bluuebunny/crossref_metadata_2025 huggingface dataset:
Health Risk Assessment Based on Exposure to Chemicals in Air
Authors: Sakamoto Hironari , Uchiyama Shigehisa , Sato Ayana , Isobe Tomohiko , Kunugita Naoki , Ogura Hironao , Nakayama Shoji
Published: November 2022

Few studies have investigated personal exposure concentrations of not only some volatile organic compounds but also more types of chemicals including acidic gases and acrolein. We measured the personal exposure concentrations of 35 chemicals including these chemicals in indoor and outdoor air in Chiba-shi, Japan, for 7 days in summer and winter to assess the associated health risks in 22 people. The personal exposure concentrations of nitrogen dioxide were higher in winter than in summer, and those of formaldehyde, p-dichlorobenzene, and tetradecane were higher in summer than in winter. The personal exposure concentrations were mostly equal to or lower than the concentrations in indoor air, contrary to the results of a lot of previous studies. The high-risk chemicals based on personal exposure concentrations were identified as acrolein (max. 0.43 μg/m3), benzene (max. 3.1 μg/m3), and hexane (max. 220 μg/m3) in summer, and acrolein (max. 0.31 μg/m3), nitrogen dioxide (max. 320 μg/m3), benzene (max. 5.2 μg/m3), formic acid (max. 70 μg/m3), and hexane (max. 290 μg/m3) in winter. In addition, we estimated personal exposure concentrations according to the time spent at home and the chemical concentrations in indoor and outdoor air. We found that the estimated concentrations of some participants largely differed from the measured ones indicating that it is difficult to estimate personal exposure concentrations based on only these data.
The Importance of Research on Occupational Sedentary Behaviour and Activity Right Now
Authors: Clark Bronwyn K. , Brakenridge Charlotte L. , Healy Genevieve N.
Published: November 2022

The workplace has been identified as a key setting for public health interventions to ‘promote and maintain the highest degree of physical, mental and social well-being of workers in all occupations’ by the World Health Organisation [...]
The Role of Midwives in the Course of Natural Childbirth—Analysis of Sociodemographic and Psychosocial Factors—A Cross-Sectional Study
Authors: Guzewicz Patrycja , Sierakowska Matylda
Published: November 2022

Background: An important role in the course of natural childbirth is played by midwives, who should effectively work on relieving pain. This study aims to present the opinions of midwives on non-pharmacological methods of relieving labor pain; the frequency of their use and reasons for their abandonment; and the relationship between the use of non-pharmacological methods of relieving labor pain and perceived job satisfaction, burnout, and self-efficacy of the midwife. Methods: The study was conducted online, with the participation of 135 Polish midwives working in the delivery room. The author’s survey questionnaire, the Generalized Self-Efficacy Scale (GSES), the LBQ Burnout Questionnaire, and the Scale of Job Satisfaction were used. Results: Among the surveyed midwives, 77% use vertical positions in work with a patient giving birth. Almost all respondents consider vertical positions as an example of a non-pharmacological method of relieving labor pain; those with master’s degree felt more prepared for their use (p = 0.02). The most common reason for abandoning their use was disagreement on the part of co-workers (p = 0.005). An association was observed between the use of vertical positions and the level of burnout (p = 0.001) and a significant correlation between preparation for their use and self-efficacy assessment, burnout, and job satisfaction. Conclusion: Our research shows that it would be important to conduct additional training on the use of non-pharmacological methods to relieve labor pain and to present their benefits. In contrast to other research results, our results showed that midwives feel well prepared to use these methods; however, similar to other research, we found that they often feel disagreement from colleagues and a lack of support from their leaders. The use of vertical positions is related to burnout.
Effects of Problem-Based Learning Strategies on Undergraduate Nursing Students’ Self-Evaluation of Their Core Competencies: A Longitudinal Cohort Study
Authors: Lu Yen-Chiao Angel , Lee Shu-Hsin , Hsu Ming-Yi , Shih Fen-Fen , Yen Wen-Jiuan , Huang Cheng-Yi , Li Pei-Ching , Hung Ching-Yen , Chuang Hsiao-Ling , Kuo Ching-Pyng
Published: November 2022

To respond to patients’ increasing demands and strengthen nursing professionals’ capabilities, nursing students are expected to develop problem-solving skills before they enter the workforce. Problem-based learning (PBL) is expected to provide effective simulation scenarios and realistic clinical conditions to help students achieve those learning goals. This article aims to explore the effects of PBL strategies on nursing students’ self-evaluation of core competencies. This longitudinal cohort survey study evaluated 322 nursing students attending Chung Shan Medical University, Taiwan, in 2013 and 2014, where PBL teaching strategies are used in all four undergraduate years from freshman to senior. Based on their undergraduate academic levels, students were categorized into three groups- one-year PBL exposure, two-year PBL exposure, and three-year exposure. A core competency questionnaire was administered twice to ask participants to self-assess five professional competencies: learning attitude, problem identification, information analysis, execution, and life-long learning. The results showed that students with the longest exposure to PBL (Group 3) had higher self-evaluated scores for all core competencies than the other groups, except for the execution competency. The mean total competency score increased by 0.12 points between the pre-and-test. In addition, the mean score increased significantly more in Group 3 than in Groups 1 and 2. These trends were consistent for the information analysis, execution, and life-long learning competencies. In conclusion, the changes in the self-evaluated scores between groups indicate PBL strategies effectively improve nursing students’ core competencies. The longest exposure group reported higher self-evaluated core competency scores than the other groups, especially for the information analysis, execution, and life-long learning competencies.
Effectiveness of an E-Book App on the Knowledge, Attitudes and Confidence of Nurses to Prevent and Care for Pressure Injury
Authors: Chuang Shu-Ting , Liao Pei-Lin , Lo Shu-Fen , Chang Ya-Ting , Hsu Hsiang-Tzu
Published: November 2022

