bluuebunny/crossref_metadata_2025 huggingface dataset:
Trivselsfremmende og adgangsskabende po-tentialer af hybride koncertformater: En komparativ analyse af Musikalske Besøgsvenner og SOLO
Authors: Schneidermann Nanna , Bakkær Munk Andersen Amalie Bakkær Munk Andersen , Kronborg Hansen Tanja
Published: May 2024

ROSA arrangerede mellem 2021 og 2023 i alt 400 koncerter som en del af projekterne Musikalske Besøgsvenner og SOLO. Musikalske Besøgsvenner forbinder kunstnere med brugere af besøgsvennetjenester for koncerter i hjemmet, mens SOLO giver sårbare unge mulighed for intime koncerter i velkendte omgivelser. Et centralt element i begge projekter er et videnssamarbejde med Afdeling for Antropologi ved Aarhus Universitet med formål at udforske forholdet mellem intime kunstneriske møder, kulturel deltagelse og trivsel blandt sårbare grupper. Denne rapport opsamler 3 ½ års forskning i begge projekter og analyserer sammenfald og forskelle i projekterne i forhold til sundheds- og trivselsfremmende potentialersamt adgangsskabende faktorer for sårbare ældre og yngre borgere.
Van koşullarında damla sulama yöntemi ile sulanan elma ağaçları için teorik bitki su tüketimine dayalı sulama programının oluşturulması
Authors: Usta Selçuk
Published: May 2024

Bu çalışmada, damla sulama yöntemi ile sulanacağı öngörülen elma ağaçlarının teorik su tüketimi ve sulama suyu ihtiyaçlarının belirlenerek, sulama programlarının oluşturulması amaçlanmıştır. Çalışma, uzun yıllar ortalama günlük iklim verileri (2012 – 2020) ile 2021 ve 2022 yılı güncel günlük iklim verileri kullanılarak yürütülmüştür. Öncelikle Penman & Monteith (PM) eşitliği FAO-56 modifikasyonu kullanılarak elma ağaçlarının büyüme mevsimi (20 Nisan – 30 Ekim) boyunca günlük ortalama referans bitki su tüketimi (ETo) değerleri tahmin edilmiştir. Daha sonra elma ağaçlarının başlangıç (0.52), orta (1.00) ve son dönem (0.74) bitki katsayıları (kc) ile 190 gün süreli büyüme mevsiminin başlangıç, gelişme, orta ve son dönem uzunlukları dikkate alınarak AutoCAD programı aracılığıyla günlük kc katsayısı grafiği çizilmiştir. Günlük ortalama ETo değerleri bu grafikten okunan kc katsayıları ile düzeltilerek, günlük ortalama bitki su tüketimi (ETc) değerleri elde edilmiştir. Bir boyutlu su dengesi eşitliği kullanılarak, etkili kök derinliği bölgesindeki toprak nemi düzeyinde meydana gelen günlük değişimler belirlenmiştir. Bu bölgedeki kullanılabilir suyun %40’ı elma ağaçları tarafından tüketildiğinde sulama yapılacağı ve mevcut toprak nemini tarla kapasitesine yükseltecek miktardaki sulama suyunun elma ağaçlarına verileceği öngörülmüştür. Elma ağaçlarının ortalama 15 gün süreli her bir sulama aralığındaki ortalama su tüketimi 72.91 mm olarak belirlenmiştir. Her bir sulamada uygulanması gereken ortalama sulama suyu miktarı ise 65.50 mm olarak elde edilmiştir. Son sulamaya kadar ortalama 679.28 mm düzeyine yükselen mevsimlik toplam su tüketiminin sulamada damla sulama yöntemi kullanılması durumunda %14.70 oranında azalarak 579.43 mm düzeyine gerilediği görülmüştür. Bu bitki su tüketimine karşılık olarak uygulanması gereken mevsimlik toplam sulama suyu miktarı ise 523.70 mm olarak belirlenmiştir. Birincisi Haziran ayı ortasında ve sonuncusu ise Eylül ayı sonunda olmak üzere ortalama 8 adet sulama yapılması gerektiği sonucuna ulaşılmıştır. Teorik bitki su tüketimine dayalı olarak elde edilen bu sonuçların, Van ili koşullarında elma ağaçları için yapılacak damla sulama uygulamalarında aydınlatıcı olacağı düşünülmektedir.
Presença do luteranismo no Brasil
Authors: Westphal Euler Renato
Published: May 2024

A presença do luteranismo está intrinsecamente ligada à imigração alemã no Brasil, a partir de 1824. Há iniciativas em acionar memórias do processo da existência de 200 anos do luteranismo no Brasil, em especial, pela Igreja Evangélica de Confissão Luterana no Brasil (IECLB). O objetivo deste artigo é analisar relações entre ecumenismo e luteranismo, na perspectiva da doutrina trinitária interpretada por Martinho Lutero. O luteranismo é um fenômeno cultural, teológico, religioso e filosófico de leque amplo e complexo. Na história do luteranismo encontramos a vertente ortodoxa da interpretação dos símbolos ecumênicos, bem como a corrente racionalista, que propôs a rejeição ou superação da doutrina trinitária. Ambas formaram o luteranismo no Brasil, que em seus inícios, viveu na diáspora e foi vítima da segregação religiosa e política. Há muitas décadas, o luteranismo está construindo pontes ecumênicas. Nesse amplo tema sobre o ecumenismo, este artigo enfatiza, breve e provisoriamente, a doutrina trinitária, que é o eixo norteador de todas as igrejas cristãs históricas. Assim, este trabalho propõe reflexões para que a teologia trinitária, interpretada por Lutero, mobilize Igrejas cristãs ao entendimento a partir de suas bases confessionais comuns. A investigação bibliográfica é a metodologia utilizada com base na literatura especializada e em dados on-line.
UMA VIDA RESPONSÁVEL
Authors: Ferreira Lucas dos Santos , De Souza Edilson Soares
Published: May 2024

