bluuebunny/crossref_metadata_2025 huggingface dataset:
Discordance in LVEF Between Nuclear SPECT and Echocardiography in Patients With Moderate Reduction in LVEF
Authors: Rawala Muhammad Shabbir , Memon Adil , Yasin Muhammad , Karpe Vallabh , Brewer Zachary S. , Harrington Cecilia V. , Kemper Suzanne E. , Carter William H.
Published: February 2019

Left ventricular ejection fraction (LVEF) is vital to manage heart failure (HF). Studies have reported variable correlations for LVEF between echocardiography (ECHO) and single-photon emission computed tomography (SPECT). A retrospective review of 235 patients was conducted to compare LVEF via ECHO and SPECT done within 72 hours. Mean LVEF by ECHO was 51% and 57% by SPECT. A moderately positive correlation resulted ( r = .76, P ≤ .05) for all, but a weak correlation was noted in 99 with LVEF of 25% to 50% ( r = .43, p≤0.05). Further imaging may be needed for discordant results when medications and/or devices are considered.
Students' Family Support, Peer Relationships, and Learning Motivation and Teachers Fairness Have an Influence on the Victims of Bullying in Middle School of Hong Kong
Authors: Zhao Ruo Bing , Chang Yuan-Cheng
Published: February 2019

This study aims to explore the effect of students’ family socio-economic status, gender, family support, learning motivation and peer relationships and teachers’ equity on the victims of school bullying in Hong Kong. Additionally, the model was analyzed by SEM. The participants in this study were 15 year-old middle school students living in Hong Kong. The data were collected from the PISA 2015 database and the valid number was 4856. The results indicating that family support, peer relationships, and teacher fairness have a negative influence on school bullying. Family support affects one’s risk of being bullied by influencing learning motivation. Peer relationship affects one’s risk of being bullied by influencing learning motivation. Teacher fairness affects one’s risk of being bullied by influencing learning motivation.  
Experimental wavelength-space division multiplexing of quantum key distribution with classical optical communication over multicore fiber
Authors: Cai Chun , Sun Yongmei , Zhang Yongrui , Zhang Peng , Niu Jianing , Ji Yuefeng
Published: February 2019

We demonstrate quantum key distribution (QKD) with classical signals in a seven-core fiber using dense wavelength division multiplexing. Quantum signals are transmitted in an outer core separately and intercore crosstalk (IC-XT) is the main impairment of them. In order to alleviate IC-XT, we propose a quantum-classical interleave scheme. Then the properties of IC-XT are analyzed based on the measurement results, which indicate counter-propagation is a better co-existence method than co-propagation. Finally, we perform QKD experiments in the presence of two classical channels with a channel spacing of 100 GHz between quantum channel and the nearest classical channels. The experiment results prove counter-propagation almost immune to IC-XT, which is consistent with our analysis. Also, the feasibility of the transmission over the range of metropolitan area networks is validated with our scheme.
Morphology and morphometry of adult nematodes on Sumatran elephants (Elephas maximus sumatranus) in Way Kambas National Park area, Indonesia
Authors: Prahardani Rahmania , Firdausy Lintang Winantya , Yanuartono  , Nurcahyo Wisnu
Published: February 2019

Background and Aim: Worms from nematodes are the most numerous and the most detrimental in elephants. Most adult worms are located in the digestive tract. Nematode infection is at higher risk in young elephants, which caused several cases such as anemia, hypoalbuminemia, enteritis, and even death. This study aimed to determine the morphology and morphometry of adult nematodes on Sumatran elephants in Way Kambas National Park area.

Materials and Methods: Nematode samples were obtained from Sumatran elephants' feces (Elephas maximus sumatranus) in Way Kambas National Park, Lampung Province, after being given Kalbazen® containing albendazole 1000 mg at a dose of 10 mg/kg by the veterinarian in charge of the National Park area. For the morphological and morphometric examinations, we used an Olympus BX 51 microscope equipped with Olympus DP 12 camera and were conducted at the Parasitology Laboratory, Faculty of Veterinary Medicine, Universitas Gadjah Mada. The scanning electron microscopic (SEM) analysis was carried out at the Biology Research Center of the Indonesian Institute of Sciences (Lembaga Ilmu Pengetahuan Indonesia).

Results: The results of macroscopic observations of the obtained nematodes showed that the nematodes which were found have the characteristics of round, slim, and white color. The size of a female worm was larger than a male worm. Microscopic examination in four anterior papillae indicated that the dorsal lobe in the copulatory bursa was longer than lateral lobe. The result of inspection with the SEM showed a leaf crown consisting of 10 elements, a pair of amphids laterally, and two pairs of papilla in a submedian region.

