bluuebunny/crossref_metadata_2025 huggingface dataset:
Administrative Penology: Modern Research Prerequisites
Authors:   Head of the Department of State and Legal Disciplines of the Far Eastern Branch of the Russian State University of Justice Professor of the Department of Administrative Law and Administrative Activities of Internal Affairs Agencies of the Far Eastern Law Institute of the Ministry of Internal Affairs of Russia LL.D., Associate Professor, Deryuga Artem N. , Shaklein Sergey N. ,   Junior Scientific Assistant of the Department of Administrative Law and Administrative Activities of Internal Affairs Agencies of the Far Eastern Law Institute of the Ministry of Internal Affairs of Russia
Published: November 2021

Administrative punishment is the most important legal “lever” to reduce the level of administrative tort. Hence, it is important to study the issue of increasing the effectiveness of administrative punishment and the formation of a special scientific directionadministrative Penology, the Central element of the subject of which is administrative punishment and those phenomena, events, facts, States and processes that form the legally fixed type and limits of administrativetort sanctions. The need for a comprehensive study of administrative punishment is associated with obtaining the most effective result, designed for the long term, by analyzing the effectiveness of the existing exclusively legal mechanism for the appointment and execution of administrative punishments and searching for reserves of administrative punishment, using the achievements of legal, sociological and psychological Sciences.
Public Property Authorities
Authors:   Professor of the Department of Administrative Law and Procedure of the Kutafin Moscow State Law University (MSAL) LL.D., Professor, Agapov Andrey B.
Published: November 2021

The content of the powers of possession, use and disposal of public property of the federal government, the President of the Russian Federation, federal executive authorities is investigated. The article considers the prescriptions of the constitutions and charters of the constituent entities of the Russian Federation, which determine the content of the powers to manage public property, while the presence of public (state and municipal), as well as private and intellectual property is postulated directly in the Constitution of the Russian Federation. The constitutional legislation of the constituent entities of the Russian Federation determines the foundations of the legal status of another type of public property, namely the common property of the city of Moscow and the Russian Federation, along with it, the Constitution of the Republic of Sakha (Yakutia) provides for the existence of collective property.
Judicial Protection of Individuals in an Administrative Procedure by Means of Administrative Proceedings
Authors:   Head of the Department of Administrative Law and Procedure named after N.G. Salischeva Chief Research Scientist (Department Head) of the Center for Study of Justice Issues of the Russian State University of Justice LL.D., Professor, Stakhov Aleksandr I.
Published: November 2021

The article highlights and studies judicial protection of individuals and organizations (individuals) in the administrative process as a special way of implementing justice on the appeals of citizens and their associations for the protection of their rights, freedoms, and legitimate interests in the course of Executive (non-judicial) and judicial administrative processes from the perspective of an integrative understanding of the administrative process. Taking into account the direct effect of the norms of the Constitution of the Russian Federation, the legal basis for judicial protection of individuals in administrative proceedings consists of two components: 1) the constitutional basis for; 2) legal grounds. Conducted a comprehensive analysis of the legal norms that constitute the constitutional basis and a legislative basis for judicial protection of individuals in administrative process, in which: justified the constitutional right of individuals to protection in the administrative process through the administrative procedure; is General conclusion that the subject of this judicial protection are contested in courts decisions and actions (inaction) of administrativepublic bodies and officials; the author substantiates the allocation of administrative court cases on the protection of individuals in administrative proceedings, which are divided into separate categories depending on the nature of the legal consequences of disputed decisions, actions (inaction) of administrative and public authorities and officials, as well as the nature of the dispute being resolved. In accordance with art. 72 of the Constitution of the Russian Federation allocated administrative law and administrative procedural decisions and actions challenged in court, in administrative proceedings, is the typology that best reveals the current level of processualists administrative activities public administration, other administrative public authorities and administrative public officials operating in the Russian Federation, allows you to identify priority areas of optimization of administrative proceedings in cases of settlement of administrative law disputes.
The Civil Law Mechanism of Compensation for Property Damage Caused by an Administrative Offense
Authors:   Associate Professor of the Department of Administrative Activities of Internal Affairs Agencies of the Nizhny Novgorod Academy of the Ministry of the Interior of Russia PhD (Law), Kostrova Olga V.
Published: November 2021

Тhe paper analyzes the legal structure of Article 4.7 of the Administrative Code of the Russian Federation. The issues of compensation for property damage in civil proceedings are considered. It is necessary to specify the category of “legal dispute” and legislative changes regulating the procedure for reimbursement of court costs in administrative cases terminated on rehabilitative grounds and property damage as a result of an administrative offense.
Why and How to Use the Body’s Own Stem Cells for Regeneration in Musculoskeletal Disorders: A Primer
Authors: Furia John , Lundeen Mark , Hurd Jason , Pearce David , Alt Christopher , Alt Eckhard , Schmitz Christoph , Maffulli Nicola
Published: November 2021

