bluuebunny/crossref_metadata_2025 huggingface dataset:
Knowledge about menstrual cup and its usage among medical students
Authors: Eti Manorama , S. Shreya M. , A. Sailakshmi M. P.
Published: November 2019

Background: Menstrual cups have been available for decades, but their use in India is limited because of lack of awareness and popularity of sanitary pads. Since they are reusable, they reduce solid waste and are environment friendly. The need of the hour is education, awareness, and availability of the eco-friendly practices when it comes to managing menstrual waste effectively. Once that is taken care of, it will be easy for anyone to make a green switch.Methods: A total 400 medical undergraduate students (females) were given a questionnaire. The objective of the study was to assess knowledge about the menstrual cup among students.Results: Among 400 medical students, 28(7%) of them dint know what a menstrual cup was! 262(70.4%) students were for usage of menstrual cup in virgins. There was no clear picture among students regarding material used in cup manufacture, its emptying time and sterilisation technique. Among 372 students, none of them used a menstrual cup.Conclusions: All the students in the study used sanitary pads, owing to its popularity and promotion. There was lack of awareness about the cup. So, we conclude that menstrual cup needs promotion in India. To boost the adoption rate of menstrual cups, youth should be targeted, who are more open to the idea of environment-friendly products. The Government must conduct awareness programs in the rural areas and work constantly spreading the message across all socio-economic sectors so that we can make the dream of a “pad free country”, a reality soon.
Cerebroumbilical doppler ratio in pregnancy induced hypertension and its prediction for adverse perinatal outcome
Authors: Salvi Meena Bhati
Published: November 2019

Background: To compare the changes in pulsatility index (PI) values of fetal middle cerebral artery (MCA), umbilical artery (UA) and ratio of PI of MCA and UA (cerebroumbilical ratio, C/U ratio) in normal pregnancies with pregnancy induced hypertension (PIH) and to evaluate their usefulness for predicting adverse perinatal outcome.Methods: This was a prospective comparative study carried out over a period of 1 year on total 140 patients between 30-40 weeks of gestation. Study group comprised of 70 patients with PIH. The control group comprised of 70 patients with normal BP. Both the groups were followed by doppler ultrasound and the UA PI, the MCA PI and the C/U ratio were measured. The results of the last doppler ultrasound before delivery were considered in the correlation with various adverse perinatal outcome. Sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of MCA PI and UA PI and C/U ratio were calculated and compared for predicting adverse perinatal outcome.Results: Abnormal C/U ratio was more common in PIH group (42.85%) than control group (5.71%). In the study group, 83.33% patients of abnormal C/U ratio showed adverse perinatal outcome. C/U ratio had highest sensitivity (75.75%), negative predictive value (80%) and diagnostic accuracy (81.42%) compared to MCA PI and UA PI for predicting adverse perinatal outcome in PIH women.Conclusions: Incidence of adverse perinatal outcome was more common with abnormal C/U ratio. C/U ratio is better predictor for adverse perinatal outcome in PIH women than individual MCA PI and UA PI.
Successful management of a near miss case of eclampsia with intracranial haemorrhage requiring craniotomy
Authors: Kaundinya Aditi P. , Satia Meena N. , Badhwar V. R.
Published: November 2019

Large population-based studies on stroke report that intracerebral haemorrhage is rare in young women however it is a grave and disturbing complication of pregnancy. Preeclampsia is usually clinically silent, but may cause symptoms of neurological dysfunction such as headache, visual disturbances and impairment of consciousness. Eclampsia is in the occurrence of seizures in the context of preeclampsia and is often, but not always, preceded by the above neurological symptoms. Most published data support the view that preeclampsia and eclampsia are important causative factors for pregnancy related ICH. Sparse data is available with respect to the management of such cases. Identification of near miss cases is an important step in reducing mortality. Herein we report a near miss case of eclampsia with intracranial haemorrhage requiring craniotomy.
Pregnancy with chronic myeloid leukemia: case report and literature review
Authors: Chowdhury Tanzeem Sabina , Jereen Israt , Chowdhury T. A.
Published: November 2019

Chronic myeloid leukemia (CML) is a rare condition during reproductive age. Still, women may present with pre-existing or newly diagnosed CML during pregnancy. The management of chronic myeloid leukemia during pregnancy requires balancing the well-being of the mother with that of fetus. Tyrosine Kinase inhibitors are considered the most effective drug against CML but they are still not considered safe during pregnancy and breast feeding. So, there is a need for management of CML with alternate drugs during pregnancy. Here we report a case of a 26-year-old lady who was diagnosed with chronic myelogenous leukemia (CML) at 20 weeks of gestation and had an atypical chromosome translocation t (9:22). She was managed jointly by obstetrician and haemato-oncologist for the remainder of her pregnancy and eventually she delivered a healthy baby at term.
Successful live birth after heterotopic ruptured cornual pregnancy with twin intrauterine gestation in an in vitro fertilization conception
Authors: Bansal Venus , Chhabra Muskaan , Chopra Rahul , Prajapati Pooja
Published: November 2019

