bluuebunny/crossref_metadata_2025 huggingface dataset:
Análise do tratamento e mortalidade nos casos de câncer gástrico na região Norte do Brasil entre 2019 e 2023
Authors: Souza Larissa July Gonçalves de , Conceição Weany Jeniffer Costa da , Barbosa Vanessa Vilhena , Gonçalves Leila Castro , Souza Letícia June Gonçalves de , Santos Carla Cereja dos , Souza Ana de Matos Silva de , Coelho Murilo Rafael Silva , Pantoja Beatriz Santiago , Bacelar Raissa Tereza Gonçalves
Published: August 2024

Objetivo: Relacionar índices de mortalidade por neoplasia maligna de estômago com dados de tratamento da doença na região norte em comparação ao Brasil. Métodos: Trata-se de um estudo epidemiológico descritivo, realizado a partir de dados coletados nas bases de dados “Painel-oncologia” e “Estatísticas vitais” do Departamento de Informática do Sistema Único de Saúde (DATASUS). Resultados: Há tendência de queda no número de óbitos no Brasil, porém não as custas da região norte, haja vista que ela apresenta tendência de se manter constante. Ademais, observa-se que a duração do tratamento na região norte tende a ser superior a 60 dias e no Brasil, primariamente, 30 dias, seguida de até 60 dias. Quanto ao número de pacientes tratados, nota-se que há uma tendência de crescimento no número de pacientes tratados em todas as macrorregiões brasileiras, com exceção da região norte. Conclusão: Evidenciou-se que apesar do norte não ser a macroregião com os maiores índices de mortalidade por câncer gástrico no Brasil, ele se apresenta com os piores índices de tratamento desta neoplasia, além de possuir um déficit de profissionais habilitados na área oncológica.
Assessment of practice of self-medication among the general public of Nagpur city – A cross-sectional survey
Authors: Hasan Fauzia , Kahar Anita Rama , Joshi Jayashree
Published: August 2024

Objectives:

Self-medication is the use of medication to treat self-diagnosed disorders. These are commonly known as “non-prescription” or “over-the-counter” drugs. Since there is no prescription required, the drugs used to self-medicate can be obtained at pharmacies and supermarkets. People usually self-medicate when they have minor ailments such as cough, fever, and headache.The aim of this study was to evaluate the practice of self-medication among the general public of Nagpur city and correlate it with gender, age, and education.

Material and Methods:

A cross-sectional study was conducted among the general population of Nagpur by obtaining responses to a pre-validated questionnaire issued in interest. The study population included people of age group 18 years and above. The questionnaire was circulated among the general public of Nagpur city for a period of 1 month.

Results:

A total of 321 responses were collected. It was observed that 226 of the responders from both the genders self-medicated for a minor ailment and by repeated use of old prescription.

Conclusion:

Self-medication has become a norm among the general public of Nagpur city. Self-medication is influenced by prior experience with a medical condition and its management . It is vital to inform the public of the risk of antimicrobial resistance as well as the individual risk of harmful medication reactions.
A SYSTEM OF ORGANIZATIONAL AND TECHNICAL MEASURES FOR SAFE CLOSURE OF DEEP DISPOSAL FACILITIES FOR LIQUID RADIOACTIVE WASTE.CONCEPTUAL PROVISIONS
Authors: Понизов А.В.
Published: August 2024

Проведен анализ опыта ликвидации эксплуатационных скважин на пунктах глубинного захоронения жидкихрадиоактивных отходов. Определены количественные показатели, относящиеся к ликвидации скважин на примере пункта глубинного захоронения жидких радиоактивных отходов «Димитровградский».С учетом требований федеральных норм и правил в области использования атомной энергии по обеспечению безопасности закрытия пункта глубинного захоронения жидких радиоактивных отходов сформулированы и систематизированы концептуальные положения о системе организационно-технических мер, необходимых для безопасного закрытия пункта глубинного захоронения жидких радиоактивных отходов, применительно к варианту «немедленное закрытие».

The analysis of the experience of the closure of operational boreholes of deep disposal facilities for liquid radioactive waste was performed. Quantitative criteria related to the closure of the deep disposal facilities for liquid radioactive waste “Dimitrovgrasky” boreholes were specified.Conceptual proposals to the organizational and technical measures required for the safe closure of the deep disposal facilities for liquid radioactive waste as applied to «immediate» closure option have been specified and systematized based on the federal rules and regulations in the field of atomic energy use that establish safety requirements for the closure of the deep disposal facilities for liquid radioactive waste.
OPLS5: Addition of Polarizability and Improved Treatment of Metals
Authors: Damm Wolfgang , Dajnowicz Steven , Ghoreishi Delaram , Yu Yalun , Ganeshan Karthik , Madin Owen , Rudshteyn Benjamin , Hu Rui , Wu Meng , Shang Yi , Albanese Steven , Zou Yefen , Ye Min , Johnson Zachary , Trzoss Michael , Rafi Salma , Kapilashrami Kanishk , Saleh Noureldin , Ghanakota Phani , Zhang Yan , Sampson Jared , Chen Wei , Wang Lingle , Dahlgren Markus , Russell Ellery , Leffler Abba , Abel Robert , Friesner Richard , Harder Edward
Published: August 2024

