bluuebunny/crossref_metadata_2025 huggingface dataset:
A Learning-based Data Placement Framework for Low Latency in Data Center Networks
Authors: Navale Vinay S , Jane Chetan , B Anvita , B Kalyan , A Satvik
Published: August 2023

Abstract: The challenge of achieving low-latency data services has become increasingly crucial for data center applications. In modern distributed storage systems, efficient data placement plays a vital role in minimizing data movement delays, thereby significantly reducing service latency. While previous solutions for data placement have often relied on pre-assumed data request distributions or traced analysis, the dynamic nature of network conditions and evolving user request patterns poses a complex online decision-making challenge. Traditional static model-based approaches are limited in their ability to cope with such dynamic system dynamics. To address these challenges and consider both data movement and analytical latency, we introduce a novel framework named DataBot+. This framework leverages reinforcement learning techniques to autonomously learn optimal data placement policies. DataBot+ employs neural networks that are trained using a modified version of Q-learning. The input to these networks comprises real-time data flow measurements, while the output is a value function that estimates the imminent future latency. To ensure timely decision-making, DataBot+ is designed with a two-fold asynchronous architecture, consisting of production and training components. This separation guarantees that the training process does not introduce additional overhead to the handling of data flows. Our approach is validated through extensive evaluations using real-world traces, which convincingly demonstrate the efficacy of our proposed design.
Unveiling Stock Market Trends Implementing LSTM and KNN Algorithms
Authors: T Rasagna , Charan Kankanala L S V S Nagamani
Published: August 2023

Abstract: The objective of this study is to enhance and assess the efficacy of Long Short Term Memory (LSTM) and k-Nearest Neighbors (KNN) algorithms in the context of predicting stock prices. This study entails the acquisition of historical data from credible sources pertaining to pricing, as well as other significant variables such trade volume and market mood. Subsequently, the gathered data undergoes a process of cleansing, preprocessing, and refining to ensure its compatibility with the training model. Subsequently, we constructed a forecasting model utilizing Long Short-Term Memory (LSTM) and another forecasting model employing K-Nearest Neighbors (KNN).
Analisis Kelayakan Finansial Usaha Ternak Ayam Ras Petelur di Desa Ponggok Kabupaten Blitar
Authors: Saraswati Annisa , Kusuma Hendra , Hidayat Riyanto Wahyu
Published: August 2023

Penelitian ini dilakukan dengan tujuan untuk mengetahui kelayakan usaha ternak ayam ras petelur serta strategi pengembangan usaha ternak ayam ras petelur di Desa Ponggok Kabupaten Blitar. Metode penelitian yang digunakan dalam penelitian ini adalah metode Kualitatif dan untuk menganalisis kelayakan menggunakan 2 aspek utama studi kelayakan yaitu aspek keungan menggunakan Teknik Analisis Finansial PP, NPV, IRR, B/C Ratio dan ROI dan analisis SWOT untuk menganalisis strategi pengembangan usaha. Teknik pengumpulan data dalam penelitian ini ialah menggunakan Teknik wawancara dan dokumentasi terhadap 2 responden yaitu pemilik usaha ternak ayam ras petelur. Berdasarkan hasil penelitian analisis finansial usaha ternak ayam ras petelur di Desa Ponggok sepenuhnya layak dijalankan,dikarenakan terdapat 3 hasil perhitungan yaitu PP, IRR, dan B/C Ratio milik ibu Sri Andayani yang menunjukkan hasil layak dan 2 perhitungan NPV dan ROI menunjukkan hasil tidak layak. Sedangkan usaha milik bapak Supriyanto sepenuhnya layak untuk dijalankan karena terdapat hasil 3 perhitungan yaitu PP, IRR), B/C Ratio), yang menunjukkan usaha tersebut layak, sedangkan 2 perhitungan NPV, dan ROI menghasilkan nilai yang negative sehingga dikatakan tidak layak
Analisis Pendapatan Jasa Persewaan Tenda Pesta di Desa Klampok Kabupaten Malang
Authors: Ananda Febriansyah
Published: August 2023

Penelitian ini dilakukan dengan tujuan menganalisis pendapatan usaha dan analisis SWOT pada bidang sektor jasa persewaan Tenda Pesta di Desa Klampok Kabupaten Malang Jenis penelitian yang digunakan adalah penelitian kuantitatif deskriptif dengan menganalisis pendapatan dan analisis SWOT (Strenght, Weakness, Opportunity, Threat) usaha Persewaan Tenda Pesta di Desa Klampok Kabupaten Malang. Analisis dalam penelitian ini dilakukan dengan menganalisis pendapatan, R/C rasio, SWOT dan matriks SWOT. Hasil penelitian menunjukkan pendapatan yang diperoleh oleh jasa Persewaan Tenda Pesta dapat terbilang sangat banyak karena penerimaan dan biaya yang dikeluarkan memiliki selisih yaitu sebesar Rp. 13.871.389. Dari analisis R/C rasionya sebesar 1,95 yang lebih besar dari 1. Nilai efisiensi usaha 1,95 berarti bahwa setiap 1 rupiah biaya yang dikeluarkan oleh usaha Persewaan Tenda dan Alat-Alat Pesta akan didapatkan penerimaan 1,95 kali, dari hasil perhitungan IFAS (Internal Factors Analysis Summary) dan EFAS (External Factors Analysis Summary) bahwa kesempatan usaha Persewaan Tenda dan Alat-Alat Pesta lebih besar daripada ancaman, sehingga strategiyang sesuai adalah strategi S-O.
Inovasi Kreatif Untuk Meningkatkan Pengembangan Usaha Jajan Cimoet
Authors: Boedirochminarni Arfida , Juliati Ratih , Jatmiko Rohmat
Published: August 2023

