bluuebunny/crossref_metadata_2025 huggingface dataset:
The Research on the Relationship between Network, Resources Acquisition and Born Global Company’s Internationalization – Based on Case Studies from China
Authors: Zhang Junjie , Chen Rongyao
Published: November 2016

Based on social network theory and RBV theories, the paper adopts cross case studies research method to analyze how network relationship facilitates born global companies to acquire resources in their internationalization process through three Chinese born global company case studies. The research indicates that born global company’s network relationship built up in internationalization process can be classified into domestic strong ties, domestic weak ties, foreign strong ties and foreign weak ties in line with network ties’ strength and geographic dispersion. Those four types of network ties play very important as well as differentiated roles in Chinese born global companies’ internationalization process.
Effect of Anti Diabetic Drugs on Lipid Profile in Patients with Type 2 Diabetes Mellitus
Authors: Jawad Alaa H. , Al-Qaisi Zyad H. , Ibrahim Ammal E. , Hallab Zainab S. , Graisa Abdualbasit , Al-Amiery Ahmed , Yousif Emad
Published: November 2016

Diabetes mellitus (DM) has been defined as a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. This study includes (84) subjects, their age ranged from (40 to 54) years. (20) subjects were healthy chosen as control group and (64) patients with type 2 diabetes mellitus were divided into three groups according to their type of anti diabetic therapy: (23) newly diagnosed group without therapy (Group1), (20) with metformin therapy (Group2) and (21) with metformin plus glibenclamide therapies (Group3). In the study lipid profile level were quantitatively determine by enzymatic methods, in addition to that fasting plasma glucose (FPG), Glycated hemoglobin (HbA1c%) and body mass index (BMI) were identified in the patients. There is significant increase in the level of lipid profile in patients group. Metformin alone produce a non-significant favorable effect on all lipids profile parameters while metformin plus glibenclamide showed a significant reduction in TC and LDL-C.
Considerable Recovery Effect Of EPL And Ashwagandha On The Weight Of Dams And Foetal Weight In Swiss Albino Mice Due To Intoxication Of Mercuric Chloride
Authors: Tiwari Vishwas
Published: November 2016

Investigations were furnished on the toxic effect of mercuric chloride in foetal weights and weight of dam in mice with remarkable recovery effect of Withania somnifera (Ashwagandha) and Essentiale phospholipids (EPL) were observed. Withania somnifera is popularly known as Indian Ginseng and its withanoid content improves the greater gain in body weight, whereas dilinoleoylphosphatidylcholine content of EPL revealed high affinity with lipid contents of blood which consequently increased adipose tissues of body.

 The animals were treated with 0.5 ppm aqueous mercuric chloride for a period of 7, 14 and 21 days. For the recovery 175 mg of EPL and 35 mg of ashwagandha were administered to mice (already treated with HgCl2) for a period of 7, 14 and 21 days. Daily treatment of HgCl2 for 7, 14 and 21 days decreased weight of foetuses and dams. Simultaneous administration of EPL and ashwagandha significantly recovered the weight of foetuses and dams. It appears that the protective effects of EPL and ashwagandha against HgCl2 induced weight alteration is mediated through antioxidative action of EPL and ashwagandha. 
A Study to Understand the Factors that Play Major Role in Influencing the Loyalty Behaviour of Shoppers towards Department Based Brick-and-Mortar Fashion Retailers with Special Reference to Pune City, India
Authors: Karangutkar Sarita , Chaudhary Prashant , Shah Siddhant
Published: November 2016

The major objective of this study is to understanding the factors that influence the loyalty behaviour of customers towards brick-and-mortar departmental fashion retailers in Pune city. The study has been conducted by keeping one of the leading departmental stores in reference, but the findings of the study are generalized and can be applied to other fashion retailers of similar or non-similar formats. Fashion is one of the fastest growing categories and continues to grow at exponential growth rate due to increased fashion awareness and aspirations. Today we can see that fashion products account for a substantial percentage of the products sold across a broad range of merchandise categories.

Research on fashion retailing has been based on varying conceptual definitions of the construct and has focused primarily on in-store retailing. A number of researchers have made important contributions to understanding of loyalty behaviour of shoppers towards fashion retailers.  Therefore, the consumer behaviour of an important sector of the millennials is worth to be researched. Here the researchers are trying to understand the variables that influence shoppers' loyalty behaviour which is nothing but the “preferential” behaviour of the shoppers towards a specific retailer’s stores. During this research the researchers found that, some of the major influencing factors are shopping atmosphere-ambience, fashion image of the retailer (retailer as a brand), fashion image of the Private Labels, and the effectiveness of the loyalty programme offered by the retailer.
Analysis of Employment of Women Salaries in Family and its Impact on the Status of Family of Kota City
Authors: Maheshwari Meenu , Sodani Priya
Published: November 2016

This paper seeks to analyse the relationship between the women’s opinion for the extent of employment of their income in different heads of family and its overall effect on family status of Kota city. This analysis of women participants’ opinion of Kota city for the factors of family which are nourished by their income are Financial Position and Status, Societal Status and Position, Living Standard and Statue, Education of Children, Family and Personal Health Security, Quality of life and Risk taking capabilities. Distribution of women participants’ opinion for application of their salaries in different expenditure heads of family are: in constructing home, in buying cars and automobiles, in education fees, in Insurance / Family Security, in Recreation and Leisure time, in Saving and Deposits / Investments, in Routine Expenses, in Medical and Health Issues, and in Paying Taxes. Their opinion might be influenced by the age group, educational qualification and current sector of their job. It has been an empirical study involving a questionnaire collected from 450 working women respondents working in Kota city, Rajasthan. A deep analysis of the findings will be discussed in this paper.
Self-Help Group of Rural Assam and Its Role in Women Empowerment
Authors: Saikia Polee
Published: November 2016