We report on the development and validation of the OPLS5 force field. OPLS5 further extends the accuracy of our previous model (OPLS4) with the addition of explicit polarization to improve model accuracy for molecular ions and cation-pi interactions. OPLS5 also includes advances to the functional form for metals achieving significant improvements across benchmarks assessing the structure and energetics of metal-organic complexes. Together these advances lead to improved accuracy on our protein-ligand binding benchmarks.
High-Throughput Automated Data Analysis workflow for ADC Biotransformation Characterization
Authors: Liu Kate , Ai Yongling , Tan Hui Yin , Yuan Jiaqi , Meissen John K. , Huang Yue , Rosenbaum Anton I.
Published: August 2024

Antibody-drug conjugates (ADCs) have garnered renewed attention after decades of research to fine-tune their components, maximizing efficacy while minimizing toxicity. Understanding structural integrity of ADCs in vivo is critical for lead optimization. Despite of its importance, currently ADC biotransformation has not been broadly studied. High resolution accurate mass data analysis of biotransformed products has been a major bottleneck because of manual and time-consuming analyte identification process which can take days to weeks of analysis time by expert users. We developed a streamlined data analysis workflow that enables automated peak identification using various commercial software tools significantly improving data processing efficiency. A linker-payload biotransformation library was created for each new molecule and then combined with antibody sequence information for peak matching. As a proof of concept, we tested this workflow across different payload and linker types: an example using a topoisomerase I inhibitor-conjugated ADC and a comparison to a historical in vivo ADC biotransformation dataset for a pyrrolobenzodiazepine-conjugated ADC. Using this automated workflow, we were able to rapidly identify major biotransformation species that were previously found manually including loss of linker-payload, maleimide ring hydrolysis, cysteinylation at deconjugated site and partial linker-payload cleavage. Overall, this improved data-analysis workflow has demonstrated its superb effectiveness in streamlining ADC biotransformation identification and enabled quantification that was highly comparable to previously obtained results, thus demonstrating its comparability. This advancement can now positively impact drug development by substantially reducing data analysis time thus enabling faster design-test-analyze cycle times which are critical in early drug discovery setting.
Application of tea leaves in the circular economy: A sustainable approach to remove synthetic dye from wastewater by alkali-activated spent tea leaves
Authors: Bhattacharya Ritwija , Ramrakhiani Lata , Mukhopadhyay Aniruddha , Bhattacharjee Pritha
Published: August 2024

Spent tea leaves (STL) were recycled and utilized to reduce water pollution caused by synthetic dyes. The current study used STL as a biosorbent to remove malachite green (MG) dye from aqueous solutions and fish aquarium wastewater. The dye removal efficiency was enhanced by alkali (NaOH) and thermal pretreatment and showed 98% removal efficiency. Biosorbent characteristics and dye removal mechanisms were established using BET-surface area, zeta-potential, SEM, and FTIR. An optimum adsorption capacity of 40.6 mgg-1 was obtained for MG. Equilibrium sorption data were analyzed by Langmuir and Freundlich isotherm. Sorption kinetics was determined by pseudo-first-order and pseudo-second-order kinetic models. Experimental data showed the best fit with Langmuir isotherm and the adsorption followed pseudo-second-order kinetics. The negative value of free energy (ΔG◦) and positive value of enthalpy (ΔH◦) changes obtained from the thermodynamic studies indicated the spontaneous and endothermic nature of the adsorption. In our previous study, the bioactive compound theaflavin was isolated from fresh black tea leaves to treat cancer. Also, the STL generated after the theaflavin extraction from the tea leaves or after the consumption of tea as a beverage can be used as a potential source of natural dye for the textile industries which could be a possible alternative to the harmful synthetic dyes. Taken together, our studies close the loop of circular economy in the application of tea leaves in therapeutics, textile industries, and waste management by reusing, recycling, and repurposing the product and its wastes through multiple generations.
THE EFFECT OF GAMIFICATION ON STUDENTS’ MOTIVATION TOWARD LEARNING ENGLISH
Authors: Saidgul Sazan , Mohammed Fakhir
Published: August 2024

The current study investigates the effect of gamification (i.e., Duolingo) on students' motivation and engagement toward learning English. Gamification incorporates game elements into non-game contexts like education to increase user engagement. By using quantitative methods for collecting the data, a questionnaire of 15 statements was utilized and distributed on 60 (12-17 years old) participants. After obtaining the data, and using Excel sheets, the results showed that most students found Duolingo easy to use for learning English. Over half felt the games were engaging and helped improve their skills, especially speaking and writing. However, some found the games ineffective or time consuming. Most students were motivated and challenged yet also needed support in using Duolingo effectively. The students preferred Duolingo over traditional methods and planned to continue using it. Generally, to know the impressions of a sample of students about using gamification for their education will be helpful for students as well as teachers to boost learning outcomes and provide more guidance on effective usage.
THE GROWTH OF NIGERIA'S ECONOMY FROM 1981 TO 2019 IN RELATION TO THE FINANCING OF AGRICULTURE
Authors: Okon Jacob Augustine
Published: August 2024