Penelitian ini membahas kontribusi UMKM kreatif di Desa Klampok Kasri, khususnya dalam usaha jajan cimoet. Desa tersebut memiliki kelompok usaha makanan seperti warung makan dan pembuatan kue. Tujuan penelitian ini adalah mengungkap manfaat positif pemberdayaan kearifan lokal melalui pengembangan usaha jajan cimoet yang dikelola oleh Ibu Umiati.Metode penelitian yang digunakan adalah wawancara, kuesioner, dokumentasi, dan observasi. Hasil penelitian menunjukkan kontribusi signifikan usaha jajan cimoet dalam pemberdayaan kearifan lokal dan peningkatan konsumsi rumah tangga. Namun, usaha ini menghadapi tantangan dalam packaging, pemasaran online, peningkatan mutu, pengolahan, serta pembukuan sederhana.Untuk mengatasi tantangan tersebut, dilakukan pelatihan teknologi pengemasan yang menarik loyalitas pelanggan serta pembukuan sederhana yang mendukung pembiayaan perbankan. Penelitian ini memberikan rekomendasi untuk mendukung UMKM kreatif dalam mengembangkan usaha jajan cimoet dengan memanfaatkan media sosial sebagai sarana pemasaran
Perancangan Sistem Pakar Gejala Penyakit Pada Burung dan Kucing Menggunakan Metode Forward Chaining Berbasis Android
Authors: Rahmi Imanda  , Fauziyyah Damar Kharisma
Published: August 2023

This study discusses the problems experienced by pet owners, especially cats and birds in dealing with diseases experienced by their pets. Based on the results of the questionnaires that have been conducted, as many as 74.3% of pet owners have minimal knowledge about what types of diseases can attack their pets (cats and birds), 80% of the distance traveled to the vet clinic is quite far, 60% of the existing veterinarians are still relatively minimal, and pet owners have their own busy lives and activities. This study aims to create an expert system in the form of an android-based application, which can assist pet owners in obtaining information about the results of disease symptoms in pets, what kind of treatment can be given, drug suggestions for the disease. The method for tracing the solution used is the Forward Chainig method, where the analysis is carried out after the information is given to then produce conclusions in the form of the name of the disease. The kar system application is made using the Java and PHP programming languages. The expert system application created in this study can help pet owners, especially cats and birds, in getting information about the symptoms of diseases that attack their pets. This is based on the results of testing the beta test results of all the features in the application running well and a success rate of 100%, and based on the results of the effectiveness test of the acceptance of this expert system application, it is very good at 89.35%.
Arbuscular mycorrhizal characterization associated with Uncaria guianensis and Uncaria tomentosa in Amazonian soils
Authors: Garzón Lina Paola , Peña-Venegas Clara Patricia
Published: August 2023

There are some plant species with cultural and economic importance in the Amazon, such as Uncaria guianensis and U. tomentosa, both commonly named “cat's claw”. Since these species grow in soils with low levels of organic matter and nutrients, both depend on arbuscular mycorrhizae to grow. The information about arbuscular mycorrhizal fungi communities for U. tomentosa is limited and there is no current research on U. guianensis. Therefore, this research provides additional information on the arbuscular mycorrhizal fungi communities associated with Uncaria species in Amazonian soils. Both the percentage of root colonization and the influence of the edaphic composition in the two species were determined. Also, the richness and diversity of arbuscular mycorrhizal fungi were assessed using the spore isolation method and also, through the molecular analysis of virtual taxa. In addition, the difference between the soils was analyzed. Although U. guianensis grows in both Oxisols and Alluvial Entisols and U. tomentosa is restricted to Oxisols, sporulation of AM and root colonization does not respond significantly to variations in soil chemical properties. Additionally, 72 virtual taxa were identified for Uncaria species (53 U. tomentosa and 19 U. guianensis) and the relative abundance of arbuscular mycorrhizal fungi was higher in roots of Uncaria species than in soils. The arbuscular mycorrhizal fungi community that colonizes the roots of Uncaria species indicates that these species behave as wild species; therefore, the ex-situ propagation of the species in agricultural systems could be less successful than forest enrichment.
O legado de Francisco de Oliveira: memórias, ideias e reflexões de uma trajetória
Authors: Moreira Allan Barbosa
Published: August 2023

Resenha do livro Francisco de Oliveira: questões, diálogos, depoimentos, organizado por Carlos Alberto Bello (FFLCH/USP), Cibele Saliba Rizek (Fapesp/USP), Joana Barros (IEA/USP) e Leonardo Mello e Silva (FFLCH/USP).
Extraction of A Four Rooted Maxillary Third Molars: A Case Series of Rare Occurrence.
Authors: Mukram Ali Fareedi , Somili Alanood Mansour , Shabi Afnan Yahya , Ustad Farheena , Gadah Thuraya Saleh , Suleman Ghazala , Mohammed Mahzari Rashed Hussain , Ali Areshi Raneem Abdullah
Published: August 2023

