bluuebunny/crossref_metadata_2025 huggingface dataset:
Scattering of partially coherent vortex beam by rough surface in atmospheric turbulence
Authors: Dong Kangjun , Cheng Mingjian , Lavery Martin P. J. , Geng Siqi , Wang Ping , Guo Lixin
Published: January 2022

A double-passage propagation model of partially coherent Laguerre-Gaussian (LG) vortex beams with orbital angular momentum (OAM) modes in turbulent atmosphere after scattering from Gaussian rough surfaces was formulated. Rough surface scattering had a weak effect on the spreading of a vortex beam in turbulent atmosphere. However, it severely influenced the phase on this beam, rapidly reducing the original OAM mode’s relative intensity. The OAM spectrum information is more useful than the intensity information for rough surface object remote sensing. Additionally, by comparing the scattering intensity in monostatic and bistatic systems, the enhanced backscatter of vortex beams from Gaussian rough surfaces was verified.
Goos-Hänchen shift at Brillouin light scattering by a magnetostatic wave in the Damon-Eshbach configuration [Invited]
Authors: Dadoenkova Yuliya S. , Krawczyk Maciej , Lyubchanskii Igor L.
Published: January 2022

The lateral shift of an optical beam undergoing Brillouin light scattering by a spin wave propagating along the interface between magnetic and dielectric media (Damon-Eshbach configuration) in the total internal reflection geometry is studied theoretically. Linear and quadratic magneto-optic terms in polarization are taken into account. It is shown that the lateral shift depends on the polarization (s- or p-) state of the scattered electromagnetic wave as well as on the frequency of the spin wave.
A novel approach of overtaking maneuvering using modified RG method
Authors: Ghumman Usman , Jabbar Hamid , Tiwana Mohsin Islam , Khalil Ihsan Ullah , Kunwar Faraz
Published: January 2022

Intelligent and safe overtaking maneuvering is always a challenging task for autonomous vehicles. This paper proposes and experimentally implements a novel approach of overtaking maneuvering using modified form of Rendezvous Guidance (RG) algorithm for trajectory planning and obstacle avoidance, considering driver safety and comfort during autonomous overtaking. The simulations for all possible scenarios are conducted to ensure the effectiveness of proposed modified RG algorithm. These scenarios involved presence and absence of obstacle vehicle in overtaking lane alongside leading vehicle in driving lane. In addition, the enhanced performance of modified RG algorithm is established over conventional RG algorithm by comparative analysis. The results indicate that overtaking maneuvering period could be decreased by 10% using a modified RG algorithm and vehicle will cover less distance to complete overtaking. The efficacy of proposed method is justified by performing experiments using mobile robots. The experimental results and simulation results of modified RG algorithm are compared, and their plots are almost identical.
Latex-injected, non-decapitated, saturated salt method-embalmed cadaver technique development and application as a head and neck surgery training model
Authors: Durongphan Anuch , Suksantilap Songsak , Panrong Nutthanun , Aungsusiripong Aimpat , Wiriya Apipat , Pisittrakoonporn Sasiprapa , Pichaisak Witchate , Pamornpol Benjaporn
Published: January 2022

Published cerebrovascular injection techniques have mostly used decapitated, fresh cadavers or heads embalmed with 10% formaldehyde. There have been no reports using vascular-injected cadavers for head and neck surgical training models or using vascular injections in saturated salt method-embalmed cadavers. Thus, we performed vascular labeling of five saturated salt method-embalmed cadavers without decapitation. Latex mixed with red ink was injected into the common carotid artery via a 3D-printed vascular adapter. The injection force was provided by a peristaltic pump. Thyroidectomy, submandibular gland excision, neck dissection, parotidectomy, and mandibulotomy were performed on both sides of each cadaver (n = 10). The consistency of the cadavers was softer than fresh ones. Subcutaneous tissues were well preserved, and muscles were moist and elastic. Five physicians graded the resemblance of the heads and necks of the latex-injected, saturated salt method-embalmed, non-decapitated of five cadavers compared to living humans using a Likert scale from 0 (no resemblance) to 5 (maximum resemblance). Fifty-two percent of the head and neck region resemblance scale ratings were four or five. Although the cadavers were practical for head and neck surgical simulations, the brain parenchyma was only partially preserved and unsuitable for use. The most distal arterial branches reached by the injected latex were measured. The external caliber of the smallest vessels reached were lacrimal arteries (mean caliber ± SD, 0.04 ± 0.04 mm; 95% CI [0, 0.09]). There were no significant differences in the mean caliber of the smallest vessels reached between the left- and right-sided arterial branches (all p < 0.05).
Depois da pós-esfera pública
Authors: Schlesinger Philip
Published: January 2022

A ideia de esfera pública tem sido central, desde há muito tempo, para a discussão da comunicação política. A sua presente condição é o tema deste ensaio. O debate sobre a esfera pública tem sido marcado pelo policiamento de fronteiras de sistemas políticos e ideologias concorrentes. A atual discussão reflete a transição acelerada da era dos mass media para a era do entrincheiramento ramificado da Internet. Tem sido também influenciada pela análise em voga do populismo. A presente fase de transição, cujo resultado permanece indefinido, tem na ideia de uma “pós-esfera pública” instável a sua melhor descrição. Esta instabilidade não é fora de comum, pois, ao longo do tempo, as conceções sobre os fundamentos e o escopo da esfera pública registaram constantes alterações. Lateralmente, as respostas dos Estados ao desenvolvimento da Internet deram origem a uma nova alteração de foco, a “viragem regulatória”. É provável que isto venha a influenciar a forma futura da esfera pública.
Visual Symmetrical effects on the human brain
Authors: Sharma Shubhangi
Published: January 2022