Heterotopic pregnancies, especially in the cornual region which were a rarity till recent times, have become a more common occurrence due to increasing practice of assisted reproduction. Optimal management of such cases is imperative to manage the risk of hypotension and shock in case of rupture and to judiciously preserve the intrauterine pregnancy. Here we are reporting a case of IVF conception of twin intrauterine pregnancy with a cornual heterotopic pregnancy. Patient presented to the emergency department with features of acute abdomen, haemoperitoneum and shock. Ultrasound findings were suggestive of rupture of cornual heterotopic pregnancy, 1500 ml haemoperitoneum with live twin intrauterine gestation. Patient was resuscitated with iv fluids blood transfusion. Immediate laparotomy was done and cornual site repaired and covered with an omental patch while preserving the intrauterine gestations. Thereafter, pregnancy was carefully monitored with a high index of suspicion for rupture of site of cornual repair with advancing gestational age. Patient was readmitted at 24 weeks with pain abdomen and cornual site was found to be 4mm in thickness. She was managed conservatively till 27 weeks when she had preterm rupture of membranes and emergency LSCS was done. She delivered healthy twin male babies, 780 gmb and 795 gm respectively. This case demonstrates that cornual heterotopic pregnancy is a diagnosis which may be easily missed and can present as a life-threatening complication if it ruptures and significant intraperitoneal bleeding occurs. However, it is possible to successfully manage these cases with timely intervention, proper uterine reconstruction and monitoring of intrauterine gestation.
A near miss case of placenta percreta in a patient with post myomectomy scar
Authors: Singh Vinita , Sahu Rajshree , Das Esha , C. Pavan B.
Published: November 2019

The term placenta accreta or placenta accrete syndrome is used to describe a spectrum of an abnormal placental implantation and firm adherence which are classified according to the depth of invasion into the uterus. A 28-year-old elderly primigravida presented AIIMS OPD to for the 1st time at 13+2 weeks of gestation with brownish discharge per vaginum. Ultrasonography done showed 12 weeks single intrauterine pregnancy with subchorionic haemorrhage of 3.7×2.52 cm with placenta being fundoanterior. She underwent myomectomy 2 years back and during her antenatal care in 3rd trimester growth scan at 30+2 weeks of gestation placenta was fundoanterior with loss of retroplacental hypoechoic in the upper margin of placenta at the myomectomy scar site with small extra uterine collection seen measuring 7.6×2.3 cm and hence possibility of placenta accreta was suggestive by the above findings confirmed by MRI. Emergency cesarean section done at 36+6 weeks of gestation for leaking per vaginum. Manual removal of placenta was tried but it failed and soon atonic PPH developed. Seeing no response with uterotonics internal iliac artery ligation was also attempted but failed. Immediate decision for hysterectomy was taken as a life-saving method. On adhesiolysis in the fundal region placental tissue perforating uterine serosa was visible on the surface of uterus, hence diagnosis of placenta percreta was confirmed which was further confirmed on histopathological report. Currently hysterectomy or local resection is preferred over conservative management with methotrexate.
Evaluation of factors influencing hypertension among adults of South Karnataka
Authors: H. S. Darshan Kumar , Sasalu Karthik N. , R. Suresh S.
Published: November 2019

Background: Studies have shown that BP is an independent risk factor for CVD. This relationship is independent as well as consistent and continuous. Observations involving more than 1 million individuals have shown that death from both CVD and stroke increases progressively and linearly from BP levels of as low as 115mm systolic and 75 mm diastolic upwards. The increased risks are present in all age groups ranging from 40 to 89 years old. Hence the present study was undertaken to evaluate the factors influencing hypertension among Adults.Methods: In the present study 400 patients both out-patient and in-patients attending Adichuchanagiri Institute of Medical Sciences were evaluated for factors influencing Hypertension and other cardiovascular diseases. The 400 patients were divided into 200 cases who were again divided into categories based on severity of hypertension into stage 1 and stage 2 and duration of <5 years and ≥5 years.Results: A positive correlation was found between the severity of hypertension, the patients who were found to be having stage 2 hypertension had an increase in SUA levels which was statistically significant when compared with those with stage 1 hypertension. Conclusions: With the results based on the study carried out author concluded that there is direct relation between hyperuricemia and hypertension. Also, the study showed that the SUA levels were significantly increased in patients with Stage 2 hypertension as compared with those of stage 1 hypertension, showing that the severity of hypertension also related to the SUA levels.
The study of correlation between Body Mass Index and glycemic control-HbA1c in diabetes type 2 patients
Authors: Sisodia Rakesh K. , Chouhan Mahendra
Published: November 2019

Background: Obesity has major adverse effects on health. Obesity is associated with an increase in mortality, with a 50-100% increased risk of death from all causes compared to normal-weight individuals, mostly due to cardiovascular causes. The aim of this study was to correlate Body Mass Index (BMI) and glycaemic control (HbA1c) in type 2 Diabetic patients.Methods: In this study 100 patients of type 2 diabetic were subjected to detailed history, clinical examination, BMI, HbA1c and routine biochemical investigations.Results: Out of 100 diabetic patients included in this study 62 of them were male and 38 were female. Among 100 patients. Majority of patients were overweight (BMI 25-29.9) which is account to about 58 of total cases, 30 patients were normal BMI and 12 patients were obese. Statistical analysis a positive correlation found between BMI and poor glycaemic control (HbA1c), which is significant.Conclusions: From this study it was concluded that obesity (BMI) is associated with poor glycaemic control.
A comparative study of intrathecal bupivacaine and levobupivacaine for patients undergoing caesarean section
Authors: Kaur Kiranpreet , Johar Sanjay , Kumar Anil , Jain Mamta , Kumar Prashant , Singh Anish
Published: November 2019