O presente artigo apresenta uma análise da obra Ética, do teólogo alemão Dietrich Bonhoeffer, destacando-se um estudo que o autor faz sobre a vida responsável, e a estrutura dela parametrizada por ele. Propõe-se uma breve introdução ao contexto histórico do autor, um histórico sobre o conceito não inédito de “ética da responsabilidade”, que pode ter sido usado como base de Bonhoeffer para o desenvolvimento da estrutura da vida responsável. Após isso, é feita uma breve exposição dos conceitos que compõem essa estrutura, os quais são: representatividade, conformidade com a realidade e liberdade. Por último, é feita uma aplicação desses conceitos à vida cristã contemporânea. Foram usados como referência para a análise da obra e do conceito os artigos de CÂMARA (2003) e RODRIGUES (2011). Para a análise do contexto histórico, recorreu-se a GIBELLINI (2002) e GUNDRY (1983), enquanto que para a aplicabilidade contemporânea, analisou-se DENVER (2016), ORTIZ (1983) e RABEY (2004).
Application of multimodality perception scene construction based on Internet of Things (IoT) technology in art teaching
Authors: Wang Haiwen , Wang Yahui , Jin Juan
Published: May 2024

Numerous impediments beset contemporary art education, notably the unidimensional delivery of content and the absence of real-time interaction during instructional sessions. This study endeavors to surmount these challenges by devising a multimodal perception system entrenched in Internet of Things (IoT) technology. This system captures students’ visual imagery, vocalizations, spatial orientation, movements, ambient luminosity, and contextual data by harnessing an array of interaction modalities encompassing visual, auditory, tactile, and olfactory sensors. The synthesis of this manifold information about learning scenarios entails strategically placing sensors within physical environments to facilitate intuitive and seamless interactions. Utilizing digital art flower cultivation as a quintessential illustration, this investigation formulates tasks imbued with multisensory channel interactions, pushing the boundaries of technological advancement. It pioneers advancements in critical domains such as visual feature extraction by utilizing DenseNet networks and voice feature extraction leveraging SoundNet convolutional neural networks. This innovative paradigm establishes a novel art pedagogical framework, accentuating the importance of visual stimuli while enlisting other senses as complementary contributors. Subsequent evaluation of the usability of the multimodal perceptual interaction system reveals a remarkable task recognition accuracy of 96.15% through the amalgamation of Mel-frequency cepstral coefficients (MFCC) speech features with a long-short-term memory (LSTM) classifier model, accompanied by an average response time of merely 6.453 seconds—significantly outperforming comparable models. The system notably enhances experiential fidelity, realism, interactivity, and content depth, ameliorating the limitations inherent in solitary sensory interactions. This augmentation markedly elevates the caliber of art pedagogy and augments learning efficacy, thereby effectuating an optimization of art education.
Nova economia institucional: um estudo sobre possíveis contribuições das instituições no desenvolvimento económico
Authors: Chadreque Juvenal Laurinda da Silva
Published: May 2024

Realizou-se uma pesquisa bibliográfica e documental, adoptando uma abordagem exploratória, que é uma estratégia particularmente adequada ao estudo da Nova Economia Institucional. Este campo, emergente e dinâmico, foca na interação entre as instituições. Sejam formais, como leis e políticas, ou informais, como normas culturais e práticas sociais, e o desenvolvimento económico. Dada a complexidade e a vastidão do conhecimento neste domínio, uma metodologia exploratória permite aos pesquisadores uma compreensão mais profunda e abrangente das variáveis em jogo, assim como das inter-relações entre as instituições e a economia. Para averiguar estas informações adoptou-se como referência aos estudos feitos por Douglass North, especialmente sob o prisma em estudo. Mostra que o tema, em debate com outras correntes institucionalistas, revela limitações e contradições teóricas importantes. Os custos de transação ocorrem, em grande medida, devido à capacidade racional limitada dos seres humanos e as incertezas próprias do meio, gerando com isto problemas na especificação dos direitos de propriedades. O objectivo central desta pesquisa foca em demonstrar como as instituições podem não apenas facilitar, mas também acelerar os processos de desenvolvimento económico, através da implementação de políticas eficazes, criação de ambientes estáveis para o investimento, e promoção da justiça social e económica. Conclui-se que o estudo é um arcabouço teórico limitado para a compreensão das estruturas de governança, e por sua vez, as instituições são essenciais para o crescimento e desenvolvimento económico de um país.
Mundo virtual e saúde mental: influência das mídias sociais na autoimagem dos adolescentes
Authors: Comin Breno Cristiano , Soares Nandra Martins , Mombelli Mônica Augusta
Published: May 2024

Com o avanço da tecnologia e o crescente acesso às redes sociais, os adolescentes estão cada vez mais imersos no ambiente virtual. No entanto, essa exposição constante pode gerar consequências significativas para a saúde mental dos jovens. Nesse sentido, o objetivo desta pesquisa foi compreender o impacto das redes sociais no desenvolvimento especificadamente da autoimagem dos adolescentes. Trata-se de uma pesquisa bibliográfica integrativa da literatura, na qual realizou-se uma busca nas bases de dados Scielo, Lilacs e Bireme. Foram selecionados artigos científicos dos últimos sete anos, publicados nos idiomas português, inglês e espanhol. Os resultados demonstraram que as mídias sociais podem influenciar na autoimagem dos adolescentes de maneira positiva quando usado com moderação, mas também de forma negativa. A saúde mental pode ser afetada pela exposição aos padrões de beleza e de vida inalcançáveis; pela incidência de comentários negativos, além da comparação constante nas redes sociais que também confrangem o desenvolvimento da autoestima e da autoimagem. Portanto, é essencial que sejam implementadas medidas educativas e preventivas para promover o uso saudável das redes sociais entre os jovens, capacitando-os a navegar criticamente no ambiente digital e a proteger sua saúde mental. Além disso, políticas de regulamentação e proteção online são necessárias para mitigar os riscos associados ao uso excessivo e prejudicial das redes sociais na formação geral da personalidade deste público.
A Christological Reflection on Yom Kippur from an Akan Christian Perspective
Authors: Boaheng Isaac
Published: May 2024