The human brain is a very complicated machine. In this paper, we present a new way of the interpretation that explains how the brain reacts to the presented symmetrical figures.
Entire solutions for several complex partial differential-difference equations of Fermat type in ℂ2
Authors: Gui Xian Min , Xu Hong Yan , Tang Wen Ju , Wang Hua
Published: January 2022

By utilizing the Nevanlinna theory of meromorphic functions in several complex variables, we mainly investigate the existence and the forms of entire solutions for the partial differential-difference equation of Fermat type

α

∂
f

(

z

1

,

z

2

)

∂

z

1

+
β

∂
f

(

z

1

,

z

2

)

∂

z

2

m

+
f

(

z

1

+

c

1

,

z

2

+

c

2

)

n

=
1

{\left(\alpha \frac{\partial f\left({z}_{1},{z}_{2})}{\partial {z}_{1}}+\beta \frac{\partial f\left({z}_{1},{z}_{2})}{\partial {z}_{2}}\right)}^{m}+f{\left({z}_{1}+{c}_{1},{z}_{2}+{c}_{2})}^{n}=1

and

α

∂
f

(

z

1

,

z

2

)

∂

z

1

+
β

∂
f

(

z

1

,

z

2

)

∂

z

2

2

+

[

γ

1

f

(

z

1

+

c

1

,

z

2

+

c

2

)

−

γ

2

f

(

z

1

,

z

2

)

]

2

=
1
,

{\left(\alpha \frac{\partial f\left({z}_{1},{z}_{2})}{\partial {z}_{1}}+\beta \frac{\partial f\left({z}_{1},{z}_{2})}{\partial {z}_{2}}\right)}^{2}+{\left[{\gamma }_{1}f\left({z}_{1}+{c}_{1},{z}_{2}+{c}_{2})-{\gamma }_{2}f\left({z}_{1},{z}_{2})]}^{2}=1,

where

m
,
n

m,n

are positive integers and

α
,
β
,

γ

1

,

γ

2

\alpha ,\beta ,{\gamma }_{1},{\gamma }_{2}

are constants in

C

{\mathbb{C}}

. We give some results about the forms of solutions for these equations, which are great improvements of the previous theorems given by Xu and Cao et al. Moreover, it is very satisfactory that we give the corresponding examples to explain the conclusions of our theorems in each case.
Matrix representation of a cross product and related curl-based differential operators in all space dimensions
Authors: Lewintan Peter
Published: January 2022

A higher dimensional generalization of the cross product is associated with an adequate matrix multiplication. This index-free view allows for a better understanding of the underlying algebraic structures, among which are generalizations of Grassmann’s, Jacobi’s and Room’s identities. Moreover, such a view provides a higher dimensional analogue of the decomposition of the vector Laplacian, which itself gives an explicit index-free Helmholtz decomposition in arbitrary dimensions

n
≥
2

n\ge 2

.
Novel Glial Cells Missing-2 (GCM2) variants in parathyroid disorders
Authors: Canaff Lucie , Guarnieri Vito , Kim Yoojung , Wong Betty Y L , Nolin-Lapalme Alexis , Cole David E C , Minisola Salvatore , Eller-Vainicher Cristina , Cetani Filomena , Repaci Andrea , Turchetti Daniela , Corbetta Sabrina , Scillitani Alfredo , Goltzman David
Published: January 2022

Objective

The aim of this study was to analyze variants of the gene glial cells missing-2 (GCM2), encoding a parathyroid cell-specific transcription factor, in familial hypoparathyroidism and in familial isolated hyperparathyroidism (FIHP) without and with parathyroid carcinoma.

Design

We characterized 2 families with hypoparathyroidism and 19 with FIHP in which we examined the mechanism of action of GCM2 variants.

Methods

Leukocyte DNA of hypoparathyroid individuals was Sanger sequenced for CASR, PTH, GNA11 and GCM2 mutations. DNA of hyperparathyroid individuals underwent MEN1, CDKN1B, CDC73,
CASR, RET and GCM2 sequencing. The actions of identified GCM2 variants were evaluated by in vitro functional analyses.

Results

A novel homozygous p.R67C GCM2 mutation which failed to stimulate transcriptional activity in a luciferase assay was identified in affected members of two hypoparathyroid families. Oligonucleotide pull-down assay and in silico structural modeling indicated that this mutant had lost the ability to bind the consensus GCM recognition sequence of DNA. Two novel (p.I383M and p.T386S) and one previously reported (p.Y394S) heterozygous GCM2 variants that lie within a C-terminal conserved inhibitory domain were identified in three affected individuals of the hyperparathyroid families. One family member, heterozygous for p.I138M, had parathyroid carcinoma (PC), and a heterozygous p.V382M variant was found in another patient affected by sporadic PC. These variants exerted significantly enhanced in vitrotranscriptional activity, including increased stimulation of the PTH promoter.

