bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimal Allocation of Multi-Type Vaccines in a Two-Dose Vaccination Campaign for Epidemic Control: A Case Study of COVID-19
Authors: Zhu Jin , Wang Qing , Huang Min
Published: August 2024

As a typical case of the optimal planning for the provision of restricted medical resources, widespread vaccination is considered an effective and sustainable way to prevent and control large-scale novel coronavirus disease 2019 (COVID-19) outbreaks. However, an initial supply shortage of vaccines is inevitable because of the narrow production and logistical capacity. This work focuses on the multi-type vaccine resource allocation problem in a two-dose vaccination campaign under limited supply. To address this issue, we extended an age-stratified susceptible, exposed, infectious, and recovered (SEIR) epidemiological model to incorporate a two-dose vaccination campaign involving multiple vaccine types to fully characterize the various stages of infection and vaccination. Afterward, we integrated the proposed epidemiological model into a nonlinear programming (NLP) model to determine the optimal allocation strategy under supply capacity and vaccine hesitancy constraints with the goal of minimizing the cumulative number of deaths due to the pandemic over the entire planning horizon. A case study based on real-world data from the initial mass vaccination campaign against COVID-19 in the Midlands, England, was taken to validate the applicability of our model. Then, we performed a comparative study to demonstrate the performance of the proposed method and conducted an extensive sensitivity analysis on critical model parameters. Our results indicate that prioritizing the allocation of vaccines to elderly persons is an effective strategy for reducing COVID-19-related fatalities. Furthermore, we found that vaccination alone will not be sufficient for epidemic control in the short term, and appropriate non-pharmacological interventions are still important for effective viral containment during the initial vaccine rollout. The results also showed that the relative efficacy of the first dose is a vital factor affecting the optimal interval between doses. It is always best to complete the two-dose vaccination schedule as soon as possible when the relative efficacy of the first dose is low. Conversely, delaying the second dose of a vaccine as long as possible to increase the proportion of the population vaccinated with a single dose tends to be more favorable when the relative efficacy of the first dose is high. Finally, our proposed model is general and easily extendable to the study of other infectious disease outbreaks and provides important implications for public health authorities seeking to develop effective vaccine allocation strategies for tackling possible future pandemics.
Evaluating a Venom-Bioinspired Peptide, NOR-1202, as an Antiepileptic Treatment in Male Mice Models
Authors: Quintanilha Maria Varela Torres , Gobbo Giovanna de Azevedo Mello , Pinheiro Gabriela Beserra , Souza Adolfo Carlos Barros de , Camargo Luana Cristina , Mortari Marcia Renata
Published: August 2024

Epilepsy, a neurological disorder characterized by excessive neuronal activity and synchronized electrical discharges, ranks among the most prevalent global neurological conditions. Despite common use, antiepileptic drugs often result in adverse effects and lack effectiveness in controlling seizures in temporal lobe epilepsy (TLE) patients. Recent research explored the potential of occidentalin-1202, a peptide inspired by Polybia occidentalis venom, in safeguarding Wistar rats from chemically induced seizures. The present study evaluated the new analog from occidentalin-1202 named NOR-1202 using acute and chronic pilocarpine-induced models and an acute kainic acid (KA) male mice model. NOR-1202 was administered through the intracerebroventricular (i.c.v.), subcutaneous, or intraperitoneal routes, with stereotaxic procedures for the i.c.v. injection. In the acute pilocarpine-induced model, NOR-1202 (i.c.v.) protected against generalized seizures and mortality but lacked systemic antiepileptic activity. In the KA model, it did not prevent generalized seizures but improved survival. In the chronic TLE model, NOR-1202′s ED50 did not differ significantly from the epileptic or healthy groups regarding time spent in spontaneous recurrent seizures during the five-day treatment. However, the NOR-1202 group exhibited more seizures than the healthy group on the second day of treatment. In summary, NOR-1202 exhibits antiepileptic effects against chemoconvulsant-induced seizures, but no effect was observed when administered systemically.
Adverse Effects of Intravesical OnabotulinumtoxinA Injection in Patients with Idiopathic Overactive Bladder or Neurogenic Detrusor Overactivity: A Systematic Review and Meta-Analysis of Randomized Controlled Studies
Authors: Yu Ping-Hsuan , Wang Chung-Cheng
Published: August 2024

Despite the efficacy of onabotulinumtoxinA, its safety profile remains a concern. This meta-analysis reviewed the major adverse events (AEs) associated with intravesical onabotulinumtoxinA treatment in patients with neurogenic detrusor overactivity (NDO) and idiopathic overactive bladder (iOAB). Randomized controlled trials (RCTs) conducted between January 2000 and December 2022 were searched for adult patients administered different onabotulinumtoxinA dosages or onabotulinumtoxinA vs. placebo. Quality assessment was performed using the Cochrane Collaboration tool, and statistical analysis was performed using Review Manager version 5.3. A total of 26 RCTs were included in the analysis, including 8 on NDO and 18 on iOAB. OnabotulinumtoxinA vs. placebo significantly increased the urinary tract infection (UTI) incidence in patients with NDO (relative risk, or RR, 1.54) and iOAB (RR, 2.53). No difference in the RR with different onabotulinumtoxinA dosages was noted. Urinary retention was frequent with onabotulinumtoxinA use in the NDO (RR, 6.56) and iOAB (RR, 7.32) groups. Similar observations were made regarding the risks of de novo clean intermittent catheterization (CIC). The risk of voiding difficulty increased with onabotulinumtoxinA use in patients with iOAB. Systemic AEs of onabotulinumtoxinA, including muscle weakness (RR, 2.79) and nausea (RR, 3.15), were noted in patients with NDO; most systemic AEs had a low incidence and were sporadic.
Special Issue “Novel Diagnostic Technologies for SARS-CoV-2 and Other Emerging Viruses”
Authors: Kurosaki Yohei , Martins Danyelly Bruneska Gondim , Filho José Luiz Lima
Published: August 2024

