bluuebunny/crossref_metadata_2025 huggingface dataset:
Phenotypic and metabolomic characteristics of mouse models of metabolic associated steatohepatitis
Authors: Yang Cian-Ru , Lin Wen-Jen , Shen Pei-Chun , Liao Pei-Yin , Dai Yuan-Chang , Hung Yao-Ching , Lai Hsueh‐Chou , Mehmood Shiraz , Cheng Wei-Chung , Ma Wen-Lung
Published: January 2024

Background

Metabolic associated steatohepatitis (MASH) is metabolic disease that may progress to cirrhosis and hepatocellular carcinoma. Mouse models of diet-induced MASH, which is characterized by the high levels of fats, sugars, and cholesterol in diets, are commonly used in research. However, mouse models accurately reflecting the progression of MASH in humans remain to be established. Studies have explored the potential use of serological metabolites as biomarkers of MASH severity in relation to human MASH.

Methods

We performed a comparative analysis of three mouse models of diet-induced MASH in terms of phenotypic and metabolomic characteristics; MASH was induced using different diets: a high-fat diet; a Western diet; and a high-fat, high-cholesterol diet. Liver cirrhosis was diagnosed using standard clinical approaches (e.g., METAVIR score, hyaluronan level, and collagen deposition level). Mouse serum samples were subjected to nuclear magnetic resonance spectroscopy–based metabolomic profiling followed by bioinformatic analyses. Metabolomic analysis of a retrospective cohort of patients with hepatocellular carcinoma was performed; the corresponding cirrhosis scores were also evaluated.

Results

Using clinically relevant quantitative diagnostic methods, the severity of MASH was evaluated. Regarding metabolomics, the number of lipoprotein metabolites increased with both diet and MASH progression. Notably, the levels of very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) significantly increased with fibrosis progression. During the development of diet-induced MASH in mice, the strongest upregulation of expression was noted for VLDL receptor. Metabolomic analysis of a retrospective cohort of patients with cirrhosis indicated lipoproteins (e.g., VLDL and LDL) as predominant biomarkers of cirrhosis.

Conclusions

Our findings provide insight into the pathophysiology and metabolomics of experimental MASH and its relevance to human MASH. The observed upregulation of lipoprotein expression reveals a feedforward mechanism for MASH development that may be targeted for the development of noninvasive diagnosis.
Latent Dirichlet Allocation (LDA) topic models for Space Syntax studies on spatial experience
Authors: Lee Ju Hyun , Ostwald Michael J.
Published: January 2024

Spatial experience has been extensively researched in various fields, with Space Syntax being one of the most widely used methodologies. Multiple Space Syntax techniques have been developed and used to quantitively examine the relationship between spatial configuration and human experience. However, due to the heterogeneity of syntactic measures and experiential issues in the built environment, a systematic review of socio-spatial topics has yet to be developed for Space Syntax research. In response to this knowledge gap, this article employs an ‘intelligent’ method to classify and systematically review topics in Space Syntax studies on spatial experience. Specifically, after identifying 66 articles using the ‘Preferred Reporting Items for Systematic reviews and Meta-Analyses’ (PRISMA) framework, this research develops generative probabilistic topic models to classify the articles using the Latent Dirichlet Allocation (LDA) method. As a result, this research automatically generates three architectural topics from the collected literature data (A1. Wayfinding behaviour, A2. Interactive accessibility, and A3. Healthcare design) and three urban topics (U1. Pedestrian movement, U2. Park accessibility, and U3. Cognitive city). Thereafter it qualitatively examines the implications of the data and its LDA classification. This article concludes with an examination of the limitations of both the methods and the results. Along with demonstrating a methodological innovation (combining PRISMA with LDA), this research identifies critical socio-spatial concepts and examines the complexity of Space Syntax applications. In this way, this research contributes to future Space Syntax research that empirically investigates the relationships between syntactic and experiential variables in architectural and urban spaces. The findings support a detailed discussion about research gaps in the literature and future research directions.
Prediction of flight departure delays caused by weather conditions adopting data-driven approaches
Authors: Kim Seongeun , Park Eunil
Published: January 2024

In this study, we utilize data-driven approaches to predict flight departure delays. The growing demand for air travel is outpacing the capacity and infrastructure available to support it. In addition, abnormal weather patterns caused by climate change contribute to the frequent occurrence of flight delays. In light of the extensive network of international flights covering vast distances across continents and oceans, the importance of forecasting flight delays over extended time periods becomes increasingly evident. Existing research has predominantly concentrated on short-term predictions, prompting our study to specifically address this aspect. We collected datasets spanning over 10 years from three different airports such as ICN airport in South Korea, JFK and MDW airport in the United States, capturing flight information at six different time intervals (2, 4, 8, 16, 24, and 48 h) prior to flight departure. The datasets comprise 1,569,879 instances for ICN, 773,347 for JFK, and 404,507 for MDW, respectively. We employed a range of machine learning and deep learning approaches, including Decision Tree, Random Forest, Support Vector Machine, K-nearest neighbors, Logistic Regression, Extreme Gradient Boosting, and Long Short-Term Memory, to predict flight delays. Our models achieved accuracy rates of 0.749 for ICN airport, 0.852 for JFK airport, and 0.785 for MDW airport in 2-h predictions. Furthermore, for 48-h predictions, our models achieved accuracy rates of 0.748 for ICN airport, 0.846 for JFK airport, and 0.772 for MDW airport based on our experimental results. Consequently, we have successfully validated the accuracy of flight delay predictions for longer time frames. The implications and future research directions derived from these findings are also discussed.
Development of quality indicators for palliative care in intensive care units and pilot testing them via electronic medical record review
Authors: Tanaka Yuta , Masukawa Kento , Sakuramoto Hideaki , Kato Akane , Ishigami Yuichiro , Tatsuno Junko , Ito Kaori , Kizawa Yoshiyuki , Miyashita Mitsunori
Published: January 2024

Background

Patients in intensive care units (ICUs) often require quality palliative care for relief from various types of suffering. To achieve quality palliative care, specific goals need to be identified, measured, and reported. The present study aimed to develop quality indicators (QIs) for palliative care in ICUs, based on a systematic review and modified Delphi method, and test their feasibility by reviewing electronic medical record (EMR) data.