Conclusions

We provide evidence that two novel GCM2 R67C inactivating mutations with an inability to bind DNA are causative of hypoparathyroidism. Additionally, we provide evidence that two novel GCM2 variants increased transactivation of the PTH promoter in vitro and are associated with FIHP. Furthermore, our studies suggest that activating GCM2 variants may contribute to facilitating more aggressive parathyroid disease.
Activin A causes endothelial dysfunction of mouse aorta and human aortic cells
Authors: Barber Courtney , Yap Yann , Hannan Natalie J , Wallace Euan M , Marshall Sarah A
Published: January 2022

Preeclampsia is a multisystem hypertensive disorder of pregnancy that remains one of the leading causes of maternal and perinatal morbidity and mortality worldwide. The widespread maternal endothelial dysfunction that underlies preeclampsia is thought to arise from excessive placental production of various factors combined with enhanced oxidative stress. While previous studies have reported elevated activin A in women diagnosed with preeclampsia, whether activin A can cause vascular dysfunction has not yet been thoroughly investigated. Here, we demonstrated that different subtypes of activin A receptors were localised to the endothelial and smooth muscle cells of mouse and human aortae. Then, the aorta of healthy female C57Bl6J mice (n = 8) were incubated for 24 h in various concentrations of recombinant activin A to mimic early pregnancy (5 ng/mL), late pregnancy (20 ng/mL) and preeclampsia (50 ng/mL). Vascular reactivity as assessed by wire myography revealed that only the preeclamptic level of activin A impaired agonist-mediated endothelium-dependent relaxation by reducing the vasodilator prostanoid contribution to relaxation. However, agonist-mediated endothelium-independent mechanisms were unaffected. Further investigations carried out on human aortic endothelial cells suggested that the impairment of aorta relaxation could also be driven by increased endothelial cell permeability, and decreased cell viability, adherence and proliferation. This is the first direct evidence to show that activin A can induce endothelial dysfunction in whole blood vessels, suggesting that at high circulating levels it may contribute to the widespread endothelial dysfunction in women with preeclampsia.
Humanizados: una danza colectiva desde los y las estudiantes
Authors: Morúa Carrillo Carlos Fernando
Published: January 2022

The group Humanizados, from the Centro de Estudios Generales de la Universidad Nacional [Center for General Studies of Universidad Nacional], Costa Rica, shows how the task of stimulating and raising awareness in regards to the discipline of dance is carried out through art and culture, bringing it closer to the university community, with special emphasis on the students who study at the Centro.This task has been by creating a dance group, a creative space that develops a task of dissemination and extension through various actions since 2012. These actions include the creation of artistic performances, workshops, and lectures. They put students in contact with the art of movement, allowing them to obtain comprehensive training to understand humanism as knowledge and as a way of life; so the students can consider themselves as human beings concerned about their environment and their reality while studying at the Center for General Studies.Teaching-learning processes, carried out with the members of Humanizados, are facilitated through the number of workshops conducted with a diversity of teachers. These workshops allow interaction, solidarity and teamwork, and the achievement of common objectives; they encourage discipline, the development of skills and abilities in dancers who explore new possibilities of movement from their own bodies, having recourse to creativity, originality, and innovation. They also contribute to awakening new horizons and new experiences to discover, with their body and mind, the experience of the new. Standing on stage in front of an audience allows them to experience stage fright; in the future, this experience will let them be potential audiences to go to the theater.Since 2012, these processes have been carried out thanks to the participation of fifty-five students in the dance group Humanizados throughout this time, the staging of more than thirty-five choreographies, the active participation of twelve national and international teachers through workshops, and the organization of fifteen artistic performances, twice a year, showcased in the Clodomiro Picado Auditorium of the Universidad Nacional de Costa Rica. The experience also included the participation as organizers of five International artistic-humanist meetings, through lectures, talks, shows, and artistic workshops, with the participation of Latin American countries, in the city of Heredia, and numerous university extension presentations in communities within the country. Besides, seven international tours with the group in Nicaragua, El Salvador, Honduras, and Mexico extended the learning experience.Art is an excellent way to stimulate a culture of peace, strengthen self-esteem and security in the individual, and keep people away from vices and drugs. Thanks to the meetings, it has been possible to consolidate and coordinate interdisciplinary teams with the five state universities and governmental and non-governmental bodies. Undoubtedly, it is a significant learning experience for their lives.
¿Qué respiramos? La construcción de saberes y conciencia ambiental entre la universidad y la escuela secundaria, a través de la extensión universitaria
Authors: Isaguirre Andrea Celeste , Moyano Mario Franco , Daguerre Aldo , Matilde Moglia Marta
Published: January 2022

This work aimed to address an environmental problem related to human health to respond to students and teachers’ concerns from two secondary schools in the city of San Luis (Argentina). These concerns originated from secondary school social actors’ who desired to know the biological quality of the air they breathe daily in the environments in which they carry out their school activities. Through joint work between the extension team of the Faculty of Chemistry, Biochemistry, and Pharmacy of the National University of San Luis and the school community, it was sought to build knowledge related to environmental education in a dialogic framework. While developing this work, discussion and reflection on the use of ornamental plant species in the city’s green spaces and their impact on public health were encouraged. The proposed methodology included face-to-face workshops, for which theoretical-practical guides were prepared, appropriate to the academic level of the students and specific to the topics to approach in this work. The knowledge obtained was successfully applied in simple experimental activities related to research tasks in Aerobiology at the university. Thus, the students could participate in the generation of useful knowledge for themselves, the extension team, and the community of San Luis, in general.
Fomento de la seguridad alimentaria y nutricional y de la soberanía alimentaria en unidades de producción familiar del cantón de Siquirres, provincia de Limón
Authors: Aguirre Rosales Diego , Aiza Ajoy Amelia
Published: January 2022