Women empowerment is a universal issue. Women empowerment refers to the creation of an environment for women where they can make decisions of their own for their personal benefits as well as for the society. It refers to increasing and improving the social, economic, political and legal strength of the women, to ensure equal right to women and to make them confident enough to claim their rights. The overall development of the nation remains as a paradox until and unless the women got empowered. The under privileged rural women are still far from empowerment. Unemployment, illiteracy and low social recognition made them so. Presently the self-help groups that mushrooming in different corners of rural Assam have been creating opportunities for women to be empowered. Here in this study an attempt has been made to study whether the rural women got scope to get empowered by getting engagement in self-help groups. 40 women from 04 self-help groups, 13 literate and 27 illiterate women were taken as sample for the study. To collect first hand data self structured questionnaire and self structured interview schedule were prepared by the investigators. Percentage was used to analyze data.
Contribution of SHRM towards Organizational Effectiveness- A Study with Reference to NGOs in Kerala
Authors: Mathew Anu P
Published: November 2016

As the business environment has become more and more complex and uncertain over the years, it becomes imperative for organizations to adopt strategies and effectively putting them into practice so that they can attain solid competitive advantage in the fiercely competitive market. Human resources very well play a significant part in realization of organizational goals in the most effective manner. Effective alignment of firm’s strategies with the individual ones is the end result of successful Strategic Human Resource Management. This is even more relevant with NGOs as their vital resource is not material or infrastructure oriented but rather human oriented. The more is the linkage between HRM and organizational performance through strategic means the greater will be the organizational outcome. Through this research paper, a study is being made to understand how significantly related is SHRM and organizational effectiveness. Data collected through primary and secondary sources validate a highly positive relationship between the both.
The University–Public Health Partnership for Public Health Research Training in Quebec, Canada
Authors: Paradis Gilles , Hamelin Anne-Marie , Malowany Maureen , Levy Joseph , Rossignol Michel , Bergeron Pierre , Kishchuk Natalie
Published: November 2016

Enhancing effective preventive interventions to address contemporary public health problems requires improved capacity for applied public health research. A particular need has been recognized for capacity development in population health intervention research to address the complex multidisciplinary challenges of developing, implementing, and evaluating public health practices, intervention programs, and policies. Research training programs need to adapt to these new realities.

We have presented an example of a 2003 to 2015 training program in transdisciplinary research on public health interventions that embedded doctoral and postdoctoral trainees in public health organizations in Quebec, Canada.

This university–public health partnership for research training is an example of how to link science and practice to meet emerging needs in public health.
Episodic Rainwater Movement in a Hydrophobic Sparta Sand under Three Ecosystems in Lower Wisconsin River Valley
Authors: Flores-Mangual Mario L. , Lowery Birl , Bockheim James G.
Published: November 2016

Core Ideas

Prairie to pine conversion reduced soil water and drainage because of hydrophobicity and interception.

Soil‐applied surfactant did not increase soil water content or water drainage.

Early afforested prairie had similar soil water content and drainage to natural prairie.

Early afforested prairie had greater soil water content and drainage than pine plantation.

Vegetation can directly affect soil water dynamics through rainfall interception and evapotranspiration. Vegetation type probably is one factor that causes soil hydrophobicity, and hydrophobicity can influence water infiltration and groundwater recharge. Surfactants can be used to alleviate non‐wetting conditions. The objectives of this study were to determine the effects of vegetation type on soil water content and groundwater recharge and to explore if a soil‐applied surfactant can increase both conditions. The research was located in the Lower Wisconsin River Valley (LWRV), on Sparta sand with three different vegetation ecosystems: prairie, pine plantation, and mixed prairie and forest (mixed vegetation); hydrophobicity has been found to be pronounced under pine plantations in the LWRV. Soil water content was monitored at three depths (5, 25, and 70 cm) with time domain reflectometry. Groundwater recharge was assessed by monitoring wells equipped with pressure transducers. Rain gauges and weather stations were installed to measure precipitation and air temperature. Soil core samples were collected for tests of saturated hydraulic conductivity (Ks) and bulk density (Db). Surfactant was applied on half of the plots after collecting several years of background data. There was significantly less soil water under the pine plantation than the prairie and mixed vegetation. Groundwater recharge did not vary among vegetation types, probably because differences were obliterated due to high aquifer transmissivity. The pine plantation had less profile drainage; however, the surfactant did not increase profile drainage. There were no differences in Ks and Db. The conversion from prairie to pine plantation resulted in reduced soil water content and drainage.
Knowledge towards breast cancer among Libyan women in Tripoli
Authors: Taher Y A , Samud A M , Benhusein G M
Published: November 2016

Introduction: Breast cancer in women is the commonest type of cancer worldwide. However, in Libya, ordinary systematic screening for breast cancer is neglected.

Aim: The present study was aimed to evaluate the women's knowledge towards breast cancer and its risk factors.

Methods: A cross-sectional survey, using self-administered questionnaire and face-to-face interviews was conducted at different places in Tripoli city along a period of nine months, from April-December 2013.