In the last decade, extensive and borderless viral disease outbreaks have been caused by Ebola, Zika, and SARS-CoV-2 [...]
Aedes aegypti Mosquito Probing Enhances Dengue Virus Infection of Resident Myeloid Cells in Human Skin
Authors: Castanha Priscila M. S. , Azar Sasha R. , Yeung Jason , Wallace Megan , Kettenburg Gwenddolen , Watkins Simon C. , Marques Ernesto T. A. , Vasilakis Nikos , Barratt-Boyes Simon M.
Published: August 2024

The most prevalent arthropod-borne viruses, including the dengue viruses, are primarily transmitted by infected mosquitoes. However, the dynamics of dengue virus (DENV) infection and dissemination in human skin following Aedes aegypti probing remain poorly understood. We exposed human skin explants to adult female Ae. aegypti mosquitoes following their infection with DENV-2 by intrathoracic injection. Skin explants inoculated with a similar quantity of DENV-2 by a bifurcated needle were used as controls. Quantitative in situ imaging revealed that DENV replication was greatest in keratinocytes in the base of the epidermis, accounting for 50–60% of all infected cells regardless of the route of inoculation. However, DENV inoculation by Ae. aegypti probing resulted in an earlier and increased viral replication in the dermis, infecting twice as many cells at 24 h when compared to needle inoculation. Within the dermis, enhanced replication of DENV by Ae. aegypti infected mosquitoes was mediated by increased local recruitment of skin-resident macrophages, dermal dendritic cells, and epidermal Langerhans cells relative to needle inoculation. An enhanced but less pronounced influx of resident myeloid cells to the site of mosquito probing was also observed in the absence of infection. Ae. aegypti probing also increased recruitment and infection of dermal mast cells. Our findings reveal for the first time that keratinocytes are the primary targets of DENV infection following Ae. aegypti inoculation, even though most of the virus is inoculated into the dermis during probing. The data also show that mosquito probing promotes the local recruitment and infection of skin-resident myeloid cells in the absence of an intact vasculature, indicating that influx of blood-derived neutrophils is not an essential requirement for DENV spread within and out of skin.
Recent Advances in Oral Vaccines for Animals
Authors: Zhong Kaining , Chen Xinting , Zhang Junhao , Jiang Xiaoyu , Zhang Junhui , Huang Minyi , Bi Shuilian , Ju Chunmei , Luo Yongwen
Published: August 2024

Compared to traditional injected vaccines, oral vaccines offer significant advantages for the immunization of livestock and wildlife due to their ease of use, high compliance, improved safety, and potential to stimulate mucosal immune responses and induce systemic immunity against pathogens. This review provides an overview of the delivery methods for oral vaccines, and the factors that influence their immunogenicity. We also highlight the global progress and achievements in the development and use of oral vaccines for animals, shedding light on potential future applications in this field.
Finite Element Method-Peridynamics Coupled Analysis of Slope Stability Affected by Rainfall Erosion
Authors: Gu Xin , Song Laike , Xia Xiaozhou , Yu Cheng
Published: August 2024

Rainfall is a pivotal factor resulting in the cause of slope instability. The traditional finite element method often fails to converge when dealing with the strongly nonlinear fluid–solid coupling problems, making it impossible to fully analyze the sliding process under the state of slope instability. Therefore, this paper uses the coupling of peridynamics (PD) and the finite element method (FEM) to propose a data exchange mode between the seepage field and the deformation field. The influencing factors of fine particle erosion during rainfall are further considered. According to the damage mechanism of the slope sliding process to the original structure of the soil, a modified erosion constitutive relationship is proposed, which takes into account the destructive effect of plastic deformation on coarse particles. Then, the influence of rainfall duration, rainfall intensity, erosion, and initial saturated permeability coefficient on slope stability was simulated and analyzed. This paper provides a novel concept for slope stability analysis and safety evaluation under rainfall conditions.
Analysis of the Role of Aquatic Gases in the Formation of Sea-Ice Porosity
Authors: Goncharov Vadim K. , Klementieva Natalia Yu.
Published: August 2024

The porosity of freshwater ice and sea ice is one of the main parameters that determine their strength. The strength of ice varies over a wide range of values, and the differences in the intensity of the mechanisms of ice porosity formation in different water areas can be one of the possible reasons for these variations. The water mass contains gases in two forms: gases dissolved in the water mass, as well as gas bubbles that are formed when wind waves break up, and bubbles that float up from the seabed. This article presents the results of an analysis of the role of each of these forms in the formation of gas inclusions (pores) in the crystal structure of ice. The results showed that the main source of gas pores in ice crystals is the gas bubbles coming to the surface from the bottom, formed during the decomposition of bottom sediments or during gas leaks from near-bottom oil and gas fields. The possibility of gas bubbles occurring and rising to the ice–water boundary depends on the presence of bottom sources of the gases, the intensity of dissolution of the bubbles and the depth of the water area. Therefore, the variation in the porosity and the strength of ice over the space of the water areas can be associated with the changes in their depths, and the presence and location of the natural gas sources.
Virtual Gathering Platforms in Academic Teaching: Potential and Applications
Authors: Foster Sophie , Barth Larissa , Chaudhry Zaryab
Published: August 2024

