bluuebunny/crossref_metadata_2025 huggingface dataset:
FSGS Recurrence in Adults after Renal Transplantation
Authors: Rudnicki Michael
Published: April 2016

Recurrence of focal segmental glomerulosclerosis (FSGS) in the allograft occurs in 30–50% of patients, and it is associated with poor renal allograft survival. Major risk factors for recurrence are younger age at diagnosis, rapid progression to end-stage renal disease, white race, and the loss of previous allografts due to recurrence. Recent data support the hypothesis that circulating permeability factors play a crucial role in podocyte injury and progression of FSGS. Due to lack of controlled trials, the management of recurrent FSGS is inconsistent and highly empirical. Prophylactic and perioperative treatment with plasmapheresis and high-dose (intravenous) cyclosporine represent the main cornerstones of immunosuppressive therapy. In recent years, therapy with rituximab has shown promising results. Despite evidence of activation of the renin-angiotensin system (RAS) in recurrent FSGS and its association with progression, only limited data exist on the renoprotective role of RAS blockade in this setting. Further well designed studies are needed on pathogenesis risk factors and therapeutical options in FSGS and its recurrence after transplantation.
An Anomaly Detection Algorithm of Cloud Platform Based on Self-Organizing Maps
Authors: Liu Jun , Chen Shuyu , Zhou Zhen , Wu Tianshu
Published: April 2016

Virtual machines (VM) on a Cloud platform can be influenced by a variety of factors which can lead to decreased performance and downtime, affecting the reliability of the Cloud platform. Traditional anomaly detection algorithms and strategies for Cloud platforms have some flaws in their accuracy of detection, detection speed, and adaptability. In this paper, a dynamic and adaptive anomaly detection algorithm based on Self-Organizing Maps (SOM) for virtual machines is proposed. A unified modeling method based on SOM to detect the machine performance within the detection region is presented, which avoids the cost of modeling a single virtual machine and enhances the detection speed and reliability of large-scale virtual machines in Cloud platform. The important parameters that affect the modeling speed are optimized in the SOM process to significantly improve the accuracy of the SOM modeling and therefore the anomaly detection accuracy of the virtual machine.
A Trusted and Energy Efficient Approach for Cluster-Based Wireless Sensor Networks
Authors: Wang Tianshu , Zhang Gongxuan , Yang Xichen , Vajdi Ahmadreza
Published: April 2016

How to improve both security and energy efficiency is one of the most prominent issues in wireless sensor networks (WSNs). In this paper, we present a trusted and energy efficient approach for cluster-based WSNs. The approach offers (i) trusted hardware module design; (ii) energy-efficient clustering algorithm; and (iii) network operation. In the cluster-based WSNs, every cluster head is equipped with a designed trusted hardware module (TM) to improve security. Then, for improving the energy efficiency of the network, a trusted hardware based energy efficient clustering (TEEC) algorithm is proposed to select appropriate cluster heads. In the network operation, we use TEEC algorithm to perform clustering and apply TMs to achieve security functions. The analysis shows that our approach does well in resisting the attacks such as data confidentiality attack, data integrity attack, and compromise node attack. In addition, experimental results show that the TEEC algorithm makes more balanced clusters with the variance value of loads around 50% and prolongs the life cycle of the network at least 10% compared to traditional methods.
Acute Hepatitis after Ingestion of a Preparation of Chinese Skullcap and Black Catechu for Joint Pain
Authors: Papafragkakis Charilaos , Ona Mel A. , Reddy Madhavi , Anand Sury
Published: April 2016

Many herbal preparations are routinely used and have been occasionally associated with a wide range of side effects, from mild to severe. Chinese skullcap and black catechu are herbal medications commonly used for their hepatoprotective and other properties. We report a case of acute toxic hepatitis associated with ingestion of Chinese skullcap and black catechu in one preparation for the alleviation of joint pain.
Geometry Optimization Approaches of Inductively Coupled Printed Spiral Coils for Remote Powering of Implantable Biomedical Sensors
Authors: Mehri Sondos , Ammari Ahmed Chiheb , Ben Hadj Slama Jaleleddine , Rmili Hatem
Published: April 2016

Electronic biomedical implantable sensors need power to perform. Among the main reported approaches, inductive link is the most commonly used method for remote powering of such devices. Power efficiency is the most important characteristic to be considered when designing inductive links to transfer energy to implantable biomedical sensors. The maximum power efficiency is obtained for maximum coupling and quality factors of the coils and is generally limited as the coupling between the inductors is usually very small. This paper is dealing with geometry optimization of inductively coupled printed spiral coils for powering a given implantable sensor system. For this aim, Iterative Procedure (IP) and Genetic Algorithm (GA) analytic based optimization approaches are proposed. Both of these approaches implement simple mathematical models that approximate the coil parameters and the link efficiency values. Using numerical simulations based on Finite Element Method (FEM) and with experimental validation, the proposed analytic approaches are shown to have improved accurate performance results in comparison with the obtained performance of a reference design case. The analytical GA and IP optimization methods are also compared to a purely Finite Element Method based on numerical optimization approach (GA-FEM). Numerical and experimental validations confirmed the accuracy and the effectiveness of the analytical optimization approaches to design the optimal coil geometries for the best values of efficiency.
Ultrawideband Noise Radar Tomography: Principles, Simulation, and Experimental Validation
Authors: Shin Hee Jung , Narayanan Ram M. , Asmuth Mark A. , Rangaswamy Muralidhar
Published: April 2016

