bluuebunny/crossref_metadata_2025 huggingface dataset:
Rhodopsin: Structural Basis of Molecular Physiology
Authors: Menon Santosh T. , Han May , Sakmar Thomas P.
Published: December 2017

The crystal structure of rod cell visual pigment rhodopsin was recently solved at 2.8-Å resolution. A critical evaluation of a decade of structure-function studies is now possible. It is also possible to begin to explain the structural basis for several unique physiological properties of the vertebrate visual system, including extremely low dark noise levels as well as high gain and color detection. The ligand-binding pocket of rhodopsin is remarkably compact, and several apparent chromophore-protein interactions were not predicted from extensive mutagenesis or spectroscopic studies. The transmembrane helices are interrupted or kinked at multiple sites. An extensive network of interhelical interactions stabilizes the ground state of the receptor. The helix movement model of receptor activation, which might apply to all G protein-coupled receptors (GPCRs) of the rhodopsin family, is supported by several structural elements that suggest how light-induced conformational changes in the ligand-binding pocket are transmitted to the cytoplasmic surface. The cytoplasmic domain of the receptor is remarkable for a carboxy-terminal helical domain extending from the seventh transmembrane segment parallel to the bilayer surface. Thus the cytoplasmic surface appears to be approximately the right size to bind to the transducin heterotrimer in a one-to-one complex. Future high-resolution structural studies of rhodopsin and other GPCRs will form a basis to elucidate the detailed molecular mechanism of GPCR-mediated signal transduction.
Capsaicin Protects Cardiomyocytes against Anoxia/Reoxygenation Injury via Preventing Mitochondrial Dysfunction Mediated by SIRT1
Authors: He Huan , Zhou Yue , Huang Jiyi , Wu Zelong , Liao Zhangping , Liu Dan , Yin Dong , He Ming
Published: December 2017

Capsaicin (Cap) has been reported to have beneficial effects on cardiovascular system, but the mechanisms underlying these effects are still poorly understood. Apoptosis has been shown to be involved in mitochondrial dysfunction, and upregulating expression of SIRT1 can inhibit the apoptosis of cardiomyocytes induced by anoxia/reoxygenation (A/R). Therefore, the aim of this study was to test whether the protective effects of Cap against the injury to the cardiomyocytes are mediated by SIRT1. The effects of Cap with or without coadministration of sirtinol, a SIRT1 inhibitor, on changes induced by A/R in the cell viability, activities of lactate dehydrogenase (LDH), creatine phosphokinase (CPK), levels of intracellular reactive oxygen species (ROS), and mitochondrial membrane potential (MMP), related protein expression, mitochondrial permeability transition pore (mPTP) opening, and apoptosis rate in the primary neonatal rat cardiomyocytes were tested. Cap significantly increased the cell viability, upregulated expression of SIRT1 and Bcl‐2, and decreased the LDH and CPK release, generation of ROS, loss of MMP, mPTP openness, activities of caspase‐3, release of the cytochrome c, and apoptosis of the cardiomyocytes. Sirtinol significantly blocked the cardioprotective effects of Cap. The results suggest that the protective effects of Cap against A/R‐induced injury to the cardiomyocytes are involved with SIRT1.
Predicting the Currency Market in Online Gaming via Lexicon-Based Analysis on Its Online Forum
Authors: Kim Young Bin , Kang Kyeongpil , Choo Jaegul , Kang Shin Jin , Kim TaeHyeong , Im JaeHo , Kim Jong-Hyun , Kim Chang Hun
Published: December 2017

Transactions involving virtual currencies are becoming increasingly common, including those in online games. In response, predicting the market price of a virtual currency is an important task for all involved, but it has not yet attracted much attention from researchers. This paper presents user opinions from online forums in a massive multiplayer online game (MMOG) setting widely used around the world. We propose a method for predicting the next-day rise and fall of the currency used in an MMOG environment. Based on analysis of online forum users’ opinions, we predict daily fluctuations in the price of a currency used in an MMOG setting. Focusing specifically on the World of Warcraft game, one of the most widely used MMOGs, we demonstrate the feasibility of predicting the fluctuation in value of virtual currencies used in this game community.
Assessment of Child Immunization Coverage and Associated Factors with Full Vaccination among Children Aged 12–23 Months at Mizan Aman Town, Bench Maji Zone, Southwest Ethiopia
Authors: Meleko Asrat , Geremew Mesfin , Birhanu Frehiwot
Published: December 2017

Immunization remains one of the most important and cost-effective public health interventions to reduce child mortality and morbidity. Globally, it is estimated to avert between 2 and 3 million deaths each year. In Ethiopia, immunization coverage rates stagnated and remained very low for many years. Thus, this study was aimed to assess child immunization coverage and factors associated with full vaccination among children aged 12–23 months in Mizan Aman town. The study design was community-based cross-sectional survey. Data was collected by using pretested structured questionnaire. A total of 322 mothers/caretakers were interviewed. Based on vaccination card and mothers/caretakers’ recall, 295 (91.6%) of the children took at least a single dose of vaccine. From total children, 27 (8.4%) were not immunized at all, 159 (49.4%) were partially immunized, and 136 (42.2%) were fully immunized. Mothers/caretakers educational level, fathers’ educational level, place of delivery, maternal health care utilization, and mothers/caretakers knowledge about vaccine and vaccine-preventable disease showed significant association with full child immunization. The finding from this study revealed that child immunization coverage in the studied area was low. Thus the town health office and concerned stakeholders need to work more to improve performance of the expanded program on immunization in this area.
In Vitro Evaluation of Cocoa Pod Husk Pectin as a Carrier for Chronodelivery of Hydrocortisone Intended for Adrenal Insufficiency
Authors: Adi-Dako Ofosua , Ofori-Kwakye Kwabena , Boakye-Gyasi Mariam El , Oppong Bekoe Samuel , Okyem Samuel
Published: December 2017