The Day of Atonement (Yom Kippur) is arguably the holiest and most important day in ancient Israel’s religious calendar. In the Christian religion, the Yom Kippur ritual is interpreted to foreshadow the ultimate sacrifice made by Christ for the atonement of the sin of humanity. Therefore, a theological study of this Old Testament atoning ritual has the potential to shed light on the salvific ministry of Christ. Using a literary research approach, this article explores how atoning practices associated with Yom Kippur might enhance the Christian understanding of Jesus’ atoning sacrifice. I argue that by fulfilling what the Old Testament sacrificial system prefigured, the cross renders any atoning sacrifice obsolete. Therefore, believers ought to refrain from any form of traditional religious sacrifices because such sacrifices have no salvific value. The paper contributes to the ongoing scholarly discourse on Christian soteriology, particularly the doctrine of atonement. Keywords: Akan, Atonement, Christ, Leviticus, Yom Kippur
Leadership and Spiritual Resources in the Anthropocene: Some Practical Theological Reflections
Authors: Nell Ian
Published: May 2024

Faith communities are found all over the world as spaces where people find a spiritual home and where spiritual formation takes place. For this contribution, the research question is: In what ways can the leadership in faith communities contribute towards spiritual resources for their members in the time of the Anthropocene? Faith communities are spaces where three resources (a shared narrative about climate change, shared values and shared symbols and practices) interact and where each of these can also make a unique contribution to raising awareness of ownership and space in the time of the Anthropocene. If the Anthropocene is considered as the period in which human activities have the dominant influence on the climate and the environment, these three resources offer important contributions for a greater awareness of humans’ influence on the climate and the environment. The congregational leader as spiritual guide in the modes of storyteller, moral compass and symbolic worker can play a significant role in the process of mobilising people of faith in becoming involved in their environment and climate mobilisation. Keywords: Faith communities, Anthropocene, Spiritual formation, Climate narrative, Shared values, Shared symbols
Evaluating the Impact and Challenges of Farmer Producer Organizations on Agricultural Development in Jaipur District, Rajasthan, India
Authors: Yadav Mohan Lal , Dwivedi Pritesh , Kumar Amit
Published: May 2024

This paper examines the role of Farmer Producer Organizations (FPOs) in agricultural development, focusing on their impact on income, employment, and work activities alongside the prevalent challenges they face. Through a detailed analysis of survey data, the effectiveness of FPOs is evaluated in key areas such as food availability, healthcare, and education. Additionally, the study identifies critical barriers including financial access, policy constraints, and the need for technical training. By highlighting these issues, the research aims to provide insights into improving FPO operations and enhancing their contribution to sustainable agricultural growth, thus supporting farmer empowerment and economic development.
Prevalence of Orthopedic Injuries in Amateur Runners in the Municipality of Gurupi-To
Authors: Silva Kaio da Rocha , Cassimiro Kelly Cristina Nunes Silva , Araujo Warly Neves de , Almeida Márcio Araújo de , Almeida Thais Bezerra de , Noleto Cassia Alves de Carvalho , Neto Agrinazio Geraldo Nascimento
Published: May 2024

Aims: This study investigated the characteristics of orthopedic injuries in amateur runners, aiming to understand the factors that influence them.
Study Design: The research was conducted through a field study with a descriptive approach, combining quantitative and qualitative analysis of the collected data.
Place and Duration of Study: Data collection was carried out during the months of March and April 2024, in the city of Gurupi, Tocantins, Brazil.
Methodology: Using a quantitative approach, the responses of 103 participants regarding injury diagnoses, rest practices, behaviors during running, and frequency of fatigue were analyzed.
Results: Of the participants who responded to the questionnaire, 76 (74%) are male, while 27 (26%) are female. Of the 103 participants in the survey, 58 (56.3%) answered that they had not suffered any running-related orthopedic injury. However, the other 45 participants (43.7%) reported a variety of orthopedic injuries resulting from the practice of this sport. The results revealed a diversity of training practices and individual experiences, highlighting the lack of direct association between increased training volume and the occurrence of injuries. The research also identified different approaches to increasing pace/speed and distance during races, suggesting the need for individualized training programs.
Conclusion: This study highlights the complexity of the factors involved in orthopedic injuries related to road running and highlights the importance of personalized strategies in the prevention and treatment of these injuries, contributing to a safer and more sustainable sports practice for amateur runners.
Bacteriological Profile and Multidrug Resistance Patterns of Isolates from Sputum of Adults with Community Acquired Pneumonia in Diobu, Port Harcourt, Nigeria: A Retrospective Study
Authors: Ndukwu Chidi L.C. , Ikpeama Roseanne Adah
Published: May 2024

