bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of umbilical cord blood miR-375 with neonatal respiratory distress syndrome and adverse neonatal outcomes in premature infants
Authors: Deng Yuling , Zhang Rong , Jiang Xiaona
Published: June 2022

Background: Neonatal respiratory distress syndrome (NRDS) is a common respiratory disorder occurring in premature infants, and some microRNAs (miRNAs) have been demonstrated to play critical roles in NRDS progression. This study aimed to measure relative expression of miR-375 in infants with NRDS, and further evaluate the clinical significance of miR-375 in predicting the onset and clinical prognosis of NRDS in infants. Methods: This study collected umbilical cord blood from 180 premature neonates, including 90 neonates with NRDS and 90 non-NRDS neonates. Quantitative real-time PCR was used to detect relative expression level of miR-375. The diagnostic value of miR-375 in screening NRDS neonates from control neonates and its predictive accuracy for clinical prognosis were evaluated by receiver operating characteristic analysis. The relationship of miR-475 with disease onset and clinical outcomes in NRDS infants was assessed by univariate and multivariate logistic regression analyses. Results: Relative miR-375 expression was upregulated in NRDS neonates, and high levels of miR-375 were observed in NRDS grade III-IV cases compared to those early-stage neonates. miR-375 had relatively high diagnostic accuracy to screen NRDS neonates and was independently associated with NRDS onset in infants. Moreover, relative miR-375 expression was upregulated in NRDS neonates with poor prognosis and could independently predict the clinical outcomes of NRDS neonates with considerable predictive accuracy. Conclusion: Umbilical cord serum miR-375 is elevated and associated with NRDS onset and clinical outcomes in NRDS neonates. Thus, miR-375 may serve as a biomarker for the diagnosis and prognosis of infants with NRDS.
Ganoderma lucidum polysaccharide inhibits the proliferation of leukemic cells through apoptosis
Authors: Zhong Mingxing , Huang Jiwei , Mao Pingxiang , He Chengming , Yuan Dongmei , Chen Changkun , Zhang Haiying , Hu Jing , Zhang Jingdong
Published: June 2022

Objective: To investigate the cytotoxic effect of polysaccharides derived from Ganoderma lucidum on T lymphocyte leukemia cells. Methods: Water-soluble polysaccharides were extracted from the fruit bodies of G. lucidum, purified, and characterized using HPGPC-MALLS and NMR. The cytotoxicity of G. lucidum polysaccharide fraction 5 (GLP5) to T lymphocyte leukemia cell line Jurkat and human immortalized epidermal cell line HaCat was assessed using MTT assay. Apoptosis was assessed using flow cytometry. Expressions of apoptosis-related genes in the cells after being exposed to GLP5 were detected using Western blot assay.Results: GLP5 was a β-(1→3) and β-(1→6) linked glucan. It inhibited the proliferation of Jurkat cells in a concentration-dependent manner and the half-maximal inhibitory concentration (IC50) was 34.5 mg/L but did not suppress the growth of HaCat cells. Apoptotic cells in Jurkat cells were detected to increase with increasing GLP5 concentrations. The expression levels of cleaved caspase-3 were significantly higher after the cells were exposed to 25 and 50 mg/L GLP5 when compared to non-exposed cells (Control). In addition, the expression levels of BAX and Bcl2 were significantly up- and down-regulated after treatment with GLP5 at 25 and 50 mg/L when compared with control (P<0.05), respectively.Conclusions: GLP5 has antiproliferative activity against Jurkat cells and the activity is likely mediated through the activation of apoptosis pathways.
A Review on Bioanalytical Method Development and Validation by Liquid Chromatography–Tandem Mass Spectrometry
Authors: Malviya Jitendra , Joshi Deshbandhu , Singh Bhadauria Raghvendra
Published: June 2022

The development of sound bioanalytical method(s) is of paramount importance during the process of drug discovery and development, culminating in a marketing approval. The objective of this paper is to review the sample preparation of drug in biological matrix and to provide practical approaches for determining selectivity, specificity, limit of detection, lower limit of quantitation, linearity, range, accuracy, precision, recovery, stability, ruggedness, and robustness of liquid chromatographic methods to support pharmacokinetic (PK), toxicokinetic, bioavailability, and bioequivalence studies. Bioanalysis, employed for the quantitative determination of drugs and their metabolites in biological fluids, plays a significant role in the evaluation and interpretation of bioequivalence, PK, and toxicokinetic studies. Selective and sensitive analytical methods for quantitative evaluation of drugs and their metabolites are critical for the successful conduct of pre-clinical and/or biopharmaceutics and clinical pharmacology studies.
comparison of the NSL-KDD dataset and its predecessor the KDD Cup ’99 dataset
Authors: Sahli Yassine
Published: June 2022

This study examines three datasets, notably the KDD Cup '99 and the NSL-KDD datasets, which are commonly used in intrusion detection research in computer networks. The KDD Cup '99 dataset contains five million records, each with 41 attributes that may be used to categorize malicious assaults into four categories: Probe, DoS, U2R, and R2L. Because it was developed by simulation over a virtual computer network, the KDD Cup '99 dataset cannot reflect real traffic statistics. Duplicate and redundant records from the KDD Cup '99 dataset are eliminated from the training and test sets, respectively, in the NSL-KDD dataset.
Inherent Mothering Ability of Indigenous Hen under Extensive Free-Range Management, A-Close Observational Study
Authors: Nyandebo Jesse Patrick Joseph , Bagla Victor Patrick , Kanu Saidu , Muana Abigail , Sesay Abdul Rahman , Umoh Magdalene Philips
Published: June 2022

Inherent mothering ability of the indigenous hen under extensive management is geared towards ensuring continuation of its lineage. Most of these attributes (feeding and predators response) are instinctive and transmitted to chicks during their first week of life to enhance their survival.

