bluuebunny/crossref_metadata_2025 huggingface dataset:
Eco-Tourism: Concepts and Application by Smart Rural Areas: Case Study in Trenggalek, East Java
Authors:   Faculty of Engineering, University of Udayana, Bali Province, Sri Aryani Ni Wayan , Octa Yuniarsa Sherlinda ,   Faculty of Economic and Business, University of Brawijaya
Published: December 2022

Indonesia has a good tourist market, East Java is an island that has a very magnificent of tourism potential, then Trenggalek is particular as a tourist-magnet in South East Java. Several southern regions such as Trenggalek appear to play a huge role in sustaining economic growth, especially in the southern coastal areas. This several factors have supported by environment, knowledge, and expertise of the local population through the economy. Particularly in Trenggalek and generally in East Java is to apply the concept of international education with a package tour for tourism development in the short and long term as well. In this case, how to make local people economically profit in the sustaining tourism progress, how to develop eco-tourism programs and products meets the needs of tourist market and how to promote the concepts of cultural education. The methodology use a site visits with capability to quickly act and growth some innovation. The results of this study provide some several choices of answers a concepts and applications that be able to show entrepreneur potential in Trenggalek, East Java. Some concepts have 4 components, such as tourism destinations, tourism communication between local people and local government, tourism good services, and also value change. For the over time, local people in Trenggalek area will be more confident displaying their expertise. They can introduce about how to develop culture through creative learning programs with domestic tourists. There is a flow chart for some tourists to get a location using a smart village technology, it learn together about tourism for business, such as making business processed by making batik (culture), and learning for java language (education). So, some concepts and applications it can joined by local citizens, government, and stakeholders to change for ecotourism. Because a survival for ecotourism is depend on earth. Hopefully, an expectation can be applied in East Java by using a smart village, specifically for tourists to increase a economic growth.
Discovery of large mangrove-dwelling Elysia species in the newly-grown mangrove habitats, Pattani, Thailand
Authors: Buatip Somsak , Saengkeaw Supaporn , Buatip Supakan
Published: December 2022

The first report on the occurrence of the remarkable and highly ephemeral sap-sucking sea slugs Elysia bangtawaensis and E. leucolegnote from the newly grown mangrove forest in the Prince of Songkla University, Pattani, Thailand. Elysia was surveyed by exploring from the inner part to the floor front zone of the mangrove area. The various sizes and numbers of E. bangtawaensis were clumped distribution in some microhabitats throughout the area, while E. leucolegnote was distributed in the floor front zone of the area. Both species have similar external morphological characters with conspecifics previously reported in Pattani Bay, Gulf of Thailand, Andaman Sea, and elsewhere. E. bangtawaensis showed a surprisingly larger size than previously reported. This discovery is important in identifying the changes in ecosystems within the area to support the diversity of organisms that will come to use the area in the future.
The emerging evidences related to the Inter-relationship between COVID-19 and climate change: A scoping review perspective
Authors: Mohamed Shaffril Hayrol Azril , Abu Samah Asnarulkhadi , Samsuddin Samsul Farid , Sahharon Hamizah
Published: December 2022

Coronavirus Disease 2019 (COVID-19) has affected a number of integral aspects and climate change is one of them. The inter-relationship between COVID-19 and climate change has garnered the interest among scholars across the globe to probe into the related emerging issues. With the escalating number of published articles, a pressing need is present to map and review all available studies in order to capture comprehensive and organised views for future scholars to draw upon the existing pattern of the interchanging correlation between COVID-19 and climate change. This scoping review is guided by a primary research question - what is the inter-relationship between COVID-19 and climate change. Related articles and documents were retrieved from Scopus, Science Direct, and Google Scholars databases. The thematically analysis data were classified into four emerging themes: (1) reduced air pollution, (2) low carbon emission, (3) the impact of temperature and humidity variation on COVID-19, and (4) the impact of air pollution on COVID-19. Variances in the outcomes, particularly on the effects of temperature, humidity, and polluted air on COVID-19, suggest further exploration endeavours. Essentially, the economic impact exerted by COVID-19 and its overall effect on budget to combat climate change remain untapped.
RECATEGORIZAÇÃO E ARGUMENTATIVIDADE:
Authors: De Souza Soares Luz Gomes Kelli Roberta , De Morais Diógenes Bezerra Lidiane
Published: December 2022

As reflexões mais recentes sobre os processos referenciais recategorizadores têm reforçado a sua dinamicidade e evidenciado a relevância discursiva que apresentam para a composição de variados gêneros. Nesse sentido, a força argumentativa dessas construções anafóricas para o texto mobiliza estudos como este, que procuram numa teoria da argumentação um reforço para a compreensão do fenômeno da recategorização também por essa dimensão. Dessa maneira, objetiva-se com esta abordagem analisar redes referenciais em seções de Análise dos Resultados de monografias, considerando a ocorrência de recategorizações em movimentos retórico-composicionais de traços argumentativos presentes nesses textos. A discussão proposta neste artigo baseia-se nas contribuições de Amossy (2018, 2020), Cavalcante, Custódio Filho e Brito (2014), Cavalcante e Brito (2016), Cavalcante et alli (2020), Matos (2018), Motta-Roth e Hendges (2010) e é resultante da análise de duas seções reservadas à discussão dos resultados de estudos de caso. Pelo empreendimento, reitera-se o efeito que o teor subjetivo de construções recategorizadoras, que expressem interpretação ou juízo de valor de quem escreve, impacta na dimensão argumentativa do texto e, consequentemente, na efetividade do propósito enunciativo esperado para o gênero acadêmico.
Prediction of Heart Disease Using Voted Perceptron
Authors:   Women Scientist, Under WISE KIRAN IPR, TIFAC, DST, India, Naveed S Safia
Published: December 2022

