bluuebunny/crossref_metadata_2025 huggingface dataset:
Going beyond the “T” in “CTC”: Social Practices as Care in Community Technology Centers
Authors: Nemer David
Published: June 2018

Community technology center (CTC) is a term usually associated with facilities that provide free or affordable computer and internet access, and sometimes training, to people in underserved communities. Despite the large number of studies done on CTCs, the literature has focused primarily on the use of ICTs as the main, if not the only, activity in these centers. When it comes to addressing social concerns, the literature has often seen them as an outcome of ICT use. It does not highlight CTCs as an inherent and important social space that helps to tackle social issues. Thus, in this study, I present an ethnographic account of how residents of favelas (urban slums in Brazil)—who are from understudied and marginalized areas—used these centers beyond the “T” (technology) in order to fulfill some of their social needs. I highlight the social practices afforded by the CTCs that were beneficial to the underserved communities. By social practices, I focus exclusively on the acts of care performed by individuals in order to address self and community needs. I argue that CTCs go beyond the use of technology and provide marginalized people with a key social space, where they alleviate some of their social concerns, such as lack of proper education, violence, drug cartel activities, and other implications of being poor.
Influence of Absorbable Calcium Sulfate-Based Bone Substitute Materials on Human Haemostasis—In Vitro Biological Behavior of Antibiotic Loaded Implants
Authors: Pförringer Dominik , Harrasser Norbert , Beirer Marc , Crönlein Moritz , Stemberger Axel , Van Griensven Martijn , Lucke Martin , Burgkart Rainer , Obermeier Andreas
Published: June 2018

Calcium sulfate (CS) formulations are frequently implanted as antibiotically impregnated bone substitutes in orthopedic and trauma surgery to prevent or treat bone infections. Calcium ions have been discussed as candidates to accelerate blood coagulation. The goal of this study is to evaluate substance-specific influences of CS formulations on blood coagulation. Specific ELISAs were conducted to determine markers of activated blood coagulation after incubation of human blood with CS beads. Additionally, wettability with freshly drawn human blood was measured. Three different types of CS bone substitute beads were compared (CS dihydrate with tripalmitin, containing Gentamicin (Herafill®-G: Group A) or Vancomycin (CaSO4-V: Group B); and a CS hemihydrate with Tobramycin (Osteoset®: Group C)). Examinations were performed by ELISA assays for F1+2, FXIIa and C3a. Our results prove that none of the CS preparations accelerated single specific assays for activated coagulation markers. This allows the conclusion that neither Herafill®-G (CaSO4-G) nor CaSO4-V alter haemostasis negatively. Blood samples incubated with Osteoset® display an elevated F1+2-activity. The addition of tripalmitin in Herafill®-G shifts the original into a significantly hydrophobic formulation. This was additionally proven by contact angle examination of the three substances with freshly drawn human blood, showing that acceleration of plasmatic coagulation is hindered by lipids and induced by surface effects caused by presence of rapidly soluble calcium ions in the Osteoset® preparation.
Effect of Alpha-Particle Irradiation on InGaP/GaAs/Ge Triple-Junction Solar Cells
Authors: Xu Jing , Guo Min , Lu Ming , He Hu , Yang Guang , Xu Jianwen
Published: June 2018

InGaP/GaAs/Ge triple-junction solar cells were irradiated with 5.1 MeV alpha particles with different fluences. The degradations of the optical and electrical properties of InGaP/GaAs/Ge solar cells were described in terms of the variation in the short-circuit current (Isc), the open-circuit voltage (Voc), the maximum power (Pmax), the spectral response (SR), and the photoluminescence (PL) versus the 5.1 MeV alpha-particle fluences. The degradation modeling of the Isc and Voc under 1 MeV, 3 MeV, and 5.1 MeV alpha-particle irradiation was performed by calculating the introduction rate of non-radiative recombination centers, and the minority-carrier capture cross section, and the results were in good agreement with experimental data. For comparison, the degradations of the Isc and Voc were presented under 1 MeV and 3 MeV proton irradiation.
Tunable Mechanical Properties of Ti-Zr-Ni-Cr-V Amorphous Ribbons via Different Melt Spinning Speeds during Rapid Solidification Process
Authors: Jiang Bing , Wang Jianxin , Xu Lingfeng , Qian Chengyuan , Liu Tiexin , Dai Jiayu , Hou Xueling
Published: June 2018

In this paper, the effects of different melt spinning speeds on the mechanical properties of (TiZr)0.5(Ni0.6Cr0.1V0.1)2.1 amorphous ribbons were studied. Tensile tests of the specimens were used to investigate mechanical behavior and mechanical properties of amorphous ribbons. The effects of cooling rate on the glass transition temperature of amorphous ribbons was discussed. The correlation between the microstructure of serrated flow behavior in stress-strain curves and melt spinning speeds of ribbons was also evaluated. In addition, when the spinning speed was 45 m/s, a large number of dense and uniform dimples appeared on the fractured surface of the specimens. Furthermore, characteristics of serrated flow behavior were obvious, which meant that Ti-Zr-Ni-Cr-V amorphous ribbons showed minor plastic behavior. It is assumed that the influence of free volume led to a serrated flow behavior of the amorphous materials, and made the amorphous material exhibit partially plastic properties. Increasing the strain rate sensitivity meant the free volume increased with the increasing spinning speed. Tensile strength (σb) and elongation (δ) of samples exhibited a dramatic increasing trend with an increase in the spinning speed. In particular, Ti-Zr-Ni-Cr-V amorphous ribbons showed better mechanical properties, namely the tensile strength of the amorphous ribbon samples significantly increased from 321 MPa at a spinning speed of 30 m/s to 675 MPa at a speed of 45 m/s. The elongation increased from 0.53% at a speed of 30 m/s to 1.29% at a speed of 45 m/s.
Experimental Study on Characteristics of Grinded Graphene Nanofluids with Surfactants
Authors: Seong HeonJin , Kim GwiNam , Jeon JongHoon , Jeong HyoMin , Noh JungPil , Kim YoungJu , Kim HyunJi , Huh SunChul
Published: June 2018