The paper introduces the principles, simulation results, and hardware implementation of ultrawideband (UWB) noise radar for obtaining tomographic images of various scenarios of rotating cylindrical objects using independent and identically distributed UWB noise waveforms. A UWB noise radar was designed to transmit multiple UWB random noise waveforms over the 3–5 GHz frequency range and to measure the backward scattering data for the validation of the theoretical analysis and numerical simulation results. The reconstructed tomographic images of the rotating cylindrical objects based on experimental results are seen to be in good agreement with the simulation results, which demonstrates the capability of UWB noise radar for complete two-dimensional tomographic image reconstruction of various shaped metallic and dielectric target objects.
Induction Effect of Bisphenol A on Gene Expression Involving Hepatic Oxidative Stress in Rat
Authors: Kazemi Sohrab , Mousavi Seydeh Narges , Aghapour Fahimeh , Rezaee Boshra , Sadeghi Farzin , Moghadamnia Ali Akbar
Published: April 2016

Background and Objective. Bisphenol A (BPA) is an abundantly used xenoestrogenic chemical which may cause various disorders in body. In the present study, we sought to investigate the effects of various doses of BPA on hepatic oxidative stress‐related gene expression in rats. Methods. Male Wistar rats weighing 150–200 g were used in this study. Three doses of the BPA (5, 25, and 125 μg/kg) in corn oil were administered as gavage during 35 consecutive days. After the experiment, the rats were expired and the livers were removed and stored at −80°C freezer for RNA extraction. Findings. The Real Time PCR showed increased expression of HO‐1 in the rats receiving BPA doses compared to the control group. This effect was dose‐dependent and higher at doses of 25 and 125 μg/kg than 5 μg/kg of body weight (p < 0.05). It was also demonstrated that various doses BPA can increase GADD45B gene expression compared to control group. That expression was significantly dominant in the lowest dose (5 μg/kg) of the BPA (p < 0.05). The final body weights (168.0 ± 10.0 gr) in the treatment group [BPA (125 μg/kg)] showed a significant decrease compared to control group (191.60 ± 6.50 gr). Conclusion. These findings demonstrate that BPA generated ROS and increased the antioxidant gene expression that causes hepatotoxicity.
Peeling Decoding of LDPC Codes with Applications in Compressed Sensing
Authors: Zeng Weijun , Wang Huali
Published: April 2016

We present a new approach for the analysis of iterative peeling decoding recovery algorithms in the context of Low-Density Parity-Check (LDPC) codes and compressed sensing. The iterative recovery algorithm is particularly interesting for its low measurement cost and low computational complexity. The asymptotic analysis can track the evolution of the fraction of unrecovered signal elements in each iteration, which is similar to the well-known density evolution analysis in the context of LDPC decoding algorithm. Our analysis shows that there exists a threshold on the density factor; if under this threshold, the recovery algorithm is successful; otherwise it will fail. Simulation results are also provided for verifying the agreement between the proposed asymptotic analysis and recovery algorithm. Compared with existing works of peeling decoding algorithm, focusing on the failure probability of the recovery algorithm, our proposed approach gives accurate evolution of performance with different parameters of measurement matrices and is easy to implement. We also show that the peeling decoding algorithm performs better than other schemes based on LDPC codes.
Laparoscopic Sleeve Gastrectomy versus Laparoscopic Banded Sleeve Gastrectomy: First Prospective Pilot Randomized Study
Authors: Tognoni Valeria , Benavoli Domenico , Bianciardi Emanuela , Perrone Federico , Ippoliti Simona , Gaspari Achille , Gentileschi Paolo
Published: April 2016

Introduction. The placement of ring or band around the gastric tube might prevent the dilation after Laparoscopic Sleeve Gastrectomy (LSG). We describe the first randomized study comparing LSG and Laparoscopic Banded Sleeve Gastrectomy (LBSG).Material and Method. Fifty obese patients were enrolled in the study between January 2014 and January 2015. We analysed differences in operative time, complication rate, mortality, and BMI between the two groups over a period of 12 months.Results. Twenty-five patients received LSG (group A) and 25 LBSG (group B). The mean preoperative BMI was47.3±6.58 kg/m2and44.95±5.85 kg/m2, respectively, in the two groups. There was no statistical relevant difference in operative time. No intraoperative complications occurred. Mean BMI registered after 3, 6, and 12 months in groups A and B, respectively, were37.86±5.72 kg/m2and37.58±6.21 kg/m2(p=0.869),33.64±6.08 kg/m2and32.03±5.24 kg/m2(p=0.325), and29.72±4.40 kg/m2and27.42±4.47 kg/m2(p=0.186); no statistical relevant difference was registered between the two groups.Conclusion. LBSG is a safe and feasible procedure. The time required for the device positioning did not influence significantly the surgical time. The results of bodyweight loss did not document any statistically significant differences among the two groups, even though LBSG group showed a mean BMI slightly lower than that of the control group.
Epigenetic Control of Macrophage Polarisation and Soluble Mediator Gene Expression during Inflammation
Authors: Kapellos Theodore S. , Iqbal Asif J.
Published: April 2016

