bluuebunny/crossref_metadata_2025 huggingface dataset:
Treatment Outcome of Displaced Proximal Humeral Fractures with Joshi’s External Stabilization System: A Prospective Study
Authors: Karki Prateek , Ranabhat Roshani , Shrestha Dinesh Kumar , KC Dipendra , Sapkota Suhail
Published: September 2022

Introduction: Proximal humeral fracture accounts for four to five percentage of all fractures. Undisplaced fractures can be managed conservatively however, for displaced fractures; no particular method is a panacea. In our study we treated displaced proximal humeral fracture with Joshi’s external stabilizing system.

Aims: To evaluate functional outcome of displaced proximal humerus fractures managed byJoshi’s external stabilizing system.

Methods: This prospective study includedall patients with displaced proximal humerus fracture (Neer’s type two and three); treated with JESS from August 2018 to August 2021at Nepalgunj Medical College, Kohalupurand functional outcome was evaluated using Neer’s criteria at final follow-up. Ethical clearance was obtained from Institutional Review Committee.

Results: A total of 40 patients, 23 males and 17 females with mean age of 41.2 years (range from 18 to 60) were included. Mean follow-up duration was 24 ± 1.7 weeks.  All fractures united at an average of 13 ± 1.7 weeks. Twenty-nine patients (72.5%) had an excellent result with average score of 92.7 ± 2.3 and remaining 11(27.5%) had satisfactory functional outcome with average score of 84.7 ± 1.7 according to Neer’s criteria. Three patients had bicipital tendonitis that resolved within eight weeks of implant removal while two had pin tract infection which resolved with oral antibiotics and dressing.

Conclusion: Joshi’s external stabilizing system is an effective treatment option in patients with displaced proximal humeral fractures.
C-Reactive Protein as a Prognostic Marker in Hospitalized Patients with COVID-19
Authors: Shrestha Anil , Shah Gaurav Jung , Neupane Sagar , Shrestha Richa
Published: September 2022

Introduction: COVID-19 is a new infectious disease for which there is currently no treatment and has become a new threat for the populations. Therefore, it is necessary to explore biomarkers to determine disease severity which may help to identify patient at risk of prolonged intensive care or death.

Aims: To evaluate the ability of C-reactive protein to predict the severity of COVID-19 infection.

Methods: This study was conducted on 83 patients with COVID-19 admitted at COVID Unit of Nepalgunj Medical College Teaching Hospital, Kohalpur from April 2021 to June 2021. COVID-19 infection was diagnosed by Reverse Transcription Polymerase Chain Reaction of nasopharyngeal or throat Swab. The study population was divided into mild, moderate and severe cases. The data on demographic characteristics, clinical features and laboratory findings were collected  and analyzed using SPSS version 26. P value less than 0.05 was taken as significant.

Results: The mean levels of C-reactive protein in mild, moderate and severe cases were 2.75 mg/L, 9.87 mg/L and 84.48 mg/L respectively (P value = 0.003). This shows that CRP levels were significantly higher in severe cases and could be used as important biomarker to predict the severity of disease in COVID-19.

Conclusion: The serum level of C-reactive protein can predict the severity and progression of disease in patient with COVID-19. Thus, C-reactive protein should be used as a prognostic marker in COVID-19.
Levonorgestrel Intrauterine System (MIRENA): Initial Experience in the Management of Abnormal Uterine Bleeding
Authors: BC Durga
Published: September 2022

Introduction: The Levonorgestrel intrauterine system (MIRENA) is a long acting contraceptive device act by releasing progesterone into the uterus It is also efficient in medical management of abnormal uterine bleeding. Levonorgestrel intrauterine system is best option for those ladies who want to avoid surgery in cases of abnormal uterine bleeding.

Aims: To assess the effectiveness of MIRENA in abnormal uterine bleeding.

Methods: This is a hospital based cross sectional study done at the department of obstetrics and gynecology in ladies with history of abnormal uterine bleeding. The study was done from January 2020 to January 2022 for a period of two years. Data were collected, recorded in standard Proforma and analyzed by using EESPPS version 17.

Results: Majority of patients were multipara of age group 35-40 yrs. Mirena caused decrease in heavy menstrual blood loss by 2.4% in 4month of use and 47.6% by one year. After one year of use 83.3% patient had better compliance, 9.5% had expulsion, and only 7.1% had to undergo hysterectomy.

Conclusion: Mirena is the best alternative in the medical management of abnormal uterine bleeding with good patient compliance reducing the rate of hysterectomy.
PEMANFAATAN SERABUT KELAPA SEBAGAI BIOSORBEN DALAM REMOVAL COD PADA LIMBAH CAIR INDUSTRI PEWARNA MAKANAN
Authors: Purwaningsih Dian Yanuarita , Muliawati Eka Cahya
Published: September 2022

The liquid waste of the food industry has recently increased. Therefore, when it is discharged into the waters, it will cause turbidity and can damage the ecosystem inside. One of the wastewater treatment techniques is absorption using biosorbents, one of which is made from coconut fiber to reduce the color intensity of the liquid waste. The purpose of this study was to determine the effects of the coconut fiber biosorbent on the color intensity, COD, and pH of the liquid waste of the food industry. In this research, the coconut fiber was delignified with a 2 M NaOH solution and then activated with a 3 N solution. The research variables consisted of the weight percentages of biosorbent by 1%, 2%, 3%, 4%, and 5%, and the contact time of 30 and 60 minutes with shaker stirring. Meanwhile, the most optimum results in COD removal happened at the addition of 4% for 60 minutes, from the initial COD of 1179 mg/L O2 to 780 mg/L O2 within the removal of 26.5%. The highest pH removal of 6.98 occurred in the variable addition of 1% for 30 minutes, whereas the lowest pH removal of 6.5
Implementasi Kanban untuk Meminimalisir Kesalahan Penempatan pada Inventory System
Authors: Kurniawan Wingky , Raharto Raharto , Muryanto Muryanto
Published: September 2022

