bluuebunny/crossref_metadata_2025 huggingface dataset:
BERGENIA CILIATA: ISOLATION OF ACTIVE FLAVONOIDS, GC-MS ANALYSIS, ADME STUDY AND INHIBITION ACTIVITY OF OXALATE SYNTHESIZING ENZYMES
Authors: GOPHANE SHWETA R. , JADHAO SAGAR R. , JAMDHADE PREETI B.
Published: November 2021

Objective: Bergenia ciliata (family-Saxifragaceae) is a well-known herb for kidney stone. The main objective of the study was the identification of flavonoids along with ADME profile. Another supportive objective was to check inhibition of enzymes which perform active role in oxalate synthesis.
Methods: The hydromethanolic extract was fractionated by liquid-liquid extraction to obtain ethyl acetate and ethyl ether fractions. The chemical structures of the purified compounds were identified by gas chromatography-mass spectrometry.
Results: A total of 12 volatile chemical compounds belonging to hydrocarbons, esters, alcohols, fatty acids, ketones, etc. were identified and characterized in ethyl acetate fraction through GC-MS analysis Fractions enriched in flavonoids showed glycolate oxidase and lactate dehydrogenase enzyme inhibition with IC50 value (µg/ml) 65.76 and 69.84 respectively. The kinetic behaviour of the extracts that inhibit the Glycolate oxidase and Lactate dehydrogenase activity was determined by the Lineweaver-Burk plot. The mode of inhibition of the studied plant extract was type of a non-competitive inhibition. ADMET screening of compounds successfully passed all the parameters of screening.
Conclusion: On the basis of the results, it was found that Bergenia ciliata (rhizome) may serve as a novel and rich source of therapeutic compounds and it can be further explored for urolithiasis treatment purposes.
THE ROLE OF A SPECIALIST PHARMACIST IN THE MANAGEMENT OF ADALIMUMAB IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE
Authors: HEGNER JOHANNES , PATEL JANKI , FONG STEVEN , JEFFS SIMON
Published: November 2021

Objective: The management of inflammatory bowel disease (IBD) patients on complex medications such as biologic disease-modifying anti-rheumatic drugs (DMARD) requires close supervision. At East Sussex NHS Healthcare Trust (ESHT), the multi-disciplinary team (MDT) already looking after these patients could benefit from the additional knowledge and support from a specialist pharmacist (SP).
Methods: To assess if the MDT could benefit from an SP, all IBD patients on the DMARD adalimumab were identified. The patient records were screened for patient demographic data, clinical assessment and investigations, treatment, and follow-up clinics.
Results: 162 patients at ESHT were identified as being on adalimumab treatment for either Crohn’s Disease (77%) or Ulcerative Colitis (23%). Disease activity scores, a clinical measure of IBD severity, were infrequently recorded (1%) on patient letters. Evidence of a biologic screen, a series of investigations to ensure safety in a biologic treatment, was only evident in one-third of patients. Clinic review of patients recently started on adalimumab and annual review of stable patients occurred 43% and 26% respectively.
Conclusion: The results indicate that there is a need for an additional member to support the IBD MDT in managing this cohort of patients. An SP is uniquely positioned to fill this gap. They have extensive knowledge in drug indication, therapeutic drug monitoring, and side-effect profiles. Similar studies have been identified that support SP in this role.
A PROSPECTIVE OBSERVATIONAL STUDY ON THE ASSESSMENT OF POTENTIAL DRUG-DRUG INTERACTIONS AND MANAGEMENT OF POST-COMPLICATIONS IN STROKE PATIENTS AT A TERTIARY CARE TEACHING HOSPITAL
Authors: SULTANA MAHE NAAZ , QURESHI SABA YOUNUS , FATIMA IQRA , JABEEN WAJIDA , OBAID MOHAMMED
Published: November 2021

Objective: The objective of the study is to determine the occurrence, frequency, and severity of significant drug-drug interactions in stroke patients, with an emphasis on post complications and their symptomatic management.
Methods: A prospective observational study was carried out for 6 mo at Osmania General Hospital, a Tertiary Care Teaching Hospital. The prescriptions taken by stroke patients throughout their hospital stay were analyzed for possible interactions using-Micromedex-2 (Thomson Reuters) × 2.0.
Results: A total of 130 prescriptions was analyzed in the study in which 141 drug-drug interactions were found with a male predominance of 85.4%. The majority of interactions were of moderate severity (74.46%) and pharmacokinetics (67.37%) in nature. Among the clinical consequences, decreased atorvastatin efficacy (49.10%) was found to be the highest. The class of drugs most commonly involved in drug-drug interactions was found to be anti-epileptics and statins. 60.15% of the study population were identified with one complication, among which seizures account for 15% of patients. All the complications allied with the condition were treated with drug classes in the study population.
Conclusion: This study highlighted the exigency for screening prescriptions of cerebrovascular accident patients for potential drug-drug interactions (pDDIs). Brain edema and seizure were the most accountable complications identified in the study population. The early detection of these problems can improve stroke outcomes and can reduce the mortality or disability rate.
ASSESSMENT AND COMPARISON OF INJECTION TECHNIQUES USING MANNEQUIN AS A LEARNING TOOL AND OSPE AS AN EVALUATION METHOD
Authors: PANIGRAHY SARITA , PANDEY SUNIL KUMAR , SHEENA MEHER , SUNDARI BALA TRIPURA
Published: November 2021