Conclusion: Based on our morphology and morphometry examinations of adult nematodes in Sumatran elephant (E. maximus sumatranus) in Way Kambas National Park area, the adult nematodes which were found are species of Quilonia travancra.
Ocorrência das águas subterrâneas no município de Montes Claros - MG: um estudo de caso utilizando a geotecnologia
Authors: Alves Marcela Almeida , Cordeiro Marcos Rodrigues , Milo Renan Laughton
Published: February 2019

O estudo das águas subterrâneas, com a globalização, assume uma importância cada vez mais expressiva, visto que é entendido como um instrumento capaz de prover solução para os problemas de suprimento hídrico. Através de determinadas ferramentas é possível sintetizar o espaço geográfico e aprimorar o estudo deste recurso. Sendo assim, este trabalho teve como objetivo verificar a ocorrência das águas subterrâneas no município de Montes Claros-MG, a fim de ampliar o conhecimento hidrogeológico da região. A metodologia baseou-se em uma pesquisa quali-quantitativa com caráter descritivo, através de um estudo de caso realizado no município com a utilização de ferramentas do Geoprocessamento. Os resultados apresentaram satisfatoriedade na utilização da Geotecnologia, visto que foram obtidos dados relevantes da região em estudo, como o mapeamento da superfície freática, das vazões dos poços perfurados e da topografia local. Pode-se concluir que este estudo permitiu a contribuição e o suporte técnico às políticas públicas para a gestão dos recursos hídricos do município.
URGENSI DAN INTEGRITAS ARSIP DALAM KONTEKS KEBANGSAAN DAN KESADARAN SEJARAH
Authors: Mahmudah Afdini Rihlatul , Rahmi Lailatur
Published: February 2019

Arsip merupakan rekaman peristiwa masa lalu yang di terima oleh lembaga pemerintah, swasta maupun individu. Tulisan ini berfokus pada urgensi dan integritas arsip dalam konteks kebangsaan dan kesadaran sejarah. Tulisan ini bertujuan untuk mengetahui peran arsip dari sejarah yang memiliki fungsi sangat kuat dalam konteks kebangsaan dan menyadarkan masyarakat terhadap sejarah nantinya. Pengumpulan data dengan metode studi kepustakaan. Tulisan ini membahas integritas arsip dalam membangun ulang ingatan manusia terhadap rentetan informasi yang berhubungan dengan sejarah bangsa dan mengulas informasi yang memperkuat semangat pemerintah dalam membangun negara. Keberadaan arsip sejarah yang penting untuk diperhatikan tidak bisa terjaga dengan baik jika tidak dikelola oleh pengelola yang profesional. Pentingnya keberadaan profesional arsip dikenal dengan sebutan Arsiparis mulai dirasakan bagi lembaga pemerintah. Arsiparis diharapkan dapat memudahkan pemerintah dan sejarawan dalam merekonstruksi rangkaian sejarah sebagai catatan penting bagi bangsa. Maka dari itu arsiparis sangat berperan dalam membantu negara agar sadar sejarah dan membantu dalam membangun bangsa.
PEMETAAN PENULISAN SKRIPSI MAHASISWA PROGRAM STUDI S-1 ILMU PERPUSTAKAAN UNIVERSITAS DIPONEGORO
Authors: Krismayani Ika
Published: February 2019

Penelitian ini bertujuan untuk mengetahui pemetaan penulisan skripsi mahasiswa program studi Ilmu Perpustakaan Fakultas Ilmu Budaya Universitas Diponegoro.Metode yang digunakan dalam penelitian ini adalah metode penelitian deskriptif kuantitatif.Populasi dalam penelitian ini adalah skripsi mahasiswa program studi ilmu perpustakaan Fakultas Ilmu Budaya Universitas Diponegoro (baik reguler 1 maupun reguler 2) yang berjumlah 521 judul skripsi. Keseluruhan populasi tersebut diambil sebagai sampel penelitian. Hasil penelitian ini menunjukkan bahwa keragaman subjek dari skripsi yang telah dihasilkan mahasiswa ilmu perpustakaan Universitas Diponegoro sebanyak 22 topik. Dari 22 topik, diketahui bahwa topik yang paling banyak dipilih oleh mahasiswa ilmu perpustakaan universitas diponegoro adalah topik mengenai penggunaan perpustakaan dan penggunanya yaitu sebesar 23,42% (122 judul skripsi).
Pengembangan Aplikasi Elektronik Arsip (E Arsip) Pembelajaran Jurusan Administrasi Perkantoran
Authors: Kuswantoro Agung , Ashari Trisna Novi
Published: February 2019

Fokus penelitian ini adalah pengembangan aplikasi e arsip pembelajaran jurusan administrasi perkantoran.Pertanyaan subfokusnya adalah (1) Apa kendala dalam e arsip pembelajaran program Access? (2) Aplikasi apa yang tepat dalam pengembangan e arsip pembelajaran? (3) Apa kelebihan dari pengembangan aplikasi e arsip pembelajaran ? Tujuan penelitian ini adalah untuk mengetahui pengembangan aplikasi e arsip pembejaran jurusan administrasi perkantoran, yang meliputi (1) kendala dalam e arsip pembelajaran berbasis Access; (2) aplikasi yang tepat dalam pengembangan e arsip pembelajaran;dan (3) kelebihan dari pengembangan aplikasi e arsip pembelajaran. Desain penelitian ini adalah penelitian pengembangan. E arsip programAccess yang selama ini digunakan sering mengalami kendala teknis seperti harus sering me-refress, terjadi kesalahan dalam pengoperasiannya, rentang terkena virus, dan ketergantungan dengan aplikasi Access tahun 2010. Simpulan dalam penelitian ini adalah (1) Kendala dalam E Arsip Pembelajaran dengan program Access dalam bentuk file tidak bisa diedit; (2) Sofware sebagai solusi atas apliasi e arsip pembelajaran dengan program Access; (3) Kelebihan aplikasi e arsip berbasis sofware adalah kesalahan sistem dapat diminimalisir dengan pemprograman. Saran dalam penelitian ini adalah (1) perlu adanya buku petunjuk dalam menginstal dan mengoperasikan aplikasi arsip pembelajaran berbasis sofware (2) perlu adanya latihan yang berkelanjutan untuk mempraktekkan aplikasi arsip pembelajaran berbasis sofware
Persepsi Pemakai terhadap Layanan Repositori UPT Perpustakaan Undip
Authors: Suwanto Sri Ati
Published: February 2019