Background: The present study was conducted to compare the effects of 0.5% isobaric levobupivacaine and 0.5% hyperbaric bupivacaine in pregnant females undergoing caesarean section.Methods: Study was conducted on 100 pregnant females undergoing caesarean section. They were randomly divided into two groups B and L receiving 2 ml of 0.5% hyperbaric bupivacaine and 0.5% levobupivacaine respectively. Two groups were compared with regard to sensory block, motor block, haemodynamic stability and complications if any.Results: Time to achieve sensory blockade till T6 dermatome was prolonged in group B (162.52±80.55 sec) as compared to group L (139.40±49.79 seconds) (p value= 0.087). Prolonged duration of motor blockade was observed in group B (160.76±6.56 minutes) as compared to group L (131.48±14.42 minutes) (p<0.001). Less haemodynamic stability was seen in patients of group B with more incidence of hypotension and bradycardia.as compared to group L.Conclusions: Levobupivacaine is nearly equally effective to bupivacaine to produce sensory and motor blockade with comparable onset time and better haemodynamic stability with lesser side effects.
Study of nonalcoholic fatty liver Telangana population
Authors: Patel Parth N. , Mohiuddin Mohd Ifthekhar
Published: November 2019

Background: Among 83 patients of both sexes aged between 25 to 65 adults had NAFLD with metabolic syndrome were studied.Methods: U.S.G. biochemical study included total cholesterol, AST, ALP, S, Albumin total Bilirubin, FBS, HbA1c and blood pressure was recorded.Results: Among 16(19.2%) had grade-I (mild steatosis) 38(45.7%) had grade-II (Moderate steatosis), 29(34.9%) had grade-III (severe steatosis), The clinical manifestation were 49(59%) had BMI 22.8 to 23.2, 34(40.9%) had BMI 23.3 to 24.2. D.M status was 33(39.7%) were pre-diabetic, 50(60.2%) were diabetic mellitus. 19(22.8%) were norma- tensive, 64(77.1%) were hypertensive, 63(75.9%) were hyperlipidemic, 23(27.7%) had IHD. 4(4.81%) had MI. Mean value of total cholesterol was 223±9.2, Triglyceride 24.8±13.3, HDL 42.3±2.5, LDL 128±13.8, AST 52.8±3.6, ALT 67.2±6.8, ALP 107±11.8, S. Albumin 3.50±0.12, Total bilirubin 0.93±0.10, FBS 13.±12.2, HB A/c 9.10±402.Conclusions: The present study of NAFLD was performed by combination of radiological and laboratory techniques, greatly reducing the requirement for invasive biopsy and reduce the morbidity and mortality.
Drug resistance profile among multi-drug resistant tuberculosis patients at diagnosis and correlation with history of anti-tubercular treatment in a tertiary care center
Authors: Kumar Rahul , Garg Rajiv , Kshetrimayum Silpa , Jain Amita
Published: November 2019

Background: Drug Resistant Tuberculosis (DR-TB) is a major threat to the realization of the goal of a TB free world in the near future. It is important to study the reasons for the increasing number of such cases so that effective action can be taken to control this growing epidemic.Methods: Sputum from 36 patients diagnosed with acquired pulmonary Multidrug Resistant Tuberculosis (MDR-TB) were subjected to first- and second-line Drug Sensitivity Testing (DST) after liquid culture in mycobacterium growth Indicator Tube (MGIT). Primary MDR-TB cases were excluded. The relation of the drug sensitivity profile with the history of prior treatment taken was statistically analysed.Results: Majority of the patients had received appropriate treatment, and most had adhered to prescribed treatment. Among the 36 patients, 24(66.7%) were found to be Pre-Extensively Drug Resistant (Pre-XDR-TB) and 4(11.1%) were extensively drug resistant XDR-TB cases. Inappropriate prescription of fluoroquinolone (FQ) was found to be most common. Prior intake of any drug was not found to significantly affect subsequent resistance to that drug.Conclusions: Fluoroquinolone resistance is quite common in patients with DR-TB (66.7%). This study did not find the prior use of FQ or any other drug to significantly affect subsequent resistance to the drug. Primary drug resistance is thus a major concern. 11.1% patients were found to be XDR-TB cases. Hence DST for first- and second-line drugs should be done at the time of diagnosis to avoid failure of treatment with a predesigned regimen.
Studies on oligosaccharyl transferase in yeast.
Authors: Lennarz William J
Published: November 2019

In yeast, OT consists of nine different subunits, all of which contain one or more predicted transmembrane segments. In yeast, five of these proteins are encoded by essential genes, Swp1p, Wbp1p, Ost2p, Ost1p and Stt3p. Four others are not essential Ost3p, Ost4p, Ost5p, Ost6p. All yeast OT subunits have been cloned and sequenced (Kelleher et al., 1992; 2003; Kelleher & Gilmore, 1997; Kumar et al., 1994; 1995; Breuer & Bause, 1995) and the structure of one of them, Ost4p, has been solved by NMR (Zubkov et al., 2004). Very recently, the preliminary crystal structure of the lumenal domain of an archaeal Stt3p homolog has been reported (Mayumi et al., 2007). Homologs of all OT subunits have been identified in higher eukaryotic organisms (Kelleher et al., 1992; 2003; Kumar et al., 1994; Kelleher & Gilmore, 1997).
Distinct role of clathrin-mediated endocytosis in the functional uptake of cholera toxin.
Authors: Broeck Davy Vanden , Lagrou Albert R , De Wolf Marc Js
Published: November 2019