Heart Disease is the most dominating disease which is taking a large number of deaths every year. A report from WHO in 2016 portrayed that every year at least 17 million people die of heart disease. This number is gradually increasing day by day and WHO estimated that this death toll will reach the summit of 75 million by 2030. Despite having modern technology and health care system predicting heart disease is still beyond limitations. As the Machine Learning algorithm is a vital source predicting data from available data sets we have used a machine learning approach to predict heart disease. We have collected data from the UCI repository. In our study, we have used Random Forest, Zero R, Voted Perceptron, K star classifier. We have got the best result through the Random Forest classifier with an accuracy of 97.69.
Medidas de Posición
Authors: Flores Ccanto Florencio , Chirinos Maldonado Daniel Marcos , Gálvez Morales Lourdes , Menacho Vargas Isabel , Dávila Huamán Vicente Carlos , Villegas Lira Marianella Marilu
Published: December 2022

El estudio de las medidas de posición es muy importante dentro del desarrollo de la Estadística Básica; el estudio de la medida de posición tiene que ver con el estudio de Cuartiles, Percentiles y Situaciones de conflicto cognitivo para las diversas aplicaciones prácticas en la resolución de problemas o situaciones didácticas que se presenta al estudiante durante el desarrollo de la clase y este resolución se realiza haciendo uso como material didáctico el emulador Casio fx-570LA-X Classwiz, pero, no es la única herramienta en que se puede utilizar; algunos autores presentan el tema de distintas formas, donde también utilizan herramientas estadísticas como el SPSS y otros. En el presente libro desarrollamos en la estadística básica de Cuartiles y Percentiles haciéndola más sencilla, amena creando y despertando el interés de los estudiantes que llevan la asignatura Estadística aplicada a la investigación en la universidad. El libro termina presentando ejercicios adicionales de situaciones de la vida cotidiana.
Biofármacos usados para o tratamento de artrite reumatoide: uma revisão de literatura
Authors: Vitorino de Souza Neto Alicio , De Oliveira Souza Maurília , Ferreira Andrade Gracielle
Published: December 2022

A artrite reumatoide é uma doença inflamatória crônica de caráter autoimune que tem como principais alvos as articulações, podendo levar à destruição desses tecidos quando não tratada, o que pode resultar na diminuição dos movimentos e na qualidade de vida dos indivíduos afetados. O seu tratamento convencional se baseia na utilização de fármacos antirreumáticos modificadores de doenças (MMCDs), anti-inflamatórios não esteroides e corticosteroides. Porém, com o advento da biotecnologia houve o surgimento dos medicamentos biológicos, que ofereceram uma nova opção de tratamento para a artrite reumatoide. O presente trabalho teve como objetivo realizar uma revisão integrativa por meio de levantamento da literatura em bases de dados científicas para responder à pergunta: “quais são as vantagens e as desvantagens do uso dos medicamentos biológicos em comparação ao tratamento convencional em casos de artrite reumatoide?”. Os artigos foram selecionados com base na data de publicação e quanto à sua relevância para o tema, sendo utilizados os termos biofármacos, medicamentos biológicos e artrite reumatoide como palavras-chave, nos idiomas inglês e português. Artigos que não tinham como foco o tema proposto, seja em seu título, resumo ou texto completo, foram excluídos. Por fim, foram utilizados 82 artigos para a escrita do presente trabalho. Como resultado os artigos apontaram que os biofármacos trouxeram um aumento da quantidade de opções terapêuticas, porém, também apontaram para o alto custo dessa terapia, o que pode ser amenizado com o surgimento dos biossimilares.
Covid-19 pandemisinde Borsa İstanbul'a kote gıda sektörü işletmelerinin finansal performanslarının gri ilişkisel analiz yöntemi ile değerlendirilmesi
Authors: BOZKIR Beyza , YILDIZ Umut Erdem , YILMAZ TÜRKMEN Sibel
Published: December 2022

2019 yılında başlayan ve ardından dünya çapında bir salgın olan COVID-19, küresel anlamda hem ekonomik hem de sosyal açıdan negatif sonuçlar oluşturmuştur. Yaşanan bu gelişmelerden hemen hemen her sektör etkilenmiş olup, Gıda, İçecek ve Tütün Sektörü de bu sektörler arasında yer almaktadır. Çalışma ile ulaşılmaya çalışılan, yaşanan gelişmelerin beraberinde Borsa İstanbul (BİST)’a bağlı Gıda, İçecek ve Tütün Sektöründe yer alan şirketlerin, COVID-19 pandemi dönemini kapsayan 2019-2021 yıllarında nasıl etkilendiklerinin ortaya konulmasıdır. Çalışmada kullanılan yedi adet finansal oran, Kamu Aydınlatma Platformu (KAP)’ndan elde edilen finansal raporlar üzerinden oluşturulmuş; elde edilen oranlar çalışmada uygulanan yöntem olan Gri İlişkisel Analiz kapsamında kullanılmıştır. Uygulama sonucunda ilgili sektördeki şirketlerin yıllar içerisindeki sıralamaları ortaya konulmuş ve değerlendirmeleri yapılmıştır. Araştırmaya göre; bazı şirketlerin bu dönemi avantaja çevirdiği, bazılarının ise değişime karşı yanıt veremediği sonucuna varılmıştır. Pandeminin etkilemediği düşünülen şirketlerin ise güçlü bir finansal yapıya sahip olduğu gözlemlenmiştir.
Lojistik üs olma potansiyeli açısından Sakarya ilinin değerlendirilmesi
Authors: ATEŞ Çağdaş , ESEN Sinan
Published: December 2022