The project was developed in Siquirres, a canton of the Limón province. The process consisted of training, learning by doing, and the dialogue of knowledge systems to promote the production of twenty-five food security and nutrition crops to promote food sovereignty in the production units of thirty-four families and a school in the marginal rural territory of the mentioned canton. The process included the participation of two organizations of producers, public institutions, the National University, and advanced students of the Agronomy career of the School of Agricultural Sciences of the National University.
La cadena de valor en la productividad de las microempresas, pequeñas empresas y medianas empresas en el contexto de la COVID-19
Authors: Rios Delgado Teresa Jesús
Published: January 2022

La cadena de valor está conformada por las actividades que crean valor agregado para transformar un producto o servicio en creación de valor y comprende desde su producción hasta su comercialización. De esta manera, el análisis de la cadena de valor en una empresa permite realizar un diagnóstico situacional en cuanto a la capacidad de generación de valor para la empresa. En consecuencia, podría afirmarse que la cadena de valor constituye la piedra angular de la productividad y también es considerada como una herramienta estratégica en la gestión de las empresas a fin de que estas logren una ventaja competitiva, optimizando sus recursos y actividades para lograr el posicionamiento de la empresa en el mercado. Este ensayo analiza la cadena de valor como una oportunidad en el entorno y contexto del COVID-19 y presenta los fundamentos teóricos y reflexiones que pueden ser aplicados en cualquier tipo de empresa sin importar la dimensión que esta pueda tener.
El taller del historiador
Authors: Montoya Rivas Gustavo
Published: January 2022

En esta brevísima remembranza, sería imposible dar cuenta de más de medio siglo de actividades ininterrumpidas del Seminario de Historia Rural Andina, pero en cambio sí es posible afirmar, que todos los que tuvimos la oportunidad y privilegio de investigar al lado de Pablo Macera, nos beneficiamos de todo ese caudal simbólico y material que se congregaba en las instalaciones del antiguo Colegio Real de San Marcos. Como la mayoría de mi generación, cuando ingresamos a la universidad a fines de la década de los ochentas del siglo XX, muy pronto fuimos embargados por una mezcla de entusiasmo y curiosidad en torno a las actividades y publicaciones que Macera y el Seminario de Historia Rural Andina, por supuesto, desarrollaban pertinazmente, desde mucho antes que nosotros ingresásemos a la universidad.
Estudio seroepidemiológico de Toxoplasma gondii en caprinos del Perú y su asociación a factores de riesgo
Authors: Chávez V. Amanda , Pinedo V. Rosa , Suárez A. Francisco , Villacaqui A. Eglinton , Pérez C. Ibelice
Published: January 2022

El objetivo del estudio fue determinar la seroprevalencia y su asociación con los factores de riesgo en la infección por Toxoplasma gondii en caprinos del Perú. Se trabajó con un grupo de 1119 sueros de caprinos colectados entre 2017-2018 de 23 de los 24 departamentos del país por el Servicio Nacional de Sanidad Animal (SENASA) para un monitoreo de Brucella melitensis. El número de muestras fue proporcional a la población de cabras de cada departamento. Se consideraron las variables edad (<1, 1-3, >3 años), sexo, procedencia (Zona Costa Norte, Zona Costa Centro-Sur, Zona Sierra-oriente, altitud (0-500, >500-2500, >2500 msnm) y tipo de crianza (intensiva, extensiva). Los sueros fueron analizados con un kit comercial de ELISA indirecta multi-especie y los factores de riesgo se determinaron mediante regresión logística. La prevalencia general encontrada de T. gondii fue de 28.15% (IC 95%: 25.5-30.9). La mayor prevalencia se encontró en la Sierra-oriente y Costa Centro-Sur), a una altitud <2500 msnm y bajo crianza intensiva.
Nuances of Compulsory Land Acquisition and Compensation in Botswana
Authors: Lekgori Nametso , Paradza Partson , Chirisa Innocent
Published: January 2022

For years compensation has been awarded for compulsory land acquisition in Botswana and land acquisition for infrastructure projects is typically accompanied by dissatisfaction by displaced families. This is particularly the case on communal/customary land where affected parties tend to have an unclear understanding of the legal procedures that govern and inform acquisition and compensation. Often these issues of dissatisfaction relate to the misinterpretation of the legal frameworks. However, limited research has been conducted to examine the perceptions of the displaced persons and the expropriating authority as to the adequacy of the compensation payment. Therefore, it is necessary to understand how they are interpreted by each party to identify how they can be improved to better align with both parties. This paper seeks to examine the views of both the affected persons (occupying customary land) as well as the expropriating authorities (expropriating the land) in a bid to inform policy and practice, and to contribute to existing debates on compensation for expropriation. A case of the Pitsane-Tlhareseleele road project where portions of land were expropriated from customary land holders was used. Data were collected through key informant interviews and document analysis. The results of this study revealed differences between the perceptions of affected people and those of the expropriating authority. Government officials believed that the compensation offered was satisfactory, as everything was prepared in keeping with the provisions of the law. However, the affected persons were of the view that the compensation they received was not satisfactory, even though the compensation was paid in accordance with the existing statutory framework. The study concluded that this difference in perception emanates from the use of different yardsticks to measure adequacy. These differences in perception could be minimised if the existing statutes are amended to make it mandatory for the affected people to be actively involved in the property valuation process.
Serum cytokines levels in patients with myocardial infarction with non-obstructive and obstructive coronary arteries
Authors: Vorobyova D. A. , Kologrivova I. V. , Suslova T. E. , Ryabov V. V.
Published: January 2022

Aim. To compare the concentrations of proinflammatory and anti-inflammatory cytokines in patients with myocardial infarction with non-obstructive (MINOCA) and obstructive coronary arteries (MIOCA) in the early postinfarction period and after 1-year follow-up.