The involvement of the clathrin-mediated endocytic internalization route in the uptake of cholera toxin (CT) was investigated using different cell lines, including the human intestinal Caco-2 and T84 cell lines, green monkey Vero cells, SH-SY5Y neuroblastoma cells and Madin-Darby canine kidney cells. Suppression of the clathrin-mediated endocytic pathway by classical biochemical procedures, like intracellular acidification and potassium depletion, inhibited cholera toxin uptake by up to about 50% as well as its ability to raise intracellular levels of cAMP. Also prior exposure of these cell types to the cationic amphiphilic drug chlorpromazine reduced the functional uptake of cholera toxin, even to a greater extent. These effects were dose- and cell type-dependent, suggesting an involvement of clathrin-mediated endocytosis in the functional uptake of cholera toxin. For a more straightforward approach to study the role of the clathrin-mediated uptake in the internalization of cholera toxin, a Caco-2(eps-) cell line was exploited. These Caco-2(eps-) cells constitutively suppress the expression of epsin, an essential accessory protein of clathrin-mediated endocytosis, thereby selectively blocking this internalization route. CT uptake was found to be reduced by over 60% in Caco-2(eps-) paralleled by a diminished ability of CT to raise the level of cAMP. The data presented suggest that the clathrin-mediated uptake route fulfils an important role in the functional internalization of cholera toxin in several cell types.
Effect of N-glycosylation inhibition on the synthesis and processing of classical swine fever virus glycoproteins.
Authors: Tyborowska Jolanta , Zdunek Ewa , Szewczyk Bogusław
Published: November 2019

Classical swine fever virus (CSFV) is often used as a surrogate model in molecular studies of the closely related hepatitis C virus. In this report we have examined the effect of the inhibition of glycosylation on the survival and maturation of CSFV. Viral glycoproteins (E(rns), E1, E2) form biologically active complexes - homo- and heterodimers, which are indispensable for viral life cycle. Those complexes are highly N-glycosylated. We studied the influence of N-glycosylation on dimer formation using E(rns) and E2 glycoproteins produced in insect cells after infection with recombinant baculoviruses. The glycoproteins were efficiently synthesized in insect cells, had similar molecular masses and formed dimers like their natural counterparts. Surprisingly, the addition of tunicamycin (an antibiotic which blocks early steps of glycosylation) to insect cell culture blocked not only dimer formation but it also led to an almost complete disappearance of E2 even in monomeric form. Tunicamycin did not exert a similar effect on the synthesis and formation of E(rns) dimers; the dimers were still formed, which suggests that E(rns) glycan chains are not necessary for dimer formation. We have also found that very low doses of tunicamycin (much lower than those used for blocking N-glycosylation) drastically reduced CSFV spread in SK6 (swine kidney) cell culture and the virus yield. These facts indicate that N-glycosylation inhibitors structurally similar to tunicamycin may be potential therapeutics for the inhibition of the spread of CSFV and related viruses.
Limitation of usage of PicoGreen dye in quantitative assays of double-stranded DNA in the presence of intercalating compounds.
Authors: Koba Marcin , Szostek Alicja , Konopa Jerzy
Published: November 2019

PicoGreen is a very sensitive fluorescent dye for quantitative assays of double-stranded DNA (dsDNA) in solution and is used in several analytical protocols in which sensitive and precise DNA detection is needed, also for examination of drug-DNA interactions. The data shown in this paper indicate that compounds intercalating to DNA influence the applicability of PicoGreen dye for quantitative measurements of dsDNA, and for this reason PicoGreen dye is not suitable for examination of drug-DNA interactions, especially interstrand DNA crosslinks.
Bacterial DNA repair genes and their eukaryotic homologues: 2. Role of bacterial mutator gene homologues in human disease. Overview of nucleotide pool sanitization and mismatch repair systems.
Authors: Arczewska Katarzyna D , Kuśmierek Jarosław T
Published: November 2019

Since the discovery of the first E. coli mutator gene, mutT, most of the mutations inducing elevated spontaneous mutation rates could be clearly attributed to defects in DNA repair. MutT turned out to be a pyrophosphohydrolase hydrolyzing 8-oxodGTP, thus preventing its incorporation into DNA and suppresing the occurrence of spontaneous AT-->CG transversions. Most of the bacterial mutator genes appeared to be evolutionarily conserved, and scientists were continuously searching for contribution of DNA repair deficiency in human diseases, especially carcinogenesis. Yet a human MutT homologue--hMTH1 protein--was found to be overexpressed rather than inactivated in many human diseases, including cancer. The interest in DNA repair contribution to human diseases exploded with the observation that germline mutations in mismatch repair (MMR) genes predispose to hereditary non-polyposis colorectal cancer (HNPCC). Despite our continuously growing knowledge about DNA repair we still do not fully understand how the mutator phenotype contributes to specific forms of human diseases.
Amyloid beta enhances cytosolic phospholipase A2 level and arachidonic acid release via nitric oxide in APP-transfected PC12 cells.
Authors: Chalimoniuk Małgorzata , Stolecka Anna , Cakała Magdalena , Hauptmann Susane , Schulz Kris , Lipka Uta , Leuner Kristine , Eckert Anne , Muller Walter E , Strosznajder Joanna B
Published: November 2019