Tujuan dari penelitian ini adalah menganalisis bagaimana persepsi pemakai terhadap layanan repositori UPT Perpustakaan Undip. Desain penelitian yang digunakan adalah kualitatif dengan jenis penelitian studi kasus. Pengumpulan data menggunakan wawancara, yang kemudian dianalisis secara deskriptif. Subyek penelitian ini adalah UPT Perpustakaan Undip dan objeknya Layanan Repositori Undip.Informan dipilih dengan menggunakan purposive sampling, sebanyak 12 orang dari 12 fakultas. Dari hasil penelitian dapat diketahui bahwa persepsi pemakai terhadap kompetensi pengelola layanan repositori baik dengan penggunaan bahasa  yang mudah, dan cukup sederhana. Akses repositori dinyatakan cukup mudah dan cepat. Persepsi pemakai terhadap tampilan web repositori Undip dianggap masih monoton, kurang bervariasi dalam hal warna tampilan.  Ketersediaan koleksi dinyatakan  terbatas dan pembaharuan koleksi lambat. Hal ini yang  menjadi penyebab utama pemakai merasa bahwa repositori Undip belum melakukan layanannya dengan optimal serta promosi yang kurang maksimal. Persepsi pemakai terhadap kompetensi SDM dinyatakan sudah kompeten, tetapi masih dianggap belum cukup. Disamping itu SDM di masing-masing fakutas belum konsisten dalam pengembangan repositori.
Preoperative proteinuria and clinical outcomes in type B aortic dissection after thoracic endovascular aortic repair
Authors: Yang Hongwei , Zhou Jianwei , Huang Keli , Yu Tao , Wang Zuhui , Chen Heng , Yu Wenshui , Lin Xiaodong , Zhang Yan , Zhu Guoxian
Published: February 2019

Background

Proteinuria is a marker of poor outcomes in several diseases; however, few studies have been conducted to explore the prognostic value of proteinuria, assessed by urine dipstick test, for clinical outcomes in patients with type B acute aortic dissection (TBAD) undergoing thoracic endovascular aortic repair (TEVAR).

Methods

Consecutive patients with TBAD undergoing TEVAR were enrolled from January 2010 to July 2015. Proteinuria was defined as trace or higher, according to the results of urine dipstick testing. Associations among proteinuria and adverse events were evaluated.

Results

In total, 671 patients with a mean age of 44±15 years were included in the analysis. Proteinuria was detected in 281 patients (41.9%) before TEVAR. Multivariate logistic regression analysis showed that C-reactive protein and impaired renal function were independent predictors for proteinuria. During hospitalization, 21 patients died. In-hospital mortality was higher in patients with proteinuria (1.5% vs. 5.3%, p=0.005). After a median 3.4 years follow up, the post-TEVAR death rate was 10.4% (85 patients were lost to follow-up). The long-term cumulative mortality was significantly higher in patients with proteinuria (17.2% vs. 8.2%, log-rank=11.36, p=0.001). Multivariate Cox survival modeling indicated that proteinuria was significantly associated with long-term death, after adjustment for potential confounding risk factors (HR=1.92, p=0.012).

Conclusions

Pre-TEVAR proteinuria was identified as a prognostic marker in patients with TBAD and has potential for application as a convenient and simple risk assessment method before TEVAR.
Irradiated rubber composite with nano and micro fillers for mining rock application
Authors: Eyssa Hanan M. , Mohamed Wael S. , El-Zayat Mai M.
Published: February 2019

In this work, nanosilica and micro carbon black (CB) as a fillers were used to improve the properties of styrene butadiene rubber/natural rubber blends (SBR/NR) crosslinked by γ radiation. Nanosilica was prepared from silica sand and used as eco-friendly material. These composites were characterized by field emission scanning electron microscopy (FESEM) and the measurements of the physic-mechanical and thermal properties were measured. Field emission scanning electron microscopy showed that the composites reinforced by nanosilica and the measurements of the CB are uniformly dispersed in the blends matrix. The results showed that the physico-mechanical and thermal properties were improved indicating a good interaction between the fillers and rubber matrix. The volume fraction measurements confirmed the formation of crosslinking network structure. Meanwhile, the reinforcement of SBR/NR blend loaded with nanosilica showed improved mechanical than blend loaded with both the nanosilica/carbon black and the CB alone. The highest enhancement was obtained for the three fillers by using a concentration of 35 phr at a dose of 150 kGy of γ-irradiation. Thermogravimetric analysis (TGA) indicated that the thermal stability of SBR/NR blend reinforced by nanosilica is higher than those blends reinforced with combined filler the silica. It was also found that the irradiated SBR/NR nanocomposites were more stable than the un-irradiated ones.
The impact of comorbid pain and depression in the United States: results from a nationally representative survey
Authors: Dhanju Simranpal , Kennedy Sidney H. , Abbey Susan , Katz Joel , Weinrib Aliza , Clarke Hance , Bhat Venkat , Ladha Karim
Published: February 2019

Background and aims

The co-morbidity between pain and depression is a target of interest for treatment. However most of the published literature on the topic has used clinical cohorts as the population of interest. The goal of this study was to use a nationally representative sample to explore how health outcomes varied across pain and depression status in a cohort sampled from the general US population.

