bluuebunny/crossref_metadata_2025 huggingface dataset:
Dry Matter Production of Two Rice Cultivars with Contrasting Root Plasticity Expression Under Different Topographic Conditions Subjected to Soil Moisture Fluctuation
Authors:   Graduate School of Bioagricultural Sciences, Nagoya University, Japan, Owusu-Nketia Stella , Rodriguez Suralta Roel , Inukai Yoshiaki , Mitsuya Shiro , Kano-Nakata Mana , Amoako Ofori Peter , Ngoc Nguyen Dinh Thi , Yamauchi Akira ,   Department of Crop Science, School of Agriculture, College of Basic and Applied Sciences, University of Ghana,   DA-Crop Biotechnology Center, Philippine Rice Research Institute (PhilRice), Maligaya, Science City of Muñoz, Nueva Ecija 3119, Philippines,   International Center for Research and Education in Agriculture, Nagoya University, Japan,   Biotechnology Center, College of Basic and Applied Sciences, University of Ghana,   Faculty of Agronomy, Vietnam National University of Agriculture, Hanoi, Vietnam
Published: April 2024

In rainfed lowland rice fields characterized by sloping terrains and the presence of a hardpan in a flat topography, plants are often exposed to soil moisture fluctuation (SMF) stress due to erratic rainfall patterns. Root plasticity is one of the key traits that play important roles in plant adaptation under such conditions. In this study, two contrasting genotypes, KDML105 and IRAT109, were examined to quantify the expression of plasticity in root branching at different positions in the toposequence (TP) and in a flat topography with a hardpan, both without a groundwater table, and subjected to SMF. Results showed that KDML105 exhibited improved adaptation to SMF conditions due to its greater root system because of the promoted nodal root production and development of lateral roots in the upper soil layer (0 – 20 cm soil depth) along the TP and above the hardpan in a flat topography, which led to the maintenance of its stomatal conductance and dry matter production. IRAT109, on the other hand, did not express root plasticity in deep-rooting due to the absence of groundwater table, particularly in the upper TP, as well as branching ability above the hardpan in a flat topography, which resulted in less water uptake and reduced dry matter production under SMF. Overall, the results indicated that root plasticity in the upper soil layer could be an important trait for the adaptation of rice, both in a sloping TP without a hardpan or in a flat topography with a hardpan, experiencing SMF.
Angiotensin I-Converting Enzyme Inhibitory and Antioxidative Activities of the Bioactive Peptides in the Crude Salt-Soluble Protein Hydrolysates of Pili Nut (Canarium ovatum Engl.) cv. Mayon Kernel
Authors:   The Marine Science Institute, Velasquez St., University of the Philippines Diliman, Quezon City 1101, Philippines, Gamba Ella Mae , Uy Lawrence Yves , Torio Mary Ann ,   Southeast Asian Regional Center for Graduate Study and Research in Agriculture, College, Los Baños, 4031, Laguna, Philippines,   University of the Philippines Los Baños, College, Los Baños, 4031, Laguna, Philippines,   German Academic Exchange Service (DAAD), Postfach 200404, D-53134 Bonn, Germany
Published: April 2024

The in silico enzyme digestion and peptide function annotation of pili nut (Canarium ovatum Engl.) 11S globulin protein sequence revealed the presence of bioactive peptides with antihypertensive and antioxidative activities. Molecular docking simulations showed that the proline-histidine (PH) ligand can better inhibit angiotensin I-converting enzyme (ACE) activity than captopril. This result was verified through biochemical assays. Pili kernel protein was extracted with 0.5 M NaCl buffer using the modified Osborne fractionation method, which yielded 100 mg of protein per gram of defatted pili kernel determined via Bradford assay. SDS-PAGE suggested that the protein extract had a major legumin-like (11S) globulin structure with an approximately 57 kDa molecular weight. Enzymatic hydrolysis using pepsin, thermolysin, α-chymotrypsin, and trypsin was used to release the potential antihypertensive and antioxidative peptides with an average rate of 0.03869 mm2 h-1, estimated from band intensity. The hydrolysates were tested for ACE inhibition and free radical scavenging. Captopril and enalapril had %ACE inhibitions of 74.02 and 83.57 %, respectively, whereas the 6 h hydrolysates had a peak %ACE inhibition of 99.73%. These same hydrolysates however, only had 51.32% 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity compared to ascorbic acid, which had 75.59%. These results showed the potential of pili nut as a functional food, especially for preventing high blood pressure and other cardiovascular diseases.
A Review and Critical Analysis of Transgender Persons Act 2018; Is Pakistan Consciously Protecting LGBQ Movement?
Authors: Ashna Rehman  , Maqbool Ahmad
Published: April 2024

Rallies in solidarity with women experiencing various sorts of violent assault in Pakistan's underprivileged areas have increased dramatically. Such demonstrations are known as "Aurat Marches," and they began with the widely famous slogan "Mera jism meri marzi." At first glance, the tagline stressed the significance of female consent. However, different people interpreted the slogan differently, and some supporters of the campaign understood freedom in such a way that they defended LGBTQ people in the process.  As a result, amid a critical women's rights movement, the agenda being defended has already shifted from a fight for women's empowerment to an endeavor to legitimize LQBTQ people. Even though the lines are so clear, the semantic obfuscation contained in the Transgender Protection Act 2018 has already offered a noticeable attempt to conceal the LGBTQ in the name of preserving the rights of transgenders. The goal of this study is to look into the relationship between homosexuality, LGBT, and the Transgender Protection Act of 2018.  The author used cross-sectional analysis to determine that, according to sections 2 and 3 of the statute above, anyone can pick any gender based on their feelings, with no legal or medical checks and balances required. The issue must be effectively addressed before its adverse medical, psychological, and social effects pose irreversible damage to the community. However, the author does not shy away from discussing the different obstacles that the transgender community faces and seeks to propose solutions for their social and economic well-being.
Dissolution of Marriage: Exploring Various Modalities of Ending Marriage in Islamic Law
Authors: Ali Haseeb , Hussain Aftab , Islam Muhammad , Azeem Hafiz Muhammad
Published: April 2024