In earlier studies, much research has focused on increasing the efficiency of heat exchanger fields. Therefore, in this study, graphene nanofluid was fabricated for use as a heat transfer medium for a heat exchanger. Graphene has excellent electrical conductivity, mechanical properties, and heat transfer properties. It is expected that the heat transfer efficiency will be improved by fabricating the nanofluid. However, graphene is prone to sedimentation, because of its cohesion due to van der Waals binding force. In this experiment, a nanofluid was fabricated with enhanced dispersibility by surfactant and the ball-milling process. The zeta potential, absorbance, and thermal conductivity of the nanofluid were measured. As a result, when using the ratio of 2:1 (graphene:sodium dodecyl sulfate (SDS)), a higher thermal conductivity was obtained than in other conditions.
A Novel Atypical PKC-Iota Inhibitor, Echinochrome A, Enhances Cardiomyocyte Differentiation from Mouse Embryonic Stem Cells
Authors: Kim Hyoung , Cho Sung , Heo Hye , Jeong Seung , Kim Min , Ko Kyung , Rhee Byoung , Mishchenko Natalia , Vasileva Elena , Fedoreyev Sergey , Stonik Valentin , Han Jin
Published: June 2018

Echinochrome A (EchA) is a marine bioproduct extracted from sea urchins having antioxidant, antimicrobial, anti-inflammatory, and chelating effects, and is the active component of the clinical drug histochrome. We investigated the potential use of Ech A for inducing cardiomyocyte differentiation from mouse embryonic stem cells (mESCs). We also assessed the effects of Ech A on mitochondrial mass, inner membrane potential (Δψm), reactive oxygen species generation, and levels of Ca2+. To identify the direct target of Ech A, we performed in vitro kinase activity and surface plasmon resonance binding assays. Ech A dose-dependently enhanced cardiomyocyte differentiation with higher beating rates. Ech A (50 μM) increased the mitochondrial mass and membrane potential but did not alter the mitochondrial superoxide and Ca2+ levels. The in vitro kinase activity of the atypical protein kinase C-iota (PKCι) was significantly decreased by 50 μM of Ech A with an IC50 for PKCι activity of 107 μM. Computational protein-ligand docking simulation results suggested the direct binding of Ech A to PKCι, and surface plasmon resonance confirmed the direct binding with a low KD of 6.3 nM. Therefore, Ech A is a potential drug for enhancing cardiomyocyte differentiation from mESCs through direct binding to PKCι and inhibition of its activity.
UWB Bandpass Filter with Dual Notched Bands Using T-Shaped Resonator and L-Shaped Defected Microstrip Structure
Authors: Zheng Xuemei , Pan Yuwen , Jiang Tao
Published: June 2018

In this paper, an ultra-wideband (UWB) bandpass filter (BPF) with dual notched bands using a T-shaped resonator and L-shaped defected microstrip structure (DMS) is proposed and fabricated. First, the principle of generating notched bands by using a T-shaped resonator and L-shaped defected microstrip structure to determine the size parameters of the structure is analyzed. High frequency structure simulator (HFSS) software is used to analyze the performance of the filter, and advanced design system (ADS) is used to extract the equivalent circuit model parameters. The two simulation results are consistent, which further verifies the correctness of the circuit model. Finally, the filter is fabricated and measured. The measured results are in good agreement with simulated results, demonstrating good insertion loss and return loss. The proposed filter has dual independently controllable notched bands which are implemented by coupling the T-shaped resonator to the transmission line and by etching the L-shaped defected microstrip structure respectively. The proposed filter can suppress dispensable bands at 3.5 GHz and 7.5 GHz in WiMAX band and X-band to improve the performance of the ultra-wideband communication system. By adjusting the parameters of the T-shaped resonator and L-shaped defected microstrip structure, the UWB bandpass filter with dual notched bands working at WiMAX band and X-band can be designed and applied to the wireless communication system.
Trapping para-Quinone Methide Intermediates with Ferrocene: Synthesis and Preliminary Biological Evaluation of New Phenol-Ferrocene Conjugates
Authors: González-Pelayo Silvia , López Enol , Borge Javier , De-los-Santos-Álvarez Noemí , López Luis A.
Published: June 2018

The reaction of para-hydroxybenzyl alcohols with ferrocene in the presence of a catalytic amount of InCl3 provided ferrocenyl phenol derivatives, an interesting class of organometallic compounds with potential applications in medicinal chemistry. This transformation exhibited a reasonable substrate scope delivering the desired products in synthetically useful yields. Evidence of involvement of a para-quinone methide intermediate in this coupling process was also provided. Preliminary biological evaluation demonstrated that some of the ferrocene derivatives available by this methodology exhibit significant cytotoxicity against several cancer cell lines with IC50 values within the range of 1.07–4.89 μM.
Molecular Discrimination of Cynanchum wilfordii and Cynanchum auriculatum by InDel Markers of Chloroplast DNA
Authors: Kim Yonguk , Choi Hakjoon , Shin Jawon , Jo Ara , Lee Kyung-Eun , Cho Seung-Sik , Hwang Yong-Pil , Choi Chulyung
Published: June 2018

