bluuebunny/crossref_metadata_2025 huggingface dataset:
MULHERES NAS CENAS FINAIS DO EVANGELHO DE MARCOS: NARRATIVA, DISCURSO E TEOLOGIA
Authors: Reimer Ivoni Richter , Souza Carolina Bezerra de
Published: May 2019

O artigo faz uma análise da presença das mulheres nas últimas cenas da vida, morte e ressurreição de Jesus, conforme narrado no Evangelho de Marcos. A partir da perícope 15,40-16,8 objetiva-se contribuir com a reconstrução da partici­pação e da importância das mulheres no movimento de Jesus e na organização de comunidades cristãs no século I, bem como evidenciar tentativas de silenciamento e invisibilização das mesmas. A pesquisa é bibliográfica, deseja-se apresentar uma metodologia exegética que faz uso conjunto de recursos da narratologia e da aná­lise do discurso na interface com hermenêuticas feministas. Esta pesquisa resulta na constatação de que as mulheres receberam uma autoridade ímpar no final do Evangelho de Marcos e que possivelmente eram parte da liderança da comunidade marcana. Teologicamente significativo é perceber que a motivação, a dedicação e a fidelidade na práxis de fé das mulheres baseiam-se na própria ação de Jesus Cristo, que para elas significou acolhida, cura, libertação e reconhecimento.
Correlations between water absorption, electrical resistivity and compressive strength of concrete with different contents of pozzolan
Authors: Medeiros-Junior Ronaldo Alves de , Munhoz Guilherme da Silva , Medeiros Marcelo Henrique Farias de
Published: May 2019

This research confronts the following concrete properties: water absorptions (by immersion and capillarity), electrical resistivity and compressive strength. Concrete mixtures with two types of cement were tested. Results showed that concretes with higher content of pozzolan had higher resistivity and greater absorption by capillarity, for water/cement ratios lower than 0,60. This behavior is attributed to reduced pore diameters and microstructure densification. However, for water/cement ratio of 0,60, concrete with lower content of pozzolan presented higher absorption by capillarity. It was observed that the compressive strength and the electrical resistivity behaved inversely proportional to the water/cement ratio, and the absorption by immersion and capillarity are directly proportional to the water/cement ratio. Correlations with high determination coefficients were found between tests.
Electric Submersible Pump ESP Vibration Characteristics Under Wear Conditions
Authors: Beck David , Nowitzki Wesley , Shrum Justin
Published: May 2019

Abrasive wear to electric submersible pumps (ESPs) and its effects on ESP system performance and failure are the result of a set of interrelated, complex phenomena. Existing literature is replete with theories of relationships and observed indications of relationships amongst wear mechanisms and between wear mechanisms and failure modes; these relationships between wear mechanisms and failure modes can be captured by a set of state diagrams called damage processes. Abrasive wear testing data compiled and analyzed in this work supports the existence of several of these proposed relationships and supports the simultaneous activation of several process that both compete to reach failure modes and reinforce each other to reach a single failure mode. Using test results from several sets of selected pumps, the interplay between pump performance degradation, dimensional changes, and relative vibration peak growth is used to identify which damage processes are active and indicate that, because of the nonlinear relationships amongst damage processes, abrasive wear impacts ESP systems in a nondeterministic fashion.
Accelerating the Shift to a Next-Generation ESP Deployment: Cable Deployed Through Tubing Electrical Submersible Pump TTESP Application
Authors: Zamanuri Kautsar , Yip Pui Mun , Radzuan Nurul Asyikin , Salleh Nurfarah Izwana , Ghonim Elsayed Ouda , Alexander Euan , Bakhtuly Daniyar
Published: May 2019

Most Malaysian oil production is heavily reliant on gas lift. Aging assets experience declining lifting efficiencies due to depleting reservoir pressure and increase in water cut. This impact PETRONAS' capability to deliver national hydrocarbon production targets. New developments and further improvements to gas lift facilities are likely to erode the economic value of assets without even considering the potential time impact due to the complexity in delivering gas compression upgrades or gas import projects. PETRONAS' primary goal within Malaysia is to sustain production and maximize the remaining recoverable reserves. To realize this target it is widely acknowledged that the company must think differently. Alternatives to gas lift have been considered for rejuvenation of brownfield assets and development of marginal assets using a ‘fit for purpose' approach resulting in some relatively low Capital Expenditure (CAPEX)/Operating Expenditure (OPEX) solutions. One such method identified was Through Tubing Electrical Submersible Pumps - Cable Deployed (TTESP-CD). TTESP-CD technology is a game changer that can challenge the boundaries of traditional engineering with a truly rig-less deployment of an ESP system with full compliance to API/ISO requirements and demonstrating up to 70% cost savings over conventional offshore ESP installation methods. The TTESP-CD innovation helps in improving the asset value through gas prioritization, gas lift reallocation, flaring reduction and increase in lifting efficiency. TTESP-CD is also in line with the company digitalization concept due to the baseline data available from surface and downhole equipment.