Methods

The current study was performed in two phases: the development of QIs using the modified Delphi method, and pilot-testing the quality of palliative care in ICUs based on EMR review. The pilot test included 262 patients admitted to the general or emergency ICU at a university hospital from January 1, 2019, to June 30, 2019.

Results

A 28-item QI set for palliative care in ICUs was developed based on the consensus of 16 experts. The Delphi process resulted in low measurability ratings for two items: "Assessment of the patient's psychological distress" and "Assessment of the patient's spiritual and cultural practices." However, these items were determined to be important for quality care from the perspective of holistic assessment of distress and were adopted in the final version of the QI set. While the pilot test results indicated the feasibility of the developed QIs, they suggested that the frequency of care performance varied, and certain aspects of palliative care in ICUs needed to be improved, namely (1) regular pain assessment, (2) identification of the patient's advance directive and advance care planning for treatment, (3) conducting an interdisciplinary family conference on palliative care, and (4) assessment of psychological distress of family members.

Conclusions

The QI set, developed using the modified Delphi method and tested using EMR data, provided a tool for assessing the quality of palliative care in ICUs. In the two ICUs considered in this study, aspects of the palliative care process with a low performance frequency were identified, and further national surveys were recommended. It is necessary to conduct ongoing surveys at more facilities to improve the quality of palliative care in ICUs.
Low plasma vitamin D is associated with increased 28-day mortality and worse clinical outcomes in critically ill patients
Authors: Sistanian Fatemeh , Sedaghat Alireza , Badpeyma Mohaddeseh , Rezaiyan Majid Khadem , Moghaddam Ahmad Bagheri , Ranjbar Golnaz , Arabi Mostafa , Bagherniya Mohammad , Norouzy Abdolreza
Published: January 2024

Background & objective

Patients in the intensive care unit have a high prevalence of vitamin D deficiency (VDD). In the present study, clinical outcomes in the ICU were analyzed with vitamin D status.

Materials and methods

In this prospective, multicenter study, sampling was conducted on seven ICUs in three hospitals. Within the first 24 h of ICU admission, patient’s serum vitamin D levels were measured, and their disease severity was monitored using the scores of acute physiologic assessment and chronic health evaluation II (APACHE II), sequential organ failure assessment (SOFA), and the modified Nutrition Risk in Critically ill (mNUTRIC) score.

Results

A total of 236 patients were enrolled in this study, of which 163 (69.1%) had lower vitamin D levels than 20 ng/ml upon ICU admission. The patients with VDD had higher APACHE II scores)P = 0.02), SOFA scores (P < 0.001), and mNUTRIC scores (P = 0.01). Patients with sufficient levels of vitamin D (> 30 ng/ml) had a shorter stay at ICU (P < 0.001). VDD was independently associated with 28-day mortality (OR: 4.83; 95% CI: 1.63–14.27; P = 0.004).

Conclusion

The data showed that VDD was common among the critically ill and was related to a more severe course of illness and a higher mortality rate.
Hand grip strength as a proposed new vital sign of health: a narrative review of evidences
Authors: Vaishya Raju , Misra Anoop , Vaish Abhishek , Ursino Nicola , D’Ambrosi Riccardo
Published: January 2024

Hand grip strength (HGS) serves as a fundamental metric in assessing muscle function and overall physical capability and is particularly relevant to the ageing population. HGS holds an important connection to the concept of sarcopenia, which encompasses the age-related decline in muscle mass, strength, and function. It has also been reported to indicate the health of an individual. We reviewed the interplay between HGS and various health parameters, including morbidity and mortality, by carrying out a literature search on PubMed, Scopus and Google Scholar between 10 and 30 August 2023, to identify the relevant papers on the relationship between health and HGS. We used several keywords like ‘hand grip strength’, ‘muscle strength, ‘sarcopenia’, ‘osteosarcopenia’, ‘health biomarker’, ‘osteoporosis’, and ‘frailty’, to derive the appropriate literature for this review. This review has shown that the HGS can be measured reliably with a hand-held dynamometer. The cut-off values are different in various populations. It is lower in Asians, women, less educated and privileged, and those involved in sedentary work. Several diseases have shown a correlation with low HGS, e.g., Type 2 diabetes, cardiovascular disease, stroke, chronic kidney and liver disease, some cancers, sarcopenia and fragility fractures. The low HSG is also associated with increased hospitalization, nutritional status, overall mortality and quality of life. We believe that there is adequate evidence to show that HGS stands as an important biomarker of health. Its utility extends to the identification of diverse health issues and its potential as a new vital sign throughout the lifespan.
Faster determination of an initial velocity model for full-waveform inversion based on simulated annealing
Authors: Mendes Rafael , Kaelin Bruno , Martínez-Sansigre Alejo , Barbosa Valmir C. , Bentes Cristiana , Amorim Claudio L.
Published: January 2024

Full-waveform inversion (FWI) is a prominent method commonly used to create detailed velocity models of the subsurface. However, because it relies on gradient methods, it suffers from the limitation of getting trapped in local minima. To avoid this problem, FWI needs to start from an initial velocity model that lies in the same region of convexity as the global minimum. Global optimization methods, such as simulated annealing, can be used to find such an initial velocity model. However, the iterative process of simulated annealing entails high computational cost, first because of the large number of iterations needed to explore the variables space, and second because of the large number of simulations needed to adjust the simulation parameters. Although the first issue is a common concern of previous work, the second issue is usually neglected, relying on trial and error. We introduce an approach to tackle the issues and then apply it within a simulated annealing framework we create. Our experiments using the Marmousi data yielded promising results when compared with previous work. We find that our approach almost eliminated the computational effort to fine-tune several simulation parameters. In addition, the number of iterations needed to explore the variables space is reduced by two orders of magnitude. FWI is able to find a detailed velocity model with high quality when using the initial velocity model generated by the method.
Modeling multisource multifrequency acoustic wavefields by a multiscale Fourier feature physics-informed neural network with adaptive activation functions
Authors: Chai Xintao , Gu Zhiyuan , Long Hang , Liu Shaoyong , Yang Taihui , Wang Lei , Zhan Fenglin , Sun Xiaodong , Cao Wenjun
Published: January 2024