The analysis of various economic variables in Nigeria from 1981 to 2019 shows that the country’s economy has been heavily reliant on oil exports, which has left it vulnerable to external shocks and hindered economic growth. This over-reliance on oil exports has led to neglect of the agricultural sector, which was once the main source of foreign currency earnings for Nigeria. As a result, there has been a decline in food production and an increase in imports. However, a study investigating the impact of government spending on agriculture on Nigeria’s economic growth using secondary data covering the same period shows that investing in agriculture is essential for Nigeria to achieve a diversified economy and sustainable economic growth. The study uses the Ordinary Least Square (OLS) approach and the Augmented Dickey-Fuller (ADF) unit root test to analyze the data and concludes that diversifying the economy into non-oil industries, such as agriculture, is likely to have a significant impact on economic growth. The regression analysis showed that government agricultural spending has a positive impact on economic growth. The findings suggest that RGDP, AO, AL, AE, and IFR had an up-down tendency, while INT had an up-down-up trend. The skewness statistic indicates that the variables’ frequency distributions were positively skewed, while the Kurtosis statistic indicates that they were normally distributed. The unit root tests indicate that all variables were stationary at 5%. The regression analysis showed that AO had a positive association with RGDP, while AL had a negative association with it. The study also provides additional information, such as the contribution of agriculture to Nigeria’s GDP and the statistical reliability of the variables.
AN ECONOMIC ANALYSIS OF PRODUCTION AND MARKETING OF MAJOR VEGETABLES IN BHAKTAPUR DISTRICT, NEPAL
Authors: K.C Naturally , Santosh Paudel
Published: August 2024

This study was conducted to analyze the economics of production and marketing of major vegetables in Bhaktapur district of Nepal. Primary data for the household survey were collected using a semi-structured questionnaire from sixty sampled respondents, from two municipalities namely, Madhyapur thimi municipality, Suryabinayak municipality by using simple random sampling method. The methodological tools such as household survey using pre-tested survey schedule, key informant interview, focus group discussion and different secondary data sources were used to collect the information. The primary data obtained from field survey were coded, tabulated and analyzed by using Statistical Package for the Social Sciences 25.0 and Microsoft Excel. Secondary data were collected through scientific journals, articles, and publications from agricultural organizations, projects, and programs. Simple indexing method was used for ranking of problems and identifying major determinant of production and benefit cost ratio, gross margin, net margin was calculated by using formula. Average area under vegetable cultivation was found to be 4.29 ropani. The cost of production per ropani for tomato, cauliflower and radish was NRs. 71,521, NRs. 32,930 and NRs. 27,900 respectively. The BC ratio was higher for tomato (1.9) followed by radish (1.70) and cauliflower (1.64). B: C ratio of all the vegetables under study was higher than one which implies that vegetable farming in the study area is profitable farm business. The marketing margin per kg of tomato, cauliflower and radish was NRs. 31.00, NRs. 39.50 and NRs. 19.00, respectively whereas the producer’s share was found to be higher for tomato (55.71%) followed by radish (52.50%) and cauliflower (46.97%). Middlemen had major influence on pricing of vegetables. Analysis of the study showed that the major constraints in production and marketing of vegetables were incidence of disease/pest and low farm gate.
Análise espacial de gastroenterite em crianças menores de cinco anos na Paraíba, Brasil, 2010-2017
Authors: Gomes Adriana Nascimento , Soares Ricardo Sousa , Moraes Ronei Marcos de , Vianna Rodrigo Pinheiro de Toledo
Published: August 2024

A gastroenterite é uma comorbidade que afeta crianças principalmente de países pobres e em desenvolvimento, em moradias sem saneamento básico adequado e com condições de higiene precárias, além de habitarem em regiões geográficas com baixo índice pluviométrico, como é o caso da Paraíba localizada na região mais seca do Brasil, o Nordeste. Objetivo: Analisar geograficamente os aglomerados espaciais das internações por gastroenterite em crianças menores de cinco anos de idade no estado da Paraíba, de 2010 - 2017. Métodos: Trata-se de um estudo ecológico, retrospectivo de abordagem quantitativa, cujos dados utilizados para análise são referentes ao número de internações por gastroenterite nos municípios da Paraíba, correspondem ao período de 2010 a 2017. Baseado no Sistema de Informação Geográfica, foi utilizado o método de estatística Scan espacial para identificação de aglomerados significativos através simulação de Monte Carlo, também foram elaborados mapas de Razão de Incidências Espacial da população sob risco. Resultados: Foram contabilizados 3.901 casos de gastroenterite, com redução de 63,3% da taxa de incidência de 2010 (19,9) para 2017 (7,23). Os aglomerados espaciais significativos estavam dispersos na região geográfica, sendo identificadas áreas de risco no oeste, centro, norte e sudeste do Estado, com maior concentração nas mesorregiões do Sertão e do Agreste. Conclusão: A análise geográfica espacial de gastroenterite em crianças menores de cinco anos na Paraíba identificaram aglomerados espaciais persistentes em áreas de risco elevadas no Agreste e no Sertão paraibano durante todo o período analisado.
Movimentos Gravitacionais de Massa: estudo de caso em Teresina, Piauí
Authors: Fagundes Gabriel Cunha Linhares , Aquino Cláudia Maria Sabóia de , Sousa Maurício Antonio de
Published: August 2024