Material and methods. The study included 40 patients with myocardial infarction (experimental group, 19 patients; control group, 21 patients). Three (15,7%) patients with diagnosed acute myocarditis were excluded from the final analysis. Blood samples were taken upon admission, on the 2nd, 4th and 7th days from hospitalization, and also after 1-year follow-up. Twenty-three parameters were analyzed using multiplex analysis and the Multiplex Instrument FLEXMAP 3D system (Luminex Corporation), as well as the MILLIPLEX map Human Cytokine/ Chemokine Panel II.

Results. According to multiplex analysis of blood serum of the studied groups, a comparable increase in proinflammatory cytokines CCL-15, CCL-26, CCL-27 in the early postinfarction period and after 1-year follow-up, as well as antiinflammatory and regenerative cytokines CXCL-12, TPO in the early postinfarction period and after 1-year follow-up. In patients with MINOCA, higher concentrations of the following proinflammatory cytokines were determined: IL-16 upon admission (p=0,03), IL-20 on days 2 and 4 of the early postinfarction period (p=0,005 and p = 0.03), as well as CCL-15 on days 4 and 7 (p=0,05 and p=0,02). After 1-year follow-up, among the proinflammatory cytokines, a greater increase in CCL-21 (p=0,02) was noted in the patients of experimental group. Also, in patients with MINOCA, a greater increase in TPO was determined upon admission and on the 2nd day (p=0,02 and p=0,02), SCF — on the 7th day and after 1-year follow-up (p=0,04 and p=0,04), and LIF on the 4th day of early postinfarction period (p=0,007). In contrast, MIOCA patients showed a greater increase in CXCL-12 levels upon admission (p=0,04). At the same time, patients with MINOCA showed a higher level of C-reactive protein on the 1st day, as well as a higher relative monocyte count after 1-year follow-up.

Conclusion. Despite a comparable increase in the cytokines CCL-8, CCL-13, CCL26, CCL-27 in patients of both groups, in patients with MINOCA there was a greater increase in proinflammatory cytokines IL-16, IL-20, CCL-15, CCL-21, and also CXCL-12, LIF, TPO, SCF, which have anti-inflammatory and regenerative activity. After 1 year follow-up, MINOCA patients showed a significant increase in CCL-21 and SCF, with a comparable increase in other proinflammatory cytokines in patients of both groups. A greater increase in proinflammatory cytokines in patients with MINOCA may indicate a more aggressive atherosclerosis course and lead to plaque destabilization followed by ischemic event.
2020 Clinical practice guidelines for Pulmonary hypertension, including chronic thromboembolic pulmonary hypertension
Authors: Avdeev S. N. , Barbarash O. L. , Bautin A. E. , Volkov A. V. , Veselova T. N. , Galyavich A. S. , Goncharova N. S. , Gorbachevsky S. V. , Danilov N. M. , Eremenko A. A. , Martynyuk T. V. , Moiseeva O. M. , Saidova M. A. , Sergienko V. B. , Simakova M. A. , Stukalova O. V. , Chazova I. E. , Chernyavsky A. M. , Shalaev S. V. , Shmalts A. A. , Tsareva N. A.
Published: January 2022

Russian Society of Cardiology (RSC)

With the participation: Association of Cardiovascular Surgeons of Russia, Russian Respiratory Society, Federation of Anesthesiologists and Resuscitators, Association of Rheumatologists of Russia, National Congress of Radiation Diagnosticians.
Influence of characteristics of epicardial adipose tissue and myocardial sympathetic innervation on the development of late recurrence of atrial fibrillation after radiofrequency ablation
Authors: Varlamova Yu. V. , Sazonova S. I. , Popov E. V. , Batalov R. E. , Moskovskikh T. V. , Popov S. V. , Minin S. M. , Romanov A. B.
Published: January 2022

Aim. To investigate the relationship between radiological characteristics of epicardial adipose tissue (EAT) and myocardial sympathetic activity, as well as to study their association with late recurrence of atrial fibrillation (AF) after radiofrequency ablation (RFA).

Material and methods. This prospective study included 26 people with persistent and long-standing persistent AF scheduled for interventional AF treatment. Before the RFA procedure, all patients underwent cardiac 123I-metaiodobenzylguanidine (123I-MIBG) scintigraphy to assess the myocardial sympathetic innervation and contrast-enhanced cardiac multislice computed tomography to assess pulmonary vein anatomy, left atrial volume, and EAT volume. Clinical follow-up, including 12-lead electrocardiography (ECG) and 24-hour ECG monitoring, was carried out 3, 6 and 12 months after RFA.

Results. After the end of follow-up, the patients were divided into two groups: with AF recurrence (group 1, n=8) and without AF recurrence (group 2, n=18). Multivariate logistic analysis found that only the 123I-MIBG washout rate (odds ratio, 1,0943; 95% confidence interval, 1,0138-1,1812) proved to be an independent predictor of late AF recurrence after RFA. ROC analysis revealed that a 123I-MIBG washout rate >21% with a sensitivity of 75% and a specificity of 83,3% (AUC=0,844; p<0,001) predicts late AF recurrence after RFA.

Conclusion. Parameters of myocardial sympathetic activity, assessed by 123I-MIBG myocardial scintigraphy, are associated with late AF recurrence after RFA in patients with persistent and long-standing persistent AF. There were no reliable data confirming associations between myocardial sympathetic innervation and radiological EAT indicators, as well as the effect of the latter on the risk of AF recurrence after RFA.
Effect of dapagliflozin therapy on achieving cardiovascular mortality target indicators in patients with heart failure
Authors: Zhuravleva M. V. , Tereshchenko S. N. , Zhirov I. V. , Villevalde S. V. , Marin T. V. , Gagarina Yu. V.
Published: January 2022

Aim. To assess the effect of therapy with sodium glucose co-transporter type 2 inhibitor dapagliflozin in patients with heart failure with reduced ejection fraction (CHrEF) on the state cardiovascular mortality target indicators.

