bluuebunny/crossref_metadata_2025 huggingface dataset:
PhactorTM – a High Throughput Experimentation Management System
Authors: Cernak Tim , Mahjour Babak
Published: October 2020

High throughput experimentation (HTE) is an increasingly important tool in the study of chemical synthesis. While the hardware for running HTE in the synthesis lab has evolved significantly in recent years, there remains a need for software solutions to navigate data rich experiments. We have developed the software, phactor™, to facilitate the performance and analysis of HTE in a chemical laboratory. phactor™ allows experimentalists to rapidly design arrays of chemical reactions in 24, 96, 384, or 1,536 wellplates. Users can access online reagent data, such as a lab inventory, to populate wells with experiments and produce instructions to perform the screen manually, or with the assistance of a liquid handling robot. After completion of the screen, analytical results can be uploaded for facile evaluation, and to guide the next series of experiments. All chemical data, metadata, and results are stored in a machine-readable format.
Fabrication of Size-Controlled Metallic Nanogaps down to the Sub 3-Nm Level
Authors: Luo Sihai , Mancini Andrea , Berté Rodrigo , Hoff Bård H. , Maier Stefan A. , de Mello John
Published: October 2020

Metallic nanogaps are fundamental components of nanoscale photonic and electronic devices. However, the lack of reproducible high-yield fabrication methods with nanometric control over the gap-size has hindered practical applications. Here, we report a patterning technique based on molecular self-assembly and physical peeling that allows the gap-width to be tuned over the range 3 – 30 nm and enables the fabrication of massively parallel nanogap arrays containing hundreds of millions of ring-shaped nanogaps (RSNs). The method is used here to prepare molecular diodes across sub-3-nm metallic nanogaps and to fabricate visible-light-active plasmonic substrates based on large-area, gold-based RSN arrays. The substrates are applicable to a broad range of optical applications, and are used here as substrates for surface-enhanced Raman spectroscopy (SERS), providing high enhancement factors of up to 3e8 relative to similar, gap-free thin gold films.
A Novel Series of Single-Cluster Catalysts: Transition Metal Trimer Clusters Supported on Graphdiyne
Authors: Liu Jin-Cheng , Xiao Hai , Zhao Xiao-Kun , Zhang Nan-Nan , Liu Yuan , Xing Deng-Hui , Yu Xiaohu , Hu Han-Shi , Li Jun
Published: October 2020

While single-atom catalysts (SACs) have achieved great success in the past decade, their application is potentially limited by the simplistic single-atom active centers, which makes single-cluster catalysts (SCCs) a natural extension. SCCs with precise numbers of atoms and structural configurations possess SAC’s merits, yet have greater potentials for catalyzing complex reactions and/or bulky reactants. Through systematic quantum-chemical studies and computational screening, we report here the rational design of transition metal trimer clusters anchored on graphdiyne as a novel kind of stable SCCs with great potentials for efficient and precise heterogenous catalysis. By investigating their structures and catalytic performance for oxygen reduction reaction, hydrogen evolution reaction, and CO2 reduction reactions, we provide theoretical guidelines for their potential applications as heterogeneous catalysts. These graphdiyne supported SCCs provide an ideal benchmark scaffold for rational design of precise catalysts for industrially important chemical reactions.
UEMtomaton: A Source-Available Platform to Aid in Start-up of Ultrafast Electron Microscopy Labs
Authors: Du Daniel , Reisbick Spencer , Flannigan David
Published: October 2020

We provide here a description of a basic, entry-level method and user interface for automating ultrafast electron microscopy (UEM) experiments. We provide access to the source code and scripts via a GitHub site for ease of implementation or as a starting reference point for those entering or seeking to enter the field. Core instrumentation and physical connections in the UEM lab at Minnesota are described. An application designed and programmed with C++/CLI as Windows Forms in Microsoft Visual Studio - dubbed UEMtomaton - is also presented. It is our hope that this note provides useful insight for current and future UEM researchers.
Explaining Urease Specificity Towards Nickel: A Re-Analysis of Its Proposed Mechanism
Authors: Ferreira Millena Pereira , Castro Caio Bezerra de , Gruenwaldt Cunha Marques Netto Caterina
Published: October 2020

Urease is a binuclear metalloenzyme selective towards nickel, exhibiting a remarkable rate enhancement of the catalytic reaction. The accepted mechanism for urease describes the coordination of urea to both nickel centers in an O,N bridged mode, enabling the attack of the carbonyl by a bridged hydroxide present between the metallic centers. However, the substitution of nickel by other metals significantly reduces urease´s catalytic efficiency. The proposed mechanism cannot explain this difference in activity since it does not follow a rational nucleophilicity scale. After a careful analysis of the literature data on thermodynamics, kinetics, inhibition, and mutations, we verified that by analyzing the mechanism from a diffrent angle, another pathway is most likely occuring. This mechanism can explain urease´s selectivity towards nickel and all the data present in the literature, gathering amost a century of study about urease.
Self-Concept in Immigrant School Children and the Impact of Length of Residence: Evidence from PISA 2015 for Current Educational Practice
Authors: Figueiredo Sandra , Marôco João , Alves Martins Margarida , Nunes Odete
Published: October 2020

