaning was elicited. In Test 2, the prompt was a short sentence in which a target item was highlighted, and a written translation of only that target item was requested. In Test 3, the prompt was the same sentence as in Test 2, but the target item was unhighlighted, and participants were requested to translate the entire sentence. Finally, in the criterion interview, participants were asked to demonstrate their understanding of the target items in the same prompt sentences as in Tests 2–3. The results indicated that Test 3 produced a mean score and match rate most similar to the interview, followed by Test 2, with Test 1 being the least similar. The paper discusses several factors explaining differences in test performance that were explored during the interview
Integridad ecológica en un bosque bajo producción maderable del centro de México
Authors: Rendón-Pérez Martha Azucena , Hernández-de la Rosa Patricia , Reyes-Hernández Valentín José , Velázquez-Martínez Alejandro , Alcántara-Carbajal José Luis
Published: February 2024

La integridad ecológica (IE) es la propiedad de un ecosistema para soportar y mantener una comunidad de organismos cuya composición, diversidad y organización funcional sea comparable con un hábitat natural de la región. Este concepto es útil para conocer el grado de conservación de un ecosistema, por lo que es de interés en la gestión forestal. El objetivo fue desarrollar y aplicar un Índice de Integridad Ecológica (IIE) en una zona de bosque templado con aprovechamiento maderable. El lugar presentó cuatro asociaciones vegetales: tres bajo aprovechamiento maderable (Pinus montezumae, P. patula y P. pseudostrobus) y una correspondiente a un área de conservación (Pinus-Quercus). Para calcular el índice, se evaluó la estructura, composición y función del bosque a través de 20 indicadores, correspondientes a tres atributos ecológicos: paisaje, vegetación y suelo. Se establecieron cuatro categorías posibles: excelente, buena, regular y baja. El mayor valor del IIE se obtuvo en el área de conservación en la categoría excelente, mientras que en las asociaciones bajo aprovechamiento, la de P. patula se clasificó como excelente y las de P. montezumae y P. pseudostrobus se clasificaron como buenas. En el área bajo aprovechamiento se requiere observación e intervención mínima para mantener y mejorar la IE. El IIE permitió caracterizar las asociaciones bajo manejo, además de identificar los indicadores que requieren de intervención o mayor investigación para mantener la IE. Se generó así una línea base del conocimiento de la IE en el área de estudio, que puede ser útil para su gestión.
Innovative Pedagogical Approaches to the Periodic Table for Freshman Chemistry Student at the State University of Padang
Authors: Ismail Irfan Ananda , Mawardi Mawardi , Suryani Okta , Insani Munadia , Mulyanti Mulyanti
Published: February 2024

This study developed innovative approaches to chemistry education for first-year students at the State University of Padang in the era of Industry 4.0. The research utilized the Plomp development model to formulate a method based on the Flipped Classroom paradigm with a Guided Inquiry Syntax. The resulting content was validated by five Chemistry lecturers at UNP, indicating its innovative and pertinent material depth. The content's practicality achieved a value of 90%, suggesting its ease of application and relevance for students. The systematic presentation enhances students' understanding of the Periodic System. This research offers valid and practical solutions to challenges in chemistry education, using creative content as an innovative strategy to provide a teaching tool that enhances students' understanding of complex concepts. The study's practicality stage demonstrates that the developed content is easy to apply and relevant for students, making it a valuable addition to chemistry education
OBESIDADE E DIABETES
Authors:   Instituto do Coração (InCor). Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP, Pinheiro Xerfan Corso Mariana , Hayashida Mizuta Marjorie ,   Instituto do Coração (InCor). Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP). Unidade Clínica de Lípides,   Instituto do Coração (InCor). Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP). Centro de Medicina de Precisão em Cardiologia, Cordeiro Juliani Fabiana ,   Instituto do Coração (InCor). Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP). Laboratório de Metabolismo e Lípides, Zorzanelli Rocha Viviane ,   Instituto do Coração (InCor). Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP). Unidade Clínica de Lípides.
Published: February 2024

O excesso de peso, resultante de fatores genéticos, comportamentais e socioeconômicos, tornou-se uma preocupação global, afetando mais de 1,9 bilhão de indivíduos, com uma prevalência que triplicou desde 1975. Paralelamente, o diabetes tipo 2 segue a mesma trajetória preocupante. Globalmente, estima-se que 463 milhões de adultos vivam com diabetes, número que deve aumentar para 578 milhões até 2030. O índice de massa corpórea (IMC) é uma ferramenta valiosa para avaliar a obesidade em escala populacional, mas apresenta limitações. Estudos recentes destacam a adiposidade abdominal como indicador independente de morbimortalidade, especialmente quando combinada ao IMC elevado. A obesidade é um fator central na gênese de inúmeras desordens, incluindo a resistência à insulina, diabetes tipo 2, doenças cardiovasculares, distúrbios imunológicos e a doença hepática gordurosa. Além de armazenar energia, o tecido adiposo é um órgão ativo, desempenhando papel central na regulação metabólica através da secreção de uma gama de mediadores. O ganho de peso induz mudanças no seu perfil secretório, particularmente aumento da produção de mediadores infla-matórios, desencadeando inflamação sistêmica e disfunção metabólica. Macrófagos ativados contribuem para esse processo, evidenciando a interconexão entre obesidade, inflamação e resistência à insulina. A perda de peso sustentada, alcançada por meio de mudanças no estilo de vida, atividade física e dieta equilibrada, é fundamental. No entanto, a cirurgia bariátrica e terapias medicamentosas, como o uso de análogos do GLP-1, mostram-se promissoras e necessárias em significativa parcela dos casos. O tratamento da obesidade não apenas melhora a saúde metabólica, mas também impacta positivamente o controle do diabetes