The tuber of Cynanchum wilfordii (Baekshuoh Radix in Korean) is an important medicinal herb in Korea and China; however, it is difficult to differentiate C. wilfordii from a related medicinal herb, C. auriculatum (Baishouwu Radix in Chinese). We sought to develop a molecular method that could be used to distinguish between the tubers of C. wilfordii and C. auriculatum. We aligned the chloroplast genome sequences (available in the NCBI database) of the two species and identified three species-specific insertion and deletion (InDel) sites in the trnQ-psbK, rps2-rpoC2, and psaJ-rpl33 intergenic spacer (IGS) regions. To confirm the presence of these three InDels and validate their use as markers, we designed three primer pairs to amplify the trnQ-psbK, rps2-rpoC2, and psaJ-rpl33 IGS regions. Polymerase chain reaction (PCR) amplification of the trnQ-psbK IGS region yielded a 249 bp fragment for C. wilfordii, and 419 bp fragment for C. auriculatum, whereas the rps2-rpoC2 IGS primers produced a 629 bp fragment from C. wilfordii and a 282 bp fragment from C. auriculatum. In the psaJ-rpl33 IGS region, allele fragments of 342 and 360 bp in length were amplified from C. wilfordii, whereas 249 and 250 bp fragment were amplified from C. auriculatum. We propose these three InDel markers as a valuable, simple, and efficient tool for identifying these medicinal herbs and will thus reduce adulteration of these herbal materials in commercial markets.
Indium-Catalyzed Direct Conversion of Lactones into Thiolactones Using a Disilathiane as a Sulfur Source
Authors: Ogiwara Yohei , Takano Ken , Horikawa Shuhei , Sakai Norio
Published: June 2018

An indium-catalyzed reaction of lactones and a disilathiane leading to thiolactones is described. The direct synthesis of thiolactones from lactones with an appropriate sulfur source is one of the most attractive approaches in organic and pharmaceutical chemistry. In this context, we found an indium-catalyzed direct conversion of lactones into thiolactones in the presence of elemental sulfur and a hydrosilane via formation of the disilathiane in situ. On the basis of the previous reaction, the application utilizing the disilathiane as a sulfur source was performed herein for the efficient synthesis of a variety of thiolactone derivatives from lactones by an indium catalyst.
Vermicompost Supplementation Improves the Stability of Bioactive Anthocyanin and Phenolic Compounds in Clinacanthus nutans Lindau
Authors: Yusof Zuhaili , Ramasamy Sujatha , Mahmood Noor Zalina , Yaacob Jamilah Syafawati
Published: June 2018

This project studied the effect of vermicompost application on the composition of bioactive anthocyanin and phenolic compounds, and the antioxidant activity of Clinacanthus nutans. The correlation between the bioactive constituents and antioxidant capacity was also evaluated. In this project, a field study was conducted using a randomized complete block design (RCBD) with four treatment groups, including control plants (CC), plants supplied with chemical fertilizer (CF), plants supplied with vermicompost (VC), and plants supplied with mixed fertilizer (MF). The leaves of C. nutans from all treatment groups were harvested, subjected to solvent extraction, and used for quantification of total anthocyanin content (TAC), total phenolic content (TPC), and total flavonoid content (TFC). The initial antioxidant activity of the extracts was evaluated using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays, as well as after two and four weeks of storage at −20 °C and 4 °C. Data analysis showed that CC plants contained the highest TAC (2180.14 ± 338.43 µg/g dry weight) and TFC (276.25 ± 3.09 mg QE/g dry weight). On the other hand, CF plants showed the highest TPC (181.53 ± 35.58 mg GAE/g dry weight). Moreover, we found that CC plants had the highest antioxidant potential against DPPH radicals whereas MF plants showed the lowest antioxidant potential. After four weeks of extract storage at −20 °C and 4 °C, the TPC, TFC, TAC, and antioxidant potential of the extracts decreased. Extracts from VC showed the lowest percentage of total phenolic and total flavonoid loss after extract storage at −20 °C and 4 °C compared with other plant extracts. At this juncture, it could be deduced that the application of vermicompost had little effect on the expression of phenolics, flavonoids, or anthocyanin in C. nutans. However, the extract from plants treated with vermicompost (VC and MF) showed better stability compared with CC and CF after extract storage at different temperatures.
Simultaneous Quantification of Ellagitannins and Related Polyphenols in Geranium thunbergii Using Quantitative NMR
Authors: Bastian Februadi , Ito Yurie , Ogahara Erika , Ganeko Natsuki , Hatano Tsutomu , Ito Hideyuki
Published: June 2018