This technology has been declared a success through pilot deployment in an offshore field within the Sarawak Basin with an incremental gain of 250BOPD, 0.3MMSTB in reserves acceleration and 22 months run life as of Feb 2019. This has been a key step for building confidence in the wider application of the technology. Lessons learnt and best practices from the pilot implementation have been applied to ongoing and future projects and serve as a good foundation for further development of the technology. To date, approximately 20 candidates for the TTESP-CD application have been identified for replication in Malaysia within the next 2 years across 3 regions. There are various challenges faced when implementing this technology on aging offshore assets that was never designed for ESPs which include; space availability for deployment equipment and surface electrical equipment, power availability and distribution, instrumentation, data transmission, structural integrity and operational mind set. PETRONAS sees a bright future for TTESP-CD application and technology which includes layer to layer matrix dump flood, interim production and well unloading/DST well unloading.
Reliability Analysis of High-Power and High-Flow-Rate Subsea ESP Systems in Jubarte
Authors: Vergara Luis , Bacellar Francisco , Neves Marcelo , Watson Arthur , Harris Grant
Published: May 2019

The artificial lift system selected to produce the Jubarte Field uses high-power and high-flow-rate subsea electrical submersible pump (ESP) systems with gas lift as a contingency in case of the need for ESP replacement. The gas lift mandrels are installed in the production well completion. The ESP systems are rated for 1,500 hp at full load and were deployed inside caissons constructed on the seabed, located 210 m downstream of the main production wellhead. The integrated unit is called a pumping module or módulo de bombeio (MOBO) in Portuguese.

Industry perception of average ESP run time, high replacement costs associated with intervention of the subsea ESP systems, and the limited track record available for comparable systems at the time of field development required a comprehensive approach to improve on system reliability from the beginning. The use of advanced technologies to extend the traditional concept of industrial process control to the management of the MOBO systems allowed continuous monitoring of ESPs to maintain operation within the design envelope.

The development of a complete "ESP culture" became a key element connecting the different teams involved in the operation. This required new procedures to be developed, new monitoring and surveillance teams introduced, and, most of all, management of change practices introduced to avoid issues related to the rotation of personnel involved in the operation of the ESP and related systems. The synergies created allowed the provision of timely solutions to face the challenges across the complete production system.

The gap study conducted at the beginning of the Jubarte ESP development identified many barriers and conditions preventing increased system reliability and affecting economic viability of such a large-scale project. This paper builds on such analysis using the operational data gathered during the 8 years of ESP operation, shows improvement in mean time to failure during the period, presents typical failures encountered in equipment and processes, introduces the de-risking process followed to strengthen the system, and provides the reasons behind the enhancements made.

Explanation of the measures proposed to significantly improve the reliability of these 1500-hp subsea ESP systems and the reasoning behind the enhancements will facilitate future projects of a similar nature.
Very Low Frequency Acceptance Testing for an Electric Submersible Pump Cable
Authors: Beck David , Glasscock Terry , Bolliger Dominique
Published: May 2019

Results from two years of validation testing in the Permian region indicate that replacement of direct current (DC) withstand testing procedures with very low frequency (VLF) withstand and tan-delta diagnostic methods promises to provide more accurate and more informative testing with less detrimental effect to cable integrity. The combination of VLF withstand and VLF tan-delta tests, which can both be conducted using the same equipment from HV TECHNOLOGIES, Inc., can provide a more accurate and less intrusive withstand test and a quantitative estimate of cable integrity and defect pattern. Four properties computed from tan-delta measurements, including tan-delta mean, tip-up, tan-delta deviation stability, and tan-delta skirt stability, are examined and upper and lower bounds for acceptance testing are developed for cable testing in the artificial lift industry. For tan-delta mean and tip-up, Korean Electric Power Corporation (KEPCO) degradation classifications should be adopted to enable end-users to make informed risk assessments about cable reuse. In light of a lack of information on the practical significance of stability values, KEPCO criteria for stability should be adopted to identify highly degraded cables without overly pessimistic assessment of cable condition and subsequent needless rejection of good cables. It is feasible to further refine these testing criteria using multi-feature models based on cable run-life and to diagnose cable defect patterns using multi-feature models. Proven methods used in the power distribution industry should be adopted to create artificial lift specific testing criteria and cable run-life models using industry run-life data.
Electrical Submsersible Pump Powered Injection ESPPI Systems Enable the Development of West of the Nile Egypt Assets
Authors: Munoz Miguel , Aboutaleb Mohamed , Dwiggins Jeff
Published: May 2019

Qarun Petroleum Company (QPC), a joint venture between the Egyptian General Petroleum Corporation (EGPC) and Apache Egypt, operates over 350 ESP wells in brownfields across the Egyptian Western Desert. QPC's oil production is heavily dependent on the performance of waterfloods and artificial lift systems. In recent years, QPC entered a development campaign in the West of Nile (WON) region, an area located west of the Nile River approximately 159 kilometers from Cairo. The fertile land has ready access to irrigation and therefore long been developed as an agricultural area, surrounded by densely populated villages. Land access is restricted and operations must be conducted to ensure minimal impact to the environment. Oilfield development in WON is challenging and required alternative solutions to conventional waterflood operations. QPC engineers turned to ESP Powered Injection (ESPPI) systems as an alternative to traditional waterflooding and re-engineered the technology to overcome the operational, economic, and environmental challenges.

ESP Powered Injection (ESPPI) systems utilize conventional ESPs in combination with a bypass system (Y-tool) and an injection string to provide water production and injection support from a single wellbore to one or more wells in the same injection pattern. The system eliminates the need for surface pumping, water separation, storage, and flow lines. QPC has successfully installed and presently operates nine (9) ESPPI systems in the environmentally sensitive WON region of Egypt.

