bluuebunny/crossref_metadata_2025 huggingface dataset:
Financial incentives for model change in primary health care in São Paulo municipalities
Authors: Duarte Ligia Schiavon , Viana Mônica Martins de Oliveira , Scalco Nayara , Garcia Mariana Tarricone , Felipe Luiz Victor
Published: April 2023

Abstract This article aims to characterize financial transfers within the scope of the Primary Care Block to the municipalities of the state of São Paulo, in the period between 2011 and 2017, and its relationship with the health care model change in Primary Health Care (PHC). This is a descriptive and exploratory study, of quantitative nature and with a retrospective longitudinal section. Transfers that occurred within the scope of the Variable Primary Care Floor (Variable PCF) were analyzed, aggregated according to its link with the model change. Family Health Strategy (FHS) coverage, number of home visits, and the percentage of municipalities that adhered to the Program for Access and Quality Improvement in Primary Care (PMAQ) were also considered. The results indicate the relevance of the Incentives for model change in the financing of primary health care in the state of São Paulo, especially for small municipalities, suggesting the interest of these municipalities in implementing the proposed measures. However, there are obstacles to identifying changes in practices, thus the current health care model is not properly explained from the analyzed indicators. In conclusion, complementing the use of funding as a model change-inducing device with evaluative processes specifically aimed at consolidating comprehensive PHC is needed.
Segura sua mão na minha: uma conexão entre neurociência e Educação
Authors: Koide Adriana Batista de Souza , Tortella Jussara Cristina Barboza
Published: April 2023

Resumo Fomentada pela desigualdade e pela pobreza, a vulnerabilidade social pode impactar negativamente na vida humana. Avanços da neurociência indicam que tais consequências ganham novos contornos quando há estímulos para o cérebro em construção. Nesse sentido, o objetivo central do corrente estudo consiste em compreender as possibilidades para melhorar o desempenho da aprendizagem, em um contexto escolar de alta vulnerabilidade social, por meio de práticas pedagógicas que desafiem as funções executivas. Trata-se de um estudo de caso, descritivo exploratório, cujo método dedicou-se, inicialmente, a um levantamento bibliográfico, para, na sequência, analisar o conteúdo de três estudos interrelacionados, envolvendo formação docente, análise de habilidades do funcionamento executivo e das práticas pedagógicas. Os resultados sugerem que desafiar habilidades para a aprendizagem de uma criança pode implicar a sua capacidade em lidar com situações adversas dos ambientes vulneráveis, o que, por sua vez, pode modificar sua trajetória de vida.
Filosofia trágica e pedagogia da escolha: imaginários cinematográficos sobre a afirmação da vida
Authors: Almeida Rogério de
Published: April 2023

Resumo O vínculo entre a filosofia trágica (nada, acaso e convenção) e a afirmação da vida ( amor fati ), como estabelecido por Friedrich Nietzsche e Clément Rosset, é estudado neste artigo sob o método do perspectivismo hermenêutico e em diálogo com os filmes Lucky (2017), dirigido por John Carroll Lynch, Paterson (2016), de Jim Jarmush, e A árvore dos frutos selvagens (2018), de Nuri Bilge Ceylan. Os imaginários dessas três obras cinematográficas traduzem um processo de reflexão sobre a vida que culmina na aprovação trágica, revelada a partir da trajetória dos protagonistas e do caráter formativo de suas experiências, cujo saber ( páthei mathos ) conflui com a pedagogia da escolha em seus três movimentos: a suspensão da crença, pela qual se estabelece o jogo estético que permite ver o mundo por outra perspectiva; a estética da experiência, que valoriza o saber exercitado pelas obras de ficção; e, por fim, a constituição de itinerários de (auto)formação, que organizam as experiências formativas e possibilitam a escolha da afirmação trágica. As conclusões apontam que, em consonância com a continuidade da vida dos protagonistas dos filmes estudados, a afirmação incondicional da vida não é o resultado, a etapa final de uma escolha, mas um processo contínuo de aprovação, desde que se reconheça o caráter trágico da existência, do que é dado a viver.
INTERLAMINAR ENDOSCOPIC LUMBAR DISCECTOMY - CLINICAL OUTCOME
Authors: Bonafim Renato Márcio Souza , Kulcheski Álynson Larocca , Sebben André Luís , Santoro Pedro Grein Del , Benato Marcel Luiz , Graells Xavier Soler I
Published: April 2023

ABSTRACT Objective: Evaluate the clinical outcome of patients with lumbar disc herniation (HDL) operated by endoscopic interlaminar microdiscectomy. We evaluated epidemiology, time to return to work, and technique-related complications as secondary outcomes. Method: Prospective longitudinal study, where patients with HDL with surgical indications were evaluated. They underwent endoscopic discectomy exclusively using the interlaminar technique. Clinical results were evaluated using the Oswestry 2.0 questionnaire (ODI) and the visual analog scale (VAS). In this study, we inserted the Macnab postoperative satisfaction index. In parallel with these indices, we analyzed the results regarding epidemiology variables, time to return to work, and complications. Such questionnaires were applied preoperatively, postoperatively the day after surgery, and one year after. Results: In 132 patients selected for the study, we obtained significant clinical improvement in the ODI and VAS questionnaires, and 81.3% of the patients had excellent and good Macnab index. The hospital stay was 22.7 hours, and the return to work was 30 days. The rate of complications with the method was 12.8%, with recurrence of disc herniation being the most common complication with 9.8% of cases. Conclusion: The endoscopic technique proved effective in treating lumbar spinal disc herniation with significant clinical improvement in the analyzed period, low incidence of complications, early postoperative rehabilitation, and results close to or superior to the gold standard technique. Level of Evidence III; Prospective cohort study
QUALITY OF LIFE ANALYSIS ON PATIENTS AFTER ARTHROPLASTY OR LUMBAR ARTHRODESIS
Authors: Silva Gustavo Morais da , Rodrigues Luciano Miller Reis , Lopes Fernanda Amate , Cesar André Evaristo Marcondes
Published: April 2023

