bluuebunny/crossref_metadata_2025 huggingface dataset:
Tautomerization reactions of thiobarbituric acid: A detailed kinetic study using combined TST and QTAIM approach
Authors: Fatahiyan Leila , Manesh Afshin Taghva , Masnabadi Nasrin
Published: August 2022

The kinetics of tautomerization reactions of thiobarbituric acid were
thoroughly investigated at the B3LYP/6-311+G(3df,2p) level of theory and
elevated temperatures from 270 K up to 1000 K. The kinetic parameters
were determined by employing canonical transition state theory (TST).
The quantum tunneling effect was included by both wigner and
centrifugal-dominant small-curvature semiclassical adiabatic
ground-state approximation methods. Intrinsic reaction coordinate (IRC)
analysis was performed to certify a unique connection from an obtained
transition state configuration to optimized structures of reactant and
product. The reaction forces and reaction force constants were computed
across the IRC of each reaction. Then, using extremums of reaction
forces, each reaction was partitioned into three stages containing
reactant, transition state, and product stages. The extent of reactions
was followed along with three reaction stages. The dependence of kinetic
parameters and curvature of Arrhenius plots on temperature were
investigated and discussed in the framework of TST. To further unveil
the mechanism of the reactions, the quantum theory of atoms in molecules
(QTAIM) was applied. To do this aim, QTAIM descriptors on the BCP of
involved bonds including the density of electrons, Laplacian of the
density of electrons, Lagrangian kinetic energy, potential energy, and
energy density were computed and surveyed along with reaction extent
through IRC.
Two regularity criteria of solutions to the liquid crystal flows
Authors: Li Qian , Yuan Baoquan
Published: August 2022

In this paper, we derive two regularity criteria of solutions to the
nematic liquid crystal flows. More precisely, we prove the local smooth
solution $(u, d)$ is regular if and only if one of the following two
conditions is satisfied: (i) $\nabla_{h}
u_{h}\in
L^{\frac{2p}{2p-3}}(0,T;
L^{p}(\mathbb{R}^{3})),\
\partial_{3} d\in
L^{\frac{2q}{q-3}}(0,T;
L^{q}(\mathbb{R}^{3})),\
\frac{3}{2}<
p\leq\infty,\ 3<
q\leq\infty$; and (ii)
$\nabla_{h} u_{h}\in
L^{q}(0,T;
L^{p}(\mathbb{R}^{3})),\
\frac{3}{p}+\frac{2}{q}\leq
1, \ 3
“IMPROVING FUNCTIONAL STATUS OF CHILDREN IN PALLIATIVE CARE WITH METRONOMIC CHEMOTHERAPY”
Authors: Melo Jorge Luis Ramírez , Llamas Norma Esthela , La-Cruz Andrea De , Urenda Xochilt Aurora Ramirez , Cueva Jessica Santoyo , Sanchez-Zubieta Feranando
Published: August 2022

Background: Children with incurable cancer can be treated with
metronomic chemotherapy. The aim of this study was to describe the
functional status in children with end-stage cancer who received
metronomic chemotherapy. Procedure: An observational cohort
study was designed with a convenience sample of patients younger than 18
years of age treated with metronomic chemotherapy between 2014-2020 at
Hospital Civil de Guadalajara in Mexico. Results: Forty-three
patients were included with a median age of 13 years. Metronomic
chemotherapy was indicated most frequently in patients with
lymphoblastic leukemia in ten cases (23.3%). Before metronomic
chemotherapy, more than 70% of patients had disease progression after a
second-line treatment. The median treatment duration was 4.2 months.
Treatment was suspended in 39 patients, of which 33 patients died. The
domain correlated with a lower score on the palliative performance scale
at diagnosis was described in 28 cases (65.1%) according to activity
level or evidence of disease, in 14 patients (32.5%) with ambulation,
and in one patient (2.3%) with intake. According to their score 28/43
(65%) patients presented improvement one month after starting
treatment. The McNemar test before and after one month of treatment with
metronomic chemotherapy was statistically significant for these symptoms
(P=0.00). We found that statistical significance was preserved during
the first three months (p = 0.016) of treatment. Conclusions:
The outpatient administration, good treatment adherence and few adverse
effects make metronomic chemotherapy a valuable treatment option. In our
experience, functional status improved significantly in the first three
months of treatment.
Outcomes Following Implementation of a Pediatric Cardio-Oncology Program
Authors: Daniels Zac , Olshefski Randal , Wright Lydia , Hart Stephen , Gajarski Robert , Hor Kan , Nandi Deipanjan
Published: August 2022

The comprehensive care that cancer patients require has become
increasingly complex and led to the creation of cardio-oncology clinics
(COC). Ninety-five patients were referred to our quaternary care COC.
Initiation of oral heart failure therapy (OHFT) or advanced cardiac
therapies within 1 year following referral were identified and risk
factors for these were evaluated. Patients older at the time of cancer
diagnosis and with lower LV ejection fraction were more likely to
require OHFT. COC’s elicit a high degree of clinically actionable
information for pediatric patients suffering from not only cancer, but
also cardiomyopathy, a particularly high-risk patient population.
Neutralizing antibodies against the SARS-CoV-2 ancestral strain and Omicron BA.1 subvariant in dogs and cats in Mexico
Authors: Solís-Hernández Mario , Dehesa-Freddy * , Roxana Pastrana-Unzueta , Nadia Carillo-Guzmán , Liljehult-Fuentes Francisco , Diego Pérez-De la Rosa Juan , Ramirez-Mendoza Humberto , Franco José Guillermo Estrada , Navarro-López Roberto , Hernández Jesús
Published: August 2022