Os movimentos gravitacionais de massa estão associados a desastres e prejuízos que assolam diversas cidades brasileiras, diante desta problemática, a presente pesquisa apresenta como objetivo a realização de um estudo inicial acerca dos movimentos gravitacionais de massa na cidade de Teresina/Pi. A pesquisa adotou como procedimentos metodológicos a confecção e análise de mapas, realização de pesquisas bibliográficas e trabalhos de campo. A pesquisa apoiou-se na proposta de classificação para movimentos gravitacionais de massa de Augusto Filho (1992); no manual de mapeamento de perigo e risco a movimentos gravitacionais de massa do Serviço Geológico do Brasil - CPRM (2018) e, no manual de deslizamento do Serviço Geológico dos Estados Unidos – USGS (2008). Os resultados apontaram a identificação e análise de processos de queda de detritos em taludes de corte, deslizamento, rastejo e fluxo de detritos com formação de coluviões. A pesquisa constata que tais processos estiveram relacionados a prejuízos urbanos e riscos de desabamentos.
25 YEARS OF THE NATIONAL ENVIRONMENTAL EDUCATION POLICY (PNEA): A CASE STUDY ON THE IMPLEMENTATION OF FORMAL ENVIRONMENTAL EDUCATION IN THE DAILY SCHOOL LIFE OF 120 PUBLIC SCHOOL TEACHERS IN THE MUNICIPALITY OF CABO FRIO, RJ
Authors: Oliveira Filho João Gomes de , Arruda Ana Paula Serpa Nogueira de
Published: August 2024

Objective: The objective of this study is to carry out a critical analysis of the National Environmental Education Policy based on a Case Study with 120 Teachers who are in the classroom, in Public Schools of the Education Network in the Municipality of Cabo Frio, RJ, Brazil.
Theoretical Reference: There are several theories and authors who research and write about EA. Historically, it can be said that the first person studied to describe and teach about AE was Raquel Carson, in her book “Silecious Spring” where she described the problems caused by pesticides. Subsequently, there were several international meetings that gave rise to treaties and guidelines on the predatory way in which man deals with the environment in his capitalist model of production. Among the multilateral documents signed by Brazil is the EA Treaty. Currently, we have in practice the EAF resulting from philosophical understandings arising from Federal Law No. 9,795/99 “the EA law”. In contrast to the traditional EA model, our main source of analysis is the theories of “Critical EA”, aimed at building knowledge, awareness, critical cognitions and autonomy of people in relation to their interaction with environmental goods in a sustainable and sustainable way. perennial.
Method: The methodology adopted for this research comprises exploratory field research. The technique used in the research was the “Case Study”. The quantitative method was used in the analysis of data obtained from the application of the field research instrument, namely: the questionnaire. Being applied to this statistical analysis. Each proposed question generated a table and a graph where the statistical percentages of the responses of the Teachers who answered the questionnaire are presented. A quantitative and qualitative analysis of the results was then carried out.
Results and Discussion: The results obtained confirm the hypotheses raised, as they demonstrate a lack in the training of undergraduates in undergraduate courses in relation to the EA theme, as well as an incipient and ineffective practice of formal EA in the daily lives of the Teachers surveyed.
Implications of the Research: The practical and theoretical implications of this research are visible given the demonstration of a reality of the researched that is replicated throughout the education network of the researched municipality and possibly of Public School Teachers throughout the State of RJ.
Originality/Value: This study significantly contributes to enriching the theory and practice of EAF, as it portrays the current scenario of teaching practice in relation to EAF in municipal schools with actuality and truth, demonstrating the obstacles, flaws and ways to be taken to make a constitutional right effective, namely the right to EA.
Isolation and Experimental Study on Bacteriostasis of Bacillus haynesii
Authors: Liao Jiedan , Yu Mengbo , Li Jiaming , Xie Zhiheng , Gu Wanjun , Zhou Shuzhen , Ma Yi
Published: August 2024

This experiment aims to isolate and inhibit three bacteria strains to provide candidate strains for the development and application of probiotics. Using bacterial morphological identification, 16S rDNA sequence alignment, and genetic evolution analysis, three strains were identified as Bacillus haynesii, named HP01, HD02, and HK03. Through biosurfactant activity tests, C-TAB tests, hemolysis tests, and antibacterial activity analyses, the results showed that all three strains of B. haynesii exhibited significant biosurfactant activity. Additionally, the solutions of the three strains demonstrated a pronounced antibacterial effect on Staphylococcus aureus. The resistance and safety of commonly used drugs were evaluated using the tablet diffusion method and a mouse feeding test. The results indicated that the three strains were not resistant to commonly used antibacterial drugs, and the oral bacterial solution was not pathogenic and had high safety in mice. The study concluded that all three B. haynesii strains met the basic conditions for use, with B. haynesii HP01 being the most promising candidate.
A Study of Health Prescribing for Children with Tourette’s Disorders in Children’s Health Education Specialty Care Clinics
Authors: Yang Wenping , Wang Le , Wang Sha , Ma Nannan , Mei Li
Published: August 2024

Objective: This study designs and implements the health prescription of children’s health education specialized nursing clinic based on the physical and mental characteristics of children with Tourette’s syndrome. Methods: Applying the evidence-based nursing model and nursing intervention theory based on the survey research by searching China Knowledge Network, Wanfang Database and Wipro Chinese Science and Technology Journal Database, the study collected the literature on the health prescription intervention research in children’s Tourette’s disorders health education in children’s health education of specialized nursing outpatient clinic for review and combined with the specialty characteristics to formulate “Children’s Tourette’s Disorder Health Education Prescription.” Results: Tourette’s syndrome in children is a common pediatric neurological disorder, mainly manifested as involuntary, rapid and repeated muscle twitching and vocal tics, which brings serious psychological pressure and life disturbance to the affected children. Conclusion: For children with Tourette’s syndrome, healthcare professionals should give enough care and understanding to the children and their parents, provide timely and effective health education to them, help them improve their bad behavioral habits, establish correct cognitive attitudes, enhance self-confidence, improve patient compliance, reduce the frequency of recurrence, reduce the incidence of complications and promote children’s physical and mental health development.
Research on Active and Reactive Power Decoupling Control Based on VSC-HVDC
Authors: Lin Hongshan , Lei Yiming , Ning Feng
Published: August 2024