Background: Recently, the management of musculoskeletal disorders with the patients' own stem cells, isolated from the walls of small blood vessels, which can be found in great numbers in the adipose tissue, has received considerable attention. On the other hand, there are still misconceptions about these adipose-derived regenerative cells (ADRCs) that contain vascular-associated pluripotent stem cells (vaPS cells) in regenerative medicine. Methods: Based on our previous publications on this topic, we have developed a concept to describe the significance of the ADRCs/vaPS cells in the field of orthobiologics as briefly as possible and at the same time as precisely as possible. Results: The ADRCs/vaPS cells belong to the group of orthobiologics that are based on autologous cells. Because the latter can both stimulate a patient’s body's localized self-healing power and provide new cells that can integrate into the host tissue during the healing response when the localized self-healing power is exhausted, this group of orthobiologics appears more advantageous than cell-free orthobiologics and orthobiologics that are based on allogeneic cells. Within the group of orthobiologics that are based on autologous cells, enzymatically isolated, uncultured ADRCs/vaPS cells have several advantages over non-enzymatically isolated cells/microfragmented fat as well as over uncultured bone marrow aspirate concentrate and cultured cells (adipose-derived stem cells, bone marrow-derived mesenchymal stem cells). Conclusions: The use of ADRCs/vaPS cells can be seamlessly integrated into modern orthopedic treatment concepts, which can be understood as the optimization of a process which - albeit less efficiently - also takes place physiologically. Accordingly, this new safe and effective type of treatment is attractive in terms of holistic thinking and personalized medicine.
Metric Dimension in fuzzy(neutrosophic) Graphs-III
Authors: Garrett Henry
Published: November 2021

In this study, the term dimension is introduced on fuzzy(neutrosophic) graphs. The classes of these specific graphs are chosen to obtain some results based on dimension. The types of crisp notions and fuzzy(neutrosophic) notions are used to make sense about the material of this study and the outline of this study uses some new notions which are crisp and fuzzy(neutrosophic).
MRI CNS Atrophy Pattern and the Etiologies of Progressive Ataxias
Authors: Mascalchi Mario
Published: November 2021

MRI shows in-vivo the three archetypal patterns of CNS volume loss underlying progressive ataxias, namely spinal atrophy (SA), cortical cerebellar atrophy (CCA) and olivopontocerebellar atrophy (OPCA). The MRI-based CNS atrophy pattern was reviewed in 128 progressive ataxias. A CNS atrophy pattern was identified in 91 conditions: SA in Freidreich’s ataxia, CCA in 5 acquired and 72 (24 dominant, 47 recessive,1 X-linked) inherited ataxias, OPCA in Multi-System Atrophy and 12 (9 dominant, 2 recessive,1 X-linked) inherited ataxias. The MRI-based CNS atrophy pattern may be useful for genetic assessment, identification of shared cellular targets, and repurposing therapies or enlargement of drugs indications in progressive ataxias.
Eight-Year Retrospective Study of Young Adults in a Diabetes Transition Clinic
Authors: Sritharan Aarooran , Osuagwu Uchechukwu Levi , Ratnaweera Manjula , Simmons David
Published: November 2021

The transition of people from paediatric to adult diabetes services is associated with worsening glycaemia and increased diabetes-related hospitalisation. This study compared the clinical characteristics of those with and without mental health conditions among attenders at a diabetes young adult clinic diabetes before and after changes in service delivery. Retrospective review of 200 people with diabetes attending a Sydney public hospital over eight years corresponding to the period before (2012-2016) and after (2017-2018) restructuring of a clinic for young adults aged 16-25 years. Characteristics of those with and without mental health conditions (depression, anxiety, diabetes related distress, eating disorders), were compared. Among clinic attenders (type 1 diabetes n=184, 83.2%), 40.5% (n=89) had a mental health condition particularly, depression (n=57, 64%), which was higher among Indigenous than non-Indigenous people (5.6% vs 0.8% p=0.031) but similar between diabetes type. Over eight years, those with, compared with those without a mental health condition had higher HbA1c at the last visit (9.4%[79 mmol/mol] vs 8.7% [71 mmol/mol], p=0.027), the proportion with diabetic ketoacidosis (DKA 60.7% vs 42.7%,p=0.009), smoking (38.4 vs 13.6%,p=0.009), retinopathy (9.0 vs 2.3%,p=0.025), multiple DKAs (28.4 vs 16.0%,p=0.031) were significantly higher. Having a mental health condition was associated with 2.02 (95% Confidence intervals 1.1-3.7) fold increased risk of HbA1c ≥ 9.0%[75mmol/mol]. Changes to the clinic were not associated with improvements in mental health condition (39.0% vs 32.4%, p=0.096). In conclusion, we found that mental health conditions, particularly depression, are common in this population and are associated with diabetes complications. Diabetes type and clinic changes did not affect the reported mental health conditions. Additional strategies are required to reduce complication risks among those with mental health conditions. .
Climate Normalized Spatial Patterns of Evapotranspiration Enhance the Evaluation of Hydrological Models
Authors: Koch Julian , Demirel Mehmet Cüneyd , Stisen Simon
Published: November 2021