The purpose of this paper is to familiarize readers with the various methods of divorce in Islamic law. Divorce, according to the Holy Prophet (SAW), is the worst of the things permitted by law. Divorce is an evil that should be avoided as much as possible. However, in some cases, this evil becomes a necessity, because when the parties to the marriage are unable to carry on their union with mutual affection and love, it is preferable to allow them to separate rather than compel them to remain together in a state of animosity and apathy. The author also aims to provide a thorough explanation of the broad notion of divorce in Islam by methodically classifying it according to its effectiveness and structure. Furthermore, it seeks to clarify the rights granted to the husband and wife in the event of a divorce. All of the different aspects of divorce will be carefully covered in separate sections so that readers can grasp the subject completely.
Implications of Large Language Models in Medical Education
Authors: Fan Ka
Published: April 2024

This paper explores the potential of LLMs, like ChatGPT and Bard, in revolutionising medical education. Trained on vast medical datasets, these AI models can answer questions, explain complex concepts, and even generate exams. Studies show promising performance on medical licensing exams, highlighting their potential as valuable learning tools. The paper discusses how LLMs can support students by simplifying concepts, simulating patient interactions, and personalising learning. Additionally, it explores how LLMs can streamline exam creation for educators. However, limitations exist, including the inability to handle complex reasoning and the risk of perpetuating errors from training data. Overall, the paper argues that LLMs, despite limitations, are a powerful tool for the future of medical education, offering interactive learning experiences and personalised support for future healthcare professionals.
The effectiveness of teaching and learning strategies used by teachers in Sulu State College
Authors: Adidul Sharisma
Published: April 2024

In order to ascertain the efficacy of the instructional and educational methods that are utilized by instructors at Sulu State College, the study employed a purposive sampling method to select a sample of 100 teachers from various departments of the institution. This study provides valuable insights into the effectiveness of teaching and learning strategies employed by instructors at Sulu State College. The findings highlight the importance of implementing effective strategies to promote student success in higher education and the possibility of improving teaching practices and increasing student involvement, which will ultimately contribute to enhanced learning outcomes at Sulu State College and broader educational institutions.
Evaluation de l’équilibre glycémique chez les sujets âgés présentant un diabète de type 2
Authors: Diouf NN , Boye O , Soumboundou M , Guèye MW , Sawaré EM , Sylla-Niang M
Published: April 2024

Introduction. To investigate glycemic control in type 2 diabetics aged monitored at the medical laboratory of general hospital of Grand-Yoff (Dakar, Senegal). Materials and methods. This is a retrospective study conducted at the medical laboratory of general hospital of Grand-Yoff (Dakar, Senegal) from November 1, 2011 to May 31, 2012. All patients with type 2 diabetes diagnosed and regularly followed for more than 6 months, taking oral medications for more than 6 months and have made biological analysis were included. Patients were divided into 2 groups: Group G consists of subjects aged 60 years and older and group T subjects less than 60 years of age. Results. In this study, 80 type 2 diabetic subjects were included, 50 in the G group. Subjects in G group were composed of 13 men and 37 women. Their average age was 67.36 ± 5.67 years. The average rates of the hemoglobinA1c were higher in patients in G group than in T group with a statistically significant difference (p = 0.03) and duration of diabetes (p = 0.001). Half of the subjects in G Group (n = 25) has a hemoglobinA1c greater than 8%. Conclusion. Regular assessment of glycemic control should be a key element in monitoring type 2 diabetes aged to prevent the occurrence of complications.
Apport de la cytoponction dans le diagnostic des nodules thyroïdiens au CHU d’Antananarivo
Authors: Rakotoarisoa AHN , Fare ATS , Andriamampionona TF , Ranoharison HD , Rakotomalala DP , Ranivontsoarivony M , Rakoto FA , Randrianjafisamindrakotroka NS
Published: April 2024

Thyroid nodules should not be neglected due to the possibility of cancer. Fine Needle Aspiration (FNA), simple and well tolerated procedure, currently allows reaching the majority of diagnoses in pre-operative period. Results on thyroid cancer prevalence in Madagascar seem discor- dant, and cancer was identified only after thyroid surgery. Our objective is to determine the prevalence of thyroid cancer from the cytopatholst ogy examination results. This is a descriptive and cross-sectional study conducted at the University Hospital of Antananarivo from January 1th to April 30 2014, involving patients who underwent fine-needle aspiration under ultrasound guidance of thyroid nodules suspects of cancer. The samples were taken and spread by the same team of operators (ENT head and neck surgeons, endocrinologists). They were then analyzed by a team of cytopathologists. Cystic nodules were excluded from this work. The results of the cytopathology examination were expressed according to the Bethesda classification. In a population of 30 patients included in this study, the mean age was 46.53 years. There was a female predominance (n=26 or 86.67%). The nature of cytological smears was malignant in 13.33% of cases (n=4), benign in 66.67% of cases (n=20), indeterminate in 3.33% of cases (n=1), while the samples were non-contributory in 16.67% of cases (n=5). FNA may change the prevalence of thyroid cancer in Antananarivo.
Paludisme observé chez les patients fébriles au Centre de Santé Materno-Infantile de Moramanga en 2007-2009
Authors: Rakotomalala RS , Randriamihangy N , Ntoe Zara A , Andrianarivelo A , Rakoto Alson O , Rasamindrakotroka A
Published: April 2024

Introduction. In Madagascar, a fever is too often seen as synonymous with malaria. It is difficult to prevent self-medication with anti-malarial. Our objectives were to estimate the prevalence of malaria, to determine the frequency of self-medication with anti-malarial for fever and to identify the main signs of malaria. Methods. We conducted a retrospective study from June 2007 to May 2009 at CSMI in febrile patients. The variables studied were gender, age, residence, clinical signs, result of Rapid Diagnostic Test (RDT) and self-medication for malaria. Results. We enrolled 3710 patients. RDT has confirmed 139 cases of malaria (3.75%) aged 3 months to 59 years (mean = 9.73 years). In 58.27% of cases malarials were female (p>0.05). The age group of 1 to 5 years (47.48%) was the most affected (p>0.05). Plasmodium falci- parum was involved in 99.3% of cases (n=138). Patients in the suburbs represented 54.67% of malarials (p<0.001). The sensitivity and specificity of fever for the diagnosis of malaria were 61% and 50% respectively, and the PPV and NPV of 5% and 97%. Predictive clinical signs identified (p<0.05) were headache (32.37%), vomiting (24.46%) and chills (20.14%). Self-medication with anti-malarial was found in 8.46% (n=314). Conclusion. The prevalence of malaria was low. There are no specific signs of this disease. The most predictive signs of malaria were headache, vomiting and chills. Self-medication with anti-malarial remains a topical issue.
Profil des marqueurs lipidiques dans le diabète de type 2, cas de la ville de Lubumbashi en République Démocratique du Congo
Authors: Tshikongo AK , Kyandabike RK , Amuri SB , Otshudi AL , Kalala ZL
Published: April 2024