ABSTRACT Objective: To perform a retrospective analysis of patients with degenerative disc disease of the lumbar spine undergoing arthrodesis or lumbar arthroplasty in terms of functional capacity and quality of life. Methods: Retrospective observational study analyzing the medical records of patients undergoing arthrodesis or lumbar arthroplasty, followed-up at an outpatient clinic from 2018 to 2020. Patient characteristics were evaluated; the quality of life through the results of the Short Form 36 Health Survey Questionnaire (SF-36) and the functional capacity using the Oswestry Disability Index (ODI) in the pre-surgical and post-surgical periods (6 months, 1 and 2 years). The criterion to establish statistical significance was p≤0.05. Results: Sixty-one patients were evaluated. After the surgical interventions, the individuals migrated from the classification of invalid (61.4%-64.6%) to minimal/moderate disability (17.7%-25.6%). There was a decline in ODI scores over time of follow-up (p≤0.001) as well as in SF-36 values (p≤0.001) for all surgical techniques. In this regard, evaluating the difference in means revealed the better performance of lumbar arthroplasty (p≤0.001). Conclusion: The data suggest that lumbar arthroplasty offers greater benefits to patients regarding functional capacity and quality of life. Level of Evidence III; Retrospective, descriptive, observational study.
MORPHOMETRIC ANALYSIS OF THE SURGICAL CORRIDOR IN THE PRE-PSOAS APPROACH: AN MRI STUDY IN THE BRAZILIAN POPULATION
Authors: Lacerda Gabriel Carvalho , Tatis Guillermo Julio , Raymundo Miguel Lozano , Andrade Luciene Mota , Menezes Cristiano Magalhães
Published: April 2023

ABSTRACT Objective: This study aims to perform a morphometric analysis and explore the characteristics of the surgical corridor of the anterior to psoas approach in the Brazilian population through magnetic resonance imaging (MRI). Methods: Two hundred spinal MRI scans of patients aged between 18 and 80 years were evaluated using axial cuts at L2-L5 levels and a sagittal cut, T2 weighted. The relationship between the left psoas muscle and the abdominal aorta or the left common iliac artery was analyzed. The anterior to psoas corridor was defined as the shortest distance between the posterolateral aspect of the aorta or inferior vena cava or the nearest iliac vessel and the anteromedial aspect of the ipsilateral psoas muscle. Results: 104 females and 96 males with a mean age of 49,68±2.04 (range 18–80) years. The mean anterior to psoas distance at the L2-L3 level was 14,17±0.75mm; at the L3-L4 level was 12,08±0.77m,m and at the L4-L5 level was 9,12±0.77mm. The surgical corridors at all levels were larger in the older population. Conclusion: In most Brazilian patients, the anterior to psoas approach can be a good alternative for lumbar intervertebral fusions. As a routine in preoperative examination and surgical planning, lumbar MRI is fundamental in preoperative evaluation for anterior to psoas approach surgery. Level of Evidence IV; Descriptive study.
Design of lead-rubber-bearing isolation systems using a grasshopper optimisation algorithm
Authors: Mollaei Somayeh , Farsangi Ehsan Noroozinejad , Babaei Mehdi , Mehri Fatemeh , Ghahramani Fakhraddin
Published: April 2023

Seismic isolation is an efficient method for improving the seismic behaviour of building structures. Sensitivity analysis of the behaviour of base-isolated structures is essential for investigating the effects of various mechanical and environmental factors on the performance of seismic isolation systems. In this study, the optimal design of a lead-rubber-bearing seismic isolation system was investigated by considering irregular mass conditions and near-fault seismic excitation. The grasshopper optimisation algorithm was used to optimise the design of the isolation system. Sensitivity analysis of the seismic response of the isolated structures was carried out for the mechanical parameters of the isolation system, mass irregularity in the building and near-fault earthquakes. The results proved the efficiency of the algorithm in optimal design problems for structural isolation systems. Also, the sensitivity analysis of the seismic behaviour of base-isolated structures showed that the yield base shear index had the most important effects in analysis. Furthermore, mass irregularity showed a negligible influence on the behaviour of the isolated structures.
Effect of mineralogy on grindability -A case study of copper ores
Authors: Nghipulile T. , Moongo T.E. , Dzinomwa G. , Maweja K. , Mapani B. , Kurasha J. , Amwaama M.
Published: April 2023

The effect of mineralogy on the grindability was investigated using three copper ores - two sulphides and one oxide. The dominant copper minerals were identified by optical microscopy and mineral chemistry derived from SEM-EDS analysis. The sample designated sulphide 1 was bornite-rich, sulphide 2 ore was mainly chalcopyrite, and the oxide ore was predominantly malachite and minor azurite. The gangue minerals were identified using semi-qualitative XRD analysis. Sulphide 1 contained more than 80% (w/w) of quartz compared to about 70% in the other two ores. The Bond work indices were 13.8, 21.6, and 17.3 kWh/t for sulphide 1, sulphide 2, and oxide ore respectively. This suggested that the chalcopyrite-rich ore is the hardest, while the malachite-rich ore has intermediate hardness, and the bornite-rich ore is the softest. The brittleness indices of the ores were calculated using the chemical composition of the gangue, and a good correlation between brittleness indices and Bond work indices was observed, which highlights the importance of the gangue composition in determining the fracture behaviour of the ores. There is scope for further investigation into the relationship between ore mineralogy and comminution behaviour using other breakage characterization techniques.
Cell culture and Western blot v1
Authors: Dickey Andrea , not provided rabrisch
Published: April 2023