Spatial pattern-oriented evaluations of distributed hydrological models have contributed towards an improved realism of hydrological simulations. This advancement was supported by the broad range of readily available satellite-based datasets of key hydrological variables, such as evapotranspiration (ET). At larger scale, spatial patterns of ET are often characterized by an underlying climate gradient, and with this study, we argue that gradient dominated patterns may hamper the potential of spatial pattern-oriented evaluation frameworks. We hypothesize that the climate control of spatial patterns of ET overshadows the effect model parameters have on the simulated variability. To solve this limitation, we propose a climate normalization strategy. This is demonstrated for the Senegal River basin as modeling case study, where the dominant north-south precipitation gradient is the main driver of the observed hydrological variability. Two multi-objective calibration experiments investigate the effect of climate normalization. Both calibrations utilize observed discharge (Q) in combination with remote sensing ET data, where one is based on the original ET pattern and the other utilizes the normalized ET pattern. We identify parameter sets that balance the tradeoffs between the two independent observations and find that the calibration using the normalized ET pattern does not compromise the spatial patern performance of the original pattern. However, vice versa, this is not necessarily the case, since the calibration using the original ET pattern showed a poorer performance for the normalized pattern. Both calibrations reached comparable performance of Q. With this study, we identified a general shortcoming of spatial pattern-oriented model evaluations using ET in basins dominated by a climate gradient, but we argue that this also applies to other variables such as, soil moisture or land surface temperature.
Gene Therapy Approach for Treating DeltaF508, G542X and R553X Cystic Fibrosis Mutations Through the Usage Of CRISPR Prime Editing
Authors: Tafa Mira , Karışık Sevim Naz , Aksoy Ece Begüm , Aslan Rüya
Published: November 2021

Cystic Fibrosis is a rare genetic disease that affects the transmission of chloride ions due to mutations in the CFTR (cystic fibrosis transmembrane conductance regulator) gene. Even though there are nearly 2000 mutations identified to be related to the condition, the most common mutation is F508del; deletion of a phenylalanine residue at 508. On the other hand, G542X which is a Class I mutation is also found very commonly and there are no modulator treatments available for it. Furthermore, it was investigated that R553X mutation can as well be corrected simultaneously with G542X mutation. Therefore, the main focus is on designing a gene therapy project that can correct all these three mutations at once by utilizing the prime editing technique via lipid-based delivery. In this way, the mutations can be edited through plasmids that were designed containing 2 pegRNAs and the Cas enzyme. To implement such an approach efficiently, both ex vivo, an animal model, and in vivo steps are to be designed. For the cell line, fibroblasts are selected due to their simplicity and low cost. The animal model of the experiment is determined to be a ferret concerning the high similarity to the human's CFTR protein and finally, the procedure will follow on a direct application in human Cystic Fibrosis patients. The plasmids are thought to be delivered through a cationic liposome that will reach the lungs with the aid of a nebulizer. At the last stage of the experimental procedure, Sanger Sequencing will be done to see if the desired edit within the CFTR has been performed successfully, and Next Generation Sequencing will be executed to see if there has been an off-target mutation in the remainder of the genome. Whereas for detecting the presence and expression of CFTR protein in humans, immunodetection with flow cytometry will be conducted.
Analisis Pengendalian Kualitas Pada Pengolahan Produk Kulit Dengan Metode Statistical Process Control Pada UMKM Paris Leather
Authors: Nuryanto Dimas Ari , Setiafindari Widya
Published: November 2021

Pada proses produksi kulit pada UMKM Paris Leather masih terdapat kecacattan saat proses pewarnaan kulit dan proses pembuatan produk kulit, dimana proses produksi kulit tidak sesuai dengan standar kecacatan produk yang telah ditentukan oleh UMKM Paris Leather. Dari data produksi produk kulit pada bulan Januari s.d Februari 2021 mencapai 933 produk lembaran kulit, 173 produk tas dan 155 produk jaket, masih terdapat produk cacat pada produksi dengan jumlah rata-rata cacat produk kulit lembaran 5 % per hari, produk tas 4 % per hari dan produk jaket 3 % per hari dengan jumlah produk cacat yang terjadi perlu dilakukan usulan perbaikan kualitas untuk mengurangi cacat pada produk kulit, maka dalam meyelesaikan masalah tersebut perlu menganalisis apa saja jenis cacat dominan yang terjadi pada produksi kulit, kemudian mencari penyebab cacat pada produk dan pewarnaan yang terjadi di UMKM Paris Leather. Analisis data dilakukan dengan menggunakan teknik Statistical Quality Control, Check Sheet, Stratifikasi, Peta Kontrol, Diagram Pareto, Diagram Sebab-Akibat, Diagram Pencar, dan Histogram. Hasil dari penelitian ini menunjukan jenis kerusakan yang paling banyak terjadi pada proses produksi kulit adalah cacat jahit tidak rapi sebesar 50 % produk tas, 40 % produk jaket, dan proses perwarnaan kulit cacat lubang sebesar 50 %. Usulan perbaikan sebaiknya dilakukan adalah mengkaji ulang proses pengoperasian mesin, menggunakan check sheet, melaksanakan training, memberlakukan sistem reward and punishment, pengecekan material dan mesin, dan bekerja sesuai SOP.

Kata kunci: Statistical Quality Control1, Produk Kulit2, UMKM Paris Leather3
THE CONCEPT OF COMBUSTION PROCESS ORGANISATION IN A BOXER TWO-STROKE DIESEL ENGINE AT A HIGH LEVEL OF BOOSTING
Authors: Parsadanov I.V. , Lal A.G.
Published: November 2021

Based on the analysis and synthesis of previously performed theoretical and practical studies, the paper proposes a concept of combustion process organization in a boxer two-stroke diesel engine at a high level of boosting. Such diesel engines are produced in Ukraine and are widely used in land, sea and rail transport, as diesel generator plants. The implementation of this concept will ensure the reduction of the thermal stress of the cylinder piston group for these diesel engines, while improving fuel efficiency.