Results: The mean age (±bSD) of the participating women was 48±b5 years and out of 284 contributors 84.5% were married. One hundred and eighty women (63.4%) stated that long-term use of contraceptive pills (> 5 years) increases the incidence rate of breast cancer. Besides, more than half of participants (157 women) specified that breast cancer is treated by surgery, chemotherapy and radiotherapy. However, although 50.7% of women reported that mammography and ultrasound are used for early detection, more than 60% of women believed that mammogram can cause cancer. In addition, our data demonstrate that increased knowledge was associated with women who know how to do self-examination and living in urban area.

Conclusion: Our findings demonstrate that Libyan women have acceptable level of knowledge regarding breast cancer. However, improvement of the health systems and awareness regarding breast cancer is needed.
Alternativa de protección contra la corrosión del acero AISI 310S mediante recubrimiento de aluminio bajo condiciones de platos separadores en celdas de combustible de carbonatos fundidos
Authors: Orozco-Cruz Ricardo , Mejía-Sánchez E. , Galván-Martínez R.
Published: November 2016

Introducción: La celda de combustible de carbonatos fundidos (MCFC, por sus siglas en inglés) convencional opera a 650°C. Consiste de un cátodo de NiO poroso y litiado, una mezcla eutéctica de carbonato de litio (Li2CO3) y carbonato de potasio (K2CO3) fundido en una matriz electrolitica de óxido de aluminio litiado (LiAlO2) y un ánodo poroso de Ni. Los platos separadores entre cada celda presentan problemas de corrosión. Ante eso, un acero inoxidable AISI 310S con recubrimiento fue estudiado en condiciones de un plato separador en una MCFC.Método:  Se utilizó un acero inoxidable AISI 310S como sustrato (muestra A), aplicándole un recubrimiento de Al con (B) y sin tratamiento térmico (C). Fueron expuestos en carbonatos fundidos (62 mol% Li2CO3 -38 mol% K2CO3) a 650 °C en crisoles de alúmina. El comportamiento electroquímico fue estudiado mediante la técnica de Espectroscopía de Impedancia Electroquimica (EIS). Para el análisis de los diagramas de impedancia, se utilizó el software de simulación “Boukamp Equivalent Circuit”. La sección transversal de las muestras corroídas fue caracterizada mediante Microscopía Electrónica de Barrido (SEM, por sus siglas en inglés)) y los productos formados por Difracción de rayos X (XRD, por sus siglas en inglés)).Resultados: Los diagramas de EIS presentan aumentos y disminuciones en los semicírculos formados a altas frecuencias indicativo de disolución de la capa externa, aumento y disminución de la resistencia de esta última así como el posible rompimiento de ella. La técnica de XRD presentó fases LiFeO2, LiCrO2, g-LiAlO2 y a-LiAlO2 así como fases intermetálicas para las distintas condiciones de la muestra. De la misma manera, los análisis de SEM presentaron los espesores de cada una de las capas formadas.Discusión o Conclusión: En la muestra A, se formaron capas de LiFeO2 y LiCrO2 después de 200 horas de exposición. La capa de LiCrO2 aumenta por la difusión de Li hacia el interior y de Cr hacia el exterior. En la muestra B y C, se ha encontrado la fase LiAlO2 presente en la capa externa. En la muestra B, esta capa de LiAlO2 es muy delgada y además no homogénea y esto indica lo susceptible que puede ser al medio, y la capa que se ha formado en la muestra C ha sido de mayor espesor. El efecto del tratamiento térmico, cuyo objetivo es la difusión del Al hacia el interior, ha sido aceptable. La aplicación del recubrimiento es una alternativa para extender la vida útil de estos materiales.
Prediction of the permeability-reducing effect of cement infiltration into sandy soils
Authors: Ji Jinlan , Fan Guisheng
Published: November 2016

Univariate analysis on the permeability-reducing effects of cement infiltration into sandy soil was carried out using a series of experiments on sandy soil infiltrated by adding fine cement grains. The SPSS statistical analysis software was used on these experimental data to construct multivariate prediction models on the permeability-reducing effects of cement infiltration into sandy soils. The results indicate that it is possible to predict permeability-reducing effects using transfer functions. Relatively satisfactory predictions were achieved by inputting the postponed time of water supply, soil dry density, quantity of added cement, water pressure head of cement infiltration, physical clay-silt particle content of soil, and other factors as independent variables. A comparison between the multivariate linear and non-linear models showed that the two models had similar accuracy. The multivariate linear model is relatively simple, and hence can be used to predict permeability-reducing effects. The development of the models has scientific implications for soil modification by altering soil permeability through cement infiltration. It also has practical significance in predictive research on reducing the migration of ground surface pollutants into groundwater.
Enhancement of struvite pellets crystallization in a full-scale plant using an industrial grade magnesium product
Authors: Crutchik D. , Morales N. , Vázquez-Padín J. R. , Garrido J. M.
Published: November 2016

A full-scale struvite crystallization system was operated for the treatment of the centrate obtained from the sludge anaerobic digester in a municipal wastewater treatment plant. Additionally, the feasibility of an industrial grade Mg(OH)2 as a cheap magnesium and alkali source was also investigated. The struvite crystallization plant was operated for two different periods: period I, in which an influent with low phosphate concentration (34.0 mg P·L−1) was fed to the crystallization plant; and period II, in which an influent with higher phosphate concentration (68.0 mg P·L−1) was used. A high efficiency of phosphorus recovery by struvite crystallization was obtained, even when the effluent treated had a high level of alkalinity. Phosphorus recovery percentage was around 77%, with a phosphate concentration in the effluent between 10.0 and 30.0 mg P·L−1. The experiments gained struvite pellets of 0.5–5.0 mm size. Moreover, the consumption of Mg(OH)2 was estimated at 1.5 mol Mg added·mol P recovered−1. Thus, industrial grade Mg(OH)2 can be an economical alternative as magnesium and alkali sources for struvite crystallization at industrial scale.
Pulmonary Hypertension Patient Navigation: Avoiding the Perfect Storm
Authors: Jones Sharon
Published: November 2016