Cytosolic phospholipase A2 (cPLA2) preferentially liberates arachidonic acid (AA), which is known to be elevated in Alzheimer's disease (AD). The aim of this study was to investigate the possible relationship between enhanced nitric oxide (NO) generation observed in AD and cPLA2 protein level, phosphorylation, and AA release in rat pheochromocytoma cell lines (PC12) differing in amyloid beta secretion. PC12 control cells, PC12 cells bearing the Swedish double mutation in amyloid beta precursor protein (APPsw), and PC12 cells transfected with human APP (APPwt) were used. The transfected APPwt and APPsw PC12 cells showed an about 2.8- and 4.8-fold increase of amyloid beta (Abeta) secretion comparing to control PC12 cells. An increase of NO synthase activity, cGMP and free radical levels in APPsw and APPwt PC12 cells was observed. cPLA2 protein level was higher in APPsw and APPwt PC12 cells comparing to PC12 cells. Moreover, phosphorylated cPLA2 protein level and [3H]AA release were also higher in APP-transfected PC12 cells than in the control PC12 cells. An NO donor, sodium nitroprusside, stimulated [3H]AA release from prelabeled cells. The highest NO-induced AA release was observed in control PC12 cells, the effect in the other cell lines being statistically insignificant. Inhibition of cPLA2 by AACOCF3 significantly decreased the AA release. Inhibitors of nNOS and gamma-secretase reduced AA release in APPsw and APPwt PC12 cells. The basal cytosolic [Ca2+](i) and mitochondrial Ca2+ concentration was not changed in all investigated cell lines. Stimulation with thapsigargin increased the cytosolic and mitochondrial Ca2+ level, activated NOS and stimulated AA release in APP-transfected PC12 cells. These results indicate that Abeta peptides enhance the protein level and phosphorylation of cPLA2 and AA release by the NO signaling pathway.
Root canal morphology. Endodontic access
Authors: Григорьев Сергей , Griroriev Sergey , Сорокоумова Дина , Sorokoumova Dina , Чернышева Нина , Chernyshova Nina , Чагай Андрей , Chagay Andrey , Епишова Анна , Yepishova Anna
Published: November 2019

The training manual is developed in full accordance with the training program for doctors -
dentists.
The manual presents classifications of the types of root canal structure, features
morphology of root canals in various groups of teeth, principles of creating endodontic access, classification of tools for creating access and principles of their use. The presentation form and numerous illustrations make this publication informative and useful in clinical practice.
This manual is intended to provide methodological assistance to students of the Faculty of Dentistry, residents and practicing dentists.
Comparación de la calidad embrionaria entre fertilización in vitro (FIV) y cultivo intravaginal de ovocitos (INVO) en el Centro Colombiano de Fertilidad y Esterilidad - CECOLFES, Bogotá, Colombia
Authors: Navarro-Carbonell Doris Elena , Pulido-Torres Carlos , Saa-Madriñan Ángela María , Lucena-Quevedo Elkin
Published: November 2019

Objetivo: comparar la calidad embrionaria y describir las tasas de implantación, embarazo y aborto en las técnicas de fertilización in vitro (FIV) y el cultivo intravaginal de ovocitos.Materiales y métodos: cohortes históricas de pacientes con tratamiento de fertilización in vitro y el cultivo intravaginal de ovocitos en el Centro Colombiano de Fertilidad y Esterilidad (Cecolfes) durante el año 2010. Se incluyeron 137 pacientes aspiradas dentro de los cuatro grupos de estudio: Grupo 1, FIV/Incubadora; Grupo 2, FIV/INVO; Grupo 3, ICSI/INVO, y Grupo 4, ICSI/Incubadora. Se midió el peso de la paciente, el número de ovocitos recuperados y óvulos maduros (MII), la tasa de implantación y la tasa de embarazo y aborto en cada uno de los grupos. Se realizó análisis mediante la prueba de Kruskal-Wallis; la calidad embrionaria fue evaluada con un análisis de covarianza multivariado (MANOVA).Resultados: se observó diferencia significativa en la calidad embrionaria entre las dos técnicas FIV e INVO (p = 0,0388). En la técnica INVO se presentaron mayores tasas de división embrionaria (µ = 7,35/INVO frente a 6,64/Incubadora) y menor fragmentación (µ = 4,67/INVO frente a 4,59/ Incubadora). En cuanto a la tasa de implantación, embarazo y aborto se obtuvieron más altos porcentajes en los grupos INVO.Conclusión: la técnica INVO se asoció a mejor calidad embrionaria. Las tasas de implantación, embarazo y bajas tasas de aborto son semejantes a las descritas en la técnica FIV.
¿Por qué la endometriosis infiltrativa profunda debe ser considerada una entidad diferente a la endometriosis peritoneal?
Authors: De Los Ríos-Posada José Fernando
Published: November 2019