This study evaluated the in vitro potential of cocoa pod husk (CPH) pectin as a carrier for chronodelivery of hydrocortisone intended for adrenal insufficiency. FTIR studies found no drug-CPH pectin interactions, and chemometric analysis showed that pure hydrocortisone bears closer similarity to hydrocortisone in hot water soluble pectin (HWSP) than hydrocortisone in citric acid soluble pectin (CASP). CPH pectin-based hydrocortisone matrix tablets (~300 mg) were prepared by direct compression and wet granulation techniques, and the tablet cores were film-coated with a 15% HPMC formulation for timed release, followed by a 12.5% Eudragit® S100 formulation for acid resistance. In vitro drug release studies of the uncoated and coated matrix tablets in simulated gastrointestinal conditions showed that wet granulation tablets exhibit greater retardation of drug release in aqueous medium than directly compressed tablets. CASP showed greater suppression of drug release in aqueous medium than HWSP. Wet granulation HWSP-based matrix tablets coated to a final coat weight gain of ~25% w/w were optimized for chronodelivery of hydrocortisone in the colon. The optimized tablets exhibited a lag phase of ~6 h followed by accelerated drug release in the colonic region and have potential to control night time cortisol levels in patients with adrenal insufficiency.
Delay Induced Hopf Bifurcation of an Epidemic Model with Graded Infection Rates for Internet Worms
Authors: Zhao Tao , Bi Dianjie
Published: December 2017

A delayed SEIQRS worm propagation model with different infection rates for the exposed computers and the infectious computers is investigated in this paper. The results are given in terms of the local stability and Hopf bifurcation. Sufficient conditions for the local stability and the existence of Hopf bifurcation are obtained by using eigenvalue method and choosing the delay as the bifurcation parameter. In particular, the direction and the stability of the Hopf bifurcation are investigated by means of the normal form theory and center manifold theorem. Finally, a numerical example is also presented to support the obtained theoretical results.
Prognostic Value of New‐Generation Troponins in ST‐Segment–Elevation Myocardial Infarction in the Modern Era: The RUTI‐STEMI Study
Authors: Cediel Germán , Rueda Ferran , García Cosme , Oliveras Teresa , Labata Carlos , Serra Jordi , Núñez Julio , Bodí Vicent , Ferrer Marc , Lupón Josep , Bayes‐Genis Antoni
Published: December 2017

Background

In
ST
‐segment–elevation myocardial infarction (
STEMI
), troponins are not needed for diagnosis: symptoms and
ECG
data are sufficient to activate percutaneous coronary intervention. This study explored the prognostic value of new‐generation troponins in a real‐life cohort contemporarily treated for
STEMI
.

Methods and Results

We studied 1260 consecutive patients with primary
STEMI
treated with percutaneous coronary intervention between February 22, 2011, and August 31, 2015. We collected data on clinical characteristics and major adverse cardiovascular and cerebrovascular events (
MACCEs
) at 30 days and 1 year. Peak high‐sensitivity troponin T and sensitive‐contemporary troponin I levels were recorded.
MACCE
s occurred in 75 patients (6.1%) by day 30 and in 124 patients (10.8%) between day 31 and 1 year. A short‐term (0–30 days) multivariable Cox regression analysis revealed that age, Killip‐Kimball class, and left ventricular ejection fraction were independent predictors of
MACCE
s. In adjusted analysis, peak high‐sensitivity troponin T and sensitive‐contemporary troponin I were not significant (hazard ratio, 1.23 [95% confidence interval, 0.98–1.54] [
P
=0.071]; and hazard ratio, 1.15 [95% confidence interval, 0.93–1.43] [
P
=0.200], respectively). A long‐term (31 days–1 year) multivariable Cox regression analysis revealed that age, female sex, diabetes mellitus, prior coronary artery disease, Killip‐Kimball class, and left ventricular ejection fraction were statistically significantly associated with
MACCEs
. However, peak high‐sensitivity troponin T and peak sensitive‐contemporary troponin I were not significantly associated with
MACCEs
(hazard ratio, 1.03 [95% confidence interval, 0.88–1.20] [
P
=0.715]; and hazard ratio, 0.99 [95% confidence interval, 0.85–1.15] [
P
=0.856], respectively).

Conclusions

In the modern era, new‐generation troponins do not provide significant prognostic information for predicting clinical events in
STEMI
. We should reconsider the value of serial troponin measurements for risk stratification in
STEMI
.
The Ptolemaic–Roman Cemetery at the Quesna Archaeological Area*
Authors: Rowland Joanne
Published: December 2017

The 2007 season of the Minufiyeh Archaeological Survey commenced with a topographic survey at Quesna, and continued with the opening of two test trenches to evaluate the results of a magnetometry survey undertaken in 2006. These renewed investigations in 2007 were situated to the west of the mausoleum, and revealed burials of the Ptolemaic and Roman periods; these included simple pit burials, mud-brick burials, and ceramic coffins. The second trench was aimed at better understanding a rectangular structure adjoining the falcon necropolis in the west, and was successful in locating a multi-room mud-brick building with internal and external walls defined. The initial interpretation of this structure is that it served as an entrance building, originally with vaulted ceilings, which led beneath the ancient ground level and, it might be assumed, into the corridors of the falcon necropolis.
The Coffins of Iyhat and Tairy: A Tale of Two Cities*
Authors: Dodson Aidan
Published: December 2017