Introduction. In type 2 diabetes, there is a particular dyslipidemia is an important risk factor for cardiovascular disease. Quantitatively, the changes in serum lipids, which define the diabetic dyslipidemia is characterized by elevated triglycerides and decreased HDL cholesterol. By cons, serum cholesterol, and especially LDL cholesterol is universally accepted as the major atherogenic lipoprotein is often within the limits of the standard. This work would identify the lipid profile in type 2 diabetic met in the city of Lubumbashi in the Democratic Republic of Congo. Patients and methods. This is a case-control study conducted from June to August 2014 in Lubumbashi (Democratic Republic of Congo). We have included in this prospective study of type 2 diabetic patients recognized and diagnosed (group I) and non-diabetic controls (group II) matched for age and sex. Parallel to classical biological assessment, analyses of cardiovascular risk factors were carried out: HDL Choles- terol, LDL Cholesterol, total cholesterol and triglyceride. The results obtained were compared in the two groups and the level of significance was set at p <0.05. Results. The results show a significant difference between the two groups of LDL, HDL, triglycerides and total cholesterol. Indeed, signifi- cantly elevated total cholesterol, LDL cholesterol and triglycerides, and low HDL- cholesterol were recorded in the plasma of type 2 diabetic patients (group I). This dyslipidemia would be attributed to an increase in circulating free lipids in the plasma due to insulin resistance present in Type 2 diabetes. Conclusion. Type 2 diabetes are at significantly increased risk of cardiovascular disease such as angina, heart attack, stroke or peripheral vascular disease. These complications of diabetes affecting large arteries are particular consequence of dyslipidemia.
La prévention de la transmission mère-enfant du VIH à Antananarivo, Madagascar
Authors: Ravoavison N , Rakotoarivelo RA , Rakotomboahangy TM , Andrianampanalinarivo HR , Randria MJD , Andrianasolo RL
Published: April 2024

Introduction. To assess the safety and efficacy of antiretroviral drugs used in the context of PMTCT in Antananarivo. Patients and methods. A multicentric retrospective and descriptive cross-type study in three reference centers that support pregnant women with HIV in Antananarivo. Were recruited those who were followed between June 2010 and June 2012. Results. Among the 29 pregnant women recruited, eighteen were included in our study. Were excluded pregnant women who have not had PMTCT or have being lost of follow up, newborns undetected. The mean age was 27.72 years (range 19-38 years). Prophylaxis using combi- nation of Zidovudine with Lamivudine and Lopinavir/Ritonavir was administered to all mothers and Zidovudine associated with Nevirapine in all newborns. Headache (11.11%) and anemia (16.67%) were the adverse effects of antiretroviral most encountered. Cesarean section was performed in 83.33% (n=15). Exclusive breast feeding protected with ablactating to six months was performed in 16.67 % of infants (n=3). The rate of Mother to Child Transmission of Human Immunodeficiency Virus was 11.11% (n=2). Conclusion. According to our results, as recommended by the National Program for the Fight against HIV/AIDS for the prevention of mother to child transmission of HIV, molecules are in most cases, well tolerated and provide an acceptable protection of newborns exposed to infec- tion. Nevertheless, much effort must be provided to enhance adherence in therapy and fight against loss of follow up.
Caractéristiques épidémio-cliniques des cancers des voies aéro- digestives supérieures au Service Oncologie du CHUA/JRA de 2008 à 2012
Authors: Randriamanovontsoa NE , Hasiniatsy NRE , Razakanaivo M , Rafaramino F
Published: April 2024

Introduction. Currently, cancers of the upper aerodigestive tract remain a global public health problem. In Madagascar, the cancer registry data is not avalaible making a lack of knowledge on these tumors. This work aimed to describe the epidemiology and clinical profiles of malig- nant tumors of the upper aerodigestive tract in oncology unit of University hospital Joseph Ravoahangy Andrianavalona (HUJRA). Patients and methods. This is a retrospective descriptive study from 1st January 2008 to 31st December 2012 of patients who had head and neck cancer with histological proof. Results. For the 161 cases we collected, mean of age was 53.36 years and the sex ratio at 1.48. Time to consultation was greater than or equal to 12 months in 38.45%. Smoking and alcohol use accounted for 63%. Cancer of the oral cavity held the first rank (42%), followed by the oropharynx (17%). Histologically, squamous cell carcinoma predominated 81.60%. Nearly 64% of patients were diagnosed at stages III and IV. Conclusion. This study differs from the literature by the predominance of the tumor endobuccal. It doesn't reflect the reality of the Malagasy people, so the realization of a national cancer registry would characterize cancers of the upper aerodigestive tract in Madagascar.
Etiologies des infections génitales communautaires au sein du Centre Hospitalier Universitaire Mitsinjo Betanimena, Toliara
Authors: Rakotoniaina AI , Zafindraibe J , Raherinaivo A , Fenomanana S , Razanakolona RM , Rasamindrakotroka A
Published: April 2024