Objective: The aim of the current study was to compare the effectiveness of only demonstration and demonstration coupled with the powerpoint method (intervention) in acquiring the knowledge of injection technique using objective structured practical examination (OSPE) as an evaluation tool.
Methods: The present study was conducted among IInd professional medical undergraduates (N=80). Identification of medical devices, parts of a syringe and intravenous (IV) infusion set, intramuscular (IM) injection and intravenous infusion techniques were taught using demonstration and intervention method. Participants were then evaluated for their knowledge by OSPE method using validated checklists. Participants were also asked to give feedback for the teaching and evaluation method. Data were analyzed using SPSS 20.0.0, IBM Corporation.
Results: After the intervention method 100% participant could identify needle, cannula, and IV infusion set. Noticeable difference was found in identifying parts of a syringe and IV infusion set after intervention method. OSPE evaluation post-intervention showed that more number of participants could perform the steps of injection correctly and in sequence. OSPE scores post-intervention differed significantly (<0.001) with demonstration method.
Conclusion: Demonstration coupled with the powerpoint teaching method was found better than the demonstration method alone. This method should be used to impart practical knowledge of injection technique.
ESTIMATION OF RESIDUAL SOLVENTS IN NETUPITANT API BY HEADSPACE GAS CHROMATOGRAPHY
Authors: GODE SUNNY GRACE , LAKSHMI G. VIJAYA
Published: November 2021

Objective: Residual solvents are undesirable components present in Active Pharmaceutical Ingredients (API), excipients, or drug products. To meet the specific quality-based requirements, the presence of these solvents in pharmaceutical products should be monitored to ensure their safety. The main objective of this work is to develop a new method for the determination of residual solvents in netupitant API by an HS-GC method with an FID detector.
Methods: An automated headspace GC method has been developed and validated for the estimation of the residual solvents-N-methyl pyrrolidine, xylene, toluene, and N, N Dimethylacetamide in netupitant API. The samples were dissolved in dimethyl sulfoxide and the equilibrium headspace gas was formed at 80 ᵒC, which was analyzed using a DB-624 column (30m*0.53 mm, 3.00 µm) with an injector and detector temperature set at 160 ᵒC and 230 ᵒC, respectively. The initial oven temperature was set at 60 ᵒC for 5 min and programmed at a rate of 10 ᵒC/min to the final temperature of 150 ᵒC, with a hold time of 5 min by maintaining the flow rate of 4.0 ml/min with a split ratio of 1:10, and total run time of 20 min. Nitrogen was used as carrier gas. The method developed was validated as per International Conference for Harmonization (ICH) guidelines for repeatability, linearity, range, ruggedness, detection limit, quantification limit, and recovery studies.
Results: The linearity range selected was 50-350µg/ml and the correlation coefficient(γ2) values for all the solvents were found to be>0.99; recovery studies values were in a range of 90-110% and %RSD values were also found to be not more than 10 for the solvents.
Conclusion: A novel, accurate, sensitive, and simple method was described for estimating residual solvents in Netupitant API by Headspace Gas Chromatography (HS-GC) coupled with a Flame Ionization Detector (FID). Excellent results have been observed for all the validated parameters with good peak resolution and lesser retention times.
TRANSFORMACIJA TRADICIONALNE IDEOLOŠKE PODELE U EVROPSKIM PARTIJSKIM SISTEMIM
Authors: Bursac Dejan
Published: November 2021

Autor analizira istorijske i tekuće promene u tradicionalnoj strukturi partijskih sistema i obrascima stranačkog takmičenja u današnjim evropskim državama. Kroz veliki deo moderne političke istorije, zapadnoevropske demokratije, a njima su se od pada socijalizma u Istočnom bloku pridružile i zemlje ostatka kontinenta, svoje političko takmičenje održavale su u okvirima ukorenjene ideološke podele na levicu i desnicu. Iako su se značenja i sadržaj tih pojmova menjali kroz istoriju, čini se da je tek u poslednjoj deceniji na sceni tektonska promena, koja se materijalizovala u potpunoj izmeni stranačke ponude i glasačkih obrazaca, te je pitanje da li uopšte možemo govoriti o tradicionalnom partijskom spektru na koji smo navikli u većini analiziranih društava: podeli u kojoj su takmičenje diktirali umereni, demohrišćanski, konzervativni ili ponegde liberalni desni centar sa jedne, i socijaldemokratska levica sa druge strane. Cilj rada je da analitički pristupi i teorijski objasni trendove promena u partijskim sistemima Evrope, koji su prisutni u dovoljnom broju država kako ne bi bili smatrani pojedinačnim incidentima zavisnim od konteksta neke zemlje, već, u najmanju ruku srednjeročnim, kontinentalnim trendom, vidljivim kako u starim, tako i u novim demokratijama Centralne i Istočne Evrope.
RASPAD ZAJEDNIČKE DRŽAVE SRBIJE I CRNE GORE
Authors: Todorovic Vladica
Published: November 2021