Amaç: Bu çalışmanın temel amacı, Sakarya’nın bir lojistik üs olarak potansiyelinin değerlendirilmesidir. Potansiyele ait belirleyicilerinin sunulması ve lojistik bağlamında mevcut durumunun ortaya konulması hedeflenmektedir.Yöntem: Bu çalışma tür olarak nitel bir araştırmadır ve lojistik üs kriterlerinden yola çıkılarak tümdengelimci yaklaşımla dizayn edilmiştir. İçsel Örnek Olay araştırma desenine sahip olan bu çalışmada veri toplama yöntemi olarak yarı yapılandırılmış görüşme formu ile mülakat yöntemi kullanılmıştır. Verilerin analizi için ise İçerik Analizi’nden faydalanılmıştır. Bulgular: Sakarya lojistik üs potansiyeli anlamında; konum, avantajlı ve baskın taşıma türü, kombine taşımacılığa elverişlilik, pazarlara yakınlık, yatırım teşviki, dağıtım ve toplama ağı, destekleyici ve bağlı endüstriler, lojistik rekabet üstünlüğü, politika ve düzenlemeler, insan kaynakları ve finansal altyapı kriterlerine büyük oranda sahiptir. Gümrük işlemleri, bilgi ve iletişim teknolojileri ve özel dağıtım ve depolama kriterleri konusunda ise dezavantajlara sahiptir.Sonuç: Sakarya’nın lojistik üs olma kriterleri değerlendirildiğinde bölgesel lojistik üs olma potansiyeline sahip olduğu söylenebilir.
Hilenin İşletme Sürekliliğine Etkisi
Authors: YAYLALI İpek , CELAYİR Duygu
Published: December 2022

Rekabetin artması, teknolojik gelişmeler, iş hacimlerinin büyümesi ve faaliyet alanlarının genişlemesi işletmelerde karmaşık bir yapıya zemin hazırlamıştır. Bu gelişmelerin yanında yaşanan finansal sorunlar; işletmelerde hile ve suistimal riskini arttırmış ve sürdürülebilir başarıyı engellemiştir. Hile ve işletmenin sürekliliği kavramı birbiriyle ilişkili kavramlardır. Hile, bir işletmenin önümüzdeki on iki ay boyunca işine devam etme kabiliyetini tehdit edebilir. Yatırımcıların işletmeye olan güvenini zedeler ve başarısızlığına neden olabilir. Bir işletme iflas etme riskiyle karşı karşıya kaldığında veya finansal sıkıntıya düştüğünde, çalışanlardan mevcut ve potansiyel yatırımcılara kadar pek çok paydaş etkilenebilir. Bu açıdan işletmelerin varlıklarını sürdürebilmeleri için “güven” ve “itibar” önemlidir. Güven ve itibarı sarsacak olan ise “hile”dir. Ortaya çıkan hileler işletmelere olan güveni zedeleyerek işletmelerin devamlılığını etkileyebilmektedir. Dolayısıyla, yaşanılan hileler sonucunda birtakım düzenlemelere gidilmiş ve birçok ülkede muhasebe ve denetim alanında işletmeler, sermaye piyasaları, yasa koyucular tarafından denetime yönelik daha sağlam ve güçlü adımların atılması hedeflenmiştir. Bu çalışmada öncelikle hileye ilişkin kavramsal çerçeve sunulmuş, hilenin verdiği zarar boyutu tartışılarak hileye ilişkin sorumluluklar açıklanmıştır. İkinci bölümde ise işletmenin sürekliliği varsayımı ele alınmış ve hilenin işletmenin sürekliliğine etkisi açıklanmıştır.
New technologies to detect electron beam signals
Authors: Alizoti Alion
Published: December 2022

Electricity and electronic devices are playing an overwhelming role in human society. As physical studies are extending the applications of electric currents in metals, electrolyte liquids, gases, vacuum, semiconductors, or superconductors, this paper focuses on the electronic current beam in the vacuum. To this aim, experiments with cathode ray tubes and cathode ray balloons are conducted in our physics lab classes. Therefore, important observations and measurements are accomplished, concerning several physical qualities and quantities. As the electron beam is being visibly observed, electric signals are detected from the beamed target. The observed qualities are assembled and listed, whilst data from the measured quantities are displayed using table and graph plotting.
The utility of ETCO2 value in predicting the progress of the disease and mortality risk in hospitalized patients with COVID-19 pneumonia
Authors: AKYOL Pınar Yeşim , ACAR Hüseyin , KARAALİ Rezan , BORA Ejder Saylav , TOPAL Fatih
Published: December 2022

Aim: End-tidal CO2 (ETCO2) levels are reflective of the ventilatory and metabolic/perfusion status of a patient, regardless of his/her SpO2 values. This study aimed to investigate the utility of ETCO2values in predicting the need for intubation, ICU admission, and mortality in hospitalized patients with COVID-19 pneumonia.

Material and Method: A total of 108 hospitalized patients with COVID-19 pneumonia were included. Data on respiratory parameters (oxygen saturation, ETCO2, and respiratory rate [RR]- with and without O2 [w/wo O2]) and laboratory parameters were recorded.

Results: The need forintensive care unit(ICU) admission was associated with significantly higher ETCO2 values (wO2:27.9 (4.6) vs. 18.6(8.4), p=0.040; woO2: 30.1(4.9) vs. 23.8(6.9), p=0.040). Mortality was associated with higher likelihood of higher RR (wO2:32.4(5.8) vs. 24.6(6.8), p=0.002) and lower oxygen saturation (wO2:92.9(3.8) vs. 95.5(4.2), p=0.025; woO2:87.1(5.7) vs. 91.8(6.6), p=0.013). Presence vs. lack of intubation need was associated with significantly increased likelihood of saturation (wO2:93.1(5.3) vs. 95.9(3.8), p=0.013; woO2:87.6(8.3) vs. 92.3(5.9), p=0.007). Hospital discharge vs. ICU stay was associated with significantly higher ETCO2 values (wO2:27.9 (4.6) vs. 18.6(8.4), p=0.040; woO2: 30.1(4.9) vs. 23.8(6.9), p=0.040)

Conclusion: Our findings revealed the association of decreased ETCO2 (w/wo O2) values with a lower likelihood of hospital discharge and increased likelihood of ICU transfer. Low oxygen saturation levels related the increased risk of both intubation need and mortality in hospitalized COVID-19 patients.
İmmünglobülin G4 ilişkili hastalıkta nüksü etkileyen faktörler: retrospektif bir analiz
Authors: AYDIN TUFAN Müge , KAŞKARİ Derya
Published: December 2022

Amaç: Bu çalışmada immünglobülin G4 ilişkili hastalıkta (IgG4-İH) klinik tutulum özelliklerinin, nüks oranlarının ve nüks ile ilişkili faktörlerin belirlenmesi amaçlanmıştır.