Methods

This was a cross-sectional analysis of adults ≥18 years in the 2009–2010 National Health and Nutrition Examination Survey. The cohort was stratified into: no pain/depression, pain alone, depression alone, and pain with depression. The primary outcome was self-reported general health status, and secondary outcomes were healthcare visits, overnight hospital stays and functional limitation. Survey weighted logistic regression was used to adjust for potential confounders.

Results

The cohort consisted of 4,213 individuals, of which 186 (4.4%) reported concurrent pain and depression. 597 (14.2%) and 253 (6.0%) were classified with either pain or depression alone, respectively. The majority of individuals with co-morbid pain and depression reported poor health (65.1%, p<0.001) and were significantly more likely than those with neither condition to rate their health as poor after adjustment (OR: 7.77, 95% CI: 4.24–14.26, p<0.001). Those with pain only or depression only were also more likely to rate their health as poor, albeit to a lesser extent (OR: 2.21, 95% CI: 1.21–2.34, p<0.001; OR: 3.75, 95% CI: 2.54–5.54, p<0.001, respectively). A similar pattern was noted across all secondary outcomes. Most notably, those with co-morbid pain and depression were the most likely to endorse functional limitation (OR: 13.15, 95% CI: 8.00–21.61, p<0.001). Comparatively, a similar trend was noted amongst those with pain only or depression only, though with a reduced effect size (OR: 4.23, 95% CI: 3.12–4.77, p<0.001; OR: 5.13, 95% CI: 3.38–7.82, p<0.001).

Conclusions

Co-morbid pain and depression in the general population resulted in markedly worse outcomes versus isolated pain or depression. Further, the effect appears to be synergistic. Given the substantial burdens of pain and depression, future treatments should aim to address both conditions simultaneously.

Implications

As a result of the co-morbidity between pain and depression, patients presenting with either condition should increase the index of suspicion among clinicians and prompt screening for the reciprocal condition. Early intervention for co-morbid pain and depression has the potential to mitigate future incidence of chronic pain and major depression.
El concepto de "expansión" del derecho penal puesto en cuestionamiento. Su relación conflictiva con el concepto de "inflación" penal
Authors: Carrasco Jiménez Edison
Published: February 2019

El presente artículo tiene por objetivo presentar los problemas de que adolece el concepto de “expansión” del derecho penal, y como problema del concepto, por ende, sus problemas metodológicos generales. Tales problemas se originan, en gran parte, por la existencia de un concepto acuñado y ya usado anteriormente por la doctrina penal como lo es el de la “inflación” penal, y el cual se refiere al mismo campo conceptual que el de la “expansión”, cuestión que acarrea problemas de delimitación de este último concepto y de su especificidad frente al primero. Siendo así, encontramos problemas de colisión conceptual entre ambos conceptos, ausencia de criterios objetivos en el diagnóstico de los fenómenos que cubre el concepto, y de ambigüedad semántica del concepto de “expansión”.
Las pruebas genéticas predictivas y el moderno proceso penal
Authors: Velásquez Velásquez Fernando
Published: February 2019

Los avances tecnológicos, entre ellos las llamadas pruebas genéticas predictivas, se asoman al proceso penal actual. Esta reflexión sobre el asunto examina esos instrumentos de cognición y, dentro de ellos, los test que tienen la misma destinación; además, se estudian los bancos de datos y las muestras genéticas y, con un punto de partida garantista, se clama por un control de estas herramientas de cara al proceso penal actual. Por ello, el autor hace un llamado de atención a la academia y a la administración de justicia para evitar que el uso de esos mecanismos, no propicie un derecho penal de autor que arrincone las garantías y dé paso al leviatán.
Financiación de partidos políticos y transparencia: crónica de una resistencia
Authors: Sanjurjo Rivo Vicente Antonio
Published: February 2019

La regulación legislativa de los partidos políticos y, por tanto, también de sus fuentes de financiación, ofrece la singularidad de que son los propios partidos que ocupan el poder legislativo del Estado los que, en última instancia, legislan sobre sí mismos. Por ello los partidos, conscientes de su necesidad de grandes recursos económicos para afrontar sus ingentes gastos, al regular sus fuentes de financiación privada, dejan abiertas posibles vías de financiación que les permita satisfacerlos, sin perjuicio de que simultáneamente se pueda constatar su indudable esfuerzo por regular restrictivamente esas mismas fuentes de financiación. Y esa doble condición de legislador y objeto de la legislación que aúnan los partidos, tal vez sea una de las posibles causas que a su vez explique el limitado impacto que sobre ellos ha tenido la regulación legislativa en materia de transparencia.
Orchards During War: Braceros in the Northwest
Authors: Fabian John
Published: February 2019

The American government introduced the bracero program during World War Two which allowed for Mexican laborers to enter the country to fulfill the nations labor demands. Their employment was on a temporary basis as they were usually signed to one-year contracts and sent all over the country. The Mexican and American governments were tasked at looking after these workers well being while ensuring that they fulfilled the demands that the United States government needed. In places like the American Southwest, braceros had little labor issues with their employers while in the American Northwest, labor stoppages and strikes were constant. The bracero workers of the Northwest generally received less oversight from the Mexican government and therefore the workers took matters into their own hands to ensure that they were being treated fairly. It was the neglect of the American and Mexican governments that drove braceros in the Northwest to organize.
A new record of Bulbophyllum section Aeschynanthoides from Vietnam
Authors: Truong Voung Ba , Vermeulen Jaap J. , Truong Tam Quang
Published: February 2019

Bulbophyllum hainanense is an addition to the Flora of Vietnam. Previously, Vietnamese material of this species was listed as Bulbophyllum hymenanthum, a similar-looking species. This paper provides a description and illustration of the Vietnamese material of B. hainanense. 