Saat ini PT. TMMI adalah salah satu perusahaan yang menghasilkan beberapa jenis produk, seperti air, oil dan fuel filter untuk berbagai kendaraan otomotif di Indonesia. Produk yang dilakukan produksi tersebut terdapat dua bagian, yaitu spin on dan element. Keduanya dibedakan dari, spin on menggunakan body, sedangkan element tidak menggunakan body. Pada persediaan PT. TMMI adalah hal yang menjadi prioritas guna berjalan lancarnya proses produksi dan memenuhi kebutuhan konsumen. Maka pada persediaan PT. TMMI terbagi menjadi dua bagian, yaitu bagian bahan baku utama dan bahan baku pendukung. Dikarenakan selama ini telah mengimplementasikan kanban guna melakukan pengendalian dalam jumlah persediaan yang diperlukan. Maka kanban juga digunakan guna mengetahui berapa banyak jumlah persediaan yang digunakan oleh departemen/divisi terkait. Namun pada realitanya kanban yang sudah ada masih belum berjalan sebagaimana mestinya yang didasarkan dari analisis 5M. Maka yang menjadi akar permasalahan pada kanban berada pada bagian man dan method, yaitu pengguna kanban yang tidak menjalankan kanban serta tidak adanya work instruction mengenai kanban itu sendiri. Akar permasalahan tersebut dapat menimbulkan berlangsungya barang parkir, yaitu bang yang tidak dapat menjadi finished goods. Hal ini dikarenakan terjadi kekurangan pada bahan baku penunjang. Barang parkir yang berlansung sebelum perbaikan dari kanban, yaitu sebanyak 30.577 (selama penelitian ini berlangsung di PT. TMMI). Oleh sebab itu, tujuan dalam penelitian ini untuk memperbaiki, mengimplementasikan kembali dan mengendalikan sistem kanban pada persediaan PT. TMMI. Sehingga dari hal ini dapat meminimalisir berlangsungnya barang parkir.
STUDI PENGARUH MEDIA TERHADAP PREFERENSI METODE BELANJA : Studi Kasus Pada Mahasiswa Di Kota Batam
Authors: Xie Lenda
Published: September 2022

Belanja online semakin marak di era modern pada kalangan mahasiswa, terutama setelah Pandemi COVID-19. Mereka dianggap lebih menarik, efektif, dan efisien. Namun, beberapa mahasiswa juga menganggap belanja offline sebagai pilihan yang lebih aman dan tepercaya dari keduanya. Motif Konsumen merupakan informasi penting untuk dipertimbangkan karena sangat menentukan keputusan dan sikap pembelian. Oleh karena itu, penelitian ini bertujuan untuk menunjukkan dan mengkaji preferensi dan motif berbelanja mahasiswa Batam. Kuesioner tentang informasi siswa, preferensi belanja, sikap belanja, dan motif belanja dibagikan dan dikumpulkan untuk penelitian kami. Hasil penelitian melalui SPSS 15.0 Program menunjukkan bahwa motif kegunaan dan motif hedonis mempengaruhi sikap mereka terhadap belanja online secara signifikan dibandingkan dengan motif kesederhanaan, dengan motif kegunaan menjadi motif yang paling dominan. Temuan ini telah berkontribusi pada praktik pemasaran dan studi lebih lanjut tentang perilaku konsumen dalam E-commerce dan dunia digital.
Russia invaded by Germans. Notes of an old soldier who is neither a Peer of France, nor a diplomat, nor a deputy
Authors: Abdullaev E. V.
Published: September 2022

The ending. Continued from Voprosy Literatury (2022, 2).

The publication features a commented translation (the ending) of the brochure La Russie Envahie par les Allemands, authored by Filipp Vigel (Weigel), a former member of the Arzamas Society. Printed anonymously, it became a sensation in Russia and Europe alike. Giving the formal reason of responding to A. de Custine’s La Russie en 1839, Vigel’s brochure served as the first manifesto and the first attempt at a historical-philosophical justification of the anti-German sentiment espoused by members of the Russian elite during the reign of Nicholas I. In his overview spanning the early epochs and the contemporary period, Vigel describes Russia’s whole history in terms of the gradual subjugation by Germans (in particular, Baltic Germans) and their growing representation among the ruling elite. The same viewpoint is applied to the analysis of Russian literature, especially Pushkin, who is depicted as an opponent and eventually a victim of the German party. In the conclusion of his work, Vigel shares his thoughts on contemporary Germany and Pan-Slavism.
Sebald, W. G. (2020). Campo santo. Translated by N. Fyodorova. Moscow: Novoe izdatelstvo. (In Russ.)
Authors: Egorova L. V.
Published: September 2022

The review is concerned with the posthumous collection of Sebald’s hitherto unpublished works: prose pieces about Corsica, initial draft   of his publications in periodicals, speech transcripts, and handwritten notes. The main themes are oblivion and memory, a personal relationship with the past, and the ways of fighting non-existence. Sebald addresses the most poignant issues and heart-wrenching traumas, while his stylistic mastery ensures a bitter and sobering but at the same time very enjoyable kind of reading. Sebald’s rational and crystal-clear rgumentation is irresistible. His style may vary depending on the type of writing (prose — scholarly papers — essays), but every piece is perceived as an outcome of his personal suffering. What prompted each of the works in this collection devoted to conquering time and decay through writing was the struggle against oblivion. Only what has been said or written may escape disintegration. Memory alone offers a chance to overcome alienation.
Voskresenskaya, M. (2020). The sociocultural dimension of the Russian Silver Age. St. Petersburg: SPbGU. (In Russ.)
Authors: Yushkova E. V.
Published: September 2022