Macrophages function as sentinel cells, which constantly monitor the host environment for infection or injury. Macrophages have been shown to exhibit a spectrum of activated phenotypes, which can often be categorised under the M1/M2 paradigm. M1 macrophages secrete proinflammatory cytokines and chemokines, such as TNF-α, IL-6, IL-12, CCL4, and CXCL10, and induce phagocytosis and oxidative dependent killing mechanisms. In contrast, M2 macrophages support wound healing and resolution of inflammation. In the past decade, interest has grown in understanding the mechanisms involved in regulating macrophage activation. In particular, epigenetic control of M1 or M2 activation states has been shown to rely on posttranslational modifications of histone proteins adjacent to inflammatory-related genes. Changes in methylation and acetylation of histones by methyltransferases, demethylases, acetyltransferases, and deacetylases can all impact how macrophage phenotypes are generated. In this review, we summarise the latest advances in the field of epigenetic regulation of macrophage polarisation to M1 or M2 states, with particular focus on the cytokine and chemokine profiles associated with these phenotypes.
Impaired Thermogenesis and a Molecular Signature for Brown Adipose Tissue inId2Null Mice
Authors: Zhou Peng , Robles-Murguia Maricela , Mathew Deepa , Duffield Giles E.
Published: April 2016

Inhibitor of DNA binding 2 (ID2) is a helix-loop-helix transcriptional repressor rhythmically expressed in many adult tissues. Our previous studies have demonstrated thatId2null mice have sex-specific elevated glucose uptake in brown adipose tissue (BAT). Here we further explored the role ofId2in the regulation of core body temperature over the circadian cycle and the impact ofId2deficiency on genes involved in insulin signaling and adipogenesis in BAT. We discovered a reduced core body temperature inId2−/− mice. Moreover, inId2−/− BAT, 30 genes includingIrs1,PPARs, andPGC-1s were identified as differentially expressed in a sex-specific pattern. These data provide valuable insights into the impact ofId2deficiency on energy homeostasis of mice in a sex-specific manner.
Yupingfeng Pulvis Regulates the Balance of T Cell Subsets in Asthma Mice
Authors: Wang Zhigang , Cai Xueting , Pang Zhonghua , Wang Dawei , Ye Juan , Su Kelei , Sun Xiaoyan , Li Jing , Cao Peng , Hu Chunping
Published: April 2016

Background. Yupingfeng Pulvis (HFBP) had played an active role in many diseases, especially respiratory tract infections. Exploring the possible prevention mechanism of HFBP may provide new ideas in clinical applications for this well‐known herbal formula. Purpose. To study the possible mechanisms of therapy effect of HFBP on asthma mice via regulating the balance of Tregs and Th17 cells. Method. The female BALB/c mice were divided into five groups: control group, model group, prednisone (5.5 mg/kg) group, and 22 g/kg HFBP and 44 g/kg HFBP groups. Ovalbumin was used to make the asthma model of mice; the drug was ig administered daily after atomization for consecutive 15 d. The mice were killed after the last administration. The paraffin‐embedded tissue sections of the lungs were stained by H&E. Tregs and Th17 cells in bronchoalveolar lavage fluid were detected by flow cytometry. IL‐4, TGF‐β, and TNF‐α in the serum were detected by ELISA assay. Results. HFBP could alleviate the inflammation in the lung tissue of mice, decrease the proportion of Th17 cells, and increase the proportion of Treg cells in bronchoalveolar lavage fluid. HFBP could decrease IL‐4 and TNF‐α level and increase TGF‐β level in blood. Conclusion. HFBP could treat the asthma through impacting the balance of Th17 cells and Treg cells as well as the levels of related inflammatory cytokines in asthma mice.
Hepatocyte Growth Factor Reduces Free Cholesterol‐Mediated Lipotoxicity in Primary Hepatocytes by Countering Oxidative Stress
Authors: Domínguez-Pérez Mayra , Nuño-Lámbarri Natalia , Clavijo-Cornejo Denise , Luna-López Armando , Souza Verónica , Bucio Leticia , Miranda Roxana U. , Muñoz Linda , Gomez-Quiroz Luis Enrique , Uribe-Carvajal Salvador , Gutiérrez-Ruiz María Concepción
Published: April 2016

Cholesterol overload in the liver has shown toxic effects by inducing the aggravation of nonalcoholic fatty liver disease to steatohepatitis and sensitizing to damage. Although the mechanism of damage is complex, it has been demonstrated that oxidative stress plays a prominent role in the process. In addition, we have proved that hepatocyte growth factor induces an antioxidant response in hepatic cells; in the present work we aimed to figure out the protective effect of this growth factor in hepatocytes overloaded with free cholesterol. Hepatocytes from mice fed with a high‐cholesterol diet were treated or not with HGF, reactive oxygen species present in cholesterol overloaded hepatocytes significantly decreased, and this effect was particularly associated with the increase in glutathione and related enzymes, such as γ‐gamma glutamyl cysteine synthetase, GSH peroxidase, and GSH‐S‐transferase. Our data clearly indicate that HGF displays an antioxidant response by inducing the glutathione‐related protection system.
Treatment Options for Class III Malocclusion in Growing Patients with Emphasis on Maxillary Protraction
Authors: Azamian Zeinab , Shirban Farinaz
Published: April 2016