This paper aims to detail the specifications and functionality of ESPPI systems, main challenges and benefits derived from closed monitored installations and operational surveillance, and the economic advantage of its application for QPC.
Alternative ESP Deployment in an Offshore Oilfield Angola, West Africa
Authors: Vierkandt Steven , Olabinjo Lanre , Malone David , English Jack
Published: May 2019

Chevron began development of an offshore oilfield in Angola, West Africa, in 1997 using ESP's as the preferred artificial lift method due to favorable reservoir and fluid characteristics, and limited capacity of the available gas lift injection infrastructure. The initial ESP's were deployed on coil tubing (CT) to reduce initial costs, future ESP replacement downtime and the dependence on the availability of a jack-up rig. Due to difficulties experienced in supporting the CT operations in the remote area, subsequent new completions and ESP replacements have been carried out utilizing standard threaded tubing. To date, there are 28 wells producing with ESP's from 3 platforms.

ESP run life has been excellent over the life of the field with 5-year MTF, and some ESP's surviving longer than 10 years. However, when an ESP fails it must compete with other economic opportunities within the +600 well portfolio for rig time to replace the failed equipment and return to production. Over time increasing rig day rates and declining oil production rates have created challenging economics. Typically, more than one ESP failure on a platform is required to provide competitive project economics to justify mobilizing a rig, resulting in well downtime increasing to an average of over 12 months.

This paper describes the process undertaken to evaluate and select an alternative deployed ESP system to significantly reduce workover costs and time-waiting-on-replacement, improve economics and ensure continued field development. This was a collaborative effort of more than a dozen partners, service companies and contractors across 3 continents. It includes detailed evaluation of the existing well bores and requirements for the new ESP's. Requirements comprised a new wellhead design, larger tubing (resulting in tighter tolerances), a new cable clamp design, VFD controller certification, confirming pumps could be replaced on tractor due to high well deviation, etc. One example was the decision to perform the ESP connector head, motor lead cable and ESP cable splices in a US factory to improve reliability and reduce time over rig floor connections. Multiple FIT tests were performed and evaluated to ensure project success.

The first two new alternatively deployed ESP's were successfully installed and placed on production in June 2017. A surface electrical failure in a VFD in early 2018 resulted in a damaged downhole ESP motor in one well. The motor was successfully retrieved and replaced via wireline tractor, at a hole angle of 88°, under pressure, without killing the well. The well was successfully returned to production in August 2018.
Improving Gas Separation in ESP for Unconventional Wells in 5-1/2" Casing. Case Studies in the Permian Basin
Authors: Gonzalez Gustavo , Loaiza Carlos
Published: May 2019

New unconventional wells have been a huge challenge for ESPs in the Permian Basin due to horizontal wells with high-formation GORs or GLRs. The pumped fluid can cause issues such as gas interference, gas locking, short run life, low production, poor energy efficiency, increased failure rates, shutdowns, so forth. A major problem is gas presence around the ESPs, because it causes the motor to rapidly overheat since the gas is incapable of adequately cooling.

In short term, the presence of gas in the flow reduces the pump efficiency and in severe conditions leads to gas lock in the impeller which could damage the equipment. In the long term, the motor life is shortened as a function of the temperature increase. In general, for every 18F of operating temperature increase, the life of the insulation material is reduced by 50% and leading the motor material to be severely affected. The gas handling capacity of standard ESPs is very low, and the efficiency of the traditional rotary gas separator might not be as expected that is why a new and innovative downhole gas separator has been introduced in recent applications to combat the gas slug's problems.

The new gas mitigation technology consists of a shrouded ESP with a double stage of gas separation connected at the bottom of the shroud that act as intake and was designed to break the gas slugs and avoid gas entrance into ESPs by forcing free gas to go around the shroud and produce through the casing. The fluid is now forced to pass through an additional gas separator (New Gas Mitigation Technology), which helps on gas mitigation as well as lower motor temperature

This paper summarizes different case studies in wells located in the Permian Basin that had reported frequent shutdowns due to gas lock and high motor temperature. All the pump parameters are analyzed before and after the installation to conclude on optimization; in these wells, an increase on production was observed, and better performance of the pump. Other results observed were the reduction of the shutdowns and no gas mode with stable condition along with significantly breaking the drawdown barrier of the 700 psi (ESP PIP). This success was noted on most of our wells where the lowest of them operated at 290 psi (ESP PIP). Additionally, some operational and analytics guides are provided to understand how to identify and control the gas problem in ESPs.
The genome of horseshoe crab Tachypleus tridentatus reveals its evolutionary scenario and well-developed innate immunity
Authors: Zhou Yan , Liang Yuan , Yan Qing , Zhang Liang , Chen Dianbao , Ruan Lingwei , Kong Yuan , Shi Hong , Chen Mingliang , Chen Jianming
Published: May 2019

Background

Horseshoe crabs are ancient marine arthropods with a long evolutionary history.

Results

Here, we describe the 2.06 Gbp genome assembly of Tachypleus tridentatus with predicted 24,222 protein-coding genes. Comparative genomics show that T. tridentatus and the Atlantic horseshoe crab Limulus polyphemus had the most orthologs shared in only these two species, including genes involved in immune related Jak/STAT signaling pathway. Divergence time dating results show that the last common ancestor of Asian horseshoe crabs (including T. tridentatus) and L. polyphemus appeared at about 130 Mya (121-141) and the split of two Asian horseshoe crabs was dated to about 63 Mya (57-69). Hox gene analysis suggests two clusters in both horseshoe crab assemblies. Surprisingly, selective analysis of immune related gene families revealed high expansion of conservatively presented pattern recognition receptors. Genes involved in IMD and Jak/STAT signaling transduction pathways also exhibited a certain degree of expansion in both genomes. Intact coagulation cascade related genes were presented in T. tridentatus genome with a higher number of coagulation factor genes. Moreover, most antibacterial peptides reported have been identified in T. tridentatus with their potentially effective antimicrobial sites.