Gereç ve Yöntem: Çalışmamıza IgG4-İH tanısıyla 36 hasta dahil edildi. Bu hastaların demografik, klinik, laboratuvar, radyolojik bulguları, steroid, immünsüpresif tedavi rejimleri ve nüks oranları retrospektif olarak kaydedildi.

Bulgular: Hastaların %36’sı kadındı ve ortalama yaş 58,5±13,2 yıldı. Remisyon oranı %56, nüks oranı ise %19 olarak tespit edildi. İlk tanı anında pankreatit ve retroperitoneal fibrozisi olan hastalarda nüks oranı daha yüksekti (p=0.001). Tek değişkenli analize göre, nüks ile ilişkili bulunan faktörler şu şekildeydi: Hastalık süresi (p=0.001), alerji öyküsü (p=0.018), sigara kullanımı (p=0.027), eozinofili (p=0.001), total IgE (p=0.005) ve kreatinin yüksekliği (p=0.001). Çok değişkenli analizde ise hastalık süresi (Odds oranı (OO) [%95 güven aralığı (GA)]=1.1. [1.01-1.20]; p=0.016) nüks ile ilişkili bağımsız risk faktörü olarak bulundu.

Sonuç: IgG4-İH’li hastalıkta nüks riski, tanı anında pankreas ve retroperitoneal tutulumu olması, alerji öyküsü, sigara kullanımı, eozinofili, total IgE ve kreatinin yüksekliği ile ilişkiliydi. Bu risk faktörlerini taşıyan hastalarda kombine immünsüpresif tedavilerin tercihi ve steroid dozunun kontrollü azaltılması nüksü engellemekte yararlı olabilir.
Radyoterapi uygulanan meme kanserli hastalarda pandemi etkileri
Authors: CEYLANER BIÇAKÇI Beyhan , TEPETAM Hüseyin , GEDİK Duygu , YÜKSEL İrem , ÇOLAKOĞLU Melek , KARABULUT GUL Sule
Published: December 2022

Amaç: Pandemide kanser hastalarının immünsupresif olmaları nedeniyle COVID-19 enfeksiyonuna yakalanma riskinin arttığını ve enfeksiyona bağlı mortalite oranlarının genel popülasyondan daha yüksek olduğunu biliyoruz. Çalışmamızda meme kanseri nedeniyle radyoterapi yapılan hastalarda pandemi etkilerini gözlemlemek, COVID-19 enfeksiyonunu ağır geçirmelerini etkileyen faktörleri analiz etmek amaçlanmıştır.

Gereç ve Yöntem: Çalışmada 01/05/2019-31/12/21 tarihleri arasında tedavi uyguladığımız ve takipteki 122 hasta, onamları alınarak tarafımızca oluşturulan 20 soruluk bir form ile poliklinik kontrolleri sırasında değerlendirildi.

Bulgular: Medyan yaş 50 (aralık 25-84) olup, 62 (%50,8) hasta COVID-19 hastalığını geçirmişti. Hastaların tamamında halsizlik yorgunluk görülmüştü. Hastaların %86’sı aşı yaptırmıştı. %63,1’i önlem için maske kullanmaktaydı. Vitamin kullanımı oranı %21,3’tü. Hastalığı ağır geçirenlerin hiçbiri vitamin kullanmamıştı (p:0,61). Erken evre hastalarda ileri evre hastalara göre vitamin kullanımı daha azdı (p:0,005). Yaş, performans, evre, hastalığı tedavi öncesi veya sonrasında geçirmiş olmak, aşının yapılış zamanı hastalığın ağır geçirilmesi üzerinde istatistiksel olarak anlamlı bulunmamıştır.

Sonuç: Onkoloji hastalarının radyoterapi sürecinde COVID-19 enfeksiyonundan korunmada aşı, maske ve mesafenin en etkili yöntemler olduğu görülmüştür. Vitamin kullanımı ve kullanılan vitamin türünün COVID-19 enfeksiyonunun şiddetine etkisini değerlendirebilmek için daha fazla hasta sayısına ihtiyaç vardır.
End-of-life care in pediatric palliative care
Authors: ŞAHİN Şanlıay , ÖZTEK ÇELEBİ Fatma Zehra , AYAR Ganime
Published: December 2022

The problem of EOL care of a child is very important because the recovery of a family from grief over a child’s death depends on that manner. For improving the quality of this specific care, it would be useful to assess the life expectancy/survival of congenital anomalies, life-threatening diseases, conditions that may shorten a child’s life, and the outcomes of palliative care units regarding mortality. Besides, there is an urgent need for more data on what families define as ‘good death’ and how to cope with the loss. Not only caregivers but also siblings, grandparents, relatives, and healthcare professionals are impacted by a child’s death and their needs must be explored. Pediatric palliative care staff in low/middle-income countries need educational assistance for skills of multidisciplinary training about end-of-life care to improve appropriate care for dying children and their families. It is important to provide sensitive and empathetic end-of-life care to children in a family-centered manner helping them to find comfort, meaning, and support while enhancing the quality of a child’s life and death. Many attending physicians felt inexperienced when communicating with dying patients and their families while discussing the transition to palliative care and resuscitation status. Also, the good death of a child is an emerging concept in this research domain to improve end-of-life care for dying children and their families. The goal of this review was to provide pediatric healthcare professionals and physicians with an overview of palliative care regarding end-of-life issues.
Neuroprotective effect of methanol extract of Capparis spinosa L. fruits in an in-vitro experimental model of Parkinson’s disease
Authors: SEZEN Selma , YESİLYURT Fatma , ÖZKARACA Mustafa , BAYRAM Cemil , ALAYLAR Burak , GÜLLÜCE Medine , HACIMÜFTÜOĞLU Ahmet
Published: December 2022

Aim: Parkinson’s disease (PD) is the second most widespread neurodegenerative disease. This study, it was aimed to investigate the effect of methanol extract obtained from Capparis spinosa L. fruits, which are known to have important bioactive components, on in-vitro experimental PD model.