Aims: This study evaluates the effectiveness of an interactive E-book app training program in improving nurses’ knowledge, attitudes, and confidence to prevent and care for pressure injury. Design: Randomized experimental study. Methods: Participants were recruited from a teaching hospital in Taiwan. The study was carried out between 20 March 2014 to 1 April 2016. In total, 164 participants were randomly assigned to a pressure injury E-book app training program (n = 86) or a conventional education program (n = 78) with a one-month follow-up. Outcome variables were levels of pressure injury knowledge, attitudes, and confidence of pressure injury care. Results: Participants answered 51.96% of the pressure injury knowledge questions correctly before the intervention and 75.5% after the intervention. The pressure injury attitude score was slightly positive, with moderate confidence in pressure injury care. The knowledge, attitudes, and confidence of pressure injury care of the two groups in the pretest and posttest groups increased significantly. Analysis of covariance indicated that nurses in the pressure injury E-book app group had significantly greater improvement in knowledge, attitudes, and pressure injury care confidence as compared with the control group. Conclusion: The pressure injury E-book app interactive training program was effective in improving nurses’ knowledge and attitudes toward pressure injury care and in enhancing their confidence in pressure injury care; therefore, this program has potential for nurses’ in-service education in both Taiwan and worldwide. Impact: E-book apps allow individuals to control the time and place of learning. Direct observation of procedural skills can provide feedback to trainees on techniques to ensure learning effectiveness and pressure injury care quality.
An Assessment of Vape Shop Products in California before and after Implementation of FDA and State Regulations
Authors: Galstyan Ellen , Galimov Artur , Meza Leah , Huh Jimi , Berg Carla J. , Unger Jennifer B. , Baezconde-Garbanati Lourdes , Sussman Steve
Published: November 2022

Vape shops specialize in sales of e-cigarettes and related products. This study examines whether vape shops adapted their products and services in response to changes in federal and state policies that affect the tobacco retail environment between 2014–2022. In this multicohort study, four waves of study data were used to examine the trends in products sold in vape shops in Southern California. Items sold were assessed through systematic store product observations and included categories of e-cigarettes, device modification equipment, and other products (e.g., Cannabidiol (CBD), paraphernalia). Descriptive statistics are reported. The availability of disposable devices increased from 18% at Wave 1 to 98% of shops at Wave 4. Pod mods were first observed in 79% of the shops beginning at Wave 3. Device modification drills later become obsolete, from 60% at Wave 1 to 0 by Wave 4; self-service sampling displays declined from 83% of shops to 9%. Vape shops did not carry CBD products until Wave 3 (2017/2018), when 19.0% of shops carried CBD products and 72.9% at Wave 4. Future research should examine how e-cigarette retailers and manufacturers respond to changing state and federal regulations to better understand the implications of regulatory efforts.
Body Composition Analysis in Perimenopausal Women Considering the Influence of Vitamin D, Menstruation, Sociodemographic Factors, and Stimulants Used
Authors: Kostecka Dominika , Schneider-Matyka Daria , Jurewicz Alina , Kamińska Magdalena , Barczak Katarzyna , Grochans Elżbieta
Published: November 2022

(1) The perimenopausal period and menopause are physiological stages of a woman’s life, and they may result in the occurrence of many health problems. The aim of this study was to assess the impact of sociodemographic factors related to the use of stimulants and the presence of menstruation and vitamin D concentration in women’s health based on the analysis of their body composition parameters. (2) The study was carried out among 191 women. The diagnostic poll method was used, the levels of serum vitamin D were tested, and a body composition analysis was carried out. (3) Correlations between the vitamin D serum concentration and the following factors were established: adipose tissue mass (%) (rho = −0.18; p = 0.011), visceral adipose tissue (rho = −0.18; p = 0.014), BMI (rho = −0.22; p = 0.002), muscle mass (rho = −0.19; p = 0.008), osseous tissue mass (rho = −0.18; p = 0.013), and the phase angle value (rho = −0.2; p = 0.005). A statistically significant correlation between adipose tissue mass (Mdn = 34.4 vs. 32.2; p = 0.018; η2 = 0.029), visceral adipose tissue (Mdn = 8 vs. 6; p = 0.000; η2 = 0.106), and metabolic age (Mdn = 49 vs. 42; p = 0.000; η2 = 0.098) exists. (4) The following conclusions were made: (i) Menstruating women were characterized by increased body composition parameters, especially adipose tissue mass, visceral adipose tissue, and metabolic age. Greater muscle and osseous masses were noted in regularly menstruating women. (ii) A correlation between the vitamin D concentration and body composition parameters in the studied women was observed.
Leveraging Faith Communities to Prevent Violence against Women: Lessons from the Implementation and Delivery of the Motivating Action through Empowerment (MATE) Program
Authors: Pearce Karen , Borkoles Erika , Rundle-Thiele Sharyn
Published: November 2022