Recently, the physics-informed neural network (PINN) was adopted to solve partial differential equation (PDE)-based forward and inverse problems. Compared to numerical differentiation, a PINN calculates derivatives by mesh-free automatic differentiation without dispersion artifacts. The Fourier feature PINN was applied to solve the frequency-domain acoustic wave equation to model multifrequency scattered wavefields. Although solving for scattered wavefields avoids the source singularity problem, it has drawbacks (e.g., requiring an analytic formula for computing the background wavefield, which only exists for the wave equation for simple models). We evaluated an approach for modeling multisource multifrequency acoustic wavefields using a multiscale Fourier feature mapping (MFFM) PINN with adaptive activations, directly solving for full wavefields instead of scattered wavefields and naturally avoiding the drawbacks of solving the scattered wave equation. For the MFFM, we explored the determination of the maximum and number of Fourier scales. Our inputs to the MFFM were only the spatial coordinates of the subsurface model; this result is lower than that of previous work (improving the efficiency of the PINN while maintaining its accuracy). Because the activation function is extremely important for a PINN, we use an existing technique and adapt it to a new architecture and develop an adaptive amplitude-scaled and phase-shifted sine activation function, which performs the best among the studied activation functions. Experiments show that the MFFM, adaptive activation, an appropriate learning rate, a linearly shrinking NN, and transfer learning greatly improve the convergence rate, accuracy, and efficiency of the PINN for simulating multisource multifrequency wavefields, laying the foundation for applying a PINN to wave equation-based inversion and imaging. We shared our codes, data, and results via a public repository.
Charakterystyka bilansu energetycznego oraz przewag konkurencyjnych rynku energii krajów Unii Europejskiej z Europy Środkowo-Wschodniej
Authors: Nowak Ewa , Przepióra Paweł
Published: January 2024

Gospodarowanie paliwami i energią w Europie przechodzi znaczącą transformację w kierunku nowych modeli wytwarzania energii, a odbiorcy są zachęcani do zmiany swoich zachowań w kierunku oszczędzania i większej efektywności energetycznej. Struktura bilansu energetycznego państwa ma znaczenie dla bezpieczeństwa energetycznego i wpływa również na zapewnienie odpowiedniego poziomu ochrony środowiska oraz zahamowanie negatywnych zmian klimatycznych. Bezpieczeństwo energetyczne i poprawa efektywności energetycznej to jeden ze strategicznych celów Unii Europejskiej, ponieważ wywiera wpływ na bezpieczeństwo energetyczne krajów członkowskich, konkurencyjność ich gospodarek oraz poprawę warunków życia ich mieszkańców. Celem artykułu jest poznanie zróżnicowania struktury bilansu energetycznego państw Europy Środkowo-Wschodniej, które są członkami Unii Europejskiej. Do tej grupy należy 11 krajów: Bułgaria, Chorwacja, Czechy, Estonia, Litwa, Łotwa, Polska, Rumunia, Słowacja, Słowenia oraz Węgry. Wykorzystano dostępne bazy danych Eurostatu i Światowej Rady Energetycznej (World Energy Council) na 2021 r. Analiza ukierunkowana jest na przedstawienie możliwości wykorzystania sztucznych sieci neuronowych Kohonena do wyodrębnienia państw podobnych z uwagi na strukturę bilansu energii pod względem nośników energii (ropa naftowa, gaz ziemny, stałe paliwa kopalne, energia jądrowa, odnawialne źródła energii). Wartość tego podejścia polega na tym, że algorytm Kohonena na podstawie wag neuronów i po analizie samoorganizującej się mapy uznaje sąsiedztwo obiektów (państw) za element ważny w badaniach regionalizacji. Indeks Potrójnego Energetycznego Dylematu – IPED (Word Energy Trilemma Index – WETI) pokazuje sytuację energetyczną krajów w odniesieniu do: poziomu bezpieczeństwa energetycznego, równości energetycznej i zrównoważonego rozwoju środowiska. Pozwala on na porównanie ich ze sobą pod kątem bezpieczeństwa energetycznego, konkurencyjności gospodarczej i ochrony środowiska naturalnego. Analiza regresji liniowej wielozmiennej określiła rzeczywisty wpływ zmiennych niezależnych (ropa naftowa, gaz ziemny, stałe paliwa kopalne, energia jądrowa, odnawialne źródła energii) na zmienną zależną IPED, który jest międzynarodowym miernikiem do porównań transformacji energetycznej kraju w kontekście nowych uwarunkowań środowiskowych i geoekonomicznych. Przy wykorzystaniu metody regresji wskazano, że znaczącą determinantą efektywności transformacji energetycznej krajów jest wysoki udział energii odnawialnej w strukturze bilansu energetycznego.
Transition from entrepreneurship education to entrepreneurial intention: A cross-cultural effect
Authors: Amofah Kwaku , Gameli Dziwornu Michael , Rachwał Tomasz , Saladrigues Ramon , Agyarko-Fosu Fred
Published: January 2024

Through a cross-cultural examination, this study aims to analyse a move from the field of entrepreneurship education (EE) to entrepreneurial intention (EI). Specifically, we carried out mediation (perceived behavioural control (PBC) and attitude towards entrepreneurship (ATE)) and moderation (gender and country) analysis. The study surveyed 546 Polish and Spanish university students and used a multi-group analysis to test the model across groups. The results reveal that attitude and PBC partially mediate the effect of EE on EI. Moreover, the results show that the model is consistent in both countries. The study contributes to the comparative international entrepreneurship literature on how the theory of planned behaviour (TPB) applies in different contexts and implications it has for this field of study.
Zróżnicowanie kierunków przemian pasażerskiej regionalnej kolei w Polsce po 1989 r.
Authors: Soczówka Andrzej , Ochociński Krzysztof
Published: January 2024