Comparative analyses of the Programme for International Student Assessment between immigrant and native students place immigrant students in an unfavourable position in schools, with disadvantageous indicators regarding socioeconomic and professional paths. However, the Programme for International Student Assessment assesses a series of dimensions that involve constructs that have been little studied in the school immigrant population and that relate to self-concept and school adjustment. Based on the Programme for International Student Assessment’s most recent edition, Portugal’s database of 7,325 15-year-old students was analysed. We selected 438 immigrant cases with two objectives: (1) to evaluate the impact of the length of exposure in the host country on three dependent variables of school adjustment: sense of belonging, perceived loneliness and attitudes towards school (expectations of educational and professional opportunities); (2) to evaluate the differences in results for the same dependent variables, but considering the first and second generation of immigrants in Portugal. For the data analysis, sampling weights and plausible values were analysed with the International Database Analyzer. The results show that students who have been in the country for a year or less have greater difficulties and increased significant differences compared to other migrant groups in the referred indices of self-concept and inclusion. However, other groups, especially those with periods of long-term residence between four and five years, also face substantial levels of school maladjustment.
ECOLOGICAL EVALUATION OF STABILITY AND PLASTICITY OF SPRING SOFT WHEAT VARIETIES OF DIFFERENT VARIETY CHANGING PERIODS
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, DAVYDOVA N.V. , KAZACHENKO A.O. , SHIROKOLAVA A.V. , NARDID V.A. , REZEPKIN A.M. , SHAROSHKINA YE.YE. , GRACHEVA A.V. , ROMANOVA YE.S. ,   FITS “Nemchinovka”
Published: October 2020

The paper presents an analysis of spring soft wheat varieties of different periods of variety change according to ecological plasticity and stability when cultivated in different climatic conditions (2014–2019). To increase the yield of spring soft wheat varieties, much attention is paid to the devlopment of high-intensity forms that respond positively to additional investments in agricultural technology. These varieties must also demonstrate high yield stability as well as plasticity in relation to environmental factors – i.e. the ability to form the high yields in wide range of environmental conditions. In the course of the study, the authors carried out an environmental assessment of ten varieties of four major groups by yield in a five-year field experiment. The yield upper limits, as well as an indicator of stress resistance, were estimated. Based on these data, statistical coefficients of their ecological plasticity and stability, as well as the stability variant, were analyzed. The Agatha and Esther spring wheat varieties showed the most responsiveness to the improvement of cultivation conditions. They can be considered the most plastic varieties. The highest stability index was observed in the Radmir, Amir, MIS, Zlata and Lyubava varieties. The most promising among the new spring soft wheat varieties is the Radmira variety, which has the best adaptive potential, which incidentally allows it to form a stable high level of productivity in changeable climatic conditions. Among the varieties of earlier periods, promising cultivars include the Zlata variety. Its high adaptability is comfirmed by its cultivation in 1,2,3,4 and 7 regions of Russia.
MERINO SHEEP BREED RAISED UNDER MOUNTAIN BREEDING SYSTEM
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, MUSALAYEV KH.KH. , ABDULLABEKOV R.A. ,   Federal Agricultural Scientific Center of the Republic of Dagestan “FASC RD”, MAGOMEDOVA P.M.
Published: October 2020

Dagestan is the leading Republic of Russia in terms of the number of sheep and sheep breeding products. The zoned target sheep breed in Dagestan is the Dagestan mountain breed. However, this breed produces thin but non-merino wool. Developing the Merino sheep breed suitable for mountain breeding is an urgent problem. The new Merino sheep breed was developed for the foothill zone of Dagestan, where summer Alpine and winter low-lying pastures are located at a distance of no more than 150 km from each other, and summer Alpine pastures are located at an altitude of up to 3000 meters above sea level. The research and stock breeding work was carried out at the farm production enterprise “Krasniy Oktyabr’”, the Kazbek district, in the period between 2005 and 2019. The work resulted in the development of the Arthlukh Merino sheep breed. (Patent for selection achievement No. 10112 “State Commission of the Russian Federation for Selection Achievement Tests and Protection”). The breed was developed by crossing the Stavropol sheep rams with the Dagestan mountain sheep, with the subsequent improvement of crossbreeds by the Manych Merino breed. A distinctive feature of the new Merino breed from the basic herdmates of the Dagestan Mountain breed is the high live weight, which is 15.3–16.5% higher in different sex and age groups. Besides, the amount of washed wool shorn is 16.2–26.0% higher. The ewes’ wool fineness is 22.9 microns (19.4–23.0) – 64 qualities. That of adult rams amounts to 23.3 microns (19.9–23.3) and has 60 qualities. The difference of the wool fineness on the side and thigh does not exceed one quality. The coat length on the side of ewes is not less than 9.0 cm, rams – 9.5 cm, gimmers (young ewes) – 9.5 cm and replacement rams – 10.0 cm. The wool strength is 7.0 cN/Tex. The belly wool cover is good. The suint is stable, of a white and light cream color. The average yield of washed wool excluding the lowest grades is 64%. The fertility of ewes ranged from 125% to 135%.
Cinsiyete göre dindarlık: bir meta-analiz çalışması
Authors: KORKMAZ Sezai
Published: October 2020