Pulmonary arterial hypertension (PAH) is a progressive, incurable disease that presents a challenging journey for all involved. Specialized, complex care and treatment is needed for this population of patients, and should be provided in an organized, systematic manner to promote optimal patient outcomes. The concept of patient navigation can be used as a framework for the pulmonary hypertension (PH) center, so that care delivery is well structured and PAH patients have a guide to assist them through all aspects of the health care continuum. This article will focus on how a PH patient navigation program can be implemented and the role of a PH nurse navigator, using the Christiana Care Health System Pulmonary Hypertension Program in Newark, Delaware, as an example. There have been many advances in PAH diagnosis and treatment in the last 20 years, and the time has come to introduce a PH patient navigation model that can be used as a guide to structure PH programs.
Clinical efficacy of Kapha Ketu Rasa on Tamaka Swasa
Authors: Anuroopa H K  , Shankar Gouda  , Madhava Diggavi
Published: November 2016

Context: Compound drugs are scientifically formulated aiming to get the desired therapeutic effects through synergy. Kapha Ketu Rasa is one such compound drug which is a classical herbo mineral marine Khalvi Rasayana judicially containing Shankha Bhasma, Vatsanabha, Tankana and Pippali. Treating GERD along with the treatment of bronchial asthma will enhance the clinical success rate. At this juncture, it is worth to notice the pharmacology of Kapha Ketu Rasa in the same perspective. Aims: To study the clinical effect of Kapha Ketu Rasa on Tamaka Swasa (Bronchial asthma). Materials and Methods: 30 Patients of Tamaka Swasa irrespective of age, sex, religion etc., were randomly selected and treated with 125 mg of Kapha Ketu Rasa capsules twice a day with Ardraka Swarasa before meals for 21 days, then followed for 21 more days. Results: The clinical study showed statistically highly significant improvement in both subjective and objective parameters viz. Kasa (91%), Ghurghurata (83%) and Swasakruchrata (82%) including decrease in AEC, ESR, Differential eosinophil count and PEF was also statistically significantly improved. Conclusions: Kapha Ketu Rasa is an effective Vyadhi Pratyanika herbo mineral Shamana Rasayana in the management of Tamaka Swasa.
Clinical study on the Rasayana effect of Ashwaganda and Punarnava
Authors: Vijay B. Negalur
Published: November 2016

Background: It has been the desire of mankind to lead a disease free life to its fullest extent. To improve quality and quantum of life ‘Rasayana’ has been explained in Ayurveda. It is not only indicated in the diseased but also in healthy individuals. Ashwagandha (Withania somnifera Dunal) and Punarnava (Boerhavia diffusa Linn) are explained by Vagbhata in Rasayana context. Both these can be administered without much restrictions as per Vatatapika mode of administration. Objectives: To study the Rasayana effect of Ashwagandha and Punaranava w.r.s. Ajasrika Rasayana. Materials and Methods: 32 students who fulfill the inclusion criteria were selected from S.D.M. College of Ayurveda, Hassan. They were divided in to two groups. Group A – 16 members were given with 2 tablets of Harithaki for 3 days for ‘Koshta Shudhi’, followed by a placebo with warm water before taking food for 40 days and kept as control. Group B – 16 members were given with 2 tablets of Haritaki tablets for ‘Koshta Shudhi’ followed by administration of 12 gm of Ashwagandha and Punarnava granules (equal quantity) twice a day along with warm water before taking food for 40 days. Results: Assessment was done two times in 40 days before and after the administration of Ashwapunarnava compound and were assessed for improvement in terms of subjective and objective parameters. Observations and results were tabulated and statistically analyzed with relevant parameters. Conclusion: Ashwapunarnava compound proved to be cost effective, palatable, safe and better drug for daily administration without much restriction.
Survey study on interrelationship of way of life and etiopathogenesis of Prameha
Authors: Mohan Krishna Dwivedi  , Dhoke SP  , Galib  , Prajapati PK
Published: November 2016

Introduction: In 21st century, non-communicable diseases are prone to kill more people which are the result of changing Lifestyle, includes unhealthy dietary habits and malfeasance behavioural pattern. In Ayurveda, Ahara Vidhi (Dietary rules), Vihara (Conducts) etc. are described in detail which can be included under the heading Lifestyle in which Prameha is one of them. Aims: To establish the relationship between disturbances in lifestyle and manifestation of disease Prameha. Settings and Design: Cross sectional Survey Study. Materials and Methods: Survey study was carried out on 72 diagnosed patients of Prameha with disturbed lifestyle which shows that disturbances in Lifestyle such as irregular food habits, irregular sleep pattern affects the balances of Doshas and further Kosthaa and Agni. Results: Meda and Mutra Vriddhi leads to Medovaha Srotas Dushti and by lack of Hygiene the Svedavaha Sroto Dushti occurs. Hence finally get affected with Apathyanimmitaja-Prameha. Conclusions: Most of the lifestyle and dietary pattern in today’s era belongs to Parthiva and Jala Mahabhuta dominance. Hence by avoiding these type of dietary pattern and life style someone escapes these type of life style disease.
Phamacognostical and Pharmaceutical Evaluation of Chandrashakaladi Vataka - A herbal formulation
Authors: Akash S Changole  , Mandip Goyal  , Harisha CR
Published: November 2016