The publication of two coffins presently in the City Museum and Art Gallery in Plymouth, England. Dating to the Twenty-fifth Dynasty, they are interesting examples of inner coffins of their period, that of Tairy having an unusual arm arrangement. They also have an intriguing modern history, and an attempt is made to trace them from their first appearance at the Bristol Institution (ancestor of the modern City Museum & Art Gallery) in 1834, through the Bristolian private collection of mid-nineteenth century collector and traveller Thomas Pease (1816–1884), to their arrival in Plymouth in 1919.
A Bioarchaeological Perspective on Egyptian Colonialism in Nubia during the New Kingdom*
Authors: Buzon Michele R.
Published: December 2017

During the New Kingdom, Egypt began a military campaign to regain command over Nubia. Extremely successful, their control extended to the fourth cataract by the time of Thutmose III. The circumstances of this power, however, are not well known. It is unclear whether Egyptian colonists or locals administered Nubia during this time. Using a bioarchaeological approach via the study of human skeletal remains and archaeological data from the New Kingdom site of Tombos in Nubia and comparative Egyptian and Nubian skeletal samples, this paper addresses these long-standing questions. Analyses suggest that the Tombos individuals were an ethnically and biologically mixed group. The examination of health indicators suggests that the people of Tombos endured a relatively high degree of physiological stress, despite possible resources obtained through trade networks. Additionally, the Egyptianisation of Nubians at Tombos may have provided a peaceful environment in which few traumatic injuries were seen.
On the Presence of Deer in Ancient Egypt: Analysis of the Osteological Record*
Authors: Kitagawa Chiori
Published: December 2017

One of the topics of dispute concerning the animal world of Ancient Egypt is the presence (indigenous or introduced) of deer. Though depicted on several occasions in (pre)dynastic iconography, osseous remains of deer from archaeological contexts have been rare. Excavations at Qantir/Piramesse in the eastern Delta produced a comparatively large sample totalling 35 deer bones. Most finds date to the late Eighteenth and Nineteenth Dynasties. Both cranial and post-cranial skeletal elements are present, implying the presence of living deer near Qantir. Based on the size of these bone specimens the taxonomic status of the animals recorded from the eastern Delta during the second millennium BC has been verified. The results summarised here permit a reconsideration of the issue of the presence of deer in Ancient Egypt.
The Naos of ‘Bastet, Lady of the Shrine’ from Bubastis
Authors: Rosenow Daniela
Published: December 2017

Although the period of the Thirtieth Dynasty is characterised by conflicts between the peoples of the Mediterranean world and the Persians, Nekhtnebef (I) and Nekhthorheb (II) were able to implement an extensive building programme, which is reflected in construction work throughout Egypt. Bubastis in the Eastern Delta benefited from this programme: Nekhthorheb II renewed the rear part of the Great Temple of Bastet and — in the course of these building activities — dedicated a couple of granite shrines. Recently discovered shrine fragments from Tell Basta allow a reconstruction of the architecture and decoration of the naos of ‘Bastet, lady of the shrine’ in its original context: the naos was provided with an additional inner niche, whose socle was decorated with the icon of the ‘unification of the Two Lands’ and seems to have housed a processional image of Bastet. The shrine offers promising insights into a sphere which has not yet been satisfactorily studied.
A new fragmentary relief of King Ankhkheperure from Tell el-Borg (Sinai)?*
Authors: Ertman Earl L. , Hoffmeier James K.
Published: December 2017

Many questions surround the identity of the Amarna Period royal figures who succeeded Akhenaten. The recent discovery of an uninscribed fragmentary relief of one of these shadowy figures at Tell el-Borg, north Sinai, is treated in detail. On stylistic grounds, the image appears not to be that of Akhenaten or Tutankhamun, thus opening the door to the possibility that it is Ankhkheperure. This possibility is enhanced by the fact that the name of this elusive king was discovered on two wine-jar seal impressions found at Tell el-Borg.
Tell El-Amarna, 2008–9
Authors: Kemp Barry
Published: December 2017

This report on the 2008–9 seasons at Tell el-amarna mostly summarises the findings of excavations at the Stone Village and South Tombs Cemetery (where a second excavation area was begun), the study of the Christian remains around the tomb of Panehsy (no. 6), the results of a geophysical survey at the North City, and a programme of repairs carried out at the North Palace.
Falcon-Headed Coffins and Cartonnages*
Authors: Broekman Gerard P. F.
Published: December 2017

To date, six funeral ensembles containing falcon-headed mummy cases have been found. In this paper these funeral ensembles are discussed, in order to define the conceptual character of the falcon-headed mummy case, whether its occurrence was confined to a more or less limited period, and whether the falcon head on mummy cases was essentially a royal attribute.
The Delay of the Grain Ration and its Social Consequences at Deir El-Medîna in the Twentieth Dynasty: A Statistical Analysis
Authors: Antoine Jean-Christophe
Published: December 2017

Delay in the distribution of grain rations regularly occurred at Deir el-Medîna during the Twentieth Dynasty. In order to analyse the cause and social consequence of such delay, a statistical analysis of documents recording grain deliveries is presented, using both the delay and the absence of grain distribution, through an index specifically built for this purpose. Despite a complex circuit of cereals, organised to maintain an even grain supply, seasonal fluctuations are demonstrated by the analysis. These played an important role in the delay of grain distribution.
Lions, pylons, and feet: A small-scale linen shroud in the Bolton Museum and Art Gallery
Authors: Riggs Christina
Published: December 2017

Publication of a Roman Period shroud (BOLMG 1983.1.99) formerly in the Wellcome and Hilton Price collections. The decoration of the shroud combines iconographic elements related to the foot area of the mummy.
A particular form of Amun at Deir el-Medina: Amun-Re n 3b.t jmn or Amun-Re n 3b.(w)t Jmn?
Authors: Toye Nathalie
Published: December 2017