Bu çalışmada cinsiyete göre genel dindarlık, dini inanç boyutu ve dini ibadet boyutunda meta-analiz yapılması amaçlanmıştır. Bu meta-analiz çalışması, Türkiye’de yapılmış olan lisansüstü tezler üzerine yapılmıştır. İlk olarak anahtar kelimeler belirlenip Yök Ulusal Tez Merkezinden tezler incelenmiştir. Dindarlıkla ilgili olan tezler indirilip dâhil etme kriterlerine göre meta-analize giren tezler belirlenmiştir. Dahil etme kriterlerine uyan 18 doktora ve 66 yüksek lisans tezi olmak üzere toplamda 84 tez meta-analize dahil edilmiştir. Ardından meta-analiz istatistik yöntemine bağlı kalınarak kodlama yapılmıştır. Çalışmanın genel dindarlıkta örneklem sayısı erkeklerde 18255 kadınlarda ise 20529, dini inanç boyutunda erkeklerde 4979 kadınlarda 5886, dini ibadet boyutunda ise erkeklerde 5635 kadınlarda 6429 kişidir. Meta-analizde standart ortalama farkı (dini inanç boyutunda ortalama farkı), rassal etki modeli, forest plot ve funnel plot testleri kullanılmıştır. Çalışmada Revman 5 (Review Manager 5) programı aracılığıyla analiz yapılmıştır. Çalışmanın bulgularına göre genel dindarlık, dini inanç boyutu ve dini ibadet boyutunda meta-analizin tüm istatistiki değerlerinin anlamlı olduğu ve heterojen dağılım gösterdiği tespit edilmiştir. Cinsiyete göre genel dindarlık, dini inanç boyutu ve dini ibadet boyutunda kadınların lehine bir durum olduğu tespit edilmiştir. Her üç boyutta da kadınların erkeklerden daha dindar olduğu bulgulanmıştır. Meta-analizde genel dindarlığın etki büyüklüğü -0.11 [-0.15, -0.07], dini inanç boyutunun etki büyüklüğü -0.11 [-0.16, -0.06], dini ibadet boyutunun etki büyüklüğü ise -0.21 [-0.31, -0.11] olarak saptanmıştır. Yapılan meta-analiz çalışmasının tüm boyutlarda heterojen dağılım göstermesi ve istatistiki olarak anlamlı (P<0.00001) olması çalışmanın önemini artırmakta ve ayrıca diğer dindarlık araştırmalarında (ANOVA, korelasyon, regresyon ilişkilerini içeren) meta-analiz çalışmalarının yapılmasını teşvik etmektedir.
Dinî sembollere yönelik psiko-sosyal tutumlar ölçeğinin geliştirilmesi ve bazı değişkenlere göre karşılaştırılması
Authors: GÜLMEZ Çiğdem , PATTABANOĞLU Fatma Zehra
Published: October 2020

Dinî semboller ilk uygarlıklardan günümüze kadar insan yaşamının ayrılmaz unsurlarından birisi olmuştur. Ne var ki günümüz insanının bireysel ve toplumsal yaşamı üzerindeki etkisi bilimsel çalışmalarda henüz açık biçimde ortaya konulmuş değildir. Bu minvalde çalışmanın amacı dinî sembollere yönelik tutumları geçerli ve güvenilir olarak ölçebilen bir ölçme aracını geliştirmek ve bazı demografik değişkenlere göre karşılaştırma yapmaktır. Geliştirilen taslak ölçek ilk olarak Kastamonu Üniversitesinin çeşitli fakültelerinde öğrenim gören 410 öğrenciye uygulanmıştır. Bu örneklemden elde edilen verilerle ölçeğin faktör yapısı açımlayıcı faktör analiziyle belirlenmiş, güvenirlik analizleri yapılmıştır. Toplam 38 maddenin yer aldığı üç alt faktörlü bir ölçek elde edilmiştir. Faktör yapısı belirlenen ölçek yaşları 18-65 arasında değişen 403 kişilik ikinci bir örnekleme uygulanmıştır. Bu örneklemden elde edilen verilere uygulanan doğrulayıcı faktör analizi neticesinde üç faktörlü yapı doğrulanmıştır. Elde edilen uyum indeksleri RMSEA=0,081, NFI = 0,96, NNFI = 0,98, PNFI = 0,90, CFI= 0,98, IFI= 0,98, GFI = 0,87, AGFI= 0,89’dur. Cronbach Alfa katsayısı; 1. boyut için 0,97, ikinci boyut için 0,89 ve üçüncü boyut için 0,84’dir. Ayrıca her bir faktör için ortalama varyans değeri (AVE) ve kompozit güvenirlik (CR) değeri hesaplanmıştır. AVE değerleri faktörler için sırayla 0,62, 0,54 ve 0,58, CR değeri ise sırayla 0,97, 0,89 ve 0,87’dir. Bu sonuçlar ölçeğin ikinci örneklemde yaptığı ölçümün geçerlik ve güvenirliğinin yüksek olduğunu göstermiştir. İlaveten demografik değişkenlere göre dinî sembollere yönelik tutumlar karşılaştırılmıştır. Sonuçlara göre cinsiyet ve eğitim değişkenine göre dinî sembollere yönelik tutumlar farklılık göstermezken, dinî sembolleri tanıma düzeyi, öznel din algısı, yaş ve gelir değişkenleri açısından gruplar arasında anlamlı farklılıklar görülmüştür.
Cis and trans linkage of spin frustrated copper triangles creating Cu6 clusters
Authors: Ali Basharat , Gendron Frédéric , Li Xiao-Lei , Le Guennic Boris , Tang Jinkui
Published: October 2020

Two C3-symmetric guanidine-based copper triangles bridged by acetates in a cis manner and by chloride anions in a trans manner, respectively gave rise to two antiferromagnetically coupled hexanuclear CuII compounds, namely [Cu6L2Cl(μ-OAc)(DMF)3]·DMF (Cu6) and [Cu6L2(μ-Cl)2(DMF)4] (Cu6Cl)(where L stands for fully deprotonated tris (2-hydroxybenzylidene) triaminoguanidinium chloride, H5L). The experimental magnetic data of the two compounds were analyzed theoretically. A relatively good agreement with the experimental data was obtained when using the wavefunction theory (CASSCF) in combination with DFT (B3LYP) calculations for the very strong antiferromagnetic coupling within the Cu3 triangles (Javg = − 300 cm−1 for Cu6 and Javg = − 250 cm−1 for Cu6Cl), leading to spin-frustrated systems. It is worth mentioning that the electronic structure of each CuII center remains very similar in each complex with a Kramers ground state well separated from the first excited state (over 12000 cm−1) and weakly anisotropic (g∥ ≈ 2.40 and g⊥ ≈ 2.10).
EXAMINING THE RELATIONSHIP BETWEEN EMOTIONAL COMPETENCE AND THE CHOSEN PSYCHOLOGICAL CHARACTERISTICS OF TEACHERS IN NORMAL SCHOOLS AND SPECIAL SCHOOLS
Authors: Elamathi K. , Chelvi S.
Published: October 2020