El presente artículo de revisión recopila, expresa, demuestra y analiza información científica que permite concluir con claridad que la endometriosis infiltrativa profunda es una entidad nosológica diferente en múltiples aspectos fisiopatológicos, diagnósticos y terapéuticos a la endometriosis peritoneal.Fue presentado, discutido y avalado por el Consenso Colombiano de Expertos en Endometriosis llevado a cabo dentro del marco del XXVIII Congreso Colombiano de Obstetricia y Ginecología en mayo de 2012.Pretende ser un documento de consulta y de soporte bibliográfico y legal que brinde claridad a los actores del sistema de salud colombiano y al público en general sobre las obvias diferencias que existen entre las dos enfermedades.
Rehabilitation Counselor Educators' Experiences of Social Injustice and Social Justice Infusion
Authors: Dong ShengLi , Ethridge Glacia , Rodgers-Bonaccorsy Roe
Published: November 2019

This study examined the types of social injustice experiences rehabilitation counselor educators reported, and the relationship between different levels of social injustice experiences and infusion strategies of social justice into the curricula. The participants in the study included 101 rehabilitation counselor educators recruited from the listserv of the National Council on Rehabilitation Education. A quantitative content analysis method was used. The findings showed that social injustice experiences reported by the participants tend to be multidimensional. Participants who reported a high level of exposure to social injustice experiences were more likely to infuse social justice into their curricula at a higher level than participants who reported a low level of exposure to social injustice experiences. The study revealed that gaining an understanding of social injustice in educators' personal and professional lives may foster their efforts to integrate social justice into the curricula, which in turn, may potentially enhance the social justice competency for trainees. Implications for research and practice were discussed.
HIV Microaggressions Across Bronfenbrenner's Ecological Systems: A Social Justice Perspective
Authors: Manyam Suneetha , Panjwani Shama , Parker John Mark
Published: November 2019

Microaggressions play a prominent role in the cultural competency of the rehabilitation professionals. Understanding these biases and stereotypes faced by the individuals living with HIV/AIDS from a social justice and systemic perspective is crucial to become a culturally competent rehabilitation counselor. The current article is a systematic review of the anecdotal and scientific literature from 1900 to 2017 about these microaggressions toward individuals with HIV/AIDS. Authors present the common themes that emerged out of this extensive qualitative analysis by utilizing the Urie Bronfenbrenner's ecological model as a basis and discuss its impact from a social justice perspective. Implications for rehabilitation counselors and future recommendations are presented at the end.
Perbandingan Algoritma Genetika dengan Algoritma Greedy Untuk Pencarian Rute Terpendek
Authors: Oktaviandi Rizky Berlia , Hadi M. Sadid Tafsirul , Santoso Alanfansyah Ghozy , Maidah Nova El
Published: November 2019

In everyday life we ​​often travel from place to place. So that we need to consider the time and cost efficient. Therefore, accuracy is needed to determine the shortest path as a consideration in decision to show the path to be taken. The results obtained also require speed and accuracy with the help of a computer. Using or functioning a computer there must be a distributed program in it. The programs contained in the computer vary widely and each program must use an algorithm. Algorithm is a collection of commands to solve a problem gradually from start to finish. There are various algorithms that can be used to find the shortest route such as Breadth First Search algorithm, Depth First Search, A *, Hill Climbing and others. For that required comparison algorithm which is able to find the shortest route accurately and efficiently. In this journal, the algorithm to be compared is the genetic algorithm and greedy algorithm to find the shortest route on a map. Some aspects to be compared are aspects of the accuracy, speed, and complexity of genetic algorithms and greedy algorithms for the shortest route search.
Traitor Tracing Schemes: a Review
Authors: Prihandoko Antonius Cahya
Published: November 2019

This paper provides a review on traitor tracing schemes that are developed to counter piracy strategies. The review starts with a formal definition of the traitor tracing schemes. The paper is then outlined based on two main strategies which may taken by digital content pirates. Mostly the pirates have strategy to make use leaked decryption key or leaked decrypted content. For each piracy strategy, we presents traitor tracing schemes that can be used to counter the piracy. We also analysis strength and weakness of each group of the schemes. At the end of this paper, we propose to combine some schemes for better protection.
Sistem Pakar Untuk Menentukan Status Pertumbuhan Pada Anak Menggunakan Inferensi Fuzzy (Sugeno)
Authors: Agustina Emi , Purnomo Agus Sidiq
Published: November 2019

The detection of child growth should be done as early and as accurately as possible, so that if there is a deviation of child growth can be known earlier and can be found a solution to the deviation. In the examination of children who performed in pharmacies depok sleman pengelolahan data inspection done manually so that data is not well recorded, it causes the data is lost and not clear. For that we need a system capable of data menguin so as to minimize the things that are not desirable. In this study, the researchers aimed to create an expert system that gives an idea of the growth in children with fuzzy logic motede which requires several variables, namely age, height, gender and weight which will be taken z-score weight and z- Score height. Based on the test result which has been done with 85 examination data of children, it can be concluded that the implementation of fuzzy sugeno method can be used as a determination of the status of the child's growth with total accuracy of 81.18%.
The Implementation of Minimum Forest Graph for Centroid Updating Process on K-Means Algorithm
Authors: Maududie Achmad , Wibowo Wahyu Catur
Published: November 2019

K-Means is a well known algorithms of clusteing. It generates some groups based on degree of similarity. Simplicity of implementation, ease of interpretation, adaptability to sparse data, linear complexity, speed of convergence, and versatile in almost every aspect are noble characteristics of this algorithm. However, this algorithm is very sensitive on defining initial centroids process. Giving a bad initial centroid always produces a bad quality output. Due to this weakness, it is recommended to make some runs with different initial centroids and select the initial centroid that produces cluster with minimum error. However, this procedure is hard to achieve a satisfying result.