Compared to commonly employed liquid chromatography-based methods, quantitative nuclear magnetic resonance (qNMR) is a recently developed method for accurate quantification of natural compounds in extracts. The simultaneous quantification of ellagitannins and the related polyphenols of Geranium thunbergii were studied using qNMR after a short-term and long-term decoction. The qNMR fingerprint for quantifying ellagitannin was presented in this work. Geraniin was observed in the short-term decoction as a major component while corilagin was the major component of the long-term decoction. An aqueous acetone extract of G. thunbergii after long-term decoction was extracted with diethyl ether, ethyl acetate, and n-butanol. Corilagin was found as a major constituent in the ethyl acetate and n-butanol extracts. Furthermore, the contents of these polyphenols in G. thunbergii from six locations in Japan and three locations in China were quantified. The contents of geraniin and corilagin in G. thunbergii from Japan were higher than those from China. Our finding raised the possibility that qNMR can be effectively employed as a simple, accurate, and efficient method for quantification of ellagitannins in medicinal plants.
Ball Milling Promoted N-Heterocycles Synthesis
Authors: El-Sayed Taghreed H. , Aboelnaga Asmaa , El-Atawy Mohamed A. , Hagar Mohamed
Published: June 2018

In the last years, numerous protocols have been published using ball milling for organic synthesis. Compared to other methods such as microwave or ultrasound irradiation and ionic liquids, ball mill chemistry is an economical, and ecofriendly method in organic synthesis that is rather underrepresented in the knowledge of organic chemists. The aim of this review is to explore the advantages of the application of ball milling in synthesis of N-heterocyclic compounds.
A Comparative Study of Skeuomorphic and Flat Design from a UX Perspective
Authors: Spiliotopoulos Konstantinos , Rigou Maria , Sirmakessis Spiros
Published: June 2018

A key factor influencing the effectiveness of a user interface is the usability resulting from its design, and the overall experience generated while using it, through any kind of device. The two main design trends that prevail in the field of user interface design is skeuomorphism and flat design. Skeuomorphism was used in UI design long before flat design and it is built upon the notion of metaphors and affordances. Flat design is the main design trend used in most UIs today and, unlike skeuomorphic design, it is considered as a way to explore the digital medium without trying to reproduce the appearance of the physical world. This paper investigates how users perceive the two design approaches at the level of icon design (in terms of icon recognizability, recall and effectiveness) based on series of experiments and on data collected via a Tobii eye tracker. Moreover, the paper poses the question whether users perceive an overall flat design as more aesthetically attractive or more usable than a skeuomorphic equivalent. All tested hypotheses regarding potential effect of design approach on icon recognizability, task completion time, or number of errors were rejected but users perceived flat design as more usable. The last issue considered was how users respond to functionally equivalent flat and skeuomorphic variations of websites when given specific tasks to execute. Most tested hypotheses that website design affects task completion durations, user expected and experienced difficulty, or SUS (System Usability Scale) and meCUE questionnaires scores were rejected but there was a correlation between skeuomorphic design and increased experienced difficulty, as well as design type and SUS scores but not in both websites examined.
Electronic Transport Mechanism for Schottky Diodes Formed by Au/HVPE a-Plane GaN Templates Grown via In Situ GaN Nanodot Formation
Authors: Lee Moonsang , Vu Thi Kim Oanh , Lee Kyoung Su , Kim Eun Kyu , Park Sungsoo
Published: June 2018

We investigate the electrical characteristics of Schottky contacts for an Au/hydride vapor phase epitaxy (HVPE) a-plane GaN template grown via in situ GaN nanodot formation. Although the Schottky diodes present excellent rectifying characteristics, their Schottky barrier height and ideality factor are highly dependent upon temperature variation. The relationship between the barrier height, ideality factor, and conventional Richardson plot reveals that the Schottky diodes exhibit an inhomogeneous barrier height, attributed to the interface states between the metal and a-plane GaN film and to point defects within the a-plane GaN layers grown via in situ nanodot formation. Also, we confirm that the current transport mechanism of HVPE a-plane GaN Schottky diodes grown via in situ nanodot formation prefers a thermionic field emission model rather than a thermionic emission (TE) one, implying that Poole–Frenkel emission dominates the conduction mechanism over the entire range of measured temperatures. The deep-level transient spectroscopy (DLTS) results prove the presence of noninteracting point-defect-assisted tunneling, which plays an important role in the transport mechanism. These electrical characteristics indicate that this method possesses a great throughput advantage for various applications, compared with Schottky contact to a-plane GaN grown using other methods. We expect that HVPE a-plane GaN Schottky diodes supported by in situ nanodot formation will open further opportunities for the development of nonpolar GaN-based high-performance devices.
Gold Nanoparticle-Coated ZrO2-Nanofiber Surface as a SERS-Active Substrate for Trace Detection of Pesticide Residue
Authors: Lee Han , Liao Jiunn-Der , Sivashanmugan Kundan , Liu Bernard Haochih , Fu Wei-en , Chen Chih-Chien , Chen Guo Dung , Juang Yung-Der
Published: June 2018