The study was carried out over a ten-years period base on direct keen observation of the indigenous hen from the point of attainment of puberty and associating with cocks up to the time it’s raising her own brood under extensive management and recordings of inherent and instinctive traits exhibited. Maternal behaviours like egg incubation; candling and sorting; egg turning; temperature regulation and hatching are in synchrony with the hatching machine. Chick brooding and rearing periods presents the most challenging time as she has to balance between two key responsibilities (feeding and chick protection), these it was observed she do diligently to ensure the propagation of its lineage though faced with huge challenges from predators and adverse weather conditions that reduce chick population reaching maturity.

This research findings recommends feed supplementation especially during incubation, brooding and chick rearing period and confinement and protection of young chicks from predators and adverse weather conditions until they reach weaning age.
Exploring the Student Teaching Interns’ Journey in an Online Mode of Teaching Delivery
Authors: Quinco-Cadosales Maria Nancy
Published: June 2022

The COVID – 19 pandemic resulted in significant educational reforms. Even the once-in-a-lifetime face-to-face student teaching experience has been transformed into a virtual reality. The havoc caused by today's difficulties prompted the creation of this article, which looked at the journey of student teaching interns as they completed online teaching demonstrations and other tasks as part of their student internship. Three sub-themes arose using Charmaz's (2006) constructivist grounded theory: introspection as self-revelation, embracing the roles and responsibilities as student teaching interns, and integration as self-revelation. These sub-themes point to the meta-theme of student teaching interns' molting phases as the theory. The theory describes the journey of student teaching interns as they face their fears via reflection, embrace the work at hand, and arrive at the stage of integration when they can be their best selves as teachers. Another investigation is necessary to assess the validity of the theory that arose from the research.
Banking Sector Stability in Sierra Leone: An Econometric Analysis
Authors: Johnson Leroy
Published: June 2022

This study assess banking sector stability in Sierra Leone using quarterly data over the period 2009-2019 of the fourteen banks in the sector. The study was carried out in the context of Johansen Cointegration estimation technique and it was found out that in the long run, total bank assets, gross loans positively influence banking sector stability whilst exchange rate had negative effect on banking sector stability. In the short run, total banking assets was also found to have a positive and statistically significant relationship. Arising from theaforementioned estimation results, this study recommends that banks transition to Basel three Capital Framework which is forward looking that shore up the stability of the banking sector and makes provisions for risks that will emanate in the banking realms of Sierra Leone. This is turn will facilitate smooth banking operations and fortifies public confidence in the banking sector.
Management Control Systems in Small and Medium-Sized Enterprises: A Case Study
Authors: Quinco-Cadosales Maria Nancy , Famacion-Quinco Daryl F.
Published: June 2022

Small and medium-sized enterprises (SMEs) are the pillar of the Philippine economy.  They comprise 99.6% of the total business establishments in the market.  Many studies have said that SMEs, particularly small enterprises, do not utilize management control systems (MCS) due to their simple organizational structure and limited resources.  Only a few studies have indicated that these firms have established and are using MCS even those sophisticated management accounting practices (MAPs) and information. This empirical study was conducted to get an understanding of the use and the form of MCSs applied in SMEs in Misamis Occidental and to explore on their implementation of control.  The study used the case study method. The study included 46 SMEs surveyed and seven SMEs interviewed.  The companies have already been in the industry for more than 10 years and employed from 10 to 199 persons.  They are a combination of traditional and modern enterprises due to the generation of the owners/managers handling the business operations.  The results suggest that SMEs in Misamis Occidental do use a wide range of MCS practices and information although many practices are not integrated as highly and systematically into their normal operations based on the data of adoption rates and ranks.  The results also indicate that MCS are themed along the lines of financial controls, clan controls, customer-oriented controls, relationship controls, and strategic-oriented controls.  This shows a combination of traditional MCS and new sophisticated MCS which adds to the knowledge that SMEs do practice and adopt MCS in their operations.
Customer Loyalty Through Retailer Brand Equity: Perspectives from Male Alcoholic Beverage Consumers
Authors: Esinu Agordoh Ms. Lovelace
Published: June 2022

The service business has risen to prominence in recent years as the primary driver of economic growth. As such competing organizations have consistently supplied higher service quality and a positive brand image to gain consumer pleasure and loyalty in the current competitive environment. The primary purpose of this study is to explore the motivational factors that enrich customer loyalty through retailer brand equity. The qualitative research method was used in the collection of data. Ten male consumers of alcoholic beverages were interviewed to solicit answers about their experiences with retail outlets during their purchases. In-depth, open-ended questions were asked during data collection. The findings reveal themes such as customer experience, brand trust, and customer satisfaction as customer motivations that enhance repurchase behaviours at the selected retail outlets. In addition, these motivational factors also show that retailer brand equity promotes customer satisfaction, which leads to customer loyalty.
Reflecting on the Impact of COVID-19 on Tourism in Italy
Authors: Singh Akanksha , Sahu Pooja
Published: June 2022