Conclusions

The well-developed innate immunity of T.tridentatus may affect the quality of the adaptive properties with regard to complicated marine environments.
Phytotoxicity of Methiozolin on Fine Fescue
Authors: Qu Yuanshuo , Daddio Ryan M. , McCullough Patrick E. , Bonos Stacy A. , Meyer William A.
Published: May 2019

Methiozolin is a new herbicide that controls annual bluegrass (Poa annua) in turfgrasses, but the differential tolerance levels of fine fescues (Festuca sp.) has received limited investigation. The objective of this study was to investigate the potential injury from methiozolin when applied to chewings fescue (Festuca rubra ssp. fallax), strong creeping red fescue (Festuca rubra ssp. rubra), and hard fescue (Festuca brevipila). Nine different fine fescue populations (14W2 Comp, Fairmont, and Survivor chewings fescue; FT345, Miser, and Fenway strong creeping red fescue; and 14H4 Comp, Stonehenge, and Oxford hard fescue) were sprayed with methiozolin at five different rates (0.42, 0.83, 1.25, 1.67, and 2.09 lb/acre) at four different application timings [4 weeks before seeding (WBS), 2 WBS, at seeding (AS), and 2 weeks after germination (WAG)]. Untreated controls were also included for each combination. Significant reduction in germination of fine fescue was observed when methiozolin was applied before emergence for all tested application rates. Methiozolin at 1.25, 1.67, and 2.09 lb/acre applied before or at the day of seeding led to complete inhibition of germination in all fine fescue species tested. It was less injurious compared with methiozolin applied at 2 WAG, although a reduction in the percentage of green cover and biomass was observed for application rates greater or equal to 0.83 lb/acre. The hierarchical ranking of species injury from high to low is as follows: hard fescue, chewings fescue, and strong creeping red fescue. A possible solution for annual bluegrass control in fine fescue species with methiozolin is multiple postemergence applications up to a maximum rate of 0.83 lb/acre. Turf managers need to make adjustments in methiozolin application rates and timings based on fine fescue species to maximize selectivity for annual bluegrass control.
Near end-member shenzhuangite, NiFeS2, found in Muong Nong-type tektites from Laos
Authors: Křížová Šárka , Skála Roman , Halodová Patricie , Žák Karel , Ackerman Lukáš
Published: May 2019

Australasian Muong Nong-type tektites from the locality centered at 16.46150° N, 106.48917° E in Laos contain sporadic spherical heterogeneous sulfide inclusions less than 10 μm in diameter, which have been identified by electron probe microanalyzer and electron backscatter diffraction to represent a mixture of rare mineral shenzhuangite with a pyrrhotite polytype (possibly troilite). Contrary to type shenzhuangite found in the shocked L6 chondrite Suizhou, the mineral embedded in the tektite glass is nearly free of copper, making the composition close to its expected end-member that has not yet been found in nature; the empirical formula closest to ideal end-member composition based on four atoms per formula unit is Ni1.007Fe0.998Cu0.016Co0.058S1.922. The described occurrence also represents the first find of shenzhuangite in terrestrial material. Presented is the Raman spectrum for shenzhuangite with the tentative assignment of spectral bands based on the analogy with synthetic chalcopyrite-structured phases. The chemical composition of shenzhuangite close to NiFeS2 is not consistent with any stable phase in the Fe–Ni–S system up to melting temperature. Available data so far on phase relations in this system do not allow unambiguous interpretation of conditions under which the sulfide association within inclusions had formed.
Monazite and xenotime solubility in hydrous, boron-bearing rhyolitic melt
Authors: Rusiecka Monika K. , Baker Don R.
Published: May 2019

We conducted a series of monazite and xenotime dissolution experiments in a boron-bearing silicic melt at 1000–1400 °C and 800 MPa in a piston-cylinder apparatus. We present new measurements of monazite and xenotime solubility in hydrous (~3 wt% water), boron-bearing rhyolitic melts, as well as the diffusivities of the essential structural constituents of those minerals (LREE, P, and Y). We compare our results to the previous studies and discuss the implications of this study on the understanding of natural, silicic (granitic/rhyolitic) systems.

We propose one equation describing the relationship between the solubility of xenotime and temperature in hydrous rhyolitic melts:

ln ⁡ Y = 18.3 ± 0.3 − 125499 ± 3356 R T

and another for monazite:

ln ⁡ Σ LREE = 18.6 ± 1.5 − 129307 ± 18163 R T .

In the presence of sufficient phosphorous, the concentration of LREE needed for monazite saturation is within the uncertainty of the Y concentration needed from xenotime saturation and indicates that in the case of equilibrium crystallization the mineral that forms will only depend on the availability of LREE and Y and HREE. Given the similarity of the solubility of xenotime to that of monazite, we propose that previously published models of monazite solubility in silicic melts can potentially be applied to xenotime, and could, like monazite, serve as a geothermometer.

In the case of disequilibrium crystallization in front of rapidly growing crystals, Y will diffuse faster than LREE and xenotime will only crystallize when LREE are depleted. We also found that the diffusion of Y is greater than the diffusion of P from dissolving xenotime, unlike the similar diffusivities of LREE and P during monazite dissolution. The significant difference between Y and P diffusivities suggests that the components forming xenotime diffuse as separate entities rather than molecular complexes.