Voltage Source Converter-based High Voltage Direct Current (VSC-HVDC) transmission technology represents a groundbreaking approach in high voltage Direct Current (DC) transmission, offering numerous technical advantages and broad application prospects. However, in the d-q synchronous rotating coordinate system, the VSC-HVDC exhibits the coupling effect of active power and reactive power, so it needs to be decoupled. This paper introduces the basic principle and mathematical model of the VSC-HVDC transmission system. Through the combination of coordinate transformation and variable substitution, a feedforward decoupling control method is derived. Then the VSC-HVDC simulation model is designed, and the simulation analysis is carried out in the MATLAB environment. The simulation results demonstrate that the method effectively achieves decoupling control of active and reactive power, exhibiting superior dynamic performance and robustness. These findings validate the correctness and effectiveness of the control strategy.
СФЕРА ЗДРАВООХРАНЕНИЯ, ОКАЗЫВАЮЩАЯ УСЛУГИ ЛИЦАМ ПОЖИЛОГО ВОЗРАСТА: НЕКОТОРЫЕ РЕЗУЛЬТАТЫ РЕАЛИЗАЦИИ ПРОЕКТА «СТАРШЕЕ ПОКОЛЕНИЕ»
Authors: КОРОБКОВА ОКСАНА КОНСТАНТИНОВНА , ВОРОНИНА НАТАЛЬЯ ВЛАДИМИРОВНА
Published: August 2024

Научная статья актуальна, так как на текущем этапе развития экономика и управление сферы услуг здравоохранения характеризуется недостаточным финансовым обеспечением данной сферы и дефицитом специалистов, оказывающим услуги лицам пожилого возраста. Целью научной работы является изучение реализации проекта «Старшее поколение» организациями здравоохранения, оказывающими услуги гражданам пожилого возраста, его финансовое обеспечение. В ходе выполнения исследования были применены следующие методы: обобщение информации, общенаучные методы исследования, количественные методы статистического анализа, опрос. Основными результатами исследования являются: на основе проведенного исследования выявлены проблемные вопросы отрасли при реализации проекта «Старшее поколение» организациями здравоохранения, оказывающими услуги гражданам пожилого возраста. Проведена оценка реализации проекта «Старшее поколение» организациями здравоохранения, оказывающими услуги гражданам пожилого возраста и исследована удовлетворенность лиц, старше 60 лет, услугами здравоохранения. Составлены рекомендации по совершенствованию управления организациями здравоохранения при оказании услуг гражданам пожилого возраста. Теоретическая значимость научной работы состоит в многогранном исследовании теоретических составляющих состояния сферы здравоохранения, оказывающих услуги лицам пожилого возраста. Оценка реализации проекта «Старшее поколение» в Дальневосточном Федеральном округе в рамках управления развитием сферы услуг здравоохранения была проведена по следующим направлениям системы сбалансированных показателей: «Получатели услуг», «Внутренние бизнес-процессы», «Финансы». Составленные рекомендации по совершенствованию управления организациями здравоохранения при оказании услуг гражданам пожилого возраста дополняют имеющиеся теоретические положения и разработки в этой области исследования, позволяют сформировать научную базу развития организаций сферы здравоохранения, оказывающих услуги лицам пожилого возраста. Практическая значимость научной статьи заключается в том, что предложенные направления по развитию экономики и управления организациями сферы здравоохранения при реализации проекта «Старшее поколение» позитивно повлияют на эффективность работы отрасли, что в свою очередь увеличивает удовлетворенность получателей данных услуг, лиц пожилого возраста, их качеством и доступностью.
МЕЖРЕГИОНАЛЬНАЯ ТОРГОВЛЯ И ЕЕ ВОЗДЕЙСТВИЕ НА ВНУТРЕННЕЕ ЭКОНОМИЧЕСКОЕ РАЗВИТИЕ
Authors: ЩЕБАРОВА НАТАЛЬЯ НИКОЛАЕВНА
Published: August 2024

Развитие торговых связей в РФ является одним из приоритетов современной экономической политики. В силу сложностей, с которыми столкнулся экспортный сектор национального российского хозяйства вследствие давления международных экономических санкций, все больше фокус внимания ученых и практиков смещается в сторону внутренней межрегиональной торговли как источника социально-экономического и пространственного развития страны на основе усиления межрегиональной интеграции. Целью стимулирования межрегиональной торговли в России является формирование комфортной среды для субъектов торговли в широком смысле этой категории - как производителей товаров, так и субъектов обменной деятельности. Решение задачи импортозамещения во многом облегчается налаживанием товарообмена между регионами национального хозяйства. Имеющаяся в них товарная продукция зачастую не поступала в сферу межрегиональной торговли ввиду существования традиционных длительных внешнеэкономических связей. Ослабление последних способствовало в последнее время успешному поиску товаропроизводителей внутри страны. В результате замена импортных товаров продукцией российских производителей из других субъектов РФ способна дать мощный синергетический эффект, направленный на стабильное возобновление экономического роста. Таким образом, актуальной научной задачей является исследование генезиса экономической мысли об исторических предпосылках и подходах к категории межрегиональной торговли. Целью данной работы является обобщение трактовок межрегиональной торговли и оценка механизмов ее потенциального влияния на региональный экономический рост. Автор приходит к выводу, что понятие межрегиональной торговли можно охарактеризовать как форму экономической деятельности субъектов двух или нескольких регионов страны, включающий операции по покупке и продаже товарно-материальных ценностей, проведении работ, оказании услуг в установленных территориальных рамках экономического взаимодействия. Региональная специализация в существенной мере способствует увеличению товарооборота между регионами, что оказывает положительное влияние на экономическое развитие в масштабах всего государства.
РОЛЬ ЧЕЛОВЕЧЕСКОГО КАПИТАЛА В ИННОВАЦИОННОМ РАЗВИТИИ РЕГИОНОВ-ЛИДЕРОВ ПРИВОЛЖСКОГО ФЕДЕРАЛЬНОГО ОКРУГА
Authors: ГАРЕЕВА НАИЛЯ АЛЬФРИТОВНА , БУРМИСТРОВА ЕКАТЕРИНА АЛЕКСАНДРОВНА
Published: August 2024