Italy was the first major western country to face the viral disease, which originated in China late last year and has spread around the world. Italian authorities have recorded some 2,29,858 confirmed cases and 32,785 death. Tourism is known as one of the most growing sector in Italy which is encouraging economic growth and development by giving employability of large sector of the working population. This paper is focusing on Coronavirus Disease (COVID-19) and its impact on Tourism Industry of Italy after a complete lockdown. In this paper we will come to know about popular tourist places in Italy and how they are affected after lockdown which has affected the economy of the country to a large extent. This paper also focused on why Italy was adversely affected due to Coronavirus and reasons behind it. Government has also taken various decisions for removal of COVID-19 and its impact on tourism industry of Italy.
Security Challenges for Digital Transformation in Saudi Arabia
Authors: Assiri Khalid , Almdani Khalid , Al Saeedi Hassan , Softah Abdullah , Khogeer Sultan
Published: June 2022

Saudi organizations are increasingly using digital technologies. Despite widespread efforts to benefit from digitalization, few companies can claim to have seen significant results. Organizational employees have been linked to the success or failure of the digitization process in a growing body of studies.  Three hypotheses regarding the security of the digital transition have been suggested in this study. These hypotheses include determining how security has evolved because of the increased use of digital systems, as well as determining the best risk management strategies. A range of public and private Saudi entities will get an electronic survey as part of this study.  In summary, we have found that as the digital transformation grows, the security risk increases as well, necessitating the implementation of a robust security system and the most effective risk management measures. Additionally, the business must include employees in the development and implementation of the digital transformation to maintain their loyalty. Additionally, all employees must understand and agree on the digital transformation goals, objectives, and plans. Successful business leaders can build a compelling vision, unite, and engage staff to adopt new methods of doing business.
“The Acronyms Club” Has the Ukraine Conflict Exposed the West and its History? The Most Comprehensive Study into How U.S. Hegemony Denies Sovereignties of Nations.
Authors: Miller Antony D. , Illipinar Gürsel
Published: June 2022

Von Clausewits once wrote [in many of his aphorisms]: “War is the continuation of policy with other means.” (Howard; Paret 1974,). Firstly, this comprehensive body of research is an empirical attempt to purposely examine for the first time, how the West has continued to influence many countries without honouring their sovereignty. Secondly, this paper aims to validate, that the Russian Federation, made the correct decision by escalating the 8-year conflict in Ukraine, as a protectionary measure, thus, confirming the globe’s new “multipolarity” simultaneously; since the inception of military activities. Furthermore, this study will illustrate the decline of a unipolar world additionally via the US Dollar weaponization policies, resulting in denying sovereign states their dignity, from continuing confirmed illegal punitive sanctions. Thirdly, has both the three-year [SARS-CoV-2] pandemic, and the following Ukraine conflict, exposed the West’s true nature of an immoral gambit’s true nature more publicly? Referring to “The Acronyms Club”: US, UN, EU, NATO, IMF, WB and the OSCE, -has it been exposed within its hegemonic conduct, since the cessation of the Cold War? Fourth, it will be confirmed via documented history and acts recently that the UN Charter System i.e., Articles 3, 6, have been ignored on many fronts, consequently, the organization has become redundant and untruthful in today’s epoch. Fifth, this objectional hypothesis will notate the historic factors which has led to distrust of western society, by eastern states; mainly due to its Western leadership of false promises with misinformation. Thus, has Russia’s action exposed an inflection point within the West and neo-liberal economic policy? Finally, the hypothesis being, why had the Russian Federation, purposely venture into Ukrainian territory, via “Special Military Operations” and was there provocation prior to doing so? Finally, has the Acronyms Club inadvertently created a “Cold War” 2.0 within Eastern reviewed trading practice?
Single or Divided Administration of Cisplatin Can Induce Inflammation and Oxidative Stress in Male Sprague-Dawley Rats
Authors: Sidharta Brigitte Rina Aninda , Purwanto Bambang , Wasita Brian , Widyaningsih Vitri , Soetrisno Soetrisno
Published: June 2022