Protocol for detecting Rab7a phosphorylation at S72 by LRRK1 and LRRK1 mutants in HEK 293T cells.
Skin Biopsy Protocol (Mammals): Non-lethal Sampling v2
Authors: not provided sanaz.arenivas
Published: April 2023

Version date: April 2023 The following protocol illustrates how to collect and ship living tissue from a mammalian species under field conditions for long-term cryopreservation. Skin tissues are optimal for harvesting live fibroblast cells that can either be immediately cryobanked at -196°C, or processed for cell culture and later cryobanked at -196°C. To print this protocol: Click the arrow to the right of the "MORE" button at the top of this page and select the option to print or download as PDF version. References: Coyner, K.S. (2011). Skills Laboratory: How to perform a skin biopsy. DVM306. https://www.dvm360.com/view/skills-laboratory-how-perform-skin-biopsy Hackworth, C. (2021). Skin Punch Biopsy: An overview for the Veterinary Nurse. Kansas State Veterinary Diagnostic Laboratory. https://www.ksvdl.org/resources/news/diagnostic_insights_for_technicians/august2019/skin-punch-biopsy.html Houck, M. L., Lear, T. L., & Charter, S. J. (2017). Animal cytogenetics. In The AGT Cytogenetics Laboratory Manual (pp. 1055–1102). https://doi.org/10.1002/9781119061199.ch24 Trans Ova Genetics. (2022). Trans Ova Livestock Cloning. https://transova.com/service/cloning-services/ ViaGen Pets & Equine. (2021). Emergency Pets Protocol – U.S. Clients. https://www.viagenpets.com/emergency-pets/ White, C. L., & Dusek, R. J. (2015). Wildlife specimen collection, preservation, and shipment. In J. C. Franson, M. Friend, S. E. J. Gibbs, & M. A. Wild (Eds.), Techniques and Methods. US Geological Survey. https://doi.org/10.3133/tm15c4
Enriching Pre-service Teacher Education with Keeping Learning Journals
Authors: Karataş Faik Özgür , Cengiz Canan , Çelik Suat
Published: April 2023

Investigating the integration of learning journals into a pre-service teacher education course to promote reflection was the overall goal of this study. Studies about evaluating students’ journals have generally analyzed them using a holistic and general approach without examining their content and levels of reflection. This study focuses on both contents, levels of reflection, and their relationship. The participants of the study consisted of 33 senior pre-service elementary teachers. The participants were asked to produce a learning journal entry each week at the end of the Science, Technology, Society, and Environment class, in which they were asked to reflect on what they had learned. A deductive content analysis was utilized to determine the levels of reflection of the pre-service teachers’ journals. Deductive content analysis was used to determine the levels of reflection of the pre-service teachers’ journals. The levels of reflection of the participants were moderate and did not show a pattern of improvement over time; instead, the levels of reflection depended on the content of the related class meeting. The majority of the participants agreed that keeping learning journals improved their self-expression and self-assessment skills and retention. The feedback cycle should be reconsidered for further improvement in the journals.
Making Yogurt: A Practical Study to Develop an Understanding of Useful Bacteria
Authors: Üçüncü Gökşen , Karakaya Ferhat , Yilmaz Mehmet
Published: April 2023

This study aims for students to comprehend the beneficial functions of bacteria with the traditional home yogurt leavening activity. Also, it aims to identify alternative concepts related to leavening and contribute to students' home yogurt consumption habits. The study is a case study. The study was conducted with 29 fifth-grade students studying at a public school in Istanbul in the 2019-2020 academic year and their parents. Questionnaire forms and student observation forms developed by the researchers were used as data collection tools. The obtained data were described by content analysis. Before the application, the participant students were given these three statements; microbes as a sample of microscopic creatures, yeast fungi caused yogurt formation, and yogurt is healthy because it was a dairy product. While after the application, participant students changed their statements to these three; the term microbe was not used as a sample of microscopic creatures, bacteria took part in the formation of yogurt, and yogurt is healthy because it contains microscopic creatures beneficial for the digestive system. The educational activities integrated into daily life contribute to students' conceptual learning.
Determining the Cognitive Structures of Secondary School Students on COVID-19
Authors: Çıngıl Barış Çiğdem
Published: April 2023

This research aims to determine the cognitive structures of secondary school students about COVID-19. In this research, a case study, one of the qualitative research methods, was used, and demographic information and a word association test were the data sources. The study group of the research consists of 226 students who continue their education in the 6th and 7th grades of a public secondary school. The data were collected via Google Form, and the obtained data were analyzed by content analysis. The cognitive structures of secondary school students on the concept of COVID-19 are grouped under 11 categories. These categories are COVID-19 Prevention Methods, COVID-19 Reflections in Press, COVID-19 Results, COVID-19 Perceptions, Causes of COVID-19 Transmission, COVID-19 Treatment, COVID-19 Symptoms, Countries where COVID-19 are Common, Characteristics of COVID-19, COVID-19 Carriers and COVID-19 Diagnostic Ways. When these categories were examined, it was seen that the students' cognitive structures about the concept of COVID-19 focused on COVID-19 Prevention Methods, COVID-19 Reflections in Press, COVID-19 Results, and COVID-19 Perceptions. In addition, it has been determined that some students have misconceptions about the COVID-19 virus.
The Effect of Engineering Design-based STEM Activities on the Refugee Students’ Sense of School Belonging
Authors: Yalçın Sema Altun , Günsel Şeyma Güvenç , Çakır Zehra
Published: April 2023