Цель работы. В условиях санкций и ограничений по заимствованию технологий человеческий капитал выступает основополагающим фактором модернизации отечественной экономики, важнейшей ресурсной составляющей регионального инновационного развития. В статье рассматриваются результаты прогнозирования показателей инновационного развития Приволжского федерального округа и его регионов-лидеров: Республики Татарстан, Нижегородской области, Республики Башкортостан с помощью синергетической модели. Методологическую основу исследования составили общелогические научные методы экономических исследований: анализ, синтез, сравнение, синергетическая модель прогнозирования инновационных показателей, обобщение, описание. Информационной базой послужили материалы официальной статистики Приволжского федерального округа и его регионов-лидеров за 2019-2022 гг. Результаты работы. Выявлены основные тенденции развития инновационных показателей Приволжского федерального округа, Республики Татарстан, Нижегородской области, Республики Башкортостан до 2029 года. В частности, с помощью синергетической модели определены прогнозные показатели активности организаций, осуществляющих инновационную деятельность, нематериальных активов инновационных организаций, доли интеллектуального труда в единице инновационной продукции. Область применения. Результаты проведенного исследования могут занять важное место в системе анализа и оценки региональной конкурентоспособности. Выводы. Регулярная оценка влияния человеческого капитала на региональные инновационные показатели с помощью синергетической модели может служить важнейшей составляющей управления региональным потенциалом.
МОДЕЛИРОВАНИЕ ФИНАНСОВЫХ РЕЗУЛЬТАТОВ ИНВЕСТИЦИОННОГО ПРОЕКТА ПО РЕСТАВРАЦИИ И ПРИСПОСОБЛЕНИЮ УСАДЬБЫ А.Г. ОСОКИНА (Г. КАЗАНЬ)
Authors: ШАГИАХМЕТОВА ЭЛЬВИРА ИЛШАТОВНА , ТРОЕПОЛЬСКАЯ НАТАЛЬЯ ЕВГЕНЬЕВНА , КАРПОВА ИРИНА ВИКТОРОВНА , ХУЗИН АЗАТ АЛМАЗОВИЧ
Published: August 2024

С конца XIX – начала ХХ в. наблюдается повышение интереса к охране объектов культурного наследия. В наше время особенно остро стоят вопросы приспособления исторических зданий под современные функции. Вопросы приспособления неразрывно связаны с основной задачей реставрации любого объекта наследия – сохранением. Так как сохранение это не только ряд проектно-изыскательских и реставрационных работ, но и включение объекта культурного наследия в активную жизнь и потребности современного общества. В исследовании рассматриваются финансовые результаты инвестиционного проекта реставрации объекта культурного наследия федерального значения. В работе были использованы следующие общенаучные методы: визуальное обследование, наблюдение, измерение, описание, иные методы фиксации, составляющие комплекс натурных исследований объекта; методы экономического анализа: метод расчета сметной стоимости объектов; метод расчёта чистого дисконтированного дохода «NPV», метод расчета дисконтированного срока окупаемости, метод однопараметрического моделирования. Результаты исследования: анализ физического состояния позволил выявить утраченные элементы здания и рассчитать сметную стоимость реставрационных работ. В работе предлагается приспособление здания под представительскую функцию, для проведения выставок художников, семинаров. Горизонт планирования был выбран равным 30 годам: реставрационные работы и период эксплуатации здания. Чтобы сделать представительское здание в области искусств привлекательным как для инвесторов, так и для арендаторов, необходимо использование льготных налоговых режимов, а также софинансирование государства в размере не менее 40% стоимости реставрационных работ. В этом случае затраты инвестора окупятся до начала новых вложений, связанных с последующим капитальным ремонтом здания.
ПОНЯТИЕ И ЭКОНОМИЧЕСКАЯ СУЩНОСТЬ ТЕХНОЛОГИЧЕСКОЙ ТРАНСФОРМАЦИИ ПРОМЫШЛЕННОСТИ НА СОВРЕМЕННОМ ЭТАПЕ ОБЩЕСТВЕННОГО РАЗВИТИЯ
Authors: БАШУК ОЛЕГ НИКОЛАЕВИЧ
Published: August 2024