It is very difficult to diagnose and treat Class III malocclusion. This type of malocclusion involves a number of cranial base and maxillary and mandibular skeletal and dental compensation components. In Class III malocclusion originating from mandibular prognathism, orthodontic treatment in growing patients is not a good choice and in most cases orthognathic surgery is recommended after the end of growth. Approximately 30–40% of Class III patients exhibit some degree of maxillary deficiency; therefore, devices can be used for maxillary protraction for orthodontic treatment in early mixed dentition. In cases in which dental components are primarily responsible for Class III malocclusion, early therapeutic intervention is recommended. An electronic search was conducted using the Medline database (Entrez PubMed), the Cochrane Collaboration Oral Health Group Database of Clinical Trials, Science Direct, and Scopus. In this review article, we described the treatment options for Class III malocclusion in growing patient with an emphasis on maxillary protraction. It seems that the most important factor for treatment of Class III malocclusion in growing patient is case selection.
Influence of Antipsychotic and Anticholinergic Loads on Cognitive Functions in Patients with Schizophrenia
Authors: Rehse Michael , Bartolovic Marina , Baum Katlehn , Richter Dagmar , Weisbrod Matthias , Roesch-Ely Daniela
Published: April 2016

Many patients with schizophrenia show cognitive impairment. There is evidence that, beyond a certain dose of antipsychotic medication, the antipsychotic daily dose (ADD) may impair cognitive performance. Parallel to their D2 receptor antagonism, many antipsychotics show a significant binding affinity to cholinergic muscarinic receptors. Pharmacological treatment with a high anticholinergic daily dose (CDD) significantly impairs attention and memory performance. To examine the relationships between individual cognitive performance and ADD and/or CDD, we conducted a retrospective record-based analysis of a sample ofn=104in patients with a diagnosis of schizophrenia, all of whom had completed a comprehensive neuropsychological test battery. To calculate the individual ADD and CDD, the medication at the time of testing was converted according to equivalence models. After extracting five principal cognitive components, we examined the impact of ADD and CDD on cognitive performance in the medicated sample and subgroups using multiple regression analysis. Finally, locally weighted scatterplot smoothing (Loess) was applied to further explore the course of cognitive performance under increasing dosage. Results showed significant negative effects of ADD on performance in tests of information processing speed and verbal memory. No effects were found for CDD. The potential neuropsychopharmacological and clinical implications are discussed.
Attenuated Oxidative Stress following Acute Exhaustive Swimming Exercise Was Accompanied with Modified Gene Expression Profiles of Apoptosis in the Skeletal Muscle of Mice
Authors: Sun Yi , Cui Di , Zhang Zhe , Zhang Tan , Shi Jun , Jin Haixiu , Ge Zhe , Ji Liu , Ding Shuzhe
Published: April 2016

Purpose. The purpose of the present study was to investigate the effect of acute exhaustive swimming exercise on apoptosis in the skeletal muscle of mice. Method. C57BL/6 mice were averagely divided into seven groups. One group was used as control (C), while the remaining six groups went through one‐time exhaustive swimming exercise and were terminated at 0 h, 2 h, 6 h, 12 h, 24 h, and 48 h upon completion of exercise. Result. ABTS was significantly lowered at 12 h and 48 h after exercise. The MDA level was significantly decreased at any time points sampled following exercise. Total SOD activity was significantly decreased at 6 h, 12 h, 24 h, and 48 h after exercise. Neither mRNA of Bax nor Bax/Bcl‐2 ratio was significantly altered by exercise. mRNA of Bcl‐2 was significantly decreased since 6 h after exercise. mRNA and protein expressions of PGC‐1α were significantly increased at different time points following exercise. Conclusion. Cellular oxidative stress level was decreased following low intensity, long duration acute exhaustive swimming exercise in mice, and the enzymatic antioxidant capacity was compromised. Apoptosis of the skeletal muscle was inhibited, which could partially be explained by the enhanced level of PGC‐1α.
Fatal Nonhepatic Hyperammonemia in ICU Setting: A Rare but Serious Complication following Bariatric Surgery
Authors: Acharya Gyanendra , Mehra Sunil , Patel Ronakkumar , Frunza-Stefan Simona , Kaur Harmanjot
Published: April 2016

Bariatric surgery is well established in reducing weight and improving the obesity-associated morbidity and mortality. Hyperammonemic encephalopathy following bariatric surgery is rare but highly fatal if not diagnosed in time and managed aggressively. Both macro- and micronutrients deficiencies play a role. A 42-year-old Hispanic female with a history of Roux-en-Y Gastric Bypass Procedure was brought to ED for progressive altered mental status. Physical exam was remarkable for drowsiness with Glasgow Coma Scale 11, ascites, and bilateral pedal edema. Labs showed elevated ammonia, low hemoglobin, low serum prealbumin, albumin, HDL, and positive toxicology. She remained obtunded despite the treatment with Narcan and flumazenil and the serum ammonia level fluctuated despite standard treatment with lactulose and rifaximin. Laboratory investigations helped to elucidate the etiology of the hyperammonemia most likely secondary to unmasking the functional deficiency of the urea cycle enzymes. Hyperammonemia in the context of normal liver function tests becomes diagnostically challenging for physicians. Severe hyperammonemia is highly fatal. Early diagnosis and aggressive treatment can alter the prognosis favorably.
Markedly Reduced Thermal Pain Perception in a Schizoaffective Patient with Tardive Dyskinesia
Authors: Potvin Stéphane , Stip Emmanuel , Marchand Serge
Published: April 2016