BACKGROUND: Cisplatin is one of the most potent chemotherapy drugs to treat various types of cancer, however the use of cisplatin has some the adverse effect, such as the increase of oxidative stress and inflammation by malondialdehyde (MDA) and nuclear factor kappa B (NF-kB) activation. Since the dosing of cisplatin is critical, we observed the effect of single and multiple doses of cisplatin injection on rats’ inflammation and oxidative stress level.METHODS: Total of 27 male Sprague-Dawley rats were divided into 9 sub-groups, each consisted of 3 rats. The baseline sub-group received no treatments; Group 1 (sub-group 1.1, 1.2, 1.3, and 1.4) were administered one single dose of 5 mg/kg BW/intravenously (i.v) of cisplatin; and Group 2 (sub-group 2.1, 2.2, 2.3, and 2.4) were given 0.2 mg/kg BW/i.v of cisplatin twice a week for two months. Rats were observed for their body weight, NF-kB, and MDA level based on the assigned group. RESULTS: Body weight loss was observed in the 1st week after treatment for Group 1, and 7th week for Group 2. Group 1 and Group 2 showed increasing level of NF-kB and MDA since the 1st observation, which was the 1st week and 5th week, respectively. NF-kB and MDA and levels were also significantly increasing in both groups for every week of observation (p<0.05).CONCLUSION: Cisplatin injection either in single or divided dose can induce inflammation and oxidative stress thus decrease the body weight. However, dividing cisplatin in smaller dose can delay the inflammation effect on subjects.KEYWORDS: cisplatin dose, MDA, NF-kB, body weight, inflammation, oxidative stress
Parkia speciosa Seeds Ethanol Extract as Co-chemotherapeutic Agent for Doxorubicin Toward Tongue Cancer
Authors: Mahanani Erlina Sih , Arifin Ikhsan Nur , Ihsan Arya Nur , Lukitasari Yusrina , Sandra Ferry
Published: June 2022

BACKGROUND: Parkia speciosa seeds have been reported to have an anticancer property due to the presence of various antioxidant compounds. Since the potential uses of P. speciosa for the tongue cancer has not been clearly disclosed, we conducted a study to investigate anticancer properties of P. speciosa seed ethanol extract (PSSEE) as well as its effect on cardiac cells.METHODS: Tongue cancer rat model were treated with/without Doxorubicin and various concentrations of PSSEE. After treatment, tongue and heart samples were collected and processed further for histological examinations. Tongue epithelium thickness and damaged heart tissues was observed by HE staining, while tongue cancer cell proliferation was assessed by Ki-67 immunohistochemistry. Analyses were performed under an upright light microscope to measure tongue epithelium thickness, state of cancer cell proliferation, and degree of heart tissue damage.RESULTS: Addition of 400 mg/kg body weight (BW) PSSEE to 4.6 mg/kg BW Doxorubicin reduced the average tongue epithelial thickness and Ki-67+ cells number. Upon addition of PSSEE to Doxorubicin, the damage of heart tissue was reduced in a concentration dependent manner. Among all groups, the group of tongue cancer treated with 4.6 mg/kg BW Doxorubicin and 400 mg/kg BW PSSEE had the lowest percentage as well as the lowest degree of heart tissue damage.CONCLUSION: Since addition of PSSEE to Doxorubicin reduced epithelial thickness, number of Ki-67+ cells and heart tissue damage, PSSEE could be a potential co-chemotherapeutic agent for Doxorubicin toward tongue cancer.KEYWORDS: Parkia speciosa, Doxorubicin, tongue cancer, epithelial thickness, Ki-67, cardiotoxicity, co-chemotherapy
Immunomodulatory Activity of Agarwood Aquilaria malaccensis Lamk. Leaf Extracts on Staphylococcus aureus-infected Macrophages in vitro
Authors: Yana Hiqmah Yusi , Hidayati Lisna , Wijayanti Nastiti , Nuringtyas Tri Rini
Published: June 2022

BACKGROUND: Aquilaria malaccensis has been consumed as herbal medicine, and in vitro study showed that the leaf extract possesses high antioxidant activities. A brief preliminary study indicated that A. malaccensis showed a promising immunomodulatory activity when evaluated using latex beads. This current study aimed to evaluate the immunomodulatory activity of A. malaccensis leaf extract on the macrophage, which was challenged with pathogenic bacteria Staphylococcus aureus.METHODS: Bioactivity was determined by evaluating the phagocytic capacity of macrophages isolated from Mus musculus against S. aureus. First, the cytotoxicity of extracts on macrophages was evaluated using MTT assays, and the IC50 value was used to determine the dose of immunomodulatory assays. The highest toxicity was observed on chloroform extract with an IC50 value of 111.4 µg/mL. Therefore, the treatment was 100 and 50 µg/mL. Two parameters, including the phagocytic activity and phagocytic capacity of macrophages infected with S. aureus, were used to evaluate immunomodulatory activity. The analysis of variance was done at p<0.05 to determine the significant difference among treatments.RESULTS: Chloroform and ethanol extracts at a 50 µg/mL concentration showed the best results with the phagocytic activity of 82.33%±9.61% and 80.33±1.53%. The ethyl acetate showed lower phagocytic activities of 70.67±1.53. All extracts significantly increased phagocytic activity and phagocytic capacity, and the results differed significantly between negative and positive controls. Thin-layer chromatography indicated that the extract contained terpenoid, flavonoid, phenolic, and tannin.CONCLUSION: A. malaccensis leaf extracts showed immunomodulatory activity. Both chloroform and ethanol extracts showed comparable activity, while the ethyl acetate extract was lower. The extracts contained diverse bioactive compounds that may support activating macrophage cells for immunomodulatory activity.KEYWORDS: Aquilaria malaccensis, immunomodulator, phagocytosis, macrophages, Staphylococcus aureus
TNF-α, VEGF, and Procalcitonin Levels Dynamic Changes During Severe Traumatic Brain Injury
Authors: Hasan Diya , Alzuabe Mu’ad , Ismail Yazan , Al Tibi Ahmad , Abdelnour Amid
Published: June 2022