Key words: Bulbophyllum hainanense, Hon Ba nature reserve, new record, Vietnam
New record of Serpocaulon triseriale (Sw.) A.R. Sm. (Polypodiaceae) in Argentina, with morphological comparison of relatives
Authors: Sanín David , Martínez Olga G. , Salino Alexandre
Published: February 2019

Serpocaulon triseriale (Sw.) A.R. Sm. is considered the most widespread species in the genus. It has been recorded from south of Mexico to Bolivia, Paraguay and Brazil. Here, we expand its distribution by reporting a new record from Salta province, Argentina, based on material that was previously misidentified as S. polystichum (Link) A.R. Sm. We compare the S. triseriale and S. polystichum with their relatives (S. attenuatum (Humb. & Bonpl. ex Willd.) A.R. Sm., and S. rex Schwartsb. & A.R. Sm.), providing photographs of the plants in the field, SEM images of the spores and light photos of the rhizome scales to discriminate S. rex from S. triseriale. In addition, distributional records are included.
USE OF DIFFERENT PROBIOTICS FOR PREVENTION OF VIBRIOSIS DISEASE ON TIGER SHRIMP LARVAE REARED IN FIBERGLASS TANKSUSE OF DIFFERENT PROBIOTICS FOR PREVENTION OF VIBRIOSIS DISEASE ON TIGER SHRIMP LARVAE REARED IN FIBERGLASS TANKS
Authors: Nurbaya Nurbaya , Atmomarsono Muharijadi
Published: February 2019

To counter disease problems caused by vibriosis in shrimp hatchery, this recent study used three different probiotics to be tested on tiger shrimp (Penaeus monodon) postlarvae. The study arranged four treatments as follows: A: a combination of three liquid-form probiotics Brevibacillus laterosporus BT951, Bacillus subtilis BM12, and B. licheniformis BM58; B: a combination of three powder-form probiotics Brevibacillus laterosporus BT951, Bacillus subtilis BM12, and B. licheniformis BM58; C: a commercial powder probiotic containing Bacillus subtilis; and D: control (without probiotic), each treatment with three replications. This study was set up in a completely randomized design experiment using twelve fiberglass tanks filled with 750 L sterile sea water and stocked with 30,000 nauplii in the Awarange shrimp hatchery of the Research Institute for Brackishwater Aquaculture and Fisheries Extension Installation in Barru. Variables observed in this study were the survival rate of the shrimp postlarvae at the end of the experiment, total vibrio count (TBV) and total plate count of common bacteria (TPC) in the culture water. The results showed that the survival rate of tiger shrimp applied either in liquid (A: 61.5±4.7%) or powder form (B: 48.6±6.8%), and control (without probiotic) (D: 51.2±4.4%) were not significantly different (P>0.05). However, survival rates in these three treatments differed (P<0.05) with that of the commercial probiotic (C: 21.7±9.9%). TBV/TPC ratio in the tank waters treated with the commercial probiotic (2.26-37.52%) was much higher than that of the liquid form probiotic (0.86-1.98%), powder form probiotic (1.25-8.37%), and control (1.93-2.84%). Ammonia-nitrogen in treatment C (1.462-2.989 mg/L) was relatively higher than that of in treatment A (1.595-2.435 mg/L), treatment B (1.644-2.115 mg/L), and treatment D (1.051-1.858 mg/L).
Construction and demolition waste in geopolymer concrete technology: a review
Authors: Dadsetan Sina , Siad Hocine , Lachemi Mohamed , Sahmaran Mustafa
Published: February 2019

Geopolymers are a relatively new generation of construction materials developed with industrial by-products and supplementary cementitious materials (SCMs) with high silica and alumina contents. In recent years, the demand for SCMs has increased significantly due to action plans on global climate change. In addition, construction and demolition wastes (CDWs) are a major concern in the construction sector and using them through the geopolymerisation process has therefore attracted the attention of researchers worldwide. This paper summarises the literature pertaining to the use of CDWs such as concrete, brick and ceramic as source materials in geopolymer technology, either alone or with SCMs. The literature indicates that CDW materials work well as the main source materials in geopolymer technology. However, due to the various parameters in geopolymerisation, research should move toward defining threshold levels and acceptable criteria rather than simply the best composition outcomes.
Tranfection of sgRNA using SpCas9 containing plasmids to generate cell lines with Cas9 v2
Authors: Kaur Binnypreet , Faktorová Drahomíra , Julius Lukeš and , not provided not provided , not provided not provided
Published: February 2019

This protocol describes transfection of ribonucleoprotein (RNP) complexes that consist of purified Cas9 nuclease duplexed with synthetic guide RNA in cultured cells using the AMAXA Nucleo AMAXA Nucleofector II Electroporation system using Program X-001. RNPs complex have only transient expression inside the cell, this allows for the highest levels of editing efficiency and greatly reduces the chances of possible off target and toxic effects of integration of foreignDNA in host genome
The estimation of the relative gene expression in the hypothalamus and liver of agouti mice using quantitative reverse transcription PCR v1
Authors: V. Derkach Kira , O. Zakharova Irina , I. Zorina Inna , Bakhtyukov Andrey , V. Romanova Irina , V. Bayunova Liubov , O. Shpakov Alexander
Published: February 2019