The present study aimed at unraveling the relationship between the trait emotional competence of teachers in normal schools and in special schools and their psychological characteristics mental health, sociability, and emotional wellbeing. The researcher adopted descriptive survey method which enabled her to design her own data collecting instrument for studying emotional competence of teachers and also to make use of suitable sampling technique for identifying the relationship between the dependent and independent variables in a scientific manner. The study has shown that mental health and sociability are the significant correlates of emotional competence of both the categories of teachers. The further analysis revealed that both the psychological correlates have emerged as the significant predictors of the trait emotional competence. The researcher has discussed the implications of the findings at length.
A STUDY ON FAMILY ENVIRONMENT AND ITS EFFECT ON ACADEMIC ACHIEVEMENT IN SCIENCE AMONG SECONDARY SCHOOL STUDENTS
Authors: Pappattu Jasar , Vanitha J.
Published: October 2020

Family environment seems to impact academic performance. Families in common and parents in specific, have often been considered to be the most significant support system obtainable to the child. The toughest factor in molding a child’s character or behavior is the relationship with their parents. Students who have struggled educationally in most circumstances are at higher risk of school avoidance, and eventually dropping out, than those who are effective. For the struggling students, however, school is often a place that only helps to strengthen the low self-esteem. The student attempts to evade these state of mind of failure by staying home. The main motive is to study on family environment and its effect on academic achievement in science. This research is under taken with a view to examining the family environment and its effect on academic achievement in science among secondary school students with a sample size 300 from 8 schools of Palakkad district. Normative Survey method is used. The study concluded that there doesn’t exist any relationship between family environment factors and achievement in science skills among secondary school students.
DEVELOPMENT AND VALIDATION OF TOOL ON PROBLEM SOLVING SKILL FOR HIGH SCHOOL STUDENTS
Authors: Indumathi T. , Ramakrishnan N.
Published: October 2020

In the present study, Problem solving skill scale has been validated for the High School Students. First 20 items are taken from standardized tool for validation. An item analysis technique was used for this study. The sample consists of 50 High School Students. They are randomly selected from Kancheepuram District. The Difficulty level and Discrimination index values were used to validate the tool and 14 items were retained. Again researcher constructed 12 items for validation. Same techniques and samples were used and this time 6 items were retained. Thus, totally 20 items were retained for the final study.
PEACEBUILDING PRACTICES OF JAPAN: LESSONS FROM SRI LANKA
Authors: Wijegoonawardana Nirmali
Published: October 2020

Peacebuilding involves a process that includes different roles and functions. It also ranges from a series of activities such as ceasefire and refugee resettlement to the development of revised economic reconstruction and a new government. International communities have significantly increased aid for prevention of conflict, rapid humanitarian aid and reconstruction in post-conflict zones. In the wide spectrum of peacebuilding, the Government of Japan which had been certain to dedicate to traditional development issues widened the activities beyond the development after 2002. That was the time to respond to the Sri Lanka conflict with the Japan’s policy on Consolidation of Peace. The aim of this paper is to examine the peacebuilding efforts of the Japanese government since 2002 in post-conflict Sri Lanka. The study adopts a descriptive nature through the use of a qualitative method. This paper will also scale the effectiveness of the Japanese peacebuilding efforts in Sri Lanka.
MORPHOLOGICAL EVOLUTION OF THE BOTTOM OF THE POTOU LAGOON OVER THE LAST TEN YEARS (COASTAL ZONE OF COTE D'IVOIRE)
Authors: Eric DIANGONE , Colette AKOBE Apie , Mireille Amani Etché , Sylvain MONDE , Aoua COULIBALY
Published: October 2020

This study with a morphology and hydrosedimentology character was done to carry out a with an understanding the evolution of the channels and sedimentation in Potou lagoon in Ivory Coast starting from the realization of the bathymetric map. The bathymetry of this lagoon avered that the depths are lower than 2.11 m out of 22 km2, and presente three types of channels. In fact the channels in "U" represent a balance between the agents of accumulation and erosion. Channels resulting from processes of erosion which are in "V" and channels intermediate indicating an evolution of the type "V" in "U". In particular during these fourteen last years the Potou lagoon has sudden great phenomenon of deposit is a volume of +66791000.18 m³of sediments deposed on a surface which is thus estimated at 65.2 % of chenal surface. These deposits are certainly causes of full high funds in this lagoon. The mean velocity of sedimentation on Potou lagoon is thus estimated at 26.5 cm/year. As for the erosion, it could be estimated at-8487601 m³ a volume of on a surface wich is thus estimated at 34 % of chenal surface. The sedimentary budget would be thus estimated at+58303398.68449 m³ on a surface of 12.45 m2. A surface which is thus estimated at 0.8 %hasn’t sudden phenomenon of deposit or erosion. The bathymetric chart and the sedimentary budget of Potou lagoon are tools necessary for use of the stretch of water by the users. Thus, the zones at the risks determined on the bathymetric chart, such as the high bottom and the points of swirl generated by the depressions, will be easily avoided.
THE SECOND-GENERATION PLATELET CONCENTRATES IN THE TREATMENT OF CHRONIC OSTEOMYELITIS: ONE MODERN REGENERATIVE SURGERY
Authors: Crisci Alessandro , Raffaele D’Adamo , Crisci Michela
Published: October 2020

Background: Hypothesis is that the use of fibrin rich in leukocytes and platelets advanced (A-PRF) in ulcer osteomyelitis on diabetic foot, allows recovery from this serious disease. In this study, the goal was to standardize the use of PRF in patients with osteomyelitis, to use this second-generation platelet concentrate, as a facilitator of healing.

Methods: Authors produced and used peripheral blood A-PRF (1300 g × 8 min) membranes in 7 patients (all diabetic) with osteomyelitis and skin lesions for at least 6 months. Membranes, together with the supernatant liquid derived from compression, were inserted into the skin lesion down to the bone after surgical debridement. Evolution of the lesions over time was analyzed.