Zajednička država Srbije i Crne Gore, Savezna Republika Jugoslavija, formirana je 1992. a raspala se 2006. pod imenom Državna zajednica Srbija i Crna Gora. Na referendumu u Crnoj Gori 21. maja 2006. 55,5% izašlih građana Crne Gore glasalo je da Crna Gora postane nezavisna država, a 44,5% građana da Crna Gora ostane u zajedničkoj državi sa Srbijom. A samo 14. godina ranije 1. marta 1992. 95,96% izašlih građana Crne Gore je glasalo za zajedničku državu Srbije i Crne Gore. Istražili smo zašto su građani Crne Gore, 14. godina kasnije promenili stav o zajedničkoj državi Srbije i Crne Gore. Pretpostavljamo da je jedan od razloga delovanje komunizma u periodu 1945-1990. što je dovelo do promene srpskog nacionalnog identiteta kod određenog broja pravoslavaca u Crnoj Gori u crnogorski nacionalni identitet, kao i razblaženi komunizam u periodu nakon 1990. čiji protagonisti su nastavili nacionalnu crnogorsku identitetsku politiku. To svakako nije jedini razlog, tako da smo istražili i druge razloge, koji su po nama doprineli raspadu zajedničke države Srbije i Crne Gore 2006. U radu smo koristili metodu analize sadržaja i komparativnu metodu.
DRUŠTVENO ODGOVORNO POSLOVANjE I SOCIJALNA POLITIKA
Authors: Beric Jovan
Published: November 2021

Kompanije posluju u određenom društvenom okruženju, te se njihovo poslovanje mora razmatrati ne sme samo sa stanovišta ekonomskih ciljeva, već i sa aspekta posledica koje takvo poslovanje može proizvesti na društvenu i prirodnu okolinu u kojoj kompanija posluje. Drugim rečima, neophodno je da kompanije, pored ekonomskih, razmatraju i društvene i ekološke posledice svojih odluka. Stoga, socijalna politika, kao delatnost koja se bavi životnim i radnim uslovima ljudi i njihovim unapređenjem, treba više pažnje da posveti ovom konceptu. U radu je najpre sažeto predstavljen razvoj ovog koncepta, način na koji su ga različiti autori definisali i kritikovali, a potom se dovodi u vezu sa socijalnom politikom kako bi se ukazalo na značaj društveno odgovornog poslovanja kao preventivne delatnosti socijalne politike. Imajući u vidu da kompanije prevashodno koriste ovaj koncept iz vlastitih interesa, ovim radom ukazuje se na važnost uključivanja svih aktera koji bi komplementarno radili na razvoju i promociji društveno odgovornog poslovanja kako bi se podigla svest svih članova društva. Stožer takvog okupljanja treba da predstavljaju teoretičari i praktičari iz oblasti socijalne politike, jer će se posledice neodgovornog poslovanja odraziti na životne i radne uslove ljudi. Sa druge strane, društveno odgovornim poslovanjem moguće je delovati na socijalnu sigurnost ljudi i poboljšati njihovu životnu i radnu okolinu.
OD OBNOVE SRBISTIKE DO IMENA DEPARTMANA
Authors: Bojovic Dragisa
Published: November 2021

U radu su predstavljeni najznačajniji događaji i procesi u poslednjoj obnovi srbistike, koja se vezuje za ime profesora Petra Milosavljevića, kao i za druge filologe okupljene oko Pokreta za obnovu srbistike. Posebna pažnja je posvećena osnivanju Društva za obnovu srbistike u Prištini. U drugom delu rada akcenat je stavljen na razvoj nacionalne filologije (posebna na faze promena imena studijskog programa i departmana) na Filozofskom fakultetu u Nišu. Ističe se značaj ustanovljenja i postojanja imena srbistika u okviru studija srpskog jezika i književnosti na ovom fakultetu.
KONSTITUCIONALIZACIJA PREDSEDNIČKOG SISTEMA U TURSKOJ: DALJE OD DEMOKRATIJE, BLIŽE DESPOTIJI
Authors: Topalovic Milica
Published: November 2021

Prelaz sa zaštitničke demokratije u Turskoj koju karakteriše dominantna uloga vojske na delegativnu demokratiju sa izraženom funkcijom plebiscitirne izvršne vlasti, bila je prirodna i dugoočekivana posledica stogodišnjeg burnog razvoja političkog sistema. Turska verzija prezidencijalizma, uvedena 2017. godine, odlikuje se nedostatkom horizontalne odgovornosti, uspostavljanjem neograničene moći predsednika nad svim granama vlasti, rastom opšteg klijantelizma i smanjenom reprezentativnošću. Tri faktora koja su predodredila konstitucionalizaciju prezidencijalizma su nestabilnost parlamentarnog sistema, značajna uloga vojske u donošenju političkih odluka i viševekovni razvoj političke kulture jakog vođe. Rad teži da kroz istorijski osvrt na konstitucionalni razvoj koji je predodredio promenu političkog sistema Turske u predsednički, istraži kako je ovakav sistem obezbedio legitimitet, a istovremeno postao nedemokratski. Turska verzija predsedničkog sistema stvorila je hibridni i autohtoni režim despotije sa neuravnoteženom moći šefa države.
GOING BLUE FROM RED – CHINESE ENGAGEMENT IN THE UN PEACEKEEPING OPERATIONS
Authors: Popovic Slobodan , Stevic Ljiljana
Published: November 2021

This paper shall explore the reasons that triggered China to boost its security and economic influence within the United Nations Peacekeeping Operations (UNPKO) as a tool for embracing international challenges. By doing so, China is not just sharing the burden of providing international stability and achieving the UN Sustainable Development Goals, but exerting its influence in the process. Analysing the proposed subject, it will be demonstrated that China faces numerous obstacles whilst trying to insert the “Chinese characteristics” within the geopolitical order, geo-economics distribution of wealth and international security architecture. Instead of being perceived as a responsible stakeholder, China`s ambitious initiatives can, additionally, stir the China Threat Theory in the international community. This paper shall be consisted of two parts. The first part will tackle China`s growing footprint within the UNPKO from the end of the Cold War onward. The second part will explore the reasons that triggered China to swift its role within the UNPKO. Both global and domestic reasons will be analysed too.
La nueva Dirección General de Concesiones de Obras Públicas
Authors: Moraga Klenner Claudio
Published: November 2021