Material and Method: After collecting Capparis spinosa L. fruits from Alanya/Antalya, methanol extract was prepared by drying and grinding. SH-SY5Y cells grown in flasks were transferred to 96 well plates and were incubated until 80% cell density was reached. Different doses of methanol extract were applied to the cells 30 minutes before the PD model was formed. For the PD model, SH-SY5Y cells were exposed to 200 µM 6-OHDA for 24 hours. MTT analysis was performed to assess the viability of SH-SY5Y cells at the end of the 24-hour period. TOS, TAC, and IL-17A levels in the cell medium were determined using the ELISA method. Expression of TNFα and α-synuclein was defined using the immunohistochemical method.

Results: Cell viability was found to be higher in all treatment groups than in the 6-OHDA group. Moderate levels of TNFα and α-synuclein positivity were observed in the 1500 µg/ml methanol extract group. It was determined that TOS and TAC levels change depending on the dose. It has been determined that the level of IL-17A decreases at low doses. Statistical significance was found between the groups.

Conclusion: When the findings were examined, it was determined that the methanol extract obtained from Capparis spinosa L. fruits reduced oxidative stress and IL-17A levels at low doses and provided a neuroprotective effect by increasing the antioxidant capacity.
Exploring clinical and laboratory findings and treatment outcomes in pregnant inpatients with COVID-19: a single-center experience
Authors: ÖZSOY Metin , ERDİNÇ Şebnem , CESUR Salih , TUNCER ERTEM Gunay , ATAMAN HATİPOGLU Cigdem , KINIKLI Sami
Published: December 2022

Aim: The literature seems to miss the clinical course of COVID-19 infection among the pregnant and its effects on the fetus. The present study aimed to evaluate a total of 21 pregnant inpatients in Ankara Training and Research Hospital with the diagnosis of COVID-19 in terms of symptoms, physical examination findings, laboratory findings, treatment results, and complications. Material and Method: A total of 21 pregnant patients diagnosed with COVID-19 by reverse transcriptase polymerase chain reaction (RT-PCR) in Ankara Training and Research Hospital between 22.04.2020 and 27.09.2021 were included in the study. The clinical symptoms, physical examination findings, laboratory findings, and treatment outcomes of the patients, and the health status of the pregnant and newborn were retrospectively evaluated. Results: Of the 21 pregnant patients, 10 were Turkish citizens, and 11 were foreign nationals. The patients were aged 20-41 years with a mean age of 28.76 years. All patients were unvaccinated. Considering underlying diseases among the patients, it was found that one patient had hypertension, and one patient had thyroid disease. In order of frequency, the symptoms in the patients were cough (n =10), fatigue (n=8), sore throat (n=6), dyspnea (n=5), fever (n=3), myalgia (n=3), joint pain (n=1), and diarrhea (n=1). Physical examinations of the patients yielded a fever of 37.4 °C above in 3 patients and rales in one patient. Although one patient with COVID-19 pneumonia was followed up in the intensive care unit, all were discharged upon recovery. Chloroquine tablets were started in 6 patients, a combination of ritonavir (50 mg) and lopinavir (200 mg) in 4 patients, and favipiravir in one patient. Cesarean section was performed in 9 patients, while 12 patients gave normal delivery. Conclusion: Overall, the clinical course of COVID-19 infection in the pregnant followed up in this study was mild, and all newborns were healthy except for one. It is thought that close follow-ups for the pregnant are needed to minimize complications that may develop in them and their fetuses due to COVID-19 infection. Finally, the COVID-19 vaccine seems to be a must for the pregnant to prevent all possible COVID-related complications.
Relationship between periodontal disease and vitamin D
Authors: AYDOĞAN Tolga , HENDEK Meltem , OLGUN Ebru
Published: December 2022

Vitamin D is a hormone synthesized by human skin cells or consumed through diet with immunomodulatory, anti-inflammatory, and antiproliferative effects. Vitamin D deficiency may increase the risk of periodontal disease by causing decreased bone mineral density, osteoporosis, progression of periodontal diseases, and resorption of the jawbone. In addition, vitamin D is important for bone metabolism, alveolar bone resorption, and the prevention of tooth loss. It increases the antibacterial defense of gingival epithelial cells, reduces gingival inflammation, accelerates postoperative wound healing after periodontal surgery, and is a key supplement functioning as a prophylaxis in periodontology. The present review study aims to highlight the role of vitamin D in periodontal disease.
Otizm Spektrum Bozukluğu Tanılı Çocuk ve Ergenlerde Damgalanma
Authors: Şahin Volkan , Engin Özyurt Gonca
Published: December 2022

Otizm spektrum bozukluğu toplumsal iletişim ve etkileşimde eksikliklerin görüldüğü kısıtlı-yineleyici davranışlar ile karakterize nörogelişimsel bir bozukluktur. Her geçen yıl otizm tanısı alan çocuk sayısının artması göz önüne alındığında bu çocukların bakıcıları, öğretmenleri ve yakınları ile beraber otizmle ilgili kişilerin sayısı toplumun önemli bir kısmını oluşturmaktadır. İnsanların otizm hakkında az bilgiye sahip olmaları ve farkındalıklarının az olması bu çocukların damgalanmalarına dolayısıyla ruhsal açıdan olumsuz etkilenmelerine sebep olabilmektedir. Otizm tanılı çocuk ve ergenlerin farklı iletişim tarzları, tekrarlayıcı hareketleri damgalanmalarına sebep olan önemli faktörlerden bazılarıdır. Otizm spektrum bozukluğu tanısı olan çocuk ve ergenlerin erken yaşta fark edilmesi ve uygun müdahalelerin yapılması topluma uyum sağlamaları açısından büyük önem arz etmektedir. Bu derlemede, son çalışmalar ışığında Otizm tanılı çocuk ve ergenlerde damgalanma konusunun tüm yönleriyle ele alınması ve bu sayede farkındalığın sağlanarak ne tür müdahalelerin yapılabileceği konusunda yol gösterici olunması amaçlanmıştır.
Penaksiran Parameter Distribusi Weibull Menggunakan Algoritma Genetika dan Particle Swarm Optimization
Authors: Nufus Sarah Ayatun , Sutarman Sutarman
Published: December 2022