The dissolution of phosphates (monazite, xenotime, apatite) in hydrous, silicic melts with the addition of boron leads to liquid-liquid immiscibility at high temperatures where the saturation values of P and either light rare earth elements or Y are in the weight percent range. Immiscibility is not observable at low, magmatic temperatures, most probably due to the lower concentrations of P2O5 necessary for phosphate saturation at these conditions; however addition of other components, notably F, may result in liquid-liquid immiscibility at magmatic temperatures.
A prisão preventiva no ordenamento jurídico brasileiro: entre a proteção do acusado e a antecipação da pena presumida
Authors: Duarte Samuel Correa
Published: May 2019

O Estado capitalista estabelece uma relação espúria entre a promoção da privação de liberdade e da segurança individual que implica num acirramento do processo de encarceramento. Para abordar esse tema, na primeira parte do texto nos reportamos ao debate de matriz weberiana sobre racionalização e ascensão de uma ordem burocrática como marcas da modernidade. Na segunda parte descrevemos como o ordenamento jurídico brasileiro projetou a “prisão” enquanto arcabouço legal e aparato institucional. A seguir apresentamos o caso das excessivas prisões preventivas como modelo exemplar de uma reversão do Estado de Direito. Concluímos que o uso indevido da prisão preventiva como antecipação de pena fere os direitos fundamentais levando a consequências como a substituição do poder público pelo crime na gestão do sistema prisional e o reforço à exclusão como tônica do sistema.
Internet-Based Intervention for Postpartum Depression in China: Formative Research and Design of the “Mommy go” Program (Preprint)
Authors: Li YuHong , Mu TingYu
Published: May 2019

UNSTRUCTURED

Background: Postpartum depression (PPD) is a significant public health problem affecting approximately 13% of women. There is strong evidence supporting Internet-based intervention for PPD. The prevalence of PPD can be reduced by early screening the high-risk population of PPD through Internet intervention. To date, however, Web-based interventions have not been used and evaluated specifically for the treatment of PPD in China.
Objective: We describe the formative work that contributed to the development of our Internet-based intervention (“Mommy go”) for helping to provide maternal information and emotional support to reduce the risk of PPD, and the design and key components of the program.
Methods: The study is based on the method of constructing a health intervention strategy proposed by the multiphase optimization strategy (MOST). Firstly, to select the important components for intervention based on systematic review. Secondly, conducting maternal individualized interviews to understand maternal awareness of PPD, health education needs, and suggestions on “Mommy go”. Thirdly, an Internet intervention strategy for PPD is formed. Then, cooperate with Internet technicians to construct the prototype of “Mommy go”. Finally, using usability test to understand the maternal feedback on the use of “Mommy go” and making appropriate adjustments to the functionality and content of “Mommy go”.
Conclusions: An overview of the eventual design, architecture, and key program ingredients of the“Mommy go” provides pregnancy and postnatal maternal and child health care knowledge for pregnant women and systematically assess the health of women during pregnancy and childbirth (including monitoring, intervention, and feedback).
Building a smart city with trust: the case of ‘156 central’ of Curitiba-Brazil
Authors: Hojda Alexandre , Dallabon Fariniuk Tharsila Maynardes , Simão Marcela de Moraes Batista
Published: May 2019

Curitiba is an example of government/citizen interactions, the "156 Central", a call center created in the 1980s to establish a direct means of communication between citizens and city hall. The main goal of this article is to analyze the process of state/citizen management in Curitiba, linking it to the concepts of Smart Cities and trustworthiness, based on the experience of the 156 Central. The methodology involves documental and statistic research, as well as in-depth interviews and a comparative analysis. In this way, the 156 Central improve the communication and integration between actors increasing the trustworthiness and effectiveness of the services provided in the city.
Agrupamientos industriales de la economía del estado de Hidalgo, México: un enfoque de insumo-producto
Authors: Gaytan Alfaro Edgar David , Vargas Sánchez Juan Roberto
Published: May 2019

El aporte del estudio es la identificación de la estructura económica del estado de Hidalgo, México, mediante el esclarecimiento de sus agrupamientos industriales. Para ello, se utiliza el análisis de factores y componentes principales y se ubican siete agrupamientos. En los dos primeros prevalecen las actividades económicas del sector terciario, en los cinco restantes predominan las del secundario; las del sector primario son escasas y aparecen de forma modesta en tres agrupamientos. Lo anterior tiene un antecedente histórico y es coherente con la producción y el empleo actuales de la entidad. El documento contribuye al estado del arte de la economía regional de las entidades de México.
DEVELOPMENT AND VALIDATION OF STABILITY INDICATING HPTLC METHOD FOR DETERMINATION OF APIXABAN AS BULK DRUG
Authors: Damle Mrinalini C. , Waghmare Swapnil S , SINHA PURUSHOTAM
Published: May 2019

Objective: To develop and validate simple, sensitive stability indicating HPTLC (High performance thin layer chromatography) method for apixaban.

Methods: The chromatographic separation was performed on aluminium plates precoated with silica gel 60 F254 using toluene: ethyl acetate: methanol (3:6:1 v/v/v) as mobile phase followed by densitometric scanning at 279 nm.

Results: The chromatographic condition shows sharp peak of apixaban at Rf value of 0.38±0.03. Stress testing was carried out according to international conference on harmonization (ICH)Q1A (R2) guidelines and the method was validated as per ICH Q2(R1) guidelines. The calibration curve was found to be linear in the concentration range of 100-500 ng/band for apixaban. The limit of detection and quantification was found to be 11.66ng/bandand35.33ng/band, respectively.