It is uncommon to find maxillary molars with four roots, known to have three roots (two buccal and one palatal); it might also havethree, sometimes fused roots. Maxillary third molars have a wide range of morphologies, making it challenging clinically and difficult to distinguishthem radiographically. Given the proximity of the maxillary tuberosity and the floor of the maxillary antrum, the presence of an accessory rootmay complicate a rather straightforward exodontia of the maxillary third molar. We present a case series of three maxillary third molarextractions. The extracted tooth had four roots, an unusual variation in root shape. This case series focuses on morphological changes in theroots of maxillary third molars that are difficult to detect on routine radiographs. Also, this case series highlights the potential for extensivemorphological variation in the maxillary third molar, which could make a simple extraction challenging. To avoid difficulties, cautious extractionmaneuvering is required. Hence it is advisable to prepare for the possibility of an accessory root on a maxillary molar in endodontic and oralsurgical clinical practice to prevent difficulties after surgery. The lesson to be learned from this case series is there can be a possibility for an extraroot in the maxillary third molar, and the dentist must always be alert.Keywords: , , , ,
Investigation results of deformation matrixes for the CS-42 coordinate system
Authors: Mareev A.V.
Published: August 2023

For transition from the coordinate system CS-42 to the Earth-centered, Earth-fixed SCS-2011, correct transformation models are required. Such a model is a non-linear transformation of coordinate systems via the grid shift method. The Data Grid of transformation parameters from CS-42, CS-95 to SCS-2011 were developed in 2016 at the Federal Scientific and Technical Center of Geodesy, Cartography and Spatial Data Infrastructure and are called deformation matrices of CS-95 (CS-42). The accuracy of coordinate transformation is declared as 10 cm for areas with a high density of state geodetic network points. The author presents the results of the deformation matrix analysis for the Republic of Bashkortostan. Evaluation of errors in it due to violation of the mesh irregularity is presented. Recommendations for improving the model are given
Construction of digital terrain models based on remote sensing data of inaccessible continental areas
Authors: Astapovich A.V. , Zhbanov K.K.
Published: August 2023

The method of combining digital terrain models based on the results of photogrammetric processing optoelectronic stereo photographs and interferometric one of radar images developed in the view of the least squares principle is substantiated in the article. The necessary formulas for assessing the impact of systematic errors in jointly handled data sets are given. As a result of analyzing the systematic errors influence in setting the beginning of the height calculation in alternative models on the values of the combined relief model parameters, it is shown that it is impossible to estimate and completely exclude systematic errors of the desired characteristics of the combined relief model without involving additional measurement information. The methodology of the approach to the suppression of the mentioned mistakes in determining the required data is theoretically justified with the necessary mathematical expressions for the implementation of the stages of the proposed techniques based on a comparison of the height matrices obtained through the least squares method and the materials of space laser altimeters
O faroeste em John Ford e Glauber Rocha: a verdade e o mito da imagem
Authors: Costa Rodrigo Cazes
Published: August 2023

Este artigo visa estudar como o retrato do gênero faroeste, nos filmes O homem que matou o facínora, de John Ford e Deus e o diabo na terra do sol, de Glauber Rocha, pode questionar a verdade, no sentido iluminista, teleológico, que uma imagem carrega, ou pretende carregar. Utilizo como apoio para minha reflexão os livros sobre cinema de Gilles Deleuze, Imagem-tempo e Imagem-movimento.
Observações sobre o tempo e a memória em Cidadão Kane
Authors: Silva Odair José Moreira da
Published: August 2023

A memória e o interesse pela exposição temporal que a fundamenta são um dos recursos que torna o cinema uma arte do tempo por excelência. Tomando como premissa de trabalho os conceitos de localização temporal, debreagem e embreagem, oriundos da semiótica francesa, o que se pretende aqui é verificar como o filme em questão opera com as categorias de tempo e a memória em sua diegese.
O Escritor: uma “máquina de produzir desordem”
Authors: Teixeira Claudio Alexandre de Barros
Published: August 2023

O Escritor: uma “máquina de produzir desordem” tem como objetivo estudar o romance visual de Ana Hatherly, composto entre 1969 e 1972, que apresenta afinidades estéticas com as vanguardas históricas e com as tradições barroca e maneirista, e em especial com os labirintos (ou textos visuais) do século XVII.
Heliogábalus
Authors: Maravalhas Junior Nelson
Published: August 2023

Este artigo busca analisar e categorizar um sujeito que circunda certo espaço na cidade de Brasília e realiza certos atos sui generis. O conceito trabalhado é o da Art Brut/Outsider Art, aqui utilizado ao (aparentemente psicótico) sujeito estudado, com matizações entre os gêneros tradicionais da escultura e da performance.
METODOLOGIA DA PRÁTICA DO CAMINHAR
Authors: Rodrigues Laís , Fiorin Evandro
Published: August 2023

Frequentemente caminhamos com o propósito de ir de um lugar a outro, sem a devida atenção ao meio do percurso, ao que está à nossa frente. A estética e a beleza passam despercebidas pelos olhares apressados e dão lugar aos mapas mentais previamente traçados, criados para obter uma execução perfeita do nosso objetivo: chegar. Chegar sem desvios e novas rotas. Fazemos isso constantemente, olhamos os lugares como zonas desconhecidas, zonas as quais não pertencemos e o comportamento de cada uma delas depende somente de nós. Nosso objetivo é traçar um caminho a ser percorridos das possíveis relações com a cidade, que posso promover um novo olhar a quem escolhe ver até onde os pés o farão chegar.
TEATRO NO CONTEXTO DA DIVULGAÇÃO CIENTÍFICA:
Authors: Almeida Carla , Hamilton Wanda
Published: August 2023