Цель работы. В статье рассматриваются понятия и экономическая сущность технологической трансформации промышленности на современном этапе общественного развития. «Методология.» В исследовании использованы методы историко-экономического анализа, теории производственно-технологической сбалансированности экономики, системной парадигмы, эволюционно-институциональной теории, экспертных и аналитических оценок. Результаты. Проведен глубокий анализ технологической трансформации с акцентом на её многоаспектность и комплексность, а также на специфику внедрения и интеграции инновационных технологий в различные сферы промышленного производства в условиях современного меняющегося мира. Также проведено исследование влияния глобальных тенденций на процессы технологической трансформации промышленности, включая анализ требований к изменению управленческих, производственных и бизнес-процессов в контексте текущих экономических и геополитических условий. Сформулировано предложение новых подходов к управлению инновационным развитием, корпоративной культурой и коммуникационными процессами на промышленных предприятиях, учитывающих современные вызовы и требования. Выводы. Современная технологическая трансформация промышленности может стать источником новых возможностей для экономического развития, социального прогресса и устойчивого будущего. Важно учитывать разнообразные факторы и интересы, чтобы создать благоприятные условия для инноваций и развития.
Peculiarities of surgical treatment of scalp soft tissue defects in combat trauma
Authors: Hyndych O. A. , Simulyk Ye. V.
Published: August 2024

Objective. To improve the results of surgical treatment of soft tissue defects of the scalp in combat trauma.
Materials and methods. The study included 9 patients with medium-sized soft tissue defects of the scalp who were treated at the Department of Plastic, Reconstructive and Restorative Surgery of the National Scientific Centre of Surgery and Transplantation named after A.A. Shalimov in 2022-2024.
Results. The use of rotational randomised local flaps to close scalp soft tissue defects has reduced the incidence of postoperative complications, improved the aesthetic outcome of treatment and shortened the rehabilitation period.
Conclusions. The use of rotational randomised local flaps is optimal for closing full-layer soft tissue defects of the medium-sized scalp.
Experimental substantiation of the expediency of using hyperosmolar colloidal solutions for the correction of renal dysfunction in conditions of thermal skin damage
Authors: Tiron O. I. , Khomenko I. P. , Lurin I. A. , Tertyshny S. V. , Stepanov G. F. , Vastyanov R. S.
Published: August 2024

Objective. To study the effectiveness of hyperosmolar colloidal solutions of lactoprotein with sorbitol and HAES–LX 5% on changes in renal functional activity in the dynamics of thermal skin damage.
Materials and methods. The study was conducted under conditions of a chronic experiment on a model of skin burn injury. The concentration of lipoperoxidation intermediates and the activity of antioxidant enzymes in kidney homogenates was determined 1, 3, 7, 14, 21 and 30 days after thermal skin burn. The functional activity of the kidneys was determined using the model of induced water diuresis.
Results. We have demonstrated marked impairment of filtration, excretory and detoxification functions of the kidneys within 30 days of the post–burn period, as well as acceleration of lipoperoxidation and inhibition of antioxidant defence activity. The saline solution had no thermoprotective effect in the skin burn model. The use of hyperosmolar colloidal solutions of lactoprotein with sorbitol and HAES–LX 5% effectively prevented the free radical mechanism of nephrocyte damage and activation of the enzymatic link of antioxidant defence. The optimum protective activity of the hyperosmolar colloidal solutions of lactoprotein with sorbitol and HAES–LX 5% occurred on days 7–14 of the experiment and lasted until its completion.
Conclusions. The scheme of pharmacological correction of thermal damage to the thyroid gland with the introduction of hyperosmolar colloidal solutions with a multionic composition of lactoprotein with sorbitol and HAES–LX 5% is pathogenetically justified, can not only restore the functional activity of nephrocytes, but also prevent their damage in the dynamics of the postburn process.
Checklist of freshwater red algae (Rhodophyta) in Bosnia and Herzegovina
Authors: Šovran Sanja , Knežević Ana , Mašić Ermin
Published: August 2024

The paper provides an overview of all freshwater red algae species recorded to date in the territory of Bosnia and Herzegovina. Based on fieldwork and analysis of all available previously published data, it was determined that a total of 15 taxa from eight genera have been recorded to date: Bangia (1), Audoinella (3), Batrachospermum (2), Peludicola (1), Shaethia (1), Lemanea (4), Paralemanea (2) and Hildenbrandia (1). All taxa were found in clear, cold, well-oxygenated water. Bosnia and Herzegovina is very rich in different types of aquatic habitats. More than 100 sites were visited during the field research, but there are still many potential habitats where freshwater red algae can be found, which will be explored in the coming years. This work is the first step toward establishing long-term monitoring and listing of protected and threatened red algae in Bosnia and Herzegovina.
Evaluation of selected heavy metal and selenium pollution in water and sediments of Lake Eğirdir (Isparta/Türkiye) using statistical analysis and pollution indices
Authors: Özçelik Şule , Tekin-Özan Selda
Published: August 2024

The purpose of this study is to assess heavy metal and selenium pollution in water and sediment of Lake Eğirdir using some indices. The water and sediments have the highest content of Fe. According to Water Quality Index (WQI) results, the lake water is in the good category, while the low pollution category depends on HPI and HEI values. The Enrichment Factor (EF) showed that the sediments contained very high, extremely high and significant levels of Pb, Cr, Cu, Mn, Ni and Fe. The Geoaccumulation Index (Igeo) revealed that Lake Eğirdir was not polluted with Cr, Cu, Fe, Mn, Mo, Ni and Zn. Based on the results of the Contamination Factor (CF), Cr, Cu, Fe, Mn, Mo, Ni and Zn were in the low contamination category. The results of The Pollution Load Index (PLI) for lake sediments indicated no contamination for all metals in all seasons. Sediment quality guidelines were used to determine the possible risk of heavy metal contamination of sediments, and the results show that Cd and Pb were at the minimal effect threshold (MET), while Cr, Cu, Ni and Zn were at the lowest effect levels (LEL). These results indicate that precautions should be taken to prevent an increase in metal pollution and reduce the existing pollution.
Fragrant garden roses for landscaping and aerophytotherapy areas
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Bardakova S.A.
Published: August 2024