Gender-based violence is a human rights and public health issue, disproportionately affecting women. The Motivating Action Through Empowerment (MATE) bystander program aims to address violence against women by shifting focus from perpetrators and victims of violence to community responsibility for not accepting attitudes and behaviors that support or allow the violence to occur. Traditionally bystander programs have been delivered through institutions, most notably college campuses in the United States. The translation of bystander programs to community settings is not widely reported. This research aimed to understand whether a violence prevention program could be effectively delivered in a faith community setting; specifically, it focuses on the implementation of MATE in a Christian church network in the Gold Coast region of Queensland, Australia. Semi-structured interviews were conducted with ten church-based trainers in the MATE pilot program. Theoretically informed analysis using the COM-B behavior model identified that environmental factors had a large bearing on opportunities to deliver MATE workshops. This research identified six key lessons for MATE and other programs wishing to leverage faith communities: (1) Provide religious context; (2) Accommodate diversity; (3) Build faith leader capacity; (4) Employ social marketing; (5) Undertake co-design; (6) Actively administer, measure and monitor.
Urban Regeneration Involving Communication between University Students and Residents: A Case Study on the Student Village Design Project
Authors: Kim Joo Young , Kim Jung Hoon
Published: November 2022

This study analyzed the effect of the application method of community planning in the case of the Student Village Design Project. Urban regeneration is a method that develops a city with the direct involvement of residents. However, in Korea, urban renewal projects are focused on external expansion, thereby generating conflicts among residents and prolonging these projects. In particular, university towns are experiencing various types of conflicts compared with other urban regeneration projects because the lives of residents and university students are overlapped. Therefore, the research method is conducted as follows to analyze the communication effect in accordance with the purpose of the study. First, we reviewed community planning methods as led by university students. Second, we applied community planning to the project. Third, the results and effects of resident communication were analyzed after applying community planning. Fourth, in the student-led urban regeneration, a community planning method that has results and effects in resident communication was derived. We found that community planning is a significant means of communication between university students and residents. The concrete finding was derived from necessary and optional methods that have high communication effects with residents among the community planning methods.
Insight into the Molecular Signature of Skeletal Muscle Characterizing Lifelong Football Players
Authors: Orrù Stefania , Imperlini Esther , Vitucci Daniela , Caterino Marianna , Mandola Annalisa , Randers Morten Bredsgaard , Schmidt Jakob Friis , Hagman Marie , Andersen Thomas Rostgaard , Krustrup Peter , Ruoppolo Margherita , Buono Pasqualina , Mancini Annamaria
Published: November 2022

Background: Aging and sedentary behavior are independent risk factors for non-communicable diseases. An active lifestyle and structured physical activity are positively associated with a healthier quality of life in the elderly. Here, we explored the proteomic/metabolomic muscular signature induced by lifelong football training associated with successful aging. Methods: The study was performed on nine lifelong football players (67.3 ± 2.8 yrs) and nine aged-matched untrained subjects. We performed a proteomic/metabolomic approach on V. lateralis muscle biopsies; the obtained data were analyzed by means of different bioinformatic tools. Results: Our results indicated that lifelong football training is able to enhance the muscles’ oxidative capacity in the elderly by promoting fatty acids as preferential energetic substrates and hence determining a healthier body composition and metabolic profile; furthermore, we showed that the total polyamine content is higher in lifelong football players’ muscle, enforcing the involvement of polyamines in muscle growth and hypertrophy. Conclusions: Lifelong football training, as a structured physical activity, significantly influences the expression of the proteins and metabolites involved in oxidative metabolism and muscle hypertrophy associated with successful aging.
Understanding Aotearoa New Zealand University Students Intentions to Seek Help If Experiencing Mental Distress: A Comparison of Naturalistic and Interventional Findings
Authors: Mason Andre , Johnstone Grace , Riordan Benjamin C. , Lie Celia , Rapsey Charlene , Treharne Gareth J. , Jang Kyungho , Collings Sunny C. , Scarf Damian
Published: November 2022

University students globally are consistently identified as a vulnerable group for mental distress and suicide. Despite this, students report low engagement in help-seeking behaviours. This series of studies aimed to assess barriers to help-seeking for students and the impact of an intervention that sought to increase support-seeking intentions. In Study 1, 373 undergraduate psychology students completed items related to depression, anxiety, suicidal ideation, stigma, and help-seeking intentions. In Study 2, 133 undergraduate psychology students were randomly allocated into one of three intervention groups (control, infographic, video) and completed measures as used in Study 1. Despite experiencing clinically relevant symptoms and recent suicidal ideation, students in Study 1 tended to report low intentionality to seek help, citing perceptions that their distress was not serious enough or a desire to handle their issues independently. In Study 2, an infographic about different support services increased student’s intentions to access support services and reduced their perception that their issues were not serious enough. Overall, Aotearoa New Zealand students endorsed similar barriers to help-seeking as students in other countries. Importantly, we demonstrated that a simple infographic intervention reduced perceptions regarding these common barriers and may increase students’ knowledge about when to seek help.
Sex Differences in the Effects of Cognitive Reappraisal Training on Conditioned Fear Responses
Authors: Liao Suqun , Xiao Wen , Wang Yancai
Published: November 2022