Community acquired pneumonia is a major global public health concern given its substantial contribution to the mortality and morbidity associated with infectious diseases, the huge losses in human and economic resources and the increasing challenges in treatment due to multidrug resistance (MDR). This retrospective cross sectional descriptive study reviewed laboratory records of adults clinically diagnosed with community acquired pneumonia (CAP) between January 1, 2017, and December 31, 2022. A total of 308 sputum specimens meeting the inclusion criteria were reviewed and yielded 135 (43.8%) bacterial strains. The 135 bacterial strains spread across 9 species had Streptococcus pneumoniae as the dominant species with 41(30.4%); followed by Staphylococcus aureus 21(15.6%), Escherichia coli 16(11.9%), Klebsiella pneumoniae 16(11.9%), Pseudomonas aeruginosa 12(8.9%), Streptococcus pyogenes 12(8.9%), Proteus mirabilis 10(7.4%), Enterobacter cloacae 5(3.7%) and Acinetobacter baumannii 2(1.5%). The cumulative resistance profile was 45.7%; the most resistant bacterial specie was Pseudomonas aeruginosa with a resistance profile of 50%; followed by Staphylococcus aureus (48.6%), Enterobacter cloacae (48.0%), Streptococcus pyogenes 47.5%, Streptococcus pneumoniae 47.3%, Klebsiella pneumoniae 45.6%, Proteus mirabilis 42.0%, Escherichia coli 40.0% and Acinetobacter baumannii 35.0%. The MDR prevalence was 85.9% including 36.3% extensively resistant strains; but no pan-drug resistant trains; while 14.1% were non-multidrug resistant. This study has contributed to the data on bacteriological profile and antimicrobial resistance patterns in aetiological agents of community acquired pneumonia in Port Harcourt. The high prevalence of drug resistance implies that many people are likely to be infected, while most of the antibiotics are losing potency against the bacterial pathogens. It is advised that regulatory laws on drug control be revised as it pertains antibiotics, the regulatory agencies should be compelled to perform their statutory duties while there is need to sensitize the populace on the dangers of antibiotic abuse and misuse.
Genetic Variability of Black Cumin (Nigella sativa L.) under Climatic Condition of Prayagraj
Authors: Singh Neeraj , Singh Devi , Wesley C. John
Published: May 2024

An Experiment on Black cumin was conducted during September to March 2023-2024, in horticulture Research field, Department of Horticulture, Naini Agricultural Institute, Sam Higginbottom University of Agriculture, and Technology & Sciences Prayagraj(UP) India. The results of the investigation, regarding the performance of the 7 variety of black cumin i.e. NS-44, NS-32, Ajmer Nigella-1, Ajmer Nigella-20, Azad kalonji, Local variety -1, Local variety- 2 obtained from different sources to find out the best performance in terms of growth and yield in Prayagraj agro-climatic conditions. The experiment was conducted in Randomized Block design, were each variety replicated thrice the results from the present investigation concluded that black cumin genotype Azad kalonji was recorded with maximum number of flowers/plant (78.33), Seed/ capsule (93.67), Seed yield (1.85 t/ha) and with maximum gross return, net return and cost Benefit Ratio of (3.75) which was found to be more productive and economically viable.
Osteonecrosis Related to the use of Osteoporosis Medications: An Integrative Literature Review
Authors: Santos Rafaela Melo , Almeida Edson Vinicius Santos , Fagundes Naiara Lima , Pires Laila Eduarda Silva , Ladeia Luiz Eduardo de Góes
Published: May 2024

Aims: Understand the relationship between bisphosphonates used in the treatment of osteoporosis and mandibular osteonecrosis, its outcomes, and implications for patient management, seeking to understand the best strategies for preventing and managing this condition.
Study Design:  Integrative literature review.
Methodology: The research methodology was outlined as exploratory and qualitative, aiming to provide a deeper understanding of the problem under study and generate hypotheses. Works published in the last 10 years (2014 to 2024) were used, including books, articles, periodicals, and online resources. For the selection of the sample, priority was given to works indexed in national and international journals, available in full. The electronic search was conducted in databases such as Latin American and Caribbean Health Sciences Literature (LILACS), Medical Literature Analysis and Retrieval System Online (MEDLINE), and Scientific Electronic Library Online (SciELO). The descriptors used were "Antiresorptive", "Bisphosphonate", "Mandible" and "Bone necrosis", registered in the Health Sciences Descriptors (DeCS), combined with the Boolean operators "AND" and "OR". The inclusion criteria for the selection of articles were to be original, addressing the theme of the study, to be indexed in the selected databases, written in Portuguese or English, and to be free of charge. Studies that were not related to the theme, duplicates and that did not fit into the proposed analysis period were excluded.
Results: Through the studies surveyed, an association between the incidence of osteonecrosis and the use of osteoporosis drugs, such as bisphosphonates, especially osteonecrosis of the jaws (ONJ), was observed. Bisphosphonates, widely used in the treatment of osteoporosis, inhibit bone resorption, but their long-term use is associated with complications, including ONJ. Risk factors such as advanced age, long-term use of medications, comorbidities such as diabetes, and genetic predisposition have been identified.
Conclusion: Management of ONJ involves conservative therapies and surgical procedures, which are especially effective when the condition is diagnosed early. On the other hand, therapeutic alternatives, such as photodynamic therapy, are being investigated, highlighting the need for controlled clinical trials to determine their efficacy.
SVM and RF Based Performance Enhancement in Organization: A Study on KGI, Odisha and its Organizational Growth
Authors: Sahoo Barsha Baishali , Dey Snehasis
Published: May 2024