El artículo analiza la evolución de la institucionalidad pública chilena, que tiene a su cargo la administración del sistema de concesiones de obras públicas y la fiscalización de los concesionarios. Se verifica un deficiente desarrollo de los organismos administrativos involucrados, así como en la manera en que se establecen y reparten las funciones y atribuciones públicas. Se concluye que la Dirección General de Concesiones de Obras Públicas es un organismo con un diseño inconcluso: parece encontrarse en tránsito hacia una institución fiscalizadora o agencia reguladora.
Production and characterization of activated carbon from pineapple stubble for removal of methylene blue and surfactants.
Authors: Montenegro Quesada Diego , Montero Rambla Natalia , Hernández Chaverri Rodolfo Antonio , Méndez Arias Johanna
Published: November 2021

The objective of this work was to produce activated carbon from the agricultural waste known as pineapple stubble, and to test its effectiveness in the removal of methylene blue and surfactants. Activated carbon was prepared using ZnCl2 and H3PO4 as activating agents and impregnation ratios of 2: 1 and 4:1 between the agent (mL) and the precursor (g) were evaluated. It was also investigated the need or not of a drying stage prior to carbonization. The produced activated carbon was characterized through FT-IR spectroscopy, X-ray fluorescence, N2 physisorption analysis, elemental analysis and electron microscopy. Methylene blue adsorption tests were performed to determine the adsorption effectiveness of the different activated carbons produced. For such evaluation, a 23 factorial design was used, and statistical analysis determined that the activated carbon with the highest adsorption of methylene is produced under the following conditions: ZnCl2 as activating agent, an impregnation ratio of 4:1 and with no drying step prior to carbonization. This produced activated carbon is also effective in the adsorption of the surfactant sodium dodecyl sulfate and for the surfactants present in the gray water obtained after washing clothes with commercial detergent. In these cases, removal efficiencies above 98 % were achieved. With respect to the characteristics of this activated carbon, it was observed a surface area of ​​685.5 m2/g, a total pore volume of 0.53 cm3/g, and an average pore diameter of 3.1 nm. Results achieved in the present study demonstrate that is possible to produce effective activated carbon for the removal of methylene blue and surfactants from an agricultural waste such as pineapple stubble.
Feature Set Selection for Sentiment Analysis
Authors: Shinde Ganesh K.
Published: November 2021

Abstract: With proliferation of online blogging web sites, hundreds of thousands of text posts are generated. Using this rich information facilitate educated purchasing of objects, discovering and public developments involving more than a few merchandise in the market, discovering political inclination of societies previous to a country wide election, and many others. Considering that the final decade, Sentiment evaluation has received increased attention from many researchers as a procedure for addressing subject matters, such as the a fore mentioned ones. This paper specializes in Sentiment evaluation and use of sentiment Features. In this paper we have created the feature set and given input to svm and result verified for sentiment. Keywords: Sentiment analysis, support vector machine, maximum entropy, with features, without features, artificial intelligence.
Operational Parametric Based Reliability Estimation & Justification of Failure Criterion of Hydro Power Plant: A Case Study
Authors: Kanvagiya Dinesh
Published: November 2021

Abstract: Generating more Power are complex at cheaper cost, also continuous energy supplied are important Hydro power generation is one of the most successful renewable energy resources for the production electrical energy without any environmental hazard and presently it providing more than 86% of all electricity generated by renewable sources worldwide and accounts for about 20% of world electricity. To increase the percentage of green energy in account of world electricity generation the analysis must be performed to get the information about the working conditions of each component in plants so that the required maintenance action should be taken. Maintenance and operation of a hydro power plant is very complicated and the process to calculate and analyzing its compatibility and reliability is very important. In this work introducing a Markov model to evaluate the reliability parameter of THPS-I Sirmour, Rewa. For this work the operational data regarding failure and maintenance time taken to repaired and analysis of all parts of generating unit of the power plant for period of 2010-2015 is considered. The availability and reliability of individual unit of power plant is evaluated by taking into account different reliability Parameters, namely failure rate (λ), repair rate (µ), MTTR, MTTF, MTBF through the collected data and tabulating the required information for the analysis. By this analysis work we can improve reliability of all the components of each unit of power plant. The sub-unit that is commonly failed during operation is like- penstock, butter fly valve, spiral case, turbine, generator, excitation system, speed governor etc. Reliability plays a key role in the cost-effectiveness of systems Keywords: Hydro power plant, Reliability evaluation, Reliability parameters, Markov analysis, Total schedule outage hrs and Total forced outage hrs.
Imperfect Debugging in Software Systems by SRGM with TEF
Authors: Swetha K.
Published: November 2021

Abstract: In the Proposed work we are going to assimilate two important process called TEF and imperfect debugging in software systems for analyzing FDP and FCP. Byapplying the tools called debuggers we are going to identify the failures and going to correct them in order to attain the high quality reliability. As we know, testingeffort function is predicted during this time by allocating the resources which influences considerably only for the fault identification rate and also for the correction of such faults. Additionally, new faults may be included for evaluating as the feedback. In this technique, first it is proposed to demonstrate for the inclusion of TEF and fault introduction into FDP and later develop FCP as delayedFDP with a proper effort for correction. The FCP as well FCP as paired specific models which are extracted based on the basis of types of assumptions of introducing fault introduction as well as correction effort. In addition, the optimal policy of software releasefor different criteria with examples was also presentedin this work. Keywords: FDP, FCP, TEF, Fault
Prevalência de violência entre alunos nas escolas públicas do Piauí, Brasil
Authors: Barros da Silva Ellery Henrique , Negreiros Fauston , Couto Ricardo Neves
Published: November 2021