Przedmiotem badań były przemiany oferty pasażerskich pociągów regionalnych w Polsce po 1989 r. Przeanalizowano dynamikę i kierunki przemian oferty w cyklach 5-letnich w podziale na 16 współczesnych województw. Celem badań była identyfikacja prawidłowości i różnic dotyczących kierunków przemian regionalnej oferty kolejowej w poszczególnych województwach po 1989 r. Procedura badawcza polegała na stworzeniu dwóch odrębnych baz danych – bazy linii kolejowych w środowisku GIS oraz bazy połączeń kolejowych. W badaniach wykazano, w jaki sposób czynniki infrastrukturalne wpływały na długość sieci obsługiwanej przez pociągi regionalne i wielkość pracy eksploatacyjnej, jakie było zróżnicowanie tempa i kierunków przemian oferty połączeń regionalnych w poszczególnych województwach. Zwrócono uwagę na odcinki sieci z niefunkcjonalną ofertą przewozową. Zbadano wpływ sposobu organizacji kolejowych regionalnych przewozów pasażerskich w aspekcie wyboru przewoźników kolejowych na rozwój lub regres oferty przewozowej. Badania wykazały, że po kryzysie z okresu lat 90. XX w. i na początku XXI w. w większości województw następowała stopniowa poprawa oferty przewozowej, zwłaszcza na obszarach aglomeracyjnych. W większości przypadków usamorządowienie kolei miało pozytywny wpływ na ofertę przewozów regionalnych, chociaż znacząco pogorszyło ofertę na granicach województw. Rozwojowi sieci kolejowych połączeń regionalnych i poprawie oferty przewozowej sprzyja model powierzenia części lub większości przewozów samorządowemu przewoźnikowi, ale nie jest to czynnik decydujący.
Análise do impacto da covid-19 no acionamento de seguros auto
Authors: Dalla Dea Prado Matheus , Bomgiovani Cazzari Roberto
Published: January 2024

Com a chegada da pandemia da COVID-19, o mercado segurador sofreu múltiplos impactos, e dentro desse campo, o seguro auto foi amplamente atingido. O presente trabalho teve como objetivo identificar e entender quais os impactos causados pela COVID-19 no acionamento dos seguros, considerando tanto uma dimensão de frequência quanto de severidade. Foram analisadas as regiões do estado de São Paulo, com dados segregados por sexo e faixa etária. O estudo comparou os dados do semestre pré-pandemia (segundo semestre de 2019) com os do primeiro semestre de 2020, a fim de capturar os primeiros impactos no mercado de seguros auto, consequentes da chegada da COVID-19. As principais conclusões consistiram na diminuição de reclamações do referido seguro e no aumento da severidade dessas reclamações, resultando em um reajuste positivo nos valores de prêmio do seguro.
Η πορεία προς τη γνώση σύμφωνα με τον Άγιο Συμεών το Νέο Θεολόγο
Authors: Χριστόπουλος Αθανάσιος
Published: January 2024

Οι σύγχρονοι ρυθμοί της ζωής δημιουργούν μια κενότητα στον άνθρωπο, ο οποίος ενώ φαινομενικά τα έχει όλα, στην ουσία δεν έχει τίποτα, δεν έχει τη γνώση ακόμα και αν αποκτήσει όσα υλικά αγαθά μπορεί για να καλύψει τις εφήμερες – ψευτο-ανάγκες του, πάλι μέσα του θα αισθάνεται, ότι κάτι του λείπει, ένα ατελείωτο κενό, γιατί δεν έχει κάνει καμία κίνηση, καμία υπέρβαση για να αποκτήσει την αληθινή γνώση. Ο ανθρώπινος νους πρέπει να αλλάξει, να τραπεί, να μετατραπεί και να αλλοιωθεί με την καλή έννοια, να ανοίξει τις πνευματικές του αντένες για να μπορέσει να αντιληφθεί την γνώση του Συμεών. Αυτή η γνώση είναι που θα τον οδηγήσει στην ευδαιμονία στην ολοκλήρωση και στη Θέωση, για τον άγιο Συμεών υπήρξε πορεία ζωής, για τον κάθε άνθρωπο που μελετάει τον άγιο Συμεών αυτή η πορεία προς τη γνώση είναι εφικτή και μπορεί να γίνει πραγματικότητα, ξεκινώντας από τον τρόπο που ζει σε αυτό τον κόσμο αρκεί να ακολουθήσει τον φιλοσοφικό - νοητό και λογικό - ερευνητικό αλλά και θεολογικό τρόπο σκέψης του. Η ανάπτυξη της εργασίας εκτείνεται σε τρία βασικά μέρη, τα οποία έχουν αλληλένδετη εξάρτηση το ένα από το άλλο, στο πρώτο μέρος γίνεται μια σύντομη αναφορά στον όρο «γνώση». Κάνοντας μια σύντομη ιστορική αναδρομή θα φτάσουμε στην εποχή του Συμεώνος, θα διασαφηνιστεί η έννοια της γνώσεως καθώς επίσης και ποια είναι τα κοινά της σημεία με την Πλατωνική Φιλοσοφία και τους Στωικούς, αλλά και με έναν νεότερο φιλόσοφο τον Γκαμπριέλ Μαρσέλ, ο οποίος πλησιάζει τη σκέψη του αγίου Συμεών. Στο δεύτερο μέρος θα αναπτυχθούν οι θέσεις του αγίου Συμεώνος ως προς τη Δημιουργία: τον άνθρωπο και τον κόσμο, το σώμα, την ψυχή και πως ο άνθρωπος ξέφυγε από το ρόλο του και έπεσε στην αμαρτία, μια κατάσταση που ισοδυναμεί για τον Συμεών με την «αγνωσία» δηλαδή την απώλεια της γνώσης. Στη συνέχεια, εξετάζεται ποια είναι τα αποτελέσματα για τον άνθρωπο, η κατάσταση της φθοράς – «αγνωσίας». Το τρίτο μέρος αναφέρεται στην πορεία (στάδια), δηλαδή στην πορεία για υπέρβαση της φθοράς, που μπορεί να κάνει κάθε άνθρωπος με σκοπό να αποκτήσει τη γνώση. Τί διαφορά έχει η γνώση για τον άγιο Συμεών, τί είναι ο φωτισμός και η μέθεξη του Θείου Φωτός, από ποια στάδια και προϋποθέσεις διέρχεται ο άνθρωπος για να επιτύχει την επίγνωση, δηλαδή την πνευματική του προκοπή, ποια είναι η «τροπή των όντων», με ποιο τρόπο ο άνθρωπος «αλλάζει» μεταμορφώνεται και μετουσιώνεται ο νους από «ανθρωποειδή» σε «θεοειδή». Στο τελευταίο μέρος καταγράφονται τα συμπεράσματα αλλά αναδεικνύεται και η προσωπικότητα του Συμεώνος του νέου Θεολόγου, μέσα από τον ποιητικό του λόγο (Παράρτημα), εκεί όπου ο Άγιος συναντάει τον Ποιητή και αντίστροφα. Στην κατακλείδα της εργασίας θα περιληφθούν εν συντομία λόγοι του αγίου Συμεώνος σε ποιητική μορφή, κείμενα επιλεγμένα με οκτασύλλαβο στίχο που περικλείουν φιλοσοφικούς στοχασμούς με θεολογική διαύγεια και αποτελούν υψηλό επίπεδο διανόησης, της Βυζαντινής Φιλοσοφίας.
Μορφές ισοδυναμίας χώρων και αλγεβρών τελεστών
Authors: Παπαπέτρος Ευάγγελος
Published: January 2024