The features of the organization of the working process in a boxer two-stroke diesel engine are briefly considered. The contribution of Ukrainian, Russian and American scientists to the development and improvement of their mixing efficiency is noted.

Following the purpose of the research, which determines the choice of directions for the development and implementation of technical solutions for the simultaneous reduction of fuel consumption and thermal tension of the cylinder-piston group when forcing a boxer two-stroke diesel engine, it is proposed to use the amount of released heat as a criterion for evaluating the quality of combustion.

Based on the results of earlier studies, conceptual foundations for increasing the efficiency of the combustion process of a highly boosted boxer two-stroke diesel engine have been developed, which are directly related to the air supply, fuel supply, the rationale for choosing the shape of the combustion chamber are determined by the amount of heat released during combustion and the nature of its change in the crankshaft rotation angle.
RESEARCH OF THERMAL AND MASS-EXCHANGE PROCESSES IN GAS-LIQUID FILM ABSORBERS IN SURFACE-ACTIVE TECHNOLOGY
Authors: Dzevochko O. , Podustov M. , Dzevochko A.
Published: November 2021

The article states that surfactants have an asymmetrically constructed molecule that contains hydrophilic and hydrophobic groups. The main department of surfactant production is the process of sulfation of organic matter with gaseous sulfur trioxide.

It is shown that the process of sulfation in gas-liquid film absorbers consists of the following stages: the process of mass transfer of sulfur trioxide from the gas stream to the liquid phase; the process of absorption of sulfur trioxide by organic matter with the passage of an exothermic chemical reaction; the process of heat exchange between the liquid phase and the gas stream; the process of heat exchange between the liquid phase and the flow of cooling water.

Studies of heat and mass transfer processes at these stages make it possible to select the necessary equations for the calculation of heat transfer coefficients, heat transfer coefficients and mass transfer coefficient.

It is recommended to calculate the heat transfer coefficient from liquid to gas by the equation when the diffusion and thermal Prandtl numbers are close to unity. The use of the classical equation to calculate the heat transfer coefficient from the liquid phase to the wall of the reaction tube did not give the desired result. Therefore, an equation was used that takes into account the properties of the gas-liquid flow as a whole. It is recommended to calculate the heat transfer coefficient from the reaction pipe wall to the cooling water flow according to the classical Nusselt equation.

Experimental data processing data for calculating the density and dynamic viscosity of the reaction mass along the length of the reactor are presented.

The equation for calculating the mass transfer coefficient was obtained by analyzing 6 equations of different authors who were engaged in the process of sulfation of organic substances. A mathematical description of the sulfation process in a film absorber was developed for analysis. During the development of the mathematical description, the balance equations of mass and heat transfer for the reaction tube were compiled. Based on the results of mathematical modeling, an equation was chosen that includes the tangential stress at the gas-liquid interface.

The results of mathematical modeling were compared with Gutierrez's experimental data and the results of Dabir's mathematical modeling. The obtained results will be used in mathematical modeling of the sulfation process in a film absorber.
THE USE OF NANO AND BIOTECHNOLOGICAL RAW MATERIALS IN THE CREATION OF DRUGS FOR AGRICULTURE
Authors: Krichkovskaya L. , Lysak P. , Dubonosov V. , Gritsayenko Y.
Published: November 2021

The article is devoted to the consideration of the possibility of using fullerene-containing water as part of humic growth-stimulating preparations for agriculture with the addition of yeast production waste. More recently, the problems of the economy and the environment were perceived as opposite. Currently, there is a need for a mutually dependent and mutually beneficial combination of economic and environmental interests, which was the basis for this study. The analysis of the wastewater of the yeast-producing enterprise shows the presence of a large number of chemical and organic substances that pose a certain danger to the environment, but are useful after processing waste for use in agriculture. The largest number of substances is found in waste, after the stage of production of pure culture. The experiment shows that the use of structured water in combination with biologically active waste from the production of bread yeast obtained on the basis of the Saccharomyces cerevisiae strain increases the yield of grain crops. Based on the established fact of a wide and universal spectrum of biological activity of the water-carbon structure of hydrated fullerenes, according to patent and scientific and technical literature, they have not been widely tested as plant growth regulators. We will investigate the interaction of substances with water structured with fullerenes, the effect of surfactants on the formation and stability of emulsified humates with film-forming agents, the adhesive properties of the components, the effect of concentrated yeast fermentation liquid separated after the stage of growing a pure culture of baking yeast, the effect of both a fullerene-like structure – shungite of natural origin and hydrated fullerenes – highly stable finely dispersed aqueous solutions of native fullerenes (have the properties of lyophobic molecular colloidal systems) on grain yield, protection of vegetative plants. The result of the work will be the substantiation of the principles of the methodology for the application of nanostructured substances for use in biotechnologies of multifunctional highly effective drugs for agriculture with biologically active additives.
PENGEMBANGAN SEBUAH PENGAJARAN RESPONSIF BUDAYA (CRT) PADA KELAS DRAMA (SEBUAH KOLABORASI MAHASIWA DALAM PEMENTASAN DRAMA CERITA LOKAL)
Authors: Hambandima Erny Selfina Nggala
Published: November 2021