This article discusses a form of Amun unknown outside Deir el-Medina and attested by only one document, stela BM EA 812, which has been published but lacks detailed study. The name of this exceptional form of Amun has been read incorrectly and confused with another more classical epithet. Even if some doubts persist concerning the translation and the understanding of this designation, it appears that it refers to a particular local form of Amun probably honoured in one of the numerous chapelles de confrérie of the village.
Die Lokalisation der ‘5 Mauern’/Wachposten (t3 5 jnb.t/n3 jnb.wt/t3 jnb)
Authors: Dorn Andreas
Published: December 2017

The living area of the workmen from Deir el-Medina was limited by the ‘5 walls’/guard posts, the location of which has not yet been demonstrated. The expression sš/snj t3 5 jnb.t ‘passing the 5 walls/guard posts' opens up the possibility of determining five spots in Western Thebes which allow the complete separation of the royal necropolis of the New Kingdom. This was the main function of the ‘5 walls’/guard posts. A list of the known attestations of the ‘5 walls’/guard posts is provided in the appendix.
Topical PDGF-BB results in limited healing in a patient with Werner’s syndrome and chronic leg ulcers
Authors: Wollina U. , Gruner M. , Koch A. , Köstler E. , Hubl W. , Hanson N.B. , Oshima J.
Published: December 2017

Werner’s syndrome is a rare premature ageing syndrome caused by mutations in the WRN gene. The disease spectrum shows sclero edematous skin changes, with chronic ulcerations, cutaneous wound-healing impairment and calcification. Juvenile cataract, arteriosclerosis, a higher risk of malignancy and diabetes mellitus are also often found.
The importance of pain reduction through dressing selection in routine wound management: the MAPP study
Authors: Meaume S. , Téot L. , Lazareth I. , Martini J. , Bohbot S.
Published: December 2017

Objective:

To discover the incidence of pain in patients with acute or chronic wounds of various causes during dressing removal, and the effect of switching to a non-adherent dressing.

Method:

A total of 656 primary care physicians reported the relevant details of all acute or chronic wounds observed during routine visits throughout the study period. The pain experienced during dressing changes was systematically evaluated. In patients with moderate to severe pain, a more extensive evaluation was performed and they were invited to complete a self-evaluation questionnaire. If the patients were seen at a subsequent visit, a new evaluation was performed.

Results:

In total 5850 patients were seen: 2914 with acute wounds and 2936 with chronic wounds. During dressing changes, a similar number of patients with acute and chronic wounds reported ‘moderate to severe’ pain during the medical screening visit (79.9% and 79.7%) and ‘very severe’ pain in their self-evaluation questionnaire completed at home (47% and 59% respectively). Dressing removal was most painful when there was adherence to the wound bed. Switching to a new, non-adherent dressing reduced pain during dressing changes in 88% of patients with chronic wounds and 95% of patients with acute wounds.

Conclusion:

This study demonstrates that similar problems with patient acceptability arise irrespective of wound aetiology. Pain is a major problem and is most often related to dressing selection. Selecting a suitable, non-adherent dressing improves patient acceptability.

Declaration of interest:

This study was sponsored by Laboratoires Urgo.
Priority Monism Beyond Spacetime
Authors: Le Bihan Baptiste
Published: December 2017

I will defend two claims. First, Schaffer’s priority monism is in tension with many research programs in quantum gravity. Second, priority monism can be modified into a view more amenable to this physics. The first claim is grounded in the fact that promising approaches to quantum gravity such as loop quantum gravity or string theory deny the fundamental reality of spacetime. Since fundamental spacetime plays an important role in Schaffer’s priority monism by being identified with the fundamental structure, namely the cosmos, the disappearance of spacetime in these views might undermine classical priority monism. My second claim is that priority monism can avoid this issue with two moves: first, in dropping one of its core assumption, namely that the fundamental structure is spatio-temporal, second, by identifying the connection between the non-spatio-temporal structure and the derivative spatio-temporal structure with mereological composition.
Instructor interactivo de nivelación diferencial (IIN) en ingeniería topográfica: diseño, desarrollo y evaluación
Authors: Garbanzo León Jaime , Lara Morales Gustavo
Published: December 2017

Este estudio describe cómo se desarrolló y probó un simulador web prototipo para apoyar el proceso de aprendizaje de los equipos y de los cálculos para la enseñanza de la nivelación diferencial (ND) en Ingeniería Topográfica. Tradicionalmente, la formación de este proceso de aprendizaje se imparte en campo abierto y a un estudiante a la vez. Estas situaciones hacen que la enseñanza sea lenta y que los estudiantes no obtengan suficiente práctica. Se desarrolló un simulador web con los lenguajes JavaScript, PHP y MySQL para ayudar en el proceso de aprendizaje. Además, se agregó la capacidad de guardar estos datos para un análisis más detallado. Se tomaron dos grupos de topografía básica: el grupo de estudio (utilizó la aplicación) y el grupo de control (no la utilizó). Se realizaron dos tipos de evaluaciones: una encuesta de opinión sobre la aplicación y una comparación entre los resultados de los grupos de control y estudio en la primera práctica de campo con instrumentos de ND. El simulador recibió una calificación alta en las encuestas. Por su parte, el grupo de estudio obtuvo mejores resultados en la práctica de campo de ND que el grupo de control. Se concluye que los resultados sugieren una mejora en el desempeño del estudiante en las prácticas de campo cuando se utiliza el simulador de ND; sin embargo, se debe someter a una mayor cantidad de estudiantes con el fin de consolidar más significativamente los resultados.
Modelos de financiación de la educación superior estatal: El caso de la Universidad de Costa Rica
Authors: Araya Leandro Carlos
Published: December 2017