Trace detection of common pesticide residue is necessary to assure safety of fruit and vegetables, given that the potential health risk to consumers is attributed to the contamination of the sources. A simple, rapid and effective means of finding the residue is however required for household purposes. In recent years, the technique in association with surface-enhanced Raman scattering (SERS) has been well developed in particular for trace detection of target molecules. Herein, gold nanoparticles (Au NPs) were integrated with sol-gel spin-coated Zirconia nanofibers (ZrO2 NFs) as a chemically stable substrate and used for SERS application. The morphologies of Au NPs/ZrO2 NFs were adjusted by the precursor concentrations (_X, X = 0.05–0.5 M) and the effect of SERS on Au NPs/ZrO2 NFs_X was evaluated by different Raman laser wavelengths using rhodamine 6G as the probe molecule at low concentrations. The target pesticides, phosmet (P1), carbaryl (C1), permethrin (P2) and cypermethrin (C2) were thereafter tested and analyzed. Au NPs/ZrO2 NFs_0.3 exhibited an enhancement factor of 2.1 × 107, which could detect P1, C1, P2 and C2 at the concentrations down to 10−8, 10−7, 10−7 and 10−6 M, respectively. High selectivity to the organophosphates was also found. As the pesticides were dip-coated on an apple and then measured on the diluted juice containing sliced apple peels, the characteristic peaks of each pesticide could be clearly identified. It is thus promising to use NPs/ZrO2 NFs_0.3 as a novel SERS-active substrate for trace detection of pesticide residue upon, for example, fruits or vegetables.
Mastication of Nuts under Realistic Eating Conditions: Implications for Energy Balance
Authors: McArthur Breanna , Considine Robert , Mattes Richard
Published: June 2018

The low digestibility and high satiety effects of nuts have been partly attributed to mastication. This work examines chewing forces and the bolus particle size of nuts (walnuts, almonds, pistachios) varying in physical properties under different conditions (with and without water, juice, sweetened yogurt and plain yogurt) along with satiety sensations and gut hormone concentrations following walnut consumption (whole or butter). In a randomized, cross-over design with 50 adults (25 males, 25 females; Body Mass Index (BMI) 24.7 ± 3.4 kg/m2; age: 18–52 years old (y/o), the chewing forces and particle size distribution of chewed nuts were measured under different chewing conditions. Appetite sensations were measured at regular intervals for 3 h after nut intake, and plasma samples were collected for the measurement of glucose, insulin and Glucagon-like peptide-1 (GLP-1). The three nuts displayed different particle sizes at swallowing though no differences in chewing forces were observed. Walnuts with yogurt yielded larger particle sizes than the other treatments. Particle size was not correlated with either food palatability or flavor. Fullness sensations were higher after whole nut than nut butter consumption though there were no significant changes in glucose, insulin, or GLP-1 concentrations under any condition. Changing the conditions at swallowing might influence the release of energy from nuts.
Foods and Supplements Associated with Vitamin B12 Biomarkers among Vegetarian and Non-Vegetarian Participants of the Adventist Health Study-2 (AHS-2) Calibration Study
Authors: Damayanti Didit , Jaceldo-Siegl Karen , Beeson W. Lawrence , Fraser Gary , Oda Keiji , Haddad Ella H.
Published: June 2018

To investigate the association between plasma concentration of vitamin B12 and B12 intake from supplements, fortified foods, and animal source foods among vegetarians and non-vegetarians, we conducted a cross-sectional analysis among 728 participants of the Adventist Health Study 2 (AHS-2) calibration study. The median age of participants was 58 years, 65.4% were female, and 50.3% were White. We used six 24 h dietary recalls to measure B12 intake, serum vitamin B12, and holotranscobalamin (holoTC) concentration. B12 supplements had a significantly positive association with plasma B12 among all subjects (p trend < 0.001), especially among vegans and lacto-ovo vegetarians (p trend < 0.001). Among non-users of B12 supplements, B12 intake from milk substitutes was significantly positively associated with holoTC (p trend < 0.004) and serum B12 (p trend < 0.030). In non-vegetarians, holoTC was significantly positively associated with B12 intake from eggs, while serum B12 was significantly positively associated with B12 intake from milk in the upper tertile compared to the lower, and B12 intake from meat in the middle compared to the lower tertile intake (p < 0.011). Supplements containing B12 followed by B12 intake from milk substitutes were significant contributors of plasma vitamin B12 concentration.
Twin Screw Granulation: Effects of Properties of Primary Powders
Authors: Lute Sushma , Dhenge Ranjit , Salman Agba
Published: June 2018

Lactose and mannitol are some of the most commonly used powders in the pharmaceutical industry. The limited research published so far highlights the effects of process and formulation parameters on the properties of the granules and the tablets produced using these two types of powders separately. However, the comparison of the performance of these two types of powders during twin screw wet granulation has received no attention. The present research is focused on understanding the granulation mechanism of different grades of two pharmaceutical powders with varying properties (i.e., primary particle size, structure, and compressibility). Three grades each of lactose and mannitol were granulated at varying liquid to solid ratios (L/S) and screw speed. It was noticed that primary powder morphology plays an important role in determining the granule size and structure, and tablet tensile strength. It was indicated that the processed powders such as spray-dried and granulated lactose and mannitol can be used in formulation for wet granulation where flowability of active pharmaceutical ingredient (API) is poor.
Enduring and Stable Surface Dielectric Barrier Discharge (SDBD) Plasma Using Fluorinated Multi-Layered Polyimide
Authors: Bian Dongliang , Wu Yun
Published: June 2018