Background: Quality control and the standardization of herbal medicines involve steps like standard source and quality of raw materials, good manufacturing practices and adequate analytical screening. These practices play a vital role in guaranting the quality and stability of herbal preparations. Chandrashakaladi Vataka is an Ayurvedic herbal formulation mentioned to be beneficial in Kushtha. Till date no published data is available on its analytical profile. Aim: To develop the Pharmacognostical and Phyto-chemical profile of Chandrashakaladi Vataka. Material and Methods: Chandrashakaladi Vataka was prepared as per classical method and analytical findings were recorded. Samples were subjected to organoleptic analysis, physico-chemical analysis and HPTLC examination by optimizing the solvent systems. Results and Conclusions: Pharmacognostical profile of Chandrashakaladi Vataka was established. Loss on drying, Ash value, Acid insoluble extract, Methanol soluble extract, Chandrashakaladi Vataka was found within prescribed limits. HPTLC profile of Chandrashakaladi Vataka revealed 12 spots at 254 nm and 13 spots at 366 nm.
Pharmaceutical Standardization of Saptamrita Lauha
Authors: Pranav K. Shah  , L. B. Singh  , P.U. Vaishnav  , Bharat Kalsariya
Published: November 2016

Shalakya Tantra is a one of the branch of Ashtanga Ayurveda and Netra Chikitsa is a part of Shalakya Tantra. There are so many formulations are mentioned in the treatment of Netra Roga by oral route as well as external application, Saptamrita Lauha is one of them. It is a very popular, very safe and effective formulation for eye diseases. In Ayurveda classics there are so many references are available for Saptamrita Lauha. These formulation are mainly described in Netra Roga and Shoola Roga in almost all the books. In majority references Saptamrita Lauha powder is taken with Anupana or Sahapana of honey and ghee. Sundar Ayurveda Teaching Pharmacy is also manufacturing many batches of Saptamrita Lauha with the reference from Bheshaja Samhita, chapter 4/54, Loha and Mandura Kalpana and follow the in house quality control parameters to standardized the medicine in large scale production. The particle size of Saptamrita Lauha is 3.2 µm to 3.8 µm, pH from 6.0 to 6.9, loss on drying from 1.2 % to 1.8%, ash value 16.2 %w/w to 24.5 %w/w, acid insoluble ash value from 2.6 %w/w to3.6 %w/w, alcohol soluble extractive value from 42.9% v/w to 47.7 %v/w, water soluble extractive value from 21.1 % to 26.8%. Phyto-chemical screening of Saptamrita Lauha shows Glycoside, Amino acid, Protein, Carbohydrate, Flavanoid, Tannin, Steroid, Saponin and Alkaloid were present in all batches. On the basis of this study it’s clear that, if we follow the same procedure with authentic drugs then large scale production also having Quality assurance.
The study of Satwa Sarata with special reference to Emotional Maturity
Authors: Amit Nakhanekar  , Gaikwad Balasaheb D
Published: November 2016

Sarata or excellence is described with respect to Satwa (mind). Sarata is quality assessment of Sapta Dhatu and Satwa. Examination of Sarata is done at physical and psychological level. The present study aims at assessing Satwa Sarata and emotional maturity. The participants of the study were included 60 subjects between age group of 20 to 40 years. A proforma, specially designed on the basis of classical descriptions of Satwa Sara was utilized to assess the Sarata. Findings of the study revealed that the association in Satwa Sarata and emotional maturity was statistically highly significant (p<0.001).
Significance of Deepana and Pachana activity in the treatment of Amapradoshaja Vikaras
Authors: Ashok Kumar BN  , Abhishek  , Shruthi CS.
Published: November 2016

Agni plays an important role in digestion of food. All the diseases are produced by Mandagni. Mandagni leads to the formation of Ama which is the root cause of Roga Utpatti. There are so many diseases originating beacause of Ama which are grouped under Ampradoshaja Vikara. Deepana and Pachana are considered under the heading of Shamanaushadhis. It is the first line of treatment selected in order to overcome Ampradoshaja Vikaras. They are very successfully utilised for the day to day practice.There are different views given by our Acharyas regarding Agni, Ama, Amaja Vikaras and role of Deepana and Pachana in their management which are highlighted in this article.
Madhura Triphala – A Review
Authors: Dhulappa M
Published: November 2016

The concept of Triphala in the literature of Ayurveda is famous. With the term Triphala we should take Haritaki, Bibhitaki and Amalak into consideration. But Acharya Pandit Narahari in his text Raj Nighantu mentioned another group of dravya named Madhura Triphala (sweet three fruits), such as Draksha, Kashmarya and Kharjura. These are also called as Madhuradi Triphala, because they are predominated by Madhura Rasa (sweet taste). This group is predominated by Madhura Rasa (sweet taste), Sheeta Veerya (cold in potency) and Madhura Vipaka (undergoes sweet metabolic changes) and it will act as Balya (strengthening), Brahmaneeya (nourishing), Rasayana (rejuvenator), Vajeekarana (aphrodisiac). Hence it may used as food supplement along with medicine in the management of diseases.
A Life Style Disorder - Hypertension
Authors: Jambla Neha  , Saroch Vikas  , Kundailia Neetika
Published: November 2016