The COVID-19 pandemic resulted in a rapid shift towards online learning where educators and students had to quickly adapt to new digital formats. However, the core aspects of community building and social interaction that are essential to traditional classrooms became challenging to maintain. To address this issue, we were interested in testing Virtual Gathering Platforms (VGPs) Topia and WorkAdventure to see how effectively they could be adapted to various academic teaching and learning settings. These examples of Extended Realities (XR), adopted from the 2D metaverse, aim to improve communication and interactivity in a fun and engaging way, allowing users to create immersive worlds for socialising, and collaborating. Using Technological Pedagogical Content Knowledge (TPACK), Technological Self-Efficacy (TSE) and distributed scaffolding frameworks as a guide, we created adaptable templates of both platforms that not only introduced users to how they work, but also included features flexible enough to suit various academic disciplines and promote social engagement and collaborative learning. We then implemented a case study and invited university educators teaching international courses to adapt the templates and assess them within their own learning settings. In addition, it was important for us to use the on-boarding sessions as a focal point. Here, we introduced the templates through multiple resources and offered one-to-one support to develop their use within chosen learning scenarios which ranged from an icebreaker activity to an online student resource centre. Observations then documented the adapted templates being used with students in these settings, and feedback regarding user perceptions of the platforms and the support strategies used was gathered. The study reveals the complex interplay between user experiences, support strategies, and educational frameworks, emphasising the need for adaptable and collaborative approaches to optimise these platforms in higher education.
Organization of parking space in the central part of Volgograd
Authors: Aleksikov S. V. , Leskin A. I. , Gofman D. I. , Leskina L. M. , Azroyan A. A.
Published: August 2024

An increase in the level of motorization of the population, changes in the density of residential and commercial and office buildings, the functional use of buildings and structures in areas adjacent to urban roads contribute to an increase in the intensity of motor transport and require measures to increase the capacity of the city's road network. Unauthorized parking of personal vehicles on the carriageway of streets and roads leads to a decrease in capacity, and during rush hour to an increase in accidents, which largely necessitates the organization of paid parking space, especially in the central areas of large cities. The authors analyzed the methods of calculating the cost of using paid parking in the cities of the Russian Federation, and justified the feasibility of using the methodology to calculate the cost of using paid parking in the central part of the city. Volgograd based on a comparison with an alternative tariff calculation method based on calculating the cost of creating and maintaining paid parking lots and existing tariffs for parking in large cities of the Russian Federation. The justification of the required number of parking spaces and the minimum fee for parking vehicles, depending on the size of the cars, the axial load of vehicles, the intensity of vehicle traffic in parking areas, has been carried out, the need for parking spaces has been determined. The proposed methodology is quite simple and understandable to users of highways.
Egy kísérlet a generatív mesterséges intelligenciát reprezentáló technológiával
Authors: Gyarmati Péter , Mező Ferenc
Published: August 2024

A generatív mesterséges intelligencia angolul (Artificial Generative Intelligence, AGI, magyarul MAI) technológia két változata került tesztelésre. Arra voltunk kíváncsiak mit tud önmagáról, illetve milyen képességű embereknek adhat segítséget. Figyelemmel voltunk a reklámokban és hírekben terjesztett emberfeletti képességre is. Az eredmény megnyugtató – az ember fölénye vitathatatlan! Veszély a rossz szándékú emberben van, miként eddig mindig. A technológia ebben az esetben is az ember kezében van, tőle függ hogyan és mire használja.
Didaktikai játékok a matematika oktatásában Ozobot robot felhasználásával
Authors: Szabó Tibor , Jakab Zsófia
Published: August 2024

Az alsó tagozatos tanulók játékigénye még jelentős, így tanulmányunkban a didaktikai játékokra összpontosítunk, mégpedig a matematika tantárgyon belül, emellett a játékoknak motivációs szerepet is szánunk. Didaktikai játékként tekintünk az általunk készített tevékenységekre, melyeket robotikára alapoztunk. Bemutatjuk az alkalmazott Ozobot robotot, a kidolgozott tevékenységeket, majd ismertetjük gyakorlati tapasztalatainkat.
Los conocimientos legitimados y lo común y lo diverso en documentos curriculares de la provincia de Buenos Aires.
Authors: Mendez Karlovich Maricruz
Published: August 2024

El siguiente artículo presenta algunos hallazgos vinculados a la colonialidad/decolonialidad curricular a partir del análisis de los conocimientos y saberes legitimados y los sentidos construidos alrededor de lo común y lo diverso en los Diseño Curricular de Nivel Superior para los niveles inicial y primario (2008)  y del Marco Curricular Referencial (2018) de la provincia de Buenos Aires.
Diferentes aportes teóricos y metodológicos nos permiten reconocer la vigencia e insistencia de la colonialidad y la necesidad de trabajar permanentemente en su develamiento y deconstrucción, asumiendo que el curriculum puede alentar la construcción de otras subjetividades, a partir del reconocimiento de los modos diversos de ser, estar y conocer.
Desde las epistemologías del Sur y desde una mirada decolonial, recurrimos a la sociología de las ausencias y las emergencias para identificar lo producido como no existente y las posibilidad emergentes que pueden irrumpir / insurgir / transgredir las construcciones hegemónicas.
La educación artística como herramienta de integración en entornos socioculturales vulnerables
Authors: Sánchez Daniel Jorge
Published: August 2024