The virus SARS-CoV-2 originated in Wuhan, China, in 2019 and has since
spread worldwide, infecting humans and animals. Several reports have
described the seroprevalence of antibodies in dogs and cats, but there
are no reports from Mexico. This study aimed to evaluate the
seroprevalence of neutralizing antibodies against the ancestral strain
and Omicron BA.1 subvariant in dogs and cats in Mexico. A total of 1111
samples from dogs (n=1052) and cats (n=59) were collected in different
regions of Mexico, and the presence of neutralizing antibodies (nAbs)
was evaluated by a plaque reduction neutralization test (PRNT90) and
microneutralization (MN). The results showed that 15.25% (9 of 59) of
cats and 2.85% (30 of 1052) of dogs presented nAbs against the
ancestral strain of SARS-CoV-2. However, the analysis of nAbs against
Omicron BA.1 in cats showed the same percentage of positive animals but
a reduction in the titer. In the case of dogs, 2.09% (22 of 1052)
showed nAbs against Omicron BA.1. These results agree with previous
reports showing that antibodies are more frequent in cats than in dogs
and that these antibodies have a lower capacity to neutralize Omicron
BA.1
Lorazepam in a schizophrenic patient with relapsing-remitting catatonia: A case report
Authors: Das Soumitra , Prasad Sakshi , Deva Sheryl , Sivashankari Thirunavukkarasu , Agyemang Francis , Sarangi Ashish
Published: August 2022

Significant element of recurrent catatonia is a history of brief
episodes separated by periodic relapses. Misdiagnosis of recurrent
catatonia can lead to inappropriate management. It has been associated
with mortality from dehydration, thrombosis, pulmonary embolism, and
pneumonia when untreated. Catatonia is responsive to benzodiazepines and
ECT regardless of the condition.
Cerebrotendinous xanthomatosis and infertility: a case report
Authors: Karimi Narges , Amiri Zahra , Naeini Sima , Okhovat Ali Asghar
Published: August 2022

Cerebrotendinous xanthomatosis is a lipid storage disorder that causes
neurological, ophthalmic, vascular, and musculoskeletal disorders due to
the deposition of cholesterol in the tissues. Hence, we report clinical
and imaging of a 31-year-old mentally retarded man with cerebellar
ataxia, bilateral swelling of the posterior aspect of Achill, and
infertility.
Testing Structuration Theory in E-Government System Assimilation: Mediating Role of Pakistani Cotton Ginners’ Absorption Capacity
Authors: Hassan Masood-Ul , Naz Farah , Ahmed Shakeel
Published: August 2022

Electronic Government (e-government) is a significant and vital application of the information and communication technologies (ICTs) to enable functional relations and communication with key government stakeholders. Governments have launched E-Government system for the basic objective of delivery and transfer of electronic information as well as services to their targeted citizens and for enhancing interaction with businesses and commerce. Therefore, assimilation and integration of E-Government systems in organizations is a strategic need. However, existing literature on E-Government system assimilation and meta-structures of organization (signification, domination, and legitimization) is limited. Therefore, in this paper, based upon structuration theory, we have developed a theoretical model with the aim to investigate the effect of organizational meta-structures of signification, domination, and legitimization on E-Government system assimilation with mediating effect of E-government absorption capacity. To test the proposed model, data collected from 292 ginning firms listed in the Pakistan Cotton Ginning Association (PCGA). The results confirm the direct relation between organizational meta structures and E-Government system assimilation and also support the mediating relationship of E-Government absorption capacity between the E-Government system assimilation and organizational meta structures. Moreover, the theoretical and managerial implications along with limitations and direction for future research also have been discussed in this study.
Workplace Bullying and Intention to Leave: The Mediating Role of Emotional Exhaustion
Authors: Khan Jawad , Ali Amna , Nisar Hena Gul
Published: August 2022

Bullying at work and its impact on employees' intention to leave are the focus of this study. Specifically, this research aims to determine the link between workplace bullying and emotional exhaustion and the intention to leave. Data were gathered from 234 employees working in the Saif group of Pakistan through questionnaires. The study sample was drawn using the convenience sampling technique. The non-probability sampling technique was used because of the Covid 19 situation; as per government notification, only 50% of the staff was present in the offices. This study used SPSS V. 25 for direct relationships, Hayes model 4 for mediation analysis, and for model fitness, we used CFA (Amos 22). The results show that workplace bullying has a statistically significant and positive impact on the intention to quit and emotional exhaustion plays a significant role in mediating this connection (β=0.38***, SE=0.074, LLCI=0.3077 and ULCI=0.6176). Based on these results, we conclude that workplace bullying is a mayor cause of employees' exhaustion and compels them to depart from an organisation at some point. In light of these results, supervisors or line managers play a vital role in organisational sustainability by retaining skilful employees by making the workplace environment friendly and cooperative in the long run.
Uncertainty Analysis of Multicomponent Elastic Inversion of Thin-Layers
Authors: De Franco Allan Peixoto , Oliveira Sérgio Adriano Moura , Moraes Fernando Sergio
Published: August 2022