BACKGROUND: The variety of traumatic brain injury (TBI) creates difficulty in evaluating its level and the clinical outcome correctly. This study aimed to analyze the level variations and dynamic of serum biomarkers, such as tumor necrosis factor (TNF)-α, vascular endothelial growth factor (VEGF), and procalcitonin (PCT) in response to severe TBI.METHODS: Intravenous blood samples were collected from 20 TBI subjects at different time points: 0, 12, 24, and 48 hours. The serum levels of TNF-α, VEGF, and PCT were measured using specific monoclonal antibodies by quantitative sandwich enzyme-linked immunosorbent assay (ELISA).RESULTS: In 0, 12, 24, and 48 hours, the serum levels were significantly higher for TNF-α (p<0.0001), VEGF (p<0.0001) and PCT (p<0.0001) compared to the healthy control. In comparison to admission time point, TNF-α had elevated significantly (p<0.001) at 24 hours. PCT showed a significant increase after 48 hours (p<0.02) and VEGF showed no significant differences. Comparing the 3 biomarkers dynamic changes at 0, 12 and 24 hours, PCT level showed to be lower than VEGF and TNF-α levels, while VEGF level showed to be higher than PCT and TNF-α levels. However after 48 hours, PCT level (0.25 ng/mL) had elevated more than VEGF (0.21 ng/mL) and TNF- α (0.18 ng/mL) levels.CONCLUSION: Monitoring PCT in comparison to VEGF and TNF-α can be used to assist the progress of severe TBI, since PCT level progressive changes were associated with time increase.KEYWORDS: trauma, TNF-α, VEGF, PCT, Glasgow Coma Scale
Effect of Dietary Supplementation of Ferrous Sulphate on Growth, Immunocompetence Traits, Carcass Quality and Meat Composition of Turkey Poults
Authors: Sharma Ankit , Bhattacharyya Amitav , Shukla Pankaj Kumar , Kumar Vinod , Singh Vaibhav Kumar
Published: June 2022

Background: Inorganic iron compounds have a positive effect on the health and growth of the broiler chickens. However, limited work has been done in Turkeys. Thus a study was conducted to assess the effect of dietary supplementation of ferrous sulphate on the growth, immunocompetence traits, carcass quality and meat composition of Turkey poults. Methods: Day old turkey poults (n=96) were distributed into four treatment groups (T1, T2, T3 and T4) having 3 replicates of 8 birds each. The poults in T1 were fed (control) basal diet, while for birds in T2, T3 and T4, FeSO4 was supplemented @ 80, 120 and 160 mg/kg of feed, respectively. Result: Weekly body weight gain was significantly higher in T4 than T1 and T2 birds at 6th (P less than 0.01) and 7th week (P less than 0.05). Phase wise body weight gain was also significantly higher (P less than 0.05) in T4 than T1 and T2 during 4 to 8 weeks and 0 to 8 weeks (P less than 0.01). Weekly feed conversion ratio of T4 group was significantly better (P less than 0.01) at 6th week and 7th week than T1 and T2 group birds. The birds fed with T4 had significantly (P less than 0.05) higher foot web index compared to T1 and T2 group birds. Iron supplemented groups had significantly (P less than 0.01) higher dressing per cent. T4 had significantly (P less than 0.05) higher deposition of iron in thigh muscle. Thus, dietary supplementation of FeSO4 @ 160 mg/kg resulted in better growth performance, immunity, significantly higher dressing per cent and significantly higher deposition of iron in thigh meat cuts.
Nutritional Components and Quality Evaluation of Coilia nasus Muscle from Offshore of the Yangtze Estuary
Authors: Song C. , Li Y.G. , Zhao F. , Liu R.H. , Feng G.P. , Zhang T.T. , Zhuang P.
Published: June 2022

Background: Coilia nasus was one of the important economic fish in the Yangtze Estuary. The meat of C. nasus is tender and delicious, which is deeply loved by people. With the ban on fishing in the Yangtze River, a large number of “C. nasus from the sea” have appeared in the market. At present, the nutritional status and its true source are not clear. Therefore, the nutritional composition and quality of offshore C. nasus were analyzed to identify its source and evaluate its development and utilization potential according to its nutritional quality in the future. Methods: The muscle nutritional components and quality of offshore C. nasus were analyzed according to the methods of national standards of China. Result: The content of essential amino acids (EAA) in dry sample was 57.06%±7.39%. The first limited amino acid was tryptophan (Trp), the essential amino acids index (EAAI) was 83.05 and the F-value was 2.37. The total content of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in fatty acids were 10.67%±0.46%, the ratio of DHA/EPA was 1.74%±0.05%. This investigation indicates that the muscle of C. nasus from offshore of the Yangtze Estuary contained rich amino acid such as glutamate (Glu) and lysine (Lys) and sufficient polyunsaturated fatty acids such as DHA and EPA.
​Studies on Interrelationship and Path Coefficient Analysis in Okra [Abelmoschus esculentus (L.) Moench]
Authors: Rai Mritunjay , Singh R.K. , Sharma Vijay , Mishra A.C. , Dwivedi S.V.
Published: June 2022