Results: All seven patients had a positive Probe-to-Bone test, MRI detected cortico-periosteal thickening and/or foci of cortico-cancellous osteolysis adjacent to the ulcer. Gram-positive bacteria were found in our patients in 52% of cases. Cocci Gram +, such as S. Aureus (15.6%), S. -haemolytic (12.1%), S. Viridans (7.1%), and Bacilli Gram- such as Pseudomonas (10.6%), Proteus (7.8%), Enterobacter (5.7%) are present. Candida Albicans is present in 2.8%. Blood count showed no major changes.

To date, skin lesions have healed in 6 of the seven patients treated (one patient for more than five years) with no signs of infection or recurrence.

Conclusions: Results obtained on our patients suggest that PRF membranes may be a therapeutic option in this difficult to treat pathology.
INVESTIGATIVE COMPETENCES IN HEALTH PROFESSIONALS
Authors: Navarro Marlene Hernández , Panunzio Amelia Patricia , Dáher Nader Jorge Elías , Moya Mario Ángel Royero , Hernández Est. Claudia Patricia Fernández
Published: October 2020

Investigative competencies are necessary to carry out an optimal and efficient research process. Descriptive research is presented whose general objective is to design a proposal of investigative competencies in the areas of the study plan of the medical career. The specific objectives are: to characterize the teachers and students of the medical career, identify the research activities in progress, describe the scientific and technical competences for the performance of the research and design a proposal of investigative competences in the three areas of the plan of study of the medical career of an Ecuadorian university.
Atık Kayıt Ortamlarının Veri Güvenliği Yaklaşımı ile Değerlendirilmesi
Authors: ÖZTÜRK Tuba
Published: October 2020

Bu çalışmada yapılarında kayıt ortamı bulunduran cihazların, atık konumuna geçtikten sonra veri güvenliği açısından değerlendirilmesi amaçlanmıştır. İçinde bulunduğumuz çağın özelliklerine bağlı olarak günümüz insanları, büyük ölçüde teknoloji odaklı yaşamaktadır. Bilgisayar, akıllı telefon, tablet, internet vs. artık yaşamın ayrılmaz parçaları olarak, hemen hemen tüm faaliyetlerin merkezinde bulunmaktadır. Günümüz teknolojisinin en önemli özelliği çok kısa sürede kendini yenilemesi, geliştirmesi, değiştirmesidir. Bu durum teknoloji temelli cihazların kullanım ömürlerinin, her geçen gün daha da kısalmasına neden olmaktadır. Gerek cihazların depolama kapasiteleri, gerekse aktivitelerin çoğunlukla bu cihazlar üzerinden gerçekleştirilmesi, söz konusu cihazlarda önemli miktarda bilginin toplanması ve depolanması anlamına gelmektedir. Cihazların kullanım süreleri dikkate alındığında bu durum, veri güvenliği açısından ciddi endişelere yol açmaktadır. Verilerin kalıcı şekilde silinmesinin, teknik bilgi gerektiren oldukça karmaşık bir süreç olması bu endişelerin başlıca nedenidir. Çoğu durumda kullanıcıların teknik bilgilerini aşan silme işlemi, veri yönetiminin en az verilerin saklanması kadar önemli bir diğer alanıdır. Bu yaklaşım her durum ve her ortamdaki veri için geçerlidir. Özellikle atık kayıt ortamlarındaki verilerin bu kapsamda değerlendirilmesi gizlilik ve güvenlik açısından son derece önemlidir.
Correlations of Nitrogen, Phosphorus, Potassium, Pigments and Total Flavonoids of Moringa oleifera Lam. Leaves in the Vegetative and Generative Phases
Authors: Rasmani Rasmani , Aziz Sandra Arifin , Suketi Ketty
Published: October 2020

Moringa oleifera is universally known as the miracle plant or the tree of life. Moringa leaf extract contains phenolic acids and flavonoids, especially flavonols (quercetin, kaempferol, isorhamnetin glycosides) and flavones (apigenin). This study aimed to elucidate any correlations between nutrient, pigment, and flavonoid concentrations for different leaf positions and different growth phases. The results showed that pigment and total flavonoid concentrations increased from the 1st leaf to the 5th leaf, while nutrient concentration decreased. Pigment concentration, total flavonoid, and nutrient concentration were higher in the vegetative phase than the generative phase. The concentration of nutrients in the generative plants displayed a significant positive correlation with chlorophyll concentration. The 1st to 5th leaf of the vegetative plants can be used as indicator leaves for tissue analysis of the moringa plant.
Expression of miR-21 in Colorectal Cancer and Its Relationship with Clinicopathological Characteristics of Colorectal Cancer
Authors: Lei Jia
Published: October 2020

Objective: To investigate the expression of miR-21 in colorectal cancer cells, and to analyze the relationship between the level of miR-21 and the clinicopathological characteristics of colorectal cancer patients. Methods: 210 patients with colorectal cancer treated in our hospital from January 2016 to June 2019 were selected. Cancer tissue specimens (study group) and adjacent normal tissue specimens (control group) were surgically collected, and the quantitative quantitative PCR was used to detect and compare the miR-21 expression of the two groups. Results: The expression of miR-21 in the study group was higher than that in the control group, and the difference was statistically significant (P <0.05). There were significant differences among patients with early and intermediate TNM, patients with low differentiation and patients with moderate to high differentiation, patients with lymph node metastasis and patients without lymph node metastasis, patients with high infiltration and patients with low infiltration, patients with high CEA levels, and patients with low CEA, and the difference was statistically significant (P <0.05). Conclusion: In colorectal cancer, miR-21 is highly expressed, which is closely related to stage and differentiation, and can be used to reflect the patient’s condition.
Advances in Single Nucleotide Polymorphisms of Vitamin D Metabolic Pathway Genes and Respiratory Diseases
Authors: Li Zhilu , Li Honghai , Li Saijia , Du Yingjing , Xu Bingxin , Wang Yuxuan , Zhang Yunxia
Published: October 2020