In her monograph, M. Voskresenskaya attempts to examine the Russian Silver Age as a historian and a scholar of culture. That perspective is made clear by the book’s title: it points to a sociocultural dimension, so, instead of analysing specific works created during the aforementioned period, she focuses on the society that provided the context for certain cultural and artistic processes. The author undertakes a sociocultural study of the environment in which works emerged that are so famous today, and devotes a whole chapter to the philosophy espoused by the cultural elite. Voskresenskaya also tackles the political agenda — starting with a characteristic of the search for ways to reform the world, she moves on to describe the choice made by the period’s artists, poets and writers to take part or refuse participation in the war and the revolution, and their perception of these two events. Employing the methods of cultural history studies, Voskresenskaya is painting a group portrait of the cultural icons of the Russian Silver Age.
Kholikov, A. and Orlova, E., eds. (2021). Russian literature and journalism during the pre-revolutionary period: Forms of interaction and analysis methodology: A co-authored monograph. Moscow: IMLI RAN. (In Russ.)
Authors: Elina E. G.
Published: September 2022

The book’s three parts feature studies, publications and supplements which include contents descriptions of the newspaper Nov, the journal Bogema, and archival materials connected with the newspaper Russkoe Slovo. It is for the first time that a co-authored monograph has brought together authors united by their study of the fundamental question about the role of fiction in the shaping of the Russian cultural and social landscape ahead of the calamity that was revolution. The book discusses the following topics: the balance between fiction and journalism, the journal context and the methods of its study, the interconnectedness of artistic texts against the background of journalistic output, the perception of literature and its various modifications in central Russia and the country’s periphery, the literary trends that emerged at the turn of the century and their influence on the contents and aesthetic programs of periodicals, and journalists as fictional characters.
Management of Cerebropontine Angle Tumors on Total Intravenous Anaesthesia Facilitating Neuromuscular Monitoring: A Retrospective Observational Study
Authors: Panse Neha A. , Panse Neha A. , Bhoi Nikhil , Pandey Aparajita , Dhananjay Tikait Priyanka
Published: September 2022

Background: With the increasing trend of IONM in neurosurgery the role of total intravenous anaesthesia has gained upper hand in the practice of neuro anaesthesia. Propofol based TIVA techniques facilitates rapid recovery of consciousness and psychomotor function with lower incidence of post-operative nausea and vomiting. It also facilitates satisfactory IONM monitoring while maintaining the adequate depth of anaesthesia. Available literature focuses on the surgical aspects with IONM. Few studies are available, which compare TIVA with general anaesthesia that too without IONM. Earlier TIVA for IONM has been studied in patients undergoing kyphoscoliosis correction surgery. This study was conducted to evaluate the efficacy of TIVA in facilitating IONM in resection of intracranial masses and to study its effects on hemodynamics and post op recovery.
Methods: In our retrospective study of 23 cases, patients undergoing intracranial tumor mass excision surgeries requiring IONM were given standardized general anaesthesia using intubating dose of short acting muscle relaxant and further maintenance of anaesthesia was done using infusion of propofol and dexmeditomidine with the minimal inhalational agents. IONM was recorded successfully.
Results: 18 patients were haemodyanamically stable. 3 patients had intermittent episodes of bradycardia, and 2 patients had hypotension. Three patients elicited dampened response requiring reduction in anaesthetic dose. Six patients exhibited delayed recovery.
Conclusion: TIVA with propofol and dexmeditomidine is a good anaesthetic modality to facilitate IONM in resection of intracranial masses.
YOLOv3, YOLOv4 ve YOLOv5 algoritmalarının Performans Karşılaştırması: Kümes Hayvan Tanıma İçin Bir Vaka Çalışması
Authors: KIVRAK Oğuzhan , GÜRBÜZ Mustafa Zahid
Published: September 2022

Bu çalışmanın amacı, görüntüleri sınıflandırmak için kullanılan popüler evrişim sinir ağı modellerinin arasındaki performans farklılıklarını bulmaktır. Bunun için, YOLO modelinin farklı versiyonları üzerinde bir vaka çalışması yürütüldü. Bu çalışma için yeni bir veri seti oluşturulmuştur. Oluşturulan veri setinde, 918 adet tavuk, horoz ve civciv görüntülerini içeren kümes hayvanı fotoğrafları bulunmaktadır. Veri kümesinin % 80'i eğitim % 20 test olarak ayrılmıştır. Eğitim ve test veri kümelerindeki kümes hayvanlarının görüntüleri manuel olarak etiketlendi. Eğitim veri kümelesindeki görüntüler YOLOv3-tiny, YOLOv3, YOLOv4-tiny, YOLOv4, YOLOv5s, ve YOLOv5x modelleri kullanılarak eğitim tamamlandı. Kümes hayvanı tespiti için YOLOv5' modeli ile elde edilen sonuçlar diğer popüler CNN mimarisi sahip olan YOLOv3 YOLOv4 modelleri ile karşılaştırılmıştır. Sonuç olarak YOLOv5x(XLarge Depth(derinlik)) modeli 0,5 IOU'da %99,5 ortalama hassasiyetle en yüksek doğruluk oranı bulunmuştur.
Development of Jensen Haise Method Reference Evapotranspiration Estimation Equations Suitable for Black Sea Region Climatic Conditions
Authors: USTA Selçuk
Published: September 2022