Conclusion: A new simple, sensitive, stability indicating high performance thin layer chromatographic (HPTLC) method has been developed and validated for the determination of apixaban.
EXPRESSION PROFILING OF SELECTED MICRO RNAs COUPLED WITH MOLECULAR AND BIOCHEMICAL ANALYSES OF ASIATICOSIDES IN CENTELLA ASIATICA (L.)URB IN VITRO
Authors: S. JISHA , S. HEMANTHAKUMAR A. , R. GOURI P. , K. SABU K.
Published: May 2019

Objective: Centella asiatica (L.) Urb from Umbelliferae is a potential source of secondary metabolites having immense medicinal value. Asiaticoside is the major therapeutic compound. In the present study, Identification of a possible relationship between concentration/transcript level expression of asiaticoside and concentrations of growth hormones at different growth stages was observed. The current study includes molecular and biochemical evaluation of stress generated in C. asiatica at different time intervals in vitro.
Methods: The enhancement in auxin, cytokinin and final asiaticoside content were determined using immunoassay kits for auxin, cytokinin and HPLC analysis respectively. Transcript level expression at different growth phases was carried out using real-time RT-PCR. For isolation of stress-related miRNAs, reverse transcription of total RNA using miScript II RT Kit PCR System was carried out as per instructions. The differential expression of five selected miRNAs was done by Real-Time RT-PCR. The analysis of stress in vitro was done by quantification of Hydrogen Peroxide (H2O2), total phenolics and total antioxidants by H2O2 assay kit, total antioxidant assay kit and Folin Ciocalteau reagent respectively. The final asiaticoside content was determined by HPLC.
Results: Differential expression of key genes involved in asiaticoside pathway showed significantly higher transcript expression, which is in correlation with the final asiaticoside content. The enhanced expression of miRNAs and the analysis of H2O2, total antioxidant capacity and total phenolics are suggestive of generation of oxidative stress under controlled conditions.
Conclusion: The present study shows a direct correlation between oxidative stress and transcript/phytochemical estimation of asiaticoside content under in vitro conditions.
Secure Data for the Future: A Risk Assessment
Authors: Bryde Bendik , Gonzalez Roberto
Published: May 2019

The guarantee of secure and authentic future access to any digital data is a big worry to those who work with data now and those who are responsible to keep it accessible for the future. There are a wide range of threats to digital data that these people should need to take into consideration. The project PreservIA had the goal to assess the risks of using analogue 35mm film to store and preserve digital information and define its strengths and weaknesses for long-term secure preservation of all kinds of digital data.

The research project was examining the application of the Piql technology to ensure the security, integrity and authenticity of the information stored on a unique storage medium. PiqlFilm has been designed for a life span of 500 years or more and the research tries to assess how well this solution could maintain the authenticity and availability of the information, independently of internal and external changes in the surrounding environment over time.

The research project has been designed using a scenario-based approach and the morphological method of scenario development is used to define a set of scenarios covering the risks to the service.

The scenario classes used were accident, technical error, natural disaster, crime, sabotage, espionage, terrorism, armed conflict and nuclear war. A scenario template has been included for the purpose of describing current and future scenarios. The final scenario analysis identified potential vulnerabilities.

The paper shows briefly how Piql Preservation Services holistic preservation approach perform the work, defines a methodology to select the scenarios for the assessment and then studies the vulnerabilities and security challenges of the solution on those scenarios. The project also includes a comparison of other existing storage media to evaluate their robustness to the addressed scenarios in relation to Piql technology.
Implementasi Version Control System untuk meningkatkan kwalitas Manajemen Proyek Sistem Informasi
Authors: Isnardi Is
Published: May 2019

Skill dan Team Work  sangat dibutuhkan demi kelancaran pekerjaan dan harmonisasi dalam menyelesaikan sebuah proyek Sistem Informasi, memperoleh keduanya dari tamatan perguran tinggi Sistem Informasi dan Manajemen Informatika hari ini sangatlah sulit, banyak perusahaan kesulitan mendapatkan tenaga yang memenuhi kriteria keduanya dari alumni Perguruan Tinggi, hal itu disebabkan oleh  tidak di persiapkan dari Perguruan Tinggi sewaktu di bangku kuliah, maka untuk mengatasi hal itu perlu di terapakan system yang bisa menggabungkan keduanya terutama pada mahasiswa jurusan informatika, pada penelitian ini penulis menerapkan Version Control System (VCS),  dari penelitian ini mahasiswa akan terbiasa bekerja secara kalaborasi, saling memberi masukan, bekerja sesuai dengan job masing-masing, hasil kerja bisa di gabungkan, sehingga mempercepat proses penyelesaian sebuah proyek sistem informasi. Disamping itu di perlukan juga harmonisasi sebuah tim yang akan menambah semangat dan inovasi kerja, Sehingga dapat di simpulkan bahwasanya penggunaan VCS sangat membantu dalam manajemen proyek sistem informasi.
PENYEWAAN ONLINE WEDDING ORGANIZER BERBASIS WEB
Authors: Maiyana Efmi
Published: May 2019

Wedding organizers help prospective brides and families in the planning and implementation of a series of wedding events in accordance with the schedule and budget that has been set by offering various concepts of marriage but prospective brides have difficulty knowing the WO is constrained by a number of things such as lack of information, difficulties in ordering and takes time to visit WO places. Constraints The website is a forum for wedding organizer promotions to brides that can be accessed at any time where the system is designed using the PHP programming language and MySQL database. The aim of the research is to design a web-based Wedding Organizer (W0) information system so that prospective brides can find wedding concepts desired is adjusted based on the number of invitations, finance, catering, buildings, and bridal aisle decorations while for service providers is the promotional media WO has so that it runs a wedding organizer business process that connects service providers with consumers through electronic transactions using the internet.
Customized exposure strategies for manufacturing hybrid parts by combining laser beam melting and sheet metal forming
Authors: Huber Florian , Papke Thomas , Kerkien Melanie , Tost Florian , Geyer Georg , Merklein Marion , Schmidt Michael
Published: May 2019