FALTA
La investigación en el campo del arte
Authors: Wood Lucía , Valesini Silvina , Azaretto Clara
Published: August 2024

Este trabajo presenta algunos recorridos realizados en el marco del proyecto Lógicas de la producción de investigación en el campo del arte (2018-2020), radicado en el Instituto de Investigación en Producción y Enseñanza del Arte Argentino y Latinoamericano de la Facultad de Artes de la Universidad Nacional de La Plata (FDA-UNLP). Allí nos propusimos indagar en el desarrollo de la actividad de investigación en la FDA-UNLP, para intentar dar cuenta de los modos en que se fueron configurando trayectorias y perspectivas propias; y así aproximarnos a las problemáticas más significativas de la investigación en el campo del arte. Se desplegaron dos frentes de abordaje: en primer término, el análisis de los proyectos I+D presentados ante la Secretaría de Ciencia y Técnica entre los años 2010 y 2018 (aspecto en el que nos enfocaremos en esta ocasión), y en segundo lugar, la realización de entrevistas a directores/as de los mencionados proyectos
Radios universitarias en Argentina
Authors: Cravé Leandro , Colucci Agustina Soledad
Published: August 2024

El artículo propone un análisis del surgimiento y el panorama mediático actual de las emisoras universitarias en Argentina. Expone una descripción de la emisora Radio Universidad, de la Universidad Nacional de La Matanza, tomando diferentes propuestas teóricas, de investigaciones y personas vinculadas a la gestión de estas radios, estudiando los vínculos de estas emisoras con la universidad y con la sociedad y observando el trabajo en red y las alianzas e intercambios que se vienen realizando entre diferentes emisoras universitarias.
También presenta un recorrido por los momentos fundacionales para la consolidación de un nuevo modelo de comunicación a lo largo de estos 40 años ininterrumpidos de democracia; y ofrece una reflexión sobre los dilemas de las radios universitarias en un contexto de convergencia digital, con la mirada puesta en el futuro y hacia una comunicación inclusiva y democrática.
El ejercicio democrático de mantener viva la memoria
Authors: Lewin Miriam
Published: August 2024

Los juicios por crímenes de lesa humanidad concitaron históricamente diferentes niveles de atención en los medios de comunicación. Encontrar características atrayentes y diversas en cada uno de los procesos, así como estrategias efectivas de captación de audiencia, es un desafío para quienes trabajan en los medios de comunicación. Al estilo de Shakespeare, hay pasiones universales en cada audiencia, y situaciones con las que se puede empatizar desde lo emocional. En medio del auge de discursos relativistas y negacionistas resulta fundamental que los medios de comunicación presten cobertura especial y continua a las instancias vinculadas al proceso de memoria, verdad y justicia, en un intento de aportar a que las experiencias del pasado no se repitan.
continuidad en el poder de agrupaciones sindicales
Authors: Vieira Gravina Alejandro Andrés
Published: August 2024

En muchos sindicatos argentinos las agrupaciones oficialistas (también llamadas “listas”) han logrado perpetuarse en el poder indefinidamente, sin embargo la literatura aborda brevemente el fenómeno. Aprovechando esta vacancia el presente proyecto propone un estudio de caso explicativo sobre la Unión Ferroviaria para indagar los mecanismos que sostienen la continuidad de estas agrupaciones. Por lo tanto, la pregunta es: ¿qué mecanismos utiliza la “lista verde” para continuar en el poder? La hipótesis es la siguiente: el oficialismo posee dos mecanismos que aseguran su continuidad, reglas electorales hostiles a opositores (en especial para elecciones nacionales) y un intercambio de favores entre delegados y afiliado. El estudio está circunscripto al AMBA y al periodo 2013 – 2020. 
Para comprobar la hipótesis se utiliza como herramienta metodológica la entrevista semiestructurada y para constatar la información obtenida se apela a discursos y entrevistas periodísticas a dirigentes, delegados y trabajadores como fuente secundaria de datos.
estado y las políticas públicas: desafíos frente a la ampliación de derechos en términos de actividad física, deporte y juego.
Authors: Alonso Daniela , Uliana Santiago , Delgado Demian , Pellegrino María del Rosario , Lopez Jorge , Rodriguez Valentín , Marichalar Nair Laila , Hualpa Candelaria
Published: August 2024

A traves de una indagación cualitativa que incluyó la realización de trabajo de campo a través de una metodología etnográfica, realización de entrevistas desestructuradas y el análisis de fuentes secundarias se exponen las principales líneas de investigación y análisis que estructuraron el proyecto realizado entre agosto 2021 agosto 2022 por parte de un equipo de investigación conformado a partir del PROAPI 2021.
Se presentan los resultados de investigación organizados en torno a dos ejes principales: en primer lugar se ahonda la comprensión del Estado y la episteme donde se abordan los sentidos asignados por las normativas nacionales e internacionales que estructuran las intervenciones en materia de políticas públicas; y en segundo lugar, el Estado y los diferentes actores, instituciones y programas en relación a los cuales se construye su intervención en torno a dos tipos de acciones diferenciadas: el deporte y el juego en el espacio público.
modelos de intervención penal en el contexto de los debates democráticos actuales
Authors: Alonso Alexia Sofía
Published: August 2024