Introduction. The prevalence of genital infections community continues to evolve in time but also in space. Not only is a primer study on some etiologies community genital infections like gonorrhea and trichomoniasis but also to update the data of other studies on the syphilitic infection and chlamydia. Our goal was to determine the prevalence of the etiologies of community genital infections in the Hospital Mitsinjo Betanimena, Toliara II Madagascar and to identify the clinical information provided in these infections. Patients and methods. This is a retrospective descriptive study of 161 samples in the Hospital Mitsinjo Betanimena. Genital specimens for research of Neisseria gonorrhoeae and Trichomonas vaginalis, blood samples for Treponema pallidum and Chlamydia trachomatis. We ana- lyzed all the results of these samples and clinical information mentioned on the exam application form. Results. Of 161 samples, we found that the prevalence of Chlamydia trachomatis, Treponema pallidum, Neisseria gonorrhoeae and Trichomonas vaginalis was 39.28%, 16.66%, 9.09% and 1.81% respectively. Seventy-two percent (72%) of clinical information provided was leucorrhoea. Conclusion. The main etiology of community genital infections found in our study was Chlamydia trachomatis. Leucorrhea is the main clinical manifestation.
Insuffisance rénale obstructive secondaire à une hypertrophie prostatique : cas recensés dans un service de Néphrologie
Authors: Rabemiarason RN , Ramilitiana B , Ranivoharisoa EM , Rasaona VM , Randriamanantsoa LN , Randriamarotia HWF
Published: April 2024

Introduction. Obstructive renal failure secondary to prostatic hypertrophy is one affection that remains topical. We describe the epidemio- clinical, paraclinical, therapeutic and evolutionary aspects of obstructive renal failure due to prostatic hypertrophy in the Nephrology Unit of Befelatanana hospital in Antananarivo, Madagascar. Patients and methods. It is a retrospective, descriptive and analytical study over a period of 6 years from january 2005 to august 2011. Results. Thirty-eight patients were selected. The average age was 68.63 years old. Fifty seven point eighty nine percent had acute renal failure and 42.11% with chronic renal failure. The majority of our patients have a moderate renal insufficiency (47.37%). Forty four point seventy four percent was transferred in urology. Conclusion. Obstructive renal failure secondary to an prostatic hyperthrophy is common for all men over age 50. Digital rectal examination is a useful tool.
Profil et issue des femmes présentant une grossesse extra-utérine au Centre Hospitalier Universitaire de Fianarantsoa
Authors: Andriamifidison NZR , Rafamatanantsoa JF , Randriatsarafara FM , Rakotomahenina H , Tovoniaina JD , Randriambelomanana JA , Randrianarimanana VD , Rakotomanga JDM
Published: April 2024

Introduction. Ectopic pregnancy represents the main cause of morbidity and mortality in women of childbearing age. This study aims to de- termine the epidemiological and clinicalaspect of ectopic pregnancy and to evaluate its management and treatment. Patients and methods. A cross sectional study about women presenting ectopic pregnancy was conducted at the Academic Hospital of Fi- anarantsoa from January, 1st to June 30th, 2014. Results. We investigated 43 (1.67%) patients with ectopic pregnancy. The mean age ±SD was 30.3±5.6 years. The proportion of women at their first or second gravidity was 58.14%. Among those women, 44.18 %were uni or biparous. The levels of instruction of the women was low, 48.88% of them were at primary level. More than a half (53.48%) of the patients lives in an urban area. The proportion of women getting sexually transmitted infections and carrying out abortion is respectively estimated to 58.14% and 27,91 %. The main clinical symptoms is represented by the association of amenorrhea, abdominal and pelvic pain, metrorrhagia (71.2%). The diagnosis was established by pelvic ultrasonography and Beta HCG assay. Ampullar pregnancy represented the most frequent clinical forms and it was unruptured in 60.9% of the case. Salpingectomy represented the most practiced surgical intervention (85.4 %). No death were recorded. Conclusion. The improvement of ectopic management requires an early diagnosis. Surgical intervention represents the one treatment of its complication.
Difficultés diagnostiques de l’association Amoebome colique et abcès amibien du foie : à propos d’une observation à Dakar
Authors: Touré PS , Léye A , Léye YM , Diop MM , El Fajri S , Diop M , Ka MM
Published: April 2024

Amoebiasis is the most common gastrointestinal parasitosis infection in developing countries. It offers a clinical polymorphism without any particular specificity. It can often be complicated by amoeboma, which is an inflammatory pseudotumor of the colon. The discovery of a concomitant amoeboma with an amoebic liver abscess, often leads to colonic neoplasia suspicion with hepatic secondary location. We report a case of this combination in a 39-year-old Senegalese man. In our case the radiological and endoscopic results made us think first to a colon cancer. The detection of pus in an ultrasound guided tap of the liver associated with positive amoebic serology, in the absence of histological characteristics of malignancy in colonic biopsies, allowed to retain the diagnosis of amoeboma. The favorable clinical and radiological progression were attributed to treatment with metronidazole. The amoeboma although rare, should be considered in the tropics as a differential diagnosis of colon cancer in all presentations of colonic masses, even more so if an infectious syndrome was found. This can prevent the patient risky surgical procedures.
Polyarthralgie aigue fébrile avec endocardite chez un grand enfant : maladie de Still ou rhumatisme articulaire aigu ?
Authors: Rakotonirainy OH , Rakotoharivelo H , Ralandison S
Published: April 2024

Diagnosis of acute rheumatic fever and the Still's disease with endocarditis is misleading. Since 3 months, RJ, 15, had a febrile polyarthritis of large joints, non-migratory, accompanied by a mitral systolic murmur. Laboratory tests showed important inflammatory syndrom , high streptococcal antibody titre (650 UI/mL), absence of antinuclear antibody and rheumatoid factor. Hemocultures were negatives. PR interval was prolonged (0,24 s) on electrocardiogram. Echocardiography showed mitral valve da- mage. First the patient received Penicillin G and prednisone (1 mg/kg/d) with no improvement after 4 weeks. Secondarily, with indometacin (NSAID) 75 mg per a day: clinical, biological and ultrasound symptoms improved after 5 days. Our patient fulfilled both diagnostic criteria for Still's disease as that of acute rheumatic fever. The clinical features and improvement with Indometacin were more in favor of Still’s disease. Making the difference between those two diseases is important because treatment and progno- sis are very different.
Hypertension artérielle et arrêts de grossesse : penser au phéochromocytome
Authors: Raherison RE , Rakotomalala PAD , Rambel HA , Rantomalala YH , Ramahandridona G
Published: April 2024