Subjects of this work are the mechanical, geometrical, and microstructural properties of hybrid parts from Ti6Al4V sheet metal bending and laser beam melting (LBM) in dependence of the extended LBM process parameters. In this context, the effects of different laser exposure strategies for the interface area to increase the reproducibility of the joint strength are investigated. Also, the effect of varying scan patterns and two different laser beam sources (Gaussian beam profile, spot size: 120 μm, maximum laser power: 400 W and irregular beam profile, spot size: 680 μm, maximum laser power: 1000 W) on the LBM process and the resulting distortion of the parts are examined. Furthermore, three heat-treatment temperatures at 450, 850, and 1050 °C were applied to the hybrid samples, resulting in variable microstructures and different mechanical properties for the sheet metal body and the LBM structure.
Falla cardiaca
Authors: Gaus David
Published: May 2019

La falla Cardiaca (FC) es un síndrome caracterizado por disnea, cansancio, y frecuentemente con signos de hipervolemia. La hipertensión arterial, y la diabetes, junto con la enfermedad cardiaca reumática contribuyen a su prevalencia creciente en Ecuador. La clasificación de la American Heart Asociacion (AHA) permite una estrategia terapéutica más proactiva que la antigua clasificación de NYHA. Las cinco causas de FC son distintas a los desencadenantes. La ecocardiografía es el estándar de oro para confirmar el diagnóstico cuando está disponible. El tratamiento farmacológico con Inhibidores del Enzima de Convertidor de Angiotensina (IECAs), Beta bloqueadores, y Diuréticos está dirigido a la fisiopatología neuro-hormonal de la enfermedad. Nuevos fármacos que demuestran beneficio en ciertos pacientes incluyen los antagonistas de receptores de angiotensina/inhibidor de Neprilysina y moduladores del nodo sinusal. Otros fármacos como Digoxina, Espironolactona, y Isosorbida Dinitrato/Hidralazina están indicados en ciertos pacientes.
MODIFIKASI KONSEP PARTICIPATORY RURAL APRAISAL UNTUK PEMBEKALAN KULIAH KERJA NYATA MAHASISWA DI JAWA BARAT, INDONESIA
Authors: Zakaria Zufialdi
Published: May 2019

Modifikasi konsep PRA (Participatory Rural Appraisal) diperlukan bagi mahasiswa pada kegiatan KKN di provinsi Jawa Barat, Indonesia. Konsep modifikasi PRA  dapat digunakan sebagai alat komunikasi mahasiswa dengan penduduk desa lokal. Berbagai jenis gerakan tanah (longsor) terjadi di wilayah Jawa Barat. Jawa Barat menjadi wilayah yang paling rawan di dunia. Mahasiswa peserta KKN perlu dilengkapi dengan pengetahuan tentang kondisi wilayah Jawa Barat berdasarkan aspek geologi umum, juga mengenali informasi risiko dan bencana gerakan tanah, memahami penggunaan aplikasi Android yang berkaitan dengan bencana geologi, mahir menggunakan smartphone, mengetahui. beberapa metode penyampaian informasi dengan mudah dan komunikatif. Komunikasi yang baik dengan masyarakat lokal merupakan bagian dari tugas siswa sebagai salah satu agen pentahelix dalam Model Starlet (Stabilisasi dan Rancangbangun Lereng Terpadu). Hasil Pre-Test 58 mahasiswa menunjukkan bahwa 98% belum mengetahui konsep PRA, 91% belum mengetahui konsep pentaheliks dalam model Starlet, 82% tidak mengetahui bahwa Jawa Barat sangat rawan gerakan tanah, 88% belum mengenal konsep Sistem Informasi Geografis Aplikasi Penanganan Bencana Gerakan Tanah (SIGAP Bencana Gerakan Tanah), 83% belum mengenal model Starlet (Stabilisasi dan Rancangbangun Lereng Terpadu). Sebanyak 98% mahasiswa dapat membedakan resiko dan bencana, 72% dapat membedakan kerentanan dan bahaya, dan 100% mereka memerlukan suatu metode penyuluhan agar masyarakat pedesaan mudah menerima informasi dan mengetahui penanganannya.
UPAYA PENINGKATAN NILAI TAMBAH PRODUK SAYURAN ORGANIK DI DESA CIBODAS KECAMATAN LEMBANG KABUPATEN BANDUNG BARAT
Authors: Budi Kusumo Rani Andriani
Published: May 2019