This study aims toestimate and compare the results of the estimated parameters of the Weibull distributionusing the Genetic Algorithm (GA) and Particle Swarm Optimization (PSO). The Weibull distribution used is a two-parameter Weibull distribution and a three-parameterWeibull distribution. In the GA Algorithm, there are evolution operators such as crossover and mutation. Meanwhile, in PSO algorithm doesn’t. The evolution operators that can optimize complex problems and a very wide search space Evaluation of the two method is carried out by observing the difference in the resulting fitness values.Based on the simulation data from the estimator obtained using the R program, it is found that the two-parameter Weibull distribution parameter and a three-parameterWeibull distribution using a AG algorithm are both used in this distribution. This is supported by the small difference in the fitness value of the GA algorithm obtained compared to the PSO algorithm. The sample space also affects the difference in fitness. The large the sample space, the greater the fitness.
Kajian Prioritas Pengembangan Daerah Wisata Pantai Kecamatan Teluk Mengkudu Menggunakan Metode Analitycal Hierarchy Process
Authors: Manurung Nardi , Nababan Esther Sorta Mauli
Published: December 2022

Analytical Hierarchy Process(AHP) merupakan suatu pemecahan permasalahan yang kompleks dalam suatu struktur multilevel, dimana level pertama adalah tujuan,  level kedua adalah level faktor yang terdiri dari  kriteria dan subkriteria, dan  level terakhir yaitu  alternatif. Langkah awal dari metode ini adalah membuat struktur hierarki dari permasalahan yang akan diteliti. Kemudian dilanjut dengan menyusun matriks perbandingan berpasangan yang selanjutnya akan menghasilkan vektor eigen dan nilai eigen maksimum. Pada proses penentuan faktor pembobotan hierarki maupun faktor evaluasi, harus dilakukan uji konsistensi yaitu CR ≤ 0,1. Skripsi ini bertujuan untuk pengambilan keputusan dalam memilih prioritas pantai yang dapat dijadikan wisata unggulan didaerah tersebut. Hasil dari penelitian terhadap permasalahan diatas dengan menggunakan metode AHP dapat disimpulkan bahwa kriteria yang paling penting dalam proses rencana pengembangan daerah wisata pantai adalah kriteria kuliner dengan bobot 0,25 atau 25%, yang kedua kriteria fasilitas dengan bobot 0,24 atau 24% , ketiga keindahan dan kebersihan dengan bobot kriteria 0,21 atau 21%, yang keempat kriteria akses jalan dengan bobot 0,17 atau 17%, selanjutnya yang terakhir adalah kriteria pelayanan dengan bobot 0,13 atau 13%. Dan pantai yang menjadi prioritas pengembangan adalah pantai sialang buah dengan persentasi 23% , peringkat kedua yaitu pantai mutiara indah dengan persentase 22%, peringkat ketiga pantai sentang 21%, peringkat keempat pantai bogak indah 18%, dan peringkat terakhir pantai taluh dengan persentase 15%.

 

Kata kunci:Metode Analytical Hierarchy Process (AHP), Uji Konsiteni,Vector Eigen.
Model Goal Programming Dalam Mengoptimalkan Jumlah Produksi Olahan Kedelai
Authors: Simanjuntak Naomi Martina , Nasution Putri Khairiah
Published: December 2022

Perencanaan produksi sangat penting dalam manajemen perusahaan. Penyusunan perencanaan produksi harus mempertimbangkan optimalsasi produksi dengan biaya yang minimum. CV. Mawar Siantar merupakan perusahaan pabrik yang bergerak di bidang produksi olahan kedelai. CV. Mawar Siantar mempertimbangkan biaya yang dikeluarkan selama proses manufaktur untuk memaksimalkan keuntungan. Dalam penelitian ini, pemecahan masalah dicapai melalui penggunaan metode goal programming, tidak seperti pemrograman linier, metode ini dapat menyelesaikan banyak masalah. Model Goal Programming yang dipakai adalah model dengan prioritas tujuan. Hasil dari penelitian ini diperoleh solusi yang optimal yaitu tercapainya target volume produksi, biaya produksi tidak melebihi batas target yaitu sebesar Rp. 391.532.301 dan tercapainya target keuntungan yang telah ditetapkan yaitu sebesar Rp. 366.986.784 selama setahun.
Analisis Regresi Data Panel Dengan Pendekatan Common Effect Model (CEM), Fixed Effect Model (FEM) dan Random Effect Model (REM) (Studi Kasus : IPM Sumatera Utara Periode 2014 – 2020)
Authors: Hutagalung Ide Prasanti , Darnius Open
Published: December 2022