Vitamin D is a fat-soluble vitamin. It is an essential vitamin for human body. It has a classical effect on regulating calcium and phosphorus metabolism. Participate in cellular and humoral immune processes by regulating the growth, differentiation and metabolism of immune cells. A large number of studies in recent years have shown that vitamin D deficiency increases the incidence of respiratory diseases. Respiratory diseases mainly include bronchial asthma, chronic obstructive pulmonary disease, tuberculosis, acute upper respiratory tract infection and pneumonia. Vitamin D metabolic pathway genes play a very important regulatory role in the transformation of vitamin D into active vitamin D, including CYP2R1,,CYP27B1, CYP24A1, VDBP, VDR five genes. Genetic polymorphism of genes is the molecular basis of individual differences and disease development. Therefore, this paper summarizes the research on single nucleotide polymorphism of vitamin D metabolic pathway gene and respiratory diseases. In order to provide a new idea for future treatment.
Carried hepatitis B among Libyan patients who attended the Al Zawia street hospital
Authors: Khaled Ali Alawaini  , Numidya Ali Omar  , Hunida Saed Alhush  , Eman Yakhlef kamkoum  , Esra Ahmed Alazabi
Published: October 2020

Hepatitis B (HBV) is a significant liver disease that affects roughly 400 million individuals globally with chronic infection, leading to liver cirrhosis or carcinoma. The virus can spread through blood transfusion, sexual contact, or the use of contaminated needles. HBV is more prevalent in developing countries than developed ones. However, it is estimated that 5% to 10% of the global population carry the virus, whereas, in North America and western Europe, only 1% of the people have a chronic infection. Our objective is to determine the prevalence of HBV and identify the disease’s risk factors. We conducted a statistical study, and data were collected through the Al Zzawia street hospital from November 1, 2010, to January 1, 2011. Our results concluded that the prevalence of HbsAg was higher in 2005 than in 2010. HBV was also found to be more prevalent in males than in females. As a result, more attention and guidance, especially for young people, could reduce the spread drastically.
Evaluation of thyroid disorders in cotton growers exposed to pesticides in Satiri department
Authors: Bazoma Bayili  , Ollo Da  , Jean Fidèle Bationo  , Véronique Panne Coulibaly  , Sylvain Ilboudo  , Richard Ouedraogo  , Jean Bosco Ouedraogo  , Georges Anicet Ouedraogo
Published: October 2020

Cotton farmers are exposed to a variety of pesticide formulations, some of which contain active endocrine disrupting substances. The objective of this study was to investigate the link between pesticide exposure and thyroid disorders in cotton growers. This was a longitudinal prospective study among cotton producers during and after the 2018/2019 cotton season in the Satiri department. Surveys have been conducted on a cohort of 50 producers to collect socio-demographic and professional information on the producers and the pesticides used. A medical examination of the producers followed by blood samples were carried out during and after the cotton season. The thyroid stimulating hormone (TSH), Free tetra- iodo-thyronine (FT4) and Free tri-iodo-thyronine (FT3) biomarkers were measured on the Cobas®6000 automaton. During the cotton campaign, an overall frequency of 12.00% of dysthyroidism, of which 8.00% of hypothyroidism and 4.00% of hyperthyroidism were recorded. After the campaign, 14.00% dysthyroidism was observed, including 8.00% of hypothyroidism and 6.00% of hyperthyroidism. Also, a significant decrease in TSH concentrations; a significant increase in FT4 and a non-significant decrease in FT3 were observed. This study does not establish a specific link between exposure to pesticides and thyroid disorders due to the complexity and cocktail effect of pesticides. Rational use of these products is essential to avoid health effects linked to endocrine disruption.
Performance assessment of Bhendi hybrid Co 4 cultivation over local check variety under Front Line Demonstration
Authors: V. Sivakumar  , S. Praneetha  , R. Balakumbahan  , B. Meena  , G. Thiyagarajan  , M. Alagar
Published: October 2020

A field investigation on productivity augmentation of bhendi [Abelmoschus esculentus L. Moench] was carried out at Melanagai village, Mannargudi block of Thrivarurur district. The study was conducted by ICAR-Krishi Vigyan Kendra, Needamangalam [Tamil Nadu], during 2016-17 to assess the bhendi/okra hybrid Co 4 performance along with local check variety.The per cent yield improvement, technology gap, extension gap, technology index were calculated based on the observation recorded on growth, yield and economical attributes of both demonstration and local adopted check variety. The recorded data showed that the average yield of demonstration plots was 20.35 tha–1whereas the local check recorded an average yield of 12.80 tha–1 and there is an amplified average yield by 37.21 per cent. The gross returns and benefit cost ratios from the demonstration plot were higher [Rs. 121020/ha and 2.80 respectively] as compared to farmer’s practices [Rs. 76800/ha and 1.90]. The demonstrated improved variety i.e. okra hybrid Co 4 recorded superior growth, yield and economical parameters of the local adopted check variety. The enhancement in growth, yield and economic parameters under okra hybrid Co4 than the farmers’ practice [local check] signifying the technical and economic viability of improved variety / hybrid over farmers practices.
Toxicity of two groups of pesticides against the mosquito Aedes aegypti
Authors: Mohammed Rashed Al Zahrani  , Fatehia Nasser Gharsan  , Khalid Mohammed Al-Ghamdi  , Jazem Abdullah Mahyoub  , Tariq Saeed Alghamdi
Published: October 2020