DEVELOPING A CULTURALLY RESPONSIVE TEACHING (CRT) ON TEACHING DRAMA ( A COLLABORATION ON STUDENTS’ LOCAL STORY DRAMA PERFORM)

                                                                          ESNHAbstract: This study is meant to investigate how lecturer develop a culturally responsive teaching on drama class especially students’ collaborative of local story drama perform. The problem of this research is formulated as how does the lecturer develop CRT on teaching drama? The study was stimulated by the writer’s interest to examine the CRT on a collaboration of 5th semester students’ local story drama performance by understanding the local story through drama teaching whereas nowadays teaching also touch about the local content.  The research subjects are 5th semester students from 3 different classes that the writer collaborate them in a collaboration team.  The writer randomly collaborate the students by means of getting them to adapt, cooperate and create their own acting to be more fearless, creative in front of the stage. A qualitative research was conducted by observing the students’ activity and watching the video documenting students’ performance. From the data result the writer found that the drama class based CRT are the students learn within the context of different culture, students being the center in teaching and learning process, students adjusted the learning with the group members and the teacher being the mediator to succeed the students’ project. The conclusion is the students enrich their knowledge of historical story from different ethnics as well as they authentically know the differences local story among them. The suggestions are the educators should convey the local content in teaching and learning process in class based culturally responsive teaching.

Keywords: Developing, Culturally Responsive Teaching (CRT), Teaching Drama, Collaboration
Internalization of Multicultural-Based Islamic Education: Sunni-Shia Synergy in Banjaran Bangsri Village, Jepara
Authors: Saefudin Ahmad , Munip Abdul , Ulfa Khoirotul Laila
Published: November 2021

This research aims to reveal the role of Sunni-Shia Islamic educational institutions in building multiculturalism in a pluralistic society. So far, the Sunni-Shia relationship has been depicted in a conflictual scheme. The research method was qualitative from the sociology of education perspective. Through in-depth interviews, participatory observation and documentation techniques, this study showed that the atmosphere of peace between Sunni-Shia in Banjaran is reflected in the social works of humanity, organizations and Islamic educational institutions. Multicultural education cannot be separated from the role of formal and non-formal Islamic education institutions such as TPQ Al-Husainiah (Shia), TPQ Ma'arif 17 KH. Muhammad Arif (Sunni) and MI Mabadil Huda (Sunni). The kinship also has a contribution to maintaining Sunni-Shia harmony in Banjaran. Theoretically, this research contributes to the development of multicultural Islamic education models in rural. Practically, it is beneficial for Islamic education institutions in building awareness of multiculturalism and tolerance between religious sects.
Oral and IV Antibiotic Administration After Single-Stage Revision Shoulder Arthroplasty
Authors: Yao Jie J. , Jurgensmeier Kevin , Whitson Anastasia J. , Pottinger Paul S. , Matsen Frederick A. , Hsu Jason E.
Published: November 2021

Background:

Following revision shoulder arthroplasty, postoperative antibiotics are selected before the results of intraoperative cultures become available. We determined infection-free survival, revision-free survival, complications, and patient-reported outcomes for patients selected to receive oral or intravenous (IV) antibiotics after revision arthroplasty.

Methods:

This study included 92 patients who had revision shoulder arthroplasty. IV antibiotics were administered if the surgeon had a high index of suspicion for infection, and oral antibiotics were given if there was a low suspicion. Antibiotic therapy was modified based on intraoperative culture results. Patient-reported outcomes and adverse events were documented at a mean of 4.1 years.

Results:

In selecting antibiotic therapy, surgeons correctly predicted the presence or absence of multiple positive cultures of specimens from the revision surgery in 72% of the 92 cases. Subsequent re-revision surgery was required in 17 (18%) of the patients; 8 of these 17 patients had ≥2 positive cultures at re-revision. Patients who initially received IV antibiotics and those who initially received oral antibiotics had similar revision-free (p = 0.202) and infection-free (p = 0.155) survivorship. Patients requiring a change from oral to IV antibiotics based on positive cultures had similar survivorship compared with those initially treated with IV antibiotics. The IV and oral antibiotic groups had similar postoperative Simple Shoulder Test (SST), American Shoulder and Elbow Surgeons (ASES), and satisfaction scores. Patients receiving IV antibiotics had a higher rate of antibiotic-related adverse events.

Conclusions:

Post-revision antibiotic therapy was associated with an infection-free survival rate of 91% at a mean of >4 years of follow-up. Infection-free survival, revision-free survival, and patient-reported outcomes were similar in high-risk patients placed on IV antibiotics and low-risk patients placed on oral antibiotics. Further study is needed to define the indications for IV or oral antibiotics after revision arthroplasty.