Sex differences in emotion regulation strategies may impact sex differences in affective disorders. Using cognitive reappraisal strategy in the discriminative task of conditioned fear was studied to understand how sex differences in emotion regulation impact on conditioned fear in men and women. College students with low cognitive reappraisal scores completed the task of conditioned fear during two days: acquisition and extinction at the first day, and re-extinction at the second day. The reappraisal training was carried out before conditioned fear task. The self-reported fear rating of the conditioned stimulus (CS) and US-expectancy in the conditioned fear (unconditioned stimulus, US) were analyzed. Results showed all subjects acquired conditional fear and successfully distinguished CS+ from CS−. Cognitive reappraisal significantly reduces the fear rating and improves the extinction of US-expectancy in both sexes, but the fear rating in female reappraisal group decreases more slowly than that in male reappraisal group, as well as the extinction of US-expectancy in woman requiring a longer time and more trials of extinction than that in men. For individuals with low cognitive reappraisal scores, cognitive reappraisal promotes the extinction of conditioned fear in both males and females. Because of the original gender difference of conditioned fear extinction and emotion regulation, the effect of cognitive reappraisal on conditioned fear is complex, which shows differently in influence speed and practice effect.
Chemical Composition of Atmospheric Air in Nemoral Scots Pine Forests and Submountainous Beech Forests: The Potential Region for the Introduction of Forest Therapy
Authors: Dudek Tomasz , Marć Mariusz , Zabiegała Bożena
Published: November 2022

Studies show that forests are one of the main recreational destinations. This can be explained by their beneficial effects on the health of their visitors, which can be attributed to compounds from the terpene group. The aim of this research was to determine the chemical composition of air in the interiors of Nemoral Scots pine forests and submountainous beech forests, with the determination of compounds of the terpene group. Samples of organic compounds present in the air were collected with the use of Tenax TA sorbent tubes. The process of separation, identification, and determination of the extracted organic compounds was carried out with the use of the gas chromatography technique integrated with a flame ionization detector. Additional identification of the extracted compounds was carried out with the use of GC coupled with mass spectrometry. The most abundant group of compounds was the aliphatic hydrocarbons, both saturated (linear and branched) and unsaturated (terpenes). Carbonyl compounds were also found in the collected samples, but they constituted no more than 10% of all compounds present on the chromatograms. The concentrations of terpenes and terpenoids in the forest atmosphere varied from 10 to 74 µg·m−3, representing on average 33% of the total volatile organic compounds.
An Exploratory Study in Non-Professional Football on the Perception of Stakeholders about the New Working Professional Profile of Sports Kinesiologist
Authors: Raiola Gaetano , D’Isanto Tiziana , D’Elia Francesca , Altavilla Gaetano
Published: November 2022

In Italy, recent amendments to Legislative Decree n. 36 of 28 February 2021, on sports work, may have made the application of the reform by stakeholders unclear, with the risk of generating further confusion among them. One of the most critical points concerns the possible equivalencies to the professional profile of the kinesiologist, which would be illegitimately recognized even for a different level of education, contrary to the requirements of the European qualification framework. The aim of the study was to understand the perceptions of stakeholders in the world of non-professional football regarding recent legislative provisions. A survey, divided into two sections, was administered to 112 presidents and 112 trainers of non-professional football associations of the province of Salerno. The first section presents five items common for both presidents and trainers, which seek to probe stakeholders’ perceptions of the enjoyment, appropriateness, usefulness, and scientificity of kinesiologists. The second section presents five differentiated items. Validity and reliability were calculated. A chi-square analysis (χ2) was performed to test the independence within and between-subjects (trainers and presidents) on their perceptions about the new working professional profile of sports kinesiologist. From the results, it was possible to appreciate a discordance of opinion among stakeholders. Although the majority of presidents and trainers are in favour of introducing such a professional profile (p < 0.05), contradictions emerge concerning the contribution the new professional profile can make in practice (p > 0.05). The perceptual contradictions found among stakeholders’ responses demonstrate how the complexity of recent regulatory provisions regarding possible equivalencies to the title of kinesiologist have inevitably generated further confusion among stakeholders.
Effects of a Structured Multicomponent Physical Exercise Intervention on Quality of Life and Biopsychosocial Health among Chilean Older Adults from the Community with Controlled Multimorbidity: A Pre–Post Design
Authors: Pizarro-Mena Rafael , Duran-Aguero Samuel , Parra-Soto Solange , Vargas-Silva Francisco , Bello-Lepe Sebastian , Fuentes-Alburquenque Mauricio
Published: November 2022