Ο στόχος αυτής της διατριβής είναι η παρουσίαση και μελέτη μορφών ισοδυναμίας μεταξύ χώρων και αλγεβρών τελεστών. Ασχολούμαστε με ισοδυναμίες τύπου Morita που αντικαθιστούν την έννοια του ισομορφισμού με μια ασθενέστερη αλλά πιο ευέλικτη έννοια. Αυτή μας επιτρέπει να ταυτίζουμε άλγεβρες με ισοδύναμες κατηγορίες αναπαραστάσεων γενικεύοντας το πλαίσιο και τις έννοιες που όρισε αρχικά ο Rieffel για C*-άλγεβρες και von Neumann άλγεβρες, οι Blecher, Muhly και Paulsen για μη-αυτοσυζυγείς άλγεβρες τελεστών και αργότερα ο Ελευθεράκης για δυϊκές (και μη) άλγεβρες τελεστών και για χώρους τελεστών. Στο πρώτο μέρος της εργασίας αυτής ορίζουμε τη Δ-Morita και τη σΔ-Morita ισοδυναμία για άλγεβρες τελεστών και χώρους τελεστών. Χαρακτηρίζουμε τα Δ-ζεύγη και τα σΔ-ζεύγη μέσω των κατηγοριών των αριστερών προτύπων τους και αποδεικνύουμε ότι σΔ-Morita ισοδύναμοι χώροι τελεστών είναι ευσταθώς ισόμορφοι και αντίστροφα. Στη συνέχεια μελετούμε μια ειδική κατηγορία προτύπων υπεράνω αλγεβρών τελεστών, τα rigged modules, που αποτελούν γενίκευση της έννοιας των Hilbert modules όπως αυτή αναπτύχθηκε από τους Rieffel και Paschke. Χαρακτηρίζουμε τα rigged modules υπεράνω μιας άλγεβρας τελεστών Α που είναι ορθογώνια συμπληρώματα στην C_{oo}(A) και χρησιμοποιούμε αυτή την κατηγορία προτύπων για να ορίσουμε ισοδυναμίες τύπου Morita μεταξύ rigged modules εξετάζοντας πότε αυτές επάγουν ευσταθείς ισομορφισμούς και μεταξύ των προτύπων και μεταξύ των αλγεβρών τελεστών όπου τα πρότυπα δρουν. Μελετούμε επίσης ισοδυναμίες τύπου Morita για w*-rigged modules υπό το πρίσμα του πότε αυτές επιφέρουν ευσταθή ισομορφισμό. Στο δεύτερο μέρος της εργασίας μας, μελετούμε το ακόμα ανοιχτό πρόβλημα της ομοιότητας μορφισμών C*-αλγεβρών που εισήχθη από τον Kadison: Δοθείσης μιας μοναδιαίας C*-άλγεβρας A και ενός μοναδιαίου φραγμένου μορφισμού u: A -> B(H), όπου H είναι χώρος Hilbert, υπάρχει αντιστρέψιμος τελεστής S που ανήκει στον B(H) ώστε η απεικόνιση π(x)=S^{-1} u(x) S να ορίζει *-μορφισμό της A; Παρουσιάζουμε κάποια κριτήρια για το πότε το πρόβλημα αυτό έχει θετική απάντηση και αποδεικνύουμε ότι είναι ισοδύναμο με ένα άλλο ανοικτό πρόβλημα της Θεωρίας των C*-αλγεβρών: Κάθε υπερανακλαστική von Neumann άλγεβρα που δρα σε διαχωρίσιμο χώρο Hilbert είναι πλήρως υπερανακλαστική. Το αντίστροφο είναι αληθές. Επίσης, χρησιμοποιώντας την έννοια της υπερανακλαστικότητας των von Neumann αλγεβρών και αποδεικνύοντας σχετικά κριτήρια υπερανακλαστικότητας, δίνουμε νέα παραδείγματα von Neumann αλγεβρών που ικανοποιούν την εικασία της ομοιότητας. Τα τρία από τα τέσσερα άρθρα, των οποίων τα αποτελέσματα παρουσιάζουμε στην εργασία αυτή, έχουν ήδη δημοσιευθεί στα διεθνή περιοδικά "Integral Equations and Operator Theory (IEOT)", "New York Journal of Mathematics (NYJM)" και "Advances in Operator Theory (AIOT)". Tο 4ο έχει δημοσιευθεί στο arxiv και έχει σταλεί σε διεθνές περιοδικό προς δημοσίευση.
Personal and professional development through sustainable partnerships in education Serbian experiences from the I-TAP-PD Erasmus+ project
Authors: Koruga Nikola , Đokić Dunja , Krsmanović Tasić Sanja
Published: January 2024