Pheochromocytoma is a rare tumor responsible of secondary hypertension. This tumor can be discovered during pregnancy. It can be re- sponsible of significant maternal and fetal morbidity and mortality.Our aim was to describe the clinical features and the outcome of pheochro- mocytoma during pregnancy. A 26-year-old woman developed unexplored hypertension during two previous pregnancies. These episodes of hypertension occurred before the twentieth week of gestation excluding. Her medical history was unremarkable. After the second abortion were undertaken explorations referred to etiological including abdominal ultrasound, abdominal CT scan and measurement of urinary catecholamine metabolites. These investigations allowed the diagnosis of pheochromocytoma. A partial right adrenalectomy carrying the tumor was performed and confirmed the diagnosis of benign pheochromocytoma. Her blood pressure normalized without any immediate complication. Pheochromocytoma during pregnancy may induce diagnostic and prognostic issues. Therefore, any hypertension in pregnancy patient should be explored to screen a possible pheochromocytoma.
Neuropathie optique toxique bilatérale à l’éthambutol: à propos de deux cas
Authors: Volamarina RF , Rajaona RA , Raobela A , Rakotoarisoa R , Randrianarisoa H , Raharivelo A , Razafindrabe JB , Bernardin P
Published: April 2024

Tuberculosis is a public health problem in Madagascar. Among the anti-tuberculosisdrugs, ethambutol causes severe toxicity to the optic nerve. We reported two cases of toxic optic neuropathy induced by ethambutol. Neuropathy is dose dependent, after a variable latency, and occured with bilateral visual impairment, a change of color vision, and central scotoma. The mechanism is not well understood although several hypotheses have been evoked. We suggest information to patients and promote multidisciplinary care.
Polyorchidie : à propos d'une nouvelle observation au Sénégal
Authors: Sarr A , Fall B , Sow Y , Thiam A , Ondo CZ , Sine B , Diao B , Fall PA , Ndoye AK , Ba M , Diagne BA
Published: April 2024

The polyorchidism is a rare malformation with a hundred cases reported in the literature. We describe a new case in Senegal, an adult of 25 years who presented with left cryptorchidism. The option of conservative surgery was taken. Through this case and literature review, we will discuss the epidemiological, clinicopathological and therapeutic apects of this disease.
La nutrition parentérale chez le patient adulte critique
Authors: Rakotondrainibe A , Randriamizao HMR , Rajaonera AT , Rakotomavo FA , Razafimahefa SH , Raveloson NE
Published: April 2024

Critically ill patient often presents nutritional disorders, from his admission or during hospital stay. Nutritional support is an essential part of the treatment. The main aim of this nutritional care is to optimize nutritional state of the patient by adequate calories intake and to cover deficits. Parenteral nutrition will be instaured in case of any intolerance or contraindication of oral or enteral nutrition. This therapeutic has no negligent advantages, but can engender severe complications which can compromise vital prognosis. So, to have an adequate nutritional support by parenteral rout, clinical and biological monitoring are essential.
PENGEMBANGAN MODUL TEMATIK BERBASIS INKUIRI PADA TEMA 2 SELALU BERHEMAT ENERGI SUBTEMA 2 MANFAAT ENERGI KELAS IV SD/MI
Authors: Astuti Nindi Widi , Astuti Mardiah , Sofyan Fuaddilah Ali
Published: April 2024

Pendidikan merupakan kebutuhan yang sangat penting dalam meningkatkan kualitas sumber daya manusia. Melalui pendidikan manusia dapat menemukan hal-hal baru yang dapat dikembangkan dan diperoleh untuk menghadapi tantangan yang ada sesuai dengan perkembangan zaman. Sistem pendidikan  nasional senantiasa harus dikembangkan sesuai dengan  kebutuhan dan perkembangan yang terjadi baik di tingkat lokal, nasional, maupun global. Berdasarkan uraian latar belakang diatas, penulis akan melakukan penelitian dengan Judul “Pengembangan Modul Tematik Berbasis Inquiri Pada Tema 2 Selalu Berhemat Energi Subtema 2 Manfaat Energi Kelas IV SD/MI”. Tujuan dari penelitian ini adalah untuk menguji dan menghasilkan bahan ajar modul yang valid, praktis dan efektif. Penelitian ini menggunakan jenis penelitian Pengembangan atau Research and Develoment yaitu metode penelitian yang digunakan untuk menghasilkan produk dengan model pengembangan yang mengikuti alur desain formatif evaluation (Tessmer). Uji coba terbatas pada penelitian ini dilaksanakan pada 19 peserta didik kelas IV A SD Negeri 32 Rantau Bayur. Teknik pengumpulan data yang digunakan dalam penelitian ini yaitu uji validasi pada beberapa ahli dan angket responden peserta didik. Hasil penelitian menunjukan Rekapiitulasi Validator (1) Ahli desain 77% dengan kategori valid; (2) Ahli Bahasa 98% dengan kategori sangat valid; (3) Ahli materi 83% dengan kategori sangat valid; dan Rekapitulasi Kepraktisan (1) One to One 83% dengan kategori sangat praktis; (2) Small Group 82% dengan kategori sangat praktis; serta Rekapitulasi Keefektifan pada hasil post tes memperoleh angka 87% dengan kategori sangat efektif.
PARENTING KESEHATAN DIRI DAN LINGKUNGAN: PENTINGNYA GIZI BAGI PERKEMBANGAN ANAK
Authors: Wulandari Yuwinda , Apriyanti Liana , Meiyansari Monika , Nurhasanah Nurhasanah , Putri Yecha Febrieantha
Published: April 2024