In the research, the effect of engineering design-based STEM activities on the school belonging to seventh-grade refugee students was examined. A mixed-method was used in the research. The research sample consists of 32 Syrian refugee students studying in the 7th grade in the fall semester of the 2019-2020 academic year. The study lasted for ten weeks, with two lessons per week. In addition, the “School Attachment Scale for Children and Adolescents” was used as a quantitative data collection tool. On the other hand, qualitative data collection tools were used as “STEM Education Reflective Diary Form, STEM Education Interview Form, and Teacher Interview Form,” which were prepared based on quantitative scale items. Statistical methods were used to analyze the quantitative data obtained in the research, and content analysis was used in the qualitative data analysis. The quantitative data showed a significant difference between the pre-test and post-test scores. As a result, It was concluded that the engineering design-based STEM activities carried out contributed positively to the individual and social development of Syrian refugee students; their positive attitudes towards the lesson and the teacher impacted their sense of belonging to the school.
Comportamiento y estados de ánimo relacionados con el consumo de sustancias psicoactivas
Authors: Ríos Flórez Jorge Alexander , Jiménez-Tabares Jey Sebastián , Marín-Moreno Brandon Steven , Chalarca-Marulanda Andrea Salomé
Published: April 2023

Este estudio tuvo como propósito caracterizar el comportamiento y los estados de ánimo de consumidores de sustancias psicoactivas en comparación con no consumidores, identificando la relación existente entre los estados de ánimo, la conducta suicida, la violencia y los comportamientos agresivos. Se formuló como una investigación transversal, de enfoque cuantitativo y con un diseño de análisis comparativo-correlacional. La selección de la muestra se realizó por modelo no probabilístico. Participaron 4237 personas, entre consumidores y no consumidores de sustancias psicoactivas (spa) (ilegales). Se emplearon los inventarios de ansiedad y de depresión de Beck, una escala de valoración subjetiva del estado de ánimo, y el registro de una historia socioclínica. Se halló relación entre el consumo de sustancias psicoactivas y la presencia de comportamientos negativos característicos de agresividad, e ideación y conductas suicidas. Sin embargo, los consumidores han sufrido menos bullying escolar y laboral. Asimismo, los consumidores de sustancias psicoactivas atribuyen, por autopercepción, mayores niveles de ansiedad y depresión, a sus estados de ánimo, en relación con los no consumidores. Se encontró coherencia con la presencia objetiva de sintomatología característica de ansiedad y depresión; reconociendo acertadamente sus estados de ánimo. Usuarios de spa suelen consumir en mayor medida medicamentos para el control del sueño y los estados de ánimo, y asisten con más frecuencia a consulta psicológica.
Prediction of recital characteristics of a CI diesel engine operated by bio-fuel extracts from cotton seed oil, linseed oil and mahua seed oil using ANN metho
Authors: REDDY KUNDURU Srinivasa , YARRAPATHRUNI VENKATA Hanumantha Rao , VALLAPUDI Dhanaraju , DEENADAYALAN Narmatha , KUMARAVEL Arul Raj
Published: April 2023

In the wide survey, it is explored that the potential of artificial neural network is used to foretell the recital (performance) characteristics of a four stroke single cylinder diesel engine using the biofuel obtained from cottonseed, linseed and Mahua seed. The test engine was powered with diesel and biofuel with its blends from cotton seed, linseed and Mahua seed separately. Experimental results of the cotton seed oil, linseed oil and mahua oil as a substitute for diesel revealed that linseed oil provides the better engine performance nearly equal to diesel. The ANN is used to compute the performance characteristics such as Indicated power, Brake power, Friction power, Thermal efficiency, brake mean effective pressure, brake thermal efficiency, Brake specific fuel consumption, Indicated thermal efficiency, indicated mean effective pressure, Mechanical efficiency, Indicated specific fuel consumption, volumetric efficiency and combustion characteristics as compression ratio at different conditions of torque, speed, water flow , air rate and fuel rate. An ANN sculpt was developed with 80% of training data and 20% of testing data from experimental values. In this model, back propagation feed forward neural network with five inputs and eleven outputs has been used. The ANN model result accuracy was found to agree nearly with the experimental results with the regression coefficient value approximately equal to one and low mean square error value. Thus, the proposed ANN model was legitimate tool for predicting the combustion and performance of diesel engine.
A Formação do Pedagogo na Modalidade a Distância: Reconfigurações em Tempos de Pandemia
Authors: Marcon Karina , Goedert Lidiane
Published: April 2023

Este artigo socializa os dados de uma pesquisa diagnóstica realizada com estudantes e equipe docente (professores e tutores) do curso de Pedagogia na modalidade a distância do Centro de Educação a Distância da Universidade do Estado de Santa Catarina (CEAD/UDESC), desenvolvida por meio de um questionário online tipo survey que teve a finalidade de identificar o acesso às tecnologias digitais de rede e à internet pelos estudantes e equipe docente do curso, para organizar e retomar as atividades de ensino que haviam sido interrompidas em função da Pandemia de Covid-19. Nesse sentido, enquanto gestão do curso de Pedagogia, buscamos mapear o acesso à infraestrutura tecnológica e levantar as dificuldades encontradas por eles neste processo. Sendo assim, neste texto sinalizamos as mudanças implementadas ao longo do ano de 2020, os encaminhamentos para a retomada das atividades de ensino e o acompanhamento realizado ao longo do ano, bem como as considerações da gestão sobre as mudanças ocorridas a partir do diagnóstico realizado. Os resultados evidenciam que a pandemia alterou a rotina de estudos e de outras dimensões do cotidiano das pessoas; apressou processos de inclusão digital; que os agentes educativos do curso de Pedagogia analisado sofreram com dificuldades de acesso à internet, falta de equipamentos ou com um acesso com baixa qualidade de conexão, além de demonstrar a necessidade de formação continuada pelos estudantes e equipe docente do curso.
 