En el presente artículo se analiza el modelo de financiación de la educación superior estatal en Costa Rica. Como resultado, de la difícil situación económica por la que atraviesan la mayoría de países del mundo y de una mayor demanda por educación superior, en los últimos años se han desarrollado diversos modelos para el financiamiento de la educación superior pública estatal. En el caso particular de Costa Rica, en años recientes, el Estado ha apostado por una mayor participación en el financiamiento de la educación en todos sus niveles. Bajo este contexto, el presente artículo pretende analizar el modelo de financiación de la educación superior pública estatal vigente en Costa Rica, en general, y en la Universidad de Costa Rica, en particular. El estudio desarrollado es de carácter descriptivo; para tal efecto, se ha procedido a realizar una búsqueda de datos cuantitativos, cualitativos y normativos que permitan hacer un recuento del desarrollo del modelo de financiamiento vigente y de sus principales características. Con respecto a esta materia, es poco lo que se ha publicado en el país, de manera que el estudio llena un vacío al sistematizar información dispersa para el análisis de un tema de alta relevancia en las políticas públicas costarricenses. En este sentido, la doble reforma del artículo 78 de la Constitución Política en 1997 y 2011, que obliga al Estado a invertir en educación, en primera instancia un 6% del Producto Interno Bruto (PIB) y posteriormente el 8% de ese indicador, ha permitido que el presupuesto de las universidades estatales costarricenses se haya incrementado de manera considerable y sostenida, pues pasa de representar el 0,80% del PIB en 1999 a un 1,42% en 2017.
Metodología para valorar y clasificar herramientas de evaluación de accesibilidad web
Authors: López Zambrano Javier Hernán , Moreira Pico Ramón Joffre , Alava Cagua Nathaly Valeria
Published: December 2017

Teniendo en cuenta que la accesibilidad Web es el arte de garantizar que los portales Web puedan ser visitados y utilizados de forma satisfactoria por el mayor número posible de personas, es imprescindible evaluar los contenidos Web empleando las herramientas adecuadas, por tal razón, este trabajo de investigación tiene como objetivo presentar un modelo metodológico para valorar estas herramientas automáticas, y seleccionar entre las existes, las que mayor número de criterios (contemplados en la WCAG 2.0) pueda evaluar. El modelo propuesto comprende una metodología cíclica y se la denomina IPAC por las siglas en inglés de sus 4 etapas (Inspect-Plan-Assess-Categorize), las mismas que pretenden categorizar y/o recategorizar las herramientas de evaluación de accesibilidad Web, cuyas funciones incorporadas son cambiantes en el tiempo. La validación realizada en julio de 2017 de este modelo dio como resultado la categorización de las 5 mejores herramientas de licencia libre por cada nivel de conformidad (A, AA y AAA).
Efeito Residual e Reaplicação de Boro na Cultura do Eucalipto
Authors: Celestrino Thiago de Souza , Buzetti Salatiér , Nakayama Fernando Takayuki
Published: December 2017

É importante verificar se a aplicação de boro (B) realizada inicialmente é suficiente para atender as exigências da cultura ao longo do ciclo, ou se é necessária a reaplicação do elemento em cobertura. Sendo assim, o objetivo do trabalho foi avaliar a altura de planta, o diâmetro a altura do peito (DAP), volume total de madeira com casca de eucalipto, teor de B no solo e concentração deste no folhedo, em função do efeito residual de fontes de B e da aplicação foliar do micronutriente, assim como a reaplicação do elemento em cobertura. O delineamento experimental foi de blocos casualizados, com tratamentos dispostos em esquema fatorial de 3x2x2 em parcelas subdivididas, sendo: 0 kg ha-1 de B; 1 kg ha-1 de B utilizando o fertilizante borogran (baixa solubilidade, 10% B) e 1 kg ha-1 de B utilizando o fertilizante ácido bórico (alta solubilidade, 17% B), ambos sendo aplicado manualmente em filete contínuo no sulco de plantio. O fatorial 2 se refere à aplicação ou não de B via foliar. A parcela subdividida em 2 se refere às subparcelas que receberam ou não a reaplicação de B aos 34 e 46 meses após o plantio, na dose de 1 kg ha-1 de B, cada, utilizando o fertilizante ácido bórico. As reaplicações de B em cobertura propiciaram maiores teores do elemento no solo; logo, houve efeito benéfico para o incremento no DAP e, consequentemente, volume de madeira com casca.

PALAVRAS-CHAVE: Solubilidade, cerrado, micronutriente
A classificação biológica: uma aula a partir do diálogo entre a cultura indígena e a história da ciência
Authors: Santos Ana Flavia Dos , Souza Ellen Gonzaga Lima , Nascimento Junior Antonio Fernandes
Published: December 2017

Mediante as diversas problemáticas no ensino de ciências e na aprendizagem em geral, muitos estudos tem procurado investigar: quais as perspectivas que podem colaborar para construção de um ensino realmente significativo. Sendo assim, o trabalho tem por objetivo analisar os resultados de prática pedagógica diferenciada aplicada para professores em formação inicial e continuada, de forma a verificar se a uma nova perspectiva pode ser apreendida e utilizadas pelos mesmos no seu dia-a-dia escolar. A atividade foi executada no formato de um Minicurso formativo, utilizando a História da ciência e mitologia indígena para construir um caminho sobre a classificação dos seres vivos, percorrendo as épocas históricas mais discutidas atualmente. Após a execução da atividade prática, os participantes realizaram analises escritas sobre o procedimento, colocando suas perspectivas e impressões sobre a pratica. As falas foram analisadas de acordo com a categorização de Analise de conteúdo qualitativo, onde foi verificada a viabilidade do trabalho executado. As analises foram discutidas evidenciando os resultados da pratica.