Several case reports have described stories of schizophrenia patients reporting no discomfort in response to several medical conditions which normally elicit pain. Comparatively, experimental studies performed on pain perception in schizophrenia have not documented hypoalgesic responses that are as frank as those reported in these clinical cases. Here, we report the case of a female patient with schizoaffective disorder, who displayed markedly reduced pain perception during an experimental heat pain paradigm. Compared to a large group of healthy volunteers that we tested in 3 previous studies using the same psychophysical procedure, the experimental temperature required to induce moderate pain was radically increased in this patient (z-score = 3.6). The patient had mild psychiatric symptoms and had insight into her symptoms. She had drug-induced dyskinetic symptoms. This case report illustrates that it is possible to observe marked reductions in pain perception in schizophrenia patients tested in experimental settings but that the phenomenon is relatively rare. Regardless of the exact nature of pain indifference in schizophrenia, it can delay diagnosis and treatment of medical problems in these patients. Future studies in the field will need to pay attention to drug-induced extrapyramidal symptoms.
Research on the Rockburst Tendency and AE Characteristics of Inhomogeneous Coal-Rock Combination Bodies
Authors: Tan Yun-liang , Guo Wei-yao , Gu Qing-heng , Zhao Tong-bin , Yu Feng-hai , Hu Shan-chao , Yin Yan-chun
Published: April 2016

In order to research the influence of homogeneity on the rockburst tendency and on AE characteristics of coal-rock combination body, uniaxial compressive tests of inhomogeneous coal-rock combination bodies obeyed by the Weibull distribution were simulated using particle flow code (PFC2D). Macromechanical properties, energy evolution law, and AE characteristics were analyzed. The results show that (1) the elastic modulus homogeneitymEhas an exponential relation with macroscopic modulusE, and the bonding strength homogeneitymσhas an exponential relation with uniaxial compressive strengthσc; (2) the rockburst tendency of the coal-rock combination body will increase with the increase ofmEormσ, andmσis the leading factor influencing this tendency; and (3) both the change law of AE hits and lasting time in different periods of AE characteristics are influenced bymσ, butmEjust influences the lasting time. The more inhomogeneous the coal-rock combination body is, the shorter the lasting time in booming period of AE characteristics will be. This phenomenon can be used to predict the rockburst tendency of the coal-rock combination body.
Magneto Binary Nanofluid Convection in Porous Medium
Authors: Sharma Jyoti , Gupta Urvashi , Wanchoo R. K.
Published: April 2016

The effect of an externally impressed magnetic field on the stability of a binary nanofluid layer in porous medium is considered in this work. The conservation equations related to the system are solved using normal mode technique and Galerkin method to analyze the problem. The complex expressions are approximated to get useful results. Mode of heat transfer is stationary for top heavy distribution of nanoparticles in the fluid layer and top heavy nanofluids are very less stable than regular fluids. Oscillatory motions are possible for bottom heavy distribution of nanoparticles and they are not much influenced by properties of different nanoparticles. A comparative analysis of the instability of water based nanofluids with metallic (Cu, Ag) and semiconducting (TiO2, SiO2) nanoparticles under the influence of magnetic field is examined. Semiconducting nanofluids are found to be more stable than metallic nanofluids. Porosity destabilizes the layer while solute difference (at the boundaries of the layer) stabilizes it. Magnetic field stabilizes the fluid layer system significantly.
Gait Planning and Stability Control of a Quadruped Robot
Authors: Li Junmin , Wang Jinge , Yang Simon X. , Zhou Kedong , Tang Huijuan
Published: April 2016

In order to realize smooth gait planning and stability control of a quadruped robot, a new controller algorithm based on CPG-ZMP (central pattern generator-zero moment point) is put forward in this paper. To generate smooth gait and shorten the adjusting time of the model oscillation system, a new CPG model controller and its gait switching strategy based on Wilson-Cowan model are presented in the paper. The control signals of knee-hip joints are obtained by the improved multi-DOF reduced order control theory. To realize stability control, the adaptive speed adjustment and gait switch are completed by the real-time computing of ZMP. Experiment results show that the quadruped robot’s gaits are efficiently generated and the gait switch is smooth in the CPG control algorithm. Meanwhile, the stability of robot’s movement is improved greatly with the CPG-ZMP algorithm. The algorithm in this paper has good practicability, which lays a foundation for the production of the robot prototype.
Commitments and Contests
Authors: Stovel Katherine , Chiang Yen-Sheng
Published: April 2016