In this work, multi-layered polyimide (PI) films were surface fluorinated at 328 K and 0.05 MPa using F2/N2 mixture with 20% F2 by volume, for a fluorination time of 0, 30 and 60 min, respectively. Then, they were subjected to discharge plasma as barrier dielectrics of surface dielectric barrier discharge (SDBD) at ambient atmospheric air. The dielectric lifetime of SDBD greatly extends after 60 min surface fluorination. In addition, optical emission spectroscopy (OES) results indicate that during the plasma processing, SDBD with fluorinated PI can obtain more stable plasma parameters, including gas temperature and electron temperature. Dielectric surface properties were further evaluated by infrared thermography, scanning electron microscope (SEM), and X-ray photoelectron spectroscopy (XPS). It is considered that both physical and chemical effects lead to the extension of dielectric lifetime. The physical effect is reflected in low surface temperature and increased surface roughness, while the chemical effect is reflected in the graft of fluorine groups.
Electrospun PVA Polymer Embedded with Ceria Nanoparticles as Silicon Solar Cells Rear Surface Coaters for Efficiency Improvement
Authors: Samir Effat , Salah Mohamed , Hajjiah Ali , Shehata Nader , Fathy Marwa , Hamed Aya
Published: June 2018

This paper introduces electrospun nanofibers embedded with ceria nanoparticles as silicon solar cells coaters, showing their influence on the solar cells efficiency. Ceria nanoparticles can be synthesized to have formed oxygen vacancies (O-vacancies), which are associated with converting cerium ions from the Ce4+ state ions to the Ce3+ ones. These O-vacancies follow the rule of improving silicon solar cellconductivity through the hopping mechanism. Besides, under violet excitation, the reduced trivalent cerium Ce3+ ions are directly responsible for down-converting the un-absorbed violet or ultra-violet (UV) wavelengths to a resulted green fluorescence emission at ~520 nm. These are absorbed through the silicon solar cells active layer. When electrospun Poly(vinyl alcohol) (PVA) is embedded with ceria nanoparticles on the rear surface of silicon solar cell, a promising enhancement in the behavior of solar cells current–voltage (I–V) curve is observed. The efficiency has improved by about 24% of its initial value due to the mutual impact of improving both electrical conductivity and optical conversions from the higher surface-to-volume ratio of electrospun nanofibers embedded by ceria nanoparticles. The solar cell efficiency improvement is due to the mutual impact of both optical down-conversion and better electric paths via the used nanocomposite. The added nanostructures coating can utilize part of the transmitted UV or violet spectrum through the cell as optical conversion from violet to the visible region. In addition, the formed active tri-valent states are associated with O-vacancies which can help in a better conductivity of the generated photoelectrons from the cell through the hopping mechanism. The PVA nanofibers host offers a better distribution of ceria nanoparticles and better conductivity paths for the photoelectrons based on the better surface-to-volume ratio of the nanofibers.
Highly Graphitized Carbon Coating on SiO with a π–π Stacking Precursor Polymer for High Performance Lithium-Ion Batteries
Authors: Fang Shan , Li Ning , Zheng Tianyue , Fu Yanbao , Song Xiangyun , Zhang Ting , Li Shaopeng , Wang Bin , Zhang Xiaogang , Liu Gao
Published: June 2018

A highly graphitized carbon on a silicon monoxide (SiO) surface coating at low temperature, based on polymer precursor π–π stacking, was developed. A novel conductive and electrochemically stable carbon coating was rationally designed to modify the SiO anode materials by controlling the sintering of a conductive polymer, a pyrene-based homopolymer poly (1-pyrenemethyl methacrylate; PPy), which achieved high graphitization of the carbon layers at a low temperature and avoided silicon carbide formation and possible SiO material transformation. When evaluated as the anode of a lithium-ion battery (LIB), the carbon-coated SiO composite delivered a high discharge capacity of 2058.6 mAh/g at 0.05 C of the first formation cycle with an initial Coulombic efficiency (ICE) of 62.2%. After 50 cycles at 0.1 C, this electrode capacity was 1090.2 mAh/g (~82% capacity retention, relative to the capacity of the second cycle at 0.1 °C rate), and a specific capacity of 514.7 mAh/g was attained at 0.3 C after 500 cycles. Furthermore, the coin-type full cell composed of the carbon coated SiO composite anode and the Li[Ni0.5Co0.2Mn0.3O2] cathode attained excellent cycling performance. The results show the potential applications for using a π–π stacking polymer precursor to generate a highly graphitize coating for next-generation high-energy-density LIBs.
Revisiting the “Secret Consort” (gsang yum) in Tibetan Buddhism
Authors: Gayley Holly
Published: June 2018

This article revisits the question, first introduced by feminist scholars in the mid-1990s, about whether sexual practices within Buddhist tantra (heterosexually conceived) are empowering or exploitative to women. The purpose here is to complicate this question, given the different geographic settings and cultural contexts in which consort relationships have been embedded—from eastern Tibet to North America—and to nuance our understanding of the potential and pitfalls of sexuality in tantric contexts. To do so, I query the dynamics of secrecy and sexuality in tantric practice, examining twentieth century examples of female practitioners of Tibetan Buddhism who have participated in such relationships and thereby highlighting the localized ways that the “secret consort” (gsang yum) has been invoked as a social role. This issue is especially relevant today in light of the global #MeToo movement and recent disclosures of sexual improprieties and alleged abuse involving Tibetan teachers at the head of Buddhist communities in Europe and North America. For this reason, to conclude, I discuss shifting perspectives on sexuality as Buddhist tantra has spread beyond Asia and draw attention to current voices calling for greater transparency and community accountability.
Does Religion/Spirituality Modify the Association of Stressful Life Events and Suicidal Ideation in Australian Men?
Authors: Krysinska Karolina , Spittal Matthew , Pirkis Jane , Currier Dianne
Published: June 2018