In this study, it is aimed to determine the usability level of the original equation (JH_original) of the Jensen Haise method in the monthly average reference evapotranspiration (ETo) estimations in the Black Sea Region conditions and to calibrate it in accordance with the local climatic conditions. First of all, the climate classification of the region was made according to the De Martonne aridity index method. Then modified Jensen Haise (JH_modified) equations were developed for each climate class, using the Microsoft Excel program solver add-on. ETo calculations were made using monthly average temperature, relative humidity, wind speed and sunshine duration data (1927 – 2020) of the cities in the region. The ETo values estimated by the JH_original and JH_modified equations were compared with the values determined using the FAO 56 Penman Monteith (PM) equation. While the eastern part of the region is in the very humid climate class, the climate has changed to humid and semi humid towards the west along the coastline. It has been observed that the semi arid – humid climate is dominant in the interior parts, which receive less precipitation compared to the coastal part in region. The annual average ETo values obtained with FAO 56 PM for very humid, humid, semi humid and semi arid – humid conditions were determined as 1.779 mm day-1, 2.349 mm day-1, 2.280 mm day-1 and 2.631 mm day-1, respectively. For the same climate classes, the values estimated with JH_original were obtained as 2.146 mm day-1, 2.697 mm day-1, 2.566 mm day-1 and 2.562 mm day-1. The values estimated using JH_modified were determined as 1.775 mm day-1, 2.319 mm day-1, 2.238 mm day-1 and 2.629 mm day-1, respectively. The MAPE for the ETo values estimated using JH_original varied between %19.357 – 45.561 on the basis of city. Although the accuracy of ETo values is “acceptable” (MAPE= 20 – 50%), JH_original performed poorly in all climate class conditions. For this equation, the MAE, which changed between 0.428 – 0.596 mm day-1 on the basis of climate class, decreased by 62.14 – 92.76% after calibration and regressed to 0.031 – 0.205 mm day-1 range for JH_modified. JH_modified showed the best and worst performances in very humid (MAPE= 2.298%) and semi humid (MAPE= 13.631%) conditions, respectively. Its performance in humid and semi arid – humid conditions was close to each other (MAPE= 8.937 – 9.012). The accuracy of the ETo values estimated using this equation was determined as “good” (MAPE= 10 – 20%) in semi humid conditions and “very good” (MAPE= ≤ 10%) in other climate class conditions. It was concluded that the JH_modified equation is a good alternative and can be used to estimate ETo in humid conditions İn the absence of sufficient data for FAO 56 PM.
Examination of Candidate Teachers' Perceptions of Teaching Quality Competence in Terms of Gender and Faculty Type
Authors: ARI Cüneyt , KARDAŞ Faruk
Published: September 2022

This study aims to examine the candidate teachers’ perceptions of teaching quality competence in terms of gender and faculty type. It is important to raise society which adapts to developments in science and technology in this information and technology age. The quality of education provided in educational institutions is at the forefront of achieving this goal. 346 candidate teachers from an education faculty and pedagogical formation training program in 2019-2020 academic year, participated in the study. “Perceptions of Competency in Teaching Quality Scale” which is a five-point Likert scale with 22 items and developed by Atar and Taşçı was used as data collection instrument. When the data were analyzed, it was found that the role of education faculties in terms of whether the teaching profession was innate or acquired later was revealed. It was also determined that there are significant differences in the perceptions of teaching quality competence of the variables of acquiring and changing behaviors towards the teaching profession between the groups. The teacher candidates who received pedagocigal formation training had a higher perception of teaching quality competence than the teacher candidates in the education faculty. There was no significant difference between the groups in terms of gender variable regarding teaching quality competence perception.
Innovative technologies in dispersion of drilling washing liquids for drilling and development of oil and gas wells
Authors: Kuznetsov Yu. S. , Averyanov A. P. , Bastrikov S. N. , Ovchinnikov P. V. , Sultanov D. R. , Urmancheev V. I.
Published: September 2022

The article presents the results of comprehensive studies of the effect of wave technologies on the physico-mechanical properties of finely dispersed montmorillonite suspensions and supersaturated salt solutions in laboratory and field conditions. It is shown that because of wave processing by flow hydrodynamic vortex-type generators with tangential and radial channels and flat-type generators with cylindrical flow bodies, the dynamic shear stress of clay solutions has increased significantly, the number of solution particles with a size of 1-2 microns has increased 2.5 times. This means that the wave treatment of the clay suspension leads to an increase in the colloidal fraction, and, consequently, to an increase in the quality of the suspension, to a decrease in the consumption of clay powder, as well as to a several-fold reduction in the preparation time compared to traditional technology. As a result of wave treatment of supersaturated salt solutions, the degree of dispersion also increased significantly: the size of salt particles in the su-persaturated solution is from 120 microns when using a conventional mechanical stirrer, and after treatment with a wave generator is 1-6 microns. It is shown that the main contribution to the achievement of high efficiency of wave processing is made by nonlinear wave and cavitation processes occurring in the flow part of hydrodynamic generators.
Left in the Cold
Authors: Whitehouse Bruce
Published: September 2022

Located in Africa’s Sahel region, the Republic of Mali enjoyed various fruits of its transition to political pluralism and liberal economic restructuring from the 1990s to the early 2000s. When the Malian government sought to amend civil laws governing marriage and family life, and eliminate legal discrimination against women, however, it faced considerable political opposition. Islamic civil society groups capitalised on men’s heightened anxieties to claim a more assertive role in the national public sphere. Subsequent legal reforms constituted a clear political victory for political Islamism in the country and a corresponding setback for Western-backed women’s organisations. Tracing the evolution of Malian marriage and family law from the 1960s to the 2020s, this article argues that conflicting notions of what it means to protect women, coupled with the structural failings of Mali’s post-colonial state, have stymied efforts to ensure women’s rights within a secular, egalitarian legal framework.
Development of Machine Learning-Based Model for Quality Measurement in Maternal, Neonatal and Child Health Services: A Country Level Model for Tanzania
Authors: Nyanjara Sarah , Machuve Dina , Nykänen Pirkko
Published: September 2022