Material and methods. All adult Russian patients with NYHA class II-IV HFrEF (left ventricular ejection fraction ≤40%) were considered as the target population. The characteristics of patients in the study corresponded to those in the Russian Hospital HF Registry (RUS-HFR). The study suggests that the use of dapagliflozin in addition to standard therapy will be expanded by 10% of the patient population annually in 2022-24. Cardiovascular mortality modeling was performed based on the extrapolation of DAPA-HF study result. The number of deaths that can be prevented was calculated when using dapagliflozin in addition to standard therapy. Further, the contribution of prevented deaths with dapagliflozin therapy to the achievement of federal and regional cardiovascular mortality target indicators (1, 2 and 3 years) was calculated.

Results. The use of dapagliflozin in addition to standard therapy for patients with NYHA class II-IV CHrEF with the expansion of dapagliflozin therapy by 10% of the patient population annually will additionally prevent 1729 cardiovascular death in the first year. This will ensure the implementation of cardiovascular mortality target indicators in Russia in 2022 by 11,8%. In the second year, 3769 cardiovascular deaths will be prevented, which will ensure the implementation of target indicators in 2023 by 17,2%. In the third year, 5465 cardiovascular deaths prevented, which will ensure the implementation of implementation of target indicators in 2024 by 18,7%.

Conclusion. The use of dapagliflozin in addition to standard therapy for patients with NYHA class II-IV CHrEF will ensure the implementation of implementation of target indicators in 2024 by 18,7%.
Comparative assessment of aortic valve stenosis using two-dimensional, three-dimensional transesophageal echocardiography, computed tomography and cardiac catheterization
Authors: Aripov M. A. , Kali A. S. , Tanaliev N. N. , Musaev A. A. , Rashbaeva G. S. , Dautov T. B.
Published: January 2022

Aim. To compare effectiveness of ultrasound, radiological and invasive methods for assessing aortic valve (AV) stenosis.

Material and methods. This study included 33 patients with AV stenosis. The mean age of the patients was 71,8±6,8 years. All patients underwent standard and three-dimensional echocardiography, computed tomography, and cardiac catheterization.

Results. According to two-dimensional echocardiography, the AV area averaged 0,58±0,21 mm2, according to cardiac catheterization — 0,61±0,17 mm2, according to three-dimensional transesophageal echocardiography — 1,13±0,42 mm2, and according to multislice computed tomography 0,88±0,48 mm2. The difference between the values was significant (p<0,05).

Conclusion. For routine diagnosis of AV stenosis, two-dimensional echocardiography is the optimal research method. With indications for radical treatment methods, three-dimensional echocardiography or multislice computed tomography should be performed.
Theorising sexual harassment and criminalisation in a Swedish context
Authors: Wegerstad Linnea
Published: January 2022

This article offers a theoretical approach to criminalisation in relation to sexual harassment, using Sweden as example. The topic is spurred by two separate but interrelated phenomena. The first is the #metoo movement, which raised not only awareness of the widespread problem of sexual harassment, but also questions as to whether criminal law can provide a proper response. The second is a growing concern, both in international research and among Swedish activists, that the feminist struggle against sexual violence is turning towards punitive measures. Taking the standpoint that feminist research and activism should engage in a critical conversation with criminal law and crime policy, this article employs Kelly’s concept of the continuum of sexual violence to analyse the scope for criminal law interventions regarding men’s intimate intrusions against women. Swedish criminal regulation is used to highlight some of the challenges of designing a criminal provision that considers the individual effects as well as the cumulative and collective impacts of sexual harassment.
Evaluation of multiple rootstocks for ‘Montenegrina’ mandarin in Londrina, Paraná, Brazil
Authors: Carvalho Deived Uilian de , Neves Carmen Silvia Vieira Janeiro , Cruz Maria Aparecida da , Yada Inês Fumiko Ubukata , Leite Junior Rui Pereira , Tazima Zuleide Hissano
Published: January 2022

Abstract Most commercial orchards of mandarins in Paraná grow ‘Ponkan’ trees predominantly grafted on ‘Rangpur’ lime. The limited genetic diversity of citrus orchards for both scion and rootstock may promote pest and disease outbreaks. The late season ‘Montenegrina’ willowleaf mandarin has high potential for orchard diversification because of its higher productivity and better fruit quality. Therefore, this study assessed the agronomic performance of ‘Montenegrina’ mandarin trees grafted on multiple rootstocks under the edaphoclimatic conditions of Londrina, Paraná, Brazil. The trial was set in a randomized block design using the rootstocks of ‘Rangpur’ lime, ‘Cleopatra’ mandarin, ‘Sunki’ mandarin, ‘Swingle’ citrumelo, and ‘Fepagro C-13’ citrange replicated six times. The ‘Montenegrina’ mandarin trees were assessed for vegetative growth, yield, and fruit quality. The trees had similar size and yield, regardless of the rootstock, and low alternate bearing indices. The fruit quality parameters varied among the rootstocks between the four cropping seasons. Fruits from trees on ‘Rangpur’ and ‘Cleopatra’ exhibited the highest maturation indices, whereas those from ‘Swingle’ and ‘Fepagro C-13’ produced larger fruits with low number of seeds. In general, ‘Montenegrina’ trees can be grown on all evaluated rootstocks without incompatibility and loses in Londrina, Northern Paraná, Brazil.
Os impactos das mudanças climáticas na Segurança Alimentar e Nutricional: uma revisão da literatura
Authors: Alpino Tais de Moura Ariza , Mazoto Maíra Lopes , Barros Denise Cavalcante de , Freitas Carlos Machado de
Published: January 2022