This article offers a contribution to the broader theoretical goal of increasing our systematic understanding of the social mechanisms that underlie collective behavior. Specifically, we ask how it is possible that equity can arise in a market situation. Even though fair outcomes can be observed across a wide range of social situations that are not centrally coordinated, we argue that there is scant understanding of how these outcomes are facilitated and what impact they have on interaction patterns. We use experimental game theory to test two mechanisms of preferential association, which is defined as a situation where there is competition for partners and in which two actors have a preference for each other. The first mechanism, committed partnership, is abundant in social life and is exemplified by friendships. The second mechanism, competitive altruism, is the intuitive idea that to secure a desirable matching, one must display desirable behavior. To test the mechanisms, we use a laboratory experiment in which participants play a version of the well-known repeated Ultimatum Game. In our version of the game, players either (a) play each other randomly, (b) according to reputation, or (c) according to preferential association in which players are matched according to a preferred ranking of past player histories. The results suggest that fairness can arise from the reduced risk associated with committing to a desirable partner. This is a study of micro-to-micro mechanisms, investigating the micro-level conditions that produce a particular type of social action, namely, a sustainable equitable division of offerings.
The Neoliberal Yogi and the Politics of Yoga
Authors: Godrej Farah
Published: April 2016

Can the theory and practice of the yogic tradition serve as a challenge to dominant cultural and political norms in the Western world? In this essay I demonstrate that modern yoga is a creature of fabrication, while arguing that yogic norms can simultaneously reinforce and challenge the norms of contemporary Western neoliberal societies. In its current and most common iteration in the West, yoga practice does stand in danger of reinforcing neoliberal constructions of selfhood. However, yoga does contain ample resources for challenging neoliberal subjectivity, but this requires reading the yogic tradition in a particular way, to emphasize certain philosophical elements over others, while directing its practice toward an inward-oriented detachment from material outcomes and desires. Contemporary claims about yoga’s counterhegemonic status often rely on exaggerated notions of its former “purity” and “authenticity,” which belie its invented and retrospectively reconstructed nature. Rather than engaging in these debates about authenticity, scholars and practitioners may productively turn their energies toward enacting a resistant, anti-neoliberal practice of yoga, while remaining self-conscious about the particularity and partiality of the interpretive position on which such a practice is founded.
Invisible without scrubs
Authors: Robertson Scott
Published: April 2016

This article discusses the limitations of the current understanding of Registered Nurses (RNs) in leadership roles in Canada, particularly outside the hospital setting. Existing data and published reports on nursing workforce composition are reviewed. Two pilot projects engaging undergraduate nursing students in the practice domain of policy and administration are described.
“They are Us—We are Them”
Authors: Knaak Stephanie , Karpa Jane , Robinson Renee , Bradley Louise
Published: April 2016

Stigmatization towards persons with mental illnesses is a major quality of care concern. Unfortunately, nurses are no less implicated than other health professions. This article reports the results of an evaluation of a learning intervention for psychiatric nursing students in partnership between Brandon University and the Mental Health Commission of Canada. We describe this intervention as an example of transformational learning through nursing education leadership and suggest its use as a promising model for cultural change in healthcare practice. Leaders and managers are encouraged to explore how such a model may be adaptable or implementable for their own organizations and departments.
Nursing leadership of the transcatheter aortic valve implantation Heart Team
Authors: Lauck Sandra B. , McGladrey Janis , Lawlor Cindy , Webb John G.
Published: April 2016

Transcatheter Aortic Valve Implantation (TAVI) is an innovative and resource-intensive treatment of valvular heart disease. Growing evidence and excellent outcomes are contributing to increased patient demand. The Heart Team is foundational to TAVI programs to manage the complexities of case selection and other aspects of care. The competencies and expertise of nurses are well suited to provide administrative and clinical leadership within the TAVI Heart Team to promote efficient, effective, and sustainable program development. The contributions of nursing administrative and clinical leaders exemplify the leadership roles that nurses can assume in healthcare innovation.
The Value of Sonography in the Assessment of Skin Cancers and Their Metastases
Authors: DiGiacinto Dora , Bagley Jennifer , Goldsbury Amber M.
Published: April 2016

Skin cancer has become more prevalent in recent years, and finding ways to assess and characterize it prior to excision is important. Sonography can be an integral part of the preoperative and follow-up assessment of melanoma, metastatic lymph nodes, and nonmelanoma skin cancers. A review of the literature is reported, indicating that sonography appears to be effective at showing lesion thickness, defining lesion borders, and helping to identify whether lymph nodes are metastatic; however, it cannot differentiate among the types of skin cancer. Based on these findings, best practice scanning techniques are outlined for sonographers.
Classification of different tomato seed cultivars by multispectral visible-near infrared spectroscopy and
chemometrics
Authors: Shrestha Santosh , Deleuran Lise , Gislum René
Published: April 2016

The feasibility of rapid and non-destructive classification of five different tomato seed cultivars was investigated
by using visible and short-wave near infrared (Vis-NIR) spectra combined with chemometric approaches. Vis-NIR spectra
containing 19 different wavelengths ranging from 375 nm to 970 nm were extracted from multispectral images of tomato
seeds. Principal component analysis (PCA) was used for data exploration, while partial least squares discriminant analysis
(PLS-DA) and support vector machine discriminant analysis (SVM-DA) were used to classify the five different tomato
cultivars. The results showed very good classification accuracy for two independent test sets ranging from 94% to 100%
for all tomato cultivars irrespective of chemometric methods. The overall classification error rates were 3.2% and 0.4% for
the PLS-DA and SVM-DA calibration models, respectively. The results indicate that Vis-NIR spectra have the potential to
be used for non-destructive discrimination of tomato seed cultivars with an opportunity to integrate them into plant genetic
resource management, plant variety protection or registration programmes.
Ethnobotanical study of herbal medicine in Ranggawulung Urban Forest, Subang District, West Java, Indonesia
Authors: PUTRI LILY SURAYYA EKA , DASUMIATI DASUMIATI , KRISTIYANTO KRISTIYANTO , MARDIANSYAH MARDIANSYAH , MALIK CHAIRUL , LEUVINADRIE LAKSMANA PUTRA , MULYONO EKA ADHI
Published: April 2016