Palavras-chave: Educação a distância. Pandemia. Pedagogia. Formação de professores.
DIAGNOSTIC SIGNIFICANCE OF COAGULOGRAM PARAMETERS FOR ASSESSMENT OF STRESS CONDITIONS IN EXPERIMENTAL STRESS MODEL CONDITIONS OF CARP (CYPRINUS CARPIO) AND TILAPIA (OREOCHROMIS NILOTICUS)
Authors:   FSBEI HE Vologda State Dairy Academy, Berezina D.I. , Fomina L.L. ,   FSBEI HE Vologda State Dairy Academy, A.V. Ryzhakov ,   FSBEI HE Vologda State Dairy Academy
Published: April 2023

The paper presents research results of reaction of some parameters of secondary hemostasis of commercial fish - carp Cyprinus carpio and tilapia Oreochromis niloticus to stress of various durations induced by corticosteroids (dexamethasone and betamethasone). The purpose of the work was to determine the earliest changing coagulogram parameters of fish under conditions of experimental stress model and to assess the suitability of these parameters for early diagnosis of stress reactions. The study was carried out in Vologda region, the fish were divided into three groups: fish with chronic stress, with acute stress and control animals, their blood was taken by puncture of the tail vein before hormone treatment, and then 7 and 21 days after. The following changes in coagulogram parameters were studied: thrombin time (TT), prothrombin time (PT), activated partial thromboplastin time (APTT), concentration of fibrinogen and soluble fibrin-monomer complexes (SFMC), antithrombin III. It was found that the level of plasma fibrinogen, the concentration of which is directly proportional to stress duration is the earliest and the most explicitly reacting to stress influence for carps. As far as tilapia is concerned, many parameters of hemostasis were more sensitive to the effects of prolonged stress compared to controls: a decrease of APTT, PT, fibrinogen concentration, and an increase of SFMC. These parameters can be determined as markers (bioindicators) of development of stress conditions in these fish species.
CLINICAL AND MORPHOLOGICAL SUBSTANTIATION OF INTRANASAL LYMPHOMAS OF CATS
Authors:   FSBEI HE Moscow State University of Food Production, Melikova Yu.N. , Sotnikova L.F. ,   FSBEI HE Moscow State University of Food Production
Published: April 2023

The article discusses results of the research on intranasal lymphoma spread of cats, based on the study of 38 clinical cases of animals with lesions of the nasal cavity at the age of 5 months to 18 years with clinical symptoms from the total number (N=4937) of cats. The research was conducted at the Department of Diseases of Small Domestic, Laboratory and Exotic animals of FSBEI HE "Moscow State University of Food Production" and the veterinary clinic "Zoogalereya", Moscow. Intranasal neoplasms are rare for cats. Of all nasal oncopathies, lymphomas are most common in animals of the middle age group and, according to the literature data, take up to 1% of all tumors of cats. Endogenous and exogenous factors that cause tumors of cats’ nasal cavity are diverse. If intranasal pathology is suspected, it is necessary to adhere to the plan of diagnostic manipulations, because the first clinical symptoms of the process are the same for lesions of a different nature. For diagnosis and specification of the clinical stage of the disease, it is necessary to conduct a series of diagnostic studies, including radiography, MRI and CT, aimed at determining the localization of the pathology, spread, degree of invasion and degree of involvement of blood vessels in a specific oncological process. Such diagnostic methods as palpation of regional lymph nodes, chest radiographs and ultrasonography of the abdominal organs are aimed at determining the clinical stage of oncopathologies. The most predisposed to occurrence of intranasal lymphomas was a group of cats aged 5-9 years. Gender and breed susceptibility was not revealed. In case of nasal cavity pathologies of cats, a common symptom is shortness of breath, lack of patency of nasal passages, which appears at later stages of the disease. Nasal discharge and epistaxis are rare, convulsive seizures - when the tumor invades via the ethmoid bone. The predominance of unilateral over bilateral discharge was noted as the most common symptom, 39.4%, while the nature of the discharge may be different. Sneezing occurred in 13.2%, coughing in 5.2% of cases. Deformation of the facial part of the skull was observed in 28.9% of cats, epistaxis, lacrimation and atony - in 13.2% of cases, 5.2% of cats had neurological symptoms.
LACTATION FUNCTION OF FIRST-CALF HEIFERS OF HOLSTEIN BREED OF DIFFERENT ECOGENESIS IN THE CONDITIONS OF INTENSIVE TECHNOLOGY
Authors:   FSBEI HE Voronezh State Agrarian University named after Emperor Peter I, Khromova L. G. , Miroshina S. E. ,   FSBEI HE Voronezh State Agrarian University named after Emperor Peter I
Published: April 2023