As iniciativas de divulgação científica que mesclam ciência e teatro proliferam em várias partes do mundo, inclusive no Brasil. No entanto, a produção acadêmica sobre o tema ainda é jovem, escassa e frágil, de modo que ainda se conhece pouco suas características e sua recepção entre diferentes públicos. Isto torna difícil compreendê-las em toda a sua riqueza e complexidade e saber como exatamente o teatro tem contribuído para o diálogo entre ciência e sociedade. A partir de uma imersão na prática e na pesquisa sobre o tema, fazemos neste ensaio uma reflexão crítica sobre o teatro no contexto da divulgação científica.
ARTES E CIÊNCIAS PARA VOAR... A CRIAÇÃO DE UMA OLIMPÍADA TRANSDISCIPLINAR
Authors: Lopes Thelma
Published: August 2023

As relações entre Artes e Ciências vêm constituindo objeto de pesquisas elaboradas por estudiosos com trajetórias acadêmicas diversas, evidenciando importantes questões: Como essas relações se concretizam na prática? Como repercutem no diálogo com a sociedade? Para quê aproximar dois campos do conhecimento aparentemente tão distantes entre si? Neste artigo pretendemos estabelecer reflexões seminais sobre tais indagações a partir da realização da “I Olimpíada de Ciência e Arte da Fundação Cecierj”.
Glutathione and Oxidized Low-Density Lipoprotein as Biomarkers of Oxidative Stress in Essential Hypertension
Authors:   Department of Physiology, Dow University of Health Sciences, Karachi, Sindh-Pakistan, Sahito Falak Sehar , Imtiaz Fauzia ,   Department of Biochemistry, Dow University of Health Sciences, Karachi, Sindh-Pakistan, Qamar Ambreen ,   Department of Physiology, Dow University of Health Sciences, Karachi, Sindh-Pakistan, Bhatty Shaheen ,   Department of Medicine, Dow University of Health Sciences, Karachi, Sindh-Pakistan, Waseem Hira Fatima ,   School of Public Health, Dow University of Health Sciences, Karachi, Sindh-Pakistan
Published: August 2023

OBJECTIVE: This study aimed to compare the serum levels of Glutathione and Oxidized Low-Density Lipoprotein in early hypertensive and normotensive subjects and to evaluate the diagnostic accuracy of these biomarkers for detecting oxidative stress in essential hypertension. METHODOLOGY: An analytical cross-sectional study was conducted at Civil (Dr. Ruth K.M. Pfau) Hospital Karachi from July 2020 to March 2021 after approval from the ethical committee. After informed consent, the serum oxidized low-density lipoprotein and glutathione levels were measured with ELISA's help in 40 normotensive and 40 early hypertensive participants. The results were analyzed by SPSS 21, keeping a significant p-value at <0.05. RESULTS: The median levels of Oxidized Low-Density Lipoprotein were higher in hypertensive than in normotensive (i.e. 31.47 ng/ml vs. 15.27 ng/ml). The median levels of glutathione were also raised in hypertensive compared with normotensive(i.e. 15.69 ng/ml vs. 4.46 ng/ml). The differences were significant (p-value <0.001). Both markers showed adequate diagnostic accuracy, sensitivity and specificity to detect oxidative stress in early hypertension. CONCLUSION: Oxidized Low-Density Lipoproteins are raised in early hypertension, endorsing the detrimental role of oxidative stress, while the levels of glutathione are increased to compensate for and combat increased oxidative stress in early hypertension. These biomarkers can be utilized clinically to discern the burden of oxidative stress in early hypertension. KEYWORDS: Essential hypertension, Glutathione, Oxidized low-density lipoprotein, Oxidative stress, Reactive oxygen species
CEO Overconfidence and Corporate Overseas M&A: The Case of Techcent Environment Company
Authors:   Asian Trade Association, Meng Xingchen
Published: August 2023

Purpose – In recent years, overseas M&As have become an important way for enterprises to invest and expand. Yet, most overseas deals are not successful. Behavioral finance research attributes the failure of overseas M&A to the irrational cognition of corporate decision-makers: that is, overconfidence. This study focuses on exploring the relationship between CEO overconfidence and overseas M&A, and clarifying the impact of CEO overconfidence on the motivation, payment method, and corporate performance of overseas M&A. Design/Methodology/Approach – First, based on the hubris hypothesis, this study reviews the literature on CEO overconfidence and overseas M&A. Second, this study uses the case analysis method, taking Techcent Environmental Co., Ltd., as an example, to study the impact of CEO overconfidence on the motivation, payment method, and corporate performance of overseas M&A. Findings – Overconfident CEOs tend to make enterprises carry out overseas M&As and use cash in the settlement. At the same time, overconfident CEO overseas mergers and acquisitions have a negative impact on both short-term and long-term corporate performance. Research Implications – This study expands the scope of case studies on the theory of executive overconfidence in behavioral finance, verifies the hubris hypothesis, enriches the case study literature on CEO confidence in behavioral finance, and provides reference for the management and overseas M&As of corporate executives.
Investment Value of an Enterprise in New Energy Vehicles: A Case Study of BYD Company
Authors:   Asian Trade Association, Tian Fang
Published: August 2023