Level of Evidence:

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Media pembelajaran video produk kreatif dalam pembuatan softcase laptop produk kreatif di era pandemi covid-19
Authors: Astuti Yayuk  Dwi , Haryanti Nik
Published: November 2021

ABSTRAK: Penggunaan media dalam proses pembelajaran dapat membangkitkan keinginan-keinginan dan minat yang baru, membangkitkan motivasi, dan rangsangan kegiatan belajar, bahkan membawa pengaruh-pengaruh psikologis terhadap siswa. Berkenaan dengan penyebaran Coronavirus Disease (covid 19) yang semakin meningkat maka kesehatan seluruh warga sekolah menjadi pertimbangan utama dalam pelaksanaan pembelajaran khususnya mengenai media pembelajaran secara daring. Dengan demikian, siswa harus punya pendamping belajar, hal ini terjadi karena nilai KKM siswa di sekolah minim. Terutama masalah pelajaran kewirausahaan siswa sebagian belum ada keinginan untuk berwirausaha. Dengan wujud media video tutorial ini dapat tumbuh imajinasi kreatifitas dari setiap siswa terkait wirausaha produk kreatif.  Salah satu media yang dapat dimanfaatkan peserta didik untuk belajar mandiri adalah menggunakan media video produk kreatif wadah laptop. Penggunaan video   sebagai media belajar dapat membuat peran guru ke arah yang lebih positif dan produktif. Guru dapat berbagi peran dengan media sehingga memiliki banyak waktu untuk memberi perhatian pada aspek-aspek edukatif lainnya, seperti membantu kesulitan belajar siswa, pembentukan kepribadian, memotivasi belajar, dan lain-lain.
Pengaruh self efficacy, persepsi profesi guru dan lingkungan keluarga terhadap minat menjadi guru akuntansi pada mahasiswa S1 pendidikan akuntansi UNESA
Authors: Ayu Prastiani Devy , Listiadi Agung
Published: November 2021

The research conducted has the title Influence of Self Efficacy, Perception of Teacher Profession And Family Environment On Interest in Becoming An Accounting Teacher In Undergraduate Students of Accounting Education UNESA aims to know if there is an influence between self efficacy, perception of teacher profession and environment in the family for interest in accounting teachers. Accounting Education Students faculty of Economics and Business Surabaya State University is made as a population with a total of 317 students. Where the sample was selected as many as 177 students. The method chosen for sample collection in this research is proportional random sampling technique. Data collection method in the form of questionnaires distributed to accounting education students. Researchers used multiple linear regression analysis as the analysis method for this study. From the research obtained results simultaneously the presence of positive and significant influences between self efficacy, perception of the teacher's profession and the family environment to the interest of becoming a teacher.
MODEL INOVASI PEMBELAJARAN MAHASISWA BERKEBUTUHAN KHUSUS (MBK) BERBASIS VIDEO BERSUBTITLE
Authors: Faisal Estu Yulianto  , Bambang Kurnadi  , Hasan Basri  , Ukthi Raudhatul Jannah  , Zayyadi Moh
Published: November 2021

Penelitian ini bertujuan untuk mengembangkan model pembelajaran secara daring yang ramah dan cocok bagi mahasiswa sesuai dengan kebutuhan khusus. Pengembangan model berbasis video yang digunakan dalam penelitian ini adalah model Desain Pembelajaran ADDIE (Analysis-Design-Develop-Implement-Evaluate). desain produk ini diantaranya: (1) RPS; (2) Materi ajar; (3) Video Pembelajaran; dan (4) Evaluasi Pembelajaran.  Teknik pengumpulan data yang dilakukan pada penelitian ini dalam bentuk angket dan dokumentasi. Teknik analisis data yang digunakan dalam penelitian ini yaitu skala pengukuran menggunakan skala Likert. Hasil penelitian ini adalah karakteristik model pembelajaran pada kegiatan ini adalah penggunaan media pembelajaran berupa video pembelajaran bersubtitle yang digunakan untuk mempermudah pemahaman konsep kalkulus pada mahasiswa normal dan mahasiswa berkebutuhan khusus. Secara umum pembelajaran yang diberikan dapat diterima dengan baik oleh semua mahasiswa, khususnya mahasiswa berkebutuhan khusus dengan gangguan pendengaran.
Identification of a lncRNA-Related Competing Endogenous RNA Network in Recurrent Implantation Failure
Authors: Huang Kai , Shi Ying , Chen Gezi
Published: November 2021

Background
Impaired endometrial receptivity is supposed to be a major element leading to recurrent implantation failure (RIF). Numerous studies have identified that the lncRNAs-miRNAs-mRNAs regulation network functions in the generation of receptive uterus. Long non-coding RNAs could act as competing endogenous RNAs in the pathogenesis of RIF. However, our understanding of the underlying mechanism is still limited.
Results
Based on the RNA-Seq results, 617 DEmRNAs, 69 DElncRNAs and 107 DEmiRNAs were identified in the RIF group compared with the control group. To investigate the role of lncRNAs in RIF, we constructed a lncRNA related ceRNA network. A total of 3 lncRNAs, 8 miRNAs and 69 genes were identified. Above all, our study obtained 120 lncRNAs-miRNAs-mRNAs relationships in the ceRNA network. Among three hub lncRNAs, PART1 and PWRN1 were upregulated whereas PGM5P3-AS1 was downregulated in RIF endometrium. Meanwhile, three down-regulated miRNAs (hsa-miR-1207-5p, hsa-miR-134-5p, hsa-miR-1225-5p) and five up-regulated miRNAs (hsa-miR-30c-5p, hsa-miR-30b-5p, hsa-miR-145-5p, hsa-miR-21-5p, hsa-miR-196b-5p) were shown.
Conclusions
We constructed a lncRNA-related ceRNA network and identified three hub lncRNAs in recurrent implantation failure. The results may provide further understanding in the pathogenesis of RIF as well as potential diagnostic and therapeutic targets.
Tumor microenvironment-aware, single-transcriptome prediction of microsatellite instability in colorectal cancer using meta-analysis
Authors: Seo Mi-Kyoung , Kang Hyundeok , Kim Sangwoo
Published: November 2021