Structured multicomponent physical exercise (PE) for older adults, with a combination of strength, aerobic, flexibility, and balance exercises, has been shown to have benefits for physical, cognitive, social, and metabolic functioning, as well as counteracting chronic pathologies and geriatric syndromes. However, little is known about the effect of these interventions in Chilean older adults. Our objective was to determine the effect of a structured multicomponent PE intervention on the quality of life (QoL) and biopsychosocial factors of community-living older adults. We conducted a pre–post intervention without control group, with a face-to-face structured multicomponent PE intervention (cardiovascular, strength/power, flexibility, static and dynamic balance, other psychomotor components, and education), based on FITT-VP principles (frequency, intensity, type, time, volume, and progression of exercise), at moderate intensity, 60 min per session, three times per week, and 12 weeks in duration, among 45 persons with an average age of 70.74 years. Participants were evaluated at the beginning and end of the intervention with different instruments of comprehensive gerontological assessment (CGA). Post intervention, participants (83.70% average attendance) significantly improved scores in QoL, biological and biopsychosocial frailty, sarcopenia, functionality in basic, instrumental, and advanced activities of daily living, dynamic balance, cognitive status and mood, systolic and diastolic blood pressure, weight, body mass index, strength and flexibility clinical tests of lower and upper extremity, aerobic capacity, agility, and tandem balance. The indication and prescription of structured multicomponent PE based on FITT-VP principles, as evaluated with the CGA, improved the QoL and biopsychosocial health of older adults. This intervention could serve as a pilot for RCTs or to improve PE programs or services for older adults under the auspices of existing public policy.
The Economic Value of Water Ecology in Sponge City Construction Based on a Ternary Interactive System
Authors: Zhou Wenzhao , Wang Yufei , Wang Xi , Gao Peng , Lin Ciyun
Published: November 2022

Ecological water resources occupy a vital position in the national economy; without sufficient ecological water resources, the construction and economic development of sponge cities would be seriously restricted. Appropriately, the Chinese government proposed that sponge city planning should be carried out in accordance with the number of available ecological water resources. The government therefore put forward the method of conservation and intensification to solve the problem of water shortage. This paper highlights the interactions between ecological water resources, sponge cities, and economic development in northern China, starting with the interaction and mechanism of action that concerns ecological water resource utilization, sponge cities, and economic development. In the empirical test, the dynamic changes of the three indicators were analyzed empirically using the panel data vector autoregression method, and the dynamic relationship of each factor was measured using generalized moment estimation. It was found that ecological water resources are a key factor in promoting regional economic development, and the relationship between ecological water resources and sponge cities is both supportive and constraining; therefore, the constraints that ecological water resources place on sponge cities also indirectly affects economic development. To disconnect the use of water and ecological resources from economic development, it is necessary to note the following: the feedback effect of economic development and the resolution of the contradiction between sponge cities, water, and ecological resource use.
What Works to Improve Wellbeing? A Rapid Systematic Review of 223 Interventions Evaluated with the Warwick-Edinburgh Mental Well-Being Scales
Authors: Blodgett Joanna M. , Birch Jack M. , Musella Margherita , Harkness Frances , Kaushal Aradhna
Published: November 2022

Introduction: The Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS) is a commonly used scale of mental wellbeing focusing entirely on the positive aspect of mental health. It has been widely used in a broad range of clinical and research settings, including to evaluate if interventions, programmes or pilots improve wellbeing. We aimed to systematically review all interventions that used WEMWBS and evaluate which interventions are the most effective at improving wellbeing. Methods: Eligible populations included children and adults, with no health or age restrictions. Any intervention study was eligible if the wellbeing outcome was measured using the 7 or 14-item WEMWBS scale assessed both pre- and post-intervention. We identified eligible intervention studies using three approaches: a database search (Medline, EMBASE, CINAHL, PyschInfo and Web of Science from January 2007 to present), grey literature search, and by issuing a call for evidence. Narrative synthesis and random-effects meta-analysis of standardised mean differences in the intervention group were used to summarise intervention effects on WEMWBS score. Results: We identified 223 interventions across 209 studies, with a total of 53,834 participants across all studies. Five main themes of interventions were synthesised: psychological (n = 80); social (n = 54); arts, culture and environment (n = 29); physical health promotion (n = 18); and other (n = 28). Psychological interventions based on resilience, wellbeing or self-management techniques had the strongest effect on wellbeing. A broad range of other interventions were effective at improving mental wellbeing, including other psychological interventions such as cognitive behavioural therapy, psychoeducation and mindfulness. Medium to strong effects were also seen for person-centred support/advice (social), arts-based, parenting (social) and social prescribing interventions. However, a major limitation of the evidence was that only 75 (36%) of studies included a control group. Conclusions: WEMWBS has been widely used to assess wellbeing across a diverse range of interventions, settings and samples. Despite substantial heterogeneity in individual intervention design, delivery and groups targeted, results indicate that a broad range of intervention types can successfully improve wellbeing. Methodological changes, such as greater use of control groups in intervention evaluation, can help future researchers and policy makers further understand what works for mental wellbeing.
Current Status and Correlation of Physical Activity and Tendency to Problematic Mobile Phone Use in College Students
Authors: Tong Wen-Xia , Li Bo , Han Shan-Shan , Han Ya-Hui , Meng Shu-Qiao , Guo Qiang , Ke You-Zhi , Zhang Jun-Yong , Cui Zhong-Lei , Ye Yu-Peng , Zhang Yao , Li Hua-Lan , Sun He , Xu Zhan-Zheng
Published: November 2022