Organization and organizational growth are two important aspects of a society and its relevant advancement. Now along with organization and its growth, the society advancement becomes most priority for the new age. Technologies that are becoming essential for these growths must have to be inculcated in new age society for complete advancement. Artificial intelligence, machine learning and deep learning are taking industry in a different horizon for complete globalization and adequate smarter than ever before. This paper dives into the organizational growth in particular having studied different aspects of making it even better and implementing different algorithms of AI/ML technologies to provide the best result for organizational growth. The Industry 4.0 has paved the way to build a strong organizational infrastructure for its sustainability in this competitive scenario. It is continuously leveraging different technologies and techniques to strengthen the growth. The next step is to adapt to the Industry 5.0 which works only with efficient robots and quantum computations. Researchers are searching and implementing every possible algorithm to its current infrastructure so as to produce effective results and methodologies that are best suited for fetching higher productivity. Artificial intelligence and Machine learning has produced immense growth in organizational success in recent times. The detailed study of Machine learning based algorithms in organizational growth is rapidly increasing in current years. Basically resource management, staff selection, training, monitoring and data analysis in an organization can be implemented with Machine learning algorithms for its complete growth. The challenge is to choose the proper algorithm from a specific learning technique and properly implementing it to the organization’s different aspects. In this paper basically Support vector machine (SVM) and random forest (RF) algorithms are analyzed and implemented to the specific organization KGI for effective resource management. The result is compared to get best suitable organizational infrastructure that is suited for industry 4.0.
A Comparative Analysis of Radioactive Material Concentrations in Natural Sources Linked to Mining in Niger using two Measurement Methods
Authors: Abdoullaziz Yacouba Souley , Almoustapha Aboubacar , Hassan Mohamed H.
Published: May 2024

In the present work, we report the results of radioactivity measurements carried out in soils from the COMINAK and SOMAIR mining areas, using normal mode gamma-ray spectroscopy (NMGS) and thermal neutron activation analysis (TNAA). Radio activities were determined for two series radionuclides (U-238 and Th-232) and one non-series radionuclide (K-40) from measured gamma-ray spectra. The activity concentrations of U-238 and Th-232 were respectively determined from the average nuclide concentration [Pb-214 (295.2keV ; 19.20%), Pb-214(351.9keV ; 37.10%), Bi-214 (609.3keV ; 46.90%), Bi-214 (1120.2keV; 15.04%) and Bi-214 (1764.49 keV; 15.90%)] and [Pb-212 (238.6keV; 43.6%), Pb-212 (300.09 keV; 3.18%), and Ac-228 (911.2keV; 25.8%), Ac-228 (968.9keV; 15.8%), Ac-228 (338.32 keV; 11.27%)]. The activity concentrations of K-40 are determined directly by measuring gamma-ray transitions at 1460.8keV (100%) using a high-resolution pure germanium detector with good efficiency from the Egyptian Atomic Energy Authority. We find that the result found in NMGS technique and TNAA technique for COMINAK soil sample for U-238 and Th-232 are 2.32mg/Kg, 2.36mg/Kg and 11.67mg/Kg, 11.72mg/Kg respectively the results are getting closer. In SOMAIR soil sample the result found for U-238 is getting closer 1.35mg/Kg and 1.34mg/Kg respectively for NMGS and TNAA and also for Th-232 the result is close 7.2mg/Kg and 7.87mg/Kg respectively for NMGS and TNAA. The results obtained confirm that one of the samples (COMINAK soil) is more radioactive than the SOMAIR soil samples, and the results are similar for both NMGS and TNAA techniques, with the exception of thorium in the SOMAIR soil sample. This study will help to assess the environmental impact around the mining areas.
Understanding the Right to Development among the People of Noida, Uttar Pradesh: A Case Study
Authors: Kumar Anoop , Ahmed Wakeel
Published: May 2024

Background: The exercise of a people's innate right to complete sovereignty over all of their natural resources and riches is included in the full realization of their right to self-determination, which is encompassed by the human right to development. It allows all people and communities to fully realize their basic freedoms and human rights by allowing them to engage in, contribute to, and benefit from advancements in the fields of economics, society, culture, and politics.
Aim: This study aims to assess the understanding of the right to development as a human right among the people.
Materials and Methods: A quantitative approach is employed in this research study to assess the understanding of the right to development as human rights. A descriptive survey research design with a sample size of 60, selected through purposive sampling based on specific inclusion and exclusion criteria, is utilized. Data is collected using a structured knowledge questionnaire and analyzed with descriptive and inferential statistics.
Results: The study evaluates the knowledge of the understanding of the right to development as human rights among the people of Noida, Uttar Pradesh. The analysis of knowledge levels is based on different demographic factors. Among the general population, 36 (60%) had average knowledge, 22 (36.7%) had good knowledge, and 2 (3.3%) had poor knowledge. The socio-demographic variable of educational status of the general population showed a statistically significant association with the knowledge level of understanding the right to development as human rights, while age, gender, and occupational status were not statistically significant (p < 0.05).
Association of self-reported pain with quality of life in resistant hypertensive patients / Associação da dor autorrelatada com a qualidade de vida no hipertenso resistente
Authors: Cantanhede Rodrigues Valeriana , da Silva Correia Dayse Mary , Rodrigues da Costa Kalliza Kary , Barci Dutra da Costa Luanna
Published: May 2024

Objetivo: analisar a associação da dor autorrelatada e a qualidade de vida de hipertensos resistentes no contexto da pandemia de Covid-19. Método: estudo transversal e analítico, realizado em hospital universitário, no período de janeiro a fevereiro de 2022. A coleta de dados deu-se por busca em prontuário e por contato telefônico, com a utilização dos Questionários de Dor de McGILL e Qualidade de Vida em Hipertensão Arterial (Minichal – Brasil). Na análise estatística foi usado o teste de Mann-Whitney e o coeficiente de Sperman (ρ). Resultados: predominância feminina (88,1%), com idade entre 50 e 70 anos (69,1%), com hipertensão arterial há mais de 20 anos (42,9%), estimativa de dor “leve a severa” (64,3%), boa qualidade de vida (47,6%), com associação significativa em hipertensos com colesterol total alto. Conclusão: identificação do perfil da amostra, associação da dor autorrelatada e a qualidade de vida de hipertensos resistentes no contexto da pandemia da Covid-19.
Energy Materials: Layered LaSrGa3O7‐Based Oxide‐Ion Conductors: Cooperative Transport Mechanisms and Flexible Structures (Adv. Funct. Mater. 22/2010)
Authors: Tealdi Cristina , Mustarelli Piercarlo , Islam M. Saiful
Published: November 2010