This paper introduces a new approach to minimize the initial centroid problem of K-Means algorithm. This approach focus on centroid updating stage in K-Means algorithm by applying minimum forest graph to produce better new centroids. Based on gain information and Dunn index values, this approach provided a better result than Forgy method when this approach tested on both well distributed and noisy dataset. Moreover, from the experiments with two dimentional data, the proposed approach produced consisten members of each cluster in every run, where it could not be found in Forgy method.
Implementasi Pelayanan Administrasi Kependudukan Desa Kalimanah Wetan Purbalingga Berbasis Online
Authors: Radiyah Ummu , Setyowati Dheska Ranita , Anton Anton
Published: November 2019

Implementation of Population Administration Services in the Village of Kalimanah Wetan Purbalingga is still done manually. In the processing of data population is still conventional with a data collection system that is now felt there are still many shortcomings that occur, because the existing system still uses sheets of paper so that it can cause existing data easily lost or damaged. The system development in the form of a web-based Population Service system in Kalimanah Wetan Village is a system that provides information on population data and web- based letter printing services, so as to help speed and quality in delivering information and simplify correspondence printing services to be more effective and efficient. In this system, the web can only be accessed by users, namely citizens and administrators. The method used in developing this system is SDLC (System Development Life Cycle) with the waterfall process model. In this study, besides describing the theoretical study that is used as the basis of the preparation, it will also be discussed regarding system design and the making of Population Services web. So that it is expected to be implemented in a product that will correct any shortcomings in the old system.
The Branding of Jember Tape Chips Products Through Audio Visual Ads
Authors: Aji Fajar , Haryanto Dwi
Published: November 2019

Jember is a district with the geographical conditions of mountains, agriculture, and plantations. The connection between these three characteristics gave birth to a diversity of arts, languages, tourism, and culinary. Utilization of the agricultural sector, especially in the Ajung sub-district, there are people in this area who rely heavily on natural resources, especially in agricultural and plantation resources. This beneficial natural potential makes the people in Ajung Subdistrict, especially in Pancakarya Village, much to build a home industry for processing agricultural products in the form of tape industry. The problem faced by partners is the lack of familiarity of products that are widely owned, thus causing the partner's economy to not be optimal. This problem is the basis of the service program proposed by the proponent to strive to increase the marketing of tape chips. Based on the specific targets to be achieved, the main purpose of the community service activities proposed is to strengthen the brand image of the chips product through audio-visual advertising. The method of implementing this service program is adjusted to the standard operating procedure for making audiovisual works consisting of stages: 1) pre-production consisting of idea-finding, planning, and preparation; 2) production; and 3) post-production. The results of audio-visual advertising of tape chips are expected to be a promotional media for products owned by Koplak Food Homemade Industry so that they can be widely known to the public and build brand image products for tape chips.
Pemberdayaan Pusat Kesehatan Pesantren (Poskestren) Untuk Meningkatkan Perilaku Hidup Bersih Dan Sehat
Authors: Rif'ah Erwin Nur
Published: November 2019

Pondok pesantren dikenal sebagai suatu lembaga pendidikan Islam tertua di Indonesia. Banyaknya jumlah pesantren di Jember, serta besarnya jumlah santri pada tiap pesantren menjadikan lembaga ini memiliki kontribusi yang besar dalam pembangunan. Berdasarkan hasil penelitian sebelumya ditemukan bahwa masalah yang sering dihadapi pesantren adalah rendahnya kesadaran berperilaku hidup bersih dan sehat. Akibatnya banyak santri yang mengalami sakit dan tinggi penularan penyakit infeksi di kalangan santri. Edukasi dasar-dasar PHBS kepada para santri diharapkan dapat meningkatkan nilai pengetahuan santri terkait urgensi dari implmentasi PHBS. Pembentukan dan pelatihan Kader Santri Sehat juga diharapkan mampu menjadi salah satu upaya meningkatkan lifeskill hidup sehat bagi santri untuk hidup sehat secara mandiri sekaligus menjaga kestabilan kualitas lingkungan sehat di pesantren yang akan dibentuk. Inisiasi dan pendampingan pembentukan Poskestren di kedua pesantren juga dilakukan guna menciptakan suatu sistem manajemen kesehatan terpadu dan terstruktur di lingkungan pondok pesantren. Sehingga harapan pengasuh pondok pesanten untuk meningkatkan mutu bekal keterampilan santri dapat tercapai. Solusi dalam peningkatan pengetahuan terkait PHBS di kedua pondok pesantren akan dilaksanakan melalui beberapa metode, antara lain: 1) Pembekalan atau alih teknologi; yaitu penyadaran dengan memberikan informasi dan keterampilan pada penghuni pondok pesantren tentang dasar-dasar, manfaat, dan urgensi PHBS komunitas di lingkungan pondok pesantren; 2) Pendampingan; yaitu melalui pendampingan terhadap pondok pesantren dalam membentuk Poskestren; 3) Pelatihan manajemen dan pembentukan Kader Santri Sehat; yaitu memberikan pengetahuan tentang pengelolaan dan pembangunan relasi kerja untuk Poskestren, serta melakukan pelatihan bagi Kader Santri Sehat sebagai investasi keberlanjutan program Poskestren yang telah didirikan. Partisipasi mitra dilakukan mulai tahap persiapan hingga pengelolaan Poskestren yang terbentuk. Partisipasi mitra dievaluasi pada setiap kegiatan, sehingga diharapkan pada saat akhir kegiatan, keberlanjutan program dapat tetap berjalan.