The mosquito Aedes aegypti (Linnaeus) (Diptera: Culicidae) is a vector for several pathogens that affect human health worldwide. Therefore, mosquito control is the best approach to prevent disease outbreaks. In this milieu, it is preferable to evaluate the effectiveness of chemical pesticides at regular intervals to identify the most effective ones and use them during the outbreaks of diseases and spread of pests. Here, we aimed to study the toxicity of six pesticides, which are classified under two groups, namely pyrethroids and organophosphates, against A. aegypti mosquitoes to improve disease control in Saudi Arabia. Hortak was the most effective in larval mosquito control (LC50 = 0.0031 ppm), followed by Aquapal Super 20 EW (LC50 = 0.0389 ppm), whereas Solfac was the least effective (LC50 = 0.1119 ppm). In addition, the sensitivity of the tested larvae to Safrotin and Keen 600 EC was 8.1 and 58.9 times higher than that to Resfin-5, which was the least effective, respectively. Hortak and Safrotin exhibited the highest toxicity against the larvae of A. aegypti. Our findings confirm that the tested pesticides can be used in mosquito-control programs during epidemic outbreaks and emergency.
UV spectrophotometric method for estimation of zileuton in pharmaceutical formulation
Authors: Romana Mahivish  , Manjunath SY  , Hemant Kumar
Published: October 2020

A simple, rapid, sensitive and accurate UV-spectrophotometric method has been developed for the estimation of zileuton in pharmaceutical formulation. The method was developed by using 0.1 N Sodium hydroxide as a solvent and absorbance was measured at 230 nm. The drug exhibited the linearity in the concentration range of 1-6 μg/ml with correlation coefficient of 0.9993. The % recovery of the drug was found to be 98.62 % - 100.5 %. The method was validated as per ICH guidelines. The proposed methods are economical and sensitive for the estimation of zileuton in bulk and tablet dosage form.
PENINGKATAN HASIL BELAJAR PENDIDIKAN AGAMA KRISTEN MELALUI MODEL PEMBELAJARAN KOOPERATIF TIPE TWO STAY TWO STRAY BAGI SISWA KELAS 5 SD NEGERI TOISAPU
Authors: Johannes Nathalia Yohanna
Published: October 2020

Pembelajaran Pendidikan Agama Kristen pada hakekatnya berpangkal atau berpokok kepada Allah sendiri karena Allah-lah yang menjadi Pendidik Agung bagi umat-Nya. Oleh sebab itu pembelajaran Pendidikan Agama Kristen perlu dirancang dengan baik, dengan metode yang tepat maupun cara pembelajaran yang kreatif dan efisien. Rancangan pembelajaran tersebut harus mampu menjadikan anak memiliki landasan kepercayaan yang kokoh kepada Tuhan Yesus.Sekolah Dasar adalah pondasi awal bagi siswa untuk bisa meneladani hal-hal yang baik.Pertumbuhan iman anak yang signifikan kepada Tuhan Yesus patut dibangun pada masa ini.Oleh sebab itu Pendidikan Agama Kristen sebagai sebuah mata pelajaran yang menekankan pendidikan karakter dan budi pekerti membutuhkan sebuah model pembelajaran yang menarik bagi siswa. Model yang mampu memotivasi siswa untuk berbicara, mengeluarkan pendapat serta memiliki hubungan kerja sama antara satu siswa dengan siswa yang lain. Kemampuan berbicara dan mengeluarkan pendapat tentunya sangat baik untuk mendorong siswa dalam memiliki kecakapan untuk bersaksi kepada orang lain tentang perbuatan-perbuatan Allah dalam dirinya. Dengan rancangan yang tepat, hasil belajar dalam Pendidikan Agama Kristen tentu akan meningkat. Penelitian ini dilakukan dengan menggunakan tipe penelitian tindakan kelas yang bertempat di SD Negeri Toisapu Ambon.Penelitian dilakukan untuk meningkatkan hasil belajar siswa melalui model pembelajaran TSTS.Hasil penelitian menunjukkan bahwa model pembelajaran TSTS berhasil meningkatkan hasil belajar siswa dalam pembelajaran Pendidikan Agama Kristen.Pendidikan Agama Kristen
DAMPAK BULLYING BAGI KALANGAN SISWA SEKOLAH DASAR
Authors: Patras Yuyun Elisabeth , Sidiq Fajar
Published: October 2020

The  research  is  a  study  case,  its  location  in  the Ciparigi State Elementary School Bogor, West Java. The focus of this research is the impact of bullying for the social interaction of elementary school students. Data collection technique form is through observation, interviews and documentation. Validity of data examination that used are credibility, transferability, dependability and confirmability. Analysis of data that used   is   qualitative   descriptive.   The   results   were showed that forms of bullying occurs in Ciparigi Elementary School including physical bullying and verbal bullying. As a result, subjects had a impact on the social interaction that makes the subject difficult to interact with the environment because it is always on a bully by the other students. Difficulty interacting is a major problem faced by the subject because the subject becomes not dare to start interacting not only to his friend, but the teachers as well as parents. Conclusions from this research is the  impact of bullying on the victim's social interactions at school or outside the school.
THE INFLUENCE OF DEBATE TECHNIQUE, AND STUDENTS' CRITICAL THINKING TOWARDS THEIR SPEAKING ABILITY
Authors: Ali Djena , Souisa Threesje Roza
Published: October 2020