El proceso de crisis del Estado social de bienestar y la consolidación de los sistemas neoliberales fue acompañado por nuevas tendencias en materia de política criminal que tensionan progresivamente el reconocimiento de los derechos humanos de los sectores sociales más vulnerables. El artículo describe algunos de los mecanismos que apuntan a la flexibilización del sistema de garantías penales en pos de mayor ejercicio punitivo. El enfoque propuesto se centra en la política penitenciaria y la vulneración de derechos humanos, incluyendo aquellos sociales, económicos, culturales y ambientales, en el marco de los debates sobre la finalidad de la intervención penal. A su vez, se destaca el crecimiento de la intervención estatal en su faz represiva y coercitiva, en el contexto de tendencias autoritarias que surgieron en las democracias latinoamericanas durante los últimos años.
garantías institucionales de acceso a los derechos económicos, sociales y culturales
Authors: Gils Carbó Alejandra
Published: August 2024

El artículo aborda las garantías de acceso a los derechos económicos, sociales y culturales partiendo de una aproximación a las reglas constitucionales y convencionales que determinan su exigibilidad ante los poderes del Estado. Nos centraremos en la faz dinámica de las garantías institucionales, siguiendo la mirada de las ciencias sociales en cuanto enfatizan la acción participativa de la sociedad en la estructura institucional del Estado. Buscamos poner de relieve un aspecto poco atendido desde el análisis jurídico: el proceso de articulación entre agencias estatales y organizaciones de la sociedad civil que nutre la construcción de una democracia representativa. Se destaca la aptitud de esas acciones para contribuir a la solución de conflictos individuales o colectivos, ante instancias administrativas o judiciales y, a la vez, su capacidad de producir transformaciones institucionales que restituyan eficacia a la atención de los derechos económicos, sociales o culturales como piedra angular del concepto de ciudadanía.
SURFACTANT–POLYMER FLOODING: GEOCHEMICAL MONITORING OF THE PROPERTIES OF FORMATION FLUIDS AT THE IMPACT AREA
Authors: Shipaeva Maria , Sudakov Vladislav , Nurgaliev Danis , Mingazov Dinar , Startseva Anastasia
Published: August 2024

Chemical flooding methods improve oil extraction after standard waterflooding processes. Chemical EOR methods modify different properties of fluids and/or rock to mobilize the remaining oil. It is expected that the residual oil will be different in properties than conventional. A new technology is presented to study a surfactant–polymer flooding, based on a periodic sampling and measuring properties of oil and water during 15 months. The study area is a terrigenous reservoir with 3 chemical injection wells and 16 production wells. High-precision mass spectrometry methods were carried out on each sample, which made it possible to evaluate the effectiveness of ongoing work on chemical flooding. At each sampling date, 2D reservoir model was built to track these changes in the study area. It is shown that the composition of the water has changed - highly permeable channels were closed and formation waters were involved in the production. The properties of oil have also changed - depending on the site of impact, there are areas with more degraded oil in production after the injection of chemicals. Geochemical monitoring shows the redistribution of filtration flow directions in the reservoir volume.
Modelo de gestión de desarrollo sostenible para las comunidades campesinas de la región Junín (Perú)
Authors: Solís-Luis Froy , Poma-Castellanos Gualberto , Berrocal Carlos
Published: August 2024

La necesidad de un modelo de gestión del desarrollo sostenible adecuado para las comunidades campesinas, se establece debido a las limitaciones presupuestarias que afectan la viabilidad de sus actividades económicas tradicionales, organización careciente de estructuras claras para la toma de decisiones, y serias afectaciones ambientales causadas por actividades industriales comprometiendo sus recursos naturales y sustentabilidad. Estas problemáticas subrayan la necesidad de elaborar y determinar el impacto del modelo de gestión de desarrollo sostenible en las comunidades campesinas de la región Junín. Por medio de un método combinado de enfoques centrando su estudio en 60 principales comunidades campesinas se recolectó la información por medio de un guía de entrevista y cuestionario, analizando su información por medio de técnicas descriptivas. El diagnóstico de las comunidades campesinas reveló un alto grado de desacuerdo en la gestión comunitaria, insuficientes ingresos económicos y nula efectividad de las políticas de gestión ambiental. La contribución de las comunidades se centró principalmente en el aspecto social, priorizando necesidades inmediatas como educación y salud. Antes de la implementación del modelo, los puntajes eran bajos, tras la implementación del modelo, se observó una mejora sustancial. Se concluye existe un impacto positivo debido a la integración eficaz de las necesidades y expectativas comunitarias en las políticas de desarrollo y mejoras en la cohesión social, la estabilidad económica y la conservación del medio ambiente, lo que implica que no solo se debe abordar problemas inmediatos, sino que es necesario establecer una base para el crecimiento sostenido y equitativo a largo plazo.
Gestión municipal y comercio informal en una provincia de la región Junín (Perú)
Authors: Solís-Luis Froy , Hurtado-Meza Máximo
Published: August 2024