In a large population cohort of Australian men, we previously observed that stressful life events were associated with increased suicidal ideation (SI). Many stressful life events, such as relationship breakdown and financial difficulties, occur frequently, yet most men who experience them do not have suicidal thoughts. There is some evidence that religious belief may be protective against suicidal behaviour. This study examined if attendance of religious service and/or perceived importance of religion/spirituality to participants modifies the association between stressful life events and suicidal thinking. Our analysis included 10,588 men who were aged 18 years or older who participated in the Australian Longitudinal Study on Male Health (Ten to Men), a national cohort study of Australian males. The study compared demographic, protective and risk factors for four subgroups: No SI, Remitted SI, New SI, and Chronic SI between Wave 1 (October 2013 to July 2014) and Wave 2 (November 2015 to May 2016) of the study and conducted logistic regression for these four outcomes. The study found a protective effect for attendance of religious services for the onset of New SI at Wave 2. Importance of religion/spirituality was positively related to Chronic SI. There were no effects of service attendance or importance for any of the other SI outcomes. We discuss results of the study in relation to social connection and broader contextual factors, such as secularization.
“Getting Along” in Parkchester: A New Era in Jewish–Irish Relations in New York City 1940–1970
Authors: Gurock Jeffrey S.
Published: June 2018

The history of conflict between New York City’s Irish Americans and east European Jews dates back to the close of the 19th century. They disputed over jobs, union memberships, housing, and frequently over politics. These conflicts crescendoed exponentially in the decade or more of the Great Depression in Gaelic neighborhoods, now more than ever, the word on the street was that the Jews were taking over. The rhetoric and organizations of Michigan-based radio preacher Father Charles Coughlin gave voice and activism to local frustrations. However, in 1940, within a new neighborhood built in the Bronx that attracted a majority of Irish and a large proportion of Jews, there was no organized anti-Semitism, no outbursts of violence, or even significant complaints that more callow Jews were being roughed up in the streets or play areas. If animosities existed, negative feelings were kept within families and were not expressed in daily youthful encounters. Why life in Parkchester was so different is the conceit of this study. Its community history from 1940–1970s constituted a turning point in their previously-contested ethnic group relationship while what went on as Jews and the Irish ‘got along’ marks off the limits of conviviality of that time.
Optimizing Lidars for Wind Turbine Control Applications—Results from the IEA Wind Task 32 Workshop
Authors: Simley Eric , Fürst Holger , Haizmann Florian , Schlipf David
Published: June 2018

IEA Wind Task 32 serves as an international platform for the research community and industry to identify and mitigate barriers to the use of lidars in wind energy applications. The workshop “Optimizing Lidar Design for Wind Energy Applications” was held in July 2016 to identify lidar system properties that are desirable for wind turbine control applications and help foster the widespread application of lidar-assisted control (LAC). One of the main barriers this workshop aimed to address is the multidisciplinary nature of LAC. Since lidar suppliers, wind turbine manufacturers, and researchers typically focus on their own areas of expertise, it is possible that current lidar systems are not optimal for control purposes. This paper summarizes the results of the workshop, addressing both practical and theoretical aspects, beginning with a review of the literature on lidar optimization for control applications. Next, barriers to the use of lidar for wind turbine control are identified, such as availability and reliability concerns, followed by practical suggestions for mitigating those barriers. From a theoretical perspective, the optimization of lidar scan patterns by minimizing the error between the measurements and the rotor effective wind speed of interest is discussed. Frequency domain methods for directly calculating measurement error using a stochastic wind field model are reviewed and applied to the optimization of several continuous wave and pulsed Doppler lidar scan patterns based on commercially-available systems. An overview of the design process for a lidar-assisted pitch controller for rotor speed regulation highlights design choices that can impact the usefulness of lidar measurements beyond scan pattern optimization. Finally, using measurements from an optimized scan pattern, it is shown that the rotor speed regulation achieved after optimizing the lidar-assisted control scenario via time domain simulations matches the performance predicted by the theoretical frequency domain model.
Pitfall of the Strongest Cells in Static Random Access Memory Physical Unclonable Functions
Authors: Gong Mingyang , Liu Hailong , Min Run , Liu Zhenglin
Published: June 2018

Static Random Access Memory (SRAM) Physical Unclonable Functions (PUFs) are some of the most popular PUFs that provide a highly-secured solution for secret key storage. Given that PUF responses are noisy, the key reconstruction must use error correcting code (ECC) to reduce the noise. Repetition code is widely used in resource constrained systems as it is concise and lightweight, however, research has shown that repetition codes can lead to information leakage. In this paper we found that the strongest cell distribution in a SRAM array may leak information of the responses of SRAM PUF when the repetition code is directly applied. Experimentally, on an ASIC platform with the HHGRACE 0.13 μm process, we recovered 8.3% of the measured response using the strongest cells revealed by the helper data, and we finally obtained a clone response 79% similar to weak response using the public helper data. We therefore propose Error Resistant Fuzzy Extractor (ERFE), a 4-bit error tolerant fuzzy extractor, that extracts the value of the sum of the responses as a unique key and reduces the failure rate to 1.8 × 10−8 with 256 bit entropy.
Spatio-Temporal Field Estimation Using Kriged Kalman Filter (KKF) with Sparsity-Enforcing Sensor Placement
Authors: Roy Venkat , Simonetto Andrea , Leus Geert
Published: June 2018