Kata kunci: Pondok Pesantren, Sangria, Poskestren, PHBS.
An Investigation on Utilization of Internet and Television in Senior Secondary Schools in Rigachukun Inspectorate of Kaduna State in Nigeria
Authors: Fadele Oluwaseyi , Haruna S , Amusan Temiloluwa , Oluwmuyiwa Samsom , Onwuegbunam Nancy
Published: November 2019

An investigation was carried out to study the effects of television and internet on academic performance of senior secondary schools students in Rigachukun Inspectorate of Kaduna state. A well structured and designed questionnaire was adopted in eliciting information from the respondents. The respondents were sampled from schools within Kaduna state. The information obtained showed that the percentage of senior secondary school students who made use of internet for academic purpose was as much as those who could not operate a computer or even browse the internet. Good number of students applied internet mostly through phones and computer with internet access in solving their assignment. A larger percentage of students devoted their time to watching non-educative programs on television, even though it was discovered that some of them also watch educative programs. Positive impacts of television and internet are however obscuring and not glaring. Investigation carried out revealed that students in senior secondary schools need to be sensitized and oriented on how they can derive the best from internet and television. Schools should be encouraged in using television and internet as an instrument of learning and teaching.
Development of a Current Sensor with Broad Current Measurement Range Using High- and Low-Range Parts
Authors: shin JungWon , Kang Shinwon , Kim SaeWan
Published: November 2019

The measurement range of a conventional current sensor is narrow because it is used with signals relative to the rated values of the measurement range from a voltage-type device. Consequently, multiple current sensors must be used in accordance with the measurement range. To address this problem, this paper proposes a new current sensor with a clamp-shaped part for low current measurement and a simple straight structure for high current measurement. The output signals of the proposed current sensor are amplified with a Hall element using the magnetic force of a rectangular air gap inside the clamp. To verify the characteristics of the proposed current sensor, a current was applied to an external load, and the value determined by the current sensor noted. Then, electromagnetic field analysis was performed through current sensor modeling and the results obtained compared to the actual sensor results. The proposed sensor had a 1% linearity in the output signals and exhibited dynamic characteristics over a wide current range.
On a simulation of soot formation under diffusion combustion of hydrocarbon fuels
Authors: Galanin Mikhail Pavlovich , Isaev Alexander Vasilievich , Konev Stanislav Andreevich
Published: November 2019

An approach to mathematical modeling of soot particles formation and particles growth under diffusion combustion of hydrocarbon fuel is presented. The process is described with a chain of carbon transitions between different selected states. The stiff system of Kolmogorov ordinary differential equations (ODEs) is used to simulate the process. The solution of the system represents the probability of carbon presence in the selected states.
Efektifitas Cuka Kayu sebagai Pestisida Nabati dalam Pengendalian Hama Crocidolomia Pavonana dan Zat Perangsang Tumbuh pada Sawi
Authors: Ambarwati Nunung , Subagiya Subagiya , NS YV Pardjo
Published: November 2019

Cabbage caterpillar pests (Crocidolomia pavonana) is one of the main obstacles inhibiting the production both in quality and quantity. Control is generally done with chemical pesticides that can harm the environment and humans. Wood vinegar is an agricultural waste that is used to increase the quantity and quality of mustard plant. This study aims to determine the effectiveness of wood vinegar as a botanical pesticide in the mustard plant and the PGR and the most effective concentration. Research using completely randomized design with 7 degree treatment laboratory tests (mortality, biology, kemampua eating) and 8 standard treatment field test (the intensity of pest attack, plant height, leaf number and weight of mustard plant), repeated 3 times. The results showed that wood vinegar is not effective as a pesticide plant pest control C.pavonana the mustard. Wood vinegar speed up the life cycle C. pavonana. Wood Vinegar can help to enhance and augment leaf mustard plant so that it can be effective as an aphrodisiac mustard plant grows. The greater the concentration of a given wood vinegar, increased growth (both height and number of leaves of mustard plant).
Budidaya Selada pada Vertikultur Hidroponik Sistem Karpet
Authors: Pamungkas Hanggoro Sabdo , Putri Retno Bandriyati Arni , Muliawati Endang Setia
Published: November 2019

The limitation of land area that for fulfillment of food savety needs to be resolved immediately. One of the things that can be done, is the use technology of verticulture system without soil media. Pouch system use the carpet is one verticulture system that can be applied. Basically, carpet is capable of holding water and has a high capillarity, so it can be used as a media pit as conductor of nutrients to the substrat medium. This study aimed to evaluate the hydroponic verticulture of carpet system on lettuce cultivation. This study was conducted in August 2013 to October 2013 at the Greenhouse B, Faculty of Agriculture, University of Sebelas Maret Surakarta. The treatments was arranged based on the completely randomized design (CRD) used factorial with 2 factor consists of 4 level and one control. Each treatment was repeated 3 times. Based on the efficiency use of nutrients and electric cost, the result showed that vertical cross pattern and 15 minutes fertigation treatments gave best results.