Background: The high maternal and neonatal mortality in developing countries is frequently linked to inadequacies in the quality of maternal, neonatal, and child health (MNCH) services provided. Quality measurement is among the recommended strategies for quality improvement in MNCH care. Consequently, developing countries require a novel quality measurement approach that can routinely facilitate the measurement and reporting of MNCH care quality. An effective quality measurement approach can enhance quality measurement and improve the quality of MNCH care. This study intends to explore the effectiveness of approaches available for MNCH quality measurement in developing countries. The study further proposes a machine learning-based approach for MNCH quality measurement. Method: A comprehensive literature search from Pub Med, HINARI, ARDI, and Google Scholar electronic databases was conducted. Also, a search for organizations' websites, including World Health Organization (WHO), USAID's MEASURE Evaluation Project, Engender Health, and Family Planning 2020 (FP2020), was included. A search from databases yielded 324 articles, 32 of which met inclusion criteria. Extracted articles were synthesized and presented. Findings: The majority of quality measurement approaches are manual and paper-based. Therefore are laborious, time-consuming and prone to human errors. Also, it was observed that most approaches are costly since they require trained data collectors and special data sets for quality measurement. It is further noticed that the complexity of the quality measurement process and extra funds needed to facilitate data collection for quality measurement puts an extra burden on developing countries that always face constraints in health budgets. The study further proposes a machine learning-based approach for measuring MNCH quality. In developing this model, financial and human resource constrain were considered. Conclusion: The study found a variety of quality assessment approaches available for quality assessment on MNCH in developing countries. However, the majority of the existing approaches are relatively ineffective. Measuring MNCH quality by a machine learning-based approach could be advantageous and establish a much larger evidence base for MNCH health policies for Tanzania.
E-Formation Policy in Developing the Need for Civil Servants in the Probolinggo Regency of Indonesia
Authors: Handayani Dewi , Sadhana Kridawati , Wiyani Wahyu
Published: September 2022

Based on the regulations, the preparation of employee needs is carried out using an electronic application. E-Formation from the rationale to speed up the administrative process and ensure the accuracy of data related to job maps, number of employees, employee placement positions, allocation of shortages and excess employees. In preparing formation requirements, civil servants in every Ministry, State Institution and Government Agency, both central and local, are required to use this system, and the deadline for completing the e-formation is according to the schedule determined by the centre. This study aims to describe: the implementation of civil servant formation through e-formation in the Probolinggo Regency and the supporting and inhibiting factors with the implementation of civil servant formation through e-formation in the Probolinggo Regency. This study uses a qualitative approach with a descriptive type. The results of the study show: The Probolinggo Regency Government has implemented a Government policy that prepares civil servant formation requirements using an e-formation application based on job maps, job analysis and workload analysis contained in the regent's Regulation. However, with the simplification of the bureaucracy and the equalization of structural positions to available positions, the Probolinggo Regency Government should re-evaluate the Regent's Regulation; and In carrying out the preparation of civil servant formation needs, it is necessary to have support from the leadership in Probolinggo Regency to overcome inhibiting factors such as budget allocation, increasing the competence of formation builders, mutation/transfer of employees and delegation of tasks/responsibilities.
Development of Navigation System for Blind People based on Light Detection and Ranging Technology(LiDAR)
Authors: Felix Faith , S. Swai Rodrick , Dida Dr.Mussa Ally , Sinde Dr.Ramadhani
Published: September 2022

The use of blind-aided navigating systems has become very essential in the 4th industrial revolution. The essence of this is to improve navigating autonomy for the blind. Although, navigation challenges are not of serious concern to people with eye defects. However, this is a major concern for blind people due to the time-consuming navigation process. These limitations necessitate the use of walking sticks, dogs, or people to navigate their path. This project provides a blind navigation system based on Light Detection and Ranging Based Navigation System for Blind People (LiDAR). The components of this fabricated device involve a charging system, a LiDAR sensor, a microcontroller, a calling stick, two buzzers, a switch vibration motor with an RF transmitter, and a receiver to give object detection and real-time assistance to the blind. The mode of its operation is by detecting obstacles along the route of a blind person and giving a notification via the buzzer and the vibration motor. Also, during emergencies, the buzzer rings and informs the visually impaired person using the device. On the other hand, the microcontroller and other modules in the device have a continuous ongoing relationship which is beneficial to the user. Another appreciable benefit of this device is the ability to recharge the battery component, the device is of low-cost, quick, simple-to-use, and novel solution for the blind.
Overview of Integrated Population Administration Services at the Probolinggo Regency's of Indonesia
Authors: Fatimah  , Sholahuddin Agus , Sadhana Kridwati
Published: September 2022