PALAVRAS CHAVE: Ensino de Biologia, Classificação Biológica, Interdisciplinaridade.
De entrave à potencialidade: Análise e diretrizes ecológicas para o Parque do Povo e do Córrego do Veado em Presidente Prudente- SP
Authors: Pereira Talita Rezende Torcato , Luiz Fellipe Sambinelli , Meneguetti Karin Schwabe
Published: December 2017

O descuido com o meio ambiente e a falta de planejamento ambiental integrado com o planejamento urbano promovem desequilíbrios ambientais e, até mesmo, desastres naturais. As cidades atuais têm promovido o desenvolvimento urbano desassociado das questões ambientais, tratando sua base natural como entrave para o crescimento. Desta forma, o presente artigo tem como finalidade analisar a situação atual do Parque do Povo e o Córrego do Veado como possíveis potencializadores para a formação de uma estrutura ecológica para a cidade de Presidente Prudente-SP. Busca-se entender qual a importância de ambos para a cidade, seja no seu tipo de ocupação ou como são tratados na questão na visão do planejamento ambiental. Por meio de levantamentos bibliográficos, visitas in loco, e discussões, foi constatado a necessidade de propostas alternativas para o Parque do Povo e para o córrego do Veado, propagando-as para a cidade e configurando-como ponto de partida para a implantação de uma estrutura ecológica para a cidade de Presidente Prudente-SP. Apresentam-se diretrizes projetuais para que a área possa interagir com os processos naturais e prevenir inundações que já se tornaram frequentes.

PALAVRAS-CHAVE: Córrego Veado; Estrutura Ecológica; Parque do Povo; Presidente Prudente, SP.
Quantificação dos depósitos da pulverização em função da técnica de aplicação na cultura da soja
Authors: Omoto Pedro Hideki , Tomaz Rafael Simões , Prado Evandro Pereira
Published: December 2017

O conhecimento e uso da melhor técnica de aplicação de defensivos podem maximizar a eficiência de controle e reduzir contaminação ambiental. O trabalho teve como objetivo avaliar o desempenho de pontas de pulverização (jato cônico – TXA 8002 VK, plano duplo – TTJ 60 11002, plano com indução de ar – AIXR 110025, plano duplo de deriva reduzida – DGTJ 11002 e jato plano de faixa ampliada – XR 8003) sobre os depósitos da pulverização em três partes de amostragem das plantas de soja (superior, mediano e inferior) nos estágios V7-8 e R3. O ensaio foi realizado na Faculdade de Ciências Agrárias e Tecnológicas - UNESP - Câmpus de Dracena. Para detecção dos depósitos da pulverização foi realizada a aplicação do corante alimentício Azul Brilhante na concentração de 1500 mg L-1. Valores médios dos depósitos foram submetidos à análise de variância em esquema fatorial e as médias comparadas pelo teste de Students (LSD) a 5% de probabilidade. As frequências acumuladas dos dados originais de deposição foram adequadamente ajustadas segundo modelo de Gompertz. No estádio de desenvolvimento V7-8 a ponta de pulverização que proporcionou maior valor de deposição nas plantas de soja foram TTJ 60, DGTJ 11002 e XR 8003. Na segunda aplicação (R5), as pontas de pulverização que proporcionaram os maiores valores de deposição nas plantas de soja foram AIXR 110025, TXA 8002 e DGTJ 110025. Maiores valores de uniformidade nas folhas da parte mediana das plantas foram verificadas pela ponta DGTJ 11002 nos estágios V7-8 e R5.
Palavras-chave: deposição da pulverização, tecnologia de aplicação, pontas hidráulicas.
The Logic of the Euro, Its Institutional Architecture and the Related Implications
Authors: Savona Paolo
Published: December 2017

The Euro is the logical consequences of the European common market according to the principle ‘one market, one money’, to avoid unfair competitionchanging internal monetary parities. Anyhow it is a necessary but insufficient condition being the institutional architecture weak. The European Central Bank cannot perform as the other main central banks: cannot act as lender of last resort or intervene on the exchange market to counteract speculation; the risks on national exchange rates has been transferred to member-countries sovereign debts withouta non-deflationary solution to reenter the excesses in theagreed ratio on GDP. The Eurozone is a non-optimal currency area without a policy Mundell’s type. The suggested solutionsby the Europeans are to reform national labor markets and public bureaucracies, and by the idealists to create a political union.
Implementing Relationship Banking Strategies and Techniques and Improving Customer Value
Authors: Guo Yongsheng
Published: December 2017

This paper identifies strategic concepts and practical techniques in relationship-banking andexploreshow customer value was improved and how relationship-bankingperformancewas measured and linked to relationship managers’ compensation.  Grounded theory was adopted to collect and analyse data. 25 interviews have been conducted with relationship managers and corporate banking directors in 11 case banks and case banks’ quantitative data was used to support the propositions. It was found that customer relationship was seen as a valuable asset. Relationship Orientation and Customer Focus were evaluated by undertaking internal surveys and relationship management objectives were formulated and actions were proposed to improve Customer Value to the case banks. In the case banks Customer Information was collected through multiple customer touch points and integrated and analyzed.Customer Knowledge wasaccumulated and sustainable Competitive Advantages were built.Customer Perception and Customer Loyalty were measured externally.Customer Value and Risk Adjusted Return on Asset (RAROA) wereemployed to measure relationship banking performance and reward relationship managers accordingly. The interviewees perceived that relationship-banking performance could be improved in this dynamic learning process. 
STUDY ON MACROZOOBENTHOS COMMUNITY IN THE WATERS OF THE RIVER AIR PERIKAN MUNICIPALITY OF PAGAR ALAM SOUTH SUMATRA
Authors: Tampubolon Rafles , Hanafiah Zazili , Junaidi Endri
Published: December 2017