La expansión del comercio informal está exacerbada por la crisis económica y falta de empleo formal, manifestándose en la ocupación desordenada de espacios públicos. Ante ello, las autoridades se encuentran en el desafío de equilibrar la necesidad de una integración económica, orden público y desarrollo urbano. En respuesta a ello, se establece la intención de determinar la relación entre la gestión municipal y el comercio informal en la provincia de Huancayo, Junín. Por medio de un enfoque medible correlacional, aplicando un cuestionario a 386 comerciantes, se demostraron los resultados al aplicarse el Chi cuadrado. Los resultados indican que los comerciantes informales perciben negativamente la efectividad de la gestión municipal ante la falta de fomento del crecimiento comercial y la formalización, considerando moderado (41%) planificación y organización. Además, el 50% atribuye el descontrol al comercio informal debido a la falta de regulación en espacios públicos. Aunque se implementan medidas policiales, su eficacia es limitada (57%) debido a la corrupción y la inconsistencia en la ejecución de políticas. No obstante, se reconoce el valor de la economía informal como fuente esencial de ingresos para familias vulnerables. En ese sentido, se confirma su relación (p-valor < 0.05) positiva, de acuerdo que a medida que la gestión municipal se intensifica o mejora, también aumenta la reducción del comercio informal. Por lo tanto, se concluye que existe una relación significativa positiva, el cual implica que mejorar la efectividad de las políticas municipales y fomentar un ambiente más seguro, está asociado con la regulación y prevalencia del comercio informal.
Relato de Experiência
Authors: Ribeiro de Almeida Vilma , Lorencini Diocilde , Lira Moura Teixeira Lucélia , Braga Steindorf Amábia
Published: August 2024

Este texto relata a experiência desenvolvida a partir da prática pedagógica utilizando a construção de paródias, tratando da temática referente ao meio ambiente e sustentabilidade. Desenvolveu-se uma atividade com crianças da Educação Infantil, seguimento pré-escolar, e com uma turma do 5º período do curso de Licenciatura em Matemática e Química, com o objetivo de investigar o uso de paródias como estratégia de ensino e aprendizagem. Constatou-se que a prática pedagógica foi uma experiência exitosa, pois contribuiu com a formação dos estudantes e possibilitou a ruptura com as metodologias pré-estabelecidas para o ensino e a construção de outras formas de aprendizagens. Ademais, essa atividade permitiu que as crianças e os jovens envolvidos na realização da prática pedagógica se envolvessem com a temática proposta e construíssem saberes autônomos, integrativos e criativos, além de viabilizar a experiência da musicalidade no ensino.
Penerapan Desain UI/UX dalam Pengembangan Aplikasi Administrasi Keuangan Logistik untuk Efisiensi Operasional di PT Prima Cipta Express dengan Metode Design Thinking
Authors: Satriyo Teguh , Razaq Jeffri Alfa
Published: August 2024

In the current digital era, information technology and software applications are important for increasing operational efficiency in the business world, especially in the fields of logistics and financial management. Ineffective management of logistics financial administration can result in increased costs, delays in delivery, and even inaccuracies in financial reports. Therefore, this research was conducted with the aim of overcoming operational efficiency challenges for PT Prima Cipta Express. One approach that can be taken to overcome this challenge is to apply the Design Thinking method which includes the Empathize, Define, Ideate, Prototype and Test stages. At the testing stage, this research uses usability testing and SUS (System Usability Scale) calculations which are useful for testing prototype usability. This research, testing involved a prototype user experience using Task Scenario. Usability test results according to the System Usability Scale (SUS) calculations reached 86, which is at a good level (grade B) and is included in the "Excellent" category. These results indicate that users positively evaluate the ease of use of the application. Referring to the average SUS score of 68, it can be concluded that this application design is well received by users and is suitable for use.
Comparative Analysis of Bank Performance Between Bank Syariah Indonesia (Private-Shariah) and Bank Central Asia (Private-Conventional) Period of 2021 and 2022
Authors: Widyanto Muhammad Laras , Alfia Yulis Diana , Kurniawati Sri , Marhalinda Marhalinda
Published: August 2024

Bank Syariah Indonesia (BSI) is the largest sharia bank in Indonesia, while Bank Central Asia (BCA) is a conventional private bank with the largest capitalization in Indonesia. The fundamental problem at BSI is a cyber attack that has an impact on the IT system, while the fundamental problem at BCA bank is that the mobile banking system will be disrupted in 2022, so researchers will compare the bank's performance in 2021 (before) and 2022 (after). The general objective of this research is to analyze the comparison of bank performance after experiencing technological obstacles from both internal and external sources, while the specific objectives are to find out whether: (1) Any difference in the performance of Bank Syariah Indonesia (Private-Syariah) between 2021 and 2022, (2) Any difference in the performance of Bank Central Asia (Private-Conventional) in 2021 and 2022, (3) Any difference in the performance of Bank Syariah Indonesia (Private-Sharia) and Bank Central Asia (Private Conventional) between 2021 and 2022. The method used in this research is RGEC (Risk Profile, Good Corporate Governance, Earning, Capital). The analytical tool used is the Wilcoxon and Mann Whitney non-parametric t-difference test. The results obtained are: 1. There is no difference in Bank BSI's performance before and after the IT problem but not constant; 2. There is no difference in Bank BCA's performance before and after the IT problem but not constant; 3. There is no difference in the performance of Bank BSI before and BCA before IT problems occur but are not constant;4. There is no difference in the performance of Bank BSI after and BCA after IT problems occur but are not constant.
The Impact of Ulnar Styloid Fractures on Patient Functional Outcomes and Complication Rates in Distal Radius Fractures Treated with Volar Locking Plates: A Comparative Study
Authors: Tantia Dr. Yash Kumar , Butala Prof. Dr. Rajendra R.
Published: August 2024