Resumo A interface entre as Mudanças Climáticas e a Segurança Alimentar e Nutricional (SAN) tem se destacado na agenda de desenvolvimento sustentável desde o início da década de 1990. Desde então, estudos demonstram que as mudanças climáticas possuem efeitos negativos na SAN, potencializados pela pobreza e desigualdade social. O objetivo deste artigo é realizar uma revisão relacionando mudanças climáticas e SAN. A pesquisa foi realizada no PubMed utilizando os descritores “climate change and food security” no título, selecionando somente artigos em português, espanhol e inglês e com relação direta com os temas. Os principais impactos das mudanças climáticas na SAN foram no acesso, produção, qualidade nutricional e volatilidade dos preços dos alimentos. Estratégias de mitigação/adaptação aos efeitos das mudanças climáticas na SAN também foram apontadas nos estudos, além de um panorama geográfico das publicações com domínio de estudos na África e Ásia, continentes marcados por desigualdade social e pobreza. As mudanças climáticas afetam as dimensões da SAN, especialmente em populações mais pobres e em situação de desigualdade social. A relevância dos temas suscita a premência de maior investimento em políticas públicas, estudos e pesquisas acerca da temática no mundo.
Modos de autonomia em Serviços Residenciais Terapêuticos e sua relação com estratégias de desinstitucionalização
Authors: Silva Gabriela Andrade da , Cardoso Antônio José Costa , Bessoni Enrique , Peixoto Alexandre da Cunha , Rudá Caio , Silva Daniela Viana da , Branco Samuel Martins de Jesus
Published: January 2022

Resumo Serviços Residenciais Terapêuticos (SRTs) são dispositivos implantados no âmbito da Reforma Psiquiátrica brasileira para apoiar a desinstitucionalização psiquiátrica. Esta pesquisa objetivou comparar as formas de autonomia desenvolvidas por moradores de SRTs de dois municípios da Bahia, analisando sua relação com as estratégias de desinstitucionalização construídas em cada território. Participaram 19 indivíduos dos municípios referidos pelos pseudônimos Paulo Delgado (PD) e Franco Basaglia (FB). Foram realizadas visitas para observação participante e entrevistas com cinco gestores e profissionais das redes de atenção psicossocial. Registros em diários de campo e transcrições de entrevistas subsidiaram a construção de narrativas. Todos os participantes ampliaram o grau de autonomia em relação ao período em que saíram das instituições asilares. As formas de organização dos SRTs nos dois municípios produziram diferentes modos de exercer autonomia: em PD predominou a autonomia no habitar, enquanto em FB predominou a autonomia no transitar pelo território. Em ambos, a autonomia na administração de recursos financeiros foi limitada. Consideramos que as políticas públicas para desinstitucionalização foram efetivas, embora sua operacionalização possa ser aprimorada.
Fatores impulsores e restritivos da prática com grupos em serviços comunitários de atenção psicossocial
Authors: Nunes Fernanda Costa , Sousa Johnatan Martins , Pinho Eurides Santos , Caixeta Camila Cardoso , Barbosa Maria Alves , Costa António Pedro
Published: January 2022

Resumo O objetivo desta pesquisa qualitativa foi investigar as concepções teóricas dos trabalhadores sobre o grupo bem como analisar os fatores impulsores e restritivos da prática terapêutica grupal nos Centros de Atenção Psicossocial (CAPS). Participaram do estudo 66 trabalhadores de CAPS e ambulatórios da Rede de Atenção Psicossocial (RAPS) de 23 municípios do estado de Goiás. A coleta de dados se deu por meio de questionário estruturado e entrevista grupal registrada em gravação de áudio e fotografias. Da análise temática dos dados emergiram o conceito do que o grupo é e do que o grupo não é. Tanto no eixo das forças impulsoras, quanto das forças restritivas, as categorias foram organizadas em três blocos de análise: aspectos relacionados ao serviço, aos profissionais e aos usuários. Aspectos relacionais, estruturais, terapêuticos e a competência profissional para a coordenação de grupo se integram de modo antagônico, complementar e indissociável para apreensão da realidade estudada. Conclui-se que evidenciar os aspectos restritivos que precisam ser reconhecidos e aprimorados bem como os impulsores que precisam ser mantidos e potencializados pode contribuir ativamente para ampliar a capacidade terapêutica do uso da tecnologia grupal no contexto da saúde mental.
Influência da autoavaliação para melhoria do acesso e da qualidade no quantitativo de procedimentos dos Centros de Especialidades Odontológicas
Authors: Filgueiras Leonardo Vilar , Cabreira Fabiana da Silva , Hugo Fernando Neves , Celeste Roger Keller
Published: January 2022