Population administration fulfils administrative rights, such as public services and protection related to population documents, without discriminatory treatment. Population administration is the service of all population documents by the Presidential Regulation concerning the requirements and procedures for population and civil registration. However, public awareness of the importance of population documents is still deficient; economic conditions and the distance of people from their domiciles, especially those in remote areas/difficult areas, so that there are still many residents who do not have population documents. With integrated services carried out by the Population and Civil Registration Office of Probolinggo Regency, it aims to provide more effective, efficient, fast, and complimentary services. This study aims to describe and analyze population administration services integrating birth certificates, family cards, and child identity cards based on minister of Home Affairs Regulation concerning population administration services at the Probolinggo Regency Population and Civil Registration Service and the obstacles in its implementation. This study uses qualitative methods through observation, interviews, and documentation. The analysis results show that the integrated population administration service has so far been able to adapt to new policies that require using the latest applications in population administration services. More than 1 million residents of Probolinggo Regency who cannot reach population administration service facilities offline and online can be reached and complete the application for population administration and have been facilitated to completion. Besides that, The obstacles faced from the inner side include the policy of refocusing the budget, lack of facilities and infrastructure, and human resources. Meanwhile, the outer side, including the elderly, who lack technology understanding and disabilities, require special officers and internet network disturbances
Підлітковий вік та цукровий діабет 1-го типу: виклики для кісткової системи та ступінь забезпеченості вітаміном D
Authors: Biliaieva K.S. , Vlasenko M.V.
Published: September 2022

Ведення пацієнта з цукровим діабетом 1-го типу (ЦД1) підліткового віку є складним завданням, що пов’язано з механізмами гормональної перебудови, які притаманні даному пубертатному періоду. Враховуючи світові дані щодо перебігу молекулярних механізмів за участю активного метаболіту вітаміну D у процесах росту і розвитку організму, наявність рецепторів вітаміну D у багатьох тканинах організму, а саме в β-клітинах підшлункової залози, надзвичайно актуальним є не лише вивчення впливу рівня вітаміну D на перебіг ЦД1, а й оцінка стану кісткової системи в підлітків, які мають порушення вуглеводного обміну. Мета: оцінити перебіг ЦД1 на фоні недостатності чи дефіциту вітаміну D і проаналізувати стан кісткової системи в підлітків, які хворіють на ЦД1. Матеріал і методи: обстежено 124 дитини віком від 10 до 18 років, включаючи 91 дитину, які хворіють на ЦД1 (1-а група), а також 33 соматично здорових підлітки (2-а група). Рівень вітаміну 25(ОН)D у крові визначався за допомогою імуноферментного аналізу на аналізаторі «Cobas е 411» («Roche Diagnostics International Ltd», Німеччина). З метою оцінки стану кісткової системи в підлітків була проведена подвійна енергетична рентгенологічна абсорбціометрія. Оцінка стану кісткової системи проводилась за ступенем зниження кісткової маси (показник Z-score). Результати. Аналіз показника Z-score в підлітків встановив вірогідно нижчі значення мінеральної щільності кісткової тканини (МЩКТ) у хворих на ЦД1 порівняно зі соматично здоровими підлітками як серед дівчаток, так і серед хлопчиків (р<0,05). Частота виявлення дефіциту вітаміну D серед підлітків, хворих на ЦД1, вдвічі перевищувала частоту його дефіциту в підлітків без порушення вуглеводного обміну. Структурно-функціональні зміни кісткової тканини вірогідно залежали від ступеня недостатності вітаміну D у підлітків, хворих на ЦД1, незалежно від статі. Висновки. Визначення наявних структурно-функціональних змін кісткової системи та ступеня забезпеченості вітаміном D серед підлітків, хворих на ЦД1, є необхідною складовою оцінки кісткового метаболізму в період набору піку кісткової маси. Ступінь недостатності вітаміну D у підлітків, хворих на ЦД1, впливає на ступінь компенсації захворювання.
Антиандрогени, наночастинки та біоактивні пептиди: експериментальні та клінічні питання
Authors: Reznikov A.G.
Published: September 2022

Оглядова стаття підсумовує основні результати екс- периментальних досліджень співробітників лабораторії нейрогормональної регуляції розмноження та відділу ендокринології репродукції та адаптації стосовно біологічних ефектів нестероїдних антиандрогенів, наночастинок металів, біоактивних пептидів та їх імплементації в різних галузях медицини. Досліджено фармакодинамічні ефекти і фармакокінетику ніфтоліду (флутаміду) та інших синтезованих в інституті антагоністів рецепторів андрогенів із групи заміщених карбоксанілидів. На цьому підгрунті запропоновано новий метод функціональної діагностики гонадотропних резервів гіпоталамо-гіпофізарно-тестикулярної системи та створено лікарські засоби для лікування гірсутизму, синдрому полікістозних яєчників, раку передміхурової залози. Проведено їхні доклінічні дослідження та впровадження в клінічну ендокринологію, онкологію, гінекологію, дерматологію. Експериментально обгрунтовані та підтверджені онкоурологічною практикою концепція оптимальної андрогенної блокади та метод низькодозової естроген-антиандрогенної паліативної та неоад’ювантної терапії раку передміхурової залози та його метастазів. Розроблено і впроваджено спосіб підвищення ефективності гонадотропної стимуляції овуляції в циклах допоміжних репродуктивних технологій. Виявлено пригнічуючий вплив полідисперсного колоїдного розчину наночастинок золота (10-50 нм) на ріст ксенографтів андрогензалежного раку передміхурової залози людини, трансплантованих під капсулу нирки мишей. Препарат зменшував кількісне співвідношення епітеліальних клітин ксенографтів до строми, а в дослідах in vitro пригнічував проліферацію ракових клітин простати LnCaP і частково блокував стимулювальний ефект 5-альфа-дигідротестостерону на ріст культури. У дослідах на старіючих щурах виявлено стимулювальний ефект перорального введення наночастинок діоксиду церію (2-3 нм) стосовно сперматогенезу та секреції тестостерону. Досліджено вплив рекомбінантного поліпептидного цитокіну EMAP II (endothelial-monocyre activating polypeptide II) та його нанокомпозитів на ріст ксенографтів андрогензалежного раку передміхурової залози людини в мишей. Ін’єкції EMAP II гальмували ріст ксенографтів, викликали в них цитотоксичний ефект та запальну реакцію. Флутамід посилював протипухлинну дію EMAP II. У дослідах на культурі LnCaP спостерігали проапоптотичний та антипроліферативний ефекти препарату. Отримані результати експериментальних досліджень створюють підгрунтя для розроблення нових методів лікування андрогензалежного раку передміхурової залози з використанням нанометалів і біоактивних пептидів.
Застосування біологічно активних речовин у стоматологічній практиці: досвід і перспективи (огляд літератури)
Authors: Kindrat G.V. , Kindrat I.P. , Rozhko M.M.
Published: September 2022