Pemerintah Kabupaten Bandung Barat menetapkan Desa Cibodas sebagai salah satu Desa Organik. Program Desa Organik saat ini lebih difokuskan pada kegiatan mendorong praktek pertanian yang ramah lingkungan. Kelompok PKK Desa Cibodas Kecamatan Lembang berupaya untuk mendukung gerakan Desa Organik dengan menciptakan nilai tambah dari produk sayuran organic yang merupakan salah satu komoditas unggulan di Desa Cibodas. Kegiatan pengolahan mie sayuran organic diharapkan dapat meningkatkan nilai tambah produk sayuran organic yang selaras dengan gerakan Desa Organik dan juga berpotensi meningkatkan pendapatan keluarga petani.  Kegiatan Pengabdian Kepada Masyarakat ini bertujuan untuk : 1) Meningkatkan kesadaran masyarakat, khususnya mitra PKM mengenai peluang usaha pengolahan sayuran organik menjadi produk mie organik; 2) Berkembangnya gerakan Desa Organik di Desa Cibodas, dengan diversifikasi usaha produk sayuran organik. Metode pelaksanaan dari kegiatan ini adalah : 1) Pelatihan  pembuatan mie berbahan baku sayuran organic; 2) Penyuluhan peluang usaha produk olahan sayuran organik; 3) Pendampingan pada mitra. Kegiatan PKM ini telah memberikan perubahan pada aspek pengetahuan dan keterampilan peserta dalam meningkatkan nilai tambah produk sayuran organic melalui kegiatan pengolahan mie organic. Melalui kegiatan PKM diperoleh inisiasi dari pihak Desa Cibodas untuk mengembangkan beragam produk olahan dari sayur organic sebagai produk unggulan Desa Cibodas.
PEMBERDAYAAN MASYARAKAT DESA CISEWU BERBASIS POTENSI LOKAL DALAM MEWUJUDKAN MASYARAKAT TANGGAP BENCANA
Authors: Sukiyah Emi , Aton Patonah , Zufialdi Zakaria , Devnita Rina , Sudradjat Adjat , Haryanto Edi Tri , Purnomo Dwi
Published: May 2019

Desa Cisewu berada di Kabupaten Garut bagian selatan. Wilayah ini merupakan bentangalam perbukitan yang tersusun oleh material vulkanik berumur Kuarter. Struktur geologi  berupa kekar dan sesar di kawasan tersebut menambah risiko lahan bersifat labil. Oleh karena itu wajar jika kawasan tersebut rawan gerakan tanah. Populasi penduduk berkembang pesat mengingat wilayah ini strategis. Apalagi wilayah Cisewu merupakan penghubung, antara Jawa Barat bagian tengah dan selatan. Sebagian masyarakat Desa Cisewu telah berulang kali mengalami kerugian akibat bencana longsor. Relokasi warga hampir sulit dilakukan, mengingat budaya masyarakat setempat yang sulit meninggalkan tanah leluhur. Masyarakat Desa Cisewu perlu diberdayakan agar mampu berdikari serta tanggap terhadap darurat bencana gerakan tanah. Pemberdayaan masyarakat dapat dilakukan dengan cara memberikan berbagai pelatihan dan pendampingan dengan metode yang mudah dipahami. Pemahaman wilayah yang labil bisa disisipkan pada berbagai kegiatan dalam rangka pemberdayaan masyarakat. Sosialisasi beragam fenomena alam terkait kebencanaan perlu dilakukan dengan bahasa yang sederhana dan sesuai dengan tingkat pendidikan masyarakat setempat. Di sisi lain, masalah konservasi kawasan rawan bahaya alam juga perlu disosialisasikan. Target masyarakat dapat dikelompokkan berdasarkan usia dan latar belakang pendidikan. Pengembangan usaha berbasis potensi lokal perlu mendapat perhatian khusus. Potensi lokal ini perlu mendapat pendampingan untuk dapat bersaing dengan produk unggulan di daerah lainnya.
TEKNOLOGI PENGOLAHAN EMPING JUBIKA SEBAGAI UPAYA PENINGKATAN NILAI GUNA JAGUNG MANIS DI DESA ARJASARI KABUPATEN BANDUNG
Authors: Djali Mohamad , Kayaputri Indira Lanti , Kurniati Dian
Published: May 2019

Desa Arjasari dikenal dengan desa yang kaya akan kekayaan alamnya. Salah satu komoditas yang diunggulkan pada kekayaan alam desa tersebut adalah jagung manis. Namun pemanfaatan hasil panen jagung manis ini belum maksimal karena masih terbatas pada penjualan hasil panen pada tengkulak dan produk olahan tradisional. Oleh karenanya perlu dilakukan upaya peningkatan nilai guna dari jagung manis di Desa Arjasari, salah satunya dengan membuat produk olahan yang mempunyai nilai ekonomi lebih tinggi dan menarik untuk dipasarkan dalam bentuk emping JUBIKA (Jagung Kulit Biji kakao). Tujuan dari program pengabdian masyarakat ini adalah transfer teknologi tepat guna pengolahan jagung manis menjadi produk olahan yang memiliki nilai ekonomi yang lebih tinggi sehingga dapat meningkatkan nilai guna jagung manis, memperpanjang umur simpan, dan berpotensi memberikan kontribusi kepada masyarakat baik petani jagung manis maupun pengolahan makanan dalam bentuk margin ekonomi. Metode pendekatan dilakukan melalui pendekatan partisipasif dengan kegiatan survey lokasi dan potensi desa, pelatihan baik teori atau praktek, monitoring dan evaluasi, dan persiapan pemasaran. Dari kegiatan yang telah dilakukan dapat disimpulkan bahwa masyarakat desa Arjasari kecamatan Arjasari kabupaten Bandung terutama Ibu-ibu PKK, petani jagung manis, tokoh masyarakat, dan Karang Taruna menyambut baik kegiatan PPMD bertopik pembuatan JUBIKA, pengembangan olahan berbahan baku jagung ke depan dinilai memungkinkan karena ditunjang kesediaan bahan baku jagung manis di desa tersebut dan pada kegiatan PPM tahun berikut akan dilaksanakan pengembangan untuk produk olahan singkong dan pisang yang merupakan produk khas daerah setempat.