The largest contribution to milk production increase is made by large highly-technological complexes, occupied by animals of the Holstein breed, imported from Western European countries. It currently accounts for 26.47% in the dairy herd structure of the Russian Federation. In this regard, it is necessary to study milk productivity, quality characteristics and safety of Holstein cows’ milk produced in the conditions of industrial technology, which is the purpose of our research. The scientific experiment was carried out in the conditions of OOO Agroindustrial Complex Rus, the largest milk producer in Ryazan region. As a result, high milk productivity of first-calf heifers of Holstein breed, imported from the Netherlands, Hungary and own reproduction under intensive technology, was established. There are no significant differences in production of specified lactation. The milk of cows of the studied genotypes had a high concentration of dry matter and calorie content, as for the content of somatic cells, it met the established requirements of the European and national standards. The content of minor components of milk indicated the absence of ketosis (β-hydroxybutyric acid, acetone) and compliance of energy and protein in the diets of cows (urea). The highest realization level of PIC (parent index of cow) for milk yield was shown by first-calf heifers of domestic selection, as the most adapted to local conditions, and the lowest - analogues imported from the Netherlands, with the highest PIC for milk yield. Their realization level of productive potential of milk yield was lower compared to the first-calf heifers of Hungarian and domestic selection, respectively, by 14.8 (P<0.001) and 20.1% (P<0.001), the coefficient of lactation curve stability is less than in comparison with domestic peers by 2.3 (Р<0.01), and imported from Hungary by 1.3 (Р>0.05), which shows that the housing conditions do not correspond to biological status of the first heifers imported from the Netherlands.
RESEARCH ON THE INFLUENCE OF ORGANIC AND MINERAL FERTILIZERS ON RAPESEED YIELD AND ASH COMPOSITION OF ITS OIL SEEDS
Authors:   Federal State Budgetary Educational Institution of Higher Education ", Zubkova T.V. ,   Elets State University named after I. A. Bunin", Motyleva S.M. ,   2All-Russian Selection and Technological Institute of Horticulture and Nursery Gardens of the Russian Agricultural Academy, Vinogradov D.V. ,   3Federal State Budgetary Educational Institution of Higher Education “Ryazan State Agrotechnological University named after P.A. Kostychev
Published: April 2023

The article presents results of a field experiment with application of mineral (NPK and zeolite) and organic fertilizers in the technology of spring rapeseed cultivation, as well as a comparative analysis of the ash composition of rape seeds of Rif variety, depending on the variants of the research. Six variants were studied: growing plants without fertilization (control); mineral fertilizer N60: P60: K60 alone and in combination with zeolite (5 t/ha); pure zeolite (5 t/ha); chicken manure (5 t/ha) alone and in combination with zeolite (5 t/ha). Accumulation of nine main elements (wt., %) contained in the ash of spring rapeseed seeds was studied by the method of energy dispersive spectrometry (X-Ray-analysis). The order of element accumulation was determined: P ≈ K>Mg ≥ Ca>Mo> S>Zn>Mn>Fe. The proportion of P is from 10.852 to 11.855 wt. %; the proportion of K is from 9.933 to 12.343 wt.%; Mg, Ca and Mo are present in rape seeds in similar concentrations within 4.0 -5.8 wt.%. Mutual usage of zeolite and organic fertilizer provided an increase of mineral accumulation in the seeds. Correlations between the elements were established. Higher level of macro- and microelements in seeds, necessary for humans, brings about good perspectives to create functional products based on the studied rape seeds for food enrichment. Positive effect of combined organo-mineral fertilizers on accumulation of mineral substances in rape seeds was established.
PHENOMENON OF TRANSGRESSION VARIABILITY IN POPULATIONS OF VARIOUS TYPES OF HEMP INTERVARIETAL HYBRIDS
Authors:   FSBEI HE Chuvash State Agrarian University, Dimitriev V.L. , Shashkarov L.G. ,   FSBEI HE Chuvash State Agrarian University, Lozhkin A.G. ,   FSBEI HE Chuvash State Agrarian University
Published: April 2023

The article deals with the issues of the phenomenon of transgression variability in populations of various types of hemp intervarietal hybrids. The study of the first generation of various types of intervarietal hemp hybrids showed that transgression trait is observed in most traits available for study. Studies showed that the height of intervarietal hemp hybrid plants transgresses within a fairly wide range, depending on the types of crossing. Concurrently, the genotypes of parental components have a great influence on the degree and frequency of tall and short-stemmed plants. So, in case of direct crossing of forms close in plant height (Glukhovskaya-10 and Odnodomnaya-2, YUS-9 and Poltavskaya-3), a population with biotypes exceeding the best parent by 18-19% is created in the offspring. The occurrence of such plants in this case is significant (12-16%). Crossing of components that differ greatly in plant height (YUS-9 and Odnodomnaya-2, Glukhovskaya-10 and Poltavskaya-3) shows a degree of transgression of 13-14% and a frequency of 9-10%. There is a transgression of some productivity elements in populations of various types of intervarietal hemp hybrids. The highest rates of transgression are revealed by the stem weight of one plant. The splitting nature of the first generation of simple intervarietal hybrids depends on the genotypes of the parental forms. Thus, when crossing Glukhovskaya-10 and Odnodomnaya-2 varieties, which are identical in stem weight, a population of biotypes, exceeding the best parent by 25% is created. The occurrence of such plants in this case is significant (24%). When crossing forms of YUS-9 and Odnoedomnaya-2, contrasting in stem weight, the degree of transgression is 18%, and the frequency is 15%. Transgression practically does not occur in the offspring of backcross hybrids. Therefore, the best biotypes in terms of a complex of traits, isolated in the offspring of first-generation hybrids, should be used to obtain complex hybrid populations. Complex hybrid populations are a valuable source material and can be the parent of a variety.
β-catenin promotes resistance to trastuzumab in breast cance
Authors: Hao Xiaoyan , Zheng Jialu , Yu Xiaoqin , Li Zhixin , Ren Guanghui
Published: April 2023