Objective: To explore the effect of problematic mobile phone use on college students’ physical activity and their relationships. Methods: A cross-sectional study was conducted among 3980 college students from three universities in Jiangsu province by random cluster sampling. The International Physical Activity Questionnaire Short (IPAQ-SF) measured college students’ physical activity. The Mobile Phone Addiction Tendency Scale for College Students (MPATS) measured problematic mobile phone use tendencies. College students’ physical activity was measured by the International Physical Activity Questionnaire Short (IPAQ-SF), and the Mobile Phone Addiction Tendency Scale measured their mobile phone addiction tendency for College Students (MPATS). Results: (1) The proportions of the low-, medium-, and high-intensity physical activity were 83.5%, 10.7%, and 5.8%, respectively, with gender differences; The score of problematic mobile phone use tendency was 38.725 ± 15.139. (2) There were significant differences in problematic mobile phone use tendency among college students with different physical activity intensity (F = 11.839, p < 0.001, η2 = 0.007). (3) The level of physical activity was significantly correlated with the tendency of problematic mobile phone use (r = −0.173, p < 0.001). (4) Physical activity of college students could significantly predict the tendency of problematic mobile phone use (F (3,3605) = 11.296, p < 0.001). Conclusions: The physical activity of college students was mainly moderate to low intensity, while the tendency of problematic mobile phone use was high. College students’ physical activity level was one of the important constraints of problematic mobile phone use tendency.
Towards a Better Workplace Environment—Empirical Measurement to Manage Diversity in the Workplace
Authors: Gross-Gołacka Elwira , Kupczyk Teresa , Wiktorowicz Justyna
Published: November 2022

(1) Background: In this article, we explore the ever-present problem of achieving better results in the area of creating innovative and diverse human resources in the workplace environment through learning and inference from past actions. (2) Methods: An original proposal of five synthetic indicators was developed, corresponding to individual areas of the 5P architecture. In order to test the homogeneity of the index, exploratory factor analysis was used. The reliability of the new indicator was also assessed, both in total and in selected sub-areas. The value of the synthetic index was determined as a summary score in the selected areas (the sum of the values of individual diagnostic variables). Finally, the distribution of synthetic indicators WP1–WP5 was analyzed. (3) Results: By assumption, this analysis was performed to enable an empirical verification of the theoretical model, which combined the strategic, tactical and operational levels, delineating five steps (areas) that should be taken to create an organization open to diversity and its management. The presented approach also allowed for the visualization of the implementation of the organization’s activities in individual areas of diversity management expressed in the proprietary 5P architecture in many dimensions (planning, implementation and monitoring). In addition, the analyses confirmed that the individual dimensions of the diversity management architecture interacted with each other and that the direction of this correlation was positive: the development of diversity management in different areas occurred in parallel, but nevertheless, as can be seen from the values of the correlation coefficients, at a different pace/range. (4) Conclusions: The use of quantitative methods in the decision-making process of an organization can have a significant impact on the quality of its management. In the case of building an inclusive environment and implementing activities for diversity management, the proposed 5P architecture could significantly support this process. Therefore, it is recommended to use the proposed 5P architecture in practice, for example, to diagnose the scope and quality of actions taken for diversity management, as well as to build a diverse working environment in key areas of the organization.
Fatigue, Pro-Social Attitude and Quality of Life as Predictors of Empathy in Medical and Social-Oriented Students
Authors: Zdun-Ryżewska Agata , Sobczak Krzysztof , Rudnik Agata
Published: November 2022

Empathy is significant in professions that require establishing proper contact as a condition for providing help. Identifying factors related to empathy is important for understanding how to teach empathic behavior. The main goal of this study was to find variables related to empathy in a group of students from two universities: medical and social oriented (N = 1701). The study group consisted of female (81%) and male (19%) participants, aged between 18–20 (37%), 21–23 (49%), or 24 years and above (14%). A self-designed questionnaire was used to collect socio-demographical information, with additional questions (social self-esteem, prosocial attitude, subjective quality of life). Empathy was measured with the EQ-40, fatigue with CHFQ-PL, and stress with PSS-10. The results showed a statistically significant regression model for empathy. A high quality of life and having feelings of pleasure when helping other people allows to predict a high level of empathy, especially among females. Higher levels of fatigue and social self-esteem, the latter of which is measured here by the belief that you are more important than others, predicts lower empathy. There were no differences between students from two different kinds of universities when taking into consideration stress levels, subjective quality of life, and prosocial attitude. However, students from the medical university were more exhausted and more convinced that their value was greater than others, as compared to the students studying social sciences. When teaching empathic behavior, it is beneficial to attempt to maintain or restore students’ well-being and reduce fatigue and to teach how to achieve such effects in the future. Learning the balance between compassion, willingness to help, and self-compassion also seems to be important.
The Impact of Competitive Swimming on Menstrual Cycle Disorders and Subsequent Sports Injuries as Related to the Female Athlete Triad and on Premenstrual Syndrome Symptoms
Authors: Witkoś Joanna , Błażejewski Grzegorz , Hagner-Derengowska Magdalena , Makulec Kamila
Published: November 2022