Novel melilite‐type gallium‐oxides are attracting attention as promising new oxide‐ion conductors with potential use in clean energy devices such as solid oxide fuel cells. Here, an atomic‐scale investigation of the LaSrGa3O7‐based system using advanced simulation techniques provides valuable insights into the defect chemistry and oxide ion conduction mechanisms, and includes comparison with the available experimental data. The simulation model reproduces the observed complex structure composed of layers of corner‐sharing GaO4 tetrahedra. A major finding is the first indication that oxide‐ion conduction in La1.54Sr0.46Ga3O7.27 occurs through an interstitialcy or cooperative‐type mechanism involving the concerted knock‐on motion of interstitial and lattice oxide ions. A key feature for the transport mechanism and high ionic conductivity is the intrinsic flexibility of the structure, which allows considerable local relaxation and changes in Ga coordination.
Neandertal postcranial remains from the Sima de las Palomas del Cabezo Gordo, Murcia, southeastern Spain
Authors: Walker Michael J. , Ortega Jon , López Mariano V. , Parmová Klára , Trinkaus Erik
Published: November 2010

The Sima de las Palomas, southeastern Spain, has yielded a series of Neandertal postcranial remains, including immature and mature isolated elements and the fragmentary partial skeleton of a young adult (Palomas 92). The remains largely conform to the general late archaic/Neandertal morphological pattern in terms of humeral diaphyseal shape, pectoralis major tuberosity size and pillar thickness, ulnar coronoid process height, manual middle phalangeal epiphyseal breadth, manual distal phalangeal tuberosity shape and breadth, femoral diaphyseal shape, and probably body proportions. Palomas 92 contrasts with the Neandertals in having variably gracile hand remains, a more sellar trapezial metacarpal 1 facet, more anteroposteriorly expanded mid‐proximal femoral diaphysis, and less robust pedal proximal phalanges. The Palomas Neandertals contrast with more northern European Neandertals particularly in various reflections of overall body size. Am J Phys Anthropol, 2011. © 2010 Wiley‐Liss, Inc.
Ein Meisterstück in der Synthese: wohldefinierte, multivalente und multimodale dendritische Architekturen für biomedizinische Anwendungen
Authors: Röglin Lars , Lempens Edith H. M. , Meijer E. W.
Published: November 2010

Dendrimere haben eine Reihe einzigartiger Eigenschaften, die sie zu interessanten Architekturen für biomedizinische Anwendungen machen. Bisher wurden multivalente und multimodale dendritische Strukturen überwiegend durch die statistische Modifikation der Endgruppen hergestellt. Ihre potenzielle Anwendung am Patienten verlangt dagegen nach wohldefinierten, monodispersen Materialien mit einer einheitlichen Struktur. Aktuelle Fortschritte in der chemischen Biologie und bei chemoselektiven Ligationsmethoden ermöglichen es nun, sich dieser Herausforderung zu stellen. In diesem Kurzaufsatz diskutieren wir die unterschiedlichen Synthesestrategien, einige Anwendungen, die diese neue Generation multivalenter und multimodaler Architekturen bereits nutzen, und die Herausforderungen für zukünftige Weiterentwicklungen.
Swelling study of superabsorbent PAA‐co‐PAM/clay nanohydrogel
Authors: Patra Subrata K. , Swain Sarat K.
Published: November 2010

A series of superabsorbent composites were prepared from acrylic acid (AA), acrylamide (AM), and Cloisite® 30B by aqueous solution polymerization technique using ammonium peroxodisulfate (APS) as initiator. The interaction of the organically modified nanoclay with PAA‐co‐PAM copolymer was verified by FTIR, whereas the morphology of the composite was studied by Scanning Electron Microscopy (SEM). The water absorbency in deionized water and saline water of the synthesized nanohydrogels was measured by calculating their percentage swelling ratio. The effects of copolymerization, monomer ratio, clay content, and temperature on the water absorbency were studied. The results indicated a considerable increase in swelling ratio by proper monomer proportion and incorporation of optimum clay percentage into the copolymer matrix. It was found that the nanohydrogel acquired highest water absorbency with 2% clay loading. The reswelling ability and water retention capacity of the PAA‐co‐PAM hydrogel and PAA‐co‐PAM/clay nanohydrogel were also measured. The water absorbency was found to increase after each reswelling for which it may be useful as recyclable superabsorbent material. The results of water retention capacity of the nanohydrogel were also encouraging and find application in agriculture, especially in drought‐prone areas. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Biosynthesis and degradation of the endocannabinoid 2‐arachidonoylglycerol
Authors: Ueda Natsuo , Tsuboi Kazuhito , Uyama Toru , Ohnishi Taira
Published: November 2010