Female C57Bl/6J mice have a mutation in the Ay locus associated with overexpression of ASIP1, an antagonist of the types 3 and 4 melanocortin receptors. This mutation is characterized by the development of the melanocortin-type obesity. After treatment of the agouti mice with metformin (MF) in the different doses for 10 days, the hypothalamus and liver sections of wild-type mice, untreated agouti-mice and MF-treated agouti-mice were dissected, and the expression of the genes encoding the components of the hypothalamic signaling systems and the liver proteins were estimated by a quantitative reverse transcription PCR (qRT-PCR). The total RNA was isolated using ExtractRNA Reagent. The reverse transcription reaction was carried out using MMLV RT kit. The polymerase chain reaction was performed using the qPCRmix-HS SYBR + LowROX, and the amplified signals were detected with the Applied Biosystems® 7500 Real-Time PCR System (“Life Technologies, Thermo Fisher Scientific Inc.”, Waltham, Massachusetts, USA). The primers for the genes of signal proteins were selected using the Primer-BLAST web application. The genes encoding 18S rRNA and hypoxanthine-guanine phosphoribosyl transferase (Hprt) were used as an endogenous control. Relative expression was calculated using the ddCt method compared with the control group.
ECCLESIASTIC TYPIKON FROM THE SCIENTIFIC LIBRARY OF KYIV UNIVERSITY: ATTRIBUTION OF MANUSCRIPT
Authors: Voloshchenko S.
Published: February 2019

The principles of scientific attribution of liturgical cyrillic manuscripts, which has been worked out by author, are examined. The thorough study of Jerusalem Ecclesiastic Typikon from the rare books and manuscripts department’s collection of Maksymovych Scientific Library of Taras Shevchenko National University of Kyiv is conducted. The stages of manuscript attribution are analyzed, including the date identification and localization of its origins and use.

The type and the title of the codex have been identificated by the analysis of book’s texts. The linguistic variant of Church Slavonic language, used for re-writing the copy, is revealed, which has helped to localize the place of creation. Detailed watermark analysis of paper, which the copy had been made of, has allowed to estimate date range of its production. The problematic ascertainment of the date of creation has been also supported by the analysis of the textual sources, studying of palaeographic peculiarities of cyrillic script book, the inner book’s decorative features. The problem of binding production date, its construction, materials and design, is formulated. The state of preservation of manuscript is analysed, which led the author to understanding the extent of book’s relevance for its readers. The history of manuscript restoration and its stages have been studied. The places of use and migration of the copy are revealed on the basis of provenance examination up till its arrival to Maksymovych Scientific Library’s rare books collection.

Key words: Jerusalem Ecclesiastic Typikon, manuscript, Cyrillic manuscript, attribution, codicology, Maksymovych Scientific Library of Taras Shevchenko National University of Kyiv.
Computer Vision Application for Early Stage Smoke Detection on Ships
Authors: Bistrović Miroslav , Čelić Jasmin , Komorčec Domagoj
Published: February 2019

Nowadays, ship’s engine room is fire protected by automatic fire fighting systems, usually controlled from a place located outside the engine room. In order to activate the water mist extinguishing system automatically, at least two different fire detectors have to be activated. One of these detectors is a flame detector that is not hampered by various air flows caused by ventilation or draft and is rapidly activated and the other is smoke detector which is hampered by these flows causing its activation to be delayed. As a consequence, the automatic water mist extinguishing system is also delayed, allowing for fire expansion and its transfer to surrounding rooms. In addition to reliability of the ship’s fire detection system as one of the crucial safety features for the ship, cargo, crew and passengers, using a systematic approach in this research the emphasis is placed on the application of new methods in smoke detection such as the computer image processing and analysis, in order to achieve this goal. This paper describes the research carried out on board ship using the existing marine CCTV systems in early stages of smoke detection inside ship’s engine room, which could be seen as a significant contribution to accelerated suppression of unwanted consequences.
Interdependence of Transport and Tourism
Authors: Kovačić Mirjana , Milošević Tamara
Published: February 2019

The shuttle service in tourism depends on physical accessibility of a destination, on movement within the destination and the transport itself. In today’s world, transport is not just the act of getting to a wanted destination. Moreover, travelling by a certain vehicle can be a tourist attraction, if the transportation means is designed to arouse the feeling of joy and excitement. The purpose of the study is to define the basic determinants of transport and transport infrastructure, and also to explore the role of transport in the development of tourism. The aim is to point out the interdependence of transport and tourism, considering that the development of transport infrastructure has encouraged the development of mass tourism. The authors analyse the importance of transport infrastructure and the quality of transportation means when it comes to choosing a destination for a tourist trip. In order to evaluate the role of transport in the sustainable development of tourism, experts analyse forms of transport which are a tourist attraction by themselves, and provide an overview of certain forms of transport.
Some Legal Questions Concerning Loans and Legal Disputes in the Roman and Medieval Commercial Navigation
Authors: Đukić Zlatko
Published: February 2019