Background: An athlete’s menstrual cycle may be seriously disturbed when she undertakes a physical activity that exceeds the body’s adaptive capacity and/or applies dietary restrictions. The main aim of this study was to assess the impact of swimming training undertaken by participants of sport clubs on disorders of the menstrual cycle. Methods: The study involved 64 female athletes. The questionnaire utilized in this study was composed by the authors, however some of the questions were based on Low Energy Availability in Females Questionnaire (LEAF-Q). Results: 31.26% of swimmers reported that the menstrual cycle was stopped for more than 3 months, of which 21.88% had a menstrual absence for more than 6 months and 9.38% between 3 months and 6 months. Years of training were a positive predictor of the ‘more profuse bleeding’. There was a negative correlation between the disorders of the menstrual cycle, the body weight of the female participants (p < 0.05) and the body mass index (p < 0.01). It was found that with the severity of the degree of disorder in the menstrual cycle, the number of injuries among the surveyed swimmers increased (p < 0.05). Conclusions: The correct body weight of the participants was a positive predictor of the absence of the menstrual cycle disorders among the majority of women practicing swimming. Disorders in the menstrual cycle occurring in a certain percentage of the swimmers positively correlated with the number of injuries recorded among these swimmers. Swimming has been shown to alleviate some of the premenstrual symptoms.
Ion-Modified Starch Film Enables Rapid Detection of Spoiled Fruit Juices
Authors: Qin Shijiao , Wu Yujia , Tian Hao , Liu Yun , Kan Huan , Hou Defa , Lin Xu , Zheng Yunwu , Zheng Zhifeng , Liu Can
Published: November 2022

Juice, as a liquid foodstuff, is subject to spoilage and damage due to complications during transport and storage. The appearance of intact outer packaging often makes spoilage and damage difficult to detect. Therefore, it of particular importance to develop a fast, real-time material to evaluate liquid foodstuffs. In this paper, starch films with pH response characteristics are successfully prepared by inorganic ion modification by utilizing whole starch and amylopectin as raw materials. The mechanical properties, stability properties, hydrophilic properties and pH electrical signal response indices of the films are analyzed and measured. The films exhibit good electrical conductivity values with 1.0 mL of ion addition (10 mmol/L), causing the composite film to respond sensitively to solutions with varying pH values. In the test of spoiled orange juice, the full-component corn starch (CS) film has more sensitive resistance and current responses, which is more conducive for applications in the quality monitoring of juice. The results indicate that modified starch films can potentially be applied in the real-time monitoring of the safety of liquid foodstuffs.
Characterization in Potent Modulation on Voltage-Gated Na+ Current Exerted by Deltamethrin, a Pyrethroid Insecticide
Authors: Lin Mao-Hsun , Lin Jen-Feng , Yu Meng-Cheng , Wu Sheng-Nan , Wu Chao-Liang , Cho Hsin-Yen
Published: November 2022

Deltamethrin (DLT) is a type-II pyrethroid ester insecticide used in agricultural and domestic applications as well as in public health. However, transmembrane ionic channels perturbed by this compound remain largely unclear, although the agent is thought to alter the gating characteristics of voltage-gated Na+ (NaV) channel current. In this study, we reappraised whether and how it and other related compounds can make any further modifications on voltage-gated Na+ current (INa) in pituitary tumor (GH3) cells. Cell exposure to DLT produced a differential and dose-dependent stimulation of peak (transient, INa(T)) or sustained (late, INa(L)) INa; consequently, the EC50 value required for DLT-stimulated INa(T) or INa(L) was determined to be 11.2 or 2.5 μM, respectively. However, neither the fast nor slow component in the inactivation time constant of INa(T) activated by short depolarizing pulse was changed with the DLT presence; conversely, tefluthrin (Tef), a type-I pyrethroid insecticide, can accentuate INa with a slowing in inactivation time course of the current. The INa(L) augmented by DLT was attenuated by further application of either dapagliflozin (Dapa) or amiloride, but not by chlorotoxin. During pulse train (PT) stimulation, with the Tef or DLT presence, the cumulative inhibition of INa(T) became slowed; moreover, following PT stimuli, a large tail current with a slowly recovering process was observed. Alternatively, during rapid depolarizing pulse, the amplitude of INa(L) and tail INa (INa(Tail)) for each depolarizing pulse became progressively increased by adding DLT, not by Tef. The recovery time constant following PT stimulation with continued presence of Tef or DLT was shortened by further addition of Dapa. The voltage-dependent hysteresis (Hys(V)) of persistent INa was differentially augmented by Tef or DLT. Taken together, the magnitude, gating, frequency dependence, as well as Hys(V) behavior of INa exerted by the presence of DLT or Tef might exert a synergistic impact on varying functional activities of excitable cells in culture or in vivo.
Proteomics in Inherited Metabolic Disorders
Authors: Chantada-Vázquez Maria del Pilar , Bravo Susana B. , Barbosa-Gouveia Sofía , Alvarez José V. , Couce María L.
Published: November 2022