This study evaluated the effects of ulnar styloid fractures on functional recovery and complication rates in 200 patients with distal radius fractures treated with volar locking plates. Participants were categorized into groups with (USF) and without (NUSF) ulnar styloid fractures, assessing outcomes like grip strength, range of motion, DASH scores, PRWE scores, and complication rates over 12 months. Results indicated that ulnar styloid fractures marginally reduced grip strength and increased DASH and PRWE scores and complication rates, suggesting a minor but significant impact on recovery. No difference in range of motion was observed. These findings advocate for a selective approach to ulnar styloid fracture fixation, emphasizing personalized patient management. Further research is recommended to refine treatment guidelines and explore long-term outcomes, highlighting the importance of considering ulnar styloid fractures in clinical decisions to optimize patient recovery.
Assessment of Plasma Homocysteine in Patients with Hypothyroidism in a Nigerian Tertiary Hospital
Authors: S Dalili M. , M Hadiru G. , M Dungus M. , K Aisha S. , A Amali A. , A Hassan A. , M Gademi F. , L Fatima M. , A Halima M. , H Musa A. , S Mshelia D.
Published: August 2024

Introduction: Hypothyroidism, a risk factor for atherosclerotic cardiovascular disease has been seen to be associated with hyperhomocysteinemia. The plasma levels of homocysteine and its relationship with hypothyroidism was assessed. Material and Methods: A total of 120 patients aged 20 – 60 years comprising of 60 hypothyroid and 60 euthyroid controls were assessed for the study. Evaluation of plasma homocystein was done using human homocysteine ELISA my BioSource. FT3, FT4 and TSH were also evaluated by enzyme linked immunosorbent assay (ELISA) technique using stat fax-2100. Result: In our study, we have found the values of FT3 in the subjects as 1.21+ 0.89pg/ml lower than controls values of 1.92+0.66pg/ml, values of FT4 in subjects as 0.60+0.53ng/dl as compared to control group value of 1.40+0.30ng/dl, values of TSH as 2.07+1.19µiU/ml higher than the control group of 0.48+1.67µiU/ml. The mean values of plasma homocysteine (Hcy) for subjects was 34.50+10.01µmol/L higher than the control group with 9.30+2.11µmol/L. Conclusion: Our study findings suggest that patients with hypothyroidism also have a high plasma homocysteine known to pose cardiovascular complications.
Strategy to increase the growth of sweet banana varieties of chili (Capsicum sp) using Gamma Ray Radiation
Authors: Aidil Riwanda Danang , Hartati Yusida Saragih Siti , Hariyati Adam Dini , Ayu Putri Septyani Ika
Published: August 2024

Chili (Capsicum sp) is a herbaceous plant from the eggplant family and is thought to originate from Mexico, Central America, and the Andes region in South America. This research was carried out from November 2023 to May 2024. Sweet Banana Variety Chili Seeds were sent to the Isotope Application Center and Radiation (PAIR), National Nuclear Energy Agency (BATAN) Jl. Lebak Bulus Raya No.49 Cilandak-South Jakarta. Irradiated seeds were planted in the Green House of Labuhanbatu University, Labuhanbatu Regency, North Sumatra. The design used was a non-factorial completely randomized design (CRD) with 5 replications. The experiment used a single factor, namely gamma rays, on sweet banana variety chili seeds with 4 treatment levels: Control (0 Gy), 100 Gy, 200 Gy, 300 Gy. In this study, 20 plant units were observed. Based on the results of observations of the growth of sweet banana variety chili seedlings, seedling growth was different in each treatment, and most of the seedlings were only able to survive at an irradiation level of 100 Gy. The results of the analysis of variance showed that the gamma-ray radiation factor was significantly different from the number of leaves (strands) in the 2nd week after planting, but was not significantly different 4 weeks after planting. The results of the analysis of variance showed that the gamma-ray radiation factor was significantly different 2 weeks after planting, a further DMRT test was carried out at a level of 5%.
Spread of quarantine plant pests in Ukraine
Authors: Holiachuk Yu. , Kosylovych H.
Published: August 2024

Goal. Of article is analyse of spreading dynamics of insect species with the quarantine status for Ukraine territory based on data of the State Service of Ukraine on Food Safety and Consumer Protection.
Methods. The work used official data on the distribution of plant quarantine organisms, which were interpreted using the analytical and comparative method of research.
Results. The development of insect species with status of locally presented (list A-2 of the List of regulated harmful organisms) and species with status of absent (list A-1) in Ukraine was detected during 2015—2023. By data of State Service of Ukraine on Food Safety and Consumer Protection, the areal of American white moth, western corn rootworm and South American tomato moth have increased, while the spreading area of potato moth, and western flower thrips have decreased. These species have status of locally presented in Ukraine. The Mediterranean fruit fly belongs to list A-1, but its spreading area was detected in Odessa region during 2015—2023, and from 2022, some increase of spreading was noted. State Service of Ukraine on Food Safety and Consumer Protection fixes the increasing of tobacco whitefly (list A-1) area. The rapid spread of emerald ash borer are noted in Ukraine from 2019, and brown marmorated stink bug are presented in Ukraine in 2023.
Conclusions. According to the results of the analysis of the distribution of quarantine insect species, an increase in the areas inhabited by American white moth, western corn rootworm, South American tomato moth, Mediterranean fruit fly, tobacco whitefly, as well as the appearance of the previously absent emerald ash borer and brown marmorated stink bug on the territory of Ukraine were established. In order to prevent the spread of quarantine pests, business entities whose activities may contribute to the spread of quarantine organisms must strictly adhere to the state policy in the field of plant quarantine.
Understanding Digital Rights in An Era of Digital Politics in Africa
Authors: Maseko Maxwell
Published: August 2024