ABSTRACT. We assessed the effectiveness of seismic inversion in estimating the elastic properties of layers whose thickness represents a fraction of the wavelength. We used an approach that integrates a quantitative study of inversion uncertainties based on the stochastic Bayesian method and sensitivity analysis, considering the full waveform seismic response of the layer model. Three inversion input data combinations PP, PS, and joint PP-PS reflections provide comprehensive information for the analysis. Estimates of Vp, Vs, and the density of thin layers are sensitive to the intensity of the elastic property contrasts and incidence angle coverage. Results show that the elastic parameters of layers as thin as 1/16 of the peak wavelength can be estimated with low uncertainty if the input data contain incidence angles up to 40 degrees for the PP-PS case and up to 55 degrees for the PP case, when the elastic property contrast is not small.Keywords: stochastic inversion; reflectivity method; sensitivity analysis. Análise de Incertezas da Inversão Elástica Multicomponente de Camadas FinasRESUMO. Nós avaliamos a eficácia da inversão sísmica na estimativa das propriedades elásticas de camadas cuja espessura representa uma fração do comprimento de onda. Utilizamos uma abordagem que integra um estudo quantitativo de incertezas de inversão baseado no método estocástico Bayesiano e análise de sensibilidade, considerando a resposta sísmica completa da forma de onda do modelo de camadas. As análises foram realizadas em três combinações de dados de entrada para inversão: PP, PS e reflexões PP-PS conjuntas. As estimativas de Vp, Vs e densidade de camadas finas são sensíveis à intensidade dos contrastes de propriedades elásticas e à cobertura do ângulo de incidência. Os resultados mostram que os parâmetros elásticos de camadas tão finas quanto 1/16 do comprimento de onda de pico podem ser estimados com baixa incerteza se os dados de entrada contiverem ângulos de incidência de até 40 graus para o caso PP-PS e até 55 graus para o caso PP, quando o contraste da propriedade elástica não é pequeno.Palavras-chave: inversão estocástica; método da refletividade; análise de sensibilidade.
TBK1-mTOR Signaling Attenuates Obesity-Linked Hyperglycemia and Insulin Resistance
Authors: Bodur Cagri , Kazyken Dubek , Huang Kezhen , Tooley Aaron Seth , Cho Kae Won , Barnes Tammy M. , Lumeng Carey N. , Myers Martin G. , Fingar Diane C.
Published: August 2022

The innate immune kinase TBK1 (TANK-binding kinase 1) responds to microbial-derived signals to initiate responses against viral and bacterial pathogens. More recent work implicates TBK1 in metabolism and tumorigenesis. The kinase mTOR (mechanistic target of rapamycin) integrates diverse environmental cues to control fundamental cellular processes. Our prior work demonstrated in cells that TBK1 phosphorylates mTOR (on S2159) to increase mTORC1 and mTORC2 catalytic activity and signaling. Here we investigate a role for TBK1-mTOR signaling in control of glucose metabolism in vivo. We find that mice with diet-induced obesity (DIO) but not lean mice bearing a whole-body “TBK1-resistant” Mtor S2159A knock-in allele (MtorA/A) display exacerbated hyperglycemia and systemic insulin resistance with no change in energy balance. Mechanistically, Mtor S2159A knock-in in DIO mice reduces mTORC1 and mTORC2 signaling in response to insulin and innate immune agonists, reduces anti-inflammatory gene expression in adipose tissue, and blunts anti-inflammatory macrophage M2 polarization, phenotypes shared by mice with tissue-specific inactivation of TBK1 or mTOR complexes. Tissues from DIO mice display elevated TBK1 activity and mTOR S2159 phosphorylation relative to lean mice. We propose a model whereby obesity-associated signals increase TBK1 activity and mTOR phosphorylation, which boost mTORC1 and mTORC2 signaling in parallel to the insulin pathway, thereby attenuating insulin resistance to improve glycemic control during diet-induced obesity.
REDD1 Ablation Attenuates the Development of Renal Complications in Diabetic Mice
Authors: Sunilkumar Siddharth , Yerlikaya Esma I. , Toro Allyson L. , Miller William P. , Chen Han , Hu Kebin , Kimball Scot R. , Dennis Michael D.
Published: August 2022

Chronic hyperglycemia contributes to development of diabetic kidney disease by promoting glomerular injury. In this study, we evaluated the hypothesis that hyperglycemic conditions promote expression of the stress response protein regulated in development and DNA damage response 1 (REDD1) in the kidney in a manner that contributes to the development of oxidative stress and renal injury. After 16 weeks of streptozotocin-induced diabetes, albuminuria and renal hypertrophy were observed in wild-type (WT) mice coincident with increased renal REDD1 expression. In contrast, diabetic REDD1 knockout (KO) mice did not exhibit impaired renal physiology. Histopathologic examination revealed that glomerular damage including mesangial expansion, matrix deposition, and podocytopenia in the kidneys of diabetic WT mice was reduced or absent in diabetic REDD1 KO mice. In cultured human podocytes, exposure to hyperglycemic conditions enhanced REDD1 expression, increased reactive oxygen species (ROS) levels, and promoted cell death. In both the kidney of diabetic mice and in podocyte cultures exposed to hyperglycemic conditions, REDD1 deletion reduced ROS and prevented podocyte loss. Benefits of REDD1 deletion were recapitulated by pharmacological GSK3β suppression, supporting a role for REDD1-dependent GSK3β activation in diabetes-induced oxidative stress and renal defects. The results support a role for REDD1 in diabetes-induced renal complications.
Analysis of Mechanisms Involved in Ventricular Assist Device (VAD) Induced Extracellular Vesicle Generation and their Cellular Effects
Authors:   , James Rebecca L.
Published: August 2022