The research entitled “ Study on Macrozoobenthos Community in the Waters of the River Air Perikan Pagar Alam Municipality”, was conducted from November 2007 until March 2008. The aims of the research: to know about composition, density, diversity index, dominancy index, and similarity index, which based on the different microhabitat types. Sampling was carried out on November 2007. Five sampling stations were determined by survey method  and the Purposive Sampling method was used at each sampling point to find stony, gravel, sandy and leaf pack area as a different microhabitat substrate. Twenty one orders (Ephemeroptera, Trichoptera, Diptera, Plecoptera, Collembola, Hemiptera, Odonata, Coleoptera, Lepidoptera, Megaloptera, Hymenoptera, Orthoptera, Decapoda, Plesiopora, Tricladida, Amphipoda, Isopoda, Mesogastropoda, Ctenobranchiata, Eulamellibranchiata, and Rhynchobdellida) which are consisted of 70 families and 151 genera were identified from four types of substrates on each sampling station. According to this research, station 4 has the highest in composition (80 genera), and the lowest one at station 1(33 genera). The highest abundance was 12589 ind./m2  found in the station 5, and the lowest one was in the station 1 approximately 880 ind./m2. For the diversity index value, station 3 was the highest (3.1) and the lowest one was station 5 (1.9). The Dominancy index was found in station 5 at the sandy substrates was  approximately 0,8 index, which dominated by Tubifex sp. There were  differences species composition  on each station. Keywords : Macrozoobenthos, community, the river Air Perikan.
PRODUKTIVITAS PERIKANAN TUNA LONGLINE DI BENOA (STUDI KASUS: PT. PERIKANAN NUSANTARA) (Tuna Lingline Fisheries Productivity in Benoa (Case study: PT. Perikanan Nusantara))
Authors: Nugraha Budi , Hufiadi .
Published: December 2017

ABSTRACT
Tuna longline fishery in Indonesia has grown since 1972. With the increasing number of tuna longline vessels operating in Indonesian waters, there are needs to research on the productivity of these vessels, especially vessel owned by PT. Perikanan Nusantara as a case study in this research. Data collected through the research activities at the Port of Benoa from March to November 2011. Overall annual production of tuna longline catches PT. Perikanan Nusantara fluctuated during the years 1999-2009 where the average production of fish caught tuna longline vessels size 60 GT per year amounted to 161.19 tons, 40 GT of 231.18 tons and 15 GT of 34.50 tons. Seen from the catch ability of tuna longline per set during the year 2010, found that overall, the average catch per settings for vessel size of 40 GT is higher than the vessel size of 15 GT and 60 GT. Based on the value of the tuna hook rate for vessels size of 15 GT are 0.3, vessels 40 GT are 0.25 and 60 GT are 0.38.
Key words: production, productivity, hook rate, tuna longline

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ABSTRAK

Perikanan tuna longline di Indonesia telah berkembang sejak tahun 1972. Seiring dengan pertambahan waktu, telah terjadi peningkatan jumlah kapal tuna longline yang beroperasi di perairan Indonesia. Oleh karena itu perlu adanya penelitian mengenai produktivitas dari kapal-kapal tersebut, terutama kapal milik PT. Perikanan Nusantara sebagai studi kasus dalam penelitian ini. Pengumpulan data dilakukan melalui kegiatan penelitian di Pelabuhan Benoa dari bulan Maret hingga November 2011. Produksi tahunan keseluruhan hasil tangkapan tuna longline PT. Perikanan Nusantara selama tahun 1999-2009 berfluktuatif dimana produksi rata-rata ikan hasil tangkapan kapal tuna longline berukuran 60 GT per tahun sebesar 161,19 ton, kapal berukuran 40 GT sebesar 231,18 ton dan kapal berukuran 15 GT sebesar 34,50 ton. Dilihat dari daya tangkap tuna longline per setting selama tahun 2010, diperoleh bahwa secara keseluruhan rata-rata tangkapan per setting untuk kapal berukuran 40 GT lebih tinggi dibanding armada berukuran 15 GT dan 60 GT. Berdasarkan nilai hook rate terhadap ikan tuna untuk kapal berbobot 15 GT diperoleh rata-rata hook rate 0,3, kapal 40 GT 0,25 dan hook rate kapal berbobot 60 GT sebesar 0,38.

Kata kunci: laju pancing, produksi, produktivitas, tuna longline,
PENGUATAN CAHAYA PADA BAGAN MENGGUNAKAN REFLEKTOR KERUCUT SEBAGAI UPAYA MENINGKATKAN HASIL TANGKAPAN CUMI-CUMI (Light Strengthening on Lift Net with Conical Reflectors to Squid Catch Improvement)
Authors: Ahmad Supriono , Puspito Gondo , Sondita M. Fedi A. , Yusfiandayani Roza
Published: December 2017