Penelitian ini berjudul Pentingnya kesehatan diri dan lingkungan : Pentingnya gizi bagi perkembangan anak. Di dalam artikel ini membahas mengenai kesehatan diri dan lingkungan serta pentingnya gizi bagi perkembangan anak. Tujuan dari artikel ini adalah untuk mengetahui apa itu kesehatan diri dan lingkungan serta apa pentingnya gizi bagi perkembangan anak.Kesehatan sendiri dapat diartikan sebagai kondisi kesejahteraan fisik, mental, dan sosial yang lengkap dan bukan sekadar tidak adanya penyakit atau kelemahan. Lingkungan sendiri dapat diartikan sebagai ruang dimana manusia bergerak dalam rangka melakukan aktifitas sosialnya yang melibatkan semua aspek dalam ruangan tersebut sesuai dengan insting-insting kebutuhan manusia yang menggerakkan daya aktifitas sosial manusia yang berkaitan. Gizi merupakan salah satu faktor yang mutlak diperlukan dalam proses tumbuh kembang fisik, sistem saraf dan otak, serta tingkat intelektualitas dan kecerdasan manusia. Pemenuhan kebutuhan gizi (nutrien) merupakan faktor utama untuk mencapai hasil tumbuh kembang agar sesuai dengan potensial genetic.
GANGGUAN GEJALA DISLEKSIA PADA ANAK USIA DINI
Authors: Oktamarina Lidia , Rosalina Evita , Utami Lucia Septiana , Duati Syah Fitri Kurnia , Dzakiyyah Cyndi , Sari Riska Puspa , Julita Monika Sales
Published: April 2024

Penderita disleksia akan kesulitan dalam mengidentifikasi kata-kata yang diucapkan dan mengubahnya menjadi huruf atau kalimat. Disleksia tergolong sebagai gangguan saraf pada bagian otak yang memproses bahasa. Disleksia dapat menimbulkan gejala yang bervariasi, tergantung pada usia dan tingkat keparahannya.Pada balita, gejala dapat sulit dikenali, tetapi setelah anak mencapai usia sekolah, gejalanya akan mulai terlihat, terutama saat anak belajar membaca. Deteksi dan penanganan sejak usia dini terbukti efektif meningkatkan kemampuan penderita dalam membaca.
PROPHETIC PARENTING : KONSEP IDEAL POLA ASUH ISLAMI
Authors: Julita Monika Sales , Utari Nifty , Handayani Rahmah , Yanti Vira Dwi Putri , Putri Yecha Febrieanitha
Published: April 2024

Keberadaan anak dalam suatu keluarga menjadikan keluarga itu terasa hidup, harmonis, dan menyenangkan, sebaliknya ketiadaan anak dalam keluarga menjadikan keluarga tidak berarti apa-apa, karena kehilangan salah satu ruh yang dapat menggerakkan keluarga itu. Di mata seorang bapak, anak akan menjadi penolong, penunjang, pemberi semangat, dan penambah kekuatan. Di mata seorang ibu, anak menjadi harapan hidup, penyejuk jiwa, penghibur hati, kebahagiaan hidup, dan tumpuan di masa depan. Dalam pola asuh orangtua terjadi interaksi dengan anak yang disebut dengan pola asuh. Pola asuh disebut dengan Parenting control  yang bertujuan untuk mendidik anak untuk menyesuaikan diri terhadap harapan sosial yang layak dan dapat diterima. Hakekat mengasuh anak adalah sebuah usaha yang nyata dari orang tua dalam bentuk mensyukuri nikmat dan karunia Allah SWT dan dalam mengemban amanah yang diberikan oleh-Nya sehingga anak menjadi sumber kebahagiaan, penerus keturunan dan menjadi manusia yang mandiri. Dari materi di atas dapat disimpulkan bahwa pola asuh adalah sikap yang dilakukan orangtua dalam berinteraksi dengan anak dengan melihat cara orangtua memberikan kedisiplinan, hadiah, hukuman, perhatian dan tanggapan sehingga mempengaruhi pembentukan kepribadian anak, karena orangtua sebagai model awal bagi anak dalam berhubungan dengan orang lain.
DETERMINAN PENGARUH PENGAMBILAN KEPUTUSAN PEMBELIAN PERUMAHAN NON MBR DI KABUPATEN SLEMAN
Authors: Khoirudin Rifki , Khasanah Uswatun , Zakiyyah Nurul Azizah Az
Published: April 2024

Rumah menjadi salah satu kebutuhan pokok selain pangan dan papan.Tingginya kebutuhan atas rumah di Kabupaten Sleman menjadi peluang bagi pengembang perumahan terutama perumahan Non-MBR. Tujuan penelitian ini adalah untuk menganalisis determinan pengambilan keputusan pembelian perumahan Non-MBR di Kabupaten Sleman. Metode penelitian yang digunakan adalah multiple linear regression analysis. metode statistika serta ekonometrika. Alat bantu analisis yang digunakan adalah SPSS 25.0. Data penelitian yang digunakan adalah data primer dengan jenis data cross section. Sampel diperoleh dari 14 perumahan yang terletak di Kabupaten Sleman. Jumlah responden dalam penelitian ini adalah 82 responden yang diambil dari 14 perumahan di Kabupaten Sleman dengan metode penentuan jumlah sampel berdasarkan rumus slovin. Metode pengambilan sampel menggunakan random sampling. Hasil penelitian menyimpulkan bahwa secara simultan seluruh variabel independen berpengaruh terhadap pengambilan keputusan pembelian perumahan Non-MBR. Secara parsial, variabel kesesuaian tingkat harga, lokasi, fasilitas dan kualitas produk berpengaruh positif dan signifikan terhadap pengambilan keputusan pembelian perumahan Non-MBR.
GANGGUAN PERKEMBANGAN SOSIAL AGAMA DAN MORAL DILIHAT DARI PANDANGAN: PSIKOANALISA, PSIKOLOGI SOSIAL, PSIKOLOGI ISLAM (GANGGUAN BIPOLAR)
Authors: Lasmini Lasmini , Pingky Lisa , Raudho Evi Sri , Oktamarina Lidia
Published: April 2024