The aroma of 324 varieties of roses of garden groups was evaluated: hybrid tea (Hybrid Tea), floribunda (Floribunda), miniature (Miniature), shrub (Shrub), climbing large-flowered (Large-Flowered Climber) in the collection of the Stavropol Botanical Garden. It was revealed that 36 varieties of hybrid tea roses, 11 varieties of floribunda roses, 3 varieties of miniature roses, 18 varieties of shrubs, 6 varieties of large-flowered climbing roses have a pronounced aroma. 90 varieties of hybrid tea roses, 12 varieties of floribunda roses, 7 varieties of miniature roses, 2 varieties of shrub roses, 10 varieties of large-flowered climbing roses have a medium pronounced aroma. The aroma is weakly expressed or absent in varieties of hybrid tea roses, 46 varieties of floribunda roses, 30 varieties of miniature roses, 11 varieties of shrub roses, 4 varieties of large-flowered climbing roses. The perception and description of the aroma is different for each variety, it can resemble several types of aroma of flowering and non-flowering plants. It was found that the air temperature at the stage of budding and flowering, the time of day, humidity – all this can radically affect the aroma. The strongest aroma is observed in the morning hours from 9 am to 11 am. Fragrant garden roses can be used not only in ornamental gardening, but also be part of aromatherapy zones. Varieties of tested garden groups, which received 2 and 3 points on the basis of aroma, are recommended by us for the creation of phyto zones of natural aromatherapy in parks, which are used as part of health complexes, private gardens, sanatoriums and boarding houses for various purposes in the North Caucasus Federal District.
Biological features of some species of the family labiatae, the range of distribution, and the prospect of their use in landscaping
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Peshchanskaya E.V.
Published: August 2024

The purpose of the research is to study the biological characteristics, distribution area, and the possibility of using 18 species of the family of Clear-cut flowers in landscaping. The study of biological features and distribution areas of plant species is one of the fundamental elements of successful plant introduction and study. The conditions of the Stavropol upland belong to the zone of unstable humidification of the Stavropol Territory, are characterized by a temperate continental climate, the altitude above sea level is 640 m., the absolute temperature minimum is –31°C, the absolute maximum temperature is + 39.7°C. The frost-free period is 180…190 days. In the study of 18 species of the Labiatae family, the range of their distribution of species was described according to literary data, regular observations were carried out and their ecological and biological plasticity and peculiarities of cultivation were studied. The distribution range of the studied species is quite wide – most are found throughout the European part, in the Urals, Siberia, the Far East, and Central Asia of the Asian part of the continent. Most species are represented by winter-green herbaceous perennials, as well as biennials – Sage nutmeg, herbaceous perennials – Motherwort cordial, dwarf semishrub – Thyme Marshall, Thyme creeping, Thyme ordinary, half-shrub – Hyssop officinal, evergreen shrubs – Spicate lavender, Sage garden. All plants are responsive to watering, tolerate drought, suitable for growing in the light, the Hyssop officinal, Melissa medicinal, Catnip musina, Baikal scullcap, Motherwort cordial tolerate partial shade. All species are propagated by seeds (except peppermint), most by bush division and cuttings. Pests and diseases are slightly affected. The conducted research allows us to recommend plants for use not only for medicinal purposes, but also for use in landscaping in various techniques and styles. Their ability to enrich the air with essential oils, that suppress pathogenic microflora will significantly improve the quality of human life in overpopulated cities.
Introduction of ornamental shrubs and prospects for their use in landscaping
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Chebannaya L.P.
Published: August 2024

The purpose of the study is to summarize the results of the introduction, to select the most stable and highly decorative shrubs to expand the assortment in landscape gardening in the Stavropol territory. The object of research was a collection of ornamental shrubs, numbering 255 taxa, cultivated in the Stavropol Botanical Garden. The following genera are represented by a significant number of species and varieties: Berberis L., Hydrangea L., Spiraea L., Weigela Thunb. As a result of the introduction test, an assortment of species and varieties with high decorative qualities and adaptive capabilities was identified for practical use in new conditions. The characteristics of decorative qualities, flowering periods and the period of general decorativeness in the soil and climatic conditions of the Stavropol Upland are given. According to the variety of decorative features, the assortment is divided into beautifully flowering, decorative deciduous and beautifully fruiting shrubs. The basis of the collection is made up of beautifully flowering shrubs that play an important role in landscape gardening compositions. Attracting garden forms with original colors of leaves and fruits makes it possible to increase the overall decorative effect of the composition for a longer period. In the collection, 32% of the total composition is occupied by decorative deciduous shrubs. Over a long period of introduction, about 100 highly decorative and locally resistant species and varieties of ornamental shrubs were selected and successfully introduced into landscape gardening in the Stavropol region. The range of resistant, ornamental shrubs in the region is expanding through the selection of its own varieties. Two decorative deciduous varieties of Thunberg barberry “Ruslan” and “Styopka”, bred by the Stavropol Botanical Garden, were included in the State Register of Breeding Achievements.