Heart failure is a major global health issue, carrying a significant risk of morbidity and mortality. The current gold standard treatment for end-stage heart failure is heart transplantation. However, with reduced availability of viable organs, and a non-sustainable treatment strategy, alternate mechanisms are being sought to prolong life. Ventricular assist devices (VADs) offer a potential life-extending treatment, however, do not come without adverse events. Therefore, it is vital to understand and reduce these side effects in order to maximise patient quality of life. More recently, extracellular vesicles (EVs) have increased in popularity amongst various scientific disciplines. EVs are small (<1000 nanometre) membrane-bound packages secreted from all cell types, which are known to have roles in both health and disease. However, there is limited knowledge into the roles of EVs in VAD patients. Therefore, this study investigated the prevalence, origin and roles of EVs concerning VADs. One significant challenge facing EV research is the isolation and detection of EVs, which increases in complexity when assessing EVs in biological fluids that contain numerous components. This study began by assessing the most commonly used isolation and detection techniques and tested their applicability to blood plasma, with mixed results. We demonstrated the need for diluting higher viscosity fluids prior to EV extraction. Secondly, this study displayed the increased prevalence of EVs produced by both leukocytes and platelets exposed to elevated levels of non-physiological shear stress both in vitro and in vivo. We display the effect of VADs as a perpetuating factor in EV production and demonstrated the potential use of EVs as a means of diagnostics in adverse events, to aid in mitigating VAD patient outcomes. Finally, we presented the detrimental effects of elevated pathological EVs in patient prognosis. We assessed cargo alterations within EVs present in both healthy and pathological blood and determined downstream effects. Here, increased levels of leukocyte and platelet EVs are shown to have the potential to induce inflammation and cellular activation. Conversely, we also revealed the therapeutic and disease mitigating potentials of healthy EVs. In conclusion, this study has provided a consensus on the protocol for EV isolation from plasma and a platform for EV research in relation to heart failure and VAD patients. Furthermore, we show VAD shear stress as a significant instigator of EV release. Subsequently, we demonstrate the possibility of healthy EVs in limiting pathological processes. Therefore, this research successfully highlighted the significant impacts of EVs in VAD patients, which can be utilised to improve patient outcomes.
Changing Landscapes of Time and Space: the Bristol Channel Region c.1790-1914
Authors:   , Baker Robert
Published: August 2022

The thesis considers how perceptions of time and space changed during this period in the Bristol Channel region as new forms of transport and communications stimulated an unprecedented movement of people, freight and messaging at speeds which appeared to compress space, bringing the outside world closer. Newspapers are used as the principal primary source, and, as expressions of locality, they provide an insight into the diverse mental landscapes concerning speed and space that were emerging across the region. The region was on the margins of Great Britain prior to these changes, but new transport and communications networks brought the region into the mainstream. New forms of transport and communications tended to favour urban areas and the experience of rapid movement was uneven across the region. The revolution in individual travel and passenger transport was populated principally by men, with the exceptions of the railway excursion and the urban tram, which expanded the horizons of leisure for working classes, but the level of railway fares excluded many potential working-class travellers. Perceptions of time and space, therefore, did not only vary between locations across the region, but also between men and women and social classes as they experienced travel differently. The railway and telegraph, Britain’s ‘nervous system’, connected the region with markets throughout the British Isles and globally. Steamships forged ‘ocean highways’ and telegraph cables bounded the planet, creating an international communications system that also standardized ‘railway’ time everywhere. As the outside world became more accessible, nearer and more connected, new forms of landscapes regarding place, identity and ‘others’ were defined as a measure of human progress. These changes helped define what is meant by ‘modern’; but they originated in industrial change from the 1790s which was made possible by new technologies in transport and communications.
Paralelos entre “o conto da Aia” e o Direito Internacional: responsabilização internacional de Gilead?
Authors: Turra Karin Kelbert
Published: August 2022

O presente trabalho se propõe a realizar comparações entre institutos do Direito Internacional e situações abordadas na narrativa fictícia de “O Conto da Aia”. Em um futuro distópico em que os Estados Unidos sofrem um golpe político de uma seita religiosa que baseia suas leis no antigo testamento da Bíblia, inúmeras práticas ilegais ocorrem nesse cenário. Inicialmente, nos proporemos a verificar a condição de Gilead como Estado, na perspectiva do Direito Internacional. Posteriormente, serão abordadas as violações de direitos humanos observadas no enredo. Por fim, objetiva-se verificar a possibilidade de responsabilização internacional do Estado, no caso analisado. Para tanto, serão utilizados argumentos doutrinários, bem como legislações de Direito Internacional, objetivando fundamentar a discussão ora proposta.
A Legalidade das Operações de Targeted Killings à luz do Direito Internacional
Authors: Albuquerque Leonardo Neves de
Published: August 2022