У статті проаналізовано дані літератури з приводу негативного впливу антропогенних чинників на стан здоров’я дитячого населення та способи і методи його корекції з метою оздоровлення організму. Мета роботи. Проаналізувати й систематизувати дані наукових досліджень щодо негативного впливу антропогенних чинників на стан організму дитини та способи оздоровлення. Висновок. Аналіз літературних джерел показав шкідливий вплив різних антропогенних чинників на стан здоров’я дитячого населення, у подальшому на формування захворювань у дорослих осіб. У наукових дослідженнях обґрунтовано методи й засоби профілактики негативної дії несприятливих умов на організм і ротову порожнину шляхом застосування біологічно активних речовин.
Морфологічні та функціональні зміни печінки при експериментальному цукровому діабеті на 56-ту добу експерименту
Authors: Bodnarchuk Yu.V.
Published: September 2022

Цукровий діабет є одним із найпоширеніших захворювань ендокринної системи. Незважаючи на те, що значна кількість наукових робіт присвячена питанням патогенезу та лікуванню діабету, це захворювання все ще залишається значною медико-соціальною проблемою сьогодення. Тому встановлення особливостей морфофункціональних змін у печінці щурів при стрептозотоциновому ЦД є актуальним. За даними світлооптичних і ультраструктурних досліджень, у печінці нестатевозрілих щурів на 56-ту добу експерименту є найбільше молодих (темних) гепатоцитів, якіхарактеризуються: щільною цитоплазмою, великою кількістю молодих мітохондрій, достатньою кількістю гранул глікогену, гіпертрофованими гранулярною і гладкою ендоплазматичними сітками. Для дослідження використано щурів-самців лінії Вістар 3-міс. (масою 80-100 г), яких було розподілено на 2 групи. До першої групи увійшло 10 тварин, яким моделювали експериментальний стрептозотоциновий цукровий діабет одноразовим внутрішньоочеревинним введенням стрептозотоцину, попередньо розведеного в 0,1 М цитратному буфері з рН 4,5, із розрахунку: 7 мг/100 г маси тіла тварини. До другої (контрольної) групи увійшло 10 тварин, яким в еквівалентній дозі внутрішньоочеревинно вводили 0,1 М цитратний буфер із рН 4,5.
COVID-19 Pandemisi Sırasında Anti Romatizmal İlaçlara Halkın İlgisi: Türkiye’deki Google Trends Analizi, Kesitsel Çalışma
Authors: YÜCESOY Hidayet , ATMACA AYDIN Ebru , KARAARSLAN Fatih
Published: September 2022

Amaç: COVID-19 pandemisi sırasında halkın anti-romatizmal ilaçlara olan ilgisini, Google verilerini kullanarak araştırmak.

Gereç ve Yöntemler: Nonsteroid anti-inflamatuvar ilaçlar (NSAİİ), glukokortikoidler, antigut ajanlar, konvansiyonel hastalık modifiye edici anti-romatizmal ilaçlar, immünsupresif ajanlar, interlökin (IL)1-6-17 inhibitörleri, tümör nekrozis faktör inhibitörleri gibi anti-romatizmal ilaçlarla ilgili arama terimlerini seçtik. Google Trends’te, belirlenen 78 arama sorgusu için Türkiye’de 15/03/2016 -26/12/2020 zaman aralığında ve "Tüm kategoriler" içinde arama yaptık. ‘15 Mart-4 Temmuz’ ve ‘5 Temmuz-26 Aralık’ zaman aralıklarını, önceki 4 yılın (2016-2019) aynı zaman aralıkları ile kıyasladık.

Bulgular: COVID-19 pandemisinin başlangıç dönemini, önceki 4 yıl ile karşılaştırdığımızda; 78 arama sorgusundan 15 tanesinin (Advil, Brufen, diklofenak, Cataflam, Voltaren, Dolorex, Naprosyn, Apranax, Melox, Exen, Kolşisin, hidroksiklorokin, Plaquenil, Arava, Actemra) istatistiksel anlamlı artış, 21 tanesinin anlamlı azalma gösterdiğini gözlemledik. İlerleyen dönemde ise, 78 arama sorgusundan 19 tanesinin ( ibuprofen, Brufen, Cataflam, Voltaren, Dolorex, Naprosyn, Apranax, Melox, Exen, Prednol, Dekort, Kolşisin, Kolsin, hidroksiklorokin, Plaquenil, tosilizumab, Actemra, anakinra, Kineret) istatistiksel anlamlı artış, 17 tanesinde anlamlı azalma gösterdiğini gözlemledik.