As more African countries connect their citizens to the Internet and other digital technologies in a bid to improve services, questions are being asked about the protection of human rights for nationals online. The wake of the COVID-19 pandemic forced many countries on the continent to search for alternative ways to provide services. Varying national shutdowns also impacted democratic processes like elections and accompanying actions such as voter registration and campaigning. This paper aims to assess the trends and challenges around the implementation of digital rights and propose the way forward for scholars and practitioners promoting digital rights. Data was collected using desktop research to identify and assess common themes and differences across the continent. The results show that as technologies continue evolving at a fast pace, it is fundamental for African governments to reassess and adapt their laws to maintain and protect the rights of their citizens online.
The Usability of e-Government as a Mechanism to Enhance Public Service Delivery in the South African Government
Authors: Nkgapele Simon Matome
Published: August 2024

In the digital age, the electronic government has emerged as a transformative mechanism for ameliorating service delivery, promoting transparency, and promoting citizen participation. South Africa is rich in diversity and evolving in its socio-economic landscape, and it encounters unique difficulties in providing services to the society. The difficulties in service delivery are an important difficulty for the Government of South Africa because this problem spreads from local to national governments. Consequently, these often lead to countless issues, including protests concerning service delivery that usually result in property losses. Therefore, the introduction of e-government serves as a tool to foster efficient and effective service delivery. The purpose of this paper was to identify current barriers, successes, and areas for amelioration in the execution of digital government in South Africa. Therefore, the main focus was on the use of electronic government as a tool to ameliorate service delivery in South Africa. This paper identified the several current difficulties and successes of digital government practices across South Africa to seek preventive and corrective measures to ensure that the usage of e-government can be efficient and effective in delivering public services. The researcher employed a qualitative methodology and relied heavily on secondary data to generate a rich grasp and knowledge of the lessons learned from e-government practices in South Africa. The outcomes of this paper indicated that South Africa has made significant progress in implementing digital government initiatives. Although successful digital government initiatives are being implemented in South Africa, problems such as digital divisions, ICT personnel shortages, limited digital literacy, resistance to technological innovation and infrastructure limitations continue to exist. If these barriers and difficulties are not addressed adequately, the future of the South African digital government is at risk, and the implementation of electronic government initiatives to foster effective service delivery will be a mere dream.
PENGARUH PELATIHAN CASE MANAGER TERHADAP KEPUASAAN PASIEN DI RUANG RAWAT INAP INTERNIS RSU SEMBIRING TAHUN 2023
Authors: Putri Dian Primadia , Purba Amril , Perangin-angin Gundur
Published: August 2024

based totally on an preliminary survey carried out through researchers, the range of patients inside the IVI Inpatient Room changed into 25 human beings with case managers who had schooling and JASMINE as many as 25 humans with case managers who had not had training. With BPJS status in 2022 (January- September). based totally on information taken from medical facts, certainly one of them is dissatisfaction with the services of nurses and medical doctors and different case managers for the services of inpatients. This research is expected to help optimize the function of case managers as coordinators of nursing services. Hospitals want a layout or approach so that it will carry out a non-stop provider process. One such version of care is the case manager. Case managers who're generally responsible for the coordination and continuity of affected person care while in health facility. The pattern used became Non- chance sampling with saturated sampling technique (census) which was executed in patients in room IVI as the Intervention institution of 25 humans and the JASMINE room as the manage organization of 25 human beings which changed into carried out in December 2023 to February 2023. As for The consequences acquired from this study are that there's an impact of Case supervisor training on affected person pride in the inner Inpatient Room at Sembiring hospital in 2023, each of which has a p- value of 0.001 zero.05 within the Tangibles, Empathy, Reliability, Responsiveness, assurance categories. the results of the Manova check additionally show a significance fee of 0.001 <0.05, so it may be concluded that there is an effect of case manager schooling on affected person delight within the Rau Sembiring Internist Inpatient Room in 2023.
PENGARUH PEMBERIAN LABU SIAM TERHADAP PENURUNAN TEKANAN DARAH
Authors: Sitepu Marlen Sadrina , Sihaloho Wilfa Muslimah , Krisna Putri , Insani Septa Dwi , Sitorus Husna Sari
Published: August 2024

Hyepertension in Indonesia is caused by a lifestyle that consumes foods with higt cholesterol levels, foods with higt salt content, lack of exercise and cannot be separated from genetic factors. Elderly is a period where individuals have entered a period of physical decline which is characterized by wrinkled skin, gray hair, missing teeth, hearing loss, blurred vision, and excessive body proportions, so that it is said that elderly are individuals in this age group who have entered a period of physical decline final stage of their life.