Life style diseases are also called as the diseases of longevity or diseases of civilization. Once bacteria and virus were the prime killers in human society. But, now the studies shows that 17 million people die prematurely each year as a result of the global epidemic of largely preventable diseases or life style diseases which proves that we humans only are the killers of ourselves. Today more than 5 of 10 biggest killing diseases are caused by carelessness, ignorance and irregularities of our own. According to WHO, world deaths from life style diseases will double by 2015 unless all out efforts are taken to combat them. So it is mandatory to develop a health oriented life style than to give deep concern about our works. The scope almost fully lies on Ayurvedic concepts, because of its references of preventive measures. A report jointly prepared by the World Health Orientation and the World Economic Forum says India will incur an accumulated loss of $236.6 billion by 2015 on account of unhealthy life styles and faulty diet. As we all know, hypertension is called a silent killer, because it rarely exhibits symptoms before it damages the heart, brain or kidney. Hypertension is an important worldwide public health challenge and remains a major cause of morbidity and mortality worldwide.
Relavance of Garbhotpattikar Shadbhav in genesis of foetus
Authors: Smita Jha  , Sachin G. Khedikar
Published: November 2016

Genetics is the science that deals with transmission of biological properties from parents to offspring. It crisscross with life science and linked with modern embryology. In Ayurveda certain factors are described in view of genesis of embryo or foetus. Acharyas had described Ashtaprakriti, Shodashvikara and Atma in the formation of Garbh. While describing detailed embryology Acharyas have described about Matrijadi Garbhotpattikar Shadbhav. These are factors described for the development of foetus. As Ayurveda is based on eternal and concealed facts. Modern embryology is much advance in this field. Development of embryois is well defined. Whatever the features and development of different parts of foetus described with assistance of the 6 factors may be helpfull to enhance the goal of Ayurveda embryology, that is Suprajanan.
Rationality of pharmaceutical preparations in Ayurveda
Authors: Benoy Bhaskaran
Published: November 2016

Pharmaceutical preparations are meant for easy application of drugs and also to ensure ready and harmless usage. Preparations in Ayurveda are primary and secondary. Primary preparations are aqueous preparations whereas secondary preparations are various types of fermented medications, oil and fat medicated preparations. Multi medicated drugs (Avarthi) are in other angle. Semi solid sweetened preparations like Avaleha provides with natural preservation and palatability for the medicinal ingredients. Preparations from metals and minerals like Bhasma and Sindhura, highly potentiated with reduced bulk are also in another angle with a wide spectrum of usage.
Conceptual study of Dooshivisha (Cumulative toxicity) w.r.t. Ancient classics and Modern science
Authors: Pradeep Patil  , Patil KS  , Hande Sudarshan  , Pawar Vinay  , Mujumdar Amit  , Mhatre Ashish
Published: November 2016

Ayurveda describes the vast turnover of beauty aid products. More and more new synthetic substances are introduced every day. Many of these are not adequately tested for safety, in particular for routes other than oral or parenteral. Increased incidence of skin conditions like eczema and contact dermatitis after using newer cosmetics suggest that this may be due to local toxic effects or toxic effects manifested on this phenomenon as Dooshivisha. They are relevant to the current way of life considering the prevalence of pollution, occupational hazards and extent of exposure to toxins in food and other articles used in daily life. Present generation is much more likely to consume junk foods-cold drinks, to have unhealthy travelling habits, working late nights, working with computers in A.C rooms. This is referred to by terms like Hetusatatya, Vegavarodha, Diwaswapa, Viparit Chesta, Virudhannasevana which in turn hamper the normal physiology of human body. Same thing is mentioned in Ayurvedic texts also under the topic of Pradnyaparadh which is the basic cause for all diseases. This Pradnyaparadha is responsible to disturb the daily routine life and person has to face with the complaints of ill-health.
A Pinch of Salt - Its effect on health
Authors: Komal Vilas Gawali  , Mahesh Vyas  , H.A.Vyas
Published: November 2016

Ayurveda is an ancient science having its roots in Vedic literature which describes certain rules and regulations as a way of living. Over the ages with the advancement of technology, there have been tremendous changes in the lifestyle patterns of the individuals. The Principles of Ayurveda science are the same but it is imperative to match up and draw an analogy with the modern evidences and discover the innovation in them. Gramya Aahara is one such type of diet that is prevalent in the society and is the cause of various diseases. Ati Lavana (excessive consumption of salt) is one of the components mentioned in it. The challenge lies in understanding the dogmas of Ayurveda science thoroughly and also to implement them in this modern era. The harmful effects of salt are propounded by the Ayurveda classics as well as the modern science. This is an attempt to discuss about the excessive consumption of salt from the Ayurveda as well as modern view. This will provide succor in adopting the right manner of consumption of salt pertaining to the requirements of the body.
Вплив вітаміну D на показники компенсації цукрового діабету 2-го типу
Authors: Pasyechko N.V. , Naumova L.V. , Kulchinska V.M. , Gulko N. Ya. , Dzhula M.A. , Krytskyy T.I.
Published: November 2016