Detecting microsatellite instability (MSI) in colorectal cancers (CRCs) is essential since it is therapeutic strategy determinant feature, including immunotherapy and chemotherapy. Yet, no attempt has been made to exploit transcriptomic profile and tumor microenvironment (TME) of it to unveil MSI status in CRC. Hence, we developed a novel TME-aware, single-transcriptome predictor of MSI for CRC, called MAP (Microsatellite instability Absolute single sample Predictor). MAP was developed utilizing recursive feature elimination-random forest with 466 CRC samples from The Cancer Genome Atlas, and its performance was validated in independent cohorts, including 1118 samples. MAP showed robustness and predictive power in predicting MSI status in CRC. Additional advantages for MAP were demonstrated through comparative analysis with existing MSI classifier and other cancer types. Our novel approach will provide access to untouched vast amounts of publicly available transcriptomic data and widen the door for MSI CRC research and be useful for gaining insights to help with translational medicine.
Sickness Absence Culture: A Scoping Review
Authors: Pukstad Erlend , Lorentzen Sofie , Låg Torstein , Mykletun Arnstein
Published: November 2021

Background: Several studies show that the absence behavior of co-workers’ influence the absence rates of individual group members so that an employee is more likely to be absent when co-workers are often absent. To our knowledge, there are no systematic scoping reviews or other reviews on the concept of sickness absence culture. The objective of this review is to identify and map existing literature on sickness absence culture. We will also investigate what methods and designs are used.Methods: We will be conducting a systematic scoping review with the aim of getting a broad overview of the preexisting literature. This scoping review will consider any publication on sickness absence culture in the field of human sciences, including also reviews, original research, and opinion pieces. The review will be conducted in accordance with the Joanna Briggs Institute (JBI) methodology for scoping reviews and a populated PRISMA-P checklist (Additional file 1). Two reviewers will independently screen all abstracts for inclusion. We will search the electronic databases: MEDLINE, Embase, PsycINFO, Clarivate Web of Science, BASE and CINAHL. We will use Covidence for data screening and extraction. The final stage will include a narrative synthesis of the data.Discussion: The results of this scoping review will contribute to identifying and mapping the existing literature on sickness absence culture, which could facilitate future research on the topic. Systematic review registration: Not registered in publicly accessible registry.
Satisfaction in Family Health Specialization Courses Offered by the Brazilian Public Health System: a National Assessment
Authors: de Moraes Sílvia Helena Mendonça , Gasque Kellen Cristina da Silva , Cunha Inara Pereira da , Nascimento Débora Dupas Gonçalves do , Lemos Alysson Feliciano , Campos Francisco Eduardo , Nascimento Edinalva Neves
Published: November 2021

Background: This cross-sectional study investigated student satisfaction in specialization courses in family health produced and offered online by the Brazilian Unified Health System’s Open University, along with associated factors.Methods: Health professionals who were enrolled in these courses between 2013 and 2017 responded to online questionnaires collecting data on sociodemographic aspects, student status, and their perceptions about different facets of the courses measured by a Likert scale. Degree of satisfaction was considered as an outcome, and multiple regression analysis was applied.Results: Of the 3,109 respondents, most had successfully completed their course (98.4%), were female (72.5%), self-declared white (62.1%), Brazilians (69%), ≤40 years old (59.1%), nurses (42.1%), or physicians (42.4%). Most respondents viewed the courses positively (59.30%); lower satisfaction score was associated with age (p=<0.0001), education (p=0.0031), and failing the course (p=0.0064). Students reported difficulties with the pedagogical aspects of the courses, but gave positive scores to the materials, contribution to professional practice, and stirring interest in the area.Conclusions: The participants were seen to be satisfied with these courses, although some aspects can be improved.
Paternal melanisation defines wing spot area of male Drosophila nepalensis: supporting evidence through genetic crosses.
Authors: Ramniwas Seema , Singh Divya
Published: November 2021

Males of Drosophila nepalensis show dimorphism in wing melanisation but how they evolve and coordinate during evolution is unknown. Heterogeneity in environment helps individuals to adapt accordingly either through genetic polymorphism or through phenotypic plasticity. In this study, we tried to untangle the genetic architecture underlying differences in wing melanisation in males because in nature the frequency of spotted and spotless males is different. We investigated the variation in wing spot formation in males of D. nepalensis via genetic cross. We found wing spot formation on wings in male is directly correlated to female body melanization. We report that the wing spot of D. nepalensis show very high plasticity and correlated with female body melanization instead of male body melanzation. Only at 21°C temperature we found darker and complete light females, dark female progeny always produced male with spotted wing whereas lighter female produced male without wing spot. The degree of wing melanisation in males of D. nepalensis was assessed to check plasticity patterns. We investigated that increased wing spot area (WSA) is negatively correlated with higher temperature. Finally, we find wing spot is highly correlated in reciprocal progeny due to linkage or pleiotropy which could help in evolution.
Utilization of processed kola nut husk meal in poultry production: Effects on the performance, carcass, biochemical indicators, and antioxidant enzymes of broiler chickens
Authors: Oloruntola Olugbenga David
Published: November 2021