More than 1 million women worldwide are diagnosed with breast cancer (BC) each year. This study aims to explore the molecular mechanisms of β-catenin affecting the trastuzumab tolerance in HER2-positive BC. β-catenin in BC and non-BC tissue samples were assessed by immunohistochemistry. β-catenin and HER2 were over-expressed and knockdown to evaluate their role in tumorigenicity and trastuzumab resistance in cell and animal models using soft-agar and xenograft assays. Confocal laser immunofluorescence assay and co-immunoprecipitation were used to assess protein-protein binding. Expression of genes was detected using Western blot analysis. β-catenin was highly expressed in primary and metastatic BC, overexpression of β-catenin increased the colony formation of MCF7 cells when it was co-expressed with HER2 and synergically increased the tumor size in immunodeficient mice. Overexpression of β-catenin also increased the phosphorylation of HER2 and HER3 and increased the size of tumor derived from HER2-elevated cells. Confocal laser immunofluorescence assay showed that β-catenin and HER2 were co-localized on the membrane of MDA-MB-231 cells, suggesting that β-catenin binds HER2 to activate the HER2 signaling pathway. Immunoprecipitation of β-catenin and HER2 also confirmed this binding. On the other hand, knockdown of β-catenin in MDA-MB-231 cell lines decreased the activity of SRC and decreased phosphorylation of HER2 at Y877 and Y1248. The interaction between HER2 and SRC was enhanced when β-catenin was overexpressed, and β-catenin increased the resistance of tumor derived from HER2 elevated BT474 cells to trastuzumab. Further analysis showed that trastuzumab inhibited the activation of HER3, but SRC was still highly expressed in cells overexpressing β-catenin. Our work demonstrates that β-catenin is highly expressed in BC and it synergically promotes formation and progress of BC with HER2. β-catenin binds with HER2 leading to enhanced interaction with SRC and resistance to trastuzumab.
Gladiadoras de Saias: mulheres capoeiras no norte do Brasil (1876 a 1912)
Authors: Leal Luiz Augusto Pinheiro
Published: April 2023

Luiz Augusto Pinheiro Leal ? Doutor em Estudos Étnicos e Africanos. Professor Adjunto IV da Universidade Federal do Pará/Faculdade de História do Campus Universitário do Tocantins/Cametá.
Entre Tecidos e Adornos: a moda das mulheres das camadas populares na Belém da Belle Époque (1870-1912)
Authors: Teixeira Amanda Gatinho
Published: April 2023

O presente artigo discute a moda – vestimentas e adornos – das mulheres pertencentes às camadas populares na Belém da Belle Époque (1870-1912) a partir das representações iniciais de David O. Widhopff e João Affonso, denominada de A Mulata Paraense. A investigação também se dá por meio de relatos de viajantes e representações de obras pictóricas, tanto as que antecedem como as que sucedem o recorte temporal do objeto de estudo, tendo em vista que tais registros revelam especificidades acerca dos modos de vestir e de adornar dessas mulheres. Através dessas fontes, permitiu-se entender que estas mulheres elegeram a moda como linguagem de expressão de suas crenças, gostos e costumes, configurando em uma representação emblemática, a qual ainda está presente no imaginário da população local.
Crise Covid-19 e Trabalho: Um olhar sobre a desigualdade de gênero na ciência
Authors: Amaral Ivanete Modesto do
Published: April 2023

Este artigo discute a desigualdade de gênero na ciência através de relatos de mulheres cientistas em diferentes áreas de atuação no Brasil, entrevistadas por órgãos de pesquisas, em 2020. As profissionais falaram como estão suas ocupações no mercado de trabalho e os principais obstáculos nesse momento de pandemia da Covid-19. Fundamentando-se na categoria da “divisão sexual do trabalho” e complementando com os dados levantados pelo movimento Parent in Science, concluiu-se que, mesmo com suas qualificações e experiências profissionais, as mulheres enfrentam questões decorrentes do predomínio de práticas patriarcais na sociedade brasileira, diante da difícil articulação entre o trabalho profissional e o trabalho doméstico no período de isolamento social.
Direitos Humanos das Mulheres e Controle da Atividade Estatal: o caso Maria Da Penha
Authors: Souza Luanna Tomaz de
Published: April 2023

Este artigo pretende refletir acerca dos mecanismos de controle da atividade estatal no âmbito dos direitos humanos das mulheres à luz do Caso Maria da Penha. A denúncia deste caso à Comissão Interamericana de Direitos Humanos da Organização dos Estados Americanos (CIDH) trouxe inúmeros reflexos para o enfrentamento da violência conjugal, inclusive dando ensejo à promulgação, no Brasil, de uma lei específica para tratar da violência doméstica e familiar cometida contra a mulher, a Lei nº 11.340/2006. Através dele é possível refletir acerca das políticas públicas desenvolvidas no Brasil em torno da questão, seus limites e os desafios a superar.
Gênero e Desigualdade: a divisão sexual do trabalho e a atuação da mulher na vida pública
Authors: Pereira Erica Patrícia Martel , Soares Ana Cristina De Paula Maués , Silva David Junior De Souza
Published: April 2023