Актуальність. Цукровий діабет (ЦД) призводить до порушення всіх видів обміну речовин (насамперед вуглеводного), ураження судин, нервів, різних органів і тканин. Проте вплив ЦД на рівень вітамінів та мікроелементів залишається недостатньо висвітленим. Попри достатній арсенал лікарських середників, досягти компенсації ЦД вдається менше ніж у 30 % пацієнтів. Саме тому пошук нових шляхів покращення вуглеводного обміну залишається актуальним. Мета дослідження: виявлення дефіциту 25-гідроксивітаміну D та встановлення його кореляційного зв’язку з рівнем глікованого гемоглобіну (HbA1c) у хворих на ЦД 2-го типу. Матеріали та методи. Обстежено 35 хворих на ЦД 2-го типу віком 55–74 роки з тривалістю захворювання від двох до чотирьох років. Контрольну групу становили 35 практично здорових осіб такого ж віку. Показники 25-гідроксивітаміну D вимірювали за допомогою радіоімунологічного аналізу. Рівень HbA1c вимірювали за допомогою рідинної хроматографії. Результати. У 37,1 % хворих на ЦД 2-го типу виявлено недостатність вітаміну D. При цьому в 61,5 % з них компенсація ЦД була задовільною (рівень HbA1с становив 7,5–8,5 %), а в 38,5 % — незадовільною (рівень HbA1с > 8,5 %). Встановлено обернену кореляцію між підвищенням рівня HbA1с та зниженням вмісту 25(OH)D (r = –0,39, p < 0,05). Висновки. Встановлено вірогідне покращання стану компенсації цукрового діабету 2-го типу після медикаментозної корекції рівня вітаміну D.
Корекція гіпокальціємії при різних захворюваннях щитоподібної залози після тиреоїдектомії
Authors: Kashperska V.Ya.
Published: November 2016

Попри значні успіхи в розвитку хірургічного лікування захворювань щитоподібної залози (ЩЗ), так і залишаються актуальними і поки невирішеними питання профілактики і корекції післяопераційного гіпопаратиреозу з розробкою чітких рекомендацій для підбору оптимальних схем корекції післяопераційної гіпокальціємії. Мета дослідження: розробити диференційовану схему лікування післяопераційного гіпопаратиреозу і визначити оптимальну терапію гіпокальціємії після тиреоїдектомії при різних захворюваннях ЩЗ. Матеріали і методи. У проспективному дослідженні 77 пацієнтів після тиреоїдектомії з приводу різних захворювань ЩЗ проводилося спостереження впродовж 6 місяців із регулярною оцінкою показників фосфорно-кальцієвого обміну. Відповідно до схеми терапії пацієнти були розподілені на три групи залежно від початкових показників 25(ОН)D до операції і рівня паратгормона після операції. Результати. Оптимальною схемою корекції післяопераційної гіпокальціємії є комбіноване призначення препарату кальцію і аналогів активного метаболіту вітаміну D, що забезпечує швидку позитивну динаміку основних показників фосфорно-кальцієвого обміну із досягненням стійкого ефекту. Усім пацієнтам із захворюванням ЩЗ в період передопераційної підготовки рекомендується проводити визначення 25(ОН)D з метою використання цього показника як прогностичного чинника розвитку післяопераційної гіпокальціємії. Висновки. При виявленні гіпокальціємії після тиреоїдектомії рекомендується розпочати комбіновану терапію препаратами кальцію і аналогами активного метаболіту вітаміну D незалежно від нозології патології щитоподібної залози, об’єму операції, однак слід здійснювати індивідуальний підбір дозування під контролем основних показників фосфорно-кальцієвого обміну.
Взаємозв’язки гормональних порушень і компонентів метаболічного синдрому у хворих на первинний гіпотиреоз
Authors: Yuzvenko Т.Yu.
Published: November 2016

Упродовж останнього десятиліття опублікована велика кількість результатів досліджень, присвячених проблемі гіпотиреозу, що докорінно змінили погляди на значення патології щитоподібної залози загалом. Нейрогуморальні зміни розглядають як патогенетичний чинник розвитку гіпотиреозу в осіб із метаболічним синдромом (МС). Мета дослідження — дослідити особливості гормональних порушень та їх кореляційні взаємозв’язки з компонентами метаболічного синдрому у хворих на первинний гіпотиреоз. Матеріали та методи. Обстежено 80 хворих на первинний гіпотиреоз, серед них у 61 особи відмічався МС, у 19 ознак МС не спостерігалося. Результати. Хворим на гіпотиреоз із МС притаманна гіперлептинемія в поєднанні з гіперінсулінемією, гіперкортизолемією, підвищенням рівня С-пептиду, при цьому найсуттєвіші зміни спостерігаються у хворих із повним (багатокомпонентним) МС. Висновки. Установлено взаємозв’язки гіперлептинемії із вмістом глікемії натще, глікованим гемоглобіном, рівнем інсуліну, тиреотропного гормона, індексом HOMA, що свідчить про модулюючу роль хронічної гіперглікемії, гормональних порушень та інсулінорезистентності до експресії та реалізації біологічної дії лептину у хворих на гіпотиреоз із МС.
Сучасні погляди на алгоритми ведення вагітних і породіль із дифузним токсичним зобом
Authors: Pankiv V.I. , Payenok O.S. , Kostiv M.O.
Published: November 2016

У статті наведені сучасні погляди та дані щодо чинників ризику, механізмів розвитку, клінічних особливостей та ускладнень дифузного токсичного зоба під час вагітності, пологів, у післяпологовому періоді та у новонароджених. Висвітлена інформація щодо сучасних підходів до діагностики, лікування та профілактики цього захворювання, що надає підставу рекомендувати її для впровадження в практику.
The Diversity of Legume-Nodulating Bacteria from Several Agroecosystems in Sumberjaya, Lampung
Authors: Wedhastri Sri , Prahastiwi Yuliana , Widada Jaka , Widianto Donny , Kabirun Siti
Published: November 2016