Purpose – In recent years, new energy vehicles have undergone qualitative changes and witnessed a doubling of trading volume. Most of the existing research on new energy vehicles derive valuation methods from traditional automobile companies. This paper aims to establish an effective investment value analysis model and determine a reasonable investment range through comprehensive analysis of the internal and external environment of the company, so as to provide investors with more specific references for investment value. Design/Methodology/Approach – Based on value investment theory, this study compares several major domestic listed new energy vehicle companies and combines financial analysis and valuation methods. Taking BYD, a leading domestic automobile company, as an example, it analyzes the current investment value in the field of new energy vehicles to assist investors in making better investment judgments. Findings – This study comprehensively compares the financial status of BYD and several major new energy vehicle companies in terms of profitability, solvency, and development capability. Using the PE valuation method, the study concludes that in the short term, the valuation of listed companies in the new energy vehicle sector is generally too high, indicating a certain bubble, and investors should exercise caution. In the medium to long term, investors can sustain their focus. Research Implications – This study provides a comprehensive, objective, and rigorous research method for stock valuation by comparing financial data, PE, and PB. Investors should analyze the impact of changes in financial data, policy changes, and technological advancements on the valuation of investment enterprises. In the future, they can intervene within a reasonable valuation range to obtain greater returns with lower risks.
Paternalistic leadership and organizational commitment: Evidence from the information technology sector
Authors: Ghayas Muhammad Muzammil , Khan Malik Muhammad Sheheryar , Singh Etinder Pal , Alajlani Sami Emadeddin , Ghafar Abdul
Published: August 2023

This research aims to test the relationship between dimensions of paternalistic leadership and dimensions of organizational commitment in the information technology (IT) sector of Istanbul. Two separate questionnaires were adapted for measuring dimensions of paternalistic leadership (Erben & Güneşer, 2008) and organizational commitment (Allen & Meyer, 1990). Data were collected at two different points in time from such employees of the IT sector of Istanbul who have been working with the same manager for at least six months. In all, 350 pairs of questionnaires were distributed and only 248 pairs of questionnaires were received. Three separate multiple regression analyses were used as the statistical technique. Results indicated that two of the dimensions of paternalistic leadership, namely benevolent leadership and moral leadership, have a significant relationship with the three dimensions of organizational commitment, namely affective, normative, and continuance commitment. However, authoritarian leadership is found to be negatively associated with affective commitment, whereas, it does not have any significant association with normative and continuance commitment. Therefore, it is concluded that benevolent leadership and moral leadership can be instrumental in enhancing the level of organizational commitment among the employees, whereas, authoritarianism can be counterproductive in nature. Hence, the study provides the framework to the managers in the IT sector of Istanbul for enhancing the organizational commitment among the employees.
Women’s political representation in local government: Its impact on public service quality
Authors: Aryani Y. Anni , Gantyowati Evi , Nurrahmawati An , Arifin Taufiq , Sutaryo Sutaryo
Published: August 2023

Public service quality has been a significant issue in Indonesia (Lanin & Hermanto, 2019) along with woman’s representation in politics (Aspinall et al., 2021). This study investigates the effect of woman’s representation in the local government head and legislative positions on public service quality in Indonesian local governments. We use secondary data from the Ministry of Internal Affairs, a local government website, and the Indonesia Statistics Bureau from 2016–2019, analyzed with panel data regression analysis. Overall, we find that local government public service quality is at a high level. Meanwhile, women’s political representation in Indonesian local government is still considerably low, both in legislative and top executive positions. Empirical findings demonstrate that women’s representation in the legislative board provides a positive impact on public service quality while women’s local government head has no significant effect. The effect is consistent both in district local governments and city local governments observations. Our study provides recommendations that suggest that women’s representation in local politics should be increased to promote gender equality which leads to better public governance
Elementos de Física Moderna Avanzada
Authors: Ruden Muñoz Alexander , Trujillo Lemus Juan Pablo , Cardona Hernández Jorge Andrés
Published: August 2023

El trabajo titulado ELEMENTOS DE FISICA MODERNA AVANZADA es una obra realizada con el fin de exponer algunos elementos claves de la física del siglo XX en el ámbito académico y muy en especial para aquellas personas que usan la física como el principal instrumento en investigaciones o aplicaciones ingenieriles. El texto presentado, es consecuencia de un esmerado análisis por parte de los autores, sobre las experiencias de la enseñanza y el aprendizaje de la física moderna en el siglo XXI y las necesidades de los estudiantes/profesores de la Universidad Tecnológica de Pereira en el que hacer académico y desarrollador. Por otra parte, el manuscrito tiene como propósito, entregar una herramienta a los estudiantes que iniciarán sus cursos de física avanzada en carreras de pregrado y posgrado, como: Licenciatura en Matemáticas y Física, Ingeniería Física, Maestría en Instrumentación Física, Doctorado en Ciencias, los cuales requerirán disponer material bibliográfico de formación básica. Los temas mostrados en la obra, son tratados de manera que el lector pueda seguir una línea coherente en los contenidos, los cuales se tratan de manera intuitiva respetando el rigor.
A Critical Study of Composition Algorithms in Differential Privacy
Authors: Yogi Manas Kumar , DrASNChakravarthy *
Published: August 2023