The paper describes basic financial elements of commercial navigation during the Roman and medieval period. These primarily include the persons who financed the voyage, as well as other partners as determined by law. The legal regulation in question concerns maritime loan, a deposit used as an instrument of security for the return of loan ever since the Ancient times by the Phoenicians, Greeks, Romans, and other maritime nations in the Eastern Mediterranean. The oldest legal regulations related to maritime loan can be found in the Roman law, the Rhodian Law on Jettison of Cargo, and the Rhodian Sea Law (Lex Rhodia). The paper analyses elements related to maritime litigation as well as other relevant issues such as maritime flags. In addition, the paper explores the extent of the influence that these regulations have had on the resolution of certain legal issues connected with maritime navigation.
What are the merits of endogenising land-use change dynamics into model-based climate adaptation planning?
Authors: Jafino Bramka Arga , Haasnoot Marjolijn , Kwakkel Jan H
Published: February 2019

Integrated assessment models often treat land-use change as an external driving force. In reality, land-use is influenced by environmental conditions. This paper explores the merits of endogenising land-use change, i.e. making the land-use change a dynamic internal process, in models used for supporting climate adaptation planning. For this purpose, we extend the Waas model, a hypothetical case study used before for testing new model-based climate adaptation approaches. We use a utility-based land-use change model for endogenising the land-use dynamics, evaluate its implications, and identify the conditions under which it becomes important. We find that endogenising land-use dynamics changes the performance of the policies, allows for assessing policies that affect land-use, and widens the outcomes of interest that can be considered. The relevancy of endogenising land-use dynamics depends on (i) the expected severity of future climate change, (ii) the society’s sensitivity to climate events, and (iii) the types of policy options that decision makers want to evaluate. Ignoring the interaction between the environment and the society (in this case land-use) can result in both under- and overestimation of the impacts of adaptation and might limit the adaptation options that are considered.
Simulation based learning methodology in pharmacology: knowledge and perception among second year medical under-graduate students
Authors: Pereira Nicole , Udaykumar Padmaja , Sherif Lulu
Published: February 2019

Background: Simulation-based learning (SBL) enhances problem-solving, improves skills in health care professionals. Authors assessed its use in teaching and learning pharmacology among medical undergraduates exposed to METIman, human patient simulator.Methods: Medical undergraduate students exposed to SBL for over a year (8 clinical pharmacology related scenarios) were asked to fill a validated questionnaire at the end of the academic year.Results: Of 145 students who underwent SBL, the data of 84 were analysed. The overall satisfaction score with SBL was highly significant in 79 (94%) with a score of 26-35. Participants opined that it increases the depth of experience (91.6%), provides a no risk learning and immediate feedback opportunity (93.4%), a good opportunity to come across rare scenarios (86.2%), enhances decision making, communication, teamwork and skill development (92%); opportunity of repeated learning and enhanced patient safety at hospitals (89.28%), reduces the dependency on patients (72.8%), good opportunity for crisis training (88.0%) were other factors favouring the use of SBL. Preference for an increase in the number of classes allotted to simulation (27.4%) and reducing the duration of class (9.6%) were the major suggestions. It is an excellent method to teach and make it interesting to learn pharmacology (80.0%)Total score varied between 23-35 with a mean±SD of 35±30.64. None had a score of 7-15.Conclusions: SBL is an effective teaching and learning methodology with adequate participant satisfaction. It can be of immense utility as a learning tool with better outcome in learning, retention and recall.
Surgical management of axilla: controversy and care
Authors: Dang Shivam , Saini Sunil Kumar , Pattanayak Manisa
Published: February 2019

Background: Surgical staging of the axilla has traditionally provided the best prognostic information about breast cancer. However, the morbidity of a complete axillary clearance outweighs the therapeutic and prognostic benefits of the procedure. Authors observed the types of axillary lymph node dissection (ALND) performed in authors’ institute and the magnitude of morbidities of a complete ALND.Methods: This observational study was conducted at the Cancer Institute of Himalayan Institute of Medical Sciences for a period of one year. Sequelae of ALND was observed at 1, 3 and 6 months in all female patients undergoing axillary dissection as part of surgery for breast cancer.Results: Out of 150 patients 53 (35.33%) presented with locally advanced disease, and 84 (56%) had palpable axillary nodes. All patients with palpable nodes underwent level II-III dissection. 32 patients underwent sentinel node dissection using blue dye only. Tumour size correlated positively with grade of tumour (r =0.36, P <0.001) and number of positive lymph nodes (r = 0.34; P <0.001). There was significant difference in incidence of lymphedema at 6 months in patients who underwent level III dissection (27.38%) as opposed to those who did not (8.92 %) (p <0.05). The incidence of seroma was also more at 1 month in these patients (57.14%) vs (39.28%), (p <0.05). Post-operative pain/ wound infection/Restriction of motion were not statistically significant.Conclusions: Higher stages of presentation require higher levels of axillary dissection. Unwarranted dissection can be avoided by tailoring the surgery during initial clinical assessment.
PERANAN PENYULUH AGAMA ISLAM DALAM DAKWAH
Authors: Ilham Ilham
Published: February 2019

Islam is a religion of da'wah which obliges his followers to preach according to their capabilities. Islamic instructors are part of the implementation of da'wah (da'i) guiding religious life of the people and bearers of the development mission with a religious approach to society. That is why Islamic Religion Counselors play a very important and strategic role in creating a religious, prosperous and happy society. It plays a role as a leader in religious, social and state affairs for its targets, social change agents, and motivators, facilitators and even community development catalysts.
SHARIA LAW OF TAX AMNESTY IN PERSPECTIVE OF THE SOUTH KALIMANTAN MUSLIM ECONOMISTS
Authors: Mansyuroh Firqah Annajiyah
Published: February 2019