The aim of this research is to evaluate how the partnership between teachers and artists was built in the context of Serbia. In conducting it, we sought answers to the following research question: What was the role of I-TAP-PD in the personal and professional development of teachers and artists in Serbia? It is based on the phenomenological theory of reflection in action. Research participants include three teacher-artist pairs. The residencies were delivered between August 2021 and June 2022. The data was collected with pre-residency questionnaires, reflective journals, classroom observation, post-residency group interviews. All qualitative data was analysed using thematic analysis. The results show that artists and teachers, in terms of sustainable partnership in researched practices in Serbia, identified the understanding of the “other“ as the most important aspect of the process of learning and teaching. In this endeavour, professionals developed high levels of empathy and their self-esteem notably increased.
Πρωτοσέλιδα
Authors: Eranistes Eranistes
Published: January 2024

No abstract
Le Grec littéral: Blason de la noblesse Phanariote émergente
Authors: Bouchard Jacques
Published: January 2024

Η λόγια ελληνική γλώσσα: έμβλημα της αναδυόμενης τάξης των Φαναριωτών στις Παραδουνάβιες Ηγεμονίες

Κατά τη διάρκεια του 17ου αιώνα βοεβόδες, βογιάροι και λόγιοι της Μολδοβλαχίας αντικατέστησαν τη σλαβονική με την ελληνική γλώσσα στους τομείς της διοίκησης και της παιδείας. Η καθομιλουμένη ελληνική έγινε κοινή λαλιά στις Παραδουνάβιες Ηγεμονίες. Για να επιδείξει την υπεροχή της απέναντι στην τοπική κοινωνία η αναδυόμενη τάξη των Φαναριωτών προέβαλε ως σύμβολο της ευγενικής κωνσταντινουπολίτικης καταγωγής και ισχύος της μια γλαφυρή εκδοχή της αρχαίας ελληνικής γλώσσας. Υποδείγματα τέτοιου ύφους και γραφής είναι τα κείμενα των Μαυροκορδάτων, Αλέξανδρου και Νικόλαου.
Δύο Κυδωνιάτες στο Παρίσι στα 1819-1820
Authors: Lappas Costas
Published: January 2024

Deux Cydoniens à Paris en 1819-1820. Commentaires sur un poème de P. G. Rodios

Panaghiotis G. Rodios (1789-1851), étudiant en médecine à Paris quelques années avant la Révolution grecque, a écrit un poème avec lequel il faisait ses adieux à son ami Constantinos Dimou, qui quittait Paris pour sa patrie, Cydonies d’Asie Mineure. Le poème est imprimé en deux feuilles sans mention de lieu ni d’année de publication; mais d’après son contenu nous concluons qu’il a été publié à Paris en 1820. Exemple typique de la poésie grecque de l’époque, il nous donne des informations utiles sur Constantinos Dimou et son ami Patroclos, ainsi que sur la vie quotidienne des jeunes Grecs à Paris. En combinant ces informations avec des témoignages provenant d’autres sources, nous sommes conduits à la conclusion que Constantinos Dimou est l’imprimeur bien connu Constantinos Dimidis (1792-1869), qui était arrivé de Cydonies à Paris en novembre 1819 avec son compatriote Patroclοs Paraskevas. Dimidis apprend la typographie à l’imprimerie Didot et l’armurerie chez l’arquebusier de Paris Fatou. Paraskevas apprend la fabrication du papier dans une papeterie près de Versailles. À Paris, Dimidis et Patroclos avaient des relations étroites avec Panaghiotis Rodios, ancien élève de l’École desCydonies, qui était arrivé à Paris en 1817 pour des études supérieures. Dimidis est resté à Paris un an. À la fin de 1820 il partit pour Cydonies et c’est à cette occasion que fut écrit le poème de Rodios. À son retour, Dimidis travailla d’abord comme armurier à Cydonies et plus tard comme imprimeur à Hydra, Nauplie et ailleurs. À l’été 1821 Patroclos et Rodiosquittèrent Paris pour le Péloponnèse révolté; le premier y perdit sa vie prématurément et le second a fait à la suite une carrière militaire remarquable.
Μνείες Φιλελλήνων και σημασιοδοτήσεις του Φιλελληνισμού στην Ελλάδα κατά τον 19ο αιώνα
Authors: Sfoini Alexandra
Published: January 2024

Mentions des philhellènes et significations du philhellénisme en Grèce auXIXe siècle

L’étude aborde la question de la mémoire du philhellénisme en Grèce au XIXe siècle, lorsque l’Europe, en particulier l’Allemagne, s’est tournée vers l’Est et notamment vers la Turquie. Les références sporadiques repérées dans la presse périodique concernent des philhellènes bien connus, tels que Jean-Gabriel Eynard, Georges Canning, Santorre di Santarosa,George Gordon Byron, Percy Shelley, François-René de Chateaubriand, Alexandre Puchkine. Certains des philhellènes parmi les moins connus ont été honorés durant les premières années de l’État grec. Beaucoup d’entre eux ont été mentionnés dans des listes établies par le général Makrygiannis, et plus tard par le colonel français Auguste Hilarion Touret et l’officier suisse Henri Fornèsy. Dans ces références, la principale importance du philhellénisme est liée à la participation à la lutte pour l’indépendance de la Grèce, pour laquelle les philhellènes sont gratifiés et déclarés citoyens de l’hellénisme. Le concept de philhellénisme se transforme en fonction de l’époque et des aspirations de chaque utilisateur, et son champ sémantique s’étend de l’amitié méditerranéenne qui unit les peuples, du libéralisme et de la rhétorique anti-tyrannique, aux idées démocratiques et au socialisme. Au milieu du siècle, une élaboration du concept, par Georgios Tertsetis et Stefanos Koumanoudis, le relie à la gloire ancestrale, aux lumières de l’Évangile et à la destinée de la nation grecque dont le but est de civiliser l’humanité. La qualité qui perpétue le philhellénisme est identifiée au passé de l’âge classique revendiqué par l’hellénisme moderne : c’est la signification du philhellénisme qui connaît la plus grande résilience.
Το Άσμα του Κολοκοτρώνη, 1822
Authors: Politis Alexis
Published: January 2024