Differential privacy has emerged as a prominent framework for
safeguarding individual privacy in the context of data analysis and
statistical computations. With the proliferation of data-driven
applications and the necessity to share sensitive information while
preserving confidentiality, the study of composition algorithms in
differential privacy becomes increasingly vital. This paper presents a
critical examination of the various composition techniques employed to
combine multiple privacy-preserving computations while upholding the
integrity of the overarching privacy guarantees. The paper begins by
outlining the fundamental principles of differential privacy and its
significance in contemporary data-centric environments. It subsequently
delves into a critical analysis of sequential composition, parallel
composition, and advanced composition theorems. The inherent strengths
and limitations of each technique are scrutinized; emphasizing their
practical implications in preserving privacy across different scenarios.
The study extends beyond basic composition strategies to explore
intricate facets of composition algorithms. Post-processing and
renewal-based composition methodologies are evaluated in the context of
preserving privacy amidst evolving data landscapes. The paper also
investigates adaptive data analysis and hierarchical composition,
elucidating their roles in addressing complex privacy challenges that
arise in multi-agent and multi-level environments. Through a meticulous
survey of literature and practical implementations, this paper unveils
the nuanced interplay between composition algorithms and differential
privacy mechanisms. It highlights the need for judicious application of
composition techniques while considering the dynamic interactions
between privacy parameters, data characteristics, and adversarial
behaviours. Furthermore, the paper underscores the significance of
incorporating advanced composition theorems to yield more precise
privacy bounds, providing a comprehensive understanding of the
intricacies involved.
Therapeutic Potential of Sol-Gel ZnO Nanocrystals: Anti-Cancer, Antioxidant, and Antimicrobial Tri-Action
Authors: Eren Busra , Gunduz Meliha Koldemir , Kaymak Gullu , Berikten Derya , Bahsi Zehra
Published: August 2023

Zinc oxide nanocrystals (ZnO NCs) hold great promise in nanomedicine,
with fascinating multifunctional properties. We investigated the
therapeutic potential of sol-gel synthesized ZnO NCs with crystal sizes
of 52.65 nm and 25.11 nm, focusing on their anti-cancer effects on HepG2
and HT29 cells, antioxidant properties, and antimicrobial activity. Both
samples displayed a hexagonal wurtzite ZnO structure, wherein the
crystal sizes diminished with lower calcination temperatures according
to the XRD. The scanning electron microscopy (SEM) analysis revealed
that lowering the calcination temperature resulted in a decrease in the
grain size of the ZnO nanocrystals, as expected. This reduction in grain
size combined with a decrease in crystal size resulted in a significant
40% reduction in the reflectance of the ZnO nanocrystals in UV-Vis-NIR
spectroscopy. In both cell lines, the cytotoxic potential was found to
be higher in HepG2 cells. Specifically, when using ZnO nanocrystals
(NCs) with a crystal size of 25.11nm, the lowest cell viability was
observed at a concentration of 250 μg/ml. Based on oxidative stress
index (OSI) values, lower crystal size of ZnO NCs displayed greater
effectiveness in HT29 cells, while higher crystal size of ZnO NCs had
pronounced effects in HepG2 cells. Moreover, both ZnO NCs, especially
25.11nm size of ZnO NCs at low concentrations, exhibited significant
antimicrobial activity against Gram-positive bacteria (E. faecalis, S.
aureus) and C. parapsilopsis fungus. These findings emphasize sol-gel
ZnO nanocrystals’ potential as versatile agents in nanomedicine,
spurring research on targeted cancer therapies and antimicrobial
innovations.
Design and development of robotic system for precise vascular access and autonomous veinpuncture
Authors: Kim Seho , Choi Seonil , Yeom kiwon
Published: August 2023

The medical robot systems have the effect of reducing the work load and
preventing accidents by supporting task that are difficult for
inexperienced medical practitioners. Recently, research on automated
blood collection and injection robotic system has been increasing, but
work is still necessary such as replacing needle tips, setting
tourniquet and fixing the patient’s arm. In this letter, we propose an
intelligent intravenous injection robot without having to see the
medical workers face-to-face. We design a revolving system for automatic
needle replacement and an arm holder for vessel fixation. Finally, we
experiment positioning the needle at the target point by position
control based on mathematical modeling and velocity kinematics.
Hybrid Quicksort for Referenced Items with 1 and 3 pivots
Authors: Champeaux Dennis de
Published: August 2023

This paper has multiple deliverables: the need for two different
quicksort algorithms, the need for a hybrid with more than 2 design
layers and at least 3 members, a new technique for obtaining pivots, a
novel one pivot version extended with the Edelkamp enhancement and
several three pivot versions. Each topic has its own section with a
description of the underlying ideas and the benefits shown by
performance results. Topic N+1 builds on top of topic N. All versions
have O(NlogN) worst case complexity and linear complexity on constant
inputs. Novel design elements are, among others: using the single
element moving technique (in addition to pairwise swapping) and using
array layouts with two gaps (in addition to single gap layouts). Given
our focus on arrays with referenced items we assess our versions (in
addition to timings) with comparison counts instead of with swap counts.
We compare our versions favorably against quicksort versions we found in
libraries and elsewhere.
HB-EGF-loaded nanovesicles enhance trophectodermal spheroid attachment and invasion
Authors: Poh Qi Hui , rai alin , Cross Jonathon , Greening David
Published: August 2023