Abstract: The rising standard of living will require an ever-increasing budget. This can be seen from the size of the Indonesian government budget for 2017, revenue in the APBN only Rp 1750.3 trillion while spending reached Rp 2,080.5 trillion. One way to increase state revenues without adding a new burden to the community is through a tax amnesty program. This policy then from the legal aspect, especially the tax amnesty legislation contains legitimacy about not enforcing the applicable laws and regulations, especially regarding administrative sanctions, criminal sanctions and legal form of tax amnesty arrangement itself. From the legal aspects of Islam, this policy of tax amnesty cannot be ignored to see the elements of maslahat and mafsadat or the dominant effect it causes in society. Therefore, author consider the Muslim economist is the right person to be consulted about the policy of tax amnesty, so that the research on tax amnesty perspectives Muslim economist South Kalimantan conducted. This research is empirical law research, which is research done in certain environment, in this case done in South Kalimantan Province. The results found are Muslim economists of South Kalimantan have a view that is divided into two in terms of tax amnesty policy, namely agree and disagree. Those who agree with this policy have the foundation of the priestly (government) policy on the people based on the benefits and considering the amount of benefits obtained compared to the non-tax amnesty.
Predicting mathematics achievement: The role of perceived feedback, teacher support and self-beliefs
Authors: YILDIRIM Selda , YILDIRIM Hüseyin Hüsnü
Published: February 2019

In
this study, the mediating roles of perceived teacher support and students'
mathematics self-beliefs on the feedback process were investigated in The
Programme for International Student Assessment (PISA) context in Turkey. PISA
2012 mathematics scores and questionnaire responses of 4848 15-year-old
students were analyzed. Results indicated that perceived feedback was
positively related to math self-concept and negatively related to math anxiety.
The investigated indirect effects were partly confirmed: perceived feedback was
indirectly related to students' mathematics achievement via perceived teacher
support and math self-efficacy. Also, perceived feedback showed an indirect
effect on students' mathematics achievement via math anxiety. However, the
influences of perceived teacher support on math self-concept and anxiety, and
the mediating role of math self-concept were not supported. The results suggest
the importance of investigation of mediated effects of teachers' support and
students' self-beliefs between teachers' feedback and mathematics achievement.
These relationships may help to understand how teacher's feedback influences mathematics
achievement.
EFFECTS OF LONG-TERM CONTINUOUS POSITIVE AIRWAY PRESSURE THERAPY (CPAP) ON EPICARDIAL FAT THICKNESS AND ARTERIAL STIFFNESS IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA AND HYPERTENSION
Authors: Gorbunova M. V. , Babak S. L. , Malyavin A. G.
Published: February 2019

Background:obstructive sleep apnea (OSA) is associated with high prevalence of arterial hypertension (AH), obesity, violation of carbohydrate metabolism and dyslipidemia. However, the effects of CPAP therapy to improve epicardial fat thickness of the OSA patient with AH the are poorly understood and poorly studied.

Study objective:the aim of the study was to investigate 12-month effects of CPAP therapy with auto-adaptation to inhalation and exhalation of the OSA patient with AH and metabolic disorders (A-Flex therapy) on epicardial fat thickness (EFT).

Methods:to the prospective single-center study were included 310 patients with OSA and AH (273 male, 45,3 ± 10,4 yr.) with apnea-hypopnea index (AHI) >5 events /hour. The night polygraphy study (PG) was performed to calculate AHI, oxygen desaturation index (ODI), mean nocturnal saturation (SpO 2 ) by the rules of American Academy of Sleep Medicine (AASM). The calculation of the epicardial fat thickness (EFT), the size and volume of the heart cavities, left ventricular mass index (LVMI) were performed by two-dimensional echocardiography. Endothelial functionof blood vessels determined by finger test was measured according to peripheral arterial tone (PAT). The reactive hyperemia index (RHI) and augmentation index (AI) was calculated. Optimal level of A-Flex therapy was adjusted at home. AHI, the level of air leakage, average pressure and compliance to CPAP treatment were established in accordance with international requirements.

Results:after 3 months of A-Flex therapy we found a significant decrease of HOMA-IR -1,09 (95% Cl from -1,74 to -0,96; P=0,021), decrease AI -10.8% (95% Cl from -13,70 to -4.6; P=0,001), decrease EFT -1,26 mm (95% Cl from -2,2 to -0,95; P=0,001) in mild OSA patients. After 6 months of A-Flex therapy we found a significant decrease of HOMAIR -2,81 (95% Cl from -3,74 to -1,46; P=0,001), decrease AI -15.6 % (95% Cl from -17,23 to -11,75; P=0,001), decrease EFT -2,15mm (95% Cl from -3,2 to -1,5; P=0,001) in moderate OSA patients. After 12 months of A-Flex therapy we found a significant decrease of HOMA-IR -4,22 (95% Cl from -5,36 to -2,35; P=0,001), decrease AI -21,05 % (95% Cl from -26,5 to -17,4; P=0,001), decrease EFT -4,0 mm (95% Cl from-5,8 to -2,7; P=0,001) in severe OSA patients.

Conclusions:The 12-month A-Flex therapy in moderate and severe OSA patients with AH has a significant therapeutic effect of stabilization systolic and diastolic blood pressure, level of blood lipids and epicardial fat thickness, level of endothelial dysfunction. The 12-month A-Flex therapy has to able to reduce the risks of cardiovascular events in moderate and severe OSA patients with acute metabolic manifestations.