ABSTRACTStudy of light strengthening on lift net with conical reflectors was conducted in Kao Bay waters. Three units of lift net were operated 14 nights at the full moon condition. Every lift nets were completed with three different kind of lamp cover, called tudung, reflector αr23,3o and αr32,6o. Fishing operation time of lift net were divided into two intervals of time i.e 20.00-01.00 and 01.00-05.00 WIT (East Indonesian Timezone). Total yield of lift net with reflector αr23,3o was 5.774 kg (41,45%), while that of the lift net with reflector αr 32,6o was 4.977 kg (35,72%), and that of total yield of the lift net with tudung was 3.180 kg (22,83 %). Fishing operation time of lift net at 01.00-05.00 WIT (East Indonesian Timezone) produced 12.661 kg (91 %) weight of total catch, higher than fishing operation of lift net at 20.00-01.00 am that produced 1.270 kg (9 %) weight of total catch. However, statistical analysis concluded that design of the reflector did not significantly affect the catch per trip (Pvalue > 0,05) while fishing time significantly affected the catch per trip (Pvalue < 0,05).Key words: Kao Bay, light, reflector, squid-------ABSTRAKPenelitian tentang pengaruh penguatan cahaya pada bagan dengan reflektor kerucut terhadap hasil tangkapan cumi-cumi dilakukan di perairan Teluk Kao. Tiga unit bagan dioperasikan selama 14 malam pada saat kondisi terang bulan. Masing-masing bagan dilengkapi penutup lampu berbeda, yaitu tudung standar, reflektor kerucut αr23,3o dan αr32,6o. Setiap pengoperasian bagan dibagi dalam dua interval waktu, yaitu antara 20.00-01.00 WIT dan 01.00-05.00 WIT. Hasil penelitian menunjukan bahwa penggunaan reflektor αr23,3o memberikan hasil tangkapan cumi-cumi paling banyak dengan bobot total 5.774 kg (41,45%), sedangkan bagan dengan reflektor αr32,6o seberat 4.977 kg (35,72%), dan bagan dengan tudung 3.180 kg (22,83%). Pengoperasian bagan pada interval waktu penangkapan 01.00-05.00 WIT menghasilkan bobot tangkapan 12.661 kg (91%), atau lebih tinggi dari interval waktu penangkapan 20.00-01.00 WIT (1.270 kg) atau 9% dari total hasil tangkapan. Namun hasil uji statistik menyimpulkan bahwa faktor tudung tidak berpengaruh nyata terhadap tangkapan cumi-cumi per trip sedangkan faktor interval waktu penangkapan berpengaruh nyata (Pvalue = 0,05).Kata kunci: Teluk Kao, cahaya, reflektor, cumi-cumi
Protocol for Management of Hyperthyroidism by Radioactive Iodine (RAIT)-SNMB Guidelines
Authors: Begum Fatima , Sultana Sadia , Nahar Nurun , Alam Faridul , Hasan Mizanul , Hussain Raihan , Haque Mahmubul , Nasreen Faria , Khan Mohafizul Haque , Nisa Lutfun , Moslem Fauzia , Afroz Shahana , Quadir Kamila Afroj , Karim MA
Published: December 2017

Abstract not availableBangladesh J. Nuclear Med. 18(1): 85-88, January 2015
De Cuneo à Perinetti. Influences de l’art européen en Amérique du sud : la réplique d’un peintre uruguayen
Authors: Cardis Régine
Published: December 2017

C’est dans la peinture de paysage que José Cuneo (1887-1977) projette l’essentiel de ses ambitions esthétiques. Il peint la campagne uruguayenne dans un style appelé « planismo », qui tente d’assumer l’héritage coloriste de la peinture impressionniste et postimpressionniste, ainsi que l’orientation constructive et formelle des héritiers de Cézanne. La découverte de l’œuvre de Soutine l’oriente vers une expression qui prend en compte le mouvement et la libre interprétation du monde visible. Dans la série des « Ranchos y Lunas », il adapte une conception spatiale héritée de Soutine à une vision panthéiste et métaphorique du paysage local. Âgé de 70 ans, Cuneo-Perinetti expérimente l’abstraction en procédant à l’examen rétrospectif de sa propre évolution affective et mentale.
Art Madí (1944-1948) : le compas, la parole poétique et l’utopie
Authors: Tennenini Roberta
Published: December 2017

En 1944, l’apparition de la revue Arturo marque le commencement d’un art non figuratif proprement latino-américain. En signalant les antécédents artistiques régionaux et internationaux et en montrant le contexte historique mondial dans lequel émerge le mouvement Madí, cet article propose une analyse de sa valeur culturelle et de ses enjeux esthétiques en même temps qu’il permet de saisir l’originalité de la contribution du Río de la Plata à l’évolution de l’art abstrait contemporain.
Clemente Padín, la subversion du mot et de l’objet
Authors: Lespes Munoz Elena
Published: December 2017

Durant les années 1960 et 1970, nombre de pays d’Amérique du Sud sont gouvernés par des dictatures militaires. Dans ce contexte politique qui a de profondes répercussions sur la vie sociale et culturelle, les artistes sont amenés à repenser leurs pratiques. La perte de confiance dans les institutions culturelles, la remise en cause des formes traditionnelles de l’art et la nécessité de se confronter au réel apparaissent comme des enjeux fondamentaux. Cet article présente ces bouleversements au travers de l’œuvre de l’artiste uruguayen Clemente Padín.
Article Commentary: Molecular Targets of Breast Cancer: AKTing in Concert
Authors: Basu Alakananda
Published: December 2017

Despite significant advancement in the diagnosis and treatment of breast cancer, many patients succumb to this disease. The elucidation of aberrant signaling pathways that lead to breast cancer should help develop more effective therapeutic strategies. The Akt signaling pathway plays an important role in the development and progression of breast cancer. Overexpression/activation of Akt has been associated with poor prognosis and resistance to hormonal and chemotherapy. Although mutations in Akt are rare in breast cancer, the activity of Akt is regulated by hormones, growth factors, growth factor receptors, oncogenes and tumor suppressor genes that are often deregulated in breast cancer. The objective of this commentary is to discuss recent literature on how activation of Akt by various signaling pathways contributes to breast cancer and confers resistance to current therapy.