Os ataques de 2001 ao World Trade Center, nos Estados Unidos, foram o estopim da adoção de uma política antiterrorista incisiva, não apenas no país norte-americano, mas em todo o mundo. Os governos promulgaram instrumentos legislativos conferindo maiores poderes ao Executivo e reduzindo a responsabilidade pelas consequências de seus atos. O uso da força como agente preventivo, no âmbito das políticas de antiterrorismo, deve-se ao fato de estas medidas, até atualmente, serem realizadas sem o devido crivo judicial e público. Desde a morte de Osama Bin Laden, sob a gerência de Barack Obama, até a execução de Qasem Soleimani, por ordem de Donald Trump, os targeted killings se provaram uma arma eficaz contra os inimigos de Estado. O que fez deles uma pauta recente, contudo, foram os recentes desenvolvimentos tecnológicos de drones de combate, que permitem uma execução quase infalível de ataques remotos. Dessa forma, o presente artigo se propõe a responder às seguintes perguntas: as operações de targeted killings podem ser legais à luz do Direito Internacional? Se sim, sob qual regime jurídico isso seria possível? Para respondê-la o trabalho definirá, primeiramente, os termos principais, procedendo ao estudo dos regimes legais aplicáveis a estas operações, como a lei do uso da força (jus ad bellum), o Direito Humanitário Internacional (DHI) e, por fim, o Direito Internacional dos Direitos Humanos (DIDH). Após, fará uma análise das disparidades entre tais regimes a fim de demonstrar que o modelo ideal é o de DIDH. Finalmente, o artigo concluirá pela legalidade dos targeted killings, desde que seguidos os critérios adicionais formulados para aferir a legitimidade das operações na ótica do DIDH.
Bitributação Decreto nº: 10.714 de 2021, Brasil e Suíça para eliminar a Dupla Tributação da Renda e Prevenir a Evasão e a Elisão Fiscal.
Authors: Maranhão Levi Alexandrino
Published: August 2022

Neste breve trabalho estudaremos o tratado Decreto nº 10.714, que tem por objetivo evitar a dupla tributação internacional e reduzir a evasão e a elisão fiscal, analisando os principais pontos do tratado e seus respectivos artigos. Não restam dúvidas que o tratado celebrado entre o Brasil e a Suíça beneficiará de forma igualitária o Estado e o Contribuinte, que agora terá efetiva segurança no que tange a declaração tributária em âmbito internacional, reduzindo em contra partida, a evasão e a elisão fiscal.
Aplicação De Soft Law no Direito Internacional
Authors: Nogueira Carolina
Published: August 2022

Os vastos efeitos ambientais, sociais e econômicos da atuação empresarial no mundo globalizado trazem à tona a importância do direito internacional da proteção ao meio ambiente e da aplicação de práticas ESG por empresas transnacionais. O chamado hard law, no que se refere ao assunto ambiental e ESG, nem sempre acompanha as evoluções econômicas e sociais da economia globalizada – por isso, os mecanismos de regulação de adesão voluntária (soft law) muitas vezes são mais eficazes para a aplicação de padrões de qualidade internacionais e para a proteção dos interesses difusos.
DAKWAH BERBASIS BUDAYA LOKAL STUDI IMPLEMENTASI NASKAH PENGOBATAN FUADI AMRI DI KECAMATAN KELUMBAYAN KABUPATEN TANGGAMUS
Authors: Sari Jenila , Shonhaji Shonhaji , Yanti Fitri
Published: August 2022

Da'wah is an effort to invite, convey, and spread the truth to the community to carry out the teachings of Islam according to the guidance of the Qur'an and the Sunnah of the Prophet Muhammad SAW. The cultural da'wah approach in the form of Medical Manuscripts is carried out in the Kelumbayan District community who still carry out the Hindu-Buddhist tradition. This study aims to reveal the implementation of Fuadi Amri's treatment script in Kelumbayan District and the results. This research is a qualitative descriptive field research. Data sourced from primary data and secondary data. Data collection techniques consist of interviews, observations, and documentation, as well as data analysis by collecting data, data reduction, data presentation, and conclusions. The results of the research on the implementation of the treatment script carried out by Fuadi Amri in Kelumbayan District were a process of deliberation, providing advice and guidance, instructing patients and their families to do dhikr and prayer, and provide final motivation. The result of the implementation of the Medical Manuscript is the achievement of the goals of da'wah both practical, realistic, and idealistic. Preservation of local culture with its usefulness, as well as uniting a multicultural society.Keywords: Da’wah, Local Culture, Treatment Script
PERSPEKTIF MASLAHAH TERHADAP PERTIMBANGAN HAKIM PADA PUTUSAN PERKARA NOMOR: 1376/Pdt.G/2019/PA.Tnk TENTANG PENETAPAN HAK HADANAH KEPADA IBU KANDUNG
Authors: Jayusman Jayusman , Huda Nurul
Published: August 2022