Inherited metabolic disorders (IMD) are rare medical conditions caused by genetic defects that interfere with the body’s metabolism. The clinical phenotype is highly variable and can present at any age, although it more often manifests in childhood. The number of treatable IMDs has increased in recent years, making early diagnosis and a better understanding of the natural history of the disease more important than ever. In this review, we discuss the main challenges faced in applying proteomics to the study of IMDs, and the key advances achieved in this field using tandem mass spectrometry (MS/MS). This technology enables the analysis of large numbers of proteins in different body fluids (serum, plasma, urine, saliva, tears) with a single analysis of each sample, and can even be applied to dried samples. MS/MS has thus emerged as the tool of choice for proteome characterization and has provided new insights into many diseases and biological systems. In the last 10 years, sequential window acquisition of all theoretical fragmentation spectra mass spectrometry (SWATH-MS) has emerged as an accurate, high-resolution technique for the identification and quantification of proteins differentially expressed between healthy controls and IMD patients. Proteomics is a particularly promising approach to help obtain more information on rare genetic diseases, including identification of biomarkers to aid early diagnosis and better understanding of the underlying pathophysiology to guide the development of new therapies. Here, we summarize new and emerging proteomic technologies and discuss current uses and limitations of this approach to identify and quantify proteins. Moreover, we describe the use of proteomics to identify the mechanisms regulating complex IMD phenotypes; an area of research essential to better understand these rare disorders and many other human diseases.
Human Milk Oligosaccharide 2′-Fucosyllactose Inhibits Ligand Binding to C-Type Lectin DC-SIGN but Not to Langerin
Authors: Mukherjee Reshmi , Somovilla Victor J. , Chiodo Fabrizio , Bruijns Sven , Pieters Roland J. , Garssen Johan , van Kooyk Yvette , Kraneveld Aletta D. , van Bergenhenegouwen Jeroen
Published: November 2022

Human milk oligosaccharides (HMOs) and their most abundant component, 2′-Fucosyllactose (2′-FL), are known to be immunomodulatory. Previously, it was shown that HMOs and 2′-FL bind to the C-type lectin receptor DC-SIGN. Here we show, using a ligand-receptor competition assay, that a whole mixture of HMOs from pooled human milk (HMOS) and 2′-FL inhibit the binding of the carbohydrate-binding receptor DC-SIGN to its prototypical ligands, fucose and the oligosaccharide Lewis-B, (Leb) in a dose-dependent way. Interestingly, such inhibition by HMOS and 2′-FL was not detected for another C-type lectin, langerin, which is evolutionarily similar to DC-SIGN. The cell-ligand competition assay using DC-SIGN expressing cells confirmed that 2′-FL inhibits the binding of DC-SIGN to Leb. Molecular dynamic (MD) simulations show that 2′-FL exists in a preorganized bioactive conformation before binding to DC-SIGN and this conformation is retained after binding to DC-SIGN. Leb has more flexible conformations and utilizes two binding modes, which operate one at a time via its two fucoses to bind to DC-SIGN. Our hypothesis is that 2′-FL may have a reduced entropic penalty due to its preorganized state, compared to Leb, and it has a lower binding enthalpy, suggesting a better binding to DC-SIGN. Thus, due to the better binding to DC-SIGN, 2′-FL may replace Leb from its binding pocket in DC-SIGN. The MD simulations also showed that 2′-FL does not bind to langerin. Our studies confirm 2′-FL as a specific ligand for DC-SIGN and suggest that 2′-FL can replace other DC-SIGN ligands from its binding pocket during the ligand-receptor interactions in possible immunomodulatory processes.
Salicylic Acid Enhances Cadmium Tolerance and Reduces Its Shoot Accumulation in Fagopyrum tataricum Seedlings by Promoting Root Cadmium Retention and Mitigating Oxidative Stress
Authors: Luo Siwei , Wang Kaiyi , Li Zhiqiang , Li Hanhan , Shao Jirong , Zhu Xuemei
Published: November 2022

Soil cadmium (Cd) contamination seriously reduces the production and product quality of Tartary buckwheat (Fagopyrum tataricum), and strategies are urgently needed to mitigate these adverse influences. Herein, we investigated the effect of salicylic acid (SA) on Tartary buckwheat seedlings grown in Cd-contaminated soil in terms of Cd tolerance and accumulation. The results showed that 75–100 µmol L−1 SA treatment enhanced the Cd tolerance of Tartary buckwheat, as reflected by the significant increase in plant height and root and shoot biomass, as well as largely mitigated oxidative stress. Moreover, 100 µmol L−1 SA considerably reduced the stem and leaf Cd concentration by 60% and 47%, respectively, which is a consequence of increased root biomass and root Cd retention with promoted Cd partitioning into cell wall and immobile chemical forms. Transcriptome analysis also revealed the upregulation of the genes responsible for cell wall biosynthesis and antioxidative activities in roots, especially secondary cell wall synthesis. The present study determines that 100 µmol L−1 is the best SA concentration for reducing Cd accumulation and toxicity in Tartary buckwheat and indicates the important role of root in Cd stress in this species.