No abstract
Plastid genome of Passiflora tripartita var. mollissima (poro-poro) from Huánuco, Peru
Authors: Aliaga Flavio , Zapata-Cruz Mario , Valverde-Zavaleta Silvia Ana
Published: January 2024

Passiflora tripartita var. mollissima, known locally as poro-poro, is an important native fruit used in traditional Peruvian medicine with relevant agro-industrial and pharmaceutical potential for its antioxidant capacity for human health. However, to date, only a few genetic data are available, which limits exploring its genetic diversity and developing new genetic studies for its improvement. We report the poro-poro plastid genome to expand the knowledge of its molecular markers, evolutionary studies, molecular pathways, and conservation genetics. The complete chloroplast (cp) genome is 163,451 bp in length with a typical quadripartite structure, containing a large single-copy region of 85,525 bp and a small single-copy region of 13,518 bp, separated by a pair of inverted repeat regions (IR) of 32,204 bp, and the overall GC content was 36.87%. This cp genome contains 128 genes (110 genes were unique and 18 genes were found duplicated in each IR region), including 84 protein-coding genes, 36 transfer RNA-coding genes, eight ribosomal RNA-coding genes, and 13 genes with introns (11 genes with one intron and two genes with two introns). The inverted repeat region boundaries among species were similar in organization, gene order, and content, with a few revisions. The phylogenetic tree reconstructed based on single-copy orthologous genes and maximum likelihood analysis demonstrates poro-poro is most closely related to Passiflora menispermifolia and Passiflora oerstedii. In summary, our study constitutes a valuable resource for studying molecular evolution, phylogenetics, and domestication. It also provides a powerful foundation for conservation genetics research and plant breeding programs. To our knowledge, this is the first report on the plastid genome of Passiflora tripartita var. mollissima from Peru.
How to deal with pain in the emergency department - pain management review
Authors: Beutler Katarzyna , Bijata Bartosz , Burek Dawid , Paszkowska Aleksandra , Kujawa Aleksandra , Matuszewska Urszula , Nykowska Aleksandra
Published: January 2024

One of the primary health issues bringing patients to hospital emergency rooms is pain. It is often treated inadequately. Doctors working in the emergency department have the option of using a number of drugs for analgesia. The three main groups include non-steroidal anti-inflammatory drugs, non-opioid analgesics and opioid analgesics. In order to properly exploit their potential, it is necessary to properly classify the pain, know the basic action of the available drugs, choose the right dose, and know how to combine drugs from different groups to achieve balanced analgesia. By acting in this way, the patient in the hospital emergency department will be properly provided with medication, and this will have a positive effect on his overall health.
Zinner's syndrome and retroperitoneal fibrosis: an unknown association
Authors: Morante-Ruiz Miguel , Tornero-Romero Fernando , Palacios-Miras Carmelo , Lage-Estébanez Fernado Vicente , Cantero-Del Olmo Lara , Martínez-Alemany Iris , Martínez-Andrés Juan
Published: January 2024

We report the case of a 24-year-old male presenting with obstructive renal failure, characterised by imaging evidence of a cystic lesion contingent upon the seminal vesicle and concurrent renal agenesis. Initial management involved urinary diversion, followed by outpatient monitoring and subsequent recurrence. Subsequent diagnostic assessments led to the identification of Zinner's syndrome, accompanied by retroperitoneal fibrosis. We present the clinical course, diagnostic methodology and the efficacious implementation of medical-surgical therapeutic interventions, yielding favourable outcomes.
Queer designers: Experimentações não-conformativas na geração de uma rede dissidente
Authors: Santana Cunha Aura Celeste , Mota Borges Lucas
Published: January 2024

Este estudo apresenta o processo de formação de uma rede de designers dissidentes em gênero e sexualidade, a fim de experimentar e delinear práticas contra-normativas no design. Foram realizadas oficinas com grupo focal em que discursos e saberes de sujeitos dissidentes em gênero e sexualidade apoiassem o projeto. Enquanto escrita, a argumentação crítica de teoria queer e história do design foram somadas a outras reflexões evocadas pelos participantes do grupo formado, o que apoia este texto enquanto um fluxo de pensamento coletivo de caráter político e de descrição de um processo experimental. Sobretudo, foram apontadas formas de provocar debates e instigar produção subjetiva no campo do design, levando em consideração as questões que envolvem corpos não-conformativos.Busca-se, até o momento de publicação deste trabalho, uma continuidade das estratégias experimentadas para apoiar um processo aberto e não estático de pensar e fazer design voltado para o queer.
Championing nurse-led services for cardiology patients
Authors: Pottle Alison
Published: January 2024

Alison Pottle, Consultant Nurse, Cardiology, Harefield Hospital, London ( A.Pottle@rbht.nhs.uk ), was the winner of the Silver Award in the Cardiovascular Nurse of the Year Category in the BJN Awards 2023
What is known from the existing literature about how sleep is measured in HIV care? A scoping review
Authors: Bourne Kathryn , Croston Michelle , Hurt Emily , Galbraith Nichola , Hayter Mark
Published: January 2024

The HIV care landscape has significantly altered over the past 30 years with advances in HIV medical treatment. Despite these medical advances, people living with HIV experience a significant number of issues that affect their health-related quality of life, including sleep. Although poor sleep quality is common, there remains a lack of understanding of how to identify sleep issues in order to improve outcomes for people living with HIV. A scoping review of three databases as well as the grey literature yielded 2932 articles, of which 60 met the inclusion criteria. The following themes were identified: range of methods used to assess sleep, self-reported sleep measures and objective measures of sleep. The review found that a number of different measures of sleep were used within the research, the most commonly used being the Pittsburgh Sleep Quality Index. Due to the variety of approaches being used to measure sleep (n=18) there was a lack of consistency in what aspects of sleep were being explored, and in many cases why the measure of sleep was chosen. Furthermore, there was a lack of meaningful clinical recommendations as to how these findings could be used to improve outcomes for people living with HIV.
How does intersectionality impact the quality of healthcare services for Black women living with HIV?
Authors: Hannon-Walker Imogen , McLuskey John
Published: January 2024