Background: Okra [Abelmoschus esculentus (L) Moench] is an important vegetable crop widely grown in tropical and subtropical parts of the world. Okra is high yielding crop under a good cropping system. However, its yield potential has been grossly affected by poor cropping system, use of crude implement, poor soil and insect pest infestation. For improving okra through conventional breeding and selection, it is essential to have adequate knowledge of association that exists between yield and yield related characters for the identification of selection procedure. The knowledge of such mutual relationship between fruit yield and its contributing components can significantly improve the efficiency of a breeding programme through the use of appropriate selection indices. Methods: A study of correlation and path analysis was undertaken in 18 genotypes of okra for fruit yield and its component traits at Vegetable Research Centre, Banda University of Agriculture and Technology, Banda, (U.P) during summer and rainy season-2019. Result: It was observed that during summer season fruit yield per plant was positively and significantly correlated with leaf area, number of primary branches per plant and number of fruits per plant and in rainy season plant height, number of nodes and number of fruits per plant showed positive and significant association with fruit yield per plant at genotypic and phenotypic level. During both the season it was observed that estimates of genotypic correlation coefficients were in most cases higher than their corresponding phenotypic correlation coefficients. In the present study during summer season leaf area (0.760) had maximum direct contribution towards fruit yield per plant followed by number of fruits per plant (0.447). However, days to opening first flower exhibited highest negative direct effect (-1.109). During rainy season leaf area (3.274) had maximum direct contribution towards fruit yield followed by days to opening first flower (2.828). However, days to first harvesting (-4.630) exhibited highest negative direct effect. The study suggested that the improvement in yield per plant will be efficient if the selection is based on leaf area, number of fruits per plant, plant height, number of branches per plant and number of nodes per plant.
Examination of Physical Activity and Emotional Status of University Students
Authors: ŞAHİN Muhammed
Published: June 2022

Amaç: Bu araştırmanın temel amacı, COVID-19 kapsamında alınan önlemlerin üniversite öğrencilerinin fiziksel aktivite davranışlarını nasıl etkilendiğini belirlemek ve fiziksel aktivitenin öğrencilerin duygu durumları üzerindeki etkisi hakkında bilgi edinmektir.

Materyal ve Metot: Araştırmanın örneklemini basit şeçkisiz örnekleme ile veri toplanan 408 öğrenci oluşturmaktadır. Araştırmanın verileri çevrimiçi anket yolu ile toplanmıştır. Araştırmanın verileri, kişisel bilgi formu, uluslararası fiziksel aktivite anketi kısa formu ve pozitif ve negatif duygu ölçeği yoluyla toplanmıştır. Verilerin normalliği göz önünde bulunarak istatistiksel analizlerde tanımlayıcı istatistiklerin yanı sıra hipotez testleri için, T-Testi/Mann Whitney U, Ki-Kare Analizi ve Manova Analizi kullanıldı. Son olarak bağımlı ve bağımsız değişkenler arasındaki etki düzeyinin belirlenmesi amacı ile Cohen’s d değerleri incelendi.

Bulgular: Araştırma bulgularına göre, haftalık metabolik eşdeğeri (MET) toplam puanı baz alındığında, öğrencilerin %31,1’inin inaktif, %49’1’inin minimal aktif ve %19,8’inin yeterince aktif düzeyde olduğu görüldü. Fiziksel aktivite düzeyine bağlı olarak öğrencilerin duygu durumları üzerinde anlamlı farklılaşmanın meydana geldiği görüldü. Kadın öğrencilerin pozitif duygu puan ortalamalarının erkek öğrencilere kıyasla anlamlı bir şekilde daha yüksek olduğu görüldü. Bu duruma karşın negatif duygular ve toplam fiziksel aktivite düzeyinde kadın ve erkeklerin benzer ortalamalara sahip olduğu görüldü.

Sonuç: Sonuç olarak; üniversite öğrencilerinin fiziksel aktivite düzeylerinin duygu durumları üzerinde farklılık oluşturduğu görülmüştür. Cinsiyetin pozitif duygular üzerinde etkili olduğu buna karşın negatif duygular ve toplam fiziksel aktivite düzeyleri üzerinde ise etkili olmadığı söylenebilir.
ENVIRONMENTAL IMPACTS OF HUMANITY’S CARELESSNESS PART II: INDUSTRIAL WASTES AND AQUATIC HAZARDS
Authors:   Peoples’ Friendship University of Russia, Rajesh Ranjit , Galchenko A.V. ,   Federal Research Centre of Nutrition,  Biotechnology and Food Safety
Published: June 2022