Analisis regresi data panel merupakan perpaduan diantara informasi cross section serta time series. Pemanfaatan data panel dapat memaknai dua macam data, yaitu data antar unit dan antar waktu. IPM merupakan penanda yang terpenting adalah menetapkan hasil pada usaha menciptakan hakikat kehidupan manusia, IPM pun mampu menetapkan posisi dan tingkat kemajuan sebuah negara. Studi ini berencana untuk memutuskan model regresi data panel terbaik dan elemen-elemen yang pada dasarnya mempengaruhi IPM di Sumatera Utara. Dalam regresi data panel, ada tiga model penilaian, khususnya CEM, FEM dan REM. Strategi CEM merupakan teknik yang mengharapkan jika intercept dan slope setiap subjek dan setiap kali adalah sesuatu yang serupa, teknik FEM menerima bahwa blok berbeda di antara subjek dan kemiringan adalah sesuatu yang sangat mirip di antara subjek, sedangkan strategi REM menerima bahwa faktor pengganggu mempunyai korelasi antar waktu dan antar subjek. Dari analisis yang telah dilakukan, model regresi data panel terbaik adalah dengan menggunakan Common Effect Model (CEM). Angka harapan hidup, Harapan Lama Sekolah, Rata-rata Lama Sekolah, konsumsi per kapita, dan Persentase penduduk miskin mempengaruhi IPM di Sumatera Utara sebesar 92,71% dan model kondisi penilaian sebagai berikut:
Fungsi Pembangkit Momen dari Distribusi Probabilitas Diskrit
Authors: Sitopu Joni Wilson , Siswadi Siswadi
Published: December 2022

Distribusi jumlah dari dua atau lebih variabel acak. Sementara itu, studi tentang distribusi selisih antara dua variabel acak masih jarang dilakukan, terutama pada variabel acak diskrit. Dari sekian banyak literatur atau buku yang membahas tentang momen faktorial ke-k suatu pendistribusian, masih dalam lingkup yang sangat terbatas, kebanyakan hanya terbatas pada momen pertama dan kedua. Jadi pada artikel ini penulis mengkaji sampai dengan momen faktorial ke-k dari distribusi probabilitas diskrit. Artikel ini berfokus pada perumusan model distribusi probabilitas dan fungsi pembangkit momen variabel acak diskrit, yaitu yang mengaitkan suatu bilangan real pada setiap unsur dalam ruang sampel S yang assosiatif pada percobaan acak.  suatu percobaan (trial) dilakukan secara berulang-ulang sehingga menghasilkan sebanyak n percobaan, misalnya munculnya suatu kejadian (event) adalah sukses dan tidak munculnya suatu kejadian tersebut adalah gagal, Metode yang digunakan untuk menentukan distribusi adalah metode yang dapat untuk menyelesaikan masalah. Karakteristik distribusi diturunkan melalui sifat-sifat momen faktorial ke-k. Berdasarkan hasil dari pembahasan diperoleh model distribusi probabilitas dan fungsi pembangkit momen variabel acak diskrit.
Pengaruh Model Pembelajaran Anchored Instruction Terhadap Kemampuan Pemahaman Konsep Matematik Siswa Kelas XI SMA Al-Maksum Cinta Rakyat
Authors: Maharani Israq , Saragih Risna Mira Bella , Wahyuni Dwi
Published: December 2022

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pembelajaran anchored instruction terhadap kemampuan pemahaman konsep matematika siswa. Desain yang digunakan dalam penelitian ini adalah pretest postest kontrol grup design, dimana terdapat dua kelompok yang dipilih secara random untuk mengetahui pengaruh pembelajaran terhadap kemampuan pemahaman konsep matematik siswa. hasil penelitian menunjukkan bahwa rata-rata kelas eksperimen sebesar 83,7 dan kelas kontrol 75,3. untuk rata-rata postest kelas eksperimen sebesar 90,3 dan kelas kontrol sebesar 83,7. dalam uji hipotesis analisis data, diperoleh thitung 7,815 artinya ada pengaruh model pembelajaran anchored instruction terhadap kemampuan pemahaman konsep matematik siswa.
A generalized Data-Driven Modelling for COVID-19 Pandemic Outbreak: Jordan case study
Authors: Surakhi Ola M. , Salameh Walid , Abu Alhaol Ibrahim , Alkhanafseh Mohammed , Fung Pak Lun , Hussein Tareq
Published: December 2022

The explosion of the COVID-19 pandemic shows the limitations of the existing healthcare system in handling health emergencies. Innovative technologies like artificial intelligence and mathematical modelling can play an essential role in effective planning operations for fighting coronavirus pandemic. In this paper, a comparison between the mathematical model performance and three data-driven models (Feed-forward neural network, Stacked LSTM and Bidirectional LSTM) was performed. These methods (data-driven methods) are applied to model the percentage of positive cases out of the total qPCR tests in Jordan to provide more insight on the appropriate model that can be utilized for COVID-19 disease-spreading analysis. The performance metrics were: mean absolute error (MAE), mean square error (MSE) and coefficient of determination (R2). Our findings show that both mathematical and data-driven models can assess disease-spreading research. However, with the appearance of the new virus variant, Omicron, the mathematical model failed to forecast the pandemic while data-driven approaches are robust and successfully captured the sudden change in the number of positive cases in Jordan. However, much work is still needed to capture more factors in the modelling process and provide a reliable solution for stopping this pandemic.
Yassıçemen Savaşına Giden Süreçte Alâeddin Keykubad ile Celâleddin Harzemşah Arasındaki Diplomatik Münasebetler, Elçiler ve Mektuplar
Authors: Demirci Mustafa
Published: December 2022