We propose a sensor placement method for spatio-temporal field estimation based on a kriged Kalman filter (KKF) using a network of static or mobile sensors. The developed framework dynamically designs the optimal constellation to place the sensors. We combine the estimation error (for the stationary as well as non-stationary component of the field) minimization problem with a sparsity-enforcing penalty to design the optimal sensor constellation in an economic manner. The developed sensor placement method can be directly used for a general class of covariance matrices (ill-conditioned or well-conditioned) modelling the spatial variability of the stationary component of the field, which acts as a correlated observation noise, while estimating the non-stationary component of the field. Finally, a KKF estimator is used to estimate the field using the measurements from the selected sensing locations. Numerical results are provided to exhibit the feasibility of the proposed dynamic sensor placement followed by the KKF estimation method.
Study of the Home-Auxiliary Robot Based on BCI
Authors: Wang Fuwang , Zhang Xiaolei , Fu Rongrong , Sun Guangbin
Published: June 2018

A home-auxiliary robot platform is developed in the current study which could assist patients with physical disabilities and older persons with mobility impairments. The robot, mainly controlled by brain computer interface (BCI) technology, can not only perform actions in a person’s field of vision, but also work outside the field of vision. The wavelet decomposition (WD) is used in this study to extract the δ (0~4 Hz) and θ (4~8 Hz) sub-bands of subjects’ electroencephalogram (EEG) signals. The correlation between pairs of 14 EEG channels is determined with synchronization likelihood (SL), and the brain network structure is generated. Then, the motion characteristics are analyzed using the brain network parameters clustering coefficient (C) and global efficiency (G). Meanwhile, the eye movement characteristics in the F3 and F4 channels are identified. Finally, the motion characteristics identified by brain networks and eye movement characteristics can be used to control the home-auxiliary robot platform. The experimental result shows that the accuracy rate of left and right motion recognition using this method is more than 93%. Additionally, the similarity between that autonomous return path and the real path of the home-auxiliary robot reaches up to 0.89.
A High-Sensitivity Flexible Eddy Current Array Sensor for Crack Monitoring of Welded Structures under Varying Environment
Authors: Chen Tao , He Yuting , Du Jinqiang
Published: June 2018

This paper develops a high-sensitivity flexible eddy current array (HS-FECA) sensor for crack monitoring of welded structures under varying environment. Firstly, effects of stress, temperature and crack on output signals of the traditional flexible eddy current array (FECA) sensor were investigated by experiments that show both stress and temperature have great influences on the crack monitoring performance of the sensor. A 3-D finite element model was established using Comsol AC/DC module to analyze the perturbation effects of crack on eddy currents and output signals of the sensor, which showed perturbation effect of cracks on eddy currents is reduced by the current loop when crack propagates. Then, the HS-FECA sensor was proposed to boost the sensitivity to cracks. Simulation results show that perturbation effect of cracks on eddy currents excited by the HS-FECA sensor gradually grows stronger when the crack propagates, resulting in much higher sensitivity to cracks. Experimental result further shows that the sensitivity of the new sensor is at least 19 times that of the original one. In addition, both stress and temperature variations have little effect on signals of the new sensor.
Disentangling the Contribution of Spatial Reference Frames to Executive Functioning in Healthy and Pathological Aging: An Experimental Study with Virtual Reality
Authors: Serino Silvia , Morganti Francesca , Colombo Desirée , Pedroli Elisa , Cipresso Pietro , Riva Giuseppe
Published: June 2018

A growing body of evidence pointed out that a decline in effectively using spatial reference frames for categorizing information occurs both in normal and pathological aging. Moreover, it is also known that executive deficits primarily characterize the cognitive profile of older individuals. Acknowledging this literature, the current study was aimed to specifically disentangle the contribution of the cognitive abilities related to the use of spatial reference frames to executive functioning in both healthy and pathological aging. 48 healthy elderly individuals and 52 elderly suffering from probable Alzheimer’s Disease (AD) took part in the study. We exploited the potentiality of Virtual Reality to specifically measure the abilities in retrieving and syncing between different spatial reference frames, and then we administrated different neuropsychological tests for evaluating executive functions. Our results indicated that allocentric functions contributed significantly to the planning abilities, while syncing abilities influenced the attentional ones. The findings were discussed in terms of previous literature exploring relationships between cognitive deficits in the first phase of AD.
A Linear-Quadratic Model for the Quantification of a Mixture of Two Diluted Gases with a Single Metal Oxide Sensor
Authors: Madrolle Stéphanie , Grangeat Pierre , Jutten Christian
Published: June 2018

The aim of our work is to quantify two gases (acetone and ethanol) diluted in an air buffer using only a single metal oxide (MOX) sensor. We took advantage of the low selectivity of the MOX sensor, exploiting a dual-temperature mode. Working at two temperatures of the MOX sensitive layer allowed us to obtain diversity in the measures. Two virtual sensors were created to characterize our gas mixture. We presented a linear-quadratic mixture sensing model which was closer to the experimental data. To validate this model and the experimental protocol, we inverted the system of quadratic equations to quantify a mixture of the two gases. The linear-quadratic model was compared to the bilinear model proposed in the literature. We presented an experimental evaluation on mixtures made of a few ppm of acetone and ethanol, and we obtained a precision close to the ppm. This is an important step towards medical applications, particularly in terms of diabetes, to deliver a non-invasive measure with a low-cost device.