It is a well-known fact that human beings are in the process of rapidly modernizing the world by utilizing various natural resources at an unprecedented speed. The accomplishment can initially be mistaken as human’s great achievement, but during the course of this swift development, we have been adding extra pressure on the envi-ronment, especially by disposing the harmful chemicals of industry. Secondly, we humans are also overly using the limited sources of nature, which is resulting in its depletion, eventually interrupting the natural cycle. Metals are the indispensable raw material for constructing infrastructures and for producing electronic products. However, extracting these metals from their corresponding ores can inflict serious consequences if no precautions are taken. Similarly, the everchanging fashion industry has exponentially raised the demand for cotton, which has eventually encouraged people to exploit the natural resources like water even more, resulting in climate change and even drying up of the whole sea in some cases. These activities also impose a formidable threat to the environment we live in and even can lead to the end of human existence. Due to human’s carelessness, the concentration of harmful chemicals in water, soil, and the air is already far higher than the permissible upper limit in many regions. These unacceptable higher levels of these harmful chemicals directly affect the health of not only human beings but all the living organisms living on the Earth. If the process is not curbed on time, we humans, with other wildlife and innocent organisms are bound to pay a hefty price.
La representación de Dioniso en los fragmentos de la Licurgía de Esquilo
Authors:   Universidad Nacional de Hurlingham, Instituto de Educación, Argentina, Perczyk Cecilia J.
Published: June 2022

My purpose in this paper is to analize the trilogy Lycurgeia of Aeschylus in order to provide an insight into the characterization of Dionysus in the tragic genre. The extant fragments describe his androgynous appearance and the effects of his arrival in Thracia. Other sources on the same myth will be included; particularly I will focus on Euripides’ Bacchae, because of its links with the myth of Pentheus.
La traducción de De rerum natura, de T. Lucrecio Caro: aspectos teóricos y prácticos
Authors:   Universidad de Buenos Aires / Consejo Nacional de Investigaciones Científicas y Técnicas, Argentina, Pégolo Liliana , Abecian Camilo Néstor ,   Universidad Tecnológica Nacional, Argentina, Durán Laura Carolina ,   Universidad de Buenos Aires, Argentina, Pizzi Matías ,   Universidad de Buenos Aires / Consejo Nacional de Investigaciones Científicas y Técnicas, Argentina, Russo Nicolás ,   Universidad de Buenos Aires / Consejo Nacional de Investigaciones Científicas y Técnicas, Argentina
Published: June 2022

This article brings up to discussion the idea of translation as a cognitive work which creates transitivity relations among linguistic codes. This phenomenon will be analyzed from a double perspective: the act of translating and the transmission by Lucretius of Epicureanism in Latin. So several aspects of theory of translation will be presented which have been used by the authors of this paper in their new Spanish translation of De rerum natura (2020). Moreover, it will be demonstrated how Lucretius developed meaningful semiotic chains in the Epicurean tradition and a linguistic theory in which words build a structure according to Nature’s order.
La fuerza en la Ilíada. Las lecturas de Homero de Simone Weil y Rachel Bespaloff
Authors:   Universidad de Murcia, Spain, Morales Ortiz Alicia
Published: June 2022

In the turbulent Europe of the World Wars, two French thinkers of Jewish Origin wrote both essays on the Iliad: Simone Weil (The Iliad, or the Poem of Force, 1940-1941) and Rachel Bespaloff (On the Iliad, 1943). Both writers have in common the return to the foundational texts of Western culture —Homer in the Classical tradition and the Bible and the Gospels in the Christian tradition— to rethink war and barbarism. This paper analyses the concept of ‘force’ in both authors, their similarities and differences, in order to conclude on the way in which this notion determines their interpretation of the Homeric poem.
Competition: Provision or Barrier for the Growth of Scientific Knowledge?
Authors: Tambovtsev Vitaly
Published: June 2022

The aim of the article is to analyze the competition concept’s content in science and the relationship between differences in this content and estimates of the competition impact on the growth of scientific knowledge. It is shown that at present there are two types of competition in science: “natural”, inseparable from the scientific knowledge production process, and “artificial”, generated by the widespread introduction of neoliberal science policy in different countries. The first type of competition exists between the creators of new scientific knowledge, the second one – between individuals called upon to perform the supportingfunctions necessary for the scientific knowledge production. Competing for their positions in bureaucratic hierarchies, these individuals use measures that give rise to various forms of researchers’ misconduct that damage the scientific knowledge production processes. It is concluded that the distinction between two types of competition in science will allow a more detailed and correct analysis of the processes taking place in science as a whole and in research organizations.
Digital Transformation of Research Communications: Academic Journal as an Electronic
Authors: Semenov Evgeny , Sokolov Dmitry , Gaydin Boris
Published: June 2022

The article discusses characteristics and main stages of production of an electronic academic journal as one of the most important elements of contemporary research communication. The authors examine the advantages of electronic periodicals from the point of view of the development of scientific communications, as well as the role of an electronic scholarly journal in the life of academic community which is forming around digital platforms (primarily around research social networks). The conclusion is that most of the issues with the electronic format of a peer-reviewed publication have been resolved over the past decades,and remaining difficulties are most often associated with the degree of qualification of authors and editors which is needed to prepare well-structured metadata and full-text articles.
On Russian Scientific-Technological Complex in Autonomous Conditions
Authors: Skazochkin Aleksander
Published: June 2022

The article presents a brief analysis of the socio-political situation that has developedin Russia as a result of sanctions and isolation, with an emphasis on the problems of thefunctioning of the scientific and technological complex. The problems of informational isolationof scientific organizations in Russia and the evaluation of scientific institutions of “unfriendly”countries, the possibility of correcting the volume of funding for the initiatives of theGovernment of the Russian Federation related to import substitution and the developmentof scientific infrastructure, the problems of intellectual property of “unfriendly” countries areindicated, as well as the possibilities of changing the governance of the scientific and technologicalcomplex, to obtain real results for the economy in autonomous conditions.
Russian Socio-Humanistic Science in Conditions of Forced Isolation
Authors: Yurevich Andrey
Published: June 2022