Women with HIV are affected more than men by intersecting discriminations. For Black women, additional discrimination can have a detrimental effect on their HIV care. An extended literature review of primary research studies was undertaken to explore the issues and the impact of intersectionality on Black women with HIV. Electronic databases were searched for studies published since antiretroviral treatment became recognised to be effective, and eight studies met detailed inclusion and exclusion criteria. Critical appraisal led to the identification of three themes: discrimination; stigmatisation; and racism. The findings suggest that while Black women with HIV reported barriers to health care because of intersectionality, older women who felt confident in their self-identity were more able to cope with issues around this. Knowledge of the factors affecting these women will enable health professionals to deliver person-centred care.
Connecting mind and mouth
Authors: Littel Teddie
Published: January 2024

Teddie Littel discusses the health connections between the mouth and body.
Keeping out of harm's way
Authors: Varney Nicky
Published: January 2024

Nicky Varney discusses the importance of automated and validated infection control protocols.
Keeping record
Authors: Wake Charlotte
Published: January 2024

Charlotte Wake outlines the importance of clear record keeping in the practice.

Aim

To gain a greater understanding of record keeping.

Objectives

Reflect on what the GDC standards state about record keeping. Review what is included in a patient record. Determine the role of the nurse in relation to record keeping.
Ray-tracing model of a perfect lens compliant with Fermat’s principle: the Cardinal Lens
Authors: Wilde Jeffrey P.
Published: January 2024

When using ray tracing for optical system design, it is often the case that the
designer would like to implement simplified versions of one or more
compound lens groups. This could be the case during initial layout
when idealized versions of such compound lenses are needed or, perhaps
alternatively, to mimic a well-corrected commercially available lens
for which the prescription details are unavailable. One option is to
use a paraxial thin lens as a proxy for the actual lens group, but
doing so will yield a layout that is not consistent with Fermat’s
principle or the Abbe sine condition. For example, a paraxial lens
version of a compound microscope objective typically produces the
wrong numerical aperture for a given entrance pupil diameter, and vice
versa. A better option is to use a lens model that provides perfect
imaging for a specified paraxial magnification and obeys Fermat’s
principle. A variant of the model can yield a perfect Fourier
transform lens. In addition, it is desirable to implement an idealized
thick lens in which the principal planes are separated by a
user-specified distance. This paper presents such a model, referred to
as the Cardinal Lens, with implementation in Zemax OpticStudio via a
user-defined surface.
Modified CFBG-based approach for chromatic dispersion compensation in high speed DWDM links
Authors: G. R. Sreeragi , Vijayakumar N. , R. Pradeep
Published: January 2024

Chromatic dispersion (CD) is a major concern in high speed fiber optics communication systems. This work presents an efficient optical compensation technique with reduced complexity to mitigate CD effects in single mode fiber (SMF) at high data rates. The proposed method includes a post-dispersion mitigation system using a single linear chirped fiber Bragg grating (CFBG) with tanh apodization. Here, various parameters of CFBG, such as grating length, effective refractive index, and apodization function, are optimized to achieve effective CD compensation. Then, the system is extended to a 16-channel WDM link with each channel carrying data at 25 Gbps over 100 km. The simulation results show that the proposed model enhances the system performance while minimizing overall system complexity. The proposed system is also compatible with the prevailing fiber optics networks. The results are consistent with the findings published in recent studies.
High-robustness autofocusing method in the microscope with laser-based arrayed spots
Authors: Wang Zhihao , Zhang Xin , Chen Xindong , Miao Liang , Kang Ke , Mo Chenggang
Published: January 2024

Accurate and rapid autofocus technology plays a crucial role in various fields, including automatic optical inspection technology, bio-chips scanning, and semiconductor manufacturing. The current photoelectric autofocus methods have limitations because of detecting the focal plane solely at the center of the microscope field of view. In the application of Stereo-seq the risk of autofocus errors will be increased, which have reduced the robustness of the system, like when the surface of the tested samples are wrinkling and inconsistent thickness, or the detection spot is at the edge of the sample. To enhance the robustness of the autofocus system and mitigate the constraints of the photoelectric autofocus methods, the laser-based arrayed spots photoelectric autofocus method has been proposed. To achieve the uniform light splitting, a 2D-Dammann grating is incorporated into the optical path of the autofocus system, resulting in the formation of an n × n arrayed spots on the surface of the sample. Through experimental verification, it has been demonstrated that this method can achieve the autofocus range of ±100μm and the autofocus accuracy of ±1/4 DOF when applied to a microscope equipped with a 10× objective lens, thereby satisfying the requirements for microscopic focusing. The arrayed light autofocus method devised in this study presents what we believe is a novel research concept for active autofocus detection and holds significant application value.
Complex Master-Slave Enhanced Optical Coherence Microscopy
Authors: Camard Julien , Marques Manuel , Canedo-Ribeiro Carla , Silvestri Giuseppe , Ellis Peter , Robinson Gary , Chávez-Badiola Alejandro , Griffin Darran , Bradu Adrian , Podoleanu Adrian
Published: January 2024

We present an instrument designed to facilitate localization and high-resolution, Optical Coherence Microscopy (OCM) imaging of small biological samples immersed in a medium several orders of magnitude greater in volume. A modified turret-equipped microscope stand was inserted into the sample arm of a Spectral Domain Optical Coherence Microscopy (SD-OCM) system. The instrument enabled swift change of imaging objectives through the incorporation of Complex Master-Slave Interferometry (CMSI), providing tolerance to dispersion for any objective through the acquisition of a few (≥2) calibration spectra. We demonstrate the instrument's ability to localize and image samples by providing examples of its application to optical phantoms and to a porcine oocyte immersed in a biological culture medium.