The protection of women and children is one of problems in the Indonesian judiciary. In the decision on Case Number: 1234/Pdt.G/2018/PA.Tnk and Number: 0014/Pdt.G/2019/PTA. Bdl which has permanent legal force regarding child custody by the Plaintiff. However, the Defendant was reluctant and did not want to implement the decision. So the Plaintiff must file a new lawsuit for the execution of the previous decision with decision number: 1376/Pdt.G/2019/PA.Tnk. The problem with this article is based on the judge's consideration of decision number: 1376/Pdt.G/2019/PA.Tnk regarding the determination of child custody to his biological mother. This research is library which is descriptive analytical. The primary data is in the form of decision number: 1376/Pdt.G/2019/PA.Tnk and is complemented by secondary data. Data were collected through documentation techniques and the analysis was carried out since the data collection process and deductively. The results of this study indicate that the judge's consideration in the case decision Number: 1376/Pdt.G/2019/PA.Tnk regarding the determination of child custody to the biological mother is based on the benefit and goodness of the child. The declarative nature of the previous decision prevented the realization of benefit values for the parties. The reason usually regarding child custody are executed voluntarily and not by force. The plaintiff seeks to obtain the power of legal execution from the previous decision by filing a new lawsuit with a comdennatoir decision, so that the child can be handed over to him to be treated as well as possible.Keywords: Maslahah, Comdemnatoir, Declaratoin
TEO-SOSIOLOGI SEBAGAI BASIS MODERASI BERAGAMA DI TENGAH PANDEMIK COVID 19
Authors: Muhtador Moh
Published: August 2022

In early 2020, the world was shocked by the outbreak of the corona virus (covid 19) that emerged in Wuhan, China and quickly spread to the rest of the world, including Indonesia. The pandemic that occurred in Indonesia tested citizens who are known to be multicultural with religion, language, culture, religion, ethnicity and race from the aspect of spirituality (divinity) and social (humanity), because covid 19 does not look at social and religious strata. Therefore, it is necessary to read religious moderation as a discourse in multicultural life in Indonesia as a mainstream in growing spirituality and social life. This article is a qualitative literature study with techniques for collecting data from several sources such as online news, journal articles and phenomena related to religious issues and COVID-19 which are analyzed with Islamic theological theory and sociology, to get a comprehensive reading of moderation. religion during a pandemic. First, theologically it is believed that God is the center of the cosmos which is to grow faith with the representation of the Spirit and can interpret theology inclusively. Second, in the context of Indonesia, it is sociologically aware that the spread of religion is not carried out by means of violence and that religion and culture act as social capital.Keywords: Religious Moderation, Pandemic, Theo-Sociology
Analysis Of Basic Teachers Professionality In Improving Creativity In The Digital Era
Authors: Iskandar Rossi , MS Zulela
Published: August 2022

The purpose of this study is to describe the professional competence of teachers in increasing creativity in the digital era. The research method used in this research is qualitative with the type of library research, which is a series of studies relating to the library data collection method, or research where the object of research is explored through a variety of library information with a philosophical and pedagogical approach. The results showed that to drive better change in the world of education with a priority to increase the quality of teachers, it is necessary to have teachers who are creative and have the quality to bring change and innovation both academically and non-academically. Creative teachers always develop diverse learning activities. The learning process in front of the class for creative teachers does not only deliver material but has a sense of responsibility to guide, create, experiment, inspire, and motivate students to continue to be creative.
University academic journal and annual research-to-practice conference for graduate and postgraduate students: Cooperation problems
Authors: Lunkina Yu. V.
Published: August 2022

Research-to-practice conference, the theme of which matches the content of one or several journal sections, is considered as one of ways to solve the problem of new authors’ calling to the journal. On the one hand, the role of conference’s media partner is an element of journal promotion. Оn the other hand, the partnership with University conference for graduate and postgraduate students imposes additional load on editorial staff. When their workload is already high in a routine mode, they delegate conference papers’ editing and prepress to authors that can’t ensure high quality of publications. Moreover, if conference papers are published simultaneously with publication of journal articles based on conference reports the problem of text authenticity arises (i.e. self-plagiarism). These circumstances cause journal staff to doubt whether participation in university conferences as media partner makes sense.
Choosing a language strategy for a top-rated Russian academic journal
Authors: Kuznetsova T. Yu. , Silnichaya A. V. , Evgrafova A. O.
Published: August 2022

Increasing citation and improving the impact factor is a challenging task for both authors and scientific journals. It is particularly so for Russian journals indexed in international scientometric databases, including Web of Science and Scopus. This study shows that researchers consider inefficient language strategies to be one of the main reasons for poor international outreach. This article explores    the strategies of several Russian journals indexed in Scopus as of March 2022, identifies their advantages and disadvantages as well as the subsequent risks. The study offers recommendations for choosing an optimal language strategy, including the one aimed at increasing citation in international and national databases and promoting rated Russian journals internationally. Based on the analysis of the journals indexed in the Scopus database, six linguistic models have been identified. The study has shown that the bilingual format – publishing in Russian and English – provides the best visibility at the national and international levels.
Resolution of the 10th International Scientific and Practical Conference “World-Class Scientific Publication – 2022: from the present to the future”, Moscow, 26-29 April 2022
Authors: Евграфова А. О. , Медведева О. О.
Published: August 2022

Конференция была направлена на обсуждение актуальных вопросов развития российских научных журналов в современных условиях, достижения ими более высокого национального и международного уровней, определения места в решении задач популяризации и продвижения результатов научной деятельности, в создании национальной системы оценки результативности научных исследований и разработок, сохранения и повышения позиций в международных информационных системах.
The potential of private universities in promotion of national science: Current status and trends
Authors: Polikhina N. A.
Published: August 2022