Sonuç: COVID-19 pandemisinin erken ve ilerleyen döneminde; NSAİİ grubu arama sorgularının çoğunluğunda, hidroksiklorokin ve ticari ismi Plaquenil’in, tosilizumab ve ticari ismi Actemra’nın arama hacminde istatistiksel anlamlı artış saptanmıştır. Her iki dönemde de arama hacmi azalan ilaçlar çoğunlukla immunsupresif ilaçlar ve biyolojik ajanlar kategorisindedir. Bu bulgular, halkın COVID-19 tedavisiyle ilgili bilgi edinmek istediğini ve internette araştırma yaptığını düşündürmektedir. Halkın gereksinimlerini anlamak ve gerekli bilgilendirmeleri yapmak, sürecin yönetiminde yararlı olabilir.
Membangun Jati Diri Suku Tehit Kabupaten Sorong Selatan Papua Barat
Authors: Flassy Marlina
Published: September 2022

This article aims to analyze the identity construction of the Tehit tribe in Sorong Regency, West Papua Province. This study used a qualitative method with an ethnographic approach. The determination of informants is determined purposively, by selecting influential figures, both traditional and educational figures. The data collection technique used was in-depth interviews. Then data analysis includes the stages of data categorization, data description, and data interpretation. The results showed that the sense of identity of the Tehit tribe experienced degradation internally and externally due to practical politics and economic competition so that relations between people became loose. For this reason, the strategy developed in constructing the identity of the Teaite tribe is the socialization of tea culture and strengthening solidarity between groups, by revitalizing traditional institutions and carrying out cultural events to arouse the spirit of ethnicity of the Tehit tribe, as well as revitalizing claims to customary forests as customary rights as part of defending their identity. the Tehit tribe. then, educate among community groups and regenerate them to occupy strategic positions. Therefore, the technical culture must be made in a written document and visualized so that continuous research is needed to be included in the preparation of the Regional Budget (APBD) of South Sorong Regency
Peran Dewan Adat Suku Sentani untuk Penyelesaian Konflik Kekerasan dalam Rumah Tangga
Authors: Sanggenafa Christine O. I. , Hidayana Irwan Martua
Published: September 2022

This article aims to describe and analyze the role of the Sentani Ethnic Council in the resolution of domestic violence experienced by Sentani women. Sentani society acknowledges that Sentani Tribal Council established in has several functions in political, economic, legal, security, and religious affairs. This study focused on the Sentani Tribal Council as a legal institution in solving domestic violence against Sentani women. The research problem is what factors encourage Sentani women to choose to resolve domestic conflicts through Sentani Tribal Council. This is a qualitative research that employed in-depth interview techniques and observation in the Sentani Ethnic Council courts. Interviews were carried out to victims of domestic violence, head of tribal council, and community leaders, domestic violence doer, and Sentani people. Sentani women who were victims of domestic violence went to the Sentani Ethnic Council to solve their problems due to several reasons, namely peaceful court, customary fine, and avoiding shame. There is a change in the customary fine from certain goods to rupiah currency. Although Sentani women obtained conflict resolution in the Sentani Ethnic Council, it did not provide justice yet. There are different views on domestic violence in Sentani. Some parties local government, church, tribal council, women, and victim perceived that domestic violence is violating human rights, therefore, must be sentenced. While the doers and young men in Sentani perceived that violence against women is common in their culture. From an anthropological perspective, domestic violence in Sentani is a debate between culture and rights in the context of cultural relativism.
Perubahan Fungsi Tarian Tummour Pada Suku Mbaham Matta
Authors: Hindom Reni F , Yuliana Yuliana , Wenehen Agustinus
Published: September 2022

This article aims to describe and analyze the changes in the function of the Mbaham Matta tribe's ‘tummour’ dance in the past and the present and to find out what efforts were made to be able to maintain the ‘Tummour’ dance of the Mbaham Matta tribe in Fakfak Regency in general. This research is qualitative using data collection techniques through interviews, observation, and documentation. The research results show that the ‘tummour’ dance in the past was used as traditional rituals, traditional parties, to gather the masses, to summon ancestral spirits, to dance the victory of the war and to stem the coming dangers. The change in the function of the ‘tummour’ dance occurred because of the entry of religion and government. Changes that occur are not only in the function of the ‘tummour’ dance, but the attributes used have also changed. Then, the efforts made so that the ‘Tummour’ dance can survive include opening a dance studio and preserving the ‘Tummour’ dance through socialization (transfer of knowledge) or introducing it to the younger generation.
Perkawinan Usia Dini Perempuan Korowai di Kampung Kabuage Distrik Firiwage Kabupaten Boven Digoel
Authors: Kenelek Sarova , Poli Agustina Ivonne , Frank Simon Abdi K.
Published: September 2022

This study aims to determine the form of early marriage among Korowai women and want to know the factors that influence the occurrence of early marriage for Korowai women in Kabuage village, Firiwage district, Boven Digoel district. The research method used is descriptive-qualitative method, because this method is considered capable of analyzing social reality in detail. Research informants include women who marry early, traditional parents, men and the village head. Data collection was carried out using literature study and field study techniques which included observation, interviews and literature studies. In analyzing the data, three lines of interactive analysis were used, namely data reduction, data presentation and conclusion drawing. The results showed that there were two forms of early marriage in women, namely the form of coercion and without coercion and the driving factors for early marriage in women in Kabuage Village were cultural, educational, economic and modernization factors. The conclusions and suggestions of this study are that early marriage among Korowai women in Kabuage Village, Firiwage District, Boven Digoel Regency occurs in the form of coercion and without coercion which generally occurs due to cultural, educational, economic and modernization factors. Then the suggestion that can be given is the need for the involvement of the Office of Women Empowerment and Family Planning (KB) in Boven Digoel Regency to suppress marriage at an early age. So, it can provide a good understanding to parents, community and traditional leaders. As well as creating more opportunities for girls to obtain rights in accordance with the Rights of the Child Convention. As well as the need for the efforts of various agencies to work together to help human resources in Kabuage Village.