Penelitian ini membahas tentang gangguan perkembangan sosial agama dan moral pada anak usia dini dari pandangan : 1. Psikoanalisa, 2. Psikologi Sosial, 3. Psikologi islam. Penelitian ini bersifat Kualitatif Deskriptif. Manusia adalah makhluk ciptaanAllah yang paling sempurna di antara seluruh makhluk di muka bumi ini. Manusia memiliki banyak masalah yang dihadapi dibandingkan makhluk lain dalam menjalain kehidupan, baik dari kontak sosial dan lain sebagainya. Psikologi memiliki berbagai macam ilmu, salah satu diantaranya adalah psikologi yang membahas tentang perkembangan kejiwaan manusia dari prenatal sampai hampir meninggal. Pada kesematan ini akan mengkaji dan memahami salah satu aliran psikologi yaitu aliran psikoanalisa. Selain dikaji ruang lingkup psikoanalisa serta kaitannya dengan psikologi islam pada gangguan perkembangan sosial agama dan moral pada anak usia dini.Gangguan bipolar merupakan gangguan kronis berulang ditandai dengan munculnya fluktuasi keadaan mood dan energi. Gangguan ini dialami lebih dari 1% populasi dunia terlepas dari kebangsaan, asal etnis, atau status sosial ekonomi. Gangguan bipolar ialah gangguan yang lebih jarang dibandingkan dengan gangguan sepresif berat. Prevelanesi antara laki-laki dan perempuan sama besar. Onset gangguan bipolar adalah dari masa anak-anak (usia 5-6 tahun) - 50 tahun atau lebih rata-rata usia yang terkenal adalah usia 30tahun.Penyebab terjadinya gangguan bipolar dipengaruhi oleh beberapa faktor seperti studi genetik, disregulasi neurotransmitter, struktur anatomis otak, regulasi neuroendoktrin, dan faktor psikososial. Risiko anak-anak dengan orang tua yang mengalami gangguan bipolar adalah empat kali lebih besar dibandingkan dengan risiko anak dengan orang tua sehat.Penanganan saat ini untuk pasien gangguan bipolar berfokus pada pemberian terapi non-farmakologi dan farmakologi untuk gangguan bipolar meliputi: terapi interpersonal, terapi perilaku, terapi kognitif, dan terapi lainnya.
PENGELOLAAN HUBUNGAN SEKOLAH DAN MASYARAKAT DICIPTA KREATIF BANGSA (CKB) PLAYGROUP
Authors: Rahmah Annisa Ajeng Tri , Salsabila Salsabila , Rahayu Desti Sri , Wulandari Retno
Published: April 2024

Penelitian ini bertujuan untuk mengetahui bagaimana hubungan sekolah Cipta kreatif bangsa dengan masyarakat di sekitar sekolah penelitian ini membahas tentang bagaimana hubungan pihak sekolah dengan orang tua anak dan bagaimana optimalisasi pemanfaatan lingkungan sekolah serta mengetahui bagaimana strategi sekolah dalam mengenalkan sekolah pada masyarakat luar. Dengan melihat dan mengetahui bagaimana hubungan sekolah dengan masyarakat penelitian ini tentu dilakukan untuk membuktikan bahwa pengelolaan hubungan sekolah dengan masyarakat sangat penting untuk mewujudkan tujuan pendidikan yang yang baik bagi suatu lembaga agar tercapai dengan baik pula Tujuan dari sekolah tersebut dan dengan adanya pengelolaan hubungan sekolah dan lingkungan masyarakat yang baik maka proses pembelajaran dan hal lainnya yang berkaitan dengan pendidikan atau proses belajar mengajar di sekolah juga akan berjalan dengan baik dan lancar tanpa adanya hambatan.
ANALISIS PARTISIPASI MASYARAKAT DALAM PENGELOLAAN PAUD NONFORMAL KELOMPOK BERMAIN DI DAERAHNYA
Authors: Anisa Feny , Septianingrum Dila , Triwinanti Arum , Wulandari Retno
Published: April 2024

Penelitian ini bertujuan untuk memahami secara komprehensif tentang analisis partisipasi masyrakat dalam pengelolaan PAUD nonformal kelompok bermain di daerahnya. Kelompok bermain dapat mengembangkan pribadi seorang anak secara positif dan terarah karena dalam setiap kelompok bermain menggunakan metode bermain dalam setiap pendekatannya dengan anak didik. Bermain dipandang sebagai suatu cara dari pendidikan dan anak dapat meniru kehidupan orang dewasa dengan baik. Melalui kegiatan bermain anak akan mengembangkan kemampuan dalam menyelesaikan masalah, belajar menampilkan emosi yang diterimanya dan juga belajar bersosialisai agar kelak terampil dan berhasil menyesuaikan diri dari kelompok teman. Anak adalah individu yang unik, dengan keunikannya anak berhak mendapat layanan pendidikan yang sesuai kebutuhannya. Anak membutuhkan perawatan, pengasuhan, dan pendidikan yang layak di rumah, sekolah, dan masyarakat. Anak membuthkan perawatan, pengasuhan, dan pendidikan yang layak di rumah, sekolah, dan masyarakat. Anak memerlukan perhatian yang intensif dari orang dewasa untuk mengembangkan dirinya. Salah satu upaya meningkatkan pertumbuhan dan perkembangan anak secara optimal adalah pedoman penyelenggaraan PAUD. Pedoman tersebut berupa acuan untuk memudahkan pelaksaan kegiatan agar berlangsung dengan baik dan lancar sesuai dengan kebutuhan perkembangan anak. Partisipasi masyarakat dalam PAUD sangat penting. Karena partisipasi masyarakat dapat mensukseskan PAUD. Terutama keluarga atau orang tua karena merupakan penanggung jawab utama dalam optimalisasi tumbuh kembang anak. Penelitian ini merupakan penelitian yang menggunakan metode deskriptif kualitatif dengan pengumpulan data berupa jurnal-jurnal terlebih dahulu. Teknik yang digunakan dalam penelitian ini yaitu analisis isi. Hasil penelitian yang ingin dicapai berupa analisis partisipasi masyarakat dalam pengelolaan PAUD nonformal kelompok bermain di daerahnya yang dapat dijadikan pedoman bagi seluruh individu atau lembaga yang membutuhkannya.
MENYUSUN STRATEGI PEMASARAN KELOMPOK BERMAIN DI ERA NEW NORMAL
Authors: Anggraini Ade Merly , Novitasari Dini , Oktaria Sri Wahyuni , Wulandari Retno
Published: April 2024