O presente trabalho tem como objetivos identificar a prevalência de violência na perspectiva do aluno, reunindo evidências de validade fatorial e precisão do questionário de violência nas escolas públicas no Piauí, no Brasil; compara, também, as pontuações quanto ao sexo dos participantes. Trata-se de um estudo do tipo documental, de abordagem quantitativa. Os documentos de registros das 21 GRE somaram 57.906. Após a coleta, foi possível analisar a estrutura fatorial das perguntas referentes ao questionário de violência por meio de uma análise de frequência, seguida de uma análise fatorial exploratória, de uma análise paralela de confiabilidade e teste t para comparação em relação ao sexo. Os resultados sugerem uma estrutura interna do questionário unifatorial, com índices psicométricos satisfatórios, além de indicarem que dentre as violências mais frequentes estavam a violência verbal, seguidas da violência moral, violência material e violência social. Quanto aos participantes, o sexo masculino obteve a maior pontuação em expressões de violência na escola.
Sensibilidad estacional en población de altas latitudes y su relación con variables de adaptación y estilo de organización temporal del trabajo
Authors: Gueichatureo Asencio Iben , Loezar Tillería Felipe , Mellado Quiroz Viviana , Vera Vega Carlos , Jelincic Vasquez Camila , Nuñez Espinoza Cristian , Estrada Goic Claudia
Published: November 2021

El trabajo estudió la frecuencia de sensibilidad estacional en una muestra de población austral chilena, alta latitud sur y su relación con actividades laborales desarrolladas en diferentes turnos de trabajo y con variables de adaptación general. Un total de 465 personas participaron respondiendo instrumentos midiendo estacionalidad (SPAQ), felicidad subjetiva (Escala de Oxford), adaptación social (Bell) y ansiedad y depresión (MASQE30). Los resultados principales indican que la frecuencia de sensibilidad estacional es alta, su nivel declarado en promedio es moderado, en su límite superior, y es evaluada como de impacto negativo significativo en la vida diaria. Respecto de los patrones estacionales, el más numeroso fue el de verano, que indica que las personas perciben beneficios con el aumento de luz, lo que correlaciona negativamente con la felicidad. Los análisis según turno de trabajo mostraron perfiles diferenciales para cada uno. Se discuten estos resultados en torno a su importancia para el desarrollo de políticas públicas asociadas a la salud física y mental de poblaciones australes.
La disrupción de lo presencial a lo virtual. Percepciones de los directores de docencia sobre el uso de plataformas digitales en contexto de pandemia en una universidad del norte de Chile
Authors: Rivera Olguin Patricio , Sánchez Espinoza Eugenio , Cortés Díaz Beatriz
Published: November 2021

Producto de la pandemia de COVID-19, la práctica educativa en los distintos niveles del sistema se vio alterada y sometida a una situación de contingencia que obligó a los docentes a usar herramientas tecnológicas y estrategias para la enseñanza en un contexto de virtualidad. El presente estudio tiene como finalidad describir el paso de una docencia presencial a una educación remota de emergencia y las dificultades que presentó esto para los académicos de la Universidad Arturo Prat (UNAP) de Chile, en cuanto al uso de las tecnologías disponibles para el desarrollo de las actividades lectivas en el contexto de la pandemia. Se desarrolla una investigación de carácter cualitativo, para caracterizar la disposición y problemáticas que evidenciaron los académicos frente a la enseñanza remota, a través de las percepciones de los directores de docencia. Los resultados muestran que los académicos han trasladado el formato de sus clases presenciales a la virtualidad, generando con ello la aplicación de un nuevo formato docente en modalidad remota. Asimismo, se demuestra un uso diferenciado de las tecnologías digitales disponibles según los tramos de edad de los docentes.
Dialogue of Religions as Dialogue of Cultures
Authors: Gainutdin R. I.
Published: November 2021

The article is devoted to the problem of dialogue between religions, which is associated with a wider range of issues as (cor)relations between religions, society and the state. The author concentrates on the case of the Russian Federation, while his paper deals with such issues as how to define subjects of interreligious dialogue, as well as which are its main traits and topics. As intermediate conclusions it could be marked that: (1) the discussion on theological issues and challenges should never be considered as a pretext for mutual rejection; (2) dialectics of tradition and renewal has to be a key topic of conversation; (3) each investigation of ethical issues must take in account the task of prevention of youth extremism, which can probably emerge in some contexts; (4) challenges of progress affect not only religious institutions but also societies as whole.
El problema de la obligación política y el principio de fair play: una evaluación crítica
Authors: Magoja Eduardo Esteban
Published: November 2021

Existen distintas teorías que buscan dar una respuesta satisfactoria a la pregunta acerca de por qué las personas deben obedecer el derecho. Una de estas propuestas es el principio de fairplay (o fairness), el cual establece que si un individuo que forma parte de un esquema social de cooperación se beneficia del esfuerzo de los demás participantes tiene el deber de soportar las cargas, pues de lo contrario cometería una injusticia. Varios autores han reconocido el valor del principio, pero otros han demostrado con buenos argumentos que tiene muchas dificultades para justificar un deber de obediencia general en esquemas complejos como el Estado. El objetivo principal de este trabajo es evaluar, mediante una metodología caracterizada por la revisión de la literatura especializada, las virtudes y debilidades del principio de fairplay como teoría de la obligación política. La conclusión obtenida es que esta teoría podría ser una propuesta adecuada siempre y cuando se satisfagan determinados requisitos.
Instituciones de desequilibrio prestacional contenidas en los principios Unidroit aplicables a los negocios jurídicos nacionales
Authors: Beltrán Valencia Gustavo Adolfo
Published: November 2021