In the presented material the potential and capabilities of private universities in development and promotion of Russian science is analyzed based on information from the Web of Science Core Collection and RSCI databases. A definition of the concept of “private university”, used at the international and national levels, is given, as well as statistics on the number of private universities in Russia and the share of academic staff working in them. A comparative analysis of quantitative and qualitative scientometric indicators of authors affiliated with private and public universities is carried out. The dynamics of the indicators of scientific journals affiliated with private universities during 2017–2020 is studied. The conclusion is drawn that private universities not only possess scientific potential, but also have real tools to promote scientific results of national science.
COPE Flowcharts and infographics – Changes in authorship. Addition of extra author – before publication
Authors: Editorial Article
Published: August 2022

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COPE Flowcharts and infographics – Changes in authorship. Removal of author – after publication
Authors: Editorial Article
Published: August 2022

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Impact of peer review institute on scientific maturity of Russian journals
Authors: Myslyakova Yu. G.
Published: August 2022

The article is devoted to the development of the institute of peer review considered in the context of influencing the scientific maturity of periodicals. The choice of this topic is due, on the one hand, to new scientific and technological trends in the sustainable development of the national economy, on the other, to the upcoming information isolation, the onset of which has a high probabilistic character and serious negative consequences for Russian magazines. Therefore, Russian periodicals should be ready for any development of events and have an adaptation potential for new economic realities, i.e. to be scientifically mature. The article proposed an author’s understanding of the definition “scientific maturity” of the journal and revealed the peculiarities of peer review that determine it. The article also presents the results of a survey conducted by Institute of Economics of the Ural Branch of RAS and the Association of Scientific Editors and Publishers, among representatives of Russian journals of economic, social, technical, humanitarian, medical sciences, which make it possible to identify general trends and patterns of formation of the peer review institute in Russia. The author’s rapid analysis of respondents’ responses made it possible to form a fundamental basis for the development of fundamentally new options for improving the work of publishers with reviewers, including the selection of experts based on a single database of reviewers. It gives the process of assessing the quality of the content of articles an interdisciplinary nature, as well as flexibility and higher performance.
Retraction of duplicate articles in scientific journals: The experience of a regional university
Authors: Afanas’eva Yu. L.
Published: August 2022

The article describes the experience of the editorial board of scientific publications at Penza  State University in retracting duplicate publications. It provides a practical example illustrating the problems that arise at each stage of the retraction process. It shows that a significant part of these problems lies in the legal field and requires founders and publishers to be aware of the norms of the current legislation not only in the field of intellectual property, but also in the field of protecting the honor, dignity and business reputation of authors.
Understanding leptospirosis: application of state-of-the-art molecular typing tools with a One Health lens
Authors: Sykes Jane E. , Gamage Chandika D. , Haake David A. , Nally Jarlath E.
Published: August 2022

Leptospirosis is an archetypal One Health problem as described in the companion Currents in One Health article in the October 2022 issue of the Journal of the American Veterinary Medical Association by Sykes et al. A thorough understanding of leptospirosis requires a detailed analysis of the elaborate interplay among pathogenic leptospiral strains, host species, and the environment. Such an understanding is required to inform appropriate preventative measures including vaccine design, prophylaxis efforts, educational programs that help to reduce exposure to pathogenic spirochetes, as well as policy development. Because of the complex epidemiology of leptospirosis, a One Health approach as defined by the One Health Initiative Task Force is critical—an approach that calls for “the collaborative efforts of multiple disciplines working locally, nationally, and globally, to attain optimal health for people, animals and our environment.” Over the last three decades, progressive advances in cutting-edge molecular typing techniques, as well as our ability to rapidly generate and share large amounts of sequence data through establishment and growth of databases, have been central to accelerating a One Health understanding of the epidemiology of leptospirosis. Nevertheless, our dependence on serotype information because of the serovar-specific nature of current vaccines means that laborious serotyping efforts continue. With the advent of new approaches such as mRNA vaccines that are based on lipopolysaccharide immunogens, sequence- and/or proteomics-based typing methods may replace these methods.
What the Latest Physical Science of Climate Change Means for Cities
Authors: Gallardo Laura , Hamdi Rafiq , Islam A.K.M. Saiful , Klaus Ian , Klimont Zbigniew , Krishnaswamy Jagdish , Pinto Izidine , Otto Friederike , Raghavan Krishnan , Revi Aromar , Sörensson Anna A , Szopa Sophie
Published: August 2022

The 6 th Assessment Report cycle of the Intergovernmental Panel on Climate Change (AR6) comes at a precipitous moment in history. Human influence has warmed the planet, and widespread and rapid impacts are occurring to natural and human systems in all regions of the world. In response, immediate action is needed if there is to be any hope of limiting global warming to 1.5°C or well below 2°C below pre-industrial levels, as well as preparing for and adapting to current and future risks. The transformations needed in response to climate change will require decisive action in cities and urban areas. Cities and urban areas are a major source and driver of emissions; they are also crucial sites for system transitions in the near term and transformations over longer time frames
The Existence of the Yellow Book in the Digital Era: Study in Dayah Aceh
Authors: Meriza Iin , Febriani Asra , Tisa Mutia , Nurdin Muhammad Riza
Published: August 2022