According to the author, Russian science was in a state close to forced isolation before, as a result of which it resembled a car with one-sided transparent windows: we had a good idea of what was happening in Western science, it had vague ideas about what was happening in our country. The author also believes that the weakening of ties with Western science will inevitably result in strengthening ties with eastern science, primarily with Chinese and Indian, and in the structure of the problems studied by socio-humanitarian disciplines, will be such problems as population migration, conflicts of the migrating and receiving population, etc., which are particularly aggravated during wars, will come to prominence. This science, most likely, will pay more attention to countries that exist in conditions of forced isolation – Iran, North Korea, Cuba, etc. The author considers the short-sighted policy of the West, which consists in excluding Russia from international associations of scientists.
Will capitalism die? Reflections on the Capitalism of the Past, Present and Future
Authors: Grinin Leonid , Malkov Sergey , Grinin Anton , Korotayev Andrey
Published: June 2022

In the article, the authors pose and consider in detail the extremely topical question of whether capitalism has a future or will it be replaced by some new system. And if there is a future, then what kind of future is it? These are not new questions, but in the last few years they have acquired exceptional importance, since not only the left, but also representatives of the largest financial capital have started talking about the end of capitalism. The article deals with the following questions: what is capitalism as a way of life and as a system; what was the evolution of capitalism; what are his potentialities. In addition, various scenarios are considered and forecasts are given for the next 50–100 years. It is assumed that in the next few decades the development of capitalism may proceed differently in developed and developing countries, resulting in a complex continuum of types, transitions, combinations and forms of capitalism. The authors believe that capitalism will be inevitably transformed to one degree or another, but the degree of such transformation can vary greatly. Various scenarios for the future of capitalism are considered: from maintaining its leading role to reducing capitalism to one of a few socio-economic subsystems.
Dynamics of subjective power status
Authors: Kozyreva Polina , Smirnov Aleksandr
Published: June 2022

The article presents the results of the analysis of the features of self-identification of Russian citizens in the power space of the post-Soviet society. The empirical base of the study is formed by the data of the Russian Longitudinal Monitoring Survey (RLMS-HSE) by HSE University (1994–2020). The study revealed a positive, but very moderate and not always consistent dynamics of Russian citizens' assessments of their position in the power space. However, despite the fact that Russians have become more optimistic about their ability to influence current events, many of them still feel that they are not active subjects, but rather passive and helpless objects in the system of power relations. There has been established a significant negative, but not strong, correlation between self-assessment of power status and age, as well as a more significant positive correlation between subjective power status and the level of education and professional status closely related to it.

Self-assessment of power status is enhanced by individuals´ belonging to professional groups, whose representatives are more associated with prestigious, highly skilled and highly paid work. A positive correlation has been established between a person's self-determination in the power space and the level of his involvement in professional activities, especially in those with leadership and management functions. A positive correlation is clearly recorded between self-assessment of power status and assessment of the level of respect by others, but the strongest is the relationship between assessments of one's position on the power scales and material well-being. Possession of power expands the resource base of an individual and increases his chances of success in realising life goals. A positive perception of one's professional qualities and achievements, participation in various forms of social and political life significantly increases self-assessment of power status. The most significant factors acting in the opposite direction include the cessation of full communication with other people.
Classification of network social movements in the cities of Southwestern Siberia regions
Authors: Shashkova Yaroslava , Kachusov Dmitry
Published: June 2022

The article presents the results of the study of urban Internet communities of a causal nature in the regions of Southwestern Siberia. Communities are analysed by variables: the degree of their development, the number of participants, the goals and objectives set, the forms of activity used. These communities were identified in social networks and messengers such as VKontakte, Facebook, Twitter, Odnoklassniki, Instagram, Telegram, as well as among YouTube channels and specialized sites. The informatisation of modern society provides citizens with more and more opportunities to participate in public life and establish horizontal communications. This is combined with the processes of raising the level of civic consciousness and the search for "workarounds" for participation in public politics. Both of these tendencies lead to more and more active involvement of citizens in the processes of self-organisation and participation in various associations. This leads to an increase in the number of urban problematic (causal) communities and in the number of their participants, the creation of new projects, and the massisation of their actions. There can be distinguished two main vectors for the development of such urban communities: urban protection and environmental. The first direction deals with the issues of arranging the living environment of citizens and creating "places of application" of causal civil activity, with problems of combining commercial, social, historical and cultural principles in the development of cities. The second one deals with the issues of protecting the natural environment, improving the living conditions of citizens, changing the consciousness and behaviour of people towards those more environmentally friendly. The set of methods used by all these communities is very wide: information campaigns in media and the Internet, filing petitions and appeals, organising of practical activities in the direction of their work, educating citizens, holding pickets and other public events, establishing contacts between civil society and government. It should be noted that there is no strict distinction between the communities of the two main problem areas, since the tasks they strive to solve (for example, the preservation of green areas in cities, the fight against landfills, etc.), as well as the composition of the participants, partially coincide.