Bacteria that capable of forming root nodules on legumes are known as Rhizobia. They have also known as Legume- Nodulating Bacteria (LNB). They can fi x nitrogen from the atmosphere. Diversity of Legume-Nodulating Bacteria is affected by biotic factors (such as their genetic factors, plants, and competition with the other soil microbes) and abiotic factors (such as land use, soil’s temperature, pH, chemistry and soil’s properties). The aim of this experiment is to know the diversity of eleven Legume- Nodulating Bacteria based on their phenotypic and genotypic characters. The eleven LNB used in this experiments were isolated from several agroecosystems in Sumberjaya, Lampung. The analysis of these LNB diversity were carried out by characterizing both phenotypic and genotypic properties. The diversity analysis showed that the eleven LNB isolates had high diversity, based on nodule formation, and classifi ed into two groups of cross inoculation group. Key words: Rhizobia, phenotypic diversity, genotypic diversity
Agrobacterium-Mediated Stable Transformation of Medicinal Plant Andrographis paniculata Callus Expressing β-glucuronidase (GUS) Gene
Authors: Marwani Erly , Tangapo Agustina , Dwivany Fenny Martha
Published: November 2016

This study was carried out to establish a stable genetic transformation in callus culture of Andrographispaniculata mediated by Agrobacterium tumefaciens. The leaf disks of A. paniculata were infected with A. tumefaciensLBA4404 carrying a binary vector pCAMBIA1304 that contain β-glucuronidase (GUS) and hygromycinphosphotransferase (hpt) genes. The infection was conducted by dipping method for one hour, followed byco-cultivation in the dark for three days. To examine transient GUS expression, the co-cultivated leaf disks wereassayed for β-glucuronidase activity and to obtain stable transformed callus, the co-cultivated leaf disks wereselected on the callus induction medium which contain 20 mg/l hygromycin for selection. The transformedcallus was periodically subcultured every three weeks into the fresh selection medium over the 15 weeksperiod. To test a stable transformation, the callus was subjected to PCR analysis for GUS gene detection. Theresults indicated that the co-cultivated leaf disks expressed GUS activity and proliferated to produce callus onthe selective medium. Analysis of PCR on the transformed callus indicated the presence 976 bp fragment thatconfi rmed the presence of β-glucuronidase gene. These fi ndings imply that the β-glucuronidase was stably integrated into A. paniculata callus culture.Keywords: Andrographis paniculata, Agrobacterium tumefaciens, andrographollide, transformed callus,β-glucuronidase gene.
Cytotoxicity of Buah Merah (Pandanus conoideus Lamk.) Extract on Breast Cancer Cell Line (T47D)
Authors: Nuringtyas Tri R. , Pratama Yoga , Galih G. , Wahyuono Subagus , Moeljopawiro Sukarti
Published: November 2016

Buah Merah (Pandanus conoideus Lamk.) has been extensively used to treat various diseases includingcancer. There are many varieties of buah merah and there was no scientifi c study comparing cytotoxicity ofdifferent varieties. The objective of this study was to investigate the cytotoxicity of three varieties of buah merahknown as Barugum, Maler and Yanggiru on breast cancer cell line (T47D). All samples were collected fromPapua, Indonesia. Each sample was extracted consecutively using three solvents chloroform, methanol andwater resulted to nine crude extracts. The cytotoxic activities were determined using MTT assay. The crudeextract showed the lowest IC50 was selected for further bioassay-guided fractionation. Fractionation was doneusing vacuum liquid chromatography coupled with preparative TLC to fi nd the active compounds. Severaldetection reagents were applied to TLC for identifi cation of the class of the potent compounds. The resultshowed that the potent extracts was obtained from Barugum methanol extract followed by Maler chloroformextract with IC50 value of 132.83 μg/ml and 139.72 μg/ml, respectively. All Yanggiru extracts did not showactivity. The bioassay-guided fractionation of Barugum and Maler extracts showed that the most potent fractioneluted by a mixture of hexane:ethyl acetate (75:25), was in Maler variety with IC50 value of 25,7 μg/ml, fourtimes higher than the most potent fraction of Barugum with IC50 value of 104,61 μg/ml. TLC analysis of themost potent fraction showed that the active compounds was class of terpene. Result of this study supportedthe utilization of buah merah Maler variety for breast cancer treatment.
Genetic Determination and Clonal Relationships of Staphylococcus aureus Isolated from Dairy Cows in Baturraden, Central Java, Indonesia
Authors: Aziz Fatkhanuddin , Salasia Siti Isrina Oktavia , Slipranata Mitra
Published: November 2016

Cases of mastitis in cows at Baturraden are leading to signifi cant and ongoing problems due to reducedproduction and lower milk quality. This study was designed to identify which of selected virulence determinantgenes of S. aureus are involved in the Baturraden infection, and to determine the clonal relationship amongthese isolates. Seventeen isolates were identifi ed as S. aureus based on their biochemical properties and speciesspecifi city for 23S rRNA and nuc genes. S. aureus isolates were genotypically characterized for the selectedvirulence determinants: coa, clfA, fnbA, fnbB, cap5, spa IgG and spa X- region genes. Clonal relationship analysisamong isolates was carried out using AFLP and results compared with previously confi rmed relationshipsbetween selected S. aureus isolated from other regions. The results show that eight isolates contain all thegenes, but six isolates lack fnbB and two isolates lack cap5 genes. AFLP analysis showed that all isolates of S.aureus originating from cows in Baturraden belong to one cluster. This study provides additional knowledgeabout S. aureus infection in Baturraden cows, including the number of virulence determinant genes that mayplay a role in pathogenicity.