El presente artículo tiene por objeto analizar la viabilidad jurídica de la aplicación de las instituciones jurídicas que velan por la justicia contractual en los negocios jurídicos nacionales dada la deficiente regulación que nuestro sistema legal privado posee frente a estas circunstancias de inequidad prestacional. Se analizan instituciones como la excesiva desproporción y la excesiva onerosidad (hardship), reguladas en instrumentos pertenecientes a la lex mercatoria o derecho comercial internacional, particularmente en los principios Unidroit. Para el cumplimiento de este objetivo se realiza un estudio comparativo entre las instituciones que velan por la justicia contractual contenidas en los principios Unidroit y las contenidas en el derecho positivo privado colombiano. Además, se hace un estudio de diversos casos abordados por la justicia arbitral nacional e internacional, así como por la jurisprudencia ordinaria, frente a la posibilidad de complementación e integración de las normas de los principios Unidroit en las legislaciones nacionales.Todo lo anterior para concluir que es jurídicamente viable, a través del sistema de fuentes comercial  doméstico y de los propósitos que el preámbulo de los principios Unidroit expresamente consagran, la aplicación directa a los negocios jurídicos comerciales nacionales de las figuras de la excesiva desproporción y de la excesiva onerosidad contenidas en este instrumento de derecho uniforme.
Lucha política en Twitter del ciberespacio. Partidos políticos en Perú (2019-2020)
Authors: Aliaga Lodtmann Cluber Fernando
Published: November 2021

El objetivo del presente trabajo fue conocer la forma en que se desarrolló la lucha política en la red social Twitter del ciberespacio desde junio de 2019 hasta junio de 2020. En este contexto, se determinó el nivel de adhesión de la población, la eficacidad en el logro de nuevos seguidores, el nivel de producción informativa, la efectividad, el tipo de los mensajes difundidos, los objetivos aparentes, las temáticas más recurrentes, las alianzas deducidas y el mapa de conflictividad de los partidos políticos. Se parte de una breve revisión de la teoría y de investigaciones previas relacionadas. Los resultados muestran un desarrollo asimétrico, irregular y nada homogéneo de la lucha de los partidos políticos peruanos. Se identifican las principales características de la lucha política en el ciberespacio en el Perú mediante el empleo de la red social Twitter por diez de los veinticuatro partidos políticos inscritos ante el JNE en junio de 2019. De diez partidos seleccionados cuatro no han registrado actividad comunicativa (PAP, AP, SP y PPC); dos, poca actividad (FP y PM); dos, mediana actividad (PNP y FA); y dos, alta actividad (APP y C). El PNP y FP son los que más confrontan, en tanto que la mayoría trata de evitar el antagonismo evidente, y PM evita críticas o comentarios contra partidos o líderes políticos.
Capitalismo de vigilância e tecnopolítica: os direitos fundamentais de privacidade e liberdade de expressão sob ataque
Authors: Sampaio José Adércio Leite , Furbino Marques Meire Aparecida , Bocchino Lavínia Assis
Published: November 2021

Discorre-se, no presente artigo, sobre as ameaças que as empresas de tecnologia da informação podem apresentar aos direitos fundamentais e ao constitucionalismo, diante da captura de dados, por particulares, com fins monetários, sem resposta contundente do poder estatal. Ressalta-se a vulnerabilidade das pessoas e a influência comportamental levada a efeito por meio de algoritmos e outros mecanismos ligados à internet. Aborda-se, com base em pesquisa documental, bibliográfica e normativa, o ‘capitalismo de vigilância’, proposto por Shoshana Zuboff, a garantia da privacidade e a transparência das empresas. Identifica-se um modo novo de acumulação de capital e a inadequação dos mecanismos tradicionais de regulamentação para combater seus excessos. Ao final, aponta-se para a necessidade de uma educação digital efetiva como solução à manipulação digital e combate à vulnerabilidade dos usuários - e de seus direitos.
La revolución hermenéutica como horizonte de integración científica: relación con el derecho y su historia
Authors: Menco González Eduardo , Bechara Llanos Abraham
Published: November 2021

El objetivo principal de este artículo es evidenciar los alcances de la revolución hermenéutica en el mundo contemporáneo como una nueva racionalidad de carácter interpretativo. Como elementos metodológicos para su concreción, tenemos la utilización del método histórico a partir del estudio de sus elementos tradicionales, el cual puso en entredicho la llamada racionalidad científica surgida a partir de los siglos XVII y XVIII. Como resultados de este trabajo presentamos las nuevas formas de comprensión del derecho y la ciencia jurídica, que están inmersas en la teoría de los sistemas jurídicos y de los modelos de aplicación del derecho en tiempos de Estado constitucional en la apertura del concepto de derecho en el siglo XXI a nuevas realidades y contextos jurídicos. Se concluye que la racionalidad hermenéutica es, para el derecho y otras perspectivas del conocimiento, un horizonte de interdisciplinariedad válido y necesario.
Revolución 4.0: nuevas competencias requeridas en estudiantes de educación superior para migrar a la educación 4.0
Authors: Lima Hernández Zuyin Ch.
Published: November 2021