Putri LSE, Dasumiati, Kristiyanto, Mardiansyah, Malik C, Leuvinadrie LP, Mulyono EA. Biodiversitas 17: 172-176.Â Ethnobotanical study is the first time study done in Subang District, West Java, Indonesia focused in the surrounding area ofÂ Ranggawulung Urban Forest (RUF). This study is related to plants diversity in Ranggawulung urban forest which is under the management of PT. Pertamina EP Field Subang, Indonesia. The purpose of the study was to investigate and collect information from local people on the use of medicinal plants in Subang District, West Java, Indonesia. The field study was conducted from OctoberNovember 2015 in Subang District through deep personal interview and questionnaire then all information were written and documented. Based on the diversity index of Shannon-Wiener, RUF was categorized in high diversity (Hâ€™=3.64). The total number of plant species in RUF was 1655 species belonging to 179 species from 101 families and only 32 species used for traditional medicines among local peoples. The highest frequency of plant parts used were leaves (47%) and fruit (17%)Â and followed with other parts of trunk, root, tuber, latex, bark and seed. The form of decoction was the most frequently prepared and administered orally. It indicates that Skeleton-Muscular System Disorder (SMSD)Â and Endocrinal Disorder (ED) had the highest use reports which came from 19 species of plants belonging to 3 families (Moraceae, Meliaceae, and Myrtaceae) to heal diseases including diabetes and back pain/rheumatism. It can be stated that higher index of diversity in RUF did not directly affect the use of plants for traditional medicine. Socialization of herbal medicine used among local people has to be improved as there are many species of plants are available to heal many diseases surrounding Subang District.
A literature review on Study’s methodology of nursing care for Patients with schizophrenia considering their neurocognitive functions
Authors: Kurebayashi Yusuke
Published: April 2016

INTRODUCTION; Cognitive dysfunctions of schizophrenia predict daily living problems in patients, and psychiatric nurses should consider neurocognitive abilities of schizophrenic patients. However, development of nursing care considering their neurocognitive function is remains preliminary. To facilitate the development, clarifying the methodology of recent studies is required.AIM; To clarify the methodology of the study of nursing care considering neurocognitive functions of schizophrenic patients and to obtain suggestions for further studies.METHOD; Electronic databases were searched using key terms.RESULTS; Nine articles were eligible. Seven articles discussed enhancing neurocognitive functions and only investigated inpatients. The measurement methods used to determine neurocognitive functions varied among the nine articles. Some articles introduced video games or dedicated rooms, while some used structured methods as nursing intervention.DISCUSSION; Future studies are required to use methods that measure several neurocognitive domains, examine intervention efficacy in outpatients and first-episode patients and develop feasible interventional methods in clinical settings.
Relationship between burnout level and socio-democraphic variables of teachers: Ayaş, Güdül, Beypazarı, Nallıhan of sample
Authors: Başoğlu Burhan , Şekeroğlu Mustafa Önder , Altun Emrah
Published: April 2016

In this study, Maslach Burnout Inventory was used to determine the relationship between 533 teachers’ level of burnout; who work in Ayaş, Güdül, Beypazarı and Nallıhan provinces in the northern of Ankara in different positions and their socio-demographic variables. According to obtained data results; number of children, staff position and felt wealth level in desensitisation dimension and gender, education level and staff position in personal success dimension were determined as significant. It was concluded that marital status, duration of experience in job and staff position in management were not statistically significant on emotional exhaustion, desensitisation and personal success.
Vom Projekt zum Betrieb: Die Organisation einer nachhaltigen Infrastruktur für die Geisteswissenschaften DARIAH-DE
Authors: Blümm Mirjam , Schmunk Stefan , Gietz Peter , Horstmann Wolfram , Hütter Heiko
Published: April 2016

DARIAH-DE unterstützt Forschung und Lehre in den Geistes- und Kulturwissenschaften mit einer digitalen Forschungsinfrastruktur für Digital Humanities-Tools, Forschungsdaten, fachwissenschaftliche Dienste und Services. Um den dauerhaften Betrieb der Forschungsinfrastruktur gewährleisten zu können, strebt das Projekt eine Institutionalisierung mit einer geeigneten Rechtsform, einer nachhaltigen Finanzierung und entsprechenden Governance- und Organisationsstrukturen an.
Effect of sample pre-treatment on isoflavones quantification in soybean
Authors: Wójciak-Kosior Magdalena , Sowa Ireneusz , Szymczak Grażyna , Zapała Karolina , Kocjan Ryszard , Blicharski Tomasz
Published: April 2016