O objetivo deste trabalho é propor uma reflexão acerca da realidade que as mulheres enfrentam ao buscarem o mercado de trabalho, levando em conta o efeito da dupla jornada vivenciada por elas, e como isso as afeta no quesito tempo/liberdade. Para isso, buscamos um diálogo com dez funcionárias terceirizadas responsáveis pelo cuidado e limpeza do espaço de uma instituição pública, traçando, através deste diálogo, uma linha de conexão com as teorias discutidas ao longo texto, para compreender as desigualdades e relações de gênero no ambiente de trabalho. Como metodologia, utilizamos um modelo de pesquisa técnica quali-quantitativo, com aplicação de questionários e realização de entrevistas individuais. Foi possível compreender que as demandas que envolvem a luta das mulheres por igualdade na esfera pública e oportunidades laborais justas têm como um de seus principais obstáculos a limitação da liberdade e autonomia das mulheres no espaço privado.
Análise Socioambiental e Relações de Gênero: um estudo na hidrelétrica de Santo Antônio/Rondônia
Authors: Bacinello Edilson , Carvalho Otacílio Moreira de
Published: April 2023

Neste artigo, com base em bibliografia e dados empíricos, são evidenciadas questões socioambientais inerentes à construção da Usina Hidrelétrica de Santo Antônio, em Rondônia, enfatizando-se a importância da correta mensuração dos impactos, que poderão ocorrer com a implantação da hidrelétrica, para atendimento à proposta sustentável do projeto. Também são discutidas as relações de gênero, identificando-se a necessidade de manutenção de políticas que tratam de forma igualitária e isonômica os homens e as mulheres nas empresas, conforme previstas pelas SPM e SEPPIR.
Narrativas Online como Forma de Expressão Política: o compartilhamento de experiências acerca da Lei Maria da Penha na internet
Authors: Sarmento Rayza
Published: April 2023

Este trabalho propôs-se a observar a interação comunicativa entre mulheres de uma rede social na internet construída para discussões sobre a lei brasileira de combate à violência doméstica contra a mulher (Lei Maria da Penha), entendendo tal interação como forma de expressão política sobre um problema coletivo. Utilizou-se a noção de “narrativa” de Iris Young aplicada ao ambiente online e conseguiu-se perceber que, ao narrar suas experiências, essas mulheres conseguem expressar-se politicamente acerca daquilo que as afeta e estabelecer pontes críticas sobre legislação.
Determination of Serum Trace Elements and Oxidative Stress in Bitches with Transmissible Venereal Tumor
Authors: Akkuş T. , Ekici M.
Published: April 2023

Background: This study was conducted to compare the changes in oxidative stress levels with some trace elements in blood serum in healthy bitches and bitches with transmissible venereal tumor (TVT). Methods: A total of 40 bitches were used in the study. According to the genital organ examinations, healthy bitches constituted the control group (n=20) and those with venereal tumors constituted the TVT group (n=20). Total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI) were determined spectrophotometrically. In addition, some serum trace element levels such as magnesium (Mg), manganese (Mn), iron (Fe), copper (Cu), zinc (Zn) and selenium (Se) were measured using an ICP-MS analysis device. Result: The serum Se, Mg and Zn levels were lower in the TVT group compared to the control group (p less than 0.01) and serum Fe and Cu levels were higher in the TVT group than in the control group (p less than 0.01). Serum TOS and OSI levels were higher (p less than 0.001) and serum TAS levels were lower (p less than 0.001) in the TVT group compared to the control group. The study results showed that oxidative stress is high in bitches with TVT, and in parallel with this, changes occur in the amount of certain trace elements that are associated with oxidative stress.
A Stress Management Tool in Nurses: Mindfulness- Based Stress Reduction
Authors: BARIŞ EREN Nadiye
Published: April 2023

Health, which is a state of complete physical, social and spiritual well-being, is under the influence of various stressors. Stress occurs due to the negative effects on the organism physically and mentally. Stress is encountered in every field in our daily life and affects our health negatively. Nurses working in the healthcare field, which is one of the stressful environments, experience intense stress. Therefore, nurses working in such an environment need to use stress management effectively to protect their own health and increase patient care quality and satisfaction. One of these methods is Mindfulness- Based Stress Reduction. The evidence-based program that includes mindfulness meditation, breathwork, basic yoga, and other relaxation methods for 8 weeks. This review will discuss Mindfulness- Based Stress Reduction in nurses.
Baji yoreme emo komparekame emo yorinokki maxtiabareyme: los tres compadres que querían hablar como los yoris
Authors: Rodríguez Villanueva Rosario Melina , Peña Valenzuela Ana Patricia , Ayoki López David
Published: April 2023

En este artículo se presenta el texto yoreme-mayo Baji yoreme emo komparekame emo Yorinokki maxtiabareyme: Los tres compadres que querían hablar como los yoris, en el que se cuenta la historia de tres hablantes monolingües de Yoremnokki, también conocido como la lengua mayo, que son acusados y encarcelados por un crimen que no cometieron. Este texto literario forma parte de una tradición narrativa en la que el humor subraya los conflictos interétnicos entre los yorememayo y los yoris (hombres blancos), específicamente los malentendidos y discriminación lingüísticos. Pero, si bien es cierto que el humor en este chiste, que fue como nos fue contado, acentúa esta competencia interétnica entre los mayos y los yoris, el hablante lo contó para recalcar el rechazo preponderante de los hablantes en Las Culebras hacia la lengua a causa de la discriminación de la que constantemente son víctimas. Por lo que el objetivo de este artículo no es analizar ni resolver problemas sociolingüísticos actuales de los mayos sino describir grosso modo aspectos generales del Yoremnokki y contextualizar estas cuestiones sociolingüísticas para que el lector conozca un poco más sobre la situación actual de este idioma.