2‐Arachidonoylglycerol (2‐AG) is a monoacylglycerol (MAG) molecule containing an esterified arachidonic acid chain at sn‐2 position of the glycerol backbone. Together with structurally similar N‐arachidonoylethanolamine (anandamide), 2‐AG has been extensively studied as an endogenous ligand of cannabinoid receptors (an endocannabinoid) in brain and other mammalian tissues. Accumulating evidence demonstrates that the endocannabinoid system, including the central‐type cannabinoid receptor CB1 and 2‐AG, is responsible for synaptic retrograde signaling in the central nervous system. As 2‐AG is rapidly formed from membrane phospholipids on cellular stimuli and degraded to arachidonic acid and glycerol, the enzymes catalyzing its biosynthesis and degradation are believed to play crucial roles in the regulation of its tissue levels. The major biosynthetic pathway appears to consist of sequential hydrolyses of inositol phospholipids via diacylglycerol (DAG) by β‐type phospholipase C and DAG lipase, while MAG lipase is a principal enzyme in the degradation. In this short review, we will briefly outline rapid advances in enzymological research on the biosynthetic and degradative pathways of 2‐AG.
Crystal Facet Dependence of Water Oxidation on BiVO4Sheets under Visible Light Irradiation
Authors: Wang Donge , Jiang Hongfu , Zong Xu , Xu Qian , Ma Yi , Li Guoling , Li Can
Published: November 2010

Monoclinic BiVO4crystals with preferentially exposed (040) facets were hydrothermally synthesized by using a trace amount of TiCl3as the directing agent; this function was confirmed by X‐ray diffraction patterns (XRD) and high‐resolution transmission electron microscopy (HRTEM). The effects of the directing agent TiCl3and the pH values applied during synthesis have been studied, and the optimized BiVO4sample with highly exposed (040) facet could be obtained by using 1.2 at. % of TiCl3as the directing agent at a pH value of 2. Some complementary techniques were also applied to exclude the effects of the structural and physical property changes, such as surface area and hydrophilicity. The photocatalytic activity of oxygen evolution on BiVO4is found to be proportionally correlated with the exposed surfaces of the (040) facet. It is assumed that the active sites with a BiV4structure on the exposed (040) facet is assigned to be responsible for the high activity of O2evolution.
Structural Effects of Fe3O4 Nanocrystals on Peroxidase‐Like Activity
Authors: Liu Shanhu , Lu Feng , Xing Ruimin , Zhu Jun‐Jie
Published: November 2010

The catalytic activity of nanocrystal catalysts depends strongly on their structures. Herein, we report three distinct structures of Fe3O4 nanocrystals, cluster spheres, octahedra, and triangular plates, prepared by a similar hydrothermal procedure. Additionally, the three Fe3O4 nanostructures were used as peroxidase nanomimetics and the correlation between the catalytic activities and the structures was first explored by using 3,3′,5,5′‐tetramethylbenzidine and H2O2 as peroxidase substrates. The results showed that the peroxidase‐like activities of the Fe3O4 nanocrystals were structure dependent and followed the order cluster spheres>triangular plates>octahedra; this order was closely related to their preferential exposure of catalytically active iron atoms or crystal planes. Such investigation is of great significance for peroxidase nanomimetics with enhanced activity and utilization.
Use of standard markers and incorporation of molecular markers into breast cancer therapy
Authors: Kaufmann Manfred , Pusztai Lajos ,   the Biedenkopf Expert Panel Members
Published: November 2010

Breast cancer is a heterogeneous disease of different subtypes on the molecular, histopathological, and clinical level. Genomic profiling techniques have led to several prognostic and predictive gene signatures of breast cancer that may further refine outcome prediction, especially in clinically equivocal situations. In particular, the predictive value of today's most important therapeutic targets, ER and HER2, are strongly influenced by the proliferative status of the tumor. Genomic assays are generally performed in a centralized manner, whereas routine pathological evaluation is mostly done on a decentralized basis, making the comparison of these methods difficult. Thus, there remains considerable uncertainty about the use of the new molecular markers in routine clinical decision making and their role in patient selection or stratification for future clinical trials. To address this concern, a group of representatives from breast cancer research groups in the areas of breast pathology, genomic profiling, and clinical trials critically reviewed all available data. Consensus recommendations are made on the practical use of molecular markers in breast cancer management and their incorporation into future clinical trials. Cancer 2011. © 2010 American Cancer Society.
Prognostic value of FLT3 mutations among different cytogenetic subgroups in acute myeloid leukemia
Authors: Santos Fabio P. S. , Jones Dan , Qiao Wei , Cortes Jorge E. , Ravandi Farhad , Estey Elihu E. , Verma Dushyant , Kantarjian Hagop , Borthakur Gautam
Published: November 2010

BACKGROUND:

The impact of FMS‐like tyrosine kinase 3 (FLT3) mutations and mutation burden among cytogenetic subgroups of patients with acute myeloid leukemia (AML) other than normal karyotype (NK) AML is unclear.

METHODS:

Patients with newly diagnosed AML were divided among 3 cytogenetic subgroups: core binding factor (CBF) AML, NK‐AML, and poor‐risk AML.

RESULTS:

In total, 481 patients were included: 13% had, CBF‐AML, 57% had NK‐AML, and 30% had poor risk AML, and the frequency of any FLT3 mutations was 20%, 32%, and 7.6% in the respective cytogenetic subgroups. FLT3 mutation did not have an impact on event‐free survival (EFS) in patients with CBF‐AML (P = .84) and poor‐risk AML (P = .37). In patients with NK‐AML, EFS was worse in the FLT3‐internal tandem duplication (ITD) group (20 weeks vs 41 weeks; P < .00,001) but not in the FLT3‐tyrosine kinase domain (TKD) point mutation group (61 weeks vs 41 weeks; P = .15). Worse EFS and overall survival (OS) were observed among patients with NK‐AML and higher FLT3‐ITD burden but not among patients with FLT3‐TKD mutation. In multivariate analysis, FLT3‐ITD mutation was prognostic of EFS in patients with NK‐AML (hazard ratio, 3.1; P = .03).