Resumo Estudou-se a influência da Autoavaliação para Melhoria do Acesso e Qualidade (AMAQ) na produção de procedimentos especializados nos Centros de Especialidades Odontológicas (CEO). Utilizou-se dados da avaliação externa de 900 CEO do primeiro ciclo do Programa para Melhoria do Acesso e Qualidade (PMAQ/CEO) e Sistema de Informação Ambulatorial (SIA/SUS). A variável dependente foi a média mensal de procedimentos (proc/mês) dos CEO entre os três períodos: 1) outubro de 2012 a setembro de 2013; 2) outubro de 2013 a setembro de 2014; e 3) outubro de 2014 a setembro 2015. A principal variável independente foi o uso da AMAQ/CEO no segundo período. Tipo de CEO, média de cirurgiões-dentistas com carga-horária de 20h, estratégias contra absenteísmo, apoio matricial, protocolos clínicos e cobertura de cadastrados na Estratégia de Saúde Bucal das Família foram covariáveis. Utilizou-se modelos de regressão linear múltipla para análises ajustadas. Equipes que utilizaram a AMAQ-CEO apresentaram média de 515,0 proc/mês, 575,5 proc/mês, e 519,9 proc/mês no primeiro, segundo e terceiro períodos, respectivamente. As equipes que utilizaram AMAQ-CEO tiveram uma maior média de produção do que aquelas que não utilizaram, com diferença ajustada de 32,7 proc/mês, 64,7 proc/mês e 27,7 proc/mês no primeiro, segundo e terceiro períodos, respectivamente.
As disputas em torno da definição do modelo de justiça juvenil do Estatuto da Criança e do Adolescente
Authors: Cifali Ana Claudia
Published: January 2022

Resumo No presente artigo, busca-se analisar um processo concreto: as disputas travadas na arena política e profissional em torno da definição da justiça juvenil no Brasil ao final dos anos 1980. O questionamento que deu origem à pesquisa decorre do interesse em verificar se a aprovação do Estatuto da Criança e do Adolescente (ECA), em 1990, constitui uma ruptura em relação ao modelo anterior, previsto nos Códigos de Menores de 1927 e 1979. Isso porque, geralmente, retrata-se o ECA como uma “revolução”, uma “mudança de paradigma” em relação ao modelo anterior, ou seja, como expressão de ruptura com o momento precedente. Para isso, optamos por recuperar essa disputa, buscando captar os modos de pensar ou racionalidades sobre a justiça juvenil, as representações sociais sobre jovens e criminalidade e os atores envolvidos nesse processo, especialmente a partir de entrevistas e discursos parlamentares. Com isso, concluímos que as disposições no ECA sobre justiça juvenil são resultado das disputas travadas no campo jurídico por aqueles identificados como “garantistas” e “menoristas” e que, apesar de trazerem inovações no sentido de impor limitações à intervenção estatal, ainda apresentam continuidades com relação ao modelo anterior.
Veterinary sanitary assessment of mutton after application of antihelminth feed additive with albendazole
Authors: Aitpayeva Z. , Tagayev O. , Smagulov D. , Sidikhov B. , Barakhov B.
Published: January 2022

Abstract This study assessed the anthelminthic feed additive albendazole effect on the main indicators of the quality of sheep meat obtained from infected and deworming animals. A total of 20 heads of Akzhaik meat and wool sheep (i.e. 2 years of age, of different sex) were used in a 20-day experiment and 2 groups of 10 heads were formed (n = 4). The sheep were fed with the basic diet (i.e. control, group CON), without adding anything, and the second group was fed the basic diet orally with the addition of a dose of 1.2 g / head (an experimental group). At the end of the experiment, a control slaughter was carried out from each group in order to study the biochemical composition of meat and its quality. The anthelmintic feed additive albendazole did not have a significant effect on the indicators (organoleptic and physicochemical) of meat quality (P> 0.04). However, the ratio of fat and ash in the meat of the control group has differences in indicators and is reduced by 24.81% and 0.03%, respectively. The drug had a significant effect on the biological value of meat in the experimental group, where there is a higher content of essential amino acids (P = 0.06), nonessential (P = 0.05) concentrations in comparison with the CON groups. The results obtained show that the meat of the experimental groups of sheep, when using the anthelminthic feed additive albendazole, did not have a significant effect on organoleptic parameters, but significantly positively influenced the metabolism, live weight gain and biological value of meat.
Sucking insects and their predators on tree canopies of a monocultural stand of Caryocar brasiliense
Authors: Demolin-Leite G. L. , Veloso R. V. S. , Azevedo A. M. , Silva J. L. , Silva L. F. , Guanabens P. F. S. , Gomes J. B. , Pereira W. R. , Silva R. S. , Zanuncio J. C.
Published: January 2022

Abstract Caryocar brasiliense Camb. (Malpighiales: Caryocaraceae) trees are widely distributed throughout the Cerrado ecosystem. The fruits of C. brasiliense trees are used by humans for food and as the main income source in many communities. C. brasiliense conservation is seriously threatened due to habitat loss caused by the land-use change. Sucking insects constitute an important ecological driver that potentially impact C. brasiliense survival in degraded environments. In addition, insects sampling methodologies for application in studies related to the conservation of C. brasiliense are poorly developed. In this study, sucking insects (Hemiptera) and their predators were recorded in three vertical strata of Caryocar brasiliense canopies. The distribution of sucking species showed vertical stratification along the canopy structure of C. brasiliense. The basal part of the canopy had the highest numbers of sucking insects Aphis gossypii (Glover 1877) (Hemiptera: Aphididae) and Bemisia tabaci (Genn. 1889) (Hemiptera: Aleyrodidae), and their predators Chrysoperla sp. (Neuroptera: Chrysopidae), spiders (Araneae), and Zelus armillatus (Lep. & Servi., 1825) (Hemiptera: Reduviidae). Predators' distribution follows the resource availability and preferred C. brasiliense tree parts with a higher abundance of prey.