The ability of trophectodermal cells (outer layer of the embryo) to
attach to the endometrial cells and subsequently invade the underlying
matrix are critical stages of embryo implantation during successful
pregnancy establishment. Extracellular vesicles (EVs) have been
implicated in embryo-maternal crosstalk, capable of reprogramming
endometrial cells towards a pro-implantation signature and phenotype.
However, challenges associated with EV yield and direct loading of
biomolecules limit their therapeutic potential. We have previously
established generation of cell-derived nanovesicles (NVs) from human
trophectodermal cells (hTSCs) and their capacity to reprogram
endometrial cells to enhance adhesion and blastocyst outgrowth. Here, we
employed a rapid NV loading strategy to encapsulate potent implantation
molecules such as HB-EGF (NVHBEGF). We show these loaded NVs elicit
EGFR-mediated effects in recipient endometrial cells, activating kinase
phosphorylation sites that modulate their activity (AKT S124/129, MAPK1
T185/Y187), and downstream signalling pathways and processes (AKT signal
transduction, GTPase activity). Importantly, they enhanced target cell
attachment and invasion. The phosphoproteomics and proteomics approach
highlight NVHBEGF-mediated short-term signalling patterns and long-term
reprogramming capabilities on endometrial cells which functionally
enhance trophectodermal-endometrial interactions. This proof-of-concept
study demonstrate feasibility in enhancing the potency of NVs in the
context of embryo attachment and establishment.
Peptide ligands targeting the vesicular stomatitis virus G (VSV-G) protein for the affinity purification of lentivirus particles
Authors: Menegatti Stefano , Barbieri Eduardo , Mollica Gina N. , Moore Brandyn , Sripada Sobhana Alekhya , Shastry Shriarjun , Kilgore Ryan , Loudermilk Casee M. , Whitacre Zachary H. , Kilgour Katie M. , Wuestenhagen Elena , Aldinger Annika , Graalfs Heiner , Rammo Oliver , Schulte Michael , Johnson Thomas , Daniele Michael A.
Published: August 2023

The recent uptick in the approval of ex vivo cell therapies
highlight the relevance of Lentivirus (LV) as an enabling viral vector
of modern medicine. As labile biologics, however, LVs pose critical
challenges to industrial biomanufacturing. In particular, LV
purification – currently reliant on filtration and anion-exchange or
size-exclusion chromatography – suffers from long process times and low
yield of transducing particles, which translate in high waiting time and
cost to patients. Seeking to improve LV downstream processing, this
study introduces peptides targeting the enveloped protein Vesicular
stomatitis virus G (VSV-G) to serve as affinity ligands for the
chromatographic purification of LV particles. An ensemble of candidate
ligands was initially discovered by implementing a dual-fluorescence
screening technology and a targeted in silico approach designed
to identify sequences with high selectivity and tunable affinity. The
selected peptides were conjugated on Poros resin and their LV
binding-and-release performance was optimized by adjusting the flow
rate, composition, and pH of the chromatographic buffers. Ligands
GKEAAFAA and SRAFVGDADRD were selected for their high product yield
(50-60% of viral genomes; 40-50% of HT1080 cell-transducing particles)
upon elution in PIPES buffer with 0.65 M NaCl at pH 7.4. The
peptide-based adsorbents also presented remarkable values of binding
capacity (up to 3·10 TU per mL of resin at the
residence time of 1 min) and clearance of host cell proteins (up to
220-fold reduction of HEK293 HCPs). Additionally, GKEAAFAA demonstrated
high resistance to caustic cleaning-in-place (0.5 M NaOH, 30 min) with
no observable loss in product yield and quality.
Experimental results and analysis of a 2-transmitter wireless power transfer system in seawater at midrange
Authors: Gan Luoxiu , Niu Wangqiang
Published: August 2023

Wireless power transfer (WPT) system in seawater exhibits distinct
transmission characteristics from those in air due to the unique
properties of seawater medium and the complexity of the seawater
environment. In this paper, a 2-transmitter (2TX) and 1-receiver (1RX)
WPT system in the frequency band of 350~550 kHz in
seawater is observed. When the transfer distance is at midrange, the
maximum load voltage point of the system is shifted from 460 kHz to 430
kHz compared to that in air, and the maximum transfer efficiency is 7
times of that in air. The system maintains a stable output voltage when
the receiving coil is at different offsets. To grasp the influence
mechanism of seawater on wireless power transfer, two new parameters,
complex self-inductance and complex mutual inductance, are introduced
into the circuit model to summarize the propagation of electromagnetic
waves in attenuating medium, and the model is verified through
experiments.
Tradeoffs between temporal and spatial pattern calibration and their impacts on robustness and transferability of hydrologic model parameters to ungauged basins
Authors: Demirel Mehmet Cüneyd , Koch Julian , Rakovec Oldrich , Kumar Rohini , Mai Juliane , Müller Sebastian , Thober Stephan , Samaniego Luis , Stisen Simon
Published: August 2023

Optimization of spatially consistent parameter fields is believed to
increase the robustness of parameter estimation and its transferability
to ungauged basins. The current paper extends previous multi-objective
and transferability studies by exploring the value of both multi-basin
and spatial pattern calibration of distributed hydrologic models as
compared to single-basin and single-objective model calibrations, with
respect to tradeoffs, performance and transferability. The mesoscale
Hydrological Model (mHM) is used across six large central European
basins. Model simulations are evaluated against daily streamflow
observations at the basin outlets and remotely sensed evapotranspiration
patterns obtained with a two-source energy balance approach. Several
model validation experiments are performed through combinations of
single- (discharge) and multi-objective (discharge and spatial
evapotranspiration patterns) calibrations with holdout experiments
saving alternating basins for model evaluation. The study shows that
there are very minimal tradeoffs between spatial and temporal
performance objectives and that a joint calibration of multiple basins
using multiple objective functions provides the most robust estimations
of parameter fields that perform better when transferred to ungauged
basins. The study indicates that particularly the multi-basin
calibration approach is key for robust parametrizations, and that the
addition of an objective function tailored for matching spatial patterns
of ET fields alters the spatial parameter fields while significantly
improving the spatial pattern performance without any tradeoffs with
discharge performance. In light of model equifinality, the minimal
tradeoff between spatial and temporal performance shows that adding
spatial pattern evaluation to the traditional temporal evaluation of
hydrological models can assist in identifying optimal parameter sets.
A mineralogic approach to estimating the volume of dissolution, alteration, and unaltered residue from weathering of different provenance lithotypes
Authors: Heins William Andrew , Brengman Latisha A
Published: August 2023