This study looked at the effects of processed kola nut husks meal (PKHM) utilization as a feed ingredient on broiler chicken in a 42-day feeding trial. Kola nut pod husks were processed into a PKHM using ash treatment and rumen liquor fermentation. Three experimental diets were developed at both the starter and finisher phases, with PKHM included at 0, 4, and 8%, and dubbed diets 1, 2, and 3, respectively. In a fully randomised design, 240 Arbor Acres broiler chicks were randomly assigned to three treatments (10 birds per replicate). Except for the significantly improved (P<0.05) feed conversion ratio of broiler chickens fed diets 2 and 3 at the grower phase (22-42 days) and overall (0-42 days), the performance indices were not significantly (P>0.05) affected by PKHM dietary inclusion. Broiler chicken carcass characteristics and relative internal organ weights remained constant (P>0.05) through diets. The serum glutathione concentration in broiler chickens fed an 8 percent PKHM inclusive diet increased significantly (P<0.05) than those on the control diet and 4 percent PKHM inclusive diet. When broiler chickens fed an 8 percent PKHM inclusive diet were compared to those fed a control diet, the serum catalase concentration was significantly higher (P<0.05). The total serum protein, creatinine, alanine aminotransferase, aspartate transferase, and cholesterol levels remained constant (P>0.05) regardless of dietary treatment. Dietary PKHM inclusion of up to 8% enhanced improved feed efficiency and increased antioxidant enzyme concentration and did not affect the serum biochemical indices concentration.Statement of NoveltyKola nut husk is one of the agro-wastes that contributes to environmental deterioration due to its underutilization. The kola nut husk is underutilised in broiler production due to its chemical constitution, minimal nutritional value, and poor digestion. In this research, kola nut husk meal was ash treated and rumen liquor fermented before being integrated at varying levels in the experimental diets and the performance characteristics, antioxidant status, serum protein, enzymes and biochemical were evaluated. The findings of this study could aid in the development of an agro-waste-based, low-cost functional feed for broiler chicks that incorporates the underutilised kola nut husk and other abundant agrowastes as macro-ingredients.
Effect of Cross-section Geometry on Air-Demand Ratio in High-head Conduits With Sluice Gate
Authors: Aydin Alp Bugra , Baylar Ahmet , Ozkan Fahri , Tuna Muhammed Cihat , Ozturk Mualla
Published: November 2021

When the researches on the gated conduits were examined, it was determined that the air-demand ratio changed according to the hydraulic and geometric parameters. However, no study investigated the effect of the cross-section geometry of gated conduits on the air-demand ratio. In this study, the effect of conduit cross-section geometry on the air-demand ratio was examined. Results showed that conduit cross-section geometry was an important effect on the air-demand ratio especially at 10% and 15% gate opening rates. It was seen that the effect of the conduit geometry on the air-demand ratio decreased at 20%, and greater gate opening rates. In addition, a design formula related to the gate opening rate, Froude number, hydraulic radius, and conduit length was presented for estimating the air-demand ratio.
Unified landslide hazard assessment using hurdle models: a case study in the Island of Dominica
Authors: Bryce Erin , Lombardo Luigi , Westen Cees van , Tanyas Hakan , Castro-Camilo Daniela
Published: November 2021

Climatically-induced natural hazards are a threat to communities. They can cause life losses and heavy damage to infrastructure, and due to climate change, they have become increasingly frequent. This is especially in tropical regions, where major hurricanes have consistently appeared in recent history. Such events induce damage due to the high wind speed they carry, and the high intensity/duration rainfall they discharge can further induce a chain of hydro-morphological hazards in the form of widespread debris slides/flows. The way the scientific community has developed preparatory steps to mitigate the potential damage of these hydro-morphological threats includes assessing where they are likely to manifest across a given landscape. This concept is referred to as susceptibility, and it is commonly achieved by implementing binary classifiers to estimate probabilities of landslide occurrences. However, predicting where landslides can occur may not be sufficient information, for it fails to convey how large landslides may be. This work proposes using a flexible Bernoulli-log-Gaussian hurdle model to simultaneously model landslide occurrence and size per areal unit. Covariate and spatial information are introduced using a generalised additive modelling framework. To cope with the high spatial resolution of the data, our model uses a Markovian representation of the Matérn covariance function based on the stochastic partial differential equation (SPDE) approach. Assuming Gaussian priors, our model can be integrated into the class of latent Gaussian models, for which inference is conveniently performed based on the integrated nested Laplace approximation method. We use our modelling approach in Dominica, where Hurricane Maria (September 2017) induced thousands of shallow flow-like landslides passing over the island. Our results show that we can not only estimate where landslides may occur and how large they may be, but we can also combine this information in a unified landslide hazard model, which is the first of its kind.