High performance liquid chromatography is the most common technique for analysing isoflavones in soy; however, the appropriate sample pre-treatment is required, including extraction and, often, hydrolysis. In the present work, the kinetics of extraction was investigated with regard to the number of extraction steps and their duration for the exhaustive extraction of bonded forms of isoflavones and aglycones. In addition, a systematic experimental study of hydrolysis depending on the temperature and acidity of the medium was conducted. The results showed that the assisted methods were more effective for the isolation of isoflavones. Moreover, the differences between the results obtained using ultrasound-assisted extraction (UAE), microwave-assisted extraction and pressurised liquid extraction were not statistically significant; however, the appropriate number of extraction steps and their duration for UAE were required. The investigation also revealed that, due to the varying susceptibility of glycosides on conversion to free forms and the stability of the aglycones obtained, two parallel hydrolysis procedures should be conducted to obtain the highest hydrolysis efficiency. The optimised conditions, taking into account the shortest time combined with the highest efficiency, were as follows: 4 M HCl and 60 min for genistein; 8 M HCl and 30 min for glycitein and daidzein.
Ageing of plasticized poly(lactic acid)/poly(β-hydroxybutyrate) blend films under artificial UV irradiation and under real agricultural conditions during their application as mulches‡
Authors: Mosnáčková Katarína , Šišková Alena , Janigová Ivica , Kollár Jozef , Šlosár Miroslav , Chmela Štefan , Alexy Pavol , Chodák Ivan , Bočkaj Ján , Mosnáček Jaroslav
Published: April 2016

The paper is aimed on the investigation of natural ageing of plasticized poly(lactic acid)/poly(
A Review on Radio-Over-Fiber Technology-Based Integrated (Optical/Wireless) Networks
Authors: Rajpal Shivika , Goyal Rakesh
Published: April 2016

In the present paper, radio-over-fiber (RoF) technology has been proposed, which is the integration of the optical and radio networks. With a high transmission capacity, comparatively low cost and low attenuation, optical fiber provides an ideal solution for accomplishing the interconnections. In addition, a radio system enables the significant mobility, flexibility and easy access. Therefore, the system integration can meet the increasing demands of subscribers for voice, data and multimedia services that require the access network to support high data rates at any time and any place inexpensively. RoF has the potentiality to the backbone of the wireless access network and it has gained significant momentum in the last decade as a potential last-mile access scheme. This paper gives the comprehensive review of RoF technology used in the communication system. Concept, applications, advantages and limitations of RoF technology are also discussed in this paper.
The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase
Authors: Groh Beezly S , Yan Feng , Smith Matthew D , Yu Yanbao , Chen Xian , Xiong Yue
Published: April 2016

WDTC1/Adp encodes an evolutionarily conserved suppressor of lipid accumulation. While reduced WDTC1 expression is associated with obesity in mice and humans, its cellular function is unknown. Here, we demonstrate that WDTC1 is a component of a DDB1‐CUL4‐ROC1 (CRL4) E3 ligase. Using 3T3‐L1 cell culture model of adipogenesis, we show that disrupting the interaction between WDTC1 and DDB1 leads to a loss of adipogenic suppression by WDTC1, increased triglyceride accumulation and adipogenic gene expression. We show that the CRL4WDTC1 complex promotes histone H2AK119 monoubiquitylation, thus suggesting a role for this complex in transcriptional repression during adipogenesis. Our results identify a biochemical role for WDTC1 and extend the functional range of the CRL4 complex to the suppression of fat accumulation.
miR‐10b expression in breast cancer stem cells supports self‐renewal through negative PTEN regulation and sustained AKT activation
Authors: Bahena‐Ocampo Ivan , Espinosa Magali , Ceballos‐Cancino Gisela , Lizarraga Floria , Campos‐Arroyo Denise , Schwarz Angela , Maldonado Vilma , Melendez‐Zajgla Jorge
Published: April 2016

Cancer stem cells (CSCs) are linked to metastasis. Moreover, a discrete group of miRNAs (metastamiRs) has been shown to promote metastasis. Accordingly, we propose that miRNAs that function as metastatic promoters may influence the CSC phenotype. To study this issue, we compared the expression of 353 miRNAs in CSCs enriched from breast cancer cell lines using qRT–PCR analysis. One of the most altered miRNAs was miR‐10b, which is a reported promoter of metastasis and migration. Stable overexpression of miR‐10b in MCF‐7 cells (miR‐10b‐OE cells) promoted higher self‐renewal and expression of stemness and epithelial–mesenchymal transition (EMT) markers. In agreement with these results, inhibiting miR‐10b expression using synthetic antisense RNAs resulted in a decrease in CSCs self‐renewal. Bioinformatics analyses identified several potential miR‐10b mRNA targets, including phosphatase and tensin homolog (PTEN), a key regulator of the PI3K/AKT pathway involved in metastasis, cell survival, and self‐renewal. The targeting of PTEN by miR‐10b was confirmed using a luciferase reporter, qRT–PCR, and Western blot analyses. Lower PTEN levels were observed in CSCs, and miR‐10b depletion not only increased PTEN mRNA and protein expression but also decreased the activity of AKT, a downstream PTEN target kinase. Correspondingly, PTEN knockdown increased stem cell markers, whereas AKT inhibitors compromised the self‐renewal ability of CSCs and breast cancer cell lines overexpressing miR‐10b. In conclusion, miR‐10b regulates the self‐renewal of the breast CSC phenotype by inhibiting PTEN and maintaining AKT pathway activation.