El presente es un informe parcial del estudio sobre las competencias que debe tener los estudiantes de educación superior para migrar a la educación 4.0, a través de este se hace un primer acercamiento teórico a la realidad de la revolución 4.0, las características de las organizaciones inteligentes y la evolución que debe tener la educación superior para formar profesionales integrales para las nuevas demandas del mercado laboral. Se presenta un marco teórico general sobre cómo se da en esencia la revolución 4.0, y cómo esto debe afectar la educación tradicional para evolucionar a nuevos paradigmas, generando nuevas demandas para el docente y su práctica pedagógica, esencialmente para el estudiante universitario y
The role of coalition parties and local government expenditure: Evidence from the developing country
Authors: Rizky Harumi Puspa , Setiawan Doddy , Winarna Jaka
Published: November 2021

This study aims at examining the role of coalition parties on local government expenditure. The coalition parties are comprised of several parties that support the regional head in the local government. Specifically, this study focuses on two important aspects of local government expenditure: education and health expenditure. The research question of the study is “Does the coalition parties have a significant effect on the local government expenditure?”. The independent variable of the study is coalition parties that support elected regional heads. The dependent variable is local government expenditure, which consists of education and health expenditures. The sample of the study was the local government in the Republic of Indonesia from the 2016–2018 period. There are 632 observations as the sample of the study. The results revealed that coalition parties have a negative effect on education and health expenditure. The higher percentage of coalition parties has decreased the local government expenditure on both education and health expenditures. The result of the study shows that coalition parties have a significant effect on the local government expenditure. This study confirms Lewis and Hendrawan’s (2019) argument that coalition parties have used their discretion to influence the regional heads’ decisions on the local government expenditure
Experimental assessment for the thermal performance of scrap tire blocks as external wall insulators
Authors: Hashem Alaa Liaq , Farhood Husam Jasim
Published: November 2021

In this paper, the advantage of reusing scrap tires in Scrap Rubber
Block (SRB) to improve thermal insulation in buildings was examined
experimentally. By testing the use of SRB in black and white colours as
external wall insulators and comparing their performance with walls
without insulation. The results indicated that a wall with scrap tire
blocks gave the best thermal insulation results when the outer face was
painted white. The decrement factor (f) and the rate of heat loss
increase, while the rate of heat gain decreases. This was done through
the mechanisms of heat transfer by conduction through the layers of the
wall and the effect of adding the rubber block on its thermal
properties. The results showed that the use of rubber blocks reduces the
temperature of the inner surface of the wall by 3-4oC lower than the
traditional wall. The thermal diffusion inside the wall was determined
effectively in the case of a wall with the rubber block, where the
temperature of the inner surface reaches its maximum value by about
0.5-hour difference from the traditional wall in the case of the wall
with the rubber block in black colour, and 9.5-hour in the case with the
white block.
Study on energy and information-entropic measures of Hulthén potential in D dimension by an intuitive approximation to centrifugal term
Authors: Nath D , Roy Amlan
Published: November 2021

Energy spectrum as well as various information theoretic measures are considered for Hulthén potential in D dimension.
For a given ℓ≠0 state, analytic expressions are derived, following a simple intuitive approximation for accurate representation of
centrifugal term, within the conventional Nikiforov-Uvarov method. This is derived from a linear combination of two widely
used Greene-Aldrich and Pekeris-type approximations. Energy, wave function, normalization constant, expectation value in r and p
space, Heisenberg uncertainty relation, entropic moment of order α¯, Shannon entropy, Rényi entropy, disequilibrium, majorization as
well as four selected complexity measures like LMC (López-Ruiz, Mancini, Calbert), shape Rényi complexity, Generalized Rényi
complexity and Rényi complexity ratio are offered for different screening parameters (δ). The effective potential is
described quite satisfactorily throughout the whole domain. Obtained results are compared with theoretical energies available in literature,
which shows excellent agreement. Performance of six different approximations to centrifugal term is critically discussed. An approximate
analytical expression for critical screening for a specific state in arbitrary dimension is offered. Additionally, some inter-dimensional
degeneracy occurring in two states, at different dimension for a particular δ is also uncovered.

PACS: 02.60.-x, 03.65.Ca, 03.65.Ge, 03.65.-w Keywords: Hulthén potential, Rényi complexity ratio, Statistical complexity, Majorization, Pekeris approximation, Greene-Aldrich
approximation.
“Smell improvement by anti-IgE and anti-IL 5 biologics in patients with CRSwNP and severe asthma– A real life study”
Authors: Barroso Blanca , Valverde Marcela , Alobid Isam , JM Olaguibel , Prado Manuel Rial , Quirce Santiago , Arismendi Ebymar , Barranco Pilar , Betancor Diana , BOBOLEA IRINA , Cárdaba Blanca , Cruz Maria-Jesús , Curto Elena , Domínguez-Ortega Javier , González-Barcala Francisco-Javier , Rivera Carlos Martinez , Mahillo Ignacio , Muñoz Xavier , Picado César , Plaza Vicente , Rodrigo-Muñoz Jose , Retes Lorena Soto , Valero Antonio , POZO VICTORIA DEL , Mullol Joaquim , Sastre Joaquin
Published: November 2021