Evaluation of the approximate magnitude of the gross discrepancy between
the volume of sediment produced on the hinterland and the volume
deposited in the basin, over long time and length scales, is required to
make source-to-sink sediment mass-balance calculations more accurate so
that multiple sources for a single widespread stratigraphic unit, or
bypass of the unit, might be more easily detected.

This paper outlines a method to characterize the sources of sediments,
or provenance lithotypes, according to their relative ability to produce
dissolved ions, clay minerals, and unaltered residue at different levels
of weathering. Estimating the relative proportion of the hinterland that
is dissolved supports mass-balance analysis comparing hinterland
denudation with basinal deposition, whereas estimating the relative
proportion of clay (both original clay, eroded from mudstone, for
example, as well as newly created clay produced by weathering of
feldspar) supports potential identification of multiple sediment
sources. The method is illustrated with a practical example from the
Bohemian Massif and documented with an Excel workbook.

This is a mineralogical approach based on mineral inventories of
weathering profiles. Even if the prediction is necessarily uncertain
because the mineralogical representation of the PLs are gross
abstractions, the modelled transformation processes are crude cartoons,
and the extent of transformation under different environmental
conditions is wild speculation based on sparse examples, quantitative
provenance analysis will be more accurate and more precise than it would
be if dissolution and alteration were not explicitly accounted. There is
ample opportunity for the community to improve the procedure!
Characterizing Non-phase-locked Tidal Currents in the California Current System using High-frequency Radar
Authors: Kachelein Luke , Gille Sarah T. , Mazloff Matthew R. , Cornuelle Bruce
Published: August 2023

Over nine years of hourly surface current data from high-frequency radar
(HFR) off the US West Coast are analyzed using a Bayesian least-squares
fit for tidal components. The spatial resolution and geographic extent
of HFR data allow us to assess the spatial structure of the
non-phase-locked component of the tide. In the frequency domain, the
record length and sampling rate allow resolution of discrete tidal lines
corresponding to well-known constituents and the near-tidal broadband
elevated continuum resulting from amplitude and phase modulation of the
tides, known as cusps. The FES2014 tide model is used to remove the
barotropic component of tidal surface currents in order to evaluate its
contribution to the phase-locked variance and spatial structure. The
mean time scale of modulation is 243 days for the M$_2$ constituent
and 181 days for S$_2$, with overlap in their range of values. These
constituents’ modulated amplitudes are significantly correlated in
several regions, suggesting shared forcing mechanisms. Within the
frequency band M$_2$ $\pm$ 5 cycles per year, an
average of 48\% of energy is not at the phase-locked
frequency. When we remove the barotropic model, this increases to
64\%. In both cases there is substantial regional
variability. This indicates that a large fraction of tidal energy is not
easily predicted (e.g. for satellite altimeter applications). The
spatial autocorrelation of the non-phase-locked variance fraction drops
to zero by 150 km, comparable to the width of the swath of the recently
launched Surface Water and Ocean Topography (SWOT) altimeter.
Spectral Analysis of the Magnetic Susceptibility Record of Chinbse Lobss
Authors: Kane R. P. , Trivedi N. B.
Published: August 2023

The magnetic susceptibility record of the Chinese Loess Plateau for the last 2.5 million years was subjected to Maximum Entropy Spectral Analysis. The portion 0 800 ka B.P. showed 95,000 years as the strongest peak, resembling the 98,000 year peak in the spectra of oxygen isotope series from deep-sea cores, and matching the eccen- tricity peak of Earth's rotation axis. The astronomical peaks 19,000 and 23,000 years related to Earth's precession and 41,000 years relater Earth's obliquity was also observed but weakly. For earlier periods (800 ka - 2400 ka B.P.), nine peaks were observed (including 41,000 and 100,000 years) but weakly.ANÁLISE ESPECTRAL DOS REGISTROS DE SUSCEPTIBILIDADE MAGNÉTICA DOS "LOESS" CHINESES Os registros de susceptibilidade magnética do Platô Chinês "Loess" nos últimos 2,5 milhões de anos foram sujeitos à Análise Espectral de Máxima Entropia. A porção 0-800 mil anos anteriores ao presente mostrou 95.000 anos como o mais intenso pico, aparecendo com um pico de 98.000 anos no espectro da série de isótopos de oxigênio apresentada nos sedimentos marinhos profundos, e coincidem com o pico na excentricidade do eixo de rotação da Terra. Os picos astronômicos em 19.000 e 23.000 anos relacionados à precessão da Terra e em 41.000 anos relacionados à obliquidade da terra foram observados, porém muito fracamente. Para períodos anteriores (800-2.400 mil anos anteriores ao presente), nove picos foram observados (incluindo 41.000 e 100.000 anos), porém fracamente.