Harzemşahlar'ın Moğollara karşı topraklarını kaybetmesinden sonra Cealeddin Harizmşah'ın Azerbaycan'a geldiği 1225-1230 yılları arasındaki beş yıllık dönem, 13. yüzyıl tarihinin en önemli hadiselerinden biridir. Böylece Celaleddin Harizmşah, Selçuklular ve Eyyubiler ile komşu oldu. İlk diplomatik temaslar 1225'te başladı ve dostane ilişkiler 1229'a kadar devam etti. 1229 tarihinde bir anda ilişkiler bozuldu. Ahlat, Erzurum ve Amid-Mardin emirlerinin tahriki ile Eyyubiler, Harizmşahlar ve Selçuklular, karşı karşıya geldiler. Bu nedenle aralarına birçok elçi gidip-geldi ve mektuplar yazıldı. Özellikle Erzurum Meliki Rükneddin Cihanşah'ın Harzemşah ile ittifakı ve Ahlat kuşatması esnasında Harizmşahların masum insanlara yaptıkları kötü muameleler, Alaeddin Keykubat'ın tüm güvenini sarsmıştır. Aralarındaki diplomatik mübadeleler ve görüşmeler yetersiz kaldı. Sonunda Alaeddin Keykubat savaş için Eyyubilerle ittifak kurarak yeni bir cephe oluşturdu. Onlara karşı Harzemşahlar ise Erzurum Meliki ve diğer küçük emirlerle bir cephe oluşturarak savaşa giden süreci başlattılar. Bu makale, Yassıçemen savaşından önce, bu savaşın nedenleri, savaşa yol açan süreçler ve olaylar, elçiler ve mektuplara esas alarak çağdaş kaynakları temel alır. Sonuç olarak Yassıçemen Savaşı kısa vadede kazanılacak bir savaştı ve savaştan on yıl sonra Moğollar tüm savaşan tarafların topraklarını ele geçirdi ve seksen yıl sürecek Moğol egemenliğine girdi.
The Agricultural Sector in the Republic of Kazakhstan: Analysis of the State, Problems and Ways of Solution
Authors: Suieubayeva Saltanat , Denissova Oksana , Kabdulsharipova Aliya , Idikut Ozpenсe Aylin
Published: December 2022

Relevance of the topic – one of the main objectives of the economic security of the country is to create competitive industries to meet the needs of the population and replace imports of socially essential goods. Kazakhstan's consumer market still retains a high share of imported products, so for the sustainable development of Kazakhstan, it is necessary to form and activate potential economic growth points, primarily in the agricultural and industrial sectors. The purpose is to study the current state of the agricultural industry of the Republic of Kazakhstan and to identify trends in its development. The methods include the systematization of information from the analyzed literature sources: analysis, synthesis, structuring, and traditional ways of economic analysis, such as comparison and details. Results – the state of the agricultural industry in the Republic of Kazakhstan was analyzed; a comparison of indicators of agricultural production output of the Commonwealth countries was carried out; key areas affecting the increase in the gross domestic product of the country by increasing the production of agricultural products were identified. It is recommended to build a model for assessing the state of problems to improve the level of development of the agro-industrial complex.
Imputed Insurance in the Republic of Kazakhstan: Problems, Solutions and Development Prospects
Authors: Kaderova Natalia , Dosmanbetova Manshuk , Leshchinskaya Sofia
Published: December 2022

The global insurance market, including the market of Kazakhstan, is in constant development and change due to instability in geopolitics, global and national economy. It is worth noting that, despite the growth, the development of the insurance market in Kazakhstan lags behind developed countries. Kazakhstan needs to increase the percentage of the contribution of insurance assets to the GDP structure.  This article discusses the main problems hindering the development of the insurance market and, in particular, the development of imputed insurance in Kazakhstan, provides a number of recommendations to eliminate these problems and proposals for further development of the insurance market.
Implementation Program of the School Operational Assistance: A Case Study in Berau District
Authors: Sugesti Dewi , Asri Syachrumsyah , Sudirah Sudirah
Published: December 2022

School Operational Assistance (SOA) is a government program to improve the quality and quality of learning in state schools. Yet, SOA reporting was colored by delays by various schools. Reporting must be under regional financial administration. On the other hand, schools are required to make reports according to the format from the Ministry of Education and Culture of the Republic of Indonesia. Through this paper, the author analyzes the implementation of the SOA policy at the elementary (SD) and junior high school (SMP) levels. Too, we also analyze the factors that support and hinder the implementation of the policy in public schools in Berau District. This study uses a descriptive method with a case-qualitative study. Referring to absorption capacity, effectiveness, accountability, transparency, implementer commitment, goals and targets, as well as analyzing the factors that influence SOA policy, it shows that its actualization in schools located in the city center have "good" absorption and effectiveness, while schools located in far from the city center is categorized as “moderate”. Accountability, transparency, commitment of implementers in general have gone well. Thus, schools that are far from the city center are still not optimal, for example in providing information related to the use of SOA. The goals and objectives of the SOA program have been achieved, but the financing of competency standards in schools is still inadequate. The analysis shows that the lack of appropriateness of this program is triggered by the lack of communication, human resources, bureaucratic structure, and characteristics of the implementer. Therefore, it needs serious attention from implementers, schools, and local governments to find solutions, especially in providing support for increasing competence, especially school principals and treasurers so that this policy can be accounted for in a transparent and accountable manner.
Impact of Covid-19 on Profitability (Case Study on The Health Subsector Listed on Indonesia Stock Exchange)
Authors: Rosita Reta , Wadud Muhammad , PurnamaSari Endah Dewi
Published: December 2022

This study aims to explore the impact of the Covid-19 pandemic on the profitability of health subsector companies listed on the Indonesia Stock Exchange. The aspects analyzed in this study were gross profit margin, net profit margin, return on assets, and return on equity. Samples were selected deploying purposive sampling technique. Data of 9 companies were collected from the investment gallery of the Indonesia Stock Exchange (BEI). This study implemented a series of paired sample t-test to analyze data before and during the Covid-19 pandemic. The results evidenced that there is no significant difference between before and during the Covid-19 pandemic for each aspect of gross profit margin, net profit margin, return on assets, return on equity.
Knowledge about Cryptocurrencies: Consumer Behavior Survey
Authors: Scimone Xenia
Published: December 2022

Although the cryptocurrency market has grown significantly in recent years, few studies have been done on socio-demographic features and not influencing the degree of consumer knowledge about cryptocurrencies. Based on a survey submitted to 774 subjects representative of the Italian population, we find that 89% of Italians know cryptocurrencies and 39% of them have a good or thorough knowledge. The aptitude for knowledge and use of cryptocurrencies is greater for male and well-educated subjects and also increases as the propensity to invest in cryptocurrencies increases. 41% invest or want to invest in cryptocurrencies and the investment is particularly attractive for those who mainly aim at portfolio diversification and obtaining high returns. The findings have important implications for regulators and supervisors who are interested in understanding the social relevance of the phenomenon.