Background. Chronic rhinosinusitis with nasal polyps (CRSwNP),
characterized by partial (hyposmia) or total (anosmia) loss of smell, is
commonly associated with asthma and/or nonsteroidal anti-inflammatory
drug-exacerbated respiratory disease (N-ERD), worsens disease severity
and quality of life. The objective of this study was to determine
whether, in real-life conditions, biological treatments prescribed for
severe asthma can improve olfaction in patients with CRSwNP. A further
objective was to compare smell improvement in N-ERD and non-N-ERD
subgroups. Methods. A multicenter, non-interventional,
retrospective, observational study was performed, including 206 patients
with severe asthma undergoing biological treatment (omalizumab,
mepolizumab, benralizumab, or reslizumab) with CRSwNP. Results.
Improved olfaction was found after treatment with all monoclonal
antibodies: omalizumab (35.8%), mepolizumab (35.4%), reslizumab
(35.7%), and benralizumab (39.1%), with no differences between groups.
Patients with atopy, greater use of short course systemic
corticosteroids, and larger polyp size were more likely to experience
improvement in smell. The proportion of patients experiencing smell
improvement was similar between the N-ERD (37%) and non-N-ERD (35.7%)
groups. Conclusions. This is the first study to compare
real-life improvement in sense of smell among patients undergoing
long-term treatment with omalizumab, mepolizumab, reslizumab, or
benralizumab for severe asthma and associated CRSwNP. Approximately 4
out of 10 patients reported a subjective improvement in sense of smell
(with non-significant differences between biologic drugs). No
differences were found in smell improvement between the N-ERD and
non-N-ERD group.
Narrativas de experiencias pedagógicas
Authors: Rios Jane Adriana
Published: November 2021

El texto se centra en la discusión sobre la narrativa como territorio de (re)existencias docentes, fundadora de otros saberes y pedagogías en la vida cotidiana de la escuela. La discusión parte de la idea de construir redes de formación a partir de principios que inscriben los saberes de la experiencia en el proceso de narrar la vida-profesión desde la horizontalidad, alteridad, inclusión y autoría docente. El trabajo se realizó desde los enfoques epistemopolíticos con la Documentación Narrativa de la Experiencia Pedagógica a partir de los estudios realizados por Suárez (2007) y, sobre todo, por la búsqueda de otras epistemologías (Santos, 2010) que se inscriben en narrativas de (re)existencias. Es una investigación narrativa con profesores de Educación El texto se centra en la discusión sobre la narrativa como territorio de (re)existencias docentes, fundadora de otros saberes y pedagogías en la vida cotidiana de la escuela. La discusión parte de la idea de construir redes de formación a partir de principios que inscriben los saberes de la experiencia en el proceso de narrar la vida-profesión desde la horizontalidad, alteridad, inclusión y autoría docente. El trabajo se realizó desde los enfoques epistemopolíticos con la Documentación Narrativa de la Experiencia Pedagógica a partir de los estudios realizados por Suárez (2007) y, sobre todo, por la búsqueda de otras epistemologías (Santos, 2010) que se inscriben en narrativas de (re)existencias. Es una investigación narrativa con profesores de Educación Básica en Bahía/Brasil. El texto dialoga con los procesos de construcción de las narrativas de experiencias pedagógicas en redes de formación a partir de las aproximaciones con las teorizaciones de Santos sobre las ecologías del conocimiento, las traducciones interculturales y la artesanía de la práctica que entrelazan la construcción de otra política del conocimiento.
Relatos de Susana y Alicia
Authors: Porta Luis Gabriel , Ramallo Francisco
Published: November 2021

Entre lo biográfico, lo autobiográfico y lo íntimo la fragilidad de la condición humana se desprende la autonomía, la libertad y el individualismo del sujeto soberano que caracterizó al modelo clásico del conocimiento. Al calor de la pandemia del COVID-19, en este texto recuperamos los fundamentos de la narrativa, la cual es vista como un flujo que devela nuestra frágil condición epistémica (inter)dependiente. Identificaremos, a partir de dos registros narrativos performáticos, las maneras en las que lo autobiográfico y lo íntimo yuxtaponen el proyecto con utopías y alianzas (inter)especistas. Finalmente haremos un reconocimiento de las mociones que revitalizan la condición indivisible del ser en el contexto de la investigación en el área de la educación y la potencia estética de la vida narrada como modo de ser, estar, sentir y desear el mundo, los mundos posibles.
Organización del saber en el mundo de vida de artistas docentes
Authors: Serrano Castañeda José Antonio , Tavira Gómez Raúl , Ramos Morales Juan Mario
Published: November 2021

Con apoyo en la entrevista, como vía regía en la perspectiva biográfico-narrativa, el presente texto bordea la configuración de artistas que despliegan el capital profesional adquirido con fines de participación en la docencia y la formación de nuevas generaciones de profesionales en el ámbito artístico. Primero, tomamos como derrotero la noción de saber, como efecto de la estructuración del capital cultural, social y profesional, para describir el recorrido efectuado por los tres participantes del estudio y a fin de definir las coordenadas que orientan la labor de los artistas docentes. Más adelante, exponemos el valor y la influencia de las relaciones familiares en la disposición que evidencian los individuos para asumir una determinada trayectoria, a pesar de la trayectoria de toda persona es un recorrido individual, un camino único irrepetible. En la descripción del camino recorrido se valora el tiempo empleado en la incorporación de las habilidades propias del ámbito artístico que lleva a la distinción de cada uno de los integrantes del núcleo familiar. De igual forma, damos cuenta del sentido que tiene ser docentes en el ámbito artístico, los deseos y orientaciones que los colocan como sujetos activos en un campo social determinado. Cerramos el texto con reflexiones alrededor de lo contingente de la acción social: pertenencia a un grupo social, las tomas de posición y la adopción de proyectos en la configuración del agente particular