CONCLUSIONS:

FLT3 mutations did not have a prognostic impact in patients with AML who had good‐risk and poor‐risk karyotypes. In patients with NK‐AML, FLT3‐ITD mutations led to worse survival, which was even worse among patients who had high mutation burden. Cancer 2011. © 2010 American Cancer Society.
Sirtuin‐3 (SIRT3), a novel potential therapeutic target for oral cancer
Authors: Alhazzazi Turki Y. , Kamarajan Pachiyappan , Joo Nam , Huang Jing‐Yi , Verdin Eric , D'Silva Nisha J. , Kapila Yvonne L.
Published: November 2010

BACKGROUND:

Several sirtuin family members (SIRT1‐7), which are evolutionarily conserved NAD‐dependent deacetylases, play an important role in carcinogenesis. However, their role in oral cancer has not yet been investigated. Therefore, the objective of this study was to investigate whether sirtuins play a role in oral cancer carcinogenesis.

METHODS:

The expression levels of all sirtuins in several oral squamous cell carcinoma (OSCC) cell lines were compared with normal human oral keratinocytes and observed that SIRT3 was highly expressed. Therefore, tissue microarrays were used to evaluate the clinical relevance of this overexpression. SIRT3 down‐regulation in OSCC cell proliferation and survival was investigated and analyzed by using cell‐proliferation and cell‐viability assays. Ionizing radiation and cisplatin were used to investigate whether SIRT3 down‐regulation could increase the sensitivity of OSCC to both treatments. To further assess the in vivo role of SIRT3 in OSCC carcinogenesis, a floor‐of‐mouth oral cancer murine model was used to study the effect of SIRT3 down‐regulation on OSCC tumor growth in immunodeficient mice.

RESULTS:

The current results demonstrated for the first time that SIRT3 is overexpressed in OSCC in vitro and in vivo compared with other sirtuins. Down‐regulation of SIRT3 inhibited OSCC cell growth and proliferation and increased OSCC cell sensitivity to radiation and cisplatin treatments in vitro. SIRT3 down‐regulation also reduced tumor burden in vivo.

CONCLUSIONS:

The current investigation revealed a novel role for SIRT3 in oral cancer carcinogenesis as a promoter of cell proliferation and survival, thus implicating SIRT3 as a new potential therapeutic target to treat oral cancer. Cancer 2011. © 2010 American Cancer Society.
Association of cyclophosphamide use with dental developmental defects and salivary gland dysfunction in recipients of childhood antineoplastic therapy
Authors: Hsieh Susan Gyea‐Su , Hibbert Sally , Shaw Peter , Ahern Verity , Arora Manish
Published: November 2010

BACKGROUND:

The aim of this study was to examine the effect of antineoplastic therapy on dental development and saliva function in recipients of childhood antineoplastic therapy.

METHODS:

Patients attending the long‐term follow‐up clinic at Children's Hospital at Westmead, NSW, Australia, were included if they had received treatment prior to 16 years of age and were in remission for more than 5 years. A dental examination and saliva test were performed for each participant. Holtta's Defect Index (HDI) was used to assess tooth aplasia, microdontia, and root‐crown ratio on an orthopantomogram (OPG). Multivariable‐adjusted regression analyses were used to estimate the association of patient characteristics and treatment modalities with dental outcomes.

RESULTS:

One hundred six participants (61% male) were recruited (response rate = 88%). The mean HDI score was 24.7 ± 17.8. A cumulative dose of cyclophosphamide >7500 mg/m2 increased the HDI score by 13.06 (P = .01). Recipients of cyclophosphamide also had significantly increased odds of exhibiting very low saliva flow (<0.7 mL/min) (odds ratio = 12.43; 95% confidence interval, 2.08‐74.35; P = .006).

CONCLUSIONS:

Children and adolescents who received high doses of cyclophosphamide were at increased risk of dental disturbances. Cyclophosphamide recipients were also at greater risk of exhibiting very low saliva flow. This study applied the HDI to patients receiving all forms of antineoplastic treatment and highlights the dose‐dependent relation between cumulative dose of cyclophosphamide and dental disturbances. Cancer 2011. © 2010 American Cancer Society.
AJCC 7th edition of TNM staging accurately discriminates outcomes of patients with resectable intrahepatic cholangiocarcinoma
Authors: Farges Olivier , Fuks David , Le Treut Yves‐Patrice , Azoulay Daniel , Laurent Alexis , Bachellier Philippe , Nuzzo Gennaro , Belghiti Jacques , Pruvot François René , Regimbeau Jean Marc
Published: November 2010

BACKGROUND:

This year, the 7th edition of the AJCC staging manual has for the first time attributed a unique pTNM staging to intrahepatic cholangiocarcinoma (IHCC) that is intended to replace the 2 Western and ideally also the 2 Eastern systems currently in use. This proposal, which has not yet been validated, was tested in the current study.

METHODS:

Among 522 patients operated on with curative intent for an IHCC between 1994 and 2008 in tertiary hepatobiliary centers, those with mass‐forming‐type IHCCs, an R0 resection, and accurate pathological node staging were retained for evaluation. The distribution of these patients and their actuarial survival in the new TNM stages (as well as in the 4 previous ones) were compared.

RESULTS:

Only 163 patients fulfilled the inclusion criteria, mainly because of the lack of routine lymphadenectomy, but patients and tumors characteristics of this population were representative. These patients were evenly distributed between AJCC 7th edition stages (stage I, 28%; stage II, 32%; stage III, 35%), which was not the case for the other systems. With an average follow‐up of 34 months in survivors, the AJCC 7th edition was more discriminating than the others in predicting survival (median for stage I not reached; for stage II, 53 months, P = .01; for stage III, 16 months, P < .0001). Survival of these patients according to the 2 Japanese classifications was identical to that anticipated.

CONCLUSIONS:

The 7th edition is clinically relevant and may be applicable worldwide, provided routine lymphadenectomy at the time of surgery for IHCC becomes the standard of care. Cancer 2011. © 2010 American Cancer Society.