The existence of the yellow book is very important for Islamic boarding schools or dayahs in Aceh. Every religious lesson must use the yellow book as the main reference for teachers in teaching. The yellow book has been used for centuries in the study of dayah. However, the existence of internet media in the current digital era has an effect on learning patterns in the dayah environment. The yellow book as a learning resource in the dayah faces the challenges of the digital era media that is able to answer various people's problems quickly. In the digital era, the public and students can access information related to Islamic teachings via the internet quickly, cheaply and easily. The purpose of this study is to find out and describe the existence of the yellow book in the digital era (study in dayah aceh). This research is a field research with a qualitative descriptive method. The results show that the yellow book still exists in the current digital era and remains a mandatory reference in the dayah curriculum, but the progress of the digital era continues to color the pesantren curriculum treasures with the finding that Guree Dayah uses the Maktabah Syamilah feature as a supporting reference. Furthermore, in responding to advances in information technology, dayah utilizes the internet as a medium of da'wah and socialization of dayah as well as reviewing legal issues encountered by the public on the internet by referring to the yellow book
Maqashid al-Syari’ah al-Syatibi: In The Paradigm Muslim Society as Methodology of Zakat Law
Authors: Khoiri Nispul , Harahap Ikhwanuddin , Latif Mohd Syahiran Abdul
Published: August 2022

This research is collaborative research of library research and field research. Using a qualitative method with a normative legal approach, namely Islamic law (usul fiqh) and naturalistic phenomena. Research exploring the existence of Regional Regulations (Perda) on Zakat Management in Medan City is a necessity, to explore the potential for greater zakat, but the Perda in question has not yet been legislated. The many inhibiting factors, two factors need attention in this study, namely: First, the paradigm of the Muslim community in the city of Medan towards the Syafii fiqh legal methodology is since the majority of Muslims are based on the Syafii fiqh school, thus denying other legal methodologies such as Maqashid al-Syariah which are quite relevant to strengthening the zakat regulation. Second, the paradigm of the Muslim community in the city of Medan has not seen the urgency of Maqashid al-Syariahal-Syatibi as an element of strengthening the regional regulation on zakat in Medan City. The results of the study show that: First, the Muslim community of Medan city does not yet know and fully understand Maqashid al-Syariah al-Syatibi as a legal methodology, because of the strong and strong Syafii school of jurisprudence as a single majority school. Second, Maqashid al-Syariah al-Syatibi is urgent as a solution to strengthening the regional regulation on zakat in the city of Medan with the substance of high benefit aspects, starting from the position of regulation, management to positive benefits for the Muslim community in the city of Medan
Peranan Indonesia Dalam Mewujudkan Keamanan Maritim Di Kawasan Asean
Authors: Medina Dayu , Enggriyeni Dewi
Published: August 2022

United Nation Convention Law of The Sea (UNCLOS 1982) regulates maritime boundaries, rights and obligations of coastal states, and maritime security. This article aims to find out about how the role of Indonesia to realize maritime security in ASEAN areas. Maritime security is one of the important things that must be created in ASEAN, because this region is dominated by oceans. Indonesia as the largest archipolegic caountry in ASEAN have a role to create maritime security. This paper is to find out how is ASEAN policies in creating maritime security in the ASEAN and to find out what is the role of Indonesia to realizing maritime security in the ASEAN. The method used in this article is the normative method so that this assessment will provide an explanation of Indonesia’s role in realizing maritime security in the ASEAN, either by initiating international forum, or participating in existing maritime international forum, and make regulations for their own country, because Indonesia is one of the counties with largest number of crime at sea in ASEAN.
11C-methionine- and 18F-FDG-PET double-negative metastatic brain tumor from lung adenocarcinoma with paradoxical high 18F-FDG uptake: A case report
Authors: Tanahashi Kuniaki , Hirano Masaki , Chalise Lushun , Tsugawa Takahiko , Okumura Yuka , Hase Tetsunari , Ohka Fumiharu , Motomura Kazuya , Takeuchi Kazuhito , Nagata Yuichi , Nakahara Norimoto , Hashimoto Naozumi , Saito Ryuta
Published: August 2022

Background:

Imaging with 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) and 11C-methionine (MET)-PET can delineate primary and metastatic brain tumors. Lesion size affects the sensitivity of both scans and histopathological features can also influence FDG-PET, but the effects on MET-PET have not been elucidated.

Case Description:

We report an unusual case of metastatic brain tumors without accumulation of FDG or MET, contrasting with high FDG uptake in the primary lung lesion. The brain lesions were identified as adenocarcinoma with a more mucus-rich background, contributing to the indistinct accumulation of both FDG and MET.

Conclusion:

Histopathological characteristics can affect both MET and FDG accumulation, leading to findings contradicting those of the primary lesion.
Case report: Primary ependymoma of the trigeminal nerve presenting as trigeminal neuralgia
Authors: Shah Zara , Islam Mohammad Yousuf , Suleman Fatima , Memon Aisha Hassan , Mubarak Fatima , Shamim Shahzad M.
Published: August 2022

Background:

Ependymomas are usually found in the posterior fossa originating from the fourth ventricle. Primary ependymomas arising from cranial nerves are rare with only a handful of reported cases. Trigeminal neuralgia (TN) is rarely due to space occupying lesions.

Case Description:

A 20-year-old female presented with TN with a rare presentation of a pure extra-axial ependymoma involving the right trigeminal nerve in the cerebellopontine angle.

Conclusion:

It is essential to explore the possibility of a mass arising from the trigeminal nerve when investigating the cause of TN.