Tulisan ini membahas tentang menyusun strategi pemasaran kelompok bermain di era normal. Oleh karena itu pertumbuhan lembaga Kelompok Bermain(KB) dan animo masyarakat yang tinggi masih kurang diikuti oleh manajemen pemasaran yang dilakukan secara profesional. Kegiatan pemasaran tidak hanya harus dilakukan oleh lembaga pendidikan yang baru berdiri, tetapi juga lembaga pendidikan yang sudah lama berdiri atau lembaga pendidikan yang sudah dianggap terkenal sekalipun. Pemasaran juga dapat dijadikan sebagai mekanisme penjelasan dan rasionalisasi suatu penawaran program dengan berbagai keunggulannya. Pemasaran pendidikan merupakan proses perencanaan, pengorganisasian, pengarahan, dan pengawasan pendayagunaan sumber daya yang dilakukan secara efisien dan efektif guna menawarkan jasa pendidikan. Kelompok bermain adalah salah satu bentuk satuan PAUD yang menyelenggarakan program pendidikan dan pengasuhan bagi anak usia 3-4 tahun. Era New Normal adalah perubahan perilaku untuk tetap melakukan aktivitas normal dengan ditambahkan penerapan protokol kesehatan disetiap kegiatan seseorang baik didalam ruangan maupun diluar ruangan guna mencegah terjadinya penulatan virus covid-19. sebabnya Setiap lembaga pendidikan anak usia dini berlomba-lomba menawarkan keunggulannya untuk menarik minat masyarakat. Dibutuhkan koordinasi yang baik antara guru dengan kepala sekolah dalam menciptakan inovasi memasarkan jasa pendidikan. Data dalam artikel ini diperoleh dari buku artikel dan  internet yang berhubungan dengan menyusun strategi pemasaran kelompok bermain di era new normal ini, kemudian data-data ini diolah dengan bahasa sendiri sehingga mendapatkan data-data yang sesuai dengan apa yang sedang dibahas. Hasil dari artikel ini menunjukkan bahwa ada beberapa poin yang berkaitan dengan pemasaran kelompok bermain di era new normal. Artikel ini diharapkan dapat menjadi bahan kajian untuk pembahasan pembahasan selanjutnya mengenai pemasaran kelompok bermain di era new normal.
EFEKTIVITAS MANAJEMEN KELAS KELOMPOK BERMAIN DI KB NUSANTARA INDAH
Authors: Rahmini Latifa , Pratama Yuda , Wulandari Retno
Published: April 2024

Efektivitas manajemen kelas kelompok bermain pada KB Nusantara Indah dimaksudkan untuk menciptakan proses pembelajaran efektif. Hal tersebut dilakukan dengan 1).Menciptakan lingkungan belajar yang kondusif, 2).Melakukan pengaturan sedemikian rupa pada waktu untuk melakukan aktivitas bagi anak ini dilakukan dengan pertimbangan fleksibelitas dan mengacu pada karakteristik anak, 3). Mengatur Ruang Kelas, dengan cara mengatur ruang kelas, posisi duduk, pengaturan perabot dan alat permainan, serta membagi ruangan. Adapun faktor yang mempengaruhi efektivitas manajemen kelas kelompok bermain pada KB Nusantara Indah adalah 1). Lingkungan fisik yang tidak mendukung, Seperti: kondisi kelas yang gaduh karena aktivitas anak seperti megobrol, berselisih, berteriak dan lain sebagainya sehingga mengganggu aktivitas belajar dikelas, b). Terdapat anak tidak bisa tenang seperti berlari-lari di dalam kelas, dan anak-anak lainnya tampak berkeluyuran tanpa tujuan, c). Ruangan kelas yang kacau balau akibat aktivitas anak, d). Penempatan perabot yang tidak mempertimbangkan penggunaan oleh anak sehingga mengganggu aktivitas anak lainnya, 2) Lingkungan fisik yang mendukung seperti: Hasil pekerjaan anak-anak dipajangkan, tumbuhan hijau yang sehat di seluruh ruangan, poster berwarna-warni di dinding, dan gorden baru di jendela, ruangan diatur dalam area aktivitas yang berbeda, terdengar senandung berbicara dan tertawa, tetapi tidak ada teriakan, anak- anak sedang mengerjakan beberapa aktivitas yang diatur oleh para guru, material disimpan di atas rak terbuka yang rendah, dan anak-anak dapat menjangkaunya dengan mudah, fasilitas dan peralatan ditempatkan berdekatan dengan aktivitas yang akan dilakukan anak.
PENGELOLAAN PENDIDIKAN DAN TENAGA KEPENDIDIKAN
Authors: Zahidah Ummi , Afifa Fika Rizki , Apriyanti Liana , Wulandari Retno
Published: April 2024

Pendidikan adalah sebagai usaha sadar dan terencana untuk mewujudkan suasana belajar dan proses pembelajaran untuk peserta didik secara aktif mengembangkan potensi dirinya untuk memiliki kekuatan spiritual keagamaan, pengendalian diri, kepribadian, kecerdasan, akhlak mulia, serta keterampilan anak. Dalam penelitian ini dibahas mengenai pengelolaan pendidikan dan tenaga kependidikan kelompok bermain di KB MELATI Kec. Kelekar Kab. Muara enim, yang mencakup manajemen pendidikan, konsep manajemen, prinsip-prinsip manajemen fungsi manajemen, tugas, fungsi dan tujuan pendidik dan tenaga kependidikan. Penelitian ini dilakukan untuk melihat pentingnya pengelolaan pendidikan dalam lembaga kelompok bermain di KB MELATI. Tenaga kependidikan yaitu anggota masyarakat yang mampu mengabdikan diri dalam menyelenggarakan pendidikan. Tenaga kependidikan yang dimaksud adalah pegawai professional yang bekerja dilingkungan  pendidikan atau sekolah, yaitu kepala satuan pendidikan, pendidik, dan tenaga kependidikan yang lainnya. Pendidik dan tenaga kependidikan mempunyai peran, fungsi, dan kedudukan yang sangat strategis. Tenaga kependidikan bertugas melaksanakan administrasi, pengelolaan, pengembangan, pengawasan, dan pelayanan tekhnis untuk menunjang proses pendidikan pada lembaga kelompok bermain. Tenaga kependidikan memiliki lingkup “profesi” yang lebih luas, yang juga mencakup yang di dalamnya pendidik, pustakawan, staf administrasi, staf pusat sumber balajar Tenaga kependidikan terdiri atas penilik, kepala sekolah, penyelenggara pengelola, petugas administrasi, dan petugas kebersihan.