This study is aimed at a) describing the students   speaking   ability   and   their   critical thinking level, b) finding out the significant influence   of   speaking   ability   between   the students who are taught with debate technique and those who are taught with group discussion technique, c) finding out the significant differences in speaking ability between the students  who  have  high  critical  thinking  and those who have low critical thinking, and d) finding out the significant interaction in speaking ability between teaching techniques and critical thinking   skill.The   quasi-experiment   method under  a   quantitative  approach  was   used  to conduct the study. The design of the study is 2x2 with pre-post-test control group design. In analyzing the data, descriptive and inferential statistics were used. The results show that the students‟ speaking ability is in the high level, whereas in critical thinking skill there were 48 students who can be categorized as having high critical thinking and 32 students who have low critical thinking. The students who are taught by using debate technique have better achievement in  speaking ability than  those who  are  taught with  discussion technique. There is  a  positive and  significant influence on  students speaking ability between the students who are taught by debate technique with those who are taught with discussion technique. There is a positive and significant difference in speaking ability between the students who have high critical thinking and those who have low critical thinking. There is a positive and significant interaction of speaking ability between the teaching techniques and critical thinking.
YÜKSEKÖĞRETİMDE KAYITLI ÖĞRENCİLERİN EKONOMİK PROFİLİ ÜZERİNE BİR ARAŞTIRMA
Authors: DİNERİ Eda , GÖLPEK Filiz
Published: October 2020

Bu çalışmada 2018-2019 öğretim yılında Kilis 7 Aralık Üniversitesi’nde kayıtlı öğrencilerin ailelerin ekonomik profillerine göre yükseköğretime giriş sınavına hazırlık sırasında ve yükseköğretim süresince gelirlerinden ne kadar pay ayırdıkları incelenmiştir. Araştırma sonucunda, öğrencilerin % 90’ının yükseköğretime hazırlık maliyetlerinin aileleri tarafından karşılandığı belirlenmiştir. Yükseköğretime hazırlık aşamasında dershaneye yapılan harcamalar ile ilgili soruya öğrencilerin sadece %15’inin cevap verdiği ve ortalama 2.000-3.000 arasında harcandığı ve ailelerinin büyük çoğunluğunun asgari ücretin altında bir gelire sahip olduğu tespit edilmiştir. Yükseköğretim süresince de öğrencilerin %66’sının aylık özel harcamaları aileleri tarafından, %26,3’ü burs/kredi olarak karşılanmıştır.
Analytic Hierarchy Process (AHP) dan Fuzzy TOPSIS pada Pemilihan Himpunan Pairing Terpilih dari Jadwal Penerbangan
Authors: Rahmalia Dinita , Rohmah Awawin Mustana , Azizah Nuril Lutvi
Published: October 2020

In the flight industry, there are two highest costs such as fuel cost and crew cost. The crew cost is affected by pairings selected from flight schedule. This research will explain about selecting the set of selected pairings using Analytic Hierarchy Process (AHP) and Fuzzy Technique for Order Performance by Similarity to Ideal Solution (Fuzzy TOPSIS). Before using either Fuzzy AHP or Fuzzy TOPSIS, it will be formed collection of the set of selected pairings using greedy algorithm. After collection of the set of selected pairings is formed, then we determine goal and criteria. The goal is selecting the set of selected pairings from some alternatives. For each the set of selected pairings, there are some criterions such as the number of deadhead, the number of pairing A2, the number of pairing A3, the number of pairing A4, the number of pairing A5, and the number of pairing A6. Based on simulation results, both AHP and Fuzzy TOPSIS can select and give the rank of priority in entire the set of selected pairings. Â Pada industri maskapai penerbangan, terdapat dua biaya yang sangat besar yaitu biaya bahan bakar dan biaya kru. Biaya kru dipengaruhi oleh pairing yang terpilih dari jadwal penerbangan. Pada penelitian ini akan dilakukan pemilihan himpunan pairing terpilih menggunakan metode Analytic Hierarchy Process (AHP) dan Fuzzy Technique for Order Performance by Similarity to Ideal Solution (Fuzzy TOPSIS). Sebelum menggunakan AHP atau Fuzzy TOPSIS, akan dibentuk kumpulan dari himpunan pairing terpilih menggunakan greedy algorithm. Setelah kumpulan himpunan pairing terpilih terbentuk, maka dibentuk goal dan kriteria. Goal adalah memilih himpunan pairing terpilih dari beberapa alternative. Pada setiap himpunan pairing yang terpilih, terdapat beberapa kriteria seperti jumlah deadhead, jumlah pairing A2, jumlah pairing A3, jumlah pairing A4, jumlah pairing A5, dan jumlah pairing A6. Berdasarkan hasil perhitungan, metode AHP dan Fuzzy TOPSIS dapat memilih dan memberi peringkat prioritas pada pemilihan himpunan pairing terpilih.
Differentiation Among Rodentibacter Species Based on 16S–23S rRNA Internal Transcribed Spacer Analysis
Authors: Benga Laurentiu , Benten Peter M , Engelhardt Eva , Köhrer Karl , Hueber Barbara , Nicklas Werner , Christensen Henrik , Sager Martin
Published: October 2020

The internal transcribed spacer (ITS) regions of Rodentibacter pneumotropicus, R. heylii, R. rarus, R. ratti, and R. heidelbergensis and of a Rodentibacter- related β-hemolytic Pasteurellaceae taxon isolated from laboratory rodents
were studied for their feasibility to discriminate among these species. The 6 species analyzed showed species-specific ITS patterns that were shared by the type strains and clinical isolates and that allowed their identification. Nevertheless, differentiating between the ITS band patterns
of R. pneumotropicus and R. ratti is visually challenging. In all species tested, sequence analysis of the ITS fragments revealed a larger ITSile+ala, which contained the genes for tRNAIle(GAU) and tRNA Ala(UGC), and a smaller
ITSglu with the tRNAGlu(UUC) gene. The ITS sequences varied among the 6 species evaluated, displaying identity levels ranging from 62% to 86% for ITSile+ala and 68% to 90% for ITSglu. Overall, ITS amplification proved
to be a reliable method to differentiate among these important Pasteurellaceae species of laboratory rodents. Moreover, the ITS sequence variations recorded here might facilitate the design of probes for specific identification of these species. The ability to diagnose these organisms
to the species level could increase our understanding of their clinical significance.